# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- IKBKB_SDD PF18397.1 KIK31371.1 - 0.081 12.2 0.1 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain FtsA PF14450.6 KIK31373.1 - 0.61 10.5 3.6 2.4 8.6 3.6 2.0 1 1 0 1 1 1 0 Cell division protein FtsA Tom6 PF17112.5 KIK31380.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal Ketoacyl-synt_C PF02801.22 KIK31382.1 - 3.2e-05 23.9 0.1 3.2e-05 23.9 0.1 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain EKR PF10371.9 KIK31382.1 - 0.077 12.8 0.0 0.079 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function RNase_H PF00075.24 KIK31390.1 - 2.4e-06 27.8 0.3 4.1e-06 27.0 0.1 1.5 2 0 0 2 2 2 1 RNase H Phage_TTP_12 PF16461.5 KIK31390.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.5 1 1 1 2 2 2 0 Lambda phage tail tube protein, TTP SMN PF06003.12 KIK31394.1 - 0.18 11.0 1.7 0.29 10.3 1.7 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF1815 PF08844.10 KIK31395.1 - 0.084 12.9 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) Herpes_UL49_5 PF05702.11 KIK31395.1 - 0.085 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein EF-1_beta_acid PF10587.9 KIK31396.1 - 0.02 15.4 1.1 0.055 13.9 1.1 1.8 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region PGA2 PF07543.12 KIK31398.1 - 0.038 14.0 5.0 0.11 12.5 4.6 1.7 2 0 0 2 2 2 0 Protein trafficking PGA2 Di19_C PF14571.6 KIK31398.1 - 0.13 12.8 0.2 0.45 11.1 0.0 1.9 1 1 1 2 2 2 0 Stress-induced protein Di19, C-terminal Borrelia_P83 PF05262.11 KIK31398.1 - 0.24 9.8 5.1 0.31 9.5 5.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PDZ_2 PF13180.6 KIK31401.1 - 0.082 13.2 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 PDZ domain MRPL52 PF18699.1 KIK31415.1 - 0.085 13.1 7.3 6.1 7.1 0.1 3.0 2 1 0 2 2 2 0 Mitoribosomal protein mL52 WD40 PF00400.32 KIK31417.1 - 3.5e-23 81.4 3.8 1.5e-08 35.1 0.1 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31417.1 - 1.1e-05 25.6 0.0 0.027 14.7 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK31417.1 - 0.022 13.4 0.0 1.4 7.4 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 TPR_10 PF13374.6 KIK31424.1 - 0.00052 19.8 17.1 0.042 13.7 0.1 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK31424.1 - 0.003 17.8 8.5 0.81 10.0 3.2 3.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK31424.1 - 0.0085 16.4 1.4 0.42 11.1 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK31424.1 - 0.015 15.4 0.4 33 5.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK31424.1 - 0.035 14.2 7.8 6.6 7.1 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4471 PF14740.6 KIK31424.1 - 0.035 13.3 0.0 0.41 9.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) TPR_7 PF13176.6 KIK31424.1 - 0.081 13.0 2.7 1.6 9.0 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK31424.1 - 0.46 10.2 4.6 9 6.1 0.1 3.2 3 0 0 3 3 3 0 TPR repeat TPR_14 PF13428.6 KIK31424.1 - 1.2 10.1 8.1 2 9.4 0.6 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK31424.1 - 1.3 9.8 9.9 24 5.7 5.4 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIK31425.1 - 0.0034 17.6 0.0 0.037 14.3 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TMEM95 PF15203.6 KIK31426.1 - 0.2 11.3 0.0 0.24 11.0 0.0 1.1 1 0 0 1 1 1 0 TMEM95 family DUF1908 PF08926.11 KIK31429.1 - 0.12 11.4 0.6 0.15 11.1 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) 2-Hacid_dh_C PF02826.19 KIK31430.1 - 0.0018 17.7 0.0 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KIK31430.1 - 0.002 18.7 0.0 0.0024 18.4 0.0 1.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 KIK31430.1 - 0.01 15.7 1.4 0.012 15.5 0.5 1.6 1 1 1 2 2 2 0 Rossmann-like domain ApbA PF02558.16 KIK31430.1 - 0.012 15.3 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KIK31430.1 - 0.017 15.0 0.2 0.023 14.6 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KIK31430.1 - 0.076 13.2 0.0 0.097 12.8 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RasGEF PF00617.19 KIK31431.1 - 0.0009 19.5 0.0 0.0022 18.2 0.0 1.6 1 1 1 2 2 2 1 RasGEF domain Pkinase PF00069.25 KIK31434.1 - 1.1e-16 61.0 0.0 1.4e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK31434.1 - 1.4e-07 31.1 0.0 1.9e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK31434.1 - 7e-06 25.1 0.2 8.4e-06 24.8 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK31434.1 - 0.0021 18.0 0.1 0.11 12.4 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK31434.1 - 0.0029 17.2 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.11 KIK31434.1 - 0.011 14.7 0.1 0.016 14.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KIK31434.1 - 0.027 13.8 0.1 0.045 13.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4731 PF15875.5 KIK31434.1 - 0.037 14.2 0.0 3.2 8.0 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4731) KDZ PF18758.1 KIK31435.1 - 5e-29 101.5 2.1 5.8e-29 101.3 2.1 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase WD40 PF00400.32 KIK31436.1 - 0.00036 21.3 0.6 0.0075 17.1 0.4 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.8 KIK31436.1 - 0.0084 14.8 0.0 0.0084 14.8 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK31436.1 - 0.22 10.8 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 WD40-like domain PDDEXK_1 PF12705.7 KIK31437.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily zf_UBZ PF18439.1 KIK31441.1 - 0.068 12.8 0.1 0.16 11.6 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Plavaka PF18759.1 KIK31442.1 - 2e-86 290.2 0.0 2.3e-86 289.9 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase GREB1 PF15782.5 KIK31447.1 - 2.3 5.2 7.2 2.6 5.1 7.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MMM1 PF10296.9 KIK31447.1 - 4.7 6.2 6.0 5.1 6.0 6.0 1.0 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 TPR_12 PF13424.6 KIK31449.1 - 6.8e-06 26.3 1.8 0.024 14.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK31449.1 - 6.6e-05 22.7 0.3 0.33 11.2 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK31449.1 - 0.00011 22.7 1.0 0.36 11.8 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK31449.1 - 0.0026 17.5 1.2 1 9.3 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK31449.1 - 0.0026 17.4 0.0 2.1 8.1 0.0 3.2 3 1 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 KIK31449.1 - 0.0031 17.6 0.0 2.6 8.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIK31449.1 - 0.0062 16.4 5.1 0.27 11.2 0.3 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK31449.1 - 0.044 14.3 1.4 15 6.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIK31449.1 - 0.18 12.2 1.0 3.2 8.3 0.1 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat Transketolase_N PF00456.21 KIK31451.1 - 2e-10 40.2 0.5 1.4e-09 37.4 0.0 1.9 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain DUF3007 PF11460.8 KIK31453.1 - 0.023 14.9 0.0 0.027 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) PDDEXK_1 PF12705.7 KIK31455.1 - 0.043 13.7 0.1 0.053 13.4 0.1 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily CHAT PF12770.7 KIK31461.1 - 4e-42 144.6 0.0 4.8e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 CHAT domain zf-H3C2 PF16721.5 KIK31462.1 - 0.17 12.2 0.0 0.2 12.0 0.0 1.1 1 0 0 1 1 1 0 Zinc-finger like, probable DNA-binding DUF3025 PF11227.8 KIK31464.1 - 0.013 15.3 0.1 0.016 15.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) GCD14 PF08704.10 KIK31465.1 - 0.061 13.0 0.1 0.066 12.9 0.1 1.0 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF3025 PF11227.8 KIK31468.1 - 0.078 12.8 0.2 0.08 12.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) Phosducin PF02114.16 KIK31470.1 - 2.3e-06 26.8 0.0 0.0018 17.3 0.0 2.3 2 1 0 2 2 2 2 Phosducin Myb_DNA-bind_4 PF13837.6 KIK31471.1 - 8e-08 32.6 0.1 1.1e-07 32.2 0.1 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 KIK31471.1 - 0.00021 22.2 0.1 0.00029 21.7 0.1 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Helicase_C PF00271.31 KIK31473.1 - 6.7e-11 42.5 0.0 1.1e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.6 KIK31473.1 - 0.02 15.1 0.1 0.098 12.8 0.1 1.7 1 1 1 2 2 2 0 Helicase C-terminal domain Aldo_ket_red PF00248.21 KIK31475.1 - 2.6e-07 30.2 0.0 3e-07 29.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Use1 PF09753.9 KIK31477.1 - 0.11 12.2 1.9 0.12 12.1 1.9 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 HTH_33 PF13592.6 KIK31478.1 - 2.3e-06 27.1 0.0 2.7e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 Winged helix-turn helix Arg_repressor PF01316.21 KIK31478.1 - 0.022 14.5 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain DDE_3 PF13358.6 KIK31479.1 - 0.078 12.7 0.0 0.081 12.7 0.0 1.0 1 0 0 1 1 1 0 DDE superfamily endonuclease zf-RING_5 PF14634.6 KIK31480.1 - 0.62 10.1 4.7 1.6 8.8 4.7 1.7 1 1 0 1 1 1 0 zinc-RING finger domain DUF4886 PF16227.5 KIK31482.1 - 0.023 13.9 0.2 0.024 13.9 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4886) Pkinase PF00069.25 KIK31483.1 - 3e-24 85.8 0.0 7.2e-24 84.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK31483.1 - 3.4e-16 59.3 0.1 1.1e-15 57.6 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase SPC25 PF06703.11 KIK31483.1 - 0.091 12.5 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) OAD_gamma PF04277.13 KIK31484.1 - 0.092 13.4 0.0 0.1 13.2 0.0 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF2973 PF11189.8 KIK31484.1 - 0.67 10.1 0.0 0.67 10.1 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2973) Plavaka PF18759.1 KIK31487.1 - 1.1e-12 47.9 0.3 4.8e-09 35.9 0.0 2.1 1 1 1 2 2 2 2 Plavaka transposase Pkinase_fungal PF17667.1 KIK31489.1 - 8.5e-31 107.1 0.0 1.7e-28 99.6 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 KIK31489.1 - 1.7e-05 24.9 0.0 2.4e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIK31489.1 - 0.022 14.1 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain WD40 PF00400.32 KIK31491.1 - 1.2e-45 152.6 33.8 4.2e-08 33.7 0.9 7.4 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31491.1 - 5.1e-19 68.4 4.6 0.00018 21.7 0.0 6.0 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK31491.1 - 1.5e-07 30.7 0.4 0.31 9.9 0.0 5.9 1 1 5 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK31491.1 - 4.9e-07 28.8 6.0 0.017 13.8 0.6 4.2 2 1 2 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.12 KIK31491.1 - 0.00099 19.0 0.5 19 5.4 0.1 5.1 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK31491.1 - 0.0047 16.3 0.0 0.46 9.7 0.0 3.0 2 1 1 3 3 3 1 WD40-like domain Frtz PF11768.8 KIK31491.1 - 0.007 14.7 0.1 0.074 11.4 0.0 2.4 3 0 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz SGL PF08450.12 KIK31491.1 - 0.0075 15.9 0.3 0.085 12.4 0.3 2.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region MMS1_N PF10433.9 KIK31491.1 - 0.01 14.5 0.0 0.03 13.0 0.0 1.8 3 0 0 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Nbas_N PF15492.6 KIK31491.1 - 0.055 12.8 1.4 0.34 10.2 0.1 2.8 3 2 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Lactonase PF10282.9 KIK31491.1 - 0.075 12.3 0.0 0.3 10.3 0.0 1.9 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller DUF4082 PF13313.6 KIK31491.1 - 0.41 10.7 3.4 1.8 8.6 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4082) TFIIA PF03153.13 KIK31492.1 - 0.075 13.0 12.8 0.084 12.9 12.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 KIK31492.1 - 0.083 11.0 15.4 0.083 11.0 15.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 KIK31492.1 - 0.15 11.4 13.9 0.38 10.1 12.9 1.8 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.12 KIK31492.1 - 0.44 9.8 12.9 0.54 9.5 12.9 1.2 1 0 0 1 1 1 0 NOA36 protein PI3K_1B_p101 PF10486.9 KIK31492.1 - 0.5 8.1 4.5 0.58 7.9 4.5 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TFB6 PF17110.5 KIK31492.1 - 0.81 9.4 7.4 1.1 9.0 7.4 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Zip PF02535.22 KIK31492.1 - 2.5 7.2 5.4 3.2 6.9 5.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 KIK31492.1 - 7 4.8 15.8 8 4.6 15.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_L15e PF00827.17 KIK31496.1 - 0.051 13.3 0.2 0.3 10.8 0.2 2.0 1 1 0 1 1 1 0 Ribosomal L15 LRR_4 PF12799.7 KIK31497.1 - 0.0013 19.1 0.1 0.0021 18.4 0.1 1.4 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIK31497.1 - 0.12 12.2 0.2 0.22 11.3 0.2 1.4 1 1 0 1 1 1 0 Leucine rich repeat Ig_mannosidase PF17753.1 KIK31498.1 - 7.7e-13 48.0 0.1 1.5e-12 47.1 0.0 1.5 2 0 0 2 2 2 1 Ig-fold domain gag-asp_proteas PF13975.6 KIK31499.1 - 9.3e-06 26.1 0.0 1.3e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIK31499.1 - 4.2e-05 24.1 0.0 6.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KIK31499.1 - 7.5e-05 22.5 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KIK31499.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease NAD_binding_2 PF03446.15 KIK31505.1 - 0.00078 19.6 0.0 0.012 15.8 0.0 2.0 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KIK31505.1 - 0.02 15.5 0.0 0.025 15.2 0.0 1.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KIK31505.1 - 0.072 12.7 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KIK31505.1 - 0.098 12.5 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KIK31505.1 - 0.1 11.9 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Plavaka PF18759.1 KIK31508.1 - 1e-11 44.7 0.0 1.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase ANAPC16 PF17256.2 KIK31509.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 16 Cauli_VI PF01693.16 KIK31510.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Caulimovirus viroplasmin HSP70 PF00012.20 KIK31511.1 - 3.2e-06 25.6 0.1 3.9e-06 25.3 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein Plavaka PF18759.1 KIK31512.1 - 2.8e-16 59.6 0.0 3e-16 59.6 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2 PF00096.26 KIK31513.1 - 0.0037 17.6 0.9 0.0037 17.6 0.9 1.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_9 PF16293.5 KIK31513.1 - 0.024 14.5 0.1 0.061 13.2 0.1 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf-C2H2_4 PF13894.6 KIK31513.1 - 0.024 15.4 0.6 0.024 15.4 0.6 2.3 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 KIK31513.1 - 0.47 10.4 2.6 0.71 9.8 0.5 2.0 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Pkinase_fungal PF17667.1 KIK31514.1 - 4.4e-10 38.9 0.0 4.7e-10 38.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase FAD_binding_3 PF01494.19 KIK31519.1 - 3e-09 36.6 0.0 3.8e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK31519.1 - 5.7e-06 25.8 0.2 0.06 12.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK31519.1 - 4.3e-05 22.4 0.1 0.037 12.7 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 KIK31519.1 - 0.00035 20.3 0.7 0.1 12.1 0.0 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK31519.1 - 0.00073 18.7 0.2 0.0012 18.1 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KIK31519.1 - 0.0017 17.3 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_8 PF13450.6 KIK31519.1 - 0.006 16.8 0.1 0.024 14.9 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIK31519.1 - 0.0093 15.2 0.0 0.087 12.1 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIK31519.1 - 0.016 14.6 0.1 0.021 14.2 0.1 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIK31519.1 - 0.03 14.9 0.1 8.2 7.1 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KIK31519.1 - 0.061 12.6 0.0 5.6 6.1 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Microcephalin PF12258.8 KIK31521.1 - 0.19 10.9 2.4 0.24 10.6 2.4 1.1 1 0 0 1 1 1 0 Microcephalin protein Alpha-mann_mid PF09261.11 KIK31523.1 - 2.5e-18 66.0 0.0 1.1e-16 60.7 0.0 2.3 2 1 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro_38N PF01074.22 KIK31523.1 - 2.9e-07 30.1 0.0 3.6e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain DDE_Tnp_4 PF13359.6 KIK31524.1 - 0.044 13.5 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Alpha-mann_mid PF09261.11 KIK31525.1 - 1.2e-27 95.9 0.0 3.4e-26 91.2 0.0 2.1 2 0 0 2 2 2 2 Alpha mannosidase middle domain DUF2778 PF10908.8 KIK31526.1 - 0.005 17.1 0.3 0.0066 16.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2778) LTD PF00932.19 KIK31526.1 - 0.04 14.3 0.0 0.041 14.2 0.0 1.2 1 0 0 1 1 1 0 Lamin Tail Domain Plavaka PF18759.1 KIK31527.1 - 7.3e-53 179.9 0.0 9.7e-53 179.5 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase WD40 PF00400.32 KIK31529.1 - 2.7e-10 40.6 1.2 1.2e-09 38.6 0.7 2.4 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31529.1 - 0.015 15.5 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK31529.1 - 0.072 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein KDZ PF18758.1 KIK31531.1 - 5.9e-35 120.9 0.9 3.5e-33 115.1 0.9 2.2 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Exonuc_VII_S PF02609.16 KIK31531.1 - 0.46 10.6 1.9 1.4 9.0 0.0 2.5 3 0 0 3 3 3 0 Exonuclease VII small subunit CxC2 PF18803.1 KIK31532.1 - 1.8e-44 150.3 0.0 1.8e-44 150.3 0.0 2.0 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK31532.1 - 1.2e-05 25.4 0.0 2.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIK31532.1 - 0.00048 19.8 0.0 0.00087 19.0 0.0 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC3 PF18804.1 KIK31532.1 - 0.0053 16.6 0.0 0.0053 16.6 0.0 2.2 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases CxC5 PF18718.1 KIK31533.1 - 2.7e-21 75.8 3.8 3.5e-21 75.5 3.8 1.1 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases Mating_C PF12737.7 KIK31540.1 - 0.0025 17.1 8.0 0.0029 16.9 8.0 1.1 1 0 0 1 1 1 1 C-terminal domain of homeodomain 1 DTHCT PF08070.11 KIK31540.1 - 0.12 13.1 11.3 0.22 12.3 11.3 1.4 1 1 0 1 1 1 0 DTHCT (NUC029) region NAM-associated PF14303.6 KIK31540.1 - 0.16 12.7 5.2 0.2 12.3 5.2 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SR-25 PF10500.9 KIK31540.1 - 0.25 10.9 9.2 0.35 10.5 9.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GEMIN8 PF15348.6 KIK31540.1 - 1.2 9.3 5.7 1.3 9.3 5.7 1.0 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Plavaka PF18759.1 KIK31541.1 - 1.5e-54 185.5 0.1 1.9e-54 185.1 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase Retrotran_gag_2 PF14223.6 KIK31542.1 - 1.5e-05 24.7 0.0 2.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type RVP PF00077.20 KIK31542.1 - 0.18 12.2 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease NSs PF11073.8 KIK31543.1 - 0.03 13.8 0.0 0.031 13.7 0.0 1.0 1 0 0 1 1 1 0 Rift valley fever virus non structural protein (NSs) like Hydrolase PF00702.26 KIK31545.1 - 0.0023 18.3 0.0 0.0027 18.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PlyB_C PF18684.1 KIK31545.1 - 0.16 11.7 0.0 0.49 10.1 0.0 1.6 1 1 1 2 2 2 0 Pleurotolysin B C-terminal domain WD40 PF00400.32 KIK31549.1 - 1.8e-18 66.5 2.1 2.3e-07 31.4 0.1 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31549.1 - 2.1e-05 24.7 0.0 0.0055 17.0 0.0 2.5 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Antig_Caf1 PF09255.10 KIK31549.1 - 0.015 15.4 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Caf1 Capsule antigen Nup160 PF11715.8 KIK31549.1 - 0.083 11.5 0.3 0.71 8.4 0.1 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 zf-RVT PF13966.6 KIK31553.1 - 1.8e-05 25.3 0.9 2.6e-05 24.9 0.9 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Plavaka PF18759.1 KIK31555.1 - 7e-17 61.6 0.0 8.6e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase Ribosomal_S30AE PF02482.19 KIK31556.1 - 0.13 13.1 0.0 0.23 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein WD40 PF00400.32 KIK31558.1 - 1.2e-32 111.4 19.9 1.6e-06 28.7 0.0 7.1 6 1 1 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.11 KIK31558.1 - 3.1e-10 40.2 0.0 0.00087 19.2 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KIK31558.1 - 8.2e-09 35.7 0.2 0.12 12.7 0.0 5.4 1 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK31558.1 - 1.3e-05 24.3 0.0 0.0079 15.2 0.0 2.6 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK31558.1 - 0.00011 22.1 0.1 1.1 9.3 0.0 4.5 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Big_7 PF17957.1 KIK31558.1 - 0.012 16.4 3.0 1.3 9.8 0.5 3.3 2 1 1 3 3 3 0 Bacterial Ig domain Nucleoporin_N PF08801.11 KIK31558.1 - 0.022 13.5 0.6 0.89 8.2 0.2 2.9 2 1 0 3 3 3 0 Nup133 N terminal like Proteasome_A_N PF10584.9 KIK31558.1 - 0.24 11.1 0.8 1.4e+02 2.3 0.0 4.2 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature START PF01852.19 KIK31561.1 - 5e-05 22.8 0.0 9.7e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 START domain MPM1 PF17234.2 KIK31562.1 - 0.0019 18.5 0.4 0.0029 17.9 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial peculiar membrane protein 1 RAP1 PF07218.11 KIK31563.1 - 0.015 13.6 0.8 0.016 13.5 0.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Prot_ATP_ID_OB PF16450.5 KIK31563.1 - 0.095 12.7 0.4 0.17 11.8 0.4 1.4 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain Transposase_21 PF02992.14 KIK31569.1 - 1.9e-08 33.8 0.0 2.3e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 zf-CCHC PF00098.23 KIK31573.1 - 0.029 14.5 7.7 0.093 12.8 3.1 2.5 2 1 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 KIK31573.1 - 0.16 11.7 2.8 0.33 10.7 2.8 1.5 1 0 0 1 1 1 0 Zinc knuckle Macoilin PF09726.9 KIK31574.1 - 0.084 11.4 0.9 0.085 11.4 0.9 1.0 1 0 0 1 1 1 0 Macoilin family WD40 PF00400.32 KIK31575.1 - 5.7e-21 74.4 8.5 0.00042 21.1 0.0 4.6 4 1 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31575.1 - 4.7e-05 23.6 0.2 0.42 10.9 0.0 2.9 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain KDZ PF18758.1 KIK31578.1 - 1e-27 97.2 0.0 1.3e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK31578.1 - 0.00063 19.9 0.1 0.0012 18.9 0.1 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases SfsA_N PF17746.1 KIK31578.1 - 0.12 12.6 0.0 0.97 9.6 0.0 2.1 2 0 0 2 2 2 0 SfsA N-terminal OB domain Mfa_like_2 PF15415.6 KIK31578.1 - 0.17 10.8 0.0 0.35 9.7 0.0 1.4 2 0 0 2 2 2 0 Fimbrillin-like Plavaka PF18759.1 KIK31581.1 - 2.7e-10 40.0 0.0 3.6e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase MOR2-PAG1_N PF14222.6 KIK31582.1 - 0.014 14.4 0.0 0.018 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Helicase_C PF00271.31 KIK31583.1 - 6.3e-11 42.6 0.0 1.6e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK31583.1 - 2.1e-10 40.6 0.5 1.4e-09 38.0 0.5 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIK31583.1 - 0.0036 17.3 0.0 0.014 15.4 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Cnn_1N PF07989.11 KIK31584.1 - 0.062 13.5 0.2 0.09 12.9 0.2 1.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Swi5 PF07061.11 KIK31584.1 - 0.19 11.8 0.3 0.3 11.2 0.3 1.3 1 0 0 1 1 1 0 Swi5 KOW PF00467.29 KIK31585.1 - 0.01 15.8 0.2 0.019 14.9 0.2 1.5 1 0 0 1 1 1 0 KOW motif Antistasin PF02822.14 KIK31586.1 - 0.41 11.3 5.6 11 6.7 0.2 2.8 2 1 1 3 3 3 0 Antistasin family Parvo_NS1 PF01057.17 KIK31588.1 - 7.7e-07 28.5 0.1 9.2e-07 28.2 0.1 1.1 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 TIP49 PF06068.13 KIK31588.1 - 0.00037 19.8 0.0 0.00038 19.8 0.0 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 KIK31588.1 - 0.00042 20.7 0.0 0.00049 20.5 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KIK31588.1 - 0.0017 17.6 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 KIK31588.1 - 0.0057 17.1 0.1 0.011 16.2 0.1 1.5 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK31588.1 - 0.0077 16.6 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 KIK31588.1 - 0.0081 16.4 0.0 0.0093 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 KIK31588.1 - 0.01 14.8 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain NACHT PF05729.12 KIK31588.1 - 0.01 15.7 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain APS_kinase PF01583.20 KIK31588.1 - 0.011 15.7 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 KIK31588.1 - 0.012 15.3 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KIK31588.1 - 0.017 15.0 0.0 0.019 14.9 0.0 1.1 1 0 0 1 1 1 0 Rad17 P-loop domain PhoH PF02562.16 KIK31588.1 - 0.019 14.5 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.6 KIK31588.1 - 0.022 15.1 0.0 0.026 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KIK31588.1 - 0.024 13.8 0.0 0.026 13.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Torsin PF06309.11 KIK31588.1 - 0.033 14.3 0.0 0.037 14.1 0.0 1.1 1 0 0 1 1 1 0 Torsin T2SSE PF00437.20 KIK31588.1 - 0.034 13.2 0.0 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 KIK31588.1 - 0.039 14.1 0.0 0.049 13.7 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain Cytidylate_kin PF02224.18 KIK31588.1 - 0.04 13.7 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase AAA_7 PF12775.7 KIK31588.1 - 0.048 13.2 0.0 0.055 13.0 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region PIF1 PF05970.14 KIK31588.1 - 0.057 12.6 0.0 0.062 12.5 0.0 1.0 1 0 0 1 1 1 0 PIF1-like helicase Mg_chelatase PF01078.21 KIK31588.1 - 0.096 12.1 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KIK31588.1 - 0.096 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KIK31588.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 KIK31588.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KIK31588.1 - 0.19 11.6 0.0 0.22 11.4 0.0 1.0 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RuvB_N PF05496.12 KIK31588.1 - 0.21 11.3 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RT_RNaseH_2 PF17919.1 KIK31589.1 - 1.3e-11 44.3 0.0 6.1e-11 42.2 0.0 1.8 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KIK31589.1 - 9.1e-05 22.7 0.0 0.00013 22.2 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PP2C_2 PF13672.6 KIK31589.1 - 0.025 14.2 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C Glyco_tranf_2_4 PF13704.6 KIK31589.1 - 0.092 13.3 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 2 OrsD PF12013.8 KIK31591.1 - 2.9e-08 34.1 3.7 2.9e-08 34.1 3.7 1.9 2 1 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 KIK31591.1 - 0.015 16.1 6.0 0.9 10.6 1.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Actin_micro PF17003.5 KIK31591.1 - 0.076 12.2 2.5 1.9 7.6 2.5 2.0 1 1 0 1 1 1 0 Putative actin-like family zf-C2H2_2 PF12756.7 KIK31591.1 - 3.2 8.1 9.6 6.1 7.2 1.6 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KIK31594.1 - 0.0067 16.8 0.2 0.015 15.7 0.2 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK31594.1 - 0.038 14.8 0.2 0.12 13.3 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KIK31594.1 - 0.044 13.7 1.7 0.093 12.7 1.7 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Zn-C2H2_12 PF18112.1 KIK31594.1 - 0.13 12.8 2.4 0.86 10.1 0.2 2.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-CCHC PF00098.23 KIK31595.1 - 0.042 13.9 8.3 0.095 12.8 3.1 2.6 2 1 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 KIK31595.1 - 0.13 12.0 3.0 0.29 10.9 3.0 1.6 1 0 0 1 1 1 0 Zinc knuckle XPG_I PF00867.18 KIK31596.1 - 2.7e-18 66.1 0.0 4.1e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KIK31596.1 - 3.1e-05 24.4 0.0 0.00013 22.3 0.0 2.0 1 1 0 1 1 1 1 XPG N-terminal domain Fur_reg_FbpA PF13076.6 KIK31596.1 - 0.013 15.2 0.3 0.022 14.4 0.3 1.4 1 0 0 1 1 1 0 Fur-regulated basic protein A XPG_I_2 PF12813.7 KIK31596.1 - 0.036 13.5 0.1 0.05 13.1 0.1 1.2 1 0 0 1 1 1 0 XPG domain containing OrsD PF12013.8 KIK31597.1 - 3.4e-09 37.1 3.1 1.1e-08 35.6 3.1 1.8 1 1 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 KIK31597.1 - 0.0015 19.2 4.2 0.085 13.7 1.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger DUF629 PF04780.12 KIK31597.1 - 0.14 10.7 4.3 4.7 5.6 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF629) Actin_micro PF17003.5 KIK31597.1 - 0.18 10.9 1.2 1.5 8.0 1.2 1.9 1 1 0 1 1 1 0 Putative actin-like family zf-Di19 PF05605.12 KIK31597.1 - 0.24 11.7 5.3 1.3 9.3 0.4 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KIK31597.1 - 1.1 9.9 4.3 2.2 8.9 1.0 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KIK31597.1 - 1.9 8.9 6.5 11 6.5 0.5 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Dimer_Tnp_hAT PF05699.14 KIK31598.1 - 4.4e-14 52.0 0.0 4.6e-14 52.0 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Vasculin PF15337.6 KIK31604.1 - 0.075 13.9 0.0 0.13 13.1 0.0 1.3 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 Pallilysin PF18663.1 KIK31604.1 - 0.095 12.7 0.1 1.5 8.8 0.0 2.1 2 0 0 2 2 2 0 Pallilysin beta barrel domain Pkinase PF00069.25 KIK31609.1 - 0.0021 17.4 0.0 0.0025 17.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ketoacyl-synt_C PF02801.22 KIK31611.1 - 0.00066 19.7 0.3 0.0013 18.8 0.3 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain p450 PF00067.22 KIK31615.1 - 8.3e-45 153.4 0.0 9.8e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EzrA PF06160.12 KIK31620.1 - 0.0017 16.6 0.9 0.0023 16.2 0.9 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Mer2 PF09074.10 KIK31620.1 - 0.02 14.7 0.7 0.02 14.7 0.7 1.9 1 1 1 2 2 2 0 Mer2 DASH_Dam1 PF08653.10 KIK31620.1 - 0.032 14.1 0.5 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 zf-C4H2 PF10146.9 KIK31620.1 - 0.045 14.1 0.2 0.056 13.7 0.2 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein DUF948 PF06103.11 KIK31620.1 - 0.54 10.5 2.7 12 6.2 0.2 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) WD40 PF00400.32 KIK31622.1 - 0.11 13.4 0.4 0.38 11.7 0.4 1.9 1 1 0 1 1 1 0 WD domain, G-beta repeat PhnA_Zn_Ribbon PF08274.12 KIK31623.1 - 0.24 11.4 2.6 10 6.1 0.1 3.1 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Pkinase_fungal PF17667.1 KIK31624.1 - 1.1e-11 44.2 0.0 1.2e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Herpes_UL6 PF01763.16 KIK31624.1 - 0.1 11.1 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Pkinase_fungal PF17667.1 KIK31625.1 - 6.2e-17 61.5 0.0 7.2e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase WD40 PF00400.32 KIK31627.1 - 6.6e-05 23.6 0.4 0.00026 21.7 0.2 2.2 1 1 1 2 2 2 1 WD domain, G-beta repeat KDZ PF18758.1 KIK31628.1 - 4.8e-05 23.1 0.0 6.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK31628.1 - 8.5e-05 22.7 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases PHINT_rpt PF14882.6 KIK31628.1 - 0.033 14.5 0.1 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 Phage-integrase repeat unit TPR_12 PF13424.6 KIK31629.1 - 0.00056 20.1 0.9 3 8.2 0.0 3.8 4 1 0 4 4 4 2 Tetratricopeptide repeat Apolipoprotein PF01442.18 KIK31630.1 - 0.0039 17.1 0.2 0.0046 16.9 0.2 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF2673 PF10880.8 KIK31630.1 - 0.0077 16.3 0.3 0.0098 16.0 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2673) Endotoxin_C2 PF18449.1 KIK31630.1 - 0.011 16.0 1.3 0.017 15.5 1.3 1.2 1 0 0 1 1 1 0 Delta endotoxin Laminin_II PF06009.12 KIK31630.1 - 0.011 15.7 1.8 0.015 15.3 1.7 1.3 1 1 0 1 1 1 0 Laminin Domain II DUF677 PF05055.12 KIK31630.1 - 0.019 13.9 0.5 0.02 13.8 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) WD40 PF00400.32 KIK31631.1 - 1.1e-31 108.3 18.5 5.9e-09 36.4 3.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31631.1 - 9.5e-16 57.9 3.2 0.00032 20.9 0.3 4.1 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KIK31631.1 - 1.2e-07 31.4 0.8 1.2e-05 24.8 0.0 2.9 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 KIK31631.1 - 1.4e-06 27.5 0.0 0.15 10.9 0.0 3.5 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK31631.1 - 2.3e-06 26.6 0.3 0.34 9.5 0.1 3.3 2 2 2 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK31631.1 - 7.4e-05 22.2 0.0 1.4 8.2 0.0 3.5 3 1 0 3 3 3 2 WD40-like domain eIF2A PF08662.11 KIK31631.1 - 0.00015 21.7 0.5 0.0024 17.8 0.3 2.3 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KIK31631.1 - 0.0013 17.4 0.1 0.0086 14.6 0.0 2.0 1 1 1 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.12 KIK31631.1 - 0.03 14.3 0.1 3 7.9 0.0 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Peptidase_S9_N PF02897.15 KIK31631.1 - 0.067 12.0 0.1 0.12 11.2 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain PALB2_WD40 PF16756.5 KIK31631.1 - 0.085 11.8 4.2 2.7 6.8 0.0 2.5 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Arena_nucleocap PF00843.17 KIK31631.1 - 0.5 9.2 3.9 11 4.9 0.5 3.1 2 1 1 3 3 3 0 Arenavirus nucleocapsid N-terminal domain Fungal_trans PF04082.18 KIK31632.1 - 6.8e-07 28.6 0.0 1.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3_C PF01915.22 KIK31633.1 - 5.2e-15 55.9 0.0 6.1e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain PA14 PF07691.12 KIK31633.1 - 5.5e-14 52.2 0.0 8.3e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 PA14 domain B5 PF03484.15 KIK31636.1 - 7.5 6.9 8.8 40 4.6 8.8 2.1 1 1 0 1 1 1 0 tRNA synthetase B5 domain Aa_trans PF01490.18 KIK31637.1 - 1.7e-28 99.5 8.8 2e-28 99.3 8.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KIK31637.1 - 1.5e-08 34.1 8.7 1.9e-08 33.8 8.7 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family WD40 PF00400.32 KIK31639.1 - 2.7e-20 72.3 8.7 5e-09 36.6 1.9 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31639.1 - 5.4e-06 26.6 0.1 0.15 12.4 0.0 2.7 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK31639.1 - 0.0026 16.8 0.0 0.21 10.5 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK31639.1 - 0.017 13.8 0.9 0.063 11.9 0.1 1.9 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK31639.1 - 0.036 13.4 0.9 0.86 8.9 0.0 2.6 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Plavaka PF18759.1 KIK31641.1 - 8.7e-73 245.4 0.0 1.1e-72 245.0 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase Imm31 PF15591.6 KIK31641.1 - 0.041 13.7 0.1 0.079 12.8 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 31 zf-C2H2 PF00096.26 KIK31641.1 - 0.075 13.5 0.2 0.22 12.1 0.2 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type ANAPC4_WD40 PF12894.7 KIK31644.1 - 8.7e-08 32.4 0.0 1.1e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK31644.1 - 4.3e-05 24.2 1.2 4.3e-05 24.2 1.2 2.0 2 1 0 2 2 2 1 WD domain, G-beta repeat Plavaka PF18759.1 KIK31649.1 - 3.9e-90 302.4 0.1 4.8e-90 302.1 0.1 1.1 1 0 0 1 1 1 1 Plavaka transposase MPS-4 PF17523.2 KIK31650.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 WD40 PF00400.32 KIK31653.1 - 3.1e-46 154.4 15.2 3.5e-08 34.0 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31653.1 - 3.8e-15 56.0 0.9 0.023 15.0 0.1 5.6 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WW PF00397.26 KIK31653.1 - 4.6e-06 26.6 2.4 2e-05 24.5 0.7 3.0 2 0 0 2 2 2 1 WW domain Nup160 PF11715.8 KIK31653.1 - 1.1e-05 24.3 0.2 0.067 11.8 0.1 4.0 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK31653.1 - 0.0014 18.0 0.1 0.46 9.8 0.0 2.9 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 KIK31653.1 - 0.0042 16.1 0.1 1.1 8.1 0.0 3.6 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KIK31653.1 - 0.098 11.4 0.4 6.5 5.4 0.2 3.2 3 1 1 4 4 4 0 Nup133 N terminal like DUF3558 PF12079.8 KIK31653.1 - 0.12 12.4 0.2 0.72 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3558) Cep57_CLD_2 PF14197.6 KIK31656.1 - 0.00068 19.7 2.2 0.0012 18.9 2.2 1.4 1 1 0 1 1 1 1 Centrosome localisation domain of PPC89 TPR_2 PF07719.17 KIK31658.1 - 0.0063 16.5 0.0 3.1 8.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_21 PF09976.9 KIK31658.1 - 0.017 14.9 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain PPTA PF01239.22 KIK31658.1 - 0.062 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat TauD PF02668.16 KIK31659.1 - 2.5e-05 24.2 0.1 2.9e-05 24.0 0.1 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PapD-like PF14874.6 KIK31659.1 - 0.11 12.6 0.0 0.15 12.3 0.0 1.3 1 1 0 1 1 1 0 Flagellar-associated PapD-like CK_II_beta PF01214.18 KIK31661.1 - 0.0037 17.1 4.5 0.0039 17.0 4.5 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Retrotran_gag_2 PF14223.6 KIK31662.1 - 2.2e-07 30.6 0.0 3.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KIK31662.1 - 4.7e-05 22.9 0.1 0.00012 21.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Ada3 PF10198.9 KIK31662.1 - 0.012 15.8 0.1 0.021 15.0 0.1 1.3 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 Poly_export PF02563.16 KIK31662.1 - 0.15 12.3 0.1 0.25 11.6 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis/export protein Dimer_Tnp_hAT PF05699.14 KIK31665.1 - 1.1e-07 31.5 0.0 1.4e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase_fungal PF17667.1 KIK31666.1 - 1.5e-22 80.0 0.0 1.9e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK31666.1 - 1.3e-06 28.0 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK31666.1 - 0.078 12.2 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Plavaka PF18759.1 KIK31667.1 - 1.7e-16 60.4 0.0 2.5e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase WD40 PF00400.32 KIK31668.1 - 3.3e-39 132.2 22.0 3.4e-07 30.9 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31668.1 - 6.8e-10 39.1 1.2 0.22 11.8 0.0 5.2 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WW PF00397.26 KIK31668.1 - 8.8e-06 25.7 2.6 2.3e-05 24.4 0.4 2.9 3 0 0 3 3 3 1 WW domain DUF3558 PF12079.8 KIK31668.1 - 0.00016 21.8 0.9 0.4 10.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3558) Ge1_WD40 PF16529.5 KIK31668.1 - 0.00021 20.4 0.1 16 4.4 0.0 4.7 2 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK31668.1 - 0.00044 20.2 0.0 0.17 11.7 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK31668.1 - 0.0005 18.9 0.1 0.5 9.0 0.1 3.2 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KIK31668.1 - 0.0061 15.3 0.0 2.9 6.5 0.0 2.6 3 0 0 3 3 3 2 Nup133 N terminal like Nbas_N PF15492.6 KIK31668.1 - 0.033 13.5 0.1 5.5 6.2 0.0 2.8 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.12 KIK31668.1 - 0.055 11.5 0.0 1.6 6.6 0.0 2.8 4 0 0 4 4 4 0 IKI3 family WD40 PF00400.32 KIK31669.1 - 1.8e-30 104.5 6.3 1.3e-08 35.3 2.4 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31669.1 - 5.1e-15 55.5 0.4 1.9e-05 24.9 0.0 3.2 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK31669.1 - 6.9e-06 25.0 0.2 0.24 10.0 0.0 3.0 1 1 1 3 3 3 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK31669.1 - 3e-05 23.5 0.0 0.00013 21.4 0.0 1.8 2 0 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 KIK31669.1 - 0.00053 19.0 0.0 0.16 10.9 0.0 2.9 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 KIK31669.1 - 0.00084 19.2 0.0 5.5 7.1 0.0 3.5 3 0 0 3 3 3 2 PQQ enzyme repeat eIF2A PF08662.11 KIK31669.1 - 0.0033 17.3 0.0 0.024 14.5 0.0 1.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KIK31669.1 - 0.0065 15.8 0.1 0.23 10.8 0.0 2.4 1 1 1 2 2 2 1 Neuroblastoma-amplified sequence, N terminal PQQ_3 PF13570.6 KIK31669.1 - 0.035 14.6 1.1 5.5 7.6 1.2 2.9 2 1 1 3 3 3 0 PQQ-like domain RAB3GAP2_N PF14655.6 KIK31669.1 - 0.066 12.5 0.0 0.47 9.7 0.0 1.9 1 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40 PF00400.32 KIK31670.1 - 1.8e-35 120.3 13.6 1.2e-09 38.6 0.1 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31670.1 - 1.1e-16 60.9 0.0 2e-05 24.8 0.0 4.1 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK31670.1 - 1.1e-05 24.6 0.0 5.1 5.9 0.0 4.0 2 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK31670.1 - 0.00014 20.7 0.2 1.1 7.8 0.0 3.7 3 1 1 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK31670.1 - 0.0037 17.2 0.1 0.018 14.9 0.1 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK31670.1 - 0.021 14.8 2.4 27 4.8 0.1 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF3060 PF11259.8 KIK31670.1 - 0.022 14.4 0.0 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3060) NHR2 PF08788.11 KIK31676.1 - 0.16 11.8 0.2 0.35 10.7 0.1 1.6 2 0 0 2 2 2 0 NHR2 domain like Plavaka PF18759.1 KIK31677.1 - 1e-35 123.5 0.0 1.4e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase EndoU_bacteria PF14436.6 KIK31677.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial EndoU nuclease XPB_DRD PF18458.1 KIK31677.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Xeroderma pigmentosum group B helicase damage recognition domain Plavaka PF18759.1 KIK31678.1 - 1.8e-19 70.2 0.1 2.3e-19 69.8 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase Dimer_Tnp_hAT PF05699.14 KIK31679.1 - 7.4e-09 35.3 0.0 7.8e-09 35.2 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DNA_pol_A_exo1 PF01612.20 KIK31684.1 - 3.5e-10 39.9 0.0 5.3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease KDZ PF18758.1 KIK31685.1 - 0.0011 18.6 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK31685.1 - 0.0012 19.0 0.1 0.0036 17.4 0.0 1.9 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases PDE6_gamma PF04868.12 KIK31686.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit Pkinase PF00069.25 KIK31688.1 - 1.2e-18 67.5 0.0 1.5e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK31688.1 - 1.4e-09 37.6 0.0 2.1e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK31688.1 - 7.2e-07 28.3 0.2 8.5e-07 28.1 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK31688.1 - 0.00056 19.9 0.1 0.011 15.6 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK31688.1 - 0.00078 19.1 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KIK31688.1 - 0.018 14.4 0.1 0.032 13.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KIK31688.1 - 0.061 12.3 0.1 0.088 11.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 KIK31688.1 - 0.083 11.9 0.2 0.19 10.7 0.1 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 Clathrin PF00637.20 KIK31690.1 - 8.4e-12 45.2 0.2 1.3e-11 44.5 0.2 1.3 1 0 0 1 1 1 1 Region in Clathrin and VPS AAA_12 PF13087.6 KIK31690.1 - 0.025 14.2 0.2 0.031 13.9 0.2 1.1 1 0 0 1 1 1 0 AAA domain Cauli_VI PF01693.16 KIK31691.1 - 3.3e-06 27.3 0.0 4.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Caulimovirus viroplasmin Pkinase_fungal PF17667.1 KIK31692.1 - 2.5e-43 148.4 0.0 1.4e-35 122.8 0.0 2.0 1 1 1 2 2 2 2 Fungal protein kinase DUF4934 PF16288.5 KIK31693.1 - 0.2 11.6 0.0 0.24 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4934) Integrase_H2C2 PF17921.1 KIK31694.1 - 5.6e-07 29.6 3.6 8.8e-07 28.9 3.6 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain Integrase_H2C2 PF17921.1 KIK31695.1 - 0.0038 17.3 0.5 0.03 14.4 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain Pkinase PF00069.25 KIK31697.1 - 9.4e-42 143.2 0.0 1.1e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK31697.1 - 1.8e-15 57.0 0.0 2.2e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIK31697.1 - 0.00016 21.1 0.2 0.00025 20.5 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK31697.1 - 0.00017 20.5 0.2 0.00025 20.0 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIK31697.1 - 0.0081 15.5 0.0 0.011 15.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KIK31697.1 - 0.013 15.4 0.0 0.59 10.0 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF604 PF04646.12 KIK31697.1 - 0.077 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF604 Haspin_kinase PF12330.8 KIK31697.1 - 0.092 11.7 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Zn-C2H2_12 PF18112.1 KIK31698.1 - 0.047 14.2 0.3 0.27 11.7 0.0 2.2 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Dimer_Tnp_hAT PF05699.14 KIK31699.1 - 5.1e-08 32.6 0.0 8.8e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CENP-T_C PF15511.6 KIK31699.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Sex_peptide PF08138.11 KIK31701.1 - 0.14 12.3 0.6 0.25 11.5 0.6 1.4 1 0 0 1 1 1 0 Sex peptide (SP) family CIAPIN1 PF05093.13 KIK31709.1 - 0.00051 20.5 0.2 0.0011 19.5 0.2 1.5 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF3584 PF12128.8 KIK31709.1 - 0.00075 17.2 6.7 0.00097 16.8 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) HAUS5 PF14817.6 KIK31709.1 - 0.0021 16.9 5.3 0.0028 16.5 5.3 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 Exonuc_VII_L PF02601.15 KIK31709.1 - 0.0076 15.9 1.3 0.0084 15.7 1.3 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit YscO-like PF16789.5 KIK31709.1 - 0.013 15.5 7.7 0.022 14.8 7.7 1.3 1 0 0 1 1 1 0 YscO-like protein Uso1_p115_C PF04871.13 KIK31709.1 - 0.015 15.6 10.9 0.025 14.9 10.9 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region ATG16 PF08614.11 KIK31709.1 - 0.02 15.1 9.4 0.033 14.4 9.4 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) PHD PF00628.29 KIK31709.1 - 0.034 14.0 2.8 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 PHD-finger Atg14 PF10186.9 KIK31709.1 - 0.038 13.1 5.7 0.058 12.5 5.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NAP PF00956.18 KIK31709.1 - 0.043 13.0 1.0 0.055 12.6 1.0 1.1 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) DUF2461 PF09365.10 KIK31709.1 - 0.06 13.3 0.4 0.089 12.7 0.4 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) SWIRM-assoc_1 PF16495.5 KIK31709.1 - 0.11 12.4 9.0 0.25 11.3 9.0 1.6 1 1 0 1 1 1 0 SWIRM-associated region 1 Spc7 PF08317.11 KIK31709.1 - 0.14 11.0 9.3 0.21 10.4 9.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 KIK31709.1 - 0.18 12.4 11.8 0.33 11.6 11.8 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SlyX PF04102.12 KIK31709.1 - 0.44 11.2 11.2 4.9 7.9 9.7 2.4 1 1 1 2 2 2 0 SlyX Macoilin PF09726.9 KIK31709.1 - 0.64 8.5 8.2 0.84 8.1 8.2 1.1 1 0 0 1 1 1 0 Macoilin family OmpH PF03938.14 KIK31709.1 - 0.66 10.3 12.6 1.2 9.5 12.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GrpE PF01025.19 KIK31709.1 - 1.3 8.7 10.0 0.21 11.3 5.5 1.8 1 1 1 2 2 2 0 GrpE DUF349 PF03993.12 KIK31709.1 - 1.3 9.4 12.7 1 9.7 10.6 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) zf-C3HC4_3 PF13920.6 KIK31709.1 - 1.4 8.8 3.9 0.83 9.6 0.9 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3450 PF11932.8 KIK31709.1 - 2.9 7.1 10.3 5.4 6.3 10.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Fzo_mitofusin PF04799.13 KIK31709.1 - 4.2 6.9 8.2 6.9 6.2 8.2 1.2 1 0 0 1 1 1 0 fzo-like conserved region Presenilin PF01080.17 KIK31709.1 - 5.2 5.7 4.5 6.8 5.3 4.5 1.1 1 0 0 1 1 1 0 Presenilin DUF16 PF01519.16 KIK31709.1 - 5.2 7.6 8.0 14 6.2 8.0 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF615 PF04751.14 KIK31713.1 - 0.0097 15.9 0.3 0.018 15.0 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF615) DUF3035 PF11233.8 KIK31715.1 - 0.12 12.7 0.0 0.14 12.5 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3035) RRM_1 PF00076.22 KIK31717.1 - 3.7e-11 42.7 0.0 5.3e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OrfB_IS605 PF01385.19 KIK31717.1 - 0.021 15.0 0.6 0.048 13.9 0.6 1.5 1 0 0 1 1 1 0 Probable transposase Nup35_RRM PF05172.13 KIK31717.1 - 0.035 14.1 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KIK31717.1 - 0.11 12.5 0.1 0.26 11.3 0.1 1.6 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF1045 PF06299.12 KIK31717.1 - 0.15 12.0 2.5 0.32 11.0 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) DUF3464 PF11947.8 KIK31717.1 - 2.1 8.1 4.3 3.6 7.3 4.3 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 RS4NT PF08071.12 KIK31721.1 - 1.1e-06 28.7 0.6 1.5e-06 28.2 0.6 1.3 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KIK31721.1 - 0.00019 21.1 0.1 0.00025 20.7 0.1 1.1 1 0 0 1 1 1 1 S4 domain Sgf11 PF08209.11 KIK31723.1 - 0.13 11.9 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) Tudor_3 PF18115.1 KIK31724.1 - 1.9e-09 37.2 0.3 2.2e-08 33.8 0.1 2.4 2 1 0 2 2 2 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KIK31724.1 - 5.4e-05 23.2 0.1 0.00011 22.2 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4537) Tudor_2 PF18104.1 KIK31724.1 - 6e-05 22.6 2.0 0.0035 17.0 0.0 2.7 2 0 0 2 2 2 1 Jumonji domain-containing protein 2A Tudor domain DUF1325 PF07039.11 KIK31724.1 - 0.00028 21.0 0.0 0.00091 19.3 0.0 1.8 2 0 0 2 2 2 1 SGF29 tudor-like domain TUDOR_5 PF18359.1 KIK31724.1 - 0.0081 15.8 0.1 0.44 10.3 0.0 2.3 2 0 0 2 2 2 1 Histone methyltransferase Tudor domain 1 Rad9_Rad53_bind PF08605.10 KIK31724.1 - 0.012 15.8 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding DUF1681 PF07933.14 KIK31724.1 - 0.019 14.7 0.0 0.032 13.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1681) 53-BP1_Tudor PF09038.10 KIK31724.1 - 0.03 14.3 0.1 0.051 13.5 0.1 1.5 1 1 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor Furin-like_2 PF15913.5 KIK31727.1 - 0.017 15.2 1.1 0.02 15.0 1.1 1.1 1 0 0 1 1 1 0 Furin-like repeat, cysteine-rich gag-asp_proteas PF13975.6 KIK31730.1 - 1.3e-07 32.1 0.2 2.1e-07 31.4 0.1 1.3 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIK31730.1 - 1.7e-07 31.8 0.1 2.2e-07 31.4 0.1 1.3 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KIK31730.1 - 3.8e-07 29.9 0.0 4.7e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 KIK31730.1 - 0.07 12.9 0.0 0.083 12.7 0.0 1.1 1 0 0 1 1 1 0 Aspartyl protease CxC5 PF18718.1 KIK31734.1 - 8.9e-25 87.0 1.5 1.3e-24 86.5 1.5 1.2 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases XPG_I PF00867.18 KIK31735.1 - 0.017 15.4 0.0 0.031 14.6 0.0 1.3 1 0 0 1 1 1 0 XPG I-region Tachylectin PF14517.6 KIK31738.1 - 0.025 14.1 0.1 0.05 13.1 0.1 1.4 1 1 0 1 1 1 0 Tachylectin DNA_pol_phi PF04931.13 KIK31738.1 - 2.4 6.1 6.5 2.9 5.9 6.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF1192 PF06698.11 KIK31739.1 - 0.11 12.6 2.8 0.2 11.7 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) WD40 PF00400.32 KIK31740.1 - 6.7e-09 36.2 2.4 1.2e-08 35.4 0.6 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31740.1 - 0.082 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain DASH_Spc19 PF08287.11 KIK31742.1 - 0.31 10.9 7.1 0.11 12.4 3.5 2.0 3 0 0 3 3 3 0 Spc19 Uso1_p115_C PF04871.13 KIK31742.1 - 0.39 11.1 11.7 0.15 12.4 9.2 1.6 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region HMG_box PF00505.19 KIK31742.1 - 0.53 10.7 7.1 0.18 12.3 4.0 1.8 2 0 0 2 2 2 0 HMG (high mobility group) box Pet100 PF09803.9 KIK31742.1 - 4.6 7.8 9.5 47 4.6 6.7 3.1 2 1 0 2 2 2 0 Pet100 HemolysinCabind PF00353.19 KIK31743.1 - 0.0007 19.5 4.1 2.7 8.1 0.2 4.1 4 0 0 4 4 4 2 RTX calcium-binding nonapeptide repeat (4 copies) Cyt-b5 PF00173.28 KIK31743.1 - 0.015 15.5 0.0 13 6.1 0.0 3.4 3 0 0 3 3 3 0 Cytochrome b5-like Heme/Steroid binding domain L_protein_N PF15518.6 KIK31744.1 - 0.092 12.6 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 L protein N-terminus DUF805 PF05656.14 KIK31745.1 - 0.0051 17.2 0.3 0.0055 17.1 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF805) TraL PF07178.11 KIK31745.1 - 0.024 15.1 0.4 0.028 14.9 0.4 1.0 1 0 0 1 1 1 0 TraL protein Chitin_synth_2 PF03142.15 KIK31746.1 - 1.3e-25 90.0 0.0 1.5e-25 89.8 0.0 1.0 1 0 0 1 1 1 1 Chitin synthase Glycos_transf_2 PF00535.26 KIK31746.1 - 0.03 14.1 0.0 0.038 13.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 2 Chitin_synth_1 PF01644.17 KIK31747.1 - 1e-29 103.6 0.1 1.1e-29 103.5 0.1 1.0 1 0 0 1 1 1 1 Chitin synthase RVT_1 PF00078.27 KIK31748.1 - 0.0039 16.7 0.1 0.0039 16.7 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retinal PF15449.6 KIK31750.1 - 0.013 13.4 1.0 0.013 13.3 1.0 1.0 1 0 0 1 1 1 0 Retinal protein Spt5_N PF11942.8 KIK31750.1 - 0.016 16.2 4.6 0.016 16.2 4.6 2.2 2 1 1 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Gon7 PF08738.10 KIK31750.1 - 0.11 12.5 0.6 0.26 11.4 0.6 1.6 1 0 0 1 1 1 0 Gon7 family UBN_AB PF14075.6 KIK31751.1 - 0.01 15.5 0.0 0.011 15.4 0.0 1.0 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Peptidase_C48 PF02902.19 KIK31757.1 - 0.00013 21.9 0.0 0.00014 21.8 0.0 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C39 PF03412.15 KIK31757.1 - 0.0015 18.3 0.1 0.0019 18.0 0.1 1.1 1 0 0 1 1 1 1 Peptidase C39 family Peptidase_C48 PF02902.19 KIK31758.1 - 1.3e-07 31.7 0.9 1.3e-07 31.7 0.9 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DEK_C PF08766.11 KIK31761.1 - 5.1e-07 29.5 0.0 1.3e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 DEK C terminal domain HSF_DNA-bind PF00447.17 KIK31762.1 - 1.7e-15 57.4 0.1 1.8e-15 57.3 0.1 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 KIK31762.1 - 0.014 15.9 0.0 0.017 15.6 0.0 1.2 1 0 0 1 1 1 0 Ets-domain KDZ PF18758.1 KIK31764.1 - 1.7e-34 119.4 2.1 4.8e-33 114.7 2.1 2.4 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DBD_Tnp_Mut PF03108.15 KIK31764.1 - 0.0037 17.2 1.9 0.025 14.6 1.0 2.4 2 0 0 2 2 2 1 MuDR family transposase MerR-DNA-bind PF09278.11 KIK31764.1 - 2.3 8.8 5.0 0.87 10.2 0.6 2.6 3 0 0 3 3 3 0 MerR, DNA binding WD40 PF00400.32 KIK31766.1 - 1.9e-44 148.7 20.3 2.3e-07 31.4 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31766.1 - 2.7e-13 50.0 0.9 0.003 17.8 0.0 5.2 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WW PF00397.26 KIK31766.1 - 2.2e-06 27.6 0.9 2.2e-06 27.6 0.9 2.6 3 0 0 3 3 3 1 WW domain DUF3558 PF12079.8 KIK31766.1 - 0.0006 19.9 0.1 0.033 14.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3558) Ge1_WD40 PF16529.5 KIK31766.1 - 0.0019 17.2 0.1 2.5 7.0 0.0 3.4 2 2 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK31766.1 - 0.0038 15.9 0.3 6.9 5.2 0.1 3.7 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Gmad1 PF10647.9 KIK31766.1 - 0.044 13.5 0.3 8.3 6.1 0.0 3.2 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain WD40_like PF17005.5 KIK31766.1 - 0.074 12.4 0.0 1.9 7.7 0.0 2.5 2 1 0 2 2 2 0 WD40-like domain WD40 PF00400.32 KIK31769.1 - 3.4e-26 91.0 1.5 5.3e-08 33.4 0.2 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31769.1 - 9.8e-07 29.0 0.0 1.2 9.5 0.0 3.7 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK31769.1 - 0.0034 16.1 0.0 0.014 14.0 0.0 1.8 2 0 0 2 2 2 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK31769.1 - 0.0043 16.4 0.0 1.1 8.5 0.0 2.2 1 1 1 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 KIK31769.1 - 0.023 13.6 0.0 0.11 11.5 0.0 1.8 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Sad1_UNC PF07738.13 KIK31770.1 - 1.3e-13 51.1 0.0 1.8e-06 28.0 0.0 2.1 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal zf-RING_UBOX PF13445.6 KIK31772.1 - 0.00011 22.1 6.0 0.00011 22.1 6.0 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIK31772.1 - 0.00012 21.8 5.0 0.00024 20.9 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK31772.1 - 0.00021 21.6 5.7 0.00044 20.5 5.7 1.5 1 0 0 1 1 1 1 Ring finger domain DUF3584 PF12128.8 KIK31772.1 - 0.0013 16.4 4.4 0.0016 16.1 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) zf-C3HC4 PF00097.25 KIK31772.1 - 0.0014 18.5 4.9 0.0035 17.2 4.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CIAPIN1 PF05093.13 KIK31772.1 - 0.0025 18.3 0.5 0.0025 18.3 0.5 1.8 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis zf-C3HC4_3 PF13920.6 KIK31772.1 - 0.003 17.4 3.4 0.006 16.4 3.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KIK31772.1 - 0.0068 16.5 2.5 0.016 15.3 2.5 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KIK31772.1 - 0.012 15.4 1.7 0.021 14.7 1.7 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein HAUS5 PF14817.6 KIK31772.1 - 0.021 13.6 6.9 0.027 13.2 6.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 ATG16 PF08614.11 KIK31772.1 - 0.024 14.8 7.8 0.035 14.3 7.8 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KIK31772.1 - 0.035 13.0 6.2 0.047 12.6 6.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-C3HC4_4 PF15227.6 KIK31772.1 - 0.035 14.3 5.4 0.035 14.3 5.4 2.0 3 0 0 3 3 2 0 zinc finger of C3HC4-type, RING SlyX PF04102.12 KIK31772.1 - 0.068 13.8 9.6 0.5 11.0 7.9 2.3 1 1 1 2 2 2 0 SlyX Exonuc_VII_L PF02601.15 KIK31772.1 - 0.07 12.7 3.1 0.09 12.3 3.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF16 PF01519.16 KIK31772.1 - 0.16 12.5 3.4 0.31 11.6 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 GrpE PF01025.19 KIK31772.1 - 0.39 10.4 7.4 0.16 11.6 4.6 1.7 1 1 1 2 2 2 0 GrpE OmpH PF03938.14 KIK31772.1 - 0.83 10.0 11.3 1.5 9.1 11.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) zf-RING_5 PF14634.6 KIK31772.1 - 1.2 9.2 10.6 0.068 13.1 4.8 1.9 2 0 0 2 2 2 0 zinc-RING finger domain Fzo_mitofusin PF04799.13 KIK31772.1 - 2.6 7.6 6.0 3.9 7.0 6.0 1.2 1 0 0 1 1 1 0 fzo-like conserved region RasGEF PF00617.19 KIK31774.1 - 1.1e-14 55.1 0.0 1.6e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain WD40 PF00400.32 KIK31776.1 - 4e-32 109.7 8.8 2.6e-09 37.5 0.3 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31776.1 - 8e-07 29.3 0.0 0.034 14.5 0.0 3.7 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK31776.1 - 0.0011 18.0 0.0 0.85 8.5 0.0 2.3 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK31776.1 - 0.0035 16.0 0.0 0.028 13.1 0.0 2.3 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK31776.1 - 0.021 14.1 0.5 1.7 7.9 0.0 2.9 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK31776.1 - 0.056 12.8 0.0 3.1 7.0 0.0 2.1 1 1 0 2 2 2 0 WD40-like domain HARP PF07443.13 KIK31776.1 - 0.14 11.9 0.1 16 5.2 0.0 3.0 3 0 0 3 3 3 0 HepA-related protein (HARP) KDZ PF18758.1 KIK31777.1 - 6.8e-86 287.5 0.0 8.6e-86 287.1 0.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK31777.1 - 0.011 15.8 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases zf_C2H2_10 PF18414.1 KIK31777.1 - 0.02 14.4 0.5 0.041 13.4 0.5 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger CxC2 PF18803.1 KIK31777.1 - 0.034 14.3 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK31777.1 - 0.071 13.0 0.0 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases JUPITER PF17054.5 KIK31779.1 - 0.061 12.8 0.2 0.061 12.8 0.2 1.1 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter WD40 PF00400.32 KIK31781.1 - 4.7e-07 30.4 0.0 6.6e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31781.1 - 0.031 14.6 0.0 0.031 14.6 0.0 1.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK31783.1 - 2.5e-36 123.1 24.4 1.7e-06 28.6 0.1 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31783.1 - 8.3e-19 67.7 9.0 3.6e-06 27.2 0.1 6.3 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK31783.1 - 3.9e-06 26.1 0.0 0.23 10.4 0.0 3.8 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK31783.1 - 2.6e-05 23.1 3.1 0.65 8.6 0.1 3.9 3 1 1 4 4 4 3 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KIK31783.1 - 0.00056 20.3 5.0 0.092 13.3 0.1 4.5 4 0 0 4 4 4 1 PQQ-like domain Nbas_N PF15492.6 KIK31783.1 - 0.0013 18.2 0.2 0.46 9.8 0.0 3.8 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK31783.1 - 0.0044 16.4 0.0 0.092 12.1 0.0 2.7 2 1 2 4 4 4 1 WD40-like domain PD40 PF07676.12 KIK31783.1 - 0.018 15.0 0.0 22 5.1 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PQQ PF01011.21 KIK31783.1 - 0.046 13.7 4.7 9.6 6.3 0.0 5.0 5 0 0 5 5 5 0 PQQ enzyme repeat RAB3GAP2_N PF14655.6 KIK31783.1 - 0.05 12.9 0.0 0.3 10.3 0.0 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PHZA_PHZB PF03284.13 KIK31783.1 - 5.3 6.7 6.0 0.64 9.6 0.5 2.3 2 1 2 4 4 4 0 Phenazine biosynthesis protein A/B WD40 PF00400.32 KIK31787.1 - 6.8e-08 33.1 0.0 1.1e-07 32.4 0.0 1.3 1 0 0 1 1 1 1 WD domain, G-beta repeat Nup160 PF11715.8 KIK31788.1 - 0.031 12.9 0.0 0.031 12.9 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 WD40 PF00400.32 KIK31789.1 - 3.6e-15 56.1 4.4 3.6e-05 24.4 0.0 3.6 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31789.1 - 1e-06 28.9 0.0 0.029 14.7 0.0 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 KIK31789.1 - 0.02 14.7 0.1 0.12 12.2 0.0 1.9 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 KIK31789.1 - 0.023 13.3 0.0 2.9 6.4 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 TehB PF03848.14 KIK31790.1 - 0.15 11.4 0.0 0.18 11.2 0.0 1.0 1 0 0 1 1 1 0 Tellurite resistance protein TehB NB-ARC PF00931.22 KIK31791.1 - 0.0093 15.2 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain APS_kinase PF01583.20 KIK31791.1 - 0.11 12.3 0.1 0.14 12.0 0.1 1.1 1 0 0 1 1 1 0 Adenylylsulphate kinase Parvo_NS1 PF01057.17 KIK31791.1 - 0.14 11.2 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ParA PF10609.9 KIK31791.1 - 0.15 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Torsin PF06309.11 KIK31791.1 - 0.15 12.1 0.0 0.19 11.9 0.0 1.1 1 0 0 1 1 1 0 Torsin AAA_16 PF13191.6 KIK31791.1 - 0.18 12.2 0.0 0.2 12.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain PIF1 PF05970.14 KIK31791.1 - 0.18 10.9 0.0 0.2 10.8 0.0 1.0 1 0 0 1 1 1 0 PIF1-like helicase Rootletin PF15035.6 KIK31794.1 - 0.012 15.7 12.4 0.017 15.1 12.4 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Fmp27_WPPW PF10359.9 KIK31794.1 - 0.031 13.1 8.2 0.04 12.8 8.2 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain FapA PF03961.13 KIK31794.1 - 0.04 12.5 7.9 0.054 12.1 7.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 KIK31794.1 - 0.053 13.1 3.2 0.069 12.7 3.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Zip PF02535.22 KIK31794.1 - 0.11 11.7 0.3 0.14 11.3 0.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter VSG_B PF13206.6 KIK31794.1 - 0.14 11.4 6.6 0.2 10.9 6.6 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain Atg14 PF10186.9 KIK31794.1 - 0.15 11.1 6.4 0.21 10.6 6.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KIK31794.1 - 0.19 12.3 20.5 0.35 11.4 20.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region PDE4_UCR PF18100.1 KIK31794.1 - 0.3 11.7 7.2 0.75 10.4 6.6 1.8 2 0 0 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) V_ATPase_I PF01496.19 KIK31794.1 - 0.38 8.6 10.1 0.51 8.2 10.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LCD1 PF09798.9 KIK31794.1 - 0.73 8.3 16.1 0.98 7.9 16.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein PET10 PF17316.2 KIK31794.1 - 0.99 8.9 4.5 43 3.5 0.0 2.1 2 0 0 2 2 2 0 Petite colonies protein 10 Prominin PF05478.11 KIK31794.1 - 1.2 7.0 4.0 1.6 6.6 4.0 1.1 1 0 0 1 1 1 0 Prominin AAA_11 PF13086.6 KIK31794.1 - 1.9 8.2 10.0 3 7.6 10.0 1.2 1 0 0 1 1 1 0 AAA domain MRP-S27 PF10037.9 KIK31794.1 - 2.5 6.9 11.1 5.1 5.9 11.1 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 EMP24_GP25L PF01105.24 KIK31794.1 - 3.1 7.7 7.0 5.4 6.9 7.0 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD PCRF PF03462.18 KIK31794.1 - 3.6 7.4 12.3 5.8 6.7 12.3 1.3 1 0 0 1 1 1 0 PCRF domain UPF0242 PF06785.11 KIK31794.1 - 4.5 7.3 16.9 7 6.7 16.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 KIK31794.1 - 7.3 6.7 7.3 14 5.7 7.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4670 PF15709.5 KIK31795.1 - 0.017 14.5 3.2 0.024 14.0 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) Cu-oxidase_2 PF07731.14 KIK31796.1 - 1.2e-29 102.8 2.0 1.4e-29 102.5 2.0 1.1 1 0 0 1 1 1 1 Multicopper oxidase Phage_integrase PF00589.22 KIK31799.1 - 0.16 11.7 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Phage integrase family L_lactis_RepB_C PF06430.12 KIK31800.1 - 0.017 15.1 0.1 0.062 13.3 0.1 1.7 1 1 1 2 2 2 0 Lactococcus lactis RepB C-terminus Amidase PF01425.21 KIK31802.1 - 2.1e-31 109.4 0.0 2.4e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 Amidase T3SS_ExsE PF18286.1 KIK31807.1 - 0.052 13.5 0.0 0.99 9.4 0.0 2.4 2 0 0 2 2 2 0 Type III secretion system ExsE WD40 PF00400.32 KIK31809.1 - 7.8e-23 80.3 13.9 1.9e-05 25.3 0.1 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31809.1 - 8.9e-10 38.7 2.3 0.12 12.7 0.1 4.6 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK31809.1 - 3.7e-05 23.7 0.8 9.6e-05 22.3 0.5 1.8 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 KIK31809.1 - 0.001 19.4 1.7 1.5 9.4 0.1 3.2 3 0 0 3 3 3 2 PQQ-like domain Nup160 PF11715.8 KIK31809.1 - 0.012 14.2 2.9 0.21 10.2 0.4 2.4 1 1 0 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.12 KIK31809.1 - 0.091 12.7 0.2 15 5.7 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PRR18 PF15671.5 KIK31810.1 - 0.13 12.1 6.8 1.8 8.4 0.4 2.0 1 1 1 2 2 2 0 Proline-rich protein family 18 Enamelin PF15362.6 KIK31811.1 - 0.036 12.4 1.7 0.037 12.4 1.7 1.0 1 0 0 1 1 1 0 Enamelin KDZ PF18758.1 KIK31812.1 - 1.9e-23 83.2 0.5 2.7e-23 82.8 0.5 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK31812.1 - 7.7e-19 67.8 2.2 9.4e-19 67.6 0.4 2.0 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK31812.1 - 0.0012 18.9 0.3 0.004 17.3 0.0 2.1 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK31812.1 - 0.0075 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases Chitin_synth_2 PF03142.15 KIK31819.1 - 4.8e-11 42.0 0.0 7e-11 41.4 0.0 1.2 1 1 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KIK31819.1 - 7.3e-05 22.8 0.4 8.8e-05 22.5 0.4 1.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.15 KIK31820.1 - 4.2e-23 81.8 0.0 4.5e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 Chitin synthase WD40 PF00400.32 KIK31821.1 - 8.1e-45 149.9 13.5 7.5e-08 32.9 2.7 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31821.1 - 1.8e-20 73.0 9.6 0.00014 22.1 0.1 6.3 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK31821.1 - 1.5e-10 41.2 3.5 2.7e-08 33.9 1.5 2.8 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK31821.1 - 1.5e-08 33.8 4.8 0.094 11.3 0.1 4.1 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK31821.1 - 4.1e-06 26.0 0.0 0.69 8.8 0.0 4.3 2 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK31821.1 - 1.6e-05 24.4 0.0 0.0024 17.3 0.0 3.3 3 1 1 4 4 4 2 WD40-like domain PQQ_3 PF13570.6 KIK31821.1 - 7.7e-05 23.1 1.8 3.2 8.3 0.0 4.7 3 1 1 4 4 4 2 PQQ-like domain Cytochrom_D1 PF02239.16 KIK31821.1 - 0.00075 18.1 0.1 0.0046 15.5 0.0 2.1 1 1 0 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.12 KIK31821.1 - 0.0044 16.9 0.4 90 3.2 0.0 5.6 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat PQQ PF01011.21 KIK31821.1 - 0.0049 16.7 5.0 7.8 6.6 0.1 5.1 5 0 0 5 5 5 1 PQQ enzyme repeat RAB3GAP2_N PF14655.6 KIK31821.1 - 0.0086 15.4 0.3 0.053 12.8 0.0 2.2 2 1 1 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ_2 PF13360.6 KIK31821.1 - 0.012 15.2 9.3 0.024 14.2 4.2 2.9 1 1 1 2 2 2 0 PQQ-like domain TetM_leader PF08076.11 KIK31821.1 - 0.14 12.0 0.1 0.49 10.2 0.0 2.0 2 0 0 2 2 2 0 Tetracycline resistance determinant leader peptide WD40 PF00400.32 KIK31823.1 - 1.1e-18 67.2 11.7 4.3e-06 27.4 0.3 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31823.1 - 0.00012 22.3 0.4 0.0072 16.6 0.2 2.6 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK31823.1 - 0.0016 17.2 0.1 0.097 11.3 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK31823.1 - 0.0059 16.5 0.1 0.12 12.2 0.0 2.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KIK31823.1 - 0.028 13.8 0.1 0.099 12.0 0.0 1.9 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal FUSC PF04632.12 KIK31824.1 - 0.0019 16.8 0.1 0.0027 16.3 0.1 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family WD40 PF00400.32 KIK31827.1 - 1.5e-38 130.0 19.6 5.9e-08 33.2 0.9 7.1 6 1 1 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31827.1 - 1.5e-15 57.2 0.1 0.0027 18.0 0.0 5.4 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK31827.1 - 1e-06 28.8 0.0 0.058 13.3 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK31827.1 - 5.5e-05 22.3 0.4 0.32 9.9 0.1 3.9 2 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK31827.1 - 0.0036 17.2 0.0 3.6 7.6 0.0 4.3 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK31827.1 - 0.061 12.6 0.4 2.7 7.2 0.0 3.2 2 2 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal DUF3929 PF13066.6 KIK31827.1 - 0.16 12.1 0.1 0.58 10.2 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) ECH_1 PF00378.20 KIK31828.1 - 3.2e-27 95.4 0.0 3.7e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIK31828.1 - 8.2e-17 61.7 0.1 1e-16 61.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF3124 PF11322.8 KIK31828.1 - 0.18 12.0 0.1 0.95 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3124) STT3 PF02516.14 KIK31831.1 - 9e-23 80.9 5.5 9.8e-23 80.8 5.5 1.0 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Hydrolase PF00702.26 KIK31835.1 - 0.00042 20.7 0.0 0.00054 20.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase YfkB PF08756.10 KIK31835.1 - 0.029 14.2 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 YfkB-like domain NAPRTase PF04095.16 KIK31841.1 - 0.0089 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Plavaka PF18759.1 KIK31843.1 - 5.1e-25 88.4 0.0 5.4e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase zf-C2HC_2 PF13913.6 KIK31844.1 - 0.15 12.0 0.5 0.26 11.2 0.5 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type F-box-like PF12937.7 KIK31845.1 - 2.1e-06 27.5 0.1 6.4e-06 26.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like Corona_NS8 PF12093.8 KIK31845.1 - 0.042 14.4 0.5 5.5 7.6 0.0 2.6 2 1 0 2 2 2 0 Coronavirus NS8 protein Pkinase_fungal PF17667.1 KIK31846.1 - 0.059 12.1 0.0 0.07 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase FYVE_2 PF02318.16 KIK31847.1 - 0.079 13.2 1.9 0.17 12.1 1.9 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Siva PF05458.12 KIK31847.1 - 0.14 11.9 3.0 0.29 10.8 3.0 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) CK_II_beta PF01214.18 KIK31847.1 - 0.68 9.7 2.7 1.2 8.9 2.7 1.3 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Plavaka PF18759.1 KIK31848.1 - 1.5e-06 27.7 0.0 1.6e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK31849.1 - 2.4e-12 46.7 0.0 3.5e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase CRISPR_Cas9_WED PF18061.1 KIK31850.1 - 0.039 14.0 0.0 0.039 14.0 0.0 1.0 1 0 0 1 1 1 0 CRISPR-Cas9 WED domain MTBP_N PF14918.6 KIK31850.1 - 0.039 13.4 0.0 0.044 13.3 0.0 1.0 1 0 0 1 1 1 0 MDM2-binding RFC1 PF08519.12 KIK31850.1 - 0.085 13.0 0.0 0.085 13.0 0.0 1.1 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain WD40 PF00400.32 KIK31851.1 - 1.6e-40 136.4 21.1 1.2e-08 35.5 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31851.1 - 2e-12 47.2 1.4 0.033 14.5 0.0 4.6 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WW PF00397.26 KIK31851.1 - 2.5e-06 27.4 6.7 3.2e-06 27.1 0.7 3.5 3 0 0 3 3 3 1 WW domain Nup160 PF11715.8 KIK31851.1 - 7.3e-05 21.6 0.2 0.034 12.8 0.4 2.7 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KIK31851.1 - 0.0051 15.6 0.1 0.5 9.1 0.1 2.7 3 1 0 3 3 3 2 Nup133 N terminal like Hira PF07569.11 KIK31851.1 - 0.032 14.0 0.1 0.4 10.4 0.0 2.1 1 1 1 2 2 2 0 TUP1-like enhancer of split zf-RVT PF13966.6 KIK31853.1 - 0.015 16.0 0.4 0.025 15.3 0.4 1.4 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Plavaka PF18759.1 KIK31858.1 - 6.7e-88 295.0 3.0 8.8e-88 294.6 3.0 1.1 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2 PF00096.26 KIK31858.1 - 0.0051 17.2 1.5 0.0051 17.2 1.5 2.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KIK31858.1 - 0.009 16.3 0.2 0.026 14.8 0.2 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KIK31858.1 - 0.041 14.7 0.9 0.041 14.7 0.9 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger MMR_HSR1 PF01926.23 KIK31860.1 - 5.1e-08 33.0 0.0 8e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK31860.1 - 4.2e-05 23.5 0.0 0.025 14.5 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 KIK31860.1 - 0.00023 20.7 0.2 0.0022 17.5 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KIK31860.1 - 0.00064 19.9 0.7 0.0035 17.6 0.0 2.3 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 KIK31860.1 - 0.0046 17.4 0.0 0.0085 16.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KIK31860.1 - 0.0072 16.3 0.5 0.016 15.1 0.5 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KIK31860.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KIK31860.1 - 0.021 14.0 0.1 0.027 13.6 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Septin PF00735.18 KIK31860.1 - 0.024 13.9 0.4 0.096 11.9 0.4 1.9 1 1 0 1 1 1 0 Septin MCM PF00493.23 KIK31860.1 - 0.027 13.6 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain TniB PF05621.11 KIK31860.1 - 0.03 13.7 0.0 0.068 12.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein AAA_23 PF13476.6 KIK31860.1 - 0.037 14.5 2.8 0.089 13.3 2.8 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KIK31860.1 - 0.06 13.1 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIK31860.1 - 0.072 13.6 0.1 0.12 12.9 0.1 1.6 1 1 0 1 1 1 0 ABC transporter Type_III_YscX PF09474.10 KIK31860.1 - 0.14 12.5 0.0 0.31 11.3 0.0 1.6 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) DUF3882 PF07066.11 KIK31862.1 - 0.18 11.8 0.0 0.25 11.4 0.0 1.3 1 1 0 1 1 1 0 Lactococcus phage M3 protein Pkinase_Tyr PF07714.17 KIK31864.1 - 5.7e-34 117.6 0.0 9.3e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK31864.1 - 3.7e-30 105.2 0.0 5.6e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK31864.1 - 0.01 15.2 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATP-synt_DE PF00401.20 KIK31864.1 - 0.027 14.7 1.5 0.068 13.4 1.5 1.7 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain APH PF01636.23 KIK31864.1 - 0.06 13.3 0.4 0.27 11.1 0.1 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family RVT_1 PF00078.27 KIK31866.1 - 0.0092 15.5 0.0 0.0092 15.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PhaP_Bmeg PF09602.10 KIK31866.1 - 0.23 11.4 0.0 0.31 11.0 0.0 1.1 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) RT_RNaseH_2 PF17919.1 KIK31867.1 - 3e-08 33.6 0.0 3.4e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KIK31867.1 - 0.1 12.9 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Lactamase_B_2 PF12706.7 KIK31869.1 - 1.1e-06 28.4 0.2 2.7e-06 27.1 0.2 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 KIK31869.1 - 3.1e-05 24.1 0.0 5.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 KIK31869.1 - 0.022 14.8 2.0 0.098 12.7 1.9 2.0 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily RVT_1 PF00078.27 KIK31872.1 - 3.2e-05 23.6 0.0 3.6e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 KIK31873.1 - 0.00085 20.1 0.3 0.0069 17.2 0.1 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat HalOD2 PF18547.1 KIK31875.1 - 0.045 13.7 0.4 0.045 13.7 0.4 3.0 4 0 0 4 4 4 0 Halobacterial output domain 2 WD40 PF00400.32 KIK31876.1 - 3.5e-09 37.1 0.9 0.00019 22.1 0.1 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK31876.1 - 0.036 14.4 0.1 1.2 9.5 0.0 2.2 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Phage-tail_3 PF13550.6 KIK31877.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.6 2 0 0 2 2 2 0 Putative phage tail protein Rpr2 PF04032.16 KIK31878.1 - 0.093 13.0 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Helitron_like_N PF14214.6 KIK31881.1 - 9.6e-22 78.1 0.1 1.1e-21 78.0 0.1 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus zf-NF-X1 PF01422.17 KIK31882.1 - 0.0075 16.3 5.5 0.017 15.1 5.5 1.7 1 0 0 1 1 1 1 NF-X1 type zinc finger CobA_CobO_BtuR PF02572.15 KIK31882.1 - 0.018 15.3 0.0 0.028 14.7 0.0 1.3 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Mac PF12464.8 KIK31882.1 - 0.12 12.7 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 Maltose acetyltransferase Plavaka PF18759.1 KIK31884.1 - 1.5e-44 152.5 0.1 2.1e-44 152.1 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK31885.1 - 2.7e-60 204.3 0.0 3.5e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Dimer_Tnp_hAT PF05699.14 KIK31887.1 - 2.9e-13 49.4 0.1 4.1e-13 48.9 0.1 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KIK31888.1 - 0.002 18.4 0.3 0.0039 17.5 0.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4413) Tom22 PF04281.13 KIK31889.1 - 0.74 9.6 3.1 2.8 7.7 3.1 1.9 1 1 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Gyro_capsid PF04162.12 KIK31892.1 - 0.13 10.7 0.1 0.2 10.1 0.1 1.3 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) p450 PF00067.22 KIK31893.1 - 2.6e-17 62.8 0.0 3.1e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RVP_2 PF08284.11 KIK31894.1 - 7.7e-05 22.5 0.1 0.0001 22.1 0.1 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KIK31894.1 - 0.00023 21.7 0.0 0.00027 21.5 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.8 KIK31894.1 - 0.00052 19.6 0.0 0.00056 19.5 0.0 1.0 1 0 0 1 1 1 1 Ty3 transposon peptidase gag-asp_proteas PF13975.6 KIK31894.1 - 0.03 14.9 0.0 0.035 14.7 0.0 1.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease T2SSM_b PF10741.9 KIK31896.1 - 0.0094 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M subtype b DMA PF03474.14 KIK31896.1 - 0.12 12.0 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 DMRTA motif APH PF01636.23 KIK31901.1 - 0.016 15.2 0.7 0.016 15.2 0.7 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIK31901.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Herpes_UL49_5 PF05702.11 KIK31903.1 - 0.0055 16.8 0.2 0.0081 16.2 0.2 1.2 1 0 0 1 1 1 1 Herpesvirus UL49.5 envelope/tegument protein DUF1815 PF08844.10 KIK31903.1 - 0.02 14.8 0.1 0.028 14.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) PBP1_TM PF14812.6 KIK31906.1 - 0.2 12.0 1.8 0.35 11.3 1.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cut8 PF08559.10 KIK31906.1 - 0.67 9.5 4.4 0.15 11.7 0.6 1.8 2 0 0 2 2 2 0 Cut8, nuclear proteasome tether protein MOR2-PAG1_N PF14222.6 KIK31911.1 - 6.4e-42 144.2 0.0 7.7e-42 144.0 0.0 1.0 1 0 0 1 1 1 1 Cell morphogenesis N-terminal DUF3445 PF11927.8 KIK31911.1 - 0.15 11.6 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) MMR_HSR1 PF01926.23 KIK31912.1 - 0.0004 20.4 0.0 0.00063 19.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KIK31912.1 - 0.0052 16.3 0.0 0.016 14.7 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KIK31912.1 - 0.028 14.6 0.0 0.067 13.4 0.0 1.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KIK31912.1 - 0.18 11.3 0.0 6.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF4413 PF14372.6 KIK31916.1 - 0.005 17.2 0.1 0.0062 16.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) Dimer_Tnp_hAT PF05699.14 KIK31917.1 - 6.3e-15 54.7 0.2 7.7e-15 54.5 0.2 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DEAD PF00270.29 KIK31919.1 - 0.00011 22.0 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_3 PF13920.6 KIK31920.1 - 6.5e-06 25.9 3.2 1.2e-05 25.0 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ATG16 PF08614.11 KIK31920.1 - 1e-05 25.9 14.1 1e-05 25.9 14.1 2.5 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) zf-C3HC4 PF00097.25 KIK31920.1 - 1.7e-05 24.6 4.1 3.4e-05 23.6 4.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK31920.1 - 2.1e-05 24.4 4.0 4.3e-05 23.4 4.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KIK31920.1 - 6.3e-05 22.7 4.8 0.00012 21.8 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK31920.1 - 0.00015 22.0 4.2 0.00028 21.1 4.2 1.5 1 0 0 1 1 1 1 Ring finger domain ADIP PF11559.8 KIK31920.1 - 0.00029 21.0 10.7 0.00029 21.0 10.7 2.4 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding zf-C3HC4_4 PF15227.6 KIK31920.1 - 0.00064 19.8 2.6 0.0013 18.8 2.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KIK31920.1 - 0.00098 19.1 4.7 0.0019 18.1 4.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KIK31920.1 - 0.0011 18.8 4.6 0.002 18.0 4.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_5 PF17121.5 KIK31920.1 - 0.0047 16.8 3.5 0.0099 15.7 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) YabA PF06156.13 KIK31920.1 - 0.02 15.5 14.6 0.67 10.6 1.9 2.7 2 0 0 2 2 2 0 Initiation control protein YabA zf-RING_4 PF14570.6 KIK31920.1 - 0.023 14.5 3.0 0.055 13.3 3.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4201 PF13870.6 KIK31920.1 - 0.039 13.7 28.2 0.028 14.1 12.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) MscS_porin PF12795.7 KIK31920.1 - 0.076 12.6 20.8 0.04 13.5 11.8 2.4 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain zf-rbx1 PF12678.7 KIK31920.1 - 0.081 13.2 2.1 0.21 11.9 2.1 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KIK31920.1 - 0.16 12.0 0.5 0.31 11.1 0.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger ERM PF00769.19 KIK31920.1 - 0.28 10.9 41.3 1.1 9.0 41.3 2.1 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DivIVA PF05103.13 KIK31920.1 - 0.78 9.8 23.9 0.3 11.2 9.6 2.9 1 1 1 3 3 3 0 DivIVA protein Nup54 PF13874.6 KIK31920.1 - 1.8 8.7 22.8 1.5 9.0 3.3 2.7 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 Laminin_II PF06009.12 KIK31920.1 - 2 8.4 13.2 6.1 6.9 0.8 2.4 1 1 1 2 2 2 0 Laminin Domain II DUF2205 PF10224.9 KIK31920.1 - 2.5 8.2 13.3 0.13 12.3 4.3 2.6 2 0 0 2 2 2 0 Short coiled-coil protein Spc7 PF08317.11 KIK31920.1 - 3.1 6.6 28.7 17 4.2 28.6 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.6 KIK31920.1 - 3.3 7.0 34.3 0.19 11.1 11.7 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 KIK31920.1 - 4.1 7.9 38.9 0.084 13.4 14.7 3.0 2 1 1 3 3 3 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 KIK31920.1 - 4.7 7.4 35.7 31 4.8 24.9 2.7 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 BLOC1_2 PF10046.9 KIK31920.1 - 5.1 7.5 16.5 2 8.8 4.3 3.2 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.8 KIK31920.1 - 5.2 6.3 24.7 2.7 7.2 12.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Bap31_Bap29_C PF18035.1 KIK31920.1 - 5.3 7.1 15.1 3.9 7.6 9.3 2.8 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Occludin_ELL PF07303.13 KIK31920.1 - 5.8 7.7 18.0 2.4 8.9 5.2 2.7 1 1 0 2 2 2 0 Occludin homology domain E2F_CC-MB PF16421.5 KIK31920.1 - 6.8 7.1 14.2 0.36 11.2 0.2 2.9 2 2 0 2 2 2 0 E2F transcription factor CC-MB domain UvrD_C_2 PF13538.6 KIK31921.1 - 0.0024 17.7 1.5 0.02 14.7 1.5 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KIK31921.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KIK31922.1 - 6e-11 42.4 0.0 8.7e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 KIK31922.1 - 1.7e-09 37.3 0.3 9.8e-09 34.8 0.3 1.9 1 1 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 KIK31922.1 - 3.2e-08 34.0 0.1 6.9e-08 32.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK31922.1 - 0.0017 18.6 0.0 0.0054 17.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 KIK31922.1 - 0.013 15.4 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Helicase AAA_29 PF13555.6 KIK31922.1 - 0.037 13.8 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KIK31922.1 - 0.05 13.0 0.1 0.075 12.4 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KIK31922.1 - 0.051 12.9 0.0 0.085 12.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 KIK31922.1 - 0.056 13.9 0.5 0.11 13.0 0.5 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KIK31922.1 - 0.078 12.8 0.1 0.14 11.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIK31922.1 - 0.13 12.7 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KIK31922.1 - 0.14 11.8 0.1 0.31 10.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KIK31922.1 - 0.18 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_5 PF07728.14 KIK31922.1 - 0.19 11.8 0.1 0.32 11.0 0.1 1.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) PRA-PH PF01503.17 KIK31924.1 - 4.9 7.7 7.0 0.63 10.5 0.3 2.2 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase RecG_N PF17190.4 KIK31926.1 - 0.019 15.7 0.4 0.067 13.9 0.4 1.9 1 0 0 1 1 1 0 RecG N-terminal helical domain GAS PF13851.6 KIK31926.1 - 0.036 13.4 0.6 0.036 13.4 0.6 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Rad60-SLD PF11976.8 KIK31926.1 - 0.34 10.8 6.3 10 6.0 0.2 3.4 3 1 1 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like Cauli_VI PF01693.16 KIK31927.1 - 2.8e-06 27.5 0.1 4.1e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF883 PF05957.13 KIK31928.1 - 0.037 14.6 0.7 0.043 14.4 0.7 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) MscS_TM PF12794.7 KIK31928.1 - 0.061 12.2 1.2 0.064 12.1 1.2 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 ZapB PF06005.12 KIK31932.1 - 0.061 13.8 0.2 0.11 12.9 0.2 1.4 1 0 0 1 1 1 0 Cell division protein ZapB betaPIX_CC PF16523.5 KIK31932.1 - 0.083 12.7 0.8 0.22 11.3 0.8 1.8 1 1 0 1 1 1 0 betaPIX coiled coil DivIC PF04977.15 KIK31932.1 - 0.12 12.2 2.6 0.26 11.1 2.6 1.6 1 0 0 1 1 1 0 Septum formation initiator TFIIS_M PF07500.14 KIK31933.1 - 7e-15 55.5 0.4 8.2e-15 55.3 0.4 1.0 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Glyco_hydro_3 PF00933.21 KIK31938.1 - 2.5e-23 82.9 0.0 3.5e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain MULE PF10551.9 KIK31939.1 - 0.00086 19.7 0.2 0.0038 17.6 0.2 2.1 1 1 0 1 1 1 1 MULE transposase domain ABC_tran PF00005.27 KIK31941.1 - 1.3e-07 32.2 0.0 2.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_tran_Xtn PF12848.7 KIK31941.1 - 0.00016 21.7 3.0 0.00016 21.7 3.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 KIK31941.1 - 0.0022 17.7 0.2 0.0042 16.8 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KIK31941.1 - 0.019 15.0 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 KIK31941.1 - 0.11 13.0 0.3 0.65 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain PAS_10 PF13596.6 KIK31942.1 - 0.087 13.4 0.0 2.3 8.8 0.0 2.4 2 0 0 2 2 2 0 PAS domain Nop14 PF04147.12 KIK31943.1 - 0.038 12.2 6.4 0.045 12.0 6.4 1.0 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 KIK31943.1 - 0.25 11.3 2.8 0.43 10.6 2.8 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 KIK31943.1 - 0.64 9.3 6.3 0.82 8.9 6.3 1.1 1 0 0 1 1 1 0 NOA36 protein Astro_capsid_p PF12226.8 KIK31943.1 - 0.66 9.1 9.3 0.96 8.5 9.3 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Sporozoite_P67 PF05642.11 KIK31943.1 - 4.4 5.3 9.8 5.8 4.9 9.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 KIK31943.1 - 6.5 4.7 12.9 8.2 4.4 12.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Plavaka PF18759.1 KIK31945.1 - 1.5e-37 129.6 0.0 2.1e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase CxC5 PF18718.1 KIK31947.1 - 3.4e-31 107.7 6.2 4.9e-31 107.2 6.2 1.2 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases Alpha_kinase PF02816.18 KIK31948.1 - 1.8e-16 60.8 0.6 2.1e-16 60.6 0.6 1.0 1 0 0 1 1 1 1 Alpha-kinase family Lactamase_B PF00753.27 KIK31949.1 - 0.098 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Mn_catalase PF05067.12 KIK31949.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Manganese containing catalase Retrotran_gag_2 PF14223.6 KIK31949.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Zn_Tnp_IS1595 PF12760.7 KIK31949.1 - 0.26 11.3 3.4 0.62 10.1 3.4 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Phage_min_cap2 PF06152.11 KIK31950.1 - 1.2 7.9 3.3 2 7.3 3.3 1.3 1 0 0 1 1 1 0 Phage minor capsid protein 2 Exonuc_VII_L PF02601.15 KIK31951.1 - 0.58 9.7 17.6 0.68 9.5 7.0 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit Thiamine_BP PF01910.17 KIK31955.1 - 7.8e-06 25.7 0.0 9.8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Thiamine-binding protein zf-CCHC PF00098.23 KIK31957.1 - 2.6e-06 27.3 3.8 4e-06 26.7 3.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KIK31957.1 - 0.0014 18.4 0.9 0.0025 17.6 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 KIK31957.1 - 0.81 9.5 4.1 1.3 8.8 4.1 1.3 1 0 0 1 1 1 0 Zinc knuckle Mucin PF01456.17 KIK31960.1 - 4.5 7.3 12.5 6.9 6.7 12.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Aminotran_3 PF00202.21 KIK31961.1 - 0.11 11.1 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Big_3_3 PF13750.6 KIK31963.1 - 0.066 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Taq-exonuc PF09281.10 KIK31964.1 - 0.1 12.6 0.1 0.28 11.2 0.1 1.7 1 0 0 1 1 1 0 Taq polymerase, exonuclease Tim17 PF02466.19 KIK31965.1 - 3e-33 114.5 7.8 3.6e-33 114.3 7.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Lentiviral_Tat PF02998.14 KIK31965.1 - 0.17 12.0 0.0 1.2 9.2 0.0 2.0 2 0 0 2 2 2 0 Lentiviral Tat protein CaM-KIIN PF15170.6 KIK31967.1 - 0.054 13.6 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Calcium/calmodulin-dependent protein kinase II inhibitor zf-BED PF02892.15 KIK31967.1 - 0.26 11.3 3.3 0.61 10.2 3.3 1.6 1 0 0 1 1 1 0 BED zinc finger Trypan_PARP PF05887.11 KIK31967.1 - 4.3 7.3 10.6 5.9 6.9 9.9 1.5 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Prefoldin PF02996.17 KIK31971.1 - 1.4e-11 44.3 0.0 1.6e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit FGGY_N PF00370.21 KIK31972.1 - 0.058 13.0 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain ABATE PF07336.11 KIK31972.1 - 0.44 11.2 2.3 2.4 8.8 0.3 2.2 2 0 0 2 2 2 0 Putative stress-induced transcription regulator Arm PF00514.23 KIK31973.1 - 5.1e-59 194.6 10.7 1.1e-13 50.6 0.1 7.0 7 0 0 7 7 7 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KIK31973.1 - 7.3e-17 61.5 0.4 1.8e-05 25.1 0.0 4.2 3 1 1 4 4 4 3 HEAT-like repeat HEAT PF02985.22 KIK31973.1 - 7.5e-10 38.2 0.1 0.039 14.2 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KIK31973.1 - 4.4e-09 36.6 0.0 0.0018 18.6 0.0 4.1 1 1 2 4 4 4 3 HEAT repeats Adaptin_N PF01602.20 KIK31973.1 - 4e-06 25.7 0.0 0.00013 20.7 0.0 2.2 1 1 0 1 1 1 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 KIK31973.1 - 0.043 13.9 0.0 0.37 10.9 0.0 2.3 2 1 0 2 2 2 0 V-ATPase subunit H Atx10homo_assoc PF09759.9 KIK31973.1 - 0.12 12.4 0.0 26 4.9 0.0 2.9 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Glyco_hydro_3_C PF01915.22 KIK31974.1 - 1e-30 107.2 0.1 1.1e-30 107.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Swm2 PF17083.5 KIK31975.1 - 0.0097 15.9 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 1 Nucleolar protein Swm2 DUF2116 PF09889.9 KIK31978.1 - 9 6.4 7.1 0.94 9.5 0.8 2.1 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Dimer_Tnp_hAT PF05699.14 KIK31980.1 - 2.2e-10 40.2 0.3 2.9e-10 39.8 0.3 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KIK31981.1 - 0.001 19.4 0.1 0.0011 19.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) Pes-10 PF07149.11 KIK31982.1 - 0.32 10.0 5.1 0.33 10.0 5.1 1.1 1 0 0 1 1 1 0 Pes-10 KDZ PF18758.1 KIK31983.1 - 5.2e-50 170.1 0.0 8.8e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CNH PF00780.22 KIK31986.1 - 3.4e-09 36.7 0.0 3.8e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 CNH domain Chaperone_III PF07824.12 KIK31986.1 - 0.13 12.5 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Type III secretion chaperone domain Polysacc_synt_4 PF04669.13 KIK31989.1 - 0.013 15.0 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis Apolipoprotein PF01442.18 KIK31990.1 - 0.083 12.8 0.9 0.22 11.4 0.9 1.7 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF5024 PF16427.5 KIK31990.1 - 0.098 13.0 4.2 0.26 11.6 4.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5024) HMG_box PF00505.19 KIK31990.1 - 2.5 8.6 13.5 0.92 10.0 4.4 3.4 3 1 1 4 4 4 0 HMG (high mobility group) box SLC12 PF03522.15 KIK31991.1 - 0.0083 15.2 4.6 0.0094 15.0 4.6 1.0 1 0 0 1 1 1 1 Solute carrier family 12 FANCI_HD2 PF14680.6 KIK31991.1 - 0.14 11.4 1.3 0.17 11.1 1.3 1.2 1 0 0 1 1 1 0 FANCI helical domain 2 AAA_11 PF13086.6 KIK31991.1 - 0.17 11.7 8.7 0.2 11.4 8.7 1.2 1 0 0 1 1 1 0 AAA domain DDRGK PF09756.9 KIK31991.1 - 0.38 10.3 22.5 0.43 10.1 22.5 1.2 1 0 0 1 1 1 0 DDRGK domain eIF3_subunit PF08597.10 KIK31991.1 - 0.59 10.0 16.7 0.69 9.8 16.7 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4778 PF16008.5 KIK31991.1 - 0.63 10.1 9.8 0.66 10.0 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) FAM76 PF16046.5 KIK31991.1 - 0.75 9.1 6.7 0.92 8.8 6.7 1.1 1 0 0 1 1 1 0 FAM76 protein CDC45 PF02724.14 KIK31991.1 - 1.2 7.3 15.9 1.4 7.1 15.9 1.1 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.6 KIK31991.1 - 1.7 8.8 8.4 1.9 8.6 8.4 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3450 PF11932.8 KIK31991.1 - 1.7 7.9 13.6 2.1 7.6 13.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) WDCP PF15390.6 KIK31991.1 - 2.1 6.6 4.9 2.3 6.5 4.9 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family APG6_N PF17675.1 KIK31991.1 - 2.4 8.7 20.8 3.2 8.3 20.8 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4407 PF14362.6 KIK31991.1 - 3.1 7.1 12.1 3.4 6.9 12.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) U79_P34 PF03064.16 KIK31991.1 - 3.7 6.8 20.5 5.1 6.4 20.5 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 MDM10 PF12519.8 KIK31991.1 - 4.6 6.0 8.5 5.3 5.8 8.5 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Borrelia_P83 PF05262.11 KIK31991.1 - 5.1 5.5 12.3 5.1 5.5 12.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2514 PF10721.9 KIK31991.1 - 5.2 7.1 18.6 6.6 6.7 18.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) GBP_C PF02841.14 KIK31991.1 - 5.4 6.3 14.7 6.4 6.1 14.7 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain RNA_pol_Rpc4 PF05132.14 KIK31991.1 - 6.3 7.2 6.6 9 6.7 6.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Asp-B-Hydro_N PF05279.11 KIK31991.1 - 8.8 6.3 15.8 9.8 6.2 15.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Nup84_Nup100 PF04121.13 KIK31992.1 - 7.7e-08 30.9 0.0 8.5e-08 30.8 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 ImpE PF07024.13 KIK31992.1 - 0.06 13.4 0.0 0.065 13.3 0.0 1.1 1 0 0 1 1 1 0 ImpE protein Plavaka PF18759.1 KIK31994.1 - 2.6e-15 56.5 0.0 2.7e-15 56.4 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK31995.1 - 9.7e-61 205.8 0.1 1.3e-60 205.4 0.1 1.1 1 0 0 1 1 1 1 Plavaka transposase RecO_C PF02565.15 KIK31996.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.5 2 0 0 2 2 2 0 Recombination protein O C terminal Transposase_21 PF02992.14 KIK31997.1 - 0.0074 15.6 0.0 0.35 10.1 0.0 2.2 2 0 0 2 2 2 2 Transposase family tnp2 WGR PF05406.15 KIK31998.1 - 0.0083 16.2 0.1 0.014 15.5 0.1 1.3 1 0 0 1 1 1 1 WGR domain MCR_alpha_N PF02745.15 KIK31999.1 - 0.093 12.1 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain Phage_integrase PF00589.22 KIK32000.1 - 0.0013 18.5 0.0 0.0062 16.3 0.0 1.9 2 0 0 2 2 2 1 Phage integrase family ATPase-cat_bd PF12156.8 KIK32003.1 - 0.39 11.5 1.6 0.83 10.4 1.6 1.5 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase Myb_DNA-bind_3 PF12776.7 KIK32004.1 - 0.0024 18.8 0.2 0.0036 18.3 0.2 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KIK32004.1 - 0.011 16.1 0.0 0.19 12.1 0.0 2.1 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Toxin_R_bind_N PF07953.12 KIK32004.1 - 0.035 13.8 0.3 0.038 13.7 0.3 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, N-terminal receptor binding EST1 PF10374.9 KIK32004.1 - 0.11 13.1 0.2 0.13 12.9 0.2 1.1 1 0 0 1 1 1 0 Telomerase activating protein Est1 MMR_HSR1 PF01926.23 KIK32007.1 - 0.00059 19.9 0.0 0.00084 19.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KIK32007.1 - 0.0045 16.5 0.0 0.014 14.8 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KIK32007.1 - 0.019 15.2 0.0 0.043 14.0 0.0 1.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KIK32007.1 - 0.11 12.0 0.0 5.6 6.5 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KIK32007.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B CTD_bind PF04818.13 KIK32008.1 - 0.12 13.2 0.4 1.6 9.6 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase II-binding domain. DUF429 PF04250.13 KIK32010.1 - 0.029 14.2 0.0 0.032 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF429) HTH_32 PF13565.6 KIK32011.1 - 0.0012 19.4 0.0 0.0018 18.9 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_33 PF13592.6 KIK32011.1 - 0.086 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix NACHT PF05729.12 KIK32014.1 - 5e-05 23.3 0.2 5e-05 23.3 0.2 1.0 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 KIK32014.1 - 0.011 15.0 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain Ribosomal_S19e PF01090.19 KIK32016.1 - 0.0052 16.5 0.1 0.013 15.2 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S19e Plectin PF00681.20 KIK32016.1 - 0.072 13.0 1.3 15 5.5 0.1 3.0 3 0 0 3 3 3 0 Plectin repeat PDE6_gamma PF04868.12 KIK32021.1 - 0.0029 17.8 0.4 0.0034 17.6 0.4 1.1 1 0 0 1 1 1 1 Retinal cGMP phosphodiesterase, gamma subunit Dor1 PF04124.12 KIK32030.1 - 0.15 10.8 0.0 0.15 10.8 0.0 1.0 1 0 0 1 1 1 0 Dor1-like family KDZ PF18758.1 KIK32035.1 - 2.6e-25 89.4 1.7 8e-24 84.5 0.7 2.1 2 0 0 2 2 2 2 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK32035.1 - 0.0021 18.2 0.0 0.0049 17.0 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIK32036.1 - 1.5e-48 165.3 0.7 1.7e-48 165.2 0.7 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Peptidase_M3_N PF08439.10 KIK32037.1 - 0.066 13.5 0.5 0.67 10.3 0.2 2.4 2 0 0 2 2 2 0 Oligopeptidase F HMG_box PF00505.19 KIK32038.1 - 0.11 13.0 2.6 0.2 12.1 2.6 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box UPF0449 PF15136.6 KIK32038.1 - 0.79 10.2 3.7 0.58 10.7 0.6 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Spt5_N PF11942.8 KIK32038.1 - 9.3 7.3 10.2 4.5 8.3 3.5 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DOCK_N PF16172.5 KIK32039.1 - 3.4e-29 101.9 0.0 6e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 DOCK N-terminus RVT_1 PF00078.27 KIK32040.1 - 2.5e-06 27.2 0.0 2.6e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ANAPC4_WD40 PF12894.7 KIK32041.1 - 1.9e-06 28.1 0.0 0.014 15.7 0.1 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK32041.1 - 0.0021 18.8 4.0 2.4 9.1 0.1 5.6 6 0 0 6 6 6 1 WD domain, G-beta repeat RCC1_2 PF13540.6 KIK32041.1 - 0.29 11.0 4.9 0.26 11.2 0.2 3.0 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat zf-Di19 PF05605.12 KIK32042.1 - 0.31 11.4 4.0 0.5 10.7 0.1 2.7 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding BAR_3_WASP_bdg PF10456.9 KIK32043.1 - 0.25 10.7 0.0 0.33 10.4 0.0 1.1 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein Transposase_21 PF02992.14 KIK32044.1 - 6.1e-10 38.7 0.1 7.6e-10 38.4 0.1 1.2 1 0 0 1 1 1 1 Transposase family tnp2 Plavaka PF18759.1 KIK32044.1 - 0.0035 16.6 0.6 0.0042 16.3 0.6 1.1 1 0 0 1 1 1 1 Plavaka transposase TPR_10 PF13374.6 KIK32046.1 - 1.6e-11 43.7 9.5 0.00029 20.6 0.1 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK32046.1 - 3.5e-08 33.6 10.7 0.024 14.9 1.1 6.2 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIK32046.1 - 8.9e-07 28.5 3.3 0.11 12.4 0.2 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK32046.1 - 2.7e-06 27.1 5.2 0.19 11.9 0.6 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK32046.1 - 6.8e-06 25.7 3.7 0.075 12.7 0.2 4.0 4 0 0 4 4 4 2 TPR repeat TPR_8 PF13181.6 KIK32046.1 - 0.00063 19.8 0.0 1.7 9.0 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK32046.1 - 0.00068 20.3 12.7 0.57 11.1 0.1 5.9 5 1 1 6 6 5 2 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 KIK32046.1 - 0.018 15.1 0.9 10 6.3 0.0 3.5 3 0 0 3 3 3 0 Exonuclease VII small subunit TPR_16 PF13432.6 KIK32046.1 - 0.094 13.4 8.7 0.063 13.9 2.6 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat FRB_dom PF08771.11 KIK32046.1 - 0.14 12.6 0.0 1.2e+02 3.2 0.0 4.0 4 0 0 4 4 4 0 FKBP12-rapamycin binding domain TPR_7 PF13176.6 KIK32046.1 - 0.18 11.9 3.0 2 8.6 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK32046.1 - 0.63 10.6 4.5 24 5.5 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Phage_integrase PF00589.22 KIK32047.1 - 0.15 11.8 0.0 0.15 11.8 0.0 1.0 1 0 0 1 1 1 0 Phage integrase family Transposase_21 PF02992.14 KIK32051.1 - 0.00048 19.4 0.0 0.00081 18.7 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 ATG22 PF11700.8 KIK32053.1 - 1.2e-79 268.1 28.4 1.4e-79 267.9 28.4 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like WD40 PF00400.32 KIK32054.1 - 1.4e-16 60.6 5.2 2.5e-07 31.3 0.8 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.8 KIK32054.1 - 0.0036 16.0 0.4 0.38 9.3 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PD40 PF07676.12 KIK32054.1 - 0.0048 16.8 0.0 0.021 14.8 0.0 2.1 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat MBOAT_2 PF13813.6 KIK32056.1 - 1.7e-14 53.8 4.3 1.7e-14 53.8 4.3 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family EMP24_GP25L PF01105.24 KIK32058.1 - 0.00073 19.5 0.6 0.00098 19.1 0.6 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Z1 PF10593.9 KIK32058.1 - 0.0019 17.7 0.1 0.0022 17.5 0.1 1.0 1 0 0 1 1 1 1 Z1 domain DUF4201 PF13870.6 KIK32058.1 - 0.0082 15.9 0.6 0.011 15.5 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Glyco_transf_18 PF15024.6 KIK32058.1 - 0.038 12.6 0.4 0.044 12.4 0.4 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 18 DUF2096 PF09869.9 KIK32058.1 - 0.094 12.8 0.3 0.15 12.1 0.3 1.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) CENP-Q PF13094.6 KIK32058.1 - 1.2 9.3 7.6 0.62 10.2 4.4 1.8 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit MFS_1 PF07690.16 KIK32060.1 - 1e-08 34.5 2.3 1.1e-08 34.4 2.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK32060.1 - 0.00067 18.6 2.1 0.00067 18.6 2.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KIK32060.1 - 0.003 16.0 0.2 0.0033 15.9 0.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) WD40 PF00400.32 KIK32064.1 - 5.9e-51 169.3 34.0 4.8e-10 39.9 0.8 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32064.1 - 4.6e-22 78.1 6.7 5.5e-05 23.4 0.0 6.9 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK32064.1 - 1.2e-08 34.4 0.7 3 6.7 0.1 5.9 1 1 3 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK32064.1 - 6.2e-08 31.7 3.0 0.015 14.0 0.6 4.6 3 1 2 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK32064.1 - 1.8e-05 24.2 0.0 0.54 9.5 0.0 3.5 3 1 1 4 4 4 2 WD40-like domain PD40 PF07676.12 KIK32064.1 - 0.00028 20.7 0.1 22 5.1 0.0 4.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF5570 PF17731.1 KIK32064.1 - 0.0048 17.0 1.7 0.11 12.6 0.1 3.2 2 1 1 3 3 3 1 Family of unknown function (DUF5570) Nbas_N PF15492.6 KIK32064.1 - 0.0048 16.3 0.8 0.31 10.3 0.1 3.3 2 2 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 KIK32064.1 - 0.024 13.4 0.9 6.5 5.4 0.1 3.2 2 2 2 4 4 4 0 Nup133 N terminal like TonB_2 PF13103.6 KIK32064.1 - 0.041 14.1 0.9 14 6.0 0.1 3.2 3 1 0 3 3 3 0 TonB C terminal zf_UBZ PF18439.1 KIK32068.1 - 0.1 12.2 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger DUF782 PF05614.11 KIK32068.1 - 0.17 12.3 0.4 26 5.3 0.0 2.7 1 1 1 2 2 2 0 Circovirus protein of unknown function (DUF782) Dimer_Tnp_hAT PF05699.14 KIK32072.1 - 1.9e-13 50.0 0.0 1.9e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KIK32073.1 - 0.054 13.9 0.1 0.076 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Gal11_ABD1 PF18535.1 KIK32077.1 - 0.066 13.3 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 Gal11 activator-binding domain (ABD1) Phage_integrase PF00589.22 KIK32078.1 - 0.038 13.8 0.0 0.19 11.5 0.0 2.2 2 1 0 2 2 2 0 Phage integrase family DUF3435 PF11917.8 KIK32078.1 - 0.061 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Response_reg PF00072.24 KIK32079.1 - 7.7e-09 35.7 0.0 8.2e-09 35.6 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain FSA_C PF10479.9 KIK32080.1 - 8.6 4.4 12.7 9.8 4.2 12.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus ATG16 PF08614.11 KIK32081.1 - 0.00015 22.0 0.2 0.00018 21.8 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Uso1_p115_C PF04871.13 KIK32081.1 - 0.0069 16.8 1.1 0.0086 16.4 1.1 1.1 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Mod_r PF07200.13 KIK32081.1 - 0.016 15.3 1.2 0.021 14.9 1.2 1.1 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein YwqJ-deaminase PF14431.6 KIK32081.1 - 0.03 14.5 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 YwqJ-like deaminase AIP3 PF03915.13 KIK32081.1 - 0.034 13.3 0.9 0.036 13.2 0.9 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 Snapin_Pallidin PF14712.6 KIK32081.1 - 0.041 14.3 2.0 0.089 13.2 2.0 1.6 1 1 0 1 1 1 0 Snapin/Pallidin DUF773 PF05600.12 KIK32081.1 - 0.06 12.1 1.1 0.069 11.9 1.1 1.0 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 IL2 PF00715.17 KIK32081.1 - 0.083 12.8 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Interleukin 2 Fez1 PF06818.15 KIK32081.1 - 0.1 13.0 0.7 0.12 12.8 0.7 1.1 1 0 0 1 1 1 0 Fez1 TolA_bind_tri PF16331.5 KIK32081.1 - 0.12 12.5 2.2 0.23 11.6 2.1 1.5 1 1 0 1 1 1 0 TolA binding protein trimerisation TMPIT PF07851.13 KIK32081.1 - 0.13 11.5 0.4 0.16 11.2 0.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein XhlA PF10779.9 KIK32081.1 - 0.17 12.1 1.8 0.59 10.4 0.7 2.0 2 0 0 2 2 2 0 Haemolysin XhlA Baculo_PEP_C PF04513.12 KIK32081.1 - 0.18 11.9 3.2 0.3 11.1 3.2 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FAM76 PF16046.5 KIK32081.1 - 0.18 11.1 0.6 0.21 10.9 0.6 1.0 1 0 0 1 1 1 0 FAM76 protein Cupin_6 PF12852.7 KIK32082.1 - 0.0053 16.5 0.1 0.27 10.9 0.0 2.2 2 0 0 2 2 2 1 Cupin Cupin_4 PF08007.12 KIK32082.1 - 0.0085 15.6 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KIK32082.1 - 0.052 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase Cupin_2 PF07883.11 KIK32082.1 - 0.093 12.5 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Cupin domain Pkinase_Tyr PF07714.17 KIK32083.1 - 1.6e-24 86.6 0.0 2e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK32083.1 - 3e-23 82.5 0.0 3.9e-23 82.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK32083.1 - 0.00013 20.9 0.0 0.00016 20.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK32083.1 - 0.0034 17.4 0.2 0.0058 16.6 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KIK32083.1 - 0.041 13.2 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIK32083.1 - 0.041 13.5 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family HTH_49 PF18010.1 KIK32086.1 - 0.069 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Cry35Ab1 HTH C-terminal domain Plavaka PF18759.1 KIK32089.1 - 0.0003 20.1 0.0 0.00045 19.5 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase CBM_5_12_2 PF14600.6 KIK32090.1 - 0.046 13.7 0.1 0.098 12.6 0.1 1.5 1 0 0 1 1 1 0 Cellulose-binding domain Auxin_resp PF06507.13 KIK32090.1 - 0.27 11.5 0.1 0.27 11.5 0.1 2.1 2 1 0 2 2 2 0 Auxin response factor PNMA PF14893.6 KIK32092.1 - 0.0028 17.1 0.1 0.0032 16.9 0.1 1.1 1 0 0 1 1 1 1 PNMA Retrotrans_gag PF03732.17 KIK32092.1 - 0.013 15.8 3.6 0.027 14.7 1.1 2.5 1 1 3 4 4 4 0 Retrotransposon gag protein CNH PF00780.22 KIK32094.1 - 0.0013 18.4 0.0 0.042 13.4 0.0 2.2 2 0 0 2 2 2 2 CNH domain Fn3-like PF14310.6 KIK32095.1 - 1.9e-23 82.4 0.2 7.8e-23 80.4 0.2 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain DUF11 PF01345.18 KIK32095.1 - 0.2 12.0 2.2 0.8 10.1 2.2 1.9 1 1 0 1 1 1 0 Domain of unknown function DUF11 DUF4400 PF14348.6 KIK32096.1 - 0.027 14.0 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Phe_hydrox_dim PF07976.12 KIK32101.1 - 0.16 12.0 0.0 0.43 10.6 0.0 1.7 1 0 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain rve PF00665.26 KIK32104.1 - 0.0057 16.8 0.0 0.014 15.5 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain Pkinase_fungal PF17667.1 KIK32105.1 - 4.6e-07 29.0 0.3 8.5e-07 28.1 0.3 1.4 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK32105.1 - 0.00022 21.2 0.4 0.00027 21.0 0.4 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK32105.1 - 0.0041 16.7 0.1 0.0047 16.5 0.1 1.1 1 0 0 1 1 1 1 RIO1 family WD40 PF00400.32 KIK32106.1 - 2.7e-08 34.3 6.3 0.039 14.8 0.1 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32106.1 - 9.1e-06 25.9 0.0 0.18 12.1 0.0 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KIK32106.1 - 0.006 17.0 0.2 2.4 8.8 0.0 3.5 3 0 0 3 3 3 1 PQQ-like domain BBS2_Mid PF14783.6 KIK32106.1 - 0.17 12.0 0.1 1.5 8.9 0.0 2.6 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Alpha-amylase PF00128.24 KIK32107.1 - 9.9e-05 22.0 0.2 0.022 14.3 0.0 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain DUF5115 PF17142.4 KIK32107.1 - 0.015 15.0 0.0 0.19 11.4 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5115) zf-CCHC_4 PF14392.6 KIK32109.1 - 0.031 14.0 4.7 0.074 12.8 4.7 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 KIK32109.1 - 1.1 9.4 10.3 1.6 9.0 4.5 2.8 2 0 0 2 2 2 0 Zinc knuckle WD40 PF00400.32 KIK32110.1 - 2.5e-36 123.1 18.5 1.3e-07 32.2 0.6 7.1 6 1 1 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32110.1 - 1.4e-13 50.9 0.1 0.0088 16.3 0.0 5.5 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK32110.1 - 3e-06 27.3 0.0 0.012 15.5 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK32110.1 - 5.4e-06 25.6 0.3 0.022 13.7 0.0 3.8 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK32110.1 - 0.0012 18.7 0.1 7.8 6.6 0.0 4.4 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 KIK32110.1 - 0.018 13.8 0.3 0.089 11.5 0.1 2.1 2 1 1 3 3 3 0 Nup133 N terminal like GCP_N_terminal PF17681.1 KIK32114.1 - 3.4e-24 86.0 0.0 7.8e-23 81.6 0.0 2.0 1 1 1 2 2 2 2 Gamma tubulin complex component N-terminal HTH_23 PF13384.6 KIK32116.1 - 6.9e-06 25.7 0.0 7.3e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 KIK32116.1 - 0.0025 17.8 0.0 0.0033 17.4 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.15 KIK32116.1 - 0.0084 16.2 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 KIK32116.1 - 0.011 15.9 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KIK32116.1 - 0.014 15.1 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.6 KIK32116.1 - 0.074 12.8 0.0 0.091 12.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Terminase_5 PF06056.12 KIK32116.1 - 0.09 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) DDE_3 PF13358.6 KIK32117.1 - 0.00024 20.9 0.0 0.00028 20.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HSP70 PF00012.20 KIK32118.1 - 0.00018 19.8 0.0 0.00027 19.3 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein NDC10_II PF16787.5 KIK32123.1 - 6.4e-11 41.9 0.0 7.7e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 DUF1670 PF07900.11 KIK32124.1 - 0.03 13.7 0.0 0.035 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1670) DUF5082 PF16888.5 KIK32124.1 - 0.036 14.4 0.5 0.036 14.4 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DUF5086 PF16985.5 KIK32124.1 - 0.059 13.3 1.0 0.091 12.7 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5086) DBD_Tnp_Mut PF03108.15 KIK32124.1 - 0.061 13.3 2.4 0.12 12.4 2.3 1.6 1 1 0 1 1 1 0 MuDR family transposase Pkinase_Tyr PF07714.17 KIK32126.1 - 7.2e-30 104.1 0.0 8.2e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK32126.1 - 1.6e-22 80.2 0.0 1.9e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIK32126.1 - 0.19 11.3 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Plavaka PF18759.1 KIK32128.1 - 3.1e-42 144.9 0.0 4.9e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase XPB_DRD PF18458.1 KIK32128.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Xeroderma pigmentosum group B helicase damage recognition domain WD40 PF00400.32 KIK32129.1 - 1.4e-06 28.9 1.2 0.0058 17.5 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KIK32129.1 - 0.018 14.0 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Pertussis_S2S3 PF02918.15 KIK32129.1 - 0.089 12.7 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain tRNA-synt_His PF13393.6 KIK32130.1 - 7.8e-22 77.9 0.0 4.3e-21 75.5 0.0 1.9 1 1 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 KIK32130.1 - 0.048 13.6 0.0 0.3 11.0 0.0 2.2 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) NTS_2 PF15448.6 KIK32130.1 - 0.14 12.6 0.1 0.32 11.4 0.1 1.6 1 0 0 1 1 1 0 N-terminal segments of P. falciparum erythrocyte membrane protein Tfb2_C PF18307.1 KIK32131.1 - 0.098 13.1 0.8 0.29 11.6 0.8 1.8 1 0 0 1 1 1 0 Transcription factor Tfb2 (p52) C-terminal domain DDE_1 PF03184.19 KIK32132.1 - 4.4e-25 88.3 0.0 6.1e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KIK32132.1 - 7.8e-08 32.2 0.2 3.7e-06 26.8 0.2 2.3 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF3656 PF12392.8 KIK32132.1 - 0.0023 18.5 0.0 0.005 17.5 0.0 1.6 2 0 0 2 2 2 1 Collagenase HTH_Tnp_Tc5 PF03221.16 KIK32133.1 - 1e-06 28.6 0.0 2.3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain RVT_1 PF00078.27 KIK32136.1 - 0.011 15.3 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_16 PF13191.6 KIK32138.1 - 5.5e-10 39.9 0.0 1.4e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK32138.1 - 5.2e-05 23.3 0.0 0.00011 22.2 0.0 1.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NACHT PF05729.12 KIK32138.1 - 5.4e-05 23.2 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain APS_kinase PF01583.20 KIK32138.1 - 0.0013 18.6 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.29 KIK32138.1 - 0.0043 17.5 0.1 0.017 15.6 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK32138.1 - 0.009 16.4 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Parvo_NS1 PF01057.17 KIK32138.1 - 0.021 13.9 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 KIK32138.1 - 0.027 13.7 0.0 0.085 12.0 0.0 2.0 1 1 0 1 1 1 0 NB-ARC domain ApoLp-III PF07464.11 KIK32138.1 - 0.062 13.4 0.5 0.51 10.4 0.1 2.5 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) AAA_22 PF13401.6 KIK32138.1 - 0.093 13.0 0.3 2.6 8.3 0.0 2.7 1 1 1 2 2 2 0 AAA domain PhoU PF01895.19 KIK32138.1 - 0.1 13.0 2.1 0.22 12.0 0.1 2.4 3 0 0 3 3 3 0 PhoU domain AAA_18 PF13238.6 KIK32138.1 - 0.11 13.1 0.0 0.75 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Jnk-SapK_ap_N PF09744.9 KIK32138.1 - 4.2 7.6 5.1 22 5.3 0.2 3.2 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 RdRP PF05183.12 KIK32141.1 - 5.9e-76 256.4 0.0 3.9e-35 121.6 0.0 3.1 2 1 1 3 3 3 3 RNA dependent RNA polymerase AAA_16 PF13191.6 KIK32142.1 - 2.8e-06 27.8 0.2 1.1e-05 25.9 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KIK32142.1 - 9e-06 25.7 0.0 2.5e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 KIK32142.1 - 0.00055 19.9 0.0 0.0015 18.5 0.0 1.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 KIK32142.1 - 0.0043 17.0 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain Parvo_NS1 PF01057.17 KIK32142.1 - 0.0077 15.3 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA PF00004.29 KIK32142.1 - 0.01 16.3 0.0 0.037 14.4 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_PrkA PF08298.11 KIK32142.1 - 0.019 13.9 0.0 0.037 12.9 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain RNA_helicase PF00910.22 KIK32142.1 - 0.041 14.3 0.0 0.13 12.7 0.0 1.8 2 0 0 2 2 1 0 RNA helicase PhoU PF01895.19 KIK32142.1 - 0.064 13.7 1.1 0.54 10.8 0.1 2.6 2 0 0 2 2 2 0 PhoU domain AAA_22 PF13401.6 KIK32142.1 - 0.067 13.5 0.0 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KIK32142.1 - 0.074 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 KIK32142.1 - 0.12 11.6 0.0 0.26 10.4 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain RhoGEF PF00621.20 KIK32142.1 - 0.52 10.5 2.6 1.8 8.8 1.7 2.2 2 1 1 3 3 3 0 RhoGEF domain Baculo_PEP_C PF04513.12 KIK32145.1 - 3e-06 27.3 8.5 4e-05 23.7 5.8 2.1 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus TolA_bind_tri PF16331.5 KIK32145.1 - 0.0017 18.4 5.3 0.058 13.5 1.0 3.0 2 1 1 3 3 3 1 TolA binding protein trimerisation FH2 PF02181.23 KIK32145.1 - 0.0061 15.7 1.9 0.22 10.6 0.1 2.1 1 1 1 2 2 2 1 Formin Homology 2 Domain Apolipoprotein PF01442.18 KIK32145.1 - 0.0097 15.8 4.2 0.014 15.3 4.2 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain MPS2 PF17060.5 KIK32145.1 - 0.011 15.0 0.8 0.017 14.4 0.8 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF713 PF05218.14 KIK32145.1 - 0.015 15.0 0.1 0.16 11.7 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF713) DUF1664 PF07889.12 KIK32145.1 - 0.018 15.1 3.7 0.1 12.6 1.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HIP1_clath_bdg PF16515.5 KIK32145.1 - 0.018 15.6 3.7 0.026 15.1 2.7 1.9 2 1 0 2 2 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 OmpH PF03938.14 KIK32145.1 - 0.018 15.4 0.1 0.031 14.6 0.1 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Filament PF00038.21 KIK32145.1 - 0.019 14.6 2.7 0.022 14.3 2.7 1.1 1 0 0 1 1 1 0 Intermediate filament protein End3 PF12761.7 KIK32145.1 - 0.021 15.0 6.5 1.7 8.8 1.6 2.4 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Golgin_A5 PF09787.9 KIK32145.1 - 0.025 14.1 2.0 0.035 13.6 2.0 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 FUSC PF04632.12 KIK32145.1 - 0.033 12.7 1.9 0.039 12.5 1.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1640 PF07798.11 KIK32145.1 - 0.035 14.2 4.9 0.2 11.7 2.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Spc7 PF08317.11 KIK32145.1 - 0.053 12.4 3.2 0.35 9.7 0.5 1.8 1 1 0 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.12 KIK32145.1 - 0.056 13.9 13.2 0.11 13.0 2.3 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Myosin_tail_1 PF01576.19 KIK32145.1 - 0.067 11.0 2.3 0.088 10.6 2.3 1.0 1 0 0 1 1 1 0 Myosin tail CENP-F_leu_zip PF10473.9 KIK32145.1 - 0.071 13.1 1.7 1.1 9.3 0.4 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 KIK32145.1 - 0.073 12.7 2.3 0.29 10.8 0.7 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease ACCA PF03255.14 KIK32145.1 - 0.09 12.6 0.6 7.7 6.4 0.2 2.4 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Rootletin PF15035.6 KIK32145.1 - 0.12 12.4 4.9 0.11 12.5 2.2 2.2 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion FAM184 PF15665.5 KIK32145.1 - 0.13 12.0 4.9 0.2 11.4 1.6 2.2 1 1 0 2 2 2 0 Family with sequence similarity 184, A and B IFT20 PF14931.6 KIK32145.1 - 0.16 12.2 1.6 2.6 8.2 0.0 2.4 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Laminin_II PF06009.12 KIK32145.1 - 0.16 12.0 5.9 0.81 9.7 0.3 2.3 1 1 1 2 2 2 0 Laminin Domain II Jnk-SapK_ap_N PF09744.9 KIK32145.1 - 0.17 12.1 2.3 0.44 10.8 2.3 1.7 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 APG17 PF04108.12 KIK32145.1 - 0.19 10.8 6.2 0.45 9.6 6.2 1.6 1 1 0 1 1 1 0 Autophagy protein Apg17 DivIC PF04977.15 KIK32145.1 - 0.23 11.2 3.4 11 5.8 1.2 2.4 2 0 0 2 2 2 0 Septum formation initiator ADIP PF11559.8 KIK32145.1 - 0.26 11.4 4.3 0.84 9.7 4.3 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4164 PF13747.6 KIK32145.1 - 0.26 11.6 6.2 2.6 8.4 5.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Syntaxin PF00804.25 KIK32145.1 - 0.28 10.8 3.0 1.5 8.5 2.2 2.1 1 1 1 2 2 2 0 Syntaxin Bacillus_HBL PF05791.11 KIK32145.1 - 0.35 10.7 7.9 0.68 9.7 3.9 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) LPP PF04728.13 KIK32145.1 - 0.98 9.9 7.7 3.8 8.0 1.7 3.4 1 1 2 3 3 2 0 Lipoprotein leucine-zipper ATG16 PF08614.11 KIK32145.1 - 3.9 7.7 9.0 0.86 9.8 5.1 1.9 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) WD40 PF00400.32 KIK32146.1 - 1.4e-23 82.7 18.6 6.1e-09 36.4 1.4 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32146.1 - 5.6e-17 61.8 1.7 0.018 15.3 0.0 6.5 1 1 6 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK32146.1 - 1.7e-06 27.8 0.1 34 4.5 0.0 6.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK32146.1 - 2.9e-05 23.2 0.0 0.077 11.9 0.0 3.2 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK32146.1 - 0.0041 16.5 0.8 0.27 10.5 0.1 3.2 2 2 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK32146.1 - 0.0043 15.8 5.0 0.14 10.7 0.1 2.8 3 1 0 3 3 3 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KIK32146.1 - 0.0044 17.5 3.0 0.41 11.2 1.5 4.0 4 1 0 4 4 4 1 PQQ-like domain WD40_like PF17005.5 KIK32146.1 - 0.19 11.0 0.0 6.9 5.9 0.0 2.7 2 1 0 2 2 2 0 WD40-like domain DUF659 PF04937.15 KIK32149.1 - 0.081 12.8 0.1 0.097 12.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Helo_like_N PF17111.5 KIK32149.1 - 0.089 12.1 0.1 0.094 12.1 0.1 1.0 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins AAA_16 PF13191.6 KIK32150.1 - 2.7e-06 27.9 0.2 1.2e-05 25.7 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KIK32150.1 - 9e-06 25.7 0.0 2.8e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 KIK32150.1 - 0.00058 19.8 0.0 0.0017 18.3 0.0 1.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 KIK32150.1 - 0.0039 17.1 0.0 0.29 11.0 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain Parvo_NS1 PF01057.17 KIK32150.1 - 0.008 15.3 0.0 0.018 14.1 0.0 1.6 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA PF00004.29 KIK32150.1 - 0.011 16.2 0.0 0.042 14.3 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_PrkA PF08298.11 KIK32150.1 - 0.024 13.5 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain RNA_helicase PF00910.22 KIK32150.1 - 0.045 14.2 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase PhoU PF01895.19 KIK32150.1 - 0.067 13.7 1.1 0.59 10.6 0.1 2.7 2 0 0 2 2 2 0 PhoU domain AAA_22 PF13401.6 KIK32150.1 - 0.074 13.3 0.0 0.34 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KIK32150.1 - 0.086 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 KIK32150.1 - 0.12 11.5 0.0 0.28 10.3 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain RhoGEF PF00621.20 KIK32150.1 - 1.2 9.4 4.4 1.5 9.0 1.7 2.6 3 1 0 3 3 3 0 RhoGEF domain Asp5 PF17000.5 KIK32151.1 - 0.078 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Accessory secretory protein Sec, Asp5 zf-RRN7 PF11781.8 KIK32154.1 - 0.079 12.7 4.7 2 8.2 0.7 2.6 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 GCIP PF13324.6 KIK32154.1 - 0.29 10.7 1.4 0.45 10.1 1.4 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting WD40 PF00400.32 KIK32155.1 - 5.6e-28 96.6 1.8 0.00032 21.4 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32155.1 - 3.6e-11 43.2 0.0 0.0021 18.3 0.0 4.5 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK32155.1 - 7.4e-06 25.2 0.0 0.00019 20.5 0.0 2.8 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK32155.1 - 4.9e-05 23.3 0.0 0.27 11.1 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A 2OG-FeII_Oxy_3 PF13640.6 KIK32157.1 - 9.4e-11 42.5 0.7 2.5e-10 41.1 0.7 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KIK32157.1 - 0.022 15.3 0.2 0.047 14.2 0.2 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Gemini_mov PF01708.16 KIK32159.1 - 1.4 8.7 3.0 4.7 7.1 0.0 2.3 1 1 1 2 2 2 0 Geminivirus putative movement protein ORC6 PF05460.13 KIK32159.1 - 2.8 7.1 12.8 3.3 6.9 12.8 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CDC45 PF02724.14 KIK32159.1 - 3.8 5.7 8.8 4.3 5.5 8.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF5546 PF17700.1 KIK32160.1 - 0.15 12.4 0.1 1.1 9.6 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5546) WD40 PF00400.32 KIK32161.1 - 1.4e-42 142.8 22.5 5.3e-09 36.6 4.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32161.1 - 1.9e-18 66.6 10.5 0.0002 21.6 0.2 6.1 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK32161.1 - 1.3e-06 28.0 0.0 6.2e-05 22.5 0.0 3.0 2 1 0 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 KIK32161.1 - 1.4e-06 27.5 0.1 0.34 9.8 0.0 4.3 1 1 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK32161.1 - 8.8e-06 24.6 13.1 0.31 9.6 0.3 4.8 3 1 1 5 5 5 4 Nucleoporin Nup120/160 PQQ PF01011.21 KIK32161.1 - 4.3e-05 23.2 0.1 2.3 8.3 0.0 4.5 4 0 0 4 4 4 2 PQQ enzyme repeat Cytochrom_D1 PF02239.16 KIK32161.1 - 0.00013 20.6 0.2 0.0034 16.0 0.2 2.8 2 1 1 3 3 3 1 Cytochrome D1 heme domain Nbas_N PF15492.6 KIK32161.1 - 0.0028 17.1 0.5 0.089 12.1 0.1 3.3 3 2 2 5 5 5 1 Neuroblastoma-amplified sequence, N terminal PQQ_3 PF13570.6 KIK32161.1 - 0.13 12.8 7.4 2.1 9.0 1.8 4.3 3 1 1 4 4 4 0 PQQ-like domain Frtz PF11768.8 KIK32161.1 - 0.19 10.0 0.0 3.8 5.7 0.0 2.6 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz GATA PF00320.27 KIK32163.1 - 2.1e-09 36.8 2.8 4.1e-09 35.9 2.8 1.4 1 0 0 1 1 1 1 GATA zinc finger TetR_C_15 PF17918.1 KIK32164.1 - 0.75 10.6 3.3 7.2 7.4 0.1 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Zn_clus PF00172.18 KIK32164.1 - 0.77 9.9 8.8 5.1 7.3 8.8 2.2 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NMD3 PF04981.13 KIK32165.1 - 2.4e-79 266.3 0.5 3.3e-79 265.8 0.5 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 KIK32165.1 - 0.0088 16.1 6.0 0.055 13.5 2.7 2.6 1 1 2 3 3 3 3 Double zinc ribbon NinF PF05810.12 KIK32165.1 - 0.034 14.0 1.1 0.15 12.0 0.5 2.3 3 0 0 3 3 3 0 NinF protein HEPN_Apea PF18739.1 KIK32165.1 - 0.16 12.5 0.1 0.3 11.5 0.1 1.5 1 0 0 1 1 1 0 Apea-like HEPN Rpr2 PF04032.16 KIK32165.1 - 0.19 12.0 3.4 14 6.1 0.1 3.1 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Vma12 PF11712.8 KIK32167.1 - 0.49 10.5 6.2 0.074 13.1 0.9 2.4 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase CHAT PF12770.7 KIK32168.1 - 2.7e-40 138.6 0.0 3.8e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 CHAT domain DUF3187 PF11383.8 KIK32169.1 - 0.014 14.7 0.0 0.015 14.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3187) DMSP_lyase PF16867.5 KIK32169.1 - 0.054 13.1 0.1 0.056 13.1 0.1 1.1 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase PIF1 PF05970.14 KIK32170.1 - 1.5e-23 83.6 0.0 1.5e-23 83.5 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIK32170.1 - 0.035 13.8 0.0 0.045 13.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 KIK32171.1 - 4.2e-19 69.0 0.0 4.5e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIK32171.1 - 4.5e-06 26.5 0.0 5e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK32171.1 - 8.9e-05 22.9 0.0 0.0001 22.7 0.0 1.0 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 KIK32171.1 - 0.00031 20.1 0.0 0.00035 19.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KIK32171.1 - 0.00047 20.2 0.0 0.00051 20.1 0.0 1.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 KIK32171.1 - 0.0034 17.2 0.0 0.0034 17.2 0.0 1.0 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KIK32171.1 - 0.0077 15.7 0.0 0.023 14.2 0.0 1.6 1 1 1 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.17 KIK32171.1 - 0.011 15.5 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.29 KIK32171.1 - 0.013 15.9 0.0 0.018 15.4 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KIK32171.1 - 0.026 13.8 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 KIK32171.1 - 0.03 14.7 0.0 0.032 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK32171.1 - 0.031 14.5 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2791 PF10923.8 KIK32171.1 - 0.041 12.7 0.0 0.042 12.7 0.0 1.0 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) MeaB PF03308.16 KIK32171.1 - 0.042 12.8 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TrwB_AAD_bind PF10412.9 KIK32171.1 - 0.068 12.1 0.0 0.074 11.9 0.0 1.0 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 KIK32171.1 - 0.075 13.4 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KIK32171.1 - 0.099 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.7 KIK32171.1 - 0.11 11.3 0.0 0.13 11.2 0.0 1.0 1 0 0 1 1 1 0 AAA-like domain AAA_3 PF07726.11 KIK32171.1 - 0.18 11.7 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIK32171.1 - 0.18 11.8 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 KIK32171.1 - 0.2 10.7 0.0 0.23 10.5 0.0 1.0 1 0 0 1 1 1 0 Type II/IV secretion system protein Plavaka PF18759.1 KIK32175.1 - 1.3e-86 290.8 7.2 8.9e-67 225.6 1.0 2.2 1 1 1 2 2 2 2 Plavaka transposase tRNA-synt_1f PF01921.18 KIK32175.1 - 0.042 12.8 0.0 2.7 6.8 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (K) TACI-CRD2 PF09305.10 KIK32175.1 - 0.08 13.0 0.2 19 5.4 0.0 2.5 2 0 0 2 2 2 0 TACI, cysteine-rich domain KN_motif PF12075.8 KIK32178.1 - 0.21 11.4 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 KN motif Tet_JBP PF12851.7 KIK32179.1 - 2.2e-05 24.0 0.0 2.7e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Pkinase_Tyr PF07714.17 KIK32180.1 - 1.1e-39 136.3 0.0 1.8e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK32180.1 - 1.6e-31 109.7 0.0 2.6e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIK32180.1 - 0.071 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KIK32180.1 - 0.11 12.5 0.1 0.66 9.8 0.1 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family Cytadhesin_P30 PF07271.11 KIK32180.1 - 0.11 12.1 1.4 0.21 11.1 1.1 1.5 2 0 0 2 2 2 0 Cytadhesin P30/P32 Dimer_Tnp_hAT PF05699.14 KIK32182.1 - 1.1e-14 53.9 1.4 1.6e-14 53.4 1.4 1.4 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region Ribosomal_L37ae PF01780.19 KIK32186.1 - 0.047 13.8 0.0 0.052 13.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal L37ae protein family Plavaka PF18759.1 KIK32188.1 - 3.4e-41 141.5 0.0 5.2e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase TP_methylase PF00590.20 KIK32189.1 - 2.7e-31 109.2 2.0 2.7e-31 109.2 2.0 1.9 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 KIK32189.1 - 9.2e-11 42.1 0.0 2.3e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KIK32189.1 - 1.2e-08 34.5 2.2 3.6e-07 29.7 0.8 2.3 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KIK32189.1 - 1.7e-07 30.6 0.0 3.7e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central DUF1380 PF07128.12 KIK32190.1 - 0.071 13.3 0.0 0.097 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1380) zf-CCHC_6 PF15288.6 KIK32191.1 - 0.0087 15.9 1.0 0.0087 15.9 1.0 2.4 2 0 0 2 2 2 1 Zinc knuckle PolC_DP2 PF03833.13 KIK32191.1 - 0.97 7.2 4.3 1.1 7.0 4.3 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 GPR15L PF15854.5 KIK32191.1 - 1.5 9.1 4.3 2.3 8.5 4.3 1.3 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 RecR PF02132.15 KIK32191.1 - 8.1 6.1 9.9 12 5.5 3.0 3.0 2 1 0 2 2 2 0 RecR protein Retrotran_gag_2 PF14223.6 KIK32194.1 - 2.1e-06 27.5 0.0 2.5e-06 27.2 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type WD40 PF00400.32 KIK32197.1 - 4.8e-10 39.9 0.0 0.0085 16.9 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32197.1 - 5.7e-05 23.3 0.0 0.038 14.3 0.0 2.9 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK32197.1 - 0.014 15.3 0.1 7.1 6.7 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK32197.1 - 0.015 14.3 0.1 0.18 10.7 0.0 2.0 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RVT_1 PF00078.27 KIK32199.1 - 0.062 12.8 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) ER-remodelling PF14755.6 KIK32203.1 - 0.66 10.3 7.4 4.3 7.6 0.0 2.9 2 1 1 3 3 3 0 Intracellular membrane remodeller DUF640 PF04852.12 KIK32205.1 - 0.07 13.3 0.8 0.087 13.0 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF640) Pkinase_Tyr PF07714.17 KIK32208.1 - 2.1e-21 76.4 0.0 2.7e-21 76.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK32208.1 - 8.2e-21 74.5 0.0 9.7e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain SBBP PF06739.11 KIK32208.1 - 0.018 15.0 0.2 0.038 14.0 0.2 1.6 1 0 0 1 1 1 0 Beta-propeller repeat Pkinase_Tyr PF07714.17 KIK32209.1 - 3.4e-16 59.3 0.0 3.8e-15 55.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK32209.1 - 2.8e-11 43.3 0.0 4.8e-11 42.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain AlgF PF11182.8 KIK32211.1 - 0.14 11.9 0.0 0.41 10.4 0.0 1.7 2 0 0 2 2 2 0 Alginate O-acetyl transferase AlgF Rop PF01815.16 KIK32211.1 - 0.18 11.7 1.5 0.33 10.8 0.5 1.8 2 0 0 2 2 2 0 Rop protein Plavaka PF18759.1 KIK32212.1 - 4.1e-129 430.5 0.1 5.5e-129 430.0 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase DARPP-32 PF05395.12 KIK32213.1 - 0.098 12.9 0.2 0.12 12.6 0.2 1.1 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Dimer_Tnp_hAT PF05699.14 KIK32216.1 - 1.2e-09 37.8 0.3 1.5e-09 37.5 0.3 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region 2OG-FeII_Oxy PF03171.20 KIK32217.1 - 4.2e-13 49.6 0.0 5.5e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-C2HC_2 PF13913.6 KIK32218.1 - 0.0041 17.0 1.1 0.011 15.7 1.1 1.8 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 KIK32218.1 - 0.031 14.7 0.6 0.1 13.1 0.6 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type Jiraiya PF15038.6 KIK32220.1 - 0.033 13.6 0.5 0.06 12.8 0.5 1.4 1 0 0 1 1 1 0 Jiraiya MWFE PF15879.5 KIK32220.1 - 0.033 14.3 0.3 3.5 7.8 0.0 2.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit DUF3169 PF11368.8 KIK32222.1 - 0.1 12.1 1.1 0.19 11.2 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Dimer_Tnp_hAT PF05699.14 KIK32223.1 - 1.2e-09 37.9 0.1 1.5e-09 37.5 0.1 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF5364 PF17322.2 KIK32224.1 - 0.059 13.7 3.3 0.079 13.3 3.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5364) WD40 PF00400.32 KIK32226.1 - 2e-27 94.8 6.3 1.2e-07 32.3 0.2 4.5 4 1 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32226.1 - 6.3e-11 42.4 0.6 0.0056 17.0 0.0 4.1 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK32226.1 - 0.00012 21.1 0.1 1.5 7.7 0.0 3.6 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK32226.1 - 0.00037 20.3 0.0 2.9 7.9 0.0 4.2 4 1 0 4 4 4 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK32226.1 - 0.0025 16.5 0.2 0.0076 14.9 0.1 1.7 1 1 1 2 2 2 1 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KIK32226.1 - 0.038 12.9 0.0 1.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Glyco_trans_2_3 PF13632.6 KIK32228.1 - 2.2e-35 122.4 0.1 2.8e-35 122.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KIK32228.1 - 0.0019 18.1 0.2 0.0056 16.6 0.2 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIK32228.1 - 0.096 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Dimer_Tnp_hAT PF05699.14 KIK32229.1 - 1.4e-11 44.1 0.1 2.1e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF35_N PF12172.8 KIK32230.1 - 4.5 7.2 7.9 6.9 6.7 0.5 2.5 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) RVP_2 PF08284.11 KIK32231.1 - 5e-07 29.6 0.0 5.4e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KIK32231.1 - 3.4e-06 27.5 0.0 4.4e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIK32231.1 - 3.2e-05 24.5 0.0 3.8e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 Aspartyl protease DUF3463 PF11946.8 KIK32234.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) WLM PF08325.10 KIK32235.1 - 9e-38 130.3 0.9 1.8e-37 129.3 0.3 1.7 1 1 0 1 1 1 1 WLM domain ubiquitin PF00240.23 KIK32235.1 - 0.0021 17.7 0.0 0.042 13.6 0.0 3.0 3 1 0 3 3 3 1 Ubiquitin family SprT-like PF10263.9 KIK32235.1 - 0.032 14.1 0.2 0.074 12.9 0.2 1.7 1 1 0 1 1 1 0 SprT-like family Ubiquitin_2 PF14560.6 KIK32235.1 - 0.046 14.2 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain RPAP1_C PF08620.10 KIK32235.1 - 0.095 12.8 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 RPAP1-like, C-terminal Plavaka PF18759.1 KIK32237.1 - 5.1e-34 118.0 0.0 1e-33 117.0 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase WD40 PF00400.32 KIK32240.1 - 1 10.3 3.4 0.51 11.3 0.9 1.8 2 0 0 2 2 2 0 WD domain, G-beta repeat HTH_IclR PF09339.10 KIK32243.1 - 0.0008 19.2 0.3 0.031 14.1 0.0 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_23 PF13384.6 KIK32243.1 - 0.0012 18.6 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_8 PF02954.19 KIK32243.1 - 0.0043 16.8 0.1 0.019 14.8 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family HTH_11 PF08279.12 KIK32243.1 - 0.0052 16.7 0.0 0.0088 16.0 0.0 1.3 1 0 0 1 1 1 1 HTH domain HTH_3 PF01381.22 KIK32243.1 - 0.019 15.0 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix HTH_17 PF12728.7 KIK32243.1 - 0.02 15.1 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_30 PF13556.6 KIK32243.1 - 0.033 14.0 0.1 0.077 12.8 0.1 1.7 1 1 0 1 1 1 0 PucR C-terminal helix-turn-helix domain MerR PF00376.23 KIK32243.1 - 0.037 13.8 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 MerR family regulatory protein MerR_1 PF13411.6 KIK32243.1 - 0.037 14.1 0.0 0.059 13.5 0.0 1.3 1 0 0 1 1 1 0 MerR HTH family regulatory protein HTH_10 PF04967.12 KIK32243.1 - 0.056 13.2 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 HTH DNA binding domain HTH_29 PF13551.6 KIK32243.1 - 0.063 13.3 0.0 2.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix HTH_26 PF13443.6 KIK32243.1 - 0.071 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_DeoR PF08220.12 KIK32243.1 - 0.1 12.4 0.2 0.16 11.7 0.2 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 KIK32243.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Tc3 transposase HTH_28 PF13518.6 KIK32243.1 - 0.2 11.8 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain BTB PF00651.31 KIK32244.1 - 4.3e-06 26.9 0.1 5.4e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 BTB/POZ domain GCR1_C PF12550.8 KIK32246.1 - 5.6e-11 42.6 0.1 9.2e-11 41.9 0.1 1.3 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Peptidase_S9_N PF02897.15 KIK32247.1 - 0.18 10.6 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Synapsin_N PF10581.9 KIK32248.1 - 0.059 13.3 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Synapsin N-terminal YjeJ PF15922.5 KIK32249.1 - 0.17 11.1 0.0 0.2 10.8 0.0 1.0 1 0 0 1 1 1 0 YjeJ-like RRN3 PF05327.11 KIK32252.1 - 0.037 12.6 3.0 0.036 12.6 3.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Peptidase_M41 PF01434.18 KIK32252.1 - 0.073 12.9 0.5 4.4 7.1 0.0 2.1 1 1 1 2 2 2 0 Peptidase family M41 F-box PF00646.33 KIK32253.1 - 0.075 12.9 0.1 0.23 11.4 0.1 1.8 1 1 0 1 1 1 0 F-box domain zf-RVT PF13966.6 KIK32255.1 - 0.005 17.5 2.7 0.0058 17.3 1.5 1.7 1 1 1 2 2 2 1 zinc-binding in reverse transcriptase Thioredoxin_5 PF13743.6 KIK32255.1 - 0.038 13.7 0.0 0.039 13.6 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Plavaka PF18759.1 KIK32256.1 - 4.9e-19 68.7 0.1 7.8e-19 68.1 0.1 1.3 1 0 0 1 1 1 1 Plavaka transposase DUF3638 PF12340.8 KIK32258.1 - 7.3e-92 306.8 0.3 1.1e-91 306.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KIK32258.1 - 1.2e-16 59.7 1.8 1.3e-16 59.6 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3645) Dimer_Tnp_hAT PF05699.14 KIK32259.1 - 5.3e-17 61.4 0.1 1.8e-16 59.7 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KIK32259.1 - 0.00051 20.4 0.1 0.0011 19.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) MMR_HSR1 PF01926.23 KIK32260.1 - 9.2e-14 51.5 0.1 1.1e-13 51.3 0.1 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK32260.1 - 1.3e-11 44.2 0.2 1.5e-11 44.1 0.2 1.1 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KIK32260.1 - 9.3e-07 28.9 0.1 3.6e-06 27.0 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KIK32260.1 - 3.7e-06 27.1 1.0 0.00033 20.7 0.6 2.1 1 1 1 2 2 2 1 Dynamin family Ras PF00071.22 KIK32260.1 - 1.4e-05 24.8 1.0 5e-05 23.0 0.9 1.8 1 1 0 1 1 1 1 Ras family RNA_helicase PF00910.22 KIK32260.1 - 3.3e-05 24.2 0.0 6.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Septin PF00735.18 KIK32260.1 - 0.00013 21.3 0.1 0.00019 20.8 0.1 1.1 1 0 0 1 1 1 1 Septin FtsK_SpoIIIE PF01580.18 KIK32260.1 - 0.00072 19.0 0.0 0.0016 17.9 0.0 1.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.6 KIK32260.1 - 0.00088 19.6 0.2 0.0016 18.7 0.2 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KIK32260.1 - 0.001 19.6 0.3 0.0018 18.8 0.3 1.4 1 1 0 1 1 1 1 ABC transporter Roc PF08477.13 KIK32260.1 - 0.0028 17.9 0.4 0.0049 17.1 0.2 1.5 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KIK32260.1 - 0.005 17.2 0.0 0.0081 16.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.17 KIK32260.1 - 0.0077 16.3 0.0 0.0099 16.0 0.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_29 PF13555.6 KIK32260.1 - 0.013 15.2 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.10 KIK32260.1 - 0.019 14.4 0.2 0.026 14.0 0.2 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KIK32260.1 - 0.023 14.1 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_23 PF13476.6 KIK32260.1 - 0.028 14.9 1.3 0.041 14.4 0.9 1.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK32260.1 - 0.033 13.7 0.1 0.05 13.1 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 KIK32260.1 - 0.039 14.3 0.0 0.042 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIK32260.1 - 0.047 13.6 0.1 0.1 12.5 0.1 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea FeoB_N PF02421.18 KIK32260.1 - 0.051 13.1 0.1 0.054 13.0 0.1 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B T2SSE PF00437.20 KIK32260.1 - 0.076 12.1 0.1 0.095 11.7 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KIK32260.1 - 0.097 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.13 KIK32260.1 - 0.1 11.8 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KIK32260.1 - 0.11 12.2 0.1 0.22 11.3 0.1 1.3 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 KIK32260.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase SMC_N PF02463.19 KIK32260.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain IIGP PF05049.13 KIK32260.1 - 0.16 11.0 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Guanylate_kin PF00625.21 KIK32260.1 - 0.16 11.6 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Guanylate kinase AAA_18 PF13238.6 KIK32260.1 - 0.18 12.3 0.0 0.24 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KIK32260.1 - 0.2 11.4 0.0 0.25 11.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 KIK32260.1 - 0.21 10.2 0.1 0.26 9.9 0.1 1.1 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 KIK32261.1 - 1.5e-20 73.7 0.0 2e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK32261.1 - 4.2e-18 65.6 0.0 4.8e-18 65.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK32261.1 - 0.0047 16.9 0.0 0.0073 16.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK32261.1 - 0.15 11.6 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 KIK32261.1 - 0.16 11.0 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 RecR PF02132.15 KIK32262.1 - 0.072 12.7 0.8 0.17 11.5 0.8 1.6 1 0 0 1 1 1 0 RecR protein WD40 PF00400.32 KIK32263.1 - 2.1e-31 107.5 18.5 1.4e-08 35.2 0.1 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32263.1 - 4.6e-13 49.3 0.7 0.012 15.9 0.0 4.7 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK32263.1 - 0.0002 20.4 0.7 4.3 6.2 0.0 4.2 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK32263.1 - 0.00081 18.2 1.7 0.0049 15.6 0.3 2.6 1 1 1 3 3 3 1 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK32263.1 - 0.0026 17.2 0.3 0.38 10.0 0.0 3.0 2 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Holin_9 PF16936.5 KIK32264.1 - 0.078 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative holin Birna_VP2 PF01766.17 KIK32264.1 - 0.13 11.3 0.0 0.15 11.1 0.0 1.0 1 0 0 1 1 1 0 Birnavirus VP2 protein Pkinase_fungal PF17667.1 KIK32265.1 - 8.6e-15 54.4 0.0 1e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Lpp-LpqN PF10738.9 KIK32266.1 - 0.051 13.0 0.1 0.084 12.3 0.1 1.4 1 1 0 1 1 1 0 Probable lipoprotein LpqN CDRT4 PF15213.6 KIK32266.1 - 0.059 14.0 0.2 0.1 13.2 0.2 1.3 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein MU117 PF15474.6 KIK32266.1 - 0.11 13.3 1.3 0.18 12.6 0.2 1.9 2 1 0 2 2 2 0 Meiotically up-regulated gene family MULE PF10551.9 KIK32267.1 - 0.00074 19.9 0.3 0.0062 16.9 0.2 2.2 2 0 0 2 2 2 1 MULE transposase domain Dynein_AAA_lid PF17852.1 KIK32268.1 - 0.1 12.7 0.1 0.42 10.7 0.0 1.9 2 1 0 2 2 2 0 Dynein heavy chain AAA lid domain SAD_SRA PF02182.17 KIK32271.1 - 2e-45 154.3 0.0 2.5e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 SAD/SRA domain PAP2_3 PF14378.6 KIK32273.1 - 0.033 13.9 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 PAP2 superfamily WD40 PF00400.32 KIK32275.1 - 9e-19 67.5 0.3 4.9e-09 36.7 0.1 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32275.1 - 0.00054 20.2 0.0 0.027 14.8 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK32275.1 - 0.0029 16.4 0.3 0.0062 15.2 0.1 1.5 1 1 1 2 2 2 1 Nucleoporin Nup120/160 PD40 PF07676.12 KIK32275.1 - 0.022 14.7 0.1 1.3 9.1 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat HMG_box_2 PF09011.10 KIK32277.1 - 0.0094 16.5 0.0 0.01 16.4 0.0 1.1 1 0 0 1 1 1 1 HMG-box domain Plavaka PF18759.1 KIK32278.1 - 1.9e-36 125.9 0.0 9.8e-36 123.6 0.0 1.8 1 1 0 1 1 1 1 Plavaka transposase WD40 PF00400.32 KIK32279.1 - 4.6e-144 464.0 43.2 7.4e-11 42.4 0.2 14.8 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32279.1 - 7.8e-52 173.5 0.0 0.0079 16.5 0.0 14.2 1 1 11 14 14 14 13 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK32279.1 - 1.3e-35 122.9 10.5 0.0053 15.7 0.0 14.0 9 2 5 14 14 14 11 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK32279.1 - 1.8e-13 50.0 36.7 0.89 9.6 0.0 13.6 15 0 0 15 15 15 7 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK32279.1 - 6.4e-13 48.7 0.0 0.12 11.7 0.0 8.5 8 1 0 9 9 9 2 WD40-like domain Nup160 PF11715.8 KIK32279.1 - 2.5e-11 42.9 3.8 6.6 5.2 0.0 10.1 6 2 6 12 12 12 1 Nucleoporin Nup120/160 Peptidase_S9_N PF02897.15 KIK32279.1 - 4.3e-08 32.4 0.0 0.9 8.3 0.0 6.4 3 2 2 7 7 7 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Frtz PF11768.8 KIK32279.1 - 1.6e-06 26.8 0.0 1.9 6.7 0.0 7.0 3 2 6 10 10 10 2 WD repeat-containing and planar cell polarity effector protein Fritz CHAP PF05257.16 KIK32279.1 - 2.8e-05 24.6 7.5 21 5.8 0.2 8.2 7 2 3 10 10 10 0 CHAP domain Nbas_N PF15492.6 KIK32279.1 - 4.1e-05 23.1 15.6 4.7 6.5 0.0 9.9 9 3 3 13 13 13 1 Neuroblastoma-amplified sequence, N terminal PQQ PF01011.21 KIK32279.1 - 4.7e-05 23.1 0.8 6 7.0 0.0 6.5 7 0 0 7 7 7 1 PQQ enzyme repeat PQQ_2 PF13360.6 KIK32279.1 - 0.00064 19.4 4.5 0.00064 19.4 4.5 4.9 1 1 2 3 3 3 1 PQQ-like domain Cuticle_4 PF15955.5 KIK32279.1 - 0.016 15.9 0.6 1.4e+02 3.3 0.0 5.8 8 0 0 8 8 6 0 Cuticle protein DPPIV_N PF00930.21 KIK32279.1 - 0.21 10.3 0.9 1.4e+02 1.0 0.0 5.0 6 1 1 7 7 7 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40 PF00400.32 KIK32280.1 - 1.2e-42 143.1 28.6 5.7e-08 33.3 0.3 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32280.1 - 1.1e-16 60.9 7.1 0.0013 18.9 0.0 6.3 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KIK32280.1 - 1.2e-06 28.1 0.3 0.0017 17.8 0.0 4.4 2 1 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 KIK32280.1 - 7.4e-06 25.2 0.0 0.68 8.8 0.0 5.1 2 1 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK32280.1 - 3.4e-05 22.7 4.7 3 6.4 0.1 4.5 3 2 2 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK32280.1 - 0.028 13.8 0.0 2.7 7.2 0.0 3.3 3 1 1 4 4 4 0 WD40-like domain Cytochrom_D1 PF02239.16 KIK32280.1 - 0.043 12.3 0.1 0.57 8.7 0.0 2.4 2 1 0 2 2 2 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 KIK32280.1 - 0.077 11.7 0.0 12 4.5 0.0 3.1 2 1 1 3 3 3 0 Nup133 N terminal like PD40 PF07676.12 KIK32280.1 - 0.095 12.7 0.4 14 5.7 0.1 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK32280.1 - 0.15 10.3 0.0 1.6 7.0 0.0 2.2 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz YrhC PF14143.6 KIK32281.1 - 0.055 13.6 0.9 0.1 12.7 0.9 1.4 1 0 0 1 1 1 0 YrhC-like protein Peptidase_M17 PF00883.21 KIK32284.1 - 1.4e-54 185.5 0.0 1.8e-54 185.1 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 KIK32284.1 - 1.6e-06 28.0 0.0 3.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Plavaka PF18759.1 KIK32293.1 - 5.7e-39 134.2 0.0 7.2e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase YqzE PF14038.6 KIK32295.1 - 0.65 10.0 2.3 2.1 8.4 0.0 2.3 2 0 0 2 2 2 0 YqzE-like protein FXMRP1_C_core PF12235.8 KIK32296.1 - 0.61 10.7 0.1 0.61 10.7 0.1 2.6 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Hemopexin PF00045.19 KIK32300.1 - 0.05 13.5 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Hemopexin DEAD PF00270.29 KIK32303.1 - 3.6e-14 52.9 0.0 5.7e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK32303.1 - 6.2e-08 33.0 0.0 1.3e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_14 PF13173.6 KIK32303.1 - 0.033 14.2 0.0 4.6 7.3 0.0 2.4 1 1 1 2 2 2 0 AAA domain Asp_protease PF09668.10 KIK32306.1 - 0.00094 19.0 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 KIK32306.1 - 0.00099 19.7 0.0 0.0029 18.2 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK32306.1 - 0.0026 18.3 0.0 0.004 17.7 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 KIK32306.1 - 0.03 14.6 0.0 0.049 13.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Peptidase_A2E PF12382.8 KIK32306.1 - 0.16 12.0 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Retrotransposon peptidase CENP-H PF05837.12 KIK32308.1 - 0.0011 19.3 4.3 0.0014 19.0 4.3 1.1 1 0 0 1 1 1 1 Centromere protein H (CENP-H) DHR10 PF18595.1 KIK32308.1 - 0.0044 17.1 7.1 0.023 14.7 7.1 1.8 1 1 0 1 1 1 1 Designed helical repeat protein 10 domain GIT_CC PF16559.5 KIK32308.1 - 0.019 14.8 0.8 0.037 13.9 0.8 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor FAM184 PF15665.5 KIK32308.1 - 0.052 13.3 5.2 0.065 13.0 5.2 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Sec8_exocyst PF04048.14 KIK32308.1 - 0.062 13.2 2.3 3.8 7.4 0.0 2.1 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Atg14 PF10186.9 KIK32308.1 - 0.083 12.0 2.7 0.094 11.8 2.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KIK32308.1 - 0.14 11.0 6.1 1 8.1 2.4 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 KIK32308.1 - 0.77 10.3 8.1 0.51 10.9 6.1 1.6 1 1 1 2 2 2 0 Apg6 coiled-coil region DivIC PF04977.15 KIK32308.1 - 4 7.3 8.6 0.57 10.0 1.3 2.4 1 1 1 2 2 2 0 Septum formation initiator Glycos_transf_1 PF00534.20 KIK32309.1 - 0.023 14.2 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KIK32309.1 - 0.028 14.1 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Starch synthase catalytic domain DUF4585 PF15232.6 KIK32310.1 - 0.019 15.0 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) TPR_12 PF13424.6 KIK32312.1 - 0.019 15.2 1.8 9.9 6.5 0.0 3.2 2 2 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK32312.1 - 0.037 14.1 0.2 7.1 6.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK32312.1 - 0.15 11.9 3.7 3.8 7.5 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK32312.1 - 0.25 11.5 1.4 1.7 8.9 0.1 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIK32312.1 - 0.45 10.5 9.2 17 5.5 0.8 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat Astacin PF01400.24 KIK32316.1 - 0.047 13.3 0.1 0.079 12.6 0.1 1.3 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Myosin_N PF02736.19 KIK32317.1 - 0.039 13.8 0.2 0.052 13.4 0.2 1.2 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Helicase_C PF00271.31 KIK32321.1 - 7.9e-15 55.2 0.0 1.4e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KIK32321.1 - 0.00015 21.1 0.0 0.00023 20.5 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SNF2_N PF00176.23 KIK32321.1 - 0.00089 18.1 0.1 0.0013 17.5 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KIK32321.1 - 0.038 14.0 0.0 0.23 11.5 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SNF5 PF04855.12 KIK32322.1 - 6.9e-09 35.8 0.0 1.7e-06 28.0 0.1 2.2 2 0 0 2 2 2 2 SNF5 / SMARCB1 / INI1 CDC27 PF09507.10 KIK32324.1 - 0.071 12.5 4.6 0.091 12.1 4.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PBP1_TM PF14812.6 KIK32324.1 - 0.29 11.5 6.4 0.7 10.3 6.4 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AC_N PF16214.5 KIK32324.1 - 6.3 5.8 9.0 1.5 7.8 0.2 2.1 1 1 0 2 2 2 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF4413 PF14372.6 KIK32326.1 - 0.064 13.6 0.1 0.15 12.4 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4413) HpaB_N PF11794.8 KIK32326.1 - 0.094 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Dimer_Tnp_hAT PF05699.14 KIK32327.1 - 5.3e-12 45.4 0.0 5.5e-12 45.3 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region FHA PF00498.26 KIK32328.1 - 7.3e-17 61.5 0.1 8.8e-17 61.2 0.1 1.1 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIK32328.1 - 0.00016 21.9 0.0 0.00021 21.6 0.0 1.2 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Mating_C PF12737.7 KIK32329.1 - 0.15 11.3 0.6 0.23 10.7 0.6 1.3 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 TPR_10 PF13374.6 KIK32330.1 - 3.3e-07 30.0 8.4 0.007 16.2 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK32330.1 - 2.8e-06 27.5 15.6 1 9.7 0.0 7.7 4 2 4 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK32330.1 - 0.19 11.9 5.0 63 4.1 0.2 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KIK32330.1 - 0.28 10.7 1.2 7.7 6.1 0.1 3.1 2 0 0 2 2 2 0 SHNi-TPR Vta1_C PF18097.1 KIK32330.1 - 1.4 8.6 4.5 2 8.2 0.1 3.5 4 0 0 4 4 4 0 Vta1 C-terminal domain TPR_14 PF13428.6 KIK32330.1 - 2.9 8.9 14.1 11 7.2 0.1 6.2 6 1 1 7 7 7 0 Tetratricopeptide repeat DUF188 PF02639.14 KIK32331.1 - 0.2 11.3 0.3 0.39 10.4 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 DUF1838 PF08894.11 KIK32332.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1838) CxC6 PF18721.1 KIK32333.1 - 2e-15 56.8 13.3 4e-15 55.8 13.3 1.6 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases Amidohydro_1 PF01979.20 KIK32334.1 - 0.00011 21.6 0.0 0.0016 17.9 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIK32334.1 - 0.002 17.7 0.5 0.17 11.3 0.0 3.1 3 0 0 3 3 3 1 Amidohydrolase family Amidase PF01425.21 KIK32336.1 - 1.1e-77 261.9 0.0 4.6e-76 256.6 0.0 2.0 1 1 0 1 1 1 1 Amidase DUF4406 PF14359.6 KIK32336.1 - 0.03 14.8 0.0 0.072 13.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4406) p450 PF00067.22 KIK32337.1 - 7.2e-09 34.9 0.0 7.6e-09 34.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-CCHC PF00098.23 KIK32340.1 - 8.7e-05 22.4 2.3 0.00015 21.7 2.3 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 KIK32340.1 - 0.1 12.2 0.2 0.13 11.9 0.2 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Retrotran_gag_2 PF14223.6 KIK32341.1 - 3e-05 23.7 0.4 4.1e-05 23.3 0.4 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KIK32341.1 - 0.046 13.5 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RVT_thumb PF06817.14 KIK32343.1 - 0.03 14.2 0.2 0.13 12.1 0.0 1.9 1 1 1 2 2 2 0 Reverse transcriptase thumb domain Retrotran_gag_2 PF14223.6 KIK32345.1 - 0.00042 20.0 0.1 0.00059 19.5 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type YtxC PF08812.11 KIK32345.1 - 0.043 13.4 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 YtxC-like family Retrotran_gag_3 PF14244.6 KIK32345.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type rve PF00665.26 KIK32347.1 - 0.009 16.2 0.1 0.039 14.1 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Mob_synth_C PF06463.13 KIK32347.1 - 0.041 13.8 0.1 0.069 13.1 0.1 1.3 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C gag_pre-integrs PF13976.6 KIK32347.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 GAG-pre-integrase domain Peptidase_C39 PF03412.15 KIK32353.1 - 0.045 13.5 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase C39 family AHJR-like PF18743.1 KIK32354.1 - 0.02 14.5 0.4 0.067 12.8 0.4 1.9 1 1 0 1 1 1 0 REase_AHJR-like Sigma70_r4_2 PF08281.12 KIK32354.1 - 0.11 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 Pkinase_fungal PF17667.1 KIK32356.1 - 3.4e-69 233.6 0.0 1.9e-37 129.1 0.0 2.0 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIK32356.1 - 2e-07 30.6 0.0 2.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIK32356.1 - 0.0001 22.0 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIK32356.1 - 0.0012 18.9 0.1 0.0022 17.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIK32363.1 - 9.1e-07 28.5 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK32363.1 - 0.011 15.0 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Mito_fiss_reg PF05308.11 KIK32364.1 - 0.48 10.5 3.4 0.5 10.4 3.4 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Herpes_capsid PF06112.11 KIK32364.1 - 1.1 9.3 11.4 1.7 8.7 11.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Med3 PF11593.8 KIK32364.1 - 2.1 7.5 4.4 2.6 7.1 4.4 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ADH_N PF08240.12 KIK32365.1 - 1e-10 41.4 0.0 2.4e-10 40.2 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK32365.1 - 2.5e-08 34.0 0.0 4.4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK32365.1 - 0.028 15.5 0.0 0.048 14.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Zn_clus PF00172.18 KIK32367.1 - 0.29 11.3 21.6 0.27 11.4 5.0 3.2 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Med30 PF11315.8 KIK32368.1 - 0.073 13.3 0.2 0.17 12.1 0.2 1.6 1 0 0 1 1 1 0 Mediator complex subunit 30 WD40 PF00400.32 KIK32370.1 - 1.3e-28 98.6 3.8 7.4e-09 36.1 0.3 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32370.1 - 1.7e-09 37.8 0.4 0.063 13.6 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK32370.1 - 7.1e-05 21.6 0.8 0.0029 16.3 0.0 2.5 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK32370.1 - 0.00041 19.4 0.1 1.1 8.1 0.0 2.8 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KIK32370.1 - 0.027 13.0 0.0 0.042 12.4 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain HdeA PF06411.11 KIK32371.1 - 0.2 11.8 0.0 0.28 11.4 0.0 1.2 1 0 0 1 1 1 0 HdeA/HdeB family Reg_prop PF07494.11 KIK32372.1 - 0.021 15.0 1.0 0.61 10.5 0.1 2.9 2 0 0 2 2 2 0 Two component regulator propeller KfrA_N PF11740.8 KIK32373.1 - 0.0047 17.6 1.5 0.0076 16.9 1.4 1.5 1 1 0 1 1 1 1 Plasmid replication region DNA-binding N-term RNA_pol_Rpb2_3 PF04565.16 KIK32374.1 - 1.5e-07 31.5 0.1 2.6e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 DUF1737 PF08410.10 KIK32374.1 - 0.018 14.9 0.0 1.6 8.6 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1737) tRNA-synt_2d PF01409.20 KIK32374.1 - 0.033 13.7 0.1 2.6 7.4 0.1 3.1 1 1 0 1 1 1 0 tRNA synthetases class II core domain (F) DEAD PF00270.29 KIK32376.1 - 6e-33 114.1 0.1 7.2e-33 113.8 0.1 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase CxC2 PF18803.1 KIK32377.1 - 2.2e-44 150.0 1.2 2.2e-44 150.0 1.2 1.9 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK32377.1 - 3.9e-08 33.4 0.4 6.5e-08 32.7 0.4 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK32377.1 - 0.00055 19.8 0.2 0.00055 19.8 0.2 2.1 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 KIK32377.1 - 0.0021 18.2 7.7 0.0021 18.2 7.7 2.7 2 0 0 2 2 2 1 B-box zinc finger KDZ PF18758.1 KIK32378.1 - 5e-07 29.5 0.0 5.8e-07 29.3 0.0 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase EF-hand_like PF09279.11 KIK32379.1 - 0.081 13.4 0.8 0.15 12.6 0.4 1.6 1 1 1 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like RVT_1 PF00078.27 KIK32382.1 - 1.6e-05 24.5 0.0 1.6e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KIK32383.1 - 9.8e-06 25.5 0.0 1.1e-05 25.3 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KIK32384.1 - 0.0067 16.6 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DnaB_2 PF07261.11 KIK32385.1 - 0.18 11.6 0.0 12 5.8 0.0 2.1 2 0 0 2 2 2 0 Replication initiation and membrane attachment RT_RNaseH_2 PF17919.1 KIK32386.1 - 1.1e-08 35.0 0.0 3.5e-08 33.4 0.0 1.7 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KIK32386.1 - 0.001 19.3 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KIK32387.1 - 0.009 16.1 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain FadR_C PF07840.12 KIK32388.1 - 0.021 14.7 0.1 0.036 14.0 0.1 1.3 1 0 0 1 1 1 0 FadR C-terminal domain DEAD PF00270.29 KIK32389.1 - 1.7e-12 47.5 0.0 5.2e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK32389.1 - 9.5e-08 32.4 0.0 2.9e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_14 PF13173.6 KIK32389.1 - 0.19 11.8 0.0 16 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain DDE_Tnp_4 PF13359.6 KIK32391.1 - 3.3e-12 46.4 0.0 6.9e-09 35.6 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease Hyr1 PF15789.5 KIK32391.1 - 0.024 14.2 0.3 0.063 12.8 0.3 1.7 1 0 0 1 1 1 0 Hyphally regulated cell wall GPI-anchored protein 1 FUSC PF04632.12 KIK32392.1 - 0.91 8.0 7.5 1.2 7.6 7.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CR6_interact PF10147.9 KIK32393.1 - 0.015 15.0 6.4 0.019 14.7 6.4 1.1 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF745 PF05335.13 KIK32393.1 - 0.53 10.0 8.1 0.88 9.3 8.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Atg14 PF10186.9 KIK32393.1 - 0.92 8.5 10.0 1.2 8.1 10.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5423 PF17461.2 KIK32393.1 - 1.3 7.8 3.8 0.18 10.6 0.1 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5423) Plavaka PF18759.1 KIK32394.1 - 0.00089 18.6 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase DUF1851 PF08906.11 KIK32394.1 - 0.043 13.8 0.0 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1851) Plavaka PF18759.1 KIK32395.1 - 4.3e-15 55.8 0.1 7.4e-15 55.0 0.1 1.3 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK32400.1 - 1.5e-88 297.2 1.8 1.6e-56 191.9 0.2 2.1 1 1 1 2 2 2 2 Plavaka transposase Plavaka PF18759.1 KIK32401.1 - 0.00051 19.4 0.0 0.00074 18.8 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2_4 PF13894.6 KIK32401.1 - 0.11 13.4 0.2 0.11 13.4 0.2 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK32401.1 - 0.15 12.6 0.1 0.15 12.6 0.1 2.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type WD40 PF00400.32 KIK32402.1 - 8.7e-40 134.0 26.8 1.9e-06 28.5 0.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32402.1 - 7.7e-12 45.4 1.5 0.017 15.4 0.1 5.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WW PF00397.26 KIK32402.1 - 1.3e-06 28.3 0.6 1.3e-06 28.3 0.6 3.5 4 0 0 4 4 4 1 WW domain Nup160 PF11715.8 KIK32402.1 - 5.1e-06 25.4 0.2 0.13 10.9 0.2 3.4 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK32402.1 - 0.013 14.5 0.2 9.8 5.0 0.0 3.8 2 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Neisseria_TspB PF05616.13 KIK32402.1 - 0.19 10.1 0.0 0.37 9.2 0.0 1.4 2 0 0 2 2 2 0 Neisseria meningitidis TspB protein RVT_1 PF00078.27 KIK32407.1 - 2.4e-07 30.5 0.3 4.8e-07 29.5 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KIK32408.1 - 0.0072 15.9 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NACHT PF05729.12 KIK32409.1 - 9.7e-06 25.6 0.0 4e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK32409.1 - 5.6e-05 23.6 0.0 0.00028 21.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Parvo_NS1 PF01057.17 KIK32409.1 - 0.0031 16.6 0.0 0.0065 15.6 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 KIK32409.1 - 0.0052 16.0 0.0 0.011 14.9 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 KIK32409.1 - 0.021 15.2 0.1 0.082 13.3 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK32409.1 - 0.032 14.5 0.0 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIK32409.1 - 0.087 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK32409.1 - 0.088 13.2 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.20 KIK32409.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase UBN_AB PF14075.6 KIK32410.1 - 2.6e-24 86.1 0.1 1.5e-23 83.7 0.1 1.9 1 1 0 1 1 1 1 Ubinuclein conserved middle domain gag_pre-integrs PF13976.6 KIK32411.1 - 9.2e-09 35.0 0.1 1.5e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain KRAB PF01352.27 KIK32412.1 - 0.024 14.3 0.2 0.055 13.1 0.2 1.6 1 0 0 1 1 1 0 KRAB box CytB6-F_Fe-S PF08802.10 KIK32413.1 - 0.068 13.2 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit WD40 PF00400.32 KIK32416.1 - 5.9e-42 140.9 25.8 5.7e-07 30.1 0.4 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32416.1 - 2.3e-12 47.0 0.8 0.0093 16.3 0.0 5.1 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK32416.1 - 0.00014 20.7 0.0 0.18 10.4 0.2 3.6 3 1 1 4 4 4 1 Nucleoporin Nup120/160 WW PF00397.26 KIK32416.1 - 0.00051 20.1 0.4 0.00051 20.1 0.4 3.6 5 0 0 5 5 5 1 WW domain DUF3558 PF12079.8 KIK32416.1 - 0.025 14.6 0.5 2.6 8.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3558) Ge1_WD40 PF16529.5 KIK32416.1 - 0.036 13.0 0.1 14 4.6 0.0 3.8 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KIK32416.1 - 0.037 12.8 0.1 6.1 5.5 0.1 3.4 3 1 0 3 3 3 0 Nup133 N terminal like Cytochrom_D1 PF02239.16 KIK32416.1 - 0.056 12.0 0.1 0.1 11.1 0.1 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain WD40_like PF17005.5 KIK32416.1 - 0.25 10.6 0.0 7.3 5.8 0.0 2.3 1 1 1 2 2 2 0 WD40-like domain WD40 PF00400.32 KIK32422.1 - 1.9e-22 79.1 15.5 4.8e-09 36.7 1.3 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32422.1 - 2.9e-15 56.3 0.2 0.0014 18.8 0.0 5.9 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK32422.1 - 2.5e-08 34.0 0.1 0.00013 21.9 0.1 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK32422.1 - 3e-05 23.8 0.5 11 6.1 0.0 5.1 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK32422.1 - 0.00089 18.7 0.5 2.3 7.5 0.0 3.8 2 2 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK32422.1 - 0.08 11.6 2.8 12 4.4 0.3 3.2 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KIK32422.1 - 0.089 13.3 0.7 11 6.6 0.8 3.7 4 0 0 4 4 4 0 PQQ-like domain WD40_like PF17005.5 KIK32422.1 - 0.1 11.9 0.0 0.28 10.5 0.0 1.6 1 1 0 1 1 1 0 WD40-like domain Ge1_WD40 PF16529.5 KIK32422.1 - 0.11 11.5 0.0 0.58 9.1 0.0 2.1 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein F-box-like PF12937.7 KIK32423.1 - 0.069 13.0 0.6 0.15 12.0 0.6 1.6 1 0 0 1 1 1 0 F-box-like Alpha_kinase PF02816.18 KIK32428.1 - 3.3e-10 40.4 0.7 3.8e-10 40.2 0.7 1.0 1 0 0 1 1 1 1 Alpha-kinase family AAA_16 PF13191.6 KIK32429.1 - 1.8e-07 31.7 0.1 5.9e-07 30.0 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK32429.1 - 3.2e-06 27.2 0.0 7.4e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 KIK32429.1 - 0.00017 21.6 0.0 0.00053 20.0 0.0 1.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA PF00004.29 KIK32429.1 - 0.0012 19.3 0.0 0.0043 17.5 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KIK32429.1 - 0.0072 16.3 0.1 0.27 11.1 0.0 2.8 3 0 0 3 3 3 1 Rad17 P-loop domain RNA_helicase PF00910.22 KIK32429.1 - 0.011 16.2 0.0 0.033 14.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_PrkA PF08298.11 KIK32429.1 - 0.024 13.5 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Parvo_NS1 PF01057.17 KIK32429.1 - 0.031 13.4 0.3 0.19 10.8 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 APS_kinase PF01583.20 KIK32429.1 - 0.037 13.9 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase PhoU PF01895.19 KIK32429.1 - 0.053 14.0 2.1 1.8 9.1 0.1 3.3 3 0 0 3 3 3 0 PhoU domain NB-ARC PF00931.22 KIK32429.1 - 0.063 12.5 0.0 0.15 11.2 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain PhoU_div PF01865.16 KIK32429.1 - 0.087 12.1 0.7 0.22 10.8 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF47 Asp5 PF17000.5 KIK32430.1 - 0.077 13.1 0.0 0.086 13.0 0.0 1.2 1 0 0 1 1 1 0 Accessory secretory protein Sec, Asp5 PNP_phzG_C PF10590.9 KIK32431.1 - 0.025 14.6 0.0 0.038 14.1 0.0 1.4 1 1 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region MIF4G PF02854.19 KIK32433.1 - 0.067 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 MIF4G domain GAS PF13851.6 KIK32433.1 - 0.58 9.5 5.8 0.064 12.6 1.3 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Plavaka PF18759.1 KIK32434.1 - 8.4e-33 114.0 0.0 1.2e-32 113.5 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase AA_permease_2 PF13520.6 KIK32436.1 - 1.4e-64 218.5 50.9 1.8e-64 218.2 50.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK32436.1 - 1e-17 64.0 45.4 1.5e-17 63.4 45.4 1.2 1 0 0 1 1 1 1 Amino acid permease Epiglycanin_C PF14654.6 KIK32436.1 - 0.36 10.9 3.2 0.2 11.7 0.3 2.1 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region ADPrib_exo_Tox PF03496.14 KIK32437.1 - 0.086 12.2 0.0 0.086 12.2 0.0 1.0 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme RT_RNaseH PF17917.1 KIK32438.1 - 0.0083 16.4 0.0 0.024 14.9 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase WD40 PF00400.32 KIK32439.1 - 8.6e-32 108.7 8.6 2.9e-09 37.4 0.2 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32439.1 - 2.4e-09 37.4 0.2 0.49 10.7 0.0 4.6 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK32439.1 - 3.7e-06 26.7 1.1 12 6.0 0.0 4.8 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK32439.1 - 0.0029 16.3 0.0 0.15 10.7 0.0 2.3 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK32439.1 - 0.012 14.6 0.1 2.1 7.2 0.0 2.9 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK32439.1 - 0.014 14.8 0.1 0.67 9.2 0.0 2.9 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK32439.1 - 0.035 13.4 0.0 2.8 7.2 0.0 2.7 3 0 0 3 3 3 0 WD40-like domain TRI5 PF06330.11 KIK32441.1 - 7.9e-09 34.8 1.9 1.3e-07 30.8 1.8 2.0 1 1 0 1 1 1 1 Trichodiene synthase (TRI5) Pkinase_Tyr PF07714.17 KIK32442.1 - 0.00038 19.8 0.0 0.00039 19.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK32442.1 - 0.004 16.6 0.0 0.0045 16.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Glyphos_transf PF04464.14 KIK32443.1 - 0.11 11.4 0.0 11 4.9 0.0 2.7 1 1 1 2 2 2 0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase DUF2374 PF09574.10 KIK32444.1 - 0.2 11.5 0.2 0.32 10.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) SNF2_N PF00176.23 KIK32445.1 - 0.003 16.3 0.0 0.0035 16.1 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.25 KIK32446.1 - 8.4e-12 45.0 0.0 1.2e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Bromodomain MIF4G PF02854.19 KIK32449.1 - 0.065 12.9 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 MIF4G domain Plavaka PF18759.1 KIK32451.1 - 8e-09 35.2 0.0 9e-09 35.0 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK32452.1 - 3.2e-15 56.2 0.1 4.2e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase ABC_tran PF00005.27 KIK32453.1 - 0.00034 21.1 0.0 0.025 15.1 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KIK32453.1 - 0.089 12.6 0.9 3.4 7.4 0.4 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Runt PF00853.19 KIK32453.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Runt domain Lysis_col PF02402.16 KIK32456.1 - 0.45 10.2 3.3 0.53 10.0 0.0 2.1 2 0 0 2 2 2 0 Lysis protein RhoGEF PF00621.20 KIK32458.1 - 1.7e-15 57.7 0.3 2.4e-15 57.2 0.3 1.2 1 0 0 1 1 1 1 RhoGEF domain AA_permease_2 PF13520.6 KIK32460.1 - 8.6e-62 209.3 40.7 1.1e-61 209.0 40.7 1.1 1 0 0 1 1 1 1 Amino acid permease CHAT PF12770.7 KIK32461.1 - 6.6e-33 114.3 0.0 2.2e-32 112.6 0.0 1.8 1 0 0 1 1 1 1 CHAT domain Surp PF01805.20 KIK32461.1 - 0.0039 17.1 0.0 0.0085 16.1 0.0 1.5 1 0 0 1 1 1 1 Surp module MIT PF04212.18 KIK32461.1 - 0.054 13.6 0.1 30 4.8 0.0 3.7 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 KIK32461.1 - 0.064 13.4 1.8 20 5.6 0.1 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIK32461.1 - 5.1 7.1 23.8 38 4.3 0.6 8.2 6 4 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIK32462.1 - 7.6e-07 29.3 0.4 0.16 12.3 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIK32462.1 - 5.1e-05 22.9 0.9 2.9 7.9 0.0 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIK32462.1 - 0.00034 20.4 8.2 12 5.9 0.4 5.5 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIK32462.1 - 0.00083 20.0 0.2 6 8.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK32462.1 - 0.0013 18.7 0.8 3.8 7.9 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK32462.1 - 0.0066 16.8 0.0 0.84 10.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Sel1 PF08238.12 KIK32462.1 - 0.027 15.1 0.0 6.3 7.6 0.0 3.0 3 0 0 3 3 3 0 Sel1 repeat MFS_1 PF07690.16 KIK32464.1 - 2.9e-18 65.9 56.6 2.8e-17 62.7 32.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_3 PF07969.11 KIK32466.1 - 0.00011 21.8 0.2 0.00029 20.4 0.2 1.7 2 0 0 2 2 2 1 Amidohydrolase family Retrotran_gag_2 PF14223.6 KIK32467.1 - 6.2e-11 42.1 0.0 8.4e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KIK32467.1 - 0.00061 19.4 0.0 0.00094 18.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 KIK32467.1 - 0.0022 17.8 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 KIK32468.1 - 4e-11 42.6 0.2 8.4e-11 41.6 0.1 1.7 2 0 0 2 2 2 1 GAG-pre-integrase domain Sec23_helical PF04815.15 KIK32469.1 - 6.1e-16 58.1 0.1 1.2e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_trunk PF04811.15 KIK32469.1 - 3.6e-11 43.1 0.0 5.3e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Gelsolin PF00626.22 KIK32469.1 - 0.06 13.3 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Gelsolin repeat Cwf_Cwc_15 PF04889.12 KIK32471.1 - 0.041 13.6 5.7 0.056 13.2 5.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CxC5 PF18718.1 KIK32472.1 - 4.2e-32 110.7 5.1 6.6e-32 110.0 5.1 1.2 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases IBR PF01485.21 KIK32472.1 - 0.089 13.0 2.3 0.16 12.2 2.3 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Plavaka PF18759.1 KIK32473.1 - 3.5e-29 102.0 0.0 4.4e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase PB1 PF00564.24 KIK32474.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 PB1 domain PAS_4 PF08448.10 KIK32474.1 - 0.12 12.6 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 PAS fold zf-C2HC_2 PF13913.6 KIK32475.1 - 4.8e-05 23.1 3.9 7e-05 22.6 3.9 1.2 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-Di19 PF05605.12 KIK32475.1 - 0.019 15.3 0.5 0.028 14.7 0.5 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Nairovirus_M PF07948.11 KIK32475.1 - 0.029 12.6 0.0 0.033 12.4 0.0 1.0 1 0 0 1 1 1 0 Nairovirus M polyprotein-like zf-C2H2_4 PF13894.6 KIK32475.1 - 0.068 14.0 3.2 0.15 13.0 3.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zinc_ribbon_4 PF13717.6 KIK32475.1 - 0.31 11.0 3.1 0.58 10.1 0.5 2.5 2 1 0 2 2 2 0 zinc-ribbon domain WD40 PF00400.32 KIK32476.1 - 4.1e-19 68.6 26.4 5.8e-08 33.3 3.2 7.2 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32476.1 - 1.6e-13 50.7 1.2 0.00073 19.8 0.1 6.6 1 1 6 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK32476.1 - 9.6e-07 28.1 0.1 0.25 10.2 0.0 3.5 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK32476.1 - 3.1e-06 26.1 0.9 0.2 10.3 0.1 4.7 3 2 2 5 5 5 2 Nucleoporin Nup120/160 PD40 PF07676.12 KIK32476.1 - 0.00038 20.3 0.7 13 5.8 0.1 5.0 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK32476.1 - 0.00042 19.8 0.3 0.37 10.1 0.0 3.7 2 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PQQ PF01011.21 KIK32476.1 - 0.0025 17.7 0.3 9.1 6.4 0.0 4.3 4 0 0 4 4 4 1 PQQ enzyme repeat PQQ_3 PF13570.6 KIK32476.1 - 0.0049 17.3 0.8 4.7 7.8 1.4 3.7 3 1 0 3 3 3 1 PQQ-like domain DUF5046 PF16465.5 KIK32476.1 - 0.013 15.0 0.0 0.18 11.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5046) DUF1481 PF07356.12 KIK32477.1 - 0.0099 15.7 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1481) Plavaka PF18759.1 KIK32479.1 - 1.9e-74 250.8 3.2 1.2e-72 244.9 3.2 2.2 1 1 0 1 1 1 1 Plavaka transposase zf-C2H2 PF00096.26 KIK32479.1 - 0.059 13.9 0.7 0.22 12.0 0.7 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type PAS_9 PF13426.7 KIK32481.1 - 7.3e-24 84.0 0.0 6e-14 52.2 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS PF00989.25 KIK32481.1 - 1.3e-18 67.0 0.0 3.4e-07 30.3 0.0 3.9 4 0 0 4 4 4 3 PAS fold PAS_3 PF08447.12 KIK32481.1 - 3.8e-17 62.3 0.1 1.1e-06 28.8 0.0 4.7 5 0 0 5 5 5 4 PAS fold PAS_4 PF08448.10 KIK32481.1 - 5.9e-11 42.6 0.1 0.00056 20.1 0.0 3.7 4 0 0 4 4 4 2 PAS fold PAS_11 PF14598.6 KIK32481.1 - 3e-05 24.1 0.0 0.00015 21.9 0.0 2.2 2 1 0 2 2 2 1 PAS domain PAS_8 PF13188.7 KIK32481.1 - 6.9e-05 22.8 0.0 0.31 11.1 0.0 3.5 4 0 0 4 4 4 2 PAS domain Cas_Csn2 PF09711.10 KIK32485.1 - 0.076 12.7 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csn2) WD40 PF00400.32 KIK32487.1 - 2.1e-21 75.8 3.7 2.7e-07 31.2 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32487.1 - 5.4e-08 33.0 0.0 0.017 15.4 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK32487.1 - 0.00044 19.3 0.2 0.51 9.2 0.0 2.2 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK32487.1 - 0.0025 16.5 0.0 0.85 8.2 0.0 2.6 2 1 0 2 2 2 2 Nucleoporin Nup120/160 KDZ PF18758.1 KIK32492.1 - 6.8e-76 254.8 0.0 1e-75 254.2 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase WD40 PF00400.32 KIK32493.1 - 4.3e-09 36.9 0.0 5.2e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32493.1 - 0.002 18.4 0.0 0.002 18.4 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK32493.1 - 0.094 11.7 0.0 0.096 11.6 0.0 1.0 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Asp_protease_2 PF13650.6 KIK32494.1 - 5.1e-05 23.8 0.0 0.00036 21.1 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK32494.1 - 0.0012 19.3 0.0 0.0041 17.6 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease SLT_L PF14718.6 KIK32494.1 - 0.058 13.5 0.1 2.4 8.3 0.0 2.8 2 0 0 2 2 2 0 Soluble lytic murein transglycosylase L domain Med3 PF11593.8 KIK32494.1 - 0.58 9.3 4.8 0.85 8.7 4.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MFS_1 PF07690.16 KIK32496.1 - 6.8e-16 58.1 16.0 8.1e-16 57.9 16.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK32496.1 - 1.7e-06 27.2 2.5 2.1e-06 26.9 2.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4131 PF13567.6 KIK32496.1 - 2.5 7.7 8.0 13 5.4 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Adaptin_binding PF10199.9 KIK32498.1 - 3 8.4 14.0 7.3 7.2 13.2 2.0 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 STAC2_u1 PF16664.5 KIK32498.1 - 5.9 7.4 13.4 0.84 10.1 4.6 2.5 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Plavaka PF18759.1 KIK32499.1 - 1.4e-119 399.1 0.0 1.8e-119 398.7 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase WD40 PF00400.32 KIK32500.1 - 3.7e-13 49.7 1.8 2.5e-12 47.1 0.1 2.0 2 0 0 2 2 2 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KIK32500.1 - 0.00035 19.6 0.0 0.00037 19.6 0.0 1.0 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KIK32500.1 - 0.0022 18.2 0.0 0.0024 18.1 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK32500.1 - 0.035 14.1 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Gln-synt_C PF00120.24 KIK32502.1 - 9.8e-26 90.6 0.0 1.2e-25 90.3 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Retrotran_gag_2 PF14223.6 KIK32504.1 - 1.5e-07 31.1 0.0 2.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KIK32504.1 - 0.013 15.5 1.3 0.013 15.5 1.3 2.4 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 KIK32504.1 - 2 8.2 9.4 5.2 6.9 2.3 2.8 2 1 1 3 3 3 0 Zinc knuckle AlgF PF11182.8 KIK32505.1 - 0.079 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF DUF1192 PF06698.11 KIK32505.1 - 0.76 9.9 5.3 0.21 11.6 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) 40S_SA_C PF16122.5 KIK32507.1 - 1.1 10.7 6.1 2.6 9.5 3.0 2.7 2 1 0 2 2 2 0 40S ribosomal protein SA C-terminus Plavaka PF18759.1 KIK32509.1 - 4.1e-12 46.0 0.0 5.3e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase gag-asp_proteas PF13975.6 KIK32510.1 - 4.5e-07 30.4 0.1 7.6e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIK32510.1 - 1.4e-06 28.9 0.1 2.1e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KIK32510.1 - 2.5e-05 24.1 0.0 3.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 KIK32510.1 - 0.01 15.9 0.3 0.017 15.2 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Cu-oxidase_2 PF07731.14 KIK32512.1 - 5.4e-38 129.8 0.3 1.5e-37 128.4 0.1 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KIK32512.1 - 5.4e-35 120.9 0.1 6.4e-31 107.6 0.0 2.2 2 0 0 2 2 2 2 Multicopper oxidase UPF0193 PF05250.11 KIK32514.1 - 0.13 12.0 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) TPR_10 PF13374.6 KIK32515.1 - 3.9e-15 55.2 9.5 0.012 15.5 0.0 7.6 7 1 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 KIK32515.1 - 4.7e-07 30.0 9.9 0.14 12.5 0.0 7.4 3 2 5 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK32515.1 - 6.5e-06 25.7 0.6 3.3 7.7 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK32515.1 - 0.00011 21.9 10.0 4 7.7 0.0 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK32515.1 - 0.00038 21.0 10.4 72 4.6 0.0 8.0 7 2 1 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK32515.1 - 0.0026 17.8 6.6 13 6.2 0.0 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat MIT PF04212.18 KIK32515.1 - 0.014 15.4 0.2 31 4.7 0.1 4.7 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF3563 PF12086.8 KIK32515.1 - 0.41 10.4 2.6 0.78 9.5 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3563) Vta1_C PF18097.1 KIK32515.1 - 0.44 10.3 8.6 0.46 10.2 0.1 4.2 4 0 0 4 4 4 0 Vta1 C-terminal domain UPF0020 PF01170.18 KIK32518.1 - 6.3e-10 39.1 0.0 2e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 KIK32518.1 - 0.012 15.3 0.0 2.5 7.7 0.0 2.5 2 1 0 2 2 2 0 DNA methylase N6_Mtase PF02384.16 KIK32518.1 - 0.061 12.6 0.0 0.2 10.9 0.0 1.8 2 1 0 2 2 2 0 N-6 DNA Methylase DEAD PF00270.29 KIK32520.1 - 0.087 12.6 0.1 0.091 12.5 0.1 1.0 1 0 0 1 1 1 0 DEAD/DEAH box helicase Zn_clus PF00172.18 KIK32521.1 - 0.83 9.8 7.8 6.3 7.0 3.1 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Transposase_21 PF02992.14 KIK32524.1 - 6.1e-08 32.2 0.0 7.1e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 Plavaka PF18759.1 KIK32524.1 - 1.6e-05 24.3 0.3 2e-05 24.0 0.3 1.0 1 0 0 1 1 1 1 Plavaka transposase Titin_Z PF09042.11 KIK32526.1 - 0.64 10.0 3.5 0.48 10.4 0.3 2.3 2 1 0 2 2 2 0 Titin Z Plavaka PF18759.1 KIK32527.1 - 2e-97 326.4 0.0 2.9e-97 325.8 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Tet_JBP PF12851.7 KIK32528.1 - 0.001 18.5 0.0 0.0013 18.2 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily WD40 PF00400.32 KIK32529.1 - 3.3e-18 65.7 21.9 2.9e-08 34.2 3.5 5.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32529.1 - 3.1e-15 56.2 0.5 0.012 15.9 0.0 5.4 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK32529.1 - 0.0001 21.1 2.1 0.2 10.2 0.1 3.1 1 1 2 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK32529.1 - 0.00031 20.2 0.0 0.0043 16.4 0.0 2.4 1 1 2 3 3 3 1 WD40-like domain PQQ PF01011.21 KIK32529.1 - 0.0023 17.8 0.3 4.1 7.5 0.0 3.8 3 0 0 3 3 3 1 PQQ enzyme repeat Nbas_N PF15492.6 KIK32529.1 - 0.0031 16.9 1.4 4.4 6.6 0.1 3.5 2 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PQQ_3 PF13570.6 KIK32529.1 - 0.0084 16.6 6.0 1.3 9.6 1.6 4.0 3 1 1 4 4 4 1 PQQ-like domain PD40 PF07676.12 KIK32529.1 - 0.083 12.8 3.3 1.4e+02 2.6 0.0 5.3 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK32529.1 - 0.12 10.7 0.0 0.23 9.7 0.0 1.4 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Plavaka PF18759.1 KIK32535.1 - 6.5e-130 433.1 0.0 8.8e-130 432.7 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase WD40 PF00400.32 KIK32536.1 - 2.3e-113 366.9 53.3 2e-09 37.9 0.1 13.8 13 0 0 13 13 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32536.1 - 5.9e-27 93.8 11.2 0.04 14.2 0.0 11.8 1 1 12 13 13 13 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK32536.1 - 1.8e-15 56.7 5.7 0.35 9.8 0.0 9.6 2 2 7 11 11 11 5 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK32536.1 - 4.2e-12 45.7 13.6 2.4 8.2 0.0 10.3 12 0 0 12 12 12 3 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 KIK32536.1 - 5.1e-12 45.3 12.0 0.029 13.1 1.2 8.5 1 1 6 7 7 7 5 Nup133 N terminal like WD40_like PF17005.5 KIK32536.1 - 1.5e-11 44.2 0.4 0.15 11.3 0.0 8.0 7 3 2 9 9 9 3 WD40-like domain Nup160 PF11715.8 KIK32536.1 - 7.2e-11 41.4 11.1 1.6 7.3 0.0 11.1 9 3 4 13 13 13 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KIK32536.1 - 3.8e-09 36.8 11.4 4 8.0 0.1 9.8 8 4 3 11 11 11 2 PQQ-like domain BBS2_Mid PF14783.6 KIK32536.1 - 9.1e-09 35.3 5.4 1.6 8.8 0.0 10.5 13 0 0 13 13 13 1 Ciliary BBSome complex subunit 2, middle region DUF4402 PF14352.6 KIK32536.1 - 6.7e-08 33.2 14.9 0.67 10.6 0.2 6.3 1 1 3 6 6 6 4 Domain of unknown function (DUF4402) Frtz PF11768.8 KIK32536.1 - 6.6e-05 21.4 0.0 0.84 7.9 0.0 5.5 3 2 4 7 7 7 1 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 KIK32536.1 - 0.00036 20.0 2.1 0.3 10.4 0.0 5.2 4 1 2 6 6 6 1 Neuroblastoma-amplified sequence, N terminal PQQ PF01011.21 KIK32536.1 - 0.0081 16.1 0.0 1.3e+02 2.7 0.0 6.3 8 0 0 8 8 8 0 PQQ enzyme repeat DUF4393 PF14337.6 KIK32536.1 - 0.16 11.7 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) Cuticle_4 PF15955.5 KIK32536.1 - 3.2 8.5 22.3 49 4.7 0.0 8.4 10 1 0 11 11 9 0 Cuticle protein Retrotran_gag_2 PF14223.6 KIK32537.1 - 2.4e-16 59.7 0.0 2.9e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1451 PF07295.11 KIK32537.1 - 0.11 12.6 0.2 0.22 11.5 0.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain p450 PF00067.22 KIK32539.1 - 1.7e-11 43.6 0.0 1.8e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 V_ATPase_I PF01496.19 KIK32540.1 - 3.9e-08 31.7 0.7 5.4e-05 21.3 0.2 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family Dimer_Tnp_hAT PF05699.14 KIK32541.1 - 2.5e-08 33.6 0.3 3e-08 33.3 0.3 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF2829 PF11195.8 KIK32541.1 - 0.099 12.9 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2829) DUF4413 PF14372.6 KIK32542.1 - 0.037 14.4 0.0 0.041 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) OrsD PF12013.8 KIK32546.1 - 4.8e-08 33.4 1.5 2.2e-07 31.3 1.5 2.3 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D DEAD PF00270.29 KIK32546.1 - 3.9e-05 23.5 0.0 0.0001 22.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIK32546.1 - 0.027 14.5 0.0 0.069 13.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PSK_trans_fac PF07704.11 KIK32546.1 - 1.3 9.9 4.0 1.1 10.1 0.2 2.8 2 0 0 2 2 2 0 Rv0623-like transcription factor zf-C2H2_4 PF13894.6 KIK32546.1 - 7.1 7.8 6.8 9.6 7.3 1.7 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger WD40 PF00400.32 KIK32547.1 - 1.7e-44 148.9 31.5 2.9e-07 31.1 2.2 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32547.1 - 1.4e-20 73.4 6.3 8.6e-05 22.8 0.2 6.3 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK32547.1 - 1.5e-09 37.3 0.0 0.029 13.3 0.0 5.7 1 1 6 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK32547.1 - 1.7e-07 30.9 3.7 0.31 10.3 0.1 4.9 1 1 5 6 6 6 3 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK32547.1 - 2e-07 30.0 0.1 0.68 8.5 0.0 4.9 4 1 1 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK32547.1 - 1.9e-06 27.9 0.1 0.2 11.5 0.0 3.8 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK32547.1 - 7.3e-05 22.6 1.0 7.3 6.7 0.0 4.7 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK32547.1 - 0.0001 20.8 0.0 0.25 9.6 0.0 3.2 2 1 1 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK32547.1 - 0.00019 20.9 0.0 1.2 8.4 0.0 3.1 3 1 1 4 4 4 2 WD40-like domain PQQ_3 PF13570.6 KIK32547.1 - 0.00055 20.3 4.4 12 6.5 0.0 5.9 6 0 0 6 6 6 1 PQQ-like domain Cytochrom_D1 PF02239.16 KIK32547.1 - 0.00062 18.4 0.1 1.1 7.8 0.0 3.0 2 2 2 4 4 4 2 Cytochrome D1 heme domain RAB3GAP2_N PF14655.6 KIK32547.1 - 0.051 12.8 1.0 3.4 6.8 0.1 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Arena_nucleocap PF00843.17 KIK32547.1 - 0.073 12.0 4.1 11 4.8 0.1 3.9 2 2 2 4 4 4 0 Arenavirus nucleocapsid N-terminal domain DUF1090 PF06476.12 KIK32549.1 - 0.14 12.3 2.6 0.23 11.6 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) CxC2 PF18803.1 KIK32550.1 - 1.7e-34 118.2 0.9 3e-34 117.4 0.9 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK32550.1 - 1.4e-05 25.2 0.5 2.6e-05 24.3 0.5 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Sds3 PF08598.11 KIK32550.1 - 0.012 15.6 1.2 0.018 15.1 1.2 1.2 1 0 0 1 1 1 0 Sds3-like Enkurin PF13864.6 KIK32550.1 - 0.061 13.8 3.0 0.45 11.0 0.3 2.7 3 0 0 3 3 3 0 Calmodulin-binding RVT_2 PF07727.14 KIK32554.1 - 0.073 12.7 0.0 0.084 12.5 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Helitron_like_N PF14214.6 KIK32555.1 - 1.4e-27 97.2 0.6 1.4e-27 97.2 0.6 2.7 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus DUF416 PF04222.12 KIK32555.1 - 0.022 14.2 1.5 0.13 11.7 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF416) AAA PF00004.29 KIK32556.1 - 3.2e-09 37.3 0.0 5.2e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) WD40 PF00400.32 KIK32556.1 - 7e-06 26.7 1.1 9e-05 23.2 0.4 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat Carn_acyltransf PF00755.20 KIK32557.1 - 2.1e-10 39.9 0.0 2.2e-10 39.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Npa1 PF11707.8 KIK32563.1 - 6.6e-14 52.0 0.0 6.7e-10 38.8 0.0 2.2 1 1 1 2 2 2 2 Ribosome 60S biogenesis N-terminal Sugar_tr PF00083.24 KIK32568.1 - 0.022 13.6 0.2 0.022 13.6 0.2 1.7 2 0 0 2 2 2 0 Sugar (and other) transporter RVT_1 PF00078.27 KIK32570.1 - 0.051 13.1 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) AA_permease PF00324.21 KIK32579.1 - 9e-114 380.7 43.9 1.1e-113 380.4 43.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK32579.1 - 1.3e-41 142.9 44.9 1.7e-41 142.4 44.9 1.1 1 0 0 1 1 1 1 Amino acid permease Spt4 PF06093.13 KIK32580.1 - 0.019 15.0 0.7 0.019 15.0 0.7 1.5 1 1 1 2 2 2 0 Spt4/RpoE2 zinc finger DUF4637 PF15470.6 KIK32580.1 - 0.094 12.4 0.9 0.099 12.4 0.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4637) Pyridoxal_deC PF00282.19 KIK32583.1 - 9.3e-16 57.5 0.0 1.7e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KIK32583.1 - 1.6e-08 33.9 0.0 0.00014 21.0 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KIK32583.1 - 0.00012 21.6 0.1 0.00018 20.9 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Prefoldin_2 PF01920.20 KIK32584.1 - 1.6e-19 69.8 5.2 1.9e-19 69.6 5.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit MIF4G_like_2 PF09090.11 KIK32584.1 - 0.032 13.7 1.8 0.038 13.5 1.8 1.1 1 0 0 1 1 1 0 MIF4G like Prefoldin PF02996.17 KIK32584.1 - 0.037 13.9 1.2 0.037 13.9 1.2 2.1 1 1 1 2 2 2 0 Prefoldin subunit DivIC PF04977.15 KIK32584.1 - 0.044 13.6 7.8 1.6 8.6 2.6 2.2 1 1 1 2 2 2 0 Septum formation initiator Katanin_con80 PF13925.6 KIK32584.1 - 0.05 13.7 0.3 0.09 12.8 0.3 1.4 1 0 0 1 1 1 0 con80 domain of Katanin Spc24 PF08286.11 KIK32584.1 - 0.053 13.8 7.3 0.71 10.1 3.1 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Laminin_II PF06009.12 KIK32584.1 - 0.068 13.2 2.4 0.085 12.9 0.5 1.9 2 0 0 2 2 2 0 Laminin Domain II BLOC1_2 PF10046.9 KIK32584.1 - 0.085 13.2 5.6 0.15 12.4 2.7 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MAP65_ASE1 PF03999.12 KIK32584.1 - 0.094 11.4 6.5 0.1 11.3 6.5 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) YabA PF06156.13 KIK32584.1 - 0.11 13.1 1.8 2.4 8.8 0.4 2.2 2 0 0 2 2 2 0 Initiation control protein YabA FlxA PF14282.6 KIK32584.1 - 0.12 12.3 4.0 7.9 6.5 0.1 2.3 2 0 0 2 2 2 0 FlxA-like protein V_ATPase_I PF01496.19 KIK32584.1 - 0.2 9.5 3.6 0.25 9.2 3.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FTA4 PF13093.6 KIK32584.1 - 0.29 11.0 5.5 0.42 10.5 5.5 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 FapA PF03961.13 KIK32584.1 - 0.33 9.5 2.4 0.39 9.3 2.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A PCRF PF03462.18 KIK32584.1 - 0.34 10.7 7.0 0.64 9.8 7.0 1.5 1 1 0 1 1 1 0 PCRF domain DUF2312 PF10073.9 KIK32584.1 - 0.4 10.4 6.3 0.32 10.7 1.7 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Helo_like_N PF17111.5 KIK32584.1 - 0.46 9.8 7.7 0.11 11.8 3.0 1.9 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins DASH_Dam1 PF08653.10 KIK32584.1 - 0.62 9.9 2.0 1.4 8.8 0.6 2.1 2 0 0 2 2 2 0 DASH complex subunit Dam1 XhlA PF10779.9 KIK32584.1 - 0.66 10.2 4.2 0.68 10.2 1.1 2.1 2 0 0 2 2 2 0 Haemolysin XhlA bZIP_1 PF00170.21 KIK32584.1 - 1.1 9.4 10.4 4.3 7.5 2.3 2.4 2 0 0 2 2 2 0 bZIP transcription factor DUF4140 PF13600.6 KIK32584.1 - 1.4 9.4 6.8 0.46 10.9 2.1 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) UPF0449 PF15136.6 KIK32584.1 - 5.5 7.5 9.3 1.4 9.4 3.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 DUF1604 PF07713.13 KIK32585.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) WD40 PF00400.32 KIK32587.1 - 1.7e-07 31.8 8.0 0.00044 21.0 0.2 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32587.1 - 0.00016 21.9 0.1 3.7 7.9 0.0 3.2 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK32588.1 - 2.7e-16 59.7 7.4 2.7e-08 34.3 2.5 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32588.1 - 6.4e-10 39.2 0.7 0.00044 20.5 0.1 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK32588.1 - 0.00043 19.3 0.1 0.0039 16.2 0.1 1.9 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK32588.1 - 0.00078 19.3 0.4 3.1 7.8 0.0 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK32588.1 - 0.0015 17.9 0.3 0.014 14.7 0.0 2.1 1 1 1 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK32588.1 - 0.0024 16.6 1.2 0.099 11.3 0.4 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK32588.1 - 0.047 13.6 0.1 0.06 13.2 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A CHAP PF05257.16 KIK32588.1 - 0.052 14.1 0.5 0.066 13.8 0.5 1.3 1 0 0 1 1 1 0 CHAP domain DUF1264 PF06884.11 KIK32588.1 - 0.073 12.7 0.1 0.11 12.1 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1264) DUF3845 PF12956.7 KIK32588.1 - 0.099 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure Proteasom_PSMB PF10508.9 KIK32590.1 - 0.0094 14.5 0.1 0.011 14.3 0.1 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit PhoLip_ATPase_C PF16212.5 KIK32591.1 - 3.5e-41 141.6 25.5 4.1e-41 141.4 25.5 1.0 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal RVP_2 PF08284.11 KIK32594.1 - 6.7e-12 45.3 0.1 7.3e-12 45.2 0.1 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KIK32594.1 - 1.1e-07 32.3 0.0 1.2e-07 32.1 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIK32594.1 - 1.4e-05 25.6 0.0 1.7e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KIK32594.1 - 0.033 14.0 0.1 0.045 13.5 0.1 1.2 1 0 0 1 1 1 0 Aspartyl protease ATG11 PF10377.9 KIK32595.1 - 0.0041 17.2 0.0 0.0053 16.8 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 11 MOR2-PAG1_C PF14225.6 KIK32595.1 - 0.035 14.0 0.1 0.046 13.6 0.1 1.1 1 0 0 1 1 1 0 Cell morphogenesis C-terminal rve PF00665.26 KIK32596.1 - 6.5e-08 32.8 0.0 8.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KIK32596.1 - 0.00023 20.9 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KIK32597.1 - 0.1 12.8 0.4 0.32 11.1 0.0 2.1 3 0 0 3 3 3 0 Integrase zinc binding domain FlgM PF04316.13 KIK32599.1 - 0.08 13.3 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM gag-asp_proteas PF13975.6 KIK32600.1 - 0.00011 22.6 0.0 0.00012 22.5 0.0 1.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIK32600.1 - 0.0006 20.4 0.0 0.00067 20.2 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KIK32600.1 - 0.0089 16.3 0.0 0.01 16.1 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 KIK32600.1 - 0.017 14.6 0.0 0.019 14.5 0.0 1.0 1 0 0 1 1 1 0 Ty3 transposon peptidase WD40 PF00400.32 KIK32601.1 - 6.2e-27 93.3 16.3 3e-08 34.2 3.2 6.6 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32601.1 - 9.1e-20 70.8 2.3 8.4e-06 26.0 0.3 6.0 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK32601.1 - 8.5e-09 34.8 0.1 0.011 14.8 0.0 3.8 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK32601.1 - 1.8e-06 28.0 0.1 0.0023 17.9 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK32601.1 - 1.8e-06 26.9 2.4 0.69 8.5 0.1 4.5 2 2 3 5 5 5 3 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK32601.1 - 2.5e-06 27.0 0.9 0.036 13.4 0.0 4.5 1 1 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 KIK32601.1 - 3e-06 26.0 0.3 0.0023 16.6 0.0 2.8 2 2 2 4 4 4 2 Cytochrome D1 heme domain PD40 PF07676.12 KIK32601.1 - 3.9e-06 26.7 0.0 16 5.5 0.0 6.3 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK32601.1 - 0.00035 20.0 0.0 0.0044 16.4 0.0 2.1 2 0 0 2 2 2 1 WD40-like domain PQQ_3 PF13570.6 KIK32601.1 - 0.0017 18.8 4.1 0.53 10.8 2.2 3.1 3 0 0 3 3 3 1 PQQ-like domain Nucleoporin_N PF08801.11 KIK32601.1 - 0.0053 15.6 0.1 0.023 13.5 0.0 1.9 2 1 0 2 2 2 1 Nup133 N terminal like RAB3GAP2_N PF14655.6 KIK32601.1 - 0.037 13.3 0.1 0.15 11.3 0.1 2.0 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Hira PF07569.11 KIK32601.1 - 0.067 12.9 0.0 13 5.4 0.0 2.5 2 0 0 2 2 2 0 TUP1-like enhancer of split IRF PF00605.17 KIK32601.1 - 0.13 12.5 0.0 14 6.0 0.0 2.3 1 1 1 2 2 2 0 Interferon regulatory factor transcription factor WD40 PF00400.32 KIK32603.1 - 0.012 16.4 0.1 0.027 15.3 0.1 1.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KIK32603.1 - 0.11 11.4 0.0 0.11 11.4 0.0 1.0 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_5 PF07728.14 KIK32604.1 - 1e-26 93.6 0.0 9.8e-17 61.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KIK32604.1 - 2.6e-08 33.8 0.0 4.4e-06 26.6 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_7 PF17867.1 KIK32604.1 - 3.1e-08 33.8 0.2 6.9e-08 32.6 0.2 1.6 1 0 0 1 1 1 1 Midasin AAA lid domain AAA PF00004.29 KIK32604.1 - 2.2e-07 31.4 0.0 0.0067 16.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK32604.1 - 1.3e-05 25.5 0.4 0.0036 17.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KIK32604.1 - 3.4e-05 23.5 0.0 0.00037 20.1 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_6 PF12774.7 KIK32604.1 - 3.7e-05 22.9 0.0 0.1 11.6 0.0 2.6 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region AAA_16 PF13191.6 KIK32604.1 - 6.5e-05 23.4 5.0 0.011 16.1 0.1 3.4 2 1 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 KIK32604.1 - 0.0013 19.3 0.0 0.7 10.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KIK32604.1 - 0.004 17.4 0.7 1.3 9.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 KIK32604.1 - 0.0044 16.7 0.0 0.043 13.5 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain TsaE PF02367.17 KIK32604.1 - 0.015 15.3 0.0 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KIK32604.1 - 0.037 14.5 0.0 0.67 10.5 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Dynein_heavy PF03028.15 KIK32604.1 - 0.058 13.5 0.0 0.21 11.7 0.0 1.9 2 0 0 2 2 1 0 Dynein heavy chain region D6 P-loop domain RNA_helicase PF00910.22 KIK32604.1 - 0.062 13.7 0.0 2.8 8.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 KIK32604.1 - 0.074 12.4 0.2 17 4.7 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 KIK32604.1 - 0.098 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 KIK32604.1 - 0.12 12.1 0.0 3.1 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KIK32604.1 - 0.12 11.4 0.0 1.2 8.2 0.1 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein IPT PF01745.16 KIK32604.1 - 0.14 11.5 0.0 16 4.8 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase WD40 PF00400.32 KIK32605.1 - 2.1e-17 63.1 21.8 2.4e-09 37.7 1.9 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32605.1 - 7.2e-13 48.6 3.3 0.012 15.9 0.3 5.6 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK32605.1 - 1.4e-05 24.9 0.1 20 5.2 0.0 5.6 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KIK32605.1 - 4.2e-05 23.5 1.6 0.067 13.1 0.3 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK32605.1 - 6.8e-05 22.0 0.0 0.036 13.0 0.0 3.1 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 KIK32605.1 - 0.0003 20.6 0.2 0.4 10.7 0.0 4.3 3 1 1 4 4 4 1 PQQ enzyme repeat Nbas_N PF15492.6 KIK32605.1 - 0.00035 20.0 0.6 0.035 13.4 0.1 3.2 2 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.11 KIK32605.1 - 0.0015 17.7 0.3 0.015 14.4 0.0 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF1513) Nup160 PF11715.8 KIK32605.1 - 0.0052 15.5 5.2 0.51 8.9 0.1 3.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Lactonase PF10282.9 KIK32605.1 - 0.033 13.4 0.0 2.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Glycoprot_B_PH1 PF17416.2 KIK32607.1 - 0.23 11.0 0.0 0.25 10.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B WD40 PF00400.32 KIK32608.1 - 4.3e-29 100.1 19.3 7.3e-07 29.8 0.5 7.3 6 1 1 7 7 7 5 WD domain, G-beta repeat HET PF06985.11 KIK32608.1 - 1e-09 38.9 2.6 1.4e-07 31.9 0.1 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ANAPC4_WD40 PF12894.7 KIK32608.1 - 1e-07 32.1 0.0 1.1 9.6 0.0 5.0 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_1 PF00515.28 KIK32608.1 - 1.4e-05 24.7 0.7 0.072 13.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK32608.1 - 8.8e-05 23.0 2.6 4.2 8.5 0.1 4.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK32608.1 - 0.00018 21.4 1.5 0.034 14.3 0.1 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK32608.1 - 0.00021 21.1 3.1 5 7.4 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat Ge1_WD40 PF16529.5 KIK32608.1 - 0.00066 18.7 0.0 0.089 11.7 0.0 2.7 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_11 PF13414.6 KIK32608.1 - 0.002 17.8 0.1 0.027 14.1 0.0 2.4 2 0 0 2 2 2 1 TPR repeat eIF2A PF08662.11 KIK32608.1 - 0.0023 17.8 0.3 2.2 8.1 0.0 3.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A TPR_16 PF13432.6 KIK32608.1 - 0.059 14.0 3.7 1.3 9.7 0.2 3.0 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK32608.1 - 0.06 13.9 2.3 22 5.7 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK32608.1 - 0.078 13.2 0.2 0.86 10.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 KIK32608.1 - 0.095 12.7 0.7 20 5.3 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIK32608.1 - 1.8 8.9 7.9 6.3 7.2 0.6 3.4 3 1 1 4 4 3 0 Tetratricopeptide repeat TauD PF02668.16 KIK32611.1 - 3.9e-07 30.1 0.0 7.2e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cyclin_N PF00134.23 KIK32612.1 - 3.5e-10 39.7 0.1 4.8e-08 32.8 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KIK32612.1 - 0.03 14.7 0.0 0.079 13.4 0.0 1.8 1 0 0 1 1 1 0 Cyclin C-terminal domain Npa1 PF11707.8 KIK32613.1 - 0.00017 21.1 0.0 0.00022 20.7 0.0 1.1 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal MTHFR_C PF12225.8 KIK32614.1 - 0.71 9.6 4.8 1.3 8.7 3.6 2.0 2 1 0 2 2 2 0 Methylene-tetrahydrofolate reductase C terminal RVT_thumb PF06817.14 KIK32616.1 - 0.0089 15.8 0.0 0.034 14.0 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase thumb domain zf-CCHC_4 PF14392.6 KIK32617.1 - 0.017 14.8 1.9 0.043 13.5 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 KIK32617.1 - 0.022 14.8 8.0 0.022 14.8 2.0 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 KIK32617.1 - 1.6 8.6 14.2 0.31 10.9 3.8 2.5 1 1 1 2 2 2 0 Zinc knuckle HTH_21 PF13276.6 KIK32618.1 - 0.027 14.6 0.2 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 HTH-like domain PYRIN PF02758.16 KIK32618.1 - 0.093 12.9 0.1 0.24 11.5 0.1 1.8 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain Alpha_kinase PF02816.18 KIK32619.1 - 7.4e-11 42.5 0.1 1.3e-10 41.8 0.1 1.5 1 1 0 1 1 1 1 Alpha-kinase family WD40 PF00400.32 KIK32625.1 - 1.6e-23 82.5 19.8 1e-05 26.1 3.6 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32625.1 - 2e-14 53.6 2.7 0.002 18.4 0.1 5.7 1 1 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK32625.1 - 0.00019 20.5 0.5 0.66 8.9 0.1 3.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK32625.1 - 0.0037 16.6 1.6 2 7.7 0.0 3.7 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK32625.1 - 0.0038 16.6 0.0 0.014 14.7 0.0 1.8 2 0 0 2 2 2 1 WD40-like domain PD40 PF07676.12 KIK32625.1 - 0.0059 16.5 1.8 1.2e+02 2.8 0.2 5.3 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK32625.1 - 0.045 12.4 3.5 5.9 5.4 0.1 3.7 2 1 2 4 4 4 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KIK32625.1 - 0.35 11.4 3.5 15 6.2 1.9 3.1 2 0 0 2 2 2 0 PQQ-like domain WD40 PF00400.32 KIK32627.1 - 1.2e-21 76.6 3.8 1e-11 45.2 0.1 2.0 2 0 0 2 2 2 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KIK32627.1 - 4.3e-07 29.2 0.0 0.0089 15.0 0.0 2.0 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KIK32627.1 - 6.8e-07 29.5 0.0 0.0089 16.3 0.0 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK32627.1 - 1.3e-05 25.0 0.1 0.18 11.8 0.0 2.3 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK32627.1 - 0.0079 14.9 0.1 0.25 9.9 0.0 2.0 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Frtz PF11768.8 KIK32627.1 - 0.028 12.7 0.0 0.34 9.2 0.0 1.9 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Ret2_MD PF18528.1 KIK32627.1 - 0.069 13.5 0.0 8.2 6.9 0.0 2.0 1 1 1 2 2 2 0 RNA editing 3' terminal uridylyl transferase 2 middle domain eIF2A PF08662.11 KIK32627.1 - 0.21 11.4 0.0 0.24 11.2 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK32627.1 - 0.25 10.6 0.0 3.2 7.0 0.0 1.9 1 1 1 2 2 2 0 WD40-like domain Proteasome_A_N PF10584.9 KIK32627.1 - 0.82 9.4 2.0 28 4.5 0.1 2.3 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature 2-Hacid_dh_C PF02826.19 KIK32630.1 - 0.1 11.9 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain VPR PF00522.18 KIK32632.1 - 0.033 14.2 0.0 0.039 14.0 0.0 1.1 1 0 0 1 1 1 0 VPR/VPX protein SipA_VBS PF17985.1 KIK32632.1 - 0.4 10.7 0.1 0.4 10.7 0.1 1.7 2 0 0 2 2 2 0 SipA vinculin binding site NodA PF02474.15 KIK32633.1 - 0.24 11.1 0.0 0.27 10.9 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein A (NodA) zf-UBP PF02148.19 KIK32637.1 - 0.086 13.2 0.2 0.33 11.3 0.0 1.9 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein KOW PF00467.29 KIK32638.1 - 0.095 12.7 1.2 10 6.2 0.2 2.3 2 0 0 2 2 2 0 KOW motif KOW PF00467.29 KIK32639.1 - 3.3e-09 36.4 0.7 2.3e-05 24.2 0.1 3.2 3 0 0 3 3 3 2 KOW motif Glyco_hydro_38 PF18438.1 KIK32641.1 - 0.066 13.3 0.0 2.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal domain 1 Plavaka PF18759.1 KIK32642.1 - 5.2e-93 311.8 1.1 8e-93 311.2 1.1 1.3 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2_4 PF13894.6 KIK32642.1 - 0.096 13.6 0.7 0.44 11.5 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger PBP1_TM PF14812.6 KIK32643.1 - 0.47 10.9 8.9 2.3 8.7 0.2 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1178 PF06676.11 KIK32645.1 - 0.73 10.2 4.6 2.1 8.7 4.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) NUDE_C PF04880.13 KIK32645.1 - 8.6 6.8 7.3 15 6.0 7.3 1.5 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region E1-E2_ATPase PF00122.20 KIK32648.1 - 9.6e-49 165.3 0.1 9.6e-49 165.3 0.1 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KIK32648.1 - 3e-38 131.4 0.7 3e-38 131.4 0.7 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KIK32648.1 - 2.5e-20 73.7 0.0 2.6e-19 70.4 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIK32648.1 - 1.1e-13 51.1 0.0 4.7e-13 49.0 0.0 2.1 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KIK32648.1 - 1.8e-09 37.1 0.1 4.9e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KIK32648.1 - 9e-05 22.3 1.3 0.0017 18.1 1.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.12 KIK32648.1 - 0.00033 20.6 0.5 0.0018 18.2 0.0 2.3 2 0 0 2 2 2 1 Positive regulator of sigma(E), RseC/MucC DMPK_coil PF08826.10 KIK32649.1 - 0.051 13.7 1.1 0.071 13.2 1.1 1.3 1 0 0 1 1 1 0 DMPK coiled coil domain like Plavaka PF18759.1 KIK32650.1 - 2.9e-88 296.2 0.1 4.1e-88 295.7 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2_9 PF16293.5 KIK32650.1 - 0.15 11.9 0.4 0.55 10.1 0.4 2.0 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) Pkinase_fungal PF17667.1 KIK32651.1 - 1.3e-12 47.2 0.0 1.6e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Ntox28 PF15605.6 KIK32651.1 - 0.17 12.1 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial toxin 28 WD40 PF00400.32 KIK32652.1 - 4.2e-43 144.5 26.0 2.7e-09 37.5 1.2 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32652.1 - 1.4e-20 73.4 3.2 5.7e-05 23.3 0.0 4.8 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK32652.1 - 5.2e-08 32.2 0.7 0.013 14.4 0.0 5.1 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK32652.1 - 7.4e-07 28.2 3.9 0.0021 16.8 0.6 3.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.12 KIK32652.1 - 4.3e-06 26.5 0.1 2.3 8.2 0.0 5.3 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK32652.1 - 3.4e-05 23.3 0.0 0.4 10.0 0.0 3.0 2 1 1 3 3 3 2 WD40-like domain Nucleoporin_N PF08801.11 KIK32652.1 - 0.0002 20.2 0.6 0.23 10.2 0.1 3.3 3 1 1 4 4 4 2 Nup133 N terminal like Nbas_N PF15492.6 KIK32652.1 - 0.0029 17.0 1.9 0.68 9.2 0.2 3.7 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal DUF5122 PF17164.4 KIK32652.1 - 0.073 13.4 0.2 22 5.4 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller Ceramidase_alk PF04734.13 KIK32652.1 - 0.093 11.3 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, N-terminal MMS1_N PF10433.9 KIK32652.1 - 0.12 11.0 0.0 0.17 10.4 0.0 1.4 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF5570 PF17731.1 KIK32652.1 - 0.3 11.2 3.1 1.6 8.8 0.1 3.0 3 1 1 4 4 4 0 Family of unknown function (DUF5570) PALB2_WD40 PF16756.5 KIK32652.1 - 0.44 9.4 6.6 0.74 8.7 0.3 2.9 1 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain RrnaAD PF00398.20 KIK32653.1 - 1.8e-48 164.9 0.1 2.3e-48 164.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KIK32653.1 - 1.1e-06 29.2 0.0 2.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK32653.1 - 3.2e-05 24.5 0.0 6.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KIK32653.1 - 0.00012 21.5 0.0 0.00058 19.2 0.0 1.9 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KIK32653.1 - 0.00015 21.7 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIK32653.1 - 0.00018 21.3 0.0 0.00045 20.0 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KIK32653.1 - 0.00047 19.7 0.0 0.0012 18.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KIK32653.1 - 0.00082 20.1 0.0 0.0016 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KIK32653.1 - 0.005 16.2 0.0 0.0077 15.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_28 PF02636.17 KIK32653.1 - 0.016 14.8 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Met_10 PF02475.16 KIK32653.1 - 0.021 14.6 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein NodS PF05401.11 KIK32653.1 - 0.056 13.1 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_31 PF13847.6 KIK32653.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KIK32653.1 - 0.074 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Glyco_hydro_38N PF01074.22 KIK32655.1 - 2.3e-41 142.1 0.5 4e-41 141.3 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Integrase_H2C2 PF17921.1 KIK32656.1 - 0.068 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Integrase zinc binding domain RVT_1 PF00078.27 KIK32658.1 - 0.0097 15.4 0.0 0.0097 15.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Kre28 PF17097.5 KIK32659.1 - 0.09 11.7 0.1 2 7.3 0.3 2.2 2 0 0 2 2 2 0 Spindle pole body component TFIIA PF03153.13 KIK32659.1 - 1.4 8.8 21.7 0.16 12.0 17.3 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Rdx PF10262.9 KIK32660.1 - 0.021 15.0 0.6 0.063 13.5 0.4 1.8 2 0 0 2 2 2 0 Rdx family Retrotran_gag_2 PF14223.6 KIK32660.1 - 0.13 11.9 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Ldh_1_N PF00056.23 KIK32662.1 - 3.6e-06 27.1 0.0 7.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain RIX1 PF08167.12 KIK32662.1 - 0.037 13.8 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis WD40 PF00400.32 KIK32663.1 - 1.4e-07 32.0 0.0 0.0044 17.8 0.0 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32664.1 - 0.0015 18.8 0.0 0.0025 18.1 0.0 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KIK32664.1 - 0.0054 15.5 0.1 0.0074 15.1 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Peptidase_C23 PF05379.11 KIK32664.1 - 0.1 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Carlavirus endopeptidase Coatomer_WDAD PF04053.14 KIK32664.1 - 0.21 10.6 0.0 0.27 10.2 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region DUF805 PF05656.14 KIK32667.1 - 9.9 6.6 8.8 52 4.3 8.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF805) NACHT PF05729.12 KIK32669.1 - 3e-11 43.5 0.0 5.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK32669.1 - 1.3e-07 32.2 0.1 3.3e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK32669.1 - 0.00079 19.9 0.0 0.0026 18.2 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KIK32669.1 - 0.0042 17.0 0.1 0.0072 16.2 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 KIK32669.1 - 0.016 15.8 0.0 0.035 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KIK32669.1 - 0.03 14.3 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RuvB_N PF05496.12 KIK32669.1 - 0.041 13.6 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KIK32669.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KIK32669.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF4680 PF15730.5 KIK32670.1 - 0.0034 17.7 0.7 0.009 16.4 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4680) Pterin_bind PF00809.22 KIK32670.1 - 0.063 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Pterin binding enzyme Sec5 PF15469.6 KIK32670.1 - 0.09 12.6 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Exocyst complex component Sec5 GMC_oxred_N PF00732.19 KIK32674.1 - 7.6e-58 196.2 0.0 2.3e-29 102.7 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK32674.1 - 0.00012 22.6 0.0 0.00023 21.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK32674.1 - 0.01 14.9 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein pKID PF02173.17 KIK32674.1 - 0.16 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 pKID domain GMC_oxred_C PF05199.13 KIK32675.1 - 2.3e-14 54.1 0.1 2.6e-14 54.0 0.1 1.0 1 0 0 1 1 1 1 GMC oxidoreductase RTC4 PF14474.6 KIK32675.1 - 0.038 14.2 0.0 0.039 14.1 0.0 1.1 1 0 0 1 1 1 0 RTC4-like domain TolA_bind_tri PF16331.5 KIK32676.1 - 0.06 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation Transposase_21 PF02992.14 KIK32677.1 - 7.2e-10 38.5 0.0 8.9e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.12 KIK32677.1 - 0.0011 18.4 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) Plavaka PF18759.1 KIK32677.1 - 0.0077 15.5 0.5 0.01 15.1 0.5 1.2 1 0 0 1 1 1 1 Plavaka transposase DUF4072 PF13284.6 KIK32678.1 - 0.23 11.9 0.4 12 6.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) DDE_3 PF13358.6 KIK32680.1 - 2.3e-05 24.2 0.0 2.6e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plavaka PF18759.1 KIK32683.1 - 4.4e-14 52.4 1.9 7.3e-14 51.7 1.9 1.3 1 0 0 1 1 1 1 Plavaka transposase zf-RVT PF13966.6 KIK32684.1 - 5.2e-05 23.9 0.8 6.9e-05 23.5 0.8 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase WD40 PF00400.32 KIK32686.1 - 6.8e-05 23.6 0.2 0.12 13.2 0.1 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat AAA_5 PF07728.14 KIK32687.1 - 1.3e-09 38.2 0.0 2.1e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Pkinase PF00069.25 KIK32691.1 - 6.7e-08 32.2 0.0 8.9e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Syntaxin-5_N PF11416.8 KIK32691.1 - 0.17 11.2 0.0 0.34 10.2 0.0 1.6 1 0 0 1 1 1 0 Syntaxin-5 N-terminal, Sly1p-binding domain Mt_ATP-synt_B PF05405.14 KIK32692.1 - 0.12 12.0 0.3 0.58 9.8 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) p450 PF00067.22 KIK32697.1 - 4.2e-61 207.1 0.0 1.6e-56 192.0 0.0 2.2 2 1 0 2 2 2 2 Cytochrome P450 Pkinase PF00069.25 KIK32703.1 - 5e-11 42.5 0.1 5.8e-11 42.3 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK32703.1 - 1.2e-05 24.8 0.1 1.3e-05 24.6 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KIK32703.1 - 0.0042 16.7 0.0 0.0051 16.4 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.11 KIK32703.1 - 0.053 12.5 0.2 0.06 12.3 0.2 1.0 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Helicase_C PF00271.31 KIK32704.1 - 3.3e-13 49.9 0.0 1e-12 48.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KIK32704.1 - 2.5e-06 26.9 0.0 4.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SNF2_N PF00176.23 KIK32704.1 - 0.069 11.9 0.1 0.15 10.7 0.0 1.6 2 0 0 2 2 2 0 SNF2 family N-terminal domain CytochromB561_N PF09786.9 KIK32704.1 - 0.17 10.9 0.0 0.25 10.3 0.0 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal SNF2_N PF00176.23 KIK32705.1 - 3.2e-11 42.6 0.0 6.1e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4886 PF16227.5 KIK32705.1 - 0.045 12.9 0.1 5.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4886) WD40 PF00400.32 KIK32707.1 - 4.2e-25 87.5 21.6 5.1e-08 33.5 0.8 5.5 4 1 1 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32707.1 - 2.7e-15 56.4 0.2 0.00018 21.7 0.1 4.3 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK32707.1 - 3.1e-09 36.2 0.0 0.04 12.9 0.0 4.0 2 1 2 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK32707.1 - 0.0028 17.6 0.0 0.14 12.0 0.0 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KIK32707.1 - 0.0037 15.9 0.0 0.0054 15.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nbas_N PF15492.6 KIK32707.1 - 0.0058 16.0 0.1 0.95 8.7 0.0 2.3 1 1 1 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK32707.1 - 0.0068 15.1 0.0 0.01 14.5 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 PD40 PF07676.12 KIK32707.1 - 0.027 14.4 5.1 13 5.9 0.0 5.3 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK32707.1 - 0.06 12.7 0.0 0.22 10.8 0.0 1.9 2 1 0 2 2 2 0 WD40-like domain Nucleoporin_N PF08801.11 KIK32707.1 - 0.088 11.5 0.2 0.78 8.4 0.0 2.0 1 1 1 2 2 2 0 Nup133 N terminal like DUF737 PF05300.11 KIK32712.1 - 0.00097 19.6 5.3 0.0028 18.1 5.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF737) DDE_Tnp_4 PF13359.6 KIK32713.1 - 6.8e-28 97.3 0.0 2e-27 95.8 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KIK32713.1 - 9.7e-07 28.6 0.3 3.8e-06 26.7 0.3 1.9 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 KIK32713.1 - 1.3e-05 24.9 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein tRNA-synt_1_2 PF13603.6 KIK32714.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Plavaka PF18759.1 KIK32716.1 - 7.1e-30 104.3 0.0 1e-29 103.8 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase DUF4599 PF15371.6 KIK32716.1 - 0.061 13.9 0.4 0.41 11.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) Plavaka PF18759.1 KIK32718.1 - 8.1e-117 390.1 0.0 1.1e-116 389.6 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Hit1_C PF18268.1 KIK32718.1 - 0.12 12.6 0.2 12 6.1 0.0 2.4 2 0 0 2 2 2 0 Hit1 C-terminal tRNA-synt_1g PF09334.11 KIK32721.1 - 2.3e-87 293.3 0.0 1.9e-44 152.0 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KIK32721.1 - 5e-23 81.2 1.5 4.6e-12 45.0 0.1 3.8 1 1 3 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KIK32721.1 - 1.5e-07 31.1 0.0 0.0048 16.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KIK32721.1 - 0.018 14.0 0.0 0.063 12.2 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (K) Anticodon_1 PF08264.13 KIK32721.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Cation_efflux PF01545.21 KIK32722.1 - 2.2e-46 158.1 17.9 4.1e-46 157.2 17.9 1.4 1 1 0 1 1 1 1 Cation efflux family WD40 PF00400.32 KIK32723.1 - 0.00012 22.7 0.5 0.0011 19.8 0.2 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat CHAT PF12770.7 KIK32724.1 - 0.015 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 CHAT domain Transp_cyt_pur PF02133.15 KIK32726.1 - 4.3e-29 101.6 1.7 5.1e-29 101.3 1.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Dimer_Tnp_hAT PF05699.14 KIK32731.1 - 1.3e-08 34.5 0.1 1.6e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Doppel PF11466.8 KIK32731.1 - 0.13 11.9 1.4 0.22 11.2 0.1 2.0 1 1 1 2 2 2 0 Prion-like protein Doppel IL11 PF07400.11 KIK32734.1 - 0.071 12.8 0.1 2.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Interleukin 11 Arnt_C PF18583.1 KIK32734.1 - 0.075 12.6 0.6 0.16 11.6 0.1 1.7 2 0 0 2 2 2 0 Aminoarabinose transferase C-terminal domain Ntox50 PF15542.6 KIK32734.1 - 0.51 11.2 4.0 1.1 10.1 2.4 2.4 2 0 0 2 2 2 0 Bacterial toxin 50 Syntaxin-6_N PF09177.11 KIK32734.1 - 1.4 9.5 10.6 10 6.7 0.4 3.6 3 1 0 3 3 3 0 Syntaxin 6, N-terminal KDZ PF18758.1 KIK32738.1 - 2e-62 210.7 2.3 2.2e-62 210.6 2.3 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase TPR_1 PF00515.28 KIK32739.1 - 0.049 13.5 0.1 3.1 7.8 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DDE_1 PF03184.19 KIK32743.1 - 1.9e-05 24.4 0.0 3.4e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease Copper-fist PF00649.18 KIK32744.1 - 0.042 13.4 1.5 0.042 13.4 1.5 1.9 2 0 0 2 2 2 0 Copper fist DNA binding domain zf-CCHC_4 PF14392.6 KIK32744.1 - 3.3 7.5 9.8 0.37 10.6 1.9 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 KIK32744.1 - 6 7.1 6.8 2.6 8.3 3.3 2.1 2 0 0 2 2 2 0 Zinc knuckle Phage_int_SAM_1 PF02899.17 KIK32745.1 - 0.14 12.5 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Phage_integrase PF00589.22 KIK32746.1 - 0.003 17.4 0.0 0.0041 16.9 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DUF1481 PF07356.12 KIK32747.1 - 0.035 13.9 0.5 0.049 13.4 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1481) Mac_assoc PF16628.5 KIK32747.1 - 0.092 13.0 1.8 0.23 11.7 1.1 1.6 1 1 1 2 2 2 0 Unstructured region on maltose acetyltransferase Plavaka PF18759.1 KIK32748.1 - 3.5e-112 374.8 0.0 3.6e-110 368.2 0.0 2.1 1 1 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK32749.1 - 7.9e-09 35.2 0.1 1.3e-08 34.4 0.0 1.4 2 0 0 2 2 2 1 Plavaka transposase DUF366 PF04017.12 KIK32750.1 - 0.052 13.0 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF366) Sortilin-Vps10 PF15902.5 KIK32751.1 - 3.7e-09 35.9 0.1 4.6e-09 35.6 0.1 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Pentapeptide_4 PF13599.6 KIK32753.1 - 0.16 12.1 0.0 0.92 9.7 0.0 1.7 1 1 1 2 2 2 0 Pentapeptide repeats (9 copies) p450 PF00067.22 KIK32755.1 - 2.8e-62 211.0 0.0 3.7e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pox_G5 PF04599.12 KIK32755.1 - 0.16 11.0 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus G5 protein Tam41_Mmp37 PF09139.11 KIK32756.1 - 1.2e-113 379.8 0.0 1.4e-113 379.6 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial DnaJ_CXXCXGXG PF00684.19 KIK32758.1 - 0.0043 17.4 3.8 0.59 10.5 0.2 2.5 2 0 0 2 2 2 2 DnaJ central domain Anti-TRAP PF15777.5 KIK32758.1 - 1.2 9.2 5.9 3.8 7.5 1.0 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Lyase_1 PF00206.20 KIK32759.1 - 2.2e-117 391.9 0.0 3.1e-117 391.4 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KIK32759.1 - 2.3e-19 69.5 0.1 5.1e-19 68.4 0.1 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus B3_4 PF03483.17 KIK32759.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 B3/4 domain RNA_pol_Rpc34 PF05158.12 KIK32760.1 - 0.19 11.0 0.0 0.25 10.7 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit Cactin_mid PF10312.9 KIK32761.1 - 2.1e-62 210.4 2.3 2.1e-62 210.4 2.3 3.2 5 0 0 5 5 5 1 Conserved mid region of cactin CactinC_cactus PF09732.9 KIK32761.1 - 9.1e-60 200.1 5.7 2.1e-59 198.9 5.7 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein GST_N_2 PF13409.6 KIK32762.1 - 1.4e-06 28.5 0.1 4.5e-06 26.9 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIK32762.1 - 1.7e-05 25.1 0.1 6.4e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain BTB PF00651.31 KIK32763.1 - 4.5e-10 39.8 0.1 1.2e-09 38.4 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KIK32764.1 - 1e-06 29.0 0.0 2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain ERCC4 PF02732.15 KIK32765.1 - 6.3e-07 29.7 0.0 1e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain WD40 PF00400.32 KIK32766.1 - 7.9e-21 74.0 5.4 1.8e-09 38.0 0.4 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32766.1 - 2.5e-08 34.1 0.0 0.0043 17.3 0.0 2.9 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK32766.1 - 2.3e-05 24.2 0.6 0.44 10.6 0.1 3.1 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK32766.1 - 6.7e-05 22.0 0.0 0.14 11.1 0.0 2.4 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 KIK32766.1 - 0.0028 17.5 0.2 0.019 14.7 0.1 1.9 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 KIK32766.1 - 0.0074 15.0 0.0 0.46 9.1 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ret2_MD PF18528.1 KIK32766.1 - 0.0094 16.3 0.0 4.6 7.7 0.0 2.2 1 1 1 2 2 2 2 RNA editing 3' terminal uridylyl transferase 2 middle domain WD40_like PF17005.5 KIK32766.1 - 0.03 13.7 0.0 6 6.1 0.0 2.6 1 1 2 3 3 3 0 WD40-like domain Nbas_N PF15492.6 KIK32766.1 - 0.031 13.6 0.0 4 6.7 0.0 2.0 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal dsrm PF00035.26 KIK32766.1 - 0.21 12.3 0.0 19 6.0 0.0 2.7 3 0 0 3 3 3 0 Double-stranded RNA binding motif Proteasome_A_N PF10584.9 KIK32766.1 - 0.33 10.7 3.4 55 3.6 0.1 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Pkinase_fungal PF17667.1 KIK32768.1 - 3.3e-35 121.6 0.0 2.8e-23 82.4 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIK32768.1 - 0.0049 16.3 0.0 0.017 14.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Abhydrolase_3 PF07859.13 KIK32770.1 - 8.5e-59 198.9 0.0 1e-58 198.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIK32770.1 - 1.1e-06 27.8 0.0 3.5e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KIK32770.1 - 6.4e-06 25.3 0.0 7.6e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KIK32770.1 - 0.0071 15.8 0.0 0.084 12.3 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF2974 PF11187.8 KIK32770.1 - 0.065 12.8 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) GATA PF00320.27 KIK32773.1 - 1.6e-09 37.2 6.8 9.6e-09 34.7 3.3 2.1 2 0 0 2 2 2 2 GATA zinc finger DEAD PF00270.29 KIK32775.1 - 4e-09 36.5 0.0 7.4e-07 29.1 0.1 2.2 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK32775.1 - 1.6e-07 31.7 0.0 3.8e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T4SS-DNA_transf PF02534.14 KIK32775.1 - 0.0047 15.8 0.0 0.0071 15.2 0.0 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer KH_dom-like PF14714.6 KIK32775.1 - 0.069 13.5 0.1 0.22 11.9 0.0 1.8 2 0 0 2 2 2 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal ResIII PF04851.15 KIK32775.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit B2-adapt-app_C PF09066.10 KIK32775.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain Tet_JBP PF12851.7 KIK32776.1 - 0.0016 17.8 0.1 0.014 14.7 0.0 2.2 2 1 1 3 3 3 1 Oxygenase domain of the 2OGFeDO superfamily Dynactin_p22 PF07426.11 KIK32776.1 - 0.042 13.7 0.7 0.97 9.3 0.1 2.7 3 0 0 3 3 3 0 Dynactin subunit p22 TRCF PF03461.15 KIK32776.1 - 0.13 12.7 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 TRCF domain DUF1658 PF07871.11 KIK32777.1 - 0.023 14.6 2.3 0.06 13.3 2.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) Peptidase_M17 PF00883.21 KIK32778.1 - 1.5e-43 149.3 0.0 1.8e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Plavaka PF18759.1 KIK32779.1 - 0.00028 20.2 0.5 0.00043 19.6 0.1 1.4 2 0 0 2 2 2 1 Plavaka transposase KDZ PF18758.1 KIK32780.1 - 5.6e-58 196.2 1.6 8.3e-58 195.6 1.6 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF4459 PF14673.6 KIK32781.1 - 0.074 13.0 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4459) Macoilin PF09726.9 KIK32781.1 - 0.55 8.7 8.3 0.78 8.2 8.3 1.1 1 0 0 1 1 1 0 Macoilin family BRO1 PF03097.18 KIK32783.1 - 5.9e-22 78.0 0.0 8.1e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain HTH_32 PF13565.6 KIK32783.1 - 0.19 12.4 0.6 54 4.5 0.5 3.2 3 0 0 3 3 3 0 Homeodomain-like domain Transposase_21 PF02992.14 KIK32784.1 - 2.1e-08 33.7 0.1 5.3e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 KIK32784.1 - 0.019 14.6 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) SPT6_acidic PF14632.6 KIK32786.1 - 2.4 8.8 7.9 4.6 7.9 0.3 2.2 1 1 1 2 2 2 0 Acidic N-terminal SPT6 SWIM PF04434.17 KIK32788.1 - 2.5e-07 30.2 1.0 4.4e-07 29.4 1.0 1.4 1 0 0 1 1 1 1 SWIM zinc finger zf-RVT PF13966.6 KIK32790.1 - 2e-05 25.2 0.1 2.7e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 KIK32792.1 - 1.9e-07 30.8 0.0 2e-07 30.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SH3_10 PF17902.1 KIK32793.1 - 0.22 11.6 1.0 1.9 8.6 1.0 2.0 1 1 0 1 1 1 0 SH3 domain SPOC PF07744.13 KIK32799.1 - 4.4e-07 29.9 0.0 9e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 SPOC domain Sec1 PF00995.23 KIK32800.1 - 0.049 12.9 0.0 0.053 12.7 0.0 1.1 1 0 0 1 1 1 0 Sec1 family Serglycin PF04360.12 KIK32804.1 - 0.098 12.6 5.0 0.12 12.3 5.0 1.1 1 0 0 1 1 1 0 Serglycin DUF4799 PF16056.5 KIK32804.1 - 0.13 11.3 1.6 0.13 11.4 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4799) CxC6 PF18721.1 KIK32806.1 - 6e-26 90.5 6.9 6e-26 90.5 6.9 3.1 3 0 0 3 3 3 1 CxC6 like cysteine cluster associated with KDZ transposases CxC5 PF18718.1 KIK32806.1 - 5.6e-19 68.3 5.6 5.6e-19 68.3 5.6 3.7 3 1 0 3 3 3 1 CxC5 like cysteine cluster associated with KDZ transposases SAT PF16073.5 KIK32806.1 - 0.014 15.2 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis SLD3 PF08639.10 KIK32811.1 - 1.5e-13 50.4 4.7 1.5e-13 50.4 4.7 3.0 1 1 1 2 2 2 1 DNA replication regulator SLD3 DDE_3 PF13358.6 KIK32812.1 - 0.0018 18.1 0.2 0.0051 16.6 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Pkinase_fungal PF17667.1 KIK32813.1 - 6.9e-10 38.3 0.0 7e-10 38.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase DUF4363 PF14276.6 KIK32814.1 - 0.94 9.6 8.2 2.4 8.3 0.6 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) Pkinase PF00069.25 KIK32815.1 - 4.9e-11 42.5 0.0 5.8e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK32815.1 - 6e-07 29.6 0.0 6.6e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KIK32815.1 - 2.4e-06 27.1 0.0 2.6e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KIK32815.1 - 0.0036 16.4 0.1 0.005 15.9 0.1 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 KIK32815.1 - 0.0081 15.0 0.0 0.0092 14.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KIK32815.1 - 0.0087 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KIK32815.1 - 0.031 13.9 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KIK32815.1 - 0.052 12.9 0.0 0.064 12.6 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1256 PF06866.11 KIK32815.1 - 0.14 11.5 0.0 0.67 9.4 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1256) Mcl1_mid PF12341.8 KIK32817.1 - 3.8e-85 285.8 0.0 1.1e-84 284.3 0.0 1.8 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KIK32817.1 - 1.4e-11 44.7 13.8 0.0075 17.1 0.0 7.2 8 1 1 9 9 9 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32817.1 - 1e-07 32.2 0.9 0.17 12.2 0.0 4.8 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KIK32817.1 - 0.012 15.2 1.6 0.039 13.5 0.5 2.4 2 1 0 2 2 2 0 PQQ-like domain Ge1_WD40 PF16529.5 KIK32817.1 - 0.026 13.5 0.1 0.63 8.9 0.0 2.4 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Robl_LC7 PF03259.17 KIK32817.1 - 0.17 11.7 0.3 25 4.7 0.1 2.7 2 0 0 2 2 2 0 Roadblock/LC7 domain Dimer_Tnp_hAT PF05699.14 KIK32819.1 - 8.5e-05 22.3 0.1 0.0001 22.0 0.1 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region EF-hand_4 PF12763.7 KIK32819.1 - 0.15 12.1 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Helicase_C PF00271.31 KIK32820.1 - 0.093 13.1 0.0 0.1 13.0 0.0 1.1 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Plavaka PF18759.1 KIK32825.1 - 1.9e-117 392.1 0.0 2.8e-117 391.6 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase SAGA-Tad1 PF12767.7 KIK32826.1 - 0.013 15.2 7.0 0.28 10.9 7.0 2.1 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit KDZ PF18758.1 KIK32830.1 - 6e-07 29.3 0.0 6.5e-07 29.2 0.0 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase ATPgrasp_N PF18130.1 KIK32831.1 - 0.027 15.0 0.0 0.044 14.4 0.0 1.3 1 1 0 1 1 1 0 ATP-grasp N-terminal domain DUF2865 PF11064.8 KIK32832.1 - 0.31 11.5 2.7 0.32 11.4 0.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2865) AMP-binding_C PF13193.6 KIK32834.1 - 3.2e-07 31.2 0.0 4.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PNTB PF02233.16 KIK32836.1 - 2.6e-26 92.6 5.6 2.6e-26 92.6 5.6 1.4 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit PNTB_4TM PF12769.7 KIK32836.1 - 1.7e-16 60.5 1.9 1.7e-16 60.5 1.9 3.2 2 1 1 3 3 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch Helitron_like_N PF14214.6 KIK32837.1 - 9.1e-23 81.5 0.5 1.1e-22 81.2 0.5 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Cdc13_OB4_dimer PF18233.1 KIK32838.1 - 0.023 14.8 0.4 0.52 10.5 0.0 2.2 2 0 0 2 2 2 0 Cdc13 OB4 dimerization domain SeleniumBinding PF11524.8 KIK32838.1 - 0.19 12.2 0.9 3.8 8.0 0.1 2.4 2 0 0 2 2 2 0 Selenium binding protein p450 PF00067.22 KIK32839.1 - 4.5e-40 137.8 0.0 5.5e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Integrase_H2C2 PF17921.1 KIK32841.1 - 0.094 12.8 2.2 0.44 10.7 0.3 2.1 2 0 0 2 2 2 0 Integrase zinc binding domain DUF5555 PF17710.1 KIK32841.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5555) RRM_occluded PF16842.5 KIK32842.1 - 0.051 13.4 0.0 0.068 13.0 0.0 1.1 1 0 0 1 1 1 0 Occluded RNA-recognition motif FlgM PF04316.13 KIK32843.1 - 0.017 15.4 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM Asp_protease_2 PF13650.6 KIK32844.1 - 2.6e-05 24.8 0.0 3.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK32844.1 - 3.6e-05 24.2 0.0 4.5e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 KIK32844.1 - 0.0015 18.8 0.0 0.002 18.4 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 KIK32844.1 - 0.084 12.4 0.0 0.097 12.2 0.0 1.1 1 0 0 1 1 1 0 Ty3 transposon peptidase Mu-transpos_C PF09299.11 KIK32845.1 - 0.071 13.1 0.0 0.57 10.2 0.0 2.1 2 0 0 2 2 2 0 Mu transposase, C-terminal Transposase_21 PF02992.14 KIK32846.1 - 1.8e-05 24.1 0.0 3.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 KIK32846.1 - 0.027 14.1 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) DUF1932 PF09130.11 KIK32847.1 - 0.0024 17.8 0.4 0.0038 17.1 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) Integrase_H2C2 PF17921.1 KIK32848.1 - 0.06 13.5 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain Phage_capsid PF05065.13 KIK32851.1 - 0.02 14.2 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 Phage capsid family AAA PF00004.29 KIK32854.1 - 0.00049 20.5 0.0 0.00083 19.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIK32854.1 - 0.053 13.5 0.0 0.083 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KIK32854.1 - 0.066 13.2 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 KIK32854.1 - 0.067 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 KIK32854.1 - 0.21 11.7 0.0 0.83 9.8 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain G2F PF07474.12 KIK32855.1 - 0.029 14.1 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 G2F domain Trehalose_PPase PF02358.16 KIK32855.1 - 0.11 11.6 0.1 0.15 11.2 0.1 1.1 1 0 0 1 1 1 0 Trehalose-phosphatase HSP20 PF00011.21 KIK32857.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.3 1 1 0 1 1 1 0 Hsp20/alpha crystallin family Pkinase_fungal PF17667.1 KIK32859.1 - 2.5e-41 141.8 0.0 4e-22 78.6 0.0 3.0 2 1 1 3 3 3 2 Fungal protein kinase Pkinase PF00069.25 KIK32859.1 - 0.0012 18.3 0.0 0.0026 17.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK32860.1 - 3.2e-18 65.7 0.0 4e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK32860.1 - 0.00024 20.6 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Eapp_C PF10238.9 KIK32864.1 - 3.1 7.9 8.3 3.1 7.8 8.3 1.0 1 0 0 1 1 1 0 E2F-associated phosphoprotein WD40 PF00400.32 KIK32865.1 - 6.4e-31 105.9 16.5 3.8e-09 37.0 0.3 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32865.1 - 2.9e-11 43.5 0.2 0.017 15.4 0.0 4.7 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WW PF00397.26 KIK32865.1 - 1.3e-07 31.6 6.0 2.6e-06 27.4 0.4 3.1 2 0 0 2 2 2 2 WW domain Ge1_WD40 PF16529.5 KIK32865.1 - 0.012 14.6 0.0 1.6 7.6 0.0 3.3 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK32865.1 - 0.017 13.8 0.0 0.34 9.5 0.0 2.5 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Cys_Met_Meta_PP PF01053.20 KIK32866.1 - 2.1e-09 36.4 0.1 2.2e-09 36.3 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme CxC6 PF18721.1 KIK32870.1 - 1.8e-23 82.6 10.3 1.8e-23 82.6 10.3 2.2 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases DR2241 PF18069.1 KIK32870.1 - 0.04 13.8 0.5 0.082 12.8 0.5 1.5 1 0 0 1 1 1 0 DR2241 stabilising domain zf-like PF04071.12 KIK32870.1 - 0.06 13.3 4.5 0.16 11.9 4.5 1.7 1 0 0 1 1 1 0 Cysteine-rich small domain BUD22 PF09073.10 KIK32871.1 - 2.7e-05 23.7 15.2 3.1e-05 23.5 15.2 1.1 1 0 0 1 1 1 1 BUD22 rve PF00665.26 KIK32871.1 - 0.00023 21.4 0.0 0.0004 20.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF1168 PF06658.12 KIK32871.1 - 0.034 14.0 26.6 0.059 13.2 26.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) RNA_pol_Rpc4 PF05132.14 KIK32871.1 - 1.4 9.4 9.2 2.9 8.3 9.2 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Cellulose_synt PF03552.14 KIK32871.1 - 2.7 6.3 5.7 13 4.1 0.0 2.0 2 0 0 2 2 2 0 Cellulose synthase RRN3 PF05327.11 KIK32871.1 - 5.6 5.4 17.9 16 3.9 16.7 1.9 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 RT_RNaseH_2 PF17919.1 KIK32872.1 - 8.2e-12 45.0 0.0 9.2e-12 44.9 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PP2C_2 PF13672.6 KIK32872.1 - 0.0043 16.7 0.0 0.0043 16.7 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C RT_RNaseH PF17917.1 KIK32872.1 - 0.066 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KIK32873.1 - 6.2e-05 22.6 0.0 6.2e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pepsin-I3 PF06394.13 KIK32874.1 - 0.014 15.6 0.2 0.82 9.9 0.1 2.2 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain gag-asp_proteas PF13975.6 KIK32875.1 - 0.0038 17.8 0.0 0.0056 17.2 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Mt_ATP-synt_D PF05873.12 KIK32876.1 - 0.0037 17.1 0.2 0.0084 16.0 0.2 1.6 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF3336 PF11815.8 KIK32876.1 - 0.015 15.0 0.1 0.029 14.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3336) FliD_N PF02465.18 KIK32876.1 - 0.21 12.3 4.7 0.4 11.4 2.5 2.6 3 1 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus zf-CCHC_2 PF13696.6 KIK32876.1 - 0.79 9.6 2.2 1.3 8.9 2.2 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 KIK32876.1 - 3.7 7.8 5.5 6.5 7.0 5.5 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4413 PF14372.6 KIK32878.1 - 7.2e-05 23.1 0.1 8.2e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) Dimer_Tnp_hAT PF05699.14 KIK32879.1 - 1.5e-16 59.9 0.1 2.1e-16 59.5 0.1 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CxC2 PF18803.1 KIK32881.1 - 1.9e-37 127.6 0.1 4.6e-37 126.4 0.1 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK32881.1 - 0.00032 20.8 0.1 0.00088 19.4 0.1 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases TP_methylase PF00590.20 KIK32882.1 - 5.8e-12 46.0 0.3 7e-12 45.7 0.3 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-P11 PF03854.14 KIK32885.1 - 0.67 9.7 4.2 5 6.9 4.2 2.1 1 1 0 1 1 1 0 P-11 zinc finger Helitron_like_N PF14214.6 KIK32886.1 - 1.5e-33 116.6 0.1 1.7e-33 116.4 0.1 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus zf-RVT PF13966.6 KIK32889.1 - 7.7e-05 23.3 0.2 0.0001 23.0 0.2 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase KRAB PF01352.27 KIK32890.1 - 0.045 13.4 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 KRAB box Retrotran_gag_2 PF14223.6 KIK32891.1 - 1.5e-10 40.8 0.0 1.7e-10 40.7 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KIK32892.1 - 0.051 13.4 0.0 0.076 12.8 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type WD40 PF00400.32 KIK32893.1 - 3.7e-09 37.1 0.0 1.8e-05 25.4 0.0 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32893.1 - 0.00046 20.4 0.1 0.065 13.5 0.0 2.7 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK32893.1 - 0.11 12.5 0.0 8.3 6.5 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 KIK32894.1 - 9.8e-25 86.4 10.9 7.3e-09 36.1 3.0 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32894.1 - 4.5e-14 52.5 1.8 4.4e-06 26.9 0.3 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK32894.1 - 2.6e-05 23.1 2.6 0.22 10.1 0.4 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PQQ PF01011.21 KIK32894.1 - 0.00016 21.4 0.0 0.97 9.5 0.0 3.6 3 0 0 3 3 3 1 PQQ enzyme repeat Ge1_WD40 PF16529.5 KIK32894.1 - 0.00023 20.2 0.0 0.073 12.0 0.0 2.6 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK32894.1 - 0.0005 19.5 0.9 0.018 14.4 0.1 2.7 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal SGL PF08450.12 KIK32894.1 - 0.00066 19.3 0.3 0.00083 19.0 0.3 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region eIF2A PF08662.11 KIK32894.1 - 0.0018 18.2 0.2 0.003 17.5 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 KIK32894.1 - 0.011 16.3 5.7 0.6 10.7 2.4 3.2 2 1 1 3 3 3 0 PQQ-like domain WD40_like PF17005.5 KIK32894.1 - 0.017 14.5 0.0 0.075 12.4 0.0 1.8 1 1 1 2 2 2 0 WD40-like domain p450 PF00067.22 KIK32896.1 - 2.6e-45 155.0 0.0 3.1e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3819 PF12842.7 KIK32898.1 - 1.9e-29 102.5 0.3 2.1e-29 102.3 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) WD40 PF00400.32 KIK32899.1 - 4.8e-14 52.5 0.0 0.0006 20.6 0.0 3.0 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32899.1 - 5e-06 26.7 0.0 0.0024 18.1 0.0 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Me-amine-dh_H PF06433.11 KIK32899.1 - 0.00038 19.4 0.0 0.00045 19.2 0.0 1.0 1 0 0 1 1 1 1 Methylamine dehydrogenase heavy chain (MADH) PALB2_WD40 PF16756.5 KIK32899.1 - 0.00048 19.2 0.0 0.036 13.0 0.0 2.0 1 1 1 2 2 2 2 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 KIK32899.1 - 0.0015 18.2 0.1 0.0017 18.0 0.1 1.2 1 0 0 1 1 1 1 PQQ-like domain DUF1513 PF07433.11 KIK32899.1 - 0.0021 17.2 0.1 0.0025 17.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.16 KIK32899.1 - 0.043 12.4 0.1 0.051 12.1 0.1 1.0 1 0 0 1 1 1 0 Cytochrome D1 heme domain CysG_dimeriser PF10414.9 KIK32901.1 - 0.072 12.8 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region Cauli_VI PF01693.16 KIK32902.1 - 1.6e-12 47.5 2.8 2.7e-12 46.8 2.8 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin IDO PF01231.18 KIK32902.1 - 0.063 12.1 0.1 0.089 11.6 0.1 1.1 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase R3H PF01424.22 KIK32907.1 - 2.8e-14 52.8 0.2 4.9e-14 52.0 0.2 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 KIK32907.1 - 0.00016 21.7 39.5 0.00025 21.0 12.9 13.6 15 0 0 15 15 15 6 NF-X1 type zinc finger Retrotrans_gag PF03732.17 KIK32910.1 - 0.08 13.2 0.4 0.82 10.0 0.6 2.2 1 1 0 2 2 2 0 Retrotransposon gag protein Phage_integrase PF00589.22 KIK32911.1 - 0.0084 15.9 0.0 0.019 14.8 0.0 1.7 1 1 0 1 1 1 1 Phage integrase family 30K_MP_C_Ter PF11330.8 KIK32913.1 - 0.25 10.6 0.0 0.34 10.2 0.0 1.1 1 0 0 1 1 1 0 C-Terminal of 30K viral movement proteins WD40 PF00400.32 KIK32915.1 - 1.8e-38 129.9 16.9 1.2e-08 35.5 0.4 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32915.1 - 1.4e-16 60.6 4.2 0.0027 18.0 0.0 6.2 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK32915.1 - 2.5e-08 33.3 0.0 0.0063 15.5 0.0 4.1 2 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK32915.1 - 4.2e-05 23.5 0.3 0.00026 20.9 0.1 2.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KIK32915.1 - 0.00022 20.7 0.5 0.094 12.0 0.1 4.0 2 2 2 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK32915.1 - 0.0012 17.5 0.4 9.1 4.8 0.0 4.1 4 0 0 4 4 4 1 Nucleoporin Nup120/160 PD40 PF07676.12 KIK32915.1 - 0.02 14.8 0.0 22 5.1 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Hira PF07569.11 KIK32915.1 - 0.042 13.6 0.1 4.3 7.0 0.0 3.2 3 1 1 4 4 4 0 TUP1-like enhancer of split PQQ PF01011.21 KIK32915.1 - 0.072 13.0 0.3 76 3.5 0.3 3.6 3 0 0 3 3 3 0 PQQ enzyme repeat Frtz PF11768.8 KIK32915.1 - 0.099 10.9 0.0 2.3 6.4 0.0 2.3 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 KIK32916.1 - 2.3e-42 142.2 12.9 5.1e-06 27.1 0.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32916.1 - 1.3e-21 76.7 2.7 3.5e-07 30.4 0.1 6.2 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK32916.1 - 7.2e-10 39.1 0.1 0.0055 16.6 0.0 3.3 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK32916.1 - 4.6e-08 32.4 0.3 0.021 13.8 0.0 4.3 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK32916.1 - 1.1e-06 28.2 0.0 0.44 9.8 0.0 4.0 3 1 0 4 4 4 2 WD40-like domain Nup160 PF11715.8 KIK32916.1 - 1.8e-05 23.6 6.6 0.75 8.4 0.6 4.7 2 2 3 5 5 5 3 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK32916.1 - 0.0042 16.5 0.2 0.063 12.6 0.0 2.6 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PQQ PF01011.21 KIK32916.1 - 0.0078 16.1 1.7 33 4.7 0.0 5.0 6 1 2 8 8 8 0 PQQ enzyme repeat VID27 PF08553.10 KIK32916.1 - 0.017 14.2 0.1 4.4 6.3 0.0 2.7 2 1 1 3 3 3 0 VID27 C-terminal WD40-like domain RAB3GAP2_N PF14655.6 KIK32916.1 - 0.033 13.5 0.0 0.32 10.2 0.0 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus LigD_N PF13298.6 KIK32916.1 - 0.057 13.7 0.6 22 5.4 0.1 2.8 2 1 0 3 3 3 0 DNA polymerase Ligase (LigD) PD40 PF07676.12 KIK32916.1 - 0.098 12.6 0.0 25 4.9 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF5570 PF17731.1 KIK32916.1 - 0.54 10.3 3.4 1.4 9.0 0.1 3.3 4 1 1 5 5 5 0 Family of unknown function (DUF5570) PsbR PF04725.12 KIK32917.1 - 0.2 12.0 0.0 0.43 11.0 0.0 1.5 1 0 0 1 1 1 0 Photosystem II 10 kDa polypeptide PsbR DUF5102 PF17104.5 KIK32920.1 - 0.0078 16.3 0.2 0.012 15.7 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) FliC PF12445.8 KIK32920.1 - 4 7.8 16.6 2 8.8 6.5 3.2 2 1 1 3 3 3 0 Flagellin protein Glyco_hydro_3 PF00933.21 KIK32921.1 - 1.8e-10 40.7 0.0 2.4e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Ad_cyc_g-alpha PF08509.11 KIK32921.1 - 0.079 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Adenylate cyclase G-alpha binding domain LigT_PEase PF02834.16 KIK32924.1 - 0.0065 16.6 0.0 0.57 10.4 0.0 2.1 2 0 0 2 2 2 2 LigT like Phosphoesterase WD40 PF00400.32 KIK32925.1 - 3.1e-06 27.8 0.2 8.4e-06 26.4 0.1 1.7 2 0 0 2 2 2 1 WD domain, G-beta repeat ORC6 PF05460.13 KIK32926.1 - 0.44 9.8 6.9 0.6 9.3 6.9 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Npa1 PF11707.8 KIK32929.1 - 0.00079 18.9 0.0 0.00079 18.9 0.0 1.0 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal WD40 PF00400.32 KIK32933.1 - 5.4e-27 93.5 21.2 7.6e-08 32.9 3.7 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32933.1 - 2.3e-19 69.5 0.7 0.00083 19.6 0.1 5.8 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK32933.1 - 2.6e-08 33.2 0.0 0.0032 16.5 0.0 3.2 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KIK32933.1 - 1.3e-05 23.9 0.0 0.00017 20.2 0.0 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain eIF2A PF08662.11 KIK32933.1 - 3e-05 24.0 0.4 0.0075 16.2 0.1 3.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KIK32933.1 - 3.9e-05 23.1 1.3 0.021 14.2 0.1 3.7 2 2 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KIK32933.1 - 0.00033 20.5 1.7 17 5.5 0.2 5.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK32933.1 - 0.0026 16.5 3.2 0.032 12.9 0.1 3.1 3 1 0 3 3 3 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK32933.1 - 0.0063 15.9 0.0 0.038 13.3 0.0 2.1 3 0 0 3 3 3 1 WD40-like domain CRT10 PF08728.10 KIK32933.1 - 0.01 14.1 0.0 0.019 13.2 0.0 1.4 2 0 0 2 2 2 1 CRT10 PQQ PF01011.21 KIK32933.1 - 0.029 14.3 2.2 44 4.3 0.0 4.7 4 0 0 4 4 4 0 PQQ enzyme repeat PQQ_3 PF13570.6 KIK32933.1 - 0.046 14.2 3.9 18 6.0 0.0 3.8 3 1 0 3 3 3 0 PQQ-like domain gag-asp_proteas PF13975.6 KIK32935.1 - 0.00049 20.6 0.8 0.0023 18.4 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIK32935.1 - 0.0011 19.5 0.2 0.0052 17.4 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 KIK32935.1 - 0.035 13.9 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease DRY_EERY PF09750.9 KIK32935.1 - 8.3 6.7 11.3 0.56 10.5 3.4 2.3 2 0 0 2 2 2 0 Alternative splicing regulator Asp_protease_2 PF13650.6 KIK32936.1 - 1.9e-05 25.2 0.0 2.2e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK32936.1 - 6.8e-05 23.3 0.0 7.9e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KIK32936.1 - 0.003 17.3 0.0 0.0032 17.3 0.0 1.0 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KIK32936.1 - 0.023 15.0 0.0 0.031 14.6 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease CRISPR_Cas9_WED PF18061.1 KIK32940.1 - 0.11 12.5 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 CRISPR-Cas9 WED domain ZZ PF00569.17 KIK32941.1 - 0.31 10.9 23.3 0.077 12.8 11.5 2.5 2 0 0 2 2 2 0 Zinc finger, ZZ type LXG PF04740.12 KIK32941.1 - 0.33 10.6 3.3 0.53 10.0 1.3 2.4 2 0 0 2 2 2 0 LXG domain of WXG superfamily Abhydrolase_6 PF12697.7 KIK32942.1 - 3.3e-05 24.6 0.5 4.4e-05 24.2 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family ddrB-ParB PF18763.1 KIK32944.1 - 0.066 13.3 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 ddrB-like ParB superfamily domain SAA PF00277.18 KIK32944.1 - 0.073 13.6 0.0 12 6.4 0.0 2.2 2 0 0 2 2 2 0 Serum amyloid A protein SBF PF01758.16 KIK32945.1 - 0.025 14.3 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Sodium Bile acid symporter family Uricase PF01014.18 KIK32947.1 - 6.8e-10 39.3 0.0 9.9e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Uricase PLDc_N PF13396.6 KIK32949.1 - 0.069 13.1 2.1 0.11 12.5 2.1 1.3 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal GST_N_3 PF13417.6 KIK32951.1 - 4e-09 36.8 0.1 1.5e-08 34.9 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK32951.1 - 9e-07 29.1 0.0 2.9e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK32951.1 - 7.2e-05 22.9 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK32951.1 - 0.00063 19.9 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK32951.1 - 0.024 14.7 0.1 0.046 13.7 0.1 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIK32953.1 - 8e-11 42.2 0.1 3.5e-10 40.2 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK32953.1 - 4.9e-08 33.2 0.0 1.2e-07 31.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK32953.1 - 0.00024 21.3 0.0 0.00044 20.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK32953.1 - 0.00091 19.4 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK32953.1 - 0.0056 16.7 0.1 0.014 15.4 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Plavaka PF18759.1 KIK32956.1 - 2.1e-35 122.5 0.0 3.1e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase SDA1 PF05285.12 KIK32956.1 - 0.0057 16.1 7.1 0.0086 15.5 7.1 1.2 1 0 0 1 1 1 1 SDA1 ATG11 PF10377.9 KIK32959.1 - 0.012 15.6 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 11 LPD39 PF18858.1 KIK32959.1 - 0.057 13.5 0.0 0.072 13.2 0.0 1.1 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 Vinculin PF01044.19 KIK32960.1 - 0.15 10.3 0.1 0.16 10.2 0.1 1.0 1 0 0 1 1 1 0 Vinculin family FlgM PF04316.13 KIK32961.1 - 0.07 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM gag-asp_proteas PF13975.6 KIK32962.1 - 1.3e-05 25.6 0.0 1.4e-05 25.5 0.0 1.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIK32962.1 - 8e-05 23.2 0.0 9.1e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KIK32962.1 - 0.0019 18.5 0.0 0.0023 18.2 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 KIK32962.1 - 0.04 13.5 0.0 0.043 13.4 0.0 1.0 1 0 0 1 1 1 0 Ty3 transposon peptidase Plavaka PF18759.1 KIK32966.1 - 2.1e-20 73.2 0.1 4e-20 72.3 0.1 1.4 1 0 0 1 1 1 1 Plavaka transposase HypD PF01924.16 KIK32966.1 - 0.026 13.6 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase formation hypA family zf-C2H2 PF00096.26 KIK32968.1 - 0.013 15.9 1.0 0.027 14.9 1.0 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type GED PF02212.18 KIK32968.1 - 0.093 12.9 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Dynamin GTPase effector domain RHH_5 PF07878.11 KIK32969.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 Vps16_C PF04840.12 KIK32973.1 - 1.1e-78 264.5 0.1 1.6e-78 264.0 0.1 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 KIK32973.1 - 4.1e-70 236.6 0.0 6.1e-70 236.0 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Sigma70_ner PF04546.13 KIK32974.1 - 0.032 14.1 0.0 0.035 14.0 0.0 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region WD40 PF00400.32 KIK32977.1 - 1.2e-20 73.4 3.1 4.9e-07 30.3 0.1 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32977.1 - 0.00012 22.4 0.1 0.54 10.6 0.0 3.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK32977.1 - 0.0035 16.1 0.2 0.032 12.9 0.0 1.9 2 0 0 2 2 2 1 Nucleoporin Nup120/160 WD40 PF00400.32 KIK32980.1 - 5e-30 103.1 4.2 6.7e-08 33.1 1.2 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32980.1 - 8e-08 32.5 0.1 0.75 10.1 0.0 4.4 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK32980.1 - 0.001 17.8 0.0 0.75 8.4 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PD40 PF07676.12 KIK32980.1 - 0.014 15.3 0.0 28 4.8 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK32980.1 - 0.044 13.1 0.0 0.47 9.7 0.0 2.6 2 1 0 2 2 2 0 WD40-like domain DUF5542 PF17696.1 KIK32981.1 - 0.052 13.7 0.0 0.063 13.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5542) DUF2569 PF10754.9 KIK32982.1 - 0.11 13.0 4.5 0.14 12.6 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) SNF2_N PF00176.23 KIK32984.1 - 1.9e-39 135.4 5.3 2.2e-30 105.6 1.1 2.5 2 1 1 3 3 3 2 SNF2 family N-terminal domain PIF1 PF05970.14 KIK32985.1 - 8.4e-09 35.0 0.0 9.3e-09 34.9 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIK32985.1 - 0.0013 18.5 0.0 0.0013 18.5 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIK32986.1 - 1.7e-07 31.1 0.2 2.9e-07 30.4 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK32986.1 - 1.2e-05 25.6 0.3 1.6e-05 25.3 0.3 1.2 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 KIK32986.1 - 0.00022 20.5 0.0 0.00022 20.5 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.6 KIK32986.1 - 0.00038 20.9 0.0 0.00047 20.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KIK32986.1 - 0.001 18.8 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 KIK32986.1 - 0.002 18.6 0.2 0.003 18.0 0.2 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KIK32986.1 - 0.002 17.9 0.0 0.0022 17.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KIK32986.1 - 0.011 14.9 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KIK32986.1 - 0.011 15.0 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 KIK32986.1 - 0.012 15.8 0.1 0.016 15.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK32986.1 - 0.021 14.4 0.3 0.04 13.4 0.1 1.4 1 1 1 2 2 2 0 P-loop containing dynein motor region Rad17 PF03215.15 KIK32986.1 - 0.033 14.1 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain ResIII PF04851.15 KIK32986.1 - 0.037 14.0 0.0 0.043 13.8 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SMC_N PF02463.19 KIK32986.1 - 0.046 13.1 0.0 0.064 12.7 0.0 1.3 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain NB-ARC PF00931.22 KIK32986.1 - 0.047 12.9 0.0 0.06 12.5 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.17 KIK32986.1 - 0.051 13.3 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Parvo_NS1 PF01057.17 KIK32986.1 - 0.062 12.4 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 KIK32986.1 - 0.064 13.3 0.0 0.075 13.0 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KIK32986.1 - 0.064 12.6 0.1 0.075 12.4 0.1 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KIK32986.1 - 0.065 12.4 0.0 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KIK32986.1 - 0.089 12.5 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 KIK32986.1 - 0.089 12.5 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KIK32986.1 - 0.089 12.8 0.1 0.23 11.5 0.1 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Torsin PF06309.11 KIK32986.1 - 0.11 12.7 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Torsin AAA_PrkA PF08298.11 KIK32986.1 - 0.12 11.3 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain NTPase_1 PF03266.15 KIK32986.1 - 0.13 12.2 0.1 0.18 11.7 0.1 1.2 1 0 0 1 1 1 0 NTPase AAA_21 PF13304.6 KIK32986.1 - 0.19 11.5 0.0 0.33 10.7 0.0 1.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system zf-NF-X1 PF01422.17 KIK32987.1 - 0.069 13.2 3.3 0.17 12.0 3.3 1.7 1 0 0 1 1 1 0 NF-X1 type zinc finger CobA_CobO_BtuR PF02572.15 KIK32987.1 - 0.19 11.9 0.0 0.28 11.4 0.0 1.2 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP HSP70 PF00012.20 KIK32989.1 - 1.5e-40 139.0 0.0 1.6e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein FGGY_C PF02782.16 KIK32989.1 - 0.0008 19.2 0.0 0.00098 18.9 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Chlam_OMP3 PF03503.13 KIK32989.1 - 0.045 14.1 0.1 0.075 13.4 0.1 1.3 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 3 DUF1464 PF07318.12 KIK32989.1 - 0.1 11.7 0.0 0.12 11.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) XPG_I PF00867.18 KIK32990.1 - 1.5e-19 70.1 0.0 2.5e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KIK32990.1 - 0.0024 18.3 0.0 0.0046 17.4 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KIK32990.1 - 0.093 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 XPG domain containing WD40 PF00400.32 KIK32993.1 - 7e-21 74.2 6.2 3.1e-09 37.3 1.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK32993.1 - 1.6e-05 25.1 0.3 0.84 10.0 0.1 3.5 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK32993.1 - 0.0045 15.7 0.0 0.006 15.3 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 PD40 PF07676.12 KIK32993.1 - 0.0074 16.2 0.0 7 6.7 0.0 3.1 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK32993.1 - 0.018 14.4 0.0 0.3 10.4 0.0 2.3 2 1 1 3 3 3 0 WD40-like domain Plavaka PF18759.1 KIK32995.1 - 1.1e-117 393.0 6.2 1.7e-98 329.8 0.0 2.5 2 1 1 3 3 3 2 Plavaka transposase Amino_oxidase PF01593.24 KIK32996.1 - 0.05 12.9 0.1 0.061 12.6 0.1 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Plavaka PF18759.1 KIK32998.1 - 9.2e-123 409.6 0.0 1.2e-122 409.2 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2 PF00096.26 KIK32998.1 - 0.00013 22.2 0.5 0.00045 20.5 0.5 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-Di19 PF05605.12 KIK32998.1 - 0.012 15.9 0.6 0.026 14.8 0.6 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KIK32998.1 - 0.017 15.9 1.9 0.029 15.2 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger HetR_C PF18460.1 KIK32999.1 - 0.012 15.5 0.0 0.04 13.8 0.0 1.8 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain zf-RVT PF13966.6 KIK33000.1 - 9.2e-05 23.1 0.2 0.00012 22.7 0.2 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase XRN_N PF03159.18 KIK33002.1 - 4.4e-33 114.7 0.1 5.1e-33 114.5 0.1 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Mucin PF01456.17 KIK33004.1 - 0.00039 20.4 7.2 0.00039 20.4 7.2 3.0 3 1 1 4 4 4 1 Mucin-like glycoprotein DUF3729 PF12526.8 KIK33004.1 - 6.4 8.4 18.9 4 9.0 5.8 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3729) LRR19-TM PF15176.6 KIK33006.1 - 0.2 11.7 0.3 0.26 11.3 0.3 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain WD40 PF00400.32 KIK33007.1 - 2.8e-39 132.4 18.5 1.9e-07 31.6 1.0 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33007.1 - 7.5e-17 61.4 6.8 0.0014 18.9 0.0 6.3 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KIK33007.1 - 9.8e-06 25.1 0.2 0.0015 17.9 0.0 3.6 1 1 3 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK33007.1 - 2.4e-05 23.2 2.4 0.082 11.5 0.0 3.9 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK33007.1 - 4.6e-05 22.5 0.0 2.7 6.9 0.0 5.0 1 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK33007.1 - 4.8e-05 23.3 0.3 0.0048 16.8 0.1 2.7 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KIK33007.1 - 0.00062 18.4 0.4 0.003 16.2 0.0 2.2 2 1 0 3 3 3 1 Cytochrome D1 heme domain WD40_like PF17005.5 KIK33007.1 - 0.00075 18.9 0.0 3.6 6.8 0.0 3.5 2 1 2 4 4 4 2 WD40-like domain FAD_binding_3 PF01494.19 KIK33010.1 - 3.5e-45 154.8 0.0 1.7e-27 96.6 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KIK33010.1 - 5.8e-08 32.3 1.3 0.0024 17.2 0.1 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIK33010.1 - 1.2e-05 24.4 0.3 0.0073 15.2 0.0 2.4 3 0 0 3 3 3 2 Tryptophan halogenase HI0933_like PF03486.14 KIK33010.1 - 1.5e-05 24.0 0.1 0.13 11.0 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 KIK33010.1 - 1.6e-05 24.6 0.2 0.0017 18.0 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KIK33010.1 - 3.8e-05 23.1 0.1 0.00027 20.3 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK33010.1 - 4.3e-05 22.7 0.7 0.6 9.1 0.1 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK33010.1 - 0.0026 16.9 0.8 0.0069 15.5 0.3 1.8 1 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KIK33010.1 - 0.0059 16.8 0.1 0.014 15.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 KIK33010.1 - 0.016 14.3 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase FAD_oxidored PF12831.7 KIK33010.1 - 0.024 14.0 0.3 0.057 12.8 0.3 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KIK33010.1 - 0.037 13.3 0.1 0.088 12.0 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KIK33010.1 - 0.056 14.0 0.1 7 7.3 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KIK33010.1 - 0.081 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KIK33010.1 - 0.094 12.7 0.4 0.28 11.2 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Cse1 PF08506.10 KIK33011.1 - 0.011 14.6 0.0 0.012 14.5 0.0 1.0 1 0 0 1 1 1 0 Cse1 F420H2_quin_red PF04075.14 KIK33013.1 - 0.025 14.7 0.0 0.029 14.5 0.0 1.0 1 0 0 1 1 1 0 F420H(2)-dependent quinone reductase CxC6 PF18721.1 KIK33014.1 - 3.6e-20 72.0 5.2 3.6e-20 72.0 5.2 2.0 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases TPR_10 PF13374.6 KIK33017.1 - 1.8e-11 43.5 12.8 0.063 13.2 0.0 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat CHAT PF12770.7 KIK33017.1 - 1.3e-06 28.1 0.0 2.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 KIK33017.1 - 0.00034 20.8 16.3 5.7 7.3 0.1 7.7 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK33017.1 - 0.0012 18.7 5.3 21 5.4 0.1 6.2 6 1 0 6 6 6 1 Tetratricopeptide repeat Zeta_toxin PF06414.12 KIK33017.1 - 0.026 13.8 0.0 0.064 12.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin TPR_2 PF07719.17 KIK33017.1 - 0.26 11.5 4.7 21 5.5 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK33017.1 - 0.75 9.7 3.9 43 4.2 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Vta1_C PF18097.1 KIK33017.1 - 1.5 8.6 7.2 0.62 9.8 0.1 3.8 4 0 0 4 4 4 0 Vta1 C-terminal domain MFS_1 PF07690.16 KIK33021.1 - 1.8e-24 86.3 54.8 1.2e-22 80.4 27.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK33021.1 - 0.28 10.0 19.1 1.2 8.0 19.1 1.8 1 1 0 1 1 1 0 Sugar (and other) transporter BRCT_3 PF18428.1 KIK33022.1 - 0.033 14.2 0.0 0.038 14.1 0.0 1.1 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain WD40 PF00400.32 KIK33023.1 - 4e-34 116.1 17.1 2.3e-07 31.4 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33023.1 - 5.8e-13 49.0 0.2 0.0077 16.5 0.0 4.8 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK33023.1 - 2.6e-05 23.1 0.0 0.2 10.3 0.1 3.7 2 1 3 5 5 5 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK33023.1 - 0.0024 17.3 0.1 2.5 7.4 0.0 2.6 2 1 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.9 KIK33023.1 - 0.0043 16.8 0.1 0.12 12.1 0.1 2.2 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Ge1_WD40 PF16529.5 KIK33023.1 - 0.018 14.0 0.0 3.1 6.7 0.0 3.5 1 1 4 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF202 PF02656.15 KIK33026.1 - 1.5 9.4 6.1 0.45 11.0 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) HAUS-augmin3 PF14932.6 KIK33030.1 - 0.0054 16.4 1.0 0.01 15.5 1.0 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 KIK33030.1 - 0.034 13.0 4.2 0.05 12.5 4.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ZapB PF06005.12 KIK33030.1 - 0.079 13.4 1.1 0.27 11.7 1.1 1.9 1 1 0 1 1 1 0 Cell division protein ZapB NUDE_C PF04880.13 KIK33030.1 - 0.83 10.1 0.0 0.83 10.1 0.0 3.1 3 0 0 3 3 3 0 NUDE protein, C-terminal conserved region Nucleoporin_FG2 PF15967.5 KIK33031.1 - 0.0022 16.6 1.2 0.0035 16.0 1.2 1.3 1 0 0 1 1 1 1 Nucleoporin FG repeated region Allatostatin PF05953.12 KIK33031.1 - 2 9.3 6.4 34 5.5 0.1 4.7 5 0 0 5 5 5 0 Allatostatin MFS_1 PF07690.16 KIK33032.1 - 2e-35 122.3 31.8 2e-35 122.3 31.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK33032.1 - 2.7e-32 112.2 24.9 1.3e-31 110.0 24.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Peptidase_S10 PF00450.22 KIK33033.1 - 2.7e-31 109.4 0.1 1.4e-25 90.5 0.4 2.1 1 1 1 2 2 2 2 Serine carboxypeptidase MMR_HSR1 PF01926.23 KIK33038.1 - 8.1e-06 25.9 0.0 2e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK33038.1 - 2.7e-05 24.1 0.1 0.011 15.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 KIK33038.1 - 0.0016 17.7 0.1 0.23 10.6 0.1 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_16 PF13191.6 KIK33038.1 - 0.005 17.2 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 KIK33038.1 - 0.0072 16.5 0.0 0.16 12.2 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 KIK33038.1 - 0.052 12.7 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Septin PF00735.18 KIK33038.1 - 0.061 12.6 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Septin Recep_L_domain PF01030.24 KIK33038.1 - 0.084 13.0 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Receptor L domain ATP_bind_1 PF03029.17 KIK33038.1 - 0.086 12.6 0.9 6.6 6.4 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 KIK33038.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase_Tyr PF07714.17 KIK33039.1 - 2.3e-43 148.4 0.0 3.1e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK33039.1 - 3.5e-33 115.1 0.0 4.8e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK33039.1 - 5.9e-05 22.0 0.5 9.8e-05 21.3 0.5 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIK33039.1 - 0.00099 18.5 0.1 0.0022 17.4 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIK33039.1 - 0.0094 15.3 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KIK33039.1 - 0.021 14.4 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family ABC1 PF03109.16 KIK33039.1 - 0.042 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 ABC1 family APH PF01636.23 KIK33039.1 - 0.043 13.7 0.1 0.089 12.7 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF805 PF05656.14 KIK33040.1 - 0.23 11.9 7.9 0.32 11.4 6.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF805) Frag1 PF10277.9 KIK33042.1 - 0.0049 16.4 1.2 0.0061 16.1 1.2 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Metal_resist PF13801.6 KIK33046.1 - 0.027 14.7 3.6 0.17 12.1 0.9 2.6 2 0 0 2 2 2 0 Heavy-metal resistance Arnt_C PF18583.1 KIK33046.1 - 0.061 12.9 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 Aminoarabinose transferase C-terminal domain ApoLp-III PF07464.11 KIK33046.1 - 0.11 12.6 4.5 1.9 8.6 0.8 2.6 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) KDZ PF18758.1 KIK33048.1 - 5.5e-83 278.0 0.0 8.3e-83 277.4 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK33048.1 - 0.046 13.9 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases YojJ PF10372.9 KIK33050.1 - 0.19 11.8 1.6 0.82 9.8 0.1 2.7 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus RNase_J_C PF17770.1 KIK33050.1 - 0.64 11.1 4.8 0.79 10.8 0.1 3.2 3 1 0 3 3 3 0 Ribonuclease J C-terminal domain KDZ PF18758.1 KIK33052.1 - 9.3e-67 224.9 0.2 1.6e-66 224.1 0.2 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK33052.1 - 0.0079 16.3 0.0 0.025 14.7 0.0 1.8 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases DUF1842 PF08896.10 KIK33052.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1842) WD40 PF00400.32 KIK33054.1 - 1.3e-11 44.8 1.2 2.5e-08 34.4 0.1 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.32 KIK33055.1 - 3e-08 34.2 0.8 5.1e-06 27.1 0.1 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33055.1 - 0.052 13.9 0.0 0.23 11.8 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Pro_isomerase PF00160.21 KIK33056.1 - 5.8e-44 150.1 0.0 8.2e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 KIK33056.1 - 8.3e-06 25.4 3.4 0.013 15.3 0.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK33056.1 - 9.3e-05 22.3 5.0 0.013 15.6 0.8 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK33056.1 - 0.0022 17.6 3.8 0.59 9.9 0.2 3.4 2 1 1 3 3 3 2 TPR repeat TPR_9 PF13371.6 KIK33056.1 - 0.011 15.9 0.7 0.039 14.1 0.6 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK33056.1 - 0.018 15.7 4.9 0.059 14.0 1.4 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK33056.1 - 0.02 15.7 2.8 0.02 15.7 2.8 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK33056.1 - 0.033 14.4 0.2 0.033 14.4 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIK33056.1 - 0.15 12.3 1.7 7.4 7.0 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Amidase PF01425.21 KIK33057.1 - 3.2e-71 240.7 0.0 1.9e-69 234.8 0.0 2.1 1 1 0 1 1 1 1 Amidase DUF4813 PF16072.5 KIK33057.1 - 0.017 14.8 1.1 0.031 13.9 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) KDZ PF18758.1 KIK33059.1 - 3.4e-79 265.6 0.0 5.9e-79 264.8 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK33059.1 - 0.0087 16.2 0.0 0.031 14.4 0.0 1.9 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Cauli_VI PF01693.16 KIK33060.1 - 9.6e-06 25.8 0.1 1.7e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin HMG_box PF00505.19 KIK33061.1 - 0.00017 21.9 3.3 0.00017 21.9 3.3 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK33061.1 - 0.0023 18.5 2.1 0.0023 18.5 2.1 2.2 3 0 0 3 3 3 1 HMG-box domain DUF3437 PF11919.8 KIK33061.1 - 0.02 14.8 1.5 0.11 12.4 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) 2-Hacid_dh PF00389.30 KIK33061.1 - 0.17 11.5 0.2 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Transposase_21 PF02992.14 KIK33063.1 - 6.9e-07 28.7 0.1 1.5e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 KIK33063.1 - 0.023 14.3 0.1 0.064 12.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Zn-C2H2_12 PF18112.1 KIK33063.1 - 0.14 12.6 3.7 0.57 10.7 3.7 2.1 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain Pkinase_Tyr PF07714.17 KIK33064.1 - 2.6e-37 128.5 0.0 3.5e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK33064.1 - 6.8e-30 104.3 0.0 9.9e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain MMR_HSR1 PF01926.23 KIK33064.1 - 0.00051 20.1 0.0 0.00099 19.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KIK33064.1 - 0.00092 18.8 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AIG1 PF04548.16 KIK33064.1 - 0.0027 17.0 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KIK33064.1 - 0.0041 17.0 0.0 0.0081 16.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KIK33064.1 - 0.006 17.0 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KIK33064.1 - 0.022 15.2 0.0 0.057 13.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Dynamin_N PF00350.23 KIK33064.1 - 0.026 14.6 0.0 0.056 13.5 0.0 1.6 1 0 0 1 1 1 0 Dynamin family Sigma54_activat PF00158.26 KIK33064.1 - 0.027 14.2 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Roc PF08477.13 KIK33064.1 - 0.077 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KIK33064.1 - 0.12 12.2 0.1 0.29 10.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 KIK33064.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Kdo PF06293.14 KIK33064.1 - 0.16 11.3 0.0 0.79 9.0 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 KIK33066.1 - 1.5e-44 149.1 25.3 3e-08 34.2 1.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33066.1 - 3e-22 78.7 3.1 1.8e-06 28.2 0.0 6.4 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK33066.1 - 2e-09 36.9 0.3 0.0032 16.5 0.0 4.7 1 1 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK33066.1 - 1.4e-05 23.9 4.4 0.18 10.4 0.4 3.8 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Frtz PF11768.8 KIK33066.1 - 1.6e-05 23.4 0.0 0.052 11.9 0.0 2.8 3 0 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 KIK33066.1 - 5.8e-05 23.5 8.1 1.7 9.2 0.0 5.9 6 1 1 7 7 6 2 PQQ-like domain WD40_like PF17005.5 KIK33066.1 - 0.00018 20.9 0.0 0.29 10.4 0.0 3.5 2 2 2 4 4 4 2 WD40-like domain Nbas_N PF15492.6 KIK33066.1 - 0.00097 18.5 2.3 0.017 14.5 0.0 3.3 3 2 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal BBS2_Mid PF14783.6 KIK33066.1 - 0.0023 18.0 0.0 0.3 11.2 0.0 3.1 3 2 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region PALB2_WD40 PF16756.5 KIK33066.1 - 0.005 15.8 5.3 0.68 8.8 0.2 3.1 2 1 0 2 2 2 2 Partner and localizer of BRCA2 WD40 domain Nucleoporin_N PF08801.11 KIK33066.1 - 0.0056 15.5 0.1 13 4.4 0.0 4.1 2 1 1 4 4 4 0 Nup133 N terminal like PD40 PF07676.12 KIK33066.1 - 0.0089 16.0 0.0 9.4 6.3 0.0 3.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Herpes_gI PF01688.17 KIK33066.1 - 0.034 14.1 0.0 0.13 12.1 0.0 1.9 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein I VID27 PF08553.10 KIK33066.1 - 0.057 12.5 0.1 3.3 6.7 0.0 2.3 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain RAB3GAP2_N PF14655.6 KIK33066.1 - 0.12 11.6 0.0 0.56 9.4 0.0 1.9 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus CHAP PF05257.16 KIK33066.1 - 0.22 12.1 5.0 4.1 8.1 0.0 3.8 4 1 0 4 4 4 0 CHAP domain Hex_IIIa PF02455.16 KIK33067.1 - 0.0061 15.4 0.0 0.0077 15.1 0.0 1.1 1 0 0 1 1 1 1 Hexon-associated protein (IIIa) DUF5082 PF16888.5 KIK33067.1 - 0.0088 16.3 0.9 0.017 15.4 0.3 1.7 2 1 0 2 2 2 1 Domain of unknown function (DUF5082) RTX_C PF08339.10 KIK33067.1 - 0.019 15.1 0.5 0.039 14.0 0.5 1.5 1 0 0 1 1 1 0 RTX C-terminal domain LBP_BPI_CETP PF01273.25 KIK33067.1 - 0.024 14.3 1.5 1.8 8.1 0.4 2.4 1 1 1 2 2 2 0 LBP / BPI / CETP family, N-terminal domain DUF2267 PF10025.9 KIK33067.1 - 0.058 13.7 0.3 1.8 8.9 1.1 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) HisKA_3 PF07730.13 KIK33067.1 - 0.12 12.9 0.6 1 10.0 0.0 2.7 1 1 0 2 2 2 0 Histidine kinase CorA PF01544.18 KIK33067.1 - 0.22 10.8 6.0 1.8 7.8 6.0 2.1 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein PEP-utilisers_N PF05524.13 KIK33067.1 - 0.24 11.6 1.8 0.53 10.5 1.8 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF1269 PF06897.12 KIK33067.1 - 0.55 10.5 2.7 3.8 7.9 2.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1269) Herpes_BLRF2 PF05812.12 KIK33067.1 - 0.72 10.0 4.0 0.94 9.6 2.1 2.0 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein DUF1664 PF07889.12 KIK33067.1 - 0.83 9.7 4.4 9.1 6.3 0.0 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) zf-RVT PF13966.6 KIK33071.1 - 6e-06 26.9 0.1 8.5e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase U5_2-snRNA_bdg PF10597.9 KIK33071.1 - 0.16 12.0 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 U5-snRNA binding site 2 of PrP8 Sugar_tr PF00083.24 KIK33073.1 - 7.3e-102 341.5 26.3 8.9e-102 341.3 26.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK33073.1 - 1.9e-23 83.0 52.1 4.1e-22 78.6 24.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Retrotrans_gag PF03732.17 KIK33076.1 - 1.3e-06 28.6 0.1 2.5e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 KIK33076.1 - 0.00076 19.4 2.0 0.00076 19.4 2.0 1.7 2 0 0 2 2 2 1 Zinc knuckle Asp_protease_2 PF13650.6 KIK33077.1 - 2.3e-05 24.9 0.0 4.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK33077.1 - 4.1e-05 24.0 0.0 8.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KIK33077.1 - 0.00023 21.0 0.0 0.00035 20.3 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 KIK33077.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease p450 PF00067.22 KIK33080.1 - 7.7e-39 133.7 0.3 4e-28 98.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 WD40 PF00400.32 KIK33081.1 - 1.1e-123 399.5 64.4 5.8e-10 39.6 0.3 14.9 15 0 0 15 15 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33081.1 - 4.4e-33 113.4 14.0 0.0029 17.9 0.0 12.9 1 1 13 14 14 14 8 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KIK33081.1 - 9.6e-19 67.4 14.6 0.00047 19.0 1.2 10.7 1 1 8 10 10 10 5 Nup133 N terminal like Ge1_WD40 PF16529.5 KIK33081.1 - 4.2e-17 62.1 7.2 0.065 12.2 0.0 10.9 2 2 7 12 12 12 5 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK33081.1 - 1.5e-16 60.6 0.0 0.078 12.3 0.0 10.5 6 2 2 10 10 10 3 WD40-like domain PD40 PF07676.12 KIK33081.1 - 5.6e-16 58.0 8.2 1 9.4 0.0 11.4 13 0 0 13 13 12 4 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK33081.1 - 5.3e-11 41.9 13.3 0.72 8.4 0.1 12.2 9 4 5 14 14 14 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KIK33081.1 - 2.7e-09 37.2 15.0 0.24 11.9 0.0 10.7 7 4 5 12 12 12 1 PQQ-like domain BBS2_Mid PF14783.6 KIK33081.1 - 9.7e-09 35.2 3.6 21 5.2 0.0 10.7 11 1 0 11 11 11 0 Ciliary BBSome complex subunit 2, middle region Peptidase_S9_N PF02897.15 KIK33081.1 - 5.7e-07 28.7 2.7 5.5 5.7 0.0 7.6 4 3 7 11 11 11 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Frtz PF11768.8 KIK33081.1 - 1.5e-06 26.9 0.0 2.4 6.3 0.0 6.4 2 2 3 8 8 8 2 WD repeat-containing and planar cell polarity effector protein Fritz PQQ PF01011.21 KIK33081.1 - 0.00011 22.0 0.0 1.5e+02 2.6 0.1 7.9 10 0 0 10 10 10 0 PQQ enzyme repeat DUF4402 PF14352.6 KIK33081.1 - 0.00036 21.2 16.8 0.091 13.4 0.7 6.6 2 2 6 8 8 8 1 Domain of unknown function (DUF4402) Cuticle_4 PF15955.5 KIK33081.1 - 0.0054 17.4 9.0 58 4.5 0.0 7.5 9 0 0 9 9 8 0 Cuticle protein DUF5570 PF17731.1 KIK33081.1 - 0.0066 16.5 20.8 0.14 12.3 0.3 6.7 6 2 1 7 7 7 1 Family of unknown function (DUF5570) DUF4265 PF14085.6 KIK33081.1 - 0.35 10.9 3.6 21 5.1 0.0 5.4 9 0 0 9 9 6 0 Domain of unknown function (DUF4265) Sirohm_synth_M PF14824.6 KIK33081.1 - 9.9 5.7 7.2 6.8 6.2 0.1 3.5 4 0 0 4 4 4 0 Sirohaem biosynthesis protein central DUF4413 PF14372.6 KIK33084.1 - 0.00019 21.7 0.2 0.00027 21.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) DASH_Duo1 PF08651.10 KIK33084.1 - 0.046 13.5 0.3 0.3 10.9 0.0 2.3 2 1 1 3 3 3 0 DASH complex subunit Duo1 Dimer_Tnp_hAT PF05699.14 KIK33085.1 - 3.9e-18 65.0 0.2 4.6e-18 64.8 0.2 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DDE_3 PF13358.6 KIK33086.1 - 0.014 15.2 0.2 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 DDE superfamily endonuclease PikAIV_N PF18605.1 KIK33087.1 - 0.11 12.1 0.7 0.21 11.2 0.7 1.5 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Titin_Ig-rpts PF06582.12 KIK33088.1 - 0.0016 18.3 0.1 0.021 14.7 0.0 2.7 3 0 0 3 3 3 1 Titin repeat WD40 PF00400.32 KIK33089.1 - 1.3e-12 48.0 0.3 4.4e-10 40.0 0.3 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.8 KIK33089.1 - 0.00052 18.8 0.0 0.00054 18.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KIK33089.1 - 0.014 15.6 0.0 0.025 14.9 0.0 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK33091.1 - 5.7e-24 83.9 16.7 5.2e-09 36.6 3.3 6.3 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33091.1 - 1.2e-18 67.1 0.8 0.0053 17.0 0.0 5.9 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK33091.1 - 9.4e-07 28.1 0.1 0.57 9.1 0.0 3.9 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK33091.1 - 2.5e-06 27.0 0.2 2.2 7.6 0.0 4.9 2 2 4 6 6 6 3 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KIK33091.1 - 1.4e-05 24.9 3.6 14 5.8 0.0 5.9 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK33091.1 - 3e-05 22.9 0.4 0.74 8.4 0.2 3.2 2 1 0 3 3 3 3 Nucleoporin Nup120/160 PQQ PF01011.21 KIK33091.1 - 0.00045 20.0 1.1 22 5.2 0.0 4.8 4 0 0 4 4 4 0 PQQ enzyme repeat Lactonase PF10282.9 KIK33091.1 - 0.0019 17.5 0.0 0.0057 16.0 0.0 1.8 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller WD40_like PF17005.5 KIK33091.1 - 0.004 16.5 0.0 0.14 11.5 0.0 2.7 2 1 0 3 3 3 1 WD40-like domain PQQ_3 PF13570.6 KIK33091.1 - 0.0095 16.4 5.0 2.3 8.8 0.0 3.1 3 0 0 3 3 3 2 PQQ-like domain RAB3GAP2_N PF14655.6 KIK33091.1 - 0.045 13.0 0.1 0.08 12.2 0.1 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus CRT10 PF08728.10 KIK33091.1 - 0.062 11.5 0.0 0.097 10.8 0.0 1.2 1 0 0 1 1 1 0 CRT10 Dimer_Tnp_hAT PF05699.14 KIK33092.1 - 6.5e-14 51.5 0.0 8.3e-14 51.1 0.0 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Trehalose_PPase PF02358.16 KIK33093.1 - 1.6e-51 174.7 0.0 1.5e-35 122.5 0.0 2.8 2 1 1 3 3 3 2 Trehalose-phosphatase MutS_II PF05188.17 KIK33093.1 - 2.2e-05 24.7 0.0 0.00049 20.4 0.0 2.2 2 0 0 2 2 2 1 MutS domain II Hydrolase_3 PF08282.12 KIK33093.1 - 0.019 14.7 0.0 1.1 9.0 0.0 2.2 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase UAA PF08449.11 KIK33094.1 - 8.3e-65 219.0 7.7 4.2e-64 216.6 7.7 1.8 1 1 0 1 1 1 1 UAA transporter family HSP70 PF00012.20 KIK33097.1 - 1.7e-26 92.6 2.9 3.9e-24 84.8 0.7 2.1 2 0 0 2 2 2 2 Hsp70 protein SR-25 PF10500.9 KIK33097.1 - 0.61 9.6 9.3 1.5 8.3 1.8 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DEAD PF00270.29 KIK33099.1 - 2.7e-10 40.3 0.0 7.6e-10 38.8 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK33099.1 - 1.4e-09 38.3 0.0 7.9e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK33099.1 - 0.015 15.3 0.0 0.051 13.6 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PH_16 PF17838.1 KIK33099.1 - 0.23 11.3 0.7 0.61 9.9 0.7 1.7 1 1 0 1 1 1 0 PH domain PRKG1_interact PF15898.5 KIK33099.1 - 0.72 10.8 3.2 2 9.4 3.2 1.7 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain zf-RING_UBOX PF13445.6 KIK33101.1 - 2.6e-05 24.2 7.0 5.1e-05 23.2 7.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIK33101.1 - 0.0003 21.1 7.1 0.00056 20.2 7.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK33101.1 - 0.00054 19.7 6.3 0.001 18.9 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK33101.1 - 0.0016 18.3 6.1 0.0031 17.3 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK33101.1 - 0.0027 17.8 5.3 0.0051 16.9 5.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF3584 PF12128.8 KIK33101.1 - 0.0034 15.0 4.5 0.0044 14.6 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) zf-RING_10 PF16685.5 KIK33101.1 - 0.0048 17.0 3.1 0.012 15.8 3.1 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 HAUS5 PF14817.6 KIK33101.1 - 0.0051 15.7 3.8 0.0059 15.4 3.8 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 zf-C3HC4_3 PF13920.6 KIK33101.1 - 0.006 16.4 4.7 0.011 15.5 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KIK33101.1 - 0.015 15.1 2.0 0.026 14.4 2.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 KIK33101.1 - 0.018 15.0 6.0 0.033 14.1 6.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain GrpE PF01025.19 KIK33101.1 - 0.019 14.6 2.1 0.028 14.1 2.1 1.3 1 0 0 1 1 1 0 GrpE Vps54_N PF10475.9 KIK33101.1 - 0.023 14.0 1.0 0.033 13.5 1.0 1.1 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Exonuc_VII_L PF02601.15 KIK33101.1 - 0.03 13.9 1.6 0.035 13.7 1.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-CpG_bind_C PF12269.8 KIK33101.1 - 0.049 13.4 2.2 0.07 12.9 2.2 1.2 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Spc7 PF08317.11 KIK33101.1 - 0.079 11.8 5.4 0.1 11.4 5.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Macoilin PF09726.9 KIK33101.1 - 0.11 11.1 6.2 0.13 10.8 6.2 1.0 1 0 0 1 1 1 0 Macoilin family DUF4407 PF14362.6 KIK33101.1 - 0.16 11.3 1.2 0.19 11.0 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SWIRM-assoc_1 PF16495.5 KIK33101.1 - 0.19 11.7 8.6 0.2 11.6 7.9 1.4 1 1 0 1 1 1 0 SWIRM-associated region 1 Prok-RING_4 PF14447.6 KIK33101.1 - 0.41 10.5 5.8 0.9 9.5 5.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KIK33101.1 - 1.4 8.6 8.7 16 5.2 0.7 2.2 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type OmpH PF03938.14 KIK33101.1 - 2.3 8.6 10.0 3.3 8.1 10.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Fzo_mitofusin PF04799.13 KIK33101.1 - 4.5 6.8 7.6 6.6 6.3 7.6 1.1 1 0 0 1 1 1 0 fzo-like conserved region SlyX PF04102.12 KIK33101.1 - 6 7.6 9.4 65 4.3 8.3 2.3 1 1 0 1 1 1 0 SlyX Ribonuclease_P PF00825.18 KIK33103.1 - 0.0045 17.0 0.6 0.0088 16.1 0.6 1.4 1 0 0 1 1 1 1 Ribonuclease P Glyco_hydro_3 PF00933.21 KIK33105.1 - 2.2e-26 93.0 0.0 2.8e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain WD40 PF00400.32 KIK33107.1 - 2.1e-30 104.3 6.5 6.4e-09 36.3 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33107.1 - 1.4e-09 38.2 0.3 0.015 15.6 0.0 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK33107.1 - 0.00014 20.6 0.0 0.24 10.0 0.0 2.7 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK33107.1 - 0.0045 16.0 0.0 0.14 11.1 0.0 2.7 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Crr6 PF08847.11 KIK33108.1 - 0.064 12.9 0.0 0.073 12.7 0.0 1.1 1 0 0 1 1 1 0 Chlororespiratory reduction 6 STALD PF18185.1 KIK33109.1 - 0.041 13.2 0.2 0.095 12.0 0.1 1.7 1 1 0 1 1 1 0 Sir2- and TIR-associating SLOG family DUF1846 PF08903.11 KIK33109.1 - 0.087 11.4 2.4 0.12 10.9 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) ALMT PF11744.8 KIK33109.1 - 0.2 10.4 4.3 0.24 10.2 4.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter AvrM-A PF18241.1 KIK33109.1 - 0.34 11.3 13.5 0.53 10.7 13.5 1.4 1 1 0 1 1 1 0 Flax-rust effector AvrM-A Occludin_ELL PF07303.13 KIK33109.1 - 1.2 9.9 7.8 0.26 12.0 2.4 2.0 1 1 1 2 2 2 0 Occludin homology domain RT_RNaseH PF17917.1 KIK33110.1 - 0.00034 20.9 0.0 0.00049 20.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2439 PF10382.9 KIK33110.1 - 0.036 14.4 0.0 0.057 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2439) DUF1327 PF07041.11 KIK33110.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) RT_RNaseH_2 PF17919.1 KIK33111.1 - 7.4e-10 38.8 0.0 8.7e-10 38.5 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KIK33111.1 - 0.021 15.1 0.0 0.028 14.7 0.0 1.2 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase R3H PF01424.22 KIK33112.1 - 0.12 12.4 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 R3H domain DUF4912 PF16258.5 KIK33113.1 - 0.014 15.6 0.0 0.019 15.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4912) PigN PF04987.14 KIK33115.1 - 0.035 13.0 1.2 0.044 12.7 1.2 1.1 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) NLE PF08154.12 KIK33117.1 - 3.9e-14 52.9 0.1 7.9e-14 51.9 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 KIK33117.1 - 5.9e-09 36.4 7.5 0.043 14.7 0.0 5.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 KIK33117.1 - 0.0052 15.5 0.1 0.95 8.0 0.0 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 TauD PF02668.16 KIK33121.1 - 9.6e-06 25.6 0.1 0.00013 21.9 0.1 2.1 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MIS13 PF08202.11 KIK33122.1 - 0.028 13.7 0.5 0.046 13.0 0.5 1.3 1 0 0 1 1 1 0 Mis12-Mtw1 protein family API5 PF05918.11 KIK33122.1 - 0.079 11.8 0.8 0.1 11.4 0.8 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) WD40 PF00400.32 KIK33125.1 - 4.8e-122 394.3 61.8 5.6e-10 39.7 0.2 14.8 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33125.1 - 1.9e-45 153.1 0.1 0.00061 20.0 0.0 13.8 1 1 12 14 14 14 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK33125.1 - 3.5e-34 118.2 5.9 0.028 13.4 0.0 13.3 3 2 8 14 14 14 12 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK33125.1 - 1.5e-15 56.8 9.5 0.25 10.0 0.0 11.5 6 3 6 13 13 13 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK33125.1 - 5.5e-15 55.5 0.0 0.00076 18.9 0.0 7.8 6 2 2 8 8 8 3 WD40-like domain PD40 PF07676.12 KIK33125.1 - 9.5e-15 54.1 20.1 3.4 7.7 0.0 11.9 13 0 0 13 13 12 4 WD40-like Beta Propeller Repeat Peptidase_S9_N PF02897.15 KIK33125.1 - 3.5e-06 26.1 0.0 0.91 8.2 0.0 6.0 3 2 3 6 6 6 1 Prolyl oligopeptidase, N-terminal beta-propeller domain AAA_16 PF13191.6 KIK33125.1 - 2.3e-05 24.8 0.0 0.0002 21.8 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain Frtz PF11768.8 KIK33125.1 - 3.6e-05 22.3 0.0 2.2 6.5 0.0 5.0 3 2 3 6 6 6 2 WD repeat-containing and planar cell polarity effector protein Fritz NACHT PF05729.12 KIK33125.1 - 0.00013 21.9 0.0 0.00027 20.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain WD40_3 PF15911.5 KIK33125.1 - 0.00038 20.4 1.5 13 5.9 0.0 6.4 7 1 1 8 8 8 0 WD domain, G-beta repeat PQQ_2 PF13360.6 KIK33125.1 - 0.0013 18.3 3.7 0.0013 18.3 3.7 3.9 2 2 1 3 3 3 1 PQQ-like domain AAA PF00004.29 KIK33125.1 - 0.0021 18.5 0.0 0.0045 17.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF5570 PF17731.1 KIK33125.1 - 0.0063 16.6 26.4 5 7.2 0.7 9.5 6 3 6 12 12 11 1 Family of unknown function (DUF5570) SEF14_adhesin PF06443.11 KIK33125.1 - 0.018 14.9 0.1 0.018 14.9 0.1 4.4 4 1 1 5 5 5 0 SEF14-like adhesin Nbas_N PF15492.6 KIK33125.1 - 0.06 12.7 13.8 57 2.9 0.0 9.0 9 3 2 12 12 12 0 Neuroblastoma-amplified sequence, N terminal Parvo_NS1 PF01057.17 KIK33125.1 - 0.067 12.3 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PQQ PF01011.21 KIK33125.1 - 0.098 12.6 3.9 4.1 7.5 0.1 4.8 6 0 0 6 6 6 0 PQQ enzyme repeat NB-ARC PF00931.22 KIK33125.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KIK33125.1 - 0.13 12.6 0.0 0.53 10.7 0.0 2.1 1 0 0 1 1 1 0 RNA helicase CxC6 PF18721.1 KIK33126.1 - 1.2e-20 73.6 8.2 1.2e-20 73.6 8.2 3.0 3 0 0 3 3 3 1 CxC6 like cysteine cluster associated with KDZ transposases CHAT PF12770.7 KIK33128.1 - 6e-41 140.7 0.0 1.1e-40 139.9 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK33128.1 - 5.7e-06 26.0 9.9 0.0061 16.4 0.5 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat GATase_4 PF13230.6 KIK33128.1 - 0.028 13.3 0.0 5.7 5.8 0.0 2.8 1 1 2 3 3 3 0 Glutamine amidotransferases class-II NS3_envE PF02723.14 KIK33129.1 - 0.17 12.0 6.1 0.75 9.9 0.1 2.1 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E TraP PF07296.11 KIK33129.1 - 0.2 10.9 0.3 0.31 10.2 0.3 1.3 1 0 0 1 1 1 0 TraP protein RRM_1 PF00076.22 KIK33130.1 - 2.1e-29 101.2 3.3 3.1e-09 36.5 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIK33130.1 - 0.00032 20.7 0.1 1.4 9.0 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif RRM_occluded PF16842.5 KIK33130.1 - 0.0037 17.1 0.0 25 4.8 0.0 4.1 4 0 0 4 4 4 1 Occluded RNA-recognition motif NID PF07292.13 KIK33130.1 - 0.043 14.5 0.0 18 6.1 0.0 3.2 3 0 0 3 3 3 0 Nmi/IFP 35 domain (NID) RRM_7 PF16367.5 KIK33130.1 - 0.13 12.4 0.0 3 8.0 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif Chorion_1 PF01723.16 KIK33130.1 - 0.16 11.9 2.1 0.49 10.3 2.1 1.8 1 0 0 1 1 1 0 Chorion protein polyprenyl_synt PF00348.17 KIK33131.1 - 1e-54 185.3 0.0 1.3e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase TPR_1 PF00515.28 KIK33132.1 - 7.6e-06 25.5 0.0 0.15 11.9 0.0 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK33132.1 - 5.9e-05 22.9 0.1 1.5 9.1 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK33132.1 - 0.0079 16.1 0.0 0.18 11.9 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Peptidase_S26 PF10502.9 KIK33133.1 - 8.4e-06 25.6 0.0 0.0032 17.2 0.0 2.2 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 KIK33133.1 - 0.033 14.1 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase S24-like PAXNEB PF05625.11 KIK33135.1 - 3e-51 174.7 0.0 4.6e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 PAXNEB protein WD40 PF00400.32 KIK33140.1 - 1.4e-08 35.2 11.6 0.0059 17.4 0.0 5.2 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33140.1 - 5.5e-06 26.6 0.0 0.028 14.7 0.1 4.4 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KIK33140.1 - 0.011 16.2 3.6 1 10.0 0.4 3.9 3 1 0 3 3 3 0 PQQ-like domain Spt5_N PF11942.8 KIK33141.1 - 0.0097 16.9 4.1 0.017 16.1 4.1 1.5 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal PPV_E1_N PF00524.18 KIK33141.1 - 0.029 14.8 2.8 0.065 13.7 2.8 1.5 1 0 0 1 1 1 0 E1 Protein, N terminal domain MRP-S24 PF14955.6 KIK33142.1 - 0.064 13.2 0.6 0.09 12.7 0.6 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S24 MLTR_LBD PF17765.1 KIK33144.1 - 0.0049 17.0 0.1 0.006 16.7 0.1 1.2 1 0 0 1 1 1 1 MmyB-like transcription regulator ligand binding domain Dimer_Tnp_hAT PF05699.14 KIK33146.1 - 7.1e-11 41.7 0.1 8.6e-11 41.5 0.1 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region F-box-like PF12937.7 KIK33147.1 - 1e-08 34.9 3.5 2e-08 34.0 3.5 1.5 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK33147.1 - 0.46 10.4 4.3 2.9 7.9 0.1 2.7 2 0 0 2 2 2 0 F-box domain WD40 PF00400.32 KIK33148.1 - 1.6e-41 139.5 22.1 7.6e-07 29.7 3.6 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33148.1 - 1.7e-19 69.9 7.1 0.001 19.4 0.2 5.3 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK33148.1 - 4.6e-07 28.9 3.0 0.27 9.8 0.0 4.1 2 1 3 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK33148.1 - 5.7e-07 28.8 0.1 0.064 12.2 0.0 4.3 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_S9_N PF02897.15 KIK33148.1 - 0.00057 18.8 2.2 0.13 11.0 0.1 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF1513 PF07433.11 KIK33148.1 - 0.0014 17.8 2.0 8 5.4 0.2 4.0 1 1 2 4 4 4 1 Protein of unknown function (DUF1513) Gmad1 PF10647.9 KIK33148.1 - 0.0045 16.8 2.1 0.046 13.5 2.0 2.3 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain WD40_like PF17005.5 KIK33148.1 - 0.0062 15.9 0.0 3 7.1 0.0 3.3 2 1 1 4 4 4 1 WD40-like domain Nucleoporin_N PF08801.11 KIK33148.1 - 0.013 14.3 0.1 7.5 5.2 0.0 3.5 3 1 0 4 4 4 0 Nup133 N terminal like PALB2_WD40 PF16756.5 KIK33148.1 - 0.019 13.9 10.0 0.88 8.4 2.0 3.7 3 2 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Cytochrom_D1 PF02239.16 KIK33148.1 - 0.023 13.3 0.2 0.44 9.0 0.2 2.7 2 1 1 3 3 3 0 Cytochrome D1 heme domain PD40 PF07676.12 KIK33148.1 - 0.028 14.4 0.1 28 4.8 0.0 4.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF5570 PF17731.1 KIK33148.1 - 0.12 12.5 2.1 0.86 9.7 0.2 2.9 1 1 2 3 3 3 0 Family of unknown function (DUF5570) PQQ PF01011.21 KIK33148.1 - 0.17 11.9 2.2 29 4.8 0.2 4.0 5 0 0 5 5 5 0 PQQ enzyme repeat IKI3 PF04762.12 KIK33148.1 - 0.55 8.2 1.8 18 3.1 1.0 2.8 2 1 0 2 2 2 0 IKI3 family WD40 PF00400.32 KIK33149.1 - 2.1e-21 75.8 15.0 1.4e-07 32.1 3.3 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33149.1 - 2.7e-13 50.0 0.3 0.0031 17.8 0.1 4.6 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK33149.1 - 8.9e-08 31.9 0.1 2.1 8.4 0.1 5.0 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK33149.1 - 2.5e-07 30.0 0.2 0.00097 18.2 0.0 2.5 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK33149.1 - 0.00017 21.5 0.9 0.02 14.7 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KIK33149.1 - 0.00032 20.1 0.3 0.0094 15.3 0.1 2.6 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK33149.1 - 0.00064 18.5 1.7 0.23 10.1 0.3 3.1 1 1 2 3 3 3 1 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KIK33149.1 - 0.0027 18.2 2.2 1.6 9.4 0.9 3.1 2 1 1 3 3 3 2 PQQ-like domain PQQ PF01011.21 KIK33149.1 - 0.014 15.3 0.0 39 4.4 0.0 4.3 4 0 0 4 4 4 0 PQQ enzyme repeat DUF1513 PF07433.11 KIK33149.1 - 0.085 11.9 0.3 9 5.3 0.0 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1513) Proteasome_A_N PF10584.9 KIK33149.1 - 6.7 6.5 5.5 11 5.8 0.0 3.5 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature F-box-like PF12937.7 KIK33152.1 - 0.0034 17.2 0.1 0.012 15.4 0.1 2.0 1 0 0 1 1 1 1 F-box-like KDZ PF18758.1 KIK33153.1 - 4.5e-60 203.0 0.0 9.2e-60 202.0 0.0 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK33153.1 - 8.2e-42 141.7 0.1 1.7e-41 140.7 0.1 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK33153.1 - 0.0098 16.0 0.1 0.024 14.8 0.1 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases DUF948 PF06103.11 KIK33156.1 - 0.17 12.2 0.9 1.3 9.3 0.8 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) RAP80_UIM PF18282.1 KIK33156.1 - 0.67 9.8 13.6 0.041 13.6 6.5 2.7 1 1 1 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif ANAPC4_WD40 PF12894.7 KIK33158.1 - 2.8e-05 24.3 0.7 0.014 15.7 0.3 3.4 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK33158.1 - 0.049 14.5 3.8 0.49 11.4 0.0 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat Pkinase PF00069.25 KIK33160.1 - 8.3e-37 127.0 0.0 8.6e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK33160.1 - 8.3e-16 58.0 0.0 9.3e-16 57.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK33160.1 - 0.007 16.3 0.2 0.012 15.5 0.1 1.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KIK33160.1 - 0.05 12.6 0.0 0.063 12.3 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 KIK33160.1 - 0.083 11.8 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 KIK33160.1 - 0.13 11.2 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain SDA1 PF05285.12 KIK33161.1 - 0.14 11.5 3.5 0.17 11.3 3.5 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KIK33161.1 - 1.3 7.1 9.5 1.8 6.7 9.5 1.1 1 0 0 1 1 1 0 Nop14-like family 5_3_exonuc_N PF02739.16 KIK33162.1 - 0.027 14.4 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain Cauli_VI PF01693.16 KIK33163.1 - 1.2e-06 28.7 0.3 1.7e-06 28.2 0.3 1.2 1 0 0 1 1 1 1 Caulimovirus viroplasmin KDZ PF18758.1 KIK33164.1 - 3.2e-64 216.6 1.0 5.1e-64 216.0 1.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK33164.1 - 9.7e-44 147.9 0.0 2.3e-43 146.7 0.0 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK33164.1 - 9e-07 29.0 0.0 2.3e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK33164.1 - 0.079 12.8 0.8 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases Rpn9_C PF18261.1 KIK33164.1 - 0.2 11.3 0.7 20 4.9 0.1 2.7 2 0 0 2 2 2 0 Rpn9 C-terminal helix zf-B_box PF00643.24 KIK33164.1 - 1.5 9.0 13.5 0.043 14.0 5.8 2.5 2 0 0 2 2 2 0 B-box zinc finger LegC3_N PF18654.1 KIK33165.1 - 0.15 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain WD40 PF00400.32 KIK33168.1 - 8.7e-24 83.4 0.1 0.00055 20.7 0.0 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KIK33168.1 - 1.2e-06 27.7 0.4 0.19 10.7 0.0 3.6 1 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KIK33168.1 - 5.9e-06 26.5 0.0 0.73 10.2 0.0 3.4 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK33175.1 - 4.7e-12 46.2 0.7 1.7e-11 44.5 0.7 2.0 1 0 0 1 1 1 1 WD domain, G-beta repeat AAA_16 PF13191.6 KIK33175.1 - 8.1e-07 29.6 0.1 2.2e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK33175.1 - 5.3e-06 26.5 0.0 1.4e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 KIK33175.1 - 0.00046 20.4 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK33175.1 - 0.0073 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Parvo_NS1 PF01057.17 KIK33175.1 - 0.03 13.4 0.5 0.068 12.3 0.5 1.7 1 1 0 1 1 1 0 Parvovirus non-structural protein NS1 APS_kinase PF01583.20 KIK33175.1 - 0.057 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.29 KIK33175.1 - 0.072 13.5 0.0 0.25 11.7 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoU PF01895.19 KIK33175.1 - 0.22 12.0 0.8 1.2 9.7 0.1 2.4 2 0 0 2 2 2 0 PhoU domain Oxidored_FMN PF00724.20 KIK33177.1 - 2.1e-93 313.3 0.0 2.4e-93 313.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.21 KIK33177.1 - 0.097 12.6 0.1 0.45 10.5 0.0 2.1 2 0 0 2 2 2 0 Tautomerase enzyme CxC2 PF18803.1 KIK33179.1 - 1.8e-43 147.1 0.2 1.8e-43 147.1 0.2 1.9 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK33179.1 - 1.6e-07 31.4 0.1 3.2e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK33179.1 - 7e-05 22.6 0.1 7e-05 22.6 0.1 2.1 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 KIK33179.1 - 4.7 7.4 15.6 4.4 7.5 13.7 2.0 1 1 1 2 2 2 0 B-box zinc finger TPR_2 PF07719.17 KIK33180.1 - 0.0075 16.3 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat U3_assoc_6 PF08640.11 KIK33180.1 - 0.011 15.8 0.7 0.011 15.8 0.7 1.9 1 1 1 2 2 2 0 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KIK33180.1 - 0.029 15.2 0.0 0.066 14.1 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat HAT PF02184.16 KIK33180.1 - 0.07 13.1 0.0 0.07 13.1 0.0 2.7 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat SMBP PF16785.5 KIK33182.1 - 0.088 13.0 0.2 0.16 12.2 0.1 1.5 2 0 0 2 2 2 0 Small metal-binding protein Oxidored_FMN PF00724.20 KIK33183.1 - 7.5e-39 133.9 0.1 6.1e-33 114.5 0.0 2.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family DUF1658 PF07871.11 KIK33186.1 - 0.075 13.0 0.5 0.075 13.0 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) DUF3439 PF11921.8 KIK33186.1 - 0.22 11.5 4.7 0.35 10.9 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) WD40 PF00400.32 KIK33187.1 - 9.1e-40 133.9 9.5 5.5e-08 33.4 0.5 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33187.1 - 5.3e-17 61.9 5.2 1.1e-06 28.8 0.1 5.7 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK33187.1 - 4.7e-07 29.9 0.1 6e-05 23.0 0.1 2.5 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK33187.1 - 5e-06 25.5 4.0 0.16 10.6 0.2 3.4 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KIK33187.1 - 0.00029 19.5 0.0 0.34 9.4 0.1 2.5 3 0 0 3 3 3 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KIK33187.1 - 0.00077 18.5 0.0 0.92 8.4 0.0 4.1 2 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 KIK33187.1 - 0.00092 19.6 2.7 1.7 9.3 0.0 4.2 3 1 1 4 4 4 1 PQQ-like domain WD40_like PF17005.5 KIK33187.1 - 0.0015 17.9 0.0 0.012 15.0 0.0 2.4 3 1 1 4 4 4 1 WD40-like domain PQQ PF01011.21 KIK33187.1 - 0.0078 16.1 0.0 4.3 7.4 0.0 4.0 4 0 0 4 4 4 1 PQQ enzyme repeat Nbas_N PF15492.6 KIK33187.1 - 0.039 13.3 0.2 1.8 7.8 0.0 3.2 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 KIK33187.1 - 0.085 11.8 0.8 2.1 7.2 0.1 2.4 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Cut8 PF08559.10 KIK33188.1 - 0.029 14.0 1.0 0.032 13.8 1.0 1.0 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein WBP-1 PF11669.8 KIK33188.1 - 0.046 14.4 0.6 0.046 14.4 0.6 1.9 1 1 1 2 2 2 0 WW domain-binding protein 1 Mucin PF01456.17 KIK33188.1 - 0.5 10.4 11.8 0.13 12.3 3.6 2.1 1 1 1 2 2 2 0 Mucin-like glycoprotein WD40 PF00400.32 KIK33189.1 - 2.3e-14 53.6 6.7 2e-06 28.4 0.2 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33189.1 - 2e-08 34.4 0.6 7.7e-07 29.3 0.4 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK33189.1 - 0.0001 21.1 0.0 0.25 9.9 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK33189.1 - 0.00013 21.4 0.1 0.045 13.1 0.0 2.0 1 1 1 2 2 2 2 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.6 KIK33189.1 - 0.0031 17.1 0.3 0.0036 16.9 0.3 1.1 1 0 0 1 1 1 1 PQQ-like domain WD40_like PF17005.5 KIK33189.1 - 0.0053 16.1 0.0 0.039 13.3 0.0 1.9 1 1 1 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 KIK33189.1 - 0.0056 15.7 0.0 0.066 12.2 0.0 1.9 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 KIK33189.1 - 0.0094 15.8 0.0 0.58 10.2 0.2 2.4 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_3 PF13570.6 KIK33189.1 - 0.02 15.4 0.1 3.8 8.1 0.3 2.5 2 1 0 2 2 2 0 PQQ-like domain RAB3GAP2_N PF14655.6 KIK33189.1 - 0.035 13.4 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ketoacyl-synt_C PF02801.22 KIK33189.1 - 0.064 13.3 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain PepSY PF03413.19 KIK33189.1 - 0.074 13.6 0.3 0.4 11.3 0.3 2.0 1 1 0 1 1 1 0 Peptidase propeptide and YPEB domain Dimer_Tnp_hAT PF05699.14 KIK33190.1 - 0.029 14.2 0.1 0.036 13.8 0.1 1.2 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF104 PF01954.16 KIK33191.1 - 0.056 13.9 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF104 FAM92 PF06730.11 KIK33192.1 - 0.021 14.2 0.1 0.024 14.1 0.1 1.1 1 0 0 1 1 1 0 FAM92 protein DUF104 PF01954.16 KIK33193.1 - 0.033 14.6 0.0 0.064 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF104 Aminotran_3 PF00202.21 KIK33194.1 - 0.2 10.3 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-III WD40 PF00400.32 KIK33196.1 - 8.6e-22 77.0 10.8 6e-08 33.2 0.3 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33196.1 - 4.2e-06 27.0 0.1 0.035 14.4 0.0 4.1 2 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK33196.1 - 1.4e-05 24.0 0.0 0.036 12.7 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK33196.1 - 0.00069 18.7 0.2 0.79 8.6 0.0 2.5 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK33196.1 - 0.0045 16.9 1.0 26 4.9 0.0 4.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Antig_Caf1 PF09255.10 KIK33196.1 - 0.041 14.0 0.5 0.44 10.7 0.1 2.2 2 0 0 2 2 2 0 Caf1 Capsule antigen WD40 PF00400.32 KIK33197.1 - 4.9e-10 39.8 2.8 6.7e-10 39.4 0.2 2.7 3 0 0 3 3 2 1 WD domain, G-beta repeat AAA_16 PF13191.6 KIK33197.1 - 2.5e-05 24.7 0.0 0.00013 22.4 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KIK33197.1 - 4.3e-05 23.5 0.0 0.00012 22.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Parvo_NS1 PF01057.17 KIK33197.1 - 0.0038 16.3 0.1 0.0067 15.6 0.1 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 KIK33197.1 - 0.0082 15.4 0.0 0.019 14.2 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain ANAPC4_WD40 PF12894.7 KIK33197.1 - 0.0082 16.4 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK33197.1 - 0.015 14.3 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_22 PF13401.6 KIK33197.1 - 0.021 15.1 0.0 0.15 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KIK33197.1 - 0.026 14.9 0.0 0.083 13.3 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK33197.1 - 0.075 13.4 0.0 0.23 11.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KIK33197.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 KIK33197.1 - 0.13 11.4 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase APS_kinase PF01583.20 KIK33197.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Glypican PF01153.19 KIK33198.1 - 0.37 9.6 0.4 0.41 9.4 0.4 1.1 1 0 0 1 1 1 0 Glypican WD40 PF00400.32 KIK33201.1 - 2e-06 28.4 0.9 0.091 13.7 0.2 2.4 2 1 0 2 2 2 2 WD domain, G-beta repeat DUF3861 PF12977.7 KIK33202.1 - 0.084 13.0 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3861) MutS_IV PF05190.18 KIK33202.1 - 0.15 12.4 4.2 2.8 8.3 0.3 2.7 3 0 0 3 3 3 0 MutS family domain IV CK_II_beta PF01214.18 KIK33203.1 - 4.5 7.0 6.4 8.8 6.1 6.4 1.4 1 0 0 1 1 1 0 Casein kinase II regulatory subunit FYVE_2 PF02318.16 KIK33203.1 - 5 7.4 7.6 18 5.6 6.6 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger Tet_JBP PF12851.7 KIK33205.1 - 0.00023 20.6 0.0 0.0016 17.9 0.0 1.9 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily CxC2 PF18803.1 KIK33206.1 - 1.2e-28 99.4 0.3 1.7e-27 95.7 0.3 2.3 1 1 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK33206.1 - 1.8e-06 28.0 0.0 3.8e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK33206.1 - 0.0011 18.7 0.1 0.0011 18.7 0.1 1.7 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 KIK33206.1 - 0.0063 16.6 3.2 0.017 15.3 3.2 1.7 1 0 0 1 1 1 1 B-box zinc finger KDZ PF18758.1 KIK33207.1 - 2.1e-49 168.2 0.1 4.5e-49 167.1 0.1 1.6 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Tropomyosin PF00261.20 KIK33207.1 - 0.43 9.9 2.9 1.3 8.4 0.0 2.4 3 0 0 3 3 3 0 Tropomyosin Retrotran_gag_2 PF14223.6 KIK33208.1 - 0.0016 18.1 0.3 0.0025 17.5 0.3 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type AA_permease_2 PF13520.6 KIK33211.1 - 7.2e-11 41.6 11.4 8.3e-11 41.4 11.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK33211.1 - 1e-05 24.4 9.2 1.2e-05 24.1 9.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK33212.1 - 1.4e-25 90.0 20.8 1.7e-25 89.7 20.8 1.0 1 0 0 1 1 1 1 Amino acid permease NlpE PF04170.12 KIK33213.1 - 0.067 14.2 0.4 0.084 13.8 0.4 1.2 1 0 0 1 1 1 0 NlpE N-terminal domain Retrotrans_gag PF03732.17 KIK33218.1 - 0.00093 19.4 3.9 0.068 13.5 0.3 2.6 3 0 0 3 3 3 2 Retrotransposon gag protein Peptidase_M3_N PF08439.10 KIK33218.1 - 0.035 14.4 0.5 0.1 12.9 0.3 1.8 2 0 0 2 2 2 0 Oligopeptidase F DUF987 PF06174.11 KIK33220.1 - 0.004 17.1 0.0 0.0061 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF987) HTH_Tnp_Tc5 PF03221.16 KIK33220.1 - 0.0055 16.7 0.0 0.0073 16.3 0.0 1.2 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain WD40 PF00400.32 KIK33225.1 - 7e-31 105.8 14.4 7e-06 26.7 0.0 8.4 8 0 0 8 8 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33225.1 - 2.3e-10 40.6 0.1 0.095 13.0 0.0 5.2 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 KIK33225.1 - 4e-10 40.2 3.2 7.6e-08 32.8 0.2 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) eIF2A PF08662.11 KIK33225.1 - 1.3e-07 31.7 0.0 0.0042 17.0 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK33225.1 - 0.00019 20.5 0.3 0.0006 18.9 0.0 2.0 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_2 PF07719.17 KIK33225.1 - 0.0017 18.3 10.0 0.88 9.8 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK33225.1 - 0.0025 17.6 7.8 0.69 9.8 0.1 5.0 6 0 0 6 6 5 2 Tetratricopeptide repeat Nbas_N PF15492.6 KIK33225.1 - 0.0098 15.2 0.2 0.51 9.6 0.0 3.3 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal TPR_7 PF13176.6 KIK33225.1 - 0.02 14.9 2.9 7.7 6.8 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK33225.1 - 0.021 14.5 0.3 0.55 10.0 0.1 2.6 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 KIK33225.1 - 0.026 15.3 11.1 5.3 8.1 0.1 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK33225.1 - 0.15 12.8 13.4 0.36 11.5 0.8 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Spo0A_C PF08769.11 KIK33225.1 - 0.17 12.0 0.0 0.47 10.6 0.0 1.7 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal TPR_19 PF14559.6 KIK33225.1 - 0.27 11.8 7.0 11 6.6 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 KIK33225.1 - 0.47 10.5 2.2 12 6.1 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.32 KIK33228.1 - 8.2e-19 67.6 8.6 1.8e-08 34.9 0.2 3.4 3 1 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33228.1 - 1.8e-06 28.1 0.1 0.0066 16.7 0.0 2.5 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK33228.1 - 0.001 17.8 0.3 0.24 10.0 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 MFMR PF07777.11 KIK33228.1 - 0.074 13.6 0.3 0.1 13.1 0.3 1.2 1 0 0 1 1 1 0 G-box binding protein MFMR SCAI PF12070.8 KIK33229.1 - 0.0071 15.3 0.1 0.0092 14.9 0.1 1.1 1 0 0 1 1 1 1 Protein SCAI Rrn6 PF10214.9 KIK33229.1 - 0.2 10.1 4.5 0.29 9.6 4.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Phage_integrase PF00589.22 KIK33231.1 - 4.5e-05 23.3 0.0 5.6e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 Phage integrase family KDZ PF18758.1 KIK33232.1 - 1.3e-78 263.7 0.2 2e-78 263.1 0.2 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK33232.1 - 2.9e-05 24.2 0.1 7.3e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK33232.1 - 0.0067 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases Ins_allergen_rp PF06757.13 KIK33232.1 - 0.076 13.0 0.9 0.53 10.2 0.0 2.4 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification HET PF06985.11 KIK33235.1 - 7.8e-11 42.5 2.6 8.4e-08 32.7 0.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) WD40 PF00400.32 KIK33236.1 - 9e-36 121.3 11.5 3.1e-06 27.8 0.0 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33236.1 - 1.7e-08 34.6 0.3 0.72 10.2 0.1 4.9 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 KIK33236.1 - 6.8e-08 33.0 2.3 7.5e-07 29.6 0.3 2.4 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Ge1_WD40 PF16529.5 KIK33236.1 - 0.00053 19.0 0.0 0.041 12.8 0.0 3.1 3 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK33236.1 - 0.072 11.7 1.7 5.2 5.6 0.0 2.4 2 1 0 2 2 2 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK33236.1 - 0.16 11.3 0.0 4.5 6.5 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain G-patch_2 PF12656.7 KIK33238.1 - 0.025 14.6 0.4 0.036 14.2 0.4 1.2 1 0 0 1 1 1 0 G-patch domain Nodulin_late PF07127.11 KIK33239.1 - 0.016 15.6 1.1 0.032 14.6 1.1 1.4 1 0 0 1 1 1 0 Late nodulin protein Toxin_20 PF08089.11 KIK33239.1 - 0.098 12.8 1.2 0.19 11.9 1.2 1.4 1 0 0 1 1 1 0 Huwentoxin-II family LRR_8 PF13855.6 KIK33240.1 - 1.1 9.1 3.4 2.4 8.0 0.7 2.8 2 1 1 3 3 3 0 Leucine rich repeat Phosducin PF02114.16 KIK33241.1 - 2.2e-15 56.3 0.0 2.5e-07 29.9 0.0 3.1 2 1 1 3 3 3 3 Phosducin Trehalase PF01204.18 KIK33242.1 - 3.1e-166 554.2 0.0 3.8e-166 553.9 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KIK33242.1 - 7.6e-15 54.3 0.1 1.4e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Lipase_3 PF01764.25 KIK33243.1 - 3.8e-06 26.8 0.0 2.5e-05 24.2 0.0 2.0 1 1 1 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIK33243.1 - 0.011 16.4 0.1 0.018 15.6 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KIK33243.1 - 0.033 13.9 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase PF00151.19 KIK33243.1 - 0.21 10.8 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Lipase Metallothio_11 PF02066.15 KIK33243.1 - 0.36 11.0 3.7 0.85 9.9 3.7 1.7 1 0 0 1 1 1 0 Metallothionein family 11 Pkinase_fungal PF17667.1 KIK33246.1 - 9.1e-41 140.0 0.0 3.7e-25 88.5 0.0 2.0 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIK33246.1 - 0.00044 19.7 0.0 0.0029 17.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain GPS2_interact PF15784.5 KIK33247.1 - 0.0035 17.7 0.5 0.0058 17.0 0.5 1.3 1 0 0 1 1 1 1 G-protein pathway suppressor 2-interacting domain Ran-binding PF05508.11 KIK33247.1 - 0.011 14.7 0.1 0.013 14.5 0.1 1.0 1 0 0 1 1 1 0 RanGTP-binding protein SAB PF04382.13 KIK33247.1 - 0.054 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 SAB domain ZapB PF06005.12 KIK33247.1 - 0.056 13.9 0.8 0.094 13.2 0.8 1.3 1 0 0 1 1 1 0 Cell division protein ZapB DUF5615 PF18480.1 KIK33247.1 - 0.067 13.0 0.0 0.091 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) Pkinase_fungal PF17667.1 KIK33249.1 - 6.2e-18 64.8 0.0 9.5e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK33249.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KIK33249.1 - 0.065 12.6 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain Pkinase_fungal PF17667.1 KIK33251.1 - 1.7e-13 50.1 0.0 1.9e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase TPR_10 PF13374.6 KIK33252.1 - 2.4e-05 24.0 4.8 0.12 12.3 0.6 3.8 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK33252.1 - 0.0012 19.0 1.4 0.42 10.9 0.7 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK33252.1 - 0.0084 16.4 0.3 0.23 11.9 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK33252.1 - 0.013 16.2 3.3 3.2 8.8 0.4 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK33252.1 - 1.3 9.2 4.7 9.4 6.5 0.4 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 KIK33253.1 - 1.6e-37 129.2 0.0 1.8e-37 129.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK33253.1 - 5e-33 114.6 0.0 6.4e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KIK33253.1 - 9.9e-05 21.8 0.0 0.00012 21.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIK33253.1 - 0.00018 21.5 0.0 0.00037 20.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KIK33253.1 - 0.0074 15.7 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KIK33253.1 - 0.013 14.5 0.1 0.024 13.7 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 CHAT PF12770.7 KIK33260.1 - 6.5e-33 114.4 0.0 1.6e-32 113.1 0.0 1.6 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK33260.1 - 1.2e-15 56.7 10.3 0.17 11.8 0.0 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 KIK33260.1 - 3.5e-07 30.4 18.2 0.034 14.4 0.2 7.9 5 3 3 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 KIK33260.1 - 0.00011 22.1 0.5 10 6.6 0.0 6.2 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK33260.1 - 0.00014 21.7 5.5 9.7 6.6 0.0 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK33260.1 - 0.002 17.8 0.7 30 4.4 0.0 5.3 6 0 0 6 6 6 0 TPR repeat Zeta_toxin PF06414.12 KIK33260.1 - 0.0095 15.2 0.0 0.025 13.9 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin Dehydratase_SU PF02287.15 KIK33260.1 - 0.016 15.3 0.3 3.2 7.8 0.0 2.8 2 0 0 2 2 2 0 Dehydratase small subunit TPR_7 PF13176.6 KIK33260.1 - 0.038 14.0 9.9 31 4.9 0.0 6.7 6 2 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 KIK33260.1 - 0.13 12.4 0.6 39 4.4 0.0 4.6 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 KIK33260.1 - 0.14 12.1 6.0 19 5.2 0.0 6.0 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK33260.1 - 0.25 12.3 24.6 23 6.1 0.0 9.7 11 1 1 12 12 10 0 Tetratricopeptide repeat Vta1_C PF18097.1 KIK33260.1 - 1.8 8.3 11.1 8.1 6.2 0.5 5.1 4 0 0 4 4 4 0 Vta1 C-terminal domain WD40 PF00400.32 KIK33261.1 - 8.6e-34 115.0 12.1 4.1e-06 27.4 1.8 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33261.1 - 3.5e-17 62.5 1.5 6.1e-05 23.2 0.0 5.0 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK33261.1 - 8.3e-07 28.3 0.1 0.054 12.4 0.0 3.8 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK33261.1 - 1.4e-06 28.3 0.2 3.1e-05 23.9 0.1 2.6 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK33261.1 - 0.00034 19.4 4.0 0.39 9.3 0.2 4.1 3 1 1 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK33261.1 - 0.00055 19.4 0.0 0.3 10.4 0.0 2.9 2 1 1 3 3 3 1 WD40-like domain Nbas_N PF15492.6 KIK33261.1 - 0.0035 16.7 0.2 1.7 7.9 0.0 3.3 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal BAH PF01426.18 KIK33261.1 - 0.0061 16.4 0.0 0.0098 15.7 0.0 1.3 1 0 0 1 1 1 1 BAH domain Arena_nucleocap PF00843.17 KIK33261.1 - 0.099 11.5 1.5 5 5.9 0.2 2.2 1 1 1 2 2 2 0 Arenavirus nucleocapsid N-terminal domain Hira PF07569.11 KIK33261.1 - 0.44 10.2 3.7 18 4.9 0.0 3.5 1 1 3 4 4 4 0 TUP1-like enhancer of split WD40 PF00400.32 KIK33262.1 - 5.6e-42 140.9 11.7 2.5e-06 28.1 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33262.1 - 2.6e-18 66.1 4.6 0.00065 20.0 0.1 6.0 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK33262.1 - 1e-08 34.6 0.1 0.003 16.6 0.0 3.9 2 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK33262.1 - 1.1e-07 30.9 1.2 0.53 8.9 0.0 4.1 1 1 1 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK33262.1 - 7.5e-06 26.0 0.6 0.17 11.8 0.0 3.5 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KIK33262.1 - 8.9e-05 21.9 0.1 0.027 13.8 0.0 3.4 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK33262.1 - 0.0004 19.8 0.0 0.042 13.2 0.0 3.1 1 1 3 4 4 4 1 WD40-like domain PD40 PF07676.12 KIK33262.1 - 0.0084 16.0 0.0 4.1 7.5 0.0 3.7 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK33262.1 - 0.047 12.0 0.0 2.2 6.5 0.0 2.6 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 KIK33262.1 - 0.047 14.2 0.9 3.2 8.4 0.0 3.6 3 1 0 3 3 3 0 PQQ-like domain Me-amine-dh_H PF06433.11 KIK33262.1 - 0.059 12.2 0.0 2.3 7.0 0.0 2.4 2 1 1 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) DPPIV_N PF00930.21 KIK33262.1 - 0.088 11.6 0.6 3 6.5 0.0 3.0 1 1 2 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Cauli_VI PF01693.16 KIK33265.1 - 3.6e-05 24.0 0.1 4.5e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Caulimovirus viroplasmin TMF_TATA_bd PF12325.8 KIK33266.1 - 0.088 13.0 1.4 0.17 12.1 1.4 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding AAA_11 PF13086.6 KIK33266.1 - 0.14 11.9 1.7 0.19 11.5 1.7 1.1 1 0 0 1 1 1 0 AAA domain HTH_32 PF13565.6 KIK33268.1 - 2.1e-08 34.6 0.3 1.1e-05 25.9 0.0 3.0 2 2 1 3 3 3 2 Homeodomain-like domain HTH_23 PF13384.6 KIK33268.1 - 1.1e-06 28.3 0.9 7.7e-05 22.4 0.0 3.2 4 0 0 4 4 4 1 Homeodomain-like domain HTH_33 PF13592.6 KIK33268.1 - 1.3e-05 24.8 0.0 4.1e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.15 KIK33268.1 - 0.0008 19.4 1.2 1.4 9.1 0.0 3.6 4 1 1 5 5 5 2 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 KIK33268.1 - 0.0023 18.0 1.0 0.043 13.9 0.0 3.1 3 1 0 3 3 3 1 Helix-turn-helix domain HTH_29 PF13551.6 KIK33268.1 - 0.0029 17.6 0.2 0.024 14.7 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn helix UPF0175 PF03683.13 KIK33268.1 - 0.013 15.2 0.0 0.05 13.3 0.0 2.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) HTH_AraC PF00165.23 KIK33268.1 - 0.015 15.4 0.0 0.14 12.3 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_Tnp_Tc3_2 PF01498.18 KIK33268.1 - 0.03 14.6 0.0 0.08 13.2 0.0 1.8 1 0 0 1 1 1 0 Transposase HTH_38 PF13936.6 KIK33268.1 - 0.07 12.9 2.1 0.9 9.4 0.1 3.7 4 1 1 5 5 5 0 Helix-turn-helix domain CPSase_L_D3 PF02787.19 KIK33268.1 - 0.13 12.6 0.1 0.22 11.9 0.1 1.5 1 1 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain F-box-like PF12937.7 KIK33273.1 - 9e-09 35.1 1.1 1.3e-08 34.6 1.1 1.2 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KIK33273.1 - 0.0041 17.1 0.1 0.0054 16.7 0.0 1.2 1 1 0 1 1 1 1 F-box-like domain SPATA3 PF15662.5 KIK33273.1 - 0.052 14.2 0.1 0.06 14.0 0.1 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family zf-H2C2_5 PF13909.6 KIK33274.1 - 2.7e-09 36.6 10.2 0.00012 21.7 0.4 3.4 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIK33274.1 - 1.3e-08 34.8 14.7 0.02 15.3 1.2 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK33274.1 - 6.5e-06 26.3 13.9 0.00032 21.0 0.4 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK33274.1 - 0.00047 20.8 13.9 0.53 11.3 1.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK33274.1 - 0.56 10.6 4.5 1.9 8.9 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding OrsD PF12013.8 KIK33274.1 - 5 7.6 8.6 11 6.5 0.2 3.1 1 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D Pro_3_hydrox_C PF05373.11 KIK33276.1 - 0.074 13.1 0.0 0.09 12.9 0.0 1.1 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal Dimer_Tnp_hAT PF05699.14 KIK33277.1 - 6.7e-14 51.5 0.0 7e-14 51.4 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF1323 PF07037.11 KIK33278.1 - 0.2 12.1 0.0 0.29 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative transcription regulator (DUF1323) Retrotrans_gag PF03732.17 KIK33281.1 - 4.4e-06 26.9 0.2 7.9e-06 26.1 0.2 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 KIK33281.1 - 0.00025 21.0 5.3 0.00049 20.0 5.3 1.5 1 0 0 1 1 1 1 Zinc knuckle CDC45 PF02724.14 KIK33281.1 - 0.063 11.6 9.7 0.026 12.9 3.0 2.0 2 0 0 2 2 2 0 CDC45-like protein zf-CCHC_2 PF13696.6 KIK33281.1 - 0.3 10.9 5.8 0.66 9.8 5.8 1.6 1 0 0 1 1 1 0 Zinc knuckle Coilin_N PF15862.5 KIK33281.1 - 3.7 7.4 13.8 11 5.8 6.6 2.3 2 0 0 2 2 2 0 Coilin N-terminus DUF4598 PF15370.6 KIK33281.1 - 5.2 7.6 10.2 3.1 8.3 4.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) Pol_alpha_B_N PF08418.10 KIK33284.1 - 0.53 10.2 6.9 0.85 9.5 6.9 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal ATF7IP_BD PF16788.5 KIK33284.1 - 5.3 7.1 10.3 10 6.2 10.3 1.4 1 0 0 1 1 1 0 ATF-interacting protein binding domain MAP65_ASE1 PF03999.12 KIK33284.1 - 6.7 5.3 9.2 8.6 4.9 9.2 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) KDZ PF18758.1 KIK33285.1 - 1e-78 264.0 0.2 1.7e-78 263.3 0.2 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK33285.1 - 0.00078 19.6 0.0 0.0022 18.1 0.0 1.8 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Spem1 PF15670.5 KIK33286.1 - 2 7.9 6.5 4.5 6.8 6.5 1.5 1 0 0 1 1 1 0 Spermatid maturation protein 1 HCMVantigenic_N PF12154.8 KIK33286.1 - 6.5 7.0 5.7 0.71 10.0 0.6 2.0 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV BID PF06393.11 KIK33287.1 - 0.029 13.9 0.3 0.043 13.3 0.3 1.3 1 0 0 1 1 1 0 BH3 interacting domain (BID) Dpoe2NT PF12213.8 KIK33289.1 - 0.043 14.1 0.6 0.1 12.9 0.1 1.8 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal Fer4 PF00037.27 KIK33293.1 - 0.0048 16.6 7.9 0.69 9.8 0.4 3.0 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KIK33293.1 - 2.8 8.6 22.6 0.043 14.4 13.2 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain SGL PF08450.12 KIK33294.1 - 3.6e-22 79.1 0.0 7.2e-22 78.2 0.0 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KIK33294.1 - 1.7e-05 24.8 0.0 8.4e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 KIK33294.1 - 0.00084 19.5 0.1 0.0039 17.3 0.0 2.2 2 0 0 2 2 2 1 Arylesterase Pkinase PF00069.25 KIK33295.1 - 0.00014 21.4 0.0 0.00015 21.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain SGL PF08450.12 KIK33296.1 - 7.1e-23 81.4 0.0 2.3e-22 79.8 0.0 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KIK33296.1 - 9.4e-07 28.9 0.0 1.8e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.20 KIK33296.1 - 2.5e-05 24.4 0.0 9.4e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Arylesterase Kelch_4 PF13418.6 KIK33296.1 - 0.059 13.4 0.1 8.2 6.5 0.0 3.1 3 0 0 3 3 3 0 Galactose oxidase, central domain CHAT PF12770.7 KIK33299.1 - 2.5e-29 102.6 0.0 4.7e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK33299.1 - 5.5e-12 45.1 6.5 0.081 12.8 0.1 8.2 6 2 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK33299.1 - 7.7e-12 45.3 6.5 0.011 16.0 0.1 8.1 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK33299.1 - 3.9e-09 35.9 6.4 2.6 8.4 0.0 7.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 KIK33299.1 - 7.4e-08 31.9 9.1 0.14 12.0 0.0 6.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK33299.1 - 3.7e-07 29.7 0.2 25 5.2 0.0 6.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK33299.1 - 3.1e-06 27.0 0.1 17 6.0 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK33299.1 - 0.00016 21.3 0.0 2.4 7.9 0.0 4.1 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.6 KIK33299.1 - 0.00053 20.6 20.3 9.9 7.3 0.0 9.8 10 2 2 12 12 11 1 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 KIK33299.1 - 0.12 12.4 0.1 4.2 7.5 0.0 3.5 3 0 0 3 3 3 0 Exonuclease VII small subunit Zeta_toxin PF06414.12 KIK33299.1 - 0.13 11.5 0.1 0.44 9.8 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Vta1_C PF18097.1 KIK33299.1 - 1.1 9.0 5.7 1.4 8.7 0.1 3.7 3 0 0 3 3 3 0 Vta1 C-terminal domain KDZ PF18758.1 KIK33301.1 - 3.7e-85 285.1 0.2 5.7e-85 284.5 0.2 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK33301.1 - 0.0031 17.7 0.0 0.0072 16.5 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases DUF3106 PF11304.8 KIK33303.1 - 4.4 7.8 8.3 1.3 9.5 0.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) Pkinase PF00069.25 KIK33305.1 - 5e-33 114.6 0.0 6.4e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK33305.1 - 2.2e-13 50.1 0.0 2.6e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIK33305.1 - 0.0015 17.9 0.1 0.0021 17.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIK33305.1 - 0.0024 17.3 0.0 0.0045 16.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIK33305.1 - 0.0035 16.2 0.0 0.0047 15.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK33305.1 - 0.021 14.8 0.2 0.059 13.3 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK33305.1 - 0.042 12.8 0.1 0.06 12.3 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Zn_clus PF00172.18 KIK33307.1 - 2.8e-09 37.0 8.3 5.1e-09 36.1 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIK33307.1 - 2.7e-07 29.9 0.0 6.1e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain KAR9 PF08580.10 KIK33309.1 - 0.13 10.8 4.1 0.16 10.5 4.1 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 zf-Di19 PF05605.12 KIK33311.1 - 0.023 15.0 0.7 0.023 15.0 0.7 1.8 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding KNOX2 PF03791.13 KIK33311.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 KNOX2 domain FOXP-CC PF16159.5 KIK33311.1 - 2.5 8.8 5.9 0.15 12.7 1.1 1.5 2 0 0 2 2 2 0 FOXP coiled-coil domain FHA PF00498.26 KIK33313.1 - 5.3e-18 65.1 0.3 1.7e-17 63.5 0.1 2.1 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KIK33313.1 - 0.00099 19.4 0.0 0.0034 17.7 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain JHY PF15261.6 KIK33313.1 - 0.07 13.8 0.2 0.07 13.8 0.2 2.6 2 1 0 2 2 2 0 Jhy protein DUF1664 PF07889.12 KIK33313.1 - 0.072 13.1 5.5 2.7 8.0 0.2 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KIK33313.1 - 0.082 13.4 7.6 14 6.3 0.0 4.3 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein CoatB PF10389.9 KIK33313.1 - 0.17 11.7 2.1 0.44 10.4 2.1 1.6 1 0 0 1 1 1 0 Bacteriophage coat protein B DUF1640 PF07798.11 KIK33313.1 - 0.49 10.4 7.0 0.48 10.5 1.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Nucleo_P87 PF07267.11 KIK33313.1 - 2.6 6.8 8.7 0.83 8.4 5.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 GST_N_3 PF13417.6 KIK33316.1 - 0.00075 19.9 0.0 0.00093 19.6 0.0 1.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK33316.1 - 0.0011 19.2 0.0 0.0021 18.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK33316.1 - 0.0029 17.9 0.0 0.0037 17.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain zf-C3HC4_3 PF13920.6 KIK33317.1 - 0.025 14.4 1.7 2.2 8.2 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK33317.1 - 0.18 11.7 1.9 2.2 8.2 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C6H2 PF15801.5 KIK33317.1 - 0.35 11.2 1.6 3 8.2 0.1 2.3 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding PIF1 PF05970.14 KIK33322.1 - 5.2e-12 45.6 0.4 0.0001 21.6 0.1 3.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KIK33322.1 - 3.1e-06 27.0 0.9 0.038 13.7 0.9 3.0 1 1 1 2 2 2 2 AAA domain SH3_13 PF18335.1 KIK33322.1 - 0.017 14.9 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain AAA_19 PF13245.6 KIK33322.1 - 0.038 14.3 1.9 0.42 11.0 0.7 2.4 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 KIK33322.1 - 0.13 12.6 0.1 0.39 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KIK33322.1 - 0.14 12.4 0.1 0.45 10.8 0.1 1.8 1 0 0 1 1 1 0 AAA domain Helitron_like_N PF14214.6 KIK33323.1 - 1.6e-30 106.7 0.0 3.5e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus MPLKIP PF15502.6 KIK33323.1 - 0.15 12.3 0.2 0.43 10.8 0.2 1.8 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein Acetyltransf_3 PF13302.7 KIK33326.1 - 3e-14 53.9 0.0 3.8e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK33326.1 - 6e-05 23.3 0.0 0.00038 20.7 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Pkr1 PF08636.10 KIK33327.1 - 0.33 11.1 3.2 0.21 11.8 1.1 1.7 2 0 0 2 2 2 0 ER protein Pkr1 WD40 PF00400.32 KIK33328.1 - 2.4e-29 101.0 11.0 2.2e-07 31.5 0.1 5.0 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33328.1 - 1.8e-12 47.4 1.3 0.0031 17.8 0.1 4.2 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK33328.1 - 0.0013 17.8 0.0 1.3 7.9 0.0 3.7 1 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK33328.1 - 0.0017 18.2 0.0 15 5.7 0.0 4.7 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KIK33328.1 - 0.0023 16.5 0.0 0.41 9.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 KIK33328.1 - 0.0071 15.1 1.1 0.28 9.8 0.1 2.2 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Gmad1 PF10647.9 KIK33328.1 - 0.04 13.7 0.5 3 7.5 0.1 2.8 2 2 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain Myb_DNA-bind_3 PF12776.7 KIK33329.1 - 0.06 14.3 0.0 0.073 14.1 0.0 1.1 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain WD40 PF00400.32 KIK33335.1 - 1.6e-26 92.1 3.4 5.2e-08 33.4 0.3 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33335.1 - 3.5e-10 40.0 0.0 0.018 15.3 0.1 3.5 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK33335.1 - 5.6e-05 22.0 0.5 0.022 13.4 0.1 3.1 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK33335.1 - 0.0012 17.9 0.1 0.94 8.4 0.1 2.3 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CENP-R PF06729.12 KIK33338.1 - 0.89 9.5 3.7 1.7 8.6 3.7 1.4 1 0 0 1 1 1 0 Kinetochore component, CENP-R SesA PF17107.5 KIK33340.1 - 0.024 14.8 0.8 0.2 11.9 0.1 2.7 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases KDZ PF18758.1 KIK33342.1 - 9.9e-78 260.8 0.0 2.2e-77 259.6 0.0 1.6 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Lipoprotein_8 PF02030.15 KIK33342.1 - 0.065 12.0 4.1 0.45 9.2 4.0 1.9 1 1 0 1 1 1 0 Hypothetical lipoprotein (MG045 family) NopRA1 PF16201.5 KIK33345.1 - 0.0011 18.6 0.1 0.0015 18.2 0.1 1.2 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Arm PF00514.23 KIK33345.1 - 0.051 13.6 0.0 0.08 13.0 0.0 1.3 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Terminase_4 PF05119.12 KIK33347.1 - 0.12 12.8 0.1 0.14 12.6 0.1 1.2 1 0 0 1 1 1 0 Phage terminase, small subunit AP_endonuc_2_N PF07582.12 KIK33348.1 - 0.1 12.3 0.0 0.35 10.6 0.0 1.8 1 1 1 2 2 2 0 AP endonuclease family 2 C terminus AAA_16 PF13191.6 KIK33349.1 - 1.1e-09 38.8 0.0 2.3e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK33349.1 - 1e-05 25.5 0.0 2.2e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA PF00004.29 KIK33349.1 - 0.00029 21.3 0.0 0.0011 19.5 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KIK33349.1 - 0.0005 20.1 0.0 0.0013 18.7 0.0 1.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KIK33349.1 - 0.0038 17.6 0.0 0.013 15.9 0.0 1.9 1 0 0 1 1 1 1 RNA helicase APS_kinase PF01583.20 KIK33349.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_PrkA PF08298.11 KIK33349.1 - 0.02 13.8 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain NB-ARC PF00931.22 KIK33349.1 - 0.025 13.7 0.1 0.17 11.0 0.0 2.2 2 1 0 2 2 2 0 NB-ARC domain Parvo_NS1 PF01057.17 KIK33349.1 - 0.084 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Retrotrans_gag PF03732.17 KIK33350.1 - 4.6e-08 33.2 0.2 7.9e-08 32.5 0.2 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 KIK33350.1 - 9e-05 22.4 1.9 0.0002 21.3 1.9 1.6 1 0 0 1 1 1 1 Zinc knuckle SR-25 PF10500.9 KIK33350.1 - 0.014 15.0 19.0 0.014 15.0 19.0 2.5 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein SpoIIIAH PF12685.7 KIK33350.1 - 0.023 14.5 1.6 0.043 13.6 1.6 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein SPX PF03105.19 KIK33350.1 - 0.39 10.6 17.8 0.048 13.6 3.4 2.1 2 0 0 2 2 2 0 SPX domain Rhodanese_C PF12368.8 KIK33350.1 - 0.4 11.1 1.9 4.9 7.6 0.2 2.7 2 1 0 2 2 2 0 Rhodanase C-terminal gag-asp_proteas PF13975.6 KIK33352.1 - 3.3e-07 30.8 0.0 7.6e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KIK33352.1 - 7.4e-07 29.0 0.0 8.3e-05 22.4 0.0 2.2 1 1 1 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KIK33352.1 - 1.2e-06 29.0 0.0 2.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KIK33352.1 - 9.7e-05 22.2 0.0 0.019 14.8 0.0 2.3 1 1 1 2 2 2 2 Aspartyl protease PfUIS3 PF11567.8 KIK33354.1 - 0.21 12.0 1.8 0.67 10.3 1.8 1.8 1 0 0 1 1 1 0 Plasmodium falciparum UIS3 membrane protein CitG PF01874.16 KIK33354.1 - 0.29 10.7 2.8 17 5.0 0.0 2.4 2 0 0 2 2 2 0 ATP:dephospho-CoA triphosphoribosyl transferase Prominin PF05478.11 KIK33354.1 - 4.3 5.2 7.0 6.4 4.6 7.0 1.2 1 0 0 1 1 1 0 Prominin MAGE PF01454.19 KIK33355.1 - 0.047 13.4 0.2 0.073 12.8 0.2 1.3 1 0 0 1 1 1 0 MAGE family DSPc PF00782.20 KIK33359.1 - 4.4e-05 23.3 0.0 0.00013 21.8 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 KIK33359.1 - 0.018 14.7 0.1 0.03 14.0 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 KIK33359.1 - 0.11 12.7 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 KIK33359.1 - 0.24 10.9 0.3 0.85 9.1 0.0 1.8 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Chromo PF00385.24 KIK33360.1 - 0.021 14.7 0.1 0.029 14.3 0.1 1.2 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Chitin_synth_2 PF03142.15 KIK33361.1 - 1.2e-252 839.2 0.2 1.6e-252 838.8 0.2 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 KIK33361.1 - 7.3e-15 55.5 0.1 1.5e-13 51.2 0.1 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KIK33361.1 - 7.4e-12 45.6 9.3 7.4e-12 45.6 9.3 2.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KIK33361.1 - 0.001 18.6 0.1 0.11 12.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KIK33361.1 - 0.073 12.9 0.0 2.5 7.9 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 CHAT PF12770.7 KIK33364.1 - 8.3e-43 146.8 0.0 1.9e-42 145.7 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK33364.1 - 2e-09 37.0 2.8 0.0087 15.9 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK33364.1 - 0.00021 21.1 0.1 1.3 9.2 0.0 3.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK33364.1 - 0.0024 18.1 5.8 8.4 6.8 0.2 4.7 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK33364.1 - 0.1 13.5 5.1 56 4.9 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3305 PF11749.8 KIK33365.1 - 0.13 12.3 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3305) Oxidored_FMN PF00724.20 KIK33369.1 - 1.2e-97 327.3 0.0 1.4e-97 327.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.21 KIK33369.1 - 0.053 13.5 0.0 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 Tautomerase enzyme DUF2863 PF11062.8 KIK33371.1 - 0.091 11.2 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) Pkinase_fungal PF17667.1 KIK33372.1 - 1.5e-20 73.4 0.1 1.2e-12 47.3 0.1 2.1 2 0 0 2 2 2 2 Fungal protein kinase Cpn60_TCP1 PF00118.24 KIK33373.1 - 2.5e-145 484.9 15.7 2.9e-145 484.7 15.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 KIK33373.1 - 0.07 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat DUF2711 PF10924.8 KIK33373.1 - 0.13 11.8 0.1 0.31 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) Pkinase_fungal PF17667.1 KIK33374.1 - 1.5e-05 24.0 0.3 2.3e-05 23.4 0.3 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 KIK33375.1 - 4.1e-16 58.8 0.0 5.3e-12 45.2 0.0 2.2 1 1 1 2 2 2 2 Fungal protein kinase NolV PF06635.12 KIK33375.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein NolV LON_substr_bdg PF02190.16 KIK33377.1 - 0.088 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain Plavaka PF18759.1 KIK33378.1 - 1.1e-114 383.1 0.0 1.6e-114 382.5 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase zf-met PF12874.7 KIK33378.1 - 0.045 14.1 0.1 0.22 12.0 0.1 2.2 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Ribosomal_S5 PF00333.20 KIK33380.1 - 0.18 11.8 1.1 2.6 8.1 0.0 2.5 3 0 0 3 3 3 0 Ribosomal protein S5, N-terminal domain zf-DNL PF05180.12 KIK33381.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 DNL zinc finger HET PF06985.11 KIK33382.1 - 2.4e-09 37.7 7.9 3.2e-09 37.3 2.1 2.9 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) F-box-like PF12937.7 KIK33388.1 - 3.9e-05 23.4 5.0 0.00023 21.0 4.0 2.8 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIK33388.1 - 0.0064 16.9 2.6 0.027 14.9 0.0 3.3 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) HIT PF01230.23 KIK33389.1 - 6.2e-25 87.8 0.1 9e-25 87.3 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KIK33389.1 - 1.6e-10 41.5 0.1 2.2e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KIK33389.1 - 3.8e-06 26.8 0.0 1.1e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 Ras PF00071.22 KIK33390.1 - 4.4e-16 58.9 0.0 5.8e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Pyr_redox_2 PF07992.14 KIK33391.1 - 7e-52 176.5 0.0 8.2e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK33391.1 - 3.2e-18 66.1 0.3 3.7e-15 56.2 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK33391.1 - 3.4e-16 59.4 0.1 1.4e-12 47.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK33391.1 - 1.2e-06 27.9 0.0 3.7e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KIK33391.1 - 4.5e-05 23.6 0.5 0.0033 17.6 0.0 2.6 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK33391.1 - 9.9e-05 22.1 1.1 0.0024 17.5 0.1 2.8 1 1 1 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 KIK33391.1 - 0.00015 21.0 5.2 0.01 15.0 0.1 3.8 4 1 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KIK33391.1 - 0.00018 20.7 1.6 0.006 15.7 0.1 2.5 2 1 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KIK33391.1 - 0.00029 20.3 0.0 0.0066 15.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIK33391.1 - 0.0014 17.9 0.2 0.033 13.5 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 KIK33391.1 - 0.0016 18.5 0.3 3.2 7.8 0.0 3.2 3 1 1 4 4 4 2 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KIK33391.1 - 0.0022 18.4 0.0 0.14 12.6 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding Trp_halogenase PF04820.14 KIK33391.1 - 0.0063 15.4 0.0 0.068 12.0 0.0 2.4 3 0 0 3 3 3 1 Tryptophan halogenase K_oxygenase PF13434.6 KIK33391.1 - 0.011 14.9 0.0 1.6 7.7 0.0 3.3 3 1 1 4 4 4 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KIK33391.1 - 0.015 14.0 1.6 0.095 11.4 0.4 2.6 3 0 0 3 3 3 0 HI0933-like protein F420_oxidored PF03807.17 KIK33391.1 - 0.025 15.2 0.0 1.3 9.7 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KIK33391.1 - 0.071 12.8 0.8 12 5.5 0.1 2.6 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA HpaB PF03241.13 KIK33392.1 - 0.11 11.6 0.0 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal WD40 PF00400.32 KIK33394.1 - 1.6e-26 92.0 21.7 1.5e-06 28.8 0.7 5.4 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33394.1 - 3.9e-11 43.1 1.5 0.0006 20.1 0.2 4.3 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK33394.1 - 4.3e-05 22.6 0.0 0.14 11.1 0.0 3.5 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK33394.1 - 0.00014 21.9 0.0 0.12 12.2 0.0 2.6 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK33394.1 - 0.0018 17.0 0.3 1 7.9 0.1 2.7 3 0 0 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK33394.1 - 0.0031 16.9 0.0 0.018 14.4 0.0 2.0 2 1 1 3 3 3 1 WD40-like domain Nbas_N PF15492.6 KIK33394.1 - 0.006 16.0 0.2 0.047 13.0 0.1 2.2 1 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 KIK33394.1 - 0.016 14.1 3.1 0.15 11.0 0.0 2.7 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Cytochrom_D1 PF02239.16 KIK33394.1 - 0.02 13.4 0.0 0.093 11.2 0.1 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain WD40 PF00400.32 KIK33397.1 - 8.2e-44 146.7 27.3 1.8e-08 34.9 0.8 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33397.1 - 6.2e-21 74.5 5.0 0.00022 21.5 0.0 5.3 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK33397.1 - 4e-08 32.6 0.2 0.31 10.0 0.0 5.3 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KIK33397.1 - 3.5e-06 26.0 0.4 0.021 13.6 0.0 3.6 2 2 2 4 4 4 2 Nup133 N terminal like Nup160 PF11715.8 KIK33397.1 - 6e-06 25.2 3.9 0.54 8.8 0.0 4.8 2 1 3 5 5 5 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK33397.1 - 3.9e-05 23.6 0.7 0.0028 17.5 0.0 3.0 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KIK33397.1 - 0.00085 18.7 1.9 0.092 12.1 0.2 3.7 2 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK33397.1 - 0.0091 15.4 0.0 0.27 10.5 0.0 2.8 3 0 0 3 3 3 1 WD40-like domain PD40 PF07676.12 KIK33397.1 - 0.011 15.7 0.0 43 4.2 0.0 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK33397.1 - 0.13 10.5 0.0 1.9 6.7 0.0 2.4 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz RestrictionSfiI PF11487.8 KIK33403.1 - 0.12 12.2 0.3 11 5.8 0.0 2.1 2 0 0 2 2 2 0 Type II restriction enzyme SfiI HSP20 PF00011.21 KIK33413.1 - 1.8e-24 85.8 0.3 3.6e-24 84.9 0.2 1.4 1 1 1 2 2 2 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIK33413.1 - 5.2e-11 41.9 0.0 9e-11 41.2 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF4097 PF13349.6 KIK33413.1 - 0.0018 17.7 0.6 0.0022 17.4 0.6 1.1 1 0 0 1 1 1 1 Putative adhesin CS PF04969.16 KIK33413.1 - 0.02 15.9 0.1 0.048 14.7 0.1 1.7 1 1 0 1 1 1 0 CS domain FKBP26_C PF18046.1 KIK33413.1 - 0.036 14.2 0.1 12 6.1 0.0 2.3 2 0 0 2 2 2 0 FKBP26_C-terminal BON PF04972.17 KIK33413.1 - 0.085 13.2 0.4 0.51 10.7 0.1 2.0 2 0 0 2 2 2 0 BON domain DUF1735 PF08522.10 KIK33413.1 - 0.13 12.9 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1735) F-box-like PF12937.7 KIK33415.1 - 1.2e-09 37.9 2.9 2.9e-09 36.7 2.9 1.7 1 0 0 1 1 1 1 F-box-like PhzC-PhzF PF02567.16 KIK33416.1 - 1.5e-13 50.9 0.0 1.8e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Proteasome_A_N PF10584.9 KIK33416.1 - 0.029 14.0 0.1 0.073 12.8 0.0 1.8 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature CHAT PF12770.7 KIK33417.1 - 3.2e-41 141.6 0.0 6.4e-41 140.7 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK33417.1 - 7.1e-10 38.4 18.1 0.0033 17.2 0.4 6.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK33417.1 - 2e-07 31.2 11.7 0.13 12.6 0.2 6.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK33417.1 - 7.4e-05 22.4 4.2 0.42 10.5 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK33417.1 - 0.00032 20.3 0.5 2.7 7.7 0.0 4.3 4 0 0 4 4 4 1 TPR repeat TPR_7 PF13176.6 KIK33417.1 - 0.00075 19.4 6.2 10 6.4 0.1 5.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK33417.1 - 0.0086 16.8 12.4 7.8 7.6 0.0 6.2 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK33417.1 - 0.25 11.5 6.9 1.1 9.5 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2121 PF09894.9 KIK33422.1 - 0.097 12.2 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) WD40 PF00400.32 KIK33423.1 - 3.9e-41 138.3 10.5 2.1e-07 31.5 0.4 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33423.1 - 1.3e-09 38.2 0.5 0.22 11.9 0.0 5.4 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK33423.1 - 2.3e-05 23.5 0.5 0.59 9.0 0.0 4.1 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK33423.1 - 0.0048 15.6 0.1 0.091 11.4 0.0 2.7 3 0 0 3 3 3 1 Nucleoporin Nup120/160 PD40 PF07676.12 KIK33423.1 - 0.015 15.3 0.6 3.1 7.9 0.0 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PQQ PF01011.21 KIK33423.1 - 0.02 14.8 1.7 14 5.8 0.0 4.3 5 0 0 5 5 5 0 PQQ enzyme repeat GSDH PF07995.11 KIK33423.1 - 0.049 12.9 0.0 0.4 9.9 0.0 2.3 2 1 0 2 2 2 0 Glucose / Sorbosone dehydrogenase PALB2_WD40 PF16756.5 KIK33423.1 - 0.12 11.2 0.0 6.6 5.6 0.0 2.7 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain WD40 PF00400.32 KIK33425.1 - 2.9e-40 135.5 2.6 4.9e-06 27.2 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33425.1 - 2.5e-13 50.1 0.3 0.052 13.9 0.0 6.1 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK33425.1 - 5.7e-07 28.8 0.5 0.78 8.6 0.0 4.6 3 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KIK33425.1 - 0.0026 17.4 1.8 0.013 15.1 1.1 2.5 3 1 0 3 3 3 1 PQQ-like domain Cytochrom_D1 PF02239.16 KIK33425.1 - 0.0028 16.3 0.0 0.14 10.7 0.0 2.7 2 1 1 3 3 3 1 Cytochrome D1 heme domain Nup160 PF11715.8 KIK33425.1 - 0.042 12.5 0.2 0.37 9.4 0.1 2.5 2 1 0 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.12 KIK33425.1 - 0.047 13.6 0.1 18 5.4 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Patatin PF01734.22 KIK33425.1 - 0.055 13.6 0.7 0.18 12.0 0.3 1.9 2 0 0 2 2 2 0 Patatin-like phospholipase NuA4 PF09340.10 KIK33425.1 - 0.3 11.0 2.6 0.97 9.4 2.3 2.0 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 Pox_ATPase-GT PF10640.9 KIK33426.1 - 0.072 11.9 0.0 0.072 11.9 0.0 1.0 1 0 0 1 1 1 0 mRNA capping enzyme N-terminal, ATPase and guanylyltransferase zf-C2HC_2 PF13913.6 KIK33431.1 - 0.026 14.4 0.1 0.052 13.5 0.1 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf_C2HC_14 PF18574.1 KIK33431.1 - 0.033 14.0 1.1 0.063 13.1 0.1 1.9 2 0 0 2 2 2 0 C2HC Zing finger domain WD40 PF00400.32 KIK33432.1 - 7.9e-35 118.3 31.2 3.8e-07 30.7 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33432.1 - 2.9e-17 62.7 8.5 3.3e-05 24.1 0.0 4.9 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK33432.1 - 4.7e-07 28.8 11.6 0.2 10.2 0.4 4.3 2 2 3 5 5 5 4 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK33432.1 - 4.3e-06 26.3 2.1 8.4e-05 22.0 0.1 3.0 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 KIK33432.1 - 2.9e-05 23.2 0.3 0.033 13.1 0.0 3.5 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK33432.1 - 0.0081 15.5 0.0 1.3 8.3 0.0 3.1 3 1 1 4 4 4 1 WD40-like domain PD40 PF07676.12 KIK33432.1 - 0.027 14.4 0.3 13 5.9 0.0 3.9 4 1 0 4 4 4 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK33432.1 - 0.082 11.2 0.0 4.1 5.6 0.0 2.1 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Peptidase_S9_N PF02897.15 KIK33432.1 - 0.12 11.1 1.3 0.4 9.4 0.7 2.2 1 1 2 3 3 3 0 Prolyl oligopeptidase, N-terminal beta-propeller domain CPSF_A PF03178.15 KIK33432.1 - 0.19 11.0 0.0 0.45 9.8 0.0 1.6 1 1 0 1 1 1 0 CPSF A subunit region Cellulase PF00150.18 KIK33434.1 - 7.7e-05 22.3 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) KIP1 PF07765.12 KIK33437.1 - 0.076 13.1 0.1 0.087 12.9 0.1 1.1 1 0 0 1 1 1 0 KIP1-like protein Pkinase PF00069.25 KIK33438.1 - 3.5e-15 56.1 0.0 5e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK33438.1 - 1.2e-05 24.8 0.0 2.2e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK33438.1 - 0.0016 17.3 0.0 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FA_desaturase PF00487.24 KIK33439.1 - 1.4e-20 74.3 25.3 6.9e-20 72.0 25.3 1.8 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KIK33439.1 - 0.002 18.3 0.0 0.0043 17.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) D123 PF07065.14 KIK33440.1 - 1.1e-95 320.3 0.0 1.3e-95 320.0 0.0 1.0 1 0 0 1 1 1 1 D123 R2K_3 PF14243.6 KIK33440.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 SDA1 PF05285.12 KIK33441.1 - 0.049 13.1 0.2 0.058 12.8 0.2 1.1 1 0 0 1 1 1 0 SDA1 Amdase PF17645.1 KIK33442.1 - 2.2e-17 63.4 0.0 2.6e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 Arylmalonate decarboxylase HET PF06985.11 KIK33443.1 - 5.8e-09 36.5 1.8 1.1e-05 25.8 0.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 KIK33444.1 - 1.9e-43 148.7 0.0 2.4e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK33444.1 - 1.3e-25 90.2 0.0 1.5e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIK33444.1 - 0.049 13.0 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1088 PF06469.11 KIK33445.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) Thiolase_N PF00108.23 KIK33447.1 - 3.1e-15 56.3 0.1 1.2e-13 51.1 0.1 2.2 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIK33447.1 - 3.4e-05 23.5 0.6 9.4e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIK33447.1 - 0.00041 20.0 1.5 0.033 13.8 0.3 2.4 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KIK33447.1 - 0.0015 18.3 0.1 0.046 13.6 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III WD40 PF00400.32 KIK33448.1 - 1.2e-12 48.1 5.8 4.4e-05 24.2 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33448.1 - 2.5e-08 34.1 0.0 0.047 14.0 0.0 3.1 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK33448.1 - 0.027 13.5 0.0 0.84 8.5 0.0 2.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ldh_1_C PF02866.18 KIK33451.1 - 1.3e-12 47.9 0.0 4.8e-12 46.1 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ABC_tran PF00005.27 KIK33451.1 - 1.5e-05 25.6 0.1 2.9e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KIK33451.1 - 0.01 15.6 0.1 0.026 14.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIK33451.1 - 0.028 14.3 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 KIK33451.1 - 0.12 12.0 0.0 0.29 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain CAV_VP3 PF04771.12 KIK33453.1 - 0.056 13.6 0.0 0.1 12.8 0.0 1.4 1 1 0 1 1 1 0 Chicken anaemia virus VP-3 protein DEAD PF00270.29 KIK33454.1 - 2.1e-11 43.9 0.0 4.9e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK33454.1 - 2.6e-07 31.0 0.0 7e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK33454.1 - 9.5e-05 22.5 0.0 0.00038 20.5 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit OrsD PF12013.8 KIK33454.1 - 0.0053 17.2 1.5 0.017 15.6 1.5 1.8 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D UBN_AB PF14075.6 KIK33455.1 - 1.9e-20 73.5 0.0 3.8e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Ubinuclein conserved middle domain HUN PF08729.10 KIK33455.1 - 4.5e-11 42.6 0.1 1.4e-10 41.0 0.1 1.9 1 0 0 1 1 1 1 HPC2 and ubinuclein domain WD40 PF00400.32 KIK33456.1 - 1.6e-09 38.2 1.0 1.6e-09 38.2 1.0 2.3 2 0 0 2 2 1 1 WD domain, G-beta repeat AAA_16 PF13191.6 KIK33456.1 - 1.9e-06 28.4 0.0 7.9e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KIK33456.1 - 8.2e-06 25.8 0.0 5.4e-05 23.2 0.0 2.3 1 1 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 KIK33456.1 - 0.00087 19.5 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain ATPase_2 PF01637.18 KIK33456.1 - 0.0066 16.4 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA PF00004.29 KIK33456.1 - 0.0089 16.5 0.4 0.035 14.5 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 KIK33456.1 - 0.031 13.4 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 KIK33456.1 - 0.036 14.5 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Ge1_WD40 PF16529.5 KIK33456.1 - 0.037 13.0 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein NB-ARC PF00931.22 KIK33456.1 - 0.045 12.9 0.1 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 KIK33456.1 - 0.051 13.3 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KIK33456.1 - 0.067 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase PIF1 PF05970.14 KIK33456.1 - 0.15 11.2 0.0 0.33 10.1 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase FGase PF05013.12 KIK33456.1 - 0.15 12.3 0.0 0.61 10.3 0.0 1.9 2 0 0 2 2 2 0 N-formylglutamate amidohydrolase KOW PF00467.29 KIK33457.1 - 0.14 12.2 7.8 1.2 9.1 0.2 3.3 3 0 0 3 3 3 0 KOW motif KOW PF00467.29 KIK33458.1 - 2.1e-06 27.4 2.6 0.005 16.7 0.3 3.4 3 0 0 3 3 3 2 KOW motif WD40 PF00400.32 KIK33461.1 - 2.8e-42 141.9 28.0 1.2e-07 32.3 0.3 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33461.1 - 2.9e-18 65.9 5.7 4.6e-05 23.6 0.0 5.3 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK33461.1 - 1.4e-08 33.8 2.4 0.014 14.1 0.1 3.9 3 1 0 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK33461.1 - 4.1e-07 29.3 0.3 0.27 10.1 0.0 4.9 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK33461.1 - 0.00013 21.9 2.1 0.0096 15.8 0.6 3.2 1 1 3 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KIK33461.1 - 0.00032 20.1 0.2 0.51 9.6 0.0 3.4 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal DUF5570 PF17731.1 KIK33461.1 - 0.001 19.1 1.3 1.4 9.0 0.2 2.9 2 1 0 2 2 2 2 Family of unknown function (DUF5570) WD40_like PF17005.5 KIK33461.1 - 0.021 14.2 0.0 9 5.5 0.0 3.0 3 1 0 3 3 3 0 WD40-like domain PALB2_WD40 PF16756.5 KIK33461.1 - 0.049 12.6 0.0 0.049 12.6 0.0 2.8 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain PD40 PF07676.12 KIK33461.1 - 0.065 13.2 0.0 27 4.9 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat DHFR_2 PF06442.11 KIK33461.1 - 0.11 12.4 0.3 18 5.2 0.1 2.6 2 0 0 2 2 2 0 R67 dihydrofolate reductase WD40 PF00400.32 KIK33463.1 - 1.3e-43 146.1 25.6 7.4e-07 29.8 0.4 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33463.1 - 1.3e-19 70.3 2.9 0.0022 18.3 0.1 6.0 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK33463.1 - 3.4e-09 35.9 0.4 0.034 12.8 0.0 4.3 1 1 4 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK33463.1 - 1.7e-08 33.9 0.0 0.15 11.0 0.0 5.7 1 1 6 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK33463.1 - 4.2e-07 30.1 0.0 0.09 12.6 0.0 3.4 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 KIK33463.1 - 1.6e-05 25.2 0.5 6 7.5 0.1 5.0 5 0 0 5 5 5 1 PQQ-like domain WD40_like PF17005.5 KIK33463.1 - 2.5e-05 23.8 0.0 0.19 11.0 0.0 2.8 2 1 1 3 3 3 2 WD40-like domain Nbas_N PF15492.6 KIK33463.1 - 5.6e-05 22.6 1.0 0.31 10.3 0.0 4.6 2 2 4 6 6 6 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 KIK33463.1 - 5.9e-05 21.8 0.3 0.0025 16.4 0.1 2.8 1 1 2 3 3 3 1 Cytochrome D1 heme domain PD40 PF07676.12 KIK33463.1 - 0.00016 21.5 0.1 20 5.3 0.0 4.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PALB2_WD40 PF16756.5 KIK33463.1 - 0.00057 18.9 1.7 0.0041 16.1 1.6 2.4 1 1 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 KIK33463.1 - 0.006 15.0 0.0 2.1 6.6 0.0 2.2 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Peptidase_S9_N PF02897.15 KIK33463.1 - 0.0075 15.1 0.8 0.044 12.6 0.0 2.5 3 1 1 4 4 4 1 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF5570 PF17731.1 KIK33463.1 - 0.023 14.8 2.7 0.57 10.3 0.0 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5570) PQQ PF01011.21 KIK33463.1 - 0.087 12.8 0.3 21 5.3 0.0 4.6 6 0 0 6 6 4 0 PQQ enzyme repeat WD40 PF00400.32 KIK33467.1 - 2e-42 142.3 27.1 1.6e-08 35.1 0.4 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33467.1 - 1e-16 61.0 5.7 0.00039 20.7 0.0 5.2 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK33467.1 - 5.4e-08 31.9 3.5 0.00062 18.5 0.2 3.3 3 1 0 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK33467.1 - 3e-06 26.4 2.1 0.11 11.5 0.1 4.6 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK33467.1 - 9.2e-06 25.2 0.2 0.05 12.9 0.1 2.9 2 2 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK33467.1 - 4e-05 23.1 0.0 0.072 12.4 0.0 2.4 1 1 1 2 2 2 2 WD40-like domain Nucleoporin_N PF08801.11 KIK33467.1 - 0.0015 17.4 1.4 0.78 8.4 0.0 3.5 1 1 3 4 4 4 1 Nup133 N terminal like Cytochrom_D1 PF02239.16 KIK33467.1 - 0.0095 14.5 0.1 0.03 12.9 0.1 1.9 1 1 0 1 1 1 1 Cytochrome D1 heme domain PD40 PF07676.12 KIK33467.1 - 0.013 15.4 0.1 15 5.7 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK33467.1 - 0.13 10.6 0.0 6.3 5.0 0.0 2.7 2 1 2 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz Sec2p PF06428.11 KIK33468.1 - 0.14 12.2 2.4 0.29 11.1 2.4 1.5 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DDE_Tnp_4 PF13359.6 KIK33469.1 - 0.00046 19.9 0.0 0.072 12.7 0.0 2.6 1 1 1 2 2 2 2 DDE superfamily endonuclease DDE_1 PF03184.19 KIK33471.1 - 0.0014 18.3 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_4 PF13359.6 KIK33473.1 - 3.4e-15 56.0 0.0 3.6e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_4 PF13359.6 KIK33474.1 - 1.3e-06 28.1 0.1 1.5e-06 28.0 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KIK33474.1 - 0.00046 19.8 0.1 0.00048 19.8 0.1 1.0 1 0 0 1 1 1 1 Plant transposon protein TB2_DP1_HVA22 PF03134.19 KIK33474.1 - 0.054 13.4 0.0 0.065 13.2 0.0 1.1 1 0 0 1 1 1 0 TB2/DP1, HVA22 family DDE_Tnp_1 PF01609.21 KIK33474.1 - 0.074 12.7 0.0 0.075 12.7 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_4 PF13359.6 KIK33477.1 - 4.5e-16 58.9 0.0 6.6e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KIK33477.1 - 4.5e-05 23.2 0.0 7.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 KIK33478.1 - 5.3e-07 29.4 0.4 5.1e-05 23.0 0.5 2.1 2 0 0 2 2 2 2 DDE superfamily endonuclease Plant_tran PF04827.14 KIK33478.1 - 0.0011 18.6 0.3 0.0016 18.1 0.3 1.1 1 0 0 1 1 1 1 Plant transposon protein DUF2755 PF10954.8 KIK33481.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) DUF5630 PF18632.1 KIK33482.1 - 0.032 13.6 4.0 0.035 13.4 3.4 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5630) Pkinase PF00069.25 KIK33484.1 - 9.1e-05 21.9 0.0 9.8e-05 21.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK33485.1 - 2.7e-16 59.4 0.0 3.4e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 KIK33486.1 - 1.9e-21 76.4 0.0 2.1e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK33486.1 - 0.0055 16.7 0.0 0.0085 16.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIK33486.1 - 0.025 14.0 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain FYDLN_acid PF09538.10 KIK33488.1 - 0.018 15.7 8.0 0.038 14.7 8.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) NPR3 PF03666.13 KIK33488.1 - 0.15 10.8 2.5 0.19 10.5 2.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FancD2 PF14631.6 KIK33488.1 - 1.2 6.4 4.3 1.5 6.1 4.3 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RPN2_C PF18004.1 KIK33488.1 - 1.3 9.0 10.4 3.8 7.4 8.5 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DNA_pol_phi PF04931.13 KIK33488.1 - 3.5 5.6 9.7 4.5 5.3 9.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi CBFD_NFYB_HMF PF00808.23 KIK33491.1 - 1.8e-06 28.1 1.3 0.0094 16.2 0.2 2.1 1 1 1 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK33491.1 - 0.0045 17.3 0.4 0.014 15.7 0.2 1.7 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 zf-C3HC4_3 PF13920.6 KIK33493.1 - 2.3e-10 40.2 10.5 2.3e-10 40.2 10.5 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KIK33493.1 - 6.9e-07 29.3 8.1 6.9e-07 29.3 8.1 2.7 2 1 1 3 3 2 1 FYVE zinc finger Prok-RING_4 PF14447.6 KIK33493.1 - 2.1e-05 24.3 9.9 2.1e-05 24.3 9.9 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KIK33493.1 - 6.7e-05 23.1 10.5 6.7e-05 23.1 10.5 2.5 2 0 0 2 2 2 1 Ring finger domain FYVE_2 PF02318.16 KIK33493.1 - 0.00053 20.2 5.4 0.00053 20.2 5.4 3.0 3 0 0 3 3 2 1 FYVE-type zinc finger DUF1682 PF07946.14 KIK33493.1 - 0.0021 17.3 1.8 0.0028 16.9 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) CAF-1_p150 PF11600.8 KIK33493.1 - 0.014 15.1 16.5 0.019 14.6 16.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Pex26 PF07163.12 KIK33493.1 - 0.083 12.2 2.5 0.12 11.6 2.5 1.2 1 0 0 1 1 1 0 Pex26 protein Presenilin PF01080.17 KIK33493.1 - 0.44 9.3 2.9 0.67 8.7 2.9 1.2 1 0 0 1 1 1 0 Presenilin MCM_bind PF09739.9 KIK33493.1 - 1.3 7.4 5.4 1.9 6.8 5.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor zf-RING_5 PF14634.6 KIK33493.1 - 5.5 7.0 26.9 3.1 7.8 9.7 2.6 2 0 0 2 2 2 0 zinc-RING finger domain RicinB_lectin_2 PF14200.6 KIK33497.1 - 0.00019 22.1 3.1 0.014 16.1 0.4 1.7 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like ubiquitin PF00240.23 KIK33499.1 - 2.6e-26 91.2 0.1 4.7e-26 90.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KIK33499.1 - 8e-09 35.2 0.2 1.5e-08 34.3 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Prok-RING_4 PF14447.6 KIK33499.1 - 0.0019 18.0 11.0 0.0035 17.2 11.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KIK33499.1 - 0.0023 17.8 12.8 0.0038 17.1 12.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK33499.1 - 0.022 14.7 14.5 0.039 13.9 14.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Ubiquitin_2 PF14560.6 KIK33499.1 - 0.059 13.8 0.0 0.15 12.5 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-like domain zf-C3HC4_2 PF13923.6 KIK33499.1 - 1.6 8.7 12.5 2.9 7.8 12.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK33499.1 - 2.3 8.6 14.2 4.7 7.6 14.2 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_6 PF14835.6 KIK33499.1 - 6.5 6.7 9.5 5 7.1 7.1 1.9 1 1 1 2 2 2 0 zf-RING of BARD1-type protein NACHT PF05729.12 KIK33501.1 - 2.2e-08 34.2 0.0 1.2e-07 31.8 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KIK33501.1 - 8.7e-05 23.0 0.0 0.00027 21.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KIK33501.1 - 0.0034 17.7 0.0 0.014 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 KIK33501.1 - 0.042 13.0 0.1 0.077 12.1 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 APS_kinase PF01583.20 KIK33501.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 KIK33501.1 - 0.091 11.9 0.0 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain KDZ PF18758.1 KIK33502.1 - 3.8e-45 154.2 0.0 4.5e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KIK33503.1 - 0.0013 18.3 0.0 0.0017 18.0 0.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK33504.1 - 4e-05 23.7 0.4 5.6e-05 23.2 0.4 1.3 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KIK33504.1 - 0.013 15.6 0.5 0.017 15.3 0.5 1.2 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases Tox-URI2 PF15653.6 KIK33506.1 - 0.0021 18.3 0.6 0.0039 17.4 0.6 1.5 1 0 0 1 1 1 1 URI fold toxin 2 DIM PF08194.12 KIK33508.1 - 0.046 13.9 0.3 0.085 13.1 0.3 1.5 1 0 0 1 1 1 0 DIM protein WD40 PF00400.32 KIK33510.1 - 5.7e-23 80.8 3.4 7.1e-07 29.8 0.2 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33510.1 - 3.2e-10 40.1 0.8 2.7e-07 30.8 0.4 2.9 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK33510.1 - 3.2e-06 26.3 0.0 0.047 12.7 0.0 2.9 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK33510.1 - 0.00023 19.9 0.2 0.19 10.3 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK33510.1 - 0.00039 19.9 0.0 0.021 14.2 0.0 2.1 1 1 1 2 2 2 2 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK33510.1 - 0.0047 16.3 0.0 0.63 9.3 0.0 2.0 2 0 0 2 2 2 2 WD40-like domain PQQ_3 PF13570.6 KIK33510.1 - 0.017 15.6 1.2 37 5.0 1.2 3.1 3 0 0 3 3 3 0 PQQ-like domain WD40 PF00400.32 KIK33511.1 - 1.2e-21 76.6 5.2 2.2e-07 31.5 0.1 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33511.1 - 2e-08 34.4 0.6 0.0054 17.0 0.0 3.3 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK33511.1 - 8.4e-05 21.7 0.0 0.12 11.3 0.0 3.0 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK33511.1 - 0.011 14.5 2.9 0.031 12.9 0.3 2.3 1 1 0 2 2 2 0 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK33511.1 - 0.037 13.9 0.0 1 9.2 0.0 2.0 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK33511.1 - 0.042 13.8 0.0 6.4 6.8 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KIK33511.1 - 0.083 11.4 0.1 4.5 5.7 0.0 2.0 1 1 1 2 2 2 0 Cytochrome D1 heme domain A_deaminase PF00962.22 KIK33512.1 - 1.5e-25 90.3 0.0 1.7e-25 90.1 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 KIK33512.1 - 0.057 12.7 0.0 0.092 12.0 0.0 1.4 1 1 0 1 1 1 0 Amidohydrolase family ABC_membrane PF00664.23 KIK33514.1 - 0.0023 17.6 0.9 0.004 16.8 0.9 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region Mt_ATP-synt_B PF05405.14 KIK33514.1 - 0.041 13.5 0.1 0.26 10.9 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) RNase_H PF00075.24 KIK33515.1 - 1.7e-05 25.1 0.1 2e-05 24.8 0.1 1.5 1 1 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.6 KIK33517.1 - 1.5e-08 34.5 0.3 2.2e-08 33.9 0.3 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KIK33517.1 - 0.00017 21.2 0.0 0.00017 21.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CPP1-like PF11833.8 KIK33518.1 - 5.4 6.6 6.4 0.52 10.0 1.4 1.8 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like FeoC PF09012.10 KIK33519.1 - 0.051 13.6 0.4 0.068 13.3 0.4 1.2 1 0 0 1 1 1 0 FeoC like transcriptional regulator F-box-like PF12937.7 KIK33520.1 - 6.5e-11 41.9 0.7 9e-11 41.5 0.7 1.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK33520.1 - 0.0015 18.4 0.6 1.4 8.9 0.0 2.4 2 0 0 2 2 2 2 F-box domain DAGAT PF03982.13 KIK33522.1 - 1.9e-100 335.6 0.0 2.5e-100 335.2 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.13 KIK33522.1 - 0.89 9.3 6.2 1.7 8.3 6.2 1.4 1 0 0 1 1 1 0 Rer1 family Ubiquitin_2 PF14560.6 KIK33523.1 - 3.2e-26 91.6 0.1 5.2e-26 90.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 KIK33523.1 - 8.3e-26 89.8 0.5 1.5e-25 89.0 0.5 1.4 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.23 KIK33523.1 - 5.7e-05 22.8 0.1 0.00066 19.4 0.1 2.3 1 1 0 1 1 1 1 Ubiquitin family REV PF00424.18 KIK33527.1 - 0.016 15.2 1.9 0.035 14.1 1.9 1.5 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Plavaka PF18759.1 KIK33529.1 - 1.9e-35 122.6 0.0 2.4e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase zf-Mss51 PF13824.6 KIK33533.1 - 0.013 15.5 2.0 0.026 14.6 2.0 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-CCHC_2 PF13696.6 KIK33533.1 - 0.087 12.7 2.6 0.19 11.6 2.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 KIK33533.1 - 2.2 8.5 5.9 4.3 7.6 5.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Retrotran_gag_2 PF14223.6 KIK33534.1 - 2.1e-10 40.4 0.2 2.6e-10 40.1 0.2 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type BTB PF00651.31 KIK33535.1 - 0.00052 20.2 0.1 0.92 9.8 0.0 2.4 1 1 1 2 2 2 2 BTB/POZ domain GST_N_3 PF13417.6 KIK33536.1 - 0.00075 19.9 0.0 0.00093 19.6 0.0 1.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK33536.1 - 0.0011 19.2 0.0 0.0021 18.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK33536.1 - 0.0029 17.9 0.0 0.0037 17.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain zf-C2H2_4 PF13894.6 KIK33537.1 - 0.0048 17.6 2.3 0.13 13.2 0.4 3.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK33537.1 - 0.061 13.8 0.4 0.061 13.8 0.4 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type GAGA PF09237.11 KIK33537.1 - 0.5 10.2 3.3 4.5 7.2 0.6 2.5 1 1 1 2 2 2 0 GAGA factor ESCRT-II PF05871.12 KIK33538.1 - 2.1e-30 105.8 0.1 2.8e-30 105.4 0.1 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit BTB PF00651.31 KIK33539.1 - 1.5e-06 28.4 0.0 1.9e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain Amino_oxidase PF01593.24 KIK33540.1 - 2.2e-05 24.0 0.0 2.5e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase CHAT PF12770.7 KIK33541.1 - 3.1e-32 112.2 0.0 6.3e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK33541.1 - 3.4e-13 49.0 9.2 0.043 13.7 0.0 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIK33541.1 - 1.3e-06 28.6 12.7 3.8 7.9 0.0 8.2 5 3 4 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIK33541.1 - 1.4e-05 24.8 5.3 0.28 11.4 0.1 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK33541.1 - 2.3e-05 24.1 4.6 6.2 7.1 0.0 6.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK33541.1 - 0.0024 17.6 6.5 0.31 10.9 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK33541.1 - 0.0078 16.3 0.4 1.2 9.5 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Zeta_toxin PF06414.12 KIK33541.1 - 0.013 14.8 0.0 0.03 13.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin TPR_11 PF13414.6 KIK33541.1 - 0.017 14.8 0.1 10 5.9 0.0 4.6 4 0 0 4 4 4 0 TPR repeat MIT PF04212.18 KIK33541.1 - 0.024 14.7 0.6 15 5.7 0.1 4.3 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Vta1_C PF18097.1 KIK33541.1 - 0.04 13.6 5.6 0.66 9.7 0.1 4.3 4 0 0 4 4 4 0 Vta1 C-terminal domain Dehydratase_SU PF02287.15 KIK33541.1 - 0.082 13.0 0.0 4.7 7.3 0.0 2.8 2 0 0 2 2 2 0 Dehydratase small subunit TPR_14 PF13428.6 KIK33541.1 - 1 10.3 20.6 53 5.0 0.0 8.4 9 1 1 10 10 9 0 Tetratricopeptide repeat DUF4924 PF16271.5 KIK33542.1 - 0.014 15.4 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4924) NHase_alpha PF02979.16 KIK33543.1 - 0.19 11.0 0.1 0.25 10.6 0.1 1.1 1 0 0 1 1 1 0 Nitrile hydratase, alpha chain WD40 PF00400.32 KIK33546.1 - 8.3e-13 48.6 1.9 5.4e-07 30.2 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33546.1 - 0.046 14.0 0.1 3.2 8.1 0.0 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ret2_MD PF18528.1 KIK33546.1 - 0.046 14.1 0.0 0.067 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA editing 3' terminal uridylyl transferase 2 middle domain WD40 PF00400.32 KIK33548.1 - 2.1e-33 113.8 30.6 3.9e-08 33.8 1.1 5.8 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33548.1 - 1e-14 54.5 3.5 0.00081 19.6 0.3 4.6 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK33548.1 - 1.8e-05 23.8 0.3 0.075 12.0 0.0 4.2 2 1 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK33548.1 - 0.00011 22.1 0.1 0.12 12.3 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK33548.1 - 0.0016 17.2 2.3 0.23 10.0 0.0 3.0 3 1 0 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK33548.1 - 0.014 14.7 0.2 0.075 12.3 0.1 2.2 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KIK33548.1 - 0.016 15.1 0.0 17 5.5 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK33548.1 - 0.019 14.3 0.0 0.17 11.2 0.0 2.1 2 1 0 2 2 2 0 WD40-like domain Cytochrom_D1 PF02239.16 KIK33548.1 - 0.041 12.4 0.2 1 7.8 0.0 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain PALB2_WD40 PF16756.5 KIK33548.1 - 0.42 9.5 9.5 0.51 9.2 0.9 3.1 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain DUF155 PF02582.14 KIK33558.1 - 1.6e-36 126.0 0.0 1.9e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF3808 PF10300.9 KIK33559.1 - 1.3e-52 179.1 0.0 4.5e-42 144.4 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF3808) TPR_2 PF07719.17 KIK33559.1 - 0.0048 16.9 2.3 1.3 9.4 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK33559.1 - 0.0078 16.8 8.7 0.029 15.0 1.3 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat Ribosomal_L5 PF00281.19 KIK33559.1 - 0.18 12.1 0.3 0.47 10.8 0.3 1.7 1 0 0 1 1 1 0 Ribosomal protein L5 DUF1179 PF06678.11 KIK33560.1 - 0.086 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) Imm30 PF15565.6 KIK33560.1 - 0.14 12.3 0.2 3.6 7.7 0.1 2.6 2 0 0 2 2 2 0 Immunity protein 30 WD40 PF00400.32 KIK33561.1 - 1.8e-05 25.4 0.5 7.1e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33561.1 - 0.0011 19.2 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3053 PF11254.8 KIK33561.1 - 0.15 11.6 0.9 2.1 7.9 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3053) WD40 PF00400.32 KIK33562.1 - 3e-19 69.0 3.7 1.6e-09 38.2 0.1 2.0 2 0 0 2 2 2 2 WD domain, G-beta repeat PD40 PF07676.12 KIK33562.1 - 1.1e-05 25.2 0.1 0.17 11.9 0.0 2.5 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 KIK33562.1 - 0.00029 21.1 0.0 0.091 13.1 0.0 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Proteasome_A_N PF10584.9 KIK33562.1 - 0.26 11.0 0.7 2.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature WD40 PF00400.32 KIK33563.1 - 1e-98 320.5 46.6 3.3e-10 40.4 0.2 11.3 11 0 0 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33563.1 - 7.8e-24 83.8 9.9 0.011 16.0 0.1 9.5 1 1 8 9 9 9 7 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KIK33563.1 - 5.4e-14 51.8 13.4 0.11 11.2 0.0 9.6 1 1 7 8 8 8 5 Nup133 N terminal like WD40_like PF17005.5 KIK33563.1 - 1.6e-13 50.6 0.2 0.041 13.2 0.0 7.8 6 2 2 8 8 8 2 WD40-like domain Ge1_WD40 PF16529.5 KIK33563.1 - 2e-13 50.0 6.7 0.068 12.1 0.0 9.1 1 1 9 11 11 11 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK33563.1 - 7.6e-11 41.3 15.1 1.5 7.3 0.1 10.5 5 3 4 11 11 11 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KIK33563.1 - 1.6e-09 37.8 4.8 9.6 6.3 0.0 9.9 11 0 0 11 11 11 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.6 KIK33563.1 - 2.6e-07 30.9 9.6 4.9 7.8 0.0 9.1 6 3 4 10 10 10 1 PQQ-like domain PD40 PF07676.12 KIK33563.1 - 5.5e-06 26.2 8.7 16 5.6 0.0 9.1 11 0 0 11 11 10 0 WD40-like Beta Propeller Repeat Peptidase_S9_N PF02897.15 KIK33563.1 - 2e-05 23.6 0.6 8.5 5.1 0.0 6.2 4 2 2 6 6 6 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Frtz PF11768.8 KIK33563.1 - 7.7e-05 21.2 0.0 5.8 5.1 0.0 5.2 2 2 3 6 6 6 2 WD repeat-containing and planar cell polarity effector protein Fritz DUF5570 PF17731.1 KIK33563.1 - 0.00082 19.5 16.2 0.11 12.5 0.4 5.5 3 1 3 6 6 6 2 Family of unknown function (DUF5570) DUF4402 PF14352.6 KIK33563.1 - 0.00091 19.9 10.5 3.3 8.4 1.3 5.2 2 2 2 5 5 5 1 Domain of unknown function (DUF4402) Ret2_MD PF18528.1 KIK33563.1 - 0.0067 16.8 0.2 18 5.8 0.0 4.7 4 2 1 5 5 4 0 RNA editing 3' terminal uridylyl transferase 2 middle domain DHFR_2 PF06442.11 KIK33563.1 - 0.018 14.8 0.2 31 4.5 0.0 3.8 3 1 1 4 4 4 0 R67 dihydrofolate reductase PQQ PF01011.21 KIK33563.1 - 0.043 13.8 0.1 2.8e+02 1.7 0.0 5.8 7 0 0 7 7 6 0 PQQ enzyme repeat Cuticle_4 PF15955.5 KIK33563.1 - 0.051 14.3 13.1 37 5.1 0.0 7.5 10 0 0 10 10 9 0 Cuticle protein PS_Dcarbxylase PF02666.15 KIK33563.1 - 0.11 12.1 0.7 35 3.8 0.0 3.4 3 1 1 4 4 4 0 Phosphatidylserine decarboxylase Sirohm_synth_M PF14824.6 KIK33563.1 - 0.51 9.8 5.5 3.7 7.1 0.2 4.0 4 0 0 4 4 4 0 Sirohaem biosynthesis protein central AAA_assoc_2 PF16193.5 KIK33564.1 - 0.061 13.7 0.0 0.082 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA C-terminal domain DUF2660 PF10859.8 KIK33567.1 - 0.087 13.3 0.3 0.14 12.7 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2660) Pkinase PF00069.25 KIK33570.1 - 2e-20 73.3 0.0 2.4e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK33570.1 - 2.6e-09 36.8 0.0 3.4e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK33570.1 - 9.7e-07 27.9 0.1 1.2e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KIK33570.1 - 0.0038 16.9 0.0 0.0057 16.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIK33570.1 - 0.014 15.3 0.2 2 8.2 0.1 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KIK33570.1 - 0.13 11.6 0.1 0.37 10.1 0.1 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family VPS53_C PF16854.5 KIK33570.1 - 0.21 11.4 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus DUF1073 PF06381.11 KIK33571.1 - 0.0093 14.8 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1073) AAA_PrkA PF08298.11 KIK33572.1 - 0.061 12.2 0.0 0.067 12.1 0.0 1.0 1 0 0 1 1 1 0 PrkA AAA domain Prefoldin PF02996.17 KIK33573.1 - 7.4e-18 64.6 0.0 8.9e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF3089 PF11288.8 KIK33573.1 - 0.089 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Spore_SspJ PF09575.10 KIK33573.1 - 0.15 12.4 0.1 0.3 11.5 0.1 1.5 1 0 0 1 1 1 0 Small spore protein J (Spore_SspJ) KOW PF00467.29 KIK33574.1 - 1.3e-08 34.5 17.1 0.0017 18.2 0.6 6.2 6 0 0 6 6 6 3 KOW motif ProQ_C PF17516.2 KIK33574.1 - 0.22 11.0 0.8 18 4.9 0.0 3.2 4 0 0 4 4 4 0 ProQ C-terminal domain NACHT PF05729.12 KIK33577.1 - 1.1e-08 35.2 0.0 1.7e-08 34.6 0.0 1.3 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK33577.1 - 3.6e-06 27.4 0.0 6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK33577.1 - 4.2e-05 24.0 0.0 8e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KIK33577.1 - 0.00078 20.0 0.0 0.0011 19.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KIK33577.1 - 0.0048 16.8 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase ResIII PF04851.15 KIK33577.1 - 0.01 15.9 0.2 0.013 15.5 0.2 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NB-ARC PF00931.22 KIK33577.1 - 0.015 14.5 0.0 0.019 14.2 0.0 1.3 1 1 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.14 KIK33577.1 - 0.019 14.2 0.6 0.57 9.4 0.1 2.0 1 1 1 2 2 2 0 KAP family P-loop domain AAA_7 PF12775.7 KIK33577.1 - 0.022 14.3 0.1 0.033 13.7 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region RuvB_N PF05496.12 KIK33577.1 - 0.023 14.5 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KIK33577.1 - 0.042 14.1 0.0 0.062 13.6 0.0 1.3 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 KIK33577.1 - 0.049 12.8 0.0 0.049 12.8 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 KIK33577.1 - 0.053 13.4 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KIK33577.1 - 0.054 12.7 0.0 0.054 12.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.15 KIK33577.1 - 0.054 12.8 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_14 PF13173.6 KIK33577.1 - 0.06 13.4 0.2 0.23 11.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIK33577.1 - 0.061 13.0 0.0 0.13 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KIK33577.1 - 0.077 12.4 0.2 0.15 11.5 0.1 1.7 1 1 1 2 2 2 0 PhoH-like protein RNA_helicase PF00910.22 KIK33577.1 - 0.084 13.3 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 KIK33577.1 - 0.087 12.7 0.1 0.2 11.6 0.1 1.7 1 1 0 1 1 1 0 NTPase Parvo_NS1 PF01057.17 KIK33577.1 - 0.094 11.8 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 KIK33577.1 - 0.097 12.7 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KIK33577.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KIK33577.1 - 0.13 12.0 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain CxC6 PF18721.1 KIK33578.1 - 7e-15 55.0 0.8 7e-15 55.0 0.8 2.5 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases CxC5 PF18718.1 KIK33578.1 - 1.3e-09 38.1 0.6 3.1e-09 36.9 0.6 1.6 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases Auto_anti-p27 PF06677.12 KIK33578.1 - 0.62 10.3 2.3 0.6 10.3 0.2 2.1 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) RIX1 PF08167.12 KIK33581.1 - 0.058 13.1 0.0 0.067 12.9 0.0 1.1 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis CHAT PF12770.7 KIK33583.1 - 1.2e-08 34.7 0.0 8.7e-07 28.6 0.0 2.1 1 1 1 2 2 2 2 CHAT domain TauD PF02668.16 KIK33584.1 - 0.041 13.7 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family DDE_1 PF03184.19 KIK33586.1 - 0.0036 17.0 0.1 0.0047 16.6 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Zn_clus PF00172.18 KIK33588.1 - 0.064 13.4 13.0 0.82 9.9 4.5 2.5 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 KIK33591.1 - 8.5e-11 41.6 0.0 9.2e-11 41.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MCPVI PF02993.14 KIK33594.1 - 2.4 8.0 8.5 0.31 10.8 3.4 1.9 2 0 0 2 2 2 0 Minor capsid protein VI AAA PF00004.29 KIK33595.1 - 0.0025 18.3 0.0 0.0032 17.9 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIK33595.1 - 0.0047 16.9 0.0 0.0061 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KIK33595.1 - 0.069 12.9 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain Stb3 PF10330.9 KIK33595.1 - 0.074 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative Sin3 binding protein Plavaka PF18759.1 KIK33597.1 - 3e-35 122.0 0.0 5.4e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase SDA1 PF05285.12 KIK33597.1 - 0.045 13.2 4.5 0.082 12.3 4.5 1.4 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 KIK33597.1 - 7.6 5.8 11.5 14 5.0 11.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Phenyl_P_gamma PF09662.10 KIK33599.1 - 0.19 11.9 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) EOS1 PF12326.8 KIK33601.1 - 6.4e-27 94.6 18.7 8.6e-18 64.9 4.7 3.7 1 1 0 2 2 2 2 N-glycosylation protein CHZ PF09649.10 KIK33601.1 - 0.029 13.8 1.1 0.078 12.5 1.1 1.6 1 0 0 1 1 1 0 Histone chaperone domain CHZ Retrotran_gag_2 PF14223.6 KIK33604.1 - 8e-08 32.0 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type PolC_DP2 PF03833.13 KIK33604.1 - 0.18 9.7 0.9 0.24 9.2 0.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Toxin_22 PF08092.11 KIK33604.1 - 0.69 10.0 8.0 1.2 9.3 8.0 1.3 1 0 0 1 1 1 0 Magi peptide toxin family Ndc1_Nup PF09531.10 KIK33606.1 - 1.8 7.1 5.1 2 7.0 5.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Exo_endo_phos PF03372.23 KIK33607.1 - 0.00017 21.2 0.1 0.00042 19.9 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SPEG_u2 PF16650.5 KIK33608.1 - 0.039 14.1 0.3 0.074 13.3 0.3 1.4 1 0 0 1 1 1 0 Unstructured region on SPEG complex protein RVT_1 PF00078.27 KIK33609.1 - 4.5e-06 26.3 0.0 7.2e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 KIK33610.1 - 0.03 14.5 0.0 0.035 14.3 0.0 1.1 1 0 0 1 1 1 0 RNase H zf-RVT PF13966.6 KIK33611.1 - 0.00029 21.5 2.5 0.00085 20.0 0.1 2.6 2 2 0 2 2 2 1 zinc-binding in reverse transcriptase KDZ PF18758.1 KIK33613.1 - 1.9e-07 30.9 3.6 2.5e-07 30.6 3.6 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Asp PF00026.23 KIK33614.1 - 4.9e-47 160.9 15.6 1.1e-46 159.8 15.6 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK33614.1 - 3.5e-11 43.6 4.9 6.3e-05 23.3 1.1 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 KIK33614.1 - 0.0019 18.7 1.3 0.067 13.8 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIK33614.1 - 0.019 15.6 4.5 0.46 11.2 0.4 2.9 2 1 1 3 3 3 0 Aspartyl protease Asp PF00026.23 KIK33615.1 - 4.2e-46 157.8 12.8 8.4e-46 156.8 12.8 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK33615.1 - 5.5e-09 36.5 2.2 9.4e-05 22.7 0.4 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK33615.1 - 0.029 15.0 3.2 0.22 12.2 0.2 2.7 2 0 0 2 2 2 0 Aspartyl protease AAA PF00004.29 KIK33616.1 - 4.3e-93 308.7 0.0 9.8e-48 161.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIK33616.1 - 1.3e-20 72.9 0.5 1.5e-10 40.7 0.2 2.8 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KIK33616.1 - 3.1e-14 53.0 0.0 1.7e-06 27.9 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KIK33616.1 - 1.5e-12 48.2 3.3 0.00023 21.6 0.2 5.2 3 2 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 KIK33616.1 - 1.7e-10 41.3 0.9 0.022 15.1 0.0 4.8 3 2 1 4 4 3 2 AAA domain AAA_33 PF13671.6 KIK33616.1 - 3.2e-10 40.3 0.0 0.00015 21.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KIK33616.1 - 4.6e-10 39.6 0.7 0.0029 17.6 0.0 4.7 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIK33616.1 - 6.7e-10 39.4 0.0 0.00081 19.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 KIK33616.1 - 5e-09 35.8 0.0 7.2e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 KIK33616.1 - 1e-07 32.3 0.0 0.025 15.0 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 KIK33616.1 - 2.4e-07 30.8 0.0 0.033 14.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KIK33616.1 - 4.4e-07 29.8 0.0 0.02 14.6 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 KIK33616.1 - 5.9e-07 29.1 0.4 0.032 13.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KIK33616.1 - 1.3e-06 28.7 0.0 0.031 14.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KIK33616.1 - 3.8e-06 26.9 0.4 0.1 12.5 0.0 3.6 3 1 1 4 4 3 2 NACHT domain ABC_tran PF00005.27 KIK33616.1 - 7e-06 26.6 0.0 0.15 12.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter Cytidylate_kin2 PF13189.6 KIK33616.1 - 8.3e-06 26.0 0.0 0.0075 16.4 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family TsaE PF02367.17 KIK33616.1 - 8.9e-06 25.7 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KIK33616.1 - 1e-05 25.4 0.0 0.025 14.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KIK33616.1 - 1.9e-05 25.2 0.0 0.33 11.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 KIK33616.1 - 4.7e-05 23.4 0.0 0.15 12.0 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_17 PF13207.6 KIK33616.1 - 5.5e-05 23.6 0.0 0.078 13.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KIK33616.1 - 6.7e-05 22.3 0.1 1.1 8.6 0.0 3.2 2 1 0 3 3 3 2 KaiC Zeta_toxin PF06414.12 KIK33616.1 - 7.3e-05 22.1 0.0 0.43 9.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.6 KIK33616.1 - 0.00012 21.8 1.1 2.8 7.4 0.0 4.1 3 1 0 4 4 4 2 AAA domain Sigma54_activat PF00158.26 KIK33616.1 - 0.00012 21.8 0.0 0.45 10.2 0.0 3.1 3 0 0 3 3 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 KIK33616.1 - 0.00015 21.3 0.0 0.63 9.5 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 KIK33616.1 - 0.0002 21.5 0.0 1.1 9.4 0.0 3.2 3 0 0 3 3 3 2 Sigma-54 interaction domain Viral_helicase1 PF01443.18 KIK33616.1 - 0.00041 20.2 0.0 0.66 9.7 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KIK33616.1 - 0.00051 19.3 0.0 0.94 8.6 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain DUF815 PF05673.13 KIK33616.1 - 0.00053 19.2 0.0 0.011 15.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 KIK33616.1 - 0.0014 17.8 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 KIK33616.1 - 0.0015 18.3 0.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KIK33616.1 - 0.0021 18.0 0.0 2 8.3 0.0 3.0 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea PhoH PF02562.16 KIK33616.1 - 0.0029 17.1 0.2 2.3 7.6 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_24 PF13479.6 KIK33616.1 - 0.0035 17.1 0.0 0.94 9.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain SKI PF01202.22 KIK33616.1 - 0.0038 17.4 0.0 3.6 7.7 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase DUF2075 PF09848.9 KIK33616.1 - 0.026 13.8 0.0 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AFG1_ATPase PF03969.16 KIK33616.1 - 0.026 13.4 0.0 1.4 7.8 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase NTPase_1 PF03266.15 KIK33616.1 - 0.026 14.4 0.0 6.7 6.6 0.0 2.6 2 0 0 2 2 2 0 NTPase Bac_DnaA PF00308.18 KIK33616.1 - 0.038 13.8 0.0 4.7 7.0 0.0 2.7 3 1 0 3 3 2 0 Bacterial dnaA protein PduV-EutP PF10662.9 KIK33616.1 - 0.055 13.2 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 KIK33616.1 - 0.064 13.6 1.0 21 5.4 0.3 2.9 2 1 0 2 2 2 0 AAA domain Vps4_C PF09336.10 KIK33616.1 - 0.085 12.9 0.1 13 5.9 0.0 2.7 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain SRPRB PF09439.10 KIK33616.1 - 0.095 12.1 0.0 13 5.2 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KIK33616.1 - 0.12 12.5 0.0 3.5 7.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase IPT PF01745.16 KIK33616.1 - 0.14 11.5 0.1 11 5.3 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase CPT PF07931.12 KIK33616.1 - 0.16 11.8 0.0 3.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein TMEM173 PF15009.6 KIK33617.1 - 0.067 12.3 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 173 Cwf_Cwc_15 PF04889.12 KIK33619.1 - 0.23 11.1 3.9 0.34 10.6 3.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sec10 PF07393.11 KIK33620.1 - 0.18 10.2 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Glyco_hydro_3 PF00933.21 KIK33625.1 - 3.4e-13 49.7 0.0 4.1e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain CAAD PF14159.6 KIK33628.1 - 0.87 9.5 4.8 0.3 11.0 1.4 2.0 1 1 1 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase PRA1 PF03208.19 KIK33628.1 - 1.9 8.1 9.9 2 8.0 1.6 2.2 2 0 0 2 2 2 0 PRA1 family protein UvdE PF03851.14 KIK33630.1 - 0.00023 20.5 0.7 0.00023 20.5 0.7 1.0 1 0 0 1 1 1 1 UV-endonuclease UvdE P22_AR_N PF10547.9 KIK33630.1 - 0.06 13.7 0.1 0.061 13.6 0.1 1.1 1 0 0 1 1 1 0 P22_AR N-terminal domain Questin_oxidase PF14027.6 KIK33631.1 - 2.9e-89 300.0 0.0 3.5e-89 299.7 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like SRP-alpha_N PF04086.13 KIK33636.1 - 0.13 12.1 5.2 0.16 11.9 5.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SOG2 PF10428.9 KIK33636.1 - 0.71 9.0 6.8 0.8 8.8 6.8 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF515 PF04415.12 KIK33636.1 - 0.76 8.1 4.6 0.85 7.9 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Apt1 PF10351.9 KIK33636.1 - 3 6.6 5.7 3 6.6 5.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KIK33636.1 - 3 6.3 5.9 3 6.3 5.9 1.1 1 0 0 1 1 1 0 Macoilin family Plavaka PF18759.1 KIK33637.1 - 1.1e-10 41.2 0.1 2.1e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Plavaka transposase Proteasom_Rpn13 PF04683.13 KIK33639.1 - 3.9e-26 91.4 0.0 5.8e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 KIK33639.1 - 3.8e-23 81.8 0.3 6.4e-23 81.1 0.3 1.3 1 0 0 1 1 1 1 UCH-binding domain CHAT PF12770.7 KIK33641.1 - 3.1e-42 145.0 0.0 8.7e-42 143.5 0.0 1.7 2 0 0 2 2 2 1 CHAT domain TPR_10 PF13374.6 KIK33641.1 - 3.4e-21 74.4 24.0 0.0012 18.6 0.1 12.9 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_12 PF13424.6 KIK33641.1 - 8e-06 26.1 29.7 1.3 9.3 0.6 11.8 7 3 5 12 12 12 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK33641.1 - 0.00033 20.5 3.2 22 5.4 0.0 8.3 9 0 0 9 9 9 1 Tetratricopeptide repeat DUF4471 PF14740.6 KIK33641.1 - 0.0014 17.9 0.0 3.4 6.8 0.0 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF4471) ACT_6 PF13740.6 KIK33641.1 - 0.041 13.9 0.2 1.7 8.7 0.0 3.2 2 0 0 2 2 2 0 ACT domain TPR_2 PF07719.17 KIK33641.1 - 0.11 12.7 7.2 54 4.3 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.32 KIK33642.1 - 1.5e-05 25.6 1.0 2.3e-05 25.0 1.0 1.3 1 0 0 1 1 1 1 WD domain, G-beta repeat Nup160 PF11715.8 KIK33642.1 - 0.00039 19.2 0.0 0.00048 18.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK33642.1 - 0.046 13.0 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 WD40-like domain MRP-L27 PF09809.9 KIK33644.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 F-box-like PF12937.7 KIK33644.1 - 0.11 12.5 0.1 0.35 10.8 0.1 2.0 1 0 0 1 1 1 0 F-box-like Clostridium_P47 PF06597.11 KIK33644.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Clostridium P-47 protein HET PF06985.11 KIK33647.1 - 0.00017 22.0 0.1 0.00052 20.4 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AA_permease PF00324.21 KIK33649.1 - 2.3e-32 112.2 7.5 3e-32 111.8 7.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK33649.1 - 2e-13 50.0 8.3 2.2e-13 49.9 8.3 1.0 1 0 0 1 1 1 1 Amino acid permease Oxidored_q4 PF00507.19 KIK33649.1 - 4.4 7.5 12.5 3.5 7.8 5.7 2.8 2 2 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 PLA2_B PF01735.18 KIK33650.1 - 7.8e-105 351.1 1.5 1e-104 350.7 1.5 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain p450 PF00067.22 KIK33653.1 - 7e-62 209.7 0.0 9.7e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 KIK33655.1 - 5e-41 137.9 23.0 3.5e-09 37.1 2.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33655.1 - 9.3e-18 64.3 8.4 0.00016 21.9 0.1 5.6 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK33655.1 - 8.7e-09 34.6 7.5 0.00033 19.4 0.5 4.2 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK33655.1 - 2.6e-06 26.7 0.1 0.38 9.7 0.1 4.5 2 2 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK33655.1 - 3.3e-05 23.4 1.2 0.00063 19.2 0.1 3.1 1 1 3 4 4 4 1 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 KIK33655.1 - 0.0025 17.8 0.6 0.11 12.4 0.1 2.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 KIK33655.1 - 0.0053 16.1 0.7 0.063 12.5 0.2 2.5 3 0 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF1513 PF07433.11 KIK33655.1 - 0.0069 15.5 0.4 1.8 7.6 0.0 2.6 1 1 2 3 3 3 2 Protein of unknown function (DUF1513) IKI3 PF04762.12 KIK33655.1 - 0.012 13.6 0.2 0.13 10.2 0.0 2.1 1 1 1 2 2 2 0 IKI3 family Cytochrom_D1 PF02239.16 KIK33655.1 - 0.019 13.5 0.0 1.1 7.7 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain WD40_like PF17005.5 KIK33655.1 - 0.034 13.5 0.0 0.59 9.4 0.0 2.7 2 1 0 3 3 3 0 WD40-like domain Frtz PF11768.8 KIK33655.1 - 0.071 11.4 0.0 0.62 8.3 0.0 2.3 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 KIK33656.1 - 8.6e-43 143.5 26.9 4.4e-07 30.5 1.4 6.4 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33656.1 - 8.8e-24 83.6 1.8 0.00011 22.4 0.0 6.0 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KIK33656.1 - 7.8e-12 45.1 0.4 0.0045 16.4 0.0 4.8 1 1 4 5 5 5 4 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 KIK33656.1 - 7.3e-10 38.3 0.0 0.082 11.9 0.0 5.6 1 1 5 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK33656.1 - 1.1e-07 30.9 0.2 1.1 7.8 0.0 4.1 3 1 0 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK33656.1 - 0.00051 19.5 0.0 2.8 7.2 0.0 3.9 2 1 2 4 4 4 2 WD40-like domain Nucleoporin_N PF08801.11 KIK33656.1 - 0.0025 16.6 0.0 4.9 5.8 0.0 3.5 1 1 2 4 4 4 1 Nup133 N terminal like IKI3 PF04762.12 KIK33656.1 - 0.003 15.6 0.0 0.58 8.1 0.0 2.7 1 1 1 3 3 3 2 IKI3 family Cytochrom_D1 PF02239.16 KIK33656.1 - 0.014 13.9 0.2 0.14 10.7 0.1 2.3 2 1 1 3 3 3 0 Cytochrome D1 heme domain PD40 PF07676.12 KIK33656.1 - 0.022 14.7 1.3 52 3.9 0.0 4.8 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat SGP PF17228.2 KIK33656.1 - 0.081 13.8 0.4 14 6.6 0.0 2.9 2 2 1 3 3 3 0 Sulphur globule protein DUF4082 PF13313.6 KIK33656.1 - 0.082 12.9 0.5 1.1 9.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4082) KDZ PF18758.1 KIK33659.1 - 4.9e-70 235.6 0.8 4.9e-70 235.6 0.8 1.7 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase Glyco_hydro_36N PF16875.5 KIK33659.1 - 0.063 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 36 N-terminal domain JUPITER PF17054.5 KIK33661.1 - 0.01 15.3 0.1 0.01 15.3 0.1 1.1 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter DUF1979 PF09322.10 KIK33662.1 - 0.087 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1979) F-box PF00646.33 KIK33665.1 - 6.3e-05 22.7 0.3 0.00014 21.6 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK33665.1 - 0.0021 17.9 1.0 0.0062 16.4 1.0 1.8 1 0 0 1 1 1 1 F-box-like SRP_TPR_like PF17004.5 KIK33666.1 - 7.1e-15 55.1 0.7 1.1e-14 54.5 0.7 1.2 1 0 0 1 1 1 1 Putative TPR-like repeat SRP72 PF08492.12 KIK33666.1 - 6.8e-08 32.8 1.7 6.8e-08 32.8 1.7 2.2 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_16 PF13432.6 KIK33666.1 - 4.4e-05 24.0 4.4 0.03 14.9 2.6 2.4 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK33666.1 - 5.5e-05 23.0 5.2 4.9 7.5 0.4 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIK33666.1 - 0.00036 21.1 4.9 0.9 10.5 0.0 3.8 1 1 3 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KIK33666.1 - 0.0018 17.5 2.8 0.33 10.1 1.6 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK33666.1 - 0.0037 17.8 8.8 0.035 14.6 0.2 3.1 1 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK33666.1 - 0.019 15.2 5.9 0.25 11.6 1.8 2.3 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KIK33666.1 - 0.055 14.1 2.2 23 5.9 0.3 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 KIK33666.1 - 0.072 13.2 1.7 0.21 11.7 0.1 2.3 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK33666.1 - 0.075 12.9 1.5 2 8.4 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIK33666.1 - 0.082 13.0 3.6 5.2 7.2 0.0 3.6 2 1 2 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 KIK33666.1 - 0.14 12.4 2.4 5.5 7.5 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Pinin_SDK_memA PF04696.13 KIK33667.1 - 2.5e-15 56.7 13.7 2.5e-15 56.7 13.7 3.0 2 1 0 2 2 2 1 pinin/SDK/memA/ protein conserved region DUF4746 PF15928.5 KIK33667.1 - 0.0044 16.5 3.6 0.0044 16.5 3.6 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4746) KDZ PF18758.1 KIK33669.1 - 1.6e-44 152.2 0.0 9.3e-44 149.7 0.0 2.1 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DND1_DSRM PF14709.7 KIK33670.1 - 0.058 13.6 0.2 0.16 12.3 0.2 1.7 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 CDC45 PF02724.14 KIK33672.1 - 10 4.3 9.6 12 4.1 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein ACR_tran PF00873.19 KIK33673.1 - 0.62 7.6 2.5 0.82 7.2 2.5 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF4218 PF13960.6 KIK33675.1 - 0.00025 20.7 0.0 0.00051 19.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.14 KIK33675.1 - 0.00038 19.8 0.0 0.00072 18.9 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4715 PF15835.5 KIK33675.1 - 0.012 15.7 0.0 0.036 14.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4715) DNA_pol_B PF00136.21 KIK33675.1 - 0.19 10.4 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase family B WD40 PF00400.32 KIK33678.1 - 4.9e-08 33.5 0.1 9.8e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33678.1 - 0.025 14.9 0.1 0.027 14.7 0.1 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK33678.1 - 0.04 12.6 0.1 0.04 12.6 0.1 1.0 1 0 0 1 1 1 0 Nucleoporin Nup120/160 NopRA1 PF16201.5 KIK33680.1 - 4.4e-40 137.4 0.9 5.4e-40 137.1 0.9 1.1 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 HEAT PF02985.22 KIK33680.1 - 0.016 15.4 0.7 0.67 10.4 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat DASH_Dam1 PF08653.10 KIK33681.1 - 0.0096 15.7 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 Amino_oxidase PF01593.24 KIK33682.1 - 1.9e-32 113.1 0.0 2.7e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK33682.1 - 2.8e-08 33.9 0.0 6.9e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIK33682.1 - 0.0015 17.4 0.2 1.2 7.8 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 KIK33682.1 - 0.013 14.8 0.4 0.12 11.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK33682.1 - 0.027 15.0 0.3 12 6.5 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK33682.1 - 0.057 12.7 0.0 6 6.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TFIID_NTD2 PF04494.15 KIK33683.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain Plavaka PF18759.1 KIK33685.1 - 1.1e-27 97.1 0.0 1.9e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase CobT PF06213.12 KIK33685.1 - 3.2 7.1 10.5 5.9 6.2 10.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 KIK33685.1 - 4.7 6.6 8.7 8.9 5.6 8.7 1.3 1 0 0 1 1 1 0 SDA1 PTCB-BRCT PF12738.7 KIK33686.1 - 7.9e-33 112.2 0.1 1.2e-11 44.4 0.0 3.8 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 KIK33686.1 - 8.3e-27 93.4 0.0 6e-08 33.0 0.0 4.2 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KIK33686.1 - 1.5e-09 38.1 0.0 0.04 14.3 0.0 4.3 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KIK33686.1 - 6.7e-06 26.3 0.0 0.0035 17.6 0.0 3.8 4 0 0 4 4 4 1 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KIK33686.1 - 3.2e-05 23.7 0.0 0.32 10.9 0.0 2.9 3 0 0 3 3 3 2 Regulator of Ty1 transposition protein 107 BRCT domain NIBRIN_BRCT_II PF16508.5 KIK33686.1 - 0.18 12.1 0.0 0.5 10.7 0.0 1.7 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein YIF1 PF03878.15 KIK33687.1 - 0.98 8.9 8.7 0.95 8.9 7.4 1.6 1 1 0 1 1 1 0 YIF1 DUF1751 PF08551.10 KIK33687.1 - 2 9.0 12.2 0.52 10.9 5.7 2.7 1 1 1 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) MMS1_N PF10433.9 KIK33688.1 - 0.1 11.2 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Asp_protease_2 PF13650.6 KIK33691.1 - 0.021 15.5 0.0 0.16 12.6 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 KIK33691.1 - 0.084 13.4 0.1 1.4 9.6 0.0 2.7 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease DUF1966 PF09260.11 KIK33691.1 - 0.11 12.7 0.5 16 5.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1966) Dimer_Tnp_hAT PF05699.14 KIK33692.1 - 7.1e-10 38.6 0.5 1.6e-09 37.5 0.1 1.8 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region OmpW PF03922.14 KIK33692.1 - 0.14 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 OmpW family Peptidase_S9 PF00326.21 KIK33693.1 - 2.2e-09 37.1 0.4 1.3e-08 34.6 0.4 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family KIX PF02172.16 KIK33694.1 - 0.017 15.4 0.0 1.4 9.2 0.0 2.2 2 0 0 2 2 2 0 KIX domain NifU PF01106.17 KIK33694.1 - 0.07 13.3 0.0 18 5.6 0.0 2.5 2 0 0 2 2 2 0 NifU-like domain ChW PF07538.11 KIK33694.1 - 7.7 6.5 7.1 15 5.6 0.6 2.8 2 0 0 2 2 2 0 Clostridial hydrophobic W TMA7 PF09072.10 KIK33695.1 - 1.2e-23 83.7 22.2 1.3e-23 83.6 22.2 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Striatin PF08232.12 KIK33696.1 - 7.5e-51 172.8 0.0 7.5e-51 172.8 0.0 3.0 3 0 0 3 3 3 1 Striatin family WD40 PF00400.32 KIK33696.1 - 8.9e-21 73.8 1.8 1.2e-06 29.1 0.0 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat TFIIA PF03153.13 KIK33696.1 - 0.00058 20.0 29.1 0.054 13.5 5.6 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit ANAPC4_WD40 PF12894.7 KIK33696.1 - 0.0062 16.8 0.0 0.48 10.8 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KIK33696.1 - 0.017 13.9 0.0 0.087 11.5 0.0 1.9 1 1 0 1 1 1 0 Nup133 N terminal like WD40 PF00400.32 KIK33703.1 - 2.6e-10 40.7 0.2 0.085 13.8 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat p450 PF00067.22 KIK33706.1 - 1.9e-11 43.4 0.1 2.3e-11 43.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Dimer_Tnp_hAT PF05699.14 KIK33711.1 - 1.3e-15 56.9 0.0 1.4e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HTH_Tnp_Tc5 PF03221.16 KIK33713.1 - 0.012 15.6 2.0 0.015 15.3 0.1 2.0 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain DUF1045 PF06299.12 KIK33713.1 - 0.14 12.1 0.6 0.22 11.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) DDE_1 PF03184.19 KIK33714.1 - 6.8e-27 94.2 0.0 1.2e-26 93.4 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KIK33714.1 - 0.012 15.3 0.2 0.14 11.9 0.1 2.4 1 1 0 1 1 1 0 DDE superfamily endonuclease FAD_binding_3 PF01494.19 KIK33716.1 - 5.9e-56 190.2 0.0 7.6e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KIK33716.1 - 2e-06 26.8 0.4 2.8e-06 26.3 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KIK33716.1 - 3.4e-06 26.4 0.4 5.3e-06 25.8 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KIK33716.1 - 3.9e-06 26.3 0.0 5.4e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KIK33716.1 - 2.5e-05 24.4 0.1 4.9e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK33716.1 - 4.3e-05 22.9 0.0 6.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK33716.1 - 6.8e-05 23.4 0.0 0.0016 19.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIK33716.1 - 0.0002 20.4 0.0 0.00027 19.9 0.0 1.1 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.12 KIK33716.1 - 0.00037 19.7 0.4 0.00053 19.2 0.4 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KIK33716.1 - 0.00047 19.5 0.0 0.00071 18.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK33716.1 - 0.0022 17.7 0.1 0.0043 16.7 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIK33716.1 - 0.016 15.2 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.22 KIK33716.1 - 0.017 14.2 0.3 0.025 13.7 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KIK33716.1 - 0.017 14.5 0.1 0.024 14.0 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KIK33716.1 - 0.026 13.8 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KIK33716.1 - 0.041 13.8 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KIK33716.1 - 0.11 13.0 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 KIK33716.1 - 0.15 11.7 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HsdM_N PF12161.8 KIK33717.1 - 0.11 13.1 0.1 0.44 11.2 0.0 2.1 2 1 1 3 3 3 0 HsdM N-terminal domain ketoacyl-synt PF00109.26 KIK33718.1 - 4.4e-21 75.6 1.5 4.7e-21 75.5 1.5 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 KIK33718.1 - 3e-05 23.5 0.1 3e-05 23.5 0.1 1.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain Nucleoporin_C PF03177.14 KIK33719.1 - 6.5e-32 111.0 0.0 6.8e-31 107.7 0.0 2.0 1 1 1 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KIK33719.1 - 2.9e-30 105.4 2.8 6.6e-29 100.9 1.5 2.3 1 1 0 2 2 2 2 Nup133 N terminal like Tim29 PF10171.9 KIK33720.1 - 0.028 13.9 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 Alpha_L_fucos PF01120.17 KIK33722.1 - 9e-79 265.4 4.5 1.2e-78 265.0 4.5 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase GHL6 PF14871.6 KIK33722.1 - 0.033 14.4 0.0 0.078 13.1 0.0 1.6 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 CHAT PF12770.7 KIK33724.1 - 3.9e-09 36.3 0.0 4.3e-09 36.2 0.0 1.0 1 0 0 1 1 1 1 CHAT domain Peptidase_M20 PF01546.28 KIK33724.1 - 0.028 14.1 0.0 0.031 14.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 MMR_HSR1 PF01926.23 KIK33725.1 - 6.2e-06 26.3 0.0 1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK33725.1 - 0.00015 21.7 0.2 0.0072 16.3 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase G-alpha PF00503.20 KIK33725.1 - 0.0027 16.9 0.4 0.68 9.0 0.1 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KIK33725.1 - 0.0031 17.7 0.0 0.1 12.9 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KIK33725.1 - 0.011 15.6 0.2 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KIK33725.1 - 0.013 15.9 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 KIK33725.1 - 0.043 13.6 0.0 7.8 6.2 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.6 KIK33725.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 KIK33725.1 - 0.069 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Septin Pkinase_Tyr PF07714.17 KIK33726.1 - 1.5e-17 63.8 0.0 1.6e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK33726.1 - 5.3e-12 45.6 0.0 5.8e-12 45.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK33726.1 - 5.1e-05 22.7 0.0 6.2e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIK33726.1 - 0.0092 15.6 0.0 0.0095 15.5 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KIK33726.1 - 0.03 13.1 0.1 0.032 13.0 0.1 1.0 1 0 0 1 1 1 0 Fungal protein kinase Ank_2 PF12796.7 KIK33727.1 - 1.1e-17 64.4 1.2 3.3e-09 37.2 0.0 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK33727.1 - 1.5e-08 35.0 0.3 4.1e-08 33.6 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIK33727.1 - 2.6e-08 34.0 1.1 4.5e-07 30.0 0.1 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KIK33727.1 - 4.5e-07 30.0 0.3 0.0032 17.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KIK33727.1 - 9.5e-07 28.7 0.2 0.023 15.2 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat AAA_33 PF13671.6 KIK33728.1 - 0.0089 16.2 1.1 1.4 9.0 0.7 2.4 2 0 0 2 2 2 2 AAA domain LRR_4 PF12799.7 KIK33729.1 - 0.005 17.2 3.5 10 6.7 0.1 5.1 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KIK33730.1 - 1.7e-07 31.0 0.0 2.2e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK33730.1 - 0.017 15.0 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 F-box domain WD40 PF00400.32 KIK33731.1 - 2.5e-59 195.8 29.8 1.1e-05 26.0 0.5 12.1 12 0 0 12 12 12 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33731.1 - 2e-11 44.0 4.1 0.59 10.5 0.0 8.2 2 2 7 10 10 10 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK33731.1 - 1.4e-06 27.6 4.8 1.1 8.2 0.1 6.7 4 2 2 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 KIK33731.1 - 2.4e-05 24.0 0.0 22 5.2 0.0 6.3 6 0 0 6 6 6 1 PQQ enzyme repeat GSDH PF07995.11 KIK33731.1 - 6.8e-05 22.3 0.0 0.48 9.7 0.0 3.4 3 0 0 3 3 3 2 Glucose / Sorbosone dehydrogenase Nup160 PF11715.8 KIK33731.1 - 9.7e-05 21.2 0.2 0.23 10.0 0.0 2.8 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK33731.1 - 0.027 13.8 0.1 31 3.8 0.0 3.8 4 0 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.6 KIK33731.1 - 0.5 9.9 8.8 12 5.4 1.3 4.5 2 1 1 3 3 3 0 PQQ-like domain Metallophos PF00149.28 KIK33734.1 - 4e-12 47.1 1.0 4.8e-12 46.8 0.1 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF4218 PF13960.6 KIK33735.1 - 0.00083 18.9 0.1 0.0014 18.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) TRI5 PF06330.11 KIK33735.1 - 0.0038 16.2 0.4 0.0047 15.8 0.4 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Transposase_21 PF02992.14 KIK33736.1 - 9.7e-07 28.2 0.3 4.4e-06 26.1 0.1 2.1 2 0 0 2 2 2 1 Transposase family tnp2 DDE_1 PF03184.19 KIK33737.1 - 0.0013 18.4 0.1 0.0018 18.0 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Alpha_kinase PF02816.18 KIK33742.1 - 3.2e-12 46.9 0.0 4.1e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family HTH_21 PF13276.6 KIK33744.1 - 0.00025 21.1 0.4 0.00096 19.2 0.3 2.1 2 1 0 2 2 2 1 HTH-like domain Arg_repressor PF01316.21 KIK33744.1 - 0.015 15.0 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain HTH_Tnp_Tc3_2 PF01498.18 KIK33744.1 - 0.022 15.0 0.2 0.043 14.1 0.1 1.5 1 1 0 1 1 1 0 Transposase Sigma54_DBD PF04552.13 KIK33744.1 - 0.039 13.6 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54, DNA binding domain Rxt3 PF08642.10 KIK33745.1 - 1.6e-05 25.6 0.0 0.001 19.8 0.1 2.3 1 1 1 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 KIK33745.1 - 0.064 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 LCCL domain Methyltransf_23 PF13489.6 KIK33746.1 - 3.2e-09 36.8 0.0 4.2e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK33746.1 - 0.00026 21.6 0.0 0.0005 20.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK33746.1 - 0.00087 19.9 0.0 0.0015 19.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK33746.1 - 0.009 16.7 0.0 0.019 15.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KIK33746.1 - 0.01 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.6 KIK33746.1 - 0.071 12.9 0.0 1 9.1 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 KIK33746.1 - 0.086 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain zf-C2H2_2 PF12756.7 KIK33747.1 - 0.0054 17.1 1.3 0.012 16.0 1.3 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KIK33747.1 - 1 10.4 3.7 22 6.2 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger DDE_Tnp_4 PF13359.6 KIK33750.1 - 5.9e-13 48.8 0.0 6.8e-11 42.1 0.0 2.0 2 0 0 2 2 2 2 DDE superfamily endonuclease APG12 PF04110.13 KIK33758.1 - 1.9e-30 105.1 0.0 2.3e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KIK33758.1 - 0.011 15.9 0.0 0.014 15.6 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like PGI PF00342.19 KIK33760.1 - 9.3e-235 779.8 0.2 1.1e-234 779.5 0.2 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF2750 PF11042.8 KIK33766.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2750) MMR_HSR1 PF01926.23 KIK33767.1 - 1.8e-08 34.4 0.0 2.7e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK33767.1 - 0.0082 16.1 0.1 0.02 14.8 0.1 1.6 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 KIK33767.1 - 0.011 15.8 0.3 1.8 8.6 0.0 2.6 1 1 2 3 3 3 0 Dynamin family IIGP PF05049.13 KIK33767.1 - 0.041 13.0 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 KIK33767.1 - 0.15 12.6 0.7 0.24 11.9 0.7 1.7 1 1 0 1 1 1 0 ABC transporter AIG1 PF04548.16 KIK33767.1 - 0.18 11.1 0.0 0.26 10.6 0.0 1.4 1 1 0 1 1 1 0 AIG1 family Zn_clus PF00172.18 KIK33768.1 - 0.27 11.4 9.5 0.62 10.2 1.5 2.3 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5487 PF17589.2 KIK33769.1 - 0.11 12.7 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5487) RVT_1 PF00078.27 KIK33770.1 - 0.16 11.5 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) CHAT PF12770.7 KIK33775.1 - 3.2e-30 105.6 0.0 7.2e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK33775.1 - 5.3e-12 45.2 16.6 0.0023 17.8 0.0 8.1 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIK33775.1 - 2.8e-08 33.9 15.3 0.22 11.8 0.2 8.3 5 2 2 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK33775.1 - 4.4e-08 32.6 10.5 0.98 9.7 0.1 9.3 9 1 1 10 10 10 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK33775.1 - 5.7e-07 29.8 14.9 13 7.0 0.0 9.6 9 1 1 10 10 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK33775.1 - 9.7e-07 28.5 0.6 11 6.6 0.0 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK33775.1 - 1.4e-05 24.7 9.1 7.7 6.5 0.1 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK33775.1 - 0.00013 21.8 5.5 22 5.4 0.0 6.6 6 1 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 KIK33775.1 - 0.0037 17.3 1.2 12 6.0 0.1 5.2 5 0 0 5 5 5 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 KIK33775.1 - 0.037 14.7 5.9 44 5.0 0.0 7.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK33775.1 - 0.044 14.3 6.3 35 5.0 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat PilJ PF13675.6 KIK33775.1 - 0.092 12.8 5.8 0.41 10.7 0.4 4.1 4 1 1 5 5 5 0 Type IV pili methyl-accepting chemotaxis transducer N-term TPR_11 PF13414.6 KIK33775.1 - 0.093 12.4 1.2 97 2.8 0.0 5.1 6 0 0 6 6 6 0 TPR repeat Zeta_toxin PF06414.12 KIK33775.1 - 0.14 11.4 0.3 0.63 9.3 0.1 2.1 2 0 0 2 2 2 0 Zeta toxin TPR_10 PF13374.6 KIK33777.1 - 7.8e-16 57.4 13.4 0.0023 17.7 0.0 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat CHAT PF12770.7 KIK33777.1 - 1.7e-15 57.2 0.1 3.4e-15 56.2 0.1 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 KIK33777.1 - 3.4e-11 43.3 15.2 0.31 11.3 0.2 8.4 3 2 5 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 KIK33777.1 - 5.5e-09 35.5 7.6 5.6 7.0 0.0 9.1 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK33777.1 - 2.4e-07 30.3 3.6 8.7 6.6 0.0 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK33777.1 - 3.5e-07 29.8 15.7 22 5.5 0.0 10.3 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK33777.1 - 1.8e-05 24.6 0.1 18 5.8 0.0 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK33777.1 - 3.3e-05 24.3 21.6 4.6 8.3 0.0 10.6 10 2 2 12 12 12 1 Tetratricopeptide repeat MIT PF04212.18 KIK33777.1 - 0.00063 19.8 0.2 2 8.5 0.1 5.3 5 0 0 5 5 5 1 MIT (microtubule interacting and transport) domain Vta1_C PF18097.1 KIK33777.1 - 0.0069 16.1 14.7 0.78 9.5 0.1 6.1 6 0 0 6 6 6 1 Vta1 C-terminal domain TPR_11 PF13414.6 KIK33777.1 - 0.019 14.6 0.1 57 3.5 0.0 5.3 7 0 0 7 7 7 0 TPR repeat DUF4164 PF13747.6 KIK33777.1 - 3.7 7.9 5.2 6.8 7.0 0.2 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4164) DUF3328 PF11807.8 KIK33779.1 - 1.9e-18 67.0 0.9 1.8e-17 63.9 0.7 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) PAS_3 PF08447.12 KIK33780.1 - 0.02 15.2 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 PAS fold PRRSV_2b PF07069.11 KIK33780.1 - 0.39 11.3 0.9 43 4.7 0.0 2.8 1 1 2 3 3 3 0 Porcine reproductive and respiratory syndrome virus 2b PH PF00169.29 KIK33782.1 - 0.00097 19.6 0.4 0.0038 17.7 0.0 2.2 2 0 0 2 2 2 1 PH domain Exo_endo_phos PF03372.23 KIK33783.1 - 0.001 18.6 0.0 0.0017 17.9 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C2HE PF16278.5 KIK33786.1 - 0.076 13.5 1.0 0.23 11.9 1.0 1.9 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger MttA_Hcf106 PF02416.16 KIK33787.1 - 0.054 12.8 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 mttA/Hcf106 family Plavaka PF18759.1 KIK33789.1 - 4.1e-16 59.1 0.0 5.9e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase WWamide PF08258.11 KIK33789.1 - 0.82 10.2 7.8 2 9.0 3.3 2.9 2 0 0 2 2 2 0 WWamide peptide zf-MYND PF01753.18 KIK33790.1 - 0.0009 19.3 22.1 0.0013 18.8 22.1 1.2 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.7 KIK33792.1 - 0.29 12.3 6.3 0.81 10.8 6.3 1.8 1 1 0 1 1 1 0 ECL1/2/3 zinc binding proteins WD40 PF00400.32 KIK33793.1 - 9.4e-23 80.1 10.7 2.5e-08 34.4 3.1 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33793.1 - 2.7e-12 46.8 1.0 0.00025 21.3 0.2 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK33793.1 - 4.6e-07 28.9 0.2 0.11 11.1 0.0 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK33793.1 - 0.00018 21.0 0.0 0.0062 15.9 0.0 2.4 1 1 1 2 2 2 1 WD40-like domain Phage_Mu_Gp45 PF06890.12 KIK33793.1 - 0.004 16.9 0.0 5.4 6.8 0.0 3.0 2 1 1 3 3 3 2 Bacteriophage Mu Gp45 protein PQQ PF01011.21 KIK33793.1 - 0.0051 16.7 0.1 1.3 9.0 0.0 2.7 3 0 0 3 3 3 1 PQQ enzyme repeat Ge1_WD40 PF16529.5 KIK33793.1 - 0.037 13.0 0.0 0.14 11.0 0.0 1.9 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KIK33793.1 - 0.2 9.9 0.0 0.38 9.0 0.0 1.4 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 KIK33794.1 - 7.2e-18 64.6 8.4 1.1e-05 26.0 0.1 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33794.1 - 2.1e-08 34.3 0.2 0.052 13.8 0.0 3.4 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KIK33794.1 - 0.00034 19.2 0.0 0.00088 17.9 0.0 1.5 1 1 1 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.12 KIK33794.1 - 0.013 15.4 0.0 9.3 6.3 0.2 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 KIK33794.1 - 0.054 14.0 0.3 21 5.8 0.0 2.7 3 0 0 3 3 3 0 PQQ-like domain Ge1_WD40 PF16529.5 KIK33794.1 - 0.06 12.3 0.2 1.9 7.4 0.1 2.3 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 KIK33794.1 - 0.097 11.7 0.2 0.16 11.0 0.0 1.4 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain RCC1_2 PF13540.6 KIK33794.1 - 0.14 12.0 1.1 10 6.1 0.1 3.0 2 1 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat 4HB PF17947.1 KIK33795.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Four helical bundle domain p450 PF00067.22 KIK33796.1 - 2.7e-67 227.5 0.0 3.6e-67 227.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YwcE PF17368.2 KIK33799.1 - 0.006 17.2 1.0 0.0064 17.1 1.0 1.1 1 0 0 1 1 1 1 Spore morphogenesis and germination YwcE Gemini_mov PF01708.16 KIK33799.1 - 0.016 14.9 0.4 0.018 14.8 0.4 1.1 1 0 0 1 1 1 0 Geminivirus putative movement protein AA_kinase PF00696.28 KIK33801.1 - 0.15 11.7 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Amino acid kinase family WD40 PF00400.32 KIK33803.1 - 1.6e-29 101.5 11.3 1.6e-08 35.1 1.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33803.1 - 4.7e-08 33.2 1.6 0.096 13.0 0.0 4.4 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK33803.1 - 2.5e-06 26.4 0.1 0.018 13.7 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK33803.1 - 0.0014 17.7 0.3 0.26 10.2 0.0 2.6 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK33803.1 - 0.0052 16.2 0.0 0.63 9.3 0.0 3.1 3 1 1 4 4 4 1 WD40-like domain PD40 PF07676.12 KIK33803.1 - 0.066 13.2 0.0 5.4 7.1 0.0 3.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat UvrD_C_2 PF13538.6 KIK33809.1 - 2.5e-06 27.2 0.0 3.9e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 KIK33809.1 - 0.00028 19.0 0.0 0.00029 18.9 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C PF13361.6 KIK33809.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Cupin_8 PF13621.6 KIK33810.1 - 0.0034 17.1 0.0 0.0068 16.2 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KIK33810.1 - 0.055 12.9 0.1 0.12 11.9 0.1 1.6 1 1 0 1 1 1 0 Cupin superfamily protein Macoilin PF09726.9 KIK33811.1 - 2.4 6.6 8.1 2.8 6.4 8.1 1.1 1 0 0 1 1 1 0 Macoilin family BRD4_CDT PF17105.5 KIK33811.1 - 4.3 7.0 14.5 1.7 8.3 8.6 2.5 3 0 0 3 3 3 0 C-terminal domain of bromodomain protein 4 SOG2 PF10428.9 KIK33811.1 - 8.3 5.5 16.2 9.5 5.3 16.2 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 KIK33811.1 - 8.8 6.1 16.2 10 5.9 16.2 1.1 1 0 0 1 1 1 0 SPX domain Flavodoxin_3 PF12641.7 KIK33812.1 - 0.028 14.1 0.0 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 Flavodoxin domain PAP2 PF01569.21 KIK33814.1 - 2.1e-19 69.7 0.4 2.1e-19 69.7 0.4 2.0 2 1 0 2 2 2 1 PAP2 superfamily TspO_MBR PF03073.15 KIK33814.1 - 0.0076 16.3 0.7 0.016 15.3 0.7 1.5 1 0 0 1 1 1 1 TspO/MBR family DUF2070 PF09843.9 KIK33814.1 - 0.03 12.6 1.8 0.039 12.2 1.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SurA_N_3 PF13624.6 KIK33814.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 SurA N-terminal domain KH_1 PF00013.29 KIK33815.1 - 1.5e-07 31.2 1.8 0.0045 16.8 0.1 3.2 3 0 0 3 3 3 2 KH domain p450 PF00067.22 KIK33815.1 - 0.01 14.6 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 0 Cytochrome P450 ERCC4 PF02732.15 KIK33817.1 - 7.5e-22 78.2 0.0 2.7e-21 76.4 0.0 2.0 2 0 0 2 2 2 1 ERCC4 domain DUF1340 PF07067.11 KIK33817.1 - 0.03 13.7 0.1 0.1 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1340) DNA_repr_REX1B PF14966.6 KIK33817.1 - 0.085 13.5 0.1 0.22 12.2 0.1 1.7 1 0 0 1 1 1 0 DNA repair REX1-B FTCD_C PF04961.12 KIK33817.1 - 0.17 11.6 0.0 0.43 10.3 0.0 1.6 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase CPSase_L_D2 PF02786.17 KIK33820.1 - 2.8e-68 229.6 0.0 4.1e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.6 KIK33820.1 - 0.0015 18.2 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 KIK33820.1 - 0.0026 17.3 0.0 0.0064 16.1 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus SpoOE-like PF09388.10 KIK33820.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein Pox_TAP PF03355.14 KIK33821.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Viral Trans-Activator Protein TPR_14 PF13428.6 KIK33824.1 - 0.0018 18.9 0.3 3.4 8.7 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK33824.1 - 0.012 16.0 0.3 6.7 7.3 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIK33824.1 - 0.014 15.7 0.3 2.5 8.5 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat CHAT PF12770.7 KIK33825.1 - 1.4e-29 103.4 0.1 1.8e-29 103.1 0.1 1.0 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK33826.1 - 4.6e-11 42.2 0.9 4.8e-05 23.1 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK33826.1 - 8.6e-08 32.4 0.7 0.0017 18.6 0.2 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK33826.1 - 0.011 15.5 1.0 0.33 10.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIK33826.1 - 0.012 15.9 0.0 1.9 9.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK33826.1 - 0.071 14.0 1.0 1.3 10.1 0.1 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK33826.1 - 0.16 12.2 1.1 10 6.6 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK33826.1 - 0.18 11.9 2.1 2.3 8.5 1.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK33826.1 - 0.2 11.4 0.5 2.1 8.1 0.0 2.5 3 0 0 3 3 3 0 TPR repeat TPR_12 PF13424.6 KIK33827.1 - 0.00051 20.3 0.7 0.064 13.6 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK33827.1 - 0.16 11.7 0.1 1.9 8.3 0.0 2.7 3 1 0 3 3 3 0 TPR repeat CxC3 PF18804.1 KIK33832.1 - 0.036 13.9 0.0 0.041 13.7 0.0 1.0 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases RXT2_N PF08595.11 KIK33833.1 - 0.011 15.8 2.7 0.021 14.8 2.7 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal TT_ORF2 PF02957.15 KIK33833.1 - 0.021 15.7 2.1 0.021 15.7 2.1 2.0 2 0 0 2 2 2 0 TT viral ORF2 NOA36 PF06524.12 KIK33833.1 - 0.05 12.9 5.2 0.07 12.4 5.2 1.2 1 0 0 1 1 1 0 NOA36 protein PGA2 PF07543.12 KIK33833.1 - 2 8.4 6.5 4.1 7.4 6.5 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 Cwf_Cwc_15 PF04889.12 KIK33833.1 - 2.3 7.9 10.3 4.1 7.1 10.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pox_Ag35 PF03286.14 KIK33833.1 - 3.1 7.6 7.0 5.4 6.8 7.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TFIIF_alpha PF05793.12 KIK33833.1 - 3.5 6.1 14.4 5.4 5.5 14.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TLD PF07534.16 KIK33836.1 - 4e-28 98.4 0.0 4.6e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 TLD HET PF06985.11 KIK33837.1 - 8e-25 87.9 0.0 1.5e-24 87.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SSPI PF14098.6 KIK33837.1 - 0.14 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Small, acid-soluble spore protein I DNA_pol_phi PF04931.13 KIK33841.1 - 3.9 5.5 18.4 2.9 5.9 16.4 1.7 2 0 0 2 2 2 0 DNA polymerase phi SDA1 PF05285.12 KIK33841.1 - 4.2 6.7 9.0 6.9 6.0 9.0 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KIK33841.1 - 5.1 5.3 6.1 9.1 4.4 6.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KIK33841.1 - 5.6 5.0 10.7 8.6 4.4 10.7 1.2 1 0 0 1 1 1 0 Nop14-like family Aldo_ket_red PF00248.21 KIK33843.1 - 4.3e-50 170.6 0.0 4.1e-49 167.3 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family TPP_enzyme_N PF02776.18 KIK33844.1 - 1.1e-37 129.2 0.8 2.1e-37 128.4 0.4 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KIK33844.1 - 9.2e-16 58.0 0.1 2.2e-15 56.7 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KIK33844.1 - 8.4e-07 28.8 0.0 2.3e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Cu-oxidase PF00394.22 KIK33845.1 - 2.9e-40 138.0 0.1 8.8e-38 129.9 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK33845.1 - 8.6e-37 125.9 4.6 5.6e-36 123.3 0.0 2.8 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK33845.1 - 2.4e-35 121.1 0.6 8.4e-35 119.4 0.3 2.2 2 0 0 2 2 2 1 Multicopper oxidase zf-CCHC PF00098.23 KIK33851.1 - 0.0073 16.3 6.0 0.014 15.4 6.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 KIK33851.1 - 0.41 10.4 5.3 0.25 11.1 3.0 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 KIK33851.1 - 0.97 9.3 4.3 1.4 8.8 4.3 1.2 1 0 0 1 1 1 0 Zinc knuckle CLIP1_ZNF PF16641.5 KIK33851.1 - 1.7 8.6 5.6 2.6 8.0 5.6 1.3 1 0 0 1 1 1 0 CLIP1 zinc knuckle KDZ PF18758.1 KIK33852.1 - 4.7e-66 222.6 0.1 1.2e-65 221.3 0.0 1.6 1 1 1 2 2 2 1 Kyakuja-Dileera-Zisupton transposase IRF PF00605.17 KIK33852.1 - 0.064 13.6 0.4 15 5.9 0.1 2.5 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor DUF5413 PF17434.2 KIK33852.1 - 0.22 11.9 0.0 0.46 10.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5413) PMT PF02366.18 KIK33852.1 - 0.23 11.0 0.2 0.92 9.0 0.0 1.9 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase KDZ PF18758.1 KIK33856.1 - 2e-64 217.3 0.0 3.3e-64 216.6 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK33856.1 - 2.1e-44 150.1 0.1 5.5e-44 148.7 0.1 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK33856.1 - 9e-06 25.8 0.0 2.8e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK33856.1 - 0.0026 17.6 0.1 0.0087 15.9 0.1 1.9 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases Glyco_hydro_85 PF03644.13 KIK33858.1 - 8.1e-62 209.4 0.0 1e-61 209.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Suf PF05843.14 KIK33860.1 - 2.4e-75 254.3 0.2 1.4e-73 248.5 0.0 3.1 3 1 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KIK33860.1 - 4.7e-09 36.6 0.0 0.38 11.3 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK33860.1 - 9e-06 26.1 10.4 0.53 11.3 0.0 6.8 6 1 2 8 8 8 2 Tetratricopeptide repeat FTCD_C PF04961.12 KIK33860.1 - 0.0076 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase NRDE-2 PF08424.10 KIK33860.1 - 0.022 13.9 6.8 0.14 11.3 0.7 4.3 3 2 1 4 4 4 0 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 KIK33860.1 - 0.27 12.0 6.0 3.7 8.4 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Cytochrom_B562 PF07361.11 KIK33860.1 - 0.45 11.2 1.7 29 5.4 0.0 3.9 4 1 0 4 4 4 0 Cytochrome b562 LIM_bind PF01803.16 KIK33861.1 - 0.11 12.0 0.5 0.19 11.3 0.5 1.3 1 0 0 1 1 1 0 LIM-domain binding protein Mab-21 PF03281.14 KIK33862.1 - 0.14 11.4 0.7 0.18 11.1 0.7 1.0 1 0 0 1 1 1 0 Mab-21 protein Pkinase PF00069.25 KIK33864.1 - 1.4e-58 198.4 0.0 2.1e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK33864.1 - 3.3e-31 108.5 0.0 4.5e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK33864.1 - 7.7e-07 28.7 0.0 1.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIK33864.1 - 0.028 13.4 0.0 0.18 10.7 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 KIK33864.1 - 0.092 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 KIK33865.1 - 3.6e-21 75.1 10.1 9.7e-06 26.2 0.2 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33865.1 - 0.00062 20.0 0.1 1.9 8.9 0.0 3.0 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain ubiquitin PF00240.23 KIK33866.1 - 1.3e-05 24.8 0.0 2.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KIK33866.1 - 0.045 13.6 0.1 0.08 12.8 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like p450 PF00067.22 KIK33867.1 - 8.1e-65 219.3 0.0 9.9e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 4HBT_2 PF13279.6 KIK33868.1 - 2.5e-14 53.8 0.0 3.5e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KIK33868.1 - 6.8e-07 29.5 0.0 1.4e-06 28.5 0.0 1.5 1 1 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 KIK33868.1 - 0.036 13.3 0.0 0.57 9.4 0.1 2.0 2 0 0 2 2 2 0 Acyl-ACP thioesterase F-box-like PF12937.7 KIK33869.1 - 0.00043 20.1 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like Lipase_3 PF01764.25 KIK33870.1 - 2.2e-21 76.2 0.0 3.3e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIK33870.1 - 0.0095 16.6 0.1 0.012 16.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK33870.1 - 0.024 13.9 0.1 0.038 13.3 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK33870.1 - 0.044 13.4 0.0 0.091 12.4 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipase3_N PF03893.16 KIK33870.1 - 0.09 12.8 0.7 0.18 11.9 0.7 1.5 1 0 0 1 1 1 0 Lipase 3 N-terminal region DUF4386 PF14329.6 KIK33870.1 - 0.12 12.2 2.2 0.2 11.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) Plavaka PF18759.1 KIK33873.1 - 2.5e-11 43.4 0.0 2.6e-09 36.8 0.0 2.3 1 1 1 2 2 2 2 Plavaka transposase WD40 PF00400.32 KIK33874.1 - 4.1e-31 106.5 11.6 8.6e-08 32.7 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33874.1 - 7.5e-07 29.4 0.3 0.014 15.7 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK33874.1 - 6.6e-05 21.7 0.0 0.022 13.4 0.0 2.6 3 0 0 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.12 KIK33874.1 - 0.00038 20.3 1.4 1.1 9.3 0.3 3.6 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK33874.1 - 0.00061 18.8 0.0 0.8 8.6 0.0 2.6 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 KIK33874.1 - 0.0043 16.2 0.0 1.1 8.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1513) WD40_like PF17005.5 KIK33874.1 - 0.12 11.7 0.0 2.5 7.3 0.0 2.7 3 0 0 3 3 3 0 WD40-like domain HSP20 PF00011.21 KIK33878.1 - 1.2e-23 83.1 0.1 2e-23 82.5 0.1 1.4 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIK33878.1 - 1e-10 41.0 0.0 1.7e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF4097 PF13349.6 KIK33878.1 - 0.0075 15.6 0.2 0.0091 15.4 0.2 1.1 1 0 0 1 1 1 1 Putative adhesin CS PF04969.16 KIK33878.1 - 0.014 16.4 0.1 0.022 15.7 0.1 1.4 1 1 0 1 1 1 0 CS domain BON PF04972.17 KIK33878.1 - 0.16 12.3 0.4 0.58 10.5 0.1 1.9 2 0 0 2 2 2 0 BON domain F-box-like PF12937.7 KIK33879.1 - 9.8e-11 41.4 1.8 2.3e-10 40.2 1.8 1.7 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK33879.1 - 0.012 15.5 1.7 0.88 9.5 0.7 2.5 2 0 0 2 2 2 0 F-box domain F-box-like_2 PF13013.6 KIK33879.1 - 0.096 12.7 0.5 0.66 10.0 0.5 2.1 1 1 0 1 1 1 0 F-box-like domain Helicase_C PF00271.31 KIK33881.1 - 3.8e-10 40.1 0.0 1.5e-09 38.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK33881.1 - 3.6e-09 36.6 0.0 1.1e-08 35.0 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIK33881.1 - 0.00078 19.5 0.0 0.003 17.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit WD40 PF00400.32 KIK33883.1 - 1.3e-37 127.1 20.2 5.2e-07 30.2 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK33883.1 - 5.5e-13 49.0 0.2 0.033 14.5 0.0 4.5 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WW PF00397.26 KIK33883.1 - 7e-06 26.0 0.5 7e-06 26.0 0.5 2.7 2 0 0 2 2 2 1 WW domain Nup160 PF11715.8 KIK33883.1 - 3.9e-05 22.5 0.0 0.29 9.7 0.0 3.6 3 0 0 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KIK33883.1 - 0.049 12.4 0.1 6.5 5.4 0.0 3.6 2 1 1 3 3 3 0 Nup133 N terminal like WD40_like PF17005.5 KIK33883.1 - 0.15 11.3 0.0 4.6 6.5 0.0 2.9 3 1 1 4 4 4 0 WD40-like domain F-box-like PF12937.7 KIK33890.1 - 0.00038 20.3 0.1 0.00086 19.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK33890.1 - 0.0053 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KIK33890.1 - 0.057 13.3 0.3 0.45 10.4 0.1 2.3 2 0 0 2 2 2 0 F-box Amidohydro_3 PF07969.11 KIK33891.1 - 2e-07 30.9 3.9 0.00015 21.4 0.1 3.8 4 0 0 4 4 4 2 Amidohydrolase family Amidohydro_1 PF01979.20 KIK33891.1 - 3.9e-07 29.7 0.1 1.4e-05 24.5 0.1 2.9 2 1 0 2 2 2 1 Amidohydrolase family Pkinase PF00069.25 KIK33894.1 - 5e-37 127.7 0.0 5.7e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK33894.1 - 3.8e-20 72.3 0.0 5.9e-20 71.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK33894.1 - 7.9e-06 24.9 0.0 1.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIK33894.1 - 3.7e-05 23.2 0.0 4.6e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK33894.1 - 0.00068 19.6 0.0 0.0032 17.4 0.0 1.8 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK33894.1 - 0.028 13.4 0.0 0.036 13.0 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KIK33894.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-C2H2_aberr PF17017.5 KIK33896.1 - 0.0048 17.1 0.6 0.0055 16.9 0.6 1.1 1 0 0 1 1 1 1 Aberrant zinc-finger FOXP-CC PF16159.5 KIK33896.1 - 0.0092 16.6 0.1 0.011 16.4 0.1 1.1 1 0 0 1 1 1 1 FOXP coiled-coil domain Plavaka PF18759.1 KIK33897.1 - 3.5e-123 411.0 0.0 4.7e-123 410.5 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Oxidored_FMN PF00724.20 KIK33899.1 - 1.1e-07 31.5 0.0 1.1e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PHD_4 PF16866.5 KIK33900.1 - 0.014 15.5 3.6 0.018 15.1 1.7 2.2 2 1 0 2 2 2 0 PHD-finger zf-Di19 PF05605.12 KIK33900.1 - 0.23 11.8 0.1 0.23 11.8 0.1 3.0 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding PHD PF00628.29 KIK33900.1 - 1.5 8.8 4.6 1 9.3 0.5 2.7 3 0 0 3 3 3 0 PHD-finger DNMT1-RFD PF12047.8 KIK33904.1 - 1.5e-11 44.6 0.4 1e-10 41.8 0.4 2.0 1 1 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain K_oxygenase PF13434.6 KIK33906.1 - 0.23 10.5 0.1 0.27 10.4 0.1 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF4780 PF16012.5 KIK33907.1 - 0.11 11.9 0.2 6.2 6.3 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4780) GFRP PF06399.13 KIK33908.1 - 0.096 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) DUF1806 PF08830.10 KIK33909.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1806) Defensin_RK-1 PF17860.1 KIK33911.1 - 0.018 15.5 0.9 0.031 14.7 0.9 1.4 1 0 0 1 1 1 0 RK-1-like defensin PIF1 PF05970.14 KIK33912.1 - 0.017 14.3 0.4 0.02 14.0 0.4 1.1 1 0 0 1 1 1 0 PIF1-like helicase Helitron_like_N PF14214.6 KIK33914.1 - 7.5e-14 52.4 0.8 4.6e-13 49.8 0.0 2.3 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus DUF362 PF04015.12 KIK33914.1 - 0.15 12.2 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF362) Helitron_like_N PF14214.6 KIK33915.1 - 3.8e-09 37.0 0.0 4.4e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Transket_pyr PF02779.24 KIK33916.1 - 4.5e-61 205.6 0.0 6.9e-61 205.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KIK33916.1 - 2.1e-45 154.9 0.0 3.6e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KIK33916.1 - 5.9e-44 149.4 0.0 9.3e-44 148.8 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal Cyto_heme_lyase PF01265.17 KIK33920.1 - 2.2e-61 208.0 1.9 1.2e-36 126.8 0.6 2.3 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase Cu-oxidase_2 PF07731.14 KIK33922.1 - 0.11 12.3 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Multicopper oxidase Plavaka PF18759.1 KIK33927.1 - 2.7e-54 184.6 1.2 1.8e-39 135.9 0.0 2.2 1 1 1 2 2 2 2 Plavaka transposase Pkinase_fungal PF17667.1 KIK33928.1 - 2.7e-42 145.0 0.0 8.1e-22 77.6 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIK33928.1 - 2.6e-05 23.7 0.0 4.8e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK33928.1 - 0.00023 21.1 0.2 0.00037 20.5 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK33928.1 - 0.00082 19.0 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pro_isomerase PF00160.21 KIK33933.1 - 5.3e-47 160.0 0.2 6e-47 159.8 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S25 PF03297.15 KIK33934.1 - 4.2e-39 132.8 0.7 4.6e-39 132.7 0.7 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 KIK33934.1 - 0.0036 16.8 0.6 0.0057 16.2 0.6 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 KIK33934.1 - 0.0082 16.1 0.1 0.011 15.6 0.1 1.2 1 0 0 1 1 1 1 MarR family MerR PF00376.23 KIK33934.1 - 0.045 13.5 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 MerR family regulatory protein GntR PF00392.21 KIK33934.1 - 0.099 12.3 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family PRKCSH-like PF12999.7 KIK33935.1 - 4.8e-49 166.5 3.1 5.2e-49 166.4 2.0 1.6 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KIK33935.1 - 8.5e-26 90.5 0.0 1.6e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KIK33935.1 - 1.3e-11 45.4 0.6 3.4e-11 44.0 0.6 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 KIK33935.1 - 0.48 10.7 19.2 0.63 10.3 2.7 2.7 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A DUF3796 PF12676.7 KIK33936.1 - 0.25 11.8 3.1 0.35 11.3 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) Thioesterase PF00975.20 KIK33937.1 - 3.6e-30 105.8 0.0 1.2e-28 100.8 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 KIK33937.1 - 2e-07 31.2 0.0 3.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 KIK33937.1 - 0.00016 22.3 0.1 0.0002 22.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK33937.1 - 0.0099 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KIK33937.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold PE-PPE PF08237.11 KIK33937.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain AMP-binding PF00501.28 KIK33939.1 - 1e-60 205.5 0.0 1.3e-60 205.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 KIK33939.1 - 2.4e-30 106.4 0.0 2e-29 103.4 0.0 2.2 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 KIK33939.1 - 6.4e-09 36.0 0.0 3.9e-08 33.5 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 KIK33939.1 - 0.00046 20.9 0.0 0.0015 19.1 0.0 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK33939.1 - 0.013 14.7 0.0 0.047 12.9 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 MRF_C1 PF13887.6 KIK33939.1 - 0.68 9.1 1.9 0.63 9.3 0.2 1.9 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 AMP-binding PF00501.28 KIK33942.1 - 2.2e-61 207.7 0.0 3.2e-61 207.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme VanW PF04294.13 KIK33945.1 - 0.16 11.7 0.4 0.39 10.4 0.2 1.7 2 0 0 2 2 2 0 VanW like protein GARP PF16731.5 KIK33948.1 - 0.025 14.3 0.7 0.025 14.3 0.7 1.5 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma SPX PF03105.19 KIK33949.1 - 4.2 7.2 6.9 6 6.7 6.9 1.1 1 0 0 1 1 1 0 SPX domain Pyr_redox_3 PF13738.6 KIK33950.1 - 4.9e-24 85.1 0.0 2.1e-21 76.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KIK33950.1 - 2.2e-19 69.3 0.0 1.1e-18 67.0 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KIK33950.1 - 7.8e-16 58.1 0.0 2.2e-12 46.8 0.0 2.7 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK33950.1 - 1.5e-11 44.1 0.0 1.1e-07 31.3 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KIK33950.1 - 2.4e-05 23.6 0.1 0.00018 20.7 0.0 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 KIK33950.1 - 2.5e-05 23.7 0.0 0.00091 18.6 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KIK33950.1 - 6.3e-05 23.5 0.0 0.052 14.1 0.0 3.0 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK33950.1 - 0.0001 22.1 0.0 0.12 11.9 0.0 3.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK33950.1 - 0.00024 21.3 0.0 0.0013 18.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIK33950.1 - 0.0012 17.6 0.0 0.0059 15.4 0.0 2.1 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 KIK33950.1 - 0.0016 17.6 0.0 0.0047 16.1 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KIK33950.1 - 0.0075 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KIK33950.1 - 0.044 13.1 0.0 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KIK33950.1 - 0.066 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KIK33950.1 - 0.075 12.9 0.1 7 6.5 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KIK33950.1 - 0.11 12.6 0.0 17 5.5 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Arrestin_N PF00339.29 KIK33951.1 - 9.1e-12 45.3 0.0 2.9e-09 37.1 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KIK33951.1 - 4.1e-07 30.5 2.2 1.2e-05 25.8 2.2 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 KIK33951.1 - 0.00029 20.6 0.0 0.00053 19.7 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like HTH_23 PF13384.6 KIK33954.1 - 4.8e-06 26.2 0.0 5.9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 KIK33954.1 - 0.0019 18.2 0.0 0.0023 17.9 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 KIK33954.1 - 0.0026 17.9 0.0 0.0032 17.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain UPF0175 PF03683.13 KIK33954.1 - 0.0044 16.7 0.0 0.0055 16.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0175) HTH_AraC PF00165.23 KIK33954.1 - 0.012 15.7 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_Tnp_1_2 PF13022.6 KIK33954.1 - 0.047 13.8 0.0 0.053 13.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_7 PF02796.15 KIK33954.1 - 0.061 13.4 0.1 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase CENP-B_N PF04218.13 KIK33954.1 - 0.097 12.3 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain DUF134 PF02001.16 KIK33954.1 - 0.1 13.2 0.0 0.13 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF134 UbiA PF01040.18 KIK33955.1 - 1.8e-25 89.7 1.2 2.1e-25 89.5 1.2 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family YitT_membrane PF02588.15 KIK33955.1 - 0.0057 16.0 2.4 0.01 15.2 2.4 1.3 1 0 0 1 1 1 1 Uncharacterised 5xTM membrane BCR, YitT family COG1284 tRNA-synt_2 PF00152.20 KIK33957.1 - 1.4e-06 27.7 2.5 0.00021 20.5 0.4 2.7 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) GerPC PF10737.9 KIK33960.1 - 0.071 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Spore germination protein GerPC KDZ PF18758.1 KIK33961.1 - 1.4e-50 172.0 0.0 2.4e-50 171.3 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK33961.1 - 8.7e-42 141.6 0.1 1.7e-41 140.7 0.1 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK33961.1 - 0.001 19.2 0.2 0.0025 18.0 0.2 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Cauli_VI PF01693.16 KIK33965.1 - 0.025 14.9 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 Caulimovirus viroplasmin GP3_package PF16677.5 KIK33965.1 - 0.13 12.4 0.4 0.27 11.4 0.4 1.5 1 0 0 1 1 1 0 DNA-packaging protein gp3 KDZ PF18758.1 KIK33966.1 - 9.7e-66 221.6 0.1 1.6e-65 220.9 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK33966.1 - 1.2e-44 150.8 0.0 3e-44 149.6 0.0 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK33966.1 - 8.7e-06 25.8 0.0 2.9e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK33966.1 - 0.0027 17.6 0.0 0.0064 16.3 0.0 1.6 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases HTH_Tnp_4 PF13613.6 KIK33967.1 - 0.00012 21.7 0.1 0.00017 21.2 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DUF150_C PF17384.2 KIK33973.1 - 0.044 13.9 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Ctr PF04145.15 KIK33974.1 - 1e-34 120.3 0.4 1.2e-34 120.1 0.4 1.0 1 0 0 1 1 1 1 Ctr copper transporter family CPBP PF02517.16 KIK33974.1 - 7.3 7.0 10.4 0.84 10.1 2.6 2.5 2 1 1 3 3 3 0 CPBP intramembrane metalloprotease Proteasome PF00227.26 KIK33975.1 - 1.1e-52 178.4 0.1 2.2e-52 177.3 0.1 1.5 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIK33975.1 - 1.6e-13 50.0 0.1 2.9e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SKI PF01202.22 KIK33976.1 - 1e-09 38.7 0.0 2.9e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase AAA_33 PF13671.6 KIK33976.1 - 3.1e-06 27.4 0.0 0.00028 21.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KIK33976.1 - 2.1e-05 25.1 0.0 0.00015 22.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK33976.1 - 0.002 18.5 0.0 0.003 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain dNK PF01712.19 KIK33976.1 - 0.021 14.7 0.0 5.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase RsgA_GTPase PF03193.16 KIK33976.1 - 0.031 14.2 0.1 0.094 12.6 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KIK33976.1 - 0.037 14.3 0.0 0.096 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIK33976.1 - 0.048 14.2 0.2 0.11 13.0 0.2 1.6 1 1 0 1 1 1 0 ABC transporter CbiA PF01656.23 KIK33976.1 - 0.058 13.5 0.1 0.11 12.5 0.1 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KIK33976.1 - 0.073 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KIK33976.1 - 0.085 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KIK33976.1 - 0.093 13.2 0.0 1.1 9.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK33976.1 - 0.097 12.4 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 KIK33976.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase APS_kinase PF01583.20 KIK33976.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Cytidylate_kin2 PF13189.6 KIK33976.1 - 0.17 12.0 0.0 0.57 10.3 0.0 1.9 2 1 0 2 2 2 0 Cytidylate kinase-like family adh_short PF00106.25 KIK33978.1 - 8.8e-16 57.9 0.0 7.7e-12 45.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK33978.1 - 3.4e-06 26.8 0.0 7.6e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK33978.1 - 0.0012 18.8 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK33978.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ank_2 PF12796.7 KIK33985.1 - 1.4e-13 51.3 0.1 1.1e-05 25.9 0.1 4.3 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) NACHT PF05729.12 KIK33985.1 - 8.2e-11 42.1 0.3 4.3e-10 39.8 0.3 2.1 1 1 0 1 1 1 1 NACHT domain Ank_3 PF13606.6 KIK33985.1 - 1.5e-06 28.1 1.3 10 7.1 0.1 6.5 6 0 0 6 6 5 1 Ankyrin repeat AAA_16 PF13191.6 KIK33985.1 - 7e-06 26.5 1.3 3e-05 24.4 0.1 2.6 3 0 0 3 3 3 1 AAA ATPase domain Helo_like_N PF17111.5 KIK33985.1 - 0.00015 21.2 2.2 0.00018 20.9 0.3 2.1 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 KIK33985.1 - 0.00015 22.0 0.0 0.00061 20.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain Ank_4 PF13637.6 KIK33985.1 - 0.00016 22.2 0.6 2.9 8.6 0.1 5.1 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank PF00023.30 KIK33985.1 - 0.00088 19.6 1.3 3.4 8.3 0.1 5.6 6 0 0 6 6 6 1 Ankyrin repeat AAA_14 PF13173.6 KIK33985.1 - 0.0033 17.4 0.0 5.6 7.0 0.0 3.5 3 1 1 4 4 4 2 AAA domain Zeta_toxin PF06414.12 KIK33985.1 - 0.01 15.1 0.0 0.06 12.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 KIK33985.1 - 0.025 15.0 0.0 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ank_5 PF13857.6 KIK33985.1 - 0.055 13.8 0.2 5.3 7.5 0.0 3.8 4 0 0 4 4 3 0 Ankyrin repeats (many copies) NB-ARC PF00931.22 KIK33985.1 - 0.076 12.2 0.0 0.27 10.4 0.0 1.9 1 1 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 KIK33985.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea CHAT PF12770.7 KIK33987.1 - 5.6e-46 157.3 0.0 1.4e-45 155.9 0.0 1.6 1 0 0 1 1 1 1 CHAT domain Peptidase_C25 PF01364.18 KIK33987.1 - 0.046 12.9 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C25 p450 PF00067.22 KIK33988.1 - 5.8e-64 216.5 0.0 6.7e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF190 PF02641.15 KIK33989.1 - 0.14 12.5 0.0 0.15 12.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized ACR, COG1993 RNA_pol_Rpb2_2 PF04561.14 KIK33991.1 - 0.088 12.4 0.0 0.097 12.3 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 Plavaka PF18759.1 KIK33994.1 - 1.2e-63 215.3 0.0 1.5e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase DUF4438 PF14505.6 KIK33996.1 - 0.047 12.7 0.0 0.055 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4438) RSN1_7TM PF02714.15 KIK33999.1 - 4.7e-82 275.4 27.0 7.4e-82 274.7 27.0 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KIK33999.1 - 8e-37 126.4 4.2 8e-37 126.4 4.2 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KIK33999.1 - 6.1e-27 95.0 0.0 9.9e-26 91.0 0.0 2.2 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KIK33999.1 - 5.7e-11 42.4 0.0 1.1e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter MtrF PF09472.10 KIK33999.1 - 1.6 8.1 6.7 3.8 7.0 0.6 2.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Sec20 PF03908.13 KIK34000.1 - 3.4e-05 23.7 0.1 4.8e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Sec20 RicinB_lectin_2 PF14200.6 KIK34003.1 - 0.029 15.1 4.4 0.56 11.0 0.6 2.6 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like IBR PF01485.21 KIK34005.1 - 3.3e-09 36.8 31.1 1.2e-06 28.6 11.8 2.8 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KIK34005.1 - 0.00066 20.0 4.7 0.00066 20.0 4.7 3.9 3 1 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 KIK34005.1 - 0.0027 17.4 3.9 0.0027 17.4 3.9 3.5 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KIK34005.1 - 0.013 15.3 1.3 0.013 15.3 1.3 4.3 3 2 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FHA PF00498.26 KIK34007.1 - 3.1e-15 56.3 0.1 6.9e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIK34007.1 - 0.14 12.5 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Oxidored_FMN PF00724.20 KIK34009.1 - 5.7e-94 315.2 0.0 6.5e-94 315.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF371 PF04027.13 KIK34010.1 - 0.031 14.3 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF371) DUF4808 PF16066.5 KIK34010.1 - 0.081 13.5 0.2 0.25 11.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4808) HlyD PF00529.20 KIK34010.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 HlyD membrane-fusion protein of T1SS DUF4460 PF14687.6 KIK34014.1 - 0.068 13.2 0.2 0.099 12.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) p450 PF00067.22 KIK34015.1 - 6.1e-47 160.4 0.0 1.2e-46 159.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DDE_3 PF13358.6 KIK34017.1 - 1.9e-10 40.6 0.0 2.2e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3826 PF12875.7 KIK34018.1 - 0.019 15.1 0.1 0.039 14.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) NPAT_C PF15712.5 KIK34018.1 - 0.099 11.3 4.1 0.16 10.6 4.1 1.2 1 0 0 1 1 1 0 NPAT C terminus KDZ PF18758.1 KIK34019.1 - 9e-59 198.8 4.1 1.3e-58 198.2 4.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase zf-primase PF09329.11 KIK34019.1 - 0.34 10.8 3.4 1.3 8.9 0.4 3.2 3 0 0 3 3 3 0 Primase zinc finger zf-U11-48K PF05253.12 KIK34019.1 - 2.6 8.0 4.6 1.4 9.0 0.5 2.6 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger CxC2 PF18803.1 KIK34020.1 - 2.3e-41 140.3 0.3 3.9e-41 139.5 0.3 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK34020.1 - 1.2e-08 35.0 0.4 2.8e-08 33.8 0.4 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK34020.1 - 0.00073 19.4 0.2 0.00073 19.4 0.2 1.9 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases Myb_DNA-bind_3 PF12776.7 KIK34021.1 - 3.6e-10 40.7 0.1 4.3e-10 40.5 0.1 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KIK34021.1 - 3.6e-08 33.7 0.1 5e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 KIK34022.1 - 0.00041 20.0 0.1 0.00055 19.6 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HemolysinCabind PF00353.19 KIK34026.1 - 5.3e-14 51.9 13.1 0.034 14.1 0.0 9.7 8 2 1 10 10 10 4 RTX calcium-binding nonapeptide repeat (4 copies) Cyt-b5 PF00173.28 KIK34026.1 - 0.00019 21.5 8.9 24 5.2 0.1 8.3 6 3 4 10 10 10 3 Cytochrome b5-like Heme/Steroid binding domain DEAD PF00270.29 KIK34027.1 - 2e-38 131.9 0.0 3.4e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 KIK34027.1 - 6.2e-19 68.0 0.3 1.1e-18 67.2 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 KIK34027.1 - 1.1e-17 64.3 0.0 1.8e-16 60.5 0.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK34027.1 - 0.00035 20.6 0.0 0.00086 19.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pro_isomerase PF00160.21 KIK34028.1 - 1.2e-39 136.1 0.1 4.5e-38 131.0 0.1 2.1 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Terminase_2 PF03592.16 KIK34030.1 - 0.049 14.1 1.3 0.05 14.1 0.1 1.6 2 0 0 2 2 2 0 Terminase small subunit p450 PF00067.22 KIK34032.1 - 2e-62 211.5 0.0 5.2e-62 210.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Pkinase_fungal PF17667.1 KIK34033.1 - 1.9e-23 82.9 0.0 2.3e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK34033.1 - 2.1e-06 27.3 0.0 2.8e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK34033.1 - 0.011 15.7 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK34034.1 - 6.6e-10 38.3 0.0 1e-05 24.5 0.0 2.1 1 1 0 2 2 2 2 Fungal protein kinase APH PF01636.23 KIK34034.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK34035.1 - 8.4e-22 77.5 0.0 1.1e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK34035.1 - 7e-06 25.6 0.0 9.2e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK34035.1 - 0.017 15.1 0.1 0.026 14.4 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3593 PF12159.8 KIK34041.1 - 2.5 8.2 8.9 0.49 10.5 0.5 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3593) SPC25 PF06703.11 KIK34041.1 - 7.1 6.4 9.7 0.28 11.0 0.8 2.3 1 1 1 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Abhydrolase_6 PF12697.7 KIK34042.1 - 2e-12 48.2 0.4 2.7e-12 47.8 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK34042.1 - 0.037 13.3 0.0 5.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Gp_dh_C PF02800.20 KIK34047.1 - 0.00051 19.7 0.1 0.00074 19.1 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Hid1 PF12722.7 KIK34048.1 - 2.8 6.0 8.1 3.9 5.5 8.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cys_Met_Meta_PP PF01053.20 KIK34051.1 - 7.3e-123 409.9 0.0 1.5e-121 405.5 0.0 2.0 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KIK34051.1 - 0.00031 20.0 0.0 0.00059 19.1 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 KIK34051.1 - 0.002 16.8 0.0 0.0027 16.3 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 KIK34051.1 - 0.13 11.6 0.1 0.38 10.0 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family zf-MYND PF01753.18 KIK34052.1 - 3.9e-08 33.2 10.2 7.9e-08 32.3 10.2 1.5 1 0 0 1 1 1 1 MYND finger Effector_1 PF04518.12 KIK34052.1 - 0.045 12.9 0.0 0.067 12.3 0.0 1.1 1 0 0 1 1 1 0 Effector from type III secretion system NumbF PF06311.12 KIK34052.1 - 0.089 13.3 0.1 0.92 10.1 0.1 2.2 2 0 0 2 2 2 0 NUMB domain Apq12 PF12716.7 KIK34052.1 - 1.3 9.0 5.9 0.2 11.6 0.7 2.2 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis Cys_Met_Meta_PP PF01053.20 KIK34054.1 - 1.6e-10 40.1 0.0 2.1e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme WD40 PF00400.32 KIK34056.1 - 2e-24 85.3 14.9 6.7e-09 36.2 0.4 5.4 4 1 1 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34056.1 - 1.4e-12 47.7 0.9 0.0058 16.9 0.1 4.1 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK34056.1 - 4.7e-05 22.2 0.7 0.2 10.2 0.0 3.0 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK34056.1 - 0.0005 19.1 0.0 0.28 10.1 0.0 2.9 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4082 PF13313.6 KIK34056.1 - 0.023 14.7 0.3 0.71 9.9 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4082) GST_C PF00043.25 KIK34058.1 - 0.00042 20.5 0.0 0.00073 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK34058.1 - 0.00067 19.8 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK34058.1 - 0.0094 16.0 0.0 0.014 15.4 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-H2C2_2 PF13465.6 KIK34063.1 - 1.2e-09 38.1 6.0 1.9e-07 31.2 0.9 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KIK34063.1 - 0.00015 22.0 23.6 0.00057 20.2 2.9 3.6 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK34063.1 - 0.00018 22.1 11.8 0.0021 18.7 2.4 4.0 4 0 0 4 4 3 2 C2H2-type zinc finger zf-met PF12874.7 KIK34063.1 - 0.00049 20.4 0.3 0.0012 19.2 0.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Zn_clus PF00172.18 KIK34063.1 - 0.0061 16.7 13.1 0.016 15.3 13.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_ribbon_SprT PF17283.2 KIK34063.1 - 0.089 12.7 5.6 0.24 11.3 5.6 1.7 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-Di19 PF05605.12 KIK34063.1 - 0.11 12.8 6.6 1.8 9.0 0.7 2.5 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KIK34063.1 - 0.2 11.7 7.6 1.6 8.8 0.5 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK34063.1 - 0.25 11.7 1.6 3.1 8.2 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 KIK34063.1 - 0.39 10.6 1.6 0.74 9.7 0.1 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 KIK34063.1 - 0.53 10.1 5.9 3 7.7 1.1 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF3466 PF11949.8 KIK34063.1 - 0.53 8.8 2.6 17 3.8 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3466) zf-C2H2_2 PF12756.7 KIK34063.1 - 0.95 9.8 9.8 0.66 10.3 0.5 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Uricase PF01014.18 KIK34064.1 - 3.1e-70 234.5 0.3 3.5e-36 124.3 0.2 2.0 2 0 0 2 2 2 2 Uricase UvrD_C_2 PF13538.6 KIK34068.1 - 0.00023 20.9 0.3 0.0018 18.1 0.3 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KIK34068.1 - 0.082 12.6 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase polyprenyl_synt PF00348.17 KIK34073.1 - 3.3e-84 282.0 0.0 4.1e-84 281.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Proteasome PF00227.26 KIK34077.1 - 1.2e-27 96.7 0.1 1.4e-27 96.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF3638 PF12340.8 KIK34080.1 - 1.2e-87 293.0 0.1 2.1e-87 292.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KIK34080.1 - 1.9e-16 59.1 0.2 4.7e-16 57.9 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) PBP1_TM PF14812.6 KIK34081.1 - 1.2 9.5 6.3 0.56 10.6 3.5 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4554 PF15091.6 KIK34082.1 - 1.4 7.7 3.4 2.7 6.8 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) 40S_SA_C PF16122.5 KIK34082.1 - 5.6 8.4 10.4 0.83 11.1 0.2 4.0 4 0 0 4 4 4 0 40S ribosomal protein SA C-terminus VHS PF00790.19 KIK34084.1 - 1.3e-09 38.0 0.1 1.4e-09 38.0 0.1 1.0 1 0 0 1 1 1 1 VHS domain MS_channel PF00924.18 KIK34085.1 - 0.084 12.4 0.3 0.1 12.2 0.3 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel CheR PF01739.18 KIK34086.1 - 0.086 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Ndc1_Nup PF09531.10 KIK34087.1 - 6.5e-93 312.5 7.1 7.5e-93 312.3 7.1 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup TRAM_LAG1_CLN8 PF03798.16 KIK34088.1 - 3.7e-05 23.5 20.3 6.9e-05 22.7 20.3 1.5 1 1 0 1 1 1 1 TLC domain Ferric_reduct PF01794.19 KIK34089.1 - 6.2e-21 74.8 7.3 6.2e-21 74.8 7.3 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KIK34089.1 - 4.9e-20 72.2 0.0 7.5e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KIK34089.1 - 3.2e-15 56.1 0.0 4.9e-10 39.5 0.1 2.5 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 KIK34089.1 - 0.021 15.5 0.0 1.3 9.7 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF2375 PF09558.10 KIK34092.1 - 0.16 12.0 0.0 9.4 6.3 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2375) CAAD PF14159.6 KIK34093.1 - 0.043 13.6 1.6 58 3.6 0.0 3.8 1 1 3 4 4 4 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF2576 PF10845.8 KIK34093.1 - 0.36 10.5 16.3 7.4 6.3 0.2 4.8 4 1 1 5 5 5 0 Protein of unknown function (DUF2576) Nbs1_C PF08599.10 KIK34093.1 - 1.9 8.7 13.9 6.2 7.0 1.8 4.5 1 1 3 4 4 4 0 DNA damage repair protein Nbs1 Nbs1_C PF08599.10 KIK34098.1 - 1.4 9.1 8.1 87 3.4 2.2 4.1 3 1 1 4 4 4 0 DNA damage repair protein Nbs1 WD40 PF00400.32 KIK34100.1 - 4.7e-11 43.1 0.2 1.7e-10 41.3 0.2 1.9 1 0 0 1 1 1 1 WD domain, G-beta repeat PD40 PF07676.12 KIK34100.1 - 0.0026 17.7 0.1 0.89 9.6 0.0 2.5 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK34100.1 - 0.063 12.2 0.0 0.077 11.9 0.0 1.1 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MMR_HSR1 PF01926.23 KIK34105.1 - 0.031 14.4 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase WD40 PF00400.32 KIK34106.1 - 1.7e-09 38.1 0.8 6.7e-09 36.2 0.8 2.1 1 0 0 1 1 1 1 WD domain, G-beta repeat AAA_16 PF13191.6 KIK34106.1 - 1.8e-05 25.2 0.7 0.0001 22.7 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain Parvo_NS1 PF01057.17 KIK34106.1 - 0.00029 20.0 0.2 0.00065 18.9 0.0 1.6 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 NACHT PF05729.12 KIK34106.1 - 0.00036 20.5 0.1 0.0017 18.3 0.0 2.2 2 1 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 KIK34106.1 - 0.00074 18.8 0.2 0.0021 17.3 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain ATPase_2 PF01637.18 KIK34106.1 - 0.0013 18.7 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK34106.1 - 0.0018 18.5 0.0 0.009 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KIK34106.1 - 0.01 16.2 0.0 0.043 14.3 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KIK34106.1 - 0.016 14.4 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain APS_kinase PF01583.20 KIK34106.1 - 0.052 13.4 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.22 KIK34106.1 - 0.063 13.7 0.1 0.21 12.0 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Sigma54_activ_2 PF14532.6 KIK34106.1 - 0.1 12.7 0.1 2.6 8.1 0.0 3.0 3 1 0 3 3 3 0 Sigma-54 interaction domain AAA_PrkA PF08298.11 KIK34106.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain AAA_19 PF13245.6 KIK34106.1 - 0.12 12.7 0.0 0.82 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain PHD PF00628.29 KIK34108.1 - 1.1 9.2 7.7 0.15 11.9 2.4 2.2 2 0 0 2 2 2 0 PHD-finger Chromo PF00385.24 KIK34109.1 - 1.4e-09 37.8 0.0 1.7e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Glyco_hydro_47 PF01532.20 KIK34111.1 - 1.7e-133 445.9 5.5 1.9e-133 445.7 5.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 RicinB_lectin_2 PF14200.6 KIK34114.1 - 0.0057 17.4 2.6 0.02 15.6 0.8 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Cep57_MT_bd PF06657.13 KIK34116.1 - 0.077 13.5 0.1 0.077 13.5 0.1 2.7 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 WHH PF14414.6 KIK34117.1 - 0.4 10.6 5.1 1.7 8.6 5.2 2.0 1 1 1 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH zf-C2H2 PF00096.26 KIK34119.1 - 3.9e-09 36.5 9.6 5.6e-07 29.7 1.9 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK34119.1 - 3e-07 30.6 11.8 4.7e-05 23.6 4.0 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK34119.1 - 0.00011 22.8 8.5 0.00036 21.1 1.3 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 KIK34119.1 - 0.00044 20.6 1.7 0.0052 17.1 0.1 2.4 2 1 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIK34119.1 - 0.005 17.1 0.1 0.015 15.6 0.0 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KIK34119.1 - 0.0062 17.1 3.6 0.6 10.8 0.7 2.1 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 KIK34119.1 - 0.0089 15.8 0.9 0.017 14.8 0.9 1.5 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-Di19 PF05605.12 KIK34119.1 - 0.033 14.5 4.2 0.065 13.5 4.2 1.5 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 KIK34119.1 - 0.033 14.0 2.6 0.039 13.8 0.3 2.1 1 1 1 2 2 2 0 Rad50 zinc hook motif zf-C2H2_9 PF16293.5 KIK34119.1 - 0.034 14.0 0.4 0.058 13.2 0.1 1.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_6 PF13912.6 KIK34119.1 - 0.71 9.9 6.0 1.1 9.3 1.9 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger Ribosomal_L1 PF00687.21 KIK34122.1 - 2e-46 158.3 2.6 2.3e-46 158.1 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Yae1_N PF09811.9 KIK34123.1 - 0.0017 18.0 1.1 0.0034 17.1 1.1 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal 2OG-FeII_Oxy_3 PF13640.6 KIK34124.1 - 2.6e-11 44.2 0.5 3.2e-11 44.0 0.5 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KIK34124.1 - 0.072 13.8 0.3 0.13 13.0 0.3 1.5 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Moulting_cycle PF04870.16 KIK34126.1 - 0.25 10.6 5.2 0.29 10.4 5.2 1.0 1 0 0 1 1 1 0 Moulting cycle Connexin PF00029.19 KIK34126.1 - 1.2 8.8 2.7 1.3 8.7 2.7 1.0 1 0 0 1 1 1 0 Connexin HSF_DNA-bind PF00447.17 KIK34127.1 - 3.4e-15 56.4 0.2 3.5e-15 56.4 0.2 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding SAM_3 PF18016.1 KIK34127.1 - 0.0056 16.5 0.1 0.0092 15.8 0.1 1.4 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) Plavaka PF18759.1 KIK34128.1 - 2.2e-15 56.7 1.3 6.2e-15 55.2 1.7 1.5 2 0 0 2 2 2 1 Plavaka transposase ScdA_N PF04405.14 KIK34128.1 - 0.11 12.2 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) Plavaka PF18759.1 KIK34129.1 - 4.6e-64 216.7 0.0 5.1e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase DAGK_cat PF00781.24 KIK34129.1 - 0.044 13.4 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Plavaka PF18759.1 KIK34130.1 - 4.9e-18 65.4 0.1 6.3e-18 65.1 0.1 1.1 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2 PF00096.26 KIK34130.1 - 0.0042 17.5 0.1 0.0091 16.4 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK34130.1 - 0.086 13.7 0.1 0.23 12.4 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Pkinase_fungal PF17667.1 KIK34131.1 - 2.2e-18 66.3 0.0 1.1e-15 57.4 0.0 3.0 2 1 0 2 2 2 1 Fungal protein kinase p450 PF00067.22 KIK34133.1 - 7.9e-69 232.6 0.0 9.9e-69 232.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SNF2_N PF00176.23 KIK34134.1 - 5.8e-68 229.2 0.1 1.2e-67 228.1 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KIK34134.1 - 3.8e-40 136.4 0.7 6.9e-39 132.4 0.1 2.9 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 KIK34134.1 - 9.2e-33 113.3 2.9 9.2e-33 113.3 2.9 2.8 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 KIK34134.1 - 9.2e-19 67.8 0.0 6.9e-18 65.0 0.0 2.4 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK34134.1 - 1.6e-08 34.7 0.0 5.6e-08 33.0 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KIK34134.1 - 2.1e-07 30.4 0.0 5.3e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KIK34134.1 - 2.4e-05 24.2 0.2 6.2e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_14 PF13173.6 KIK34134.1 - 0.0084 16.1 0.0 0.037 14.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain DEAD_2 PF06733.15 KIK34134.1 - 0.082 12.5 0.8 0.18 11.4 0.1 1.8 2 0 0 2 2 2 0 DEAD_2 GRP PF07172.11 KIK34135.1 - 0.056 14.1 14.9 0.055 14.1 14.9 1.1 1 0 0 1 1 1 0 Glycine rich protein family Coagulase PF08764.10 KIK34136.1 - 0.012 15.8 0.0 0.012 15.8 0.0 1.1 1 0 0 1 1 1 0 Staphylococcus aureus coagulase Nepo_coat PF03391.15 KIK34138.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Nepovirus coat protein, central domain Plavaka PF18759.1 KIK34139.1 - 7.6e-81 271.8 0.0 6.7e-71 239.2 0.0 2.1 1 1 1 2 2 2 2 Plavaka transposase Uricase PF01014.18 KIK34140.1 - 9.3e-28 97.1 0.0 1.8e-20 73.5 0.0 2.0 2 0 0 2 2 2 2 Uricase CHAT PF12770.7 KIK34141.1 - 5.1e-16 58.9 0.0 5.3e-16 58.9 0.0 1.0 1 0 0 1 1 1 1 CHAT domain Egg_lysin PF01303.17 KIK34142.1 - 0.051 13.8 0.0 0.083 13.1 0.0 1.3 1 0 0 1 1 1 0 Egg lysin (Sperm-lysin) GnHR_trans PF12369.8 KIK34143.1 - 0.0082 16.9 0.8 5.8 7.8 0.0 2.9 1 1 2 3 3 3 3 Gonadotropin hormone receptor transmembrane region GST_C_2 PF13410.6 KIK34143.1 - 0.44 10.6 2.3 71 3.5 0.1 3.3 2 1 2 4 4 4 0 Glutathione S-transferase, C-terminal domain APC_r PF05923.12 KIK34143.1 - 4.7 7.0 10.1 34 4.3 0.2 3.2 3 0 0 3 3 3 0 APC repeat KDZ PF18758.1 KIK34144.1 - 5.1e-43 147.3 0.0 1.5e-40 139.2 0.0 2.4 2 0 0 2 2 2 2 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK34144.1 - 1.3e-37 128.2 0.0 7.7e-37 125.7 0.0 2.4 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK34144.1 - 0.0011 19.1 0.1 0.004 17.3 0.1 1.9 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases BEN PF10523.9 KIK34146.1 - 0.14 12.4 0.2 0.39 11.0 0.2 1.7 1 0 0 1 1 1 0 BEN domain DUF966 PF06136.13 KIK34148.1 - 0.19 11.4 7.3 0.23 11.2 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) HSP70 PF00012.20 KIK34151.1 - 1.8e-35 122.3 0.0 2.1e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein EF1G PF00647.19 KIK34152.1 - 8e-09 35.5 0.0 9.4e-09 35.3 0.0 1.0 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain WD40 PF00400.32 KIK34154.1 - 1.8e-32 110.9 14.5 2e-08 34.8 0.2 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34154.1 - 1.5e-16 60.5 0.0 7.9e-06 26.1 0.0 3.9 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK34154.1 - 1.2e-06 27.7 0.0 0.017 14.1 0.0 3.9 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK34154.1 - 0.01 14.6 0.0 3.7 6.1 0.0 2.9 3 0 0 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.12 KIK34154.1 - 0.13 12.2 4.9 19 5.4 0.1 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RNR_inhib PF08591.10 KIK34156.1 - 0.066 14.5 0.3 0.091 14.1 0.3 1.4 1 1 0 1 1 1 0 Ribonucleotide reductase inhibitor DUF4192 PF13830.6 KIK34161.1 - 0.034 14.2 1.0 0.043 13.9 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) F-box-like PF12937.7 KIK34162.1 - 2.4e-05 24.1 0.1 5.9e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIK34162.1 - 0.031 14.1 0.0 0.08 12.8 0.0 1.7 1 0 0 1 1 1 0 F-box Cation_ATPase_C PF00689.21 KIK34167.1 - 3.2e-21 75.9 13.2 5.2e-21 75.2 13.2 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus SnAC PF14619.6 KIK34167.1 - 5.4e-12 46.2 0.3 1.2e-11 45.0 0.2 1.7 1 1 0 1 1 1 1 Snf2-ATP coupling, chromatin remodelling complex Cation_ATPase_C PF00689.21 KIK34169.1 - 2e-21 76.6 12.7 2.8e-21 76.1 12.7 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KIK34170.1 - 0.00055 19.5 0.2 0.00084 18.9 0.2 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Plavaka PF18759.1 KIK34171.1 - 3.7e-126 420.7 0.0 5.4e-126 420.2 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase DDE_Tnp_4 PF13359.6 KIK34174.1 - 7e-08 32.3 0.2 2e-05 24.3 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease Plavaka PF18759.1 KIK34176.1 - 4.1e-11 42.7 0.0 1e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Plavaka transposase zf-C2HC_2 PF13913.6 KIK34176.1 - 0.46 10.4 2.6 1.1 9.3 2.6 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type KOW PF00467.29 KIK34179.1 - 9e-05 22.3 7.9 0.00091 19.1 0.6 3.4 3 0 0 3 3 3 3 KOW motif FlaC_arch PF05377.11 KIK34180.1 - 0.1 13.0 1.2 0.52 10.7 0.5 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) BEX PF04538.12 KIK34180.1 - 0.11 13.2 0.3 0.17 12.5 0.3 1.4 1 0 0 1 1 1 0 Brain expressed X-linked like family Peptidase_S7 PF00949.21 KIK34180.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease PCMT PF01135.19 KIK34183.1 - 2e-72 243.4 0.1 2.4e-72 243.1 0.1 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KIK34183.1 - 1.5e-09 37.9 0.0 2.6e-09 37.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK34183.1 - 3.6e-06 27.6 0.1 3.1e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK34183.1 - 7.1e-06 26.0 0.0 9.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK34183.1 - 2.4e-05 24.9 0.0 0.00016 22.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 KIK34183.1 - 0.00011 22.3 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK34183.1 - 0.0006 19.4 0.0 0.00097 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KIK34183.1 - 0.0014 18.1 0.0 0.004 16.6 0.0 1.7 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KIK34183.1 - 0.03 14.2 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KIK34183.1 - 0.04 13.5 0.1 0.064 12.8 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.12 KIK34183.1 - 0.041 14.6 0.0 0.08 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain EF-hand_1 PF00036.32 KIK34183.1 - 0.098 12.3 0.1 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 EF hand FtsJ PF01728.19 KIK34183.1 - 0.17 12.0 0.0 0.24 11.5 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Mem_trans PF03547.18 KIK34184.1 - 3.6e-39 134.3 0.9 5.6e-30 104.0 0.0 2.5 2 1 0 2 2 2 2 Membrane transport protein baeRF_family8 PF18851.1 KIK34184.1 - 0.077 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 8 MFS_5 PF05631.14 KIK34185.1 - 1.9e-71 240.9 3.7 2.8e-71 240.3 3.7 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KIK34185.1 - 1.4e-15 57.1 32.7 1.4e-15 57.1 32.7 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily RRM_1 PF00076.22 KIK34186.1 - 1.8e-48 162.2 0.0 2.9e-15 55.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3343 PF11823.8 KIK34186.1 - 0.0037 16.7 0.0 0.022 14.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3343) Limkain-b1 PF11608.8 KIK34186.1 - 0.0062 16.6 0.0 0.23 11.5 0.0 3.1 3 1 0 3 3 3 1 Limkain b1 gpW PF02831.15 KIK34186.1 - 0.072 13.0 0.2 0.63 10.0 0.0 2.4 2 0 0 2 2 2 0 gpW PNISR PF15996.5 KIK34186.1 - 0.91 9.8 10.3 1.5 9.1 10.3 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Apt1 PF10351.9 KIK34186.1 - 5.8 5.6 12.3 7.8 5.2 12.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 KIK34186.1 - 7.5 5.2 5.8 10 4.8 5.8 1.1 1 0 0 1 1 1 0 Presenilin Tet_JBP PF12851.7 KIK34189.1 - 0.0015 17.9 0.0 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily KDZ PF18758.1 KIK34193.1 - 1.8e-62 210.9 0.3 2.1e-62 210.6 0.3 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KIK34196.1 - 7.8e-73 244.8 3.8 2.3e-72 243.2 3.8 1.8 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK34196.1 - 0.0021 18.2 0.1 0.018 15.2 0.0 2.7 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KIK34196.1 - 0.038 14.2 0.0 0.16 12.2 0.0 2.1 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases AalphaY_MDB PF04611.12 KIK34197.1 - 0.17 11.9 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region Filament PF00038.21 KIK34198.1 - 0.024 14.2 4.0 0.039 13.5 0.2 2.2 2 0 0 2 2 2 0 Intermediate filament protein Cauli_VI PF01693.16 KIK34200.1 - 0.0051 17.1 0.0 0.0074 16.6 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Peptidase_C48 PF02902.19 KIK34203.1 - 2e-15 57.2 0.5 3.8e-15 56.3 0.5 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain KDZ PF18758.1 KIK34203.1 - 4.6e-14 52.6 0.0 1e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase MMR_HSR1 PF01926.23 KIK34205.1 - 3.1e-11 43.4 0.0 5.2e-11 42.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK34205.1 - 4.1e-06 26.8 0.1 9.5e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 KIK34205.1 - 3.4e-05 24.0 0.0 8.8e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KIK34205.1 - 0.00011 21.8 0.0 0.00031 20.4 0.0 1.7 1 1 0 1 1 1 1 Ras family ABC_tran PF00005.27 KIK34205.1 - 0.0002 21.9 0.0 0.00032 21.2 0.0 1.5 1 1 0 1 1 1 1 ABC transporter IIGP PF05049.13 KIK34205.1 - 0.00022 20.4 0.2 0.00066 18.8 0.0 1.8 2 1 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 KIK34205.1 - 0.0027 17.0 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 AIG1 family AAA_23 PF13476.6 KIK34205.1 - 0.0051 17.3 1.3 0.012 16.1 0.1 2.0 1 1 2 3 3 3 1 AAA domain AAA_16 PF13191.6 KIK34205.1 - 0.0056 17.1 0.0 0.0094 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 KIK34205.1 - 0.0078 15.5 0.0 0.016 14.5 0.0 1.4 2 0 0 2 2 2 1 Septin AAA_29 PF13555.6 KIK34205.1 - 0.0079 15.9 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 KIK34205.1 - 0.0085 16.2 0.0 0.029 14.4 0.0 1.9 2 0 0 2 2 2 1 Dynamin family AAA_24 PF13479.6 KIK34205.1 - 0.013 15.2 0.0 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 KIK34205.1 - 0.017 14.6 0.3 0.071 12.6 0.0 2.0 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KIK34205.1 - 0.02 14.4 0.0 0.03 13.8 0.0 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B cobW PF02492.19 KIK34205.1 - 0.021 14.4 0.0 0.057 13.0 0.0 1.8 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KIK34205.1 - 0.074 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Virul_Fac PF10139.9 KIK34205.1 - 0.089 11.0 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor RNA_helicase PF00910.22 KIK34205.1 - 0.11 12.8 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.13 KIK34205.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) OCD_Mu_crystall PF02423.15 KIK34206.1 - 1.5e-30 106.2 0.7 8.6e-30 103.8 0.7 2.0 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KIK34206.1 - 0.0026 17.8 0.0 0.0076 16.3 0.0 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TPR_2 PF07719.17 KIK34207.1 - 5.7e-15 54.1 12.3 8.4e-05 22.4 0.0 7.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIK34207.1 - 2e-12 46.4 8.5 0.00021 21.0 0.0 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIK34207.1 - 4.9e-09 36.3 27.3 0.00022 21.8 0.1 8.7 7 2 3 10 10 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK34207.1 - 2e-06 28.2 8.1 0.68 10.5 0.8 5.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK34207.1 - 3.2e-06 26.9 10.4 0.011 15.9 0.0 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK34207.1 - 1.4e-05 25.6 16.7 0.00027 21.5 0.2 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIK34207.1 - 1.6e-05 24.9 2.0 3.1 8.4 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK34207.1 - 0.00023 21.3 5.8 1.1 9.6 0.0 5.5 5 1 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KIK34207.1 - 0.00031 20.6 2.7 0.55 10.4 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIK34207.1 - 0.00064 20.0 15.1 4.8 7.5 0.0 7.8 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 KIK34207.1 - 0.0033 17.5 4.8 2.1 8.5 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KIK34207.1 - 0.027 13.7 2.2 0.15 11.3 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK34207.1 - 0.052 13.2 13.7 2.3 8.0 0.1 5.3 5 1 1 6 6 6 0 TPR repeat TPR_MalT PF17874.1 KIK34207.1 - 1.6 8.0 7.6 31 3.8 0.0 4.8 5 2 0 5 5 5 0 MalT-like TPR region ATP_sub_h PF10775.9 KIK34208.1 - 0.21 11.6 2.4 0.52 10.3 0.2 2.7 3 0 0 3 3 3 0 ATP synthase complex subunit h CinA PF02464.17 KIK34209.1 - 9.4e-31 106.5 0.5 1.1e-30 106.2 0.5 1.0 1 0 0 1 1 1 1 Competence-damaged protein Mif2_N PF15624.6 KIK34212.1 - 0.62 10.8 4.2 0.39 11.4 1.7 1.9 1 1 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal PQQ PF01011.21 KIK34213.1 - 0.069 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat PQQ_2 PF13360.6 KIK34213.1 - 0.081 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 PQQ-like domain zf-PARP PF00645.18 KIK34214.1 - 0.045 14.6 0.2 0.084 13.7 0.2 1.4 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region HOCHOB PF17943.1 KIK34214.1 - 0.072 13.8 0.0 0.1 13.3 0.0 1.3 1 0 0 1 1 1 0 Homeobox-cysteine loop-homeobox Sad1_UNC PF07738.13 KIK34217.1 - 5.9e-28 97.5 0.1 1.1e-27 96.6 0.1 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CI-B14_5a PF07347.12 KIK34217.1 - 0.046 13.6 1.1 0.17 11.7 0.2 2.5 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) ATP-synt_C PF00137.21 KIK34218.1 - 1.4e-34 118.2 35.1 6.3e-22 77.7 15.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C GerA PF03323.13 KIK34218.1 - 2.8 6.3 5.2 6.9 5.0 0.9 2.3 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein 4HBT PF03061.22 KIK34219.1 - 4.5e-13 49.4 0.4 6.7e-13 48.8 0.4 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Kdo PF06293.14 KIK34220.1 - 6e-05 22.5 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L7Ae PF01248.26 KIK34221.1 - 8.8e-14 51.0 0.3 1.7e-13 50.1 0.3 1.5 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Plavaka PF18759.1 KIK34222.1 - 5.2e-37 127.8 0.0 8.9e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase HemolysinCabind PF00353.19 KIK34223.1 - 4e-18 65.1 7.4 0.051 13.6 0.3 9.1 8 1 1 9 9 9 7 RTX calcium-binding nonapeptide repeat (4 copies) Cyt-b5 PF00173.28 KIK34223.1 - 4.1e-05 23.6 0.1 18 5.5 0.0 7.2 8 1 1 9 9 9 1 Cytochrome b5-like Heme/Steroid binding domain HTH_1 PF00126.27 KIK34223.1 - 7.2 6.6 6.1 1.4e+02 2.6 0.0 5.1 7 0 0 7 7 7 0 Bacterial regulatory helix-turn-helix protein, lysR family F-box-like PF12937.7 KIK34224.1 - 9.5e-07 28.6 0.3 2.4e-06 27.3 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK34224.1 - 0.02 14.8 0.8 0.27 11.1 0.5 2.7 2 1 0 2 2 2 0 F-box domain CFAP91 PF14738.6 KIK34228.1 - 0.052 13.6 0.1 0.058 13.4 0.1 1.1 1 0 0 1 1 1 0 Cilia- and flagella-associated protein 91 PATR PF12951.7 KIK34229.1 - 0.041 14.0 0.3 0.47 10.6 0.1 2.3 2 0 0 2 2 2 0 Passenger-associated-transport-repeat DUF3696 PF12476.8 KIK34229.1 - 0.051 14.0 0.2 0.08 13.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) MMR_HSR1 PF01926.23 KIK34230.1 - 0.00091 19.3 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KIK34230.1 - 0.0021 17.5 0.0 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIK34230.1 - 0.0092 15.5 0.1 4 6.9 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Roc PF08477.13 KIK34230.1 - 0.014 15.6 0.0 0.04 14.1 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ADSL_C PF10397.9 KIK34230.1 - 0.032 14.8 0.0 0.062 13.9 0.0 1.5 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus RsgA_GTPase PF03193.16 KIK34230.1 - 0.039 13.9 0.0 7.3 6.5 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 KIK34230.1 - 0.048 12.8 0.2 2 7.5 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit TniB PF05621.11 KIK34230.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein MMR_HSR1 PF01926.23 KIK34233.1 - 1.1e-07 31.9 0.0 2.3e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK34233.1 - 1.4e-05 25.0 0.2 0.0013 18.7 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 KIK34233.1 - 0.0018 17.8 0.0 0.38 10.3 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KIK34233.1 - 0.0021 17.4 0.0 0.0057 16.0 0.0 1.7 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 KIK34233.1 - 0.0034 17.9 0.1 0.0082 16.7 0.1 1.8 1 1 0 1 1 1 1 ABC transporter Septin PF00735.18 KIK34233.1 - 0.0071 15.7 0.0 0.059 12.6 0.0 2.0 2 0 0 2 2 2 1 Septin AAA_16 PF13191.6 KIK34233.1 - 0.0099 16.3 0.0 0.12 12.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 KIK34233.1 - 0.017 15.2 1.9 0.086 12.9 0.6 2.6 2 1 1 3 3 3 0 Dynamin family DUF4203 PF13886.6 KIK34233.1 - 0.022 14.4 1.1 0.033 13.8 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) FeoB_N PF02421.18 KIK34233.1 - 0.024 14.2 0.0 0.17 11.4 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 KIK34233.1 - 0.027 14.7 0.0 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KIK34233.1 - 0.041 13.1 0.0 1.6 7.8 0.0 2.4 2 1 0 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 KIK34233.1 - 0.073 12.6 0.0 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 KIK34233.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain LysR_substrate PF03466.20 KIK34236.1 - 0.0015 18.0 0.1 0.002 17.5 0.1 1.2 1 0 0 1 1 1 1 LysR substrate binding domain GFO_IDH_MocA PF01408.22 KIK34237.1 - 2.3e-15 57.5 0.0 4.1e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIK34237.1 - 0.012 15.7 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KIK34237.1 - 0.2 12.3 0.3 2.7 8.7 0.1 2.3 2 1 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Glyco_hydro_1 PF00232.18 KIK34238.1 - 8.9e-155 515.5 0.6 1.1e-154 515.3 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Zn_clus PF00172.18 KIK34239.1 - 9.3e-06 25.7 8.7 1.7e-05 24.9 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF104 PF01954.16 KIK34239.1 - 0.15 12.5 0.1 0.27 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF104 Apolipoprotein PF01442.18 KIK34242.1 - 2.1 8.2 9.2 0.053 13.4 1.1 2.2 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain CAF20 PF17052.5 KIK34243.1 - 0.71 10.0 8.2 0.49 10.5 5.8 1.7 2 0 0 2 2 2 0 Cap associated factor Cauli_VI PF01693.16 KIK34244.1 - 7.9e-06 26.1 0.1 1e-05 25.7 0.1 1.2 1 0 0 1 1 1 1 Caulimovirus viroplasmin Cauli_VI PF01693.16 KIK34245.1 - 0.00062 20.0 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin KDZ PF18758.1 KIK34246.1 - 1.5e-65 220.9 0.3 2.7e-65 220.1 0.3 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK34246.1 - 1.1e-44 150.9 0.2 1.6e-43 147.3 0.0 2.9 3 0 0 3 3 3 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK34246.1 - 2e-07 31.1 0.0 9.5e-07 28.9 0.0 2.2 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK34246.1 - 0.00045 20.0 0.1 0.00045 20.0 0.1 2.3 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases NOA36 PF06524.12 KIK34247.1 - 0.16 11.2 4.4 0.22 10.8 4.4 1.1 1 0 0 1 1 1 0 NOA36 protein Red1 PF07964.11 KIK34247.1 - 0.19 9.9 1.3 0.24 9.6 1.3 1.1 1 0 0 1 1 1 0 Rec10 / Red1 bMG6 PF17962.1 KIK34248.1 - 0.066 13.4 0.0 0.078 13.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial macroglobulin domain 6 Pro-kuma_activ PF09286.11 KIK34249.1 - 1.8e-25 89.9 0.1 2.5e-25 89.4 0.1 1.2 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Retro_M PF02813.14 KIK34249.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral M domain MutS_II PF05188.17 KIK34250.1 - 4.1e-15 56.3 0.1 7.5e-15 55.4 0.1 1.3 1 0 0 1 1 1 1 MutS domain II AAA PF00004.29 KIK34250.1 - 9.5e-12 45.5 0.1 2.2e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MutS_I PF01624.20 KIK34250.1 - 2.3e-07 31.0 0.0 4.2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 MutS domain I AAA_33 PF13671.6 KIK34250.1 - 0.00011 22.4 0.0 0.00019 21.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KIK34250.1 - 0.00051 19.8 0.1 0.001 18.8 0.1 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KIK34250.1 - 0.0033 16.7 0.0 0.0057 15.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KIK34250.1 - 0.0063 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KIK34250.1 - 0.013 14.9 0.1 0.025 14.0 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KIK34250.1 - 0.023 15.0 0.0 0.065 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIK34250.1 - 0.037 14.4 0.0 0.12 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 KIK34250.1 - 0.043 13.6 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KIK34250.1 - 0.12 12.9 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK34250.1 - 0.13 12.7 0.0 0.38 11.2 0.0 1.8 2 0 0 2 2 2 0 RNA helicase PhoH PF02562.16 KIK34250.1 - 0.23 10.9 0.0 0.38 10.2 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein Plavaka PF18759.1 KIK34251.1 - 4.3e-31 108.3 0.0 8.5e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase F-box-like PF12937.7 KIK34253.1 - 0.026 14.4 0.3 0.084 12.8 0.1 2.0 2 0 0 2 2 2 0 F-box-like FmiP_Thoc5 PF09766.9 KIK34254.1 - 1 8.6 0.0 1 8.6 0.0 2.1 1 1 1 2 2 2 0 Fms-interacting protein/Thoc5 cwf18 PF08315.12 KIK34254.1 - 1.5 9.5 4.6 5.3 7.7 4.6 1.9 1 1 0 1 1 1 0 cwf18 pre-mRNA splicing factor DUF515 PF04415.12 KIK34254.1 - 4.1 5.7 17.9 0.024 13.0 8.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF515) TFIIA PF03153.13 KIK34254.1 - 6.1 6.7 14.6 8.8 6.2 14.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 KIK34255.1 - 3.5e-31 106.7 2.2 3.2e-08 34.1 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34255.1 - 3e-10 40.2 0.4 0.02 15.2 0.0 4.8 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK34255.1 - 4.3e-09 35.6 0.0 0.0042 15.8 0.0 3.1 3 0 0 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.12 KIK34255.1 - 0.0036 17.2 1.1 2.3 8.3 0.0 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK34255.1 - 0.045 13.1 0.0 8.4 5.6 0.0 2.9 4 0 0 4 4 4 0 WD40-like domain Nbas_N PF15492.6 KIK34255.1 - 0.13 11.5 0.1 2.3 7.5 0.0 2.5 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 KIK34255.1 - 0.15 10.8 0.0 11 4.7 0.0 2.5 2 1 0 2 2 2 0 Nup133 N terminal like Ge1_WD40 PF16529.5 KIK34255.1 - 0.16 10.9 0.0 14 4.5 0.0 2.5 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KIK34256.1 - 1.9e-20 72.8 13.5 1.3e-08 35.3 1.9 6.4 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34256.1 - 2e-16 60.0 0.4 0.0014 18.9 0.0 6.2 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK34256.1 - 2.5e-09 36.8 0.0 6.6 6.8 0.0 6.6 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KIK34256.1 - 9.3e-07 28.9 0.1 0.0055 16.6 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 KIK34256.1 - 0.00021 21.0 2.4 0.0062 16.1 1.9 2.5 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 KIK34256.1 - 0.0011 19.4 0.8 1.9 9.1 1.1 3.6 3 0 0 3 3 3 1 PQQ-like domain Nbas_N PF15492.6 KIK34256.1 - 0.0021 17.5 0.2 1.1 8.5 0.0 3.5 2 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal SGL PF08450.12 KIK34256.1 - 0.0021 17.7 0.1 1.8 8.1 0.0 2.7 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region PQQ PF01011.21 KIK34256.1 - 0.0027 17.6 0.2 12 6.0 0.0 4.6 4 0 0 4 4 4 1 PQQ enzyme repeat Ge1_WD40 PF16529.5 KIK34256.1 - 0.0075 15.3 0.0 0.95 8.4 0.0 3.6 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein RAB3GAP2_N PF14655.6 KIK34256.1 - 0.0099 15.2 0.1 0.44 9.7 0.0 2.4 2 1 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40_like PF17005.5 KIK34256.1 - 0.012 14.9 0.0 0.059 12.7 0.0 1.9 1 1 1 2 2 2 0 WD40-like domain Nup160 PF11715.8 KIK34256.1 - 0.06 12.0 3.2 5 5.6 0.4 3.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 WD40 PF00400.32 KIK34258.1 - 2.4e-25 88.3 0.4 1.6e-07 31.9 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34258.1 - 1.3e-06 28.6 0.1 0.19 12.1 0.0 3.6 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 KIK34258.1 - 4e-05 22.9 0.2 0.00098 18.3 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1513) Nbas_N PF15492.6 KIK34258.1 - 0.0014 18.0 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KIK34258.1 - 0.037 14.0 0.0 0.99 9.4 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK34258.1 - 0.039 12.6 0.0 0.057 12.1 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KIK34258.1 - 0.056 13.0 0.1 0.082 12.5 0.1 1.3 1 1 0 1 1 1 0 PQQ-like domain Pkinase_fungal PF17667.1 KIK34259.1 - 8e-08 31.5 0.0 8.8e-08 31.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase DEC-1_N PF04625.13 KIK34260.1 - 0.081 11.9 2.1 0.11 11.5 2.1 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DDE_Tnp_4 PF13359.6 KIK34262.1 - 6.8e-07 29.1 0.0 2.5e-05 24.0 0.0 2.1 1 1 1 2 2 2 2 DDE superfamily endonuclease Phosducin PF02114.16 KIK34263.1 - 9.4e-16 57.5 0.0 9.9e-08 31.2 0.0 3.1 2 1 1 3 3 3 3 Phosducin F-box-like PF12937.7 KIK34265.1 - 0.0034 17.2 0.0 0.015 15.2 0.0 2.2 1 1 0 1 1 1 1 F-box-like p450 PF00067.22 KIK34267.1 - 3.3e-70 237.1 0.0 3.8e-70 236.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Inhibitor_I10 PF12559.8 KIK34267.1 - 0.015 15.5 0.0 0.049 13.9 0.0 1.9 1 0 0 1 1 1 0 Serine endopeptidase inhibitors DltD PF04914.12 KIK34268.1 - 0.13 11.6 0.0 0.13 11.6 0.0 1.0 1 0 0 1 1 1 0 DltD protein DUF5063 PF16702.5 KIK34270.1 - 0.027 14.9 0.1 0.085 13.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5063) IL31 PF15209.6 KIK34270.1 - 0.082 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Interleukin 31 Pyr_redox_3 PF13738.6 KIK34271.1 - 1.4e-19 70.5 0.0 1.7e-18 66.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KIK34271.1 - 1.1e-18 67.0 0.0 9.8e-17 60.6 0.0 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KIK34271.1 - 5.3e-17 62.0 0.6 6.7e-13 48.5 0.1 2.9 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK34271.1 - 8.1e-13 48.2 0.0 7.6e-11 41.7 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KIK34271.1 - 1.1e-07 31.9 0.8 2.3e-07 30.9 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KIK34271.1 - 1.5e-07 31.6 0.4 0.00024 21.1 0.0 3.3 3 1 1 4 4 4 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KIK34271.1 - 6.7e-07 28.9 0.1 1.3e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KIK34271.1 - 1.4e-06 27.3 0.1 7.8e-05 21.5 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.27 KIK34271.1 - 1.7e-06 28.5 1.6 0.0025 18.3 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK34271.1 - 2.4e-06 27.4 1.9 0.00039 20.1 0.2 3.2 3 1 0 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KIK34271.1 - 5.7e-05 23.2 0.6 0.0016 18.6 0.0 2.6 3 0 0 3 3 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KIK34271.1 - 0.00036 19.7 0.2 0.00036 19.7 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 KIK34271.1 - 0.0015 18.9 0.0 0.21 12.1 0.0 2.6 3 0 0 3 3 2 1 Putative NAD(P)-binding GIDA PF01134.22 KIK34271.1 - 0.0016 17.6 2.3 0.15 11.1 0.1 3.2 3 1 1 4 4 4 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KIK34271.1 - 0.013 14.8 0.7 0.023 14.1 0.7 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KIK34271.1 - 0.039 13.3 0.1 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 KIK34271.1 - 0.04 13.2 0.2 1.1 8.5 0.4 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 2-Hacid_dh_C PF02826.19 KIK34271.1 - 0.05 13.0 0.0 6.2 6.1 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 KIK34271.1 - 0.063 12.5 0.6 0.5 9.6 0.0 2.5 3 0 0 3 3 3 0 Thi4 family Trp_halogenase PF04820.14 KIK34271.1 - 0.066 12.0 0.6 0.14 10.9 0.2 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 KIK34271.1 - 0.075 12.1 3.3 0.11 11.5 0.2 2.6 3 1 0 3 3 3 0 Lycopene cyclase protein TrkA_N PF02254.18 KIK34271.1 - 0.19 12.0 0.1 3.1 8.1 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain DUF4147 PF13660.6 KIK34271.1 - 0.21 11.1 0.0 0.83 9.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) JmjC PF02373.22 KIK34272.1 - 0.01 16.3 0.1 0.032 14.7 0.1 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KIK34272.1 - 0.05 13.3 0.1 0.14 11.9 0.1 1.8 1 1 0 1 1 1 0 Cupin-like domain Cation_ATPase_C PF00689.21 KIK34276.1 - 4.9e-32 111.1 3.0 6.1e-19 68.4 0.0 2.3 1 1 1 2 2 2 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KIK34276.1 - 1.8e-15 57.8 1.0 9.9e-15 55.4 1.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KIK34276.1 - 7.9e-05 22.5 1.6 0.00068 19.5 1.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIK34276.1 - 0.089 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIK34276.1 - 0.19 11.8 0.0 4.2 7.5 0.0 2.5 2 1 0 2 2 2 0 Cation transport ATPase (P-type) GNAT_acetyltr_2 PF13718.6 KIK34278.1 - 1.4e-91 306.0 0.0 2.3e-91 305.2 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KIK34278.1 - 9.7e-87 290.6 0.0 1.5e-86 290.0 0.0 1.3 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KIK34278.1 - 3e-65 219.4 0.0 1.4e-64 217.2 0.0 2.1 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KIK34278.1 - 1.3e-32 111.6 0.0 3.4e-32 110.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KIK34278.1 - 0.00092 19.0 0.2 0.09 12.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain Acetyltransf_7 PF13508.7 KIK34278.1 - 0.043 14.2 0.0 0.19 12.2 0.0 2.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DEAD PF00270.29 KIK34278.1 - 0.084 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Sugar_tr PF00083.24 KIK34279.1 - 3.3e-36 125.1 25.3 4.7e-36 124.6 25.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK34279.1 - 2.1e-35 122.3 31.2 2.1e-35 122.3 31.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily NCE101 PF11654.8 KIK34283.1 - 0.02 14.6 0.0 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 Non-classical export protein 1 JmjN PF02375.17 KIK34283.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 jmjN domain Cytochrom_B558a PF05038.13 KIK34283.1 - 0.23 11.0 1.5 0.53 9.8 0.2 2.1 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit NCE101 PF11654.8 KIK34284.1 - 0.022 14.4 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Non-classical export protein 1 7TM-7TMR_HD PF07698.11 KIK34285.1 - 0.0015 18.3 0.9 0.0017 18.2 0.9 1.2 1 0 0 1 1 1 1 7TM receptor with intracellular HD hydrolase FtsK_4TM PF13491.6 KIK34285.1 - 0.022 14.5 0.7 0.03 14.0 0.7 1.1 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE AMP-binding PF00501.28 KIK34287.1 - 1.3e-62 211.8 0.0 1.7e-62 211.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 KIK34287.1 - 1.6e-30 106.9 0.0 9e-30 104.5 0.0 2.2 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 KIK34287.1 - 1.5e-10 41.2 0.0 5.5e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 KIK34287.1 - 0.00044 20.9 0.1 0.0012 19.5 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK34287.1 - 0.021 14.1 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PE-PPE PF08237.11 KIK34287.1 - 0.099 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain ARD PF03079.14 KIK34288.1 - 1.1e-44 152.4 0.1 1.3e-44 152.1 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KIK34288.1 - 1.4e-09 37.6 0.4 2.7e-09 36.6 0.1 1.6 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 KIK34288.1 - 1.1e-07 31.8 0.1 1.8e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KIK34288.1 - 0.00066 19.3 0.0 0.0012 18.5 0.0 1.5 1 1 0 1 1 1 1 Cupin Cupin_8 PF13621.6 KIK34288.1 - 0.0035 17.1 0.0 0.0067 16.2 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_3 PF05899.12 KIK34288.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) SPAR_C PF11881.8 KIK34290.1 - 0.026 14.4 0.7 0.029 14.3 0.7 1.1 1 0 0 1 1 1 0 C-terminal domain of SPAR protein Pribosyltran_N PF13793.6 KIK34290.1 - 0.07 13.1 0.0 0.092 12.7 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase Plavaka PF18759.1 KIK34293.1 - 1.7e-36 126.1 0.0 2.7e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase KDZ PF18758.1 KIK34294.1 - 1.6e-40 139.1 4.2 4.5e-40 137.6 4.2 1.7 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK34294.1 - 6.8e-28 97.0 1.0 1.7e-27 95.7 0.1 2.1 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK34294.1 - 6.7e-06 26.2 0.1 1.5e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK34294.1 - 0.00061 19.6 0.4 0.0016 18.2 0.1 1.9 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases Tet_JBP PF12851.7 KIK34295.1 - 5.6e-06 25.9 0.0 7.9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily FYVE_2 PF02318.16 KIK34296.1 - 0.0015 18.8 0.1 0.0036 17.5 0.1 1.6 2 0 0 2 2 2 1 FYVE-type zinc finger PHD PF00628.29 KIK34296.1 - 0.031 14.2 5.6 0.045 13.6 5.6 1.3 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.16 KIK34296.1 - 0.21 11.9 6.0 1.1 9.7 5.3 2.1 2 0 0 2 2 2 0 C1 domain zf-piccolo PF05715.13 KIK34296.1 - 0.38 10.9 4.2 0.82 9.9 4.2 1.7 1 0 0 1 1 1 0 Piccolo Zn-finger CK_II_beta PF01214.18 KIK34296.1 - 0.69 9.7 2.0 1.1 9.1 2.0 1.2 1 0 0 1 1 1 0 Casein kinase II regulatory subunit FYVE PF01363.21 KIK34296.1 - 0.9 9.7 5.2 1.5 9.0 5.2 1.4 1 0 0 1 1 1 0 FYVE zinc finger Zn_clus PF00172.18 KIK34299.1 - 0.00021 21.3 7.5 0.018 15.2 2.0 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain KcnmB2_inactiv PF09303.10 KIK34301.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 KCNMB2, ball and chain domain Myb_DNA-bind_3 PF12776.7 KIK34302.1 - 5.2e-11 43.4 0.5 6.9e-11 43.0 0.5 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KIK34302.1 - 6.4e-08 32.9 0.1 1.1e-07 32.1 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain HTH_Tnp_4 PF13613.6 KIK34304.1 - 0.047 13.4 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Pkinase_fungal PF17667.1 KIK34306.1 - 0.0055 15.5 0.1 0.0062 15.4 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Destabilase PF05497.12 KIK34306.1 - 0.14 12.5 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 Destabilase Peroxidase_2 PF01328.17 KIK34308.1 - 5e-44 151.1 0.0 6.5e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 DnaJ PF00226.31 KIK34309.1 - 9.6e-20 70.5 0.3 9.6e-20 70.5 0.3 1.9 2 0 0 2 2 2 1 DnaJ domain Stm1_N PF09598.10 KIK34309.1 - 0.11 13.3 0.2 0.11 13.3 0.2 2.8 1 1 1 2 2 2 0 Stm1 DnaJ PF00226.31 KIK34310.1 - 2.6e-15 56.3 1.1 4.1e-15 55.6 1.1 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3772 PF12607.8 KIK34310.1 - 0.0016 18.2 1.5 0.0017 18.1 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3772) CPP1-like PF11833.8 KIK34310.1 - 0.19 11.4 0.0 1.2 8.7 0.1 2.0 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Amino_oxidase PF01593.24 KIK34311.1 - 1.8e-37 129.8 0.0 4.4e-37 128.4 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK34311.1 - 1.5e-08 34.8 0.0 5e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Tnp_P_element PF12017.8 KIK34311.1 - 0.081 12.3 0.0 0.59 9.5 0.0 2.2 2 0 0 2 2 2 0 Transposase protein DUF1391 PF07151.12 KIK34312.1 - 0.029 14.2 0.1 0.046 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) AHJR-like PF18743.1 KIK34312.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 REase_AHJR-like zf-Sec23_Sec24 PF04810.15 KIK34314.1 - 1e-06 28.7 0.9 1.8e-06 27.8 0.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Mit_KHE1 PF10173.9 KIK34316.1 - 0.047 13.8 1.5 0.054 13.6 1.5 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related SBP_bac_5 PF00496.22 KIK34316.1 - 0.19 10.7 0.2 0.24 10.3 0.2 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle IBN_N PF03810.19 KIK34319.1 - 4.3e-08 33.0 0.0 7.5e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain Ldh_1_N PF00056.23 KIK34320.1 - 1.3e-26 93.4 0.0 1.5e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain eIF-5_eIF-2B PF01873.17 KIK34322.1 - 3.8e-25 88.0 0.1 9.1e-25 86.8 0.0 1.6 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 KIK34322.1 - 3.1e-09 36.8 0.1 7.7e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon BTB_3 PF16017.5 KIK34322.1 - 0.044 13.9 0.0 0.095 12.8 0.0 1.5 2 0 0 2 2 2 0 BTB/POZ domain UME PF08064.13 KIK34322.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 UME (NUC010) domain RPN2_C PF18004.1 KIK34323.1 - 1.5e-27 96.5 0.5 1.7e-26 93.0 0.5 2.1 1 1 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KIK34323.1 - 3.1e-07 30.5 10.4 5.9e-07 29.6 0.1 4.8 5 1 0 5 5 5 1 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KIK34323.1 - 1.8e-06 28.3 0.0 4.6e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 HEAT repeats LisH PF08513.11 KIK34326.1 - 0.0011 18.9 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 LisH DUF1688 PF07958.11 KIK34328.1 - 0.088 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) FAD_binding_3 PF01494.19 KIK34329.1 - 8.9e-21 74.5 0.0 5.7e-10 39.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KIK34329.1 - 0.0049 17.1 0.6 0.011 16.0 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAGLU_C PF12972.7 KIK34329.1 - 0.031 13.8 0.0 0.095 12.2 0.0 1.7 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain SE PF08491.10 KIK34329.1 - 0.036 13.1 0.0 0.27 10.3 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_2 PF07992.14 KIK34329.1 - 0.088 12.0 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIK34329.1 - 0.095 11.5 0.2 0.14 10.9 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase DAO PF01266.24 KIK34329.1 - 0.9 9.0 2.8 4.5 6.8 1.9 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase zf-NOSIP PF15906.5 KIK34330.1 - 9.7e-13 48.1 0.3 2e-12 47.1 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_3 PF13920.6 KIK34330.1 - 1.5e-09 37.6 18.5 4.7e-05 23.1 9.7 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK34330.1 - 3.1e-07 30.6 18.0 8.2e-05 22.9 8.9 2.3 2 0 0 2 2 2 2 Ring finger domain zf-RING_UBOX PF13445.6 KIK34330.1 - 3.8e-07 30.0 13.2 0.0038 17.2 1.2 2.9 2 1 0 2 2 2 2 RING-type zinc-finger zf-RING_5 PF14634.6 KIK34330.1 - 1.9e-05 24.5 21.1 4.4e-05 23.3 9.3 2.7 2 1 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIK34330.1 - 4.9e-05 23.1 18.6 0.0083 16.0 8.7 3.0 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KIK34330.1 - 8.6e-05 22.3 21.1 0.0088 15.9 10.6 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK34330.1 - 9.7e-05 22.1 20.9 0.022 14.6 10.3 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Atg14 PF10186.9 KIK34330.1 - 0.00028 20.1 5.9 0.00049 19.3 5.9 1.4 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 zf-TFIIIC PF12660.7 KIK34330.1 - 0.00096 19.1 3.2 0.045 13.7 0.1 2.4 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex zf-C3HC4_5 PF17121.5 KIK34330.1 - 0.011 15.6 9.9 0.011 15.6 9.9 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DivIC PF04977.15 KIK34330.1 - 0.063 13.1 2.7 0.16 11.8 2.7 1.7 1 0 0 1 1 1 0 Septum formation initiator zf-C3HC4_4 PF15227.6 KIK34330.1 - 0.13 12.5 14.0 0.53 10.5 1.3 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KIK34330.1 - 0.23 11.6 18.3 0.24 11.5 10.8 2.5 2 1 0 2 2 2 0 zinc RING finger of MSL2 DUF3337 PF11816.8 KIK34330.1 - 0.23 11.3 1.6 0.31 10.9 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3337) LsmAD PF06741.13 KIK34330.1 - 0.39 11.3 8.0 0.086 13.4 2.8 2.2 2 0 0 2 2 2 0 LsmAD domain FYVE PF01363.21 KIK34330.1 - 0.43 10.7 11.9 0.28 11.4 3.5 2.9 2 1 0 2 2 2 0 FYVE zinc finger zinc-ribbons_6 PF07191.12 KIK34330.1 - 1.5 8.8 13.6 4.8 7.2 5.4 2.5 2 0 0 2 2 2 0 zinc-ribbons G-gamma PF00631.22 KIK34330.1 - 2.6 8.1 5.0 6.9 6.8 5.0 1.7 1 0 0 1 1 1 0 GGL domain IATP PF04568.12 KIK34330.1 - 7.5 7.1 14.0 2.4 8.6 0.1 3.2 4 0 0 4 4 2 0 Mitochondrial ATPase inhibitor, IATP DZR PF12773.7 KIK34330.1 - 8.4 6.5 13.6 5.4 7.1 4.3 2.8 2 1 0 2 2 2 0 Double zinc ribbon ThiF PF00899.21 KIK34332.1 - 9.2e-38 130.0 0.0 1.3e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KIK34332.1 - 0.00013 22.2 3.5 0.00065 20.0 1.3 2.5 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KIK34332.1 - 0.00023 21.6 0.1 0.00055 20.3 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 KIK34332.1 - 0.028 14.3 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KIK34332.1 - 0.073 13.3 0.2 0.21 11.9 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain DAO PF01266.24 KIK34332.1 - 0.1 12.2 0.2 0.17 11.5 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 KIK34332.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 KIK34332.1 - 0.13 11.8 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CHAT PF12770.7 KIK34333.1 - 1.1e-36 126.7 0.0 1.4e-36 126.4 0.0 1.0 1 0 0 1 1 1 1 CHAT domain Surp PF01805.20 KIK34333.1 - 0.0015 18.5 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Surp module FSIP2 PF15783.5 KIK34333.1 - 0.082 10.8 0.0 0.11 10.4 0.0 1.1 1 0 0 1 1 1 0 Fibrous sheath-interacting protein 2 Cauli_VI PF01693.16 KIK34337.1 - 0.00086 19.6 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin KDZ PF18758.1 KIK34338.1 - 1.8e-67 227.2 0.0 2.6e-67 226.7 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK34338.1 - 2e-43 146.9 0.1 6.2e-43 145.3 0.0 1.9 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK34338.1 - 8.9e-06 25.8 0.0 2.5e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases YL1_C PF08265.11 KIK34339.1 - 5.8e-16 58.0 0.3 8.7e-16 57.4 0.3 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Activator_LAG-3 PF11498.8 KIK34339.1 - 0.07 12.1 0.1 0.09 11.7 0.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 zf-HIT PF04438.16 KIK34339.1 - 0.15 11.9 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 HIT zinc finger SSF PF00474.17 KIK34340.1 - 2.5e-16 59.5 38.2 2.5e-16 59.5 38.2 2.2 2 1 0 2 2 2 1 Sodium:solute symporter family CYYR1 PF10873.8 KIK34340.1 - 1.2 9.6 7.3 8.4 6.8 4.7 2.8 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 F-box-like PF12937.7 KIK34341.1 - 0.12 12.3 1.8 0.57 10.1 0.0 3.0 3 0 0 3 3 3 0 F-box-like Pkinase_Tyr PF07714.17 KIK34342.1 - 4e-19 68.9 0.0 5.6e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK34342.1 - 2.1e-18 66.7 0.0 3e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Alpha_kinase PF02816.18 KIK34342.1 - 0.0029 17.7 0.1 0.0046 17.1 0.1 1.2 1 0 0 1 1 1 1 Alpha-kinase family Seadorna_VP7 PF07387.11 KIK34342.1 - 0.0039 16.3 0.1 0.0062 15.6 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 KIK34342.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KIK34342.1 - 0.015 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family gag-asp_proteas PF13975.6 KIK34347.1 - 0.00024 21.6 0.0 0.0003 21.3 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIK34347.1 - 0.0034 18.0 0.0 0.0043 17.7 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease zf-RVT PF13966.6 KIK34349.1 - 1.7e-05 25.4 0.1 2.4e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase SseC PF04888.12 KIK34353.1 - 0.00076 19.2 6.0 0.0013 18.4 6.0 1.4 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family RmuC PF02646.16 KIK34353.1 - 0.0017 17.5 0.3 0.83 8.7 0.2 2.2 2 0 0 2 2 2 2 RmuC family FUSC PF04632.12 KIK34353.1 - 0.0033 16.0 2.3 0.0046 15.6 2.3 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family Laminin_II PF06009.12 KIK34353.1 - 0.0045 17.0 1.2 0.0094 16.0 1.2 1.5 1 0 0 1 1 1 1 Laminin Domain II Herpes_BLRF2 PF05812.12 KIK34353.1 - 0.11 12.6 0.8 3.4 7.8 0.2 2.5 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein Baculo_PEP_C PF04513.12 KIK34353.1 - 0.23 11.5 3.0 0.71 9.9 0.7 2.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 KIK34353.1 - 0.44 10.7 2.8 0.35 11.1 1.0 1.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 KIK34353.1 - 1.3 9.6 4.3 14 6.3 0.3 2.9 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein tRNA_lig_CPD PF08302.11 KIK34354.1 - 0.041 13.3 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain Plavaka PF18759.1 KIK34355.1 - 5.5e-45 154.0 0.1 7.8e-45 153.5 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase DivIC PF04977.15 KIK34356.1 - 0.00048 19.9 1.9 0.0011 18.7 1.9 1.6 1 0 0 1 1 1 1 Septum formation initiator DUF5383 PF17355.2 KIK34356.1 - 0.012 15.9 2.2 0.074 13.4 1.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5383) YabA PF06156.13 KIK34356.1 - 0.013 16.1 0.8 0.027 15.1 0.8 1.4 1 0 0 1 1 1 0 Initiation control protein YabA NRBF2 PF08961.10 KIK34356.1 - 0.063 12.9 1.8 0.11 12.1 1.8 1.3 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator ZapB PF06005.12 KIK34356.1 - 0.068 13.6 3.7 0.14 12.6 3.7 1.4 1 0 0 1 1 1 0 Cell division protein ZapB HAP1_N PF04849.13 KIK34356.1 - 0.25 10.5 4.2 0.34 10.1 2.4 1.8 1 1 1 2 2 2 0 HAP1 N-terminal conserved region GIT_CC PF16559.5 KIK34356.1 - 0.43 10.5 2.8 0.82 9.6 2.8 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor KDZ PF18758.1 KIK34357.1 - 1e-58 198.6 0.0 1.4e-58 198.2 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CAS_CSE1 PF03378.15 KIK34359.1 - 9e-15 54.1 0.2 1e-14 53.9 0.2 1.1 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Plavaka PF18759.1 KIK34360.1 - 3.2e-30 105.5 0.0 6.8e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase Pkinase PF00069.25 KIK34363.1 - 0.00031 20.2 0.0 0.00033 20.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Aldo_ket_red PF00248.21 KIK34367.1 - 9e-67 225.3 0.2 1e-66 225.1 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 KIK34368.1 - 2.9e-24 85.7 23.1 3.4e-24 85.4 23.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK34368.1 - 0.00064 18.7 5.2 0.0011 18.0 5.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KIK34368.1 - 0.00091 18.6 0.1 0.00091 18.6 0.1 2.5 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB TPPK_C PF12555.8 KIK34368.1 - 2.3 8.3 7.4 1.5 9.0 0.1 3.1 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal MFS_1 PF07690.16 KIK34369.1 - 1.5e-24 86.6 28.0 5.5e-24 84.7 22.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIK34369.1 - 0.00069 18.2 0.2 0.00069 18.2 0.2 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIK34369.1 - 0.0017 17.3 14.4 0.0023 16.9 0.7 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KIK34370.1 - 3.3e-25 88.8 41.6 3.4e-18 65.7 11.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK34370.1 - 1.3e-06 27.5 2.0 1.3e-06 27.5 2.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter DUF4238 PF14022.6 KIK34372.1 - 3.7e-31 108.6 0.2 5.6e-31 108.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) RGS PF00615.19 KIK34372.1 - 0.024 14.9 0.1 0.066 13.5 0.1 1.7 1 0 0 1 1 1 0 Regulator of G protein signaling domain Aldo_ket_red PF00248.21 KIK34373.1 - 2.2e-71 240.5 0.1 2.4e-71 240.3 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4238 PF14022.6 KIK34374.1 - 2e-22 80.0 0.0 1.4e-21 77.2 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF4238) TRI5 PF06330.11 KIK34375.1 - 1.9e-18 66.5 0.1 2.3e-18 66.2 0.1 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Terpene_synth_C PF03936.16 KIK34375.1 - 0.016 14.6 0.1 0.07 12.5 0.1 1.9 1 1 0 1 1 1 0 Terpene synthase family, metal binding domain Acetyltransf_1 PF00583.25 KIK34376.1 - 2e-12 47.4 0.0 2.5e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK34376.1 - 8.5e-10 38.7 0.0 1.2e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK34376.1 - 7.2e-09 36.0 0.0 9.6e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_L24e PF01246.20 KIK34377.1 - 5.6e-29 100.2 0.4 5.6e-29 100.2 0.4 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e Amidase PF01425.21 KIK34381.1 - 2e-80 271.0 0.0 9.2e-80 268.8 0.0 1.8 1 1 0 1 1 1 1 Amidase Amidase PF01425.21 KIK34383.1 - 1.6e-69 235.0 0.0 1.9e-69 234.8 0.0 1.0 1 0 0 1 1 1 1 Amidase WD40 PF00400.32 KIK34388.1 - 3.7e-33 113.0 19.3 2.9e-06 27.9 0.0 8.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34388.1 - 2.5e-12 46.9 0.1 0.014 15.7 0.0 5.5 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 KIK34388.1 - 5.4e-10 39.8 2.9 1.7e-07 31.7 0.3 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) eIF2A PF08662.11 KIK34388.1 - 8e-07 29.1 0.0 0.028 14.3 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK34388.1 - 0.0029 16.6 0.2 0.17 10.8 0.1 3.0 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_14 PF13428.6 KIK34388.1 - 0.012 16.4 3.9 6.9 7.8 0.1 4.1 2 1 1 3 3 3 0 Tetratricopeptide repeat PD40 PF07676.12 KIK34388.1 - 0.23 11.5 0.9 21 5.2 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat TPR_16 PF13432.6 KIK34388.1 - 2 9.1 3.9 1.3e+02 3.3 0.1 4.0 3 2 1 4 4 4 0 Tetratricopeptide repeat HET PF06985.11 KIK34391.1 - 2.2e-11 44.3 3.2 2.3e-09 37.8 0.2 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_1 PF00515.28 KIK34391.1 - 0.00081 19.1 0.1 0.84 9.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK34391.1 - 0.0012 18.8 0.7 0.34 11.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK34391.1 - 0.0025 17.7 1.0 2.6 8.3 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK34391.1 - 0.007 17.1 0.3 16 6.7 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK34391.1 - 0.039 14.6 0.9 0.96 10.1 0.2 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK34391.1 - 0.11 13.0 0.6 25 5.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 KIK34391.1 - 0.24 11.5 0.5 9.4 6.3 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Mannosidase_ig PF17786.1 KIK34392.1 - 3.4e-07 30.8 0.0 6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain WD40 PF00400.32 KIK34394.1 - 5e-34 115.8 31.1 1.4e-07 32.0 0.6 7.4 8 0 0 8 8 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34394.1 - 4.6e-17 62.1 4.3 0.00032 20.9 0.0 5.9 2 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK34394.1 - 1.9e-09 36.7 2.2 0.0034 16.1 2.0 4.0 2 2 1 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK34394.1 - 2.3e-08 33.4 0.7 0.49 9.3 0.0 4.8 2 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KIK34394.1 - 0.00044 18.9 0.6 0.091 11.3 0.1 2.4 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nbas_N PF15492.6 KIK34394.1 - 0.00049 19.5 1.1 0.49 9.7 0.1 3.0 2 2 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 KIK34394.1 - 0.0009 18.1 0.8 0.026 13.3 0.4 2.6 2 1 0 2 2 2 1 Nup133 N terminal like WD40_like PF17005.5 KIK34394.1 - 0.0015 18.0 0.0 1.2 8.4 0.0 2.7 2 1 1 3 3 3 2 WD40-like domain PQQ_2 PF13360.6 KIK34394.1 - 0.019 14.6 2.4 0.15 11.6 0.5 2.6 2 1 0 2 2 2 0 PQQ-like domain PD40 PF07676.12 KIK34394.1 - 0.048 13.6 0.6 15 5.6 0.0 4.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PQQ PF01011.21 KIK34394.1 - 0.079 12.9 0.1 9 6.4 0.0 3.8 3 0 0 3 3 3 0 PQQ enzyme repeat WD40 PF00400.32 KIK34395.1 - 2.3e-23 82.0 16.0 7.9e-09 36.0 2.5 6.8 5 2 1 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34395.1 - 1.3e-17 63.9 0.4 0.00061 20.0 0.1 5.8 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK34395.1 - 5.2e-06 26.5 1.1 0.0033 17.3 0.2 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK34395.1 - 6.5e-06 25.3 2.5 0.34 9.8 0.0 3.6 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK34395.1 - 3.5e-05 23.6 0.0 20 5.3 0.0 5.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PQQ PF01011.21 KIK34395.1 - 3.8e-05 23.4 1.7 0.21 11.6 0.0 4.8 5 0 0 5 5 5 1 PQQ enzyme repeat PQQ_2 PF13360.6 KIK34395.1 - 0.00031 20.4 2.2 0.00078 19.1 0.7 2.3 2 1 0 2 2 2 1 PQQ-like domain Nbas_N PF15492.6 KIK34395.1 - 0.00047 19.6 0.4 0.54 9.5 0.1 4.2 2 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK34395.1 - 0.0013 17.4 1.0 0.029 13.0 0.0 2.7 2 1 0 2 2 2 1 Nucleoporin Nup120/160 SGL PF08450.12 KIK34395.1 - 0.037 13.6 0.1 0.86 9.1 0.0 2.5 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region PQQ_3 PF13570.6 KIK34395.1 - 0.065 13.7 1.5 59 4.3 1.2 4.1 4 0 0 4 4 4 0 PQQ-like domain WD40_like PF17005.5 KIK34395.1 - 0.23 10.8 0.0 8.3 5.6 0.0 2.6 2 1 1 3 3 3 0 WD40-like domain D_CNTX PF17492.2 KIK34399.1 - 0.027 14.6 5.6 0.035 14.3 5.6 1.3 1 0 0 1 1 1 0 Delta Ctenitoxins Amidase PF01425.21 KIK34401.1 - 4.7e-115 385.1 0.4 6.7e-115 384.6 0.4 1.2 1 0 0 1 1 1 1 Amidase Mito_carr PF00153.27 KIK34402.1 - 9.6e-64 211.4 2.2 2.1e-22 78.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rbc25 PF08292.12 KIK34403.1 - 6.9e-31 107.2 0.0 1.2e-30 106.4 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KIK34403.1 - 7.7e-18 64.6 0.0 1.4e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 UbiA PF01040.18 KIK34404.1 - 4.4e-41 140.8 18.2 6e-41 140.4 18.2 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Ost4 PF10215.9 KIK34404.1 - 0.12 12.2 0.1 0.12 12.2 0.1 2.3 2 0 0 2 2 2 0 Oligosaccaryltransferase UbiA PF01040.18 KIK34405.1 - 5.4e-40 137.3 22.8 9.7e-40 136.4 22.4 1.6 1 1 1 2 2 2 1 UbiA prenyltransferase family Ost4 PF10215.9 KIK34405.1 - 0.026 14.3 0.1 0.077 12.8 0.1 1.8 1 0 0 1 1 1 0 Oligosaccaryltransferase Plavaka PF18759.1 KIK34408.1 - 4.6e-14 52.4 0.1 4.6e-14 52.4 0.1 1.0 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK34409.1 - 2.5e-16 59.8 0.0 3.3e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase PurS PF02700.14 KIK34410.1 - 0.094 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase DUF1192 PF06698.11 KIK34410.1 - 0.66 10.1 3.9 0.89 9.7 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Uds1 PF15456.6 KIK34411.1 - 0.32 11.2 4.6 0.66 10.2 0.2 2.6 2 0 0 2 2 2 0 Up-regulated During Septation Sec2p PF06428.11 KIK34411.1 - 1.1 9.3 4.2 0.34 10.9 0.4 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p HR1 PF02185.16 KIK34411.1 - 1.1 9.5 6.6 0.14 12.3 1.5 2.2 2 0 0 2 2 2 0 Hr1 repeat SlyX PF04102.12 KIK34411.1 - 4.3 8.0 9.2 19 5.9 0.6 3.3 2 0 0 2 2 2 0 SlyX DUF1648 PF07853.11 KIK34413.1 - 1.1 9.0 6.5 2.6 7.8 0.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1648) DDE_3 PF13358.6 KIK34418.1 - 2e-08 34.1 0.1 2.5e-08 33.8 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KIK34419.1 - 1.1e-06 28.5 0.0 1.2e-06 28.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KIK34420.1 - 0.00045 20.4 0.0 0.00059 20.0 0.0 1.2 1 0 0 1 1 1 1 Transposase HTH_33 PF13592.6 KIK34420.1 - 0.0014 18.2 0.3 0.0019 17.8 0.3 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HK97-gp10_like PF04883.12 KIK34420.1 - 0.0064 17.4 0.1 0.0072 17.3 0.1 1.2 1 0 0 1 1 1 1 Bacteriophage HK97-gp10, putative tail-component Arg_repressor PF01316.21 KIK34420.1 - 0.0079 15.9 0.1 0.011 15.4 0.1 1.2 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain WD40 PF00400.32 KIK34423.1 - 1.5e-123 399.1 62.7 8.4e-11 42.3 0.6 14.6 14 0 0 14 14 14 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34423.1 - 4.4e-37 126.3 9.5 0.0018 18.6 0.0 12.7 1 1 12 13 13 13 10 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK34423.1 - 1e-17 64.4 0.0 0.024 14.0 0.0 10.0 9 2 1 10 10 10 4 WD40-like domain PD40 PF07676.12 KIK34423.1 - 2.4e-14 52.8 10.2 5.2 7.1 0.0 13.0 14 0 0 14 14 14 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK34423.1 - 9.5e-13 47.8 2.9 0.98 8.3 0.0 9.8 5 3 7 12 12 12 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK34423.1 - 4.1e-12 45.5 3.1 2.1 6.9 0.0 9.9 10 2 2 12 12 12 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KIK34423.1 - 3.3e-11 42.6 9.6 3.6 6.2 0.0 10.2 4 4 6 10 10 10 3 Nup133 N terminal like PQQ PF01011.21 KIK34423.1 - 1.9e-05 24.3 0.2 25 5.0 0.0 7.8 9 0 0 9 9 9 0 PQQ enzyme repeat Peptidase_S9_N PF02897.15 KIK34423.1 - 3.1e-05 22.9 1.3 33 3.1 0.0 7.4 3 3 5 8 8 8 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF4402 PF14352.6 KIK34423.1 - 0.00021 21.9 8.9 0.77 10.4 0.6 6.5 1 1 7 8 8 8 1 Domain of unknown function (DUF4402) PQQ_3 PF13570.6 KIK34423.1 - 0.0012 19.2 17.0 13 6.4 0.1 9.8 7 3 4 11 11 11 0 PQQ-like domain Frtz PF11768.8 KIK34423.1 - 0.0024 16.3 0.0 30 2.7 0.0 5.8 4 3 4 8 8 8 0 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 KIK34423.1 - 0.0073 15.7 2.5 13 5.0 0.0 5.5 5 2 0 5 5 5 0 Neuroblastoma-amplified sequence, N terminal nos_propeller PF18764.1 KIK34423.1 - 0.57 10.1 12.5 85 3.2 0.0 7.6 10 0 0 10 10 10 0 Nitrous oxide reductase propeller repeat Cuticle_4 PF15955.5 KIK34423.1 - 1.1 10.1 15.2 1.9e+02 2.9 0.0 8.3 9 1 1 10 10 10 0 Cuticle protein Antimicrobial22 PF16047.5 KIK34423.1 - 2.6 8.0 3.8 1.7 8.6 0.0 2.8 3 0 0 3 3 3 0 Frog antimicrobial peptide DHFR_2 PF06442.11 KIK34423.1 - 3.7 7.5 7.1 3.8 7.4 0.1 4.3 4 1 1 5 5 5 0 R67 dihydrofolate reductase Cpn60_TCP1 PF00118.24 KIK34424.1 - 1.1e-85 288.2 8.2 1.9e-85 287.3 8.2 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Med14 PF08638.11 KIK34425.1 - 1.4e-66 223.6 0.3 1.4e-66 223.6 0.3 1.7 2 0 0 2 2 2 1 Mediator complex subunit MED14 Lactonase PF10282.9 KIK34425.1 - 0.2 10.9 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller HET PF06985.11 KIK34427.1 - 4.6e-10 40.0 0.3 9.2e-10 39.0 0.3 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FYVE_2 PF02318.16 KIK34428.1 - 1.7 8.9 8.3 2.3 8.5 2.1 2.7 2 0 0 2 2 2 0 FYVE-type zinc finger CK_II_beta PF01214.18 KIK34428.1 - 2.7 7.8 6.7 0.9 9.3 0.8 2.3 2 0 0 2 2 2 0 Casein kinase II regulatory subunit C1_2 PF03107.16 KIK34428.1 - 5.1 7.5 12.6 2.7 8.4 1.3 3.7 4 0 0 4 4 4 0 C1 domain Na_H_Exchanger PF00999.21 KIK34429.1 - 5.8e-08 31.9 6.4 8.6e-08 31.4 6.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family UBA PF00627.31 KIK34429.1 - 0.0096 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Pyr_redox_3 PF13738.6 KIK34430.1 - 5.6e-20 71.8 0.0 2.2e-18 66.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KIK34430.1 - 9.9e-20 70.4 0.1 2.8e-17 62.3 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KIK34430.1 - 4e-18 65.7 0.4 4.3e-14 52.4 0.1 2.9 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK34430.1 - 5.3e-12 45.5 0.5 2.5e-10 40.1 0.6 2.8 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KIK34430.1 - 7.9e-09 35.5 1.0 1.5e-05 24.8 0.3 3.2 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK34430.1 - 3.6e-08 33.5 0.1 1.4e-07 31.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIK34430.1 - 2e-07 31.5 1.9 0.002 18.7 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK34430.1 - 6.5e-07 28.4 1.6 3.5e-05 22.7 0.1 2.7 4 0 0 4 4 4 1 HI0933-like protein NAD_binding_9 PF13454.6 KIK34430.1 - 1.4e-06 28.4 0.2 0.0012 18.8 0.0 2.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KIK34430.1 - 2.4e-06 27.0 1.1 3.8e-06 26.4 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 KIK34430.1 - 1.2e-05 25.3 0.5 0.00051 20.1 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KIK34430.1 - 0.00028 21.3 0.0 0.04 14.4 0.2 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KIK34430.1 - 0.0015 17.7 0.8 0.0015 17.7 0.8 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KIK34430.1 - 0.0045 16.4 0.8 0.0076 15.6 0.8 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KIK34430.1 - 0.0046 16.1 3.9 0.1 11.6 0.1 2.9 4 0 0 4 4 4 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 KIK34430.1 - 0.007 15.7 0.0 0.25 10.6 0.2 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 KIK34430.1 - 0.0095 15.3 0.1 0.031 13.6 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KIK34430.1 - 0.024 13.9 0.0 0.29 10.3 0.0 2.3 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 KIK34430.1 - 0.026 14.8 0.0 1 9.6 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Trp_halogenase PF04820.14 KIK34430.1 - 0.045 12.6 0.4 0.045 12.6 0.4 2.1 3 0 0 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.12 KIK34430.1 - 0.05 12.7 0.7 0.45 9.5 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein DUF4147 PF13660.6 KIK34430.1 - 0.14 11.7 0.0 0.95 9.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) AAA PF00004.29 KIK34431.1 - 0.00046 20.6 0.0 0.00069 20.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIK34431.1 - 0.016 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_8 PF12780.7 KIK34431.1 - 0.041 13.2 0.0 0.057 12.7 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Sigma54_activat PF00158.26 KIK34431.1 - 0.053 13.2 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 KIK34431.1 - 0.065 13.2 0.1 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE tRNA_lig_kinase PF08303.11 KIK34431.1 - 0.1 12.7 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 tRNA ligase kinase domain Sigma54_activ_2 PF14532.6 KIK34431.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RuvB_N PF05496.12 KIK34431.1 - 0.22 11.2 0.0 0.34 10.6 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain F-box-like PF12937.7 KIK34433.1 - 0.019 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 F-box-like DUF3419 PF11899.8 KIK34434.1 - 1.2e-140 469.1 0.0 1.5e-140 468.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 KIK34434.1 - 1.8e-09 37.7 0.0 7.7e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK34434.1 - 2.7e-09 37.6 0.0 1.1e-07 32.5 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK34434.1 - 4e-08 33.9 0.0 2.2e-05 25.1 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK34434.1 - 6.7e-08 33.1 0.0 2.1e-05 25.1 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK34434.1 - 4e-06 26.3 0.0 5.3e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIK34434.1 - 4.2e-05 23.4 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KIK34434.1 - 0.082 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 KIK34434.1 - 0.091 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase CHAT PF12770.7 KIK34435.1 - 7.5e-37 127.3 0.0 2.6e-36 125.5 0.0 2.0 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK34435.1 - 9.9e-22 76.1 11.9 0.077 12.9 0.0 16.0 16 2 1 17 17 17 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIK34435.1 - 9.3e-10 38.7 29.0 17 5.8 0.0 14.8 17 1 1 18 18 18 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK34435.1 - 8.1e-09 34.9 1.9 53 4.2 0.0 12.4 14 0 0 14 14 14 0 Tetratricopeptide repeat CBP_CCPA PF17040.5 KIK34435.1 - 0.0013 19.3 9.2 1.3e+02 3.2 0.0 10.0 8 2 5 14 14 14 0 Cellulose-complementing protein A TPR_11 PF13414.6 KIK34435.1 - 0.02 14.6 0.0 40 4.0 0.0 5.9 7 0 0 7 7 7 0 TPR repeat Surp PF01805.20 KIK34435.1 - 0.042 13.8 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 Surp module TPR_16 PF13432.6 KIK34435.1 - 0.35 11.5 14.2 15 6.3 0.1 7.5 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK34435.1 - 1.8 8.5 7.1 84 3.2 0.0 7.1 9 0 0 9 9 9 0 Tetratricopeptide repeat DUF3106 PF11304.8 KIK34438.1 - 0.021 15.3 1.5 0.04 14.4 0.0 2.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3106) LRR_4 PF12799.7 KIK34440.1 - 0.31 11.5 3.6 22 5.7 0.7 3.8 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Plavaka PF18759.1 KIK34441.1 - 3.5e-131 437.2 0.0 5.1e-131 436.7 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase ABC_tran PF00005.27 KIK34444.1 - 5.3e-30 104.7 0.1 9.1e-30 104.0 0.1 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIK34444.1 - 4.7e-06 26.2 1.5 0.00017 21.1 0.3 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIK34444.1 - 0.0012 18.7 0.1 0.31 10.8 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KIK34444.1 - 0.0014 18.7 0.1 0.0039 17.3 0.1 1.7 1 0 0 1 1 1 1 Helicase HerA, central domain NB-ARC PF00931.22 KIK34444.1 - 0.0049 16.1 0.1 0.11 11.7 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain AAA_5 PF07728.14 KIK34444.1 - 0.0076 16.2 0.6 0.69 9.9 0.1 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KIK34444.1 - 0.013 15.1 0.6 0.045 13.3 0.0 2.1 2 1 1 3 3 3 0 AAA domain AAA_29 PF13555.6 KIK34444.1 - 0.021 14.6 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 KIK34444.1 - 0.03 13.4 0.6 0.066 12.3 0.0 1.8 2 1 0 2 2 2 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KIK34444.1 - 0.13 12.3 0.2 0.38 10.9 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KIK34444.1 - 0.16 12.3 2.3 0.51 10.7 2.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain APH PF01636.23 KIK34445.1 - 2.7e-13 50.4 0.0 1e-12 48.5 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.23 KIK34447.1 - 6e-09 36.2 0.0 1.1e-08 35.3 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF836 PF05768.14 KIK34449.1 - 0.0048 17.3 1.2 3 8.3 0.0 2.4 2 0 0 2 2 2 2 Glutaredoxin-like domain (DUF836) WWE PF02825.20 KIK34449.1 - 0.082 13.5 0.6 10 6.8 0.0 2.3 2 0 0 2 2 2 0 WWE domain DUF5601 PF18151.1 KIK34449.1 - 0.19 12.0 0.5 13 6.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) zinc_ribbon_13 PF09855.9 KIK34449.1 - 0.43 10.8 13.6 2.1 8.6 2.9 2.3 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) CxC3 PF18804.1 KIK34449.1 - 7.1 6.5 14.3 3.5 7.5 3.0 2.4 1 1 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases adh_short PF00106.25 KIK34450.1 - 1.6e-18 66.9 0.0 5.5e-17 61.9 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK34450.1 - 3.3e-10 39.9 0.0 8e-10 38.7 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK34450.1 - 7.4e-07 29.2 0.1 4.5e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.20 KIK34450.1 - 0.03 14.4 0.0 0.069 13.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pkinase PF00069.25 KIK34451.1 - 1.1e-29 103.6 0.0 1.5e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK34451.1 - 9.1e-17 61.2 0.0 1.4e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK34451.1 - 0.00028 19.8 0.0 0.00039 19.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIK34451.1 - 0.00052 19.4 0.2 0.00081 18.8 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIK34451.1 - 0.053 12.5 0.2 0.076 11.9 0.2 1.1 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KIK34451.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1801 PF08818.11 KIK34451.1 - 0.063 13.8 0.0 0.74 10.4 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DU1801) Kinase-like PF14531.6 KIK34451.1 - 0.066 12.5 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Uricase PF01014.18 KIK34453.1 - 3.1e-70 234.5 0.3 3.5e-36 124.3 0.2 2.0 2 0 0 2 2 2 2 Uricase zf-H2C2_2 PF13465.6 KIK34454.1 - 1.2e-09 38.1 6.0 1.9e-07 31.2 0.9 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KIK34454.1 - 0.00015 22.0 23.6 0.00057 20.2 2.9 3.6 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK34454.1 - 0.00018 22.1 11.8 0.0021 18.7 2.4 4.0 4 0 0 4 4 3 2 C2H2-type zinc finger zf-met PF12874.7 KIK34454.1 - 0.00049 20.4 0.3 0.0012 19.2 0.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Zn_clus PF00172.18 KIK34454.1 - 0.0061 16.7 13.1 0.016 15.3 13.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_ribbon_SprT PF17283.2 KIK34454.1 - 0.089 12.7 5.6 0.24 11.3 5.6 1.7 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-Di19 PF05605.12 KIK34454.1 - 0.11 12.8 6.6 1.8 9.0 0.7 2.5 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KIK34454.1 - 0.2 11.7 7.6 1.6 8.8 0.5 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK34454.1 - 0.25 11.7 1.6 3.1 8.2 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 KIK34454.1 - 0.39 10.6 1.6 0.74 9.7 0.1 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 KIK34454.1 - 0.53 10.1 5.9 3 7.7 1.1 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF3466 PF11949.8 KIK34454.1 - 0.53 8.8 2.6 17 3.8 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3466) zf-C2H2_2 PF12756.7 KIK34454.1 - 0.95 9.8 9.8 0.66 10.3 0.5 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) GST_N_3 PF13417.6 KIK34459.1 - 5.3e-05 23.5 0.1 0.0001 22.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK34459.1 - 0.00039 20.6 0.0 0.00078 19.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK34459.1 - 0.00053 20.1 0.0 0.0011 19.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KIK34459.1 - 0.0016 18.7 0.0 0.0034 17.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK34459.1 - 0.0096 15.9 0.0 0.015 15.3 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cys_Met_Meta_PP PF01053.20 KIK34463.1 - 1e-11 44.0 0.0 1e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF1518 PF07469.12 KIK34465.1 - 6.5 7.2 8.5 20 5.7 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1518) WD40 PF00400.32 KIK34466.1 - 2.5e-31 107.2 30.2 1.9e-09 38.0 0.4 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34466.1 - 1.2e-12 47.9 0.3 0.0031 17.8 0.0 4.4 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK34466.1 - 0.00091 18.3 0.0 5.4 5.9 0.0 3.6 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK34466.1 - 0.029 13.0 0.6 0.64 8.6 0.0 2.8 3 1 0 3 3 3 0 Nucleoporin Nup120/160 WD40 PF00400.32 KIK34469.1 - 2e-45 151.8 18.6 2.5e-08 34.4 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34469.1 - 6.1e-13 48.9 0.2 0.16 12.3 0.0 5.3 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK34469.1 - 4.8e-07 28.8 0.1 0.0019 16.9 0.2 3.6 3 1 0 4 4 4 2 Nucleoporin Nup120/160 WW PF00397.26 KIK34469.1 - 4.7e-05 23.4 0.4 4.7e-05 23.4 0.4 2.9 3 0 0 3 3 3 1 WW domain Ge1_WD40 PF16529.5 KIK34469.1 - 0.0033 16.4 0.0 1.9 7.4 0.0 3.4 2 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK34469.1 - 0.0095 15.3 0.0 2.4 7.4 0.0 2.5 2 1 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal DUF3558 PF12079.8 KIK34469.1 - 0.023 14.7 0.9 0.36 10.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3558) Cytochrom_D1 PF02239.16 KIK34469.1 - 0.054 12.0 0.0 0.52 8.8 0.0 2.0 1 1 1 2 2 2 0 Cytochrome D1 heme domain WD40 PF00400.32 KIK34470.1 - 3.9e-22 78.1 3.5 1.5e-07 32.0 0.2 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34470.1 - 1.1e-05 25.6 0.6 0.58 10.5 0.0 3.6 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK34470.1 - 0.0012 18.2 0.0 0.019 14.3 0.0 2.4 2 1 1 3 3 3 1 WD40-like domain Nup160 PF11715.8 KIK34470.1 - 0.0017 17.1 0.0 0.013 14.2 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 PD40 PF07676.12 KIK34470.1 - 0.0067 16.3 0.1 16 5.6 0.0 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 KIK34470.1 - 0.041 13.0 0.0 10 5.1 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) KDZ PF18758.1 KIK34471.1 - 1e-83 280.4 0.0 1.8e-83 279.6 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK34471.1 - 0.11 12.6 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases zf_C2H2_10 PF18414.1 KIK34471.1 - 0.21 11.1 0.5 0.47 10.0 0.5 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger Cauli_VI PF01693.16 KIK34472.1 - 5.3e-06 26.6 0.3 8.3e-06 26.0 0.3 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF555 PF04475.12 KIK34473.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF555) SRP9-21 PF05486.12 KIK34474.1 - 0.12 12.8 1.6 0.31 11.4 1.6 1.7 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) WD40 PF00400.32 KIK34475.1 - 1.5e-08 35.2 0.1 3.8e-08 33.9 0.0 1.6 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34475.1 - 0.0015 18.8 0.0 0.0017 18.6 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain DAO PF01266.24 KIK34476.1 - 3.8e-50 171.4 0.5 6.1e-50 170.8 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KIK34476.1 - 1.8e-39 134.5 0.0 3e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_oxidored PF12831.7 KIK34476.1 - 7.3e-07 28.9 0.6 6e-06 25.9 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK34476.1 - 3.5e-06 26.4 3.4 2.6e-05 23.5 0.8 2.4 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK34476.1 - 0.0008 18.7 0.0 0.0019 17.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK34476.1 - 0.0015 18.7 0.3 0.0046 17.1 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KIK34476.1 - 0.0042 16.2 0.3 0.023 13.8 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 KIK34476.1 - 0.015 14.0 0.9 0.022 13.5 0.9 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KIK34476.1 - 0.018 15.5 0.4 0.038 14.5 0.4 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KIK34476.1 - 0.026 14.4 0.2 0.044 13.7 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KIK34476.1 - 0.088 12.0 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KIK34476.1 - 0.17 11.1 0.0 0.36 10.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IIGP PF05049.13 KIK34482.1 - 1.3e-26 93.5 0.1 6.7e-26 91.2 0.1 1.8 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KIK34482.1 - 4.6e-06 26.7 0.0 9.6e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KIK34482.1 - 8.2e-05 23.1 0.6 0.00046 20.7 0.6 2.1 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KIK34482.1 - 0.00056 19.9 0.1 0.0047 16.9 0.0 2.3 2 1 1 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 KIK34482.1 - 0.0088 15.8 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KIK34482.1 - 0.011 16.0 0.2 0.16 12.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KIK34482.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KIK34482.1 - 0.023 14.4 0.4 0.52 10.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KIK34482.1 - 0.081 13.1 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase WDCP PF15390.6 KIK34482.1 - 0.087 11.2 0.7 0.11 10.8 0.7 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family AAA_16 PF13191.6 KIK34482.1 - 0.12 12.7 0.0 0.37 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 KIK34482.1 - 0.16 12.4 0.3 0.69 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Hist_deacetyl PF00850.19 KIK34484.1 - 7.6e-82 275.2 0.0 9.5e-82 274.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DSPc PF00782.20 KIK34485.1 - 7.4e-47 158.5 0.0 5.9e-36 123.2 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KIK34485.1 - 3.8e-06 27.2 0.1 0.00094 19.5 0.0 2.5 2 0 0 2 2 2 2 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KIK34485.1 - 0.0094 15.5 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPn PF14671.6 KIK34485.1 - 0.012 16.1 0.2 3 8.3 0.0 2.3 2 0 0 2 2 2 0 Dual specificity protein phosphatase, N-terminal half YidD PF01809.18 KIK34485.1 - 0.048 13.5 0.1 1.1 9.2 0.1 2.5 2 0 0 2 2 2 0 Putative membrane protein insertion efficiency factor DUF3439 PF11921.8 KIK34485.1 - 2 8.4 7.3 6.1 6.8 7.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Metallophos PF00149.28 KIK34489.1 - 2.4e-36 126.1 0.1 3.7e-36 125.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KIK34489.1 - 0.018 15.5 0.6 0.037 14.5 0.6 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 KIK34489.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain zf-TRAF PF02176.18 KIK34491.1 - 0.1 13.3 1.8 0.4 11.4 1.7 2.1 1 1 0 1 1 1 0 TRAF-type zinc finger FOXP-CC PF16159.5 KIK34491.1 - 0.21 12.2 4.3 3.2 8.4 0.3 2.2 1 1 1 2 2 2 0 FOXP coiled-coil domain Pkinase_Tyr PF07714.17 KIK34492.1 - 1.2e-43 149.3 0.0 1.5e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK34492.1 - 2.4e-42 145.1 0.0 3e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK34492.1 - 3.1e-05 24.0 0.0 8.3e-05 22.6 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KIK34492.1 - 0.00058 19.3 0.0 0.00095 18.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK34492.1 - 0.0075 15.1 0.2 0.011 14.6 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIK34492.1 - 0.014 14.8 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 KIK34492.1 - 0.021 13.9 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 KIK34492.1 - 0.035 13.7 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family MFS_1 PF07690.16 KIK34493.1 - 1.1e-50 172.6 39.0 1.1e-50 172.6 39.0 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK34493.1 - 3.6e-17 62.0 13.7 5.3e-17 61.5 13.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIK34493.1 - 5.9e-12 45.2 13.0 5.9e-12 45.2 13.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter NAD_binding_1 PF00175.21 KIK34494.1 - 0.052 14.2 0.0 0.097 13.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain zf-C2H2 PF00096.26 KIK34495.1 - 1.1e-06 28.8 10.1 0.023 15.2 0.7 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK34495.1 - 2e-05 25.0 7.8 0.064 14.1 0.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KIK34495.1 - 0.033 13.9 7.1 1 9.2 0.8 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-TRAF PF02176.18 KIK34495.1 - 0.053 14.2 3.5 0.053 14.2 3.5 2.1 1 1 0 2 2 2 0 TRAF-type zinc finger zf-H2C2_2 PF13465.6 KIK34495.1 - 0.057 13.9 0.1 0.057 13.9 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger double domain zf-BED PF02892.15 KIK34495.1 - 2 8.5 4.6 0.91 9.6 0.2 2.2 2 0 0 2 2 2 0 BED zinc finger DUF4603 PF15376.6 KIK34496.1 - 0.022 12.2 1.5 0.027 11.9 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Plavaka PF18759.1 KIK34497.1 - 6.4e-14 51.9 0.6 1.1e-13 51.1 0.1 1.6 2 0 0 2 2 2 1 Plavaka transposase Rit1_C PF17184.4 KIK34499.1 - 6.2e-22 78.3 0.1 6.6e-22 78.2 0.1 1.0 1 0 0 1 1 1 1 Rit1 N-terminal domain Calpain_III PF01067.22 KIK34500.1 - 1.3e-12 48.1 0.2 1.1e-08 35.5 0.0 3.4 3 1 0 3 3 3 3 Calpain large subunit, domain III DUF3435 PF11917.8 KIK34503.1 - 0.084 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) MRP-L20 PF12824.7 KIK34503.1 - 0.12 12.6 2.0 0.69 10.1 2.4 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 zf-TRM13_CCCH PF11722.8 KIK34508.1 - 0.037 13.8 0.4 0.057 13.2 0.4 1.3 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein 2OG-FeII_Oxy_5 PF13759.6 KIK34508.1 - 0.043 14.2 0.0 0.046 14.1 0.0 1.1 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase zf-C2H2_4 PF13894.6 KIK34509.1 - 0.26 12.2 5.2 3 8.9 3.9 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK34509.1 - 2.3 8.8 6.3 6.4 7.4 4.4 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Sortilin-Vps10 PF15902.5 KIK34510.1 - 2.5e-129 432.0 0.2 3.3e-129 431.6 0.2 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KIK34510.1 - 1.6e-17 64.4 0.6 3.7e-17 63.2 0.6 1.5 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KIK34510.1 - 0.00012 21.5 19.2 3.5 8.0 0.1 6.7 6 0 0 6 6 6 4 BNR/Asp-box repeat CHB_HEX_C PF03174.13 KIK34510.1 - 0.095 12.7 0.7 31 4.7 0.1 4.2 5 0 0 5 5 5 0 Chitobiase/beta-hexosaminidase C-terminal domain Zn_clus PF00172.18 KIK34510.1 - 5.9 7.1 6.6 6.8 6.9 0.9 2.6 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Not1 PF04054.15 KIK34511.1 - 6.2e-22 78.0 0.3 8.4e-22 77.6 0.3 1.1 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 Ldh_1_N PF00056.23 KIK34511.1 - 7.2e-12 45.6 0.2 8.8e-12 45.3 0.2 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Gemini_C4 PF01492.17 KIK34512.1 - 0.6 10.1 3.0 12 5.8 0.2 2.5 1 1 1 2 2 2 0 Geminivirus C4 protein NST1 PF13945.6 KIK34513.1 - 1.8e-11 44.5 0.7 1.8e-11 44.5 0.7 1.9 2 0 0 2 2 2 1 Salt tolerance down-regulator Toxin_14 PF07829.11 KIK34513.1 - 0.16 11.9 1.5 0.29 11.1 1.5 1.4 1 0 0 1 1 1 0 Alpha-A conotoxin PIVA-like protein BUD22 PF09073.10 KIK34513.1 - 0.86 8.9 16.2 1.2 8.4 16.2 1.1 1 0 0 1 1 1 0 BUD22 Myc_N PF01056.18 KIK34513.1 - 1.3 8.8 13.2 1.1 9.2 3.3 2.2 2 0 0 2 2 2 0 Myc amino-terminal region TLP-20 PF06088.11 KIK34513.1 - 2.8 7.8 5.4 6.1 6.7 0.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FAM176 PF14851.6 KIK34513.1 - 4.4 7.0 16.4 6.3 6.5 3.7 2.4 2 0 0 2 2 2 0 FAM176 family Merozoite_SPAM PF07133.11 KIK34513.1 - 5.3 7.0 33.4 1.1 9.3 14.8 2.2 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) PBP1_TM PF14812.6 KIK34513.1 - 5.6 7.4 21.3 7.1 7.1 8.0 2.6 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4820 PF16091.5 KIK34513.1 - 6.2 6.1 6.4 1.4 8.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Prothymosin PF03247.14 KIK34513.1 - 9.8 6.7 39.3 0.96 9.9 18.9 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family PhoLip_ATPase_C PF16212.5 KIK34514.1 - 1.9e-19 70.4 19.8 1.3e-18 67.7 2.0 3.0 1 1 1 2 2 2 2 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 KIK34514.1 - 0.036 14.4 0.0 0.05 13.9 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SERTA PF06031.13 KIK34515.1 - 0.065 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 SERTA motif zf-CCHC PF00098.23 KIK34516.1 - 0.00062 19.7 2.3 0.0016 18.4 2.3 1.7 1 0 0 1 1 1 1 Zinc knuckle Spc7 PF08317.11 KIK34516.1 - 0.0026 16.7 7.5 0.004 16.1 7.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 KIK34516.1 - 0.0097 16.0 8.7 0.012 15.6 7.3 1.8 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus PhageMin_Tail PF10145.9 KIK34516.1 - 0.026 14.4 1.2 0.051 13.4 1.2 1.4 1 0 0 1 1 1 0 Phage-related minor tail protein Mer2 PF09074.10 KIK34516.1 - 0.084 12.7 2.6 0.14 11.9 2.6 1.4 1 0 0 1 1 1 0 Mer2 zf-CCHC_5 PF14787.6 KIK34516.1 - 0.1 12.3 3.4 0.2 11.4 3.4 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger KxDL PF10241.9 KIK34516.1 - 0.11 12.8 2.1 4.3 7.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein TPR_MLP1_2 PF07926.12 KIK34516.1 - 0.12 12.5 11.9 0.2 11.7 11.9 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 KIK34516.1 - 0.13 12.4 3.1 0.3 11.3 3.1 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FmiP_Thoc5 PF09766.9 KIK34516.1 - 0.14 11.4 4.8 0.59 9.4 2.5 2.2 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 DUF3053 PF11254.8 KIK34516.1 - 0.14 11.7 1.6 0.24 11.0 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) HOOK PF05622.12 KIK34516.1 - 0.16 10.1 5.6 0.23 9.6 5.6 1.1 1 0 0 1 1 1 0 HOOK protein Use1 PF09753.9 KIK34516.1 - 0.16 11.6 4.8 0.12 12.1 2.1 1.9 1 1 1 2 2 2 0 Membrane fusion protein Use1 Prominin PF05478.11 KIK34516.1 - 0.18 9.7 3.8 0.24 9.3 3.8 1.1 1 0 0 1 1 1 0 Prominin HrpB7 PF09486.10 KIK34516.1 - 0.29 11.5 8.8 0.54 10.6 8.8 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) GIT1_C PF12205.8 KIK34516.1 - 0.47 10.6 3.7 0.29 11.2 0.8 2.2 2 1 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term FapA PF03961.13 KIK34516.1 - 0.57 8.7 2.0 0.79 8.3 2.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 KIK34516.1 - 2 8.5 4.8 3.2 7.8 4.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HIP1_clath_bdg PF16515.5 KIK34516.1 - 2.3 8.9 8.6 3.6 8.3 6.9 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SlyX PF04102.12 KIK34516.1 - 3.8 8.2 6.6 3.9 8.2 0.1 2.8 2 1 0 2 2 2 0 SlyX CLZ PF16526.5 KIK34516.1 - 4.4 7.7 7.3 0.83 10.1 2.7 2.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Uso1_p115_C PF04871.13 KIK34516.1 - 5.4 7.4 9.9 30 5.0 9.9 2.0 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region RVT_1 PF00078.27 KIK34518.1 - 2.6e-07 30.4 0.0 3.2e-07 30.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 KIK34519.1 - 0.00076 20.1 0.3 0.0012 19.5 0.3 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF953 PF06110.11 KIK34519.1 - 0.11 12.1 0.0 0.43 10.2 0.0 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) zf-CCHC PF00098.23 KIK34520.1 - 0.34 11.1 12.0 1.2 9.4 0.1 3.6 3 1 0 3 3 3 0 Zinc knuckle RVT_1 PF00078.27 KIK34522.1 - 3.2e-08 33.3 0.0 3.6e-08 33.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 KIK34524.1 - 3.6e-05 24.4 0.3 4.7e-05 24.0 0.3 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Uricase PF01014.18 KIK34525.1 - 6.4e-06 26.5 0.0 6.5e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Uricase NAD_binding_10 PF13460.6 KIK34527.1 - 1.4e-07 31.6 0.0 0.0021 18.0 0.0 2.2 2 0 0 2 2 2 2 NAD(P)H-binding adh_short PF00106.25 KIK34527.1 - 1.6e-05 24.5 0.0 2.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase ApbA PF02558.16 KIK34527.1 - 0.002 17.8 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA adh_short_C2 PF13561.6 KIK34527.1 - 0.009 15.6 0.0 0.017 14.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pyr_redox_3 PF13738.6 KIK34527.1 - 0.036 13.3 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK34527.1 - 0.11 13.1 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Tetraspanin PF00335.20 KIK34529.1 - 6e-11 42.5 8.1 7.8e-11 42.1 8.1 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF3278 PF11683.8 KIK34529.1 - 1.4 9.0 4.2 0.3 11.2 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) DLH PF01738.18 KIK34531.1 - 2e-26 92.9 0.0 2.3e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DLH PF01738.18 KIK34532.1 - 3.3e-21 75.9 0.0 3.9e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KIK34532.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family KOW PF00467.29 KIK34533.1 - 0.00015 21.6 6.2 0.001 19.0 0.0 3.9 4 0 0 4 4 4 2 KOW motif Pkinase_fungal PF17667.1 KIK34535.1 - 1.5e-24 86.5 0.0 1.4e-14 53.7 0.2 2.1 1 1 1 2 2 2 2 Fungal protein kinase RIO1 PF01163.22 KIK34535.1 - 0.0001 21.9 0.1 0.00024 20.7 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIK34535.1 - 0.00099 19.1 0.1 0.0066 16.4 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIK34535.1 - 0.041 13.2 0.1 0.066 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein kinase domain SWIM PF04434.17 KIK34535.1 - 0.082 12.6 0.2 0.24 11.1 0.2 1.7 1 0 0 1 1 1 0 SWIM zinc finger zf-CW PF07496.15 KIK34535.1 - 0.29 11.2 1.7 1.4 9.0 0.0 2.6 3 0 0 3 3 3 0 CW-type Zinc Finger DUF4218 PF13960.6 KIK34539.1 - 5.5e-05 22.8 0.5 0.00013 21.6 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Phage_Gp17 PF17549.2 KIK34539.1 - 0.15 12.1 0.1 0.26 11.3 0.1 1.3 1 0 0 1 1 1 0 Gene Product 17 Alpha_kinase PF02816.18 KIK34545.1 - 1.3e-12 48.2 0.0 2.1e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family WD40 PF00400.32 KIK34546.1 - 1.3e-29 101.8 15.3 1.2e-06 29.2 1.1 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34546.1 - 5.7e-16 58.6 3.9 8e-06 26.1 0.1 5.3 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK34546.1 - 4.1e-07 30.1 0.1 0.0066 16.3 0.0 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KIK34546.1 - 1.5e-06 27.8 0.8 0.00069 19.0 0.0 3.6 1 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal RAB3GAP2_N PF14655.6 KIK34546.1 - 0.00013 21.4 0.1 0.00067 19.0 0.0 2.1 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Ge1_WD40 PF16529.5 KIK34546.1 - 0.00051 19.1 0.1 0.7 8.8 0.0 3.7 1 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK34546.1 - 0.00051 18.8 4.9 0.5 8.9 0.2 3.7 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KIK34546.1 - 0.005 15.4 1.9 0.83 8.1 0.6 2.8 1 1 2 3 3 3 1 Cytochrome D1 heme domain WD40_like PF17005.5 KIK34546.1 - 0.0087 15.4 0.0 0.36 10.1 0.0 2.6 2 1 1 3 3 3 1 WD40-like domain Lactonase PF10282.9 KIK34546.1 - 0.1 11.8 0.0 1.7 7.8 0.0 2.7 1 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Str_synth PF03088.16 KIK34546.1 - 0.13 12.4 0.0 12 6.1 0.0 2.9 2 1 1 3 3 3 0 Strictosidine synthase Plavaka PF18759.1 KIK34550.1 - 6.2e-31 107.8 0.0 1.2e-30 106.8 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase Phytoreo_P8 PF07124.11 KIK34551.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 Pkinase_fungal PF17667.1 KIK34552.1 - 9.7e-14 51.0 0.0 1.1e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase RcsC PF09456.10 KIK34553.1 - 0.29 11.1 1.2 11 6.1 0.1 2.3 2 0 0 2 2 2 0 RcsC Alpha-Beta-Loop (ABL) Zn_clus PF00172.18 KIK34553.1 - 0.49 10.6 7.9 1 9.5 7.9 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_12 PF13087.6 KIK34555.1 - 3.9e-18 65.8 0.1 6.9e-18 65.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain KOW PF00467.29 KIK34555.1 - 2.2e-07 30.6 14.7 0.0071 16.3 1.0 6.0 6 0 0 6 6 6 3 KOW motif Spt5_N PF11942.8 KIK34555.1 - 0.0061 17.5 0.4 0.014 16.4 0.4 1.7 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal LSM14 PF12701.7 KIK34555.1 - 0.12 12.4 0.0 12 6.1 0.0 2.6 1 1 1 2 2 2 0 Scd6-like Sm domain F-box-like PF12937.7 KIK34557.1 - 5.1e-06 26.3 0.1 2.3e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK34557.1 - 0.002 18.0 0.8 0.04 13.8 0.1 2.8 2 1 0 2 2 2 1 F-box domain WD40 PF00400.32 KIK34558.1 - 1.8e-21 76.0 15.4 4.6e-07 30.4 4.1 6.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34558.1 - 6.3e-17 61.7 1.6 1.4e-05 25.3 0.3 5.9 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KIK34558.1 - 3.9e-06 26.4 0.5 0.029 13.7 0.1 3.6 2 1 2 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK34558.1 - 8.5e-06 24.7 2.4 0.91 8.1 0.0 4.8 1 1 2 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK34558.1 - 1.8e-05 23.9 0.0 0.1 11.6 0.0 3.2 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK34558.1 - 1.9e-05 24.5 0.5 23 5.0 0.0 5.7 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KIK34558.1 - 2.9e-05 24.0 0.6 0.031 14.2 0.1 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ PF01011.21 KIK34558.1 - 0.029 14.3 0.5 73 3.5 0.0 4.0 4 0 0 4 4 4 0 PQQ enzyme repeat ABC_trans_N PF14510.6 KIK34558.1 - 0.034 14.8 0.7 0.073 13.7 0.7 1.5 1 0 0 1 1 1 0 ABC-transporter N-terminal RAB3GAP2_N PF14655.6 KIK34558.1 - 0.07 12.4 0.2 0.99 8.6 0.0 2.5 2 1 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ_3 PF13570.6 KIK34558.1 - 0.16 12.5 7.9 4.2 8.0 2.3 4.1 4 0 0 4 4 4 0 PQQ-like domain WD40_like PF17005.5 KIK34558.1 - 0.19 11.0 0.0 5.3 6.3 0.0 2.3 1 1 2 3 3 3 0 WD40-like domain DUF5122 PF17164.4 KIK34558.1 - 0.77 10.1 4.2 12 6.3 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller AhpC-TSA_2 PF13911.6 KIK34560.1 - 4.8e-14 52.4 0.0 8.2e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 KIK34560.1 - 4.8e-07 29.6 0.0 7.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KIK34560.1 - 9.1e-07 28.8 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DUF899 PF05988.12 KIK34560.1 - 0.11 12.0 1.5 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF899) Thioredoxin_8 PF13905.6 KIK34560.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Aa_trans PF01490.18 KIK34561.1 - 8.9e-89 298.0 30.8 1.1e-88 297.8 30.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pkinase_fungal PF17667.1 KIK34562.1 - 3.7e-20 72.1 0.0 4.7e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK34562.1 - 0.0016 18.4 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIK34562.1 - 0.0019 17.7 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Dimer_Tnp_hAT PF05699.14 KIK34564.1 - 8.7e-17 60.7 0.1 9.2e-17 60.6 0.1 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PhoH PF02562.16 KIK34567.1 - 0.09 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein KDZ PF18758.1 KIK34569.1 - 7.3e-32 110.8 0.1 2.8e-30 105.6 0.1 2.4 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Peptidase_C48 PF02902.19 KIK34569.1 - 1.4e-06 28.4 4.7 3.3e-06 27.1 4.7 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Plavaka PF18759.1 KIK34572.1 - 3.6e-113 378.1 0.7 4.8e-113 377.7 0.7 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-LSD1 PF06943.12 KIK34572.1 - 0.26 11.2 1.4 0.59 10.0 1.4 1.6 1 0 0 1 1 1 0 LSD1 zinc finger Aha1_N PF09229.11 KIK34575.1 - 0.95 9.7 3.6 16 5.7 0.1 3.2 2 2 1 3 3 3 0 Activator of Hsp90 ATPase, N-terminal DUF2796 PF10986.8 KIK34576.1 - 0.21 11.6 7.2 0.6 10.1 7.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Pkinase_fungal PF17667.1 KIK34577.1 - 2.6e-30 105.5 0.2 2.6e-24 85.8 0.1 2.2 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 KIK34577.1 - 7.7e-05 22.7 0.1 0.00012 22.1 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIK34577.1 - 0.0004 19.8 0.0 0.001 18.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIK34577.1 - 0.00051 19.7 0.1 0.00099 18.8 0.1 1.4 1 0 0 1 1 1 1 RIO1 family DEAD PF00270.29 KIK34578.1 - 1.3e-09 38.1 0.0 3.1e-08 33.6 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK34578.1 - 0.008 16.5 0.0 0.019 15.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SH3_13 PF18335.1 KIK34581.1 - 0.00086 19.1 0.2 0.0014 18.4 0.2 1.4 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain PIF1 PF05970.14 KIK34582.1 - 0.00029 20.1 0.0 0.00042 19.6 0.0 1.4 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIK34582.1 - 0.19 11.4 0.0 0.78 9.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.14 KIK34583.1 - 6e-07 29.0 0.0 6e-07 29.0 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIK34583.1 - 0.005 16.6 0.0 0.0061 16.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK34583.1 - 0.027 14.8 0.0 0.034 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF853 PF05872.12 KIK34583.1 - 0.12 10.9 0.1 0.15 10.6 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Helitron_like_N PF14214.6 KIK34584.1 - 2.2e-19 70.4 0.2 3.2e-18 66.6 0.2 2.3 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3605 PF12239.8 KIK34584.1 - 0.069 13.5 0.6 0.15 12.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3605) adh_short PF00106.25 KIK34586.1 - 0.00051 19.6 0.0 0.00087 18.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase DUF1634 PF07843.11 KIK34588.1 - 0.0065 16.5 1.0 0.011 15.8 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1634) DUF1011 PF06237.12 KIK34588.1 - 0.019 15.3 3.2 0.019 15.3 3.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1011) MgtE PF01769.16 KIK34588.1 - 2.2 8.7 11.5 0.15 12.5 3.9 2.3 2 1 0 2 2 2 0 Divalent cation transporter WD40 PF00400.32 KIK34592.1 - 1.2e-22 79.7 3.2 1.7e-09 38.1 0.0 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34592.1 - 4.7e-06 26.8 0.0 0.14 12.5 0.0 2.6 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK34592.1 - 0.0032 16.2 0.0 0.014 14.0 0.0 1.8 1 1 1 2 2 2 1 Nucleoporin Nup120/160 TPR_10 PF13374.6 KIK34593.1 - 1.8e-11 43.5 1.0 0.018 14.9 0.0 5.5 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK34593.1 - 9.2e-08 31.6 0.3 1.7 8.9 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK34593.1 - 2.3e-07 31.0 8.3 0.085 13.2 0.0 5.4 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIK34593.1 - 9.6e-07 28.4 2.5 2 8.3 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK34593.1 - 0.00016 21.6 0.5 1.1 9.6 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK34593.1 - 0.0023 18.6 11.9 19 6.4 0.0 7.1 6 2 2 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK34593.1 - 0.0045 16.9 7.1 5.5 7.3 0.0 5.3 4 2 1 5 5 5 2 Tetratricopeptide repeat Vta1_C PF18097.1 KIK34593.1 - 0.13 11.9 0.1 0.13 11.9 0.1 3.9 5 0 0 5 5 5 0 Vta1 C-terminal domain GDC-P PF02347.16 KIK34597.1 - 2.9e-110 369.1 1.1 1.1e-62 212.3 0.1 2.0 1 1 1 2 2 2 2 Glycine cleavage system P-protein Plavaka PF18759.1 KIK34598.1 - 1.5e-38 132.8 0.0 2.6e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase ProSAAS PF07259.12 KIK34599.1 - 0.043 13.8 1.5 0.059 13.3 1.5 1.1 1 0 0 1 1 1 0 ProSAAS precursor Ribosomal_S2 PF00318.20 KIK34599.1 - 0.14 11.4 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S2 WD40 PF00400.32 KIK34600.1 - 4.3e-29 100.2 0.8 5.4e-07 30.2 0.0 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34600.1 - 1.5e-08 34.8 0.1 0.064 13.6 0.0 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain CC PF04942.14 KIK34600.1 - 0.086 13.0 0.2 2.6 8.3 0.0 2.2 2 0 0 2 2 2 0 CC domain ubiquitin PF00240.23 KIK34601.1 - 1.5e-14 53.5 0.1 1.8e-14 53.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KIK34601.1 - 1.3e-05 25.0 0.0 1.6e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like QVR PF17064.5 KIK34602.1 - 0.075 13.3 0.3 0.1 12.8 0.3 1.5 1 1 0 1 1 1 0 Sleepless protein DDE_3 PF13358.6 KIK34605.1 - 5.2e-06 26.3 0.0 6.7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Dam PF05869.11 KIK34605.1 - 0.14 11.7 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) DDE_3 PF13358.6 KIK34606.1 - 1.7e-14 53.8 0.0 2e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 KIK34607.1 - 5.3e-08 32.4 0.2 3e-07 30.0 0.2 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KIK34607.1 - 8.7e-08 32.2 0.0 1.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 KIK34607.1 - 7.3e-06 25.9 0.1 1.9e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_1 PF01527.20 KIK34607.1 - 4.2e-05 23.8 0.0 5.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Transposase HTH_17 PF12728.7 KIK34607.1 - 0.00047 20.3 0.0 0.00099 19.2 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 KIK34607.1 - 0.00055 20.5 0.0 0.0038 17.8 0.0 1.9 1 1 1 2 2 2 1 Homeodomain-like domain HTH_36 PF13730.6 KIK34607.1 - 0.0021 18.0 0.2 0.0081 16.1 0.0 2.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_7 PF02796.15 KIK34607.1 - 0.0028 17.7 0.0 0.0074 16.3 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase Mga PF05043.13 KIK34607.1 - 0.0055 17.3 0.0 4.7 7.9 0.0 2.2 2 0 0 2 2 2 2 Mga helix-turn-helix domain HTH_AraC PF00165.23 KIK34607.1 - 0.0085 16.2 0.0 0.25 11.5 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family MarR PF01047.22 KIK34607.1 - 0.013 15.4 0.0 0.99 9.4 0.0 2.4 2 0 0 2 2 2 0 MarR family TrmB PF01978.19 KIK34607.1 - 0.013 15.3 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 KIK34607.1 - 0.017 14.9 0.0 0.057 13.2 0.0 1.9 3 0 0 3 3 3 0 IclR helix-turn-helix domain DUF3201 PF11447.8 KIK34607.1 - 0.028 13.9 0.0 0.41 10.2 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3201) HTH_3 PF01381.22 KIK34607.1 - 0.051 13.6 0.0 0.23 11.5 0.0 2.1 3 0 0 3 3 3 0 Helix-turn-helix HTH_Tnp_4 PF13613.6 KIK34607.1 - 0.064 13.0 0.1 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease Terminase_5 PF06056.12 KIK34607.1 - 0.086 12.7 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_1_2 PF13022.6 KIK34607.1 - 0.091 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_Tnp_IS630 PF01710.16 KIK34607.1 - 0.1 12.7 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Transposase LZ_Tnp_IS481 PF13011.6 KIK34607.1 - 0.1 13.1 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 CAP59_mtransfer PF11735.8 KIK34610.1 - 9.8e-69 231.7 0.0 1.3e-68 231.3 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 ABC_membrane PF00664.23 KIK34610.1 - 0.57 9.8 8.0 8.3 6.0 8.2 2.2 2 0 0 2 2 2 0 ABC transporter transmembrane region DIOX_N PF14226.6 KIK34611.1 - 2.1e-14 54.3 0.0 3.9e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK34611.1 - 0.00022 21.7 0.0 0.00068 20.1 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TM140 PF14985.6 KIK34612.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 TM140 protein family VHS PF00790.19 KIK34613.1 - 2.1e-36 124.9 0.0 7.9e-36 123.0 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 KIK34613.1 - 5.5e-20 71.5 0.4 3.9e-19 68.7 0.0 2.6 3 0 0 3 3 3 1 GAT domain GGA_N-GAT PF18308.1 KIK34613.1 - 0.0037 16.8 0.1 0.011 15.4 0.1 1.8 1 0 0 1 1 1 1 GGA N-GAT domain HR1 PF02185.16 KIK34613.1 - 0.028 14.5 1.4 0.046 13.8 0.2 1.9 2 0 0 2 2 2 0 Hr1 repeat CCDC53 PF10152.9 KIK34613.1 - 1.8 9.0 5.5 1.5 9.2 2.7 2.3 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex zf-C2H2 PF00096.26 KIK34614.1 - 8.1e-07 29.2 13.9 0.038 14.4 3.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK34614.1 - 0.00093 19.8 12.6 0.38 11.7 2.6 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KIK34614.1 - 0.0053 16.5 5.1 0.12 12.2 2.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KIK34614.1 - 0.0096 16.3 15.7 0.032 14.7 1.6 4.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_8 PF15909.5 KIK34614.1 - 0.042 14.1 7.4 1.6 9.1 0.2 2.8 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf_C2H2_ZHX PF18387.1 KIK34614.1 - 0.98 9.1 7.6 3.6 7.3 0.2 3.1 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Plavaka PF18759.1 KIK34615.1 - 5.8e-37 127.6 0.0 8.3e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase SDA1 PF05285.12 KIK34616.1 - 0.012 15.1 3.8 0.016 14.6 3.8 1.3 1 0 0 1 1 1 0 SDA1 p450 PF00067.22 KIK34619.1 - 8.9e-05 21.4 0.0 0.00012 20.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Mid1 PF12929.7 KIK34620.1 - 1.2e-06 28.0 0.0 1.4e-06 27.8 0.0 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component MFS_1 PF07690.16 KIK34621.1 - 1.1e-14 54.2 3.6 1.3e-14 53.9 3.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK34621.1 - 9.9e-06 24.7 1.1 1e-05 24.6 1.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KIK34621.1 - 0.0037 16.6 0.5 0.017 14.4 0.5 1.8 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB ZirS_C PF16583.5 KIK34621.1 - 0.049 13.2 0.0 0.57 9.7 0.1 2.2 1 1 1 2 2 2 0 Zinc-regulated secreted antivirulence protein C-terminal domain HET PF06985.11 KIK34624.1 - 4.4e-11 43.3 4.5 1.8e-08 34.8 0.6 2.1 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_1 PF00515.28 KIK34625.1 - 8.4e-09 34.9 1.2 0.75 9.7 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIK34625.1 - 3.8e-07 30.4 5.4 1.3 10.1 0.4 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK34625.1 - 1.9e-05 24.3 0.3 2.2 8.5 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK34625.1 - 0.00057 19.8 13.3 0.49 10.6 0.6 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK34625.1 - 0.0022 18.6 9.7 0.36 11.5 1.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK34625.1 - 0.0036 17.8 5.2 1 9.9 0.2 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.20 KIK34625.1 - 0.0057 16.8 0.0 1.3 9.4 0.0 3.1 3 0 0 3 3 3 1 PPR repeat TPR_11 PF13414.6 KIK34625.1 - 0.0087 15.7 0.2 0.57 9.9 0.1 3.1 3 0 0 3 3 3 1 TPR repeat MIT PF04212.18 KIK34625.1 - 0.012 15.6 1.8 2.8 8.1 0.1 3.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain PPR_2 PF13041.6 KIK34625.1 - 0.03 14.5 0.0 2.7 8.3 0.0 2.6 3 0 0 3 3 3 0 PPR repeat family BTAD PF03704.17 KIK34625.1 - 0.11 13.0 6.8 3.8 7.9 0.1 3.6 2 2 2 4 4 4 0 Bacterial transcriptional activator domain NRBF2_MIT PF17169.4 KIK34625.1 - 0.15 12.3 2.4 7.4 6.9 0.1 3.0 3 0 0 3 3 3 0 MIT domain of nuclear receptor-binding factor 2 WD40 PF00400.32 KIK34626.1 - 1.4e-42 142.9 9.0 4.1e-08 33.7 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34626.1 - 9.7e-16 57.9 0.0 6.7e-05 23.1 0.0 5.1 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK34626.1 - 2e-06 27.9 0.0 0.079 12.8 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK34626.1 - 5.1e-06 25.7 0.3 0.054 12.4 0.1 3.8 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Big_7 PF17957.1 KIK34626.1 - 0.0019 18.9 0.6 0.2 12.5 0.1 3.4 3 1 0 3 3 3 1 Bacterial Ig domain Nucleoporin_N PF08801.11 KIK34626.1 - 0.0045 15.8 0.0 0.65 8.7 0.0 2.5 2 1 0 2 2 2 2 Nup133 N terminal like Nup160 PF11715.8 KIK34626.1 - 0.034 12.8 0.1 1 7.9 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.12 KIK34626.1 - 0.044 13.7 0.0 9.5 6.3 0.0 4.1 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat F-box PF00646.33 KIK34628.1 - 0.0021 17.9 0.2 0.0053 16.6 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK34628.1 - 0.0027 17.6 1.7 0.0036 17.2 0.3 1.9 2 0 0 2 2 2 1 F-box-like CLZ PF16526.5 KIK34629.1 - 6.2e-05 23.3 1.9 0.00019 21.7 0.7 2.1 1 1 1 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc7 PF08317.11 KIK34629.1 - 6.4e-05 22.0 0.5 8.8e-05 21.5 0.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein HOOK PF05622.12 KIK34629.1 - 0.00058 18.2 1.4 0.00078 17.7 1.4 1.1 1 0 0 1 1 1 1 HOOK protein DUF5082 PF16888.5 KIK34629.1 - 0.0022 18.3 0.4 0.004 17.4 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) Ax_dynein_light PF10211.9 KIK34629.1 - 0.0039 17.2 0.8 0.0059 16.6 0.8 1.2 1 0 0 1 1 1 1 Axonemal dynein light chain AAA_13 PF13166.6 KIK34629.1 - 0.0067 15.1 1.5 0.0086 14.8 1.5 1.0 1 0 0 1 1 1 1 AAA domain Fib_alpha PF08702.10 KIK34629.1 - 0.018 15.2 1.5 0.03 14.5 1.5 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ApoLp-III PF07464.11 KIK34629.1 - 0.019 15.1 5.6 0.029 14.5 5.6 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 KIK34629.1 - 0.021 14.9 9.4 0.057 13.5 9.4 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mer2 PF09074.10 KIK34629.1 - 0.035 13.9 1.4 0.054 13.3 1.4 1.2 1 0 0 1 1 1 0 Mer2 UPF0242 PF06785.11 KIK34629.1 - 0.036 14.2 1.4 0.052 13.6 1.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HIP1_clath_bdg PF16515.5 KIK34629.1 - 0.044 14.4 5.1 0.18 12.4 3.4 2.4 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Vps54_N PF10475.9 KIK34629.1 - 0.054 12.8 1.3 0.14 11.4 0.5 1.9 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Use1 PF09753.9 KIK34629.1 - 0.058 13.1 3.5 0.19 11.4 1.0 2.0 1 1 1 2 2 2 0 Membrane fusion protein Use1 Vps53_N PF04100.12 KIK34629.1 - 0.069 12.1 1.8 0.093 11.7 1.8 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal IFT57 PF10498.9 KIK34629.1 - 0.078 11.9 0.9 0.11 11.5 0.9 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DHR10 PF18595.1 KIK34629.1 - 0.081 13.0 3.5 0.096 12.7 2.7 1.4 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Prefoldin PF02996.17 KIK34629.1 - 0.089 12.7 2.5 0.24 11.3 0.7 2.3 1 1 1 2 2 2 0 Prefoldin subunit Rogdi_lz PF10259.9 KIK34629.1 - 0.094 12.2 11.3 0.067 12.6 8.5 2.0 1 1 1 2 2 2 0 Rogdi leucine zipper containing protein DUF1664 PF07889.12 KIK34629.1 - 0.099 12.7 1.8 0.22 11.6 1.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) MSC PF09402.10 KIK34629.1 - 0.11 12.0 0.2 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain COG5 PF10392.9 KIK34629.1 - 0.12 12.5 5.1 1.1 9.4 0.3 2.7 1 1 2 3 3 3 0 Golgi transport complex subunit 5 MtrB PF05440.12 KIK34629.1 - 0.13 12.7 0.8 2.1 8.8 0.2 2.3 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Apolipoprotein PF01442.18 KIK34629.1 - 0.14 12.0 7.9 0.47 10.3 7.9 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain CENP-F_leu_zip PF10473.9 KIK34629.1 - 0.2 11.7 4.7 0.25 11.4 2.8 1.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 KIK34629.1 - 0.31 11.1 6.9 0.35 10.9 1.0 2.4 1 1 1 2 2 2 0 Laminin Domain II Jnk-SapK_ap_N PF09744.9 KIK34629.1 - 0.34 11.1 3.1 0.67 10.2 3.1 1.4 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 BORCS6 PF10157.9 KIK34629.1 - 0.4 10.9 4.2 1.4 9.1 0.3 2.3 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 6 DUF2203 PF09969.9 KIK34629.1 - 0.56 10.9 2.0 1.5 9.6 1.7 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF1993 PF09351.10 KIK34629.1 - 1.2 9.2 4.6 1.8 8.7 3.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) DUF4763 PF15960.5 KIK34629.1 - 1.5 8.1 4.8 3.7 6.8 4.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) NPV_P10 PF05531.12 KIK34629.1 - 2.4 8.7 8.5 0.62 10.6 0.6 2.8 3 1 0 4 4 2 0 Nucleopolyhedrovirus P10 protein zf-RVT PF13966.6 KIK34633.1 - 0.00051 20.7 0.2 0.00069 20.3 0.2 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase F-box-like PF12937.7 KIK34634.1 - 0.024 14.5 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 F-box-like ADH_N PF08240.12 KIK34638.1 - 1e-20 73.7 0.6 2e-20 72.7 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK34638.1 - 6.1e-15 55.4 0.1 3.3e-14 53.0 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KIK34638.1 - 0.00013 21.3 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KIK34638.1 - 0.0011 18.4 0.1 0.0019 17.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KIK34638.1 - 0.021 14.7 0.1 0.037 13.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 KIK34638.1 - 0.078 13.5 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain ThiF PF00899.21 KIK34638.1 - 0.11 11.8 0.2 0.21 10.9 0.2 1.3 1 0 0 1 1 1 0 ThiF family Fer4_6 PF12837.7 KIK34638.1 - 0.22 11.6 1.2 0.42 10.8 1.2 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain Oxidored_molyb PF00174.19 KIK34639.1 - 1.1e-51 174.8 0.0 2.3e-51 173.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KIK34639.1 - 4.9e-14 52.5 0.6 3.4e-13 49.8 0.6 2.3 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain BNR PF02012.20 KIK34639.1 - 0.017 15.0 0.5 0.13 12.4 0.1 2.7 2 0 0 2 2 2 0 BNR/Asp-box repeat Big_7 PF17957.1 KIK34639.1 - 0.034 14.9 0.1 0.08 13.7 0.1 1.6 1 0 0 1 1 1 0 Bacterial Ig domain Cpn60_TCP1 PF00118.24 KIK34640.1 - 1.2e-153 512.3 1.0 1.4e-153 512.1 1.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Metallophos PF00149.28 KIK34641.1 - 6.9e-36 124.7 0.7 9.4e-36 124.2 0.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KIK34641.1 - 0.00059 20.2 0.1 0.0012 19.2 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 KIK34641.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF5378 PF17349.2 KIK34641.1 - 0.19 11.0 0.0 0.83 8.9 0.0 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5378) IF4E PF01652.18 KIK34643.1 - 2.1e-53 180.3 0.0 3.3e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF1102 PF06510.11 KIK34643.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1102) MFS_1 PF07690.16 KIK34646.1 - 1.5e-17 63.6 52.0 1.2e-13 50.8 37.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily SpoVAB PF13782.6 KIK34646.1 - 6.4 7.1 10.4 1.2 9.4 2.6 3.1 2 2 0 2 2 2 0 Stage V sporulation protein AB MFS_1 PF07690.16 KIK34648.1 - 3.2e-11 42.8 59.1 4e-11 42.4 45.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CHAT PF12770.7 KIK34649.1 - 1.8e-34 119.5 0.0 2e-34 119.3 0.0 1.0 1 0 0 1 1 1 1 CHAT domain Peptidase_C25 PF01364.18 KIK34649.1 - 0.0067 15.7 0.0 0.0077 15.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C25 DUF2773 PF10971.8 KIK34649.1 - 0.039 14.1 0.1 5.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2773) WD40 PF00400.32 KIK34651.1 - 0.0019 19.0 0.3 0.0055 17.5 0.2 1.7 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.8 KIK34651.1 - 0.016 13.9 0.1 0.016 13.9 0.1 1.0 1 0 0 1 1 1 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KIK34652.1 - 0.0033 17.7 0.0 0.021 15.1 0.0 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain RasGEF PF00617.19 KIK34653.1 - 4.6e-27 95.4 0.0 8.8e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KIK34653.1 - 3.7e-12 46.4 0.0 1e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 KIK34653.1 - 0.00083 19.0 0.0 0.015 14.9 0.0 2.2 2 0 0 2 2 2 1 Ras family AAA_33 PF13671.6 KIK34653.1 - 0.11 12.6 0.4 0.39 10.9 0.0 2.1 3 0 0 3 3 3 0 AAA domain Plavaka PF18759.1 KIK34655.1 - 1.9e-27 96.4 0.5 3.9e-27 95.3 0.0 1.7 2 0 0 2 2 2 1 Plavaka transposase EST1 PF10374.9 KIK34655.1 - 1.5 9.4 6.6 0.29 11.8 1.1 2.4 2 1 0 2 2 2 0 Telomerase activating protein Est1 Pentapeptide PF00805.22 KIK34656.1 - 0.12 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) VbhA PF18495.1 KIK34658.1 - 0.064 13.1 0.8 0.4 10.6 0.0 2.2 2 0 0 2 2 2 0 Antitoxin VbhA HET PF06985.11 KIK34659.1 - 5.1e-11 43.1 4.4 7.4e-11 42.6 0.7 2.3 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF2330 PF10092.9 KIK34659.1 - 0.1 11.7 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) zf-UDP PF14569.6 KIK34660.1 - 2.2 8.5 11.7 1.8 8.7 0.4 2.8 2 1 1 3 3 3 0 Zinc-binding RING-finger FYVE PF01363.21 KIK34660.1 - 5.1 7.3 13.6 1.4e+02 2.7 13.6 2.5 1 1 0 1 1 1 0 FYVE zinc finger Peptidase_M28 PF04389.17 KIK34661.1 - 6.3e-36 123.9 0.0 2.1e-35 122.2 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M42 PF05343.14 KIK34661.1 - 0.0028 16.7 0.0 0.0046 16.0 0.0 1.2 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 KIK34661.1 - 0.01 15.5 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 SGS PF05002.15 KIK34661.1 - 0.16 12.1 0.7 0.38 10.9 0.0 1.9 2 0 0 2 2 2 0 SGS domain AvrRpt-cleavage PF05627.11 KIK34662.1 - 3.2e-06 26.4 2.5 2.5 7.5 0.0 4.7 4 0 0 4 4 4 2 Cleavage site for pathogenic type III effector avirulence factor Avr PriCT_2 PF08707.11 KIK34662.1 - 8.9e-05 22.8 0.4 11 6.4 0.0 4.0 3 1 1 4 4 4 1 Primase C terminal 2 (PriCT-2) DUF1031 PF06275.11 KIK34662.1 - 0.00033 20.8 0.0 16 5.9 0.0 3.9 3 1 1 4 4 4 1 Protein of unknown function (DUF1031) DUF3361 PF11841.8 KIK34662.1 - 0.0004 20.4 0.8 0.79 9.6 0.0 3.3 1 1 2 3 3 3 1 Domain of unknown function (DUF3361) DSPc PF00782.20 KIK34662.1 - 0.0054 16.6 0.0 21 5.0 0.0 3.6 2 1 2 4 4 4 0 Dual specificity phosphatase, catalytic domain tRNA_int_end_N2 PF12928.7 KIK34662.1 - 0.0069 16.5 0.0 0.95 9.7 0.0 3.1 2 1 2 4 4 4 1 tRNA-splicing endonuclease subunit sen54 N-term Exo70 PF03081.15 KIK34662.1 - 0.086 11.9 0.2 7.8 5.4 0.0 2.8 1 1 2 3 3 3 0 Exo70 exocyst complex subunit Imm74 PF15603.6 KIK34662.1 - 0.11 12.7 0.1 62 3.9 0.0 3.4 4 0 0 4 4 4 0 Immunity protein 74 GBP_repeat PF02526.14 KIK34662.1 - 0.12 12.2 1.5 80 3.1 0.0 3.8 4 0 0 4 4 4 0 Glycophorin-binding protein NdhS PF11623.8 KIK34662.1 - 0.31 10.7 1.2 15 5.4 0.0 3.2 4 0 0 4 4 4 0 NAD(P)H dehydrogenase subunit S AAA PF00004.29 KIK34664.1 - 4.3e-26 91.9 0.0 7.2e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 KIK34664.1 - 2.3e-16 59.7 0.1 8e-16 58.0 0.0 1.9 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.17 KIK34664.1 - 7.9e-10 38.4 0.0 1.8e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 SNF5 PF04855.12 KIK34664.1 - 3.5e-06 27.0 0.0 5.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 RuvB_N PF05496.12 KIK34664.1 - 4.8e-06 26.4 0.0 9.2e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KIK34664.1 - 2.1e-05 24.7 0.0 5.6e-05 23.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.14 KIK34664.1 - 3.7e-05 23.9 0.0 6.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KIK34664.1 - 0.0011 19.3 0.0 0.074 13.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KIK34664.1 - 0.0011 18.9 0.0 0.0043 17.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KIK34664.1 - 0.0017 17.6 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 KIK34664.1 - 0.014 15.8 0.0 0.25 11.7 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 KIK34664.1 - 0.015 15.3 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KIK34664.1 - 0.018 14.4 0.2 0.035 13.5 0.2 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 KIK34664.1 - 0.055 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIK34664.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KIK34664.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK34664.1 - 0.098 13.2 0.0 0.37 11.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 KIK34664.1 - 0.13 12.6 0.0 0.38 11.2 0.0 1.7 2 0 0 2 2 1 0 RNA helicase Zeta_toxin PF06414.12 KIK34664.1 - 0.13 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Plavaka PF18759.1 KIK34667.1 - 4.7e-22 78.6 0.1 1.4e-20 73.8 0.0 2.7 2 1 0 2 2 2 1 Plavaka transposase HNH_2 PF13391.6 KIK34667.1 - 0.071 13.3 0.1 19 5.5 0.1 2.9 2 0 0 2 2 2 0 HNH endonuclease Sigma70_ner PF04546.13 KIK34667.1 - 0.52 10.2 10.9 1.2 9.0 10.9 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Lactamase_B_2 PF12706.7 KIK34668.1 - 4.8e-07 29.5 0.3 1.7e-06 27.7 0.2 1.8 2 1 0 2 2 2 1 Beta-lactamase superfamily domain DRMBL PF07522.14 KIK34668.1 - 0.0026 17.9 0.0 0.0055 16.9 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 KIK34668.1 - 0.0038 17.3 1.3 0.012 15.7 1.3 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily PilP PF04351.13 KIK34669.1 - 0.081 12.9 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Pilus assembly protein, PilP AcMNPV_Ac109 PF05054.12 KIK34669.1 - 0.21 10.6 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein WD40 PF00400.32 KIK34670.1 - 2.1e-32 110.6 13.7 1.4e-05 25.8 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34670.1 - 1.9e-10 40.9 0.9 0.052 13.8 0.0 4.2 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK34670.1 - 7.8e-06 25.9 0.6 0.32 10.9 0.4 2.9 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK34670.1 - 0.00036 19.6 0.1 1.2 8.0 0.0 3.5 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK34670.1 - 0.0097 15.3 0.0 1.7 7.9 0.0 2.9 3 1 0 3 3 3 1 WD40-like domain Nbas_N PF15492.6 KIK34670.1 - 0.086 12.2 1.4 4.2 6.6 0.0 3.4 2 1 3 5 5 5 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK34670.1 - 0.35 9.5 5.2 9.7 4.7 0.1 3.5 1 1 1 3 3 3 0 Nucleoporin Nup120/160 DUF5580 PF17743.1 KIK34671.1 - 0.013 14.1 0.0 0.013 14.0 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) DNA_ligase_aden PF01653.18 KIK34671.1 - 0.041 13.0 0.0 0.042 12.9 0.0 1.0 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain HET PF06985.11 KIK34672.1 - 4.5e-06 27.1 2.2 0.0033 17.8 0.1 2.5 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) THB PF18362.1 KIK34673.1 - 0.051 13.2 0.1 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 Tri-helix bundle domain GST_N_3 PF13417.6 KIK34674.1 - 1.1e-12 48.2 0.0 2.1e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK34674.1 - 6.3e-08 32.8 0.0 1.1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK34674.1 - 7.5e-05 22.7 0.1 0.00015 21.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KIK34674.1 - 0.034 14.5 0.0 0.19 12.1 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KIK34674.1 - 0.042 14.6 0.0 0.55 11.0 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain p450 PF00067.22 KIK34675.1 - 9.5e-61 205.9 0.0 2e-60 204.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DDE_Tnp_4 PF13359.6 KIK34679.1 - 4.1e-11 42.8 0.1 4.7e-11 42.6 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KIK34679.1 - 0.041 13.5 0.0 0.041 13.5 0.0 1.1 1 0 0 1 1 1 0 Plant transposon protein ISET-FN3_linker PF16625.5 KIK34680.1 - 2.5 8.7 8.3 2.6 8.6 2.5 2.6 2 0 0 2 2 2 0 Unstructured linking region I-set and fnIII on Brother of CDO DDE_3 PF13358.6 KIK34681.1 - 0.00027 20.7 0.0 0.00034 20.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease YebO PF13974.6 KIK34682.1 - 0.0098 15.9 0.2 0.017 15.2 0.2 1.4 1 0 0 1 1 1 1 YebO-like protein NPV_P10 PF05531.12 KIK34682.1 - 0.016 15.7 1.0 0.034 14.6 1.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Phage_TTP_11 PF16460.5 KIK34683.1 - 0.14 12.0 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Phage tail tube, TTP, lambda-like HET PF06985.11 KIK34684.1 - 3.5e-11 43.6 4.0 2.7e-10 40.8 0.6 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MMR_HSR1 PF01926.23 KIK34687.1 - 5.7e-05 23.2 0.0 9.9e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KIK34687.1 - 0.00017 21.1 0.0 0.00032 20.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KIK34687.1 - 0.0025 17.7 0.0 0.49 10.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 KIK34687.1 - 0.0045 16.3 0.0 1.8 7.8 0.0 2.1 2 0 0 2 2 2 2 Septin Roc PF08477.13 KIK34687.1 - 0.0055 16.9 0.0 0.013 15.7 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KIK34687.1 - 0.0072 15.8 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein GTP_EFTU PF00009.27 KIK34687.1 - 0.0097 15.5 0.0 2.3 7.7 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ATP-synt_ab PF00006.25 KIK34687.1 - 0.03 14.0 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain G-alpha PF00503.20 KIK34687.1 - 0.067 12.3 0.2 0.4 9.8 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 KIK34687.1 - 0.08 12.7 0.0 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 KIK34687.1 - 0.12 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Asp PF00026.23 KIK34688.1 - 2e-38 132.6 4.9 2.7e-38 132.2 4.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease WD40 PF00400.32 KIK34689.1 - 8.7e-30 102.4 15.5 2.3e-08 34.5 0.4 8.3 9 0 0 9 9 7 4 WD domain, G-beta repeat TPR_2 PF07719.17 KIK34689.1 - 2.2e-11 42.9 7.4 0.15 12.2 0.1 8.3 10 0 0 10 10 7 3 Tetratricopeptide repeat HET PF06985.11 KIK34689.1 - 8.2e-11 42.4 2.4 1e-09 38.9 2.3 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ANAPC4_WD40 PF12894.7 KIK34689.1 - 2.8e-10 40.3 0.2 0.13 12.6 0.0 5.9 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain TPR_1 PF00515.28 KIK34689.1 - 1.3e-09 37.5 2.1 0.15 11.9 0.0 6.9 7 0 0 7 7 6 2 Tetratricopeptide repeat eIF2A PF08662.11 KIK34689.1 - 1.2e-05 25.3 0.0 0.66 9.8 0.0 3.4 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A TPR_7 PF13176.6 KIK34689.1 - 3.4e-05 23.6 0.5 33 4.8 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK34689.1 - 0.00012 21.7 1.0 0.021 14.5 0.5 3.3 2 0 0 2 2 2 1 TPR repeat Ge1_WD40 PF16529.5 KIK34689.1 - 0.0034 16.4 0.0 0.046 12.7 0.0 2.9 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_14 PF13428.6 KIK34689.1 - 0.0057 17.4 3.8 28 5.9 0.0 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 KIK34689.1 - 0.0083 16.2 1.3 0.24 11.5 0.0 3.2 4 0 0 4 4 4 1 Domain of Unknown Function (DUF3856) BTAD PF03704.17 KIK34689.1 - 0.014 15.8 4.9 1.8 9.0 0.1 3.5 3 1 0 4 4 3 0 Bacterial transcriptional activator domain PD40 PF07676.12 KIK34689.1 - 0.052 13.5 0.0 30 4.7 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat TPR_6 PF13174.6 KIK34689.1 - 0.086 13.5 1.1 55 4.7 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK34689.1 - 0.11 13.2 6.4 16 6.3 0.6 4.9 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIK34689.1 - 0.13 12.6 6.4 51 4.3 2.4 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat Nup160 PF11715.8 KIK34689.1 - 0.15 10.6 1.6 8 5.0 0.1 2.8 3 0 0 3 3 3 0 Nucleoporin Nup120/160 HET PF06985.11 KIK34692.1 - 1.1e-26 93.9 0.0 1.8e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pyridox_oxase_2 PF12766.7 KIK34693.1 - 4.2e-18 65.8 0.0 8.2e-18 64.9 0.0 1.5 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 KIK34693.1 - 0.0012 19.0 0.0 0.0021 18.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Transp_cyt_pur PF02133.15 KIK34694.1 - 1.4e-27 96.6 34.0 2.9e-27 95.6 34.0 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin cEGF PF12662.7 KIK34696.1 - 0.23 11.4 1.1 0.39 10.7 1.1 1.4 1 0 0 1 1 1 0 Complement Clr-like EGF-like ABC_tran PF00005.27 KIK34697.1 - 1.5e-20 74.1 0.0 2.5e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KIK34697.1 - 1.6e-10 40.6 16.8 2.9e-10 39.8 16.8 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 KIK34697.1 - 7.4e-09 35.8 1.2 0.0013 18.6 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIK34697.1 - 0.0028 18.2 1.3 0.005 17.4 1.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIK34697.1 - 0.02 14.6 0.5 0.045 13.5 0.5 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 KIK34697.1 - 0.027 13.9 0.9 5.1 6.5 0.5 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 KIK34697.1 - 0.053 13.1 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KIK34697.1 - 0.08 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Amino_oxidase PF01593.24 KIK34698.1 - 0.0091 15.3 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DUF4051 PF13260.6 KIK34698.1 - 0.027 14.2 0.1 0.057 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) OPT PF03169.15 KIK34699.1 - 2.4e-41 142.1 1.0 2.7e-41 141.9 1.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Kelch_3 PF13415.6 KIK34701.1 - 4e-18 65.2 0.4 1.3e-08 34.9 0.0 2.5 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_4 PF13418.6 KIK34701.1 - 4.7e-13 48.9 4.8 4.3e-07 29.8 0.1 3.8 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KIK34701.1 - 5.7e-13 48.6 1.0 2.9e-05 24.2 0.1 2.4 1 1 1 2 2 2 2 Kelch motif Kelch_1 PF01344.25 KIK34701.1 - 7.4e-11 41.5 6.6 5.3e-05 22.7 0.3 3.1 2 1 0 2 2 2 2 Kelch motif Kelch_2 PF07646.15 KIK34701.1 - 7.6e-06 25.7 10.6 0.0007 19.5 2.1 3.3 2 2 0 2 2 2 2 Kelch motif Kelch_5 PF13854.6 KIK34701.1 - 0.0075 16.2 1.4 2.9 8.0 0.0 3.2 4 0 0 4 4 4 2 Kelch motif BAG PF02179.16 KIK34702.1 - 0.00036 20.9 0.1 0.00082 19.8 0.1 1.5 1 0 0 1 1 1 1 BAG domain WD40 PF00400.32 KIK34703.1 - 5.6e-13 49.2 3.5 0.00043 21.0 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat WD40 PF00400.32 KIK34707.1 - 0.00024 21.8 0.9 0.0018 19.1 0.0 2.6 3 1 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34707.1 - 0.01 16.1 0.1 2.8 8.3 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain RelB_N PF18506.1 KIK34709.1 - 0.053 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 RelB Antitoxin alpha helical domain Pkinase PF00069.25 KIK34710.1 - 3.2e-53 180.8 0.0 4.3e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK34710.1 - 3.3e-19 69.2 0.1 6.2e-19 68.3 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK34710.1 - 0.0033 17.4 0.0 0.0095 15.9 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK34710.1 - 0.013 15.1 0.4 0.029 14.0 0.4 1.5 1 1 0 1 1 1 0 RIO1 family ABC1 PF03109.16 KIK34710.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Fasciclin PF02469.22 KIK34711.1 - 5.9e-27 94.4 0.0 4.5e-15 56.0 0.0 2.6 3 0 0 3 3 3 2 Fasciclin domain ATP-synt_ab PF00006.25 KIK34712.1 - 8.4e-108 358.9 0.0 1.2e-107 358.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KIK34712.1 - 4.9e-43 145.9 0.0 8.7e-43 145.0 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KIK34712.1 - 5.6e-15 55.6 4.8 1.3e-14 54.4 4.8 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 KIK34713.1 - 9.3e-41 139.3 0.0 4.1e-40 137.2 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BCDHK_Adom3 PF10436.9 KIK34713.1 - 2e-36 125.2 0.0 3.8e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KIK34713.1 - 1.4e-07 32.0 0.0 4.5e-05 23.9 0.0 2.6 1 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_lid_3 PF17862.1 KIK34713.1 - 6.9e-06 25.8 0.1 1.8e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KIK34713.1 - 0.00018 21.5 0.0 0.00052 20.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) HATPase_c_3 PF13589.6 KIK34713.1 - 0.00037 20.3 0.0 0.00075 19.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_22 PF13401.6 KIK34713.1 - 0.0004 20.7 0.0 0.01 16.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 KIK34713.1 - 0.00088 19.4 0.0 0.0021 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KIK34713.1 - 0.0024 17.1 0.0 0.0042 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 KIK34713.1 - 0.0041 17.5 0.1 0.031 14.7 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 KIK34713.1 - 0.018 15.3 0.0 0.061 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KIK34713.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KIK34713.1 - 0.032 13.7 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KIK34713.1 - 0.042 14.0 0.0 0.085 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KIK34713.1 - 0.086 12.0 0.2 0.26 10.5 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_3 PF07726.11 KIK34713.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KIK34713.1 - 0.14 11.5 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI BCAS2 PF05700.11 KIK34713.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) IstB_IS21 PF01695.17 KIK34713.1 - 0.16 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 KIK34713.1 - 0.19 11.9 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Phlebovirus_NSM PF07246.11 KIK34713.1 - 0.27 10.6 0.4 0.5 9.7 0.4 1.4 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M NUDIX PF00293.28 KIK34714.1 - 1.1e-10 41.6 0.0 1.7e-10 41.0 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain Pkinase_Tyr PF07714.17 KIK34715.1 - 5.4e-28 98.0 0.0 6.1e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK34715.1 - 2.3e-22 79.6 0.0 2.6e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KIK34715.1 - 0.024 13.9 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KIK34715.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KIK34715.1 - 0.22 11.1 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family NUDIX PF00293.28 KIK34716.1 - 4.2e-12 46.2 0.0 7.8e-12 45.4 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain MARVEL PF01284.23 KIK34717.1 - 2.8e-08 33.9 15.1 5.3e-08 33.0 15.1 1.5 1 0 0 1 1 1 1 Membrane-associating domain MIG-14_Wnt-bd PF06664.12 KIK34717.1 - 0.0012 18.1 0.7 0.0023 17.2 0.4 1.4 1 1 0 1 1 1 1 Wnt-binding factor required for Wnt secretion SLC3A2_N PF16028.5 KIK34717.1 - 0.3 10.7 1.8 0.75 9.4 1.8 1.6 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus DUF2207 PF09972.9 KIK34717.1 - 8.3 5.0 6.6 2.4 6.8 3.5 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TMF_TATA_bd PF12325.8 KIK34718.1 - 0.017 15.3 1.8 0.027 14.7 1.1 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Aminotran_3 PF00202.21 KIK34719.1 - 8.1e-44 149.9 0.0 2.1e-41 141.9 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.6 KIK34719.1 - 3.4e-16 59.7 0.0 7.2e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KIK34719.1 - 0.097 12.7 0.0 0.26 11.3 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain IlvN PF07991.12 KIK34720.1 - 9.3e-47 158.7 0.1 1.8e-46 157.7 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KIK34720.1 - 7.2e-39 133.4 0.0 1.1e-38 132.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F-box-like PF12937.7 KIK34721.1 - 0.00067 19.5 0.0 0.0019 18.0 0.0 1.8 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 KIK34723.1 - 4e-128 413.6 46.9 2e-10 41.1 0.3 14.7 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34723.1 - 4e-45 152.0 0.0 0.0024 18.1 0.0 14.2 1 1 12 14 14 14 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK34723.1 - 1.8e-30 106.1 13.9 0.0042 16.1 0.0 13.8 7 4 7 14 14 14 9 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK34723.1 - 2.2e-17 62.5 31.3 0.31 11.0 0.0 13.5 15 0 0 15 15 15 8 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK34723.1 - 5.3e-12 45.2 4.0 3.6 6.1 0.0 10.2 8 2 4 12 12 12 3 Nucleoporin Nup120/160 Peptidase_S9_N PF02897.15 KIK34723.1 - 1.1e-06 27.8 0.0 1.4 7.7 0.0 5.8 5 2 1 6 6 6 1 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF4072 PF13284.6 KIK34723.1 - 1.6e-06 28.5 1.7 27 5.3 0.0 7.9 9 0 0 9 9 9 0 Domain of unknown function (DUF4072) WD40_like PF17005.5 KIK34723.1 - 2e-06 27.4 0.0 1.1 8.5 0.0 6.5 6 1 1 7 7 7 1 WD40-like domain Nbas_N PF15492.6 KIK34723.1 - 3.4e-06 26.6 13.9 4.7 6.4 0.0 10.2 10 3 2 12 12 12 1 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 KIK34723.1 - 1.5e-05 23.5 0.0 7.7 4.7 0.0 6.3 2 2 3 6 6 6 1 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 KIK34723.1 - 0.0076 14.8 0.4 0.5 8.9 0.0 3.4 4 1 1 5 5 5 1 Cytochrome D1 heme domain PQQ_2 PF13360.6 KIK34723.1 - 0.065 12.8 19.2 1.5 8.3 9.0 4.7 1 1 2 3 3 3 0 PQQ-like domain DUF5643 PF18705.1 KIK34723.1 - 0.52 10.3 1.3 67 3.5 0.0 4.9 7 0 0 7 7 7 0 Family of unknown function (DUF5643) WD40_3 PF15911.5 KIK34723.1 - 0.67 10.0 9.6 88 3.2 0.0 7.8 11 0 0 11 11 11 0 WD domain, G-beta repeat Cuticle_4 PF15955.5 KIK34723.1 - 3.6 8.4 5.9 3.7e+02 1.9 0.0 5.9 9 0 0 9 9 8 0 Cuticle protein FLgD_tudor PF13861.6 KIK34723.1 - 4.7 7.5 12.1 4.3 7.6 0.1 5.7 7 0 0 7 7 7 0 FlgD Tudor-like domain Pkinase PF00069.25 KIK34726.1 - 2.4e-06 27.1 0.0 0.0088 15.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Zn_clus PF00172.18 KIK34727.1 - 8.2e-09 35.5 8.9 1.4e-08 34.8 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIK34727.1 - 1.9e-08 33.7 0.1 6.3e-08 32.0 0.0 1.7 1 1 0 2 2 2 1 Fungal specific transcription factor domain Totivirus_coat PF05518.11 KIK34727.1 - 0.15 10.1 0.0 3.8 5.4 0.0 2.0 2 0 0 2 2 2 0 Totivirus coat protein COQ9 PF08511.11 KIK34728.1 - 1.4e-07 31.1 0.0 2.5e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 COQ9 HEAT_2 PF13646.6 KIK34728.1 - 0.043 14.2 0.5 5.3 7.5 0.1 2.5 2 0 0 2 2 2 0 HEAT repeats SecG PF03840.14 KIK34731.1 - 0.26 11.4 4.2 1.3 9.2 4.2 2.2 1 1 0 1 1 1 0 Preprotein translocase SecG subunit OPT PF03169.15 KIK34732.1 - 6.3e-121 405.0 17.1 7.5e-121 404.7 17.1 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein GGACT PF06094.12 KIK34733.1 - 8e-19 68.4 0.0 1e-18 68.1 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF4136 PF13590.6 KIK34733.1 - 0.0073 16.9 0.0 0.0073 16.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4136) AIG2_2 PF13772.6 KIK34733.1 - 0.011 16.1 0.0 0.019 15.4 0.0 1.3 1 0 0 1 1 1 0 AIG2-like family zf-MYND PF01753.18 KIK34736.1 - 2.2e-08 34.1 15.4 3.9e-08 33.2 15.4 1.4 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.7 KIK34737.1 - 4.6e-11 42.4 0.1 1.4e-10 40.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK34737.1 - 9e-05 22.2 0.7 0.00076 19.3 0.1 2.6 2 0 0 2 2 2 1 F-box domain Asp_protease_2 PF13650.6 KIK34738.1 - 0.00017 22.2 0.0 0.00026 21.6 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK34738.1 - 0.00055 20.4 0.0 0.00082 19.9 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KIK34738.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Aspartyl protease BORCS6 PF10157.9 KIK34740.1 - 0.036 14.3 0.1 0.092 13.0 0.0 1.7 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 6 SRP1_TIP1 PF00660.17 KIK34740.1 - 0.045 13.8 0.0 0.43 10.7 0.0 2.2 2 0 0 2 2 2 0 Seripauperin and TIP1 family Pan3_PK PF18101.1 KIK34740.1 - 0.11 12.5 0.2 0.23 11.4 0.2 1.5 1 0 0 1 1 1 0 Pan3 Pseudokinase domain Pkinase_fungal PF17667.1 KIK34744.1 - 8.1e-47 159.9 0.0 5e-33 114.5 0.0 2.0 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 KIK34744.1 - 6.4e-06 26.3 1.4 6e-05 23.1 1.5 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIK34744.1 - 0.0001 21.8 0.2 0.00052 19.5 0.2 1.9 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIK34744.1 - 0.00015 21.4 0.1 0.00032 20.3 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KIK34744.1 - 0.15 11.4 0.2 0.35 10.2 0.2 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sfi1 PF08457.10 KIK34746.1 - 0.035 12.6 0.0 0.042 12.4 0.0 1.0 1 0 0 1 1 1 0 Sfi1 spindle body protein Mce4_CUP1 PF11887.8 KIK34746.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative KDZ PF18758.1 KIK34748.1 - 3.3e-48 164.2 0.0 5.2e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Peptidase_C48 PF02902.19 KIK34748.1 - 1.1e-11 44.9 0.1 2.5e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CxC1 PF18802.1 KIK34748.1 - 0.00012 22.2 0.1 0.00029 21.0 0.1 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases YjeF_N PF03853.15 KIK34750.1 - 4.2e-37 127.7 0.0 5.1e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus PALP PF00291.25 KIK34750.1 - 0.23 10.8 0.0 0.28 10.5 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme zf-MYND PF01753.18 KIK34751.1 - 2.8e-10 40.1 5.6 9.5e-10 38.4 5.6 2.0 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KIK34751.1 - 0.00016 21.7 3.5 0.00049 20.1 3.5 1.8 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Abhydrolase_6 PF12697.7 KIK34754.1 - 2.4e-16 61.0 1.0 3.7e-16 60.4 1.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cullin PF00888.22 KIK34755.1 - 3.6e-17 62.2 0.1 6.2e-17 61.5 0.1 1.3 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KIK34755.1 - 4.2e-17 62.4 0.0 1.7e-16 60.5 0.0 2.1 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 PI3K_1B_p101 PF10486.9 KIK34760.1 - 4.5 4.9 7.5 5.2 4.7 7.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit MARVEL PF01284.23 KIK34761.1 - 5.9e-06 26.4 13.6 8e-06 25.9 13.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain Silic_transp PF03842.13 KIK34761.1 - 0.0047 15.3 1.6 0.0089 14.4 1.6 1.4 1 0 0 1 1 1 1 Silicon transporter Pkinase PF00069.25 KIK34762.1 - 1.2e-60 205.1 0.0 9.2e-36 123.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK34762.1 - 9.5e-26 90.6 0.0 1e-14 54.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KIK34762.1 - 8.3e-05 23.2 7.3 8.3e-05 23.2 7.3 3.0 2 0 0 2 2 2 1 Protein kinase C terminal domain FTA2 PF13095.6 KIK34762.1 - 0.0017 18.0 0.0 0.21 11.2 0.1 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIK34762.1 - 0.0091 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK34762.1 - 0.015 15.3 0.3 4.8 7.0 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK34762.1 - 0.096 12.0 0.0 3.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Kinase-like RBM1CTR PF08081.11 KIK34763.1 - 0.037 14.1 1.1 0.086 12.9 1.1 1.6 1 1 0 1 1 1 0 RBM1CTR (NUC064) family DUF1494 PF07379.11 KIK34763.1 - 0.046 13.6 0.3 5.6 6.8 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1494) HTH_33 PF13592.6 KIK34766.1 - 0.00011 21.8 0.0 0.00011 21.8 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KIK34766.1 - 0.032 14.5 0.1 0.038 14.2 0.1 1.1 1 0 0 1 1 1 0 Transposase Helicase_C PF00271.31 KIK34768.1 - 6.5e-14 52.2 0.0 1.4e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KIK34768.1 - 3.3e-11 42.5 0.0 5.8e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ERCC3_RAD25_C PF16203.5 KIK34768.1 - 0.00017 20.9 0.0 0.00036 19.8 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Plavaka PF18759.1 KIK34770.1 - 3.5e-92 309.1 0.1 2.7e-50 171.4 0.0 2.3 1 1 1 2 2 2 2 Plavaka transposase DUF4188 PF13826.6 KIK34772.1 - 0.043 14.2 0.3 0.1 13.0 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4188) DUF35_N PF12172.8 KIK34773.1 - 2.7 8.0 8.5 0.33 10.9 3.0 2.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Amino_oxidase PF01593.24 KIK34778.1 - 2.5e-68 231.5 0.1 7.9e-68 229.8 0.1 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK34778.1 - 7.1e-11 42.2 0.2 2.2e-10 40.6 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KIK34778.1 - 0.00022 20.6 0.0 0.00033 20.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KIK34778.1 - 0.00023 20.5 0.6 0.022 14.0 0.2 2.4 2 1 2 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIK34778.1 - 0.00092 18.7 1.0 0.0014 18.1 0.6 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIK34778.1 - 0.00097 18.5 0.3 0.0018 17.6 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KIK34778.1 - 0.0018 17.6 0.4 0.0048 16.2 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK34778.1 - 0.0065 15.6 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIK34778.1 - 0.0098 15.5 2.3 0.014 15.0 0.8 1.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KIK34778.1 - 0.014 14.5 0.1 0.024 13.7 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KIK34778.1 - 0.038 14.5 3.6 0.061 13.9 0.1 2.5 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KIK34778.1 - 0.062 13.4 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pro_isomerase PF00160.21 KIK34779.1 - 4.2e-47 160.4 0.4 5e-47 160.1 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD F-box-like PF12937.7 KIK34780.1 - 0.00025 20.9 1.3 0.0018 18.1 0.1 2.5 2 0 0 2 2 2 1 F-box-like Cwf_Cwc_15 PF04889.12 KIK34780.1 - 1.2 8.8 4.5 1.8 8.2 4.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KIK34780.1 - 5 6.4 5.5 8 5.7 5.5 1.3 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 KIK34780.1 - 6.6 7.2 13.9 1.2 9.6 9.7 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain OPT PF03169.15 KIK34782.1 - 1.1e-194 648.6 69.8 1.3e-194 648.4 69.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein F-box-like PF12937.7 KIK34783.1 - 2.2e-07 30.6 2.2 3.3e-06 26.9 0.2 2.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK34783.1 - 9.9e-06 25.3 0.7 0.013 15.4 0.0 2.7 2 0 0 2 2 2 2 F-box domain LRR_8 PF13855.6 KIK34783.1 - 0.048 13.4 0.3 13 5.6 0.2 2.6 2 0 0 2 2 2 0 Leucine rich repeat Synaptobrevin PF00957.21 KIK34784.1 - 1.2e-34 117.9 2.6 1.4e-34 117.8 2.6 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF515 PF04415.12 KIK34784.1 - 0.91 7.8 5.5 1.1 7.6 5.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF515) zf-C2H2_12 PF18658.1 KIK34787.1 - 0.61 9.7 7.9 0.67 9.6 0.4 2.6 2 1 1 3 3 3 0 Zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 KIK34789.1 - 0.29 11.3 3.9 0.12 12.5 1.6 1.5 2 0 0 2 2 2 0 Aberrant zinc-finger Transpos_assoc PF13963.6 KIK34789.1 - 1.1 9.7 6.0 1.5 9.2 3.7 2.4 2 1 1 3 3 3 0 Transposase-associated domain zf-C2H2_12 PF18658.1 KIK34789.1 - 7.9 6.1 8.0 23 4.6 2.9 2.9 1 1 1 2 2 2 0 Zinc-finger C2H2-type Mo25 PF08569.11 KIK34790.1 - 3.7e-132 440.6 2.7 4.2e-132 440.5 2.7 1.0 1 0 0 1 1 1 1 Mo25-like Spore_GerQ PF09671.10 KIK34790.1 - 0.096 12.7 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Spore coat protein (Spore_GerQ) HTH_29 PF13551.6 KIK34791.1 - 9e-05 22.4 0.6 0.00018 21.5 0.1 1.7 2 0 0 2 2 2 1 Winged helix-turn helix LRR_9 PF14580.6 KIK34793.1 - 0.042 13.3 0.1 0.7 9.4 0.0 2.2 2 0 0 2 2 2 0 Leucine-rich repeat LRR_4 PF12799.7 KIK34793.1 - 2.1 8.9 5.6 32 5.1 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) DER1 PF04511.15 KIK34794.1 - 2.9e-31 108.9 0.6 3.4e-31 108.7 0.6 1.0 1 0 0 1 1 1 1 Der1-like family Ion_trans_2 PF07885.16 KIK34795.1 - 4e-31 106.8 32.7 2.7e-17 62.5 8.8 3.3 3 0 0 3 3 3 2 Ion channel FAM75 PF14650.6 KIK34795.1 - 0.041 13.4 1.8 0.071 12.6 1.8 1.3 1 0 0 1 1 1 0 FAM75 family Transp_cyt_pur PF02133.15 KIK34796.1 - 2.2e-24 86.1 42.5 4.6e-24 85.0 42.5 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.15 KIK34797.1 - 3.5e-32 111.7 20.1 6e-32 111.0 20.1 1.3 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TM_helix PF05552.12 KIK34797.1 - 4.6 7.3 7.7 1.2 9.2 1.4 2.9 2 1 1 3 3 3 0 Conserved TM helix TolB_N PF04052.13 KIK34799.1 - 0.054 13.7 0.0 0.062 13.5 0.0 1.1 1 0 0 1 1 1 0 TolB amino-terminal domain Cytadhesin_P30 PF07271.11 KIK34800.1 - 1.4 8.4 3.4 2.4 7.7 3.4 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 DUF4186 PF13811.6 KIK34801.1 - 2.9 8.0 6.3 2.4 8.2 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4186) Phage_integrase PF00589.22 KIK34802.1 - 0.047 13.5 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 Phage integrase family TPR_1 PF00515.28 KIK34804.1 - 3.6e-07 29.7 0.0 0.62 10.0 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK34804.1 - 1.5e-06 27.9 4.0 0.21 11.8 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat UBA PF00627.31 KIK34804.1 - 2.5e-05 24.1 0.7 0.00033 20.5 0.0 2.6 3 0 0 3 3 3 1 UBA/TS-N domain DnaJ PF00226.31 KIK34804.1 - 0.0077 16.3 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_16 PF13432.6 KIK34804.1 - 0.065 13.9 0.2 0.065 13.9 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat F-box-like PF12937.7 KIK34805.1 - 1.3e-07 31.4 0.3 9.4e-07 28.6 0.0 2.5 2 1 0 2 2 2 1 F-box-like VPS28 PF03997.12 KIK34809.1 - 2.5e-70 236.0 0.0 2.9e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein zf-MYND PF01753.18 KIK34810.1 - 4.7e-09 36.2 12.9 8.1e-09 35.4 12.9 1.4 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KIK34811.1 - 7.9e-09 35.5 13.8 1.4e-08 34.7 13.8 1.4 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.7 KIK34812.1 - 0.00063 19.6 0.2 0.00063 19.6 0.2 2.6 2 1 0 2 2 2 1 F-box-like APG17 PF04108.12 KIK34812.1 - 0.0093 15.1 0.1 0.014 14.5 0.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 Phage_GP20 PF06810.11 KIK34812.1 - 0.033 14.0 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Saccharop_dh_N PF04455.12 KIK34812.1 - 0.1 13.0 1.7 0.2 12.1 1.7 1.4 1 0 0 1 1 1 0 LOR/SDH bifunctional enzyme conserved region MitMem_reg PF13012.6 KIK34812.1 - 0.26 11.7 2.8 0.27 11.7 0.6 2.1 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function F-box-like PF12937.7 KIK34813.1 - 4.3e-09 36.1 3.9 7.6e-09 35.3 2.2 2.4 2 0 0 2 2 2 1 F-box-like WD40 PF00400.32 KIK34814.1 - 4.2e-09 36.9 0.1 1.3e-08 35.3 0.0 1.7 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34814.1 - 8e-05 22.9 0.0 8.7e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK34814.1 - 0.016 14.2 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KIK34815.1 - 2.3e-06 28.2 0.1 0.0081 17.0 0.0 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat P3A PF08727.11 KIK34815.1 - 0.13 11.6 0.6 0.22 10.9 0.5 1.5 1 1 0 1 1 1 0 Poliovirus 3A protein like CNH PF00780.22 KIK34817.1 - 1.5e-78 264.2 0.0 3.9e-78 262.8 0.0 1.6 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 KIK34817.1 - 2.7e-41 140.8 0.0 5e-41 140.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KIK34817.1 - 4.9e-35 121.4 0.0 7.7e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KIK34817.1 - 9.1e-14 51.3 0.1 2e-13 50.2 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 KIK34817.1 - 0.0094 15.8 0.8 0.12 12.2 0.1 2.8 3 1 0 3 3 3 1 Pleckstrin homology domain Polysacc_deac_1 PF01522.21 KIK34818.1 - 3.2e-26 91.7 0.0 5.2e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase ATP-grasp_4 PF13535.6 KIK34818.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain Orthopox_A5L PF06193.11 KIK34818.1 - 0.86 9.0 9.9 0.37 10.2 7.1 1.7 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like Sec1 PF00995.23 KIK34819.1 - 4.2e-130 435.7 0.0 4.9e-130 435.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family AAA PF00004.29 KIK34820.1 - 3.7e-42 143.9 0.0 6.5e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KIK34820.1 - 6.6e-12 45.2 0.3 2.2e-11 43.5 0.0 2.1 3 0 0 3 3 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KIK34820.1 - 2.4e-11 43.3 0.1 5e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KIK34820.1 - 1.9e-07 31.7 0.2 0.00017 22.0 0.1 3.0 2 1 2 4 4 3 1 AAA ATPase domain AAA_5 PF07728.14 KIK34820.1 - 2.2e-07 31.0 0.5 3.1e-06 27.2 0.1 2.8 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIK34820.1 - 7.5e-06 26.2 0.0 3.8e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KIK34820.1 - 1.1e-05 25.2 0.0 2.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KIK34820.1 - 0.00013 22.3 0.1 0.0044 17.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain Prot_ATP_OB_N PF17758.1 KIK34820.1 - 0.0015 18.1 0.1 0.0063 16.1 0.0 2.0 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain DUF815 PF05673.13 KIK34820.1 - 0.002 17.3 0.0 0.0034 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 KIK34820.1 - 0.0027 17.1 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KIK34820.1 - 0.0035 17.9 0.0 0.011 16.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KIK34820.1 - 0.0039 16.7 0.0 0.0078 15.7 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KIK34820.1 - 0.0042 17.4 0.0 0.0085 16.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase TsaE PF02367.17 KIK34820.1 - 0.0049 16.9 0.0 0.0089 16.0 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 KIK34820.1 - 0.0057 15.9 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KIK34820.1 - 0.006 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KIK34820.1 - 0.0063 16.7 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KIK34820.1 - 0.0085 16.1 0.0 0.041 13.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KIK34820.1 - 0.016 14.9 0.0 0.051 13.3 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 KIK34820.1 - 0.018 14.5 0.1 0.035 13.6 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_3 PF07726.11 KIK34820.1 - 0.019 14.8 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KIK34820.1 - 0.021 14.5 0.1 0.055 13.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 KIK34820.1 - 0.023 14.4 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIK34820.1 - 0.028 14.7 0.0 0.059 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KIK34820.1 - 0.044 13.7 0.1 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 KIK34820.1 - 0.05 13.2 0.2 0.14 11.7 0.1 1.7 2 0 0 2 2 1 0 AAA domain ATPase PF06745.13 KIK34820.1 - 0.062 12.6 0.7 0.18 11.2 0.0 2.0 3 0 0 3 3 3 0 KaiC Parvo_NS1 PF01057.17 KIK34820.1 - 0.063 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 KIK34820.1 - 0.095 12.0 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 KIK34820.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KIK34820.1 - 0.12 12.1 0.8 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KIK34820.1 - 0.47 10.9 2.0 12 6.3 0.0 2.4 3 0 0 3 3 2 0 AAA domain PSY3 PF16836.5 KIK34821.1 - 0.15 11.6 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description DUF3648 PF12364.8 KIK34824.1 - 0.085 13.1 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) DUF5498 PF17602.2 KIK34825.1 - 0.0016 18.9 0.1 0.0022 18.5 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5498) Pkinase_Tyr PF07714.17 KIK34830.1 - 1.8e-50 171.7 0.0 3.3e-50 170.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK34830.1 - 5.7e-38 130.8 0.0 1.1e-37 129.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK34830.1 - 0.0029 17.0 0.1 0.0059 16.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FtsK_gamma PF09397.10 KIK34836.1 - 0.083 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Ftsk gamma domain polyprenyl_synt PF00348.17 KIK34838.1 - 9.9e-58 195.2 0.0 2.8e-29 102.0 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase Efg1 PF10153.9 KIK34839.1 - 2.5e-37 127.7 11.6 5.6e-37 126.6 11.6 1.6 1 0 0 1 1 1 1 rRNA-processing protein Efg1 DUF3509 PF12021.8 KIK34839.1 - 7.4 6.4 6.8 0.52 10.1 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3509) IKI3 PF04762.12 KIK34840.1 - 1.4e-232 774.6 0.0 2.3e-178 595.2 0.0 2.1 1 1 1 2 2 2 2 IKI3 family ANAPC4_WD40 PF12894.7 KIK34840.1 - 5.8e-07 29.7 0.8 0.57 10.5 0.0 5.6 4 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 KIK34840.1 - 0.21 11.5 0.4 5.4 6.9 0.0 2.9 1 1 0 2 2 2 0 Region in Clathrin and VPS CD225 PF04505.12 KIK34842.1 - 0.026 14.6 2.7 0.073 13.2 2.7 1.8 1 0 0 1 1 1 0 Interferon-induced transmembrane protein UPF0182 PF03699.13 KIK34842.1 - 0.44 8.6 3.1 0.37 8.9 2.0 1.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) SlyX PF04102.12 KIK34846.1 - 3 8.5 12.0 1.7 9.4 0.3 3.7 3 0 0 3 3 3 0 SlyX Pex26 PF07163.12 KIK34846.1 - 4.2 6.6 5.8 1.2 8.4 1.1 2.2 2 0 0 2 2 2 0 Pex26 protein DivIC PF04977.15 KIK34846.1 - 9.8 6.0 19.8 0.42 10.4 2.8 3.8 3 0 0 3 3 3 0 Septum formation initiator HNF-1A_C PF04813.12 KIK34847.1 - 0.033 14.9 0.2 0.035 14.9 0.2 1.0 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus DUF2575 PF10837.8 KIK34847.1 - 0.11 12.9 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) RhoGEF PF00621.20 KIK34849.1 - 1.1e-12 48.6 0.0 1.4e-12 48.3 0.0 1.0 1 0 0 1 1 1 1 RhoGEF domain DUF2316 PF10078.9 KIK34849.1 - 0.14 12.4 0.0 21 5.4 0.0 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) VWA PF00092.28 KIK34852.1 - 2.6e-09 37.5 0.0 4.2e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIK34852.1 - 6.8e-08 33.1 0.0 1.6e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Integrin_beta PF00362.18 KIK34852.1 - 0.013 15.2 0.0 0.14 11.8 0.0 2.2 1 1 1 2 2 2 0 Integrin beta chain VWA domain MTBP_mid PF14919.6 KIK34852.1 - 0.062 12.5 0.3 0.086 12.0 0.3 1.1 1 0 0 1 1 1 0 MDM2-binding Utp21 PF04192.12 KIK34856.1 - 0.047 13.2 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Plavaka PF18759.1 KIK34857.1 - 7.1e-29 101.1 0.0 2.6e-28 99.2 0.0 1.8 1 1 0 1 1 1 1 Plavaka transposase IL7 PF01415.16 KIK34857.1 - 0.044 13.8 0.5 0.085 12.9 0.5 1.4 1 0 0 1 1 1 0 Interleukin 7/9 family O-FucT PF10250.9 KIK34862.1 - 1.2e-11 45.0 0.0 1.5e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase WD40 PF00400.32 KIK34863.1 - 5.4e-37 125.2 11.9 1.1e-05 26.1 0.5 8.1 6 1 1 7 7 7 7 WD domain, G-beta repeat HET PF06985.11 KIK34863.1 - 1.6e-09 38.3 3.0 2.8e-07 31.0 0.2 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ANAPC4_WD40 PF12894.7 KIK34863.1 - 6.4e-08 32.8 0.1 0.85 10.0 0.0 5.8 1 1 6 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK34863.1 - 2.7e-06 27.4 0.0 0.86 9.4 0.0 3.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A TPR_2 PF07719.17 KIK34863.1 - 0.00017 21.5 11.8 0.59 10.4 0.1 7.0 8 0 0 8 8 7 1 Tetratricopeptide repeat Ge1_WD40 PF16529.5 KIK34863.1 - 0.00034 19.7 0.0 0.52 9.2 0.0 2.7 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_1 PF00515.28 KIK34863.1 - 0.00035 20.3 6.4 0.51 10.2 0.1 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK34863.1 - 0.015 15.3 3.7 7.2 6.9 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK34863.1 - 0.02 14.6 1.6 0.46 10.2 0.1 3.3 3 0 0 3 3 3 0 TPR repeat TPR_19 PF14559.6 KIK34863.1 - 0.17 12.4 15.5 2.4 8.7 0.6 4.2 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 KIK34863.1 - 0.41 10.7 3.0 8.7 6.5 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK34863.1 - 0.48 11.4 9.9 19 6.4 0.1 4.9 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK34863.1 - 0.51 11.0 12.7 0.42 11.3 0.6 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat UL11 PF11094.8 KIK34865.1 - 0.083 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Membrane-associated tegument protein zf-H2C2_5 PF13909.6 KIK34867.1 - 5.7e-13 48.4 8.9 8.7e-05 22.2 0.3 3.3 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIK34867.1 - 3.2e-10 39.9 14.5 0.0037 17.6 0.7 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK34867.1 - 4.6e-08 33.1 14.6 5.4e-05 23.4 0.4 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK34867.1 - 1.2e-06 28.8 13.5 0.11 13.5 0.8 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger OrsD PF12013.8 KIK34867.1 - 0.0092 16.4 8.6 2.2 8.7 0.2 3.0 1 1 2 3 3 3 2 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_jaz PF12171.8 KIK34867.1 - 0.021 15.1 5.0 0.91 9.9 0.0 3.6 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 KIK34867.1 - 0.048 14.3 7.5 2.3 9.0 2.3 2.6 1 1 1 2 2 2 0 TRAF-type zinc finger DUF1390 PF07150.11 KIK34867.1 - 0.1 12.3 1.3 7 6.3 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1390) zf-BED PF02892.15 KIK34867.1 - 2.4 8.2 8.3 3.6 7.7 1.1 2.5 1 1 1 2 2 2 0 BED zinc finger WD40 PF00400.32 KIK34868.1 - 1.7e-19 69.8 6.5 4.8e-08 33.5 0.7 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.8 KIK34868.1 - 4.5e-05 22.3 0.1 0.23 10.1 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KIK34868.1 - 9.7e-05 22.6 0.1 0.12 12.7 0.0 3.5 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Abhydrolase_1 PF00561.20 KIK34869.1 - 2.5e-20 73.2 1.0 8.6e-18 64.9 1.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK34869.1 - 4e-17 63.5 0.3 4e-17 63.5 0.3 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK34869.1 - 1e-16 61.0 0.1 1.6e-16 60.3 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KIK34869.1 - 6.1e-08 32.7 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 KIK34869.1 - 7e-05 22.4 0.7 0.0044 16.5 0.1 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 KIK34869.1 - 0.0017 18.0 0.8 0.12 11.9 0.4 2.8 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KIK34869.1 - 0.0026 17.6 0.3 0.75 9.6 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 KIK34869.1 - 0.0044 16.8 0.6 3.3 7.4 0.0 2.6 2 1 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S28 PF05577.12 KIK34869.1 - 0.023 13.5 0.7 0.051 12.4 0.1 1.7 2 0 0 2 2 2 0 Serine carboxypeptidase S28 UPF0227 PF05728.12 KIK34869.1 - 0.065 13.2 0.0 12 5.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) POM121 PF15229.6 KIK34871.1 - 0.017 14.8 7.9 0.022 14.4 7.9 1.0 1 0 0 1 1 1 0 POM121 family GET2 PF08690.10 KIK34871.1 - 0.31 10.7 2.5 0.35 10.5 2.5 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Myb_DNA-binding PF00249.31 KIK34872.1 - 7e-13 48.5 0.6 1.1e-12 48.0 0.6 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK34872.1 - 2.3e-11 43.7 0.1 3.9e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KIK34872.1 - 0.0033 17.3 0.1 0.0051 16.7 0.1 1.2 1 0 0 1 1 1 1 Myb DNA-binding like MASE1 PF05231.14 KIK34873.1 - 3.3e-05 23.2 3.9 4.8e-05 22.7 3.9 1.1 1 0 0 1 1 1 1 MASE1 DUF4131 PF13567.6 KIK34873.1 - 0.019 14.6 0.5 0.42 10.2 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) SUR7 PF06687.12 KIK34873.1 - 0.023 14.3 2.3 0.043 13.4 2.3 1.4 1 0 0 1 1 1 0 SUR7/PalI family DUF2973 PF11189.8 KIK34873.1 - 0.031 14.4 0.3 6.1 7.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) Myelin_PLP PF01275.19 KIK34873.1 - 0.12 12.2 2.7 9.2 6.1 0.9 2.3 2 0 0 2 2 2 0 Myelin proteolipid protein (PLP or lipophilin) PEN-2 PF10251.9 KIK34873.1 - 1 9.9 4.3 0.41 11.1 1.0 2.0 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase DUF2188 PF09954.9 KIK34875.1 - 0.39 10.9 9.5 2.7 8.2 0.1 4.0 2 1 3 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2188) Hyr1 PF15789.5 KIK34876.1 - 0.27 10.8 4.0 1.5 8.4 0.2 2.6 2 1 1 3 3 3 0 Hyphally regulated cell wall GPI-anchored protein 1 RTC4 PF14474.6 KIK34877.1 - 5.2e-08 33.1 0.0 9.6e-08 32.2 0.0 1.5 2 0 0 2 2 2 1 RTC4-like domain RNase_HII PF01351.18 KIK34879.1 - 5.4e-46 156.9 0.0 2.1e-44 151.7 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease HII IFR3_antag PF14754.6 KIK34879.1 - 0.1 11.8 0.0 0.24 10.6 0.0 1.5 2 0 0 2 2 2 0 Papain-like auto-proteinase DUF3759 PF12585.8 KIK34880.1 - 2.9e-32 110.5 12.0 3.5e-32 110.3 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) COesterase PF00135.28 KIK34881.1 - 1e-82 278.7 2.3 1.8e-81 274.5 2.3 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK34881.1 - 1.5e-12 47.8 0.1 5.9e-10 39.4 0.1 2.9 2 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK34881.1 - 3.4e-05 23.4 0.0 6.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KIK34881.1 - 0.0093 15.6 0.5 0.03 14.0 0.5 1.7 1 1 0 1 1 1 1 Putative esterase Acetyltransf_3 PF13302.7 KIK34883.1 - 1.1e-13 52.0 0.0 1.6e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK34883.1 - 1.7e-05 25.0 0.0 9.4e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 KIK34884.1 - 0.008 16.2 3.5 0.008 16.2 3.5 5.1 3 1 2 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 KIK34884.1 - 0.014 15.5 22.3 0.014 15.5 22.3 5.4 4 1 1 5 5 5 0 TPR/MLP1/MLP2-like protein UFD1 PF03152.14 KIK34884.1 - 0.1 12.1 0.1 0.27 10.7 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 DASH_Dad4 PF08650.10 KIK34884.1 - 0.18 11.8 2.4 0.45 10.5 0.2 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad4 Fic_N PF13784.6 KIK34884.1 - 1.1 9.3 5.8 0.21 11.6 0.5 2.7 2 1 0 2 2 2 0 Fic/DOC family N-terminal Glyco_hydro_38C PF07748.13 KIK34885.1 - 3.8e-25 89.2 0.0 6e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro38C2 PF17677.1 KIK34885.1 - 2.1e-08 34.1 0.0 4.3e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Abhydrolase_2 PF02230.16 KIK34888.1 - 1.2e-10 41.6 0.0 2e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KIK34888.1 - 0.00013 22.6 1.1 0.00018 22.2 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4399 PF14347.6 KIK34889.1 - 0.0051 17.2 0.1 0.016 15.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4399) HET PF06985.11 KIK34890.1 - 2.1e-11 44.4 2.5 2e-08 34.7 0.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) CRC_subunit PF08624.10 KIK34891.1 - 2.5e-43 147.8 0.0 3.9e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Lactococcin_972 PF09683.10 KIK34891.1 - 0.049 14.2 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 Bacteriocin (Lactococcin_972) DUF982 PF06169.12 KIK34895.1 - 0.0072 16.3 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF982) ABC_tran PF00005.27 KIK34896.1 - 1.1e-24 87.5 0.0 2e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KIK34896.1 - 4.9e-12 45.6 26.4 6.6e-12 45.2 26.4 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 KIK34896.1 - 3.6e-08 33.6 0.1 3.4e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 KIK34896.1 - 0.0044 16.5 20.3 0.0044 16.5 20.3 2.2 2 1 0 2 2 2 1 ABC-2 type transporter SMC_N PF02463.19 KIK34896.1 - 0.0078 15.7 0.2 1.1 8.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIK34896.1 - 0.017 15.6 0.0 0.028 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF4162 PF13732.6 KIK34896.1 - 0.037 14.8 0.0 0.075 13.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) Thioredoxin PF00085.20 KIK34899.1 - 1e-16 60.8 0.0 1.3e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KIK34899.1 - 7.2e-06 25.9 0.0 8.6e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 KIK34899.1 - 7.3e-05 23.2 0.0 0.00015 22.2 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KIK34899.1 - 0.00079 19.6 0.1 0.0012 18.9 0.1 1.3 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KIK34899.1 - 0.0011 18.6 0.0 0.0013 18.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 KIK34899.1 - 0.025 14.9 0.1 0.056 13.8 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like CBM27 PF09212.10 KIK34899.1 - 0.043 14.0 0.0 0.047 13.9 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding module 27 HEPN_DZIP3 PF18738.1 KIK34899.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 DZIP3/ hRUL138-like HEPN VASt PF16016.5 KIK34900.1 - 2e-38 132.2 0.1 3.6e-38 131.4 0.1 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KIK34900.1 - 6.9e-23 80.7 0.0 1.2e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 GRAM domain DLH PF01738.18 KIK34901.1 - 5.1e-26 91.6 0.0 5.8e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Myb_DNA-bind_4 PF13837.6 KIK34902.1 - 4.5e-05 23.7 0.0 7.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain KDZ PF18758.1 KIK34903.1 - 1.4e-44 152.4 2.0 3e-43 148.0 0.6 2.9 2 1 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK34903.1 - 2.5e-14 53.3 1.8 6.1e-14 52.1 1.8 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CNP_C_terminal PF17839.1 KIK34905.1 - 0.17 12.6 3.0 0.27 12.0 0.8 2.2 2 0 0 2 2 2 0 C-terminal domain of cyclic nucleotide phosphodiesterase Transposase_21 PF02992.14 KIK34907.1 - 9e-08 31.6 0.2 1.5e-07 30.8 0.2 1.4 1 0 0 1 1 1 1 Transposase family tnp2 Lactamase_B_3 PF13483.6 KIK34909.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.5 2 0 0 2 2 2 0 Beta-lactamase superfamily domain TPR_MLP1_2 PF07926.12 KIK34911.1 - 0.027 14.5 1.1 0.037 14.1 1.1 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Pet20 PF08692.10 KIK34912.1 - 0.073 13.8 0.5 0.76 10.5 0.0 2.6 2 1 1 3 3 3 0 Mitochondrial protein Pet20 FAD_binding_3 PF01494.19 KIK34914.1 - 0.00014 21.2 0.0 0.00016 21.0 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KIK34914.1 - 0.043 13.1 0.0 0.055 12.7 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK34914.1 - 0.059 12.4 0.0 0.069 12.2 0.0 1.0 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 KIK34914.1 - 0.093 13.0 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK34914.1 - 0.1 11.8 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK34914.1 - 0.12 11.1 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein DUF983 PF06170.12 KIK34915.1 - 0.028 14.8 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF983) CHAT PF12770.7 KIK34916.1 - 7.1e-35 120.8 0.0 1.9e-34 119.4 0.0 1.7 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK34916.1 - 1.1e-15 57.0 13.1 0.023 14.6 0.0 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 KIK34916.1 - 2.6e-09 36.4 1.6 0.95 9.6 0.0 8.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK34916.1 - 1.3e-08 35.0 13.1 2.2 8.6 0.0 8.3 7 2 1 8 8 8 2 Tetratricopeptide repeat Sel1 PF08238.12 KIK34916.1 - 2.2e-06 28.2 0.2 3.2 8.6 0.0 6.3 7 0 0 7 7 6 1 Sel1 repeat TPR_1 PF00515.28 KIK34916.1 - 4.1e-06 26.4 11.8 6.4 6.8 0.0 8.9 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK34916.1 - 1.9e-05 25.2 7.2 8.8 7.1 0.0 6.6 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK34916.1 - 0.00048 19.8 0.0 5.8 6.7 0.0 6.0 7 0 0 7 7 7 1 TPR repeat YkuI_C PF10388.9 KIK34916.1 - 0.0011 18.7 0.3 8.1 6.2 0.0 5.2 6 1 1 7 7 7 1 EAL-domain associated signalling protein domain Surp PF01805.20 KIK34916.1 - 0.019 14.9 0.0 0.057 13.4 0.0 1.8 2 0 0 2 2 2 0 Surp module TPR_14 PF13428.6 KIK34916.1 - 0.031 15.1 15.4 11 7.2 0.0 8.6 8 1 2 10 10 10 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK34916.1 - 0.61 10.3 12.5 29 5.1 0.0 7.4 9 0 0 9 9 9 0 Tetratricopeptide repeat PKHD_C PF18331.1 KIK34916.1 - 1.6 8.9 10.0 57 3.9 0.1 6.3 7 1 1 8 8 8 0 PKHD-type hydroxylase C-terminal domain DCB PF16213.5 KIK34917.1 - 6.5e-55 185.5 4.6 1.6e-54 184.3 3.8 2.2 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KIK34917.1 - 6.1e-52 175.7 9.5 1e-51 175.0 3.2 3.5 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 KIK34917.1 - 3.7e-37 127.9 3.6 3.2e-20 71.9 1.0 3.7 3 1 0 3 3 3 3 C-terminal region of Mon2 protein DUF1981 PF09324.10 KIK34917.1 - 0.00015 21.6 0.5 0.0033 17.2 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) RTP1_C1 PF10363.9 KIK34917.1 - 0.045 13.9 0.1 1.3 9.2 0.0 3.4 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 TAF6_C PF07571.13 KIK34917.1 - 0.82 10.0 2.4 23 5.4 0.0 3.8 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Ank_2 PF12796.7 KIK34918.1 - 6.6e-10 39.4 0.2 2.2e-08 34.5 0.2 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIK34918.1 - 1.1e-08 35.2 0.8 7.2e-07 29.4 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KIK34918.1 - 3.4e-08 33.9 0.6 0.00073 20.1 0.0 3.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK34918.1 - 1.4e-05 25.1 0.1 0.0034 17.8 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KIK34918.1 - 2e-05 24.8 1.0 0.00039 20.7 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeat ERCC4 PF02732.15 KIK34919.1 - 2.7e-06 27.7 0.0 0.00025 21.3 0.0 2.4 1 1 0 1 1 1 1 ERCC4 domain REV1_C PF16727.5 KIK34920.1 - 0.18 12.2 0.1 5.2 7.5 0.0 2.4 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain Cauli_VI PF01693.16 KIK34922.1 - 0.00066 19.9 1.1 0.0014 18.9 1.1 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin SNN_linker PF09050.10 KIK34922.1 - 4.6 7.1 4.4 7.4 6.4 4.4 1.3 1 0 0 1 1 1 0 Stannin unstructured linker CxC2 PF18803.1 KIK34924.1 - 2.4e-43 146.7 0.0 2.4e-43 146.7 0.0 2.9 3 0 0 3 3 3 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIK34924.1 - 7e-32 110.8 0.0 1.5e-31 109.8 0.0 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK34924.1 - 4.5e-05 23.5 0.0 0.00015 21.9 0.0 1.9 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK34924.1 - 0.0012 18.7 0.2 0.0097 15.7 0.0 2.7 3 0 0 3 3 3 1 CxC3 like cysteine cluster associated with KDZ transposases F-box-like PF12937.7 KIK34925.1 - 0.056 13.3 0.4 0.098 12.6 0.4 1.4 1 1 0 1 1 1 0 F-box-like WD40 PF00400.32 KIK34926.1 - 1.3e-139 449.9 49.4 1.2e-09 38.6 0.0 15.1 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34926.1 - 3.8e-39 132.9 0.1 0.0098 16.2 0.0 13.7 1 1 11 13 13 13 10 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK34926.1 - 6.6e-35 120.6 9.1 0.017 14.1 0.0 13.7 3 2 11 14 14 14 13 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK34926.1 - 8.3e-15 54.3 19.8 4.1 7.5 0.1 12.6 12 0 0 12 12 12 5 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KIK34926.1 - 2.5e-13 50.3 0.0 0.012 15.5 0.0 5.7 2 1 6 8 8 8 5 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK34926.1 - 9.4e-10 37.7 36.7 0.6 8.7 0.1 12.5 5 3 8 14 14 14 6 Nucleoporin Nup120/160 AAA_16 PF13191.6 KIK34926.1 - 2.1e-06 28.2 0.0 7.5e-06 26.4 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain NACHT PF05729.12 KIK34926.1 - 2.5e-06 27.5 0.0 4.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain WD40_like PF17005.5 KIK34926.1 - 0.00047 19.6 0.0 21 4.3 0.0 6.6 8 2 1 9 9 9 0 WD40-like domain Nbas_N PF15492.6 KIK34926.1 - 0.012 14.9 13.3 21 4.3 0.0 8.8 12 0 0 12 12 12 0 Neuroblastoma-amplified sequence, N terminal Glyoxal_oxid_N PF07250.11 KIK34926.1 - 1.7 7.8 4.7 4.2 6.5 0.0 3.9 4 1 1 5 5 5 0 Glyoxal oxidase N-terminus LPP PF04728.13 KIK34928.1 - 0.012 15.9 2.1 1.7 9.1 0.2 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper PAP2 PF01569.21 KIK34928.1 - 0.062 13.1 0.6 0.077 12.8 0.6 1.2 1 0 0 1 1 1 0 PAP2 superfamily IFT46_B_C PF12317.8 KIK34928.1 - 0.075 12.8 0.0 0.087 12.6 0.0 1.1 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal DUF948 PF06103.11 KIK34928.1 - 2 8.7 8.0 0.29 11.4 1.9 2.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DAGK_prokar PF01219.19 KIK34928.1 - 2.6 7.9 8.3 0.21 11.5 1.0 2.3 1 1 1 2 2 2 0 Prokaryotic diacylglycerol kinase AA_permease_2 PF13520.6 KIK34929.1 - 1e-75 255.2 39.2 1.3e-75 254.9 39.2 1.1 1 0 0 1 1 1 1 Amino acid permease HTH_Tnp_Tc5 PF03221.16 KIK34930.1 - 2.1e-06 27.7 0.1 2.4e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 KIK34931.1 - 2.6e-05 24.0 0.0 2.8e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 KIK34932.1 - 8.5e-12 45.1 0.0 1.1e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease SAP PF02037.27 KIK34933.1 - 1.6e-07 30.9 0.1 3.1e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 SAP domain Miff PF05644.11 KIK34933.1 - 0.016 14.8 1.4 0.021 14.5 1.4 1.1 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff DDRGK PF09756.9 KIK34933.1 - 0.029 14.0 10.4 0.04 13.5 10.4 1.2 1 0 0 1 1 1 0 DDRGK domain Peptidase_S49_N PF08496.10 KIK34933.1 - 2.2 8.3 8.6 4.2 7.4 8.6 1.4 1 1 0 1 1 1 0 Peptidase family S49 N-terminal Asp PF00026.23 KIK34936.1 - 0.0028 17.1 0.1 0.0033 16.9 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease eIF3_subunit PF08597.10 KIK34937.1 - 0.011 15.7 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit AAA_12 PF13087.6 KIK34938.1 - 3.1e-10 40.0 0.0 3.7e-10 39.8 0.0 1.0 1 0 0 1 1 1 1 AAA domain Dna2 PF08696.11 KIK34939.1 - 1.1e-32 113.5 0.1 2e-31 109.4 0.1 2.1 1 1 0 1 1 1 1 DNA replication factor Dna2 Aminotran_3 PF00202.21 KIK34939.1 - 0.13 10.9 0.0 0.24 10.0 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-III DUF3446 PF11928.8 KIK34941.1 - 0.016 15.5 1.4 0.018 15.3 1.4 1.1 1 0 0 1 1 1 0 Early growth response N-terminal domain F-box PF00646.33 KIK34943.1 - 0.0012 18.7 0.5 0.0028 17.5 0.5 1.7 2 0 0 2 2 2 1 F-box domain FlxA PF14282.6 KIK34944.1 - 0.00078 19.4 0.8 0.0012 18.8 0.8 1.3 1 0 0 1 1 1 1 FlxA-like protein UPF0242 PF06785.11 KIK34944.1 - 0.0036 17.4 1.4 0.0052 16.9 1.4 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Golgin_A5 PF09787.9 KIK34944.1 - 0.02 14.4 4.3 0.025 14.0 4.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 SpecificRecomb PF10136.9 KIK34944.1 - 0.021 13.2 0.2 0.025 12.9 0.2 1.0 1 0 0 1 1 1 0 Site-specific recombinase Spc7 PF08317.11 KIK34944.1 - 0.054 12.4 4.1 0.079 11.8 4.1 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4574 PF15141.6 KIK34944.1 - 0.13 12.2 1.3 0.24 11.3 1.3 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Phage_Mu_Gam PF07352.12 KIK34944.1 - 0.13 12.1 4.9 0.14 12.1 2.5 1.9 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein zf-RING_UBOX PF13445.6 KIK34945.1 - 3.3e-05 23.8 5.8 3.3e-05 23.8 5.8 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIK34945.1 - 0.00024 20.9 11.3 0.013 15.4 4.4 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK34945.1 - 0.00057 20.2 6.3 0.00057 20.2 6.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK34945.1 - 0.0016 18.2 6.3 0.0016 18.2 6.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK34945.1 - 0.0025 17.6 5.2 0.0025 17.6 5.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF3584 PF12128.8 KIK34945.1 - 0.0032 15.1 5.7 0.0042 14.7 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) CIAPIN1 PF05093.13 KIK34945.1 - 0.0068 16.9 1.8 0.0073 16.8 0.3 1.8 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis zf-C3HC4_4 PF15227.6 KIK34945.1 - 0.0072 16.5 5.1 0.0072 16.5 5.1 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KIK34945.1 - 0.0093 15.8 1.8 0.023 14.6 1.8 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein ATG16 PF08614.11 KIK34945.1 - 0.044 14.0 8.0 0.07 13.4 8.0 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) GP41 PF00517.17 KIK34945.1 - 0.051 13.5 0.4 0.081 12.8 0.4 1.2 1 0 0 1 1 1 0 Retroviral envelope protein Uso1_p115_C PF04871.13 KIK34945.1 - 0.053 13.9 8.7 0.085 13.2 8.7 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region SWIRM-assoc_1 PF16495.5 KIK34945.1 - 0.056 13.4 4.8 0.12 12.3 4.8 1.6 1 0 0 1 1 1 0 SWIRM-associated region 1 HAUS5 PF14817.6 KIK34945.1 - 0.057 12.2 6.0 0.074 11.8 6.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 zf-RING_5 PF14634.6 KIK34945.1 - 0.066 13.2 14.2 0.051 13.5 6.0 2.4 2 0 0 2 2 2 0 zinc-RING finger domain NAP PF00956.18 KIK34945.1 - 0.073 12.2 0.2 0.094 11.9 0.2 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Exonuc_VII_L PF02601.15 KIK34945.1 - 0.1 12.2 2.5 0.13 11.8 2.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prok-RING_4 PF14447.6 KIK34945.1 - 0.29 11.0 12.7 1.8 8.5 6.1 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KIK34945.1 - 0.31 11.2 9.0 0.057 13.6 4.3 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 Spc7 PF08317.11 KIK34945.1 - 0.47 9.3 8.3 0.67 8.8 8.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-CpG_bind_C PF12269.8 KIK34945.1 - 0.55 10.0 7.1 0.11 12.3 3.5 1.6 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain UPF0242 PF06785.11 KIK34945.1 - 0.61 10.2 6.6 0.87 9.7 6.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 KIK34945.1 - 1.2 9.8 9.1 5.5 7.7 8.6 2.2 1 1 1 2 2 2 0 SlyX OmpH PF03938.14 KIK34945.1 - 3.2 8.1 9.9 5.1 7.4 9.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Helicase_C PF00271.31 KIK34946.1 - 2e-22 79.6 0.3 3.8e-22 78.7 0.3 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK34946.1 - 1.7e-12 47.5 0.0 2.6e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-bind_6 PF13921.6 KIK34947.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain F-box-like PF12937.7 KIK34948.1 - 0.12 12.3 2.6 1.5 8.8 2.6 2.9 1 1 0 1 1 1 0 F-box-like Sec1 PF00995.23 KIK34949.1 - 4.1e-75 254.1 0.0 4.7e-75 253.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF913 PF06025.12 KIK34950.1 - 0.029 13.4 0.6 0.04 12.9 0.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ank_2 PF12796.7 KIK34951.1 - 3.3e-07 30.8 0.0 0.00089 19.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIK34951.1 - 0.00029 21.1 0.0 1.5 9.2 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KIK34951.1 - 0.018 15.6 0.1 0.12 13.0 0.1 2.2 1 1 2 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK34951.1 - 0.034 14.7 0.2 2.2 9.1 0.0 3.6 4 0 0 4 4 4 0 Ankyrin repeat eIF-1a PF01176.19 KIK34952.1 - 6.3e-23 80.4 0.1 9.2e-23 79.8 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 NPR3 PF03666.13 KIK34953.1 - 1.2e-91 307.8 1.6 1.9e-89 300.7 1.6 2.2 1 1 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 DUF2610 PF11020.8 KIK34953.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2610) Phosphoprotein PF00922.17 KIK34953.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Epimerase PF01370.21 KIK34955.1 - 1.3e-19 70.7 0.0 1.6e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK34955.1 - 5.6e-13 49.0 0.0 2.8e-11 43.4 0.0 2.2 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KIK34955.1 - 4.2e-10 39.1 0.0 5.5e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KIK34955.1 - 1.2e-07 31.9 0.0 2.3e-07 30.9 0.0 1.5 1 1 1 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KIK34955.1 - 5.8e-05 22.3 0.0 8.4e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DapB_N PF01113.20 KIK34955.1 - 0.036 14.2 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 KIK34955.1 - 0.08 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Ldh_1_N PF00056.23 KIK34955.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain HTH_8 PF02954.19 KIK34955.1 - 0.19 11.6 0.1 0.41 10.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family MBOAT_2 PF13813.6 KIK34956.1 - 6.6e-16 58.4 3.0 6.6e-16 58.4 3.0 3.0 4 0 0 4 4 4 1 Membrane bound O-acyl transferase family Peptidase_C7 PF01830.18 KIK34956.1 - 0.07 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase C7 family Plavaka PF18759.1 KIK34957.1 - 5.2e-65 219.8 0.4 9.9e-65 218.9 0.4 1.5 1 0 0 1 1 1 1 Plavaka transposase UBN_AB PF14075.6 KIK34959.1 - 0.003 17.3 0.0 0.003 17.3 0.0 1.0 1 0 0 1 1 1 1 Ubinuclein conserved middle domain Snapin_Pallidin PF14712.6 KIK34959.1 - 0.098 13.1 0.3 0.11 12.9 0.3 1.1 1 0 0 1 1 1 0 Snapin/Pallidin Glyco_hydro_38C PF07748.13 KIK34960.1 - 6.5e-12 46.0 0.0 9.6e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro_38C PF07748.13 KIK34961.1 - 3.8e-29 102.3 0.0 5.4e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro38C2 PF17677.1 KIK34961.1 - 1.1e-09 38.3 0.0 1.8e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Aldedh PF00171.22 KIK34962.1 - 1.8e-79 267.4 0.0 2.2e-79 267.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fic PF02661.18 KIK34962.1 - 0.0039 18.1 0.0 0.042 14.7 0.0 2.4 2 0 0 2 2 2 1 Fic/DOC family Sugar_tr PF00083.24 KIK34964.1 - 6.9e-90 302.1 22.2 8.4e-90 301.8 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK34964.1 - 5.1e-18 65.1 39.2 2.4e-15 56.3 13.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Tyr-DNA_phospho PF06087.12 KIK34965.1 - 1e-37 130.1 0.0 2e-37 129.1 0.0 1.5 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 KIK34965.1 - 0.039 13.8 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 PLD-like domain PLDc PF00614.22 KIK34965.1 - 0.18 12.1 0.4 38 4.7 0.0 3.0 3 0 0 3 3 3 0 Phospholipase D Active site motif UIM PF02809.20 KIK34966.1 - 6.9e-05 22.5 1.6 6.9e-05 22.5 1.6 2.9 3 0 0 3 3 3 1 Ubiquitin interaction motif F-box-like PF12937.7 KIK34967.1 - 0.0054 16.6 0.0 0.022 14.6 0.0 2.1 1 0 0 1 1 1 1 F-box-like GMC_oxred_N PF00732.19 KIK34968.1 - 1.3e-56 192.2 0.0 2.1e-56 191.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK34968.1 - 3.2e-28 99.1 0.0 6.4e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK34968.1 - 0.027 13.5 0.1 0.044 12.8 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK34968.1 - 0.065 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain MMR_HSR1 PF01926.23 KIK34969.1 - 5.4e-09 36.1 0.0 8.4e-09 35.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK34969.1 - 1.3e-05 25.2 0.0 5.9e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KIK34969.1 - 7.8e-05 22.8 0.2 0.00014 22.0 0.2 1.8 1 1 0 1 1 1 1 Dynamin family Roc PF08477.13 KIK34969.1 - 0.00041 20.5 0.1 0.01 16.0 0.0 2.4 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KIK34969.1 - 0.00062 20.3 0.1 0.00085 19.8 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AIG1 PF04548.16 KIK34969.1 - 0.0013 18.1 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 AIG1 family AAA_18 PF13238.6 KIK34969.1 - 0.0071 16.9 0.2 0.042 14.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KIK34969.1 - 0.0081 16.4 0.8 0.049 13.9 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KIK34969.1 - 0.0095 16.3 0.0 0.025 15.0 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 KIK34969.1 - 0.012 14.8 0.1 0.022 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 KIK34969.1 - 0.014 15.6 0.0 0.036 14.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 KIK34969.1 - 0.016 13.9 0.0 0.023 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KIK34969.1 - 0.018 14.8 0.0 0.52 10.1 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 KIK34969.1 - 0.087 12.6 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein dNK PF01712.19 KIK34969.1 - 0.096 12.5 0.0 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_29 PF13555.6 KIK34969.1 - 0.16 11.8 0.1 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KIK34969.1 - 0.39 11.2 0.3 0.39 11.2 0.3 1.9 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KIK34970.1 - 1.3e-11 44.6 0.0 2.9e-11 43.5 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK34970.1 - 1.1e-05 25.4 0.0 2.8e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 KIK34970.1 - 5e-05 23.5 0.0 0.00033 20.9 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KIK34970.1 - 7.6e-05 22.1 0.0 9.6e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 KIK34970.1 - 0.00013 21.7 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Ras family Dynamin_N PF00350.23 KIK34970.1 - 0.00039 20.5 0.0 0.00065 19.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin family AAA_22 PF13401.6 KIK34970.1 - 0.0021 18.3 0.0 0.0034 17.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KIK34970.1 - 0.0032 18.0 0.0 0.007 16.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KIK34970.1 - 0.004 17.5 0.0 0.011 16.2 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain Septin PF00735.18 KIK34970.1 - 0.038 13.3 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Septin FeoB_N PF02421.18 KIK34970.1 - 0.044 13.3 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B RNA_helicase PF00910.22 KIK34970.1 - 0.045 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 KIK34970.1 - 0.079 12.7 0.0 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KIK34970.1 - 0.12 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 KIK34970.1 - 0.17 10.9 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_18 PF13238.6 KIK34970.1 - 0.18 12.4 0.1 0.57 10.7 0.1 2.0 2 1 0 2 2 2 0 AAA domain Pkinase_Tyr PF07714.17 KIK34971.1 - 8.1e-12 45.0 0.0 8.5e-12 44.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK34971.1 - 5.5e-09 35.8 0.0 6.4e-09 35.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KIK34972.1 - 4e-23 82.1 0.0 4.7e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK34972.1 - 7.1e-21 74.7 0.0 8e-21 74.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK34972.1 - 4.8e-05 22.8 0.0 5.8e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIK34972.1 - 0.00016 21.7 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KIK34973.1 - 4.9e-07 29.3 0.0 5e-07 29.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK34973.1 - 0.0038 16.6 0.0 0.0043 16.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK34975.1 - 1.5e-25 89.9 0.0 1.7e-25 89.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK34975.1 - 1.4e-23 83.6 0.0 1.7e-23 83.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KIK34975.1 - 0.0002 20.8 0.0 0.00026 20.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIK34975.1 - 0.018 15.0 0.1 0.099 12.5 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.32 KIK34976.1 - 1.5e-11 44.6 0.1 1.4e-07 32.0 0.1 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK34976.1 - 0.033 14.5 0.0 0.037 14.3 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain QCR10 PF09796.9 KIK34977.1 - 0.13 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) HSP20 PF00011.21 KIK34979.1 - 1.7e-24 85.9 0.2 2.8e-24 85.2 0.2 1.4 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIK34979.1 - 5.2e-11 41.9 0.0 9.1e-11 41.2 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF4097 PF13349.6 KIK34979.1 - 0.0036 16.7 0.5 0.0045 16.4 0.5 1.1 1 0 0 1 1 1 1 Putative adhesin CS PF04969.16 KIK34979.1 - 0.0099 16.9 0.1 0.023 15.7 0.1 1.7 1 1 0 1 1 1 1 CS domain FKBP26_C PF18046.1 KIK34979.1 - 0.088 12.9 0.0 13 6.0 0.0 2.3 2 0 0 2 2 2 0 FKBP26_C-terminal BON PF04972.17 KIK34979.1 - 0.095 13.0 0.4 0.58 10.5 0.1 2.0 2 0 0 2 2 2 0 BON domain DUF1735 PF08522.10 KIK34979.1 - 0.14 12.8 0.0 0.19 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1735) F-box-like PF12937.7 KIK34980.1 - 2.6e-09 36.8 3.0 7.7e-09 35.3 3.0 1.8 1 0 0 1 1 1 1 F-box-like PhzC-PhzF PF02567.16 KIK34981.1 - 4e-33 115.1 0.0 4.5e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Proteasome_A_N PF10584.9 KIK34981.1 - 0.049 13.3 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Methyltransf_2 PF00891.18 KIK34982.1 - 3.9e-22 78.6 0.0 4.9e-20 71.7 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase domain STAS PF01740.21 KIK34982.1 - 0.021 14.4 0.0 0.042 13.5 0.0 1.6 1 1 0 1 1 1 0 STAS domain GMC_oxred_C PF05199.13 KIK34985.1 - 6.6e-32 111.0 0.0 1.3e-31 110.0 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase Arginosuc_synth PF00764.19 KIK34986.1 - 2.5e-154 514.3 0.0 2.9e-154 514.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KIK34986.1 - 0.00011 21.8 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KIK34986.1 - 0.032 13.0 0.0 0.062 12.1 0.0 1.5 1 1 0 1 1 1 0 tRNA methyl transferase Zn_ribbon_17 PF17120.5 KIK34987.1 - 2.7e-09 36.5 12.0 2.7e-09 36.5 12.0 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KIK34987.1 - 0.02 15.8 0.2 0.02 15.8 0.2 4.8 5 0 0 5 5 5 0 WD domain, G-beta repeat DZR PF12773.7 KIK34987.1 - 0.83 9.7 12.2 1.6 8.8 12.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon Tim44 PF04280.15 KIK34988.1 - 1.1e-33 116.4 0.3 2.3e-33 115.3 0.3 1.6 1 0 0 1 1 1 1 Tim44-like domain Transcrip_reg PF01709.20 KIK34988.1 - 0.0078 15.7 2.8 0.05 13.0 2.8 2.3 1 1 0 1 1 1 1 Transcriptional regulator Sigma54_CBD PF04963.13 KIK34988.1 - 0.011 15.6 0.0 0.71 9.7 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 factor, core binding domain CENP-O PF09496.10 KIK34988.1 - 0.019 15.0 1.1 0.019 15.0 1.1 1.9 3 0 0 3 3 3 0 Cenp-O kinetochore centromere component Collagen_mid PF15984.5 KIK34988.1 - 0.17 11.6 0.3 0.88 9.3 0.3 1.9 2 0 0 2 2 2 0 Bacterial collagen, middle region B277 PF17623.2 KIK34988.1 - 0.47 9.5 2.5 0.83 8.7 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF2203 PF09969.9 KIK34988.1 - 5.2 7.8 7.4 1.8 9.3 2.4 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Cyto_heme_lyase PF01265.17 KIK34992.1 - 9e-49 166.6 5.7 1.4e-47 162.8 5.7 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF2235 PF09994.9 KIK34993.1 - 9.1e-53 179.5 0.1 1.1e-52 179.2 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) RcnB PF11776.8 KIK34993.1 - 0.14 12.3 0.2 0.28 11.3 0.2 1.5 1 0 0 1 1 1 0 Nickel/cobalt transporter regulator BAAT_C PF08840.11 KIK34993.1 - 0.16 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal IIGP PF05049.13 KIK34995.1 - 1.5e-26 93.3 0.3 7.7e-26 91.0 0.3 1.8 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KIK34995.1 - 0.00019 21.5 0.0 0.00044 20.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ribosomal_S8 PF00410.19 KIK34995.1 - 0.064 13.2 0.4 0.11 12.5 0.4 1.3 1 0 0 1 1 1 0 Ribosomal protein S8 ABC_tran PF00005.27 KIK34995.1 - 0.14 12.7 1.4 0.81 10.2 1.4 2.2 1 1 0 1 1 1 0 ABC transporter Abhydrolase_1 PF00561.20 KIK34996.1 - 2.8e-25 89.4 0.3 2.1e-24 86.6 0.3 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK34996.1 - 2e-18 67.8 0.0 3e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK34996.1 - 3.5e-12 46.1 0.0 8.4e-09 35.0 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 KIK34996.1 - 5.8e-08 31.8 0.0 8.6e-08 31.2 0.0 1.6 1 1 0 1 1 1 1 Ndr family EHN PF06441.12 KIK34996.1 - 0.0028 18.0 0.2 0.0061 16.9 0.2 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_4 PF08386.10 KIK34996.1 - 0.071 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Btz PF09405.10 KIK34997.1 - 1.5e-10 41.4 5.3 1.5e-10 41.4 5.3 2.8 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding TFIIB PF00382.19 KIK34998.1 - 2e-34 117.4 0.0 2.5e-20 72.3 0.0 2.7 3 0 0 3 3 3 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KIK34998.1 - 8.4e-14 50.8 1.4 1.4e-13 50.1 1.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Guanylin PF02058.15 KIK34998.1 - 0.004 17.6 1.1 2.8 8.5 0.0 3.1 1 1 2 3 3 3 2 Guanylin precursor Cyclin_C PF02984.19 KIK34998.1 - 0.0046 17.0 0.0 0.23 11.5 0.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 KIK34998.1 - 0.072 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain RB_B PF01857.20 KIK34998.1 - 0.072 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain RRS1 PF04939.12 KIK34999.1 - 2.1e-59 200.0 4.9 3.6e-59 199.2 4.9 1.4 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) TonB_N PF16031.5 KIK34999.1 - 8.8 6.8 15.9 18 5.9 6.9 2.5 2 0 0 2 2 2 0 TonB polyproline region TAF4 PF05236.14 KIK35000.1 - 4.1e-37 128.4 1.7 5.7e-37 128.0 1.7 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family SSP160 PF06933.11 KIK35000.1 - 0.61 8.2 12.1 1.3 7.1 12.1 1.5 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PhzC-PhzF PF02567.16 KIK35001.1 - 1.1e-30 107.1 0.0 1.3e-30 106.9 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Proteasome_A_N PF10584.9 KIK35001.1 - 0.043 13.5 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature F-box-like PF12937.7 KIK35002.1 - 1.1e-10 41.2 3.8 3e-10 39.8 3.8 1.8 1 0 0 1 1 1 1 F-box-like DUF4942 PF13708.6 KIK35002.1 - 0.11 12.4 0.1 9.5 6.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4942) FUSC PF04632.12 KIK35003.1 - 0.029 12.9 0.4 0.041 12.4 0.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FGGY_C PF02782.16 KIK35006.1 - 1.6e-23 83.5 0.2 2.4e-23 82.9 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain AnmK PF03702.14 KIK35006.1 - 0.006 15.7 0.1 0.0081 15.3 0.1 1.2 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Rossmann-like PF10727.9 KIK35006.1 - 0.051 13.4 0.8 0.094 12.6 0.8 1.4 1 0 0 1 1 1 0 Rossmann-like domain DUF3479 PF11965.8 KIK35006.1 - 0.099 12.8 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) Plavaka PF18759.1 KIK35008.1 - 6.9e-130 433.0 0.0 9.5e-130 432.5 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase TyeA PF09059.10 KIK35010.1 - 0.077 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 TyeA MSA-2c PF12238.8 KIK35010.1 - 0.48 10.4 2.1 0.64 10.0 2.1 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c WD40 PF00400.32 KIK35012.1 - 3.3e-19 68.9 4.1 5.8e-06 26.9 0.0 5.5 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35012.1 - 3.7e-06 27.1 0.0 0.031 14.6 0.0 3.6 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK35012.1 - 0.065 11.9 2.4 0.43 9.2 0.1 2.7 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Aldedh PF00171.22 KIK35013.1 - 5.3e-47 160.4 1.8 2.7e-33 115.2 0.3 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Na_Ca_ex PF01699.24 KIK35013.1 - 1.3e-19 70.6 26.1 1.1e-11 44.9 5.7 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein EFG_C PF00679.24 KIK35013.1 - 1.1e-17 63.8 0.0 2.6e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus RdRP_2 PF00978.21 KIK35016.1 - 0.14 11.1 0.0 0.14 11.0 0.0 1.0 1 0 0 1 1 1 0 RNA dependent RNA polymerase Pkinase PF00069.25 KIK35017.1 - 2.4e-22 79.6 0.0 3e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK35017.1 - 1.4e-12 47.5 0.0 1.9e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK35017.1 - 2.5e-08 33.1 0.0 3.5e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK35017.1 - 0.0034 17.3 0.5 0.063 13.2 0.2 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KIK35017.1 - 0.011 14.8 0.3 0.016 14.2 0.3 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KIK35017.1 - 0.11 11.8 0.3 0.17 11.2 0.3 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KIK35017.1 - 0.22 11.0 0.2 0.34 10.5 0.2 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Herpes_Helicase PF02689.14 KIK35018.1 - 0.00066 17.7 0.0 0.00071 17.6 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KIK35018.1 - 0.002 17.9 0.1 0.0055 16.5 0.1 1.8 1 1 1 2 2 2 1 UvrD-like helicase C-terminal domain PIF1 PF05970.14 KIK35019.1 - 2.4e-07 30.3 0.0 2.4e-07 30.3 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase PIF1 PF05970.14 KIK35020.1 - 1.8e-16 60.3 0.0 1.9e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase PIF1 PF05970.14 KIK35021.1 - 1.8e-22 80.1 0.0 2.1e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.15 KIK35021.1 - 0.018 15.1 0.0 0.024 14.7 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KIK35021.1 - 0.02 14.6 0.0 0.027 14.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KIK35021.1 - 0.032 14.7 0.1 0.048 14.1 0.1 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK35021.1 - 0.035 14.5 0.1 0.052 13.9 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 KIK35021.1 - 0.042 13.6 0.2 0.064 13.0 0.2 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 KIK35021.1 - 0.074 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Torsin PF06309.11 KIK35021.1 - 0.091 12.9 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Torsin ABC_tran PF00005.27 KIK35021.1 - 0.13 12.8 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 KIK35021.1 - 0.21 11.5 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Helitron_like_N PF14214.6 KIK35023.1 - 1.3e-48 165.7 0.0 1.5e-48 165.5 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF5588 PF17826.1 KIK35024.1 - 0.091 11.6 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5588) HNH_2 PF13391.6 KIK35029.1 - 0.0067 16.5 0.3 0.033 14.3 0.2 2.1 2 0 0 2 2 2 1 HNH endonuclease DUF3140 PF11338.8 KIK35029.1 - 0.03 14.7 0.9 12 6.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3140) WD40 PF00400.32 KIK35033.1 - 0.017 16.0 0.0 0.04 14.8 0.0 1.6 1 0 0 1 1 1 0 WD domain, G-beta repeat Pkinase_fungal PF17667.1 KIK35035.1 - 1.8e-39 135.7 0.0 1e-21 77.2 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIK35035.1 - 2.3e-05 23.9 0.0 3.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK35035.1 - 0.03 14.2 0.1 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3027 PF11228.8 KIK35035.1 - 0.053 13.5 0.0 0.074 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) ATP-synt_C PF00137.21 KIK35036.1 - 1.5e-07 31.7 4.1 1.8e-07 31.4 4.1 1.2 1 0 0 1 1 1 1 ATP synthase subunit C RIX1 PF08167.12 KIK35038.1 - 0.058 13.1 0.0 0.067 12.9 0.0 1.1 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis WD40 PF00400.32 KIK35040.1 - 4.1e-14 52.7 0.1 1.5e-06 28.8 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35040.1 - 0.0001 22.5 0.0 0.096 13.0 0.0 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Sortilin_C PF15901.5 KIK35041.1 - 0.23 11.8 0.0 0.36 11.2 0.0 1.3 1 0 0 1 1 1 0 Sortilin, neurotensin receptor 3, C-terminal WD40 PF00400.32 KIK35042.1 - 9.4e-09 35.8 2.8 0.53 11.3 0.2 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35042.1 - 2.5e-07 30.9 0.0 0.00062 20.0 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK35042.1 - 8.8e-07 28.2 0.1 0.025 13.6 0.0 2.3 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TruB_C PF09142.11 KIK35042.1 - 0.015 15.1 0.2 6.3 6.7 0.1 2.9 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal Cas_csx3 PF09620.10 KIK35042.1 - 0.09 12.7 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) CCSAP PF15748.5 KIK35042.1 - 0.1 12.8 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Cytochrom_D1 PF02239.16 KIK35042.1 - 0.25 9.8 0.5 6 5.3 0.1 2.5 2 1 1 3 3 3 0 Cytochrome D1 heme domain Sortilin-Vps10 PF15902.5 KIK35044.1 - 2.9e-44 151.6 0.2 3.8e-44 151.2 0.2 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KIK35044.1 - 3.9e-43 147.7 2.5 3.9e-43 147.7 2.5 1.8 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, C-terminal MHB PF16525.5 KIK35045.1 - 0.06 13.6 2.1 0.38 11.0 0.2 3.3 4 1 0 4 4 4 0 Haemophore, haem-binding CBFD_NFYB_HMF PF00808.23 KIK35045.1 - 0.18 12.1 1.9 0.44 10.9 1.9 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cauli_VI PF01693.16 KIK35046.1 - 1e-09 38.6 0.3 3e-09 37.0 0.2 1.9 2 0 0 2 2 2 1 Caulimovirus viroplasmin Moulting_cycle PF04870.16 KIK35047.1 - 0.042 13.1 0.0 0.05 12.9 0.0 1.0 1 0 0 1 1 1 0 Moulting cycle KDZ PF18758.1 KIK35048.1 - 2.4e-64 217.0 0.0 3.7e-64 216.4 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK35048.1 - 2.2e-44 150.0 0.1 5.1e-44 148.8 0.1 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK35048.1 - 0.00021 21.4 0.9 0.00063 19.9 0.1 2.2 3 0 0 3 3 3 1 CxC1 like cysteine cluster associated with KDZ transposases CHAT PF12770.7 KIK35052.1 - 3.6e-17 62.7 0.0 4e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 CHAT domain FSIP2 PF15783.5 KIK35052.1 - 0.015 13.3 0.0 0.017 13.1 0.0 1.0 1 0 0 1 1 1 0 Fibrous sheath-interacting protein 2 CxC5 PF18718.1 KIK35053.1 - 1.1e-39 135.2 2.3 3e-39 133.7 2.3 1.7 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 KIK35053.1 - 7.1e-09 35.8 1.3 7.1e-09 35.8 1.3 2.9 3 1 0 3 3 3 1 CxC6 like cysteine cluster associated with KDZ transposases WD40 PF00400.32 KIK35054.1 - 6.3e-10 39.5 0.2 6.9e-06 26.7 0.2 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35054.1 - 0.021 15.1 0.0 1.1 9.6 0.0 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Big_3_5 PF16640.5 KIK35054.1 - 0.1 12.8 2.0 7.6 6.8 0.1 2.1 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 3) RVT_2 PF07727.14 KIK35055.1 - 3.7e-05 23.5 0.0 3.8e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Plavaka PF18759.1 KIK35056.1 - 1e-62 212.3 0.3 4.6e-33 114.8 0.0 3.2 2 1 1 3 3 3 3 Plavaka transposase Importin_rep_4 PF18808.1 KIK35057.1 - 0.097 13.0 0.1 0.43 10.9 0.0 1.9 2 1 0 2 2 2 0 Importin repeat zf-RING_2 PF13639.6 KIK35060.1 - 0.0052 17.1 13.9 0.0052 17.1 13.9 2.3 2 0 0 2 2 2 1 Ring finger domain C1_1 PF00130.22 KIK35060.1 - 0.026 14.4 7.5 0.026 14.4 7.5 2.1 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 KIK35060.1 - 0.031 14.2 12.5 0.084 12.8 12.5 1.8 1 1 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 KIK35060.1 - 0.16 11.9 11.2 0.16 11.9 9.7 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 ABC_tran PF00005.27 KIK35062.1 - 7.9e-26 91.2 0.0 1.6e-25 90.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIK35062.1 - 6.6e-08 32.7 0.1 0.00015 21.7 0.2 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIK35062.1 - 2.1e-06 27.3 0.4 0.057 12.9 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KIK35062.1 - 0.00011 22.1 0.1 0.00037 20.3 0.1 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KIK35062.1 - 0.00013 22.5 0.4 0.00028 21.5 0.4 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIK35062.1 - 0.00034 20.4 0.0 0.0051 16.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIK35062.1 - 0.0011 18.6 0.1 0.0026 17.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KIK35062.1 - 0.0016 18.9 0.1 0.0063 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIK35062.1 - 0.0027 18.0 0.4 0.066 13.5 0.0 3.0 3 1 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KIK35062.1 - 0.0056 16.9 0.2 0.07 13.4 0.1 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KIK35062.1 - 0.0077 16.2 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Ploopntkinase3 PF18751.1 KIK35062.1 - 0.009 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 KIK35062.1 - 0.018 15.4 0.0 0.07 13.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KIK35062.1 - 0.019 14.3 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_27 PF13514.6 KIK35062.1 - 0.053 13.1 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KIK35062.1 - 0.053 12.7 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit CdiI_3 PF18616.1 KIK35062.1 - 0.072 13.0 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 CDI immunity proteins FtsK_SpoIIIE PF01580.18 KIK35062.1 - 0.099 12.0 0.1 0.28 10.5 0.1 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.6 KIK35062.1 - 0.11 12.7 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KIK35062.1 - 0.13 12.3 0.0 0.46 10.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KIK35062.1 - 0.18 11.4 0.0 0.86 9.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain NUC129 PF08157.11 KIK35063.1 - 0.13 12.6 1.2 0.19 12.1 0.3 1.8 2 0 0 2 2 2 0 NUC129 domain SelR PF01641.18 KIK35068.1 - 8.1e-52 174.4 0.1 9.2e-52 174.2 0.1 1.0 1 0 0 1 1 1 1 SelR domain ADD_ATRX PF17981.1 KIK35068.1 - 0.0014 18.4 0.1 0.066 13.1 0.0 2.2 2 0 0 2 2 2 1 Cysteine Rich ADD domain GFA PF04828.14 KIK35068.1 - 0.017 15.5 0.3 0.21 12.0 0.0 2.1 1 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Yippee-Mis18 PF03226.14 KIK35068.1 - 0.024 14.8 0.2 0.065 13.4 0.2 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-Mss51 PF13824.6 KIK35068.1 - 0.036 14.2 2.4 0.44 10.7 0.8 2.8 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 DZR PF12773.7 KIK35068.1 - 0.062 13.3 3.2 0.81 9.8 3.2 2.2 1 1 1 2 2 2 0 Double zinc ribbon DUF678 PF05077.12 KIK35068.1 - 0.13 12.4 0.1 10 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF678) Tropomyosin_1 PF12718.7 KIK35069.1 - 2.2e-49 167.3 31.6 2.6e-49 167.1 31.6 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KIK35069.1 - 1.6e-13 50.6 29.8 1.7e-06 27.6 8.6 3.0 1 1 2 3 3 3 3 Tropomyosin DUF1664 PF07889.12 KIK35069.1 - 4.1e-05 23.6 7.6 4.1e-05 23.6 7.6 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) GAS PF13851.6 KIK35069.1 - 0.00016 21.1 33.0 0.0019 17.6 12.7 2.0 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding KLRAQ PF10205.9 KIK35069.1 - 0.00052 20.2 3.6 0.00052 20.2 3.6 3.3 1 1 2 3 3 3 1 Predicted coiled-coil domain-containing protein Uso1_p115_C PF04871.13 KIK35069.1 - 0.00056 20.3 32.8 0.00057 20.3 16.4 2.1 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region CCDC-167 PF15188.6 KIK35069.1 - 0.00087 19.6 5.9 0.00087 19.6 5.9 2.9 1 1 2 3 3 3 1 Coiled-coil domain-containing protein 167 CLZ PF16526.5 KIK35069.1 - 0.0015 18.8 25.6 0.017 15.5 5.8 3.4 1 1 2 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels KELK PF15796.5 KIK35069.1 - 0.0022 18.4 6.9 0.0022 18.4 6.9 3.7 1 1 1 3 3 2 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3450 PF11932.8 KIK35069.1 - 0.0025 17.2 28.3 0.12 11.7 17.9 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) EzrA PF06160.12 KIK35069.1 - 0.0028 15.9 15.5 0.0028 15.9 15.5 2.1 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA Transketolase_N PF00456.21 KIK35069.1 - 0.006 15.6 7.7 0.0077 15.2 7.7 1.0 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain ADIP PF11559.8 KIK35069.1 - 0.0068 16.5 25.8 0.22 11.6 5.3 3.2 1 1 2 3 3 3 2 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 KIK35069.1 - 0.015 15.3 32.9 0.091 12.8 12.7 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.6 KIK35069.1 - 0.019 15.4 35.1 0.67 10.4 9.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Seryl_tRNA_N PF02403.22 KIK35069.1 - 0.023 14.9 27.8 0.019 15.2 15.3 2.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HrpB7 PF09486.10 KIK35069.1 - 0.023 15.1 21.7 0.13 12.6 4.5 2.8 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) FliJ PF02050.16 KIK35069.1 - 0.024 14.8 27.0 0.62 10.3 5.6 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein Rab5-bind PF09311.11 KIK35069.1 - 0.027 13.8 24.1 0.073 12.5 9.1 2.3 1 1 1 2 2 2 0 Rabaptin-like protein DHR10 PF18595.1 KIK35069.1 - 0.035 14.1 31.6 0.91 9.6 9.0 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Baculo_PEP_C PF04513.12 KIK35069.1 - 0.043 13.9 6.5 0.15 12.1 3.0 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BRE1 PF08647.11 KIK35069.1 - 0.054 13.6 33.0 0.21 11.7 8.1 2.8 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.12 KIK35069.1 - 0.064 13.3 33.1 0.7 10.0 9.3 3.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein KxDL PF10241.9 KIK35069.1 - 0.069 13.4 23.2 0.13 12.6 5.7 3.1 1 1 2 3 3 3 0 Uncharacterized conserved protein Snapin_Pallidin PF14712.6 KIK35069.1 - 0.076 13.4 18.8 0.071 13.5 10.9 3.5 2 1 1 3 3 3 0 Snapin/Pallidin HGD-D PF06050.13 KIK35069.1 - 0.081 12.7 4.8 0.066 13.0 3.5 1.4 1 1 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component CENP-F_leu_zip PF10473.9 KIK35069.1 - 0.096 12.7 32.1 0.075 13.1 10.8 2.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG17 PF04108.12 KIK35069.1 - 0.11 11.6 19.6 0.06 12.5 3.0 3.0 1 1 2 3 3 3 0 Autophagy protein Apg17 FliD_C PF07195.12 KIK35069.1 - 0.12 11.7 20.0 0.14 11.6 4.6 3.0 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Laminin_II PF06009.12 KIK35069.1 - 0.2 11.7 19.5 0.079 13.0 9.6 2.2 1 1 1 2 2 2 0 Laminin Domain II BLOC1_2 PF10046.9 KIK35069.1 - 0.28 11.5 25.6 0.23 11.8 7.3 3.3 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6_N PF17675.1 KIK35069.1 - 0.36 11.4 36.5 0.09 13.3 24.9 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region ATG16 PF08614.11 KIK35069.1 - 0.36 11.0 28.3 0.53 10.5 18.1 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4164 PF13747.6 KIK35069.1 - 0.36 11.1 22.6 1.7 9.0 7.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF2408 PF10303.9 KIK35069.1 - 0.37 11.4 21.8 1.3 9.6 9.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Jnk-SapK_ap_N PF09744.9 KIK35069.1 - 0.39 10.9 30.9 0.19 12.0 14.2 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 FAP206 PF12018.8 KIK35069.1 - 0.43 10.0 13.6 0.071 12.6 9.5 1.7 1 1 1 2 2 2 0 Domain of unknown function TINF2_N PF14973.6 KIK35069.1 - 0.44 10.9 13.0 0.34 11.2 5.3 2.4 1 1 2 3 3 2 0 TERF1-interacting nuclear factor 2 N-terminus HHV-5_US34A PF17087.5 KIK35069.1 - 0.45 10.7 6.3 0.096 12.8 2.5 1.9 2 1 0 2 2 1 0 Herpesvirus US34A protein family HMMR_N PF15905.5 KIK35069.1 - 0.47 9.9 30.8 0.65 9.4 30.8 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal RasGAP_C PF03836.15 KIK35069.1 - 0.5 10.5 15.2 0.48 10.6 12.5 2.1 1 1 1 2 2 2 0 RasGAP C-terminus ERM PF00769.19 KIK35069.1 - 0.51 10.1 35.2 0.44 10.3 30.5 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Nsp1_C PF05064.13 KIK35069.1 - 0.69 9.7 20.0 0.27 11.1 4.9 2.9 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF3584 PF12128.8 KIK35069.1 - 0.69 7.3 27.6 0.85 7.1 27.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF812 PF05667.11 KIK35069.1 - 0.76 8.6 30.1 1.7 7.5 30.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) ArAE_2_N PF10337.9 KIK35069.1 - 0.86 8.6 6.1 0.99 8.4 6.1 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF4795 PF16043.5 KIK35069.1 - 0.88 9.1 28.1 1 8.9 28.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) AAA_13 PF13166.6 KIK35069.1 - 0.9 8.1 25.2 2.6 6.6 25.2 1.6 1 1 0 1 1 1 0 AAA domain MAD PF05557.13 KIK35069.1 - 0.93 7.8 29.5 0.12 10.7 18.5 1.9 1 1 1 2 2 2 0 Mitotic checkpoint protein Phage_GP20 PF06810.11 KIK35069.1 - 0.98 9.2 26.9 0.37 10.6 12.1 2.9 1 1 2 3 3 3 0 Phage minor structural protein GP20 TMF_TATA_bd PF12325.8 KIK35069.1 - 1 9.6 27.7 0.66 10.2 11.4 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding GrpE PF01025.19 KIK35069.1 - 1 9.0 34.3 0.27 10.9 5.5 3.9 1 1 3 4 4 4 0 GrpE Fez1 PF06818.15 KIK35069.1 - 1 9.7 25.9 4 7.8 25.9 1.8 1 1 0 1 1 1 0 Fez1 Occludin_ELL PF07303.13 KIK35069.1 - 1.3 9.7 19.7 1.2 9.9 2.2 3.2 1 1 2 3 3 3 0 Occludin homology domain FAM76 PF16046.5 KIK35069.1 - 1.4 8.2 21.8 33 3.7 21.8 2.1 1 1 0 1 1 1 0 FAM76 protein NPV_P10 PF05531.12 KIK35069.1 - 1.6 9.3 11.4 62 4.2 1.0 3.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 KIK35069.1 - 1.7 9.0 15.6 1.7 8.9 2.6 3.3 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) YscO PF07321.12 KIK35069.1 - 1.8 8.5 29.2 1.9e+02 1.9 29.2 2.3 1 1 0 1 1 1 0 Type III secretion protein YscO WXG100 PF06013.12 KIK35069.1 - 1.9 8.8 17.2 0.65 10.3 3.5 3.7 1 1 4 5 5 5 0 Proteins of 100 residues with WXG Cluap1 PF10234.9 KIK35069.1 - 1.9 7.8 25.1 3.9 6.8 6.3 2.3 1 1 1 2 2 2 0 Clusterin-associated protein-1 Syntaxin_2 PF14523.6 KIK35069.1 - 2 8.9 17.4 0.57 10.6 12.8 2.1 1 1 1 2 2 2 0 Syntaxin-like protein Spc7 PF08317.11 KIK35069.1 - 2 7.2 31.1 0.37 9.6 17.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Dynamitin PF04912.14 KIK35069.1 - 2 7.6 25.8 46 3.2 25.8 2.6 1 1 0 1 1 1 0 Dynamitin HalX PF08663.10 KIK35069.1 - 2.2 8.7 16.7 14 6.1 0.1 4.1 2 1 2 4 4 4 0 HalX domain Lectin_N PF03954.14 KIK35069.1 - 2.4 7.9 12.9 4.4 7.0 2.7 3.0 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain T3SSipB PF16535.5 KIK35069.1 - 2.5 8.6 22.0 1.5 9.3 13.9 2.1 1 1 1 2 2 2 0 Type III cell invasion protein SipB HisKA_3 PF07730.13 KIK35069.1 - 2.5 8.7 12.5 8.9 6.9 0.3 3.5 2 1 1 3 3 2 0 Histidine kinase DUF4201 PF13870.6 KIK35069.1 - 2.9 7.6 27.7 1 9.1 14.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Swi5 PF07061.11 KIK35069.1 - 3 8.0 24.6 2.4 8.3 1.9 3.9 1 1 2 3 3 3 0 Swi5 DUF724 PF05266.14 KIK35069.1 - 3.1 7.6 29.5 2 8.2 14.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) HAUS-augmin3 PF14932.6 KIK35069.1 - 3.1 7.3 22.4 0.96 9.0 19.1 1.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 TMPIT PF07851.13 KIK35069.1 - 3.1 7.0 22.4 1.8 7.7 13.1 2.0 1 1 1 2 2 2 0 TMPIT-like protein LIN37 PF15306.6 KIK35069.1 - 3.1 8.0 13.5 7.6 6.7 13.5 1.7 1 1 0 1 1 1 0 LIN37 Tup_N PF08581.10 KIK35069.1 - 3.6 8.0 27.1 0.29 11.5 5.9 2.8 1 1 2 3 3 3 0 Tup N-terminal FapA PF03961.13 KIK35069.1 - 3.9 6.0 25.4 0.082 11.5 12.3 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A ABC_tran_CTD PF16326.5 KIK35069.1 - 4 7.8 29.7 1.3 9.4 10.8 3.8 1 1 3 4 4 4 0 ABC transporter C-terminal domain FUSC PF04632.12 KIK35069.1 - 4.7 5.6 5.7 4.5 5.7 5.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.6 KIK35069.1 - 4.7 6.5 23.6 7.2 5.9 8.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF2203 PF09969.9 KIK35069.1 - 4.8 7.9 21.6 1.8 9.3 5.5 2.8 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) OmpH PF03938.14 KIK35069.1 - 5.2 7.4 34.0 7.2 6.9 22.7 2.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 KIK35069.1 - 5.2 7.8 21.4 0.57 10.8 2.1 3.6 1 1 3 4 4 3 0 SlyX Atg14 PF10186.9 KIK35069.1 - 5.3 6.0 23.2 0.32 10.0 11.5 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 LMBR1 PF04791.16 KIK35069.1 - 5.8 5.7 21.1 8.9 5.1 21.1 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein Prefoldin_2 PF01920.20 KIK35069.1 - 5.8 6.9 31.0 2 8.4 5.8 3.9 1 1 3 4 4 4 0 Prefoldin subunit ZapB PF06005.12 KIK35069.1 - 6.4 7.3 32.6 0.43 11.1 7.5 3.7 1 1 3 4 4 4 0 Cell division protein ZapB V_ATPase_I PF01496.19 KIK35069.1 - 6.7 4.5 20.8 5.2 4.8 19.2 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CorA PF01544.18 KIK35069.1 - 6.8 5.9 11.2 10 5.3 11.2 1.3 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Fib_alpha PF08702.10 KIK35069.1 - 6.9 6.9 20.9 2 8.6 8.8 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PI3K_P85_iSH2 PF16454.5 KIK35069.1 - 7.1 6.2 26.4 6.5 6.3 18.3 2.4 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain IZUMO PF15005.6 KIK35069.1 - 7.1 7.1 13.1 2.8 8.4 10.1 1.8 1 1 1 2 2 1 0 Izumo sperm-egg fusion, Ig domain-associated DUF2802 PF10975.8 KIK35069.1 - 7.3 6.8 19.0 27 5.0 0.2 4.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2802) UPF0242 PF06785.11 KIK35069.1 - 7.9 6.5 30.1 2.2 8.3 18.2 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 KIK35069.1 - 8 7.0 22.8 31 5.1 10.1 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF2408 PF10303.9 KIK35070.1 - 6.6e-60 201.5 7.0 3e-41 141.1 0.3 5.1 4 1 1 5 5 5 4 Protein of unknown function (DUF2408) DED PF01335.21 KIK35070.1 - 0.032 14.5 0.1 0.33 11.3 0.0 2.7 2 0 0 2 2 2 0 Death effector domain Attractin PF08037.11 KIK35070.1 - 0.055 13.5 2.3 5.3 7.1 0.2 2.6 2 0 0 2 2 2 0 Attractin family Baculo_PEP_C PF04513.12 KIK35070.1 - 0.14 12.2 2.3 18 5.3 0.0 3.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF724 PF05266.14 KIK35070.1 - 0.16 11.8 3.8 0.089 12.6 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Med9 PF07544.13 KIK35070.1 - 0.22 11.7 0.2 0.22 11.7 0.2 3.7 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Trns_repr_metal PF02583.17 KIK35070.1 - 0.22 11.9 1.5 40 4.7 0.1 3.8 5 0 0 5 5 5 0 Metal-sensitive transcriptional repressor EzrA PF06160.12 KIK35070.1 - 0.23 9.6 4.0 1.6 6.8 0.9 2.4 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA ZapA PF05164.13 KIK35070.1 - 0.28 11.6 0.0 0.28 11.6 0.0 3.5 3 1 0 3 3 3 0 Cell division protein ZapA Mo25 PF08569.11 KIK35070.1 - 1.5 8.1 5.6 0.15 11.4 0.6 1.9 2 1 0 2 2 2 0 Mo25-like DUF4446 PF14584.6 KIK35070.1 - 1.6 8.7 4.4 4.6 7.2 0.1 3.3 3 1 0 4 4 4 0 Protein of unknown function (DUF4446) COG2 PF06148.11 KIK35070.1 - 1.7 8.7 8.4 19 5.4 0.2 4.2 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Hrs_helical PF12210.8 KIK35070.1 - 5.4 7.6 6.3 13 6.4 0.1 3.6 4 0 0 4 4 4 0 Hepatocyte growth factor-regulated tyrosine kinase substrate ATP-synt_ab PF00006.25 KIK35071.1 - 6.7e-73 244.9 0.0 1.1e-72 244.1 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KIK35071.1 - 4.3e-43 146.6 0.0 7.2e-43 145.9 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KIK35071.1 - 9.8e-18 64.5 1.2 2.3e-17 63.3 1.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Ribosomal_L21p PF00829.21 KIK35072.1 - 6.7e-25 87.3 0.4 8.2e-25 87.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein UvrA_inter PF17760.1 KIK35072.1 - 0.045 13.8 0.1 0.071 13.2 0.1 1.3 1 0 0 1 1 1 0 UvrA interaction domain FF PF01846.19 KIK35073.1 - 5.7e-33 112.9 7.2 3e-11 43.3 0.0 6.3 6 1 0 6 6 6 5 FF domain WW PF00397.26 KIK35073.1 - 8.3e-12 45.0 16.0 2e-06 27.7 4.7 2.7 2 0 0 2 2 2 2 WW domain zf-RVT PF13966.6 KIK35074.1 - 7.4e-05 23.4 0.3 0.0001 23.0 0.3 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase ketoacyl-synt PF00109.26 KIK35075.1 - 1.2e-55 188.9 0.0 3.1e-55 187.5 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIK35075.1 - 2.7e-44 152.0 0.0 4.7e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KIK35075.1 - 8.5e-39 133.3 0.0 5.5e-36 124.2 0.0 2.5 2 0 0 2 2 2 2 KR domain NAD_binding_4 PF07993.12 KIK35075.1 - 2.8e-31 108.6 0.0 4.2e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PS-DH PF14765.6 KIK35075.1 - 4.8e-29 101.6 0.0 9.2e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KIK35075.1 - 2.3e-27 95.3 0.0 5.5e-27 94.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KIK35075.1 - 8.7e-10 39.1 0.0 2.6e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 KIK35075.1 - 1e-09 38.2 0.0 2.8e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIK35075.1 - 3.6e-07 30.4 0.3 9.5e-07 29.1 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KIK35075.1 - 0.0003 20.2 0.1 0.0018 17.7 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KIK35075.1 - 0.0077 16.1 0.1 0.039 13.8 0.1 2.2 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Polysacc_synt_2 PF02719.15 KIK35075.1 - 0.015 14.5 0.0 0.22 10.6 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KIK35075.1 - 0.025 14.7 0.0 3.8 7.6 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 KIK35075.1 - 0.026 13.9 0.0 0.1 11.9 0.0 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 KIK35075.1 - 0.16 12.4 0.1 0.49 10.9 0.0 1.9 2 0 0 2 2 1 0 Semialdehyde dehydrogenase, NAD binding domain PCRF PF03462.18 KIK35075.1 - 0.16 11.8 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 PCRF domain MFS_1 PF07690.16 KIK35076.1 - 2e-29 102.6 72.6 7e-21 74.5 42.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK35076.1 - 0.00046 19.2 42.9 0.00086 18.3 15.7 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter Tri3 PF07428.11 KIK35077.1 - 4.3e-13 49.0 0.0 1.1e-12 47.7 0.0 1.5 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 Ins134_P3_kin PF05770.11 KIK35078.1 - 0.095 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain TPR_10 PF13374.6 KIK35079.1 - 1.7e-42 142.2 40.1 0.0025 17.6 0.1 13.2 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_12 PF13424.6 KIK35079.1 - 3.3e-14 52.9 39.9 0.18 12.1 1.6 13.5 2 1 13 15 15 15 6 Tetratricopeptide repeat GATase_4 PF13230.6 KIK35079.1 - 4.3e-12 45.5 6.9 0.023 13.6 0.0 6.8 3 1 5 8 8 8 5 Glutamine amidotransferases class-II DUF4471 PF14740.6 KIK35079.1 - 6.2e-07 28.9 0.0 11 5.1 0.0 7.7 10 0 0 10 10 10 2 Domain of unknown function (DUF4471) TPR_14 PF13428.6 KIK35079.1 - 7.3e-05 23.3 23.9 2.9 9.0 0.5 9.6 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK35079.1 - 0.0007 19.6 9.6 27 5.3 0.0 8.7 11 0 0 11 11 11 0 Tetratricopeptide repeat Fer4_13 PF13370.6 KIK35079.1 - 0.024 15.2 0.1 47 4.6 0.0 4.3 4 0 0 4 4 4 0 4Fe-4S single cluster domain of Ferredoxin I DUF4253 PF14062.6 KIK35079.1 - 0.076 13.2 0.2 40 4.4 0.0 4.6 4 2 0 4 4 4 0 Domain of unknown function (DUF4253) DUF2783 PF10932.8 KIK35079.1 - 1.2 8.9 12.7 14 5.5 0.1 6.0 7 0 0 7 7 7 0 Protein of unknown function (DUF2783) TPR_14 PF13428.6 KIK35080.1 - 2.4e-05 24.8 0.8 0.043 14.7 0.2 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK35080.1 - 0.00046 20.4 0.0 0.0086 16.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK35080.1 - 0.00081 19.3 0.0 0.3 11.3 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK35080.1 - 0.0045 16.8 0.0 0.36 10.7 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK35080.1 - 0.18 11.5 0.0 1.3 8.8 0.0 2.3 2 1 0 2 2 2 0 TPR repeat Ank_2 PF12796.7 KIK35082.1 - 2.6e-11 44.0 0.4 4.9e-08 33.5 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KIK35082.1 - 5.1e-09 36.2 0.9 0.0025 18.2 0.8 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KIK35082.1 - 8.6e-08 32.3 0.7 4.8e-06 26.7 0.8 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KIK35082.1 - 7.6e-06 26.4 0.1 0.017 15.7 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK35082.1 - 2.8e-05 24.1 1.0 0.021 15.4 0.1 4.1 3 2 0 3 3 3 1 Ankyrin repeat Pkinase PF00069.25 KIK35083.1 - 1.6e-32 112.9 0.0 8.6e-32 110.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK35083.1 - 7.8e-15 54.8 0.0 1.3e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK35083.1 - 0.16 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KIK35083.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK35083.1 - 0.25 10.1 0.0 0.4 9.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SMC_N PF02463.19 KIK35084.1 - 2.1e-73 246.4 0.2 4.5e-73 245.3 0.2 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KIK35084.1 - 4.7e-24 84.9 0.0 1.5e-23 83.3 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KIK35084.1 - 2e-12 47.6 9.0 3.9e-06 26.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIK35084.1 - 1.6e-10 41.2 0.0 1.6e-10 41.2 0.0 4.2 3 2 0 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 KIK35084.1 - 2.1e-05 24.1 0.4 4.5e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain HTH_46 PF15977.5 KIK35084.1 - 0.11 12.5 0.4 9.3 6.3 0.0 3.3 3 0 0 3 3 3 0 Winged helix-turn-helix DNA binding DUF4632 PF15451.6 KIK35084.1 - 0.19 11.8 0.0 0.19 11.8 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4632) ABC_tran PF00005.27 KIK35084.1 - 0.95 10.0 0.0 0.95 10.0 0.0 5.9 4 3 0 4 4 4 0 ABC transporter MbeD_MobD PF04899.12 KIK35084.1 - 1 9.5 11.8 2.6 8.2 0.5 4.3 3 0 0 3 3 3 0 MbeD/MobD like DUF2730 PF10805.8 KIK35084.1 - 1.6 8.9 18.6 0.16 12.0 0.8 4.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2730) Trypan_PARP PF05887.11 KIK35085.1 - 0.12 12.3 4.5 0.14 12.1 4.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TP_methylase PF00590.20 KIK35086.1 - 6e-17 62.3 0.0 7.6e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Pkinase_Tyr PF07714.17 KIK35087.1 - 7.3e-08 32.0 0.0 9.1e-08 31.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK35087.1 - 2.8e-06 26.9 0.0 3.4e-06 26.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain ENT PF03735.14 KIK35087.1 - 0.14 12.2 0.3 0.21 11.7 0.3 1.2 1 0 0 1 1 1 0 ENT domain Pkinase_Tyr PF07714.17 KIK35090.1 - 7.9e-37 126.9 0.0 1e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK35090.1 - 1.8e-27 96.4 0.0 2.7e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK35090.1 - 0.0033 16.8 0.2 0.0052 16.2 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK35090.1 - 0.0098 14.7 0.5 0.014 14.2 0.5 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK35090.1 - 0.011 15.6 0.2 0.037 14.0 0.2 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK35090.1 - 0.012 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KIK35090.1 - 0.021 14.4 0.2 0.035 13.7 0.2 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 KIK35091.1 - 1.2e-32 113.3 0.0 1.5e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK35091.1 - 2.5e-28 99.2 0.0 3.4e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK35091.1 - 0.0027 17.7 0.0 0.0047 16.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK35091.1 - 0.019 14.6 0.1 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Haspin_kinase PF12330.8 KIK35091.1 - 0.066 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KIK35091.1 - 0.18 11.1 0.0 1.6 8.0 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Pkinase_Tyr PF07714.17 KIK35093.1 - 4.1e-36 124.6 0.0 5.7e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK35093.1 - 4.8e-29 101.5 0.0 6.7e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK35093.1 - 0.0085 15.5 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIK35093.1 - 0.019 14.3 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KIK35093.1 - 0.069 12.7 0.2 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KIK35093.1 - 0.13 12.1 0.3 8.2 6.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family SAVED PF18145.1 KIK35095.1 - 0.085 12.7 0.1 0.18 11.6 0.0 1.5 1 1 1 2 2 2 0 SMODS-associated and fused to various effectors sensor domain CAML PF14963.6 KIK35096.1 - 7.7 6.5 8.2 9.2 6.3 8.2 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand MIF4G PF02854.19 KIK35098.1 - 4.6e-06 26.4 0.0 1.1e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 MIF4G domain DUF3640 PF12342.8 KIK35098.1 - 0.018 14.8 0.9 0.69 9.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3640) CtsR_C PF17727.1 KIK35098.1 - 0.14 12.3 0.1 0.49 10.6 0.0 2.0 2 0 0 2 2 2 0 CtsR C-terminal dimerization domain MFS_1 PF07690.16 KIK35102.1 - 2.3e-29 102.4 30.7 4.7e-29 101.4 29.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5538 PF17692.1 KIK35106.1 - 0.071 13.2 4.3 0.12 12.4 4.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5538) Integrase_H2C2 PF17921.1 KIK35107.1 - 0.022 14.8 0.5 0.03 14.4 0.5 1.2 1 0 0 1 1 1 0 Integrase zinc binding domain Pkinase PF00069.25 KIK35111.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Dimer_Tnp_hAT PF05699.14 KIK35113.1 - 1.9e-10 40.3 0.0 4.2e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4218 PF13960.6 KIK35116.1 - 0.0016 18.0 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.14 KIK35117.1 - 5.6e-10 38.8 0.0 6.5e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 ANAPC4_WD40 PF12894.7 KIK35119.1 - 1.5e-07 31.6 0.0 0.41 11.0 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KIK35119.1 - 3.6e-05 23.5 1.1 0.00013 21.7 0.5 2.0 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 KIK35119.1 - 0.00021 21.1 0.2 0.23 11.5 0.0 3.4 4 0 0 4 4 4 2 PQQ enzyme repeat PQQ_3 PF13570.6 KIK35119.1 - 0.021 15.3 4.4 0.5 10.9 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain RCC1_2 PF13540.6 KIK35119.1 - 0.068 13.0 1.2 1.6 8.6 0.1 3.0 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.32 KIK35119.1 - 0.11 13.4 10.4 1 10.4 0.1 5.6 7 0 0 7 7 7 0 WD domain, G-beta repeat AF-4 PF05110.13 KIK35120.1 - 0.0082 14.3 4.7 0.0095 14.1 4.7 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein EMG1 PF03587.14 KIK35120.1 - 0.043 13.5 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 EMG1/NEP1 methyltransferase Integrin_beta PF00362.18 KIK35126.1 - 6e-05 22.8 0.0 6.5e-05 22.7 0.0 1.0 1 0 0 1 1 1 1 Integrin beta chain VWA domain VWA_2 PF13519.6 KIK35126.1 - 0.0036 17.9 0.0 0.0044 17.6 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain PD40 PF07676.12 KIK35127.1 - 0.092 12.7 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Nuf2 PF03800.14 KIK35132.1 - 1.6e-15 57.5 0.1 1.5e-10 41.4 0.0 2.8 1 1 1 2 2 2 2 Nuf2 family DHR10 PF18595.1 KIK35132.1 - 1.5e-14 54.0 13.5 1.5e-14 54.0 13.5 3.2 3 1 0 3 3 3 1 Designed helical repeat protein 10 domain APG6_N PF17675.1 KIK35132.1 - 0.034 14.7 25.0 0.27 11.7 5.4 2.8 2 0 0 2 2 2 0 Apg6 coiled-coil region zf-C4H2 PF10146.9 KIK35132.1 - 3.5 7.9 21.0 0.13 12.6 9.4 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein DUF883 PF05957.13 KIK35132.1 - 5.9 7.6 10.9 0.58 10.8 3.2 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF724 PF05266.14 KIK35132.1 - 7.6 6.3 18.5 3.5 7.4 8.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Pkinase_Tyr PF07714.17 KIK35133.1 - 3.8e-06 26.4 0.0 4.3e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK35133.1 - 0.00058 19.3 0.0 0.00073 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Actin PF00022.19 KIK35135.1 - 8.4e-65 218.9 0.0 5.1e-64 216.4 0.0 1.8 1 1 0 1 1 1 1 Actin ECF_trnsprt PF12822.7 KIK35138.1 - 0.00076 19.6 10.3 0.0013 18.9 10.3 1.3 1 0 0 1 1 1 1 ECF transporter, substrate-specific component DUF1686 PF07937.11 KIK35138.1 - 0.027 14.3 5.4 0.034 14.0 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) Sod_Fe_C PF02777.18 KIK35140.1 - 6.2e-33 113.0 0.0 1.1e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KIK35140.1 - 2.7e-31 107.9 3.5 4.4e-31 107.2 1.8 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Carn_acyltransf PF00755.20 KIK35141.1 - 1.8e-199 664.2 0.0 2e-199 664.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Aminotran_1_2 PF00155.21 KIK35142.1 - 4.1e-40 138.1 0.0 4.6e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIK35142.1 - 8.3e-06 24.6 0.0 1.2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KIK35142.1 - 0.00012 21.5 0.0 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KIK35142.1 - 0.003 16.6 0.0 0.0043 16.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KIK35142.1 - 0.017 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Lac_bphage_repr PF06543.12 KIK35142.1 - 0.019 14.9 0.9 0.041 13.9 0.4 1.7 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor SAVED PF18145.1 KIK35142.1 - 0.038 13.8 0.0 0.57 10.0 0.0 2.5 3 0 0 3 3 3 0 SMODS-associated and fused to various effectors sensor domain TPR_10 PF13374.6 KIK35143.1 - 7e-10 38.5 20.0 0.014 15.2 0.3 9.9 9 2 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK35143.1 - 2.6e-07 30.8 13.3 7.9 6.8 0.1 8.7 8 3 2 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK35143.1 - 0.0019 18.1 7.2 6.1 7.1 0.1 7.3 9 1 0 9 9 9 1 Tetratricopeptide repeat AKAP7_NLS PF10469.9 KIK35143.1 - 0.02 14.8 0.0 1.2e+02 2.5 0.0 5.2 1 1 6 7 7 7 0 AKAP7 2'5' RNA ligase-like domain DUF3198 PF11433.8 KIK35143.1 - 0.052 13.4 0.2 2.1e+02 1.9 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF3198) CBP_CCPA PF17040.5 KIK35143.1 - 0.055 14.1 0.1 33 5.1 0.0 3.9 4 0 0 4 4 4 0 Cellulose-complementing protein A SASP PF00269.20 KIK35145.1 - 0.1 12.6 0.2 0.23 11.5 0.2 1.8 1 1 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type TFIIA PF03153.13 KIK35145.1 - 0.69 9.8 10.7 0.86 9.5 10.7 1.2 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Septin PF00735.18 KIK35147.1 - 1.1e-97 326.7 0.8 4.4e-97 324.7 0.8 1.8 1 1 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 KIK35147.1 - 5.4e-07 29.7 0.1 4.1e-06 26.8 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KIK35147.1 - 9.6e-07 28.9 0.1 2.6e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIK35147.1 - 4.8e-06 26.2 1.5 0.00031 20.4 0.1 2.8 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 KIK35147.1 - 0.0003 21.0 0.0 0.00068 19.9 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KIK35147.1 - 0.00034 21.0 0.1 0.001 19.5 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIK35147.1 - 0.0021 18.3 1.8 0.0073 16.6 0.1 2.4 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 KIK35147.1 - 0.0071 16.1 0.3 0.56 9.9 0.1 2.5 1 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.16 KIK35147.1 - 0.0079 15.5 0.1 0.02 14.2 0.0 1.7 2 0 0 2 2 2 1 AIG1 family Ras PF00071.22 KIK35147.1 - 0.009 15.6 0.1 0.031 13.9 0.1 1.9 1 1 0 1 1 1 1 Ras family NB-ARC PF00931.22 KIK35147.1 - 0.0095 15.1 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 KIK35147.1 - 0.01 16.4 0.1 0.028 14.9 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 KIK35147.1 - 0.016 14.8 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KIK35147.1 - 0.047 13.3 0.8 0.13 11.8 0.0 2.1 2 1 1 3 3 3 0 AAA domain AAA_24 PF13479.6 KIK35147.1 - 0.049 13.3 0.2 0.11 12.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KIK35147.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Pox_A32 PF04665.12 KIK35147.1 - 0.065 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_29 PF13555.6 KIK35147.1 - 0.099 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 KIK35147.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain FOXP-CC PF16159.5 KIK35147.1 - 0.13 12.9 0.5 0.37 11.5 0.5 1.8 1 0 0 1 1 1 0 FOXP coiled-coil domain Atg14 PF10186.9 KIK35147.1 - 0.17 10.9 1.6 0.37 9.8 1.6 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Dynamin_N PF00350.23 KIK35147.1 - 0.24 11.5 5.2 7.5 6.6 0.0 3.0 2 1 1 3 3 3 0 Dynamin family AAA PF00004.29 KIK35147.1 - 0.42 11.0 1.9 1 9.8 0.1 2.4 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Casc1_N PF15927.5 KIK35147.1 - 6.1 6.5 12.5 0.29 10.8 6.8 1.7 2 0 0 2 2 1 0 Cancer susceptibility candidate 1 N-terminus SPX PF03105.19 KIK35151.1 - 0.7 9.7 3.3 0.98 9.3 3.3 1.1 1 0 0 1 1 1 0 SPX domain ColG_sub PF18496.1 KIK35153.1 - 0.18 12.0 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Collagenase G catalytic helper subdomain zf-RVT PF13966.6 KIK35155.1 - 7e-05 23.5 0.1 0.00011 22.8 0.1 1.4 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 KIK35156.1 - 3.7e-08 33.2 0.0 3.8e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFIIE_alpha PF02002.17 KIK35156.1 - 0.082 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 TFIIE alpha subunit Exo_endo_phos_2 PF14529.6 KIK35157.1 - 7.5e-05 22.6 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.23 KIK35159.1 - 0.00058 19.8 6.0 0.0012 18.8 2.0 3.0 2 0 0 2 2 2 1 Zinc knuckle EzrA PF06160.12 KIK35161.1 - 0.0056 14.9 0.4 0.0075 14.5 0.4 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Mer2 PF09074.10 KIK35161.1 - 0.026 14.3 2.2 0.042 13.7 2.2 1.2 1 0 0 1 1 1 0 Mer2 CENP-F_leu_zip PF10473.9 KIK35161.1 - 0.028 14.5 0.9 0.054 13.5 0.9 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Moulting_cycle PF04870.16 KIK35161.1 - 0.052 12.8 0.4 0.066 12.5 0.4 1.2 1 0 0 1 1 1 0 Moulting cycle Oscp1 PF10188.9 KIK35161.1 - 0.074 13.2 1.6 0.36 10.9 0.9 2.0 1 1 1 2 2 2 0 Organic solute transport protein 1 SF-assemblin PF06705.11 KIK35161.1 - 0.15 11.4 4.5 0.081 12.3 0.7 2.2 1 1 1 2 2 2 0 SF-assemblin/beta giardin DUF3450 PF11932.8 KIK35161.1 - 0.26 10.5 4.0 0.17 11.2 2.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) PMEI PF04043.15 KIK35161.1 - 0.52 10.6 4.6 1.9 8.9 4.5 1.9 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor CxC5 PF18718.1 KIK35164.1 - 2.3e-37 127.7 6.8 4.4e-37 126.7 6.8 1.5 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 KIK35164.1 - 1.9e-07 31.2 1.3 1.9e-07 31.2 1.3 2.1 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases YdjO PF14169.6 KIK35164.1 - 0.01 15.5 1.6 0.017 14.8 0.1 2.1 2 0 0 2 2 2 0 Cold-inducible protein YdjO DUF4413 PF14372.6 KIK35165.1 - 1.3e-05 25.4 0.0 1.9e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) Dimer_Tnp_hAT PF05699.14 KIK35166.1 - 1.8e-10 40.4 0.1 2.4e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-C2H2 PF00096.26 KIK35169.1 - 5.4e-05 23.4 0.1 0.00013 22.2 0.1 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK35169.1 - 0.00091 19.9 0.1 0.0026 18.5 0.1 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KIK35169.1 - 0.029 14.4 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger UPF0547 PF10571.9 KIK35169.1 - 0.1 12.7 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.6 KIK35169.1 - 0.12 11.8 0.1 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Na_H_Exchanger PF00999.21 KIK35170.1 - 1.1e-08 34.3 0.5 1.7e-08 33.7 0.5 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ASC PF00858.24 KIK35170.1 - 0.086 11.8 0.2 0.14 11.1 0.2 1.2 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel DUF3856 PF12968.7 KIK35170.1 - 0.21 11.7 0.6 3.7 7.6 0.0 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) Plavaka PF18759.1 KIK35174.1 - 2.1e-29 102.8 0.0 4.4e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 Plavaka transposase BicD PF09730.9 KIK35174.1 - 0.062 11.7 0.1 0.096 11.1 0.1 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D zf-3CxxC_2 PF17180.4 KIK35174.1 - 0.79 10.5 3.9 3.3 8.5 3.9 2.1 1 0 0 1 1 1 0 Zinc-binding domain zf-MYND PF01753.18 KIK35176.1 - 3.9e-06 26.8 17.1 8.1e-06 25.8 17.1 1.5 1 1 0 1 1 1 1 MYND finger CRAL_TRIO PF00650.20 KIK35178.1 - 1.7e-27 96.1 0.0 2.7e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK35178.1 - 7.5e-16 58.1 0.1 1.6e-15 57.0 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KIK35178.1 - 0.026 14.7 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KIK35179.1 - 3.9e-29 101.4 0.0 5.9e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK35179.1 - 9.7e-18 64.1 0.9 1.8e-17 63.3 0.9 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Topoisom_bac PF01131.20 KIK35179.1 - 0.19 10.7 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 DNA topoisomerase Abhydrolase_1 PF00561.20 KIK35180.1 - 1.3e-33 116.7 0.0 1.9e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK35180.1 - 2.3e-12 46.7 0.0 1.1e-10 41.2 0.0 2.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIK35180.1 - 8.6e-10 39.6 0.1 1.7e-09 38.6 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KIK35180.1 - 8.9e-05 22.1 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ndr PF03096.14 KIK35180.1 - 0.036 12.8 0.0 0.052 12.2 0.0 1.3 1 0 0 1 1 1 0 Ndr family Peptidase_S28 PF05577.12 KIK35180.1 - 0.093 11.5 0.0 0.23 10.2 0.0 1.6 2 0 0 2 2 2 0 Serine carboxypeptidase S28 Lipoprotein_1 PF00820.19 KIK35180.1 - 0.099 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Borrelia lipoprotein ADH_N PF08240.12 KIK35181.1 - 2.6e-20 72.3 0.3 4.7e-20 71.5 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK35181.1 - 3.1e-15 56.3 0.0 5.5e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KIK35181.1 - 0.0023 17.2 0.1 0.0037 16.6 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KIK35181.1 - 0.035 13.5 0.1 0.061 12.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 KIK35181.1 - 0.074 14.1 0.0 0.13 13.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 KIK35181.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sad1_UNC PF07738.13 KIK35182.1 - 9.8e-25 87.1 0.0 4.8e-11 42.8 0.0 2.8 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal DUF3883 PF13020.6 KIK35183.1 - 0.1 12.6 0.0 1.3 9.1 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3883) Thymidylat_synt PF00303.19 KIK35184.1 - 1e-104 349.4 0.0 1.2e-104 349.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase PPR_2 PF13041.6 KIK35185.1 - 5.6e-09 36.1 0.2 0.093 12.9 0.0 4.8 5 0 0 5 5 5 3 PPR repeat family PPR_3 PF13812.6 KIK35185.1 - 9.3e-09 35.2 0.0 0.00056 19.9 0.0 4.1 3 1 1 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.20 KIK35185.1 - 1.7e-05 24.8 2.2 2.1 8.8 0.1 4.4 5 0 0 5 5 5 2 PPR repeat CagE_TrbE_VirB PF03135.14 KIK35185.1 - 0.033 14.3 0.1 0.082 13.0 0.1 1.6 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system TPR_14 PF13428.6 KIK35185.1 - 0.063 14.1 0.1 1.7e+02 3.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_long PF17177.4 KIK35185.1 - 0.16 11.3 0.1 0.83 9.0 0.0 2.0 1 1 1 2 2 2 0 Pentacotripeptide-repeat region of PRORP Npa1 PF11707.8 KIK35186.1 - 9.9e-98 327.6 0.0 1e-96 324.3 0.0 2.3 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KIK35186.1 - 6e-54 182.7 3.5 1.3e-53 181.6 3.5 1.6 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Creb_binding PF09030.10 KIK35186.1 - 0.0036 18.0 0.0 0.026 15.2 0.0 2.5 2 0 0 2 2 2 1 Creb binding HEAT PF02985.22 KIK35186.1 - 1.3 9.4 3.9 2.5 8.6 0.1 3.8 3 0 0 3 3 3 0 HEAT repeat Abhydrolase_6 PF12697.7 KIK35187.1 - 2.7e-13 51.0 0.0 3.7e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK35187.1 - 0.0012 18.1 0.0 0.0025 17.1 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Zot PF05707.12 KIK35188.1 - 1.3e-05 25.0 0.0 4.6e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.6 KIK35188.1 - 0.00054 20.2 0.0 0.85 9.9 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 KIK35188.1 - 0.014 15.8 0.1 0.24 11.8 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 KIK35188.1 - 0.095 12.8 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_16 PF13191.6 KIK35188.1 - 0.15 12.4 0.0 19 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain PMT PF02366.18 KIK35189.1 - 8.8e-78 261.3 13.7 1.1e-77 261.0 13.7 1.0 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_2 PF13231.6 KIK35189.1 - 5.5e-07 29.9 11.2 6.4e-07 29.7 8.2 2.4 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Bax1-I PF01027.20 KIK35189.1 - 0.49 10.2 10.9 0.98 9.2 10.9 1.4 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF2723 PF11028.8 KIK35189.1 - 4.2 7.3 8.6 0.13 12.2 2.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2723) Kri1 PF05178.12 KIK35190.1 - 2.9e-24 85.6 5.8 2.9e-24 85.6 5.8 6.0 6 1 0 6 6 6 1 KRI1-like family Kri1_C PF12936.7 KIK35190.1 - 3.2e-24 84.9 0.2 3.2e-24 84.9 0.2 4.6 5 0 0 5 5 5 1 KRI1-like family C-terminal Pkinase_Tyr PF07714.17 KIK35191.1 - 0.00058 19.2 0.2 0.00069 19.0 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK35191.1 - 0.044 13.1 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain F-box-like PF12937.7 KIK35192.1 - 6.6e-08 32.3 0.3 6.3e-07 29.2 0.2 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK35192.1 - 0.0058 16.5 0.1 0.049 13.5 0.0 2.6 2 1 0 2 2 2 1 F-box domain Acetyltransf_9 PF13527.7 KIK35193.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK35193.1 - 0.019 15.2 0.0 0.069 13.4 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK35193.1 - 0.16 12.4 0.0 0.51 10.8 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Pantoate_transf PF02548.15 KIK35194.1 - 2.8e-106 354.7 0.1 3.3e-106 354.4 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KIK35194.1 - 1.1e-08 34.9 0.1 2.3e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase PPV_E1_N PF00524.18 KIK35195.1 - 7 7.1 7.0 24 5.3 0.0 3.3 3 0 0 3 3 3 0 E1 Protein, N terminal domain TP_methylase PF00590.20 KIK35196.1 - 4.1e-22 79.2 0.0 5.4e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Evr1_Alr PF04777.13 KIK35197.1 - 2e-26 92.4 0.1 2.8e-26 91.9 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family FixQ PF05545.11 KIK35197.1 - 0.012 15.6 0.5 0.025 14.5 0.4 1.6 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ tRNA-synt_2 PF00152.20 KIK35198.1 - 5.5e-88 295.1 0.0 8.7e-88 294.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIK35198.1 - 1.2e-12 47.6 0.1 3.8e-12 46.0 0.1 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain RGI_lyase PF18370.1 KIK35198.1 - 0.17 12.2 1.2 13 6.2 0.0 2.4 2 0 0 2 2 2 0 Rhamnogalacturonan I lyases beta-sheet domain Toxin_12 PF07740.12 KIK35199.1 - 0.0024 18.5 4.6 0.004 17.8 4.6 1.4 1 0 0 1 1 1 1 Ion channel inhibitory toxin DUF4419 PF14388.6 KIK35200.1 - 2e-89 300.0 0.0 1.4e-88 297.2 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) Glyoxalase_6 PF18029.1 KIK35200.1 - 0.16 12.7 0.0 0.85 10.4 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase-like domain BRX_assoc PF16627.5 KIK35202.1 - 0.56 10.4 14.4 22 5.3 3.4 4.1 1 1 2 3 3 3 0 Unstructured region between BRX_N and BRX domain GRP PF07172.11 KIK35203.1 - 0.024 15.3 0.0 0.13 13.0 0.0 2.0 2 0 0 2 2 2 0 Glycine rich protein family Orf78 PF06024.12 KIK35203.1 - 0.23 11.8 0.6 0.53 10.6 0.2 1.7 1 1 0 2 2 2 0 Orf78 (ac78) GrlR PF16518.5 KIK35204.1 - 0.15 12.0 0.0 0.48 10.4 0.0 1.7 1 1 0 1 1 1 0 T3SS negative regulator,GrlR AT_hook PF02178.19 KIK35206.1 - 0.042 13.7 17.9 0.25 11.4 2.3 2.5 2 0 0 2 2 2 0 AT hook motif FAD_binding_3 PF01494.19 KIK35207.1 - 3.3e-83 279.8 0.0 5.8e-83 279.0 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KIK35207.1 - 2.6e-33 115.4 0.0 4.5e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 KIK35207.1 - 6e-05 21.9 0.3 0.00011 21.0 0.3 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 KIK35207.1 - 6.8e-05 23.0 0.1 0.00022 21.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIK35207.1 - 0.0011 18.2 0.1 0.0019 17.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KIK35207.1 - 0.002 17.5 0.7 0.0034 16.7 0.7 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KIK35207.1 - 0.0063 15.6 0.0 0.0097 15.0 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 KIK35207.1 - 0.0069 16.0 0.1 0.021 14.4 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIK35207.1 - 0.0071 16.9 0.1 0.024 15.2 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK35207.1 - 0.0086 15.2 1.6 0.014 14.5 1.6 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK35207.1 - 0.012 14.9 0.1 0.024 13.9 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK35207.1 - 0.041 12.9 1.2 1.1 8.3 1.1 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KIK35207.1 - 0.1 12.6 0.4 0.22 11.5 0.2 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KIK35207.1 - 0.16 11.3 0.5 0.26 10.6 0.5 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ADIP PF11559.8 KIK35209.1 - 6e-21 75.1 4.8 6e-21 75.1 4.8 3.4 3 1 1 4 4 4 1 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 KIK35209.1 - 0.035 13.4 13.0 0.29 10.4 2.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AIP3 PF03915.13 KIK35209.1 - 0.073 12.2 10.1 0.097 11.8 3.8 2.2 2 0 0 2 2 2 0 Actin interacting protein 3 FAM184 PF15665.5 KIK35209.1 - 1.2 8.9 19.4 6.5 6.5 10.4 3.1 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B MnmE_helical PF12631.7 KIK35209.1 - 1.9 8.6 5.7 4.5 7.4 5.6 1.7 1 1 0 1 1 1 0 MnmE helical domain UCH PF00443.29 KIK35211.1 - 4.9e-65 219.6 0.0 8.7e-65 218.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIK35211.1 - 2.5e-20 73.3 0.0 4.6e-18 65.9 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-HC5HC2H_2 PF13832.6 KIK35212.1 - 3.8e-20 72.1 1.1 3.8e-20 72.1 1.1 4.4 4 1 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KIK35212.1 - 3.7e-15 55.9 1.4 3.7e-15 55.9 1.4 5.2 4 2 1 5 5 5 1 PHD-like zinc-binding domain PHD PF00628.29 KIK35212.1 - 1.7e-14 53.4 57.1 1.9e-08 34.1 8.1 6.9 7 0 0 7 7 7 4 PHD-finger BAH PF01426.18 KIK35212.1 - 4.9e-14 52.2 0.1 3.7e-13 49.4 0.0 2.2 2 0 0 2 2 2 1 BAH domain PHD_2 PF13831.6 KIK35212.1 - 0.00025 20.5 34.3 0.0045 16.5 6.4 5.6 5 0 0 5 5 5 3 PHD-finger ELM2 PF01448.24 KIK35212.1 - 0.0034 18.1 0.0 0.011 16.5 0.0 1.9 1 0 0 1 1 1 1 ELM2 domain GATA PF00320.27 KIK35212.1 - 0.0091 15.6 4.9 0.0091 15.6 4.9 3.7 3 0 0 3 3 3 1 GATA zinc finger Myb_DNA-binding PF00249.31 KIK35212.1 - 0.019 15.1 0.2 0.078 13.2 0.0 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain AT_hook PF02178.19 KIK35212.1 - 0.17 11.9 4.9 0.58 10.2 4.9 2.0 1 0 0 1 1 1 0 AT hook motif C1_2 PF03107.16 KIK35212.1 - 1.5 9.2 39.2 0.21 11.9 0.3 7.0 7 0 0 7 7 7 0 C1 domain UL42 PF17638.2 KIK35213.1 - 0.16 11.9 1.7 0.18 11.8 1.7 1.1 1 0 0 1 1 1 0 HCMV UL42 GST_N_3 PF13417.6 KIK35215.1 - 1.5e-10 41.4 0.0 3.1e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK35215.1 - 4.2e-09 36.6 0.0 1.2e-08 35.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK35215.1 - 8.7e-05 22.5 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK35215.1 - 0.0009 19.4 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIK35215.1 - 0.0033 17.6 0.0 0.0049 17.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KIK35215.1 - 0.0048 17.2 0.0 0.056 13.8 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain SHR-BD PF06650.12 KIK35216.1 - 0.037 13.4 0.0 0.058 12.8 0.0 1.4 1 1 0 1 1 1 0 SHR-binding domain of vacuolar-sorting associated protein 13 FxsA PF04186.13 KIK35216.1 - 0.16 12.1 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein GST_N_3 PF13417.6 KIK35217.1 - 6.7e-10 39.3 0.0 2.1e-09 37.7 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK35217.1 - 4e-08 33.4 0.0 1e-07 32.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK35217.1 - 0.0034 17.6 0.0 0.0067 16.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK35217.1 - 0.0049 17.0 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK35217.1 - 0.039 14.0 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIK35218.1 - 6.6e-09 36.1 0.1 2e-08 34.5 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK35218.1 - 5e-07 29.9 0.0 1.2e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK35218.1 - 0.00038 20.6 0.0 0.00075 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK35218.1 - 0.01 16.0 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK35218.1 - 0.028 14.4 0.0 0.081 13.0 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ion_trans PF00520.31 KIK35220.1 - 2.8e-19 69.3 18.9 2.8e-19 69.3 18.9 1.3 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 KIK35220.1 - 1.6e-11 44.0 4.7 1.6e-11 44.0 4.7 2.6 2 2 0 2 2 2 1 Ion channel Lig_chan PF00060.26 KIK35220.1 - 0.0021 17.9 0.3 0.0021 17.9 0.3 1.9 2 0 0 2 2 2 1 Ligand-gated ion channel DUF962 PF06127.11 KIK35220.1 - 5.5 7.1 7.5 7.6 6.7 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF962) DUF2614 PF11023.8 KIK35220.1 - 8.1 6.6 8.1 1.9 8.6 3.1 2.3 1 1 1 2 2 2 0 Zinc-ribbon containing domain Ribonuclease_3 PF00636.26 KIK35221.1 - 1.4e-41 141.4 0.0 2.4e-21 76.3 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KIK35221.1 - 1.8e-25 89.6 0.1 2.6e-09 37.3 0.0 4.4 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KIK35221.1 - 3.9e-21 75.0 0.0 2e-20 72.7 0.0 2.2 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 KIK35221.1 - 2.1e-15 57.1 0.0 1.2e-14 54.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK35221.1 - 4e-15 56.0 0.0 7.6e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIK35221.1 - 1.1e-12 48.3 0.0 2e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit GTP_CH_N PF12471.8 KIK35222.1 - 4.7e-90 300.5 0.0 7.1e-90 300.0 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KIK35222.1 - 5.3e-14 52.1 0.0 8.5e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II CHAT PF12770.7 KIK35223.1 - 2.2e-05 24.0 0.0 2.3e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 CHAT domain Plavaka PF18759.1 KIK35226.1 - 2.6e-24 86.1 1.3 4.6e-24 85.2 0.1 2.0 3 0 0 3 3 3 1 Plavaka transposase DUF3305 PF11749.8 KIK35228.1 - 0.098 12.8 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3305) Pkinase PF00069.25 KIK35229.1 - 6.5e-22 78.2 0.0 7.4e-22 78.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK35229.1 - 5.3e-20 71.8 0.0 6.5e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK35229.1 - 0.0078 16.2 0.1 0.017 15.1 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KIK35229.1 - 0.031 13.6 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KIK35229.1 - 0.056 13.0 0.0 0.09 12.3 0.0 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 KIK35229.1 - 0.057 13.0 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family TIM21 PF08294.11 KIK35230.1 - 1.1e-06 28.6 0.0 1.7e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 TIM21 RNA_pol_Rpb1_1 PF04997.12 KIK35231.1 - 1.8e-14 53.8 0.7 1.9e-14 53.8 0.7 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 Chal_sti_synt_N PF00195.19 KIK35232.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.0 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain PROCT PF08084.11 KIK35233.1 - 1.5e-38 131.5 0.0 1.7e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 PROCT (NUC072) domain JAKMIP_CC3 PF16034.5 KIK35234.1 - 0.017 15.1 0.1 0.028 14.4 0.1 1.3 1 0 0 1 1 1 0 JAKMIP CC3 domain ET PF01684.16 KIK35234.1 - 0.062 13.6 0.3 0.16 12.3 0.1 1.7 2 0 0 2 2 2 0 ET module DUF2779 PF11074.8 KIK35235.1 - 0.051 14.0 0.0 0.055 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) Plavaka PF18759.1 KIK35236.1 - 2e-35 122.6 0.0 2.7e-33 115.6 0.0 2.2 1 1 1 2 2 2 2 Plavaka transposase DDE_Tnp_4 PF13359.6 KIK35239.1 - 0.00027 20.6 0.2 0.011 15.4 0.1 2.1 2 0 0 2 2 2 2 DDE superfamily endonuclease Plant_tran PF04827.14 KIK35239.1 - 0.006 16.2 0.0 0.0072 15.9 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein zf-C2HC_2 PF13913.6 KIK35241.1 - 2.2e-05 24.2 4.9 4e-05 23.4 4.9 1.5 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-Di19 PF05605.12 KIK35241.1 - 0.015 15.6 1.2 0.021 15.1 0.7 1.6 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Prim_Zn_Ribbon PF08273.12 KIK35241.1 - 0.018 15.3 0.3 0.04 14.2 0.3 1.6 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase zf-C2H2_4 PF13894.6 KIK35241.1 - 0.028 15.2 3.5 0.028 15.2 3.5 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ACC PF17848.1 KIK35241.1 - 0.05 13.7 0.1 0.05 13.7 0.1 1.9 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain zf-C2H2 PF00096.26 KIK35241.1 - 0.066 13.7 1.3 0.066 13.7 1.3 2.4 3 1 0 3 3 3 0 Zinc finger, C2H2 type Zn_Tnp_IS1595 PF12760.7 KIK35241.1 - 0.069 13.1 5.4 0.12 12.4 1.9 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.6 KIK35241.1 - 0.1 12.4 0.5 0.1 12.4 0.5 1.7 1 1 1 2 2 2 0 zinc-ribbon domain HpaB PF03241.13 KIK35247.1 - 0.2 10.7 0.0 0.26 10.3 0.0 1.1 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal FHA PF00498.26 KIK35248.1 - 3.6e-16 59.3 0.0 7.3e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KIK35248.1 - 2e-11 43.4 8.3 3.4e-11 42.7 8.3 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KIK35248.1 - 2.1e-09 37.6 8.8 3.1e-09 37.0 8.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIK35248.1 - 9.6e-06 25.4 8.8 1.5e-05 24.7 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK35248.1 - 1.6e-05 24.7 9.1 2.5e-05 24.0 9.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KIK35248.1 - 1.6e-05 24.9 1.5 2.6e-05 24.2 1.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KIK35248.1 - 6.1e-05 23.2 5.8 0.00012 22.3 5.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KIK35248.1 - 0.00051 19.9 7.2 0.00089 19.2 7.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Yop-YscD_cpl PF16697.5 KIK35248.1 - 0.0032 17.8 0.0 0.0058 16.9 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_3 PF13920.6 KIK35248.1 - 0.0087 15.9 6.0 0.013 15.3 6.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KIK35248.1 - 0.011 15.6 4.3 0.02 14.8 4.3 1.3 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 KIK35248.1 - 0.037 14.1 6.9 0.066 13.2 6.9 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KIK35248.1 - 0.067 13.4 1.6 0.067 13.4 1.6 1.6 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KIK35248.1 - 0.22 11.4 7.0 0.4 10.6 7.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KIK35248.1 - 0.22 11.2 5.0 0.39 10.4 5.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Tmemb_170 PF10190.9 KIK35250.1 - 0.083 13.3 0.0 0.083 13.3 0.0 1.1 1 0 0 1 1 1 0 Putative transmembrane protein 170 Peroxidase_2 PF01328.17 KIK35251.1 - 2.4e-45 155.4 0.0 3.1e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Yip1 PF04893.17 KIK35252.1 - 5.4e-06 26.2 27.4 8.5e-06 25.6 27.4 1.3 1 1 0 1 1 1 1 Yip1 domain NCE101 PF11654.8 KIK35253.1 - 0.039 13.7 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Non-classical export protein 1 DUF543 PF04418.12 KIK35254.1 - 6.2e-29 99.8 0.3 7e-29 99.6 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) BRO1 PF03097.18 KIK35255.1 - 3.4e-119 398.1 1.2 4.8e-119 397.6 0.3 1.7 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KIK35255.1 - 4e-56 190.5 6.5 6e-56 189.9 6.5 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV AIM5 PF17050.5 KIK35256.1 - 0.00043 21.0 0.2 0.0006 20.6 0.2 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 AA_permease_2 PF13520.6 KIK35257.1 - 1.7e-47 162.2 51.1 2.2e-47 161.9 51.1 1.1 1 0 0 1 1 1 1 Amino acid permease Putative_PNPOx PF01243.20 KIK35257.1 - 0.085 13.1 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase KcnmB2_inactiv PF09303.10 KIK35258.1 - 0.19 11.5 0.1 0.33 10.8 0.1 1.4 1 0 0 1 1 1 0 KCNMB2, ball and chain domain F-box-like PF12937.7 KIK35261.1 - 1.2e-05 25.1 0.1 1.6e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 F-box-like Pkinase_Tyr PF07714.17 KIK35262.1 - 1.1e-29 103.6 0.0 1.4e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK35262.1 - 7.4e-25 87.8 0.0 9.5e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK35262.1 - 0.0033 17.4 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KIK35264.1 - 9.6e-39 133.2 0.0 1.2e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK35264.1 - 1.3e-29 103.4 0.0 1.8e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK35264.1 - 0.029 13.2 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KIK35264.1 - 0.047 13.6 0.1 0.078 12.9 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KIK35264.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIK35264.1 - 0.23 11.0 0.1 0.48 10.0 0.0 1.5 2 0 0 2 2 2 0 RIO1 family CorA PF01544.18 KIK35265.1 - 1.7e-31 109.7 8.2 8.7e-27 94.2 6.3 3.0 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein DIOX_N PF14226.6 KIK35266.1 - 4.1e-13 50.1 0.0 8.5e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK35266.1 - 3.6e-12 46.7 0.0 1e-11 45.2 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.22 KIK35267.1 - 1.7e-67 228.2 0.0 2e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ABC_tran PF00005.27 KIK35268.1 - 3.6e-20 72.9 0.0 7.9e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KIK35268.1 - 2e-13 50.2 25.5 2.9e-13 49.7 25.5 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 KIK35268.1 - 2.1e-06 27.8 0.2 0.0016 18.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 KIK35268.1 - 0.015 16.0 0.0 0.036 14.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) AAA_23 PF13476.6 KIK35268.1 - 0.018 15.6 0.0 0.029 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KIK35268.1 - 0.064 12.7 0.0 0.48 9.8 0.0 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KIK35268.1 - 0.16 11.9 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase DUF3825 PF12873.7 KIK35269.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) RNA_pol_Rpb1_R PF05001.13 KIK35270.1 - 0.14 12.5 1.2 0.34 11.4 1.2 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb1 C-terminal repeat Bac_rhodopsin PF01036.18 KIK35271.1 - 0.02 14.5 2.0 0.026 14.1 2.0 1.3 1 0 0 1 1 1 0 Bacteriorhodopsin-like protein AMP-binding PF00501.28 KIK35274.1 - 2.6e-68 230.6 0.0 3.7e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KIK35274.1 - 9e-63 211.8 0.0 3.5e-62 209.9 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.25 KIK35274.1 - 1.7e-11 44.3 0.0 4.8e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.20 KIK35274.1 - 8.4e-09 34.6 0.0 2.5e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 Condensation domain Epimerase PF01370.21 KIK35274.1 - 7.6e-06 25.6 0.0 2e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 KIK35274.1 - 0.00038 21.4 0.0 0.0012 19.8 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 KIK35274.1 - 0.00065 18.8 0.0 0.0031 16.6 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F-box-like PF12937.7 KIK35275.1 - 3.8e-07 29.9 1.6 1.2e-06 28.3 1.6 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK35275.1 - 0.00027 20.8 0.4 0.00064 19.5 0.4 1.6 1 0 0 1 1 1 1 F-box domain DNA_methylase PF00145.17 KIK35276.1 - 4.3e-42 144.7 0.0 5.9e-40 137.6 0.0 2.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 KIK35276.1 - 5e-16 58.7 0.1 1.2e-08 34.8 0.0 2.7 2 0 0 2 2 2 2 BAH domain Cons_hypoth95 PF03602.15 KIK35276.1 - 0.0093 15.6 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 DNMT1-RFD PF12047.8 KIK35276.1 - 0.042 13.9 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain zf-CSL PF05207.13 KIK35277.1 - 6.4e-13 48.2 1.6 8.6e-13 47.8 1.6 1.2 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 KIK35277.1 - 2.3e-11 43.7 0.0 3.4e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Sel1 PF08238.12 KIK35278.1 - 1.8e-45 152.3 19.5 1.2e-08 35.3 0.0 7.4 7 0 0 7 7 7 7 Sel1 repeat HNH_repeat PF18780.1 KIK35278.1 - 0.099 12.5 2.5 1.2 9.0 0.0 2.7 3 0 0 3 3 3 0 Homing endonuclease repeat ANAPC3 PF12895.7 KIK35278.1 - 0.24 11.6 2.5 2 8.7 0.6 3.2 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Exo84_C PF16528.5 KIK35279.1 - 2.1e-37 129.0 0.0 7.3e-37 127.2 0.0 2.0 1 1 0 1 1 1 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KIK35279.1 - 9.6e-18 64.1 1.0 3.2e-17 62.4 1.0 1.9 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 KIK35279.1 - 3.3e-07 30.5 1.9 3.3e-07 30.5 1.9 2.3 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec3-PIP2_bind PF15277.6 KIK35279.1 - 0.0046 17.1 0.0 0.0093 16.1 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH PH_13 PF16652.5 KIK35279.1 - 0.039 13.8 0.3 0.1 12.4 0.3 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain zf-C2H2 PF00096.26 KIK35281.1 - 4.9 7.8 7.6 6.8 7.4 4.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type WD40 PF00400.32 KIK35283.1 - 3.2e-20 72.1 3.5 5.1e-05 24.0 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35283.1 - 8.8e-07 29.1 0.0 0.0011 19.2 0.0 4.0 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 KIK35283.1 - 0.0036 17.1 0.0 0.28 10.9 0.0 2.6 1 1 1 2 2 2 1 TUP1-like enhancer of split Nup160 PF11715.8 KIK35283.1 - 0.021 13.5 0.3 0.24 10.0 0.0 2.6 3 1 0 3 3 3 0 Nucleoporin Nup120/160 Glycos_transf_2 PF00535.26 KIK35286.1 - 1.6e-28 99.7 0.0 2e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIK35286.1 - 2.2e-12 47.4 0.0 2.6e-11 43.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KIK35286.1 - 0.00077 19.0 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 HATPase_c PF02518.26 KIK35288.1 - 2.6e-22 79.5 0.0 7.6e-22 77.9 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KIK35288.1 - 4.8e-18 65.4 0.1 4.3e-10 39.8 0.0 2.9 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.25 KIK35288.1 - 6e-07 29.4 0.1 8.2e-06 25.8 0.0 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 KIK35288.1 - 0.026 14.3 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ISN1 PF06437.11 KIK35288.1 - 0.1 11.5 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase ANP PF00212.18 KIK35288.1 - 0.11 12.7 0.3 0.37 11.0 0.3 1.9 1 0 0 1 1 1 0 Atrial natriuretic peptide IDO PF01231.18 KIK35290.1 - 2e-08 33.4 0.0 2.5e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1971 PF09313.11 KIK35290.1 - 0.24 11.4 0.9 0.61 10.1 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1971) WD40 PF00400.32 KIK35293.1 - 7.1e-29 99.5 16.1 4.7e-07 30.4 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35293.1 - 1.2e-12 47.9 0.0 0.011 16.0 0.0 4.8 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WW PF00397.26 KIK35293.1 - 4.6e-08 33.0 3.2 3.2e-06 27.1 0.5 3.1 2 0 0 2 2 2 2 WW domain Nup160 PF11715.8 KIK35293.1 - 0.00018 20.3 0.4 0.01 14.5 0.1 2.8 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK35293.1 - 0.0043 16.1 0.0 10 5.0 0.0 3.9 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KIK35295.1 - 7.3e-13 48.8 7.3 8.6e-08 32.7 0.2 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat WW PF00397.26 KIK35295.1 - 1.1e-06 28.6 0.5 1.1e-06 28.6 0.5 2.3 3 0 0 3 3 3 1 WW domain ANAPC4_WD40 PF12894.7 KIK35295.1 - 1.4e-05 25.3 0.1 0.0039 17.5 0.1 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK35295.1 - 0.034 13.1 0.0 2.5 7.0 0.0 2.3 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Plavaka PF18759.1 KIK35297.1 - 1.5e-132 441.7 0.0 1.9e-132 441.4 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase WD40 PF00400.32 KIK35299.1 - 8.8e-20 70.7 10.2 5.6e-08 33.3 0.2 4.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35299.1 - 1.6e-07 31.5 0.0 0.011 16.0 0.0 3.5 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK35299.1 - 0.0011 18.9 0.0 0.066 13.1 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Kelch_2 PF07646.15 KIK35299.1 - 0.02 14.8 0.1 6.3 6.9 0.0 3.2 2 1 0 2 2 2 0 Kelch motif Ge1_WD40 PF16529.5 KIK35299.1 - 0.032 13.2 0.0 0.25 10.2 0.0 2.3 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK35299.1 - 0.084 11.5 0.0 0.13 10.9 0.0 1.5 1 1 0 1 1 1 0 Nucleoporin Nup120/160 KDZ PF18758.1 KIK35300.1 - 1.9e-65 220.6 0.8 3.4e-65 219.8 0.8 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase zf-CCHC PF00098.23 KIK35301.1 - 8.3 6.7 6.2 36 4.7 2.3 2.4 2 0 0 2 2 2 0 Zinc knuckle EcoEI_R_C PF08463.10 KIK35303.1 - 0.03 14.4 0.0 4.7 7.3 0.0 2.0 1 1 1 2 2 2 0 EcoEI R protein C-terminal HTH_20 PF12840.7 KIK35303.1 - 0.083 13.0 0.0 0.46 10.6 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain RVT_1 PF00078.27 KIK35304.1 - 0.075 12.5 0.0 0.075 12.5 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KIK35305.1 - 1.8e-10 40.8 0.0 2.1e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KIK35305.1 - 0.089 13.1 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase rve PF00665.26 KIK35306.1 - 2.5e-06 27.7 0.0 8.2e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Phage_term_smal PF05944.12 KIK35306.1 - 0.094 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Phage small terminase subunit CdiI_N PF18228.1 KIK35308.1 - 0.015 15.1 0.2 0.069 13.0 0.1 2.2 2 0 0 2 2 2 0 CdiI N-terminal domain Exo_endo_phos PF03372.23 KIK35309.1 - 5.6e-09 35.9 0.0 7.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ABC_ATPase PF09818.9 KIK35311.1 - 4.7 5.9 7.9 6 5.5 7.9 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Sugar_tr PF00083.24 KIK35312.1 - 8.2e-80 268.8 24.1 9.5e-80 268.7 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK35312.1 - 8e-31 107.2 37.2 2.7e-23 82.5 15.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily EMP70 PF02990.16 KIK35312.1 - 0.014 14.1 0.9 0.014 14.1 0.9 3.1 2 1 1 3 3 3 0 Endomembrane protein 70 Phage_holin_3_2 PF04550.12 KIK35312.1 - 0.071 13.7 1.3 0.19 12.3 1.3 1.7 1 0 0 1 1 1 0 Phage holin family 2 Alpha-amylase PF00128.24 KIK35313.1 - 2.7e-24 86.4 0.0 7.3e-24 84.9 0.0 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KIK35313.1 - 0.0034 15.6 0.2 6.2 4.9 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 WD40 PF00400.32 KIK35315.1 - 6.6e-22 77.4 1.9 1.6e-09 38.2 0.0 3.3 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35315.1 - 3.5e-06 27.2 0.0 0.024 14.9 0.0 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KIK35315.1 - 7.2e-06 26.0 0.0 5e-05 23.3 0.0 2.4 2 1 0 2 2 2 1 NACHT domain Ge1_WD40 PF16529.5 KIK35315.1 - 3.4e-05 23.0 0.0 0.2 10.6 0.0 2.3 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 KIK35315.1 - 0.00038 20.9 0.1 0.0025 18.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KIK35315.1 - 0.015 14.5 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.17 KIK35315.1 - 0.03 13.4 0.0 0.071 12.2 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.29 KIK35315.1 - 0.04 14.3 0.0 0.15 12.5 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PD40 PF07676.12 KIK35315.1 - 0.047 13.7 4.3 3.9 7.5 0.0 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat RNA_helicase PF00910.22 KIK35315.1 - 0.12 12.8 0.1 0.47 10.9 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Integrase_H2C2 PF17921.1 KIK35317.1 - 2.6e-08 33.9 0.8 3.3e-08 33.5 0.8 1.1 1 0 0 1 1 1 1 Integrase zinc binding domain KDZ PF18758.1 KIK35321.1 - 0.022 14.4 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK35322.1 - 1.6e-44 150.5 0.0 3.1e-44 149.5 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK35322.1 - 8.7e-07 29.0 0.0 1.7e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK35322.1 - 0.0072 16.2 0.0 0.0072 16.2 0.0 2.2 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases Transformer PF06495.11 KIK35324.1 - 0.046 13.8 1.8 0.05 13.7 1.8 1.0 1 0 0 1 1 1 0 Fruit fly transformer protein DUF1028 PF06267.12 KIK35324.1 - 0.094 12.5 0.0 0.094 12.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF1028) Asp PF00026.23 KIK35325.1 - 5.4e-46 157.5 12.8 2.5e-45 155.3 12.8 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK35325.1 - 2.8e-08 34.2 5.8 0.00015 22.1 0.1 3.3 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK35325.1 - 0.06 14.0 3.8 1.3 9.7 0.5 2.8 2 1 0 2 2 2 0 Aspartyl protease Trp_halogenase PF04820.14 KIK35326.1 - 3.1e-30 105.4 0.0 1e-14 54.3 0.0 2.3 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KIK35326.1 - 1.1e-13 51.2 0.0 1.4e-12 47.5 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KIK35326.1 - 1.3e-06 28.5 0.2 6.6e-06 26.3 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK35326.1 - 2.8e-05 23.9 0.0 0.00056 19.6 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KIK35326.1 - 0.00015 21.2 0.2 0.00026 20.5 0.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK35326.1 - 0.00074 18.8 0.0 0.0021 17.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK35326.1 - 0.001 17.8 0.0 0.0018 17.1 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein TrbI PF03743.14 KIK35326.1 - 0.002 18.0 0.0 0.0049 16.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein FAD_binding_2 PF00890.24 KIK35326.1 - 0.0051 15.9 0.0 0.0085 15.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KIK35326.1 - 0.0054 15.9 0.0 0.0079 15.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KIK35326.1 - 0.015 15.8 0.0 0.041 14.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK35326.1 - 0.024 13.9 0.0 0.067 12.4 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 KIK35326.1 - 0.15 11.0 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KIK35326.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase LCAT PF02450.15 KIK35327.1 - 3e-86 290.1 0.2 1.9e-78 264.3 0.5 2.0 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 KIK35327.1 - 0.02 14.4 0.1 0.035 13.6 0.1 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) KDZ PF18758.1 KIK35328.1 - 4.6e-28 98.3 0.1 7.9e-28 97.6 0.1 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK35328.1 - 0.0013 18.8 0.0 0.003 17.7 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases PHINT_rpt PF14882.6 KIK35328.1 - 0.095 13.0 0.0 0.29 11.4 0.0 1.8 2 0 0 2 2 2 0 Phage-integrase repeat unit KDZ PF18758.1 KIK35329.1 - 1.2e-46 159.1 1.4 1.5e-46 158.8 1.4 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase GvpG PF05120.12 KIK35329.1 - 0.013 15.5 0.3 0.022 14.8 0.3 1.3 1 0 0 1 1 1 0 Gas vesicle protein G Arnt_C PF18583.1 KIK35332.1 - 0.018 14.7 0.3 0.037 13.6 0.2 1.5 1 1 1 2 2 2 0 Aminoarabinose transferase C-terminal domain RNase_J_C PF17770.1 KIK35332.1 - 0.11 13.6 0.8 0.16 13.0 0.1 1.7 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain MKRN1_C PF15815.5 KIK35334.1 - 0.037 14.4 0.1 0.042 14.2 0.1 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase makorin-1, C-terminal DUF1542 PF07564.11 KIK35335.1 - 0.042 13.9 0.3 0.095 12.8 0.3 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) ArgoMid PF16487.5 KIK35335.1 - 0.048 13.9 0.4 4.2 7.7 0.1 2.9 2 1 1 3 3 3 0 Mid domain of argonaute KxDL PF10241.9 KIK35335.1 - 0.14 12.5 1.4 0.25 11.7 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein KDZ PF18758.1 KIK35337.1 - 2.2e-45 155.0 4.1 4e-45 154.1 4.1 1.4 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase WD40 PF00400.32 KIK35344.1 - 2e-41 139.2 10.7 5.8e-07 30.1 2.4 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35344.1 - 2.4e-21 75.8 0.8 8e-06 26.1 0.0 6.2 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK35344.1 - 6.4e-08 32.7 0.3 2.7e-06 27.4 0.0 3.0 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK35344.1 - 4.4e-05 22.6 0.0 0.019 14.0 0.0 3.3 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK35344.1 - 0.00027 19.8 0.2 0.99 8.0 0.3 4.0 2 1 2 4 4 4 1 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 KIK35344.1 - 0.002 17.5 0.2 0.062 12.6 0.0 2.5 3 0 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus PD40 PF07676.12 KIK35344.1 - 0.0039 17.1 0.0 29 4.8 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK35344.1 - 0.0078 15.6 0.2 0.26 10.6 0.0 3.2 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.14 KIK35344.1 - 0.034 13.2 0.7 3.1 6.7 0.1 2.2 1 1 1 2 2 2 0 Coatomer WD associated region WD40 PF00400.32 KIK35345.1 - 2.8e-39 132.4 11.5 4.9e-07 30.3 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35345.1 - 5e-20 71.6 2.1 0.00018 21.7 0.0 6.1 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK35345.1 - 4.8e-08 32.1 3.1 0.00035 19.4 0.2 3.9 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK35345.1 - 8e-08 31.6 0.0 0.3 10.0 0.0 4.5 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK35345.1 - 6.8e-06 25.6 0.9 0.00062 19.2 0.0 3.3 2 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 KIK35345.1 - 0.00056 19.9 0.1 0.0085 16.0 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KIK35345.1 - 0.0041 15.7 0.0 0.016 13.7 0.0 1.9 1 1 0 2 2 2 1 Cytochrome D1 heme domain SGL PF08450.12 KIK35345.1 - 0.0095 15.5 0.1 0.039 13.5 0.1 2.0 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region WD40_like PF17005.5 KIK35345.1 - 0.014 14.7 0.0 4.8 6.4 0.0 3.2 3 1 1 4 4 4 0 WD40-like domain CBM_48 PF02922.18 KIK35345.1 - 0.037 14.4 0.5 12 6.4 0.0 3.4 3 0 0 3 3 3 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) PD40 PF07676.12 KIK35345.1 - 0.088 12.8 0.9 1e+02 3.0 0.0 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 KIK35345.1 - 0.11 11.3 0.5 19 3.9 0.0 3.4 1 1 3 4 4 4 0 Nup133 N terminal like F-box-like PF12937.7 KIK35346.1 - 0.00059 19.7 0.1 0.0016 18.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like PCO_ADO PF07847.12 KIK35347.1 - 0.12 11.8 0.0 0.12 11.8 0.0 1.0 1 0 0 1 1 1 0 PCO_ADO WD40 PF00400.32 KIK35348.1 - 4.3e-41 138.1 17.1 8.9e-07 29.5 0.5 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35348.1 - 3.1e-19 69.0 4.6 5.3e-05 23.4 0.1 6.3 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK35348.1 - 2.8e-06 26.3 0.7 0.69 8.5 0.0 3.8 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK35348.1 - 1.2e-05 24.4 0.0 0.014 14.4 0.0 3.5 3 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK35348.1 - 3.8e-05 23.2 0.7 0.0013 18.1 0.0 3.3 3 2 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK35348.1 - 0.012 15.0 0.0 2.8 7.2 0.0 3.7 3 2 1 4 4 4 0 WD40-like domain BBS2_Mid PF14783.6 KIK35348.1 - 0.02 14.9 0.2 6 7.0 0.0 3.6 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.12 KIK35348.1 - 0.053 13.5 0.3 15 5.7 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 KIK35348.1 - 0.057 12.5 0.2 0.14 11.2 0.1 1.5 1 1 0 2 2 2 0 Coatomer WD associated region Cytochrom_D1 PF02239.16 KIK35348.1 - 0.077 11.5 0.1 1.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 KIK35348.1 - 0.13 12.7 0.1 30 5.3 0.0 4.2 4 1 1 5 5 5 0 PQQ-like domain PALB2_WD40 PF16756.5 KIK35348.1 - 0.59 9.0 4.5 7.3 5.4 0.3 3.1 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain WD40 PF00400.32 KIK35353.1 - 1.5e-32 111.1 22.6 3e-11 43.7 0.4 5.1 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35353.1 - 7e-13 48.7 0.0 0.0061 16.8 0.0 3.3 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK35353.1 - 1e-09 37.9 0.0 0.012 14.7 0.0 3.1 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK35353.1 - 6.1e-06 26.0 2.9 0.73 9.8 0.1 4.4 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 KIK35353.1 - 0.00037 20.3 4.2 0.00075 19.3 4.2 1.6 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain PQQ_3 PF13570.6 KIK35353.1 - 0.00073 19.9 4.9 1.6 9.4 0.1 3.5 3 0 0 3 3 3 2 PQQ-like domain eIF2A PF08662.11 KIK35353.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KIK35353.1 - 0.021 13.2 0.0 5.5 5.2 0.0 2.9 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40_3 PF15911.5 KIK35353.1 - 0.028 14.4 0.2 19 5.4 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Cuticle_4 PF15955.5 KIK35353.1 - 0.046 14.4 0.2 28 5.5 0.0 3.1 3 0 0 3 3 3 0 Cuticle protein DUF4596 PF15363.6 KIK35353.1 - 0.2 11.9 14.6 1.5 9.1 0.3 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF4596) GspH PF12019.8 KIK35353.1 - 1.1 9.7 6.3 27 5.2 3.3 3.4 1 1 1 2 2 2 0 Type II transport protein GspH TPR_2 PF07719.17 KIK35355.1 - 1.6 9.0 3.8 57 4.2 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.32 KIK35356.1 - 4.2e-11 43.2 0.2 9.8e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35356.1 - 0.00028 21.1 0.0 0.05 13.9 0.0 1.4 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain NTNH_C PF08470.10 KIK35356.1 - 0.032 14.1 0.0 0.038 13.9 0.0 1.1 1 0 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal Nup160 PF11715.8 KIK35356.1 - 0.06 12.0 0.0 0.067 11.8 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 WD40 PF00400.32 KIK35357.1 - 1.2e-12 48.1 0.0 6.8e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35357.1 - 0.0042 17.3 0.0 1.9 8.9 0.0 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PMT_4TMC PF16192.5 KIK35360.1 - 2.9e-31 108.6 0.3 3.7e-31 108.3 0.3 1.2 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KIK35360.1 - 3.5e-16 59.6 0.1 4.8e-16 59.1 0.1 1.2 1 0 0 1 1 1 1 MIR domain WD40 PF00400.32 KIK35362.1 - 3.4e-26 91.0 2.7 1.7e-09 38.1 0.1 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat AAA_16 PF13191.6 KIK35362.1 - 3e-09 37.5 0.1 1.2e-08 35.5 0.1 2.1 1 0 0 1 1 1 1 AAA ATPase domain ANAPC4_WD40 PF12894.7 KIK35362.1 - 5.6e-09 36.2 0.0 0.0028 17.9 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK35362.1 - 3e-07 29.7 0.2 0.017 14.1 0.0 3.0 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KIK35362.1 - 6.7e-06 26.1 0.0 1.7e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.12 KIK35362.1 - 1.9e-05 24.5 1.6 2.3 8.3 0.0 3.6 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat AAA PF00004.29 KIK35362.1 - 0.00018 21.9 0.0 0.00078 19.9 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KIK35362.1 - 0.00033 20.7 0.0 0.0012 18.8 0.0 1.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 KIK35362.1 - 0.0011 18.1 0.0 0.0019 17.4 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 APS_kinase PF01583.20 KIK35362.1 - 0.0039 17.1 0.0 0.008 16.1 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase Gmad1 PF10647.9 KIK35362.1 - 0.028 14.2 2.2 0.045 13.5 2.2 1.3 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain RNA_helicase PF00910.22 KIK35362.1 - 0.031 14.7 0.0 0.12 12.7 0.0 2.1 1 0 0 1 1 1 0 RNA helicase eIF2A PF08662.11 KIK35362.1 - 0.048 13.5 0.0 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A AAA_22 PF13401.6 KIK35362.1 - 0.05 13.9 0.0 0.27 11.5 0.0 2.3 2 1 0 2 2 1 0 AAA domain Nup160 PF11715.8 KIK35362.1 - 0.08 11.6 0.0 2.1 6.9 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 NB-ARC PF00931.22 KIK35362.1 - 0.13 11.4 0.0 0.52 9.4 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain DUF3313 PF11769.8 KIK35362.1 - 0.15 11.8 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) HET PF06985.11 KIK35363.1 - 1.3e-09 38.5 4.0 6.4e-08 33.1 0.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Pkinase_Tyr PF07714.17 KIK35364.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase 4HBT PF03061.22 KIK35365.1 - 3.3e-07 30.6 0.1 0.0061 16.9 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily DUF89 PF01937.19 KIK35366.1 - 3.2e-89 299.3 0.0 3.7e-89 299.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF4461 PF14688.6 KIK35366.1 - 0.015 15.1 0.1 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) Peptidase_C65 PF10275.9 KIK35367.1 - 4.3e-56 190.1 0.0 5.1e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 KIK35367.1 - 8.5e-06 26.3 0.0 0.0019 18.7 0.0 2.2 2 0 0 2 2 2 2 OTU-like cysteine protease BolA PF01722.18 KIK35369.1 - 2.7e-14 53.2 0.2 6e-14 52.1 0.2 1.5 1 1 0 1 1 1 1 BolA-like protein CHAT PF12770.7 KIK35370.1 - 6.9e-08 32.2 0.0 7.1e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 CHAT domain NAD_binding_4 PF07993.12 KIK35372.1 - 1.8e-29 102.7 0.0 2.5e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIK35372.1 - 1.1e-27 96.7 0.0 2.2e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KIK35372.1 - 1.2e-05 24.9 0.0 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIK35372.1 - 0.037 14.4 0.0 0.18 12.2 0.0 2.1 1 1 0 1 1 1 0 Phosphopantetheine attachment site NAD_binding_10 PF13460.6 KIK35372.1 - 0.097 12.5 0.0 0.3 11.0 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H-binding MLANA PF14991.6 KIK35373.1 - 0.044 14.1 0.0 0.087 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A MTCP1 PF08991.10 KIK35374.1 - 1.8e-15 56.9 8.1 2.3e-13 50.1 8.1 2.0 1 1 0 1 1 1 1 Mature-T-Cell Proliferation I type DHC_N2 PF08393.13 KIK35374.1 - 0.0067 15.6 0.0 0.0075 15.4 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 BRK PF07533.16 KIK35374.1 - 0.11 12.2 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 BRK domain CX9C PF16860.5 KIK35374.1 - 0.3 11.1 4.7 0.17 11.9 2.5 1.6 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF4092 PF13322.6 KIK35375.1 - 0.045 13.6 0.1 0.049 13.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4092) DUF1510 PF07423.11 KIK35376.1 - 0.031 14.4 3.0 0.66 10.2 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1510) PAT1 PF09770.9 KIK35376.1 - 0.89 7.7 14.3 1.2 7.3 14.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.13 KIK35376.1 - 1.2 9.8 18.3 3.2 8.4 18.3 1.9 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pneumo_att_G PF05539.11 KIK35376.1 - 4.6 6.7 12.7 7.9 6.0 12.7 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G GREB1 PF15782.5 KIK35376.1 - 7.9 3.4 9.0 10 3.1 9.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pkinase_fungal PF17667.1 KIK35380.1 - 4.6e-16 58.6 0.2 5.7e-14 51.7 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIK35380.1 - 0.0012 18.3 0.0 0.0016 17.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain AAA PF00004.29 KIK35382.1 - 2.4e-48 163.9 0.0 1.5e-41 141.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIK35382.1 - 2.4e-09 36.8 0.0 8.1e-09 35.1 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KIK35382.1 - 1.2e-07 32.3 1.0 1.6e-05 25.3 0.0 3.8 3 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 KIK35382.1 - 3.2e-06 27.0 0.0 6.8e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KIK35382.1 - 6e-05 23.2 0.0 0.00015 21.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KIK35382.1 - 0.002 18.4 1.6 0.16 12.2 0.2 3.9 4 1 0 4 4 3 1 AAA domain AAA_5 PF07728.14 KIK35382.1 - 0.0046 17.0 0.0 0.029 14.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KIK35382.1 - 0.0072 16.5 0.1 0.038 14.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIK35382.1 - 0.018 14.6 0.0 0.26 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KIK35382.1 - 0.052 13.8 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KIK35382.1 - 0.055 12.9 0.1 0.35 10.3 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 KIK35382.1 - 0.061 12.7 0.1 0.15 11.5 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KIK35382.1 - 0.064 13.8 0.0 0.22 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KIK35382.1 - 0.069 12.9 0.0 0.29 10.9 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 KIK35382.1 - 0.086 12.5 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KIK35382.1 - 0.12 12.2 0.0 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK35382.1 - 0.14 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 KIK35382.1 - 0.17 11.0 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_11 PF13086.6 KIK35382.1 - 0.25 11.1 9.6 1 9.1 0.0 3.6 4 0 0 4 4 4 0 AAA domain Sugar_tr PF00083.24 KIK35386.1 - 2.5e-93 313.4 25.5 3.1e-93 313.1 25.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK35386.1 - 1.1e-21 77.2 55.5 4e-19 68.8 25.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SRP54 PF00448.22 KIK35390.1 - 2e-15 56.9 1.9 2.6e-08 33.8 0.1 2.1 1 1 1 2 2 2 2 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 KIK35390.1 - 0.0042 17.4 0.0 0.0065 16.8 0.0 1.4 1 0 0 1 1 1 1 RNA helicase CbiA PF01656.23 KIK35390.1 - 0.018 15.1 0.1 0.039 14.0 0.1 1.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KIK35390.1 - 0.16 11.7 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Plavaka PF18759.1 KIK35392.1 - 1.8e-11 43.8 0.0 2.7e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK35393.1 - 6.1e-15 55.3 0.0 1.1e-14 54.5 0.0 1.3 1 1 0 1 1 1 1 Plavaka transposase DUF5358 PF17311.2 KIK35395.1 - 0.06 13.4 0.1 0.093 12.7 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5358) WD40 PF00400.32 KIK35396.1 - 5.3e-09 36.6 0.5 2.6e-05 24.9 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF1582 PF07621.11 KIK35396.1 - 0.012 15.5 1.1 0.024 14.5 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1582) PQQ_3 PF13570.6 KIK35396.1 - 0.083 13.4 1.9 18 6.0 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain ANAPC4_WD40 PF12894.7 KIK35396.1 - 0.11 12.8 0.0 11 6.4 0.0 3.4 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain UXS1_N PF11803.8 KIK35396.1 - 0.19 12.1 0.1 0.38 11.1 0.1 1.4 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal PQQ PF01011.21 KIK35396.1 - 0.52 10.3 2.3 2 8.5 0.2 2.9 3 0 0 3 3 3 0 PQQ enzyme repeat KOW PF00467.29 KIK35397.1 - 2.9e-14 52.4 15.7 0.0014 18.5 0.1 7.4 7 0 0 7 7 7 6 KOW motif DUF150_C PF17384.2 KIK35397.1 - 0.037 14.2 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 RimP C-terminal SH3 domain Pkinase_fungal PF17667.1 KIK35398.1 - 1.6e-14 53.5 0.0 7.8e-11 41.4 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase NolV PF06635.12 KIK35398.1 - 0.039 13.3 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein NolV Pkinase_fungal PF17667.1 KIK35399.1 - 2.6e-19 69.3 0.1 2.8e-19 69.2 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK35399.1 - 0.00033 20.1 0.0 0.00038 19.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK35399.1 - 0.00066 19.7 0.0 0.00094 19.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK35399.1 - 0.025 14.2 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Regulator_TrmB PF11495.8 KIK35400.1 - 0.2 10.8 0.3 0.27 10.4 0.3 1.2 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB SPATA24 PF15175.6 KIK35400.1 - 0.23 11.4 0.1 0.49 10.3 0.1 1.4 1 1 0 1 1 1 0 Spermatogenesis-associated protein 24 DUF3797 PF12677.7 KIK35400.1 - 0.28 11.1 0.1 0.28 11.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) Transposase_21 PF02992.14 KIK35401.1 - 2.6e-08 33.4 0.0 3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 Plavaka PF18759.1 KIK35401.1 - 0.0059 15.9 0.9 0.0064 15.8 0.9 1.1 1 0 0 1 1 1 1 Plavaka transposase DUF4218 PF13960.6 KIK35402.1 - 0.00011 21.8 0.1 0.00016 21.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) RNase_H PF00075.24 KIK35404.1 - 1.5e-05 25.2 0.0 2e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 RNase H DUF3328 PF11807.8 KIK35406.1 - 2.9e-13 50.1 3.7 3.5e-13 49.8 3.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Abhydrolase_1 PF00561.20 KIK35407.1 - 3.2e-14 53.2 0.0 5.4e-14 52.4 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK35407.1 - 1.2e-11 44.3 0.2 6.4e-11 42.0 0.2 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIK35407.1 - 2.4e-07 31.6 0.0 3.1e-07 31.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 KIK35407.1 - 0.037 13.9 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Rav1p_C PF12234.8 KIK35411.1 - 0.1 11.0 0.0 0.1 11.0 0.0 1.0 1 0 0 1 1 1 0 RAVE protein 1 C terminal DUF4229 PF14012.6 KIK35415.1 - 3.2 7.9 8.7 48 4.1 8.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4229) VPS9 PF02204.18 KIK35417.1 - 9.7e-18 64.3 0.0 1.6e-16 60.4 0.0 2.3 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Nop14 PF04147.12 KIK35417.1 - 0.18 10.0 2.8 0.28 9.3 2.8 1.2 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 KIK35417.1 - 0.48 10.3 5.7 0.11 12.4 0.7 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC45 PF02724.14 KIK35417.1 - 1.5 7.1 5.2 2.2 6.5 5.2 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KIK35417.1 - 2.3 7.5 7.5 3.5 6.9 7.5 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KIK35417.1 - 4.6 5.2 9.0 7.7 4.5 9.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 KIK35417.1 - 7.2 7.1 11.5 17 5.8 11.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4795 PF16043.5 KIK35419.1 - 0.017 14.7 0.2 0.035 13.7 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Ribonuc_L-PSP PF01042.21 KIK35421.1 - 4e-34 117.2 0.0 4.4e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Pkinase_fungal PF17667.1 KIK35423.1 - 1.1e-18 67.2 0.0 1.4e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK35423.1 - 0.0029 17.0 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK35424.1 - 2.5e-13 49.6 0.0 4.9e-13 48.6 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Plavaka PF18759.1 KIK35426.1 - 9.3e-24 84.2 0.1 1.3e-14 54.1 0.0 3.4 3 0 0 3 3 3 3 Plavaka transposase zf-C2HC_2 PF13913.6 KIK35426.1 - 0.014 15.3 2.0 0.045 13.7 2.0 2.0 1 0 0 1 1 1 0 zinc-finger of a C2HC-type gag_pre-integrs PF13976.6 KIK35428.1 - 3.3e-06 26.8 0.1 4.3e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 KIK35430.1 - 0.00023 20.8 0.2 0.00038 20.1 0.2 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type RUN PF02759.19 KIK35430.1 - 0.037 14.0 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 RUN domain DNA_pack_N PF02500.15 KIK35431.1 - 0.088 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus FOXP-CC PF16159.5 KIK35432.1 - 0.17 12.6 0.7 0.26 11.9 0.7 1.2 1 0 0 1 1 1 0 FOXP coiled-coil domain UL42 PF17638.2 KIK35432.1 - 0.19 11.7 9.6 0.34 10.9 9.6 1.4 1 0 0 1 1 1 0 HCMV UL42 VWA PF00092.28 KIK35433.1 - 4.6e-09 36.8 0.0 8.1e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIK35433.1 - 1.1e-07 32.4 0.0 2.5e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Integrin_beta PF00362.18 KIK35433.1 - 0.056 13.1 0.0 0.39 10.3 0.0 2.1 1 1 1 2 2 2 0 Integrin beta chain VWA domain SRP_SPB PF02978.19 KIK35433.1 - 0.082 13.5 0.0 0.18 12.5 0.0 1.5 1 0 0 1 1 1 0 Signal peptide binding domain WD40 PF00400.32 KIK35434.1 - 5.4e-30 103.0 30.2 6.2e-07 30.0 0.1 7.6 8 0 0 8 8 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35434.1 - 2.8e-17 62.8 5.6 0.0011 19.2 0.1 5.4 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK35434.1 - 1.9e-08 33.6 0.4 0.16 10.9 0.0 4.2 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK35434.1 - 8.5e-07 28.0 8.4 0.16 10.6 0.0 5.3 2 2 5 7 7 7 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK35434.1 - 2.6e-05 23.7 0.0 0.052 12.9 0.0 2.2 2 0 0 2 2 2 2 WD40-like domain eIF2A PF08662.11 KIK35434.1 - 0.0002 21.3 0.7 0.037 13.9 0.3 2.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KIK35434.1 - 0.0075 14.8 1.9 0.2 10.2 0.0 2.4 2 1 0 2 2 2 1 Cytochrome D1 heme domain DUF5570 PF17731.1 KIK35434.1 - 0.0089 16.1 1.3 4.3 7.4 0.0 4.2 3 2 1 4 4 4 1 Family of unknown function (DUF5570) Nbas_N PF15492.6 KIK35434.1 - 0.011 15.0 1.4 10 5.3 0.2 3.8 2 2 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.14 KIK35434.1 - 0.016 14.3 0.1 0.25 10.4 0.0 2.3 2 1 0 2 2 2 0 Coatomer WD associated region PD40 PF07676.12 KIK35434.1 - 0.046 13.7 0.1 17 5.5 0.0 3.8 4 0 0 4 4 3 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 KIK35434.1 - 0.07 12.7 4.1 1.5 8.3 4.1 2.4 1 1 0 1 1 1 0 PQQ-like domain PQQ PF01011.21 KIK35434.1 - 0.089 12.8 0.1 8.1 6.6 0.0 3.8 4 0 0 4 4 4 0 PQQ enzyme repeat GPI-anchored PF10342.9 KIK35439.1 - 0.0015 19.2 0.1 0.0034 18.1 0.1 1.6 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cellulase PF00150.18 KIK35441.1 - 1.9e-13 50.5 0.4 6.2e-13 48.8 0.4 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 KIK35441.1 - 0.00081 19.1 0.0 0.36 10.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF4038) HEAT_2 PF13646.6 KIK35442.1 - 0.0035 17.7 3.9 0.1 13.0 1.3 3.0 2 2 0 2 2 2 2 HEAT repeats Pyr_redox_3 PF13738.6 KIK35443.1 - 1.2e-21 77.2 0.0 3.2e-20 72.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KIK35443.1 - 2.1e-19 69.4 0.1 6.3e-17 61.2 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KIK35443.1 - 1.9e-16 60.1 0.0 1.3e-13 50.9 0.0 2.6 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK35443.1 - 6.7e-14 51.8 0.0 1.2e-10 41.1 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KIK35443.1 - 6.5e-08 31.7 0.1 6.8e-05 21.7 0.0 2.5 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 KIK35443.1 - 8.3e-08 32.4 0.8 0.00018 21.6 0.0 3.3 3 1 1 4 4 4 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KIK35443.1 - 3.7e-07 30.3 0.0 2.1e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIK35443.1 - 1.7e-06 28.5 1.1 0.017 15.7 0.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KIK35443.1 - 2.5e-06 27.6 0.3 0.0005 20.1 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KIK35443.1 - 2.9e-06 26.8 0.9 3.6e-06 26.5 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KIK35443.1 - 3.3e-05 23.7 3.4 0.0029 17.3 0.2 3.5 3 1 1 4 4 4 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KIK35443.1 - 0.00013 22.4 0.0 0.051 14.0 0.1 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding GIDA PF01134.22 KIK35443.1 - 0.0023 17.1 3.3 0.21 10.6 0.0 3.1 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KIK35443.1 - 0.0043 16.4 0.2 0.0078 15.6 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KIK35443.1 - 0.0065 15.9 0.0 1.6 8.0 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KIK35443.1 - 0.0084 15.2 0.4 0.0084 15.2 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KIK35443.1 - 0.01 14.9 1.3 0.15 11.1 0.1 2.9 3 1 0 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.17 KIK35443.1 - 0.014 14.7 0.0 0.1 11.8 0.0 2.1 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 KIK35443.1 - 0.022 15.0 0.2 0.56 10.5 0.0 2.5 3 0 0 3 3 2 0 TrkA-N domain AlaDh_PNT_C PF01262.21 KIK35443.1 - 0.071 12.4 0.1 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF4147 PF13660.6 KIK35443.1 - 0.14 11.6 0.0 0.81 9.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) ThiF PF00899.21 KIK35443.1 - 0.16 11.3 0.0 3.7 6.8 0.0 2.1 2 0 0 2 2 2 0 ThiF family Trp_halogenase PF04820.14 KIK35443.1 - 0.58 8.9 5.8 0.16 10.8 0.4 2.3 3 0 0 3 3 3 0 Tryptophan halogenase Plavaka PF18759.1 KIK35446.1 - 0.02 14.1 4.4 0.023 13.9 4.4 1.0 1 0 0 1 1 1 0 Plavaka transposase Pkinase_fungal PF17667.1 KIK35455.1 - 0.069 11.9 0.0 0.089 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DDE_1 PF03184.19 KIK35456.1 - 0.00043 20.0 0.0 0.00043 20.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease SIR2_2 PF13289.6 KIK35457.1 - 0.037 14.2 0.0 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 SIR2-like domain Kelch_2 PF07646.15 KIK35459.1 - 0.077 13.0 0.1 0.89 9.6 0.0 2.1 2 0 0 2 2 2 0 Kelch motif RVP_2 PF08284.11 KIK35460.1 - 2e-06 27.6 0.0 2.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 KIK35460.1 - 0.049 13.2 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 Ty3 transposon peptidase Asp_protease_2 PF13650.6 KIK35460.1 - 0.05 14.2 0.0 0.068 13.8 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Pkinase_fungal PF17667.1 KIK35462.1 - 1.6e-18 66.7 0.0 2.3e-17 62.9 0.0 1.9 1 1 0 1 1 1 1 Fungal protein kinase Plavaka PF18759.1 KIK35463.1 - 2.7e-60 204.3 2.0 2.3e-46 158.5 0.1 2.3 1 1 1 2 2 2 2 Plavaka transposase Myb_DNA-bind_3 PF12776.7 KIK35465.1 - 0.06 14.3 0.0 0.073 14.1 0.0 1.1 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain YniB PF14002.6 KIK35468.1 - 0.077 12.8 1.3 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 YniB-like protein DUF3007 PF11460.8 KIK35468.1 - 0.91 9.8 3.2 1.9 8.8 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) S1-P1_nuclease PF02265.16 KIK35469.1 - 6.9e-47 160.4 0.0 7.4e-43 147.2 0.0 2.9 2 1 0 2 2 2 2 S1/P1 Nuclease Methyltransf_16 PF10294.9 KIK35470.1 - 5.3e-05 23.0 0.0 0.36 10.5 0.0 2.3 1 1 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 KIK35470.1 - 0.00056 19.8 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK35470.1 - 0.0046 16.8 0.0 2.4 7.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KIK35470.1 - 0.047 14.4 0.0 9.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Myticin-prepro PF10690.9 KIK35473.1 - 0.0094 16.2 2.7 0.013 15.7 2.7 1.3 1 1 0 1 1 1 1 Myticin pre-proprotein from the mussel Serglycin PF04360.12 KIK35473.1 - 0.097 12.6 0.1 0.1 12.5 0.1 1.1 1 0 0 1 1 1 0 Serglycin Pyr_redox_3 PF13738.6 KIK35475.1 - 1.6e-21 76.8 0.0 3.2e-20 72.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KIK35475.1 - 9.5e-18 63.9 0.1 9.9e-15 53.9 0.0 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KIK35475.1 - 5.5e-17 61.9 0.0 2.7e-14 53.1 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK35475.1 - 1.7e-13 50.4 0.0 7.3e-11 41.8 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KIK35475.1 - 9.3e-08 32.2 0.0 6.8e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIK35475.1 - 9e-07 29.4 1.2 0.012 16.2 0.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIK35475.1 - 1.6e-06 27.6 0.7 2.5e-06 27.0 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KIK35475.1 - 1.8e-06 28.1 0.8 0.00028 20.9 0.0 3.4 3 1 1 4 4 4 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KIK35475.1 - 2.4e-06 27.6 0.1 0.00035 20.7 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KIK35475.1 - 5.2e-06 25.4 1.2 4.9e-05 22.2 0.0 2.6 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 KIK35475.1 - 7.1e-06 25.8 1.9 0.0019 17.8 0.1 3.6 3 1 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KIK35475.1 - 0.00011 22.5 0.0 0.051 14.0 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KIK35475.1 - 0.0013 17.9 0.6 0.005 16.0 0.1 2.1 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 KIK35475.1 - 0.0031 16.6 0.6 0.065 12.3 0.1 2.6 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KIK35475.1 - 0.0031 16.9 0.1 0.0048 16.3 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIK35475.1 - 0.0085 15.3 0.0 0.074 12.3 0.0 2.1 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.19 KIK35475.1 - 0.0087 15.4 0.0 2.7 7.3 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KIK35475.1 - 0.012 14.7 1.9 0.15 11.2 0.0 3.0 3 1 1 4 4 4 0 Glucose inhibited division protein A TrkA_N PF02254.18 KIK35475.1 - 0.014 15.6 0.0 0.43 10.9 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain AlaDh_PNT_C PF01262.21 KIK35475.1 - 0.043 13.1 0.1 0.2 10.9 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Peptidase_M17_N PF02789.17 KIK35475.1 - 0.065 13.1 0.6 8.9 6.2 0.1 2.8 2 1 1 3 3 3 0 Cytosol aminopeptidase family, N-terminal domain DUF4147 PF13660.6 KIK35475.1 - 0.072 12.6 0.0 0.52 9.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) ApbA PF02558.16 KIK35475.1 - 0.074 12.7 0.0 6.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 KIK35475.1 - 0.084 12.2 0.0 2.6 7.3 0.0 2.1 2 0 0 2 2 2 0 ThiF family Trp_halogenase PF04820.14 KIK35475.1 - 0.19 10.5 2.8 0.12 11.2 0.4 1.8 2 0 0 2 2 2 0 Tryptophan halogenase RTA1 PF04479.13 KIK35477.1 - 1.2e-60 204.7 4.8 1.2e-60 204.7 4.8 1.4 2 0 0 2 2 2 1 RTA1 like protein IncE PF17627.2 KIK35477.1 - 5.1 7.1 7.1 1.2 9.2 3.8 1.7 2 1 0 2 2 2 0 Inclusion membrane protein E CHAT PF12770.7 KIK35478.1 - 2.5e-31 109.2 0.0 4.6e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK35478.1 - 3e-09 36.5 5.2 0.0013 18.5 0.1 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK35478.1 - 0.00037 20.2 4.1 1 9.3 0.1 5.9 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK35478.1 - 0.021 14.9 5.8 19 5.7 0.1 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK35478.1 - 0.11 12.7 0.7 35 5.0 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK35478.1 - 0.15 11.8 0.6 44 3.9 0.0 3.9 3 0 0 3 3 3 0 TPR repeat TPR_7 PF13176.6 KIK35478.1 - 4.7 7.5 10.2 3.9 7.7 0.0 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat RTA1 PF04479.13 KIK35481.1 - 5.5e-57 192.7 3.9 5.5e-57 192.7 3.9 1.7 2 0 0 2 2 2 1 RTA1 like protein Ferric_reduct PF01794.19 KIK35482.1 - 7.6e-21 74.5 7.1 1.6e-20 73.5 7.1 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KIK35482.1 - 1.7e-11 44.5 0.0 2.6e-10 40.7 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KIK35482.1 - 9.1e-08 32.2 0.0 1.9e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ctr PF04145.15 KIK35483.1 - 1.9e-23 83.7 2.7 4e-23 82.7 2.7 1.5 1 1 0 1 1 1 1 Ctr copper transporter family ApoO PF09769.9 KIK35484.1 - 2.1e-22 79.4 0.2 5.9e-22 78.0 0.0 1.7 2 0 0 2 2 2 1 Apolipoprotein O DUF1451 PF07295.11 KIK35484.1 - 0.098 12.7 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain OrfB_Zn_ribbon PF07282.11 KIK35485.1 - 0.019 14.8 3.0 0.024 14.5 3.0 1.2 1 1 0 1 1 1 0 Putative transposase DNA-binding domain WD40 PF00400.32 KIK35486.1 - 3.5e-20 72.0 1.3 1.7e-08 35.0 0.2 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.8 KIK35486.1 - 2.8e-05 23.0 0.3 0.0086 14.8 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KIK35486.1 - 3.5e-05 24.0 0.2 0.24 11.7 0.1 2.4 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK35486.1 - 0.00046 19.6 0.0 0.65 9.3 0.0 2.4 3 0 0 3 3 3 2 WD40-like domain DUF4287 PF14117.6 KIK35486.1 - 0.15 12.2 0.1 0.36 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) WD40 PF00400.32 KIK35487.1 - 1.3e-27 95.5 8.6 2.4e-09 37.7 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35487.1 - 2.6e-08 34.0 0.5 0.14 12.5 0.0 3.9 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK35487.1 - 0.0017 17.4 0.0 0.65 8.9 0.0 2.3 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK35487.1 - 0.0035 16.1 0.2 0.04 12.6 0.0 2.2 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KIK35487.1 - 0.031 12.8 0.1 0.26 9.8 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain HCV_NS5a_C PF12941.7 KIK35487.1 - 0.078 12.8 0.3 0.078 12.8 0.3 2.1 2 0 0 2 2 2 0 HCV NS5a protein C-terminal region PD40 PF07676.12 KIK35487.1 - 0.22 11.5 1.8 20 5.2 0.1 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat HSP20 PF00011.21 KIK35490.1 - 5.6e-23 81.0 0.1 9.1e-23 80.4 0.1 1.4 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIK35490.1 - 2.2e-10 40.0 0.0 3.8e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF4097 PF13349.6 KIK35490.1 - 0.0034 16.8 0.2 0.0043 16.4 0.2 1.1 1 0 0 1 1 1 1 Putative adhesin CS PF04969.16 KIK35490.1 - 0.011 16.8 0.1 0.016 16.2 0.1 1.4 1 1 0 1 1 1 0 CS domain CAP_N PF01213.19 KIK35491.1 - 1.4e-82 277.7 14.7 2e-82 277.2 0.0 2.1 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KIK35491.1 - 2.6e-25 88.9 3.4 3.7e-25 88.4 3.4 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KIK35491.1 - 0.047 13.4 2.1 0.079 12.7 2.1 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor C Plavaka PF18759.1 KIK35492.1 - 3.5e-34 118.5 0.0 6.4e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase XPB_DRD PF18458.1 KIK35492.1 - 0.12 12.3 0.0 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 Xeroderma pigmentosum group B helicase damage recognition domain Trns_repr_metal PF02583.17 KIK35494.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor Dimer_Tnp_hAT PF05699.14 KIK35495.1 - 0.0033 17.2 0.4 0.0048 16.6 0.4 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-RING_2 PF13639.6 KIK35496.1 - 1.2e-11 44.8 4.6 2.1e-11 44.0 4.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KIK35496.1 - 1.4e-07 31.1 1.7 1.4e-07 31.1 1.7 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KIK35496.1 - 1.5e-06 27.9 3.9 2.7e-06 27.1 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KIK35496.1 - 1.1e-05 25.4 1.2 2e-05 24.6 1.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KIK35496.1 - 4.7e-05 23.6 4.4 0.00014 22.0 4.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KIK35496.1 - 5e-05 23.0 2.7 9e-05 22.2 2.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 KIK35496.1 - 0.00017 21.4 2.1 0.00031 20.6 2.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK35496.1 - 0.00027 20.8 1.7 0.00049 20.0 1.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KIK35496.1 - 0.0044 16.8 1.2 0.0079 16.0 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK35496.1 - 0.0069 16.4 3.4 0.34 11.0 0.9 2.5 2 0 0 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.8 KIK35496.1 - 0.0086 16.2 2.9 0.039 14.1 2.9 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain Prok-RING_4 PF14447.6 KIK35496.1 - 0.0097 15.7 5.0 0.081 12.8 5.5 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 RINGv PF12906.7 KIK35496.1 - 0.1 12.7 2.4 0.21 11.8 2.4 1.5 1 0 0 1 1 1 0 RING-variant domain UBZ_FAAP20 PF15750.5 KIK35496.1 - 0.18 11.8 0.8 7.2 6.6 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Abhydrolase_1 PF00561.20 KIK35497.1 - 3.3e-11 43.3 0.1 9.8e-11 41.8 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK35497.1 - 0.0013 19.4 0.0 0.0016 19.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family HSP9_HSP12 PF04119.12 KIK35498.1 - 1.2e-20 73.6 11.9 1.2e-20 73.6 11.9 1.7 2 0 0 2 2 2 1 Heat shock protein 9/12 COPR5 PF15340.6 KIK35498.1 - 0.18 12.5 3.2 0.21 12.2 3.2 1.1 1 0 0 1 1 1 0 Cooperator of PRMT5 family Josephin PF02099.17 KIK35499.1 - 1.6e-49 168.1 0.2 3.3e-49 167.1 0.2 1.5 1 0 0 1 1 1 1 Josephin UIM PF02809.20 KIK35499.1 - 0.0048 16.7 12.1 1.2 9.2 0.4 4.1 3 0 0 3 3 3 3 Ubiquitin interaction motif 3-PAP PF12578.8 KIK35499.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Myotubularin-associated protein PDZ_5 PF17817.1 KIK35499.1 - 0.075 13.3 0.9 2.9 8.2 0.1 2.9 2 0 0 2 2 2 0 PDZ domain ATG27 PF09451.10 KIK35500.1 - 6e-65 219.7 0.0 7e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 KIK35500.1 - 0.0012 18.0 0.0 0.0019 17.4 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor QSregVF_b PF12843.7 KIK35502.1 - 0.00014 21.7 0.0 0.1 12.5 0.0 2.7 2 1 0 2 2 2 2 Putative quorum-sensing-regulated virulence factor HMG_box PF00505.19 KIK35503.1 - 1.1e-10 41.7 0.1 2e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK35503.1 - 0.0012 19.4 0.0 0.0031 18.0 0.0 1.7 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 KIK35503.1 - 0.078 12.9 0.7 0.17 11.9 0.5 1.5 1 1 0 1 1 1 0 HMG (high mobility group) box 5 Myosin_N PF02736.19 KIK35504.1 - 0.091 12.6 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain WW PF00397.26 KIK35509.1 - 0.0076 16.3 0.1 0.021 14.9 0.1 1.7 1 0 0 1 1 1 1 WW domain LapA_dom PF06305.11 KIK35509.1 - 2.1 8.2 9.1 0.81 9.5 3.4 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Gpr1_Fun34_YaaH PF01184.19 KIK35510.1 - 3.3e-47 160.8 18.2 4.1e-47 160.5 18.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Mpv17_PMP22 PF04117.12 KIK35512.1 - 1.2e-20 73.4 0.1 2.1e-20 72.7 0.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family zf-MYND PF01753.18 KIK35513.1 - 3.7e-06 26.9 12.4 7.1e-06 26.0 12.4 1.5 1 0 0 1 1 1 1 MYND finger CHAT PF12770.7 KIK35516.1 - 3.7e-30 105.3 0.1 7.9e-30 104.3 0.1 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK35516.1 - 4.6e-11 42.2 11.4 0.035 14.0 0.0 7.9 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK35516.1 - 1.7e-08 34.6 10.1 1.1 9.5 0.4 8.1 4 2 5 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 KIK35516.1 - 3.5e-07 29.8 4.9 2.8 8.3 0.3 8.8 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK35516.1 - 1.6e-05 24.5 7.0 2.1 8.3 0.4 8.0 9 1 0 9 9 9 1 Tetratricopeptide repeat Sel1 PF08238.12 KIK35516.1 - 0.00016 22.2 1.6 3.2 8.6 0.0 5.1 4 1 0 4 4 4 2 Sel1 repeat TPR_14 PF13428.6 KIK35516.1 - 0.0003 21.3 22.4 10 7.2 0.0 10.3 11 2 2 13 13 12 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK35516.1 - 0.00042 20.3 0.0 17 5.9 0.1 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK35516.1 - 0.0013 18.6 13.6 3.9 7.7 0.7 7.2 6 2 1 7 7 6 2 Tetratricopeptide repeat MIT PF04212.18 KIK35516.1 - 0.004 17.2 0.0 21 5.3 0.0 5.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 KIK35516.1 - 0.012 15.3 0.2 1.5 8.6 0.1 3.6 2 0 0 2 2 2 0 TPR repeat Dehydratase_SU PF02287.15 KIK35516.1 - 0.07 13.2 0.0 4.3 7.4 0.0 2.7 2 0 0 2 2 2 0 Dehydratase small subunit Exonuc_VII_S PF02609.16 KIK35516.1 - 0.083 13.0 0.6 1.4 9.0 0.0 3.2 4 0 0 4 4 4 0 Exonuclease VII small subunit Ost4 PF10215.9 KIK35516.1 - 0.2 11.5 0.1 6.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Oligosaccaryltransferase F-box-like PF12937.7 KIK35518.1 - 2.5e-06 27.3 0.8 6.1e-06 26.0 0.8 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK35518.1 - 0.023 14.6 0.0 0.1 12.5 0.0 2.1 1 0 0 1 1 1 0 F-box domain DFF40 PF09230.10 KIK35522.1 - 0.044 13.4 0.0 0.05 13.2 0.0 1.1 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa Glyco_transf_20 PF00982.21 KIK35524.1 - 9.8e-138 459.8 0.0 1.3e-137 459.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KIK35524.1 - 7e-21 74.4 0.0 1.1e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 KIK35524.1 - 0.067 12.9 0.1 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Starch synthase catalytic domain DUF1087 PF06465.13 KIK35524.1 - 0.18 11.8 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) WD40 PF00400.32 KIK35525.1 - 1.2e-23 82.9 14.1 8.7e-07 29.5 0.2 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35525.1 - 1.8e-08 34.5 0.6 0.0006 20.1 0.1 3.4 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK35525.1 - 0.036 12.7 0.0 0.73 8.4 0.0 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Pkinase PF00069.25 KIK35528.1 - 7e-74 248.5 0.0 1.3e-73 247.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK35528.1 - 1.1e-33 116.7 0.0 1.7e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK35528.1 - 1.5e-05 24.0 0.0 5.8e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KIK35528.1 - 1.8e-05 24.2 0.0 3.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK35528.1 - 0.00049 19.5 0.0 0.0016 17.9 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FERM_N PF09379.10 KIK35528.1 - 0.057 13.4 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 FERM N-terminal domain APH PF01636.23 KIK35528.1 - 0.058 13.3 0.0 0.28 11.1 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KIK35528.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF1394 PF07159.12 KIK35528.1 - 0.13 11.5 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1394) Ferric_reduct PF01794.19 KIK35533.1 - 8.1e-18 64.7 10.7 8.1e-18 64.7 10.7 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KIK35533.1 - 3.6e-13 49.6 0.0 6.5e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KIK35533.1 - 1.2e-08 35.3 0.0 9.3e-08 32.3 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain HTH_ABP1_N PF18107.1 KIK35534.1 - 0.017 14.8 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain AA_permease_2 PF13520.6 KIK35536.1 - 6.3e-51 173.5 58.1 7.8e-51 173.2 58.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK35536.1 - 8.2e-22 77.4 51.6 1.2e-21 76.9 51.6 1.1 1 0 0 1 1 1 1 Amino acid permease Dimer_Tnp_hAT PF05699.14 KIK35539.1 - 6.6e-12 45.1 0.1 8.7e-12 44.7 0.1 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF349 PF03993.12 KIK35540.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) DBD_Tnp_Hermes PF10683.9 KIK35542.1 - 0.041 13.6 0.1 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain RVT_2 PF07727.14 KIK35543.1 - 0.0014 18.3 0.0 0.0014 18.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GSH_synth_ATP PF03917.17 KIK35544.1 - 5.5e-58 196.5 0.0 1.3e-57 195.3 0.0 1.5 1 1 1 2 2 2 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KIK35544.1 - 5.8e-08 33.1 0.0 1.2e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DUF3593 PF12159.8 KIK35546.1 - 0.016 15.2 1.0 0.02 14.9 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) Aldo_ket_red PF00248.21 KIK35547.1 - 2e-39 135.6 0.0 1.8e-38 132.4 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family DUF1418 PF07214.12 KIK35548.1 - 0.07 13.0 1.7 0.077 12.9 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) Baculo_E56 PF04639.12 KIK35548.1 - 0.23 10.7 2.0 0.29 10.4 2.0 1.1 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope Virul_fac_BrkB PF03631.15 KIK35549.1 - 0.086 12.4 7.4 0.12 12.0 7.4 1.2 1 0 0 1 1 1 0 Virulence factor BrkB DUF1772 PF08592.11 KIK35549.1 - 0.4 11.0 3.7 0.31 11.4 2.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Tetraspanin PF00335.20 KIK35549.1 - 0.4 10.3 4.2 0.47 10.1 4.2 1.1 1 0 0 1 1 1 0 Tetraspanin family Aminotran_1_2 PF00155.21 KIK35553.1 - 5.9e-24 84.9 0.0 7.8e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KIK35553.1 - 6.9e-06 25.1 0.0 1.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase ADH_zinc_N PF00107.26 KIK35554.1 - 1.3e-08 34.9 0.1 1.7e-07 31.3 0.1 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK35554.1 - 4.4e-07 29.7 0.0 2.3e-05 24.3 0.0 2.9 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KIK35554.1 - 0.0019 17.7 0.6 0.011 15.2 0.6 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK35554.1 - 0.0022 17.6 0.0 0.0073 15.9 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N_2 PF13602.6 KIK35554.1 - 0.15 13.1 0.0 0.34 11.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AMP-binding PF00501.28 KIK35555.1 - 3.7e-18 65.3 0.2 4.4e-18 65.1 0.2 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Cauli_VI PF01693.16 KIK35557.1 - 4.8e-07 30.0 0.1 7.4e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin Dr_adhesin PF12393.8 KIK35557.1 - 0.59 10.5 3.9 1.5 9.2 3.9 1.7 1 0 0 1 1 1 0 Dr family adhesin CAF1A PF12253.8 KIK35559.1 - 0.042 14.0 0.2 0.042 14.0 0.2 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A Sdh5 PF03937.16 KIK35559.1 - 0.1 12.6 0.2 0.96 9.5 0.0 2.3 2 0 0 2 2 2 0 Flavinator of succinate dehydrogenase HTH_30 PF13556.6 KIK35560.1 - 0.022 14.5 0.2 0.054 13.3 0.2 1.7 1 1 0 1 1 1 0 PucR C-terminal helix-turn-helix domain TauD PF02668.16 KIK35561.1 - 0.022 14.5 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family KDZ PF18758.1 KIK35562.1 - 1.7e-52 178.2 0.1 3.9e-52 177.1 0.1 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK35562.1 - 4.7e-13 49.2 0.0 1.6e-12 47.5 0.0 1.9 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 KIK35562.1 - 0.019 15.1 5.2 0.019 15.1 5.2 2.3 2 0 0 2 2 2 0 B-box zinc finger Integrase_H2C2 PF17921.1 KIK35566.1 - 0.052 13.7 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 KIK35567.1 - 2.1e-10 40.5 0.0 7e-10 38.8 0.0 1.7 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KIK35567.1 - 6.8e-06 26.3 0.0 8.6e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Effector_1 PF04518.12 KIK35568.1 - 0.26 10.4 0.0 0.35 9.9 0.0 1.1 1 0 0 1 1 1 0 Effector from type III secretion system DDOST_48kD PF03345.14 KIK35571.1 - 7e-90 301.8 0.0 1e-89 301.3 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta KDZ PF18758.1 KIK35572.1 - 8.7e-20 71.3 0.1 1.9e-19 70.2 0.1 1.6 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KIK35573.1 - 1.6e-05 24.6 0.0 1.9e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase gag_pre-integrs PF13976.6 KIK35576.1 - 8.6e-07 28.7 0.0 1.3e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 KIK35578.1 - 5.4e-05 22.9 0.1 7.4e-05 22.4 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-Mss51 PF13824.6 KIK35578.1 - 0.0036 17.4 1.1 0.0068 16.5 1.1 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-CCHC_2 PF13696.6 KIK35578.1 - 0.4 10.6 6.9 0.14 12.0 2.6 2.1 2 0 0 2 2 2 0 Zinc knuckle zf-H2C2_2 PF13465.6 KIK35578.1 - 9.2 6.9 7.9 1.4 9.4 2.3 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Retrotran_gag_2 PF14223.6 KIK35579.1 - 1e-06 28.4 0.0 1.3e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UPF0640 PF15114.6 KIK35581.1 - 0.034 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0640 Helitron_like_N PF14214.6 KIK35583.1 - 2.9e-17 63.5 0.0 3.5e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus T_hemolysin PF12261.8 KIK35584.1 - 0.023 14.4 0.0 0.026 14.3 0.0 1.1 1 0 0 1 1 1 0 Thermostable hemolysin NUDE_C PF04880.13 KIK35587.1 - 0.13 12.7 0.7 0.14 12.6 0.7 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Polysacc_synt_4 PF04669.13 KIK35587.1 - 0.21 11.1 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis MFS_1 PF07690.16 KIK35589.1 - 7e-25 87.7 29.3 2.3e-14 53.1 12.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KIK35589.1 - 0.0003 19.2 0.5 0.0003 19.2 0.5 2.7 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF3932 PF13068.6 KIK35589.1 - 0.21 11.9 0.8 26 5.2 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3932) Homeodomain PF00046.29 KIK35593.1 - 1.3e-15 57.0 0.1 2.1e-15 56.3 0.1 1.3 1 0 0 1 1 1 1 Homeodomain MutS_II PF05188.17 KIK35593.1 - 0.15 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 MutS domain II Plavaka PF18759.1 KIK35594.1 - 1.1e-27 97.1 0.0 1.9e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase TPR_10 PF13374.6 KIK35596.1 - 4.3e-07 29.6 5.8 12 6.0 1.0 8.1 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK35596.1 - 0.00013 22.2 17.3 0.079 13.3 0.1 7.1 5 3 3 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIK35596.1 - 0.00017 21.3 4.9 32 4.6 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat MIT PF04212.18 KIK35596.1 - 0.00062 19.8 0.1 2.4 8.3 0.0 3.9 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 KIK35596.1 - 0.0015 18.5 6.7 23 5.4 0.0 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK35596.1 - 0.0036 17.4 0.1 1.5e+02 3.0 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK35596.1 - 0.02 15.7 16.5 15 6.7 0.1 8.1 9 1 1 10 10 10 0 Tetratricopeptide repeat DUF3849 PF12960.7 KIK35598.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) CHAT PF12770.7 KIK35601.1 - 8.8e-30 104.1 0.0 1.6e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK35601.1 - 2.3e-07 30.5 18.1 0.053 13.4 0.3 7.2 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIK35601.1 - 2.2e-05 24.1 4.2 21 5.1 0.0 7.6 8 1 0 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK35601.1 - 3.6e-05 23.6 0.0 19 5.8 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK35601.1 - 0.0002 21.2 8.1 8.5 6.8 0.0 8.7 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK35601.1 - 0.00087 19.2 4.5 5.1 7.4 0.0 5.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK35601.1 - 0.001 19.3 11.9 2.1 8.7 0.1 7.1 7 2 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK35601.1 - 0.0013 19.4 12.3 24 6.1 0.0 8.5 8 2 2 10 10 8 0 Tetratricopeptide repeat MIT PF04212.18 KIK35601.1 - 0.01 15.9 0.3 18 5.5 0.0 4.5 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 KIK35601.1 - 0.035 14.6 1.2 39 4.8 0.0 5.5 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK35601.1 - 0.12 13.1 6.9 8 7.2 0.1 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat Vta1_C PF18097.1 KIK35601.1 - 0.12 12.1 7.3 4.1 7.2 0.0 5.0 5 0 0 5 5 5 0 Vta1 C-terminal domain TPR_11 PF13414.6 KIK35601.1 - 0.15 11.8 0.0 36 4.2 0.0 4.2 4 0 0 4 4 4 0 TPR repeat 7tm_1 PF00001.21 KIK35603.1 - 0.078 12.3 4.0 0.095 12.0 2.3 2.0 1 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) FAD_binding_4 PF01565.23 KIK35604.1 - 1.9e-21 76.2 1.9 3.2e-21 75.5 1.9 1.3 1 0 0 1 1 1 1 FAD binding domain DUF3402 PF11882.8 KIK35604.1 - 0.14 11.2 0.0 14 4.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) NBD_C PF17042.5 KIK35606.1 - 0.01 16.4 0.0 0.017 15.6 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain FAM60A PF15396.6 KIK35607.1 - 0.31 11.0 11.5 0.54 10.2 11.5 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 KIK35607.1 - 0.47 9.2 17.4 0.57 8.9 17.4 1.2 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 KIK35607.1 - 0.75 8.7 13.3 1 8.3 13.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 KIK35607.1 - 0.86 7.7 15.8 1 7.4 15.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Asp-B-Hydro_N PF05279.11 KIK35607.1 - 1.1 9.3 27.1 1.5 8.9 27.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SOBP PF15279.6 KIK35607.1 - 1.5 9.4 5.4 1.9 9.0 5.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF5427 PF10310.9 KIK35607.1 - 2.5 7.0 22.6 3.2 6.6 22.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) NPR3 PF03666.13 KIK35607.1 - 4.1 6.1 15.5 5.1 5.8 15.5 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 eIF-3_zeta PF05091.12 KIK35607.1 - 4.7 6.1 16.3 6.9 5.5 16.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Gp_dh_C PF02800.20 KIK35608.1 - 1.5e-05 24.6 0.1 2e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain adh_short_C2 PF13561.6 KIK35610.1 - 8.2e-38 130.3 0.4 1e-37 130.0 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK35610.1 - 3e-32 111.7 0.3 3.9e-32 111.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK35610.1 - 1.2e-07 31.9 0.1 2.6e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KIK35610.1 - 0.00051 19.5 0.1 0.0014 18.1 0.1 1.6 1 1 1 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KIK35610.1 - 0.03 14.2 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Pex26 PF07163.12 KIK35611.1 - 0.00085 18.7 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Pex26 protein CytochromB561_N PF09786.9 KIK35611.1 - 1 8.3 15.4 0.04 12.9 9.6 1.6 2 0 0 2 2 2 0 Cytochrome B561, N terminal WD40 PF00400.32 KIK35613.1 - 4.2e-39 131.8 26.7 5.8e-07 30.1 1.3 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35613.1 - 1.9e-10 40.9 0.6 0.0097 16.2 0.0 5.2 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WW PF00397.26 KIK35613.1 - 1.4e-06 28.3 3.0 4.3e-06 26.7 0.9 2.8 2 0 0 2 2 2 1 WW domain Nup160 PF11715.8 KIK35613.1 - 0.0015 17.3 0.1 0.24 10.0 0.1 3.1 2 1 2 4 4 4 2 Nucleoporin Nup120/160 DCAF17 PF15802.5 KIK35615.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 17 Vta1_C PF18097.1 KIK35618.1 - 0.0094 15.6 0.0 0.097 12.4 0.0 2.1 2 0 0 2 2 2 1 Vta1 C-terminal domain CHAT PF12770.7 KIK35620.1 - 7.3e-11 42.0 0.0 7.8e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 CHAT domain Pkinase_fungal PF17667.1 KIK35621.1 - 1.7e-28 99.5 2.7 1.8e-23 83.0 0.2 2.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIK35621.1 - 1e-05 25.1 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain F-box PF00646.33 KIK35623.1 - 0.00023 20.9 0.2 0.00046 20.0 0.2 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK35623.1 - 0.011 15.6 0.3 0.027 14.4 0.3 1.6 1 0 0 1 1 1 0 F-box-like WD40 PF00400.32 KIK35628.1 - 5.4e-19 68.2 5.4 4.3e-10 40.0 1.3 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35628.1 - 3.5e-13 49.6 0.1 9.4e-05 22.6 0.1 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 KIK35628.1 - 7.9e-05 22.4 0.2 1.1 9.3 0.0 3.4 3 0 0 3 3 3 2 PQQ enzyme repeat Nbas_N PF15492.6 KIK35628.1 - 0.00011 21.7 0.2 0.62 9.3 0.1 3.0 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KIK35628.1 - 0.00026 20.8 0.1 2.3 8.3 0.0 3.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK35628.1 - 0.00026 20.0 0.0 0.0039 16.2 0.0 2.2 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 KIK35628.1 - 0.00062 20.2 3.6 0.062 13.8 1.9 3.0 2 1 1 3 3 3 1 PQQ-like domain WD40_like PF17005.5 KIK35628.1 - 0.0032 16.8 0.0 0.12 11.7 0.0 1.7 1 1 1 2 2 2 2 WD40-like domain RAB3GAP2_N PF14655.6 KIK35628.1 - 0.016 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus eIF2A PF08662.11 KIK35628.1 - 0.02 14.8 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK35628.1 - 0.022 13.4 0.1 2.4 6.7 0.1 2.3 2 1 1 3 3 3 0 Nucleoporin Nup120/160 HSP70 PF00012.20 KIK35631.1 - 0.013 13.8 0.0 0.017 13.4 0.0 1.0 1 0 0 1 1 1 0 Hsp70 protein Transposase_21 PF02992.14 KIK35633.1 - 3.4e-07 29.7 0.1 7.6e-07 28.6 0.1 1.5 1 0 0 1 1 1 1 Transposase family tnp2 Penicillinase_R PF03965.16 KIK35635.1 - 0.096 13.0 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Penicillinase repressor DDE_Tnp_4 PF13359.6 KIK35637.1 - 1.7e-23 83.0 0.1 2.1e-22 79.5 0.1 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease Sigma70_r4 PF04545.16 KIK35637.1 - 0.036 13.6 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 KIK35637.1 - 0.061 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Plant_tran PF04827.14 KIK35637.1 - 0.072 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Plant transposon protein Myb_DNA-bind_4 PF13837.6 KIK35638.1 - 0.028 14.8 1.0 0.22 11.9 1.0 2.6 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF2716 PF10898.8 KIK35638.1 - 0.25 11.7 2.4 5.7 7.3 0.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2716) zf-CCHC PF00098.23 KIK35640.1 - 0.01 15.9 4.5 0.017 15.1 4.5 1.4 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH_2 PF17919.1 KIK35643.1 - 1.3e-10 41.2 0.0 1.6e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Peptidase_A17 PF05380.13 KIK35643.1 - 0.0097 15.9 0.0 0.01 15.9 0.0 1.0 1 0 0 1 1 1 1 Pao retrotransposon peptidase PP2C_2 PF13672.6 KIK35643.1 - 0.037 13.7 0.0 0.037 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein phosphatase 2C RT_RNaseH PF17917.1 KIK35643.1 - 0.082 13.2 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase MucB_RseB PF03888.14 KIK35645.1 - 0.0028 17.2 0.1 0.0031 17.1 0.1 1.1 1 0 0 1 1 1 1 MucB/RseB N-terminal domain PepSY_like PF11396.8 KIK35645.1 - 0.081 13.5 0.0 0.14 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative beta-lactamase-inhibitor-like, PepSY-like Sec63 PF02889.16 KIK35649.1 - 6e-161 533.6 0.0 3.7e-89 298.3 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KIK35649.1 - 6e-48 162.9 0.1 2.7e-25 89.1 0.1 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KIK35649.1 - 4.3e-33 113.8 0.1 1.6e-32 112.0 0.0 2.1 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 KIK35649.1 - 2.4e-23 83.0 0.0 5.4e-14 52.5 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIK35649.1 - 2.2e-14 53.8 0.0 1.7e-08 34.8 0.0 3.9 3 2 0 3 3 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KIK35649.1 - 2e-06 28.1 0.1 0.08 13.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KIK35649.1 - 0.00054 19.7 0.0 0.89 9.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 KIK35649.1 - 0.00097 18.6 0.0 0.033 13.7 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_7 PF12775.7 KIK35649.1 - 0.0026 17.3 0.0 1.2 8.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region Helicase_C_2 PF13307.6 KIK35649.1 - 0.0039 17.4 0.2 8.1 6.6 0.0 3.8 3 1 1 4 4 4 1 Helicase C-terminal domain T2SSE PF00437.20 KIK35649.1 - 0.0053 15.8 0.0 0.18 10.8 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF603 PF04645.12 KIK35649.1 - 0.13 12.0 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF603 GST_N_3 PF13417.6 KIK35650.1 - 3.1e-11 43.5 0.0 5.2e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK35650.1 - 1.8e-07 31.4 0.0 3.7e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK35650.1 - 3.5e-07 30.4 0.0 6.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK35650.1 - 4.7e-06 26.5 0.0 7.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIK35650.1 - 4e-05 23.8 0.0 0.0002 21.5 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK35650.1 - 0.00026 21.1 0.0 0.00055 20.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1866 PF08952.11 KIK35652.1 - 0.047 13.5 0.1 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) VPS53_C PF16854.5 KIK35652.1 - 0.11 12.4 1.1 0.24 11.3 1.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus PIF1 PF05970.14 KIK35654.1 - 4.5e-14 52.4 1.2 3.6e-07 29.7 0.2 3.1 2 1 1 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 KIK35654.1 - 4.3e-06 26.6 0.3 0.0087 15.8 0.3 3.0 2 1 1 3 3 3 2 AAA domain NB-ARC PF00931.22 KIK35654.1 - 0.00015 21.1 0.4 0.0033 16.6 0.0 2.4 3 0 0 3 3 3 1 NB-ARC domain AAA_16 PF13191.6 KIK35654.1 - 0.0014 19.1 0.1 0.0026 18.2 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KIK35654.1 - 0.01 16.2 0.1 0.024 15.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KIK35654.1 - 0.029 13.4 0.0 0.099 11.7 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_22 PF13401.6 KIK35654.1 - 0.039 14.2 0.1 0.082 13.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KIK35654.1 - 0.05 13.3 1.5 3.5 7.3 1.5 2.3 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Transposase_21 PF02992.14 KIK35658.1 - 0.003 16.8 0.0 0.0037 16.5 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 Tox-HNH-HHH PF15637.6 KIK35659.1 - 0.31 11.2 2.4 4.5 7.5 0.1 2.6 1 1 1 2 2 2 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif TauD PF02668.16 KIK35661.1 - 4.9e-05 23.3 0.0 5.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TspO_MBR PF03073.15 KIK35663.1 - 0.01 15.9 2.3 0.014 15.5 2.2 1.4 1 1 0 1 1 1 0 TspO/MBR family Transmemb_17 PF09799.9 KIK35664.1 - 0.39 11.3 14.9 0.033 14.8 8.9 2.3 1 1 0 1 1 1 0 Predicted membrane protein AA_kinase PF00696.28 KIK35667.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Amino acid kinase family Deltaretro_Tax PF05599.11 KIK35671.1 - 0.097 13.2 0.2 0.16 12.5 0.2 1.3 1 0 0 1 1 1 0 Deltaretrovirus Tax protein Tet_JBP PF12851.7 KIK35671.1 - 0.12 11.6 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Asp_protease PF09668.10 KIK35674.1 - 0.057 13.2 0.3 0.071 12.9 0.3 1.3 1 0 0 1 1 1 0 Aspartyl protease Plavaka PF18759.1 KIK35676.1 - 9.1e-25 87.6 0.1 3e-24 85.8 0.1 1.8 1 1 0 1 1 1 1 Plavaka transposase OmdA PF13376.6 KIK35676.1 - 2.9 7.9 4.6 6.9 6.8 4.6 1.6 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Amidohydro_1 PF01979.20 KIK35678.1 - 4.2e-27 95.4 0.0 1.7e-26 93.4 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIK35678.1 - 1.9e-16 60.6 0.0 4.8e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.20 KIK35678.1 - 0.012 15.9 0.1 0.033 14.5 0.1 1.7 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain Amidohydro_2 PF04909.14 KIK35678.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase IBR PF01485.21 KIK35680.1 - 2.1e-07 31.0 6.9 2.1e-07 31.0 6.9 3.6 3 1 0 3 3 2 2 IBR domain, a half RING-finger domain DivIC PF04977.15 KIK35680.1 - 0.00024 20.8 0.3 0.00045 19.9 0.3 1.4 1 0 0 1 1 1 1 Septum formation initiator HALZ PF02183.18 KIK35680.1 - 0.0036 17.5 2.2 0.0054 16.9 0.5 2.1 2 0 0 2 2 2 1 Homeobox associated leucine zipper zf-RING_UBOX PF13445.6 KIK35680.1 - 0.0045 17.0 6.0 0.0045 17.0 6.0 4.3 3 1 1 4 4 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIK35680.1 - 0.0086 16.4 11.8 0.0086 16.4 11.8 4.0 2 1 1 3 3 3 1 Ring finger domain NRBF2 PF08961.10 KIK35680.1 - 0.013 15.1 0.1 0.024 14.3 0.1 1.3 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Surfac_D-trimer PF09006.11 KIK35680.1 - 0.1 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation bZIP_2 PF07716.15 KIK35680.1 - 0.13 12.4 1.4 0.28 11.3 1.4 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Fungal_TACC PF12709.7 KIK35680.1 - 0.18 12.3 0.2 0.4 11.2 0.2 1.5 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins GAS PF13851.6 KIK35680.1 - 0.19 11.0 1.3 0.3 10.4 0.5 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 KIK35680.1 - 1.5 9.0 5.0 0.23 11.6 1.0 1.7 2 0 0 2 2 2 0 bZIP transcription factor Cys_rich_KTR PF14205.6 KIK35680.1 - 7.2 6.5 12.8 6.9 6.5 1.4 4.0 4 0 0 4 4 4 0 Cysteine-rich KTR Amidohydro_1 PF01979.20 KIK35681.1 - 5.8e-29 101.5 0.0 2.1e-28 99.7 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIK35681.1 - 3.6e-17 63.0 0.0 1.2e-09 38.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.20 KIK35681.1 - 0.003 17.9 0.3 0.0085 16.4 0.1 1.9 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Amidohydro_2 PF04909.14 KIK35681.1 - 0.075 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase MFS_1 PF07690.16 KIK35685.1 - 2.1e-44 151.9 28.2 2.1e-44 151.9 28.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK35685.1 - 2e-09 36.8 13.0 2e-09 36.8 13.0 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 KIK35685.1 - 8.1e-05 21.6 5.1 0.19 10.6 0.1 3.3 1 1 0 2 2 2 2 MFS_1 like family TRI12 PF06609.13 KIK35685.1 - 0.00035 19.1 6.7 0.00035 19.1 6.7 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KIK35685.1 - 0.00074 18.9 7.3 0.00074 18.9 7.3 2.4 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 KIK35685.1 - 0.03 12.7 6.2 0.056 11.8 6.2 1.4 1 0 0 1 1 1 0 Transmembrane secretion effector Cpn60_TCP1 PF00118.24 KIK35686.1 - 1.7e-164 548.1 0.6 1.9e-164 547.9 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF627 PF04781.12 KIK35686.1 - 0.012 15.6 0.0 0.043 13.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF627) TPX2 PF06886.11 KIK35686.1 - 5.3 7.4 6.5 0.27 11.5 0.7 1.9 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Cys_box PF17869.1 KIK35690.1 - 0.014 15.5 1.5 0.095 12.8 0.3 2.2 2 0 0 2 2 2 0 Anosmin cysteine rich domain PTN_MK_N PF05196.13 KIK35693.1 - 0.5 10.6 4.7 1.2 9.4 4.7 1.6 1 1 0 1 1 1 0 PTN/MK heparin-binding protein family, N-terminal domain RabGAP-TBC PF00566.18 KIK35694.1 - 8.4e-49 166.1 0.0 1.2e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PriA_CRR PF18319.1 KIK35694.1 - 0.15 12.1 1.3 0.27 11.2 1.3 1.4 1 0 0 1 1 1 0 PriA DNA helicase Cys-rich region (CRR) domain DUF3530 PF12048.8 KIK35694.1 - 7.3 5.9 6.0 1.2 8.5 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) Adaptin_N PF01602.20 KIK35695.1 - 2.9e-110 369.3 0.8 3.9e-110 368.9 0.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KIK35695.1 - 2.1e-12 47.4 0.1 1.8e-07 31.4 0.0 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KIK35695.1 - 3.5e-07 29.9 2.3 1.3 9.5 0.0 5.8 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 KIK35695.1 - 6.9e-07 29.6 1.9 0.067 13.6 0.2 5.2 3 2 3 6 6 6 2 HEAT repeats RTP1_C1 PF10363.9 KIK35695.1 - 3.9e-05 23.8 0.7 0.33 11.2 0.0 3.5 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Proteasom_PSMB PF10508.9 KIK35695.1 - 0.0006 18.4 1.9 0.04 12.4 0.8 2.6 2 1 0 2 2 2 2 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.6 KIK35695.1 - 0.012 16.1 7.9 2.5 8.7 0.0 6.4 7 0 0 7 7 7 0 HEAT-like repeat Nipped-B_C PF12830.7 KIK35695.1 - 0.11 12.4 3.0 4 7.3 0.0 3.4 3 1 1 4 4 4 0 Sister chromatid cohesion C-terminus DUF1682 PF07946.14 KIK35695.1 - 0.13 11.4 3.2 0.23 10.6 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Elf1 PF05129.13 KIK35698.1 - 0.02 14.9 0.6 0.048 13.7 0.6 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 KIK35698.1 - 0.089 12.9 2.5 2 8.6 2.6 2.5 1 1 1 2 2 2 0 Zinc ribbon domain Mce4_CUP1 PF11887.8 KIK35699.1 - 0.061 12.8 0.0 0.088 12.2 0.0 1.2 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Pkinase_Tyr PF07714.17 KIK35701.1 - 7.4e-31 107.4 0.0 8.8e-31 107.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK35701.1 - 4.8e-26 91.7 0.0 5.6e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK35701.1 - 0.00072 19.0 0.0 0.00097 18.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK35701.1 - 0.0014 17.5 0.0 0.0016 17.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIK35701.1 - 0.0035 16.7 0.0 0.0042 16.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIK35701.1 - 0.019 14.9 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KIK35701.1 - 0.041 13.5 0.0 0.053 13.1 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 KIK35702.1 - 1.1e-30 106.9 0.0 1.3e-30 106.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK35702.1 - 9.1e-29 100.6 0.0 1.2e-28 100.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK35702.1 - 7.6e-05 21.7 0.0 0.0001 21.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIK35702.1 - 0.00014 21.3 0.0 0.0002 20.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK35702.1 - 0.0013 18.7 0.0 0.0018 18.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK35702.1 - 0.002 17.7 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KIK35702.1 - 0.044 13.1 0.0 0.057 12.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 KIK35702.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 zf-MYND PF01753.18 KIK35703.1 - 3.2e-09 36.7 12.4 6e-09 35.8 12.4 1.5 1 0 0 1 1 1 1 MYND finger PI3K_C2 PF00792.24 KIK35703.1 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 MFS_1 PF07690.16 KIK35705.1 - 3.7e-28 98.5 38.6 4.8e-28 98.1 38.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK35705.1 - 3.1e-05 22.6 2.6 3.1e-05 22.6 2.6 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) NSP10 PF09401.10 KIK35707.1 - 0.012 15.7 0.3 0.052 13.6 0.2 1.9 1 1 1 2 2 2 0 RNA synthesis protein NSP10 DUF1391 PF07151.12 KIK35707.1 - 0.012 15.4 0.1 0.02 14.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) WD40 PF00400.32 KIK35708.1 - 7.8e-16 58.2 2.8 3.2e-10 40.4 0.0 3.5 3 1 1 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35708.1 - 0.042 14.2 0.0 0.091 13.1 0.0 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK35708.1 - 0.15 12.0 6.5 1.6 8.7 0.1 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat VirK PF06903.12 KIK35708.1 - 0.16 12.1 0.0 0.46 10.6 0.0 1.7 1 1 0 1 1 1 0 VirK protein Oxidored_FMN PF00724.20 KIK35709.1 - 1.7e-96 323.5 0.0 2e-96 323.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.21 KIK35709.1 - 0.083 12.8 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Tautomerase enzyme WD40 PF00400.32 KIK35712.1 - 1.4e-14 54.2 5.5 7.3e-08 33.0 0.9 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KIK35712.1 - 1.2e-05 24.5 0.1 0.021 13.8 0.0 2.1 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK35712.1 - 1.9e-05 24.5 0.1 0.13 12.2 0.0 2.4 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 KIK35712.1 - 0.00058 20.1 0.0 0.23 11.8 0.0 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain NopRA1 PF16201.5 KIK35713.1 - 1.5e-11 44.3 0.0 2.5e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 2CSK_N PF08521.10 KIK35717.1 - 0.08 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal Pkinase PF00069.25 KIK35718.1 - 4.6e-26 91.8 0.0 5e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK35718.1 - 4.7e-13 49.0 0.0 5.1e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK35718.1 - 2.4e-06 26.6 0.0 2.6e-06 26.5 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIK35718.1 - 0.0014 18.0 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK35718.1 - 0.0022 17.4 0.0 0.0024 17.2 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIK35718.1 - 0.0047 15.9 0.2 0.0057 15.6 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Polysacc_synt_C PF14667.6 KIK35719.1 - 0.0032 17.5 21.2 0.05 13.7 5.1 2.6 1 1 1 2 2 2 2 Polysaccharide biosynthesis C-terminal domain GWT1 PF06423.12 KIK35719.1 - 6.3 6.9 10.7 6.3 6.9 8.1 2.2 1 1 1 2 2 2 0 GWT1 WD40 PF00400.32 KIK35720.1 - 1.5e-19 70.0 0.4 3.3e-05 24.5 0.0 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35720.1 - 3e-08 33.8 0.0 0.0046 17.2 0.0 2.8 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK35720.1 - 0.0011 18.8 0.0 0.083 12.8 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK35720.1 - 0.0024 16.9 0.1 1.3 7.9 0.0 3.0 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK35720.1 - 0.097 12.6 3.7 12 6.0 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 KIK35721.1 - 2.6e-11 43.9 0.5 2.2e-08 34.6 0.2 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35721.1 - 0.00025 21.3 0.4 0.72 10.2 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 KIK35721.1 - 0.031 13.9 0.1 0.038 13.6 0.1 1.0 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region ESPR PF13018.6 KIK35721.1 - 0.089 12.6 0.7 0.17 11.7 0.7 1.5 1 0 0 1 1 1 0 Extended Signal Peptide of Type V secretion system Formyl_trans_C PF02911.18 KIK35721.1 - 0.1 12.8 0.0 0.31 11.3 0.0 1.7 1 1 0 1 1 1 0 Formyl transferase, C-terminal domain WD40 PF00400.32 KIK35723.1 - 1.9e-51 170.9 18.7 3e-08 34.2 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35723.1 - 1.5e-24 86.1 0.5 0.00034 20.9 0.0 6.5 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK35723.1 - 6.7e-12 45.0 1.2 0.0057 15.7 0.0 5.4 1 1 5 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK35723.1 - 3.2e-07 30.4 0.0 0.87 9.4 0.0 3.4 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK35723.1 - 1.7e-05 23.7 4.5 0.88 8.1 0.0 5.0 4 2 1 5 5 5 2 Nucleoporin Nup120/160 PD40 PF07676.12 KIK35723.1 - 3.7e-05 23.5 0.1 29 4.7 0.1 5.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 KIK35723.1 - 0.00011 21.9 2.1 0.03 13.9 0.4 2.7 1 1 0 2 2 2 2 PQQ-like domain Frtz PF11768.8 KIK35723.1 - 0.00026 19.4 0.0 1 7.6 0.0 3.5 1 1 2 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK35723.1 - 0.00045 19.6 0.0 2.1 7.6 0.0 3.3 3 1 1 4 4 4 2 WD40-like domain Nbas_N PF15492.6 KIK35723.1 - 0.0024 17.3 0.1 13 5.0 0.0 3.7 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 KIK35723.1 - 0.01 14.4 0.1 0.022 13.3 0.1 1.6 1 0 0 1 1 1 1 Cytochrome D1 heme domain DUF5046 PF16465.5 KIK35723.1 - 0.018 14.5 0.0 0.038 13.4 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5046) DegT_DnrJ_EryC1 PF01041.17 KIK35723.1 - 0.096 12.0 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family FlgT_M PF16539.5 KIK35724.1 - 0.13 12.4 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein T, middle domain AAA_lid_9 PF17871.1 KIK35727.1 - 9.6e-25 86.5 0.4 9.6e-25 86.5 0.4 1.8 2 0 0 2 2 1 1 AAA lid domain AAA_2 PF07724.14 KIK35727.1 - 1.4e-18 67.6 0.0 1.8e-16 60.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KIK35727.1 - 1.9e-08 34.9 1.3 2.6e-06 27.9 0.1 3.2 3 0 0 3 3 3 1 AAA ATPase domain ClpB_D2-small PF10431.9 KIK35727.1 - 7.2e-08 32.4 0.3 7.2e-08 32.4 0.3 2.8 3 0 0 3 3 3 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KIK35727.1 - 9.3e-08 32.6 0.1 9.3e-05 22.9 0.0 3.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KIK35727.1 - 0.00061 19.1 0.1 0.58 9.3 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 KIK35727.1 - 0.0012 19.1 0.0 0.5 10.5 0.0 3.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KIK35727.1 - 0.0024 17.6 0.0 0.037 13.7 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 KIK35727.1 - 0.0034 17.6 0.0 0.071 13.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KIK35727.1 - 0.004 16.7 0.1 2.6 7.5 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_5 PF07728.14 KIK35727.1 - 0.011 15.8 0.1 0.18 11.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KIK35727.1 - 0.011 15.0 0.0 0.94 8.7 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 KIK35727.1 - 0.013 16.1 0.0 0.19 12.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KIK35727.1 - 0.025 14.5 0.8 0.56 10.1 0.1 2.9 2 0 0 2 2 2 0 NACHT domain DUF3860 PF12976.7 KIK35727.1 - 0.034 14.2 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) ATPase_2 PF01637.18 KIK35727.1 - 0.035 14.0 0.0 0.035 14.0 0.0 2.4 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea CbiA PF01656.23 KIK35727.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TsaE PF02367.17 KIK35727.1 - 0.053 13.5 0.1 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 KIK35727.1 - 0.096 12.4 0.0 0.63 9.8 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 KIK35727.1 - 0.11 12.4 0.1 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase DUF1730 PF08331.10 KIK35727.1 - 0.15 11.9 0.3 0.56 10.1 0.1 2.1 2 0 0 2 2 1 0 Domain of unknown function (DUF1730) RNA_helicase PF00910.22 KIK35727.1 - 0.16 12.3 0.1 2.1 8.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 KIK35727.1 - 0.55 9.8 1.9 0.96 9.0 0.0 2.5 3 0 0 3 3 2 0 AAA domain Clp_N PF02861.20 KIK35727.1 - 4.8 7.4 7.0 2.2 8.5 0.7 2.9 3 0 0 3 3 2 0 Clp amino terminal domain, pathogenicity island component PSP1 PF04468.12 KIK35729.1 - 0.22 11.8 3.1 0.32 11.3 3.1 1.5 1 1 0 1 1 1 0 PSP1 C-terminal conserved region DDE_Tnp_4 PF13359.6 KIK35730.1 - 3.7e-14 52.7 0.0 4e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_4 PF13359.6 KIK35731.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_3 PF13358.6 KIK35733.1 - 6.5e-06 26.0 0.0 6.6e-06 25.9 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KIK35734.1 - 0.00021 21.8 0.7 0.0018 18.9 0.3 2.3 1 1 1 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KIK35734.1 - 0.0056 16.9 0.1 0.015 15.5 0.0 1.8 1 1 0 1 1 1 1 Transposase HTH_29 PF13551.6 KIK35734.1 - 0.011 15.7 0.1 0.028 14.4 0.1 1.8 1 1 0 1 1 1 0 Winged helix-turn helix HTH_23 PF13384.6 KIK35734.1 - 0.044 13.6 0.1 0.21 11.4 0.1 2.1 1 1 1 2 2 2 0 Homeodomain-like domain HTH_7 PF02796.15 KIK35734.1 - 0.075 13.1 0.1 0.75 9.9 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase DUF4111 PF13427.6 KIK35734.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) DUF1163 PF06651.11 KIK35736.1 - 0.084 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1163) Pkinase_fungal PF17667.1 KIK35737.1 - 1.2e-30 106.7 0.3 1.2e-28 100.1 0.1 2.1 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 KIK35737.1 - 0.0002 21.3 0.0 0.00031 20.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK35738.1 - 5.8e-19 68.2 0.0 6.6e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase FAD_binding_6 PF00970.24 KIK35738.1 - 0.059 13.7 0.0 0.081 13.3 0.0 1.2 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain WD40 PF00400.32 KIK35740.1 - 4.8e-06 27.2 0.1 0.91 10.5 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35740.1 - 6.8e-06 26.3 0.1 0.63 10.4 0.1 3.7 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 KIK35740.1 - 0.069 13.1 0.5 0.45 10.5 0.0 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat PQQ_3 PF13570.6 KIK35740.1 - 0.12 12.9 0.3 5.5 7.6 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain CPP1-like PF11833.8 KIK35741.1 - 9.5 5.8 11.9 0.53 9.9 1.8 2.4 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like SH3_7 PF12914.7 KIK35745.1 - 0.074 13.2 0.0 0.19 11.9 0.0 1.7 2 0 0 2 2 2 0 SH3 domain of SH3b2 type Exo_endo_phos PF03372.23 KIK35748.1 - 0.0027 17.3 0.0 0.0055 16.2 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Phlebovirus_NSM PF07246.11 KIK35748.1 - 0.1 12.0 0.7 0.23 10.8 0.7 1.6 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M RVT_1 PF00078.27 KIK35749.1 - 0.0024 17.4 0.1 0.0044 16.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EST1_DNA_bind PF10373.9 KIK35749.1 - 0.025 14.1 0.5 0.033 13.7 0.5 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain DUF2464 PF10240.9 KIK35749.1 - 0.064 12.8 0.4 0.084 12.4 0.4 1.1 1 0 0 1 1 1 0 Multivesicular body subunit 12 RVT_1 PF00078.27 KIK35750.1 - 5.2e-08 32.7 0.0 1.1e-07 31.6 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF445 PF04286.12 KIK35750.1 - 0.14 11.9 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) YwqJ-deaminase PF14431.6 KIK35754.1 - 0.17 12.1 0.1 0.27 11.4 0.1 1.2 1 0 0 1 1 1 0 YwqJ-like deaminase CUE PF02845.16 KIK35755.1 - 0.037 13.7 0.0 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 CUE domain TCTP PF00838.17 KIK35756.1 - 0.0049 17.2 0.2 0.0077 16.6 0.2 1.3 1 0 0 1 1 1 1 Translationally controlled tumour protein DUF1398 PF07166.11 KIK35756.1 - 0.06 13.4 1.0 0.11 12.5 0.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1398) HTH_Tnp_4 PF13613.6 KIK35758.1 - 0.00035 20.2 0.0 0.00049 19.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_4 PF13359.6 KIK35759.1 - 0.024 14.3 0.0 0.025 14.2 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_Tnp_4 PF13359.6 KIK35760.1 - 0.15 11.7 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease DGF-1_4 PF11024.8 KIK35761.1 - 0.057 14.2 1.0 0.12 13.2 1.0 1.6 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 Myb_DNA-bind_4 PF13837.6 KIK35762.1 - 1.9e-06 28.1 0.2 1.9e-05 24.9 0.2 2.3 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 KIK35762.1 - 0.0039 18.1 0.3 0.0059 17.6 0.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 KIK35762.1 - 0.042 14.0 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK35762.1 - 0.046 14.0 0.1 0.091 13.0 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 KIK35762.1 - 0.086 13.2 0.3 0.21 11.9 0.2 1.7 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Plavaka PF18759.1 KIK35763.1 - 6.5e-22 78.2 0.0 1.2e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK35764.1 - 3.8e-25 88.8 0.0 4.4e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase WD40 PF00400.32 KIK35766.1 - 7.7e-09 36.0 0.6 0.00018 22.2 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat AAA_12 PF13087.6 KIK35766.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain KOW PF00467.29 KIK35767.1 - 3.3e-08 33.2 15.3 0.42 10.6 0.2 6.4 7 0 0 7 7 7 4 KOW motif DUF4736 PF15883.5 KIK35769.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) KDZ PF18758.1 KIK35771.1 - 1.5e-47 162.1 1.2 1.7e-47 161.9 1.2 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KIK35772.1 - 4.4e-26 91.9 0.0 5.7e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK35772.1 - 2.4e-05 24.4 0.1 4.3e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases DUF4473 PF14747.6 KIK35773.1 - 0.15 12.7 0.8 0.38 11.3 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) GST_C PF00043.25 KIK35775.1 - 0.00023 21.3 0.0 0.00038 20.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK35775.1 - 0.00056 20.1 0.0 0.00094 19.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK35775.1 - 0.0018 18.3 0.1 0.0024 17.9 0.1 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FoP_duplication PF13865.6 KIK35777.1 - 0.0038 17.7 3.8 0.0092 16.5 3.8 1.7 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 FXMRP1_C_core PF12235.8 KIK35777.1 - 0.031 14.9 3.3 0.031 14.9 3.3 2.0 2 1 0 2 2 2 0 Fragile X-related 1 protein core C terminal RED_C PF07807.11 KIK35778.1 - 1.9 9.0 7.9 3.6 8.1 7.9 1.5 1 0 0 1 1 1 0 RED-like protein C-terminal region Nucleoside_tran PF01733.18 KIK35779.1 - 1.2e-37 130.0 10.3 1.2e-37 130.0 10.3 1.9 2 1 0 2 2 2 1 Nucleoside transporter Nucleoside_tran PF01733.18 KIK35780.1 - 2.1e-31 109.5 11.2 2.1e-31 109.5 11.2 2.8 1 1 1 2 2 2 1 Nucleoside transporter Vfa1 PF08432.10 KIK35781.1 - 2.9e-36 125.5 1.0 3.4e-36 125.3 1.0 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF775 PF05603.12 KIK35781.1 - 0.0062 16.1 0.0 0.0065 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF775) ANAPC_CDC26 PF10471.9 KIK35781.1 - 0.024 15.5 3.0 0.046 14.6 0.6 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 CDC45 PF02724.14 KIK35781.1 - 0.91 7.7 4.4 1.1 7.5 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Rtf2 PF04641.12 KIK35781.1 - 1.3 8.4 11.5 1.4 8.2 11.5 1.3 1 1 0 1 1 1 0 Rtf2 RING-finger ADH_N PF08240.12 KIK35782.1 - 7.1e-25 87.0 2.2 1.6e-24 85.9 2.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK35782.1 - 1.4e-18 67.1 0.1 3.6e-18 65.8 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KIK35782.1 - 0.00091 18.6 0.1 0.0015 17.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1686 PF07937.11 KIK35782.1 - 0.014 15.2 0.8 3.5 7.5 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1686) AlaDh_PNT_C PF01262.21 KIK35782.1 - 0.023 14.0 0.5 0.046 13.0 0.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 KIK35782.1 - 0.043 13.2 1.8 0.098 12.0 1.8 1.6 1 0 0 1 1 1 0 ThiF family CLLAC PF15675.5 KIK35782.1 - 0.47 10.1 2.5 1 9.0 2.5 1.5 1 0 0 1 1 1 0 CLLAC-motif containing domain ACBP PF00887.19 KIK35783.1 - 1.3e-21 76.5 0.0 2.5e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein DUF4349 PF14257.6 KIK35783.1 - 0.032 13.7 0.0 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) BORCS6 PF10157.9 KIK35783.1 - 0.053 13.7 1.1 0.18 12.0 1.0 1.8 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 6 MRP-S34 PF16053.5 KIK35784.1 - 2.3e-11 43.5 0.8 2.9e-11 43.1 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 DUF1663 PF07909.11 KIK35785.1 - 0.048 12.4 0.0 0.062 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1663) MapZ_EC1 PF18041.1 KIK35785.1 - 0.24 11.7 0.0 0.31 11.3 0.0 1.1 1 0 0 1 1 1 0 MapZ extracellular domain 1 dUTPase PF00692.19 KIK35786.1 - 4.2e-43 146.1 0.0 7.7e-43 145.3 0.0 1.4 2 0 0 2 2 2 1 dUTPase Sugar_tr PF00083.24 KIK35788.1 - 4e-98 329.2 28.9 5.1e-98 328.9 28.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK35788.1 - 4.5e-29 101.5 65.7 1.7e-26 93.0 33.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 KIK35788.1 - 0.014 15.6 0.7 0.014 15.6 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) UNC-93 PF05978.16 KIK35788.1 - 0.03 14.0 15.2 1.1 9.0 0.1 3.8 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 SAM_3 PF18016.1 KIK35788.1 - 0.14 12.0 0.0 0.43 10.4 0.0 1.8 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Thump_like PF18096.1 KIK35793.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 THUMP domain-like Plavaka PF18759.1 KIK35794.1 - 5.3e-108 361.1 0.2 7.5e-72 242.3 0.1 2.2 1 1 1 2 2 2 2 Plavaka transposase Ras PF00071.22 KIK35795.1 - 8.7e-11 41.7 0.6 3.9e-08 33.1 0.1 2.5 2 1 1 3 3 3 2 Ras family Roc PF08477.13 KIK35795.1 - 0.00022 21.4 0.1 0.019 15.2 0.0 2.1 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Cep57_MT_bd PF06657.13 KIK35796.1 - 0.082 13.4 1.7 0.38 11.2 1.8 2.1 1 1 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 KDZ PF18758.1 KIK35799.1 - 2.8e-52 177.6 1.4 5.2e-48 163.6 0.2 2.2 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase FRP PF18032.1 KIK35799.1 - 0.054 14.1 0.4 9.7 6.9 0.0 2.4 1 1 0 2 2 2 0 Photoprotection regulator fluorescence recovery protein CxC1 PF18802.1 KIK35800.1 - 0.0029 17.8 0.5 0.0066 16.6 0.5 1.7 1 1 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases PHINT_rpt PF14882.6 KIK35800.1 - 0.021 15.1 0.0 0.051 13.8 0.0 1.6 1 0 0 1 1 1 0 Phage-integrase repeat unit SecY PF00344.20 KIK35803.1 - 1.1e-73 248.1 10.4 1.4e-73 247.8 10.4 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KIK35803.1 - 4e-19 68.1 0.1 2.2e-18 65.8 0.2 2.2 2 0 0 2 2 2 1 Plug domain of Sec61p DUF805 PF05656.14 KIK35803.1 - 0.32 11.4 5.4 0.42 11.1 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF805) WD40 PF00400.32 KIK35804.1 - 1.3e-33 114.4 28.2 5.3e-07 30.2 0.2 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 KIK35804.1 - 2.3e-14 53.0 2.3 8.1e-14 51.2 2.3 2.1 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KIK35804.1 - 7.7e-12 45.4 3.5 0.0023 18.2 0.0 5.6 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KIK35804.1 - 3.8e-07 29.8 1.0 8.7e-07 28.7 1.0 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KIK35804.1 - 9e-06 24.6 9.0 0.21 10.2 0.1 4.4 2 1 2 5 5 5 4 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK35804.1 - 3.4e-05 23.3 0.2 0.015 14.6 0.0 3.2 2 1 1 3 3 3 2 WD40-like domain F-box_5 PF18511.1 KIK35804.1 - 9.9e-05 21.8 0.3 0.00049 19.6 0.1 2.2 2 0 0 2 2 2 1 F-box PQQ_3 PF13570.6 KIK35804.1 - 0.0002 21.7 2.7 2 9.0 0.3 4.8 5 1 0 5 5 5 1 PQQ-like domain TPR_1 PF00515.28 KIK35805.1 - 6.9e-29 98.5 1.1 1.8e-05 24.3 0.1 8.1 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 KIK35805.1 - 1.2e-28 96.8 6.4 0.00018 21.4 0.0 8.9 9 0 0 9 9 8 5 Tetratricopeptide repeat DnaJ PF00226.31 KIK35805.1 - 5.6e-21 74.4 0.4 1.1e-20 73.4 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_9 PF13371.6 KIK35805.1 - 1.9e-16 60.0 12.5 3.4e-06 27.1 0.9 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIK35805.1 - 2.4e-16 60.1 18.9 9.5e-05 23.0 0.6 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIK35805.1 - 2.4e-15 56.6 19.0 0.0034 17.6 1.5 6.3 4 3 2 6 6 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 KIK35805.1 - 3.3e-15 55.5 3.8 4.9e-07 29.3 0.1 6.7 6 1 1 7 7 7 3 TPR repeat TPR_8 PF13181.6 KIK35805.1 - 3.8e-13 48.5 0.9 0.013 15.7 0.1 7.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK35805.1 - 5.4e-12 46.0 17.3 0.0037 17.7 0.5 6.2 4 3 2 7 7 7 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK35805.1 - 6.6e-12 45.5 6.8 0.013 15.7 0.1 4.8 4 2 2 6 6 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KIK35805.1 - 1.3e-10 41.2 17.8 0.091 13.6 0.1 7.2 5 3 3 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 KIK35805.1 - 8.7e-08 32.0 5.0 0.17 12.3 0.0 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIK35805.1 - 3.8e-06 27.2 2.8 0.35 11.6 0.0 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 KIK35805.1 - 2.2e-05 23.8 0.7 1.6 8.2 0.0 4.2 4 0 0 4 4 3 2 SHNi-TPR TPR_7 PF13176.6 KIK35805.1 - 0.0028 17.6 9.4 2.7 8.2 0.0 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KIK35805.1 - 0.003 17.6 4.1 0.12 12.4 1.7 3.2 2 2 1 3 3 3 1 Putative TPR-like repeat MIT PF04212.18 KIK35805.1 - 0.0061 16.6 4.6 0.15 12.2 0.1 4.2 4 1 0 4 4 3 1 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 KIK35805.1 - 0.0094 16.0 9.1 4.7 7.4 0.0 5.7 7 0 0 7 7 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KIK35805.1 - 0.078 12.9 13.5 5 7.1 0.2 5.8 6 1 0 7 7 6 0 Tetratricopeptide repeat LPD14 PF18827.1 KIK35805.1 - 0.09 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 14 ABC_tran_CTD PF16326.5 KIK35805.1 - 0.16 12.2 2.9 0.35 11.1 0.4 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain CcmF_C PF16327.5 KIK35805.1 - 0.26 10.5 0.1 0.4 9.9 0.1 1.2 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal Ead_Ea22 PF13935.6 KIK35805.1 - 0.48 11.1 4.2 0.43 11.2 2.1 2.0 2 1 0 2 2 2 0 Ead/Ea22-like protein TPR_3 PF07720.12 KIK35805.1 - 2.9 8.0 4.9 15 5.7 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_pol_delta_4 PF04081.13 KIK35807.1 - 3.2e-31 108.4 0.7 1e-30 106.7 0.7 1.9 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 FAD_binding_3 PF01494.19 KIK35809.1 - 1.2e-78 264.9 0.0 1.6e-78 264.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KIK35809.1 - 3.6e-35 121.5 0.0 6.2e-35 120.7 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 KIK35809.1 - 1.5e-06 27.2 0.4 2.7e-06 26.4 0.4 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KIK35809.1 - 5.3e-06 26.9 0.4 0.0055 17.2 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK35809.1 - 2.2e-05 23.8 0.1 3.7e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KIK35809.1 - 2.9e-05 24.2 0.1 8.2e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK35809.1 - 3.2e-05 23.3 0.1 0.00011 21.6 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK35809.1 - 5.5e-05 22.4 1.7 9.3e-05 21.7 1.7 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KIK35809.1 - 0.0013 18.1 0.2 0.002 17.4 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK35809.1 - 0.002 17.2 1.2 0.0051 15.9 0.7 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KIK35809.1 - 0.0022 17.6 0.5 0.0041 16.8 0.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIK35809.1 - 0.005 15.7 0.1 0.0071 15.2 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.22 KIK35809.1 - 0.0086 15.2 0.8 0.014 14.5 0.8 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KIK35809.1 - 0.019 14.3 0.2 0.031 13.6 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KIK35809.1 - 0.033 13.6 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase SE PF08491.10 KIK35809.1 - 0.058 12.4 0.0 0.71 8.9 0.0 2.0 1 1 0 1 1 1 0 Squalene epoxidase NAD_binding_9 PF13454.6 KIK35809.1 - 0.092 12.7 0.1 0.26 11.2 0.1 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KIK35809.1 - 0.12 11.9 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KIK35809.1 - 0.17 11.8 0.1 0.28 11.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KIK35809.1 - 0.2 11.3 0.1 0.32 10.6 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Transposase_21 PF02992.14 KIK35812.1 - 1.1e-06 28.0 0.1 1.7e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Transposase family tnp2 Plavaka PF18759.1 KIK35812.1 - 0.015 14.6 0.4 0.017 14.4 0.4 1.1 1 0 0 1 1 1 0 Plavaka transposase RTC PF01137.21 KIK35812.1 - 0.15 11.3 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase SesA PF17107.5 KIK35813.1 - 0.025 14.8 0.0 0.13 12.4 0.0 2.0 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases BASP1 PF05466.12 KIK35816.1 - 0.029 14.4 3.9 0.035 14.1 3.9 1.1 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) DUF1179 PF06678.11 KIK35816.1 - 0.1 12.6 1.6 0.2 11.7 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) gag-asp_proteas PF13975.6 KIK35816.1 - 0.17 12.4 0.5 0.38 11.3 0.4 1.7 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Retrotran_gag_2 PF14223.6 KIK35817.1 - 1.1e-15 57.6 0.0 1.4e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type GMC_oxred_N PF00732.19 KIK35819.1 - 5.1e-58 196.8 0.0 6.6e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK35819.1 - 9.9e-05 22.9 0.0 0.00021 21.8 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK35819.1 - 0.003 16.7 0.0 0.0094 15.0 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK35819.1 - 0.066 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain pKID PF02173.17 KIK35819.1 - 0.19 11.2 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 pKID domain GMC_oxred_C PF05199.13 KIK35820.1 - 2e-14 54.3 0.1 2.2e-14 54.2 0.1 1.0 1 0 0 1 1 1 1 GMC oxidoreductase RTC4 PF14474.6 KIK35820.1 - 0.099 12.8 0.0 0.099 12.8 0.0 1.1 1 0 0 1 1 1 0 RTC4-like domain p450 PF00067.22 KIK35825.1 - 8.9e-75 252.2 0.0 1e-74 252.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Arteri_Gl PF00951.18 KIK35827.1 - 1.4 8.7 12.1 1.3 8.8 10.8 1.6 1 1 0 1 1 1 0 Arterivirus GL envelope glycoprotein Halogen_Hydrol PF10112.9 KIK35827.1 - 3.4 7.6 4.4 1.8 8.5 0.2 2.2 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF4421 PF14391.6 KIK35828.1 - 0.019 14.3 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4421) FeThRed_A PF02941.15 KIK35828.1 - 0.17 12.0 0.0 0.73 10.0 0.0 1.9 2 0 0 2 2 2 0 Ferredoxin thioredoxin reductase variable alpha chain YWFCY PF14293.6 KIK35829.1 - 7.8 6.9 7.6 23 5.4 1.1 3.0 3 0 0 3 3 3 0 YWFCY protein Plavaka PF18759.1 KIK35833.1 - 9.4e-38 130.2 0.0 1.2e-37 129.9 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase HEAT_2 PF13646.6 KIK35837.1 - 0.033 14.6 0.0 1.8 9.0 0.0 2.7 2 0 0 2 2 2 0 HEAT repeats AAA PF00004.29 KIK35840.1 - 0.0017 18.8 0.0 0.0032 17.9 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIK35840.1 - 0.066 13.2 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KIK35840.1 - 0.089 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF4276 PF14103.6 KIK35840.1 - 0.091 13.0 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) RuvB_N PF05496.12 KIK35840.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_8 PF12780.7 KIK35840.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Pyr_redox_2 PF07992.14 KIK35842.1 - 8.6e-18 64.6 0.2 5.1e-14 52.2 0.1 2.7 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK35842.1 - 1.6e-17 63.7 0.1 5.4e-10 39.0 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KIK35842.1 - 5.7e-17 61.3 0.1 1.9e-14 53.0 0.0 2.8 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KIK35842.1 - 9.1e-14 51.3 0.0 1e-10 41.3 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KIK35842.1 - 2.3e-07 31.3 0.4 0.0051 17.3 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK35842.1 - 4.1e-07 30.1 0.0 1.9e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KIK35842.1 - 1.1e-06 28.1 0.5 1.9e-06 27.4 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KIK35842.1 - 1.8e-06 27.0 2.4 0.00012 20.9 0.3 2.9 3 1 1 4 4 4 1 HI0933-like protein Shikimate_DH PF01488.20 KIK35842.1 - 3e-06 27.3 0.2 0.00031 20.8 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 KIK35842.1 - 3.1e-06 27.0 2.1 0.0024 17.5 0.3 3.4 1 1 2 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIK35842.1 - 4.6e-06 26.7 0.1 0.023 14.7 0.0 3.6 3 1 1 4 4 4 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KIK35842.1 - 9.5e-05 22.8 0.0 0.058 13.8 0.0 2.5 3 0 0 3 3 2 1 Putative NAD(P)-binding Thi4 PF01946.17 KIK35842.1 - 0.0044 16.3 0.0 0.03 13.6 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KIK35842.1 - 0.0047 16.1 2.2 0.0073 15.4 0.6 2.1 2 1 1 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 KIK35842.1 - 0.007 15.8 0.2 0.011 15.1 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KIK35842.1 - 0.0086 15.2 2.9 0.43 9.6 0.1 3.1 3 1 1 4 4 4 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 KIK35842.1 - 0.011 15.0 0.0 3.7 6.9 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KIK35842.1 - 0.015 14.4 0.8 0.3 10.1 0.0 2.9 4 0 0 4 4 4 0 Lycopene cyclase protein TrkA_N PF02254.18 KIK35842.1 - 0.023 14.9 0.1 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Trp_halogenase PF04820.14 KIK35842.1 - 0.035 13.0 0.8 0.09 11.6 0.2 1.9 3 0 0 3 3 3 0 Tryptophan halogenase Peptidase_M17_N PF02789.17 KIK35842.1 - 0.082 12.8 0.3 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain ThiF PF00899.21 KIK35842.1 - 0.11 11.8 0.0 6.8 6.0 0.0 2.2 2 0 0 2 2 2 0 ThiF family AlaDh_PNT_C PF01262.21 KIK35842.1 - 0.21 10.9 0.3 0.62 9.3 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Rubredoxin_2 PF18073.1 KIK35845.1 - 0.052 13.3 1.8 0.11 12.3 1.8 1.5 1 0 0 1 1 1 0 Rubredoxin metal binding domain CHAT PF12770.7 KIK35846.1 - 7.3e-45 153.6 0.0 9.4e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 CHAT domain Peptidase_C25 PF01364.18 KIK35846.1 - 0.037 13.2 0.0 0.051 12.8 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C25 Transposase_21 PF02992.14 KIK35849.1 - 1.6e-05 24.2 0.0 3.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Transposase family tnp2 Trypan_PARP PF05887.11 KIK35849.1 - 0.011 15.7 4.0 0.018 15.0 4.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Zmiz1_N PF18028.1 KIK35851.1 - 0.13 12.5 0.0 0.23 11.8 0.0 1.5 1 1 0 1 1 1 0 Zmiz1 N-terminal tetratricopeptide repeat domain DUF5552 PF17706.1 KIK35852.1 - 0.056 13.2 0.1 0.056 13.2 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5552) DDE_1 PF03184.19 KIK35854.1 - 6.6e-22 78.0 0.1 9.6e-22 77.5 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3656 PF12392.8 KIK35854.1 - 0.038 14.6 0.0 0.062 14.0 0.0 1.4 1 0 0 1 1 1 0 Collagenase RE_Eco47II PF09553.10 KIK35856.1 - 0.043 13.4 0.4 13 5.3 0.0 2.7 1 1 2 3 3 3 0 Eco47II restriction endonuclease DUF2884 PF11101.8 KIK35857.1 - 0.066 12.7 0.1 0.2 11.2 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) AMP-binding PF00501.28 KIK35860.1 - 1.6e-76 257.6 0.0 2.1e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK35860.1 - 1.1e-08 35.9 0.0 2.5e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GATA PF00320.27 KIK35864.1 - 4.9e-25 86.8 20.0 5.5e-15 54.7 3.7 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 KIK35864.1 - 1.6e-11 43.8 0.7 3.6e-11 42.7 0.7 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Zn-ribbon_8 PF09723.10 KIK35864.1 - 0.062 13.4 5.8 3.3 7.9 0.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 KIK35864.1 - 0.097 12.8 5.2 0.85 9.8 0.5 2.9 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.11 KIK35864.1 - 0.12 12.3 6.9 2.8 7.9 2.1 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DZR PF12773.7 KIK35864.1 - 0.13 12.3 3.1 8.3 6.5 0.1 2.6 2 0 0 2 2 2 0 Double zinc ribbon eIF-5_eIF-2B PF01873.17 KIK35864.1 - 0.43 10.5 6.5 5.8 6.8 0.4 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KIK35864.1 - 0.72 9.4 7.2 0.5 9.9 0.8 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.6 KIK35864.1 - 1.6 8.7 4.4 1.6 8.8 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KIK35864.1 - 2.8 7.5 5.4 4.7 6.8 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain HTH_Tnp_Mu_2 PF09039.11 KIK35868.1 - 0.0022 18.0 0.0 0.0026 17.8 0.0 1.1 1 0 0 1 1 1 1 Mu DNA binding, I gamma subdomain Rep_N PF08724.10 KIK35870.1 - 0.067 12.9 0.0 0.17 11.6 0.0 1.7 1 1 1 2 2 2 0 Rep protein catalytic domain like RT_RNaseH PF17917.1 KIK35871.1 - 2.5e-07 30.9 0.0 3.3e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KIK35871.1 - 0.0011 19.0 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 KIK35871.1 - 0.053 13.3 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase-like Integrase_H2C2 PF17921.1 KIK35872.1 - 8.6e-09 35.4 3.1 8.6e-09 35.4 3.1 1.4 2 0 0 2 2 2 1 Integrase zinc binding domain PGA2 PF07543.12 KIK35874.1 - 0.38 10.7 11.9 4.6 7.2 7.1 2.8 3 0 0 3 3 3 0 Protein trafficking PGA2 Laminin_I PF06008.14 KIK35877.1 - 0.0011 18.7 2.3 0.0016 18.2 2.3 1.1 1 0 0 1 1 1 1 Laminin Domain I Prominin PF05478.11 KIK35877.1 - 0.0025 15.9 2.9 0.003 15.6 2.9 1.0 1 0 0 1 1 1 1 Prominin T2SSM PF04612.12 KIK35877.1 - 0.0087 16.1 0.3 0.012 15.7 0.3 1.2 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M DUF2267 PF10025.9 KIK35877.1 - 0.016 15.5 0.4 0.027 14.7 0.4 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) DUF2408 PF10303.9 KIK35877.1 - 0.066 13.8 1.2 0.089 13.4 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Spectrin PF00435.21 KIK35877.1 - 0.07 13.6 1.6 0.33 11.5 1.3 2.0 1 1 1 2 2 2 0 Spectrin repeat DUF4795 PF16043.5 KIK35877.1 - 0.072 12.7 3.6 0.52 9.9 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) BST2 PF16716.5 KIK35877.1 - 0.081 13.5 4.9 11 6.6 3.1 2.4 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Nsp1_C PF05064.13 KIK35877.1 - 0.094 12.5 2.1 0.51 10.2 1.1 2.3 1 1 1 2 2 2 0 Nsp1-like C-terminal region Sec34 PF04136.15 KIK35877.1 - 0.1 12.5 4.5 0.28 11.1 4.4 1.6 1 1 0 1 1 1 0 Sec34-like family Jnk-SapK_ap_N PF09744.9 KIK35877.1 - 0.12 12.6 5.0 0.5 10.6 5.0 1.9 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Lyase_8_N PF08124.11 KIK35877.1 - 0.12 11.3 1.6 0.16 10.9 1.6 1.2 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain DUF2935 PF11155.8 KIK35877.1 - 0.23 11.8 2.7 9 6.7 0.6 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) DUF1664 PF07889.12 KIK35877.1 - 0.6 10.2 3.3 2.7 8.0 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Integrase_H2C2 PF17921.1 KIK35881.1 - 0.016 15.3 0.0 0.042 13.9 0.0 1.6 1 1 0 1 1 1 0 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 KIK35882.1 - 6.8e-06 26.1 0.0 7.4e-06 25.9 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TPR_1 PF00515.28 KIK35884.1 - 0.075 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat WD40 PF00400.32 KIK35887.1 - 3.3e-38 129.0 7.3 6.1e-06 26.9 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35887.1 - 1.5e-11 44.4 0.0 0.18 12.1 0.0 4.9 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK35887.1 - 0.00028 20.0 0.2 0.021 13.8 0.0 3.2 2 2 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Big_7 PF17957.1 KIK35887.1 - 0.0068 17.1 0.0 11 6.8 0.0 3.6 4 0 0 4 4 4 1 Bacterial Ig domain PD40 PF07676.12 KIK35887.1 - 0.018 15.0 0.1 20 5.2 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 KIK35887.1 - 0.022 13.5 0.0 0.1 11.3 0.0 2.0 2 0 0 2 2 2 0 Nup133 N terminal like ubiquitin PF00240.23 KIK35889.1 - 0.016 14.9 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family HicB_lk_antitox PF15919.5 KIK35890.1 - 0.028 14.6 0.0 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system ubiquitin PF00240.23 KIK35891.1 - 0.2 11.4 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family O-FucT PF10250.9 KIK35892.1 - 2.6e-11 43.8 0.0 1.1e-10 41.7 0.0 1.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase zf-C2H2 PF00096.26 KIK35894.1 - 1.2e-09 38.0 11.3 0.0019 18.6 1.8 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK35894.1 - 3e-09 36.9 9.5 1e-05 25.7 0.6 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 KIK35894.1 - 1.6e-08 34.1 7.5 0.00037 20.2 0.3 3.3 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KIK35894.1 - 7.2e-08 32.6 7.7 0.0036 18.0 1.0 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger IBR PF01485.21 KIK35894.1 - 0.0049 17.1 0.2 0.006 16.8 0.2 1.2 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain zf_C2H2_ZHX PF18387.1 KIK35894.1 - 0.02 14.5 0.4 0.97 9.1 0.1 2.3 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_aberr PF17017.5 KIK35894.1 - 0.024 14.8 0.9 0.024 14.8 0.9 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger Rep_fac-A_C PF08646.10 KIK35894.1 - 0.039 13.7 0.1 0.047 13.4 0.1 1.1 1 0 0 1 1 1 0 Replication factor-A C terminal domain OrsD PF12013.8 KIK35894.1 - 0.05 14.1 4.6 3.4 8.1 0.2 2.6 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D WD40 PF00400.32 KIK35898.1 - 2.1e-34 116.9 17.8 4e-07 30.6 0.0 6.1 5 1 1 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK35898.1 - 2e-11 44.1 0.0 0.0041 17.4 0.0 4.9 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK35898.1 - 5.6e-05 23.0 0.1 1.6 8.8 0.0 4.5 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KIK35898.1 - 0.00042 20.2 0.1 1.1 9.1 0.0 3.1 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK35898.1 - 0.0045 16.0 3.4 0.65 8.9 2.3 3.5 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KIK35898.1 - 0.01 14.6 0.0 0.19 10.4 0.0 2.1 1 1 0 2 2 2 0 Nup133 N terminal like Nup160 PF11715.8 KIK35898.1 - 0.015 13.9 0.1 0.11 11.2 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Big_7 PF17957.1 KIK35898.1 - 0.046 14.5 0.1 8.1 7.3 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig domain p450 PF00067.22 KIK35899.1 - 1.9e-39 135.7 0.0 2.6e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MPC PF03650.13 KIK35900.1 - 0.35 11.0 4.0 0.81 9.8 0.3 2.9 2 2 1 3 3 3 0 Mitochondrial pyruvate carriers UPF0242 PF06785.11 KIK35900.1 - 0.42 10.7 1.5 0.66 10.1 1.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PIG-P PF08510.12 KIK35900.1 - 0.55 10.2 4.9 1.4 8.9 1.1 2.3 1 1 1 2 2 2 0 PIG-P RdRP PF05183.12 KIK35901.1 - 2.6e-107 359.9 0.0 3.3e-107 359.6 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 KIK35902.1 - 2.4e-25 88.1 0.0 2.9e-13 49.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIK35902.1 - 1.1e-13 50.8 0.0 2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIK35902.1 - 1.2e-08 34.6 0.0 3e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KIK35902.1 - 0.0065 16.5 0.0 0.077 13.1 0.0 2.5 2 0 0 2 2 2 1 Limkain b1 PHM7_cyt PF14703.6 KIK35902.1 - 0.13 12.5 2.0 3.7 7.7 0.0 3.2 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 KIK35902.1 - 0.16 12.0 0.0 26 4.9 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif F-box PF00646.33 KIK35903.1 - 0.0014 18.5 0.7 0.0071 16.2 0.7 2.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK35903.1 - 0.0021 17.9 0.3 0.0082 16.0 0.3 2.1 1 0 0 1 1 1 1 F-box-like Malic_M PF03949.15 KIK35904.1 - 2.6e-83 279.3 0.0 4e-83 278.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KIK35904.1 - 9.3e-56 188.5 0.0 1.3e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Cwf_Cwc_15 PF04889.12 KIK35907.1 - 0.54 10.0 3.2 0.76 9.5 3.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Actin PF00022.19 KIK35908.1 - 6.3e-41 140.3 0.0 8.3e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Actin COX7B PF05392.11 KIK35908.1 - 0.13 12.0 0.0 13 5.6 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB UPRTase PF14681.6 KIK35909.1 - 1.7e-77 259.6 0.0 2.1e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KIK35909.1 - 0.00024 20.6 0.0 0.00035 20.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain EMG1 PF03587.14 KIK35912.1 - 7.2e-76 254.2 0.0 8.9e-76 253.9 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Ndc1_Nup PF09531.10 KIK35912.1 - 1.3 7.6 2.8 1.4 7.5 2.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 KIK35912.1 - 8.2 5.5 14.4 11 5.1 14.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CRAL_TRIO PF00650.20 KIK35913.1 - 6.7e-36 123.4 0.0 9.6e-36 122.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK35913.1 - 3.3e-09 36.8 0.1 8.6e-09 35.5 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain ATP-synt_E_2 PF08112.11 KIK35913.1 - 0.27 11.6 1.1 1 9.7 0.0 2.4 3 0 0 3 3 3 0 ATP synthase epsilon subunit F-box PF00646.33 KIK35914.1 - 0.0016 18.2 0.2 0.0043 16.9 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK35914.1 - 0.0023 17.8 0.1 0.0078 16.1 0.1 1.9 1 0 0 1 1 1 1 F-box-like p450 PF00067.22 KIK35915.1 - 1.1e-71 241.9 0.0 1.6e-71 241.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 COesterase PF00135.28 KIK35917.1 - 2.7e-77 260.8 0.9 3.9e-77 260.3 0.5 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK35917.1 - 1.3e-06 28.5 3.2 1.9e-05 24.6 2.5 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK35917.1 - 0.01 15.3 0.1 0.018 14.5 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DEAD PF00270.29 KIK35920.1 - 2.3e-17 63.3 0.0 4e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIK35920.1 - 4.2e-11 43.1 0.0 9.4e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIK35920.1 - 4.7e-05 23.7 0.0 0.00011 22.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain KIF1B PF12423.8 KIK35920.1 - 1.2 9.6 3.9 3.8 8.0 3.9 1.9 1 0 0 1 1 1 0 Kinesin protein 1B CHAT PF12770.7 KIK35922.1 - 1.8e-31 109.7 0.0 3.7e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK35922.1 - 3e-12 46.0 10.0 0.014 15.2 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIK35922.1 - 5.3e-08 33.1 6.8 0.0011 19.3 0.6 6.5 3 2 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK35922.1 - 9.1e-07 28.5 2.3 5.1 7.3 0.0 5.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK35922.1 - 0.0017 18.3 2.7 32 5.0 0.0 6.2 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK35922.1 - 0.0053 16.4 0.1 34 4.2 0.0 5.2 4 0 0 4 4 4 0 TPR repeat TPR_1 PF00515.28 KIK35922.1 - 0.008 16.0 4.8 29 4.7 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat C2 PF00168.30 KIK35922.1 - 0.094 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 C2 domain MIT PF04212.18 KIK35922.1 - 0.14 12.3 0.4 83 3.4 0.0 4.7 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Aldo_ket_red PF00248.21 KIK35923.1 - 1.9e-43 148.7 0.0 1.3e-41 142.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Ribosomal_S6e PF01092.19 KIK35924.1 - 8e-56 187.4 0.0 1.6e-55 186.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e MKLP1_Arf_bdg PF16540.5 KIK35924.1 - 0.2 11.7 3.8 0.34 11.0 1.9 2.1 2 0 0 2 2 2 0 Arf6-interacting domain of mitotic kinesin-like protein 1 Ribosomal_S13_N PF08069.12 KIK35925.1 - 2.1e-31 107.8 0.2 4.2e-31 106.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KIK35925.1 - 4.2e-15 55.7 0.4 5.4e-15 55.4 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KIK35925.1 - 0.046 13.7 0.0 0.099 12.6 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain DUF5061 PF16587.5 KIK35926.1 - 0.0033 17.5 1.4 0.24 11.5 0.1 2.2 2 0 0 2 2 2 2 17 kDa common-antigen outer membrane protein DUF2489 PF10675.9 KIK35926.1 - 2.4 8.1 7.8 15 5.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) APH PF01636.23 KIK35927.1 - 7.9e-13 48.9 0.0 2.3e-12 47.4 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF5442 PF17514.2 KIK35927.1 - 0.16 12.2 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5442) HET-S PF17108.5 KIK35928.1 - 3.1e-05 23.6 7.3 21 4.9 0.1 6.7 7 0 0 7 7 7 1 N-terminal small S protein of HET, non-prionic Exop_C PF18559.1 KIK35928.1 - 0.0015 18.4 0.7 0.35 10.7 0.1 2.1 1 1 1 2 2 2 2 Galactose-binding domain-like zf-NOSIP PF15906.5 KIK35928.1 - 0.15 12.2 0.0 30 4.8 0.0 2.8 1 1 2 3 3 3 0 Zinc-finger of nitric oxide synthase-interacting protein DUF2807 PF10988.8 KIK35928.1 - 0.16 11.7 0.6 0.19 11.5 0.6 1.1 1 0 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain DUF1424 PF07232.11 KIK35929.1 - 0.012 14.6 0.1 0.013 14.5 0.1 1.1 1 0 0 1 1 1 0 Putative rep protein (DUF1424) Cep57_MT_bd PF06657.13 KIK35929.1 - 0.035 14.6 0.1 0.072 13.5 0.1 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 CBM_21 PF03370.13 KIK35933.1 - 1.6e-20 73.4 0.0 2.7e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KIK35933.1 - 1.3e-06 28.8 0.3 5.4e-06 26.9 0.3 1.9 1 1 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) TPR_10 PF13374.6 KIK35938.1 - 2.1e-08 33.8 10.9 0.00036 20.3 0.0 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK35938.1 - 9.9e-08 32.2 2.2 0.085 13.2 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK35938.1 - 5e-05 23.1 2.9 0.072 13.2 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK35938.1 - 0.00045 20.8 0.6 0.09 13.6 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK35938.1 - 0.00079 19.4 0.0 3.1 8.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK35938.1 - 0.0035 17.0 0.4 0.36 10.6 0.0 3.1 3 0 0 3 3 3 1 TPR repeat RFamide_26RFa PF11109.8 KIK35938.1 - 0.016 15.7 0.1 12 6.4 0.0 2.8 2 1 0 3 3 3 0 Orexigenic neuropeptide Qrfp/P518 DUF2778 PF10908.8 KIK35938.1 - 0.018 15.3 0.2 2.2 8.6 0.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2778) GATase_4 PF13230.6 KIK35938.1 - 0.037 12.9 0.0 0.099 11.5 0.0 1.7 1 1 1 2 2 2 0 Glutamine amidotransferases class-II TPR_16 PF13432.6 KIK35938.1 - 0.047 14.4 4.4 0.29 11.8 1.7 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK35938.1 - 0.12 12.2 0.1 0.12 12.2 0.1 3.8 6 0 0 6 6 6 0 Tetratricopeptide repeat CHAT PF12770.7 KIK35939.1 - 2.7e-38 132.1 0.0 4.1e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 CHAT domain Peptidase_M17 PF00883.21 KIK35941.1 - 5.2e-60 203.3 0.0 5.8e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain MFS_1 PF07690.16 KIK35942.1 - 5.5e-43 147.2 42.8 5.5e-43 147.2 42.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK35942.1 - 6e-07 28.7 0.9 6e-07 28.7 0.9 3.7 3 1 1 4 4 4 2 Sugar (and other) transporter DUF4514 PF14986.6 KIK35942.1 - 0.22 11.5 2.3 1 9.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) Cas_Cas02710 PF09670.10 KIK35944.1 - 0.041 12.7 0.0 0.045 12.6 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) MGC-24 PF05283.11 KIK35947.1 - 0.26 11.7 6.4 0.4 11.1 6.4 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SprA-related PF12118.8 KIK35947.1 - 2.1 7.4 8.9 2.7 7.0 8.9 1.1 1 0 0 1 1 1 0 SprA-related family ATF7IP_BD PF16788.5 KIK35947.1 - 4.1 7.4 6.6 4.9 7.2 6.6 1.1 1 0 0 1 1 1 0 ATF-interacting protein binding domain MSP1_C PF07462.11 KIK35947.1 - 5.7 5.5 6.3 5.9 5.5 6.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Sporozoite_P67 PF05642.11 KIK35947.1 - 7.3 4.5 13.7 8.6 4.3 13.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 KIK35948.1 - 0.044 13.1 0.4 0.066 12.5 0.4 1.3 1 0 0 1 1 1 0 NOA36 protein Abhydrolase_1 PF00561.20 KIK35950.1 - 1.1e-17 64.6 0.1 1.6e-17 64.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK35950.1 - 1.2e-12 48.9 0.6 2.1e-12 48.2 0.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK35950.1 - 9.6e-06 25.0 0.0 1.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KIK35950.1 - 5e-05 22.1 0.0 7.3e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family Cauli_VI PF01693.16 KIK35955.1 - 2.1e-12 47.1 0.0 4.6e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF5608 PF18356.1 KIK35955.1 - 0.21 11.6 0.0 0.45 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5608) DASH_Duo1 PF08651.10 KIK35957.1 - 5.2e-18 64.6 0.2 7.5e-18 64.1 0.2 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 WXG100 PF06013.12 KIK35957.1 - 0.11 12.7 3.3 0.22 11.8 0.6 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG GPI-anchored PF10342.9 KIK35958.1 - 6e-09 36.5 0.7 7.6e-09 36.2 0.7 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KIK35958.1 - 0.00035 20.4 0.0 0.00041 20.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) NPCBM_assoc PF10633.9 KIK35958.1 - 0.086 13.1 1.5 0.21 11.9 0.0 2.0 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DEAD PF00270.29 KIK35959.1 - 4.7e-39 134.0 0.0 1.6e-38 132.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK35959.1 - 2.3e-22 79.4 0.0 7.8e-22 77.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KIK35959.1 - 1.9e-18 66.4 3.2 8.2e-18 64.4 3.2 2.2 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.15 KIK35959.1 - 0.00016 21.7 0.0 0.00038 20.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TGT PF01702.18 KIK35960.1 - 6.6e-128 426.8 0.0 7.9e-128 426.5 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase tRNA-synt_1b PF00579.25 KIK35961.1 - 1.2e-73 248.0 0.0 1.7e-73 247.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TPR_10 PF13374.6 KIK35966.1 - 4.8e-16 58.0 9.0 0.0001 22.0 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK35966.1 - 9e-08 32.3 8.6 0.19 12.1 0.4 4.1 1 1 2 3 3 3 3 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 KIK35966.1 - 8.8e-05 22.5 2.1 14 5.8 0.0 4.2 4 0 0 4 4 4 0 Exonuclease VII small subunit NRBF2_MIT PF17169.4 KIK35966.1 - 0.0006 20.0 1.5 7.5 6.8 0.1 3.7 4 0 0 4 4 4 2 MIT domain of nuclear receptor-binding factor 2 TPR_11 PF13414.6 KIK35966.1 - 0.0018 17.9 2.7 11 5.8 0.0 4.2 4 0 0 4 4 4 1 TPR repeat TPR_7 PF13176.6 KIK35966.1 - 0.0019 18.1 6.8 14 5.9 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TrbM PF07424.11 KIK35966.1 - 0.0047 16.9 0.0 0.65 9.9 0.0 2.1 1 1 1 2 2 2 2 TrbM TPR_14 PF13428.6 KIK35966.1 - 0.006 17.3 4.4 11 7.2 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat GATase_4 PF13230.6 KIK35966.1 - 0.0065 15.4 0.1 0.51 9.2 0.0 2.0 1 1 1 2 2 2 2 Glutamine amidotransferases class-II Fer4_13 PF13370.6 KIK35966.1 - 0.041 14.4 0.0 12 6.5 0.0 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I DUF4471 PF14740.6 KIK35966.1 - 0.063 12.5 0.0 6.9 5.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4471) FdsD PF11390.8 KIK35966.1 - 0.11 12.9 0.1 6.9 7.1 0.1 2.4 2 0 0 2 2 2 0 NADH-dependant formate dehydrogenase delta subunit FdsD TPR_1 PF00515.28 KIK35966.1 - 0.2 11.5 9.8 33 4.5 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK35966.1 - 8.8 6.7 7.1 1.4e+02 2.9 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIK35967.1 - 0.00016 21.9 0.3 0.042 14.1 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK35967.1 - 0.005 16.9 0.0 0.76 10.0 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK35967.1 - 0.012 16.4 0.3 1.6 9.8 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK35967.1 - 0.019 14.8 0.1 1.8 8.5 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK35967.1 - 0.038 13.7 0.0 0.72 9.6 0.0 2.9 3 1 0 3 3 3 0 TPR repeat DUF2989 PF11207.8 KIK35967.1 - 0.068 12.9 0.0 8.1 6.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2989) TPR_8 PF13181.6 KIK35967.1 - 0.07 13.4 0.0 6.5 7.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CCDC106 PF15794.5 KIK35969.1 - 1.3 8.6 8.3 1.4 8.5 8.3 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SR-25 PF10500.9 KIK35969.1 - 1.6 8.3 15.9 1.9 8.1 15.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HLH PF00010.26 KIK35976.1 - 6.6e-17 61.2 0.0 4.4e-16 58.6 0.0 2.4 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain MFS_1 PF07690.16 KIK35978.1 - 3e-10 39.5 34.1 3e-10 39.5 34.1 1.5 1 1 0 2 2 2 1 Major Facilitator Superfamily SlyX PF04102.12 KIK35979.1 - 0.0072 16.9 2.1 0.15 12.7 0.5 2.7 1 1 1 2 2 2 1 SlyX Sec23_helical PF04815.15 KIK35979.1 - 0.013 15.3 0.1 0.031 14.1 0.1 1.6 1 0 0 1 1 1 0 Sec23/Sec24 helical domain Baculo_PEP_C PF04513.12 KIK35979.1 - 0.33 11.0 3.0 1.4 9.0 0.2 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_L30 PF00327.20 KIK35981.1 - 3.8e-11 42.7 0.2 6e-11 42.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Abhydrolase_6 PF12697.7 KIK35982.1 - 9.7e-21 75.4 1.2 1.5e-20 74.8 1.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK35982.1 - 4.4e-09 36.0 0.2 6.5e-09 35.4 0.2 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KIK35982.1 - 6.7e-07 29.7 0.0 9.3e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 KIK35982.1 - 0.0044 16.7 0.0 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 KIK35982.1 - 0.005 16.4 0.0 0.0072 15.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 KIK35982.1 - 0.012 15.3 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.7 KIK35982.1 - 0.026 13.4 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme GP3_package PF16677.5 KIK35985.1 - 0.0058 16.8 0.4 0.054 13.6 0.2 2.0 1 1 1 2 2 2 1 DNA-packaging protein gp3 DUF3232 PF11554.8 KIK35985.1 - 0.021 15.2 0.6 0.065 13.6 0.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3232) COG5 PF10392.9 KIK35985.1 - 0.035 14.3 0.1 0.054 13.7 0.1 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Cauli_VI PF01693.16 KIK35986.1 - 6.5e-07 29.6 0.0 1.3e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin PH_2 PF08458.10 KIK35986.1 - 0.076 13.4 0.0 0.08 13.3 0.0 1.1 1 0 0 1 1 1 0 Plant pleckstrin homology-like region KDZ PF18758.1 KIK35987.1 - 1.2e-64 218.0 0.0 2.1e-64 217.2 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK35987.1 - 5.3e-44 148.8 0.0 2.4e-43 146.7 0.0 2.0 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK35987.1 - 4.7e-06 26.7 0.0 1.3e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases ZZ PF00569.17 KIK35987.1 - 3.6 7.5 8.8 7.7 6.4 8.8 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type Pkinase_fungal PF17667.1 KIK35988.1 - 6.1e-37 127.4 0.0 5.2e-23 81.5 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIK35988.1 - 2.6e-06 27.0 0.0 4.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK35988.1 - 0.1 12.5 0.2 0.27 11.1 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family NESP55 PF06390.12 KIK35988.1 - 1.6 8.3 3.6 2.7 7.5 3.6 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) KOW PF00467.29 KIK35989.1 - 3.4e-08 33.2 14.9 0.058 13.4 1.6 6.5 5 2 0 5 5 5 3 KOW motif Spt5_N PF11942.8 KIK35989.1 - 0.01 16.8 1.7 0.023 15.7 1.7 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CPSase_L_D2 PF02786.17 KIK35990.1 - 5.2e-06 26.1 0.0 7.4e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain DUF1433 PF07252.11 KIK35990.1 - 0.02 15.1 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1433) Dala_Dala_lig_C PF07478.13 KIK35990.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Pkinase PF00069.25 KIK35991.1 - 3.1e-13 49.7 0.1 4.5e-10 39.3 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK35991.1 - 4.1e-05 23.0 0.2 0.021 14.1 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Transposase_21 PF02992.14 KIK35994.1 - 1.4e-05 24.5 0.0 2.8e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Transposase family tnp2 Plavaka PF18759.1 KIK35994.1 - 0.0042 16.4 0.0 0.0057 15.9 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase DUF4218 PF13960.6 KIK35995.1 - 2.8e-06 26.9 0.5 7.5e-06 25.5 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) NuDC PF16273.5 KIK35995.1 - 0.14 12.7 0.1 0.25 11.9 0.1 1.4 1 0 0 1 1 1 0 Nuclear distribution C domain CBFD_NFYB_HMF PF00808.23 KIK35996.1 - 0.0074 16.5 0.0 0.028 14.7 0.0 2.0 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Adeno_GP19K PF04881.13 KIK36004.1 - 0.088 12.8 0.4 0.13 12.2 0.1 1.4 1 1 0 1 1 1 0 Adenovirus GP19K Polysacc_synt_C PF14667.6 KIK36004.1 - 0.25 11.4 4.2 0.32 11.0 3.6 1.5 1 1 1 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Hydrolase_like PF13242.6 KIK36006.1 - 8.6e-06 25.7 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 KIK36006.1 - 1.6e-05 25.0 0.0 2.3e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK36006.1 - 0.00038 20.8 0.0 0.0011 19.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-4CXXC_R1 PF10497.9 KIK36007.1 - 0.0083 16.3 8.8 0.011 15.9 8.8 1.1 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 US6 PF17616.2 KIK36007.1 - 0.015 15.3 0.5 0.016 15.2 0.5 1.0 1 0 0 1 1 1 0 Viral unique short region 6 DUF3684 PF12449.8 KIK36008.1 - 2.2e-64 217.8 0.0 2.7e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 KIK36008.1 - 0.0023 17.8 0.1 0.013 15.3 0.1 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Aldo_ket_red PF00248.21 KIK36009.1 - 2.3e-66 224.0 0.0 2.7e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KIK36010.1 - 3.1e-62 210.4 0.0 3.9e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PalH PF08733.10 KIK36011.1 - 0.64 9.0 16.3 4.7 6.1 16.3 1.9 1 1 0 1 1 1 0 PalH/RIM21 VIT1 PF01988.19 KIK36011.1 - 4.7 7.0 9.7 0.7 9.7 2.2 2.3 2 0 0 2 2 2 0 VIT family iPGM_N PF06415.13 KIK36012.1 - 2.8e-75 252.5 0.0 4.3e-75 251.9 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KIK36012.1 - 4.9e-75 252.1 0.6 5.7e-75 251.9 0.6 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KIK36012.1 - 8e-06 25.5 0.1 0.0001 21.9 0.1 2.3 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KIK36012.1 - 0.00085 19.0 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.12 KIK36012.1 - 0.00093 19.3 0.0 0.0026 17.9 0.0 1.7 2 0 0 2 2 2 1 PglZ domain Alk_phosphatase PF00245.20 KIK36012.1 - 0.013 14.5 0.7 0.059 12.3 0.3 2.0 2 0 0 2 2 2 0 Alkaline phosphatase AP_endonuc_2 PF01261.24 KIK36012.1 - 0.05 13.0 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF2292 PF10055.9 KIK36012.1 - 0.14 11.8 0.1 1.4 8.6 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2292) HLH PF00010.26 KIK36013.1 - 0.038 13.9 2.3 0.063 13.3 2.3 1.4 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain SdpA PF17418.2 KIK36013.1 - 0.096 12.5 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Sporulation delaying protein SdpA Limkain-b1 PF11608.8 KIK36014.1 - 0.11 12.5 0.2 0.17 12.0 0.2 1.2 1 0 0 1 1 1 0 Limkain b1 La PF05383.17 KIK36018.1 - 1.7e-08 34.4 0.0 2.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 La domain Pmp3 PF01679.17 KIK36019.1 - 8.5e-25 86.7 11.1 1.1e-24 86.3 11.1 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TPPK_C PF12555.8 KIK36019.1 - 0.11 12.5 0.9 0.16 12.0 0.9 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal MFS_1 PF07690.16 KIK36021.1 - 1.1e-21 77.2 38.6 1.5e-21 76.7 38.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4667 PF15700.5 KIK36022.1 - 0.076 13.1 2.5 0.12 12.5 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) Barwin PF00967.17 KIK36022.1 - 0.82 9.5 3.4 22 4.9 1.3 3.1 2 1 0 2 2 2 0 Barwin family MFS_1 PF07690.16 KIK36023.1 - 1.3e-25 90.1 41.0 1.3e-25 90.1 41.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily rve PF00665.26 KIK36026.1 - 4.9e-05 23.5 0.0 9.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 KIK36027.1 - 1.8e-07 31.1 0.0 2e-07 31.0 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KIK36027.1 - 0.13 12.5 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Antimicrobial17 PF08129.11 KIK36029.1 - 0.33 11.0 1.2 0.6 10.1 0.2 1.9 2 0 0 2 2 2 0 Alpha/beta enterocin family Plavaka PF18759.1 KIK36032.1 - 3.9e-05 23.1 1.0 6.3e-05 22.3 1.0 1.3 1 0 0 1 1 1 1 Plavaka transposase KDZ PF18758.1 KIK36033.1 - 6.5e-62 209.1 0.1 1e-61 208.4 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK36033.1 - 2.9e-43 146.4 0.1 6.4e-43 145.3 0.1 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK36033.1 - 0.00052 20.1 0.1 0.00052 20.1 0.1 1.9 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK36033.1 - 0.0078 16.0 2.9 0.015 15.1 0.1 2.7 2 1 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases Retrotran_gag_3 PF14244.6 KIK36034.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type MFS_1 PF07690.16 KIK36042.1 - 8.1e-32 110.5 53.9 4.5e-28 98.2 27.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK36042.1 - 0.00042 19.3 5.1 0.00042 19.3 5.1 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter SPT2 PF08243.11 KIK36043.1 - 1.3e-20 73.9 4.8 1.3e-20 73.9 4.8 4.2 3 1 1 4 4 4 1 SPT2 chromatin protein RRM_1 PF00076.22 KIK36044.1 - 1.7e-06 27.7 0.0 3.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPA PF08616.10 KIK36045.1 - 1.4e-08 34.7 0.0 2.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis CysG_dimeriser PF10414.9 KIK36045.1 - 0.016 14.9 0.5 0.031 14.0 0.5 1.5 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region Hexapep_loop PF18776.1 KIK36045.1 - 0.14 11.8 0.2 0.36 10.5 0.2 1.7 1 0 0 1 1 1 0 Hexapeptide repeat including loop Piwi PF02171.17 KIK36046.1 - 2.8e-69 233.6 0.0 3.4e-68 230.1 0.0 2.1 2 0 0 2 2 2 1 Piwi domain ArgoL1 PF08699.10 KIK36046.1 - 1.4e-14 53.5 0.2 3.7e-14 52.1 0.2 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KIK36046.1 - 5.9e-06 26.5 0.5 3.2e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 Argonaute linker 2 domain PAZ PF02170.22 KIK36046.1 - 8.8e-06 25.6 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 KIK36046.1 - 1.6e-05 25.5 0.0 3.9e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoMid PF16487.5 KIK36046.1 - 0.0003 21.0 0.4 0.0067 16.7 0.1 2.5 2 0 0 2 2 2 1 Mid domain of argonaute F-box-like PF12937.7 KIK36048.1 - 1.9e-07 30.8 10.3 1.1e-06 28.5 10.3 2.3 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK36048.1 - 0.0038 17.1 7.8 0.049 13.5 0.2 3.7 4 0 0 4 4 4 1 F-box domain Vac17 PF17321.2 KIK36048.1 - 0.066 12.6 0.1 0.078 12.4 0.1 1.1 1 0 0 1 1 1 0 Vacuole-related protein 17 CID_GANP PF16766.5 KIK36049.1 - 0.049 13.8 1.0 0.089 13.0 1.0 1.4 1 0 0 1 1 1 0 Binding region of GANP to ENY2 DUF4241 PF14025.6 KIK36053.1 - 0.09 13.1 0.0 0.093 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) DHHA2 PF02833.14 KIK36055.1 - 3.6e-14 53.1 0.0 4.8e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 DHHA2 domain CHAT PF12770.7 KIK36061.1 - 2.7e-30 105.8 0.0 5.4e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK36061.1 - 8.8e-11 41.3 2.6 0.026 14.4 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat MIT PF04212.18 KIK36061.1 - 1.5e-08 34.5 0.1 0.054 13.6 0.0 5.0 4 1 1 5 5 5 2 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 KIK36061.1 - 1.8e-06 28.2 6.2 0.52 10.6 0.0 6.2 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK36061.1 - 2.3e-06 27.2 4.4 9.8 6.2 0.1 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK36061.1 - 3.2e-06 26.8 0.0 4.1 7.7 0.0 6.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK36061.1 - 6.6e-06 25.8 7.9 16 5.9 0.0 7.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK36061.1 - 0.017 15.3 1.1 1e+02 3.5 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK36061.1 - 0.041 13.6 0.2 43 3.9 0.0 4.5 4 0 0 4 4 4 0 TPR repeat TPR_14 PF13428.6 KIK36061.1 - 0.25 12.3 15.7 87 4.4 0.0 8.6 10 1 1 11 11 10 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KIK36061.1 - 0.95 9.0 4.0 26 4.4 0.2 4.5 4 0 0 4 4 4 0 SHNi-TPR Vta1_C PF18097.1 KIK36061.1 - 2 8.2 6.1 4.6 7.0 0.0 4.0 4 0 0 4 4 4 0 Vta1 C-terminal domain UPF0220 PF05255.11 KIK36062.1 - 1.2e-55 187.5 0.0 1.5e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) HMG_box PF00505.19 KIK36063.1 - 2.2e-09 37.6 11.1 3.1e-08 33.9 11.1 2.2 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK36063.1 - 1.9e-07 31.6 10.7 4.6e-07 30.3 10.7 1.6 1 1 0 1 1 1 1 HMG-box domain WD40 PF00400.32 KIK36064.1 - 1.5e-12 47.8 11.1 0.00013 22.7 0.8 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36064.1 - 2.2e-05 24.7 0.0 0.043 14.1 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 KIK36064.1 - 0.064 13.2 0.0 35 4.4 0.0 3.5 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal DUF1961 PF09224.11 KIK36064.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) Dynamin_M PF01031.20 KIK36065.1 - 1.1e-28 100.3 0.0 2.8e-28 98.9 0.0 1.6 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KIK36065.1 - 8.8e-27 94.2 0.0 2.3e-26 92.9 0.0 1.7 1 1 0 1 1 1 1 Dynamin family GED PF02212.18 KIK36065.1 - 3.3e-09 36.8 0.7 8.3e-09 35.5 0.1 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIK36065.1 - 0.00017 21.6 0.7 0.0033 17.5 0.7 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KIK36065.1 - 0.0026 18.2 0.2 0.15 12.4 0.0 3.2 3 1 0 3 3 3 1 AAA ATPase domain AAA_28 PF13521.6 KIK36065.1 - 0.043 14.1 0.7 0.17 12.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain Ceramidase_alk PF04734.13 KIK36069.1 - 3.2e-212 705.7 0.0 3.7e-212 705.5 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KIK36069.1 - 3.9e-58 196.0 0.2 7.5e-58 195.1 0.2 1.5 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal MG2 PF01835.19 KIK36069.1 - 0.024 15.1 0.2 0.08 13.4 0.2 1.8 1 1 0 1 1 1 0 MG2 domain DUF1479 PF07350.12 KIK36070.1 - 1.1e-127 426.3 0.0 1.3e-127 426.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Dynamin_N PF00350.23 KIK36073.1 - 8.6e-29 100.7 0.0 3.1e-28 98.9 0.0 2.0 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KIK36073.1 - 1.4e-23 83.5 0.4 1.2e-17 64.0 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 KIK36073.1 - 5.3e-12 45.7 0.1 2.7e-11 43.4 0.0 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIK36073.1 - 8.2e-05 22.7 0.0 0.00084 19.4 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase UPF0449 PF15136.6 KIK36073.1 - 0.0058 17.1 3.0 0.22 12.0 0.1 3.2 3 0 0 3 3 3 1 Uncharacterised protein family UPF0449 AAA_16 PF13191.6 KIK36073.1 - 0.025 15.0 0.1 0.34 11.3 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 KIK36073.1 - 0.031 14.0 0.1 0.071 12.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KIK36073.1 - 0.083 13.4 0.3 0.29 11.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Merozoite_SPAM PF07133.11 KIK36074.1 - 0.37 10.8 15.4 0.81 9.7 15.4 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) TFIIF_alpha PF05793.12 KIK36074.1 - 0.53 8.8 10.4 1.1 7.8 10.4 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-TFIIIC PF12660.7 KIK36074.1 - 1 9.4 3.2 2.4 8.2 0.8 2.5 3 0 0 3 3 3 0 Putative zinc-finger of transcription factor IIIC complex RNA_pol_L_2 PF13656.6 KIK36075.1 - 5.3e-29 99.8 0.0 6.1e-29 99.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KIK36075.1 - 8.9e-09 34.7 0.0 1.1e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RicinB_lectin_2 PF14200.6 KIK36078.1 - 0.019 15.7 0.0 0.019 15.7 0.0 1.0 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIK36078.1 - 0.051 13.8 0.0 0.057 13.7 0.0 1.0 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain WD40 PF00400.32 KIK36082.1 - 1.2e-27 95.6 9.7 6.2e-08 33.2 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36082.1 - 3.9e-11 43.1 1.7 0.0029 17.9 0.0 4.2 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK36082.1 - 3.4e-06 26.0 0.7 0.021 13.5 0.0 3.0 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK36082.1 - 0.0003 19.9 0.0 0.23 10.4 0.0 2.5 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK36082.1 - 0.0077 15.6 0.0 1 8.6 0.0 2.8 3 0 0 3 3 3 1 WD40-like domain Ret2_MD PF18528.1 KIK36082.1 - 0.015 15.7 0.0 0.044 14.1 0.0 1.8 1 0 0 1 1 1 0 RNA editing 3' terminal uridylyl transferase 2 middle domain DUF1513 PF07433.11 KIK36082.1 - 0.045 12.8 0.0 8.1 5.4 0.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1513) WD40 PF00400.32 KIK36085.1 - 6.2e-17 61.7 5.3 2e-08 34.7 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36085.1 - 6.2e-05 23.2 0.0 0.14 12.5 0.0 2.2 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK36085.1 - 0.0048 15.6 0.2 0.0057 15.4 0.2 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK36085.1 - 0.037 13.0 0.0 0.29 10.1 0.0 2.0 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KIK36086.1 - 1.6e-28 98.3 9.2 1.7e-08 34.9 0.9 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36086.1 - 2.3e-10 40.6 0.1 0.0044 17.3 0.0 3.7 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK36086.1 - 0.00013 20.8 1.7 0.0055 15.4 0.0 2.9 3 0 0 3 3 3 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK36086.1 - 0.00053 19.4 0.0 0.35 10.2 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 KIK36086.1 - 0.053 12.5 0.0 2.4 7.0 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribonuc_red_2_N PF08471.10 KIK36087.1 - 0.053 13.7 0.0 0.057 13.6 0.0 1.0 1 0 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase AAA_16 PF13191.6 KIK36088.1 - 0.00011 22.6 0.0 0.00014 22.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK36088.1 - 0.001 19.0 0.5 0.0019 18.1 0.1 1.6 2 0 0 2 2 2 1 NACHT domain APS_kinase PF01583.20 KIK36088.1 - 0.0023 17.8 0.1 0.0037 17.2 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase NB-ARC PF00931.22 KIK36088.1 - 0.0048 16.1 0.0 0.0058 15.8 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 KIK36088.1 - 0.0049 17.4 0.9 0.06 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KIK36088.1 - 0.02 14.6 0.0 0.024 14.4 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain RuvB_N PF05496.12 KIK36088.1 - 0.02 14.6 0.0 0.024 14.4 0.0 1.1 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 KIK36088.1 - 0.022 14.7 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 KIK36088.1 - 0.023 14.4 0.0 0.024 14.4 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein ResIII PF04851.15 KIK36088.1 - 0.028 14.4 0.0 0.028 14.4 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF815 PF05673.13 KIK36088.1 - 0.03 13.5 0.0 0.033 13.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA PF00004.29 KIK36088.1 - 0.031 14.7 0.0 0.051 14.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK36088.1 - 0.048 14.0 0.0 0.078 13.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KIK36088.1 - 0.051 13.1 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KIK36088.1 - 0.062 13.8 0.1 0.12 12.9 0.1 1.4 1 1 0 1 1 1 0 ABC transporter TsaE PF02367.17 KIK36088.1 - 0.09 12.8 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KIK36088.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KIK36088.1 - 0.14 11.2 0.0 0.15 11.1 0.0 1.0 1 0 0 1 1 1 0 Type II/IV secretion system protein ParA PF10609.9 KIK36088.1 - 0.17 11.3 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase WD40 PF00400.32 KIK36089.1 - 2.1e-25 88.4 5.1 9.8e-09 35.7 0.1 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36089.1 - 1.4e-09 38.1 0.2 0.039 14.2 0.0 4.0 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK36089.1 - 0.00043 19.1 0.0 0.001 17.8 0.0 1.7 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK36089.1 - 0.0026 16.8 0.0 0.41 9.6 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK36089.1 - 0.0042 16.5 0.0 0.3 10.4 0.0 2.8 2 2 1 3 3 3 1 WD40-like domain PhzC-PhzF PF02567.16 KIK36090.1 - 2.2e-17 63.4 0.0 2.5e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pkinase_Tyr PF07714.17 KIK36091.1 - 1.7e-40 138.9 0.0 2.4e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK36091.1 - 2.5e-36 125.4 0.0 4e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain MMR_HSR1 PF01926.23 KIK36091.1 - 1.3e-06 28.5 0.0 7.7e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK36091.1 - 9.6e-05 21.8 0.0 0.00026 20.4 0.0 1.7 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KIK36091.1 - 0.00081 19.3 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Kdo PF06293.14 KIK36091.1 - 0.0012 18.2 0.5 0.013 14.9 0.0 2.6 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Roc PF08477.13 KIK36091.1 - 0.0054 16.9 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KIK36091.1 - 0.0059 17.0 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 KIK36091.1 - 0.013 15.5 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Dynamin family ABC_tran PF00005.27 KIK36091.1 - 0.014 15.9 0.0 0.037 14.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KIK36091.1 - 0.029 14.6 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK36091.1 - 0.076 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 KIK36091.1 - 0.099 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Septin PF00735.18 KIK36091.1 - 0.15 11.3 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Septin WD40 PF00400.32 KIK36092.1 - 2.9e-19 69.0 18.2 3.8e-07 30.7 2.2 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36092.1 - 2.9e-17 62.7 1.6 0.00016 21.9 0.1 5.9 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KIK36092.1 - 2.1e-05 24.0 0.5 0.0025 17.2 0.1 3.1 2 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK36092.1 - 3.7e-05 22.6 0.8 0.17 10.5 0.0 3.6 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK36092.1 - 0.00016 20.8 0.0 0.017 14.1 0.0 3.0 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK36092.1 - 0.001 19.0 0.6 53 3.9 0.0 5.7 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat PQQ PF01011.21 KIK36092.1 - 0.0026 17.6 0.1 0.48 10.4 0.0 3.9 4 0 0 4 4 4 1 PQQ enzyme repeat zf-H2C2_5 PF13909.6 KIK36093.1 - 4e-09 36.1 12.9 0.00033 20.4 1.1 3.2 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIK36093.1 - 2.1e-07 31.0 17.2 0.0022 18.3 4.5 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK36093.1 - 5.8e-06 26.7 13.5 0.05 14.5 2.9 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK36093.1 - 5.4e-05 23.4 1.3 5.4e-05 23.4 1.3 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 KIK36093.1 - 0.01 15.5 3.1 1.9 8.2 0.1 2.3 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Omega-toxin PF06357.11 KIK36093.1 - 0.011 15.5 4.5 1.5 8.6 0.4 2.7 2 1 0 2 2 2 0 Omega-atracotoxin IBR PF01485.21 KIK36093.1 - 0.021 15.0 1.8 0.021 15.0 1.8 1.5 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain DUF1390 PF07150.11 KIK36093.1 - 7.8 6.1 7.8 12 5.5 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1390) TPR_16 PF13432.6 KIK36095.1 - 1.7e-40 137.4 56.2 6.2e-11 42.8 4.4 12.6 13 1 3 16 16 13 10 Tetratricopeptide repeat TPR_1 PF00515.28 KIK36095.1 - 3.4e-38 127.9 19.9 1.1e-05 25.0 0.0 14.6 14 0 0 14 14 13 7 Tetratricopeptide repeat TPR_2 PF07719.17 KIK36095.1 - 1.1e-34 115.7 39.0 0.0015 18.5 0.2 17.8 20 0 0 20 20 19 7 Tetratricopeptide repeat TPR_8 PF13181.6 KIK36095.1 - 3.6e-29 98.5 15.2 0.00041 20.3 0.1 15.4 16 0 0 16 16 14 4 Tetratricopeptide repeat TPR_19 PF14559.6 KIK36095.1 - 2.3e-28 98.5 42.8 2.3e-05 24.8 0.5 11.6 11 1 1 12 12 12 9 Tetratricopeptide repeat TPR_14 PF13428.6 KIK36095.1 - 2.3e-22 77.7 62.7 0.0022 18.6 0.5 19.7 13 7 9 22 22 22 6 Tetratricopeptide repeat TPR_17 PF13431.6 KIK36095.1 - 3.6e-20 70.8 13.2 0.012 15.9 0.1 13.9 14 0 0 14 14 13 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK36095.1 - 3.9e-15 55.9 52.2 0.0022 18.2 2.3 14.0 11 4 5 16 16 16 5 Tetratricopeptide repeat TPR_11 PF13414.6 KIK36095.1 - 1.5e-14 53.3 28.8 0.0013 18.4 0.5 12.7 12 3 3 15 15 14 4 TPR repeat TPR_6 PF13174.6 KIK36095.1 - 3e-14 52.6 27.3 0.27 12.0 0.7 14.6 16 0 0 16 16 15 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK36095.1 - 2e-08 34.3 16.9 0.13 12.5 1.2 8.7 10 0 0 10 10 9 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KIK36095.1 - 9.1e-08 32.1 38.9 0.013 15.6 0.2 10.6 12 1 0 12 12 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK36095.1 - 4.4e-05 23.2 28.5 0.23 11.6 0.2 11.2 13 0 0 13 13 12 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIK36095.1 - 5e-05 23.3 6.2 0.19 11.9 0.0 5.5 7 0 0 7 7 5 2 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.8 KIK36095.1 - 6.7e-05 22.0 9.6 0.047 12.6 0.0 4.9 6 0 0 6 6 6 2 NMDA receptor-regulated protein 1 Coatomer_E PF04733.14 KIK36095.1 - 0.00096 18.6 1.1 0.37 10.2 0.1 3.8 4 0 0 4 4 4 1 Coatomer epsilon subunit PknG_TPR PF16918.5 KIK36095.1 - 0.0022 16.8 0.4 0.0022 16.8 0.4 3.9 6 0 0 6 6 6 1 Protein kinase G tetratricopeptide repeat TPR_15 PF13429.6 KIK36095.1 - 0.0028 16.9 22.5 0.43 9.7 0.1 7.1 5 4 2 7 7 7 2 Tetratricopeptide repeat DUF4919 PF16266.5 KIK36095.1 - 0.12 12.3 0.2 31 4.4 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4919) TPR_3 PF07720.12 KIK36095.1 - 0.15 12.1 4.9 2.9 8.0 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 KIK36095.1 - 0.19 12.1 18.8 0.61 10.4 0.7 7.4 8 1 1 9 9 7 0 Tetratricopeptide repeat BTAD PF03704.17 KIK36095.1 - 1.7 9.1 16.6 10 6.6 0.2 5.7 5 1 0 5 5 4 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 KIK36095.1 - 1.9 8.5 25.0 0.26 11.2 0.1 8.7 9 0 0 9 9 8 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KIK36095.1 - 4.5 7.7 6.1 7.5 7.0 0.4 3.5 4 0 0 4 4 3 0 Alkyl sulfatase dimerisation LSM PF01423.22 KIK36096.1 - 1e-14 54.0 0.2 1.3e-14 53.6 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIK36096.1 - 0.023 14.8 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DNA_pol3_delta2 PF13177.6 KIK36097.1 - 3.2e-12 46.5 0.2 6.5e-12 45.5 0.2 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KIK36097.1 - 2e-05 25.0 0.5 5.7e-05 23.5 0.5 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 KIK36097.1 - 9.2e-05 22.3 0.5 0.00014 21.6 0.5 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KIK36097.1 - 0.00012 22.1 0.0 0.00026 21.0 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain Rep_fac_C PF08542.11 KIK36097.1 - 0.0078 16.6 0.1 0.038 14.4 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_22 PF13401.6 KIK36097.1 - 0.015 15.6 1.5 0.29 11.4 0.7 3.0 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 KIK36097.1 - 0.03 14.0 0.1 0.071 12.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIK36097.1 - 0.041 14.3 0.6 0.28 11.5 0.2 2.5 2 2 0 2 2 2 0 AAA ATPase domain TAP_C PF03943.13 KIK36097.1 - 0.042 13.5 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 TAP C-terminal domain AAA_assoc_2 PF16193.5 KIK36097.1 - 0.045 14.1 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain AAA_33 PF13671.6 KIK36097.1 - 0.058 13.6 0.2 0.36 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KIK36097.1 - 0.065 13.0 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Phyto-Amp PF15438.6 KIK36097.1 - 0.079 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Antigenic membrane protein of phytoplasma SspB PF04386.13 KIK36097.1 - 0.099 12.5 0.1 9.4 6.1 0.0 2.4 2 0 0 2 2 2 0 Stringent starvation protein B UvrA_inter PF17760.1 KIK36097.1 - 0.1 12.7 0.4 9.4 6.4 0.6 2.6 1 1 1 2 2 2 0 UvrA interaction domain YHS PF04945.13 KIK36099.1 - 0.011 15.8 1.6 0.14 12.3 0.2 2.5 3 0 0 3 3 3 0 YHS domain Ecl1 PF12855.7 KIK36099.1 - 0.088 14.0 4.2 0.14 13.3 4.0 1.5 1 1 0 1 1 1 0 ECL1/2/3 zinc binding proteins TRAP_alpha PF03896.16 KIK36100.1 - 0.61 9.2 6.4 1 8.5 6.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit MRC1 PF09444.10 KIK36100.1 - 0.82 10.2 12.6 1.4 9.4 12.6 1.3 1 0 0 1 1 1 0 MRC1-like domain CDC45 PF02724.14 KIK36100.1 - 6.5 4.9 6.3 8.3 4.6 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Amino_oxidase PF01593.24 KIK36101.1 - 9.5e-20 71.3 0.1 6.8e-19 68.5 0.1 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Plavaka PF18759.1 KIK36103.1 - 2.6e-31 109.1 0.0 4.7e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase SRP72 PF08492.12 KIK36112.1 - 0.2 12.1 6.4 0.061 13.8 2.5 2.2 2 0 0 2 2 2 0 SRP72 RNA-binding domain DUF410 PF04190.13 KIK36113.1 - 8.7e-73 245.2 0.0 1.2e-72 244.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Arv1 PF04161.13 KIK36114.1 - 1.4e-39 136.5 0.1 1.9e-39 136.0 0.1 1.2 1 0 0 1 1 1 1 Arv1-like family zf-C2H2 PF00096.26 KIK36115.1 - 0.024 15.1 0.8 0.12 12.9 0.1 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK36115.1 - 0.59 11.1 0.5 0.59 11.1 0.5 2.7 3 1 0 3 3 3 0 C2H2-type zinc finger Steroid_dh PF02544.16 KIK36116.1 - 7.3e-35 120.2 2.4 1.1e-34 119.6 2.4 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KIK36116.1 - 0.022 14.3 0.5 0.033 13.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Asp_protease_2 PF13650.6 KIK36119.1 - 5.3e-06 27.0 0.0 1.1e-05 26.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK36119.1 - 4.6e-05 23.9 0.0 0.00011 22.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KIK36119.1 - 0.12 12.2 0.2 0.38 10.5 0.1 2.0 2 1 0 2 2 2 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 KIK36120.1 - 2.5e-08 33.9 0.1 4.9e-08 32.9 0.1 1.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase TPR_7 PF13176.6 KIK36122.1 - 0.015 15.3 0.1 0.054 13.6 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Vta1_C PF18097.1 KIK36122.1 - 0.079 12.7 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Vta1 C-terminal domain OrsD PF12013.8 KIK36123.1 - 9.3e-13 48.6 3.2 9.5e-12 45.4 0.1 3.0 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D Helicase_C PF00271.31 KIK36123.1 - 9.6e-13 48.5 0.0 1.8e-11 44.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK36123.1 - 1.3e-08 34.8 0.0 5.7e-08 32.7 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIK36123.1 - 0.00033 20.7 0.0 0.0012 18.9 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 KIK36124.1 - 0.014 15.2 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 KIK36124.1 - 0.022 12.7 0.0 0.022 12.7 0.0 1.0 1 0 0 1 1 1 0 Helicase Rhamno_transf PF11316.8 KIK36127.1 - 0.13 11.6 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative rhamnosyl transferase DUF3891 PF13030.6 KIK36129.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3891) Fungal_trans PF04082.18 KIK36130.1 - 4.2e-06 26.0 2.6 3.4e-05 23.0 2.6 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain SR-25 PF10500.9 KIK36130.1 - 8 6.0 7.7 17 4.9 7.7 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Zn_clus PF00172.18 KIK36132.1 - 7.3e-06 26.0 7.4 1.1e-05 25.5 7.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KIK36135.1 - 1.4e-49 165.0 11.2 3.2e-07 30.9 0.1 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36135.1 - 1.2e-21 76.8 0.5 0.0015 18.8 0.0 6.1 1 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK36135.1 - 1.8e-09 37.0 0.4 0.056 12.4 0.0 5.2 3 2 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK36135.1 - 1.7e-06 27.6 0.1 0.38 10.0 0.0 3.1 1 1 2 3 3 3 3 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK36135.1 - 3.8e-06 25.8 5.7 0.42 9.2 0.2 4.5 3 1 1 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK36135.1 - 4.2e-06 26.8 0.4 0.58 10.0 0.0 3.5 1 1 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK36135.1 - 2.7e-05 24.0 0.8 14 5.7 0.0 6.5 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK36135.1 - 0.0028 17.0 0.0 4.6 6.5 0.0 3.3 2 1 1 3 3 3 1 WD40-like domain IKI3 PF04762.12 KIK36135.1 - 0.017 13.2 2.0 0.064 11.2 0.4 2.4 1 1 0 2 2 2 0 IKI3 family YabA PF06156.13 KIK36137.1 - 8.6e-05 23.1 1.4 0.00023 21.7 0.4 1.9 2 0 0 2 2 2 1 Initiation control protein YabA Mod_r PF07200.13 KIK36137.1 - 0.004 17.3 0.8 0.0065 16.6 0.8 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF3450 PF11932.8 KIK36137.1 - 0.13 11.5 2.4 0.19 11.0 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TSC22 PF01166.18 KIK36137.1 - 0.7 10.2 6.3 0.31 11.4 2.3 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.15 KIK36137.1 - 2.4 8.0 6.9 2.1 8.1 4.4 2.1 2 1 1 3 3 3 0 Septum formation initiator DUF5086 PF16985.5 KIK36139.1 - 0.038 13.9 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5086) CBM_14 PF01607.24 KIK36140.1 - 0.067 13.4 0.1 0.095 12.9 0.1 1.2 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain WRKY PF03106.15 KIK36140.1 - 0.14 12.5 0.2 0.17 12.2 0.2 1.1 1 0 0 1 1 1 0 WRKY DNA -binding domain Pkinase_Tyr PF07714.17 KIK36142.1 - 3.2e-45 154.5 0.0 4.9e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK36142.1 - 5.7e-35 120.9 0.0 1.1e-34 120.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK36142.1 - 1.5e-05 24.5 0.0 2.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIK36142.1 - 0.014 15.0 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KIK36142.1 - 0.081 12.8 0.1 0.23 11.4 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1451 PF07295.11 KIK36142.1 - 0.18 11.9 0.2 0.68 10.0 0.2 1.8 2 0 0 2 2 2 0 Zinc-ribbon containing domain Peptidase_S9 PF00326.21 KIK36143.1 - 1.7e-30 106.1 0.0 2.9e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KIK36143.1 - 0.00087 18.6 0.0 0.01 15.1 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 KIK36143.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family AXE1 PF05448.12 KIK36143.1 - 0.023 13.4 0.1 0.074 11.7 0.0 1.8 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 KIK36143.1 - 0.041 13.5 0.1 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold FSH1 PF03959.13 KIK36143.1 - 0.057 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) RTA1 PF04479.13 KIK36144.1 - 7.4e-63 211.9 6.2 1.1e-62 211.4 6.2 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF3808 PF10300.9 KIK36145.1 - 1.6e-65 221.8 0.0 4.7e-65 220.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 KIK36145.1 - 0.0005 20.0 6.6 1.3 9.3 0.1 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK36145.1 - 0.0035 17.9 12.8 0.024 15.3 1.7 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK36145.1 - 0.0059 17.3 1.8 25 6.0 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIK36145.1 - 0.022 15.0 3.6 2.7 8.3 0.1 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK36145.1 - 0.11 12.8 0.2 30 5.2 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIK36145.1 - 0.26 12.0 5.5 32 5.5 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIK36145.1 - 0.41 11.4 2.6 21 6.1 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.7 KIK36147.1 - 1.3e-16 60.9 0.1 4.4e-08 33.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KIK36147.1 - 3.6e-15 55.6 0.4 2.2e-05 24.7 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KIK36147.1 - 5.2e-14 52.4 0.1 3.7e-08 33.8 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIK36147.1 - 2.5e-10 40.4 0.0 0.0011 19.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK36147.1 - 7.4e-10 38.2 0.2 0.0082 16.6 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 KIK36147.1 - 0.00018 21.3 0.0 0.0021 17.9 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain Sec23_trunk PF04811.15 KIK36147.1 - 0.0049 16.5 0.0 0.36 10.4 0.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain KxDL PF10241.9 KIK36147.1 - 0.015 15.5 0.5 0.032 14.5 0.5 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein CREPT PF16566.5 KIK36147.1 - 0.037 14.2 0.1 0.13 12.4 0.1 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Laminin_I PF06008.14 KIK36147.1 - 0.049 13.3 2.2 0.056 13.1 0.9 1.7 2 0 0 2 2 2 0 Laminin Domain I DSPn PF14671.6 KIK36149.1 - 1.4e-39 135.8 0.0 7.7e-38 130.1 0.0 2.4 2 1 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KIK36149.1 - 8.8e-16 57.9 0.0 1.6e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIK36149.1 - 0.003 17.2 0.0 0.0048 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KIK36149.1 - 0.011 15.8 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate URO-D PF01208.17 KIK36150.1 - 6.1e-127 423.5 0.0 6.9e-127 423.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) COMPASS-Shg1 PF05205.12 KIK36151.1 - 1.6e-15 57.7 0.0 1.9e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 EnY2 PF10163.9 KIK36151.1 - 0.2 12.1 0.0 0.5 10.8 0.0 1.7 1 1 0 1 1 1 0 Transcription factor e(y)2 p450 PF00067.22 KIK36152.1 - 9e-55 186.2 0.0 1e-54 186.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK36153.1 - 1.3e-59 202.2 0.0 1.4e-59 202.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DEC1 PF15859.5 KIK36153.1 - 0.15 12.1 0.0 2 8.5 0.0 2.5 2 0 0 2 2 2 0 Deleted in esophageal cancer 1 family Ead_Ea22 PF13935.6 KIK36155.1 - 0.0091 16.7 1.2 0.013 16.1 1.2 1.2 1 0 0 1 1 1 1 Ead/Ea22-like protein ABC_tran_CTD PF16326.5 KIK36155.1 - 5.3 7.4 9.0 32 4.9 0.8 3.4 2 1 1 3 3 3 0 ABC transporter C-terminal domain RVT_1 PF00078.27 KIK36156.1 - 8.9e-08 31.9 0.0 2e-07 30.7 0.0 1.7 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 KIK36157.1 - 3.8e-08 33.9 1.7 1.3e-07 32.2 1.7 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase HTH_23 PF13384.6 KIK36157.1 - 0.048 13.5 1.0 0.46 10.4 0.7 2.2 2 0 0 2 2 2 0 Homeodomain-like domain Actin PF00022.19 KIK36158.1 - 9.2e-146 485.6 0.0 5.9e-145 482.9 0.0 1.8 1 1 0 1 1 1 1 Actin DFP PF04127.15 KIK36160.1 - 1e-20 74.3 0.0 1.4e-12 47.8 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein PAS_9 PF13426.7 KIK36160.1 - 0.16 12.3 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 PAS domain Cu-oxidase PF00394.22 KIK36161.1 - 1.4e-42 145.5 0.7 7.7e-40 136.6 0.0 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK36161.1 - 1.1e-37 128.6 0.8 3.6e-36 123.8 0.1 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK36161.1 - 6.2e-37 126.4 7.6 4.1e-36 123.7 0.2 3.4 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KIK36162.1 - 2.3e-50 170.8 0.9 1.5e-46 158.4 0.1 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK36162.1 - 1.8e-38 131.4 3.6 4e-37 127.0 0.2 3.5 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK36162.1 - 7.8e-35 119.5 0.7 5e-34 116.9 0.1 2.6 3 0 0 3 3 3 1 Multicopper oxidase DUF4229 PF14012.6 KIK36163.1 - 0.023 14.8 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF2275 PF10039.9 KIK36163.1 - 0.043 13.9 0.0 0.05 13.7 0.0 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) Gemini_mov PF01708.16 KIK36163.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Geminivirus putative movement protein Flavin_Reduct PF01613.18 KIK36165.1 - 0.086 12.9 0.1 0.091 12.8 0.1 1.1 1 0 0 1 1 1 0 Flavin reductase like domain VWA_2 PF13519.6 KIK36166.1 - 2.4e-23 82.8 1.7 7.5e-23 81.2 0.1 2.4 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 KIK36166.1 - 2.5e-09 37.6 0.4 4.7e-09 36.7 0.4 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.20 KIK36166.1 - 3.3e-08 32.9 22.5 0.00092 19.0 2.7 3.7 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.14 KIK36166.1 - 1.3e-07 31.7 0.1 1.9e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like Pectate_lyase_3 PF12708.7 KIK36166.1 - 1.2e-05 25.3 0.9 0.00078 19.3 0.0 2.6 3 0 0 3 3 3 1 Pectate lyase superfamily protein Na_trans_assoc PF06512.13 KIK36166.1 - 0.035 14.4 0.8 0.053 13.8 0.8 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated NDUF_B7 PF05676.13 KIK36167.1 - 8.9e-33 111.8 4.2 1.1e-32 111.5 4.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Ald_Xan_dh_C2 PF02738.18 KIK36167.1 - 0.062 11.7 0.3 0.074 11.5 0.3 1.0 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase SCO1-SenC PF02630.14 KIK36168.1 - 8.9e-46 155.1 0.0 1.2e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KIK36168.1 - 0.00025 20.9 0.0 0.0014 18.5 0.0 2.0 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KIK36168.1 - 0.0028 17.9 0.0 0.0062 16.8 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Ifi-6-16 PF06140.13 KIK36169.1 - 1.1e-06 28.5 0.4 2.5e-06 27.3 0.4 1.6 1 0 0 1 1 1 1 Interferon-induced 6-16 family Amidohydro_1 PF01979.20 KIK36173.1 - 2.8e-19 69.6 0.2 1.8e-16 60.4 0.0 3.0 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KIK36173.1 - 1.3e-09 38.1 2.0 1.1e-05 25.1 0.1 2.4 2 1 0 2 2 2 2 Amidohydrolase family Asp PF00026.23 KIK36175.1 - 8.3e-69 232.4 2.9 1.1e-68 232.0 2.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK36175.1 - 1.3e-12 48.3 11.6 1.2e-08 35.4 0.6 3.3 1 1 2 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK36175.1 - 0.019 15.6 0.6 0.94 10.2 0.2 3.0 2 1 0 2 2 2 0 Aspartyl protease TPR_10 PF13374.6 KIK36176.1 - 2e-73 240.5 62.4 1.9e-05 24.4 0.1 23.9 25 0 0 25 25 25 17 Tetratricopeptide repeat CHAT PF12770.7 KIK36176.1 - 1.3e-44 152.8 0.0 3.8e-44 151.2 0.0 1.8 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 KIK36176.1 - 3.4e-26 91.3 66.6 0.084 13.2 0.6 21.7 8 3 14 23 23 23 9 Tetratricopeptide repeat TPR_7 PF13176.6 KIK36176.1 - 3.2e-21 73.8 20.8 1.5 9.0 0.0 18.9 19 2 1 20 20 20 4 Tetratricopeptide repeat DUF4471 PF14740.6 KIK36176.1 - 4.8e-12 45.7 0.0 7.3 5.7 0.0 11.3 14 0 0 14 14 14 1 Domain of unknown function (DUF4471) TPR_1 PF00515.28 KIK36176.1 - 3.6e-08 32.9 43.2 16 5.5 0.0 18.5 21 1 0 21 21 20 0 Tetratricopeptide repeat DUF1968 PF09291.10 KIK36176.1 - 3.2e-06 27.1 0.0 5.3 7.2 0.0 6.7 9 0 0 9 9 9 1 Domain of unknown function (DUF1968) TPR_11 PF13414.6 KIK36176.1 - 2.5e-05 23.8 23.7 23 4.8 0.0 14.0 18 0 0 18 18 18 0 TPR repeat TPR_14 PF13428.6 KIK36176.1 - 9.3e-05 22.9 64.1 16 6.6 0.0 20.5 24 2 2 26 26 23 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK36176.1 - 0.0016 18.5 0.2 67 4.1 0.0 7.9 8 0 0 8 8 8 0 Tetratricopeptide repeat HTH_27 PF13463.6 KIK36176.1 - 0.044 14.3 0.3 1.7e+02 2.8 0.0 7.2 11 0 0 11 11 10 0 Winged helix DNA-binding domain TPR_16 PF13432.6 KIK36176.1 - 0.11 13.2 53.1 3.9 8.2 0.1 14.6 12 4 5 17 17 17 0 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 KIK36176.1 - 3.9 7.6 18.5 2.2e+02 2.0 0.0 10.7 16 0 0 16 16 13 0 Exonuclease VII small subunit SIR2 PF02146.17 KIK36177.1 - 0.16 11.9 0.0 0.16 11.9 0.0 1.0 1 0 0 1 1 1 0 Sir2 family WD40 PF00400.32 KIK36178.1 - 1.7e-62 205.9 14.6 4.9e-10 39.9 0.6 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36178.1 - 5.8e-20 71.4 0.1 0.039 14.3 0.0 6.1 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK36178.1 - 6.4e-18 64.8 2.4 0.02 13.8 0.0 6.1 4 1 2 6 6 6 5 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK36178.1 - 3.3e-09 36.4 11.7 1.1 9.3 0.1 6.4 6 0 0 6 6 6 4 WD40-like Beta Propeller Repeat NACHT PF05729.12 KIK36178.1 - 3.2e-05 23.9 0.0 6.9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK36178.1 - 4e-05 24.1 0.1 0.00016 22.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Peptidase_S9_N PF02897.15 KIK36178.1 - 8.6e-05 21.5 0.0 0.69 8.6 0.0 4.0 1 1 2 4 4 4 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Nup160 PF11715.8 KIK36178.1 - 9.8e-05 21.2 0.1 3.5 6.2 0.0 4.7 2 1 3 5 5 5 2 Nucleoporin Nup120/160 NB-ARC PF00931.22 KIK36178.1 - 0.038 13.2 0.0 0.069 12.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Nbas_N PF15492.6 KIK36178.1 - 0.041 13.2 6.4 17 4.7 0.1 5.1 4 1 1 6 6 6 0 Neuroblastoma-amplified sequence, N terminal Parvo_NS1 PF01057.17 KIK36178.1 - 0.064 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Bile_Hydr_Trans PF04775.14 KIK36178.1 - 0.11 12.6 0.0 5.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region RNA_helicase PF00910.22 KIK36178.1 - 0.19 12.1 0.0 0.53 10.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF5570 PF17731.1 KIK36178.1 - 3.5 7.7 11.8 8 6.6 0.2 5.3 1 1 5 6 6 6 0 Family of unknown function (DUF5570) KDZ PF18758.1 KIK36179.1 - 5.6e-36 124.2 1.3 5.6e-36 124.2 1.3 1.6 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase GST_N_3 PF13417.6 KIK36180.1 - 8.3e-09 35.7 0.1 2.9e-08 34.0 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK36180.1 - 3.5e-06 27.2 0.0 8e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIK36180.1 - 0.00051 20.2 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK36180.1 - 0.0065 16.5 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIK36180.1 - 0.011 15.9 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Plavaka PF18759.1 KIK36181.1 - 4.6e-35 121.4 0.0 9.9e-35 120.3 0.0 1.5 1 0 0 1 1 1 1 Plavaka transposase Metallothio_Cad PF07846.11 KIK36181.1 - 0.064 13.4 1.7 0.13 12.4 1.7 1.5 1 0 0 1 1 1 0 Metallothionein family FAD_binding_2 PF00890.24 KIK36184.1 - 4.5e-96 322.5 0.1 8.6e-96 321.5 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KIK36184.1 - 4.7e-06 26.6 0.0 8.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Cep57_CLD_2 PF14197.6 KIK36186.1 - 0.14 12.3 0.6 0.25 11.4 0.6 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 F-box-like PF12937.7 KIK36187.1 - 2.1e-07 30.7 0.6 2.1e-07 30.7 0.6 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK36187.1 - 5.1e-06 26.2 0.2 1.3e-05 24.9 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KIK36187.1 - 0.072 13.0 0.1 0.21 11.5 0.1 1.8 1 0 0 1 1 1 0 F-box AhpC-TSA PF00578.21 KIK36188.1 - 3.8e-39 133.4 0.0 5.4e-39 132.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIK36188.1 - 5.8e-14 52.0 0.0 8.2e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KIK36188.1 - 1.4e-10 40.8 0.0 2.4e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Peptidase_M48 PF01435.18 KIK36189.1 - 1.1e-30 106.9 0.1 2.2e-30 105.9 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M48 DUF4256 PF14066.6 KIK36189.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) DUF3337 PF11816.8 KIK36192.1 - 4.1e-51 173.3 0.0 6.6e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KIK36192.1 - 1.2e-18 67.1 14.3 0.00016 22.4 0.1 7.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KIK36192.1 - 0.0045 16.0 0.0 0.011 14.7 0.0 1.6 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK36192.1 - 0.018 13.7 0.1 2 6.9 0.1 2.7 1 1 1 2 2 2 0 Nucleoporin Nup120/160 RAWUL PF16207.5 KIK36192.1 - 0.035 14.8 0.0 0.065 13.9 0.0 1.5 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like ANAPC4_WD40 PF12894.7 KIK36192.1 - 0.058 13.7 0.0 0.63 10.4 0.0 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KIK36192.1 - 0.06 12.3 0.6 4.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain polyprenyl_synt PF00348.17 KIK36193.1 - 2e-85 285.9 0.0 2.5e-85 285.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase zf-C2H2 PF00096.26 KIK36194.1 - 3.1e-08 33.6 16.6 6.8e-06 26.3 0.4 4.3 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK36194.1 - 5.1e-08 33.0 6.6 1.9e-06 28.1 0.2 3.6 3 0 0 3 3 3 1 Zinc-finger double domain FOXP-CC PF16159.5 KIK36194.1 - 1.2e-05 25.8 11.9 0.066 13.8 3.1 3.8 3 1 1 4 4 4 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KIK36194.1 - 0.0013 18.6 3.6 0.049 13.6 0.1 3.6 4 0 0 4 4 4 1 C2H2-type zinc finger zf-met PF12874.7 KIK36194.1 - 0.0038 17.6 0.4 4 8.0 0.0 3.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KIK36194.1 - 0.0058 16.9 0.4 0.0058 16.9 0.4 2.2 3 0 0 3 3 3 1 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 KIK36194.1 - 0.017 15.9 0.4 0.017 15.9 0.4 3.6 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KIK36194.1 - 0.15 11.8 0.8 11 5.8 0.0 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type Zap1_zf2 PF18217.1 KIK36194.1 - 2.8 8.0 10.4 0.46 10.5 2.1 3.0 2 1 0 2 2 2 0 Zap1 zinc finger 2 Transp_cyt_pur PF02133.15 KIK36197.1 - 4.1e-66 223.6 29.1 4.8e-65 220.0 29.1 2.3 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NDUF_B12 PF08122.12 KIK36197.1 - 2.1 8.4 10.4 3.1 7.9 0.1 3.6 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Piwi PF02171.17 KIK36198.1 - 4.7e-79 265.8 0.0 6.6e-79 265.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KIK36198.1 - 1.4e-22 80.8 0.0 3.2e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KIK36198.1 - 2.2e-15 56.1 0.1 5.7e-15 54.7 0.1 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KIK36198.1 - 7.3e-12 45.4 0.1 1.7e-11 44.3 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 KIK36198.1 - 7.7e-11 42.0 0.2 1.5e-10 41.1 0.2 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KIK36198.1 - 0.013 15.8 0.0 0.035 14.3 0.0 1.8 1 0 0 1 1 1 0 Mid domain of argonaute F-box PF00646.33 KIK36199.1 - 3.5e-08 33.1 3.4 1.1e-07 31.5 3.4 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK36199.1 - 2.6e-07 30.4 2.4 8.9e-07 28.7 2.4 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIK36199.1 - 0.034 14.6 0.1 0.034 14.6 0.1 4.6 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) GGA_N-GAT PF18308.1 KIK36200.1 - 0.025 14.2 0.0 0.9 9.2 0.0 2.3 2 0 0 2 2 2 0 GGA N-GAT domain CBM_5_12 PF02839.14 KIK36201.1 - 0.41 11.3 15.2 0.15 12.7 7.5 3.9 3 0 0 3 3 3 0 Carbohydrate binding domain FSA_C PF10479.9 KIK36201.1 - 8.8 4.3 13.7 12 3.8 13.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DRY_EERY PF09750.9 KIK36202.1 - 0.00017 21.9 1.5 0.00054 20.3 1.5 1.8 1 1 0 1 1 1 1 Alternative splicing regulator Amino_oxidase PF01593.24 KIK36203.1 - 5.1e-51 174.4 0.0 1.4e-50 173.0 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK36203.1 - 1e-10 41.7 0.0 2.6e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK36203.1 - 0.00014 21.6 0.0 0.16 11.5 0.0 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIK36203.1 - 0.081 12.9 0.0 0.98 9.4 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KIK36203.1 - 0.097 11.9 0.0 0.24 10.6 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK36203.1 - 0.16 11.1 0.1 0.26 10.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Peptidase_M48_N PF16491.5 KIK36204.1 - 1.1e-62 211.2 5.5 1.1e-62 211.2 5.5 1.9 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KIK36204.1 - 1.3e-37 129.5 0.0 3.1e-37 128.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M48 SprT-like PF10263.9 KIK36204.1 - 0.11 12.4 0.2 0.2 11.5 0.2 1.3 1 0 0 1 1 1 0 SprT-like family Peptidase_M56 PF05569.11 KIK36204.1 - 0.4 9.8 3.2 0.17 11.0 0.7 1.6 2 0 0 2 2 2 0 BlaR1 peptidase M56 DUF2569 PF10754.9 KIK36204.1 - 1.1 9.7 9.0 0.59 10.6 2.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) DUF1772 PF08592.11 KIK36204.1 - 2.3 8.5 6.4 0.55 10.5 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) ATG22 PF11700.8 KIK36205.1 - 1.2e-148 495.8 14.6 1.3e-148 495.6 14.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KIK36205.1 - 7.8e-12 44.8 50.3 9.3e-08 31.4 24.0 3.2 2 2 1 3 3 3 3 Major Facilitator Superfamily DUF1634 PF07843.11 KIK36205.1 - 0.35 11.0 5.4 0.87 9.7 3.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) TPP_enzyme_N PF02776.18 KIK36206.1 - 8.8e-34 116.6 0.1 1.2e-33 116.1 0.1 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KIK36206.1 - 1.3e-15 57.4 0.0 2.6e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KIK36206.1 - 9.4e-13 48.2 0.2 4e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF4763 PF15960.5 KIK36206.1 - 0.28 10.5 3.0 0.2 10.9 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) RicinB_lectin_2 PF14200.6 KIK36208.1 - 0.0012 19.5 0.0 29 5.5 0.1 3.1 1 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like PA14 PF07691.12 KIK36208.1 - 0.15 11.9 0.0 5.7 6.7 0.0 2.2 2 0 0 2 2 2 0 PA14 domain DASH_Dad1 PF08649.10 KIK36210.1 - 1.2e-22 79.8 0.6 1.8e-22 79.3 0.6 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 KIK36210.1 - 0.012 15.5 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad4 Blo-t-5 PF11642.8 KIK36210.1 - 0.072 13.1 0.0 0.09 12.8 0.0 1.2 1 0 0 1 1 1 0 Mite allergen Blo t 5 Pkinase PF00069.25 KIK36211.1 - 1.9e-63 214.3 0.0 5.6e-63 212.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK36211.1 - 1.7e-35 122.6 0.0 2.6e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 KIK36211.1 - 2.4e-22 78.8 12.9 8.5e-14 51.4 3.3 2.4 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 KIK36211.1 - 6.5e-20 70.8 27.4 1.6e-11 43.9 10.0 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KIK36211.1 - 1.5e-11 44.8 2.2 3.5e-10 40.4 0.7 2.9 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 KIK36211.1 - 2.9e-07 30.7 0.0 5.6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain FTA2 PF13095.6 KIK36211.1 - 0.057 13.0 0.1 1.5 8.4 0.0 2.4 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 C1_2 PF03107.16 KIK36211.1 - 0.33 11.3 22.2 2.1 8.7 7.7 2.5 2 0 0 2 2 2 0 C1 domain Uds1 PF15456.6 KIK36211.1 - 1.5 9.0 11.1 0.36 11.0 1.4 2.9 3 0 0 3 3 3 0 Up-regulated During Septation Endosulfine PF04667.17 KIK36214.1 - 2.7e-27 94.7 0.3 4.2e-27 94.1 0.0 1.4 2 0 0 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region DNA_pol_E_B PF04042.16 KIK36215.1 - 3.4e-31 108.3 0.4 4.7e-31 107.8 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 KIK36215.1 - 5.7e-20 72.3 0.1 2.1e-10 41.0 0.1 2.2 1 1 1 2 2 2 2 DNA polymerase alpha subunit B N-terminal Metallophos_3 PF14582.6 KIK36215.1 - 0.018 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily LEA_4 PF02987.16 KIK36216.1 - 0.44 10.7 2.3 0.72 10.0 2.3 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant protein JmjC PF02373.22 KIK36218.1 - 2.2e-36 124.7 0.0 4.2e-36 123.8 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 KIK36218.1 - 1.1e-14 54.0 0.1 2.4e-14 53.0 0.1 1.6 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.6 KIK36218.1 - 9.5e-14 51.4 1.6 9.5e-14 51.4 1.6 2.0 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KIK36218.1 - 1.3e-12 47.8 1.2 1.3e-12 47.8 1.2 2.4 3 0 0 3 3 3 1 PHD-zinc-finger like domain NOT2_3_5 PF04153.18 KIK36218.1 - 0.0078 16.3 0.2 0.018 15.1 0.2 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family FANCL_C PF11793.8 KIK36218.1 - 0.094 12.9 2.0 0.22 11.7 2.0 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 KIK36218.1 - 2 8.4 11.7 0.019 14.8 3.2 2.1 2 0 0 2 2 2 0 PHD-finger OTCace PF00185.24 KIK36219.1 - 1.4e-43 148.7 0.0 1.8e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KIK36219.1 - 2.7e-42 144.3 0.0 4.4e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OCD_Mu_crystall PF02423.15 KIK36219.1 - 0.062 12.2 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family ABC1 PF03109.16 KIK36220.1 - 1.4e-28 99.5 0.2 2.8e-28 98.5 0.2 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KIK36220.1 - 0.073 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family TMEM135_C_rich PF15982.5 KIK36222.1 - 0.032 14.8 0.1 0.035 14.7 0.1 1.0 1 0 0 1 1 1 0 N-terminal cysteine-rich region of Transmembrane protein 135 Aminotran_5 PF00266.19 KIK36223.1 - 1.1e-31 110.2 0.0 1.3e-30 106.6 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KIK36223.1 - 0.036 13.3 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase PseudoU_synth_2 PF00849.22 KIK36226.1 - 1.4e-24 87.0 0.0 2.1e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ub-RnfH PF03658.14 KIK36226.1 - 0.2 12.0 0.2 0.76 10.2 0.0 1.9 2 0 0 2 2 2 0 RnfH family Ubiquitin Sugar_tr PF00083.24 KIK36227.1 - 1.8e-111 373.2 17.6 2.2e-111 372.9 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK36227.1 - 9e-25 87.3 27.8 9e-25 87.3 27.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK36227.1 - 0.00094 17.7 0.7 0.0016 16.9 0.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_2_3 PF16080.5 KIK36227.1 - 0.083 12.7 6.0 0.82 9.5 0.4 3.7 3 0 0 3 3 3 0 Bacteriophage holin family HP1 HSF_DNA-bind PF00447.17 KIK36231.1 - 6.9e-18 65.0 0.8 1.5e-17 64.0 0.8 1.5 1 1 0 1 1 1 1 HSF-type DNA-binding Plavaka PF18759.1 KIK36235.1 - 5.8e-41 140.8 0.0 7.7e-41 140.4 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase ATE_N PF04376.13 KIK36236.1 - 0.066 13.6 0.0 0.091 13.2 0.0 1.3 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, N terminus DUF3053 PF11254.8 KIK36236.1 - 0.11 12.0 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) Dimer_Tnp_hAT PF05699.14 KIK36238.1 - 4.7e-11 42.3 0.0 5.6e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Sigma54_CBD PF04963.13 KIK36241.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.0 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain RT_RNaseH_2 PF17919.1 KIK36246.1 - 1.8e-09 37.6 0.0 2e-09 37.4 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KIK36246.1 - 0.056 13.7 0.0 0.084 13.2 0.0 1.3 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KIK36247.1 - 5e-06 26.5 0.0 1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KIK36247.1 - 1.2e-05 25.4 0.1 3.8e-05 23.9 0.0 1.8 2 1 1 3 3 3 1 Integrase core domain TRAPP PF04051.16 KIK36248.1 - 1.8e-35 121.8 0.0 2.2e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Haemagg_act PF05860.13 KIK36248.1 - 0.14 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 haemagglutination activity domain ABC_tran PF00005.27 KIK36249.1 - 2.2e-46 157.8 0.0 6.1e-22 78.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KIK36249.1 - 8.9e-23 80.1 4.5 8.9e-23 80.1 4.5 2.5 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 KIK36249.1 - 6.4e-16 59.0 11.3 0.00046 20.1 0.1 5.0 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIK36249.1 - 2.3e-08 33.8 0.3 0.021 14.3 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KIK36249.1 - 2.5e-07 30.7 0.1 0.0085 16.2 0.1 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KIK36249.1 - 3.1e-07 30.0 0.2 0.012 15.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 KIK36249.1 - 1.2e-06 29.1 0.3 0.065 13.8 0.0 4.3 4 0 0 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 KIK36249.1 - 3.4e-06 27.1 0.1 0.08 12.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 KIK36249.1 - 5.9e-06 26.3 0.2 0.17 11.8 0.0 2.9 3 0 0 3 3 3 2 NACHT domain AAA_22 PF13401.6 KIK36249.1 - 6.3e-06 26.5 0.2 0.25 11.6 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KIK36249.1 - 6.4e-06 26.7 0.3 0.5 10.7 0.1 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_28 PF13521.6 KIK36249.1 - 1e-05 25.8 0.1 0.038 14.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 KIK36249.1 - 1.9e-05 23.8 0.1 0.02 13.9 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 KIK36249.1 - 3.7e-05 24.3 9.0 0.014 15.9 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_24 PF13479.6 KIK36249.1 - 0.00034 20.4 0.0 0.55 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KIK36249.1 - 0.00081 19.6 0.8 1.5 9.0 0.0 3.7 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 KIK36249.1 - 0.0015 18.9 0.0 1.8 9.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_15 PF13175.6 KIK36249.1 - 0.0052 16.5 9.6 0.29 10.8 0.1 3.9 5 0 0 5 5 5 2 AAA ATPase domain Roc PF08477.13 KIK36249.1 - 0.008 16.4 0.0 3.7 7.8 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 KIK36249.1 - 0.0091 16.4 0.0 7.3 7.0 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KIK36249.1 - 0.0094 16.0 0.0 8.6 6.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KIK36249.1 - 0.013 15.5 0.0 5.1 7.0 0.0 2.5 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 KIK36249.1 - 0.014 14.6 0.0 3.5 6.7 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 KIK36249.1 - 0.017 14.9 0.3 3.4 7.3 0.1 2.9 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 KIK36249.1 - 0.02 14.1 0.0 1.1 8.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KIK36249.1 - 0.027 14.0 0.0 6.1 6.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 KIK36249.1 - 0.033 14.3 0.1 0.033 14.3 0.1 3.6 4 1 1 5 5 4 0 Helicase HerA, central domain AAA_5 PF07728.14 KIK36249.1 - 0.033 14.2 0.1 7 6.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KIK36249.1 - 0.035 13.7 0.6 9.2 5.8 0.0 3.5 4 0 0 4 4 4 0 AAA domain Ploopntkinase3 PF18751.1 KIK36249.1 - 0.036 14.0 0.0 2.2 8.1 0.0 2.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Dynamin_N PF00350.23 KIK36249.1 - 0.037 14.1 0.0 6.2 6.9 0.1 2.9 2 0 0 2 2 2 0 Dynamin family cobW PF02492.19 KIK36249.1 - 0.051 13.2 0.1 13 5.3 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 KIK36249.1 - 0.26 11.6 2.9 3.1 8.1 0.2 3.7 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Agglutinin_C PF18021.1 KIK36249.1 - 0.82 10.2 3.6 3.7 8.1 0.6 2.8 3 0 0 3 3 3 0 Agglutinin C-terminal DNA_topoisoIV PF00521.20 KIK36250.1 - 9.6e-130 433.3 0.1 1.6e-129 432.5 0.1 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KIK36250.1 - 2.7e-52 176.4 0.8 2.7e-52 176.4 0.8 2.7 3 0 0 3 3 3 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KIK36250.1 - 3.6e-29 101.5 2.7 8.1e-29 100.3 2.7 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KIK36250.1 - 1.1e-11 45.2 0.1 2.9e-11 43.8 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KIK36250.1 - 8.8e-09 35.5 0.0 1.9e-07 31.2 0.0 2.8 2 0 0 2 2 2 1 Toprim domain APAF1_C PF17908.1 KIK36250.1 - 0.052 13.5 0.5 0.16 11.9 0.1 2.1 2 0 0 2 2 2 0 APAF-1 helical domain SMI1_KNR4 PF09346.10 KIK36250.1 - 0.13 12.7 0.7 0.43 11.0 0.1 2.2 2 1 0 2 2 2 0 SMI1 / KNR4 family (SUKH-1) PAM2 PF07145.15 KIK36251.1 - 0.0093 15.6 2.3 0.69 9.7 0.2 2.9 2 0 0 2 2 2 2 Ataxin-2 C-terminal region Oxysterol_BP PF01237.18 KIK36252.1 - 5.6e-85 285.4 0.5 1e-82 277.9 0.5 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DEAD PF00270.29 KIK36253.1 - 1.3e-47 161.8 0.0 3.1e-47 160.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK36253.1 - 5.4e-32 110.4 0.0 1e-26 93.4 0.0 3.4 2 1 1 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 KIK36253.1 - 0.00056 20.0 8.4 0.00065 19.8 0.0 3.3 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KIK36253.1 - 0.0048 16.3 0.1 0.0048 16.3 0.1 4.1 3 1 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit Semialdhyde_dh PF01118.24 KIK36253.1 - 0.045 14.2 0.0 0.18 12.3 0.0 2.0 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF1205 PF06722.12 KIK36254.1 - 0.17 12.0 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1205) DUF3413 PF11893.8 KIK36257.1 - 0.032 13.4 0.2 0.053 12.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) DUF4264 PF14084.6 KIK36258.1 - 0.2 11.3 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) Tri3 PF07428.11 KIK36259.1 - 0.012 14.6 0.0 0.83 8.5 0.0 2.1 2 0 0 2 2 2 0 15-O-acetyltransferase Tri3 TNV_CP PF03898.13 KIK36259.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Satellite tobacco necrosis virus coat protein DUF3716 PF12511.8 KIK36263.1 - 0.12 12.5 2.5 0.35 11.0 2.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) HisKA PF00512.25 KIK36265.1 - 0.031 14.3 0.7 0.15 12.1 0.0 2.7 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain p450 PF00067.22 KIK36266.1 - 6.4e-73 246.1 0.0 7.6e-73 245.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cytochrom_C PF00034.21 KIK36269.1 - 1.1e-09 39.3 0.0 1.4e-09 39.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KIK36269.1 - 6.1e-08 32.9 0.4 2.9e-07 30.7 0.4 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KIK36269.1 - 0.0012 18.6 0.8 0.024 14.3 0.8 2.6 1 1 0 1 1 1 1 Cytochrome c-550 domain DUF2070 PF09843.9 KIK36270.1 - 0.015 13.6 7.1 0.02 13.2 7.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3671 PF12420.8 KIK36270.1 - 0.44 10.6 0.0 0.44 10.6 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function PARP PF00644.20 KIK36271.1 - 7.2e-11 42.0 3.1 3.6e-09 36.5 0.7 3.2 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain zf-HIT PF04438.16 KIK36271.1 - 0.0014 18.5 2.7 0.0014 18.5 2.7 4.5 4 0 0 4 4 4 1 HIT zinc finger DUF2116 PF09889.9 KIK36271.1 - 0.017 15.1 0.7 0.017 15.1 0.7 2.9 4 0 0 4 4 4 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) RPAP2_Rtr1 PF04181.13 KIK36271.1 - 0.22 11.9 16.5 1.2 9.5 3.1 3.6 2 1 1 3 3 3 0 Rtr1/RPAP2 family PARP PF00644.20 KIK36272.1 - 1.8e-06 27.7 0.0 0.0002 21.0 0.0 2.7 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain DUF1768 PF08719.11 KIK36273.1 - 3e-31 108.8 0.0 4.3e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Rhodanese_C PF12368.8 KIK36273.1 - 0.16 12.4 7.4 0.28 11.6 7.4 1.4 1 0 0 1 1 1 0 Rhodanase C-terminal Fer4_11 PF13247.6 KIK36273.1 - 0.16 12.1 8.9 1.8 8.7 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain YyzF PF14116.6 KIK36273.1 - 0.81 9.8 5.4 2.2 8.4 0.2 2.4 2 0 0 2 2 2 0 YyzF-like protein GBP_C PF02841.14 KIK36274.1 - 0.09 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain FOXP-CC PF16159.5 KIK36274.1 - 0.15 12.8 0.3 0.63 10.7 0.0 2.2 2 0 0 2 2 2 0 FOXP coiled-coil domain Coq4 PF05019.13 KIK36275.1 - 5.2e-92 307.2 0.0 6e-92 306.9 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Inhibitor_I9 PF05922.16 KIK36280.1 - 0.12 13.0 0.1 0.18 12.5 0.1 1.2 1 0 0 1 1 1 0 Peptidase inhibitor I9 APP_E2 PF12925.7 KIK36283.1 - 0.0061 16.3 0.1 0.0064 16.2 0.1 1.1 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein MULE PF10551.9 KIK36286.1 - 1.1e-05 25.7 0.0 3.7e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 MULE transposase domain Kazal_1 PF00050.21 KIK36286.1 - 0.091 12.8 1.9 0.16 12.0 0.3 2.1 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain YlqD PF11068.8 KIK36289.1 - 0.028 14.8 0.2 0.041 14.3 0.2 1.2 1 0 0 1 1 1 0 YlqD protein Retrotran_gag_2 PF14223.6 KIK36290.1 - 1e-15 57.6 0.1 1.4e-15 57.2 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KIK36290.1 - 0.0026 17.8 1.1 0.0046 17.0 1.1 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF4817 PF16087.5 KIK36290.1 - 0.057 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) gag_pre-integrs PF13976.6 KIK36292.1 - 1.8e-08 34.1 0.0 2.3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 GAG-pre-integrase domain DDE_1 PF03184.19 KIK36295.1 - 7.1e-13 48.6 0.0 1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase_Tyr PF07714.17 KIK36297.1 - 4.5e-21 75.3 0.0 7.5e-21 74.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK36297.1 - 8.8e-19 67.9 0.0 1.2e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK36297.1 - 0.22 10.8 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KIK36299.1 - 2e-21 76.5 0.0 2.2e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK36299.1 - 1.6e-20 73.6 0.0 1.8e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK36299.1 - 0.0015 17.9 0.3 0.0021 17.4 0.3 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIK36299.1 - 0.0015 17.9 0.0 0.003 16.9 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KIK36299.1 - 0.0033 16.2 0.2 0.0039 16.0 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KIK36299.1 - 0.0039 16.8 0.0 0.005 16.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIK36299.1 - 0.011 15.6 0.2 0.017 15.0 0.2 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KIK36299.1 - 0.11 11.5 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 KIK36299.1 - 0.22 10.4 0.3 0.6 9.0 0.2 1.7 1 1 1 2 2 2 0 Haspin like kinase domain Atg14 PF10186.9 KIK36301.1 - 9.6e-41 139.9 0.0 4.3e-40 137.7 0.0 2.0 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4200 PF13863.6 KIK36301.1 - 0.2 12.0 2.2 3.8 8.0 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) BAR_2 PF10455.9 KIK36301.1 - 0.24 10.5 0.2 0.34 10.0 0.2 1.1 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking MFS_1 PF07690.16 KIK36302.1 - 7.5e-35 120.5 39.7 7.5e-35 120.5 39.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK36302.1 - 1.6e-05 23.9 12.6 1.6e-05 23.9 12.6 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KIK36304.1 - 6e-08 32.0 0.9 7.1e-08 31.8 0.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MMR_HSR1 PF01926.23 KIK36307.1 - 0.00022 21.3 0.0 0.00026 21.0 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK36307.1 - 0.0013 18.7 0.0 0.0014 18.5 0.0 1.1 1 0 0 1 1 1 1 RsgA GTPase Septin PF00735.18 KIK36307.1 - 0.0066 15.8 0.0 0.0069 15.7 0.0 1.0 1 0 0 1 1 1 1 Septin AAA_16 PF13191.6 KIK36307.1 - 0.0093 16.4 0.0 0.0093 16.4 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KIK36307.1 - 0.014 15.1 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KIK36307.1 - 0.016 14.8 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region Roc PF08477.13 KIK36307.1 - 0.016 15.4 0.0 0.016 15.4 0.0 1.1 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KIK36307.1 - 0.019 15.4 0.0 0.021 15.4 0.0 1.1 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KIK36307.1 - 0.06 13.6 0.0 0.061 13.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 KIK36307.1 - 0.073 12.7 0.0 0.073 12.7 0.0 1.1 1 0 0 1 1 1 0 Ras family AIG1 PF04548.16 KIK36307.1 - 0.091 12.1 0.0 0.095 12.0 0.0 1.1 1 0 0 1 1 1 0 AIG1 family DUF815 PF05673.13 KIK36307.1 - 0.11 11.6 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 KIK36307.1 - 0.16 11.2 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_8 PF12780.7 KIK36307.1 - 0.16 11.3 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 AAA_24 PF13479.6 KIK36307.1 - 0.17 11.6 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KIK36307.1 - 0.18 11.3 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1 PF01926.23 KIK36309.1 - 1.4e-07 31.6 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KIK36309.1 - 0.0001 21.8 0.1 0.0061 16.0 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KIK36309.1 - 0.00017 21.5 0.1 0.14 12.1 0.0 2.7 3 0 0 3 3 3 2 RsgA GTPase Roc PF08477.13 KIK36309.1 - 0.00035 20.8 0.1 0.00079 19.6 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 KIK36309.1 - 0.0097 16.4 0.6 0.022 15.3 0.6 1.7 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.20 KIK36309.1 - 0.022 14.0 0.1 0.027 13.6 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit ATPase_2 PF01637.18 KIK36309.1 - 0.025 14.5 0.3 0.04 13.8 0.3 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 KIK36309.1 - 0.029 14.8 0.0 0.055 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KIK36309.1 - 0.051 13.6 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KIK36309.1 - 0.061 12.7 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein Septin PF00735.18 KIK36309.1 - 0.061 12.6 0.3 0.25 10.6 0.3 1.9 1 1 0 1 1 1 0 Septin MCM PF00493.23 KIK36309.1 - 0.089 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain ABC_tran PF00005.27 KIK36309.1 - 0.1 13.1 0.0 0.14 12.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter 4HBT_3 PF13622.6 KIK36310.1 - 9.7e-22 78.4 0.4 1.2e-21 78.1 0.4 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Asp PF00026.23 KIK36311.1 - 7.1e-44 150.5 11.0 2.8e-43 148.6 11.0 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK36311.1 - 1.2e-08 35.4 8.8 0.00011 22.5 0.2 4.2 3 1 2 5 5 5 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK36311.1 - 0.0006 20.4 3.0 0.43 11.3 0.8 3.0 2 0 0 2 2 2 2 Aspartyl protease LRR_6 PF13516.6 KIK36312.1 - 6e-10 38.4 13.3 0.41 10.8 0.2 8.5 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 KIK36312.1 - 8.1e-07 29.3 16.8 0.013 15.9 3.7 5.8 5 2 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KIK36312.1 - 1.2e-05 25.2 3.8 10 7.2 0.0 6.4 7 0 0 7 7 7 1 Leucine Rich Repeat Yos9_DD PF17880.1 KIK36312.1 - 0.011 15.9 0.3 0.02 15.0 0.3 1.4 1 0 0 1 1 1 0 Yos9 dimerzation domain LRR_8 PF13855.6 KIK36312.1 - 0.026 14.3 3.9 0.026 14.3 3.9 4.6 5 0 0 5 5 5 0 Leucine rich repeat adh_short_C2 PF13561.6 KIK36312.1 - 0.46 10.0 2.7 0.72 9.4 1.9 1.8 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Sigma70_r1_1 PF03979.14 KIK36312.1 - 1 9.5 11.2 2.3 8.3 10.6 1.9 1 1 1 2 2 2 0 Sigma-70 factor, region 1.1 AAA_5 PF07728.14 KIK36313.1 - 1.7e-110 365.0 0.0 8e-20 71.2 0.0 9.8 8 1 0 9 9 9 8 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KIK36313.1 - 7.1e-53 177.3 11.5 3.2e-21 75.5 0.0 6.4 6 0 0 6 6 5 3 Midasin AAA lid domain AAA_3 PF07726.11 KIK36313.1 - 8.2e-24 83.9 0.0 2.8e-09 36.9 0.0 6.9 8 0 0 8 8 7 2 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 KIK36313.1 - 2.5e-21 75.7 0.0 1.5e-20 73.3 0.0 2.4 2 0 0 2 2 1 1 Midasin AAA lid domain AAA PF00004.29 KIK36313.1 - 1.7e-19 70.6 0.0 0.01 16.3 0.0 7.1 7 0 0 7 7 6 4 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 KIK36313.1 - 4.3e-19 68.8 0.0 6.8e-05 23.0 0.0 6.6 7 0 0 7 7 6 3 Dynein heavy chain region D6 P-loop domain AAA_7 PF12775.7 KIK36313.1 - 6.7e-19 68.1 0.0 8.6e-05 22.1 0.0 5.6 5 0 0 5 5 5 3 P-loop containing dynein motor region AAA_16 PF13191.6 KIK36313.1 - 3.7e-16 60.0 16.1 6.7e-05 23.3 0.1 9.0 7 2 0 7 7 7 4 AAA ATPase domain AAA_22 PF13401.6 KIK36313.1 - 1.5e-15 57.7 0.2 0.016 15.4 0.0 7.0 7 0 0 7 7 6 2 AAA domain Sigma54_activat PF00158.26 KIK36313.1 - 2.6e-15 56.5 0.0 0.013 15.2 0.0 6.6 7 0 0 7 7 6 4 Sigma-54 interaction domain AAA_6 PF12774.7 KIK36313.1 - 1e-12 47.7 0.0 0.018 14.0 0.0 6.3 7 0 0 7 7 7 3 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 KIK36313.1 - 1.9e-11 44.6 0.0 0.32 11.6 0.0 6.5 6 0 0 6 6 5 2 AAA domain ABC_tran PF00005.27 KIK36313.1 - 2.1e-08 34.8 0.2 5.4 7.5 0.0 5.6 5 0 0 5 5 5 0 ABC transporter AAA_14 PF13173.6 KIK36313.1 - 2.9e-08 33.8 0.0 0.06 13.4 0.0 5.5 6 0 0 6 6 5 2 AAA domain Sigma54_activ_2 PF14532.6 KIK36313.1 - 4.3e-08 33.4 0.0 0.054 13.6 0.0 4.9 4 0 0 4 4 4 2 Sigma-54 interaction domain TsaE PF02367.17 KIK36313.1 - 5e-08 33.0 0.0 9.3 6.3 0.0 5.9 6 0 0 6 6 6 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KIK36313.1 - 2.9e-07 30.1 0.3 5.2 6.4 0.0 6.8 7 0 0 7 7 7 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 KIK36313.1 - 4.7e-07 29.1 0.4 0.36 9.8 0.0 5.3 6 0 0 6 6 6 1 Type II/IV secretion system protein RNA_helicase PF00910.22 KIK36313.1 - 6.7e-07 29.7 0.2 23 5.4 0.0 6.6 6 0 0 6 6 6 0 RNA helicase AAA_8 PF12780.7 KIK36313.1 - 6.2e-06 25.7 0.0 0.03 13.6 0.0 4.4 5 0 0 5 5 4 1 P-loop containing dynein motor region D4 AAA_29 PF13555.6 KIK36313.1 - 2e-05 24.2 0.2 18 5.1 0.0 5.2 5 0 0 5 5 5 0 P-loop containing region of AAA domain AAA_19 PF13245.6 KIK36313.1 - 7.8e-05 23.0 0.3 5.4 7.3 0.0 4.9 5 0 0 5 5 4 0 AAA domain NACHT PF05729.12 KIK36313.1 - 0.00013 21.9 2.1 3.6 7.5 0.1 5.1 6 0 0 6 6 3 1 NACHT domain AAA_33 PF13671.6 KIK36313.1 - 0.00019 21.6 0.0 15 5.7 0.0 5.3 5 0 0 5 5 4 0 AAA domain DUF815 PF05673.13 KIK36313.1 - 0.00031 20.0 0.1 4.9 6.2 0.0 4.3 5 0 0 5 5 4 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 KIK36313.1 - 0.00039 20.7 2.7 2.6 8.3 0.0 5.2 5 0 0 5 5 5 1 AAA domain AAA_25 PF13481.6 KIK36313.1 - 0.00059 19.5 6.8 18 4.8 0.3 6.6 7 0 0 7 7 6 0 AAA domain Zeta_toxin PF06414.12 KIK36313.1 - 0.0011 18.3 0.0 17 4.6 0.0 5.4 6 0 0 6 6 5 0 Zeta toxin DnaB_C PF03796.15 KIK36313.1 - 0.0032 16.8 2.4 0.76 9.1 0.4 3.6 4 0 0 4 4 3 1 DnaB-like helicase C terminal domain NTPase_1 PF03266.15 KIK36313.1 - 0.0069 16.3 1.4 50 3.7 0.1 4.7 4 0 0 4 4 4 0 NTPase DEAD PF00270.29 KIK36313.1 - 0.013 15.2 0.0 9.6 5.9 0.0 3.5 3 0 0 3 3 3 0 DEAD/DEAH box helicase RuvB_N PF05496.12 KIK36313.1 - 0.014 15.1 0.3 8.4 6.1 0.0 3.8 5 0 0 5 5 4 0 Holliday junction DNA helicase RuvB P-loop domain SRP54 PF00448.22 KIK36313.1 - 0.016 14.9 0.2 23 4.5 0.0 3.5 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KIK36313.1 - 0.017 14.9 0.0 56 3.4 0.0 4.2 5 0 0 5 5 3 0 AAA domain TniB PF05621.11 KIK36313.1 - 0.059 12.8 0.0 17 4.8 0.0 3.6 4 0 0 4 4 3 0 Bacterial TniB protein Roc PF08477.13 KIK36313.1 - 0.069 13.4 1.7 26 5.0 0.0 4.3 5 0 0 5 5 4 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KIK36313.1 - 0.087 12.7 0.3 7 6.5 0.0 3.5 4 0 0 4 4 3 0 RsgA GTPase dNK PF01712.19 KIK36313.1 - 0.089 12.6 0.1 2.9 7.7 0.0 3.2 4 0 0 4 4 2 0 Deoxynucleoside kinase MMR_HSR1 PF01926.23 KIK36313.1 - 0.19 11.8 0.8 1.1e+02 3.0 0.0 4.3 5 0 0 5 5 4 0 50S ribosome-binding GTPase Rad17 PF03215.15 KIK36313.1 - 0.25 11.2 1.0 45 3.9 0.0 4.4 6 0 0 6 6 4 0 Rad17 P-loop domain PduV-EutP PF10662.9 KIK36313.1 - 0.26 11.0 1.7 3.7 7.3 0.0 3.4 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 KIK36313.1 - 0.35 11.3 8.8 38 4.7 0.0 5.0 5 0 0 5 5 3 0 AAA domain CRM1_repeat PF18777.1 KIK36315.1 - 1.6e-06 27.5 0.8 0.0002 20.8 0.0 2.3 2 0 0 2 2 2 2 Chromosome region maintenance or exportin repeat SKN1 PF03935.15 KIK36318.1 - 1.1e-129 433.2 0.2 1.4e-129 432.7 0.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Plavaka PF18759.1 KIK36322.1 - 2e-29 102.9 0.0 5.8e-29 101.3 0.0 1.7 1 1 0 1 1 1 1 Plavaka transposase FA_desaturase_2 PF03405.14 KIK36322.1 - 0.17 10.7 0.0 0.33 9.7 0.0 1.3 1 0 0 1 1 1 0 Fatty acid desaturase HGWP PF03578.15 KIK36325.1 - 0.056 13.0 0.4 0.15 11.6 0.4 1.8 1 0 0 1 1 1 0 HGWP repeat adh_short_C2 PF13561.6 KIK36326.1 - 4.2e-51 173.8 7.6 4.3e-42 144.3 4.6 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK36326.1 - 2.1e-47 161.1 3.2 2.7e-47 160.8 3.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK36326.1 - 4.8e-17 62.4 0.3 9.8e-17 61.4 0.3 1.5 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KIK36326.1 - 0.009 15.9 1.1 0.017 15.0 1.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4743 PF15916.5 KIK36326.1 - 0.042 13.8 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4743) AdoHcyase_NAD PF00670.21 KIK36326.1 - 0.051 13.6 0.7 0.088 12.9 0.7 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Methyltransf_25 PF13649.6 KIK36326.1 - 0.071 13.8 0.2 0.21 12.3 0.1 1.8 1 1 1 2 2 2 0 Methyltransferase domain Metallophos_2 PF12850.7 KIK36326.1 - 0.14 12.4 0.3 0.31 11.2 0.3 1.6 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain ERM PF00769.19 KIK36327.1 - 2.4e-05 24.3 6.7 4.8e-05 23.3 6.7 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Spc7 PF08317.11 KIK36327.1 - 0.0021 17.0 1.9 0.0022 16.9 0.8 1.5 2 0 0 2 2 2 1 Spc7 kinetochore protein TPD52 PF04201.15 KIK36327.1 - 0.0024 17.5 0.8 0.0056 16.3 0.8 1.5 1 0 0 1 1 1 1 Tumour protein D52 family THOC7 PF05615.13 KIK36327.1 - 0.0028 17.9 0.8 0.0071 16.6 0.1 2.0 2 0 0 2 2 2 1 Tho complex subunit 7 DUF641 PF04859.12 KIK36327.1 - 0.0097 16.2 1.2 0.025 14.9 1.2 1.6 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.8 KIK36327.1 - 0.0099 15.9 4.5 0.029 14.4 4.5 1.8 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding GAS PF13851.6 KIK36327.1 - 0.013 14.8 2.2 0.041 13.2 2.2 1.8 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF16 PF01519.16 KIK36327.1 - 0.02 15.4 1.4 0.043 14.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 FliJ PF02050.16 KIK36327.1 - 0.021 15.1 3.9 0.028 14.6 2.5 2.0 1 1 0 1 1 1 0 Flagellar FliJ protein SlyX PF04102.12 KIK36327.1 - 0.023 15.3 2.0 0.023 15.3 2.0 2.6 2 0 0 2 2 2 0 SlyX HMMR_N PF15905.5 KIK36327.1 - 0.081 12.4 4.2 0.14 11.6 4.2 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal PLU-1 PF08429.11 KIK36327.1 - 0.082 12.1 0.1 0.082 12.1 0.1 2.1 2 0 0 2 2 2 0 PLU-1-like protein FliM PF02154.15 KIK36327.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Flagellar motor switch protein FliM Spc24 PF08286.11 KIK36327.1 - 0.19 12.0 0.9 0.46 10.8 0.9 1.7 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DLP_helical PF18709.1 KIK36327.1 - 0.24 10.6 1.4 0.37 9.9 1.4 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain APG6_N PF17675.1 KIK36327.1 - 0.89 10.1 9.9 0.061 13.8 3.9 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region XhlA PF10779.9 KIK36327.1 - 1.2 9.4 6.1 3.2 8.0 6.1 1.7 1 0 0 1 1 1 0 Haemolysin XhlA Prefoldin_2 PF01920.20 KIK36327.1 - 1.4 8.9 8.4 0.22 11.5 3.8 1.9 2 0 0 2 2 2 0 Prefoldin subunit PRKG1_interact PF15898.5 KIK36327.1 - 3.4 8.6 8.7 14 6.6 8.7 2.1 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF21 PF01595.20 KIK36328.1 - 2.3e-26 92.6 0.1 4e-26 91.8 0.1 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CDC73_N PF16050.5 KIK36328.1 - 0.38 10.0 2.5 0.56 9.5 2.5 1.1 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal F-box-like PF12937.7 KIK36329.1 - 4e-06 26.6 2.7 2.5e-05 24.1 0.0 3.5 4 0 0 4 4 4 1 F-box-like p450 PF00067.22 KIK36330.1 - 0.0019 17.0 0.0 0.0025 16.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1959 PF09218.10 KIK36332.1 - 0.056 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1959) DDE_Tnp_1_4 PF13701.6 KIK36334.1 - 0.062 11.6 0.0 0.1 10.9 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain group 1 DUF3007 PF11460.8 KIK36334.1 - 0.94 9.8 3.0 2.2 8.6 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) bZIP_1 PF00170.21 KIK36338.1 - 6.5e-08 32.6 11.9 7.8e-08 32.3 9.1 2.0 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KIK36338.1 - 7.7e-06 25.9 13.6 0.00024 21.1 13.6 2.2 1 1 0 1 1 1 1 Basic region leucine zipper Flg_hook PF02120.16 KIK36338.1 - 0.0079 16.1 0.2 0.036 14.0 0.5 2.0 2 1 0 2 2 2 1 Flagellar hook-length control protein FliK bZIP_Maf PF03131.17 KIK36338.1 - 0.34 11.5 4.7 0.27 11.8 2.9 1.7 1 1 1 2 2 2 0 bZIP Maf transcription factor DUF1690 PF07956.11 KIK36338.1 - 0.62 10.5 3.9 1 9.8 3.9 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) ABC_tran_CTD PF16326.5 KIK36338.1 - 5.4 7.4 6.1 24 5.3 4.9 2.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain DivIC PF04977.15 KIK36338.1 - 9.9 6.0 6.2 5.1 6.9 0.4 2.2 1 1 1 2 2 2 0 Septum formation initiator DNA_pol_B_palm PF14792.6 KIK36339.1 - 1.9e-22 79.6 0.1 4.8e-22 78.3 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 KIK36339.1 - 2.3e-21 75.7 0.1 8.1e-21 74.0 0.1 2.0 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_8 PF14716.6 KIK36339.1 - 7.6e-09 35.8 0.0 8.4e-08 32.5 0.0 2.7 3 0 0 3 3 3 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 KIK36339.1 - 9.8e-09 34.9 0.0 1.2e-07 31.5 0.0 2.5 1 1 0 1 1 1 1 Fingers domain of DNA polymerase lambda BRCT_2 PF16589.5 KIK36339.1 - 0.00082 19.7 0.0 0.0028 18.0 0.0 1.9 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain HHH_5 PF14520.6 KIK36339.1 - 0.0016 19.0 0.0 0.029 15.0 0.0 2.6 3 0 0 3 3 3 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 KIK36339.1 - 0.0069 16.7 0.0 0.02 15.1 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Cdd1 PF11731.8 KIK36339.1 - 0.01 16.0 0.0 0.035 14.3 0.0 1.9 1 0 0 1 1 1 0 Pathogenicity locus Acyl-CoA_dh_N PF02771.16 KIK36341.1 - 3.7e-29 101.7 0.0 6e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KIK36341.1 - 2.4e-23 83.0 0.0 4.1e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIK36341.1 - 2e-19 69.6 0.0 4.2e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KIK36341.1 - 0.00077 19.7 0.1 0.0018 18.6 0.1 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UPF0029 PF01205.19 KIK36343.1 - 2.6e-25 88.8 0.1 5.6e-25 87.7 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RSN1_7TM PF02714.15 KIK36344.1 - 1e-73 248.0 27.8 1e-73 248.0 27.8 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KIK36344.1 - 8.5e-38 129.6 1.0 8.5e-38 129.6 1.0 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KIK36344.1 - 3.4e-37 128.4 0.0 5.1e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Nop25 PF09805.9 KIK36346.1 - 0.0052 17.3 9.5 0.0052 17.3 9.5 2.8 3 0 0 3 3 3 1 Nucleolar protein 12 (25kDa) DUF4778 PF16008.5 KIK36346.1 - 0.39 10.7 10.0 0.058 13.5 4.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) MDM10 PF12519.8 KIK36346.1 - 0.49 9.2 2.2 0.71 8.7 2.2 1.5 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 PRC2_HTH_1 PF18118.1 KIK36346.1 - 0.98 10.3 11.5 0.083 13.7 3.9 2.8 3 1 0 3 3 3 0 Polycomb repressive complex 2 tri-helical domain NPR3 PF03666.13 KIK36346.1 - 3.4 6.3 10.8 0.14 10.9 3.8 1.9 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Ferritin_2 PF13668.6 KIK36348.1 - 1.1e-41 142.3 0.0 1.5e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain Ferritin_2 PF13668.6 KIK36349.1 - 1.3e-28 99.9 0.1 1.8e-28 99.5 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain HpcH_HpaI PF03328.14 KIK36350.1 - 4.7e-31 107.7 0.0 6.5e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Phage_integrase PF00589.22 KIK36351.1 - 0.0021 17.9 0.1 0.22 11.3 0.0 2.7 3 0 0 3 3 3 2 Phage integrase family XPG_I PF00867.18 KIK36352.1 - 1.3e-09 38.3 0.0 1.7e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 XPG I-region Ammonium_transp PF00909.21 KIK36354.1 - 2.8e-120 401.7 23.5 3.2e-120 401.5 23.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family p450 PF00067.22 KIK36355.1 - 1.1e-33 116.7 0.0 2.2e-33 115.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK36356.1 - 5.1e-19 68.4 0.0 6.1e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 JUPITER PF17054.5 KIK36357.1 - 0.0024 17.4 0.4 0.0024 17.4 0.4 1.0 1 0 0 1 1 1 1 Microtubule-Associated protein Jupiter DUF4421 PF14391.6 KIK36358.1 - 0.067 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4421) PhoPQ_related PF10142.9 KIK36360.1 - 0.2 10.3 0.6 0.22 10.1 0.6 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Phage_integrase PF00589.22 KIK36362.1 - 0.0047 16.7 0.0 0.015 15.1 0.0 1.8 2 0 0 2 2 2 1 Phage integrase family F-box-like PF12937.7 KIK36364.1 - 5.9e-09 35.7 1.2 1.8e-08 34.2 1.2 1.8 1 0 0 1 1 1 1 F-box-like Aldo_ket_red PF00248.21 KIK36365.1 - 4.3e-48 164.0 0.0 5.1e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 3Beta_HSD PF01073.19 KIK36366.1 - 5.7e-30 104.3 0.0 2.9e-29 102.0 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIK36366.1 - 8.2e-10 38.3 0.0 2e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 KIK36366.1 - 8.4e-09 35.2 0.0 2.4e-08 33.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK36366.1 - 0.0029 17.5 0.0 0.0074 16.2 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KIK36366.1 - 0.035 13.2 0.3 0.43 9.6 0.3 2.0 1 1 0 1 1 1 0 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 KIK36366.1 - 0.066 13.5 0.1 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KIK36366.1 - 0.1 11.7 0.0 0.47 9.5 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 KIK36366.1 - 0.18 12.4 0.0 0.37 11.4 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ADH_N PF08240.12 KIK36367.1 - 1.1e-32 112.1 3.4 2.4e-32 111.0 3.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK36367.1 - 1.9e-16 60.3 0.0 4.7e-16 59.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIK36367.1 - 3.7e-14 52.7 0.0 5.5e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KIK36367.1 - 7.6e-08 33.5 0.0 1.3e-07 32.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KIK36367.1 - 0.00012 21.5 0.8 0.00017 20.9 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain Sacchrp_dh_NADP PF03435.18 KIK36367.1 - 0.0061 16.8 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_8 PF13450.6 KIK36367.1 - 0.18 12.1 0.5 0.39 11.0 0.5 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KIK36367.1 - 0.18 11.8 0.3 0.38 10.8 0.3 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Aldo_ket_red PF00248.21 KIK36368.1 - 6e-32 111.0 0.0 7.8e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NUC130_3NT PF08158.12 KIK36368.1 - 0.77 10.1 0.1 0.77 10.1 0.1 2.5 3 1 0 3 3 3 0 NUC130/3NT domain Cyt-b5 PF00173.28 KIK36369.1 - 1.6e-21 76.2 0.3 3.7e-21 75.1 0.3 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KIK36369.1 - 2e-12 47.6 18.1 2e-12 47.6 18.1 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily AMP-binding PF00501.28 KIK36370.1 - 1.9e-89 300.2 0.0 2.3e-89 299.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK36370.1 - 4.1e-12 46.9 0.0 1.1e-11 45.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain VIT PF08487.10 KIK36372.1 - 2.7e-19 69.4 0.1 6.6e-19 68.2 0.1 1.7 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VIT_2 PF13757.6 KIK36372.1 - 1.6e-06 27.9 0.0 3.9e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KIK36372.1 - 2.4e-05 24.3 0.0 9.2e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIK36372.1 - 0.00087 19.9 0.8 0.0044 17.6 0.8 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KIK36372.1 - 0.0076 16.5 0.1 0.036 14.3 0.1 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain Pkinase PF00069.25 KIK36374.1 - 1.7e-40 139.1 0.0 2e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK36374.1 - 1.3e-14 54.1 0.0 1.5e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIK36374.1 - 0.00022 20.7 0.1 0.00047 19.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIK36374.1 - 0.00028 20.3 0.0 0.001 18.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KIK36374.1 - 0.0031 17.5 0.1 0.0087 16.0 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK36374.1 - 0.017 14.1 0.0 0.021 13.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KIK36374.1 - 0.049 12.4 0.0 0.074 11.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Dimeth_Pyl PF09505.10 KIK36376.1 - 0.17 10.4 0.1 0.17 10.4 0.1 1.0 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) Lipase_GDSL PF00657.22 KIK36378.1 - 1.9e-05 24.8 0.0 0.00038 20.5 0.0 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KIK36378.1 - 0.00029 21.3 3.5 0.00076 19.9 3.5 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Aldedh PF00171.22 KIK36379.1 - 1e-84 284.7 0.0 1.3e-84 284.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.16 KIK36380.1 - 1.3e-26 93.4 40.2 1.3e-26 93.4 40.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily WD40 PF00400.32 KIK36383.1 - 1e-126 409.1 37.7 4.1e-10 40.1 0.1 14.9 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36383.1 - 5e-45 151.7 0.0 0.0075 16.5 0.0 13.3 2 2 10 12 12 12 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK36383.1 - 1.9e-35 122.4 13.1 0.0013 17.8 0.0 13.7 6 3 7 14 14 14 9 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK36383.1 - 3.3e-15 55.6 40.1 0.057 13.4 0.2 12.4 14 0 0 14 14 13 9 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK36383.1 - 3.1e-13 49.2 6.9 1.1 7.8 0.0 10.8 4 2 5 11 11 11 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK36383.1 - 2.6e-09 36.8 10.9 8.7 5.6 0.0 10.5 10 3 2 13 13 13 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK36383.1 - 2e-08 33.9 0.0 0.34 10.2 0.0 6.9 8 0 0 8 8 8 1 WD40-like domain AAA_16 PF13191.6 KIK36383.1 - 1.6e-07 31.9 0.2 5.4e-07 30.1 0.1 1.9 2 0 0 2 2 1 1 AAA ATPase domain NACHT PF05729.12 KIK36383.1 - 3.7e-06 26.9 0.0 7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Peptidase_S9_N PF02897.15 KIK36383.1 - 4.5e-05 22.4 0.0 8.7 5.0 0.0 5.7 4 2 1 6 6 6 0 Prolyl oligopeptidase, N-terminal beta-propeller domain CHAP PF05257.16 KIK36383.1 - 0.00016 22.2 6.9 8.7 7.0 0.1 6.4 7 2 2 9 9 6 0 CHAP domain Frtz PF11768.8 KIK36383.1 - 0.0002 19.9 0.0 20 3.3 0.0 5.6 3 2 2 6 6 6 0 WD repeat-containing and planar cell polarity effector protein Fritz AAA PF00004.29 KIK36383.1 - 0.00038 20.9 0.0 0.0011 19.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF1513 PF07433.11 KIK36383.1 - 0.00054 19.1 5.4 0.14 11.2 0.1 5.3 5 2 3 8 8 8 1 Protein of unknown function (DUF1513) PQQ PF01011.21 KIK36383.1 - 0.00061 19.6 1.4 1.2 9.1 0.0 6.2 8 0 0 8 8 8 1 PQQ enzyme repeat Cuticle_4 PF15955.5 KIK36383.1 - 0.039 14.6 0.3 1.8e+02 2.9 0.0 5.9 7 0 0 7 7 5 0 Cuticle protein Parvo_NS1 PF01057.17 KIK36383.1 - 0.071 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PQQ_2 PF13360.6 KIK36383.1 - 0.09 12.3 17.1 0.72 9.4 8.9 4.4 1 1 2 3 3 3 0 PQQ-like domain AAA_22 PF13401.6 KIK36383.1 - 0.091 13.0 0.0 0.26 11.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 KIK36383.1 - 0.16 12.3 0.0 0.52 10.7 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Spc29 PF17082.5 KIK36383.1 - 0.18 11.6 0.5 1.4 8.7 0.1 2.6 4 0 0 4 4 3 0 Spindle Pole Component 29 adh_short_C2 PF13561.6 KIK36384.1 - 6.9e-55 186.1 0.0 8.1e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK36384.1 - 4.6e-40 137.2 0.1 7.5e-40 136.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK36384.1 - 4.1e-13 49.6 0.3 5.8e-13 49.1 0.3 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK36384.1 - 0.0044 16.2 0.0 0.0055 15.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KIK36384.1 - 0.0081 15.6 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KIK36384.1 - 0.0081 15.2 0.1 0.0096 15.0 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KIK36384.1 - 0.046 14.0 0.1 0.077 13.3 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.21 KIK36384.1 - 0.049 13.1 0.1 0.081 12.4 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DEAD PF00270.29 KIK36386.1 - 7.7e-42 143.0 0.1 1.2e-41 142.4 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK36386.1 - 5.4e-27 94.3 0.6 1.4e-26 93.0 0.3 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KIK36386.1 - 0.2 11.0 0.1 0.41 9.9 0.1 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF3990 PF13151.6 KIK36387.1 - 0.054 13.2 0.2 0.06 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3990) Transp_cyt_pur PF02133.15 KIK36388.1 - 1.2e-135 452.7 44.5 1.4e-135 452.5 44.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Med12-PQL PF12144.8 KIK36389.1 - 0.0013 18.7 4.3 0.013 15.4 0.6 2.1 2 0 0 2 2 2 2 Eukaryotic Mediator 12 catenin-binding domain T2SSM PF04612.12 KIK36390.1 - 0.14 12.2 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M WD40 PF00400.32 KIK36391.1 - 5.6e-39 131.4 25.0 1.6e-07 31.9 0.0 12.9 14 0 0 14 14 13 6 WD domain, G-beta repeat Utp12 PF04003.12 KIK36391.1 - 3.8e-25 88.3 0.0 6.8e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KIK36391.1 - 4.3e-24 84.6 0.0 0.0016 18.7 0.0 9.9 3 2 7 11 11 11 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK36391.1 - 1e-09 37.8 3.4 1.1 8.2 0.0 7.3 4 3 3 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK36391.1 - 1.1e-06 28.4 4.4 12 6.0 0.0 8.6 8 0 0 8 8 8 1 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 KIK36391.1 - 0.00085 18.5 0.0 7.8 5.5 0.0 3.7 3 1 0 3 3 3 2 Protein of unknown function (DUF1513) WD40_like PF17005.5 KIK36391.1 - 0.002 17.5 0.1 0.75 9.1 0.0 3.9 4 0 0 4 4 4 1 WD40-like domain RAB3GAP2_N PF14655.6 KIK36391.1 - 0.0075 15.6 0.1 0.18 11.0 0.0 3.2 4 1 1 5 5 5 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Cytochrom_D1 PF02239.16 KIK36391.1 - 0.009 14.6 0.2 2 6.9 0.0 3.3 4 0 0 4 4 4 1 Cytochrome D1 heme domain Nup160 PF11715.8 KIK36391.1 - 0.03 13.0 0.0 21 3.6 0.0 3.5 1 1 1 3 3 3 0 Nucleoporin Nup120/160 ELYS-bb PF16687.5 KIK36391.1 - 0.095 11.3 0.0 0.31 9.6 0.0 1.8 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin PQQ PF01011.21 KIK36391.1 - 0.19 11.7 1.2 59 3.9 0.0 4.3 5 0 0 5 5 5 0 PQQ enzyme repeat Lgl_C PF08596.10 KIK36392.1 - 0.064 12.0 0.0 0.064 12.0 0.0 1.0 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal F-box-like PF12937.7 KIK36395.1 - 1.9e-09 37.3 3.7 4.9e-09 35.9 3.7 1.7 1 0 0 1 1 1 1 F-box-like Retrotran_gag_2 PF14223.6 KIK36396.1 - 4.6e-08 32.8 0.1 6e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Stork_head PF10264.9 KIK36396.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain Dynamin_N PF00350.23 KIK36397.1 - 5.7e-18 65.5 0.1 5.7e-18 65.5 0.1 2.4 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KIK36397.1 - 1.8e-05 24.8 0.2 0.014 15.4 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase Apolipoprotein PF01442.18 KIK36397.1 - 0.0018 18.2 1.4 0.0018 18.2 1.4 3.1 4 0 0 4 4 4 1 Apolipoprotein A1/A4/E domain KELK PF15796.5 KIK36397.1 - 0.0082 16.6 9.8 0.12 12.9 1.1 3.0 2 0 0 2 2 2 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase XhlA PF10779.9 KIK36397.1 - 0.03 14.5 0.1 0.03 14.5 0.1 4.2 5 0 0 5 5 5 0 Haemolysin XhlA GAS PF13851.6 KIK36397.1 - 0.031 13.6 10.1 0.22 10.9 0.6 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_16 PF13191.6 KIK36397.1 - 0.066 13.6 0.6 0.57 10.6 0.0 2.9 3 1 0 3 3 3 0 AAA ATPase domain RsgA_GTPase PF03193.16 KIK36397.1 - 0.11 12.5 0.2 0.86 9.5 0.0 2.6 3 0 0 3 3 3 0 RsgA GTPase Prefoldin PF02996.17 KIK36397.1 - 0.27 11.2 6.5 5.3 7.0 1.3 3.0 2 0 0 2 2 2 0 Prefoldin subunit Laminin_II PF06009.12 KIK36397.1 - 0.54 10.3 9.4 2.1 8.4 1.5 3.5 3 0 0 3 3 3 0 Laminin Domain II DUF2564 PF10819.8 KIK36397.1 - 0.88 10.0 3.8 0.55 10.7 0.7 2.3 2 0 0 2 2 1 0 Protein of unknown function (DUF2564) APG6_N PF17675.1 KIK36397.1 - 3.3 8.2 12.0 0.27 11.8 1.0 2.7 2 0 0 2 2 2 0 Apg6 coiled-coil region Pes-10 PF07149.11 KIK36397.1 - 4.8 6.1 9.5 9.8 5.1 9.5 1.4 1 0 0 1 1 1 0 Pes-10 AAA_23 PF13476.6 KIK36397.1 - 8.4 6.8 17.5 2 8.9 0.1 3.5 2 1 1 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 KIK36400.1 - 8.7e-77 258.1 0.0 1.2e-76 257.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArsA_ATPase PF02374.15 KIK36400.1 - 0.00027 20.2 0.0 0.00038 19.7 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_16 PF13191.6 KIK36400.1 - 0.0007 20.0 0.0 0.018 15.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KIK36400.1 - 0.01 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 KIK36400.1 - 0.013 14.5 0.1 0.02 13.9 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PhoH PF02562.16 KIK36400.1 - 0.013 14.9 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 KIK36400.1 - 0.016 14.2 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF463 PF04317.12 KIK36400.1 - 0.018 14.0 0.0 0.043 12.7 0.0 1.5 2 0 0 2 2 2 0 YcjX-like family, DUF463 AAA_18 PF13238.6 KIK36400.1 - 0.021 15.4 0.0 0.038 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KIK36400.1 - 0.023 14.7 0.0 0.071 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 KIK36400.1 - 0.028 14.5 0.0 0.04 14.0 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 KIK36400.1 - 0.044 13.5 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 KIK36400.1 - 0.045 13.7 0.1 7.7 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KIK36400.1 - 0.049 13.9 0.0 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 KIK36400.1 - 0.055 13.2 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.14 KIK36400.1 - 0.055 13.5 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 KIK36400.1 - 0.061 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 KaiC CLP1_P PF16575.5 KIK36400.1 - 0.062 13.1 0.0 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 KIK36400.1 - 0.066 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KIK36400.1 - 0.076 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.20 KIK36400.1 - 0.078 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_7 PF12775.7 KIK36400.1 - 0.079 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KIK36400.1 - 0.082 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 KIK36400.1 - 0.082 12.6 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK36400.1 - 0.099 13.0 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 KIK36400.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 KIK36400.1 - 0.14 12.2 0.0 0.4 10.8 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Cytidylate_kin PF02224.18 KIK36400.1 - 0.15 11.8 0.6 0.55 9.9 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase NACHT PF05729.12 KIK36400.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 KIK36400.1 - 0.19 11.8 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KIK36400.1 - 0.21 11.5 0.1 0.69 9.8 0.1 1.8 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.27 KIK36400.1 - 0.22 12.0 0.0 0.46 11.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Mago-bind PF09282.10 KIK36401.1 - 8.7e-14 51.1 0.7 1.3e-13 50.5 0.7 1.3 1 0 0 1 1 1 1 Mago binding DUF1640 PF07798.11 KIK36402.1 - 1.3e-40 139.2 5.7 1.6e-40 139.0 5.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) UPF0242 PF06785.11 KIK36402.1 - 0.075 13.1 2.0 0.12 12.5 2.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fzo_mitofusin PF04799.13 KIK36402.1 - 0.29 10.7 3.8 0.54 9.8 3.7 1.5 1 1 0 1 1 1 0 fzo-like conserved region TPR_10 PF13374.6 KIK36403.1 - 0.002 17.9 0.0 0.33 10.9 0.1 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK36403.1 - 0.044 13.8 0.1 3.1 8.0 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat GST_N PF02798.20 KIK36405.1 - 8.1e-13 48.5 0.0 1.6e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK36405.1 - 6.3e-10 39.1 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIK36405.1 - 1.4e-09 38.2 0.0 2.8e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK36405.1 - 2.8e-09 37.1 0.0 5.3e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIK36405.1 - 8.6e-07 29.1 0.0 1.5e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK36405.1 - 1e-05 25.5 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pet191_N PF10203.9 KIK36407.1 - 1.6e-26 92.4 6.5 1.9e-26 92.2 6.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 GCV_T PF01571.21 KIK36408.1 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain ACPS PF01648.20 KIK36409.1 - 3.7e-14 52.8 0.0 4.2e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily WD40 PF00400.32 KIK36410.1 - 2.2e-40 135.9 24.3 3.9e-05 24.3 0.0 10.8 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36410.1 - 7.4e-12 45.4 4.2 0.98 9.8 0.0 7.8 5 3 3 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain DEAD PF00270.29 KIK36411.1 - 2.5e-17 63.2 0.0 4.9e-17 62.2 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK36411.1 - 2.9e-07 30.8 0.0 6.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dimer_Tnp_hAT PF05699.14 KIK36412.1 - 2.4e-12 46.4 0.0 2.5e-12 46.4 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Spc7_N PF15402.6 KIK36414.1 - 0.087 11.1 0.0 0.1 10.8 0.0 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF1593 PF07632.11 KIK36414.1 - 0.14 11.5 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) DUF4939 PF16297.5 KIK36416.1 - 1.8e-06 27.8 0.0 3.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Asp_protease_2 PF13650.6 KIK36417.1 - 0.005 17.5 0.0 0.0051 17.4 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KIK36417.1 - 0.0064 16.3 0.0 0.0066 16.2 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KIK36417.1 - 0.11 13.0 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease ThiG PF05690.14 KIK36418.1 - 0.0042 16.4 0.0 0.0043 16.4 0.0 1.0 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DUF1631 PF07793.11 KIK36419.1 - 0.12 10.8 0.1 0.12 10.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) CxC2 PF18803.1 KIK36420.1 - 1e-07 32.1 0.1 1.8e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases RVT_1 PF00078.27 KIK36421.1 - 0.042 13.4 0.0 0.042 13.4 0.0 1.0 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) EIF_2_alpha PF07541.12 KIK36423.1 - 3.2e-35 120.7 0.0 5.7e-35 119.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KIK36423.1 - 4.2e-13 49.4 0.8 7.7e-13 48.6 0.8 1.5 1 0 0 1 1 1 1 S1 RNA binding domain ETF_QO PF05187.13 KIK36424.1 - 1.1e-38 131.5 0.0 1.9e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 KIK36424.1 - 3.5e-08 33.4 0.5 9.6e-06 25.4 0.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK36424.1 - 2.1e-07 31.0 0.0 6.7e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK36424.1 - 8.5e-05 21.9 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIK36424.1 - 0.00021 20.7 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KIK36424.1 - 0.00022 20.5 0.5 0.001 18.2 0.5 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KIK36424.1 - 0.00044 19.6 0.1 0.00066 19.0 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK36424.1 - 0.00048 19.4 0.0 0.0022 17.3 0.0 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KIK36424.1 - 0.00067 18.5 0.3 0.001 17.9 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 KIK36424.1 - 0.0013 18.8 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KIK36424.1 - 0.0077 15.1 0.1 3.4 6.4 0.2 2.7 3 0 0 3 3 3 2 Tryptophan halogenase Lycopene_cycl PF05834.12 KIK36424.1 - 0.0092 15.1 0.1 0.014 14.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 KIK36424.1 - 0.011 16.3 0.0 7.5 7.2 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.7 KIK36424.1 - 0.027 15.0 0.4 0.059 14.0 0.4 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain K_oxygenase PF13434.6 KIK36424.1 - 0.043 12.9 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_6 PF12837.7 KIK36424.1 - 1.4 9.1 3.7 1.9 8.7 0.9 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain MFS_2 PF13347.6 KIK36425.1 - 3.3e-05 22.6 25.1 0.00082 18.0 25.1 2.9 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.7 KIK36425.1 - 0.0027 16.6 3.9 0.0068 15.3 3.9 1.7 1 1 0 1 1 1 1 MFS_1 like family DUF1688 PF07958.11 KIK36426.1 - 7.8e-166 552.0 0.0 8.8e-166 551.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Q_salvage PF10343.9 KIK36426.1 - 0.0036 16.9 0.0 0.01 15.4 0.0 1.7 2 0 0 2 2 2 1 Potential Queuosine, Q, salvage protein family PHP PF02811.19 KIK36428.1 - 1.3e-12 48.4 0.1 2e-12 47.8 0.1 1.3 1 0 0 1 1 1 1 PHP domain Spo7 PF03907.13 KIK36430.1 - 4.8e-38 130.8 1.1 1.4e-37 129.4 1.1 1.6 1 1 0 1 1 1 1 Spo7-like protein Tmemb_18A PF09771.9 KIK36430.1 - 0.018 15.4 0.5 0.091 13.2 0.5 1.9 1 1 0 1 1 1 0 Transmembrane protein 188 DUF5542 PF17696.1 KIK36430.1 - 1.4 9.1 5.3 25 5.1 0.1 3.2 3 1 0 3 3 3 0 Family of unknown function (DUF5542) DUF3684 PF12449.8 KIK36432.1 - 0 1166.3 0.0 0 1166.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) p450 PF00067.22 KIK36433.1 - 4.9e-27 94.8 0.0 1.2e-26 93.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 ESCRT-II PF05871.12 KIK36434.1 - 9e-11 42.2 0.0 1.1e-10 41.9 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit CK_II_beta PF01214.18 KIK36435.1 - 0.017 15.0 1.9 0.017 15.0 1.9 1.9 2 0 0 2 2 2 0 Casein kinase II regulatory subunit FYVE_2 PF02318.16 KIK36435.1 - 1.8 8.8 11.2 2.5 8.3 2.8 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger Herpes_TAF50 PF03326.13 KIK36436.1 - 0.05 12.3 1.8 0.052 12.2 1.8 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Plavaka PF18759.1 KIK36439.1 - 8.2e-36 123.9 0.0 1.4e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase PDDEXK_1 PF12705.7 KIK36439.1 - 0.0067 16.4 0.4 0.014 15.4 0.0 1.7 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily SDA1 PF05285.12 KIK36439.1 - 0.1 12.0 9.4 0.16 11.3 9.4 1.3 1 0 0 1 1 1 0 SDA1 ArgoL2 PF16488.5 KIK36441.1 - 1.7e-07 31.5 0.0 2.2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Argonaute linker 2 domain 14-3-3 PF00244.20 KIK36442.1 - 1.9e-66 223.7 1.7 4.5e-66 222.5 1.7 1.5 1 1 0 1 1 1 1 14-3-3 protein CDC48_N PF02359.18 KIK36444.1 - 7.6e-07 29.2 0.0 2.2e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.17 KIK36444.1 - 0.0023 17.7 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 tRNA_SAD PF07973.14 KIK36446.1 - 1.9e-11 43.9 0.0 3.7e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 KIK36446.1 - 1.6e-05 23.6 0.0 2.2e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) Plavaka PF18759.1 KIK36451.1 - 1.1e-36 126.8 0.0 3.2e-36 125.2 0.0 1.8 1 0 0 1 1 1 1 Plavaka transposase Aft1_HRA PF11786.8 KIK36452.1 - 1.2e-21 76.8 8.0 1.2e-21 76.8 8.0 3.0 3 0 0 3 3 3 1 Aft1 HRA domain Robl_LC7 PF03259.17 KIK36452.1 - 0.16 11.7 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 Roadblock/LC7 domain Dicty_REP PF05086.12 KIK36452.1 - 3.9 5.3 5.0 6.1 4.7 5.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SH3_2 PF07653.17 KIK36456.1 - 0.016 14.9 0.0 0.027 14.1 0.0 1.4 1 1 0 1 1 1 0 Variant SH3 domain RabGAP-TBC PF00566.18 KIK36457.1 - 2.3e-34 118.9 0.0 4e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain zf-RING_UBOX PF13445.6 KIK36458.1 - 0.043 13.8 1.3 0.082 12.9 1.3 1.5 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KIK36458.1 - 0.072 13.4 4.6 3.8 7.9 4.7 2.1 1 1 1 2 2 2 0 Ring finger domain zf-RING_11 PF17123.5 KIK36458.1 - 0.12 12.1 1.7 4.2 7.2 1.7 2.3 1 1 0 1 1 1 0 RING-like zinc finger Plavaka PF18759.1 KIK36461.1 - 3.9e-48 164.3 0.0 6e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase ACOX PF01756.19 KIK36466.1 - 2.6e-36 124.9 0.0 1.4e-35 122.5 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KIK36466.1 - 4.2e-13 49.9 0.0 7.4e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KIK36466.1 - 9.1e-08 32.2 0.0 2.2e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Glyco_hydro_79C PF16862.5 KIK36467.1 - 2e-17 64.0 0.0 1.1e-16 61.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain RELT PF12606.8 KIK36468.1 - 3.5 6.7 8.5 8.8 5.4 8.5 1.8 1 1 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 La PF05383.17 KIK36470.1 - 5.1e-22 77.7 0.0 1.2e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KIK36470.1 - 2e-07 30.7 0.1 5.3e-07 29.4 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIK36470.1 - 2.3e-05 24.4 2.1 0.00037 20.5 0.0 2.7 2 1 0 2 2 2 1 RNA binding motif eIF-3_zeta PF05091.12 KIK36470.1 - 0.0012 17.9 0.4 0.0012 17.9 0.4 1.7 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1330 PF07045.11 KIK36470.1 - 0.034 14.5 0.0 0.089 13.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) adh_short PF00106.25 KIK36472.1 - 5.3e-32 110.9 0.1 6.7e-26 91.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK36472.1 - 1.4e-21 77.2 0.0 8.2e-20 71.4 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK36472.1 - 1.1e-06 28.7 0.0 1.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK36472.1 - 3.6e-05 23.3 0.1 0.0001 21.9 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KIK36472.1 - 0.002 18.4 0.1 0.0034 17.6 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KIK36472.1 - 0.0028 17.1 0.1 0.16 11.3 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 KIK36472.1 - 0.09 12.8 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 KIK36472.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TCR_zetazeta PF11628.8 KIK36474.1 - 0.00033 20.3 0.1 0.0007 19.2 0.1 1.6 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 zeta chain Peptidase_C41 PF05417.11 KIK36474.1 - 0.035 13.9 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Hepatitis E cysteine protease MbtH PF03621.13 KIK36474.1 - 2.5 7.6 4.6 0.54 9.7 0.1 2.0 2 0 0 2 2 2 0 MbtH-like protein NAD_binding_2 PF03446.15 KIK36477.1 - 2.9e-05 24.3 0.0 6.3e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KIK36477.1 - 0.0024 18.4 0.0 0.0045 17.5 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KIK36477.1 - 0.0076 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KIK36477.1 - 0.08 12.8 0.4 0.14 12.1 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KIK36477.1 - 0.11 12.1 0.2 0.18 11.5 0.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA zf-RING_2 PF13639.6 KIK36479.1 - 4e-10 39.9 5.6 2.4e-09 37.4 5.6 2.0 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KIK36479.1 - 1.7e-09 37.8 2.5 2.8e-09 37.1 2.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KIK36479.1 - 6.1e-08 32.3 0.9 4.4e-06 26.3 0.3 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KIK36479.1 - 9.5e-08 32.0 0.7 1.5e-07 31.4 0.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KIK36479.1 - 1e-06 28.5 0.8 1.8e-06 27.7 0.8 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK36479.1 - 1.2e-06 28.3 0.7 2.2e-06 27.5 0.7 1.4 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KIK36479.1 - 4.5e-06 26.4 3.3 2.4e-05 24.1 1.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK36479.1 - 6.3e-05 22.9 5.8 0.00028 20.9 6.0 2.0 1 1 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KIK36479.1 - 0.00021 20.8 0.5 0.00021 20.8 0.5 1.7 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KIK36479.1 - 0.0017 18.1 1.5 0.0078 16.0 0.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KIK36479.1 - 0.0037 17.0 2.0 0.031 14.1 2.0 2.1 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 KIK36479.1 - 0.0041 17.3 2.1 0.025 14.8 2.1 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain Prok-RING_4 PF14447.6 KIK36479.1 - 0.013 15.4 0.7 0.013 15.4 0.7 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.7 KIK36479.1 - 0.013 15.6 3.2 0.02 15.0 0.6 2.2 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4_4 PF15227.6 KIK36479.1 - 0.016 15.3 1.4 0.016 15.3 1.4 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KIK36479.1 - 0.067 13.0 0.9 0.17 11.7 0.2 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KIK36479.1 - 1.1 9.7 4.6 0.34 11.2 0.9 1.9 2 0 0 2 2 2 0 RING-like domain ubiquitin PF00240.23 KIK36480.1 - 3.9e-55 183.5 0.1 4e-24 84.1 0.1 3.1 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 KIK36480.1 - 3e-26 91.0 1.6 1.5e-13 50.3 0.1 3.2 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KIK36480.1 - 6e-12 45.3 0.1 3.6e-07 30.0 0.0 2.6 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KIK36480.1 - 5e-08 33.4 0.1 0.00021 21.8 0.1 2.9 2 1 1 3 3 3 2 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KIK36480.1 - 1.1e-06 28.6 1.2 2.4 8.3 0.1 4.9 3 2 1 4 4 4 2 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KIK36480.1 - 1.8e-06 28.2 0.5 0.036 14.4 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-like domain Ubiquitin_2 PF14560.6 KIK36480.1 - 2.1e-05 24.9 1.4 0.13 12.8 0.1 3.7 3 3 0 3 3 3 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIK36480.1 - 0.002 18.2 0.0 0.73 10.0 0.0 3.3 2 1 1 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like USP7_C2 PF14533.6 KIK36480.1 - 0.0026 17.5 0.2 5.7 6.6 0.0 3.0 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal YukD PF08817.10 KIK36480.1 - 0.0054 17.4 0.1 0.73 10.6 0.0 3.2 3 0 0 3 3 3 1 WXG100 protein secretion system (Wss), protein YukD UN_NPL4 PF11543.8 KIK36480.1 - 0.018 15.5 0.1 7.8 7.1 0.0 2.6 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 Sde2_N_Ubi PF13019.6 KIK36480.1 - 0.052 13.4 0.2 0.28 11.0 0.0 2.2 3 0 0 3 3 3 0 Silencing defective 2 N-terminal ubiquitin domain AAA_2 PF07724.14 KIK36482.1 - 1.4e-45 155.5 0.0 7.5e-43 146.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KIK36482.1 - 3e-28 97.8 2.8 3e-28 97.8 2.8 2.3 2 0 0 2 2 1 1 AAA lid domain AAA PF00004.29 KIK36482.1 - 1.2e-25 90.4 0.0 2.8e-13 50.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KIK36482.1 - 1.6e-18 66.6 0.5 7.2e-18 64.4 0.5 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KIK36482.1 - 4.7e-14 52.5 0.1 1.3e-06 28.5 0.0 3.8 2 2 1 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIK36482.1 - 1.3e-12 48.5 3.8 1.2e-05 25.8 0.2 4.1 3 1 0 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 KIK36482.1 - 5.6e-11 42.4 0.0 1.3e-05 25.0 0.0 3.4 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_22 PF13401.6 KIK36482.1 - 8.3e-10 39.1 0.1 0.0034 17.7 0.0 3.5 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.13 KIK36482.1 - 1.5e-07 30.9 0.0 0.0014 18.0 0.0 3.0 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_18 PF13238.6 KIK36482.1 - 2.4e-07 31.3 0.4 0.038 14.6 0.0 3.7 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 KIK36482.1 - 2.7e-07 30.5 0.0 0.02 14.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 KIK36482.1 - 5.3e-07 29.3 0.0 0.0046 16.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region RNA_helicase PF00910.22 KIK36482.1 - 9.1e-07 29.2 0.0 0.063 13.7 0.0 3.0 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.12 KIK36482.1 - 1.7e-06 27.9 0.2 0.074 12.8 0.0 3.8 4 0 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KIK36482.1 - 1.4e-05 25.3 0.0 0.032 14.4 0.0 3.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KIK36482.1 - 2.1e-05 24.5 0.7 0.0092 15.9 0.0 3.2 3 0 0 3 3 3 1 NACHT domain Mg_chelatase PF01078.21 KIK36482.1 - 3e-05 23.5 0.3 0.21 11.0 0.0 3.1 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KIK36482.1 - 4.1e-05 23.6 0.0 0.5 10.4 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Torsin PF06309.11 KIK36482.1 - 4.1e-05 23.7 0.0 0.0003 20.9 0.0 2.2 2 0 0 2 2 2 1 Torsin Zeta_toxin PF06414.12 KIK36482.1 - 4.2e-05 22.9 0.0 0.25 10.6 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin Sigma54_activ_2 PF14532.6 KIK36482.1 - 5.6e-05 23.3 0.0 0.38 10.9 0.0 2.9 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.6 KIK36482.1 - 0.00039 20.2 0.0 0.81 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KIK36482.1 - 0.0004 20.4 0.0 0.024 14.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KIK36482.1 - 0.00043 20.1 0.4 5.4 6.9 0.0 4.5 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KIK36482.1 - 0.00049 20.1 2.0 1.4 8.8 0.0 4.4 4 1 1 5 5 5 1 ATPase domain predominantly from Archaea APS_kinase PF01583.20 KIK36482.1 - 0.00054 19.9 0.0 0.0092 15.9 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_30 PF13604.6 KIK36482.1 - 0.00071 19.4 2.7 2.6 7.7 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.6 KIK36482.1 - 0.00075 20.1 0.6 0.075 13.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.13 KIK36482.1 - 0.00083 18.6 0.1 0.39 9.8 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 KIK36482.1 - 0.0012 19.1 5.3 0.16 12.2 0.1 3.5 3 1 0 3 3 3 1 AAA domain PhoH PF02562.16 KIK36482.1 - 0.0013 18.2 0.1 0.33 10.4 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.15 KIK36482.1 - 0.0014 18.6 0.0 0.075 13.0 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 KIK36482.1 - 0.0017 18.0 1.0 0.17 11.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.27 KIK36482.1 - 0.0034 17.9 1.5 0.58 10.7 0.0 3.1 3 1 0 3 3 2 1 ABC transporter RsgA_GTPase PF03193.16 KIK36482.1 - 0.0049 16.8 0.1 5.9 6.8 0.0 2.8 2 0 0 2 2 2 0 RsgA GTPase Rad17 PF03215.15 KIK36482.1 - 0.0053 16.7 0.0 0.43 10.5 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain Roc PF08477.13 KIK36482.1 - 0.0079 16.4 0.0 3.6 7.8 0.0 2.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 KIK36482.1 - 0.011 16.0 3.2 2.5 8.4 0.0 4.0 4 0 0 4 4 2 0 AAA domain Parvo_NS1 PF01057.17 KIK36482.1 - 0.012 14.7 0.2 1.7 7.6 0.0 2.7 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 KIK36482.1 - 0.022 14.0 1.9 4.2 6.5 0.0 3.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 KIK36482.1 - 0.025 13.7 0.5 0.11 11.5 0.0 2.4 3 0 0 3 3 3 0 Type II/IV secretion system protein DNA_pol3_delta2 PF13177.6 KIK36482.1 - 0.046 13.5 0.1 1.2 8.9 0.0 2.8 3 0 0 3 3 3 0 DNA polymerase III, delta subunit AAA_29 PF13555.6 KIK36482.1 - 0.059 13.1 0.0 3.1 7.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 KIK36482.1 - 0.07 13.0 0.1 16 5.4 0.0 2.7 2 0 0 2 2 2 0 NTPase HxlR PF01638.17 KIK36482.1 - 0.11 12.4 0.0 35 4.4 0.0 3.0 3 0 0 3 3 2 0 HxlR-like helix-turn-helix Senescence PF06911.12 KIK36482.1 - 0.17 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Senescence-associated protein SlyX PF04102.12 KIK36482.1 - 2.2 9.0 6.0 26 5.5 0.0 3.7 2 1 0 3 3 3 0 SlyX PI3K_p85B PF02192.16 KIK36483.1 - 0.08 12.7 0.2 0.2 11.4 0.2 1.6 1 0 0 1 1 1 0 PI3-kinase family, p85-binding domain WD40 PF00400.32 KIK36484.1 - 9.8e-23 80.0 0.3 0.0006 20.6 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36484.1 - 5.1e-07 29.9 0.0 0.2 12.0 0.0 4.0 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK36484.1 - 0.0022 16.8 0.0 0.0055 15.4 0.0 1.7 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK36484.1 - 0.023 13.7 0.0 9.8 5.0 0.0 3.2 1 1 3 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SNF2_N PF00176.23 KIK36485.1 - 4e-61 206.7 0.0 3.5e-60 203.6 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK36485.1 - 2.3e-19 69.8 0.0 1.2e-18 67.4 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK36485.1 - 1.8e-09 37.8 0.0 4e-08 33.4 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KIK36485.1 - 9.9e-05 21.6 0.0 0.00026 20.2 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Tom22 PF04281.13 KIK36485.1 - 0.038 13.8 1.6 0.066 13.0 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 DEAD PF00270.29 KIK36485.1 - 0.12 12.1 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase F-box PF00646.33 KIK36486.1 - 1.8e-10 40.4 1.2 4.4e-10 39.2 1.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK36486.1 - 1.1e-08 34.8 0.5 2.9e-08 33.4 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIK36486.1 - 0.085 12.7 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 F-box DUF5437 PF17505.2 KIK36487.1 - 0.099 12.7 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5437) Pkinase PF00069.25 KIK36489.1 - 1.7e-20 73.5 0.0 2e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK36489.1 - 7.7e-15 54.9 0.0 9.6e-15 54.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK36489.1 - 5.4e-06 25.4 0.0 6.9e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIK36489.1 - 1e-05 25.0 0.0 1.2e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIK36489.1 - 0.012 14.6 0.1 0.014 14.3 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KIK36489.1 - 0.056 12.7 0.0 0.056 12.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Malic_M PF03949.15 KIK36490.1 - 2.8e-88 295.5 0.0 3.6e-88 295.1 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KIK36490.1 - 5.8e-66 221.8 0.0 8.8e-66 221.2 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain RRM_1 PF00076.22 KIK36492.1 - 1.5e-33 114.4 0.0 9e-16 57.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3932 PF13068.6 KIK36492.1 - 0.01 16.1 0.0 6.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3932) RRM_7 PF16367.5 KIK36492.1 - 0.079 13.1 0.0 12 6.1 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif TENA_THI-4 PF03070.16 KIK36494.1 - 6.9e-13 48.9 1.0 9.5e-13 48.4 1.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Histone PF00125.24 KIK36495.1 - 6.3e-22 78.3 5.6 8.1e-22 78.0 4.3 1.7 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KIK36495.1 - 0.00015 22.0 0.1 0.00015 22.0 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KIK36495.1 - 0.00051 20.5 0.0 0.00091 19.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KIK36495.1 - 0.069 13.2 0.2 0.088 12.8 0.2 1.1 1 0 0 1 1 1 0 YscO-like protein Histone_H2A_C PF16211.5 KIK36496.1 - 3.4e-17 61.9 0.6 5.5e-17 61.2 0.6 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KIK36496.1 - 6.2e-16 59.0 0.0 7.7e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KIK36496.1 - 8.4e-07 29.2 0.0 1.1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ERG2_Sigma1R PF04622.12 KIK36497.1 - 1.1e-95 318.9 0.1 1.3e-95 318.7 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein CHAT PF12770.7 KIK36499.1 - 5.4e-30 104.8 0.0 1.1e-29 103.8 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK36499.1 - 5e-09 35.8 6.1 0.26 11.2 0.0 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIK36499.1 - 0.00016 21.6 2.2 4.2 7.7 0.1 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat Vta1_C PF18097.1 KIK36499.1 - 0.015 15.0 2.6 11 5.8 0.0 4.1 4 0 0 4 4 4 0 Vta1 C-terminal domain MIT PF04212.18 KIK36499.1 - 0.19 11.8 1.4 37 4.5 0.1 4.4 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 KIK36499.1 - 1.1 9.2 7.7 26 4.8 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat SPC25 PF06703.11 KIK36500.1 - 9.8e-51 171.8 0.0 1.2e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Amino_oxidase PF01593.24 KIK36501.1 - 8e-23 81.4 0.0 8e-23 81.4 0.0 1.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK36501.1 - 2.8e-08 33.9 0.0 2.8e-08 33.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK36501.1 - 0.0003 20.5 0.0 0.0003 20.5 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIK36501.1 - 0.001 18.4 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KIK36501.1 - 0.014 14.7 0.8 0.058 12.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KIK36501.1 - 0.028 13.2 0.0 0.038 12.8 0.0 1.1 1 0 0 1 1 1 0 MCRA family NAD_binding_9 PF13454.6 KIK36501.1 - 0.19 11.7 0.0 0.19 11.7 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KIK36501.1 - 0.25 10.6 0.2 8.8 5.6 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Dimer_Tnp_hAT PF05699.14 KIK36503.1 - 2.5e-14 52.8 0.0 2.7e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 KIK36506.1 - 0.016 15.1 0.0 0.017 15.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Tetraspanin PF00335.20 KIK36507.1 - 0.0068 16.1 2.2 0.017 14.8 2.2 1.6 1 1 0 1 1 1 1 Tetraspanin family Transposase_21 PF02992.14 KIK36510.1 - 1.4e-05 24.4 0.1 3.4e-05 23.2 0.1 1.6 2 0 0 2 2 2 1 Transposase family tnp2 Vma12 PF11712.8 KIK36512.1 - 0.013 15.6 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4218 PF13960.6 KIK36513.1 - 0.021 14.4 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) zf-RVT PF13966.6 KIK36514.1 - 0.00016 22.3 0.2 0.00035 21.2 0.2 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DAN PF03045.15 KIK36514.1 - 0.057 13.5 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 DAN domain MCM_OB PF17207.3 KIK36515.1 - 0.017 15.0 0.9 0.023 14.5 0.9 1.2 1 0 0 1 1 1 0 MCM OB domain zf-Di19 PF05605.12 KIK36518.1 - 0.068 13.5 2.1 0.072 13.4 0.1 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Mating_N PF12731.7 KIK36519.1 - 0.096 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Mating-type protein beta 1 NYD-SP28 PF14772.6 KIK36519.1 - 0.17 11.9 10.1 0.5 10.4 0.7 2.1 1 1 1 2 2 2 0 Sperm tail ALIX_LYPXL_bnd PF13949.6 KIK36520.1 - 0.0049 16.2 0.5 0.0069 15.7 0.5 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Fis1_TPR_N PF14852.6 KIK36523.1 - 0.0056 16.3 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat Plavaka PF18759.1 KIK36525.1 - 1.6e-29 103.2 0.2 9.3e-19 67.8 0.1 2.1 1 1 1 2 2 2 2 Plavaka transposase DENN PF02141.21 KIK36527.1 - 0.078 12.9 0.1 0.091 12.7 0.1 1.1 1 0 0 1 1 1 0 DENN (AEX-3) domain zf-RVT PF13966.6 KIK36528.1 - 0.003 18.3 0.1 0.0032 18.1 0.1 1.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase SLAC1 PF03595.17 KIK36529.1 - 0.3 10.3 18.9 0.6 9.3 9.6 2.2 2 0 0 2 2 2 0 Voltage-dependent anion channel PEX11 PF05648.14 KIK36530.1 - 4e-12 46.1 0.1 3.5e-10 39.7 0.1 2.7 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) HD PF01966.22 KIK36531.1 - 0.00015 22.0 0.2 0.00041 20.6 0.2 1.8 1 1 0 1 1 1 1 HD domain Zip PF02535.22 KIK36532.1 - 7.6e-39 133.8 21.4 6.3e-37 127.5 21.4 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter GST_C_5 PF16865.5 KIK36532.1 - 0.13 12.8 0.1 0.36 11.4 0.1 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glug PF07581.12 KIK36532.1 - 0.35 11.4 4.1 0.23 12.0 1.1 2.3 2 0 0 2 2 2 0 The GLUG motif NUDIX PF00293.28 KIK36533.1 - 3.9e-12 46.3 0.2 4.6e-12 46.1 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain WD40 PF00400.32 KIK36537.1 - 2e-19 69.5 8.3 1.4e-10 41.5 0.2 3.0 3 1 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36537.1 - 1.4e-07 31.7 0.0 0.014 15.7 0.0 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK36537.1 - 1.3e-06 27.6 0.0 0.0068 15.4 0.0 2.1 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK36537.1 - 8.2e-05 22.4 4.4 0.57 10.2 0.0 3.7 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK36537.1 - 0.14 10.4 0.0 8.7 4.5 0.0 2.0 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF5643 PF18705.1 KIK36537.1 - 0.19 11.7 0.0 6 6.9 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5643) Methyltransf_23 PF13489.6 KIK36538.1 - 0.00013 21.9 0.0 0.00022 21.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK36538.1 - 0.00072 20.3 0.0 0.0019 18.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK36538.1 - 0.0068 16.2 0.1 0.1 12.4 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK36538.1 - 0.061 14.0 0.0 11 6.8 0.1 2.4 2 0 0 2 2 2 0 Methyltransferase domain DUF3640 PF12342.8 KIK36538.1 - 0.11 12.3 2.3 0.36 10.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3640) MTS PF05175.14 KIK36538.1 - 0.22 11.0 0.0 0.5 9.9 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain HLH PF00010.26 KIK36539.1 - 1.3e-05 25.1 0.0 5.2e-05 23.1 0.0 2.1 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain CytochromB561_N PF09786.9 KIK36539.1 - 0.17 10.8 11.9 0.21 10.5 11.9 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Macoilin PF09726.9 KIK36539.1 - 2.9 6.3 6.7 3.4 6.1 6.7 1.1 1 0 0 1 1 1 0 Macoilin family THUMP PF02926.17 KIK36540.1 - 1.1e-09 38.5 0.1 5.8e-09 36.2 0.1 2.2 1 1 0 1 1 1 1 THUMP domain Adipokin_hormo PF06377.11 KIK36540.1 - 0.052 13.9 0.4 13 6.2 0.1 2.5 2 0 0 2 2 2 0 Adipokinetic hormone YedD PF13987.6 KIK36541.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 YedD-like protein F-box-like PF12937.7 KIK36543.1 - 0.0072 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 F-box-like TPR_1 PF00515.28 KIK36546.1 - 0.01 15.7 0.1 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK36546.1 - 0.015 15.4 0.0 4.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 KIK36546.1 - 0.028 14.5 0.0 6.9 6.7 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) WD40 PF00400.32 KIK36547.1 - 3.5e-35 119.4 13.4 1.1e-05 26.0 1.0 7.3 6 1 1 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36547.1 - 2.8e-17 62.8 0.1 0.013 15.7 0.0 6.0 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK36547.1 - 1.6e-07 31.4 0.0 0.0014 18.6 0.0 3.0 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK36547.1 - 7.3e-05 21.9 0.3 0.007 15.4 0.1 3.2 1 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KIK36547.1 - 0.0025 16.8 0.1 0.43 9.4 0.1 2.4 2 0 0 2 2 2 2 Partner and localizer of BRCA2 WD40 domain PD40 PF07676.12 KIK36547.1 - 0.0046 16.9 0.0 16 5.5 0.0 3.7 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat SR-25 PF10500.9 KIK36548.1 - 1.3 8.6 4.8 1.7 8.2 4.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Glyco_hydro_3_C PF01915.22 KIK36550.1 - 5.9e-50 170.1 0.0 1.1e-49 169.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIK36550.1 - 5.6e-38 131.1 0.1 1.1e-37 130.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIK36550.1 - 1.6e-19 69.8 0.0 3e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain FAD_binding_1 PF00667.20 KIK36551.1 - 2.9e-37 128.4 0.0 4.4e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KIK36551.1 - 2.2e-28 99.3 0.0 3.6e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KIK36551.1 - 1.7e-11 44.7 0.1 3.3e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KIK36551.1 - 0.037 14.3 0.0 0.077 13.2 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain DUF3638 PF12340.8 KIK36552.1 - 7e-89 297.0 1.8 1.3e-88 296.2 1.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KIK36552.1 - 2e-16 59.1 0.1 4.9e-16 57.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) T4SS PF07996.11 KIK36552.1 - 0.33 11.3 2.0 2.7 8.4 0.1 2.5 2 0 0 2 2 2 0 Type IV secretion system proteins KDZ PF18758.1 KIK36557.1 - 1e-60 205.1 0.0 1.6e-60 204.5 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase FTCD_C PF04961.12 KIK36557.1 - 0.031 14.1 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase DUF1292 PF06949.11 KIK36557.1 - 0.07 14.1 4.3 0.22 12.5 4.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1292) EcoRII-C PF09019.11 KIK36557.1 - 0.074 13.1 0.2 0.074 13.1 0.2 2.1 3 0 0 3 3 3 0 EcoRII C terminal Meth_synt_2 PF01717.18 KIK36558.1 - 6e-19 68.5 0.0 9.6e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain AMP-binding PF00501.28 KIK36558.1 - 3.3e-07 29.3 0.0 5.5e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ACC_central PF08326.12 KIK36558.1 - 1.6e-06 26.7 0.0 2.1e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region DEAD PF00270.29 KIK36561.1 - 1.6e-05 24.8 0.0 1.7e-05 24.7 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBD_Tnp_Hermes PF10683.9 KIK36564.1 - 0.0082 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Hermes transposase DNA-binding domain DUF2142 PF09913.9 KIK36566.1 - 0.0091 14.9 0.0 0.0099 14.8 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2142) MF_alpha_N PF05436.11 KIK36566.1 - 0.084 12.8 0.3 0.095 12.6 0.3 1.1 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Thioesterase PF00975.20 KIK36568.1 - 3e-08 34.1 0.0 7.6e-07 29.5 0.0 2.1 2 0 0 2 2 2 2 Thioesterase domain GrpE PF01025.19 KIK36571.1 - 0.0051 16.5 0.0 0.0078 15.9 0.0 1.2 1 0 0 1 1 1 1 GrpE RYDR_ITPR PF01365.21 KIK36571.1 - 0.1 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 RIH domain Plavaka PF18759.1 KIK36572.1 - 7.7e-36 123.9 0.0 1.5e-35 123.0 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase DUF2630 PF10944.8 KIK36575.1 - 0.095 13.2 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) Tankyrase_bdg_C PF15327.6 KIK36576.1 - 0.029 14.8 0.1 0.041 14.3 0.1 1.2 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain DUF2514 PF10721.9 KIK36576.1 - 0.36 10.9 7.7 0.62 10.1 7.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) IL8 PF00048.20 KIK36577.1 - 0.019 15.1 0.5 0.035 14.2 0.5 1.5 1 0 0 1 1 1 0 Small cytokines (intecrine/chemokine), interleukin-8 like Phage_int_SAM_1 PF02899.17 KIK36578.1 - 0.035 14.4 0.0 0.12 12.7 0.0 1.7 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain PIF1 PF05970.14 KIK36580.1 - 3.1e-19 69.4 0.0 3.4e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase PIF1 PF05970.14 KIK36581.1 - 8.6e-33 114.0 0.0 9.7e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.15 KIK36581.1 - 0.02 14.9 0.0 0.022 14.8 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KIK36581.1 - 0.026 14.2 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KIK36581.1 - 0.032 14.7 0.1 0.049 14.1 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KIK36581.1 - 0.048 13.4 0.2 0.065 13.0 0.2 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.11 KIK36581.1 - 0.084 13.0 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Torsin Zeta_toxin PF06414.12 KIK36581.1 - 0.087 12.1 0.0 0.14 11.4 0.0 1.3 1 1 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 KIK36581.1 - 0.11 12.9 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KIK36581.1 - 0.17 12.4 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Helitron_like_N PF14214.6 KIK36582.1 - 3.2e-28 99.3 0.0 3.5e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus zf-DNL PF05180.12 KIK36583.1 - 0.088 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 DNL zinc finger WD40 PF00400.32 KIK36584.1 - 9.8e-15 54.7 0.3 1.8e-06 28.5 0.1 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36584.1 - 7.5e-07 29.4 0.0 0.00085 19.6 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK36584.1 - 0.00042 19.1 0.0 0.2 10.3 0.0 2.0 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK36584.1 - 0.0097 14.9 0.0 0.32 9.9 0.0 2.0 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK36584.1 - 0.031 13.6 0.0 0.7 9.2 0.0 2.0 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK36584.1 - 0.047 13.0 0.0 0.3 10.4 0.0 1.9 2 0 0 2 2 2 0 WD40-like domain Nucleoporin_N PF08801.11 KIK36584.1 - 0.15 10.8 0.0 2.7 6.7 0.0 1.9 1 1 1 2 2 2 0 Nup133 N terminal like DUF5541 PF17695.1 KIK36585.1 - 0.073 13.5 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5541) Cu-oxidase PF00394.22 KIK36586.1 - 1.5e-43 148.6 0.1 1.4e-38 132.5 0.0 2.2 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK36586.1 - 9.4e-38 129.0 0.0 2.1e-37 127.9 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase TPR_10 PF13374.6 KIK36590.1 - 5e-15 54.8 9.9 0.0059 16.4 0.5 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIK36590.1 - 3.6e-07 30.4 8.6 0.82 10.0 0.2 6.0 4 2 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIK36590.1 - 0.0015 18.2 2.0 2.7 7.8 0.1 4.2 5 0 0 5 5 5 2 TPR repeat MIT PF04212.18 KIK36590.1 - 0.0035 17.4 0.6 5.8 7.1 0.4 3.1 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 KIK36590.1 - 0.01 15.9 4.8 2.6 8.4 0.1 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIK36590.1 - 0.011 16.1 1.7 10 6.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK36590.1 - 0.016 15.2 6.7 7.9 6.8 0.1 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK36590.1 - 0.043 13.7 6.5 3.1 7.8 0.1 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat FRB_dom PF08771.11 KIK36590.1 - 0.13 12.7 0.5 52 4.3 0.0 3.6 4 0 0 4 4 4 0 FKBP12-rapamycin binding domain TPR_8 PF13181.6 KIK36590.1 - 0.14 12.4 0.0 30 5.2 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat CHAT PF12770.7 KIK36591.1 - 2.6e-28 99.3 0.4 6.9e-28 97.9 0.0 1.8 2 1 0 2 2 2 1 CHAT domain Zeta_toxin PF06414.12 KIK36591.1 - 0.0057 16.0 0.4 0.014 14.7 0.1 1.8 2 0 0 2 2 2 1 Zeta toxin Peptidase_M3 PF01432.20 KIK36592.1 - 5.5e-135 451.2 0.0 7.2e-135 450.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KIK36592.1 - 0.082 12.5 0.2 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Usp PF00582.26 KIK36593.1 - 1.7e-20 74.0 1.4 2.5e-20 73.4 0.0 2.0 2 0 0 2 2 2 1 Universal stress protein family Acetyltransf_CG PF14542.6 KIK36593.1 - 0.012 15.8 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Alpha_GJ PF03229.13 KIK36593.1 - 0.043 14.4 0.3 0.096 13.2 0.3 1.6 1 0 0 1 1 1 0 Alphavirus glycoprotein J MFS_1 PF07690.16 KIK36594.1 - 1.9e-13 50.1 39.8 1.9e-13 50.1 39.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIK36594.1 - 7.5e-12 45.2 8.6 7.5e-12 45.2 8.6 3.2 3 1 1 4 4 4 1 Ion channel regulatory protein UNC-93 FixQ PF05545.11 KIK36594.1 - 7.5 6.6 8.7 1.3 9.1 2.4 3.2 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ WD40 PF00400.32 KIK36595.1 - 7e-06 26.7 0.0 0.00058 20.6 0.0 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF4470 PF14737.6 KIK36595.1 - 0.081 13.1 0.1 0.13 12.4 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4470) ParBc_2 PF08857.11 KIK36596.1 - 0.061 13.4 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Putative ParB-like nuclease SOG2 PF10428.9 KIK36598.1 - 0.081 12.1 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein WD40 PF00400.32 KIK36600.1 - 7.1e-06 26.7 2.6 3 8.8 0.0 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36600.1 - 0.0062 16.8 0.0 4.6 7.6 0.0 3.9 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain VWA PF00092.28 KIK36604.1 - 2.8e-11 44.0 0.0 5.2e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIK36604.1 - 6e-09 36.5 0.0 2e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain Integrin_beta PF00362.18 KIK36604.1 - 0.0036 17.0 0.0 0.041 13.5 0.0 2.1 1 1 1 2 2 2 1 Integrin beta chain VWA domain AstB PF04996.12 KIK36604.1 - 0.1 11.3 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Succinylarginine dihydrolase SAM_3 PF18016.1 KIK36604.1 - 0.16 11.8 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PCuAC PF04314.13 KIK36604.1 - 0.16 11.8 0.1 23 4.8 0.0 2.6 2 0 0 2 2 2 0 Copper chaperone PCu(A)C Amino_oxidase PF01593.24 KIK36606.1 - 3e-45 155.3 0.0 5.2e-45 154.6 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK36606.1 - 9.4e-10 38.6 0.2 4.5e-09 36.4 0.0 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIK36606.1 - 0.00039 19.3 0.1 0.22 10.2 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 KIK36606.1 - 0.0036 16.6 0.5 0.023 13.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK36606.1 - 0.0077 16.8 0.4 2.7 8.6 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIK36606.1 - 0.011 15.0 0.2 0.017 14.4 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KIK36606.1 - 0.19 10.9 0.0 7.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2722 PF10846.8 KIK36608.1 - 0.0013 17.7 0.3 0.0015 17.6 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) IL3Ra_N PF18611.1 KIK36608.1 - 0.055 13.5 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 IL-3 receptor alpha chain N-terminal domain O-antigen_lig PF13425.6 KIK36608.1 - 0.14 10.9 0.0 0.16 10.7 0.0 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF3094 PF11293.8 KIK36614.1 - 0.019 14.7 0.3 0.032 13.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) Rtt106_N PF18215.1 KIK36614.1 - 0.078 12.7 0.1 2.6 7.8 0.0 2.4 1 1 1 2 2 2 0 Histone chaperone Rtt106 N-terminal domain Metallophos PF00149.28 KIK36615.1 - 1.5e-07 32.1 0.1 2.4e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIK36615.1 - 0.0021 18.3 0.0 0.0026 18.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF1441 PF07278.11 KIK36617.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1441) DHHC PF01529.20 KIK36617.1 - 6.7 6.8 14.8 4.7 7.3 9.4 2.3 1 1 1 2 2 2 0 DHHC palmitoyltransferase CcmF_C PF16327.5 KIK36619.1 - 0.23 10.7 3.0 0.32 10.2 2.8 1.4 1 1 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal PIG-Y PF15159.6 KIK36619.1 - 0.87 10.6 5.6 0.54 11.2 2.8 2.0 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y PIGA PF08288.12 KIK36620.1 - 5.4e-36 123.1 0.2 1.5e-35 121.6 0.2 1.8 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 KIK36620.1 - 8.6e-26 90.9 1.8 2.4e-25 89.5 1.8 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KIK36620.1 - 5.5e-22 78.1 0.0 9.6e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIK36620.1 - 2.7e-20 73.1 0.0 6.8e-20 71.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIK36620.1 - 1.7e-12 48.1 0.2 3.7e-12 47.0 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KIK36620.1 - 0.001 19.4 0.0 0.0025 18.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 WW PF00397.26 KIK36622.1 - 8e-08 32.2 4.2 2e-07 31.0 4.2 1.7 1 0 0 1 1 1 1 WW domain UNC-50 PF05216.13 KIK36623.1 - 4.4e-67 225.9 12.9 6.7e-67 225.3 12.9 1.2 1 0 0 1 1 1 1 UNC-50 family Metallophos PF00149.28 KIK36623.1 - 3.8e-36 125.5 0.1 6.4e-36 124.8 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MgtE PF01769.16 KIK36623.1 - 0.55 10.6 6.6 1.2 9.6 0.6 2.5 2 1 0 2 2 2 0 Divalent cation transporter MFS_1 PF07690.16 KIK36624.1 - 0.00029 19.9 18.7 0.00041 19.4 18.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-H2C2_5 PF13909.6 KIK36625.1 - 2.5e-09 36.7 4.8 0.00038 20.2 0.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIK36625.1 - 4.5e-05 23.7 7.1 0.077 13.5 1.3 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK36625.1 - 0.00025 21.3 0.4 0.00025 21.3 0.4 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK36625.1 - 0.01 16.6 6.8 0.49 11.4 0.8 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger OrsD PF12013.8 KIK36625.1 - 0.4 11.1 3.1 10 6.6 0.1 2.4 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D PqqA PF08042.11 KIK36629.1 - 0.18 11.9 0.3 0.18 11.9 0.3 2.0 2 0 0 2 2 2 0 PqqA family DUF3551 PF12071.8 KIK36631.1 - 0.0069 16.4 3.0 0.0077 16.3 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3551) Sdh_cyt PF01127.22 KIK36633.1 - 7.5e-09 35.7 1.6 8.3e-09 35.5 1.6 1.0 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit EGF_MSP1_1 PF12946.7 KIK36636.1 - 0.22 11.6 1.9 1.3 9.2 0.7 2.3 2 0 0 2 2 2 0 MSP1 EGF domain 1 WD40 PF00400.32 KIK36638.1 - 6.4e-45 150.2 10.7 9.4e-11 42.1 1.1 5.1 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36638.1 - 7.7e-15 55.0 0.0 0.014 15.7 0.0 4.4 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK36638.1 - 1e-13 51.0 0.0 0.0085 15.1 0.0 4.2 4 0 0 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 KIK36638.1 - 5e-08 33.5 0.1 1.6e-07 31.9 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain PD40 PF07676.12 KIK36638.1 - 4.8e-06 26.4 8.8 0.77 9.8 0.1 5.2 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat NACHT PF05729.12 KIK36638.1 - 1.4e-05 25.1 0.0 4e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 NACHT domain eIF2A PF08662.11 KIK36638.1 - 0.0006 19.7 0.0 0.0042 17.0 0.0 2.0 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Parvo_NS1 PF01057.17 KIK36638.1 - 0.035 13.2 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.29 KIK36638.1 - 0.04 14.3 0.0 0.14 12.5 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNaseH_like PF04308.12 KIK36638.1 - 0.054 13.4 0.2 0.16 11.9 0.1 1.8 1 1 1 2 2 2 0 Ribonuclease H-like RNA_helicase PF00910.22 KIK36638.1 - 0.089 13.2 0.0 0.3 11.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.20 KIK36638.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 KIK36638.1 - 0.13 12.5 0.0 0.5 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Cuticle_4 PF15955.5 KIK36638.1 - 0.38 11.5 3.7 27 5.5 0.9 4.2 5 0 0 5 5 5 0 Cuticle protein ADH_N_2 PF16884.5 KIK36639.1 - 1.7e-18 66.5 0.2 3.5e-18 65.5 0.0 1.6 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KIK36639.1 - 3.8e-17 62.5 0.3 5.8e-17 61.9 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK36639.1 - 7.7e-05 23.7 0.0 0.00016 22.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KIK36639.1 - 0.066 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DASH_Ask1 PF08655.10 KIK36639.1 - 0.17 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Ask1 Plavaka PF18759.1 KIK36640.1 - 1.5e-31 109.8 0.3 4.7e-31 108.2 0.0 1.9 2 0 0 2 2 2 1 Plavaka transposase zf-C2H2_4 PF13894.6 KIK36640.1 - 0.53 11.3 2.2 2.6 9.1 2.2 2.3 1 0 0 1 1 1 0 C2H2-type zinc finger BRCT_2 PF16589.5 KIK36642.1 - 2.4e-08 34.3 0.0 0.0086 16.5 0.0 2.2 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 KIK36642.1 - 1e-07 31.8 0.0 5.1e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 KIK36642.1 - 0.00014 22.2 0.0 0.0086 16.4 0.0 2.6 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Atg14 PF10186.9 KIK36644.1 - 0.012 14.8 0.2 0.013 14.6 0.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CHAT PF12770.7 KIK36645.1 - 3.7e-31 108.6 0.1 7.3e-31 107.7 0.1 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 KIK36645.1 - 1e-06 28.9 3.5 8.5 6.8 0.0 6.3 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_10 PF13374.6 KIK36645.1 - 6.7e-06 25.8 7.5 1.3 9.0 0.0 6.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK36645.1 - 0.0012 18.8 1.1 1.2e+02 3.2 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIK36645.1 - 0.0032 17.7 0.6 24 5.6 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Vta1_C PF18097.1 KIK36645.1 - 0.0033 17.1 1.9 0.95 9.2 0.1 3.0 2 0 0 2 2 2 2 Vta1 C-terminal domain TPR_1 PF00515.28 KIK36645.1 - 0.0068 16.2 0.5 31 4.6 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat C2 PF00168.30 KIK36645.1 - 0.099 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 C2 domain DEAD PF00270.29 KIK36646.1 - 0.017 14.9 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase WD40 PF00400.32 KIK36647.1 - 2e-17 63.2 6.5 4.7e-07 30.4 0.1 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36647.1 - 1.2e-06 28.7 0.1 0.00089 19.5 0.1 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK36647.1 - 0.017 13.8 0.0 0.37 9.4 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF952 PF06108.12 KIK36649.1 - 6.4e-22 77.4 0.0 8.3e-22 77.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) CorA PF01544.18 KIK36650.1 - 5.3e-12 45.7 13.5 8e-11 41.8 13.5 2.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein UBA_6 PF18039.1 KIK36652.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain CorA PF01544.18 KIK36653.1 - 2.4e-10 40.2 7.2 7.9e-10 38.5 7.2 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein LSR PF05624.14 KIK36656.1 - 0.39 10.7 5.9 0.64 10.1 5.9 1.4 1 1 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Peptidase_C54 PF03416.19 KIK36659.1 - 3.2e-104 348.2 0.0 4.1e-104 347.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Oxidored_FMN PF00724.20 KIK36660.1 - 1.6e-23 83.5 0.0 1.8e-23 83.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF4502 PF14950.6 KIK36662.1 - 0.16 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) DUF4718 PF15842.5 KIK36663.1 - 0.17 11.6 0.1 0.21 11.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) WD40 PF00400.32 KIK36664.1 - 6.8e-40 134.3 14.3 5.5e-07 30.2 0.0 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36664.1 - 7.6e-21 74.2 2.8 7.5e-05 23.0 0.1 5.7 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK36664.1 - 1.7e-07 30.3 3.1 0.13 10.9 0.1 4.9 2 1 1 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK36664.1 - 1.8e-06 27.2 0.0 0.38 9.7 0.0 4.8 3 2 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK36664.1 - 2.6e-06 27.4 0.2 0.0004 20.3 0.1 3.1 1 1 3 4 4 4 1 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.9 KIK36664.1 - 9.2e-05 22.3 0.2 0.016 15.0 0.1 2.8 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.16 KIK36664.1 - 0.013 14.1 0.1 0.28 9.6 0.1 2.5 1 1 1 3 3 3 0 Cytochrome D1 heme domain DUF4082 PF13313.6 KIK36664.1 - 0.67 10.0 2.7 1.9 8.5 0.1 2.7 2 1 2 4 4 4 0 Domain of unknown function (DUF4082) AAA PF00004.29 KIK36665.1 - 0.0035 17.7 0.0 0.0074 16.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KIK36665.1 - 0.012 15.7 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KIK36665.1 - 0.079 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 KIK36665.1 - 0.08 12.8 0.0 4.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF815 PF05673.13 KIK36665.1 - 0.082 12.1 0.0 0.18 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) B2 PF11473.8 KIK36665.1 - 0.094 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA binding protein B2 Oxidored_FMN PF00724.20 KIK36666.1 - 1.2e-92 310.9 0.0 1.4e-92 310.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.21 KIK36666.1 - 0.15 12.0 0.1 0.52 10.3 0.0 1.9 2 0 0 2 2 2 0 Tautomerase enzyme Methyltransf_11 PF08241.12 KIK36667.1 - 2.3e-22 79.4 0.0 3.9e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK36667.1 - 5.1e-20 72.0 0.0 8e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK36667.1 - 5.3e-12 45.8 0.0 8.3e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK36667.1 - 2.3e-11 44.3 0.0 3.6e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK36667.1 - 2e-09 37.2 0.0 2.8e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KIK36667.1 - 6.7e-08 32.5 0.0 9.9e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK36667.1 - 0.00072 19.1 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KIK36667.1 - 0.059 12.8 0.0 0.08 12.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 KIK36667.1 - 0.17 11.7 0.0 3.5 7.4 0.0 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase adh_short PF00106.25 KIK36668.1 - 6.8e-28 97.5 0.3 9.9e-25 87.1 0.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK36668.1 - 3e-16 59.7 0.4 6.3e-16 58.7 0.1 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK36668.1 - 3.3e-11 43.4 0.3 5.6e-11 42.7 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK36668.1 - 6.2e-06 25.8 0.0 7.9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK36668.1 - 0.0044 16.5 0.0 0.0053 16.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 KIK36668.1 - 0.026 14.6 0.1 0.095 12.8 0.1 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KIK36668.1 - 0.037 14.5 0.2 0.11 13.0 0.2 1.9 1 1 1 2 2 2 0 Putative NAD(P)-binding RmlD_sub_bind PF04321.17 KIK36668.1 - 0.084 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_transf_4 PF13439.6 KIK36668.1 - 0.14 12.2 0.0 0.71 9.9 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Suc_Fer-like PF06999.12 KIK36671.1 - 1.7e-27 96.5 0.0 1.9e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Lactonase PF10282.9 KIK36672.1 - 1.7e-36 126.2 0.0 2.1e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller AAA PF00004.29 KIK36673.1 - 0.0028 18.1 0.0 0.0044 17.4 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIK36673.1 - 0.013 15.5 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KIK36673.1 - 0.028 14.1 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 KIK36673.1 - 0.029 14.4 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KIK36673.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Glycos_transf_3 PF00591.21 KIK36676.1 - 3.5e-29 102.2 0.0 4.9e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KIK36676.1 - 0.0028 17.5 0.1 0.0044 16.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain SH3_6 PF12913.7 KIK36677.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 SH3 domain (SH3b1 type) DUF3987 PF13148.6 KIK36679.1 - 0.029 13.4 1.1 0.064 12.3 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DDE_1 PF03184.19 KIK36680.1 - 9.5e-06 25.4 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease AdoHcyase_NAD PF00670.21 KIK36682.1 - 7.5e-14 52.1 0.0 1.2e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF5417 PF17438.2 KIK36683.1 - 0.06 13.6 0.0 0.24 11.7 0.0 1.9 3 0 0 3 3 3 0 Family of unknown function (DUF5417) Citrate_synt PF00285.21 KIK36684.1 - 6.2e-12 45.3 0.0 1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain zf-C2H2 PF00096.26 KIK36688.1 - 8.8e-05 22.8 14.1 0.029 14.8 0.0 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK36688.1 - 0.0067 16.8 4.3 0.0067 16.8 4.3 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK36688.1 - 0.31 12.0 0.1 0.31 12.0 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 KIK36688.1 - 1.2 9.8 5.6 1.3 9.7 1.8 2.6 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 KIK36688.1 - 3.9 7.3 13.2 6.9 6.5 0.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain F-box-like PF12937.7 KIK36689.1 - 0.0013 18.6 1.8 0.064 13.2 0.0 3.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIK36689.1 - 0.0013 18.5 0.0 0.24 11.3 0.0 3.1 2 0 0 2 2 2 2 F-box domain VCBS PF13517.6 KIK36690.1 - 2.7e-28 98.3 21.8 1.1e-09 38.7 2.2 6.1 3 2 3 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KIK36690.1 - 6.9e-09 35.7 15.2 0.54 10.4 0.0 7.1 7 0 0 7 7 7 4 FG-GAP repeat TcdB_toxin_midN PF12256.8 KIK36690.1 - 0.076 12.4 9.1 36 3.7 0.1 6.3 3 1 4 7 7 7 0 Insecticide toxin TcdB middle/N-terminal region Itfg2 PF15907.5 KIK36690.1 - 0.17 10.9 0.0 0.39 9.7 0.0 1.6 1 0 0 1 1 1 0 Integrin-alpha FG-GAP repeat-containing protein 2 DUF1961 PF09224.11 KIK36690.1 - 0.18 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) BLACT_WH PF17778.1 KIK36691.1 - 4.7e-16 58.5 0.0 8.4e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 KIK36691.1 - 2.9e-14 53.5 5.5 5.2e-13 49.5 5.5 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIK36691.1 - 0.018 14.6 0.3 0.032 13.8 0.3 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Stork_head PF10264.9 KIK36691.1 - 0.16 12.2 0.0 0.59 10.3 0.0 1.9 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain MA3 PF02847.17 KIK36692.1 - 4.9e-26 90.9 0.1 1.1e-25 89.8 0.1 1.6 1 0 0 1 1 1 1 MA3 domain AF-4 PF05110.13 KIK36692.1 - 6.1e-07 28.0 14.7 6.1e-07 28.0 14.7 1.7 2 0 0 2 2 2 1 AF-4 proto-oncoprotein DUF1635 PF07795.11 KIK36692.1 - 7.8 6.3 8.8 4.9 6.9 3.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Peptidase_M50B PF13398.6 KIK36693.1 - 1.4e-56 191.3 18.5 1.9e-56 190.9 18.5 1.2 1 0 0 1 1 1 1 Peptidase M50B-like DUF3278 PF11683.8 KIK36693.1 - 0.21 11.7 1.6 0.23 11.5 0.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3278) ABC_tran PF00005.27 KIK36694.1 - 1.7e-42 145.2 0.1 1.5e-20 74.1 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIK36694.1 - 2.8e-17 63.5 0.1 0.0038 17.1 0.0 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIK36694.1 - 1.1e-12 47.9 1.1 0.0071 15.8 0.0 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIK36694.1 - 1.1e-07 31.4 0.1 0.018 14.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KIK36694.1 - 4.5e-07 30.6 1.5 0.013 16.0 0.0 2.9 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.17 KIK36694.1 - 8.3e-06 26.1 0.0 0.0036 17.4 0.0 2.8 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 KIK36694.1 - 2.6e-05 24.5 0.1 0.23 11.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KIK36694.1 - 4.1e-05 23.6 0.0 0.25 11.4 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK36694.1 - 6.3e-05 22.9 0.1 0.19 11.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KIK36694.1 - 8.5e-05 23.0 1.9 0.081 13.3 0.0 3.9 5 0 0 5 5 3 1 AAA ATPase domain RNA_helicase PF00910.22 KIK36694.1 - 0.00015 22.1 0.0 0.48 10.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA PF00004.29 KIK36694.1 - 0.00019 21.9 0.1 2.6 8.4 0.0 3.9 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KIK36694.1 - 0.00019 21.3 0.6 0.49 10.1 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain Chromo PF00385.24 KIK36694.1 - 0.00019 21.2 0.2 0.00047 20.0 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_18 PF13238.6 KIK36694.1 - 0.00021 21.8 0.0 0.5 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KIK36694.1 - 0.00029 21.1 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KIK36694.1 - 0.00042 20.5 0.1 1.6 8.9 0.1 3.1 3 1 0 3 3 2 2 AAA domain NACHT PF05729.12 KIK36694.1 - 0.00058 19.8 0.1 0.76 9.7 0.0 2.5 2 0 0 2 2 2 2 NACHT domain ATPase_2 PF01637.18 KIK36694.1 - 0.00062 19.7 0.5 2.8 7.8 0.0 3.5 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea MeaB PF03308.16 KIK36694.1 - 0.0013 17.7 0.2 0.29 10.1 0.1 2.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 KIK36694.1 - 0.0023 17.5 0.1 2.4 7.6 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region HEAT_2 PF13646.6 KIK36694.1 - 0.0034 17.7 14.4 0.022 15.1 0.3 3.4 2 1 0 2 2 2 1 HEAT repeats 4HB PF17947.1 KIK36694.1 - 0.0061 16.6 0.0 0.02 14.9 0.0 1.9 1 0 0 1 1 1 1 Four helical bundle domain AAA_24 PF13479.6 KIK36694.1 - 0.0085 15.8 0.8 2.6 7.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.6 KIK36694.1 - 0.0098 16.1 0.1 1.8 8.8 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF815 PF05673.13 KIK36694.1 - 0.016 14.4 0.4 2.8 7.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 KIK36694.1 - 0.021 14.5 1.7 4.6 6.9 0.1 3.3 4 0 0 4 4 2 0 AAA domain Roc PF08477.13 KIK36694.1 - 0.027 14.7 0.0 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_13 PF13166.6 KIK36694.1 - 0.03 13.0 0.7 2.2 6.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KIK36694.1 - 0.045 12.9 0.1 6.6 5.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain CLP1_P PF16575.5 KIK36694.1 - 0.047 13.5 0.9 12 5.7 0.0 3.2 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TsaE PF02367.17 KIK36694.1 - 0.074 13.1 0.0 17 5.4 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 KIK36694.1 - 0.076 13.1 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 Dynamin family NTPase_1 PF03266.15 KIK36694.1 - 0.086 12.8 0.1 11 5.9 0.0 2.9 2 0 0 2 2 2 0 NTPase DUF3437 PF11919.8 KIK36694.1 - 0.092 12.7 1.2 2.1 8.3 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) U3snoRNP10 PF12397.8 KIK36694.1 - 0.12 12.7 0.8 0.34 11.3 0.8 1.8 1 1 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 AAA_27 PF13514.6 KIK36694.1 - 0.13 11.9 0.1 11 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KIK36694.1 - 0.17 11.5 1.8 15 5.2 0.1 3.5 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 KIK36694.1 - 0.71 9.9 3.7 18 5.3 0.1 3.8 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) V_ATPase_I PF01496.19 KIK36695.1 - 0 1065.1 0.0 0 1065.0 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family zf-C2H2_4 PF13894.6 KIK36696.1 - 0.021 15.6 6.5 0.4 11.7 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KIK36696.1 - 0.27 11.6 5.6 0.36 11.2 2.0 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Lsm_interact PF05391.11 KIK36696.1 - 0.34 10.5 1.7 6.2 6.5 0.4 2.9 2 0 0 2 2 2 0 Lsm interaction motif SGL PF08450.12 KIK36697.1 - 1.3e-24 87.2 0.0 2.1e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KIK36697.1 - 2.5e-06 27.5 0.0 1.7e-05 24.9 0.0 2.3 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 KIK36697.1 - 4.5e-05 23.6 0.0 0.00013 22.1 0.0 1.7 1 0 0 1 1 1 1 Arylesterase NHL PF01436.21 KIK36697.1 - 0.0048 16.9 0.1 0.026 14.6 0.0 2.4 2 0 0 2 2 2 1 NHL repeat SGL PF08450.12 KIK36698.1 - 3.4e-22 79.2 0.0 5.3e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KIK36698.1 - 2.2e-05 24.5 0.0 7.3e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 KIK36698.1 - 0.00022 21.4 0.1 0.0012 19.0 0.0 2.3 3 0 0 3 3 3 1 Arylesterase SGL PF08450.12 KIK36700.1 - 1.8e-20 73.6 0.0 2.6e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KIK36700.1 - 1.4e-06 28.4 0.0 5.4e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 KIK36700.1 - 4.2e-05 23.7 0.0 0.00016 21.8 0.0 2.0 2 0 0 2 2 2 1 Arylesterase PD40 PF07676.12 KIK36700.1 - 0.026 14.5 1.5 0.62 10.1 0.1 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Kelch_3 PF13415.6 KIK36700.1 - 0.091 13.1 0.0 29 5.1 0.1 2.8 2 0 0 2 2 2 0 Galactose oxidase, central domain FA_desaturase PF00487.24 KIK36701.1 - 2.4e-16 60.4 22.8 4.6e-16 59.4 22.8 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KIK36701.1 - 4.1e-10 39.6 0.0 9.1e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TPR_2 PF07719.17 KIK36702.1 - 9.5e-07 28.5 6.3 0.061 13.5 0.4 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK36702.1 - 0.00059 19.5 6.3 0.00063 19.4 0.3 3.0 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.28 KIK36702.1 - 0.072 12.9 7.0 1.8 8.6 0.5 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat VIT_2 PF13757.6 KIK36702.1 - 0.13 12.2 0.1 0.48 10.4 0.1 1.8 1 1 1 2 2 2 0 Vault protein inter-alpha-trypsin domain TPR_16 PF13432.6 KIK36702.1 - 2.4 8.9 6.6 43 4.9 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat DDE_3 PF13358.6 KIK36704.1 - 1.6e-07 31.2 0.0 1.7e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 KIK36705.1 - 0.00016 21.3 0.1 0.001 18.7 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KIK36705.1 - 0.00037 20.7 0.4 0.0013 18.9 0.1 2.0 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 KIK36705.1 - 0.0017 18.1 0.3 0.03 14.1 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KIK36705.1 - 0.0022 18.0 0.5 0.0049 16.9 0.1 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.6 KIK36705.1 - 0.0066 16.2 0.0 0.098 12.4 0.0 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.6 KIK36705.1 - 0.0084 16.7 0.0 0.052 14.2 0.0 2.1 1 1 1 2 2 2 1 Homeodomain-like domain DDE_1 PF03184.19 KIK36709.1 - 1.7e-06 27.8 0.0 1.9e-06 27.7 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 KIK36710.1 - 8.7e-11 41.8 0.0 9.8e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF659 PF04937.15 KIK36711.1 - 4.1e-17 62.4 2.5 9e-17 61.3 2.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) FR47 PF08445.10 KIK36712.1 - 0.011 15.7 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_1 PF00583.25 KIK36712.1 - 0.011 16.0 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK36712.1 - 0.018 15.5 0.0 0.032 14.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Dimer_Tnp_hAT PF05699.14 KIK36713.1 - 0.021 14.6 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region PRP3 PF08572.10 KIK36714.1 - 1.1e-72 244.4 7.5 1.1e-72 244.4 7.5 1.7 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KIK36714.1 - 1.9e-42 144.8 0.0 1.9e-42 144.8 0.0 2.6 4 0 0 4 4 4 1 Protein of unknown function (DUF1115) GramPos_pilinD1 PF16555.5 KIK36714.1 - 1.8 8.7 7.5 0.27 11.4 0.7 2.8 4 0 0 4 4 4 0 Gram-positive pilin subunit D1, N-terminal domain BTB PF00651.31 KIK36715.1 - 2.4e-09 37.4 0.0 1e-08 35.4 0.0 2.0 3 0 0 3 3 3 1 BTB/POZ domain CAP_GLY PF01302.25 KIK36715.1 - 1.2e-07 31.6 0.6 3.5e-06 27.0 0.4 2.5 2 0 0 2 2 2 1 CAP-Gly domain Sel1 PF08238.12 KIK36716.1 - 6e-20 71.2 16.4 3.2e-06 27.6 0.2 7.2 7 0 0 7 7 7 5 Sel1 repeat tRNA-synt_1c PF00749.21 KIK36716.1 - 0.062 12.2 0.2 0.093 11.6 0.2 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain SpoIIE PF07228.12 KIK36717.1 - 0.0016 18.4 0.0 0.0039 17.1 0.0 1.6 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KIK36717.1 - 0.0027 17.4 0.0 1.7 8.2 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KIK36717.1 - 0.042 13.5 0.2 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein phosphatase 2C OprD PF03573.13 KIK36717.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 outer membrane porin, OprD family Epimerase PF01370.21 KIK36718.1 - 1.1e-37 129.8 0.0 1.6e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK36718.1 - 1.7e-24 86.9 0.0 2.6e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Glycos_transf_2 PF00535.26 KIK36718.1 - 1.1e-14 54.6 0.6 3e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 3Beta_HSD PF01073.19 KIK36718.1 - 1.8e-13 50.1 0.0 3.5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KIK36718.1 - 1.2e-07 31.8 0.0 1.9e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Glyco_tranf_2_3 PF13641.6 KIK36718.1 - 8.6e-07 29.1 0.0 4e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 NAD_binding_4 PF07993.12 KIK36718.1 - 2.2e-05 23.8 0.0 0.011 14.9 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KIK36718.1 - 3e-05 23.3 0.0 4.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KIK36718.1 - 4.1e-05 22.8 0.0 0.0024 17.1 0.0 2.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KIK36718.1 - 0.00015 21.4 0.0 0.0003 20.4 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Glyco_tranf_2_2 PF10111.9 KIK36718.1 - 0.00064 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_5 PF13712.6 KIK36718.1 - 0.042 13.5 0.0 8.5 6.0 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase like family Glyco_transf_8 PF01501.20 KIK36719.1 - 4.3e-25 88.7 0.0 1.2e-24 87.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_24 PF13578.6 KIK36719.1 - 7.8e-19 68.7 0.1 4.1e-18 66.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Glyco_transf_24 PF18404.1 KIK36719.1 - 1.9e-05 24.3 0.0 4.7e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Glucosyltransferase 24 BPS1 PF05633.11 KIK36720.1 - 0.058 12.4 0.3 0.054 12.5 0.3 1.0 1 0 0 1 1 1 0 Protein BYPASS1-related MRF_C1 PF13887.6 KIK36725.1 - 0.097 11.8 0.6 0.19 10.9 0.6 1.5 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 Cpn60_TCP1 PF00118.24 KIK36727.1 - 1.9e-148 495.2 0.6 2.1e-148 495.0 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EAL PF00563.20 KIK36727.1 - 0.12 11.9 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 EAL domain RhoGAP PF00620.27 KIK36728.1 - 2.1e-42 144.5 0.0 5.9e-42 143.1 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.19 KIK36728.1 - 6.8e-12 45.9 0.0 5.8e-08 33.1 0.0 2.9 2 0 0 2 2 2 2 RasGEF domain PH_9 PF15410.6 KIK36728.1 - 8.1e-08 32.7 0.1 2.9e-06 27.7 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KIK36728.1 - 3.9e-07 30.5 0.1 0.0001 22.8 0.0 2.5 2 0 0 2 2 2 2 PH domain RasGEF_N PF00618.20 KIK36728.1 - 1.1e-05 25.6 0.0 0.0001 22.5 0.0 2.8 2 1 0 2 2 2 1 RasGEF N-terminal motif GST_N_3 PF13417.6 KIK36730.1 - 3e-17 62.8 0.0 5.7e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK36730.1 - 2.4e-16 59.8 0.0 4.4e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK36730.1 - 3.3e-11 43.3 0.0 4.7e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KIK36730.1 - 4.5e-09 36.5 0.0 8.1e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIK36730.1 - 1.9e-05 24.8 0.0 3.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK36730.1 - 0.00024 21.1 0.1 0.00041 20.3 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KIK36730.1 - 0.014 16.1 0.0 0.028 15.1 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_N_3 PF13417.6 KIK36731.1 - 7.7e-17 61.5 0.0 1.5e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK36731.1 - 6.4e-16 58.5 0.0 1.2e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK36731.1 - 5.1e-12 45.9 0.0 8.8e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KIK36731.1 - 1.3e-10 41.4 0.0 2.6e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIK36731.1 - 1.6e-05 25.0 0.0 3.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK36731.1 - 2.8e-05 24.1 0.1 4.7e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KIK36731.1 - 0.042 14.6 0.0 0.11 13.3 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KIK36731.1 - 0.096 12.5 0.0 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Methyltransf_19 PF04672.12 KIK36731.1 - 0.23 10.9 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl methyltransferase DHHA2 PF02833.14 KIK36733.1 - 1.1e-15 58.0 0.0 2.1e-14 53.9 0.0 2.2 1 1 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KIK36733.1 - 1.2e-09 38.2 0.0 2.6e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 DHH family CHASE3 PF05227.13 KIK36734.1 - 0.054 13.4 0.0 0.057 13.3 0.0 1.0 1 0 0 1 1 1 0 CHASE3 domain DUF3421 PF11901.8 KIK36735.1 - 1e-33 115.7 0.2 1.9e-32 111.6 0.0 1.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) eIF3_N PF09440.10 KIK36736.1 - 8e-46 155.8 2.8 1.8e-45 154.7 2.8 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KIK36736.1 - 2.9e-08 34.1 0.1 1.3e-07 32.1 0.0 2.1 2 0 0 2 2 2 1 PCI domain PQ-loop PF04193.14 KIK36737.1 - 4.6e-23 80.8 3.3 3.5e-11 42.7 0.4 2.7 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 KIK36737.1 - 0.18 12.7 3.5 0.32 11.8 3.5 1.4 1 0 0 1 1 1 0 ER lumen protein retaining receptor F-box-like PF12937.7 KIK36738.1 - 3.2e-06 26.9 0.0 9.6e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like CD99L2 PF12301.8 KIK36739.1 - 0.00013 22.3 0.4 0.00026 21.3 0.3 1.5 1 1 0 1 1 1 1 CD99 antigen like protein 2 CE2_N PF17996.1 KIK36739.1 - 0.0081 16.1 0.3 1.6 8.8 0.2 2.5 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal DUF4690 PF15756.5 KIK36739.1 - 0.074 13.7 0.4 0.26 11.9 0.4 1.9 1 0 0 1 1 1 0 Small Novel Rich in Cartilage KDZ PF18758.1 KIK36740.1 - 8e-63 212.0 0.0 1.7e-62 211.0 0.0 1.6 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK36740.1 - 3.7e-44 149.3 0.2 9e-44 148.0 0.2 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK36740.1 - 0.00049 20.2 0.1 0.0015 18.6 0.1 1.8 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK36740.1 - 0.032 14.1 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases CEBP_ZZ PF16366.5 KIK36740.1 - 0.33 11.2 4.3 0.93 9.8 4.3 1.7 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain CDRT4 PF15213.6 KIK36742.1 - 0.64 10.6 3.7 0.36 11.4 0.2 2.3 2 0 0 2 2 2 0 CMT1A duplicated region transcript 4 protein Plavaka PF18759.1 KIK36743.1 - 2.9e-35 122.0 0.0 4.8e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase DUF4423 PF14394.6 KIK36743.1 - 0.1 12.3 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) CLZ PF16526.5 KIK36744.1 - 0.04 14.3 5.4 0.097 13.0 4.3 2.3 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_1 PF00170.21 KIK36744.1 - 0.069 13.3 5.7 1.9 8.6 0.5 3.7 2 1 1 3 3 3 0 bZIP transcription factor TSC22 PF01166.18 KIK36744.1 - 0.34 11.2 2.9 24 5.3 0.0 3.4 2 1 1 3 3 3 0 TSC-22/dip/bun family Tropomyosin_1 PF12718.7 KIK36744.1 - 0.36 11.0 7.0 0.17 12.0 2.8 2.3 2 0 0 2 2 2 0 Tropomyosin like CENP-Q PF13094.6 KIK36744.1 - 1.3 9.2 9.8 0.59 10.3 1.0 2.9 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit ABC_tran PF00005.27 KIK36745.1 - 7.9e-14 52.3 0.0 0.00086 19.8 0.0 3.9 2 1 1 3 3 3 3 ABC transporter Integrase_H2C2 PF17921.1 KIK36745.1 - 4e-05 23.7 0.3 0.0023 18.0 0.1 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain AAA_21 PF13304.6 KIK36745.1 - 0.011 15.5 0.3 0.68 9.7 0.0 2.4 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIK36745.1 - 0.025 15.1 0.0 0.05 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 KIK36745.1 - 0.12 11.4 11.3 0.23 10.5 11.3 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF668 PF05003.12 KIK36745.1 - 0.15 12.5 0.0 0.38 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF668) TspO_MBR PF03073.15 KIK36745.1 - 0.23 11.5 8.4 0.5 10.4 8.4 1.5 1 0 0 1 1 1 0 TspO/MBR family Baculo_PEP_C PF04513.12 KIK36749.1 - 0.016 15.3 1.1 0.016 15.3 1.1 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF148 PF02520.17 KIK36749.1 - 0.043 13.9 0.6 0.13 12.4 0.5 1.9 1 1 0 1 1 1 0 Domain of unknown function DUF148 DUF1664 PF07889.12 KIK36749.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Miga PF10265.9 KIK36749.1 - 5.4 5.9 8.3 22 3.8 6.2 2.0 2 0 0 2 2 2 0 Mitoguardin MMR_HSR1 PF01926.23 KIK36751.1 - 7.4e-06 26.0 0.0 3.9e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK36751.1 - 2.9e-05 24.1 0.1 0.0017 18.3 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase G-alpha PF00503.20 KIK36751.1 - 0.0031 16.7 1.9 1.8 7.6 0.1 3.2 2 1 0 3 3 3 2 G-protein alpha subunit AAA_24 PF13479.6 KIK36751.1 - 0.0039 16.9 0.0 0.47 10.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KIK36751.1 - 0.0067 16.9 0.0 0.045 14.3 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 KIK36751.1 - 0.018 14.8 0.0 0.07 12.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Septin PF00735.18 KIK36751.1 - 0.035 13.4 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 KIK36751.1 - 0.036 14.4 0.7 0.15 12.4 0.1 2.2 2 1 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 KIK36751.1 - 0.091 13.0 0.0 0.45 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain DREPP PF05558.12 KIK36751.1 - 0.17 11.7 0.6 1.8 8.4 0.1 2.2 2 0 0 2 2 2 0 DREPP plasma membrane polypeptide AAA_18 PF13238.6 KIK36751.1 - 0.25 11.9 0.8 3.9 8.0 0.4 2.6 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KIK36751.1 - 2.2 8.0 5.5 14 5.4 0.1 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Dicer_N PF17895.1 KIK36752.1 - 0.15 11.9 0.2 0.15 11.9 0.2 1.1 1 0 0 1 1 1 0 Giardia Dicer N-terminal domain MMR_HSR1 PF01926.23 KIK36753.1 - 0.013 15.6 0.0 0.027 14.6 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase MMR_HSR1 PF01926.23 KIK36754.1 - 9.8e-05 22.4 0.1 0.0002 21.4 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 KIK36754.1 - 0.0007 19.1 0.0 0.0018 17.8 0.0 1.6 2 0 0 2 2 2 1 Bacterial TniB protein Arf PF00025.21 KIK36754.1 - 0.00093 18.7 0.0 0.0032 16.9 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KIK36754.1 - 0.0054 17.0 0.0 0.018 15.2 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KIK36754.1 - 0.011 15.6 0.0 0.94 9.4 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 KIK36754.1 - 0.048 12.8 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_14 PF13173.6 KIK36754.1 - 0.061 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIK36754.1 - 0.094 12.6 1.1 0.47 10.3 0.2 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK36754.1 - 0.098 12.9 0.1 1.6 9.0 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KIK36754.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIK36754.1 - 0.18 12.3 0.0 0.34 11.4 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Tudor_1_RapA PF18339.1 KIK36755.1 - 0.0064 16.4 0.1 0.45 10.5 0.0 2.2 2 0 0 2 2 2 2 RapA N-terminal Tudor like domain 1 Pkinase PF00069.25 KIK36758.1 - 6.5e-14 51.9 0.0 8.4e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK36758.1 - 1.1e-12 47.9 0.0 1.3e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.17 KIK36759.1 - 5.6e-10 38.9 0.0 7.2e-10 38.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK36759.1 - 0.0005 19.5 0.0 0.00057 19.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain GLTP PF08718.11 KIK36760.1 - 1.4e-29 103.3 0.0 2.1e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Glyco_hydro_3_C PF01915.22 KIK36762.1 - 8.1e-64 215.3 0.0 1.2e-63 214.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KIK36762.1 - 2.1e-21 75.8 0.2 5.6e-21 74.4 0.2 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 KIK36762.1 - 7.5e-16 58.4 0.0 2.3e-15 56.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Cyto_heme_lyase PF01265.17 KIK36764.1 - 2e-47 162.2 2.5 2.2e-46 158.8 2.5 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase XRN1_DBM PF18245.1 KIK36764.1 - 0.12 12.4 1.9 0.42 10.6 1.9 2.0 1 0 0 1 1 1 0 5-3 exonuclease XRN1 DCP1-binding motif Asp_protease_2 PF13650.6 KIK36766.1 - 0.0002 22.0 0.0 0.00067 20.3 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK36766.1 - 0.002 18.6 0.0 0.0063 17.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease WD40 PF00400.32 KIK36767.1 - 0.00015 22.4 12.4 1.3 10.0 0.4 6.1 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36767.1 - 0.00018 21.8 0.0 0.026 14.8 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK36767.1 - 0.00023 20.2 0.1 0.31 9.9 0.0 2.3 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein GCFC PF07842.12 KIK36768.1 - 4.1e-78 262.8 3.8 6.5e-78 262.1 3.8 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 KIK36768.1 - 4.8e-13 49.4 12.4 4.8e-13 49.4 12.4 2.9 3 1 0 3 3 3 1 Tuftelin interacting protein N terminal G-patch PF01585.23 KIK36768.1 - 1e-11 44.5 2.7 3.7e-11 42.7 2.7 2.0 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KIK36768.1 - 1.3e-05 25.2 0.4 1.3e-05 25.2 0.4 3.4 4 0 0 4 4 4 1 G-patch domain DUF4196 PF13846.6 KIK36769.1 - 0.082 13.1 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) Plavaka PF18759.1 KIK36771.1 - 9.5e-37 126.9 0.0 1.6e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase SDA1 PF05285.12 KIK36771.1 - 0.032 13.7 7.3 0.048 13.1 7.3 1.2 1 0 0 1 1 1 0 SDA1 CHAT PF12770.7 KIK36772.1 - 6.1e-44 150.6 0.0 1.2e-43 149.6 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK36772.1 - 7.6e-09 35.2 2.8 0.00037 20.3 0.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK36772.1 - 0.006 16.9 7.1 0.12 12.6 2.1 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK36772.1 - 0.019 15.0 3.4 11 6.4 0.3 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK36772.1 - 0.028 14.2 0.8 13 5.9 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4471 PF14740.6 KIK36772.1 - 0.21 10.8 0.0 4.8 6.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) TPR_14 PF13428.6 KIK36772.1 - 5.5 8.1 9.3 27 5.9 0.6 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.32 KIK36773.1 - 0.0008 20.2 1.2 0.013 16.4 0.9 2.6 2 1 0 2 2 2 1 WD domain, G-beta repeat DUF4259 PF14078.6 KIK36774.1 - 0.017 15.9 1.9 0.032 15.0 0.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4259) ATG16 PF08614.11 KIK36774.1 - 0.031 14.5 12.7 0.82 9.9 0.1 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) WSD PF15613.6 KIK36774.1 - 0.25 11.8 1.6 28 5.3 0.0 2.3 2 1 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Fez1 PF06818.15 KIK36774.1 - 0.32 11.4 13.9 1.9 8.9 14.0 1.9 1 1 0 1 1 1 0 Fez1 CENP-F_leu_zip PF10473.9 KIK36774.1 - 2.5 8.1 20.6 4.8 7.2 3.3 3.1 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 KIK36774.1 - 3.4 8.1 10.0 0.22 11.9 1.7 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Pkinase PF00069.25 KIK36775.1 - 7.8e-72 241.8 0.0 1e-71 241.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK36775.1 - 9.2e-40 136.6 0.0 1.3e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KIK36775.1 - 1.7e-18 67.1 1.1 1.4e-13 51.3 0.6 3.5 1 1 1 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KIK36775.1 - 2.2e-13 50.1 0.6 4.6e-13 49.0 0.3 1.7 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KIK36775.1 - 5.1e-06 26.0 0.0 8.1e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KIK36775.1 - 0.0014 18.3 0.1 0.0023 17.5 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KIK36775.1 - 0.0022 17.0 0.0 0.0034 16.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIK36775.1 - 0.0091 15.9 0.3 0.18 11.7 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KIK36775.1 - 0.099 12.0 0.2 0.6 9.4 0.2 2.0 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2235 PF09994.9 KIK36776.1 - 1.2e-90 303.7 0.0 1.5e-90 303.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Fungal_trans PF04082.18 KIK36777.1 - 1.1e-16 60.7 0.5 1.9e-16 59.9 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK36777.1 - 0.00017 21.6 13.0 0.00031 20.8 13.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2214 PF09980.9 KIK36778.1 - 0.074 12.9 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2214) Pkinase PF00069.25 KIK36781.1 - 6.4e-40 137.2 0.0 7.9e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK36781.1 - 2.9e-22 79.2 0.0 3.7e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIK36781.1 - 1.1e-06 28.2 0.1 1.7e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK36781.1 - 3.9e-06 25.9 0.0 7.7e-06 24.9 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KIK36781.1 - 0.0003 20.2 0.0 0.00046 19.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIK36781.1 - 0.0044 17.0 0.0 0.014 15.3 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK36781.1 - 0.13 11.2 0.0 0.16 10.9 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 KIK36783.1 - 8.9e-08 31.8 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain NIF PF03031.18 KIK36785.1 - 9.9e-55 184.6 0.6 1.9e-54 183.6 0.2 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase HAD PF12710.7 KIK36785.1 - 0.033 14.6 0.1 0.18 12.2 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase DUF1387 PF07139.11 KIK36785.1 - 2.4 7.8 16.3 4.2 7.0 16.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) ASD2 PF08687.11 KIK36785.1 - 4.6 6.7 5.7 7.2 6.1 5.7 1.5 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 UBA PF00627.31 KIK36786.1 - 1e-26 92.4 5.9 3.3e-15 55.6 0.3 2.9 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 KIK36786.1 - 4.6e-21 74.3 1.9 7.4e-21 73.7 1.9 1.3 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 KIK36786.1 - 1.2e-20 72.9 12.2 1.2e-20 72.9 12.2 2.0 2 0 0 2 2 1 1 XPC-binding domain Rad60-SLD PF11976.8 KIK36786.1 - 1.4e-08 34.4 1.6 2.4e-08 33.7 1.6 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 KIK36786.1 - 0.00049 19.8 0.0 0.017 14.9 0.0 2.4 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.6 KIK36786.1 - 0.00067 19.7 0.0 0.0017 18.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KIK36786.1 - 0.031 14.6 1.1 0.052 13.9 1.1 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 KIK36786.1 - 0.031 14.8 0.0 0.066 13.8 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.6 KIK36786.1 - 0.037 14.5 0.4 0.097 13.1 0.4 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain ResB PF05140.14 KIK36786.1 - 0.089 11.5 0.3 0.092 11.5 0.3 1.2 1 0 0 1 1 1 0 ResB-like family Ubiquitin_4 PF18036.1 KIK36786.1 - 0.25 11.4 0.6 2.1 8.4 0.1 2.2 1 1 1 2 2 2 0 Ubiquitin-like domain MSP1a PF11670.8 KIK36786.1 - 0.34 10.1 0.0 0.34 10.1 0.0 2.5 2 1 0 3 3 3 0 Major surface protein 1a (MSP1a) FlgN PF05130.12 KIK36786.1 - 2.2 8.8 5.9 0.86 10.1 0.8 2.6 3 0 0 3 3 3 0 FlgN protein DUF3135 PF11333.8 KIK36786.1 - 2.5 8.4 7.1 0.83 9.9 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3135) Pex14_N PF04695.13 KIK36786.1 - 4.9 7.8 14.9 4.5 7.9 3.2 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LRR_4 PF12799.7 KIK36787.1 - 7.9e-12 45.2 14.6 4.2e-05 23.8 0.9 5.0 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIK36787.1 - 5.9e-11 42.0 15.0 5e-08 32.6 7.4 3.9 4 0 0 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 KIK36787.1 - 9.5e-05 22.0 0.8 0.00067 19.2 0.4 2.1 1 1 1 2 2 2 2 Leucine-rich repeat Arf PF00025.21 KIK36788.1 - 1.4e-76 255.8 0.0 1.6e-76 255.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KIK36788.1 - 3.7e-15 56.2 0.1 5.1e-15 55.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KIK36788.1 - 8e-13 48.3 0.0 8.3e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KIK36788.1 - 1.3e-11 44.3 1.3 2.8e-07 30.1 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KIK36788.1 - 1.4e-11 44.2 0.0 1.7e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KIK36788.1 - 2.9e-09 36.6 0.0 3.6e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIK36788.1 - 0.00011 22.2 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KIK36788.1 - 0.018 14.4 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase PALP PF00291.25 KIK36789.1 - 4.9e-71 239.5 0.1 5.7e-71 239.3 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Frataxin_Cyay PF01491.16 KIK36789.1 - 0.032 14.3 0.4 0.61 10.2 0.1 2.7 2 1 0 2 2 2 0 Frataxin-like domain zf-U1 PF06220.12 KIK36790.1 - 1e-08 34.8 5.2 1.6e-08 34.2 5.2 1.3 1 0 0 1 1 1 1 U1 zinc finger Chitin_synth_1 PF01644.17 KIK36791.1 - 2.3e-74 248.8 0.0 3.8e-74 248.1 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KIK36791.1 - 1.5e-26 92.1 0.1 3.4e-26 91.0 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KIK36791.1 - 3.6e-24 85.3 6.1 5.1e-17 61.7 0.1 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KIK36791.1 - 0.00015 21.8 0.1 0.00015 21.8 0.1 2.9 2 2 0 2 2 2 1 Glycosyl transferase family group 2 DUF1029 PF06269.12 KIK36792.1 - 0.13 12.4 0.4 0.22 11.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1029) F-box-like PF12937.7 KIK36793.1 - 0.0031 17.4 0.0 0.022 14.7 0.0 2.5 2 0 0 2 2 2 1 F-box-like TPP1 PF10341.9 KIK36795.1 - 8.9e-09 35.3 0.0 1.2e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD Cyto_heme_lyase PF01265.17 KIK36799.1 - 4.5e-48 164.3 2.2 3.2e-47 161.5 2.2 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase WD40 PF00400.32 KIK36803.1 - 1e-28 99.0 9.0 0.00017 22.3 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36803.1 - 6.2e-15 55.3 0.1 0.00026 21.2 0.0 5.8 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK36803.1 - 1.5e-07 31.5 0.0 0.0034 17.3 0.0 3.4 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK36803.1 - 7.3e-05 21.9 0.1 0.016 14.2 0.1 3.6 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK36803.1 - 0.00047 20.0 0.1 8.6 6.4 0.0 5.0 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK36803.1 - 0.0077 15.6 0.0 0.77 9.0 0.0 3.2 4 1 1 5 5 5 1 WD40-like domain PALB2_WD40 PF16756.5 KIK36803.1 - 0.015 14.2 0.1 1.3 7.8 0.0 2.4 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain DUF1513 PF07433.11 KIK36803.1 - 0.025 13.7 0.0 0.43 9.6 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) Hira PF07569.11 KIK36803.1 - 0.048 13.4 0.2 2.3 7.9 0.0 2.9 3 0 0 3 3 3 0 TUP1-like enhancer of split Gmad1 PF10647.9 KIK36803.1 - 0.14 11.9 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain F-box-like PF12937.7 KIK36804.1 - 6.2e-07 29.2 3.8 6.2e-07 29.2 3.8 2.2 1 1 1 2 2 2 1 F-box-like F-box PF00646.33 KIK36804.1 - 1.1 9.2 6.2 0.88 9.5 0.1 3.1 3 0 0 3 3 3 0 F-box domain Lactonase PF10282.9 KIK36806.1 - 1.7e-43 149.2 0.0 2.1e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller WD40 PF00400.32 KIK36807.1 - 2e-43 145.5 9.8 4e-07 30.6 0.0 8.1 7 1 1 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36807.1 - 1.5e-13 50.8 0.0 0.076 13.3 0.0 5.9 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 KIK36807.1 - 1.5e-09 38.4 2.6 1.1e-08 35.5 0.2 2.5 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Ge1_WD40 PF16529.5 KIK36807.1 - 3.9e-05 22.8 0.0 0.015 14.3 0.0 2.9 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CPSF_A PF03178.15 KIK36807.1 - 0.0044 16.4 0.0 0.021 14.1 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region eIF2A PF08662.11 KIK36807.1 - 0.0067 16.3 0.0 7 6.5 0.0 3.2 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK36807.1 - 0.017 15.1 0.0 36 4.4 0.0 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK36807.1 - 0.045 13.1 0.3 4.2 6.6 0.0 3.2 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal MMR_HSR1 PF01926.23 KIK36808.1 - 0.0004 20.4 0.0 0.00048 20.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KIK36808.1 - 0.00078 19.7 0.0 0.001 19.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK36808.1 - 0.00086 18.8 0.0 0.001 18.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family TniB PF05621.11 KIK36808.1 - 0.0019 17.7 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial TniB protein ATP-synt_ab PF00006.25 KIK36808.1 - 0.0048 16.6 0.1 0.0062 16.2 0.1 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain G-alpha PF00503.20 KIK36808.1 - 0.034 13.3 0.0 0.036 13.2 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit FeoB_N PF02421.18 KIK36808.1 - 0.036 13.6 0.0 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 KIK36808.1 - 0.043 13.6 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Parvo_NS1 PF01057.17 KIK36808.1 - 0.048 12.8 0.0 0.051 12.7 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SRPRB PF09439.10 KIK36808.1 - 0.06 12.8 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KIK36808.1 - 0.061 13.6 0.0 0.082 13.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 KIK36808.1 - 0.064 13.2 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MCM PF00493.23 KIK36808.1 - 0.072 12.2 0.0 0.072 12.2 0.0 1.1 1 0 0 1 1 1 0 MCM P-loop domain ATPase_2 PF01637.18 KIK36808.1 - 0.092 12.6 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KIK36808.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 KIK36808.1 - 0.13 11.5 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Septin NB-ARC PF00931.22 KIK36808.1 - 0.13 11.4 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain DUF485 PF04341.12 KIK36809.1 - 0.18 11.7 2.4 1.6 8.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Arteri_nsp7a PF16749.5 KIK36812.1 - 0.0036 17.5 0.2 0.0043 17.2 0.2 1.2 1 0 0 1 1 1 1 Arterivirus nonstructural protein 7 alpha Aldo_ket_red PF00248.21 KIK36814.1 - 3.3e-39 134.8 0.0 3.6e-33 115.0 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Aldo_ket_red PF00248.21 KIK36815.1 - 1.7e-45 155.5 0.0 9.5e-38 130.1 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Aldo_ket_red PF00248.21 KIK36816.1 - 2.9e-46 158.0 0.0 1.5e-38 132.7 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family F-box-like PF12937.7 KIK36817.1 - 0.017 15.0 0.1 0.082 12.8 0.1 2.3 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KIK36817.1 - 0.087 12.7 0.8 0.33 10.9 0.0 2.5 3 0 0 3 3 3 0 F-box domain Nup84_Nup100 PF04121.13 KIK36818.1 - 4.8e-168 560.6 0.0 5.5e-168 560.4 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Nic96 PF04097.14 KIK36818.1 - 0.0098 14.4 0.0 0.019 13.5 0.0 1.4 1 0 0 1 1 1 1 Nup93/Nic96 PPR_1 PF12854.7 KIK36818.1 - 0.033 13.9 0.1 1.1 9.0 0.1 2.7 2 0 0 2 2 2 0 PPR repeat TPR_14 PF13428.6 KIK36818.1 - 0.44 11.5 4.8 0.67 10.9 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat CHAT PF12770.7 KIK36819.1 - 3.1e-20 72.8 0.0 3.5e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 CHAT domain Surp PF01805.20 KIK36819.1 - 0.013 15.5 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Surp module DUF2987 PF11205.8 KIK36820.1 - 0.0052 16.7 0.0 0.0088 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2987) TPR_12 PF13424.6 KIK36821.1 - 3.1e-13 49.8 7.9 0.019 15.2 0.0 7.4 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_10 PF13374.6 KIK36821.1 - 1e-10 41.1 15.1 0.00061 19.6 0.0 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIK36821.1 - 1e-07 32.5 1.3 0.084 13.5 0.0 5.8 3 2 4 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK36821.1 - 8.2e-05 22.4 7.2 24 5.3 0.0 7.8 10 1 0 10 10 10 0 Tetratricopeptide repeat PsbL PF02419.17 KIK36821.1 - 0.00038 20.4 15.6 35 4.5 0.0 7.4 8 0 0 8 8 8 0 PsbL protein TPR_1 PF00515.28 KIK36821.1 - 0.031 14.1 9.5 20 5.2 0.0 8.4 12 0 0 12 12 12 0 Tetratricopeptide repeat E1-N PF14463.6 KIK36821.1 - 0.091 12.6 0.1 2.7e+02 1.3 0.0 4.9 2 2 3 6 6 6 0 E1 N-terminal domain TPR_8 PF13181.6 KIK36821.1 - 0.13 12.6 0.3 46 4.6 0.0 5.2 7 0 0 7 7 7 0 Tetratricopeptide repeat CAAX_1 PF15895.5 KIK36821.1 - 0.44 10.4 12.0 13 5.6 0.2 5.1 3 2 3 6 6 6 0 CAAX box cerebral protein 1 DUF5102 PF17104.5 KIK36821.1 - 1.3 9.0 5.8 44 4.0 0.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF5102) TPR_2 PF07719.17 KIK36821.1 - 8.6 6.8 9.1 14 6.1 0.0 5.9 10 0 0 10 10 8 0 Tetratricopeptide repeat Rad60-SLD PF11976.8 KIK36824.1 - 4.4e-12 45.7 0.1 5.4e-12 45.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KIK36824.1 - 1.7e-07 30.9 0.0 2.1e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.8 KIK36824.1 - 0.028 14.6 0.0 0.036 14.3 0.0 1.2 1 0 0 1 1 1 0 TUG ubiquitin-like domain TFIIS_M PF07500.14 KIK36825.1 - 2.4e-31 108.5 0.1 2.4e-31 108.5 0.1 2.2 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KIK36825.1 - 6e-18 64.4 9.6 1.1e-17 63.6 9.6 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KIK36825.1 - 3.1e-10 39.9 0.9 3.1e-10 39.9 0.9 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.8 KIK36825.1 - 0.089 12.5 0.1 0.44 10.3 0.1 2.0 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain WD40 PF00400.32 KIK36826.1 - 1.1e-42 143.2 17.0 3.6e-08 33.9 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36826.1 - 0.00022 21.5 0.3 1.5 9.1 0.1 4.4 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK36826.1 - 0.018 13.7 0.3 3 6.4 0.0 3.2 1 1 2 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK36826.1 - 0.24 10.7 0.0 0.68 9.2 0.0 1.8 2 1 0 2 2 2 0 WD40-like domain Sacchrp_dh_C PF16653.5 KIK36827.1 - 0.057 13.5 1.3 0.063 13.4 1.3 1.0 1 0 0 1 1 1 0 Saccharopine dehydrogenase C-terminal domain GPI2 PF06432.11 KIK36827.1 - 0.081 12.4 1.4 0.097 12.1 1.4 1.0 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase Acetyltransf_3 PF13302.7 KIK36828.1 - 1.1e-10 42.3 0.0 1.5e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Mito_carr PF00153.27 KIK36829.1 - 6.3e-19 67.7 9.8 3.7e-09 36.4 0.5 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S30AE PF02482.19 KIK36830.1 - 0.16 12.8 0.3 16 6.4 0.0 2.2 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein KDZ PF18758.1 KIK36831.1 - 3.9e-15 56.1 0.8 4.5e-15 55.9 0.1 1.5 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase DUF5432 PF17497.2 KIK36834.1 - 0.04 14.0 0.1 0.044 13.9 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5432) GST_C_2 PF13410.6 KIK36834.1 - 0.14 12.2 0.1 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DDE_Tnp_4 PF13359.6 KIK36835.1 - 0.00019 21.1 0.0 0.21 11.2 0.0 2.7 1 1 2 3 3 3 2 DDE superfamily endonuclease Dynein_heavy PF03028.15 KIK36836.1 - 9e-07 29.0 0.0 1.4e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Transketolase_N PF00456.21 KIK36836.1 - 0.021 13.8 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Sirohm_synth_C PF14823.6 KIK36836.1 - 0.13 12.0 0.0 0.55 9.9 0.0 1.9 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal LIM_bind PF01803.16 KIK36838.1 - 5.8e-28 98.0 0.1 6.8e-28 97.8 0.1 1.0 1 0 0 1 1 1 1 LIM-domain binding protein DDE_1 PF03184.19 KIK36842.1 - 0.064 12.9 0.1 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KIK36842.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain WD40 PF00400.32 KIK36843.1 - 2.9e-135 436.1 43.8 2.9e-10 40.6 0.3 14.7 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36843.1 - 9e-51 170.1 0.0 0.0048 17.2 0.0 14.1 1 1 12 14 14 14 12 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK36843.1 - 6.1e-33 114.2 13.1 0.019 13.9 0.0 13.9 8 4 3 14 14 14 11 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK36843.1 - 1.8e-17 62.8 30.5 0.96 9.5 0.0 14.1 15 0 0 15 15 15 7 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK36843.1 - 2.4e-13 50.1 0.0 0.0013 18.2 0.0 8.6 9 2 2 11 11 11 2 WD40-like domain Nup160 PF11715.8 KIK36843.1 - 2e-10 40.0 5.8 3.1 6.3 0.0 10.4 6 3 4 12 12 12 3 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK36843.1 - 3.3e-07 29.9 9.6 6.2 6.1 0.0 9.9 9 2 3 12 12 12 2 Neuroblastoma-amplified sequence, N terminal DUF4072 PF13284.6 KIK36843.1 - 5.6e-07 29.9 2.3 9.3 6.8 0.0 8.7 9 0 0 9 9 9 1 Domain of unknown function (DUF4072) Frtz PF11768.8 KIK36843.1 - 4.3e-06 25.3 0.0 5.6 5.2 0.0 6.8 3 2 6 9 9 9 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_3 PF15911.5 KIK36843.1 - 2.3e-05 24.3 2.3 1.2e+02 2.8 0.0 9.3 12 1 0 12 12 12 0 WD domain, G-beta repeat Peptidase_S9_N PF02897.15 KIK36843.1 - 4.1e-05 22.6 0.0 10 4.8 0.0 6.6 3 3 6 9 9 9 1 Prolyl oligopeptidase, N-terminal beta-propeller domain PQQ PF01011.21 KIK36843.1 - 0.0046 16.8 0.5 5 7.2 0.0 5.5 6 0 0 6 6 6 1 PQQ enzyme repeat Cuticle_4 PF15955.5 KIK36843.1 - 0.009 16.7 0.9 3.7e+02 1.9 0.0 7.0 11 0 0 11 11 9 0 Cuticle protein DPPIV_N PF00930.21 KIK36843.1 - 0.13 11.0 0.4 1.2e+02 1.3 0.0 5.1 6 2 1 7 7 7 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ_2 PF13360.6 KIK36843.1 - 0.15 11.6 23.7 0.052 13.1 6.7 4.4 1 1 2 3 3 3 0 PQQ-like domain DUF5570 PF17731.1 KIK36843.1 - 2.7 8.1 24.3 41 4.3 0.1 8.5 3 3 6 9 9 9 0 Family of unknown function (DUF5570) RasGEF_N PF00618.20 KIK36845.1 - 0.0091 16.2 0.0 0.011 16.0 0.0 1.1 1 0 0 1 1 1 1 RasGEF N-terminal motif Abhydrolase_1 PF00561.20 KIK36849.1 - 1e-16 61.4 0.0 1.3e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK36849.1 - 1.7e-11 43.9 0.0 4.5e-11 42.5 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIK36849.1 - 2.3e-11 44.7 0.0 2.8e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KIK36849.1 - 2.4e-06 27.9 0.0 3.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain AMP-binding PF00501.28 KIK36850.1 - 6.7e-96 321.5 0.3 9.9e-96 320.9 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK36850.1 - 7.8e-25 87.7 0.4 5.3e-24 85.0 0.1 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KIK36850.1 - 8.8e-13 48.0 0.9 3.1e-12 46.2 0.4 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus SASP PF00269.20 KIK36854.1 - 0.028 14.4 0.2 0.067 13.2 0.2 1.8 1 1 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type SGT1 PF07093.11 KIK36854.1 - 0.037 12.5 1.5 0.047 12.1 1.5 1.1 1 0 0 1 1 1 0 SGT1 protein DUF2390 PF09523.10 KIK36854.1 - 0.064 13.6 1.0 0.11 12.8 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) Abhydrolase_6 PF12697.7 KIK36856.1 - 1.1e-12 49.1 0.2 1.3e-12 48.8 0.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK36856.1 - 2.7e-09 36.6 0.0 3.3e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK36856.1 - 4.9e-07 29.7 0.5 0.0003 20.5 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KIK36856.1 - 7.9e-05 22.5 0.1 0.4 10.4 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thioesterase PF00975.20 KIK36856.1 - 0.0021 18.2 0.0 0.05 13.7 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain Ser_hydrolase PF06821.13 KIK36856.1 - 0.087 12.7 0.0 0.89 9.4 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase UPF0227 PF05728.12 KIK36856.1 - 0.12 12.3 0.1 3.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) FSH1 PF03959.13 KIK36856.1 - 0.16 11.6 0.0 2.4 7.7 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DUF805 PF05656.14 KIK36857.1 - 0.72 10.3 6.9 7 7.1 6.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF805) Asp_protease_2 PF13650.6 KIK36858.1 - 0.00011 22.8 0.0 0.00035 21.1 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK36858.1 - 0.00016 22.2 0.0 0.00043 20.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KIK36858.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Fer4_2 PF12797.7 KIK36860.1 - 4.7 7.5 8.2 2.4 8.4 0.7 2.8 3 0 0 3 3 3 0 4Fe-4S binding domain WAPL PF07814.13 KIK36861.1 - 0.076 11.8 0.0 0.31 9.8 0.0 1.8 2 0 0 2 2 2 0 Wings apart-like protein regulation of heterochromatin MTBP_C PF14920.6 KIK36861.1 - 0.59 9.8 4.1 0.9 9.2 0.1 2.1 2 0 0 2 2 2 0 MDM2-binding Plavaka PF18759.1 KIK36862.1 - 5.9e-34 117.8 0.0 1.1e-33 116.9 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase Fas_alpha_ACP PF18325.1 KIK36865.1 - 4.1e-34 118.3 0.0 9.6e-34 117.1 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 KIK36865.1 - 6e-26 91.3 0.0 1.4e-14 54.2 0.0 2.5 2 0 0 2 2 2 2 Fatty acid synthase type I helical domain Acyl_transf_1 PF00698.21 KIK36865.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase domain LRRC37 PF15779.5 KIK36865.1 - 0.06 13.7 0.2 0.06 13.7 0.2 2.8 4 0 0 4 4 4 0 Leucine-rich repeat-containing protein 37 family WD40 PF00400.32 KIK36868.1 - 2.2e-19 69.4 7.4 4.1e-05 24.3 0.0 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK36868.1 - 4.1e-13 49.4 0.1 1.5e-06 28.4 0.0 3.4 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK36868.1 - 0.026 13.2 0.0 0.7 8.5 0.0 2.2 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KIK36868.1 - 0.11 11.2 0.0 1.3 7.7 0.0 2.0 1 1 1 2 2 2 0 Nup133 N terminal like F-box-like PF12937.7 KIK36869.1 - 8.5e-08 32.0 0.0 3.4e-07 30.0 0.0 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK36869.1 - 0.024 14.5 1.1 13 5.8 0.1 3.3 3 0 0 3 3 3 0 F-box domain 2-oxogl_dehyd_N PF16078.5 KIK36869.1 - 0.18 11.4 3.8 0.42 10.2 2.0 2.5 2 0 0 2 2 2 0 2-oxoglutarate dehydrogenase N-terminus WD40 PF00400.32 KIK36870.1 - 1.3e-06 29.0 6.2 0.00053 20.8 0.1 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat F-box-like PF12937.7 KIK36871.1 - 1.3e-06 28.2 2.1 0.0005 19.9 0.1 3.2 3 0 0 3 3 3 2 F-box-like F-box PF00646.33 KIK36871.1 - 0.0038 17.1 1.6 2.9 7.9 0.0 3.2 3 0 0 3 3 3 2 F-box domain DUF5533 PF17685.1 KIK36872.1 - 0.0026 18.2 0.7 0.0038 17.6 0.7 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5533) ALG11_N PF15924.5 KIK36874.1 - 2.9e-84 282.3 0.1 4.2e-84 281.8 0.1 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KIK36874.1 - 8.2e-22 77.5 0.0 1.2e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIK36874.1 - 1.2e-11 45.1 0.0 2.7e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KIK36874.1 - 0.04 14.3 0.0 0.096 13.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 FMN_dh PF01070.18 KIK36876.1 - 2.1e-110 369.0 0.1 2.6e-110 368.7 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 KIK36876.1 - 9.3e-09 34.9 0.3 0.002 17.5 0.3 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 KIK36876.1 - 4.4e-05 22.7 4.0 0.0033 16.5 1.7 3.1 2 1 1 3 3 3 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KIK36876.1 - 0.00024 20.4 0.2 0.00037 19.8 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase AAA PF00004.29 KIK36877.1 - 2.7e-38 131.4 0.0 7e-38 130.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIK36877.1 - 2e-10 40.3 0.1 5.1e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KIK36877.1 - 3.4e-06 27.5 0.3 7.8e-05 23.1 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KIK36877.1 - 3.6e-06 26.8 0.0 7.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KIK36877.1 - 3.4e-05 23.8 0.1 0.00026 21.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KIK36877.1 - 0.00012 22.3 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK36877.1 - 0.00021 21.6 0.3 0.0032 17.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 KIK36877.1 - 0.00024 21.3 0.0 0.0029 17.7 0.0 2.4 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KIK36877.1 - 0.00044 20.3 0.0 0.0017 18.4 0.0 2.1 3 0 0 3 3 1 1 AAA domain Mg_chelatase PF01078.21 KIK36877.1 - 0.00054 19.4 0.1 0.0024 17.3 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KIK36877.1 - 0.00062 20.3 0.0 0.0014 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KIK36877.1 - 0.00069 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 KIK36877.1 - 0.0014 18.8 0.0 0.014 15.5 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.22 KIK36877.1 - 0.0018 18.7 0.0 0.0056 17.0 0.0 1.9 2 0 0 2 2 1 1 RNA helicase Rad17 PF03215.15 KIK36877.1 - 0.0024 17.8 0.1 0.0055 16.6 0.0 1.7 2 0 0 2 2 1 1 Rad17 P-loop domain TniB PF05621.11 KIK36877.1 - 0.003 17.0 0.0 2.1 7.7 0.0 2.4 1 1 1 2 2 2 2 Bacterial TniB protein IstB_IS21 PF01695.17 KIK36877.1 - 0.0037 17.0 0.0 0.0074 16.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 KIK36877.1 - 0.0037 17.5 0.4 0.0091 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KIK36877.1 - 0.0049 16.6 0.0 0.0092 15.7 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 KIK36877.1 - 0.0073 16.2 0.1 0.017 15.1 0.1 1.6 1 0 0 1 1 1 1 NACHT domain TIP49 PF06068.13 KIK36877.1 - 0.011 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Zeta_toxin PF06414.12 KIK36877.1 - 0.014 14.7 0.1 0.026 13.8 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 KIK36877.1 - 0.017 14.8 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 KIK36877.1 - 0.021 15.1 0.1 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_25 PF13481.6 KIK36877.1 - 0.023 14.3 0.1 0.083 12.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KIK36877.1 - 0.027 14.9 0.0 0.081 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KIK36877.1 - 0.034 13.9 0.0 0.1 12.3 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KIK36877.1 - 0.04 13.0 0.1 0.1 11.7 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 KIK36877.1 - 0.062 12.8 0.0 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KIK36877.1 - 0.076 12.9 0.1 0.2 11.5 0.0 1.7 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KIK36877.1 - 0.085 13.4 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter SKI PF01202.22 KIK36877.1 - 0.12 12.5 0.2 0.41 10.8 0.0 1.9 2 0 0 2 2 2 0 Shikimate kinase AAA_3 PF07726.11 KIK36877.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GBR2_CC PF18455.1 KIK36878.1 - 0.062 13.4 0.8 0.16 12.1 0.8 1.7 1 0 0 1 1 1 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain AA_kinase PF00696.28 KIK36881.1 - 0.21 11.2 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Amino acid kinase family NARP1 PF12569.8 KIK36884.1 - 1.3e-140 469.7 8.5 2.1e-139 465.8 2.8 2.9 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 KIK36884.1 - 3e-12 46.9 3.7 0.51 10.9 0.5 7.3 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIK36884.1 - 1.1e-11 43.9 18.1 0.15 12.2 0.1 8.4 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KIK36884.1 - 1.5e-11 44.1 10.7 0.0058 17.4 0.1 9.1 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK36884.1 - 3e-09 37.4 8.2 0.068 13.8 2.4 7.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK36884.1 - 4.5e-09 35.8 0.8 0.00044 19.9 0.1 4.7 4 0 0 4 4 4 1 TPR repeat TPR_1 PF00515.28 KIK36884.1 - 4.5e-08 32.6 8.3 0.024 14.4 0.1 6.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIK36884.1 - 6.1e-08 32.5 0.5 0.46 11.0 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIK36884.1 - 2.1e-06 27.8 8.4 0.07 13.3 0.9 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 KIK36884.1 - 4.9e-06 26.7 5.8 0.7 10.7 0.2 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK36884.1 - 3.3e-05 24.1 9.8 0.14 12.5 0.1 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK36884.1 - 5.2e-05 23.0 6.0 0.42 10.7 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK36884.1 - 0.0019 17.6 3.9 0.038 13.4 0.0 3.7 3 1 0 4 4 4 1 MalT-like TPR region TPR_8 PF13181.6 KIK36884.1 - 0.0027 17.8 15.0 13 6.3 0.1 7.6 9 0 0 9 9 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK36884.1 - 0.0027 17.9 10.1 1.1 9.5 0.0 5.8 5 2 2 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 HrpB1_HrpK PF09613.10 KIK36884.1 - 0.014 15.1 1.2 14 5.3 0.0 4.2 4 1 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) BTAD PF03704.17 KIK36884.1 - 0.021 15.3 3.0 0.39 11.2 0.7 3.0 2 0 0 2 2 2 0 Bacterial transcriptional activator domain SPO22 PF08631.10 KIK36884.1 - 0.026 14.0 1.3 0.29 10.6 0.0 2.9 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like TPR_6 PF13174.6 KIK36884.1 - 0.027 15.1 12.6 7.1 7.5 0.1 6.9 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIK36884.1 - 0.56 10.2 3.3 41 4.2 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat HEAT PF02985.22 KIK36885.1 - 2.1e-05 24.4 0.6 11 6.7 0.0 5.4 5 0 0 5 5 5 3 HEAT repeat Cnd1 PF12717.7 KIK36885.1 - 0.0031 17.6 8.2 0.053 13.6 0.0 4.6 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIK36885.1 - 0.0073 16.7 10.4 0.29 11.5 0.0 6.1 4 2 4 8 8 8 3 HEAT repeats CBP_BcsN PF17038.5 KIK36886.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsN Tmpp129 PF10272.9 KIK36888.1 - 0.22 10.8 1.8 0.33 10.2 1.8 1.4 1 0 0 1 1 1 0 Putative transmembrane protein precursor DUF3328 PF11807.8 KIK36889.1 - 1.8e-13 50.8 7.3 4.6e-13 49.5 7.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) VMA21 PF09446.10 KIK36890.1 - 1.1e-10 41.5 7.6 1.7e-10 40.9 7.6 1.3 1 0 0 1 1 1 1 VMA21-like domain DUF2269 PF10027.9 KIK36890.1 - 0.017 15.1 0.1 0.019 15.0 0.1 1.0 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) Actin PF00022.19 KIK36891.1 - 3.8e-148 493.4 0.0 2.5e-147 490.8 0.0 1.8 1 1 0 1 1 1 1 Actin DUF3328 PF11807.8 KIK36892.1 - 2e-10 40.8 0.6 6.1e-10 39.2 0.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) But2 PF09792.9 KIK36893.1 - 0.00066 20.1 0.0 0.0011 19.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF3577 PF12101.8 KIK36894.1 - 0.079 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3577) Acetyltransf_1 PF00583.25 KIK36895.1 - 1.1e-09 38.5 0.0 1.4e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK36895.1 - 3.6e-08 33.4 0.0 6.2e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK36895.1 - 4.9e-07 30.1 0.0 8.6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK36895.1 - 0.0053 16.7 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_13 PF13880.6 KIK36895.1 - 0.029 14.4 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase MOZ_SAS PF01853.18 KIK36895.1 - 0.03 14.0 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_CG PF14542.6 KIK36895.1 - 0.043 14.0 0.0 0.087 13.0 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Retrotran_gag_2 PF14223.6 KIK36897.1 - 4.8e-11 42.5 0.0 5.9e-11 42.2 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DpnI_C PF17726.1 KIK36897.1 - 0.019 15.1 0.3 0.026 14.7 0.3 1.2 1 0 0 1 1 1 0 Dam-replacing HTH domain DUF4219 PF13961.6 KIK36898.1 - 0.0005 19.7 0.3 0.0011 18.5 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 KIK36898.1 - 0.039 13.8 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type p450 PF00067.22 KIK36899.1 - 3.4e-61 207.4 0.0 4.8e-32 111.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KIK36900.1 - 8e-65 219.4 0.0 9.1e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4470 PF14737.6 KIK36901.1 - 1.3e-24 86.2 0.0 2.9e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KIK36901.1 - 2.5e-11 43.5 10.5 7.7e-11 41.9 10.5 1.9 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIK36901.1 - 0.24 11.7 6.6 0.83 10.0 6.6 1.9 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Cornichon PF03311.14 KIK36904.1 - 4e-53 178.9 9.4 4.7e-53 178.7 9.4 1.0 1 0 0 1 1 1 1 Cornichon protein RRM_1 PF00076.22 KIK36906.1 - 1.9e-05 24.4 0.0 3.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.22 KIK36907.1 - 2.6e-66 224.3 0.0 3.3e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4470 PF14737.6 KIK36909.1 - 2e-25 88.8 0.0 4e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KIK36909.1 - 2.7e-11 43.4 10.5 7.7e-11 41.9 10.5 1.9 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIK36909.1 - 0.044 14.1 3.9 0.13 12.6 3.9 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 KIK36909.1 - 5.5 7.0 9.2 26 4.8 9.2 2.2 1 1 0 1 1 1 0 HIT zinc finger DUF4470 PF14737.6 KIK36911.1 - 6.3e-25 87.2 0.1 1.5e-24 86.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KIK36911.1 - 7.1e-12 45.2 11.5 2e-11 43.8 11.5 1.8 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIK36911.1 - 0.13 12.6 9.7 0.19 12.0 7.0 2.6 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Integrase_H2C2 PF17921.1 KIK36916.1 - 4.7e-11 42.6 5.9 4.7e-11 42.6 5.9 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain Tk-SP_N-pro PF18237.1 KIK36919.1 - 0.035 14.1 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Tk-SP N-propeptide domain Glyco_hydro_1 PF00232.18 KIK36924.1 - 9.1e-10 37.5 0.0 1e-09 37.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 WD40 PF00400.32 KIK36925.1 - 6.9e-08 33.0 0.2 7.9e-08 32.8 0.2 1.1 1 0 0 1 1 1 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KIK36925.1 - 0.026 13.5 0.0 0.026 13.5 0.0 1.0 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KIK36925.1 - 0.033 14.5 0.0 0.037 14.3 0.0 1.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain p450 PF00067.22 KIK36926.1 - 5.3e-19 68.3 0.2 5.5e-19 68.3 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 BST2 PF16716.5 KIK36927.1 - 2.7 8.6 23.3 3.8 8.2 4.3 4.4 3 2 1 4 4 4 0 Bone marrow stromal antigen 2 Crust_neuro_H PF03858.13 KIK36928.1 - 0.18 12.7 0.0 0.35 11.7 0.0 1.4 1 0 0 1 1 1 0 Crustacean neurohormone H Ferrochelatase PF00762.19 KIK36935.1 - 0.092 11.8 0.0 0.092 11.8 0.0 1.0 1 0 0 1 1 1 0 Ferrochelatase Pyridoxal_deC PF00282.19 KIK36937.1 - 4.3e-105 351.5 0.0 5.1e-105 351.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF5103 PF17116.5 KIK36937.1 - 0.11 11.7 0.0 0.81 8.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5103) ATE_N PF04376.13 KIK36938.1 - 0.67 10.4 3.5 1.8 9.0 2.0 2.5 1 1 1 2 2 2 0 Arginine-tRNA-protein transferase, N terminus Pyridoxal_deC PF00282.19 KIK36940.1 - 3e-94 315.8 0.0 3.3e-93 312.4 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 KIK36940.1 - 0.13 11.5 0.0 0.78 8.8 0.0 2.1 2 1 1 3 3 3 0 Aminotransferase class I and II DAO PF01266.24 KIK36941.1 - 4.3e-35 121.9 0.3 5.3e-35 121.6 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIK36941.1 - 0.0083 16.1 0.1 0.021 14.8 0.2 1.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KIK36941.1 - 0.026 14.7 0.2 0.099 12.9 0.2 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain SAM_KSR1 PF13543.6 KIK36941.1 - 0.2 11.8 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 DUF563 PF04577.14 KIK36942.1 - 7.5e-19 68.7 0.0 7.5e-19 68.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF563) TPM_phosphatase PF04536.14 KIK36942.1 - 0.036 14.2 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 TPM domain MA3 PF02847.17 KIK36942.1 - 0.18 11.8 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 MA3 domain zf-C2H2 PF00096.26 KIK36943.1 - 3.1e-15 55.7 86.5 0.018 15.4 2.5 10.5 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK36943.1 - 4.5e-11 42.6 73.2 0.015 16.1 0.5 10.5 10 0 0 10 10 10 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK36943.1 - 2.4e-07 30.9 1.9 1.3e-06 28.5 0.6 11.4 10 2 1 11 11 11 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KIK36943.1 - 0.00014 22.0 34.8 0.11 12.8 0.6 7.6 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KIK36943.1 - 0.00045 20.1 0.3 0.00045 20.1 0.3 7.5 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KIK36943.1 - 0.0019 18.4 35.0 0.27 11.5 4.2 5.6 2 1 3 5 5 5 5 C2H2-type zinc ribbon Antimicrobial_6 PF08036.11 KIK36943.1 - 0.015 15.3 0.7 0.015 15.3 0.7 2.5 2 0 0 2 2 2 0 Diapausin family of antimicrobial peptide zf_UBZ PF18439.1 KIK36943.1 - 0.49 10.0 8.5 4.8 6.9 0.2 4.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Myb_DNA-binding PF00249.31 KIK36945.1 - 0.021 15.0 0.0 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Carn_acyltransf PF00755.20 KIK36945.1 - 0.038 12.6 0.0 0.067 11.8 0.0 1.3 1 0 0 1 1 1 0 Choline/Carnitine o-acyltransferase DUF1658 PF07871.11 KIK36951.1 - 0.15 12.1 1.3 0.45 10.5 1.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) MFS_1 PF07690.16 KIK36953.1 - 2.2e-19 69.6 55.1 7.7e-14 51.4 31.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L16 PF00252.18 KIK36956.1 - 1.5e-46 157.7 0.0 1.9e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e p450 PF00067.22 KIK36957.1 - 1.3e-71 241.8 0.0 1.6e-71 241.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rad1 PF02144.16 KIK36958.1 - 1e-73 247.8 0.0 1.2e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Histone PF00125.24 KIK36958.1 - 0.13 12.6 0.3 1.3 9.4 0.0 2.1 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Biotin_lipoyl PF00364.22 KIK36959.1 - 2.2e-19 69.1 0.4 4.4e-19 68.1 0.4 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KIK36959.1 - 1.2e-05 25.5 0.1 3.4e-05 24.1 0.1 1.8 1 0 0 1 1 1 1 e3 binding domain DUF2486 PF10667.9 KIK36959.1 - 2.6 8.2 9.1 0.36 11.0 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) HSA PF07529.13 KIK36960.1 - 1.6e-11 44.3 0.2 1.6e-11 44.3 0.2 3.0 2 0 0 2 2 2 1 HSA Myb_DNA-bind_6 PF13921.6 KIK36960.1 - 2.6e-09 37.2 0.1 7.8e-09 35.7 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KIK36960.1 - 0.00017 21.7 0.3 0.00048 20.3 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain FOXP-CC PF16159.5 KIK36961.1 - 0.033 14.8 0.5 0.24 12.1 0.0 2.3 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 KIK36961.1 - 0.34 11.5 2.7 0.76 10.3 0.1 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2 PF00096.26 KIK36962.1 - 0.0099 16.3 0.2 0.0099 16.3 0.2 3.3 3 0 0 3 3 3 1 Zinc finger, C2H2 type DUF1281 PF06924.11 KIK36962.1 - 0.088 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) DUF2576 PF10845.8 KIK36962.1 - 0.21 11.2 0.4 0.21 11.2 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2576) CNOT1_CAF1_bind PF16415.5 KIK36963.1 - 5.1e-91 304.1 1.0 5e-89 297.5 0.2 2.7 3 0 0 3 3 3 2 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 KIK36963.1 - 1.1e-51 174.7 0.0 2.4e-51 173.6 0.0 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KIK36963.1 - 1.1e-45 155.4 1.2 2e-45 154.5 0.4 2.0 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF3819 PF12842.7 KIK36963.1 - 5e-39 133.6 0.2 1.2e-37 129.1 0.1 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF3819) FdhE PF04216.12 KIK36963.1 - 0.11 12.4 0.1 0.38 10.6 0.1 2.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation MRP-L20 PF12824.7 KIK36965.1 - 1.6e-19 70.7 7.1 3.8e-19 69.4 7.1 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_7 PF02796.15 KIK36965.1 - 0.084 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Phage_NinH PF06322.11 KIK36965.1 - 0.2 11.5 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Phage NinH protein Plavaka PF18759.1 KIK36966.1 - 3.7e-36 125.0 0.0 5.9e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase SDA1 PF05285.12 KIK36966.1 - 0.023 14.1 2.3 0.04 13.3 2.3 1.3 1 0 0 1 1 1 0 SDA1 DUF1666 PF07891.12 KIK36966.1 - 0.055 13.1 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) DUF5446 PF17522.2 KIK36967.1 - 0.3 11.3 2.5 0.72 10.1 2.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) Cas_GSU0054 PF09609.10 KIK36971.1 - 0.083 11.6 0.2 0.092 11.4 0.2 1.0 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) NBP1 PF08537.10 KIK36972.1 - 0.0064 15.9 7.5 0.0071 15.8 7.5 1.0 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 NinG PF05766.12 KIK36972.1 - 0.083 12.8 5.6 0.092 12.7 5.6 1.2 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DDRGK PF09756.9 KIK36972.1 - 0.6 9.7 14.7 0.69 9.5 14.7 1.1 1 0 0 1 1 1 0 DDRGK domain RAP1 PF07218.11 KIK36972.1 - 0.73 8.0 2.9 0.83 7.9 2.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Spc7_N PF15402.6 KIK36972.1 - 1.5 7.0 16.3 1.6 6.9 16.3 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Auts2 PF15336.6 KIK36972.1 - 1.7 8.7 15.5 2.2 8.4 15.5 1.1 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Presenilin PF01080.17 KIK36972.1 - 3 6.5 3.7 3.1 6.5 3.7 1.0 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 KIK36972.1 - 4.2 7.1 5.0 4.3 7.0 5.0 1.1 1 0 0 1 1 1 0 Connexin CDC45 PF02724.14 KIK36972.1 - 7 4.8 9.5 7.1 4.8 9.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Apis_Csd PF11671.8 KIK36972.1 - 7.7 6.5 13.1 9.4 6.2 13.1 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein Pox_Ag35 PF03286.14 KIK36973.1 - 1.3 8.8 7.1 2.4 7.9 7.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CENP-B_dimeris PF09026.10 KIK36973.1 - 1.9 9.0 11.4 4.2 7.8 11.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BUD22 PF09073.10 KIK36973.1 - 4.4 6.5 11.5 6.7 5.9 11.5 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 KIK36973.1 - 6.6 6.1 12.4 9.3 5.6 12.4 1.1 1 0 0 1 1 1 0 SDA1 Nnf1 PF03980.14 KIK36975.1 - 0.049 14.0 1.9 0.77 10.2 0.1 2.7 3 0 0 3 3 3 0 Nnf1 DUF2937 PF11157.8 KIK36975.1 - 0.2 11.3 0.9 0.49 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF3007 PF11460.8 KIK36977.1 - 0.27 11.5 1.7 0.63 10.3 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) YbhQ PF11076.8 KIK36977.1 - 1.8 8.6 9.5 0.21 11.6 4.6 1.9 2 0 0 2 2 2 0 Putative inner membrane protein YbhQ DUF5062 PF16691.5 KIK36978.1 - 0.063 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5062) Oxysterol_BP PF01237.18 KIK36980.1 - 3.2e-42 144.7 0.4 2.3e-25 89.2 0.1 2.9 2 1 0 2 2 2 2 Oxysterol-binding protein DUF5589 PF17672.1 KIK36980.1 - 0.049 13.6 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5589) Adeno_E3_CR2 PF02439.15 KIK36984.1 - 0.00015 21.5 0.1 0.00029 20.5 0.1 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Glycophorin_A PF01102.18 KIK36984.1 - 0.13 12.5 3.6 0.6 10.4 0.0 2.6 2 0 0 2 2 2 0 Glycophorin A CD34_antigen PF06365.12 KIK36984.1 - 0.18 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family CorA PF01544.18 KIK36985.1 - 7.6e-09 35.3 4.4 1.3e-08 34.5 4.4 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein FleQ PF06490.11 KIK36985.1 - 0.045 14.1 2.2 0.52 10.7 0.6 2.7 3 0 0 3 3 3 0 Flagellar regulatory protein FleQ PhoU PF01895.19 KIK36985.1 - 0.25 11.8 3.8 0.24 11.9 2.0 2.0 2 0 0 2 2 2 0 PhoU domain AAA PF00004.29 KIK36988.1 - 1e-43 148.9 0.0 1.9e-43 148.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIK36988.1 - 1.1e-12 47.5 0.1 2.7e-12 46.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KIK36988.1 - 4e-08 33.6 0.0 8.9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KIK36988.1 - 2.1e-06 27.8 0.0 7.6e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIK36988.1 - 6.7e-06 26.6 0.1 8.3e-05 23.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 KIK36988.1 - 7.6e-06 25.8 0.2 1.7e-05 24.7 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 KIK36988.1 - 3.5e-05 24.1 1.1 0.0059 16.9 0.1 2.6 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 KIK36988.1 - 6.3e-05 22.8 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KIK36988.1 - 0.00048 20.7 0.2 0.017 15.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 KIK36988.1 - 0.00097 18.4 0.0 0.0021 17.3 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KIK36988.1 - 0.0014 18.8 0.0 0.0032 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIK36988.1 - 0.002 17.9 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 KIK36988.1 - 0.0052 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KIK36988.1 - 0.0056 16.4 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KIK36988.1 - 0.0077 15.6 0.1 0.019 14.4 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KIK36988.1 - 0.0085 15.6 0.0 0.14 11.6 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.6 KIK36988.1 - 0.0094 16.2 0.3 0.021 15.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 KIK36988.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KIK36988.1 - 0.016 14.5 0.0 0.037 13.4 0.0 1.6 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 KIK36988.1 - 0.02 14.6 0.1 0.098 12.4 0.0 2.1 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KIK36988.1 - 0.026 14.1 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 KIK36988.1 - 0.026 13.7 0.0 0.054 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 KIK36988.1 - 0.028 14.4 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2072 PF09845.9 KIK36988.1 - 0.041 14.1 0.1 0.085 13.1 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein RNA_helicase PF00910.22 KIK36988.1 - 0.042 14.2 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KIK36988.1 - 0.061 12.9 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KIK36988.1 - 0.062 12.4 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 KIK36988.1 - 0.097 11.9 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 KIK36988.1 - 0.1 13.0 0.1 0.58 10.5 0.1 2.2 3 0 0 3 3 3 0 AAA domain DUF5406 PF17400.2 KIK36988.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5406) AAA_11 PF13086.6 KIK36988.1 - 0.14 11.9 0.2 0.4 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KIK36988.1 - 0.15 11.6 0.3 19 4.8 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pro-kuma_activ PF09286.11 KIK36992.1 - 1.7e-16 60.8 0.0 1.7e-15 57.6 0.0 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain AAA_22 PF13401.6 KIK36992.1 - 0.0017 18.7 0.0 0.0026 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Dynamin_M PF01031.20 KIK36993.1 - 1e-24 87.2 0.0 1.2e-24 87.1 0.0 1.0 1 0 0 1 1 1 1 Dynamin central region Hyr1 PF15789.5 KIK36995.1 - 7.4 6.2 8.7 0.13 11.8 0.6 2.3 2 0 0 2 2 2 0 Hyphally regulated cell wall GPI-anchored protein 1 Plavaka PF18759.1 KIK36997.1 - 0.013 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Plavaka transposase XPB_DRD PF18458.1 KIK36997.1 - 0.15 12.0 0.1 0.4 10.6 0.1 1.7 2 0 0 2 2 2 0 Xeroderma pigmentosum group B helicase damage recognition domain NOA36 PF06524.12 KIK36998.1 - 3.8 6.7 10.8 8.2 5.7 10.8 1.5 1 0 0 1 1 1 0 NOA36 protein Peptidase_M24 PF00557.24 KIK36999.1 - 3.1e-09 36.8 0.2 3.9e-09 36.5 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Dsh_C PF12316.8 KIK37000.1 - 0.64 10.4 5.8 0.91 9.9 5.8 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Ras PF00071.22 KIK37006.1 - 1.6e-62 209.9 0.2 1.9e-62 209.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK37006.1 - 8.4e-35 119.6 0.1 1.2e-34 119.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK37006.1 - 9.9e-13 47.9 0.1 1.2e-12 47.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIK37006.1 - 4.1e-07 30.1 0.1 6e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIK37006.1 - 4.3e-05 23.1 0.2 0.00017 21.2 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIK37006.1 - 0.00016 21.6 0.3 0.02 14.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KIK37006.1 - 0.0017 18.6 0.1 0.021 15.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain SRPRB PF09439.10 KIK37006.1 - 0.0051 16.3 0.0 0.0081 15.6 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF3533 PF12051.8 KIK37006.1 - 0.0088 15.0 0.2 0.01 14.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) PduV-EutP PF10662.9 KIK37006.1 - 0.012 15.4 0.0 0.04 13.6 0.0 1.8 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 KIK37006.1 - 0.013 14.9 0.1 0.02 14.2 0.1 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region KAP_NTPase PF07693.14 KIK37006.1 - 0.018 14.3 0.0 0.032 13.5 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.6 KIK37006.1 - 0.019 15.4 0.1 0.032 14.6 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KIK37006.1 - 0.026 14.3 0.1 0.051 13.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIK37006.1 - 0.046 14.2 0.1 0.075 13.6 0.1 1.5 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 KIK37006.1 - 0.089 12.3 0.1 0.13 11.8 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 KIK37006.1 - 0.089 12.2 0.0 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 KIK37006.1 - 0.094 12.2 0.0 0.5 9.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region MCM PF00493.23 KIK37006.1 - 0.11 11.6 0.0 0.23 10.5 0.0 1.5 2 0 0 2 2 2 0 MCM P-loop domain YvfG PF09628.10 KIK37006.1 - 0.16 12.4 0.1 0.29 11.5 0.1 1.5 1 0 0 1 1 1 0 YvfG protein AAA_21 PF13304.6 KIK37006.1 - 0.17 11.6 1.0 0.33 10.7 0.6 1.6 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system rhaM PF05336.13 KIK37007.1 - 3.4e-33 113.9 0.0 3.8e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase rhaM PF05336.13 KIK37008.1 - 1.3e-31 108.8 0.1 1.5e-31 108.6 0.1 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase Senescence PF06911.12 KIK37013.1 - 1.2e-35 123.4 7.1 5.1e-35 121.4 7.1 1.9 1 1 0 1 1 1 1 Senescence-associated protein DUF1077 PF06417.12 KIK37014.1 - 6.7e-44 148.7 0.2 8.7e-44 148.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Ras PF00071.22 KIK37015.1 - 7.4e-53 178.5 0.0 8.6e-53 178.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK37015.1 - 6.4e-20 71.6 0.0 8.8e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK37015.1 - 5.9e-07 29.1 0.0 8.2e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIK37015.1 - 0.061 12.9 0.0 0.5 9.9 0.0 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ANAPC4_WD40 PF12894.7 KIK37016.1 - 1.3e-05 25.4 0.1 0.039 14.2 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK37016.1 - 0.00073 20.3 3.8 0.78 10.7 0.1 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat RdRP PF05183.12 KIK37017.1 - 9.5e-155 516.5 0.0 1.4e-154 515.9 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase WD40 PF00400.32 KIK37018.1 - 3.2e-20 72.1 11.1 4.2e-06 27.4 0.9 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37018.1 - 1e-10 41.8 4.6 0.0099 16.2 0.1 3.6 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KIK37018.1 - 0.0018 16.9 0.1 0.0025 16.4 0.1 1.2 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.8 KIK37018.1 - 0.11 11.1 4.1 2.1 6.9 0.1 3.3 2 1 2 4 4 4 0 Nucleoporin Nup120/160 T2SSB PF16537.5 KIK37018.1 - 0.17 11.5 0.0 0.43 10.2 0.0 1.6 1 0 0 1 1 1 0 Type II secretion system protein B RRG8 PF17068.5 KIK37020.1 - 0.025 14.0 0.1 0.029 13.8 0.1 1.1 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial WD40 PF00400.32 KIK37021.1 - 3.2e-39 132.2 19.5 6.7e-07 29.9 1.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37021.1 - 1.9e-17 63.3 7.2 0.00038 20.7 0.1 6.3 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK37021.1 - 1.1e-07 31.2 1.1 0.095 11.6 0.0 4.1 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK37021.1 - 1.1e-07 31.0 9.1 0.034 12.8 0.5 4.6 3 2 1 5 5 5 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KIK37021.1 - 0.00032 19.4 1.2 0.3 9.6 0.0 3.2 1 1 1 3 3 3 2 Cytochrome D1 heme domain WD40_like PF17005.5 KIK37021.1 - 0.0023 17.3 0.0 0.51 9.6 0.0 3.5 2 1 1 4 4 4 1 WD40-like domain Gmad1 PF10647.9 KIK37021.1 - 0.0027 17.5 1.1 0.014 15.2 0.8 2.2 2 1 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain potato_inhibit PF00280.18 KIK37021.1 - 0.086 13.5 0.0 6.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Potato inhibitor I family Pkinase PF00069.25 KIK37024.1 - 1.3e-06 28.0 0.1 8.9e-06 25.3 0.1 2.2 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK37024.1 - 0.002 17.4 0.0 0.0089 15.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase SET PF00856.28 KIK37025.1 - 5.2e-13 49.7 0.0 8.4e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 KIK37025.1 - 5e-09 36.1 10.1 5e-09 36.1 10.1 2.5 2 0 0 2 2 2 1 MYND finger WD40 PF00400.32 KIK37026.1 - 9.5e-37 124.4 20.0 3e-06 27.9 0.3 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37026.1 - 5.7e-16 58.6 7.3 0.0023 18.2 0.1 6.2 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK37026.1 - 2.7e-06 27.4 0.7 0.00056 19.8 0.1 2.9 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KIK37026.1 - 1.5e-05 23.7 0.0 0.0005 18.7 0.1 2.6 2 1 1 3 3 3 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KIK37026.1 - 1.7e-05 23.9 0.0 0.69 8.8 0.0 4.4 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK37026.1 - 0.00022 20.6 0.0 0.073 12.4 0.0 3.2 2 1 1 3 3 3 1 WD40-like domain Nup160 PF11715.8 KIK37026.1 - 0.0025 16.5 4.1 0.69 8.5 0.1 3.3 3 1 0 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK37026.1 - 0.0051 16.2 0.0 0.16 11.3 0.0 2.8 2 1 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KIK37026.1 - 0.0073 16.2 0.0 32 4.6 0.0 4.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 KIK37026.1 - 0.013 16.0 5.1 2.7 8.6 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain Sec31 PF11549.8 KIK37027.1 - 0.12 12.2 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein transport protein SEC31 AAA PF00004.29 KIK37028.1 - 1.9e-16 60.7 0.0 1.1e-15 58.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK37028.1 - 0.0028 17.9 1.1 0.078 13.3 0.4 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KIK37028.1 - 0.0045 17.0 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIK37028.1 - 0.0056 17.1 1.1 0.072 13.5 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KIK37028.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.12 KIK37028.1 - 0.17 11.2 0.0 0.37 10.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 KIK37029.1 - 2.6e-11 43.7 0.0 6.3e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK37029.1 - 8e-09 36.1 0.0 2.8e-08 34.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK37029.1 - 0.0048 17.3 0.0 0.016 15.6 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK37029.1 - 0.0065 16.7 0.0 0.019 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIK37029.1 - 0.015 15.7 0.0 0.041 14.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.17 KIK37029.1 - 0.02 14.7 0.0 0.052 13.3 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 KIK37029.1 - 0.023 14.6 0.0 0.065 13.1 0.0 1.8 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KIK37029.1 - 0.026 13.7 0.0 0.073 12.2 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain DUF1242 PF06842.12 KIK37029.1 - 0.043 13.6 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1242) AAA_17 PF13207.6 KIK37029.1 - 0.064 13.7 0.0 0.27 11.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK37029.1 - 0.075 13.2 0.0 0.25 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK37029.1 - 0.091 13.3 0.0 0.37 11.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIK37029.1 - 0.095 13.2 0.0 0.28 11.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.18 KIK37029.1 - 0.14 11.9 0.0 0.59 9.8 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 KIK37029.1 - 0.17 11.8 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.6 KIK37029.1 - 0.2 11.4 0.0 0.56 10.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.6 KIK37029.1 - 0.57 9.9 0.0 0.57 9.9 0.0 2.5 4 0 0 4 4 4 0 AAA domain Amino_oxidase PF01593.24 KIK37030.1 - 1.3e-39 136.8 0.0 4.2e-39 135.1 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK37030.1 - 9.6e-09 35.4 0.0 3e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Tnp_P_element PF12017.8 KIK37030.1 - 0.15 11.5 0.0 0.53 9.7 0.0 1.9 1 0 0 1 1 1 0 Transposase protein Waikav_capsid_1 PF12264.8 KIK37031.1 - 0.0062 16.1 1.3 0.011 15.2 1.3 1.4 1 0 0 1 1 1 1 Waikavirus capsid protein 1 APH PF01636.23 KIK37033.1 - 2.7e-12 47.1 0.1 3.8e-11 43.4 0.1 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family APOBEC1 PF18769.1 KIK37033.1 - 0.033 14.4 0.1 0.071 13.4 0.1 1.4 1 0 0 1 1 1 0 APOBEC1 F-box-like PF12937.7 KIK37035.1 - 6.8e-06 25.9 5.6 6.8e-06 25.9 5.6 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK37035.1 - 0.0027 17.6 4.6 0.0075 16.1 4.6 1.9 1 0 0 1 1 1 1 F-box domain MT PF12777.7 KIK37035.1 - 0.11 11.5 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor REV PF00424.18 KIK37035.1 - 0.4 10.7 3.6 0.34 11.0 0.1 2.6 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) TFIIA_gamma_N PF02268.16 KIK37036.1 - 3e-25 88.0 0.1 5e-25 87.3 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 KIK37036.1 - 2.4e-21 75.6 0.0 4e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Pro_isomerase PF00160.21 KIK37037.1 - 6.3e-31 107.8 0.0 7.4e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribonucleas_3_3 PF14622.6 KIK37038.1 - 1.3e-10 41.5 0.0 5.9e-10 39.4 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease-III-like XPC-binding PF09280.11 KIK37038.1 - 0.1 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 XPC-binding domain FHA PF00498.26 KIK37040.1 - 4.5e-09 36.5 0.0 5.6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIK37040.1 - 0.00042 20.6 0.0 0.00068 19.9 0.0 1.2 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Oxidored-like PF09791.9 KIK37041.1 - 6.9e-19 67.2 0.8 1.2e-18 66.4 0.8 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal PMEI PF04043.15 KIK37041.1 - 0.019 15.3 0.0 0.026 14.9 0.0 1.4 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Spectrin PF00435.21 KIK37041.1 - 0.049 14.1 0.2 10 6.6 0.0 2.3 2 1 0 2 2 2 0 Spectrin repeat YniB PF14002.6 KIK37043.1 - 0.077 12.8 1.3 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 YniB-like protein Myb_DNA-bind_3 PF12776.7 KIK37046.1 - 8e-12 46.0 0.2 1.1e-11 45.6 0.2 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KIK37046.1 - 1.8e-06 28.2 0.1 3.3e-06 27.4 0.1 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KIK37046.1 - 0.035 14.4 0.0 0.077 13.3 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SesA PF17107.5 KIK37046.1 - 0.052 13.7 0.0 0.1 12.8 0.0 1.6 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Myb_DNA-binding PF00249.31 KIK37046.1 - 0.12 12.5 0.0 0.94 9.7 0.0 2.4 3 0 0 3 3 3 0 Myb-like DNA-binding domain SET PF00856.28 KIK37048.1 - 1.5e-11 45.0 0.0 2.4e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 SET domain HTH_21 PF13276.6 KIK37048.1 - 0.00091 19.3 0.0 0.0021 18.2 0.0 1.6 1 0 0 1 1 1 1 HTH-like domain p450 PF00067.22 KIK37049.1 - 3.3e-68 230.5 0.0 9.6e-68 229.0 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 HLH PF00010.26 KIK37050.1 - 1.9e-14 53.3 0.2 3.6e-14 52.5 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nudix_N PF12535.8 KIK37050.1 - 0.15 11.7 0.6 0.3 10.7 0.6 1.4 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal PDZ_6 PF17820.1 KIK37051.1 - 0.071 13.0 0.3 0.39 10.6 0.3 1.9 1 1 0 1 1 1 0 PDZ domain G-alpha PF00503.20 KIK37052.1 - 9.8e-108 360.5 0.7 1.2e-107 360.2 0.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK37052.1 - 1.6e-12 47.2 0.1 1e-08 34.8 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KIK37052.1 - 0.00027 21.1 0.0 0.84 9.9 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KIK37052.1 - 0.0016 17.9 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein Zeta_toxin PF06414.12 KIK37052.1 - 0.01 15.1 1.9 0.012 14.9 0.1 2.0 2 1 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 KIK37052.1 - 0.025 14.9 0.0 0.051 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Na_H_Exchanger PF00999.21 KIK37053.1 - 1.4e-74 251.2 33.8 1.8e-74 250.9 33.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Tim17 PF02466.19 KIK37053.1 - 0.042 14.2 0.0 3.5 8.0 0.0 2.9 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Herpes_TK_C PF08465.10 KIK37053.1 - 0.8 9.5 2.6 0.41 10.4 0.1 1.8 2 0 0 2 2 2 0 Thymidine kinase from Herpesvirus C-terminal CPP1-like PF11833.8 KIK37053.1 - 5.1 6.7 5.8 1.8 8.2 0.2 2.6 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like 60KD_IMP PF02096.20 KIK37054.1 - 9.7e-17 61.4 7.2 1.2e-16 61.0 7.2 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein DUF202 PF02656.15 KIK37055.1 - 0.00034 21.0 6.9 0.00043 20.7 4.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) RTBV_P12 PF06361.11 KIK37056.1 - 0.061 13.7 0.1 0.19 12.2 0.1 2.0 1 0 0 1 1 1 0 Rice tungro bacilliform virus P12 protein EF1_GNE PF00736.19 KIK37059.1 - 3.8e-32 110.3 2.0 6.5e-32 109.6 2.0 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KIK37059.1 - 1e-11 45.0 9.5 1e-11 45.0 9.5 2.3 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_2 PF13410.6 KIK37059.1 - 0.015 15.3 0.0 0.038 14.0 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIK37059.1 - 0.016 15.4 0.7 0.41 10.9 0.0 2.5 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK37059.1 - 0.024 14.8 0.2 0.081 13.1 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain HTH_23 PF13384.6 KIK37060.1 - 9.3e-06 25.3 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.15 KIK37060.1 - 0.00018 21.5 0.0 0.28 11.3 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KIK37060.1 - 0.0007 20.2 0.0 0.43 11.2 0.0 2.1 1 1 1 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.6 KIK37060.1 - 0.0026 17.7 0.0 0.0034 17.4 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_AraC PF00165.23 KIK37060.1 - 0.0029 17.7 0.0 0.033 14.3 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_28 PF13518.6 KIK37060.1 - 0.005 16.9 0.0 0.007 16.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain UPF0175 PF03683.13 KIK37060.1 - 0.0078 15.9 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0175) HTH_Tnp_1_2 PF13022.6 KIK37060.1 - 0.085 13.0 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase DUF134 PF02001.16 KIK37060.1 - 0.17 12.5 0.0 0.25 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF134 CENP-B_N PF04218.13 KIK37060.1 - 0.18 11.5 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain WD40 PF00400.32 KIK37061.1 - 5.6e-22 77.6 20.7 1e-09 38.8 4.1 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37061.1 - 3.1e-15 56.2 3.0 0.0013 19.0 0.0 4.6 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK37061.1 - 3.6e-06 25.9 0.8 0.04 12.6 0.3 3.9 2 1 2 4 4 4 1 Nucleoporin Nup120/160 PQQ PF01011.21 KIK37061.1 - 8e-06 25.5 2.5 1.9 8.6 0.0 4.9 5 0 0 5 5 5 2 PQQ enzyme repeat eIF2A PF08662.11 KIK37061.1 - 0.0002 21.3 0.3 0.09 12.6 0.1 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK37061.1 - 0.0012 18.2 0.0 0.018 14.3 0.0 2.3 1 1 1 2 2 2 2 WD40-like domain Nbas_N PF15492.6 KIK37061.1 - 0.0013 18.1 1.6 4.1 6.6 0.0 3.8 1 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal SGL PF08450.12 KIK37061.1 - 0.0085 15.7 0.2 0.069 12.7 0.1 2.6 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Ge1_WD40 PF16529.5 KIK37061.1 - 0.033 13.2 0.0 6.1 5.7 0.0 2.6 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 KIK37061.1 - 0.075 13.6 0.7 1.5 9.4 0.3 3.1 3 1 0 3 3 3 0 PQQ-like domain Minor_capsid_3 PF12691.7 KIK37061.1 - 0.078 13.4 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage MerC PF03203.14 KIK37063.1 - 9 6.8 13.4 1.1e+03 0.1 13.5 2.7 1 1 0 1 1 1 0 MerC mercury resistance protein MFS_1 PF07690.16 KIK37064.1 - 5.1e-16 58.5 35.2 5.1e-16 58.5 35.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIK37064.1 - 1.9e-13 50.4 9.3 1.9e-13 50.4 9.3 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 FixQ PF05545.11 KIK37064.1 - 2.1 8.4 7.8 1.3 9.1 2.4 3.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ MFS_1 PF07690.16 KIK37065.1 - 3.2e-14 52.6 31.7 3.2e-14 52.6 31.7 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIK37065.1 - 9.2e-12 44.9 8.4 9.2e-12 44.9 8.4 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 UNC-93 PF05978.16 KIK37066.1 - 2.3e-12 46.9 9.9 4e-12 46.1 8.7 2.1 1 1 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KIK37066.1 - 7.6e-12 44.8 40.0 7.6e-12 44.8 40.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily p450 PF00067.22 KIK37069.1 - 1.1e-69 235.4 0.0 1.4e-69 235.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nab2p_Zf1 PF18260.1 KIK37070.1 - 0.12 12.4 0.5 0.21 11.5 0.5 1.4 1 0 0 1 1 1 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 Pet127 PF08634.10 KIK37074.1 - 9.8e-104 346.6 0.0 1.6e-103 345.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 GREB1 PF15782.5 KIK37074.1 - 0.18 8.9 2.0 0.3 8.1 2.0 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Arf PF00025.21 KIK37075.1 - 1.4e-40 138.6 0.0 1.7e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KIK37075.1 - 2.1e-17 63.2 0.0 2.4e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK37075.1 - 6.2e-14 52.2 0.0 8.9e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KIK37075.1 - 1e-08 34.8 0.0 1.2e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KIK37075.1 - 2.7e-07 30.2 0.0 3.2e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIK37075.1 - 7.2e-06 26.1 0.0 1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KIK37075.1 - 1.7e-05 24.2 0.5 0.00013 21.3 0.1 2.2 1 1 0 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.27 KIK37075.1 - 0.0086 15.6 0.0 0.014 14.9 0.0 1.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KIK37075.1 - 0.024 14.7 0.3 0.78 9.8 0.8 2.2 1 1 0 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 KIK37075.1 - 0.046 13.5 0.2 3.1 7.5 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein WD40 PF00400.32 KIK37077.1 - 9.5e-37 124.4 5.7 1.4e-05 25.7 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37077.1 - 8.4e-12 45.2 0.0 0.43 10.9 0.0 5.4 2 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK37077.1 - 3.3e-06 26.3 0.9 1.2 8.0 0.1 4.7 2 2 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KIK37077.1 - 0.00064 18.4 0.0 0.088 11.3 0.0 2.8 2 1 1 3 3 3 1 Cytochrome D1 heme domain PD40 PF07676.12 KIK37077.1 - 0.00066 19.5 0.1 8.6 6.4 0.0 5.0 4 1 1 5 5 5 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 KIK37077.1 - 0.014 15.0 0.5 0.081 12.5 0.3 2.1 1 1 0 2 2 2 0 PQQ-like domain Nup160 PF11715.8 KIK37077.1 - 0.014 14.0 0.2 0.12 11.0 0.0 2.5 4 0 0 4 4 4 0 Nucleoporin Nup120/160 Cupredoxin_1 PF13473.6 KIK37077.1 - 0.037 14.1 0.0 0.55 10.4 0.0 2.3 1 1 1 2 2 2 0 Cupredoxin-like domain PQQ PF01011.21 KIK37077.1 - 0.1 12.5 0.0 30 4.8 0.0 4.0 3 0 0 3 3 3 0 PQQ enzyme repeat PKHD_C PF18331.1 KIK37077.1 - 0.18 11.9 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 PKHD-type hydroxylase C-terminal domain PALB2_WD40 PF16756.5 KIK37077.1 - 0.23 10.3 0.6 1 8.2 0.1 2.2 2 2 2 4 4 4 0 Partner and localizer of BRCA2 WD40 domain WD40 PF00400.32 KIK37079.1 - 2.6e-39 132.5 3.5 1.7e-05 25.5 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37079.1 - 1.3e-11 44.6 0.3 0.063 13.6 0.0 6.0 1 1 6 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK37079.1 - 6.5e-06 25.3 0.2 0.46 9.4 0.0 4.4 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK37079.1 - 0.0025 17.7 0.2 22 5.1 0.0 5.2 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK37079.1 - 0.0046 15.7 0.1 0.11 11.1 0.0 2.8 2 1 0 3 3 3 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KIK37079.1 - 0.014 15.0 1.4 0.061 12.9 1.4 2.1 1 1 1 2 2 2 0 PQQ-like domain PALB2_WD40 PF16756.5 KIK37079.1 - 0.031 13.2 0.1 1.8 7.4 0.0 2.5 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain NuA4 PF09340.10 KIK37079.1 - 0.33 10.9 3.8 24 4.9 2.6 2.5 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 tRNA_Me_trans PF03054.16 KIK37081.1 - 3.6e-114 381.2 0.0 4.1e-114 381.1 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 KIK37081.1 - 0.007 15.5 0.0 3.2 6.8 0.0 2.4 2 0 0 2 2 2 2 NAD synthase Radical_SAM_C PF16199.5 KIK37082.1 - 4.1e-30 103.6 0.0 7.7e-30 102.8 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KIK37082.1 - 1.5e-17 64.5 0.1 6.1e-17 62.5 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KIK37082.1 - 6.9e-10 39.2 0.2 1.4e-09 38.2 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK37082.1 - 1.8e-06 27.9 0.0 5.3e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK37082.1 - 0.0022 18.4 0.1 0.0092 16.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK37082.1 - 0.042 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein p450 PF00067.22 KIK37083.1 - 8.5e-69 232.5 0.0 1e-68 232.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3048 PF11258.8 KIK37085.1 - 0.1 12.7 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) N-terminal domain MMM1 PF10296.9 KIK37086.1 - 5.2e-10 38.9 0.0 1.4e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 HOIP-UBA PF16678.5 KIK37087.1 - 0.0022 18.0 0.1 0.003 17.6 0.1 1.2 1 0 0 1 1 1 1 HOIP UBA domain pair Exonuc_VIII PF06630.11 KIK37087.1 - 0.098 12.5 0.0 0.098 12.5 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII Nuc_sug_transp PF04142.15 KIK37090.1 - 2.8e-90 302.7 11.6 1.7e-89 300.1 11.6 1.8 1 1 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 KIK37090.1 - 0.0013 18.2 4.2 0.0013 18.2 4.2 2.6 3 0 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.20 KIK37090.1 - 0.0075 16.4 6.8 0.0075 16.4 6.8 3.3 2 2 1 3 3 3 1 EamA-like transporter family UAA PF08449.11 KIK37090.1 - 0.03 13.5 12.5 0.09 12.0 12.4 1.8 1 1 0 1 1 1 0 UAA transporter family DUF3761 PF12587.8 KIK37091.1 - 0.066 13.6 0.1 3.7 8.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3761) Mit_ribos_Mrp51 PF11709.8 KIK37093.1 - 2.2e-18 67.0 1.5 4.4e-18 66.0 1.5 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit CENP-C_C PF11699.8 KIK37094.1 - 9.6e-28 96.2 0.1 1.7e-27 95.4 0.1 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 KIK37094.1 - 2.6e-07 30.2 0.0 5.7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KIK37094.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Cupin DUF1676 PF07898.13 KIK37094.1 - 0.9 9.6 3.5 1.8 8.6 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) CDC45 PF02724.14 KIK37094.1 - 7.4 4.7 12.0 11 4.2 12.0 1.2 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.32 KIK37098.1 - 3.8e-33 113.0 22.0 2.1e-07 31.5 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37098.1 - 8.1e-17 61.3 1.2 0.0038 17.5 0.0 4.8 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK37098.1 - 6.8e-06 25.3 0.0 1.4 7.8 0.0 4.1 2 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK37098.1 - 0.00033 19.4 0.3 0.042 12.5 0.1 3.3 4 1 0 4 4 4 1 Nucleoporin Nup120/160 Peptidase_C58 PF03543.14 KIK37099.1 - 0.32 10.7 8.7 0.027 14.2 3.9 1.7 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen DDHD PF02862.17 KIK37099.1 - 7.1 6.7 6.9 12 6.0 6.9 1.3 1 0 0 1 1 1 0 DDHD domain DUF1275 PF06912.11 KIK37105.1 - 3.9e-32 111.8 19.0 4.9e-32 111.4 19.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MFS_1 PF07690.16 KIK37105.1 - 1.1 8.1 21.3 0.28 10.0 11.6 2.3 2 1 0 2 2 2 0 Major Facilitator Superfamily DUF1275 PF06912.11 KIK37106.1 - 1.2e-29 103.6 16.5 1.5e-29 103.3 16.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) TauE PF01925.19 KIK37106.1 - 0.22 11.1 13.8 0.59 9.7 12.6 2.1 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE Kelch_3 PF13415.6 KIK37108.1 - 4.9e-32 109.6 10.0 2.8e-09 37.0 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KIK37108.1 - 2.1e-27 94.9 12.0 2.4e-07 30.6 0.1 6.6 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KIK37108.1 - 2.3e-20 72.1 10.5 1.4e-06 28.4 0.1 5.1 5 1 1 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KIK37108.1 - 2.6e-20 71.7 10.5 2.3e-06 27.1 0.1 5.6 5 1 0 5 5 5 4 Kelch motif DUF4110 PF13422.6 KIK37108.1 - 1.9e-17 63.1 0.3 1.9e-17 63.1 0.3 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_5 PF13854.6 KIK37108.1 - 1.1e-16 60.4 15.0 4.5e-06 26.5 0.1 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KIK37108.1 - 3.4e-13 49.0 12.9 0.0003 20.6 0.1 5.4 5 1 0 5 5 5 3 Kelch motif VIT1 PF01988.19 KIK37108.1 - 0.27 11.1 0.4 2.1 8.2 0.0 2.4 2 1 0 3 3 3 0 VIT family Gln-synt_C PF00120.24 KIK37109.1 - 1.2e-61 208.6 0.0 1.6e-61 208.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Flu_M2 PF00599.17 KIK37109.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Influenza Matrix protein (M2) Motilin_assoc PF04643.12 KIK37110.1 - 0.087 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide zf-C2H2 PF00096.26 KIK37112.1 - 7.3e-05 23.0 16.1 0.014 15.9 1.2 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK37112.1 - 0.0014 19.0 7.9 0.047 14.1 0.3 3.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK37112.1 - 0.0018 18.9 17.4 0.32 12.0 1.9 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KIK37112.1 - 0.009 16.3 1.0 0.016 15.5 1.0 1.4 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) DM PF00751.18 KIK37112.1 - 0.11 12.5 6.0 0.71 9.8 0.7 2.3 2 0 0 2 2 2 0 DM DNA binding domain zf-met PF12874.7 KIK37112.1 - 0.46 10.9 0.2 0.46 10.9 0.2 3.3 3 1 0 3 3 3 0 Zinc-finger of C2H2 type ATG101 PF07855.12 KIK37116.1 - 1.7e-40 138.5 0.4 1.9e-40 138.4 0.4 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 MAPEG PF01124.18 KIK37117.1 - 5.2e-19 68.4 0.7 6.4e-19 68.1 0.7 1.1 1 0 0 1 1 1 1 MAPEG family AAA_16 PF13191.6 KIK37120.1 - 2e-05 25.1 0.0 6e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KIK37120.1 - 0.017 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA12 PF10443.9 KIK37120.1 - 0.035 12.8 0.2 0.61 8.8 0.0 2.5 2 1 1 3 3 3 0 RNA12 protein COX4 PF02936.14 KIK37120.1 - 0.061 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV AAA_25 PF13481.6 KIK37120.1 - 0.071 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KIK37120.1 - 0.072 13.0 0.0 0.79 9.6 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 KIK37120.1 - 0.12 12.2 0.0 7.6 6.4 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase WD40 PF00400.32 KIK37121.1 - 2.3e-10 40.9 6.4 0.0014 19.5 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37121.1 - 0.0023 18.2 0.1 0.11 12.8 0.0 2.9 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain BCHF PF07284.11 KIK37121.1 - 6.9 6.7 9.0 6.5 6.8 6.4 2.1 2 0 0 2 2 2 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) Ribosomal_L21e PF01157.18 KIK37122.1 - 4.9e-44 148.3 5.3 4.9e-44 148.3 5.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e RNA_replicase_B PF03431.13 KIK37122.1 - 0.15 10.5 0.6 0.18 10.3 0.6 1.0 1 0 0 1 1 1 0 RNA replicase, beta-chain S4 PF01479.25 KIK37123.1 - 9.2e-11 41.3 1.0 9.2e-11 41.3 1.0 2.8 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KIK37123.1 - 3.2e-06 28.0 0.0 4.6e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L28e PF01778.17 KIK37125.1 - 1.6e-29 102.9 0.0 2.2e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family COX5A PF02284.16 KIK37126.1 - 4.4e-44 148.7 0.1 5.6e-44 148.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va SMC_N PF02463.19 KIK37127.1 - 6.7e-14 51.8 0.0 9.5e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIK37127.1 - 6.7e-07 29.4 0.0 8.1e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIK37127.1 - 1.2e-06 29.1 0.1 1.6e-06 28.8 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIK37127.1 - 1.2e-05 25.0 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KIK37127.1 - 2.8e-05 24.0 0.0 3.1e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KIK37127.1 - 0.028 14.9 0.0 0.041 14.4 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_27 PF13514.6 KIK37127.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2813 PF11398.8 KIK37127.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) SMC_ScpA PF02616.14 KIK37128.1 - 0.024 14.5 1.2 0.03 14.2 1.2 1.0 1 0 0 1 1 1 0 Segregation and condensation protein ScpA Seadorna_VP6 PF07407.11 KIK37128.1 - 0.072 12.0 0.6 0.086 11.8 0.6 1.0 1 0 0 1 1 1 0 Seadornavirus VP6 protein WD40 PF00400.32 KIK37129.1 - 1.9e-21 75.9 0.5 4.5e-10 39.9 0.1 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37129.1 - 6.1e-07 29.7 0.0 0.0073 16.6 0.0 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK37129.1 - 6.2e-07 28.7 0.0 0.007 15.4 0.0 2.0 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK37129.1 - 5.3e-05 23.0 0.4 0.39 10.7 0.0 2.6 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Ret2_MD PF18528.1 KIK37129.1 - 0.0071 16.7 0.0 1.3 9.4 0.0 2.2 2 0 0 2 2 2 1 RNA editing 3' terminal uridylyl transferase 2 middle domain Nup160 PF11715.8 KIK37129.1 - 0.06 12.0 0.1 2.4 6.7 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK37129.1 - 0.11 11.9 0.1 10 5.3 0.0 2.0 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal zf-CCHH PF10283.9 KIK37132.1 - 0.00016 21.6 3.0 0.00033 20.6 3.0 1.4 1 0 0 1 1 1 1 PBZ domain Nucleoporin_FG PF13634.6 KIK37133.1 - 1.3e-28 99.7 145.0 4.5e-09 37.0 23.8 3.6 1 1 3 4 4 4 4 Nucleoporin FG repeat region Nucleoporin_FG2 PF15967.5 KIK37134.1 - 2.6e-14 52.7 2.0 3.4e-14 52.3 2.0 1.0 1 0 0 1 1 1 1 Nucleoporin FG repeated region DUF1944 PF09175.10 KIK37134.1 - 0.0081 16.0 0.2 0.21 11.4 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1944) Occludin_ELL PF07303.13 KIK37134.1 - 0.036 14.8 5.0 14 6.4 0.1 3.6 2 2 2 4 4 4 0 Occludin homology domain AceK PF06315.11 KIK37134.1 - 0.079 11.4 2.9 0.047 12.2 1.3 1.4 2 0 0 2 2 2 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) GAS PF13851.6 KIK37134.1 - 0.13 11.6 6.0 0.55 9.5 5.4 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding KxDL PF10241.9 KIK37134.1 - 0.25 11.6 5.4 0.45 10.8 0.2 3.1 2 2 2 4 4 4 0 Uncharacterized conserved protein Tam41_Mmp37 PF09139.11 KIK37134.1 - 0.46 9.9 3.9 0.76 9.1 2.1 1.8 1 1 1 2 2 2 0 Phosphatidate cytidylyltransferase, mitochondrial V_ATPase_I PF01496.19 KIK37134.1 - 0.71 7.7 7.5 0.1 10.5 1.6 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF1690 PF07956.11 KIK37134.1 - 2.2 8.7 8.6 2 8.8 1.4 2.2 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) YebO PF13974.6 KIK37135.1 - 0.099 12.7 0.2 0.3 11.2 0.1 1.8 2 0 0 2 2 2 0 YebO-like protein Mitofilin PF09731.9 KIK37136.1 - 1.9e-110 370.6 15.0 2.6e-110 370.1 15.0 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF4854 PF16146.5 KIK37136.1 - 0.06 13.7 8.4 0.46 10.8 0.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4854) MbeB_N PF04837.12 KIK37136.1 - 1.4 9.3 8.6 4.2 7.7 1.4 3.5 3 0 0 3 3 3 0 MbeB-like, N-term conserved region MFS_1 PF07690.16 KIK37141.1 - 2.7e-34 118.6 43.3 2.7e-34 118.6 43.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1294 PF06961.13 KIK37141.1 - 0.082 13.2 0.2 0.46 10.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) Phage_holin_3_2 PF04550.12 KIK37141.1 - 0.1 13.1 4.7 1 9.9 1.5 2.8 2 0 0 2 2 2 0 Phage holin family 2 VanZ PF04892.12 KIK37141.1 - 0.17 12.6 4.9 0.32 11.7 0.3 3.1 3 1 0 3 3 3 0 VanZ like family Mannitol_dh PF01232.23 KIK37141.1 - 0.22 11.7 0.0 0.44 10.7 0.0 1.4 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain Arrestin_N PF00339.29 KIK37142.1 - 2e-09 37.7 0.0 6.8e-06 26.2 0.0 2.6 1 1 1 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Methyltransf_16 PF10294.9 KIK37143.1 - 1.1e-18 67.6 0.0 7.9e-18 64.8 0.0 1.9 1 1 0 1 1 1 1 Lysine methyltransferase DUF2475 PF10629.9 KIK37146.1 - 0.0024 18.1 1.7 0.013 15.7 1.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2475) Peptidase_C48 PF02902.19 KIK37148.1 - 6.5e-11 42.5 0.0 1.4e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain TRAF_BIRC3_bd PF16673.5 KIK37149.1 - 0.012 15.4 2.1 0.024 14.4 2.1 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain ABC_tran_CTD PF16326.5 KIK37149.1 - 0.19 12.0 1.5 0.54 10.5 1.5 1.8 1 0 0 1 1 1 0 ABC transporter C-terminal domain bZIP_1 PF00170.21 KIK37149.1 - 0.2 11.7 8.5 5.1 7.3 0.6 3.4 1 1 2 3 3 3 0 bZIP transcription factor TSC22 PF01166.18 KIK37149.1 - 0.25 11.7 4.8 10 6.5 0.1 3.3 1 1 2 3 3 3 0 TSC-22/dip/bun family Cupin_4 PF08007.12 KIK37150.1 - 9.6e-06 25.3 0.1 1.6e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 KIK37150.1 - 0.0016 18.2 0.2 0.003 17.3 0.2 1.4 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KIK37150.1 - 0.019 15.4 0.0 0.085 13.3 0.0 2.1 2 1 0 2 2 2 0 JmjC domain, hydroxylase Cupin_2 PF07883.11 KIK37150.1 - 0.053 13.2 0.0 0.37 10.5 0.0 2.2 2 0 0 2 2 2 0 Cupin domain DUF745 PF05335.13 KIK37157.1 - 0.13 12.0 3.6 4.1 7.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF1754 PF08555.10 KIK37157.1 - 6 7.7 11.7 7.2 7.5 11.7 1.3 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DUF3450 PF11932.8 KIK37159.1 - 0.091 12.1 0.7 0.17 11.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Flavin_Reduct PF01613.18 KIK37163.1 - 6.9e-20 71.7 0.9 1e-19 71.1 0.9 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Fe-ADH PF00465.19 KIK37165.1 - 2.3e-64 217.5 0.0 2.8e-64 217.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KIK37165.1 - 2e-12 47.4 0.1 1.4e-11 44.6 0.1 2.1 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Cation_efflux PF01545.21 KIK37166.1 - 2.7e-47 161.1 3.1 3.9e-47 160.6 3.1 1.3 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KIK37166.1 - 2.4e-07 30.8 0.1 5.1e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Dcc1 PF09724.9 KIK37167.1 - 3e-85 286.5 0.1 3.5e-85 286.2 0.1 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 DUF262 PF03235.14 KIK37168.1 - 2e-17 64.1 1.3 5.6e-17 62.7 1.2 1.5 1 1 0 1 1 1 1 Protein of unknown function DUF262 FbpA PF05833.11 KIK37168.1 - 0.0026 16.6 0.0 0.0042 15.9 0.0 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Mg_trans_NIPA PF05653.14 KIK37169.1 - 2.9e-17 62.7 12.6 4.1e-09 36.0 1.5 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KIK37169.1 - 0.0014 18.8 28.1 0.0033 17.6 9.4 3.3 3 1 0 3 3 3 2 EamA-like transporter family S-antigen PF05756.11 KIK37169.1 - 0.28 11.6 1.7 0.84 10.0 1.7 1.7 1 0 0 1 1 1 0 S-antigen protein DUF4834 PF16118.5 KIK37169.1 - 6 7.9 0.0 6 7.9 0.0 3.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4834) Tcp11 PF05794.13 KIK37170.1 - 3.5e-13 49.5 4.8 1.2e-11 44.4 4.8 2.4 1 1 0 1 1 1 1 T-complex protein 11 APAF1_C PF17908.1 KIK37170.1 - 0.099 12.6 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 APAF-1 helical domain p450 PF00067.22 KIK37172.1 - 1.9e-60 205.0 0.0 2.3e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 KIK37173.1 - 0.00059 20.6 0.0 0.00072 20.3 0.0 1.1 1 0 0 1 1 1 1 WD domain, G-beta repeat Ssl1 PF04056.14 KIK37174.1 - 2.6e-69 232.9 0.0 3.5e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 KIK37174.1 - 1.2e-13 51.0 10.1 1.2e-13 51.0 10.1 3.0 3 0 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.6 KIK37174.1 - 4.7e-12 46.5 0.0 9.5e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 KIK37174.1 - 0.0085 15.6 5.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 2 Transcription factor Tfb4 zf-HIT PF04438.16 KIK37174.1 - 0.09 12.7 0.5 0.09 12.7 0.5 3.4 4 0 0 4 4 4 0 HIT zinc finger zinc_ribbon_15 PF17032.5 KIK37174.1 - 2.4 9.0 17.5 0.09 13.5 8.3 2.8 1 1 1 2 2 2 0 zinc-ribbon family Dickkopf_N PF04706.12 KIK37175.1 - 0.018 15.5 6.4 0.018 15.5 6.4 4.9 5 0 0 5 5 5 0 Dickkopf N-terminal cysteine-rich region SCP1201-deam PF14428.6 KIK37177.1 - 0.055 13.3 0.4 0.23 11.3 0.5 1.8 1 1 1 2 2 2 0 SCP1.201-like deaminase PAAR_motif PF05488.13 KIK37177.1 - 0.19 11.9 0.7 0.28 11.4 0.7 1.2 1 0 0 1 1 1 0 PAAR motif Peptidase_M20 PF01546.28 KIK37179.1 - 0.015 15.0 0.0 0.017 14.9 0.0 1.0 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 CCDC92 PF14916.6 KIK37179.1 - 0.16 11.7 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain of unknown function zf-H2C2_2 PF13465.6 KIK37180.1 - 0.0067 16.8 0.5 0.02 15.3 0.5 1.9 1 0 0 1 1 1 1 Zinc-finger double domain zf-met PF12874.7 KIK37180.1 - 0.4 11.2 2.7 19 5.8 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type HCV_NS4b PF01001.19 KIK37181.1 - 0.032 13.8 0.1 0.041 13.5 0.1 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4b CdvA PF18822.1 KIK37183.1 - 0.054 13.3 1.5 4.4 7.1 0.1 3.0 1 1 2 3 3 3 0 CdvA-like coiled-coil domain DsrD PF08679.11 KIK37184.1 - 0.15 12.4 0.0 0.42 10.9 0.0 1.8 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) Cyclase PF04199.13 KIK37186.1 - 1.4e-34 119.3 0.6 1.6e-34 119.0 0.6 1.1 1 0 0 1 1 1 1 Putative cyclase nlz1 PF12402.8 KIK37186.1 - 0.12 12.8 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 NocA-like zinc-finger protein 1 Cyclase PF04199.13 KIK37187.1 - 1.6e-32 112.6 0.0 1.9e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase 3HCDH_N PF02737.18 KIK37188.1 - 3.2e-51 173.8 1.9 1.9e-50 171.3 1.9 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KIK37188.1 - 1.8e-31 108.6 0.0 4.2e-31 107.4 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 KIK37188.1 - 0.0065 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TetR_C_25 PF17933.1 KIK37188.1 - 0.018 15.3 0.0 0.055 13.8 0.1 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain 2-Hacid_dh_C PF02826.19 KIK37188.1 - 0.035 13.5 0.8 1.3 8.3 0.1 2.1 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KIK37188.1 - 0.078 13.1 0.5 0.25 11.5 0.5 1.8 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KIK37188.1 - 6.2 7.5 8.9 72 4.1 6.4 2.7 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent IIGP PF05049.13 KIK37189.1 - 4.1e-24 85.3 0.0 1.5e-23 83.5 0.0 1.9 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KIK37189.1 - 4.3e-05 23.6 0.0 0.00015 21.9 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KIK37189.1 - 0.011 16.0 0.0 0.044 14.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KIK37189.1 - 0.09 13.3 0.7 0.43 11.1 0.0 2.3 3 0 0 3 3 3 0 ABC transporter RsgA_GTPase PF03193.16 KIK37189.1 - 0.17 11.7 0.3 0.45 10.4 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase DUF4824 PF16106.5 KIK37189.1 - 0.25 10.6 16.5 0.085 12.1 12.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4824) V_ATPase_I PF01496.19 KIK37189.1 - 0.36 8.7 0.9 0.58 8.0 0.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Flagellin_N PF00669.20 KIK37189.1 - 0.43 10.7 4.7 1.1 9.4 4.7 1.6 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Spc7 PF08317.11 KIK37189.1 - 0.5 9.2 12.6 0.02 13.8 6.8 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_16 PF13191.6 KIK37189.1 - 0.58 10.5 0.0 0.58 10.5 0.0 2.8 2 1 0 2 2 1 0 AAA ATPase domain ISG65-75 PF11727.8 KIK37189.1 - 1.3 8.2 23.6 0.33 10.2 20.5 1.4 2 0 0 2 2 2 0 Invariant surface glycoprotein Dynamin_N PF00350.23 KIK37189.1 - 1.5 8.9 0.0 1.5 8.9 0.0 2.8 3 1 0 3 3 3 0 Dynamin family Borrelia_P83 PF05262.11 KIK37189.1 - 1.7 7.0 27.4 0.17 10.3 21.3 1.9 2 0 0 2 2 2 0 Borrelia P83/100 protein ERM PF00769.19 KIK37189.1 - 8.8 6.1 34.3 1.9 8.3 29.9 1.8 2 0 0 2 2 2 0 Ezrin/radixin/moesin family CAP_N PF01213.19 KIK37190.1 - 0.01 15.3 0.6 0.01 15.3 0.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 KIK37190.1 - 0.22 11.6 1.8 0.26 11.4 1.8 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CHAT PF12770.7 KIK37191.1 - 2.3e-31 109.3 0.0 5.2e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK37191.1 - 3.7e-07 29.8 25.0 0.003 17.4 0.9 7.3 8 1 1 9 9 8 3 Tetratricopeptide repeat MIT PF04212.18 KIK37191.1 - 6.8e-05 22.9 1.1 4.8 7.3 0.0 4.7 5 0 0 5 5 5 1 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 KIK37191.1 - 0.0014 18.9 21.4 0.31 11.3 0.8 7.1 6 1 2 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIK37191.1 - 0.0028 18.3 13.1 70 4.6 0.0 8.7 9 1 1 10 10 9 0 Tetratricopeptide repeat DUF2019 PF09450.10 KIK37191.1 - 0.018 14.9 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) TPR_7 PF13176.6 KIK37191.1 - 0.083 13.0 7.4 34 4.8 0.0 6.2 5 1 0 5 5 5 0 Tetratricopeptide repeat Cytokin_check_N PF10407.9 KIK37191.1 - 0.12 12.3 0.3 9.2 6.3 0.1 2.7 1 1 1 2 2 2 0 Cdc14 phosphatase binding protein N-terminus Dehydratase_SU PF02287.15 KIK37191.1 - 0.14 12.2 0.1 24 5.0 0.0 3.3 3 0 0 3 3 3 0 Dehydratase small subunit TPR_1 PF00515.28 KIK37191.1 - 0.15 11.9 6.8 38 4.3 0.8 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat PilJ PF13675.6 KIK37191.1 - 0.21 11.6 2.6 1.1 9.3 0.1 3.0 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Vta1_C PF18097.1 KIK37191.1 - 0.54 10.0 9.7 2.8 7.7 0.0 4.4 4 0 0 4 4 4 0 Vta1 C-terminal domain TPR_11 PF13414.6 KIK37191.1 - 0.63 9.8 1.8 12 5.7 0.5 3.6 4 0 0 4 4 4 0 TPR repeat GMC_oxred_N PF00732.19 KIK37192.1 - 7.3e-65 219.3 0.0 9.3e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK37192.1 - 1.1e-39 136.3 0.9 1.5e-39 135.8 0.1 1.7 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK37192.1 - 8.7e-06 25.0 0.1 1.3e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KIK37192.1 - 4.5e-05 23.6 0.0 0.00014 22.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIK37192.1 - 0.00019 20.7 0.0 0.00037 19.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KIK37192.1 - 0.00035 20.3 0.0 0.00074 19.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK37192.1 - 0.001 18.2 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK37192.1 - 0.0098 15.2 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK37192.1 - 0.064 12.0 0.0 0.096 11.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 KIK37192.1 - 0.065 12.1 0.0 0.092 11.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NmrA PF05368.13 KIK37196.1 - 1.7e-09 37.6 0.1 2.6e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK37196.1 - 4.5e-09 36.5 0.1 6.5e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIK37196.1 - 2.4e-07 30.5 0.1 0.0013 18.2 0.0 2.5 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK37196.1 - 1e-05 24.7 0.1 2.5e-05 23.4 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KIK37196.1 - 0.00019 21.9 0.0 0.00041 20.8 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KIK37196.1 - 0.0013 17.9 0.0 0.0035 16.5 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein Shikimate_DH PF01488.20 KIK37196.1 - 0.0059 16.7 0.0 0.0095 16.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KIK37196.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 KIK37196.1 - 0.053 14.1 0.0 0.15 12.6 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.23 KIK37196.1 - 0.071 13.2 0.4 0.38 10.8 0.1 2.0 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain KR PF08659.10 KIK37196.1 - 0.14 12.1 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 KR domain DUF641 PF04859.12 KIK37197.1 - 0.056 13.8 0.2 0.071 13.4 0.2 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF4442 PF14539.6 KIK37197.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) HET PF06985.11 KIK37199.1 - 7.8e-14 52.2 4.1 8.5e-12 45.6 0.3 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) WD40 PF00400.32 KIK37200.1 - 2.5e-25 88.2 20.4 1.3e-05 25.9 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37200.1 - 2.6e-07 30.9 1.0 1.7 9.0 0.0 5.1 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK37200.1 - 0.00074 18.6 0.1 1.6 7.6 0.0 4.0 4 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein MFS_1 PF07690.16 KIK37204.1 - 1.5e-30 106.4 42.5 1.5e-30 106.4 42.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK37204.1 - 2.5e-07 29.9 12.3 2.5e-07 29.9 12.3 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter CPP1-like PF11833.8 KIK37204.1 - 4.9 6.7 8.4 18 4.9 2.1 2.7 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF2583 PF10762.9 KIK37204.1 - 8.4 6.9 7.3 2.4 8.6 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) DUF1118 PF06549.12 KIK37207.1 - 0.026 14.8 1.5 0.033 14.5 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1118) MFS_1 PF07690.16 KIK37208.1 - 9.8e-29 100.4 29.7 1.3e-28 100.0 29.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK37208.1 - 6.1e-07 28.7 12.7 8.8e-07 28.1 12.7 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Cnn_1N PF07989.11 KIK37209.1 - 1.6e-23 82.7 9.7 1.6e-23 82.7 9.7 13.1 6 2 9 16 16 16 1 Centrosomin N-terminal motif 1 DUF5082 PF16888.5 KIK37209.1 - 0.005 17.1 2.4 0.005 17.1 2.4 9.5 3 3 4 7 7 7 1 Domain of unknown function (DUF5082) Mto2_bdg PF12808.7 KIK37209.1 - 0.0053 17.0 10.7 0.0053 17.0 10.7 10.8 12 0 0 12 12 12 3 Micro-tubular organiser Mto1 C-term Mto2-binding region SNCAIP_SNCA_bd PF16700.5 KIK37209.1 - 0.32 10.7 4.7 6.2 6.6 3.7 3.0 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain Glutaredoxin PF00462.24 KIK37210.1 - 7.6e-16 58.1 0.0 1.8e-15 56.9 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin LacI PF00356.21 KIK37210.1 - 0.081 12.7 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family FAD_binding_3 PF01494.19 KIK37211.1 - 4e-55 187.5 0.0 5.4e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Nsp3_PL2pro PF12124.8 KIK37213.1 - 0.035 13.9 0.1 0.054 13.3 0.1 1.3 1 0 0 1 1 1 0 Coronavirus polyprotein cleavage domain Fn3-like PF14310.6 KIK37217.1 - 1.4e-16 60.4 0.0 1.7e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Fibronectin type III-like domain p450 PF00067.22 KIK37218.1 - 1.8e-67 228.1 0.0 2.4e-67 227.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 tRNA-synt_1 PF00133.22 KIK37219.1 - 5.9e-37 127.2 0.0 5.9e-27 94.2 0.0 3.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KIK37219.1 - 4.7e-14 52.0 0.0 2.2e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KIK37219.1 - 1.2e-13 51.3 0.1 2.5e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KIK37219.1 - 1.4e-05 24.6 0.0 3.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain HSP70 PF00012.20 KIK37220.1 - 1.4e-261 869.0 6.4 1.6e-261 868.8 6.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIK37220.1 - 8.1e-20 70.9 3.8 1.4e-19 70.1 0.6 2.3 2 1 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 KIK37220.1 - 0.001 18.1 1.0 0.012 14.6 1.0 2.1 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain FIVAR PF07554.13 KIK37220.1 - 0.016 16.0 0.8 3.1 8.6 0.1 2.9 2 1 0 2 2 2 0 FIVAR domain Hydantoinase_A PF01968.18 KIK37220.1 - 0.041 13.1 0.1 0.14 11.4 0.1 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase DUF357 PF04010.13 KIK37220.1 - 0.14 12.3 0.1 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF357) Spectrin PF00435.21 KIK37220.1 - 1.4 9.4 7.3 11 6.6 0.3 3.5 3 1 0 3 3 3 0 Spectrin repeat CTP_transf_like PF01467.26 KIK37221.1 - 1.5e-22 80.3 0.0 2.4e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like SapA PF02199.15 KIK37221.1 - 0.039 14.3 0.6 0.067 13.5 0.6 1.3 1 0 0 1 1 1 0 Saposin A-type domain Amidohydro_3 PF07969.11 KIK37222.1 - 3.9e-79 267.3 0.0 6.5e-79 266.6 0.0 1.3 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_1 PF01979.20 KIK37222.1 - 1.1e-07 31.5 0.4 0.0001 21.8 0.0 2.9 2 1 0 2 2 2 2 Amidohydrolase family DSPc PF00782.20 KIK37223.1 - 1.8e-25 89.3 0.0 2.8e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 KIK37223.1 - 3.2e-06 27.6 0.0 1.5e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase2 PF03162.13 KIK37223.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 KIK37223.1 - 0.2 11.2 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CUE PF02845.16 KIK37226.1 - 3.3e-08 33.1 0.0 5.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 CUE domain HEPN_SAV_6107 PF18726.1 KIK37227.1 - 0.016 15.7 0.5 0.078 13.5 0.4 2.1 2 0 0 2 2 2 0 SAV_6107-like HEPN KDZ PF18758.1 KIK37228.1 - 1.1e-12 48.1 0.3 1.2e-12 48.0 0.3 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Hydrophobin PF01185.18 KIK37230.1 - 4.1e-18 65.8 9.4 4.8e-18 65.6 9.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KIK37233.1 - 3.7e-17 62.7 11.5 4.3e-17 62.5 11.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin ketoacyl-synt PF00109.26 KIK37237.1 - 5.1e-78 262.1 0.1 1.1e-77 261.1 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIK37237.1 - 2.7e-46 158.5 0.0 1.7e-44 152.7 0.0 2.4 2 0 0 2 2 2 1 Acyl transferase domain PP-binding PF00550.25 KIK37237.1 - 1.5e-42 143.8 16.1 9.6e-14 51.5 1.2 3.6 3 0 0 3 3 3 3 Phosphopantetheine attachment site Ketoacyl-synt_C PF02801.22 KIK37237.1 - 1.9e-34 118.2 0.3 5.2e-34 116.8 0.3 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain SAT PF16073.5 KIK37237.1 - 2.5e-28 99.5 5.5 5.5e-26 91.8 0.3 3.3 2 1 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis PS-DH PF14765.6 KIK37237.1 - 2.1e-23 83.0 0.8 4.4e-23 82.0 0.1 1.9 2 0 0 2 2 2 1 Polyketide synthase dehydratase Thioesterase PF00975.20 KIK37237.1 - 1.3e-13 51.6 0.0 3.5e-12 46.9 0.0 2.9 3 0 0 3 3 3 1 Thioesterase domain Thiolase_N PF00108.23 KIK37237.1 - 3.1e-06 26.7 0.6 7.6e-06 25.5 0.6 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 KIK37237.1 - 1.1e-05 26.2 9.3 0.00017 22.2 0.1 3.1 2 1 1 3 3 3 2 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 KIK37237.1 - 1.5e-05 25.4 0.0 5.6e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension DUF2974 PF11187.8 KIK37237.1 - 0.0026 17.3 0.0 0.0063 16.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 KIK37237.1 - 0.019 14.8 0.1 0.053 13.3 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KIK37237.1 - 0.04 13.8 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Kinesin PF00225.23 KIK37238.1 - 2.4e-91 306.1 0.0 4.5e-91 305.2 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KIK37238.1 - 8.6e-21 74.4 0.0 1.7e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Pox_A_type_inc PF04508.12 KIK37238.1 - 0.015 15.1 1.9 0.068 13.0 1.9 2.2 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat GFA PF04828.14 KIK37239.1 - 7.3e-08 32.6 1.1 1.1e-07 32.1 0.1 1.9 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Peptidase_S10 PF00450.22 KIK37241.1 - 1.3e-108 364.1 0.1 1.6e-108 363.8 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Mito_carr PF00153.27 KIK37242.1 - 3.8e-27 94.0 4.0 2.4e-14 53.0 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 KIK37244.1 - 3.4e-27 94.2 9.8 5.7e-05 23.8 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37244.1 - 1.4e-13 50.9 0.4 0.014 15.7 0.1 4.7 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KIK37244.1 - 0.018 14.4 0.2 6.4 6.0 0.0 2.9 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 KIK37244.1 - 0.031 14.1 0.0 0.21 11.5 0.0 2.0 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KIK37244.1 - 0.069 11.1 0.4 2.9 5.8 0.2 2.7 2 1 1 3 3 3 0 IKI3 family Ge1_WD40 PF16529.5 KIK37244.1 - 0.17 10.8 0.2 1.6 7.6 0.0 2.6 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK37244.1 - 0.24 11.4 7.1 1.4 8.9 0.0 4.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat bZIP_2 PF07716.15 KIK37246.1 - 2.9e-10 40.1 9.4 2.9e-10 40.1 9.4 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KIK37246.1 - 1.2e-08 34.9 8.7 1.2e-08 34.9 8.7 2.4 2 1 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 KIK37246.1 - 0.0031 18.0 3.8 0.0031 18.0 3.8 2.2 2 0 0 2 2 2 1 bZIP Maf transcription factor KIAA1430 PF13879.6 KIK37246.1 - 0.14 12.9 6.7 0.43 11.4 6.8 1.7 1 1 0 1 1 1 0 KIAA1430 homologue DUF5384 PF17358.2 KIK37246.1 - 9.6 6.2 14.9 1.9 8.5 6.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5384) FAD_binding_2 PF00890.24 KIK37247.1 - 2.5e-124 415.5 3.6 3.1e-124 415.2 3.6 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KIK37247.1 - 9.5e-44 148.5 0.7 1.4e-43 147.9 0.7 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 KIK37247.1 - 1.4e-06 27.6 4.2 0.0013 17.9 2.0 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KIK37247.1 - 2.7e-06 26.8 0.3 0.0013 18.0 0.1 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK37247.1 - 1.3e-05 24.6 0.1 0.0077 15.5 0.1 2.9 3 0 0 3 3 3 2 Thi4 family FAD_binding_3 PF01494.19 KIK37247.1 - 0.00076 18.8 0.2 0.0013 18.1 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIK37247.1 - 0.0037 16.9 0.7 0.012 15.2 0.7 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase TAL_FSA PF00923.19 KIK37247.1 - 0.0099 15.2 0.2 0.0099 15.2 0.2 1.5 2 0 0 2 2 2 1 Transaldolase/Fructose-6-phosphate aldolase Lycopene_cycl PF05834.12 KIK37247.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 KIK37247.1 - 0.019 13.7 1.8 0.12 11.0 0.8 2.5 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.6 KIK37247.1 - 0.27 10.5 4.5 0.26 10.5 1.3 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.7 KIK37248.1 - 1.4e-06 28.1 0.1 4.1e-05 23.4 0.0 3.1 2 1 0 2 2 2 1 F-box-like YjcZ PF13990.6 KIK37248.1 - 0.059 12.7 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 YjcZ-like protein Fungal_trans PF04082.18 KIK37250.1 - 1e-07 31.3 0.1 2.1e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK37250.1 - 1.9e-07 31.1 11.9 3.3e-07 30.3 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain W2 PF02020.18 KIK37251.1 - 1.5e-19 69.9 0.7 6.5e-19 67.9 0.1 2.4 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon PP2C PF00481.21 KIK37252.1 - 3.4e-62 210.4 0.2 5.4e-50 170.4 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KIK37252.1 - 0.00076 19.4 0.8 0.0045 16.9 0.4 2.4 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Ecl1 PF12855.7 KIK37252.1 - 0.0088 17.2 8.9 0.014 16.6 8.9 1.3 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins LIF_OSM PF01291.17 KIK37253.1 - 0.081 13.1 0.1 0.22 11.7 0.0 1.7 2 0 0 2 2 2 0 LIF / OSM family CHZ PF09649.10 KIK37256.1 - 7.5e-11 41.3 0.8 7.5e-11 41.3 0.8 3.3 3 1 0 3 3 3 1 Histone chaperone domain CHZ DNA_pol_phi PF04931.13 KIK37256.1 - 0.29 9.2 28.7 0.3 9.1 28.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 KIK37256.1 - 1.6 8.0 24.8 1.8 7.8 24.8 1.0 1 0 0 1 1 1 0 BUD22 TMEM119 PF15724.5 KIK37256.1 - 3 7.9 7.1 3.2 7.7 7.1 1.1 1 0 0 1 1 1 0 TMEM119 family Polysacc_deac_1 PF01522.21 KIK37260.1 - 7.9e-06 25.8 0.1 2.3e-05 24.3 0.1 1.8 1 1 0 1 1 1 1 Polysaccharide deacetylase Methyltransf_16 PF10294.9 KIK37263.1 - 1.3e-16 60.8 0.0 2.4e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 KIK37263.1 - 1.1e-07 32.5 0.0 2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK37263.1 - 1.4e-07 32.1 0.0 2.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK37263.1 - 7e-06 25.9 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK37263.1 - 7.2e-06 25.7 0.0 1.5e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KIK37263.1 - 3.4e-05 23.4 0.0 5.2e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KIK37263.1 - 0.00032 20.6 0.0 0.00067 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK37263.1 - 0.00063 20.3 0.0 0.0015 19.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIK37263.1 - 0.013 15.3 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 KIK37263.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein COesterase PF00135.28 KIK37264.1 - 6.5e-79 266.1 0.8 1.3e-78 265.1 0.8 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK37264.1 - 6.5e-06 26.2 3.0 4.8e-05 23.3 1.2 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK37264.1 - 0.017 15.7 0.5 0.13 12.9 0.1 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KIK37264.1 - 0.026 14.0 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2243 PF10002.9 KIK37264.1 - 0.044 13.9 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2243) DIOX_N PF14226.6 KIK37266.1 - 1.3e-13 51.8 0.0 3e-13 50.6 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK37266.1 - 2.9e-12 46.9 0.0 6e-12 45.9 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TIP49 PF06068.13 KIK37269.1 - 3.9e-157 522.9 1.0 5.4e-157 522.5 1.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KIK37269.1 - 1.9e-20 72.7 0.3 1.2e-19 70.2 0.5 2.2 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 KIK37269.1 - 1.9e-09 38.0 0.2 1.2e-05 25.8 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KIK37269.1 - 3.9e-07 29.9 0.2 0.00061 19.6 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 KIK37269.1 - 2.8e-06 26.9 0.5 6.1e-06 25.7 0.5 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KIK37269.1 - 0.00011 22.6 0.1 0.0006 20.2 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK37269.1 - 0.0027 18.0 0.3 0.33 11.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 KIK37269.1 - 0.003 17.2 0.6 0.011 15.3 0.6 2.1 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KIK37269.1 - 0.0031 16.9 3.6 0.054 12.9 0.4 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KIK37269.1 - 0.02 14.9 1.7 9.3 6.2 0.0 3.5 3 1 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIK37269.1 - 0.039 14.1 0.2 0.5 10.5 0.0 2.8 3 1 0 3 3 3 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 KIK37269.1 - 0.085 13.1 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK37269.1 - 0.13 11.7 0.1 0.7 9.4 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_19 PF13245.6 KIK37269.1 - 0.15 12.4 6.3 0.76 10.1 1.8 3.3 2 1 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KIK37269.1 - 0.2 10.7 0.3 0.39 9.8 0.0 1.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Ribosomal_L2_C PF03947.18 KIK37270.1 - 2.4e-53 179.7 1.6 6e-53 178.4 1.6 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KIK37270.1 - 1.2e-24 86.1 0.3 2.6e-24 85.0 0.3 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Homeodomain PF00046.29 KIK37271.1 - 4.9e-17 61.5 4.9 2.3e-16 59.3 5.2 2.0 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KIK37271.1 - 5.2e-05 23.1 0.1 0.00021 21.1 0.1 2.1 1 1 1 2 2 2 1 Homeobox KN domain Tudor_FRX1 PF18336.1 KIK37271.1 - 0.12 12.3 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Fragile X mental retardation Tudor domain adh_short PF00106.25 KIK37272.1 - 2.7e-40 137.9 0.0 3.2e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK37272.1 - 2.6e-33 115.6 0.1 3e-33 115.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK37272.1 - 2.4e-13 50.4 0.3 5.2e-13 49.3 0.3 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK37272.1 - 0.00074 19.1 0.0 0.0012 18.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK37272.1 - 0.0091 15.9 0.2 0.025 14.5 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KIK37272.1 - 0.056 13.7 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Eno-Rase_NADH_b PF12242.8 KIK37272.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.15 KIK37272.1 - 0.18 10.9 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SKI PF01202.22 KIK37274.1 - 0.019 15.1 2.0 0.28 11.3 0.0 2.8 3 0 0 3 3 3 0 Shikimate kinase zf-TFIIB PF13453.6 KIK37275.1 - 0.089 12.1 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Transcription factor zinc-finger Pkinase_fungal PF17667.1 KIK37281.1 - 0.00088 18.2 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Cauli_VI PF01693.16 KIK37283.1 - 0.036 14.4 0.0 0.048 14.0 0.0 1.3 1 0 0 1 1 1 0 Caulimovirus viroplasmin Hat1_N PF10394.9 KIK37284.1 - 4.4e-56 189.5 0.0 9.1e-56 188.5 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 KIK37284.1 - 9.7e-06 25.8 0.0 3.1e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 KIK37284.1 - 1.6e-05 24.6 0.3 3.2e-05 23.7 0.3 1.4 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_10 PF13673.7 KIK37284.1 - 0.0081 16.1 0.0 0.025 14.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK37284.1 - 0.01 16.2 0.0 0.029 14.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sterol-sensing PF12349.8 KIK37285.1 - 3.4e-35 121.1 6.8 8.6e-35 119.8 6.8 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KIK37285.1 - 9.9e-10 37.2 5.8 1.4e-09 36.6 5.8 1.1 1 0 0 1 1 1 1 Patched family Aldedh PF00171.22 KIK37286.1 - 1.7e-116 389.5 0.0 2.1e-116 389.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ProRS-C_1 PF09180.11 KIK37287.1 - 0.03 14.5 1.7 1 9.6 0.3 2.9 1 1 1 2 2 2 0 Prolyl-tRNA synthetase, C-terminal zf-CCHC PF00098.23 KIK37287.1 - 0.042 13.9 0.6 0.042 13.9 0.6 2.1 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 KIK37287.1 - 0.047 13.4 0.8 0.15 11.8 0.8 1.9 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 KIK37287.1 - 1.2 8.9 6.2 0.29 10.9 0.3 2.5 2 0 0 2 2 2 0 Zinc knuckle Phage_int_SAM_1 PF02899.17 KIK37288.1 - 0.037 14.3 0.0 0.076 13.3 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain SMI1_KNR4 PF09346.10 KIK37289.1 - 4.5e-23 82.1 0.0 8e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) CoA_trans PF01144.23 KIK37290.1 - 3.7e-100 333.8 2.0 1.2e-50 171.9 0.0 3.0 3 0 0 3 3 3 3 Coenzyme A transferase Mal_decarbox_Al PF16957.5 KIK37290.1 - 0.00029 19.3 0.2 0.0011 17.5 0.1 1.8 1 1 1 2 2 2 1 Malonate decarboxylase, alpha subunit, transporter AcetylCoA_hyd_C PF13336.6 KIK37290.1 - 0.0011 18.9 0.1 0.0021 18.0 0.1 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain BOFC_N PF08977.10 KIK37290.1 - 0.17 11.9 0.1 0.35 10.9 0.1 1.4 1 0 0 1 1 1 0 Bypass of Forespore C, N terminal CoA_trans PF01144.23 KIK37291.1 - 6.4e-102 339.5 0.7 1.5e-59 201.0 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KIK37291.1 - 0.0006 19.8 0.1 0.0017 18.3 0.0 1.7 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 KIK37291.1 - 0.1 12.6 0.0 0.71 9.8 0.0 2.3 3 0 0 3 3 3 0 Acetyl-CoA hydrolase/transferase N-terminal domain Peptidase_M23 PF01551.22 KIK37291.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M23 WD40 PF00400.32 KIK37294.1 - 2e-14 53.7 7.2 0.0002 22.1 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat PI3_PI4_kinase PF00454.27 KIK37296.1 - 3.5e-54 184.2 0.0 6.5e-54 183.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KIK37296.1 - 1.8e-33 116.2 0.4 3.7e-33 115.2 0.4 1.6 1 0 0 1 1 1 1 FAT domain UME PF08064.13 KIK37296.1 - 2.6e-28 97.9 0.0 2.5e-27 94.8 0.0 2.7 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.20 KIK37296.1 - 8.5e-10 38.3 0.1 8.5e-10 38.3 0.1 2.2 3 0 0 3 3 3 1 FATC domain DUF3385 PF11865.8 KIK37296.1 - 3.5e-05 23.8 0.0 0.0011 19.0 0.0 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) HEAT_EZ PF13513.6 KIK37296.1 - 0.00017 22.0 0.0 0.0017 18.8 0.0 3.0 1 0 0 1 1 1 1 HEAT-like repeat HEAT PF02985.22 KIK37296.1 - 0.0096 16.1 0.8 13 6.4 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat COX7a PF02238.15 KIK37297.1 - 7.4e-21 74.3 1.8 8.5e-21 74.1 1.8 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII YEATS PF03366.16 KIK37298.1 - 6.7e-38 128.5 0.0 1.1e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 YEATS family Spc7_N PF15402.6 KIK37298.1 - 0.078 11.2 0.1 0.1 10.8 0.1 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 M16C_assoc PF08367.11 KIK37298.1 - 0.56 9.3 3.0 0.77 8.8 3.0 1.1 1 0 0 1 1 1 0 Peptidase M16C associated UPF0029 PF01205.19 KIK37299.1 - 3.4e-31 107.7 0.0 5.8e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KIK37299.1 - 2.1e-05 24.8 0.0 4.4e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 RWD domain Zn_clus PF00172.18 KIK37301.1 - 1.3e-05 25.2 6.1 1.3e-05 25.2 6.1 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4598 PF15370.6 KIK37302.1 - 2.4e-10 40.9 0.3 2.4e-10 40.9 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) XPC-binding PF09280.11 KIK37302.1 - 0.045 13.5 0.7 0.71 9.6 0.1 2.4 2 0 0 2 2 2 0 XPC-binding domain Laminin_I PF06008.14 KIK37302.1 - 0.075 12.7 1.3 0.15 11.7 0.2 2.0 2 1 1 3 3 3 0 Laminin Domain I Apolipoprotein PF01442.18 KIK37302.1 - 0.081 12.8 1.1 0.1 12.4 0.2 1.6 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Atg29_N PF18388.1 KIK37303.1 - 1.8e-15 56.5 0.1 3.3e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 Atg29 N-terminal domain BUD22 PF09073.10 KIK37303.1 - 0.054 12.8 6.7 0.097 12.0 6.7 1.3 1 0 0 1 1 1 0 BUD22 Asp_protease PF09668.10 KIK37304.1 - 0.00013 21.8 0.1 0.00022 21.0 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease XPC-binding PF09280.11 KIK37304.1 - 0.004 16.9 3.8 0.015 15.0 2.3 2.1 2 0 0 2 2 2 1 XPC-binding domain UBA_4 PF14555.6 KIK37305.1 - 0.00026 20.7 0.0 0.00047 19.9 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.31 KIK37305.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 UBA/TS-N domain TFIID-18kDa PF02269.16 KIK37306.1 - 9.5e-32 108.9 0.1 2e-31 107.8 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIIE-A_C PF11521.8 KIK37306.1 - 0.0071 16.6 1.8 0.0071 16.6 1.8 2.5 2 0 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha MutS_II PF05188.17 KIK37306.1 - 0.086 13.1 0.5 0.17 12.1 0.0 1.7 2 0 0 2 2 2 0 MutS domain II PAPS_reduct PF01507.19 KIK37307.1 - 4.9e-42 143.9 0.0 6.3e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ComFB PF10719.9 KIK37307.1 - 0.021 14.9 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 Late competence development protein ComFB Ribonucleas_3_3 PF14622.6 KIK37308.1 - 4.3e-14 52.8 0.0 6.3e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KIK37308.1 - 9.1e-12 45.5 0.0 3.2e-11 43.8 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 KIK37308.1 - 4.6e-08 33.7 0.0 8e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Coiled-coil_56 PF09813.9 KIK37309.1 - 1.5e-05 25.0 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 zf-C2H2 PF00096.26 KIK37311.1 - 0.0028 18.0 8.2 0.037 14.5 1.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KIK37311.1 - 0.0055 16.9 6.8 0.64 10.1 0.1 2.8 3 0 0 3 3 3 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 KIK37311.1 - 0.21 12.5 14.0 1.6 9.8 0.7 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger EamA PF00892.20 KIK37312.1 - 6.5e-26 91.1 33.7 1.3e-15 57.8 8.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF3989 PF13150.6 KIK37312.1 - 0.11 12.2 0.0 0.61 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) TPT PF03151.16 KIK37312.1 - 0.96 8.7 16.9 2.9 7.1 1.9 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF2070 PF09843.9 KIK37312.1 - 1.3 7.2 21.2 0.38 9.0 9.3 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) EamA PF00892.20 KIK37314.1 - 1.1e-21 77.5 35.0 7.8e-13 48.8 10.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 KIK37314.1 - 0.0058 16.2 8.8 0.0098 15.4 8.8 1.3 1 0 0 1 1 1 1 Solute carrier family 35 TPT PF03151.16 KIK37314.1 - 0.32 10.3 17.6 1.1 8.6 4.1 2.1 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF2070 PF09843.9 KIK37314.1 - 4.7 5.4 25.8 0.015 13.6 9.9 2.0 1 1 0 2 2 2 0 Predicted membrane protein (DUF2070) EamA PF00892.20 KIK37316.1 - 3.2e-26 92.1 28.8 1e-14 54.9 7.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family Sugar_transport PF06800.12 KIK37316.1 - 0.00061 19.2 2.5 0.00061 19.2 2.5 2.4 2 1 0 2 2 2 2 Sugar transport protein DUF2070 PF09843.9 KIK37316.1 - 4 5.6 22.8 1.8 6.8 8.9 2.1 1 1 0 2 2 2 0 Predicted membrane protein (DUF2070) DUF3433 PF11915.8 KIK37318.1 - 8.8e-18 64.6 6.1 2.9e-17 62.9 6.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) SLATT_6 PF18169.1 KIK37318.1 - 0.029 14.0 0.1 0.029 14.0 0.1 1.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 Tubulin PF00091.25 KIK37319.1 - 2e-68 230.5 0.0 4.5e-68 229.4 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KIK37319.1 - 2.9e-42 143.8 0.1 4.7e-42 143.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KIK37319.1 - 4.4e-06 27.0 0.1 1.6e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KIK37319.1 - 0.0034 16.6 0.0 0.03 13.5 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 KIK37319.1 - 0.03 14.0 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain Macoilin PF09726.9 KIK37320.1 - 4.2 5.8 7.6 5.7 5.4 7.6 1.1 1 0 0 1 1 1 0 Macoilin family Cerato-platanin PF07249.12 KIK37324.1 - 5.2e-44 149.2 2.6 6.1e-44 148.9 2.6 1.0 1 0 0 1 1 1 1 Cerato-platanin adh_short PF00106.25 KIK37325.1 - 5.7e-48 163.0 1.4 6.4e-48 162.8 1.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK37325.1 - 3.3e-41 141.4 1.6 4e-41 141.1 1.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK37325.1 - 3e-09 37.1 0.9 8.8e-09 35.5 0.4 1.8 1 1 1 2 2 2 1 KR domain AAA PF00004.29 KIK37326.1 - 5.3e-49 166.0 0.1 6.5e-14 52.5 0.0 6.0 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 KIK37326.1 - 1.4e-38 132.5 0.0 3.8e-38 131.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK37326.1 - 1.7e-24 87.0 33.7 5.2e-23 82.2 0.0 7.0 6 2 0 6 6 4 2 AAA domain AAA_30 PF13604.6 KIK37326.1 - 1.9e-20 73.4 15.3 9.6e-06 25.4 0.0 7.1 6 1 1 7 7 7 5 AAA domain AAA_19 PF13245.6 KIK37326.1 - 1.3e-17 64.5 2.0 1.2e-07 32.2 0.0 5.8 4 3 0 5 5 4 3 AAA domain AAA_lid_6 PF17866.1 KIK37326.1 - 1e-16 60.9 14.0 1.6e-08 34.6 0.0 4.9 4 0 0 4 4 3 3 AAA lid domain AAA_5 PF07728.14 KIK37326.1 - 1.3e-14 54.3 0.1 0.011 15.7 0.0 5.1 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIK37326.1 - 2.1e-10 41.0 15.7 0.01 16.1 0.0 7.6 6 3 0 7 7 5 4 AAA domain AAA_18 PF13238.6 KIK37326.1 - 2.8e-10 40.9 0.9 3.3 8.2 0.0 6.2 5 0 0 5 5 5 2 AAA domain Mg_chelatase PF01078.21 KIK37326.1 - 2.8e-10 39.9 0.4 0.65 9.3 0.0 4.7 4 0 0 4 4 4 4 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KIK37326.1 - 4.1e-10 40.0 0.0 0.59 10.5 0.0 5.1 4 0 0 4 4 4 3 RNA helicase RuvB_N PF05496.12 KIK37326.1 - 2.5e-09 37.1 0.2 0.28 10.9 0.0 4.9 4 1 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KIK37326.1 - 5.7e-09 36.0 2.5 0.094 12.4 0.1 5.3 5 0 0 5 5 5 3 AAA domain Viral_helicase1 PF01443.18 KIK37326.1 - 7.8e-09 35.6 0.0 0.5 10.1 0.0 5.8 6 0 0 6 6 6 2 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 KIK37326.1 - 4.1e-08 33.2 0.5 5.8 6.6 0.0 5.4 5 0 0 5 5 5 0 IstB-like ATP binding protein Torsin PF06309.11 KIK37326.1 - 1.9e-07 31.3 0.0 4.1 7.5 0.0 4.6 4 0 0 4 4 4 1 Torsin Sigma54_activat PF00158.26 KIK37326.1 - 3e-07 30.3 1.1 3.2 7.4 0.0 5.3 5 1 0 5 5 5 2 Sigma-54 interaction domain AAA_16 PF13191.6 KIK37326.1 - 7.3e-07 29.7 26.7 0.044 14.2 0.0 6.7 6 0 0 6 6 5 3 AAA ATPase domain ResIII PF04851.15 KIK37326.1 - 9.8e-07 28.9 4.6 0.0012 18.9 0.0 5.1 5 1 1 6 6 4 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KIK37326.1 - 1.9e-06 27.5 1.4 1.2 8.6 0.0 5.5 5 0 0 5 5 5 1 PhoH-like protein AAA_7 PF12775.7 KIK37326.1 - 1.2e-05 24.9 0.3 6.8 6.2 0.0 4.4 4 0 0 4 4 4 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 KIK37326.1 - 0.00015 21.9 0.1 3.5 7.7 0.0 4.7 4 0 0 4 4 4 1 Sigma-54 interaction domain TsaE PF02367.17 KIK37326.1 - 0.00033 20.7 1.2 0.92 9.5 0.0 4.0 4 0 0 4 4 4 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 KIK37326.1 - 0.00034 20.6 0.1 10 6.0 0.0 4.3 4 0 0 4 4 4 0 Rad17 P-loop domain DUF2075 PF09848.9 KIK37326.1 - 0.00069 18.9 18.4 0.00074 18.9 0.0 6.9 6 2 1 7 7 6 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 KIK37326.1 - 0.0027 17.7 1.4 17 5.3 0.0 4.4 4 0 0 4 4 4 0 NTPase AAA_28 PF13521.6 KIK37326.1 - 0.0031 17.8 18.2 5.4 7.2 0.0 6.4 6 0 0 6 6 4 0 AAA domain AAA_33 PF13671.6 KIK37326.1 - 0.0035 17.5 24.7 0.43 10.7 0.0 6.0 6 0 0 6 6 4 3 AAA domain NACHT PF05729.12 KIK37326.1 - 0.0051 16.7 2.2 34 4.3 0.0 4.4 4 0 0 4 4 4 0 NACHT domain AAA_25 PF13481.6 KIK37326.1 - 0.0068 16.0 4.0 5 6.7 0.1 4.8 4 0 0 4 4 4 0 AAA domain KTI12 PF08433.10 KIK37326.1 - 0.0079 15.7 3.0 6.6 6.1 0.0 4.7 5 0 0 5 5 4 0 Chromatin associated protein KTI12 SRP54 PF00448.22 KIK37326.1 - 0.008 15.8 1.7 32 4.1 0.0 4.7 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain CbiA PF01656.23 KIK37326.1 - 0.011 15.7 0.3 20 5.2 0.0 4.3 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain ADK PF00406.22 KIK37326.1 - 0.022 14.8 2.0 7.5 6.6 0.1 3.9 3 0 0 3 3 3 0 Adenylate kinase RsgA_GTPase PF03193.16 KIK37326.1 - 0.13 12.2 0.6 24 4.8 0.1 3.9 4 0 0 4 4 4 0 RsgA GTPase ATPase PF06745.13 KIK37326.1 - 0.19 11.1 10.4 14 5.0 0.0 5.2 5 0 0 5 5 4 0 KaiC Helicase_RecD PF05127.14 KIK37326.1 - 0.31 10.9 0.0 0.31 10.9 0.0 4.7 6 1 0 6 6 4 0 Helicase SKI PF01202.22 KIK37326.1 - 1.1 9.4 12.9 7 6.8 0.0 5.6 5 0 0 5 5 4 0 Shikimate kinase ABC_tran PF00005.27 KIK37326.1 - 8.7 6.9 16.8 25 5.4 0.0 5.9 6 0 0 6 6 4 0 ABC transporter AAA PF00004.29 KIK37327.1 - 6.3e-44 149.6 0.0 1.4e-13 51.5 0.0 5.3 5 0 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 KIK37327.1 - 3.2e-38 131.4 0.0 7.2e-38 130.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK37327.1 - 2.9e-25 89.6 26.9 4.6e-24 85.6 0.0 6.3 6 0 0 6 6 5 2 AAA domain AAA_30 PF13604.6 KIK37327.1 - 7.6e-21 74.7 11.3 0.00015 21.6 0.0 6.6 6 2 1 7 7 5 5 AAA domain AAA_lid_6 PF17866.1 KIK37327.1 - 2e-17 63.1 1.0 1.7e-07 31.3 0.0 4.5 3 0 0 3 3 3 2 AAA lid domain AAA_19 PF13245.6 KIK37327.1 - 1e-16 61.6 7.0 1.3e-05 25.6 0.0 6.7 6 1 1 7 7 5 3 AAA domain AAA_22 PF13401.6 KIK37327.1 - 2.3e-15 57.1 2.8 0.012 15.9 0.0 7.2 5 3 1 6 6 6 3 AAA domain AAA_5 PF07728.14 KIK37327.1 - 1.1e-14 54.6 2.1 0.047 13.7 0.0 5.7 5 0 0 5 5 5 4 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KIK37327.1 - 8.3e-11 42.1 0.0 0.23 11.2 0.0 5.7 6 0 0 6 6 6 2 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 KIK37327.1 - 1.6e-09 37.7 0.1 0.27 11.0 0.0 4.8 4 1 0 4 4 4 3 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KIK37327.1 - 9.4e-09 35.9 14.4 0.041 14.3 0.0 6.2 6 0 0 6 6 4 3 AAA ATPase domain RNA_helicase PF00910.22 KIK37327.1 - 1.8e-08 34.7 0.6 3.5 8.0 0.0 5.4 5 0 0 5 5 4 2 RNA helicase IstB_IS21 PF01695.17 KIK37327.1 - 3.7e-08 33.3 0.1 0.98 9.1 0.0 4.6 4 0 0 4 4 4 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KIK37327.1 - 1.1e-07 31.5 5.5 0.44 9.9 0.0 5.0 6 0 0 6 6 4 3 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KIK37327.1 - 1.7e-07 31.8 11.7 1 9.9 0.0 6.3 6 0 0 6 6 5 2 AAA domain ResIII PF04851.15 KIK37327.1 - 5.1e-07 29.8 1.8 0.0021 18.1 0.0 5.1 6 1 0 6 6 4 1 Type III restriction enzyme, res subunit Torsin PF06309.11 KIK37327.1 - 3.6e-06 27.1 0.1 11 6.1 0.0 4.5 4 0 0 4 4 4 0 Torsin DUF2075 PF09848.9 KIK37327.1 - 4.7e-06 26.1 7.1 0.0038 16.5 0.0 6.2 5 2 1 6 6 6 1 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 KIK37327.1 - 4.9e-06 26.3 1.0 6.3 6.5 0.0 5.1 5 1 0 5 5 4 0 Sigma-54 interaction domain TniB PF05621.11 KIK37327.1 - 1.5e-05 24.5 0.0 13 5.2 0.0 5.6 5 0 0 5 5 5 0 Bacterial TniB protein PhoH PF02562.16 KIK37327.1 - 1.8e-05 24.3 0.2 4.1 6.8 0.0 5.0 5 0 0 5 5 5 1 PhoH-like protein AAA_24 PF13479.6 KIK37327.1 - 2e-05 24.4 8.0 1.9 8.1 0.0 5.5 6 0 0 6 6 5 2 AAA domain ATPase PF06745.13 KIK37327.1 - 2.2e-05 23.9 0.2 3.6 6.9 0.0 4.8 4 0 0 4 4 4 1 KaiC AAA_7 PF12775.7 KIK37327.1 - 3.6e-05 23.3 0.4 15 5.1 0.0 4.3 4 0 0 4 4 4 0 P-loop containing dynein motor region AAA_33 PF13671.6 KIK37327.1 - 0.00024 21.3 20.2 1.2 9.3 0.0 6.1 6 0 0 6 6 4 3 AAA domain Sigma54_activ_2 PF14532.6 KIK37327.1 - 0.00077 19.6 0.2 12 6.0 0.0 4.6 4 0 0 4 4 4 0 Sigma-54 interaction domain NTPase_1 PF03266.15 KIK37327.1 - 0.0009 19.2 1.1 17 5.3 0.0 4.5 4 0 0 4 4 4 0 NTPase Rad17 PF03215.15 KIK37327.1 - 0.001 19.0 0.1 6.2 6.7 0.0 3.9 4 0 0 4 4 4 0 Rad17 P-loop domain TsaE PF02367.17 KIK37327.1 - 0.0018 18.2 2.1 2.7 8.0 0.1 3.8 4 0 0 4 4 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KIK37327.1 - 0.0024 18.4 7.9 10 6.7 0.0 5.5 6 0 0 6 6 4 0 ABC transporter AAA_28 PF13521.6 KIK37327.1 - 0.0041 17.4 16.0 1.6 9.0 0.1 5.7 5 0 0 5 5 4 2 AAA domain NACHT PF05729.12 KIK37327.1 - 0.0045 16.9 1.6 40 4.1 0.0 4.6 4 0 0 4 4 4 0 NACHT domain Helicase_RecD PF05127.14 KIK37327.1 - 0.0083 16.0 0.0 0.32 10.8 0.0 3.5 3 0 0 3 3 3 1 Helicase CbiA PF01656.23 KIK37327.1 - 0.017 15.1 0.2 67 3.6 0.0 4.4 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 KIK37327.1 - 0.022 14.3 8.7 11 5.5 0.0 5.9 6 0 0 6 6 6 0 AAA domain KTI12 PF08433.10 KIK37327.1 - 0.041 13.3 4.9 5 6.5 0.0 4.8 5 0 0 5 5 5 0 Chromatin associated protein KTI12 NB-ARC PF00931.22 KIK37327.1 - 0.072 12.3 0.2 30 3.7 0.0 3.6 4 0 0 4 4 3 0 NB-ARC domain SRP54 PF00448.22 KIK37327.1 - 0.62 9.7 5.1 31 4.1 0.0 4.6 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain ADK PF00406.22 KIK37327.1 - 0.68 10.0 6.9 11 6.1 0.1 4.7 5 1 0 5 5 3 0 Adenylate kinase AAA_17 PF13207.6 KIK37327.1 - 2.7 8.4 27.9 4.2 7.8 0.0 6.6 6 1 1 7 7 5 0 AAA domain Aldo_ket_red PF00248.21 KIK37329.1 - 0.0085 15.3 0.0 0.017 14.3 0.0 1.5 1 0 0 1 1 1 1 Aldo/keto reductase family Carn_acyltransf PF00755.20 KIK37329.1 - 0.1 11.2 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Choline/Carnitine o-acyltransferase DUF3325 PF11804.8 KIK37330.1 - 0.14 12.3 0.2 0.38 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) PI-PLC-X PF00388.19 KIK37331.1 - 7.3e-17 61.3 0.0 1e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KIK37331.1 - 7.5e-07 29.5 0.1 1.2e-06 28.8 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain APCDDC PF14921.6 KIK37331.1 - 0.032 13.7 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Adenomatosis polyposis coli down-regulated 1 Glucan_synthase PF02364.15 KIK37332.1 - 1.4e-75 255.0 19.4 1.9e-45 155.4 1.0 3.1 1 1 2 3 3 3 3 1,3-beta-glucan synthase component Lamprin PF06403.11 KIK37334.1 - 5.8 6.9 12.1 47 3.9 4.2 3.2 1 1 2 3 3 3 0 Lamprin PAP2 PF01569.21 KIK37335.1 - 2.9e-15 56.2 5.2 2.9e-15 56.2 5.2 1.4 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KIK37335.1 - 0.11 12.1 10.7 1.4 8.6 10.7 2.5 1 1 0 1 1 1 0 PAP2 superfamily DEAD PF00270.29 KIK37336.1 - 0.00068 19.4 0.0 0.0014 18.4 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase NACHT PF05729.12 KIK37338.1 - 7.9e-07 29.1 0.0 3.7e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KIK37338.1 - 1.6e-05 25.3 0.1 4.3e-05 24.0 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain Torsin PF06309.11 KIK37338.1 - 0.0048 17.0 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 Torsin Parvo_NS1 PF01057.17 KIK37338.1 - 0.022 13.9 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 KIK37338.1 - 0.023 13.9 0.0 0.059 12.5 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 KIK37338.1 - 0.035 14.5 0.5 0.26 11.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KIK37338.1 - 0.05 12.9 0.0 0.12 11.6 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 KIK37338.1 - 0.053 13.4 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 KIK37338.1 - 0.084 13.2 0.3 0.72 10.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain PIF1 PF05970.14 KIK37338.1 - 0.17 11.0 0.9 6.8 5.8 0.0 2.5 3 0 0 3 3 3 0 PIF1-like helicase CENP-L PF13092.6 KIK37338.1 - 0.2 11.9 0.6 0.48 10.6 0.2 1.8 2 1 0 2 2 2 0 Kinetochore complex Sim4 subunit Fta1 IPPT PF01715.17 KIK37339.1 - 0.037 13.8 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 IPP transferase DUF2716 PF10898.8 KIK37339.1 - 0.11 12.9 0.1 0.23 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2716) Plavaka PF18759.1 KIK37340.1 - 2.4e-23 82.9 0.0 3e-15 56.3 0.1 2.2 2 0 0 2 2 2 2 Plavaka transposase zf-C2HC_2 PF13913.6 KIK37341.1 - 0.0027 17.6 0.4 0.0066 16.3 0.4 1.7 1 1 0 1 1 1 1 zinc-finger of a C2HC-type CBP_BcsQ PF06564.12 KIK37342.1 - 0.014 14.9 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ HCNGP PF07818.13 KIK37343.1 - 0.083 13.5 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 HCNGP-like protein MbtH PF03621.13 KIK37343.1 - 0.24 10.9 1.2 2 7.9 0.1 2.3 2 0 0 2 2 2 0 MbtH-like protein Plavaka PF18759.1 KIK37345.1 - 3.3e-23 82.4 0.1 7.1e-23 81.3 0.1 1.6 1 1 0 1 1 1 1 Plavaka transposase HUN PF08729.10 KIK37347.1 - 8.9e-15 54.4 0.7 8.9e-15 54.4 0.7 1.7 1 1 0 1 1 1 1 HPC2 and ubinuclein domain Sugar_tr PF00083.24 KIK37349.1 - 1.5e-91 307.5 22.7 1.7e-91 307.3 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK37349.1 - 3.2e-18 65.8 25.6 3.2e-18 65.8 25.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BTP PF05232.12 KIK37349.1 - 0.032 14.3 0.4 0.032 14.3 0.4 2.9 3 0 0 3 3 3 0 Chlorhexidine efflux transporter Aldedh PF00171.22 KIK37351.1 - 5.8e-82 275.6 0.0 6.9e-82 275.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fic PF02661.18 KIK37351.1 - 0.0072 17.2 0.0 0.05 14.5 0.0 2.3 2 0 0 2 2 2 1 Fic/DOC family Peptidase_S9 PF00326.21 KIK37352.1 - 8.7e-22 77.6 0.0 1.5e-14 54.0 0.0 2.7 1 1 1 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KIK37352.1 - 2e-05 24.0 0.0 5.2e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK37352.1 - 0.0039 16.9 0.1 0.19 11.3 0.0 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK37352.1 - 0.01 16.5 0.5 0.031 14.9 0.1 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Esterase PF00756.20 KIK37352.1 - 0.035 13.8 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Mito_fiss_Elm1 PF06258.11 KIK37352.1 - 0.042 13.0 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial fission ELM1 DUF2920 PF11144.8 KIK37352.1 - 0.097 11.8 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) ICMT PF04140.14 KIK37353.1 - 1.5e-15 57.3 4.1 7.1e-15 55.2 0.1 2.5 2 1 1 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK37353.1 - 9.8e-12 45.2 3.1 9.8e-12 45.2 3.1 2.2 2 1 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIK37353.1 - 3e-05 23.0 0.0 5.8e-05 22.0 0.0 1.4 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Ribo_biogen_C PF04034.13 KIK37354.1 - 0.11 12.3 0.0 0.45 10.2 0.0 1.9 2 0 0 2 2 2 0 Ribosome biogenesis protein, C-terminal PRY PF13765.6 KIK37354.1 - 0.4 10.3 2.6 0.85 9.3 0.2 2.4 2 0 0 2 2 2 0 SPRY-associated domain Importin_rep PF18773.1 KIK37355.1 - 2.7e-10 39.7 0.8 5.8e-10 38.7 0.8 1.6 1 0 0 1 1 1 1 Importin 13 repeat Xpo1 PF08389.12 KIK37355.1 - 5.2e-06 26.6 0.1 3e-05 24.1 0.0 2.5 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 KIK37355.1 - 0.00027 20.8 0.0 0.00071 19.4 0.0 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain Importin_rep_3 PF18806.1 KIK37355.1 - 0.0011 19.0 0.0 0.004 17.2 0.0 2.1 1 0 0 1 1 1 1 Importin 13 repeat HEAT_2 PF13646.6 KIK37355.1 - 0.02 15.3 0.2 1.9 8.9 0.0 3.7 3 0 0 3 3 3 0 HEAT repeats Aconitase PF00330.20 KIK37356.1 - 2.8e-152 508.0 0.0 3.4e-152 507.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KIK37356.1 - 2.4e-44 150.8 0.0 4e-44 150.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Peptidase_M56 PF05569.11 KIK37357.1 - 0.038 13.2 0.1 0.069 12.3 0.1 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 TMEM154 PF15102.6 KIK37357.1 - 0.73 9.7 3.3 2.8 7.9 3.3 2.0 1 1 0 1 1 1 0 TMEM154 protein family WD40 PF00400.32 KIK37359.1 - 6.2e-139 447.8 49.2 2e-10 41.1 0.2 14.9 15 0 0 15 15 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37359.1 - 2.1e-53 178.6 0.1 0.00034 20.9 0.0 14.3 1 1 12 14 14 14 14 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK37359.1 - 1.1e-38 133.0 9.8 0.0033 16.4 0.0 14.1 6 3 5 14 14 14 13 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK37359.1 - 2.7e-14 52.7 33.0 1.1 9.3 0.0 13.7 15 0 0 15 15 15 7 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK37359.1 - 4.7e-13 49.1 0.0 0.087 12.1 0.0 9.5 8 2 2 11 11 11 2 WD40-like domain Nup160 PF11715.8 KIK37359.1 - 2.3e-12 46.3 8.1 1.5 7.4 0.0 11.0 7 3 5 12 12 12 4 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK37359.1 - 1e-06 28.3 8.4 15 4.8 0.0 9.5 10 1 1 11 11 11 1 Neuroblastoma-amplified sequence, N terminal Peptidase_S9_N PF02897.15 KIK37359.1 - 1.6e-05 23.9 0.1 5.8 5.6 0.0 6.5 2 2 4 8 8 8 1 Prolyl oligopeptidase, N-terminal beta-propeller domain PQQ PF01011.21 KIK37359.1 - 0.00045 20.0 0.7 3.1 7.9 0.0 5.7 6 0 0 6 6 6 1 PQQ enzyme repeat Cuticle_4 PF15955.5 KIK37359.1 - 0.027 15.2 3.2 1.4e+02 3.3 0.0 6.4 7 0 0 7 7 6 0 Cuticle protein Ses_B PF17046.5 KIK37359.1 - 0.54 10.3 8.8 61 3.7 0.0 5.8 5 0 0 5 5 5 0 SesB domain on fungal death-pathway protein GMC_oxred_C PF05199.13 KIK37361.1 - 2e-14 54.3 0.1 2.2e-14 54.2 0.1 1.0 1 0 0 1 1 1 1 GMC oxidoreductase RTC4 PF14474.6 KIK37361.1 - 0.099 12.8 0.0 0.099 12.8 0.0 1.1 1 0 0 1 1 1 0 RTC4-like domain GMC_oxred_N PF00732.19 KIK37362.1 - 1.5e-60 205.1 0.0 1.9e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK37362.1 - 2.8e-05 24.7 0.0 5.6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK37362.1 - 0.019 14.0 0.1 0.049 12.7 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK37362.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KIK37366.1 - 3.7e-27 95.3 1.1 1.1e-14 54.2 0.0 2.6 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KIK37366.1 - 5.5e-13 48.9 0.0 1.5e-12 47.5 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KIK37366.1 - 3.8e-07 30.3 0.1 1.1e-06 28.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK37366.1 - 4.4e-06 26.5 0.1 0.0012 18.5 0.1 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KIK37366.1 - 4.9e-06 26.2 0.1 1.9e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK37366.1 - 1.7e-05 24.2 0.0 3.1e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK37366.1 - 2e-05 23.8 0.0 0.00033 19.9 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KIK37366.1 - 0.00014 20.7 0.0 0.00023 20.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KIK37366.1 - 0.00015 21.0 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KIK37366.1 - 0.0068 16.9 0.0 0.067 13.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK37366.1 - 0.033 13.4 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 KIK37366.1 - 0.062 12.9 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KIK37366.1 - 0.066 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KIK37366.1 - 0.14 11.4 0.1 0.22 10.7 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Defensin_2 PF01097.18 KIK37367.1 - 0.028 14.3 0.1 0.049 13.6 0.1 1.4 1 0 0 1 1 1 0 Arthropod defensin Methyltransf_2 PF00891.18 KIK37368.1 - 3.6e-14 52.6 0.0 3e-13 49.5 0.0 2.0 1 1 0 1 1 1 1 O-methyltransferase domain MarR_2 PF12802.7 KIK37368.1 - 0.0031 17.3 0.0 0.012 15.5 0.0 2.1 1 1 0 1 1 1 1 MarR family MTS PF05175.14 KIK37368.1 - 0.0039 16.7 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KIK37368.1 - 0.0081 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KIK37368.1 - 0.012 16.3 0.0 0.024 15.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MarR PF01047.22 KIK37368.1 - 0.02 14.8 0.0 0.068 13.1 0.0 2.0 1 0 0 1 1 1 0 MarR family RPA_C PF08784.11 KIK37368.1 - 0.076 13.7 0.0 0.16 12.7 0.0 1.5 1 0 0 1 1 1 0 Replication protein A C terminal Methyltransf_25 PF13649.6 KIK37370.1 - 1.2e-07 32.4 0.0 2.7e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK37370.1 - 6e-05 23.6 0.0 0.00011 22.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK37370.1 - 0.00026 20.4 0.0 0.00041 19.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KIK37370.1 - 0.00032 20.6 0.1 0.00048 20.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK37370.1 - 0.0024 18.6 0.0 0.0045 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KIK37370.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DUF2398 PF09661.10 KIK37373.1 - 0.14 11.4 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2398) Macoilin PF09726.9 KIK37374.1 - 3.5 6.1 8.6 4.3 5.8 8.6 1.1 1 0 0 1 1 1 0 Macoilin family Dna2 PF08696.11 KIK37375.1 - 6.1e-58 196.0 0.0 9.7e-58 195.3 0.0 1.3 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KIK37375.1 - 3.6e-53 180.2 0.0 5.8e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK37375.1 - 4.1e-13 49.7 0.0 9.3e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIK37375.1 - 4e-09 36.5 0.2 1.7e-08 34.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain Cas_Cas4 PF01930.17 KIK37375.1 - 2.9e-06 27.5 0.5 1.8e-05 24.9 0.5 2.2 1 1 0 1 1 1 1 Domain of unknown function DUF83 AAA_19 PF13245.6 KIK37375.1 - 3.4e-06 27.5 0.1 7.8e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 KIK37375.1 - 1.1e-05 25.5 0.0 7.1e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_16 PF13191.6 KIK37375.1 - 0.00099 19.5 1.5 0.016 15.6 0.1 3.1 3 1 0 3 3 3 1 AAA ATPase domain Viral_helicase1 PF01443.18 KIK37375.1 - 0.002 17.9 0.0 0.18 11.5 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 KIK37375.1 - 0.0094 16.5 0.3 0.069 13.7 0.0 2.6 3 0 0 3 3 2 1 AAA domain UvrD-helicase PF00580.21 KIK37375.1 - 0.012 15.1 0.1 0.028 13.9 0.1 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 KIK37375.1 - 0.013 15.1 0.5 0.027 14.1 0.5 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Helicase_RecD PF05127.14 KIK37375.1 - 0.013 15.3 0.0 0.034 14.0 0.0 1.7 1 0 0 1 1 1 0 Helicase AAA PF00004.29 KIK37375.1 - 0.019 15.4 0.3 0.086 13.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KIK37375.1 - 0.047 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KIK37375.1 - 0.07 12.7 0.1 0.42 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KIK37375.1 - 0.074 12.0 0.0 0.18 10.7 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 KIK37375.1 - 0.076 13.5 0.0 0.35 11.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter TrwB_AAD_bind PF10412.9 KIK37375.1 - 0.08 11.8 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.17 KIK37375.1 - 0.09 12.5 0.2 0.26 11.0 0.0 1.9 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_29 PF13555.6 KIK37375.1 - 0.093 12.5 0.2 0.22 11.3 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 KIK37375.1 - 0.095 12.3 0.0 0.44 10.1 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KIK37375.1 - 0.1 12.1 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KIK37375.1 - 0.12 12.5 0.2 0.53 10.4 0.0 2.3 2 0 0 2 2 1 0 AAA domain CbiA PF01656.23 KIK37375.1 - 0.22 11.6 1.8 0.45 10.6 0.5 2.1 2 0 0 2 2 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TEA PF01285.18 KIK37377.1 - 1.4e-20 73.1 0.0 2.4e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 TEA/ATTS domain Cellulase PF00150.18 KIK37378.1 - 0.0003 20.3 0.0 0.00061 19.3 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RhoGEF PF00621.20 KIK37382.1 - 6.9e-25 88.3 0.0 7e-20 72.0 0.0 2.6 2 1 0 2 2 2 2 RhoGEF domain zf-H2C2_2 PF13465.6 KIK37383.1 - 0.00049 20.4 1.0 0.00049 20.4 1.0 1.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2HC_2 PF13913.6 KIK37383.1 - 0.022 14.7 0.3 0.022 14.7 0.3 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KIK37383.1 - 0.044 13.8 0.2 0.12 12.4 0.2 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KIK37383.1 - 0.18 12.7 0.7 1.1 10.3 0.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Pyr_redox_2 PF07992.14 KIK37384.1 - 2.2e-64 217.5 0.0 3e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KIK37384.1 - 1.3e-32 112.3 0.2 2.4e-32 111.5 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KIK37384.1 - 5.4e-23 81.4 2.8 4.7e-20 71.9 0.2 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK37384.1 - 8e-13 48.3 0.5 2e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIK37384.1 - 7.1e-08 32.2 0.0 1.4e-07 31.3 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIK37384.1 - 1.3e-07 30.6 0.4 0.0045 15.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 KIK37384.1 - 0.00018 21.6 0.5 0.00018 21.6 0.5 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK37384.1 - 0.0017 17.5 0.1 1.5 7.8 0.0 2.8 2 2 0 2 2 2 2 Lycopene cyclase protein K_oxygenase PF13434.6 KIK37384.1 - 0.0036 16.5 0.0 0.048 12.8 0.0 2.2 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KIK37384.1 - 0.0057 15.8 0.4 0.0057 15.8 0.4 2.1 2 1 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KIK37384.1 - 0.0092 15.1 0.7 0.021 13.9 0.7 1.6 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIK37384.1 - 0.022 14.4 1.7 1.7 8.1 0.0 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.17 KIK37384.1 - 0.038 13.2 0.2 0.098 11.9 0.0 1.8 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 KIK37384.1 - 0.05 13.6 0.3 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KIK37384.1 - 0.056 12.7 0.0 3 7.1 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 KIK37384.1 - 0.07 12.4 0.2 0.42 9.8 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase CoA_trans PF01144.23 KIK37387.1 - 6.8e-102 339.4 1.1 8.3e-62 208.4 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KIK37387.1 - 0.00027 20.9 0.0 0.00051 20.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Cofilin_ADF PF00241.20 KIK37388.1 - 2.3e-31 108.1 0.0 1.8e-15 56.8 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein F-box-like PF12937.7 KIK37389.1 - 1.1e-07 31.6 1.2 8.8e-07 28.7 0.2 2.8 3 0 0 3 3 3 1 F-box-like DUF3535 PF12054.8 KIK37390.1 - 1.5e-103 347.4 1.0 1.5e-103 347.4 1.0 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KIK37390.1 - 1.6e-64 217.8 0.0 3.2e-64 216.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK37390.1 - 1.4e-16 60.8 0.0 3.3e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KIK37390.1 - 2.5e-14 52.1 12.1 0.36 11.2 0.2 10.8 11 0 0 11 11 11 4 HEAT repeat ResIII PF04851.15 KIK37390.1 - 7.8e-05 22.7 0.0 0.00019 21.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HEAT_EZ PF13513.6 KIK37390.1 - 0.00019 21.8 17.4 5.6 7.6 0.0 9.1 9 1 1 10 10 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KIK37390.1 - 0.0029 18.1 0.1 4.8 7.8 0.0 3.0 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 KIK37390.1 - 0.0085 16.0 0.1 0.041 13.8 0.1 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 KIK37390.1 - 0.015 15.6 15.4 2.9 8.4 0.0 7.7 7 2 0 7 7 7 0 HEAT repeats ERCC3_RAD25_C PF16203.5 KIK37390.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF3391 PF11871.8 KIK37390.1 - 0.18 12.4 1.5 0.34 11.5 0.0 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF3391) Cupin_8 PF13621.6 KIK37391.1 - 6e-31 108.1 0.0 8.5e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KIK37391.1 - 4.8e-06 26.3 0.0 1.1e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 KIK37391.1 - 0.0015 19.0 0.0 0.027 14.9 0.0 2.3 1 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KIK37391.1 - 0.0065 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KIK37391.1 - 0.09 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_1 PF00190.22 KIK37391.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Cupin SOG2 PF10428.9 KIK37392.1 - 3.4e-76 257.5 2.2 3.4e-76 257.5 2.2 2.9 2 1 0 2 2 2 1 RAM signalling pathway protein LRR_8 PF13855.6 KIK37392.1 - 8.7e-16 57.4 1.2 5.7e-08 32.4 0.0 3.4 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KIK37392.1 - 5.5e-13 48.9 0.5 1.5e-06 28.5 0.2 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KIK37392.1 - 0.0069 16.8 4.7 6.5 7.7 0.1 4.7 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 KIK37392.1 - 0.57 10.4 3.9 12 6.2 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeat FYVE PF01363.21 KIK37393.1 - 1.1e-15 57.5 3.6 1.8e-15 56.9 3.6 1.3 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 KIK37393.1 - 1.4e-13 50.4 0.4 3.3e-13 49.1 0.4 1.7 1 0 0 1 1 1 1 Rabenosyn Rab binding domain FYVE_2 PF02318.16 KIK37393.1 - 0.039 14.2 0.1 0.1 12.8 0.1 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C2HC5 PF06221.13 KIK37393.1 - 0.051 13.6 8.6 0.042 13.8 6.3 1.9 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Copper-bind PF00127.20 KIK37394.1 - 8.7e-05 22.9 3.3 0.29 11.6 0.4 3.0 2 1 1 3 3 3 2 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.17 KIK37394.1 - 0.00061 19.8 5.0 0.32 11.0 0.9 3.6 2 2 0 2 2 2 2 Plastocyanin-like domain Cupredoxin_1 PF13473.6 KIK37394.1 - 0.00096 19.2 0.1 0.029 14.5 0.1 2.5 2 0 0 2 2 2 1 Cupredoxin-like domain B12-binding PF02310.19 KIK37394.1 - 0.0093 16.0 0.4 2.6 8.1 0.1 2.6 3 0 0 3 3 3 2 B12 binding domain PUMA PF15826.5 KIK37394.1 - 3.6 7.7 7.9 0.76 9.9 3.8 2.0 2 1 0 2 2 2 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis MUG113 PF13455.6 KIK37396.1 - 3.6e-10 40.4 0.4 1.3e-09 38.5 0.1 2.2 2 1 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KIK37396.1 - 2e-09 37.9 1.7 1.2e-07 32.2 0.0 3.0 3 0 0 3 3 3 1 T5orf172 domain DUF1419 PF07215.11 KIK37396.1 - 0.053 13.6 0.0 4.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1419) LRR_8 PF13855.6 KIK37397.1 - 2.5e-11 43.2 5.5 9.9e-08 31.6 3.3 2.3 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KIK37397.1 - 1.6e-06 28.4 10.8 0.0019 18.6 1.7 3.4 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) RA PF00788.23 KIK37397.1 - 0.0089 16.6 0.0 0.017 15.8 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_9 PF14580.6 KIK37397.1 - 0.18 11.3 1.7 0.35 10.3 0.6 1.9 1 1 1 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 KIK37397.1 - 1.2 9.4 12.3 0.47 10.6 0.3 4.4 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 KIK37397.1 - 9.4 7.2 13.5 88 4.3 0.0 5.5 3 1 1 4 4 4 0 Leucine Rich Repeat Mg_trans_NIPA PF05653.14 KIK37398.1 - 1.8e-78 263.6 30.0 2.4e-78 263.3 30.0 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KIK37398.1 - 1e-06 29.0 8.3 1e-06 29.0 8.3 3.8 3 1 0 3 3 3 2 EamA-like transporter family Glyco_hydro_18 PF00704.28 KIK37399.1 - 1.2e-59 202.6 7.2 1.5e-59 202.3 7.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GHL10 PF02638.15 KIK37399.1 - 0.004 16.3 0.1 0.015 14.4 0.0 1.8 1 1 1 2 2 2 1 Glycosyl hydrolase-like 10 Zn_clus PF00172.18 KIK37400.1 - 7e-05 22.9 5.9 0.00012 22.2 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPC22 PF04573.12 KIK37403.1 - 1.5e-50 171.0 0.1 1.7e-50 170.9 0.1 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Acyltransferase PF01553.21 KIK37405.1 - 1.1e-17 64.0 0.0 1.7e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Lipase_3 PF01764.25 KIK37407.1 - 4.2e-27 94.8 0.0 5.7e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.20 KIK37407.1 - 0.0072 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase S-methyl_trans PF02574.16 KIK37409.1 - 1.8e-50 172.2 0.0 2.3e-50 171.9 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase AnfO_nitrog PF09582.10 KIK37409.1 - 0.06 12.7 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Phycobilisome PF00502.19 KIK37409.1 - 0.088 12.7 1.3 1.9 8.4 0.1 2.5 3 0 0 3 3 3 0 Phycobilisome protein TPR_12 PF13424.6 KIK37410.1 - 0.0028 17.9 0.1 0.54 10.6 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KIK37410.1 - 0.042 13.7 0.8 7.8 6.5 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat API5 PF05918.11 KIK37411.1 - 1.1e-23 83.9 0.6 1.7e-23 83.3 0.6 1.2 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.6 KIK37411.1 - 3.9e-05 23.9 0.2 0.00049 20.4 0.0 2.6 2 1 1 3 3 3 1 HEAT repeats Adaptin_N PF01602.20 KIK37411.1 - 0.0042 15.7 0.2 0.0075 14.9 0.2 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KIK37411.1 - 0.077 13.0 0.4 0.16 12.0 0.4 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Use1 PF09753.9 KIK37412.1 - 1.1e-18 67.9 0.0 2.2e-18 66.9 0.0 1.5 2 0 0 2 2 2 1 Membrane fusion protein Use1 Chitin_synth_2 PF03142.15 KIK37413.1 - 8.4e-79 265.6 4.6 9.5e-79 265.4 4.6 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 KIK37413.1 - 0.037 13.9 0.1 0.054 13.4 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Pkinase PF00069.25 KIK37414.1 - 7.3e-60 202.6 0.0 2.2e-59 201.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK37414.1 - 2.4e-27 95.9 0.3 1.9e-19 70.0 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIK37414.1 - 0.00059 19.2 0.3 0.014 14.7 0.0 2.6 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 KIK37414.1 - 0.004 16.5 0.0 0.01 15.2 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK37414.1 - 0.0094 15.9 0.1 0.068 13.1 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK37414.1 - 0.015 14.3 0.0 0.025 13.5 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Spindle_Spc25 PF08234.12 KIK37415.1 - 7.7e-22 77.3 0.4 2.5e-21 75.6 0.4 1.9 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Spc7 PF08317.11 KIK37415.1 - 0.021 13.7 11.2 0.028 13.3 11.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PI3K_P85_iSH2 PF16454.5 KIK37415.1 - 0.55 9.8 10.3 0.27 10.8 5.4 2.1 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4407 PF14362.6 KIK37415.1 - 0.77 9.0 11.5 1 8.7 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 KIK37415.1 - 1.2 9.6 12.0 1.4 9.4 8.9 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4200 PF13863.6 KIK37415.1 - 2.6 8.5 17.2 1.3 9.4 13.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) F-box-like PF12937.7 KIK37416.1 - 2.9e-05 23.9 0.1 5.1e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK37416.1 - 0.00014 21.6 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 F-box domain Glycos_transf_2 PF00535.26 KIK37417.1 - 3.7e-31 108.2 0.0 4.6e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIK37417.1 - 1.4e-13 51.3 0.0 1.9e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KIK37417.1 - 0.00036 20.1 0.0 0.00046 19.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7N PF13733.6 KIK37417.1 - 0.064 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 LSM PF01423.22 KIK37418.1 - 6.5e-11 41.8 0.1 1e-10 41.1 0.1 1.3 1 0 0 1 1 1 1 LSM domain Sel1 PF08238.12 KIK37419.1 - 9.6e-16 57.9 8.6 2.7e-05 24.7 0.5 4.0 4 0 0 4 4 4 3 Sel1 repeat IlvN PF07991.12 KIK37420.1 - 6.8e-46 155.9 0.0 1.1e-45 155.2 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KIK37420.1 - 2e-39 135.1 0.0 3.9e-39 134.2 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain HA2 PF04408.23 KIK37421.1 - 2.5e-22 79.2 0.0 2.5e-22 79.2 0.0 2.9 4 0 0 4 4 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIK37421.1 - 2.2e-16 60.0 0.0 6.2e-16 58.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KIK37421.1 - 6.5e-09 35.8 0.0 1.2e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KIK37421.1 - 2.6e-06 27.7 0.1 6.4e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIK37421.1 - 3e-05 23.9 0.3 0.0001 22.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KIK37421.1 - 0.00022 21.6 0.0 0.00047 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KIK37421.1 - 0.0034 16.7 0.0 0.0058 15.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KIK37421.1 - 0.0056 16.7 0.2 0.043 13.8 0.2 2.3 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 KIK37421.1 - 0.0071 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 KaiC T2SSE PF00437.20 KIK37421.1 - 0.0071 15.4 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 KIK37421.1 - 0.015 15.4 0.0 8.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 KIK37421.1 - 0.028 14.1 0.0 0.091 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIK37421.1 - 0.031 14.8 0.1 0.36 11.4 0.1 2.5 1 1 0 2 2 2 0 ABC transporter PhoH PF02562.16 KIK37421.1 - 0.047 13.1 0.0 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein SRP54 PF00448.22 KIK37421.1 - 0.055 13.1 0.1 0.14 11.8 0.1 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.12 KIK37421.1 - 0.15 12.0 0.2 0.61 10.0 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 KIK37421.1 - 0.17 12.2 1.3 0.36 11.2 0.0 2.2 3 0 0 3 3 2 0 AAA ATPase domain WRC PF08879.10 KIK37422.1 - 0.079 12.7 2.0 0.14 11.9 0.1 2.1 2 0 0 2 2 2 0 WRC PBP PF01161.20 KIK37424.1 - 4.4e-15 56.2 0.3 1e-14 55.0 0.3 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein FYVE PF01363.21 KIK37425.1 - 2.8e-16 59.4 4.7 2.8e-16 59.4 4.7 1.8 2 0 0 2 2 2 1 FYVE zinc finger PHD PF00628.29 KIK37426.1 - 5.8e-11 42.1 4.8 1e-10 41.4 4.8 1.4 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 KIK37426.1 - 0.0011 18.6 1.4 0.0024 17.5 1.4 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 KIK37426.1 - 0.0092 15.5 2.3 0.018 14.6 2.3 1.5 1 0 0 1 1 1 1 PHD-finger PHD_4 PF16866.5 KIK37426.1 - 0.22 11.6 3.3 0.45 10.7 3.3 1.5 1 0 0 1 1 1 0 PHD-finger zf-CW PF07496.15 KIK37426.1 - 0.22 11.5 1.0 0.58 10.2 1.0 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger Prok-RING_1 PF14446.6 KIK37426.1 - 1.2 9.1 4.1 2.8 7.9 4.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DNA_methylase PF00145.17 KIK37427.1 - 1.4e-22 80.5 0.0 1.6e-22 80.3 0.0 1.0 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase UvrD_C_2 PF13538.6 KIK37428.1 - 0.00021 21.1 1.3 0.0014 18.4 1.3 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF2106 PF09879.9 KIK37430.1 - 0.13 11.7 0.0 0.14 11.7 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) NiFe-hyd_HybE PF11939.8 KIK37431.1 - 0.18 11.7 0.1 0.32 10.9 0.1 1.4 1 0 0 1 1 1 0 [NiFe]-hydrogenase assembly, chaperone, HybE MCM_OB PF17207.3 KIK37432.1 - 0.0011 18.8 1.0 0.0014 18.5 1.0 1.1 1 0 0 1 1 1 1 MCM OB domain DUF3216 PF11505.8 KIK37434.1 - 0.11 12.7 0.5 0.36 11.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) zf-RVT PF13966.6 KIK37435.1 - 2.2e-06 28.3 0.3 4e-06 27.4 0.3 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 KIK37436.1 - 0.022 14.3 0.0 0.022 14.3 0.0 1.0 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Troponin PF00992.20 KIK37437.1 - 0.059 13.7 0.3 0.088 13.1 0.3 1.2 1 0 0 1 1 1 0 Troponin KDZ PF18758.1 KIK37440.1 - 0.0052 16.4 0.3 0.012 15.3 0.0 1.6 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase DUF1548 PF07579.11 KIK37441.1 - 0.018 15.4 2.2 0.04 14.3 2.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) ORC2 PF04084.14 KIK37441.1 - 0.029 13.3 0.6 0.04 12.8 0.6 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 2 RasGEF_N PF00618.20 KIK37441.1 - 0.033 14.4 2.1 0.057 13.6 2.1 1.4 1 0 0 1 1 1 0 RasGEF N-terminal motif Dimer_Tnp_hAT PF05699.14 KIK37442.1 - 4e-11 42.5 0.3 4.7e-11 42.3 0.3 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zinc_ribbon_10 PF10058.9 KIK37442.1 - 0.058 13.1 0.1 0.12 12.1 0.1 1.5 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein DFF40 PF09230.10 KIK37443.1 - 0.13 11.9 2.5 0.14 11.7 2.5 1.0 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa MarR PF01047.22 KIK37443.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 MarR family B PF02216.16 KIK37446.1 - 0.078 13.0 0.3 0.2 11.7 0.3 1.6 1 0 0 1 1 1 0 B domain KDZ PF18758.1 KIK37448.1 - 5.7e-79 264.8 0.1 1.2e-78 263.8 0.1 1.6 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Penaeidin PF05927.11 KIK37448.1 - 0.066 14.0 0.0 0.22 12.3 0.0 1.8 1 0 0 1 1 1 0 Penaeidin ANAPC16 PF17256.2 KIK37451.1 - 0.059 13.7 0.0 0.31 11.5 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, subunit 16 DUF899 PF05988.12 KIK37453.1 - 0.057 12.9 0.1 0.075 12.6 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) BES1_N PF05687.13 KIK37454.1 - 0.2 12.0 7.0 0.35 11.3 7.0 1.3 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal EBP50_C PF09007.11 KIK37454.1 - 0.44 11.6 7.8 0.9 10.5 7.8 1.5 1 0 0 1 1 1 0 EBP50, C-terminal Kei1 PF08552.11 KIK37454.1 - 1 9.2 3.7 1.9 8.3 3.7 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Tim54 PF11711.8 KIK37454.1 - 1.3 7.7 2.5 1.8 7.3 2.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nucleo_P87 PF07267.11 KIK37454.1 - 2.7 6.8 10.1 3.5 6.4 10.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SOG2 PF10428.9 KIK37458.1 - 3 6.9 17.4 3.9 6.6 17.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Amidohydro_1 PF01979.20 KIK37459.1 - 1.5e-65 221.8 1.7 2.3e-65 221.2 1.7 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KIK37459.1 - 2.3e-54 182.9 2.6 5.3e-54 181.7 2.6 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KIK37459.1 - 3e-42 142.6 0.1 8.8e-42 141.1 0.1 1.8 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 KIK37459.1 - 4.3e-40 136.0 0.0 9.8e-40 134.9 0.0 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 KIK37459.1 - 1.1e-05 25.1 0.1 0.00033 20.2 0.0 2.4 2 1 0 2 2 2 1 Amidohydrolase family Mito_carr PF00153.27 KIK37461.1 - 1.1e-58 195.2 4.3 3.2e-23 81.5 0.7 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Vps39_1 PF10366.9 KIK37463.1 - 4e-25 88.2 0.1 4e-25 88.2 0.1 3.2 3 1 1 4 4 4 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KIK37463.1 - 6.4e-24 84.5 0.2 1.6e-23 83.2 0.2 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 KIK37463.1 - 5e-13 49.1 3.2 3.1e-09 36.9 0.6 2.4 2 0 0 2 2 2 2 Region in Clathrin and VPS CNH PF00780.22 KIK37463.1 - 5.5e-13 49.2 0.0 2.1e-12 47.2 0.0 2.0 1 1 0 1 1 1 1 CNH domain TPR_1 PF00515.28 KIK37463.1 - 0.00039 20.1 3.7 3.8 7.5 1.7 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK37463.1 - 0.17 12.0 1.9 1e+02 3.3 0.0 4.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK37463.1 - 3.2 8.1 13.5 15 6.0 0.6 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-RVT PF13966.6 KIK37464.1 - 3.3e-05 24.5 0.2 5.1e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF953 PF06110.11 KIK37464.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) RVT_1 PF00078.27 KIK37465.1 - 2.6e-06 27.1 0.0 2.9e-06 27.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RPW8 PF05659.11 KIK37467.1 - 0.14 11.8 0.4 0.25 11.0 0.4 1.3 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 WD40 PF00400.32 KIK37468.1 - 1e-35 121.1 17.9 1.2e-07 32.3 0.9 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37468.1 - 2e-15 56.9 2.2 0.00015 22.0 0.0 4.2 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK37468.1 - 5.8e-09 35.1 3.0 0.00019 20.3 0.0 3.3 2 1 0 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK37468.1 - 7.5e-05 21.8 0.0 0.16 10.9 0.0 3.8 1 1 4 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KIK37468.1 - 0.0043 15.8 0.1 0.28 9.9 0.0 2.7 1 1 1 2 2 2 1 Nup133 N terminal like Nbas_N PF15492.6 KIK37468.1 - 0.012 14.9 0.1 0.11 11.8 0.0 2.3 1 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 KIK37468.1 - 0.083 11.2 0.0 0.95 7.7 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 KIK37469.1 - 1.1e-40 136.8 28.3 4.2e-08 33.7 0.7 6.4 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37469.1 - 1.3e-16 60.7 2.3 0.00063 20.0 0.1 5.7 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK37469.1 - 4.3e-08 32.5 0.1 0.99 8.3 0.0 4.9 1 1 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK37469.1 - 0.00011 21.7 0.0 0.031 13.6 0.0 3.1 2 1 1 3 3 3 1 WD40-like domain Nup160 PF11715.8 KIK37469.1 - 0.00016 20.5 5.6 0.11 11.2 0.0 3.7 3 1 0 4 4 4 3 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK37469.1 - 0.00019 20.9 1.0 0.58 9.4 0.0 3.7 2 2 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KIK37469.1 - 0.00045 20.1 2.2 14 5.7 0.1 5.6 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KIK37469.1 - 0.0035 15.9 0.1 2.6 6.5 0.0 2.9 1 1 2 3 3 3 2 Cytochrome D1 heme domain RAB3GAP2_N PF14655.6 KIK37469.1 - 0.0096 15.2 1.0 0.034 13.4 0.1 2.2 2 1 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus PDR_assoc PF08370.11 KIK37471.1 - 0.071 12.9 0.2 2.7 7.8 0.0 2.6 2 0 0 2 2 2 0 Plant PDR ABC transporter associated AA_permease_2 PF13520.6 KIK37472.1 - 3.9e-59 200.6 63.7 5.1e-59 200.2 63.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK37472.1 - 9.3e-13 47.6 55.6 1.3e-12 47.1 55.6 1.1 1 0 0 1 1 1 1 Amino acid permease PalH PF08733.10 KIK37472.1 - 0.29 10.1 11.0 0.67 8.9 11.0 1.7 1 0 0 1 1 1 0 PalH/RIM21 SNF2_N PF00176.23 KIK37473.1 - 2.3e-47 161.4 0.0 3.6e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK37473.1 - 5.6e-22 78.2 0.0 2.5e-18 66.4 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KIK37473.1 - 7.6e-07 29.3 0.0 5.7e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KIK37473.1 - 0.0002 20.7 0.0 0.0004 19.7 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase VIGSSK PF14773.6 KIK37473.1 - 0.0003 20.8 1.0 0.00063 19.8 0.0 2.1 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal SWI2_SNF2 PF18766.1 KIK37473.1 - 0.017 14.8 0.0 0.047 13.3 0.0 1.7 2 0 0 2 2 2 0 SWI2/SNF2 ATPase HMG_box PF00505.19 KIK37474.1 - 2e-22 79.3 0.7 2e-22 79.3 0.7 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK37474.1 - 1.1e-16 61.2 0.5 1.1e-16 61.2 0.5 2.0 2 1 0 2 2 2 1 HMG-box domain CHDNT PF08073.12 KIK37474.1 - 0.00067 19.6 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain YABBY PF04690.13 KIK37474.1 - 0.0051 17.4 0.4 0.0051 17.4 0.4 1.9 1 1 1 2 2 2 1 YABBY protein Imm75 PF15660.6 KIK37475.1 - 0.095 13.0 0.0 0.28 11.5 0.0 1.7 2 0 0 2 2 2 0 Putative Immunity protein 75 SUI1 PF01253.22 KIK37476.1 - 2.4e-19 69.6 0.3 6.7e-19 68.2 0.0 1.9 2 0 0 2 2 2 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 KIK37476.1 - 3.7e-14 53.2 0.0 1.7e-13 51.1 0.0 2.2 2 0 0 2 2 2 1 Pre-PUA-like domain PUA PF01472.20 KIK37476.1 - 0.00012 22.0 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 PUA domain Img2 PF05046.14 KIK37476.1 - 0.16 12.3 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) RrnaAD PF00398.20 KIK37477.1 - 1.2e-56 191.7 0.0 1.6e-56 191.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KIK37477.1 - 3.2e-07 31.0 0.0 5.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK37477.1 - 1.2e-05 25.9 0.0 2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK37477.1 - 6.1e-05 22.9 0.0 8.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIK37477.1 - 0.00011 22.0 0.0 0.00027 20.8 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KIK37477.1 - 0.00016 21.1 0.0 0.00033 20.0 0.0 1.4 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KIK37477.1 - 0.00032 21.4 0.0 0.00064 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK37477.1 - 0.00033 20.2 0.0 0.00046 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KIK37477.1 - 0.0031 16.9 0.0 0.0044 16.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_28 PF02636.17 KIK37477.1 - 0.012 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 KIK37477.1 - 0.027 13.8 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.11 KIK37477.1 - 0.06 13.0 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) DREV PF05219.12 KIK37477.1 - 0.061 12.4 0.0 0.083 12.0 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase DOT1 PF08123.13 KIK37477.1 - 0.085 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Met_10 PF02475.16 KIK37477.1 - 0.099 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_31 PF13847.6 KIK37477.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TauD PF02668.16 KIK37479.1 - 2.3e-09 37.5 0.1 4.3e-08 33.3 0.1 2.0 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HA PF03457.14 KIK37481.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.7 1 1 0 1 1 1 0 Helicase associated domain GATA PF00320.27 KIK37483.1 - 1.4e-12 47.0 5.2 2.6e-12 46.1 5.2 1.4 1 0 0 1 1 1 1 GATA zinc finger DUF1751 PF08551.10 KIK37485.1 - 0.29 11.7 6.4 0.075 13.6 2.3 1.9 1 1 1 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) SCAMP PF04144.13 KIK37485.1 - 0.86 9.9 9.9 1.3 9.3 9.9 1.3 1 0 0 1 1 1 0 SCAMP family SID-1_RNA_chan PF13965.6 KIK37485.1 - 2 6.7 5.1 1.8 6.9 5.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 zf-C2H2 PF00096.26 KIK37491.1 - 5.6e-05 23.4 8.7 0.00023 21.5 0.6 3.3 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK37491.1 - 0.00068 20.3 8.9 0.015 16.1 0.3 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KIK37491.1 - 0.01 15.5 2.3 0.031 14.0 0.2 2.6 2 1 1 3 3 3 0 zinc-finger C2H2-type zf-LYAR PF08790.11 KIK37491.1 - 0.011 15.6 1.0 0.039 13.9 0.1 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 KIK37491.1 - 0.019 15.0 6.0 0.027 14.5 0.1 3.0 3 1 0 3 3 3 0 C2H2-type zinc finger Zn_ribbon_recom PF13408.6 KIK37491.1 - 0.084 13.4 4.7 0.43 11.1 0.2 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Zn-ribbon_8 PF09723.10 KIK37491.1 - 0.17 12.0 0.9 0.26 11.4 0.1 1.7 2 0 0 2 2 2 0 Zinc ribbon domain zf-RVT PF13966.6 KIK37492.1 - 1.6e-05 25.5 1.8 2.7e-05 24.8 1.8 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 KIK37494.1 - 1.1e-06 28.3 0.0 1.3e-06 28.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Daxx PF03344.15 KIK37497.1 - 0.067 13.3 0.0 0.087 12.9 0.0 1.2 1 0 0 1 1 1 0 Daxx N-terminal Rassf1C-interacting domain DUF3980 PF13140.6 KIK37498.1 - 0.017 15.6 0.4 0.022 15.2 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3980) HSF_DNA-bind PF00447.17 KIK37498.1 - 0.087 13.4 0.0 0.43 11.2 0.0 1.9 1 1 0 1 1 1 0 HSF-type DNA-binding POTRA_2 PF08479.11 KIK37500.1 - 3.3e-05 23.6 0.0 3.1 7.7 0.0 3.2 3 0 0 3 3 3 3 POTRA domain, ShlB-type TPR_10 PF13374.6 KIK37500.1 - 0.00047 19.9 11.6 11 6.1 0.3 6.1 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIK37500.1 - 0.0025 18.1 2.1 53 4.5 0.0 4.6 2 2 2 4 4 4 0 Tetratricopeptide repeat SecIII_SopE_N PF05364.14 KIK37500.1 - 0.0098 15.9 5.1 6.8 6.8 0.1 3.5 4 0 0 4 4 4 2 Salmonella type III secretion SopE effector N-terminus Pilin_PilA PF14245.6 KIK37500.1 - 0.087 12.8 0.0 10 6.1 0.0 2.9 1 1 2 3 3 3 0 Type IV pilin PilA Tetrabrachion PF11401.8 KIK37500.1 - 0.93 9.5 3.0 42 4.2 0.0 3.0 3 0 0 3 3 3 0 Tetrabrachion HNH_2 PF13391.6 KIK37504.1 - 1.4e-05 25.1 0.0 2.9e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease zf-CW PF07496.15 KIK37504.1 - 0.19 11.8 0.1 0.44 10.6 0.1 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger DUF3693 PF12472.8 KIK37507.1 - 0.037 13.7 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 Phage related protein p450 PF00067.22 KIK37508.1 - 2.4e-08 33.2 0.0 2.7e-08 33.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KIK37511.1 - 1.8e-37 129.1 65.6 1.4e-34 119.5 65.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KIK37511.1 - 0.00042 19.7 27.9 0.013 14.8 4.8 2.5 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB UPF0016 PF01169.19 KIK37512.1 - 1e-43 147.5 15.2 3.8e-23 81.6 4.3 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 OFeT_1 PF16955.5 KIK37512.1 - 0.0014 18.4 0.9 0.017 14.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron uptake permease, iron-lead transporter LysE PF01810.18 KIK37512.1 - 0.0031 17.0 14.2 0.13 11.8 2.1 3.1 2 2 1 3 3 3 2 LysE type translocator Mntp PF02659.15 KIK37512.1 - 0.0073 16.1 7.8 0.032 14.0 0.1 2.3 2 0 0 2 2 2 1 Putative manganese efflux pump TerC PF03741.16 KIK37512.1 - 0.011 15.5 3.8 0.073 12.7 0.1 2.4 2 1 0 2 2 2 0 Integral membrane protein TerC family DUF3995 PF13160.6 KIK37512.1 - 0.027 14.8 4.4 0.63 10.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) Peptidase_U4 PF03419.13 KIK37512.1 - 0.21 10.8 2.6 0.23 10.7 0.0 1.9 2 0 0 2 2 2 0 Sporulation factor SpoIIGA NnrS PF05940.12 KIK37512.1 - 1.5 8.1 12.4 0.04 13.3 3.7 2.1 2 1 0 2 2 2 0 NnrS protein DUF3667 PF12412.8 KIK37513.1 - 0.054 13.0 0.6 0.14 11.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3667) WD40 PF00400.32 KIK37516.1 - 1.1e-38 130.6 10.2 6.7e-07 29.9 0.3 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37516.1 - 1.8e-12 47.4 0.3 0.036 14.4 0.0 6.1 2 1 6 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK37516.1 - 2.6e-07 29.9 0.1 0.0002 20.4 0.0 3.0 2 2 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK37516.1 - 3e-06 27.3 0.0 0.4 10.5 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK37516.1 - 0.026 13.2 0.1 1.4 7.5 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.12 KIK37516.1 - 0.031 14.2 0.0 11 6.1 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK37516.1 - 0.052 12.9 0.2 0.61 9.4 0.0 2.6 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal CbiM PF01891.16 KIK37518.1 - 0.0036 17.2 4.2 0.0036 17.2 4.2 2.8 2 1 1 3 3 3 2 Cobalt uptake substrate-specific transmembrane region BING4CT PF08149.11 KIK37519.1 - 1.3e-38 130.6 0.4 3.7e-36 122.8 0.0 3.3 4 0 0 4 4 4 1 BING4CT (NUC141) domain WD40 PF00400.32 KIK37519.1 - 0.00013 22.7 0.2 0.03 15.2 0.0 4.1 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF1513 PF07433.11 KIK37519.1 - 0.0063 15.6 0.2 0.024 13.7 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1513) ANAPC4_WD40 PF12894.7 KIK37519.1 - 0.022 15.1 0.0 3.8 7.9 0.0 3.7 3 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KIK37519.1 - 0.088 11.8 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region CDC45 PF02724.14 KIK37519.1 - 7.1 4.8 7.1 9.7 4.3 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein AraC_binding_2 PF14525.6 KIK37522.1 - 0.055 13.1 0.0 0.063 13.0 0.0 1.1 1 0 0 1 1 1 0 AraC-binding-like domain Arylesterase PF01731.20 KIK37525.1 - 0.098 12.9 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Arylesterase Glyoxal_oxid_N PF07250.11 KIK37527.1 - 1.1e-29 103.3 1.3 3.8e-14 52.5 0.0 4.5 4 1 1 5 5 5 3 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KIK37527.1 - 2.2e-24 85.6 0.6 4.7e-24 84.5 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Serglycin PF04360.12 KIK37527.1 - 0.021 14.8 5.8 0.046 13.7 5.8 1.5 1 0 0 1 1 1 0 Serglycin Kelch_4 PF13418.6 KIK37527.1 - 0.037 14.0 2.1 0.29 11.2 0.1 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain UbiA PF01040.18 KIK37529.1 - 1.5e-28 99.8 10.2 2e-28 99.4 10.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Pkinase PF00069.25 KIK37532.1 - 7.1e-42 143.6 0.0 9.4e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK37532.1 - 2e-39 135.5 0.0 2.3e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK37532.1 - 1.4e-05 25.1 0.1 3.5e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KIK37532.1 - 7.2e-05 22.2 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KIK37532.1 - 0.014 14.4 0.1 0.022 13.8 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 KIK37532.1 - 0.016 14.8 0.0 0.034 13.8 0.0 1.5 1 1 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KIK37532.1 - 0.023 13.5 0.2 0.033 12.9 0.2 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KIK37532.1 - 0.029 13.7 0.0 0.04 13.2 0.0 1.1 1 0 0 1 1 1 0 Kinase-like DUF1679 PF07914.11 KIK37532.1 - 0.09 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 KIK37532.1 - 0.22 10.8 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C48 PF02902.19 KIK37533.1 - 0.0034 17.3 3.1 0.0064 16.4 3.1 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain TPR_1 PF00515.28 KIK37535.1 - 0.07 13.0 0.7 7.8 6.5 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Alpha_kinase PF02816.18 KIK37537.1 - 1.9e-05 24.9 0.0 3.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family NACHT PF05729.12 KIK37540.1 - 3.9e-11 43.1 0.1 1.5e-10 41.2 0.1 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK37540.1 - 3.3e-06 27.6 0.1 1.6e-05 25.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KIK37540.1 - 2.5e-05 24.7 0.0 0.0001 22.7 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK37540.1 - 0.00024 21.5 0.1 0.0061 16.9 0.0 2.9 3 0 0 3 3 3 1 RNA helicase AAA_22 PF13401.6 KIK37540.1 - 0.0027 18.0 0.0 0.013 15.7 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 KIK37540.1 - 0.0028 17.7 0.0 0.04 13.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 KIK37540.1 - 0.0033 16.7 1.6 0.093 12.0 0.1 2.3 1 1 0 2 2 2 1 KAP family P-loop domain Zeta_toxin PF06414.12 KIK37540.1 - 0.006 15.9 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 KIK37540.1 - 0.011 16.3 0.0 0.075 13.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.14 KIK37540.1 - 0.013 14.6 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase Sigma54_activ_2 PF14532.6 KIK37540.1 - 0.014 15.5 0.0 6.6 6.8 0.0 3.1 2 1 1 3 3 3 0 Sigma-54 interaction domain NTPase_1 PF03266.15 KIK37540.1 - 0.02 14.8 0.0 0.062 13.2 0.0 1.8 1 1 0 1 1 1 0 NTPase APS_kinase PF01583.20 KIK37540.1 - 0.024 14.6 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DnaB_C PF03796.15 KIK37540.1 - 0.049 13.0 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain RuvB_N PF05496.12 KIK37540.1 - 0.072 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KIK37540.1 - 0.09 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RTX_C PF08339.10 KIK37540.1 - 0.091 12.8 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 RTX C-terminal domain AAA_7 PF12775.7 KIK37540.1 - 0.093 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region 6PF2K PF01591.18 KIK37540.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF2075 PF09848.9 KIK37540.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KIK37540.1 - 0.12 12.7 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIK37540.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RBDV_coat PF06593.11 KIK37543.1 - 0.14 11.6 0.1 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 Raspberry bushy dwarf virus coat protein TAL_FSA PF00923.19 KIK37545.1 - 2e-93 312.9 0.0 2.3e-93 312.7 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase zf-RING_UBOX PF13445.6 KIK37546.1 - 0.0053 16.8 1.3 0.03 14.4 0.4 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIK37546.1 - 0.017 15.4 1.7 0.044 14.1 1.7 1.7 1 1 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 KIK37546.1 - 0.045 13.7 0.2 0.11 12.5 0.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KIK37546.1 - 0.1 12.5 2.1 1.3 8.9 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK37546.1 - 0.12 12.3 0.7 0.33 10.8 0.7 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIK37546.1 - 0.78 9.5 5.1 0.13 12.1 1.1 1.8 2 0 0 2 2 2 0 RING-like zinc finger zf-rbx1 PF12678.7 KIK37546.1 - 0.81 10.0 4.6 2.7 8.4 4.6 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain DNA_ligase_ZBD PF03119.16 KIK37546.1 - 4.8 7.3 9.2 1.2 9.2 0.5 2.7 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain PSS PF03034.15 KIK37547.1 - 4e-115 384.3 10.8 5.3e-115 383.9 10.8 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase Zn_clus PF00172.18 KIK37550.1 - 1.4e-08 34.7 7.2 3e-08 33.6 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.12 KIK37550.1 - 0.024 14.5 0.6 0.69 9.9 0.3 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat TANGO2 PF05742.12 KIK37551.1 - 1.4e-52 179.2 0.0 1.7e-52 179.0 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Actin PF00022.19 KIK37552.1 - 0.003 16.2 0.0 0.003 16.2 0.0 1.0 1 0 0 1 1 1 1 Actin KDZ PF18758.1 KIK37553.1 - 3.7e-69 232.7 0.1 8.1e-69 231.6 0.1 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase GDH_N PF12466.8 KIK37553.1 - 0.12 12.6 0.6 0.99 9.7 0.1 2.4 2 0 0 2 2 2 0 Glutamate dehydrogenase N terminal CKAP2_C PF15297.6 KIK37555.1 - 0.0045 16.1 0.5 0.0082 15.3 0.5 1.4 1 0 0 1 1 1 1 Cytoskeleton-associated protein 2 C-terminus Arg_decarbox_C PF17944.1 KIK37555.1 - 0.12 13.0 1.4 4.6 7.9 0.2 3.1 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension BIRC6 PF12356.8 KIK37555.1 - 0.15 11.5 0.1 0.3 10.5 0.1 1.5 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 His_Phos_2 PF00328.22 KIK37558.1 - 0.087 12.2 0.3 1.1 8.5 0.0 2.1 1 1 1 2 2 2 0 Histidine phosphatase superfamily (branch 2) adh_short PF00106.25 KIK37560.1 - 2.1e-37 128.5 1.5 2.7e-37 128.1 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK37560.1 - 4.2e-21 75.6 0.2 5.7e-21 75.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK37560.1 - 3e-05 24.0 0.1 6.4e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 KR domain 2OG-FeII_Oxy_2 PF13532.6 KIK37563.1 - 8.6e-26 91.3 0.0 1.2e-25 90.9 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily KCH PF16944.5 KIK37564.1 - 0.0063 16.3 1.2 0.0091 15.8 1.2 1.1 1 0 0 1 1 1 1 Fungal potassium channel Spt5_N PF11942.8 KIK37564.1 - 0.034 15.1 24.9 0.033 15.2 3.9 2.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal SDA1 PF05285.12 KIK37564.1 - 0.41 10.0 22.1 0.45 9.9 9.8 2.3 2 0 0 2 2 2 0 SDA1 RXT2_N PF08595.11 KIK37564.1 - 1.2 9.1 15.2 1.6 8.7 5.5 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal YL1 PF05764.13 KIK37564.1 - 2 8.4 24.7 5.4 7.1 6.4 2.4 2 0 0 2 2 2 0 YL1 nuclear protein DUF4637 PF15470.6 KIK37564.1 - 2.2 8.0 22.8 0.69 9.6 9.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Sigma70_ner PF04546.13 KIK37564.1 - 4.6 7.1 19.4 0.17 11.7 3.4 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region NOA36 PF06524.12 KIK37564.1 - 9.2 5.5 30.1 2.8 7.2 14.3 2.2 2 0 0 2 2 2 0 NOA36 protein Rad60-SLD PF11976.8 KIK37566.1 - 5.9e-23 80.5 0.2 8.3e-23 80.0 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KIK37566.1 - 2e-12 46.7 0.0 2.6e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Apolipoprotein PF01442.18 KIK37568.1 - 0.064 13.1 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain CHAT PF12770.7 KIK37570.1 - 3.9e-31 108.5 0.0 7.3e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK37570.1 - 9.9e-11 41.2 3.2 0.049 13.5 0.0 6.7 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIK37570.1 - 6.6e-05 22.6 3.5 1.2 9.1 0.1 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK37570.1 - 0.00017 21.4 1.0 7.4 6.8 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK37570.1 - 0.00078 19.4 4.7 0.95 9.7 0.1 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat MIT PF04212.18 KIK37570.1 - 0.001 19.1 1.1 7.5 6.7 0.1 4.2 3 1 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 KIK37570.1 - 0.011 15.8 1.1 1.1 9.7 0.0 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK37570.1 - 0.075 12.7 0.8 2.6 7.8 0.0 3.7 5 0 0 5 5 5 0 TPR repeat Surp PF01805.20 KIK37570.1 - 0.14 12.2 0.0 0.45 10.5 0.0 1.8 1 0 0 1 1 1 0 Surp module TPR_12 PF13424.6 KIK37570.1 - 0.43 10.9 13.5 19 5.6 0.2 6.4 4 3 2 6 6 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK37570.1 - 5 8.2 15.4 44 5.3 0.0 7.4 7 2 2 9 9 8 0 Tetratricopeptide repeat MFS_1 PF07690.16 KIK37571.1 - 3.7e-25 88.6 36.5 3.8e-25 88.6 35.3 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK37572.1 - 1.4e-114 383.4 13.6 2.4e-114 382.7 13.6 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK37572.1 - 4.8e-23 81.6 55.9 4.7e-18 65.2 27.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Dpoe2NT PF12213.8 KIK37573.1 - 0.004 17.4 0.1 4.1 7.8 0.0 2.9 2 0 0 2 2 2 2 DNA polymerases epsilon N terminal Golgin_A5 PF09787.9 KIK37573.1 - 0.04 13.4 4.4 0.065 12.7 4.4 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 PWI PF01480.17 KIK37574.1 - 1.4e-27 95.8 0.0 2.3e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 PWI domain FR47 PF08445.10 KIK37575.1 - 8.4e-09 35.3 0.0 2.1e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 KIK37575.1 - 2.9e-07 30.5 0.0 4.5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK37575.1 - 3.8e-05 23.9 0.0 6.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK37575.1 - 0.00022 21.6 0.0 0.00037 20.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain VitK2_biosynth PF02621.14 KIK37575.1 - 0.077 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Menaquinone biosynthesis Acetyltransf_CG PF14542.6 KIK37575.1 - 0.18 12.0 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase RNase_P_pop3 PF08228.11 KIK37577.1 - 1.7e-17 63.9 0.0 4e-12 46.5 0.0 2.4 2 1 0 2 2 2 2 RNase P subunit Pop3 Zn_clus PF00172.18 KIK37580.1 - 3.8e-06 26.9 8.7 7.7e-06 25.9 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Surfac_D-trimer PF09006.11 KIK37580.1 - 0.092 12.6 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation PAP1 PF08601.10 KIK37580.1 - 0.27 10.9 7.7 0.36 10.5 7.7 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Herpes_Helicase PF02689.14 KIK37583.1 - 4.7e-07 28.2 0.0 4.7e-07 28.2 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KIK37583.1 - 0.00024 20.9 0.3 0.00069 19.4 0.1 1.9 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain PIF1 PF05970.14 KIK37584.1 - 3.4e-29 102.2 0.0 3.7e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase PIF1 PF05970.14 KIK37585.1 - 1e-36 126.9 0.1 1.2e-36 126.7 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIK37585.1 - 6.1e-06 26.1 0.0 6.7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK37585.1 - 0.00091 19.6 0.0 0.0014 19.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 KIK37585.1 - 0.0033 17.5 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2791 PF10923.8 KIK37585.1 - 0.0077 15.1 0.0 0.0089 14.9 0.0 1.1 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) AAA_7 PF12775.7 KIK37585.1 - 0.03 13.9 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 KIK37585.1 - 0.03 14.8 0.0 0.04 14.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KIK37585.1 - 0.042 13.6 0.0 0.068 12.9 0.0 1.5 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.6 KIK37585.1 - 0.054 13.8 0.0 0.072 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KIK37585.1 - 0.069 13.1 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 NTPase PhoH PF02562.16 KIK37585.1 - 0.08 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 KIK37585.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.22 KIK37585.1 - 0.12 11.5 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 KIK37585.1 - 0.18 11.7 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KIK37585.1 - 0.18 11.8 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Helitron_like_N PF14214.6 KIK37587.1 - 2.1e-60 204.2 0.1 3e-60 203.7 0.1 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3810 PF12725.7 KIK37590.1 - 0.24 10.7 3.4 0.28 10.5 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF5612 PF18462.1 KIK37591.1 - 0.17 11.7 0.0 0.22 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5612) zf-H2C2_5 PF13909.6 KIK37595.1 - 2.6e-09 36.7 13.0 0.0089 15.8 0.6 3.5 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIK37595.1 - 3.2e-09 36.8 17.0 0.0014 19.0 1.4 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK37595.1 - 7.5e-08 32.5 14.3 3.9e-05 23.9 0.4 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK37595.1 - 8.8e-08 32.4 13.9 0.0013 19.4 0.7 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 KIK37595.1 - 0.0075 16.5 11.5 0.45 10.8 5.8 2.6 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.21 KIK37595.1 - 0.064 13.5 8.8 0.13 12.5 1.8 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-met PF12874.7 KIK37595.1 - 0.48 10.9 0.3 0.48 10.9 0.3 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-LITAF-like PF10601.9 KIK37595.1 - 0.76 10.1 8.1 2.4 8.5 8.1 1.9 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain DUF2225 PF09986.9 KIK37595.1 - 0.91 9.2 4.7 0.44 10.2 1.5 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-TRAF PF02176.18 KIK37595.1 - 1.3 9.8 10.7 0.31 11.7 5.8 2.2 1 1 1 2 2 2 0 TRAF-type zinc finger zf-C2H2_9 PF16293.5 KIK37595.1 - 2 8.3 7.8 1 9.3 0.7 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (1 copy) O-FucT PF10250.9 KIK37596.1 - 6.9e-11 42.4 0.0 1.5e-10 41.3 0.0 1.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase FtsX PF02687.21 KIK37597.1 - 7.8 7.0 18.5 0.6 10.6 11.1 2.3 1 1 1 2 2 2 0 FtsX-like permease family DDE_3 PF13358.6 KIK37601.1 - 0.00018 21.3 0.0 0.001 18.8 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_17 PF12728.7 KIK37601.1 - 0.12 12.6 0.2 1.8 8.8 0.1 2.9 2 1 1 3 3 3 0 Helix-turn-helix domain Phage_integrase PF00589.22 KIK37602.1 - 0.046 13.5 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Phage integrase family RNase_H PF00075.24 KIK37603.1 - 1.3e-21 77.3 0.0 1.9e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 RNase H Pkinase PF00069.25 KIK37604.1 - 2.6e-71 240.1 0.0 3.7e-71 239.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK37604.1 - 3.1e-51 174.2 0.0 4.5e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK37604.1 - 2.9e-05 23.0 0.0 6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIK37604.1 - 0.00015 21.2 0.0 0.0068 15.7 0.0 2.3 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.11 KIK37604.1 - 0.0026 17.4 0.0 0.0051 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Haspin_kinase PF12330.8 KIK37604.1 - 0.01 14.8 0.8 0.34 9.8 0.0 2.6 3 0 0 3 3 3 0 Haspin like kinase domain Cation_efflux PF01545.21 KIK37607.1 - 6.5e-18 65.2 12.3 8e-18 64.9 12.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KIK37607.1 - 2.2e-11 43.7 0.5 4.4e-11 42.8 0.5 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter zf-H2C2_2 PF13465.6 KIK37610.1 - 0.0032 17.8 0.5 0.0076 16.6 0.5 1.7 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK37610.1 - 0.035 15.0 6.4 0.27 12.2 4.3 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger FYVE PF01363.21 KIK37610.1 - 0.041 14.0 0.2 0.082 13.1 0.2 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-C2H2 PF00096.26 KIK37610.1 - 0.2 12.1 8.2 0.52 10.9 4.3 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type SPRR2 PF14820.6 KIK37610.1 - 3.9 7.6 10.2 9.3 6.4 10.2 1.6 1 0 0 1 1 1 0 Small proline-rich 2 zf-met PF12874.7 KIK37610.1 - 9.1 6.8 7.4 3.6 8.1 2.0 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type F5_F8_type_C PF00754.25 KIK37612.1 - 0.00099 19.2 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain Y_phosphatase PF00102.27 KIK37613.1 - 4.5e-39 134.4 0.0 8.6e-37 126.9 0.0 2.9 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KIK37613.1 - 0.004 17.3 0.0 0.0071 16.5 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 KIK37613.1 - 0.12 12.2 0.0 0.77 9.6 0.0 2.1 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain ADH_zinc_N PF00107.26 KIK37614.1 - 8.2e-26 90.5 0.0 1.9e-25 89.3 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK37614.1 - 8.5e-17 62.5 0.0 1.7e-16 61.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK37614.1 - 2.5e-05 24.1 0.0 9.1e-05 22.3 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KIK37614.1 - 0.025 14.9 0.1 0.073 13.3 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain DUF2855 PF11017.8 KIK37614.1 - 0.096 12.4 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) His_Phos_2 PF00328.22 KIK37615.1 - 0.00065 19.2 0.2 0.35 10.2 0.0 2.8 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) WD40 PF00400.32 KIK37616.1 - 0.0076 17.1 0.1 0.039 14.8 0.0 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat DPPIV_N PF00930.21 KIK37616.1 - 0.059 12.1 0.0 0.12 11.1 0.0 1.4 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40 PF00400.32 KIK37617.1 - 3.6e-14 52.9 1.5 1.9e-05 25.3 0.4 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.8 KIK37617.1 - 0.0043 15.8 0.2 0.13 10.9 0.0 2.0 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK37617.1 - 0.0045 16.0 0.0 0.0059 15.6 0.0 1.3 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KIK37617.1 - 0.0055 17.0 0.1 13 6.2 0.0 2.9 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KIK37617.1 - 0.017 13.6 0.1 0.019 13.5 0.1 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Phage_30_8 PF06019.11 KIK37617.1 - 0.018 14.9 0.3 0.028 14.3 0.2 1.4 1 1 0 1 1 1 0 Phage GP30.8 protein WD40_like PF17005.5 KIK37617.1 - 0.054 12.8 0.1 0.74 9.1 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain F-box-like PF12937.7 KIK37619.1 - 8.6e-06 25.6 2.3 1.9e-05 24.5 2.3 1.6 1 1 0 1 1 1 1 F-box-like WD40 PF00400.32 KIK37621.1 - 1.6e-10 41.4 0.3 1.9e-05 25.3 0.0 3.5 3 1 0 3 3 3 3 WD domain, G-beta repeat Ret2_MD PF18528.1 KIK37621.1 - 0.04 14.3 0.0 0.088 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA editing 3' terminal uridylyl transferase 2 middle domain ANAPC4_WD40 PF12894.7 KIK37621.1 - 0.091 13.1 0.0 0.36 11.1 0.0 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK37624.1 - 1.4e-35 120.7 15.6 2.8e-07 31.1 0.4 8.3 8 0 0 8 8 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37624.1 - 5.1e-10 39.5 0.1 0.45 10.8 0.0 5.5 3 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 KIK37624.1 - 1.5e-09 38.3 2.7 2.1e-07 31.4 0.1 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ge1_WD40 PF16529.5 KIK37624.1 - 1.8e-06 27.2 0.0 0.00034 19.7 0.0 2.8 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_2 PF07719.17 KIK37624.1 - 2.4e-05 24.1 11.4 0.58 10.4 0.3 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK37624.1 - 0.00083 19.1 6.7 0.42 10.5 0.1 6.2 8 0 0 8 8 8 1 Tetratricopeptide repeat BTAD PF03704.17 KIK37624.1 - 0.042 14.3 4.0 2.5 8.5 0.1 3.4 2 1 0 2 2 2 0 Bacterial transcriptional activator domain TPR_16 PF13432.6 KIK37624.1 - 0.044 14.4 9.3 0.26 11.9 0.7 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK37624.1 - 0.046 13.4 1.8 0.17 11.6 0.3 2.7 3 0 0 3 3 3 0 TPR repeat DUF5628 PF18621.1 KIK37624.1 - 0.064 13.7 0.2 16 6.0 0.0 2.8 1 1 0 2 2 2 0 Family of unknown function (DUF5628) TPR_7 PF13176.6 KIK37624.1 - 0.14 12.2 3.5 15 5.9 0.1 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat MIT PF04212.18 KIK37624.1 - 0.3 11.2 1.2 31 4.7 0.1 2.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 KIK37624.1 - 0.97 10.0 13.2 1.9 9.0 0.6 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK37624.1 - 1.3 10.0 13.3 12 7.0 0.4 5.4 6 1 1 7 7 5 0 Tetratricopeptide repeat RT_RNaseH_2 PF17919.1 KIK37625.1 - 8.4e-10 38.6 0.0 1e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Cwf_Cwc_15 PF04889.12 KIK37626.1 - 0.98 9.1 12.7 2.8 7.6 12.7 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4337 PF14235.6 KIK37626.1 - 9.6 6.3 13.4 18 5.4 13.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Zn_clus PF00172.18 KIK37630.1 - 0.016 15.3 12.3 0.41 10.8 3.1 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RVP_2 PF08284.11 KIK37631.1 - 8.6e-07 28.8 0.6 1.1e-06 28.4 0.6 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KIK37631.1 - 0.0064 17.1 0.0 0.0087 16.7 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.8 KIK37631.1 - 0.024 14.2 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 Ty3 transposon peptidase CxC5 PF18718.1 KIK37635.1 - 1.2e-07 31.8 0.7 1.2e-07 31.8 0.7 1.0 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases Pex2_Pex12 PF04757.14 KIK37641.1 - 8.9e-37 126.8 3.5 1.2e-36 126.4 3.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 KIK37641.1 - 0.0016 18.3 2.0 0.0016 18.3 2.0 2.1 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIK37641.1 - 0.0038 17.2 1.2 0.0038 17.2 1.2 2.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIK37641.1 - 0.0064 16.3 2.8 0.044 13.7 2.9 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK37641.1 - 0.015 15.1 1.9 0.031 14.1 0.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK37641.1 - 0.032 14.1 0.9 0.032 14.1 0.9 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KIK37641.1 - 0.068 13.3 3.3 0.34 11.1 3.7 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KIK37641.1 - 0.6 10.5 6.0 0.85 10.0 2.0 2.5 2 1 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.6 KIK37641.1 - 0.8 9.6 10.0 2.6 8.0 6.1 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) tRNA-synt_2d PF01409.20 KIK37642.1 - 1.3e-83 280.3 0.0 5.4e-83 278.2 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KIK37642.1 - 4.2e-15 55.8 1.1 1e-14 54.6 0.2 2.2 3 0 0 3 3 3 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KIK37642.1 - 8.7e-09 35.1 0.0 0.00017 21.1 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 KIK37642.1 - 0.00019 20.6 0.5 0.019 14.0 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 KIK37642.1 - 0.004 17.1 0.0 0.008 16.1 0.0 1.5 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2b PF00587.25 KIK37642.1 - 0.0077 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ThrE PF06738.12 KIK37643.1 - 2.1e-46 158.3 4.0 2.1e-46 158.3 4.0 2.4 2 1 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KIK37643.1 - 5.1e-06 26.7 24.3 1.1e-05 25.5 7.9 2.9 2 1 0 2 2 2 2 Threonine/Serine exporter, ThrE DUF4574 PF15141.6 KIK37643.1 - 0.15 12.0 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Acetyltransf_1 PF00583.25 KIK37644.1 - 2.4e-10 40.7 0.0 5.1e-10 39.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK37644.1 - 3.1e-08 33.9 0.0 3.8e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIK37644.1 - 9.9e-07 28.7 0.0 2.4e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK37644.1 - 1.2e-06 28.4 0.0 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KIK37644.1 - 4.9e-05 24.0 0.1 0.022 15.4 0.0 2.2 1 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIK37644.1 - 0.002 18.2 0.0 0.0034 17.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KIK37644.1 - 0.0036 17.4 0.0 0.011 15.8 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIK37644.1 - 0.011 15.9 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Nudix_hydro PF18290.1 KIK37644.1 - 0.086 12.9 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Nudix hydrolase domain Acetyltransf_8 PF13523.6 KIK37644.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Phage_integrase PF00589.22 KIK37646.1 - 0.00033 20.5 0.0 0.00048 20.0 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 KIK37646.1 - 0.019 15.2 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 KIK37646.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.6 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain tRNA_synthFbeta PF17759.1 KIK37649.1 - 4e-47 160.4 0.0 5.6e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KIK37649.1 - 8.4e-30 102.8 0.0 1.6e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KIK37649.1 - 2.1e-24 86.2 0.1 3.6e-24 85.4 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KIK37649.1 - 2.2e-12 47.1 0.0 7.2e-10 39.0 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetase B5 domain Endonuc-dimeris PF09124.10 KIK37649.1 - 0.038 14.1 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 T4 recombination endonuclease VII, dimerisation DUF2370 PF10176.9 KIK37650.1 - 1.7e-64 217.6 0.0 2.3e-64 217.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) MscS_TM PF12794.7 KIK37651.1 - 0.092 11.6 1.5 0.15 10.9 1.5 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Diphthami_syn_2 PF01902.17 KIK37653.1 - 3.5e-39 134.6 0.0 2.5e-37 128.5 0.0 2.2 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KIK37653.1 - 4.3e-20 71.9 0.0 1.5e-11 44.3 0.0 2.5 2 0 0 2 2 2 2 Endoribonuclease L-PSP MFS_2 PF13347.6 KIK37654.1 - 8.7e-08 31.1 7.1 8.7e-08 31.1 7.1 3.4 2 2 0 2 2 2 2 MFS/sugar transport protein Ank_2 PF12796.7 KIK37655.1 - 4.6e-22 78.4 0.0 3e-15 56.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK37655.1 - 8.5e-21 74.1 0.3 1.3e-13 51.2 0.1 4.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIK37655.1 - 1e-18 67.1 0.3 9.2e-10 38.6 0.1 3.6 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK37655.1 - 1.6e-14 52.6 0.2 0.00013 22.1 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KIK37655.1 - 4.7e-13 48.9 0.1 1.1e-05 25.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Zn_ribbon_SprT PF17283.2 KIK37656.1 - 0.26 11.2 3.1 8.3 6.4 0.4 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain AAA_12 PF13087.6 KIK37658.1 - 1.3e-44 152.2 0.0 2.6e-44 151.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK37658.1 - 3e-28 99.3 0.0 5.1e-13 49.4 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KIK37658.1 - 6.7e-13 48.8 0.0 1.9e-12 47.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK37658.1 - 8.8e-11 42.3 0.0 9.3e-10 39.0 0.0 2.6 2 1 0 2 2 1 1 AAA domain zf-met PF12874.7 KIK37658.1 - 1.8e-09 37.7 16.1 0.00018 21.8 2.1 3.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type UvrD-helicase PF00580.21 KIK37658.1 - 2.1e-07 30.8 0.0 0.00032 20.3 0.0 2.3 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain zf-C2H2_jaz PF12171.8 KIK37658.1 - 4.2e-05 23.7 13.1 0.022 15.0 1.4 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding ResIII PF04851.15 KIK37658.1 - 5.9e-05 23.1 0.0 0.00012 22.1 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KIK37658.1 - 9.3e-05 22.0 0.0 0.34 10.3 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_22 PF13401.6 KIK37658.1 - 0.00093 19.5 0.0 0.0028 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF3449 PF11931.8 KIK37658.1 - 0.0011 18.8 0.4 0.0011 18.8 0.4 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF3449) Helicase_RecD PF05127.14 KIK37658.1 - 0.0073 16.2 0.0 0.025 14.4 0.0 1.9 2 0 0 2 2 2 1 Helicase Viral_helicase1 PF01443.18 KIK37658.1 - 0.0091 15.8 0.1 24 4.6 0.0 3.4 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KIK37658.1 - 0.028 14.8 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain zf-C2H2_2 PF12756.7 KIK37658.1 - 0.043 14.2 8.8 0.12 12.8 0.8 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) AAA_7 PF12775.7 KIK37658.1 - 0.049 13.1 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region UvrD_C_2 PF13538.6 KIK37658.1 - 0.061 13.2 0.3 0.37 10.6 0.3 2.3 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.29 KIK37658.1 - 0.086 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-C2H2_4 PF13894.6 KIK37658.1 - 0.73 10.8 5.1 2.4 9.2 0.2 3.3 2 0 0 2 2 2 0 C2H2-type zinc finger Mg_trans_NIPA PF05653.14 KIK37659.1 - 1.3e-98 329.8 13.7 1.5e-98 329.6 13.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA PEMT PF04191.13 KIK37659.1 - 0.38 11.2 0.1 0.38 11.2 0.1 3.1 3 1 0 3 3 3 0 Phospholipid methyltransferase EamA PF00892.20 KIK37659.1 - 0.74 10.0 30.6 0.032 14.4 5.4 3.2 2 1 1 3 3 3 0 EamA-like transporter family DUF5518 PF17647.1 KIK37659.1 - 3.1 8.0 24.9 1.4 9.1 6.2 3.5 3 1 0 3 3 3 0 Family of unknown function (DUF5518) DUF1129 PF06570.11 KIK37659.1 - 5.8 6.4 9.2 1.6 8.2 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Creatinase_N_2 PF16189.5 KIK37660.1 - 1.9e-47 161.4 0.0 2.7e-46 157.6 0.0 2.6 4 0 0 4 4 4 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KIK37660.1 - 2.5e-45 154.8 0.0 3.6e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KIK37660.1 - 2.8e-25 88.1 0.1 7.7e-25 86.7 0.1 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KIK37660.1 - 2.9e-22 79.7 0.0 6.1e-17 62.5 0.0 2.7 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain Pkinase PF00069.25 KIK37663.1 - 7.1e-21 74.8 0.0 9.3e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK37663.1 - 7.9e-06 25.3 0.0 1.1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase AA_kinase PF00696.28 KIK37664.1 - 1.9e-38 132.5 0.0 6.2e-38 130.8 0.0 1.8 1 1 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 KIK37664.1 - 1.7e-08 34.1 2.0 3.4e-06 26.8 0.1 2.8 3 0 0 3 3 3 2 ACT domain ACT PF01842.25 KIK37664.1 - 1.8e-07 30.8 0.4 0.0067 16.2 0.1 2.7 2 0 0 2 2 2 2 ACT domain G-alpha PF00503.20 KIK37667.1 - 2.3e-131 438.2 0.0 2.7e-131 438.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK37667.1 - 9.2e-09 35.0 0.0 9.4e-06 25.2 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family TniB PF05621.11 KIK37667.1 - 0.0027 17.1 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_29 PF13555.6 KIK37667.1 - 0.011 15.4 0.2 0.039 13.7 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KIK37667.1 - 0.077 13.5 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DAP3 PF10236.9 KIK37667.1 - 0.11 11.6 0.1 0.38 9.9 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Roc PF08477.13 KIK37667.1 - 0.12 12.6 0.0 4.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF1270 PF06900.11 KIK37668.1 - 0.0023 18.3 0.6 0.0037 17.6 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1270) SWI-SNF_Ssr4 PF08549.10 KIK37670.1 - 0.78 8.3 7.8 0.9 8.1 7.0 1.4 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) Exo_endo_phos PF03372.23 KIK37671.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 KIK37672.1 - 8.7e-08 31.9 0.0 1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Succ_CoA_lig PF13607.6 KIK37676.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain DUF1543 PF07566.12 KIK37676.1 - 0.044 13.5 0.6 0.13 12.0 0.6 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1543) FeS_assembly_P PF01883.19 KIK37685.1 - 1.2e-11 44.6 0.0 2.1e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein Hep_core_N PF08290.11 KIK37686.1 - 0.083 12.9 2.2 0.18 11.8 2.2 1.5 1 0 0 1 1 1 0 Hepatitis core protein, putative zinc finger Cullin_binding PF03556.15 KIK37687.1 - 8.5e-26 90.8 0.1 1.2e-25 90.3 0.1 1.2 1 0 0 1 1 1 1 Cullin binding DUF520 PF04461.13 KIK37688.1 - 0.015 15.4 0.1 0.022 14.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF520) zf-RING_4 PF14570.6 KIK37689.1 - 1.7e-21 75.7 11.5 2.9e-21 75.0 11.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KIK37689.1 - 3.1e-05 23.7 8.4 5.7e-05 22.9 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK37689.1 - 0.0028 17.5 8.7 0.13 12.1 9.2 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 RRM_1 PF00076.22 KIK37689.1 - 0.014 15.2 0.0 0.037 13.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.11 KIK37689.1 - 0.058 13.3 3.6 0.12 12.3 3.6 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) ERM PF00769.19 KIK37689.1 - 0.079 12.8 43.9 0.027 14.3 30.7 3.5 3 0 0 3 3 3 0 Ezrin/radixin/moesin family zf-UDP PF14569.6 KIK37689.1 - 0.091 12.9 2.4 0.21 11.7 2.4 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_2 PF13639.6 KIK37689.1 - 0.092 13.1 11.6 0.18 12.2 11.6 1.5 1 0 0 1 1 1 0 Ring finger domain DUF1272 PF06906.11 KIK37689.1 - 1.6 8.9 7.3 3.4 7.8 7.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_UBOX PF13445.6 KIK37689.1 - 1.7 8.7 7.4 3.1 7.9 6.1 2.1 1 1 1 2 2 2 0 RING-type zinc-finger DEAD PF00270.29 KIK37691.1 - 2e-42 144.9 0.0 3.2e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK37691.1 - 4.3e-24 85.0 0.0 2.4e-20 72.9 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 KIK37691.1 - 1.4e-08 35.0 0.0 2.1e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KIK37691.1 - 3.6e-05 23.1 0.0 6.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.6 KIK37691.1 - 0.00067 19.4 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK37691.1 - 0.00079 19.8 0.7 0.0094 16.3 0.6 2.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK37691.1 - 0.017 15.4 2.1 0.34 11.2 2.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KIK37691.1 - 0.019 14.8 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain dsDNA_bind PF01984.20 KIK37692.1 - 1.8e-27 95.8 8.6 2e-27 95.7 8.6 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain PCI PF01399.27 KIK37692.1 - 0.045 14.3 0.1 0.057 13.9 0.1 1.3 1 0 0 1 1 1 0 PCI domain UCH_1 PF13423.6 KIK37693.1 - 2.2e-87 293.7 0.0 2.9e-87 293.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KIK37693.1 - 1.3e-20 74.6 0.0 2.6e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 KIK37693.1 - 1.9e-05 24.3 0.0 6.2e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UDG PF03167.19 KIK37694.1 - 9e-19 68.0 0.0 1.4e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Sas10_Utp3 PF04000.15 KIK37695.1 - 2.9e-15 56.7 0.2 7e-15 55.4 0.2 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family MUG113 PF13455.6 KIK37696.1 - 6e-14 52.5 0.0 1.9e-13 50.9 0.0 1.8 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KIK37696.1 - 6.2e-10 39.5 0.1 1.2e-08 35.4 0.0 2.7 3 1 0 3 3 3 1 T5orf172 domain Parvo_coat PF00740.18 KIK37696.1 - 0.0056 15.4 0.1 0.0065 15.2 0.1 1.1 1 0 0 1 1 1 1 Parvovirus coat protein VP2 AAA_32 PF13654.6 KIK37696.1 - 0.013 14.4 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain BBIP10 PF14777.6 KIK37700.1 - 0.2 11.2 0.4 0.42 10.2 0.0 1.7 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 Trp_syntA PF00290.20 KIK37701.1 - 7.2e-83 277.4 0.2 1e-82 276.9 0.2 1.1 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KIK37701.1 - 2.5e-44 151.9 0.1 4.1e-44 151.2 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 KIK37701.1 - 0.0007 19.1 0.0 0.0016 17.9 0.0 1.6 1 0 0 1 1 1 1 Histidine biosynthesis protein PA PF02225.22 KIK37701.1 - 0.032 14.3 0.3 4 7.5 0.0 2.9 3 0 0 3 3 3 0 PA domain RNase_P_p30 PF01876.16 KIK37703.1 - 2.1e-37 128.7 0.0 3.1e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 adh_short PF00106.25 KIK37704.1 - 5e-46 156.6 1.0 6.1e-46 156.3 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK37704.1 - 1.6e-35 122.7 0.1 2.1e-35 122.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK37704.1 - 4e-09 36.6 0.3 7.6e-09 35.7 0.3 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KIK37704.1 - 5.5e-06 26.0 0.0 8.4e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KIK37704.1 - 2.2e-05 24.0 0.1 3.4e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK37704.1 - 0.00064 19.2 0.0 0.00087 18.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KIK37704.1 - 0.014 14.5 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain AIRS PF00586.24 KIK37704.1 - 0.038 14.6 0.1 0.061 14.0 0.1 1.5 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain DUF1707 PF08044.11 KIK37704.1 - 0.086 12.9 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) adh_short PF00106.25 KIK37705.1 - 1.8e-46 158.1 0.2 2.2e-46 157.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK37705.1 - 6.3e-35 120.8 0.0 8.2e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK37705.1 - 2.8e-09 37.2 0.0 5.7e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KIK37705.1 - 1.4e-05 24.7 0.0 2.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KIK37705.1 - 4.8e-05 22.9 0.0 6.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK37705.1 - 0.0027 17.2 0.0 0.0038 16.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KIK37705.1 - 0.021 13.9 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DFP PF04127.15 KIK37705.1 - 0.042 13.7 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein A_deaminase PF00962.22 KIK37706.1 - 5.5e-29 101.5 0.0 1.2e-26 93.8 0.0 2.1 2 0 0 2 2 2 2 Adenosine/AMP deaminase MPS2 PF17060.5 KIK37707.1 - 0.0074 15.6 1.2 0.0074 15.6 1.2 2.2 1 1 0 2 2 2 1 Monopolar spindle protein 2 Spc7 PF08317.11 KIK37707.1 - 0.011 14.6 11.3 0.16 10.9 1.6 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 KIK37707.1 - 0.06 12.7 6.8 0.18 11.1 6.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 KIK37707.1 - 0.79 10.0 7.7 4.5 7.6 2.5 2.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Tup_N PF08581.10 KIK37707.1 - 0.82 10.0 14.5 0.25 11.7 3.8 3.0 3 0 0 3 3 3 0 Tup N-terminal SHE3 PF17078.5 KIK37707.1 - 1.3 8.7 10.1 2.2 7.9 1.2 2.4 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 FAM76 PF16046.5 KIK37707.1 - 1.9 7.8 14.3 0.15 11.3 7.0 2.2 1 1 1 2 2 2 0 FAM76 protein UPF0242 PF06785.11 KIK37707.1 - 2.3 8.3 10.0 6.5 6.8 1.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Herpes_UL25 PF01499.16 KIK37707.1 - 3.7 5.9 8.0 0.18 10.3 0.7 2.0 1 1 1 2 2 2 0 Herpesvirus UL25 family CSRNP_N PF16019.5 KIK37708.1 - 2.2 8.2 12.9 0.44 10.4 7.6 2.0 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus A_deaminase PF00962.22 KIK37710.1 - 3.1e-26 92.5 0.1 7.9e-25 87.9 0.0 2.2 2 0 0 2 2 2 2 Adenosine/AMP deaminase Ribosomal_L7Ae PF01248.26 KIK37711.1 - 1e-24 86.1 0.0 1.3e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KIK37711.1 - 0.00014 21.9 0.0 0.00017 21.7 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KIK37711.1 - 0.0003 20.6 0.0 0.00046 20.0 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain KH_1 PF00013.29 KIK37712.1 - 4.1e-43 145.1 8.1 1.6e-15 56.7 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KIK37712.1 - 1.2e-14 53.9 6.5 4.3e-05 23.3 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KIK37712.1 - 1.4e-05 24.8 2.6 0.11 12.4 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 KIK37712.1 - 0.00035 20.6 5.2 0.94 9.6 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain Macoilin PF09726.9 KIK37712.1 - 1.4 7.4 7.9 1.7 7.1 7.9 1.1 1 0 0 1 1 1 0 Macoilin family TFIIF_alpha PF05793.12 KIK37712.1 - 4.8 5.7 14.5 6.7 5.2 14.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Brix PF04427.18 KIK37713.1 - 1.2e-37 129.9 0.1 1.6e-37 129.5 0.1 1.2 1 0 0 1 1 1 1 Brix domain CPDase PF07823.11 KIK37716.1 - 1.3e-14 54.4 1.5 8.7e-14 51.7 1.5 2.3 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 KIK37716.1 - 2.8e-11 43.6 0.0 3.6e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KIK37716.1 - 3.6e-05 23.9 0.1 0.018 15.2 0.0 2.2 2 0 0 2 2 2 2 LigT like Phosphoesterase DUF1776 PF08643.10 KIK37717.1 - 8.9e-13 48.3 0.0 1.2e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) PRIMA1 PF16101.5 KIK37717.1 - 0.0028 17.7 2.8 0.0056 16.7 2.8 1.4 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 DUF883 PF05957.13 KIK37717.1 - 0.0059 17.2 0.0 0.083 13.5 0.1 2.3 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) CAP_N PF01213.19 KIK37717.1 - 9.3 5.6 5.6 18 4.7 5.6 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal WD40 PF00400.32 KIK37719.1 - 1.6e-41 139.5 8.1 6.6e-07 29.9 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37719.1 - 1.1e-11 44.8 0.3 0.19 12.0 0.0 5.5 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK37719.1 - 0.00073 19.5 0.1 3 7.7 0.0 3.7 1 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK37719.1 - 0.0064 15.5 5.8 1 8.2 0.1 4.1 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK37719.1 - 0.049 13.6 0.0 29 4.8 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK37719.1 - 0.17 11.2 0.0 6.3 6.0 0.0 2.6 3 0 0 3 3 3 0 WD40-like domain TPR_2 PF07719.17 KIK37720.1 - 0.00013 21.8 0.3 0.81 9.9 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK37720.1 - 0.0024 17.6 0.3 4.8 7.2 0.1 4.0 5 0 0 5 5 5 2 Tetratricopeptide repeat DUF3856 PF12968.7 KIK37720.1 - 0.014 15.4 0.1 6.6 6.8 0.0 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) ATP-synt_ab PF00006.25 KIK37721.1 - 7.5e-15 55.2 0.1 1.3e-14 54.3 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 KIK37721.1 - 0.036 13.9 0.2 0.44 10.4 0.0 2.2 2 0 0 2 2 2 0 T3SS EscN ATPase C-terminal domain Med2 PF11214.8 KIK37721.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.7 1 1 0 1 1 1 0 Mediator complex subunit 2 IL31 PF15209.6 KIK37722.1 - 0.072 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Interleukin 31 N_NLPC_P60 PF12912.7 KIK37722.1 - 0.078 13.3 0.0 0.29 11.5 0.0 1.9 1 1 0 1 1 1 0 NLPC_P60 stabilising domain, N term MFS_1 PF07690.16 KIK37724.1 - 3.6e-17 62.3 53.8 4.7e-13 48.8 36.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4449 PF14613.6 KIK37725.1 - 1e-31 110.2 7.7 1e-31 110.2 7.7 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) YtxH PF12732.7 KIK37725.1 - 0.57 10.8 6.3 0.16 12.5 1.4 2.7 2 0 0 2 2 2 0 YtxH-like protein LEA_4 PF02987.16 KIK37725.1 - 8.2 6.6 13.3 0.55 10.4 5.7 2.5 2 0 0 2 2 2 0 Late embryogenesis abundant protein Mu-like_Com PF10122.9 KIK37728.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 Mu-like prophage protein Com RTX PF02382.15 KIK37729.1 - 0.39 10.4 5.7 0.22 11.2 1.5 2.0 1 1 1 2 2 2 0 N-terminal domain in RTX protein DUF1635 PF07795.11 KIK37732.1 - 0.087 12.7 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Death PF00531.22 KIK37735.1 - 0.2 11.8 0.2 0.65 10.2 0.1 1.8 2 0 0 2 2 2 0 Death domain CM_2 PF01817.21 KIK37738.1 - 3.4e-11 43.3 0.0 4.2e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Chorismate mutase type II ABC_tran PF00005.27 KIK37739.1 - 6.3e-28 98.0 0.0 6.3e-17 62.4 0.0 3.3 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 KIK37739.1 - 1.1e-07 31.9 3.5 0.025 14.4 0.9 3.6 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KIK37739.1 - 2.1e-05 24.7 0.0 0.017 15.4 0.0 2.8 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 KIK37739.1 - 0.0041 16.6 0.0 0.63 9.4 0.0 2.4 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIK37739.1 - 0.015 15.0 0.1 0.044 13.5 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ploopntkinase1 PF18748.1 KIK37739.1 - 0.039 13.5 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 NACHT PF05729.12 KIK37739.1 - 0.042 13.8 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF3584 PF12128.8 KIK37739.1 - 0.053 11.0 0.1 0.077 10.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BTB PF00651.31 KIK37740.1 - 0.047 13.9 0.0 16 5.8 0.0 2.3 2 0 0 2 2 2 0 BTB/POZ domain DUF4731 PF15875.5 KIK37741.1 - 0.013 15.6 0.1 0.019 15.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4731) YwcE PF17368.2 KIK37741.1 - 0.039 14.6 0.1 0.048 14.3 0.1 1.3 1 1 0 1 1 1 0 Spore morphogenesis and germination YwcE TUG-UBL1 PF11470.8 KIK37742.1 - 0.0071 16.5 0.0 0.03 14.5 0.0 1.9 1 1 0 1 1 1 1 TUG ubiquitin-like domain EF-hand_6 PF13405.6 KIK37744.1 - 2.9e-23 79.8 0.3 3.6e-08 32.7 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 KIK37744.1 - 3.2e-22 76.4 2.1 3.1e-07 29.5 0.1 4.9 4 1 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KIK37744.1 - 2e-20 73.0 0.7 2.1e-08 34.5 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KIK37744.1 - 4.4e-17 60.7 2.0 0.00056 19.3 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KIK37744.1 - 2.4e-11 43.3 5.9 0.00032 20.5 0.1 4.7 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 KIK37744.1 - 0.0094 16.3 0.1 2.7 8.4 0.0 3.2 3 1 0 3 3 3 1 EF-hand domain WD40 PF00400.32 KIK37746.1 - 2.5e-17 62.9 16.5 0.00029 21.6 0.0 6.4 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37746.1 - 1.7e-16 60.3 1.5 8.1e-06 26.1 0.2 4.4 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK37746.1 - 5.1e-05 23.2 0.5 0.018 14.9 0.2 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KIK37746.1 - 0.021 14.2 0.0 0.7 9.2 0.0 2.7 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal MMR_HSR1 PF01926.23 KIK37747.1 - 3.4e-05 23.9 0.0 4.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KIK37747.1 - 0.00023 20.7 0.0 0.00048 19.6 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIK37747.1 - 0.002 17.7 0.0 0.65 9.5 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Roc PF08477.13 KIK37747.1 - 0.0023 18.2 0.0 0.0063 16.7 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KIK37747.1 - 0.0066 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein Septin PF00735.18 KIK37747.1 - 0.018 14.3 0.0 1.3 8.2 0.0 2.0 2 0 0 2 2 2 0 Septin G-alpha PF00503.20 KIK37747.1 - 0.02 14.0 0.1 0.16 11.1 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit RsgA_GTPase PF03193.16 KIK37747.1 - 0.032 14.1 0.0 7.8 6.4 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 KIK37747.1 - 0.044 13.5 0.0 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 KIK37747.1 - 0.091 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B ATP-synt_ab PF00006.25 KIK37747.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ATPase_2 PF01637.18 KIK37747.1 - 0.15 12.0 0.0 0.64 9.9 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Bromodomain PF00439.25 KIK37749.1 - 2.2e-20 72.5 0.6 6.6e-20 71.0 0.4 1.9 1 1 1 2 2 2 1 Bromodomain Bromo_TP PF07524.13 KIK37749.1 - 7.7e-05 22.6 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated NACHT PF05729.12 KIK37750.1 - 5.9e-10 39.3 0.1 1.3e-09 38.2 0.1 1.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK37750.1 - 2.7e-08 34.4 0.0 3.9e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK37750.1 - 0.0019 18.6 0.1 0.016 15.7 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KIK37750.1 - 0.01 16.4 0.1 0.03 14.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIK37750.1 - 0.028 14.8 0.0 0.049 14.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 KIK37750.1 - 0.031 13.4 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 KIK37750.1 - 0.036 14.2 0.0 0.051 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK37750.1 - 0.047 14.0 0.0 0.12 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 KIK37750.1 - 0.13 11.4 0.0 0.45 9.6 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 APS_kinase PF01583.20 KIK37750.1 - 0.13 12.2 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase Dimer_Tnp_hAT PF05699.14 KIK37752.1 - 7.8e-08 32.0 0.0 9.4e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Nkap_C PF06047.11 KIK37754.1 - 5.1e-42 142.1 2.7 5.1e-42 142.1 2.7 2.2 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain SAPS PF04499.15 KIK37754.1 - 0.57 8.9 6.4 0.8 8.4 6.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FKBP_C PF00254.28 KIK37755.1 - 5.1e-34 116.5 0.0 6.1e-34 116.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ribosomal_L39 PF00832.20 KIK37756.1 - 2.6e-23 81.4 9.0 3e-23 81.2 9.0 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Nmad3 PF18754.1 KIK37756.1 - 0.033 13.8 0.3 0.034 13.7 0.3 1.0 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 CHD5 PF04420.14 KIK37757.1 - 1.4e-58 197.3 3.9 1.6e-58 197.0 3.9 1.0 1 0 0 1 1 1 1 CHD5-like protein Melittin PF01372.17 KIK37757.1 - 0.02 14.8 1.2 0.9 9.6 0.2 2.6 2 0 0 2 2 2 0 Melittin T3SS_needle_E PF08988.10 KIK37757.1 - 0.16 12.1 1.0 0.23 11.6 1.0 1.2 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle Malate_synthase PF01274.22 KIK37758.1 - 2.9e-203 675.9 0.0 3.4e-203 675.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase OsmC PF02566.19 KIK37759.1 - 5.5e-13 49.3 0.0 1.2e-12 48.2 0.0 1.5 2 0 0 2 2 2 1 OsmC-like protein MMS1_N PF10433.9 KIK37760.1 - 1.1e-159 532.2 0.0 1.5e-159 531.7 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KIK37760.1 - 4.7e-95 318.6 0.0 5.2e-94 315.2 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region MFS_1 PF07690.16 KIK37761.1 - 1.1e-32 113.4 34.5 1.6e-32 112.8 34.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily YrhC PF14143.6 KIK37761.1 - 0.12 12.5 1.2 2 8.5 0.1 3.3 3 0 0 3 3 3 0 YrhC-like protein UNC-93 PF05978.16 KIK37762.1 - 1.3e-15 57.4 9.4 1.3e-15 57.4 9.4 2.8 3 1 1 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KIK37762.1 - 1.7e-13 50.2 36.3 1.7e-13 50.2 36.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Topoisom_bac PF01131.20 KIK37763.1 - 4.2e-110 368.6 0.0 5.2e-110 368.3 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.12 KIK37763.1 - 3.8e-25 87.7 20.8 3.5e-13 49.4 7.3 2.9 2 0 0 2 2 2 2 GRF zinc finger Toprim PF01751.22 KIK37763.1 - 7.3e-20 71.1 0.0 6.1e-19 68.2 0.0 2.3 2 0 0 2 2 2 1 Toprim domain zf-CCHC PF00098.23 KIK37763.1 - 8.3e-12 44.6 10.4 1.4e-05 24.9 1.3 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 KIK37763.1 - 7.2e-09 35.5 4.2 1.8e-05 24.6 0.5 2.8 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 KIK37763.1 - 0.00014 21.6 7.4 0.036 13.9 0.9 2.5 2 0 0 2 2 2 2 Zinc knuckle eIF3g PF12353.8 KIK37763.1 - 0.035 14.5 8.6 0.92 9.9 1.0 2.8 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_5 PF14787.6 KIK37763.1 - 0.2 11.4 14.8 0.26 11.0 0.6 2.8 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger UTP25 PF06862.12 KIK37766.1 - 3.8e-164 546.9 0.1 4.7e-164 546.6 0.1 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 F-box_4 PF15966.5 KIK37767.1 - 0.11 12.4 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 F-box Plavaka PF18759.1 KIK37768.1 - 5.9e-26 91.5 0.0 1.5e-25 90.1 0.0 1.7 1 1 0 1 1 1 1 Plavaka transposase SpdB PF05122.13 KIK37769.1 - 0.09 12.9 1.0 0.15 12.2 0.2 1.8 2 0 0 2 2 2 0 Mobile element transfer protein Fez1 PF06818.15 KIK37770.1 - 0.013 16.0 3.2 0.016 15.7 3.2 1.1 1 0 0 1 1 1 0 Fez1 Na_Ca_ex_C PF16494.5 KIK37770.1 - 0.049 14.1 1.2 0.07 13.6 1.2 1.3 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain DUF4432 PF14486.6 KIK37771.1 - 0.094 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) WD40 PF00400.32 KIK37773.1 - 9.1e-36 121.3 13.3 2.6e-07 31.2 0.0 8.4 7 1 1 8 8 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37773.1 - 2.1e-09 37.6 0.1 0.99 9.8 0.1 6.2 2 1 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 KIK37773.1 - 2.9e-08 34.2 3.9 9.7e-07 29.2 0.3 2.8 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Ge1_WD40 PF16529.5 KIK37773.1 - 2.5e-05 23.4 0.0 0.057 12.4 0.0 2.9 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_14 PF13428.6 KIK37773.1 - 0.00015 22.3 8.1 7.1 7.7 0.0 6.3 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK37773.1 - 0.00024 21.0 6.6 0.92 9.8 0.3 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK37773.1 - 0.00034 20.3 3.7 1.9 8.4 0.1 5.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK37773.1 - 0.0021 17.9 4.6 23 5.3 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK37773.1 - 0.024 14.3 1.2 0.13 12.0 0.1 2.8 2 1 1 3 3 3 0 TPR repeat TPR_12 PF13424.6 KIK37773.1 - 0.029 14.7 10.9 6.7 7.1 0.8 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat PD40 PF07676.12 KIK37773.1 - 0.11 12.5 0.0 9.9 6.2 0.0 3.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PPR PF01535.20 KIK37773.1 - 0.12 12.7 2.9 18 5.9 0.1 4.0 5 0 0 5 5 4 0 PPR repeat TPR_16 PF13432.6 KIK37773.1 - 0.18 12.5 16.6 0.29 11.8 1.9 4.3 3 2 1 4 4 4 0 Tetratricopeptide repeat DUF3856 PF12968.7 KIK37773.1 - 0.5 10.4 1.9 74 3.4 0.0 4.0 4 1 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 KIK37773.1 - 1.3 9.5 12.2 11 6.7 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-CCHC_6 PF15288.6 KIK37774.1 - 0.39 10.6 1.9 1.1 9.1 2.0 1.7 1 1 0 1 1 1 0 Zinc knuckle Nop PF01798.18 KIK37777.1 - 0.14 11.6 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin DUF1687 PF07955.11 KIK37778.1 - 0.11 12.9 0.6 0.74 10.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1687) SIL1 PF16782.5 KIK37779.1 - 0.14 11.4 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 DEAD PF00270.29 KIK37780.1 - 1.7e-14 54.0 0.0 2.3e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK37780.1 - 1.5e-10 41.4 0.0 2.9e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK37780.1 - 0.006 16.6 0.0 0.0099 15.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2625 PF10946.8 KIK37782.1 - 0.057 12.5 0.1 0.076 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF2625 RVT_1 PF00078.27 KIK37784.1 - 2.3e-06 27.3 0.0 2.5e-06 27.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FlbD PF06289.11 KIK37785.1 - 0.071 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Flagellar and Swarming motility proteins HTH_Tnp_Tc5 PF03221.16 KIK37787.1 - 1e-07 31.9 0.1 1.2e-07 31.7 0.1 1.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain p450 PF00067.22 KIK37788.1 - 9.5e-63 212.5 0.0 1.1e-62 212.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK37791.1 - 7.6e-65 219.4 0.0 8.5e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L12 PF00542.19 KIK37794.1 - 1.3e-19 70.3 9.6 2.1e-19 69.6 4.0 2.3 2 1 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KIK37794.1 - 1.3e-13 50.4 7.2 6.9e-13 48.1 4.4 2.8 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 KIK37794.1 - 0.0035 17.9 4.9 0.0035 17.9 4.9 2.8 3 0 0 3 3 3 1 60s Acidic ribosomal protein DUF4587 PF15248.6 KIK37794.1 - 0.13 13.0 0.0 0.3 11.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4587) Not3 PF04065.15 KIK37795.1 - 1e-89 299.9 18.4 1.5e-89 299.4 18.4 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KIK37795.1 - 5.3e-45 152.7 7.9 2.1e-44 150.8 7.9 2.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 KIK37795.1 - 0.0018 18.6 2.9 0.0018 18.6 2.9 2.1 2 0 0 2 2 2 1 Syntaxin-like protein Cep57_MT_bd PF06657.13 KIK37795.1 - 0.053 14.0 4.4 0.066 13.7 0.8 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 SH3_1 PF00018.28 KIK37796.1 - 9e-23 79.6 0.0 4.4e-11 42.2 0.0 3.4 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 KIK37796.1 - 1.1e-18 66.8 0.1 1.1e-08 34.7 0.0 3.2 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 KIK37796.1 - 4.1e-14 52.0 0.0 9.1e-08 31.7 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 KIK37796.1 - 1.7e-06 28.0 0.1 3.3e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 PX domain AC_N PF16214.5 KIK37796.1 - 0.77 8.8 6.0 1.2 8.2 6.0 1.3 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Macoilin PF09726.9 KIK37796.1 - 5.8 5.3 4.9 7.7 4.9 4.9 1.1 1 0 0 1 1 1 0 Macoilin family NDUFA12 PF05071.16 KIK37797.1 - 8e-34 116.4 2.5 8e-34 116.4 2.5 1.4 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DAO PF01266.24 KIK37798.1 - 8.3e-51 173.6 0.0 1.1e-50 173.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Ribosomal_S7e PF01251.18 KIK37799.1 - 2.2e-85 285.0 2.6 2.2e-85 285.0 2.6 1.7 2 0 0 2 2 2 1 Ribosomal protein S7e TPR_1 PF00515.28 KIK37799.1 - 3.6e-15 55.0 7.5 1.1e-07 31.4 0.8 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK37799.1 - 8.9e-12 44.2 5.0 2.2e-06 27.4 0.7 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIK37799.1 - 7.9e-09 35.0 0.8 1.4e-05 24.9 0.6 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK37799.1 - 1.4e-05 25.3 1.6 0.014 15.7 0.4 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK37799.1 - 0.00017 21.4 0.5 0.2 11.7 0.4 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIK37799.1 - 0.00049 20.1 0.2 0.0013 18.7 0.2 1.7 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 KIK37799.1 - 0.0073 17.0 0.0 1 10.4 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIK37799.1 - 0.01 16.4 0.7 0.16 12.7 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK37799.1 - 0.018 15.5 0.4 0.6 10.7 0.1 3.1 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK37799.1 - 0.02 14.6 0.0 9.7 6.0 0.0 2.8 2 0 0 2 2 2 0 TPR repeat ANAPC3 PF12895.7 KIK37799.1 - 0.083 13.1 4.5 0.24 11.7 4.4 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KIK37799.1 - 0.36 11.3 2.5 19 5.9 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Ras PF00071.22 KIK37800.1 - 3.9e-46 156.6 0.0 1.3e-42 145.2 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KIK37800.1 - 4.2e-32 110.9 0.0 6.6e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK37800.1 - 4.5e-11 42.5 0.0 1.3e-10 41.0 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIK37800.1 - 1.2e-06 28.6 0.0 2.8e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KIK37800.1 - 0.0015 18.0 0.4 0.0066 15.9 0.0 2.2 2 1 1 3 3 3 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KIK37800.1 - 0.0024 17.3 0.0 0.0039 16.6 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KIK37800.1 - 0.0037 17.5 0.1 0.014 15.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 KIK37800.1 - 0.0085 15.8 0.1 0.29 10.9 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KIK37800.1 - 0.014 15.3 0.1 0.065 13.1 0.0 2.2 3 1 1 4 4 4 0 RsgA GTPase AAA_16 PF13191.6 KIK37800.1 - 0.04 14.3 0.0 0.075 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 KIK37800.1 - 0.04 14.0 0.0 0.089 12.8 0.0 1.6 2 0 0 2 2 2 0 Dynamin family AAA_7 PF12775.7 KIK37800.1 - 0.044 13.3 0.1 0.09 12.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KIK37800.1 - 0.16 11.6 0.0 0.36 10.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain AMMECR1 PF01871.17 KIK37801.1 - 3e-44 150.6 0.0 4.8e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 AMMECR1 PPR_2 PF13041.6 KIK37802.1 - 1.2e-12 47.8 0.2 0.00034 20.7 0.0 5.5 5 0 0 5 5 5 3 PPR repeat family PPR_3 PF13812.6 KIK37802.1 - 1.4e-12 47.4 0.1 0.0011 19.0 0.0 4.2 3 1 1 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 KIK37802.1 - 3.2e-12 45.8 0.7 0.00022 21.2 0.0 5.8 6 0 0 6 6 6 3 PPR repeat PPR_1 PF12854.7 KIK37802.1 - 9.8e-10 38.0 0.1 0.00015 21.4 0.0 4.3 4 0 0 4 4 4 2 PPR repeat ATP13 PF12921.7 KIK37802.1 - 0.19 11.6 0.0 3.2 7.6 0.0 2.7 2 1 1 3 3 3 0 Mitochondrial ATPase expression Med18 PF09637.10 KIK37803.1 - 0.055 13.3 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 Med18 protein Glyco_hydro_92 PF07971.12 KIK37803.1 - 0.072 12.0 0.1 0.072 12.0 0.1 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 FoP_duplication PF13865.6 KIK37804.1 - 0.19 12.3 5.8 0.44 11.1 5.8 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Na_H_Exchanger PF00999.21 KIK37805.1 - 5.5e-53 180.1 45.2 7.4e-53 179.7 45.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family LRR19-TM PF15176.6 KIK37808.1 - 0.02 14.9 0.1 0.031 14.3 0.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Comm PF15957.5 KIK37808.1 - 0.046 14.1 0.2 0.073 13.4 0.2 1.3 1 0 0 1 1 1 0 Commissureless IncD PF17628.2 KIK37809.1 - 0.083 12.7 0.0 0.091 12.5 0.0 1.1 1 0 0 1 1 1 0 Inclusion membrane protein D IIGP PF05049.13 KIK37810.1 - 3.1e-23 82.4 0.8 9.6e-23 80.8 0.0 2.1 2 1 0 2 2 2 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KIK37810.1 - 8.7e-06 25.8 0.3 2.8e-05 24.2 0.0 2.2 2 2 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK37810.1 - 0.011 15.7 0.7 0.026 14.4 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KIK37810.1 - 0.018 15.5 0.2 0.018 15.5 0.2 3.0 2 2 0 2 2 2 0 ABC transporter E2_bind PF08825.10 KIK37810.1 - 0.079 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 E2 binding domain Flavi_capsid PF01003.19 KIK37810.1 - 0.081 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Flavivirus capsid protein C PPP4R2 PF09184.11 KIK37810.1 - 4.3 6.8 10.3 7.3 6.1 10.3 1.4 1 0 0 1 1 1 0 PPP4R2 Peptidase_S64 PF08192.11 KIK37810.1 - 5.5 5.3 11.5 1.1 7.6 8.2 1.4 2 0 0 2 2 2 0 Peptidase family S64 Hamartin PF04388.12 KIK37810.1 - 8.1 5.0 12.5 13 4.3 12.5 1.2 1 0 0 1 1 1 0 Hamartin protein AAA_23 PF13476.6 KIK37810.1 - 8.4 6.8 16.3 29 5.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain MFS_1 PF07690.16 KIK37811.1 - 2.6e-17 62.8 55.5 3.5e-14 52.5 38.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PRP1_N PF06424.12 KIK37812.1 - 7e-50 169.3 2.8 1.6e-49 168.1 2.8 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KIK37812.1 - 4.6e-23 79.9 27.1 0.046 14.6 0.1 13.6 6 3 9 15 15 15 8 Tetratricopeptide repeat TPR_19 PF14559.6 KIK37812.1 - 4.2e-14 52.8 11.0 0.043 14.3 0.1 8.7 7 2 1 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIK37812.1 - 1e-13 51.6 8.6 0.00081 20.0 0.1 6.5 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK37812.1 - 0.00028 20.8 8.1 6.5 7.1 0.2 7.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_21 PF09976.9 KIK37812.1 - 0.0012 18.7 7.5 0.034 13.8 0.7 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 KIK37812.1 - 0.003 17.7 7.9 1.4 9.1 0.1 4.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK37812.1 - 0.007 16.6 0.8 3.1 8.1 0.4 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIK37812.1 - 0.068 13.8 8.3 43 5.0 0.0 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat NARP1 PF12569.8 KIK37812.1 - 0.22 10.4 5.7 8 5.2 0.0 3.9 4 1 1 5 5 5 0 NMDA receptor-regulated protein 1 ICMT PF04140.14 KIK37814.1 - 9.1e-13 48.4 0.3 2.3e-12 47.2 0.3 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK37814.1 - 7.8e-11 42.3 0.7 7.8e-11 42.3 0.7 2.0 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 KIK37814.1 - 2e-05 24.3 0.2 2.8e-05 23.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 KIK37814.1 - 0.0027 16.5 0.2 0.0045 15.8 0.2 1.4 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 KIK37814.1 - 0.0039 17.2 0.2 0.0084 16.1 0.2 1.6 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase HILPDA PF15220.6 KIK37814.1 - 0.15 12.2 0.6 0.33 11.1 0.6 1.5 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated DAHP_synth_2 PF01474.16 KIK37815.1 - 5.8e-197 654.5 0.0 6.5e-197 654.3 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family HECT PF00632.25 KIK37816.1 - 5.9e-95 318.3 0.0 8.1e-95 317.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) KKLCAg1 PF15204.6 KIK37816.1 - 0.11 12.6 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 Kita-kyushu lung cancer antigen 1 IQ PF00612.27 KIK37816.1 - 0.25 11.2 4.2 0.26 11.2 0.8 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif Polysacc_lyase PF14099.6 KIK37817.1 - 2.2e-05 24.4 0.2 0.00017 21.5 0.1 1.9 1 1 1 2 2 2 1 Polysaccharide lyase HET PF06985.11 KIK37818.1 - 2.1e-11 44.4 0.6 1.2e-07 32.1 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) zf-RVT PF13966.6 KIK37819.1 - 0.0031 18.2 0.1 0.0043 17.7 0.1 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase p450 PF00067.22 KIK37820.1 - 2.6e-67 227.6 0.0 3.3e-67 227.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NDK PF00334.19 KIK37821.1 - 0.00013 22.0 0.0 0.00028 20.9 0.0 1.6 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DER1 PF04511.15 KIK37822.1 - 1.6e-48 165.1 6.0 1.9e-48 164.9 6.0 1.0 1 0 0 1 1 1 1 Der1-like family SET PF00856.28 KIK37824.1 - 3.3e-11 43.9 0.0 6.6e-11 42.9 0.0 1.5 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KIK37824.1 - 2.8e-07 30.5 13.2 2.8e-07 30.5 13.2 1.8 2 0 0 2 2 2 1 MYND finger WD40 PF00400.32 KIK37825.1 - 1.8e-145 468.5 24.1 2.8e-09 37.4 0.0 14.7 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37825.1 - 3.1e-50 168.4 0.0 0.022 15.1 0.0 14.3 1 1 12 14 14 14 13 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK37825.1 - 3.1e-40 138.1 8.4 0.028 13.4 0.0 13.9 7 3 7 14 14 14 12 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK37825.1 - 2.6e-17 62.3 31.0 3.1 7.8 0.0 13.6 14 0 0 14 14 14 9 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK37825.1 - 2e-14 53.2 12.6 0.41 9.2 0.0 11.9 3 3 10 13 13 13 3 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK37825.1 - 2.1e-12 46.9 13.0 1.3 8.2 0.0 11.6 4 3 9 13 13 13 3 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK37825.1 - 1.8e-09 37.3 0.0 0.96 8.7 0.0 9.2 10 2 1 11 11 11 1 WD40-like domain Peptidase_S9_N PF02897.15 KIK37825.1 - 9.4e-08 31.3 0.0 6.6 5.4 0.0 7.0 2 2 2 6 6 6 1 Prolyl oligopeptidase, N-terminal beta-propeller domain AAA_16 PF13191.6 KIK37825.1 - 1.9e-06 28.4 0.0 6.1e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Frtz PF11768.8 KIK37825.1 - 0.00089 17.7 0.0 23 3.1 0.0 6.1 5 1 1 7 7 7 0 WD repeat-containing and planar cell polarity effector protein Fritz TolB_N PF04052.13 KIK37825.1 - 0.0049 17.0 0.1 1.8e+02 2.4 0.0 6.7 8 0 0 8 8 8 0 TolB amino-terminal domain AAA_22 PF13401.6 KIK37825.1 - 0.018 15.3 0.0 0.1 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KIK37825.1 - 0.021 14.0 0.1 0.035 13.2 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF5570 PF17731.1 KIK37825.1 - 0.042 13.9 30.3 18 5.5 0.1 10.1 1 1 10 12 12 12 0 Family of unknown function (DUF5570) APS_kinase PF01583.20 KIK37825.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.12 KIK37825.1 - 0.13 12.2 0.3 0.43 10.5 0.3 1.9 1 1 0 1 1 1 0 NACHT domain AAA_PrkA PF08298.11 KIK37825.1 - 0.24 10.3 0.0 0.41 9.5 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain ECH_1 PF00378.20 KIK37826.1 - 2e-63 214.0 0.1 2.8e-63 213.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIK37826.1 - 1e-34 120.6 0.0 1.4e-34 120.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Integrin_alpha PF00357.20 KIK37826.1 - 0.78 9.9 2.6 87 3.5 0.0 3.9 4 0 0 4 4 4 0 Integrin alpha cytoplasmic region ECH_1 PF00378.20 KIK37827.1 - 2.3e-72 243.3 0.4 2.5e-72 243.2 0.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIK37827.1 - 1.5e-40 139.7 0.3 3e-35 122.3 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SbcCD_C PF13558.6 KIK37828.1 - 1.3e-07 31.8 0.2 4.2e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 KIK37828.1 - 1.5e-07 31.1 0.0 1.6e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIK37828.1 - 4.3e-07 30.1 0.0 4.8e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIK37828.1 - 1.4e-05 25.0 0.1 1.7e-05 24.7 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain Barstar PF01337.18 KIK37828.1 - 0.072 13.1 0.0 0.4 10.7 0.0 2.0 2 0 0 2 2 2 0 Barstar (barnase inhibitor) Alg6_Alg8 PF03155.15 KIK37829.1 - 9.7e-136 453.5 14.8 1.3e-135 453.2 14.8 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family ALG3 PF05208.13 KIK37829.1 - 0.29 10.5 4.2 0.41 10.0 1.1 2.4 2 1 1 3 3 3 0 ALG3 protein CPDase PF07823.11 KIK37831.1 - 8.6e-08 32.1 0.0 9.6e-07 28.7 0.0 2.2 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 KIK37831.1 - 0.00067 19.6 0.0 0.00081 19.3 0.0 1.4 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily LNS2 PF08235.13 KIK37838.1 - 1.8e-97 325.3 0.0 2.4e-97 324.9 0.0 1.1 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KIK37838.1 - 7.1e-35 119.1 0.1 2.3e-34 117.4 0.0 2.0 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 KIK37838.1 - 0.056 13.0 0.0 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Lipin_mid PF16876.5 KIK37838.1 - 0.087 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain HAD PF12710.7 KIK37838.1 - 0.16 12.4 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Rhodanese PF00581.20 KIK37839.1 - 2.4e-07 31.2 0.0 6.7e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain Metallophos PF00149.28 KIK37842.1 - 4e-08 34.0 1.0 8.1e-08 33.0 1.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase IIGP PF05049.13 KIK37843.1 - 1.4e-25 90.2 1.6 1e-24 87.3 1.0 2.1 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KIK37843.1 - 1.8e-05 24.8 0.1 6.2e-05 23.1 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK37843.1 - 0.019 14.9 0.3 0.068 13.1 0.0 2.1 2 1 0 2 2 2 0 RsgA GTPase Ribosomal_S8 PF00410.19 KIK37843.1 - 0.052 13.5 0.2 0.052 13.5 0.2 1.7 2 0 0 2 2 2 0 Ribosomal protein S8 CBFD_NFYB_HMF PF00808.23 KIK37843.1 - 0.095 13.0 0.6 0.095 13.0 0.6 3.8 2 2 2 4 4 4 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Dynamin_N PF00350.23 KIK37843.1 - 0.18 11.8 4.2 0.35 10.9 0.0 2.6 2 2 0 2 2 2 0 Dynamin family CobU PF02283.16 KIK37843.1 - 0.2 11.2 0.1 0.2 11.2 0.1 2.9 3 1 0 3 3 3 0 Cobinamide kinase / cobinamide phosphate guanyltransferase ABC_tran PF00005.27 KIK37843.1 - 6.6 7.2 9.6 0.67 10.5 1.8 2.8 2 1 0 2 2 2 0 ABC transporter DUF1515 PF07439.11 KIK37847.1 - 0.052 13.6 0.1 0.08 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Med4 PF10018.9 KIK37847.1 - 0.068 12.8 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Fib_alpha PF08702.10 KIK37847.1 - 0.092 12.9 0.9 0.16 12.2 0.9 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family WD40 PF00400.32 KIK37849.1 - 2.8e-08 34.3 0.5 0.0021 18.8 0.1 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat eIF_4G1 PF12152.8 KIK37849.1 - 0.013 15.6 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4G1 Nucleoporin_N PF08801.11 KIK37849.1 - 0.078 11.7 0.3 1.4 7.6 0.0 2.4 2 1 0 3 3 3 0 Nup133 N terminal like E1-E2_ATPase PF00122.20 KIK37850.1 - 5.6e-05 22.7 1.3 5.7e-05 22.7 0.1 1.5 2 0 0 2 2 2 1 E1-E2 ATPase Aldo_ket_red PF00248.21 KIK37852.1 - 1.5e-47 162.3 0.0 7.9e-46 156.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family MIOX PF05153.15 KIK37854.1 - 2e-126 420.7 0.3 2.4e-126 420.4 0.3 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 KIK37854.1 - 0.0048 17.1 0.2 0.17 12.1 0.0 2.3 2 0 0 2 2 2 1 HD domain Cullin PF00888.22 KIK37854.1 - 0.012 14.2 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 0 Cullin family UBD PF16455.5 KIK37854.1 - 0.13 12.5 0.1 0.23 11.7 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-binding domain HAD PF12710.7 KIK37855.1 - 1.3e-20 74.6 0.0 1.9e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KIK37855.1 - 3.5e-08 33.2 0.1 3.9e-07 29.8 0.0 2.4 1 1 2 3 3 3 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 KIK37855.1 - 0.0068 16.7 0.2 0.7 10.1 0.0 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KIK37855.1 - 0.018 14.4 0.0 0.041 13.3 0.0 1.6 2 0 0 2 2 2 0 Putative Phosphatase Peptidase_S76 PF13611.6 KIK37855.1 - 0.02 15.2 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 Asp PF00026.23 KIK37858.1 - 1.8e-45 155.7 8.6 7.5e-45 153.7 8.6 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK37858.1 - 0.00049 20.4 2.2 0.00076 19.8 0.2 2.2 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KIK37858.1 - 0.0042 16.9 4.1 0.1 12.3 0.1 3.1 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal NTF2 PF02136.20 KIK37858.1 - 0.043 14.4 0.2 0.085 13.4 0.2 1.4 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Asp_protease_2 PF13650.6 KIK37858.1 - 0.057 14.1 1.1 17 6.2 0.1 2.9 2 1 0 2 2 2 0 Aspartyl protease CHAT PF12770.7 KIK37859.1 - 1.1e-37 130.0 0.0 2.3e-37 129.0 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 KIK37859.1 - 1.4e-10 41.3 7.8 0.041 14.2 0.1 6.7 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 KIK37859.1 - 1.5e-07 31.0 5.9 0.068 13.1 0.0 6.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK37859.1 - 2.6e-07 30.2 1.8 7 6.6 0.0 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK37859.1 - 3e-05 23.7 7.3 4.7 7.5 0.0 6.6 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK37859.1 - 0.0083 16.3 0.2 98 3.6 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat Surp PF01805.20 KIK37859.1 - 0.021 14.8 0.0 0.057 13.4 0.0 1.7 1 0 0 1 1 1 0 Surp module Sel1 PF08238.12 KIK37859.1 - 0.024 15.3 0.2 21 6.0 0.1 4.1 4 0 0 4 4 4 0 Sel1 repeat TPR_11 PF13414.6 KIK37859.1 - 0.03 14.0 0.2 18 5.1 0.0 4.9 6 0 0 6 6 6 0 TPR repeat TPR_2 PF07719.17 KIK37859.1 - 0.03 14.4 8.1 24 5.4 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK37859.1 - 0.088 13.5 5.5 5.6 7.7 0.1 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat Vta1_C PF18097.1 KIK37859.1 - 0.29 10.9 4.8 8.3 6.2 0.0 4.5 5 0 0 5 5 5 0 Vta1 C-terminal domain Amino_oxidase PF01593.24 KIK37862.1 - 0.00029 20.3 0.2 0.00052 19.4 0.2 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase zf-C2H2_11 PF16622.5 KIK37863.1 - 0.0011 18.7 2.4 0.002 17.9 0.4 2.3 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KIK37863.1 - 0.014 16.2 2.7 0.38 11.7 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Fer4_9 PF13187.6 KIK37863.1 - 0.28 11.4 2.2 0.77 10.0 2.2 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain zf-C2H2_2 PF12756.7 KIK37863.1 - 0.38 11.1 6.6 2.9 8.3 1.3 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-UBP PF02148.19 KIK37863.1 - 1.1 9.6 7.1 5.7 7.3 0.2 2.4 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C3HC4_5 PF17121.5 KIK37866.1 - 2.3e-13 49.8 4.1 3.2e-13 49.3 4.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) GAGA PF09237.11 KIK37866.1 - 0.017 14.9 2.2 0.027 14.3 2.2 1.5 1 1 0 1 1 1 0 GAGA factor Glyco_transf_41 PF13844.6 KIK37870.1 - 5e-100 335.2 0.4 2.2e-49 168.2 0.0 3.3 2 1 1 3 3 3 3 Glycosyl transferase family 41 TPR_17 PF13431.6 KIK37870.1 - 2.5e-08 33.7 0.2 0.014 15.7 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK37870.1 - 4.9e-08 32.5 0.0 6.3e-05 22.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK37870.1 - 4.6e-07 29.5 0.0 0.019 15.0 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK37870.1 - 8e-07 28.8 0.0 0.0089 16.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIK37870.1 - 0.00064 20.0 0.0 0.51 10.7 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK37870.1 - 0.00094 18.8 0.0 4.1 7.2 0.0 3.4 1 1 2 3 3 3 2 TPR repeat TPR_7 PF13176.6 KIK37870.1 - 0.0019 18.1 0.0 0.066 13.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIK37870.1 - 0.0029 17.4 0.0 0.023 14.6 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK37870.1 - 0.0034 18.1 0.0 3 8.9 0.0 3.6 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK37870.1 - 0.04 14.4 0.0 0.37 11.3 0.0 2.4 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK37870.1 - 0.1 13.2 0.0 0.66 10.7 0.0 2.4 2 1 0 2 2 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK37871.1 - 4.2e-32 107.6 2.1 6.5e-06 25.9 0.0 8.7 8 0 0 8 8 8 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK37871.1 - 4.2e-27 94.2 1.0 2.4e-10 40.5 0.0 6.1 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KIK37871.1 - 3.9e-26 89.7 3.8 1.1e-08 34.5 0.1 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK37871.1 - 2.9e-18 65.9 12.5 9.8e-09 35.4 0.3 7.7 6 1 3 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 KIK37871.1 - 7e-18 64.9 0.5 0.00045 20.7 0.0 6.8 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KIK37871.1 - 8.9e-18 63.0 0.5 1.3e-06 28.2 0.1 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIK37871.1 - 1.5e-15 57.6 1.7 4.6e-05 24.0 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK37871.1 - 6.4e-15 54.0 4.9 0.0037 17.2 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIK37871.1 - 4.5e-13 48.6 0.5 0.039 14.3 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 KIK37871.1 - 1.5e-09 37.9 13.6 0.0011 19.4 0.0 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK37871.1 - 1.7e-09 37.2 0.0 0.0012 18.5 0.0 5.1 5 1 1 6 6 5 2 TPR repeat TPR_14 PF13428.6 KIK37871.1 - 7.3e-09 35.7 5.0 3.2 8.8 0.0 7.8 5 3 3 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIK37871.1 - 1.4e-08 34.3 3.6 0.41 10.6 0.0 6.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 KIK37871.1 - 9.8e-08 32.0 1.3 0.0012 18.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIK37871.1 - 0.0014 18.6 3.8 0.013 15.5 0.2 3.8 4 1 1 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 KIK37871.1 - 0.0025 17.8 5.0 2.3 8.3 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK37871.1 - 0.0029 17.0 2.2 0.63 9.3 0.7 2.9 3 1 0 3 3 3 2 MalT-like TPR region TPR_15 PF13429.6 KIK37871.1 - 0.0035 16.6 0.5 3 7.0 0.1 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_18 PF13512.6 KIK37871.1 - 0.043 13.9 0.0 2.9 8.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat SNAP PF14938.6 KIK37871.1 - 0.05 13.0 0.1 0.88 8.9 0.0 2.6 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_4 PF07721.14 KIK37871.1 - 0.099 13.3 9.0 13 6.7 0.0 5.3 7 0 0 7 7 4 0 Tetratricopeptide repeat DUF2225 PF09986.9 KIK37871.1 - 0.17 11.6 0.1 0.51 10.0 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) ATP_sub_h PF10775.9 KIK37871.1 - 0.18 11.8 0.2 0.97 9.5 0.0 2.2 2 0 0 2 2 2 0 ATP synthase complex subunit h Pkinase PF00069.25 KIK37873.1 - 2.4e-64 217.3 0.0 3.8e-64 216.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK37873.1 - 2.7e-35 121.9 0.0 3.6e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK37873.1 - 2.4e-10 40.2 0.0 4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIK37873.1 - 0.0011 17.8 0.0 0.0019 17.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK37873.1 - 0.0012 18.8 1.6 0.0012 18.8 0.5 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK37873.1 - 0.052 12.5 0.5 0.098 11.6 0.5 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KIK37873.1 - 0.07 12.5 0.5 0.17 11.2 0.5 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIK37873.1 - 0.19 11.3 1.0 4.6 6.8 0.0 2.5 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Macro PF01661.21 KIK37874.1 - 1.8e-41 140.9 0.1 2.4e-41 140.5 0.1 1.2 1 0 0 1 1 1 1 Macro domain SAD_SRA PF02182.17 KIK37875.1 - 2e-48 164.0 0.1 2.5e-48 163.7 0.1 1.0 1 0 0 1 1 1 1 SAD/SRA domain Hydrolase_4 PF12146.8 KIK37877.1 - 2.8e-08 33.3 0.0 3.1e-06 26.7 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIK37877.1 - 1.1e-06 29.5 0.0 9.2e-05 23.1 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK37877.1 - 2.1e-06 27.6 0.0 4e-05 23.4 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK37877.1 - 0.00046 19.7 0.0 0.014 14.9 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KIK37877.1 - 0.00096 18.8 0.0 0.0021 17.7 0.0 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PE-PPE PF08237.11 KIK37877.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain FSH1 PF03959.13 KIK37877.1 - 0.057 13.1 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Complex1_LYR PF05347.15 KIK37878.1 - 8.5e-09 35.3 1.0 1.9e-08 34.2 1.0 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KIK37878.1 - 0.0034 18.1 1.6 0.004 17.9 1.6 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Sugar_tr PF00083.24 KIK37879.1 - 1.1e-53 182.7 21.6 1.4e-53 182.4 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK37879.1 - 8e-22 77.6 40.0 2.2e-21 76.2 24.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.22 KIK37880.1 - 9.7e-15 54.1 0.0 1.8e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KIK37880.1 - 0.0018 18.6 0.1 0.005 17.1 0.0 1.7 1 1 1 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter GMC_oxred_N PF00732.19 KIK37883.1 - 1.6e-65 221.4 0.0 2.1e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK37883.1 - 1.4e-06 27.6 0.1 2.6e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK37883.1 - 0.0003 20.0 0.4 0.076 12.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KIK37883.1 - 0.00099 18.4 0.1 0.0026 17.0 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KIK37883.1 - 0.027 13.7 0.0 0.052 12.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK37883.1 - 0.2 10.3 1.9 0.18 10.5 0.6 1.5 2 0 0 2 2 2 0 HI0933-like protein Peptidase_M20 PF01546.28 KIK37884.1 - 9.9e-27 94.0 0.0 3.9e-25 88.8 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIK37884.1 - 1.1e-09 38.1 0.0 2.6e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KIK37885.1 - 1.8e-31 109.4 0.0 2.8e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIK37885.1 - 1.1e-09 38.2 0.0 2.3e-09 37.1 0.0 1.5 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KIK37885.1 - 0.00017 21.4 0.0 0.00037 20.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Ribonucleas_3_3 PF14622.6 KIK37888.1 - 2.5e-08 34.1 0.0 4.9e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 KIK37888.1 - 3.4e-07 30.9 0.0 1.2e-06 29.2 0.0 1.9 2 0 0 2 2 2 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 KIK37888.1 - 0.00042 20.9 0.0 0.00085 19.9 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain FCH PF00611.23 KIK37889.1 - 3.1e-08 33.8 0.0 8e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.21 KIK37889.1 - 2.4e-06 27.5 0.0 4.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.27 KIK37889.1 - 7.5e-06 25.8 0.0 2.2e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain Histone_H2A_C PF16211.5 KIK37890.1 - 1.4e-17 63.1 0.9 3e-17 62.1 0.9 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KIK37890.1 - 2.9e-17 63.3 0.0 3.8e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KIK37890.1 - 1.5e-06 28.4 0.0 2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_M50B PF13398.6 KIK37891.1 - 3.6e-45 154.1 15.0 4.6e-45 153.7 15.0 1.1 1 0 0 1 1 1 1 Peptidase M50B-like DUF1317 PF07026.11 KIK37891.1 - 0.064 13.1 0.3 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1317) Fis1_TPR_C PF14853.6 KIK37892.1 - 1.4e-22 79.4 0.2 2.4e-22 78.8 0.2 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KIK37892.1 - 4e-17 61.6 0.0 6.6e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KIK37892.1 - 0.0036 17.3 0.1 0.0074 16.3 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK37892.1 - 0.036 14.6 0.0 0.058 13.9 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIK37892.1 - 0.067 13.9 0.0 0.2 12.4 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK37892.1 - 0.073 12.9 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat RRM_1 PF00076.22 KIK37893.1 - 1e-29 102.1 2.7 1.9e-15 56.4 0.1 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK37893.1 - 7.9e-06 25.9 0.0 0.00064 19.8 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 KIK37893.1 - 0.00061 19.6 0.0 0.27 11.1 0.0 3.0 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_9 PF18444.1 KIK37893.1 - 0.028 14.3 0.1 6.1 6.8 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif MTCP1 PF08991.10 KIK37894.1 - 1.4e-05 25.2 2.3 2e-05 24.7 2.3 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 KIK37894.1 - 5.8e-05 23.1 5.8 7.9e-05 22.7 5.8 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 KIK37894.1 - 0.0076 16.5 3.6 0.011 16.0 3.6 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.12 KIK37894.1 - 0.16 12.2 4.3 0.5 10.6 4.3 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Brix PF04427.18 KIK37895.1 - 1.9e-23 83.6 0.0 3.8e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Brix domain EMP24_GP25L PF01105.24 KIK37896.1 - 1e-49 169.0 0.5 1.2e-49 168.8 0.5 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD IL1 PF00340.19 KIK37896.1 - 0.009 15.7 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Interleukin-1 / 18 PAP_RNA-bind PF04926.15 KIK37896.1 - 0.029 14.0 0.1 0.053 13.2 0.1 1.4 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain SLC35F PF06027.12 KIK37897.1 - 1e-95 320.7 17.8 1.2e-95 320.5 17.8 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KIK37897.1 - 1.8e-09 37.0 0.6 3.5e-09 36.1 0.6 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like Deltameth_res PF16020.5 KIK37897.1 - 0.07 13.0 1.0 0.79 9.6 0.0 3.0 3 0 0 3 3 3 0 Deltamethrin resistance DUF3301 PF11743.8 KIK37898.1 - 0.1 12.3 0.2 0.24 11.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) Phage_GP20 PF06810.11 KIK37898.1 - 0.11 12.3 5.3 0.17 11.7 5.3 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 F-box-like PF12937.7 KIK37899.1 - 1.5e-08 34.4 5.8 6.5e-08 32.3 5.8 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK37899.1 - 0.042 13.7 8.4 0.088 12.7 3.9 3.3 2 1 0 2 2 2 0 F-box domain DUF1751 PF08551.10 KIK37900.1 - 0.044 14.4 3.7 0.08 13.5 2.9 2.0 1 1 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) DHHC PF01529.20 KIK37900.1 - 1.8 8.7 8.0 8.8 6.4 3.0 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase KTI12 PF08433.10 KIK37903.1 - 1.1e-77 261.2 0.0 1.2e-77 261.0 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KIK37903.1 - 1.9e-09 37.8 0.0 3.8e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK37903.1 - 0.15 12.3 0.0 0.79 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain PKcGMP_CC PF16808.5 KIK37904.1 - 0.019 14.8 0.6 0.037 13.9 0.6 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1192 PF06698.11 KIK37904.1 - 0.14 12.2 0.5 0.36 10.9 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF1151 PF06625.11 KIK37904.1 - 0.18 11.7 2.9 0.34 10.9 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) Vma12 PF11712.8 KIK37906.1 - 0.48 10.5 1.3 0.99 9.5 1.3 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Astro_capsid_p PF12226.8 KIK37908.1 - 1.1 8.4 10.5 1.9 7.6 10.5 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NOA36 PF06524.12 KIK37908.1 - 1.4 8.2 4.2 2.2 7.5 4.2 1.2 1 0 0 1 1 1 0 NOA36 protein UL42 PF17638.2 KIK37910.1 - 9.6 6.2 7.1 3.3 7.7 0.2 2.7 2 1 0 2 2 2 0 HCMV UL42 DUF805 PF05656.14 KIK37911.1 - 2.3 8.7 8.2 8.2 6.9 8.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF805) HTH_psq PF05225.16 KIK37912.1 - 0.14 11.9 0.0 2.8 7.7 0.0 2.2 2 0 0 2 2 2 0 helix-turn-helix, Psq domain WD40 PF00400.32 KIK37918.1 - 7e-34 115.3 4.9 3.4e-05 24.5 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37918.1 - 3e-10 40.2 0.4 0.054 13.8 0.0 5.8 2 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK37918.1 - 4.4e-05 22.6 0.1 1.6 7.6 0.0 4.1 2 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KIK37918.1 - 0.0075 15.9 1.1 0.025 14.2 1.1 1.8 1 1 0 2 2 2 1 PQQ-like domain PD40 PF07676.12 KIK37918.1 - 0.02 14.9 0.0 25 4.9 0.0 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK37918.1 - 0.069 11.8 0.0 0.16 10.6 0.0 1.6 2 1 0 2 2 2 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KIK37918.1 - 0.27 10.1 0.7 1.8 7.4 0.0 2.4 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain WD40 PF00400.32 KIK37919.1 - 2.2e-38 129.6 4.2 1.3e-05 25.8 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37919.1 - 1.8e-10 41.0 0.2 0.23 11.8 0.0 5.7 1 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK37919.1 - 1.6e-05 24.1 0.2 0.72 8.8 0.0 4.1 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK37919.1 - 0.0071 16.3 0.1 6.3 6.9 0.0 4.0 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 KIK37919.1 - 0.02 14.5 1.1 2.2 7.8 1.1 3.1 1 1 1 2 2 2 0 PQQ-like domain Cytochrom_D1 PF02239.16 KIK37919.1 - 0.028 12.9 0.0 5.1 5.5 0.0 2.8 2 1 1 3 3 3 0 Cytochrome D1 heme domain GSDH PF07995.11 KIK37919.1 - 0.031 13.6 0.0 0.41 9.9 0.0 2.1 2 0 0 2 2 2 0 Glucose / Sorbosone dehydrogenase Nup160 PF11715.8 KIK37919.1 - 0.031 12.9 0.0 0.086 11.5 0.0 1.9 1 1 0 1 1 1 0 Nucleoporin Nup120/160 PQQ PF01011.21 KIK37919.1 - 0.11 12.5 0.1 34 4.6 0.0 4.1 5 0 0 5 5 5 0 PQQ enzyme repeat WD40 PF00400.32 KIK37920.1 - 1.2e-27 95.6 1.4 2.2e-07 31.5 0.1 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37920.1 - 1.5e-10 41.2 0.0 0.21 11.9 0.0 4.3 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK37920.1 - 9.9e-07 28.0 0.4 0.18 10.7 0.1 3.4 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK37920.1 - 0.0089 15.9 0.1 3.5 7.7 0.0 3.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Calici_MSP PF05752.11 KIK37920.1 - 0.099 12.5 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Calicivirus minor structural protein PALB2_WD40 PF16756.5 KIK37920.1 - 0.11 11.4 0.2 1.4 7.8 0.0 2.1 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain WD40 PF00400.32 KIK37921.1 - 1.6e-39 133.2 4.6 1.5e-06 28.9 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37921.1 - 1.5e-09 38.0 0.1 1.4 9.3 0.0 6.0 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK37921.1 - 1.4e-07 30.8 0.1 0.011 14.7 0.0 3.8 2 2 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK37921.1 - 0.0028 16.4 0.1 0.036 12.7 0.0 2.2 2 1 0 2 2 2 1 Nucleoporin Nup120/160 PQQ PF01011.21 KIK37921.1 - 0.0052 16.7 0.1 0.95 9.5 0.0 3.4 3 0 0 3 3 3 1 PQQ enzyme repeat DUF1513 PF07433.11 KIK37921.1 - 0.0065 15.6 0.0 0.018 14.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1513) MMS1_N PF10433.9 KIK37921.1 - 0.033 12.8 0.0 0.82 8.2 0.0 2.1 1 1 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term PD40 PF07676.12 KIK37921.1 - 0.093 12.7 0.2 19 5.3 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Tyr_Deacylase PF02580.16 KIK37922.1 - 1.9e-54 184.1 0.1 2.5e-54 183.7 0.1 1.2 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Rep_fac-A_C PF08646.10 KIK37922.1 - 0.094 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain PLDc_2 PF13091.6 KIK37923.1 - 3.4e-11 43.1 0.0 0.00018 21.4 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KIK37923.1 - 8.1e-08 32.1 0.7 0.01 16.0 0.1 3.1 3 0 0 3 3 3 2 Phospholipase D Active site motif zf-C3HC4_3 PF13920.6 KIK37924.1 - 1.1e-08 34.8 15.9 1.1e-08 34.8 15.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK37924.1 - 0.0027 17.5 15.4 0.0052 16.6 15.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 YL1 PF05764.13 KIK37924.1 - 0.014 15.5 10.6 0.021 15.0 10.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein PTPRCAP PF15713.5 KIK37924.1 - 0.039 14.3 7.1 0.075 13.3 7.1 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated BUD22 PF09073.10 KIK37924.1 - 0.097 12.0 6.7 0.13 11.6 6.7 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KIK37924.1 - 0.18 10.0 7.8 0.25 9.5 7.8 1.1 1 0 0 1 1 1 0 Nop14-like family Tub_N PF16322.5 KIK37924.1 - 1 9.7 12.1 1.7 9.0 12.1 1.3 1 0 0 1 1 1 0 Tubby N-terminal Pes-10 PF07149.11 KIK37924.1 - 1.3 8.0 7.1 1.8 7.5 7.1 1.1 1 0 0 1 1 1 0 Pes-10 Cyclin_N PF00134.23 KIK37927.1 - 2.3e-10 40.3 0.0 3.2e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIK37927.1 - 9.9e-07 29.3 0.0 2.1e-06 28.2 0.0 1.6 2 0 0 2 2 2 1 Cyclin Ribosomal_S13_N PF08069.12 KIK37927.1 - 0.067 13.2 0.2 0.15 12.1 0.2 1.6 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain zf-C4H2 PF10146.9 KIK37928.1 - 8.5e-09 36.0 0.3 1.3e-08 35.4 0.3 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein DUF3450 PF11932.8 KIK37928.1 - 0.011 15.0 5.7 0.017 14.5 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Golgin_A5 PF09787.9 KIK37928.1 - 0.097 12.1 6.3 0.12 11.8 5.7 1.4 1 1 0 1 1 1 0 Golgin subfamily A member 5 APG6_N PF17675.1 KIK37928.1 - 0.11 13.0 8.3 0.19 12.2 8.3 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Spc7 PF08317.11 KIK37928.1 - 1.3 7.8 9.5 1.4 7.8 0.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DivIC PF04977.15 KIK37928.1 - 4.4 7.1 7.7 5.2 6.9 3.0 2.3 1 1 1 2 2 2 0 Septum formation initiator Acetyltransf_1 PF00583.25 KIK37929.1 - 1.4e-08 34.9 0.1 2e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KIK37929.1 - 1.1e-05 25.3 0.0 2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KIK37929.1 - 3.3e-05 24.2 0.1 4.8e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIK37929.1 - 0.00017 21.5 0.0 0.00026 21.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIK37929.1 - 0.034 14.2 0.1 0.08 13.0 0.1 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain IML1 PF12257.8 KIK37930.1 - 6.2e-106 353.7 0.0 8.9e-106 353.2 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KIK37930.1 - 5.1e-18 64.9 0.0 9.3e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Adeno_E3_CR2 PF02439.15 KIK37932.1 - 0.0089 15.8 0.3 0.019 14.7 0.3 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DHHC PF01529.20 KIK37933.1 - 4 7.5 4.9 12 6.0 2.8 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase Pkinase_fungal PF17667.1 KIK37934.1 - 1.4e-48 165.7 0.2 2.7e-32 112.1 0.1 2.0 1 1 1 2 2 2 2 Fungal protein kinase RIO1 PF01163.22 KIK37934.1 - 0.00019 21.1 0.0 0.00046 19.8 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 KIK37934.1 - 0.00051 19.5 0.0 0.0014 18.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK37934.1 - 0.0026 17.7 0.2 0.0047 16.9 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4803 PF16061.5 KIK37935.1 - 0.15 11.5 0.0 0.19 11.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4803) F-box-like PF12937.7 KIK37936.1 - 0.00041 20.2 0.1 0.0015 18.4 0.1 2.0 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KIK37939.1 - 9.7e-07 29.0 0.0 0.043 14.1 0.0 3.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK37939.1 - 3.3e-05 24.6 11.5 0.0021 18.9 0.1 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat PQQ_3 PF13570.6 KIK37939.1 - 0.09 13.3 0.4 1.7 9.2 0.1 3.1 3 0 0 3 3 3 0 PQQ-like domain AAA_lid_6 PF17866.1 KIK37940.1 - 5e-07 29.8 0.0 6.1e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 AAA lid domain HMG_box PF00505.19 KIK37942.1 - 9.6e-09 35.5 0.9 2e-08 34.5 0.9 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK37942.1 - 6.5e-07 29.8 0.6 6.5e-07 29.8 0.6 1.8 1 1 0 1 1 1 1 HMG-box domain YABBY PF04690.13 KIK37942.1 - 2.9e-06 27.9 5.6 4.3e-06 27.4 5.6 1.3 1 0 0 1 1 1 1 YABBY protein Ccdc124 PF06244.12 KIK37942.1 - 0.0042 17.6 3.6 0.0042 17.6 3.6 1.7 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 F-box PF00646.33 KIK37943.1 - 0.0036 17.1 0.5 0.01 15.7 0.5 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK37943.1 - 0.036 13.9 1.3 0.036 13.9 1.3 2.1 2 0 0 2 2 2 0 F-box-like DUF4419 PF14388.6 KIK37944.1 - 4.3e-89 298.9 0.0 1.2e-88 297.5 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) AAA_16 PF13191.6 KIK37948.1 - 0.00056 20.3 0.0 0.00064 20.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK37948.1 - 0.00059 19.8 0.0 0.00079 19.4 0.0 1.2 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 KIK37948.1 - 0.0041 17.5 0.0 0.0062 16.9 0.0 1.3 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 KIK37948.1 - 0.0096 15.1 0.1 0.013 14.7 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain Parvo_NS1 PF01057.17 KIK37948.1 - 0.019 14.1 0.0 0.055 12.6 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 APS_kinase PF01583.20 KIK37948.1 - 0.02 14.8 0.1 0.026 14.4 0.1 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 KIK37948.1 - 0.045 14.3 0.0 0.058 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 KIK37948.1 - 0.065 12.6 0.0 0.083 12.2 0.0 1.1 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain HemolysinCabind PF00353.19 KIK37949.1 - 3.8e-06 26.8 0.0 0.48 10.5 0.0 7.0 7 1 0 8 8 8 1 RTX calcium-binding nonapeptide repeat (4 copies) DUF2345 PF10106.9 KIK37949.1 - 0.028 14.3 0.0 0.11 12.4 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) Phage_int_SAM_1 PF02899.17 KIK37949.1 - 0.086 13.2 0.4 8.7 6.7 0.0 4.6 3 2 1 4 4 4 0 Phage integrase, N-terminal SAM-like domain Ppnp PF06865.11 KIK37949.1 - 0.6 10.6 2.8 22 5.6 0.0 4.6 5 1 0 5 5 5 0 Pyrimidine/purine nucleoside phosphorylase WD40 PF00400.32 KIK37950.1 - 1.2e-16 60.7 7.7 8.7e-08 32.7 2.1 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37950.1 - 1.5e-13 50.9 0.3 0.00019 21.6 0.1 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KIK37950.1 - 1.3e-05 24.7 0.5 0.0042 16.5 0.1 2.9 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK37950.1 - 1.5e-05 23.9 0.0 0.43 9.2 0.0 3.0 2 1 0 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK37950.1 - 6.6e-05 22.0 0.0 0.00029 19.9 0.0 1.9 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 KIK37950.1 - 0.00017 21.3 0.0 5.6 7.1 0.1 3.5 3 0 0 3 3 3 2 PQQ enzyme repeat PD40 PF07676.12 KIK37950.1 - 0.00041 20.2 3.5 1 9.4 0.0 3.7 3 1 0 3 3 3 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 KIK37950.1 - 0.001 18.7 2.3 0.038 13.6 0.3 2.0 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 KIK37950.1 - 0.0023 18.4 0.6 2.4 8.8 1.3 2.7 2 1 0 2 2 2 2 PQQ-like domain eIF2A PF08662.11 KIK37950.1 - 0.0095 15.8 0.2 0.032 14.1 0.2 1.8 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK37950.1 - 0.09 12.1 0.0 1.9 7.7 0.0 2.3 1 1 0 1 1 1 0 WD40-like domain AAA_12 PF13087.6 KIK37951.1 - 9e-58 195.2 0.0 1.8e-57 194.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK37951.1 - 1.6e-48 165.8 0.1 2.3e-48 165.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK37951.1 - 1.4e-14 54.7 0.2 3.8e-14 53.3 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIK37951.1 - 2e-11 43.9 0.1 3.5e-09 36.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KIK37951.1 - 3.9e-06 26.8 0.1 0.52 10.0 0.0 3.7 3 1 1 4 4 4 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KIK37951.1 - 1.4e-05 24.8 0.2 3.4e-05 23.5 0.2 1.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 KIK37951.1 - 0.0069 16.2 0.1 0.027 14.3 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain ResIII PF04851.15 KIK37951.1 - 0.025 14.6 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIK37951.1 - 0.03 14.6 0.1 0.34 11.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain Cob_adeno_trans PF01923.18 KIK37951.1 - 0.049 13.8 0.2 0.098 12.8 0.2 1.4 1 0 0 1 1 1 0 Cobalamin adenosyltransferase AAA PF00004.29 KIK37951.1 - 0.056 13.9 0.1 0.25 11.8 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK37951.1 - 0.066 13.6 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 KIK37951.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein Spc7 PF08317.11 KIK37951.1 - 0.16 10.8 1.1 0.25 10.2 1.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2075 PF09848.9 KIK37951.1 - 0.18 11.0 1.7 0.74 9.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) zf-RanBP PF00641.18 KIK37953.1 - 0.011 15.1 18.2 0.25 10.7 4.3 2.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others APC1_C PF18122.1 KIK37954.1 - 2.7e-34 118.5 0.4 6.9e-34 117.2 0.4 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain ANAPC1 PF12859.7 KIK37954.1 - 1e-05 26.1 0.0 3.4e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KIK37954.1 - 1.1 9.8 13.6 7.1 7.3 0.0 6.1 7 0 0 7 7 7 0 Proteasome/cyclosome repeat DAHP_synth_1 PF00793.20 KIK37956.1 - 1.3e-93 312.8 0.0 1.7e-93 312.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family PIH1 PF08190.12 KIK37957.1 - 1.4e-19 70.2 0.0 5.4e-18 65.0 0.0 2.2 2 0 0 2 2 2 2 PIH1 N-terminal domain PIH1_CS PF18201.1 KIK37957.1 - 0.18 12.2 0.0 1.8 9.1 0.0 2.2 2 0 0 2 2 2 0 PIH1 CS-like domain Arg_tRNA_synt_N PF03485.16 KIK37959.1 - 0.072 13.7 1.0 0.19 12.3 0.3 2.0 1 1 1 2 2 2 0 Arginyl tRNA synthetase N terminal domain HTH_19 PF12844.7 KIK37959.1 - 0.078 13.0 0.9 2.8 8.0 0.6 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain DUF4502 PF14950.6 KIK37960.1 - 0.063 12.7 0.1 0.091 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) Glyco_hydro_3 PF00933.21 KIK37962.1 - 2.1e-86 290.2 0.9 3.1e-86 289.6 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KIK37962.1 - 0.00085 19.3 0.1 0.026 14.5 0.0 2.6 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain VHS PF00790.19 KIK37964.1 - 2.5e-15 56.6 0.1 4.4e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 VHS domain HET PF06985.11 KIK37965.1 - 3.1e-11 43.8 2.0 4.1e-10 40.2 0.2 2.4 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) TPR_9 PF13371.6 KIK37965.1 - 0.17 12.0 0.8 4.2 7.6 0.6 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat RicinB_lectin_2 PF14200.6 KIK37967.1 - 4.4e-11 43.3 0.3 7.1e-08 33.1 0.3 2.3 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIK37967.1 - 0.00027 21.2 0.0 0.029 14.6 0.0 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Gti1_Pac2 PF09729.9 KIK37968.1 - 0.064 13.3 3.6 0.077 13.1 3.6 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4811 PF16069.5 KIK37968.1 - 0.49 10.3 4.9 0.61 10.0 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4811) DUF406 PF04175.12 KIK37968.1 - 0.89 10.1 6.6 1.4 9.5 6.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF406) Presenilin PF01080.17 KIK37968.1 - 1.7 7.4 4.5 1.7 7.3 4.5 1.0 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 KIK37968.1 - 4.5 7.0 9.6 5.1 6.8 9.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 YqfQ PF14181.6 KIK37968.1 - 5.2 7.2 8.5 6.6 6.9 8.5 1.2 1 0 0 1 1 1 0 YqfQ-like protein DDRGK PF09756.9 KIK37968.1 - 5.3 6.6 19.7 6.9 6.2 19.7 1.1 1 0 0 1 1 1 0 DDRGK domain Red1 PF07964.11 KIK37968.1 - 6.6 4.8 11.8 7.7 4.6 11.8 1.0 1 0 0 1 1 1 0 Rec10 / Red1 RNB PF00773.19 KIK37969.1 - 0.017 14.5 0.0 0.026 13.9 0.0 1.1 1 0 0 1 1 1 0 RNB domain WD40 PF00400.32 KIK37970.1 - 5.2e-08 33.4 1.0 6.4e-08 33.1 1.0 1.2 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK37970.1 - 0.07 13.4 0.0 0.07 13.4 0.0 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK37973.1 - 0.036 14.9 0.7 0.26 12.2 0.1 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF1125 PF06563.11 KIK37973.1 - 0.13 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1125) P63C PF10546.9 KIK37976.1 - 0.048 14.2 0.7 0.18 12.4 0.2 2.2 2 1 1 3 3 3 0 P63C domain DUF111 PF01969.17 KIK37977.1 - 0.16 11.1 0.1 0.19 10.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF111 Nop PF01798.18 KIK37982.1 - 2.6e-86 288.8 0.7 7.1e-86 287.4 0.0 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KIK37982.1 - 5.8e-22 77.8 0.1 5.8e-22 77.8 0.1 2.7 2 0 0 2 2 2 1 NOP5NT (NUC127) domain GCIP PF13324.6 KIK37982.1 - 8.7 5.9 12.7 8.6 5.9 10.7 2.0 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting AAA_23 PF13476.6 KIK37982.1 - 9.1 6.7 10.1 2 8.9 6.4 1.8 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 KIK37984.1 - 1.7e-06 28.0 0.0 2.4e-06 27.5 0.0 1.2 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK37984.1 - 2.3e-05 24.8 0.0 3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK37984.1 - 0.00088 19.6 0.0 0.0011 19.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KIK37984.1 - 0.034 14.6 0.0 0.05 14.0 0.0 1.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK37984.1 - 0.073 13.5 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Cytidylate_kin PF02224.18 KIK37984.1 - 0.091 12.5 0.0 0.092 12.5 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase HET PF06985.11 KIK37985.1 - 1.5e-09 38.4 4.2 1.4e-07 32.0 0.5 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_1 PF00515.28 KIK37985.1 - 0.0005 19.8 1.0 0.13 12.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK37985.1 - 0.0019 18.2 2.0 0.29 11.3 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK37985.1 - 0.0024 18.5 3.1 0.11 13.1 1.4 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK37985.1 - 0.004 17.1 1.6 3.3 7.9 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK37985.1 - 0.005 16.5 0.2 0.17 11.6 0.1 2.5 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.6 KIK37985.1 - 0.014 15.9 0.5 8.8 6.9 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK37985.1 - 0.017 15.9 3.8 6.2 7.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 KIK37985.1 - 0.082 13.0 0.3 21 5.3 0.1 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 KIK37985.1 - 0.2 11.7 1.2 6.1 6.9 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK37986.1 - 1.4e-07 31.0 0.0 1.4 8.8 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIK37986.1 - 7e-06 26.4 3.0 0.95 10.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK37986.1 - 7.1e-06 25.7 4.8 0.2 11.9 0.2 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK37986.1 - 7.9e-05 22.4 0.4 0.88 9.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK37986.1 - 0.0023 18.4 3.6 2 9.0 0.1 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat IPPT PF01715.17 KIK37986.1 - 0.0073 16.1 0.2 0.58 9.9 0.0 2.1 1 1 1 2 2 2 1 IPP transferase BTAD PF03704.17 KIK37986.1 - 0.017 15.6 2.1 20 5.6 0.0 3.0 1 1 2 3 3 3 0 Bacterial transcriptional activator domain PPR PF01535.20 KIK37986.1 - 0.065 13.5 0.0 5.7 7.4 0.0 2.7 2 0 0 2 2 2 0 PPR repeat TPR_16 PF13432.6 KIK37986.1 - 0.082 13.6 4.1 21 5.9 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF4574 PF15141.6 KIK37986.1 - 0.11 12.4 0.7 5.8 6.9 0.1 2.8 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 TPR_6 PF13174.6 KIK37986.1 - 0.59 10.9 4.0 3 8.7 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ABC_tran PF00005.27 KIK37987.1 - 5.8e-34 117.5 0.0 1e-33 116.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KIK37987.1 - 5.5e-24 85.3 5.8 1.9e-22 80.3 0.2 2.3 1 1 1 2 2 2 1 ABC transporter transmembrane region AAA_16 PF13191.6 KIK37987.1 - 0.0039 17.6 0.0 0.012 16.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KIK37987.1 - 0.0055 16.4 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIK37987.1 - 0.0094 15.9 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KIK37987.1 - 0.011 16.0 0.0 0.084 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KIK37987.1 - 0.044 13.6 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIK37987.1 - 0.049 13.1 0.0 0.69 9.3 0.0 2.0 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KIK37987.1 - 0.1 12.7 0.0 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 KIK37987.1 - 0.12 12.7 0.3 1.4 9.2 0.3 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 KIK37987.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KIK37987.1 - 0.19 12.2 0.0 0.32 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.22 KIK37990.1 - 1e-10 41.3 0.1 1.4e-10 40.8 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 KIK37991.1 - 1.5e-32 113.0 75.4 6.8e-31 107.5 72.6 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily zf-RING_UBOX PF13445.6 KIK37992.1 - 8.7e-05 22.5 7.0 8.7e-05 22.5 7.0 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIK37992.1 - 0.00064 19.5 12.3 0.013 15.3 4.4 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK37992.1 - 0.00094 19.5 7.1 0.00094 19.5 7.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK37992.1 - 0.0017 18.2 6.3 0.0017 18.2 6.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF3584 PF12128.8 KIK37992.1 - 0.0025 15.5 5.4 0.0032 15.1 5.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) zf-C3HC4 PF00097.25 KIK37992.1 - 0.0052 16.6 6.1 0.0052 16.6 6.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK37992.1 - 0.0085 16.2 5.3 0.0085 16.2 5.3 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING SWIRM-assoc_1 PF16495.5 KIK37992.1 - 0.0086 16.0 4.4 0.017 15.0 4.4 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 zf-RING_6 PF14835.6 KIK37992.1 - 0.013 15.3 1.9 0.024 14.5 1.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KIK37992.1 - 0.021 14.9 3.1 0.021 14.9 3.1 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 YscO-like PF16789.5 KIK37992.1 - 0.027 14.5 6.7 0.052 13.6 6.7 1.4 1 0 0 1 1 1 0 YscO-like protein Spc7 PF08317.11 KIK37992.1 - 0.039 12.8 6.1 0.051 12.4 6.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Uso1_p115_C PF04871.13 KIK37992.1 - 0.045 14.1 9.1 0.08 13.3 9.1 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HAUS5 PF14817.6 KIK37992.1 - 0.054 12.3 6.3 0.073 11.8 6.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Exonuc_VII_L PF02601.15 KIK37992.1 - 0.055 13.0 2.4 0.074 12.6 2.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CIAPIN1 PF05093.13 KIK37992.1 - 0.058 13.9 1.4 0.093 13.2 0.3 2.0 1 1 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis GP41 PF00517.17 KIK37992.1 - 0.11 12.4 0.5 0.17 11.8 0.5 1.2 1 0 0 1 1 1 0 Retroviral envelope protein zf-RING_5 PF14634.6 KIK37992.1 - 0.13 12.2 14.9 0.055 13.4 6.0 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-CpG_bind_C PF12269.8 KIK37992.1 - 0.22 11.3 6.1 0.13 12.0 4.0 1.6 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain Prok-RING_4 PF14447.6 KIK37992.1 - 0.32 10.9 13.1 1.9 8.4 6.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF349 PF03993.12 KIK37992.1 - 0.69 10.3 9.3 1.5 9.2 9.3 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) DUF3552 PF12072.8 KIK37992.1 - 0.84 9.0 10.9 1.3 8.4 10.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) SlyX PF04102.12 KIK37992.1 - 0.86 10.3 10.7 11 6.7 10.4 2.4 1 1 0 1 1 1 0 SlyX GrpE PF01025.19 KIK37992.1 - 1.3 8.7 7.0 0.71 9.5 4.8 1.6 1 1 1 2 2 2 0 GrpE Macoilin PF09726.9 KIK37992.1 - 1.5 7.2 6.6 1.9 6.9 6.6 1.1 1 0 0 1 1 1 0 Macoilin family OmpH PF03938.14 KIK37992.1 - 2 8.8 12.2 3.4 8.0 12.2 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Zn_ribbon_17 PF17120.5 KIK37992.1 - 9.6 5.9 11.3 16 5.2 0.5 2.6 2 1 1 3 3 3 0 Zinc-ribbon, C4HC2 type Med12 PF09497.10 KIK37993.1 - 1e-26 93.0 0.1 2.8e-26 91.6 0.1 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 NinE PF05322.11 KIK37994.1 - 0.054 13.4 0.0 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 NINE Protein CinA_KH PF18146.1 KIK37994.1 - 0.082 13.1 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain CTV_P13 PF06922.11 KIK37994.1 - 0.11 12.5 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Citrus tristeza virus P13 protein Plavaka PF18759.1 KIK37995.1 - 1e-120 402.9 0.0 1.5e-120 402.3 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIK37996.1 - 5.4e-60 203.3 0.1 9.8e-60 202.5 0.1 1.4 1 0 0 1 1 1 1 Plavaka transposase IBR PF01485.21 KIK37996.1 - 0.017 15.3 0.1 0.056 13.7 0.1 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain MRAP PF15183.6 KIK37996.1 - 0.05 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family WD40 PF00400.32 KIK38001.1 - 0.00059 20.6 0.1 0.0012 19.7 0.1 1.5 1 0 0 1 1 1 1 WD domain, G-beta repeat BRD4_CDT PF17105.5 KIK38002.1 - 0.078 12.6 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 Actin PF00022.19 KIK38009.1 - 1.4e-71 241.3 0.0 8.1e-71 238.8 0.0 1.8 1 1 0 1 1 1 1 Actin UbiA PF01040.18 KIK38011.1 - 7.3e-08 32.0 0.5 7.3e-08 32.0 0.5 2.3 2 1 0 2 2 2 1 UbiA prenyltransferase family DUF5575 PF17738.1 KIK38011.1 - 0.0021 17.1 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5575) DUF3043 PF11241.8 KIK38011.1 - 0.53 10.3 1.4 5 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) zf-RVT PF13966.6 KIK38014.1 - 0.0031 18.2 0.1 0.0043 17.7 0.1 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Anoctamin PF04547.12 KIK38018.1 - 3.8e-102 342.5 0.7 4.8e-102 342.1 0.7 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel RRM_1 PF00076.22 KIK38019.1 - 3.5e-31 106.8 0.2 2.1e-14 53.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK38019.1 - 1.4e-10 41.1 0.1 2.1e-05 24.5 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KIK38019.1 - 0.044 13.8 0.0 9.3 6.3 0.0 2.6 2 1 1 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KIK38019.1 - 0.13 12.3 0.0 22 5.2 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif Stm1_N PF09598.10 KIK38020.1 - 4.2 8.3 10.2 32 5.5 10.2 2.2 1 1 0 1 1 1 0 Stm1 SNO PF01174.19 KIK38021.1 - 1.8e-48 164.9 0.0 1.7e-46 158.5 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KIK38021.1 - 4.6e-09 36.1 0.0 6.2e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 KIK38021.1 - 0.0014 18.3 0.0 0.0021 17.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 KIK38021.1 - 0.0041 16.9 0.1 0.0063 16.3 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 KIK38021.1 - 0.026 14.3 0.1 0.11 12.2 0.1 1.9 1 1 0 1 1 1 0 Glutamine amidotransferase class-I Peptidase_S10 PF00450.22 KIK38022.1 - 2.1e-76 258.0 0.0 3e-76 257.5 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 KIK38023.1 - 9.2e-70 236.1 0.1 1.6e-69 235.4 0.1 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase DUF4337 PF14235.6 KIK38023.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DNA_binding_1 PF01035.20 KIK38024.1 - 6e-25 87.2 0.0 8.5e-25 86.7 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain HET PF06985.11 KIK38026.1 - 2.8e-09 37.5 4.2 9.5e-09 35.8 0.1 2.7 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) TPR_2 PF07719.17 KIK38027.1 - 0.0062 16.6 0.0 12 6.3 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK38027.1 - 0.016 15.0 0.6 17 5.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.32 KIK38028.1 - 1.4e-15 57.4 1.8 0.00036 21.3 0.3 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38028.1 - 0.00032 20.9 0.1 0.0066 16.7 0.0 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK38028.1 - 0.0046 16.0 0.1 0.56 9.1 0.0 2.6 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DNA_binding_1 PF01035.20 KIK38029.1 - 0.0055 16.8 0.0 0.008 16.3 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain RicinB_lectin_2 PF14200.6 KIK38033.1 - 2.7e-09 37.6 0.1 9.9e-07 29.4 0.0 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like LysM PF01476.20 KIK38034.1 - 3.9e-11 42.8 0.0 6e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 LysM domain MARVEL PF01284.23 KIK38035.1 - 4e-07 30.2 20.1 5.4e-07 29.7 20.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2650 PF10853.8 KIK38035.1 - 0.22 11.3 1.7 0.77 9.5 1.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) DPM3 PF08285.11 KIK38035.1 - 8.5 6.6 11.7 0.52 10.5 0.9 2.8 2 1 1 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) PfkB PF00294.24 KIK38036.1 - 7e-66 222.6 0.4 7.8e-66 222.4 0.4 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase zf-C2H2 PF00096.26 KIK38037.1 - 1.3e-09 38.0 5.9 0.00018 21.7 0.7 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK38037.1 - 2.4e-08 34.1 2.6 0.00021 21.9 0.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK38037.1 - 1.2e-06 28.7 1.6 0.019 15.3 0.5 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KIK38037.1 - 0.0001 22.2 1.0 0.0014 18.6 0.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 KIK38037.1 - 0.0006 20.1 0.3 0.5 10.8 0.0 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KIK38037.1 - 0.0067 16.8 7.8 0.036 14.5 0.2 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 KIK38037.1 - 0.029 14.0 0.1 0.092 12.4 0.0 1.9 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain CpXC PF14353.6 KIK38037.1 - 0.11 12.6 0.2 0.23 11.5 0.1 1.6 1 1 0 1 1 1 0 CpXC protein YdjO PF14169.6 KIK38037.1 - 0.21 11.4 2.6 0.15 11.8 0.5 1.8 2 0 0 2 2 2 0 Cold-inducible protein YdjO zf-H2C2_5 PF13909.6 KIK38037.1 - 0.32 10.8 3.0 0.94 9.3 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-RRN7 PF11781.8 KIK38037.1 - 0.43 10.3 2.0 16 5.3 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 CRAL_TRIO PF00650.20 KIK38038.1 - 5.8e-38 130.1 0.0 8.1e-38 129.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK38038.1 - 0.00015 21.8 0.2 0.00028 21.0 0.2 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KIK38038.1 - 0.032 14.4 0.0 0.066 13.4 0.0 1.5 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain AAA_9 PF12781.7 KIK38038.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 ATP-binding dynein motor region Nop10p PF04135.12 KIK38039.1 - 3.1e-21 75.1 0.3 3.6e-21 75.0 0.3 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Chitin_synth_2 PF03142.15 KIK38040.1 - 9.9e-278 922.0 0.0 1.3e-277 921.6 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KIK38040.1 - 6.1e-10 39.3 2.1 6.1e-10 39.3 2.1 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KIK38040.1 - 3e-08 33.8 0.0 1.6e-07 31.5 0.0 2.1 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KIK38040.1 - 0.00063 19.3 0.1 0.032 13.7 0.1 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KIK38040.1 - 0.14 12.0 0.0 1.7 8.4 0.0 2.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 GBR_NSP5 PF17580.2 KIK38042.1 - 0.11 12.3 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 PTE PF02126.18 KIK38043.1 - 0.011 15.2 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 0 Phosphotriesterase family Tautomerase_2 PF14552.6 KIK38043.1 - 0.16 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Tautomerase enzyme BTB_2 PF02214.22 KIK38043.1 - 0.18 12.1 0.0 2.2 8.7 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain DUF2288 PF10052.9 KIK38044.1 - 0.19 11.8 0.0 0.23 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2288) ICMT PF04140.14 KIK38045.1 - 9.3e-14 51.6 1.4 8.6e-13 48.5 0.2 2.6 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK38045.1 - 5.7e-12 46.0 4.0 7.3e-12 45.6 1.0 2.4 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIK38045.1 - 0.00024 20.0 0.1 0.00048 19.0 0.0 1.5 2 0 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family Thioredoxin PF00085.20 KIK38047.1 - 3.5e-15 55.8 0.0 3.7e-15 55.8 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KIK38047.1 - 1.5e-05 25.4 0.2 6.4e-05 23.4 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KIK38047.1 - 2.6e-05 24.1 0.0 2.6e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_4 PF13462.6 KIK38047.1 - 4.4e-05 23.7 0.3 8.5e-05 22.8 0.2 1.5 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 KIK38047.1 - 0.00018 21.8 0.0 0.00022 21.5 0.0 1.2 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KIK38047.1 - 0.0005 19.5 0.1 0.00056 19.4 0.1 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KIK38047.1 - 0.007 16.5 0.0 0.0081 16.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 KIK38047.1 - 0.013 15.7 0.0 0.021 15.0 0.0 1.3 1 1 0 1 1 1 0 Glutaredoxin Redoxin PF08534.10 KIK38047.1 - 0.088 12.5 0.0 0.088 12.5 0.0 1.1 1 0 0 1 1 1 0 Redoxin DUF4909 PF16253.5 KIK38047.1 - 0.12 12.2 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4909) ICMT PF04140.14 KIK38048.1 - 4.2e-15 55.9 0.3 4.2e-15 55.9 0.3 2.6 2 1 1 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK38048.1 - 8.9e-12 45.4 1.2 4.1e-11 43.2 0.6 2.2 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIK38048.1 - 2.5e-08 33.1 0.4 1.4e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family NADHdeh_related PF10125.9 KIK38048.1 - 0.0095 15.3 0.3 1.1 8.5 0.1 2.1 2 0 0 2 2 2 2 NADH dehydrogenase I, subunit N related protein ICMT PF04140.14 KIK38050.1 - 2.7e-15 56.5 4.4 2.7e-14 53.3 1.5 2.6 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK38050.1 - 1e-12 48.4 1.9 2.1e-11 44.2 0.7 2.3 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIK38050.1 - 2.5e-08 33.1 0.1 3.6e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 KIK38051.1 - 8.2e-16 58.2 0.9 8.2e-16 58.2 0.9 2.7 2 2 1 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK38051.1 - 9.3e-11 42.1 4.9 1e-10 42.0 2.1 2.3 2 1 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIK38051.1 - 1e-06 27.8 0.0 1e-06 27.8 0.0 1.4 2 0 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family ABC2_membrane_3 PF12698.7 KIK38054.1 - 1e-10 41.3 17.8 1.1e-10 41.2 13.7 2.0 1 1 1 2 2 2 2 ABC-2 family transporter protein XRN_N PF03159.18 KIK38056.1 - 5.5e-22 78.4 0.0 8.7e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 KIK38056.1 - 4.3e-14 52.3 0.0 7.2e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Xrn1 helical domain KCNQ_channel PF03520.14 KIK38056.1 - 0.12 12.2 0.9 0.98 9.2 0.2 2.2 2 0 0 2 2 2 0 KCNQ voltage-gated potassium channel RHD3 PF05879.12 KIK38059.1 - 0.00061 18.1 0.1 0.0008 17.7 0.1 1.2 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) HD_3 PF13023.6 KIK38062.1 - 0.14 12.1 0.2 0.18 11.7 0.2 1.1 1 0 0 1 1 1 0 HD domain RyR PF02026.16 KIK38066.1 - 0.01 16.0 0.1 0.01 16.0 0.1 2.0 2 1 1 3 3 3 0 RyR domain DUF3818 PF12825.7 KIK38066.1 - 0.14 11.1 1.2 0.2 10.6 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) SNF2_N PF00176.23 KIK38067.1 - 0.0017 17.1 0.0 0.0024 16.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK38068.1 - 3.8e-15 56.2 0.0 7.2e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KIK38068.1 - 4.3e-12 45.8 0.0 3.1e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase SNF2_N PF00176.23 KIK38068.1 - 7.7e-06 24.9 0.0 3.1e-05 22.9 0.0 1.9 2 1 0 2 2 2 1 SNF2 family N-terminal domain PKK PF12474.8 KIK38068.1 - 0.19 11.8 0.0 2.6 8.2 0.0 2.0 2 0 0 2 2 2 0 Polo kinase kinase VWA_2 PF13519.6 KIK38069.1 - 9.3e-08 32.7 0.0 1.3e-07 32.3 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KIK38069.1 - 4.3e-07 30.3 0.0 5.3e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain Integrin_beta PF00362.18 KIK38069.1 - 0.044 13.4 0.0 0.059 13.0 0.0 1.4 1 1 0 1 1 1 0 Integrin beta chain VWA domain G5 PF07501.12 KIK38076.1 - 0.1 13.1 1.4 0.13 12.7 0.1 1.8 2 1 0 2 2 2 0 G5 domain Pkinase_fungal PF17667.1 KIK38077.1 - 1.3e-16 60.4 1.2 1.5e-16 60.3 1.2 1.0 1 0 0 1 1 1 1 Fungal protein kinase Retrotrans_gag PF03732.17 KIK38080.1 - 2.1e-13 50.3 0.2 7.9e-13 48.5 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 KIK38080.1 - 3.4e-07 30.1 0.0 6.2e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Ntox34 PF15606.6 KIK38080.1 - 0.028 14.5 0.0 0.083 13.0 0.0 1.8 1 0 0 1 1 1 0 Bacterial toxin 34 zf-CCHC PF00098.23 KIK38080.1 - 2.3 8.5 6.1 1.8 8.8 3.8 2.0 2 1 0 2 2 2 0 Zinc knuckle RVP_2 PF08284.11 KIK38081.1 - 0.014 15.2 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KIK38081.1 - 0.021 15.4 0.0 0.022 15.4 0.0 1.1 1 0 0 1 1 1 0 Aspartyl protease Methyltransf_2 PF00891.18 KIK38090.1 - 1.1e-28 99.9 0.0 1.4e-26 93.1 0.0 2.2 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KIK38090.1 - 1.4e-05 25.7 0.0 4.7e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK38090.1 - 0.00011 22.1 0.0 0.00031 20.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK38090.1 - 0.00011 22.8 0.0 0.00032 21.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK38090.1 - 0.00012 21.6 0.0 0.00098 18.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KIK38090.1 - 0.0028 17.5 0.0 0.005 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK38090.1 - 0.019 15.6 0.0 0.089 13.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 KIK38090.1 - 0.037 13.7 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Met_10 PF02475.16 KIK38090.1 - 0.046 13.5 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein GidB PF02527.15 KIK38090.1 - 0.048 13.0 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G RPA_C PF08784.11 KIK38090.1 - 0.17 12.5 0.0 0.39 11.4 0.0 1.6 1 0 0 1 1 1 0 Replication protein A C terminal HhH-GPD PF00730.25 KIK38091.1 - 4e-20 72.3 0.0 7e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 KIK38091.1 - 5.9e-11 42.3 0.1 1.6e-08 34.5 0.2 3.3 2 1 0 2 2 2 1 NUDIX domain HHH PF00633.23 KIK38091.1 - 0.00024 20.8 0.0 0.00086 19.1 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif BRCT PF00533.26 KIK38092.1 - 0.0047 17.3 0.0 0.047 14.1 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain XPG_I_2 PF12813.7 KIK38093.1 - 6.1e-08 32.4 0.0 3.1e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 XPG domain containing XPG_N PF00752.17 KIK38093.1 - 0.00016 22.1 0.0 0.00049 20.5 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain NAD_kinase PF01513.21 KIK38095.1 - 9.4e-63 212.1 0.0 1.2e-62 211.7 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KIK38095.1 - 0.05 13.2 0.1 0.099 12.3 0.1 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain DUF287 PF03384.14 KIK38096.1 - 0.18 12.2 0.0 0.26 11.7 0.0 1.2 1 0 0 1 1 1 0 Drosophila protein of unknown function, DUF287 HTH_23 PF13384.6 KIK38097.1 - 0.024 14.4 0.1 0.06 13.2 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_32 PF13565.6 KIK38097.1 - 0.078 13.6 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain TerB_C PF15615.6 KIK38097.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 TerB-C domain Sigma70_r4 PF04545.16 KIK38097.1 - 0.14 11.7 0.0 0.45 10.1 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 TerB_C PF15615.6 KIK38099.1 - 0.043 14.1 1.1 0.39 11.0 0.0 2.4 1 1 1 2 2 2 0 TerB-C domain HTH_32 PF13565.6 KIK38099.1 - 0.089 13.4 0.8 0.17 12.5 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain UPF0158 PF03682.13 KIK38100.1 - 0.13 12.2 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) DUF3987 PF13148.6 KIK38102.1 - 0.039 13.0 0.1 0.73 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Isochorismatase PF00857.20 KIK38103.1 - 1.6e-28 100.1 0.1 2.4e-28 99.5 0.1 1.3 1 1 0 1 1 1 1 Isochorismatase family F-box-like PF12937.7 KIK38107.1 - 0.0021 17.9 1.9 0.0021 17.9 1.9 2.4 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIK38107.1 - 0.025 14.5 0.7 0.49 10.3 0.9 2.9 2 1 0 2 2 2 0 F-box domain Pkinase PF00069.25 KIK38108.1 - 4.9e-66 222.8 0.0 6.6e-65 219.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK38108.1 - 3.4e-36 124.8 0.0 3e-35 121.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KIK38108.1 - 1.8e-15 56.5 0.0 3e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 KIK38108.1 - 1.8e-06 27.5 0.1 3.5e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK38108.1 - 1.6e-05 25.0 0.7 0.0033 17.4 0.0 3.6 2 2 2 4 4 4 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK38108.1 - 2.7e-05 23.6 0.0 5.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIK38108.1 - 0.00012 21.2 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain WaaY PF06176.11 KIK38108.1 - 0.037 13.7 0.3 0.065 12.8 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) SPC12 PF06645.13 KIK38110.1 - 4.9e-25 87.4 0.7 5.4e-25 87.3 0.7 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MFS_1 PF07690.16 KIK38111.1 - 2.7e-42 145.0 47.0 4.3e-41 141.0 46.7 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily CBM_1 PF00734.18 KIK38112.1 - 0.023 14.6 1.6 0.025 14.5 0.1 1.9 2 0 0 2 2 2 0 Fungal cellulose binding domain AA_permease_2 PF13520.6 KIK38114.1 - 1.6e-58 198.5 44.8 5.6e-56 190.2 33.3 2.1 2 0 0 2 2 2 2 Amino acid permease DUF962 PF06127.11 KIK38114.1 - 0.088 12.9 0.4 0.9 9.7 0.4 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF962) RicinB_lectin_2 PF14200.6 KIK38115.1 - 4.9e-06 27.2 1.9 0.00074 20.2 0.1 2.9 2 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Hum_adeno_E3A PF05393.11 KIK38122.1 - 0.074 13.0 0.1 0.074 13.0 0.1 2.7 3 0 0 3 3 3 0 Human adenovirus early E3A glycoprotein Transposase_21 PF02992.14 KIK38123.1 - 2.8e-06 26.7 0.0 5.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 KIK38123.1 - 0.04 13.5 0.2 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) Spc29 PF17082.5 KIK38124.1 - 0.0022 17.9 1.3 0.0052 16.7 1.3 1.6 1 0 0 1 1 1 1 Spindle Pole Component 29 UPF0242 PF06785.11 KIK38124.1 - 0.21 11.7 1.4 0.53 10.4 1.4 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Med30 PF11315.8 KIK38124.1 - 0.39 10.9 3.5 3.6 7.8 0.3 2.5 2 0 0 2 2 2 0 Mediator complex subunit 30 DUF773 PF05600.12 KIK38124.1 - 1.1 7.9 8.1 3.2 6.4 2.0 2.1 2 0 0 2 2 2 0 CDK5 regulatory subunit-associated protein 3 ATG16 PF08614.11 KIK38124.1 - 3.5 7.8 10.6 0.083 13.1 3.3 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF16 PF01519.16 KIK38124.1 - 5.2 7.6 6.5 1.2 9.6 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 WD40 PF00400.32 KIK38125.1 - 1.1e-17 64.0 5.4 5.6e-05 23.8 0.4 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38125.1 - 0.0014 18.9 0.0 1.1 9.6 0.0 3.0 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK38125.1 - 0.0055 15.4 0.1 0.041 12.5 0.1 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 PD40 PF07676.12 KIK38125.1 - 0.016 15.2 0.1 7.6 6.6 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK38125.1 - 0.018 14.3 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal WD40 PF00400.32 KIK38129.1 - 9.8e-45 149.7 16.5 1.5e-07 32.0 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38129.1 - 2.5e-17 62.9 4.8 1.5e-05 25.2 0.0 6.3 1 1 6 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK38129.1 - 3.5e-08 32.6 3.5 0.7 8.5 0.1 5.1 3 1 1 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK38129.1 - 4.2e-06 26.8 0.1 7.9e-05 22.6 0.1 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK38129.1 - 2.4e-05 23.4 0.0 0.37 9.7 0.0 3.6 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 KIK38129.1 - 0.00026 20.8 0.6 0.035 13.8 1.0 2.4 2 1 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain WD40_like PF17005.5 KIK38129.1 - 0.0024 17.2 0.0 6.3 6.0 0.0 3.9 4 1 1 5 5 5 1 WD40-like domain Nbas_N PF15492.6 KIK38129.1 - 0.0043 16.4 0.1 0.06 12.7 0.0 2.7 2 1 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KIK38129.1 - 0.012 15.5 1.1 39 4.3 0.0 4.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 KIK38129.1 - 0.017 14.2 0.1 1.8 7.6 0.0 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1513) Hira PF07569.11 KIK38129.1 - 0.21 11.3 0.3 3.1 7.5 0.0 2.6 2 1 1 3 3 3 0 TUP1-like enhancer of split DUF4082 PF13313.6 KIK38129.1 - 0.29 11.2 3.5 0.61 10.1 1.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4082) WD40 PF00400.32 KIK38133.1 - 1.9e-74 243.7 26.5 8.7e-11 42.2 0.1 8.5 8 0 0 8 8 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38133.1 - 3.1e-26 91.5 0.0 0.0082 16.4 0.0 7.4 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK38133.1 - 6.2e-18 64.8 4.1 0.11 11.5 0.0 7.2 5 1 2 7 7 7 6 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK38133.1 - 6e-14 51.5 6.1 4.1 7.5 0.0 7.7 7 0 0 7 7 7 4 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK38133.1 - 4.9e-07 28.8 5.0 2.2 6.8 0.2 6.0 4 2 2 6 6 6 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KIK38133.1 - 5e-06 26.3 9.9 0.00026 20.6 1.6 2.5 1 1 1 2 2 2 2 PQQ-like domain eIF2A PF08662.11 KIK38133.1 - 1.4e-05 25.1 0.0 2.9 7.7 0.0 3.5 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KIK38133.1 - 4.4e-05 22.0 0.0 3.6 5.8 0.0 4.6 3 1 0 5 5 5 2 WD repeat-containing and planar cell polarity effector protein Fritz AAA_16 PF13191.6 KIK38133.1 - 0.00014 22.3 0.0 0.00034 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK38133.1 - 0.0018 18.2 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain WD40_3 PF15911.5 KIK38133.1 - 0.0021 18.0 0.4 70 3.5 0.0 5.8 6 0 0 6 6 6 0 WD domain, G-beta repeat WD40_like PF17005.5 KIK38133.1 - 0.005 16.2 0.0 19 4.4 0.0 4.4 3 1 1 5 5 5 0 WD40-like domain ATPase_2 PF01637.18 KIK38133.1 - 0.0056 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 KIK38133.1 - 0.012 14.7 0.0 0.027 13.6 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Cuticle_4 PF15955.5 KIK38133.1 - 0.029 15.1 4.6 22 5.8 0.0 5.9 8 0 0 8 8 6 0 Cuticle protein AAA_10 PF12846.7 KIK38133.1 - 0.073 12.0 0.0 0.25 10.2 0.0 1.8 2 1 0 2 2 2 0 AAA-like domain HCV_NS2 PF01538.18 KIK38133.1 - 0.091 12.4 0.0 13 5.3 0.1 3.7 4 0 0 4 4 4 0 Hepatitis C virus non-structural protein NS2 RNA_helicase PF00910.22 KIK38133.1 - 0.091 13.2 0.0 0.35 11.3 0.0 2.0 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 KIK38133.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 KIK38133.1 - 0.18 11.7 0.0 0.58 10.0 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase CAS_CSE1 PF03378.15 KIK38133.1 - 0.19 10.2 0.1 0.29 9.6 0.1 1.2 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus PQQ_3 PF13570.6 KIK38133.1 - 1.3 9.6 0.0 1.3 9.6 0.0 5.4 1 1 6 7 7 7 0 PQQ-like domain DUF5570 PF17731.1 KIK38133.1 - 2.2 8.4 16.1 39 4.3 0.1 5.9 2 2 4 6 6 6 0 Family of unknown function (DUF5570) TPR_2 PF07719.17 KIK38134.1 - 0.00032 20.6 0.6 2.8 8.3 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK38134.1 - 0.012 16.4 0.5 1.9 9.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PPTA PF01239.22 KIK38134.1 - 0.033 13.9 0.0 0.099 12.4 0.0 1.9 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat TPR_16 PF13432.6 KIK38134.1 - 0.17 12.6 1.3 4.6 8.0 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.32 KIK38135.1 - 1.7e-30 104.6 5.9 8.2e-08 32.8 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38135.1 - 7.2e-10 39.0 0.0 0.14 12.5 0.0 5.6 2 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK38135.1 - 0.00018 21.5 0.0 0.046 13.6 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK38135.1 - 0.0012 18.7 0.1 20 5.3 0.0 5.1 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Ret2_MD PF18528.1 KIK38135.1 - 0.038 14.4 0.0 5.6 7.4 0.0 3.4 4 1 0 4 4 4 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Ge1_WD40 PF16529.5 KIK38135.1 - 0.069 12.1 5.6 1.4 7.8 0.1 3.9 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Glyco_hydro_31 PF01055.26 KIK38136.1 - 3e-137 458.4 2.3 4.1e-137 458.0 2.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KIK38136.1 - 2.2e-18 66.3 0.2 2.3e-17 63.1 0.1 2.9 3 0 0 3 3 3 1 Galactose mutarotase-like DUF5110 PF17137.4 KIK38136.1 - 0.00011 22.4 0.1 0.00023 21.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Lectin_C PF00059.21 KIK38136.1 - 0.94 10.2 2.5 65 4.3 1.2 3.0 3 0 0 3 3 3 0 Lectin C-type domain NHase_beta PF02211.15 KIK38137.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Nitrile hydratase beta subunit zf-HC5HC2H_2 PF13832.6 KIK38140.1 - 0.023 14.9 2.4 0.025 14.7 2.4 1.3 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-H2C2_2 PF13465.6 KIK38142.1 - 0.0055 17.1 2.2 0.013 15.9 2.2 1.7 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KIK38142.1 - 0.084 13.2 0.4 0.084 13.2 0.4 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KIK38142.1 - 0.44 10.5 2.3 22 5.1 1.0 2.7 2 1 0 2 2 2 0 zinc-finger of a C2HC-type Ribosomal_L24e PF01246.20 KIK38146.1 - 0.032 14.4 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L24e MMR_HSR1 PF01926.23 KIK38147.1 - 0.0001 22.3 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KIK38147.1 - 0.00021 20.8 0.0 0.00027 20.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KIK38147.1 - 0.0015 18.8 0.0 0.0022 18.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KIK38147.1 - 0.0044 16.5 0.0 0.006 16.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein ATP-synt_ab PF00006.25 KIK38147.1 - 0.036 13.7 0.0 0.043 13.5 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain FeoB_N PF02421.18 KIK38147.1 - 0.081 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 KIK38147.1 - 0.087 12.3 0.1 0.19 11.2 0.1 1.5 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 KIK38147.1 - 0.095 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 KIK38147.1 - 0.11 11.8 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Septin ATPase_2 PF01637.18 KIK38147.1 - 0.13 12.2 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KIK38147.1 - 0.13 11.4 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain WD40 PF00400.32 KIK38149.1 - 2.3e-30 104.2 17.3 4.2e-08 33.7 0.1 6.7 5 1 1 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38149.1 - 3.8e-12 46.3 0.1 0.026 14.8 0.0 4.6 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WW PF00397.26 KIK38149.1 - 1.4e-07 31.5 4.0 3.7e-06 26.9 0.8 3.2 2 0 0 2 2 2 1 WW domain Nup160 PF11715.8 KIK38149.1 - 9.7e-06 24.5 0.0 0.045 12.4 0.0 3.4 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK38149.1 - 1.8e-05 23.9 0.0 0.41 9.6 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PUA_3 PF17785.1 KIK38149.1 - 0.13 12.1 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 PUA-like domain zf-H2C2_2 PF13465.6 KIK38150.1 - 0.03 14.7 2.7 0.03 14.7 2.7 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Oxidored_FMN PF00724.20 KIK38151.1 - 1.4e-57 195.6 0.0 1.8e-57 195.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ICMT PF04140.14 KIK38152.1 - 1e-16 61.1 0.4 3.5e-15 56.2 0.0 2.4 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK38152.1 - 5.6e-09 36.3 0.5 5.6e-09 36.3 0.5 2.5 2 1 1 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIK38152.1 - 2.1e-06 26.8 0.1 3.2e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 KIK38153.1 - 1.1e-15 57.8 1.4 1.1e-14 54.6 0.1 2.2 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK38153.1 - 1.4e-07 31.9 2.8 1.4e-07 31.9 2.8 2.4 2 1 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIK38153.1 - 2.6e-06 26.5 0.1 3.6e-06 26.0 0.1 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KIK38153.1 - 0.00054 19.6 0.4 0.0012 18.4 0.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ABA_GPCR PF12430.8 KIK38155.1 - 5.6e-34 117.5 3.7 1.2e-33 116.4 3.7 1.5 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KIK38155.1 - 1.1e-10 41.5 0.2 1.1e-10 41.5 0.2 1.9 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal DHHC PF01529.20 KIK38156.1 - 4.5e-31 107.7 8.5 4.5e-31 107.7 8.5 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase TLC PF03219.14 KIK38156.1 - 0.038 12.7 0.2 0.062 12.0 0.2 1.3 1 0 0 1 1 1 0 TLC ATP/ADP transporter Ribosomal_L40e PF01020.17 KIK38156.1 - 0.067 13.1 1.7 0.14 12.1 1.7 1.4 1 0 0 1 1 1 0 Ribosomal L40e family ADH_zinc_N PF00107.26 KIK38158.1 - 2.4e-28 98.7 0.3 3.5e-28 98.2 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK38158.1 - 2.4e-19 70.7 0.1 5.9e-19 69.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK38158.1 - 3.2e-10 39.8 0.2 1.8e-09 37.5 0.2 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain RNA_pol_I_A49 PF06870.12 KIK38159.1 - 1.1e-106 357.0 0.1 1.4e-106 356.7 0.1 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor SRI PF08236.11 KIK38160.1 - 2.5e-20 72.4 11.3 1.1e-19 70.3 11.3 2.2 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 KIK38160.1 - 1.6e-17 64.4 7.1 8.3e-17 62.1 0.2 3.4 2 2 0 2 2 2 1 SET domain AWS PF17907.1 KIK38160.1 - 1.7e-13 50.4 9.1 1.7e-13 50.4 9.1 1.9 2 0 0 2 2 2 1 AWS domain ACC_epsilon PF13822.6 KIK38160.1 - 0.57 10.9 5.7 1.8 9.3 5.7 1.8 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Complex1_LYR PF05347.15 KIK38163.1 - 5e-13 48.9 0.1 7.3e-13 48.4 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KIK38163.1 - 0.00013 22.6 0.2 0.00025 21.7 0.2 1.6 1 1 0 1 1 1 1 Complex1_LYR-like PP28 PF10252.9 KIK38164.1 - 3.9e-24 84.9 15.4 3.9e-24 84.9 15.4 3.1 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 Arm PF00514.23 KIK38165.1 - 3.3e-05 23.8 1.9 13 6.0 0.0 6.7 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Mo25 PF08569.11 KIK38165.1 - 0.00055 19.4 0.7 0.024 14.0 0.0 2.3 2 1 0 2 2 2 1 Mo25-like KAP PF05804.12 KIK38165.1 - 0.01 14.0 1.4 0.8 7.8 0.0 3.1 3 1 0 3 3 3 0 Kinesin-associated protein (KAP) Proteasom_PSMB PF10508.9 KIK38165.1 - 0.012 14.2 1.9 1.4 7.3 0.1 3.0 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit Tho2 PF11262.8 KIK38165.1 - 0.015 14.5 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 MOR2-PAG1_C PF14225.6 KIK38165.1 - 0.031 14.1 0.7 1.6 8.5 0.1 2.9 2 1 0 3 3 3 0 Cell morphogenesis C-terminal DUF2235 PF09994.9 KIK38166.1 - 8.7e-82 274.7 0.1 1.8e-81 273.7 0.1 1.5 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF3328 PF11807.8 KIK38168.1 - 1.4e-60 204.8 0.3 1.7e-60 204.5 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KIK38170.1 - 5.8e-57 193.0 0.3 6.8e-57 192.8 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Vwaint PF14624.6 KIK38170.1 - 0.081 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 VWA / Hh protein intein-like Hepatitis_core PF00906.20 KIK38170.1 - 0.13 11.8 1.8 1.8 8.0 0.1 2.4 2 1 1 3 3 3 0 Hepatitis core antigen DUF4727 PF15856.5 KIK38170.1 - 0.49 9.9 3.7 0.17 11.5 0.2 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4727) PDEase_I PF00233.19 KIK38173.1 - 0.061 13.0 1.6 0.16 11.6 1.6 1.7 1 1 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Ribosomal_S4e PF00900.20 KIK38174.1 - 8.9e-37 124.9 0.0 2.6e-36 123.4 0.0 1.8 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KIK38174.1 - 7.2e-26 89.6 0.1 1.2e-25 88.8 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KIK38174.1 - 3.7e-21 74.9 5.8 7.9e-21 73.9 5.8 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KIK38174.1 - 7.5e-06 25.6 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KIK38174.1 - 4.2e-05 23.3 3.0 0.00013 21.8 3.0 1.9 1 0 0 1 1 1 1 KOW motif Sipho_tail PF05709.11 KIK38174.1 - 0.075 12.4 0.1 0.099 12.0 0.1 1.3 1 0 0 1 1 1 0 Phage tail protein Glucosamine_iso PF01182.20 KIK38175.1 - 1.9e-20 73.7 0.0 2.9e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF92 PF01940.16 KIK38176.1 - 7.7e-73 244.8 6.0 9e-73 244.6 6.0 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 Glycogen_syn PF05693.13 KIK38178.1 - 0 1090.1 0.0 0 1089.9 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.11 KIK38178.1 - 3.8e-07 30.1 1.4 4.6e-07 29.8 0.2 1.7 2 0 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KIK38178.1 - 1.2e-06 28.2 0.0 0.00045 19.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIK38178.1 - 2.5e-06 28.0 0.0 0.004 17.6 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIK38178.1 - 3.2e-06 27.7 0.4 9.5e-06 26.1 0.4 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KIK38178.1 - 3.3e-05 23.9 1.1 6.7e-05 23.0 1.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Aldedh PF00171.22 KIK38179.1 - 3.4e-115 385.2 0.0 1.2e-114 383.4 0.0 1.7 1 1 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIK38179.1 - 4.5e-05 22.7 0.0 7.9e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Ribosomal_S17 PF00366.20 KIK38179.1 - 0.098 12.8 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S17 PCI PF01399.27 KIK38180.1 - 1.9e-05 25.1 0.9 3.2e-05 24.4 0.9 1.4 1 0 0 1 1 1 1 PCI domain HSP20 PF00011.21 KIK38181.1 - 3.4e-23 81.7 0.2 4.4e-23 81.4 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIK38181.1 - 3e-11 42.7 0.0 4.3e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 KIK38181.1 - 0.0092 17.0 0.1 0.042 14.9 0.0 2.0 2 0 0 2 2 2 1 CS domain DUF4097 PF13349.6 KIK38181.1 - 0.19 11.0 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Putative adhesin DUF4524 PF15025.6 KIK38182.1 - 0.015 15.1 0.1 0.023 14.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) MRG PF05712.13 KIK38183.1 - 2.3e-54 183.7 0.0 3.1e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KIK38183.1 - 2.4e-10 40.1 0.1 4e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KIK38183.1 - 0.068 13.1 0.4 0.14 12.1 0.4 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Pkinase PF00069.25 KIK38184.1 - 2e-22 79.8 0.0 2.5e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK38184.1 - 3.3e-10 39.7 0.0 3.7e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK38184.1 - 1.1e-08 34.3 0.3 1.4e-08 33.9 0.3 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK38184.1 - 0.0062 16.5 0.2 0.026 14.4 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family EnY2 PF10163.9 KIK38185.1 - 8.7e-21 74.1 0.2 1e-20 73.9 0.2 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF4451 PF14616.6 KIK38186.1 - 6.4e-13 49.0 0.4 7.7e-13 48.7 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) EMP24_GP25L PF01105.24 KIK38188.1 - 1.5e-42 145.6 0.0 1.7e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Herpes_UL49_5 PF05702.11 KIK38188.1 - 0.079 13.1 0.5 0.24 11.5 0.0 2.0 3 0 0 3 3 3 0 Herpesvirus UL49.5 envelope/tegument protein Redoxin PF08534.10 KIK38189.1 - 5.5e-26 91.0 0.0 6.6e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KIK38189.1 - 5e-12 45.8 0.0 6e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family SNF2_assoc PF08455.10 KIK38189.1 - 0.24 10.4 0.0 0.27 10.2 0.0 1.0 1 0 0 1 1 1 0 Bacterial SNF2 helicase associated Fer2_3 PF13085.6 KIK38192.1 - 2e-32 111.4 0.0 3.1e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KIK38192.1 - 1.9e-10 41.1 8.1 1.9e-10 41.1 8.1 2.3 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KIK38192.1 - 1.7e-07 31.3 4.4 1.7e-07 31.3 4.4 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KIK38192.1 - 2e-06 28.2 9.6 2e-06 28.2 9.6 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KIK38192.1 - 0.00024 21.6 5.2 0.00024 21.6 5.2 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 KIK38192.1 - 0.0036 17.2 4.2 0.0037 17.2 0.5 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 KIK38192.1 - 0.096 12.9 4.6 0.43 10.8 0.1 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain PIN_4 PF13638.6 KIK38193.1 - 1.5e-06 28.5 0.1 2.9e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 PIN domain PID PF00640.23 KIK38193.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) ZapB PF06005.12 KIK38194.1 - 0.16 12.4 3.8 0.39 11.2 3.8 1.6 1 0 0 1 1 1 0 Cell division protein ZapB NRBF2 PF08961.10 KIK38194.1 - 0.23 11.0 2.0 0.45 10.1 2.0 1.4 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator UQ_con PF00179.26 KIK38196.1 - 3.7e-48 162.7 0.0 4.2e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIK38196.1 - 0.0013 18.4 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KIK38196.1 - 0.016 15.0 0.1 0.034 14.0 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 KIK38196.1 - 0.052 13.8 0.2 0.081 13.2 0.2 1.4 1 1 0 1 1 1 0 RWD domain Skp1_POZ PF03931.15 KIK38197.1 - 6e-08 32.7 0.1 1.2e-07 31.7 0.1 1.5 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain Metallophos PF00149.28 KIK38198.1 - 5.3e-29 102.2 0.1 8.5e-29 101.5 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RVP_2 PF08284.11 KIK38203.1 - 7.8e-11 41.9 0.0 1.2e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KIK38203.1 - 6.5e-07 29.9 0.0 1.1e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK38203.1 - 2.7e-06 27.8 0.0 4.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KIK38203.1 - 3.2e-05 23.7 0.0 4.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.8 KIK38203.1 - 0.0022 17.6 0.1 0.0037 16.8 0.1 1.3 1 0 0 1 1 1 1 Ty3 transposon peptidase Retrotrans_gag PF03732.17 KIK38204.1 - 0.00088 19.5 2.8 0.002 18.3 2.0 2.0 1 1 1 2 2 2 1 Retrotransposon gag protein Rx_N PF18052.1 KIK38204.1 - 0.058 13.7 1.1 0.47 10.8 0.1 2.3 2 0 0 2 2 2 0 Rx N-terminal domain PNMA PF14893.6 KIK38204.1 - 0.065 12.6 0.1 0.086 12.2 0.1 1.2 1 0 0 1 1 1 0 PNMA NAT PF04768.13 KIK38205.1 - 2.6e-46 157.4 0.0 3.9e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 KIK38205.1 - 2.5e-26 92.5 0.0 5.6e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 KIK38205.1 - 2.5e-24 86.2 0.0 5e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family MarR_2 PF12802.7 KIK38205.1 - 0.16 11.8 1.6 7.5 6.5 0.2 3.3 3 0 0 3 3 3 0 MarR family Glyco_hydro_31 PF01055.26 KIK38206.1 - 1.7e-139 465.8 2.8 2.1e-139 465.5 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KIK38206.1 - 1.9e-28 99.0 0.0 3.9e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KIK38206.1 - 0.00012 22.3 0.1 0.0045 17.3 0.0 2.9 2 0 0 2 2 2 1 Galactose mutarotase-like Glyco_hydro_31 PF01055.26 KIK38207.1 - 6.6e-137 457.3 2.0 8.3e-137 457.0 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KIK38207.1 - 2.9e-28 98.4 0.0 5.4e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KIK38207.1 - 1.8e-05 25.0 0.1 0.0024 18.1 0.0 3.2 3 0 0 3 3 3 1 Galactose mutarotase-like Phage_integrase PF00589.22 KIK38208.1 - 0.003 17.4 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family C1_2 PF03107.16 KIK38209.1 - 0.046 14.0 3.6 1.1 9.6 0.5 2.4 2 0 0 2 2 2 0 C1 domain zf-HIT PF04438.16 KIK38209.1 - 0.26 11.2 5.7 0.81 9.6 1.3 2.4 2 0 0 2 2 2 0 HIT zinc finger Ribosomal_L37e PF01907.19 KIK38209.1 - 1.6 9.0 9.7 4.3 7.6 2.9 2.4 2 0 0 2 2 2 0 Ribosomal protein L37e zf-CCHC PF00098.23 KIK38209.1 - 6.2 7.1 9.0 0.29 11.3 2.5 2.0 2 0 0 2 2 2 0 Zinc knuckle WD40 PF00400.32 KIK38210.1 - 9.3e-22 76.9 14.2 2.7e-08 34.3 0.5 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 KIK38210.1 - 0.0003 19.6 0.2 0.5 8.9 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PD40 PF07676.12 KIK38210.1 - 0.0041 17.0 0.1 6.7 6.8 0.0 3.3 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat zf-C2H2 PF00096.26 KIK38212.1 - 0.00073 19.9 1.8 0.00073 19.9 1.8 1.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK38212.1 - 0.0023 18.6 0.8 0.0023 18.6 0.8 1.7 2 0 0 2 2 2 1 C2H2-type zinc finger GAGA PF09237.11 KIK38212.1 - 0.0031 17.3 2.0 0.0037 17.0 1.8 1.4 1 1 0 1 1 1 1 GAGA factor zf-C2H2_9 PF16293.5 KIK38212.1 - 0.0045 16.8 0.3 0.0065 16.3 0.3 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (1 copy) zf-C2HE PF16278.5 KIK38212.1 - 0.0066 16.9 0.1 0.0069 16.8 0.1 1.2 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger zf-Di19 PF05605.12 KIK38212.1 - 0.025 14.9 2.6 0.029 14.7 2.0 1.4 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KIK38212.1 - 0.12 12.7 3.0 0.14 12.5 2.8 1.3 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KIK38212.1 - 0.78 10.3 13.6 1.9 9.1 2.9 2.5 2 1 0 2 2 2 0 Zinc-finger double domain zf-WRNIP1_ubi PF18279.1 KIK38212.1 - 2.8 8.8 6.5 3.1 8.6 1.4 2.6 1 1 1 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Nup188 PF10487.9 KIK38215.1 - 4.7e-45 153.9 0.0 1.1e-26 93.1 0.0 3.9 3 1 0 3 3 3 3 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 KIK38215.1 - 0.00041 19.3 0.2 0.0011 17.9 0.1 1.8 2 0 0 2 2 2 1 Nuclear pore protein NUP188 C-terminal domain Peptidase_M24 PF00557.24 KIK38216.1 - 3.9e-47 160.6 0.0 4.9e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Mgm101p PF06420.12 KIK38217.1 - 4.6e-88 293.1 0.0 5.8e-88 292.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 GCP_N_terminal PF17681.1 KIK38218.1 - 8e-39 134.1 0.0 1.3e-38 133.4 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KIK38218.1 - 6.8e-33 114.4 0.6 6.8e-33 114.4 0.6 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal VWA PF00092.28 KIK38219.1 - 0.00037 20.8 0.1 0.42 10.8 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain PCI PF01399.27 KIK38220.1 - 3.1e-13 50.1 0.0 5.8e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 PCI domain SEO_C PF14577.6 KIK38221.1 - 0.052 13.0 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 Sieve element occlusion C-terminus CNF1 PF05785.12 KIK38222.1 - 0.016 14.5 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Rho-activating domain of cytotoxic necrotizing factor UvrD_C_2 PF13538.6 KIK38223.1 - 0.00072 19.3 0.0 0.0015 18.3 0.0 1.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KIK38223.1 - 0.02 14.6 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.14 KIK38223.1 - 0.03 12.3 0.0 0.033 12.1 0.0 1.1 1 0 0 1 1 1 0 Helicase PIF1 PF05970.14 KIK38224.1 - 0.0017 17.6 0.1 0.0027 17.0 0.0 1.4 2 0 0 2 2 2 1 PIF1-like helicase DUF4597 PF15366.6 KIK38224.1 - 0.1 12.3 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) PIF1 PF05970.14 KIK38225.1 - 2.5e-07 30.2 0.4 2.6e-07 30.2 0.4 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIK38225.1 - 1.1e-05 25.2 0.2 1.3e-05 25.0 0.2 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK38225.1 - 5.8e-05 23.5 0.1 5.8e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KIK38225.1 - 0.00026 20.7 0.1 0.00031 20.4 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.6 KIK38225.1 - 0.00035 20.9 0.1 0.00043 20.6 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KIK38225.1 - 0.00063 19.6 0.1 0.00063 19.6 0.1 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Mg_chelatase PF01078.21 KIK38225.1 - 0.0019 17.6 0.3 0.002 17.5 0.3 1.0 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KIK38225.1 - 0.002 18.1 0.1 0.0025 17.8 0.1 1.1 1 0 0 1 1 1 1 NACHT domain MCM PF00493.23 KIK38225.1 - 0.0027 16.8 0.0 0.0027 16.8 0.0 1.1 1 0 0 1 1 1 1 MCM P-loop domain AAA_22 PF13401.6 KIK38225.1 - 0.0039 17.5 0.0 0.0045 17.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KIK38225.1 - 0.0081 16.2 0.1 0.009 16.0 0.1 1.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 KIK38225.1 - 0.009 16.5 0.1 0.0095 16.5 0.1 1.2 1 0 0 1 1 1 1 ABC transporter NB-ARC PF00931.22 KIK38225.1 - 0.019 14.2 0.1 0.021 14.0 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain SMC_N PF02463.19 KIK38225.1 - 0.032 13.7 0.0 0.032 13.7 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Parvo_NS1 PF01057.17 KIK38225.1 - 0.034 13.2 0.0 0.04 13.0 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.13 KIK38225.1 - 0.042 13.0 0.1 0.053 12.7 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_15 PF13175.6 KIK38225.1 - 0.042 13.6 0.0 0.043 13.5 0.0 1.0 1 0 0 1 1 1 0 AAA ATPase domain ABC_ATPase PF09818.9 KIK38225.1 - 0.056 12.2 0.2 0.063 12.1 0.2 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Sigma54_activat PF00158.26 KIK38225.1 - 0.06 13.0 0.1 0.06 13.0 0.1 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 KIK38225.1 - 0.066 13.6 0.1 0.081 13.4 0.1 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KIK38225.1 - 0.1 13.1 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.23 KIK38226.1 - 2.6e-64 217.2 1.6 2.8e-46 157.9 0.2 2.8 1 1 1 2 2 2 2 SNF2 family N-terminal domain HSA PF07529.13 KIK38226.1 - 6.7e-20 71.2 5.1 6.7e-20 71.2 5.1 2.8 3 0 0 3 3 3 1 HSA Helicase_C PF00271.31 KIK38226.1 - 3.9e-19 69.0 1.1 9.5e-19 67.8 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 KIK38226.1 - 5e-18 65.0 0.0 1.6e-17 63.3 0.0 1.9 1 0 0 1 1 1 1 Bromodomain QLQ PF08880.11 KIK38226.1 - 6.9e-13 48.1 0.0 2.7e-12 46.2 0.0 2.2 1 0 0 1 1 1 1 QLQ SnAC PF14619.6 KIK38226.1 - 1.1e-12 48.4 0.1 1.1e-12 48.4 0.1 3.9 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 KIK38226.1 - 0.00023 21.2 0.1 0.35 10.9 0.0 3.3 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit PriA_3primeBD PF17764.1 KIK38226.1 - 0.11 12.4 0.0 0.44 10.5 0.0 2.1 1 0 0 1 1 1 0 3′ DNA-binding domain (3′BD) DUF3383 PF11863.8 KIK38226.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) Ku PF02735.16 KIK38227.1 - 7.7e-27 94.3 0.0 1.4e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 KIK38227.1 - 1e-25 90.2 0.5 2.1e-25 89.2 0.0 1.8 2 0 0 2 2 2 1 Ku C terminal domain like Ku_N PF03731.15 KIK38227.1 - 9.3e-08 32.1 0.0 3.3e-07 30.3 0.0 2.0 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KIK38227.1 - 1.6e-06 28.5 0.0 4.1e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIK38227.1 - 0.00012 22.7 0.0 0.00043 20.9 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain Ku_C PF03730.14 KIK38227.1 - 0.0032 18.1 0.5 0.0032 18.1 0.5 2.2 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm UME PF08064.13 KIK38227.1 - 0.18 11.8 0.0 0.5 10.3 0.0 1.7 1 0 0 1 1 1 0 UME (NUC010) domain NOA36 PF06524.12 KIK38227.1 - 1.5 8.1 6.3 3.6 6.8 6.3 1.6 1 0 0 1 1 1 0 NOA36 protein SRP68 PF16969.5 KIK38228.1 - 2.3e-83 281.1 4.1 9e-82 275.9 0.6 2.0 2 0 0 2 2 2 2 RNA-binding signal recognition particle 68 Abi_C PF14355.6 KIK38228.1 - 0.065 13.4 0.1 13 5.9 0.0 2.7 2 0 0 2 2 2 0 Abortive infection C-terminus DUF4328 PF14219.6 KIK38228.1 - 0.13 11.8 0.1 0.3 10.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) ArsA_ATPase PF02374.15 KIK38229.1 - 2.8e-113 378.1 1.2 3.2e-113 377.9 1.2 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KIK38229.1 - 1.1e-13 51.5 0.1 5.3e-13 49.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KIK38229.1 - 8.2e-13 48.5 0.0 2.3e-12 47.1 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 KIK38229.1 - 8.3e-06 25.4 0.0 3.9e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 KIK38229.1 - 3.1e-05 23.6 0.1 7.2e-05 22.4 0.1 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 KIK38229.1 - 4.4e-05 23.0 4.0 0.00014 21.4 0.6 2.8 2 2 1 3 3 3 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 KIK38229.1 - 0.00011 21.9 0.6 0.0022 17.6 0.1 2.5 2 1 1 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 KIK38229.1 - 0.015 14.9 2.0 0.065 12.8 0.6 2.5 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KIK38229.1 - 0.027 14.2 0.0 0.081 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain VirC1 PF07015.11 KIK38229.1 - 0.048 13.0 0.1 0.11 11.8 0.1 1.6 1 1 0 1 1 1 0 VirC1 protein PhoH PF02562.16 KIK38229.1 - 0.085 12.3 0.0 0.21 11.0 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein UQ_con PF00179.26 KIK38230.1 - 2.4e-29 101.8 0.0 2.8e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIK38230.1 - 9.8e-05 22.1 0.0 0.0023 17.6 0.0 2.1 1 1 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KIK38230.1 - 0.011 15.6 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 UEV domain Trp_oprn_chp PF09534.10 KIK38230.1 - 0.2 11.4 0.0 0.24 11.2 0.0 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Porphobil_deam PF01379.20 KIK38231.1 - 9.4e-71 237.5 0.0 1.3e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KIK38231.1 - 6.2e-19 68.2 0.9 1.4e-18 67.0 0.2 1.9 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain WD40 PF00400.32 KIK38233.1 - 4.1e-42 141.3 25.3 1.5e-08 35.1 0.3 7.3 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38233.1 - 6.9e-22 77.6 2.8 0.0002 21.6 0.1 5.9 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK38233.1 - 8.6e-07 28.2 0.0 0.66 8.9 0.0 5.5 1 1 4 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK38233.1 - 1.4e-06 27.2 1.8 0.16 10.5 0.0 4.6 2 1 4 6 6 6 3 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KIK38233.1 - 0.00066 19.3 1.6 0.045 13.3 0.3 3.0 1 1 1 2 2 2 2 PQQ-like domain Nbas_N PF15492.6 KIK38233.1 - 0.00069 19.0 0.5 0.17 11.2 0.2 3.6 1 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal DUF5570 PF17731.1 KIK38233.1 - 0.001 19.2 1.6 5.5 7.1 0.0 4.0 2 1 2 4 4 4 2 Family of unknown function (DUF5570) PQQ_3 PF13570.6 KIK38233.1 - 0.003 18.0 0.1 8 7.1 0.0 4.3 4 0 0 4 4 4 1 PQQ-like domain Lactamase_B_5 PF14597.6 KIK38233.1 - 0.009 15.5 1.7 0.23 11.0 0.1 2.5 2 1 1 3 3 3 1 Metallo-beta-lactamase superfamily WD40_like PF17005.5 KIK38233.1 - 0.0094 15.3 0.0 2.9 7.1 0.0 3.4 4 0 0 4 4 4 1 WD40-like domain DUF4082 PF13313.6 KIK38233.1 - 0.36 10.9 1.3 21 5.1 0.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4082) ABC_membrane PF00664.23 KIK38234.1 - 2.9e-103 345.3 35.3 2.2e-52 178.4 11.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK38234.1 - 1.1e-68 230.0 0.0 2.7e-33 115.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIK38234.1 - 7.2e-13 48.5 5.2 6.7e-05 22.4 0.9 4.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIK38234.1 - 8.3e-08 32.8 1.8 0.0027 18.1 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 KIK38234.1 - 3.5e-07 29.4 2.9 0.01 14.7 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 KIK38234.1 - 8.2e-07 28.5 0.0 0.011 15.0 0.0 3.1 4 0 0 4 4 4 2 Zeta toxin AAA_29 PF13555.6 KIK38234.1 - 9.4e-07 28.5 3.0 0.0041 16.8 0.7 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KIK38234.1 - 7.5e-06 26.0 0.0 0.18 11.6 0.0 3.9 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIK38234.1 - 1.1e-05 25.3 0.0 0.023 14.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIK38234.1 - 2e-05 24.6 0.1 0.22 11.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KIK38234.1 - 5.4e-05 23.5 2.0 0.056 13.7 0.1 3.5 3 1 0 3 3 2 1 AAA domain AAA_25 PF13481.6 KIK38234.1 - 0.00013 21.6 1.2 0.23 11.0 0.1 3.7 4 0 0 4 4 3 1 AAA domain AAA_23 PF13476.6 KIK38234.1 - 0.00033 21.2 0.2 0.47 10.9 0.4 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KIK38234.1 - 0.0008 19.8 0.3 18 5.8 0.0 4.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 KIK38234.1 - 0.0011 18.3 0.1 0.49 9.5 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_30 PF13604.6 KIK38234.1 - 0.0028 17.4 0.5 4.9 6.8 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KIK38234.1 - 0.0036 17.3 0.2 1.9 8.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 KIK38234.1 - 0.0052 17.0 2.7 5.2 7.4 0.3 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KIK38234.1 - 0.0078 16.4 0.0 5.1 7.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KIK38234.1 - 0.0078 15.7 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 KIK38234.1 - 0.013 16.0 0.0 2 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KIK38234.1 - 0.013 15.4 0.1 2.7 7.9 0.1 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_28 PF13521.6 KIK38234.1 - 0.016 15.4 2.4 0.77 10.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KIK38234.1 - 0.017 15.5 0.1 5 7.6 0.0 3.6 3 0 0 3 3 3 0 RNA helicase PRK PF00485.18 KIK38234.1 - 0.022 14.5 0.0 0.95 9.2 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.15 KIK38234.1 - 0.057 13.3 0.0 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 KIK38234.1 - 0.064 13.3 0.1 9.1 6.4 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 KIK38234.1 - 0.091 11.9 0.0 3.5 6.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 KIK38234.1 - 0.16 11.7 0.3 23 4.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KIK38234.1 - 0.36 10.9 3.6 15 5.6 0.3 3.1 3 1 0 3 3 2 0 Helicase HerA, central domain DUF3325 PF11804.8 KIK38234.1 - 5.5 7.2 9.8 5.8 7.1 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) WD40 PF00400.32 KIK38237.1 - 3.4e-43 144.8 33.4 2.3e-08 34.6 2.7 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38237.1 - 5.9e-21 74.6 6.3 0.00023 21.4 0.1 5.5 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK38237.1 - 8.4e-11 41.2 2.1 0.0034 16.1 0.5 4.3 3 2 0 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK38237.1 - 4.9e-08 32.3 0.2 2.6 6.9 0.1 6.0 1 1 4 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK38237.1 - 0.00044 20.1 0.0 0.59 10.1 0.0 4.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat PQQ PF01011.21 KIK38237.1 - 0.027 14.4 0.1 23 5.1 0.0 4.4 4 0 0 4 4 4 0 PQQ enzyme repeat WD40_like PF17005.5 KIK38237.1 - 0.036 13.4 0.0 12 5.1 0.0 3.0 2 1 1 3 3 3 0 WD40-like domain Nbas_N PF15492.6 KIK38237.1 - 0.045 13.1 5.2 0.9 8.8 0.1 4.0 1 1 3 5 5 5 0 Neuroblastoma-amplified sequence, N terminal DUF5122 PF17164.4 KIK38237.1 - 0.38 11.1 1.9 28 5.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller Proteasome_A_N PF10584.9 KIK38237.1 - 1.5 8.6 3.1 32 4.3 0.0 4.0 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Frag1 PF10277.9 KIK38238.1 - 0.043 13.3 4.8 0.06 12.9 3.4 2.2 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family Pox_A14 PF05767.12 KIK38238.1 - 0.045 13.9 1.1 0.13 12.4 1.1 1.9 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 MIG-14_Wnt-bd PF06664.12 KIK38238.1 - 0.071 12.3 13.9 0.22 10.7 13.9 1.9 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion UcrQ PF02939.16 KIK38238.1 - 0.14 12.2 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 UcrQ family DUF4519 PF15012.6 KIK38238.1 - 0.2 11.9 1.7 22 5.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Baculo_E56 PF04639.12 KIK38238.1 - 0.24 10.7 1.8 0.37 10.0 1.8 1.3 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope DUF3290 PF11694.8 KIK38238.1 - 0.61 10.0 5.2 0.69 9.9 3.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3290) Borrelia_orfX PF04160.12 KIK38241.1 - 0.067 13.2 9.4 0.043 13.8 6.1 2.0 2 0 0 2 2 2 0 Orf-X protein DUF4519 PF15012.6 KIK38241.1 - 1.1 9.5 3.6 27 5.0 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) WD40 PF00400.32 KIK38242.1 - 2.7e-21 75.5 9.1 2e-07 31.6 0.1 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38242.1 - 2.8e-08 34.0 0.1 0.05 13.9 0.0 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK38242.1 - 0.0003 20.7 0.1 0.19 11.7 0.1 3.3 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK38242.1 - 0.001 18.1 0.1 2.1 7.3 0.0 2.8 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 KIK38242.1 - 0.028 14.1 0.6 32 4.3 0.0 3.5 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Ago_hook PF10427.9 KIK38242.1 - 0.038 14.5 1.6 0.055 14.0 1.6 1.4 1 1 0 1 1 1 0 Argonaute hook MMS1_N PF10433.9 KIK38242.1 - 0.043 12.4 0.0 0.054 12.1 0.0 1.1 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF5122 PF17164.4 KIK38242.1 - 0.08 13.2 0.1 6.5 7.1 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller Nup160 PF11715.8 KIK38242.1 - 0.13 10.9 2.2 2.6 6.6 0.1 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK38242.1 - 0.19 11.0 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 WD40-like domain SNF2_N PF00176.23 KIK38243.1 - 2.4e-44 151.5 0.0 4.6e-44 150.6 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.25 KIK38243.1 - 1.4e-06 28.0 8.6 2.8e-06 27.1 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK38243.1 - 2.3e-06 27.4 8.9 3.9e-06 26.6 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK38243.1 - 2.8e-06 27.6 10.9 5.7e-06 26.6 10.9 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KIK38243.1 - 3.3e-05 23.6 8.0 6.3e-05 22.8 8.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KIK38243.1 - 8.6e-05 22.3 9.5 0.00016 21.4 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK38243.1 - 0.00033 20.6 10.5 0.00058 19.8 10.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KIK38243.1 - 0.0013 19.0 5.4 0.0034 17.6 5.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Helicase_C PF00271.31 KIK38243.1 - 0.017 15.4 0.0 0.06 13.7 0.0 2.0 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-ANAPC11 PF12861.7 KIK38243.1 - 0.058 13.4 4.6 0.18 11.8 4.6 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger End3 PF12761.7 KIK38243.1 - 0.087 13.0 6.4 0.27 11.4 6.4 1.8 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 zf-RING_UBOX PF13445.6 KIK38243.1 - 0.093 12.8 5.5 0.3 11.1 5.6 1.9 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KIK38243.1 - 0.41 10.3 7.8 0.85 9.3 7.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KIK38243.1 - 1.3 9.3 8.9 2.5 8.3 8.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Dict-STAT-coil PF09267.10 KIK38243.1 - 5 7.5 7.3 0.4 11.1 0.1 2.6 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil Myb_DNA-binding PF00249.31 KIK38244.1 - 7.9e-19 67.6 0.6 3.9e-10 39.7 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK38244.1 - 3.1e-13 49.7 1.5 2.1e-05 24.7 0.0 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 KIK38244.1 - 0.00014 21.8 0.1 0.71 9.9 0.0 2.4 2 0 0 2 2 2 2 SLIDE PCI PF01399.27 KIK38245.1 - 5.7e-10 39.6 0.1 4.5e-09 36.8 0.0 2.3 3 0 0 3 3 3 1 PCI domain Med16 PF11635.8 KIK38245.1 - 0.011 13.8 0.0 0.015 13.3 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 16 DUF3562 PF12085.8 KIK38245.1 - 0.086 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) Cofilin_ADF PF00241.20 KIK38246.1 - 2.2e-40 137.2 0.1 2.4e-40 137.1 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein F-box-like PF12937.7 KIK38248.1 - 1e-05 25.3 0.6 3.4e-05 23.6 0.6 2.0 1 0 0 1 1 1 1 F-box-like Trns_repr_metal PF02583.17 KIK38248.1 - 0.062 13.7 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor LRR_4 PF12799.7 KIK38248.1 - 4.4 7.9 18.0 19 5.8 0.6 5.3 3 3 4 7 7 7 0 Leucine Rich repeats (2 copies) ICMT PF04140.14 KIK38249.1 - 4.9e-14 52.5 0.0 1.2e-12 48.1 0.1 2.3 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK38249.1 - 2.6e-10 40.6 0.7 8.6e-10 39.0 0.2 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIK38249.1 - 1.6e-06 27.2 0.2 2.2e-06 26.7 0.2 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KIK38249.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) STE3 PF02076.15 KIK38250.1 - 5.1e-114 380.4 18.8 6e-114 380.1 18.8 1.0 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.15 KIK38253.1 - 2e-64 217.6 20.1 2.4e-64 217.3 20.1 1.0 1 0 0 1 1 1 1 Pheromone A receptor Cep57_CLD PF14073.6 KIK38254.1 - 0.013 15.5 0.9 0.022 14.8 0.9 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Syntaxin-6_N PF09177.11 KIK38254.1 - 0.049 14.2 0.3 0.13 12.9 0.3 1.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF745 PF05335.13 KIK38254.1 - 0.11 12.2 1.0 0.17 11.6 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF4407 PF14362.6 KIK38254.1 - 0.12 11.7 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF148 PF02520.17 KIK38254.1 - 0.13 12.4 0.2 0.22 11.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF148 DUF812 PF05667.11 KIK38254.1 - 0.15 10.9 3.1 0.21 10.4 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4988 PF16378.5 KIK38254.1 - 0.15 11.7 0.2 0.28 10.8 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function FapA PF03961.13 KIK38254.1 - 0.24 10.0 0.3 0.32 9.5 0.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A BatA PF07584.11 KIK38254.1 - 0.44 10.9 3.1 1.1 9.7 1.7 2.5 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal ABC_tran_CTD PF16326.5 KIK38254.1 - 1.1 9.6 7.6 6.1 7.2 0.4 2.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain STE3 PF02076.15 KIK38255.1 - 2.8e-91 305.7 25.8 3.2e-91 305.5 25.8 1.0 1 0 0 1 1 1 1 Pheromone A receptor Pheromone PF08015.11 KIK38256.1 - 4.4e-06 27.7 0.1 5.7e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Fungal mating-type pheromone FXMRP1_C_core PF12235.8 KIK38259.1 - 0.6 10.8 12.2 15 6.2 8.9 3.0 2 1 0 2 2 2 0 Fragile X-related 1 protein core C terminal CTI PF06934.11 KIK38260.1 - 0.15 10.5 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) VTC PF09359.10 KIK38264.1 - 1.1e-96 323.4 0.0 2.7e-96 322.2 0.0 1.6 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 KIK38264.1 - 2.8e-18 67.0 16.7 1.5e-06 28.4 1.8 3.6 2 1 2 4 4 4 3 SPX domain DUF202 PF02656.15 KIK38264.1 - 1.3e-10 41.6 4.0 2.5e-10 40.6 4.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Clc-like PF07062.12 KIK38264.1 - 0.0084 15.6 0.4 0.015 14.8 0.4 1.3 1 0 0 1 1 1 1 Clc-like Herpes_UL25 PF01499.16 KIK38264.1 - 0.052 12.1 0.6 0.08 11.5 0.6 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family FliE PF02049.18 KIK38264.1 - 0.22 11.7 1.5 0.27 11.4 0.2 1.8 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE Polysacc_synt_C PF14667.6 KIK38264.1 - 0.43 10.7 4.4 0.68 10.0 4.4 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Cwf_Cwc_15 PF04889.12 KIK38264.1 - 2.4 7.8 13.3 5.3 6.7 13.3 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.32 KIK38268.1 - 8.5e-29 99.2 3.7 2.1e-07 31.5 0.1 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38268.1 - 9.3e-06 25.9 0.3 2.9 8.3 0.0 4.6 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK38268.1 - 0.00012 20.9 0.3 0.061 12.0 0.0 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK38268.1 - 0.00024 20.5 0.1 0.0023 17.3 0.0 2.3 2 1 1 3 3 3 2 WD40-like domain DUF4210 PF13915.6 KIK38269.1 - 0.097 13.3 0.1 0.15 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4210) Pkinase_fungal PF17667.1 KIK38270.1 - 5.1e-37 127.6 0.0 5.6e-24 84.7 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIK38270.1 - 3.7e-05 23.2 0.0 0.0005 19.5 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KIK38270.1 - 0.029 14.3 0.1 0.045 13.7 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family VSP PF03302.13 KIK38273.1 - 0.00011 21.3 3.1 0.00015 20.8 3.1 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF3149 PF11346.8 KIK38273.1 - 0.029 14.0 1.5 0.057 13.0 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) PTPlike_phytase PF14566.6 KIK38274.1 - 5.9e-139 458.6 0.0 8e-47 159.2 0.0 4.3 5 0 0 5 5 5 3 Inositol hexakisphosphate Y_phosphatase PF00102.27 KIK38274.1 - 0.00085 19.0 0.0 1 8.9 0.0 3.1 3 0 0 3 3 3 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KIK38274.1 - 0.013 15.5 0.0 3.3 7.6 0.0 3.4 3 0 0 3 3 3 0 Tyrosine phosphatase family DSPc PF00782.20 KIK38274.1 - 0.014 15.2 0.0 4.5 7.1 0.0 3.3 3 0 0 3 3 3 0 Dual specificity phosphatase, catalytic domain Cnn_1N PF07989.11 KIK38274.1 - 0.16 12.1 0.8 15 5.9 0.2 3.5 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 GrpB PF04229.14 KIK38274.1 - 0.48 10.6 3.1 13 5.9 0.1 3.2 3 0 0 3 3 3 0 GrpB protein p450 PF00067.22 KIK38276.1 - 2e-77 260.9 0.0 2.6e-77 260.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2550 PF10739.9 KIK38276.1 - 0.43 10.6 0.1 0.43 10.6 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2550) Glyco_trans_1_3 PF13528.6 KIK38277.1 - 0.00091 18.6 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 1 YTH PF04146.15 KIK38278.1 - 9.1e-62 207.9 0.4 2.7e-61 206.3 0.4 1.9 1 1 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 KIK38278.1 - 3.3e-05 23.6 0.0 0.0067 16.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIK38278.1 - 0.082 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif ORC_WH_C PF18137.1 KIK38284.1 - 0.66 10.0 5.0 9.3 6.3 2.2 2.4 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal WD40 PF00400.32 KIK38285.1 - 2.5e-08 34.5 5.3 0.082 13.8 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat CPSF_A PF03178.15 KIK38285.1 - 0.0019 17.6 0.0 0.01 15.1 0.0 2.0 1 1 0 1 1 1 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 KIK38285.1 - 0.12 12.7 0.2 39 4.6 0.0 3.9 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF2781 PF10914.8 KIK38286.1 - 4e-43 147.4 10.4 4.6e-43 147.1 10.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) PIG-P PF08510.12 KIK38286.1 - 1.4 8.9 5.3 0.21 11.5 0.4 2.0 2 0 0 2 2 2 0 PIG-P Ribosomal_L37ae PF01780.19 KIK38287.1 - 3.5e-42 142.4 11.3 3.9e-42 142.2 11.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KIK38287.1 - 0.00058 19.9 3.2 0.00082 19.5 3.2 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 KIK38287.1 - 0.0013 18.7 2.0 0.0021 18.0 2.0 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Sgf11 PF08209.11 KIK38287.1 - 0.046 13.3 0.5 0.41 10.2 0.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DUF1451 PF07295.11 KIK38287.1 - 0.046 13.8 0.8 0.067 13.2 0.8 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-BED PF02892.15 KIK38287.1 - 0.069 13.2 6.2 1.5 8.9 1.2 2.2 1 1 1 2 2 2 0 BED zinc finger C1_2 PF03107.16 KIK38287.1 - 0.29 11.5 3.0 1.2 9.6 3.0 1.8 1 1 0 1 1 1 0 C1 domain zf-Sec23_Sec24 PF04810.15 KIK38287.1 - 1.1 9.3 6.2 5.6 7.1 0.2 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-H2C2_2 PF13465.6 KIK38287.1 - 1.3 9.6 5.8 2.3 8.8 0.8 2.2 1 1 1 2 2 2 0 Zinc-finger double domain zf-CCCH PF00642.24 KIK38288.1 - 9e-11 41.4 19.5 0.00018 21.3 0.7 4.6 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIK38288.1 - 0.037 14.1 26.6 1.7 8.8 0.3 5.8 5 1 0 5 5 5 0 Zinc finger domain zf-CCCH_3 PF15663.5 KIK38288.1 - 0.07 13.4 15.9 0.033 14.4 3.5 3.5 1 1 2 3 3 3 0 Zinc-finger containing family Torus PF16131.5 KIK38288.1 - 0.41 11.4 23.5 0.38 11.5 0.8 4.6 1 1 4 5 5 5 0 Torus domain zf-CCCH_4 PF18044.1 KIK38288.1 - 2.6 7.9 28.0 0.23 11.3 0.7 5.5 6 0 0 6 6 6 0 CCCH-type zinc finger PAT1 PF09770.9 KIK38290.1 - 6.6e-110 368.8 50.8 8.8e-97 325.4 33.8 2.6 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 MotB_plug PF13677.6 KIK38290.1 - 1.3 8.7 3.8 17 5.1 0.0 3.6 4 0 0 4 4 4 0 Membrane MotB of proton-channel complex MotA/MotB hDGE_amylase PF14701.6 KIK38291.1 - 2.4e-156 521.3 0.0 3e-156 520.9 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KIK38291.1 - 5.7e-120 400.7 0.0 9e-120 400.1 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KIK38291.1 - 1.2e-76 257.7 0.0 1.7e-76 257.2 0.0 1.2 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KIK38291.1 - 1.1e-21 76.7 0.0 2.3e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Zds_C PF08632.10 KIK38294.1 - 1.3e-28 98.5 0.1 3.7e-28 97.0 0.1 1.8 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term MOZART1 PF12554.8 KIK38295.1 - 5.1e-24 83.8 0.1 5.8e-24 83.6 0.1 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated MOZART2 PF12926.7 KIK38295.1 - 0.024 14.3 0.0 0.027 14.1 0.0 1.0 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated Tma16 PF11176.8 KIK38296.1 - 1.5e-46 157.9 1.7 1.8e-46 157.6 1.7 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Pkinase PF00069.25 KIK38297.1 - 1.3e-67 227.9 0.0 2e-67 227.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK38297.1 - 3.2e-37 128.2 0.0 5e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 KIK38297.1 - 7.2e-06 25.7 0.0 2.3e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Haspin_kinase PF12330.8 KIK38297.1 - 0.0056 15.7 0.1 0.0093 14.9 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KIK38297.1 - 0.017 14.5 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KIK38297.1 - 0.018 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK38297.1 - 0.06 13.3 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIK38297.1 - 0.082 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase DNA_ligase_A_M PF01068.21 KIK38298.1 - 6.5e-54 182.7 0.1 1e-53 182.0 0.1 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KIK38298.1 - 4e-41 141.2 0.0 7.3e-41 140.4 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KIK38298.1 - 2.2e-15 57.1 0.0 1e-14 54.9 0.0 2.3 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.5 KIK38298.1 - 7.8e-15 55.1 0.1 2.9e-13 50.0 0.0 2.7 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 KIK38298.1 - 4.6e-13 49.8 0.1 8.9e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 KIK38298.1 - 1.4e-05 25.4 0.0 4.2e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KIK38298.1 - 0.049 13.9 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 KIK38298.1 - 0.17 11.8 0.0 0.45 10.5 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain HMG_box PF00505.19 KIK38299.1 - 3.8e-22 78.5 8.0 4.2e-13 49.5 1.3 3.1 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK38299.1 - 9.6e-13 48.5 4.3 3.8e-08 33.8 0.6 2.7 2 0 0 2 2 2 2 HMG-box domain MGC-24 PF05283.11 KIK38299.1 - 6.3 7.2 9.2 3.5 8.1 6.6 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3328 PF11807.8 KIK38300.1 - 6.3e-54 183.1 0.0 7.7e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KIK38301.1 - 5.2e-55 186.6 0.6 6.9e-55 186.2 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) SHIRT PF18655.1 KIK38304.1 - 0.00045 20.8 7.3 0.17 12.5 1.4 3.5 1 1 2 3 3 3 3 SHIRT domain YfiO PF13525.6 KIK38304.1 - 0.00074 19.3 13.6 0.2 11.4 0.4 4.0 1 1 3 4 4 4 3 Outer membrane lipoprotein DUF2535 PF10751.9 KIK38304.1 - 1.7 9.2 26.5 28 5.3 0.4 7.6 2 2 5 7 7 7 0 Protein of unknown function (DUF2535) GCP_N_terminal PF17681.1 KIK38305.1 - 6.3e-62 209.9 0.0 1.1e-61 209.1 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KIK38305.1 - 1e-58 199.3 5.5 1e-58 199.3 5.5 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Imm2 PF14426.6 KIK38305.1 - 0.33 11.0 2.1 30 4.8 0.1 3.7 3 0 0 3 3 3 0 Immunity protein Imm2 S4 PF01479.25 KIK38306.1 - 1.2e-08 34.5 0.0 2.2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 KIK38306.1 - 0.065 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 S4 domain Ferric_reduct PF01794.19 KIK38307.1 - 6.5e-21 74.7 5.4 1.8e-20 73.3 5.4 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KIK38307.1 - 3.4e-11 43.5 0.0 1e-08 35.5 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KIK38307.1 - 3.4e-11 43.2 0.0 1.1e-10 41.6 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 KIK38307.1 - 0.082 13.6 0.0 0.92 10.2 0.0 2.6 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain DAO PF01266.24 KIK38308.1 - 4.3e-20 72.6 0.3 5.9e-20 72.1 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK38309.1 - 1.3e-51 175.6 0.0 1.8e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK38309.1 - 5e-09 36.6 0.0 2.5e-08 34.4 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KIK38309.1 - 0.048 14.1 0.4 3.2 8.2 0.0 3.3 2 1 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 KIK38309.1 - 0.11 11.7 0.1 23 4.1 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF3072 PF11272.8 KIK38309.1 - 0.71 9.8 4.7 0.54 10.2 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) RGS PF00615.19 KIK38312.1 - 2.1e-09 37.7 0.5 0.00018 21.8 0.2 2.5 2 1 0 2 2 2 2 Regulator of G protein signaling domain L51_S25_CI-B8 PF05047.16 KIK38313.1 - 7.4e-13 48.2 0.0 1e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RE_XcyI PF09571.10 KIK38313.1 - 0.1 11.8 0.0 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 XcyI restriction endonuclease DUF3328 PF11807.8 KIK38316.1 - 2e-52 178.2 0.0 2.4e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) HnRNP_M PF11532.8 KIK38319.1 - 0.16 12.2 0.8 22 5.4 0.1 2.3 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein M ESCRT-II PF05871.12 KIK38320.1 - 2.2e-26 92.8 0.1 2.9e-26 92.4 0.1 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit NUFIP1 PF10453.9 KIK38321.1 - 0.066 13.1 0.4 0.11 12.4 0.4 1.3 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) MMR_HSR1 PF01926.23 KIK38322.1 - 5.9e-05 23.1 0.0 0.00013 22.1 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 KIK38322.1 - 0.00075 19.0 0.0 0.0017 17.8 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KIK38322.1 - 0.0065 16.7 0.0 0.017 15.3 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KIK38322.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein GTP_EFTU PF00009.27 KIK38322.1 - 0.014 15.0 0.0 2 7.9 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Septin PF00735.18 KIK38322.1 - 0.037 13.3 0.0 1.5 8.0 0.0 2.0 2 0 0 2 2 2 0 Septin G-alpha PF00503.20 KIK38322.1 - 0.059 12.5 0.0 0.35 10.0 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit ATP-synt_ab PF00006.25 KIK38322.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain FeoB_N PF02421.18 KIK38322.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 KIK38322.1 - 0.15 11.8 0.1 0.49 10.1 0.0 1.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ADSL_C PF10397.9 KIK38322.1 - 0.17 12.4 0.0 0.35 11.5 0.0 1.5 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus DNA_binding_1 PF01035.20 KIK38323.1 - 2.7e-25 88.3 0.0 4e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Peptidase_S10 PF00450.22 KIK38324.1 - 9.5e-70 236.1 0.2 2e-69 235.1 0.2 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase WD40 PF00400.32 KIK38326.1 - 2.9e-28 97.5 6.1 4.2e-06 27.4 0.2 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38326.1 - 4.4e-13 49.3 0.0 0.018 15.3 0.0 4.3 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK38326.1 - 3e-05 23.8 0.4 1.1 9.3 0.0 3.6 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK38326.1 - 0.00057 19.3 0.0 0.71 9.1 0.0 3.6 4 1 1 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 KIK38326.1 - 0.057 12.4 0.0 4.2 6.2 0.0 2.4 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KIK38328.1 - 5.7e-28 96.6 10.9 6.7e-06 26.7 0.0 8.1 7 0 0 7 7 7 6 WD domain, G-beta repeat HET PF06985.11 KIK38328.1 - 4.5e-11 43.3 2.5 6.3e-09 36.3 0.1 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ANAPC4_WD40 PF12894.7 KIK38328.1 - 1.1e-09 38.4 1.2 0.18 12.1 0.0 5.1 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 KIK38328.1 - 2.9e-05 23.8 9.1 10 6.5 0.1 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat Ge1_WD40 PF16529.5 KIK38328.1 - 0.00021 20.3 0.0 0.041 12.8 0.0 2.8 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_1 PF00515.28 KIK38328.1 - 0.00023 20.8 4.8 2.1 8.3 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat RPN7 PF10602.9 KIK38328.1 - 0.0044 16.7 1.1 1.2 8.8 0.0 2.9 2 1 1 3 3 3 1 26S proteasome subunit RPN7 eIF2A PF08662.11 KIK38328.1 - 0.0071 16.2 0.0 0.37 10.6 0.0 2.8 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A phiKZ_IP PF12699.7 KIK38328.1 - 0.0082 15.3 0.0 3.2 6.8 0.0 2.5 2 0 0 2 2 2 2 phiKZ-like phage internal head proteins PD40 PF07676.12 KIK38328.1 - 0.015 15.2 0.1 1.7 8.6 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF3856 PF12968.7 KIK38328.1 - 0.019 15.0 0.2 4.1 7.5 0.0 3.7 4 0 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_14 PF13428.6 KIK38328.1 - 0.06 14.2 6.5 13 6.9 0.1 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK38328.1 - 0.18 11.5 1.3 3.4 7.4 0.1 3.6 4 0 0 4 4 4 0 TPR repeat UbiA PF01040.18 KIK38329.1 - 9.7e-11 41.4 7.2 5.9e-10 38.9 1.3 2.1 2 0 0 2 2 2 2 UbiA prenyltransferase family MFS_1 PF07690.16 KIK38330.1 - 9.3e-41 139.9 41.4 9.3e-41 139.9 41.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK38330.1 - 6e-06 25.4 9.8 6e-06 25.4 9.8 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 KIK38330.1 - 0.0022 16.4 2.5 0.0042 15.5 2.5 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector DUF5392 PF17370.2 KIK38330.1 - 0.2 11.7 0.0 0.54 10.3 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5392) E1-E2_ATPase PF00122.20 KIK38330.1 - 4.7 6.7 5.5 0.56 9.7 0.4 2.1 2 0 0 2 2 2 0 E1-E2 ATPase WD40 PF00400.32 KIK38333.1 - 2.6e-13 50.2 0.0 4.8e-07 30.4 0.0 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38333.1 - 3e-05 24.2 0.0 0.00033 20.9 0.0 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK38333.1 - 0.016 14.2 0.0 0.97 8.3 0.0 2.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KIK38339.1 - 6.8e-49 162.8 16.6 1.4e-07 32.1 0.4 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38339.1 - 1.9e-23 82.6 0.4 0.00054 20.2 0.1 6.6 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK38339.1 - 2.7e-12 46.3 1.2 0.02 13.9 0.0 6.0 1 1 4 6 6 6 5 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK38339.1 - 2.2e-06 26.6 2.8 0.18 10.4 0.1 4.2 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK38339.1 - 3e-06 26.8 2.4 5.3 6.3 0.0 5.6 1 1 5 6 6 6 2 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.6 KIK38339.1 - 8.1e-06 25.6 0.8 0.0029 17.2 0.3 2.7 1 1 2 3 3 3 2 PQQ-like domain WD40_like PF17005.5 KIK38339.1 - 4.9e-05 22.8 0.0 0.41 9.9 0.0 3.3 2 1 1 3 3 3 2 WD40-like domain eIF2A PF08662.11 KIK38339.1 - 0.00012 22.0 0.5 1.6 8.5 0.0 3.2 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KIK38339.1 - 0.00048 18.8 0.1 0.0013 17.4 0.1 1.5 1 1 0 1 1 1 1 Cytochrome D1 heme domain PD40 PF07676.12 KIK38339.1 - 0.0027 17.6 11.2 9.8 6.3 0.0 6.8 8 0 0 8 8 7 2 WD40-like Beta Propeller Repeat PQQ PF01011.21 KIK38339.1 - 0.0074 16.2 0.0 21 5.3 0.0 4.9 5 0 0 5 5 5 0 PQQ enzyme repeat DUF5046 PF16465.5 KIK38339.1 - 0.082 12.3 0.1 0.45 9.9 0.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5046) WD40 PF00400.32 KIK38342.1 - 1.8e-53 177.3 16.4 8.9e-08 32.7 0.7 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38342.1 - 1.7e-25 89.1 1.9 0.0011 19.2 0.1 6.8 1 1 6 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK38342.1 - 4.5e-15 55.4 0.4 0.035 13.1 0.0 6.2 1 1 5 6 6 6 5 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK38342.1 - 2.7e-09 37.2 0.1 0.021 14.7 0.0 3.5 1 1 4 5 5 5 5 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KIK38342.1 - 1.7e-08 34.1 1.5 0.45 9.8 0.0 4.8 1 1 5 6 6 6 3 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK38342.1 - 7e-08 32.1 0.0 0.02 14.3 0.0 3.7 2 2 2 4 4 4 2 WD40-like domain Nup160 PF11715.8 KIK38342.1 - 2.3e-07 29.9 6.1 0.21 10.2 0.1 4.6 2 1 3 5 5 5 3 Nucleoporin Nup120/160 PD40 PF07676.12 KIK38342.1 - 2.8e-06 27.1 2.5 8.8 6.4 0.0 6.4 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KIK38342.1 - 1.2e-05 24.1 0.2 0.00031 19.4 0.0 2.8 2 1 0 2 2 2 1 Cytochrome D1 heme domain BBS2_Mid PF14783.6 KIK38342.1 - 0.00016 21.7 1.0 0.26 11.3 0.0 3.3 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region SGL PF08450.12 KIK38342.1 - 0.0002 21.0 0.3 0.66 9.5 0.1 2.7 1 1 2 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Frtz PF11768.8 KIK38342.1 - 0.00055 18.4 0.0 0.4 8.9 0.0 3.0 3 0 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 KIK38342.1 - 0.0029 16.4 2.2 0.68 8.6 0.1 4.0 1 1 1 3 3 3 1 Nup133 N terminal like IKI3 PF04762.12 KIK38342.1 - 0.0048 15.0 1.3 0.018 13.1 1.2 2.1 1 1 0 1 1 1 1 IKI3 family PQQ_3 PF13570.6 KIK38342.1 - 0.16 12.5 3.2 9.5 6.9 0.1 4.6 4 2 1 5 5 5 0 PQQ-like domain DDE_Tnp_4 PF13359.6 KIK38344.1 - 5.5e-06 26.1 0.1 5.9e-06 26.0 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KIK38344.1 - 0.00029 20.5 0.1 0.00031 20.4 0.1 1.0 1 0 0 1 1 1 1 Plant transposon protein TB2_DP1_HVA22 PF03134.19 KIK38344.1 - 0.065 13.2 0.0 0.074 13.0 0.0 1.1 1 0 0 1 1 1 0 TB2/DP1, HVA22 family DDE_Tnp_4 PF13359.6 KIK38345.1 - 1.4e-22 80.1 0.0 2.3e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KIK38345.1 - 1.5e-05 24.7 0.0 2.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain WD40 PF00400.32 KIK38346.1 - 7.1e-47 156.4 13.7 4.8e-07 30.4 0.1 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38346.1 - 2e-23 82.5 0.2 0.0012 19.1 0.0 6.3 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK38346.1 - 1.4e-10 40.6 1.1 0.22 10.4 0.0 5.3 3 2 3 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK38346.1 - 6.3e-07 29.5 0.0 0.0081 16.1 0.0 2.9 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK38346.1 - 4.1e-06 26.6 2.2 6.5 6.8 0.0 6.9 8 0 0 8 8 8 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK38346.1 - 6.9e-06 25.6 0.2 0.57 9.5 0.0 4.5 2 1 4 6 6 6 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK38346.1 - 1.3e-05 24.1 1.8 0.47 9.0 0.0 4.2 2 1 2 4 4 4 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KIK38346.1 - 2.8e-05 23.8 3.0 0.0049 16.5 2.9 2.8 1 1 0 1 1 1 1 PQQ-like domain WD40_like PF17005.5 KIK38346.1 - 0.013 14.8 0.0 1.1 8.6 0.0 3.0 2 2 0 2 2 2 0 WD40-like domain Frtz PF11768.8 KIK38346.1 - 0.024 13.0 0.0 5.3 5.2 0.0 2.8 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Gmad1 PF10647.9 KIK38346.1 - 0.043 13.6 1.3 2.5 7.8 0.1 2.7 3 0 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain IKI3 PF04762.12 KIK38346.1 - 0.054 11.5 0.9 0.95 7.4 0.1 2.4 1 1 0 2 2 2 0 IKI3 family Cytochrom_D1 PF02239.16 KIK38346.1 - 0.085 11.4 0.1 1.4 7.3 0.0 2.2 1 1 2 3 3 3 0 Cytochrome D1 heme domain WD40 PF00400.32 KIK38348.1 - 3.2e-46 154.3 14.2 3.6e-07 30.8 0.1 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38348.1 - 2.4e-22 79.0 0.3 0.0014 18.9 0.0 6.2 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK38348.1 - 4.3e-10 39.1 0.1 0.64 8.9 0.0 5.6 2 2 4 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK38348.1 - 8.1e-06 24.7 3.6 1.4 7.5 0.0 4.3 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK38348.1 - 8.2e-06 25.3 0.2 0.27 10.5 0.0 4.1 2 1 4 6 6 6 2 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 KIK38348.1 - 2.2e-05 24.4 0.0 0.083 12.8 0.0 3.5 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK38348.1 - 0.00024 20.9 8.3 8.2 6.5 0.0 6.9 8 0 0 8 8 8 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 KIK38348.1 - 0.00042 20.0 2.2 0.14 11.7 0.5 2.9 2 1 0 2 2 2 2 PQQ-like domain Cytochrom_D1 PF02239.16 KIK38348.1 - 0.00072 18.2 0.0 0.0075 14.8 0.0 2.2 1 1 0 2 2 2 1 Cytochrome D1 heme domain Frtz PF11768.8 KIK38348.1 - 0.073 11.4 0.0 16 3.6 0.0 3.0 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Pkinase PF00069.25 KIK38349.1 - 2.2e-39 135.4 0.0 3.3e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK38349.1 - 4e-18 65.6 0.0 4.7e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK38349.1 - 0.00017 20.5 0.0 0.00025 20.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIK38349.1 - 0.00059 19.3 0.0 0.00092 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIK38349.1 - 0.025 13.9 0.0 0.068 12.5 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 KIK38349.1 - 0.086 11.8 0.2 0.13 11.1 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF2027 PF09640.10 KIK38349.1 - 0.16 11.6 0.0 0.4 10.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2027) WD40 PF00400.32 KIK38353.1 - 3.7e-48 160.5 13.7 1.4e-07 32.1 0.5 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38353.1 - 2.9e-22 78.8 0.1 0.00019 21.7 0.1 6.5 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK38353.1 - 2.6e-09 36.5 0.7 0.44 9.5 0.0 5.9 1 1 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KIK38353.1 - 7.8e-07 28.9 2.0 0.0014 18.2 0.2 2.7 1 1 1 2 2 2 2 PQQ-like domain eIF2A PF08662.11 KIK38353.1 - 2.1e-06 27.8 0.0 0.26 11.1 0.1 3.4 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK38353.1 - 6.3e-06 25.1 3.0 0.44 9.1 0.3 4.1 1 1 0 3 3 3 3 Nucleoporin Nup120/160 PD40 PF07676.12 KIK38353.1 - 1.6e-05 24.7 2.1 6.8 6.8 0.0 6.2 7 0 0 7 7 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KIK38353.1 - 1.7e-05 23.5 0.1 0.0024 16.4 0.1 2.3 1 1 1 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.5 KIK38353.1 - 0.00029 20.3 0.0 0.23 10.7 0.0 3.5 2 1 3 5 5 5 1 WD40-like domain DUF5046 PF16465.5 KIK38353.1 - 0.00069 19.1 0.1 0.011 15.3 0.1 2.4 1 1 0 2 2 2 1 Domain of unknown function (DUF5046) PQQ_3 PF13570.6 KIK38353.1 - 0.017 15.6 1.8 9.8 6.8 0.0 4.6 4 1 1 5 5 4 0 PQQ-like domain Frtz PF11768.8 KIK38353.1 - 0.018 13.4 0.0 8.8 4.5 0.0 3.0 2 1 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 KIK38353.1 - 0.039 13.3 0.8 6.6 6.0 0.0 3.5 1 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Formyl_trans_C PF02911.18 KIK38353.1 - 0.064 13.5 0.0 20 5.5 0.0 3.1 2 1 0 3 3 3 0 Formyl transferase, C-terminal domain DUF4875 PF16175.5 KIK38353.1 - 0.075 13.2 0.2 0.67 10.1 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4875) Str_synth PF03088.16 KIK38353.1 - 0.082 13.0 0.0 0.53 10.4 0.0 2.3 2 0 0 2 2 2 0 Strictosidine synthase DUF5570 PF17731.1 KIK38353.1 - 0.09 12.9 5.7 1.6 8.8 0.0 4.5 4 2 1 5 5 5 0 Family of unknown function (DUF5570) WD40 PF00400.32 KIK38355.1 - 1.1e-53 178.0 12.2 1.8e-07 31.7 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38355.1 - 2.5e-25 88.6 0.1 1.9e-05 24.8 0.1 5.9 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK38355.1 - 2.3e-13 49.8 0.3 0.077 11.9 0.0 6.2 1 1 6 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK38355.1 - 1.9e-08 34.0 0.3 7 6.7 0.0 7.5 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KIK38355.1 - 3.5e-08 33.6 0.0 0.07 13.0 0.0 3.5 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK38355.1 - 3.5e-08 32.6 0.2 0.33 9.5 0.0 4.3 2 1 1 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK38355.1 - 5.1e-07 29.3 0.0 0.002 17.5 0.0 3.8 3 1 1 4 4 4 2 WD40-like domain PQQ_2 PF13360.6 KIK38355.1 - 4.2e-06 26.5 0.6 0.011 15.3 0.2 3.2 1 1 1 2 2 2 2 PQQ-like domain Nbas_N PF15492.6 KIK38355.1 - 0.0002 20.8 1.3 0.53 9.6 0.0 4.2 1 1 3 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 KIK38355.1 - 0.0023 16.5 0.1 0.0049 15.5 0.1 1.6 2 0 0 2 2 2 1 Cytochrome D1 heme domain DUF5046 PF16465.5 KIK38355.1 - 0.0044 16.5 0.0 0.027 13.9 0.1 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF5046) PQQ PF01011.21 KIK38355.1 - 0.0052 16.7 0.0 31 4.7 0.0 4.9 5 0 0 5 5 5 0 PQQ enzyme repeat SGL PF08450.12 KIK38355.1 - 0.0084 15.7 0.6 3.6 7.1 0.0 3.1 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Frtz PF11768.8 KIK38355.1 - 0.011 14.0 0.0 3.3 5.9 0.0 3.3 2 2 1 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 KIK38355.1 - 0.029 14.8 0.9 4.1 8.0 0.0 4.2 4 1 1 5 5 5 0 PQQ-like domain IKI3 PF04762.12 KIK38355.1 - 0.033 12.2 0.3 0.61 8.0 0.1 2.6 1 1 1 3 3 3 0 IKI3 family WD40 PF00400.32 KIK38357.1 - 5.8e-49 163.0 15.1 7.5e-07 29.8 1.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38357.1 - 2.3e-22 79.1 1.0 0.00049 20.3 0.0 6.7 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK38357.1 - 1.3e-08 34.2 0.5 0.59 9.0 0.0 5.5 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK38357.1 - 4.3e-07 29.7 0.1 3.8 7.6 0.0 6.1 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KIK38357.1 - 1.5e-06 28.2 0.1 0.12 12.3 0.0 3.3 2 1 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK38357.1 - 4.5e-05 22.3 4.2 1.3 7.5 0.0 4.3 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK38357.1 - 0.00081 18.8 0.5 1.3 8.3 0.0 3.6 1 1 3 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.6 KIK38357.1 - 0.0014 18.3 2.2 0.27 10.8 2.2 2.6 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.16 KIK38357.1 - 0.0014 17.2 0.2 0.0028 16.3 0.2 1.5 1 0 0 1 1 1 1 Cytochrome D1 heme domain WD40_like PF17005.5 KIK38357.1 - 0.0023 17.3 0.1 0.5 9.6 0.1 3.3 4 0 0 4 4 4 1 WD40-like domain SGL PF08450.12 KIK38357.1 - 0.017 14.7 1.1 3.2 7.3 0.0 3.1 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region PQQ_3 PF13570.6 KIK38357.1 - 0.021 15.3 2.4 3.4 8.3 0.0 4.5 3 1 1 4 4 4 0 PQQ-like domain Frtz PF11768.8 KIK38357.1 - 0.025 12.9 0.0 1.1 7.5 0.0 2.7 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Sun2_CC2 PF18580.1 KIK38359.1 - 0.02 15.1 0.0 0.11 12.8 0.0 1.8 1 1 1 2 2 2 0 SUN2 coiled coil domain 2 Peptidase_S9 PF00326.21 KIK38361.1 - 3.5e-30 105.1 0.0 5.3e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KIK38361.1 - 1.8e-05 24.5 0.0 0.0057 16.3 0.1 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK38361.1 - 1.9e-05 24.1 0.1 0.0083 15.4 0.1 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S28 PF05577.12 KIK38361.1 - 0.095 11.5 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DUF2920 PF11144.8 KIK38361.1 - 0.099 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) FSH1 PF03959.13 KIK38361.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) TB2_DP1_HVA22 PF03134.19 KIK38366.1 - 1e-13 51.0 0.3 1.5e-13 50.4 0.2 1.4 1 1 0 1 1 1 1 TB2/DP1, HVA22 family G10 PF01125.17 KIK38367.1 - 1.1e-67 226.3 7.6 1.2e-67 226.2 7.6 1.0 1 0 0 1 1 1 1 G10 protein Zn_ribbon_recom PF13408.6 KIK38368.1 - 0.5 10.9 1.8 0.93 10.1 1.8 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain GDPD PF03009.17 KIK38370.1 - 1.6e-29 103.4 0.0 3.4e-29 102.4 0.0 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KIK38370.1 - 0.00041 20.7 0.9 0.0016 18.8 0.5 2.4 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Acyltransferase PF01553.21 KIK38371.1 - 1.3e-27 96.1 0.0 1.8e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF359 PF04019.12 KIK38371.1 - 0.047 13.3 0.2 0.78 9.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF359) CEBP_ZZ PF16366.5 KIK38372.1 - 0.036 14.3 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain EVE PF01878.18 KIK38373.1 - 9.2e-41 139.2 0.0 1.9e-40 138.3 0.0 1.5 1 0 0 1 1 1 1 EVE domain MmgE_PrpD PF03972.14 KIK38373.1 - 0.11 11.1 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 MmgE/PrpD family Band_7 PF01145.25 KIK38374.1 - 2.8e-23 82.9 5.5 4.4e-23 82.2 5.5 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family RRM_1 PF00076.22 KIK38375.1 - 6.4e-31 106.0 0.0 6.5e-16 57.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIK38375.1 - 1.1e-05 25.4 0.2 2.9e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 KIK38375.1 - 0.00077 19.4 0.0 0.0022 18.0 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KIK38375.1 - 0.0068 16.5 0.1 0.62 10.2 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 KIK38375.1 - 0.079 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RasGAP PF00616.19 KIK38377.1 - 4.2e-21 75.6 0.0 4.5e-14 52.6 0.0 2.8 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 KIK38377.1 - 1.9e-11 44.3 0.1 5.1e-11 42.9 0.1 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.6 KIK38377.1 - 0.0039 17.1 0.4 0.018 14.9 0.4 2.2 1 0 0 1 1 1 1 Cell morphogenesis C-terminal DUF257 PF03192.13 KIK38378.1 - 0.02 14.7 0.1 0.069 13.0 0.2 1.7 2 0 0 2 2 2 0 Pyrococcus protein of unknown function, DUF257 Gp-FAR-1 PF05823.12 KIK38378.1 - 0.11 12.8 1.7 0.25 11.7 1.7 1.5 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4709 PF15821.5 KIK38378.1 - 0.25 11.6 6.3 0.18 12.1 1.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4709) DUF4407 PF14362.6 KIK38378.1 - 4.1 6.7 9.4 0.72 9.1 5.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CorA PF01544.18 KIK38378.1 - 4.4 6.5 12.5 15 4.8 7.8 2.6 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein CtIP_N PF10482.9 KIK38378.1 - 7.4 6.7 13.7 0.41 10.7 6.3 2.6 2 1 1 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain TauD PF02668.16 KIK38381.1 - 2e-09 37.6 0.0 9.4e-07 28.9 0.0 2.1 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family DUF1751 PF08551.10 KIK38383.1 - 1.3 9.6 11.8 0.29 11.7 4.4 2.9 1 1 1 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) RNase_P_Rpp14 PF01900.19 KIK38385.1 - 1.1e-29 102.7 0.0 1.4e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Raffinose_syn PF05691.12 KIK38385.1 - 0.042 11.6 0.0 0.049 11.4 0.0 1.2 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Aminotran_1_2 PF00155.21 KIK38386.1 - 4.3e-30 105.1 0.0 2e-29 102.9 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KIK38386.1 - 0.0069 15.7 0.0 0.0098 15.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KIK38386.1 - 0.012 14.2 0.0 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 KIK38386.1 - 0.018 13.8 0.0 0.024 13.4 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain FAD_binding_3 PF01494.19 KIK38388.1 - 4.2e-15 55.8 1.1 1.2e-14 54.3 1.1 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK38388.1 - 6.7e-08 32.1 1.8 0.00016 21.0 0.3 2.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK38388.1 - 1.3e-07 31.1 0.3 4e-07 29.5 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KIK38388.1 - 4.3e-07 29.8 9.0 9.6e-05 22.1 2.4 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK38388.1 - 3e-06 27.3 2.7 8.2e-06 26.0 1.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIK38388.1 - 1.9e-05 23.6 2.4 0.00011 21.0 2.4 1.9 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KIK38388.1 - 4.8e-05 23.8 1.4 0.0057 17.2 0.6 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KIK38388.1 - 0.00019 20.8 0.3 0.57 9.4 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KIK38388.1 - 0.00041 19.7 0.6 0.00068 19.0 0.6 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIK38388.1 - 0.00051 19.2 0.3 0.00082 18.6 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KIK38388.1 - 0.0013 18.1 1.7 0.0018 17.7 0.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIK38388.1 - 0.0099 14.8 0.2 0.38 9.6 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase DUF4506 PF14958.6 KIK38388.1 - 0.011 15.2 0.1 0.039 13.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4506) Lycopene_cycl PF05834.12 KIK38388.1 - 0.045 12.8 2.9 1.1 8.3 0.4 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KIK38388.1 - 0.064 12.5 0.4 0.11 11.7 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Oest_recep PF02159.15 KIK38388.1 - 0.2 12.1 0.0 0.55 10.7 0.0 1.7 2 0 0 2 2 2 0 Oestrogen receptor MBOAT PF03062.19 KIK38389.1 - 4.1e-49 167.8 21.4 4.1e-49 167.8 21.4 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family CK_II_beta PF01214.18 KIK38390.1 - 1.2e-78 263.1 0.0 1.4e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF4139 PF13598.6 KIK38392.1 - 1.6e-21 77.0 0.5 2.5e-21 76.3 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) Nucleoporin_FG PF13634.6 KIK38392.1 - 0.0013 19.5 14.7 0.0013 19.5 14.7 2.5 1 1 1 2 2 2 1 Nucleoporin FG repeat region DUF4140 PF13600.6 KIK38392.1 - 0.016 15.7 0.5 0.19 12.2 0.0 2.9 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) RestrictionSfiI PF11487.8 KIK38392.1 - 0.034 14.0 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Type II restriction enzyme SfiI HAUS-augmin3 PF14932.6 KIK38392.1 - 0.099 12.2 0.2 3.1 7.3 0.0 2.8 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 NPCBM_assoc PF10633.9 KIK38392.1 - 0.24 11.7 6.5 6 7.2 0.1 3.9 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase ARD PF03079.14 KIK38393.1 - 1.3e-40 139.1 0.1 1.6e-40 138.9 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KIK38393.1 - 7.9e-10 38.3 0.0 1.7e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KIK38393.1 - 1.4e-07 31.5 0.1 2.2e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KIK38393.1 - 0.0004 20.0 0.0 0.00076 19.1 0.0 1.4 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.6 KIK38393.1 - 0.026 14.2 0.0 0.045 13.5 0.0 1.3 1 1 0 1 1 1 0 Cupin-like domain 3-HAO PF06052.12 KIK38393.1 - 0.049 13.3 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase Cupin_3 PF05899.12 KIK38393.1 - 0.077 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF1296 PF06972.11 KIK38393.1 - 0.12 12.6 0.2 0.19 11.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) FmdA_AmdA PF03069.15 KIK38394.1 - 3e-153 510.1 0.0 3.7e-153 509.8 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Sdh_cyt PF01127.22 KIK38395.1 - 3.5e-24 85.2 0.9 4.3e-24 84.9 0.9 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit MFS_1 PF07690.16 KIK38396.1 - 1.1e-39 136.4 52.2 9.9e-35 120.1 50.1 3.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK38396.1 - 0.00091 18.2 36.4 0.0036 16.2 15.5 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 KIK38396.1 - 0.092 11.0 19.3 0.021 13.2 0.5 3.6 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF3139 PF11337.8 KIK38396.1 - 1.3 9.7 4.9 49 4.7 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) Pur_DNA_glyco PF02245.16 KIK38397.1 - 0.0042 16.5 0.3 0.0086 15.5 0.1 1.6 2 0 0 2 2 2 1 Methylpurine-DNA glycosylase (MPG) DUF4071 PF13281.6 KIK38397.1 - 0.11 11.6 0.6 0.12 11.4 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) Prefoldin PF02996.17 KIK38401.1 - 7.5e-14 51.7 0.0 8.1e-14 51.6 0.0 1.0 1 0 0 1 1 1 1 Prefoldin subunit RicinB_lectin_2 PF14200.6 KIK38403.1 - 4.2e-11 43.4 3.4 1.7e-07 31.9 0.3 2.2 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like SANTA PF09133.10 KIK38403.1 - 0.04 14.4 0.0 0.073 13.6 0.0 1.4 1 0 0 1 1 1 0 SANTA (SANT Associated) Hva1_TUDOR PF11160.8 KIK38405.1 - 5e-16 58.6 3.8 5.8e-16 58.4 3.8 1.1 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain ProQ_C PF17516.2 KIK38405.1 - 0.028 13.8 0.2 0.11 11.9 0.1 2.0 1 1 1 2 2 2 0 ProQ C-terminal domain Glyco_hydro_28 PF00295.17 KIK38407.1 - 6.2e-59 199.7 14.8 7.8e-59 199.3 14.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DIM1 PF02966.16 KIK38408.1 - 1.7e-68 228.5 0.1 1.9e-68 228.3 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KIK38408.1 - 3e-05 23.9 0.1 4.1e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredox_DsbH PF03190.15 KIK38408.1 - 0.0015 18.5 0.4 0.0029 17.6 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_8 PF13905.6 KIK38408.1 - 0.013 15.8 0.5 0.02 15.2 0.5 1.3 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.6 KIK38408.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Herpes_pp85 PF04637.12 KIK38409.1 - 0.3 9.5 0.8 0.4 9.0 0.4 1.3 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Pyr_redox_2 PF07992.14 KIK38410.1 - 2.7e-25 89.2 0.0 6.9e-23 81.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK38410.1 - 4e-11 43.3 0.1 8.5e-10 39.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK38410.1 - 0.0037 16.6 0.0 0.18 11.0 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK38410.1 - 0.021 14.0 0.0 0.058 12.5 0.0 1.7 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) AMP-binding PF00501.28 KIK38411.1 - 1e-59 202.3 0.0 1.3e-59 201.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 KIK38411.1 - 3.3e-27 96.1 0.0 8.2e-27 94.8 0.0 1.7 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 KIK38411.1 - 9.7e-09 35.5 0.0 6.7e-08 32.8 0.0 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 KIK38411.1 - 1.3e-05 25.9 0.0 5.2e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family PE-PPE PF08237.11 KIK38411.1 - 0.04 13.5 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 PE-PPE domain MFS_1 PF07690.16 KIK38417.1 - 1.9e-28 99.4 28.9 1.9e-28 99.4 28.9 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK38417.1 - 2.8e-11 42.9 10.5 2.8e-11 42.9 10.5 2.5 2 1 0 3 3 3 1 Sugar (and other) transporter DUF697 PF05128.12 KIK38417.1 - 0.19 11.5 0.5 0.73 9.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF697) DUF2627 PF11118.8 KIK38417.1 - 9.5 6.9 10.5 5.7 7.6 0.4 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2627) MFS_1 PF07690.16 KIK38418.1 - 2.2e-32 112.4 27.9 2.2e-32 112.4 27.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK38418.1 - 5.1e-05 21.9 3.1 5.1e-05 21.9 3.1 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DEAD PF00270.29 KIK38419.1 - 2e-15 57.0 0.0 3.9e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK38419.1 - 1.2e-12 48.1 0.0 1.4e-11 44.7 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KIK38419.1 - 6.7e-09 36.3 1.7 1.7e-08 35.0 1.7 1.7 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KIK38419.1 - 0.00025 21.1 0.0 0.00054 20.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Phage_antitermQ PF06530.12 KIK38419.1 - 0.014 15.3 0.2 0.046 13.6 0.2 1.9 2 0 0 2 2 2 0 Phage antitermination protein Q DUF5082 PF16888.5 KIK38419.1 - 0.014 15.6 0.3 0.037 14.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) RQC PF09382.10 KIK38419.1 - 0.027 14.2 0.0 5.6 6.8 0.0 2.5 2 0 0 2 2 2 0 RQC domain WD40 PF00400.32 KIK38422.1 - 5e-08 33.5 8.0 0.1 13.5 0.1 6.0 7 0 0 7 7 7 2 WD domain, G-beta repeat SRA1 PF07304.11 KIK38422.1 - 8.7e-06 25.6 0.0 8.7e-06 25.6 0.0 2.8 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) DEAD PF00270.29 KIK38422.1 - 0.026 14.3 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase Sec16_C PF12931.7 KIK38422.1 - 0.059 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 F-box-like PF12937.7 KIK38423.1 - 0.00052 19.8 0.8 0.0038 17.1 0.1 2.8 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 KIK38423.1 - 0.095 13.2 0.6 17 6.0 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) L27_2 PF09045.10 KIK38423.1 - 0.16 12.0 0.4 0.35 10.8 0.4 1.5 1 0 0 1 1 1 0 L27_2 CPSF_A PF03178.15 KIK38424.1 - 3e-80 270.0 0.0 6.9e-80 268.8 0.0 1.6 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 KIK38424.1 - 2e-21 76.2 0.0 4.2e-21 75.1 0.0 1.6 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term ATP_bind_1 PF03029.17 KIK38425.1 - 4.7e-75 252.5 0.0 5.7e-75 252.2 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein IATP PF04568.12 KIK38425.1 - 0.042 14.3 0.4 0.086 13.3 0.4 1.5 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP zf-B_box PF00643.24 KIK38427.1 - 0.15 12.3 0.6 0.062 13.5 4.8 5.8 4 2 1 5 5 5 0 B-box zinc finger DUF3331 PF11811.8 KIK38428.1 - 0.15 12.0 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3331) PilJ PF13675.6 KIK38428.1 - 0.16 12.0 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term GST_N_3 PF13417.6 KIK38429.1 - 1.6e-11 44.4 0.0 3.3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK38429.1 - 5e-08 33.1 0.0 1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK38429.1 - 3.6e-07 30.1 0.0 7.1e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KIK38429.1 - 8.8e-06 26.0 0.0 2.5e-05 24.5 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK38429.1 - 5.1e-05 23.4 0.1 0.00019 21.6 0.1 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK38429.1 - 0.0039 17.3 0.0 0.0097 16.1 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KIK38429.1 - 0.006 16.8 0.0 0.0096 16.1 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin p450 PF00067.22 KIK38430.1 - 1.7e-41 142.4 0.0 2e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-MYND PF01753.18 KIK38432.1 - 4.7e-07 29.8 12.2 8.9e-07 28.9 12.2 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIK38432.1 - 0.007 16.7 10.0 0.015 15.6 10.0 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding RPAP3_C PF13877.6 KIK38432.1 - 0.086 13.4 0.2 0.21 12.1 0.2 1.6 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 APG17 PF04108.12 KIK38432.1 - 0.12 11.5 0.1 1.1 8.3 0.1 2.0 2 0 0 2 2 2 0 Autophagy protein Apg17 BCS1_N PF08740.11 KIK38433.1 - 4.8e-38 131.0 0.8 7.5e-38 130.4 0.8 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KIK38433.1 - 1.2e-14 54.9 0.0 7.8e-14 52.2 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK38433.1 - 0.00053 20.4 0.0 0.0019 18.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KIK38433.1 - 0.00068 18.9 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KIK38433.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 KIK38433.1 - 0.063 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 KIK38433.1 - 0.064 13.2 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 KIK38433.1 - 0.066 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KIK38433.1 - 0.068 13.2 0.0 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIK38433.1 - 0.12 12.6 0.0 0.39 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KIK38433.1 - 0.13 12.8 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 KIK38433.1 - 0.13 11.5 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin PAP2 PF01569.21 KIK38434.1 - 1.1e-13 51.1 7.2 7.1e-13 48.5 7.2 2.1 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 KIK38434.1 - 0.021 14.9 1.6 0.51 10.5 0.2 2.7 2 1 0 2 2 2 0 Divergent PAP2 family Acetyltransf_3 PF13302.7 KIK38435.1 - 1e-15 58.7 0.0 1.8e-15 57.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIK38435.1 - 0.027 14.2 0.3 0.34 10.6 0.1 2.3 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK38435.1 - 0.15 12.3 0.1 0.24 11.6 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family AA_permease PF00324.21 KIK38438.1 - 5.5e-07 28.5 1.2 5.8e-07 28.5 1.2 1.0 1 0 0 1 1 1 1 Amino acid permease Pantoate_ligase PF02569.15 KIK38440.1 - 7.9e-92 307.2 0.0 9e-92 307.0 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Ribonuc_P_40 PF08584.11 KIK38441.1 - 2.3e-25 89.4 0.0 1.3e-24 87.0 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit MFS_1 PF07690.16 KIK38443.1 - 5.6e-31 107.7 34.4 7.8e-31 107.3 34.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily VPS9 PF02204.18 KIK38445.1 - 1.7e-30 105.3 0.0 2.9e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KIK38445.1 - 1.5e-17 63.7 1.2 4.2e-17 62.2 1.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 KIK38445.1 - 0.0041 16.8 0.0 0.013 15.2 0.0 1.8 2 0 0 2 2 2 1 CUE domain DUF1752 PF08550.10 KIK38449.1 - 1.6e-06 27.9 10.4 3.4e-06 26.8 10.4 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) FAM220 PF15487.6 KIK38449.1 - 0.0047 16.6 2.8 0.0074 16.0 2.8 1.3 1 0 0 1 1 1 1 FAM220 family SAP PF02037.27 KIK38450.1 - 0.00026 20.6 5.6 0.022 14.5 0.0 3.9 4 0 0 4 4 4 2 SAP domain NYD-SP28 PF14772.6 KIK38450.1 - 0.00056 19.9 0.4 0.0015 18.5 0.4 1.7 1 0 0 1 1 1 1 Sperm tail Packaging_FI PF14000.6 KIK38450.1 - 0.14 12.6 0.0 3.7 8.0 0.0 2.4 2 0 0 2 2 2 0 DNA packaging protein FI WD40 PF00400.32 KIK38451.1 - 1.5e-08 35.2 2.5 0.00075 20.3 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38451.1 - 7.2e-06 26.2 0.0 0.0016 18.7 0.0 3.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PalH PF08733.10 KIK38453.1 - 0.16 11.0 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 PalH/RIM21 BioT2 PF15368.6 KIK38454.1 - 0.22 11.5 1.2 5.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Spermatogenesis family BioT2 AAA_13 PF13166.6 KIK38454.1 - 1.3 7.6 4.1 1.8 7.1 4.1 1.1 1 0 0 1 1 1 0 AAA domain DNase-RNase PF02577.14 KIK38455.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Bifunctional nuclease Peptidase_S49_N PF08496.10 KIK38458.1 - 1.2 9.2 2.9 2.6 8.1 2.8 1.5 1 1 0 1 1 1 0 Peptidase family S49 N-terminal UQ_con PF00179.26 KIK38459.1 - 1.3e-11 44.3 0.0 1.8e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Mig-14 PF07395.11 KIK38459.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.1 1 0 0 1 1 1 0 Mig-14 WD40 PF00400.32 KIK38461.1 - 1.4e-11 44.7 2.2 1.4e-07 32.1 0.3 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38461.1 - 6.9e-09 35.9 0.0 2e-05 24.8 0.0 3.5 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain MFS_1 PF07690.16 KIK38462.1 - 1.1e-10 41.0 6.3 1.3e-10 40.8 6.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK38462.1 - 0.002 17.1 5.4 0.002 17.1 5.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter C_GCAxxG_C_C PF09719.10 KIK38462.1 - 0.14 12.4 1.7 0.19 12.0 1.7 1.2 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) WD40 PF00400.32 KIK38463.1 - 6.5e-17 61.6 6.6 9.2e-08 32.6 1.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38463.1 - 3.5e-06 27.2 0.1 0.045 14.1 0.1 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK38463.1 - 0.00018 21.4 1.0 0.59 10.1 0.0 3.1 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK38463.1 - 0.00026 20.0 0.1 0.53 9.2 0.0 2.1 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TMEM210 PF15195.6 KIK38465.1 - 0.16 12.4 0.1 0.26 11.7 0.1 1.3 1 0 0 1 1 1 0 TMEM210 family DUF485 PF04341.12 KIK38466.1 - 0.41 10.6 5.5 0.16 11.9 0.6 2.5 3 0 0 3 3 3 0 Protein of unknown function, DUF485 LRR19-TM PF15176.6 KIK38467.1 - 0.12 12.4 2.3 0.42 10.6 0.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF4407 PF14362.6 KIK38467.1 - 0.44 9.8 2.7 5.6 6.2 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CMAS PF02353.20 KIK38468.1 - 5.2e-68 229.3 0.0 6.4e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KIK38468.1 - 3.8e-13 49.9 0.0 2e-12 47.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK38468.1 - 2e-12 47.6 0.0 5.9e-12 46.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK38468.1 - 2.2e-11 43.9 0.0 4.4e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK38468.1 - 1.9e-05 25.3 0.0 4.2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK38468.1 - 0.00019 21.3 0.0 0.00037 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KIK38468.1 - 0.00036 20.1 0.0 0.00066 19.3 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 KIK38468.1 - 0.00047 19.7 0.0 0.00079 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KIK38468.1 - 0.014 14.8 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KIK38468.1 - 0.019 14.7 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KIK38468.1 - 0.065 13.2 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 KIK38468.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain YIF1 PF03878.15 KIK38471.1 - 3.6e-89 298.4 0.6 4.2e-89 298.2 0.6 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KIK38471.1 - 4.9e-05 23.1 4.0 7.7e-05 22.5 4.0 1.2 1 0 0 1 1 1 1 Yip1 domain Transmemb_17 PF09799.9 KIK38474.1 - 0.035 14.7 4.2 0.035 14.7 4.2 2.7 3 0 0 3 3 3 0 Predicted membrane protein Pox_F16 PF04708.12 KIK38474.1 - 0.067 12.6 0.1 0.095 12.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus F16 protein Ni_hydr_CYTB PF01292.20 KIK38474.1 - 0.13 11.8 6.7 0.019 14.5 2.3 2.1 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF2973 PF11189.8 KIK38474.1 - 0.23 11.6 0.0 0.23 11.6 0.0 2.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2973) SLATT_3 PF18184.1 KIK38474.1 - 5.9 7.0 5.5 1.8 8.7 0.6 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 DUF1097 PF06496.11 KIK38474.1 - 7.4 6.7 16.2 0.054 13.6 5.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1097) Nrap_D4 PF17405.2 KIK38475.1 - 1.3e-56 191.3 0.5 3.1e-56 190.1 0.0 1.9 2 0 0 2 2 2 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 KIK38475.1 - 1.1e-41 142.5 0.0 2.2e-41 141.6 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D2 PF17403.2 KIK38475.1 - 1.1e-37 129.1 0.0 7.1e-37 126.5 0.0 2.3 2 1 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D5 PF17406.2 KIK38475.1 - 9.9e-31 106.7 0.8 1.3e-24 86.8 0.1 3.4 3 1 1 4 4 4 2 Nrap protein PAP/OAS1-like domain 5 Nrap_D6 PF17407.2 KIK38475.1 - 1.6e-30 106.1 0.0 3.3e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 6 Nrap PF03813.14 KIK38475.1 - 1.1e-29 103.5 0.0 1.9e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 UBX PF00789.20 KIK38476.1 - 7.5e-08 32.5 0.0 1.4e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KIK38476.1 - 0.00011 21.9 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain CUE PF02845.16 KIK38476.1 - 0.19 11.5 0.3 0.5 10.1 0.1 1.8 2 0 0 2 2 2 0 CUE domain EF-hand_7 PF13499.6 KIK38477.1 - 6.3e-12 45.8 0.0 2.1e-06 28.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KIK38477.1 - 9.9e-12 43.8 0.2 0.00012 21.7 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KIK38477.1 - 1.7e-10 39.7 0.0 0.00032 20.0 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 KIK38477.1 - 3e-07 30.7 0.0 0.0013 19.0 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KIK38477.1 - 8.8e-05 22.3 0.1 0.002 17.9 0.0 2.7 2 2 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KIK38477.1 - 0.12 11.9 1.5 0.66 9.6 0.2 2.5 2 1 0 2 2 2 0 EF hand UPF0154 PF03672.13 KIK38477.1 - 0.14 12.2 0.0 5.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) ExbD PF02472.16 KIK38477.1 - 0.14 12.3 0.0 3.8 7.7 0.0 2.0 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR DDE_Tnp_IS66_C PF13817.6 KIK38477.1 - 0.21 11.9 0.1 0.6 10.4 0.1 1.7 2 0 0 2 2 2 0 IS66 C-terminal element SapB_1 PF05184.15 KIK38477.1 - 0.21 11.6 0.1 5.2 7.2 0.0 2.1 2 0 0 2 2 2 0 Saposin-like type B, region 1 ParA PF10609.9 KIK38480.1 - 1.1e-74 251.0 0.1 1.4e-74 250.6 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KIK38480.1 - 4.9e-12 46.0 0.0 7e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KIK38480.1 - 6.7e-10 39.2 0.2 1.3e-06 28.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain ArsA_ATPase PF02374.15 KIK38480.1 - 2.5e-06 26.9 0.1 0.0011 18.2 0.1 2.3 2 0 0 2 2 2 2 Anion-transporting ATPase MipZ PF09140.11 KIK38480.1 - 4.3e-06 26.2 0.1 8.3e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.6 KIK38480.1 - 0.0031 17.1 0.0 0.0087 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KIK38480.1 - 0.056 12.6 0.1 0.08 12.1 0.1 1.1 1 0 0 1 1 1 0 NB-ARC domain Fer4_NifH PF00142.18 KIK38480.1 - 0.072 12.5 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 KIK38480.1 - 0.17 11.7 0.2 2 8.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KIK38480.1 - 0.18 11.3 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein CLP1_P PF16575.5 KIK38480.1 - 0.22 11.3 0.0 0.37 10.6 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF4690 PF15756.5 KIK38481.1 - 0.29 11.8 2.6 0.56 10.8 0.0 2.4 2 0 0 2 2 2 0 Small Novel Rich in Cartilage PEPCK_ATP PF01293.20 KIK38482.1 - 1.3e-218 726.4 0.0 1.5e-218 726.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 KIK38482.1 - 0.046 13.9 0.0 0.081 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK38482.1 - 0.11 12.2 0.1 0.31 10.8 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KIK38482.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter UQ_con PF00179.26 KIK38483.1 - 1.1e-42 145.0 0.0 1.4e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KIK38483.1 - 0.00057 19.7 0.1 0.001 18.9 0.1 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 KIK38483.1 - 0.019 15.3 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 KIK38483.1 - 0.031 14.0 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B MSP1_C PF07462.11 KIK38483.1 - 0.11 11.2 1.3 0.14 10.8 1.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Plk4_PB1 PF18190.1 KIK38483.1 - 0.12 12.5 0.1 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 1 Mucin PF01456.17 KIK38483.1 - 0.3 11.1 10.9 0.44 10.5 10.9 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Pkinase_Tyr PF07714.17 KIK38484.1 - 4.5e-21 75.3 0.0 5.7e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK38484.1 - 4.4e-20 72.1 0.0 5.7e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK38484.1 - 0.0093 15.9 0.2 0.018 14.9 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK38484.1 - 0.054 12.4 0.0 0.076 11.9 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KIK38484.1 - 0.12 11.9 0.2 0.17 11.4 0.2 1.2 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 KIK38484.1 - 0.23 10.5 0.2 0.31 10.1 0.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF2828 PF11443.8 KIK38485.1 - 2e-208 693.6 0.0 3.2e-208 692.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) DUF1654 PF07867.11 KIK38485.1 - 0.94 9.3 3.1 12 5.7 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1654) F-box-like PF12937.7 KIK38487.1 - 3.4e-10 39.7 0.1 9.4e-10 38.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK38487.1 - 0.0015 18.4 0.0 0.0085 15.9 0.0 2.2 1 1 1 2 2 2 1 F-box domain Coatomer_WDAD PF04053.14 KIK38488.1 - 1.5e-150 502.2 0.0 3.8e-150 500.8 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KIK38488.1 - 2.2e-36 123.2 7.7 4.9e-06 27.2 0.0 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38488.1 - 2.8e-08 34.0 0.2 0.013 15.7 0.0 6.1 4 1 1 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK38488.1 - 0.00026 19.8 0.5 1.5 7.3 0.0 3.4 1 1 1 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KIK38488.1 - 0.0016 18.4 0.1 14 5.8 0.0 4.7 2 1 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Binary_toxB_2 PF17475.2 KIK38488.1 - 0.0019 18.0 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 Clostridial binary toxin B/anthrax toxin PA domain 2 MetallophosC PF16370.5 KIK38488.1 - 0.02 15.1 0.1 0.13 12.5 0.1 2.4 1 1 1 2 2 2 0 C terminal of Calcineurin-like phosphoesterase Chitin_synth_2 PF03142.15 KIK38489.1 - 1.6e-214 713.4 3.7 1.1e-212 707.4 3.7 2.2 1 1 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KIK38489.1 - 1.7e-104 350.4 0.0 1.6e-103 347.2 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 KIK38489.1 - 5.4e-17 61.7 0.4 1.3e-10 41.3 0.0 3.4 3 1 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 KIK38489.1 - 2.1e-14 53.1 0.2 4.5e-14 52.1 0.2 1.6 1 0 0 1 1 1 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 KIK38489.1 - 5.2e-10 39.6 0.0 7e-09 35.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIK38489.1 - 4.7e-08 33.0 0.0 8.7e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 KIK38489.1 - 9.1e-07 29.0 1.6 3.1e-06 27.2 1.6 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KIK38489.1 - 0.0086 15.6 0.0 0.024 14.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 21 NUDIX PF00293.28 KIK38491.1 - 3.1e-11 43.4 0.0 6.1e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain His_Phos_2 PF00328.22 KIK38492.1 - 3.5e-53 181.3 0.0 4.2e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) WD40 PF00400.32 KIK38494.1 - 7.3e-30 102.6 5.2 6.1e-08 33.2 0.6 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38494.1 - 4.4e-09 36.5 0.1 0.029 14.7 0.0 4.2 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK38494.1 - 1.9e-05 23.6 0.3 0.15 10.6 0.1 2.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.12 KIK38494.1 - 0.011 15.7 0.0 12 6.0 0.0 3.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK38494.1 - 0.2 11.0 0.0 22 4.2 0.0 2.8 3 0 0 3 3 3 0 WD40-like domain Putative_PNPOx PF01243.20 KIK38495.1 - 1.2e-06 28.6 0.0 2.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase WD40 PF00400.32 KIK38496.1 - 1.1e-28 98.8 14.9 4.3e-07 30.5 0.5 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38496.1 - 0.00034 20.8 0.9 1.6 9.1 0.0 4.2 1 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK38496.1 - 0.0018 18.1 0.2 17 5.5 0.0 3.8 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK38496.1 - 0.0072 15.0 0.7 0.14 10.8 0.1 2.7 3 0 0 3 3 3 1 Nucleoporin Nup120/160 DPPIV_N PF00930.21 KIK38496.1 - 0.063 12.0 0.5 0.77 8.4 0.1 2.7 2 2 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region UDPG_MGDP_dh_N PF03721.14 KIK38499.1 - 4.6e-58 195.9 0.0 8.4e-58 195.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KIK38499.1 - 6.4e-34 116.5 0.0 3.8e-33 114.0 0.1 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KIK38499.1 - 6.6e-31 106.4 0.1 1.3e-30 105.5 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Sacchrp_dh_NADP PF03435.18 KIK38499.1 - 0.12 12.6 0.1 0.46 10.8 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TPPK_C PF12555.8 KIK38501.1 - 0.16 12.1 0.2 0.31 11.1 0.2 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Epimerase PF01370.21 KIK38503.1 - 2.4e-51 174.5 0.0 3.8e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK38503.1 - 1.2e-14 54.4 0.0 1.2e-13 51.1 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIK38503.1 - 0.00051 19.3 2.5 0.032 13.4 1.4 3.2 2 2 1 3 3 3 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KIK38503.1 - 0.0015 17.7 0.0 0.003 16.7 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KIK38503.1 - 0.15 11.0 0.1 0.68 8.9 0.1 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PAPS_reduct PF01507.19 KIK38504.1 - 3.4e-23 82.6 0.0 1.1e-22 80.9 0.0 1.8 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Mistic PF11458.8 KIK38504.1 - 0.0096 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Membrane-integrating protein Mistic SPOB_ab PF14682.6 KIK38504.1 - 0.012 15.7 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Prok-E2_C PF14459.6 KIK38504.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family C BTB PF00651.31 KIK38505.1 - 2e-09 37.6 0.0 3.8e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF775 PF05603.12 KIK38507.1 - 1.9e-51 174.5 0.0 2.1e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) FxsA PF04186.13 KIK38507.1 - 0.054 13.6 0.4 1.8 8.7 0.2 2.6 1 1 1 2 2 2 0 FxsA cytoplasmic membrane protein Ig_Tie2_1 PF10430.9 KIK38508.1 - 0.0056 17.1 0.0 0.0063 16.9 0.0 1.2 1 0 0 1 1 1 1 Tie-2 Ig-like domain 1 Fungal_trans PF04082.18 KIK38510.1 - 4.5e-33 114.4 0.0 1.3e-32 112.9 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK38510.1 - 4.8e-07 29.8 9.6 7.7e-07 29.1 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UCH PF00443.29 KIK38511.1 - 1.4e-08 34.5 0.0 1.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 KIK38511.1 - 0.0042 16.9 0.1 0.15 11.9 0.0 2.6 2 0 0 2 2 2 1 UBA-like domain UIM PF02809.20 KIK38511.1 - 0.38 10.8 1.6 10 6.3 0.1 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif Copper-fist PF00649.18 KIK38512.1 - 5e-21 73.9 1.9 5e-21 73.9 1.9 2.4 1 1 1 2 2 2 1 Copper fist DNA binding domain DnaJ PF00226.31 KIK38513.1 - 1.4e-17 63.6 0.3 3.9e-17 62.1 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain DUF2714 PF10896.8 KIK38513.1 - 0.0058 16.7 0.2 0.018 15.1 0.1 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2714) Borrelia_P83 PF05262.11 KIK38513.1 - 1.7 7.1 25.3 3.2 6.2 25.3 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_23 PF13476.6 KIK38513.1 - 1.8 9.0 19.2 0.26 11.8 13.6 2.0 2 0 0 2 2 2 0 AAA domain DUF5427 PF10310.9 KIK38513.1 - 9.6 5.0 24.7 16 4.3 24.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Pkinase PF00069.25 KIK38514.1 - 2.7e-48 164.7 0.0 3.4e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK38514.1 - 1.6e-22 80.0 0.0 2.1e-16 60.0 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIK38514.1 - 1.2e-05 24.8 0.6 0.023 14.0 0.2 2.9 2 1 0 2 2 2 2 Kinase-like APH PF01636.23 KIK38514.1 - 0.00031 20.7 0.7 0.0022 18.0 0.7 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK38514.1 - 0.0041 16.0 0.0 0.009 14.8 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 KIK38514.1 - 0.0057 15.7 0.0 0.0092 15.0 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 KIK38514.1 - 0.027 13.4 0.0 0.062 12.2 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 KIK38514.1 - 0.11 11.8 0.4 0.14 11.5 0.4 1.3 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIK38514.1 - 0.25 10.9 0.1 0.7 9.5 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Plavaka PF18759.1 KIK38518.1 - 3.9e-90 302.4 0.0 9.5e-90 301.1 0.0 1.6 2 0 0 2 2 2 1 Plavaka transposase SUZ-C PF12901.7 KIK38518.1 - 0.16 12.0 0.6 0.36 10.9 0.6 1.5 1 0 0 1 1 1 0 SUZ-C motif RhoGAP PF00620.27 KIK38519.1 - 8.1e-07 29.0 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 KIK38519.1 - 6.3e-06 25.9 0.0 1.6e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family INPP5B_PH PF16776.5 KIK38519.1 - 0.002 17.9 0.1 0.0062 16.3 0.1 1.8 2 0 0 2 2 2 1 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain HABP4_PAI-RBP1 PF04774.15 KIK38520.1 - 7.2e-05 23.6 7.6 0.0001 23.2 7.6 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family DUF4962 PF16332.5 KIK38520.1 - 0.08 11.4 0.8 0.094 11.2 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) BTB PF00651.31 KIK38521.1 - 1.3e-11 44.7 0.0 2.1e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Glyco_transf_22 PF03901.17 KIK38522.1 - 6.6e-61 206.8 21.5 8.3e-61 206.5 21.5 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family TFIIS_C PF01096.18 KIK38523.1 - 9e-12 44.7 2.7 9e-12 44.7 2.7 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KIK38523.1 - 2.1e-09 37.1 1.0 2.1e-09 37.1 1.0 3.3 4 0 0 4 4 4 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.6 KIK38523.1 - 0.0028 18.0 0.3 0.0028 18.0 0.3 2.1 2 1 0 2 2 2 1 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.10 KIK38523.1 - 0.0065 16.6 6.9 0.92 9.7 0.2 3.7 4 0 0 4 4 4 2 Zinc ribbon domain zf_UBZ PF18439.1 KIK38523.1 - 0.03 13.9 10.3 0.92 9.2 0.1 3.7 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Zn_Tnp_IS1595 PF12760.7 KIK38523.1 - 0.035 14.1 2.5 0.035 14.1 2.5 2.8 2 2 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.7 KIK38523.1 - 0.042 13.9 10.1 1.1 9.4 1.1 2.7 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 KIK38523.1 - 0.063 13.5 6.9 0.43 10.9 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon C1_1 PF00130.22 KIK38523.1 - 0.065 13.1 0.4 0.065 13.1 0.4 2.7 2 2 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ribbon_3 PF13248.6 KIK38523.1 - 0.076 12.4 0.3 0.076 12.4 0.3 3.6 5 0 0 5 5 4 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KIK38523.1 - 0.079 12.7 7.4 2.6 7.9 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.13 KIK38523.1 - 0.085 12.6 0.4 0.085 12.6 0.4 2.8 4 0 0 4 4 3 0 InsA N-terminal domain DUF3268 PF11672.8 KIK38523.1 - 0.094 13.1 0.4 0.094 13.1 0.4 2.2 2 1 0 2 2 2 0 zinc-finger-containing domain zf-ISL3 PF14690.6 KIK38523.1 - 0.13 13.0 0.6 0.13 13.0 0.6 2.7 2 2 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2H2 PF00096.26 KIK38523.1 - 0.19 12.2 0.8 0.19 12.2 0.8 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type zinc_ribbon_4 PF13717.6 KIK38523.1 - 0.2 11.6 8.7 2.9 7.9 0.3 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Zn_ribbon_recom PF13408.6 KIK38523.1 - 0.22 12.1 6.9 2.4 8.7 0.6 2.6 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-ACC PF17848.1 KIK38523.1 - 0.33 11.1 11.4 14 5.9 0.1 4.0 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain Elf1 PF05129.13 KIK38523.1 - 0.58 10.2 9.3 1.1 9.4 2.8 2.7 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like eIF-5_eIF-2B PF01873.17 KIK38523.1 - 0.82 9.6 5.8 1.5 8.7 0.8 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-AN1 PF01428.16 KIK38523.1 - 1.1 9.4 10.4 5.8 7.2 0.3 3.6 3 1 0 3 3 3 0 AN1-like Zinc finger DpnI PF06044.12 KIK38523.1 - 1.2 8.7 6.2 1.3 8.7 0.3 2.1 2 0 0 2 2 2 0 Dam-replacing family UPF0547 PF10571.9 KIK38523.1 - 1.5 9.0 0.1 1.5 9.0 0.1 3.8 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-LITAF-like PF10601.9 KIK38523.1 - 3.7 7.9 11.6 12 6.3 2.6 3.3 3 1 0 3 3 3 0 LITAF-like zinc ribbon domain CpXC PF14353.6 KIK38523.1 - 4.1 7.5 9.4 0.41 10.7 1.7 2.7 2 1 0 3 3 3 0 CpXC protein RecR PF02132.15 KIK38523.1 - 5 6.8 12.6 0.11 12.1 2.5 3.1 3 1 0 3 3 3 0 RecR protein zinc_ribbon_10 PF10058.9 KIK38523.1 - 5.2 6.9 10.9 1.5 8.6 2.3 3.1 2 2 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF2197 PF09963.9 KIK38523.1 - 6.1 7.2 9.9 3.2 8.1 0.3 3.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) Nudix_N_2 PF14803.6 KIK38523.1 - 6.3 6.8 10.2 33 4.5 0.2 3.5 3 1 0 3 3 3 0 Nudix N-terminal ADK_lid PF05191.14 KIK38523.1 - 7.1 6.7 8.0 9.2 6.3 0.1 3.5 4 0 0 4 4 4 0 Adenylate kinase, active site lid Hydrophobin PF01185.18 KIK38525.1 - 6.2e-22 78.0 12.4 8.2e-22 77.6 12.4 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_12 PF07740.12 KIK38525.1 - 2.3 9.0 10.5 4.3 8.1 2.1 2.5 2 0 0 2 2 2 0 Ion channel inhibitory toxin DUF4282 PF14110.6 KIK38529.1 - 0.84 10.4 4.9 1.5 9.6 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) Ribosomal_L27e PF01777.18 KIK38530.1 - 1.6e-36 124.5 4.1 2.3e-36 124.0 4.1 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KIK38530.1 - 0.0052 16.7 0.4 0.012 15.6 0.4 1.7 1 0 0 1 1 1 1 KOW motif Nucleoporin_FG PF13634.6 KIK38531.1 - 8.7e-37 125.9 166.6 1.2e-10 42.1 14.7 6.1 2 1 4 6 6 6 5 Nucleoporin FG repeat region Nup54 PF13874.6 KIK38531.1 - 1.9e-34 118.7 4.7 4.7e-34 117.5 4.7 1.6 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Nup54_C PF18437.1 KIK38531.1 - 0.0021 17.9 0.2 0.0021 17.9 0.2 2.5 3 0 0 3 3 3 1 Nup54 C-terminal interacting domain WD40 PF00400.32 KIK38532.1 - 8.4e-23 80.2 1.7 5.4e-05 23.9 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38532.1 - 1.3e-09 38.3 0.0 0.013 15.8 0.0 4.9 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK38532.1 - 0.00042 20.3 0.0 0.34 10.8 0.0 3.3 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KIK38532.1 - 0.0071 15.4 0.0 3 6.8 0.0 3.0 2 1 0 2 2 2 2 Coatomer WD associated region PD40 PF07676.12 KIK38532.1 - 0.014 15.3 0.3 2.5 8.1 0.1 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK38532.1 - 0.044 12.7 0.0 7 5.5 0.0 2.8 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF-5_eIF-2B PF01873.17 KIK38533.1 - 2.8e-40 136.8 0.1 8.1e-40 135.4 0.0 1.7 2 0 0 2 2 2 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KIK38533.1 - 0.001 18.5 0.2 0.0023 17.4 0.2 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding AAA_23 PF13476.6 KIK38533.1 - 0.039 14.5 1.0 0.054 14.0 1.0 1.2 1 0 0 1 1 1 0 AAA domain zf-HYPF PF07503.12 KIK38533.1 - 0.089 12.6 0.1 19 5.1 0.0 2.5 2 0 0 2 2 2 0 HypF finger Arc_trans_TRASH PF08394.10 KIK38533.1 - 2 8.8 4.8 15 6.0 0.0 2.5 1 1 1 2 2 2 0 Archaeal TRASH domain ATP-synt PF00231.19 KIK38534.1 - 2.2e-82 276.9 5.1 2.5e-82 276.7 5.1 1.0 1 0 0 1 1 1 1 ATP synthase Ilar_coat PF01787.16 KIK38534.1 - 0.13 12.0 0.1 0.46 10.2 0.0 1.8 1 1 0 1 1 1 0 Ilarvirus coat protein FAD-oxidase_C PF02913.19 KIK38535.1 - 1.5e-55 188.6 0.0 2.9e-55 187.6 0.0 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KIK38535.1 - 2.2e-29 102.0 0.0 4.3e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Sun2_CC2 PF18580.1 KIK38535.1 - 0.17 12.2 0.5 4.3 7.6 0.0 3.1 3 0 0 3 3 3 0 SUN2 coiled coil domain 2 ApoLp-III PF07464.11 KIK38535.1 - 0.24 11.5 0.1 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF3267 PF11667.8 KIK38536.1 - 0.28 11.5 0.1 0.28 11.5 0.1 2.5 2 1 1 3 3 3 0 Putative zincin peptidase SAM_LFY PF01698.16 KIK38538.1 - 0.017 15.0 0.0 0.038 13.9 0.0 1.5 2 0 0 2 2 2 0 Floricaula / Leafy protein SAM domain DUF3069 PF11269.8 KIK38539.1 - 0.044 14.0 0.4 0.084 13.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3069) AMP_N PF05195.16 KIK38539.1 - 0.1 12.4 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain Integrase_H2C2 PF17921.1 KIK38540.1 - 2e-05 24.6 1.7 2e-05 24.6 1.7 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain HTH_Tnp_1_2 PF13022.6 KIK38541.1 - 0.058 13.6 0.6 0.1 12.8 0.6 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase Helitron_like_N PF14214.6 KIK38544.1 - 7.3e-12 45.9 0.2 8e-12 45.8 0.2 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus OHCU_decarbox PF09349.10 KIK38546.1 - 0.017 15.6 0.0 0.025 15.1 0.0 1.2 1 0 0 1 1 1 0 OHCU decarboxylase PAM2 PF07145.15 KIK38546.1 - 0.13 12.0 2.4 11 5.9 0.0 2.7 3 0 0 3 3 3 0 Ataxin-2 C-terminal region CobA_CobO_BtuR PF02572.15 KIK38547.1 - 0.098 12.9 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Nse4_C PF08743.10 KIK38549.1 - 1.6e-14 53.9 0.0 2.8e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Nse4 C-terminal NuA4 PF09340.10 KIK38550.1 - 0.16 11.9 0.2 0.35 10.8 0.2 1.5 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 AAA_12 PF13087.6 KIK38552.1 - 1.3e-59 201.2 0.0 1.9e-59 200.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK38552.1 - 9.9e-07 28.8 0.7 1.6e-06 28.1 0.7 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KIK38552.1 - 0.00021 21.1 0.0 0.048 13.4 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Ribosomal_S13_N PF08069.12 KIK38552.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain PIF1 PF05970.14 KIK38552.1 - 0.65 9.1 1.6 0.49 9.5 0.1 1.5 2 0 0 2 2 2 0 PIF1-like helicase UPF1_Zn_bind PF09416.10 KIK38553.1 - 1.2e-69 233.1 2.8 1.2e-69 233.1 2.8 2.1 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.6 KIK38553.1 - 5.4e-36 124.7 2.1 5.5e-21 75.5 0.7 2.2 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KIK38553.1 - 9.8e-36 121.9 0.0 1.8e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KIK38553.1 - 8.6e-12 45.2 0.1 1.9e-11 44.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK38553.1 - 5.3e-10 39.8 0.1 1.2e-09 38.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KIK38553.1 - 6.8e-06 26.2 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KIK38553.1 - 0.00011 22.1 0.1 0.00026 20.9 0.1 1.7 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 KIK38553.1 - 0.00031 20.4 0.1 0.00079 19.0 0.1 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 KIK38553.1 - 0.00072 18.9 0.1 0.0016 17.7 0.1 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KIK38553.1 - 0.0062 16.8 0.1 0.016 15.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 KIK38553.1 - 0.009 15.7 0.1 0.017 14.8 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_10 PF12846.7 KIK38553.1 - 0.012 14.6 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain DEAD PF00270.29 KIK38553.1 - 0.017 14.9 0.7 0.035 13.9 0.6 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase ATPase PF06745.13 KIK38553.1 - 0.036 13.4 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 KIK38553.1 - 0.045 13.2 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.29 KIK38553.1 - 0.059 13.8 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KIK38553.1 - 0.065 13.1 0.0 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 KIK38553.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain UDPGT PF00201.18 KIK38553.1 - 0.14 10.9 0.2 0.19 10.5 0.2 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Ribosomal_S27e PF01667.17 KIK38553.1 - 5.1 6.9 6.2 0.76 9.5 1.7 2.0 2 0 0 2 2 1 0 Ribosomal protein S27 WD40 PF00400.32 KIK38554.1 - 4.1e-40 135.0 30.3 7.3e-06 26.6 0.1 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KIK38554.1 - 1.3e-10 41.0 1.1 2.5e-10 40.1 1.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK38554.1 - 4e-10 39.3 0.7 8.6e-10 38.2 0.7 1.6 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KIK38554.1 - 3.4e-07 30.4 0.5 0.64 10.4 0.0 5.3 2 2 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK38554.1 - 4.5e-07 28.9 9.3 0.0067 15.1 0.1 5.3 3 1 3 6 6 6 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KIK38554.1 - 0.05 13.2 2.8 2.1 7.8 0.3 3.0 2 1 1 3 3 3 0 PQQ-like domain PALB2_WD40 PF16756.5 KIK38554.1 - 0.11 11.4 7.3 1.8 7.4 0.8 3.5 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Fungal_trans PF04082.18 KIK38556.1 - 1.3e-16 60.5 0.5 2.6e-16 59.5 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MSC PF09402.10 KIK38556.1 - 0.045 13.2 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Acetyltransf_3 PF13302.7 KIK38560.1 - 1.6e-08 35.3 0.0 2.5e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK38560.1 - 2.2e-06 27.9 0.0 3.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MFS_1 PF07690.16 KIK38561.1 - 4.9e-21 75.0 24.7 4.7e-16 58.7 10.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK38561.1 - 1.1e-06 27.8 3.7 1.1e-06 27.8 3.7 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter DUF5090 PF17009.5 KIK38561.1 - 0.0056 16.7 0.5 0.0056 16.7 0.5 2.2 3 1 0 3 3 3 1 Domain of unknown function (DUF5090) LapA_dom PF06305.11 KIK38561.1 - 0.95 9.3 0.0 0.95 9.3 0.0 3.5 4 1 0 4 4 4 0 Lipopolysaccharide assembly protein A domain GDA1_CD39 PF01150.17 KIK38562.1 - 1.8e-103 346.4 0.0 1.6e-102 343.3 0.0 1.9 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 KIK38562.1 - 0.0038 16.7 0.0 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family PWWP PF00855.17 KIK38563.1 - 0.14 12.5 0.1 23 5.5 0.1 2.6 2 0 0 2 2 2 0 PWWP domain Pro_isomerase PF00160.21 KIK38564.1 - 8e-53 178.9 0.0 8.9e-53 178.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_12 PF13424.6 KIK38566.1 - 1.8e-12 47.4 26.0 0.18 12.1 0.1 11.4 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_10 PF13374.6 KIK38566.1 - 2.4e-08 33.6 39.3 1.3 9.0 0.0 14.1 14 4 0 14 14 14 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIK38566.1 - 2.5e-06 27.8 8.1 6.1 7.9 0.0 9.8 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK38566.1 - 0.00014 21.7 6.7 13 6.1 0.0 9.0 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK38566.1 - 0.0018 18.2 7.1 3.3 8.0 0.0 7.6 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK38566.1 - 0.0046 16.7 17.6 5.2 7.1 0.0 11.0 13 0 0 13 13 12 1 Tetratricopeptide repeat AKAP7_NLS PF10469.9 KIK38566.1 - 0.0066 16.3 0.2 21 4.9 0.0 5.6 5 2 3 8 8 8 0 AKAP7 2'5' RNA ligase-like domain TPR_11 PF13414.6 KIK38566.1 - 0.013 15.2 0.0 13 5.5 0.0 5.0 7 0 0 7 7 7 0 TPR repeat TPR_17 PF13431.6 KIK38566.1 - 0.027 14.8 6.6 29 5.3 0.0 7.5 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK38566.1 - 0.04 14.1 0.1 35 5.0 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK38566.1 - 0.043 14.5 1.7 22 5.8 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat POTRA_2 PF08479.11 KIK38566.1 - 0.057 13.3 0.0 43 4.0 0.0 4.9 6 0 0 6 6 6 0 POTRA domain, ShlB-type Suv3_C_1 PF18147.1 KIK38566.1 - 2.6 8.0 10.3 1e+02 2.9 0.0 6.4 9 0 0 9 9 9 0 Suv3 C-terminal domain 1 Exo_endo_phos PF03372.23 KIK38567.1 - 0.00021 20.9 0.0 0.00034 20.2 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MYO10_CC PF16735.5 KIK38568.1 - 0.026 14.6 0.4 0.026 14.6 0.4 2.1 2 0 0 2 2 2 0 Unconventional myosin-X coiled coil domain SRPRB PF09439.10 KIK38568.1 - 0.068 12.6 2.6 0.71 9.3 0.4 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Ribosomal_L31e PF01198.19 KIK38568.1 - 0.076 13.3 2.6 0.98 9.7 0.2 2.6 2 0 0 2 2 2 0 Ribosomal protein L31e MitMem_reg PF13012.6 KIK38568.1 - 0.12 12.8 1.6 0.3 11.5 1.6 1.7 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function DUF4407 PF14362.6 KIK38568.1 - 0.14 11.5 2.1 0.23 10.8 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RVT_1 PF00078.27 KIK38569.1 - 2.7e-08 33.6 0.0 4.6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 KIK38571.1 - 1e-11 45.2 0.0 2.6e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 KIK38571.1 - 8.3e-05 23.2 0.2 0.00033 21.3 0.2 2.1 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-RING_2 PF13639.6 KIK38571.1 - 0.23 11.8 0.9 0.58 10.5 0.9 1.7 1 0 0 1 1 1 0 Ring finger domain ABC_tran PF00005.27 KIK38572.1 - 1.3e-24 87.3 0.0 3.9e-24 85.7 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIK38572.1 - 7.8e-10 39.0 0.1 0.00063 19.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIK38572.1 - 5.4e-08 32.9 0.1 0.00013 21.8 0.1 2.4 2 1 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 KIK38572.1 - 2.2e-06 27.2 0.2 0.075 12.5 0.6 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIK38572.1 - 0.00078 20.0 0.1 0.0014 19.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIK38572.1 - 0.0013 18.5 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KIK38572.1 - 0.012 16.0 0.0 0.051 13.9 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_27 PF13514.6 KIK38572.1 - 0.026 14.1 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KIK38572.1 - 0.029 14.6 0.1 0.068 13.4 0.1 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 KIK38572.1 - 0.034 14.0 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 KIK38572.1 - 0.044 13.1 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 KIK38572.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KIK38572.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit bZIP_1 PF00170.21 KIK38573.1 - 9.8e-12 44.8 13.0 1.6e-11 44.1 13.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 KIK38573.1 - 9.7e-06 25.5 0.0 9.7e-06 25.5 0.0 4.6 2 1 2 4 4 4 1 Transcription factor PAP1 bZIP_2 PF07716.15 KIK38573.1 - 0.0016 18.5 12.9 0.0016 18.5 12.9 2.2 1 1 1 2 2 2 1 Basic region leucine zipper DivIC PF04977.15 KIK38573.1 - 0.0087 15.8 1.4 0.017 14.9 1.4 1.4 1 0 0 1 1 1 1 Septum formation initiator SHE3 PF17078.5 KIK38573.1 - 0.017 14.9 3.8 0.03 14.1 3.8 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 GvpL_GvpF PF06386.11 KIK38573.1 - 0.96 9.3 3.9 1.5 8.7 3.9 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF XhlA PF10779.9 KIK38573.1 - 4.9 7.4 4.7 8.7 6.6 4.7 1.3 1 0 0 1 1 1 0 Haemolysin XhlA CCDC106 PF15794.5 KIK38573.1 - 5.6 6.6 11.3 17 5.1 11.3 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Erf4 PF10256.9 KIK38574.1 - 1.7e-30 105.5 0.1 2.5e-30 104.9 0.1 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Get5_bdg PF16843.5 KIK38574.1 - 0.13 11.8 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein TPR_1 PF00515.28 KIK38575.1 - 5.1e-54 178.0 25.2 2.7e-07 30.1 0.0 10.9 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KIK38575.1 - 4.4e-51 166.9 18.8 1.4e-05 24.9 0.2 10.7 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 KIK38575.1 - 2.2e-42 139.7 10.5 0.00049 20.1 1.6 10.8 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_14 PF13428.6 KIK38575.1 - 1e-29 100.7 8.7 0.0012 19.5 0.0 10.0 2 2 8 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.6 KIK38575.1 - 1e-29 102.8 8.0 1.2e-07 32.3 0.0 7.1 3 2 3 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 KIK38575.1 - 2.3e-27 95.1 14.0 3.5e-05 24.0 0.0 7.8 4 3 3 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 KIK38575.1 - 7.8e-25 87.2 10.2 0.00033 21.1 0.4 7.2 5 1 2 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.6 KIK38575.1 - 9.5e-25 85.2 11.0 0.0021 18.3 0.3 9.3 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 KIK38575.1 - 1.5e-24 85.4 25.2 3.5e-06 26.6 0.4 9.9 5 3 4 9 9 9 7 TPR repeat TPR_7 PF13176.6 KIK38575.1 - 6.9e-24 82.1 11.5 0.025 14.6 0.0 9.5 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_6 PF13174.6 KIK38575.1 - 2e-23 81.4 11.6 0.015 15.9 0.0 9.7 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 KIK38575.1 - 5.6e-15 55.2 10.6 0.067 13.3 0.1 7.1 2 2 6 8 8 8 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK38575.1 - 1.1e-10 41.6 7.3 5.9e-05 23.2 1.0 4.4 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KIK38575.1 - 4.7e-10 39.1 4.3 0.0021 17.3 0.7 5.4 1 1 6 7 7 7 5 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK38575.1 - 1.9e-06 27.5 0.6 0.00015 21.3 0.1 2.4 2 0 0 2 2 2 1 MalT-like TPR region TPR_21 PF09976.9 KIK38575.1 - 4.4e-06 26.5 7.9 0.022 14.5 0.2 3.9 3 2 0 3 3 3 2 Tetratricopeptide repeat-like domain SNAP PF14938.6 KIK38575.1 - 6.1e-05 22.6 6.4 0.11 11.8 0.2 4.2 1 1 1 4 4 4 2 Soluble NSF attachment protein, SNAP ChAPs PF09295.10 KIK38575.1 - 0.00018 20.6 0.0 0.3 10.0 0.0 2.4 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) RPN7 PF10602.9 KIK38575.1 - 0.0016 18.2 0.7 11 5.7 0.1 4.3 3 2 1 4 4 4 0 26S proteasome subunit RPN7 TPR_20 PF14561.6 KIK38575.1 - 0.0021 18.4 3.3 0.024 14.9 0.1 3.8 4 1 0 4 4 4 1 Tetratricopeptide repeat DUF4919 PF16266.5 KIK38575.1 - 0.0072 16.3 0.1 0.48 10.3 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4919) TPR_10 PF13374.6 KIK38575.1 - 0.011 15.6 15.0 0.67 9.9 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF2225 PF09986.9 KIK38575.1 - 0.022 14.5 1.1 2.5 7.8 0.1 3.4 1 1 3 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) Fis1_TPR_C PF14853.6 KIK38575.1 - 0.11 12.6 0.8 22 5.2 0.0 3.4 3 1 1 4 4 2 0 Fis1 C-terminal tetratricopeptide repeat Sel1 PF08238.12 KIK38575.1 - 0.41 11.4 2.3 19 6.1 0.0 3.4 3 0 0 3 3 2 0 Sel1 repeat TPR_3 PF07720.12 KIK38575.1 - 0.73 9.9 22.0 1.6 8.8 0.7 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat MIT PF04212.18 KIK38575.1 - 0.97 9.6 16.1 56 3.9 0.0 6.1 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 KIK38575.1 - 3.4 8.1 5.1 13 6.2 0.4 3.4 3 1 1 4 4 4 0 Bacterial transcriptional activator domain 4F5 PF04419.14 KIK38576.1 - 1.9e-07 31.8 12.1 3.3e-07 31.1 12.1 1.4 1 0 0 1 1 1 1 4F5 protein family Brr6_like_C_C PF10104.9 KIK38577.1 - 1.2e-45 154.5 0.7 1.5e-45 154.2 0.7 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain CLP_protease PF00574.23 KIK38578.1 - 8.1e-75 250.7 0.0 1.1e-74 250.3 0.0 1.1 1 0 0 1 1 1 1 Clp protease Regulator_TrmB PF11495.8 KIK38579.1 - 0.13 11.4 1.5 0.16 11.2 1.5 1.1 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB SAP30_Sin3_bdg PF13867.6 KIK38581.1 - 0.0045 17.3 0.5 0.041 14.2 0.2 2.1 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Chorismate_synt PF01264.21 KIK38582.1 - 2.9e-139 463.3 0.1 3.3e-139 463.1 0.1 1.0 1 0 0 1 1 1 1 Chorismate synthase UPF0052 PF01933.18 KIK38584.1 - 1e-25 90.6 0.0 1.3e-25 90.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Caf4 PF11615.8 KIK38586.1 - 0.11 12.4 0.6 0.71 9.9 0.0 2.2 1 1 1 2 2 2 0 CCR4-associated factor 4 WD40 PF00400.32 KIK38588.1 - 1.5e-30 104.8 12.0 2.1e-08 34.7 1.2 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38588.1 - 3.7e-19 68.8 0.6 0.00016 21.9 0.0 4.6 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK38588.1 - 2.8e-06 26.5 0.0 0.029 13.3 0.0 3.3 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK38588.1 - 3.1e-06 27.2 0.0 0.011 15.6 0.0 2.9 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 KIK38588.1 - 7.6e-05 21.8 1.8 0.012 14.5 0.1 2.5 3 0 0 3 3 3 2 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 KIK38588.1 - 0.00016 20.2 0.0 0.018 13.4 0.0 2.2 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 KIK38588.1 - 0.00076 18.9 0.1 0.018 14.4 0.0 2.5 1 1 1 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK38588.1 - 0.00093 18.0 0.3 9.5 4.7 0.0 3.8 1 1 2 4 4 4 2 Nucleoporin Nup120/160 Rav1p_C PF12234.8 KIK38588.1 - 0.022 13.2 0.0 0.028 12.8 0.0 1.1 1 0 0 1 1 1 0 RAVE protein 1 C terminal PD40 PF07676.12 KIK38588.1 - 0.031 14.2 0.1 40 4.3 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.6 KIK38588.1 - 0.035 14.1 0.1 0.91 9.6 0.0 2.9 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF1513 PF07433.11 KIK38588.1 - 0.18 10.9 0.2 10 5.1 0.0 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1513) WD40 PF00400.32 KIK38590.1 - 2.3e-18 66.2 7.5 1.8e-06 28.5 0.1 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38590.1 - 6.1e-08 32.9 0.2 0.0023 18.2 0.0 2.5 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Me-amine-dh_H PF06433.11 KIK38590.1 - 0.00094 18.1 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Methylamine dehydrogenase heavy chain (MADH) Frtz PF11768.8 KIK38590.1 - 0.0013 17.2 0.0 0.013 13.8 0.0 1.9 1 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KIK38590.1 - 0.0038 16.2 0.1 0.047 12.6 0.0 2.1 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 KIK38590.1 - 0.07 13.2 0.3 0.42 10.7 0.2 2.4 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DUF4917 PF16263.5 KIK38590.1 - 0.089 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4917) TPR_2 PF07719.17 KIK38591.1 - 2.4e-21 74.0 51.7 0.0045 17.0 0.1 14.0 15 0 0 15 15 15 6 Tetratricopeptide repeat TPR_19 PF14559.6 KIK38591.1 - 2e-20 73.0 46.6 0.00038 20.9 0.0 10.6 9 2 4 13 13 13 9 Tetratricopeptide repeat TPR_1 PF00515.28 KIK38591.1 - 3.3e-18 64.7 38.8 0.00018 21.2 0.1 11.5 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_14 PF13428.6 KIK38591.1 - 5.3e-12 45.5 54.3 0.011 16.5 0.6 14.9 11 5 5 16 16 14 5 Tetratricopeptide repeat TPR_12 PF13424.6 KIK38591.1 - 1.4e-11 44.5 34.7 0.0077 16.5 0.1 8.3 8 2 0 8 8 7 5 Tetratricopeptide repeat TPR_6 PF13174.6 KIK38591.1 - 9.1e-11 41.7 24.4 0.00081 19.9 0.2 10.4 11 0 0 11 11 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIK38591.1 - 4.9e-10 38.8 25.2 0.011 15.9 0.1 11.5 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK38591.1 - 8.9e-08 32.7 49.1 0.0029 18.2 2.6 11.0 11 1 1 12 12 11 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIK38591.1 - 1.8e-07 31.0 21.5 1.3 9.6 0.2 10.2 11 0 0 11 11 10 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK38591.1 - 1.5e-05 25.1 18.5 0.1 12.8 1.7 6.1 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KIK38591.1 - 0.0039 17.1 32.0 0.1 12.7 0.1 9.7 11 1 1 12 12 11 3 Tetratricopeptide repeat DUF2989 PF11207.8 KIK38591.1 - 0.0055 16.5 0.1 0.0055 16.5 0.1 5.3 5 1 0 5 5 4 1 Protein of unknown function (DUF2989) TPR_10 PF13374.6 KIK38591.1 - 0.01 15.7 0.6 0.01 15.7 0.6 10.1 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK38591.1 - 0.063 13.0 25.2 1.2 8.9 0.0 9.5 11 1 1 12 12 12 0 TPR repeat DUF4337 PF14235.6 KIK38591.1 - 0.63 10.2 9.2 2.4 8.2 9.2 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) TPR_4 PF07721.14 KIK38591.1 - 0.72 10.7 26.8 0.36 11.6 0.2 8.1 10 0 0 10 10 7 0 Tetratricopeptide repeat zf-HIT PF04438.16 KIK38592.1 - 7.4e-08 32.1 11.7 1e-07 31.7 11.7 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KIK38592.1 - 0.00061 19.8 11.1 0.00095 19.2 11.1 1.3 1 0 0 1 1 1 1 MYND finger Asp PF00026.23 KIK38594.1 - 2.3e-72 244.1 9.3 2.9e-72 243.8 9.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK38594.1 - 2.2e-11 44.3 12.6 8.7e-10 39.1 11.4 3.1 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Fungal_trans PF04082.18 KIK38596.1 - 3.1e-12 46.1 0.2 4.6e-12 45.5 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK38596.1 - 2.8e-07 30.5 13.4 2.8e-07 30.5 13.4 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MerR-DNA-bind PF09278.11 KIK38596.1 - 0.068 13.7 0.2 0.17 12.4 0.2 1.7 1 0 0 1 1 1 0 MerR, DNA binding FUSC_2 PF13515.6 KIK38599.1 - 1.4e-21 76.9 12.1 1.4e-21 76.9 12.1 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 KIK38599.1 - 3.1e-09 36.2 8.9 1.3e-08 34.1 6.5 2.2 2 0 0 2 2 2 1 Aluminium activated malate transporter ArAE_2 PF10334.9 KIK38599.1 - 1.2e-08 35.1 0.3 6e-08 32.8 0.1 2.0 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC PF04632.12 KIK38599.1 - 1.5e-07 30.4 21.4 3.9e-07 29.0 9.8 3.4 2 2 0 2 2 2 2 Fusaric acid resistance protein family C2 PF00168.30 KIK38600.1 - 0.00055 20.2 0.0 0.0009 19.5 0.0 1.3 1 0 0 1 1 1 1 C2 domain DUF1577 PF07614.11 KIK38600.1 - 0.0065 15.6 0.1 0.0092 15.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1577) NT-C2 PF10358.9 KIK38600.1 - 0.065 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins Alpha_TIF PF02232.15 KIK38601.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) SelP_N PF04592.14 KIK38601.1 - 7 6.0 12.2 10 5.4 12.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF3732 PF12532.8 KIK38603.1 - 0.19 11.3 0.3 0.25 10.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) RNase_H PF00075.24 KIK38605.1 - 8.6e-21 74.6 0.0 3.1e-20 72.8 0.0 2.0 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.6 KIK38605.1 - 3.5e-06 27.6 1.8 3.5e-06 27.6 1.8 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase HypA PF01155.19 KIK38605.1 - 0.11 12.5 0.2 0.77 9.8 0.2 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lyase_1 PF00206.20 KIK38606.1 - 1.2e-19 70.8 0.0 1.7e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KIK38606.1 - 3.3e-18 66.0 0.0 1.8e-17 63.6 0.0 2.2 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus VIT1 PF01988.19 KIK38607.1 - 1.4e-61 208.1 5.0 1.7e-61 207.8 5.0 1.1 1 0 0 1 1 1 1 VIT family DUF4389 PF14333.6 KIK38607.1 - 0.019 14.9 1.0 0.58 10.1 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) DUF2583 PF10762.9 KIK38607.1 - 0.23 11.9 1.6 3.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) Na_Ca_ex PF01699.24 KIK38609.1 - 6.2e-31 107.4 40.0 9.3e-21 74.4 16.6 3.5 2 1 1 3 3 3 2 Sodium/calcium exchanger protein DUF872 PF05915.12 KIK38609.1 - 0.1 12.8 5.5 3.9 7.7 0.1 3.5 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) PseudoU_synth_2 PF00849.22 KIK38612.1 - 2.8e-29 102.3 0.0 4e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase E1-E2_ATPase PF00122.20 KIK38615.1 - 1e-37 129.4 0.9 1e-37 129.4 0.9 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KIK38615.1 - 8.9e-32 110.3 3.4 8.9e-32 110.3 3.4 3.0 2 1 1 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KIK38615.1 - 1.4e-19 69.9 0.0 2.8e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KIK38615.1 - 1.7e-19 71.0 0.5 9.5e-10 39.1 0.0 3.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KIK38615.1 - 3.9e-08 32.9 0.0 7.7e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KIK38615.1 - 5.2e-08 32.9 0.9 8.5e-08 32.2 0.9 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIK38615.1 - 0.012 16.0 0.4 0.83 10.0 0.1 2.7 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KIK38617.1 - 1e-39 135.9 0.5 1e-39 135.9 0.5 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KIK38617.1 - 4.8e-30 104.6 2.0 4.8e-30 104.6 2.0 3.0 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KIK38617.1 - 1.6e-20 74.3 0.4 5.9e-11 43.1 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIK38617.1 - 1.7e-17 63.2 0.0 3.1e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KIK38617.1 - 1.7e-07 31.3 0.7 3.1e-07 30.4 0.7 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KIK38617.1 - 1.1e-05 25.0 0.0 2.3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 KIK38617.1 - 0.015 15.7 0.1 4.1 7.8 0.0 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase DUF2238 PF09997.9 KIK38617.1 - 0.015 15.1 0.6 1.2 9.0 0.0 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2238) Catalase PF00199.19 KIK38617.1 - 0.12 11.4 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 Catalase F-box PF00646.33 KIK38618.1 - 7.2e-07 28.9 0.2 1.4e-06 28.0 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK38618.1 - 1.7e-06 27.8 0.2 4.2e-06 26.5 0.2 1.7 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 KIK38618.1 - 1.2e-05 25.9 0.3 0.085 13.8 0.0 3.2 2 0 0 2 2 2 2 WD domain, G-beta repeat UIM PF02809.20 KIK38618.1 - 0.016 15.1 5.7 0.034 14.1 0.7 3.0 2 0 0 2 2 2 0 Ubiquitin interaction motif F-box_4 PF15966.5 KIK38618.1 - 0.025 14.5 0.1 0.053 13.4 0.1 1.5 1 0 0 1 1 1 0 F-box SWIB PF02201.18 KIK38620.1 - 5.3e-22 77.5 0.0 1.1e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain BAR PF03114.18 KIK38621.1 - 7.2e-45 153.5 13.3 1e-44 153.0 13.3 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KIK38621.1 - 2e-13 49.7 0.2 1.1e-12 47.3 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KIK38621.1 - 6.2e-12 45.2 0.0 1.1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIK38621.1 - 5.3e-10 38.8 0.0 1.3e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 KIK38621.1 - 6.6e-10 39.1 8.6 6.6e-10 39.1 8.6 1.5 2 0 0 2 2 2 1 BAR domain of APPL family P16-Arc PF04699.14 KIK38622.1 - 1.3e-52 178.2 0.0 1.4e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 KIK38622.1 - 0.024 14.9 0.0 0.036 14.4 0.0 1.2 1 0 0 1 1 1 0 Dip2/Utp12 Family TilS PF09179.11 KIK38624.1 - 0.023 15.2 0.2 1.6 9.3 0.0 2.6 2 1 1 3 3 3 0 TilS substrate binding domain WD40 PF00400.32 KIK38626.1 - 6.2e-31 106.0 15.6 8.5e-07 29.6 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38626.1 - 5.3e-16 58.7 0.1 0.00016 21.9 0.0 5.0 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK38626.1 - 2.6e-05 24.2 0.0 0.0094 15.8 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK38626.1 - 0.00019 21.3 0.6 6.7 6.8 0.0 4.5 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat WD40 PF00400.32 KIK38627.1 - 2.9e-40 135.5 9.8 8.2e-10 39.1 0.4 5.0 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38627.1 - 3.8e-11 43.1 0.0 0.035 14.4 0.0 4.4 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK38627.1 - 1.1e-08 34.4 0.0 0.32 9.9 0.0 4.2 3 1 1 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 KIK38627.1 - 2.1e-06 28.2 0.0 6.5e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK38627.1 - 7.8e-05 22.6 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.12 KIK38627.1 - 0.00066 19.6 3.7 4.5 7.3 0.0 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat APS_kinase PF01583.20 KIK38627.1 - 0.042 13.7 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.22 KIK38627.1 - 0.061 13.7 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase HD PF01966.22 KIK38628.1 - 1.4e-13 51.1 1.4 6.6e-13 48.9 0.1 2.6 3 1 1 4 4 4 1 HD domain TPR_12 PF13424.6 KIK38631.1 - 0.00048 20.3 3.4 0.2 12.0 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK38631.1 - 0.25 12.0 2.0 28 5.5 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat MFS_1 PF07690.16 KIK38632.1 - 2.4e-14 53.0 26.8 2.8e-14 52.8 24.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KIK38632.1 - 1.3e-13 51.1 7.2 2.5e-13 50.1 7.2 1.4 1 0 0 1 1 1 1 Nodulin-like Tcf25 PF04910.14 KIK38633.1 - 8.4e-103 344.1 0.0 1.2e-102 343.5 0.0 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_12 PF13424.6 KIK38633.1 - 0.0039 17.5 0.1 0.014 15.7 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK38633.1 - 0.0051 16.7 0.5 0.017 15.1 0.5 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK38633.1 - 0.0082 16.6 0.0 0.03 14.8 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK38633.1 - 0.0087 15.8 0.0 0.029 14.2 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIK38633.1 - 0.043 13.7 0.4 0.13 12.2 0.4 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK38633.1 - 0.05 14.4 1.9 0.29 12.0 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK38633.1 - 0.14 12.4 0.2 0.14 12.4 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat G-patch_2 PF12656.7 KIK38634.1 - 4.2e-20 71.6 0.4 2.5e-19 69.1 0.0 2.4 2 0 0 2 2 2 1 G-patch domain WD40 PF00400.32 KIK38635.1 - 6.4e-32 109.1 12.9 2.2e-05 25.1 0.0 9.1 9 0 0 9 9 9 7 WD domain, G-beta repeat HET PF06985.11 KIK38635.1 - 2e-12 47.7 3.3 6.6e-11 42.8 0.2 2.5 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) ANAPC4_WD40 PF12894.7 KIK38635.1 - 4.1e-08 33.4 0.1 0.062 13.6 0.0 4.4 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 KIK38635.1 - 1.7e-05 24.6 12.6 2.2 8.6 0.0 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK38635.1 - 9.9e-05 22.9 6.1 4.9 8.2 0.0 5.8 5 1 0 5 5 4 1 Tetratricopeptide repeat eIF2A PF08662.11 KIK38635.1 - 0.00014 21.8 0.1 1.6 8.5 0.0 3.6 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A TPR_1 PF00515.28 KIK38635.1 - 0.0002 21.0 6.6 51 3.9 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Ge1_WD40 PF16529.5 KIK38635.1 - 0.031 13.2 0.0 2.4 7.0 0.0 3.2 4 1 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_16 PF13432.6 KIK38635.1 - 0.032 14.9 13.0 1.1 9.9 0.5 5.0 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK38635.1 - 0.036 13.7 0.4 0.67 9.7 0.1 3.0 3 0 0 3 3 3 0 TPR repeat BTAD PF03704.17 KIK38635.1 - 3.5 8.0 7.4 17 5.8 0.1 4.1 3 2 1 4 4 4 0 Bacterial transcriptional activator domain zf-C2H2 PF00096.26 KIK38636.1 - 0.014 15.8 15.4 0.02 15.3 0.2 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KIK38636.1 - 5.8 6.8 12.2 5.9 6.7 1.4 2.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain RFC1 PF08519.12 KIK38638.1 - 8.2e-54 182.0 0.0 1.1e-52 178.4 0.0 2.5 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KIK38638.1 - 5.4e-15 55.5 0.0 2.4e-14 53.5 0.0 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KIK38638.1 - 1.8e-07 31.7 0.0 6.6e-07 29.8 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KIK38638.1 - 6.4e-05 22.9 0.3 0.00017 21.6 0.3 1.8 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 KIK38638.1 - 0.024 14.3 0.1 0.024 14.3 0.1 3.1 3 1 0 3 3 3 0 AAA domain AAA_14 PF13173.6 KIK38638.1 - 0.059 13.4 0.0 0.23 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_assoc_2 PF16193.5 KIK38638.1 - 0.094 13.1 0.0 0.32 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA C-terminal domain AAA_22 PF13401.6 KIK38638.1 - 0.11 12.8 0.1 1.1 9.5 0.1 2.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KIK38638.1 - 0.11 12.4 0.2 0.35 10.7 0.1 1.9 2 0 0 2 2 2 0 NTPase Spt5_N PF11942.8 KIK38638.1 - 4.9 8.2 19.8 19 6.3 3.0 3.7 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Bunya_NS-S_2 PF03231.13 KIK38639.1 - 0.18 10.5 0.1 0.21 10.4 0.1 1.0 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-S MMR_HSR1 PF01926.23 KIK38642.1 - 3e-07 30.5 0.0 6.7e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK38642.1 - 8.7e-06 25.7 0.0 0.0012 18.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 KIK38642.1 - 0.0049 16.2 0.0 0.042 13.1 0.0 2.0 2 0 0 2 2 2 1 Septin ABC_tran PF00005.27 KIK38642.1 - 0.015 15.8 0.0 0.03 14.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AIG1 PF04548.16 KIK38642.1 - 0.016 14.5 0.3 0.043 13.1 0.1 1.7 2 0 0 2 2 2 0 AIG1 family Roc PF08477.13 KIK38642.1 - 0.017 15.3 0.0 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KIK38642.1 - 0.042 14.4 0.3 0.23 12.0 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIK38642.1 - 0.056 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 KIK38642.1 - 0.068 12.3 0.0 2 7.5 0.1 2.2 2 0 0 2 2 2 0 G-protein alpha subunit IIGP PF05049.13 KIK38642.1 - 0.12 11.5 0.1 0.43 9.6 0.0 1.8 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 KIK38642.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NYD-SP28_assoc PF14775.6 KIK38642.1 - 0.2 11.8 0.3 0.47 10.6 0.1 1.7 2 0 0 2 2 2 0 Sperm tail C-terminal domain ATP_bind_1 PF03029.17 KIK38642.1 - 0.22 11.3 0.5 9 6.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Velvet PF11754.8 KIK38644.1 - 2.4e-57 194.8 0.7 1.1e-38 133.6 0.0 6.0 2 2 1 3 3 3 2 Velvet factor RNB PF00773.19 KIK38645.1 - 1.5e-94 317.0 0.0 2.1e-94 316.5 0.0 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 KIK38645.1 - 2.3e-24 85.8 0.0 4.6e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 KIK38645.1 - 2.4e-24 85.1 0.7 5.1e-24 84.1 0.7 1.6 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 KIK38645.1 - 2.4e-15 56.3 0.0 1.9e-14 53.4 0.0 2.6 3 0 0 3 3 3 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KIK38645.1 - 1.6e-09 38.2 0.1 6e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 PIN domain CSD2 PF17876.1 KIK38645.1 - 2.2e-09 37.4 2.1 0.00055 20.1 0.0 4.8 5 0 0 5 5 5 2 Cold shock domain OB_RNB PF08206.11 KIK38645.1 - 0.029 14.0 2.6 0.33 10.7 0.1 2.8 2 0 0 2 2 2 0 Ribonuclease B OB domain F-box-like PF12937.7 KIK38647.1 - 1.4e-06 28.1 1.1 9.6e-06 25.4 0.2 2.8 3 0 0 3 3 3 1 F-box-like FTH PF01827.27 KIK38647.1 - 0.16 11.8 0.2 3 7.6 0.2 2.4 1 1 0 1 1 1 0 FTH domain A_deaminase PF00962.22 KIK38650.1 - 1.1e-20 74.3 0.0 1.2e-10 41.3 0.0 2.4 2 1 0 2 2 2 2 Adenosine/AMP deaminase Cytochrom_C_2 PF01322.20 KIK38650.1 - 0.011 16.6 0.1 0.022 15.6 0.1 1.4 1 0 0 1 1 1 0 Cytochrome C' ELO PF01151.18 KIK38654.1 - 5.6e-60 203.0 24.3 6.7e-60 202.7 24.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF1422 PF07226.11 KIK38654.1 - 0.22 11.6 5.0 3 7.9 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) Glyco_hydro_38N PF01074.22 KIK38655.1 - 1.9e-57 194.8 0.4 4.4e-57 193.6 0.3 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_57 PF03065.15 KIK38655.1 - 0.0011 18.3 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Acyltransferase PF01553.21 KIK38656.1 - 2.4e-13 49.8 0.0 2e-05 24.2 0.0 3.0 3 0 0 3 3 3 2 Acyltransferase Peptidase_M24 PF00557.24 KIK38658.1 - 5.9e-50 169.9 0.0 7.6e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KIK38658.1 - 7.9e-16 58.1 6.5 1.4e-15 57.3 6.5 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding CEBP_ZZ PF16366.5 KIK38658.1 - 0.0057 16.9 0.7 0.0057 16.9 0.7 1.8 2 0 0 2 2 2 1 Cytoplasmic polyadenylation element-binding protein ZZ domain IF-2B PF01008.17 KIK38661.1 - 4e-58 196.9 0.0 1.1e-57 195.5 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family PAXNEB PF05625.11 KIK38662.1 - 0.17 11.0 0.0 0.17 11.0 0.0 1.0 1 0 0 1 1 1 0 PAXNEB protein Zn-ribbon_8 PF09723.10 KIK38662.1 - 4.2 7.6 9.5 15 5.8 3.1 2.6 1 1 1 2 2 2 0 Zinc ribbon domain Cyclin_N PF00134.23 KIK38663.1 - 8.8e-14 51.3 0.1 1.9e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KIK38663.1 - 0.00014 21.9 0.0 0.0099 16.0 0.0 2.5 2 1 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 KIK38663.1 - 0.00027 20.9 0.1 0.00096 19.1 0.0 1.9 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 KIK38663.1 - 0.097 13.1 0.0 0.17 12.3 0.0 1.6 1 1 0 1 1 1 0 Cyclin C-terminal domain Ribosomal_S21 PF01165.20 KIK38666.1 - 1.5e-12 47.0 10.1 1.5e-12 47.0 10.1 1.5 2 0 0 2 2 2 1 Ribosomal protein S21 RWD PF05773.22 KIK38667.1 - 7.3e-20 71.4 0.7 1.6e-19 70.3 0.7 1.6 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KIK38667.1 - 2e-07 31.4 7.2 2e-07 31.4 7.2 1.9 2 1 0 2 2 2 1 DRG Family Regulatory Proteins, Tma46 Abhydrolase_1 PF00561.20 KIK38668.1 - 1.6e-05 24.7 0.2 0.00013 21.7 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK38668.1 - 0.00014 21.3 0.0 0.00074 18.9 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 zf-CCCH PF00642.24 KIK38669.1 - 0.00031 20.6 4.7 0.00053 19.8 4.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Spectrin PF00435.21 KIK38669.1 - 0.14 12.6 1.1 0.31 11.5 0.2 2.0 2 1 0 2 2 2 0 Spectrin repeat zf-CCCH_2 PF14608.6 KIK38669.1 - 0.29 11.7 4.2 0.58 10.7 4.2 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Baculo_PEP_C PF04513.12 KIK38669.1 - 0.4 10.7 2.4 0.33 11.0 1.0 1.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-CCCH_4 PF18044.1 KIK38669.1 - 0.68 9.8 3.6 1.9 8.4 3.6 1.8 1 1 0 1 1 1 0 CCCH-type zinc finger Draxin PF15550.6 KIK38670.1 - 4.4 7.1 12.8 0.56 10.0 5.8 2.3 2 0 0 2 2 2 0 Draxin adh_short PF00106.25 KIK38671.1 - 1.2e-52 178.2 0.9 1.6e-52 177.8 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK38671.1 - 2.6e-34 118.8 0.3 3.3e-34 118.4 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK38671.1 - 5.7e-14 52.4 0.3 8.1e-14 51.9 0.3 1.2 1 0 0 1 1 1 1 KR domain Helicase_RecD PF05127.14 KIK38671.1 - 0.003 17.4 0.0 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 Helicase Epimerase PF01370.21 KIK38671.1 - 0.0073 15.8 0.3 0.016 14.7 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KIK38671.1 - 0.0093 16.2 0.4 0.016 15.5 0.4 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KIK38671.1 - 0.018 14.4 0.1 0.023 14.1 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 KIK38671.1 - 0.032 13.6 0.0 0.043 13.2 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 KIK38671.1 - 0.042 13.2 0.1 0.1 11.9 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 KIK38671.1 - 0.072 12.9 2.7 0.12 12.2 1.6 1.9 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.18 KIK38671.1 - 0.14 12.0 0.2 0.27 11.1 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rubis-subs-bind PF09273.11 KIK38672.1 - 0.0065 17.2 0.0 0.014 16.1 0.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding DnaJ PF00226.31 KIK38675.1 - 6.9e-21 74.1 0.5 2.7e-20 72.2 0.5 2.1 1 0 0 1 1 1 1 DnaJ domain Histone_HNS PF00816.21 KIK38675.1 - 0.2 12.5 11.6 0.074 13.9 8.0 2.2 2 0 0 2 2 2 0 H-NS histone family RAI16-like PF10257.9 KIK38676.1 - 2.8e-56 190.9 0.5 4.6e-56 190.2 0.5 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DUF913 PF06025.12 KIK38676.1 - 0.043 12.8 0.0 0.19 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) FAM176 PF14851.6 KIK38676.1 - 0.16 11.6 0.3 0.52 10.0 0.3 1.9 1 0 0 1 1 1 0 FAM176 family Spt5_N PF11942.8 KIK38676.1 - 1.8 9.6 10.0 5.3 8.1 7.1 2.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal zf_CopZ PF18423.1 KIK38677.1 - 0.038 13.9 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Zinc binding domain SHR-BD PF06650.12 KIK38678.1 - 0.095 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 SHR-binding domain of vacuolar-sorting associated protein 13 Gcn1_N PF12074.8 KIK38679.1 - 7.3e-86 288.7 0.9 7.3e-86 288.7 0.9 2.8 2 1 1 3 3 3 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 KIK38679.1 - 9.6e-23 78.3 15.4 0.055 13.7 0.1 15.7 18 0 0 18 18 17 5 HEAT repeat HEAT_EZ PF13513.6 KIK38679.1 - 6.6e-18 64.8 17.7 0.0011 19.5 0.1 13.8 13 2 4 17 17 16 4 HEAT-like repeat HEAT_2 PF13646.6 KIK38679.1 - 8.1e-18 64.6 29.2 0.00011 22.5 0.0 13.0 11 2 5 16 16 15 6 HEAT repeats CLASP_N PF12348.8 KIK38679.1 - 9.2e-11 41.7 0.0 0.0083 15.7 0.0 5.8 4 2 1 6 6 6 3 CLASP N terminal Cnd1 PF12717.7 KIK38679.1 - 2.2e-09 37.6 0.0 0.54 10.3 0.0 8.0 4 1 2 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KIK38679.1 - 7.5e-05 23.3 0.0 2.3 8.9 0.0 5.0 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 KIK38679.1 - 0.00033 20.8 5.3 6.6 7.0 0.0 6.7 9 0 0 9 9 9 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3437 PF11919.8 KIK38679.1 - 0.0016 18.3 2.7 0.25 11.3 0.0 5.1 5 0 0 5 5 5 1 Domain of unknown function (DUF3437) IFRD PF05004.13 KIK38679.1 - 0.0071 15.5 0.1 0.99 8.4 0.0 4.3 4 0 0 4 4 4 1 Interferon-related developmental regulator (IFRD) ADSL_C PF10397.9 KIK38679.1 - 0.39 11.3 2.4 23 5.6 0.0 4.4 4 0 0 4 4 4 0 Adenylosuccinate lyase C-terminus DUF2267 PF10025.9 KIK38679.1 - 1.3 9.3 5.0 28 5.0 0.1 4.7 3 2 2 5 5 5 0 Uncharacterized conserved protein (DUF2267) DUF1846 PF08903.11 KIK38679.1 - 1.6 7.2 3.2 0.56 8.7 0.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1846) DRIM PF07539.12 KIK38683.1 - 1.7e-168 561.8 20.6 1.7e-168 561.8 20.6 4.2 4 0 0 4 4 4 2 Down-regulated in metastasis MMS19_N PF14500.6 KIK38683.1 - 0.0013 18.4 0.4 0.0013 18.4 0.4 4.8 6 1 0 6 6 6 1 Dos2-interacting transcription regulator of RNA-Pol-II STAS_2 PF13466.6 KIK38683.1 - 0.053 13.9 0.6 1.1 9.6 0.1 3.6 3 0 0 3 3 3 0 STAS domain HEAT PF02985.22 KIK38683.1 - 1 9.8 14.3 29 5.3 0.4 7.6 9 0 0 9 9 9 0 HEAT repeat HEAT_EZ PF13513.6 KIK38683.1 - 5.9 7.5 22.8 5.1 7.7 0.2 8.1 8 0 0 8 8 8 0 HEAT-like repeat F-box-like PF12937.7 KIK38689.1 - 0.0021 17.9 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK38689.1 - 0.14 12.1 0.5 5.5 7.0 0.0 2.4 2 0 0 2 2 2 0 F-box domain DUF3487 PF11990.8 KIK38693.1 - 0.44 10.4 0.1 0.44 10.4 0.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3487) F-box-like PF12937.7 KIK38694.1 - 0.00026 20.8 0.0 0.00064 19.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK38694.1 - 0.0023 17.8 0.1 0.0069 16.2 0.1 1.9 1 0 0 1 1 1 1 F-box domain DNA_pol_B_exo2 PF10108.9 KIK38694.1 - 0.016 14.9 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RTP1_C2 PF10304.9 KIK38694.1 - 0.061 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 7TM_GPCR_Srd PF10317.9 KIK38694.1 - 0.18 10.9 0.1 0.28 10.3 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd CTP_transf_like PF01467.26 KIK38696.1 - 2.7e-23 82.7 0.0 3.9e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like HPS3_C PF14763.6 KIK38696.1 - 0.17 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, C-terminal Amidohydro_1 PF01979.20 KIK38697.1 - 2.7e-23 82.8 0.0 8.8e-15 54.8 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KIK38697.1 - 1.2e-08 34.9 0.4 1.9e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Claudin_2 PF13903.6 KIK38702.1 - 0.11 12.2 0.0 0.11 12.2 0.0 2.2 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Arrestin_C PF02752.22 KIK38703.1 - 3.9e-11 43.5 0.0 2.7e-10 40.8 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KIK38703.1 - 5.9e-11 42.6 0.0 4.5e-08 33.3 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Pro-kuma_activ PF09286.11 KIK38705.1 - 9.4e-44 149.2 0.1 1.6e-43 148.4 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain 4HBT_2 PF13279.6 KIK38707.1 - 1.4e-08 35.3 0.0 3.8e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 Thioesterase-like superfamily GIT_SHD PF08518.11 KIK38708.1 - 2.5e-26 91.0 3.3 1.8e-12 46.6 1.4 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Spc7 PF08317.11 KIK38708.1 - 0.58 9.0 18.3 0.69 8.7 10.0 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein Tropomyosin PF00261.20 KIK38708.1 - 0.61 9.4 28.5 2.1 7.6 28.5 2.1 1 1 0 1 1 1 0 Tropomyosin ADIP PF11559.8 KIK38708.1 - 0.66 10.1 17.8 2.1 8.4 2.5 2.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding ACCA PF03255.14 KIK38708.1 - 1.4 8.8 6.3 0.72 9.7 1.0 3.0 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF1664 PF07889.12 KIK38708.1 - 2 8.5 6.9 17 5.5 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 KIK38708.1 - 4.4 7.1 12.4 32 4.3 11.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) T2SSF PF00482.23 KIK38708.1 - 5.5 7.0 6.8 21 5.1 3.4 2.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF3496 PF12001.8 KIK38708.1 - 6.2 7.2 7.4 5.4 7.4 0.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3496) DUF4472 PF14739.6 KIK38708.1 - 7.7 7.3 14.4 14 6.4 0.7 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4472) Amidase PF01425.21 KIK38710.1 - 2.2e-81 274.1 0.0 5.8e-81 272.8 0.0 1.7 1 1 0 1 1 1 1 Amidase F-box-like PF12937.7 KIK38711.1 - 0.0011 18.8 0.3 0.0034 17.2 0.3 1.9 1 0 0 1 1 1 1 F-box-like PHD_Oberon PF07227.11 KIK38711.1 - 0.2 11.5 2.8 0.37 10.7 0.0 2.5 3 0 0 3 3 3 0 PHD - plant homeodomain finger protein p450 PF00067.22 KIK38713.1 - 3.7e-57 194.1 0.0 1.1e-56 192.5 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 RicinB_lectin_2 PF14200.6 KIK38714.1 - 3e-13 50.3 0.7 4.5e-09 36.9 1.0 2.2 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIK38714.1 - 7.7e-06 26.2 2.3 0.015 15.6 1.0 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Phage_holin_Dp1 PF16938.5 KIK38718.1 - 0.01 16.0 0.7 0.018 15.3 0.2 1.6 2 0 0 2 2 2 0 Putative phage holin Dp-1 RicinB_lectin_2 PF14200.6 KIK38720.1 - 5.2e-13 49.5 4.0 1e-08 35.8 1.5 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIK38720.1 - 2.6e-06 27.7 0.5 0.038 14.3 0.1 2.2 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain Urocanase PF01175.18 KIK38720.1 - 0.077 12.6 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Urocanase Rossmann-like domain EFG_IV PF03764.18 KIK38721.1 - 0.068 12.9 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Elongation factor G, domain IV Big_2 PF02368.18 KIK38723.1 - 0.076 12.9 0.1 0.093 12.6 0.1 1.1 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 2) Formyl_trans_N PF00551.19 KIK38726.1 - 3.8e-38 131.0 0.0 5.8e-37 127.2 0.0 2.0 1 1 0 1 1 1 1 Formyl transferase HLH PF00010.26 KIK38727.1 - 1e-10 41.4 0.3 2.4e-10 40.2 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nucleo_P87 PF07267.11 KIK38727.1 - 0.41 9.4 4.0 0.086 11.7 0.1 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 FXR_C1 PF16096.5 KIK38728.1 - 0.016 15.4 0.3 0.016 15.4 0.3 1.1 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 AtuA PF07287.11 KIK38729.1 - 0.16 10.7 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA DUF4081 PF13312.6 KIK38729.1 - 0.17 12.1 0.5 0.55 10.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4081) AP_endonuc_2 PF01261.24 KIK38733.1 - 2.5e-30 105.5 0.0 3.6e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel HSF_DNA-bind PF00447.17 KIK38734.1 - 1.6e-31 108.7 3.5 3.2e-31 107.8 3.5 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 KIK38734.1 - 6.8e-25 87.4 0.1 2e-24 85.9 0.2 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HALZ PF02183.18 KIK38734.1 - 1.7e-05 25.0 2.0 0.023 14.9 0.3 2.5 1 1 1 2 2 2 2 Homeobox associated leucine zipper SHE3 PF17078.5 KIK38734.1 - 0.02 14.6 0.6 0.038 13.7 0.6 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Scaffolding_pro PF11418.8 KIK38734.1 - 2.7 8.6 5.2 0.33 11.5 0.2 2.1 2 1 0 2 2 2 0 Phi29 scaffolding protein Cep57_CLD PF14073.6 KIK38734.1 - 8.2 6.4 7.6 0.88 9.6 0.3 2.7 3 0 0 3 3 3 0 Centrosome localisation domain of Cep57 ABC_tran PF00005.27 KIK38735.1 - 1.4e-26 93.7 0.0 3.2e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIK38735.1 - 1.4e-08 34.4 1.2 0.00025 20.6 0.1 2.2 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KIK38735.1 - 3e-05 23.9 0.0 4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KIK38735.1 - 9e-05 22.4 0.1 0.00021 21.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIK38735.1 - 0.00014 22.3 0.2 0.00044 20.7 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain Aldolase_II PF00596.21 KIK38735.1 - 0.00086 19.3 0.1 0.0016 18.4 0.1 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF218 PF02698.17 KIK38735.1 - 0.00088 19.3 0.0 0.019 15.0 0.1 2.4 2 0 0 2 2 2 1 DUF218 domain AAA_22 PF13401.6 KIK38735.1 - 0.0017 18.6 0.0 1.4 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 KIK38735.1 - 0.0018 18.5 0.0 0.0054 17.0 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KIK38735.1 - 0.0024 17.6 0.0 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KIK38735.1 - 0.0035 17.1 0.1 0.76 9.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 KIK38735.1 - 0.009 15.6 0.3 0.03 13.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KIK38735.1 - 0.017 15.6 0.0 0.042 14.3 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 KIK38735.1 - 0.04 14.1 0.0 0.089 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KIK38735.1 - 0.042 13.9 0.1 3.7 7.7 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_8 PF12780.7 KIK38735.1 - 0.048 13.0 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 AAA_13 PF13166.6 KIK38735.1 - 0.061 12.0 0.0 2.1 6.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain TgMIC1 PF11476.8 KIK38735.1 - 0.076 12.8 0.0 0.35 10.6 0.0 1.9 2 0 0 2 2 2 0 Toxoplasma gondii micronemal protein 1 TgMIC1 DEAD PF00270.29 KIK38735.1 - 0.085 12.6 0.1 0.99 9.1 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.6 KIK38735.1 - 0.099 13.2 0.0 0.45 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KIK38735.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain BTB PF00651.31 KIK38737.1 - 0.0015 18.7 0.0 0.017 15.3 0.0 2.1 1 1 0 2 2 2 1 BTB/POZ domain RPN7 PF10602.9 KIK38738.1 - 8.1e-50 168.9 0.0 1.2e-49 168.4 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KIK38738.1 - 3.8e-16 59.5 0.0 2.2e-15 57.0 0.0 2.2 2 0 0 2 2 2 1 PCI domain RPN6_N PF18055.1 KIK38739.1 - 8.9e-45 151.8 3.0 2.6e-44 150.3 3.0 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KIK38739.1 - 7.5e-18 65.0 0.3 3.2e-17 62.9 0.1 2.3 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 KIK38739.1 - 1.6e-10 40.5 1.0 4.9e-10 39.0 0.4 2.2 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_7 PF13176.6 KIK38739.1 - 4.8e-05 23.1 1.9 0.19 11.9 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat DDRGK PF09756.9 KIK38739.1 - 0.0085 15.7 2.4 0.031 13.9 0.1 2.2 2 0 0 2 2 2 1 DDRGK domain ANAPC5 PF12862.7 KIK38739.1 - 0.1 12.7 3.8 0.083 13.0 1.0 2.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 DUF1548 PF07579.11 KIK38739.1 - 1.1 9.6 5.8 1.7 9.0 0.1 3.4 2 2 1 3 3 3 0 Domain of Unknown Function (DUF1548) TPR_12 PF13424.6 KIK38740.1 - 0.0028 17.9 0.2 0.84 10.0 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK38740.1 - 0.029 15.2 0.2 9.1 7.4 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIK38740.1 - 0.047 14.1 0.4 3.9 8.1 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK38740.1 - 0.1 13.3 2.5 4.6 8.0 0.3 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KIK38740.1 - 0.22 11.7 2.8 2.2 8.5 0.7 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIK38741.1 - 5.4e-12 45.2 2.3 0.0043 16.9 0.0 4.8 4 2 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK38741.1 - 2.8e-07 30.7 1.8 0.35 11.2 0.2 4.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK38741.1 - 1.7e-06 27.6 0.9 2.4 8.1 0.0 4.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK38741.1 - 1.8e-06 27.6 1.3 3.3 8.0 0.0 4.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK38741.1 - 5e-05 23.0 1.9 0.61 10.3 0.0 4.5 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK38741.1 - 6.1e-05 22.9 0.0 0.74 10.2 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK38741.1 - 7.9e-05 23.2 0.1 3.6 8.7 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK38741.1 - 0.00058 19.5 0.0 20 5.0 0.0 3.7 4 0 0 4 4 4 0 TPR repeat Exonuc_VII_S PF02609.16 KIK38741.1 - 0.027 14.5 0.4 21 5.3 0.0 3.1 3 0 0 3 3 3 0 Exonuclease VII small subunit MIT PF04212.18 KIK38741.1 - 0.071 13.2 0.0 9.4 6.4 0.0 3.1 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Vta1_C PF18097.1 KIK38741.1 - 2.4 7.9 9.6 45 3.8 0.0 4.3 5 0 0 5 5 5 0 Vta1 C-terminal domain WD40 PF00400.32 KIK38743.1 - 2.7e-32 110.3 9.8 1.9e-05 25.3 0.1 8.1 8 0 0 8 8 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38743.1 - 4.6e-12 46.1 0.2 0.013 15.8 0.0 5.3 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 KIK38743.1 - 2.5e-10 39.6 13.8 2.8 8.3 0.1 8.6 9 0 0 9 9 8 2 Tetratricopeptide repeat HET PF06985.11 KIK38743.1 - 2e-09 37.9 4.6 1.8e-07 31.6 0.2 3.2 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) TPR_14 PF13428.6 KIK38743.1 - 7.3e-05 23.3 19.7 0.57 11.1 0.2 6.9 8 0 0 8 8 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK38743.1 - 9.2e-05 22.1 18.0 0.74 9.7 0.1 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat BTAD PF03704.17 KIK38743.1 - 0.015 15.7 9.2 0.68 10.4 0.5 3.4 1 1 1 2 2 2 0 Bacterial transcriptional activator domain Nup160 PF11715.8 KIK38743.1 - 0.019 13.6 1.5 0.13 10.9 0.0 2.6 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK38743.1 - 0.033 13.1 0.0 0.32 9.9 0.0 2.5 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MIT PF04212.18 KIK38743.1 - 0.15 12.2 0.3 78 3.4 0.1 3.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain PPR PF01535.20 KIK38743.1 - 0.19 12.0 1.2 62 4.2 0.0 4.2 3 0 0 3 3 3 0 PPR repeat TPR_17 PF13431.6 KIK38743.1 - 0.22 12.0 0.9 17 6.1 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK38743.1 - 0.53 10.4 13.2 1e+02 3.3 0.1 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK38743.1 - 0.74 10.4 16.3 1.2 9.7 0.7 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3856 PF12968.7 KIK38743.1 - 0.83 9.7 3.7 3.3 7.8 0.3 3.3 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_11 PF13414.6 KIK38743.1 - 1.4 8.7 8.8 1.7 8.4 0.3 4.5 5 0 0 5 5 5 0 TPR repeat TPR_6 PF13174.6 KIK38743.1 - 2.3 9.0 3.9 2.3e+02 2.8 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK38743.1 - 4.3 8.1 22.8 1.5 9.5 0.8 5.9 5 1 0 5 5 5 0 Tetratricopeptide repeat F-box-like PF12937.7 KIK38744.1 - 0.00087 19.1 0.1 0.0026 17.6 0.1 1.9 1 0 0 1 1 1 1 F-box-like RhoGEF PF00621.20 KIK38746.1 - 7.4e-36 124.1 0.8 2.1e-35 122.6 0.5 1.8 2 0 0 2 2 2 1 RhoGEF domain SH3_9 PF14604.6 KIK38746.1 - 5.6e-19 67.7 1.0 2.5e-08 33.7 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KIK38746.1 - 2.1e-18 65.7 2.6 2.7e-10 39.7 0.1 3.0 3 0 0 3 3 3 2 SH3 domain EF-hand_4 PF12763.7 KIK38746.1 - 1e-16 60.8 0.0 2.4e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand PH_13 PF16652.5 KIK38746.1 - 2.4e-11 43.7 1.4 3.4e-05 23.7 0.0 2.8 3 0 0 3 3 3 2 Pleckstrin homology domain WH2 PF02205.20 KIK38746.1 - 1.6e-08 34.1 0.3 3.5e-08 33.0 0.3 1.6 1 0 0 1 1 1 1 WH2 motif SH3_2 PF07653.17 KIK38746.1 - 1.7e-08 34.0 0.0 0.0038 16.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_1 PF00036.32 KIK38746.1 - 0.00026 20.3 0.0 0.073 12.6 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KIK38746.1 - 0.0093 16.4 0.0 0.029 14.8 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair PH PF00169.29 KIK38746.1 - 0.055 14.0 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 PH domain EF-hand_8 PF13833.6 KIK38746.1 - 0.09 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair IPK PF03770.16 KIK38747.1 - 3.8e-44 150.9 0.0 2.8e-43 148.1 0.0 2.0 1 1 0 1 1 1 1 Inositol polyphosphate kinase LRR_4 PF12799.7 KIK38748.1 - 1.2e-06 28.8 0.5 0.16 12.5 0.1 4.6 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KIK38748.1 - 0.001 18.9 1.2 20 5.6 0.2 5.6 6 0 0 6 6 6 1 Leucine Rich repeat Acyl_transf_1 PF00698.21 KIK38749.1 - 3.7e-22 79.2 0.0 7e-22 78.3 0.0 1.4 1 1 0 1 1 1 1 Acyl transferase domain Peroxin-3 PF04882.12 KIK38750.1 - 9.3e-95 318.3 0.4 1.1e-94 318.1 0.4 1.1 1 0 0 1 1 1 1 Peroxin-3 DEC-1_N PF04625.13 KIK38750.1 - 6 5.8 11.5 9.6 5.1 11.5 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region p450 PF00067.22 KIK38753.1 - 8.4e-61 206.1 0.0 1.4e-60 205.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 eIF2A PF08662.11 KIK38754.1 - 8.1e-78 260.8 0.0 4.6e-77 258.3 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.9 KIK38754.1 - 0.071 12.8 0.4 3.2 7.5 0.1 2.9 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature CDV3 PF15359.6 KIK38754.1 - 7.7 7.0 6.4 0.81 10.2 1.4 1.9 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 zf-C2H2 PF00096.26 KIK38756.1 - 4.5e-05 23.7 5.9 0.009 16.4 1.6 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 KIK38756.1 - 0.00028 21.5 0.8 0.00071 20.2 0.7 1.6 2 0 0 2 2 2 1 FOXP coiled-coil domain zf-Di19 PF05605.12 KIK38756.1 - 0.016 15.4 1.9 0.025 14.8 1.9 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.21 KIK38756.1 - 0.018 15.3 2.1 0.031 14.5 2.1 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2H2_4 PF13894.6 KIK38756.1 - 0.028 15.2 3.0 1.4 9.9 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4729 PF15866.5 KIK38756.1 - 0.096 12.0 0.6 0.12 11.6 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4729) zf-H2C2_5 PF13909.6 KIK38756.1 - 0.16 11.7 0.4 0.28 11.0 0.4 1.4 1 0 0 1 1 1 0 C2H2-type zinc-finger domain APH PF01636.23 KIK38760.1 - 4.3e-14 53.0 0.1 2e-13 50.9 0.0 2.1 3 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KIK38760.1 - 0.0058 16.0 0.0 0.22 10.9 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIK38760.1 - 0.055 13.1 0.0 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 RIO1 family NlpE_C PF17185.4 KIK38760.1 - 0.2 12.0 0.0 0.44 10.9 0.0 1.5 1 0 0 1 1 1 0 NlpE C-terminal OB domain Otopetrin PF03189.13 KIK38761.1 - 0.14 10.9 3.7 0.22 10.3 3.7 1.2 1 0 0 1 1 1 0 Otopetrin Hexokinase_2 PF03727.16 KIK38762.1 - 2.2e-84 282.6 0.0 3.1e-84 282.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KIK38762.1 - 1.7e-68 230.5 0.0 2.4e-68 230.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Ribosomal_L14 PF00238.19 KIK38763.1 - 2.3e-45 153.6 2.0 2.7e-45 153.4 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Atracotoxin PF05353.11 KIK38764.1 - 0.0031 17.5 1.4 0.0041 17.1 1.4 1.2 1 0 0 1 1 1 1 Delta Atracotoxin Stig1 PF04885.13 KIK38764.1 - 0.0096 16.4 3.0 0.013 16.0 3.0 1.2 1 0 0 1 1 1 1 Stigma-specific protein, Stig1 Toxin_12 PF07740.12 KIK38764.1 - 0.014 16.0 5.3 0.019 15.6 5.3 1.2 1 0 0 1 1 1 0 Ion channel inhibitory toxin Helicase_C PF00271.31 KIK38765.1 - 0.0013 19.1 0.0 0.0017 18.7 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CAP_N PF01213.19 KIK38765.1 - 3.2 7.2 5.7 3.7 7.0 5.7 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Plavaka PF18759.1 KIK38766.1 - 1.7e-118 395.6 1.7 2.2e-98 329.5 0.0 2.2 1 1 1 2 2 2 2 Plavaka transposase zf-C2H2 PF00096.26 KIK38767.1 - 0.022 15.2 0.1 0.069 13.6 0.1 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK38767.1 - 0.034 15.0 0.9 0.12 13.3 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-CGNR PF11706.8 KIK38767.1 - 0.071 13.0 1.0 7.6 6.5 0.1 2.2 2 0 0 2 2 2 0 CGNR zinc finger zf-C2H2_jaz PF12171.8 KIK38767.1 - 0.084 13.2 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding TipE PF16972.5 KIK38768.1 - 0.036 13.2 0.3 0.043 13.0 0.3 1.0 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE Plavaka PF18759.1 KIK38770.1 - 4e-82 276.0 0.1 4e-82 276.0 0.1 1.5 2 0 0 2 2 2 1 Plavaka transposase DDE_3 PF13358.6 KIK38771.1 - 8.3e-08 32.1 0.1 0.00016 21.5 0.0 2.6 2 0 0 2 2 2 2 DDE superfamily endonuclease Fer4_13 PF13370.6 KIK38771.1 - 0.0064 17.0 0.1 0.031 14.8 0.1 2.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Pkinase_fungal PF17667.1 KIK38772.1 - 2.6e-26 92.3 0.0 3.5e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK38772.1 - 0.053 13.4 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Oxygenase-NA PF09859.9 KIK38772.1 - 0.18 11.3 0.1 0.48 9.9 0.0 1.7 2 0 0 2 2 2 0 Oxygenase, catalysing oxidative methylation of damaged DNA RIO1 PF01163.22 KIK38772.1 - 0.26 10.9 0.9 0.38 10.3 0.1 1.6 2 1 0 2 2 2 0 RIO1 family Atracotoxin PF05353.11 KIK38774.1 - 0.0093 16.0 2.6 0.013 15.6 2.6 1.2 1 0 0 1 1 1 1 Delta Atracotoxin Toxin_12 PF07740.12 KIK38774.1 - 0.022 15.4 5.5 0.029 15.0 5.5 1.2 1 0 0 1 1 1 0 Ion channel inhibitory toxin Conotoxin_I2 PF17557.2 KIK38774.1 - 0.18 11.9 5.7 0.24 11.5 5.7 1.2 1 0 0 1 1 1 0 I2-superfamily conotoxins DUF4223 PF13978.6 KIK38774.1 - 1.4 8.9 5.2 2.5 8.1 5.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4223) AA_permease_2 PF13520.6 KIK38776.1 - 3.8e-17 62.2 15.7 5e-17 61.9 15.7 1.0 1 0 0 1 1 1 1 Amino acid permease CHAT PF12770.7 KIK38781.1 - 3.8e-32 111.9 0.1 7.8e-32 110.8 0.1 1.5 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 KIK38781.1 - 1.5e-08 34.8 12.7 1.1 9.7 0.2 8.4 5 3 3 8 8 8 4 Tetratricopeptide repeat TPR_10 PF13374.6 KIK38781.1 - 5.9e-07 29.2 24.8 0.01 15.7 0.0 9.1 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIK38781.1 - 0.0039 17.3 0.6 4.3 7.8 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIK38781.1 - 0.063 13.7 0.1 48 4.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK38781.1 - 0.064 13.1 12.2 4.6 7.2 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat Dehydratase_SU PF02287.15 KIK38781.1 - 0.069 13.2 0.1 4.1 7.5 0.1 2.5 2 0 0 2 2 2 0 Dehydratase small subunit AAA PF00004.29 KIK38786.1 - 0.00046 20.6 0.0 0.00085 19.8 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIK38786.1 - 0.0007 19.6 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIK38786.1 - 0.0017 18.8 0.0 0.013 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KIK38786.1 - 0.009 15.2 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 KIK38786.1 - 0.044 13.5 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KIK38786.1 - 0.15 12.6 0.0 0.28 11.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 KIK38786.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF4588 PF15251.6 KIK38788.1 - 0.00092 19.1 0.0 0.00092 19.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) POTRA_2 PF08479.11 KIK38788.1 - 0.19 11.5 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 POTRA domain, ShlB-type TPR_19 PF14559.6 KIK38789.1 - 2.7e-17 63.0 20.6 0.02 15.4 0.8 8.8 7 2 4 11 11 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 KIK38789.1 - 5e-14 51.2 16.7 0.11 12.6 0.1 11.7 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK38789.1 - 1.5e-10 41.2 21.6 0.00084 19.6 0.4 8.4 9 1 1 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIK38789.1 - 5.1e-10 38.8 12.8 0.11 12.8 0.0 10.9 13 0 0 13 13 12 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK38789.1 - 1.5e-09 38.3 14.9 0.52 11.0 0.0 8.2 7 2 2 9 9 9 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK38789.1 - 1.9e-09 37.0 7.8 0.36 10.7 0.0 9.1 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK38789.1 - 4.5e-09 36.1 1.0 4.4 7.9 0.0 6.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK38789.1 - 2.6e-08 33.4 3.5 0.22 11.3 0.0 5.8 6 0 0 6 6 6 3 TPR repeat TPR_6 PF13174.6 KIK38789.1 - 9.2e-08 32.2 7.9 0.31 11.8 0.1 9.1 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK38789.1 - 1.5e-07 31.6 18.5 4.5 8.4 0.1 10.1 8 3 3 11 11 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK38789.1 - 3.2e-07 29.9 11.3 0.29 11.2 0.1 7.6 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIK38789.1 - 2.2e-05 24.2 4.8 0.59 10.1 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK38789.1 - 4.9e-05 22.9 9.2 0.095 12.0 0.0 5.3 6 0 0 6 6 6 2 MalT-like TPR region TPR_20 PF14561.6 KIK38789.1 - 0.00014 22.1 3.5 0.38 11.1 0.5 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat ANAPC5 PF12862.7 KIK38789.1 - 0.0021 18.1 3.4 46 4.2 0.1 5.6 5 1 0 5 5 5 0 Anaphase-promoting complex subunit 5 TPR_4 PF07721.14 KIK38789.1 - 0.0054 17.2 0.2 0.96 10.3 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KIK38789.1 - 0.018 15.5 1.4 4 7.9 0.0 4.2 4 1 0 4 4 3 0 Alkyl sulfatase dimerisation SNAP PF14938.6 KIK38789.1 - 0.086 12.3 0.9 2 7.8 0.1 3.2 3 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_9 PF13371.6 KIK38789.1 - 0.091 12.9 8.7 0.26 11.5 0.1 4.8 4 1 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK38789.1 - 0.11 12.7 8.9 44 4.4 0.0 6.0 6 1 2 8 8 6 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN6_N PF18055.1 KIK38789.1 - 0.18 12.2 1.4 20 5.5 0.1 3.9 4 0 0 4 4 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain Tyrosinase PF00264.20 KIK38795.1 - 2e-27 96.9 0.1 2.8e-27 96.5 0.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Questin_oxidase PF14027.6 KIK38797.1 - 4.9e-86 289.3 0.0 5.8e-86 289.1 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like CNOT11 PF10155.9 KIK38799.1 - 5.3e-17 62.1 0.0 9.8e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 Pkinase PF00069.25 KIK38801.1 - 2.4e-72 243.5 0.6 2.4e-72 243.5 0.6 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK38801.1 - 1.6e-51 175.1 0.4 1.6e-51 175.1 0.4 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 KIK38801.1 - 2.2e-22 79.2 0.0 6.5e-22 77.7 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KIK38801.1 - 4.6e-06 26.2 0.0 7.8e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH PF00169.29 KIK38801.1 - 7.8e-06 26.4 1.0 1.7e-05 25.3 0.1 2.0 2 0 0 2 2 2 1 PH domain Haspin_kinase PF12330.8 KIK38801.1 - 2.9e-05 23.2 1.7 4.7e-05 22.5 1.7 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KIK38801.1 - 3.3e-05 22.9 1.8 3.9e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KIK38801.1 - 0.0047 16.9 8.1 0.0091 15.9 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KIK38801.1 - 0.075 12.1 0.1 0.16 11.0 0.1 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Adhesin_P1_N PF18652.1 KIK38801.1 - 0.18 11.8 2.9 0.12 12.4 0.8 1.8 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain TFIIA PF03153.13 KIK38801.1 - 1.7 8.6 13.1 2.4 8.1 13.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rrn6 PF10214.9 KIK38801.1 - 4.7 5.6 10.8 7.4 4.9 10.8 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Ribosomal_S19 PF00203.21 KIK38802.1 - 2.3e-26 91.5 0.0 3e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 zf-UDP PF14569.6 KIK38804.1 - 0.013 15.6 0.1 0.045 13.9 0.1 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger Peptidase_S41_N PF11918.8 KIK38804.1 - 0.04 14.1 2.2 23 5.2 0.2 3.3 1 1 2 3 3 3 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Nuc_deoxyri_tr2 PF15891.5 KIK38804.1 - 1.1 9.6 3.6 61 4.0 0.1 3.3 1 1 2 3 3 3 0 Nucleoside 2-deoxyribosyltransferase like TP_methylase PF00590.20 KIK38805.1 - 1.1e-41 143.2 1.0 1.1e-41 143.2 1.0 1.8 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 KIK38805.1 - 1.9e-11 44.3 0.0 3.7e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KIK38805.1 - 5.5e-08 32.3 2.6 3.9e-07 29.6 1.5 2.3 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KIK38805.1 - 6.2e-08 32.0 0.4 5.1e-07 29.0 0.0 2.8 2 1 1 3 3 3 1 Sirohaem biosynthesis protein central DRTGG PF07085.12 KIK38805.1 - 0.13 12.1 0.3 5.6 6.8 0.0 2.6 2 0 0 2 2 2 0 DRTGG domain Ank_2 PF12796.7 KIK38807.1 - 0.089 13.4 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) AAA PF00004.29 KIK38808.1 - 1.1e-05 25.8 0.0 2.6e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIK38808.1 - 0.0031 17.5 0.0 0.0056 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KIK38808.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KIK38808.1 - 0.021 14.6 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 KIK38808.1 - 0.038 14.4 0.0 2 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DUF815 PF05673.13 KIK38808.1 - 0.045 12.9 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 KIK38808.1 - 0.066 13.3 0.0 0.18 11.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain CPT PF07931.12 KIK38808.1 - 0.069 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 KIK38808.1 - 0.071 13.7 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KIK38808.1 - 0.081 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KIK38808.1 - 0.18 11.0 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain NTPase_1 PF03266.15 KIK38808.1 - 0.19 11.6 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 NTPase CHAT PF12770.7 KIK38812.1 - 6.1e-31 107.9 0.1 1.2e-30 106.9 0.1 1.5 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 KIK38812.1 - 7.6e-09 35.7 11.2 1.3 9.3 0.2 7.5 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 KIK38812.1 - 3.3e-06 26.7 4.2 1.1 9.5 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat MIT PF04212.18 KIK38812.1 - 1.2e-05 25.3 0.1 10 6.3 0.0 5.8 5 1 1 6 6 6 1 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 KIK38812.1 - 0.00042 20.0 3.7 21 5.2 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIK38812.1 - 0.00099 18.9 13.9 0.13 12.1 0.1 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK38812.1 - 0.0014 18.6 10.2 10 6.5 0.0 7.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK38812.1 - 0.056 13.7 1.2 55 4.4 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat GST_C_2 PF13410.6 KIK38812.1 - 0.44 10.6 2.1 32 4.7 0.1 2.9 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain TPR_11 PF13414.6 KIK38812.1 - 0.5 10.1 3.8 99 2.7 0.0 5.2 6 0 0 6 6 6 0 TPR repeat GGN PF15685.5 KIK38813.1 - 0.051 12.6 0.1 0.058 12.5 0.1 1.0 1 0 0 1 1 1 0 Gametogenetin HTH_Tnp_4 PF13613.6 KIK38815.1 - 0.0029 17.3 0.0 0.004 16.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_38 PF13936.6 KIK38815.1 - 0.04 13.7 0.0 0.058 13.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Exo_endo_phos_2 PF14529.6 KIK38820.1 - 1.5e-09 37.7 0.1 2e-09 37.3 0.1 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF1870 PF08965.10 KIK38822.1 - 0.1 12.6 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) Chromo PF00385.24 KIK38826.1 - 3e-05 23.8 0.1 3.2e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF5365 PF17326.2 KIK38829.1 - 0.1 13.0 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5365) DDE_1 PF03184.19 KIK38830.1 - 6.5e-21 74.7 0.0 1.2e-12 47.8 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease IL4Ra_N PF09238.10 KIK38830.1 - 0.17 12.3 0.8 0.43 10.9 0.8 1.7 1 1 0 1 1 1 0 Interleukin-4 receptor alpha chain, N-terminal KDZ PF18758.1 KIK38831.1 - 1.4e-13 51.0 0.4 1.2e-10 41.4 0.4 2.2 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIK38831.1 - 0.0037 17.4 1.4 0.01 16.0 1.0 1.9 1 1 1 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases UPF0449 PF15136.6 KIK38837.1 - 0.032 14.7 0.1 0.032 14.7 0.1 2.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 NOA36 PF06524.12 KIK38837.1 - 1.4 8.1 8.3 2 7.7 8.3 1.2 1 0 0 1 1 1 0 NOA36 protein Pkinase_fungal PF17667.1 KIK38838.1 - 1.8e-11 43.5 0.0 2e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Plavaka PF18759.1 KIK38839.1 - 0.016 14.4 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Plavaka transposase zf-CCHC PF00098.23 KIK38841.1 - 0.0011 19.0 4.7 1.3 9.2 1.4 3.5 2 1 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KIK38841.1 - 0.018 14.9 0.5 0.018 14.9 0.5 2.1 2 0 0 2 2 2 0 Zinc knuckle Ku_PK_bind PF08785.11 KIK38842.1 - 0.0072 16.5 0.1 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 Ku C terminal domain like RVT_1 PF00078.27 KIK38844.1 - 0.0001 21.9 0.0 0.00011 21.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KIK38848.1 - 0.0033 17.0 0.0 0.0034 16.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAM194 PF14977.6 KIK38849.1 - 0.0039 16.5 0.1 0.0044 16.4 0.1 1.0 1 0 0 1 1 1 1 FAM194 protein FAP206 PF12018.8 KIK38851.1 - 0.1 12.1 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function ABC_tran PF00005.27 KIK38854.1 - 2.2e-46 157.8 0.0 2e-27 96.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIK38854.1 - 6.3e-38 131.0 26.2 7.3e-24 84.9 3.3 3.4 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.19 KIK38854.1 - 8e-11 41.8 0.0 5.2e-05 22.8 0.9 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIK38854.1 - 0.0011 18.7 0.4 0.2 11.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KIK38854.1 - 0.0015 18.1 0.0 0.6 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIK38854.1 - 0.0018 18.6 1.2 3.6 7.9 0.0 3.4 3 1 0 3 3 3 2 AAA domain T2SSE PF00437.20 KIK38854.1 - 0.023 13.8 0.0 3.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.6 KIK38854.1 - 0.026 14.9 0.1 2.1 8.7 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain ATPase PF06745.13 KIK38854.1 - 0.03 13.7 0.3 3.1 7.1 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 KIK38854.1 - 0.047 13.4 0.1 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KIK38854.1 - 0.048 12.8 0.2 2.2 7.4 0.0 3.0 4 0 0 4 4 4 0 NB-ARC domain DUF87 PF01935.17 KIK38854.1 - 0.049 13.7 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_23 PF13476.6 KIK38854.1 - 0.05 14.1 0.0 7.9 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KIK38854.1 - 0.065 13.1 0.0 4.4 7.2 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase DUF4704 PF15787.5 KIK38854.1 - 0.12 11.6 0.3 0.24 10.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) cobW PF02492.19 KIK38854.1 - 1.5 8.4 3.6 1.2 8.7 0.5 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2076 PF09849.9 KIK38855.1 - 0.00025 21.2 2.3 0.00026 21.1 2.3 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KIK38855.1 - 0.0019 18.3 3.1 0.004 17.3 3.1 1.6 1 1 0 1 1 1 1 CHCH domain Paramyxo_NS_C PF02725.14 KIK38855.1 - 0.013 15.7 0.5 0.017 15.2 0.5 1.1 1 0 0 1 1 1 0 Non-structural protein C Tim44 PF04280.15 KIK38856.1 - 9.8e-05 22.5 0.6 0.00033 20.8 0.6 1.8 1 1 0 1 1 1 1 Tim44-like domain DUF3950 PF13132.6 KIK38856.1 - 4.2 7.2 8.3 2.6 7.9 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) Oxidored_molyb PF00174.19 KIK38858.1 - 1e-57 194.5 0.0 2.5e-57 193.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KIK38858.1 - 1.2e-48 164.6 0.2 2e-48 163.9 0.2 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 KIK38858.1 - 5e-27 94.1 0.0 9.1e-27 93.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KIK38858.1 - 2.3e-26 92.6 0.0 1.6e-25 89.9 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 KIK38858.1 - 1.4e-16 60.3 0.0 3.3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KIK38858.1 - 3.4e-05 24.0 0.1 0.00026 21.1 0.0 2.4 3 0 0 3 3 3 1 Ferric reductase NAD binding domain MFS_1 PF07690.16 KIK38859.1 - 5.8e-26 91.2 22.6 7e-26 91.0 22.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Pyr_redox_2 PF07992.14 KIK38860.1 - 2.3e-43 148.5 0.0 3.8e-43 147.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 KIK38860.1 - 7.9e-20 70.7 0.0 4.6e-19 68.3 0.0 2.2 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain NIR_SIR PF01077.22 KIK38860.1 - 2.8e-17 62.7 0.1 6.2e-17 61.5 0.0 1.7 2 0 0 2 2 2 1 Nitrite and sulphite reductase 4Fe-4S domain Fer2_BFD PF04324.15 KIK38860.1 - 4.3e-16 59.0 2.6 5.8e-13 49.0 1.9 2.8 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Pyr_redox PF00070.27 KIK38860.1 - 2.2e-13 50.6 0.4 7.1e-13 48.9 0.4 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR_ferr PF03460.17 KIK38860.1 - 7e-11 41.8 0.0 1.5e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.26 KIK38860.1 - 1.6e-10 40.8 0.2 1.4e-09 37.8 0.0 2.6 3 0 0 3 3 3 1 Rieske [2Fe-2S] domain Rubredoxin_C PF18267.1 KIK38860.1 - 2.2e-05 24.3 0.1 0.17 11.9 0.0 2.7 2 0 0 2 2 2 2 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox_3 PF13738.6 KIK38860.1 - 0.00058 19.2 0.0 0.096 11.9 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK38860.1 - 0.0034 16.5 2.7 0.84 8.7 0.0 3.1 2 1 1 3 3 3 2 FAD binding domain DAO PF01266.24 KIK38860.1 - 0.006 16.2 0.2 13 5.2 0.0 3.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.22 KIK38860.1 - 0.024 13.7 0.6 26 3.8 0.2 3.2 3 0 0 3 3 3 0 Glucose inhibited division protein A HI0933_like PF03486.14 KIK38860.1 - 0.064 12.0 0.1 1.1 7.9 0.0 2.7 2 1 2 4 4 4 0 HI0933-like protein FERM_N PF09379.10 KIK38860.1 - 0.072 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 FERM N-terminal domain AlaDh_PNT_C PF01262.21 KIK38860.1 - 0.079 12.2 0.2 0.13 11.5 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KIK38860.1 - 0.52 10.3 1.9 2.8 7.9 0.1 2.8 2 1 1 3 3 3 0 FAD-NAD(P)-binding EXS PF03124.14 KIK38861.1 - 7.5e-56 189.8 24.2 6.2e-53 180.3 14.6 2.1 1 1 1 2 2 2 2 EXS family SPX PF03105.19 KIK38861.1 - 2.8e-43 149.3 0.7 1.1e-42 147.3 0.7 1.8 1 1 0 1 1 1 1 SPX domain Glyco_transf_8C PF08437.10 KIK38861.1 - 0.45 10.6 2.4 12 6.1 0.7 3.2 3 0 0 3 3 3 0 Glycosyl transferase family 8 C-terminal HAD_2 PF13419.6 KIK38862.1 - 3.2e-06 27.3 0.0 0.084 13.0 0.0 3.1 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK38862.1 - 0.0015 18.8 0.0 0.0024 18.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIK38862.1 - 0.039 14.0 0.0 0.089 12.9 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like Syntaxin-6_N PF09177.11 KIK38863.1 - 1.2e-23 83.5 1.7 2.5e-22 79.3 0.0 2.4 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KIK38863.1 - 4.3e-12 45.8 1.2 4.3e-12 45.8 1.2 1.8 2 0 0 2 2 2 1 SNARE domain XhlA PF10779.9 KIK38863.1 - 0.0021 18.2 0.7 0.024 14.8 0.2 2.4 2 0 0 2 2 2 1 Haemolysin XhlA Use1 PF09753.9 KIK38863.1 - 0.0063 16.3 0.0 0.011 15.4 0.0 1.6 2 0 0 2 2 2 1 Membrane fusion protein Use1 DUF3040 PF11239.8 KIK38863.1 - 0.0081 16.4 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) HMMR_N PF15905.5 KIK38863.1 - 0.026 14.0 0.6 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal FliJ PF02050.16 KIK38863.1 - 0.036 14.3 2.0 0.47 10.7 1.0 2.5 2 1 0 2 2 2 0 Flagellar FliJ protein FlaC_arch PF05377.11 KIK38863.1 - 0.054 13.9 4.9 22 5.5 0.1 4.1 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Prominin PF05478.11 KIK38863.1 - 0.065 11.2 0.2 0.16 9.9 0.0 1.6 2 0 0 2 2 2 0 Prominin Snapin_Pallidin PF14712.6 KIK38863.1 - 0.092 13.2 1.4 3.5 8.1 0.5 2.4 2 0 0 2 2 2 0 Snapin/Pallidin APG17 PF04108.12 KIK38863.1 - 0.21 10.7 3.2 1.4 7.9 1.1 2.1 2 0 0 2 2 2 0 Autophagy protein Apg17 Laminin_II PF06009.12 KIK38863.1 - 0.27 11.2 1.8 10 6.1 0.2 2.4 2 1 0 2 2 2 0 Laminin Domain II Jnk-SapK_ap_N PF09744.9 KIK38863.1 - 0.81 9.9 5.0 1.3 9.2 0.1 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF5446 PF17522.2 KIK38863.1 - 2 8.7 5.3 0.55 10.4 0.5 2.4 3 0 0 3 3 2 0 Family of unknown function (DUF5446) RFC1 PF08519.12 KIK38866.1 - 4.5e-46 156.9 0.0 5.2e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain EzrA PF06160.12 KIK38869.1 - 0.0063 14.7 0.8 0.008 14.4 0.8 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Mer2 PF09074.10 KIK38869.1 - 0.016 15.0 2.4 0.027 14.3 2.4 1.3 1 0 0 1 1 1 0 Mer2 DUF745 PF05335.13 KIK38869.1 - 0.041 13.6 4.7 0.095 12.4 4.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Oscp1 PF10188.9 KIK38869.1 - 0.071 13.2 1.1 0.14 12.3 0.9 1.7 1 1 1 2 2 2 0 Organic solute transport protein 1 AvrB_AvrC PF05394.11 KIK38869.1 - 0.087 12.0 0.7 0.13 11.5 0.7 1.2 1 0 0 1 1 1 0 Avirulence protein DUF3450 PF11932.8 KIK38869.1 - 0.11 11.8 4.1 0.04 13.2 1.8 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) PMEI PF04043.15 KIK38869.1 - 0.12 12.7 4.2 0.4 11.0 4.2 1.9 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Minor_capsid_3 PF12691.7 KIK38869.1 - 0.14 12.5 0.6 0.34 11.3 0.5 1.7 1 1 0 1 1 1 0 Minor capsid protein from bacteriophage GatB_Yqey PF02637.18 KIK38869.1 - 0.24 11.3 2.6 0.47 10.3 2.6 1.5 1 0 0 1 1 1 0 GatB domain DUF2009 PF09418.10 KIK38869.1 - 0.61 9.1 2.5 0.77 8.8 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) zf-CCHC PF00098.23 KIK38871.1 - 0.23 11.6 0.8 0.23 11.6 0.8 4.4 5 0 0 5 5 5 0 Zinc knuckle zf-RVT PF13966.6 KIK38873.1 - 0.00061 20.5 0.1 0.00093 19.9 0.1 1.5 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase WD40 PF00400.32 KIK38876.1 - 5.3e-11 42.9 5.0 0.00059 20.6 0.1 4.4 4 1 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38876.1 - 2.9e-07 30.7 0.3 0.038 14.3 0.0 3.8 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK38876.1 - 0.0003 20.6 1.5 4.4 7.4 0.0 3.8 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK38876.1 - 0.056 12.1 0.5 0.58 8.7 0.0 2.5 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PUA PF01472.20 KIK38876.1 - 0.086 12.8 0.0 5.2 7.1 0.0 2.4 2 0 0 2 2 2 0 PUA domain DUF5570 PF17731.1 KIK38876.1 - 0.088 12.9 0.1 0.36 10.9 0.0 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5570) AA_permease_2 PF13520.6 KIK38881.1 - 0.029 13.2 0.0 0.032 13.1 0.0 1.0 1 0 0 1 1 1 0 Amino acid permease DUF4999 PF16390.5 KIK38883.1 - 0.16 12.2 0.0 0.2 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function SKG6 PF08693.10 KIK38884.1 - 0.00084 18.7 0.6 0.002 17.5 0.6 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 KIK38884.1 - 0.0059 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Mucin15 PF15672.5 KIK38884.1 - 0.037 13.5 26.7 0.06 12.8 26.7 1.3 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 NICE-1 PF15845.5 KIK38884.1 - 1.2 10.0 0.0 1.2 10.0 0.0 4.6 2 1 1 4 4 4 0 Cysteine-rich C-terminal 1 family Gram_pos_anchor PF00746.21 KIK38884.1 - 1.8 8.6 5.7 1.4 8.9 0.2 2.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif TMEM213 PF15192.6 KIK38888.1 - 0.13 12.3 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 TMEM213 family RasGEF_N PF00618.20 KIK38890.1 - 2.2e-15 56.8 0.3 1.7e-14 54.0 0.1 2.6 3 1 0 3 3 3 1 RasGEF N-terminal motif RasGEF PF00617.19 KIK38890.1 - 9.2e-15 55.3 0.0 5e-14 52.9 0.0 2.3 2 0 0 2 2 2 1 RasGEF domain WD40 PF00400.32 KIK38891.1 - 2.3e-20 72.5 15.0 2.4e-08 34.5 1.0 7.0 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38891.1 - 1.3e-13 51.1 0.4 0.012 15.9 0.0 6.2 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK38891.1 - 3.8e-06 26.7 5.4 2.2 8.3 0.0 6.2 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK38891.1 - 5.7e-05 22.0 0.1 0.26 9.9 0.0 3.7 2 1 2 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK38891.1 - 0.019 14.8 0.4 0.11 12.3 0.0 2.4 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A PQQ PF01011.21 KIK38891.1 - 0.029 14.3 0.4 1.3e+02 2.7 0.0 5.0 5 0 0 5 5 5 0 PQQ enzyme repeat PQQ_3 PF13570.6 KIK38891.1 - 0.047 14.2 3.9 31 5.2 1.4 5.0 5 0 0 5 5 5 0 PQQ-like domain Ge1_WD40 PF16529.5 KIK38891.1 - 0.069 12.1 0.0 0.57 9.1 0.0 2.4 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein NUDE_C PF04880.13 KIK38891.1 - 0.22 12.0 3.3 0.39 11.2 3.3 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Kelch_2 PF07646.15 KIK38891.1 - 0.41 10.7 2.8 5.7 7.1 0.1 3.9 4 1 0 4 4 4 0 Kelch motif SKG6 PF08693.10 KIK38892.1 - 0.0004 19.7 1.0 0.0011 18.3 1.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 KIK38892.1 - 0.13 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2207 PF09972.9 KIK38892.1 - 0.16 10.7 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) HET PF06985.11 KIK38894.1 - 5.2e-12 46.3 1.0 2.6e-08 34.3 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF485 PF04341.12 KIK38900.1 - 0.051 13.5 0.3 0.051 13.5 0.3 2.7 1 1 2 3 3 3 0 Protein of unknown function, DUF485 DUF3382 PF11862.8 KIK38900.1 - 0.27 11.6 4.9 0.42 10.9 3.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3382) Exo70 PF03081.15 KIK38904.1 - 1.5e-42 146.0 0.0 2.6e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Nsp1_C PF05064.13 KIK38904.1 - 0.0019 18.0 0.1 0.023 14.5 0.2 2.5 2 0 0 2 2 2 1 Nsp1-like C-terminal region Snapin_Pallidin PF14712.6 KIK38904.1 - 0.048 14.1 4.3 0.048 14.1 2.0 2.3 2 0 0 2 2 2 0 Snapin/Pallidin S6PP_C PF08472.10 KIK38904.1 - 0.089 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal CCT_2 PF09425.10 KIK38904.1 - 0.13 12.1 1.2 1 9.3 0.2 2.3 2 0 0 2 2 2 0 Divergent CCT motif Occludin_ELL PF07303.13 KIK38904.1 - 0.45 11.3 2.8 25 5.6 0.2 2.5 2 0 0 2 2 2 0 Occludin homology domain Baculo_PEP_C PF04513.12 KIK38904.1 - 1.8 8.6 6.6 3.6 7.6 1.5 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus BTB PF00651.31 KIK38905.1 - 1.5e-08 34.8 0.0 2.8e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain IBR PF01485.21 KIK38906.1 - 4e-09 36.6 35.5 4.9e-06 26.7 12.4 3.5 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_11 PF17123.5 KIK38906.1 - 0.016 14.9 1.5 0.016 14.9 1.5 2.4 2 0 0 2 2 2 0 RING-like zinc finger Robl_LC7 PF03259.17 KIK38908.1 - 1.2e-06 28.2 0.0 9.8e-06 25.3 0.0 1.9 1 1 0 1 1 1 1 Roadblock/LC7 domain Aldo_ket_red PF00248.21 KIK38909.1 - 2e-66 224.2 0.0 2.2e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Chs7 PF12271.8 KIK38910.1 - 2.8e-80 269.7 11.3 3.3e-80 269.5 11.3 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Sterol_MT_C PF08498.10 KIK38913.1 - 1.7e-28 98.7 0.1 2.9e-28 98.0 0.1 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KIK38913.1 - 1.5e-17 64.0 0.0 2.7e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK38913.1 - 1.7e-17 63.6 0.0 2.4e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK38913.1 - 1.4e-15 57.8 0.0 2.4e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KIK38913.1 - 6.4e-14 51.9 0.0 9.1e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KIK38913.1 - 3.3e-11 43.8 0.0 1.1e-10 42.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK38913.1 - 4.8e-10 39.5 0.0 6.6e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK38913.1 - 1.1e-06 28.1 0.0 1.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KIK38913.1 - 0.00028 20.7 0.0 0.00043 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 KIK38913.1 - 0.0014 18.2 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 KIK38913.1 - 0.0019 17.9 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_3 PF01596.17 KIK38913.1 - 0.002 17.4 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.14 KIK38913.1 - 0.0043 16.6 0.0 0.0089 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KIK38913.1 - 0.0056 16.3 0.0 0.0091 15.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.6 KIK38913.1 - 0.0084 17.1 0.0 0.031 15.3 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KIK38913.1 - 0.021 14.3 0.0 0.068 12.6 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.18 KIK38913.1 - 0.04 13.2 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain GCD14 PF08704.10 KIK38913.1 - 0.044 13.5 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.13 KIK38913.1 - 0.046 13.1 0.0 0.073 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KIK38913.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GPP34 PF05719.11 KIK38914.1 - 1.1e-66 224.8 0.6 1.3e-66 224.5 0.6 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) G-alpha PF00503.20 KIK38915.1 - 7.4e-109 364.2 0.3 8.5e-109 364.0 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK38915.1 - 1.3e-11 44.3 0.1 4.6e-08 32.7 0.0 2.8 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KIK38915.1 - 0.0061 16.8 0.0 1.5 9.0 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KIK38915.1 - 0.057 12.8 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein PRK PF00485.18 KIK38915.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GTP_EFTU PF00009.27 KIK38915.1 - 0.066 12.8 0.0 8.3 5.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 KIK38915.1 - 0.066 13.0 0.1 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KIK38915.1 - 0.084 13.1 0.0 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KIK38915.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF3349 PF11829.8 KIK38916.1 - 0.0088 16.8 0.1 0.061 14.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3349) DUF4646 PF15496.6 KIK38917.1 - 1.4e-19 71.0 0.0 1.8e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) DUF3761 PF12587.8 KIK38918.1 - 0.15 12.5 1.3 0.27 11.7 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3761) HET PF06985.11 KIK38919.1 - 2.8e-11 44.0 2.9 5.1e-08 33.4 0.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF4940 PF16298.5 KIK38919.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4940) DUF3602 PF12223.8 KIK38923.1 - 5.8e-20 71.7 34.9 8.7e-08 32.7 3.9 5.0 1 1 5 6 6 6 6 Protein of unknown function (DUF3602) KRE1 PF17056.5 KIK38923.1 - 0.029 14.1 0.1 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Killer toxin-resistance protein 1 Peptidase_M28 PF04389.17 KIK38924.1 - 1.3e-28 100.1 0.0 1.9e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIK38924.1 - 3.9e-09 36.5 0.0 6.9e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KIK38925.1 - 2e-27 96.2 0.0 3.2e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIK38925.1 - 9.7e-09 35.2 0.0 1.5e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF309 PF03745.14 KIK38925.1 - 0.16 11.6 0.1 0.79 9.5 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF309) AA_permease PF00324.21 KIK38926.1 - 1.5e-108 363.4 38.4 2e-108 363.1 38.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK38926.1 - 1.5e-24 86.6 40.8 2.2e-24 86.1 40.8 1.2 1 0 0 1 1 1 1 Amino acid permease Condensation PF00668.20 KIK38927.1 - 0.00014 20.7 0.5 0.16 10.6 0.0 2.9 3 0 0 3 3 3 2 Condensation domain DUF4451 PF14616.6 KIK38929.1 - 0.028 14.6 0.1 0.045 14.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) WD40 PF00400.32 KIK38931.1 - 7.9e-46 153.1 17.3 3.2e-07 30.9 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38931.1 - 5.3e-17 61.9 0.2 0.018 15.3 0.0 5.2 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK38931.1 - 1.1e-07 31.0 0.1 0.11 11.2 0.0 4.5 3 1 1 5 5 5 3 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK38931.1 - 2.9e-05 23.6 0.6 0.28 10.5 0.0 3.6 2 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 KIK38931.1 - 3.4e-05 23.0 0.0 10 5.0 0.0 4.5 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK38931.1 - 0.026 13.8 0.0 11 5.3 0.0 3.3 2 2 0 3 3 3 0 WD40-like domain Citrate_bind PF16114.5 KIK38933.1 - 1.1e-87 292.2 0.0 1.8e-87 291.4 0.0 1.4 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 KIK38933.1 - 6.9e-18 64.8 0.1 3.1e-15 56.1 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 KIK38933.1 - 1.4e-14 54.2 0.0 2.3e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 KIK38933.1 - 2.1e-13 50.8 0.0 4.6e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 KIK38933.1 - 4.6e-06 26.4 0.0 9.1e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 KIK38933.1 - 5.8e-06 26.1 0.0 2.1e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain WD40 PF00400.32 KIK38934.1 - 7.2e-43 143.8 26.1 7.1e-07 29.8 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38934.1 - 3.2e-14 53.0 0.6 0.00097 19.4 0.1 5.0 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK38934.1 - 4.4e-06 25.6 0.3 0.016 13.9 0.1 3.0 2 2 0 2 2 2 2 Nucleoporin Nup120/160 WW PF00397.26 KIK38934.1 - 1.2e-05 25.3 0.3 1.2e-05 25.3 0.3 3.4 4 0 0 4 4 4 1 WW domain WD40_like PF17005.5 KIK38934.1 - 0.069 12.5 0.0 31 3.8 0.0 3.0 2 1 1 3 3 3 0 WD40-like domain Ge1_WD40 PF16529.5 KIK38934.1 - 0.083 11.8 0.1 9.7 5.0 0.0 3.3 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KIK38935.1 - 8.5e-28 96.1 13.1 6.5e-08 33.1 0.6 5.1 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK38935.1 - 3.5e-12 46.5 0.1 4.2e-05 23.8 0.0 3.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK38935.1 - 0.12 11.3 0.0 2.3 7.1 0.0 2.3 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cellulase PF00150.18 KIK38937.1 - 6.7e-12 45.4 0.0 2.7e-11 43.4 0.0 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) WGR PF05406.15 KIK38938.1 - 0.083 13.0 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 WGR domain Hydrophobin PF01185.18 KIK38939.1 - 4.5e-19 68.8 10.6 5.3e-19 68.6 10.6 1.0 1 0 0 1 1 1 1 Fungal hydrophobin Macoilin PF09726.9 KIK38940.1 - 2 6.9 4.0 2.7 6.4 4.0 1.1 1 0 0 1 1 1 0 Macoilin family TGT PF01702.18 KIK38942.1 - 9.1e-34 117.1 0.0 1.9e-18 66.8 0.0 2.1 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase RAP1 PF07218.11 KIK38948.1 - 3.3 5.9 5.9 4.2 5.5 5.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.25 KIK38949.1 - 7.9e-41 140.2 0.0 1.2e-28 100.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK38949.1 - 3.5e-22 79.0 0.0 4.7e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK38949.1 - 0.00012 21.1 0.0 0.00018 20.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK38949.1 - 0.00028 20.9 0.5 0.00052 20.0 0.5 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK38949.1 - 0.066 12.5 0.0 0.14 11.5 0.0 1.5 2 0 0 2 2 2 0 Kinase-like zf-MYND PF01753.18 KIK38950.1 - 2.3e-05 24.4 17.7 5.1e-05 23.3 17.7 1.6 1 0 0 1 1 1 1 MYND finger Na_Ca_ex PF01699.24 KIK38951.1 - 5.3e-38 130.3 35.0 1.2e-21 77.2 16.8 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Kinetochor_Ybp2 PF08568.10 KIK38953.1 - 5.5e-14 51.6 2.2 7.1e-12 44.6 0.2 2.1 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin Transp_cyt_pur PF02133.15 KIK38954.1 - 3.9e-38 131.4 37.0 1.3e-37 129.7 37.0 1.7 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ibs_toxin PF13956.6 KIK38954.1 - 0.29 11.2 4.4 1.7 8.7 4.4 2.5 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Mob1_phocein PF03637.17 KIK38955.1 - 7.8e-25 87.8 0.0 1.4e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 Mob1/phocein family CENP-T_C PF15511.6 KIK38956.1 - 1.4e-06 28.3 0.0 1.5e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KIK38956.1 - 9.1e-05 22.8 0.0 0.00012 22.4 0.0 1.2 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KIK38956.1 - 0.0027 17.8 0.0 0.0027 17.8 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KIK38956.1 - 0.031 14.5 0.0 0.035 14.4 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4893 PF16233.5 KIK38956.1 - 0.12 12.0 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4893) Amidase PF01425.21 KIK38959.1 - 1.1e-91 308.1 0.0 1.5e-91 307.6 0.0 1.2 1 0 0 1 1 1 1 Amidase Thioredoxin PF00085.20 KIK38960.1 - 3.1e-21 75.3 0.0 3.5e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KIK38960.1 - 1.7e-09 38.1 0.0 5.7e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KIK38960.1 - 4.5e-07 29.7 0.0 5.2e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KIK38960.1 - 1.9e-05 24.9 0.0 0.0018 18.5 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 KIK38960.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KIK38960.1 - 0.0013 18.9 0.0 0.0021 18.2 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like DUF953 PF06110.11 KIK38960.1 - 0.0013 18.3 0.0 0.0028 17.3 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Redoxin PF08534.10 KIK38960.1 - 0.0027 17.4 0.1 0.0046 16.7 0.1 1.3 1 1 0 1 1 1 1 Redoxin Glutaredoxin PF00462.24 KIK38960.1 - 0.011 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin OST3_OST6 PF04756.13 KIK38960.1 - 0.021 14.2 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF2150 PF09920.9 KIK38962.1 - 0.037 14.0 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) RVT_thumb PF06817.14 KIK38964.1 - 0.028 14.3 0.0 0.088 12.7 0.1 1.8 2 0 0 2 2 2 0 Reverse transcriptase thumb domain Phage_int_SAM_4 PF13495.6 KIK38965.1 - 0.021 15.3 0.0 0.044 14.3 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain LUC7 PF03194.15 KIK38968.1 - 0.032 13.9 5.0 0.038 13.7 5.0 1.0 1 0 0 1 1 1 0 LUC7 N_terminus Vfa1 PF08432.10 KIK38968.1 - 0.3 11.4 6.5 0.38 11.1 6.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TMPIT PF07851.13 KIK38968.1 - 1.9 7.6 4.1 2.1 7.5 4.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein Isochorismatase PF00857.20 KIK38969.1 - 4e-10 40.2 0.0 1.3e-09 38.5 0.0 1.8 1 1 0 1 1 1 1 Isochorismatase family RasGEF PF00617.19 KIK38970.1 - 3.5e-12 46.9 0.0 5e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 RasGEF domain TRAPPC-Trs85 PF12739.7 KIK38971.1 - 0.06 12.3 0.0 0.33 9.9 0.0 1.9 2 0 0 2 2 2 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Ge1_WD40 PF16529.5 KIK38973.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1658 PF07871.11 KIK38973.1 - 1.5 8.9 6.5 1.5 8.9 0.9 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1658) Mucin PF01456.17 KIK38973.1 - 2.1 8.3 15.1 0.081 12.9 5.4 2.5 1 1 1 2 2 2 0 Mucin-like glycoprotein Baculo_PEP_C PF04513.12 KIK38974.1 - 1.3e-06 28.5 9.9 0.00036 20.6 9.6 2.2 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 KIK38974.1 - 0.00015 21.7 3.9 0.00022 21.2 3.9 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 KIK38974.1 - 0.0017 18.4 7.9 0.02 14.9 4.4 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) Spc7 PF08317.11 KIK38974.1 - 0.014 14.3 3.1 0.019 13.8 3.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein KASH_CCD PF14662.6 KIK38974.1 - 0.026 14.4 5.0 0.04 13.7 5.0 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Filament PF00038.21 KIK38974.1 - 0.029 14.0 2.8 0.038 13.6 2.8 1.2 1 0 0 1 1 1 0 Intermediate filament protein NPV_P10 PF05531.12 KIK38974.1 - 0.04 14.4 17.1 0.11 13.0 3.0 4.1 1 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DNA_pol_A_exo1 PF01612.20 KIK38974.1 - 0.042 13.5 0.4 0.081 12.6 0.4 1.5 1 0 0 1 1 1 0 3'-5' exonuclease Nup54_C PF18437.1 KIK38974.1 - 0.048 13.6 0.6 0.16 11.9 0.1 2.1 2 0 0 2 2 1 0 Nup54 C-terminal interacting domain FH2 PF02181.23 KIK38974.1 - 0.078 12.1 2.7 0.17 11.0 0.3 2.0 1 1 0 2 2 2 0 Formin Homology 2 Domain Laminin_II PF06009.12 KIK38974.1 - 0.091 12.8 9.5 0.47 10.5 0.9 3.0 1 1 1 2 2 2 0 Laminin Domain II AAA_32 PF13654.6 KIK38974.1 - 0.11 11.3 1.3 7.6 5.2 0.1 2.0 1 1 1 2 2 2 0 AAA domain ACCA PF03255.14 KIK38974.1 - 0.13 12.1 0.5 2.6 7.9 0.0 2.3 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Syntaxin PF00804.25 KIK38974.1 - 0.17 11.5 4.3 0.81 9.3 0.6 2.1 1 1 1 2 2 2 0 Syntaxin Bacillus_HBL PF05791.11 KIK38974.1 - 0.21 11.4 11.5 0.95 9.3 6.4 2.6 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) CENP-F_leu_zip PF10473.9 KIK38974.1 - 0.24 11.4 5.2 1.7 8.6 5.2 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TACC_C PF05010.14 KIK38974.1 - 0.24 11.2 2.2 4.1 7.2 0.2 2.3 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF2968 PF11180.8 KIK38974.1 - 0.25 10.9 5.3 1.7 8.2 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) WEMBL PF05701.11 KIK38974.1 - 0.28 9.9 1.9 0.33 9.6 0.5 1.5 1 1 0 1 1 1 0 Weak chloroplast movement under blue light BRE1 PF08647.11 KIK38974.1 - 0.3 11.2 2.1 0.55 10.3 0.7 2.1 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase EzrA PF06160.12 KIK38974.1 - 0.43 8.7 3.8 1.1 7.3 3.1 1.7 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA ApoLp-III PF07464.11 KIK38974.1 - 0.45 10.6 4.2 1 9.4 2.7 2.1 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Prominin PF05478.11 KIK38974.1 - 0.48 8.3 5.3 0.6 8.0 5.3 1.1 1 0 0 1 1 1 0 Prominin DUF5082 PF16888.5 KIK38974.1 - 0.54 10.5 6.3 1.5 9.1 3.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Lectin_N PF03954.14 KIK38974.1 - 0.62 9.8 6.7 1.3 8.8 6.2 1.8 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Baculo_p24 PF05073.12 KIK38974.1 - 0.62 9.8 6.8 0.67 9.7 3.0 2.4 1 1 1 2 2 2 0 Baculovirus P24 capsid protein PI3K_P85_iSH2 PF16454.5 KIK38974.1 - 0.7 9.5 5.0 1.1 8.8 0.4 2.6 1 1 3 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FAM184 PF15665.5 KIK38974.1 - 0.8 9.4 4.4 1.2 8.9 2.0 2.2 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B DUF1640 PF07798.11 KIK38974.1 - 1.3 9.1 7.3 75 3.3 7.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Zwint PF15556.6 KIK38974.1 - 1.4 8.3 6.9 25 4.2 5.8 2.6 1 1 1 2 2 2 0 ZW10 interactor Syntaxin_2 PF14523.6 KIK38974.1 - 1.5 9.3 11.1 0.41 11.0 4.7 2.4 2 1 1 3 3 2 0 Syntaxin-like protein COG2 PF06148.11 KIK38974.1 - 1.5 8.9 6.6 4 7.5 5.3 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 LPP PF04728.13 KIK38974.1 - 3.9 7.9 9.6 19 5.7 3.4 3.5 1 1 2 3 3 3 0 Lipoprotein leucine-zipper TolA_bind_tri PF16331.5 KIK38974.1 - 5.8 7.1 9.8 5.7 7.1 0.4 2.6 2 0 0 2 2 2 0 TolA binding protein trimerisation XRN_N PF03159.18 KIK38975.1 - 8.2e-53 179.3 0.0 9.9e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus WD40 PF00400.32 KIK38977.1 - 1.7e-05 25.4 0.2 0.00034 21.3 0.0 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat NMO PF03060.15 KIK38978.1 - 5.3e-53 180.5 0.4 4.1e-52 177.6 0.4 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KIK38978.1 - 1e-09 37.9 0.2 9.3e-05 21.6 0.3 2.3 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.17 KIK38978.1 - 0.00073 18.9 0.1 0.0015 17.9 0.1 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase FMN_dh PF01070.18 KIK38978.1 - 0.0017 17.5 0.5 0.0027 16.8 0.5 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.14 KIK38978.1 - 0.0059 15.8 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 KIK38978.1 - 0.074 12.5 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein ATPgrasp_N PF18130.1 KIK38978.1 - 0.15 12.7 0.3 80 3.9 0.0 3.5 4 0 0 4 4 4 0 ATP-grasp N-terminal domain RasGEF_N PF00618.20 KIK38979.1 - 2e-15 56.9 0.6 6.4e-15 55.3 0.2 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif RasGEF PF00617.19 KIK38979.1 - 5.5e-14 52.8 0.0 4.9e-13 49.7 0.0 2.5 2 0 0 2 2 2 1 RasGEF domain G-alpha PF00503.20 KIK38979.1 - 0.071 12.3 0.8 0.25 10.5 0.8 1.9 1 1 0 1 1 1 0 G-protein alpha subunit Ribosomal_L22 PF00237.19 KIK38980.1 - 1.4e-34 118.4 0.0 2.3e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e HECT PF00632.25 KIK38982.1 - 5.8e-96 321.6 0.0 7.4e-96 321.2 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KIK38982.1 - 3.8e-35 119.7 11.2 1.8e-12 47.1 0.3 4.1 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KIK38982.1 - 4.6e-16 59.0 0.0 9.7e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain ParBc_2 PF08857.11 KIK38982.1 - 0.0094 16.1 0.0 0.062 13.4 0.0 2.2 3 0 0 3 3 3 1 Putative ParB-like nuclease DUF908 PF06012.12 KIK38982.1 - 0.3 10.5 3.0 0.46 9.9 3.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Nas2_N PF18265.1 KIK38984.1 - 9.2e-30 102.4 0.3 1.4e-29 101.9 0.3 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain GRASP55_65 PF04495.14 KIK38984.1 - 1.4e-07 31.9 0.0 2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KIK38984.1 - 1.5e-06 27.9 0.4 5.9e-06 26.0 0.1 2.2 2 1 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KIK38984.1 - 0.00064 20.0 0.0 0.0018 18.6 0.0 1.8 2 0 0 2 2 2 1 PDZ domain NleF_casp_inhib PF16809.5 KIK38984.1 - 0.065 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 NleF caspase inhibitor DUF3627 PF12299.8 KIK38984.1 - 0.14 12.3 0.1 0.25 11.4 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3627) ETAA1 PF15350.6 KIK38984.1 - 0.22 9.8 0.0 0.31 9.3 0.0 1.1 1 0 0 1 1 1 0 Ewing's tumour-associated antigen 1 homologue CM_2 PF01817.21 KIK38986.1 - 6e-06 26.5 0.6 0.036 14.4 0.0 2.7 3 0 0 3 3 3 2 Chorismate mutase type II AstE_AspA PF04952.14 KIK38987.1 - 0.028 13.5 0.1 0.033 13.3 0.1 1.1 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Septin PF00735.18 KIK38988.1 - 8.1e-48 163.1 0.0 1.4e-18 67.2 0.0 3.6 4 0 0 4 4 4 3 Septin MMR_HSR1 PF01926.23 KIK38988.1 - 0.00027 21.0 0.0 0.00062 19.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIK38988.1 - 0.0017 17.9 0.0 0.0041 16.7 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KIK38988.1 - 0.0075 16.7 0.1 0.022 15.1 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIK38988.1 - 0.011 16.0 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KIK38988.1 - 0.031 13.6 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF815 PF05673.13 KIK38988.1 - 0.036 13.2 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Pox_A32 PF04665.12 KIK38988.1 - 0.075 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein 2C_adapt PF08793.10 KIK38988.1 - 0.12 12.6 0.6 0.29 11.3 0.6 1.6 1 0 0 1 1 1 0 2-cysteine adaptor domain AAA_28 PF13521.6 KIK38988.1 - 0.13 12.5 0.2 4 7.6 0.2 3.0 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KIK38989.1 - 5.3e-33 114.5 0.2 2.2e-10 40.3 0.1 3.2 3 0 0 3 3 3 3 Septin Zn_clus PF00172.18 KIK38989.1 - 1e-19 70.3 27.2 2.7e-10 40.2 8.9 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain ILVD_EDD PF00920.21 KIK38992.1 - 1.2e-205 684.0 1.2 1.4e-205 683.8 1.2 1.1 1 0 0 1 1 1 1 Dehydratase family RIO1 PF01163.22 KIK38993.1 - 1.1e-70 237.1 0.4 1.9e-70 236.3 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KIK38993.1 - 0.00031 20.8 1.3 0.47 10.3 0.4 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KIK38993.1 - 0.00081 18.8 0.2 0.016 14.5 0.2 2.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK38993.1 - 0.09 11.5 0.1 0.09 11.5 0.1 2.1 3 0 0 3 3 3 0 Fungal protein kinase Pes-10 PF07149.11 KIK38993.1 - 7.2 5.6 9.0 3.2 6.7 6.2 1.8 2 0 0 2 2 2 0 Pes-10 DUF2208 PF09973.9 KIK38994.1 - 0.031 13.9 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) F-box PF00646.33 KIK38995.1 - 2.2e-05 24.2 0.4 6.4e-05 22.7 0.4 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK38995.1 - 0.0023 17.8 0.5 0.0023 17.8 0.5 1.9 2 0 0 2 2 2 1 F-box-like DUF4504 PF14953.6 KIK38997.1 - 3.6e-07 29.8 0.1 3.9e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4504) Pro_isomerase PF00160.21 KIK38998.1 - 2.8e-49 167.4 0.1 4.8e-49 166.7 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KIK38998.1 - 5.3e-09 36.6 0.1 0.00069 20.4 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Eaf7 PF07904.13 KIK38999.1 - 7.4e-18 64.9 0.0 1.4e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 F-box-like PF12937.7 KIK39000.1 - 0.00033 20.5 0.6 0.0016 18.3 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK39000.1 - 0.063 13.2 0.1 0.19 11.7 0.1 1.8 1 0 0 1 1 1 0 F-box domain zf-C2H2_12 PF18658.1 KIK39000.1 - 0.13 11.9 0.9 0.34 10.5 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger C2H2-type zf-RING_UBOX PF13445.6 KIK39002.1 - 8e-05 22.6 6.8 8e-05 22.6 6.8 2.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIK39002.1 - 0.00098 19.4 6.9 0.00098 19.4 6.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK39002.1 - 0.0011 18.8 5.9 0.0011 18.8 5.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK39002.1 - 0.0022 17.8 13.1 0.016 15.1 4.4 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK39002.1 - 0.0026 17.6 5.7 0.0026 17.6 5.7 2.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KIK39002.1 - 0.0086 16.2 3.0 0.0086 16.2 3.0 2.0 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KIK39002.1 - 0.0095 16.1 5.0 0.0095 16.1 5.0 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KIK39002.1 - 0.016 15.1 2.0 0.03 14.2 2.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein YscO-like PF16789.5 KIK39002.1 - 0.016 15.2 4.9 0.025 14.6 4.9 1.2 1 0 0 1 1 1 0 YscO-like protein CIAPIN1 PF05093.13 KIK39002.1 - 0.019 15.4 1.1 0.019 15.4 1.1 1.8 1 1 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF3584 PF12128.8 KIK39002.1 - 0.022 12.3 4.3 0.028 11.9 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Uso1_p115_C PF04871.13 KIK39002.1 - 0.038 14.3 6.1 0.067 13.6 6.1 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HAUS5 PF14817.6 KIK39002.1 - 0.043 12.6 4.3 0.056 12.2 4.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 ExsD PF16806.5 KIK39002.1 - 0.054 13.4 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Antiactivator protein ExsD zf-RING_5 PF14634.6 KIK39002.1 - 0.12 12.3 15.2 0.069 13.1 5.9 2.4 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KIK39002.1 - 0.21 11.5 12.6 2.2 8.2 5.8 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Spc7 PF08317.11 KIK39002.1 - 0.53 9.1 6.2 0.74 8.6 6.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein SlyX PF04102.12 KIK39002.1 - 0.67 10.6 9.0 2.4 8.9 6.8 2.3 1 1 1 2 2 2 0 SlyX HIP1_clath_bdg PF16515.5 KIK39002.1 - 1 10.0 8.3 1.9 9.1 8.3 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 OmpH PF03938.14 KIK39002.1 - 2.2 8.6 7.9 4.1 7.8 7.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF349 PF03993.12 KIK39002.1 - 6 7.2 8.3 4 7.8 6.5 1.6 2 0 0 2 2 1 0 Domain of Unknown Function (DUF349) Leader_Thr PF08254.11 KIK39004.1 - 0.042 13.6 1.5 0.071 12.9 1.5 1.4 1 0 0 1 1 1 0 Threonine leader peptide DUF1902 PF08972.11 KIK39004.1 - 0.12 12.4 0.0 0.64 10.0 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1902) Caps_synth PF05704.12 KIK39004.1 - 0.17 11.3 0.0 0.18 11.2 0.0 1.0 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein RicinB_lectin_2 PF14200.6 KIK39005.1 - 1.7e-14 54.3 1.6 5.5e-09 36.6 0.7 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIK39005.1 - 5.9e-07 29.8 0.1 0.008 16.4 0.1 2.2 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain Peptidase_S9 PF00326.21 KIK39006.1 - 1.6e-29 102.9 0.0 2.3e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KIK39006.1 - 2e-06 27.2 0.2 0.0013 18.1 0.1 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK39006.1 - 3.6e-05 23.5 0.0 0.0022 17.7 0.2 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S28 PF05577.12 KIK39006.1 - 0.024 13.4 0.0 0.037 12.8 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DUF2920 PF11144.8 KIK39006.1 - 0.05 12.8 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) FSH1 PF03959.13 KIK39006.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.18 KIK39006.1 - 0.12 11.9 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family SET PF00856.28 KIK39010.1 - 0.00037 20.9 0.0 0.00065 20.1 0.0 1.4 1 0 0 1 1 1 1 SET domain Peptidase_M28 PF04389.17 KIK39011.1 - 1.4e-26 93.4 0.0 2.2e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIK39011.1 - 5.6e-05 22.9 0.0 8.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KIK39011.1 - 0.0095 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Nicastrin Acetyltransf_1 PF00583.25 KIK39012.1 - 8.7e-16 58.2 0.0 1.2e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KIK39012.1 - 1.5e-08 34.5 0.0 2.3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KIK39012.1 - 1.9e-08 34.3 0.0 2.7e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK39012.1 - 3.4e-08 33.8 0.0 4.8e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIK39012.1 - 1.3e-05 25.9 0.0 1.8e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIK39012.1 - 0.00049 19.8 0.0 0.00079 19.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIK39012.1 - 0.0023 18.0 0.0 0.0039 17.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIK39012.1 - 0.012 15.7 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIK39012.1 - 0.03 14.5 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PanZ PF12568.8 KIK39012.1 - 0.11 12.2 0.1 0.36 10.6 0.1 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Nup192 PF11894.8 KIK39013.1 - 8.6e-246 818.8 0.0 1e-245 818.5 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 STAS_2 PF13466.6 KIK39013.1 - 0.065 13.6 1.1 0.3 11.5 1.1 2.2 1 0 0 1 1 1 0 STAS domain Got1 PF04178.12 KIK39014.1 - 5.1e-32 110.6 12.2 6.8e-32 110.2 12.2 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family AgrB PF04647.15 KIK39014.1 - 0.0017 17.7 4.5 0.0022 17.3 4.5 1.1 1 0 0 1 1 1 1 Accessory gene regulator B MNHE PF01899.16 KIK39014.1 - 2.1 8.1 7.5 0.24 11.1 1.5 1.9 1 1 1 2 2 2 0 Na+/H+ ion antiporter subunit WD40 PF00400.32 KIK39015.1 - 2.5e-51 170.5 28.7 2.9e-08 34.2 0.8 7.4 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39015.1 - 1.5e-22 79.7 4.9 7.4e-05 23.0 0.0 5.8 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK39015.1 - 1.6e-09 37.2 0.8 0.11 11.5 0.0 5.5 1 1 4 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK39015.1 - 1.3e-06 27.4 6.6 0.057 12.1 0.0 4.4 2 2 1 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK39015.1 - 5.2e-06 26.5 0.0 0.65 9.8 0.0 3.2 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK39015.1 - 1.2e-05 25.1 0.1 4 7.5 0.0 4.8 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK39015.1 - 2.3e-05 23.9 0.0 0.055 12.8 0.0 3.1 2 1 1 3 3 3 2 WD40-like domain Nbas_N PF15492.6 KIK39015.1 - 4.5e-05 22.9 0.6 0.046 13.1 0.1 3.3 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Ceramidase_alk PF04734.13 KIK39015.1 - 0.079 11.6 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, N-terminal Frtz PF11768.8 KIK39015.1 - 0.092 11.0 0.0 0.98 7.6 0.0 2.4 2 1 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz TonB_2 PF13103.6 KIK39015.1 - 0.14 12.5 0.2 4.4 7.6 0.0 2.8 3 0 0 3 3 3 0 TonB C terminal WD40 PF00400.32 KIK39017.1 - 3.5e-47 157.4 27.6 3.7e-09 37.1 0.9 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39017.1 - 7.9e-21 74.2 2.8 0.0019 18.5 0.0 5.9 1 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK39017.1 - 2.1e-09 36.6 2.9 0.0084 14.8 0.3 4.4 2 2 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK39017.1 - 2.8e-08 33.1 1.3 1.1 8.1 0.0 6.1 1 1 4 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK39017.1 - 5.9e-05 22.5 0.0 1.2 8.4 0.0 3.4 1 1 2 4 4 4 3 WD40-like domain Nucleoporin_N PF08801.11 KIK39017.1 - 0.0013 17.5 2.1 0.21 10.3 0.1 3.7 2 2 2 4 4 4 2 Nup133 N terminal like Nbas_N PF15492.6 KIK39017.1 - 0.0018 17.7 0.2 0.39 10.0 0.1 3.4 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 KIK39017.1 - 0.081 11.2 0.0 0.88 7.8 0.0 2.0 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 KIK39017.1 - 0.17 10.4 1.3 13 4.2 0.1 2.9 1 1 2 3 3 3 0 Cytochrome D1 heme domain PALB2_WD40 PF16756.5 KIK39017.1 - 1.1 8.1 7.8 5 5.9 0.3 3.3 2 2 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain WD40 PF00400.32 KIK39018.1 - 1.4e-41 139.6 32.1 1.3e-06 29.0 1.5 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39018.1 - 3.1e-14 53.0 3.7 0.0072 16.6 0.1 5.6 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK39018.1 - 1.2e-06 27.5 3.4 0.0018 17.0 0.2 3.9 3 2 1 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK39018.1 - 2.3e-06 26.8 0.1 0.52 9.2 0.0 5.5 2 2 4 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK39018.1 - 0.00031 20.6 0.0 26 4.9 0.0 4.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK39018.1 - 0.0081 15.5 0.1 0.55 9.5 0.1 3.1 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 KIK39018.1 - 0.033 12.5 0.0 0.74 8.0 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 KIK39019.1 - 1.5e-46 155.4 37.0 8.5e-09 35.9 0.8 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39019.1 - 2.1e-19 69.6 2.8 0.001 19.3 0.1 5.5 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK39019.1 - 3e-08 32.8 4.3 0.0011 17.8 0.3 4.1 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK39019.1 - 1.2e-06 27.7 1.2 0.55 9.1 0.0 5.1 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK39019.1 - 2.9e-06 26.8 0.0 0.00022 20.6 0.0 2.9 3 1 0 3 3 3 1 WD40-like domain Cytochrom_D1 PF02239.16 KIK39019.1 - 0.0021 16.7 1.2 0.031 12.8 0.2 2.5 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nbas_N PF15492.6 KIK39019.1 - 0.0057 16.0 0.5 1.2 8.4 0.1 3.5 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KIK39019.1 - 0.0089 15.9 0.0 21 5.2 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 KIK39019.1 - 0.021 13.6 1.9 4.4 5.9 0.2 3.6 2 2 2 4 4 4 0 Nup133 N terminal like PQQ PF01011.21 KIK39019.1 - 0.069 13.1 0.0 3.4 7.7 0.0 3.7 3 0 0 3 3 3 0 PQQ enzyme repeat PALB2_WD40 PF16756.5 KIK39019.1 - 0.7 8.8 6.3 9.3 5.1 0.1 3.1 3 1 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Amidohydro_2 PF04909.14 KIK39020.1 - 6.7e-19 68.8 0.5 1.4e-18 67.7 0.0 1.8 3 0 0 3 3 3 1 Amidohydrolase TatD_DNase PF01026.21 KIK39020.1 - 9.3e-05 21.9 0.3 0.00015 21.3 0.0 1.5 2 0 0 2 2 2 1 TatD related DNase HSP20 PF00011.21 KIK39023.1 - 0.00016 21.7 0.1 0.00018 21.6 0.1 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.16 KIK39023.1 - 0.05 14.6 0.0 0.051 14.6 0.0 1.1 1 0 0 1 1 1 0 CS domain ArsA_HSP20 PF17886.1 KIK39023.1 - 0.095 12.3 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 HSP20-like domain found in ArsA FixH PF05751.11 KIK39024.1 - 0.074 13.1 0.4 0.15 12.0 0.4 1.5 1 0 0 1 1 1 0 FixH Pkinase_fungal PF17667.1 KIK39025.1 - 1.1e-14 54.1 0.0 1.3e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK39025.1 - 0.041 13.3 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Peptidase_M36 PF02128.15 KIK39027.1 - 9e-145 482.5 4.6 1.1e-144 482.2 4.6 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KIK39027.1 - 5e-10 39.1 5.3 1.1e-09 37.9 5.3 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Trypan_PARP PF05887.11 KIK39027.1 - 0.088 12.8 0.6 0.25 11.3 0.6 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) F-box PF00646.33 KIK39028.1 - 0.025 14.5 0.1 0.079 12.9 0.1 1.9 1 0 0 1 1 1 0 F-box domain zf-C2H2_aberr PF17017.5 KIK39029.1 - 0.00049 20.3 4.2 0.5 10.5 0.0 2.9 3 0 0 3 3 3 2 Aberrant zinc-finger zf-C2H2 PF00096.26 KIK39029.1 - 0.002 18.5 8.2 0.032 14.7 1.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK39029.1 - 0.4 11.6 14.1 1.4 10.0 0.7 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger Abhydrolase_3 PF07859.13 KIK39031.1 - 6.3e-10 39.3 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIK39031.1 - 3.5e-07 29.5 0.0 2.2e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase PF07224.11 KIK39031.1 - 7.1e-05 22.0 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 KIK39031.1 - 7.9e-05 21.7 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme RhoGEF PF00621.20 KIK39033.1 - 4.5e-23 82.4 0.0 9.8e-23 81.3 0.0 1.6 2 0 0 2 2 2 1 RhoGEF domain Sulfate_transp PF00916.20 KIK39034.1 - 5.2e-55 186.7 20.7 2.2e-27 95.8 0.3 2.3 2 0 0 2 2 2 2 Sulfate permease family cNMP_binding PF00027.29 KIK39034.1 - 1e-10 41.5 0.0 2.1e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KIK39034.1 - 2.1e-10 40.3 0.1 4e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KIK39034.1 - 0.0051 17.1 0.2 0.011 16.0 0.2 1.6 1 0 0 1 1 1 1 STAS domain HET PF06985.11 KIK39036.1 - 2.8e-12 47.2 2.1 4.4e-09 36.8 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.11 KIK39037.1 - 8.4e-08 32.7 0.2 3.6e-06 27.4 0.0 2.3 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) TED_complement PF07678.14 KIK39037.1 - 0.21 10.6 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 A-macroglobulin TED domain NUDIX_2 PF13869.6 KIK39039.1 - 1.6e-84 282.2 0.0 1.8e-84 282.0 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Ras PF00071.22 KIK39040.1 - 5.6e-56 188.6 0.0 6.7e-56 188.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK39040.1 - 9.2e-32 109.8 0.0 1.3e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK39040.1 - 5.7e-15 55.2 0.0 7.1e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIK39040.1 - 5.1e-06 26.0 0.0 6.1e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIK39040.1 - 6.6e-06 26.2 0.0 9.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIK39040.1 - 0.00012 21.7 0.1 0.00033 20.3 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KIK39040.1 - 0.0033 17.2 0.0 0.016 15.0 0.0 1.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KIK39040.1 - 0.044 13.2 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KIK39040.1 - 0.044 14.1 0.0 0.077 13.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 KIK39040.1 - 0.069 12.3 0.5 2 7.5 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit RsgA_GTPase PF03193.16 KIK39040.1 - 0.073 13.0 0.1 3.4 7.5 0.0 2.3 1 1 1 3 3 3 0 RsgA GTPase Septin PF00735.18 KIK39040.1 - 0.17 11.1 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Septin MMR_HSR1 PF01926.23 KIK39043.1 - 2.4e-10 40.5 0.0 3.3e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KIK39043.1 - 5.2e-06 26.7 0.0 1e-05 25.8 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KIK39043.1 - 5.3e-06 26.4 0.0 1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Ras PF00071.22 KIK39043.1 - 6.7e-06 25.8 0.0 1.4e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Ras family IIGP PF05049.13 KIK39043.1 - 0.0021 17.2 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 KIK39043.1 - 0.0049 17.4 0.2 0.0075 16.8 0.2 1.4 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KIK39043.1 - 0.0072 16.7 0.2 0.018 15.4 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AIG1 PF04548.16 KIK39043.1 - 0.0078 15.6 0.0 0.0093 15.3 0.0 1.2 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.18 KIK39043.1 - 0.011 15.2 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.6 KIK39043.1 - 0.015 15.1 0.2 0.029 14.1 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 KIK39043.1 - 0.018 14.3 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 KIK39043.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 KIK39043.1 - 0.065 12.8 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain RNA_helicase PF00910.22 KIK39043.1 - 0.096 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 KIK39043.1 - 0.13 12.5 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KIK39043.1 - 0.14 11.3 0.2 0.3 10.2 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Dynamin_N PF00350.23 KIK39043.1 - 0.15 12.1 0.1 0.23 11.5 0.1 1.4 1 1 0 1 1 1 0 Dynamin family DUF202 PF02656.15 KIK39044.1 - 1.8e-12 47.5 5.9 1.8e-12 47.5 5.9 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DEAD PF00270.29 KIK39045.1 - 1.3e-34 119.5 0.1 2.2e-34 118.7 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK39045.1 - 1.3e-26 93.1 1.9 1.7e-26 92.8 0.4 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KIK39045.1 - 0.0079 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK39045.1 - 0.011 16.0 1.4 0.11 12.8 0.6 2.6 2 1 0 2 2 2 0 AAA domain DUF1729 PF08354.10 KIK39047.1 - 3.6e-150 499.8 0.0 6.8e-150 498.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) FAS_I_H PF18314.1 KIK39047.1 - 1.3e-72 243.7 0.2 2.7e-72 242.7 0.2 1.6 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 KIK39047.1 - 4.4e-72 241.7 0.0 1.4e-71 240.1 0.0 2.0 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain Acyl_transf_1 PF00698.21 KIK39047.1 - 1.5e-71 241.5 0.1 7.4e-70 236.0 0.0 3.2 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 KIK39047.1 - 1.4e-45 154.7 0.0 5.2e-45 152.8 0.0 2.1 2 0 0 2 2 2 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 KIK39047.1 - 1.1e-29 103.9 0.0 2.4e-29 102.8 0.0 1.7 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 KIK39047.1 - 6.5e-29 100.0 0.0 2.8e-28 97.9 0.0 2.2 1 0 0 1 1 1 1 MaoC like domain ketoacyl-synt PF00109.26 KIK39047.1 - 1.7e-24 86.8 0.1 4.7e-24 85.3 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain FAS_N PF17828.1 KIK39047.1 - 3.3e-19 69.2 0.2 6.7e-19 68.2 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Ketoacyl-synt_C PF02801.22 KIK39047.1 - 8.6e-16 58.0 0.1 2.2e-15 56.7 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 KIK39047.1 - 5.1e-14 52.4 0.0 1.4e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily MaoC_dehydrat_N PF13452.6 KIK39047.1 - 3.6e-12 46.6 0.1 1.1e-11 45.0 0.0 1.9 2 0 0 2 2 1 1 N-terminal half of MaoC dehydratase adh_short PF00106.25 KIK39047.1 - 9e-06 25.3 0.0 4.8e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KIK39047.1 - 0.068 13.1 0.1 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 KR domain DUF4061 PF13270.6 KIK39047.1 - 0.22 11.8 1.8 0.35 11.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) Glyco_hydro_17 PF00332.18 KIK39049.1 - 1.1e-07 31.7 4.6 3.9e-07 30.0 1.2 2.4 1 1 0 2 2 2 1 Glycosyl hydrolases family 17 ETRAMP PF09716.10 KIK39049.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) RhoGAP PF00620.27 KIK39050.1 - 2.8e-38 131.1 0.0 4.4e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Mltc_N PF11873.8 KIK39050.1 - 0.05 13.3 0.1 0.11 12.3 0.1 1.6 1 1 0 1 1 1 0 Membrane-bound lytic murein transglycosylase C, N-terminal domain GMC_oxred_N PF00732.19 KIK39051.1 - 7.3e-68 229.1 0.0 1.2e-67 228.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK39051.1 - 7.4e-38 130.3 0.2 1.3e-37 129.5 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK39051.1 - 8.4e-06 25.1 0.1 1.4e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KIK39051.1 - 4.6e-05 23.2 0.0 0.0015 18.2 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK39051.1 - 5.5e-05 23.3 0.5 0.00018 21.7 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIK39051.1 - 7.3e-05 22.1 0.0 0.00023 20.5 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KIK39051.1 - 0.00029 20.0 0.0 0.0027 16.9 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK39051.1 - 0.0027 17.0 0.0 0.0055 16.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK39051.1 - 0.079 13.5 0.0 0.49 11.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK39051.1 - 0.081 11.6 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 KIK39051.1 - 0.2 10.4 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.7 KIK39051.1 - 0.28 10.5 0.6 7.7 5.7 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase KDZ PF18758.1 KIK39052.1 - 7.2e-49 166.4 0.0 1.4e-48 165.5 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Peptidase_C48 PF02902.19 KIK39052.1 - 1.3e-10 41.5 0.4 2.5e-10 40.6 0.4 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CxC1 PF18802.1 KIK39052.1 - 2e-05 24.7 0.9 4.6e-05 23.5 0.9 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Med3 PF11593.8 KIK39052.1 - 0.18 10.9 1.3 0.28 10.3 1.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CxC2 PF18803.1 KIK39052.1 - 0.47 10.6 2.8 1.1 9.5 2.8 1.5 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases Ribosomal_L20 PF00453.18 KIK39053.1 - 0.41 10.8 3.9 0.14 12.3 1.3 1.6 2 0 0 2 2 2 0 Ribosomal protein L20 RHD_dimer PF16179.5 KIK39056.1 - 0.0091 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Rel homology dimerisation domain SieB PF14163.6 KIK39057.1 - 0.054 13.0 0.0 0.066 12.7 0.0 1.1 1 0 0 1 1 1 0 Super-infection exclusion protein B DUF4536 PF15055.6 KIK39058.1 - 3.8e-05 23.8 5.9 8e-05 22.8 5.9 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) YrhK PF14145.6 KIK39058.1 - 0.15 12.0 2.3 1.7 8.6 0.5 2.1 1 1 0 1 1 1 0 YrhK-like protein p450 PF00067.22 KIK39059.1 - 4.5e-59 200.4 0.0 5.6e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Lipase_GDSL PF00657.22 KIK39060.1 - 3.2e-15 56.6 0.0 4.1e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KIK39060.1 - 1.4e-07 32.1 3.1 3.1e-07 30.9 3.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Peptidase_M1 PF01433.20 KIK39062.1 - 6.7e-36 123.9 0.0 8.8e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KIK39062.1 - 1.2e-29 102.6 0.0 2.3e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KIK39062.1 - 3.5e-17 63.2 0.0 6.9e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 KIK39062.1 - 0.47 10.9 3.1 11 6.5 3.1 2.4 1 1 0 1 1 1 0 M61 glycyl aminopeptidase HORMA PF02301.18 KIK39063.1 - 3.5e-15 56.2 0.1 6.2e-15 55.4 0.1 1.4 1 1 0 1 1 1 1 HORMA domain ATG101 PF07855.12 KIK39063.1 - 0.001 19.1 0.1 0.006 16.6 0.1 1.9 1 1 0 1 1 1 1 Autophagy-related protein 101 Hydrolase_4 PF12146.8 KIK39064.1 - 4.9e-14 52.2 0.0 5.3e-11 42.2 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK39064.1 - 6e-12 45.8 0.0 5.5e-11 42.6 0.0 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 KIK39064.1 - 1.2e-07 31.9 0.0 1.9e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 KIK39064.1 - 4e-07 30.9 0.0 1.1e-06 29.5 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 KIK39064.1 - 0.00069 19.2 0.0 0.076 12.5 0.0 2.5 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.12 KIK39064.1 - 0.0018 17.0 0.1 0.21 10.2 0.0 2.2 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 KIK39064.1 - 0.0018 18.1 0.0 3.1 7.5 0.0 3.1 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KIK39064.1 - 0.0051 16.3 0.0 0.062 12.8 0.0 2.5 1 1 1 2 2 2 1 Prolyl oligopeptidase family DUF1057 PF06342.12 KIK39064.1 - 0.029 13.4 0.0 0.041 12.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF1100 PF06500.11 KIK39064.1 - 0.032 13.0 0.0 0.045 12.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) LIDHydrolase PF10230.9 KIK39064.1 - 0.039 13.5 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.7 KIK39064.1 - 0.043 13.6 0.0 3 7.6 0.0 2.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family FSH1 PF03959.13 KIK39064.1 - 0.048 13.3 0.1 0.28 10.8 0.0 2.3 3 0 0 3 3 3 0 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 KIK39064.1 - 0.06 12.9 0.0 2.8 7.5 0.0 2.4 2 1 1 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 KIK39064.1 - 0.11 12.4 0.1 0.31 10.9 0.0 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF818 PF05677.12 KIK39064.1 - 0.17 10.8 0.1 0.25 10.2 0.1 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Baculo_PEP_C PF04513.12 KIK39065.1 - 0.0028 17.7 6.5 0.17 11.9 6.5 2.4 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus MMR_HSR1 PF01926.23 KIK39067.1 - 2.2e-07 31.0 0.0 4.3e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK39067.1 - 0.0008 19.4 0.0 0.0066 16.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KIK39067.1 - 0.053 12.8 0.3 0.15 11.3 0.1 1.9 2 0 0 2 2 2 0 AIG1 family Roc PF08477.13 KIK39067.1 - 0.055 13.7 0.0 0.22 11.8 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KIK39067.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 KIK39067.1 - 0.16 12.3 0.0 0.57 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KIK39067.1 - 0.17 12.4 0.0 0.4 11.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KIK39067.1 - 0.19 11.5 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Asp PF00026.23 KIK39068.1 - 1.1e-71 241.9 0.6 1.3e-71 241.6 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK39068.1 - 2e-06 28.1 0.5 0.00012 22.4 0.1 2.5 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK39068.1 - 0.0092 16.6 0.1 9.3 7.0 0.0 2.7 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KIK39068.1 - 0.026 15.1 0.2 10 6.8 0.0 2.8 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KIK39068.1 - 0.068 13.0 0.1 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal CHAT PF12770.7 KIK39069.1 - 3.8e-29 102.0 0.0 8.4e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK39069.1 - 5e-12 45.3 15.1 0.017 15.0 0.0 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIK39069.1 - 2.7e-05 24.4 16.7 1.4 9.3 0.2 8.0 4 3 4 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK39069.1 - 4.2e-05 23.2 1.9 6.4 6.8 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK39069.1 - 0.00026 20.9 0.0 36 4.9 0.0 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK39069.1 - 0.0036 16.9 0.0 16 5.3 0.0 4.9 5 0 0 5 5 5 0 TPR repeat TPR_2 PF07719.17 KIK39069.1 - 0.0053 16.8 7.9 2.4 8.5 0.1 6.5 8 0 0 8 8 6 1 Tetratricopeptide repeat MIT PF04212.18 KIK39069.1 - 0.01 15.9 3.8 15 5.8 0.1 5.3 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain Dehydratase_SU PF02287.15 KIK39069.1 - 0.011 15.9 2.3 1.1 9.3 0.0 3.0 3 0 0 3 3 3 0 Dehydratase small subunit TPR_7 PF13176.6 KIK39069.1 - 0.011 15.7 10.2 7.7 6.8 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat Scm3 PF10384.9 KIK39069.1 - 0.077 12.8 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 Centromere protein Scm3 Zeta_toxin PF06414.12 KIK39069.1 - 0.15 11.3 0.0 0.35 10.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin zf-C2H2_4 PF13894.6 KIK39073.1 - 0.0045 17.7 5.6 0.2 12.6 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK39073.1 - 0.0084 16.5 6.6 0.21 12.1 0.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KIK39073.1 - 0.3 10.9 3.3 5.2 6.9 1.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-TRAF PF02176.18 KIK39073.1 - 0.49 11.1 4.1 1.5 9.6 4.1 1.7 1 1 1 2 2 2 0 TRAF-type zinc finger Glyco_hydro_61 PF03443.14 KIK39075.1 - 5.7e-53 179.9 0.1 7.7e-53 179.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.16 KIK39077.1 - 4.4e-38 131.1 27.9 1.3e-37 129.6 28.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily 60KD_IMP PF02096.20 KIK39077.1 - 0.079 12.8 4.3 0.21 11.4 0.0 2.4 2 0 0 2 2 2 0 60Kd inner membrane protein PTCB-BRCT PF12738.7 KIK39078.1 - 3.2e-26 91.0 2.3 5e-14 52.0 0.0 5.6 5 0 0 5 5 5 2 twin BRCT domain BRCT PF00533.26 KIK39078.1 - 1.4e-25 89.4 0.0 9.7e-10 38.7 0.0 6.1 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KIK39078.1 - 4.6e-21 75.0 0.0 0.0041 17.5 0.0 7.4 7 0 0 7 7 7 5 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KIK39078.1 - 1.2e-18 66.8 0.0 1.8e-16 59.8 0.0 3.3 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KIK39078.1 - 0.0016 18.5 0.2 0.31 11.1 0.0 3.6 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain zf-CCHC PF00098.23 KIK39080.1 - 0.0038 17.2 3.9 0.0062 16.6 3.9 1.3 1 0 0 1 1 1 1 Zinc knuckle G-alpha PF00503.20 KIK39082.1 - 9.2e-107 357.3 0.0 1.1e-106 357.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK39082.1 - 3.5e-13 49.4 0.3 1.3e-08 34.4 0.0 2.6 3 0 0 3 3 3 2 ADP-ribosylation factor family Roc PF08477.13 KIK39082.1 - 0.0053 17.0 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KIK39082.1 - 0.0063 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 KIK39082.1 - 0.018 14.4 0.1 2.3 7.5 0.1 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 KIK39082.1 - 0.023 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family DAP3 PF10236.9 KIK39082.1 - 0.16 11.1 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 GTP_EFTU PF00009.27 KIK39082.1 - 0.2 11.2 0.0 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FmdA_AmdA PF03069.15 KIK39083.1 - 1.6e-58 198.4 0.1 6.2e-35 120.7 0.3 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family TRAM PF01938.20 KIK39083.1 - 0.013 15.4 0.0 1.9 8.6 0.0 2.7 2 0 0 2 2 2 0 TRAM domain MutL_C PF08676.11 KIK39084.1 - 1.9e-22 79.6 0.1 4.3e-22 78.5 0.1 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KIK39084.1 - 4.8e-20 71.4 0.0 9.5e-20 70.5 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KIK39084.1 - 1.1e-10 41.5 0.1 2.4e-10 40.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KIK39084.1 - 1.6e-06 28.6 0.1 9.6e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Vpu PF00558.19 KIK39085.1 - 0.032 14.0 0.0 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 Vpu protein Spectrin_like PF18373.1 KIK39086.1 - 7.3e-05 22.8 1.9 0.15 12.1 0.1 2.3 2 0 0 2 2 2 2 Spectrin like domain Phage_int_SAM_6 PF18644.1 KIK39086.1 - 0.042 13.9 0.2 0.12 12.4 0.2 1.8 2 1 0 2 2 2 0 Phage integrase SAM-like domain PNK3P PF08645.11 KIK39086.1 - 0.085 12.6 0.3 4.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase DUF1002 PF06207.11 KIK39086.1 - 0.16 11.5 1.5 0.22 11.0 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) Dynamin_N PF00350.23 KIK39087.1 - 5.2e-16 59.2 0.0 1.9e-14 54.0 0.0 2.7 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KIK39087.1 - 2.6e-10 40.4 0.5 7.1e-05 22.9 0.0 2.8 2 1 1 3 3 3 2 50S ribosome-binding GTPase AIG1 PF04548.16 KIK39087.1 - 8.9e-07 28.4 2.2 0.0019 17.5 0.0 2.3 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 KIK39087.1 - 4.8e-05 23.3 0.6 0.00043 20.2 0.0 2.5 2 1 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KIK39087.1 - 0.00022 21.7 0.2 0.003 18.1 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 KIK39087.1 - 0.0059 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KIK39087.1 - 0.0078 16.7 3.6 0.38 11.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIK39087.1 - 0.0087 16.5 0.1 0.19 12.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Ribosomal_L22e PF01776.17 KIK39087.1 - 0.028 14.8 0.8 0.58 10.6 0.0 2.4 2 0 0 2 2 2 0 Ribosomal L22e protein family Roc PF08477.13 KIK39087.1 - 0.038 14.2 0.1 2.3 8.4 0.0 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 KIK39087.1 - 0.11 12.5 1.8 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 KIK39087.1 - 0.18 12.1 0.9 1 9.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain DUF1548 PF07579.11 KIK39087.1 - 0.26 11.6 2.8 2.6 8.4 1.5 2.7 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1548) ABC_tran_CTD PF16326.5 KIK39087.1 - 0.55 10.5 4.0 0.97 9.7 1.7 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain CHAT PF12770.7 KIK39089.1 - 1.5e-09 37.7 0.0 1.7e-09 37.6 0.0 1.0 1 0 0 1 1 1 1 CHAT domain Peptidase_M20 PF01546.28 KIK39089.1 - 0.036 13.8 0.0 0.036 13.8 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 FSIP2 PF15783.5 KIK39089.1 - 0.12 10.2 0.0 0.13 10.2 0.0 1.0 1 0 0 1 1 1 0 Fibrous sheath-interacting protein 2 ATP-synt_DE PF00401.20 KIK39089.1 - 0.13 12.5 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain WD40 PF00400.32 KIK39092.1 - 3.6e-22 78.2 2.5 8.4e-09 35.9 0.0 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39092.1 - 2.8e-13 50.0 0.1 0.00012 22.3 0.0 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK39092.1 - 1.2e-07 31.0 0.0 0.00053 19.0 0.0 2.1 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK39092.1 - 1.7e-06 27.0 0.3 0.00036 19.3 0.0 2.2 1 1 0 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK39092.1 - 0.0018 17.7 0.0 0.01 15.2 0.0 1.8 1 1 1 2 2 2 1 WD40-like domain BBS2_Mid PF14783.6 KIK39092.1 - 0.0033 17.4 0.0 0.71 9.9 0.0 2.1 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region DUF2117 PF09890.9 KIK39092.1 - 0.01 15.3 0.0 0.97 8.9 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2117) Nucleoporin_N PF08801.11 KIK39092.1 - 0.011 14.5 0.1 0.048 12.4 0.0 1.8 1 1 1 2 2 2 0 Nup133 N terminal like PD40 PF07676.12 KIK39092.1 - 0.014 15.3 0.1 2.7 8.0 0.0 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KIK39092.1 - 0.018 13.6 0.0 0.019 13.5 0.0 1.1 1 0 0 1 1 1 0 Cytochrome D1 heme domain Nbas_N PF15492.6 KIK39092.1 - 0.019 14.3 0.0 2.2 7.5 0.0 2.0 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 KIK39092.1 - 0.03 12.7 0.0 3.8 5.7 0.0 2.0 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF5046 PF16465.5 KIK39092.1 - 0.036 13.5 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5046) WD40 PF00400.32 KIK39095.1 - 2.2e-52 173.9 16.5 7.4e-09 36.1 0.4 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39095.1 - 1.2e-23 83.2 0.3 0.011 16.1 0.0 6.9 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK39095.1 - 3.6e-10 39.3 0.1 0.39 9.6 0.0 5.7 1 1 5 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK39095.1 - 1.2e-06 28.5 0.0 0.078 12.8 0.0 3.1 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK39095.1 - 6.6e-05 22.7 3.5 17 5.5 0.0 6.9 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK39095.1 - 0.00088 18.0 7.3 3.3 6.2 0.0 4.8 3 2 3 6 6 6 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KIK39095.1 - 0.0057 16.7 0.0 0.2 11.7 0.0 2.4 1 1 1 2 2 2 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 KIK39095.1 - 0.011 15.1 0.0 15 4.8 0.0 3.3 2 1 1 4 4 4 0 WD40-like domain PAP_PilO PF06864.12 KIK39095.1 - 0.039 12.8 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Frtz PF11768.8 KIK39095.1 - 0.17 10.1 0.0 22 3.2 0.0 2.7 3 1 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz IKI3 PF04762.12 KIK39095.1 - 0.24 9.4 0.8 0.56 8.1 0.4 1.8 2 1 0 2 2 2 0 IKI3 family TFIIIC_delta PF12657.7 KIK39095.1 - 3.1 7.7 9.0 0.45 10.4 2.4 2.8 2 2 0 2 2 2 0 Transcription factor IIIC subunit delta N-term DUF3421 PF11901.8 KIK39097.1 - 6.1e-09 35.9 0.0 5.6e-06 26.3 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) CPSase_L_D2 PF02786.17 KIK39101.1 - 1.5e-116 387.3 0.2 4.5e-83 277.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain OTCace_N PF02729.21 KIK39101.1 - 1.1e-46 158.6 0.0 2.1e-46 157.6 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 KIK39101.1 - 1.7e-41 141.4 0.0 6.6e-41 139.5 0.0 2.1 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain GATase PF00117.28 KIK39101.1 - 1.2e-33 116.5 0.0 9.2e-32 110.4 0.0 2.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace PF00185.24 KIK39101.1 - 3.5e-30 105.2 0.0 1.1e-29 103.6 0.0 1.9 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 KIK39101.1 - 2.9e-19 69.1 0.0 1e-18 67.3 0.0 2.1 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 KIK39101.1 - 1.1e-17 64.3 0.1 9.4e-09 35.1 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KIK39101.1 - 7.9e-17 61.3 0.1 3.9e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KIK39101.1 - 3.6e-10 39.7 0.1 0.00013 21.8 0.0 2.8 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 KIK39101.1 - 1.1e-05 25.3 1.1 0.00097 19.0 0.1 2.9 2 1 0 2 2 2 1 Peptidase C26 ATP-grasp_3 PF02655.14 KIK39101.1 - 5.7e-05 23.2 0.1 0.21 11.6 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain RimK PF08443.11 KIK39101.1 - 0.0045 16.6 0.0 1.7 8.2 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 KIK39101.1 - 0.0078 15.7 0.0 0.37 10.2 0.1 2.5 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KIK39101.1 - 0.011 15.5 0.0 0.78 9.5 0.0 2.5 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.24 KIK39101.1 - 0.14 12.0 0.3 34 4.2 0.0 4.0 5 0 0 5 5 5 0 DJ-1/PfpI family SLATT_fungal PF18142.1 KIK39102.1 - 6.9e-41 139.0 0.1 8.9e-41 138.6 0.1 1.1 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Npa1 PF11707.8 KIK39102.1 - 0.036 13.4 0.0 0.045 13.1 0.0 1.1 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal PABP PF00658.18 KIK39102.1 - 0.057 13.6 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Poly-adenylate binding protein, unique domain CBFD_NFYB_HMF PF00808.23 KIK39103.1 - 3.3e-16 59.3 2.7 3.3e-16 59.3 2.7 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK39103.1 - 3.7e-06 27.3 0.6 3.7e-06 27.3 0.6 2.4 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 KIK39103.1 - 0.0044 17.1 2.0 0.011 15.9 2.0 1.5 1 0 0 1 1 1 1 hTAFII28-like protein conserved region DUF5427 PF10310.9 KIK39103.1 - 0.2 10.6 7.1 0.26 10.2 7.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SLD5_C PF16922.5 KIK39104.1 - 8.9e-11 41.8 0.0 1.4e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KIK39104.1 - 0.0001 22.8 0.1 0.00019 21.8 0.1 1.5 1 0 0 1 1 1 1 GINS complex protein Cyt-b5 PF00173.28 KIK39106.1 - 4e-12 46.1 0.0 5.3e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MFS_1 PF07690.16 KIK39109.1 - 1.7e-38 132.4 63.8 1.2e-36 126.4 63.8 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DnaJ-X PF14308.6 KIK39110.1 - 3.3e-55 186.8 0.7 3.3e-55 186.8 0.7 2.0 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KIK39110.1 - 1.3e-24 86.0 1.6 1.3e-24 86.0 1.6 2.3 2 0 0 2 2 2 1 DnaJ domain Mu-like_Pro PF10123.9 KIK39110.1 - 9.6 5.6 10.8 1e+02 2.3 10.8 2.4 1 1 0 1 1 1 0 Mu-like prophage I protein tRNA-synt_1b PF00579.25 KIK39111.1 - 9.2e-61 205.7 0.0 2.3e-60 204.4 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) SPT_ssu-like PF11779.8 KIK39114.1 - 0.11 12.1 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like Sigma_reg_N PF13800.6 KIK39114.1 - 0.12 12.7 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal YrbL-PhoP_reg PF10707.9 KIK39114.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CENP-T_C PF15511.6 KIK39116.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIK39116.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIK39116.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIK39116.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK39116.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIK39116.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit FtsJ PF01728.19 KIK39117.1 - 1.7e-42 145.5 0.0 3.6e-42 144.5 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Peptidase_S9 PF00326.21 KIK39118.1 - 3.9e-31 108.2 0.0 6.9e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KIK39118.1 - 0.00057 19.2 0.0 0.014 14.7 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK39118.1 - 0.0013 18.5 0.1 0.53 9.9 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 KIK39118.1 - 0.0029 16.3 0.2 0.024 13.3 0.0 2.3 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 KIK39118.1 - 0.014 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.18 KIK39118.1 - 0.023 14.3 0.0 0.045 13.3 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family PD40 PF07676.12 KIK39118.1 - 0.041 13.8 0.0 1.3 9.0 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat F-box-like PF12937.7 KIK39119.1 - 3.9e-08 33.1 2.3 2.4e-07 30.5 2.3 2.4 1 1 0 1 1 1 1 F-box-like RicinB_lectin_2 PF14200.6 KIK39121.1 - 3.9e-09 37.1 0.9 0.00063 20.4 0.1 2.6 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like F-box-like PF12937.7 KIK39122.1 - 0.0044 16.9 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like RicinB_lectin_2 PF14200.6 KIK39123.1 - 1.5e-06 28.8 8.5 0.0001 23.0 2.1 1.9 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Pkinase PF00069.25 KIK39124.1 - 7.3e-10 38.6 0.0 8.5e-10 38.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK39124.1 - 0.0038 16.5 0.0 0.0045 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase ATP-synt_E PF05680.12 KIK39125.1 - 0.019 15.3 4.6 0.027 14.8 4.6 1.3 1 0 0 1 1 1 0 ATP synthase E chain VCH_CASS14 PF18315.1 KIK39125.1 - 0.032 14.3 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Integron cassette protein VCH_CASS1 chain RETICULATA-like PF11891.8 KIK39125.1 - 0.073 12.9 0.2 0.094 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein RETICULATA-related Exo_endo_phos PF03372.23 KIK39126.1 - 2.1e-21 76.5 0.9 1.3e-19 70.7 0.9 2.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 KIK39126.1 - 2.6e-12 46.7 3.6 8.5e-07 29.2 0.8 2.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIK39126.1 - 5.2e-11 42.1 3.3 1.9e-10 40.4 2.7 2.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KIK39126.1 - 2 9.3 8.6 15 6.6 0.4 4.6 3 1 1 4 4 4 0 Leucine Rich Repeat MDD_C PF18376.1 KIK39127.1 - 7.5e-71 237.7 0.0 9.8e-71 237.4 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KIK39127.1 - 8.1e-09 35.6 1.1 1.8e-08 34.5 1.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Muskelin_N PF06588.11 KIK39128.1 - 1.6e-31 109.8 0.1 3.4e-31 108.7 0.0 1.6 2 0 0 2 2 2 1 Muskelin N-terminus Kelch_3 PF13415.6 KIK39128.1 - 5.8e-24 83.9 4.3 1.6e-08 34.6 0.0 5.8 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KIK39128.1 - 4.5e-22 77.8 3.1 2.5e-09 37.0 0.0 5.2 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KIK39128.1 - 6.9e-21 73.8 4.9 1.4e-06 28.2 0.1 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 KIK39128.1 - 2e-17 62.7 3.1 0.00012 22.2 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KIK39128.1 - 1.1e-13 50.6 3.8 9.7e-08 31.5 0.4 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 KIK39128.1 - 5.8e-05 22.9 3.9 0.0041 17.1 0.2 4.2 4 0 0 4 4 4 1 Kelch motif BLM10_mid PF16507.5 KIK39128.1 - 0.17 10.5 0.7 1.4 7.5 0.0 2.0 2 0 0 2 2 2 0 Proteasome-substrate-size regulator, mid region peroxidase PF00141.23 KIK39129.1 - 3.8e-46 157.6 0.0 6.1e-46 157.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase FANCI_S4 PF14678.6 KIK39130.1 - 0.14 11.3 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 FANCI solenoid 4 zf-LYAR PF08790.11 KIK39131.1 - 1.2e-13 50.7 4.6 2.8e-13 49.5 4.6 1.7 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger DUF5539 PF17693.1 KIK39132.1 - 0.73 9.5 5.5 0.72 9.5 4.7 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5539) Autophagy_N PF03986.13 KIK39133.1 - 3.7e-41 140.3 0.1 7.1e-41 139.4 0.0 1.5 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 KIK39133.1 - 5e-18 65.4 0.3 9.6e-18 64.5 0.3 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 KIK39133.1 - 1.2e-12 47.1 2.9 2.4e-12 46.1 2.9 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Ground-like PF04155.18 KIK39138.1 - 0.14 12.8 0.1 0.41 11.3 0.0 1.7 2 0 0 2 2 2 0 Ground-like domain PIG-U PF06728.13 KIK39140.1 - 7e-96 321.6 21.4 7.9e-96 321.4 21.4 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 KIK39140.1 - 4 7.1 10.7 0.066 12.9 0.9 2.1 2 0 0 2 2 2 0 8TM Microsporidial transmembrane domain Misat_Tub_SegII PF10644.9 KIK39142.1 - 4.4e-35 120.5 0.4 7.5e-35 119.8 0.4 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KIK39142.1 - 6.2e-27 94.4 0.1 2.4e-26 92.5 0.0 1.9 2 0 0 2 2 2 1 Tubulin domain Tubulin PF00091.25 KIK39142.1 - 0.00069 19.9 0.0 1.2 9.3 0.0 2.4 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Cerato-platanin PF07249.12 KIK39145.1 - 1e-10 41.8 0.8 4.8e-08 33.1 0.0 2.1 2 0 0 2 2 2 2 Cerato-platanin GMP_synt_C PF00958.22 KIK39145.1 - 0.15 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 GMP synthase C terminal domain Metallophos PF00149.28 KIK39146.1 - 3.9e-36 125.5 0.0 5.4e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KIK39146.1 - 0.00085 19.0 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Metallophos_2 PF12850.7 KIK39146.1 - 0.18 12.0 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain WD40 PF00400.32 KIK39147.1 - 1.4e-26 92.2 11.2 1e-08 35.6 0.1 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39147.1 - 5e-12 46.0 0.0 0.082 13.2 0.0 4.1 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KIK39147.1 - 0.0025 18.3 1.2 0.57 10.8 0.1 3.8 4 0 0 4 4 4 1 PQQ-like domain Ge1_WD40 PF16529.5 KIK39147.1 - 0.003 16.6 0.0 0.28 10.1 0.0 3.1 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KIK39147.1 - 0.016 14.8 0.8 0.35 10.4 0.3 2.2 1 1 1 2 2 2 0 PQQ-like domain Trp_ring PF18669.1 KIK39147.1 - 0.021 15.0 0.1 9.8 6.4 0.0 3.3 2 1 1 3 3 3 0 Trimeric autotransporter adhesin Trp ring domain FCP1_C PF09309.10 KIK39147.1 - 0.25 11.2 0.0 0.7 9.7 0.0 1.6 1 1 1 2 2 2 0 FCP1, C-terminal EMC1_C PF07774.13 KIK39148.1 - 1.7e-74 250.1 0.0 3.2e-74 249.2 0.0 1.5 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KIK39148.1 - 1.2e-11 44.7 1.2 0.0014 18.3 0.0 3.5 2 1 1 3 3 3 3 PQQ-like domain PQQ PF01011.21 KIK39148.1 - 5.5e-09 35.5 0.3 0.0053 16.6 0.1 4.7 5 0 0 5 5 5 2 PQQ enzyme repeat PQQ_3 PF13570.6 KIK39148.1 - 0.18 12.3 6.7 0.65 10.6 0.2 4.0 4 0 0 4 4 4 0 PQQ-like domain Cys_Met_Meta_PP PF01053.20 KIK39151.1 - 1.7e-42 145.3 0.0 5.9e-42 143.5 0.0 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KIK39151.1 - 0.00017 21.0 0.7 0.0021 17.5 0.7 2.1 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KIK39151.1 - 0.068 12.4 0.2 2.5 7.3 0.2 2.2 1 1 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 KIK39151.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V IMUP PF15761.5 KIK39151.1 - 0.97 10.2 5.1 10 6.9 0.3 2.6 1 1 1 2 2 2 0 Immortalisation up-regulated protein Plavaka PF18759.1 KIK39154.1 - 6.6e-34 117.6 0.0 1.1e-33 116.9 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase SDA1 PF05285.12 KIK39154.1 - 0.15 11.5 4.3 0.28 10.6 4.3 1.4 1 0 0 1 1 1 0 SDA1 Hydrophobin PF01185.18 KIK39158.1 - 5.6e-22 78.2 9.5 5.6e-22 78.2 9.5 1.5 2 0 0 2 2 2 1 Fungal hydrophobin Conotoxin PF02950.17 KIK39158.1 - 2.3 9.3 7.8 6 8.0 1.6 2.3 2 0 0 2 2 2 0 Conotoxin SIMPL PF04402.14 KIK39159.1 - 0.17 12.3 1.4 0.18 12.2 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF541) DUF4203 PF13886.6 KIK39161.1 - 7.9e-17 61.6 22.6 9.7e-17 61.3 22.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Mito_carr PF00153.27 KIK39162.1 - 4.5e-68 225.3 1.6 5.9e-23 80.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein FSH1 PF03959.13 KIK39163.1 - 1.6e-56 191.4 0.0 1.8e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KIK39163.1 - 0.016 14.9 0.0 2.3 7.8 0.0 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold zf-C2H2_4 PF13894.6 KIK39164.1 - 0.0001 22.8 3.9 0.026 15.4 0.8 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf_UBZ PF18439.1 KIK39164.1 - 0.0025 17.4 0.0 0.2 11.2 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 KIK39164.1 - 0.0039 17.5 0.1 0.34 11.4 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 KIK39164.1 - 0.023 15.1 0.7 0.023 15.1 0.7 3.1 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KIK39164.1 - 0.038 14.0 0.3 0.076 13.0 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger FOXP-CC PF16159.5 KIK39164.1 - 0.043 14.4 0.7 0.043 14.4 0.7 1.7 2 1 0 2 2 2 0 FOXP coiled-coil domain DUF2757 PF10955.8 KIK39164.1 - 0.063 13.5 0.1 0.085 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) Actin_micro PF17003.5 KIK39164.1 - 0.11 11.6 2.2 0.078 12.2 0.8 1.4 2 0 0 2 2 2 0 Putative actin-like family zf-C2H2_12 PF18658.1 KIK39164.1 - 0.42 10.2 4.8 0.64 9.6 0.2 2.3 1 1 1 2 2 2 0 Zinc-finger C2H2-type Rit1_C PF17184.4 KIK39166.1 - 9.4e-97 323.7 0.0 1.2e-96 323.4 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KIK39166.1 - 3.6e-31 107.7 0.0 1.1e-30 106.2 0.0 1.9 2 0 0 2 2 2 1 Rit1 DUSP-like domain Peptidase_C2 PF00648.21 KIK39167.1 - 6.3e-23 81.2 0.0 1.3e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KIK39167.1 - 8.2e-17 61.8 0.3 1.4e-09 38.4 0.0 3.6 3 0 0 3 3 3 2 Calpain large subunit, domain III MIT PF04212.18 KIK39167.1 - 1.4e-06 28.2 3.5 2.9e-06 27.3 3.5 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain SNAP PF14938.6 KIK39167.1 - 0.022 14.2 0.9 0.035 13.5 0.9 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP APCDDC PF14921.6 KIK39167.1 - 0.18 11.2 1.4 13 5.1 0.1 3.1 3 0 0 3 3 3 0 Adenomatosis polyposis coli down-regulated 1 LRR_8 PF13855.6 KIK39168.1 - 3.2e-08 33.2 26.3 0.00051 19.8 7.9 4.8 3 1 3 6 6 6 4 Leucine rich repeat LRRNT_2 PF08263.12 KIK39168.1 - 0.00019 21.7 0.3 0.00076 19.7 0.3 2.1 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain EVI2A PF05399.11 KIK39168.1 - 0.011 15.3 0.7 0.022 14.4 0.7 1.5 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) LRR_5 PF13306.6 KIK39168.1 - 0.075 13.0 1.6 0.13 12.2 0.4 1.9 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) SNARE PF05739.19 KIK39168.1 - 0.19 11.8 3.5 0.3 11.1 3.5 1.3 1 0 0 1 1 1 0 SNARE domain LRR_4 PF12799.7 KIK39168.1 - 1.1 9.8 31.2 0.25 11.8 5.5 5.4 1 1 3 4 4 4 0 Leucine Rich repeats (2 copies) MFS_1 PF07690.16 KIK39170.1 - 9.2e-22 77.4 33.4 1.6e-21 76.6 31.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 KIK39171.1 - 2.5e-56 191.4 0.0 3.9e-55 187.4 0.0 2.4 1 1 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 KIK39172.1 - 4.8e-37 125.3 13.2 2.3e-06 28.2 0.3 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39172.1 - 2e-11 44.0 0.1 0.17 12.2 0.0 6.0 2 1 6 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 KIK39172.1 - 3.5e-09 37.1 3.7 2.5e-07 31.2 0.4 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ge1_WD40 PF16529.5 KIK39172.1 - 6.8e-08 31.8 0.2 0.0001 21.4 0.0 3.5 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_2 PF07719.17 KIK39172.1 - 2.7e-06 27.1 11.7 0.51 10.6 0.3 7.4 8 1 1 9 9 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK39172.1 - 1.7e-05 24.4 3.3 0.37 10.7 0.1 6.4 8 0 0 8 8 8 1 Tetratricopeptide repeat eIF2A PF08662.11 KIK39172.1 - 3e-05 24.0 0.0 0.3 10.9 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A TPR_7 PF13176.6 KIK39172.1 - 0.0013 18.6 0.9 5.6 7.2 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK39172.1 - 0.0072 17.1 11.1 12 7.0 0.1 5.6 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK39172.1 - 0.017 14.8 0.2 0.28 10.9 0.1 2.8 2 0 0 2 2 2 0 TPR repeat DUF3050 PF11251.8 KIK39172.1 - 0.07 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) PD40 PF07676.12 KIK39172.1 - 0.074 13.0 0.5 8.4 6.5 0.0 3.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF3856 PF12968.7 KIK39172.1 - 0.12 12.5 1.3 1.2e+02 2.7 0.0 4.3 5 0 0 5 5 4 0 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 KIK39172.1 - 0.37 11.3 15.0 10 6.7 0.1 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK39172.1 - 0.44 11.2 14.8 0.67 10.7 2.6 5.1 5 1 0 5 5 4 0 Tetratricopeptide repeat DUF779 PF05610.11 KIK39173.1 - 0.11 12.7 0.1 0.13 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF779) WD40 PF00400.32 KIK39175.1 - 6.4e-20 71.1 1.7 2.7e-06 28.0 0.0 3.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39175.1 - 4.4e-05 23.7 0.0 0.032 14.5 0.1 2.8 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK39175.1 - 0.00072 18.6 0.0 0.014 14.3 0.0 2.3 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK39175.1 - 0.001 17.8 0.1 0.0011 17.7 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KIK39175.1 - 0.004 16.0 0.0 0.037 12.8 0.0 1.9 1 1 1 2 2 2 1 Nup133 N terminal like DUF1513 PF07433.11 KIK39175.1 - 0.047 12.8 0.0 0.08 12.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1513) FlaE PF07559.14 KIK39175.1 - 0.14 12.8 0.0 0.21 12.2 0.0 1.5 1 1 0 1 1 1 0 Flagellar basal body protein FlaE p450 PF00067.22 KIK39178.1 - 4.2e-64 217.0 0.0 5.2e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hydrophobin PF01185.18 KIK39179.1 - 7.8e-22 77.7 13.9 9.1e-22 77.5 13.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF4538 PF15061.6 KIK39179.1 - 0.17 11.7 0.2 0.35 10.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Ank_4 PF13637.6 KIK39180.1 - 2e-17 63.3 2.4 1.1e-07 32.3 0.2 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK39180.1 - 3.2e-14 53.3 0.1 1.1e-05 25.9 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIK39180.1 - 2.5e-13 49.9 1.6 7.7e-08 32.5 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK39180.1 - 1.5e-12 46.5 1.3 0.00075 19.8 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KIK39180.1 - 1.6e-12 47.3 7.9 3.7e-06 27.1 0.2 3.4 4 0 0 4 4 4 2 Ankyrin repeat DUF5598 PF18127.1 KIK39181.1 - 0.14 12.6 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5598) Hydrolase_like PF13242.6 KIK39182.1 - 1e-23 83.2 0.0 2.2e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KIK39182.1 - 1.4e-21 76.5 0.0 2.2e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KIK39182.1 - 0.0031 17.6 0.0 0.0051 16.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase FMO-like PF00743.19 KIK39185.1 - 4.2e-21 75.0 0.0 1.2e-20 73.5 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK39185.1 - 7.6e-20 71.4 0.0 2.2e-18 66.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK39185.1 - 3.8e-14 52.6 0.3 1.9e-10 40.5 0.3 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK39185.1 - 9.2e-11 41.5 0.0 4.4e-08 32.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KIK39185.1 - 3e-10 40.5 0.3 0.0011 19.4 0.0 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIK39185.1 - 4.8e-07 29.3 1.2 0.0023 17.2 0.5 3.2 2 1 1 3 3 3 1 FAD binding domain 3HCDH_N PF02737.18 KIK39185.1 - 1.7e-05 24.8 0.2 0.028 14.3 0.1 3.1 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 KIK39185.1 - 2.8e-05 24.3 0.1 0.0009 19.4 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIK39185.1 - 3.1e-05 23.3 0.2 0.0015 17.8 0.0 2.5 3 0 0 3 3 3 1 Thi4 family Shikimate_DH PF01488.20 KIK39185.1 - 4e-05 23.7 0.2 0.029 14.4 0.0 2.6 3 0 0 3 3 2 2 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KIK39185.1 - 0.0002 20.6 1.1 1.2 8.1 0.1 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 KIK39185.1 - 0.00064 19.1 0.0 0.19 11.1 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KIK39185.1 - 0.00092 18.4 1.1 0.15 11.1 0.1 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KIK39185.1 - 0.0038 17.2 0.0 1.3 9.0 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KIK39185.1 - 0.0039 16.3 4.0 0.16 11.0 0.9 2.5 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 KIK39185.1 - 0.0045 16.6 4.3 0.066 12.8 1.0 3.3 3 1 0 4 4 4 1 FAD dependent oxidoreductase TrkA_N PF02254.18 KIK39185.1 - 0.024 14.9 0.3 5.3 7.3 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.14 KIK39185.1 - 0.04 12.6 1.7 0.39 9.4 0.1 2.5 3 0 0 3 3 3 0 HI0933-like protein Malic_M PF03949.15 KIK39185.1 - 0.099 11.9 0.1 2.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain XdhC_C PF13478.6 KIK39185.1 - 0.12 12.9 0.0 17 5.9 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain FAD_oxidored PF12831.7 KIK39185.1 - 0.22 10.8 4.5 14 4.9 0.1 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase F-box-like PF12937.7 KIK39186.1 - 0.0011 18.8 0.6 0.0034 17.3 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK39186.1 - 0.0017 18.2 0.1 0.0046 16.8 0.1 1.8 1 0 0 1 1 1 1 F-box domain DUF1932 PF09130.11 KIK39187.1 - 2.6e-15 56.1 0.1 6.2e-15 54.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 KIK39187.1 - 7.8e-12 45.6 0.0 1.5e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KIK39187.1 - 1.7e-05 24.5 0.0 2.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KIK39187.1 - 2.9e-05 24.5 0.0 6.2e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KIK39187.1 - 6.9e-05 22.3 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.9 KIK39187.1 - 0.02 14.8 0.2 0.047 13.6 0.2 1.6 1 0 0 1 1 1 0 Rossmann-like domain 3HCDH_N PF02737.18 KIK39187.1 - 0.032 14.1 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KIK39187.1 - 0.042 13.5 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PDH PF02153.17 KIK39187.1 - 0.083 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Prephenate dehydrogenase RhoGAP PF00620.27 KIK39188.1 - 9.7e-30 103.4 0.0 1.6e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 KIK39188.1 - 1e-29 103.2 0.0 2.9e-29 101.7 0.0 1.8 1 0 0 1 1 1 1 MyTH4 domain WW PF00397.26 KIK39188.1 - 9.9e-10 38.3 5.0 8.4e-05 22.6 3.2 2.6 2 0 0 2 2 2 2 WW domain Allexi_40kDa PF05549.11 KIK39189.1 - 0.049 13.2 0.2 0.077 12.5 0.2 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein TAN PF11640.8 KIK39189.1 - 0.086 13.0 0.3 0.3 11.2 0.1 1.9 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Glyco_hydro_63 PF03200.16 KIK39189.1 - 0.1 11.4 0.3 5.1 5.7 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 63 C-terminal domain BTB PF00651.31 KIK39190.1 - 7.9e-05 22.9 0.0 0.00015 22.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain KDZ PF18758.1 KIK39195.1 - 2.3e-38 132.0 1.7 4.4e-38 131.1 1.7 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK39195.1 - 2.5e-23 82.3 0.2 2.5e-23 82.3 0.2 3.0 2 1 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK39195.1 - 0.035 14.2 0.0 0.13 12.4 0.0 2.0 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases RNase_3_N PF18497.1 KIK39198.1 - 0.12 12.6 0.1 0.42 10.9 0.1 1.8 2 0 0 2 2 2 0 Ribonuclease III N-terminal domain Herpes_UL92 PF03048.14 KIK39202.1 - 0.03 14.1 0.5 0.031 14.1 0.5 1.0 1 0 0 1 1 1 0 UL92 family MerR PF00376.23 KIK39205.1 - 0.0029 17.3 0.1 0.01 15.6 0.0 1.9 2 0 0 2 2 2 1 MerR family regulatory protein BTB PF00651.31 KIK39206.1 - 8.5e-05 22.8 0.0 0.00016 21.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Peptidase_C48 PF02902.19 KIK39208.1 - 0.026 14.4 0.2 0.31 10.8 0.2 2.1 1 1 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain ALG11_N PF15924.5 KIK39211.1 - 0.024 14.7 0.1 0.029 14.4 0.1 1.1 1 0 0 1 1 1 0 ALG11 mannosyltransferase N-terminus zf-CCHC_4 PF14392.6 KIK39212.1 - 0.047 13.4 4.7 0.1 12.4 4.7 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 KIK39212.1 - 0.052 13.7 9.2 0.24 11.6 4.5 2.5 2 1 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 KIK39212.1 - 3.4 7.6 19.6 0.35 10.8 7.7 2.6 1 1 1 2 2 2 0 Zinc knuckle Plk4_PB2 PF18409.1 KIK39219.1 - 0.054 14.2 0.1 0.083 13.6 0.1 1.4 1 1 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 Eapp_C PF10238.9 KIK39222.1 - 0.027 14.6 0.2 0.057 13.5 0.2 1.5 1 0 0 1 1 1 0 E2F-associated phosphoprotein Asparaginase_2 PF01112.18 KIK39223.1 - 7.6e-76 255.1 0.0 1.5e-54 185.1 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Dynamitin PF04912.14 KIK39224.1 - 3.2e-58 197.9 1.3 1.5e-57 195.7 1.3 1.8 1 1 0 1 1 1 1 Dynamitin ABC_tran_CTD PF16326.5 KIK39224.1 - 0.0064 16.7 1.9 0.49 10.7 0.0 3.2 3 1 0 3 3 3 1 ABC transporter C-terminal domain NIT PF08376.10 KIK39224.1 - 0.14 12.6 3.4 0.11 12.9 0.7 2.1 2 0 0 2 2 2 0 Nitrate and nitrite sensing SlyX PF04102.12 KIK39224.1 - 4.6 7.9 8.9 7 7.3 0.6 3.8 5 0 0 5 5 5 0 SlyX Con-6 PF10346.9 KIK39225.1 - 1.1e-45 153.3 14.4 7.5e-16 57.9 1.3 3.3 3 0 0 3 3 3 3 Conidiation protein 6 DUF1539 PF07560.11 KIK39225.1 - 0.0094 16.0 0.3 9 6.4 0.0 2.9 1 1 2 3 3 3 2 Domain of Unknown Function (DUF1539) GA-like PF17573.2 KIK39225.1 - 0.016 15.1 5.7 3.8 7.5 0.2 3.4 3 0 0 3 3 3 0 GA-like domain PASTA PF03793.19 KIK39225.1 - 0.019 14.8 0.0 6.8 6.6 0.0 3.0 3 0 0 3 3 3 0 PASTA domain SpoIIIAH PF12685.7 KIK39225.1 - 0.02 14.7 5.6 1 9.2 0.0 2.8 1 1 1 2 2 2 0 SpoIIIAH-like protein ATP-synt_DE PF00401.20 KIK39225.1 - 1 9.6 12.3 5.4 7.4 1.2 3.6 3 0 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain YhzD PF14120.6 KIK39225.1 - 1.2 9.3 10.0 71 3.6 0.1 4.6 4 1 0 4 4 4 0 YhzD-like protein HbrB PF08539.11 KIK39226.1 - 6.7e-56 188.9 0.0 1.5e-55 187.8 0.0 1.6 1 0 0 1 1 1 1 HbrB-like SpoVAC_SpoVAEB PF03862.13 KIK39227.1 - 0.16 12.2 0.2 0.25 11.7 0.2 1.3 1 0 0 1 1 1 0 SpoVAC/SpoVAEB sporulation membrane protein Transferase PF02458.15 KIK39228.1 - 0.0016 17.2 0.0 0.0036 16.0 0.0 1.4 1 1 0 2 2 2 1 Transferase family adh_short PF00106.25 KIK39229.1 - 1.3e-24 86.7 0.0 1.8e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK39229.1 - 1.2e-23 83.9 0.0 1.5e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK39229.1 - 2.6e-06 27.5 0.0 4.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KIK39231.1 - 9.6e-28 97.0 0.0 1.2e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK39231.1 - 9.2e-19 67.9 0.0 1.1e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK39231.1 - 8e-06 25.9 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KIK39231.1 - 4.7e-05 23.4 0.0 6.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KIK39231.1 - 0.0055 15.8 0.0 0.008 15.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KIK39231.1 - 0.067 12.7 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family VSP PF03302.13 KIK39236.1 - 0.03 13.2 0.6 0.04 12.8 0.6 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein SKG6 PF08693.10 KIK39236.1 - 0.057 12.8 3.2 0.11 11.9 3.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Herpes_gE PF02480.16 KIK39236.1 - 0.18 10.6 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E MGC-24 PF05283.11 KIK39236.1 - 0.24 11.8 4.0 0.1 13.0 0.8 1.9 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin COG5 PF10392.9 KIK39237.1 - 4.1e-24 85.2 3.1 4.2e-24 85.2 0.9 2.3 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.11 KIK39237.1 - 0.00078 19.5 0.1 0.009 16.1 0.1 2.6 1 1 0 1 1 1 1 Vps51/Vps67 Zw10 PF06248.13 KIK39237.1 - 0.034 12.7 0.2 0.067 11.8 0.2 1.4 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 FlaC_arch PF05377.11 KIK39237.1 - 0.044 14.2 0.1 3.7 8.0 0.0 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) GLTP PF08718.11 KIK39237.1 - 0.13 12.5 0.7 1.5 9.1 0.2 2.6 2 0 0 2 2 2 0 Glycolipid transfer protein (GLTP) THOC7 PF05615.13 KIK39237.1 - 0.71 10.2 3.3 2.7 8.3 0.2 2.6 2 1 1 3 3 3 0 Tho complex subunit 7 Baculo_PEP_C PF04513.12 KIK39237.1 - 0.76 9.8 3.0 5.2 7.1 0.4 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.11 KIK39237.1 - 1 9.4 5.3 1 9.5 0.3 3.0 2 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Ten1_2 PF15490.6 KIK39238.1 - 0.00016 21.3 0.0 0.00022 20.9 0.0 1.3 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit adh_short PF00106.25 KIK39240.1 - 1.4e-39 135.6 0.2 1.8e-39 135.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK39240.1 - 2.6e-32 112.3 0.1 3.2e-32 111.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK39240.1 - 6e-08 32.8 0.1 8.1e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KIK39240.1 - 4.7e-07 29.5 0.0 6.2e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) AIRS PF00586.24 KIK39240.1 - 0.033 14.8 0.1 0.047 14.3 0.1 1.5 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain NAD_binding_3 PF03447.16 KIK39240.1 - 0.081 13.6 0.4 0.16 12.6 0.2 1.6 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain zinc_ribbon_4 PF13717.6 KIK39241.1 - 0.034 14.1 0.4 0.079 12.9 0.0 1.8 2 0 0 2 2 2 0 zinc-ribbon domain AA_permease PF00324.21 KIK39243.1 - 4e-117 391.7 44.4 5e-117 391.4 44.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK39243.1 - 5.2e-32 111.2 49.3 6.5e-32 110.9 49.3 1.1 1 0 0 1 1 1 1 Amino acid permease Evr1_Alr PF04777.13 KIK39244.1 - 2.2e-28 98.7 1.0 3.6e-28 98.0 1.0 1.3 1 0 0 1 1 1 1 Erv1 / Alr family MMR_HSR1 PF01926.23 KIK39246.1 - 7.4e-12 45.4 0.0 7.8e-12 45.3 0.0 1.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK39246.1 - 1.3e-05 24.6 0.0 1.4e-05 24.6 0.0 1.0 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIK39246.1 - 7.7e-05 22.8 0.1 0.00013 22.1 0.1 1.3 1 1 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 KIK39246.1 - 0.00018 21.5 0.0 0.00035 20.5 0.0 1.5 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KIK39246.1 - 0.00044 20.8 0.0 0.00044 20.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KIK39246.1 - 0.0068 16.8 0.0 0.01 16.2 0.0 1.4 1 1 1 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 KIK39246.1 - 0.017 14.4 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 KIK39246.1 - 0.034 14.4 0.1 3.8 7.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 KIK39246.1 - 0.044 13.3 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B IIGP PF05049.13 KIK39246.1 - 0.051 12.6 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF815 PF05673.13 KIK39246.1 - 0.087 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Septin PF00735.18 KIK39246.1 - 0.11 11.7 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_21 PF13304.6 KIK39246.1 - 0.12 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KIK39246.1 - 0.13 11.7 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KIK39246.1 - 0.14 12.4 0.1 0.17 12.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK39246.1 - 0.15 12.5 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase G-alpha PF00503.20 KIK39246.1 - 0.17 11.0 0.2 4 6.5 0.1 2.1 2 0 0 2 2 2 0 G-protein alpha subunit DUF87 PF01935.17 KIK39246.1 - 0.18 11.9 0.0 2.7 8.0 0.2 2.0 1 1 1 2 2 2 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 KIK39246.1 - 0.28 10.5 0.4 0.42 9.9 0.4 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family C2 PF00168.30 KIK39250.1 - 4.6e-14 52.6 0.0 5.7e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 C2 domain DNA_pol_B PF00136.21 KIK39251.1 - 4.2e-114 381.8 0.0 6.6e-114 381.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KIK39251.1 - 8.9e-58 195.1 0.0 1.7e-57 194.1 0.0 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KIK39251.1 - 4.9e-26 91.7 0.0 2.4e-25 89.4 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KIK39251.1 - 1.4e-22 79.5 3.2 5.7e-22 77.6 3.2 2.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal AP3D1 PF06375.11 KIK39251.1 - 0.043 14.0 4.3 1.6 8.9 0.0 2.7 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 DNA_pol_B_2 PF03175.13 KIK39251.1 - 0.15 10.9 0.0 0.39 9.5 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral tRNA_NucTran2_2 PF13735.6 KIK39251.1 - 0.18 11.7 0.1 0.4 10.7 0.1 1.5 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative RSRP PF17069.5 KIK39252.1 - 0.0022 17.6 0.0 0.003 17.2 0.0 1.1 1 0 0 1 1 1 1 Arginine/Serine-Rich protein 1 zf-C3HC PF07967.13 KIK39255.1 - 2.4e-24 85.9 0.0 3.1e-23 82.3 0.0 2.2 2 0 0 2 2 2 1 C3HC zinc finger-like Rsm1 PF08600.10 KIK39255.1 - 2.3e-16 59.7 0.6 1.7e-10 40.9 0.0 3.4 3 0 0 3 3 3 2 Rsm1-like PPR_2 PF13041.6 KIK39256.1 - 0.11 12.7 0.0 0.89 9.8 0.0 2.5 1 1 1 2 2 2 0 PPR repeat family HEAT_2 PF13646.6 KIK39256.1 - 0.12 12.8 0.0 0.88 10.0 0.0 2.3 2 0 0 2 2 2 0 HEAT repeats Ribosomal_L10 PF00466.20 KIK39258.1 - 1.1e-24 86.5 0.2 2e-24 85.6 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 KIK39258.1 - 8.8e-23 80.1 0.0 1.9e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Glyco_transf_20 PF00982.21 KIK39259.1 - 4.8e-182 605.9 0.0 2.4e-137 458.5 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 KIK39259.1 - 9.4e-05 22.9 0.0 0.00021 21.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KIK39259.1 - 0.0025 17.4 0.1 0.17 11.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Pox_I6 PF04595.13 KIK39262.1 - 0.095 11.7 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus I6-like family PetM PF08041.11 KIK39262.1 - 2.7 7.6 4.3 1.1 8.9 1.7 1.7 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 Cation_ATPase_C PF00689.21 KIK39263.1 - 1.5e-42 145.3 11.4 1.5e-42 145.3 11.4 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KIK39263.1 - 1.2e-31 109.6 7.1 1.2e-31 109.6 7.1 3.8 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KIK39263.1 - 3.2e-21 75.2 0.1 6e-21 74.3 0.1 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KIK39263.1 - 5.6e-18 66.0 0.1 3e-17 63.6 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KIK39263.1 - 5.5e-07 29.2 0.4 1.1e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KIK39263.1 - 4.4e-05 23.3 0.3 0.0022 17.8 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SPT_ssu-like PF11779.8 KIK39264.1 - 2.9e-17 62.0 3.3 3.7e-17 61.7 3.3 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like SPT_ssu-like PF11779.8 KIK39266.1 - 6.3e-07 28.9 2.4 8.4e-07 28.5 2.4 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like SAD_SRA PF02182.17 KIK39267.1 - 3.2e-53 179.6 0.0 5.9e-53 178.8 0.0 1.4 1 0 0 1 1 1 1 SAD/SRA domain SAD_SRA PF02182.17 KIK39268.1 - 2.3e-50 170.4 0.2 2.9e-50 170.0 0.2 1.1 1 0 0 1 1 1 1 SAD/SRA domain DUF761 PF05553.11 KIK39268.1 - 0.12 11.9 2.7 0.24 11.0 2.7 1.4 1 0 0 1 1 1 0 Cotton fibre expressed protein WD40 PF00400.32 KIK39269.1 - 0.0024 18.7 0.0 0.0043 17.9 0.0 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat MoCF_biosynth PF00994.24 KIK39270.1 - 6e-59 197.8 0.1 1.1e-28 99.8 0.1 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KIK39270.1 - 5.8e-35 120.4 0.0 1e-34 119.6 0.0 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KIK39270.1 - 9.4e-13 48.1 0.3 3.4e-12 46.4 0.2 2.0 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) GnsAB_toxin PF08178.11 KIK39271.1 - 0.16 12.0 0.4 0.32 10.9 0.4 1.4 1 0 0 1 1 1 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system TraC PF07820.12 KIK39271.1 - 0.81 10.1 4.6 0.58 10.5 0.3 2.4 2 0 0 2 2 2 0 TraC-like protein CLPTM1 PF05602.12 KIK39272.1 - 3.3e-147 491.0 0.0 3.8e-147 490.8 0.0 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 KIK39272.1 - 0.0004 20.1 0.9 0.0015 18.3 0.4 2.1 2 0 0 2 2 2 1 PQ loop repeat SAPIS-gp6 PF16722.5 KIK39273.1 - 0.034 14.5 1.6 0.044 14.2 0.4 1.8 1 1 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus 14-3-3 PF00244.20 KIK39275.1 - 2.4e-101 337.9 0.8 2.7e-101 337.7 0.8 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 KIK39275.1 - 0.028 14.4 0.1 0.064 13.3 0.1 1.6 1 0 0 1 1 1 0 Flagellar protein FlaF DUF1539 PF07560.11 KIK39275.1 - 0.091 12.8 0.2 0.56 10.3 0.0 2.3 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) TPR_19 PF14559.6 KIK39275.1 - 0.25 11.9 2.4 0.59 10.7 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 KIK39278.1 - 4.8e-11 42.4 0.0 5.7e-11 42.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK39278.1 - 5.5e-10 39.0 0.0 6.9e-10 38.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK39279.1 - 3.8e-12 46.0 0.0 5.1e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK39279.1 - 1.4e-07 31.1 0.0 1.8e-07 30.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KIK39280.1 - 1.3e-22 79.6 10.0 3e-06 27.9 0.3 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39280.1 - 2.6e-08 34.1 0.0 0.24 11.7 0.0 4.0 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK39280.1 - 0.00024 19.9 0.3 0.57 8.8 0.0 3.1 3 1 0 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK39280.1 - 0.00033 19.7 0.1 1.5 7.7 0.0 3.2 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK39280.1 - 0.00044 19.7 1.4 0.48 9.7 0.0 3.5 4 1 1 5 5 5 2 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK39280.1 - 0.18 11.1 0.0 9.4 5.4 0.0 2.8 2 1 0 2 2 2 0 WD40-like domain SLATT_5 PF18160.1 KIK39282.1 - 0.22 10.8 2.3 0.53 9.6 2.3 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 PLU-1 PF08429.11 KIK39283.1 - 2e-47 162.0 8.8 1.8e-46 158.9 2.5 2.9 1 1 2 3 3 3 2 PLU-1-like protein JmjC PF02373.22 KIK39283.1 - 4.7e-43 146.2 0.6 1.4e-41 141.5 0.4 2.6 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.21 KIK39283.1 - 8.4e-19 68.0 0.0 2.5e-18 66.5 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 KIK39283.1 - 4.1e-17 61.9 1.0 9.8e-17 60.6 1.0 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 KIK39283.1 - 1.4e-14 54.2 8.6 1.4e-14 54.2 8.6 2.7 2 0 0 2 2 2 1 C5HC2 zinc finger PHD PF00628.29 KIK39283.1 - 1.9e-13 50.1 51.0 7e-11 41.9 9.0 4.9 5 0 0 5 5 5 3 PHD-finger CorA PF01544.18 KIK39284.1 - 2.7e-44 151.6 0.1 3.9e-44 151.1 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 KIK39284.1 - 0.05 13.6 0.3 0.12 12.4 0.3 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TIP41 PF04176.13 KIK39287.1 - 9.1e-62 207.6 0.0 1.2e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family DLIC PF05783.11 KIK39288.1 - 4.1e-39 134.7 0.1 3.6e-33 115.1 0.0 2.8 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) Roc PF08477.13 KIK39288.1 - 0.002 18.3 0.0 0.01 16.1 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KIK39288.1 - 0.0049 17.3 0.1 0.0081 16.6 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain ABC2_membrane PF01061.24 KIK39291.1 - 9.3e-06 25.2 0.1 1.5e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter Ephrin_rec_like PF07699.13 KIK39291.1 - 0.028 14.2 1.4 0.035 13.9 0.4 1.7 2 0 0 2 2 2 0 Putative ephrin-receptor like KH_1 PF00013.29 KIK39294.1 - 4.1e-08 32.9 0.1 2.7e-06 27.1 0.1 2.4 2 0 0 2 2 2 1 KH domain Trp_repressor PF01371.19 KIK39294.1 - 0.032 14.4 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 Trp repressor protein DUF4160 PF13711.6 KIK39294.1 - 0.07 13.5 0.8 0.27 11.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) zf-C2H2 PF00096.26 KIK39295.1 - 0.044 14.3 7.0 0.11 13.0 0.2 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type Sigma70_ner PF04546.13 KIK39295.1 - 0.05 13.5 1.7 0.066 13.1 1.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Afi1 PF07792.12 KIK39295.1 - 0.099 13.1 1.0 0.17 12.3 1.0 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Nop14 PF04147.12 KIK39295.1 - 0.17 10.0 6.2 0.22 9.7 6.2 1.0 1 0 0 1 1 1 0 Nop14-like family RPN2_C PF18004.1 KIK39295.1 - 0.82 9.6 4.8 1.4 8.8 4.8 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4637 PF15470.6 KIK39295.1 - 0.9 9.3 8.6 1.5 8.5 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CDC45 PF02724.14 KIK39295.1 - 1.2 7.4 5.8 1.5 7.0 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 KIK39295.1 - 5.7 6.6 7.1 9.7 5.8 7.1 1.3 1 0 0 1 1 1 0 FAM176 family UBX PF00789.20 KIK39297.1 - 1.1e-10 41.5 0.6 2.7e-10 40.3 0.1 1.9 2 0 0 2 2 2 1 UBX domain UBA PF00627.31 KIK39297.1 - 3.3e-05 23.7 0.0 9e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Effector_1 PF04518.12 KIK39297.1 - 0.0023 17.1 3.3 0.0023 17.1 3.3 1.7 1 1 1 2 2 2 1 Effector from type III secretion system zf-C2H2 PF00096.26 KIK39297.1 - 0.07 13.6 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KIK39297.1 - 0.13 12.6 0.1 0.25 11.7 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KIK39297.1 - 0.18 12.3 0.2 0.34 11.4 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger double domain F-box PF00646.33 KIK39298.1 - 5.2e-08 32.6 1.7 1.3e-07 31.4 1.7 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK39298.1 - 0.00032 20.5 2.6 0.00056 19.8 1.4 1.9 2 0 0 2 2 2 1 F-box-like ATP-synt_D PF01813.17 KIK39299.1 - 0.46 10.3 3.5 0.45 10.3 0.5 2.1 1 1 1 2 2 2 0 ATP synthase subunit D NAD_binding_10 PF13460.6 KIK39300.1 - 3.7e-07 30.2 0.0 5.1e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIK39300.1 - 8.6e-05 22.1 0.0 0.00012 21.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KIK39300.1 - 0.0017 17.6 0.0 0.47 9.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Semialdhyde_dh PF01118.24 KIK39300.1 - 0.0027 18.1 0.0 0.0043 17.5 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain LZ_Tnp_IS66 PF13007.7 KIK39301.1 - 0.0038 18.0 2.6 0.012 16.4 2.6 1.9 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain BSP_II PF05432.11 KIK39301.1 - 0.13 11.9 7.8 0.013 15.2 3.6 1.5 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF4349 PF14257.6 KIK39301.1 - 0.32 10.4 2.5 0.52 9.7 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DNA_pol_phi PF04931.13 KIK39301.1 - 2 6.4 8.5 3 5.9 8.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi AA_permease PF00324.21 KIK39302.1 - 2e-127 425.7 38.4 2.5e-127 425.4 38.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK39302.1 - 2.1e-30 105.9 44.3 2.6e-30 105.6 44.3 1.1 1 0 0 1 1 1 1 Amino acid permease Ferritin PF00210.24 KIK39302.1 - 0.016 15.2 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 Ferritin-like domain Ytp1 PF10355.9 KIK39305.1 - 3.2e-55 187.3 17.3 3.2e-55 187.3 17.3 2.6 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KIK39305.1 - 5.9e-26 90.3 2.3 5.9e-26 90.3 2.3 3.3 3 1 1 4 4 4 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 KIK39305.1 - 0.00028 21.0 3.0 0.00028 21.0 3.0 3.5 3 2 0 3 3 3 1 Eukaryotic cytochrome b561 Cellulase PF00150.18 KIK39306.1 - 2.2e-15 56.8 0.4 1.3e-14 54.3 0.4 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RAP1 PF07218.11 KIK39306.1 - 0.11 10.8 5.4 0.16 10.2 5.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Prenyltrans PF00432.21 KIK39308.1 - 4.8e-59 195.8 6.5 1.8e-12 46.8 0.1 5.8 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KIK39308.1 - 1.6e-06 27.5 0.0 0.014 14.5 0.0 3.7 2 1 2 4 4 4 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KIK39308.1 - 0.00093 18.4 0.0 0.0027 16.9 0.0 1.6 1 1 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain F-box-like PF12937.7 KIK39309.1 - 0.00013 21.8 0.0 0.00058 19.7 0.0 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK39309.1 - 0.0088 15.9 0.2 0.041 13.8 0.0 2.3 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KIK39309.1 - 0.08 13.4 0.0 0.08 13.4 0.0 5.8 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) CDC48_N PF02359.18 KIK39310.1 - 2.2e-20 72.6 0.3 3e-20 72.2 0.3 1.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Molydop_binding PF01568.21 KIK39310.1 - 0.023 14.7 0.0 0.041 13.9 0.0 1.4 1 1 0 1 1 1 0 Molydopterin dinucleotide binding domain SH3_2 PF07653.17 KIK39310.1 - 0.036 13.7 0.0 0.47 10.2 0.0 2.1 1 1 1 2 2 2 0 Variant SH3 domain eIF-1a PF01176.19 KIK39310.1 - 0.087 12.6 0.7 12 5.8 0.1 2.4 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 adh_short PF00106.25 KIK39311.1 - 6.7e-05 22.4 0.0 0.0072 15.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase Ureidogly_lyase PF04115.12 KIK39312.1 - 0.12 12.1 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Ureidoglycolate lyase DUF1690 PF07956.11 KIK39313.1 - 0.018 15.4 0.1 0.021 15.2 0.1 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) SepF PF04472.12 KIK39313.1 - 0.04 14.2 0.1 0.056 13.7 0.1 1.3 1 1 0 1 1 1 0 Cell division protein SepF Ribosomal_L18A PF01775.17 KIK39313.1 - 0.05 13.7 0.0 0.064 13.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A CLZ PF16526.5 KIK39313.1 - 0.11 12.9 0.2 0.14 12.5 0.2 1.3 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Nnf1 PF03980.14 KIK39314.1 - 4.8e-13 49.4 1.4 7.5e-13 48.8 1.4 1.3 1 0 0 1 1 1 1 Nnf1 ABC_tran_CTD PF16326.5 KIK39314.1 - 0.03 14.6 3.5 0.06 13.6 3.5 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain ZapB PF06005.12 KIK39314.1 - 0.083 13.3 1.1 0.14 12.6 1.1 1.4 1 0 0 1 1 1 0 Cell division protein ZapB K-box PF01486.17 KIK39314.1 - 0.085 13.0 0.7 0.16 12.1 0.2 1.7 2 0 0 2 2 2 0 K-box region DivIC PF04977.15 KIK39314.1 - 0.16 11.7 3.6 0.12 12.2 1.8 1.7 2 0 0 2 2 2 0 Septum formation initiator ADIP PF11559.8 KIK39314.1 - 0.58 10.2 4.4 2.1 8.4 4.4 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding zf-RING_2 PF13639.6 KIK39315.1 - 1.2e-08 35.2 9.2 1.7e-07 31.4 9.2 2.3 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KIK39315.1 - 1.5e-07 31.6 6.8 3.5e-07 30.4 6.8 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KIK39315.1 - 2.5e-06 27.1 2.6 0.0026 17.5 0.1 2.6 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4_2 PF13923.6 KIK39315.1 - 7e-06 25.8 8.8 7.8e-06 25.6 3.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK39315.1 - 1.5e-05 24.7 3.9 2.7e-05 23.9 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK39315.1 - 0.00018 21.4 2.5 0.00039 20.3 2.5 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KIK39315.1 - 0.00043 20.1 4.2 0.00045 20.0 1.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK39315.1 - 0.00061 19.8 0.2 0.0018 18.2 0.1 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KIK39315.1 - 0.00099 19.1 0.5 0.0024 17.9 0.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KIK39315.1 - 0.0097 15.5 1.2 0.0097 15.5 1.2 1.7 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KIK39315.1 - 0.01 15.7 5.4 0.026 14.4 5.5 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 ER_lumen_recept PF00810.18 KIK39315.1 - 0.046 14.5 1.2 0.13 13.1 1.2 1.8 1 0 0 1 1 1 0 ER lumen protein retaining receptor zf-C3H2C3 PF17122.5 KIK39315.1 - 0.13 12.3 2.5 0.34 11.0 2.5 1.7 1 0 0 1 1 1 0 Zinc-finger zf-P11 PF03854.14 KIK39315.1 - 0.68 9.6 3.7 1.6 8.4 3.7 1.5 1 0 0 1 1 1 0 P-11 zinc finger Methyltransf_16 PF10294.9 KIK39316.1 - 2.1e-24 86.2 0.0 2.9e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KIK39316.1 - 0.0089 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Rhomboid PF01694.22 KIK39317.1 - 4.5e-18 65.7 18.3 3.2e-17 62.9 18.3 2.2 1 1 0 1 1 1 1 Rhomboid family Anoctamin PF04547.12 KIK39317.1 - 0.04 12.8 0.4 0.057 12.2 0.4 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel ATP-synt_J PF04911.12 KIK39317.1 - 0.13 11.8 0.4 0.78 9.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase j chain HSP20 PF00011.21 KIK39318.1 - 9.6e-26 89.9 0.3 3e-25 88.3 0.3 1.7 1 1 1 2 2 2 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIK39318.1 - 3.2e-10 39.4 0.0 5.2e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA COX4_pro_2 PF07835.12 KIK39318.1 - 0.14 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV FAD_binding_3 PF01494.19 KIK39319.1 - 1.9e-23 83.3 0.1 1.9e-12 47.1 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KIK39319.1 - 2.8e-08 33.2 3.0 2.6e-06 26.8 1.8 3.2 3 1 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KIK39319.1 - 3.2e-06 27.2 0.1 2.2e-05 24.5 0.1 2.1 1 1 0 1 1 1 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KIK39319.1 - 3.9e-05 22.7 0.2 0.0045 15.9 0.3 2.9 2 1 1 3 3 3 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 KIK39319.1 - 6.2e-05 22.4 0.1 0.00024 20.4 0.1 1.7 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KIK39319.1 - 0.00017 20.8 0.0 0.00027 20.1 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 KIK39319.1 - 0.00062 19.4 0.3 0.0014 18.3 0.2 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIK39319.1 - 0.00097 18.4 0.1 0.0037 16.5 0.0 2.0 3 0 0 3 3 3 1 Thi4 family NAD_binding_8 PF13450.6 KIK39319.1 - 0.0016 18.6 0.2 0.0044 17.2 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIK39319.1 - 0.014 14.7 0.1 0.04 13.2 0.2 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK39319.1 - 0.025 13.7 1.2 0.06 12.4 1.0 1.7 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 KIK39319.1 - 0.03 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIK39319.1 - 0.058 14.0 0.5 0.33 11.5 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK39319.1 - 0.062 12.0 0.3 0.11 11.2 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein Sec6 PF06046.13 KIK39320.1 - 8e-149 496.7 2.0 2.6e-148 495.0 0.1 2.0 2 0 0 2 2 2 1 Exocyst complex component Sec6 HECT PF00632.25 KIK39320.1 - 0.0022 17.5 0.1 0.0043 16.6 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Fes1 PF08609.10 KIK39320.1 - 0.017 16.0 4.5 0.28 12.1 0.3 4.1 3 1 0 3 3 3 0 Nucleotide exchange factor Fes1 Vps53_N PF04100.12 KIK39320.1 - 0.09 11.7 8.2 0.29 10.1 3.6 2.8 1 1 0 2 2 2 0 Vps53-like, N-terminal CN_hydrolase PF00795.22 KIK39321.1 - 2.9e-38 131.7 0.0 4.3e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KIK39321.1 - 2.3e-22 79.3 0.0 7.3e-22 77.7 0.0 1.7 1 1 0 1 1 1 1 NAD synthase EAP30 PF04157.16 KIK39323.1 - 1.6e-65 220.7 0.1 1.8e-65 220.5 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family DUF4351 PF14261.6 KIK39323.1 - 0.22 11.6 1.2 0.38 10.8 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) p450 PF00067.22 KIK39325.1 - 2.2e-69 234.4 0.0 2.5e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box PF00646.33 KIK39326.1 - 9.8e-05 22.1 1.9 0.00022 21.0 0.8 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIK39326.1 - 0.0028 17.5 0.5 0.008 16.1 0.5 1.8 1 0 0 1 1 1 1 F-box-like Adaptin_N PF01602.20 KIK39327.1 - 1.9e-143 478.8 6.0 2.2e-143 478.6 6.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KIK39327.1 - 2e-24 86.1 1.5 4.8e-24 84.8 1.5 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KIK39327.1 - 1.8e-07 31.4 9.7 2.5e-06 27.7 0.6 4.5 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIK39327.1 - 0.0047 17.3 1.7 3.2 8.2 0.1 4.3 4 2 0 4 4 4 1 HEAT repeats HEAT PF02985.22 KIK39327.1 - 0.034 14.4 0.5 71 4.1 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat Forkhead PF00250.18 KIK39329.1 - 3.4e-26 91.3 0.0 6.3e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain Cu-oxidase PF00394.22 KIK39330.1 - 1.9e-46 158.1 0.0 5e-41 140.5 0.0 3.3 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK39330.1 - 4.8e-40 136.5 1.2 4.6e-36 123.6 0.1 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK39330.1 - 1.6e-38 131.4 1.5 1.2e-37 128.5 0.3 2.5 2 0 0 2 2 2 1 Multicopper oxidase Alpha_kinase PF02816.18 KIK39333.1 - 0.12 12.5 0.3 0.13 12.4 0.3 1.0 1 0 0 1 1 1 0 Alpha-kinase family DUF155 PF02582.14 KIK39337.1 - 1.1e-54 185.2 0.3 3.7e-54 183.5 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 SesA PF17107.5 KIK39337.1 - 0.095 12.9 0.1 2.7 8.2 0.0 2.5 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DSPc PF00782.20 KIK39338.1 - 8.9e-07 28.8 0.0 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KIK39338.1 - 0.021 14.9 0.0 0.067 13.3 0.0 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 KIK39338.1 - 0.025 14.2 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KIK39338.1 - 0.048 13.6 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF4754 PF15946.5 KIK39339.1 - 0.063 13.6 0.0 19 5.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4754) FA_desaturase PF00487.24 KIK39340.1 - 4.7e-16 59.4 22.2 4.7e-16 59.4 22.2 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KIK39340.1 - 2.8e-13 49.8 0.1 5.1e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Lustrin_cystein PF14625.6 KIK39341.1 - 0.11 12.8 1.3 0.58 10.6 0.1 2.3 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain DUF5425 PF17472.2 KIK39341.1 - 0.14 12.9 2.9 0.21 12.4 2.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5425) DUF3825 PF12873.7 KIK39341.1 - 0.15 11.5 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) G-alpha PF00503.20 KIK39342.1 - 1.3e-119 399.5 0.0 1.5e-119 399.3 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK39342.1 - 1.2e-12 47.6 0.0 1.4e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KIK39342.1 - 0.0004 20.6 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KIK39342.1 - 0.017 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 KIK39342.1 - 0.036 13.8 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain ODR4-like PF14778.6 KIK39342.1 - 0.036 13.0 0.1 0.054 12.4 0.1 1.1 1 0 0 1 1 1 0 Olfactory receptor 4-like AAA_29 PF13555.6 KIK39342.1 - 0.039 13.7 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Peptidase_S10 PF00450.22 KIK39343.1 - 6.9e-116 388.1 0.0 8.5e-116 387.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Acetyltransf_3 PF13302.7 KIK39344.1 - 7.1e-10 39.7 0.0 1.6e-09 38.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK39344.1 - 4.8e-05 23.6 0.0 7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF494 PF04361.13 KIK39344.1 - 0.068 13.1 0.1 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF494) HSP20 PF00011.21 KIK39345.1 - 1.4e-10 41.2 0.0 2.4e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF2046 PF09755.9 KIK39346.1 - 5.5e-12 45.5 10.4 5.5e-12 45.5 10.4 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) ChAPs PF09295.10 KIK39347.1 - 2.1e-147 491.3 0.0 7.3e-146 486.2 0.0 2.0 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 KIK39347.1 - 6.1e-06 26.6 0.3 0.018 15.5 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK39347.1 - 0.00018 21.3 0.1 4.9 7.5 0.0 4.8 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KIK39347.1 - 0.0019 17.5 3.2 1.2 8.3 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK39347.1 - 0.0025 17.9 2.1 0.7 10.3 0.0 4.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK39347.1 - 0.0066 17.2 2.6 2.5 9.2 0.0 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat NARP1 PF12569.8 KIK39347.1 - 0.017 14.0 0.4 0.42 9.5 0.0 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 KIK39347.1 - 0.026 14.2 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain ERCC4 PF02732.15 KIK39348.1 - 7.6e-22 78.2 0.0 1.4e-21 77.3 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain FTCD_C PF04961.12 KIK39348.1 - 0.065 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase WD40 PF00400.32 KIK39349.1 - 1.3e-22 79.6 11.2 3.8e-07 30.7 1.3 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39349.1 - 4.2e-11 43.0 1.1 1.6e-08 34.7 0.6 2.4 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK39349.1 - 3.9e-05 22.5 0.0 0.045 12.4 0.1 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK39349.1 - 0.00061 18.8 0.0 0.012 14.5 0.0 2.1 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK39349.1 - 0.00084 18.8 0.2 0.007 15.7 0.1 1.9 1 1 1 2 2 2 1 Neuroblastoma-amplified sequence, N terminal PQQ PF01011.21 KIK39349.1 - 0.021 14.7 0.1 0.51 10.4 0.2 2.6 3 0 0 3 3 3 0 PQQ enzyme repeat WD40_like PF17005.5 KIK39349.1 - 0.026 13.9 0.0 0.41 9.9 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain RAB3GAP2_N PF14655.6 KIK39349.1 - 0.038 13.2 0.1 0.048 12.9 0.1 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40 PF00400.32 KIK39350.1 - 2e-16 60.0 3.8 2e-08 34.7 0.1 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39350.1 - 5e-07 29.9 0.3 0.18 12.1 0.0 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK39350.1 - 0.0041 15.8 1.3 0.017 13.8 0.5 1.9 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Acetyltransf_3 PF13302.7 KIK39352.1 - 5.7e-18 65.9 0.0 7.5e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK39352.1 - 3.5e-11 43.4 0.0 4.4e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KIK39352.1 - 1.1e-06 28.8 0.0 1.4e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIK39352.1 - 3.2e-05 23.7 0.0 4.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK39352.1 - 5.2e-05 23.6 0.0 8.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK39352.1 - 0.00014 21.8 0.0 0.00023 21.0 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KIK39352.1 - 0.0007 19.5 0.0 0.0011 18.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 KIK39352.1 - 0.13 12.1 0.0 0.34 10.7 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain APS_kinase PF01583.20 KIK39352.1 - 0.18 11.7 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase Pho86 PF11124.8 KIK39353.1 - 0.0026 17.3 0.5 0.0033 16.9 0.5 1.2 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 AMP-binding PF00501.28 KIK39355.1 - 1.4e-79 267.7 0.0 1.7e-79 267.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK39355.1 - 3e-12 47.3 0.6 2.7e-11 44.3 0.1 2.7 3 1 1 4 4 4 1 AMP-binding enzyme C-terminal domain 7TM_GPCR_Srv PF10323.9 KIK39355.1 - 0.099 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv AMP-binding PF00501.28 KIK39356.1 - 3e-83 279.8 0.0 3.8e-83 279.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK39356.1 - 2.7e-12 47.5 0.1 8.7e-12 45.9 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KIK39357.1 - 2.2e-82 276.9 0.1 2.8e-82 276.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK39357.1 - 1.4e-12 48.4 0.2 7.1e-12 46.1 0.2 2.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MHYT PF03707.16 KIK39360.1 - 0.071 13.3 0.1 0.071 13.3 0.1 1.9 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Phage_holin_3_6 PF07332.11 KIK39360.1 - 0.11 12.5 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III MAP17 PF15807.5 KIK39360.1 - 0.13 12.5 0.4 0.29 11.4 0.3 1.6 1 1 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF3328 PF11807.8 KIK39360.1 - 0.19 11.5 0.1 0.91 9.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Mito_carr PF00153.27 KIK39362.1 - 5e-75 247.5 1.6 1.2e-26 92.4 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KIK39362.1 - 1 8.4 3.8 21 4.1 1.0 3.8 2 2 0 2 2 2 0 Gammaproteobacterial serine protease PRiA4_ORF3 PF07929.11 KIK39363.1 - 8.2e-11 41.9 0.1 2.6e-10 40.3 0.1 1.8 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein OSCP PF00213.18 KIK39365.1 - 2.6e-39 135.1 1.6 3e-39 134.9 1.6 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit HA2 PF04408.23 KIK39366.1 - 6e-22 78.0 0.0 6e-22 78.0 0.0 4.5 4 1 0 4 4 4 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KIK39366.1 - 2e-15 57.1 0.0 9.5e-15 54.9 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KIK39366.1 - 2.3e-13 50.3 0.7 6.5e-13 48.8 0.7 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KIK39366.1 - 0.00059 19.6 1.7 0.16 11.7 0.2 3.4 2 1 1 3 3 3 2 DEAD/DEAH box helicase AAA_22 PF13401.6 KIK39366.1 - 0.0015 18.8 0.6 0.018 15.3 0.6 2.7 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KIK39366.1 - 0.011 14.8 0.0 0.027 13.5 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 KIK39366.1 - 0.051 13.3 1.9 0.053 13.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain DUF832 PF05734.11 KIK39366.1 - 0.073 12.5 0.1 0.73 9.3 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus protein of unknown function (DUF832) AAA_19 PF13245.6 KIK39366.1 - 0.28 11.5 3.6 0.2 12.0 0.6 2.2 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 KIK39366.1 - 0.49 10.4 4.3 1.9 8.4 0.2 3.3 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit CwfJ_C_2 PF04676.14 KIK39367.1 - 5.9e-34 116.9 0.9 1.5e-32 112.4 0.0 2.8 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 KIK39367.1 - 2e-30 105.1 0.1 3.2e-30 104.5 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 HpcH_HpaI PF03328.14 KIK39368.1 - 2.9e-41 141.1 0.0 7.2e-41 139.7 0.0 1.6 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KIK39368.1 - 2e-12 46.9 0.0 1.5e-08 34.2 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Abhydrolase_3 PF07859.13 KIK39369.1 - 7.6e-58 195.8 0.0 9.3e-58 195.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK39369.1 - 3.1e-06 26.3 0.0 4.1e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KIK39369.1 - 6e-06 25.4 0.0 2.1e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KIK39369.1 - 0.0012 19.4 0.0 0.002 18.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KIK39369.1 - 0.025 14.1 0.0 0.65 9.4 0.0 2.2 2 1 0 2 2 2 0 Prolyl oligopeptidase family DUF2974 PF11187.8 KIK39369.1 - 0.058 12.9 0.0 0.086 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) eIF-3c_N PF05470.12 KIK39372.1 - 5.7e-184 612.8 23.4 5.7e-184 612.8 23.4 2.8 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KIK39372.1 - 3.1e-16 59.8 0.4 1.1e-14 54.8 0.0 3.0 3 0 0 3 3 3 1 PCI domain T3SS_LEE_assoc PF13327.6 KIK39372.1 - 0.041 13.9 0.2 0.12 12.4 0.2 1.8 1 0 0 1 1 1 0 Type III secretion system subunit rRNA_proc-arch PF13234.6 KIK39373.1 - 2.3e-90 303.2 0.0 3.7e-90 302.5 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KIK39373.1 - 5.4e-52 175.8 0.7 1.2e-51 174.6 0.4 1.7 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 KIK39373.1 - 2.4e-15 56.8 0.2 7e-15 55.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK39373.1 - 1.1e-07 32.1 0.1 1.2e-06 28.8 0.1 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK39373.1 - 0.00055 20.0 0.0 0.0019 18.2 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KIK39373.1 - 0.011 14.8 0.0 0.064 12.3 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 KIK39373.1 - 0.025 14.8 0.1 0.1 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KIK39373.1 - 0.056 13.3 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Dehydratase_SU PF02287.15 KIK39373.1 - 0.1 12.7 0.1 0.66 10.1 0.0 2.2 2 0 0 2 2 2 0 Dehydratase small subunit Catalase PF00199.19 KIK39374.1 - 1.7e-181 603.5 0.0 2.1e-181 603.2 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KIK39374.1 - 4.3e-18 65.3 0.0 1.1e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive RRM_1 PF00076.22 KIK39375.1 - 1.3e-15 56.9 0.0 2.1e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIK39375.1 - 0.0035 16.9 0.0 0.0065 16.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KdpD PF02702.17 KIK39375.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain RRM_7 PF16367.5 KIK39375.1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif zf-C2H2 PF00096.26 KIK39376.1 - 7.5e-07 29.3 5.2 0.00076 19.8 1.2 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK39376.1 - 5.2e-06 26.9 5.1 0.00047 20.8 1.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger MCM_bind PF09739.9 KIK39376.1 - 0.00037 19.1 0.9 0.00046 18.8 0.9 1.1 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor zf-Di19 PF05605.12 KIK39376.1 - 0.0015 18.8 0.6 0.0044 17.3 0.2 2.0 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-TRAF_2 PF15965.5 KIK39376.1 - 0.0034 17.8 1.1 0.0056 17.1 0.6 1.5 1 1 0 1 1 1 1 TRAF-like zinc-finger DTHCT PF08070.11 KIK39376.1 - 0.018 15.8 8.6 0.053 14.3 8.6 1.8 1 0 0 1 1 1 0 DTHCT (NUC029) region zf-met PF12874.7 KIK39376.1 - 0.11 12.9 6.7 2.3 8.7 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-BED PF02892.15 KIK39376.1 - 0.59 10.2 5.2 0.25 11.4 0.9 2.3 1 1 0 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.8 KIK39376.1 - 0.65 10.4 7.8 0.56 10.6 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Myosin_head PF00063.21 KIK39378.1 - 6.8e-254 844.2 0.0 1.6e-253 843.0 0.0 1.7 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KIK39378.1 - 7.3e-22 77.1 223.4 3.3e-10 38.5 90.6 2.2 1 1 1 2 2 2 2 Myosin tail Myosin_N PF02736.19 KIK39378.1 - 2e-11 43.5 0.3 4.1e-11 42.5 0.3 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.21 KIK39378.1 - 0.0047 16.5 16.7 0.0047 16.5 16.7 9.1 2 2 5 8 8 8 3 Intermediate filament protein AAA_22 PF13401.6 KIK39378.1 - 0.027 14.8 0.0 0.027 14.8 0.0 4.0 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 KIK39378.1 - 0.087 12.8 0.0 0.91 9.5 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KIK39378.1 - 1.7 9.0 6.4 1.7 8.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain Ribosomal_L38e PF01781.18 KIK39379.1 - 3.3e-34 116.8 1.2 3.7e-34 116.6 1.2 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Peptidase_M50 PF02163.22 KIK39380.1 - 1.8e-11 43.8 0.3 1e-05 24.9 0.8 3.2 1 1 0 2 2 2 2 Peptidase family M50 DUF1418 PF07214.12 KIK39380.1 - 0.85 9.5 0.0 0.85 9.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) Synaptobrevin PF00957.21 KIK39381.1 - 1.3e-14 53.8 1.2 2.2e-14 53.0 1.2 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KIK39381.1 - 1.9e-12 47.1 0.0 3.5e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Thiolase_N PF00108.23 KIK39382.1 - 1.3e-84 283.6 2.3 1.8e-84 283.2 2.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIK39382.1 - 1.3e-37 128.1 0.6 1.3e-37 128.1 0.6 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIK39382.1 - 0.0037 16.9 3.1 0.037 13.6 2.2 2.4 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KIK39382.1 - 0.018 14.9 1.2 0.66 9.9 0.0 3.2 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Glyco_hydro_16 PF00722.21 KIK39384.1 - 2.9e-15 56.2 0.2 1.6e-14 53.8 0.2 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SSP160 PF06933.11 KIK39384.1 - 0.25 9.5 21.6 0.45 8.7 21.6 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SWI-SNF_Ssr4 PF08549.10 KIK39384.1 - 0.36 9.4 2.7 0.5 8.9 2.7 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Glyco_trans_2_3 PF13632.6 KIK39385.1 - 1.5e-54 184.9 1.0 1.5e-54 184.9 1.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KIK39385.1 - 5e-05 23.3 0.1 9.4e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIK39385.1 - 0.041 13.7 0.0 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 DIM PF08194.12 KIK39389.1 - 0.063 13.5 0.0 0.075 13.3 0.0 1.1 1 0 0 1 1 1 0 DIM protein FAD_binding_4 PF01565.23 KIK39391.1 - 1.8e-19 69.9 2.4 2.6e-19 69.3 2.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK39391.1 - 4.5e-07 29.9 0.0 1.3e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like WD40 PF00400.32 KIK39392.1 - 8.4e-38 127.7 13.8 4e-08 33.8 0.3 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39392.1 - 7.3e-18 64.7 0.1 0.00034 20.9 0.0 5.2 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK39392.1 - 7.6e-06 25.1 0.0 1.7 7.5 0.0 4.3 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK39392.1 - 9.9e-05 21.8 0.2 7.3 5.8 0.0 4.1 2 1 2 4 4 4 3 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK39392.1 - 0.00063 18.5 0.0 0.34 9.5 0.1 2.6 2 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK39392.1 - 0.00091 19.2 0.0 0.018 15.0 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 KIK39392.1 - 0.0079 15.8 0.0 0.067 12.8 0.0 2.3 1 1 1 2 2 2 1 PQQ-like domain PD40 PF07676.12 KIK39392.1 - 0.13 12.2 0.8 17 5.5 0.1 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat FAD_binding_4 PF01565.23 KIK39393.1 - 8.1e-20 71.0 2.6 1.3e-19 70.3 2.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK39393.1 - 9.2e-07 28.9 0.0 2.8e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like ATP19 PF11022.8 KIK39397.1 - 9.6e-25 86.8 0.2 1.4e-24 86.2 0.2 1.2 1 0 0 1 1 1 1 ATP synthase subunit K DUF2034 PF10356.9 KIK39398.1 - 1.2e-21 77.0 0.1 1.4e-11 44.2 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KIK39398.1 - 0.00043 20.3 0.0 0.00071 19.6 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease WW PF00397.26 KIK39399.1 - 4.9e-05 23.3 0.3 7.7e-05 22.7 0.3 1.3 1 0 0 1 1 1 1 WW domain WD40 PF00400.32 KIK39400.1 - 6.9e-34 115.3 15.9 1e-08 35.6 0.7 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39400.1 - 1.9e-10 40.9 0.5 5e-05 23.5 0.2 3.8 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK39400.1 - 0.00011 21.0 1.4 0.4 9.3 0.1 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK39400.1 - 0.00016 21.7 0.1 0.0017 18.3 0.0 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KIK39400.1 - 0.01 14.6 0.6 0.075 11.8 0.2 2.6 2 1 0 2 2 2 0 Nup133 N terminal like Ge1_WD40 PF16529.5 KIK39400.1 - 0.02 13.9 0.0 2.3 7.1 0.0 3.1 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PA14 PF07691.12 KIK39400.1 - 0.03 14.1 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 PA14 domain WD40_like PF17005.5 KIK39400.1 - 0.12 11.7 0.0 1.5 8.1 0.0 2.1 1 1 1 2 2 2 0 WD40-like domain PD40 PF07676.12 KIK39400.1 - 0.12 12.3 0.6 35 4.5 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 KIK39401.1 - 2.4e-36 123.1 12.1 7.4e-08 32.9 0.2 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39401.1 - 9.3e-10 38.7 0.1 0.0001 22.5 0.0 3.5 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WW PF00397.26 KIK39401.1 - 1.2e-06 28.4 2.4 5.5e-06 26.4 2.4 2.2 1 0 0 1 1 1 1 WW domain ChuX_HutX PF06228.13 KIK39401.1 - 0.017 14.9 0.0 3.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Haem utilisation ChuX/HutX Ge1_WD40 PF16529.5 KIK39401.1 - 0.045 12.7 0.0 0.64 8.9 0.0 2.7 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK39401.1 - 0.054 13.4 0.2 5.8 7.0 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF3915 PF13054.6 KIK39405.1 - 3 7.8 5.5 5.5 7.0 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) IBR PF01485.21 KIK39406.1 - 8.2e-14 51.6 34.3 7.5e-08 32.5 7.2 4.3 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain zf-CCCH_3 PF15663.5 KIK39406.1 - 6.6e-10 39.2 10.2 7.9e-05 22.8 3.2 2.6 2 0 0 2 2 2 2 Zinc-finger containing family zf-C3HC4 PF00097.25 KIK39406.1 - 3.9e-06 26.6 4.2 3.9e-06 26.6 4.2 3.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK39406.1 - 1.8e-05 24.7 5.5 1.8e-05 24.7 5.5 3.1 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIK39406.1 - 0.00014 21.6 2.1 0.00014 21.6 2.1 3.7 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KIK39406.1 - 0.0005 19.8 0.0 0.79 9.6 0.0 3.8 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 KIK39406.1 - 0.00063 19.6 3.0 0.00063 19.6 3.0 4.8 4 1 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK39406.1 - 0.00069 19.7 5.6 0.00069 19.7 5.6 3.6 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING Torus PF16131.5 KIK39406.1 - 0.0022 18.7 10.2 0.18 12.5 0.9 3.3 2 1 1 3 3 3 2 Torus domain zf-RING_5 PF14634.6 KIK39406.1 - 0.005 16.8 4.5 0.005 16.8 4.5 3.4 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KIK39406.1 - 0.013 15.8 4.3 0.013 15.8 4.3 4.3 3 1 1 4 4 2 0 Ring finger domain zf-CCCH PF00642.24 KIK39406.1 - 0.017 15.0 24.0 0.61 10.1 5.8 3.7 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_6 PF13912.6 KIK39406.1 - 0.018 15.1 0.1 0.018 15.1 0.1 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger RRM_occluded PF16842.5 KIK39406.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif zf_CCCH_4 PF18345.1 KIK39406.1 - 0.2 11.7 24.9 1.6 8.8 8.1 4.6 3 2 0 3 3 3 0 Zinc finger domain Tht1 PF04163.12 KIK39408.1 - 7.1e-13 48.2 0.1 1.2e-12 47.4 0.1 1.4 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein MAD PF05557.13 KIK39409.1 - 0.026 12.9 0.4 0.033 12.6 0.4 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF2630 PF10944.8 KIK39409.1 - 0.12 12.8 1.5 0.22 12.0 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) Pox_A_type_inc PF04508.12 KIK39409.1 - 0.13 12.2 3.1 0.56 10.2 0.2 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Mitochondr_Som1 PF11093.8 KIK39411.1 - 4.8e-09 36.1 0.2 6.2e-09 35.7 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 AdoHcyase PF05221.17 KIK39412.1 - 3.1e-133 443.5 0.0 2.3e-73 247.0 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KIK39412.1 - 2.1e-84 281.5 0.8 3.2e-84 280.9 0.8 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KIK39412.1 - 1e-07 31.5 0.0 2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KIK39412.1 - 0.00014 21.5 0.1 0.00025 20.7 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KIK39412.1 - 0.0012 19.0 0.0 0.0027 18.0 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 KIK39412.1 - 0.11 13.0 0.1 0.29 11.6 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding F420_oxidored PF03807.17 KIK39412.1 - 0.12 13.0 0.1 0.28 11.8 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pro_CA PF00484.19 KIK39413.1 - 7.9e-42 143.2 0.3 9.7e-42 142.9 0.3 1.1 1 0 0 1 1 1 1 Carbonic anhydrase DUF436 PF04260.12 KIK39413.1 - 0.075 12.6 0.7 2.6 7.6 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF436) Glyco_hydro_25 PF01183.20 KIK39414.1 - 1.6e-44 152.3 4.1 1.9e-44 152.0 4.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 ThiF PF00899.21 KIK39415.1 - 3.2e-104 347.6 0.0 5.1e-69 232.3 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KIK39415.1 - 4.8e-89 298.6 0.0 7.8e-89 297.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 KIK39415.1 - 4.4e-33 113.3 0.1 8.8e-33 112.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 KIK39415.1 - 1.9e-30 105.4 1.5 4.5e-30 104.2 1.5 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 KIK39415.1 - 2.4e-25 88.5 2.0 5.9e-25 87.2 1.1 2.2 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle Cyclin PF08613.11 KIK39416.1 - 0.00043 20.7 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 Cyclin DUF3402 PF11882.8 KIK39417.1 - 9.5e-121 404.1 0.1 1.8e-118 396.6 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KIK39417.1 - 5.5e-75 252.2 0.0 8.9e-75 251.5 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein GIIM PF08388.11 KIK39417.1 - 0.2 11.8 0.6 4.6 7.4 0.2 2.7 2 0 0 2 2 2 0 Group II intron, maturase-specific domain WD40 PF00400.32 KIK39418.1 - 1.3e-25 89.2 10.2 9e-08 32.7 0.6 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39418.1 - 3.6e-09 36.8 0.2 0.038 14.3 0.1 3.3 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK39418.1 - 0.0029 16.3 2.2 0.011 14.4 1.6 1.9 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK39418.1 - 0.068 12.1 0.9 15 4.4 0.1 3.1 1 1 3 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Diphthamide_syn PF01866.17 KIK39420.1 - 8.6e-94 314.4 0.0 3.7e-55 187.5 0.0 2.8 2 1 0 2 2 2 2 Putative diphthamide synthesis protein NPC1_N PF16414.5 KIK39421.1 - 3e-81 272.6 7.1 3e-81 272.6 7.1 1.5 2 0 0 2 2 2 1 Niemann-Pick C1 N terminus Patched PF02460.18 KIK39421.1 - 2.9e-72 244.0 1.3 4.5e-37 127.6 0.0 3.1 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.8 KIK39421.1 - 1.6e-45 154.7 12.7 5.2e-24 84.8 0.1 3.8 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 KIK39421.1 - 6e-09 34.2 6.0 6e-09 34.2 6.0 2.1 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family Folate_rec PF03024.14 KIK39421.1 - 0.0021 18.0 0.4 0.0042 17.0 0.4 1.4 1 0 0 1 1 1 1 Folate receptor family RRM_1 PF00076.22 KIK39422.1 - 4.3e-12 45.7 0.0 5.1e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIK39422.1 - 1.3e-08 34.5 0.0 1.6e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIK39422.1 - 0.019 14.8 0.1 0.034 14.0 0.1 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KIK39422.1 - 0.094 12.7 0.0 0.15 12.1 0.0 1.3 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-H2C2_2 PF13465.6 KIK39424.1 - 7.9e-07 29.2 2.7 7.9e-07 29.2 2.7 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 KIK39424.1 - 3.9e-06 27.0 2.5 3.9e-06 27.0 2.5 1.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK39424.1 - 0.00034 21.2 6.8 0.00045 20.8 1.9 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger FYVE PF01363.21 KIK39424.1 - 0.067 13.3 1.8 0.074 13.2 1.8 1.2 1 0 0 1 1 1 0 FYVE zinc finger zf-met PF12874.7 KIK39424.1 - 0.089 13.2 0.2 0.089 13.2 0.2 1.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FAD_binding_6 PF00970.24 KIK39425.1 - 1.4e-11 44.6 0.0 3.2e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KIK39425.1 - 2.8e-11 44.0 0.0 8.1e-11 42.5 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KIK39425.1 - 7e-07 29.5 0.0 1.5e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KIK39425.1 - 0.067 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Med18 PF09637.10 KIK39426.1 - 4.1e-06 26.8 0.0 4.5e-05 23.4 0.0 1.9 1 1 1 2 2 2 2 Med18 protein zf-HIT PF04438.16 KIK39427.1 - 8.5e-07 28.7 15.7 1.5e-06 27.9 15.7 1.4 1 0 0 1 1 1 1 HIT zinc finger FoP_duplication PF13865.6 KIK39427.1 - 0.025 15.1 4.8 0.073 13.6 4.8 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Pkinase_fungal PF17667.1 KIK39429.1 - 5.4e-29 101.2 0.0 4.7e-18 65.2 0.4 2.0 1 1 1 2 2 2 2 Fungal protein kinase CIAPIN1 PF05093.13 KIK39430.1 - 8.3e-31 106.5 2.2 1.3e-30 105.9 2.2 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KIK39430.1 - 5.4e-08 33.2 0.0 7.8e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Forkhead PF00250.18 KIK39431.1 - 6.8e-31 106.4 0.0 1.1e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain CHAT PF12770.7 KIK39432.1 - 5.4e-21 75.2 0.0 6.2e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 CHAT domain Surp PF01805.20 KIK39432.1 - 0.024 14.6 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Surp module CCDC92 PF14916.6 KIK39432.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain of unknown function AAA_16 PF13191.6 KIK39433.1 - 0.013 15.9 0.0 0.013 15.9 0.0 1.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KIK39433.1 - 0.085 13.1 0.1 0.13 12.6 0.0 1.3 1 1 0 1 1 1 0 AAA domain CPL PF08144.11 KIK39435.1 - 6.2e-34 117.4 0.1 6.6e-32 110.8 0.0 3.4 3 1 1 4 4 4 1 CPL (NUC119) domain UpxZ PF06603.11 KIK39435.1 - 0.044 14.1 0.2 21 5.5 0.0 3.7 3 1 1 4 4 4 0 UpxZ family of transcription anti-terminator antagonists F-box-like PF12937.7 KIK39439.1 - 2.3e-06 27.4 1.3 1e-05 25.3 0.2 2.6 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIK39439.1 - 0.02 15.3 6.5 7.5 7.1 0.0 6.2 5 4 3 8 8 8 0 Leucine Rich repeats (2 copies) CybS PF05328.12 KIK39442.1 - 5.6e-45 152.3 0.0 7.1e-45 152.0 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit DUF4329 PF14220.6 KIK39443.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4329) ThiF PF00899.21 KIK39444.1 - 4.7e-73 245.5 0.0 6.9e-73 245.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 KIK39444.1 - 9.6e-14 51.9 0.1 3.6e-12 46.8 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 KIK39444.1 - 1.1e-07 32.4 0.0 2.5e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 KIK39444.1 - 0.00052 20.4 0.0 0.0017 18.7 0.0 1.9 1 1 0 1 1 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KIK39444.1 - 0.052 13.8 1.2 0.1 12.9 0.1 2.0 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KIK39444.1 - 0.058 13.4 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.23 KIK39444.1 - 0.13 12.3 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_6 PF08030.12 KIK39445.1 - 2.2e-05 24.7 0.0 3.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Putative_PNPOx PF01243.20 KIK39445.1 - 0.00079 19.6 0.0 0.045 13.9 0.0 2.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.21 KIK39445.1 - 0.09 13.4 0.0 0.22 12.2 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain GST_C_2 PF13410.6 KIK39446.1 - 5.5e-10 39.1 0.0 8.3e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK39446.1 - 5.7e-09 36.1 0.0 9.9e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIK39446.1 - 1.5e-07 31.7 0.0 2.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK39446.1 - 2.3e-06 27.7 0.0 3.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 KIK39446.1 - 1.2e-05 25.1 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_N_2 PF13409.6 KIK39446.1 - 0.00043 20.5 0.0 0.00081 19.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK39446.1 - 0.00049 20.4 0.0 0.00081 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KIK39446.1 - 0.12 12.2 0.0 0.6 9.9 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF1236 PF06823.12 KIK39447.1 - 0.021 14.7 1.8 1.2 9.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1236) YqcI_YcgG PF08892.11 KIK39448.1 - 5.9e-63 212.5 0.0 7.7e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 YqcI/YcgG family TMIE PF16038.5 KIK39450.1 - 0.1 12.4 4.2 0.19 11.6 4.2 1.4 1 1 0 1 1 1 0 TMIE protein adh_short PF00106.25 KIK39451.1 - 1e-42 145.9 0.0 1.3e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK39451.1 - 1.6e-29 103.1 0.0 2e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK39451.1 - 2.4e-10 40.6 0.0 4.2e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KIK39451.1 - 1.5e-05 25.0 0.0 2.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIK39451.1 - 0.00042 19.9 0.0 0.00067 19.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KIK39451.1 - 0.073 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family BChl_A PF02327.17 KIK39451.1 - 0.075 11.8 0.1 0.12 11.2 0.1 1.3 1 0 0 1 1 1 0 Bacteriochlorophyll A protein Sacchrp_dh_NADP PF03435.18 KIK39451.1 - 0.18 12.0 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Catalase PF00199.19 KIK39454.1 - 3.8e-150 500.3 0.0 5e-150 499.9 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KIK39454.1 - 4.9e-12 45.9 0.0 2.1e-11 43.9 0.0 2.1 1 0 0 1 1 1 1 Catalase-related immune-responsive CDC4_D PF16856.5 KIK39454.1 - 0.12 12.3 0.1 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 Cell division control protein 4 dimerisation domain JSRP PF15312.6 KIK39457.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein NAD_binding_1 PF00175.21 KIK39458.1 - 0.0002 22.0 0.0 0.00036 21.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Putative_PNPOx PF01243.20 KIK39458.1 - 0.00059 20.0 0.0 1.8 8.8 0.0 2.9 2 1 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_6 PF08030.12 KIK39458.1 - 0.016 15.3 0.2 0.086 13.0 0.0 2.0 1 1 0 2 2 2 0 Ferric reductase NAD binding domain zf-C2H2 PF00096.26 KIK39459.1 - 0.023 15.1 0.1 0.023 15.1 0.1 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type RNA_pol_N PF01194.17 KIK39459.1 - 0.025 14.8 0.2 0.069 13.5 0.2 1.7 1 0 0 1 1 1 0 RNA polymerases N / 8 kDa subunit zf-C2H2_4 PF13894.6 KIK39459.1 - 0.028 15.2 12.5 0.078 13.9 0.0 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf_UBZ PF18439.1 KIK39459.1 - 0.034 13.8 0.0 0.12 12.0 0.0 2.0 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger EMP24_GP25L PF01105.24 KIK39459.1 - 0.1 12.6 0.4 0.17 11.8 0.1 1.5 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Ribosomal_L13e PF01294.18 KIK39459.1 - 0.18 11.6 0.6 0.29 11.0 0.6 1.3 1 0 0 1 1 1 0 Ribosomal protein L13e zf_C2H2_ZHX PF18387.1 KIK39459.1 - 0.22 11.2 7.5 0.28 10.8 0.3 3.2 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-BED PF02892.15 KIK39459.1 - 0.6 10.2 6.5 4.9 7.3 1.2 3.0 3 0 0 3 3 3 0 BED zinc finger DUF4603 PF15376.6 KIK39460.1 - 0.022 12.2 1.5 0.027 11.9 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) SAP18 PF06487.12 KIK39461.1 - 8.4e-38 129.7 0.0 1e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) DUF1768 PF08719.11 KIK39462.1 - 1.5e-23 83.8 0.0 2.1e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Pkinase_Tyr PF07714.17 KIK39463.1 - 1.4e-26 93.4 0.0 2e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK39463.1 - 2.1e-23 83.0 0.0 3.6e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RRM_3 PF08777.11 KIK39464.1 - 6.7e-06 26.1 0.0 1.7e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 RNA binding motif P33MONOX PF15302.6 KIK39464.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 P33 mono-oxygenase RRM_1 PF00076.22 KIK39464.1 - 0.19 11.5 0.2 1.6 8.6 0.0 2.6 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GerD PF17898.1 KIK39465.1 - 0.0046 16.9 0.1 0.0088 16.0 0.1 1.4 1 0 0 1 1 1 1 Spore germination GerD central core domain CsgA PF17334.2 KIK39465.1 - 0.11 13.2 0.3 0.23 12.2 0.3 1.4 1 0 0 1 1 1 0 Minor curli fiber component A ATG22 PF11700.8 KIK39466.1 - 2.5e-114 382.5 20.6 2.9e-114 382.4 20.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KIK39466.1 - 1.6e-13 50.3 31.8 5.3e-08 32.2 9.5 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.8 KIK39467.1 - 9.9e-109 364.1 22.8 1.1e-108 363.9 22.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KIK39467.1 - 6.1e-13 48.4 33.8 8.2e-07 28.3 10.5 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily WD40 PF00400.32 KIK39468.1 - 4.1e-29 100.2 10.2 1.4e-05 25.8 0.0 7.9 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39468.1 - 1.7e-13 50.7 0.0 9.1e-05 22.7 0.0 4.0 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK39468.1 - 0.011 15.0 0.0 2.1 7.6 0.0 2.8 3 0 0 3 3 3 0 WD40-like domain Frtz PF11768.8 KIK39468.1 - 0.049 11.9 0.0 0.42 8.9 0.0 2.0 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 KIK39468.1 - 0.59 10.7 6.6 1.7 9.2 0.1 4.0 3 2 1 4 4 4 0 PQQ-like domain DUF4407 PF14362.6 KIK39469.1 - 0.15 11.3 9.6 0.018 14.4 4.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DivIC PF04977.15 KIK39469.1 - 0.64 9.8 17.7 0.56 10.0 1.9 3.6 2 1 1 3 3 3 0 Septum formation initiator Spc7 PF08317.11 KIK39469.1 - 7.2 5.4 14.3 0.74 8.6 8.4 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein CENP-H PF05837.12 KIK39469.1 - 8.6 6.8 22.3 0.059 13.8 7.2 3.4 3 1 0 3 3 3 0 Centromere protein H (CENP-H) AAA PF00004.29 KIK39470.1 - 2.8e-07 31.0 0.0 9.3e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK39470.1 - 9.2e-05 22.9 0.0 0.00024 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK39470.1 - 0.0026 18.0 0.0 0.0073 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK39470.1 - 0.0041 17.5 3.0 0.012 16.0 0.1 2.7 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 KIK39470.1 - 0.019 14.9 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KIK39470.1 - 0.022 14.0 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_30 PF13604.6 KIK39470.1 - 0.025 14.3 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK39470.1 - 0.032 14.8 0.0 0.16 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KIK39470.1 - 0.04 13.4 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KIK39470.1 - 0.04 13.9 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 KIK39470.1 - 0.044 12.8 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 KIK39470.1 - 0.052 13.5 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SRP54 PF00448.22 KIK39470.1 - 0.077 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 KIK39470.1 - 0.083 13.4 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIK39470.1 - 0.097 12.6 0.0 0.21 11.5 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Torsin PF06309.11 KIK39470.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_PrkA PF08298.11 KIK39470.1 - 0.16 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain AAA_11 PF13086.6 KIK39470.1 - 0.18 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.22 KIK39471.1 - 9.2e-21 73.5 0.1 2.5e-11 43.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KIK39471.1 - 0.017 14.9 0.0 6.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 KIK39471.1 - 0.032 14.2 0.0 0.069 13.2 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ofd1_CTDD PF10637.9 KIK39472.1 - 3.4e-80 269.1 0.0 1.6e-77 260.3 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KIK39472.1 - 5.7e-32 110.2 0.0 1.9e-31 108.6 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KIK39472.1 - 7.7e-16 58.8 0.3 4.1e-15 56.5 0.0 2.3 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily NOA36 PF06524.12 KIK39472.1 - 6.6 6.0 7.1 11 5.2 7.1 1.2 1 0 0 1 1 1 0 NOA36 protein F-box-like PF12937.7 KIK39473.1 - 1.7e-09 37.4 0.1 3.3e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like AAA PF00004.29 KIK39475.1 - 7e-19 68.6 0.0 1.3e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK39475.1 - 5.7e-05 23.6 0.5 0.00018 21.9 0.5 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK39475.1 - 7e-05 23.1 0.8 0.0018 18.6 0.8 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KIK39475.1 - 0.00042 20.1 0.1 0.0008 19.2 0.1 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KIK39475.1 - 0.00087 19.5 0.0 0.0021 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KIK39475.1 - 0.0016 18.4 0.0 0.0048 16.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KIK39475.1 - 0.0017 18.1 0.3 0.0059 16.3 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK39475.1 - 0.0093 15.8 0.1 0.025 14.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 KIK39475.1 - 0.026 14.5 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KIK39475.1 - 0.03 14.9 0.0 0.28 11.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KIK39475.1 - 0.045 13.2 0.2 0.2 11.1 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_2 PF07724.14 KIK39475.1 - 0.056 13.6 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_19 PF13245.6 KIK39475.1 - 0.061 13.7 0.1 0.22 11.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIK39475.1 - 0.086 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KIK39475.1 - 0.15 11.4 0.0 0.39 10.1 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MeaB PF03308.16 KIK39475.1 - 0.35 9.8 1.1 0.42 9.5 0.1 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CDC14 PF08045.11 KIK39476.1 - 2.9e-29 102.1 0.5 8.9e-19 67.7 0.0 3.1 3 0 0 3 3 3 3 Cell division control protein 14, SIN component CDC14 PF08045.11 KIK39477.1 - 0.0052 15.9 0.1 0.0055 15.8 0.1 1.1 1 0 0 1 1 1 1 Cell division control protein 14, SIN component TPR_7 PF13176.6 KIK39477.1 - 0.0073 16.3 0.3 0.046 13.7 0.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat Dak1 PF02733.17 KIK39477.1 - 0.12 11.2 0.0 0.14 11.0 0.0 1.0 1 0 0 1 1 1 0 Dak1 domain FAA_hydrolase PF01557.18 KIK39478.1 - 2.9e-57 193.9 0.0 3.6e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GspH PF12019.8 KIK39478.1 - 0.12 12.8 0.3 0.2 12.1 0.3 1.4 1 0 0 1 1 1 0 Type II transport protein GspH Aldedh PF00171.22 KIK39479.1 - 2.1e-159 531.0 3.6 2.3e-159 530.8 3.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family F-box-like PF12937.7 KIK39480.1 - 1.1e-08 34.8 0.3 2.7e-08 33.6 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK39480.1 - 0.0003 20.6 0.2 0.0007 19.4 0.2 1.5 1 0 0 1 1 1 1 F-box domain CDP-OH_P_transf PF01066.21 KIK39481.1 - 3.5e-18 66.1 0.0 3.5e-18 66.1 0.0 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase tRNA-synt_His PF13393.6 KIK39483.1 - 3.4e-38 131.6 1.2 1e-33 116.9 0.0 2.8 3 0 0 3 3 3 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KIK39483.1 - 4.3e-10 39.6 0.2 9.1e-10 38.6 0.2 1.5 1 0 0 1 1 1 1 Anticodon binding domain Erythro-docking PF09277.11 KIK39483.1 - 0.022 14.7 0.2 0.08 12.9 0.1 2.0 2 0 0 2 2 2 0 Erythronolide synthase, docking tRNA-synt_2d PF01409.20 KIK39483.1 - 0.09 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) RRM_1 PF00076.22 KIK39484.1 - 1.1e-18 66.8 0.0 1.5e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIK39484.1 - 0.19 11.3 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mating_C PF12737.7 KIK39486.1 - 0.15 11.2 6.8 0.23 10.7 6.8 1.2 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Herpes_DNAp_acc PF04929.12 KIK39486.1 - 2 7.3 6.7 3 6.7 6.7 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor CHAT PF12770.7 KIK39487.1 - 1e-41 143.3 0.4 2.2e-41 142.2 0.4 1.5 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK39487.1 - 2.5e-27 93.9 22.2 0.0014 18.5 0.1 11.3 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_12 PF13424.6 KIK39487.1 - 1.8e-07 31.3 27.7 2.7 8.3 0.3 10.5 6 4 4 10 10 10 4 Tetratricopeptide repeat GATase_4 PF13230.6 KIK39487.1 - 2.7e-07 29.8 0.4 0.32 9.9 0.1 4.6 3 1 1 5 5 5 3 Glutamine amidotransferases class-II TPR_7 PF13176.6 KIK39487.1 - 1.2e-06 28.1 7.0 0.21 11.7 0.0 8.0 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK39487.1 - 2.8e-05 24.0 1.1 1.1e+02 3.4 0.0 7.5 8 0 0 8 8 7 0 Tetratricopeptide repeat DUF4471 PF14740.6 KIK39487.1 - 0.00017 20.9 0.0 5.4 6.2 0.0 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF4471) T3SS_ATPase_C PF18269.1 KIK39487.1 - 0.0018 18.1 9.0 18 5.3 0.0 6.8 8 0 0 8 8 8 0 T3SS EscN ATPase C-terminal domain HTH_27 PF13463.6 KIK39487.1 - 0.028 14.9 0.1 36 4.9 0.0 5.1 5 0 0 5 5 5 0 Winged helix DNA-binding domain TPR_11 PF13414.6 KIK39487.1 - 0.32 10.7 14.1 4 7.2 0.0 6.5 8 0 0 8 8 8 0 TPR repeat TPR_14 PF13428.6 KIK39487.1 - 0.47 11.4 23.5 5.7 8.0 0.2 9.3 11 1 1 12 12 9 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK39487.1 - 0.91 9.8 25.2 45 4.5 0.1 8.8 9 0 0 9 9 9 0 Tetratricopeptide repeat DUF1115 PF06544.12 KIK39489.1 - 2e-07 31.2 0.1 2.9e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.22 KIK39489.1 - 0.052 13.8 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain Acylphosphatase PF00708.18 KIK39489.1 - 0.11 13.0 0.0 0.3 11.5 0.0 1.8 1 1 1 2 2 2 0 Acylphosphatase YHYH PF14240.6 KIK39489.1 - 0.19 11.6 0.0 0.29 11.1 0.0 1.2 1 0 0 1 1 1 0 YHYH protein WD40 PF00400.32 KIK39490.1 - 2.1e-14 53.7 11.4 7.4e-05 23.4 0.1 5.7 7 0 0 7 7 7 4 WD domain, G-beta repeat PD40 PF07676.12 KIK39490.1 - 3e-06 27.0 1.2 3.2 7.8 0.0 5.0 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 KIK39490.1 - 1.2e-05 25.6 0.0 0.72 10.2 0.0 4.1 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 KIK39490.1 - 0.0023 16.0 0.1 0.026 12.5 0.0 2.0 1 1 1 2 2 2 2 IKI3 family eIF2A PF08662.11 KIK39490.1 - 0.0074 16.2 0.0 1.7 8.5 0.0 2.6 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A B_lectin PF01453.24 KIK39490.1 - 0.012 16.2 0.1 0.026 15.0 0.1 1.5 1 0 0 1 1 1 0 D-mannose binding lectin Proteasome_A_N PF10584.9 KIK39490.1 - 0.11 12.2 2.1 82 3.0 0.2 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature TFIIIC_delta PF12657.7 KIK39490.1 - 0.48 10.3 3.2 14 5.6 0.1 3.8 4 1 1 5 5 5 0 Transcription factor IIIC subunit delta N-term ubiquitin PF00240.23 KIK39492.1 - 3.8e-18 65.0 0.5 6.4e-18 64.3 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KIK39492.1 - 5.8e-11 42.1 0.1 1.3e-10 41.0 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 KIK39492.1 - 3.5e-09 36.4 1.0 6e-09 35.6 1.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KIK39492.1 - 1.2e-05 25.8 0.1 2.1e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KIK39492.1 - 0.019 15.0 0.8 0.36 10.9 0.2 2.3 1 1 1 2 2 2 0 Ubiquitin-like domain TBK1_ULD PF18396.1 KIK39492.1 - 0.028 14.4 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIK39492.1 - 0.059 13.5 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like GerD PF17898.1 KIK39492.1 - 0.08 12.9 2.4 0.18 11.8 2.4 1.5 1 1 0 1 1 1 0 Spore germination GerD central core domain Ubiquitin_5 PF18037.1 KIK39492.1 - 0.16 12.4 0.1 0.26 11.7 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain STI1 PF17830.1 KIK39492.1 - 0.88 9.6 13.7 1.1 9.3 6.9 3.3 2 1 0 3 3 3 0 STI1 domain Dus PF01207.17 KIK39493.1 - 2.4e-72 243.6 0.0 3.3e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.17 KIK39493.1 - 5.6e-05 23.0 0.0 0.0056 16.5 0.0 2.4 1 1 1 2 2 2 2 SOR/SNZ family ThiG PF05690.14 KIK39493.1 - 0.00051 19.4 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG NMO PF03060.15 KIK39493.1 - 0.0038 16.7 0.0 0.027 13.8 0.0 2.0 1 1 1 2 2 2 1 Nitronate monooxygenase TMP-TENI PF02581.17 KIK39493.1 - 0.097 12.0 0.1 0.19 11.0 0.1 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase Glyco_hydro_28 PF00295.17 KIK39496.1 - 4.1e-40 137.8 4.5 6.7e-40 137.1 4.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KIK39496.1 - 0.0077 16.1 7.9 0.0077 16.1 7.9 3.1 2 1 1 3 3 3 1 Right handed beta helix region Histone PF00125.24 KIK39497.1 - 1.5e-49 167.7 3.9 1.6e-49 167.6 3.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KIK39497.1 - 2.6e-05 24.5 0.1 4.2e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KIK39497.1 - 9.4e-05 22.5 1.2 0.0001 22.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KIK39497.1 - 0.0014 18.8 0.1 0.0014 18.8 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 KIK39497.1 - 0.0024 18.4 2.2 0.0032 18.1 2.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Bromo_TP PF07524.13 KIK39497.1 - 0.084 12.9 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 KIK39497.1 - 0.12 12.5 0.4 0.17 11.9 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit DUF726 PF05277.12 KIK39499.1 - 2.3e-119 398.3 1.5 3.3e-119 397.8 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_1 PF00561.20 KIK39499.1 - 0.033 13.8 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Phage_TAC_7 PF10109.9 KIK39499.1 - 0.066 13.3 0.5 0.14 12.3 0.5 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone proteins, E, or 41 or 14 SRP14 PF02290.15 KIK39500.1 - 3.5e-22 78.6 0.9 5.8e-22 77.9 0.0 1.8 2 1 0 2 2 2 1 Signal recognition particle 14kD protein AAA_33 PF13671.6 KIK39500.1 - 0.006 16.7 1.7 0.013 15.7 1.7 1.6 1 1 0 1 1 1 1 AAA domain DUF3959 PF13105.6 KIK39500.1 - 8.5 5.8 6.3 11 5.5 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Peptidase_U4 PF03419.13 KIK39504.1 - 3.2 7.0 18.9 1.2 8.4 16.2 1.6 1 1 0 1 1 1 0 Sporulation factor SpoIIGA zf-MYND PF01753.18 KIK39505.1 - 2.8e-11 43.3 18.0 4.6e-11 42.6 18.0 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIK39505.1 - 0.017 15.4 13.4 0.041 14.2 13.4 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF1360 PF07098.11 KIK39505.1 - 0.035 14.0 0.5 0.069 13.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) PolC_DP2 PF03833.13 KIK39505.1 - 0.078 10.8 1.0 0.099 10.5 1.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Rhodanese_C PF12368.8 KIK39505.1 - 1.3 9.4 7.7 2.7 8.4 7.7 1.4 1 0 0 1 1 1 0 Rhodanase C-terminal zinc_ribbon_5 PF13719.6 KIK39505.1 - 1.8 8.4 8.3 36 4.2 8.3 2.3 1 1 0 1 1 1 0 zinc-ribbon domain GMC_oxred_C PF05199.13 KIK39506.1 - 1.5e-11 45.0 0.0 2.8e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Thyroglobulin_1 PF00086.18 KIK39509.1 - 0.062 13.0 0.1 0.093 12.4 0.1 1.4 1 0 0 1 1 1 0 Thyroglobulin type-1 repeat TPR_2 PF07719.17 KIK39510.1 - 0.0035 17.3 0.0 2.3 8.5 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KIK39510.1 - 0.0077 16.1 0.1 0.12 12.3 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIK39510.1 - 0.017 15.4 0.2 2.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK39510.1 - 0.048 14.5 0.0 5.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK39510.1 - 0.055 13.7 0.0 5.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-MYND PF01753.18 KIK39512.1 - 1.1e-09 38.2 15.6 1.6e-09 37.7 15.6 1.2 1 0 0 1 1 1 1 MYND finger DUF1360 PF07098.11 KIK39512.1 - 0.095 12.7 0.7 0.11 12.4 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) zinc_ribbon_5 PF13719.6 KIK39512.1 - 0.12 12.2 7.0 0.43 10.4 1.8 2.5 1 1 1 2 2 2 0 zinc-ribbon domain zf-HIT PF04438.16 KIK39512.1 - 0.13 12.1 9.2 0.19 11.6 9.2 1.3 1 0 0 1 1 1 0 HIT zinc finger PolC_DP2 PF03833.13 KIK39512.1 - 0.47 8.2 2.8 0.43 8.4 2.8 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-MYND PF01753.18 KIK39514.1 - 2.3e-10 40.4 17.0 4.2e-10 39.5 17.0 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIK39514.1 - 0.12 12.7 16.4 0.25 11.7 16.4 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PolC_DP2 PF03833.13 KIK39514.1 - 0.73 7.6 2.9 0.99 7.2 2.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-HIT PF04438.16 KIK39514.1 - 2.8 7.9 8.1 5.7 6.9 8.1 1.5 1 0 0 1 1 1 0 HIT zinc finger zf-TFIIB PF13453.6 KIK39514.1 - 6.6 6.1 8.4 1.3e+02 2.0 8.4 2.5 1 1 0 1 1 1 0 Transcription factor zinc-finger zf-H2C2_2 PF13465.6 KIK39516.1 - 5.6e-05 23.4 3.9 0.00016 22.0 3.9 1.8 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK39516.1 - 0.0087 16.8 2.3 0.054 14.4 1.1 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 KIK39516.1 - 0.048 14.1 1.2 3.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIK39516.1 - 0.096 13.0 6.3 1.4 9.3 0.5 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Ribosomal_L35p PF01632.19 KIK39516.1 - 0.11 13.0 0.2 0.11 13.0 0.2 1.8 2 1 0 2 2 2 0 Ribosomal protein L35 zf-C2H2 PF00096.26 KIK39516.1 - 0.23 12.0 7.9 0.11 12.9 1.6 2.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type bZIP_1 PF00170.21 KIK39519.1 - 5.1e-08 32.9 4.1 9.9e-08 32.0 4.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIK39519.1 - 6.6e-06 26.1 7.3 0.0016 18.5 7.3 2.3 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KIK39519.1 - 0.29 11.7 2.8 0.42 11.2 2.8 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor NB-ARC PF00931.22 KIK39521.1 - 6.1e-08 32.2 0.0 7.4e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KIK39521.1 - 2.1e-07 31.3 0.0 3.3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK39521.1 - 4.1e-06 27.3 2.7 3.2e-05 24.4 2.7 2.0 1 1 0 1 1 1 1 AAA ATPase domain Mur_ligase_C PF02875.21 KIK39521.1 - 0.0051 17.0 0.1 0.011 16.0 0.1 1.5 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain NTPase_1 PF03266.15 KIK39521.1 - 0.11 12.4 0.2 13 5.7 0.0 2.2 2 0 0 2 2 2 0 NTPase DAP3 PF10236.9 KIK39521.1 - 0.14 11.3 0.1 0.31 10.1 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 KAP_NTPase PF07693.14 KIK39521.1 - 0.76 9.0 1.8 14 4.8 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain NACHT PF05729.12 KIK39522.1 - 8.1e-08 32.3 0.0 1.7e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KIK39522.1 - 6.7e-05 23.2 0.0 0.0004 20.7 0.0 2.2 1 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KIK39522.1 - 0.0089 15.4 0.1 0.93 8.8 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 KIK39522.1 - 0.011 14.9 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 KIK39522.1 - 0.023 14.1 0.1 0.06 12.7 0.1 1.7 1 1 0 1 1 1 0 KaiC AAA_16 PF13191.6 KIK39522.1 - 0.025 14.9 0.0 0.14 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 KIK39522.1 - 0.13 12.3 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KIK39522.1 - 0.16 12.3 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KIK39522.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF3748 PF12566.8 KIK39524.1 - 0.17 11.9 0.0 0.19 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) CHAT PF12770.7 KIK39525.1 - 1.1e-42 146.5 0.0 1.9e-42 145.7 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK39525.1 - 7.8e-14 51.0 25.0 0.00096 18.9 0.0 8.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIK39525.1 - 5.4e-11 42.6 16.4 0.27 11.6 1.3 8.4 4 1 4 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 KIK39525.1 - 0.00052 19.6 4.1 10 5.9 0.0 5.8 6 0 0 6 6 6 1 TPR repeat TPR_1 PF00515.28 KIK39525.1 - 0.00079 19.1 6.9 10 6.2 0.1 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK39525.1 - 0.0074 16.2 13.6 14 6.0 0.0 7.0 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK39525.1 - 0.012 16.4 18.9 27 6.0 0.7 7.8 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK39525.1 - 0.62 10.3 12.1 26 5.2 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat MFS_1 PF07690.16 KIK39527.1 - 4.4e-12 45.6 44.7 4.4e-12 45.6 44.7 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily Cdc6_C PF09079.11 KIK39529.1 - 0.031 14.2 0.0 0.67 10.0 0.0 2.1 1 1 1 2 2 2 0 CDC6, C terminal winged helix domain GWT1 PF06423.12 KIK39530.1 - 1.9e-40 138.4 0.0 6.7e-40 136.6 0.0 2.0 2 0 0 2 2 2 1 GWT1 SPC12 PF06645.13 KIK39530.1 - 3.6 7.7 7.0 16 5.7 0.3 4.0 4 0 0 4 4 4 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Peptidase_S10 PF00450.22 KIK39531.1 - 3.6e-92 310.0 1.5 4.4e-92 309.7 1.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Acetyltransf_9 PF13527.7 KIK39534.1 - 0.035 14.2 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_5_C PF18564.1 KIK39536.1 - 2.7e-25 88.7 0.0 5.5e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KIK39536.1 - 5.3e-11 42.5 0.0 1.1e-05 25.0 0.0 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) TauD PF02668.16 KIK39537.1 - 5.6e-48 164.1 0.1 7.8e-48 163.6 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KIK39537.1 - 5.3e-12 46.2 0.0 1e-11 45.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF971) Glu_dehyd_C PF16912.5 KIK39537.1 - 0.19 11.2 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus MaoC_dehydratas PF01575.19 KIK39538.1 - 2.4e-27 94.9 0.0 7e-27 93.4 0.0 1.7 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KIK39538.1 - 9.5e-05 22.5 0.0 0.38 10.9 0.0 3.0 2 2 0 2 2 2 2 N-terminal half of MaoC dehydratase BTG PF07742.12 KIK39543.1 - 0.039 13.8 0.0 6.6 6.6 0.0 2.3 1 1 1 2 2 2 0 BTG family Acyl-CoA_dh_1 PF00441.24 KIK39545.1 - 0.0019 18.4 0.2 0.0041 17.3 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Abhydrolase_6 PF12697.7 KIK39546.1 - 1.4e-10 42.2 0.3 1.9e-10 41.7 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KIK39546.1 - 3.2e-05 23.7 0.1 5e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 KIK39546.1 - 0.00026 20.7 0.0 0.00046 19.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK39546.1 - 0.0076 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Lipase_3 PF01764.25 KIK39546.1 - 0.011 15.6 0.1 0.02 14.7 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.8 KIK39546.1 - 0.013 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 KIK39546.1 - 0.083 12.5 0.1 2.2 7.9 0.2 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase DUF4298 PF14131.6 KIK39547.1 - 0.09 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) Meleagrin PF08189.11 KIK39549.1 - 0.08 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Meleagrin/Cygnin family NT-C2 PF10358.9 KIK39552.1 - 1.1e-18 67.4 0.0 2.6e-13 49.9 0.0 2.3 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins UPF0139 PF03669.13 KIK39553.1 - 0.0021 17.9 0.1 0.0026 17.6 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Ribosomal_L28 PF00830.19 KIK39554.1 - 5.8e-16 58.4 0.6 7.6e-16 58.1 0.6 1.1 1 0 0 1 1 1 1 Ribosomal L28 family TRAF6_Z2 PF18048.1 KIK39556.1 - 0.4 10.8 4.1 7.1 6.8 1.0 2.4 1 1 1 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 SET PF00856.28 KIK39557.1 - 8.9e-14 52.2 0.0 2.9e-13 50.6 0.0 1.8 1 1 0 1 1 1 1 SET domain FliN_N PF16973.5 KIK39557.1 - 0.12 12.2 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 Flagellar motor switch protein FliN N-terminal Gemini_mov PF01708.16 KIK39558.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Geminivirus putative movement protein 2OG-FeII_Oxy PF03171.20 KIK39559.1 - 6e-11 42.7 0.0 8.6e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MIF4G PF02854.19 KIK39561.1 - 1.9e-92 308.7 10.1 1.6e-49 168.4 3.6 2.3 2 0 0 2 2 2 2 MIF4G domain eIF_4G1 PF12152.8 KIK39561.1 - 1.2e-16 60.6 0.0 2.9e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 BLM10_mid PF16507.5 KIK39561.1 - 0.051 12.2 0.8 13 4.3 0.1 2.9 3 0 0 3 3 3 0 Proteasome-substrate-size regulator, mid region HSBP1 PF06825.12 KIK39561.1 - 0.057 13.3 0.4 4.8 7.1 0.0 2.6 2 0 0 2 2 2 0 Heat shock factor binding protein 1 TrkH PF02386.16 KIK39562.1 - 1.7e-100 336.9 17.5 1.8e-97 326.9 7.3 2.1 2 0 0 2 2 2 2 Cation transport protein Hum_adeno_E3A PF05393.11 KIK39562.1 - 0.079 12.9 0.2 0.37 10.8 0.2 2.2 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein DUF4345 PF14248.6 KIK39562.1 - 0.12 12.2 0.1 0.12 12.2 0.1 3.9 5 0 0 5 5 5 0 Domain of unknown function (DUF4345) LCM PF04072.14 KIK39565.1 - 3e-25 89.3 0.0 5.8e-25 88.3 0.0 1.5 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase FMN_dh PF01070.18 KIK39566.1 - 2.9e-119 398.2 0.0 3.4e-119 397.9 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KIK39566.1 - 2.4e-20 72.5 0.0 4.9e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KIK39566.1 - 3.4e-05 23.2 0.0 5.1e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KIK39566.1 - 0.0011 18.0 0.2 0.002 17.2 0.2 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain PEP_mutase PF13714.6 KIK39567.1 - 3.1e-44 151.2 1.7 4e-44 150.9 1.7 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KIK39567.1 - 2.5e-19 69.2 0.2 3.4e-19 68.7 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family PEP_hydrolase PF09370.10 KIK39567.1 - 0.0018 17.6 0.1 0.0038 16.5 0.1 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like FMN_dh PF01070.18 KIK39569.1 - 7.5e-122 406.7 0.0 9e-122 406.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KIK39569.1 - 2.4e-19 69.2 0.0 4.9e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 KIK39569.1 - 1.3e-05 24.3 0.1 5.1e-05 22.4 0.1 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KIK39569.1 - 1.7e-05 24.1 0.0 3.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KIK39569.1 - 0.0089 15.4 0.1 0.44 9.8 0.0 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KIK39569.1 - 0.024 13.9 0.0 0.046 12.9 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KIK39569.1 - 0.067 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.15 KIK39569.1 - 0.1 11.9 0.2 0.16 11.4 0.2 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Cu-oxidase PF00394.22 KIK39571.1 - 3.5e-46 157.2 0.1 9.3e-43 146.1 0.0 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK39571.1 - 1.5e-36 125.2 5.0 3.2e-35 120.8 0.2 3.6 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK39571.1 - 2.5e-36 124.3 3.1 1.1e-35 122.2 0.2 2.9 2 1 0 2 2 2 1 Multicopper oxidase Hyd_WA PF06462.12 KIK39572.1 - 0.1 12.6 1.1 1.1 9.3 1.1 2.3 1 1 0 1 1 1 0 Propeller TMEM70 PF06979.12 KIK39573.1 - 8.2e-05 23.0 0.2 0.00012 22.5 0.2 1.3 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex Hexapep PF00132.24 KIK39574.1 - 4.4e-11 42.1 20.9 4.7e-07 29.3 3.7 4.6 4 1 1 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KIK39574.1 - 1.5e-05 24.7 14.3 0.0012 18.5 2.8 3.9 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KIK39574.1 - 0.00054 19.0 0.0 0.00077 18.5 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase Abhydrolase_3 PF07859.13 KIK39575.1 - 4.7e-40 137.7 0.1 2.1e-33 116.0 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK39575.1 - 1.6e-09 37.2 0.0 2.5e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase APH PF01636.23 KIK39577.1 - 1.5e-37 129.8 0.0 2e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIK39577.1 - 5e-07 29.5 0.0 3.4e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 KIK39577.1 - 0.00018 20.9 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 KIK39577.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) HSP70 PF00012.20 KIK39578.1 - 6.2e-263 873.4 11.9 7.2e-263 873.2 11.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIK39578.1 - 1.7e-13 50.1 9.0 7.7e-13 48.0 1.4 3.0 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 KIK39578.1 - 0.23 11.9 9.4 3.5 8.1 0.1 4.0 3 2 0 3 3 3 0 Cell division protein FtsA Corona_S1 PF01600.16 KIK39584.1 - 0.058 12.2 0.0 0.073 11.8 0.0 1.2 1 0 0 1 1 1 0 Coronavirus S1 glycoprotein zf-RVT PF13966.6 KIK39586.1 - 0.00069 20.3 2.3 0.00089 19.9 2.3 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Na_H_Exchanger PF00999.21 KIK39588.1 - 5.7e-45 153.7 52.8 7.8e-45 153.3 52.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CoxIIa PF08113.11 KIK39588.1 - 0.97 9.3 4.8 3.7 7.4 4.8 2.0 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family Na_H_Exchanger PF00999.21 KIK39594.1 - 1.7e-47 162.1 50.8 2.2e-47 161.7 50.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MINDY_DUB PF04424.13 KIK39595.1 - 4.9e-28 97.5 0.0 3.7e-27 94.7 0.0 2.1 2 0 0 2 2 2 1 MINDY deubiquitinase zf-MYND PF01753.18 KIK39596.1 - 1.6e-07 31.3 13.4 3.4e-07 30.2 13.4 1.6 1 0 0 1 1 1 1 MYND finger Cpn10 PF00166.21 KIK39597.1 - 1.2e-28 99.0 0.0 1.3e-28 98.8 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit MFS_1 PF07690.16 KIK39598.1 - 1e-40 139.8 55.2 2.2e-38 132.1 50.6 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK39598.1 - 1.6e-06 27.3 10.1 1.6e-06 27.3 10.1 3.1 3 1 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 KIK39598.1 - 6e-05 21.5 21.7 0.00084 17.8 0.6 4.3 4 1 1 5 5 5 3 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 KIK39598.1 - 0.0033 16.0 35.3 0.031 12.8 3.7 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1 PF07690.16 KIK39599.1 - 9.6e-47 159.6 70.7 2.1e-33 115.7 20.0 3.1 1 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK39599.1 - 1.9e-08 33.7 13.7 1.9e-08 33.7 13.7 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.6 KIK39599.1 - 9e-06 24.5 38.4 0.0012 17.5 22.9 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein OATP PF03137.20 KIK39599.1 - 0.68 8.1 21.7 0.1 10.9 0.6 3.8 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family ICMT PF04140.14 KIK39607.1 - 0.045 14.2 0.9 2.1 8.8 0.1 2.1 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family CreD PF06123.12 KIK39607.1 - 2.2 7.0 6.1 2.7 6.7 6.1 1.0 1 0 0 1 1 1 0 Inner membrane protein CreD SecG PF03840.14 KIK39609.1 - 0.00024 21.1 2.5 0.00031 20.8 0.3 2.5 2 1 1 3 3 3 1 Preprotein translocase SecG subunit MIP PF00230.20 KIK39610.1 - 8.7e-41 140.1 12.3 1e-40 139.9 12.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein TrbC PF04956.13 KIK39610.1 - 0.099 12.9 7.0 0.13 12.5 6.1 1.6 1 1 0 1 1 1 0 TrbC/VIRB2 family PRA1 PF03208.19 KIK39610.1 - 1.2 8.7 6.6 2.1 8.0 6.6 1.4 1 0 0 1 1 1 0 PRA1 family protein RF-1 PF00472.20 KIK39611.1 - 7e-19 67.9 0.2 9.6e-19 67.4 0.2 1.1 1 0 0 1 1 1 1 RF-1 domain DUF829 PF05705.14 KIK39612.1 - 7.3e-38 130.8 0.0 9e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DLH PF01738.18 KIK39612.1 - 0.076 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Myelin_PLP PF01275.19 KIK39612.1 - 0.13 12.1 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) DUF829 PF05705.14 KIK39613.1 - 7.8e-40 137.3 0.4 9.1e-40 137.1 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) F-box-like PF12937.7 KIK39614.1 - 0.0051 16.7 0.4 0.02 14.8 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK39614.1 - 0.098 12.6 0.9 0.24 11.3 0.9 1.7 1 0 0 1 1 1 0 F-box domain DUF4604 PF15377.6 KIK39615.1 - 5.2e-30 105.1 16.6 6.6e-30 104.8 16.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF3807 PF12720.7 KIK39615.1 - 7 6.9 13.6 7.5 6.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Complex1_LYR_2 PF13233.6 KIK39616.1 - 2e-21 76.5 0.1 2.9e-21 76.0 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KIK39616.1 - 5.3e-13 48.8 0.0 8.4e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 KIK39616.1 - 0.0063 17.1 0.1 0.01 16.4 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Cyanate_lyase PF02560.14 KIK39617.1 - 5.1e-34 115.9 0.0 7.3e-34 115.4 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 KIK39617.1 - 0.0016 18.7 0.0 0.0024 18.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KIK39617.1 - 0.052 13.2 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 Linker_histone PF00538.19 KIK39617.1 - 0.073 13.4 0.0 0.16 12.3 0.0 1.5 2 0 0 2 2 2 0 linker histone H1 and H5 family Tubulin PF00091.25 KIK39621.1 - 3.7e-52 177.4 0.0 5.8e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KIK39621.1 - 5.8e-33 113.7 0.0 1e-32 112.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KIK39621.1 - 0.0038 17.5 0.1 0.0085 16.4 0.0 1.7 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KIK39621.1 - 0.038 13.2 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Hus1 PF04005.12 KIK39622.1 - 1.4e-77 260.7 0.1 1.6e-77 260.5 0.1 1.0 1 0 0 1 1 1 1 Hus1-like protein PCNA_C PF02747.15 KIK39622.1 - 0.06 13.5 0.5 0.28 11.3 0.3 2.0 2 0 0 2 2 2 0 Proliferating cell nuclear antigen, C-terminal domain Transketolase_N PF00456.21 KIK39624.1 - 2e-16 59.9 1.8 2.3e-15 56.4 1.8 2.0 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 KIK39624.1 - 6.1e-07 29.4 0.0 1.5e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 KIK39624.1 - 1.7e-05 24.6 0.5 3.4e-05 23.6 0.2 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.21 KIK39624.1 - 2.5e-05 24.1 0.4 9.8e-05 22.2 0.4 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KIK39624.1 - 7.3e-05 21.9 0.1 0.00011 21.2 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component PIG-U PF06728.13 KIK39625.1 - 0.13 11.2 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U Sugar_tr PF00083.24 KIK39626.1 - 2.3e-103 346.5 29.0 2.8e-103 346.2 29.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK39626.1 - 3.4e-23 82.2 50.0 2.9e-22 79.1 42.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cylicin_N PF15241.6 KIK39627.1 - 0.078 13.1 0.3 0.15 12.2 0.3 1.5 1 0 0 1 1 1 0 Cylicin N-terminus Sugar_tr PF00083.24 KIK39628.1 - 8e-103 344.7 31.5 9.1e-103 344.5 31.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK39628.1 - 1.2e-20 73.7 36.9 1.2e-20 73.7 36.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.6 KIK39628.1 - 0.033 14.7 0.1 0.06 13.9 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF805 PF05656.14 KIK39631.1 - 0.77 10.2 4.4 3 8.3 4.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Herpes_UL21 PF03252.13 KIK39633.1 - 0.12 11.1 0.0 0.12 11.1 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL21 TauD PF02668.16 KIK39634.1 - 1e-05 25.5 0.0 1e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Gly_transf_sug PF04488.15 KIK39636.1 - 3.3e-07 30.8 0.0 6.6e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KIK39636.1 - 0.0048 16.3 0.4 0.0078 15.6 0.4 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Arrestin_N PF00339.29 KIK39637.1 - 0.034 14.2 0.0 1.8 8.6 0.0 3.0 4 0 0 4 4 4 0 Arrestin (or S-antigen), N-terminal domain RmlD_sub_bind PF04321.17 KIK39638.1 - 2.4e-56 191.0 0.0 2.9e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KIK39638.1 - 1.1e-25 90.5 0.0 1.5e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK39638.1 - 6.1e-07 29.1 0.0 1e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KIK39638.1 - 4.4e-06 26.1 0.0 4.4e-05 22.8 0.0 2.1 1 1 1 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 KIK39638.1 - 2.7e-05 23.5 0.1 0.0056 15.8 0.1 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KIK39638.1 - 0.00018 20.7 0.0 0.0005 19.2 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 KIK39638.1 - 0.02 15.0 0.1 0.047 13.8 0.1 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Transp_cyt_pur PF02133.15 KIK39640.1 - 3.2e-133 444.7 40.4 3.8e-133 444.5 40.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Thioredoxin_6 PF13848.6 KIK39642.1 - 0.029 14.3 0.0 0.032 14.1 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain Transp_cyt_pur PF02133.15 KIK39643.1 - 1.2e-140 469.2 40.1 1.4e-140 469.0 40.1 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pkinase PF00069.25 KIK39645.1 - 8.1e-45 153.2 0.0 1.2e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK39645.1 - 2.6e-24 85.9 0.0 4.7e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KIK39645.1 - 0.0003 19.9 0.0 0.00055 19.0 0.0 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 KIK39645.1 - 0.005 16.8 0.1 0.0089 16.0 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KIK39645.1 - 0.038 13.6 0.0 3.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KIK39645.1 - 0.081 12.2 0.0 0.15 11.3 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Ribosomal_S5_C PF03719.15 KIK39647.1 - 8.3e-21 73.2 0.1 4.5e-20 70.9 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KIK39647.1 - 1.5e-18 66.5 0.2 4.6e-18 65.0 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain PITH PF06201.13 KIK39648.1 - 2.4e-37 128.5 0.0 2.8e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain ELYS PF13934.6 KIK39649.1 - 5.2e-44 150.9 0.1 7.1e-44 150.4 0.1 1.2 1 0 0 1 1 1 1 Nuclear pore complex assembly MFS_1 PF07690.16 KIK39650.1 - 2.7e-16 59.5 41.6 8e-13 48.0 20.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily B PF02216.16 KIK39650.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 B domain MFS_1 PF07690.16 KIK39651.1 - 1e-10 41.1 35.4 6.6e-05 22.0 28.6 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 KIK39651.1 - 0.0012 17.5 6.6 0.0012 17.5 6.6 2.1 1 1 0 1 1 1 1 MFS/sugar transport protein RETICULATA-like PF11891.8 KIK39651.1 - 0.086 12.7 0.5 0.2 11.5 0.5 1.6 1 0 0 1 1 1 0 Protein RETICULATA-related Sec23_trunk PF04811.15 KIK39652.1 - 9.9e-71 238.1 0.0 3.1e-70 236.5 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KIK39652.1 - 1.7e-25 88.8 0.2 6.4e-25 87.0 0.2 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KIK39652.1 - 1.7e-18 67.1 0.0 4.4e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KIK39652.1 - 3.6e-15 55.7 8.2 6.2e-15 55.0 8.2 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KIK39652.1 - 5.2e-10 39.1 0.0 1.1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.26 KIK39652.1 - 1.2e-06 28.4 0.1 1.2e-06 28.4 0.1 2.0 2 0 0 2 2 2 1 WW domain Vps36-NZF-N PF16988.5 KIK39652.1 - 0.0045 16.4 1.3 0.0098 15.3 1.3 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF3458_C PF17432.2 KIK39652.1 - 0.12 11.7 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3458_C) ARM repeats ATP-synt_10 PF05176.14 KIK39653.1 - 3.3e-62 210.0 0.0 4.1e-62 209.7 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Histone PF00125.24 KIK39654.1 - 1.3e-17 64.4 0.0 1.7e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KIK39654.1 - 3.3e-17 61.9 0.7 6.5e-17 61.0 0.7 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KIK39654.1 - 1.4e-06 28.5 0.0 1.9e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF563 PF04577.14 KIK39655.1 - 4e-09 36.9 0.0 6.3e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) WW PF00397.26 KIK39656.1 - 0.041 14.0 0.1 0.041 14.0 0.1 1.8 2 0 0 2 2 2 0 WW domain CcmD PF04995.14 KIK39657.1 - 0.047 13.8 0.3 0.047 13.8 0.3 2.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Macoilin PF09726.9 KIK39660.1 - 2.9 6.4 3.5 3.2 6.2 3.5 1.0 1 0 0 1 1 1 0 Macoilin family Mannosyl_trans2 PF04188.13 KIK39663.1 - 1.4e-55 189.4 21.6 1.9e-55 189.0 21.6 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) Pex24p PF06398.11 KIK39664.1 - 3e-27 95.6 2.2 3.3e-25 88.9 2.2 2.4 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin WD40 PF00400.32 KIK39665.1 - 1.6e-28 98.3 14.2 8.1e-05 23.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39665.1 - 4.7e-07 30.0 0.2 0.02 15.2 0.0 4.4 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK39665.1 - 0.0003 19.9 0.3 0.18 10.7 0.1 3.5 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5046 PF16465.5 KIK39665.1 - 0.011 15.2 0.2 2.3 7.6 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5046) PQQ PF01011.21 KIK39665.1 - 0.014 15.3 0.2 1.9 8.5 0.0 3.5 4 0 0 4 4 4 0 PQQ enzyme repeat WD40_like PF17005.5 KIK39665.1 - 0.019 14.3 0.0 0.11 11.9 0.0 2.1 2 2 1 3 3 3 0 WD40-like domain Me-amine-dh_H PF06433.11 KIK39665.1 - 0.045 12.6 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) Marek_SORF3 PF07153.11 KIK39665.1 - 0.097 12.0 0.1 0.22 10.9 0.0 1.5 1 1 1 2 2 2 0 Marek's disease-like virus SORF3 protein PQQ_3 PF13570.6 KIK39665.1 - 0.47 11.0 6.3 38 4.9 0.0 4.2 4 1 0 4 4 4 0 PQQ-like domain F-box-like PF12937.7 KIK39666.1 - 7.5e-05 22.5 0.2 0.00017 21.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK39666.1 - 0.078 12.9 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KIK39667.1 - 1.8e-09 37.3 4.3 4.4e-09 36.1 4.3 1.7 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK39667.1 - 0.035 14.0 1.1 20 5.2 0.3 3.0 2 1 1 3 3 3 0 F-box domain MIP-T3_C PF17749.1 KIK39667.1 - 0.13 12.3 0.9 0.15 12.1 0.3 1.4 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Aminotran_1_2 PF00155.21 KIK39668.1 - 2e-41 142.4 0.0 1.5e-20 73.7 0.0 3.4 3 0 0 3 3 3 3 Aminotransferase class I and II LETM1 PF07766.13 KIK39668.1 - 8e-29 100.8 2.4 2.3e-14 53.4 0.4 2.2 1 1 1 2 2 2 2 LETM1-like protein Med27 PF11571.8 KIK39674.1 - 2.1e-09 37.6 0.0 4.7e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit 27 DOCK_N PF16172.5 KIK39676.1 - 1.9e-114 382.6 0.0 2.7e-114 382.0 0.0 1.2 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 KIK39676.1 - 1.4e-73 248.4 1.2 6.6e-73 246.1 1.2 1.9 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 KIK39676.1 - 1.8e-53 181.2 0.0 2.8e-52 177.4 0.0 2.7 3 0 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins DASH_Spc34 PF08657.10 KIK39678.1 - 0.068 13.0 0.6 0.48 10.2 0.3 2.0 1 1 0 1 1 1 0 DASH complex subunit Spc34 Allexi_40kDa PF05549.11 KIK39678.1 - 0.15 11.5 0.1 0.63 9.5 0.2 1.8 2 0 0 2 2 2 0 Allexivirus 40kDa protein GMC_oxred_N PF00732.19 KIK39679.1 - 6.8e-60 202.9 0.0 9.7e-60 202.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK39679.1 - 1.2e-27 97.2 0.0 2.2e-27 96.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK39679.1 - 0.0013 17.8 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK39679.1 - 0.038 13.1 0.8 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain WD40 PF00400.32 KIK39682.1 - 1.2e-05 25.9 0.1 5.1e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat Toxin_35 PF10530.9 KIK39683.1 - 0.0025 17.7 7.7 0.0031 17.4 7.7 1.1 1 0 0 1 1 1 1 Toxin with inhibitor cystine knot ICK or Knottin scaffold Toxin_12 PF07740.12 KIK39683.1 - 0.4 11.4 11.1 0.66 10.7 11.1 1.3 1 0 0 1 1 1 0 Ion channel inhibitory toxin Seryl_tRNA_N PF02403.22 KIK39685.1 - 0.0044 17.2 0.3 0.0066 16.7 0.3 1.2 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Transcrip_act PF04949.13 KIK39685.1 - 0.01 15.7 0.1 0.27 11.1 0.1 2.0 1 1 1 2 2 2 0 Transcriptional activator CALCOCO1 PF07888.11 KIK39685.1 - 0.011 14.7 0.5 0.013 14.3 0.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like VHL_C PF17211.3 KIK39685.1 - 0.019 14.9 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 0 VHL box domain DUF3349 PF11829.8 KIK39685.1 - 0.057 14.2 0.3 0.088 13.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) PilJ PF13675.6 KIK39685.1 - 0.06 13.4 4.5 1 9.4 1.4 2.4 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term RRF PF01765.19 KIK39685.1 - 0.087 12.8 0.7 0.13 12.2 0.7 1.2 1 0 0 1 1 1 0 Ribosome recycling factor Baculo_gp64 PF03273.13 KIK39685.1 - 0.17 10.7 0.2 0.31 9.8 0.2 1.4 1 1 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family CCDC-167 PF15188.6 KIK39685.1 - 0.17 12.3 1.3 0.37 11.2 1.3 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 COG2 PF06148.11 KIK39685.1 - 0.34 11.0 3.9 1.4 9.0 2.1 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 POP1 PF06978.11 KIK39686.1 - 3.9e-45 154.4 13.8 1.1e-24 87.6 4.9 2.5 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KIK39686.1 - 1e-31 109.1 0.5 4e-31 107.2 0.5 2.1 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.21 KIK39686.1 - 0.0099 15.3 0.0 0.16 11.3 0.0 2.4 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain 3Beta_HSD PF01073.19 KIK39687.1 - 3.5e-65 219.8 0.0 1.1e-59 201.8 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KIK39687.1 - 8.7e-31 107.2 0.0 1.3e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK39687.1 - 3.8e-18 66.0 0.1 3.9e-13 49.5 0.1 2.9 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KIK39687.1 - 5.9e-14 51.9 0.0 8.1e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KIK39687.1 - 1.5e-12 47.8 0.0 3.1e-12 46.8 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KIK39687.1 - 4.9e-12 45.6 0.0 4.7e-08 32.5 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KIK39687.1 - 2.9e-05 23.4 0.2 0.00015 21.0 0.2 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KIK39687.1 - 0.01 15.4 0.6 0.3 10.6 0.6 2.2 1 1 0 1 1 1 0 NmrA-like family KR PF08659.10 KIK39687.1 - 0.033 14.1 0.7 0.14 12.1 0.7 2.0 1 1 0 1 1 1 0 KR domain TrkA_N PF02254.18 KIK39687.1 - 0.19 12.0 0.1 0.67 10.2 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain Nbl1_Borealin_N PF10444.9 KIK39688.1 - 2.6e-17 62.2 0.2 6e-17 61.0 0.1 1.8 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal Borealin PF10512.9 KIK39688.1 - 0.00035 20.5 1.1 0.00035 20.5 1.1 3.8 4 0 0 4 4 4 2 Cell division cycle-associated protein 8 Pol_alpha_B_N PF08418.10 KIK39688.1 - 0.05 13.6 1.8 0.13 12.3 0.0 2.3 2 1 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Cu-oxidase PF00394.22 KIK39689.1 - 6.9e-49 166.0 0.1 3.6e-43 147.4 0.0 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK39689.1 - 6.5e-38 129.6 0.1 9.3e-37 125.8 0.2 2.1 2 0 0 2 2 2 1 Multicopper oxidase WD40 PF00400.32 KIK39693.1 - 1.1e-39 133.6 19.8 1.5e-06 28.8 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39693.1 - 1.6e-16 60.4 8.0 4.9e-05 23.5 0.1 5.7 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK39693.1 - 6.1e-07 28.7 0.4 0.4 9.6 0.0 4.9 2 1 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK39693.1 - 1.4e-06 27.3 10.9 0.14 10.8 0.1 4.8 3 2 3 6 6 6 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KIK39693.1 - 0.0026 16.3 0.0 0.48 8.9 0.0 3.0 2 1 2 4 4 4 1 Cytochrome D1 heme domain DUF5570 PF17731.1 KIK39693.1 - 0.0038 17.3 6.3 0.12 12.5 0.3 3.9 3 2 1 4 4 4 1 Family of unknown function (DUF5570) WD40_like PF17005.5 KIK39693.1 - 0.025 13.9 0.0 1.2 8.4 0.0 2.8 1 1 0 2 2 2 0 WD40-like domain Nbas_N PF15492.6 KIK39693.1 - 0.027 13.8 1.6 3.6 6.8 0.0 3.8 1 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 KIK39693.1 - 0.039 12.9 9.0 0.65 8.9 1.0 3.3 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Kelch_6 PF13964.6 KIK39693.1 - 0.055 13.8 0.4 1.8 9.0 0.0 3.5 4 0 0 4 4 4 0 Kelch motif PQQ_3 PF13570.6 KIK39693.1 - 0.057 13.9 8.4 9 6.9 0.7 4.4 3 1 1 4 4 4 0 PQQ-like domain PQQ PF01011.21 KIK39693.1 - 0.14 12.1 2.8 3.1 7.9 0.1 4.0 5 0 0 5 5 5 0 PQQ enzyme repeat WD40 PF00400.32 KIK39694.1 - 4.7e-36 122.2 11.0 1.2e-06 29.2 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39694.1 - 4.1e-16 59.1 5.7 0.0089 16.3 0.0 6.2 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK39694.1 - 5.2e-07 28.7 3.0 0.32 9.6 0.2 4.5 2 1 3 5 5 5 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK39694.1 - 7.3e-06 25.2 0.0 0.58 9.1 0.0 4.5 3 2 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 KIK39694.1 - 0.00013 22.3 2.3 0.096 13.2 0.0 4.3 4 1 0 4 4 4 1 PQQ-like domain WD40_like PF17005.5 KIK39694.1 - 0.00016 21.1 0.0 0.0082 15.5 0.0 3.2 3 1 1 4 4 4 1 WD40-like domain Nbas_N PF15492.6 KIK39694.1 - 0.0065 15.8 0.5 0.27 10.5 0.0 3.3 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PQQ PF01011.21 KIK39694.1 - 0.029 14.3 0.2 1.6e+02 2.5 0.0 4.8 5 0 0 5 5 5 0 PQQ enzyme repeat WD40 PF00400.32 KIK39698.1 - 3.7e-41 138.3 15.0 4.1e-07 30.6 1.7 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39698.1 - 1.4e-14 54.1 4.8 0.0044 17.3 0.2 5.1 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK39698.1 - 3.7e-08 32.5 2.9 0.083 11.5 0.1 4.1 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK39698.1 - 1.3e-05 24.3 0.0 3.2 6.6 0.0 4.8 2 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK39698.1 - 0.00015 21.2 0.0 0.042 13.2 0.0 3.5 3 1 1 4 4 4 2 WD40-like domain PQQ PF01011.21 KIK39698.1 - 0.0014 18.5 0.1 0.26 11.3 0.0 3.8 3 0 0 3 3 3 1 PQQ enzyme repeat Kelch_6 PF13964.6 KIK39698.1 - 0.0091 16.3 1.1 0.91 9.9 0.0 3.8 4 0 0 4 4 4 1 Kelch motif PD40 PF07676.12 KIK39698.1 - 0.019 14.9 0.0 42 4.2 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Hira PF07569.11 KIK39698.1 - 0.027 14.2 0.3 5.9 6.6 0.1 3.6 3 1 1 5 5 5 0 TUP1-like enhancer of split Phage_Mu_Gp45 PF06890.12 KIK39698.1 - 0.11 12.3 0.0 11 5.8 0.0 3.2 1 1 1 3 3 3 0 Bacteriophage Mu Gp45 protein Chordopox_A33R PF05966.12 KIK39700.1 - 0.017 14.4 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Dimer_Tnp_hAT PF05699.14 KIK39707.1 - 3e-13 49.4 0.0 4e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TFCD_C PF12612.8 KIK39708.1 - 0.035 13.9 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal DBD_Tnp_Hermes PF10683.9 KIK39709.1 - 0.017 14.8 0.0 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain zf-RVT PF13966.6 KIK39710.1 - 1.1e-06 29.3 0.5 1.1e-06 29.3 0.5 2.2 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase Tubulin-binding PF00418.19 KIK39711.1 - 0.067 13.2 0.2 0.067 13.2 0.2 2.4 2 0 0 2 2 2 0 Tau and MAP protein, tubulin-binding repeat MICSWaP PF17018.5 KIK39711.1 - 0.13 11.8 0.3 0.22 11.1 0.3 1.3 1 0 0 1 1 1 0 Spore wall protein Cnn_1N PF07989.11 KIK39711.1 - 3.6 7.8 6.5 0.21 11.7 1.3 1.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Cauli_VI PF01693.16 KIK39712.1 - 3.1e-10 40.2 0.1 5e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin KDZ PF18758.1 KIK39713.1 - 1.8e-35 122.6 1.8 1.7e-29 103.0 0.2 2.8 2 1 1 3 3 3 2 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK39713.1 - 1.6e-07 31.4 4.8 1.1e-05 25.6 0.1 3.1 3 0 0 3 3 3 2 CxC2 like cysteine cluster associated with KDZ transposases Pkinase PF00069.25 KIK39715.1 - 1.4e-20 73.7 0.0 6.4e-20 71.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK39715.1 - 4.2e-15 55.7 0.0 1.5e-13 50.6 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 KIK39715.1 - 0.0086 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIK39715.1 - 0.097 12.6 1.2 0.47 10.3 0.1 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Glyoxal_oxid_N PF07250.11 KIK39716.1 - 3.8e-32 111.4 0.0 1e-23 83.8 0.0 3.7 4 0 0 4 4 4 2 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KIK39716.1 - 8e-23 80.6 0.5 1.6e-22 79.6 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 KIK39716.1 - 0.00057 19.8 0.2 0.54 10.3 0.0 3.0 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KIK39716.1 - 0.0064 16.4 0.0 2 8.5 0.0 3.9 3 0 0 3 3 3 1 Kelch motif FYRN PF05964.14 KIK39716.1 - 0.28 11.1 2.0 0.7 9.8 1.6 1.8 2 0 0 2 2 2 0 F/Y-rich N-terminus HSP20 PF00011.21 KIK39718.1 - 0.00011 22.3 0.0 0.0025 17.9 0.0 2.6 2 1 0 2 2 2 1 Hsp20/alpha crystallin family TFIID_20kDa PF03847.13 KIK39719.1 - 4.3e-28 97.6 0.1 7e-28 96.9 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KIK39719.1 - 0.00065 19.9 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KIK39719.1 - 0.0038 17.3 0.2 0.14 12.3 0.0 2.7 3 0 0 3 3 3 1 Centromere kinetochore component CENP-T histone fold TEX13 PF15186.6 KIK39719.1 - 0.023 14.4 0.8 0.036 13.7 0.0 1.6 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family HlyIII PF03006.20 KIK39720.1 - 2.4e-36 125.5 20.2 3.3e-36 125.1 20.2 1.2 1 0 0 1 1 1 1 Haemolysin-III related CREPT PF16566.5 KIK39720.1 - 0.011 15.9 1.8 3.3 7.9 0.7 2.9 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Chloroa_b-bind PF00504.21 KIK39720.1 - 0.17 12.4 0.0 0.33 11.5 0.0 1.5 1 0 0 1 1 1 0 Chlorophyll A-B binding protein Pept_tRNA_hydro PF01195.19 KIK39721.1 - 3.2e-31 108.6 0.0 3.6e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Glyco_hydro_92 PF07971.12 KIK39722.1 - 9.9e-119 397.3 3.0 1.2e-118 397.0 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KIK39722.1 - 6.4e-50 170.3 0.1 1.1e-49 169.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Pkinase PF00069.25 KIK39723.1 - 2e-37 129.0 0.0 2.6e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK39723.1 - 1e-20 74.1 0.0 1.2e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK39723.1 - 6.6e-06 25.2 0.0 2.4e-05 23.3 0.0 1.6 1 1 1 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KIK39723.1 - 0.0002 20.8 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK39723.1 - 0.00061 19.2 0.1 0.00085 18.7 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK39723.1 - 0.0012 18.9 0.0 0.029 14.3 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK39723.1 - 0.034 13.1 0.1 0.038 12.9 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KIK39723.1 - 0.07 12.1 0.0 0.093 11.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3328 PF11807.8 KIK39727.1 - 1.2e-14 54.6 0.6 3e-14 53.4 0.3 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) PHO4 PF01384.20 KIK39728.1 - 0.0079 15.3 5.1 0.0091 15.1 5.1 1.1 1 0 0 1 1 1 1 Phosphate transporter family SlyX PF04102.12 KIK39729.1 - 0.0024 18.4 2.0 0.081 13.6 0.4 2.7 1 1 1 2 2 2 1 SlyX Sec23_helical PF04815.15 KIK39729.1 - 0.0086 15.9 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain ApoLp-III PF07464.11 KIK39729.1 - 0.014 15.5 0.2 0.022 14.8 0.2 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) SURF1 PF02104.15 KIK39734.1 - 1.5e-46 158.9 0.1 2e-46 158.4 0.1 1.2 1 0 0 1 1 1 1 SURF1 family PsbK PF02533.15 KIK39734.1 - 0.052 13.7 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Photosystem II 4 kDa reaction centre component DUF4188 PF13826.6 KIK39734.1 - 0.1 13.0 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4188) ANTH PF07651.16 KIK39735.1 - 1.2e-70 237.7 0.0 1.2e-70 237.7 0.0 2.9 3 0 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 KIK39735.1 - 1.6e-54 184.3 13.0 1.6e-54 184.3 13.0 5.4 4 1 0 5 5 5 1 I/LWEQ domain TcdB_N PF12918.7 KIK39735.1 - 0.0054 17.0 0.4 0.041 14.2 0.0 2.7 2 0 0 2 2 2 1 TcdB toxin N-terminal helical domain ENTH PF01417.20 KIK39735.1 - 0.011 15.8 0.0 0.23 11.5 0.0 3.2 2 0 0 2 2 2 0 ENTH domain FAA_hydro_N_2 PF18288.1 KIK39735.1 - 0.026 14.9 2.3 0.22 12.0 0.5 3.5 2 1 1 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 Ion_trans PF00520.31 KIK39739.1 - 1.6e-05 24.3 2.0 2.1e-05 23.9 2.0 1.1 1 0 0 1 1 1 1 Ion transport protein CWC25 PF12542.8 KIK39740.1 - 1.4e-24 87.0 0.6 1.4e-24 87.0 0.6 4.1 3 2 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 KIK39740.1 - 8.4e-14 51.5 12.5 8.4e-14 51.5 12.5 4.7 3 2 2 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR MFS_1 PF07690.16 KIK39742.1 - 2.3e-47 161.6 39.4 1.8e-44 152.1 23.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK39742.1 - 1.2e-09 37.6 13.1 1.2e-09 37.6 13.1 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KIK39742.1 - 3.3e-09 35.7 6.1 1e-08 34.1 6.6 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KIK39742.1 - 1.1e-06 27.8 0.0 8.1e-05 21.6 0.0 2.7 1 1 0 1 1 1 1 MFS_1 like family DUF5326 PF17260.2 KIK39742.1 - 0.39 10.9 0.1 0.39 10.9 0.1 3.5 5 0 0 5 5 5 0 Family of unknown function (DUF5326) adh_short PF00106.25 KIK39743.1 - 5.7e-35 120.6 0.0 7.2e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK39743.1 - 4.4e-24 85.3 0.0 5.6e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK39743.1 - 7.6e-07 29.2 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KIK39743.1 - 4.2e-05 23.5 0.0 5.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KIK39743.1 - 0.0011 18.1 0.0 0.0015 17.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KIK39743.1 - 0.025 14.1 0.0 0.049 13.1 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KIK39743.1 - 0.054 13.0 0.0 0.086 12.4 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Sacchrp_dh_NADP PF03435.18 KIK39743.1 - 0.099 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DcpS PF05652.12 KIK39744.1 - 1.3e-24 87.0 0.0 2e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 KIK39744.1 - 1e-21 77.6 0.1 1.9e-21 76.6 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding F-box-like PF12937.7 KIK39746.1 - 1.1e-07 31.7 0.2 8e-07 28.9 0.2 2.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK39746.1 - 0.043 13.7 0.0 0.17 11.8 0.0 2.1 1 0 0 1 1 1 0 F-box domain DUF3246 PF11596.8 KIK39746.1 - 0.091 12.2 1.1 0.14 11.6 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Cwf_Cwc_15 PF04889.12 KIK39746.1 - 4.5 6.9 5.1 6.7 6.4 5.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 KIK39746.1 - 9.7 6.6 13.3 19 5.7 13.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ABC1 PF03109.16 KIK39749.1 - 1e-20 74.1 0.0 1.5e-11 44.5 0.0 2.5 2 0 0 2 2 2 2 ABC1 family SAICAR_synt PF01259.18 KIK39750.1 - 1e-99 333.3 0.0 1.3e-99 333.0 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase HHH_5 PF14520.6 KIK39753.1 - 3.2e-05 24.4 0.2 4.8e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.15 KIK39753.1 - 0.0016 18.2 0.2 0.0026 17.5 0.2 1.3 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain DUF1565 PF07602.11 KIK39753.1 - 0.018 14.4 0.0 0.02 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) Glyco_transf_7C PF02709.14 KIK39753.1 - 0.045 13.4 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Hemocyanin_M PF00372.19 KIK39753.1 - 0.052 12.7 0.1 0.068 12.3 0.1 1.1 1 0 0 1 1 1 0 Hemocyanin, copper containing domain HHH_3 PF12836.7 KIK39753.1 - 0.073 13.3 0.1 0.22 11.8 0.1 1.9 1 1 0 1 1 1 0 Helix-hairpin-helix motif LacI PF00356.21 KIK39753.1 - 0.088 12.6 1.0 0.15 11.9 1.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family HNOBA PF07701.14 KIK39753.1 - 0.1 12.0 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Heme NO binding associated Rad51 PF08423.11 KIK39754.1 - 1.3e-14 54.1 0.1 1.4e-14 54.0 0.1 1.0 1 0 0 1 1 1 1 Rad51 Rad51 PF08423.11 KIK39755.1 - 8.4e-17 61.3 0.0 9.6e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 Ribonuclease_T2 PF00445.18 KIK39756.1 - 4.4e-38 131.3 0.1 6.2e-38 130.8 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family SIR2 PF02146.17 KIK39758.1 - 1.4e-34 119.6 0.0 2.4e-21 76.5 0.0 3.0 3 0 0 3 3 3 2 Sir2 family RNA_pol_Rpb6 PF01192.22 KIK39759.1 - 5.4e-15 55.0 0.1 7.8e-15 54.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 RRM_1 PF00076.22 KIK39760.1 - 3.1e-17 62.1 0.0 6.8e-11 41.8 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VHL_C PF17211.3 KIK39760.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 VHL box domain RRM_5 PF13893.6 KIK39760.1 - 0.15 11.7 0.0 0.52 9.9 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GST_N PF02798.20 KIK39761.1 - 1.1e-18 67.3 0.0 1.7e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIK39761.1 - 1.6e-14 54.0 0.0 3.5e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK39761.1 - 8.2e-12 45.2 0.0 1.1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KIK39761.1 - 1.1e-10 41.6 0.0 5e-10 39.5 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIK39761.1 - 2.9e-05 24.2 0.0 5.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK39761.1 - 0.0001 22.2 0.2 0.00021 21.2 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TFIIF_beta PF02270.15 KIK39763.1 - 2.5e-26 91.6 0.1 5.7e-26 90.4 0.1 1.6 2 0 0 2 2 2 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 KIK39763.1 - 3e-17 63.6 0.0 7.9e-17 62.2 0.0 1.8 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 KIK39763.1 - 0.0074 17.1 0.1 0.012 16.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain AAA_18 PF13238.6 KIK39764.1 - 0.00046 20.7 0.0 0.00065 20.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KIK39764.1 - 0.0074 16.7 0.0 0.085 13.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KIK39764.1 - 0.029 14.8 0.0 0.042 14.3 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KIK39764.1 - 0.031 14.4 0.0 0.042 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK39764.1 - 0.036 13.2 0.0 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain SKI PF01202.22 KIK39764.1 - 0.074 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase ABC_tran PF00005.27 KIK39764.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Fun_ATP-synt_8 PF05933.13 KIK39765.1 - 1.6 8.9 9.0 0.57 10.4 0.8 3.3 3 0 0 3 3 3 0 Fungal ATP synthase protein 8 (A6L) Aldo_ket_red PF00248.21 KIK39767.1 - 3.7e-47 160.9 0.0 4.1e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 KIK39768.1 - 1.8e-30 105.9 0.0 2.9e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK39768.1 - 2.6e-05 24.2 5.5 5.2e-05 23.3 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KIK39768.1 - 0.002 18.3 0.0 0.0078 16.3 0.0 2.0 1 0 0 1 1 1 1 Gal4-like dimerisation domain DUF3295 PF11702.8 KIK39769.1 - 4.4e-12 46.1 16.4 4.4e-12 46.1 16.4 2.6 1 1 2 3 3 3 1 Protein of unknown function (DUF3295) Astro_capsid_N PF03115.14 KIK39769.1 - 0.74 8.4 4.9 1.1 7.8 4.9 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor GalKase_gal_bdg PF10509.9 KIK39771.1 - 2.5e-21 74.9 0.3 5.1e-21 74.0 0.3 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KIK39771.1 - 1.7e-14 53.7 1.7 3.4e-14 52.8 0.7 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KIK39771.1 - 2.2e-11 43.9 0.0 5.9e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Aldose_epim PF01263.20 KIK39773.1 - 6.4e-24 84.8 0.2 1.5e-22 80.3 0.2 2.6 1 1 0 1 1 1 1 Aldose 1-epimerase S10_plectin PF03501.15 KIK39775.1 - 1.3e-45 153.4 0.5 1.5e-45 153.2 0.5 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 KIK39775.1 - 0.021 14.7 0.1 0.035 14.0 0.1 1.5 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Replic_Relax PF13814.6 KIK39775.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Replication-relaxation PPI_Ypi1 PF07491.11 KIK39777.1 - 5.2e-27 93.5 3.7 8.6e-27 92.8 3.7 1.4 1 0 0 1 1 1 1 Protein phosphatase inhibitor zf-MYND PF01753.18 KIK39778.1 - 1.6e-11 44.1 9.5 3.5e-11 43.0 9.5 1.6 1 0 0 1 1 1 1 MYND finger zf_C2H2_13 PF18508.1 KIK39778.1 - 0.058 13.0 2.9 0.74 9.5 0.5 2.6 1 1 1 2 2 2 0 Zinc finger domain zf-C6H2 PF15801.5 KIK39778.1 - 0.086 13.2 6.9 0.17 12.2 6.9 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding IDO PF01231.18 KIK39780.1 - 2.5e-135 451.7 0.0 2.9e-135 451.4 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Pneumo_NS1 PF03438.13 KIK39780.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Pneumovirus NS1 protein AAA PF00004.29 KIK39781.1 - 2.7e-16 60.2 0.0 5.4e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.18 KIK39781.1 - 2.5e-13 50.0 0.0 6.4e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 BAH domain AAA_16 PF13191.6 KIK39781.1 - 3.7e-11 43.7 0.0 2.2e-10 41.2 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIK39781.1 - 5.3e-07 30.0 0.0 1.1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 KIK39781.1 - 1.7e-06 28.1 0.1 4.2e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 AAA lid domain DUF2075 PF09848.9 KIK39781.1 - 3.5e-05 23.2 0.0 0.00014 21.2 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KIK39781.1 - 0.00082 19.7 0.0 0.002 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIK39781.1 - 0.0027 17.7 0.0 0.024 14.5 0.0 2.5 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea NACHT PF05729.12 KIK39781.1 - 0.03 14.2 0.0 0.12 12.3 0.0 2.1 2 1 0 2 2 2 0 NACHT domain AAA_11 PF13086.6 KIK39781.1 - 0.037 13.8 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KIK39781.1 - 0.081 12.1 0.0 0.18 11.0 0.0 1.5 2 0 0 2 2 2 0 TIP49 P-loop domain NTPase_1 PF03266.15 KIK39781.1 - 0.084 12.8 0.5 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 KIK39781.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-MYND PF01753.18 KIK39782.1 - 8.8e-07 28.9 10.6 2e-06 27.7 10.6 1.7 1 0 0 1 1 1 1 MYND finger eIF-6 PF01912.18 KIK39783.1 - 4.9e-81 270.8 0.9 5e-81 270.8 0.2 1.3 2 0 0 2 2 2 1 eIF-6 family Methyltransf_28 PF02636.17 KIK39784.1 - 1.4e-60 205.2 0.0 1.7e-60 204.9 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Bin3 PF06859.12 KIK39786.1 - 5.9e-36 123.4 0.0 8.1e-36 122.9 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 KIK39786.1 - 4.3e-10 39.6 0.0 4.5e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KIK39786.1 - 6.6e-10 39.1 0.0 1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK39786.1 - 9.7e-09 35.8 0.0 8.4e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KIK39786.1 - 8e-07 29.6 0.1 0.00091 19.8 0.0 2.5 3 0 0 3 3 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KIK39786.1 - 3.3e-05 24.5 0.0 0.45 11.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_4 PF02390.17 KIK39786.1 - 0.00097 18.6 0.0 0.011 15.2 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.7 KIK39786.1 - 0.016 15.2 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KIK39786.1 - 0.045 13.3 0.0 0.1 12.2 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain Spermine_synth PF01564.17 KIK39786.1 - 0.057 12.8 0.0 4.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Spermine/spermidine synthase domain Methyltransf_9 PF08003.11 KIK39786.1 - 0.1 11.5 0.0 0.21 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PrmA PF06325.13 KIK39786.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KIK39786.1 - 0.2 11.6 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF5137 PF17220.3 KIK39787.1 - 0.016 16.1 0.2 0.024 15.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF5137) UCH PF00443.29 KIK39790.1 - 3e-42 144.9 0.0 6.2e-42 143.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIK39790.1 - 2.4e-09 37.2 0.5 0.0007 19.3 0.0 3.4 3 1 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase Aminotran_1_2 PF00155.21 KIK39791.1 - 8.5e-58 196.3 0.0 9.7e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.32 KIK39792.1 - 1.7e-23 82.5 13.1 9.1e-10 39.0 3.1 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39792.1 - 1.2e-06 28.7 1.5 0.0024 18.1 0.3 3.6 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK39792.1 - 0.00035 19.6 0.0 0.52 9.2 0.0 3.1 2 2 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cellulase PF00150.18 KIK39793.1 - 1.1e-43 149.7 0.2 1.5e-43 149.2 0.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 KIK39795.1 - 3.2e-47 161.3 0.1 3.9e-47 161.0 0.1 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) WD40 PF00400.32 KIK39797.1 - 1.6e-18 66.7 15.7 0.0014 19.4 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39797.1 - 1.1e-08 35.2 4.3 0.019 15.3 0.4 4.8 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK39797.1 - 6.6e-06 25.3 0.2 0.11 11.5 0.1 4.0 3 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein 2-Hacid_dh_C PF02826.19 KIK39798.1 - 5.6e-39 133.3 0.0 8.7e-39 132.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIK39798.1 - 1e-27 96.4 0.0 1.2e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KIK39798.1 - 0.005 17.4 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KIK39798.1 - 0.011 15.9 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase CTP_synth_N PF06418.14 KIK39802.1 - 4.9e-122 406.3 0.2 6.3e-122 406.0 0.2 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KIK39802.1 - 6e-52 176.2 0.0 1e-51 175.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KIK39802.1 - 0.0032 17.2 0.1 0.15 11.8 0.0 2.3 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 KIK39802.1 - 0.044 13.8 0.0 0.088 12.9 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DEAD PF00270.29 KIK39803.1 - 2.9e-39 134.6 0.0 7.5e-39 133.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK39803.1 - 3e-20 72.6 0.1 6.9e-18 65.0 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KIK39803.1 - 3.4e-05 23.9 0.0 0.00013 22.0 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 KIK39804.1 - 2.7e-07 30.8 9.1 5e-07 29.9 9.1 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KIK39804.1 - 1.4e-05 25.2 5.2 3.3e-05 24.0 5.2 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 KIK39804.1 - 0.0026 18.0 7.6 0.0056 16.9 7.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KIK39804.1 - 0.0036 17.3 2.2 0.0077 16.3 2.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KIK39804.1 - 0.046 13.3 6.0 0.091 12.4 6.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KIK39804.1 - 0.072 13.2 7.3 0.17 12.1 7.3 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.6 KIK39804.1 - 0.12 12.2 8.8 0.25 11.2 8.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KIK39804.1 - 0.14 12.5 7.6 0.28 11.5 7.6 1.6 1 0 0 1 1 1 0 RING-like domain zf-C3HC4 PF00097.25 KIK39804.1 - 0.24 11.3 9.9 0.45 10.4 9.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 KIK39804.1 - 2.3 8.2 6.6 4.9 7.1 6.6 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_4 PF14570.6 KIK39804.1 - 2.3 8.1 6.0 4.3 7.2 6.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain NCOA_u2 PF16665.5 KIK39808.1 - 0.089 13.1 0.8 0.098 13.0 0.5 1.3 1 1 0 1 1 1 0 Unstructured region on nuclear receptor coactivator protein WD40 PF00400.32 KIK39809.1 - 1.6e-06 28.7 3.6 0.00056 20.7 0.1 2.5 2 1 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39809.1 - 0.00051 20.3 0.2 0.00069 19.9 0.2 1.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain SAP PF02037.27 KIK39810.1 - 0.0002 21.1 0.1 0.00033 20.3 0.1 1.3 1 0 0 1 1 1 1 SAP domain DUF2189 PF09955.9 KIK39810.1 - 0.098 12.9 6.7 2.6 8.3 1.7 2.2 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) Nterm_IS4 PF13006.7 KIK39810.1 - 0.14 12.4 0.7 0.54 10.5 0.1 2.2 3 0 0 3 3 3 0 Insertion element 4 transposase N-terminal DUF2101 PF09874.9 KIK39810.1 - 0.15 11.7 0.1 0.23 11.1 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) DUF908 PF06012.12 KIK39810.1 - 0.54 9.6 3.0 0.78 9.1 3.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) TFA2_Winged_2 PF18121.1 KIK39812.1 - 9.1e-20 70.1 0.1 1.9e-19 69.1 0.1 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KIK39812.1 - 4.4e-16 58.9 0.4 1.1e-14 54.4 0.2 2.4 2 0 0 2 2 2 1 TFIIE beta subunit core domain WD40 PF00400.32 KIK39813.1 - 1.9e-05 25.3 3.8 0.00012 22.8 0.3 3.0 3 1 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39813.1 - 0.0005 20.3 0.0 0.02 15.2 0.0 2.4 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Bromo_TP PF07524.13 KIK39814.1 - 0.0015 18.5 0.0 0.0031 17.5 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 KIK39814.1 - 0.0056 17.0 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Transp_cyt_pur PF02133.15 KIK39815.1 - 1.2e-105 353.9 37.9 1.4e-105 353.7 37.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pkinase PF00069.25 KIK39816.1 - 1.8e-43 148.9 0.0 2.7e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK39816.1 - 7.9e-43 146.6 0.0 1.1e-42 146.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK39816.1 - 0.015 15.2 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK39816.1 - 0.017 14.0 0.0 0.033 13.0 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 KIK39816.1 - 0.019 14.3 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIK39816.1 - 0.037 13.0 0.0 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain p450 PF00067.22 KIK39817.1 - 8.1e-65 219.3 0.0 9.3e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rap_GAP PF02145.15 KIK39818.1 - 8.5e-45 152.6 0.0 1.4e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KIK39818.1 - 2e-41 142.3 0.0 1.9e-39 135.8 0.0 2.2 2 0 0 2 2 2 2 Tuberin DUF3384 PF11864.8 KIK39818.1 - 6.6e-07 28.6 0.0 8.1e-06 25.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) SF1-HH PF16275.5 KIK39819.1 - 1.9e-39 134.5 0.8 5e-39 133.1 0.8 1.8 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 KIK39819.1 - 9.7e-12 44.4 8.3 1.4e-05 24.9 0.3 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 KIK39819.1 - 1.2e-06 28.4 3.9 0.004 17.1 1.6 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.29 KIK39819.1 - 7.3e-06 25.7 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.6 KIK39819.1 - 0.0029 17.3 6.7 0.25 11.1 0.5 2.4 2 0 0 2 2 2 2 Zinc knuckle CCDC-167 PF15188.6 KIK39819.1 - 0.0049 17.2 1.6 3.2 8.2 0.1 2.4 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 167 zf-CCHC_6 PF15288.6 KIK39819.1 - 0.035 13.9 10.0 0.4 10.6 0.8 2.9 3 0 0 3 3 3 0 Zinc knuckle Prim_Zn_Ribbon PF08273.12 KIK39819.1 - 0.21 11.9 3.2 0.46 10.8 3.2 1.5 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase DnaJ_CXXCXGXG PF00684.19 KIK39819.1 - 0.27 11.6 4.3 0.65 10.4 4.3 1.6 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_2 PF13696.6 KIK39819.1 - 3.3 7.6 9.3 0.35 10.7 0.7 2.5 2 0 0 2 2 2 0 Zinc knuckle GEN1_C PF18380.1 KIK39820.1 - 1e-29 103.5 0.0 1e-29 103.5 0.0 3.4 4 1 0 4 4 4 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 KIK39820.1 - 1.5e-17 63.7 0.0 3.8e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KIK39820.1 - 6.4e-05 23.4 0.0 0.00021 21.7 0.0 1.9 1 1 0 1 1 1 1 XPG N-terminal domain WD40 PF00400.32 KIK39821.1 - 0.0015 19.3 0.1 1.6 9.8 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Fn3-like PF14310.6 KIK39821.1 - 0.15 12.2 0.2 0.5 10.5 0.1 1.8 2 0 0 2 2 2 0 Fibronectin type III-like domain WD40 PF00400.32 KIK39822.1 - 0.023 15.5 0.0 0.036 14.9 0.0 1.3 1 0 0 1 1 1 0 WD domain, G-beta repeat LIM PF00412.22 KIK39824.1 - 1.4e-25 89.3 20.1 5.1e-13 49.0 6.4 2.2 2 0 0 2 2 2 2 LIM domain Zn-ribbon_8 PF09723.10 KIK39824.1 - 0.00094 19.3 17.0 1.3 9.2 2.4 4.3 4 0 0 4 4 4 3 Zinc ribbon domain zf_UBZ PF18439.1 KIK39824.1 - 0.0034 16.9 14.7 1.5 8.5 0.1 4.7 5 0 0 5 5 5 3 Ubiquitin-Binding Zinc Finger zf-ACC PF17848.1 KIK39824.1 - 0.017 15.2 5.1 6.8 6.9 0.2 3.8 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain zinc_ribbon_12 PF11331.8 KIK39824.1 - 0.84 9.5 12.1 0.86 9.5 1.0 3.3 3 0 0 3 3 3 0 Probable zinc-ribbon domain YacG PF03884.14 KIK39824.1 - 0.89 9.3 7.1 5.1 6.9 0.1 3.5 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG DUF4428 PF14471.6 KIK39824.1 - 7.2 6.6 10.6 0.38 10.7 0.4 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4428) zinc_ribbon_13 PF09855.9 KIK39824.1 - 8.7 6.6 7.1 5.1 7.3 0.2 3.2 3 1 0 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) eIF-5a PF01287.20 KIK39825.1 - 7.1e-25 86.9 0.3 1e-24 86.4 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KIK39825.1 - 0.051 13.6 0.1 0.076 13.1 0.1 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain STATa_Ig PF18214.1 KIK39826.1 - 0.12 12.4 0.2 0.19 11.7 0.1 1.4 1 1 0 1 1 1 0 STATa Immunoglobulin-like domain RRM_1 PF00076.22 KIK39827.1 - 3.2e-32 110.2 0.2 9.2e-15 54.2 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK39827.1 - 5.7e-09 36.0 0.0 3.3e-05 23.9 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif OB_RNB PF08206.11 KIK39827.1 - 0.0053 16.4 0.3 0.44 10.3 0.0 2.4 2 0 0 2 2 2 1 Ribonuclease B OB domain Nup35_RRM_2 PF14605.6 KIK39827.1 - 0.0071 16.3 0.0 0.29 11.2 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KIK39827.1 - 0.18 11.8 0.0 6.4 6.9 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif Sporozoite_P67 PF05642.11 KIK39827.1 - 7.6 4.5 15.1 0.051 11.7 5.7 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen COG7 PF10191.9 KIK39828.1 - 4e-65 220.5 0.0 2.3e-37 128.7 0.0 3.4 3 1 0 3 3 3 3 Golgi complex component 7 (COG7) SLATT_1 PF18181.1 KIK39828.1 - 0.82 9.6 3.5 16 5.5 0.0 3.3 3 1 1 4 4 4 0 SMODS and SLOG-associating 2TM effector domain 1 VHS PF00790.19 KIK39829.1 - 1.9e-15 57.0 0.0 3.6e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KIK39829.1 - 1.7e-06 28.2 0.0 0.0031 17.8 0.0 3.0 2 0 0 2 2 2 2 GAT domain PET117 PF15786.5 KIK39829.1 - 9 6.6 9.2 30 5.0 9.2 1.9 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial TAFII28 PF04719.14 KIK39830.1 - 4.6e-34 116.4 0.1 6.6e-34 115.9 0.1 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 KIK39830.1 - 0.0067 16.7 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PRMT5 PF05185.16 KIK39830.1 - 0.038 13.8 0.0 0.052 13.4 0.0 1.1 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Pkinase PF00069.25 KIK39834.1 - 4e-64 216.5 0.0 4e-63 213.2 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK39834.1 - 1.1e-37 129.8 0.0 1e-23 84.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIK39834.1 - 7.4e-06 25.5 0.0 1.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIK39834.1 - 0.014 15.3 14.6 0.035 14.0 0.1 3.7 2 2 1 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK39834.1 - 0.075 12.0 0.0 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain PgdA_N PF18627.1 KIK39834.1 - 0.13 11.9 1.9 0.11 12.1 0.4 1.6 2 0 0 2 2 2 0 Peptidoglycan GlcNAc deacetylase N-terminal domain CoA_transf_3 PF02515.17 KIK39834.1 - 0.13 11.3 2.9 0.21 10.7 2.9 1.3 1 0 0 1 1 1 0 CoA-transferase family III Duffy_binding PF05424.11 KIK39834.1 - 0.19 11.8 1.5 0.34 10.9 1.5 1.3 1 0 0 1 1 1 0 Duffy binding domain DUF4407 PF14362.6 KIK39834.1 - 5.5 6.2 14.2 3.2 7.0 5.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Abhydrolase_6 PF12697.7 KIK39837.1 - 2.3e-06 28.4 0.5 2.3e-06 28.4 0.5 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK39837.1 - 8.6e-05 22.3 0.3 0.00019 21.2 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 KIK39837.1 - 0.073 12.6 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF3939 PF13075.6 KIK39837.1 - 0.088 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) zf-C2H2 PF00096.26 KIK39838.1 - 0.012 16.0 0.0 0.012 16.0 0.0 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK39838.1 - 0.078 13.8 0.0 0.078 13.8 0.0 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger Arm PF00514.23 KIK39839.1 - 1.1e-19 69.8 21.5 6.2e-06 26.1 0.0 9.1 10 0 0 10 10 9 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KIK39839.1 - 5.7e-11 42.7 4.4 0.072 13.5 0.0 6.8 5 2 1 6 6 6 3 HEAT repeats HEAT PF02985.22 KIK39839.1 - 4e-09 35.9 13.7 0.0044 17.2 0.1 7.4 7 0 0 7 7 7 2 HEAT repeat Adaptin_N PF01602.20 KIK39839.1 - 7.5e-08 31.4 8.9 3.7e-07 29.1 1.9 3.6 2 2 0 2 2 2 1 Adaptin N terminal region HEAT_EZ PF13513.6 KIK39839.1 - 1.1e-05 25.7 14.3 0.82 10.2 0.1 6.3 6 2 1 7 7 6 3 HEAT-like repeat DUF3361 PF11841.8 KIK39839.1 - 3.5e-05 23.8 0.3 0.45 10.5 0.0 3.7 2 1 1 3 3 3 2 Domain of unknown function (DUF3361) Cnd1 PF12717.7 KIK39839.1 - 3.6e-05 23.8 6.3 0.00089 19.3 0.3 3.8 3 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 RICTOR_N PF14664.6 KIK39839.1 - 5.9e-05 22.2 1.7 0.0005 19.2 0.2 2.6 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term V-ATPase_H_C PF11698.8 KIK39839.1 - 0.00037 20.6 0.9 0.3 11.2 0.0 4.5 3 1 2 5 5 5 2 V-ATPase subunit H IFRD PF05004.13 KIK39839.1 - 0.00075 18.7 2.6 0.022 13.9 0.0 3.2 3 0 0 3 3 3 1 Interferon-related developmental regulator (IFRD) Atx10homo_assoc PF09759.9 KIK39839.1 - 0.0033 17.4 1.8 12 6.0 0.0 4.3 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_N PF03224.14 KIK39839.1 - 0.0035 16.7 4.2 0.24 10.7 0.8 3.1 2 1 1 3 3 3 2 V-ATPase subunit H RasGEF_N_2 PF14663.6 KIK39839.1 - 0.0042 17.5 0.2 6.4 7.2 0.0 3.0 2 0 0 2 2 2 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm_2 PF04826.13 KIK39839.1 - 0.056 12.9 0.7 6.8 6.1 0.0 3.2 2 1 2 4 4 4 0 Armadillo-like Nipped-B_C PF12830.7 KIK39839.1 - 0.13 12.2 0.1 1 9.3 0.0 2.6 2 1 0 2 2 2 0 Sister chromatid cohesion C-terminus Uso1_p115_head PF04869.14 KIK39839.1 - 0.36 9.9 3.3 5.4 6.1 0.1 3.3 1 1 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, head region DUF3808 PF10300.9 KIK39840.1 - 5.9e-76 256.1 0.0 8.8e-76 255.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 KIK39840.1 - 0.0003 21.0 2.5 0.67 10.3 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK39840.1 - 0.00055 19.9 1.2 0.82 10.0 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK39840.1 - 0.00076 19.9 6.0 7.4 7.2 0.0 5.3 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK39840.1 - 0.0016 19.0 5.2 1.2 9.8 0.4 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK39840.1 - 0.0021 18.0 3.9 1.2 9.4 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK39840.1 - 0.0031 18.2 4.2 0.54 11.2 0.1 4.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIK39840.1 - 0.0085 16.7 0.8 66 4.5 0.0 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK39840.1 - 0.021 15.1 2.9 0.041 14.1 0.1 2.8 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Orthopox_A5L PF06193.11 KIK39840.1 - 0.078 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like TPR_1 PF00515.28 KIK39840.1 - 0.46 10.4 2.3 13 5.8 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat CoaE PF01121.20 KIK39841.1 - 1.6e-58 197.3 0.0 1.9e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KIK39841.1 - 4e-05 24.2 0.1 0.00022 21.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KIK39841.1 - 0.018 15.3 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KIK39841.1 - 0.067 13.6 0.1 7.4 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Pirin PF02678.16 KIK39843.1 - 1.6e-29 102.1 0.2 3e-29 101.1 0.2 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KIK39843.1 - 5.1e-26 91.0 0.0 2.2e-25 89.0 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KIK39843.1 - 0.04 13.6 1.1 0.7 9.7 1.0 2.4 2 0 0 2 2 2 0 Cupin domain AA_permease PF00324.21 KIK39848.1 - 8.2e-114 380.8 38.0 1e-113 380.5 38.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK39848.1 - 3e-30 105.4 40.4 4e-30 105.0 40.4 1.2 1 0 0 1 1 1 1 Amino acid permease ECH_1 PF00378.20 KIK39849.1 - 3e-25 89.0 0.1 4.4e-25 88.4 0.1 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIK39849.1 - 6.3e-16 58.8 0.0 8.5e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase TraP PF07296.11 KIK39849.1 - 0.1 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 TraP protein DUF382 PF04037.13 KIK39850.1 - 2e-57 192.8 0.1 6.5e-57 191.2 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 KIK39850.1 - 1.8e-17 62.9 4.6 3.9e-17 61.8 4.6 1.6 1 0 0 1 1 1 1 PSP Arrestin_C PF02752.22 KIK39851.1 - 2.3e-08 34.6 0.0 5.9e-07 30.0 0.0 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KIK39851.1 - 0.069 13.2 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain HSF_DNA-bind PF00447.17 KIK39852.1 - 3.5e-32 110.9 0.3 5.8e-32 110.2 0.3 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding KxDL PF10241.9 KIK39852.1 - 0.039 14.2 0.8 15 5.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein Ets PF00178.22 KIK39852.1 - 0.2 12.1 0.1 0.4 11.2 0.1 1.5 1 0 0 1 1 1 0 Ets-domain TFIIA PF03153.13 KIK39852.1 - 0.34 10.9 9.8 0.015 15.3 4.4 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit LPP PF04728.13 KIK39852.1 - 2 8.9 4.2 3.1 8.3 1.1 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF3825 PF12873.7 KIK39853.1 - 0.039 13.4 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) ARL6IP6 PF15062.6 KIK39853.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix Glyco_hydro_30 PF02055.16 KIK39853.1 - 0.11 11.4 0.0 8.3 5.3 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 TIM-barrel domain WD40 PF00400.32 KIK39854.1 - 2.8e-10 40.6 11.6 2.5e-07 31.3 1.2 2.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Gmad1 PF10647.9 KIK39854.1 - 0.00013 21.9 0.1 0.16 11.7 0.0 2.0 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 KIK39854.1 - 0.0042 15.8 0.0 0.15 10.7 0.0 2.0 2 0 0 2 2 2 2 Nucleoporin Nup120/160 DUF1513 PF07433.11 KIK39854.1 - 0.0096 15.0 0.3 0.015 14.4 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1513) CHAP PF05257.16 KIK39854.1 - 3.8 8.2 7.8 4.8 7.8 0.7 2.2 1 1 1 2 2 2 0 CHAP domain TPR_10 PF13374.6 KIK39855.1 - 0.0028 17.5 35.0 3.8 7.5 1.1 9.9 10 4 0 10 10 10 4 Tetratricopeptide repeat AKAP7_NLS PF10469.9 KIK39855.1 - 0.0066 16.4 0.0 23 4.8 0.0 4.7 4 2 1 6 6 6 1 AKAP7 2'5' RNA ligase-like domain Suv3_C_1 PF18147.1 KIK39855.1 - 0.17 11.8 1.3 92 3.0 0.0 4.0 4 0 0 4 4 4 0 Suv3 C-terminal domain 1 GMC_oxred_N PF00732.19 KIK39858.1 - 1.1e-51 176.0 0.0 1.4e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK39858.1 - 9e-30 104.1 0.0 1.6e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK39858.1 - 0.02 15.1 0.1 0.067 13.4 0.0 2.0 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain p450 PF00067.22 KIK39859.1 - 1.4e-55 188.9 0.0 1.8e-55 188.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Saf_2TM PF18303.1 KIK39860.1 - 0.11 12.1 3.8 1.3 8.6 0.5 2.5 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain GMP_synt_C PF00958.22 KIK39862.1 - 1.7e-44 149.8 0.1 3.1e-44 148.9 0.1 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 KIK39862.1 - 1.5e-32 113.0 0.0 2.4e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 KIK39862.1 - 1.2e-09 37.6 0.3 6.7e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KIK39862.1 - 4.5e-06 26.6 0.0 1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 KIK39862.1 - 0.003 16.4 0.1 0.0051 15.6 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 KIK39862.1 - 0.0065 16.1 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 KIK39862.1 - 0.01 15.4 0.0 0.028 13.9 0.0 1.8 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 KIK39862.1 - 0.062 12.6 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase MetJ PF01340.20 KIK39862.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Met Apo-repressor, MetJ ATP_bind_3 PF01171.20 KIK39862.1 - 0.094 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 PP-loop family PAPS_reduct PF01507.19 KIK39862.1 - 0.18 11.9 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family UbiA PF01040.18 KIK39864.1 - 1.7e-27 96.4 9.6 2.4e-27 95.9 9.6 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family MFS_1 PF07690.16 KIK39865.1 - 8.2e-42 143.4 36.3 8.2e-42 143.4 36.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK39865.1 - 1e-14 54.3 5.9 1e-14 54.3 5.9 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KIK39865.1 - 2.2e-06 27.2 2.7 2.2e-06 27.2 2.7 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB GMC_oxred_N PF00732.19 KIK39866.1 - 8.6e-66 222.3 0.0 1.5e-65 221.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK39866.1 - 5.6e-35 121.0 0.0 9.8e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK39866.1 - 4.9e-05 23.5 0.1 0.00015 21.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK39866.1 - 0.0013 17.8 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK39866.1 - 0.0014 17.7 0.6 0.016 14.3 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KIK39866.1 - 0.0022 17.6 0.1 0.015 14.9 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIK39866.1 - 0.0055 16.0 0.0 0.0095 15.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KIK39866.1 - 0.12 11.5 0.0 0.41 9.8 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK39866.1 - 0.19 10.9 0.0 1.6 7.9 0.0 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Hanta_nucleocap PF00846.18 KIK39867.1 - 0.17 10.3 0.2 0.29 9.5 0.2 1.3 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein F-box-like PF12937.7 KIK39871.1 - 0.0052 16.6 0.1 0.013 15.3 0.0 1.7 2 0 0 2 2 2 1 F-box-like XRN_N PF03159.18 KIK39874.1 - 1.2e-97 326.1 0.0 1.4e-97 325.9 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus NES_C_h PF18208.1 KIK39875.1 - 0.0036 17.5 0.0 0.0052 17.0 0.0 1.3 1 0 0 1 1 1 1 Nicking enzyme C-terminal middle helical domain Exonuc_VIII PF06630.11 KIK39875.1 - 0.01 15.7 0.1 0.013 15.4 0.1 1.1 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII DUF3976 PF13121.6 KIK39875.1 - 0.2 11.8 0.2 0.33 11.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3976) XRN1_D1 PF18332.1 KIK39876.1 - 5.5e-77 257.9 0.0 1.1e-76 257.0 0.0 1.5 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN_M PF17846.1 KIK39876.1 - 2e-30 106.1 4.7 2.1e-29 102.8 2.5 2.5 2 1 0 2 2 2 1 Xrn1 helical domain XRN1_D2_D3 PF18334.1 KIK39876.1 - 3.1e-30 104.2 0.6 6.8e-30 103.1 0.1 1.9 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KIK39876.1 - 1.4e-23 82.8 0.2 2.9e-23 81.7 0.2 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KIK39876.1 - 2.8e-08 33.8 1.3 5.2e-08 32.9 1.3 1.5 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 BCA_ABC_TP_C PF12399.8 KIK39876.1 - 0.17 11.9 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter Mito_carr PF00153.27 KIK39877.1 - 3.7e-54 180.6 4.3 1.2e-18 66.8 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KIK39877.1 - 0.00057 19.1 0.0 0.05 12.7 0.0 2.4 2 0 0 2 2 2 2 Gammaproteobacterial serine protease TBPIP PF07106.13 KIK39878.1 - 1.1e-13 50.9 0.0 2e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain Penicillinase_R PF03965.16 KIK39878.1 - 0.036 14.4 0.0 0.07 13.5 0.0 1.5 1 0 0 1 1 1 0 Penicillinase repressor TMCO5 PF14992.6 KIK39878.1 - 0.062 12.9 0.2 0.076 12.6 0.2 1.2 1 0 0 1 1 1 0 TMCO5 family DUF1128 PF06569.11 KIK39878.1 - 0.12 12.4 0.1 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) TrmB PF01978.19 KIK39878.1 - 0.15 12.0 0.0 0.58 10.1 0.0 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Seryl_tRNA_N PF02403.22 KIK39878.1 - 0.42 10.9 3.2 0.37 11.0 0.8 2.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4449 PF14613.6 KIK39879.1 - 1.6e-13 51.1 0.4 4e-12 46.5 0.0 3.3 4 1 0 4 4 4 1 Protein of unknown function (DUF4449) Baculo_PEP_C PF04513.12 KIK39879.1 - 0.049 13.7 0.4 0.62 10.1 0.0 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CdvA PF18822.1 KIK39879.1 - 0.13 12.1 2.2 0.17 11.7 0.1 2.2 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Activator-TraM PF11657.8 KIK39879.1 - 2.8 7.8 7.6 0.15 11.9 1.4 2.0 2 0 0 2 2 2 0 Transcriptional activator TraM LprI PF07007.12 KIK39879.1 - 3.2 8.5 6.1 1.2 9.9 0.8 2.5 2 0 0 2 2 2 0 Lysozyme inhibitor LprI DUF262 PF03235.14 KIK39879.1 - 6.5 6.9 5.8 3.5 7.7 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF262 TMEM192 PF14802.6 KIK39881.1 - 0.016 14.3 0.2 0.016 14.3 0.2 2.4 2 1 0 2 2 2 0 TMEM192 family TPR_10 PF13374.6 KIK39882.1 - 1.1e-12 47.3 5.9 0.15 12.0 0.7 7.9 7 1 0 7 7 7 3 Tetratricopeptide repeat CHAT PF12770.7 KIK39882.1 - 2.5e-09 37.0 0.0 5.5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 KIK39882.1 - 7.4e-09 35.8 13.7 0.41 11.0 0.2 8.5 4 2 4 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 KIK39882.1 - 7.7e-06 25.5 5.5 4.9 7.2 0.0 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK39882.1 - 4.9e-05 23.1 0.3 9.6 6.5 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat MIT PF04212.18 KIK39882.1 - 5.3e-05 23.2 0.2 0.37 10.9 0.0 4.3 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 KIK39882.1 - 0.00049 20.7 8.9 39 5.4 0.1 8.3 9 1 1 10 10 10 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK39882.1 - 0.0014 18.6 0.1 47 4.5 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK39882.1 - 0.0057 16.7 9.5 11 6.4 0.1 7.6 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIK39882.1 - 0.18 12.3 0.6 10 6.7 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat 3HCDH_N PF02737.18 KIK39884.1 - 9e-34 116.9 2.9 1.4e-32 113.0 2.9 2.4 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KIK39884.1 - 7.5e-05 23.3 0.0 0.00021 21.8 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Fanconi_A PF03511.14 KIK39884.1 - 0.14 12.1 0.0 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 Fanconi anaemia group A protein DUF1843 PF08898.10 KIK39886.1 - 0.18 12.3 0.3 0.29 11.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) PI-PLC-X PF00388.19 KIK39887.1 - 7.3e-56 187.8 0.1 1.8e-55 186.5 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KIK39887.1 - 1.6e-43 147.7 0.1 3.3e-43 146.7 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KIK39887.1 - 2.4e-07 31.0 0.0 8.3e-06 26.0 0.0 2.9 2 1 0 2 2 2 1 C2 domain EF-hand_7 PF13499.6 KIK39887.1 - 7.7e-05 23.1 1.6 0.00045 20.6 0.7 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_10 PF14788.6 KIK39887.1 - 0.0018 18.1 1.3 0.0018 18.1 1.3 2.4 2 0 0 2 2 2 1 EF hand EF-hand_like PF09279.11 KIK39887.1 - 0.028 14.9 0.1 10 6.7 0.0 2.9 2 1 1 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.32 KIK39887.1 - 0.13 11.9 0.1 1.4 8.7 0.1 2.7 2 0 0 2 2 2 0 EF hand SUI1 PF01253.22 KIK39889.1 - 2.7e-23 82.3 0.4 5.4e-23 81.3 0.4 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Glyco_hydro_35 PF01301.19 KIK39890.1 - 3.5e-78 263.4 0.1 5.1e-78 262.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KIK39890.1 - 4.4e-57 191.6 3.5 2.1e-32 112.0 0.1 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KIK39890.1 - 5.4e-35 120.8 0.4 1.2e-34 119.7 0.4 1.6 1 1 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KIK39890.1 - 3.6e-20 71.3 0.2 8.3e-20 70.1 0.2 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Amidohydro_2 PF04909.14 KIK39890.1 - 0.01 15.7 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase Glyco_hydro_42 PF02449.15 KIK39890.1 - 0.029 13.7 0.2 0.23 10.8 0.2 2.0 1 1 0 1 1 1 0 Beta-galactosidase ABC_tran PF00005.27 KIK39892.1 - 4.5e-47 160.0 0.0 3e-24 86.1 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KIK39892.1 - 4.8e-21 74.6 3.7 4.8e-21 74.6 3.7 2.3 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.6 KIK39892.1 - 6.1e-14 52.5 6.0 0.013 15.4 0.3 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIK39892.1 - 1.3e-09 37.7 0.5 0.00013 21.6 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KIK39892.1 - 1.6e-09 38.6 2.7 0.0015 19.0 0.0 3.8 4 0 0 4 4 3 2 AAA domain SMC_N PF02463.19 KIK39892.1 - 6.8e-09 35.5 2.3 0.38 10.1 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIK39892.1 - 2e-07 31.6 0.0 0.0071 16.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIK39892.1 - 4.6e-06 26.6 1.7 0.0047 16.8 0.0 3.4 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 KIK39892.1 - 5.6e-06 26.4 0.1 0.007 16.4 0.1 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase NACHT PF05729.12 KIK39892.1 - 2.2e-05 24.4 0.0 0.081 12.8 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.6 KIK39892.1 - 7.1e-05 22.7 9.4 0.044 13.5 0.1 4.0 3 2 1 4 4 3 2 AAA ATPase domain AAA_28 PF13521.6 KIK39892.1 - 0.00091 19.5 0.0 0.21 11.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.17 KIK39892.1 - 0.00092 19.4 5.3 0.87 9.6 0.1 4.3 5 1 0 5 5 5 2 Helicase HerA, central domain Dynamin_N PF00350.23 KIK39892.1 - 0.0011 19.0 8.8 0.22 11.6 0.2 4.3 2 2 1 3 3 3 2 Dynamin family AAA_24 PF13479.6 KIK39892.1 - 0.0012 18.6 0.1 1.9 8.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KIK39892.1 - 0.0014 19.1 0.1 3.7 8.1 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KIK39892.1 - 0.0022 17.7 0.0 0.36 10.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KIK39892.1 - 0.0025 17.2 0.1 0.81 9.0 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family G-alpha PF00503.20 KIK39892.1 - 0.0038 16.5 0.3 1.7 7.8 0.0 2.9 3 1 0 3 3 3 1 G-protein alpha subunit AAA_22 PF13401.6 KIK39892.1 - 0.0054 17.0 0.0 4.9 7.4 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 KIK39892.1 - 0.0087 16.5 0.2 25 5.3 0.0 4.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 KIK39892.1 - 0.0089 15.6 0.0 1.3 8.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KIK39892.1 - 0.014 15.8 2.5 6.1 7.3 0.0 3.4 3 0 0 3 3 3 0 RNA helicase AAA_33 PF13671.6 KIK39892.1 - 0.015 15.5 0.0 12 6.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 KIK39892.1 - 0.021 14.0 0.0 5.6 6.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain MukB PF04310.12 KIK39892.1 - 0.021 14.6 0.3 0.63 9.8 0.0 3.1 4 0 0 4 4 3 0 MukB N-terminal AAA_14 PF13173.6 KIK39892.1 - 0.024 14.7 0.0 21 5.2 0.0 3.8 4 0 0 4 4 3 0 AAA domain Roc PF08477.13 KIK39892.1 - 0.031 14.5 0.0 14 5.9 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KIK39892.1 - 0.034 13.9 0.9 6 6.6 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 KIK39892.1 - 0.045 13.7 2.5 3.6 7.5 0.1 3.3 4 0 0 4 4 3 0 NTPase AAA_17 PF13207.6 KIK39892.1 - 0.045 14.2 0.8 7.6 7.0 0.0 3.6 4 0 0 4 4 3 0 AAA domain AAA_5 PF07728.14 KIK39892.1 - 0.071 13.1 0.2 11 6.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 KIK39892.1 - 0.079 12.6 0.6 2 8.0 0.0 2.8 4 0 0 4 4 3 0 ATP synthase alpha/beta family, nucleotide-binding domain MeaB PF03308.16 KIK39892.1 - 0.091 11.7 0.0 11 4.8 0.0 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Thymidylate_kin PF02223.17 KIK39892.1 - 0.094 12.4 2.9 23 4.6 0.0 3.9 4 0 0 4 4 4 0 Thymidylate kinase cobW PF02492.19 KIK39892.1 - 0.12 11.9 0.1 16 5.1 0.2 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.6 KIK39892.1 - 0.26 9.9 6.4 0.93 8.1 0.0 3.4 3 1 1 4 4 4 0 AAA domain DivIC PF04977.15 KIK39892.1 - 4.9 7.0 7.3 14 5.6 1.7 2.7 2 0 0 2 2 2 0 Septum formation initiator FAD_binding_4 PF01565.23 KIK39894.1 - 9.5e-17 61.0 1.6 2.1e-16 59.9 1.6 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIK39894.1 - 4.7e-09 36.2 1.4 8.5e-09 35.4 1.4 1.4 1 0 0 1 1 1 1 Berberine and berberine like zinc_ribbon_10 PF10058.9 KIK39895.1 - 6.6e-20 70.6 0.3 1e-19 70.0 0.3 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein zf-ACC PF17848.1 KIK39895.1 - 0.029 14.4 1.0 0.058 13.5 1.0 1.5 1 1 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain Zn_Tnp_IS1595 PF12760.7 KIK39895.1 - 0.16 12.0 0.7 0.31 11.1 0.3 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.10 KIK39895.1 - 1.3 8.8 4.6 4.4 7.1 4.6 1.8 1 1 0 1 1 1 0 A2L zinc ribbon domain Hydrophobin PF01185.18 KIK39898.1 - 8e-08 32.8 5.8 1e-07 32.5 5.8 1.1 1 0 0 1 1 1 1 Fungal hydrophobin CLIP_SPH_mas PF18398.1 KIK39898.1 - 0.73 10.3 8.0 3.3 8.2 1.2 2.2 2 0 0 2 2 2 0 Clip-domain serine protease homolog masquerade WD40 PF00400.32 KIK39900.1 - 6.2e-133 428.8 58.7 1.3e-09 38.5 0.6 15.8 15 1 1 16 16 16 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK39900.1 - 1.7e-49 166.0 0.0 0.014 15.7 0.0 14.3 2 2 12 14 14 14 13 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK39900.1 - 1.7e-36 125.8 10.3 0.038 12.9 0.0 14.1 6 3 6 14 14 14 11 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK39900.1 - 6.5e-25 86.5 25.9 0.25 11.3 0.0 14.4 15 0 0 15 15 15 8 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK39900.1 - 3.7e-14 52.8 0.0 1.4 8.2 0.0 9.0 9 1 1 10 10 10 3 WD40-like domain AAA_16 PF13191.6 KIK39900.1 - 9.3e-09 35.9 0.1 2.9e-08 34.3 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain eIF2A PF08662.11 KIK39900.1 - 3.9e-08 33.4 0.0 1.6 8.6 0.0 5.8 1 1 5 6 6 6 2 Eukaryotic translation initiation factor eIF2A NACHT PF05729.12 KIK39900.1 - 2.1e-06 27.8 0.0 4.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Frtz PF11768.8 KIK39900.1 - 8.1e-05 21.1 0.0 1.3 7.3 0.0 5.8 3 2 6 10 10 10 1 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 KIK39900.1 - 8.8e-05 21.3 14.4 2.5 6.6 0.0 9.7 6 4 7 13 13 13 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KIK39900.1 - 0.0001 22.0 18.9 0.035 13.7 0.5 3.9 1 1 2 3 3 3 3 PQQ-like domain Nbas_N PF15492.6 KIK39900.1 - 0.00088 18.7 12.3 9.7 5.4 0.0 8.8 10 2 2 12 12 12 0 Neuroblastoma-amplified sequence, N terminal AAA PF00004.29 KIK39900.1 - 0.0017 18.8 0.0 0.006 17.0 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cuticle_4 PF15955.5 KIK39900.1 - 0.0067 17.1 3.4 2.4e+02 2.5 0.0 7.3 9 0 0 9 9 7 0 Cuticle protein AAA_22 PF13401.6 KIK39900.1 - 0.0087 16.3 0.0 0.051 13.9 0.0 2.3 3 0 0 3 3 3 1 AAA domain WD40_3 PF15911.5 KIK39900.1 - 0.038 14.0 6.3 57 3.8 0.0 8.1 10 0 0 10 10 10 0 WD domain, G-beta repeat Parvo_NS1 PF01057.17 KIK39900.1 - 0.056 12.5 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 KIK39900.1 - 0.11 12.9 0.0 0.6 10.5 0.0 2.4 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.20 KIK39900.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase PQQ PF01011.21 KIK39900.1 - 0.26 11.3 3.0 28 4.9 0.0 5.8 9 0 0 9 9 7 0 PQQ enzyme repeat F-box-like PF12937.7 KIK39903.1 - 4e-06 26.6 2.1 9.1e-06 25.5 2.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK39903.1 - 1.2e-05 25.1 1.5 2.5e-05 24.0 1.5 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KIK39903.1 - 0.3 11.0 1.5 1 9.3 0.3 2.2 2 0 0 2 2 2 0 F-box HEAT PF02985.22 KIK39904.1 - 3.4e-06 26.8 4.0 0.97 9.9 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat Pkinase PF00069.25 KIK39904.1 - 4.8e-05 22.9 0.0 7.8e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Cnd1 PF12717.7 KIK39904.1 - 0.00025 21.1 0.3 0.0011 19.0 0.0 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIK39904.1 - 0.00029 21.1 0.2 1.5 9.3 0.0 3.4 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 KIK39904.1 - 0.0004 20.8 1.6 1.2 9.7 0.0 4.2 4 0 0 4 4 4 1 HEAT-like repeat Pkinase_Tyr PF07714.17 KIK39904.1 - 0.0034 16.7 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Adaptin_N PF01602.20 KIK39904.1 - 0.19 10.3 0.0 8.9 4.7 0.0 2.0 1 1 1 2 2 2 0 Adaptin N terminal region DASH_Dad2 PF08654.10 KIK39906.1 - 0.0015 18.9 0.0 0.0023 18.3 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad2 MannoseP_isomer PF01050.18 KIK39910.1 - 0.048 13.6 0.6 0.049 13.5 0.6 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase KDZ PF18758.1 KIK39911.1 - 9.5e-17 61.4 0.1 1.8e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DEC-1_N PF04625.13 KIK39915.1 - 7 5.5 25.4 0.062 12.3 9.5 3.4 2 1 1 3 3 3 0 DEC-1 protein, N-terminal region Plavaka PF18759.1 KIK39918.1 - 5.8e-28 98.1 1.3 8e-26 91.0 0.0 2.4 1 1 1 2 2 2 2 Plavaka transposase RVT_thumb PF06817.14 KIK39921.1 - 0.0067 16.2 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase thumb domain Telomere_reg-2 PF10193.9 KIK39923.1 - 1.2e-30 106.2 0.0 2.7e-30 105.0 0.0 1.7 1 0 0 1 1 1 1 Telomere length regulation protein Aldo_ket_red PF00248.21 KIK39924.1 - 9.2e-52 176.1 0.0 1e-51 175.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF5494 PF17598.2 KIK39924.1 - 0.15 12.2 0.0 0.5 10.5 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5494) 2Fe-2S_thioredx PF01257.19 KIK39925.1 - 4.8e-57 191.9 0.0 5.8e-57 191.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DctP PF03480.13 KIK39925.1 - 0.15 11.3 0.0 0.99 8.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 Bestrophin PF01062.21 KIK39926.1 - 6.8e-38 130.7 0.0 8.7e-37 127.1 0.0 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel FixQ PF05545.11 KIK39926.1 - 0.0098 15.8 1.4 4.8 7.2 0.5 3.0 2 0 0 2 2 2 2 Cbb3-type cytochrome oxidase component FixQ RAB3GAP2_N PF14655.6 KIK39929.1 - 0.11 11.7 0.0 0.32 10.2 0.0 1.6 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Rab5-bind PF09311.11 KIK39931.1 - 0.005 16.3 1.0 0.006 16.0 1.0 1.1 1 0 0 1 1 1 1 Rabaptin-like protein DUF1722 PF08349.11 KIK39931.1 - 0.0076 16.5 0.2 0.012 15.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) DUF2347 PF09804.9 KIK39931.1 - 0.02 14.5 0.4 0.022 14.3 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) SIMPL PF04402.14 KIK39931.1 - 0.091 13.2 0.4 0.13 12.7 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF541) zinc_ribbon_12 PF11331.8 KIK39934.1 - 0.00097 18.9 0.1 0.077 12.8 0.0 2.5 2 0 0 2 2 2 1 Probable zinc-ribbon domain zinc_ribbon_4 PF13717.6 KIK39934.1 - 0.0038 17.1 1.1 1.6 8.7 0.1 2.5 2 0 0 2 2 2 2 zinc-ribbon domain Eapp_C PF10238.9 KIK39934.1 - 0.058 13.5 6.7 0.35 10.9 2.2 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein HypA PF01155.19 KIK39934.1 - 0.074 13.1 0.9 0.76 9.8 0.1 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 KIK39934.1 - 0.1 12.2 2.3 0.87 9.2 0.2 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger YABBY PF04690.13 KIK39934.1 - 0.2 12.2 2.9 0.63 10.6 3.0 1.8 1 1 0 1 1 1 0 YABBY protein DUF3795 PF12675.7 KIK39934.1 - 1.3 9.5 5.7 11 6.5 5.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) Pox_MCEL PF03291.16 KIK39935.1 - 6.2e-88 295.1 0.0 9.6e-88 294.5 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme ERAP1_C PF11838.8 KIK39935.1 - 1.4e-64 218.7 0.3 2.4e-64 217.9 0.3 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KIK39935.1 - 7.5e-64 215.3 0.1 4.2e-63 212.8 0.1 2.2 1 1 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KIK39935.1 - 7e-47 160.0 1.5 3.1e-44 151.4 1.5 2.5 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain Methyltransf_25 PF13649.6 KIK39935.1 - 3.6e-13 50.0 0.0 1.9e-12 47.7 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK39935.1 - 3.7e-09 36.6 0.0 8.9e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK39935.1 - 1.4e-08 34.7 0.0 3.3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK39935.1 - 4.5e-07 30.5 0.0 1.1e-06 29.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK39935.1 - 3.3e-06 27.6 0.0 1.1e-05 25.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KIK39935.1 - 0.00077 18.7 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family MTS PF05175.14 KIK39935.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain HECT PF00632.25 KIK39936.1 - 7.7e-93 311.3 0.0 1e-92 311.0 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KIK39936.1 - 3.7e-36 122.9 19.4 2.7e-13 49.8 5.1 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.30 KIK39936.1 - 1.2e-20 73.8 0.2 3.8e-20 72.1 0.2 1.9 1 0 0 1 1 1 1 C2 domain DUF3275 PF11679.8 KIK39940.1 - 0.0057 16.7 0.3 0.0057 16.7 0.3 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3275) bZIP_1 PF00170.21 KIK39940.1 - 0.0062 16.6 7.6 1.1 9.4 0.5 3.6 3 0 0 3 3 3 2 bZIP transcription factor CCDC-167 PF15188.6 KIK39940.1 - 0.05 13.9 1.1 0.05 13.9 1.1 3.1 3 1 1 4 4 4 0 Coiled-coil domain-containing protein 167 APC_N_CC PF16689.5 KIK39940.1 - 0.078 13.1 0.7 0.17 12.0 0.7 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain Herpes_IE68 PF02479.16 KIK39940.1 - 0.083 12.5 0.2 0.19 11.3 0.2 1.5 1 0 0 1 1 1 0 Herpesvirus immediate early protein Matrilin_ccoil PF10393.9 KIK39940.1 - 0.11 12.4 0.3 0.37 10.7 0.3 1.9 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Cnn_1N PF07989.11 KIK39940.1 - 0.12 12.6 9.7 0.53 10.5 0.4 3.4 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 JIP_LZII PF16471.5 KIK39940.1 - 0.24 11.6 13.9 0.11 12.6 1.6 3.3 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II DUF5320 PF17253.2 KIK39940.1 - 0.4 11.8 0.2 0.4 11.8 0.2 2.4 3 0 0 3 3 2 0 Family of unknown function (DUF5320) DUF2383 PF09537.10 KIK39940.1 - 0.58 10.5 10.6 0.14 12.5 0.6 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) TSC22 PF01166.18 KIK39940.1 - 1 9.7 5.5 7.2 7.0 0.4 3.5 3 1 0 3 3 3 0 TSC-22/dip/bun family DUF4407 PF14362.6 KIK39940.1 - 1.1 8.6 11.4 0.056 12.8 4.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ZapB PF06005.12 KIK39940.1 - 2.1 8.9 18.0 10 6.6 2.4 3.7 3 0 0 3 3 3 0 Cell division protein ZapB DUF16 PF01519.16 KIK39940.1 - 3.2 8.3 7.0 18 5.9 0.9 3.2 2 1 0 2 2 2 0 Protein of unknown function DUF16 TMF_TATA_bd PF12325.8 KIK39940.1 - 9.2 6.5 16.4 1 9.6 1.1 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Mog1 PF04603.12 KIK39941.1 - 2.4e-23 83.0 0.1 2.9e-23 82.8 0.1 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Ndc80_HEC PF03801.13 KIK39942.1 - 1.2e-33 115.9 0.0 2.5e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 KIK39942.1 - 2.2e-07 30.8 0.7 2.2e-07 30.8 0.7 4.0 3 2 1 5 5 5 1 Domain of unknown function (DUF5595) DUF1664 PF07889.12 KIK39942.1 - 0.27 11.3 20.4 0.39 10.8 4.6 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF2935 PF11155.8 KIK39942.1 - 0.32 11.3 5.9 0.87 9.9 1.0 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF2935) DUF724 PF05266.14 KIK39942.1 - 0.53 10.1 19.4 0.034 14.0 3.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Phage_GP20 PF06810.11 KIK39942.1 - 1.8 8.4 21.8 0.067 13.0 3.4 3.2 3 0 0 3 3 3 0 Phage minor structural protein GP20 XhlA PF10779.9 KIK39942.1 - 3.8 7.8 8.8 4.5 7.5 0.6 3.1 2 0 0 2 2 2 0 Haemolysin XhlA DUF2371 PF10177.9 KIK39943.1 - 0.27 11.4 0.5 2.4 8.3 0.5 2.3 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) RNase_T PF00929.24 KIK39944.1 - 3.2e-11 44.1 0.0 4.8e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RepB-RCR_reg PF10723.9 KIK39944.1 - 0.11 12.5 0.0 0.69 9.9 0.0 2.2 2 0 0 2 2 2 0 Replication regulatory protein RepB CMS1 PF14617.6 KIK39945.1 - 3.5e-80 269.0 2.3 4.1e-80 268.7 2.3 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KIK39945.1 - 0.032 14.0 0.0 0.052 13.3 0.0 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase L31 PF09784.9 KIK39946.1 - 2.6e-41 140.2 0.1 2.9e-41 140.0 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 PRP21_like_P PF12230.8 KIK39947.1 - 4.7e-46 157.4 13.6 4.7e-46 157.4 13.6 3.0 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KIK39947.1 - 2.3e-34 117.2 0.6 7.3e-18 64.3 0.1 2.7 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 KIK39947.1 - 3.3e-07 29.9 0.0 9.3e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family zf_UBZ PF18439.1 KIK39947.1 - 0.0013 18.3 0.1 0.0032 17.0 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Rad60-SLD PF11976.8 KIK39947.1 - 0.099 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Med19 PF10278.9 KIK39947.1 - 0.12 12.3 10.8 0.12 12.3 0.3 3.1 3 0 0 3 3 3 0 Mediator of RNA pol II transcription subunit 19 DUF2407 PF10302.9 KIK39947.1 - 0.44 11.1 3.0 1.4 9.5 0.1 3.2 4 0 0 4 4 4 0 DUF2407 ubiquitin-like domain eIF3_N PF09440.10 KIK39947.1 - 1.9 8.9 5.2 0.23 11.9 0.3 2.0 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain UQ_con PF00179.26 KIK39949.1 - 2.6e-18 66.0 0.0 3.8e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF4658 PF15555.6 KIK39949.1 - 0.01 15.9 0.2 0.017 15.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) RWD PF05773.22 KIK39949.1 - 0.13 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 RWD domain CHCH PF06747.13 KIK39950.1 - 1.8e-05 24.8 1.9 2.2e-05 24.5 1.9 1.1 1 0 0 1 1 1 1 CHCH domain Plavaka PF18759.1 KIK39954.1 - 3.1e-108 361.8 0.0 4.4e-108 361.4 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase MtrG PF04210.13 KIK39957.1 - 0.16 11.9 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G DDE_3 PF13358.6 KIK39959.1 - 4.5e-10 39.5 0.0 5e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 KIK39960.1 - 0.0031 17.1 0.2 0.004 16.8 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_38 PF13936.6 KIK39960.1 - 0.0048 16.6 0.5 0.022 14.5 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.6 KIK39960.1 - 0.0076 16.9 0.0 0.0098 16.5 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KIK39960.1 - 0.013 15.7 0.0 0.015 15.5 0.0 1.1 1 0 0 1 1 1 0 Transposase CPSase_L_D3 PF02787.19 KIK39960.1 - 0.027 14.8 0.0 0.029 14.7 0.0 1.1 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DUF647 PF04884.14 KIK39962.1 - 3e-77 259.5 2.3 4.7e-77 258.9 2.3 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Sin3a_C PF16879.5 KIK39963.1 - 2.7e-76 257.0 0.0 7.8e-75 252.2 0.0 2.9 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 KIK39963.1 - 7.7e-37 125.3 0.1 2.3e-36 123.8 0.1 1.8 2 0 0 2 2 2 1 Sin3 family co-repressor PAH PF02671.21 KIK39963.1 - 7.8e-34 115.6 2.4 3.1e-16 59.2 0.0 4.0 3 1 1 4 4 4 3 Paired amphipathic helix repeat MFS_1 PF07690.16 KIK39965.1 - 8.3e-12 44.7 35.4 8.3e-12 44.7 35.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily GST_N_3 PF13417.6 KIK39966.1 - 2.4e-12 47.1 0.0 4e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK39966.1 - 7.5e-11 42.2 0.1 1.4e-10 41.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK39966.1 - 8.3e-08 32.4 0.0 1.3e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK39966.1 - 1.6e-05 24.8 0.0 6e-05 23.0 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIK39966.1 - 0.00059 20.0 0.0 0.0018 18.5 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK39966.1 - 0.0011 19.1 0.0 0.017 15.3 0.0 2.4 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain zf-CSL PF05207.13 KIK39967.1 - 1e-21 76.4 0.7 1.2e-21 76.1 0.7 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 KIK39967.1 - 0.0015 18.6 0.8 0.0022 18.1 0.8 1.3 1 0 0 1 1 1 1 Zinc ribbon domain CobS PF02654.15 KIK39969.1 - 0.14 12.4 4.1 0.038 14.2 1.0 1.7 1 1 0 1 1 1 0 Cobalamin-5-phosphate synthase F-box PF00646.33 KIK39970.1 - 0.037 13.9 0.8 0.12 12.3 0.8 1.8 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KIK39970.1 - 0.055 13.4 0.9 0.12 12.2 0.9 1.6 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.16 KIK39971.1 - 7.4e-20 71.2 59.2 5.4e-13 48.6 23.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KIK39972.1 - 4.9e-16 58.6 59.4 2.3e-11 43.2 32.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KIK39973.1 - 1.2e-16 60.6 58.0 5.9e-10 38.6 41.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KIK39977.1 - 8e-20 71.0 53.3 3.7e-13 49.1 22.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CUE PF02845.16 KIK39982.1 - 3e-09 36.4 0.1 5.5e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 CUE domain SET PF00856.28 KIK39983.1 - 1.3e-18 67.9 0.0 2.7e-18 66.9 0.0 1.5 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KIK39983.1 - 2.2e-08 34.9 0.0 4.1e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SDA1 PF05285.12 KIK39983.1 - 3.3 7.0 7.7 4.9 6.5 7.7 1.2 1 0 0 1 1 1 0 SDA1 FAD_binding_3 PF01494.19 KIK39984.1 - 1.5e-21 77.0 0.1 3e-21 76.1 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KIK39984.1 - 1e-08 34.9 0.4 0.0021 17.4 0.3 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KIK39984.1 - 9e-07 28.4 0.8 0.00023 20.5 0.4 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK39984.1 - 2.2e-06 27.5 9.3 0.00035 20.3 6.1 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIK39984.1 - 2.3e-06 26.8 3.3 0.0062 15.4 0.0 2.2 1 1 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.12 KIK39984.1 - 2.6e-06 26.8 1.7 0.019 14.1 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 KIK39984.1 - 5.9e-06 26.4 1.1 5.9e-06 26.4 1.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIK39984.1 - 2.7e-05 24.6 0.2 0.00079 19.9 0.5 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK39984.1 - 0.00018 20.8 0.5 0.0003 20.1 0.5 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KIK39984.1 - 0.0017 17.1 3.6 0.094 11.4 2.3 2.7 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 KIK39984.1 - 0.0018 17.4 6.0 0.0019 17.3 4.6 1.7 1 1 1 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KIK39984.1 - 0.01 15.3 3.6 0.018 14.4 3.6 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KIK39984.1 - 0.023 13.8 3.3 0.042 12.9 2.7 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KIK39984.1 - 0.067 13.1 1.7 0.13 12.1 1.7 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KIK39984.1 - 0.069 12.4 0.4 0.45 9.7 0.6 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 KIK39984.1 - 0.075 12.9 0.3 0.14 12.0 0.3 1.4 1 0 0 1 1 1 0 Rossmann-like domain ApbA PF02558.16 KIK39984.1 - 0.25 11.0 1.9 0.47 10.1 1.9 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 KIK39984.1 - 0.84 9.2 2.4 1.3 8.5 2.4 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CRAL_TRIO PF00650.20 KIK39985.1 - 5.1e-16 58.8 0.0 8.2e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain DUF4279 PF14106.6 KIK39985.1 - 0.2 11.9 0.3 1.8 8.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) Metallophos PF00149.28 KIK39986.1 - 8e-36 124.5 0.3 1e-35 124.1 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KIK39986.1 - 0.05 14.1 0.6 0.11 13.0 0.6 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 KIK39986.1 - 0.16 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain zf-C2H2 PF00096.26 KIK39988.1 - 3.1e-10 39.9 10.4 2.3e-05 24.6 0.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK39988.1 - 4.3e-08 33.3 8.5 0.001 19.7 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK39988.1 - 3.5e-06 27.1 1.1 0.051 13.9 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KIK39988.1 - 6e-05 22.8 4.3 0.018 15.0 0.2 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KIK39988.1 - 0.00051 19.7 5.2 0.0048 16.6 0.4 2.4 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-met PF12874.7 KIK39988.1 - 0.0018 18.6 0.8 0.065 13.6 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KIK39988.1 - 0.0026 17.7 3.5 0.13 12.3 0.3 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-BED PF02892.15 KIK39988.1 - 0.0029 17.6 2.4 0.0089 16.0 0.5 2.3 2 0 0 2 2 2 1 BED zinc finger PyrI_C PF02748.15 KIK39988.1 - 0.018 14.9 0.4 0.31 11.0 0.1 2.2 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-H2C2_2 PF13465.6 KIK39988.1 - 0.072 13.6 11.2 1.5 9.4 1.1 3.5 3 1 0 3 3 3 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 KIK39988.1 - 0.14 12.5 2.1 1.5 9.2 0.2 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF629 PF04780.12 KIK39988.1 - 1.1 7.7 2.9 9.1 4.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) FYVE PF01363.21 KIK39988.1 - 5.3 7.3 8.5 81 3.5 8.5 2.2 1 1 0 1 1 1 0 FYVE zinc finger zf-CCCH PF00642.24 KIK39990.1 - 2.3e-09 36.9 2.7 5.1e-09 35.8 2.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KIK39990.1 - 7.7e-08 32.1 5.0 1.4e-07 31.3 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK39990.1 - 8e-07 28.9 7.3 1.3e-06 28.2 7.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIK39990.1 - 1.8e-06 27.8 5.8 3.6e-06 26.9 5.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf_CCCH_4 PF18345.1 KIK39990.1 - 1.3e-05 25.1 4.4 3.2e-05 23.8 4.4 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4 PF00097.25 KIK39990.1 - 3.6e-05 23.5 8.6 6.7e-05 22.7 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK39990.1 - 6.1e-05 22.8 7.6 0.00012 21.9 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KIK39990.1 - 0.00036 20.6 3.6 0.00079 19.5 3.6 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 KIK39990.1 - 0.00069 19.9 6.0 0.0013 19.0 6.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-CCCH_4 PF18044.1 KIK39990.1 - 0.0012 18.5 2.9 0.0032 17.2 2.9 1.8 1 0 0 1 1 1 1 CCCH-type zinc finger zf-C3HC4_4 PF15227.6 KIK39990.1 - 0.0061 16.7 7.2 0.014 15.5 7.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RanBP PF00641.18 KIK39990.1 - 0.051 12.9 0.7 0.13 11.6 0.7 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Prok-RING_4 PF14447.6 KIK39990.1 - 0.14 12.0 6.0 0.26 11.2 6.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KIK39990.1 - 0.19 11.6 1.4 0.35 10.7 1.4 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.12 KIK39990.1 - 0.51 9.6 3.3 0.22 10.9 0.4 1.8 2 0 0 2 2 2 0 Rtf2 RING-finger Voltage_CLC PF00654.20 KIK39991.1 - 4.2e-89 299.2 38.2 6.6e-89 298.6 38.2 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 KIK39991.1 - 3.5e-08 33.8 0.1 0.00088 19.7 0.0 2.9 2 0 0 2 2 2 2 CBS domain LysM PF01476.20 KIK39995.1 - 6.2e-09 35.8 0.0 1.6e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 LysM domain GAF_2 PF13185.6 KIK39996.1 - 0.00014 22.1 0.0 0.0002 21.6 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KIK39996.1 - 0.0012 19.4 0.0 0.0017 19.0 0.0 1.3 1 0 0 1 1 1 1 GAF domain tRNA-synt_1e PF01406.19 KIK39997.1 - 4.5e-128 426.8 2.5 8.7e-128 425.9 0.0 2.3 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KIK39997.1 - 1.8e-08 33.5 0.7 7.9e-05 21.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 KIK39997.1 - 1.1e-05 25.9 0.0 4e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 DALR domain tRNA-synt_1 PF00133.22 KIK39997.1 - 0.00014 20.3 0.0 0.011 14.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Gti1_Pac2 PF09729.9 KIK39998.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family Gti1_Pac2 PF09729.9 KIK40000.1 - 9.4e-22 78.0 0.0 5.3e-19 69.0 0.0 2.3 1 1 1 2 2 2 2 Gti1/Pac2 family TFIIA PF03153.13 KIK40001.1 - 4.3e-56 191.7 0.0 5.2e-36 125.5 0.0 2.1 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF3844 PF12955.7 KIK40002.1 - 2.1e-29 101.7 5.7 3.1e-29 101.2 5.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.13 KIK40002.1 - 1.4 9.4 6.6 2.8 8.4 6.6 1.6 1 1 0 1 1 1 0 EGF-like domain TPR_10 PF13374.6 KIK40003.1 - 9.9e-31 104.7 27.9 0.0001 22.0 0.1 10.8 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.6 KIK40003.1 - 1.3e-13 51.0 22.1 0.66 10.3 0.0 12.1 8 2 5 13 13 13 5 Tetratricopeptide repeat TPR_7 PF13176.6 KIK40003.1 - 5.5e-07 29.2 3.0 4.3 7.6 0.0 7.8 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK40003.1 - 7.2e-06 26.4 23.2 30 5.8 0.1 10.0 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK40003.1 - 3.5e-05 23.7 0.1 52 4.4 0.0 7.9 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK40003.1 - 0.00014 21.7 14.4 9.8 6.6 0.1 8.9 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK40003.1 - 0.00077 19.1 1.3 46 3.8 0.0 6.5 8 0 0 8 8 8 0 TPR repeat TPR_1 PF00515.28 KIK40003.1 - 0.00095 18.9 9.1 3.4 7.6 0.1 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat T3SS_ATPase_C PF18269.1 KIK40003.1 - 0.0018 18.1 7.3 28 4.7 0.0 6.6 7 0 0 7 7 7 0 T3SS EscN ATPase C-terminal domain TPR_17 PF13431.6 KIK40003.1 - 0.004 17.4 6.7 51 4.6 0.0 7.1 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK40003.1 - 0.024 15.3 13.7 25 5.6 0.1 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat AMP-binding PF00501.28 KIK40006.1 - 2e-22 79.4 0.0 2.3e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.13 KIK40006.1 - 0.0053 15.7 0.0 0.0075 15.2 0.0 1.1 1 0 0 1 1 1 1 GH3 auxin-responsive promoter PPR_2 PF13041.6 KIK40007.1 - 7.9e-36 122.0 0.0 2.7e-07 30.7 0.0 8.2 5 2 3 8 8 8 6 PPR repeat family PPR_1 PF12854.7 KIK40007.1 - 6.2e-28 96.2 0.0 9.9e-09 34.8 0.0 6.9 8 0 0 8 8 8 4 PPR repeat PPR PF01535.20 KIK40007.1 - 1.3e-26 90.9 2.9 5.3e-08 32.6 0.0 7.2 7 0 0 7 7 7 5 PPR repeat PPR_3 PF13812.6 KIK40007.1 - 2.4e-23 82.0 0.0 4.6e-06 26.6 0.0 6.5 4 2 2 6 6 6 6 Pentatricopeptide repeat domain PPR_long PF17177.4 KIK40007.1 - 1.2e-09 37.8 0.1 0.07 12.5 0.0 4.4 4 1 1 5 5 5 3 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KIK40007.1 - 2.8e-06 27.7 1.8 2.5 9.2 0.0 6.3 4 1 2 6 6 6 1 Tetratricopeptide repeat ATP13 PF12921.7 KIK40007.1 - 0.0097 15.8 0.0 9.1 6.2 0.0 4.4 4 1 0 5 5 5 1 Mitochondrial ATPase expression DUF3368 PF11848.8 KIK40007.1 - 0.061 13.1 0.1 7.5 6.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3368) TPR_4 PF07721.14 KIK40007.1 - 0.51 11.1 4.3 59 4.7 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Hap4_Hap_bind PF10297.9 KIK40008.1 - 5.2e-09 35.9 3.6 1.2e-08 34.7 3.6 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 KIK40008.1 - 6.6e-06 26.1 15.5 0.00094 19.2 3.6 2.4 2 0 0 2 2 2 2 bZIP transcription factor NUDE_C PF04880.13 KIK40008.1 - 0.0015 19.1 12.0 0.0015 19.1 12.0 3.1 1 1 2 3 3 3 1 NUDE protein, C-terminal conserved region DUF572 PF04502.13 KIK40008.1 - 0.044 13.4 7.8 0.068 12.8 7.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3584 PF12128.8 KIK40008.1 - 0.067 10.7 8.3 0.09 10.3 8.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HAUS-augmin3 PF14932.6 KIK40008.1 - 0.097 12.2 5.5 0.16 11.6 5.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 YabA PF06156.13 KIK40008.1 - 0.35 11.5 5.5 0.78 10.4 5.5 1.5 1 0 0 1 1 1 0 Initiation control protein YabA TMF_DNA_bd PF12329.8 KIK40008.1 - 0.67 10.0 9.8 1.8 8.6 9.8 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding bZIP_2 PF07716.15 KIK40008.1 - 1.3 9.1 24.0 1.4 9.1 5.0 3.1 2 1 1 3 3 3 0 Basic region leucine zipper PMAIP1 PF15150.6 KIK40008.1 - 2.4 8.1 6.9 15 5.6 0.2 2.7 2 0 0 2 2 2 0 Phorbol-12-myristate-13-acetate-induced ZapB PF06005.12 KIK40008.1 - 6.4 7.3 12.7 9.9 6.7 11.5 2.0 1 1 1 2 2 2 0 Cell division protein ZapB HALZ PF02183.18 KIK40008.1 - 7 7.0 6.7 0.64 10.3 1.8 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper eIF2A PF08662.11 KIK40009.1 - 4.2e-40 137.7 1.2 3.3e-37 128.3 0.0 4.4 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KIK40009.1 - 5.9e-05 23.3 0.2 33 4.9 0.0 5.5 5 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 KIK40009.1 - 0.0019 18.0 2.4 0.0024 17.7 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KIK40009.1 - 0.0035 18.2 1.9 1.3 10.0 0.0 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat Sugar_tr PF00083.24 KIK40010.1 - 1.2e-46 159.5 26.5 1.7e-44 152.5 26.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK40010.1 - 1.4e-18 67.0 37.7 5.3e-10 38.8 16.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DMT_YdcZ PF04657.13 KIK40010.1 - 0.046 14.0 22.7 0.055 13.7 3.7 3.9 4 0 0 4 4 4 0 Putative inner membrane exporter, YdcZ DUF751 PF05421.11 KIK40010.1 - 2.3 9.0 7.2 1.8 9.3 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF751) SLS PF14611.6 KIK40011.1 - 4.2e-13 49.6 0.4 7.2e-13 48.9 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Spb1_C PF07780.12 KIK40012.1 - 2.2e-79 266.0 21.7 2.2e-79 266.0 21.7 3.3 4 0 0 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 KIK40012.1 - 1.2e-56 191.6 0.1 4.1e-56 189.9 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KIK40012.1 - 5.1e-47 159.7 5.6 5.1e-47 159.7 5.6 5.5 5 1 1 6 6 6 1 Domain of unknown function (DUF3381) DUF423 PF04241.15 KIK40013.1 - 9.5e-20 70.6 2.9 1.2e-19 70.3 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF423) MMPL PF03176.15 KIK40013.1 - 0.19 10.6 2.0 0.24 10.3 2.0 1.1 1 0 0 1 1 1 0 MMPL family zf-BED PF02892.15 KIK40014.1 - 0.18 11.8 0.3 3.1 7.9 0.1 2.6 2 0 0 2 2 2 0 BED zinc finger Ras PF00071.22 KIK40015.1 - 5.3e-54 182.2 0.0 6e-54 182.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK40015.1 - 4.8e-21 75.2 0.0 6.8e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK40015.1 - 1.9e-06 27.4 0.0 2.9e-06 26.8 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIK40015.1 - 0.0059 16.2 0.0 0.022 14.3 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Fungal_trans PF04082.18 KIK40016.1 - 1.5e-10 40.6 0.1 2.7e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK40016.1 - 5.5e-07 29.6 12.7 1.1e-06 28.6 12.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran_CTD PF16326.5 KIK40016.1 - 0.31 11.3 0.9 0.7 10.2 0.1 1.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain PDT PF00800.18 KIK40017.1 - 2.9e-49 167.4 0.0 4.2e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase p450 PF00067.22 KIK40018.1 - 8.5e-67 225.9 0.0 1.1e-66 225.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-CCCH PF00642.24 KIK40019.1 - 2.7e-14 52.6 13.7 1.1e-05 25.2 0.6 3.5 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIK40019.1 - 2.1e-11 43.5 21.1 4.7e-07 29.7 2.1 3.5 3 0 0 3 3 3 3 Zinc finger domain Torus PF16131.5 KIK40019.1 - 3.9e-06 27.5 14.3 0.0002 22.0 0.4 3.7 1 1 3 4 4 4 2 Torus domain zf-CCCH_4 PF18044.1 KIK40019.1 - 1.1e-05 25.1 0.4 1.1e-05 25.1 0.4 4.0 4 0 0 4 4 4 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KIK40019.1 - 0.00037 20.9 11.9 0.0038 17.7 0.3 3.2 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KIK40019.1 - 0.063 13.5 11.6 1.3 9.2 0.5 3.1 1 1 2 3 3 3 0 Zinc-finger containing family UPF0047 PF01894.17 KIK40020.1 - 7.1e-30 103.5 0.1 8.2e-30 103.3 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Fungal_trans PF04082.18 KIK40022.1 - 5.2e-10 38.8 0.0 9.7e-10 37.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK40022.1 - 2.7e-06 27.4 11.2 5.8e-06 26.3 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RhoGEF PF00621.20 KIK40024.1 - 3.1e-16 60.1 0.0 5.7e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain Exo_endo_phos PF03372.23 KIK40025.1 - 3.7e-20 72.4 0.0 2.2e-19 69.9 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M16_C PF05193.21 KIK40026.1 - 1.4e-14 54.5 0.0 1.2e-09 38.4 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KIK40026.1 - 3.8e-12 46.4 0.2 2.8e-10 40.3 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 KIK40026.1 - 0.00056 19.1 1.4 0.02 14.0 1.4 2.4 1 1 0 1 1 1 1 Peptidase M16C associated PGA2 PF07543.12 KIK40026.1 - 0.051 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 THDPS_N PF14790.6 KIK40026.1 - 0.086 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal NUFIP1 PF10453.9 KIK40027.1 - 3.8e-16 58.7 0.2 7e-16 57.8 0.2 1.5 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Sina PF03145.16 KIK40027.1 - 0.007 16.3 0.1 0.014 15.3 0.1 1.4 1 0 0 1 1 1 1 Seven in absentia protein family ERCC3_RAD25_C PF16203.5 KIK40028.1 - 0.039 13.1 0.0 0.044 13.0 0.0 1.1 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Rsm22 PF09243.10 KIK40028.1 - 0.12 11.6 0.1 0.14 11.4 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Plavaka PF18759.1 KIK40029.1 - 7.9e-42 143.6 0.8 9.9e-42 143.3 0.8 1.1 1 0 0 1 1 1 1 Plavaka transposase GrpB PF04229.14 KIK40030.1 - 0.12 12.6 0.0 0.12 12.6 0.0 1.0 1 0 0 1 1 1 0 GrpB protein Self-incomp_S1 PF05938.11 KIK40036.1 - 0.074 13.6 0.1 0.089 13.4 0.1 1.2 1 0 0 1 1 1 0 Plant self-incompatibility protein S1 F-box-like PF12937.7 KIK40044.1 - 2.1e-08 34.0 3.6 1.2e-07 31.5 3.6 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK40044.1 - 0.25 11.3 3.2 6.1 6.8 2.3 2.8 2 1 0 2 2 2 0 F-box domain SNF2_N PF00176.23 KIK40045.1 - 1.1e-55 188.8 0.0 2e-55 187.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK40045.1 - 2.6e-18 66.4 0.0 2.4e-17 63.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PHD PF00628.29 KIK40045.1 - 0.00012 21.9 17.9 0.00018 21.3 2.7 3.1 3 0 0 3 3 3 2 PHD-finger DEAD PF00270.29 KIK40045.1 - 0.0016 18.3 0.0 0.0053 16.6 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase NOA36 PF06524.12 KIK40045.1 - 0.17 11.2 8.4 0.43 9.9 8.4 1.8 1 0 0 1 1 1 0 NOA36 protein C1_1 PF00130.22 KIK40045.1 - 1.6 8.7 21.2 0.48 10.4 2.3 3.2 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 KIK40045.1 - 5.3 6.6 12.1 8.6 5.9 2.1 3.4 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain CsbD PF05532.12 KIK40046.1 - 0.062 13.2 0.7 0.062 13.2 0.7 2.6 2 0 0 2 2 2 0 CsbD-like NAR PF16251.5 KIK40048.1 - 0.017 15.8 0.0 0.02 15.6 0.0 1.1 1 0 0 1 1 1 0 Nucleic acid-binding domain (NAR) Gti1_Pac2 PF09729.9 KIK40049.1 - 1.8e-29 103.2 0.3 8.3e-27 94.4 0.1 2.5 2 1 1 3 3 3 2 Gti1/Pac2 family zf-MYND PF01753.18 KIK40051.1 - 8.3e-11 41.8 18.6 1.4e-10 41.1 18.6 1.4 1 0 0 1 1 1 1 MYND finger Ank_4 PF13637.6 KIK40051.1 - 1.9e-10 41.0 0.4 0.034 14.7 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK40051.1 - 2e-09 37.9 0.0 2e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIK40051.1 - 6.4e-09 35.9 0.0 4.6e-05 23.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KIK40051.1 - 1.7e-07 31.4 4.4 0.00025 21.4 0.3 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KIK40051.1 - 7.2e-06 26.0 0.6 0.14 12.8 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat Ecl1 PF12855.7 KIK40051.1 - 0.0025 19.0 2.3 0.0036 18.5 2.3 1.2 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-C6H2 PF15801.5 KIK40051.1 - 3.1 8.2 15.5 6.7 7.1 15.5 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-CCHC_4 PF14392.6 KIK40053.1 - 0.55 10.0 0.1 0.55 10.0 0.1 2.9 3 0 0 3 3 3 0 Zinc knuckle RVT_1 PF00078.27 KIK40055.1 - 2.4e-08 33.7 0.0 2.7e-08 33.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 KIK40057.1 - 7.4e-05 23.4 0.4 0.00012 22.7 0.4 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-4CXXC_R1 PF10497.9 KIK40058.1 - 0.038 14.2 0.5 0.05 13.8 0.5 1.2 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 PAAR_motif PF05488.13 KIK40058.1 - 0.061 13.5 0.2 0.095 12.9 0.2 1.3 1 0 0 1 1 1 0 PAAR motif DUF4675 PF15720.5 KIK40059.1 - 0.049 13.4 0.1 0.063 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4675) FolB PF02152.18 KIK40060.1 - 4.7e-31 107.6 1.3 1.3e-18 67.6 0.1 2.1 2 0 0 2 2 2 2 Dihydroneopterin aldolase Methyltransf_22 PF13383.6 KIK40062.1 - 2.9e-23 82.7 0.3 3.8e-23 82.3 0.3 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KIK40062.1 - 3.6e-10 40.1 0.0 5.6e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF4542 PF15075.6 KIK40062.1 - 0.045 14.1 0.0 0.43 11.0 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4542) DUF3552 PF12072.8 KIK40063.1 - 0.0011 18.5 11.9 0.0013 18.2 11.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF4691 PF15762.5 KIK40063.1 - 6.1 7.0 9.6 17 5.5 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4691) MIG-14_Wnt-bd PF06664.12 KIK40064.1 - 0.001 18.4 4.4 0.001 18.4 4.4 1.9 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion DUF2583 PF10762.9 KIK40064.1 - 0.03 14.7 2.2 0.07 13.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) Colicin_V PF02674.16 KIK40064.1 - 0.03 14.3 14.8 2.3 8.2 4.4 2.9 1 1 0 2 2 2 0 Colicin V production protein UL45 PF05473.12 KIK40064.1 - 0.09 12.4 0.4 0.15 11.7 0.4 1.4 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like DUF373 PF04123.13 KIK40064.1 - 0.31 10.4 3.8 0.92 8.9 4.3 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF3593 PF12159.8 KIK40064.1 - 0.61 10.2 8.2 0.17 12.0 0.4 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3593) p450 PF00067.22 KIK40065.1 - 3.1e-72 243.8 0.1 4.1e-72 243.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK40066.1 - 1.9e-72 244.5 0.0 2.6e-72 244.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.23 KIK40067.1 - 2e-44 152.3 28.0 3.9e-26 92.3 5.8 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KIK40067.1 - 2.5e-20 73.4 0.0 4.8e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIK40067.1 - 0.00023 21.1 0.2 0.14 12.0 0.2 2.6 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIK40067.1 - 0.00038 21.0 0.1 0.00073 20.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KIK40067.1 - 0.006 15.7 0.6 0.015 14.3 0.2 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 KIK40067.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIK40067.1 - 0.098 13.0 0.0 0.33 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KIK40067.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain EI24 PF07264.11 KIK40070.1 - 2.5e-09 37.6 1.4 3.7e-09 37.1 1.4 1.4 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Peptidase_S10 PF00450.22 KIK40071.1 - 2.5e-103 346.7 0.0 3.2e-103 346.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Pkinase_Tyr PF07714.17 KIK40073.1 - 1.6e-39 135.8 0.0 2.3e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK40073.1 - 7.9e-34 117.2 0.0 1.1e-33 116.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK40073.1 - 0.0038 17.2 0.0 0.0054 16.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KIK40073.1 - 0.041 13.2 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIK40073.1 - 0.042 13.5 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family WD40 PF00400.32 KIK40074.1 - 1.6e-21 76.2 8.8 7.3e-06 26.6 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40074.1 - 0.00026 21.2 0.0 0.98 9.8 0.0 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK40074.1 - 0.00047 19.2 0.1 0.49 9.3 0.1 2.2 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK40074.1 - 0.00088 18.0 0.0 0.23 10.1 0.0 2.7 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Pkinase_Tyr PF07714.17 KIK40077.1 - 5.7e-36 124.1 0.0 7e-36 123.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK40077.1 - 1.7e-31 109.5 0.0 2.1e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK40077.1 - 6.7e-06 25.1 0.0 8.6e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK40077.1 - 0.0095 15.9 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK40077.1 - 0.013 15.1 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family WD40 PF00400.32 KIK40078.1 - 1.3e-11 44.8 0.9 0.0002 22.1 0.1 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40078.1 - 1.1e-05 25.6 0.1 0.023 15.0 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KIK40078.1 - 0.043 13.4 0.1 0.053 13.1 0.1 1.1 1 0 0 1 1 1 0 PQQ-like domain Ribosomal_L13 PF00572.18 KIK40079.1 - 1.1e-49 167.8 0.3 1.5e-49 167.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 AAA_23 PF13476.6 KIK40081.1 - 1.2e-19 71.7 11.7 4.6e-18 66.4 11.7 2.4 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 KIK40081.1 - 1.9e-11 43.8 0.0 4.5e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KIK40081.1 - 9.3e-05 22.3 0.0 0.0004 20.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KIK40081.1 - 0.00092 18.9 0.2 0.0052 16.5 0.0 2.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KIK40081.1 - 0.022 14.5 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_21 PF13304.6 KIK40081.1 - 0.086 12.6 4.1 0.092 12.5 0.1 2.5 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KIK40081.1 - 0.12 12.7 0.0 0.38 11.2 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 KIK40081.1 - 0.13 11.8 0.0 0.13 11.8 0.0 3.0 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 KIK40081.1 - 0.28 11.7 9.6 17 5.9 9.6 2.9 1 1 0 1 1 1 0 ABC transporter PCRF PF03462.18 KIK40081.1 - 1.4 8.8 11.9 0.14 12.0 6.2 2.1 2 0 0 2 2 2 0 PCRF domain Occludin_ELL PF07303.13 KIK40081.1 - 4.2 8.2 17.9 3.6 8.4 10.3 2.9 2 1 0 2 2 2 0 Occludin homology domain SMC_N PF02463.19 KIK40082.1 - 4.3e-06 26.3 4.7 6.4e-06 25.8 4.7 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Fib_alpha PF08702.10 KIK40082.1 - 0.3 11.3 22.2 0.21 11.8 5.5 4.0 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Sec20 PF03908.13 KIK40082.1 - 1.5 8.8 6.5 4.3 7.3 0.3 3.5 3 0 0 3 3 3 0 Sec20 TcpS PF17456.2 KIK40082.1 - 1.5 8.9 8.1 0.51 10.4 0.1 3.0 2 1 0 2 2 2 0 Toxin-coregulated pilus protein S Semialdhyde_dhC PF02774.18 KIK40083.1 - 4.6e-37 127.9 0.0 7.7e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KIK40083.1 - 2.3e-28 99.1 0.0 3.6e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KIK40083.1 - 0.012 15.8 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 KIK40083.1 - 0.067 13.9 0.0 0.15 12.8 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 KIK40083.1 - 0.097 12.8 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Rab5ip PF07019.12 KIK40084.1 - 1e-20 74.1 3.3 1.3e-20 73.8 3.3 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) TPR_1 PF00515.28 KIK40086.1 - 5.7e-12 44.9 0.0 0.0025 17.5 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK40086.1 - 1.1e-11 43.9 0.3 0.00054 19.9 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK40086.1 - 3.4e-09 36.7 1.6 0.23 12.4 0.0 7.8 5 3 3 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK40086.1 - 1.5e-08 34.4 0.0 0.089 13.2 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK40086.1 - 8.9e-08 31.8 0.8 0.024 14.8 0.0 5.3 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK40086.1 - 9.2e-07 29.1 0.1 0.052 13.9 0.0 4.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK40086.1 - 1.4e-06 28.7 0.0 0.84 10.2 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK40086.1 - 5.5e-06 26.9 0.1 0.0011 19.6 0.0 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIK40086.1 - 3e-05 24.1 2.5 0.00072 19.7 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK40086.1 - 3.2e-05 23.7 4.4 6.3 7.1 0.0 6.8 5 2 2 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK40086.1 - 3.2e-05 23.5 0.0 0.13 11.9 0.0 3.7 2 1 1 3 3 3 2 TPR repeat ANAPC3 PF12895.7 KIK40086.1 - 0.00025 21.2 0.0 0.0031 17.7 0.0 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KIK40086.1 - 0.014 16.0 0.0 8.3 7.3 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIK40086.1 - 0.13 12.1 7.5 13 5.8 0.0 5.7 6 1 1 7 7 7 0 Tetratricopeptide repeat HA2 PF04408.23 KIK40087.1 - 2.6e-20 72.7 0.0 5.6e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KIK40087.1 - 2.9e-14 53.4 0.0 8.3e-14 51.9 0.0 1.8 1 1 1 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK40087.1 - 1.2e-07 31.7 0.0 2.2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KIK40087.1 - 2.1e-06 28.0 0.1 8.7e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KIK40087.1 - 6.8e-05 23.2 0.0 0.00019 21.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KIK40087.1 - 0.012 15.6 0.0 0.08 12.9 0.0 2.2 2 0 0 2 2 2 0 Flavivirus DEAD domain ABC_tran PF00005.27 KIK40087.1 - 0.016 15.8 0.4 0.92 10.0 0.2 2.5 1 1 1 2 2 2 0 ABC transporter AAA_30 PF13604.6 KIK40087.1 - 0.018 14.8 0.1 0.037 13.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KIK40087.1 - 0.052 12.9 0.3 0.21 10.9 0.0 2.1 3 0 0 3 3 3 0 KaiC T2SSE PF00437.20 KIK40087.1 - 0.056 12.5 0.1 0.098 11.7 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KIK40087.1 - 0.083 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 KIK40087.1 - 0.091 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ham1p_like PF01725.16 KIK40088.1 - 6.9e-55 185.9 0.0 7.8e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Ham1 family SH3_1 PF00018.28 KIK40089.1 - 5.6e-14 51.5 0.4 1.2e-13 50.4 0.4 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK40089.1 - 6.2e-14 51.6 0.1 1.3e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 KIK40089.1 - 1.7e-13 50.4 0.0 3.9e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 KIK40089.1 - 1.5e-12 47.9 0.1 3.6e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 PH domain SAM_1 PF00536.30 KIK40089.1 - 3.7e-12 46.5 0.2 1.2e-11 44.8 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 KIK40089.1 - 2e-07 30.5 0.0 3.9e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_3 PF18016.1 KIK40089.1 - 0.0066 16.2 0.0 0.02 14.7 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 KIK40089.1 - 0.0072 16.5 0.2 0.018 15.3 0.2 1.6 1 0 0 1 1 1 1 Ste50p, sterile alpha motif PH_11 PF15413.6 KIK40089.1 - 1.8 9.1 3.9 5.7 7.4 2.2 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain 4HBT PF03061.22 KIK40090.1 - 0.00037 20.8 0.1 0.00092 19.5 0.1 1.7 1 1 0 1 1 1 1 Thioesterase superfamily 4HBT PF03061.22 KIK40092.1 - 2.6e-08 34.1 0.1 5.2e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Thioesterase superfamily His_Phos_1 PF00300.22 KIK40093.1 - 1.3e-10 41.3 0.5 2.7e-10 40.3 0.5 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 2OG-FeII_Oxy_2 PF13532.6 KIK40094.1 - 6.8e-12 46.0 0.0 8.7e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ubiquitin PF00240.23 KIK40095.1 - 4.9e-25 87.1 0.2 5.3e-25 87.0 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KIK40095.1 - 5.7e-13 48.5 0.5 6.2e-13 48.4 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KIK40095.1 - 8.4e-05 22.4 0.0 9.3e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 KIK40095.1 - 0.0001 22.7 0.0 0.00021 21.7 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KIK40095.1 - 0.03 14.7 0.1 0.037 14.4 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain Cu_amine_oxid PF01179.20 KIK40096.1 - 2.4e-124 415.4 0.0 3.3e-124 414.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 KIK40096.1 - 6.5e-08 32.2 0.1 1.8e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 KIK40096.1 - 0.0017 18.5 0.0 0.0046 17.2 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxid PF01179.20 KIK40097.1 - 2.6e-124 415.3 0.3 3.4e-124 414.9 0.3 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 KIK40097.1 - 6.5e-07 29.0 0.0 2e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 KIK40097.1 - 0.081 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain PI3Ka PF00613.20 KIK40099.1 - 1e-54 184.8 0.2 1.6e-54 184.1 0.2 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KIK40099.1 - 4e-48 164.4 0.0 3.9e-33 115.3 0.0 2.7 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KIK40099.1 - 1.9e-39 134.7 0.0 4.1e-39 133.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 adh_short PF00106.25 KIK40102.1 - 7.4e-47 159.3 0.1 9.6e-47 159.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK40102.1 - 2.8e-39 135.1 0.0 3.4e-39 134.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK40102.1 - 1e-07 32.0 0.0 6.7e-07 29.4 0.0 2.0 1 1 1 2 2 2 1 KR domain DUF1776 PF08643.10 KIK40102.1 - 3.7e-07 29.8 0.0 5.4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KIK40102.1 - 0.0047 16.4 0.0 0.024 14.1 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1295 PF06966.12 KIK40103.1 - 1.7e-32 112.8 6.2 1.2e-31 110.0 6.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KIK40103.1 - 0.025 15.0 0.0 0.091 13.2 0.0 1.9 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Sde2_N_Ubi PF13019.6 KIK40104.1 - 1.1e-46 158.7 0.4 1.1e-46 158.7 0.4 1.5 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain DUF3829 PF12889.7 KIK40104.1 - 0.043 13.3 4.3 0.057 12.9 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Aconitase PF00330.20 KIK40105.1 - 1e-110 371.0 0.3 9e-110 367.8 0.3 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KIK40105.1 - 5.1e-20 72.1 0.0 9.7e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KIK40105.1 - 0.0023 16.7 0.0 0.0036 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) Aconitase_2_N PF06434.13 KIK40105.1 - 0.1 12.2 0.0 0.65 9.6 0.0 2.1 2 0 0 2 2 2 0 Aconitate hydratase 2 N-terminus MCM PF00493.23 KIK40105.1 - 0.2 10.7 0.7 0.75 8.9 0.4 1.9 2 1 0 2 2 2 0 MCM P-loop domain TauD PF02668.16 KIK40106.1 - 8.9e-38 130.6 0.0 1.3e-37 130.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KIK40106.1 - 2.2e-17 63.4 0.1 8.3e-17 61.6 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 KIK40106.1 - 0.015 14.5 0.0 0.085 12.0 0.0 1.9 2 0 0 2 2 2 0 CsiD Aldedh PF00171.22 KIK40107.1 - 1.9e-181 603.6 0.2 2.2e-181 603.4 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIK40107.1 - 0.00031 19.9 0.0 0.00044 19.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF2370 PF10176.9 KIK40108.1 - 5.7e-62 209.3 0.1 4.4e-61 206.4 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) TFIIIC_sub6 PF10419.9 KIK40109.1 - 1.3e-17 63.4 0.0 2.1e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain O-FucT PF10250.9 KIK40111.1 - 2.1e-09 37.5 0.0 7.4e-09 35.8 0.0 1.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase ANAPC4_WD40 PF12894.7 KIK40113.1 - 0.015 15.6 0.2 0.36 11.2 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK40113.1 - 0.2 12.6 18.5 4.2 8.4 0.1 6.2 7 0 0 7 7 7 0 WD domain, G-beta repeat SH3_9 PF14604.6 KIK40116.1 - 0.00099 18.9 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIK40116.1 - 0.028 14.0 0.0 0.085 12.5 0.0 1.7 2 0 0 2 2 2 0 SH3 domain Gram_pos_anchor PF00746.21 KIK40116.1 - 0.33 10.9 2.2 0.67 10.0 2.2 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif SPX PF03105.19 KIK40116.1 - 4.3 7.2 5.3 5.2 6.9 5.3 1.2 1 0 0 1 1 1 0 SPX domain Actin PF00022.19 KIK40120.1 - 1.6e-86 290.4 0.0 3.8e-85 286.0 0.0 2.0 1 1 0 1 1 1 1 Actin Fungal_trans PF04082.18 KIK40123.1 - 8.8e-09 34.8 0.4 4.1e-08 32.6 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK40123.1 - 0.00015 21.8 9.1 0.00025 21.1 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YL1 PF05764.13 KIK40123.1 - 0.65 10.1 3.8 1.3 9.1 3.8 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Acyl-CoA_dh_1 PF00441.24 KIK40124.1 - 1.3e-29 103.4 1.7 2.1e-29 102.7 1.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIK40124.1 - 3.2e-21 75.3 0.6 6.1e-21 74.4 0.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KIK40124.1 - 3e-16 59.3 0.0 6.8e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KIK40124.1 - 1.6e-14 54.5 0.0 4.1e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KIK40124.1 - 2.3e-05 24.7 0.4 5.1e-05 23.6 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KIK40124.1 - 0.17 11.5 0.6 0.37 10.4 0.0 1.8 2 1 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal WD40 PF00400.32 KIK40125.1 - 4e-34 116.1 15.9 1.2e-05 26.0 0.0 8.3 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40125.1 - 3.3e-12 46.5 0.4 0.024 14.9 0.1 5.6 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK40125.1 - 0.00047 20.1 0.0 0.72 9.7 0.0 3.2 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK40125.1 - 0.017 15.1 0.9 7.3 6.7 0.0 4.5 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Big_7 PF17957.1 KIK40125.1 - 0.037 14.8 0.1 29 5.5 0.0 3.4 3 0 0 3 3 3 0 Bacterial Ig domain Nup160 PF11715.8 KIK40125.1 - 0.04 12.6 0.1 0.21 10.2 0.0 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK40125.1 - 0.055 12.4 1.7 0.37 9.7 0.4 2.9 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_21 PF09976.9 KIK40125.1 - 0.082 12.6 0.2 0.082 12.6 0.2 1.9 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_14 PF13428.6 KIK40125.1 - 0.13 13.1 2.8 3.6 8.7 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat O-FucT PF10250.9 KIK40127.1 - 7.4e-06 25.9 0.0 7.5e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase WD40 PF00400.32 KIK40131.1 - 5.1e-39 131.6 20.7 2.2e-07 31.4 1.8 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40131.1 - 6.9e-11 42.3 0.2 0.052 13.9 0.0 5.7 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK40131.1 - 1.4e-05 24.2 0.1 0.005 15.8 0.0 3.4 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK40131.1 - 2.4e-05 24.3 0.0 0.46 10.3 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK40131.1 - 0.02 14.8 0.4 23 5.1 0.0 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 KIK40131.1 - 0.067 11.9 0.0 5.9 5.5 0.0 2.8 1 1 0 2 2 2 0 Nup133 N terminal like HET PF06985.11 KIK40132.1 - 1.5e-09 38.3 3.5 3.3e-07 30.8 0.2 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NTP_transferase PF00483.23 KIK40138.1 - 1e-40 139.9 0.0 2.4e-40 138.7 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KIK40138.1 - 3.6e-06 27.4 0.2 1e-05 25.9 0.2 1.8 1 0 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.18 KIK40138.1 - 0.00033 20.6 0.1 0.00054 19.9 0.1 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase IspD PF01128.19 KIK40138.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Sugar_tr PF00083.24 KIK40141.1 - 9.8e-84 281.8 19.4 1.3e-83 281.4 19.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK40141.1 - 4.3e-18 65.4 46.5 3.2e-12 46.0 17.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.15 KIK40141.1 - 1.9 8.4 10.2 0.45 10.4 5.6 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain Aldo_ket_red PF00248.21 KIK40143.1 - 1.2e-46 159.3 0.0 2.7e-44 151.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Urease_linker PF18473.1 KIK40143.1 - 0.064 13.1 0.0 0.61 10.0 0.0 2.5 2 1 1 3 3 3 0 Urease subunit beta-alpha linker domain Peptidase_C12 PF01088.21 KIK40144.1 - 5.3e-53 179.9 0.0 8.3e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KIK40144.1 - 2.3e-15 56.2 0.4 4.2e-15 55.4 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Med31 PF05669.12 KIK40145.1 - 6.1e-36 122.3 8.5 7.4e-36 122.0 8.5 1.1 1 0 0 1 1 1 1 SOH1 TPT PF03151.16 KIK40146.1 - 1.2e-23 83.9 15.8 1.4e-23 83.7 15.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KIK40146.1 - 2.6e-05 24.4 37.9 0.0014 18.9 16.1 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KIK40146.1 - 0.00088 18.6 13.1 0.0041 16.4 12.9 1.8 1 1 0 1 1 1 1 UAA transporter family Zn_clus PF00172.18 KIK40148.1 - 2.5e-05 24.3 11.9 4.5e-05 23.5 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIK40148.1 - 0.0088 15.1 0.1 0.014 14.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain APG5 PF04106.12 KIK40149.1 - 9e-64 215.2 0.0 1.2e-63 214.7 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 ECH_1 PF00378.20 KIK40152.1 - 3.3e-60 203.5 0.6 3.9e-60 203.3 0.6 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIK40152.1 - 4.4e-31 108.6 0.4 5.5e-31 108.3 0.4 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KIK40152.1 - 0.028 14.4 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 Peptidase family S49 DUF202 PF02656.15 KIK40153.1 - 0.29 11.6 3.1 0.71 10.4 3.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Syndecan PF01034.20 KIK40153.1 - 0.66 9.9 5.8 0.6 10.1 0.2 2.3 2 0 0 2 2 2 0 Syndecan domain UPF0182 PF03699.13 KIK40153.1 - 0.68 8.0 3.2 0.77 7.8 3.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) MmgE_PrpD PF03972.14 KIK40155.1 - 5.6e-154 512.9 0.0 6.9e-154 512.6 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Rhodanese PF00581.20 KIK40156.1 - 1.7e-05 25.3 0.0 3.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain ATP-sulfurylase PF01747.17 KIK40158.1 - 8.3e-87 290.1 0.3 1.3e-86 289.5 0.3 1.3 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 KIK40158.1 - 1.7e-49 167.5 0.0 3.1e-49 166.7 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.20 KIK40158.1 - 2.3e-46 157.6 0.0 3.3e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase RNase_H2-Ydr279 PF09468.10 KIK40159.1 - 2.9e-17 63.3 0.1 5.7e-17 62.3 0.1 1.5 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KIK40159.1 - 1.3e-13 51.0 0.0 3.4e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain Slu7 PF11708.8 KIK40160.1 - 1.1e-107 359.8 13.9 1.1e-107 359.8 13.9 2.2 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KIK40160.1 - 0.14 11.9 0.3 0.28 11.0 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF1771 PF08590.10 KIK40161.1 - 0.23 11.9 3.1 0.38 11.2 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) NTP_transf_7 PF07984.12 KIK40162.1 - 0.021 14.1 0.1 0.86 8.8 0.0 2.1 2 0 0 2 2 2 0 Nucleotidyltransferase Mononeg_RNA_pol PF00946.19 KIK40162.1 - 0.04 11.6 0.0 0.049 11.3 0.0 1.0 1 0 0 1 1 1 0 Mononegavirales RNA dependent RNA polymerase KxDL PF10241.9 KIK40162.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein SNF2_N PF00176.23 KIK40163.1 - 5.5e-60 202.9 0.1 9.4e-60 202.2 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.6 KIK40163.1 - 1.2e-24 86.6 0.3 3.9e-24 84.9 0.3 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Chromo PF00385.24 KIK40163.1 - 1.3e-20 73.0 4.5 4.3e-15 55.3 0.2 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KIK40163.1 - 5.9e-18 65.2 0.0 1.4e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cdh1_DBD_1 PF18196.1 KIK40163.1 - 4.3e-08 33.5 1.0 4.3e-08 33.5 1.0 3.9 3 1 0 3 3 3 1 Chromodomain helicase DNA-binding domain 1 ResIII PF04851.15 KIK40163.1 - 2.5e-07 30.8 0.0 1.1e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDH1_2_SANT_HL1 PF18375.1 KIK40163.1 - 0.00034 21.2 1.7 0.0011 19.6 0.1 2.8 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 SWI2_SNF2 PF18766.1 KIK40163.1 - 0.0096 15.6 0.0 0.028 14.1 0.0 1.8 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Myb_DNA-binding PF00249.31 KIK40163.1 - 0.041 14.1 0.0 0.14 12.3 0.0 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain FlhC PF05280.11 KIK40163.1 - 0.08 12.7 0.2 0.24 11.1 0.1 1.8 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhC) PALP PF00291.25 KIK40164.1 - 1.4e-07 31.2 0.1 1.5e-07 31.1 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Tfb4 PF03850.14 KIK40166.1 - 7.9e-82 274.8 0.1 9.4e-82 274.6 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Olduvai PF06758.13 KIK40166.1 - 0.11 12.7 0.0 0.36 11.1 0.0 1.9 1 0 0 1 1 1 0 Olduvai domain Asparaginase_2 PF01112.18 KIK40167.1 - 1.8e-50 171.7 0.5 2.8e-50 171.1 0.5 1.3 1 0 0 1 1 1 1 Asparaginase p450 PF00067.22 KIK40168.1 - 1.4e-58 198.8 0.0 8.3e-58 196.2 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 GTP_cyclohydroI PF01227.22 KIK40168.1 - 0.13 11.7 0.0 0.51 9.7 0.0 1.9 2 0 0 2 2 2 0 GTP cyclohydrolase I TMF_DNA_bd PF12329.8 KIK40169.1 - 0.00013 21.9 8.3 0.00013 21.9 8.3 7.3 3 2 3 7 7 7 3 TATA element modulatory factor 1 DNA binding HMMR_C PF15908.5 KIK40169.1 - 0.00033 20.9 2.9 0.00033 20.9 2.9 4.8 3 2 2 5 5 5 1 Hyaluronan mediated motility receptor C-terminal Atg14 PF10186.9 KIK40169.1 - 0.0037 16.4 25.5 0.0037 16.4 25.5 3.5 2 1 0 3 3 3 1 Vacuolar sorting 38 and autophagy-related subunit 14 CHASE4 PF05228.13 KIK40169.1 - 0.015 15.5 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 CHASE4 domain NIF PF03031.18 KIK40170.1 - 1.2e-54 184.3 0.0 1.4e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 KIK40170.1 - 0.0063 16.9 0.1 0.12 12.7 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK40170.1 - 0.18 12.1 0.0 23 5.2 0.0 2.1 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase NAD_binding_4 PF07993.12 KIK40171.1 - 1.9e-41 141.9 0.0 3.8e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIK40171.1 - 4.7e-31 107.8 0.0 1.2e-30 106.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KIK40171.1 - 7.4e-12 45.4 0.0 2.1e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KIK40171.1 - 5.1e-09 35.9 0.0 9.4e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KIK40171.1 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 KR domain PLA2_B PF01735.18 KIK40172.1 - 5.7e-103 345.0 1.8 7.7e-103 344.5 1.8 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain VSP PF03302.13 KIK40172.1 - 0.00065 18.7 1.0 0.00065 18.7 1.0 2.2 3 0 0 3 3 3 1 Giardia variant-specific surface protein DUF4381 PF14316.6 KIK40172.1 - 0.089 13.0 0.2 0.18 12.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PTP_tm PF18861.1 KIK40172.1 - 0.15 12.0 4.1 0.22 11.5 1.7 2.2 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF5385 PF17359.2 KIK40172.1 - 0.33 10.5 0.0 0.5 9.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) SKG6 PF08693.10 KIK40172.1 - 5.6 6.5 7.3 13 5.3 7.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CHAT PF12770.7 KIK40174.1 - 6.8e-30 104.5 0.2 2.2e-29 102.8 0.0 1.9 2 0 0 2 2 2 1 CHAT domain TPR_10 PF13374.6 KIK40174.1 - 1.8e-13 49.9 5.7 0.014 15.2 0.0 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIK40174.1 - 3.9e-09 36.7 6.2 1.4 9.3 0.0 7.6 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 KIK40174.1 - 2.4e-06 27.1 0.7 1.6 8.7 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK40174.1 - 5.4e-05 23.0 3.3 27 5.2 0.0 7.4 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK40174.1 - 0.00011 21.9 3.1 13 6.1 0.0 6.4 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK40174.1 - 0.0034 18.1 14.8 16 6.6 0.0 8.6 8 1 1 9 9 9 1 Tetratricopeptide repeat MIT PF04212.18 KIK40174.1 - 0.14 12.3 0.2 9.2 6.4 0.0 3.5 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Vta1_C PF18097.1 KIK40174.1 - 0.2 11.4 7.9 0.28 10.9 0.0 4.7 5 0 0 5 5 5 0 Vta1 C-terminal domain CHAT PF12770.7 KIK40178.1 - 9.7e-29 100.7 0.3 5.7e-27 94.9 0.3 2.2 1 1 0 1 1 1 1 CHAT domain tRNA-synt_1d PF00750.19 KIK40179.1 - 7.6e-95 317.8 1.8 9.9e-95 317.4 1.8 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KIK40179.1 - 2.5e-19 69.6 0.0 5e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Syndecan PF01034.20 KIK40180.1 - 0.22 11.5 0.7 0.37 10.8 0.7 1.3 1 0 0 1 1 1 0 Syndecan domain DUF3218 PF11508.8 KIK40180.1 - 0.46 9.9 2.0 0.28 10.6 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3218) MatE PF01554.18 KIK40181.1 - 1.5e-52 177.5 27.9 1.4e-27 96.3 11.8 2.3 2 0 0 2 2 2 2 MatE YrhC PF14143.6 KIK40181.1 - 0.19 11.8 1.3 0.83 9.8 0.4 2.6 2 0 0 2 2 2 0 YrhC-like protein Iron_permease PF04120.12 KIK40181.1 - 0.37 10.6 3.1 0.8 9.5 0.1 2.3 2 0 0 2 2 2 0 Low affinity iron permease SKG6 PF08693.10 KIK40182.1 - 0.0036 16.7 0.9 0.0068 15.8 0.9 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.20 KIK40182.1 - 0.094 12.6 0.9 0.18 11.7 0.9 1.4 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.15 KIK40182.1 - 0.19 11.5 0.4 0.37 10.6 0.4 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Stevor PF17410.2 KIK40182.1 - 0.26 10.8 0.1 0.43 10.1 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame RIFIN PF02009.16 KIK40182.1 - 0.44 10.4 0.9 0.79 9.6 0.9 1.4 1 1 0 1 1 1 0 Rifin HMG_box PF00505.19 KIK40183.1 - 9.3e-13 48.4 0.1 2e-12 47.4 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK40183.1 - 0.00012 22.6 0.0 0.00026 21.5 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain IBR PF01485.21 KIK40187.1 - 6.8e-07 29.4 39.3 7.1e-06 26.2 6.8 3.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain TRAF6_Z2 PF18048.1 KIK40187.1 - 7.1 6.8 11.1 0.3 11.2 0.3 3.5 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 TPR_10 PF13374.6 KIK40192.1 - 1.2e-13 50.4 7.5 0.033 14.1 0.0 7.8 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIK40192.1 - 8.8e-11 42.0 5.6 0.025 14.9 0.0 7.5 3 2 2 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK40192.1 - 9.9e-09 34.7 6.2 0.13 12.1 0.1 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK40192.1 - 4.7e-08 32.6 4.8 0.37 11.0 0.1 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK40192.1 - 1.6e-06 27.8 0.0 0.26 11.6 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat MIT PF04212.18 KIK40192.1 - 4.8e-05 23.3 0.2 0.32 11.1 0.0 5.3 6 0 0 6 6 6 1 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 KIK40192.1 - 5.7e-05 22.9 8.0 1.4 9.1 0.0 6.2 6 2 0 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK40192.1 - 0.004 17.8 13.9 18 6.5 0.1 8.6 8 2 2 10 10 10 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK40192.1 - 0.0046 16.6 0.1 4.9 6.9 0.0 4.2 4 0 0 4 4 4 1 TPR repeat C2 PF00168.30 KIK40192.1 - 0.0051 17.1 0.0 0.0094 16.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain Dehydratase_SU PF02287.15 KIK40192.1 - 0.057 13.5 0.1 9.4 6.3 0.0 3.2 3 0 0 3 3 3 0 Dehydratase small subunit Vta1_C PF18097.1 KIK40192.1 - 0.33 10.7 9.5 1.5 8.6 0.0 5.0 5 0 0 5 5 5 0 Vta1 C-terminal domain CHAT PF12770.7 KIK40193.1 - 1.3e-32 113.4 0.0 1.6e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 CHAT domain Zeta_toxin PF06414.12 KIK40193.1 - 0.043 13.1 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin GP67 PF17634.2 KIK40196.1 - 0.0082 16.5 1.9 0.032 14.6 2.3 1.7 2 0 0 2 2 2 1 Gene product 67 WD40 PF00400.32 KIK40197.1 - 3e-11 43.7 1.1 0.00084 20.1 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat SGL PF08450.12 KIK40197.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region ANAPC4_WD40 PF12894.7 KIK40197.1 - 0.068 13.5 0.0 0.45 10.8 0.0 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK40197.1 - 0.11 12.4 0.2 3.3 7.8 0.0 3.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat FAD_binding_3 PF01494.19 KIK40199.1 - 8.4e-47 160.1 0.0 1.1e-29 103.8 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KIK40199.1 - 3.9e-08 32.9 1.7 0.00054 19.3 0.2 2.5 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIK40199.1 - 4.7e-07 29.0 0.3 0.00058 18.8 0.0 2.2 1 1 0 2 2 2 2 Tryptophan halogenase DAO PF01266.24 KIK40199.1 - 1.4e-05 24.8 1.2 0.002 17.8 0.4 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIK40199.1 - 5e-05 22.5 2.8 0.15 11.1 0.9 2.9 2 1 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 KIK40199.1 - 5.7e-05 22.0 0.5 0.21 10.2 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 KIK40199.1 - 0.00011 21.6 0.2 0.00047 19.5 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIK40199.1 - 0.00015 21.3 0.2 0.00025 20.5 0.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK40199.1 - 0.00057 19.1 0.8 0.0023 17.1 0.7 1.8 1 1 1 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KIK40199.1 - 0.0036 17.5 0.1 0.008 16.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIK40199.1 - 0.0065 15.7 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Thi4 family SE PF08491.10 KIK40199.1 - 0.022 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase NAD_binding_9 PF13454.6 KIK40199.1 - 0.052 13.5 0.3 0.44 10.5 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 KIK40199.1 - 0.1 11.6 1.1 0.19 10.8 1.1 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A ABC_tran PF00005.27 KIK40201.1 - 1.6e-43 148.5 0.1 1.3e-22 80.8 0.0 3.7 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 KIK40201.1 - 4e-17 63.0 3.3 0.00015 21.7 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIK40201.1 - 4.1e-09 36.2 0.2 0.03 13.8 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA PF00004.29 KIK40201.1 - 1.3e-07 32.1 0.3 0.034 14.6 0.0 3.6 3 2 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KIK40201.1 - 2.2e-07 30.9 0.0 0.019 14.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase ABC_tran_Xtn PF12848.7 KIK40201.1 - 2.5e-06 27.4 3.9 6.8e-06 26.0 3.9 1.8 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KIK40201.1 - 2.8e-06 27.6 2.2 0.18 12.1 0.2 3.7 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KIK40201.1 - 5.9e-06 26.8 0.3 0.11 12.9 0.2 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KIK40201.1 - 1.4e-05 25.7 0.2 0.061 13.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 KIK40201.1 - 3.7e-05 23.7 0.3 0.44 10.5 0.0 2.9 3 0 0 3 3 3 2 NACHT domain AAA_24 PF13479.6 KIK40201.1 - 0.0001 22.1 0.0 0.43 10.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KIK40201.1 - 0.00023 20.8 0.1 0.16 11.8 0.0 2.8 3 0 0 3 3 2 1 P-loop containing region of AAA domain ATPase_2 PF01637.18 KIK40201.1 - 0.00025 21.1 0.0 0.29 11.0 0.0 2.9 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KIK40201.1 - 0.0006 20.2 0.0 1.8 9.0 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 KIK40201.1 - 0.00083 19.4 0.1 4.2 7.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 KIK40201.1 - 0.00096 19.2 0.0 0.29 11.2 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 KIK40201.1 - 0.0014 18.4 0.1 0.17 11.5 0.1 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 KIK40201.1 - 0.0016 18.5 3.1 1.7 8.7 0.1 3.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KIK40201.1 - 0.0016 17.9 0.1 1.1 8.5 0.0 2.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_15 PF13175.6 KIK40201.1 - 0.0018 18.1 0.0 1.7 8.3 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 KIK40201.1 - 0.0019 18.5 0.3 0.04 14.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 KIK40201.1 - 0.0024 18.1 0.0 4.9 7.4 0.0 3.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DAP3 PF10236.9 KIK40201.1 - 0.0036 16.5 0.1 1.1 8.3 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_25 PF13481.6 KIK40201.1 - 0.0037 16.9 0.0 2.7 7.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIK40201.1 - 0.0071 16.5 0.8 0.62 10.2 0.0 3.5 3 1 0 3 3 2 1 AAA domain AAA_28 PF13521.6 KIK40201.1 - 0.0093 16.2 0.5 0.12 12.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KIK40201.1 - 0.0095 15.5 0.4 1.1 8.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 KIK40201.1 - 0.011 14.9 0.0 4.6 6.3 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain FeoB_N PF02421.18 KIK40201.1 - 0.016 14.8 2.1 0.31 10.6 0.2 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B TsaE PF02367.17 KIK40201.1 - 0.034 14.1 0.0 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 KIK40201.1 - 0.05 13.2 0.4 5.7 6.5 0.2 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain G-alpha PF00503.20 KIK40201.1 - 0.052 12.7 0.0 0.32 10.1 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 KIK40201.1 - 0.057 13.2 0.1 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KIK40201.1 - 0.1 12.2 0.2 2.9 7.4 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Opi1 PF08618.10 KIK40203.1 - 3.8e-123 411.9 16.2 5.9e-90 302.5 13.8 2.2 1 1 1 2 2 2 2 Transcription factor Opi1 Perilipin PF03036.16 KIK40203.1 - 1.6e-05 24.1 0.1 4.8e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Perilipin family REF PF05755.12 KIK40203.1 - 0.045 13.6 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) zf-C2H2 PF00096.26 KIK40204.1 - 1.7e-13 50.2 9.6 7.7e-06 26.1 6.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK40204.1 - 6.5e-07 29.7 9.2 0.0019 18.8 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK40204.1 - 8.5e-07 29.1 12.4 2e-05 24.8 0.2 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 KIK40204.1 - 0.003 17.3 8.6 0.12 12.1 0.9 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 KIK40204.1 - 0.08 13.1 3.1 0.24 11.5 2.8 1.7 1 1 1 2 2 2 0 Aberrant zinc-finger zf-RAG1 PF10426.9 KIK40204.1 - 0.23 11.7 0.0 0.23 11.7 0.0 2.1 2 1 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain FOXP-CC PF16159.5 KIK40204.1 - 0.89 10.2 3.4 6.6 7.4 1.7 2.1 1 1 1 2 2 2 0 FOXP coiled-coil domain DUF629 PF04780.12 KIK40204.1 - 3.6 6.0 5.2 7.2 5.0 2.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Pkinase_Tyr PF07714.17 KIK40206.1 - 4.1e-19 68.9 0.0 5.2e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK40206.1 - 6.3e-18 65.1 0.0 7.4e-18 64.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIK40206.1 - 0.15 11.7 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 KIK40207.1 - 3.3e-40 138.0 0.0 4.4e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK40207.1 - 1.6e-31 109.6 0.0 2.3e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK40207.1 - 0.0058 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIK40207.1 - 0.077 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KIK40207.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KIK40209.1 - 0.0016 17.3 0.1 0.0026 16.6 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase HET PF06985.11 KIK40211.1 - 0.0027 18.1 0.1 0.0094 16.3 0.0 1.7 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Ribosomal_L37e PF01907.19 KIK40212.1 - 1.3e-25 89.3 14.4 2.1e-25 88.6 14.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e Ras PF00071.22 KIK40213.1 - 3.4e-37 127.5 0.0 1.7e-35 122.0 0.0 2.2 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KIK40213.1 - 3.9e-28 98.1 0.0 6.3e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK40213.1 - 9e-07 28.5 0.0 2e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIK40213.1 - 0.00078 19.0 0.0 0.0037 16.8 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KIK40213.1 - 0.00093 18.6 0.0 0.0018 17.6 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIK40213.1 - 0.002 18.2 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PolyA_pol_arg_C PF12626.7 KIK40213.1 - 0.081 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus CytochromB561_N PF09786.9 KIK40213.1 - 5.6 5.8 9.5 7.5 5.4 9.5 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal LSM PF01423.22 KIK40214.1 - 8.5e-18 63.8 0.3 9.7e-18 63.6 0.3 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIK40214.1 - 4.5e-05 23.5 0.2 5.4e-05 23.3 0.2 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Hfq PF17209.3 KIK40214.1 - 0.16 11.7 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 Hfq protein O-FucT PF10250.9 KIK40215.1 - 0.0088 15.8 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Gemini_mov PF01708.16 KIK40216.1 - 0.015 15.0 0.2 0.021 14.6 0.2 1.5 1 1 0 1 1 1 0 Geminivirus putative movement protein Pro_CA PF00484.19 KIK40219.1 - 1.1e-38 133.0 0.0 1.3e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Abhydrolase_6 PF12697.7 KIK40219.1 - 0.2 12.3 4.2 0.56 10.8 2.8 2.2 1 1 2 3 3 3 0 Alpha/beta hydrolase family Gtr1_RagA PF04670.12 KIK40220.1 - 1.9e-45 155.0 0.1 2.6e-45 154.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KIK40220.1 - 1.6e-05 24.4 0.0 2.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KIK40220.1 - 0.00077 18.9 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KIK40220.1 - 0.0034 17.4 0.0 0.0062 16.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KIK40220.1 - 0.0094 16.2 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 KIK40220.1 - 0.027 14.5 0.2 0.078 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Ras PF00071.22 KIK40220.1 - 0.17 11.5 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Ras family G-alpha PF00503.20 KIK40220.1 - 0.18 10.9 0.6 0.42 9.7 0.6 1.8 1 1 0 1 1 1 0 G-protein alpha subunit DUF3085 PF11284.8 KIK40220.1 - 0.2 12.0 0.0 0.33 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) MerC PF03203.14 KIK40222.1 - 1.1 9.7 14.9 0.21 12.1 10.1 2.3 2 2 0 2 2 2 0 MerC mercury resistance protein WD40 PF00400.32 KIK40223.1 - 2.1e-05 25.2 1.2 0.019 15.8 0.1 3.0 2 1 0 2 2 2 2 WD domain, G-beta repeat Pkinase_fungal PF17667.1 KIK40225.1 - 8.5e-22 77.5 0.0 3.4e-21 75.5 0.0 1.8 1 1 1 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 KIK40225.1 - 0.0014 18.1 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF3581 PF12119.8 KIK40226.1 - 0.13 11.6 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3581) HET PF06985.11 KIK40227.1 - 4e-05 24.0 0.6 0.00015 22.1 0.2 1.9 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Malic_M PF03949.15 KIK40228.1 - 5.8e-60 202.7 0.0 7.7e-45 153.2 0.0 2.1 1 1 1 2 2 2 2 Malic enzyme, NAD binding domain malic PF00390.19 KIK40228.1 - 1.8e-18 66.9 0.0 2.9e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Shikimate_DH PF01488.20 KIK40228.1 - 0.045 13.8 0.0 0.067 13.3 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4057 PF13266.6 KIK40228.1 - 0.26 10.9 0.0 0.39 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4057) NmrA PF05368.13 KIK40229.1 - 2.1e-11 43.8 0.0 3.5e-11 43.1 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family UDG PF03167.19 KIK40231.1 - 9.5e-15 54.9 0.0 3.3e-14 53.2 0.0 1.9 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily Piwi PF02171.17 KIK40232.1 - 3.1e-73 246.7 0.0 1.7e-71 240.9 0.0 2.2 1 1 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KIK40232.1 - 1.6e-25 90.3 0.0 2.8e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KIK40232.1 - 3.4e-17 61.8 0.1 8.4e-17 60.6 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 KIK40232.1 - 1.2e-14 54.3 0.2 2.9e-14 53.1 0.2 1.6 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 KIK40232.1 - 1.7e-13 50.7 0.0 3.9e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 KIK40232.1 - 8e-09 35.4 0.0 1.6e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 PAZ domain HET PF06985.11 KIK40234.1 - 2.6e-11 44.1 0.5 9.8e-08 32.5 0.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ANAPC4_WD40 PF12894.7 KIK40236.1 - 0.016 15.5 0.0 6.2 7.2 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK40236.1 - 0.023 15.6 0.1 0.47 11.4 0.0 2.8 3 0 0 3 3 3 0 WD domain, G-beta repeat SET PF00856.28 KIK40237.1 - 4.9e-09 36.8 0.1 3.3e-08 34.1 0.1 2.1 1 1 0 1 1 1 1 SET domain p450 PF00067.22 KIK40238.1 - 9.6e-63 212.5 0.0 1.1e-62 212.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GH3 PF03321.13 KIK40239.1 - 4.5e-74 250.2 0.0 5.4e-74 249.9 0.0 1.0 1 0 0 1 1 1 1 GH3 auxin-responsive promoter Transp_cyt_pur PF02133.15 KIK40241.1 - 0.017 13.9 0.1 0.024 13.4 0.1 1.2 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin NUC153 PF08159.12 KIK40246.1 - 7e-12 44.9 0.3 1.3e-11 44.1 0.3 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KIK40246.1 - 0.012 16.4 1.8 21 6.2 0.2 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40246.1 - 0.14 12.5 0.0 4.6 7.6 0.0 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Cwf_Cwc_15 PF04889.12 KIK40246.1 - 0.42 10.3 17.9 1 9.0 8.1 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SURF4 PF02077.15 KIK40247.1 - 6.2e-92 308.0 9.8 7.2e-92 307.8 9.8 1.0 1 0 0 1 1 1 1 SURF4 family Halogen_Hydrol PF10112.9 KIK40247.1 - 0.63 10.0 6.7 0.35 10.8 0.4 2.4 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF3395 PF11875.8 KIK40248.1 - 2.4e-31 108.7 0.3 6.7e-31 107.3 0.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 KIK40248.1 - 8.5e-18 64.2 0.0 1.5e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Gti1_Pac2 PF09729.9 KIK40250.1 - 1.4e-27 97.0 1.1 4.3e-25 88.9 0.0 2.5 2 1 1 3 3 3 2 Gti1/Pac2 family Glyco_hydro_59M PF17387.2 KIK40250.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 central domain Dimer_Tnp_hAT PF05699.14 KIK40253.1 - 8.1e-06 25.5 0.0 2.7e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KIK40253.1 - 0.00038 20.8 1.1 0.014 15.7 0.2 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4413) Asp-B-Hydro_N PF05279.11 KIK40254.1 - 0.28 11.2 6.5 0.4 10.7 6.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DDE_Tnp_4 PF13359.6 KIK40255.1 - 5.1e-27 94.5 0.0 1e-25 90.3 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 KIK40255.1 - 1.9e-05 24.4 0.0 2.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 KIK40255.1 - 5.5e-05 22.9 1.1 0.0025 17.5 0.4 2.8 2 1 0 2 2 2 1 Transposase DDE domain tRNA-synt_1 PF00133.22 KIK40257.1 - 5.8e-150 500.4 0.0 6.9e-150 500.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KIK40257.1 - 3.1e-22 79.2 0.3 6.9e-22 78.1 0.3 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KIK40257.1 - 9.8e-20 70.6 0.2 8.9e-14 51.0 0.1 3.5 3 0 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.14 KIK40257.1 - 9.2e-06 25.4 4.7 1.8e-05 24.4 4.7 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.19 KIK40257.1 - 0.0019 17.6 0.0 2.1 7.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain RecR PF02132.15 KIK40257.1 - 0.15 11.6 1.0 0.37 10.4 1.0 1.6 1 0 0 1 1 1 0 RecR protein zf-UDP PF14569.6 KIK40257.1 - 0.18 11.9 0.3 0.38 10.9 0.3 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger DJ-1_PfpI PF01965.24 KIK40258.1 - 6e-30 104.2 0.0 7.4e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KIK40258.1 - 0.0011 18.7 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 ThiJ/PfpI family-like ProRS-C_1 PF09180.11 KIK40259.1 - 2.3e-25 88.6 0.9 4.7e-25 87.6 0.9 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KIK40259.1 - 2.6e-17 63.4 0.0 6.4e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KIK40259.1 - 4.2e-16 58.9 0.0 1.8e-15 56.9 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain tRNA_edit PF04073.15 KIK40259.1 - 1.4e-13 51.0 0.0 2.6e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Sugar_tr PF00083.24 KIK40260.1 - 1.1e-110 370.6 21.9 1.3e-110 370.4 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK40260.1 - 7.4e-20 71.2 35.4 4.5e-16 58.7 10.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KIK40260.1 - 0.25 11.9 2.5 0.2 12.2 0.3 2.0 2 0 0 2 2 2 0 Phage holin family 2 OTT_1508_deam PF14441.6 KIK40263.1 - 0.029 14.4 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 OTT_1508-like deaminase MMR_HSR1 PF01926.23 KIK40265.1 - 3.5e-23 81.9 0.0 3.3e-11 43.3 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase AIG1 PF04548.16 KIK40265.1 - 4.9e-13 48.9 0.0 1e-06 28.2 0.0 2.2 2 0 0 2 2 2 2 AIG1 family Dynamin_N PF00350.23 KIK40265.1 - 6e-11 42.7 0.2 0.0014 18.7 0.0 3.5 2 1 0 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 KIK40265.1 - 1.5e-10 41.2 0.0 0.00036 20.5 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase ABC_tran PF00005.27 KIK40265.1 - 1.6e-10 41.6 0.1 0.0009 19.8 0.0 2.9 2 1 0 2 2 2 2 ABC transporter Roc PF08477.13 KIK40265.1 - 2.1e-10 40.8 1.4 0.00026 21.2 0.0 3.8 4 0 0 4 4 4 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KIK40265.1 - 6.6e-09 35.6 0.2 3.9e-05 23.3 0.0 3.0 2 1 0 2 2 2 2 Ras family AAA_16 PF13191.6 KIK40265.1 - 5.5e-07 30.1 0.2 0.014 15.8 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KIK40265.1 - 3.1e-06 27.5 0.4 0.09 13.1 0.1 3.6 3 1 0 3 3 3 2 AAA domain DUF815 PF05673.13 KIK40265.1 - 2.3e-05 23.7 0.1 0.27 10.3 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_24 PF13479.6 KIK40265.1 - 0.00016 21.5 0.5 1.1 9.0 0.1 3.2 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 KIK40265.1 - 0.00022 21.4 0.3 0.066 13.3 0.0 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain RNA_helicase PF00910.22 KIK40265.1 - 0.00029 21.2 0.0 0.9 10.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_23 PF13476.6 KIK40265.1 - 0.00041 20.9 3.6 0.07 13.6 0.8 3.1 3 1 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 KIK40265.1 - 0.00043 19.6 0.1 0.24 10.6 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 KIK40265.1 - 0.00051 19.7 0.1 0.52 10.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_13 PF13166.6 KIK40265.1 - 0.00052 18.8 0.0 0.42 9.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain DLIC PF05783.11 KIK40265.1 - 0.00065 18.7 0.1 0.042 12.7 0.0 2.4 3 0 0 3 3 2 1 Dynein light intermediate chain (DLIC) Sigma54_activat PF00158.26 KIK40265.1 - 0.0013 18.5 0.0 0.57 9.9 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain PduV-EutP PF10662.9 KIK40265.1 - 0.0036 17.1 0.0 0.2 11.4 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 KIK40265.1 - 0.0044 17.0 0.0 4 7.5 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KIK40265.1 - 0.0058 16.6 0.1 1.7 8.5 0.0 2.9 3 0 0 3 3 2 1 NACHT domain FeoB_N PF02421.18 KIK40265.1 - 0.013 15.1 0.0 0.77 9.3 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 KIK40265.1 - 0.02 14.4 0.1 6.3 6.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 KIK40265.1 - 0.02 15.1 0.3 4.4 7.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain Septin PF00735.18 KIK40265.1 - 0.021 14.1 0.0 0.76 9.0 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_18 PF13238.6 KIK40265.1 - 0.026 15.1 0.2 6.5 7.3 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 KIK40265.1 - 0.026 15.0 0.1 14 6.1 0.0 2.9 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIK40265.1 - 0.026 14.5 0.0 5.3 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IIGP PF05049.13 KIK40265.1 - 0.035 13.1 0.1 3.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) DUF104 PF01954.16 KIK40265.1 - 0.039 14.4 1.9 0.15 12.5 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF104 AAA_10 PF12846.7 KIK40265.1 - 0.041 12.8 0.1 2.1 7.2 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain Gtr1_RagA PF04670.12 KIK40265.1 - 0.048 13.0 0.0 9 5.6 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region SMC_N PF02463.19 KIK40265.1 - 0.067 12.6 0.2 9.3 5.6 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 KIK40265.1 - 0.084 12.5 0.1 15 5.2 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 KIK40265.1 - 0.11 12.0 0.1 3.5 7.1 0.0 2.7 3 0 0 3 3 3 0 ADP-ribosylation factor family Apelin PF15360.6 KIK40265.1 - 0.12 12.9 0.0 0.32 11.6 0.0 1.7 1 0 0 1 1 1 0 APJ endogenous ligand KAP_NTPase PF07693.14 KIK40265.1 - 0.15 11.3 0.0 4.5 6.4 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain AAA_30 PF13604.6 KIK40265.1 - 0.16 11.7 0.2 13 5.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 KIK40266.1 - 1.6e-67 227.7 0.0 2e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK40266.1 - 2.5e-28 99.1 0.0 3.3e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK40266.1 - 0.00022 20.3 0.0 0.00034 19.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Phenol_Hydrox PF02332.18 KIK40266.1 - 0.37 10.3 1.1 0.62 9.6 1.1 1.3 1 0 0 1 1 1 0 Methane/Phenol/Toluene Hydroxylase DAO PF01266.24 KIK40267.1 - 3.4e-32 112.4 0.2 3.9e-32 112.2 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK40267.1 - 6.3e-05 22.2 0.0 9e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK40267.1 - 0.0084 15.4 0.0 0.04 13.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KIK40267.1 - 0.044 14.2 0.0 0.073 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KIK40267.1 - 0.053 13.8 0.1 0.15 12.3 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Glu_dehyd_C PF16912.5 KIK40267.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Pyr_redox_3 PF13738.6 KIK40267.1 - 0.1 11.9 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK40267.1 - 0.15 12.6 0.6 0.28 11.8 0.6 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK40267.1 - 0.16 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Sacchrp_dh_NADP PF03435.18 KIK40267.1 - 0.16 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain P53_TAD PF08563.11 KIK40267.1 - 0.31 10.6 0.9 0.61 9.6 0.9 1.4 1 0 0 1 1 1 0 P53 transactivation motif MFS_1 PF07690.16 KIK40268.1 - 8.8e-45 153.1 25.9 1.4e-44 152.5 25.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK40268.1 - 2e-16 59.9 25.1 5.6e-13 48.6 5.8 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 KIK40268.1 - 4.2e-06 25.3 2.6 4.2e-06 25.3 2.6 2.0 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family FA_desaturase PF00487.24 KIK40269.1 - 8.6e-23 81.5 16.6 8.6e-23 81.5 16.6 1.6 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 KIK40269.1 - 5.5e-18 64.2 0.3 1e-17 63.3 0.3 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) DUF4442 PF14539.6 KIK40269.1 - 0.092 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) WD40 PF00400.32 KIK40270.1 - 8.8e-34 115.0 11.4 7.9e-09 36.0 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40270.1 - 8.7e-12 45.2 0.0 0.042 14.1 0.0 4.4 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK40270.1 - 2.2e-07 30.7 6.3 0.74 9.8 0.0 5.3 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK40270.1 - 4.6e-07 29.1 0.0 0.34 9.8 0.0 4.1 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 KIK40270.1 - 0.00016 21.5 0.9 0.016 15.0 0.2 2.6 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 KIK40270.1 - 0.0059 15.3 0.2 0.93 8.1 0.0 3.1 1 1 2 4 4 4 1 Nucleoporin Nup120/160 DUF5570 PF17731.1 KIK40270.1 - 0.016 15.3 2.6 2.3 8.3 0.1 3.6 1 1 3 4 4 4 0 Family of unknown function (DUF5570) WD40_3 PF15911.5 KIK40270.1 - 0.054 13.5 0.1 68 3.6 0.0 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat WD40_like PF17005.5 KIK40270.1 - 0.067 12.5 0.0 10 5.4 0.0 2.4 1 1 1 2 2 2 0 WD40-like domain DUF4875 PF16175.5 KIK40270.1 - 0.067 13.3 0.2 0.45 10.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4875) Peptidase_S9_N PF02897.15 KIK40270.1 - 0.19 10.5 0.0 2.9 6.6 0.0 2.2 1 1 1 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain GCM PF03615.15 KIK40271.1 - 1.3 8.9 13.6 0.26 11.2 7.3 3.0 2 1 0 2 2 2 0 GCM motif protein LRR_4 PF12799.7 KIK40273.1 - 1.7e-05 25.0 2.1 0.019 15.4 0.5 3.8 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KIK40273.1 - 0.0018 18.5 2.5 8.3 7.4 0.0 4.1 3 1 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 KIK40273.1 - 0.0054 16.7 9.6 12 6.3 0.0 5.1 6 0 0 6 6 6 2 Leucine Rich repeat LRR_8 PF13855.6 KIK40273.1 - 0.14 12.0 5.4 5.2 6.9 0.2 3.4 3 0 0 3 3 3 0 Leucine rich repeat HSP70 PF00012.20 KIK40283.1 - 6.2e-11 41.2 0.0 6.8e-11 41.1 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Pox_D5 PF03288.16 KIK40283.1 - 0.08 13.4 0.0 0.08 13.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus D5 protein-like RVT_1 PF00078.27 KIK40284.1 - 0.043 13.3 0.2 0.061 12.8 0.2 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) KDZ PF18758.1 KIK40285.1 - 1e-60 205.2 2.1 1.9e-60 204.2 2.1 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC3 PF18804.1 KIK40285.1 - 0.0089 15.9 0.1 0.023 14.5 0.1 1.7 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases HupE_UreJ PF04955.12 KIK40285.1 - 0.049 13.1 0.2 0.093 12.2 0.2 1.4 1 0 0 1 1 1 0 HupE / UreJ protein CxC1 PF18802.1 KIK40285.1 - 0.052 13.7 0.1 0.24 11.6 0.1 2.2 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases Myb_CC_LHEQLE PF14379.6 KIK40289.1 - 0.13 12.0 0.6 0.13 12.0 0.6 1.8 2 0 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif Med23 PF11573.8 KIK40291.1 - 0.061 11.0 0.0 0.08 10.6 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 23 Lyase_1 PF00206.20 KIK40297.1 - 1.6e-39 136.2 0.0 2.3e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KIK40297.1 - 1e-20 74.0 0.0 2.5e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Crp PF00325.20 KIK40297.1 - 0.056 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family ABC2_membrane PF01061.24 KIK40298.1 - 4.8e-79 264.6 53.0 3.7e-41 140.9 22.0 3.2 5 0 0 5 5 4 2 ABC-2 type transporter ABC_tran PF00005.27 KIK40298.1 - 3.3e-35 121.6 0.0 5.8e-17 62.5 0.0 3.0 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KIK40298.1 - 1e-32 111.9 10.1 3.8e-29 100.4 0.2 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KIK40298.1 - 1.2e-14 54.6 0.3 3.1e-14 53.4 0.3 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KIK40298.1 - 2.7e-06 27.9 0.0 0.0055 17.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIK40298.1 - 2.7e-06 27.4 0.1 3.8e-05 23.7 0.0 2.5 3 0 0 3 3 3 1 RsgA GTPase ABC2_membrane_3 PF12698.7 KIK40298.1 - 3.4e-06 26.4 15.3 3.4e-06 26.4 15.3 3.6 2 1 0 3 3 3 1 ABC-2 family transporter protein AAA_22 PF13401.6 KIK40298.1 - 1.3e-05 25.5 0.1 0.061 13.6 0.1 3.2 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KIK40298.1 - 1.9e-05 24.3 2.0 0.27 11.0 0.2 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain NACHT PF05729.12 KIK40298.1 - 9e-05 22.4 0.1 0.19 11.6 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_25 PF13481.6 KIK40298.1 - 9.1e-05 22.1 0.0 0.011 15.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KIK40298.1 - 0.00026 20.9 0.0 0.081 12.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KIK40298.1 - 0.0014 18.6 0.0 0.77 9.9 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC2_membrane_2 PF12679.7 KIK40298.1 - 0.0043 16.4 8.8 0.0043 16.4 8.8 2.3 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_18 PF13238.6 KIK40298.1 - 0.01 16.4 0.0 1.3 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KIK40298.1 - 0.013 14.9 0.0 0.19 11.1 0.0 2.5 3 0 0 3 3 2 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KIK40298.1 - 0.019 14.7 0.0 0.85 9.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KIK40298.1 - 0.021 14.5 0.1 5.7 6.7 0.1 2.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KIK40298.1 - 0.024 14.2 0.2 0.65 9.6 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KIK40298.1 - 0.025 14.8 0.0 0.96 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KIK40298.1 - 0.029 14.7 0.0 6.9 7.1 0.0 2.8 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 KIK40298.1 - 0.061 13.3 0.2 0.3 11.1 0.1 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KIK40298.1 - 0.063 13.7 0.0 4.5 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KIK40298.1 - 0.085 13.1 0.0 7.6 6.9 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit dNK PF01712.19 KIK40298.1 - 0.12 12.2 0.0 0.46 10.3 0.0 1.9 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA PF00004.29 KIK40298.1 - 0.13 12.7 0.0 7.6 7.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KIK40298.1 - 0.16 12.3 0.1 17 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KIK40298.1 - 0.17 12.4 0.1 0.31 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KIK40298.1 - 0.19 11.0 0.1 4.2 6.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Septin PF00735.18 KIK40298.1 - 0.22 10.8 0.0 5.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Septin ANAPC4_WD40 PF12894.7 KIK40300.1 - 1.8e-16 60.2 4.9 8.5e-06 26.0 0.0 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK40300.1 - 1.3e-14 54.3 16.8 1e-05 26.1 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.11 KIK40300.1 - 0.0036 17.2 0.0 0.24 11.3 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A AP3B1_C PF14796.6 KIK40300.1 - 0.068 13.4 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Ge1_WD40 PF16529.5 KIK40300.1 - 0.087 11.8 0.0 3.8 6.4 0.0 3.0 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ABC2_membrane PF01061.24 KIK40301.1 - 5.3e-78 261.2 50.5 1.5e-41 142.1 21.7 3.5 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KIK40301.1 - 1e-36 126.5 0.0 2.7e-17 63.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KIK40301.1 - 8.2e-31 105.8 5.4 1.7e-27 95.1 0.1 3.6 3 1 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KIK40301.1 - 5.6e-12 46.1 0.0 1.4e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KIK40301.1 - 1.6e-06 28.6 0.0 0.003 18.0 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIK40301.1 - 2e-06 27.8 0.1 3.3e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KIK40301.1 - 1e-05 25.8 0.0 0.071 13.4 0.1 3.3 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KIK40301.1 - 0.00012 21.7 0.1 0.031 13.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KIK40301.1 - 0.00021 21.2 0.0 0.073 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KIK40301.1 - 0.00023 20.4 49.1 0.00034 19.8 22.5 3.1 2 1 0 2 2 2 1 ABC-2 family transporter protein NACHT PF05729.12 KIK40301.1 - 0.00037 20.5 0.0 0.11 12.4 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 KIK40301.1 - 0.00045 20.8 0.0 0.49 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIK40301.1 - 0.0005 20.2 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KIK40301.1 - 0.00089 18.9 0.7 0.22 11.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KIK40301.1 - 0.0031 17.6 0.0 0.8 9.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase dNK PF01712.19 KIK40301.1 - 0.0058 16.5 0.0 0.29 10.9 0.0 2.5 2 0 0 2 2 2 1 Deoxynucleoside kinase SMC_N PF02463.19 KIK40301.1 - 0.006 16.1 0.0 0.092 12.2 0.0 2.6 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 KIK40301.1 - 0.016 14.8 0.3 0.39 10.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KIK40301.1 - 0.027 14.9 0.0 13 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KIK40301.1 - 0.038 14.0 0.0 0.37 10.8 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KIK40301.1 - 0.061 13.7 0.0 7.9 6.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 KIK40301.1 - 0.081 12.6 0.0 4.4 7.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain Rad51 PF08423.11 KIK40301.1 - 0.084 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Rad51 Septin PF00735.18 KIK40301.1 - 0.093 12.0 0.0 5.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Septin SbcCD_C PF13558.6 KIK40301.1 - 0.11 12.7 0.1 7.4 6.9 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KIK40301.1 - 0.13 12.0 0.7 1.4 8.6 0.2 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KIK40301.1 - 0.13 12.5 0.0 2 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KIK40301.1 - 0.15 11.9 0.0 18 5.2 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_23 PF13476.6 KIK40301.1 - 0.18 12.3 0.1 0.34 11.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KIK40301.1 - 0.19 12.2 0.0 7.1 7.1 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cornifin PF02389.15 KIK40302.1 - 1.1e-05 25.6 2.5 1.1e-05 25.6 2.5 1.9 2 0 0 2 2 2 1 Cornifin (SPRR) family Sec10 PF07393.11 KIK40306.1 - 2e-121 406.7 0.0 2.8e-121 406.2 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.33 KIK40306.1 - 0.01 15.7 0.1 0.019 14.8 0.1 1.5 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KIK40306.1 - 0.056 13.4 0.0 1.3 9.0 0.1 2.6 2 0 0 2 2 2 0 F-box-like Whi5 PF08528.11 KIK40307.1 - 3e-08 33.1 1.1 4.8e-08 32.4 1.1 1.4 1 0 0 1 1 1 1 Whi5 like POPLD PF08170.12 KIK40307.1 - 0.11 12.9 0.4 0.13 12.7 0.4 1.2 1 0 0 1 1 1 0 POPLD (NUC188) domain CTP_transf_1 PF01148.20 KIK40309.1 - 0.0062 16.3 1.7 0.011 15.5 1.6 1.6 1 1 0 1 1 1 1 Cytidylyltransferase family Ribosomal_S8 PF00410.19 KIK40310.1 - 2.3e-24 85.8 0.1 3e-24 85.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S17e PF00833.18 KIK40311.1 - 2.2e-59 198.7 0.6 2.5e-59 198.5 0.3 1.3 1 1 0 1 1 1 1 Ribosomal S17 MFS_1 PF07690.16 KIK40315.1 - 8.7e-25 87.4 47.7 4.5e-21 75.1 49.0 3.6 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIK40315.1 - 2.4e-07 29.6 11.3 2.4e-07 29.6 11.3 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3169 PF11368.8 KIK40315.1 - 1.2 8.6 8.1 0.041 13.4 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3169) Nup96 PF12110.8 KIK40319.1 - 0.15 11.2 0.0 0.15 11.2 0.0 1.0 1 0 0 1 1 1 0 Nuclear protein 96 ATP-synt_J PF04911.12 KIK40321.1 - 2.8e-22 78.0 0.3 3.1e-22 77.9 0.3 1.0 1 0 0 1 1 1 1 ATP synthase j chain Adaptin_N PF01602.20 KIK40322.1 - 1.4e-95 320.8 6.4 2.5e-95 320.1 6.4 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 KIK40322.1 - 5e-60 201.1 0.0 1.5e-59 199.5 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 KIK40322.1 - 2.8e-53 179.6 0.0 7.3e-53 178.3 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 KIK40322.1 - 2.5e-10 40.6 0.1 0.024 15.0 0.0 5.4 2 1 3 5 5 5 2 HEAT repeats HEAT PF02985.22 KIK40322.1 - 9.5e-08 31.7 1.0 0.16 12.3 0.0 5.9 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 KIK40322.1 - 1.3e-05 25.3 12.7 0.0058 16.7 0.0 4.7 2 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 DUF5578 PF17741.1 KIK40322.1 - 0.00047 19.7 6.9 0.34 10.3 2.1 3.6 1 1 1 3 3 3 3 Family of unknown function (DUF5578) DUF5071 PF16804.5 KIK40322.1 - 0.0019 18.4 1.1 0.095 13.0 0.0 3.6 1 1 3 4 4 4 1 Domain of unknown function (DUF5071) Gemini_V2 PF01524.17 KIK40322.1 - 0.0051 17.0 0.0 0.064 13.4 0.0 2.6 2 0 0 2 2 2 1 Geminivirus V2 protein RTP1_C1 PF10363.9 KIK40322.1 - 0.0069 16.6 6.4 0.25 11.5 0.1 3.9 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 KIK40322.1 - 0.023 15.1 5.3 16 5.9 0.1 4.8 5 1 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_EZ PF13513.6 KIK40322.1 - 0.024 15.1 0.0 15 6.2 0.0 4.6 6 0 0 6 6 5 0 HEAT-like repeat ParcG PF10274.9 KIK40322.1 - 0.053 13.6 1.7 1.2 9.2 0.0 2.8 2 1 0 2 2 2 0 Parkin co-regulated protein Meis_PKNOX_N PF16493.5 KIK40322.1 - 0.06 13.7 2.3 0.12 12.8 0.5 2.4 2 0 0 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 PDZ_1 PF12812.7 KIK40323.1 - 0.18 11.8 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 PDZ-like domain Plavaka PF18759.1 KIK40327.1 - 1.9e-40 139.1 0.0 2.5e-40 138.7 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase Pkinase PF00069.25 KIK40336.1 - 8.2e-08 31.9 0.7 8.2e-08 31.9 0.7 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK40336.1 - 1.4e-05 24.5 0.4 1.4e-05 24.5 0.4 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIK40336.1 - 0.0026 17.2 1.2 0.0026 17.2 1.2 1.0 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HetR_C PF18460.1 KIK40336.1 - 0.015 15.2 0.0 0.016 15.2 0.0 1.0 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain Pkinase_fungal PF17667.1 KIK40336.1 - 1.5 7.5 4.5 0.58 8.9 2.1 1.5 1 1 1 2 2 2 0 Fungal protein kinase p450 PF00067.22 KIK40337.1 - 7.1e-66 222.8 0.0 9.7e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SDP_N PF12278.8 KIK40338.1 - 0.0073 16.4 0.3 0.012 15.7 0.3 1.5 1 1 0 1 1 1 1 Sex determination protein N terminal PHD PF00628.29 KIK40338.1 - 0.12 12.3 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 PHD-finger HTH_33 PF13592.6 KIK40339.1 - 0.0046 16.6 0.1 2.5 7.8 0.0 2.4 2 0 0 2 2 2 2 Winged helix-turn helix HTH_21 PF13276.6 KIK40339.1 - 0.0095 16.1 0.2 0.04 14.1 0.1 1.9 2 0 0 2 2 2 1 HTH-like domain HTH_32 PF13565.6 KIK40339.1 - 0.015 15.9 0.4 2.4 8.8 0.0 2.3 1 1 1 2 2 2 0 Homeodomain-like domain DASH_Dam1 PF08653.10 KIK40340.1 - 2.2e-23 81.8 0.1 3.6e-23 81.1 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Dam1 NAPRTase_N PF17767.1 KIK40340.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Sec23_trunk PF04811.15 KIK40341.1 - 9.1e-74 248.1 0.0 1.3e-73 247.6 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KIK40341.1 - 2.1e-17 63.6 0.8 7e-14 52.3 0.1 2.7 1 1 1 2 2 2 2 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KIK40341.1 - 1.1e-15 57.3 7.2 2e-15 56.5 7.2 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KIK40341.1 - 1.3e-14 53.8 0.1 2.6e-13 49.7 0.0 2.7 3 0 0 3 3 3 1 Gelsolin repeat Sec23_helical PF04815.15 KIK40341.1 - 3.4e-14 52.5 0.7 2e-13 50.0 0.7 2.0 1 1 0 1 1 1 1 Sec23/Sec24 helical domain Vps36-NZF-N PF16988.5 KIK40341.1 - 0.12 11.8 0.1 0.29 10.6 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain E1-E2_ATPase PF00122.20 KIK40342.1 - 2.9e-22 79.0 0.1 6.6e-22 77.9 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KIK40342.1 - 3.6e-13 50.3 0.0 6.1e-07 29.9 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIK40342.1 - 0.0013 18.8 0.0 0.0031 17.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KIK40342.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KIK40342.1 - 0.07 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Glucos_trans_II PF14264.6 KIK40342.1 - 0.086 12.2 0.1 0.086 12.2 0.1 2.9 3 0 0 3 3 3 0 Glucosyl transferase GtrII CHAT PF12770.7 KIK40343.1 - 1.8e-32 112.9 0.1 4.2e-32 111.7 0.0 1.6 2 0 0 2 2 2 1 CHAT domain TPR_10 PF13374.6 KIK40343.1 - 3.8e-13 48.8 10.6 1.9e-05 24.4 0.1 6.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK40343.1 - 2e-06 27.4 0.8 9.2 6.5 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIK40343.1 - 6e-05 23.3 17.6 0.32 11.3 0.2 6.4 5 2 1 6 6 6 4 Tetratricopeptide repeat MIT PF04212.18 KIK40343.1 - 0.00018 21.5 0.2 9.1 6.4 0.0 4.7 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 KIK40343.1 - 0.0013 19.2 0.9 2.8 8.5 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK40343.1 - 0.0018 18.2 10.9 7.3 7.0 0.0 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat PilJ PF13675.6 KIK40343.1 - 0.005 16.9 3.5 1 9.4 0.2 4.2 3 1 2 5 5 5 1 Type IV pili methyl-accepting chemotaxis transducer N-term TPR_1 PF00515.28 KIK40343.1 - 0.01 15.6 8.8 12 5.9 0.1 6.2 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK40343.1 - 0.047 13.4 2.2 20 4.9 0.0 4.4 5 0 0 5 5 5 0 TPR repeat TPR_14 PF13428.6 KIK40343.1 - 0.065 14.1 17.3 5.3 8.1 0.1 8.4 8 1 2 10 10 9 0 Tetratricopeptide repeat Zeta_toxin PF06414.12 KIK40343.1 - 0.1 11.8 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Vta1_C PF18097.1 KIK40343.1 - 0.29 10.9 6.7 1.4 8.6 0.0 4.8 5 0 0 5 5 5 0 Vta1 C-terminal domain WD40 PF00400.32 KIK40344.1 - 7e-12 45.7 0.5 3.7e-06 27.5 0.0 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40344.1 - 0.00011 22.5 0.0 0.00013 22.2 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK40344.1 - 0.019 13.6 0.1 0.027 13.2 0.1 1.4 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK40344.1 - 0.12 11.3 0.1 0.58 9.1 0.1 1.8 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KIK40345.1 - 7.5e-07 29.8 0.0 1.4e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat Herpes_gI PF01688.17 KIK40345.1 - 0.21 11.5 0.0 0.25 11.2 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I zf-RING_UBOX PF13445.6 KIK40348.1 - 7.9e-05 22.6 7.0 7.9e-05 22.6 7.0 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIK40348.1 - 0.0004 20.2 11.9 0.019 14.8 5.1 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK40348.1 - 0.00087 19.6 7.0 0.00087 19.6 7.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK40348.1 - 0.0016 18.2 6.3 0.0016 18.2 6.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK40348.1 - 0.0035 17.2 5.7 0.0035 17.2 5.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK40348.1 - 0.0066 16.6 5.0 0.0066 16.6 5.0 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING USP8_interact PF08941.10 KIK40348.1 - 0.0081 16.0 0.7 5.8 6.7 1.3 2.3 2 0 0 2 2 2 2 USP8 interacting DUF3584 PF12128.8 KIK40348.1 - 0.0081 13.7 4.6 0.011 13.3 4.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) zf-RING_6 PF14835.6 KIK40348.1 - 0.0087 15.9 1.6 0.018 14.9 1.6 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein CIAPIN1 PF05093.13 KIK40348.1 - 0.0092 16.5 0.5 0.0092 16.5 0.5 2.2 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis zf-RING_10 PF16685.5 KIK40348.1 - 0.02 15.0 3.2 0.02 15.0 3.2 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 PRP9_N PF16958.5 KIK40348.1 - 0.049 13.7 2.9 0.12 12.4 2.9 1.6 1 0 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus GP41 PF00517.17 KIK40348.1 - 0.072 13.0 0.3 0.11 12.3 0.3 1.3 1 0 0 1 1 1 0 Retroviral envelope protein zf-RING_5 PF14634.6 KIK40348.1 - 0.12 12.4 14.9 0.051 13.5 6.0 2.3 2 0 0 2 2 2 0 zinc-RING finger domain Uso1_p115_C PF04871.13 KIK40348.1 - 0.13 12.6 7.4 0.22 11.9 7.4 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region zf-CpG_bind_C PF12269.8 KIK40348.1 - 0.14 11.9 5.1 0.19 11.5 4.1 1.6 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain Prok-RING_4 PF14447.6 KIK40348.1 - 0.32 10.9 12.3 1.4 8.8 5.8 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 SlyX PF04102.12 KIK40348.1 - 0.68 10.6 7.2 3 8.5 7.0 2.1 1 1 0 1 1 1 0 SlyX OmpH PF03938.14 KIK40348.1 - 9.4 6.6 10.8 17 5.8 10.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Zn_ribbon_17 PF17120.5 KIK40348.1 - 9.5 5.9 11.4 31 4.3 8.6 2.6 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type Peptidase_M19 PF01244.21 KIK40349.1 - 1.1e-102 343.5 0.0 1.3e-102 343.2 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) MFS_1 PF07690.16 KIK40350.1 - 1.5e-44 152.4 32.4 1.5e-44 152.4 32.4 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK40350.1 - 1.7e-15 56.5 10.5 2.5e-15 55.9 10.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Mitofilin PF09731.9 KIK40351.1 - 0.0024 16.8 15.6 0.003 16.5 15.6 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Apolipoprotein PF01442.18 KIK40351.1 - 0.037 13.9 24.2 0.33 10.8 24.2 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1643 PF07799.12 KIK40351.1 - 0.45 10.7 3.0 0.45 10.7 1.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1643) Exonuc_VII_L PF02601.15 KIK40351.1 - 0.56 9.7 10.1 0.75 9.3 10.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 KIK40351.1 - 1.3 9.1 4.5 7 6.7 3.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KIK40351.1 - 1.4 8.2 17.6 2.3 7.5 17.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YtxH PF12732.7 KIK40351.1 - 1.6 9.3 31.8 98 3.6 0.8 3.9 2 1 0 2 2 2 0 YtxH-like protein DUF883 PF05957.13 KIK40351.1 - 3.6 8.2 26.4 3.2 8.4 7.9 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) AAA_18 PF13238.6 KIK40352.1 - 5.5e-06 27.0 0.3 5.2e-05 23.8 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIK40352.1 - 0.0018 18.4 0.0 0.0068 16.6 0.0 1.8 2 1 1 3 3 3 1 AAA domain KTI12 PF08433.10 KIK40352.1 - 0.011 15.2 0.1 0.13 11.7 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 KIK40352.1 - 0.016 14.5 0.1 0.036 13.4 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 KIK40352.1 - 0.046 14.0 0.1 0.1 12.9 0.1 1.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KIK40352.1 - 0.089 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Usg PF06233.12 KIK40352.1 - 0.14 12.3 0.2 4.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Usg-like family FAD_binding_2 PF00890.24 KIK40353.1 - 2.7e-89 300.1 1.7 3.4e-89 299.8 1.7 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KIK40353.1 - 4.4e-22 78.0 0.0 1.3e-21 76.5 0.0 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KIK40353.1 - 2e-13 50.6 2.2 8.3e-13 48.6 2.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK40353.1 - 4.3e-11 42.6 1.1 2.4e-10 40.1 0.4 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK40353.1 - 8.7e-10 38.7 0.4 5.8e-09 36.1 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KIK40353.1 - 2.8e-09 36.8 3.7 6.6e-09 35.6 3.7 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIK40353.1 - 4.8e-08 32.6 0.4 7.7e-08 32.0 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KIK40353.1 - 3.5e-06 26.0 6.5 0.00012 21.0 0.4 2.7 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 KIK40353.1 - 3.6e-05 23.0 5.2 9.1e-05 21.7 0.9 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KIK40353.1 - 9.1e-05 21.8 0.2 0.14 11.4 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK40353.1 - 0.00021 21.8 1.0 0.07 13.7 0.2 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK40353.1 - 0.00035 19.9 3.0 0.021 14.1 0.9 2.5 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 KIK40353.1 - 0.00056 19.3 1.8 0.0026 17.1 0.7 2.4 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 KIK40353.1 - 0.00099 18.5 0.8 0.0019 17.6 0.8 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KIK40353.1 - 0.0038 17.2 1.9 0.13 12.2 1.9 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KIK40353.1 - 0.0063 15.6 0.2 0.041 12.9 0.3 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 KIK40353.1 - 0.041 14.3 0.0 0.077 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding zf-C2H2 PF00096.26 KIK40357.1 - 0.00014 22.2 5.3 0.059 13.9 0.4 2.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK40357.1 - 0.00086 19.6 1.3 0.00086 19.6 1.3 1.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK40357.1 - 0.0019 18.9 7.4 0.057 14.3 1.3 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger RSS_P20 PF11757.8 KIK40357.1 - 0.0054 17.1 0.0 0.0073 16.7 0.0 1.2 1 0 0 1 1 1 1 Suppressor of RNA silencing P21-like N-terminal domain zf-TRAF PF02176.18 KIK40357.1 - 0.009 16.7 2.3 0.01 16.5 1.4 1.6 1 1 0 1 1 1 1 TRAF-type zinc finger DUF4729 PF15866.5 KIK40357.1 - 0.024 14.0 0.4 0.032 13.6 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4729) zf-met PF12874.7 KIK40357.1 - 0.033 14.6 1.3 0.23 11.9 0.3 2.6 2 1 0 2 2 2 0 Zinc-finger of C2H2 type zf-MYST PF17772.1 KIK40357.1 - 0.047 13.3 1.2 0.072 12.7 1.2 1.4 1 0 0 1 1 1 0 MYST family zinc finger domain zf-BED PF02892.15 KIK40357.1 - 0.05 13.6 7.6 0.2 11.7 0.4 2.6 2 1 0 2 2 2 0 BED zinc finger zf-Di19 PF05605.12 KIK40357.1 - 0.061 13.6 0.5 0.41 11.0 0.4 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding ExsD PF16806.5 KIK40357.1 - 0.12 12.2 0.2 13 5.6 0.2 2.0 1 1 1 2 2 2 0 Antiactivator protein ExsD Gifsy-2 PF13856.6 KIK40357.1 - 0.13 12.6 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 ATP-binding sugar transporter from pro-phage Evr1_Alr PF04777.13 KIK40359.1 - 1.2e-26 93.1 0.8 1.5e-26 92.8 0.8 1.1 1 0 0 1 1 1 1 Erv1 / Alr family DUF4028 PF13220.6 KIK40359.1 - 0.31 10.9 2.0 0.31 10.9 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4028) AA_permease PF00324.21 KIK40360.1 - 1.5e-09 37.0 2.5 1.7e-09 36.8 2.5 1.0 1 0 0 1 1 1 1 Amino acid permease Na_Ala_symp PF01235.17 KIK40360.1 - 0.0042 16.5 0.7 0.0047 16.3 0.7 1.1 1 0 0 1 1 1 1 Sodium:alanine symporter family PrgI PF12666.7 KIK40360.1 - 0.0082 16.8 0.1 0.011 16.5 0.1 1.1 1 0 0 1 1 1 1 PrgI family protein RTA1 PF04479.13 KIK40362.1 - 1.5e-50 171.7 5.6 1.5e-50 171.7 5.6 1.8 2 0 0 2 2 2 1 RTA1 like protein Acetyltransf_1 PF00583.25 KIK40363.1 - 2.4e-08 34.2 0.0 6.4e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK40363.1 - 1.9e-06 27.8 0.1 7.8e-05 22.6 0.0 2.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK40363.1 - 7.9e-06 26.2 0.0 2.4e-05 24.7 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK40363.1 - 0.00032 20.6 0.1 0.026 14.5 0.1 2.3 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 KIK40363.1 - 0.0045 17.1 0.0 0.0097 16.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KIK40363.1 - 0.076 13.1 0.0 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KIK40363.1 - 0.18 11.8 0.0 0.66 10.0 0.0 1.9 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase RRM_1 PF00076.22 KIK40364.1 - 6e-24 83.6 0.0 6.8e-24 83.5 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIK40364.1 - 0.079 12.6 0.0 0.097 12.3 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIK40364.1 - 0.091 12.6 0.0 0.18 11.7 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif HMG_box PF00505.19 KIK40365.1 - 6.6e-15 55.3 0.2 8.6e-15 54.9 0.2 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK40365.1 - 2.6e-07 31.1 0.1 3.4e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 HMG-box domain SepZ PF06066.11 KIK40366.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 SepZ YCII PF03795.14 KIK40368.1 - 2.2e-09 37.6 0.0 2.7e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain zf-C2H2 PF00096.26 KIK40369.1 - 0.085 13.3 0.9 0.085 13.3 0.9 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type MGC-24 PF05283.11 KIK40369.1 - 0.12 12.8 2.3 0.17 12.3 2.3 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin zf-C2H2_4 PF13894.6 KIK40369.1 - 0.43 11.6 0.4 0.43 11.6 0.4 3.4 3 1 0 3 3 3 0 C2H2-type zinc finger FixP_N PF14715.6 KIK40372.1 - 0.14 11.9 0.1 0.14 11.9 0.1 2.9 4 0 0 4 4 4 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Cytochrom_B561 PF03188.16 KIK40372.1 - 0.9 9.7 6.3 0.14 12.2 2.2 1.7 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 Trypan_PARP PF05887.11 KIK40374.1 - 0.004 17.1 9.2 0.012 15.5 9.2 1.8 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Zip PF02535.22 KIK40374.1 - 1.8 7.7 3.5 3.8 6.6 3.5 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4407 PF14362.6 KIK40374.1 - 5.9 6.1 8.1 9.5 5.5 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAD_binding_3 PF01494.19 KIK40375.1 - 2.3e-68 231.0 0.0 3.2e-68 230.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK40375.1 - 3.1e-06 26.6 0.0 0.00025 20.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK40375.1 - 6.2e-05 22.2 0.0 0.00019 20.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KIK40375.1 - 7.9e-05 21.5 0.0 0.00054 18.8 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KIK40375.1 - 0.00014 21.5 0.0 0.00083 19.0 0.0 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK40375.1 - 0.00014 22.0 0.0 0.00035 20.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIK40375.1 - 0.00028 20.2 0.0 0.0054 16.0 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIK40375.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KIK40375.1 - 0.044 13.8 0.1 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KIK40375.1 - 0.047 14.3 0.0 1.7 9.2 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK40375.1 - 0.063 12.3 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 KIK40375.1 - 0.075 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KIK40375.1 - 0.1 11.8 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KIK40375.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.18 KIK40375.1 - 0.12 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 KIK40375.1 - 0.14 12.6 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KIK40377.1 - 6e-61 206.6 0.0 7.8e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KIK40379.1 - 1.3e-70 238.4 0.0 1.6e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK40379.1 - 3.2e-05 23.3 0.0 0.003 16.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK40379.1 - 0.00011 21.0 0.1 0.00085 18.1 0.1 2.0 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KIK40379.1 - 0.00014 22.4 0.1 0.11 13.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK40379.1 - 0.00063 19.9 0.0 0.0015 18.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIK40379.1 - 0.00086 18.5 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIK40379.1 - 0.00095 18.8 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KIK40379.1 - 0.0081 15.4 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIK40379.1 - 0.012 14.5 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_7 PF13241.6 KIK40379.1 - 0.014 15.8 0.0 0.032 14.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Thi4 PF01946.17 KIK40379.1 - 0.022 14.0 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 KIK40379.1 - 0.025 14.8 0.0 0.056 13.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.22 KIK40379.1 - 0.029 13.4 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KIK40379.1 - 0.044 13.1 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KIK40379.1 - 0.062 12.6 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KIK40379.1 - 0.12 12.1 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 KIK40379.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KIK40379.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KIK40379.1 - 0.19 11.7 0.1 0.54 10.2 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding JAB PF01398.21 KIK40381.1 - 3.7e-30 104.3 0.1 6.8e-30 103.5 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KIK40381.1 - 1.4e-29 102.8 2.7 3e-29 101.8 2.7 1.6 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KIK40381.1 - 0.0004 20.2 0.0 0.00067 19.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain CENP-H PF05837.12 KIK40381.1 - 0.076 13.4 1.0 0.16 12.4 1.0 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Ribosomal_L18A PF01775.17 KIK40382.1 - 5e-55 184.8 0.2 6.1e-55 184.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A DUF4097 PF13349.6 KIK40383.1 - 0.018 14.4 0.1 0.16 11.3 0.1 2.4 1 1 0 1 1 1 0 Putative adhesin Molydop_binding PF01568.21 KIK40383.1 - 0.077 13.0 0.1 12 6.0 0.0 2.6 2 0 0 2 2 2 0 Molydopterin dinucleotide binding domain Pro_isomerase PF00160.21 KIK40385.1 - 9.2e-46 156.0 0.1 1e-45 155.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3930 PF13067.6 KIK40388.1 - 0.11 12.7 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3930) GPI-anchored PF10342.9 KIK40389.1 - 9.7e-06 26.3 2.8 1.7e-05 25.5 2.8 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RRM_1 PF00076.22 KIK40394.1 - 1e-19 70.1 0.0 2.2e-11 43.4 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK40394.1 - 0.0017 18.5 0.0 0.24 11.6 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif DUF4140 PF13600.6 KIK40394.1 - 1.5 9.3 0.0 1.5 9.3 0.0 2.8 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Med3 PF11593.8 KIK40396.1 - 0.0038 16.5 3.9 0.0049 16.1 3.9 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal RPA_interact_N PF14766.6 KIK40396.1 - 2.4 7.9 9.2 0.34 10.6 3.8 2.1 2 0 0 2 2 2 0 Replication protein A interacting N-terminal Amidase PF01425.21 KIK40399.1 - 6e-88 295.8 0.0 7.4e-88 295.5 0.0 1.1 1 0 0 1 1 1 1 Amidase Rad60-SLD_2 PF13881.6 KIK40400.1 - 6.7e-15 55.2 0.0 1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KIK40400.1 - 0.0012 18.6 0.0 0.0035 17.1 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin family Glyco_transf_90 PF05686.12 KIK40401.1 - 9e-16 57.8 0.4 6e-14 51.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 90 Sugar_tr PF00083.24 KIK40403.1 - 1.4e-82 277.9 23.3 1.6e-82 277.7 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK40403.1 - 7.6e-11 41.5 38.6 3.3e-06 26.3 13.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KIK40403.1 - 6.6e-06 24.9 26.0 0.0033 16.0 1.3 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein Glyco_hydro_16 PF00722.21 KIK40404.1 - 0.00049 19.6 0.1 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 APG6_N PF17675.1 KIK40406.1 - 8.3e-06 26.4 7.1 1.2e-05 25.9 7.1 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region GAS PF13851.6 KIK40406.1 - 0.0033 16.8 4.4 0.0044 16.4 4.4 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding FUSC PF04632.12 KIK40406.1 - 0.0097 14.5 4.1 0.012 14.2 4.1 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family BicD PF09730.9 KIK40406.1 - 0.019 13.5 5.6 0.024 13.1 5.6 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Dict-STAT-coil PF09267.10 KIK40406.1 - 0.034 14.5 4.0 0.06 13.7 4.0 1.4 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil Tup_N PF08581.10 KIK40406.1 - 0.041 14.2 3.2 0.068 13.5 0.7 2.1 1 1 1 2 2 2 0 Tup N-terminal YojJ PF10372.9 KIK40406.1 - 0.042 13.9 0.5 0.1 12.7 0.2 1.7 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus CASP_C PF08172.12 KIK40406.1 - 0.075 12.4 7.4 0.059 12.7 2.1 2.0 1 1 1 2 2 2 0 CASP C terminal 4HB_MCP_1 PF12729.7 KIK40406.1 - 0.084 12.4 0.4 0.11 12.0 0.4 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction TMF_TATA_bd PF12325.8 KIK40406.1 - 0.15 12.3 4.9 0.26 11.5 4.9 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding SKA2 PF16740.5 KIK40406.1 - 0.16 11.8 6.3 1 9.2 5.9 2.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Snapin_Pallidin PF14712.6 KIK40406.1 - 0.2 12.1 9.8 0.32 11.4 1.2 2.2 1 1 1 2 2 2 0 Snapin/Pallidin SlyX PF04102.12 KIK40406.1 - 0.3 11.7 10.4 0.086 13.5 4.9 2.2 1 1 1 2 2 2 0 SlyX UPF0242 PF06785.11 KIK40406.1 - 0.82 9.7 6.5 1.3 9.1 6.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 KIK40406.1 - 0.95 10.1 3.2 2 9.1 3.2 1.7 1 1 0 1 1 1 0 Initiation control protein YabA WXG100 PF06013.12 KIK40406.1 - 1.9 8.8 5.3 17 5.7 5.3 2.1 1 1 0 1 1 1 0 Proteins of 100 residues with WXG DivIC PF04977.15 KIK40406.1 - 2.8 7.8 10.4 2.4 8.0 2.7 2.3 1 1 1 2 2 2 0 Septum formation initiator ZapB PF06005.12 KIK40406.1 - 6.8 7.2 10.7 1.6 9.2 2.6 1.9 1 1 1 2 2 2 0 Cell division protein ZapB DUF2968 PF11180.8 KIK40406.1 - 7.4 6.2 11.9 11 5.6 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) SNF2_N PF00176.23 KIK40408.1 - 6.7e-52 176.3 1.1 1.2e-51 175.5 1.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK40408.1 - 4.7e-13 49.4 0.0 1.6e-12 47.8 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 KIK40408.1 - 1.2e-10 41.3 3.8 2.7e-10 40.1 3.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIK40408.1 - 1.5e-09 37.6 6.3 2.9e-09 36.6 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK40408.1 - 2.4e-09 36.9 3.0 2.4e-09 36.9 3.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK40408.1 - 1.4e-07 31.7 6.6 3.9e-07 30.3 6.6 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIK40408.1 - 2.8e-07 30.3 6.8 8.4e-07 28.8 6.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK40408.1 - 1.3e-06 28.2 5.6 2.8e-06 27.2 5.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KIK40408.1 - 7e-06 26.1 5.5 1.8e-05 24.8 5.5 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING ResIII PF04851.15 KIK40408.1 - 2.1e-05 24.6 0.0 5.6e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SPT6_acidic PF14632.6 KIK40408.1 - 0.0007 20.1 16.9 0.0007 20.1 16.9 3.1 3 0 0 3 3 2 1 Acidic N-terminal SPT6 zf-RING_11 PF17123.5 KIK40408.1 - 0.0024 17.6 4.8 0.0056 16.4 4.8 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KIK40408.1 - 0.012 15.9 3.5 0.034 14.4 3.5 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KIK40408.1 - 0.012 15.4 7.6 0.16 11.9 7.6 2.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 FYVE PF01363.21 KIK40408.1 - 0.02 15.1 2.6 0.045 13.9 2.6 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-Nse PF11789.8 KIK40408.1 - 0.038 13.8 2.6 0.087 12.7 2.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Tmpp129 PF10272.9 KIK40408.1 - 0.083 12.2 1.8 0.14 11.4 1.8 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-RING_4 PF14570.6 KIK40408.1 - 0.16 11.8 5.9 0.41 10.5 5.9 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 KIK40408.1 - 0.44 10.6 3.6 1.2 9.3 3.6 1.7 1 0 0 1 1 1 0 Double zinc ribbon Helicase_C PF00271.31 KIK40414.1 - 3.4e-06 27.4 0.8 5.4e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Plavaka PF18759.1 KIK40415.1 - 6.5e-36 124.2 0.0 1.1e-35 123.4 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase SIR2 PF02146.17 KIK40418.1 - 5.2e-47 160.0 0.0 6.6e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Sir2 family HEAT_EZ PF13513.6 KIK40419.1 - 1.3e-19 70.2 7.8 2.8e-08 34.1 0.1 7.5 6 1 1 7 7 6 4 HEAT-like repeat Importin_rep_4 PF18808.1 KIK40419.1 - 8.8e-19 67.6 0.4 3.5e-18 65.7 0.1 2.3 2 0 0 2 2 1 1 Importin repeat HEAT PF02985.22 KIK40419.1 - 2.7e-10 39.6 12.3 6.2e-05 22.9 0.1 8.2 8 0 0 8 8 7 1 HEAT repeat Vac14_Fab1_bd PF12755.7 KIK40419.1 - 3.3e-09 37.2 0.8 5.8e-05 23.6 0.0 4.2 4 1 1 5 5 4 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 KIK40419.1 - 3.3e-08 33.5 0.4 0.0048 16.7 0.0 4.2 2 2 1 3 3 3 2 rRNA processing/ribosome biogenesis HEAT_2 PF13646.6 KIK40419.1 - 1.7e-07 31.5 8.7 0.0077 16.6 0.0 6.6 5 1 2 7 7 7 2 HEAT repeats DUF3385 PF11865.8 KIK40419.1 - 1.1e-06 28.6 0.0 0.26 11.2 0.0 4.0 2 1 1 3 3 3 2 Domain of unknown function (DUF3385) Cnd1 PF12717.7 KIK40419.1 - 0.0004 20.5 0.2 0.0025 17.9 0.0 2.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KIK40419.1 - 0.00047 18.9 0.8 0.012 14.2 0.1 3.2 3 1 1 4 4 4 2 Adaptin N terminal region MMS19_C PF12460.8 KIK40419.1 - 0.0051 16.0 0.0 0.0051 16.0 0.0 3.1 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal Importin_rep_6 PF18829.1 KIK40419.1 - 0.0054 16.8 0.0 0.042 14.0 0.0 2.5 2 0 0 2 2 2 1 Importin repeat 6 Cnd3 PF12719.7 KIK40419.1 - 0.0072 15.5 0.2 2.5 7.2 0.0 3.1 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain DUF4042 PF13251.6 KIK40419.1 - 0.028 14.1 1.8 5.3 6.7 0.0 3.7 4 1 0 4 4 4 0 Domain of unknown function (DUF4042) Npa1 PF11707.8 KIK40419.1 - 0.048 13.0 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal RTP1_C1 PF10363.9 KIK40419.1 - 0.073 13.3 0.3 31 4.8 0.0 4.0 4 1 1 5 5 4 0 Required for nuclear transport of RNA pol II C-terminus 1 G-alpha PF00503.20 KIK40420.1 - 8.3e-109 364.0 1.6 1e-108 363.7 1.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK40420.1 - 1.9e-15 56.7 0.8 7.8e-10 38.5 0.2 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIK40420.1 - 3.6e-05 23.2 0.2 0.23 10.8 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KIK40420.1 - 0.00056 20.1 0.2 0.18 12.0 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 KIK40420.1 - 0.0096 15.2 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin MMR_HSR1 PF01926.23 KIK40420.1 - 0.03 14.4 0.1 9.2 6.4 0.0 2.7 1 1 1 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KIK40420.1 - 0.073 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain CFEM PF05730.11 KIK40421.1 - 1e-08 35.2 13.9 2.1e-08 34.2 13.9 1.5 1 0 0 1 1 1 1 CFEM domain Miga PF10265.9 KIK40421.1 - 5.2 5.9 5.8 5.7 5.8 5.8 1.1 1 0 0 1 1 1 0 Mitoguardin CFEM PF05730.11 KIK40422.1 - 5.8e-08 32.7 20.1 1.2e-07 31.7 20.1 1.5 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.20 KIK40422.1 - 0.021 15.1 1.3 0.055 13.7 1.3 1.6 1 0 0 1 1 1 0 Gamma-thionin family DUF485 PF04341.12 KIK40427.1 - 0.0088 16.0 1.3 0.023 14.6 1.3 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF485 zf-CCCH PF00642.24 KIK40429.1 - 9.6e-08 31.8 2.3 1.9e-07 30.8 2.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KIK40429.1 - 8.4e-05 22.3 2.1 8.4e-05 22.3 2.1 1.7 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KIK40429.1 - 0.0051 16.8 3.9 0.01 15.9 3.9 1.6 1 0 0 1 1 1 1 Zinc finger domain DUF2025 PF09634.10 KIK40429.1 - 0.088 12.8 0.1 2.5 8.2 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2025) zf-CCCH_2 PF14608.6 KIK40429.1 - 0.25 11.9 0.3 0.25 11.9 0.3 1.7 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Lactonase PF10282.9 KIK40430.1 - 5.7e-39 134.3 0.0 7.1e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller CoA_transf_3 PF02515.17 KIK40431.1 - 2.5e-107 359.2 0.0 2.9e-107 359.0 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Tim29 PF10171.9 KIK40432.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 SARAF PF06682.12 KIK40433.1 - 2.4e-61 208.2 0.0 2.8e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF2615 PF11027.8 KIK40433.1 - 0.21 11.7 0.0 0.38 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) adh_short PF00106.25 KIK40434.1 - 2e-31 109.0 0.0 2.5e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK40434.1 - 1.6e-16 60.6 0.1 2.2e-16 60.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK40434.1 - 2.1e-09 37.6 0.8 3.8e-09 36.7 0.8 1.3 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KIK40434.1 - 0.0081 16.1 0.3 0.018 15.0 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Epimerase PF01370.21 KIK40434.1 - 0.017 14.6 0.0 0.88 9.0 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KIK40434.1 - 0.031 14.2 0.1 0.064 13.1 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KIK40434.1 - 0.047 13.7 0.0 0.52 10.3 0.0 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus THF_DHG_CYH_C PF02882.19 KIK40434.1 - 0.048 13.0 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 KIK40434.1 - 0.091 11.8 0.1 0.15 11.1 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Exog_C PF18026.1 KIK40434.1 - 0.093 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain Glyco_trans_4_3 PF12000.8 KIK40434.1 - 0.13 11.9 0.0 0.38 10.4 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 4 group NAD_binding_10 PF13460.6 KIK40434.1 - 0.18 11.6 1.5 0.43 10.5 1.5 1.6 1 1 0 1 1 1 0 NAD(P)H-binding Myb_DNA-bind_3 PF12776.7 KIK40436.1 - 0.001 20.0 0.4 0.0015 19.5 0.4 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KIK40436.1 - 0.021 15.2 0.5 0.13 12.7 0.5 2.2 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF3746 PF12562.8 KIK40437.1 - 0.064 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3746) HTH_Tnp_4 PF13613.6 KIK40438.1 - 0.0069 16.1 0.2 0.0085 15.8 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DUF2157 PF09925.9 KIK40438.1 - 0.034 13.9 0.1 0.036 13.8 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF3382 PF11862.8 KIK40438.1 - 0.092 13.0 0.0 0.11 12.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) Bac_DnaA_C PF08299.11 KIK40438.1 - 0.15 12.1 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix HTH_23 PF13384.6 KIK40438.1 - 0.2 11.5 0.0 0.24 11.3 0.0 1.1 1 0 0 1 1 1 0 Homeodomain-like domain GerE PF00196.19 KIK40438.1 - 0.2 11.2 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Helicase_C PF00271.31 KIK40440.1 - 7.8e-11 42.3 0.1 2.9e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RabGAP-TBC PF00566.18 KIK40442.1 - 2.3e-38 132.0 0.0 3.5e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Adaptin_N PF01602.20 KIK40443.1 - 3.1e-18 65.6 5.4 1.8e-17 63.1 5.4 2.4 1 1 0 1 1 1 1 Adaptin N terminal region T2SSE_N PF05157.15 KIK40444.1 - 0.05 13.9 0.1 0.19 12.0 0.0 1.9 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein E, N-terminal domain Aldo_ket_red PF00248.21 KIK40444.1 - 0.14 11.4 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Aldo/keto reductase family Cellulase PF00150.18 KIK40446.1 - 3.6e-30 105.4 3.7 5.9e-30 104.7 3.7 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FAM72 PF14976.6 KIK40447.1 - 9.1e-17 61.6 8.1 1e-15 58.1 8.1 2.1 1 1 0 1 1 1 1 FAM72 protein Nop25 PF09805.9 KIK40448.1 - 4.2e-22 79.1 6.2 4.2e-22 79.1 6.2 2.2 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) DUF4551 PF15087.6 KIK40448.1 - 5.3 5.7 8.4 6.5 5.5 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) V-SNARE_C PF12352.8 KIK40449.1 - 4.8e-15 55.6 1.6 6.1e-15 55.3 0.5 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KIK40449.1 - 3e-07 30.3 0.1 1.6e-06 27.9 0.0 2.1 2 1 1 3 3 3 1 Sec20 EMC3_TMCO1 PF01956.16 KIK40449.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.5 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Plasmid_RAQPRD PF09686.10 KIK40449.1 - 0.15 12.2 2.2 0.74 10.1 1.1 2.4 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) E1-E2_ATPase PF00122.20 KIK40450.1 - 9.1e-30 103.5 0.0 2e-29 102.4 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 KIK40450.1 - 5.8e-24 84.6 0.0 1.6e-23 83.1 0.0 1.8 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 KIK40450.1 - 2.2e-18 67.3 0.1 2.7e-06 27.8 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KIK40450.1 - 4e-09 36.5 4.9 1.1e-08 35.0 4.9 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KIK40450.1 - 5e-06 26.5 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KIK40450.1 - 0.00017 21.2 0.0 0.00038 20.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF2569 PF10754.9 KIK40450.1 - 0.013 15.9 1.0 0.013 15.9 1.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Hydrolase_3 PF08282.12 KIK40450.1 - 0.21 11.3 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ribosomal_L11_N PF03946.14 KIK40452.1 - 1e-23 82.9 0.1 1.5e-23 82.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KIK40452.1 - 5.6e-18 65.2 0.1 9.7e-18 64.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Amidohydro_2 PF04909.14 KIK40454.1 - 3e-05 24.0 0.1 5.5e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Amidohydrolase Yae1_N PF09811.9 KIK40455.1 - 9.1e-08 31.7 22.5 3.3e-05 23.5 9.5 2.7 1 1 2 3 3 3 3 Essential protein Yae1, N terminal Alanine_zipper PF11839.8 KIK40455.1 - 0.059 13.7 15.2 0.37 11.2 2.5 2.4 1 1 1 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein HAP1_N PF04849.13 KIK40455.1 - 0.075 12.2 16.0 0.11 11.6 16.0 1.3 1 1 0 1 1 1 0 HAP1 N-terminal conserved region SlyX PF04102.12 KIK40455.1 - 0.62 10.7 8.1 0.44 11.2 2.2 2.5 2 0 0 2 2 2 0 SlyX DUF3584 PF12128.8 KIK40455.1 - 0.96 6.9 18.8 1.2 6.6 18.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Csm1_N PF18504.1 KIK40455.1 - 1 9.7 9.1 0.12 12.7 3.2 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain Spc7 PF08317.11 KIK40455.1 - 1.2 8.0 13.4 2 7.2 13.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein LPP PF04728.13 KIK40455.1 - 1.5 9.3 12.2 0.33 11.4 2.0 2.9 2 1 0 2 2 2 0 Lipoprotein leucine-zipper eIF3_N PF09440.10 KIK40455.1 - 2 8.8 0.0 2 8.8 0.0 2.6 1 1 2 3 3 3 0 eIF3 subunit 6 N terminal domain XhlA PF10779.9 KIK40455.1 - 2.1 8.6 4.6 2.3 8.5 1.6 2.3 2 0 0 2 2 2 0 Haemolysin XhlA V_ATPase_I PF01496.19 KIK40455.1 - 4.3 5.1 11.5 2.6 5.9 10.0 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Pox_A_type_inc PF04508.12 KIK40455.1 - 5.4 7.0 8.3 0.29 11.1 1.6 2.5 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat SNase PF00565.17 KIK40456.1 - 7.6e-61 203.3 1.3 9e-21 74.4 0.0 6.2 6 0 0 6 6 6 6 Staphylococcal nuclease homologue TUDOR PF00567.24 KIK40456.1 - 5.5e-20 71.6 0.0 1.3e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 KIK40456.1 - 0.0032 17.9 0.1 0.026 15.0 0.0 2.6 2 0 0 2 2 2 1 Agenet domain F-box-like PF12937.7 KIK40460.1 - 3.9e-10 39.5 0.1 1.4e-09 37.7 0.1 2.0 1 0 0 1 1 1 1 F-box-like TPR_1 PF00515.28 KIK40460.1 - 2.4e-05 23.9 0.1 0.058 13.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK40460.1 - 5.7e-05 22.9 0.1 0.24 11.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK40460.1 - 0.0006 19.8 0.1 11 6.5 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat LRR_1 PF00560.33 KIK40460.1 - 0.00066 19.9 5.4 0.18 12.4 0.1 5.6 6 1 0 6 6 6 1 Leucine Rich Repeat F-box PF00646.33 KIK40460.1 - 0.0084 16.0 2.2 0.012 15.4 0.0 2.4 3 0 0 3 3 3 1 F-box domain TPR_14 PF13428.6 KIK40460.1 - 0.055 14.3 0.9 3.2 8.8 0.1 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK40460.1 - 0.14 11.8 0.0 0.95 9.2 0.0 2.1 2 0 0 2 2 2 0 TPR repeat LRR_6 PF13516.6 KIK40460.1 - 0.28 11.3 3.1 43 4.5 0.1 4.6 5 0 0 5 5 5 0 Leucine Rich repeat HIG_1_N PF04588.13 KIK40464.1 - 0.0013 18.9 0.7 0.0025 18.0 0.7 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF2162 PF09930.9 KIK40464.1 - 0.06 12.7 0.1 0.097 12.1 0.1 1.3 1 0 0 1 1 1 0 Predicted transporter (DUF2162) FAD_binding_3 PF01494.19 KIK40465.1 - 1.3e-19 70.7 0.0 2.7e-19 69.6 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIK40465.1 - 9.6e-09 35.3 4.2 4e-05 23.4 1.5 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK40465.1 - 3.7e-08 32.9 0.4 0.0003 20.1 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK40465.1 - 8.1e-07 29.2 0.1 1.9e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIK40465.1 - 9.3e-06 26.1 0.2 0.0032 18.0 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KIK40465.1 - 2.4e-05 23.8 1.1 0.0035 16.7 0.2 2.6 2 1 1 3 3 3 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KIK40465.1 - 2.7e-05 23.7 0.3 5.6e-05 22.7 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KIK40465.1 - 0.00012 21.5 0.4 0.011 15.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK40465.1 - 0.00012 21.3 2.5 0.00012 21.3 2.5 2.3 2 1 1 3 3 3 1 FAD binding domain HI0933_like PF03486.14 KIK40465.1 - 0.00027 19.8 0.5 0.037 12.7 0.2 2.6 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 KIK40465.1 - 0.029 13.5 0.2 0.05 12.7 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KIK40465.1 - 0.19 10.5 2.6 5.5 5.7 0.6 2.8 3 0 0 3 3 3 0 Tryptophan halogenase FAD-oxidase_C PF02913.19 KIK40466.1 - 6.5e-59 199.6 0.0 1.3e-58 198.6 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KIK40466.1 - 2.6e-30 105.0 0.1 4.9e-30 104.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Hydantoinase_B PF02538.14 KIK40467.1 - 2.8e-210 699.1 0.6 3.2e-210 698.9 0.6 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Aminotran_5 PF00266.19 KIK40468.1 - 2.6e-41 141.8 0.0 3.3e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V CHAT PF12770.7 KIK40468.1 - 0.02 14.3 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 CHAT domain DUF982 PF06169.12 KIK40468.1 - 0.02 14.9 0.1 0.064 13.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF982) PRF PF06875.11 KIK40469.1 - 0.095 12.1 0.1 0.1 12.0 0.1 1.0 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF Gp_dh_N PF00044.24 KIK40469.1 - 0.13 12.6 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain PHD PF00628.29 KIK40470.1 - 8.3e-06 25.6 3.5 8.3e-06 25.6 3.5 4.1 5 0 0 5 5 5 1 PHD-finger Acyl-CoA_dh_M PF02770.19 KIK40471.1 - 0.00045 20.3 0.0 0.00096 19.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain MFS_1 PF07690.16 KIK40473.1 - 2.6e-22 79.2 46.4 4.3e-17 62.1 22.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily WH1 PF00568.23 KIK40475.1 - 1e-26 93.0 0.1 1.4e-26 92.6 0.1 1.1 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 KIK40475.1 - 3.5e-08 33.7 0.1 1.5e-07 31.6 0.1 2.0 2 0 0 2 2 2 1 P21-Rho-binding domain DCP1 PF06058.13 KIK40475.1 - 0.00017 21.5 0.0 0.00025 21.0 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family WH2 PF02205.20 KIK40475.1 - 0.096 12.5 0.1 0.3 11.0 0.1 1.9 1 0 0 1 1 1 0 WH2 motif ARS2 PF04959.13 KIK40475.1 - 0.54 10.6 3.4 1.7 9.0 3.4 1.8 1 0 0 1 1 1 0 Arsenite-resistance protein 2 EF-hand_1 PF00036.32 KIK40476.1 - 4.7e-43 141.6 12.1 4e-10 38.5 0.7 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KIK40476.1 - 2.5e-36 124.0 2.2 2.1e-18 66.5 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KIK40476.1 - 5.9e-32 109.3 10.8 2.7e-13 49.5 0.1 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KIK40476.1 - 2.2e-31 105.1 6.3 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KIK40476.1 - 2.4e-27 93.2 8.2 2.3e-06 26.8 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KIK40476.1 - 1.6e-15 57.1 0.2 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KIK40476.1 - 2.6e-10 40.2 0.4 7.3e-05 22.7 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KIK40476.1 - 3.4e-08 33.8 0.0 0.0035 17.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KIK40476.1 - 4.3e-06 26.7 0.1 0.042 13.9 0.0 3.4 3 1 1 4 4 3 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 KIK40476.1 - 3.3e-05 24.7 0.0 0.022 15.6 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain EFhand_Ca_insen PF08726.10 KIK40476.1 - 8.7e-05 22.5 0.8 0.00049 20.1 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 KIK40476.1 - 0.00028 21.0 6.3 0.027 14.7 1.0 3.1 1 1 3 4 4 4 2 Dockerin type I domain DUF1103 PF06513.11 KIK40476.1 - 0.00052 19.7 1.8 0.0006 19.5 1.8 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.13 KIK40476.1 - 0.00084 19.3 0.6 0.43 10.5 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein Poly_export PF02563.16 KIK40476.1 - 0.0027 17.9 0.1 0.41 10.9 0.0 3.0 1 1 0 2 2 2 1 Polysaccharide biosynthesis/export protein DUF3349 PF11829.8 KIK40476.1 - 0.0033 18.2 0.1 1.5 9.7 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) TerB PF05099.13 KIK40476.1 - 0.0042 17.1 0.2 0.46 10.4 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB DUF4497 PF14924.6 KIK40476.1 - 0.0046 17.4 0.0 1.6 9.2 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) RNA_pol_Rpb4 PF03874.16 KIK40476.1 - 0.0091 16.3 0.2 6.4 7.1 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb4 SurA_N_2 PF13623.6 KIK40476.1 - 0.031 14.1 0.5 2 8.3 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF5580 PF17743.1 KIK40476.1 - 0.033 12.7 0.0 0.033 12.7 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 KIK40476.1 - 0.036 14.4 0.1 9.8 6.6 0.0 2.4 1 1 0 2 2 2 0 EF-hand domain MotA_activ PF09114.10 KIK40476.1 - 0.037 14.2 0.7 0.49 10.5 0.1 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain Fe_hyd_lg_C PF02906.14 KIK40476.1 - 0.055 13.1 0.3 0.095 12.4 0.3 1.5 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain AAA_22 PF13401.6 KIK40478.1 - 4.2e-07 30.3 0.0 8.2e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KIK40478.1 - 2.2e-05 24.2 0.0 5.8e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIK40478.1 - 0.0034 17.8 0.1 0.016 15.6 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KIK40478.1 - 0.0057 15.9 0.0 0.0088 15.3 0.0 1.3 1 1 0 1 1 1 1 NB-ARC domain DUF815 PF05673.13 KIK40478.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 KIK40478.1 - 0.015 15.8 0.1 0.035 14.6 0.1 1.5 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 KIK40478.1 - 0.028 14.1 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF87 PF01935.17 KIK40478.1 - 0.029 14.5 0.0 0.082 13.0 0.0 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 KIK40478.1 - 0.03 14.4 0.0 0.14 12.3 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK40478.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 KIK40478.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Serpentine_r_xa PF03383.15 KIK40480.1 - 0.007 16.4 2.2 0.007 16.4 2.2 2.1 2 0 0 2 2 2 1 Caenorhabditis serpentine receptor-like protein, class xa DUF2070 PF09843.9 KIK40480.1 - 0.73 8.1 13.2 1 7.6 13.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TPR_12 PF13424.6 KIK40484.1 - 2.8e-08 33.9 19.5 0.15 12.3 2.2 5.1 4 1 0 5 5 5 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK40484.1 - 1.3e-07 31.3 7.1 0.0087 15.5 0.2 3.7 3 1 1 4 4 4 3 MalT-like TPR region TPR_16 PF13432.6 KIK40484.1 - 6e-06 26.8 5.5 0.0026 18.4 0.2 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK40484.1 - 0.0018 18.2 1.6 5 7.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Herpes_UL51 PF04540.13 KIK40484.1 - 0.0056 16.4 0.1 0.0095 15.7 0.1 1.3 1 0 0 1 1 1 1 Herpesvirus UL51 protein TPR_8 PF13181.6 KIK40484.1 - 0.007 16.5 7.3 3 8.3 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK40484.1 - 0.01 16.6 14.1 3.6 8.6 0.1 5.3 3 2 3 6 6 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIK40484.1 - 0.012 16.2 10.9 0.39 11.5 0.0 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK40484.1 - 0.013 15.6 18.3 0.096 12.9 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK40484.1 - 0.023 15.2 12.0 6.4 7.4 0.3 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK40484.1 - 0.035 14.3 0.9 2.2 8.6 0.0 3.3 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4398 PF14346.6 KIK40484.1 - 0.041 14.5 1.5 12 6.6 0.1 3.0 3 0 0 3 3 2 0 Domain of unknown function (DUF4398) TPR_1 PF00515.28 KIK40484.1 - 0.12 12.3 8.2 3 7.8 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIK40487.1 - 6.9e-09 35.9 11.9 0.0058 16.9 1.4 4.7 4 1 0 4 4 3 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK40487.1 - 2.6e-06 27.1 6.3 0.011 15.1 1.7 3.4 2 1 1 3 3 3 3 MalT-like TPR region AAA_22 PF13401.6 KIK40487.1 - 4.8e-06 26.9 0.0 2.9e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIK40487.1 - 7.4e-05 23.2 0.0 0.00043 20.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain TPR_2 PF07719.17 KIK40487.1 - 0.00014 21.7 4.2 0.53 10.5 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK40487.1 - 0.00052 20.5 7.2 0.046 14.2 0.1 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.22 KIK40487.1 - 0.0015 17.8 0.0 0.0028 16.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Herpes_UL51 PF04540.13 KIK40487.1 - 0.0015 18.3 0.2 0.0038 17.0 0.2 1.7 1 0 0 1 1 1 1 Herpesvirus UL51 protein ABC_tran PF00005.27 KIK40487.1 - 0.0085 16.6 0.0 0.023 15.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter TPR_14 PF13428.6 KIK40487.1 - 0.012 16.4 9.6 1.6 9.7 0.0 5.1 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK40487.1 - 0.013 15.2 6.5 1.4 8.9 0.0 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat AAA PF00004.29 KIK40487.1 - 0.017 15.5 0.0 0.053 14.0 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KIK40487.1 - 0.027 14.4 0.0 0.068 13.1 0.0 1.7 1 1 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 KIK40487.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Vinculin PF01044.19 KIK40487.1 - 0.075 11.3 1.2 0.12 10.6 0.2 1.6 2 0 0 2 2 2 0 Vinculin family DUF87 PF01935.17 KIK40487.1 - 0.078 13.1 0.4 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain TPR_4 PF07721.14 KIK40487.1 - 0.11 13.2 0.1 77 4.4 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ABC_trans_aux PF03886.13 KIK40489.1 - 0.0065 16.1 0.1 0.0083 15.7 0.1 1.1 1 0 0 1 1 1 1 ABC-type transport auxiliary lipoprotein component Ery_res_leader1 PF08051.11 KIK40489.1 - 0.039 13.9 0.0 0.093 12.8 0.0 1.6 1 0 0 1 1 1 0 Erythromycin resistance leader peptide MAP65_ASE1 PF03999.12 KIK40491.1 - 2.3e-69 234.7 2.3 2e-65 221.7 0.4 2.3 2 0 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) Rx_N PF18052.1 KIK40491.1 - 0.31 11.4 1.8 0.72 10.2 0.1 2.5 2 0 0 2 2 2 0 Rx N-terminal domain Apolipoprotein PF01442.18 KIK40491.1 - 0.49 10.2 8.4 0.088 12.7 0.3 3.0 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain GvpL_GvpF PF06386.11 KIK40491.1 - 1.5 8.7 8.5 1.4 8.8 4.3 2.4 2 1 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF ATP-synt_ab PF00006.25 KIK40492.1 - 6.2e-63 212.3 0.0 1.1e-62 211.5 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KIK40492.1 - 7.1e-22 77.7 1.5 7.1e-22 77.7 1.5 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 KIK40492.1 - 0.0054 16.0 0.8 0.012 14.9 0.1 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 KIK40492.1 - 0.023 15.1 0.2 0.42 11.0 0.0 2.7 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KIK40492.1 - 0.029 14.3 0.1 0.067 13.1 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KIK40492.1 - 0.03 14.7 0.1 0.085 13.2 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KIK40492.1 - 0.035 14.0 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 KIK40492.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ATPase PF06745.13 KIK40492.1 - 0.057 12.8 0.1 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 KIK40492.1 - 0.075 13.4 0.6 0.31 11.4 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIK40492.1 - 0.076 12.7 0.4 1.4 8.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain T3SS_ATPase_C PF18269.1 KIK40492.1 - 0.28 11.1 0.7 1.2 9.0 0.7 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain DUF1744 PF08490.12 KIK40493.1 - 8.4e-135 449.4 0.0 1.4e-134 448.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KIK40493.1 - 3.7e-71 240.0 0.0 6.1e-71 239.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KIK40493.1 - 6.4e-11 41.6 0.2 2.4e-08 33.1 0.1 3.7 3 1 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KIK40493.1 - 5.1e-07 29.6 0.4 2.1e-06 27.6 0.4 1.9 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KIK40493.1 - 0.0036 17.3 0.0 0.012 15.6 0.0 1.9 1 0 0 1 1 1 1 RNase_H superfamily Toxin_28 PF08115.11 KIK40493.1 - 0.29 11.0 1.5 0.33 10.9 0.1 1.8 2 0 0 2 2 2 0 SFI toxin family RIFIN PF02009.16 KIK40495.1 - 0.052 13.4 1.5 0.072 13.0 1.5 1.1 1 0 0 1 1 1 0 Rifin Herpes_US12 PF05363.12 KIK40495.1 - 0.091 13.5 0.3 0.23 12.2 0.3 1.7 1 0 0 1 1 1 0 Herpesvirus US12 family HNF-1_N PF04814.13 KIK40495.1 - 0.14 12.8 1.3 0.21 12.2 1.3 1.2 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Cauli_VI PF01693.16 KIK40496.1 - 0.002 18.4 0.1 0.0029 17.9 0.1 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin KDZ PF18758.1 KIK40497.1 - 8e-66 221.8 0.1 1.4e-65 221.1 0.1 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK40497.1 - 4.5e-43 145.8 0.5 8.7e-43 144.9 0.0 1.8 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK40497.1 - 3.5e-05 23.9 0.0 0.00015 21.9 0.0 2.1 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK40497.1 - 0.034 14.0 0.0 0.034 14.0 0.0 2.0 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases ABC_tran_CTD PF16326.5 KIK40497.1 - 0.16 12.2 8.7 0.32 11.3 0.4 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain Nexin_C PF08628.12 KIK40501.1 - 0.0017 18.9 0.2 0.039 14.5 0.0 3.1 3 0 0 3 3 3 1 Sorting nexin C terminal DUF294_C PF10335.9 KIK40501.1 - 0.043 13.6 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain OTU PF02338.19 KIK40502.1 - 4.4e-19 69.2 0.0 1.9e-18 67.1 0.0 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KIK40502.1 - 0.00024 20.6 0.0 0.025 14.0 0.0 2.8 2 1 0 2 2 2 1 Peptidase C65 Otubain NIL PF09383.10 KIK40502.1 - 0.097 12.5 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 NIL domain DUF4407 PF14362.6 KIK40502.1 - 2.9 7.2 9.4 3.9 6.7 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Adaptin_N PF01602.20 KIK40503.1 - 9.1e-125 417.2 4.2 1.2e-124 416.8 4.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KIK40503.1 - 2.4e-58 196.7 3.1 6.8e-55 185.5 0.3 2.4 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIK40503.1 - 3.5e-14 52.9 12.1 8e-08 32.6 0.4 5.6 4 1 2 6 6 6 4 HEAT repeats HEAT PF02985.22 KIK40503.1 - 1.8e-10 40.2 7.2 0.068 13.5 0.0 6.7 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.6 KIK40503.1 - 0.00013 22.4 1.4 14 6.4 0.0 5.7 6 0 0 6 6 6 1 HEAT-like repeat Arm PF00514.23 KIK40503.1 - 0.00015 21.6 1.5 0.73 10.0 0.0 5.2 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KIK40503.1 - 0.00084 19.5 0.5 3.5 7.9 0.0 4.0 3 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KIK40503.1 - 0.0016 18.0 0.0 0.026 14.1 0.0 2.5 2 0 0 2 2 2 1 CLASP N terminal U3snoRNP10 PF12397.8 KIK40503.1 - 0.063 13.6 0.0 0.26 11.7 0.0 2.0 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 UNC45-central PF11701.8 KIK40503.1 - 0.13 12.2 0.7 8.4 6.3 0.0 3.1 3 1 1 4 4 4 0 Myosin-binding striated muscle assembly central DUF4477 PF14780.6 KIK40504.1 - 1.7e-15 57.2 0.4 2.6e-15 56.5 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) Cu_bind_like PF02298.17 KIK40505.1 - 6.4e-06 26.1 0.4 1.4e-05 25.0 0.4 1.5 1 0 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.20 KIK40505.1 - 0.001 19.5 0.2 0.0027 18.1 0.2 1.7 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Ribosomal_L37 PF08561.10 KIK40507.1 - 0.055 14.0 0.2 0.1 13.2 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 Pyr_redox_2 PF07992.14 KIK40508.1 - 5.1e-11 42.4 0.0 3.2e-07 29.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK40508.1 - 0.0063 16.1 0.6 1.5 8.3 0.3 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIK40508.1 - 0.021 14.8 0.2 16 5.5 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Malic_M PF03949.15 KIK40508.1 - 0.029 13.6 0.1 0.048 12.9 0.1 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain MSC PF09402.10 KIK40509.1 - 4.5e-90 302.5 0.0 5.8e-90 302.2 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KIK40509.1 - 1e-10 41.2 0.0 2e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain UEV PF05743.13 KIK40510.1 - 3.4e-35 120.5 0.0 5.4e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KIK40510.1 - 6.7e-28 96.4 1.4 2e-27 94.9 0.3 2.2 2 0 0 2 2 2 1 Vps23 core domain TEA PF01285.18 KIK40511.1 - 1.1e-11 44.6 1.5 1.9e-11 43.9 0.9 1.8 2 0 0 2 2 2 1 TEA/ATTS domain DUF1799 PF08809.11 KIK40511.1 - 0.065 13.4 0.2 0.13 12.5 0.2 1.4 1 0 0 1 1 1 0 Phage related hypothetical protein (DUF1799) NOC3p PF07540.11 KIK40512.1 - 3e-32 110.9 0.4 1.3e-31 108.9 0.0 2.3 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 KIK40512.1 - 6.4e-19 68.6 0.2 2.6e-18 66.6 0.0 2.1 2 0 0 2 2 2 1 CBF/Mak21 family DNA_pol3_beta PF00712.19 KIK40512.1 - 0.011 15.9 0.1 0.03 14.4 0.1 1.7 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain DUF4337 PF14235.6 KIK40512.1 - 0.64 10.1 4.2 1.4 9.0 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) BSP_II PF05432.11 KIK40512.1 - 5.2 6.7 20.3 0.5 10.0 6.2 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) ANAPC5 PF12862.7 KIK40513.1 - 6.2e-11 42.2 0.0 2.2e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_10 PF13374.6 KIK40513.1 - 0.00015 21.5 0.2 0.0025 17.6 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIK40513.1 - 0.063 13.6 2.0 1.1 9.6 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat CLASP_N PF12348.8 KIK40514.1 - 1.7e-30 106.3 0.3 1.7e-10 40.9 0.1 5.4 5 0 0 5 5 5 4 CLASP N terminal Cnd1 PF12717.7 KIK40514.1 - 2e-11 44.2 0.3 0.018 15.1 0.0 7.2 6 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KIK40514.1 - 4.9e-07 29.5 21.1 0.41 11.0 0.0 10.4 13 0 0 13 13 11 3 HEAT repeat HEAT_2 PF13646.6 KIK40514.1 - 3.8e-06 27.2 26.3 0.59 10.6 0.0 10.4 8 3 5 13 13 13 3 HEAT repeats RTP1_C1 PF10363.9 KIK40514.1 - 6.3e-06 26.4 0.3 0.049 13.8 0.0 4.3 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 TAN PF11640.8 KIK40514.1 - 0.00018 21.7 6.0 0.69 10.0 0.0 4.6 4 1 0 4 4 4 2 Telomere-length maintenance and DNA damage repair HEAT_EZ PF13513.6 KIK40514.1 - 0.0034 17.8 8.5 3.2 8.4 0.0 6.4 6 1 1 7 7 7 2 HEAT-like repeat TIP120 PF08623.10 KIK40514.1 - 0.01 15.7 0.0 0.46 10.2 0.0 3.3 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) Nipped-B_C PF12830.7 KIK40514.1 - 0.023 14.7 0.4 6.5 6.6 0.0 3.0 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus Arm PF00514.23 KIK40514.1 - 0.2 11.7 0.7 63 3.8 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.9 KIK40514.1 - 0.24 9.9 0.9 0.61 8.5 0.1 2.1 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit DUF1804 PF08822.11 KIK40515.1 - 0.26 11.3 0.8 0.46 10.5 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) COX16 PF14138.6 KIK40516.1 - 10 6.7 7.9 16 6.1 7.9 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 HTH_Tnp_Tc5 PF03221.16 KIK40518.1 - 1e-09 38.3 0.0 1.6e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 KIK40518.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain CENP-B_N PF04218.13 KIK40518.1 - 0.018 14.7 0.0 0.048 13.3 0.0 1.8 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain KDZ PF18758.1 KIK40521.1 - 4.5e-20 72.2 5.9 5.7e-15 55.5 3.7 2.0 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase zf-CCHC PF00098.23 KIK40523.1 - 4.9e-06 26.4 2.0 1e-05 25.3 2.0 1.6 1 0 0 1 1 1 1 Zinc knuckle SEEEED PF14797.6 KIK40523.1 - 0.0087 16.2 8.3 0.0087 16.2 8.3 4.4 3 1 0 4 4 4 1 Serine-rich region of AP3B1, clathrin-adaptor complex FKBP_N PF01346.18 KIK40523.1 - 0.28 12.2 2.9 1.4 9.9 2.9 2.2 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase FlgT_N PF16548.5 KIK40523.1 - 0.73 10.4 4.3 0.76 10.4 0.4 2.7 3 0 0 3 3 3 0 Flagellar assembly protein T, N-terminal domain DUF4378 PF14309.6 KIK40523.1 - 1.2 9.5 5.1 0.24 11.8 0.4 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4378) DUF3813 PF12758.7 KIK40523.1 - 4.2 7.8 6.1 0.47 10.8 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) C_Hendra PF16821.5 KIK40523.1 - 6.6 6.6 9.7 0.87 9.4 2.7 2.5 2 0 0 2 2 2 0 C protein from hendra and measles viruses KDZ PF18758.1 KIK40526.1 - 9.3e-15 54.8 0.0 1e-14 54.7 0.0 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase zf-RVT PF13966.6 KIK40531.1 - 0.0017 19.0 2.2 0.0027 18.4 2.2 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.24 KIK40532.1 - 0.00022 21.4 0.1 0.0053 16.9 0.0 2.1 2 0 0 2 2 2 2 RNase H RVT_1 PF00078.27 KIK40533.1 - 4e-07 29.8 0.0 4.1e-07 29.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 KIK40535.1 - 0.017 15.2 2.0 0.017 15.2 2.0 2.2 2 0 0 2 2 2 0 Zinc knuckle Dimer_Tnp_hAT PF05699.14 KIK40536.1 - 3e-14 52.6 0.1 4.1e-14 52.1 0.1 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Dimer_Tnp_hAT PF05699.14 KIK40540.1 - 3.7e-12 45.9 0.0 4.7e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DEAD PF00270.29 KIK40541.1 - 4e-44 150.5 0.0 1.4e-43 148.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK40541.1 - 9e-27 93.6 0.0 3.7e-26 91.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK40541.1 - 8.2e-06 25.9 0.0 0.00011 22.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KIK40541.1 - 0.12 11.6 0.1 0.12 11.6 0.1 2.2 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase SAM_DrpA PF18255.1 KIK40541.1 - 0.13 12.5 0.0 0.4 10.9 0.0 1.8 2 0 0 2 2 2 0 DNA processing protein A sterile alpha motif domain Lipase_GDSL_3 PF14606.6 KIK40541.1 - 0.3 11.2 1.0 0.57 10.3 0.0 1.9 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Rsc14 PF08586.10 KIK40541.1 - 0.57 11.0 2.8 1.5 9.7 2.8 1.7 1 0 0 1 1 1 0 RSC complex, Rsc14/Ldb7 subunit 6PF2K PF01591.18 KIK40542.1 - 3.3e-69 232.6 0.1 4.5e-69 232.2 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KIK40542.1 - 1e-38 133.0 0.0 2.6e-38 131.7 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KIK40542.1 - 8.2e-08 32.5 0.0 1.4e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KIK40542.1 - 0.0083 15.6 0.0 0.016 14.7 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 KIK40542.1 - 0.038 14.4 0.0 0.07 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PIG-X PF08320.12 KIK40543.1 - 1.1e-23 84.2 0.1 1.3e-23 84.0 0.1 1.0 1 0 0 1 1 1 1 PIG-X / PBN1 Ras PF00071.22 KIK40544.1 - 9.1e-54 181.4 0.0 1e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK40544.1 - 5.3e-22 78.3 0.0 7.6e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK40544.1 - 4.1e-06 26.4 0.0 1.4e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KIK40544.1 - 0.0091 15.9 0.0 0.6 10.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 KIK40544.1 - 0.025 13.9 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GnsAB_toxin PF08178.11 KIK40544.1 - 0.11 12.4 0.1 0.29 11.1 0.1 1.6 2 0 0 2 2 2 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system AAA_16 PF13191.6 KIK40544.1 - 0.12 12.7 0.0 0.32 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Gpi1 PF05024.15 KIK40546.1 - 5.6e-58 196.1 7.6 5.6e-58 196.1 7.6 1.6 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) RGCC PF15151.6 KIK40547.1 - 0.084 13.1 1.7 0.18 12.0 1.7 1.6 1 0 0 1 1 1 0 Response gene to complement 32 protein family ParB PF08775.10 KIK40547.1 - 0.16 12.4 2.2 0.38 11.3 1.1 1.9 2 0 0 2 2 2 0 ParB family zf-RING_14 PF17978.1 KIK40548.1 - 0.16 12.4 1.6 5.9 7.4 0.3 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Dehyd-heme_bind PF09098.10 KIK40549.1 - 2.8e-05 23.8 0.5 6.3e-05 22.7 0.5 1.7 1 0 0 1 1 1 1 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding Peptidase_M75 PF09375.10 KIK40549.1 - 0.0063 16.0 1.8 0.014 14.8 1.8 1.6 1 1 0 1 1 1 1 Imelysin B PF02216.16 KIK40549.1 - 0.047 13.7 0.2 0.13 12.3 0.1 1.8 2 0 0 2 2 2 0 B domain Phi-29_GP16_7 PF06720.11 KIK40549.1 - 0.059 13.2 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 HMG_box_2 PF09011.10 KIK40549.1 - 0.11 13.1 1.3 16 6.1 0.0 2.8 3 0 0 3 3 3 0 HMG-box domain HTH_22 PF13309.6 KIK40549.1 - 0.13 12.3 0.7 1.9 8.6 0.4 2.5 2 0 0 2 2 2 0 HTH domain RNA_pol_Rpb1_5 PF04998.17 KIK40549.1 - 0.14 11.6 1.3 0.22 10.9 1.3 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DEK_C PF08766.11 KIK40549.1 - 0.28 11.1 1.6 0.47 10.4 0.3 2.1 2 0 0 2 2 2 0 DEK C terminal domain HMG_box PF00505.19 KIK40549.1 - 1.5 9.3 5.4 19 5.8 0.3 2.7 2 1 0 2 2 2 0 HMG (high mobility group) box DUF1104 PF06518.11 KIK40549.1 - 5.7 7.4 11.0 1.6 9.1 2.8 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1104) Cauli_VI PF01693.16 KIK40551.1 - 0.038 14.3 0.1 0.065 13.5 0.1 1.4 1 0 0 1 1 1 0 Caulimovirus viroplasmin KDZ PF18758.1 KIK40552.1 - 1.3e-81 273.5 0.1 2e-81 272.8 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase tRNA_bind_3 PF17176.4 KIK40552.1 - 0.049 13.9 1.9 0.093 13.0 0.4 2.2 2 0 0 2 2 2 0 tRNA-binding domain CxC1 PF18802.1 KIK40552.1 - 0.12 12.6 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases Kdo PF06293.14 KIK40554.1 - 0.00017 21.0 0.1 0.00029 20.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HIT PF01230.23 KIK40555.1 - 1.2e-20 74.1 0.1 2e-20 73.3 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KIK40555.1 - 1.9e-10 41.3 0.0 2.8e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KIK40555.1 - 0.027 14.3 0.1 0.084 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 ArAE_2 PF10334.9 KIK40556.1 - 1.4e-54 185.4 0.2 7.5e-54 183.0 0.0 2.1 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 KIK40556.1 - 6.1e-43 147.5 16.4 2.3e-42 145.6 13.3 3.0 2 1 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KIK40556.1 - 2.7e-09 37.2 13.0 2.7e-09 37.2 13.0 3.3 2 1 2 4 4 4 1 Fusaric acid resistance protein-like Homeodomain PF00046.29 KIK40558.1 - 0.093 12.6 0.2 0.11 12.3 0.2 1.1 1 0 0 1 1 1 0 Homeodomain NMT1_2 PF13379.6 KIK40558.1 - 0.096 12.4 0.1 0.1 12.2 0.1 1.0 1 0 0 1 1 1 0 NMT1-like family CorA PF01544.18 KIK40559.1 - 4.2e-14 52.6 5.5 1.1e-13 51.2 5.5 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Pkinase PF00069.25 KIK40560.1 - 8.2e-49 166.3 0.0 1.9e-46 158.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK40560.1 - 2.4e-27 95.8 0.0 3.4e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIK40560.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ECH_1 PF00378.20 KIK40561.1 - 2.5e-37 128.5 0.0 3.1e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIK40561.1 - 1.8e-19 70.4 0.0 1.7e-16 60.7 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Aldedh PF00171.22 KIK40562.1 - 6.3e-187 621.7 0.6 7.1e-187 621.5 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIK40562.1 - 0.0075 15.4 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) WD40 PF00400.32 KIK40564.1 - 9e-40 133.9 24.9 1.1e-07 32.4 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40564.1 - 2.7e-14 53.2 0.9 0.0071 16.6 0.1 5.2 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK40564.1 - 0.001 17.8 0.4 0.57 8.7 0.0 3.6 2 2 2 5 5 5 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK40564.1 - 0.0058 15.6 0.0 13 4.6 0.0 4.0 2 2 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KIK40564.1 - 0.076 11.7 0.2 0.27 9.9 0.1 2.2 2 1 0 2 2 2 0 Nup133 N terminal like DUF3558 PF12079.8 KIK40564.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) WD40 PF00400.32 KIK40565.1 - 9.7e-35 118.0 20.8 8.4e-08 32.8 0.0 7.3 6 1 1 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40565.1 - 4.2e-13 49.4 0.9 0.0049 17.1 0.1 5.3 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK40565.1 - 0.01 14.5 0.1 1.4 7.5 0.0 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK40565.1 - 0.011 14.7 0.1 21 3.9 0.0 3.8 2 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Sugar_tr PF00083.24 KIK40567.1 - 3.2e-93 313.1 20.1 5.3e-93 312.3 20.1 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK40567.1 - 1.6e-20 73.3 41.8 7e-15 54.8 10.8 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily PADR1 PF08063.12 KIK40568.1 - 0.014 15.2 0.1 0.023 14.5 0.1 1.4 1 0 0 1 1 1 0 PADR1 (NUC008) domain CorA PF01544.18 KIK40570.1 - 7.3e-15 55.0 2.4 1.5e-14 54.0 2.4 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Metallophos PF00149.28 KIK40571.1 - 1.5e-06 28.9 0.2 2.1e-06 28.4 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIK40571.1 - 0.073 13.3 0.0 0.18 12.0 0.0 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain WD40 PF00400.32 KIK40574.1 - 5.5e-39 131.5 25.7 5.6e-08 33.3 0.0 7.5 6 1 1 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40574.1 - 7.6e-13 48.6 0.7 0.042 14.2 0.0 5.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WW PF00397.26 KIK40574.1 - 2.4e-05 24.3 1.8 2.4e-05 24.3 1.8 2.4 2 0 0 2 2 2 1 WW domain Nup160 PF11715.8 KIK40574.1 - 0.00047 18.9 0.5 0.31 9.6 0.1 3.3 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK40574.1 - 0.083 11.8 0.1 95 1.8 0.0 3.9 2 2 3 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KIK40574.1 - 0.18 10.5 0.2 1.4 7.6 0.0 2.4 2 1 1 3 3 3 0 Nup133 N terminal like WD40 PF00400.32 KIK40575.1 - 2e-13 50.5 0.2 6e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40575.1 - 0.00096 19.4 0.0 0.26 11.6 0.0 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK40575.1 - 0.0063 15.2 0.0 0.0063 15.2 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Transp_cyt_pur PF02133.15 KIK40576.1 - 4.8e-12 45.4 1.2 2e-07 30.1 1.8 2.0 2 0 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.15 KIK40577.1 - 1.3e-06 27.5 1.1 1.7e-06 27.1 1.1 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Peptidase_C50 PF03568.17 KIK40578.1 - 2.3e-137 458.3 0.0 5.2e-137 457.2 0.0 1.6 2 0 0 2 2 2 1 Peptidase family C50 TPR_12 PF13424.6 KIK40578.1 - 2.3e-05 24.6 16.7 0.13 12.6 3.1 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIK40578.1 - 0.032 14.4 0.4 6.3 7.3 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat CHAT PF12770.7 KIK40578.1 - 0.035 13.5 0.0 0.57 9.5 0.0 2.5 1 1 0 1 1 1 0 CHAT domain TPR_MalT PF17874.1 KIK40578.1 - 0.05 13.0 3.7 0.46 9.8 1.1 3.4 4 1 0 4 4 4 0 MalT-like TPR region TPR_2 PF07719.17 KIK40578.1 - 0.45 10.8 9.5 4.1 7.8 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIK40578.1 - 8.7 6.4 7.4 60 3.7 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Sugar_tr PF00083.24 KIK40579.1 - 2.2e-20 73.0 19.3 1.5e-19 70.2 19.3 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK40579.1 - 1.2e-15 57.4 45.5 5.3e-09 35.4 26.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily QSregVF_b PF12843.7 KIK40581.1 - 0.00099 19.0 0.6 0.14 12.0 0.0 2.8 3 0 0 3 3 3 2 Putative quorum-sensing-regulated virulence factor HNH_3 PF13392.6 KIK40581.1 - 0.014 15.1 0.6 12 5.7 0.0 4.0 5 0 0 5 5 5 0 HNH endonuclease DUF4663 PF15668.5 KIK40583.1 - 0.13 11.3 0.0 0.15 11.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) DNApol_Exo PF18136.1 KIK40584.1 - 2.9e-104 348.2 0.4 4.8e-104 347.5 0.4 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KIK40584.1 - 9.6e-48 163.1 0.0 2.1e-47 162.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family A Cellulase PF00150.18 KIK40588.1 - 1.6e-13 50.8 0.0 2.5e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Tudor_2 PF18104.1 KIK40591.1 - 0.09 12.5 0.1 0.22 11.2 0.1 1.7 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain Acetyltransf_1 PF00583.25 KIK40593.1 - 1.3e-12 48.0 0.0 1.7e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK40593.1 - 9.5e-08 32.0 0.0 1.1e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK40593.1 - 1.2e-06 28.9 0.0 1.7e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK40593.1 - 8.9e-06 25.6 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 KIK40593.1 - 0.00014 21.4 0.8 0.00019 21.0 0.8 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase SBF PF01758.16 KIK40594.1 - 6.8e-50 169.5 14.4 6.8e-50 169.5 14.4 2.1 3 0 0 3 3 3 1 Sodium Bile acid symporter family Methyltransf_31 PF13847.6 KIK40595.1 - 2.5e-24 85.8 0.0 4.3e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK40595.1 - 8.7e-21 74.4 0.0 1.7e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK40595.1 - 3e-19 69.5 0.0 6e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK40595.1 - 3.5e-14 52.7 0.0 6.8e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KIK40595.1 - 4.4e-11 43.4 0.0 8.3e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK40595.1 - 4.7e-10 39.6 0.0 8.7e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KIK40595.1 - 1.2e-08 34.7 0.1 1.9e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Rhodanese PF00581.20 KIK40595.1 - 1.1e-07 32.4 0.1 2.6e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 Rhodanese-like domain PCMT PF01135.19 KIK40595.1 - 8.7e-07 28.9 0.1 1.7e-06 27.9 0.1 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 KIK40595.1 - 2.8e-06 26.8 0.0 3.7e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KIK40595.1 - 7.8e-06 25.5 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KIK40595.1 - 0.001 18.4 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DOT1 PF08123.13 KIK40595.1 - 0.0063 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 UPF0020 PF01170.18 KIK40595.1 - 0.026 14.2 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_PK PF05891.12 KIK40595.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_8 PF05148.15 KIK40595.1 - 0.069 13.0 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase NNMT_PNMT_TEMT PF01234.17 KIK40595.1 - 0.12 11.5 0.1 13 4.8 0.0 2.2 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family N6_N4_Mtase PF01555.18 KIK40595.1 - 0.13 11.9 0.0 4.1 7.0 0.0 2.2 2 0 0 2 2 2 0 DNA methylase HMG_box PF00505.19 KIK40596.1 - 6.3e-12 45.7 0.3 1.1e-11 45.0 0.3 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK40596.1 - 0.025 15.2 0.1 0.05 14.2 0.1 1.5 1 0 0 1 1 1 0 HMG-box domain CHAT PF12770.7 KIK40598.1 - 2.3e-32 112.6 0.0 5.1e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 KIK40598.1 - 0.00096 19.4 14.2 6.5 7.1 0.1 7.3 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 KIK40598.1 - 0.014 15.3 6.4 0.95 9.4 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Peptidase_C25 PF01364.18 KIK40598.1 - 0.027 13.7 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C25 TPR_7 PF13176.6 KIK40598.1 - 0.044 13.8 0.6 29 5.0 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Adeno_hexon PF01065.19 KIK40598.1 - 0.09 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain PP-binding PF00550.25 KIK40599.1 - 2.2e-13 50.4 0.7 3.2e-13 49.8 0.7 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KIK40599.1 - 1.5e-06 28.4 0.7 2.1e-06 27.9 0.7 1.2 1 0 0 1 1 1 1 Acyl-carrier GST_N_2 PF13409.6 KIK40600.1 - 1.5e-05 25.2 0.0 3.5e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIK40600.1 - 0.00035 20.9 0.0 0.00077 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK40600.1 - 0.066 13.6 0.0 0.26 11.7 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIK40600.1 - 0.066 13.4 0.0 2.9 8.1 0.0 2.5 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Ribosomal_L13 PF00572.18 KIK40601.1 - 6.7e-11 42.5 0.1 1.8e-08 34.7 0.0 2.5 2 1 1 3 3 3 2 Ribosomal protein L13 KH_1 PF00013.29 KIK40602.1 - 2.4e-41 139.4 10.8 4.6e-16 58.4 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KIK40602.1 - 5.9e-11 42.1 0.8 0.0034 17.2 0.1 3.7 3 1 1 4 4 4 3 KH domain KH_2 PF07650.17 KIK40602.1 - 2.5e-09 36.8 7.2 0.0066 16.3 0.3 3.5 4 0 0 4 4 4 3 KH domain KH_5 PF13184.6 KIK40602.1 - 1.2e-05 25.3 4.6 0.042 14.0 0.1 3.5 3 0 0 3 3 3 2 NusA-like KH domain DAZAP2 PF11029.8 KIK40602.1 - 0.0099 16.8 0.2 0.015 16.2 0.2 1.4 1 0 0 1 1 1 1 DAZ associated protein 2 (DAZAP2) dUTPase PF00692.19 KIK40602.1 - 0.1 12.3 0.5 8.5 6.1 0.1 2.4 2 0 0 2 2 2 0 dUTPase Ribosomal_L17 PF01196.19 KIK40603.1 - 1.4e-34 118.8 0.1 3.1e-34 117.8 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L17 ADH_N PF08240.12 KIK40605.1 - 2.3e-30 104.7 1.4 2.7e-30 104.5 0.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK40605.1 - 4.4e-11 42.9 0.2 8.2e-09 35.5 0.2 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KIK40605.1 - 0.00019 20.8 0.0 0.00035 20.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain QRPTase_C PF01729.19 KIK40605.1 - 0.021 14.6 0.0 0.069 12.9 0.0 1.7 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain TrkA_N PF02254.18 KIK40605.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain F-box PF00646.33 KIK40607.1 - 0.055 13.4 0.4 0.24 11.3 0.2 2.2 2 0 0 2 2 2 0 F-box domain UPF0114 PF03350.16 KIK40608.1 - 0.013 15.7 0.0 0.033 14.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 Tetraspanin PF00335.20 KIK40608.1 - 0.062 13.0 4.6 0.097 12.4 4.6 1.5 1 1 0 1 1 1 0 Tetraspanin family E1_DerP2_DerF2 PF02221.15 KIK40609.1 - 1.8e-25 89.9 0.1 2.1e-25 89.7 0.1 1.1 1 0 0 1 1 1 1 ML domain Enolase_C PF00113.22 KIK40609.1 - 0.057 12.7 0.2 0.12 11.6 0.1 1.5 1 1 0 1 1 1 0 Enolase, C-terminal TIM barrel domain Ipi1_N PF12333.8 KIK40610.1 - 1.6e-24 86.4 0.3 2.3e-22 79.5 0.0 3.5 2 1 2 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation KNOX1 PF03790.13 KIK40610.1 - 0.17 11.6 0.1 0.41 10.4 0.1 1.5 1 0 0 1 1 1 0 KNOX1 domain DPBB_1 PF03330.18 KIK40611.1 - 7.5e-10 39.0 0.3 2e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Lytic transglycolase Cerato-platanin PF07249.12 KIK40611.1 - 0.032 14.3 0.1 0.059 13.5 0.1 1.4 1 0 0 1 1 1 0 Cerato-platanin SOG2 PF10428.9 KIK40611.1 - 0.24 10.5 15.0 0.27 10.4 15.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SWI-SNF_Ssr4 PF08549.10 KIK40611.1 - 6.3 5.3 6.2 8 5.0 6.2 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) JAB PF01398.21 KIK40612.1 - 1.3e-14 54.2 0.0 2.3e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DevR PF01905.16 KIK40612.1 - 0.094 11.8 0.6 1.8 7.5 0.6 2.5 1 1 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 MDMPI_N PF11716.8 KIK40612.1 - 0.25 12.0 1.9 0.66 10.7 0.0 2.3 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain Cation_efflux PF01545.21 KIK40613.1 - 6.6e-52 176.1 9.9 1.6e-51 174.9 9.9 1.6 1 1 0 1 1 1 1 Cation efflux family MASE4 PF17158.4 KIK40613.1 - 1.7 7.9 8.5 0.063 12.5 2.0 1.9 2 1 0 2 2 2 0 Membrane-associated sensor, integral membrane domain NPCC PF08058.11 KIK40613.1 - 5.4 7.1 6.4 3.4 7.7 1.3 2.4 2 0 0 2 2 2 0 Nuclear pore complex component Med5 PF08689.10 KIK40614.1 - 1.1e-09 36.8 0.0 9e-09 33.8 0.0 2.1 2 0 0 2 2 2 2 Mediator complex subunit Med5 GRIP PF01465.20 KIK40616.1 - 3.5e-16 58.8 0.4 8.9e-16 57.5 0.4 1.8 1 0 0 1 1 1 1 GRIP domain Fez1 PF06818.15 KIK40616.1 - 0.67 10.4 74.7 0.086 13.3 28.5 5.0 1 1 3 4 4 4 0 Fez1 Baculo_PEP_C PF04513.12 KIK40616.1 - 1.1 9.3 25.3 0.14 12.2 1.0 5.2 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pex14_N PF04695.13 KIK40617.1 - 3.3e-20 73.3 6.5 3.3e-20 73.3 6.5 3.0 2 2 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region ING PF12998.7 KIK40617.1 - 0.0026 18.3 4.6 0.0048 17.5 4.1 1.7 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Golgin_A5 PF09787.9 KIK40617.1 - 0.0096 15.4 9.2 0.017 14.6 9.2 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 5 zf-C4H2 PF10146.9 KIK40617.1 - 0.014 15.7 0.5 0.014 15.7 0.5 1.7 2 0 0 2 2 2 0 Zinc finger-containing protein DUF2524 PF10732.9 KIK40617.1 - 0.018 15.3 4.0 0.018 15.3 4.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2524) Spc7 PF08317.11 KIK40617.1 - 0.024 13.5 9.8 0.043 12.7 9.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 KIK40617.1 - 0.024 12.6 0.2 0.028 12.4 0.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LXG PF04740.12 KIK40617.1 - 0.026 14.2 5.8 0.058 13.1 5.8 1.5 1 0 0 1 1 1 0 LXG domain of WXG superfamily NPV_P10 PF05531.12 KIK40617.1 - 0.032 14.7 9.1 0.29 11.6 2.6 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein IFT57 PF10498.9 KIK40617.1 - 0.039 12.9 9.6 0.13 11.2 9.6 1.7 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF3584 PF12128.8 KIK40617.1 - 0.085 10.4 9.2 0.13 9.8 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) LMBR1 PF04791.16 KIK40617.1 - 0.091 11.7 0.4 0.12 11.3 0.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF812 PF05667.11 KIK40617.1 - 0.13 11.1 9.6 0.23 10.3 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Allexi_40kDa PF05549.11 KIK40617.1 - 0.15 11.5 0.8 0.22 11.0 0.1 1.7 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF4191 PF13829.6 KIK40617.1 - 0.17 11.2 1.4 0.27 10.5 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Prominin PF05478.11 KIK40617.1 - 0.19 9.7 1.1 0.26 9.2 1.1 1.1 1 0 0 1 1 1 0 Prominin Med9 PF07544.13 KIK40617.1 - 0.25 11.4 7.9 0.96 9.6 7.8 2.1 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Vps54_N PF10475.9 KIK40617.1 - 0.32 10.2 3.6 0.53 9.5 3.6 1.3 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Vpu PF00558.19 KIK40617.1 - 0.36 10.6 3.4 0.8 9.5 3.4 1.5 1 0 0 1 1 1 0 Vpu protein MCPsignal PF00015.21 KIK40617.1 - 0.39 10.5 7.8 0.077 12.8 4.3 1.6 2 0 0 2 2 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Mt_ATP-synt_D PF05873.12 KIK40617.1 - 0.53 10.1 9.3 0.2 11.5 3.0 2.4 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) FAP206 PF12018.8 KIK40617.1 - 0.58 9.6 4.6 1.1 8.7 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function Rsd_AlgQ PF04353.13 KIK40617.1 - 0.63 10.0 4.3 0.4 10.6 1.4 2.0 1 1 1 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Tektin PF03148.14 KIK40617.1 - 0.66 8.7 11.1 2 7.1 11.1 1.7 1 1 0 1 1 1 0 Tektin family DUF948 PF06103.11 KIK40617.1 - 1.2 9.5 5.3 12 6.2 5.3 2.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Zw10 PF06248.13 KIK40617.1 - 1.3 7.5 8.4 1.8 7.0 8.4 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Laminin_II PF06009.12 KIK40617.1 - 1.3 9.0 12.4 0.27 11.2 8.6 1.7 2 0 0 2 2 2 0 Laminin Domain II Exonuc_VII_L PF02601.15 KIK40617.1 - 1.6 8.2 5.9 2.5 7.6 5.9 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 KIK40617.1 - 1.8 7.7 7.8 4.5 6.4 7.8 1.6 1 1 0 1 1 1 0 TMPIT-like protein DUF4199 PF13858.6 KIK40617.1 - 1.9 8.9 3.1 11 6.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) Spectrin PF00435.21 KIK40617.1 - 2.4 8.7 11.3 0.11 12.9 2.4 2.7 2 1 1 3 3 3 0 Spectrin repeat ApoLp-III PF07464.11 KIK40617.1 - 2.7 8.1 14.2 3.4 7.7 9.1 2.7 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) YabA PF06156.13 KIK40617.1 - 2.9 8.6 8.8 28 5.4 8.8 2.2 1 1 0 1 1 1 0 Initiation control protein YabA DUF1664 PF07889.12 KIK40617.1 - 4.6 7.3 13.3 0.91 9.6 7.3 2.7 3 1 0 3 3 2 0 Protein of unknown function (DUF1664) Rx_N PF18052.1 KIK40617.1 - 5.4 7.4 7.6 11 6.3 4.8 2.7 1 1 1 2 2 2 0 Rx N-terminal domain YkuI_C PF10388.9 KIK40617.1 - 5.7 6.7 7.3 11 5.7 0.0 2.9 2 1 1 3 3 3 0 EAL-domain associated signalling protein domain DUF1319 PF07028.11 KIK40617.1 - 9.3 6.5 9.8 40 4.5 7.6 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF1319) GTP_EFTU PF00009.27 KIK40618.1 - 3.1e-57 193.3 0.3 4.9e-57 192.6 0.3 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KIK40618.1 - 2.3e-28 98.7 0.7 3.6e-28 98.1 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KIK40618.1 - 9.9e-16 57.9 3.5 2.5e-15 56.6 3.5 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIK40618.1 - 4.3e-05 23.6 0.1 8.9e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK40618.1 - 0.0032 17.4 0.1 0.0068 16.3 0.0 1.5 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 KIK40618.1 - 0.0095 15.7 0.2 3.8 7.3 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KIK40618.1 - 0.017 14.7 0.6 0.031 13.9 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GCV_H PF01597.19 KIK40619.1 - 1.2e-39 135.0 0.3 1.4e-39 134.8 0.3 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 KIK40619.1 - 3.4e-06 26.9 0.1 4.9e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 KIK40619.1 - 6.1e-05 22.8 0.5 0.00013 21.8 0.5 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme RNaseH_C PF09293.10 KIK40619.1 - 0.018 15.4 0.1 0.12 12.7 0.1 2.1 1 1 0 1 1 1 0 T4 RNase H, C terminal Peptidase_M23 PF01551.22 KIK40619.1 - 0.053 13.7 0.7 3 8.1 0.1 2.3 1 1 1 2 2 2 0 Peptidase family M23 GP70 PF17429.2 KIK40619.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Gene product 70 ESSS PF10183.9 KIK40620.1 - 2.1e-13 50.4 0.1 2.2e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PDE6_gamma PF04868.12 KIK40620.1 - 0.057 13.7 0.0 0.076 13.3 0.0 1.2 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit p450 PF00067.22 KIK40621.1 - 4.1e-13 48.9 0.0 4.9e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.25 KIK40623.1 - 2.2e-09 37.5 0.0 3.4e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KIK40623.1 - 4e-05 23.5 0.0 6.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KIK40623.1 - 0.00026 20.9 0.0 0.00045 20.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK40623.1 - 0.0015 18.9 0.0 0.0023 18.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RIO1 PF01163.22 KIK40624.1 - 5.9e-46 156.5 0.0 9.9e-46 155.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KIK40624.1 - 7.5e-33 112.6 0.0 1.6e-32 111.5 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 KIK40624.1 - 7.7e-10 39.1 1.6 0.00062 19.8 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KIK40624.1 - 1.4e-06 27.9 0.0 8.5e-06 25.3 0.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Lin-8 PF03353.15 KIK40624.1 - 0.15 11.6 7.6 0.21 11.1 7.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC45 PF02724.14 KIK40624.1 - 2.1 6.6 9.8 2.8 6.1 9.8 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KIK40624.1 - 4.4 6.6 7.1 6.6 6.0 7.1 1.2 1 0 0 1 1 1 0 NOA36 protein ANTH PF07651.16 KIK40626.1 - 0.0058 15.7 0.1 0.0076 15.3 0.1 1.2 1 0 0 1 1 1 1 ANTH domain Hormone_3 PF00159.18 KIK40626.1 - 0.011 15.8 1.1 0.022 14.8 0.1 2.0 2 0 0 2 2 2 0 Pancreatic hormone peptide SMN PF06003.12 KIK40629.1 - 9.8e-09 34.8 1.6 1.3e-08 34.5 1.6 1.1 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Tudor_3 PF18115.1 KIK40629.1 - 0.0013 18.6 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain PWWP PF00855.17 KIK40629.1 - 0.0042 17.5 1.2 0.021 15.2 1.2 2.1 1 1 0 1 1 1 1 PWWP domain TUDOR PF00567.24 KIK40629.1 - 0.0044 17.0 0.0 0.0079 16.2 0.0 1.5 1 1 0 1 1 1 1 Tudor domain RRP36 PF06102.12 KIK40629.1 - 0.0079 16.2 13.5 0.015 15.3 9.6 2.0 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 Pil1 PF13805.6 KIK40630.1 - 5.6e-45 153.9 0.2 8.7e-45 153.3 0.2 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 IF4E PF01652.18 KIK40631.1 - 1.1e-51 174.8 0.0 1.4e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mito_carr PF00153.27 KIK40632.1 - 2.7e-58 193.9 2.0 1.2e-18 66.9 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF296 PF03479.15 KIK40632.1 - 0.0058 17.0 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Plants and Prokaryotes Conserved (PCC) domain PX PF00787.24 KIK40633.1 - 2.4e-16 59.7 0.0 6.9e-16 58.2 0.0 1.8 2 0 0 2 2 2 1 PX domain AICARFT_IMPCHas PF01808.18 KIK40633.1 - 0.00076 19.0 0.1 0.001 18.6 0.1 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme Fez1 PF06818.15 KIK40633.1 - 0.014 15.9 3.7 0.064 13.7 3.7 2.0 1 1 0 1 1 1 0 Fez1 Cobl PF09469.10 KIK40635.1 - 0.11 12.7 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain Aa_trans PF01490.18 KIK40636.1 - 3.3e-28 98.5 33.1 5.9e-28 97.7 33.1 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Prenyltrans PF00432.21 KIK40637.1 - 1.3e-32 111.2 12.0 1.9e-08 33.9 0.0 6.2 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KIK40637.1 - 0.00057 19.1 0.0 0.31 10.1 0.0 2.5 2 0 0 2 2 2 2 Squalene-hopene cyclase N-terminal domain Sacchrp_dh_C PF16653.5 KIK40638.1 - 1.7e-87 293.9 0.0 2.9e-87 293.1 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synth PF01564.17 KIK40638.1 - 2.6e-68 229.2 0.0 5.2e-68 228.2 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Sacchrp_dh_NADP PF03435.18 KIK40638.1 - 1e-25 90.5 0.2 1e-25 90.5 0.2 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Spermine_synt_N PF17284.2 KIK40638.1 - 1.1e-24 86.0 0.6 2.8e-24 84.8 0.1 2.0 2 0 0 2 2 2 1 Spermidine synthase tetramerisation domain Shikimate_DH PF01488.20 KIK40638.1 - 2.3e-07 31.0 0.2 1.8e-06 28.0 0.1 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_25 PF13649.6 KIK40638.1 - 1.6e-06 28.7 0.1 0.00017 22.2 0.0 3.0 3 1 0 3 3 3 1 Methyltransferase domain NAD_binding_10 PF13460.6 KIK40638.1 - 0.0002 21.3 0.1 0.00039 20.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Methyltransf_12 PF08242.12 KIK40638.1 - 0.0024 18.6 0.1 0.075 13.8 0.0 3.1 3 1 0 3 3 3 1 Methyltransferase domain GFO_IDH_MocA PF01408.22 KIK40638.1 - 0.0066 17.3 0.7 0.015 16.2 0.1 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 KIK40638.1 - 0.065 13.3 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus MTS PF05175.14 KIK40638.1 - 0.091 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Semialdhyde_dh PF01118.24 KIK40638.1 - 0.14 12.6 0.1 0.32 11.4 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain HMG_box PF00505.19 KIK40639.1 - 1.2e-12 48.1 1.0 2e-12 47.3 1.0 1.4 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK40639.1 - 0.00019 22.0 0.0 0.00024 21.6 0.0 1.1 1 0 0 1 1 1 1 HMG-box domain Ribosomal_S17e PF00833.18 KIK40639.1 - 0.069 13.1 0.0 0.08 12.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal S17 Sugar_tr PF00083.24 KIK40641.1 - 3.8e-113 378.7 21.5 4.4e-113 378.5 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK40641.1 - 2.6e-21 76.0 30.1 2.6e-21 76.0 30.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TatD_DNase PF01026.21 KIK40642.1 - 8.9e-43 146.5 0.0 1.1e-42 146.2 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase WD40 PF00400.32 KIK40643.1 - 3e-57 189.3 13.3 4.3e-09 36.8 0.1 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40643.1 - 3.4e-16 59.3 1.8 0.13 12.6 0.1 6.5 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK40643.1 - 5.2e-10 39.1 0.0 0.027 13.8 0.0 4.8 4 1 0 4 4 4 2 WD40-like domain Nucleoporin_N PF08801.11 KIK40643.1 - 2.3e-08 33.2 0.4 0.24 10.1 0.0 4.4 1 1 3 5 5 5 3 Nup133 N terminal like PQQ_3 PF13570.6 KIK40643.1 - 2e-06 28.1 0.5 6.7 7.3 0.0 6.6 5 2 2 7 7 7 1 PQQ-like domain Nup160 PF11715.8 KIK40643.1 - 2.2e-06 26.6 0.0 2.1 6.9 0.0 4.3 4 0 0 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.12 KIK40643.1 - 2.6e-06 27.2 1.5 1.5 8.9 0.1 6.4 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat NACHT PF05729.12 KIK40643.1 - 0.0003 20.7 0.9 0.003 17.5 0.9 2.3 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK40643.1 - 0.00058 20.3 0.1 0.0022 18.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Ge1_WD40 PF16529.5 KIK40643.1 - 0.0047 15.9 0.1 8.2 5.3 0.0 4.3 2 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KIK40643.1 - 0.0061 16.2 2.9 0.057 13.0 1.4 2.3 1 1 0 2 2 2 1 PQQ-like domain Me-amine-dh_H PF06433.11 KIK40643.1 - 0.0069 15.3 0.0 0.33 9.8 0.0 2.3 1 1 1 2 2 2 1 Methylamine dehydrogenase heavy chain (MADH) PQQ PF01011.21 KIK40643.1 - 0.0094 15.8 0.0 6.4 6.9 0.0 4.4 4 0 0 4 4 4 1 PQQ enzyme repeat AAA_22 PF13401.6 KIK40643.1 - 0.011 16.0 0.2 0.6 10.4 0.0 3.0 2 1 1 3 3 3 0 AAA domain Parvo_NS1 PF01057.17 KIK40643.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CHAP PF05257.16 KIK40643.1 - 0.85 10.2 7.6 1.7 9.2 0.1 4.3 4 1 1 5 5 4 0 CHAP domain NmrA PF05368.13 KIK40646.1 - 8.7e-14 51.6 0.0 1.1e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK40646.1 - 4.9e-08 33.1 0.0 1.6e-07 31.4 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIK40646.1 - 0.12 11.8 0.0 0.33 10.4 0.0 1.8 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family BTB PF00651.31 KIK40647.1 - 0.0003 21.0 0.0 0.0011 19.2 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain PCNA_N PF00705.18 KIK40648.1 - 1.3e-52 176.8 3.8 3.6e-52 175.4 3.3 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KIK40648.1 - 2.2e-39 134.5 1.5 2.2e-19 69.9 0.0 2.8 3 0 0 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KIK40648.1 - 1.8e-05 24.3 0.1 8.5e-05 22.1 0.0 2.1 2 1 0 2 2 2 1 Rad9 Nop14 PF04147.12 KIK40648.1 - 0.076 11.2 32.7 0.1 10.8 32.7 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KIK40648.1 - 0.13 11.6 32.9 0.18 11.1 32.9 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 KIK40648.1 - 0.13 11.6 37.3 0.19 11.2 37.3 1.1 1 0 0 1 1 1 0 SDA1 RNase_P_pop3 PF08228.11 KIK40648.1 - 0.14 12.3 0.2 0.53 10.3 0.1 2.1 1 1 1 2 2 2 0 RNase P subunit Pop3 Apt1 PF10351.9 KIK40648.1 - 0.34 9.7 11.6 0.53 9.1 11.6 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Merozoite_SPAM PF07133.11 KIK40648.1 - 0.72 9.8 34.4 1.5 8.8 34.4 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Hus1 PF04005.12 KIK40648.1 - 0.99 8.5 0.0 0.99 8.5 0.0 3.4 2 1 1 3 3 2 0 Hus1-like protein SLC12 PF03522.15 KIK40648.1 - 3.2 6.7 11.3 4.2 6.3 11.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 KIK40648.1 - 3.9 6.1 15.1 5.2 5.7 15.1 1.2 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 KIK40648.1 - 6.6 4.7 13.6 8.4 4.4 13.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 KIK40648.1 - 7.9 5.6 11.0 11 5.2 11.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter F-box-like PF12937.7 KIK40650.1 - 1e-06 28.5 1.4 1.5e-06 28.0 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK40650.1 - 0.00013 21.8 1.2 0.00045 20.0 0.1 2.4 2 0 0 2 2 2 1 F-box domain Diphthamide_syn PF01866.17 KIK40651.1 - 2.7e-99 332.5 0.1 3.3e-99 332.2 0.1 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein TPR_1 PF00515.28 KIK40653.1 - 2.2e-40 134.9 5.7 0.00035 20.3 0.0 11.3 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_2 PF07719.17 KIK40653.1 - 2e-30 102.4 12.6 0.00073 19.5 0.0 11.4 11 1 0 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.6 KIK40653.1 - 3.1e-21 73.8 2.3 0.0097 16.1 0.0 9.7 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 KIK40653.1 - 1.1e-19 69.8 5.5 2.3e-07 30.4 0.0 7.3 5 2 2 7 7 7 4 TPR repeat TPR_16 PF13432.6 KIK40653.1 - 3.7e-19 69.1 14.2 1.1e-05 25.9 0.0 7.2 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIK40653.1 - 1.8e-17 63.4 17.9 0.00019 21.6 0.0 9.0 2 2 5 9 9 9 6 Tetratricopeptide repeat TPR_17 PF13431.6 KIK40653.1 - 2.4e-17 62.0 2.0 0.00056 20.1 0.0 8.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 KIK40653.1 - 4.4e-16 59.2 19.6 8e-05 23.1 0.7 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KIK40653.1 - 6.5e-16 57.7 16.8 8.7e-05 23.0 0.0 9.1 7 3 3 10 10 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK40653.1 - 1.1e-11 43.9 4.6 0.052 13.6 0.1 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK40653.1 - 6e-09 36.0 7.8 0.0069 16.6 0.0 5.7 4 2 3 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KIK40653.1 - 1.5e-08 34.6 8.8 0.094 12.9 0.0 6.3 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK40653.1 - 5.9e-08 32.5 5.1 4.8e-05 22.9 0.4 4.1 3 1 2 5 5 5 1 MalT-like TPR region TPR_6 PF13174.6 KIK40653.1 - 1.9e-07 31.2 6.1 0.27 11.9 0.0 7.2 7 1 0 7 7 7 2 Tetratricopeptide repeat NARP1 PF12569.8 KIK40653.1 - 6.5e-05 22.0 4.2 0.0078 15.2 0.0 3.4 2 1 0 3 3 3 1 NMDA receptor-regulated protein 1 DUF3856 PF12968.7 KIK40653.1 - 0.00032 20.8 4.3 1.4 9.0 0.1 5.4 4 2 1 5 5 5 1 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 KIK40653.1 - 0.0034 17.2 23.3 0.39 10.7 0.0 8.0 10 0 0 10 10 9 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIK40653.1 - 0.015 15.4 1.1 4 7.6 0.0 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 KIK40653.1 - 0.015 15.8 0.4 50 4.9 0.0 4.9 6 0 0 6 6 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 KIK40653.1 - 0.027 13.7 11.0 0.14 11.3 0.0 4.4 4 2 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 KIK40653.1 - 0.04 14.3 12.4 1.8 9.0 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF627 PF04781.12 KIK40653.1 - 0.11 12.5 3.2 0.56 10.2 0.0 3.7 4 2 0 4 4 3 0 Protein of unknown function (DUF627) MoCF_biosynth PF00994.24 KIK40654.1 - 1.6e-31 108.9 0.0 2.4e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain Pkinase PF00069.25 KIK40656.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain CinA PF02464.17 KIK40657.1 - 1.4e-29 102.7 0.3 1.8e-29 102.3 0.3 1.0 1 0 0 1 1 1 1 Competence-damaged protein Pkinase_fungal PF17667.1 KIK40658.1 - 0.00024 20.0 0.3 0.00036 19.4 0.3 1.3 1 0 0 1 1 1 1 Fungal protein kinase KOW PF00467.29 KIK40658.1 - 0.2 11.7 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 KOW motif AMP-binding PF00501.28 KIK40660.1 - 4.5e-59 200.1 0.0 6.9e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 KIK40660.1 - 1.8e-29 103.5 0.1 1.6e-28 100.4 0.1 2.2 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 KIK40660.1 - 4.9e-10 39.6 0.0 2.3e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 KIK40660.1 - 0.0001 23.0 0.2 0.00024 21.8 0.2 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.11 KIK40660.1 - 0.0033 17.0 0.0 0.012 15.1 0.0 1.9 2 0 0 2 2 2 1 PE-PPE domain Hydrolase_4 PF12146.8 KIK40660.1 - 0.034 13.4 0.1 0.1 11.9 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Pkinase_fungal PF17667.1 KIK40662.1 - 3.8e-57 193.9 0.0 5.8e-28 97.8 0.0 2.2 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 KIK40662.1 - 2.5e-05 24.3 0.4 8.2e-05 22.6 0.3 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Plavaka PF18759.1 KIK40663.1 - 1.4e-94 316.9 0.1 2.2e-94 316.4 0.1 1.3 1 0 0 1 1 1 1 Plavaka transposase zinc_ribbon_2 PF13240.6 KIK40663.1 - 0.11 12.2 0.3 0.23 11.2 0.3 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2_9 PF16293.5 KIK40663.1 - 0.14 12.0 0.3 0.5 10.3 0.2 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) eIF3m_C_helix PF18005.1 KIK40666.1 - 1.7e-12 46.8 1.0 4.9e-12 45.3 1.0 1.9 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix PCI PF01399.27 KIK40666.1 - 3.7e-11 43.5 0.0 3.7e-10 40.2 0.0 2.5 2 0 0 2 2 2 1 PCI domain GST_N_3 PF13417.6 KIK40667.1 - 8.8e-17 61.3 0.0 1.6e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK40667.1 - 1.3e-14 54.2 0.0 2.9e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK40667.1 - 6.4e-08 32.5 2.4 8.6e-08 32.1 0.1 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KIK40667.1 - 1.5e-06 28.4 0.0 2.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KIK40667.1 - 0.022 15.3 0.0 0.05 14.2 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KIK40667.1 - 0.035 14.3 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin GST_C PF00043.25 KIK40667.1 - 0.14 12.4 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain WD40 PF00400.32 KIK40668.1 - 1.1e-40 136.8 17.5 7.5e-07 29.8 0.5 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40668.1 - 1.8e-11 44.2 0.2 0.019 15.2 0.0 5.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK40668.1 - 9.1e-06 24.6 0.2 0.052 12.2 0.2 3.7 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK40668.1 - 0.0012 18.2 0.0 1.1 8.5 0.0 2.7 2 1 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.9 KIK40668.1 - 0.0041 16.9 0.0 4.1 7.1 0.0 3.1 2 1 0 2 2 2 2 Lipoprotein LpqB beta-propeller domain PD40 PF07676.12 KIK40668.1 - 0.012 15.6 0.2 2.4 8.2 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK40668.1 - 0.064 12.2 0.0 28 3.5 0.0 3.5 2 2 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FtsX PF02687.21 KIK40671.1 - 0.04 14.4 1.3 0.2 12.1 0.0 2.1 2 0 0 2 2 2 0 FtsX-like permease family APH PF01636.23 KIK40673.1 - 5.5e-19 69.0 0.0 8.5e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIK40673.1 - 0.00015 21.4 0.0 0.00025 20.7 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KIK40673.1 - 0.048 13.3 0.1 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 RIO1 family DCP1 PF06058.13 KIK40676.1 - 1.5e-21 76.5 0.0 4.9e-21 74.8 0.0 1.7 2 0 0 2 2 2 1 Dcp1-like decapping family Plasmodium_Vir PF05795.11 KIK40676.1 - 0.18 11.2 0.5 0.41 10.0 0.5 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Pkinase_Tyr PF07714.17 KIK40677.1 - 1.4e-21 76.9 0.0 3.1e-20 72.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK40677.1 - 1.4e-16 60.7 0.0 1.5e-15 57.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK40677.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK40677.1 - 0.04 13.9 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KIK40677.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pmp3 PF01679.17 KIK40680.1 - 2e-11 43.9 11.2 2.9e-11 43.4 11.2 1.3 1 1 0 1 1 1 1 Proteolipid membrane potential modulator Pkinase_Tyr PF07714.17 KIK40681.1 - 2.9e-39 134.9 0.0 3.5e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK40681.1 - 5.1e-32 111.3 0.0 6.3e-32 111.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KIK40681.1 - 0.00074 18.9 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIK40681.1 - 0.0069 16.3 0.0 0.0095 15.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KIK40681.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_S8e PF01201.22 KIK40682.1 - 0.15 12.2 6.7 0.2 11.8 6.7 1.3 1 0 0 1 1 1 0 Ribosomal protein S8e DUF3552 PF12072.8 KIK40682.1 - 2.7 7.4 31.1 2.5 7.5 29.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Glyco_hydro_3_C PF01915.22 KIK40683.1 - 2.4e-54 184.4 0.0 4.7e-54 183.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIK40683.1 - 9.2e-39 133.7 0.0 1.7e-38 132.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIK40683.1 - 5.2e-18 64.9 0.0 1.1e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain WD40 PF00400.32 KIK40684.1 - 7.4e-37 124.7 26.5 1.5e-06 28.8 0.2 7.5 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40684.1 - 1.1e-11 44.9 0.6 0.022 15.0 0.0 5.0 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WW PF00397.26 KIK40684.1 - 0.00013 22.0 0.3 0.00013 22.0 0.3 2.9 3 0 0 3 3 3 1 WW domain Nup160 PF11715.8 KIK40684.1 - 0.0016 17.2 0.1 5 5.6 0.0 3.8 3 1 0 3 3 3 2 Nucleoporin Nup120/160 DUF4231 PF14015.6 KIK40685.1 - 0.11 13.0 2.6 0.51 10.8 2.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) WD40 PF00400.32 KIK40687.1 - 1.9e-40 136.1 21.6 1.2e-07 32.3 1.0 7.4 6 1 1 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40687.1 - 2e-12 47.2 0.8 0.022 15.1 0.1 5.3 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WW PF00397.26 KIK40687.1 - 4.5e-06 26.7 5.6 4.6e-06 26.6 1.4 3.2 3 0 0 3 3 3 1 WW domain Nup160 PF11715.8 KIK40687.1 - 3.9e-05 22.5 0.1 0.022 13.4 0.1 3.3 2 1 1 4 4 4 2 Nucleoporin Nup120/160 betaPIX_CC PF16523.5 KIK40688.1 - 0.012 15.4 0.1 0.021 14.7 0.1 1.3 1 0 0 1 1 1 0 betaPIX coiled coil RRF PF01765.19 KIK40689.1 - 8.7e-27 94.1 2.5 1.3e-26 93.5 2.5 1.2 1 0 0 1 1 1 1 Ribosome recycling factor UbiA PF01040.18 KIK40690.1 - 1.8e-13 50.4 6.4 9.2e-12 44.8 6.4 2.1 1 1 0 1 1 1 1 UbiA prenyltransferase family Mito_carr PF00153.27 KIK40691.1 - 1.3e-56 188.5 0.2 9.2e-21 73.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 KIK40692.1 - 1.7e-27 96.3 27.4 2.5e-27 95.8 26.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIK40692.1 - 2.3e-05 23.9 17.9 0.00015 21.2 4.6 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB PepSY_2 PF13670.6 KIK40692.1 - 0.021 14.8 0.3 0.047 13.7 0.3 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain UbiA PF01040.18 KIK40695.1 - 3.4e-12 46.2 8.1 4.3e-10 39.3 1.5 2.1 2 0 0 2 2 2 2 UbiA prenyltransferase family ABC_membrane_2 PF06472.15 KIK40698.1 - 3e-77 259.7 0.5 4.8e-77 259.0 0.5 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KIK40698.1 - 6.4e-15 55.9 0.0 1.1e-14 55.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.12 KIK40698.1 - 0.051 13.5 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 NACHT domain Latarcin PF10279.9 KIK40698.1 - 0.11 13.0 0.0 0.26 11.7 0.0 1.8 2 0 0 2 2 2 0 Latarcin precursor Mg_chelatase PF01078.21 KIK40698.1 - 0.11 11.9 0.4 0.22 10.9 0.4 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI HTH_Tnp_IS1 PF12759.7 KIK40698.1 - 0.2 11.3 0.7 16 5.2 0.1 3.0 3 0 0 3 3 3 0 InsA C-terminal domain ExoD PF06055.12 KIK40699.1 - 0.00016 21.1 0.3 0.00016 21.1 0.3 2.0 1 1 0 2 2 2 1 Exopolysaccharide synthesis, ExoD CBS PF00571.28 KIK40700.1 - 5.8e-07 29.9 0.0 0.0013 19.2 0.0 2.4 2 1 0 2 2 2 2 CBS domain Mlh1_C PF16413.5 KIK40702.1 - 1.6e-86 290.1 0.2 2.7e-86 289.3 0.2 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KIK40702.1 - 3.8e-30 104.0 0.1 7.8e-30 103.0 0.1 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KIK40702.1 - 2.1e-12 47.0 0.0 5.5e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KIK40702.1 - 9.7e-09 35.7 0.0 3.7e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BioT2 PF15368.6 KIK40702.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Spermatogenesis family BioT2 MOR2-PAG1_N PF14222.6 KIK40703.1 - 9.1e-163 543.1 0.0 2.2e-162 541.8 0.0 1.7 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KIK40703.1 - 3.3e-73 246.7 1.2 8.3e-73 245.4 0.2 2.3 2 0 0 2 2 2 1 Cell morphogenesis C-terminal Putative_PNPOx PF01243.20 KIK40704.1 - 9.8e-06 25.7 0.0 1.9e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 KIK40705.1 - 3.6e-06 27.1 0.0 7.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase MtrF PF09472.10 KIK40705.1 - 0.14 11.6 0.2 0.26 10.7 0.2 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Transp_cyt_pur PF02133.15 KIK40706.1 - 2.8e-97 326.3 38.9 3.5e-97 326.0 38.9 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin zf-C3HC4_3 PF13920.6 KIK40707.1 - 4.8e-05 23.1 3.3 7.3e-05 22.5 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK40707.1 - 0.00067 19.5 5.1 0.0014 18.5 5.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KIK40707.1 - 0.00092 19.1 4.7 0.0018 18.2 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain RRM_1 PF00076.22 KIK40707.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.25 KIK40707.1 - 0.0016 18.3 4.2 0.0032 17.3 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Siva PF05458.12 KIK40707.1 - 0.04 13.6 3.5 0.075 12.7 3.5 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-RING_2 PF13639.6 KIK40707.1 - 0.13 12.7 4.4 0.25 11.7 4.4 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KIK40707.1 - 1.1 9.1 5.4 4.4 7.2 5.6 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) F-box-like PF12937.7 KIK40711.1 - 0.00068 19.5 3.7 0.00094 19.0 0.5 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK40711.1 - 0.0068 16.3 2.9 0.008 16.0 0.1 2.6 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.7 KIK40711.1 - 1.3 9.6 5.0 21 5.7 0.0 3.3 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Ribosomal_S26e PF01283.19 KIK40713.1 - 2.2e-53 179.2 8.2 2.6e-53 179.0 8.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KIK40713.1 - 0.0082 16.1 0.1 0.014 15.3 0.1 1.4 1 0 0 1 1 1 1 Zinc binding domain zf-PARP PF00645.18 KIK40714.1 - 1.7e-24 86.4 0.1 1.7e-24 86.4 0.1 2.4 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region TPR_2 PF07719.17 KIK40717.1 - 0.0019 18.1 0.2 19 5.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF3856 PF12968.7 KIK40717.1 - 0.017 15.2 0.1 9.2 6.3 0.0 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_1 PF00515.28 KIK40717.1 - 0.081 12.8 0.2 21 5.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.32 KIK40720.1 - 4.2e-36 122.3 17.3 5e-07 30.3 0.2 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40720.1 - 7.3e-12 45.4 0.3 0.28 11.5 0.0 5.7 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 KIK40720.1 - 5.9e-10 39.7 2.5 1.9e-07 31.5 0.2 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) eIF2A PF08662.11 KIK40720.1 - 4.2e-06 26.8 0.1 0.18 11.7 0.1 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK40720.1 - 0.00034 19.7 0.2 0.039 12.9 0.0 3.3 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_14 PF13428.6 KIK40720.1 - 0.002 18.8 5.1 7.5 7.7 0.2 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK40720.1 - 0.0089 16.1 11.1 11 6.4 0.2 6.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK40720.1 - 0.14 12.0 10.0 1.4 8.9 0.3 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK40720.1 - 0.38 11.3 7.3 7.9 7.1 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK40720.1 - 3.8 8.2 9.0 20 5.9 0.2 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat F-box-like PF12937.7 KIK40722.1 - 0.00046 20.0 0.0 0.00046 20.0 0.0 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIK40722.1 - 0.0014 18.4 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain CxC4 PF18717.1 KIK40722.1 - 0.9 9.4 4.8 2.2 8.1 0.1 3.0 3 0 0 3 3 3 0 CxC4 like cysteine cluster associated with KDZ transposases Zn_ribbon_SprT PF17283.2 KIK40722.1 - 0.95 9.4 5.2 1.1 9.2 0.2 3.1 3 0 0 3 3 3 0 SprT-like zinc ribbon domain PHC2_SAM_assoc PF16616.5 KIK40722.1 - 2.2 9.1 5.7 5.6 7.8 2.8 2.4 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 RNHCP PF12647.7 KIK40722.1 - 4.4 7.4 11.0 26 4.9 0.1 3.6 3 0 0 3 3 3 0 RNHCP domain ATG13 PF10033.9 KIK40723.1 - 0.04 13.6 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 13 ATP_transf PF09830.9 KIK40724.1 - 2.9e-20 72.2 0.2 5e-20 71.4 0.2 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4922 PF16269.5 KIK40724.1 - 0.036 13.8 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4922) HIT PF01230.23 KIK40724.1 - 0.078 13.7 0.4 0.95 10.2 0.1 2.4 2 0 0 2 2 2 0 HIT domain SLATT_3 PF18184.1 KIK40726.1 - 0.074 13.2 0.3 0.12 12.5 0.3 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 HicA_toxin PF07927.12 KIK40727.1 - 3.5e-06 27.0 0.0 9.5e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, LZ_Tnp_IS66 PF13007.7 KIK40727.1 - 0.3 11.9 6.4 0.19 12.5 2.9 2.6 1 1 1 2 2 2 0 Transposase C of IS166 homeodomain zf-MYND PF01753.18 KIK40728.1 - 1.7e-10 40.8 12.2 2.7e-10 40.1 12.2 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIK40728.1 - 0.21 11.9 6.5 0.45 10.9 6.5 1.7 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding RabGAP-TBC PF00566.18 KIK40729.1 - 4.3e-51 173.6 0.0 5.6e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IL34 PF15036.6 KIK40729.1 - 0.019 15.0 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 Interleukin 34 NUP50 PF08911.11 KIK40730.1 - 1.3e-16 61.0 0.1 1.3e-16 61.0 0.1 5.9 5 1 0 5 5 5 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 KIK40730.1 - 1.4e-15 57.6 0.1 3.2e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 RanBP1 domain HsbA PF12296.8 KIK40730.1 - 0.054 13.9 2.6 0.14 12.6 2.6 1.7 1 0 0 1 1 1 0 Hydrophobic surface binding protein A TIG PF01833.24 KIK40731.1 - 3.4e-11 43.0 1.1 3.4e-10 39.9 0.1 3.1 3 0 0 3 3 3 1 IPT/TIG domain Ank_5 PF13857.6 KIK40731.1 - 3.3e-10 40.0 1.2 5.8e-06 26.5 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK40731.1 - 1e-09 38.8 0.0 2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIK40731.1 - 1.9e-09 37.5 0.5 0.0021 18.4 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KIK40731.1 - 6e-09 36.3 0.2 3.1e-08 34.0 0.2 2.3 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK40731.1 - 5.9e-07 29.3 0.2 0.019 15.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat RraA-like PF03737.15 KIK40732.1 - 1.6e-37 128.9 0.1 2.1e-37 128.6 0.1 1.1 1 0 0 1 1 1 1 Aldolase/RraA Methyltransf_25 PF13649.6 KIK40734.1 - 0.0084 16.8 0.0 0.027 15.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK40734.1 - 0.076 13.7 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain VanZ PF04892.12 KIK40737.1 - 0.00024 21.8 4.9 0.00047 20.8 4.9 1.5 1 1 0 1 1 1 1 VanZ like family DUF1275 PF06912.11 KIK40737.1 - 0.95 9.4 4.5 9.8 6.0 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1275) MnmE_helical PF12631.7 KIK40738.1 - 0.092 12.9 0.8 10 6.2 0.0 2.8 3 1 0 3 3 3 0 MnmE helical domain IMS PF00817.20 KIK40739.1 - 2.1e-42 144.6 0.0 4e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KIK40739.1 - 1.2e-14 55.0 0.1 4.3e-14 53.2 0.1 1.9 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KIK40739.1 - 4.4e-07 29.9 0.0 9.6e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif RNF220 PF15926.5 KIK40739.1 - 0.042 13.5 0.2 0.087 12.4 0.2 1.4 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 Peptidase_C14 PF00656.22 KIK40740.1 - 1.3e-19 71.1 0.0 2.2e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Caspase domain APG6 PF04111.12 KIK40741.1 - 2.6e-71 239.3 0.0 4.5e-71 238.5 0.0 1.4 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KIK40741.1 - 1.7e-29 103.0 22.6 1.7e-29 103.0 22.6 1.6 2 0 0 2 2 2 1 Apg6 coiled-coil region zf-P11 PF03854.14 KIK40741.1 - 0.097 12.3 0.9 0.71 9.6 0.1 2.3 2 0 0 2 2 2 0 P-11 zinc finger HTH_57 PF18679.1 KIK40741.1 - 0.19 12.1 2.5 0.22 11.9 0.9 1.9 2 1 0 2 2 2 0 ThcOx helix turn helix domain GCS PF03074.16 KIK40742.1 - 9.5e-172 571.4 0.0 1.2e-171 571.1 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 KIK40742.1 - 0.039 13.3 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) ATP-synt_DE_N PF02823.16 KIK40743.1 - 1.3e-15 57.0 0.1 2e-15 56.4 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 2OG-FeII_Oxy_2 PF13532.6 KIK40744.1 - 6.3e-21 75.5 0.0 1.2e-20 74.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FACT-Spt16_Nlob PF14826.6 KIK40745.1 - 3.4e-41 140.7 0.0 4.2e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain DUF572 PF04502.13 KIK40746.1 - 3.7e-83 279.9 1.7 4.2e-83 279.7 1.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.14 KIK40746.1 - 0.015 15.2 0.7 0.66 10.0 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif eIF3_subunit PF08597.10 KIK40746.1 - 0.23 11.3 10.2 0.35 10.8 10.2 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Metallophos PF00149.28 KIK40747.1 - 3.2e-14 53.9 0.1 6.5e-14 52.9 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIK40747.1 - 2.1e-05 24.8 0.0 0.00019 21.6 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RNA_pol_Rpc82 PF05645.13 KIK40748.1 - 1.2e-17 64.6 4.7 5.6e-15 55.8 1.6 3.8 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KIK40748.1 - 4.5e-17 61.9 1.0 4.6e-11 42.6 0.2 3.8 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KIK40748.1 - 3.8e-10 39.6 0.0 1e-05 25.3 0.0 4.4 4 0 0 4 4 4 3 TFIIE alpha subunit IATP PF04568.12 KIK40749.1 - 1.1e-06 29.0 0.2 1.3e-06 28.7 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP ATP_sub_h PF10775.9 KIK40750.1 - 1.2e-25 89.3 0.7 1.7e-25 88.8 0.7 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h DUF2420 PF10336.9 KIK40751.1 - 4.9e-07 29.7 0.0 1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) DUF4574 PF15141.6 KIK40752.1 - 0.86 9.6 2.7 2.8 7.9 0.6 2.5 2 1 1 3 3 3 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 NAD_binding_7 PF13241.6 KIK40753.1 - 2.2e-28 98.7 0.0 8.2e-28 96.9 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KIK40753.1 - 7.6e-22 76.7 0.2 1.1e-21 76.2 0.2 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KIK40753.1 - 3.4e-15 55.2 0.2 3.4e-15 55.2 0.2 1.7 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central TrkA_N PF02254.18 KIK40753.1 - 0.015 15.5 0.1 0.024 14.9 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain AdoHcyase_NAD PF00670.21 KIK40753.1 - 0.062 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Tetraspanin PF00335.20 KIK40754.1 - 0.86 9.3 16.4 3 7.5 16.4 2.3 1 1 0 1 1 1 0 Tetraspanin family Bmt2 PF11968.8 KIK40755.1 - 1.5e-62 211.3 0.0 1.9e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 KIK40755.1 - 2e-05 24.5 0.0 5e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK40755.1 - 0.19 12.5 0.0 0.79 10.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Pkinase_fungal PF17667.1 KIK40757.1 - 3.1e-14 52.6 0.2 3.4e-14 52.5 0.2 1.0 1 0 0 1 1 1 1 Fungal protein kinase RHSP PF07999.11 KIK40757.1 - 0.067 12.0 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Retrotransposon hot spot protein MBF1 PF08523.10 KIK40759.1 - 1.9e-20 73.1 0.5 1.9e-20 73.1 0.5 1.8 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KIK40759.1 - 5.3e-13 48.8 0.2 7.8e-13 48.3 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KIK40759.1 - 1e-05 25.7 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KIK40759.1 - 2.5e-05 24.2 0.1 3.9e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KIK40759.1 - 0.0086 15.9 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 KIK40759.1 - 0.011 15.7 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_26 PF13443.6 KIK40759.1 - 0.06 13.8 0.0 0.094 13.2 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Tubulin PF00091.25 KIK40760.1 - 4.2e-71 239.2 0.0 2.1e-70 237.0 0.0 1.9 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KIK40760.1 - 6.1e-47 158.9 0.4 1.3e-46 157.8 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KIK40760.1 - 0.00024 21.4 0.0 0.001 19.4 0.0 2.0 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KIK40760.1 - 0.0004 20.1 0.0 0.00072 19.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Hrs_helical PF12210.8 KIK40760.1 - 0.099 13.2 0.5 0.24 11.9 0.5 1.6 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Tubulin_2 PF13809.6 KIK40760.1 - 0.15 11.2 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Tubulin like RNA12 PF10443.9 KIK40761.1 - 1e-102 344.2 0.0 1.7e-62 211.7 0.0 2.2 1 1 1 2 2 2 2 RNA12 protein AAA_16 PF13191.6 KIK40761.1 - 5.1e-05 23.7 0.3 0.00016 22.1 0.3 1.9 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK40761.1 - 0.0029 17.6 0.0 0.01 15.7 0.0 2.0 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK40761.1 - 0.014 15.7 0.1 0.081 13.2 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KIK40761.1 - 0.015 15.7 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CENP-F_leu_zip PF10473.9 KIK40761.1 - 0.05 13.6 3.5 0.17 11.9 3.5 1.9 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_29 PF13555.6 KIK40761.1 - 0.056 13.2 0.3 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain RRM_1 PF00076.22 KIK40761.1 - 0.093 12.6 0.0 0.8 9.6 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMC_N PF02463.19 KIK40761.1 - 0.15 11.4 0.1 0.55 9.6 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Mago_nashi PF02792.14 KIK40762.1 - 4.6e-74 247.2 0.2 5.1e-74 247.1 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein Ribosomal_S10 PF00338.22 KIK40763.1 - 1.1e-27 96.1 0.0 1.7e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF974 PF06159.13 KIK40764.1 - 7.5e-75 251.9 0.0 1e-74 251.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Nop14 PF04147.12 KIK40765.1 - 1.5e-288 959.9 5.8 1.7e-288 959.6 5.8 1.0 1 0 0 1 1 1 1 Nop14-like family V-ATPase_H_N PF03224.14 KIK40766.1 - 8.9e-86 288.0 3.3 1.1e-85 287.7 3.3 1.1 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KIK40766.1 - 1.2e-42 144.7 0.0 1.8e-41 140.9 0.0 2.7 3 0 0 3 3 3 1 V-ATPase subunit H HEAT PF02985.22 KIK40766.1 - 8.6e-07 28.7 0.3 0.14 12.4 0.0 4.9 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 KIK40766.1 - 0.00031 21.1 0.8 0.052 13.9 0.0 3.9 3 2 1 4 4 4 2 HEAT repeats Arm_2 PF04826.13 KIK40766.1 - 0.009 15.5 0.0 0.062 12.8 0.0 2.1 2 0 0 2 2 2 1 Armadillo-like Adaptin_N PF01602.20 KIK40766.1 - 0.036 12.6 2.3 0.2 10.2 0.6 2.7 2 1 0 2 2 2 0 Adaptin N terminal region RTP1_C1 PF10363.9 KIK40766.1 - 0.039 14.1 1.3 3.5 7.8 0.1 3.4 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KIK40766.1 - 0.064 13.3 3.6 14 5.9 0.0 4.9 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF1981 PF09324.10 KIK40766.1 - 0.23 11.3 1.0 0.64 9.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) MRP-L46 PF11788.8 KIK40767.1 - 3.3e-19 69.8 1.0 4.4e-19 69.4 0.2 1.7 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KIK40767.1 - 6e-07 29.6 0.0 1.5e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Endonuclease_NS PF01223.23 KIK40768.1 - 5.3e-57 193.2 0.0 6.6e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease R3H PF01424.22 KIK40769.1 - 2.3e-10 40.3 0.1 2.3e-10 40.3 0.1 2.6 3 0 0 3 3 3 1 R3H domain RRM_1 PF00076.22 KIK40769.1 - 4.7e-08 32.7 0.0 1.6e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.26 KIK40771.1 - 9.6e-45 151.7 0.0 1.1e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KIK40771.1 - 0.00017 21.9 0.0 0.0002 21.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KIK40771.1 - 0.00049 19.8 0.0 0.00061 19.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KIK40771.1 - 0.065 13.1 0.1 0.13 12.2 0.1 1.5 1 1 0 1 1 1 0 UEV domain EF-hand_4 PF12763.7 KIK40772.1 - 1.6e-36 124.4 0.0 2.7e-14 53.0 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KIK40772.1 - 1.5e-08 34.9 0.0 0.00015 22.1 0.0 3.9 3 0 0 3 3 3 1 EF-hand domain pair UBA PF00627.31 KIK40772.1 - 7.8e-07 28.9 0.0 1.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.32 KIK40772.1 - 0.0009 18.6 5.9 1.1 9.0 0.1 4.3 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 KIK40772.1 - 0.005 16.7 4.3 7.1 6.8 0.0 4.6 5 0 0 5 5 5 2 EF-hand domain UBA_4 PF14555.6 KIK40772.1 - 0.017 14.9 0.0 0.046 13.5 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain Bcr-Abl_Oligo PF09036.10 KIK40772.1 - 0.57 10.2 2.4 0.62 10.1 0.1 2.2 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF745 PF05335.13 KIK40772.1 - 1.9 8.2 24.7 0.14 11.9 9.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF745) CALCOCO1 PF07888.11 KIK40772.1 - 2.1 7.1 31.5 0.31 9.8 18.7 2.4 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like WEMBL PF05701.11 KIK40772.1 - 2.8 6.5 31.8 8 5.0 31.8 1.6 1 1 0 1 1 1 0 Weak chloroplast movement under blue light PDEase_II PF02112.15 KIK40773.1 - 1.7e-36 126.0 0.0 2.8e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 KIK40773.1 - 2e-06 27.5 0.0 3.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain WD40 PF00400.32 KIK40774.1 - 4.5e-17 62.1 0.5 8e-07 29.7 1.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40774.1 - 2.1e-08 34.4 0.0 0.012 15.9 0.0 3.3 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KIK40774.1 - 0.0018 17.9 0.0 0.0022 17.6 0.0 1.1 1 0 0 1 1 1 1 PQQ-like domain Nup160 PF11715.8 KIK40774.1 - 0.046 12.4 0.0 0.51 8.9 0.0 2.3 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Asp PF00026.23 KIK40777.1 - 1.7e-39 136.1 13.6 6.6e-39 134.2 13.2 2.1 2 1 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK40777.1 - 1.9e-06 28.3 4.1 0.0025 18.1 0.1 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal RTT107_BRCT_5 PF16770.5 KIK40778.1 - 0.011 15.7 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain CAP59_mtransfer PF11735.8 KIK40779.1 - 6.3e-38 130.8 0.1 1e-37 130.1 0.1 1.4 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Abhydro_lipase PF04083.16 KIK40780.1 - 0.049 13.2 0.0 0.087 12.4 0.0 1.4 1 1 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region 7TM_GPCR_Srab PF10292.9 KIK40782.1 - 0.18 10.7 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor zf-C3HC4_2 PF13923.6 KIK40784.1 - 0.046 13.6 0.0 0.046 13.6 0.0 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FAD_binding_4 PF01565.23 KIK40786.1 - 4.3e-09 36.2 0.1 0.0034 17.1 0.1 2.5 2 0 0 2 2 2 2 FAD binding domain BBE PF08031.12 KIK40786.1 - 9.8e-09 35.2 0.0 2.1e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like ALO PF04030.14 KIK40786.1 - 0.023 14.5 0.1 0.038 13.8 0.1 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase DEC-1_N PF04625.13 KIK40786.1 - 0.19 10.7 2.8 0.36 9.8 2.8 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region p450 PF00067.22 KIK40787.1 - 4.2e-76 256.6 0.0 2.3e-75 254.1 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Uso1_p115_head PF04869.14 KIK40788.1 - 7.8e-44 150.1 0.0 2.8e-42 145.0 0.0 2.8 2 1 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KIK40788.1 - 1.2e-06 28.9 15.5 2.4e-06 28.0 15.5 1.4 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region HEAT_2 PF13646.6 KIK40788.1 - 0.002 18.5 2.7 0.68 10.4 0.0 3.2 2 1 1 3 3 3 2 HEAT repeats Arm_vescicular PF18770.1 KIK40788.1 - 0.015 15.2 0.1 0.053 13.4 0.1 1.9 1 0 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor COMP PF11598.8 KIK40788.1 - 0.021 15.3 0.2 0.053 14.0 0.2 1.6 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein MMS19_N PF14500.6 KIK40788.1 - 0.024 14.2 0.1 0.042 13.4 0.1 1.5 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF3450 PF11932.8 KIK40788.1 - 0.045 13.0 1.9 0.076 12.3 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HEAT PF02985.22 KIK40788.1 - 0.24 11.8 1.5 37 5.0 0.0 4.4 3 0 0 3 3 3 0 HEAT repeat SlyX PF04102.12 KIK40788.1 - 0.36 11.5 3.6 0.38 11.4 1.5 2.2 1 1 1 2 2 2 0 SlyX Sacchrp_dh_C PF16653.5 KIK40789.1 - 4.1e-73 246.8 0.0 5.7e-73 246.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KIK40789.1 - 1.8e-21 76.7 0.1 3.3e-21 75.9 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_N PF05222.15 KIK40789.1 - 2e-10 41.1 0.0 1.3e-09 38.4 0.0 2.3 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain Shikimate_DH PF01488.20 KIK40789.1 - 6.8e-06 26.2 0.1 1.4e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KIK40789.1 - 2.1e-05 23.9 0.0 0.18 11.1 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.6 KIK40789.1 - 0.00037 20.4 0.1 0.00071 19.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding IlvN PF07991.12 KIK40789.1 - 0.002 17.8 0.0 0.0041 16.7 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 KIK40789.1 - 0.0029 17.0 0.0 0.0084 15.5 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KIK40789.1 - 0.097 13.5 0.1 0.2 12.5 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 KIK40789.1 - 0.11 13.1 0.2 0.7 10.5 0.1 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF21 PF01595.20 KIK40790.1 - 1.2e-34 119.5 0.2 1.9e-34 118.9 0.2 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KIK40790.1 - 0.0029 18.0 0.9 14 6.2 0.1 3.7 3 0 0 3 3 3 2 CBS domain Abhydrolase_6 PF12697.7 KIK40791.1 - 6.2e-12 46.6 0.0 7e-12 46.4 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK40791.1 - 2e-10 40.8 0.0 2.6e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK40791.1 - 1.4e-07 31.0 0.0 1.9e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KIK40791.1 - 2.7e-05 23.2 0.0 4.8e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KIK40791.1 - 5.4e-05 22.3 0.0 0.00016 20.8 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase PGAP1 PF07819.13 KIK40791.1 - 0.01 15.6 0.1 0.1 12.3 0.1 2.0 1 1 1 2 2 2 0 PGAP1-like protein PAF-AH_p_II PF03403.13 KIK40791.1 - 0.1 11.1 0.0 0.16 10.4 0.0 1.4 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Lipase_3 PF01764.25 KIK40791.1 - 0.16 11.9 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.18 KIK40791.1 - 0.17 11.4 0.0 0.62 9.6 0.0 1.8 1 1 1 2 2 2 0 Dienelactone hydrolase family FSH1 PF03959.13 KIK40791.1 - 0.19 11.4 0.0 0.37 10.4 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DDE_3 PF13358.6 KIK40793.1 - 0.00018 21.3 0.1 0.00049 19.9 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF4413 PF14372.6 KIK40797.1 - 0.0085 16.4 1.3 0.0091 16.3 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) PRMT5 PF05185.16 KIK40797.1 - 0.052 13.4 0.8 0.06 13.2 0.8 1.1 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Dynactin_p22 PF07426.11 KIK40801.1 - 0.071 13.0 0.0 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Dynactin subunit p22 DDE_1 PF03184.19 KIK40802.1 - 1.4e-18 67.2 0.1 1.5e-18 67.1 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease RNA_pol_Rpb2_5 PF04567.17 KIK40802.1 - 0.087 13.4 0.1 0.35 11.5 0.1 1.9 1 1 0 1 1 1 0 RNA polymerase Rpb2, domain 5 DDE_1 PF03184.19 KIK40803.1 - 1.7e-13 50.6 0.0 3.7e-13 49.5 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KIK40804.1 - 1.5e-05 25.0 0.1 3.1e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Arg_repressor PF01316.21 KIK40804.1 - 0.0033 17.1 0.0 0.0071 16.1 0.0 1.6 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain RasGEF_N PF00618.20 KIK40806.1 - 1.9e-13 50.6 0.1 7.9e-13 48.6 0.0 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif RasGEF PF00617.19 KIK40806.1 - 8.4e-13 48.9 0.0 2.5e-12 47.4 0.0 1.9 1 0 0 1 1 1 1 RasGEF domain Smg4_UPF3 PF03467.15 KIK40808.1 - 8.9e-53 178.9 1.1 8.9e-53 178.9 1.1 2.3 2 0 0 2 2 2 1 Smg-4/UPF3 family DUF4121 PF13497.6 KIK40808.1 - 0.048 12.8 0.0 0.073 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) HGTP_anticodon2 PF12745.7 KIK40808.1 - 6.6 6.2 6.9 13 5.1 6.9 1.4 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs GPI-anchored PF10342.9 KIK40809.1 - 1.3e-08 35.4 2.5 1.6e-08 35.2 2.5 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ORC_WH_C PF18137.1 KIK40810.1 - 1.3e-37 129.0 0.0 2.2e-37 128.2 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 KIK40810.1 - 3.9e-30 105.1 0.0 1.1e-29 103.7 0.0 1.7 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus DUF4351 PF14261.6 KIK40810.1 - 0.17 12.0 0.0 0.69 10.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) MCM PF00493.23 KIK40811.1 - 1.9e-96 321.5 0.0 3e-96 320.8 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KIK40811.1 - 1.7e-38 131.3 0.6 1.7e-38 131.3 0.6 1.7 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 KIK40811.1 - 1.7e-27 95.7 1.8 3.1e-27 94.8 1.8 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KIK40811.1 - 9.9e-16 58.2 0.1 3.8e-15 56.4 0.1 2.1 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 KIK40811.1 - 1.7e-08 34.6 0.0 5.6e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KIK40811.1 - 6.8e-08 32.1 0.0 5.4e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KIK40811.1 - 1.3e-05 25.1 0.0 0.00032 20.6 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KIK40811.1 - 0.00022 21.0 0.9 0.88 9.3 0.0 4.1 5 0 0 5 5 5 2 Sigma-54 interaction domain AAA_16 PF13191.6 KIK40811.1 - 0.0051 17.2 0.1 0.039 14.3 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK40811.1 - 0.16 12.4 0.0 0.43 11.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SYF2 PF08231.12 KIK40812.1 - 3.2e-62 209.6 6.3 3.2e-62 209.6 6.3 1.9 2 0 0 2 2 2 1 SYF2 splicing factor MIase PF02426.16 KIK40816.1 - 0.0096 16.1 0.7 4.2 7.6 0.1 2.8 2 0 0 2 2 2 2 Muconolactone delta-isomerase PsbH PF00737.20 KIK40816.1 - 0.016 15.0 1.5 28 4.6 0.0 3.2 3 0 0 3 3 3 0 Photosystem II 10 kDa phosphoprotein DUF489 PF04356.12 KIK40816.1 - 0.025 14.6 0.7 0.036 14.1 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) USP8_interact PF08941.10 KIK40816.1 - 6 6.6 7.4 22 4.8 2.1 3.4 4 0 0 4 4 4 0 USP8 interacting MoCF_biosynth PF00994.24 KIK40817.1 - 2.5e-31 108.3 0.0 3.8e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain bcl-2I13 PF12201.8 KIK40817.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Bcl2-interacting killer, BH3-domain containing Pyr_redox_2 PF07992.14 KIK40819.1 - 1.5e-47 162.3 0.0 1.8e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK40819.1 - 3.8e-10 40.2 0.0 5.4e-08 33.3 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK40819.1 - 0.013 14.7 0.0 14 4.8 0.0 3.6 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase WH1 PF00568.23 KIK40820.1 - 3.5e-13 49.5 0.2 6.4e-12 45.4 0.2 2.1 2 0 0 2 2 2 1 WH1 domain DCP1 PF06058.13 KIK40820.1 - 0.019 14.9 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Dcp1-like decapping family GST_C_6 PF17171.4 KIK40822.1 - 0.19 11.5 1.3 4.1 7.3 0.2 2.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF4799 PF16056.5 KIK40824.1 - 0.0042 16.3 0.8 0.0065 15.7 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4799) DAO PF01266.24 KIK40825.1 - 3.9e-55 187.9 0.8 5.5e-55 187.4 0.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIK40825.1 - 0.00073 20.0 0.5 0.021 15.3 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK40825.1 - 0.0014 17.9 0.1 0.027 13.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK40825.1 - 0.0019 18.4 0.2 0.0053 17.0 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.19 KIK40825.1 - 0.0033 16.9 0.2 2.5 7.4 0.1 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Sacchrp_dh_NADP PF03435.18 KIK40825.1 - 0.012 15.9 0.2 0.078 13.2 0.1 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 KIK40825.1 - 0.044 13.0 0.3 0.089 12.0 0.3 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KIK40825.1 - 0.05 13.6 1.1 0.69 9.9 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KIK40825.1 - 0.052 12.6 0.6 1.6 7.7 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 KIK40825.1 - 0.057 12.5 0.1 3.9 6.4 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KIK40825.1 - 0.075 11.9 0.9 0.37 9.6 0.9 1.8 1 1 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 KIK40825.1 - 0.12 11.6 0.0 2.3 7.4 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain MMTV_SAg PF01054.17 KIK40829.1 - 0.06 12.9 0.0 0.086 12.4 0.0 1.3 1 1 0 1 1 1 0 Mouse mammary tumour virus superantigen Chromo PF00385.24 KIK40833.1 - 2e-17 62.8 4.7 8.5e-13 48.0 1.3 2.1 1 1 1 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain XPG_I_2 PF12813.7 KIK40833.1 - 0.099 12.1 0.8 0.11 11.9 0.8 1.1 1 0 0 1 1 1 0 XPG domain containing Inhibitor_I36 PF03995.13 KIK40833.1 - 0.23 11.4 5.2 17 5.4 5.1 2.3 1 1 0 1 1 1 0 Peptidase inhibitor family I36 WD40 PF00400.32 KIK40838.1 - 2.1e-18 66.3 2.7 1.1e-09 38.8 0.0 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40838.1 - 1.9e-05 24.9 0.0 0.0056 17.0 0.0 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK40838.1 - 0.0031 16.2 0.0 0.015 14.0 0.0 1.8 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KIK40838.1 - 0.022 13.5 0.0 0.035 12.9 0.0 1.4 1 1 0 1 1 1 0 Nup133 N terminal like Cytochrom_D1 PF02239.16 KIK40838.1 - 0.042 12.4 0.0 0.052 12.1 0.0 1.0 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF3638 PF12340.8 KIK40839.1 - 2.1e-89 298.7 3.1 4.4e-89 297.7 3.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KIK40839.1 - 3.3e-15 55.2 0.1 3.3e-15 55.2 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3645) T4SS PF07996.11 KIK40839.1 - 0.067 13.6 0.3 0.21 12.0 0.3 1.8 1 0 0 1 1 1 0 Type IV secretion system proteins TFR_dimer PF04253.15 KIK40841.1 - 6.1e-21 74.8 0.2 5.5e-19 68.4 0.0 2.9 3 0 0 3 3 3 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KIK40841.1 - 1.1e-17 64.4 0.0 1e-16 61.2 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KIK40841.1 - 9.1e-12 44.8 0.6 2.3e-11 43.5 0.6 1.8 1 1 0 1 1 1 1 PA domain TPR_2 PF07719.17 KIK40843.1 - 5.7e-06 26.0 0.1 2.4 8.5 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK40843.1 - 0.0099 16.6 0.2 0.51 11.3 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Peripla_BP_5 PF13433.6 KIK40843.1 - 0.064 12.2 0.0 0.084 11.8 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein domain HET PF06985.11 KIK40844.1 - 3.3e-12 47.0 1.8 6.4e-11 42.8 0.1 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) WD40 PF00400.32 KIK40845.1 - 1.4e-37 127.0 16.1 8.6e-06 26.4 0.2 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40845.1 - 1.7e-16 60.3 0.3 0.0006 20.1 0.0 6.7 3 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK40845.1 - 0.0019 17.2 0.1 0.063 12.2 0.0 2.6 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 KIK40845.1 - 0.0022 18.4 1.2 0.43 11.1 0.1 3.8 3 2 0 3 3 3 1 PQQ-like domain Nup160 PF11715.8 KIK40845.1 - 0.0072 15.0 4.3 1.3 7.5 0.6 3.9 2 2 1 4 4 4 1 Nucleoporin Nup120/160 SUIM_assoc PF16619.5 KIK40845.1 - 0.046 13.8 4.0 0.085 12.9 4.0 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CCDC24 PF15669.5 KIK40845.1 - 0.093 12.6 2.4 0.15 11.9 2.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family WD40 PF00400.32 KIK40846.1 - 1.9e-41 139.3 24.4 5e-07 30.3 0.5 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40846.1 - 1.2e-17 64.0 2.5 0.00026 21.2 0.0 5.6 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK40846.1 - 4e-05 22.5 1.6 0.22 10.1 0.0 3.9 2 2 2 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK40846.1 - 0.00035 20.5 0.2 1.6 8.6 0.0 3.3 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KIK40846.1 - 0.0034 16.8 0.1 0.045 13.1 0.0 2.7 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KIK40846.1 - 0.0043 17.0 0.0 17 5.5 0.0 4.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK40846.1 - 0.0075 15.3 0.0 8.8 5.2 0.0 3.8 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PHTB1_N PF14727.6 KIK40846.1 - 0.078 12.3 0.0 0.16 11.3 0.0 1.4 2 0 0 2 2 2 0 PTHB1 N-terminus Kelch_6 PF13964.6 KIK40846.1 - 0.091 13.1 0.6 6.3 7.2 0.0 3.6 5 0 0 5 5 5 0 Kelch motif RPAP1_C PF08620.10 KIK40850.1 - 6.7e-19 67.8 0.1 1.5e-18 66.6 0.1 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KIK40850.1 - 1.7e-09 37.3 2.4 4.9e-09 35.8 2.4 1.8 1 0 0 1 1 1 1 RPAP1-like, N-terminal DUF3526 PF12040.8 KIK40850.1 - 2 8.9 3.7 1.4 9.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3526) DIOX_N PF14226.6 KIK40851.1 - 1.7e-20 74.0 0.0 1.9e-20 73.8 0.0 1.0 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal UIM PF02809.20 KIK40851.1 - 0.098 12.6 1.0 0.22 11.5 1.0 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif 2OG-FeII_Oxy PF03171.20 KIK40853.1 - 1.2e-18 67.4 0.0 1.8e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KIK40854.1 - 5.5e-33 114.2 0.0 8.1e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK40854.1 - 5.8e-17 62.0 0.0 1.4e-16 60.8 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Methyltransf_25 PF13649.6 KIK40855.1 - 1.1e-12 48.5 0.0 6.4e-12 46.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KIK40855.1 - 4.9e-11 42.6 1.2 1.1e-10 41.4 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KIK40855.1 - 5e-11 43.1 0.0 6.9e-10 39.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK40855.1 - 1.1e-10 41.5 0.0 2.6e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK40855.1 - 1.9e-10 40.9 0.1 8.3e-09 35.5 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK40855.1 - 1.5e-06 28.8 0.7 1.4e-05 25.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KIK40855.1 - 5.6e-06 26.0 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 KIK40855.1 - 6e-05 23.0 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KIK40855.1 - 0.0017 18.1 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_24 PF13578.6 KIK40855.1 - 0.0018 19.3 0.0 0.0059 17.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KIK40855.1 - 0.0063 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_9 PF08003.11 KIK40855.1 - 0.011 14.7 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.15 KIK40855.1 - 0.014 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 FmrO PF07091.11 KIK40855.1 - 0.017 14.7 0.1 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) PCMT PF01135.19 KIK40855.1 - 0.022 14.5 0.1 0.036 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 KIK40855.1 - 0.043 13.2 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB CMAS PF02353.20 KIK40855.1 - 0.09 12.0 0.7 0.12 11.6 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 KIK40855.1 - 0.095 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NFACT-R_1 PF05670.13 KIK40856.1 - 3e-40 137.2 0.2 5.3e-40 136.5 0.0 1.5 2 0 0 2 2 2 1 NFACT protein RNA binding domain RRM_1 PF00076.22 KIK40857.1 - 2e-09 37.1 0.0 7.4e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 KIK40857.1 - 2.3e-07 31.0 1.4 4.3e-07 30.1 0.1 2.0 2 0 0 2 2 2 1 PWI domain DUF494 PF04361.13 KIK40857.1 - 0.0095 15.8 1.0 0.026 14.4 1.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF494) Trehalase PF01204.18 KIK40858.1 - 6.8e-105 351.8 0.7 8.1e-95 318.6 0.0 2.0 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.14 KIK40858.1 - 0.0016 17.5 0.8 0.0023 16.9 0.2 1.4 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase Gemini_V2 PF01524.17 KIK40858.1 - 0.054 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Geminivirus V2 protein STIMATE PF12400.8 KIK40859.1 - 0.13 12.8 9.3 0.57 10.7 0.5 2.7 3 0 0 3 3 3 0 STIMATE family Adeno_GP19K PF04881.13 KIK40859.1 - 3.2 7.8 6.3 2.9 7.9 0.3 2.8 2 1 1 3 3 3 0 Adenovirus GP19K WD40 PF00400.32 KIK40862.1 - 1.3e-30 105.0 22.1 2e-06 28.4 0.7 7.7 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40862.1 - 1.8e-17 63.4 3.1 0.00025 21.3 0.0 5.4 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK40862.1 - 1.3e-07 30.9 1.1 0.069 12.1 0.0 4.4 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK40862.1 - 1.7e-05 23.7 5.8 0.28 9.8 0.1 3.8 2 2 2 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK40862.1 - 3.6e-05 23.2 0.0 0.24 10.7 0.0 2.1 2 0 0 2 2 2 2 WD40-like domain eIF2A PF08662.11 KIK40862.1 - 0.00015 21.7 0.1 0.0014 18.5 0.1 2.3 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK40862.1 - 0.0019 18.1 0.4 23 5.1 0.0 4.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Peptidase_S9_N PF02897.15 KIK40862.1 - 0.0021 17.0 1.1 0.014 14.2 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Cytochrom_D1 PF02239.16 KIK40862.1 - 0.042 12.4 3.0 0.51 8.8 0.1 2.6 2 1 0 2 2 2 0 Cytochrome D1 heme domain Frtz PF11768.8 KIK40862.1 - 0.054 11.8 0.0 3.4 5.9 0.0 2.7 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 KIK40863.1 - 1e-25 89.5 15.5 1e-09 38.8 4.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40863.1 - 1.1e-20 73.6 0.3 0.0016 18.7 0.0 6.3 1 1 6 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK40863.1 - 2.2e-07 30.6 0.7 21 5.2 0.1 6.5 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KIK40863.1 - 1.5e-06 28.2 0.1 0.12 12.2 0.0 3.0 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK40863.1 - 3.6e-06 26.2 0.1 0.2 10.6 0.0 3.6 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 KIK40863.1 - 0.00016 21.4 3.3 0.89 9.6 0.0 5.2 4 1 1 5 5 5 1 PQQ enzyme repeat Nbas_N PF15492.6 KIK40863.1 - 0.00041 19.8 0.8 1.6 8.0 0.1 4.1 2 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK40863.1 - 0.021 13.5 0.1 2.6 6.6 0.0 2.9 1 1 2 3 3 3 0 Nucleoporin Nup120/160 DUF3254 PF11630.8 KIK40863.1 - 0.029 14.6 0.1 0.063 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) Nucleoporin_N PF08801.11 KIK40863.1 - 0.11 11.2 0.0 0.21 10.3 0.0 1.4 2 0 0 2 2 2 0 Nup133 N terminal like Deltaretro_Tax PF05599.11 KIK40867.1 - 0.081 13.4 1.9 3 8.4 0.0 2.2 2 0 0 2 2 2 0 Deltaretrovirus Tax protein Sina PF03145.16 KIK40867.1 - 0.23 11.4 5.1 0.54 10.2 2.5 2.1 1 1 1 2 2 2 0 Seven in absentia protein family Sina PF03145.16 KIK40873.1 - 0.086 12.8 3.6 0.1 12.5 0.3 1.9 1 1 1 2 2 2 0 Seven in absentia protein family Transglut_core3 PF13471.6 KIK40875.1 - 0.07 13.0 0.3 0.12 12.3 0.3 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily Pep1_7 PF17232.2 KIK40878.1 - 0.13 12.7 2.0 5.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Elicitor peptide 1-7 Mito_carr PF00153.27 KIK40879.1 - 7.1e-45 150.9 5.7 2.1e-17 62.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Pro-kuma_activ PF09286.11 KIK40880.1 - 2.3e-45 154.4 0.1 1.1e-44 152.1 0.2 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK40880.1 - 2.3e-05 23.8 3.1 4.1e-05 23.0 3.1 1.4 1 0 0 1 1 1 1 Subtilase family Sulfate_transp PF00916.20 KIK40881.1 - 2.4e-84 283.3 10.2 2.4e-84 283.3 10.2 1.4 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KIK40881.1 - 2e-20 72.5 0.0 3.1e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KIK40881.1 - 8.9e-08 32.4 0.0 1.8e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 STAS domain WD40 PF00400.32 KIK40882.1 - 1.2e-40 136.7 9.7 7.5e-07 29.7 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40882.1 - 2.2e-14 53.5 0.1 0.018 15.3 0.0 5.4 2 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK40882.1 - 2.4e-07 30.8 0.0 0.049 13.5 0.1 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK40882.1 - 3.8e-05 22.5 4.0 0.4 9.3 0.0 3.1 3 0 0 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK40882.1 - 6.1e-05 22.1 4.2 0.37 9.7 0.9 4.5 2 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK40882.1 - 0.00011 22.0 0.0 4 7.5 0.0 4.8 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KIK40882.1 - 0.00016 20.4 0.0 0.023 13.2 0.0 2.9 2 1 0 3 3 3 1 Cytochrome D1 heme domain DUF4875 PF16175.5 KIK40882.1 - 0.15 12.2 0.4 6 7.0 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4875) IKI3 PF04762.12 KIK40882.1 - 0.15 10.0 0.3 2.7 5.9 0.1 2.6 1 1 2 3 3 3 0 IKI3 family Nucleoporin_N PF08801.11 KIK40882.1 - 0.23 10.2 0.1 9.3 4.9 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like TPR_2 PF07719.17 KIK40883.1 - 4.1e-08 32.7 7.2 3.1 8.2 0.1 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIK40883.1 - 2.5e-06 27.0 6.4 1.7 8.6 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK40883.1 - 0.00033 20.5 0.6 7.2 6.9 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIK40883.1 - 0.00068 20.1 3.2 8.1 7.3 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK40883.1 - 0.00078 19.1 2.4 0.55 10.0 0.1 4.2 4 0 0 4 4 4 1 TPR repeat TPR_14 PF13428.6 KIK40883.1 - 0.00096 19.8 7.0 15 6.7 0.1 5.3 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK40883.1 - 0.012 16.3 5.2 3.6 8.3 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 KIK40883.1 - 0.026 15.0 5.7 2.7 8.4 0.1 3.8 3 1 1 4 4 4 0 Bacterial transcriptional activator domain DUF3856 PF12968.7 KIK40883.1 - 0.035 14.2 0.7 29 4.7 0.0 3.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) PPR PF01535.20 KIK40883.1 - 0.043 14.1 0.2 4.7 7.7 0.1 3.3 3 0 0 3 3 3 0 PPR repeat TPR_8 PF13181.6 KIK40883.1 - 0.15 12.3 3.3 40 4.8 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK40883.1 - 0.74 10.4 6.3 14 6.3 0.1 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat HET PF06985.11 KIK40884.1 - 1.1e-10 42.1 4.1 4.3e-10 40.1 0.6 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DHHA2 PF02833.14 KIK40885.1 - 5.7e-19 68.7 1.4 2.1e-18 66.9 1.4 1.9 1 1 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KIK40885.1 - 3.2e-05 24.1 0.0 0.00064 19.9 0.0 2.7 2 1 0 2 2 2 1 DHH family DUF35_N PF12172.8 KIK40886.1 - 0.037 13.9 0.1 0.079 12.9 0.1 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Peptidase_S8 PF00082.22 KIK40889.1 - 2.4e-34 118.9 8.9 3.8e-34 118.3 8.9 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KIK40889.1 - 3.1e-15 56.6 0.0 5.4e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Cyto_heme_lyase PF01265.17 KIK40890.1 - 2.6e-59 201.2 0.7 4.6e-37 128.2 0.5 2.0 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase TBP PF00352.21 KIK40892.1 - 3.5e-66 219.2 0.2 2.9e-32 110.5 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KIK40892.1 - 0.00011 22.2 0.0 0.39 10.9 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KIK40892.1 - 0.11 12.3 0.0 0.31 10.9 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) PROCT PF08084.11 KIK40894.1 - 0.025 14.5 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 PROCT (NUC072) domain tRNA-synt_1b PF00579.25 KIK40895.1 - 4.3e-19 68.9 0.0 3.6e-18 65.9 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Lysine_decarbox PF03641.14 KIK40896.1 - 1.1e-31 109.7 0.0 1.8e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KIK40896.1 - 1.4e-07 31.2 1.3 2.7e-07 30.3 1.3 1.4 1 1 0 1 1 1 1 SLOG cluster4 family Novirhabdo_Nv PF05554.11 KIK40898.1 - 0.033 13.9 0.1 0.034 13.9 0.1 1.1 1 0 0 1 1 1 0 Viral hemorrhagic septicemia virus non-virion protein PI-PLC-X PF00388.19 KIK40899.1 - 0.00082 19.0 0.0 0.0019 17.8 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain MFS_1 PF07690.16 KIK40901.1 - 2.3e-46 158.4 17.5 3.5e-46 157.8 17.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK40901.1 - 1.7e-13 50.2 19.7 1.3e-11 44.1 2.0 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 KIK40901.1 - 0.0013 17.1 7.6 0.0029 16.0 0.5 3.2 2 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family DUF4149 PF13664.6 KIK40901.1 - 0.89 9.9 12.6 1.8 9.0 0.3 4.7 4 1 0 5 5 5 0 Domain of unknown function (DUF4149) zf-C2H2_4 PF13894.6 KIK40902.1 - 0.053 14.4 2.3 3.6 8.7 0.0 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 KIK40902.1 - 0.077 13.6 1.5 0.35 11.5 0.4 2.0 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 KIK40902.1 - 0.21 12.1 8.0 3.4 8.3 0.0 3.1 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK40902.1 - 0.92 10.1 5.6 3.3 8.3 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double domain PRP38 PF03371.15 KIK40903.1 - 1.1e-57 194.8 0.3 1.2e-57 194.5 0.3 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 KIK40903.1 - 0.066 13.8 25.4 0.11 13.2 25.4 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term HEAT_2 PF13646.6 KIK40903.1 - 0.12 12.8 0.0 0.63 10.5 0.0 2.0 2 0 0 2 2 2 0 HEAT repeats DUF2457 PF10446.9 KIK40903.1 - 0.57 9.3 15.1 0.77 8.8 15.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ribosomal_L27A PF00828.19 KIK40904.1 - 5.2e-35 120.9 0.0 7.4e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A IPPT PF01715.17 KIK40905.1 - 1.7e-56 191.6 0.0 5.1e-56 190.0 0.0 1.7 1 1 0 1 1 1 1 IPP transferase AAA_18 PF13238.6 KIK40905.1 - 0.00062 20.3 0.1 0.12 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIK40905.1 - 0.018 15.3 0.2 0.063 13.6 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK40905.1 - 0.024 14.8 0.7 0.64 10.2 0.7 2.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KIK40905.1 - 0.047 13.3 0.1 0.13 11.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK40905.1 - 0.19 12.1 0.1 0.43 11.0 0.1 1.6 1 0 0 1 1 1 0 RNA helicase IPPT PF01715.17 KIK40906.1 - 6.9e-57 192.9 0.0 2.8e-56 190.9 0.0 1.9 1 1 0 1 1 1 1 IPP transferase AAA_18 PF13238.6 KIK40906.1 - 0.00042 20.9 0.1 0.13 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KIK40906.1 - 0.018 15.3 0.2 0.066 13.5 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KIK40906.1 - 0.055 13.0 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK40906.1 - 0.11 12.6 5.8 0.1 12.8 0.4 3.1 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KIK40906.1 - 0.2 12.1 0.1 0.45 10.9 0.1 1.6 1 0 0 1 1 1 0 RNA helicase CbiA PF01656.23 KIK40906.1 - 0.27 11.3 0.6 0.54 10.3 0.6 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PHD PF00628.29 KIK40907.1 - 5.4e-15 55.0 16.3 8.9e-10 38.3 3.6 2.6 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.6 KIK40907.1 - 0.0015 18.2 1.4 0.077 12.6 0.3 2.6 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.6 KIK40907.1 - 0.013 15.7 2.2 0.028 14.7 0.5 2.2 2 0 0 2 2 2 0 PHD-like zinc-binding domain CIAPIN1 PF05093.13 KIK40907.1 - 0.027 15.0 0.5 16 6.1 0.0 3.1 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis PHD_2 PF13831.6 KIK40907.1 - 0.057 13.0 12.1 0.28 10.8 0.9 3.7 3 1 0 3 3 3 0 PHD-finger zf-HC5HC2H_2 PF13832.6 KIK40907.1 - 0.16 12.2 0.7 0.38 10.9 0.1 1.9 2 0 0 2 2 2 0 PHD-zinc-finger like domain C1_1 PF00130.22 KIK40907.1 - 0.2 11.5 4.7 8 6.4 0.3 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 KIK40907.1 - 2.1 8.5 13.1 5.1 7.3 0.9 2.7 2 0 0 2 2 2 0 PHD-finger zf-RING-like PF08746.11 KIK40907.1 - 4.1 7.8 7.3 6.6 7.1 0.5 2.7 2 1 0 2 2 2 0 RING-like domain Transferase PF02458.15 KIK40908.1 - 6.6e-05 21.7 0.0 8.2e-05 21.4 0.0 1.0 1 0 0 1 1 1 1 Transferase family PGM_PMM_I PF02878.16 KIK40910.1 - 8.2e-37 126.0 0.0 1.4e-36 125.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KIK40910.1 - 1e-17 64.3 0.1 1.8e-17 63.6 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KIK40910.1 - 3.4e-17 63.0 0.0 7.5e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KIK40910.1 - 5.6e-05 23.2 0.0 0.00016 21.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain MCM_bind PF09739.9 KIK40911.1 - 3.4e-74 250.4 0.1 1.8e-65 221.5 0.0 3.0 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor CDC50 PF03381.15 KIK40912.1 - 1.6e-90 303.5 0.9 2.5e-90 302.8 0.9 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF1673 PF07895.11 KIK40912.1 - 0.081 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) RTC PF01137.21 KIK40913.1 - 3.6e-82 274.9 0.3 4.1e-82 274.7 0.3 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KIK40913.1 - 6.2e-20 71.6 0.4 1.2e-19 70.7 0.4 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF4212 PF13937.6 KIK40914.1 - 0.0011 19.2 0.3 0.019 15.3 0.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4212) HOOK PF05622.12 KIK40915.1 - 4.1e-65 220.3 45.1 4.1e-65 220.3 45.1 2.1 1 1 1 2 2 2 2 HOOK protein Fez1 PF06818.15 KIK40915.1 - 0.011 16.2 10.3 0.011 16.2 10.3 5.0 2 2 2 4 4 4 0 Fez1 NYD-SP28_assoc PF14775.6 KIK40915.1 - 0.017 15.2 1.1 0.017 15.2 1.1 4.9 5 0 0 5 5 5 0 Sperm tail C-terminal domain bZIP_1 PF00170.21 KIK40915.1 - 0.021 14.9 1.0 0.021 14.9 1.0 8.1 8 1 1 10 10 10 0 bZIP transcription factor TPR_MLP1_2 PF07926.12 KIK40915.1 - 1 9.5 85.5 0.098 12.7 14.2 8.4 3 3 2 6 6 6 0 TPR/MLP1/MLP2-like protein Sugar_tr PF00083.24 KIK40920.1 - 1.4e-80 271.3 11.1 1.9e-80 271.0 11.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK40920.1 - 5.5e-19 68.3 20.7 5.5e-19 68.3 20.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK40920.1 - 0.0027 16.2 3.4 0.004 15.7 3.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3165 PF11364.8 KIK40920.1 - 0.2 12.0 3.2 0.21 11.9 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3165) Alpha-amylase PF00128.24 KIK40922.1 - 4e-50 171.3 0.0 8.6e-50 170.2 0.0 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KIK40922.1 - 9.5e-13 48.2 0.1 2.1e-12 47.2 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) DUF5320 PF17253.2 KIK40926.1 - 0.1 13.7 0.6 0.1 13.7 0.6 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5320) DUF4061 PF13270.6 KIK40926.1 - 0.28 11.5 6.2 0.63 10.4 6.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) Atg14 PF10186.9 KIK40926.1 - 4.9 6.1 10.3 5.9 5.9 10.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PGK PF00162.19 KIK40927.1 - 1.5e-147 491.5 0.1 1.7e-147 491.3 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase JHD PF17811.1 KIK40928.1 - 3.3e-12 46.9 0.1 7.6e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 KIK40928.1 - 6.6e-08 33.0 1.6 1.1e-06 29.0 1.6 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 KIK40928.1 - 6.7e-07 29.1 7.2 1.3e-06 28.2 7.2 1.5 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 KIK40928.1 - 0.0006 19.6 1.3 0.0012 18.7 1.3 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Cupin_8 PF13621.6 KIK40928.1 - 0.00086 19.1 0.5 0.0072 16.1 0.5 2.3 1 1 0 1 1 1 1 Cupin-like domain SRP72 PF08492.12 KIK40928.1 - 0.026 14.9 0.1 0.12 12.8 0.1 2.3 1 0 0 1 1 1 0 SRP72 RNA-binding domain zf-HC5HC2H PF13771.6 KIK40928.1 - 0.053 13.8 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Sel1 PF08238.12 KIK40929.1 - 2.2e-49 164.8 26.3 9e-10 38.9 0.0 7.5 7 0 0 7 7 7 7 Sel1 repeat TPR_14 PF13428.6 KIK40929.1 - 9.2 7.4 17.2 3 8.9 0.6 5.0 5 1 1 6 6 6 0 Tetratricopeptide repeat PITH PF06201.13 KIK40930.1 - 1.5e-26 93.5 0.8 1.7e-26 93.2 0.8 1.1 1 0 0 1 1 1 1 PITH domain PNK3P PF08645.11 KIK40931.1 - 2.2e-45 154.2 0.0 3.3e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KIK40931.1 - 5.5e-15 55.8 0.0 3.4e-12 46.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 KIK40931.1 - 0.0011 18.4 0.5 1.3 8.4 0.1 2.3 1 1 1 2 2 2 2 Chromatin associated protein KTI12 LNS2 PF08235.13 KIK40931.1 - 0.0014 18.2 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) AAA_2 PF07724.14 KIK40932.1 - 9.7e-49 165.8 0.0 5.9e-46 156.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KIK40932.1 - 6.7e-33 112.7 2.0 6.7e-33 112.7 2.0 2.6 1 1 1 2 2 2 1 AAA lid domain AAA PF00004.29 KIK40932.1 - 5.4e-21 75.4 0.1 5.3e-11 43.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KIK40932.1 - 7.9e-21 73.9 3.2 9.3e-21 73.7 0.3 2.6 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KIK40932.1 - 4.1e-18 65.7 0.0 1.5e-11 44.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIK40932.1 - 1.6e-09 38.2 2.7 0.0012 19.1 0.0 5.1 5 2 0 5 5 4 2 AAA domain Sigma54_activat PF00158.26 KIK40932.1 - 3.2e-08 33.5 0.0 8.9e-07 28.8 0.0 2.4 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 KIK40932.1 - 5.2e-08 33.5 7.8 0.021 15.2 0.0 4.7 3 3 1 5 5 4 2 AAA ATPase domain Mg_chelatase PF01078.21 KIK40932.1 - 4.2e-07 29.6 0.3 0.052 12.9 0.1 3.2 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KIK40932.1 - 2.8e-06 27.4 0.0 0.0093 16.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 KIK40932.1 - 4.4e-06 26.6 2.2 0.089 12.5 0.0 3.4 4 0 0 4 4 3 2 IstB-like ATP binding protein AAA_24 PF13479.6 KIK40932.1 - 4.8e-06 26.4 0.0 0.014 15.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KIK40932.1 - 5.9e-06 26.9 0.2 0.27 11.8 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KIK40932.1 - 1.8e-05 24.3 0.0 0.045 13.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region RuvB_N PF05496.12 KIK40932.1 - 3.6e-05 23.5 2.0 0.39 10.4 0.0 3.4 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KIK40932.1 - 3.6e-05 24.0 0.4 0.32 11.2 0.0 3.8 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KIK40932.1 - 5.4e-05 23.7 5.1 0.014 15.9 0.0 3.6 3 1 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 KIK40932.1 - 0.0002 21.3 0.0 0.52 10.2 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase Roc PF08477.13 KIK40932.1 - 0.00024 21.3 0.0 0.42 10.8 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 KIK40932.1 - 0.00061 20.2 0.0 2 8.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 KIK40932.1 - 0.0018 18.2 0.0 0.79 9.6 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.6 KIK40932.1 - 0.0019 18.7 17.6 0.19 12.2 0.0 3.8 3 1 0 3 3 2 1 AAA domain DNA_pol3_delta2 PF13177.6 KIK40932.1 - 0.0035 17.2 0.2 0.058 13.2 0.0 2.8 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA_33 PF13671.6 KIK40932.1 - 0.0042 17.2 0.0 4.2 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain EcoEI_R_C PF08463.10 KIK40932.1 - 0.0043 17.2 2.7 0.013 15.6 2.7 1.9 1 0 0 1 1 1 1 EcoEI R protein C-terminal AAA_29 PF13555.6 KIK40932.1 - 0.0061 16.3 0.0 3.2 7.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KIK40932.1 - 0.0075 15.9 0.3 1.3 8.6 0.0 3.5 3 1 0 3 3 2 1 AAA domain AAA_21 PF13304.6 KIK40932.1 - 0.0092 15.8 4.3 4.7 6.9 0.0 3.8 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_19 PF13245.6 KIK40932.1 - 0.0095 16.3 0.1 0.37 11.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIK40932.1 - 0.031 14.0 4.3 0.95 9.1 0.0 3.8 3 1 0 3 3 3 0 AAA domain AAA_3 PF07726.11 KIK40932.1 - 0.032 14.1 0.0 19 5.1 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KIK40932.1 - 0.042 13.9 0.0 9.6 6.2 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_15 PF13175.6 KIK40932.1 - 0.059 13.1 0.4 54 3.3 0.3 3.1 3 0 0 3 3 3 0 AAA ATPase domain Spc42p PF11544.8 KIK40932.1 - 0.062 13.3 2.4 0.17 11.9 2.4 1.7 1 0 0 1 1 1 0 Spindle pole body component Spc42p SRP54 PF00448.22 KIK40932.1 - 0.069 12.8 0.0 7.7 6.1 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 KIK40932.1 - 0.071 13.0 8.4 12 5.7 0.0 4.5 3 2 2 5 5 5 0 ATPase domain predominantly from Archaea Bacillus_HBL PF05791.11 KIK40932.1 - 0.076 12.8 2.1 0.16 11.8 2.1 1.5 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) NTPase_1 PF03266.15 KIK40932.1 - 0.084 12.8 3.2 6.5 6.6 0.0 4.2 5 0 0 5 5 5 0 NTPase MMR_HSR1 PF01926.23 KIK40932.1 - 0.11 12.6 0.6 24 5.1 0.0 3.4 3 1 0 3 3 3 0 50S ribosome-binding GTPase UPF0242 PF06785.11 KIK40932.1 - 0.12 12.4 8.1 0.23 11.6 8.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Pox_A_type_inc PF04508.12 KIK40932.1 - 0.27 11.1 7.3 0.15 12.0 0.4 3.6 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat FapA PF03961.13 KIK40932.1 - 2 6.9 6.4 1.8 7.0 4.8 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A Atg14 PF10186.9 KIK40932.1 - 4.4 6.3 7.0 6.8 5.7 7.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KIK40932.1 - 8 7.0 15.4 21 5.6 15.4 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region RNase_PH PF01138.21 KIK40933.1 - 1.6e-16 61.0 0.0 2.6e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KIK40933.1 - 3.6e-09 36.5 0.0 6.1e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Trm112p PF03966.16 KIK40934.1 - 1e-19 70.8 0.0 1.4e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Trm112p-like protein A2L_zn_ribbon PF08792.10 KIK40934.1 - 0.017 14.8 0.1 0.017 14.8 0.1 1.9 2 0 0 2 2 2 0 A2L zinc ribbon domain AurF PF11583.8 KIK40934.1 - 0.047 13.0 0.2 0.054 12.8 0.2 1.1 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF His_kinase PF06580.13 KIK40934.1 - 0.088 13.1 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase GalP_UDP_transf PF01087.22 KIK40935.1 - 2.7e-60 203.9 0.0 4.4e-60 203.3 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KIK40935.1 - 1.2e-45 155.3 0.1 1.8e-45 154.6 0.1 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 KIK40935.1 - 0.046 12.5 0.1 7.2 5.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4921) DcpS_C PF11969.8 KIK40935.1 - 0.15 12.5 4.9 0.14 12.6 2.2 2.2 2 1 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KIK40935.1 - 0.25 12.1 7.2 2.7 8.8 3.7 3.1 2 1 0 2 2 2 0 HIT domain SAE2 PF08573.10 KIK40936.1 - 5.5e-20 72.5 2.5 6.2e-20 72.4 0.6 2.2 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus SKA2 PF16740.5 KIK40936.1 - 0.0016 18.2 0.0 0.0043 16.8 0.0 1.7 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 CENP-Q PF13094.6 KIK40936.1 - 0.007 16.6 0.5 0.055 13.7 0.0 2.5 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit NUDIX PF00293.28 KIK40937.1 - 6.9e-15 55.2 0.2 1.3e-14 54.4 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain SDA1 PF05285.12 KIK40938.1 - 2.4e-85 287.1 33.4 3.7e-44 151.6 5.3 3.1 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.12 KIK40938.1 - 6.4e-26 90.4 0.0 2.1e-25 88.8 0.0 2.0 1 0 0 1 1 1 1 NUC130/3NT domain NESP55 PF06390.12 KIK40938.1 - 0.0089 15.7 3.4 0.0089 15.7 3.4 1.7 2 0 0 2 2 2 1 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.11 KIK40938.1 - 0.56 10.2 7.2 1.8 8.6 7.2 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DEAD PF00270.29 KIK40939.1 - 2.3e-22 79.6 0.0 4e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK40939.1 - 1.5e-16 60.7 0.0 8.6e-16 58.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KIK40939.1 - 6.9e-13 49.1 2.0 2.5e-12 47.3 2.0 2.1 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 KIK40939.1 - 1.1e-11 44.5 0.0 2.9e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 RQC domain ResIII PF04851.15 KIK40939.1 - 5.2e-05 23.3 0.0 0.00034 20.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIK40939.1 - 0.089 13.1 0.2 0.59 10.4 0.2 2.4 1 1 1 2 2 2 0 AAA domain Nuf2 PF03800.14 KIK40940.1 - 4.1e-33 114.4 0.1 1.3e-32 112.8 0.1 1.9 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 KIK40940.1 - 6.6e-32 110.0 24.2 6.6e-32 110.0 24.2 3.7 3 1 0 3 3 3 1 Designed helical repeat protein 10 domain APG6_N PF17675.1 KIK40940.1 - 0.0016 19.0 54.9 0.17 12.4 10.2 4.0 3 2 1 4 4 4 3 Apg6 coiled-coil region BST2 PF16716.5 KIK40940.1 - 0.027 15.0 12.5 0.027 15.0 12.5 4.3 1 1 3 4 4 4 0 Bone marrow stromal antigen 2 DUF148 PF02520.17 KIK40940.1 - 0.028 14.5 1.8 0.028 14.5 1.8 4.4 2 2 2 4 4 4 0 Domain of unknown function DUF148 UPF0242 PF06785.11 KIK40940.1 - 0.21 11.7 45.0 0.16 12.0 7.1 3.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 KIK40940.1 - 0.35 10.2 50.1 1.1 8.6 22.0 3.4 2 2 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4201 PF13870.6 KIK40940.1 - 0.4 10.4 39.9 0.53 10.0 19.9 3.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) Scaffolding_pro PF11418.8 KIK40940.1 - 0.64 10.6 13.5 5.4 7.6 0.4 4.3 2 2 2 4 4 4 0 Phi29 scaffolding protein ING PF12998.7 KIK40940.1 - 0.87 10.2 20.8 0.17 12.5 7.2 3.5 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding MAD PF05557.13 KIK40940.1 - 0.95 7.8 48.6 1.8 6.8 32.8 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein Mt_ATP-synt_D PF05873.12 KIK40940.1 - 2.9 7.7 20.3 0.041 13.7 8.4 3.0 2 2 1 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) STATa_Ig PF18214.1 KIK40940.1 - 4.4 7.3 8.9 1.7 8.7 0.3 3.3 1 1 1 3 3 3 0 STATa Immunoglobulin-like domain ING PF12998.7 KIK40941.1 - 1.2e-13 51.5 1.6 4.4e-07 30.4 0.2 2.3 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KIK40941.1 - 4.3e-05 23.3 7.0 7.5e-05 22.6 7.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KIK40941.1 - 0.023 14.2 1.6 0.04 13.5 1.6 1.4 1 0 0 1 1 1 0 PHD-finger Pkinase_Tyr PF07714.17 KIK40942.1 - 4.6e-35 121.1 0.0 7.4e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK40942.1 - 9.2e-31 107.2 0.0 1.7e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KIK40942.1 - 0.0013 18.1 0.0 0.003 16.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like HEAT_2 PF13646.6 KIK40943.1 - 2.9e-09 37.2 6.6 0.043 14.2 0.2 7.4 4 2 3 7 7 7 2 HEAT repeats HEAT PF02985.22 KIK40943.1 - 8.9e-08 31.8 14.1 2.4 8.6 0.0 10.9 11 0 0 11 11 11 2 HEAT repeat Adaptin_N PF01602.20 KIK40943.1 - 2e-06 26.7 0.7 0.024 13.2 0.0 3.1 3 0 0 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.6 KIK40943.1 - 5.4e-05 23.6 18.0 0.046 14.2 0.1 8.3 9 0 0 9 9 9 1 HEAT-like repeat RTP1_C1 PF10363.9 KIK40943.1 - 6.5e-05 23.1 2.6 0.29 11.3 1.3 4.6 2 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KIK40943.1 - 0.0085 16.1 4.7 0.17 12.0 0.1 4.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KIK40943.1 - 0.011 15.8 0.2 4.1 7.4 0.5 4.0 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Rft-1 PF04506.13 KIK40944.1 - 6.9e-124 414.4 14.2 8.6e-124 414.1 14.2 1.0 1 0 0 1 1 1 1 Rft protein Zn_clus PF00172.18 KIK40946.1 - 0.00045 20.3 16.6 0.00064 19.8 16.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIF4G PF02854.19 KIK40955.1 - 4e-45 154.1 0.1 7.4e-28 97.6 0.0 3.5 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 KIK40955.1 - 3.4e-25 89.3 0.3 3.4e-25 89.3 0.3 3.2 2 1 1 3 3 3 1 Up-frameshift suppressor 2 Ntox1 PF15500.6 KIK40955.1 - 7.7 6.9 8.1 21 5.5 3.3 2.7 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 RRM_2 PF04059.12 KIK40956.1 - 4.6e-34 116.5 0.9 6.1e-34 116.1 0.9 1.2 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 KIK40956.1 - 0.00068 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KIK40956.1 - 0.018 15.2 0.2 0.062 13.5 0.2 1.7 1 1 1 2 2 2 0 BRCA1-associated protein 2 Smg4_UPF3 PF03467.15 KIK40956.1 - 0.16 11.9 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Smg-4/UPF3 family Ribosomal_S6 PF01250.17 KIK40957.1 - 1e-12 48.1 0.1 1.5e-12 47.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 HAD_2 PF13419.6 KIK40958.1 - 8.8e-10 39.0 0.0 1.1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIK40958.1 - 3.1e-06 27.1 0.1 5.5e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KIK40958.1 - 5.6e-05 23.5 0.0 7.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-RING_2 PF13639.6 KIK40959.1 - 4.8e-10 39.6 2.0 6.9e-08 32.7 0.4 2.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KIK40959.1 - 3.8e-09 36.7 1.2 7.7e-08 32.5 0.1 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KIK40959.1 - 2.5e-08 33.6 5.0 1.2e-07 31.5 1.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIK40959.1 - 4.4e-07 29.5 2.7 0.00021 21.0 0.0 2.9 3 0 0 3 3 3 2 RING-like zinc finger zf-C3HC4 PF00097.25 KIK40959.1 - 1.3e-06 28.2 0.4 6.1e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK40959.1 - 4.2e-05 23.3 0.4 4.2e-05 23.3 0.4 2.1 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KIK40959.1 - 0.00011 22.1 7.8 0.0016 18.4 1.1 3.4 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIK40959.1 - 0.0002 21.3 0.2 0.0002 21.3 0.2 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KIK40959.1 - 0.00027 20.9 0.4 0.00092 19.2 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KIK40959.1 - 0.0033 17.0 4.3 0.0076 15.9 1.1 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KIK40959.1 - 0.0038 17.0 3.1 0.0048 16.7 0.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK40959.1 - 0.018 15.2 2.3 0.045 13.9 0.3 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KIK40959.1 - 0.023 14.5 0.5 0.1 12.5 0.3 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 KIK40959.1 - 0.067 13.1 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING-like PF08746.11 KIK40959.1 - 0.095 13.0 0.8 0.23 11.8 0.8 1.6 1 0 0 1 1 1 0 RING-like domain Rad50_zn_hook PF04423.14 KIK40959.1 - 0.1 12.4 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif FANCL_C PF11793.8 KIK40959.1 - 0.12 12.5 3.7 0.7 10.1 1.7 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain CTU2 PF10288.9 KIK40959.1 - 0.41 10.9 3.7 2.9 8.2 1.1 2.4 1 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-RING_4 PF14570.6 KIK40959.1 - 0.87 9.4 2.8 0.37 10.6 0.3 1.7 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain DUF3533 PF12051.8 KIK40960.1 - 6.2e-97 324.9 14.8 7.5e-97 324.6 14.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Ferrochelatase PF00762.19 KIK40964.1 - 3.7e-102 341.7 0.0 4.2e-102 341.5 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 KIK40964.1 - 0.039 14.3 0.0 8.9 6.7 0.0 3.0 3 0 0 3 3 3 0 CbiX GHMP_kinases_N PF00288.26 KIK40965.1 - 5.5e-11 42.5 5.1 8.6e-11 41.9 2.4 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KIK40965.1 - 2.2e-07 31.1 0.0 5.9e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Aa_trans PF01490.18 KIK40966.1 - 1.7e-69 234.5 26.0 2e-69 234.3 26.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KIK40966.1 - 0.00015 21.0 12.8 0.00015 21.0 12.8 2.0 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF2574 PF10836.8 KIK40966.1 - 0.036 13.9 0.4 4 7.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2574) DUF1080 PF06439.11 KIK40967.1 - 0.065 13.3 0.1 0.13 12.3 0.1 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1080) Fe_hyd_lg_C PF02906.14 KIK40968.1 - 9.5e-62 208.8 0.0 1.7e-61 208.0 0.0 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain zf-C2H2_jaz PF12171.8 KIK40969.1 - 0.22 11.8 0.3 0.22 11.8 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding SNARE PF05739.19 KIK40970.1 - 1.5e-15 56.9 1.4 1.9e-15 56.6 0.2 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KIK40970.1 - 5.6e-05 22.9 4.3 5.6e-05 22.9 4.3 1.8 2 0 0 2 2 2 1 Syntaxin EDR1 PF14381.6 KIK40970.1 - 0.0024 17.6 0.5 0.068 12.9 0.4 2.3 2 0 0 2 2 2 1 Ethylene-responsive protein kinase Le-CTR1 Peptidase_C1_2 PF03051.15 KIK40972.1 - 4.3e-158 526.7 0.0 5e-158 526.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KIK40972.1 - 2.1e-08 34.5 0.1 0.0018 18.4 0.0 2.5 2 0 0 2 2 2 2 Papain family cysteine protease Na_H_Exchanger PF00999.21 KIK40973.1 - 1.8e-55 188.3 23.5 2.1e-55 188.1 23.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 KIK40973.1 - 0.45 10.6 5.8 0.52 10.4 0.0 3.3 3 0 0 3 3 3 0 YrhC-like protein Pkinase_fungal PF17667.1 KIK40977.1 - 2e-18 66.4 0.6 2.2e-18 66.2 0.6 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 KIK40978.1 - 9.1e-16 57.6 1.9 4.8e-11 42.1 0.1 3.1 1 1 1 2 2 2 2 Fungal protein kinase Methyltransf_31 PF13847.6 KIK40979.1 - 6e-25 87.8 0.0 8e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK40979.1 - 1.1e-18 67.7 0.0 1.6e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK40979.1 - 8.4e-14 52.1 0.0 1.2e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK40979.1 - 1.4e-13 51.2 0.0 2.2e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK40979.1 - 1e-12 48.2 0.0 1.5e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK40979.1 - 2.1e-10 40.3 0.0 2.8e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KIK40979.1 - 4.4e-08 33.1 0.0 2.4e-07 30.7 0.0 1.7 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KIK40979.1 - 9.8e-05 21.8 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 KIK40979.1 - 0.00054 19.4 0.0 0.00082 18.8 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 KIK40979.1 - 0.0015 18.0 0.0 0.0028 17.1 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KIK40979.1 - 0.0031 17.1 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 KIK40979.1 - 0.0032 16.4 0.0 0.0053 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 KIK40979.1 - 0.008 15.8 0.0 0.014 15.0 0.0 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_PK PF05891.12 KIK40979.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltr_RsmB-F PF01189.17 KIK40979.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_29 PF03141.16 KIK40979.1 - 0.029 12.9 0.1 0.049 12.2 0.0 1.4 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 KIK40979.1 - 0.03 13.6 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain CheR PF01739.18 KIK40979.1 - 0.047 13.2 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain SH3_9 PF14604.6 KIK40980.1 - 9.1e-07 28.7 0.1 2.2e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIK40980.1 - 0.00073 19.1 0.0 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KIK40980.1 - 0.0076 15.9 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CID_GANP PF16766.5 KIK40981.1 - 0.059 13.6 0.0 0.095 12.9 0.0 1.2 1 0 0 1 1 1 0 Binding region of GANP to ENY2 IMPDH PF00478.25 KIK40982.1 - 7.2e-131 436.3 0.0 1.5e-130 435.3 0.0 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KIK40982.1 - 2.6e-13 50.2 0.0 7e-07 29.6 0.0 3.1 3 0 0 3 3 3 2 CBS domain FMN_dh PF01070.18 KIK40982.1 - 5.4e-11 42.1 0.5 1.2e-10 41.0 0.6 1.5 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 KIK40982.1 - 4.1e-09 36.3 2.3 8.1e-08 32.0 1.5 2.2 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 KIK40982.1 - 3.7e-06 26.6 2.6 0.00015 21.3 0.5 2.4 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 KIK40982.1 - 0.0018 17.6 0.9 0.0034 16.7 0.9 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 KIK40982.1 - 0.013 14.7 0.1 0.032 13.4 0.1 1.7 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase DUF561 PF04481.12 KIK40982.1 - 0.013 14.7 0.9 0.097 11.8 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF561) G3P_antiterm PF04309.12 KIK40982.1 - 0.024 14.1 1.1 0.5 9.8 0.2 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Dus PF01207.17 KIK40982.1 - 0.026 13.6 1.3 0.73 8.9 0.1 2.1 1 1 0 2 2 2 0 Dihydrouridine synthase (Dus) Aldolase PF01081.19 KIK40982.1 - 0.052 13.0 0.2 0.64 9.4 0.4 2.5 2 1 0 2 2 2 0 KDPG and KHG aldolase DHO_dh PF01180.21 KIK40982.1 - 0.22 10.7 3.7 0.2 10.9 0.5 2.0 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase WD40 PF00400.32 KIK40983.1 - 9.5e-38 127.5 32.5 6.4e-07 30.0 1.6 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40983.1 - 2.1e-19 69.6 7.4 0.00011 22.4 0.1 6.8 1 1 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK40983.1 - 2e-08 33.6 0.3 0.098 11.6 0.0 4.7 2 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK40983.1 - 7.6e-05 21.5 6.2 0.24 10.0 0.0 5.3 4 2 1 5 5 5 1 Nucleoporin Nup120/160 SGL PF08450.12 KIK40983.1 - 0.00052 19.7 0.9 0.19 11.3 0.0 3.3 3 1 1 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region DUF5046 PF16465.5 KIK40983.1 - 0.00063 19.3 0.0 1.7 8.0 0.0 3.8 1 1 2 3 3 3 1 Domain of unknown function (DUF5046) PQQ PF01011.21 KIK40983.1 - 0.0012 18.7 0.3 16 5.6 0.0 4.7 4 0 0 4 4 4 0 PQQ enzyme repeat Nbas_N PF15492.6 KIK40983.1 - 0.0064 15.9 2.5 1 8.6 0.1 3.6 1 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KIK40983.1 - 0.0087 16.0 5.0 3.2 7.8 0.0 4.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Hira PF07569.11 KIK40983.1 - 0.009 15.8 7.8 7.1 6.3 0.0 5.1 4 3 1 5 5 5 1 TUP1-like enhancer of split PQQ_3 PF13570.6 KIK40983.1 - 0.019 15.5 3.6 12 6.6 0.0 4.5 5 0 0 5 5 5 0 PQQ-like domain eIF2A PF08662.11 KIK40983.1 - 0.021 14.7 0.3 0.83 9.5 0.0 2.5 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK40983.1 - 0.034 13.5 0.2 7.2 5.8 0.0 2.8 4 0 0 4 4 4 0 WD40-like domain Coatomer_WDAD PF04053.14 KIK40983.1 - 0.072 12.1 0.1 0.63 9.0 0.0 2.2 3 0 0 3 3 3 0 Coatomer WD associated region DUF3511 PF12023.8 KIK40985.1 - 0.2 11.5 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3511) WD40 PF00400.32 KIK40986.1 - 1e-37 127.5 21.9 1.8e-09 38.0 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK40986.1 - 2e-16 60.1 0.4 8.2e-05 22.8 0.0 4.3 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK40986.1 - 2.6e-08 33.2 0.0 0.12 11.3 0.0 4.5 1 1 4 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK40986.1 - 3.7e-08 32.5 0.1 0.0088 14.7 0.1 3.4 1 1 3 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK40986.1 - 0.0012 18.7 0.0 0.044 13.6 0.0 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.9 KIK40986.1 - 0.0018 18.1 0.1 0.61 9.8 0.0 3.1 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.11 KIK40986.1 - 0.034 12.9 0.6 1.6 7.4 0.2 2.6 2 1 1 3 3 3 0 Nup133 N terminal like Glucodextran_C PF09985.9 KIK40986.1 - 0.056 12.9 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 C-terminal binding-module, SLH-like, of glucodextranase WD40_like PF17005.5 KIK40986.1 - 0.058 12.7 0.0 10 5.4 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain RAB3GAP2_N PF14655.6 KIK40986.1 - 0.11 11.8 0.0 4.1 6.6 0.0 2.2 2 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Pkinase_fungal PF17667.1 KIK40988.1 - 9.8e-46 156.3 0.0 4.4e-24 85.0 0.1 2.9 2 1 1 3 3 3 2 Fungal protein kinase Pkinase PF00069.25 KIK40988.1 - 9e-06 25.2 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK40988.1 - 0.048 13.6 0.2 0.13 12.1 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family TIP49 PF06068.13 KIK40995.1 - 2.9e-157 523.4 0.0 3.5e-157 523.1 0.0 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KIK40995.1 - 3.8e-18 65.4 0.0 8.3e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KIK40995.1 - 9.9e-10 39.0 0.1 3.6e-06 27.4 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KIK40995.1 - 1.9e-08 34.2 0.0 9.2e-07 28.7 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KIK40995.1 - 7.5e-07 29.5 0.0 0.013 15.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KIK40995.1 - 6.8e-06 26.1 0.1 0.0037 17.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIK40995.1 - 2.6e-05 24.7 0.0 0.00023 21.6 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KIK40995.1 - 0.0015 18.8 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KIK40995.1 - 0.0018 17.9 0.1 0.0038 16.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK40995.1 - 0.0032 17.8 0.8 0.039 14.3 0.8 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIK40995.1 - 0.016 15.3 0.0 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KIK40995.1 - 0.029 14.9 0.0 0.16 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KIK40995.1 - 0.033 13.6 0.1 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KIK40995.1 - 0.045 13.4 0.0 4 7.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KIK40995.1 - 0.048 13.4 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KIK40995.1 - 0.053 13.0 0.1 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KIK40995.1 - 0.06 12.6 0.1 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin ResIII PF04851.15 KIK40995.1 - 0.09 12.8 0.0 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KIK40995.1 - 0.21 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PNP_UDP_1 PF01048.20 KIK40998.1 - 3.3e-32 111.6 0.0 3.9e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Pkinase_fungal PF17667.1 KIK40999.1 - 1.4e-05 24.1 0.0 1.4e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 KIK41000.1 - 2.1e-45 155.3 0.1 3.2e-24 85.5 0.1 2.9 1 1 1 3 3 3 2 Fungal protein kinase Pkinase PF00069.25 KIK41000.1 - 1.3e-06 28.0 0.0 2.6e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK41000.1 - 0.098 12.6 0.4 0.37 10.7 0.1 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK41001.1 - 2.7e-21 75.8 0.6 1.2e-19 70.4 0.1 2.0 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIK41001.1 - 1.6e-06 27.7 0.0 3.8e-06 26.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 KIK41002.1 - 4.2e-19 68.6 0.0 5.3e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK41002.1 - 0.051 12.9 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DUF1668 PF07893.13 KIK41004.1 - 0.015 14.7 0.6 3.1 7.1 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) PQQ_3 PF13570.6 KIK41004.1 - 0.037 14.5 6.8 2.8 8.6 0.0 4.8 4 1 1 5 5 5 0 PQQ-like domain MFS_1 PF07690.16 KIK41005.1 - 2.6e-38 131.9 42.0 2.6e-38 131.9 42.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK41005.1 - 2.3e-06 26.8 0.8 2.3e-06 26.8 0.8 4.0 3 3 1 4 4 4 2 Sugar (and other) transporter MFS_1 PF07690.16 KIK41006.1 - 5.6e-12 45.2 10.3 7e-12 44.9 10.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Pkinase_fungal PF17667.1 KIK41007.1 - 1.4e-23 83.4 0.0 2.2e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KIK41007.1 - 0.0007 19.0 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Glyco_transf_5 PF08323.11 KIK41007.1 - 0.092 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Starch synthase catalytic domain DUF4256 PF14066.6 KIK41007.1 - 0.14 11.8 0.0 0.38 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4256) Amino_oxidase PF01593.24 KIK41009.1 - 4e-58 197.8 0.3 2.1e-24 86.7 0.0 3.0 1 1 1 3 3 3 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK41009.1 - 1.5e-11 44.4 0.2 3.6e-11 43.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK41009.1 - 1.2e-05 24.7 0.1 0.0015 17.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIK41009.1 - 4.9e-05 22.9 0.1 0.0001 21.8 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIK41009.1 - 0.00015 21.1 0.2 0.00027 20.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KIK41009.1 - 0.00044 19.6 0.0 0.00067 19.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KIK41009.1 - 0.0014 18.0 0.4 0.0082 15.4 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK41009.1 - 0.0014 18.3 0.7 0.0029 17.2 0.4 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK41009.1 - 0.0048 16.0 0.2 0.0072 15.4 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 KIK41009.1 - 0.0067 16.5 0.1 0.012 15.7 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KIK41009.1 - 0.0073 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KIK41009.1 - 0.013 16.1 3.4 0.03 14.9 0.1 2.5 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK41009.1 - 0.12 11.1 0.9 0.19 10.4 0.3 1.6 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 KIK41009.1 - 0.18 11.8 0.6 5.5 7.0 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF1242 PF06842.12 KIK41012.1 - 7.6e-18 64.0 2.0 1e-17 63.6 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) LST1 PF05083.13 KIK41012.1 - 0.15 12.4 2.0 0.21 11.9 1.4 1.4 1 1 0 1 1 1 0 LST-1 protein SMC_N PF02463.19 KIK41013.1 - 3.4e-60 203.2 26.1 1.8e-59 200.8 26.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KIK41013.1 - 5.1e-20 71.9 2.2 1.6e-19 70.3 0.4 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KIK41013.1 - 2.6e-11 43.9 2.5 3.4e-05 23.8 0.1 3.1 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIK41013.1 - 3.2e-10 40.8 30.4 3.2e-10 40.8 30.4 7.4 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.6 KIK41013.1 - 5.8e-05 22.7 0.0 0.0002 21.0 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain BST2 PF16716.5 KIK41013.1 - 0.015 15.8 7.5 0.015 15.8 7.5 9.1 6 2 4 10 10 10 0 Bone marrow stromal antigen 2 ATG16 PF08614.11 KIK41013.1 - 2 8.6 115.2 1.5 9.0 15.0 7.4 2 2 4 7 7 7 0 Autophagy protein 16 (ATG16) DUF262 PF03235.14 KIK41014.1 - 1.5e-13 51.4 0.8 1.5e-13 51.4 0.8 2.3 2 1 0 2 2 2 1 Protein of unknown function DUF262 DUF1580 PF07618.11 KIK41014.1 - 0.12 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1580) RSB_motif PF16294.5 KIK41014.1 - 0.27 11.5 4.0 0.62 10.4 4.0 1.7 1 1 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif Glyco_hydro_88 PF07470.13 KIK41015.1 - 1.6e-20 73.5 0.4 2.3e-20 73.0 0.4 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF1905 PF08922.11 KIK41015.1 - 0.018 15.1 0.0 0.94 9.6 0.0 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF1905) NIF PF03031.18 KIK41016.1 - 1.8e-14 53.8 0.0 4e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF262 PF03235.14 KIK41018.1 - 2.2e-18 67.3 0.6 4.9e-18 66.1 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF262 MAD PF05557.13 KIK41019.1 - 3.7e-47 161.1 54.8 5.1e-47 160.6 54.8 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein ATG16 PF08614.11 KIK41019.1 - 4.5 7.5 98.9 0.028 14.6 16.8 6.8 3 1 4 7 7 7 0 Autophagy protein 16 (ATG16) Pkinase_fungal PF17667.1 KIK41021.1 - 4e-20 72.0 0.2 4.5e-13 48.8 0.2 2.1 1 1 1 2 2 2 2 Fungal protein kinase NAGLU PF05089.12 KIK41023.1 - 1.4e-130 435.2 1.6 2e-130 434.6 1.6 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 KIK41023.1 - 2.8e-70 236.9 0.6 3.9e-70 236.4 0.6 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 KIK41023.1 - 2.9e-18 65.4 0.0 5.5e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Peptidase_M24 PF00557.24 KIK41024.1 - 3.2e-56 190.3 0.0 1.2e-55 188.5 0.0 1.8 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KIK41024.1 - 1.9e-20 72.9 0.0 3.6e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain CBF PF03914.17 KIK41026.1 - 5.3e-38 130.7 0.1 5.3e-38 130.7 0.1 2.9 3 0 0 3 3 3 1 CBF/Mak21 family Cnd1 PF12717.7 KIK41026.1 - 0.0074 16.3 0.1 0.062 13.3 0.0 2.1 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KIK41026.1 - 0.042 12.4 0.5 0.1 11.1 0.1 1.8 2 0 0 2 2 2 0 Adaptin N terminal region BUD22 PF09073.10 KIK41026.1 - 0.25 10.6 28.4 0.032 13.6 22.2 2.3 2 0 0 2 2 2 0 BUD22 Mid1 PF12929.7 KIK41028.1 - 1.5e-52 179.3 0.0 1.9e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KIK41028.1 - 0.00017 22.2 4.9 0.011 16.3 1.0 2.5 2 0 0 2 2 2 2 Fz domain Dimer_Tnp_hAT PF05699.14 KIK41029.1 - 3.1e-07 30.1 0.4 1e-06 28.4 0.1 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF5576 PF17739.1 KIK41029.1 - 0.069 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5576) YcaO PF02624.16 KIK41029.1 - 0.083 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding Chol_subst-bind PF09129.11 KIK41033.1 - 0.15 11.0 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding Plavaka PF18759.1 KIK41034.1 - 6.1e-26 91.4 0.2 3.6e-15 56.0 0.1 2.3 2 0 0 2 2 2 2 Plavaka transposase CDC45 PF02724.14 KIK41036.1 - 0.031 12.6 8.1 0.011 14.0 3.7 1.9 2 0 0 2 2 2 0 CDC45-like protein Tombus_P33 PF08500.10 KIK41036.1 - 0.27 11.2 3.4 17 5.4 0.0 2.4 2 0 0 2 2 2 0 Tombusvirus p33 Zip PF02535.22 KIK41036.1 - 0.53 9.4 5.6 0.19 10.9 2.4 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter SDA1 PF05285.12 KIK41036.1 - 0.75 9.2 18.8 0.29 10.5 11.4 2.2 2 0 0 2 2 2 0 SDA1 TAF4 PF05236.14 KIK41036.1 - 1.5 8.5 12.6 1.9 8.2 0.2 2.7 3 0 0 3 3 3 0 Transcription initiation factor TFIID component TAF4 family Presenilin PF01080.17 KIK41036.1 - 1.8 7.2 5.0 1.5 7.5 2.0 2.0 2 0 0 2 2 2 0 Presenilin DUF4770 PF15994.5 KIK41036.1 - 2.4 8.4 5.8 1.8 8.7 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) CPSF100_C PF13299.6 KIK41036.1 - 3.4 7.8 8.9 1.4 9.1 2.2 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Nop14 PF04147.12 KIK41036.1 - 3.8 5.6 14.8 0.68 8.1 9.8 1.9 2 0 0 2 2 2 0 Nop14-like family SPRY PF00622.28 KIK41040.1 - 4e-10 39.8 0.0 6.5e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 SPRY domain MFS_1 PF07690.16 KIK41041.1 - 1.4e-20 73.6 47.7 1.3e-14 53.9 10.8 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK41041.1 - 5e-18 65.2 22.6 2.2e-17 63.1 6.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter CHAT PF12770.7 KIK41043.1 - 1.3e-17 64.2 0.0 2.5e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK41043.1 - 6.9e-05 22.6 20.6 19 5.3 0.0 9.9 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK41043.1 - 0.00024 21.0 5.5 0.07 13.4 0.2 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK41043.1 - 0.00065 19.4 14.1 0.016 15.0 0.7 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIK41043.1 - 0.0011 19.2 3.5 0.024 14.9 0.4 8.1 8 3 2 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIK41043.1 - 0.0039 17.9 22.1 1.4 10.0 0.0 8.4 8 1 1 9 9 9 2 Tetratricopeptide repeat DUF4404 PF14357.6 KIK41043.1 - 0.0072 16.9 1.0 0.52 11.0 0.2 3.6 3 1 0 3 3 3 1 Domain of unknown function (DUF4404) TPR_2 PF07719.17 KIK41043.1 - 0.043 13.9 0.5 0.043 13.9 0.5 7.7 9 0 0 9 9 9 0 Tetratricopeptide repeat SNAP PF14938.6 KIK41043.1 - 0.3 10.5 3.6 15 4.9 0.1 4.0 4 1 1 5 5 5 0 Soluble NSF attachment protein, SNAP MIT PF04212.18 KIK41043.1 - 2.9 8.0 6.1 11 6.2 0.1 4.1 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain Ebp2 PF05890.12 KIK41044.1 - 1.3e-85 287.2 9.6 1.3e-85 287.2 9.6 1.5 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 DUF3510 PF12022.8 KIK41044.1 - 8 6.9 7.5 1.1 9.7 2.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3510) CHAT PF12770.7 KIK41045.1 - 5e-32 111.5 0.0 8e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK41045.1 - 2.7e-15 55.7 3.2 0.42 10.6 0.0 8.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 KIK41045.1 - 1.4e-07 31.0 7.4 7.8 6.5 0.0 8.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK41045.1 - 2.5e-07 30.3 3.0 32 5.0 0.0 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIK41045.1 - 9.2e-07 29.1 13.3 0.94 9.8 0.0 8.0 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK41045.1 - 9.5e-06 25.6 6.9 0.64 10.5 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK41045.1 - 3.9e-05 23.3 1.7 1.5 8.6 0.1 5.1 5 1 0 5 5 5 2 TPR repeat FRB_dom PF08771.11 KIK41045.1 - 0.042 14.3 0.0 55 4.3 0.0 4.2 4 0 0 4 4 4 0 FKBP12-rapamycin binding domain TPR_16 PF13432.6 KIK41045.1 - 0.16 12.6 7.5 25 5.6 0.0 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat zf_CCCH_5 PF18384.1 KIK41048.1 - 0.051 13.7 0.5 0.083 13.0 0.5 1.3 1 0 0 1 1 1 0 Unkempt Zinc finger domain 1 (Znf1) HAD_2 PF13419.6 KIK41049.1 - 5.6e-16 59.1 0.0 5.9e-11 42.8 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK41049.1 - 2.6e-11 44.2 0.0 9.5e-11 42.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIK41049.1 - 6.4e-05 22.9 0.3 0.00013 22.0 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like LMWPc PF01451.21 KIK41050.1 - 1.8e-27 96.4 0.0 2.1e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase F-box-like PF12937.7 KIK41051.1 - 1.6e-06 27.9 0.1 3.8e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK41051.1 - 1.5e-05 24.7 0.0 3.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KIK41051.1 - 0.061 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 F-box Abhydrolase_6 PF12697.7 KIK41054.1 - 9.3e-07 29.7 0.7 1.4e-06 29.1 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3759 PF12585.8 KIK41055.1 - 2.1e-37 127.0 5.3 2.5e-37 126.8 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) AHH PF14412.6 KIK41056.1 - 0.031 14.4 0.0 0.031 14.4 0.0 1.0 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH bZIP_1 PF00170.21 KIK41057.1 - 5.8e-05 23.1 10.4 0.00013 22.0 10.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIK41057.1 - 9e-05 22.5 13.4 0.00019 21.5 13.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KIK41057.1 - 0.043 14.3 5.8 0.077 13.5 5.8 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor GDA1_CD39 PF01150.17 KIK41058.1 - 5.1e-91 305.5 0.0 7e-91 305.0 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 KIK41058.1 - 0.25 10.7 0.0 0.39 10.1 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family MFS_1 PF07690.16 KIK41059.1 - 1.3e-23 83.5 35.0 1.4e-19 70.2 11.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK41059.1 - 0.00038 19.5 0.8 0.00038 19.5 0.8 2.2 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK41060.1 - 1.1e-18 67.3 26.6 1.1e-18 67.3 26.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK41060.1 - 0.0042 16.0 0.9 0.0042 16.0 0.9 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter WD40 PF00400.32 KIK41062.1 - 3.3e-08 34.0 0.0 4.3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 WD domain, G-beta repeat Nup160 PF11715.8 KIK41062.1 - 0.17 10.5 0.0 0.17 10.5 0.0 1.0 1 0 0 1 1 1 0 Nucleoporin Nup120/160 ALS_ss_C PF10369.9 KIK41063.1 - 3.3e-18 65.7 0.2 1.2e-16 60.7 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 KIK41063.1 - 1e-13 50.8 0.1 2e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 KIK41063.1 - 8e-08 32.0 0.1 3e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 ACT domain DUF2187 PF09953.9 KIK41063.1 - 0.015 15.3 2.0 0.062 13.3 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2187) zf-C2H2 PF00096.26 KIK41064.1 - 0.0058 17.0 7.0 0.03 14.8 2.8 3.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type PyrI_C PF02748.15 KIK41064.1 - 0.028 14.3 0.3 0.028 14.3 0.3 2.1 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-BED PF02892.15 KIK41064.1 - 0.038 14.0 1.9 0.15 12.1 0.1 2.6 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_4 PF13894.6 KIK41064.1 - 0.05 14.5 2.5 0.05 14.5 2.5 4.1 3 1 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 KIK41064.1 - 0.15 12.7 4.0 0.38 11.4 1.2 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 KIK41064.1 - 0.22 12.0 0.4 0.22 12.0 0.4 3.7 4 1 1 5 5 5 0 Zinc-finger double domain DEAD PF00270.29 KIK41067.1 - 7.3e-20 71.5 0.0 8e-17 61.5 0.0 3.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK41067.1 - 1.6e-13 51.0 0.0 4.3e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK41067.1 - 0.0028 17.7 0.0 0.0048 16.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit WD40 PF00400.32 KIK41069.1 - 0.0015 19.3 0.0 0.0018 19.0 0.0 1.2 1 0 0 1 1 1 1 WD domain, G-beta repeat WD40 PF00400.32 KIK41070.1 - 1.1e-18 67.2 4.7 6.3e-06 26.8 0.5 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41070.1 - 2.4e-07 31.0 0.0 0.041 14.2 0.0 3.6 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK41072.1 - 1.4e-37 127.0 9.6 9e-07 29.5 0.1 9.1 8 1 1 9 9 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41072.1 - 1e-09 38.5 0.1 0.42 10.9 0.0 6.0 2 1 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 KIK41072.1 - 1e-07 32.4 3.7 8e-06 26.3 0.3 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ge1_WD40 PF16529.5 KIK41072.1 - 2.5e-07 30.0 0.1 0.00021 20.4 0.1 3.3 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_1 PF00515.28 KIK41072.1 - 0.00043 20.0 3.8 9.8 6.2 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIK41072.1 - 0.0021 18.7 1.1 3.7 8.6 0.2 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat Nucleoporin_N PF08801.11 KIK41072.1 - 0.036 12.8 0.1 0.64 8.7 0.1 2.4 2 0 0 2 2 2 0 Nup133 N terminal like TPR_2 PF07719.17 KIK41072.1 - 0.049 13.8 4.8 11 6.4 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK41072.1 - 0.11 13.0 1.3 24 5.5 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 KIK41072.1 - 0.14 12.5 0.1 1.6 9.2 0.0 2.5 2 0 0 2 2 2 0 PPR repeat TPR_16 PF13432.6 KIK41072.1 - 0.14 12.9 4.8 55 4.5 3.3 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.32 KIK41073.1 - 2.6e-21 75.5 8.2 0.0002 22.1 0.0 7.0 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41073.1 - 0.00026 21.2 0.0 1.8 8.9 0.0 4.2 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ret2_MD PF18528.1 KIK41073.1 - 0.16 12.3 0.0 0.45 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA editing 3' terminal uridylyl transferase 2 middle domain WD40 PF00400.32 KIK41075.1 - 5.9e-14 52.2 1.2 4.6e-05 24.1 0.1 4.4 4 1 0 4 4 4 3 WD domain, G-beta repeat zf-H2C2_2 PF13465.6 KIK41077.1 - 0.012 16.0 1.2 0.042 14.3 1.2 2.0 1 0 0 1 1 1 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KIK41077.1 - 0.015 15.5 1.8 0.73 10.2 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KIK41077.1 - 0.1 13.5 0.9 0.1 13.5 0.9 2.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KIK41077.1 - 0.27 11.2 2.3 0.41 10.6 0.7 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 KIK41077.1 - 0.35 11.4 5.5 0.17 12.4 1.2 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type F-box PF00646.33 KIK41079.1 - 0.00096 19.0 1.5 0.0015 18.4 0.4 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIK41079.1 - 0.0083 16.0 0.1 0.03 14.2 0.1 2.0 1 0 0 1 1 1 1 F-box-like UCH PF00443.29 KIK41080.1 - 5.6e-57 193.2 0.0 7.8e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIK41080.1 - 7.8e-31 107.8 2.7 2.4e-29 103.0 2.7 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KIK41080.1 - 0.0056 16.2 0.3 0.32 10.4 0.4 2.9 3 0 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase MOSC PF03473.17 KIK41082.1 - 1.8e-21 76.5 0.0 2.9e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KIK41082.1 - 1.9e-15 56.8 0.0 3.1e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Rotamase PF00639.21 KIK41083.1 - 1.6e-21 77.1 0.1 2.4e-21 76.5 0.1 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KIK41083.1 - 4.6e-16 59.4 0.1 6e-16 59.0 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KIK41083.1 - 6.6e-09 35.7 0.3 1.9e-08 34.3 0.1 1.8 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KIK41083.1 - 9.5e-07 29.7 0.0 1.3e-06 29.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain AAA_19 PF13245.6 KIK41083.1 - 0.12 12.7 0.0 0.15 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF4246 PF14033.6 KIK41084.1 - 2.6e-90 303.7 0.0 3.4e-90 303.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) GDP_Man_Dehyd PF16363.5 KIK41085.1 - 3e-41 141.9 0.0 4.1e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIK41085.1 - 2.4e-40 138.5 0.0 3.2e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK41085.1 - 3.7e-11 42.5 0.0 7.1e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KIK41085.1 - 1.1e-09 37.8 0.0 2.4e-09 36.7 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KIK41085.1 - 2.4e-09 36.7 0.0 1.9e-08 33.8 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 KIK41085.1 - 3.1e-07 30.5 0.0 6.4e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KIK41085.1 - 0.00012 21.3 0.0 0.00029 20.1 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KIK41085.1 - 0.0059 16.1 0.1 0.065 12.7 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 KIK41085.1 - 0.0097 15.8 0.0 0.094 12.6 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 KIK41085.1 - 0.03 14.5 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short_C2 PF13561.6 KIK41085.1 - 0.04 13.5 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase efThoc1 PF11957.8 KIK41086.1 - 5.7e-92 308.9 3.0 2e-86 290.7 0.4 2.1 2 0 0 2 2 2 2 THO complex subunit 1 transcription elongation factor UCH PF00443.29 KIK41088.1 - 2e-41 142.2 0.0 7.6e-41 140.3 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 KIK41088.1 - 3.5e-23 81.3 0.6 4.4e-16 58.5 0.1 3.2 3 0 0 3 3 3 2 A repeated domain in UCH-protein UCH_1 PF13423.6 KIK41088.1 - 3.5e-08 33.4 2.4 0.0012 18.6 0.1 2.6 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase NAD_binding_1 PF00175.21 KIK41090.1 - 7.5e-27 94.1 0.0 1.3e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KIK41090.1 - 2.5e-17 63.1 0.0 5.3e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KIK41090.1 - 0.00038 20.6 0.0 0.027 14.6 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DUF4536 PF15055.6 KIK41090.1 - 0.043 14.1 0.3 0.12 12.7 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) DNA_methylase PF00145.17 KIK41090.1 - 0.085 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Shigella_OspC PF06128.11 KIK41090.1 - 0.097 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Shigella flexneri OspC protein DUF4101 PF13355.6 KIK41090.1 - 0.19 12.1 0.1 0.34 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4101) Pkinase PF00069.25 KIK41091.1 - 1.4e-65 221.3 0.0 1.7e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK41091.1 - 3.6e-31 108.4 0.0 4.6e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK41091.1 - 6.6e-06 25.3 0.0 9.4e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KIK41091.1 - 0.00057 19.3 0.0 0.0015 17.9 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK41091.1 - 0.00097 19.1 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK41091.1 - 0.0083 15.5 0.0 0.039 13.3 0.0 1.9 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 KIK41091.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KIK41091.1 - 0.032 13.8 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DNMT1-RFD PF12047.8 KIK41092.1 - 0.11 12.5 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain EBP PF05241.12 KIK41093.1 - 0.4 10.1 12.0 0.8 9.1 12.0 1.6 1 1 0 1 1 1 0 Emopamil binding protein zf-C2H2 PF00096.26 KIK41094.1 - 0.053 14.0 3.6 0.13 12.8 3.6 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Bestrophin PF01062.21 KIK41096.1 - 1.3e-35 123.3 0.2 1.3e-24 87.1 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel HGTP_anticodon PF03129.20 KIK41097.1 - 4.1e-22 78.1 0.2 1.3e-21 76.6 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KIK41097.1 - 1.1e-10 41.7 0.0 2.7e-10 40.5 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) SICA_alpha PF12887.7 KIK41097.1 - 0.12 12.3 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 SICA extracellular alpha domain F-box PF00646.33 KIK41099.1 - 1e-05 25.3 0.6 2.5e-05 24.0 0.6 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK41099.1 - 0.00034 20.4 0.5 0.00071 19.4 0.5 1.5 1 0 0 1 1 1 1 F-box-like UCH PF00443.29 KIK41103.1 - 5.2e-41 140.8 0.0 7.9e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KIK41103.1 - 1.4e-24 86.2 9.9 3.3e-21 75.4 1.7 3.1 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 KIK41103.1 - 4.3e-24 84.0 0.4 3e-12 46.2 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 KIK41103.1 - 1.6e-22 79.0 5.1 3.4e-21 74.8 0.8 2.6 2 0 0 2 2 2 2 Variant UBP zinc finger UCH_1 PF13423.6 KIK41103.1 - 2.8e-14 53.5 0.0 1.5e-12 47.8 0.0 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Eapp_C PF10238.9 KIK41103.1 - 0.023 14.8 0.9 0.094 12.8 0.9 2.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein zf-C2HE PF16278.5 KIK41103.1 - 0.03 14.8 1.0 12 6.5 0.1 2.8 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger UBA_4 PF14555.6 KIK41103.1 - 0.061 13.2 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 UBA-like domain Acetyltransf_8 PF13523.6 KIK41104.1 - 6.1e-37 126.5 0.2 9.8e-37 125.9 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIK41104.1 - 0.00037 21.2 0.0 0.00073 20.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HSP70 PF00012.20 KIK41105.1 - 1.4e-63 215.0 2.1 9e-47 159.6 0.1 2.4 2 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 KIK41105.1 - 2.3e-11 43.1 0.1 2.8e-10 39.5 0.1 2.2 1 1 0 1 1 1 1 MreB/Mbl protein U3_snoRNA_assoc PF08297.11 KIK41105.1 - 0.049 14.3 0.9 0.049 14.3 0.9 1.9 2 0 0 2 2 2 0 U3 snoRNA associated PilM_2 PF11104.8 KIK41105.1 - 0.064 12.3 0.0 0.19 10.7 0.0 1.7 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Phage_TAC_2 PF06894.11 KIK41105.1 - 0.069 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G dCMP_cyt_deam_1 PF00383.23 KIK41106.1 - 5.5e-16 58.3 0.0 1.2e-15 57.2 0.0 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KIK41106.1 - 6.5e-14 51.9 0.0 9.5e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC2 PF18772.1 KIK41106.1 - 0.0014 18.7 0.0 0.03 14.4 0.0 2.0 1 1 0 1 1 1 1 APOBEC2 SNAD4 PF18750.1 KIK41106.1 - 0.0031 17.6 0.0 0.0072 16.4 0.0 1.6 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 KIK41106.1 - 0.0035 17.5 0.1 0.063 13.4 0.1 2.0 1 1 0 1 1 1 1 Novel AID APOBEC clade 1 Bd3614-deam PF14439.6 KIK41106.1 - 0.02 14.9 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase NAD2 PF18782.1 KIK41106.1 - 0.11 12.5 0.0 0.35 10.9 0.0 1.7 2 0 0 2 2 2 0 Novel AID APOBEC clade 2 APOBEC_N PF08210.11 KIK41106.1 - 0.13 12.2 0.1 1 9.2 0.0 2.0 1 1 1 2 2 2 0 APOBEC-like N-terminal domain Oxysterol_BP PF01237.18 KIK41107.1 - 1.5e-133 445.3 0.0 2.5e-133 444.5 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_2 PF12796.7 KIK41107.1 - 6.3e-13 49.1 0.0 2.1e-10 41.0 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIK41107.1 - 6.4e-13 48.6 2.1 2.2e-06 27.8 0.0 3.6 2 1 0 3 3 3 2 Ankyrin repeats (many copies) PH PF00169.29 KIK41107.1 - 4.5e-11 43.2 0.0 1e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 KIK41107.1 - 7.1e-11 42.4 0.4 2.7e-05 24.6 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KIK41107.1 - 3.7e-10 39.8 3.0 0.0013 19.1 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KIK41107.1 - 5.6e-10 38.6 0.7 0.029 14.9 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat PH_8 PF15409.6 KIK41107.1 - 1.4e-06 28.5 0.0 4.3e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KIK41107.1 - 2.4e-05 24.7 0.1 5.8e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain AA_permease PF00324.21 KIK41108.1 - 1e-117 393.7 34.9 1.2e-117 393.4 34.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK41108.1 - 3.4e-33 115.1 39.8 4.2e-33 114.8 39.8 1.0 1 0 0 1 1 1 1 Amino acid permease PRA1 PF03208.19 KIK41109.1 - 0.091 12.4 2.2 0.12 12.0 2.2 1.3 1 0 0 1 1 1 0 PRA1 family protein Mem_trans PF03547.18 KIK41111.1 - 1.4e-11 43.5 10.2 5e-07 28.5 3.1 2.2 2 0 0 2 2 2 2 Membrane transport protein Mem_trans PF03547.18 KIK41114.1 - 1.3e-17 63.2 18.9 2.3e-16 59.2 18.9 2.0 1 1 0 1 1 1 1 Membrane transport protein Gpr1_Fun34_YaaH PF01184.19 KIK41115.1 - 9.5e-74 247.5 18.7 1.1e-73 247.2 18.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family NAP PF00956.18 KIK41116.1 - 8.9e-87 290.7 2.1 1.2e-86 290.3 2.1 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) TauD PF02668.16 KIK41117.1 - 1.3e-63 215.3 0.5 2e-63 214.7 0.5 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family BPL_LplA_LipB PF03099.19 KIK41119.1 - 2.9e-15 56.3 0.0 5.2e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_N PF09825.9 KIK41119.1 - 1.4e-10 40.9 1.0 0.00012 21.3 0.9 2.9 2 1 0 2 2 2 2 Biotin-protein ligase, N terminal BPL_C PF02237.17 KIK41119.1 - 0.033 14.1 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain DDHD PF02862.17 KIK41121.1 - 0.078 13.1 0.3 0.092 12.9 0.3 1.1 1 0 0 1 1 1 0 DDHD domain CPSF100_C PF13299.6 KIK41121.1 - 0.11 12.7 2.4 0.16 12.1 2.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal zf-CCHC PF00098.23 KIK41122.1 - 0.0029 17.6 3.0 0.0055 16.7 3.0 1.5 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 KIK41123.1 - 0.00059 20.3 0.0 0.0012 19.4 0.0 1.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIK41123.1 - 0.00073 20.1 0.0 0.033 14.8 0.0 2.1 1 1 1 2 2 2 2 Aspartyl protease Peptidase_A2B PF12384.8 KIK41123.1 - 0.032 13.8 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 Ty3 transposon peptidase RT_RNaseH_2 PF17919.1 KIK41125.1 - 1.3e-09 38.0 0.0 1.5e-09 37.8 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PP2C_2 PF13672.6 KIK41125.1 - 0.0016 18.1 0.0 0.0016 18.1 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C RT_RNaseH PF17917.1 KIK41125.1 - 0.054 13.8 0.0 0.086 13.1 0.0 1.3 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Pox_Ag35 PF03286.14 KIK41126.1 - 0.072 12.9 7.9 0.11 12.3 7.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.14 KIK41126.1 - 3.1 6.0 8.5 3 6.0 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Ifi-6-16 PF06140.13 KIK41127.1 - 9.5e-06 25.4 0.0 1.9e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Interferon-induced 6-16 family Ifi-6-16 PF06140.13 KIK41128.1 - 1.4e-05 24.9 2.2 1.7e-05 24.7 0.5 2.0 2 0 0 2 2 2 1 Interferon-induced 6-16 family CGI-121 PF08617.10 KIK41131.1 - 1.6e-48 164.9 0.0 1.8e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Thioredoxin PF00085.20 KIK41132.1 - 1.5e-45 153.4 0.2 2.1e-24 85.5 0.1 3.0 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KIK41132.1 - 1.4e-18 67.5 0.0 1.7e-12 47.6 0.0 3.7 1 1 2 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KIK41132.1 - 6.9e-07 29.5 2.0 0.0028 17.9 0.0 3.9 4 0 0 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 KIK41132.1 - 1e-06 28.4 5.7 0.14 11.5 0.0 4.1 3 1 0 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 KIK41132.1 - 0.0015 18.5 0.1 0.06 13.4 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin domain UL11 PF11094.8 KIK41132.1 - 0.036 13.9 0.1 0.036 13.9 0.1 2.0 2 0 0 2 2 2 0 Membrane-associated tegument protein Thioredoxin_2 PF13098.6 KIK41132.1 - 0.084 13.3 1.5 1.8 9.0 0.2 3.0 2 1 0 2 2 2 0 Thioredoxin-like domain PPR_2 PF13041.6 KIK41134.1 - 4.5e-50 167.6 0.2 8.5e-10 38.7 0.0 14.7 11 3 5 16 16 16 9 PPR repeat family PPR PF01535.20 KIK41134.1 - 3.9e-41 136.4 8.7 0.00072 19.6 0.0 14.9 15 1 0 15 15 15 7 PPR repeat PPR_3 PF13812.6 KIK41134.1 - 1.9e-30 104.7 0.0 8.4e-09 35.4 0.0 10.9 7 3 5 12 12 12 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 KIK41134.1 - 1.1e-28 98.6 0.1 1.4e-06 27.8 0.0 11.3 11 0 0 11 11 11 5 PPR repeat PPR_long PF17177.4 KIK41134.1 - 2.3e-14 53.3 9.6 4e-10 39.4 0.0 6.0 3 2 4 7 7 7 3 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 KIK41134.1 - 1.2e-05 25.7 0.5 2.5 8.7 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK41134.1 - 0.0011 19.7 17.0 4.6 8.3 0.0 8.2 10 0 0 10 10 7 1 Tetratricopeptide repeat ATP13 PF12921.7 KIK41134.1 - 0.0084 16.0 0.3 2.6 7.9 0.0 4.6 4 1 1 5 5 5 1 Mitochondrial ATPase expression TPR_6 PF13174.6 KIK41134.1 - 0.021 15.4 8.3 32 5.5 0.1 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIK41134.1 - 0.038 14.6 7.7 2.6 8.9 0.0 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat Clathrin PF00637.20 KIK41134.1 - 0.28 11.1 1.1 13 5.6 0.0 3.4 3 0 0 3 3 3 0 Region in Clathrin and VPS Coilin_N PF15862.5 KIK41135.1 - 5.2e-09 36.0 0.3 1.3e-08 34.7 0.3 1.6 1 0 0 1 1 1 1 Coilin N-terminus AF-4 PF05110.13 KIK41135.1 - 0.00026 19.2 19.0 0.00033 18.9 19.0 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein FAM199X PF15814.5 KIK41135.1 - 0.00068 18.8 7.4 0.0011 18.1 7.4 1.4 1 0 0 1 1 1 1 Protein family FAM199X p6 PF17548.2 KIK41135.1 - 0.013 15.4 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Histone-like Protein p6 Apt1 PF10351.9 KIK41135.1 - 0.16 10.8 8.1 0.21 10.4 8.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 KIK41135.1 - 0.3 9.3 3.1 0.44 8.8 3.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4667 PF15700.5 KIK41135.1 - 0.76 9.8 16.8 0.14 12.2 12.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Cwf_Cwc_15 PF04889.12 KIK41135.1 - 0.99 9.1 7.4 1.8 8.3 7.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Secretin_N_2 PF07655.13 KIK41135.1 - 1.8 9.1 16.8 5.6 7.6 16.8 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain PI3K_1B_p101 PF10486.9 KIK41135.1 - 3.2 5.4 7.2 4.7 4.9 7.2 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Sec63 PF02889.16 KIK41136.1 - 4.9e-16 58.7 0.0 1.1e-15 57.5 0.0 1.6 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 KIK41136.1 - 8.9e-14 51.4 0.1 2e-13 50.2 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-binding PF00249.31 KIK41136.1 - 0.053 13.7 0.1 20 5.5 0.0 3.0 3 0 0 3 3 3 0 Myb-like DNA-binding domain WGG PF10273.9 KIK41137.1 - 7.4e-27 93.8 0.0 1.4e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 eIF3g PF12353.8 KIK41138.1 - 1.3e-42 145.1 2.7 1.9e-42 144.6 2.7 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KIK41138.1 - 1.2e-17 63.5 0.0 2.2e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIK41138.1 - 0.072 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif mRNA_cap_C PF03919.15 KIK41138.1 - 0.075 13.7 0.5 0.14 12.8 0.5 1.4 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Ribosomal_60s PF00428.19 KIK41139.1 - 1.2e-26 93.1 10.6 1.6e-26 92.7 10.6 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 KIK41139.1 - 0.24 9.8 0.5 0.33 9.4 0.5 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein RNA_pol_Rpb1_1 PF04997.12 KIK41140.1 - 3.8e-85 286.0 0.0 6.1e-85 285.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KIK41140.1 - 3.1e-82 276.0 0.2 4.5e-82 275.5 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KIK41140.1 - 1.2e-71 240.3 0.0 2.3e-71 239.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KIK41140.1 - 8.3e-39 133.0 0.1 2.1e-37 128.5 0.0 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KIK41140.1 - 6.8e-33 112.8 0.0 1.4e-32 111.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 zinc_ribbon_15 PF17032.5 KIK41140.1 - 0.51 11.1 3.4 1.4 9.8 3.4 1.8 1 0 0 1 1 1 0 zinc-ribbon family Proteasome PF00227.26 KIK41141.1 - 3.2e-44 150.7 0.7 1.4e-43 148.7 0.7 1.8 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIK41141.1 - 1.1e-14 53.7 0.3 2.1e-14 52.9 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Tho1_MOS11_C PF18592.1 KIK41141.1 - 0.072 12.9 1.2 0.13 12.1 1.2 1.4 1 0 0 1 1 1 0 Tho1/MOS11 C-terminal domain S36_mt PF10937.8 KIK41142.1 - 1.6e-06 29.7 3.3 0.013 17.0 0.9 2.5 1 1 1 2 2 2 2 Ribosomal protein S36, mitochondrial Ric8 PF10165.9 KIK41143.1 - 1.2e-119 400.4 0.0 1.4e-119 400.1 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn RRM_1 PF00076.22 KIK41144.1 - 5.9e-41 138.1 0.0 1.7e-19 69.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK41144.1 - 2.8e-05 24.2 0.0 0.35 11.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 KIK41144.1 - 0.00069 19.2 0.0 0.0019 17.8 0.0 1.8 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KIK41144.1 - 0.0051 16.8 0.0 0.019 15.0 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KIK41144.1 - 0.12 12.2 0.0 3.5 7.6 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif GDI PF00996.18 KIK41145.1 - 3.8e-45 154.2 0.0 6.8e-45 153.4 0.0 1.4 2 0 0 2 2 2 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KIK41145.1 - 0.023 14.9 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pkinase PF00069.25 KIK41146.1 - 4.8e-17 62.2 0.0 6.6e-17 61.7 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK41146.1 - 4.1e-08 32.8 0.0 6.6e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK41146.1 - 2.8e-05 23.1 0.1 3.7e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KIK41146.1 - 0.0065 16.1 0.0 0.0091 15.6 0.0 1.2 1 0 0 1 1 1 1 RIO1 family VPS53_C PF16854.5 KIK41146.1 - 0.04 13.8 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus APH PF01636.23 KIK41146.1 - 0.12 12.2 0.1 1.1 9.1 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Dimer_Tnp_hAT PF05699.14 KIK41148.1 - 6.7e-10 38.6 0.1 1.3e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RNase_P_pop3 PF08228.11 KIK41148.1 - 0.0092 16.0 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 RNase P subunit Pop3 Gasdermin PF04598.12 KIK41152.1 - 0.23 10.9 0.0 5.1 6.5 0.0 2.2 1 1 1 2 2 2 0 Gasdermin pore forming domain DNA_pol_B_palm PF14792.6 KIK41153.1 - 1.8e-26 92.6 0.0 4.3e-26 91.4 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 KIK41153.1 - 3.6e-22 77.9 0.2 5.1e-20 71.0 0.1 2.7 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 KIK41153.1 - 7.5e-20 70.9 0.0 2e-19 69.5 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 KIK41153.1 - 1e-16 61.0 0.3 3e-16 59.5 0.2 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain BRCT PF00533.26 KIK41153.1 - 2.3e-05 24.7 0.0 8.6e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KIK41153.1 - 0.00039 20.7 0.0 0.00093 19.4 0.0 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain HHH_5 PF14520.6 KIK41153.1 - 0.0015 19.1 0.0 0.083 13.5 0.0 2.7 1 1 1 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 KIK41153.1 - 0.022 14.6 0.8 0.049 13.5 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif BRCT_2 PF16589.5 KIK41153.1 - 0.12 12.8 0.0 0.4 11.1 0.0 1.9 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Methyltransf_23 PF13489.6 KIK41154.1 - 1.1e-15 57.8 0.0 1.8e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK41154.1 - 1e-11 45.3 0.0 4.4e-11 43.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK41154.1 - 4.3e-10 39.6 0.0 1.4e-09 37.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK41154.1 - 5.8e-08 33.3 0.0 1.3e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK41154.1 - 1e-05 26.2 0.0 3.3e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 KIK41154.1 - 2.2e-05 24.6 0.0 3.6e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KIK41154.1 - 4.4e-05 22.9 0.0 0.00041 19.8 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KIK41154.1 - 0.00061 19.3 0.0 0.0036 16.8 0.0 2.1 1 1 1 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.15 KIK41154.1 - 0.0016 18.4 0.0 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 KIK41154.1 - 0.024 14.2 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CheR PF01739.18 KIK41154.1 - 0.027 14.0 0.0 0.095 12.2 0.0 1.8 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Peptidase_M16 PF00675.20 KIK41155.1 - 9.8e-22 77.5 0.1 1.7e-21 76.8 0.1 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KIK41155.1 - 2e-05 24.7 0.0 0.00018 21.6 0.0 2.3 1 1 0 1 1 1 1 Peptidase M16 inactive domain PhoLip_ATPase_C PF16212.5 KIK41156.1 - 2.5e-52 178.1 23.4 2.5e-52 178.1 23.4 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 KIK41156.1 - 6.2e-16 59.3 0.4 2.9e-10 40.8 0.3 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 KIK41156.1 - 2.1e-14 52.9 6.8 5.1e-14 51.7 6.8 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 KIK41156.1 - 3.5e-13 49.5 0.1 3.5e-13 49.5 0.1 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KIK41156.1 - 2.4e-08 33.9 0.0 1.6e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KIK41156.1 - 0.0011 18.7 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NST1 PF13945.6 KIK41157.1 - 2.7e-56 190.7 1.9 2.7e-56 190.7 1.9 4.9 4 2 1 5 5 5 1 Salt tolerance down-regulator TFIIA PF03153.13 KIK41157.1 - 0.00013 22.1 9.4 0.00013 22.1 9.4 4.1 2 1 2 4 4 4 1 Transcription factor IIA, alpha/beta subunit Glyco_hydr_30_2 PF14587.6 KIK41159.1 - 0.21 11.1 0.9 0.26 10.9 0.9 1.1 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 dCMP_cyt_deam_1 PF00383.23 KIK41160.1 - 8.1e-09 35.3 0.0 1.1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KIK41160.1 - 0.0015 18.3 0.1 0.0021 17.8 0.1 1.2 1 0 0 1 1 1 1 MafB19-like deaminase DUF5571 PF17732.1 KIK41160.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5571) PEMT PF04191.13 KIK41161.1 - 2.7e-53 178.8 10.5 1.3e-30 105.9 1.9 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 KIK41161.1 - 0.015 15.1 0.1 0.031 14.1 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 KIK41161.1 - 0.035 14.6 0.0 0.11 13.0 0.1 1.8 2 0 0 2 2 2 0 SKICH domain ApoLp-III PF07464.11 KIK41161.1 - 0.05 13.7 0.1 0.086 12.9 0.1 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Tox-MPTase5 PF15641.6 KIK41161.1 - 0.1 12.6 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Metallopeptidase toxin 5 Aminotran_3 PF00202.21 KIK41162.1 - 1.3e-116 389.6 0.0 1.6e-116 389.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DHHC PF01529.20 KIK41163.1 - 2.9e-34 118.1 20.2 5.2e-34 117.2 8.2 2.3 2 0 0 2 2 2 2 DHHC palmitoyltransferase LIDHydrolase PF10230.9 KIK41163.1 - 0.11 12.0 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase SieB PF14163.6 KIK41163.1 - 0.78 9.2 7.0 0.74 9.3 4.0 2.2 1 1 1 2 2 2 0 Super-infection exclusion protein B Cullin_binding PF03556.15 KIK41164.1 - 5e-34 117.3 0.3 8e-34 116.7 0.3 1.3 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 KIK41164.1 - 3.6e-11 42.7 0.0 7.7e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain MPP6 PF10175.9 KIK41167.1 - 4.5e-05 24.0 5.1 4.5e-05 24.0 5.1 2.5 1 1 1 2 2 2 1 M-phase phosphoprotein 6 PseudoU_synth_1 PF01416.20 KIK41169.1 - 4.3e-24 85.1 0.0 3.9e-23 82.0 0.0 2.5 2 1 0 2 2 2 1 tRNA pseudouridine synthase RNA_pol_3_Rpc31 PF11705.8 KIK41170.1 - 0.15 12.3 6.1 0.053 13.8 2.2 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Rox3 PF08633.10 KIK41170.1 - 0.19 12.0 5.3 2.9 8.1 0.2 2.3 2 0 0 2 2 2 0 Rox3 mediator complex subunit WD40 PF00400.32 KIK41171.1 - 8e-47 156.3 28.2 3.1e-10 40.5 1.2 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41171.1 - 5.6e-21 74.6 3.6 0.00028 21.1 0.1 5.4 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK41171.1 - 1.5e-06 27.5 0.1 0.15 11.0 0.0 4.6 2 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK41171.1 - 1.8e-06 26.9 3.4 0.11 11.1 0.0 4.5 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK41171.1 - 0.0059 16.0 3.2 0.2 11.0 0.1 3.9 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KIK41171.1 - 0.012 15.5 0.4 58 3.8 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 KIK41171.1 - 0.013 14.3 0.4 7.4 5.2 0.1 3.2 2 2 1 3 3 3 0 Nup133 N terminal like Cytochrom_D1 PF02239.16 KIK41171.1 - 0.019 13.5 0.6 2.4 6.6 0.1 2.8 1 1 2 3 3 3 0 Cytochrome D1 heme domain WD40_like PF17005.5 KIK41171.1 - 0.087 12.1 0.0 9.9 5.4 0.0 2.8 2 1 1 3 3 3 0 WD40-like domain DUF5570 PF17731.1 KIK41171.1 - 0.15 12.1 10.3 1.5 8.9 0.0 3.7 3 1 1 4 4 4 0 Family of unknown function (DUF5570) Arf PF00025.21 KIK41173.1 - 3.8e-35 120.9 0.0 1.3e-34 119.2 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KIK41173.1 - 2.4e-11 43.4 0.0 1.9e-06 27.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KIK41173.1 - 1.9e-08 34.5 0.0 2.9e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KIK41173.1 - 1.9e-06 27.4 0.0 3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KIK41173.1 - 8.7e-06 25.3 0.0 1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIK41173.1 - 3.2e-05 24.0 0.0 5.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KIK41173.1 - 4.7e-05 23.0 0.0 5.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 KIK41173.1 - 8.4e-05 22.2 0.0 0.023 14.2 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KIK41173.1 - 0.00058 20.1 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KIK41173.1 - 0.0024 18.4 0.8 0.0029 18.1 0.8 1.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KIK41173.1 - 0.0027 18.2 0.5 0.0046 17.5 0.5 1.8 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KIK41173.1 - 0.0031 17.4 0.0 0.7 9.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 KIK41173.1 - 0.0078 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KIK41173.1 - 0.027 14.2 0.9 0.044 13.5 0.1 1.8 2 0 0 2 2 2 0 Thymidylate kinase NB-ARC PF00931.22 KIK41173.1 - 0.031 13.5 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 KIK41173.1 - 0.032 14.6 0.1 0.039 14.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KIK41173.1 - 0.032 14.0 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.22 KIK41173.1 - 0.044 13.4 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TniB PF05621.11 KIK41173.1 - 0.045 13.2 0.0 0.085 12.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein cobW PF02492.19 KIK41173.1 - 0.06 12.9 0.0 0.3 10.7 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KIK41173.1 - 0.065 13.4 0.4 0.13 12.5 0.4 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KIK41173.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KIK41173.1 - 0.089 13.3 0.2 0.15 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KIK41173.1 - 0.12 11.6 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain MobB PF03205.14 KIK41173.1 - 0.18 11.7 0.2 0.51 10.2 0.1 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATPase_2 PF01637.18 KIK41173.1 - 0.21 11.5 0.1 0.36 10.7 0.1 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Bac_rhodopsin PF01036.18 KIK41174.1 - 5.6 6.5 10.8 0.033 13.8 1.8 1.8 3 0 0 3 3 3 0 Bacteriorhodopsin-like protein Fes1 PF08609.10 KIK41175.1 - 1.3e-22 80.5 1.2 4.2e-22 78.8 0.2 2.2 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 SIL1 PF16782.5 KIK41175.1 - 0.0031 16.8 0.0 0.0045 16.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 HEAT_2 PF13646.6 KIK41175.1 - 0.0058 17.0 1.3 0.014 15.8 0.1 2.2 3 0 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 KIK41175.1 - 0.046 14.2 0.9 2.3 8.8 0.1 2.9 2 0 0 2 2 2 0 HEAT-like repeat HEAT PF02985.22 KIK41175.1 - 0.053 13.8 1.5 5.3 7.6 0.1 3.5 3 0 0 3 3 3 0 HEAT repeat TfoX_C PF04994.13 KIK41175.1 - 0.1 12.7 0.1 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 TfoX C-terminal domain E_Pc_C PF06752.12 KIK41175.1 - 7.6 6.6 10.5 14 5.7 6.8 2.2 1 1 1 2 2 2 0 Enhancer of Polycomb C-terminus ICMT PF04140.14 KIK41176.1 - 1.9e-13 50.6 0.5 1.2e-12 48.1 0.1 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK41176.1 - 9.8e-10 38.8 4.8 1.3e-09 38.4 1.9 2.3 2 1 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIK41176.1 - 2.1e-07 30.1 0.1 2.8e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KIK41176.1 - 0.0049 16.4 0.1 0.0077 15.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DoxX_2 PF13564.6 KIK41176.1 - 0.011 15.9 0.0 0.079 13.1 0.0 2.2 2 0 0 2 2 2 0 DoxX-like family DUF3955 PF13127.6 KIK41176.1 - 0.037 13.9 0.4 0.13 12.1 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3955) UIM PF02809.20 KIK41176.1 - 0.39 10.7 1.2 1.1 9.4 1.2 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Oxidored_FMN PF00724.20 KIK41178.1 - 1e-65 222.3 0.0 1.2e-65 222.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Ank_2 PF12796.7 KIK41179.1 - 3.6e-65 216.5 9.2 2.9e-07 31.0 0.0 12.4 9 2 0 12 12 11 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK41179.1 - 8.8e-63 207.9 18.1 2.6e-05 24.7 0.1 17.1 11 7 7 18 18 18 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIK41179.1 - 1.4e-49 165.5 18.6 1.9e-05 24.9 0.0 16.2 16 1 1 17 17 16 10 Ankyrin repeats (many copies) Ank PF00023.30 KIK41179.1 - 3.2e-37 125.4 40.0 7.6e-05 23.0 0.5 20.7 17 4 2 19 19 17 6 Ankyrin repeat Ank_3 PF13606.6 KIK41179.1 - 8.3e-37 121.0 21.7 2.2e-05 24.4 0.0 19.0 18 1 1 19 19 16 5 Ankyrin repeat NACHT PF05729.12 KIK41179.1 - 4.4e-07 30.0 0.1 1.5e-06 28.2 0.1 2.0 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK41179.1 - 6e-05 23.5 0.0 0.00029 21.3 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain Helo_like_N PF17111.5 KIK41179.1 - 0.00024 20.5 3.1 0.00058 19.3 3.1 1.6 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 KIK41179.1 - 0.0016 18.7 0.0 0.0098 16.2 0.0 2.4 2 0 0 2 2 1 1 AAA domain DUF2075 PF09848.9 KIK41179.1 - 0.0057 15.9 0.7 0.0094 15.2 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 KIK41179.1 - 0.017 14.3 0.0 0.27 10.4 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 KIK41179.1 - 0.06 13.8 0.0 0.24 11.8 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KIK41179.1 - 0.074 12.8 1.8 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KIK41179.1 - 0.081 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase CdvA PF18822.1 KIK41179.1 - 0.082 12.7 3.3 0.27 11.1 3.3 1.8 1 0 0 1 1 1 0 CdvA-like coiled-coil domain RNA_helicase PF00910.22 KIK41179.1 - 0.086 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KIK41179.1 - 0.086 12.9 0.0 0.39 10.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain CLP1_P PF16575.5 KIK41179.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF1664 PF07889.12 KIK41179.1 - 0.25 11.4 7.0 4.5 7.3 3.0 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) Phage_Mu_Gam PF07352.12 KIK41179.1 - 0.4 10.6 4.4 0.84 9.5 4.4 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Apolipoprotein PF01442.18 KIK41179.1 - 0.58 10.0 6.2 0.46 10.3 3.5 1.9 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain CheZ PF04344.13 KIK41179.1 - 1.5 8.7 8.1 0.5 10.2 3.7 2.3 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ Muted PF14942.6 KIK41179.1 - 2.3 8.6 9.7 0.46 10.8 4.2 2.4 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF883 PF05957.13 KIK41179.1 - 3 8.5 4.3 2.7 8.7 1.2 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Prominin PF05478.11 KIK41179.1 - 4.1 5.3 6.4 7.6 4.3 6.4 1.4 1 0 0 1 1 1 0 Prominin Phasin PF05597.11 KIK41179.1 - 4.9 7.2 6.3 15 5.6 6.3 1.8 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Baculo_PEP_C PF04513.12 KIK41179.1 - 6.5 6.8 13.0 1.5 8.9 2.0 3.3 4 0 0 4 4 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 KIK41179.1 - 9.3 6.9 13.1 18 6.0 7.0 3.4 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF3983 PF13137.6 KIK41181.1 - 0.18 11.6 1.7 0.49 10.3 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) WW PF00397.26 KIK41186.1 - 0.035 14.2 0.0 0.081 13.0 0.0 1.6 1 0 0 1 1 1 0 WW domain Apolipoprotein PF01442.18 KIK41187.1 - 0.08 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain WD40 PF00400.32 KIK41189.1 - 2.6e-28 97.7 5.7 7.6e-07 29.7 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41189.1 - 1.2e-09 38.4 0.5 0.044 14.1 0.0 5.0 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK41189.1 - 0.00059 18.9 0.0 0.084 11.8 0.0 2.8 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KIK41191.1 - 3.1e-33 113.3 14.0 4e-08 33.8 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41191.1 - 1e-09 38.5 1.3 0.28 11.5 0.0 5.2 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK41191.1 - 0.001 18.1 0.0 3.7 6.4 0.0 3.4 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK41191.1 - 0.066 13.2 0.1 3.7 7.6 0.0 3.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Kin17_mid PF10357.9 KIK41192.1 - 5.1e-49 165.4 1.1 7.8e-49 164.8 1.1 1.3 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 KIK41192.1 - 0.00017 21.9 4.8 0.00038 20.8 4.8 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIK41192.1 - 0.015 15.5 3.9 0.031 14.6 3.9 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KIK41192.1 - 0.038 14.3 0.8 0.038 14.3 0.8 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF2407_C PF13373.6 KIK41193.1 - 1.3e-21 77.2 8.1 1.5e-19 70.6 8.1 3.1 1 1 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 KIK41193.1 - 5.1e-18 65.5 0.1 9.8e-18 64.6 0.1 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KIK41193.1 - 3.4e-05 23.5 0.0 0.00015 21.4 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family AI-2E_transport PF01594.16 KIK41193.1 - 0.019 14.2 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 AI-2E family transporter Rad60-SLD_2 PF13881.6 KIK41193.1 - 0.021 14.9 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like VIT1 PF01988.19 KIK41193.1 - 0.038 13.8 0.0 0.073 12.9 0.0 1.4 1 1 0 1 1 1 0 VIT family UPF0052 PF01933.18 KIK41195.1 - 0.093 12.0 0.4 3.3 6.9 0.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0052 YwcE PF17368.2 KIK41195.1 - 0.14 12.9 0.3 3.1 8.5 0.7 2.1 1 1 1 2 2 2 0 Spore morphogenesis and germination YwcE DUF805 PF05656.14 KIK41197.1 - 7.4 7.0 8.5 30 5.1 8.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF805) IBN_N PF03810.19 KIK41199.1 - 1.2e-08 34.7 0.0 1.6e-07 31.2 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain RIX1 PF08167.12 KIK41199.1 - 0.00047 19.9 0.5 0.015 15.1 0.0 2.8 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Xpo1 PF08389.12 KIK41199.1 - 0.04 14.0 0.0 0.19 11.8 0.0 2.4 1 0 0 1 1 1 0 Exportin 1-like protein DUF4707 PF15806.5 KIK41199.1 - 0.11 11.4 0.3 0.21 10.5 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4707) WD40 PF00400.32 KIK41202.1 - 3.9e-33 112.9 11.8 9.7e-08 32.6 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41202.1 - 2.1e-12 47.2 1.2 0.0038 17.5 0.0 5.0 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK41202.1 - 0.00024 20.2 0.0 0.78 8.6 0.0 3.2 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK41202.1 - 0.11 11.8 0.3 28 3.9 0.1 3.0 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal WD40 PF00400.32 KIK41204.1 - 6.7e-21 74.2 11.4 2.1e-05 25.2 0.4 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41204.1 - 5.9e-06 26.5 0.1 0.036 14.4 0.0 3.5 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Toxin_23 PF08093.11 KIK41204.1 - 0.071 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Magi 5 toxic peptide family COG2 PF06148.11 KIK41208.1 - 0.012 15.7 1.9 0.013 15.6 1.9 1.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Med21 PF11221.8 KIK41208.1 - 0.065 13.5 3.6 0.07 13.4 3.6 1.1 1 0 0 1 1 1 0 Subunit 21 of Mediator complex YjgF_endoribonc PF14588.6 KIK41208.1 - 0.17 12.0 0.0 0.18 12.0 0.0 1.0 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease Phage_integrase PF00589.22 KIK41209.1 - 0.005 16.6 0.0 0.019 14.8 0.0 1.9 1 1 0 1 1 1 1 Phage integrase family zf-CCHC PF00098.23 KIK41210.1 - 1.8 8.8 5.7 0.92 9.7 1.9 2.3 2 0 0 2 2 2 0 Zinc knuckle Pkinase PF00069.25 KIK41211.1 - 2.9e-07 30.1 0.0 1.4e-05 24.6 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK41211.1 - 0.0011 18.3 0.0 0.012 15.0 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Abhydrolase_3 PF07859.13 KIK41212.1 - 9.5e-22 77.9 0.2 2.2e-21 76.7 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK41212.1 - 2.9e-09 36.3 0.0 4.1e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KIK41212.1 - 0.0044 16.5 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Lipase_3 PF01764.25 KIK41212.1 - 0.18 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Nup35_RRM PF05172.13 KIK41213.1 - 9.2e-07 28.8 0.0 7.9e-06 25.8 0.0 2.2 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KIK41213.1 - 0.016 15.2 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF1640 PF07798.11 KIK41214.1 - 6.5e-61 205.4 11.1 7.9e-61 205.1 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HALZ PF02183.18 KIK41214.1 - 0.056 13.7 2.9 0.19 12.0 2.9 2.0 1 1 0 1 1 1 0 Homeobox associated leucine zipper DUF5082 PF16888.5 KIK41214.1 - 0.1 12.9 7.5 0.82 10.0 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Rep_2 PF01719.17 KIK41214.1 - 0.12 12.2 1.3 0.35 10.7 0.6 2.0 2 1 0 2 2 2 0 Plasmid replication protein CCDC23 PF15674.5 KIK41214.1 - 0.39 10.7 0.2 0.39 10.7 0.2 2.7 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 23 Trimer_CC PF08954.11 KIK41214.1 - 0.4 10.3 5.0 0.14 11.7 0.5 2.4 2 0 0 2 2 2 0 Trimerisation motif Phage_GP20 PF06810.11 KIK41214.1 - 0.53 10.1 10.3 1.2 8.9 10.3 1.5 1 1 0 1 1 1 0 Phage minor structural protein GP20 Fib_alpha PF08702.10 KIK41214.1 - 4.5 7.4 13.2 6.2 7.0 0.5 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2220 PF09983.9 KIK41215.1 - 0.12 11.7 0.0 0.31 10.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) p450 PF00067.22 KIK41216.1 - 3.9e-71 240.2 0.0 4.5e-71 240.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CHAT PF12770.7 KIK41217.1 - 0.058 12.8 0.0 0.058 12.8 0.0 1.1 1 0 0 1 1 1 0 CHAT domain CHAT PF12770.7 KIK41218.1 - 1.7e-27 96.6 1.6 1.8e-27 96.6 1.6 1.0 1 0 0 1 1 1 1 CHAT domain p450 PF00067.22 KIK41219.1 - 3.3e-75 253.6 0.0 3.8e-75 253.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Guanylate_kin PF00625.21 KIK41222.1 - 1e-60 204.5 0.0 1.2e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase MMR_HSR1 PF01926.23 KIK41222.1 - 4e-05 23.7 0.0 8.8e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK41222.1 - 0.00019 21.4 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KIK41222.1 - 0.00045 20.7 0.1 0.0017 18.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KIK41222.1 - 0.00072 19.7 0.1 0.01 16.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK41222.1 - 0.0017 18.6 0.0 0.0078 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KIK41222.1 - 0.0022 18.4 0.0 0.31 11.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KIK41222.1 - 0.003 17.5 0.2 0.0046 16.9 0.0 1.6 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KIK41222.1 - 0.013 15.9 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 KIK41222.1 - 0.027 15.0 0.2 0.04 14.4 0.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KIK41222.1 - 0.027 15.0 0.1 0.084 13.4 0.1 2.0 1 1 1 2 2 2 0 AAA domain MobB PF03205.14 KIK41222.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.15 KIK41222.1 - 0.14 12.0 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ADK PF00406.22 KIK41222.1 - 0.16 12.1 0.1 11 6.1 0.0 2.4 3 0 0 3 3 3 0 Adenylate kinase Roc PF08477.13 KIK41222.1 - 0.19 12.0 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Pkinase PF00069.25 KIK41223.1 - 1.8e-64 217.7 0.0 2.7e-64 217.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK41223.1 - 4.6e-36 124.4 0.0 9.9e-36 123.3 0.0 1.5 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK41223.1 - 1.6e-07 31.0 0.0 2.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIK41223.1 - 0.00029 19.8 0.1 0.00063 18.6 0.1 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIK41223.1 - 0.00047 19.6 1.6 0.00051 19.4 0.2 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK41223.1 - 0.00088 19.3 0.6 0.0019 18.2 0.6 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK41223.1 - 0.013 14.5 0.1 0.019 13.9 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KIK41223.1 - 0.065 12.8 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Rcd1 PF04078.13 KIK41224.1 - 3.4e-125 416.5 3.9 4.1e-125 416.3 3.9 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like T2SSppdC PF12528.8 KIK41224.1 - 0.0041 17.9 1.6 0.021 15.6 0.9 2.4 3 0 0 3 3 3 1 Type II secretion prepilin peptidase dependent protein C F-box-like PF12937.7 KIK41225.1 - 1.2e-10 41.1 0.2 1.2e-10 41.1 0.2 2.4 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 KIK41225.1 - 0.0005 20.4 0.1 1 9.9 0.0 4.6 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIK41225.1 - 0.075 12.8 0.9 7.3 6.4 0.1 3.7 3 2 0 3 3 3 0 Leucine rich repeat FA_hydroxylase PF04116.13 KIK41226.1 - 1.6e-23 83.5 10.6 1.6e-23 83.5 10.6 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily F-box-like PF12937.7 KIK41229.1 - 3.9e-08 33.1 0.9 3.9e-08 33.1 0.9 2.9 3 0 0 3 3 3 1 F-box-like Mus7 PF09462.10 KIK41231.1 - 1.7e-51 175.8 0.2 2.8e-51 175.1 0.2 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family Lactamase_B_2 PF12706.7 KIK41232.1 - 1.9e-13 50.4 1.1 1.4e-12 47.6 1.1 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 KIK41232.1 - 1.5e-10 40.6 0.0 3.6e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 KIK41232.1 - 0.015 15.3 0.4 0.22 11.5 0.1 2.6 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily MFS_1 PF07690.16 KIK41233.1 - 6.6e-30 104.2 28.5 1.1e-29 103.5 28.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK41233.1 - 9.3e-07 28.1 1.1 9.3e-07 28.1 1.1 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter zf-ZPR1 PF03367.13 KIK41235.1 - 1.7e-110 366.0 0.4 8.3e-55 185.0 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 KIK41235.1 - 0.007 16.4 1.2 4.2 7.4 0.1 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KIK41235.1 - 0.012 15.6 4.6 0.29 11.2 0.1 2.9 2 1 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KIK41235.1 - 0.056 13.4 0.9 3.9 7.5 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbons SAM_decarbox PF01536.16 KIK41235.1 - 0.14 11.1 0.0 0.56 9.2 0.0 1.9 2 0 0 2 2 2 0 Adenosylmethionine decarboxylase C1_1 PF00130.22 KIK41235.1 - 0.2 11.6 2.4 3.5 7.6 0.1 2.6 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.14 KIK41235.1 - 0.69 9.9 0.0 0.69 9.9 0.0 3.0 4 0 0 4 4 4 0 Adenylate kinase, active site lid zinc_ribbon_2 PF13240.6 KIK41235.1 - 6.4 6.6 11.5 14 5.6 0.0 3.8 4 0 0 4 4 4 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 KIK41235.1 - 6.6 6.7 6.5 19 5.3 0.2 3.2 2 1 1 3 3 3 0 Putative transposase DNA-binding domain Ribosomal_L28e PF01778.17 KIK41236.1 - 2.3e-39 134.7 1.3 2.3e-39 134.7 1.3 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 KIK41236.1 - 4.7e-28 97.7 12.6 1.2e-27 96.5 12.6 1.7 1 0 0 1 1 1 1 Mak16 protein C-terminal region BUD22 PF09073.10 KIK41236.1 - 1.5e-05 24.5 11.1 2.1e-05 24.1 11.1 1.1 1 0 0 1 1 1 1 BUD22 Exonuc_VII_L PF02601.15 KIK41236.1 - 0.42 10.1 4.3 0.67 9.5 4.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pkinase PF00069.25 KIK41238.1 - 7.3e-10 38.6 0.0 8.5e-10 38.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK41238.1 - 0.0038 16.5 0.0 0.0045 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Phage_Coat_Gp8 PF05371.12 KIK41239.1 - 0.18 11.6 0.1 0.26 11.1 0.1 1.2 1 0 0 1 1 1 0 Phage major coat protein, Gp8 Nrap_D5 PF17406.2 KIK41240.1 - 0.00096 19.0 0.1 4.3 7.1 0.0 3.1 3 0 0 3 3 3 3 Nrap protein PAP/OAS1-like domain 5 TPR_14 PF13428.6 KIK41244.1 - 3.5e-22 77.2 28.7 0.0024 18.5 0.1 12.5 4 2 10 14 14 13 8 Tetratricopeptide repeat HAT PF02184.16 KIK41244.1 - 5.8e-22 77.3 55.3 1.7e-08 34.2 2.4 12.7 12 2 0 12 12 12 5 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 KIK41244.1 - 3.1e-17 62.8 0.3 0.0048 17.4 0.1 6.8 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIK41244.1 - 3.3e-14 51.8 2.2 0.21 11.8 0.0 8.5 10 0 0 10 10 8 3 Tetratricopeptide repeat Suf PF05843.14 KIK41244.1 - 7.8e-14 52.3 14.0 3e-05 24.1 0.3 6.2 3 3 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_16 PF13432.6 KIK41244.1 - 1.3e-09 38.5 15.3 0.19 12.4 0.1 7.6 5 3 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIK41244.1 - 4.7e-09 36.0 0.4 0.00014 22.0 0.3 5.7 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK41244.1 - 6.8e-07 29.0 1.7 38 4.8 0.0 7.3 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK41244.1 - 1.2e-06 28.0 0.6 12 5.9 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_15 PF13429.6 KIK41244.1 - 5.2e-06 25.9 23.7 0.15 11.3 0.0 4.6 2 1 1 4 4 4 3 Tetratricopeptide repeat SNAP PF14938.6 KIK41244.1 - 7.2e-06 25.6 3.5 0.0013 18.2 0.7 3.5 3 0 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KIK41244.1 - 1.7e-05 25.0 10.3 0.068 13.5 0.1 5.9 6 2 0 6 6 5 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KIK41244.1 - 6.5e-05 22.9 20.5 1.1 9.3 0.7 7.1 3 2 4 7 7 7 2 Mad3/BUB1 homology region 1 TPR_9 PF13371.6 KIK41244.1 - 0.0002 21.4 5.4 0.84 9.8 0.1 5.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIK41244.1 - 0.00031 21.2 12.3 13 6.7 0.0 8.2 9 1 0 9 9 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK41244.1 - 0.00048 19.8 0.1 4 7.2 0.0 4.5 4 0 0 4 4 4 1 TPR repeat TPR_7 PF13176.6 KIK41244.1 - 0.0021 17.9 7.4 10 6.4 0.0 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIK41244.1 - 0.022 14.9 3.4 41 4.3 0.1 5.0 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat c-SKI_SMAD_bind PF08782.10 KIK41244.1 - 0.12 12.6 4.5 1.6 9.0 0.4 3.9 4 0 0 4 4 3 0 c-SKI Smad4 binding domain TPR_3 PF07720.12 KIK41244.1 - 0.2 11.7 1.2 24 5.0 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 KIK41244.1 - 0.65 10.1 16.6 0.51 10.4 0.4 5.8 4 3 2 6 6 6 0 U3 small nucleolar RNA-associated protein 6 Wzy_C_2 PF11846.8 KIK41244.1 - 1.3 8.9 5.5 7.4 6.4 0.1 3.4 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal DUF3836 PF12930.7 KIK41244.1 - 4.8 7.0 9.9 1.8 8.3 1.4 2.9 3 0 0 3 3 2 0 Family of unknown function (DUF3836) YlbD_coat PF14071.6 KIK41244.1 - 6 7.1 13.8 64 3.8 6.7 4.3 3 1 0 3 3 2 0 Putative coat protein C2 PF00168.30 KIK41245.1 - 0.0046 17.2 0.0 0.0097 16.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain WD40 PF00400.32 KIK41248.1 - 2.8e-42 141.9 11.0 1.2e-08 35.5 0.8 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41248.1 - 7.5e-22 77.5 1.3 9.1e-05 22.7 0.0 6.2 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK41248.1 - 3.5e-11 42.6 0.0 0.074 12.0 0.0 4.7 3 1 2 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK41248.1 - 4.9e-08 32.1 5.8 0.069 11.8 0.0 5.4 1 1 5 6 6 6 4 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK41248.1 - 0.00069 19.0 0.0 1.4 8.2 0.0 3.2 2 1 1 3 3 3 2 WD40-like domain Nbas_N PF15492.6 KIK41248.1 - 0.0009 18.6 0.7 0.26 10.6 0.0 3.7 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KIK41248.1 - 0.0044 16.9 0.0 23 5.1 0.0 4.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK41248.1 - 0.058 11.7 0.0 1.4 7.1 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_2 PF13360.6 KIK41248.1 - 0.063 12.9 1.8 0.38 10.3 1.7 2.1 1 1 0 1 1 1 0 PQQ-like domain Nucleoporin_N PF08801.11 KIK41248.1 - 0.089 11.5 0.2 20 3.8 0.0 3.6 2 2 1 3 3 3 0 Nup133 N terminal like PALB2_WD40 PF16756.5 KIK41248.1 - 0.1 11.5 3.3 1.4 7.7 0.0 2.9 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Pkinase PF00069.25 KIK41249.1 - 7e-10 38.7 0.0 1.8e-07 30.8 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK41249.1 - 0.00015 21.1 0.0 0.001 18.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase DUF2959 PF11172.8 KIK41251.1 - 0.014 15.6 0.1 0.021 15.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) Pkinase PF00069.25 KIK41252.1 - 9.5e-10 38.3 0.0 8.4e-06 25.3 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK41252.1 - 0.00095 18.5 0.1 0.039 13.2 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KIK41254.1 - 1.2e-09 38.0 0.0 2.3e-06 27.2 0.0 2.5 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK41254.1 - 0.032 13.5 0.0 0.26 10.5 0.0 2.4 1 1 0 2 2 2 0 Protein tyrosine kinase Nucleoporin_FG2 PF15967.5 KIK41255.1 - 0.0094 14.5 3.3 0.011 14.3 3.3 1.1 1 0 0 1 1 1 1 Nucleoporin FG repeated region Pico_P1A PF02226.16 KIK41255.1 - 0.084 12.9 0.1 0.084 12.9 0.1 2.6 2 1 1 3 3 3 0 Picornavirus coat protein (VP4) Pkinase PF00069.25 KIK41256.1 - 1.5e-14 54.0 1.2 0.00072 19.0 0.1 4.5 2 2 1 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 KIK41256.1 - 8.4e-06 25.3 1.0 0.056 12.7 0.0 4.0 3 1 0 4 4 4 2 Protein tyrosine kinase APH PF01636.23 KIK41256.1 - 0.013 15.5 0.1 0.23 11.4 0.1 2.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KIK41256.1 - 1.6 8.0 5.0 0.49 9.7 0.4 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mito_carr PF00153.27 KIK41257.1 - 7.7e-61 202.0 6.8 1.4e-20 73.0 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C2H2 PF00096.26 KIK41258.1 - 6.8e-09 35.7 12.0 0.018 15.5 0.1 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK41258.1 - 0.00011 22.4 5.9 0.0053 17.1 0.5 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK41258.1 - 0.00014 22.4 10.6 0.33 11.9 1.1 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger Spt46 PF17734.1 KIK41258.1 - 0.045 13.6 0.8 0.15 11.8 0.8 1.9 1 0 0 1 1 1 0 Spermatogenesis-associated protein 46 zf-C2H2_8 PF15909.5 KIK41258.1 - 0.39 11.0 3.4 1.9 8.8 3.5 2.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon C1_4 PF07975.12 KIK41258.1 - 2.7 8.3 4.3 8.3 6.7 4.2 1.8 1 1 1 2 2 2 0 TFIIH C1-like domain Metal_resist PF13801.6 KIK41259.1 - 0.016 15.4 0.3 0.017 15.3 0.3 1.1 1 0 0 1 1 1 0 Heavy-metal resistance NUDIX PF00293.28 KIK41261.1 - 1.2e-17 64.2 0.0 1.9e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KIK41261.1 - 8e-13 48.9 0.1 1.9e-12 47.8 0.1 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KIK41261.1 - 0.004 16.8 0.4 0.0077 15.9 0.4 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 KIK41261.1 - 0.042 13.6 0.4 0.088 12.6 0.4 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Nudix_N_2 PF14803.6 KIK41261.1 - 0.07 13.1 0.8 0.19 11.7 0.1 1.9 2 0 0 2 2 2 0 Nudix N-terminal Glyco_hydro_18 PF00704.28 KIK41262.1 - 1.5e-56 192.4 2.5 1.8e-56 192.2 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GHL10 PF02638.15 KIK41262.1 - 0.074 12.1 0.0 0.17 10.9 0.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase-like 10 Glyco_hydro_114 PF03537.13 KIK41262.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.5 2 0 0 2 2 2 0 Glycoside-hydrolase family GH114 CoA_binding_2 PF13380.6 KIK41263.1 - 3.5e-26 92.0 0.0 3.8e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain PALP PF00291.25 KIK41265.1 - 1.2e-60 205.4 0.0 6e-58 196.6 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NAD_binding_7 PF13241.6 KIK41265.1 - 0.14 12.6 0.2 0.29 11.6 0.2 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding SWIRM PF04433.17 KIK41266.1 - 1.9e-10 41.0 0.0 3.9e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 KIK41266.1 - 1.5e-09 37.9 0.0 3.2e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK41266.1 - 0.00018 21.7 0.0 0.00041 20.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain 2-oxoacid_dh PF00198.23 KIK41275.1 - 7.4e-49 166.3 0.0 3.1e-48 164.2 0.0 1.9 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KIK41275.1 - 1.3e-19 69.8 0.9 2.3e-19 69.0 0.9 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KIK41275.1 - 4.4e-11 42.9 0.2 8e-11 42.1 0.2 1.5 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KIK41275.1 - 9.7e-06 25.3 0.4 2.5e-05 24.0 0.4 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD_3 PF13437.6 KIK41275.1 - 0.0028 18.3 0.1 0.014 16.1 0.0 2.2 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 KIK41275.1 - 0.033 13.4 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion F-box-like PF12937.7 KIK41276.1 - 1.1e-07 31.6 2.4 2.4e-07 30.5 1.0 2.3 2 0 0 2 2 2 1 F-box-like Peptidase_C14 PF00656.22 KIK41280.1 - 6.8e-35 121.2 0.0 4.2e-22 79.3 0.0 2.0 2 0 0 2 2 2 2 Caspase domain Peptidase_C14 PF00656.22 KIK41281.1 - 3.6e-31 109.0 0.0 5e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain CAP59_mtransfer PF11735.8 KIK41283.1 - 1.3e-66 224.8 0.0 1.9e-66 224.2 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Peptidase_C14 PF00656.22 KIK41284.1 - 4.1e-61 207.1 0.0 5.4e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain zf-C2H2 PF00096.26 KIK41285.1 - 1.2e-05 25.5 8.1 0.002 18.5 0.5 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK41285.1 - 0.00022 21.8 10.6 0.0094 16.7 0.3 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KIK41285.1 - 0.0015 18.5 3.0 0.012 15.5 0.2 2.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK41285.1 - 0.05 13.9 2.0 1.1 9.6 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KIK41285.1 - 0.084 13.3 4.3 0.093 13.2 0.1 2.7 2 1 0 2 2 2 0 Zinc-finger double domain zf-met PF12874.7 KIK41285.1 - 0.16 12.4 2.6 0.6 10.6 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KIK41285.1 - 0.74 9.6 4.6 1.7 8.5 0.8 3.0 2 1 1 3 3 3 0 zinc-finger C2H2-type zf-Di19 PF05605.12 KIK41285.1 - 0.79 10.1 6.7 0.18 12.1 0.9 2.4 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF35_N PF12172.8 KIK41286.1 - 0.041 13.8 0.1 0.088 12.7 0.1 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DHHA2 PF02833.14 KIK41289.1 - 4.7e-23 82.0 0.1 9.7e-23 80.9 0.1 1.5 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 KIK41289.1 - 0.00061 20.0 0.0 0.069 13.4 0.0 3.0 2 1 0 2 2 2 1 DHH family GMC_oxred_N PF00732.19 KIK41291.1 - 2.6e-52 178.1 0.0 3.8e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK41291.1 - 1e-27 97.4 0.0 2.1e-27 96.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KIK41291.1 - 0.023 13.8 1.6 0.16 11.0 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 KIK41291.1 - 0.056 12.5 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 KIK41291.1 - 0.083 13.1 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Methyltransf_16 PF10294.9 KIK41292.1 - 3.4e-14 52.9 0.0 5.6e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KIK41292.1 - 0.0007 20.2 0.0 0.0039 17.9 0.0 2.3 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK41292.1 - 0.0013 19.5 0.1 0.0044 17.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DUF3918 PF13056.6 KIK41292.1 - 0.009 15.6 0.2 0.021 14.4 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3918) DUF3752 PF12572.8 KIK41293.1 - 4.3e-42 144.2 12.1 4.3e-42 144.2 12.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) DSPc PF00782.20 KIK41296.1 - 6.6e-06 26.0 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KIK41296.1 - 8.1e-05 22.7 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KIK41296.1 - 0.00014 21.5 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KIK41296.1 - 0.00085 19.5 0.0 0.0041 17.3 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate CDKN3 PF05706.12 KIK41296.1 - 0.0044 16.7 0.0 0.0058 16.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DLP_helical PF18709.1 KIK41298.1 - 0.037 13.2 0.0 0.062 12.5 0.0 1.3 1 1 0 1 1 1 0 Dynamin-like helical domain DUF805 PF05656.14 KIK41298.1 - 0.092 13.2 5.2 0.22 12.0 5.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF805) p450 PF00067.22 KIK41299.1 - 2.2e-68 231.1 0.0 2.8e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LysM PF01476.20 KIK41301.1 - 1.9e-07 31.0 0.0 1.2e-05 25.2 0.0 2.1 2 0 0 2 2 2 2 LysM domain NODP PF07684.12 KIK41301.1 - 0.002 18.2 0.1 0.0034 17.5 0.1 1.4 1 0 0 1 1 1 1 NOTCH protein GXGXG PF01493.19 KIK41301.1 - 0.073 12.7 0.0 0.085 12.4 0.0 1.1 1 0 0 1 1 1 0 GXGXG motif p450 PF00067.22 KIK41303.1 - 2.9e-10 39.5 0.0 3.5e-10 39.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 KIK41304.1 - 1e-37 127.4 12.1 3.9e-07 30.7 0.4 8.1 7 1 1 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41304.1 - 3.9e-13 49.5 0.3 0.0065 16.7 0.1 5.4 1 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK41304.1 - 3.4e-06 27.1 0.0 0.12 12.3 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A TPR_2 PF07719.17 KIK41304.1 - 0.0027 17.7 0.4 58 4.2 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK41304.1 - 0.0039 17.9 1.0 1.1 10.3 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat IKI3 PF04762.12 KIK41304.1 - 0.011 13.8 0.0 0.069 11.1 0.0 2.2 2 0 0 2 2 2 0 IKI3 family Ge1_WD40 PF16529.5 KIK41304.1 - 0.027 13.4 0.4 2.9 6.7 0.3 3.1 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein GPI-anchored PF10342.9 KIK41308.1 - 6.7e-06 26.8 0.0 8.6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Plant_zn_clust PF10533.9 KIK41310.1 - 0.35 10.9 3.3 0.25 11.4 1.5 1.6 2 0 0 2 2 2 0 Plant zinc cluster domain Urm1 PF09138.11 KIK41311.1 - 3.1e-30 104.4 0.0 2e-29 101.8 0.0 1.8 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KIK41311.1 - 0.0034 18.0 0.0 0.0047 17.5 0.0 1.3 1 0 0 1 1 1 1 ThiS family GTP1_OBG PF01018.22 KIK41312.1 - 1.1e-39 135.6 2.0 2.8e-28 98.5 0.5 2.4 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 KIK41312.1 - 5e-19 68.5 0.0 1e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KIK41312.1 - 6.6e-05 22.4 0.4 0.16 11.4 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family cobW PF02492.19 KIK41312.1 - 7.1e-05 22.5 0.0 0.027 14.0 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 KIK41312.1 - 0.00014 21.5 0.0 0.00032 20.2 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KIK41312.1 - 0.00022 21.3 0.0 0.00044 20.4 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.27 KIK41312.1 - 0.0016 18.0 0.1 0.25 10.9 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KIK41312.1 - 0.0089 16.5 0.0 0.031 14.8 0.0 1.9 2 0 0 2 2 2 1 ABC transporter MeaB PF03308.16 KIK41312.1 - 0.048 12.6 2.1 0.83 8.6 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KIK41312.1 - 0.06 13.9 0.3 0.3 11.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain Gtr1_RagA PF04670.12 KIK41312.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ploopntkinase3 PF18751.1 KIK41312.1 - 0.32 10.9 0.0 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 HLH PF00010.26 KIK41313.1 - 1.2e-11 44.4 0.5 2.4e-11 43.4 0.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Voldacs PF03517.13 KIK41313.1 - 0.017 15.2 0.1 0.043 13.9 0.1 1.6 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling p450 PF00067.22 KIK41315.1 - 3.2e-74 250.3 0.0 3.9e-74 250.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPR_19 PF14559.6 KIK41316.1 - 5.1e-09 36.5 0.5 0.14 12.7 0.0 3.9 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIK41316.1 - 3.9e-07 30.3 0.7 0.047 14.5 0.0 5.2 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK41316.1 - 0.00047 20.1 0.0 0.043 13.9 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIK41316.1 - 0.00071 19.7 1.0 0.63 10.2 0.0 2.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK41316.1 - 0.0018 18.9 1.5 0.46 11.2 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK41316.1 - 0.0049 17.0 0.1 0.13 12.6 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK41316.1 - 0.0094 15.7 0.0 0.54 10.2 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK41316.1 - 0.018 14.7 0.0 0.4 10.4 0.0 2.4 2 0 0 2 2 2 0 TPR repeat TPR_6 PF13174.6 KIK41316.1 - 0.043 14.5 0.1 5.9 7.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.10 KIK41316.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) HET PF06985.11 KIK41317.1 - 1.4e-11 44.9 3.3 4.4e-11 43.3 3.3 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAA_hydrolase PF01557.18 KIK41318.1 - 1.8e-43 148.8 0.0 2.2e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KIK41318.1 - 1.3e-30 105.7 0.0 2.2e-29 101.8 0.0 2.2 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Peptidase_S24 PF00717.23 KIK41319.1 - 5.8e-08 32.6 0.0 8.9e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like DUF4399 PF14347.6 KIK41319.1 - 0.0068 16.8 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4399) NACHT PF05729.12 KIK41321.1 - 1.3e-09 38.1 0.0 2.4e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK41321.1 - 3.3e-09 37.4 0.1 5.9e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK41321.1 - 0.015 15.5 0.1 0.077 13.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 KIK41321.1 - 0.018 15.2 0.0 0.036 14.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KIK41321.1 - 0.021 15.2 0.0 0.037 14.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 KIK41321.1 - 0.041 13.1 0.0 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain APS_kinase PF01583.20 KIK41321.1 - 0.078 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 KIK41321.1 - 0.1 13.2 0.0 0.29 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 KIK41321.1 - 0.11 11.7 0.0 0.85 8.7 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Zn_clus PF00172.18 KIK41323.1 - 4.6e-06 26.7 6.2 5.4e-06 26.4 6.2 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIK41324.1 - 4.7e-08 32.4 0.0 5.6e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KIK41325.1 - 4.6e-15 55.4 56.5 6e-13 48.4 26.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.7 KIK41327.1 - 6.1e-12 46.0 0.0 1.6e-07 31.8 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) NACHT PF05729.12 KIK41327.1 - 3e-10 40.3 0.2 7.8e-10 38.9 0.2 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK41327.1 - 2.3e-05 24.8 0.7 0.0001 22.7 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain Ank PF00023.30 KIK41327.1 - 0.002 18.5 0.6 10 6.8 0.1 4.7 5 0 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.6 KIK41327.1 - 0.0034 17.8 3.2 92 4.1 0.0 6.3 6 1 0 6 6 6 0 Ankyrin repeat Tombus_P19 PF03220.13 KIK41327.1 - 0.0062 16.3 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Tombusvirus P19 core protein Helo_like_N PF17111.5 KIK41327.1 - 0.0071 15.7 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 KIK41327.1 - 0.0078 16.5 0.1 0.031 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KIK41327.1 - 0.01 15.9 0.0 5.1 7.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 KIK41327.1 - 0.039 14.4 0.2 3.6 8.0 0.2 3.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ank_4 PF13637.6 KIK41327.1 - 0.093 13.3 0.3 15 6.3 0.0 3.6 2 1 1 3 3 3 0 Ankyrin repeats (many copies) RNA_helicase PF00910.22 KIK41327.1 - 0.12 12.7 0.0 1 9.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 KIK41327.1 - 2.9 7.0 4.8 0.72 9.0 0.1 2.4 2 1 1 3 3 3 0 NB-ARC domain STAG PF08514.11 KIK41328.1 - 5.4e-34 116.5 0.1 1.9e-33 114.8 0.1 2.0 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.6 KIK41328.1 - 5.7e-05 23.4 0.2 0.00055 20.3 0.0 2.9 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.22 KIK41328.1 - 0.00062 19.8 5.0 7.3 7.1 0.0 6.2 7 1 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 KIK41328.1 - 0.48 11.0 2.2 2.2 8.9 0.5 3.3 2 0 0 2 2 2 0 HEAT-like repeat Ribosomal_S30 PF04758.14 KIK41330.1 - 6.4e-28 96.7 7.3 6.9e-28 96.6 7.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Bap31_Bap29_C PF18035.1 KIK41332.1 - 0.0064 16.5 1.5 0.024 14.6 0.7 2.1 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4201 PF13870.6 KIK41332.1 - 0.14 11.9 6.6 0.081 12.7 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) SPACA9 PF15120.6 KIK41332.1 - 0.17 11.6 0.7 0.38 10.5 0.7 1.6 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 GAS PF13851.6 KIK41332.1 - 0.24 10.8 9.0 0.061 12.7 3.7 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding GARP PF16731.5 KIK41332.1 - 0.41 10.3 7.5 1.2 8.8 7.5 1.8 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma Cep57_CLD_2 PF14197.6 KIK41332.1 - 0.74 9.9 5.0 1.4 9.1 2.5 2.7 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Jnk-SapK_ap_N PF09744.9 KIK41332.1 - 1.4 9.1 8.5 1.3 9.2 2.8 2.6 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 SlyX PF04102.12 KIK41332.1 - 4.5 8.0 6.2 9.1 7.0 0.3 3.3 1 1 1 2 2 2 0 SlyX TMF_TATA_bd PF12325.8 KIK41332.1 - 4.9 7.4 11.0 6 7.1 4.8 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding PEP-utilisers_N PF05524.13 KIK41332.1 - 6.6 6.9 9.4 6 7.1 6.3 2.4 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal WD40 PF00400.32 KIK41336.1 - 3.4e-12 46.7 1.2 7.7e-10 39.2 0.0 2.0 2 0 0 2 2 2 2 WD domain, G-beta repeat Ret2_MD PF18528.1 KIK41336.1 - 0.2 12.1 0.0 0.21 12.0 0.0 1.1 1 0 0 1 1 1 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Kelch_1 PF01344.25 KIK41339.1 - 0.077 12.6 0.3 0.2 11.3 0.1 1.9 2 0 0 2 2 2 0 Kelch motif Gln-synt_C PF00120.24 KIK41340.1 - 2.5e-80 270.1 0.0 9.5e-80 268.2 0.0 1.7 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF5436 PF17504.2 KIK41341.1 - 0.23 11.8 2.1 0.26 11.6 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5436) Wzz PF02706.15 KIK41341.1 - 0.35 11.2 1.8 3.1 8.2 0.0 2.7 2 0 0 2 2 2 0 Chain length determinant protein WD40 PF00400.32 KIK41345.1 - 8.8e-39 130.8 23.8 2.3e-06 28.2 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41345.1 - 5.1e-13 49.1 11.2 0.013 15.8 0.2 6.2 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK41345.1 - 3.5e-06 26.2 1.7 0.33 9.9 0.0 4.5 1 1 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 KIK41345.1 - 5.5e-05 23.5 5.7 0.61 10.7 0.0 4.3 3 1 1 4 4 4 2 PQQ-like domain Nup160 PF11715.8 KIK41345.1 - 0.00024 19.9 12.0 0.041 12.5 2.2 4.2 2 2 0 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KIK41345.1 - 0.016 13.7 0.1 0.1 11.1 0.0 2.2 2 1 0 2 2 2 0 Cytochrome D1 heme domain Nbas_N PF15492.6 KIK41345.1 - 0.021 14.1 0.5 1 8.6 0.1 3.3 2 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK41345.1 - 0.12 11.7 0.0 23 4.2 0.0 2.8 2 2 1 3 3 3 0 WD40-like domain DUF4662 PF15578.6 KIK41346.1 - 0.054 13.3 0.0 0.057 13.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) DUF5042 PF16445.5 KIK41347.1 - 0.12 10.8 0.0 0.13 10.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5042) SLATT_fungal PF18142.1 KIK41348.1 - 7.7e-05 22.7 0.4 9.4e-05 22.4 0.4 1.1 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain SLATT_fungal PF18142.1 KIK41349.1 - 5.1e-18 65.2 0.0 5.6e-18 65.1 0.0 1.0 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Glycos_transf_3 PF00591.21 KIK41351.1 - 1e-75 254.6 0.0 1.3e-75 254.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KIK41351.1 - 1.2e-08 34.7 0.5 4.3e-08 32.9 0.1 2.2 3 0 0 3 3 3 1 Glycosyl transferase family, helical bundle domain WI12 PF07107.11 KIK41351.1 - 0.045 13.9 0.1 0.11 12.6 0.0 1.6 2 0 0 2 2 2 0 Wound-induced protein WI12 H_PPase PF03030.16 KIK41351.1 - 0.65 8.6 4.4 7.4 5.1 1.2 2.1 2 0 0 2 2 2 0 Inorganic H+ pyrophosphatase MFS_1 PF07690.16 KIK41352.1 - 6.6e-23 81.2 43.4 3e-21 75.7 35.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3382 PF11862.8 KIK41352.1 - 0.06 13.6 0.1 0.06 13.6 0.1 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF3382) MFS_1 PF07690.16 KIK41353.1 - 1.1e-20 74.0 39.4 1.1e-20 74.0 39.4 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KIK41354.1 - 5.6e-26 91.3 40.4 7.6e-24 84.3 32.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIK41354.1 - 0.02 14.2 28.4 0.2 10.9 28.7 2.0 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB TetR_C_16 PF17920.1 KIK41354.1 - 2.1 8.6 9.2 4.5 7.5 0.7 3.3 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Acetyltransf_10 PF13673.7 KIK41355.1 - 3.9e-09 36.5 0.0 5.6e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK41355.1 - 1.5e-07 31.7 0.0 2.1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK41355.1 - 0.0008 19.8 0.0 0.0013 19.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain BRK PF07533.16 KIK41356.1 - 0.15 11.8 0.2 10 5.9 0.0 2.3 2 0 0 2 2 2 0 BRK domain UQ_con PF00179.26 KIK41357.1 - 3.7e-40 136.8 0.0 4.7e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 KIK41357.1 - 3e-21 75.0 0.5 5.7e-21 74.1 0.5 1.5 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain UBA_6 PF18039.1 KIK41357.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain Prok-E2_B PF14461.6 KIK41357.1 - 0.053 13.2 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Coprogen_oxidas PF01218.18 KIK41358.1 - 1.7e-128 427.5 0.0 1.9e-128 427.3 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase CsbD PF05532.12 KIK41359.1 - 7.6e-14 51.4 12.6 1.6e-09 37.5 1.6 2.1 1 1 1 2 2 2 2 CsbD-like HSP9_HSP12 PF04119.12 KIK41359.1 - 0.056 13.8 0.3 0.16 12.4 0.2 1.9 1 1 0 1 1 1 0 Heat shock protein 9/12 CODH_A_N PF18537.1 KIK41359.1 - 0.094 12.7 0.1 2.6 8.1 0.0 2.1 1 1 1 2 2 2 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain Clat_adaptor_s PF01217.20 KIK41360.1 - 9e-57 191.0 3.1 9.9e-57 190.9 3.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PCAF_N PF06466.11 KIK41360.1 - 0.0042 16.7 0.1 0.005 16.4 0.1 1.1 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain ArfGap PF01412.18 KIK41361.1 - 1.6e-33 115.2 1.7 1.8e-33 115.1 0.3 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Casc1_N PF15927.5 KIK41361.1 - 4.2 7.0 10.6 9.1 5.9 10.6 1.5 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Skp1_POZ PF03931.15 KIK41362.1 - 9.4e-20 70.6 0.2 1.4e-19 70.0 0.2 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 KIK41362.1 - 5.9e-10 39.1 0.0 1.1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain BTB PF00651.31 KIK41362.1 - 0.027 14.7 0.0 0.23 11.7 0.0 2.0 1 1 0 1 1 1 0 BTB/POZ domain TrbE PF11100.8 KIK41362.1 - 0.16 12.2 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Conjugal transfer protein TrbE DUF2554 PF10829.8 KIK41364.1 - 0.014 15.7 0.1 0.018 15.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2554) Nif11 PF07862.11 KIK41364.1 - 0.025 14.9 0.1 0.04 14.2 0.1 1.3 1 0 0 1 1 1 0 Nif11 domain WD40 PF00400.32 KIK41365.1 - 4.6e-14 52.6 5.0 5.9e-05 23.8 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Glyoxal_oxid_N PF07250.11 KIK41365.1 - 0.039 13.1 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus Nup160 PF11715.8 KIK41365.1 - 0.04 12.6 0.2 0.057 12.0 0.2 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Kelch_6 PF13964.6 KIK41365.1 - 0.04 14.2 0.4 0.39 11.1 0.0 2.4 2 1 0 2 2 2 0 Kelch motif PQQ_3 PF13570.6 KIK41365.1 - 0.057 13.9 0.1 0.15 12.6 0.1 1.7 1 0 0 1 1 1 0 PQQ-like domain HisG PF01634.18 KIK41369.1 - 1e-50 171.9 0.0 1.3e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KIK41369.1 - 2.1e-28 98.2 0.1 6.3e-28 96.7 0.1 1.8 2 0 0 2 2 2 1 HisG, C-terminal domain NMT1 PF09084.11 KIK41369.1 - 0.00028 20.9 0.1 0.00049 20.1 0.1 1.4 1 0 0 1 1 1 1 NMT1/THI5 like GvpO PF05800.11 KIK41369.1 - 0.17 11.9 0.1 4.2 7.4 0.1 2.4 2 1 0 2 2 2 0 Gas vesicle synthesis protein GvpO Proteasome PF00227.26 KIK41370.1 - 2.4e-32 112.0 0.0 2.9e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Rot1 PF10681.9 KIK41371.1 - 8.9e-59 198.5 2.0 1.1e-58 198.3 2.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal DUF5640 PF18692.1 KIK41371.1 - 0.23 11.5 1.6 2.2 8.4 0.1 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5640) Pkinase PF00069.25 KIK41372.1 - 1.8e-36 125.9 0.0 3e-24 85.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK41372.1 - 5e-23 81.7 0.0 1.8e-18 66.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK41372.1 - 0.0092 15.0 0.1 0.015 14.2 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KIK41372.1 - 0.015 14.1 0.1 0.026 13.3 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KIK41372.1 - 0.24 10.7 0.0 16 4.7 0.0 2.2 2 0 0 2 2 2 0 Kinase-like SWI-SNF_Ssr4 PF08549.10 KIK41373.1 - 2.8e-25 89.1 4.7 1.6e-18 66.7 0.3 2.2 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1750) CG-1 PF03859.16 KIK41373.1 - 0.012 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 CG-1 domain NT5C PF06941.12 KIK41373.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) DUF1192 PF06698.11 KIK41373.1 - 0.17 12.0 2.0 0.47 10.6 2.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) MFS_1 PF07690.16 KIK41376.1 - 1.4e-17 63.7 14.9 1.5e-17 63.6 14.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK41376.1 - 0.0069 15.3 4.9 0.01 14.7 4.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 KIK41376.1 - 0.099 10.9 1.1 0.1 10.8 1.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CPP1-like PF11833.8 KIK41376.1 - 2.8 7.6 6.5 0.16 11.6 1.4 1.5 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like MFS_1 PF07690.16 KIK41377.1 - 0.0018 17.2 6.9 0.0018 17.2 6.9 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1118 PF06549.12 KIK41377.1 - 1.1 9.5 4.6 1.2 9.5 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1118) MFS_1 PF07690.16 KIK41378.1 - 8.7e-30 103.8 34.2 8.7e-30 103.8 34.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK41378.1 - 0.00085 18.3 11.1 0.00085 18.3 11.1 2.1 3 0 0 3 3 3 1 Sugar (and other) transporter C2 PF00168.30 KIK41379.1 - 9e-09 35.6 0.1 1.6e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 C2 domain Phage_int_SAM_1 PF02899.17 KIK41381.1 - 0.14 12.5 0.6 0.37 11.1 0.2 2.0 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain LapA_dom PF06305.11 KIK41381.1 - 0.74 9.7 0.0 0.74 9.7 0.0 2.3 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain BAG PF02179.16 KIK41384.1 - 0.00029 21.2 0.0 0.00073 19.9 0.0 1.6 1 0 0 1 1 1 1 BAG domain NUDE_C PF04880.13 KIK41386.1 - 0.23 11.9 2.5 0.23 11.9 2.5 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region FAD_binding_7 PF03441.14 KIK41389.1 - 0.18 11.3 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase MFS_1 PF07690.16 KIK41394.1 - 5.5e-47 160.4 39.4 3.5e-45 154.4 41.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK41394.1 - 1.3e-08 33.8 7.5 1.7e-08 33.4 7.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIK41394.1 - 4.4e-08 32.4 29.4 6.5e-08 31.9 13.4 3.8 3 1 0 3 3 3 2 Sugar (and other) transporter DUF3392 PF11872.8 KIK41394.1 - 0.5 10.7 4.0 5.5 7.3 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3392) Fe-S_biosyn PF01521.20 KIK41395.1 - 1.4e-12 47.8 0.0 1.8e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Curto_V3 PF07436.11 KIK41396.1 - 0.14 12.6 0.1 0.17 12.3 0.1 1.2 1 1 0 1 1 1 0 Curtovirus V3 protein BRF1 PF07741.13 KIK41398.1 - 8 6.9 9.4 19 5.7 9.4 1.7 1 1 0 1 1 1 0 Brf1-like TBP-binding domain Shugoshin_C PF07557.11 KIK41400.1 - 5.6e-10 38.8 4.2 5.6e-10 38.8 4.2 3.0 3 0 0 3 3 3 1 Shugoshin C terminus Shugoshin_N PF07558.11 KIK41400.1 - 7e-07 29.0 2.1 7e-07 29.0 2.1 2.1 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region CENP-H PF05837.12 KIK41400.1 - 0.13 12.7 0.3 0.13 12.7 0.3 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) YabA PF06156.13 KIK41400.1 - 3.1 8.5 4.7 1.1 9.9 1.8 1.7 2 0 0 2 2 2 0 Initiation control protein YabA Cyclase PF04199.13 KIK41401.1 - 4.8e-14 52.7 0.0 6.4e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Pkinase PF00069.25 KIK41402.1 - 1.9e-51 174.9 0.0 3.3e-51 174.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK41402.1 - 8.3e-26 90.8 0.2 2.3e-25 89.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK41402.1 - 0.0017 17.2 1.0 0.0017 17.2 1.0 2.1 2 1 0 2 2 2 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 KIK41402.1 - 0.013 14.5 0.1 0.02 13.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Myb_DNA-bind_2 PF08914.11 KIK41403.1 - 5.1e-07 29.8 4.5 4.2e-06 26.8 4.5 2.3 1 1 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.10 KIK41403.1 - 0.014 16.0 6.1 0.55 10.8 6.1 2.2 1 1 0 1 1 1 0 Rap1, DNA-binding BRCT_2 PF16589.5 KIK41404.1 - 1.4e-05 25.4 0.0 2.4e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Arb1 PF09692.10 KIK41406.1 - 9.5e-09 34.9 0.2 4.3e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Ser_hydrolase PF06821.13 KIK41407.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Pkinase_Tyr PF07714.17 KIK41408.1 - 5.6e-27 94.6 0.0 6.1e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK41408.1 - 1.1e-24 87.2 0.0 1.2e-24 87.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK41408.1 - 0.0012 18.2 0.0 0.0017 17.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK41408.1 - 0.0066 15.3 0.0 0.0073 15.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK41408.1 - 0.0081 16.1 0.1 0.0099 15.8 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK41408.1 - 0.0087 15.7 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KIK41408.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.25 KIK41411.1 - 1e-38 133.2 0.0 1.3e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK41411.1 - 6.1e-20 71.6 0.0 1.1e-19 70.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK41411.1 - 1.2e-05 24.3 0.0 2.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIK41411.1 - 2e-05 24.1 0.0 3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK41411.1 - 0.00083 19.3 0.0 0.0027 17.6 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK41411.1 - 0.034 13.1 0.1 0.064 12.2 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 KIK41411.1 - 0.058 12.7 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.11 KIK41411.1 - 0.16 10.9 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ABC_tran PF00005.27 KIK41413.1 - 1.1e-25 90.7 0.1 2.4e-25 89.7 0.1 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIK41413.1 - 6.8e-08 32.7 0.1 0.0001 22.2 0.2 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIK41413.1 - 2.2e-06 27.3 0.5 0.056 12.9 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KIK41413.1 - 0.0001 22.2 0.6 0.00039 20.3 0.3 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KIK41413.1 - 0.00012 22.6 0.4 0.00025 21.6 0.5 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIK41413.1 - 0.00024 20.9 0.0 0.0053 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIK41413.1 - 0.0012 18.6 0.1 0.0025 17.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KIK41413.1 - 0.0014 19.1 0.0 0.0034 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIK41413.1 - 0.0082 16.1 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KIK41413.1 - 0.0089 16.3 0.0 0.089 13.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 KIK41413.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 KIK41413.1 - 0.013 15.8 0.1 0.5 10.7 0.1 2.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KIK41413.1 - 0.018 14.4 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 KIK41413.1 - 0.031 14.5 0.1 0.078 13.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_27 PF13514.6 KIK41413.1 - 0.052 13.1 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KIK41413.1 - 0.069 12.3 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_14 PF13173.6 KIK41413.1 - 0.1 12.6 0.0 0.35 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KIK41413.1 - 0.11 11.9 0.1 0.27 10.5 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.6 KIK41413.1 - 0.14 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KIK41413.1 - 0.17 11.4 0.0 0.73 9.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KIK41413.1 - 0.17 12.4 0.1 0.6 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KIK41413.1 - 0.24 11.0 0.3 0.72 9.4 0.3 1.8 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Coa1 PF08695.10 KIK41414.1 - 7.6e-32 109.5 0.0 9.5e-32 109.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Harakiri PF15196.6 KIK41414.1 - 0.0091 16.4 0.3 0.034 14.6 0.3 1.9 2 0 0 2 2 2 1 Activator of apoptosis harakiri TIM21 PF08294.11 KIK41414.1 - 0.051 13.5 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 TIM21 His_Phos_2 PF00328.22 KIK41415.1 - 1.2e-44 153.2 0.0 1.5e-44 153.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) LSM14 PF12701.7 KIK41416.1 - 1.8e-25 88.8 0.0 3e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KIK41416.1 - 3.7e-09 37.4 3.6 6.6e-09 36.6 3.6 1.3 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.6 KIK41416.1 - 0.00025 21.1 0.0 0.00054 20.0 0.0 1.6 2 0 0 2 2 2 1 Ataxin 2 SM domain DUF3987 PF13148.6 KIK41417.1 - 3.8 6.4 7.9 0.34 9.9 3.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF2058 PF09831.9 KIK41417.1 - 5 7.2 11.1 4.7 7.3 5.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) CMS1 PF14617.6 KIK41417.1 - 9.5 5.5 8.2 16 4.7 2.2 2.1 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Adenylsucc_synt PF00709.21 KIK41418.1 - 1.6e-172 574.2 0.0 1.8e-172 574.0 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase COX16 PF14138.6 KIK41419.1 - 1.6e-29 102.2 0.0 1.9e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 YjcZ_2 PF09680.10 KIK41419.1 - 0.08 12.6 0.3 0.12 12.1 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function FMN_dh PF01070.18 KIK41420.1 - 2e-108 362.5 0.4 2.5e-108 362.2 0.4 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 KIK41420.1 - 2.6e-05 23.6 0.2 0.055 12.8 0.1 2.4 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 KIK41420.1 - 0.00068 18.7 3.9 0.0047 16.0 0.9 2.7 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KIK41420.1 - 0.002 17.6 1.4 0.0036 16.7 1.4 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 KIK41420.1 - 0.0023 17.1 0.1 0.0037 16.5 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_Phos_1 PF00300.22 KIK41422.1 - 1.2e-30 106.7 1.3 1.7e-29 102.9 1.3 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PFU PF09070.11 KIK41423.1 - 1.4e-43 147.7 0.3 3.5e-43 146.5 0.3 1.7 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 KIK41423.1 - 1.2e-41 142.7 0.0 1.7e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 KIK41423.1 - 8.6e-31 105.5 9.5 1.7e-06 28.7 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.6 KIK41423.1 - 2.1e-06 27.7 0.1 0.027 14.5 0.0 3.0 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region HORMA PF02301.18 KIK41425.1 - 9.2e-65 218.2 0.0 1.8e-64 217.2 0.0 1.5 2 0 0 2 2 2 1 HORMA domain PHD PF00628.29 KIK41425.1 - 8.4e-05 22.4 4.7 0.00016 21.5 4.7 1.5 1 0 0 1 1 1 1 PHD-finger MarR PF01047.22 KIK41425.1 - 0.066 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 MarR family Sybindin PF04099.12 KIK41426.1 - 1.1e-40 138.9 0.0 1.3e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KIK41426.1 - 6.5e-08 32.8 0.0 6.7e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Peptidase_M28 PF04389.17 KIK41427.1 - 4.2e-37 127.8 0.0 1.5e-36 126.0 0.0 1.9 2 1 0 2 2 2 1 Peptidase family M28 DUF5344 PF17279.2 KIK41428.1 - 0.0064 17.1 0.2 0.42 11.2 0.0 2.6 1 1 1 2 2 2 1 Family of unknown function (DUF5344) CSS-motif PF12792.7 KIK41428.1 - 0.093 12.2 0.7 0.14 11.6 0.7 1.3 1 0 0 1 1 1 0 CSS motif domain associated with EAL RdRP PF05183.12 KIK41429.1 - 7.9e-171 569.6 0.0 1e-170 569.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase PI3_PI4_kinase PF00454.27 KIK41430.1 - 1.1e-24 87.6 0.5 3.5e-17 63.0 0.5 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KIK41430.1 - 1.5e-19 70.1 0.0 4.6e-19 68.5 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) TetR_C_4 PF08359.11 KIK41430.1 - 0.093 12.9 0.1 0.35 11.0 0.1 2.0 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region Cu-oxidase PF00394.22 KIK41431.1 - 2.6e-42 144.7 0.9 5.2e-40 137.2 0.0 3.2 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK41431.1 - 1.2e-37 128.7 0.1 1.2e-37 128.7 0.1 3.3 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK41431.1 - 5.6e-37 126.4 5.0 2.1e-36 124.5 0.8 2.9 3 1 0 3 3 3 1 Multicopper oxidase WD40 PF00400.32 KIK41433.1 - 2.6e-118 382.5 58.2 1.7e-09 38.2 0.0 15.1 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41433.1 - 6.1e-28 97.0 14.3 0.05 13.9 0.0 12.3 1 1 13 14 14 14 8 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KIK41433.1 - 2.9e-11 42.8 16.6 0.7 8.6 0.0 10.5 1 1 10 11 11 11 4 Nup133 N terminal like WD40_like PF17005.5 KIK41433.1 - 1.3e-10 41.1 0.0 5.4 6.2 0.0 8.6 6 2 3 11 11 11 2 WD40-like domain Ge1_WD40 PF16529.5 KIK41433.1 - 1.6e-10 40.5 2.7 3.6 6.5 0.2 9.3 2 2 5 9 9 9 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK41433.1 - 9.2e-09 34.5 16.2 3.3 6.2 0.0 11.9 9 4 4 14 14 14 1 Nucleoporin Nup120/160 PD40 PF07676.12 KIK41433.1 - 2.1e-08 33.9 11.3 4 7.5 0.0 9.7 11 0 0 11 11 11 1 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK41433.1 - 7.3e-06 24.6 0.0 7.2 4.8 0.0 5.8 3 2 4 7 7 7 1 WD repeat-containing and planar cell polarity effector protein Fritz NACHT PF05729.12 KIK41433.1 - 3.9e-05 23.6 0.0 8.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Peptidase_S9_N PF02897.15 KIK41433.1 - 0.00026 19.9 2.3 6.8 5.4 0.0 5.6 5 3 3 8 8 8 1 Prolyl oligopeptidase, N-terminal beta-propeller domain PQQ_3 PF13570.6 KIK41433.1 - 0.0005 20.5 11.4 81 3.9 0.1 9.2 6 3 5 11 11 11 0 PQQ-like domain DUF4402 PF14352.6 KIK41433.1 - 0.00053 20.6 9.9 13 6.4 1.2 6.3 1 1 6 7 7 7 0 Domain of unknown function (DUF4402) AAA_16 PF13191.6 KIK41433.1 - 0.00068 20.1 0.1 0.002 18.5 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain PQQ PF01011.21 KIK41433.1 - 0.0017 18.1 0.0 77 3.5 0.0 6.4 7 0 0 7 7 7 0 PQQ enzyme repeat adh_short_C2 PF13561.6 KIK41433.1 - 0.16 11.5 0.8 0.51 9.8 0.1 2.2 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Torsin PF06309.11 KIK41433.1 - 0.17 12.0 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Torsin Cuticle_4 PF15955.5 KIK41433.1 - 6.8 7.5 14.5 1.2e+02 3.5 0.0 6.7 9 0 0 9 9 7 0 Cuticle protein p450 PF00067.22 KIK41434.1 - 8.7e-58 196.2 0.0 1.3e-57 195.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DFF-C PF09033.10 KIK41434.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain CHAT PF12770.7 KIK41435.1 - 4e-31 108.5 0.0 8.4e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 KIK41435.1 - 1.9e-07 31.2 8.5 0.45 10.8 0.1 7.1 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIK41435.1 - 1.6e-06 27.6 1.0 5 7.1 0.0 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK41435.1 - 2.5e-06 27.1 4.4 4.1 7.7 0.0 8.2 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIK41435.1 - 4.5e-05 23.2 9.3 5 7.1 0.1 7.4 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK41435.1 - 5.7e-05 23.6 15.0 40 5.4 0.0 9.6 10 1 2 12 12 9 0 Tetratricopeptide repeat MIT PF04212.18 KIK41435.1 - 0.00035 20.6 0.2 3.8 7.7 0.0 4.6 3 1 1 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 KIK41435.1 - 0.00042 20.3 0.0 56 4.3 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK41435.1 - 0.00099 18.7 1.1 1.4 8.7 0.0 5.4 7 1 0 7 7 7 1 TPR repeat C2 PF00168.30 KIK41435.1 - 0.0078 16.5 0.0 0.08 13.2 0.0 2.2 2 0 0 2 2 2 1 C2 domain TPR_7 PF13176.6 KIK41435.1 - 0.03 14.3 3.5 18 5.7 0.0 5.2 6 1 0 6 6 5 0 Tetratricopeptide repeat Bac_globin PF01152.21 KIK41435.1 - 0.15 12.2 0.2 36 4.5 0.2 3.6 3 0 0 3 3 3 0 Bacterial-like globin Zeta_toxin PF06414.12 KIK41435.1 - 0.19 11.0 0.0 0.46 9.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DHR10 PF18595.1 KIK41439.1 - 0.0014 18.7 20.2 0.0023 18.0 10.8 2.2 1 1 1 2 2 2 1 Designed helical repeat protein 10 domain TPR_MLP1_2 PF07926.12 KIK41439.1 - 0.017 15.2 19.0 0.23 11.5 6.7 2.1 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KIK41439.1 - 0.033 13.1 9.2 0.043 12.7 9.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4200 PF13863.6 KIK41439.1 - 0.1 13.0 13.4 0.14 12.6 13.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) YscO PF07321.12 KIK41439.1 - 0.15 12.0 21.2 3.8 7.4 14.1 2.2 1 1 1 2 2 2 0 Type III secretion protein YscO LUC7 PF03194.15 KIK41439.1 - 0.16 11.6 8.5 0.19 11.4 7.7 1.4 1 1 0 1 1 1 0 LUC7 N_terminus Fez1 PF06818.15 KIK41439.1 - 0.28 11.6 12.2 0.37 11.2 12.2 1.3 1 0 0 1 1 1 0 Fez1 APG6_N PF17675.1 KIK41439.1 - 0.43 11.1 12.3 0.58 10.7 12.3 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4407 PF14362.6 KIK41439.1 - 0.65 9.3 14.5 0.82 9.0 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 KIK41439.1 - 0.67 10.3 14.7 1.1 9.6 14.0 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Atg14 PF10186.9 KIK41439.1 - 0.79 8.8 14.1 0.67 9.0 13.3 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KIK41439.1 - 1.9 8.5 12.1 6.5 6.8 10.5 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 KIK41439.1 - 2.9 7.0 9.7 2.5 7.3 4.5 2.0 1 1 1 2 2 2 0 TMPIT-like protein COG2 PF06148.11 KIK41439.1 - 7.8 6.6 8.5 16 5.6 5.0 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 LMBR1 PF04791.16 KIK41439.1 - 9.7 5.0 6.5 11 4.8 6.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SMC_N PF02463.19 KIK41440.1 - 1.3e-18 67.3 0.0 1.3e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIK41440.1 - 4.3e-08 33.3 0.0 5.1e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIK41440.1 - 6.6e-08 33.3 0.0 7e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIK41440.1 - 8.5e-08 31.8 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KIK41440.1 - 9.2e-07 28.9 0.0 9.3e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KIK41440.1 - 0.0014 19.2 0.0 0.0015 19.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter DUF2813 PF11398.8 KIK41440.1 - 0.0014 18.0 0.0 0.0016 17.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) AAA_27 PF13514.6 KIK41440.1 - 0.0058 16.3 0.0 0.0064 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KIK41440.1 - 0.099 12.5 0.2 0.13 12.2 0.2 1.3 1 1 0 1 1 1 0 RsgA GTPase Asp_protease_2 PF13650.6 KIK41443.1 - 1.3e-05 25.8 0.0 3.8e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK41443.1 - 8.1e-05 23.1 0.0 0.00027 21.4 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Lipoprotein_21 PF14041.6 KIK41443.1 - 0.12 12.5 0.0 2.6 8.2 0.0 2.3 2 0 0 2 2 2 0 LppP/LprE lipoprotein CENP-R PF06729.12 KIK41444.1 - 0.71 9.8 2.9 1.5 8.8 2.9 1.5 1 0 0 1 1 1 0 Kinetochore component, CENP-R Aldo_ket_red PF00248.21 KIK41445.1 - 7.1e-45 153.5 0.0 7.9e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MarR_2 PF12802.7 KIK41445.1 - 0.15 11.9 0.0 3.1 7.8 0.0 2.8 2 0 0 2 2 2 0 MarR family MFS_1 PF07690.16 KIK41449.1 - 1.8e-38 132.4 30.3 1.8e-38 132.4 30.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK41449.1 - 3.8e-08 32.6 7.3 3.8e-08 32.6 7.3 1.9 3 0 0 3 3 3 1 Sugar (and other) transporter NfrA_C PF13283.6 KIK41450.1 - 0.071 12.6 0.0 0.088 12.3 0.0 1.0 1 0 0 1 1 1 0 Bacteriophage N adsorption protein A C-term O-FucT PF10250.9 KIK41454.1 - 8.6e-13 48.7 0.0 1.1e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Ribosomal_L31 PF01197.18 KIK41455.1 - 0.024 14.9 0.6 1.6 9.0 0.6 2.3 1 1 0 1 1 1 0 Ribosomal protein L31 DPM3 PF08285.11 KIK41456.1 - 5.6e-33 113.0 0.0 6.2e-33 112.9 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Arm_vescicular PF18770.1 KIK41459.1 - 0.032 14.1 0.0 5.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Armadillo tether-repeat of vescicular transport factor 7TM_GPCR_Srb PF02175.16 KIK41462.1 - 0.00079 19.3 5.0 0.0014 18.5 5.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srb MFS_1 PF07690.16 KIK41465.1 - 4.8e-38 131.0 24.3 5.1e-36 124.3 24.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YrhC PF14143.6 KIK41465.1 - 0.23 11.6 0.0 0.23 11.6 0.0 3.6 4 1 0 4 4 4 0 YrhC-like protein DUF4079 PF13301.6 KIK41465.1 - 1.1 9.4 5.9 2.4 8.3 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4079) MFS_1 PF07690.16 KIK41466.1 - 8.6e-39 133.4 23.5 1.4e-38 132.8 23.5 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily WD40 PF00400.32 KIK41467.1 - 5.9e-17 61.7 6.5 7.3e-08 33.0 2.3 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41467.1 - 2.2e-13 50.3 0.3 2.6e-05 24.4 0.2 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KIK41467.1 - 1.9e-05 24.2 0.4 0.006 15.9 0.1 2.9 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK41467.1 - 2.6e-05 23.1 0.1 0.48 9.0 0.0 3.0 2 1 0 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK41467.1 - 7.3e-05 21.9 0.0 0.00044 19.3 0.0 1.9 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 KIK41467.1 - 0.00062 19.6 0.0 7.4 6.7 0.1 3.5 3 0 0 3 3 3 2 PQQ enzyme repeat PD40 PF07676.12 KIK41467.1 - 0.00096 19.0 3.4 1.3 9.1 0.0 3.8 3 1 0 3 3 3 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 KIK41467.1 - 0.0015 18.1 2.6 0.13 11.8 2.6 2.0 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.6 KIK41467.1 - 0.0035 17.8 0.3 2.1 8.9 0.7 2.6 2 1 0 2 2 2 1 PQQ-like domain eIF2A PF08662.11 KIK41467.1 - 0.0045 16.9 0.2 0.015 15.2 0.2 1.8 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KIK41467.1 - 0.012 14.4 0.1 0.14 10.8 0.0 2.0 1 1 1 2 2 2 0 Nup133 N terminal like WD40_like PF17005.5 KIK41467.1 - 0.091 12.1 0.0 4.1 6.6 0.0 2.1 1 1 1 2 2 2 0 WD40-like domain Peroxidase_2 PF01328.17 KIK41470.1 - 2.8e-27 96.5 0.0 3.9e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 RRN9 PF10680.9 KIK41471.1 - 0.054 13.8 0.2 0.54 10.6 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor Hydrolase_6 PF13344.6 KIK41473.1 - 5e-13 49.0 0.0 9e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIK41473.1 - 2.9e-10 40.1 0.0 5.1e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KIK41473.1 - 0.0027 18.0 0.0 0.29 11.4 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-C2H2 PF00096.26 KIK41474.1 - 9.1e-11 41.6 10.1 6.8e-05 23.1 4.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK41474.1 - 2.5e-09 37.2 7.9 0.00062 20.4 2.7 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK41474.1 - 0.00017 21.9 3.2 0.0065 16.8 0.4 4.4 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2HC_2 PF13913.6 KIK41474.1 - 0.0026 17.6 7.6 0.082 12.8 1.4 2.5 2 0 0 2 2 2 2 zinc-finger of a C2HC-type Zn_Tnp_IS1595 PF12760.7 KIK41474.1 - 0.017 15.1 1.1 0.032 14.2 1.1 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-met PF12874.7 KIK41474.1 - 0.024 15.0 1.6 0.052 14.0 0.5 2.3 1 1 0 1 1 1 0 Zinc-finger of C2H2 type DUF1610 PF07754.11 KIK41474.1 - 0.024 14.6 0.1 0.065 13.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) zf-C2H2_jaz PF12171.8 KIK41474.1 - 0.03 14.6 0.3 0.03 14.6 0.3 2.8 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF3268 PF11672.8 KIK41474.1 - 0.063 13.6 0.3 0.11 12.9 0.3 1.3 1 0 0 1 1 1 0 zinc-finger-containing domain CpXC PF14353.6 KIK41474.1 - 0.094 12.8 0.6 2.5 8.1 0.6 2.2 1 1 1 2 2 2 0 CpXC protein Zn_ribbon_SprT PF17283.2 KIK41474.1 - 0.096 12.6 10.4 0.073 13.0 2.4 3.2 2 1 1 3 3 3 0 SprT-like zinc ribbon domain zf-CHCC PF10276.9 KIK41474.1 - 4.4 7.4 6.6 4.7 7.4 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger domain zf-Di19 PF05605.12 KIK41474.1 - 5.4 7.4 7.7 0.93 9.8 2.9 2.3 2 1 0 2 2 1 0 Drought induced 19 protein (Di19), zinc-binding FYDLN_acid PF09538.10 KIK41474.1 - 7.8 7.2 10.0 0.6 10.8 0.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) HhH-GPD PF00730.25 KIK41476.1 - 8.8e-06 26.1 0.0 2.6e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein FH2 PF02181.23 KIK41477.1 - 0.12 11.4 0.4 0.17 11.0 0.4 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain Sec2p PF06428.11 KIK41477.1 - 0.16 12.0 2.8 7 6.7 0.1 2.6 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF4407 PF14362.6 KIK41477.1 - 0.34 10.2 4.2 0.71 9.2 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GATA PF00320.27 KIK41477.1 - 1.2 8.8 3.5 4.7 6.9 0.5 2.3 2 0 0 2 2 2 0 GATA zinc finger zf-HIT PF04438.16 KIK41477.1 - 8.6 6.3 6.3 0.37 10.7 0.6 1.6 2 0 0 2 2 2 0 HIT zinc finger Pkinase_fungal PF17667.1 KIK41481.1 - 7.3e-42 143.6 1.0 6.2e-20 71.4 0.0 3.2 1 1 2 3 3 3 2 Fungal protein kinase Pkinase PF00069.25 KIK41481.1 - 0.0002 20.8 0.0 0.00037 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain LA-virus_coat PF09220.10 KIK41483.1 - 0.056 12.1 0.0 0.073 11.7 0.0 1.1 1 0 0 1 1 1 0 L-A virus, major coat protein WD40 PF00400.32 KIK41485.1 - 3.1e-21 75.3 7.1 3.1e-09 37.3 0.3 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41485.1 - 8.2e-05 22.8 0.0 0.92 9.8 0.0 2.9 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK41485.1 - 0.017 13.8 1.4 0.043 12.5 0.2 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KIK41485.1 - 0.034 12.9 0.1 0.034 12.9 0.1 1.0 1 0 0 1 1 1 0 Nup133 N terminal like AAA_11 PF13086.6 KIK41486.1 - 8.6e-08 32.3 0.2 6.1e-07 29.5 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIK41486.1 - 1.3e-05 25.0 0.0 3.1e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIK41486.1 - 0.00038 20.9 0.0 0.0011 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK41486.1 - 0.001 19.3 0.0 0.0025 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK41486.1 - 0.0022 18.3 0.0 0.01 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KIK41486.1 - 0.0027 17.7 0.0 0.013 15.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA PF00004.29 KIK41486.1 - 0.0041 17.5 0.2 0.011 16.2 0.2 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KIK41486.1 - 0.0064 15.6 0.1 0.015 14.4 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein Rad17 PF03215.15 KIK41486.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain PhoH PF02562.16 KIK41486.1 - 0.011 15.1 0.5 0.51 9.8 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein ATPase_2 PF01637.18 KIK41486.1 - 0.054 13.4 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 KIK41486.1 - 0.056 13.9 2.1 0.53 10.7 0.0 2.7 3 1 0 3 3 3 0 AAA domain NB-ARC PF00931.22 KIK41486.1 - 0.084 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 KIK41486.1 - 0.095 12.9 0.1 0.23 11.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK41486.1 - 0.12 12.1 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_12 PF13087.6 KIK41487.1 - 4.5e-24 85.2 0.4 1.5e-23 83.5 0.4 1.8 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK41487.1 - 3.3e-10 40.2 0.1 3.8e-08 33.4 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KIK41487.1 - 5.8e-05 22.9 0.0 0.00021 21.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KIK41487.1 - 0.0033 17.8 0.0 0.0072 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Retinin_C PF04527.12 KIK41489.1 - 0.12 12.6 0.4 0.29 11.4 0.4 1.7 1 0 0 1 1 1 0 Drosophila Retinin like protein ANAPC4_WD40 PF12894.7 KIK41490.1 - 3.2e-17 62.6 2.2 3.7e-05 24.0 0.0 5.0 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK41490.1 - 2.5e-16 59.8 22.0 5.9e-06 26.9 0.4 6.5 6 1 1 7 7 7 5 WD domain, G-beta repeat Nbas_N PF15492.6 KIK41490.1 - 0.00025 20.5 0.7 1 8.6 0.0 3.5 2 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PQQ PF01011.21 KIK41490.1 - 0.00033 20.5 0.1 0.35 10.9 0.0 3.6 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_3 PF13570.6 KIK41490.1 - 0.0023 18.4 2.6 0.45 11.1 0.2 3.8 4 0 0 4 4 4 1 PQQ-like domain Ge1_WD40 PF16529.5 KIK41490.1 - 0.0061 15.6 0.0 1.6 7.6 0.0 2.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein RAB3GAP2_N PF14655.6 KIK41490.1 - 0.017 14.4 0.1 0.35 10.1 0.0 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40_like PF17005.5 KIK41490.1 - 0.1 11.9 0.0 13 5.0 0.0 2.9 2 1 1 3 3 3 0 WD40-like domain Nup160 PF11715.8 KIK41490.1 - 0.3 9.7 5.8 1.7 7.2 0.4 3.5 3 2 1 4 4 4 0 Nucleoporin Nup120/160 PD40 PF07676.12 KIK41490.1 - 0.52 10.3 5.1 46 4.1 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Exo70 PF03081.15 KIK41491.1 - 1e-05 24.8 0.0 1.2e-05 24.6 0.0 1.0 1 0 0 1 1 1 1 Exo70 exocyst complex subunit MFS_1 PF07690.16 KIK41492.1 - 4.1e-37 127.9 29.6 5.9e-37 127.4 27.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily WSS_VP PF12175.8 KIK41493.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP Mac PF12464.8 KIK41493.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Maltose acetyltransferase Pkinase_fungal PF17667.1 KIK41494.1 - 1.8e-16 59.9 0.1 5.7e-16 58.3 0.0 1.6 1 1 1 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 KIK41494.1 - 0.00036 20.0 0.0 0.00042 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Glyco_hydro_92 PF07971.12 KIK41497.1 - 3e-142 474.8 2.3 3.6e-142 474.5 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KIK41497.1 - 1.7e-61 208.2 3.6 2.6e-61 207.6 3.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain DnaJ PF00226.31 KIK41498.1 - 1.5e-19 69.9 0.3 4.6e-19 68.3 0.1 2.0 2 0 0 2 2 1 1 DnaJ domain TPR_2 PF07719.17 KIK41498.1 - 1.9e-14 52.5 1.3 0.059 13.5 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIK41498.1 - 5e-12 46.1 8.6 0.019 15.4 0.3 6.3 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 KIK41498.1 - 8.3e-11 41.2 0.6 0.00096 18.9 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK41498.1 - 9.2e-09 35.8 10.2 2.8e-05 24.6 0.3 5.4 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIK41498.1 - 1.3e-08 34.9 1.8 0.0067 16.6 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK41498.1 - 6.5e-07 28.9 1.9 3.6 7.8 0.0 5.6 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK41498.1 - 1.1e-06 28.9 9.0 0.68 10.9 0.1 5.9 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIK41498.1 - 2.2e-05 24.1 0.1 0.00018 21.1 0.2 2.4 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 KIK41498.1 - 2.7e-05 24.0 2.5 2.6 8.5 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIK41498.1 - 0.0031 18.0 5.3 15 6.5 0.1 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIK41498.1 - 0.0053 17.0 7.9 4 7.8 0.1 5.8 5 2 1 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK41498.1 - 0.0059 16.8 3.8 10 6.4 0.3 4.8 4 2 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KIK41498.1 - 0.072 13.5 1.4 8 7.1 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Furin-like_2 PF15913.5 KIK41499.1 - 0.015 15.4 0.5 0.027 14.6 0.5 1.4 1 0 0 1 1 1 0 Furin-like repeat, cysteine-rich RVT_1 PF00078.27 KIK41503.1 - 4.9e-06 26.2 0.0 5.1e-06 26.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 KIK41504.1 - 0.001 19.7 0.4 0.0014 19.3 0.4 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase GCHY-1 PF02649.14 KIK41504.1 - 0.14 11.6 0.1 0.14 11.6 0.1 1.1 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 MRP-L47 PF06984.13 KIK41505.1 - 0.081 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) QWRF PF04484.12 KIK41509.1 - 0.0034 17.2 0.7 0.011 15.6 0.2 1.8 2 0 0 2 2 2 1 QWRF family CBFB_NFYA PF02045.15 KIK41510.1 - 1.3e-28 99.3 6.6 1.7e-28 99.0 6.6 1.1 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B HeH PF12949.7 KIK41511.1 - 0.00013 21.6 0.6 0.00024 20.8 0.6 1.4 1 0 0 1 1 1 1 HeH/LEM domain SAP PF02037.27 KIK41511.1 - 0.0024 17.6 2.4 0.078 12.8 0.4 3.1 2 1 0 2 2 2 1 SAP domain Rho_N PF07498.12 KIK41511.1 - 0.021 14.7 1.3 0.021 14.7 1.3 1.9 2 1 0 2 2 2 0 Rho termination factor, N-terminal domain Tho1_MOS11_C PF18592.1 KIK41511.1 - 0.044 13.6 7.2 5.6 6.8 2.0 3.2 1 1 1 2 2 2 0 Tho1/MOS11 C-terminal domain PP2C PF00481.21 KIK41512.1 - 3.9e-29 102.1 0.0 1.1e-28 100.6 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KIK41512.1 - 2.9e-06 27.1 0.0 8.7e-06 25.5 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KIK41512.1 - 0.00039 20.4 0.0 1.1 9.1 0.0 2.6 2 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) DUF4485 PF14846.6 KIK41512.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) UPF0203 PF05254.12 KIK41513.1 - 3.9e-26 91.1 1.4 5.4e-26 90.6 1.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 KIK41513.1 - 0.0021 18.2 3.5 0.59 10.4 0.2 2.2 2 0 0 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.10 KIK41513.1 - 0.024 14.6 0.3 1.6 8.8 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 KIK41513.1 - 0.039 14.3 0.9 0.93 9.9 0.3 2.1 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 KIK41513.1 - 0.18 12.2 0.9 11 6.4 0.3 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 zf-C2H2_2 PF12756.7 KIK41514.1 - 5.1e-37 126.3 11.2 5.3e-31 106.9 0.1 3.2 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KIK41514.1 - 3.3e-10 40.0 12.9 2e-08 34.3 1.7 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIK41514.1 - 2.6e-08 34.0 1.6 2.6e-08 34.0 1.6 2.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KIK41514.1 - 0.0051 17.5 16.6 0.028 15.3 0.1 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK41514.1 - 0.0082 16.6 0.6 0.0082 16.6 0.6 4.4 4 0 0 4 4 4 1 Zinc finger, C2H2 type Rpr2 PF04032.16 KIK41514.1 - 1.1 9.6 4.3 0.55 10.6 1.3 2.2 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-DBF PF07535.12 KIK41514.1 - 2.2 8.5 10.7 0.12 12.5 0.7 3.2 3 0 0 3 3 3 0 DBF zinc finger Rax2 PF12768.7 KIK41515.1 - 8.9e-45 152.8 15.9 3.9e-43 147.4 3.1 5.6 4 1 2 6 6 6 1 Cortical protein marker for cell polarity SH3_1 PF00018.28 KIK41515.1 - 8.9e-08 31.6 0.1 2.1e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK41515.1 - 3.4e-05 23.6 0.5 6.5e-05 22.7 0.5 1.5 1 0 0 1 1 1 1 Variant SH3 domain Kelch_1 PF01344.25 KIK41515.1 - 0.34 10.5 3.9 13 5.5 0.1 4.6 5 0 0 5 5 5 0 Kelch motif DUF5122 PF17164.4 KIK41515.1 - 4.2 7.7 24.9 1.3 9.4 0.0 9.3 9 1 1 10 10 10 0 Domain of unknown function (DUF5122) beta-propeller DUF1279 PF06916.13 KIK41517.1 - 7.3e-18 64.9 0.1 1e-17 64.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) SAM_decarbox PF01536.16 KIK41519.1 - 3.5e-121 404.5 0.0 5.6e-121 403.9 0.0 1.3 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase PP2C PF00481.21 KIK41520.1 - 1.1e-22 80.9 0.0 4.4e-21 75.7 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C eIF-1a PF01176.19 KIK41520.1 - 0.035 13.9 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Zn_clus PF00172.18 KIK41521.1 - 6.2e-09 35.8 27.7 0.00015 21.8 13.1 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Dfp1_Him1_M PF08630.10 KIK41524.1 - 1.8e-31 109.0 0.5 4.2e-31 107.8 0.0 1.9 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 KIK41524.1 - 6.5e-19 67.8 0.2 1.3e-18 66.8 0.2 1.6 1 0 0 1 1 1 1 DBF zinc finger Endothelin PF00322.17 KIK41525.1 - 0.24 11.0 2.4 0.7 9.6 2.4 1.8 1 1 0 1 1 1 0 Endothelin family GCP_C_terminal PF04130.13 KIK41526.1 - 4.7e-60 203.6 0.5 8.8e-60 202.8 0.1 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KIK41526.1 - 6.1e-06 26.1 0.0 3.2e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal UTP15_C PF09384.10 KIK41526.1 - 0.18 11.5 1.5 4.6 6.9 0.0 2.6 2 0 0 2 2 2 0 UTP15 C terminal AAA_22 PF13401.6 KIK41527.1 - 2.4e-12 47.3 0.0 5e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK41527.1 - 1.5e-11 45.0 1.8 7.2e-11 42.8 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA PF00004.29 KIK41527.1 - 4.8e-10 40.0 0.0 1.3e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KIK41527.1 - 8.4e-06 25.3 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein NACHT PF05729.12 KIK41527.1 - 1e-05 25.6 0.1 2.1e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK41527.1 - 1.4e-05 24.5 0.0 2.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.14 KIK41527.1 - 3.5e-05 23.2 0.1 0.065 12.5 0.0 2.3 1 1 1 2 2 2 2 KAP family P-loop domain DUF815 PF05673.13 KIK41527.1 - 5.3e-05 22.5 0.0 0.00025 20.3 0.0 2.0 2 1 1 3 3 3 1 Protein of unknown function (DUF815) DUF2075 PF09848.9 KIK41527.1 - 0.00045 19.6 0.0 0.00071 18.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KIK41527.1 - 0.00048 20.5 0.0 0.0015 18.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KIK41527.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KIK41527.1 - 0.0016 18.2 0.0 0.23 11.2 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein T2SSE PF00437.20 KIK41527.1 - 0.0045 16.1 0.0 0.0083 15.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 KIK41527.1 - 0.0057 16.4 0.3 0.023 14.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain PIF1 PF05970.14 KIK41527.1 - 0.0076 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase Cdc6_C PF09079.11 KIK41527.1 - 0.0077 16.2 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain ATPase_2 PF01637.18 KIK41527.1 - 0.0091 15.9 0.0 0.019 14.9 0.0 1.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 KIK41527.1 - 0.021 14.5 0.0 0.058 13.1 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KIK41527.1 - 0.022 15.1 0.1 0.18 12.2 0.1 2.2 1 1 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 KIK41527.1 - 0.029 14.4 0.1 0.34 10.9 0.1 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KIK41527.1 - 0.047 13.2 0.3 0.17 11.4 0.0 1.9 2 1 0 2 2 2 0 P-loop containing dynein motor region KTI12 PF08433.10 KIK41527.1 - 0.05 13.1 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 KIK41527.1 - 0.13 12.8 0.0 0.34 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Podoplanin PF05808.11 KIK41528.1 - 0.00033 20.8 7.0 0.00078 19.6 7.0 1.6 1 0 0 1 1 1 1 Podoplanin ABC2_membrane_3 PF12698.7 KIK41528.1 - 0.0034 16.5 0.7 0.0054 15.9 0.7 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein Glycophorin_A PF01102.18 KIK41528.1 - 0.0069 16.6 5.9 0.0069 16.6 5.9 2.5 3 1 0 3 3 3 1 Glycophorin A NPR3 PF03666.13 KIK41528.1 - 0.01 14.7 0.7 0.014 14.2 0.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 KIK41528.1 - 0.014 14.2 0.5 0.026 13.3 0.5 1.4 1 0 0 1 1 1 0 Presenilin DUF2207 PF09972.9 KIK41528.1 - 0.17 10.6 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SARAF PF06682.12 KIK41528.1 - 0.27 10.8 0.0 0.27 10.8 0.0 3.0 2 1 1 3 3 2 0 SOCE-associated regulatory factor of calcium homoeostasis AJAP1_PANP_C PF15298.6 KIK41528.1 - 0.33 11.2 15.2 0.056 13.7 11.2 1.7 2 0 0 2 2 2 0 AJAP1/PANP C-terminus CYYR1 PF10873.8 KIK41528.1 - 0.53 10.7 4.5 0.35 11.3 0.5 2.4 2 1 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Plasmodium_Vir PF05795.11 KIK41528.1 - 0.66 9.3 5.9 1.1 8.6 5.9 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SOG2 PF10428.9 KIK41528.1 - 1.6 7.8 42.1 0.25 10.5 12.7 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein NdhL PF10716.9 KIK41529.1 - 0.015 15.3 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit RAP1 PF07218.11 KIK41530.1 - 0.0092 14.3 4.4 0.014 13.8 4.4 1.2 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) SSP160 PF06933.11 KIK41530.1 - 0.67 8.1 13.9 1.1 7.3 13.9 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Glycophorin_A PF01102.18 KIK41532.1 - 0.0012 19.1 1.2 0.0012 19.1 1.2 2.9 2 1 1 3 3 3 1 Glycophorin A DUF3533 PF12051.8 KIK41532.1 - 1.2 8.0 7.0 2 7.2 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Plasmodium_Vir PF05795.11 KIK41532.1 - 1.8 7.9 4.4 3.1 7.1 4.4 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Menin PF05053.13 KIK41532.1 - 3.1 6.0 6.0 4.4 5.5 6.0 1.2 1 0 0 1 1 1 0 Menin TP6A_N PF04406.14 KIK41533.1 - 3.9e-16 58.8 0.0 8.3e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase SprT-like PF10263.9 KIK41533.1 - 0.15 12.0 0.3 0.25 11.2 0.3 1.3 1 0 0 1 1 1 0 SprT-like family WD40 PF00400.32 KIK41534.1 - 7.3e-12 45.6 3.4 0.0015 19.3 0.1 5.5 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41534.1 - 0.0056 16.9 0.0 0.33 11.3 0.0 3.1 1 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK41535.1 - 6.9e-36 121.6 10.7 4e-08 33.8 0.3 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41535.1 - 7.1e-13 48.7 0.1 0.28 11.5 0.0 4.9 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK41535.1 - 1.8e-08 33.7 0.5 9e-05 21.6 0.2 3.0 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 KIK41535.1 - 0.00029 20.0 0.1 0.35 9.9 0.0 3.0 1 1 0 2 2 2 2 Protein of unknown function (DUF1513) PD40 PF07676.12 KIK41535.1 - 0.00068 19.5 0.2 3.7 7.6 0.0 4.5 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK41535.1 - 0.0019 16.9 0.4 0.15 10.7 0.0 2.8 2 1 0 3 3 3 1 Nucleoporin Nup120/160 Lactonase PF10282.9 KIK41535.1 - 0.004 16.5 0.0 0.085 12.1 0.0 2.6 1 1 1 2 2 2 1 Lactonase, 7-bladed beta-propeller Nucleoporin_N PF08801.11 KIK41535.1 - 0.011 14.5 0.5 0.083 11.6 0.2 2.1 1 1 0 2 2 2 0 Nup133 N terminal like Nbas_N PF15492.6 KIK41535.1 - 0.061 12.7 0.2 1.5 8.1 0.0 2.8 1 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK41535.1 - 0.1 11.9 0.0 3 7.1 0.0 2.6 3 0 0 3 3 3 0 WD40-like domain Ribonuclease_3 PF00636.26 KIK41537.1 - 1.3e-42 144.6 0.0 8.7e-21 74.5 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KIK41537.1 - 5.8e-27 94.4 0.3 2.1e-14 53.8 0.0 3.8 2 2 0 2 2 2 2 Ribonuclease-III-like ResIII PF04851.15 KIK41537.1 - 1.7e-16 60.7 0.1 3e-16 59.9 0.1 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIK41537.1 - 1.1e-15 57.9 0.0 2.5e-14 53.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK41537.1 - 3.5e-15 56.2 0.0 6.2e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Dicer_dimer PF03368.14 KIK41537.1 - 2.8e-14 53.0 0.0 6.7e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain SWI2_SNF2 PF18766.1 KIK41537.1 - 1.4e-05 24.9 0.0 3.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase SNF2_N PF00176.23 KIK41537.1 - 0.016 14.0 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain RRM_1 PF00076.22 KIK41538.1 - 6.7e-34 115.5 0.0 5.2e-18 64.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Knl1_RWD_C PF18210.1 KIK41539.1 - 0.18 12.3 0.0 4.1 7.9 0.0 2.1 1 1 1 2 2 2 0 Knl1 RWD C-terminal domain Amidohydro_3 PF07969.11 KIK41541.1 - 4.9e-15 56.0 0.0 2.8e-06 27.1 0.0 2.6 2 1 1 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 KIK41541.1 - 5.4e-13 49.0 0.0 5.6e-09 35.8 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family PD40 PF07676.12 KIK41541.1 - 9e-08 31.9 0.0 0.0054 16.6 0.0 4.4 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat BORG_CEP PF14957.6 KIK41542.1 - 2 9.6 6.4 0.21 12.8 1.4 1.8 2 1 0 2 2 2 0 Cdc42 effector eRF1_2 PF03464.15 KIK41543.1 - 3.2e-47 160.2 0.0 5.8e-47 159.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KIK41543.1 - 4.9e-38 130.1 0.1 1e-37 129.0 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KIK41543.1 - 1.6e-19 70.1 0.0 3e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 KIK41543.1 - 2.9e-11 43.8 0.1 4.6e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 KIK41543.1 - 6.7e-08 32.9 0.0 1.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Rpp20 PF12328.8 KIK41544.1 - 3.3e-09 36.8 1.6 3.2e-08 33.6 0.0 2.6 2 1 1 3 3 3 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KIK41544.1 - 0.00032 20.5 0.0 0.00059 19.6 0.0 1.5 1 0 0 1 1 1 1 Alba Mis12 PF05859.12 KIK41546.1 - 9.6e-41 139.0 0.5 1.7e-40 138.2 0.5 1.4 1 0 0 1 1 1 1 Mis12 protein Lzipper-MIP1 PF14389.6 KIK41546.1 - 0.0035 17.6 3.0 0.0094 16.2 3.0 1.8 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 FLILHELTA PF10306.9 KIK41554.1 - 0.079 13.4 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 Hypothetical protein FLILHELTA NLE PF08154.12 KIK41557.1 - 6.7e-16 58.6 0.0 1.3e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 KIK41557.1 - 7.7e-13 48.7 14.5 0.087 13.7 2.2 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 KIK41557.1 - 0.012 14.2 0.7 4 6.0 0.0 2.8 3 1 1 4 4 4 0 Nucleoporin Nup120/160 SLC3A2_N PF16028.5 KIK41559.1 - 0.024 14.2 0.6 0.033 13.7 0.6 1.3 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus N1221 PF07923.13 KIK41559.1 - 0.075 12.2 0.0 0.075 12.2 0.0 1.0 1 0 0 1 1 1 0 N1221-like protein DUF1751 PF08551.10 KIK41560.1 - 6.2 7.5 12.2 0.14 12.7 1.7 2.7 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) MCM3AP_GANP PF16769.5 KIK41561.1 - 0.1 10.8 0.1 0.1 10.8 0.1 1.0 1 0 0 1 1 1 0 MCM3AP domain of GANP Pkinase_fungal PF17667.1 KIK41562.1 - 0.00015 20.7 0.3 0.00017 20.5 0.3 1.0 1 0 0 1 1 1 1 Fungal protein kinase zf-Di19 PF05605.12 KIK41564.1 - 0.094 13.0 5.3 0.15 12.4 1.4 2.4 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KIK41568.1 - 1.1e-21 75.6 27.3 0.015 16.1 0.3 7.3 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK41568.1 - 1.7e-17 62.8 34.2 0.0013 19.1 0.7 7.3 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KIK41568.1 - 3.3e-16 59.1 18.9 0.008 16.4 0.1 7.2 6 1 1 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIK41568.1 - 5.7e-12 45.6 19.4 0.00045 20.5 0.3 6.7 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KIK41568.1 - 1.8e-10 40.5 26.2 0.00045 20.1 0.9 6.3 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KIK41568.1 - 1.4e-09 38.2 18.5 0.0079 16.5 0.4 6.1 2 2 3 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KIK41568.1 - 0.0063 16.3 18.0 8.5 6.3 0.1 6.2 5 2 2 7 7 7 0 C2H2 type zinc-finger (1 copy) zf-H2C2_2 PF13465.6 KIK41568.1 - 0.0079 16.6 0.2 0.0079 16.6 0.2 6.5 8 0 0 8 8 5 3 Zinc-finger double domain zf-C2H2_11 PF16622.5 KIK41568.1 - 0.014 15.2 17.3 13 5.6 0.1 6.1 6 0 0 6 6 6 0 zinc-finger C2H2-type OSTMP1 PF09777.9 KIK41568.1 - 0.022 14.2 8.7 0.26 10.6 0.1 3.4 2 2 1 3 3 3 0 Osteopetrosis-associated transmembrane protein 1 precursor Rad50_zn_hook PF04423.14 KIK41568.1 - 0.029 14.2 7.0 2.9 7.8 0.0 4.3 4 0 0 4 4 4 0 Rad50 zinc hook motif zf-C2H2_8 PF15909.5 KIK41568.1 - 0.033 14.5 15.5 2.8 8.3 1.2 3.5 3 1 1 4 4 4 0 C2H2-type zinc ribbon Cytomega_UL84 PF06284.11 KIK41568.1 - 0.085 11.3 1.0 0.096 11.1 0.2 1.4 2 0 0 2 2 2 0 Cytomegalovirus UL84 protein zf-Di19 PF05605.12 KIK41568.1 - 0.1 12.9 0.1 0.1 12.9 0.1 5.2 5 2 1 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding CENP-B_dimeris PF09026.10 KIK41568.1 - 0.11 12.9 9.7 0.25 11.7 9.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-C2HC_2 PF13913.6 KIK41568.1 - 0.12 12.4 0.4 0.12 12.4 0.4 5.9 7 0 0 7 7 5 0 zinc-finger of a C2HC-type DUF3039 PF11238.8 KIK41568.1 - 0.15 11.9 6.0 5 7.0 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3039) Zn-C2H2_12 PF18112.1 KIK41568.1 - 0.18 12.3 5.9 0.53 10.8 0.4 3.7 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2HE PF16278.5 KIK41568.1 - 0.21 12.1 18.8 14 6.2 0.3 5.2 4 1 1 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger PBP1_TM PF14812.6 KIK41568.1 - 0.22 11.9 7.3 0.41 11.1 7.3 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1033 PF06279.11 KIK41568.1 - 0.28 11.4 4.0 0.22 11.7 0.8 2.3 3 0 0 3 3 2 0 Protein of unknown function (DUF1033) Cwf_Cwc_15 PF04889.12 KIK41568.1 - 0.35 10.6 7.3 0.47 10.1 7.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Spt46 PF17734.1 KIK41568.1 - 0.41 10.4 9.9 3.9 7.2 1.8 4.3 3 2 2 5 5 5 0 Spermatogenesis-associated protein 46 zf_C2H2_ZHX PF18387.1 KIK41568.1 - 0.64 9.7 0.1 0.64 9.7 0.1 5.0 5 1 1 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain DNA_pol_phi PF04931.13 KIK41568.1 - 3.4 5.6 6.7 4.8 5.2 6.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi FOXP-CC PF16159.5 KIK41568.1 - 5.5 7.7 13.6 33 5.2 0.1 5.0 4 2 1 5 5 5 0 FOXP coiled-coil domain Dynamin_M PF01031.20 KIK41569.1 - 1.3e-101 339.6 0.0 2.2e-101 338.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KIK41569.1 - 3.3e-54 183.4 0.0 7.3e-54 182.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KIK41569.1 - 1.6e-28 98.7 2.2 1.6e-28 98.7 2.2 1.7 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIK41569.1 - 0.00015 21.8 0.1 0.0011 19.0 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KIK41569.1 - 0.13 12.0 0.2 16 5.1 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain NTF2 PF02136.20 KIK41570.1 - 1e-29 103.5 0.1 1.1e-29 103.4 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 KIK41570.1 - 0.017 15.1 0.0 0.019 14.9 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 DUF4440 PF14534.6 KIK41570.1 - 0.099 13.1 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SLT_L PF14718.6 KIK41571.1 - 0.038 14.1 0.0 0.076 13.2 0.0 1.4 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain zf-C3HC4_3 PF13920.6 KIK41572.1 - 1.7e-06 27.8 13.8 1.3e-05 24.9 10.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK41572.1 - 3.1e-06 26.9 11.4 3.1e-06 26.9 11.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK41572.1 - 3.9e-06 26.8 9.7 3.9e-06 26.8 9.7 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIK41572.1 - 3.9e-06 26.6 16.7 4.5e-06 26.4 12.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK41572.1 - 8.3e-06 26.0 12.4 8.3e-06 26.0 12.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KIK41572.1 - 2.7e-05 24.0 15.7 5.1e-05 23.1 11.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_10 PF16685.5 KIK41572.1 - 2.8e-05 24.1 3.9 5.8e-05 23.2 3.9 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KIK41572.1 - 8.5e-05 22.3 12.7 0.0037 17.1 10.7 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KIK41572.1 - 0.00015 21.8 13.6 0.00015 21.8 13.6 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KIK41572.1 - 0.0016 18.3 5.9 0.0016 18.3 5.9 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein U-box PF04564.15 KIK41572.1 - 0.0023 18.0 0.0 0.0089 16.2 0.0 2.0 2 0 0 2 2 1 1 U-box domain SAP PF02037.27 KIK41572.1 - 0.0024 17.6 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 1 SAP domain UBA2_C PF16195.5 KIK41572.1 - 0.02 15.6 1.1 0.02 15.6 1.1 3.4 4 1 0 4 4 4 0 SUMO-activating enzyme subunit 2 C-terminus zf-rbx1 PF12678.7 KIK41572.1 - 0.03 14.6 6.4 0.03 14.6 6.4 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain Alginate_lyase2 PF08787.11 KIK41572.1 - 0.04 13.8 0.1 0.059 13.2 0.1 1.2 1 0 0 1 1 1 0 Alginate lyase Tmemb_55A PF09788.9 KIK41572.1 - 0.14 11.2 8.3 0.2 10.7 2.9 2.3 2 0 0 2 2 2 0 Transmembrane protein 55A zf-H2C2_2 PF13465.6 KIK41572.1 - 2.9 8.5 5.7 6.4 7.4 0.7 3.5 3 1 0 3 3 3 0 Zinc-finger double domain TRAF6_Z2 PF18048.1 KIK41572.1 - 4.6 7.4 8.3 1.5 9.0 0.1 2.8 2 1 1 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 DUF1195 PF06708.11 KIK41576.1 - 0.098 12.4 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) Myosin_head PF00063.21 KIK41579.1 - 2e-95 320.5 0.0 4e-95 319.5 0.0 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DUF3564 PF12087.8 KIK41580.1 - 0.086 12.8 0.0 0.093 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3564) DUF2080 PF09853.9 KIK41582.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative transposon-encoded protein (DUF2080) Mlf1IP PF10248.9 KIK41583.1 - 1.1 9.2 7.7 0.23 11.4 2.4 2.1 2 0 0 2 2 2 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein NotI PF12183.8 KIK41584.1 - 0.2 11.0 0.2 0.22 10.8 0.2 1.1 1 0 0 1 1 1 0 Restriction endonuclease NotI adh_short PF00106.25 KIK41585.1 - 2.7e-17 62.9 0.0 2.7e-15 56.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK41585.1 - 7.3e-08 32.2 0.0 4.2e-07 29.8 0.0 2.0 2 1 1 3 3 3 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK41585.1 - 0.00012 22.1 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 KR domain p450 PF00067.22 KIK41586.1 - 1.1e-70 238.7 0.0 1.4e-70 238.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Bax1-I PF01027.20 KIK41587.1 - 4.8e-45 153.9 26.3 5.6e-45 153.7 26.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF308 PF03729.13 KIK41587.1 - 5.3 7.4 21.6 0.17 12.2 3.1 3.2 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) WD40 PF00400.32 KIK41589.1 - 3e-24 84.8 16.3 3.7e-07 30.7 1.1 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41589.1 - 4.7e-18 65.3 0.1 0.00057 20.1 0.0 5.7 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KIK41589.1 - 0.0029 18.1 0.3 74 4.0 0.0 4.9 4 0 0 4 4 4 0 PQQ-like domain TFIIIC_delta PF12657.7 KIK41589.1 - 0.0045 16.9 0.4 0.034 14.1 0.0 2.5 2 1 0 2 2 2 1 Transcription factor IIIC subunit delta N-term Ge1_WD40 PF16529.5 KIK41589.1 - 0.17 10.8 0.0 58 2.5 0.0 3.3 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_5 PF07728.14 KIK41590.1 - 0.0003 20.8 0.4 0.00084 19.3 0.0 2.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KIK41590.1 - 0.0009 18.5 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA PF00004.29 KIK41590.1 - 0.0016 18.9 0.0 0.0029 18.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Crr6 PF08847.11 KIK41590.1 - 0.081 12.6 0.0 0.49 10.0 0.0 2.1 1 1 2 3 3 3 0 Chlororespiratory reduction 6 CAP-ZIP_m PF15255.6 KIK41592.1 - 0.034 14.4 1.1 0.034 14.4 1.1 1.1 1 0 0 1 1 1 0 WASH complex subunit CAP-Z interacting, central region WD40 PF00400.32 KIK41593.1 - 7.1e-43 143.8 15.4 1.7e-07 31.8 0.4 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41593.1 - 5.3e-24 84.3 1.7 1.9e-05 24.9 0.1 7.0 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK41593.1 - 1.1e-07 31.1 0.0 0.068 12.1 0.0 4.3 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK41593.1 - 2.2e-06 26.6 5.0 2.6 6.6 0.0 5.5 1 1 5 6 6 6 3 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK41593.1 - 7.9e-05 22.1 0.3 0.007 15.7 0.0 3.5 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 KIK41593.1 - 0.00022 21.1 0.0 0.0025 17.7 0.0 2.4 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK41593.1 - 0.00042 19.7 0.0 0.81 8.9 0.0 3.4 2 1 1 3 3 3 1 WD40-like domain PD40 PF07676.12 KIK41593.1 - 0.0016 18.3 0.0 29 4.7 0.0 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK41593.1 - 0.03 12.7 0.0 2.9 6.1 0.0 2.4 2 1 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Lactonase PF10282.9 KIK41593.1 - 0.035 13.3 0.0 2.3 7.4 0.0 2.3 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller DUF5046 PF16465.5 KIK41593.1 - 0.11 12.0 0.0 11 5.4 0.0 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF5046) PALB2_WD40 PF16756.5 KIK41593.1 - 0.28 10.1 1.5 17 4.2 0.0 2.6 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain PHZA_PHZB PF03284.13 KIK41593.1 - 1.4 8.5 3.5 3.5 7.2 0.0 2.9 2 1 2 4 4 4 0 Phenazine biosynthesis protein A/B zinc_ribbon_16 PF17034.5 KIK41595.1 - 7.1e-15 55.3 11.2 3.4e-14 53.1 9.3 2.9 2 1 0 2 2 2 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 KIK41595.1 - 0.00032 20.3 5.6 0.00032 20.3 5.6 2.6 3 1 0 3 3 3 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KIK41595.1 - 0.0011 19.7 6.9 6.2 7.9 0.1 6.0 6 0 0 6 6 6 1 WD domain, G-beta repeat TPR_MalT PF17874.1 KIK41596.1 - 0.053 12.9 0.2 0.078 12.3 0.2 1.2 1 0 0 1 1 1 0 MalT-like TPR region SPX PF03105.19 KIK41596.1 - 2.8 7.8 7.4 4.2 7.2 7.4 1.2 1 0 0 1 1 1 0 SPX domain WD40 PF00400.32 KIK41597.1 - 2e-33 113.9 14.7 0.00025 21.8 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41597.1 - 1.4e-14 54.1 1.2 0.00054 20.2 0.0 5.9 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK41597.1 - 5.2e-09 35.5 0.2 0.028 13.4 0.0 3.8 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK41597.1 - 5.6e-06 25.3 0.5 0.068 11.8 0.0 3.4 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK41597.1 - 0.0018 17.7 0.3 1.4 8.2 0.0 4.1 2 2 2 5 5 5 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KIK41597.1 - 0.015 15.3 0.3 17 5.5 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK41597.1 - 0.053 12.8 0.0 1.4 8.2 0.0 3.0 4 1 1 5 5 5 0 WD40-like domain HSP70 PF00012.20 KIK41598.1 - 4.5e-160 533.7 0.4 9.9e-160 532.6 0.0 1.7 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KIK41598.1 - 1.1e-12 47.4 0.2 3.6e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein Actin PF00022.19 KIK41598.1 - 0.0021 16.8 0.1 2.5 6.6 0.0 3.0 2 1 0 3 3 3 2 Actin Raco_middle PF17651.1 KIK41598.1 - 0.043 13.5 0.2 9.1 5.9 0.0 3.1 3 0 0 3 3 3 0 RACo middle region Dyp_perox PF04261.12 KIK41598.1 - 0.061 12.3 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Dyp-type peroxidase family DUF3915 PF13054.6 KIK41599.1 - 0.53 10.3 6.3 1.8 8.5 6.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) R3H PF01424.22 KIK41600.1 - 2.4e-14 53.0 0.0 5.9e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KIK41600.1 - 4.9e-07 29.5 3.0 8.7e-07 28.7 0.0 2.5 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KIK41600.1 - 0.00098 19.2 0.2 0.0045 17.1 0.2 2.2 1 0 0 1 1 1 1 G-patch domain WD40 PF00400.32 KIK41601.1 - 1.3e-31 108.2 12.0 2.1e-07 31.5 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41601.1 - 6.6e-16 58.4 2.2 3.6e-05 24.0 0.0 5.9 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK41601.1 - 5.8e-07 29.6 0.0 0.00036 20.5 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK41601.1 - 2.9e-06 26.5 0.8 0.0068 15.4 0.1 3.3 2 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK41601.1 - 3.7e-05 22.6 4.7 0.95 8.0 0.0 4.9 4 2 1 5 5 5 2 Nucleoporin Nup120/160 PQQ PF01011.21 KIK41601.1 - 0.02 14.8 1.3 7.1 6.8 0.1 3.8 4 0 0 4 4 4 0 PQQ enzyme repeat PD40 PF07676.12 KIK41601.1 - 0.12 12.3 0.1 1e+02 3.0 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK41601.1 - 0.15 11.4 0.0 3.7 6.8 0.0 2.6 2 1 1 3 3 3 0 WD40-like domain RasGEF PF00617.19 KIK41604.1 - 9.9e-15 55.2 0.0 4.3e-14 53.1 0.0 2.2 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KIK41604.1 - 1.3e-14 54.3 0.4 8.9e-14 51.6 0.1 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif WD40 PF00400.32 KIK41606.1 - 3.2e-13 49.9 0.1 1.9e-05 25.3 0.0 2.0 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41606.1 - 0.00044 20.5 0.0 0.021 15.1 0.0 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK41606.1 - 0.0034 16.4 0.0 0.0045 16.0 0.0 1.2 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KIK41607.1 - 1.5e-09 38.0 0.1 1.2e-05 25.5 0.0 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK41607.1 - 3.2e-07 30.9 0.0 0.0041 17.9 0.0 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40_like PF17005.5 KIK41607.1 - 0.0067 15.8 0.0 0.0071 15.7 0.0 1.1 1 0 0 1 1 1 1 WD40-like domain Cytochrom_D1 PF02239.16 KIK41607.1 - 0.011 14.3 0.0 0.011 14.3 0.0 1.0 1 0 0 1 1 1 0 Cytochrome D1 heme domain PQQ PF01011.21 KIK41607.1 - 0.039 13.9 0.1 0.14 12.1 0.0 2.0 3 0 0 3 3 3 0 PQQ enzyme repeat Me-amine-dh_H PF06433.11 KIK41607.1 - 0.064 12.1 0.0 0.064 12.1 0.0 1.1 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) Frtz PF11768.8 KIK41607.1 - 0.085 11.1 0.0 0.085 11.1 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 KIK41607.1 - 0.098 12.5 0.0 0.18 11.6 0.0 1.4 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Plavaka PF18759.1 KIK41608.1 - 3.4e-42 144.8 0.8 5.7e-21 75.1 0.0 2.2 1 1 1 2 2 2 2 Plavaka transposase DUF1676 PF07898.13 KIK41608.1 - 0.14 12.2 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) DUF4287 PF14117.6 KIK41609.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) p450 PF00067.22 KIK41610.1 - 3.9e-69 233.6 0.0 4.6e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Toxin_12 PF07740.12 KIK41611.1 - 0.12 13.1 6.3 0.26 12.0 6.3 1.6 1 0 0 1 1 1 0 Ion channel inhibitory toxin D_CNTX PF17492.2 KIK41611.1 - 0.24 11.6 8.1 0.41 10.9 8.1 1.3 1 0 0 1 1 1 0 Delta Ctenitoxins Bestrophin PF01062.21 KIK41613.1 - 2.4e-33 115.8 3.8 7.3e-21 74.8 0.0 2.5 2 1 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel PetG PF02529.15 KIK41614.1 - 0.04 13.8 0.0 8.9 6.3 0.1 2.4 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 Bestrophin PF01062.21 KIK41616.1 - 2.2e-34 119.2 0.6 1.6e-22 80.2 0.1 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel ABC2_membrane_5 PF13346.6 KIK41616.1 - 0.057 13.0 1.5 0.87 9.1 0.2 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein PrgI PF12666.7 KIK41616.1 - 0.12 13.1 0.2 0.46 11.2 0.1 2.0 2 0 0 2 2 2 0 PrgI family protein Mem_trans PF03547.18 KIK41617.1 - 2.7e-21 75.4 9.8 7.5e-21 74.0 9.8 1.6 1 1 0 1 1 1 1 Membrane transport protein F-box-like PF12937.7 KIK41618.1 - 3e-06 27.0 1.6 7.6e-06 25.7 1.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK41618.1 - 6.8e-05 22.6 1.0 0.00015 21.5 1.0 1.6 1 0 0 1 1 1 1 F-box domain NPH3 PF03000.14 KIK41618.1 - 0.057 13.1 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 NPH3 family Glyco_hydro_61 PF03443.14 KIK41619.1 - 1.6e-52 178.5 0.0 2e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 IBR PF01485.21 KIK41622.1 - 1.8e-08 34.5 20.2 6.8e-05 23.0 2.8 3.0 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KIK41622.1 - 0.0002 21.2 2.4 0.0002 21.2 2.4 3.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK41622.1 - 0.00031 21.0 3.6 0.00031 21.0 3.6 4.5 2 2 2 4 4 4 1 Ring finger domain zf-RING_11 PF17123.5 KIK41622.1 - 0.00033 20.3 1.4 0.00033 20.3 1.4 4.5 4 1 0 4 4 4 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KIK41622.1 - 0.00056 19.9 4.7 0.00056 19.9 4.7 3.3 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIK41622.1 - 0.00071 19.4 0.4 0.00071 19.4 0.4 3.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIK41622.1 - 0.044 14.1 1.7 0.044 14.1 1.7 3.9 2 2 0 2 2 2 0 RING-H2 zinc finger domain zinc_ribbon_4 PF13717.6 KIK41622.1 - 2.3 8.2 0.0 2.3 8.2 0.0 4.2 5 0 0 5 5 5 0 zinc-ribbon domain Methyltransf_2 PF00891.18 KIK41623.1 - 9.6e-09 34.8 0.0 0.00044 19.6 0.0 3.4 3 0 0 3 3 3 3 O-methyltransferase domain PCMT PF01135.19 KIK41623.1 - 0.032 14.0 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MMR_HSR1 PF01926.23 KIK41625.1 - 1.4e-05 25.1 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KIK41625.1 - 0.00029 20.3 0.0 0.00069 19.1 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KIK41625.1 - 0.0012 19.1 0.0 0.0048 17.1 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KIK41625.1 - 0.0018 17.8 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain G-alpha PF00503.20 KIK41625.1 - 0.014 14.6 0.2 0.32 10.1 0.0 2.4 2 1 0 2 2 2 0 G-protein alpha subunit TniB PF05621.11 KIK41625.1 - 0.021 14.3 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 KIK41625.1 - 0.022 14.7 0.0 5.9 6.8 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 KIK41625.1 - 0.047 13.4 0.0 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ADSL_C PF10397.9 KIK41625.1 - 0.066 13.8 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus ATP-synt_ab PF00006.25 KIK41625.1 - 0.074 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.18 KIK41625.1 - 0.08 12.2 0.0 1.4 8.1 0.0 2.0 2 0 0 2 2 2 0 Septin FeoB_N PF02421.18 KIK41625.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 KIK41625.1 - 0.17 11.7 0.0 7.7 6.2 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KIK41625.1 - 0.19 11.4 0.0 0.37 10.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain Cellulase PF00150.18 KIK41626.1 - 7.1e-14 51.9 0.1 2.8e-13 50.0 0.1 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ribosomal_L18_c PF14204.6 KIK41629.1 - 0.066 14.2 0.0 0.35 11.9 0.0 2.2 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region MFS_1 PF07690.16 KIK41632.1 - 1e-39 136.5 23.8 1e-39 136.5 23.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK41632.1 - 2.6e-08 33.2 19.4 3.6e-08 32.7 19.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter NrsF PF06532.11 KIK41632.1 - 0.024 14.4 0.3 0.024 14.4 0.3 2.9 3 1 1 4 4 4 0 Negative regulator of sigma F Calreticulin PF00262.18 KIK41633.1 - 3.8e-158 526.2 7.1 5e-158 525.8 7.1 1.1 1 0 0 1 1 1 1 Calreticulin family GTP_EFTU PF00009.27 KIK41634.1 - 1.8e-46 158.2 0.1 2.9e-46 157.4 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KIK41634.1 - 1.2e-37 129.1 4.8 2e-37 128.5 4.8 1.3 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KIK41634.1 - 5.8e-23 81.0 0.0 1.2e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KIK41634.1 - 1.8e-21 76.0 0.0 3.9e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KIK41634.1 - 3.1e-09 37.1 0.0 6.6e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIK41634.1 - 8.3e-06 25.9 0.1 1.6e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 KIK41634.1 - 1.2e-05 25.3 0.0 3.3e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 KIK41634.1 - 0.003 17.0 0.1 0.0065 15.9 0.1 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 KIK41634.1 - 0.03 14.4 0.1 2.6 8.1 0.2 2.5 1 1 1 2 2 2 0 Dynamin family Ras PF00071.22 KIK41634.1 - 0.077 12.6 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Ras family Prefoldin_2 PF01920.20 KIK41635.1 - 1.5e-15 57.1 8.4 1.8e-15 56.8 8.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit Mei5 PF10376.9 KIK41635.1 - 0.0054 16.6 4.1 0.0065 16.4 4.1 1.1 1 0 0 1 1 1 1 Double-strand recombination repair protein DHR10 PF18595.1 KIK41635.1 - 0.025 14.6 7.9 0.076 13.1 0.8 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF5320 PF17253.2 KIK41635.1 - 0.041 14.9 1.6 0.081 14.0 0.4 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5320) FAM91_C PF14648.6 KIK41635.1 - 0.067 12.0 2.3 0.076 11.8 2.3 1.0 1 0 0 1 1 1 0 FAM91 C-terminus MRP-L51 PF10244.9 KIK41635.1 - 0.068 13.4 0.3 0.13 12.5 0.3 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit DNA_repr_REX1B PF14966.6 KIK41635.1 - 0.16 12.7 0.2 0.16 12.7 0.2 2.1 1 1 1 2 2 2 0 DNA repair REX1-B CorA PF01544.18 KIK41635.1 - 0.18 11.1 3.2 2.7 7.2 0.4 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Tropomyosin_1 PF12718.7 KIK41635.1 - 0.33 11.1 9.1 0.06 13.5 3.3 2.0 1 1 0 1 1 1 0 Tropomyosin like DUF4200 PF13863.6 KIK41635.1 - 0.37 11.2 11.3 0.33 11.3 3.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) MFS_1 PF07690.16 KIK41636.1 - 1.6e-17 63.5 31.2 2.5e-17 62.9 31.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily PBP_N PF17093.5 KIK41637.1 - 1.8 8.8 3.4 0.83 9.9 0.2 2.0 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus EF-hand_6 PF13405.6 KIK41638.1 - 1.9e-10 39.8 0.4 0.0002 21.0 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KIK41638.1 - 1.8e-07 30.4 0.2 0.00074 18.9 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KIK41638.1 - 4.4e-07 30.2 1.0 1.1e-06 28.9 1.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KIK41638.1 - 4.2e-06 25.9 0.3 0.002 17.5 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KIK41638.1 - 0.0016 18.3 0.4 0.027 14.3 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair CECR6_TMEM121 PF14997.6 KIK41638.1 - 0.3 10.9 0.5 0.64 9.8 0.1 1.6 2 0 0 2 2 2 0 CECR6/TMEM121 family Dopey_N PF04118.14 KIK41639.1 - 5.7e-109 363.9 0.2 2.5e-108 361.8 0.0 2.2 2 0 0 2 2 2 1 Dopey, N-terminal GFA PF04828.14 KIK41641.1 - 6e-11 42.5 0.9 9.5e-11 41.9 0.9 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme ATP-synt_E PF05680.12 KIK41642.1 - 1.8e-18 66.6 0.1 2e-18 66.5 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain CAF1C_H4-bd PF12265.8 KIK41643.1 - 6.5e-30 103.2 0.6 1.8e-29 101.8 0.6 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KIK41643.1 - 3.5e-17 62.5 14.6 1.3e-05 25.9 0.2 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Frtz PF11768.8 KIK41643.1 - 0.003 15.9 0.0 0.0042 15.5 0.0 1.2 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 KIK41643.1 - 0.012 15.5 0.0 0.036 13.9 0.0 1.8 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A RAMP4 PF06624.12 KIK41644.1 - 3.7e-13 49.3 0.1 4.1e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF3040 PF11239.8 KIK41644.1 - 0.016 15.5 0.1 0.017 15.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) p450 PF00067.22 KIK41645.1 - 2.6e-60 204.5 0.0 2.9e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transposase_21 PF02992.14 KIK41646.1 - 1.5e-06 27.6 0.0 3.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 KIK41646.1 - 0.076 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) zf-H2C2_2 PF13465.6 KIK41650.1 - 0.0022 18.4 3.3 0.0048 17.3 3.3 1.6 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK41650.1 - 0.057 14.3 4.7 0.14 13.1 2.6 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK41650.1 - 1.9 8.9 7.2 5.2 7.5 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KIK41650.1 - 3.5 8.3 8.0 3.6 8.2 3.5 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type WD40 PF00400.32 KIK41652.1 - 1.1e-20 73.6 6.2 4.4e-05 24.2 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41652.1 - 0.00044 20.5 0.0 0.14 12.4 0.0 3.8 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2793 PF10983.8 KIK41652.1 - 0.18 11.7 0.2 0.53 10.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2793) PIG-P PF08510.12 KIK41653.1 - 0.042 13.8 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 PIG-P MerC PF03203.14 KIK41653.1 - 1.2 9.6 4.2 3 8.3 0.2 2.0 1 1 1 2 2 2 0 MerC mercury resistance protein WD40 PF00400.32 KIK41657.1 - 2.5e-17 62.9 9.4 0.00052 20.8 0.0 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41657.1 - 0.00097 19.4 0.0 0.051 13.9 0.0 3.2 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK41657.1 - 0.0016 18.4 0.4 25 5.0 0.0 4.9 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KIK41657.1 - 0.037 12.5 0.1 0.074 11.6 0.1 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain p450 PF00067.22 KIK41659.1 - 1.3e-64 218.7 0.0 1.5e-64 218.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Thionin PF00321.17 KIK41660.1 - 1.3 9.6 0.1 1.3 9.6 0.1 2.4 3 0 0 3 3 3 0 Plant thionin DUF2431 PF10354.9 KIK41661.1 - 8.8e-51 172.5 0.0 1.3e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) DUF3886 PF13025.6 KIK41661.1 - 0.32 11.2 4.8 0.57 10.4 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) DASH_Spc19 PF08287.11 KIK41661.1 - 0.64 9.9 5.1 0.2 11.5 2.2 1.6 2 0 0 2 2 2 0 Spc19 NrsF PF06532.11 KIK41662.1 - 0.0052 16.5 0.1 0.009 15.8 0.1 1.3 1 0 0 1 1 1 1 Negative regulator of sigma F Adeno_E3 PF06040.11 KIK41662.1 - 0.075 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 protein Fip1 PF05182.13 KIK41663.1 - 1.1e-20 72.9 0.4 1.7e-20 72.3 0.4 1.3 1 0 0 1 1 1 1 Fip1 motif adh_short PF00106.25 KIK41664.1 - 1.7e-28 99.4 0.4 2.6e-28 98.8 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK41664.1 - 2e-22 79.9 0.2 2.4e-22 79.6 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK41664.1 - 1.7e-06 28.1 0.0 3.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK41664.1 - 2e-06 27.4 0.2 5.4e-06 26.1 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK41664.1 - 0.00033 20.6 0.1 0.00054 19.9 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KIK41664.1 - 0.0072 15.8 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KIK41664.1 - 0.1 12.9 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain ING PF12998.7 KIK41665.1 - 9e-14 51.9 0.2 1.5e-13 51.2 0.2 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KIK41665.1 - 5.6e-06 26.2 5.8 9e-06 25.5 5.8 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KIK41665.1 - 0.065 12.8 1.0 0.12 12.0 1.0 1.4 1 0 0 1 1 1 0 PHD-finger FAM27 PF15832.5 KIK41665.1 - 0.18 12.4 5.8 0.52 10.9 3.4 2.3 2 0 0 2 2 2 0 FAM27 D and E protein family Ca_hom_mod PF14798.6 KIK41667.1 - 0.067 12.3 0.1 0.07 12.2 0.1 1.1 1 0 0 1 1 1 0 Calcium homeostasis modulator zf-4CXXC_R1 PF10497.9 KIK41670.1 - 0.18 12.1 0.1 0.34 11.2 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 CBM_5_12 PF02839.14 KIK41672.1 - 0.0056 17.2 18.4 0.13 12.9 3.7 2.9 2 0 0 2 2 2 2 Carbohydrate binding domain Tmp39 PF10271.9 KIK41672.1 - 0.86 8.5 2.9 0.77 8.7 0.5 1.8 1 1 1 2 2 2 0 Putative transmembrane protein DUF1772 PF08592.11 KIK41674.1 - 0.85 9.9 10.0 1.7 9.0 9.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) MFS_1 PF07690.16 KIK41676.1 - 7.3e-15 54.7 17.6 9.8e-15 54.3 17.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1378 PF07125.11 KIK41676.1 - 0.32 11.2 1.2 0.75 10.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1378) Hira PF07569.11 KIK41677.1 - 1.8e-50 171.8 0.3 5.2e-50 170.2 0.1 2.0 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 KIK41677.1 - 8.2e-29 99.3 17.1 1.3e-05 25.8 0.4 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41677.1 - 3.9e-13 49.5 0.8 0.095 13.0 0.0 6.5 3 1 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.8 KIK41677.1 - 0.013 14.9 0.1 0.033 13.6 0.1 1.6 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region DUF4336 PF14234.6 KIK41678.1 - 1.2e-14 54.3 0.0 4.9e-09 35.8 0.0 2.8 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) zf-C2H2_4 PF13894.6 KIK41680.1 - 2.1e-25 87.2 110.6 0.014 16.2 0.1 20.7 20 1 1 21 21 21 11 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK41680.1 - 5.2e-21 73.9 111.0 0.00085 19.7 0.1 19.3 20 1 1 21 21 19 11 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KIK41680.1 - 1.5e-09 37.9 79.0 0.0025 18.0 2.1 15.2 17 1 1 18 18 16 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIK41680.1 - 1.3e-08 34.9 84.7 8.9e-05 22.7 2.8 16.1 18 0 0 18 18 17 6 Zinc-finger of C2H2 type zf-C3HC4 PF00097.25 KIK41680.1 - 2.9e-06 27.0 11.8 2.9e-06 27.0 11.8 7.6 9 1 0 9 9 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK41680.1 - 3.4e-06 26.9 13.2 3.4e-06 26.9 13.2 8.5 8 2 0 8 8 6 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KIK41680.1 - 2.5e-05 24.0 12.0 2.5e-05 24.0 12.0 7.8 9 1 0 9 9 5 1 Zinc finger, C3HC4 type (RING finger) zf_ZIC PF18366.1 KIK41680.1 - 5e-05 23.3 11.0 0.28 11.3 0.5 5.5 4 1 1 5 5 5 2 Zic proteins zinc finger domain zf-C3HC4_3 PF13920.6 KIK41680.1 - 6.2e-05 22.8 10.9 6.2e-05 22.8 10.9 8.4 11 1 0 11 11 10 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK41680.1 - 8.9e-05 22.7 13.3 8.9e-05 22.7 13.3 8.5 10 1 2 12 12 7 1 Ring finger domain zf-C2H2_11 PF16622.5 KIK41680.1 - 0.0012 18.5 2.6 0.019 14.7 0.6 10.9 10 2 2 12 12 12 3 zinc-finger C2H2-type zf-RING_UBOX PF13445.6 KIK41680.1 - 0.0015 18.5 4.7 0.0015 18.5 4.7 5.9 4 2 1 5 5 5 1 RING-type zinc-finger zf-C2H2_2 PF12756.7 KIK41680.1 - 0.015 15.6 4.8 0.015 15.6 4.8 10.8 4 2 8 13 13 11 0 C2H2 type zinc-finger (2 copies) zf_Hakai PF18408.1 KIK41680.1 - 0.065 13.0 18.3 3.7 7.3 1.1 6.5 6 0 0 6 6 6 0 C2H2 Hakai zinc finger domain ARS2 PF04959.13 KIK41680.1 - 0.13 12.6 1.0 6.8 7.0 0.1 2.9 2 0 0 2 2 2 0 Arsenite-resistance protein 2 zf-H2C2_2 PF13465.6 KIK41680.1 - 0.23 11.9 72.3 0.38 11.3 1.5 14.7 15 1 0 15 15 14 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KIK41681.1 - 3.5e-06 27.2 26.6 0.00014 22.1 0.2 6.5 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIK41681.1 - 4.4e-06 26.9 0.2 4.4e-06 26.9 0.2 5.2 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KIK41681.1 - 5.5e-06 26.8 40.3 0.06 14.2 0.4 7.1 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KIK41681.1 - 0.015 15.3 1.7 0.015 15.3 1.7 5.6 5 1 1 6 6 6 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KIK41681.1 - 0.043 13.7 0.1 0.043 13.7 0.1 6.3 7 0 0 7 7 7 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 KIK41681.1 - 0.05 14.1 1.3 0.05 14.1 1.3 5.7 6 0 0 6 6 6 0 Zinc-finger double domain zf-C2H2 PF00096.26 KIK41681.1 - 0.14 12.6 41.0 1.1 9.8 0.5 6.8 7 0 0 7 7 7 0 Zinc finger, C2H2 type zf-RING_2 PF13639.6 KIK41682.1 - 3.8e-06 27.1 10.7 1.1e-05 25.7 10.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK41682.1 - 4.1e-06 26.5 10.6 4.1e-06 26.5 10.6 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK41682.1 - 6.6e-06 25.9 10.6 6.6e-06 25.9 10.6 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK41682.1 - 6.7e-06 25.9 10.0 1.4e-05 24.8 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK41682.1 - 6.9e-06 25.9 9.8 6.9e-06 25.9 9.8 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIK41682.1 - 0.001 19.0 3.5 0.001 19.0 3.5 2.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.7 KIK41682.1 - 0.0067 16.7 6.2 0.018 15.4 6.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KIK41682.1 - 0.0083 16.0 8.7 0.017 15.0 8.7 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KIK41682.1 - 0.013 15.4 10.6 0.013 15.4 10.6 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KIK41682.1 - 0.16 12.2 12.1 0.22 11.7 10.1 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KIK41682.1 - 0.23 11.3 5.2 0.51 10.2 5.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KIK41682.1 - 0.39 10.9 9.6 1.2 9.4 9.6 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Period_C PF12114.8 KIK41682.1 - 2.2 7.8 7.6 0.34 10.5 3.4 1.6 1 1 0 2 2 2 0 Period protein 2/3C-terminal region SNURF PF07192.11 KIK41683.1 - 0.13 12.1 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 SNURF/RPN4 protein FTR1 PF03239.14 KIK41684.1 - 5.1e-62 209.8 9.0 6e-62 209.6 9.0 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3341 PF11821.8 KIK41684.1 - 5.9 6.5 6.4 17 5.0 0.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3341) Cu-oxidase PF00394.22 KIK41685.1 - 2.7e-38 131.6 0.2 1.1e-34 119.9 0.0 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK41685.1 - 3.2e-38 130.6 2.5 2.5e-35 121.2 0.1 3.3 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK41685.1 - 3.1e-33 114.3 5.4 2.7e-30 104.8 0.3 4.8 5 1 0 5 5 5 2 Multicopper oxidase DUF2802 PF10975.8 KIK41686.1 - 0.15 12.2 1.9 7.5 6.8 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) CBM_1 PF00734.18 KIK41687.1 - 0.11 12.4 0.4 0.11 12.4 0.4 2.2 2 0 0 2 2 2 0 Fungal cellulose binding domain CBM_19 PF03427.13 KIK41687.1 - 2 8.4 12.8 0.3 11.1 7.8 2.1 1 1 2 3 3 3 0 Carbohydrate binding domain (family 19) SHMT PF00464.19 KIK41688.1 - 1.3e-169 564.0 0.0 1.5e-169 563.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 KIK41688.1 - 0.083 12.1 0.0 0.16 11.2 0.0 1.5 2 0 0 2 2 2 0 Beta-eliminating lyase COesterase PF00135.28 KIK41692.1 - 1.1e-60 206.0 0.0 5.3e-53 180.7 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_6 PF12697.7 KIK41692.1 - 0.00011 22.9 0.6 0.00025 21.7 0.6 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KIK41692.1 - 0.037 13.9 0.2 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF1749 PF08538.10 KIK41692.1 - 0.085 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Syndecan PF01034.20 KIK41693.1 - 1.8 8.5 4.8 6.3 6.8 0.3 2.7 2 0 0 2 2 2 0 Syndecan domain NACHT PF05729.12 KIK41694.1 - 1.7e-07 31.3 0.8 4.9e-07 29.8 0.8 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK41694.1 - 5.5e-05 23.6 0.2 7.2e-05 23.2 0.2 1.2 1 0 0 1 1 1 1 AAA ATPase domain Glyco_hydro_18 PF00704.28 KIK41695.1 - 5.4e-55 187.3 3.6 6.5e-55 187.0 3.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_114 PF03537.13 KIK41695.1 - 0.082 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 JTB PF05439.12 KIK41697.1 - 3.1e-05 24.0 0.2 7.8e-05 22.7 0.2 1.6 1 1 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) SRP19 PF01922.17 KIK41698.1 - 1.5e-26 93.2 0.0 2.3e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein BTB PF00651.31 KIK41699.1 - 0.00042 20.5 0.0 0.00071 19.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BCNT PF07572.12 KIK41700.1 - 1.6e-21 76.1 0.5 1.6e-21 76.1 0.5 1.7 2 0 0 2 2 2 1 Bucentaur or craniofacial development zf-MYND PF01753.18 KIK41701.1 - 8.3 6.6 7.0 2.9 8.1 3.8 2.0 2 0 0 2 2 2 0 MYND finger SAD_SRA PF02182.17 KIK41704.1 - 5.4e-52 175.6 0.2 5.4e-52 175.6 0.2 1.9 2 0 0 2 2 2 1 SAD/SRA domain IMS PF00817.20 KIK41705.1 - 9.5e-43 145.8 0.0 1.8e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KIK41705.1 - 9.8e-18 65.0 0.0 2.3e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 KIK41705.1 - 1.2e-05 24.8 0.9 0.0023 17.5 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 KIK41705.1 - 0.0032 17.7 0.0 0.0081 16.4 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif CIA30 PF08547.12 KIK41707.1 - 4.6e-26 91.7 0.0 5.6e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 KIK41707.1 - 0.048 13.6 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Surface glycan-binding protein B xyloglucan binding domain Ras PF00071.22 KIK41708.1 - 1.6e-58 196.8 0.2 1.9e-58 196.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK41708.1 - 1.9e-20 73.3 0.0 3.3e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK41708.1 - 6.3e-09 35.5 0.0 7.6e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIK41708.1 - 7e-06 25.7 0.1 1.4e-05 24.7 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIK41708.1 - 5.6e-05 23.1 0.4 0.095 12.6 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KIK41708.1 - 0.0015 18.6 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIK41708.1 - 0.0046 16.5 0.1 0.014 14.9 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Ser_hydrolase PF06821.13 KIK41708.1 - 0.078 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase ATP_bind_1 PF03029.17 KIK41708.1 - 0.1 12.4 2.5 0.57 9.9 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein P3A PF08727.11 KIK41710.1 - 0.033 13.6 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Poliovirus 3A protein like Aldedh PF00171.22 KIK41711.1 - 1.9e-174 580.5 0.0 2.1e-174 580.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PRiA4_ORF3 PF07929.11 KIK41712.1 - 9.4e-30 103.6 0.0 4.2e-29 101.5 0.0 1.8 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein SH3_1 PF00018.28 KIK41713.1 - 2.3e-14 52.7 0.5 3.3e-14 52.2 0.5 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KIK41713.1 - 7.8e-13 47.9 0.0 1.3e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KIK41713.1 - 2.7e-11 43.1 0.1 4.4e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain PRiA4_ORF3 PF07929.11 KIK41714.1 - 2.2e-35 121.9 0.0 7.3e-35 120.2 0.0 1.7 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein YqhG PF11079.8 KIK41714.1 - 0.2 10.6 0.1 0.29 10.1 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function RNase_H PF00075.24 KIK41715.1 - 8.2e-19 68.2 0.0 1.2e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KIK41715.1 - 0.0058 16.4 0.1 0.21 11.4 0.1 2.1 1 1 0 1 1 1 1 Reverse transcriptase-like DSBA PF01323.20 KIK41716.1 - 6.8e-27 94.5 0.1 1.1e-26 93.8 0.1 1.3 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KIK41716.1 - 2.4e-06 27.8 0.3 5.4e-06 26.7 0.0 1.7 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 KIK41716.1 - 0.022 14.8 2.2 0.053 13.6 0.8 2.4 2 1 0 2 2 2 0 Thioredoxin domain Thioredoxin_5 PF13743.6 KIK41716.1 - 0.027 14.2 0.4 0.39 10.4 0.1 2.0 1 1 0 2 2 2 0 Thioredoxin MafB19-deam PF14437.6 KIK41716.1 - 0.051 13.3 0.4 1 9.1 0.1 2.1 2 0 0 2 2 2 0 MafB19-like deaminase His_biosynth PF00977.21 KIK41717.1 - 0.024 14.1 0.0 0.032 13.7 0.0 1.1 1 0 0 1 1 1 0 Histidine biosynthesis protein Fungal_KA1 PF16797.5 KIK41717.1 - 0.082 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Fungal kinase associated-1 domain SIR2 PF02146.17 KIK41718.1 - 4.5e-30 104.9 0.0 8.4e-20 71.4 0.0 2.5 2 1 0 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 KIK41718.1 - 0.078 12.7 0.3 1.2 8.9 0.1 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain KAR9 PF08580.10 KIK41718.1 - 2.3 6.7 7.1 0.66 8.4 3.9 1.6 2 0 0 2 2 2 0 Yeast cortical protein KAR9 ADH_zinc_N PF00107.26 KIK41719.1 - 2.1e-12 47.2 0.0 3.5e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK41719.1 - 1.4e-09 37.8 0.1 3.1e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIK41719.1 - 0.025 15.6 0.0 0.045 14.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIK41719.1 - 0.07 13.0 0.0 0.2 11.6 0.0 1.7 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KIK41720.1 - 2.5e-12 46.9 0.0 4.6e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK41720.1 - 5.9e-10 39.0 0.0 9.2e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KIK41720.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase DSS1_SEM1 PF05160.13 KIK41721.1 - 1.2e-23 82.9 8.3 1.2e-23 82.9 8.3 1.4 1 1 0 1 1 1 1 DSS1/SEM1 family Sugar_tr PF00083.24 KIK41723.1 - 3.9e-34 118.3 30.9 7.3e-22 77.8 7.8 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KIK41723.1 - 7.5e-20 71.2 62.1 1.5e-18 66.9 36.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NTF2 PF02136.20 KIK41724.1 - 0.13 12.8 0.1 0.35 11.4 0.1 1.7 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Pkinase PF00069.25 KIK41725.1 - 3.3e-21 75.8 0.0 1.2e-14 54.4 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK41725.1 - 1.2e-09 37.9 0.0 3e-05 23.4 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK41725.1 - 5.5e-08 32.0 0.0 7.7e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK41725.1 - 0.073 13.0 0.0 0.57 10.1 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family p450 PF00067.22 KIK41727.1 - 1.1e-58 199.2 0.0 1.4e-58 198.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phage_base_V PF04717.12 KIK41727.1 - 0.03 14.2 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion system, phage-baseplate injector Acetate_kinase PF00871.17 KIK41728.1 - 1.1e-88 297.5 0.0 1.5e-88 297.2 0.0 1.1 1 0 0 1 1 1 1 Acetokinase family Dynamin_N PF00350.23 KIK41729.1 - 0.002 18.2 3.1 0.022 14.8 0.0 2.3 2 1 0 2 2 2 1 Dynamin family AIG1 PF04548.16 KIK41729.1 - 0.029 13.7 0.2 0.049 13.0 0.1 1.7 1 1 0 1 1 1 0 AIG1 family YtxH PF12732.7 KIK41729.1 - 0.057 14.0 3.4 0.13 12.9 3.4 1.5 1 0 0 1 1 1 0 YtxH-like protein Mitofilin PF09731.9 KIK41729.1 - 0.088 11.6 12.5 0.11 11.3 12.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein HAUS6_N PF14661.6 KIK41729.1 - 1.1 8.8 7.2 1.4 8.5 7.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus OmpH PF03938.14 KIK41729.1 - 3 8.2 10.4 1.5 9.2 8.3 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 KIK41729.1 - 9.2 5.4 7.7 13 4.9 7.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein MMR_HSR1 PF01926.23 KIK41731.1 - 2.8e-06 27.4 0.1 2.8e-06 27.4 0.1 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KIK41731.1 - 4e-05 23.7 10.4 0.00027 21.0 0.2 3.2 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 KIK41731.1 - 9.2e-05 21.9 0.4 9.2e-05 21.9 0.4 2.3 1 1 1 2 2 2 1 AIG1 family Septin PF00735.18 KIK41731.1 - 0.00051 19.4 0.1 0.00051 19.4 0.1 2.2 2 1 0 2 2 2 1 Septin RsgA_GTPase PF03193.16 KIK41731.1 - 0.0029 17.5 0.3 0.0029 17.5 0.3 2.4 2 1 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 KIK41731.1 - 0.01 15.3 0.1 0.01 15.3 0.1 1.9 3 0 0 3 3 3 0 Ferrous iron transport protein B Strep_SA_rep PF06696.11 KIK41731.1 - 0.068 13.2 3.0 5.2 7.2 0.1 3.4 3 0 0 3 3 3 0 Streptococcal surface antigen repeat AAA_23 PF13476.6 KIK41731.1 - 0.21 12.1 12.9 1.2 9.6 6.3 2.4 2 0 0 2 2 2 0 AAA domain UPF0242 PF06785.11 KIK41731.1 - 0.4 10.8 10.4 0.72 9.9 10.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FapA PF03961.13 KIK41731.1 - 1.2 7.7 5.5 1.6 7.3 5.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1682 PF07946.14 KIK41731.1 - 1.7 7.8 9.1 2.3 7.3 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) AAA_11 PF13086.6 KIK41731.1 - 2 8.1 8.4 1.9 8.2 7.0 1.6 2 0 0 2 2 2 0 AAA domain OmpH PF03938.14 KIK41731.1 - 2.1 8.7 19.9 5 7.5 19.9 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_22 PF13401.6 KIK41731.1 - 2.5 8.4 6.4 13 6.0 1.3 2.7 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KIK41731.1 - 9.5 5.9 7.5 7.7 6.2 0.6 2.9 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein FA_hydroxylase PF04116.13 KIK41732.1 - 8.8e-23 81.1 20.8 8.8e-23 81.1 20.8 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily WD40 PF00400.32 KIK41734.1 - 3.6e-20 71.9 8.0 0.00069 20.4 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41734.1 - 3.6e-11 43.2 0.1 0.0056 16.9 0.1 5.3 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK41734.1 - 0.00015 21.7 0.1 0.029 14.3 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KIK41734.1 - 0.0015 16.9 0.0 1.2 7.3 0.0 2.7 1 1 2 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK41734.1 - 0.01 15.2 0.0 0.16 11.2 0.0 2.5 3 0 0 3 3 3 0 WD40-like domain Ge1_WD40 PF16529.5 KIK41734.1 - 0.027 13.4 0.0 5.5 5.9 0.0 3.0 2 2 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein LEM PF03020.15 KIK41734.1 - 0.037 13.6 0.0 0.078 12.6 0.0 1.5 1 0 0 1 1 1 0 LEM domain XFP_N PF09364.10 KIK41735.1 - 1.7e-146 487.7 0.0 2.2e-146 487.4 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 KIK41735.1 - 4.6e-78 260.9 0.0 8.6e-78 260.1 0.0 1.5 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 KIK41735.1 - 2.7e-76 255.5 0.0 3.8e-76 255.0 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.21 KIK41735.1 - 0.0029 17.4 0.1 0.0065 16.3 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain MMR_HSR1 PF01926.23 KIK41737.1 - 8e-08 32.4 2.1 2.7e-07 30.6 0.0 2.6 2 2 1 3 3 3 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK41737.1 - 3.7e-05 23.2 2.8 3.9e-05 23.1 0.0 2.0 1 1 1 2 2 2 1 AIG1 family Dynamin_N PF00350.23 KIK41737.1 - 0.00016 21.8 10.5 0.0013 18.8 0.0 3.4 2 2 1 3 3 3 2 Dynamin family FeoB_N PF02421.18 KIK41737.1 - 0.00043 19.8 0.0 0.0095 15.5 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KIK41737.1 - 0.0015 18.5 0.1 0.0015 18.5 0.1 2.6 2 1 1 3 3 3 1 RsgA GTPase Septin PF00735.18 KIK41737.1 - 0.0036 16.6 0.0 0.0036 16.6 0.0 2.9 2 2 1 3 3 3 1 Septin SRPRB PF09439.10 KIK41737.1 - 0.026 14.0 0.0 0.026 14.0 0.0 2.7 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 KIK41737.1 - 0.036 13.8 1.1 0.061 13.0 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KIK41737.1 - 0.11 12.3 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Fib_alpha PF08702.10 KIK41737.1 - 0.11 12.7 6.0 0.22 11.7 6.0 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 KIK41737.1 - 0.15 12.1 16.4 0.22 11.6 16.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ATP_bind_1 PF03029.17 KIK41737.1 - 0.3 10.8 0.2 0.3 10.8 0.2 2.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 KIK41737.1 - 0.34 11.4 0.1 0.34 11.4 0.1 2.8 2 1 0 2 2 2 0 ABC transporter AAA_17 PF13207.6 KIK41737.1 - 0.67 10.4 7.2 10 6.6 3.6 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KIK41737.1 - 0.93 10.0 16.0 1.4 9.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain DUF4094 PF13334.6 KIK41737.1 - 5.5 7.5 7.9 9.6 6.7 5.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4094) TPR_10 PF13374.6 KIK41738.1 - 8.5e-24 82.7 18.8 0.0015 18.3 0.0 14.4 14 2 0 14 14 14 8 Tetratricopeptide repeat TPR_12 PF13424.6 KIK41738.1 - 4.8e-15 55.6 17.1 8.4 6.8 0.0 13.0 14 0 0 14 14 14 5 Tetratricopeptide repeat KH_7 PF17214.3 KIK41738.1 - 2.6e-07 30.5 0.0 21 5.2 0.0 8.0 10 0 0 10 10 10 0 KH domain Imm53 PF15580.6 KIK41738.1 - 4.4e-06 26.3 0.0 13 5.6 0.0 8.2 12 0 0 12 12 12 1 Immunity protein 53 TPR_2 PF07719.17 KIK41738.1 - 2e-05 24.3 4.2 32 5.0 0.0 7.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK41738.1 - 0.0041 17.8 22.9 37 5.5 0.1 10.8 14 0 0 14 14 14 0 Tetratricopeptide repeat IcmF-related PF06761.12 KIK41738.1 - 0.03 13.8 0.0 57 3.0 0.0 4.1 1 1 4 5 5 5 0 Intracellular multiplication and human macrophage-killing TPR_1 PF00515.28 KIK41738.1 - 0.14 12.0 19.2 47 4.0 0.0 10.9 16 0 0 16 16 16 0 Tetratricopeptide repeat DnaB_bind PF10410.9 KIK41738.1 - 6 7.1 14.5 2.3e+02 2.1 0.1 7.4 9 0 0 9 9 9 0 DnaB-helicase binding domain of primase Thioredoxin PF00085.20 KIK41739.1 - 1.2e-54 182.6 0.0 3.2e-26 91.3 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 KIK41739.1 - 3.8e-25 88.6 0.9 7.4e-25 87.7 0.9 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 KIK41739.1 - 1.8e-15 57.3 0.1 1.7e-08 34.9 0.1 2.6 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KIK41739.1 - 2e-11 43.8 0.0 7.1e-05 22.3 0.0 2.3 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KIK41739.1 - 1.4e-08 34.7 0.0 0.0014 18.6 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 KIK41739.1 - 5.4e-08 32.9 0.0 0.0013 18.9 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KIK41739.1 - 1.1e-07 32.0 0.0 0.17 12.3 0.0 3.7 2 2 1 3 3 3 2 Thioredoxin-like Thioredoxin_6 PF13848.6 KIK41739.1 - 3.4e-05 23.9 0.0 1.2 9.0 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like domain Redoxin PF08534.10 KIK41739.1 - 0.00014 21.6 0.1 0.28 10.9 0.0 2.6 2 1 0 2 2 2 2 Redoxin Glutaredoxin PF00462.24 KIK41739.1 - 0.00019 21.6 0.1 0.032 14.4 0.0 2.8 2 0 0 2 2 2 1 Glutaredoxin TraF PF13728.6 KIK41739.1 - 0.00036 20.4 0.0 0.73 9.6 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein HyaE PF07449.11 KIK41739.1 - 0.018 15.0 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KIK41739.1 - 0.042 13.6 0.7 1.8 8.3 0.0 2.6 3 0 0 3 3 3 0 Thioredoxin LUC7 PF03194.15 KIK41739.1 - 0.043 13.5 0.7 0.066 12.9 0.7 1.2 1 0 0 1 1 1 0 LUC7 N_terminus Thioredoxin_4 PF13462.6 KIK41739.1 - 0.14 12.3 2.5 35 4.5 0.1 3.7 3 1 1 4 4 4 0 Thioredoxin WD40 PF00400.32 KIK41740.1 - 1.5e-33 114.3 20.5 9.5e-09 35.8 0.1 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41740.1 - 3.7e-12 46.4 0.1 0.0068 16.7 0.0 5.5 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK41740.1 - 9.2e-07 28.1 0.0 0.004 16.2 0.0 2.7 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK41740.1 - 5.8e-05 22.6 0.0 4.1 6.6 0.0 3.9 4 0 0 4 4 4 2 WD40-like domain PQQ_2 PF13360.6 KIK41740.1 - 0.0001 22.0 4.0 0.0007 19.2 1.1 3.0 1 1 2 3 3 3 2 PQQ-like domain Glyoxal_oxid_N PF07250.11 KIK41740.1 - 0.025 13.8 0.1 0.054 12.7 0.1 1.5 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus Nup160 PF11715.8 KIK41740.1 - 0.072 11.7 0.9 0.72 8.4 0.1 2.5 2 1 1 3 3 3 0 Nucleoporin Nup120/160 WDCP PF15390.6 KIK41740.1 - 0.15 10.4 0.0 0.21 9.9 0.0 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family PQQ_3 PF13570.6 KIK41740.1 - 0.54 10.8 10.6 7.3 7.2 0.0 5.4 6 0 0 6 6 6 0 PQQ-like domain DUF1479 PF07350.12 KIK41742.1 - 6.1e-128 427.1 0.0 7e-128 426.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Mad3_BUB1_I PF08311.12 KIK41744.1 - 1.4e-36 125.2 1.8 2.2e-36 124.5 1.8 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 KIK41744.1 - 1.7e-11 44.0 0.0 1.7e-10 40.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Mad3_BUB1_II PF08171.11 KIK41744.1 - 4.2e-06 26.8 0.0 1.4e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.17 KIK41744.1 - 5.5e-06 25.9 0.0 8.6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 KIK41744.1 - 0.0066 16.6 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein LsmAD PF06741.13 KIK41745.1 - 5.8e-28 97.2 1.2 1.2e-27 96.3 1.2 1.5 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 KIK41745.1 - 2.4e-06 27.6 0.0 4.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KIK41745.1 - 0.046 13.8 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Scd6-like Sm domain Sun2_CC2 PF18580.1 KIK41745.1 - 0.65 10.3 2.6 1 9.6 0.1 2.3 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 SVA PF05326.11 KIK41747.1 - 0.022 14.8 0.4 0.034 14.1 0.4 1.4 1 0 0 1 1 1 0 Seminal vesicle autoantigen (SVA) MIP PF00230.20 KIK41748.1 - 1.4e-27 96.9 11.2 1.9e-27 96.4 11.2 1.2 1 0 0 1 1 1 1 Major intrinsic protein ADH_N_2 PF16884.5 KIK41750.1 - 1.5e-28 98.8 0.1 3.6e-28 97.6 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KIK41750.1 - 1.7e-17 63.6 0.0 2.8e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK41750.1 - 7.3e-08 33.5 0.0 1.3e-07 32.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RhoGEF PF00621.20 KIK41755.1 - 3.8e-33 115.2 1.4 5.7e-33 114.7 1.4 1.3 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.22 KIK41755.1 - 8.7e-32 110.8 0.0 1.6e-31 109.9 0.0 1.4 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 KIK41755.1 - 4.4e-08 33.3 0.0 1e-07 32.1 0.0 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KIK41755.1 - 0.013 16.0 0.0 0.034 14.6 0.0 1.8 1 1 0 1 1 1 0 PH domain DUF883 PF05957.13 KIK41757.1 - 2 9.1 5.0 7.6 7.2 2.2 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Xpo1 PF08389.12 KIK41759.1 - 3.2e-15 56.5 0.0 3.2e-15 56.5 0.0 4.7 6 2 2 8 8 8 1 Exportin 1-like protein HEAT_2 PF13646.6 KIK41759.1 - 0.0046 17.3 0.2 0.33 11.4 0.0 3.6 3 0 0 3 3 3 1 HEAT repeats ERAP1_C PF11838.8 KIK41759.1 - 0.014 15.0 1.3 0.12 11.9 0.1 2.9 4 0 0 4 4 4 0 ERAP1-like C-terminal domain 7TMR-HDED PF07697.11 KIK41759.1 - 0.058 13.5 2.4 0.31 11.2 0.3 3.0 2 1 0 2 2 2 0 7TM-HD extracellular EBV-NA3 PF05009.12 KIK41759.1 - 0.11 12.0 0.0 0.37 10.3 0.0 1.8 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Urb2 PF10441.9 KIK41759.1 - 0.13 12.2 0.8 9.5 6.1 0.0 3.7 3 1 1 4 4 4 0 Urb2/Npa2 family Cullin PF00888.22 KIK41760.1 - 3.3e-207 689.9 0.0 4.2e-207 689.6 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KIK41760.1 - 2.4e-29 101.1 3.0 4.4e-29 100.3 1.5 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain SecA_SW PF07516.13 KIK41760.1 - 0.0063 16.6 1.5 0.41 10.7 0.0 2.6 2 0 0 2 2 2 1 SecA Wing and Scaffold domain Poxvirus_B22R_N PF13169.6 KIK41760.1 - 0.02 15.3 0.5 8.3 7.0 0.1 2.6 2 0 0 2 2 2 0 Poxvirus B22R protein N-terminal Penicillinase_R PF03965.16 KIK41760.1 - 0.067 13.5 0.0 0.24 11.8 0.0 2.0 1 0 0 1 1 1 0 Penicillinase repressor tRNA_synthFbeta PF17759.1 KIK41761.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain DnaJ PF00226.31 KIK41762.1 - 3.9e-25 87.8 3.0 5.8e-25 87.2 3.0 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 KIK41762.1 - 2e-23 83.1 0.0 8.4e-23 81.1 0.0 1.9 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KIK41762.1 - 2.9e-14 53.2 17.6 5.2e-14 52.4 17.6 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KIK41762.1 - 0.00026 21.0 3.8 0.1 12.6 1.1 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KIK41762.1 - 0.0006 19.7 10.7 0.0044 17.0 1.2 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Lar_restr_allev PF14354.6 KIK41762.1 - 0.033 14.6 10.1 0.11 12.9 0.3 3.1 2 1 1 3 3 3 0 Restriction alleviation protein Lar NRDD PF13597.6 KIK41762.1 - 1.2 7.8 9.2 0.034 12.9 2.0 1.9 1 1 1 2 2 2 0 Anaerobic ribonucleoside-triphosphate reductase TackOD1 PF18551.1 KIK41762.1 - 1.3 8.7 6.1 0.31 10.7 0.7 2.1 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zinc_ribbon_6 PF14599.6 KIK41762.1 - 5.6 7.1 5.5 4.6 7.3 0.7 2.5 2 0 0 2 2 2 0 Zinc-ribbon Ilar_coat PF01787.16 KIK41763.1 - 0.032 14.0 0.3 0.47 10.2 0.2 2.1 1 1 1 2 2 2 0 Ilarvirus coat protein F-box-like PF12937.7 KIK41764.1 - 0.0003 20.6 4.9 0.0009 19.1 0.3 3.8 4 0 0 4 4 4 1 F-box-like F-box PF00646.33 KIK41764.1 - 0.04 13.8 3.8 2.6 8.0 0.1 4.0 4 0 0 4 4 4 0 F-box domain WLM PF08325.10 KIK41765.1 - 4.7e-31 108.4 5.4 4.7e-31 108.4 5.4 2.3 2 1 0 2 2 2 1 WLM domain zf-RanBP PF00641.18 KIK41765.1 - 5.3e-07 28.8 2.3 9.6e-07 28.0 2.3 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF45 PF01863.17 KIK41765.1 - 5.6e-06 26.5 0.7 1.5e-05 25.1 0.6 1.7 1 1 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.9 KIK41765.1 - 0.038 13.9 0.1 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 SprT-like family Asp PF00026.23 KIK41766.1 - 2.9e-46 158.4 0.5 3.8e-46 157.9 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK41766.1 - 8e-11 42.5 5.0 1.1e-09 38.8 3.3 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK41766.1 - 0.052 14.2 1.3 0.77 10.4 0.3 3.1 2 1 0 2 2 2 0 Aspartyl protease RasGAP PF00616.19 KIK41767.1 - 1.2e-58 198.3 0.3 7.6e-58 195.6 0.0 2.4 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KIK41767.1 - 2e-37 128.4 0.3 5.8e-37 126.9 0.3 1.9 1 0 0 1 1 1 1 RasGAP C-terminus zf-C2H2_2 PF12756.7 KIK41770.1 - 0.054 13.8 0.9 0.23 11.8 0.9 1.9 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) BRO1 PF03097.18 KIK41772.1 - 5e-104 348.2 0.0 7.5e-104 347.6 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KIK41772.1 - 1.6e-75 254.2 6.5 1.6e-75 254.2 6.5 1.5 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV GARP PF16731.5 KIK41774.1 - 0.025 14.3 0.7 0.025 14.3 0.7 1.5 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma zf-RING_2 PF13639.6 KIK41778.1 - 1.9e-09 37.7 11.6 2.9e-09 37.1 11.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK41778.1 - 5.6e-09 35.7 10.8 8.6e-09 35.1 10.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK41778.1 - 3e-08 33.4 6.7 4.3e-08 32.9 6.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK41778.1 - 5.4e-08 32.6 10.0 8.2e-08 32.0 10.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIK41778.1 - 1.3e-06 28.6 10.2 3.3e-06 27.3 10.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KIK41778.1 - 1.4e-05 25.0 6.7 2.7e-05 24.1 6.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIK41778.1 - 4.6e-05 23.3 9.5 6.8e-05 22.7 9.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIK41778.1 - 6.6e-05 22.7 7.8 0.00011 22.0 7.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KIK41778.1 - 0.0014 18.7 11.0 0.0086 16.2 11.4 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KIK41778.1 - 0.032 14.0 9.5 0.065 13.0 9.5 1.6 1 0 0 1 1 1 0 RING-like zinc finger Siva PF05458.12 KIK41778.1 - 0.044 13.5 1.7 0.065 12.9 1.7 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-RING_10 PF16685.5 KIK41778.1 - 0.078 13.1 2.9 0.13 12.4 2.9 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 KIK41778.1 - 0.094 12.8 5.7 0.27 11.3 5.4 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KIK41778.1 - 0.16 11.7 7.6 0.48 10.3 7.6 1.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 KIK41778.1 - 0.2 11.3 7.6 0.53 10.0 7.6 1.7 1 1 0 1 1 1 0 P-11 zinc finger DUF2946 PF11162.8 KIK41778.1 - 2.8 8.6 9.1 5 7.8 0.8 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2946) Homeodomain PF00046.29 KIK41779.1 - 3.6e-11 42.7 0.3 1e-10 41.3 0.3 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KIK41779.1 - 0.028 14.3 0.6 0.23 11.4 0.1 2.7 2 0 0 2 2 2 0 Homeobox KN domain UT PF03253.14 KIK41781.1 - 0.035 13.2 0.1 0.044 12.9 0.1 1.1 1 0 0 1 1 1 0 Urea transporter Tannase PF07519.11 KIK41782.1 - 0.028 13.3 0.1 0.22 10.4 0.0 2.0 2 0 0 2 2 2 0 Tannase and feruloyl esterase Bromodomain PF00439.25 KIK41782.1 - 0.056 13.5 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Bromodomain TPR_10 PF13374.6 KIK41783.1 - 9.4e-49 162.0 27.6 1.2e-05 25.0 0.1 18.1 18 1 0 18 18 18 9 Tetratricopeptide repeat CHAT PF12770.7 KIK41783.1 - 1.9e-35 122.7 0.1 5.6e-35 121.2 0.1 1.8 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 KIK41783.1 - 3.1e-21 75.4 23.7 0.16 12.3 0.4 15.2 12 4 5 17 17 17 5 Tetratricopeptide repeat TPR_7 PF13176.6 KIK41783.1 - 2e-12 46.2 5.1 7.9 6.8 0.0 13.3 14 1 0 14 14 13 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK41783.1 - 1.3e-06 28.0 17.0 31 4.6 0.0 14.0 17 0 0 17 17 16 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK41783.1 - 0.00014 21.8 0.0 88 3.7 0.0 7.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK41783.1 - 0.0036 17.9 17.2 0.48 11.1 0.1 8.6 5 2 6 11 11 11 2 Tetratricopeptide repeat AKAP7_NLS PF10469.9 KIK41783.1 - 0.0056 16.6 2.5 32 4.3 0.0 6.1 8 1 1 9 9 9 0 AKAP7 2'5' RNA ligase-like domain YkuI_C PF10388.9 KIK41783.1 - 0.011 15.6 0.0 3.8 7.3 0.0 5.1 6 1 0 6 6 6 0 EAL-domain associated signalling protein domain TPR_11 PF13414.6 KIK41783.1 - 0.02 14.6 2.3 35 4.2 0.0 7.0 10 0 0 10 10 10 0 TPR repeat TPR_14 PF13428.6 KIK41783.1 - 0.023 15.5 19.1 36 5.5 0.0 10.9 14 0 0 14 14 9 0 Tetratricopeptide repeat Surp PF01805.20 KIK41783.1 - 0.034 14.2 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 Surp module TrwB_AAD_bind PF10412.9 KIK41783.1 - 0.046 12.6 0.1 0.093 11.6 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain SNURF PF07192.11 KIK41783.1 - 0.078 12.8 1.7 2.8 7.8 0.0 4.0 5 0 0 5 5 4 0 SNURF/RPN4 protein EccE PF11203.8 KIK41783.1 - 0.084 13.2 1.8 11 6.4 0.0 4.9 3 1 2 5 5 5 0 Putative type VII ESX secretion system translocon, EccE POTRA_2 PF08479.11 KIK41783.1 - 0.1 12.5 0.0 13 5.7 0.0 4.2 5 0 0 5 5 5 0 POTRA domain, ShlB-type DUF2490 PF10677.9 KIK41783.1 - 3.2 7.6 4.0 30 4.5 0.0 4.2 6 1 0 6 6 5 0 Protein of unknown function (DUF2490) TPR_2 PF07719.17 KIK41783.1 - 6.7 7.1 24.4 8.7 6.7 0.0 10.9 15 0 0 15 15 12 0 Tetratricopeptide repeat WD40 PF00400.32 KIK41789.1 - 2.7e-34 116.6 18.0 3.4e-06 27.7 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41789.1 - 2.2e-10 40.7 0.5 0.089 13.1 0.0 4.9 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 KIK41789.1 - 0.029 14.1 0.1 0.072 12.8 0.1 1.6 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain PD40 PF07676.12 KIK41789.1 - 0.031 14.2 0.0 1.4e+02 2.6 0.0 4.8 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK41789.1 - 0.16 10.9 0.5 7.1 5.5 0.0 3.2 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK41789.1 - 0.26 10.6 0.0 0.51 9.6 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain Solute_trans_a PF03619.16 KIK41791.1 - 5.8e-84 281.7 15.3 6.8e-84 281.5 15.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Glycos_transf_4 PF00953.21 KIK41791.1 - 0.67 9.9 7.9 0.067 13.2 1.9 2.2 2 1 0 2 2 2 0 Glycosyl transferase family 4 Acid_PPase PF12689.7 KIK41794.1 - 3.4e-59 199.5 0.0 3.9e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase E1_dh PF00676.20 KIK41796.1 - 8.2e-81 271.2 0.0 9.6e-81 271.0 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component Spuma_A9PTase PF03539.14 KIK41796.1 - 0.18 11.9 0.3 0.3 11.2 0.3 1.3 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) DUF4448 PF14610.6 KIK41797.1 - 3.1e-06 27.1 0.1 4.9e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.9 KIK41797.1 - 0.01 16.6 4.9 0.015 16.0 2.2 2.4 1 1 1 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SKG6 PF08693.10 KIK41797.1 - 0.057 12.8 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pkinase_Tyr PF07714.17 KIK41798.1 - 6.2e-32 110.9 0.0 9.5e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK41798.1 - 6e-25 88.1 0.0 1e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KIK41798.1 - 0.00079 18.8 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KIK41798.1 - 0.0013 18.3 0.1 0.0064 16.1 0.0 2.1 2 1 0 2 2 2 1 RIO1 family FTA2 PF13095.6 KIK41798.1 - 0.14 11.7 0.0 0.4 10.3 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Rho_GDI PF02115.17 KIK41798.1 - 0.18 11.5 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 RHO protein GDP dissociation inhibitor PARP PF00644.20 KIK41799.1 - 1.9e-11 43.9 1.0 4.3e-11 42.8 0.7 1.7 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 KIK41799.1 - 4.8e-08 32.7 0.0 1.2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KIK41799.1 - 0.079 13.2 0.0 0.37 11.1 0.0 2.1 2 0 0 2 2 2 0 RWD domain ThrE PF06738.12 KIK41800.1 - 5.7e-52 176.5 23.5 4.9e-50 170.2 6.9 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KIK41800.1 - 1.2e-09 38.4 16.8 6.3e-09 36.1 3.7 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE DUF3915 PF13054.6 KIK41800.1 - 2.8 7.9 3.7 10 6.2 3.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) zf-C2HE PF16278.5 KIK41801.1 - 9.8e-15 54.8 0.2 9.8e-15 54.8 0.2 2.1 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 KIK41801.1 - 1.5e-13 51.2 1.3 2.6e-13 50.4 0.7 1.7 3 0 0 3 3 3 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KIK41801.1 - 4.9e-10 40.0 0.2 1e-09 39.0 0.2 1.5 1 0 0 1 1 1 1 HIT domain BicD PF09730.9 KIK41801.1 - 0.019 13.4 0.8 0.028 12.9 0.8 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D WD40 PF00400.32 KIK41805.1 - 3.3e-41 138.5 7.7 5.4e-08 33.4 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41805.1 - 7.9e-09 35.7 0.3 2.4 8.5 0.0 5.2 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK41805.1 - 0.00028 20.7 0.8 16 5.5 0.0 5.0 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ret2_MD PF18528.1 KIK41805.1 - 0.00086 19.6 0.0 14 6.1 0.0 3.5 2 1 0 3 3 3 1 RNA editing 3' terminal uridylyl transferase 2 middle domain Cytochrom_D1 PF02239.16 KIK41805.1 - 0.0022 16.6 0.4 0.14 10.7 0.1 2.1 1 1 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 KIK41805.1 - 0.022 13.4 2.5 0.11 11.1 0.1 2.8 3 1 1 4 4 4 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK41805.1 - 0.032 13.5 0.0 5.9 6.1 0.0 3.2 3 1 0 3 3 3 0 WD40-like domain WD40 PF00400.32 KIK41808.1 - 5.8e-26 90.2 5.3 1.9e-06 28.5 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41808.1 - 4.1e-07 30.2 0.3 0.022 15.0 0.0 3.6 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK41808.1 - 0.041 12.9 0.1 3 6.7 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein F-box-like PF12937.7 KIK41809.1 - 6.1e-08 32.4 2.9 1.3e-07 31.3 2.9 1.6 1 1 0 1 1 1 1 F-box-like DDHD PF02862.17 KIK41810.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 DDHD domain WD40 PF00400.32 KIK41812.1 - 1.3e-21 76.5 2.7 1.7e-08 34.9 0.9 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41812.1 - 0.00047 20.4 0.3 1 9.7 0.1 2.8 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK41812.1 - 0.015 14.0 0.3 0.073 11.7 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK41812.1 - 0.026 13.9 0.0 2.6 7.3 0.0 2.6 2 1 1 3 3 3 0 WD40-like domain PD40 PF07676.12 KIK41812.1 - 0.027 14.4 0.0 3.5 7.7 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat S1 PF00575.23 KIK41814.1 - 3.7e-12 46.4 0.1 7.2e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 KIK41814.1 - 1.5e-09 38.1 0.1 2.6e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 KIK41814.1 - 0.0039 17.4 0.0 0.0055 16.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 AA_permease PF00324.21 KIK41815.1 - 8e-120 400.6 46.4 1e-119 400.3 46.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK41815.1 - 3.3e-36 125.0 51.5 3.8e-36 124.8 51.5 1.0 1 0 0 1 1 1 1 Amino acid permease Terpene_synth_C PF03936.16 KIK41817.1 - 0.0017 17.8 0.0 0.0024 17.3 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Asp PF00026.23 KIK41818.1 - 1e-42 146.7 12.3 5e-42 144.4 12.3 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK41818.1 - 3.6e-05 24.1 1.5 0.0017 18.6 0.2 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KIK41818.1 - 0.0048 16.7 0.2 0.032 14.0 0.0 2.2 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Methyltransf_15 PF09445.10 KIK41820.1 - 4.6e-36 123.9 0.0 6.4e-35 120.2 0.0 2.0 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KIK41820.1 - 8.9e-08 32.7 0.0 1.7e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK41820.1 - 7.1e-07 29.1 0.0 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 KIK41820.1 - 1.1e-05 25.2 0.1 0.00039 20.2 0.1 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 KIK41820.1 - 2.6e-05 24.0 0.0 6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 KIK41820.1 - 0.00012 21.9 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 KIK41820.1 - 0.00017 22.2 0.0 0.00034 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 KIK41820.1 - 0.0035 16.4 0.0 0.0046 16.0 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_18 PF12847.7 KIK41820.1 - 0.0042 17.0 0.0 0.011 15.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain N6_Mtase PF02384.16 KIK41820.1 - 0.021 14.1 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase PrmA PF06325.13 KIK41820.1 - 0.022 14.2 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.11 KIK41820.1 - 0.024 14.3 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) N6_N4_Mtase PF01555.18 KIK41820.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 DNA methylase Methyltransf_12 PF08242.12 KIK41820.1 - 0.18 12.5 0.0 0.4 11.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.18 KIK41821.1 - 0.00044 20.3 8.5 0.0017 18.4 8.5 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RCC1 PF00415.18 KIK41822.1 - 4.9e-46 155.1 11.2 8e-14 52.0 0.0 6.8 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KIK41822.1 - 2e-17 62.5 31.7 5.4e-07 29.2 1.3 6.5 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.29 KIK41822.1 - 4.6e-12 45.6 5.2 4.6e-12 45.6 5.2 2.1 2 0 0 2 2 2 1 PHD-finger C1_2 PF03107.16 KIK41822.1 - 0.053 13.8 1.0 0.053 13.8 1.0 2.0 2 0 0 2 2 2 0 C1 domain Prok-RING_1 PF14446.6 KIK41822.1 - 2.1 8.4 12.2 0.081 12.9 5.8 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_4 PF16866.5 KIK41822.1 - 4.7 7.4 8.6 27 4.9 8.2 2.6 2 1 0 2 2 2 0 PHD-finger WD40 PF00400.32 KIK41823.1 - 5.4e-133 429.0 50.9 3.3e-11 43.5 0.5 14.9 15 0 0 15 15 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41823.1 - 4.6e-48 161.4 0.0 0.048 13.9 0.0 14.3 1 1 12 14 14 14 13 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK41823.1 - 8.4e-38 130.1 5.3 0.013 14.4 0.0 13.9 7 3 7 14 14 14 11 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK41823.1 - 5.1e-14 51.8 27.1 1.5 8.9 0.0 13.2 14 0 0 14 14 14 5 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK41823.1 - 3.7e-13 49.0 4.0 0.33 9.5 0.0 9.5 6 2 3 11 11 11 4 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK41823.1 - 7.3e-11 41.9 0.0 7.6 5.8 0.0 8.8 8 3 2 10 10 10 3 WD40-like domain AAA_16 PF13191.6 KIK41823.1 - 1.6e-05 25.3 0.1 4.2e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain Frtz PF11768.8 KIK41823.1 - 0.00039 18.9 0.0 10 4.3 0.0 6.1 2 2 4 7 7 7 1 WD repeat-containing and planar cell polarity effector protein Fritz NACHT PF05729.12 KIK41823.1 - 0.00045 20.2 0.0 0.00082 19.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain WD40_3 PF15911.5 KIK41823.1 - 0.0011 19.0 4.9 13 5.8 0.0 7.0 10 1 1 11 11 6 0 WD domain, G-beta repeat PQQ_2 PF13360.6 KIK41823.1 - 0.0059 16.2 17.9 0.039 13.5 7.7 3.6 1 1 3 4 4 4 3 PQQ-like domain Parvo_NS1 PF01057.17 KIK41823.1 - 0.021 13.9 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Ret2_MD PF18528.1 KIK41823.1 - 0.066 13.6 0.0 54 4.3 0.0 5.1 5 0 0 5 5 5 0 RNA editing 3' terminal uridylyl transferase 2 middle domain NB-ARC PF00931.22 KIK41823.1 - 0.099 11.8 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 KIK41823.1 - 0.12 12.6 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Cuticle_4 PF15955.5 KIK41823.1 - 0.23 12.2 2.7 97 3.8 0.0 5.6 8 0 0 8 8 6 0 Cuticle protein CHAP PF05257.16 KIK41823.1 - 0.78 10.4 8.9 38 5.0 0.0 6.3 5 2 1 8 8 6 0 CHAP domain SSF PF00474.17 KIK41826.1 - 7.5e-26 90.9 26.8 1.4e-25 90.0 26.8 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family SQS_PSY PF00494.19 KIK41828.1 - 1.5e-39 136.1 0.1 6.4e-39 134.0 0.0 1.8 2 0 0 2 2 2 1 Squalene/phytoene synthase DUF1899 PF08953.11 KIK41829.1 - 7.5e-28 96.2 0.1 2e-27 94.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 KIK41829.1 - 1.5e-19 70.0 3.2 5.4e-06 27.0 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40_4 PF16300.5 KIK41829.1 - 3.5e-17 62.0 0.1 7.9e-17 60.9 0.1 1.7 1 0 0 1 1 1 1 Type of WD40 repeat ANAPC4_WD40 PF12894.7 KIK41829.1 - 4e-07 30.2 0.0 0.035 14.4 0.0 4.2 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK41829.1 - 0.26 10.2 0.0 2.2 7.1 0.0 2.3 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SLATT_6 PF18169.1 KIK41831.1 - 0.081 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 EF-1_beta_acid PF10587.9 KIK41831.1 - 0.36 11.3 0.1 0.36 11.3 0.1 2.3 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Ribonuc_red_sm PF00268.21 KIK41832.1 - 4.8e-25 88.6 2.3 2.3e-13 50.3 0.3 3.1 2 1 1 3 3 3 3 Ribonucleotide reductase, small chain Nfu_N PF08712.11 KIK41832.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Scaffold protein Nfu/NifU N terminal Plavaka PF18759.1 KIK41833.1 - 5.2e-117 390.7 0.0 7.4e-117 390.2 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase ABC_tran PF00005.27 KIK41834.1 - 1e-25 90.9 0.0 3.7e-25 89.0 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIK41834.1 - 4.4e-09 36.6 5.9 1.8e-05 24.7 0.5 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIK41834.1 - 2.1e-08 34.3 0.0 9.7e-05 22.2 0.1 2.2 1 1 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 KIK41834.1 - 5.1e-07 29.3 0.0 0.025 14.0 0.4 2.2 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIK41834.1 - 6.6e-05 23.5 0.0 0.00012 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIK41834.1 - 0.00094 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KIK41834.1 - 0.011 16.1 0.0 0.02 15.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KIK41834.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_27 PF13514.6 KIK41834.1 - 0.024 14.2 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KIK41834.1 - 0.033 14.3 0.1 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase G-alpha PF00503.20 KIK41834.1 - 0.037 13.2 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 KIK41834.1 - 0.083 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.6 KIK41834.1 - 0.086 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KIK41834.1 - 0.096 12.7 0.0 0.23 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KIK41834.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin SbcCD_C PF13558.6 KIK41834.1 - 0.12 12.7 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit HET PF06985.11 KIK41836.1 - 3e-11 43.9 7.2 1.4e-09 38.5 0.8 3.0 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) WD40 PF00400.32 KIK41837.1 - 1.3e-39 133.4 8.8 1e-08 35.7 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41837.1 - 7.8e-13 48.5 0.7 0.06 13.7 0.0 5.0 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK41837.1 - 6.1e-07 28.5 3.6 0.14 10.8 0.1 4.0 2 1 2 4 4 4 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK41837.1 - 2.2e-06 26.9 0.1 0.13 11.2 0.0 4.0 2 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_2 PF07719.17 KIK41837.1 - 0.00035 20.4 0.9 12 6.3 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK41837.1 - 0.0028 17.8 0.4 0.015 15.5 1.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 WD40_like PF17005.5 KIK41837.1 - 0.026 13.8 0.0 16 4.7 0.0 3.2 4 0 0 4 4 4 0 WD40-like domain Cytochrom_D1 PF02239.16 KIK41837.1 - 0.099 11.1 0.2 7.9 4.9 0.1 2.4 2 0 0 2 2 2 0 Cytochrome D1 heme domain ABC_tran PF00005.27 KIK41838.1 - 2.5e-24 86.3 0.0 8.6e-24 84.6 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIK41838.1 - 6.5e-10 39.3 1.3 0.00073 19.4 0.2 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIK41838.1 - 1.8e-06 27.9 0.0 0.00035 20.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 KIK41838.1 - 1.8e-06 27.5 0.0 0.029 13.8 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIK41838.1 - 0.0058 17.0 0.0 0.019 15.4 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KIK41838.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KIK41838.1 - 0.015 15.5 0.1 0.039 14.2 0.1 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KIK41838.1 - 0.016 15.7 0.1 0.034 14.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK41838.1 - 0.029 14.1 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 KIK41838.1 - 0.051 12.7 0.0 0.08 12.1 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Zeta_toxin PF06414.12 KIK41838.1 - 0.08 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.6 KIK41838.1 - 0.095 12.7 0.0 0.33 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK41838.1 - 0.096 13.0 0.0 0.42 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Nic96 PF04097.14 KIK41839.1 - 4.5e-152 507.7 0.0 5.7e-152 507.4 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 DUF4096 PF13340.6 KIK41839.1 - 0.036 14.3 0.3 14 6.0 0.0 3.1 2 1 1 3 3 3 0 Putative transposase of IS4/5 family (DUF4096) SesA PF17107.5 KIK41839.1 - 0.074 13.2 0.1 0.25 11.5 0.1 1.9 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases SMN PF06003.12 KIK41840.1 - 0.087 12.1 12.7 1.2 8.3 2.0 2.9 2 1 1 3 3 3 0 Survival motor neuron protein (SMN) NACHT PF05729.12 KIK41842.1 - 8.5e-11 42.0 0.0 1.6e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK41842.1 - 1.9e-08 34.9 0.1 3.3e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK41842.1 - 0.00054 20.3 0.0 0.0015 18.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KIK41842.1 - 0.0093 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 KIK41842.1 - 0.02 15.4 0.0 0.029 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK41842.1 - 0.033 14.6 0.0 0.067 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 KIK41842.1 - 0.035 14.1 0.1 0.72 9.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 KIK41842.1 - 0.037 13.3 0.3 0.068 12.4 0.3 1.5 1 1 1 2 2 2 0 KAP family P-loop domain APS_kinase PF01583.20 KIK41842.1 - 0.043 13.7 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.29 KIK41842.1 - 0.099 13.1 0.0 0.25 11.8 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KIK41842.1 - 0.13 12.4 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 KIK41842.1 - 0.14 12.2 0.0 0.37 10.9 0.0 1.7 1 1 1 2 2 2 0 Torsin Anti-TRAP PF15777.5 KIK41843.1 - 8.8e-05 22.4 3.7 15 5.6 0.0 9.0 9 4 1 10 10 10 1 Tryptophan RNA-binding attenuator protein inhibitory protein Glyphos_transf PF04464.14 KIK41843.1 - 0.022 13.8 1.0 20 4.0 0.0 4.0 4 0 0 4 4 4 0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Ribosomal_L34 PF00468.17 KIK41843.1 - 0.23 11.5 1.3 20 5.2 0.0 4.6 5 1 1 6 6 6 0 Ribosomal protein L34 Phage_holin_3_5 PF16085.5 KIK41846.1 - 0.059 13.5 0.5 0.11 12.7 0.5 1.4 1 0 0 1 1 1 0 Bacteriophage holin Hol, superfamily III DUF4133 PF13571.6 KIK41846.1 - 3.5 8.0 6.4 46 4.4 5.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4133) DOT1 PF08123.13 KIK41848.1 - 3.2e-63 213.0 0.0 4.3e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_11 PF08241.12 KIK41848.1 - 0.011 16.3 0.0 0.025 15.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KIK41848.1 - 0.013 16.2 0.0 0.028 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ras PF00071.22 KIK41850.1 - 5.6e-63 211.4 0.0 6.5e-63 211.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK41850.1 - 2.8e-33 114.7 0.1 4.6e-33 114.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK41850.1 - 5.3e-14 52.0 0.1 6.9e-14 51.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIK41850.1 - 8.8e-06 25.4 0.2 2.1e-05 24.2 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIK41850.1 - 5.1e-05 23.3 0.0 0.0002 21.4 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KIK41850.1 - 9.9e-05 21.8 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KIK41850.1 - 0.00013 21.9 0.0 0.29 11.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KIK41850.1 - 0.012 15.2 0.0 0.91 9.0 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B SRPRB PF09439.10 KIK41850.1 - 0.014 14.8 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KIK41850.1 - 0.027 14.9 0.0 0.039 14.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KIK41850.1 - 0.048 13.4 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 KIK41850.1 - 0.07 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 KIK41850.1 - 0.087 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Septin MCM PF00493.23 KIK41850.1 - 0.13 11.3 0.0 0.34 10.0 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain UvrD-helicase PF00580.21 KIK41851.1 - 1e-09 38.4 2.0 1.9e-07 30.9 0.0 2.9 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KIK41851.1 - 1.9e-09 37.4 0.0 5.6e-07 29.3 0.0 3.1 2 1 1 3 3 3 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KIK41851.1 - 9.1e-07 29.3 0.0 4.5e-06 27.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIK41851.1 - 2.7e-06 27.7 3.0 0.068 13.4 0.0 4.0 4 0 0 4 4 4 2 AAA domain UvrD_C_2 PF13538.6 KIK41851.1 - 1.5e-05 24.7 0.0 0.0094 15.8 0.0 2.8 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain TPR_2 PF07719.17 KIK41851.1 - 0.096 12.9 10.7 0.7 10.2 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat AAA_30 PF13604.6 KIK41851.1 - 0.14 11.9 0.1 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Dynactin_p22 PF07426.11 KIK41851.1 - 0.15 11.9 0.1 0.43 10.4 0.1 1.8 1 0 0 1 1 1 0 Dynactin subunit p22 TPR_1 PF00515.28 KIK41851.1 - 0.26 11.2 2.1 1.7 8.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat UvrD_C PF13361.6 KIK41852.1 - 2.6e-10 40.2 0.0 1.5e-06 27.8 0.0 2.9 2 1 1 3 3 3 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KIK41852.1 - 3.9e-10 39.8 0.2 1e-07 31.8 0.1 2.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KIK41852.1 - 7.9e-07 29.5 0.0 2.3e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KIK41852.1 - 1.4e-06 28.0 0.0 0.0074 16.1 0.0 3.4 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 KIK41852.1 - 0.019 15.2 0.0 1.6 9.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain TPR_2 PF07719.17 KIK41852.1 - 0.027 14.6 5.1 1.3 9.3 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK41852.1 - 0.036 13.9 0.3 1.7 8.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_12 PF13087.6 KIK41852.1 - 0.098 12.3 0.0 0.55 9.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIK41852.1 - 0.18 11.5 0.0 7.2 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Dynactin_p22 PF07426.11 KIK41852.1 - 0.58 10.0 3.7 0.2 11.5 0.4 1.9 2 0 0 2 2 2 0 Dynactin subunit p22 DUF2724 PF10893.8 KIK41853.1 - 8.7 6.3 11.5 26 4.8 0.4 4.0 2 2 1 3 3 3 0 Protein of unknown function (DUF2724) NACHT PF05729.12 KIK41854.1 - 1.6e-11 44.4 0.0 2.3e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK41854.1 - 1.4e-08 35.3 0.1 2.1e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK41854.1 - 0.00015 22.0 0.0 0.00039 20.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KIK41854.1 - 0.0022 18.4 0.0 0.0076 16.7 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 KIK41854.1 - 0.0024 17.2 0.1 0.0061 15.8 0.1 1.5 1 1 1 2 2 2 1 KAP family P-loop domain NB-ARC PF00931.22 KIK41854.1 - 0.0067 15.6 0.0 0.009 15.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 KIK41854.1 - 0.0093 16.1 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIK41854.1 - 0.016 15.8 0.0 0.029 14.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK41854.1 - 0.032 14.6 0.0 0.065 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.20 KIK41854.1 - 0.039 13.8 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase TetR_C_6 PF13977.6 KIK41854.1 - 0.09 13.0 0.0 0.33 11.2 0.0 1.9 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal BTB PF00651.31 KIK41855.1 - 0.061 13.5 0.0 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain Atracotoxin PF05353.11 KIK41856.1 - 0.0016 18.4 1.7 0.002 18.1 1.7 1.2 1 0 0 1 1 1 1 Delta Atracotoxin Toxin_12 PF07740.12 KIK41856.1 - 0.083 13.6 5.3 0.12 13.1 5.3 1.2 1 0 0 1 1 1 0 Ion channel inhibitory toxin Conotoxin_I2 PF17557.2 KIK41856.1 - 0.11 12.7 6.6 0.15 12.2 6.6 1.2 1 0 0 1 1 1 0 I2-superfamily conotoxins Peptidase_S9 PF00326.21 KIK41857.1 - 2.6e-31 108.8 0.0 4.5e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KIK41857.1 - 1.5e-07 31.3 0.0 0.0075 15.9 0.0 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KIK41857.1 - 1.1e-06 28.2 0.2 0.01 15.1 0.1 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 KIK41857.1 - 2.3e-05 24.1 0.0 5.4e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KIK41857.1 - 4e-05 23.5 0.1 0.011 15.6 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KIK41857.1 - 0.00011 22.0 0.2 0.0017 18.0 0.1 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KIK41857.1 - 0.0041 17.0 0.1 0.014 15.3 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 KIK41857.1 - 0.0047 15.6 0.4 0.31 9.7 0.4 2.3 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 KIK41857.1 - 0.012 16.2 0.0 0.043 14.4 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Esterase PF00756.20 KIK41857.1 - 0.088 12.4 0.2 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 Putative esterase PAF-AH_p_II PF03403.13 KIK41857.1 - 0.14 10.6 0.0 0.24 9.9 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Ribosomal_S27e PF01667.17 KIK41858.1 - 4.3e-27 93.6 3.9 5.1e-27 93.3 3.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 Mu-like_Com PF10122.9 KIK41858.1 - 0.066 12.7 1.9 6.3 6.3 0.5 2.3 1 1 1 2 2 2 0 Mu-like prophage protein Com BTG PF07742.12 KIK41859.1 - 6.4e-13 48.6 0.0 1.3e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 BTG family DUF1308 PF07000.11 KIK41860.1 - 2.3e-05 24.4 0.3 0.011 15.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1308) GAIN_A PF18619.1 KIK41860.1 - 0.026 14.7 0.2 0.077 13.2 0.2 1.8 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Sarcoglycan_2 PF05510.13 KIK41861.1 - 0.21 10.3 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Abhydrolase_6 PF12697.7 KIK41865.1 - 1.4e-08 35.6 0.4 2.8e-08 34.7 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KIK41865.1 - 0.00068 19.4 0.1 0.001 18.8 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 KIK41865.1 - 0.0026 17.5 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK41865.1 - 0.0057 16.2 0.0 0.0084 15.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KIK41865.1 - 0.046 13.0 0.0 0.072 12.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 SET PF00856.28 KIK41867.1 - 5.4e-20 72.4 0.1 5.4e-20 72.4 0.1 2.6 2 2 0 2 2 2 1 SET domain RRM_1 PF00076.22 KIK41867.1 - 4.8e-11 42.3 0.0 5.2e-09 35.8 0.0 2.7 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KIK41867.1 - 1.6e-07 30.9 0.2 6.3e-05 22.5 0.0 2.6 2 0 0 2 2 2 2 Histone lysine methyltransferase SET associated N-SET PF11764.8 KIK41867.1 - 7e-07 29.5 6.9 7e-07 29.5 6.9 3.7 3 1 1 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component N WD40 PF00400.32 KIK41868.1 - 3e-28 97.5 0.4 8e-07 29.7 0.1 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41868.1 - 5.8e-10 39.3 0.1 0.014 15.7 0.0 4.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK41868.1 - 1.3e-05 24.0 0.1 0.0031 16.2 0.0 2.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KIK41868.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.5 1 1 0 1 1 1 0 PQQ-like domain Nucleoporin_N PF08801.11 KIK41868.1 - 0.025 13.3 0.1 2.7 6.6 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like WD40_like PF17005.5 KIK41868.1 - 0.038 13.3 0.0 1.5 8.0 0.0 3.1 1 1 1 3 3 3 0 WD40-like domain Cytochrom_D1 PF02239.16 KIK41868.1 - 0.041 12.4 0.1 0.11 11.0 0.1 1.6 1 1 0 1 1 1 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KIK41868.1 - 0.15 11.0 0.3 4.5 6.1 0.1 2.6 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SNAP PF14938.6 KIK41871.1 - 3e-101 338.6 19.0 3.4e-101 338.4 19.0 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 KIK41871.1 - 0.00021 21.7 6.4 5.6 7.8 0.0 5.8 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIK41871.1 - 0.00037 20.7 15.6 0.0023 18.2 4.6 3.3 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK41871.1 - 0.001 18.9 5.2 1.6 9.0 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Spatacsin_C PF14649.6 KIK41871.1 - 0.15 11.2 8.1 5.7 6.0 8.0 2.6 1 1 0 1 1 1 0 Spatacsin C-terminus TPR_8 PF13181.6 KIK41871.1 - 0.18 12.1 8.6 0.47 10.8 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK41871.1 - 0.62 10.3 7.6 0.79 10.0 0.9 3.7 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KIK41871.1 - 2.6 8.4 16.6 13 6.2 0.1 6.2 6 1 1 8 8 8 0 Tetratricopeptide repeat NSF PF02071.20 KIK41871.1 - 5.3 8.3 14.2 7.6 7.8 0.0 6.3 6 0 0 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat SGT1 PF07093.11 KIK41873.1 - 5.1 5.4 10.6 5.8 5.2 10.6 1.0 1 0 0 1 1 1 0 SGT1 protein tRNA-synt_2b PF00587.25 KIK41874.1 - 4.7e-37 127.7 0.0 1.2e-36 126.3 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KIK41874.1 - 5.8e-19 68.3 4.7 5.8e-19 68.3 4.7 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain tRNA-synt_His PF13393.6 KIK41874.1 - 0.023 14.0 0.3 0.055 12.7 0.0 1.7 2 0 0 2 2 2 0 Histidyl-tRNA synthetase PriC PF07445.12 KIK41874.1 - 0.047 13.6 0.2 0.1 12.6 0.2 1.5 1 0 0 1 1 1 0 Primosomal replication protein priC eIF3_N PF09440.10 KIK41874.1 - 2.9 8.4 5.6 1.8 9.0 2.3 2.2 2 1 0 2 2 2 0 eIF3 subunit 6 N terminal domain GRDP-like PF07173.12 KIK41875.1 - 1.6e-22 80.7 0.6 5.7e-16 59.4 0.0 3.2 2 1 1 3 3 3 3 Glycine-rich domain-containing protein-like FAD_binding_3 PF01494.19 KIK41876.1 - 6.8e-22 78.2 0.0 4.6e-21 75.5 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIK41876.1 - 0.031 14.5 0.1 0.076 13.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KIK41876.1 - 0.052 12.4 1.2 0.25 10.1 0.1 2.3 2 1 1 3 3 3 0 Tryptophan halogenase FPV060 PF17614.2 KIK41876.1 - 0.19 11.1 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Viral CC-type chemokine FAD_binding_3 PF01494.19 KIK41877.1 - 9.2e-21 74.5 0.0 2.4e-19 69.8 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIK41877.1 - 0.0028 17.9 0.3 0.0062 16.7 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK41877.1 - 0.015 14.6 0.2 0.026 13.7 0.2 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIK41877.1 - 0.18 10.6 0.5 0.29 9.9 0.5 1.3 1 0 0 1 1 1 0 Tryptophan halogenase SE PF08491.10 KIK41877.1 - 0.21 10.6 0.0 3.6 6.6 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase IBR PF01485.21 KIK41878.1 - 7.3e-15 54.9 28.5 3.8e-09 36.6 6.3 3.2 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 KIK41878.1 - 5.5e-07 29.5 6.5 5.5e-07 29.5 6.5 3.2 3 0 0 3 3 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KIK41878.1 - 7e-06 26.1 5.9 7e-06 26.1 5.9 3.5 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KIK41878.1 - 1.2e-05 25.0 2.5 1.2e-05 25.0 2.5 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 KIK41878.1 - 1.4e-05 25.0 2.6 3.3e-05 23.8 2.6 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4 PF00097.25 KIK41878.1 - 2.1e-05 24.3 3.3 2.1e-05 24.3 3.3 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK41878.1 - 3.6e-05 23.5 3.0 3.6e-05 23.5 3.0 4.4 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK41878.1 - 8.7e-05 22.8 4.0 8.7e-05 22.8 4.0 3.7 3 0 0 3 3 3 1 Ring finger domain zf-CCCH PF00642.24 KIK41878.1 - 0.00038 20.3 0.8 0.00093 19.1 0.8 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KIK41878.1 - 0.00087 19.0 0.7 0.002 17.9 0.7 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 KIK41878.1 - 0.019 15.6 0.3 0.057 14.1 0.3 1.8 1 0 0 1 1 1 0 Torus domain KH_1 PF00013.29 KIK41878.1 - 0.049 13.5 0.0 6 6.8 0.0 2.8 2 0 0 2 2 2 0 KH domain Ribonuc_2-5A PF06479.12 KIK41879.1 - 1.6e-45 154.3 0.1 3.4e-45 153.3 0.1 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 KIK41879.1 - 6.3e-39 133.9 0.0 1.9e-31 109.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK41879.1 - 2.6e-19 69.5 0.0 3.7e-18 65.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK41879.1 - 1.4e-06 27.4 0.0 4.9e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase PQQ PF01011.21 KIK41879.1 - 5.6e-06 26.0 0.0 0.0035 17.2 0.0 2.7 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.6 KIK41879.1 - 0.00052 19.7 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 PQQ-like domain Kdo PF06293.14 KIK41879.1 - 0.0067 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 KIK41880.1 - 3.6e-10 40.3 10.9 0.058 14.3 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat WD40_like PF17005.5 KIK41880.1 - 0.034 13.5 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain Aldedh PF00171.22 KIK41881.1 - 6.6e-121 404.0 0.0 7.6e-121 403.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4342 PF14242.6 KIK41881.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) HAUS-augmin3 PF14932.6 KIK41882.1 - 0.0086 15.7 1.9 0.03 13.9 0.9 1.9 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 3 WD40 PF00400.32 KIK41884.1 - 3e-34 116.5 15.7 1.9e-08 34.8 0.1 8.9 7 1 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 KIK41884.1 - 4.5e-10 39.3 0.4 1.2e-09 37.9 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK41884.1 - 6.5e-09 35.5 1.1 1.8e-08 34.1 1.1 1.8 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KIK41884.1 - 0.0011 19.2 0.0 6.2 7.2 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK41884.1 - 0.0055 16.1 0.0 1.1 8.5 0.0 2.6 2 1 0 2 2 2 2 WD40-like domain RAP1 PF07218.11 KIK41884.1 - 1.6 6.9 3.1 2.4 6.3 3.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Vps26 PF03643.15 KIK41888.1 - 0.0055 15.8 0.0 0.0074 15.3 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Plavaka PF18759.1 KIK41889.1 - 1.5e-37 129.6 0.0 2.4e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase SDA1 PF05285.12 KIK41889.1 - 0.16 11.4 3.8 0.23 10.9 3.8 1.2 1 0 0 1 1 1 0 SDA1 Exo_endo_phos PF03372.23 KIK41890.1 - 0.00094 18.8 0.1 0.0012 18.4 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Rubrerythrin PF02915.17 KIK41891.1 - 0.0046 17.4 1.0 0.0046 17.4 1.0 2.0 2 0 0 2 2 2 1 Rubrerythrin BAR_3 PF16746.5 KIK41891.1 - 9.9 5.8 15.0 0.098 12.3 4.5 2.4 3 0 0 3 3 3 0 BAR domain of APPL family DB PF01682.19 KIK41894.1 - 0.023 15.0 0.3 0.066 13.5 0.3 1.7 1 0 0 1 1 1 0 DB module MerR-DNA-bind PF09278.11 KIK41894.1 - 0.027 15.0 0.1 1.6 9.3 0.0 2.8 2 0 0 2 2 2 0 MerR, DNA binding SKA1 PF07160.12 KIK41894.1 - 0.34 10.7 5.8 0.67 9.8 5.8 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Fez1 PF06818.15 KIK41894.1 - 6.9 7.1 12.4 13 6.1 12.4 1.6 1 1 0 1 1 1 0 Fez1 Swi5 PF07061.11 KIK41894.1 - 7.9 6.7 6.1 5 7.3 3.0 2.3 2 0 0 2 2 2 0 Swi5 MIF4G PF02854.19 KIK41895.1 - 1.6e-23 83.5 2.5 3.8e-23 82.2 2.5 1.7 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 KIK41895.1 - 8.2e-20 70.9 1.9 1.4e-19 70.1 0.0 2.5 4 0 0 4 4 4 1 MA3 domain CDV3 PF15359.6 KIK41895.1 - 0.011 16.3 2.2 0.011 16.3 2.2 2.5 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Methyltransf_31 PF13847.6 KIK41896.1 - 2.5e-18 66.3 0.0 3.2e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK41896.1 - 4.7e-08 33.7 0.0 9.9e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK41896.1 - 2.8e-07 31.2 0.0 6.1e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK41896.1 - 3.8e-07 30.1 0.0 5.5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK41896.1 - 5.7e-05 23.7 0.0 0.00031 21.3 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 KIK41896.1 - 0.02 14.9 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KIK41896.1 - 0.065 13.0 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 KIK41896.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase MTS PF05175.14 KIK41896.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain Pam16 PF03656.13 KIK41897.1 - 0.00095 19.2 0.0 0.0011 19.0 0.0 1.3 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 KIK41897.1 - 0.0017 18.4 0.0 0.0025 17.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Dyp_perox PF04261.12 KIK41897.1 - 0.032 13.2 0.0 0.034 13.1 0.0 1.0 1 0 0 1 1 1 0 Dyp-type peroxidase family AAA_11 PF13086.6 KIK41898.1 - 3.7e-24 85.9 0.2 1.8e-12 47.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KIK41898.1 - 2.4e-17 63.3 0.0 1e-16 61.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK41898.1 - 4.4e-15 56.3 0.0 1.3e-14 54.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KIK41898.1 - 9.1e-09 35.5 0.1 3.1e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KIK41898.1 - 0.00011 22.6 0.0 0.0003 21.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.16 KIK41898.1 - 0.00022 20.8 1.1 0.004 16.6 0.0 2.8 2 1 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 KIK41898.1 - 0.00039 19.6 0.0 0.0032 16.6 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein Helicase_RecD PF05127.14 KIK41898.1 - 0.00091 19.1 0.0 0.0067 16.3 0.0 2.3 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 KIK41898.1 - 0.0021 17.6 1.0 0.03 13.8 0.0 2.6 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 KIK41898.1 - 0.005 16.1 0.0 0.014 14.7 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 KIK41898.1 - 0.0056 17.1 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KIK41898.1 - 0.008 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Viral_helicase1 PF01443.18 KIK41898.1 - 0.013 15.2 0.6 1.5 8.5 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 KIK41898.1 - 0.013 15.2 0.1 0.067 13.0 0.1 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase Rad17 PF03215.15 KIK41898.1 - 0.016 15.1 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 KIK41898.1 - 0.016 15.5 0.0 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KIK41898.1 - 0.018 14.6 0.0 0.043 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KIK41898.1 - 0.04 13.8 0.1 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 KIK41898.1 - 0.058 13.1 0.1 0.19 11.5 0.0 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KIK41898.1 - 0.12 11.7 0.0 0.46 9.7 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 KIK41898.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI zf-C2H2_2 PF12756.7 KIK41900.1 - 0.025 14.9 0.5 0.044 14.1 0.5 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) AAA_12 PF13087.6 KIK41901.1 - 3.4e-26 92.1 0.1 7.8e-26 90.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK41901.1 - 4.1e-22 79.2 0.2 2.5e-12 47.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KIK41901.1 - 4.4e-18 65.7 0.0 1.9e-17 63.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK41901.1 - 5e-14 52.9 0.0 1.3e-13 51.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KIK41901.1 - 2.3e-07 31.0 0.0 5.1e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KIK41901.1 - 2.9e-05 24.5 0.0 9.5e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KIK41901.1 - 0.00034 19.9 0.0 0.00073 18.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain T2SSE PF00437.20 KIK41901.1 - 0.0013 17.9 0.0 0.0029 16.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.29 KIK41901.1 - 0.002 17.9 0.0 0.0084 15.9 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 KIK41901.1 - 0.0021 17.4 0.0 0.005 16.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 KIK41901.1 - 0.0036 17.2 0.0 0.021 14.7 0.0 2.2 1 1 0 1 1 1 1 Helicase PhoH PF02562.16 KIK41901.1 - 0.0043 16.5 0.0 0.24 10.8 0.0 2.7 3 0 0 3 3 3 1 PhoH-like protein AAA_22 PF13401.6 KIK41901.1 - 0.014 15.7 0.0 0.054 13.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KIK41901.1 - 0.026 14.9 0.0 0.093 13.2 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 KIK41901.1 - 0.034 14.0 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein ATPase_2 PF01637.18 KIK41901.1 - 0.035 14.0 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PIF1 PF05970.14 KIK41901.1 - 0.037 13.2 0.0 0.084 12.0 0.0 1.6 1 0 0 1 1 1 0 PIF1-like helicase Rad17 PF03215.15 KIK41901.1 - 0.047 13.6 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain UvrD-helicase PF00580.21 KIK41901.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain IstB_IS21 PF01695.17 KIK41901.1 - 0.08 12.7 0.0 0.63 9.8 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Ploopntkinase3 PF18751.1 KIK41901.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 V-set PF07686.17 KIK41901.1 - 0.11 12.7 0.0 3 8.0 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin V-set domain AAA_11 PF13086.6 KIK41902.1 - 2.8e-13 50.3 0.9 2.2e-12 47.3 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIK41902.1 - 7.5e-10 38.8 0.1 2e-09 37.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK41902.1 - 2.1e-06 28.2 0.1 1.4e-05 25.6 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 KIK41902.1 - 1e-05 25.9 0.1 2.4e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KIK41902.1 - 0.0023 18.0 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIK41902.1 - 0.0037 17.5 0.2 0.014 15.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 KIK41902.1 - 0.0097 15.3 1.7 0.011 15.0 0.0 1.9 3 0 0 3 3 3 1 KaiC Helicase_RecD PF05127.14 KIK41902.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Helicase NB-ARC PF00931.22 KIK41902.1 - 0.016 14.4 0.2 0.3 10.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 KIK41902.1 - 0.016 15.1 0.1 0.036 14.0 0.1 1.7 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 KIK41902.1 - 0.017 15.0 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA PF00004.29 KIK41902.1 - 0.026 14.9 0.1 0.065 13.7 0.1 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KIK41902.1 - 0.031 13.3 0.1 0.075 12.1 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.16 KIK41902.1 - 0.035 13.6 0.1 0.075 12.5 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 KIK41902.1 - 0.092 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 KIK41902.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 KIK41902.1 - 0.12 12.0 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK41902.1 - 0.13 12.1 0.4 0.32 10.8 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 KIK41902.1 - 0.17 11.6 0.1 0.34 10.6 0.1 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PIF1 PF05970.14 KIK41902.1 - 0.17 11.0 0.5 0.41 9.8 0.1 1.7 2 0 0 2 2 2 0 PIF1-like helicase TsaE PF02367.17 KIK41902.1 - 0.18 11.8 0.1 0.45 10.5 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KIK41902.1 - 0.19 11.3 0.3 0.36 10.4 0.3 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KIK41902.1 - 0.23 12.0 0.9 0.45 11.0 0.1 1.9 2 0 0 2 2 1 0 ABC transporter AAA_12 PF13087.6 KIK41903.1 - 5.7e-18 65.3 0.0 9e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF4392 PF14336.6 KIK41903.1 - 0.15 11.4 0.0 0.33 10.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) Carn_acyltransf PF00755.20 KIK41904.1 - 1.6e-147 492.7 0.0 1.8e-147 492.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase RMI1_N PF08585.12 KIK41905.1 - 3.4e-26 92.4 0.0 4e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 RecQ mediated genome instability protein Methyltransf_25 PF13649.6 KIK41907.1 - 0.00093 19.9 0.0 0.0046 17.6 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK41907.1 - 0.025 15.2 0.0 0.053 14.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KIK41907.1 - 0.08 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KIK41908.1 - 0.0017 19.0 0.0 0.0065 17.1 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK41908.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KIK41908.1 - 0.12 13.0 0.0 0.24 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DnaJ PF00226.31 KIK41909.1 - 5.8e-14 52.0 0.3 1.3e-13 50.9 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain Nif11 PF07862.11 KIK41909.1 - 0.041 14.2 0.7 0.087 13.1 0.1 1.9 2 0 0 2 2 2 0 Nif11 domain GSK-3_bind PF05350.12 KIK41909.1 - 0.11 11.8 1.1 0.13 11.5 0.3 1.7 1 1 0 1 1 1 0 Glycogen synthase kinase-3 binding CtaG_Cox11 PF04442.14 KIK41910.1 - 1.7e-59 200.1 0.0 2.4e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DUF155 PF02582.14 KIK41911.1 - 2.7e-45 154.6 0.0 3.8e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 p450 PF00067.22 KIK41912.1 - 3.1e-41 141.6 0.0 3.2e-40 138.3 0.0 2.0 1 1 0 2 2 2 1 Cytochrome P450 Slp PF03843.13 KIK41912.1 - 0.17 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family SART-1 PF03343.13 KIK41913.1 - 1.6e-164 549.0 50.7 1.6e-164 549.0 50.7 1.9 2 0 0 2 2 2 2 SART-1 family p450 PF00067.22 KIK41914.1 - 2.4e-78 263.9 0.0 3e-78 263.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CBFD_NFYB_HMF PF00808.23 KIK41917.1 - 4.8e-07 30.0 0.1 8.9e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KIK41917.1 - 0.011 15.9 0.1 0.016 15.3 0.1 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Pkinase_Tyr PF07714.17 KIK41919.1 - 7.3e-33 113.9 0.0 8.2e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK41919.1 - 2e-26 92.9 0.0 2.4e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK41919.1 - 0.001 18.5 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIK41919.1 - 0.0071 16.0 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KIK41919.1 - 0.031 13.1 0.0 0.041 12.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KIK41919.1 - 0.033 14.1 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK41919.1 - 0.033 13.5 0.0 0.048 13.0 0.0 1.3 1 1 0 1 1 1 0 Kinase-like FGGY_C PF02782.16 KIK41920.1 - 9.6e-50 169.1 0.0 1.4e-49 168.5 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KIK41920.1 - 5e-16 59.0 0.5 3.6e-15 56.2 0.5 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KIK41920.1 - 0.0036 16.8 1.0 0.11 12.0 0.2 2.3 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family AnmK PF03702.14 KIK41920.1 - 0.011 14.8 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Anhydro-N-acetylmuramic acid kinase Hexokinase_1 PF00349.21 KIK41920.1 - 0.038 13.9 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 Hexokinase DUF3142 PF11340.8 KIK41921.1 - 0.052 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) XPG_N PF00752.17 KIK41922.1 - 4.8e-34 116.9 0.0 1.1e-33 115.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KIK41922.1 - 5.9e-27 93.9 0.0 1.6e-26 92.5 0.0 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 KIK41922.1 - 1.7e-06 28.6 0.0 5.1e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.16 KIK41922.1 - 0.093 12.6 0.0 0.29 11.0 0.0 1.7 1 1 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain DUF3787 PF12655.7 KIK41922.1 - 2.2 8.3 8.4 0.85 9.6 2.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3787) zf-C2H2_4 PF13894.6 KIK41923.1 - 0.049 14.5 0.1 0.15 12.9 0.1 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Baculo_gp64 PF03273.13 KIK41924.1 - 0.052 12.3 0.0 0.052 12.3 0.0 1.0 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family Na_H_Exchanger PF00999.21 KIK41927.1 - 1e-63 215.5 26.0 1.2e-63 215.2 26.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family RRM_1 PF00076.22 KIK41928.1 - 2.7e-10 39.9 0.2 0.0038 17.0 0.0 4.6 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HET PF06985.11 KIK41929.1 - 0.00051 20.4 0.3 0.00069 20.0 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Yip1 PF04893.17 KIK41931.1 - 0.011 15.4 1.5 0.026 14.2 1.5 1.6 1 1 0 1 1 1 0 Yip1 domain BRX_N PF13713.6 KIK41931.1 - 0.079 12.7 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain Oxidored_q3 PF00499.20 KIK41931.1 - 0.1 12.3 0.1 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Abhydrolase_3 PF07859.13 KIK41933.1 - 2.9e-17 63.2 0.0 1.1e-12 48.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK41933.1 - 1.7e-07 30.9 0.0 0.0022 17.5 0.0 2.4 3 0 0 3 3 3 2 Prolyl oligopeptidase family COesterase PF00135.28 KIK41933.1 - 5.7e-07 28.8 0.0 0.00011 21.3 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_6 PF12697.7 KIK41933.1 - 5.9e-06 27.1 0.7 1.2e-05 26.0 0.7 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KIK41933.1 - 0.0056 16.3 0.0 1.8 8.1 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KIK41933.1 - 0.14 11.7 0.1 2.6 7.6 0.1 2.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KIK41933.1 - 0.18 11.3 0.2 2.1 7.8 0.0 2.5 3 1 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) TAF PF02969.17 KIK41934.1 - 1.7e-25 89.0 0.3 3.1e-25 88.1 0.3 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 KIK41934.1 - 7.5e-16 58.2 0.1 2.2e-15 56.8 0.1 1.8 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 KIK41934.1 - 2.2e-05 24.8 0.2 2.2e-05 24.8 0.2 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIK41934.1 - 0.00037 20.6 0.0 0.00086 19.4 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KIK41934.1 - 0.0015 18.5 0.0 0.0049 16.9 0.0 1.8 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.6 KIK41934.1 - 0.0051 17.2 0.2 0.012 16.0 0.2 1.6 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIK41934.1 - 0.009 16.3 0.1 0.02 15.2 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HEAT_2 PF13646.6 KIK41934.1 - 0.012 16.0 0.4 0.43 11.0 0.0 3.0 2 1 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.6 KIK41934.1 - 0.022 15.3 4.4 0.27 11.8 0.0 4.0 2 2 2 4 4 4 0 HEAT-like repeat Urb2 PF10441.9 KIK41934.1 - 0.023 14.7 0.4 0.023 14.7 0.4 1.9 3 0 0 3 3 3 0 Urb2/Npa2 family Sec7_N PF12783.7 KIK41934.1 - 0.075 12.9 0.1 0.79 9.6 0.0 2.1 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal CENP-T_C PF15511.6 KIK41934.1 - 0.22 11.6 1.1 0.53 10.4 0.1 2.1 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold Mito_carr PF00153.27 KIK41935.1 - 1.1e-56 188.7 7.2 8.2e-19 67.3 0.1 4.0 2 1 2 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 KIK41935.1 - 0.0013 18.0 1.0 0.061 12.5 0.2 2.8 2 1 1 3 3 3 2 Gammaproteobacterial serine protease tRNA_int_end_N2 PF12928.7 KIK41936.1 - 5.6e-22 77.7 0.0 1e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 KIK41936.1 - 0.0023 17.5 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Glyco_hydro_88 PF07470.13 KIK41937.1 - 1.3e-14 54.1 0.0 1.6e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 CRAL_TRIO_2 PF13716.6 KIK41938.1 - 2.9e-30 105.2 0.2 5.1e-30 104.4 0.2 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 KIK41938.1 - 9e-30 103.5 0.0 1.6e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.20 KIK41938.1 - 5.6e-05 22.9 0.1 0.00026 20.8 0.1 2.0 1 1 0 1 1 1 1 CRAL/TRIO domain AMP-binding PF00501.28 KIK41939.1 - 1.5e-75 254.5 0.0 1.9e-75 254.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK41939.1 - 7.5e-07 30.0 0.0 2e-06 28.7 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KIK41940.1 - 1.6e-57 195.0 0.0 2.1e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK41940.1 - 5e-05 24.2 0.0 0.00012 22.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KIK41941.1 - 5e-71 239.5 0.0 6.4e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK41941.1 - 0.00015 22.7 0.0 0.00029 21.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TPR_10 PF13374.6 KIK41943.1 - 3.6e-40 134.8 38.4 2.6e-05 24.0 0.1 11.6 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_14 PF13428.6 KIK41943.1 - 5.1e-21 73.6 40.2 0.31 12.0 0.8 12.3 11 1 1 12 12 12 8 Tetratricopeptide repeat TPR_12 PF13424.6 KIK41943.1 - 2.8e-19 69.2 35.8 0.012 15.9 2.0 11.5 3 1 8 11 11 11 8 Tetratricopeptide repeat TPR_1 PF00515.28 KIK41943.1 - 3.3e-16 58.3 38.3 0.071 13.0 0.1 12.0 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_2 PF07719.17 KIK41943.1 - 1.6e-12 46.5 44.6 0.21 11.8 0.4 12.1 13 0 0 13 13 12 7 Tetratricopeptide repeat TPR_8 PF13181.6 KIK41943.1 - 4.4e-11 42.1 12.3 2.4 8.6 0.0 10.7 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK41943.1 - 4e-10 39.0 17.1 1.1 9.5 0.0 10.9 11 1 0 11 11 10 1 Tetratricopeptide repeat GATase_4 PF13230.6 KIK41943.1 - 1.1e-09 37.6 0.1 2.7 6.8 0.0 6.8 2 2 6 8 8 8 2 Glutamine amidotransferases class-II TPR_11 PF13414.6 KIK41943.1 - 6.8e-08 32.1 23.6 0.076 12.7 0.1 9.7 10 0 0 10 10 10 2 TPR repeat DUF4471 PF14740.6 KIK41943.1 - 1.6e-07 30.8 0.0 21 4.2 0.0 7.3 9 0 0 9 9 9 0 Domain of unknown function (DUF4471) Fer4_13 PF13370.6 KIK41943.1 - 1.6e-06 28.6 2.3 27 5.4 0.0 6.1 6 0 0 6 6 6 0 4Fe-4S single cluster domain of Ferredoxin I TPR_16 PF13432.6 KIK41943.1 - 9.4e-06 26.2 47.3 0.077 13.7 2.3 10.0 6 2 4 10 10 10 5 Tetratricopeptide repeat TPR_17 PF13431.6 KIK41943.1 - 7.1e-05 22.9 8.1 3.6 8.2 0.0 8.1 8 1 0 9 9 9 1 Tetratricopeptide repeat CD225 PF04505.12 KIK41943.1 - 0.001 19.2 0.0 65 3.8 0.0 5.7 5 1 1 6 6 6 0 Interferon-induced transmembrane protein DUF4253 PF14062.6 KIK41943.1 - 0.0037 17.4 0.6 9.1 6.5 0.0 4.8 4 1 1 5 5 5 0 Domain of unknown function (DUF4253) TPR_19 PF14559.6 KIK41943.1 - 0.0075 16.8 29.8 22 5.7 0.1 11.0 13 0 0 13 13 12 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KIK41943.1 - 0.0077 16.3 19.1 3.4 7.8 0.1 8.2 4 2 5 9 9 8 1 Anaphase-promoting complex subunit 5 Dehydratase_SU PF02287.15 KIK41943.1 - 0.011 15.8 0.2 5.1 7.2 0.0 4.7 4 1 2 6 6 6 0 Dehydratase small subunit Exonuc_VII_S PF02609.16 KIK41943.1 - 0.017 15.2 15.1 14 5.8 0.0 9.0 11 0 0 11 11 10 0 Exonuclease VII small subunit FRB_dom PF08771.11 KIK41943.1 - 0.022 15.2 0.2 88 3.6 0.0 5.9 9 0 0 9 9 7 0 FKBP12-rapamycin binding domain TOM20_plant PF06552.12 KIK41943.1 - 0.025 14.3 0.0 2.7 7.7 0.0 3.1 2 1 2 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 Syntaxin-6_N PF09177.11 KIK41943.1 - 0.088 13.4 0.2 46 4.6 0.0 4.2 2 2 2 4 4 4 0 Syntaxin 6, N-terminal DUF2989 PF11207.8 KIK41943.1 - 0.2 11.4 0.1 25 4.5 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2989) WD40 PF00400.32 KIK41944.1 - 1.9e-20 72.8 11.1 7.6e-09 36.1 2.5 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41944.1 - 1.3e-14 54.2 1.6 2.9e-05 24.3 0.1 4.5 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK41944.1 - 8.7e-06 24.9 0.1 0.22 10.5 0.0 3.2 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK41944.1 - 9.7e-06 25.4 0.1 0.95 9.5 0.1 4.0 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 KIK41944.1 - 0.0036 16.9 3.8 0.058 13.0 3.8 2.1 1 1 0 1 1 1 1 PQQ-like domain DPPIV_N PF00930.21 KIK41944.1 - 0.013 14.3 0.1 12 4.6 0.0 3.5 3 2 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nup160 PF11715.8 KIK41944.1 - 0.02 13.5 1.7 12 4.4 0.0 3.6 1 1 3 4 4 4 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KIK41944.1 - 0.029 14.9 5.6 0.66 10.5 1.4 3.4 3 1 0 3 3 3 0 PQQ-like domain WD40_like PF17005.5 KIK41944.1 - 0.096 12.0 0.0 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain CHAT PF12770.7 KIK41946.1 - 1.2e-21 77.4 0.4 8.6e-21 74.6 0.4 2.1 1 1 0 1 1 1 1 CHAT domain Zeta_toxin PF06414.12 KIK41946.1 - 0.19 11.0 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin WD40 PF00400.32 KIK41947.1 - 1e-24 86.3 18.1 1.3e-09 38.5 0.2 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK41947.1 - 3.5e-14 52.9 1.1 0.0013 19.0 0.0 6.0 2 2 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK41947.1 - 1.1e-06 27.7 0.1 0.12 11.0 0.0 3.9 2 1 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK41947.1 - 6.3e-05 22.9 0.1 0.38 10.6 0.0 3.0 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK41947.1 - 0.00034 19.7 0.1 3.7 6.4 0.0 3.8 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 KIK41947.1 - 0.0036 17.8 1.1 45 4.7 0.0 5.2 5 1 0 5 5 5 0 PQQ-like domain PD40 PF07676.12 KIK41947.1 - 0.017 15.0 3.1 40 4.3 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PQQ PF01011.21 KIK41947.1 - 0.026 14.5 0.0 8.6 6.5 0.0 3.8 4 0 0 4 4 4 0 PQQ enzyme repeat Phosphorylase PF00343.20 KIK41948.1 - 4.5e-300 997.1 0.0 5.2e-300 996.9 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF1708 PF08101.11 KIK41949.1 - 2.9e-21 76.1 0.0 2.2e-20 73.3 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.27 KIK41949.1 - 0.045 13.6 0.0 0.25 11.2 0.0 2.2 1 1 0 1 1 1 0 RhoGAP domain DUF4834 PF16118.5 KIK41951.1 - 0.15 13.0 0.0 0.31 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF1687 PF07955.11 KIK41952.1 - 2.5e-17 63.5 0.0 3.8e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) STE PF02200.16 KIK41953.1 - 1.6e-54 183.0 0.0 2.7e-54 182.3 0.0 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 KIK41953.1 - 2.2e-09 37.2 10.4 8.5e-05 22.8 1.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK41953.1 - 1.8e-07 31.2 13.1 3.8e-07 30.2 3.5 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK41953.1 - 2.9e-07 30.7 8.9 0.0021 18.8 0.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KIK41953.1 - 8.5e-05 22.8 1.8 8.5e-05 22.8 1.8 2.3 2 0 0 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KIK41953.1 - 0.0016 18.7 1.6 0.079 13.3 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KIK41953.1 - 0.0016 18.4 0.2 0.0016 18.4 0.2 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 KIK41953.1 - 0.0037 17.6 3.2 0.0039 17.5 0.4 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KIK41953.1 - 0.79 10.2 6.0 3.1 8.3 0.7 2.7 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 KIK41953.1 - 1.9 8.3 10.7 1.7 8.5 0.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain EAP30 PF04157.16 KIK41955.1 - 8.7e-37 126.7 0.0 1.2e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KIK41955.1 - 4e-17 62.2 0.0 7e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 DZR PF12773.7 KIK41955.1 - 0.0027 17.7 5.1 0.02 14.9 0.4 2.3 2 0 0 2 2 2 1 Double zinc ribbon zf-RanBP PF00641.18 KIK41955.1 - 0.0033 16.7 11.8 0.0085 15.4 1.5 2.6 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 KIK41955.1 - 0.0098 15.9 4.7 1.9 8.6 0.1 2.9 3 0 0 3 3 3 2 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 KIK41955.1 - 0.025 14.0 0.3 0.025 14.0 0.3 2.7 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF2993 PF11209.8 KIK41955.1 - 0.085 13.1 0.2 0.15 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2993) SRP9-21 PF05486.12 KIK41956.1 - 4.2e-11 43.1 0.9 1.6e-09 38.0 0.9 2.3 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Pou PF00157.17 KIK41956.1 - 0.054 13.5 0.0 0.078 13.0 0.0 1.2 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain Mito_carr PF00153.27 KIK41957.1 - 2.3e-60 200.5 1.5 1.9e-21 75.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peroxidase_2 PF01328.17 KIK41958.1 - 1.1e-51 176.1 0.0 1.3e-51 175.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 PigN PF04987.14 KIK41959.1 - 2e-130 435.7 35.3 2.5e-130 435.4 35.3 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KIK41959.1 - 4.3e-09 36.4 2.2 2.1e-08 34.2 2.2 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KIK41959.1 - 6.7e-05 22.4 0.1 9.1e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KIK41959.1 - 0.0072 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily AreA_N PF07573.11 KIK41959.1 - 0.11 13.2 0.0 0.26 12.0 0.0 1.6 1 0 0 1 1 1 0 Nitrogen regulatory protein AreA N terminus ATP-synt_C PF00137.21 KIK41960.1 - 6.9e-16 58.3 11.6 6.9e-16 58.3 11.6 1.6 2 0 0 2 2 2 1 ATP synthase subunit C TauE PF01925.19 KIK41960.1 - 0.0018 17.9 7.2 0.0024 17.5 7.2 1.1 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE F-box-like PF12937.7 KIK41961.1 - 0.001 18.9 1.2 0.01 15.7 1.2 2.5 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIK41962.1 - 0.022 14.6 0.6 0.063 13.2 0.6 1.8 1 0 0 1 1 1 0 F-box-like OTU PF02338.19 KIK41963.1 - 2.5e-13 50.6 0.0 4.8e-13 49.7 0.0 1.6 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KIK41963.1 - 0.0022 17.5 0.4 1.6 8.1 0.1 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain AAA PF00004.29 KIK41964.1 - 8e-54 181.6 0.0 3.9e-42 143.8 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KIK41964.1 - 7.4e-22 77.6 0.5 2.1e-21 76.1 0.5 1.9 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 KIK41964.1 - 1.3e-14 54.9 3.3 8e-07 29.6 0.3 4.9 2 2 1 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 KIK41964.1 - 8.8e-11 41.4 2.3 6.5e-09 35.5 0.2 2.8 3 0 0 3 3 2 1 AAA+ lid domain AAA_22 PF13401.6 KIK41964.1 - 4.5e-07 30.2 0.3 0.048 13.9 0.0 4.1 2 2 1 3 3 3 2 AAA domain RuvB_N PF05496.12 KIK41964.1 - 4.7e-07 29.7 0.0 0.0045 16.8 0.0 2.7 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KIK41964.1 - 6.3e-07 30.0 0.0 0.034 14.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KIK41964.1 - 6e-06 26.3 0.0 0.19 11.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) TsaE PF02367.17 KIK41964.1 - 2.7e-05 24.2 0.0 0.31 11.0 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KIK41964.1 - 4.2e-05 23.7 0.2 0.06 13.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 KIK41964.1 - 4.6e-05 23.5 0.0 0.43 10.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KIK41964.1 - 6.3e-05 23.3 0.0 0.61 10.5 0.0 2.5 2 0 0 2 2 2 2 RNA helicase TIP49 PF06068.13 KIK41964.1 - 8.5e-05 21.9 0.0 0.047 12.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain NACHT PF05729.12 KIK41964.1 - 0.00021 21.3 0.8 0.35 10.8 0.1 3.3 2 1 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 KIK41964.1 - 0.00025 20.3 0.0 0.21 10.7 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_2 PF07724.14 KIK41964.1 - 0.00033 20.8 0.0 1.2 9.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 KIK41964.1 - 0.00082 19.1 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.6 KIK41964.1 - 0.00083 19.0 0.0 0.48 10.0 0.0 3.3 2 1 1 3 3 3 1 AAA domain AAA_7 PF12775.7 KIK41964.1 - 0.00093 18.8 0.0 0.18 11.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 KIK41964.1 - 0.0016 18.2 0.0 0.55 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KIK41964.1 - 0.0016 18.2 0.0 0.46 10.2 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase_2 PF01637.18 KIK41964.1 - 0.0018 18.2 0.1 0.25 11.2 0.0 2.7 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 KIK41964.1 - 0.003 17.5 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain Zeta_toxin PF06414.12 KIK41964.1 - 0.0034 16.7 0.0 1.5 8.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_3 PF07726.11 KIK41964.1 - 0.0037 17.1 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KIK41964.1 - 0.0078 16.1 0.0 0.2 11.5 0.0 2.4 2 0 0 2 2 2 1 NTPase AAA_17 PF13207.6 KIK41964.1 - 0.0088 16.5 0.4 0.29 11.6 0.0 2.6 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.21 KIK41964.1 - 0.01 15.2 0.0 0.7 9.2 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KIK41964.1 - 0.012 15.9 0.0 7.2 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.10 KIK41964.1 - 0.012 15.6 0.1 0.035 14.1 0.1 1.8 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain SKI PF01202.22 KIK41964.1 - 0.021 14.9 0.0 1.9 8.6 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase TniB PF05621.11 KIK41964.1 - 0.026 13.9 0.0 1.6 8.1 0.0 2.9 2 1 1 3 3 3 0 Bacterial TniB protein Viral_helicase1 PF01443.18 KIK41964.1 - 0.032 14.0 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Hpr_kinase_C PF07475.12 KIK41964.1 - 0.034 13.7 0.1 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain DUF2075 PF09848.9 KIK41964.1 - 0.042 13.1 0.0 6.3 5.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 KIK41964.1 - 0.043 13.9 0.0 12 6.0 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 KIK41964.1 - 0.051 14.1 0.0 8.5 6.9 0.0 2.5 2 0 0 2 2 2 0 ABC transporter DUF815 PF05673.13 KIK41964.1 - 0.055 12.6 0.0 4 6.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.25 KIK41964.1 - 0.13 11.9 0.0 0.49 10.0 0.0 2.0 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Cytidylate_kin2 PF13189.6 KIK41964.1 - 0.16 12.1 0.0 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family ATPase PF06745.13 KIK41964.1 - 0.17 11.2 0.1 8.1 5.7 0.0 2.8 3 0 0 3 3 3 0 KaiC DUF3638 PF12340.8 KIK41970.1 - 8.7e-85 283.6 0.5 2e-84 282.4 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KIK41970.1 - 2.4e-17 62.0 0.1 5.9e-17 60.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) RhoGEF67_u2 PF16614.5 KIK41971.1 - 0.0016 18.5 0.0 0.0044 17.1 0.0 1.7 1 0 0 1 1 1 1 Unstructured region two on RhoGEF 6 and 7 Exo_endo_phos PF03372.23 KIK41971.1 - 0.018 14.5 0.1 0.023 14.2 0.1 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family PH PF00169.29 KIK41972.1 - 1e-08 35.6 0.0 0.00023 21.6 0.0 2.7 2 0 0 2 2 2 2 PH domain XPG_I PF00867.18 KIK41973.1 - 1.1e-25 89.8 0.0 4.7e-25 87.8 0.0 2.2 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KIK41973.1 - 2.2e-23 82.6 0.0 5.9e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KIK41973.1 - 0.0016 19.0 0.1 0.03 14.9 0.0 2.8 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.7 KIK41973.1 - 0.0037 16.8 0.0 0.0091 15.5 0.0 1.6 1 1 0 1 1 1 1 XPG domain containing NDUF_B8 PF05821.11 KIK41974.1 - 9.6e-06 25.6 2.6 2.1e-05 24.5 2.6 1.7 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Pex14_N PF04695.13 KIK41974.1 - 0.068 13.8 0.0 0.1 13.3 0.0 1.3 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Methyltransf_25 PF13649.6 KIK41975.1 - 1.2e-17 64.3 0.0 3e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK41975.1 - 3.1e-14 53.4 0.0 1.6e-13 51.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK41975.1 - 3.7e-12 46.4 0.0 6.3e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK41975.1 - 2.5e-08 33.5 0.0 3.9e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KIK41975.1 - 6.2e-07 30.1 0.0 1.3e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK41975.1 - 1.2e-06 28.4 0.0 2.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KIK41975.1 - 0.00019 20.8 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KIK41975.1 - 0.00065 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KIK41975.1 - 0.0015 18.6 0.0 0.0028 17.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 KIK41975.1 - 0.023 14.0 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 KIK41975.1 - 0.031 13.8 0.0 0.095 12.2 0.0 1.7 1 1 1 2 2 2 0 Putative methyltransferase MetW PF07021.12 KIK41975.1 - 0.047 13.3 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.13 KIK41975.1 - 0.18 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pribosyltran PF00156.27 KIK41976.1 - 9.8e-13 47.9 0.1 1.4e-12 47.4 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Peptidase_M24 PF00557.24 KIK41978.1 - 1.3e-16 61.0 0.1 1.7e-16 60.6 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Pcc1 PF09341.10 KIK41979.1 - 5.4e-25 87.3 0.5 6.3e-25 87.1 0.5 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 p450 PF00067.22 KIK41980.1 - 4.6e-56 190.5 0.0 6.1e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4791 PF16039.5 KIK41980.1 - 0.17 11.4 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4791) Kelch_4 PF13418.6 KIK41982.1 - 1.4e-20 73.0 3.8 0.002 18.1 0.0 6.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KIK41982.1 - 5.6e-16 58.2 6.1 5.6e-05 23.3 0.2 5.8 3 1 2 5 5 5 4 Kelch motif Kelch_5 PF13854.6 KIK41982.1 - 7.1e-16 57.8 1.3 1.2e-05 25.2 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KIK41982.1 - 5.1e-11 42.0 0.4 0.12 12.0 0.0 5.9 5 1 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 KIK41982.1 - 1.7e-06 27.7 0.3 0.17 11.9 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 KIK41982.1 - 2.3e-06 27.7 12.0 0.0098 16.2 0.4 5.7 5 0 0 5 5 5 2 Galactose oxidase, central domain Keratin PF02422.16 KIK41984.1 - 0.038 13.7 0.4 0.044 13.5 0.4 1.1 1 0 0 1 1 1 0 Keratin YycI PF09648.10 KIK41984.1 - 0.23 11.0 0.0 0.28 10.7 0.0 1.1 1 0 0 1 1 1 0 YycH protein ACBP PF00887.19 KIK41986.1 - 3e-24 85.1 1.4 3.6e-24 84.8 1.4 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein SF3A3 PF16837.5 KIK41986.1 - 0.085 13.4 0.3 0.13 12.8 0.3 1.5 1 1 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 PH PF00169.29 KIK41987.1 - 7.3e-34 116.4 0.8 1.3e-17 64.2 0.3 2.6 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KIK41987.1 - 5.5e-12 46.0 10.6 1.7e-05 25.2 2.9 4.0 2 2 1 3 3 3 3 Pleckstrin homology domain PH_8 PF15409.6 KIK41987.1 - 1.9e-07 31.3 2.4 8.4e-06 26.0 0.2 2.6 3 0 0 3 3 3 1 Pleckstrin homology domain PH_13 PF16652.5 KIK41987.1 - 0.00018 21.4 0.0 0.039 13.7 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH_2 PF08458.10 KIK41987.1 - 0.0031 17.8 0.0 3.7 8.0 0.0 2.4 2 0 0 2 2 2 2 Plant pleckstrin homology-like region PH_9 PF15410.6 KIK41987.1 - 0.031 14.6 2.2 0.99 9.8 0.7 3.2 2 2 0 2 2 2 0 Pleckstrin homology domain PH_4 PF15404.6 KIK41987.1 - 0.06 13.1 0.1 0.55 10.0 0.0 2.6 3 0 0 3 3 3 0 Pleckstrin homology domain Mcp5_PH PF12814.7 KIK41987.1 - 0.4 10.8 3.9 6.4 6.9 0.0 3.1 3 1 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology Sporozoite_P67 PF05642.11 KIK41987.1 - 5 5.1 18.5 0.32 9.0 3.1 3.1 3 0 0 3 3 3 0 Sporozoite P67 surface antigen Fungal_trans_2 PF11951.8 KIK41988.1 - 1e-40 139.8 8.1 3.2e-40 138.1 8.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK41988.1 - 0.00028 21.0 7.3 0.00061 19.9 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TcfC PF16967.5 KIK41991.1 - 0.0094 15.4 0.0 0.06 12.8 0.0 2.0 1 1 1 2 2 2 1 E-set like domain Fungal_trans_2 PF11951.8 KIK41992.1 - 5.7e-34 117.6 0.5 7.7e-34 117.1 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase_Tyr PF07714.17 KIK41993.1 - 5.5e-40 137.3 0.0 1.2e-39 136.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Fungal_trans_2 PF11951.8 KIK41993.1 - 1.1e-37 129.8 6.3 3e-37 128.4 6.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 KIK41993.1 - 3.9e-31 108.4 0.0 7.1e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIK41993.1 - 0.2 11.2 0.2 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 KIK41993.1 - 0.9 9.4 5.8 1.3 8.9 0.5 2.8 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KIK41995.1 - 2.8e-36 125.1 0.0 3.1e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK41995.1 - 3e-28 98.9 0.0 3.5e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK41995.1 - 0.013 15.4 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KIK41995.1 - 0.07 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DUF3295 PF11702.8 KIK41996.1 - 2.9e-11 43.4 5.8 2.9e-11 43.4 5.8 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3295) PBP1_TM PF14812.6 KIK41996.1 - 2.3 8.7 7.6 0.93 9.9 1.8 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fungal_trans_2 PF11951.8 KIK41997.1 - 0.018 13.9 0.1 0.03 13.1 0.1 1.3 1 1 0 1 1 1 0 Fungal specific transcription factor domain HTH_40 PF14493.6 KIK41997.1 - 0.054 14.0 0.0 0.086 13.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Pkinase_Tyr PF07714.17 KIK41998.1 - 6e-39 133.9 0.0 1.1e-38 133.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Fungal_trans_2 PF11951.8 KIK41998.1 - 1.1e-35 123.2 1.5 1.8e-35 122.5 1.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 KIK41998.1 - 8.7e-32 110.5 0.0 1.5e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Zn_clus PF00172.18 KIK41998.1 - 0.0048 17.0 5.9 0.011 15.8 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KIK41999.1 - 1.1e-44 152.8 0.9 1.6e-44 152.3 0.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK41999.1 - 8e-05 22.7 9.8 0.00013 22.0 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Drf_GBD PF06371.13 KIK42000.1 - 4.1e-16 59.1 0.4 1.4e-14 54.1 0.2 2.6 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain DUF4401 PF14351.6 KIK42001.1 - 0.44 9.8 16.4 0.072 12.4 12.7 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4401) DnaJ_C PF01556.18 KIK42003.1 - 7.4e-22 78.0 0.0 1.2e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIK42003.1 - 3e-16 59.3 0.0 6.4e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 KIK42005.1 - 5.9e-40 136.8 0.1 7.9e-40 136.3 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIK42005.1 - 4.6e-28 97.1 0.7 6.7e-28 96.6 0.7 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 KIK42005.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 A repeated domain in UCH-protein TIR_2 PF13676.6 KIK42006.1 - 0.027 15.1 0.0 0.05 14.2 0.0 1.5 1 0 0 1 1 1 0 TIR domain Methyltransf_11 PF08241.12 KIK42008.1 - 1e-12 48.5 0.0 2.1e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK42008.1 - 1.6e-09 38.3 0.0 4e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK42008.1 - 5.7e-05 23.0 0.0 8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK42008.1 - 7.9e-05 23.3 0.0 0.00014 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KIK42008.1 - 0.036 15.1 0.1 0.1 13.6 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain FAD_binding_3 PF01494.19 KIK42009.1 - 2.4e-17 63.2 0.0 2.1e-10 40.4 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KIK42009.1 - 0.0089 16.2 0.8 0.02 15.1 0.8 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK42009.1 - 0.039 13.6 0.0 0.082 12.5 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIK42009.1 - 0.065 13.8 0.4 5.7 7.6 0.3 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK42009.1 - 0.19 10.9 0.0 0.44 9.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MaoC_dehydratas PF01575.19 KIK42010.1 - 0.0017 17.9 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain Methyltransf_PK PF05891.12 KIK42011.1 - 2.1e-58 197.4 0.0 1.4e-57 194.7 0.0 2.1 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KIK42011.1 - 5.1e-07 30.3 0.0 0.046 14.4 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KIK42011.1 - 5.1e-06 26.4 0.0 1.8e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK42011.1 - 1.4e-05 25.6 0.0 0.0032 18.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK42011.1 - 3.2e-05 24.6 0.0 0.48 11.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_2 PF00891.18 KIK42011.1 - 0.13 11.5 0.0 0.34 10.2 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase domain Swi3 PF07962.12 KIK42012.1 - 2.5e-29 101.1 0.1 3.7e-29 100.5 0.1 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 WD40 PF00400.32 KIK42015.1 - 0.0018 19.1 9.6 0.0093 16.8 0.5 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat Gemini_BL1 PF00845.19 KIK42015.1 - 0.073 12.7 0.2 0.55 9.8 0.2 2.0 2 0 0 2 2 2 0 Geminivirus BL1 movement protein PRIMA1 PF16101.5 KIK42016.1 - 4.5 7.3 6.5 11 6.1 6.5 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SAP PF02037.27 KIK42017.1 - 3.5e-08 33.0 0.0 5.7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 SAP domain Histone PF00125.24 KIK42018.1 - 7.4e-22 78.1 1.3 9.1e-22 77.8 1.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 KIK42018.1 - 0.00011 22.7 0.0 0.00021 21.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KIK42018.1 - 0.00031 21.0 0.0 0.00066 19.9 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 KIK42018.1 - 0.015 15.3 0.1 0.018 15.1 0.1 1.1 1 0 0 1 1 1 0 YscO-like protein Bt_P21 PF05560.11 KIK42018.1 - 0.035 13.7 0.0 0.043 13.4 0.0 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein ORC6 PF05460.13 KIK42018.1 - 0.08 12.2 2.6 0.091 12.0 2.6 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PRCC PF10253.9 KIK42019.1 - 2.7e-29 103.5 19.8 4.1e-29 102.9 13.4 2.7 2 1 0 2 2 2 2 Mitotic checkpoint regulator, MAD2B-interacting Nucleoporin_C PF03177.14 KIK42020.1 - 4.3e-54 184.3 0.0 8.9e-54 183.2 0.0 1.5 2 0 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KIK42020.1 - 8.1e-14 51.2 0.0 1.2e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like DUF2315 PF10231.9 KIK42021.1 - 4.7e-25 88.1 0.8 7.2e-25 87.5 0.8 1.3 1 0 0 1 1 1 1 Apoptogenic protein 1 ADK PF00406.22 KIK42022.1 - 7.6e-44 149.5 0.0 1e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KIK42022.1 - 4.6e-20 72.4 0.0 1.1e-19 71.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KIK42022.1 - 7e-14 51.5 0.0 1.1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KIK42022.1 - 4.6e-07 30.4 0.0 8.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIK42022.1 - 0.00011 22.4 0.0 0.00036 20.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 KIK42022.1 - 0.051 13.5 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Hydin_ADK PF17213.3 KIK42022.1 - 0.057 13.7 0.1 0.4 11.0 0.0 2.2 2 1 1 3 3 3 0 Hydin Adenylate kinase-like domain DNA_ligase_A_M PF01068.21 KIK42022.1 - 0.11 12.1 0.0 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 ATP dependent DNA ligase domain Epimerase PF01370.21 KIK42024.1 - 3.1e-11 43.2 0.0 2.3e-08 33.8 0.0 2.4 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK42024.1 - 1.4e-08 34.8 0.0 4.5e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIK42024.1 - 4.3e-05 22.7 0.0 0.0015 17.6 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIK42024.1 - 0.0029 17.1 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KIK42024.1 - 0.02 14.0 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 KIK42024.1 - 0.022 14.2 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.12 KIK42024.1 - 0.085 12.0 0.2 0.62 9.2 0.0 2.4 3 0 0 3 3 3 0 Male sterility protein DFP PF04127.15 KIK42024.1 - 0.085 12.7 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 2-Hacid_dh_C PF02826.19 KIK42024.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 KIK42024.1 - 0.19 11.4 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DPBB_1 PF03330.18 KIK42025.1 - 4.2e-08 33.4 0.4 4.2e-08 33.4 0.4 2.5 2 2 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 KIK42025.1 - 7e-05 22.7 2.2 0.00013 21.8 1.3 1.9 1 1 0 1 1 1 1 Barwin family PRCC PF10253.9 KIK42025.1 - 0.055 14.2 4.7 0.075 13.8 4.7 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SOG2 PF10428.9 KIK42025.1 - 0.11 11.7 9.9 0.11 11.7 9.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 KIK42025.1 - 1.5 7.4 9.9 1.8 7.1 9.9 1.1 1 0 0 1 1 1 0 Hamartin protein SCAMP PF04144.13 KIK42026.1 - 2e-56 191.0 8.8 2.3e-56 190.8 8.8 1.0 1 0 0 1 1 1 1 SCAMP family Melibiase_C PF17801.1 KIK42026.1 - 0.005 16.9 0.1 0.0083 16.2 0.1 1.3 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain CRCB PF02537.15 KIK42026.1 - 1.2 9.5 6.4 2.8 8.3 6.4 1.6 1 1 0 1 1 1 0 CrcB-like protein, Camphor Resistance (CrcB) RRM_1 PF00076.22 KIK42027.1 - 6.3e-83 272.6 4.3 3.1e-21 75.0 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KIK42027.1 - 5.7e-26 90.5 1.4 1.9e-25 88.8 1.4 2.0 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_7 PF16367.5 KIK42027.1 - 3.3e-05 23.9 0.3 5.6 7.2 0.0 4.8 4 2 0 4 4 4 2 RNA recognition motif RRM_3 PF08777.11 KIK42027.1 - 0.00011 22.1 6.9 0.078 13.0 1.6 3.9 4 0 0 4 4 4 1 RNA binding motif Nup35_RRM_2 PF14605.6 KIK42027.1 - 0.00019 21.4 0.6 3 7.9 0.0 4.1 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 KIK42027.1 - 0.00053 19.6 0.9 2.6 7.8 0.0 3.4 3 0 0 3 3 3 2 Ribonuclease B OB domain DUF4407 PF14362.6 KIK42027.1 - 0.007 15.7 2.2 0.02 14.3 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) Limkain-b1 PF11608.8 KIK42027.1 - 0.03 14.4 1.3 3.2 7.9 0.1 3.3 3 0 0 3 3 3 0 Limkain b1 YflT PF11181.8 KIK42027.1 - 0.062 13.8 4.3 1.4 9.5 0.5 2.8 3 0 0 3 3 3 0 Heat induced stress protein YflT CSD PF00313.22 KIK42027.1 - 0.14 12.0 1.5 22 5.0 0.1 3.3 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain Erf4 PF10256.9 KIK42027.1 - 0.14 12.2 0.9 7.7 6.7 0.1 3.2 3 1 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family PNPase PF03726.14 KIK42027.1 - 0.36 11.3 2.1 0.53 10.8 0.1 2.2 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Nefa_Nip30_N PF10187.9 KIK42027.1 - 0.61 10.5 6.0 0.29 11.5 0.2 2.5 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Methyltransf_25 PF13649.6 KIK42028.1 - 1.1e-15 58.1 0.0 2.4e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK42028.1 - 1.3e-15 57.6 0.0 1.8e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK42028.1 - 5.1e-14 52.7 0.0 9.3e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK42028.1 - 4.1e-12 46.2 0.0 3.3e-11 43.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK42028.1 - 1.3e-07 32.3 0.0 8.1e-07 29.7 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_29 PF03141.16 KIK42028.1 - 1.3e-06 27.3 0.0 2.1e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 KIK42028.1 - 4.1e-05 23.0 0.0 0.00012 21.5 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KIK42028.1 - 0.00024 20.6 0.0 0.018 14.5 0.0 2.2 1 1 1 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.15 KIK42028.1 - 0.002 18.0 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 KIK42028.1 - 0.0026 17.1 0.0 0.0069 15.7 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KIK42028.1 - 0.0032 16.8 0.0 0.0084 15.4 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase domain PrmA PF06325.13 KIK42028.1 - 0.0046 16.4 0.0 0.0088 15.5 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KIK42028.1 - 0.028 14.0 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain FtsJ PF01728.19 KIK42028.1 - 0.059 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase GidB PF02527.15 KIK42028.1 - 0.18 11.1 0.0 0.44 9.8 0.1 1.5 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G WD40 PF00400.32 KIK42029.1 - 4.4e-10 40.0 20.0 0.11 13.4 0.0 7.8 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42029.1 - 0.024 14.9 0.0 21 5.5 0.0 3.3 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIF_alpha PF05793.12 KIK42029.1 - 0.29 9.7 5.9 0.44 9.1 5.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 KIK42029.1 - 2.9 6.0 6.4 3.7 5.6 6.4 1.1 1 0 0 1 1 1 0 Nop14-like family SRP54 PF00448.22 KIK42030.1 - 1.4e-72 243.4 0.9 2.4e-72 242.7 0.9 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KIK42030.1 - 6.8e-30 103.6 1.2 6.8e-30 103.6 1.2 3.7 3 1 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 KIK42030.1 - 1.2e-18 67.1 4.0 2.8e-18 65.9 4.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 KIK42030.1 - 0.00064 19.9 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KIK42030.1 - 0.0025 17.9 0.0 0.0085 16.1 0.0 2.0 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 KIK42030.1 - 0.0079 15.5 0.1 0.015 14.6 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 KIK42030.1 - 0.028 14.9 0.1 0.028 14.9 0.1 2.5 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KIK42030.1 - 0.061 13.0 3.0 0.067 12.9 0.1 2.5 3 0 0 3 3 3 0 AAA domain 6PF2K PF01591.18 KIK42030.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase HTH_ParB PF17762.1 KIK42030.1 - 0.15 11.9 1.7 3 7.7 0.3 2.7 2 0 0 2 2 2 0 HTH domain found in ParB protein His_Phos_2 PF00328.22 KIK42032.1 - 6e-31 108.1 0.0 8.6e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.22 KIK42033.1 - 4.5e-17 62.5 0.0 5.6e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SH2_2 PF14633.6 KIK42034.1 - 5.9e-73 244.8 0.2 5.9e-73 244.8 0.2 2.1 3 0 0 3 3 3 1 SH2 domain HHH_7 PF14635.6 KIK42034.1 - 8.6e-30 103.2 0.0 1.8e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KIK42034.1 - 4.5e-27 94.7 0.1 2.4e-16 59.8 0.1 2.6 2 0 0 2 2 2 2 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 KIK42034.1 - 5e-27 94.6 0.1 1.3e-26 93.3 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 KIK42034.1 - 3.1e-21 75.7 26.6 3.1e-21 75.7 26.6 5.3 4 1 1 5 5 5 1 Acidic N-terminal SPT6 SH2 PF00017.24 KIK42034.1 - 4.6e-07 29.8 0.0 6.2e-06 26.2 0.0 2.6 2 0 0 2 2 2 1 SH2 domain HHH_9 PF17674.1 KIK42034.1 - 1.5e-06 29.0 2.1 1.3e-05 26.0 2.1 2.7 1 1 0 1 1 1 1 HHH domain HHH_3 PF12836.7 KIK42034.1 - 0.00077 19.7 0.0 0.0026 18.0 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif S1 PF00575.23 KIK42034.1 - 0.013 15.8 0.6 0.033 14.5 0.6 1.6 1 0 0 1 1 1 0 S1 RNA binding domain Inv-AAD PF18785.1 KIK42035.1 - 2.6e-23 82.3 0.0 3.7e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KIK42035.1 - 5.7e-10 39.0 0.0 1e-09 38.2 0.0 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KIK42035.1 - 0.015 15.0 2.3 0.037 13.8 0.1 2.4 2 1 0 2 2 2 0 MafB19-like deaminase Condensation PF00668.20 KIK42036.1 - 2.2e-98 329.9 0.1 3.6e-38 131.4 0.0 3.5 3 1 0 3 3 3 3 Condensation domain AMP-binding PF00501.28 KIK42036.1 - 3.9e-86 289.3 0.0 5.6e-86 288.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KIK42036.1 - 7.3e-32 109.5 1.1 2.3e-10 40.7 0.1 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KIK42036.1 - 0.01 16.8 0.0 0.055 14.5 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 KIK42036.1 - 0.16 10.8 0.0 1 8.1 0.0 2.0 2 0 0 2 2 2 0 GH3 auxin-responsive promoter CDC45 PF02724.14 KIK42038.1 - 8.6e-05 21.0 5.2 8.6e-05 21.0 5.2 1.0 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 KIK42038.1 - 0.56 8.4 18.6 0.68 8.1 18.6 1.0 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 KIK42038.1 - 4.2 5.8 10.5 4.4 5.7 10.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pkinase_fungal PF17667.1 KIK42039.1 - 4.8e-18 65.1 0.0 5.9e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase p450 PF00067.22 KIK42040.1 - 7.7e-67 226.0 0.0 9.5e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fra10Ac1 PF09725.9 KIK42041.1 - 9.1e-49 164.7 0.7 1.3e-48 164.2 0.7 1.2 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 DUF2039 PF10217.9 KIK42041.1 - 0.012 15.9 0.4 0.031 14.6 0.4 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) RNA_pol_Rpc4 PF05132.14 KIK42041.1 - 0.19 12.1 2.4 0.99 9.8 0.0 2.2 1 1 1 2 2 2 0 RNA polymerase III RPC4 CDC45 PF02724.14 KIK42041.1 - 1.4 7.1 7.6 1.6 6.9 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SRRM_C PF15230.6 KIK42041.1 - 4.8 7.8 19.7 1.6 9.3 16.4 1.8 1 1 1 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus p450 PF00067.22 KIK42042.1 - 1e-61 209.1 0.0 3.3e-61 207.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Phage_holin_1 PF04531.13 KIK42043.1 - 0.57 10.8 3.0 11 6.6 0.7 2.6 2 0 0 2 2 2 0 Bacteriophage holin DUF3328 PF11807.8 KIK42044.1 - 5e-17 62.4 9.7 7.1e-17 61.9 4.4 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3328) TDP43_N PF18694.1 KIK42045.1 - 0.049 13.5 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Transactive response DNA-binding protein N-terminal domain Imm27 PF15590.6 KIK42049.1 - 0.035 13.9 11.6 5.8 6.8 0.1 4.5 1 1 4 5 5 5 0 Immunity protein 27 Hamartin PF04388.12 KIK42050.1 - 1.2 7.7 5.4 1.4 7.5 5.4 1.0 1 0 0 1 1 1 0 Hamartin protein Citrate_synt PF00285.21 KIK42051.1 - 5.2e-119 397.5 0.0 6.5e-119 397.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain GST_N_3 PF13417.6 KIK42052.1 - 4.1e-17 62.4 0.0 7.5e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK42052.1 - 2.7e-15 56.5 0.0 4.9e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK42052.1 - 3.1e-10 40.1 0.0 4.4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KIK42052.1 - 1.3e-08 35.0 0.0 2.4e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIK42052.1 - 3.6e-05 23.9 0.0 7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK42052.1 - 0.00015 21.7 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KIK42052.1 - 0.015 15.1 0.0 0.041 13.7 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KIK42052.1 - 0.12 13.2 0.0 0.19 12.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Zn_clus PF00172.18 KIK42053.1 - 1.1e-07 31.9 12.8 1.1e-07 31.9 12.8 1.5 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KIK42059.1 - 8.3e-74 249.0 0.0 9.9e-74 248.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RNB PF00773.19 KIK42060.1 - 3.4e-51 174.5 0.0 8.5e-51 173.2 0.0 1.6 1 1 0 1 1 1 1 RNB domain Pkinase PF00069.25 KIK42062.1 - 3.2e-42 144.7 0.0 3.3e-24 85.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK42062.1 - 9.2e-19 67.7 0.0 2.2e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIK42062.1 - 2.4e-05 23.8 0.0 0.019 14.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KIK42062.1 - 0.0088 16.0 0.0 0.26 11.2 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family DDDD PF10161.9 KIK42065.1 - 0.19 11.5 0.1 5.8 6.7 0.0 2.1 2 0 0 2 2 2 0 Putative mitochondrial precursor protein Vps51 PF08700.11 KIK42067.1 - 1.6e-23 82.5 0.6 2.6e-23 81.9 0.6 1.3 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 KIK42067.1 - 0.041 14.1 0.9 0.063 13.4 0.9 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Dor1 PF04124.12 KIK42067.1 - 0.054 12.2 0.6 0.07 11.8 0.6 1.1 1 0 0 1 1 1 0 Dor1-like family FlgN PF05130.12 KIK42067.1 - 0.057 13.9 0.6 0.084 13.4 0.6 1.2 1 0 0 1 1 1 0 FlgN protein ATP_synt_H PF05493.13 KIK42068.1 - 1.6e-22 79.7 6.1 2e-22 79.4 6.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.6 KIK42068.1 - 0.042 13.5 1.2 0.047 13.4 1.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Ndc1_Nup PF09531.10 KIK42068.1 - 0.06 12.0 1.3 0.06 12.0 1.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LPAM_2 PF13627.6 KIK42068.1 - 1.9 8.5 6.8 0.78 9.7 0.5 2.4 2 0 0 2 2 2 0 Prokaryotic lipoprotein-attachment site Fig1 PF12351.8 KIK42068.1 - 3 7.7 6.4 3.2 7.6 6.4 1.0 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Pkinase_fungal PF17667.1 KIK42069.1 - 4.8e-24 84.9 0.0 3.5e-20 72.2 0.0 2.3 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIK42069.1 - 0.003 17.0 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ATP_synt_H PF05493.13 KIK42073.1 - 8.4e-19 67.8 8.4 9.6e-19 67.6 8.4 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.6 KIK42073.1 - 0.09 12.4 2.7 0.097 12.3 2.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Spore_YhaL PF14147.6 KIK42073.1 - 0.18 11.5 0.8 0.25 11.1 0.1 1.6 1 1 1 2 2 2 0 Sporulation protein YhaL LPAM_2 PF13627.6 KIK42073.1 - 2.4 8.1 7.4 0.72 9.8 0.7 2.2 2 0 0 2 2 2 0 Prokaryotic lipoprotein-attachment site Tau95_N PF17682.1 KIK42074.1 - 0.047 13.9 0.0 0.055 13.7 0.0 1.1 1 0 0 1 1 1 0 Tau95 Triple barrel domain FAD_binding_3 PF01494.19 KIK42075.1 - 4.8e-48 164.2 0.0 1.3e-38 133.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KIK42075.1 - 0.00087 19.5 0.1 0.0028 17.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIK42075.1 - 0.084 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK42075.1 - 0.088 11.9 0.2 0.13 11.3 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KIK42075.1 - 0.12 11.6 0.1 0.21 10.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family G-alpha PF00503.20 KIK42078.1 - 1.3e-123 412.7 0.0 1.5e-123 412.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK42078.1 - 1.7e-13 50.4 0.1 7e-10 38.6 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KIK42078.1 - 0.00021 21.5 0.1 0.5 10.6 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KIK42078.1 - 0.00039 20.0 0.0 0.042 13.4 0.0 2.4 2 0 0 2 2 2 1 Ras family AAA_24 PF13479.6 KIK42078.1 - 0.012 15.3 0.0 0.54 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KIK42078.1 - 0.015 14.7 0.1 0.079 12.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein Gtr1_RagA PF04670.12 KIK42078.1 - 0.03 13.7 0.1 1.6 8.0 0.0 2.4 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 KIK42078.1 - 0.031 14.0 0.0 0.083 12.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRA1 PF07304.11 KIK42078.1 - 0.3 10.9 0.1 0.3 10.9 0.1 2.3 3 0 0 3 3 3 0 Steroid receptor RNA activator (SRA1) Pro_isomerase PF00160.21 KIK42079.1 - 6.8e-48 162.9 0.0 7.8e-48 162.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD F_actin_cap_B PF01115.17 KIK42080.1 - 2.8e-109 364.3 0.0 3.3e-109 364.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit CDC45 PF02724.14 KIK42082.1 - 0.00051 18.5 10.1 0.00051 18.5 10.1 1.1 1 0 0 1 1 1 1 CDC45-like protein AAA_16 PF13191.6 KIK42083.1 - 1.3e-09 38.7 0.1 7.4e-09 36.2 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain ATPase_2 PF01637.18 KIK42083.1 - 9.8e-06 25.6 0.0 2.8e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NACHT PF05729.12 KIK42083.1 - 5.1e-05 23.3 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 KIK42083.1 - 0.00091 19.7 0.0 0.0031 17.9 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KIK42083.1 - 0.002 18.0 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase PhoU PF01895.19 KIK42083.1 - 0.011 16.1 1.8 0.16 12.4 0.1 2.9 3 0 0 3 3 3 0 PhoU domain RNA_helicase PF00910.22 KIK42083.1 - 0.02 15.3 0.0 0.049 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 KIK42083.1 - 0.034 13.2 0.0 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 KIK42083.1 - 0.05 12.8 0.0 0.12 11.5 0.0 1.8 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 KIK42083.1 - 0.16 12.5 0.0 0.74 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KIK42085.1 - 0.16 11.8 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 Adenylylsulphate kinase CtIP_N PF10482.9 KIK42086.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Flavin_Reduct PF01613.18 KIK42087.1 - 2.1e-15 57.1 0.0 2.9e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain HET PF06985.11 KIK42088.1 - 3.9e-13 50.0 3.1 1.7e-10 41.4 0.2 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) WD40 PF00400.32 KIK42090.1 - 3.9e-34 116.1 22.8 6.1e-05 23.7 0.6 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42090.1 - 4.8e-12 46.0 3.0 0.027 14.8 0.1 5.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK42090.1 - 3.1e-10 40.3 0.1 0.0086 16.0 0.0 3.2 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK42090.1 - 0.0069 16.3 0.0 3.2 7.8 0.0 4.0 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK42090.1 - 0.04 12.9 3.9 5.5 5.8 0.3 4.1 1 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK42090.1 - 1.9 7.1 6.4 6.1 5.4 0.2 3.1 3 1 1 4 4 4 0 Nucleoporin Nup120/160 HET PF06985.11 KIK42091.1 - 9.1e-12 45.6 2.2 4.1e-11 43.4 0.2 2.5 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF5588 PF17826.1 KIK42092.1 - 0.0021 17.0 0.1 0.0021 17.0 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5588) WD40 PF00400.32 KIK42093.1 - 4e-20 71.8 13.6 0.00015 22.5 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42093.1 - 2e-06 28.0 0.8 6.1 7.2 0.0 4.8 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK42094.1 - 4.5e-45 150.7 10.9 1.4e-08 35.3 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42094.1 - 1.1e-13 51.3 0.3 0.0025 18.1 0.0 5.5 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK42094.1 - 2.7e-09 37.2 0.1 0.043 13.7 0.0 3.1 2 1 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK42094.1 - 0.00017 20.6 2.9 0.028 13.4 0.1 3.6 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KIK42094.1 - 0.0016 17.0 1.3 0.057 11.9 0.0 2.7 2 1 1 3 3 3 1 Cytochrome D1 heme domain PQQ_3 PF13570.6 KIK42094.1 - 0.011 16.1 4.3 8.3 7.0 0.0 5.5 5 2 1 6 6 6 0 PQQ-like domain Nup160 PF11715.8 KIK42094.1 - 0.048 12.3 3.6 2.5 6.6 0.0 3.3 1 1 3 4 4 4 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK42094.1 - 0.055 12.8 0.0 5 6.4 0.0 3.0 3 0 0 3 3 3 0 WD40-like domain F_bP_aldolase PF01116.20 KIK42098.1 - 6.1e-95 317.9 0.0 6.8e-95 317.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Lipase_GDSL_2 PF13472.6 KIK42098.1 - 0.028 14.8 0.1 0.054 13.9 0.1 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Torsin PF06309.11 KIK42098.1 - 0.11 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Torsin Cu-oxidase PF00394.22 KIK42099.1 - 2.8e-44 151.0 0.1 4.8e-41 140.5 0.0 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK42099.1 - 1.7e-37 128.2 3.9 2.3e-35 121.3 0.2 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK42099.1 - 2.6e-37 127.4 0.9 6.5e-37 126.2 0.2 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KIK42100.1 - 1.7e-45 155.0 0.0 3.8e-41 140.8 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK42100.1 - 1.6e-38 131.5 3.3 3.3e-37 127.3 0.1 3.3 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK42100.1 - 1.1e-35 122.2 0.3 6.6e-35 119.7 0.1 2.4 3 0 0 3 3 3 1 Multicopper oxidase ABC_membrane PF00664.23 KIK42102.1 - 3.7e-70 236.7 30.9 9.4e-38 130.4 12.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK42102.1 - 5.7e-53 179.1 0.0 2.3e-31 109.1 0.0 2.9 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KIK42102.1 - 4.5e-07 29.5 2.5 0.3 10.5 0.0 4.2 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIK42102.1 - 4.2e-06 27.2 0.8 0.022 15.1 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KIK42102.1 - 5e-06 26.6 0.3 0.13 12.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KIK42102.1 - 2.1e-05 24.2 0.9 0.082 12.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF4574 PF15141.6 KIK42102.1 - 6.2e-05 22.8 0.0 0.00017 21.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 RsgA_GTPase PF03193.16 KIK42102.1 - 0.00035 20.5 0.6 0.41 10.5 0.2 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KIK42102.1 - 0.0036 17.2 5.0 3.4 7.4 0.1 3.7 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KIK42102.1 - 0.013 15.2 0.1 2.4 7.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 KIK42102.1 - 0.014 15.9 1.4 1.3 9.4 0.3 2.4 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KIK42102.1 - 0.015 15.4 2.8 0.95 9.5 0.8 2.4 2 0 0 2 2 2 0 Dynamin family MeaB PF03308.16 KIK42102.1 - 0.037 13.0 0.1 2.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 KIK42102.1 - 0.048 13.8 4.3 3.6 7.6 0.1 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_22 PF13401.6 KIK42102.1 - 0.051 13.9 2.0 1.8 8.8 0.1 3.6 2 1 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 KIK42102.1 - 0.059 12.2 0.6 0.17 10.6 0.0 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class T2SSE PF00437.20 KIK42102.1 - 0.067 12.2 0.0 8.6 5.3 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.19 KIK42102.1 - 0.09 12.4 0.3 2.8 7.5 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 KIK42102.1 - 0.13 11.5 0.1 15 4.8 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin 60KD_IMP PF02096.20 KIK42102.1 - 0.28 11.1 9.0 0.052 13.4 4.4 2.1 2 0 0 2 2 2 0 60Kd inner membrane protein NB-ARC PF00931.22 KIK42102.1 - 0.41 9.8 1.5 7.4 5.7 0.6 3.0 2 1 0 2 2 2 0 NB-ARC domain AIRC PF00731.20 KIK42103.1 - 1.2e-60 203.4 1.6 2.9e-60 202.1 0.3 2.3 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 KIK42103.1 - 7.1e-59 198.2 0.0 1e-58 197.7 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KIK42103.1 - 3e-19 68.4 0.0 6.6e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 KIK42103.1 - 0.00047 19.7 0.0 0.00084 18.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 KIK42103.1 - 0.0068 16.0 0.0 0.031 13.8 0.0 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KIK42103.1 - 0.024 14.7 0.1 0.078 13.0 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain Rsa3 PF14615.6 KIK42104.1 - 3.7e-17 61.6 0.0 6.3e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 Ribosome-assembly protein 3 RA PF00788.23 KIK42105.1 - 7.4e-11 42.5 0.6 1.5e-07 31.9 0.0 4.1 5 0 0 5 5 5 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 KIK42105.1 - 1.8e-05 24.2 0.0 3.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK42105.1 - 0.0016 18.3 0.1 0.007 16.2 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain WD40 PF00400.32 KIK42108.1 - 2.4e-07 31.3 0.1 0.024 15.5 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Di19_C PF14571.6 KIK42108.1 - 0.098 13.2 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal Asp PF00026.23 KIK42110.1 - 8.8e-18 64.8 0.0 1.4e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TetR_C_29 PF17938.1 KIK42111.1 - 0.052 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain CLP1_P PF16575.5 KIK42112.1 - 7.6e-34 117.1 0.0 1.9e-33 115.9 0.0 1.7 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 KIK42112.1 - 0.003 17.6 0.0 0.007 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIK42112.1 - 0.053 13.4 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2550 PF10739.9 KIK42114.1 - 0.033 14.2 0.1 0.042 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2550) Cyclin_N PF00134.23 KIK42115.1 - 1.4e-08 34.5 0.0 1.6e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KIK42115.1 - 0.0029 18.0 0.0 0.0076 16.6 0.0 1.9 1 1 0 1 1 1 1 Cyclin C-terminal domain Pkinase PF00069.25 KIK42116.1 - 1.6e-66 224.4 0.0 2e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK42116.1 - 4.9e-29 101.4 0.0 6.6e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 KIK42116.1 - 0.015 16.2 0.0 0.041 14.8 0.0 1.8 1 0 0 1 1 1 0 WD domain, G-beta repeat Haspin_kinase PF12330.8 KIK42116.1 - 0.033 13.1 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KIK42116.1 - 0.051 13.5 0.2 0.19 11.6 0.1 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KIK42116.1 - 0.092 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BcrAD_BadFG PF01869.20 KIK42119.1 - 3.1e-12 46.6 0.0 1.3e-11 44.6 0.0 2.1 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family PseudoU_synth_1 PF01416.20 KIK42121.1 - 4.9e-26 91.3 0.0 2.4e-24 85.9 0.0 2.8 2 1 0 2 2 2 1 tRNA pseudouridine synthase zf-H2C2_2 PF13465.6 KIK42122.1 - 0.065 13.7 0.2 0.065 13.7 0.2 3.2 4 0 0 4 4 4 0 Zinc-finger double domain Sel1 PF08238.12 KIK42124.1 - 4e-21 75.0 42.8 1.3e-05 25.7 1.5 9.4 9 1 0 9 9 9 6 Sel1 repeat TPR_2 PF07719.17 KIK42124.1 - 0.0031 17.5 0.7 0.0031 17.5 0.7 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK42124.1 - 0.027 15.3 1.0 0.73 10.8 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK42124.1 - 0.029 14.2 0.6 0.029 14.2 0.6 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIK42124.1 - 0.041 14.2 3.7 0.36 11.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK42124.1 - 0.73 10.5 16.9 0.72 10.6 0.2 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat SWIB PF02201.18 KIK42125.1 - 8.5e-27 92.9 0.0 1.4e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 KIK42125.1 - 0.016 15.1 0.1 0.069 13.1 0.1 2.1 2 1 0 2 2 2 0 DEK C terminal domain Macoilin PF09726.9 KIK42125.1 - 0.16 10.5 8.8 0.19 10.3 8.8 1.0 1 0 0 1 1 1 0 Macoilin family DUF572 PF04502.13 KIK42125.1 - 0.37 10.4 16.2 0.49 10.0 16.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) V_ATPase_I PF01496.19 KIK42125.1 - 0.97 7.3 5.1 1.5 6.6 5.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SRP-alpha_N PF04086.13 KIK42125.1 - 3.8 7.3 21.9 5.2 6.9 21.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 KIK42125.1 - 4 6.1 11.4 6.7 5.4 11.4 1.4 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 KIK42125.1 - 6.3 3.8 9.0 7.7 3.5 9.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 KIK42125.1 - 6.5 5.7 7.4 10 5.0 7.4 1.4 1 0 0 1 1 1 0 Solute carrier family 12 Ank_4 PF13637.6 KIK42126.1 - 0.00018 22.0 0.6 0.79 10.4 0.0 4.8 4 1 2 6 6 6 1 Ankyrin repeats (many copies) F-box-like PF12937.7 KIK42126.1 - 0.032 14.1 0.0 0.085 12.8 0.0 1.7 1 0 0 1 1 1 0 F-box-like Dimer_Tnp_hAT PF05699.14 KIK42126.1 - 5.9 6.7 15.5 14 5.5 0.0 5.5 6 1 1 7 7 7 0 hAT family C-terminal dimerisation region 2-Hacid_dh_C PF02826.19 KIK42131.1 - 2.3e-50 170.4 0.0 3e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIK42131.1 - 3.5e-14 52.6 0.0 4.9e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIK42131.1 - 0.00028 21.1 0.0 0.00051 20.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_17 PF12692.7 KIK42131.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase Glyco_transf_49 PF13896.6 KIK42132.1 - 6.5e-68 229.5 4.0 1.1e-55 189.3 0.2 2.0 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan YcaO PF02624.16 KIK42132.1 - 0.029 13.6 0.1 0.046 13.0 0.1 1.2 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding PPTA PF01239.22 KIK42133.1 - 9.3e-09 34.7 17.6 1.5e-05 24.6 0.1 5.4 6 0 0 6 6 6 3 Protein prenyltransferase alpha subunit repeat Cu-oxidase PF00394.22 KIK42134.1 - 1.4e-12 48.0 0.0 1.5e-12 47.9 0.0 1.0 1 0 0 1 1 1 1 Multicopper oxidase F-box-like PF12937.7 KIK42135.1 - 1.7e-07 31.0 1.2 4.1e-07 29.8 1.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK42135.1 - 0.00014 21.7 0.8 0.00031 20.5 0.8 1.6 1 0 0 1 1 1 1 F-box domain Fer4_11 PF13247.6 KIK42135.1 - 0.24 11.6 1.5 21 5.3 0.5 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain WD40 PF00400.32 KIK42136.1 - 8.5e-41 137.2 21.3 2.2e-07 31.5 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42136.1 - 3.9e-16 59.1 0.0 0.0037 17.5 0.1 5.4 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK42136.1 - 0.00046 19.3 0.3 1.6 7.6 0.0 3.7 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK42136.1 - 0.0014 18.6 0.0 0.72 9.7 0.0 2.5 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK42136.1 - 0.0017 17.8 0.0 0.48 9.7 0.0 3.2 2 1 1 3 3 3 2 WD40-like domain Cytochrom_D1 PF02239.16 KIK42136.1 - 0.14 10.7 0.0 0.22 10.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain RicinB_lectin_2 PF14200.6 KIK42137.1 - 1.8e-13 51.0 1.2 2e-09 38.0 0.6 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIK42137.1 - 3.1e-07 30.7 0.2 8.3e-06 26.1 0.2 2.1 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain SelP_N PF04592.14 KIK42139.1 - 0.13 11.7 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FGE-sulfatase PF03781.16 KIK42142.1 - 3.1e-17 63.0 1.5 2e-08 34.2 0.1 2.7 3 0 0 3 3 3 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KIK42142.1 - 1.3e-08 35.4 1.5 2.7e-08 34.4 1.5 1.6 1 0 0 1 1 1 1 DinB superfamily Condensation PF00668.20 KIK42144.1 - 7.8e-06 24.8 0.1 0.11 11.2 0.0 3.0 3 0 0 3 3 3 3 Condensation domain ATG7_N PF16420.5 KIK42145.1 - 2.3e-84 283.6 0.0 3e-84 283.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KIK42145.1 - 1.9e-46 158.4 0.0 2.7e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 ThiF family PSA_CBD PF18341.1 KIK42145.1 - 0.073 13.1 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 PSA endolysin C-terminal cell wall binding domain Proteasome PF00227.26 KIK42146.1 - 2e-46 157.9 0.1 2.6e-46 157.5 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KIK42146.1 - 1.4e-12 46.8 0.1 1.4e-12 46.8 0.1 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal NAD_Gly3P_dh_C PF07479.14 KIK42146.1 - 0.097 13.0 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus BAR_2 PF10455.9 KIK42147.1 - 1.6e-50 171.9 2.1 4.4e-50 170.5 2.1 1.6 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KIK42147.1 - 7.1e-15 55.3 3.8 8.3e-14 51.8 3.8 2.0 1 1 0 1 1 1 1 BAR domain PhoLip_ATPase_C PF16212.5 KIK42149.1 - 1.1e-80 271.0 26.4 1.1e-80 271.0 26.4 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KIK42149.1 - 1.7e-25 88.5 5.1 5.6e-25 86.8 5.1 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KIK42149.1 - 2.5e-13 50.8 0.0 1.5e-08 35.2 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIK42149.1 - 7.5e-12 45.2 0.0 2.1e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KIK42149.1 - 2e-07 30.7 0.0 6.2e-07 29.1 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KIK42149.1 - 0.0058 16.4 0.0 0.015 15.0 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DNA_III_psi PF03603.13 KIK42149.1 - 0.21 11.8 0.3 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 DNA polymerase III psi subunit Myb_DNA-bind_3 PF12776.7 KIK42150.1 - 1.2e-09 39.1 0.1 1.7e-09 38.5 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 KIK42151.1 - 0.0011 18.6 0.1 0.0013 18.4 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KIK42151.1 - 0.0064 16.1 0.0 0.007 16.0 0.0 1.0 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 KIK42151.1 - 0.0068 16.7 0.0 0.0083 16.5 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain BOP1NT PF08145.12 KIK42152.1 - 0.069 13.1 0.2 0.081 12.8 0.2 1.1 1 0 0 1 1 1 0 BOP1NT (NUC169) domain DUF3565 PF12088.8 KIK42154.1 - 0.078 12.9 0.3 0.095 12.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3565) HTH_Tnp_4 PF13613.6 KIK42155.1 - 0.00033 20.3 0.2 0.00039 20.1 0.2 1.1 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_38 PF13936.6 KIK42155.1 - 0.012 15.3 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain Myb_DNA-bind_3 PF12776.7 KIK42156.1 - 0.0039 18.2 0.2 0.0062 17.5 0.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KIK42156.1 - 0.0052 17.1 1.5 0.042 14.2 0.1 2.5 1 1 2 3 3 3 1 Myb/SANT-like DNA-binding domain p450 PF00067.22 KIK42159.1 - 5.4e-45 154.0 0.0 6.4e-45 153.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1765 PF08578.10 KIK42160.1 - 0.021 15.3 0.2 0.028 14.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1765) Integrase_Zn PF02022.19 KIK42162.1 - 0.14 12.1 0.2 0.2 11.6 0.2 1.2 1 0 0 1 1 1 0 Integrase Zinc binding domain Orn_Arg_deC_N PF02784.16 KIK42163.1 - 0.08 12.3 0.0 0.087 12.2 0.0 1.0 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Nop14 PF04147.12 KIK42165.1 - 0.25 9.5 11.0 0.39 8.9 11.0 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KIK42165.1 - 1.7 6.9 7.9 2.6 6.3 7.9 1.3 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.10 KIK42165.1 - 3.8 8.0 15.1 8.4 6.9 15.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KIK42165.1 - 6.6 5.9 14.2 12 5.1 14.2 1.4 1 0 0 1 1 1 0 NOA36 protein HMG_CoA_synt_C PF08540.10 KIK42166.1 - 5.1e-89 298.6 0.4 6.6e-89 298.2 0.4 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KIK42166.1 - 3.5e-85 284.3 0.1 5e-85 283.7 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.10 KIK42166.1 - 0.032 14.1 0.3 0.17 11.8 0.1 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF3641 PF12345.8 KIK42166.1 - 0.076 13.0 0.0 4.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) BTB PF00651.31 KIK42171.1 - 1.7e-20 73.3 0.0 5.2e-10 39.5 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.31 KIK42172.1 - 8.6e-10 38.8 0.1 1.6e-09 38.0 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KIK42173.1 - 3.6e-13 49.7 0.0 7.2e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KIK42174.1 - 3.3e-11 43.4 0.0 6.9e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain CDP-OH_P_transf PF01066.21 KIK42175.1 - 7.1e-14 52.3 1.5 7.1e-14 52.3 1.5 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PACT_coil_coil PF10495.9 KIK42176.1 - 4.7e-15 55.9 0.0 4.7e-15 55.9 0.0 4.7 5 0 0 5 5 5 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein ZapB PF06005.12 KIK42176.1 - 0.0095 16.4 6.9 0.0095 16.4 6.9 13.3 5 3 4 9 9 9 1 Cell division protein ZapB BTB PF00651.31 KIK42177.1 - 3e-07 30.7 0.0 9.9e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KIK42178.1 - 3.6e-11 43.3 0.0 8.5e-11 42.1 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain Transcrip_reg PF01709.20 KIK42178.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator LRRFIP PF09738.9 KIK42178.1 - 0.15 11.5 0.1 0.39 10.2 0.0 1.6 2 0 0 2 2 2 0 LRRFIP family zf-RING_2 PF13639.6 KIK42180.1 - 3e-07 30.6 11.1 3e-07 30.6 11.1 1.9 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KIK42180.1 - 4.5e-07 29.8 8.8 5.7e-07 29.5 6.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIK42180.1 - 5.1e-07 29.5 11.2 5.1e-07 29.5 11.2 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK42180.1 - 3.2e-06 26.9 12.9 3.2e-06 26.9 12.9 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK42180.1 - 3.7e-06 27.0 12.1 8.4e-06 25.8 12.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KIK42180.1 - 5.9e-06 26.0 13.1 5.9e-06 26.0 13.1 2.1 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK42180.1 - 0.00015 21.6 11.4 0.00015 21.6 11.4 1.9 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIK42180.1 - 0.00033 20.5 12.4 0.00033 20.5 12.4 1.7 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 SKA2 PF16740.5 KIK42180.1 - 0.015 15.0 0.2 0.045 13.5 0.1 1.9 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Atg14 PF10186.9 KIK42180.1 - 0.032 13.3 1.5 0.041 13.0 1.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KIK42180.1 - 0.041 14.4 1.9 0.09 13.3 1.9 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Syntaxin PF00804.25 KIK42180.1 - 0.14 11.8 1.9 0.48 10.1 2.2 1.7 2 0 0 2 2 2 0 Syntaxin zinc_ribbon_5 PF13719.6 KIK42180.1 - 0.23 11.3 0.1 0.23 11.3 0.1 2.8 3 0 0 3 3 2 0 zinc-ribbon domain zf-RING_6 PF14835.6 KIK42180.1 - 0.27 11.1 6.6 0.67 9.9 6.6 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF4051 PF13260.6 KIK42180.1 - 1.3 8.8 3.9 2.5 7.9 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4051) zf-RING_11 PF17123.5 KIK42180.1 - 1.3 8.8 14.2 0.55 10.0 11.0 2.0 2 0 0 2 2 2 0 RING-like zinc finger ISG65-75 PF11727.8 KIK42181.1 - 0.76 9.0 26.7 1.4 8.1 12.6 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein Glyco_transf_18 PF15024.6 KIK42181.1 - 2.5 6.6 4.8 3.6 6.1 4.8 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 18 OmpH PF03938.14 KIK42181.1 - 3.7 7.9 35.7 0.036 14.4 13.9 3.1 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) DUF3584 PF12128.8 KIK42181.1 - 9.6 3.6 36.3 19 2.6 36.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) NMO PF03060.15 KIK42182.1 - 3.6e-50 171.2 0.7 4.9e-50 170.8 0.7 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KIK42182.1 - 2.4e-07 30.1 0.2 1.3e-06 27.7 0.2 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KIK42182.1 - 0.0038 16.3 4.0 0.0062 15.6 4.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase BTB PF00651.31 KIK42184.1 - 5.1e-11 42.8 0.1 1.1e-10 41.7 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain WD40 PF00400.32 KIK42185.1 - 1.6e-38 130.0 19.8 3.3e-07 30.9 2.6 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42185.1 - 6.2e-17 61.7 3.1 1.4e-06 28.5 0.1 6.0 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK42185.1 - 4e-14 52.2 2.0 0.0051 15.5 0.1 5.1 2 1 2 5 5 5 5 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK42185.1 - 8.1e-06 25.4 0.0 9 5.5 0.0 5.2 2 2 4 6 6 6 2 WD40-like domain eIF2A PF08662.11 KIK42185.1 - 9.7e-05 22.3 0.1 0.0004 20.3 0.1 1.9 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK42185.1 - 0.00036 19.6 0.1 15 4.4 0.0 4.6 1 1 3 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KIK42185.1 - 0.00065 18.7 2.9 0.18 10.7 2.0 2.9 3 0 0 3 3 3 2 Partner and localizer of BRCA2 WD40 domain Nbas_N PF15492.6 KIK42185.1 - 0.011 15.1 0.3 4.3 6.6 0.0 3.7 1 1 3 4 4 4 0 Neuroblastoma-amplified sequence, N terminal RCC1_2 PF13540.6 KIK42185.1 - 0.023 14.5 0.5 0.082 12.7 0.1 2.3 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat Cytochrom_D1 PF02239.16 KIK42185.1 - 0.024 13.2 0.3 0.35 9.3 0.2 2.1 1 1 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 KIK42185.1 - 0.024 14.6 0.1 62 3.7 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PQQ PF01011.21 KIK42185.1 - 0.3 11.1 2.3 34 4.6 0.1 4.1 5 0 0 5 5 5 0 PQQ enzyme repeat DUF4875 PF16175.5 KIK42185.1 - 5.1 7.2 5.7 16 5.6 2.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4875) zf-MYND PF01753.18 KIK42187.1 - 2.6e-07 30.6 9.8 4.7e-07 29.8 9.8 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIK42187.1 - 0.0036 17.6 8.7 0.0069 16.7 8.7 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding KDZ PF18758.1 KIK42189.1 - 3.1e-47 161.0 0.0 6.6e-47 160.0 0.0 1.6 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Peptidase_C48 PF02902.19 KIK42189.1 - 1.1e-11 45.0 1.0 3.7e-11 43.3 0.8 1.9 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain CxC1 PF18802.1 KIK42189.1 - 0.021 15.0 0.0 0.059 13.5 0.0 1.7 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases Pico_P1A PF02226.16 KIK42190.1 - 0.082 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Picornavirus coat protein (VP4) zf-C2H2_4 PF13894.6 KIK42193.1 - 0.006 17.3 5.3 6.7 7.8 0.4 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK42193.1 - 0.3 11.6 10.0 1.3 9.6 0.2 3.9 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KIK42193.1 - 0.33 11.3 2.3 0.55 10.6 2.0 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KIK42193.1 - 8.9 6.9 6.1 11 6.6 0.4 3.5 4 0 0 4 4 4 0 Zinc-finger double domain Coprogen_oxidas PF01218.18 KIK42194.1 - 1.9e-110 368.3 0.0 2.1e-110 368.1 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Alpha-amylase PF00128.24 KIK42199.1 - 4.9e-116 388.0 0.2 7.1e-116 387.4 0.2 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KIK42199.1 - 1.6e-08 34.5 0.0 4.5e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Gemini_AL1_M PF08283.11 KIK42201.1 - 0.086 12.9 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Geminivirus rep protein central domain Pkinase PF00069.25 KIK42204.1 - 0.00048 19.6 0.0 0.059 12.7 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain LysM PF01476.20 KIK42206.1 - 1.2e-15 57.3 0.0 1.1e-06 28.6 0.0 2.2 2 0 0 2 2 2 2 LysM domain HU-HIG PF18291.1 KIK42206.1 - 0.034 14.2 0.0 0.048 13.7 0.0 1.2 1 0 0 1 1 1 0 HU domain fused to wHTH, Ig, or Glycine-rich motif DUF1943 PF09172.11 KIK42206.1 - 0.059 12.6 0.0 0.079 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) p450 PF00067.22 KIK42207.1 - 1e-64 219.1 0.0 1.2e-64 218.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Calreticulin PF00262.18 KIK42207.1 - 0.19 10.6 1.1 0.29 10.0 1.1 1.1 1 0 0 1 1 1 0 Calreticulin family p450 PF00067.22 KIK42208.1 - 1.3e-52 179.1 0.0 1e-44 153.1 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.16 KIK42209.1 - 3.7e-34 118.2 34.6 5.3e-34 117.7 34.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK42209.1 - 8.9e-13 47.9 7.4 8.9e-13 47.9 7.4 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter Shisa PF13908.6 KIK42211.1 - 0.14 12.4 0.1 0.23 11.7 0.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF1340 PF07067.11 KIK42211.1 - 0.15 11.5 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) DUF1459 PF07312.11 KIK42211.1 - 0.18 12.0 0.4 0.35 11.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) DUF1635 PF07795.11 KIK42212.1 - 0.017 15.0 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Phage_Gp23 PF10669.9 KIK42212.1 - 0.22 11.9 0.1 0.33 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DNA_pol_phi PF04931.13 KIK42212.1 - 5.3 5.0 6.3 6.8 4.7 6.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF805 PF05656.14 KIK42215.1 - 0.13 12.6 3.8 0.17 12.3 2.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF805) Cir_N PF10197.9 KIK42216.1 - 1e-06 28.8 0.2 1e-06 28.8 0.2 2.9 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF4551 PF15087.6 KIK42216.1 - 1.3 7.8 5.3 1.5 7.6 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Barttin PF15462.6 KIK42216.1 - 2.7 7.7 6.6 3.1 7.5 5.4 1.7 1 1 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) APC_u15 PF16636.5 KIK42216.1 - 6.7 7.2 8.5 0.34 11.4 1.2 2.7 2 2 1 3 3 3 0 Unstructured region on APC between APC_crr regions 5 and 6 p450 PF00067.22 KIK42217.1 - 9.2e-70 235.7 0.0 1e-69 235.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KIK42219.1 - 1e-10 41.3 0.3 3.1e-10 39.8 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 KIK42219.1 - 0.018 15.0 0.0 0.073 13.1 0.0 2.1 1 1 0 1 1 1 0 F-box-like domain F-box PF00646.33 KIK42219.1 - 0.023 14.6 0.4 0.023 14.6 0.4 2.6 3 0 0 3 3 3 0 F-box domain ERCC4 PF02732.15 KIK42221.1 - 0.0001 22.6 0.0 0.00016 21.9 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain p450 PF00067.22 KIK42222.1 - 1.1e-67 228.9 0.0 1.2e-67 228.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_tran_WecB PF03808.13 KIK42222.1 - 0.061 13.3 0.0 0.74 9.8 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family DUF4647 PF15504.6 KIK42222.1 - 0.17 10.9 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Pectate_lyase_3 PF12708.7 KIK42223.1 - 8.7e-93 310.1 17.3 8.6e-80 267.6 9.5 3.2 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KIK42223.1 - 1.3e-09 37.6 2.0 0.0011 18.6 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Pkinase PF00069.25 KIK42224.1 - 2e-61 207.7 0.0 2.1e-30 106.0 0.0 3.5 3 0 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.7 KIK42224.1 - 2.5e-43 148.5 3.0 8.6e-43 146.7 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 KIK42224.1 - 9.6e-29 100.4 0.0 7e-13 48.5 0.0 3.6 4 0 0 4 4 4 3 Protein tyrosine kinase RWD PF05773.22 KIK42224.1 - 1.1e-14 54.7 3.3 9.3e-13 48.5 0.0 4.0 4 0 0 4 4 4 1 RWD domain APH PF01636.23 KIK42224.1 - 1.2e-05 25.3 1.2 0.0001 22.3 0.0 3.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family tRNA-synt_His PF13393.6 KIK42224.1 - 3.7e-05 23.2 0.0 0.00011 21.6 0.0 1.8 1 1 0 1 1 1 1 Histidyl-tRNA synthetase FTA2 PF13095.6 KIK42224.1 - 0.0067 16.1 0.0 3 7.4 0.0 3.3 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIK42224.1 - 0.023 14.1 0.0 2.3 7.5 0.0 2.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Epimerase PF01370.21 KIK42225.1 - 3.3e-16 59.5 0.0 4.9e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK42225.1 - 9.7e-11 41.2 0.0 1.9e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KIK42225.1 - 7.6e-10 39.0 0.0 1.3e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KIK42225.1 - 1.1e-09 38.2 0.1 3e-08 33.5 0.0 2.4 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KIK42225.1 - 7.5e-09 35.1 0.0 3.9e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KIK42225.1 - 5.8e-06 26.0 0.0 9.2e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KIK42225.1 - 0.00026 20.5 0.2 0.0022 17.5 0.2 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK42225.1 - 0.016 15.1 0.1 0.18 11.7 0.1 2.1 1 1 0 1 1 1 0 KR domain adh_short_C2 PF13561.6 KIK42225.1 - 0.036 13.6 0.1 0.44 10.1 0.1 2.2 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase CHAT PF12770.7 KIK42231.1 - 5.6e-31 108.0 0.0 1.3e-30 106.8 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK42231.1 - 2.2e-11 43.2 15.9 0.011 15.6 0.0 8.5 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 KIK42231.1 - 2.4e-10 39.8 2.3 1.6 8.7 0.0 7.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIK42231.1 - 9.7e-10 38.6 10.8 0.39 11.0 0.2 8.2 2 2 4 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIK42231.1 - 2.1e-07 30.6 7.1 28 5.2 0.0 8.4 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK42231.1 - 1.4e-06 27.9 4.5 15 5.9 0.0 7.0 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK42231.1 - 4.1e-05 23.5 0.1 23 5.5 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat MIT PF04212.18 KIK42231.1 - 6.6e-05 22.9 0.2 7.9 6.6 0.0 6.2 6 0 0 6 6 6 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 KIK42231.1 - 0.00018 21.1 0.0 34 4.2 0.0 5.7 5 0 0 5 5 5 0 TPR repeat TPR_14 PF13428.6 KIK42231.1 - 0.0037 18.0 20.2 15 6.7 0.0 9.6 7 2 3 10 10 9 1 Tetratricopeptide repeat Vta1_C PF18097.1 KIK42231.1 - 0.29 10.9 0.0 0.29 10.9 0.0 6.4 7 0 0 7 7 7 0 Vta1 C-terminal domain CHAT PF12770.7 KIK42232.1 - 3.5e-31 108.7 0.0 6.9e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK42232.1 - 2e-17 62.4 12.4 0.00037 20.3 0.0 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 KIK42232.1 - 6.3e-09 35.3 3.1 4 7.4 0.0 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK42232.1 - 1.1e-07 32.0 18.8 0.045 14.0 0.3 8.0 3 2 6 9 9 9 5 Tetratricopeptide repeat TPR_7 PF13176.6 KIK42232.1 - 1.8e-06 27.6 4.1 2.5 8.3 0.0 6.7 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK42232.1 - 3.5e-06 26.7 6.5 14 6.1 0.0 7.8 8 0 0 8 8 7 1 Tetratricopeptide repeat MIT PF04212.18 KIK42232.1 - 2.7e-05 24.1 3.0 8.9 6.5 0.1 6.2 5 1 1 6 6 6 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 KIK42232.1 - 0.00021 20.9 0.0 21 4.9 0.0 5.3 5 0 0 5 5 5 0 TPR repeat TPR_8 PF13181.6 KIK42232.1 - 0.0043 17.1 0.0 1.9e+02 2.7 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat Zeta_toxin PF06414.12 KIK42232.1 - 0.094 12.0 0.1 0.21 10.9 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin TPR_14 PF13428.6 KIK42232.1 - 0.12 13.2 20.2 38 5.5 0.2 9.2 9 2 2 11 11 9 0 Tetratricopeptide repeat Med25_NR-box PF11244.8 KIK42234.1 - 0.059 13.8 0.5 0.079 13.4 0.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 25 C-terminal NR box-containing DUF2470 PF10615.9 KIK42235.1 - 6.3e-19 68.4 0.0 9.3e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 KIK42235.1 - 2.7e-07 30.8 0.9 5.7e-07 29.8 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) HNH_2 PF13391.6 KIK42238.1 - 0.00032 20.8 0.1 0.0019 18.3 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease HAUS5 PF14817.6 KIK42241.1 - 0.0027 16.6 5.5 0.0035 16.2 5.5 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 DUF3584 PF12128.8 KIK42241.1 - 0.0056 14.3 5.3 0.0073 13.9 5.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) ATG16 PF08614.11 KIK42241.1 - 0.036 14.3 8.0 0.054 13.7 8.0 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 KIK42241.1 - 0.039 13.5 1.4 0.048 13.2 1.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 KIK42241.1 - 0.074 12.1 5.9 0.13 11.4 5.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KIK42241.1 - 0.12 12.5 5.1 0.17 12.0 5.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ax_dynein_light PF10211.9 KIK42241.1 - 0.13 12.2 7.4 0.22 11.5 7.4 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain Spc7 PF08317.11 KIK42241.1 - 0.24 10.2 10.0 0.34 9.7 10.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3552 PF12072.8 KIK42241.1 - 0.6 9.5 12.6 0.89 8.9 12.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) ARGLU PF15346.6 KIK42241.1 - 0.67 9.8 13.7 1 9.2 13.7 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 GrpE PF01025.19 KIK42241.1 - 0.71 9.5 8.8 0.53 9.9 6.0 1.9 1 1 1 2 2 2 0 GrpE ADIP PF11559.8 KIK42241.1 - 0.88 9.7 13.3 2.3 8.3 13.2 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding OmpH PF03938.14 KIK42241.1 - 1.3 9.4 10.5 2.1 8.7 10.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 KIK42241.1 - 2.2 8.9 9.6 12 6.6 9.0 2.2 1 1 1 2 2 2 0 SlyX p450 PF00067.22 KIK42243.1 - 1.1e-60 205.7 0.0 2.2e-60 204.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 P22_CoatProtein PF11651.8 KIK42244.1 - 0.16 10.6 0.0 0.18 10.3 0.0 1.0 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 MFS_1 PF07690.16 KIK42245.1 - 4.3e-36 124.6 26.0 6.6e-36 124.0 26.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily GMC_oxred_N PF00732.19 KIK42249.1 - 1.3e-56 192.1 0.0 1.7e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK42249.1 - 2.7e-26 92.8 0.0 4.9e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 KIK42249.1 - 0.0039 16.5 0.0 0.46 9.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK42249.1 - 0.0065 15.7 0.1 0.02 14.2 0.1 1.7 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KIK42249.1 - 0.015 14.9 0.6 0.13 11.8 0.4 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK42249.1 - 0.025 14.8 1.1 0.072 13.3 1.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK42249.1 - 0.034 13.2 0.2 0.063 12.3 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KIK42249.1 - 0.071 12.3 0.1 0.64 9.2 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK42249.1 - 0.12 13.0 0.2 0.29 11.7 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1765 PF08578.10 KIK42249.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1765) FAD_binding_3 PF01494.19 KIK42249.1 - 0.15 11.2 0.1 0.23 10.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.21 KIK42250.1 - 1.3e-15 57.4 0.0 3e-15 56.3 0.0 1.5 1 1 0 1 1 1 1 ThiF family Sld5 PF05916.11 KIK42251.1 - 5.9e-05 23.5 0.1 9.6e-05 22.8 0.1 1.4 1 1 0 1 1 1 1 GINS complex protein Synaptonemal_3 PF15191.6 KIK42251.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 LysM PF01476.20 KIK42253.1 - 9.2e-09 35.2 0.9 0.0025 17.8 0.1 2.2 2 0 0 2 2 2 2 LysM domain SPX PF03105.19 KIK42254.1 - 2.6e-38 133.0 6.5 1.5e-37 130.5 6.5 2.0 1 1 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 KIK42254.1 - 6.4e-09 35.5 5.0 1.1e-08 34.8 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK42254.1 - 1.8e-06 28.0 7.0 3.5e-06 27.1 7.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KIK42254.1 - 3.2e-06 26.9 6.6 5.7e-06 26.1 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK42254.1 - 3.3e-06 27.3 6.8 5.8e-06 26.5 6.8 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KIK42254.1 - 1e-05 25.3 6.8 1.8e-05 24.5 6.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KIK42254.1 - 8.1e-05 22.5 6.6 0.00015 21.6 6.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIK42254.1 - 0.00013 21.9 3.8 0.00013 21.9 3.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIK42254.1 - 0.00024 20.9 7.4 0.00052 19.8 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KIK42254.1 - 0.0016 18.3 2.6 0.0032 17.3 2.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KIK42254.1 - 0.0051 16.9 4.0 0.0092 16.1 4.0 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KIK42254.1 - 0.0051 16.6 3.3 0.011 15.5 3.3 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KIK42254.1 - 0.035 14.4 2.8 0.075 13.3 2.8 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain FlxA PF14282.6 KIK42254.1 - 0.9 9.6 6.0 2.1 8.4 6.0 1.5 1 0 0 1 1 1 0 FlxA-like protein PCRF PF03462.18 KIK42255.1 - 1.3e-51 175.3 0.1 9e-51 172.5 0.0 2.1 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KIK42255.1 - 4.3e-34 116.9 4.9 7.4e-34 116.2 4.9 1.4 1 0 0 1 1 1 1 RF-1 domain MMR_HSR1 PF01926.23 KIK42256.1 - 4.2e-11 42.9 0.0 5.7e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK42256.1 - 2.4e-05 24.3 0.0 6.4e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KIK42256.1 - 2.7e-05 24.3 0.1 5.7e-05 23.2 0.1 1.5 1 1 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 KIK42256.1 - 0.00022 21.8 0.0 0.00035 21.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KIK42256.1 - 0.00058 20.3 0.0 0.0012 19.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AIG1 PF04548.16 KIK42256.1 - 0.00076 18.9 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 KIK42256.1 - 0.0073 16.5 0.0 0.037 14.2 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KIK42256.1 - 0.009 16.3 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Ras PF00071.22 KIK42256.1 - 0.02 14.5 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Ras family FeoB_N PF02421.18 KIK42256.1 - 0.022 14.3 0.0 0.082 12.4 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_23 PF13476.6 KIK42256.1 - 0.041 14.4 0.1 0.064 13.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KIK42256.1 - 0.043 13.1 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 KIK42256.1 - 0.044 13.5 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 KIK42256.1 - 0.07 11.9 0.0 0.096 11.5 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_29 PF13555.6 KIK42256.1 - 0.072 12.8 0.2 0.15 11.8 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KIK42256.1 - 0.1 12.1 0.0 11 5.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KIK42256.1 - 0.11 12.3 0.0 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 KIK42256.1 - 0.12 12.5 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain RNA_helicase PF00910.22 KIK42256.1 - 0.15 12.4 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.13 KIK42256.1 - 0.22 10.7 0.0 0.36 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RSN1_7TM PF02714.15 KIK42257.1 - 1.2e-81 274.0 25.1 2.1e-81 273.3 25.1 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KIK42257.1 - 4.1e-35 121.6 0.0 5.9e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KIK42257.1 - 6.8e-34 116.9 2.1 6.8e-34 116.9 2.1 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport RRM_1 PF00076.22 KIK42257.1 - 0.023 14.5 0.1 0.58 10.0 0.1 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_assoc3 PF16637.5 KIK42257.1 - 0.063 13.5 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Putative zinc-finger between two C2H2 zinc-fingers on Patz zf-MYND PF01753.18 KIK42260.1 - 2e-11 43.8 15.7 4e-11 42.8 15.7 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIK42260.1 - 0.023 15.0 14.5 0.053 13.8 14.5 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Rhodanese_C PF12368.8 KIK42260.1 - 0.13 12.7 5.6 0.25 11.8 5.6 1.4 1 0 0 1 1 1 0 Rhodanase C-terminal Reovirus_cap PF00979.17 KIK42260.1 - 0.15 11.2 0.9 0.22 10.7 0.9 1.2 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 zf-HIT PF04438.16 KIK42260.1 - 0.64 9.9 8.4 1.5 8.8 8.4 1.6 1 0 0 1 1 1 0 HIT zinc finger Phage_portal_2 PF05136.13 KIK42261.1 - 0.15 11.2 0.2 0.23 10.6 0.2 1.3 1 0 0 1 1 1 0 Phage portal protein, lambda family DUF3012 PF11216.8 KIK42261.1 - 0.29 11.2 3.4 0.63 10.1 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) BTB PF00651.31 KIK42263.1 - 0.0033 17.6 0.0 0.0083 16.3 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain DUF3012 PF11216.8 KIK42263.1 - 0.68 10.0 5.3 1.3 9.1 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) Pet100 PF09803.9 KIK42266.1 - 3.5e-26 91.5 0.0 4.4e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Pet100 Luteo_PO PF04662.13 KIK42266.1 - 0.014 15.0 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 Luteovirus P0 protein PALP PF00291.25 KIK42267.1 - 2e-53 181.7 0.1 3.1e-53 181.1 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AlaDh_PNT_C PF01262.21 KIK42267.1 - 0.0005 19.4 0.2 0.00093 18.5 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain zf-C2H2 PF00096.26 KIK42269.1 - 5.5e-07 29.7 11.2 0.00021 21.6 1.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK42269.1 - 0.00032 21.0 4.1 0.00032 21.0 4.1 2.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK42269.1 - 0.00094 19.8 10.8 0.15 13.0 2.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger DUF3008 PF11450.8 KIK42269.1 - 0.0073 16.4 0.5 0.033 14.3 0.5 2.1 1 0 0 1 1 1 1 Protein of unknwon function (DUF3008) DUF3844 PF12955.7 KIK42269.1 - 0.14 12.3 0.7 0.28 11.3 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) zf-H2C2_5 PF13909.6 KIK42269.1 - 1.9 8.3 5.2 4.6 7.1 1.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Brix PF04427.18 KIK42270.1 - 4.3e-41 141.1 0.0 7.1e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Brix domain SCAB-PH PF17684.1 KIK42270.1 - 0.086 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 PH domain of plant-specific actin-binding protein Hamartin PF04388.12 KIK42271.1 - 0.0013 17.5 15.3 0.0016 17.2 15.3 1.2 1 0 0 1 1 1 1 Hamartin protein OppC_N PF12911.7 KIK42271.1 - 0.01 15.8 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C OAD_gamma PF04277.13 KIK42271.1 - 0.039 14.5 0.0 0.2 12.3 0.0 2.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Amnionless PF14828.6 KIK42271.1 - 0.047 12.5 0.0 0.067 12.0 0.0 1.1 1 0 0 1 1 1 0 Amnionless Ctr PF04145.15 KIK42271.1 - 0.056 14.1 2.3 0.15 12.7 0.0 2.4 1 1 0 2 2 2 0 Ctr copper transporter family Stevor PF17410.2 KIK42271.1 - 0.13 11.8 0.2 0.19 11.2 0.2 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Cation_ATPase_C PF00689.21 KIK42271.1 - 0.14 11.9 0.3 0.2 11.3 0.3 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Apt1 PF10351.9 KIK42271.1 - 7.7 5.3 5.6 11 4.7 5.6 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain CdiI_3 PF18616.1 KIK42274.1 - 0.11 12.4 0.1 0.6 10.0 0.1 2.1 3 0 0 3 3 3 0 CDI immunity proteins MMR_HSR1 PF01926.23 KIK42275.1 - 4.5e-05 23.5 0.0 5.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KIK42275.1 - 0.00024 20.6 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KIK42275.1 - 0.00083 19.6 0.1 0.0012 19.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KIK42275.1 - 0.0021 17.3 0.0 0.0023 17.2 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit RsgA_GTPase PF03193.16 KIK42275.1 - 0.0027 17.6 0.0 0.0039 17.1 0.0 1.1 1 0 0 1 1 1 1 RsgA GTPase ATPase_2 PF01637.18 KIK42275.1 - 0.01 15.7 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 KIK42275.1 - 0.012 15.0 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein FeoB_N PF02421.18 KIK42275.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.18 KIK42275.1 - 0.029 13.6 0.1 0.036 13.3 0.1 1.2 1 1 0 1 1 1 0 Septin AAA PF00004.29 KIK42275.1 - 0.03 14.8 0.0 0.032 14.7 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KIK42275.1 - 0.038 13.2 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 KIK42275.1 - 0.039 14.5 0.0 0.046 14.2 0.0 1.2 1 0 0 1 1 1 0 ABC transporter F-box PF00646.33 KIK42276.1 - 5.4e-05 22.9 2.2 0.00011 22.0 0.8 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIK42276.1 - 0.00017 21.4 1.2 0.0005 19.9 1.2 1.8 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.25 KIK42277.1 - 7.5e-40 136.9 0.1 3.5e-20 72.5 0.1 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK42277.1 - 1.5e-14 54.0 0.3 0.00024 20.5 0.1 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase PrmA PF06325.13 KIK42277.1 - 0.085 12.2 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RIO1 PF01163.22 KIK42277.1 - 0.17 11.5 0.1 0.39 10.3 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 KIK42277.1 - 0.18 10.7 0.0 0.28 10.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AAA_23 PF13476.6 KIK42278.1 - 0.18 12.2 4.5 0.23 11.9 4.5 1.2 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 KIK42278.1 - 1.5 7.6 15.1 2 7.2 15.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2752 PF10825.8 KIK42280.1 - 0.021 14.9 0.0 0.051 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) F-box-like PF12937.7 KIK42281.1 - 0.00034 20.4 0.1 0.00094 19.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIK42283.1 - 5.5e-10 39.0 0.2 5.5e-10 39.0 0.2 3.4 4 0 0 4 4 4 1 F-box-like F-box PF00646.33 KIK42283.1 - 0.0002 21.2 0.1 0.0007 19.4 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK42284.1 - 1.1e-09 38.0 0.4 1.1e-09 38.0 0.4 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK42284.1 - 0.00017 21.4 0.2 0.00064 19.5 0.2 2.0 1 0 0 1 1 1 1 F-box domain MMR_HSR1 PF01926.23 KIK42286.1 - 1.7e-11 44.2 0.0 2e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK42286.1 - 2.4e-07 30.3 0.0 2.6e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIK42286.1 - 5.6e-06 26.5 0.1 1.1e-05 25.5 0.1 1.6 1 1 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 KIK42286.1 - 0.00032 20.7 0.1 0.00052 20.0 0.1 1.5 1 1 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 KIK42286.1 - 0.0041 17.6 0.1 0.0049 17.4 0.1 1.3 1 1 0 1 1 1 1 ABC transporter Roc PF08477.13 KIK42286.1 - 0.021 15.0 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK42286.1 - 0.023 14.2 0.0 0.029 13.8 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_22 PF13401.6 KIK42286.1 - 0.044 14.0 0.1 0.21 11.8 0.0 2.0 1 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIK42286.1 - 0.05 14.0 0.1 0.05 14.0 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 KIK42286.1 - 0.052 13.1 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF815 PF05673.13 KIK42286.1 - 0.084 12.0 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_13 PF13166.6 KIK42286.1 - 0.12 11.0 0.0 0.13 10.9 0.0 1.0 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 KIK42286.1 - 0.19 10.8 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Zeta_toxin PF06414.12 KIK42286.1 - 0.21 10.8 0.1 0.3 10.3 0.1 1.2 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 KIK42287.1 - 2e-12 47.2 0.6 3.2e-12 46.6 0.6 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KIK42287.1 - 9.8e-09 35.5 0.1 5.5e-08 33.0 0.1 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KIK42287.1 - 4.6e-08 32.8 0.4 2e-07 30.7 0.4 1.9 1 1 0 1 1 1 1 Ras family AIG1 PF04548.16 KIK42287.1 - 3.2e-06 26.6 0.2 3.8e-06 26.4 0.2 1.1 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KIK42287.1 - 1.7e-05 24.8 0.0 3.8e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KIK42287.1 - 0.00014 22.3 0.2 0.00085 19.8 0.0 2.2 2 1 0 3 3 3 1 AAA ATPase domain Dynamin_N PF00350.23 KIK42287.1 - 0.00018 21.6 1.7 0.0038 17.3 0.6 2.2 1 1 1 2 2 2 1 Dynamin family Septin PF00735.18 KIK42287.1 - 0.00089 18.6 0.2 0.0012 18.2 0.2 1.2 1 0 0 1 1 1 1 Septin ABC_tran PF00005.27 KIK42287.1 - 0.0014 19.2 0.4 0.0029 18.1 0.4 1.6 1 1 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 KIK42287.1 - 0.0043 17.6 0.0 0.0064 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK42287.1 - 0.0069 16.7 0.2 0.016 15.4 0.2 1.7 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 KIK42287.1 - 0.0069 15.8 0.1 0.13 11.6 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein Sigma54_activat PF00158.26 KIK42287.1 - 0.024 14.4 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 KIK42287.1 - 0.027 14.2 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.13 KIK42287.1 - 0.056 12.5 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) MCM PF00493.23 KIK42287.1 - 0.066 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain DUF815 PF05673.13 KIK42287.1 - 0.073 12.2 0.0 0.15 11.2 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SRPRB PF09439.10 KIK42287.1 - 0.074 12.5 0.5 0.17 11.3 0.5 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KIK42287.1 - 0.088 12.3 2.1 0.25 10.9 2.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B RNA_helicase PF00910.22 KIK42287.1 - 0.1 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KIK42287.1 - 0.11 12.3 0.2 0.7 9.8 0.0 2.2 3 0 0 3 3 3 0 NACHT domain FtsK_SpoIIIE PF01580.18 KIK42287.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF87 PF01935.17 KIK42287.1 - 0.15 12.1 0.2 0.3 11.1 0.2 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 KIK42291.1 - 1.8e-12 47.3 0.2 2.4e-12 47.0 0.2 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KIK42291.1 - 7.4e-07 29.4 1.7 0.0012 18.9 0.4 2.1 1 1 1 2 2 2 2 Dynamin family Ras PF00071.22 KIK42291.1 - 1.7e-06 27.8 0.1 0.0001 22.0 0.1 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KIK42291.1 - 9.5e-06 25.8 0.0 0.00031 21.0 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KIK42291.1 - 6.7e-05 22.3 0.1 7.5e-05 22.1 0.1 1.1 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 KIK42291.1 - 0.0001 22.9 0.4 0.00015 22.2 0.3 1.6 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KIK42291.1 - 0.0054 16.6 0.7 0.013 15.4 0.3 1.8 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 KIK42291.1 - 0.021 14.3 0.5 0.19 11.2 0.5 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF87 PF01935.17 KIK42291.1 - 0.029 14.5 1.9 0.052 13.6 0.9 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain FeoB_N PF02421.18 KIK42291.1 - 0.049 13.2 0.6 0.16 11.5 0.6 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_23 PF13476.6 KIK42291.1 - 0.068 13.7 0.7 0.13 12.7 0.4 1.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIK42291.1 - 0.15 12.5 0.3 0.26 11.7 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 KIK42291.1 - 0.17 11.2 0.0 0.4 10.0 0.0 1.5 1 1 1 2 2 2 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIK42292.1 - 4.5e-10 39.6 0.0 7.3e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK42292.1 - 7.5e-08 32.0 0.0 1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIK42292.1 - 0.00035 20.7 0.0 0.0006 19.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 KIK42292.1 - 0.00088 19.8 0.2 0.0024 18.4 0.2 2.0 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KIK42292.1 - 0.0018 18.2 0.0 0.0044 16.9 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 KIK42292.1 - 0.026 14.2 0.0 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KIK42292.1 - 0.029 14.6 0.1 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 KIK42292.1 - 0.039 13.1 0.1 0.077 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 KIK42292.1 - 0.049 13.9 0.0 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIK42292.1 - 0.082 13.3 0.0 0.13 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain CBFD_NFYB_HMF PF00808.23 KIK42293.1 - 2.3e-27 95.1 0.8 3e-27 94.7 0.8 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK42293.1 - 2e-05 25.0 0.0 3.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KIK42293.1 - 0.0027 17.8 0.1 0.0034 17.5 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 KIK42293.1 - 0.0051 16.8 0.0 0.0081 16.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KIK42293.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 1 0 1 1 1 0 Bromodomain associated Ribosomal_L14e PF01929.17 KIK42294.1 - 4.4e-33 113.6 0.3 7.1e-33 112.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 KIK42294.1 - 1.8e-05 24.5 0.1 3.2e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 KOW motif NUC153 PF08159.12 KIK42296.1 - 1.6e-14 53.4 14.4 4.3e-14 52.0 1.5 3.8 3 0 0 3 3 3 3 NUC153 domain Atg14 PF10186.9 KIK42297.1 - 2.7e-41 141.7 0.0 5.5e-41 140.7 0.0 1.4 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 YscO PF07321.12 KIK42297.1 - 0.14 12.1 5.8 0.22 11.5 5.8 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO UPF0184 PF03670.13 KIK42297.1 - 0.14 12.5 0.2 0.24 11.8 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) WD40 PF00400.32 KIK42298.1 - 2.5e-41 138.9 15.9 2.3e-08 34.6 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42298.1 - 6.6e-15 55.2 0.1 0.0064 16.8 0.0 4.9 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK42298.1 - 4.5e-05 22.3 0.8 0.12 11.0 0.5 3.5 1 1 2 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK42298.1 - 0.0054 16.1 0.1 1.6 8.0 0.0 2.5 2 1 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 KIK42298.1 - 0.013 14.4 0.0 11 4.8 0.0 3.7 2 2 3 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK42298.1 - 0.024 14.0 0.0 9.5 5.4 0.1 2.2 1 1 0 2 2 2 0 WD40-like domain WD40 PF00400.32 KIK42299.1 - 3.9e-43 144.6 12.4 2.3e-09 37.7 0.1 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42299.1 - 2.4e-13 50.2 0.0 0.0079 16.5 0.0 4.9 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK42299.1 - 0.00011 21.1 0.1 0.32 9.6 0.1 3.5 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK42299.1 - 0.021 13.8 0.0 7.9 5.3 0.0 3.7 1 1 3 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KIK42299.1 - 0.065 11.7 0.0 0.11 11.0 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain WD40_like PF17005.5 KIK42299.1 - 0.21 10.9 0.0 56 2.9 0.0 2.7 1 1 0 2 2 2 0 WD40-like domain PD40 PF07676.12 KIK42299.1 - 1 9.4 4.6 36 4.4 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PAPA-1 PF04795.12 KIK42301.1 - 1.4e-19 70.6 9.8 1.4e-19 70.6 9.8 2.6 3 0 0 3 3 3 1 PAPA-1-like conserved region DUF5364 PF17322.2 KIK42301.1 - 0.00023 21.5 13.1 0.0031 17.9 4.9 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF5364) PAD PF03068.15 KIK42301.1 - 0.13 11.3 0.1 0.17 10.8 0.1 1.1 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) Pex14_N PF04695.13 KIK42301.1 - 8.5 7.0 20.5 0.23 12.1 3.8 2.3 1 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase_Tyr PF07714.17 KIK42302.1 - 8.5e-39 133.4 0.0 1.3e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK42302.1 - 6.4e-37 127.3 0.0 1e-36 126.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KIK42302.1 - 0.0001 21.7 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KIK42302.1 - 0.00065 19.4 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KIK42302.1 - 0.0011 17.8 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIK42302.1 - 0.0056 16.0 0.0 0.0084 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK42302.1 - 0.056 13.4 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KIK42302.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FluMu_N PF17891.1 KIK42303.1 - 0.31 10.8 2.1 3.6 7.4 0.0 2.6 2 1 1 3 3 3 0 Mu-like prophage FluMu N-terminal domain WD40 PF00400.32 KIK42306.1 - 3.6e-30 103.5 21.1 9e-07 29.5 0.3 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42306.1 - 4.4e-13 49.3 0.2 0.00089 19.5 0.0 4.4 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WW PF00397.26 KIK42306.1 - 4.9e-07 29.7 2.8 2.8e-06 27.3 0.3 3.2 2 0 0 2 2 2 1 WW domain Nup160 PF11715.8 KIK42306.1 - 0.00069 18.4 0.4 1.7 7.2 0.1 3.6 3 1 1 4 4 4 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK42306.1 - 0.0011 18.1 0.0 0.36 9.7 0.0 3.4 2 2 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KIK42307.1 - 3.1e-31 106.9 21.7 1.9e-08 34.8 0.2 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42307.1 - 3.8e-14 52.7 0.4 0.00071 19.8 0.0 4.3 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WW PF00397.26 KIK42307.1 - 6.6e-06 26.1 1.4 6.6e-06 26.1 1.4 2.9 2 0 0 2 2 2 1 WW domain Ge1_WD40 PF16529.5 KIK42307.1 - 2.4e-05 23.5 0.0 0.22 10.5 0.0 3.0 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK42307.1 - 0.0006 18.6 0.1 0.24 10.0 0.0 3.3 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK42307.1 - 0.0085 15.4 0.1 1.5 8.0 0.0 3.0 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal WD40 PF00400.32 KIK42311.1 - 3.7e-35 119.3 17.9 9e-10 39.0 0.3 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42311.1 - 5.9e-14 52.1 0.5 0.028 14.7 0.0 5.1 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK42311.1 - 9.3e-07 27.9 0.1 0.038 12.6 0.0 3.3 3 0 0 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK42311.1 - 8.7e-06 24.9 0.0 0.14 11.1 0.0 3.5 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK42311.1 - 0.00069 19.6 0.0 0.24 11.3 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KIK42311.1 - 0.0095 15.3 0.4 3.5 6.9 0.0 3.2 2 2 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal WD40 PF00400.32 KIK42313.1 - 2.3e-34 116.9 18.2 8e-08 32.8 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42313.1 - 6.3e-14 52.0 0.5 0.0028 17.9 0.0 4.6 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK42313.1 - 2.3e-07 29.9 0.2 0.063 11.9 0.0 4.0 3 1 1 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK42313.1 - 1.1e-06 27.9 0.0 3.2 6.6 0.0 4.6 2 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK42313.1 - 0.0022 17.9 0.0 0.03 14.2 0.0 2.4 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK42313.1 - 0.58 10.2 5.0 39 4.4 0.0 4.9 5 1 0 5 5 5 0 WD40-like Beta Propeller Repeat Adeno_E3 PF06040.11 KIK42315.1 - 0.19 11.9 0.0 0.21 11.8 0.0 1.1 1 0 0 1 1 1 0 Adenovirus E3 protein Cys_Met_Meta_PP PF01053.20 KIK42316.1 - 4.7e-20 71.5 0.1 5e-20 71.4 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme WD40 PF00400.32 KIK42318.1 - 6e-18 64.9 12.0 2.2e-11 44.1 0.5 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42318.1 - 7.5e-06 26.2 0.2 0.0037 17.5 0.0 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK42318.1 - 0.0046 15.7 0.2 0.034 12.8 0.1 1.8 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK42318.1 - 0.0064 15.5 0.0 0.0067 15.4 0.0 1.3 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK42318.1 - 0.37 10.8 5.1 24 5.0 0.1 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 KIK42319.1 - 3.6e-13 49.8 5.1 0.0031 18.3 0.0 3.9 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42319.1 - 4.9e-07 30.0 0.1 0.021 15.1 0.0 3.1 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK42319.1 - 0.024 13.6 0.0 0.32 9.9 0.0 2.0 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KIK42322.1 - 4e-35 119.2 17.1 6.8e-08 33.1 0.2 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42322.1 - 1.8e-17 63.4 0.6 8e-05 22.9 0.0 4.8 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK42322.1 - 6.7e-05 21.7 4.2 0.0065 15.2 0.5 4.2 2 1 1 4 4 4 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK42322.1 - 0.00024 20.2 0.0 3 6.7 0.0 4.2 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK42322.1 - 0.0018 18.2 0.0 0.079 12.8 0.0 2.7 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KIK42322.1 - 0.03 12.4 0.3 0.37 8.7 0.3 2.5 1 1 0 1 1 1 0 IKI3 family ODC_AZ PF02100.17 KIK42325.1 - 0.19 11.7 0.2 0.23 11.4 0.2 1.2 1 0 0 1 1 1 0 Ornithine decarboxylase antizyme CHAT PF12770.7 KIK42327.1 - 1.1e-28 100.5 0.0 2.2e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 KIK42327.1 - 8.9e-08 32.3 6.5 0.33 11.3 1.0 6.5 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 KIK42327.1 - 2.2e-07 30.5 10.7 0.12 12.3 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIK42327.1 - 0.0002 21.0 0.5 1.5 8.6 0.0 4.4 4 0 0 4 4 4 1 TPR repeat TPR_7 PF13176.6 KIK42327.1 - 0.0017 18.2 5.5 6.5 7.0 0.1 5.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK42327.1 - 0.0061 16.6 5.0 10 6.5 0.1 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK42327.1 - 0.0099 15.7 6.9 15 5.6 0.1 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat RPN7 PF10602.9 KIK42327.1 - 0.11 12.2 0.0 0.33 10.6 0.0 1.9 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_16 PF13432.6 KIK42327.1 - 0.25 12.0 7.4 1.9 9.2 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat PCI PF01399.27 KIK42328.1 - 8.4e-07 29.5 0.0 2.1e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 PCI domain FMN_red PF03358.15 KIK42329.1 - 2e-06 27.6 0.0 2.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 KIK42329.1 - 0.026 14.7 0.1 0.23 11.6 0.1 2.1 1 1 0 1 1 1 0 Flavodoxin FMN_red PF03358.15 KIK42330.1 - 7.1e-08 32.3 0.0 9.4e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KIK42330.1 - 3.2e-06 27.0 0.0 4.1e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KIK42330.1 - 0.0018 18.5 0.2 0.0053 17.0 0.2 1.9 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 KIK42330.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.7 1 1 1 2 2 2 0 Flavodoxin domain RRP7 PF12923.7 KIK42331.1 - 3.3e-28 98.2 6.7 7.3e-28 97.1 6.7 1.6 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 KIK42331.1 - 6.6e-13 48.8 0.1 1.3e-12 47.8 0.1 1.4 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 KIK42331.1 - 0.00029 20.6 0.0 0.00092 19.0 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRIM-19 PF06212.12 KIK42331.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 GRIM-19 protein DUF5093 PF17011.5 KIK42331.1 - 0.25 11.6 0.1 0.25 11.6 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5093) PLAC8 PF04749.17 KIK42332.1 - 2.4e-23 83.0 8.4 3.1e-23 82.6 8.4 1.1 1 0 0 1 1 1 1 PLAC8 family TGF_beta_GS PF08515.12 KIK42332.1 - 0.26 10.8 0.7 0.6 9.7 0.7 1.6 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Hydrophobin PF01185.18 KIK42333.1 - 1e-22 80.5 12.7 1.2e-22 80.3 12.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin AdoMet_MTase PF07757.13 KIK42334.1 - 2.7e-32 111.4 0.0 5.2e-31 107.3 0.0 2.2 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.6 KIK42334.1 - 0.0008 19.3 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK42334.1 - 0.0068 17.0 0.0 0.013 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK42334.1 - 0.014 16.1 0.0 0.031 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KIK42334.1 - 0.058 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KIK42334.1 - 0.12 12.4 0.3 0.41 10.6 0.3 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KIK42334.1 - 0.26 11.0 0.2 0.46 10.3 0.2 1.3 1 0 0 1 1 1 0 Methyltransferase domain CENP-B_dimeris PF09026.10 KIK42335.1 - 3.4 8.1 9.2 7.2 7.1 9.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain WD40 PF00400.32 KIK42337.1 - 3.4e-42 141.6 21.6 1.1e-07 32.4 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42337.1 - 4.1e-11 43.0 1.2 0.2 12.0 0.1 5.0 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WW PF00397.26 KIK42337.1 - 2e-06 27.7 0.5 2e-06 27.7 0.5 3.5 3 0 0 3 3 3 1 WW domain Nup160 PF11715.8 KIK42337.1 - 4.4e-06 25.6 0.5 0.054 12.1 0.4 4.1 2 1 1 4 4 4 2 Nucleoporin Nup120/160 DUF3558 PF12079.8 KIK42337.1 - 0.13 12.3 0.6 2.2 8.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3558) Ge1_WD40 PF16529.5 KIK42337.1 - 0.13 11.2 0.1 25 3.7 0.0 3.1 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KIK42341.1 - 1.7e-14 53.9 2.0 2.1e-07 31.5 0.1 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.8 KIK42341.1 - 0.0052 15.5 0.4 0.034 12.8 0.1 1.8 1 1 1 2 2 2 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KIK42341.1 - 0.0085 16.4 0.1 0.66 10.3 0.1 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 KIK42341.1 - 0.058 12.5 0.0 0.065 12.3 0.0 1.0 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain Cytochrom_D1 PF02239.16 KIK42341.1 - 0.12 10.8 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Cytochrome D1 heme domain Glyco_hydro_79C PF16862.5 KIK42352.1 - 4e-22 79.0 2.3 7.7e-22 78.1 0.2 2.5 1 1 1 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain F-box PF00646.33 KIK42353.1 - 0.0016 18.3 0.1 0.006 16.4 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK42353.1 - 0.036 14.0 1.4 0.08 12.9 0.3 2.1 2 0 0 2 2 2 0 F-box-like F-box_4 PF15966.5 KIK42353.1 - 0.039 13.8 0.0 0.099 12.5 0.0 1.6 1 0 0 1 1 1 0 F-box Chitin_bind_4 PF00379.23 KIK42356.1 - 0.0069 16.9 2.8 0.12 12.9 3.1 2.3 2 1 0 2 2 2 1 Insect cuticle protein PRiA4_ORF3 PF07929.11 KIK42358.1 - 3.5e-26 92.0 0.1 6.7e-26 91.0 0.0 1.5 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein zf-MYND PF01753.18 KIK42358.1 - 4.4e-11 42.7 10.7 7.2e-11 42.0 10.7 1.4 1 0 0 1 1 1 1 MYND finger Whi5 PF08528.11 KIK42360.1 - 0.00015 21.3 0.0 0.0003 20.3 0.0 1.5 1 0 0 1 1 1 1 Whi5 like RAI1 PF08652.11 KIK42361.1 - 5.5e-21 74.5 0.0 1e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease RMI1_C PF16099.5 KIK42361.1 - 0.0066 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold zf-C2H2 PF00096.26 KIK42366.1 - 1.7e-14 53.3 13.4 4.9e-05 23.6 0.2 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK42366.1 - 3.9e-11 42.9 14.0 3e-05 24.2 0.2 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK42366.1 - 9.2e-11 41.6 12.2 0.0012 19.4 0.1 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KIK42366.1 - 2e-06 27.7 2.6 0.0061 16.5 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KIK42366.1 - 2.9e-05 24.3 6.4 0.00079 19.7 0.0 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIK42366.1 - 7.9e-05 22.8 4.3 0.0049 17.1 0.0 3.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KIK42366.1 - 0.0011 19.5 11.1 0.29 11.8 2.4 3.5 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KIK42366.1 - 0.0012 19.0 3.7 0.0052 17.1 3.0 1.9 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KIK42366.1 - 0.0059 16.8 3.1 2.1 8.5 0.0 3.0 1 1 2 3 3 3 2 Aberrant zinc-finger zf-C2H2_2 PF12756.7 KIK42366.1 - 0.0095 16.3 1.6 0.51 10.7 0.4 2.4 1 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 KIK42366.1 - 0.011 16.2 6.5 0.04 14.4 0.9 2.5 1 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 KIK42366.1 - 0.11 12.4 0.1 0.11 12.4 0.1 3.1 4 0 0 4 4 3 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KIK42366.1 - 0.5 10.2 6.8 8.3 6.3 0.0 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type zf_ZIC PF18366.1 KIK42366.1 - 0.5 10.5 4.7 3.3 7.9 0.0 3.3 1 1 2 3 3 3 0 Zic proteins zinc finger domain zf-LYAR PF08790.11 KIK42366.1 - 0.85 9.6 6.2 3.1 7.8 0.1 3.3 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger IBR PF01485.21 KIK42366.1 - 1.1 9.5 9.8 24 5.2 8.2 2.5 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 KIK42366.1 - 8.8 6.6 12.0 3.2 8.0 4.3 3.1 2 1 1 3 3 3 0 AN1-like Zinc finger Fibrillin_U_N PF18193.1 KIK42369.1 - 0.056 13.6 0.1 0.098 12.8 0.1 1.4 1 0 0 1 1 1 0 Fibrillin 1 unique N-terminal domain Tachystatin_B PF11478.8 KIK42369.1 - 0.32 10.9 2.0 1.6 8.7 2.0 2.0 1 1 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B zf-C2H2 PF00096.26 KIK42372.1 - 2.4e-06 27.7 3.2 0.00023 21.4 0.3 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK42372.1 - 0.0013 19.3 4.1 0.024 15.4 0.2 2.6 2 1 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KIK42372.1 - 0.042 14.5 2.0 3.6 8.3 0.3 2.1 1 1 1 2 2 2 0 FOXP coiled-coil domain Transmemb_17 PF09799.9 KIK42375.1 - 0.012 16.2 2.5 0.012 16.2 2.5 1.8 2 0 0 2 2 2 0 Predicted membrane protein Peptidase_U4 PF03419.13 KIK42375.1 - 8.2 5.6 9.5 37 3.5 0.1 1.6 1 1 1 2 2 2 0 Sporulation factor SpoIIGA KDZ PF18758.1 KIK42376.1 - 4.6e-65 219.4 0.1 7.4e-65 218.7 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK42376.1 - 7.4e-44 148.3 0.0 1.6e-43 147.2 0.0 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK42376.1 - 0.015 15.4 1.3 0.022 14.9 0.0 1.9 2 0 0 2 2 2 0 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK42376.1 - 0.016 15.0 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases Cauli_VI PF01693.16 KIK42377.1 - 0.00018 21.7 0.7 0.00038 20.7 0.7 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin Chromo PF00385.24 KIK42378.1 - 4.2e-05 23.4 0.7 6.3e-05 22.8 0.7 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Phage_X PF05155.15 KIK42378.1 - 0.084 13.3 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Phage X family Cnd3 PF12719.7 KIK42381.1 - 8.8e-87 291.0 2.8 2e-86 289.9 1.1 2.3 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KIK42381.1 - 4.5e-09 36.6 8.4 5.4e-06 26.7 0.2 4.3 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 KIK42381.1 - 7.3e-07 28.9 8.6 0.51 10.7 0.3 5.1 5 0 0 5 5 5 3 HEAT repeat Cnd1 PF12717.7 KIK42381.1 - 0.00012 22.2 6.5 0.05 13.6 0.1 4.4 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KIK42381.1 - 0.0024 18.3 6.7 0.45 11.1 0.3 4.4 4 0 0 4 4 4 2 HEAT-like repeat RTP1_C1 PF10363.9 KIK42381.1 - 0.004 17.3 2.2 0.54 10.5 0.0 4.2 4 1 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KIK42381.1 - 0.0048 16.5 0.2 1.5 8.3 0.0 2.9 3 0 0 3 3 3 1 CLASP N terminal DUF3246 PF11596.8 KIK42381.1 - 0.27 10.6 15.5 0.13 11.7 7.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) DUF1840 PF08895.11 KIK42381.1 - 1.1 9.7 5.6 50 4.3 0.0 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) API5 PF05918.11 KIK42381.1 - 4.7 5.9 9.3 5.2 5.8 0.1 3.3 3 1 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) DTHCT PF08070.11 KIK42381.1 - 9.4 7.0 23.7 0.16 12.7 11.8 3.1 3 0 0 3 3 2 0 DTHCT (NUC029) region FAM199X PF15814.5 KIK42382.1 - 0.017 14.2 2.3 0.04 13.0 2.3 1.5 1 0 0 1 1 1 0 Protein family FAM199X Pkinase PF00069.25 KIK42385.1 - 1.1e-69 234.7 0.0 1.7e-69 234.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK42385.1 - 2.8e-39 134.9 0.0 4.8e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KIK42385.1 - 1.5e-38 130.8 2.6 1e-19 70.5 0.4 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KIK42385.1 - 2.7e-06 26.9 0.0 1.2e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KIK42385.1 - 0.0055 15.7 0.7 0.0083 15.1 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain DUF4520 PF15016.6 KIK42385.1 - 0.017 15.2 0.1 0.05 13.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) FAD_binding_3 PF01494.19 KIK42386.1 - 1.6e-44 152.6 0.0 3.3e-27 95.6 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KIK42386.1 - 2.3e-06 27.0 1.2 0.0027 17.0 0.2 2.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK42386.1 - 3.8e-05 23.1 0.2 0.00016 21.0 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIK42386.1 - 4.2e-05 23.1 0.0 6.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIK42386.1 - 4.5e-05 22.5 0.4 0.16 10.8 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.14 KIK42386.1 - 5.8e-05 22.0 0.1 0.019 13.6 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 KIK42386.1 - 0.00014 21.1 0.7 0.00027 20.2 0.7 1.5 1 1 0 1 1 1 1 FAD binding domain ThiF PF00899.21 KIK42386.1 - 0.0013 18.2 0.1 0.002 17.5 0.1 1.3 1 0 0 1 1 1 1 ThiF family Lycopene_cycl PF05834.12 KIK42386.1 - 0.004 16.3 0.5 3.6 6.5 0.2 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.24 KIK42386.1 - 0.0061 16.2 1.0 0.064 12.8 0.8 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 KIK42386.1 - 0.0068 15.5 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 KIK42386.1 - 0.022 15.0 0.2 0.051 13.8 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIK42386.1 - 0.022 14.0 0.1 0.044 13.0 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.20 KIK42386.1 - 0.034 14.2 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KIK42386.1 - 0.043 14.2 0.0 0.085 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.22 KIK42386.1 - 0.099 11.7 2.5 0.18 10.9 2.5 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A F-box PF00646.33 KIK42388.1 - 0.00043 20.1 0.0 0.0012 18.7 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK42388.1 - 0.0017 18.2 1.4 0.0031 17.4 0.2 2.0 2 0 0 2 2 2 1 F-box-like DUF4881 PF16222.5 KIK42388.1 - 0.0068 16.3 0.1 0.027 14.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4881) RNA_pol_N PF01194.17 KIK42389.1 - 1.8e-32 111.4 0.5 2.1e-32 111.2 0.5 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 KIK42389.1 - 0.056 13.7 0.1 0.069 13.4 0.1 1.2 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Mu-like_Com PF10122.9 KIK42389.1 - 0.071 12.6 0.9 0.42 10.1 0.9 2.0 1 1 0 1 1 1 0 Mu-like prophage protein Com Cnd1 PF12717.7 KIK42390.1 - 1.7e-53 181.0 6.0 2e-50 171.0 0.1 4.0 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 KIK42390.1 - 2.8e-53 180.1 0.0 2.8e-53 180.1 0.0 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.6 KIK42390.1 - 3.2e-07 30.6 0.5 0.27 11.7 0.0 5.9 5 2 0 5 5 5 2 HEAT repeats HEAT PF02985.22 KIK42390.1 - 2.4e-05 24.2 0.2 5.8 7.5 0.1 6.1 6 0 0 6 6 6 1 HEAT repeat Adaptin_N PF01602.20 KIK42390.1 - 0.00084 18.0 4.1 0.02 13.5 0.2 3.8 4 1 0 4 4 4 1 Adaptin N terminal region ENTH PF01417.20 KIK42390.1 - 0.0046 17.0 0.3 5.2 7.1 0.0 3.6 4 0 0 4 4 4 1 ENTH domain Cnd3 PF12719.7 KIK42390.1 - 0.0077 15.5 1.3 0.44 9.7 0.3 3.4 4 0 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain OrfA PF17495.2 KIK42390.1 - 0.018 15.2 0.0 0.047 13.8 0.0 1.7 1 0 0 1 1 1 0 Vpr-like OrfA GCIP PF13324.6 KIK42390.1 - 0.99 9.0 6.4 1.3 8.6 4.7 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting BNIP2 PF12496.8 KIK42390.1 - 2.6 8.5 8.0 0.13 12.7 1.2 2.4 3 0 0 3 3 3 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF2322 PF10084.9 KIK42392.1 - 0.069 13.2 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2322) PIP5K PF01504.18 KIK42394.1 - 3.3e-96 321.7 0.0 6.2e-96 320.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase CHAT PF12770.7 KIK42396.1 - 3.9e-44 151.2 0.0 5e-30 104.9 0.0 2.3 2 0 0 2 2 2 2 CHAT domain TPR_10 PF13374.6 KIK42396.1 - 1.1e-08 34.7 22.0 0.013 15.3 0.1 8.5 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIK42396.1 - 3.9e-07 29.6 7.4 2.7 8.0 0.0 7.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK42396.1 - 8.7e-07 28.6 7.1 1.4 9.2 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK42396.1 - 1.7e-06 28.2 18.2 0.15 12.4 0.2 7.4 6 2 2 8 8 8 3 Tetratricopeptide repeat MIT PF04212.18 KIK42396.1 - 7.5e-06 25.9 0.3 6.2 7.0 0.0 5.0 5 0 0 5 5 5 2 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 KIK42396.1 - 0.00088 19.1 8.3 10 6.4 0.2 6.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK42396.1 - 0.092 13.6 13.3 1e+02 4.1 0.1 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK42396.1 - 0.2 11.4 1.9 47 3.8 0.0 4.2 5 0 0 5 5 5 0 TPR repeat TPR_8 PF13181.6 KIK42396.1 - 0.66 10.3 10.2 21 5.7 0.0 6.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIK42397.1 - 4.4e-11 42.3 16.7 0.004 17.0 0.1 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK42397.1 - 8.1e-08 32.4 12.8 1.5 9.1 0.1 8.0 6 2 3 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK42397.1 - 5.9e-05 22.8 3.2 5 7.4 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK42397.1 - 0.00082 19.1 4.8 11 6.1 0.2 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat MIT PF04212.18 KIK42397.1 - 0.0011 19.0 0.1 1.9 8.6 0.0 4.5 5 0 0 5 5 5 1 MIT (microtubule interacting and transport) domain DUF4404 PF14357.6 KIK42397.1 - 0.0057 17.3 0.2 11 6.7 0.0 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4404) TPR_2 PF07719.17 KIK42397.1 - 0.011 15.7 8.0 21 5.5 0.0 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF3288 PF11691.8 KIK42397.1 - 0.034 14.2 0.1 0.24 11.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3288) SMBP PF16785.5 KIK42397.1 - 0.081 13.2 0.0 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 Small metal-binding protein HEPN_Apea PF18739.1 KIK42397.1 - 0.11 13.0 0.2 8.8 6.8 0.2 3.0 1 1 0 1 1 1 0 Apea-like HEPN TPR_16 PF13432.6 KIK42397.1 - 0.65 10.7 10.6 19 6.0 0.1 5.5 5 1 2 7 7 7 0 Tetratricopeptide repeat DUF4164 PF13747.6 KIK42397.1 - 0.73 10.1 4.5 1e+02 3.2 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4164) Vta1_C PF18097.1 KIK42397.1 - 1.3 8.8 3.1 7.3 6.4 0.0 3.6 3 0 0 3 3 3 0 Vta1 C-terminal domain CRISPR_Cse2 PF09485.10 KIK42397.1 - 2.9 8.4 9.8 0.58 10.7 0.4 3.2 2 1 1 3 3 3 0 CRISPR-associated protein Cse2 (CRISPR_cse2) CHAT PF12770.7 KIK42398.1 - 0.0016 17.9 0.0 0.15 11.5 0.0 2.2 1 1 0 1 1 1 1 CHAT domain E1-E2_ATPase PF00122.20 KIK42401.1 - 1.9e-48 164.4 0.1 1.9e-48 164.4 0.1 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KIK42401.1 - 8.7e-19 68.6 1.8 2.6e-18 67.1 1.8 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KIK42401.1 - 5.1e-12 45.3 0.0 1.3e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KIK42401.1 - 0.00028 20.7 0.0 0.001 18.9 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIK42401.1 - 0.01 15.9 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Asp PF00026.23 KIK42404.1 - 8.5e-46 156.8 15.5 7.7e-45 153.7 15.5 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK42404.1 - 1.6e-06 28.5 6.0 6.4e-05 23.3 0.2 3.4 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KIK42404.1 - 0.19 11.5 2.0 5.1 6.9 0.1 2.6 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal Oxidored_FMN PF00724.20 KIK42407.1 - 1.4e-64 218.5 0.0 2e-64 218.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family 3HCDH_RFF PF18321.1 KIK42407.1 - 0.026 14.9 0.1 0.19 12.2 0.0 2.3 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Dus PF01207.17 KIK42407.1 - 0.052 12.6 0.1 0.11 11.6 0.0 1.5 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Bac_DNA_binding PF00216.21 KIK42407.1 - 0.13 12.5 0.1 0.28 11.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial DNA-binding protein MtN3_slv PF03083.16 KIK42408.1 - 0.078 13.0 0.1 0.22 11.6 0.0 1.7 1 1 1 2 2 2 0 Sugar efflux transporter for intercellular exchange Glyco_transf_20 PF00982.21 KIK42410.1 - 9.4e-140 466.4 0.0 2e-77 260.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KIK42410.1 - 6.6e-69 231.6 0.0 3.2e-68 229.4 0.0 1.9 2 0 0 2 2 2 1 Trehalose-phosphatase CHAT PF12770.7 KIK42411.1 - 6.9e-25 88.0 0.0 8e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 CHAT domain Peptidase_C25 PF01364.18 KIK42411.1 - 0.082 12.1 0.0 0.089 12.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C25 F-box-like PF12937.7 KIK42412.1 - 3.4e-08 33.2 1.8 3.4e-08 33.2 1.8 2.1 2 0 0 2 2 2 1 F-box-like Herpes_heli_pri PF05774.11 KIK42412.1 - 0.13 12.5 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus helicase-primase complex component ABC_tran_CTD PF16326.5 KIK42412.1 - 0.15 12.4 0.1 0.3 11.4 0.1 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain F-box PF00646.33 KIK42412.1 - 0.93 9.4 4.1 11 6.0 0.1 3.4 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 KIK42413.1 - 3e-06 27.0 2.4 3e-06 27.0 2.4 2.0 2 1 0 2 2 2 1 F-box-like Snapin_Pallidin PF14712.6 KIK42413.1 - 0.00063 20.1 1.6 0.00088 19.6 1.6 1.3 1 0 0 1 1 1 1 Snapin/Pallidin Hydin_ADK PF17213.3 KIK42413.1 - 0.0013 19.0 0.5 0.0018 18.6 0.5 1.2 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain NPV_P10 PF05531.12 KIK42413.1 - 0.018 15.5 0.9 0.025 15.0 0.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Ribosomal_S7e PF01251.18 KIK42413.1 - 0.031 14.0 0.2 0.038 13.7 0.2 1.1 1 0 0 1 1 1 0 Ribosomal protein S7e DUF3450 PF11932.8 KIK42413.1 - 0.031 13.6 1.7 0.038 13.3 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2452 PF10504.9 KIK42413.1 - 0.034 13.6 0.7 4.5 6.7 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2452) Vps52 PF04129.12 KIK42413.1 - 0.037 12.8 0.3 0.041 12.6 0.3 1.0 1 0 0 1 1 1 0 Vps52 / Sac2 family Fib_alpha PF08702.10 KIK42413.1 - 0.055 13.7 1.0 0.064 13.4 1.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2205 PF10224.9 KIK42413.1 - 0.061 13.3 2.3 0.088 12.8 2.3 1.3 1 0 0 1 1 1 0 Short coiled-coil protein DivIC PF04977.15 KIK42413.1 - 0.075 12.8 3.1 0.11 12.3 3.1 1.2 1 0 0 1 1 1 0 Septum formation initiator EzrA PF06160.12 KIK42413.1 - 0.094 10.9 0.5 0.11 10.6 0.5 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF1664 PF07889.12 KIK42413.1 - 0.12 12.4 1.7 0.18 11.8 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Prefoldin PF02996.17 KIK42413.1 - 0.2 11.5 1.9 0.32 10.9 1.9 1.2 1 0 0 1 1 1 0 Prefoldin subunit CoA_transf_3 PF02515.17 KIK42415.1 - 1.8e-59 201.7 0.0 4.3e-59 200.5 0.0 1.5 1 1 0 1 1 1 1 CoA-transferase family III Glyco_hydro_79C PF16862.5 KIK42416.1 - 6e-16 59.2 0.6 3.3e-15 56.8 0.1 2.4 2 1 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_79n PF03662.14 KIK42416.1 - 0.058 12.3 0.0 0.27 10.1 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 79, N-terminal domain Glyco_hydro_79C PF16862.5 KIK42417.1 - 6e-17 62.4 0.6 1.8e-16 60.9 0.3 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_79n PF03662.14 KIK42417.1 - 0.053 12.5 0.0 0.12 11.3 0.0 1.7 1 1 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain Med2 PF11214.8 KIK42418.1 - 0.05 13.8 0.0 0.073 13.2 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 2 NIF PF03031.18 KIK42418.1 - 0.14 12.0 0.1 0.48 10.2 0.1 1.8 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase UPF0061 PF02696.14 KIK42421.1 - 3.8e-101 339.2 0.0 8e-101 338.1 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Amnionless PF14828.6 KIK42422.1 - 2.4e-05 23.4 0.0 3.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Amnionless Shisa PF13908.6 KIK42422.1 - 0.0031 17.8 0.1 0.013 15.7 0.1 2.0 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator FAM176 PF14851.6 KIK42422.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 FAM176 family Alpha_GJ PF03229.13 KIK42422.1 - 0.012 16.2 3.6 0.012 16.2 3.6 3.0 2 1 1 3 3 3 0 Alphavirus glycoprotein J TMEM154 PF15102.6 KIK42422.1 - 0.019 14.9 0.1 0.076 12.9 0.1 2.0 1 0 0 1 1 1 0 TMEM154 protein family DAG1 PF05454.11 KIK42422.1 - 0.045 13.1 0.0 0.098 12.0 0.0 1.5 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) EphA2_TM PF14575.6 KIK42422.1 - 0.17 12.8 0.0 0.34 11.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain GST_N_4 PF17172.4 KIK42423.1 - 2.7e-25 89.0 0.0 5.9e-25 87.9 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 KIK42423.1 - 2.2e-10 40.9 0.0 3.4e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 KIK42423.1 - 6.7e-09 35.4 0.0 1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIK42423.1 - 0.00018 21.8 0.0 0.00061 20.2 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK42423.1 - 0.017 15.3 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK42423.1 - 0.04 13.9 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain adh_short PF00106.25 KIK42426.1 - 3.2e-86 287.8 18.7 1.7e-43 148.4 2.5 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK42426.1 - 2.1e-65 220.5 18.1 3.2e-33 115.2 3.4 3.0 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK42426.1 - 1.2e-28 100.2 11.2 9.1e-16 58.3 4.1 2.2 2 0 0 2 2 2 2 KR domain 3HCDH_N PF02737.18 KIK42426.1 - 0.0003 20.7 8.3 0.016 15.1 1.4 2.5 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KIK42426.1 - 0.00045 19.6 3.2 0.047 13.0 1.0 2.8 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 KIK42426.1 - 0.0053 16.8 0.7 0.16 12.0 0.2 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase hnRNP_Q_AcD PF18360.1 KIK42426.1 - 0.16 11.9 0.3 6.5 6.8 0.1 2.4 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain CstA_5TM PF13722.6 KIK42426.1 - 0.23 11.9 1.1 1.5 9.3 0.1 2.4 2 1 0 2 2 2 0 5TM C-terminal transporter carbon starvation CstA PglL_A PF15864.5 KIK42426.1 - 0.29 10.9 6.4 6.4 6.6 0.4 2.5 2 0 0 2 2 2 0 Protein glycosylation ligase DUF543 PF04418.12 KIK42426.1 - 1 9.4 5.8 3.2 7.8 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF543) UDPG_MGDP_dh_N PF03721.14 KIK42426.1 - 1.2 8.7 3.4 5.4 6.5 0.3 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Cyclin_N PF00134.23 KIK42427.1 - 1.1e-41 141.5 0.3 2.6e-41 140.3 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KIK42427.1 - 3.6e-24 85.1 0.1 6.9e-24 84.2 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Glyco_transf_54 PF04666.13 KIK42427.1 - 0.081 11.8 0.5 0.2 10.5 0.5 1.6 2 0 0 2 2 2 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region G-patch PF01585.23 KIK42429.1 - 2.5e-10 40.1 1.6 4.1e-10 39.4 1.6 1.4 1 0 0 1 1 1 1 G-patch domain FHA PF00498.26 KIK42429.1 - 4.4e-06 27.0 0.0 9.6e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 FHA domain G-patch_2 PF12656.7 KIK42429.1 - 0.00052 20.1 0.1 0.00091 19.3 0.1 1.4 1 0 0 1 1 1 1 G-patch domain XLF PF09302.11 KIK42430.1 - 4.4e-05 23.7 1.0 0.0012 19.0 1.0 2.2 1 1 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Acyl-CoA_dh_1 PF00441.24 KIK42435.1 - 6.8e-28 97.8 0.4 1.1e-27 97.2 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIK42435.1 - 4.9e-18 65.1 0.4 9e-18 64.3 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KIK42435.1 - 2.9e-15 56.2 0.0 5.9e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KIK42435.1 - 1e-12 48.7 0.0 2.4e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KIK42435.1 - 0.0031 17.8 0.0 0.0058 16.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Methyltransf_25 PF13649.6 KIK42437.1 - 0.0045 17.7 0.0 0.13 12.9 0.0 2.9 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_2 PF00891.18 KIK42437.1 - 0.059 12.7 0.0 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase domain LysM PF01476.20 KIK42438.1 - 0.0022 18.0 0.0 0.0051 16.9 0.0 1.6 1 0 0 1 1 1 1 LysM domain DUF1292 PF06949.11 KIK42438.1 - 0.6 11.1 3.9 24 6.0 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1292) APG17 PF04108.12 KIK42439.1 - 1.8e-76 257.9 15.2 2.2e-76 257.5 15.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 Spectrin_like PF18373.1 KIK42439.1 - 0.0015 18.5 6.7 0.18 11.9 0.6 3.6 4 0 0 4 4 4 2 Spectrin like domain DUF4043 PF13252.6 KIK42439.1 - 0.096 11.8 0.3 0.26 10.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4043) ExsD PF16806.5 KIK42439.1 - 0.51 10.2 11.1 2.3 8.1 1.5 3.0 2 1 1 3 3 3 0 Antiactivator protein ExsD Exonuc_VII_S PF02609.16 KIK42439.1 - 7.9 6.6 12.5 16 5.6 0.1 5.0 4 1 1 5 5 5 0 Exonuclease VII small subunit MaoC_dehydratas PF01575.19 KIK42441.1 - 2.1e-32 111.3 0.0 3.4e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KIK42441.1 - 3.3e-05 24.0 0.0 0.02 15.0 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Na_Ca_ex PF01699.24 KIK42442.1 - 9.8e-38 129.5 40.2 2.1e-19 70.0 12.3 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein F-box-like PF12937.7 KIK42443.1 - 0.00011 22.1 1.3 0.00083 19.2 1.3 2.4 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIK42443.1 - 0.0038 17.6 0.2 0.56 10.7 0.0 2.9 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) Erg28 PF03694.13 KIK42445.1 - 2.6e-41 140.4 5.1 3.1e-41 140.2 5.1 1.1 1 0 0 1 1 1 1 Erg28 like protein CS PF04969.16 KIK42447.1 - 1.8e-08 35.3 0.0 3.6e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 CS domain Sel1 PF08238.12 KIK42447.1 - 0.24 12.2 0.8 13 6.6 0.0 2.6 2 0 0 2 2 2 0 Sel1 repeat zf-C2HC5 PF06221.13 KIK42448.1 - 3.7e-15 55.7 4.9 6.3e-15 54.9 4.9 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF4407 PF14362.6 KIK42449.1 - 0.032 13.6 0.0 0.032 13.6 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4407) TENA_THI-4 PF03070.16 KIK42449.1 - 0.089 12.6 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 TENA/THI-4/PQQC family HMMR_C PF15908.5 KIK42449.1 - 0.68 10.2 0.0 0.68 10.2 0.0 4.2 4 1 1 5 5 5 0 Hyaluronan mediated motility receptor C-terminal FlxA PF14282.6 KIK42449.1 - 3.4 7.7 9.7 0.49 10.4 0.4 3.4 3 0 0 3 3 3 0 FlxA-like protein Filament PF00038.21 KIK42449.1 - 3.5 7.1 16.7 0.045 13.3 1.3 4.0 5 1 0 5 5 5 0 Intermediate filament protein DUF4618 PF15397.6 KIK42449.1 - 5.9 6.2 13.1 0.35 10.2 2.8 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4618) Retrotran_gag_2 PF14223.6 KIK42451.1 - 1e-11 44.6 0.0 1.6e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type F-box-like PF12937.7 KIK42453.1 - 0.023 14.6 0.2 0.058 13.3 0.2 1.7 1 0 0 1 1 1 0 F-box-like PUF PF00806.19 KIK42455.1 - 5.9e-31 104.4 0.3 4.6e-07 29.2 0.0 5.9 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat PSCyt1 PF07635.11 KIK42455.1 - 0.059 14.0 0.4 0.39 11.4 0.1 2.5 2 0 0 2 2 2 0 Planctomycete cytochrome C dTDP_sugar_isom PF00908.17 KIK42455.1 - 0.18 11.5 0.0 0.46 10.1 0.0 1.6 2 0 0 2 2 2 0 dTDP-4-dehydrorhamnose 3,5-epimerase Fasciclin PF02469.22 KIK42456.1 - 1.2e-05 25.5 0.0 1.9e-05 24.9 0.0 1.3 1 1 0 1 1 1 1 Fasciclin domain F-box-like PF12937.7 KIK42458.1 - 0.0003 20.6 0.0 0.0014 18.5 0.0 2.2 1 0 0 1 1 1 1 F-box-like Complex1_49kDa PF00346.19 KIK42459.1 - 3.9e-122 406.6 0.0 4.9e-122 406.2 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KIK42459.1 - 0.0098 14.8 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase CIMR PF00878.18 KIK42460.1 - 1.7e-11 44.4 0.0 0.00019 21.5 0.0 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 KIK42460.1 - 2.5e-11 43.1 0.0 3.6e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 KIK42460.1 - 1.3e-07 31.7 0.0 1e-06 28.8 0.0 2.0 1 1 0 1 1 1 1 Autophagy-related protein 27 S1FA PF04689.13 KIK42460.1 - 0.34 11.1 1.2 0.6 10.3 1.2 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA Utp14 PF04615.13 KIK42461.1 - 2e-195 651.6 37.9 2e-195 651.6 37.9 2.1 1 1 1 2 2 2 1 Utp14 protein AA_permease_2 PF13520.6 KIK42462.1 - 2.6e-69 234.1 50.6 3.3e-69 233.8 50.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK42462.1 - 1.7e-13 50.0 45.8 2.7e-13 49.4 45.8 1.4 1 1 0 1 1 1 1 Amino acid permease COX6C PF02937.15 KIK42462.1 - 0.27 11.4 2.9 26 5.0 0.0 3.6 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIc WD40 PF00400.32 KIK42463.1 - 1.6e-50 167.9 15.0 6.2e-08 33.2 0.3 9.1 10 0 0 10 10 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42463.1 - 2.9e-19 69.1 0.1 0.0016 18.7 0.0 7.8 2 2 6 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KIK42463.1 - 4.8e-09 36.4 0.1 2.1e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 NACHT domain Ge1_WD40 PF16529.5 KIK42463.1 - 5.3e-09 35.5 0.1 0.0071 15.3 0.0 5.1 2 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KIK42463.1 - 4.7e-07 29.6 0.4 0.0037 16.9 0.9 3.2 1 1 2 3 3 3 3 PQQ-like domain AAA_16 PF13191.6 KIK42463.1 - 1.9e-06 28.4 0.1 3.7e-05 24.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain PD40 PF07676.12 KIK42463.1 - 0.00035 20.4 6.1 21 5.2 0.0 6.3 7 0 0 7 7 6 0 WD40-like Beta Propeller Repeat Parvo_NS1 PF01057.17 KIK42463.1 - 0.0027 16.8 0.0 0.0052 15.9 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 WD40_like PF17005.5 KIK42463.1 - 0.0037 16.6 0.0 12 5.1 0.0 4.1 4 1 1 5 5 5 0 WD40-like domain Nbas_N PF15492.6 KIK42463.1 - 0.0042 16.4 2.9 29 3.9 0.1 5.4 3 3 4 7 7 7 0 Neuroblastoma-amplified sequence, N terminal AAA_30 PF13604.6 KIK42463.1 - 0.0051 16.5 0.0 0.015 15.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIK42463.1 - 0.0094 16.1 0.0 0.12 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain Nup160 PF11715.8 KIK42463.1 - 0.011 14.4 0.0 5 5.7 0.0 3.0 3 0 0 3 3 3 0 Nucleoporin Nup120/160 NB-ARC PF00931.22 KIK42463.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Torsin PF06309.11 KIK42463.1 - 0.024 14.8 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_22 PF13401.6 KIK42463.1 - 0.026 14.8 0.0 0.077 13.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain Frtz PF11768.8 KIK42463.1 - 0.028 12.7 0.0 0.25 9.6 0.0 2.2 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz RNA_helicase PF00910.22 KIK42463.1 - 0.041 14.3 0.0 0.11 12.8 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA PF00004.29 KIK42463.1 - 0.049 14.1 0.0 0.15 12.4 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KIK42463.1 - 0.052 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIK42463.1 - 0.055 13.4 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_PrkA PF08298.11 KIK42463.1 - 0.094 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain APS_kinase PF01583.20 KIK42463.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Cytidylate_kin PF02224.18 KIK42463.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase PRAI PF00697.22 KIK42464.1 - 0.026 14.3 0.4 0.03 14.1 0.4 1.1 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase WW PF00397.26 KIK42465.1 - 1.6 8.9 3.8 6.7 6.9 0.3 2.6 2 0 0 2 2 2 0 WW domain CSTF_C PF14304.6 KIK42466.1 - 3.1e-13 49.1 0.7 1.2e-12 47.2 0.7 2.1 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.6 KIK42466.1 - 2.2e-09 37.7 4.7 3.4e-09 37.0 1.6 2.4 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 TFIIA PF03153.13 KIK42466.1 - 1.5 8.7 10.5 1.8 8.5 10.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glutaredoxin PF00462.24 KIK42468.1 - 2.8e-08 33.8 0.0 4e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin OTT_1508_deam PF14441.6 KIK42468.1 - 0.026 14.5 0.0 0.039 14.0 0.0 1.2 1 0 0 1 1 1 0 OTT_1508-like deaminase NIF3 PF01784.18 KIK42469.1 - 1.5e-65 221.2 0.0 1.8e-65 221.0 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) TPX2 PF06886.11 KIK42470.1 - 1.1e-08 35.1 24.1 1.2e-08 35.1 21.1 2.6 2 0 0 2 2 2 1 Targeting protein for Xklp2 (TPX2) TMEM213 PF15192.6 KIK42472.1 - 0.58 10.2 4.2 0.75 9.8 4.2 1.1 1 0 0 1 1 1 0 TMEM213 family ECH_1 PF00378.20 KIK42473.1 - 1.2e-52 178.7 0.0 1.5e-52 178.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIK42473.1 - 6.2e-28 98.2 0.1 1.1e-27 97.5 0.1 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase LSDAT_euk PF18139.1 KIK42473.1 - 0.024 14.0 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 SLOG in TRPM Carboxyl_trans PF01039.22 KIK42473.1 - 0.092 11.4 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 Carboxyl transferase domain Peptidase_M36 PF02128.15 KIK42475.1 - 0.14 11.2 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Fungalysin metallopeptidase (M36) ASFV_L11L PF05293.11 KIK42478.1 - 0.04 14.2 0.3 0.07 13.5 0.3 1.5 1 1 0 1 1 1 0 African swine fever virus (ASFV) L11L protein Adap_comp_sub PF00928.21 KIK42480.1 - 1.6e-23 83.4 0.0 2.6e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KIK42480.1 - 2e-05 24.5 0.1 3.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 KIK42480.1 - 0.014 15.8 0.2 0.025 15.0 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) S-AdoMet_synt_M PF02772.16 KIK42480.1 - 0.077 13.2 0.1 2.5 8.4 0.0 2.4 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, central domain DUF1464 PF07318.12 KIK42480.1 - 0.11 11.6 0.2 0.17 11.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) ubiquitin PF00240.23 KIK42485.1 - 3.9e-35 119.4 0.5 4.3e-35 119.3 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KIK42485.1 - 9.2e-17 60.6 0.6 1e-16 60.5 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KIK42485.1 - 4.9e-06 26.9 0.1 2e-05 25.0 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 KIK42485.1 - 0.0015 18.5 0.3 1.4 9.0 0.1 2.0 2 0 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 KIK42485.1 - 0.0017 18.2 0.0 0.0019 18.1 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KIK42485.1 - 0.0018 18.6 0.0 0.0021 18.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIK42485.1 - 0.0024 18.0 0.1 0.0054 16.8 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KIK42485.1 - 0.019 15.5 0.1 0.022 15.3 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KIK42485.1 - 0.039 13.8 0.0 0.045 13.6 0.0 1.1 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain HATPase_c PF02518.26 KIK42485.1 - 0.11 13.0 0.1 0.12 12.9 0.1 1.1 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GPI-anchored PF10342.9 KIK42486.1 - 5e-08 33.6 1.0 5e-08 33.6 1.0 2.3 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PAP1 PF08601.10 KIK42486.1 - 3.9 7.1 10.7 4.2 7.0 10.7 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Peptidase_M76 PF09768.9 KIK42487.1 - 6.4e-73 244.1 0.9 7.7e-73 243.9 0.9 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 KIK42487.1 - 0.011 15.5 0.7 0.023 14.5 0.4 1.7 2 0 0 2 2 2 0 SprT-like family Dicty_spore_N PF04562.12 KIK42487.1 - 0.076 13.7 0.1 4.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Dictyostelium spore coat protein, N terminus DUF3684 PF12449.8 KIK42488.1 - 8.8e-209 696.0 0.0 2.7e-207 691.1 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 KIK42488.1 - 0.00094 19.0 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HTH_13 PF11972.8 KIK42488.1 - 0.041 14.0 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 HTH DNA binding domain CHAT PF12770.7 KIK42490.1 - 1.9e-31 109.6 0.1 2.3e-31 109.3 0.1 1.0 1 0 0 1 1 1 1 CHAT domain PfkB PF00294.24 KIK42490.1 - 0.019 14.3 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 pfkB family carbohydrate kinase zf-RVT PF13966.6 KIK42491.1 - 0.023 15.4 3.3 0.023 15.4 3.3 1.6 1 1 1 2 2 2 0 zinc-binding in reverse transcriptase Bunya_NS-S PF01104.17 KIK42494.1 - 0.021 14.6 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-s FAM184 PF15665.5 KIK42498.1 - 0.0046 16.8 4.6 0.0065 16.3 4.6 1.2 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B UPF0242 PF06785.11 KIK42498.1 - 0.0065 16.6 3.2 0.0065 16.6 3.2 1.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus LCD1 PF09798.9 KIK42498.1 - 0.0069 15.0 4.4 0.0089 14.6 4.4 1.1 1 0 0 1 1 1 1 DNA damage checkpoint protein NRBF2 PF08961.10 KIK42498.1 - 0.042 13.5 4.1 0.048 13.3 2.9 1.5 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator zf-C4H2 PF10146.9 KIK42498.1 - 0.061 13.6 4.1 0.072 13.4 4.1 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein DUF2312 PF10073.9 KIK42498.1 - 0.87 9.3 5.5 3.4 7.4 0.6 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) bZIP_1 PF00170.21 KIK42498.1 - 1 9.5 4.8 3 8.0 0.9 2.8 1 1 1 2 2 2 0 bZIP transcription factor DUF2205 PF10224.9 KIK42498.1 - 4.6 7.3 8.4 1.6 8.8 4.6 2.2 2 1 1 3 3 3 0 Short coiled-coil protein Pkinase PF00069.25 KIK42499.1 - 0.003 17.0 0.2 0.0053 16.2 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK42499.1 - 0.019 14.3 0.8 0.032 13.6 0.8 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DDE_3 PF13358.6 KIK42504.1 - 0.0002 21.1 0.0 0.0002 21.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease CxC2 PF18803.1 KIK42505.1 - 3.3e-05 24.0 0.6 7.5e-05 22.8 0.4 1.7 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases DNA_pol_E_B PF04042.16 KIK42507.1 - 1.8e-48 164.7 0.2 2.9e-48 164.0 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KIK42507.1 - 0.093 12.8 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain DUF1128 PF06569.11 KIK42507.1 - 0.12 12.3 0.0 6.8 6.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1128) UPF0183 PF03676.14 KIK42508.1 - 4.1e-61 207.4 0.0 5.1e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) AAA PF00004.29 KIK42509.1 - 0.0011 19.4 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIK42509.1 - 0.0047 16.9 0.0 0.0082 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KIK42509.1 - 0.013 14.7 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 KIK42509.1 - 0.047 14.1 0.0 0.22 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 KIK42509.1 - 0.093 12.5 0.0 0.4 10.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain HAD_2 PF13419.6 KIK42510.1 - 7.2e-11 42.5 0.0 1.4e-10 41.5 0.0 1.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK42510.1 - 9e-10 39.2 0.0 2.9e-09 37.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Globin PF00042.22 KIK42510.1 - 0.0084 16.7 0.0 0.016 15.8 0.0 1.4 1 0 0 1 1 1 1 Globin DUF2608 PF11019.8 KIK42510.1 - 0.0086 15.6 0.1 0.66 9.4 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2608) Hydrolase_like PF13242.6 KIK42510.1 - 0.017 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Ribosomal_L6e PF01159.19 KIK42511.1 - 9.3e-39 132.4 0.5 1.3e-38 131.9 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 KIK42511.1 - 8.1e-06 26.0 0.1 8.1e-06 26.0 0.1 2.3 3 0 0 3 3 3 1 Ribosomal protein L6, N-terminal domain Apt1 PF10351.9 KIK42512.1 - 1.5e-84 284.5 3.1 1.5e-84 284.5 3.1 1.7 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 KIK42512.1 - 3.9e-52 177.7 0.0 6.8e-50 170.3 0.0 2.4 1 1 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 KIK42512.1 - 2.1e-35 122.1 0.0 1e-34 119.9 0.0 2.1 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KIK42512.1 - 5.3e-26 91.4 0.0 1.5e-25 90.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 KIK42512.1 - 5.4e-22 78.5 0.0 3.5e-21 75.8 0.0 2.5 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2985 PF11204.8 KIK42513.1 - 2.4e-28 98.1 2.6 4.7e-28 97.2 2.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Pkinase PF00069.25 KIK42514.1 - 1.2e-34 119.9 0.1 1.3e-34 119.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK42514.1 - 4e-18 65.6 0.1 4.7e-18 65.4 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK42514.1 - 3e-05 23.5 0.0 3.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIK42514.1 - 3.5e-05 22.8 0.0 4.3e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIK42514.1 - 9.9e-05 21.8 0.1 0.00013 21.4 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PCNA_C PF02747.15 KIK42514.1 - 0.11 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, C-terminal domain Pox_ser-thr_kin PF05445.11 KIK42514.1 - 0.12 11.3 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 KIK42514.1 - 0.15 12.0 0.2 0.22 11.4 0.1 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KIK42514.1 - 0.15 11.6 0.1 0.17 11.4 0.1 1.1 1 0 0 1 1 1 0 RIO1 family Meth_synt_2 PF01717.18 KIK42517.1 - 1.8e-149 497.4 0.0 3.2e-145 483.4 0.0 2.6 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KIK42517.1 - 9.6e-116 386.7 0.0 2.5e-109 365.6 0.0 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain ETF PF01012.21 KIK42517.1 - 0.19 11.6 2.5 9.1 6.1 0.1 2.5 1 1 1 2 2 2 0 Electron transfer flavoprotein domain SHOCT PF09851.9 KIK42517.1 - 1.2 9.0 4.0 1.1 9.1 0.8 2.6 3 0 0 3 3 3 0 Short C-terminal domain Pkinase PF00069.25 KIK42518.1 - 3.3e-47 161.1 0.0 4.6e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK42518.1 - 1.5e-24 86.7 0.0 2e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KIK42518.1 - 0.007 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KIK42518.1 - 0.014 15.3 0.0 0.043 13.7 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KIK42518.1 - 0.045 13.1 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADH_N PF08240.12 KIK42519.1 - 4.5e-32 110.2 0.2 7.3e-32 109.5 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK42519.1 - 2.3e-22 79.4 0.0 3.5e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK42519.1 - 7.6e-08 33.5 0.1 1e-06 29.8 0.1 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIK42519.1 - 2.8e-07 30.2 0.1 0.0097 15.4 0.1 2.2 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus Methyltransf_25 PF13649.6 KIK42519.1 - 0.0018 18.9 0.0 0.0034 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AlaDh_PNT_C PF01262.21 KIK42519.1 - 0.0019 17.5 0.4 0.0035 16.7 0.1 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KIK42519.1 - 0.034 13.5 0.0 0.11 11.9 0.0 1.8 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KIK42519.1 - 0.036 13.6 0.1 0.066 12.8 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PrmA PF06325.13 KIK42519.1 - 0.046 13.1 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KIK42519.1 - 0.13 12.9 0.0 0.29 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Myc_N PF01056.18 KIK42521.1 - 0.00071 19.6 7.3 0.00071 19.6 7.3 1.4 1 1 0 1 1 1 1 Myc amino-terminal region BSP_II PF05432.11 KIK42521.1 - 0.43 10.2 12.9 0.66 9.6 12.9 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PAC1 PF16094.5 KIK42521.1 - 1.8 7.7 5.4 3.6 6.7 5.4 1.5 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 GTP_EFTU PF00009.27 KIK42522.1 - 4.4e-48 163.4 0.0 6.9e-48 162.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KIK42522.1 - 1e-15 57.6 0.0 1.6e-14 53.8 0.0 2.6 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 KIK42522.1 - 3.4e-14 52.6 0.0 1.1e-06 28.6 0.0 2.4 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KIK42522.1 - 6.8e-08 32.8 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIK42522.1 - 0.00028 20.9 0.0 0.00068 19.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 KIK42522.1 - 0.082 12.7 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain ICMT PF04140.14 KIK42523.1 - 4.1e-27 94.4 0.5 8e-27 93.5 0.2 1.6 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK42523.1 - 6.8e-13 48.9 0.7 6.8e-13 48.9 0.7 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 KIK42523.1 - 0.00016 21.3 0.3 0.00026 20.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 KIK42523.1 - 0.0031 17.0 0.1 0.0054 16.3 0.1 1.4 1 0 0 1 1 1 1 NnrU protein Ribosomal_L6 PF00347.23 KIK42524.1 - 3.2e-27 95.0 6.7 1.4e-15 57.7 3.8 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Beta_helix PF13229.6 KIK42524.1 - 0.056 13.3 0.9 0.15 11.9 0.7 1.7 1 1 1 2 2 2 0 Right handed beta helix region Herpes_U34 PF04541.13 KIK42524.1 - 0.059 12.6 0.1 0.096 11.9 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus virion protein U34 DUF3858 PF12970.7 KIK42524.1 - 0.16 12.0 0.3 0.35 10.9 0.3 1.5 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3858) CTD_bind PF04818.13 KIK42525.1 - 9.4e-06 26.4 0.0 2e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 KIK42525.1 - 0.0047 17.4 0.1 0.0047 17.4 0.1 3.1 4 1 0 4 4 4 1 Subunit of cleavage factor IA Pcf11 CMD PF02627.20 KIK42525.1 - 0.024 14.7 0.0 0.072 13.2 0.0 1.8 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family PriCT_1 PF08708.11 KIK42525.1 - 0.025 14.3 0.0 0.064 13.0 0.0 1.6 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) Zn-C2H2_12 PF18112.1 KIK42525.1 - 0.027 14.9 1.9 6.7 7.3 0.1 3.0 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_4 PF13894.6 KIK42525.1 - 0.46 11.5 1.6 15 6.8 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger PIN_4 PF13638.6 KIK42526.1 - 1.1e-19 71.1 0.0 1.6e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 PIN domain PIN_12 PF16289.5 KIK42526.1 - 0.0088 16.6 0.0 0.015 15.8 0.0 1.4 1 0 0 1 1 1 1 PIN domain Gly_transf_sug PF04488.15 KIK42527.1 - 2.7e-18 66.4 0.1 4.8e-18 65.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KIK42527.1 - 0.018 14.5 0.1 0.027 13.9 0.1 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 KIK42527.1 - 0.049 12.9 0.1 0.095 12.0 0.1 1.4 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain MFS_1 PF07690.16 KIK42529.1 - 1.2e-34 119.9 15.8 1.4e-32 113.0 11.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK42529.1 - 3.7e-06 26.1 5.1 9.1e-06 24.8 5.0 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_5 PF05631.14 KIK42529.1 - 0.00096 18.2 1.3 0.0024 16.9 0.8 1.6 1 1 0 1 1 1 1 Sugar-tranasporters, 12 TM TruD PF01142.18 KIK42530.1 - 1.1e-74 251.8 0.0 1.2e-70 238.5 0.0 3.3 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) OMPdecase PF00215.24 KIK42531.1 - 3.3e-70 236.2 0.1 4.3e-70 235.8 0.1 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Memo PF01875.17 KIK42531.1 - 0.12 11.5 0.2 0.18 10.9 0.2 1.3 1 0 0 1 1 1 0 Memo-like protein eRF1_1 PF03463.15 KIK42532.1 - 2.8e-48 163.2 0.0 4.3e-48 162.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 KIK42532.1 - 1.4e-22 80.3 0.0 2.6e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 KIK42532.1 - 9.8e-18 64.8 0.0 1.5e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 Thioredoxin PF00085.20 KIK42533.1 - 0.0016 18.4 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 KIK42533.1 - 0.0066 15.4 0.0 0.0077 15.2 0.0 1.3 1 0 0 1 1 1 1 Phosducin DUF4640 PF15480.6 KIK42533.1 - 0.072 12.8 2.2 3.7 7.2 0.7 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4640) FAD_binding_7 PF03441.14 KIK42534.1 - 3.1e-77 258.6 0.5 5.1e-77 257.9 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KIK42534.1 - 3.1e-35 121.6 0.0 5.3e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Adeno_IVa2 PF02456.15 KIK42534.1 - 0.0014 17.5 0.0 0.0022 16.9 0.0 1.2 1 0 0 1 1 1 1 Adenovirus IVa2 protein DUF5127 PF17168.4 KIK42535.1 - 7.8e-83 277.7 5.9 1.3e-82 277.0 5.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIK42535.1 - 8e-77 256.8 1.4 8e-77 256.8 1.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIK42535.1 - 3.1e-66 222.9 5.7 4.1e-66 222.5 1.5 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KIK42535.1 - 1.8e-08 33.8 0.3 1.8e-07 30.6 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) Wtap PF17098.5 KIK42537.1 - 2.9e-19 69.5 6.0 1e-18 67.8 5.9 1.9 1 1 0 1 1 1 1 WTAP/Mum2p family SKA1 PF07160.12 KIK42537.1 - 0.00034 20.5 0.1 0.00034 20.5 0.1 2.2 2 1 0 3 3 3 1 Spindle and kinetochore-associated protein 1 Kinesin_assoc PF16183.5 KIK42537.1 - 0.0068 16.6 1.0 0.02 15.1 0.8 1.7 1 1 1 2 2 2 1 Kinesin-associated HAP1_N PF04849.13 KIK42537.1 - 0.023 13.9 4.1 0.034 13.3 0.8 2.0 2 0 0 2 2 2 0 HAP1 N-terminal conserved region SlyX PF04102.12 KIK42537.1 - 0.025 15.2 5.4 6.9 7.4 0.2 3.4 2 1 1 3 3 3 0 SlyX TMF_DNA_bd PF12329.8 KIK42537.1 - 0.037 14.0 4.3 0.66 10.0 0.1 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Helo_like_N PF17111.5 KIK42537.1 - 0.044 13.1 0.8 0.3 10.4 0.1 2.1 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins FPP PF05911.11 KIK42537.1 - 0.053 11.7 0.8 0.08 11.1 0.8 1.3 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF1664 PF07889.12 KIK42537.1 - 0.092 12.8 0.7 0.28 11.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PKcGMP_CC PF16808.5 KIK42537.1 - 0.13 12.2 7.4 3.2 7.7 0.2 3.3 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Bacillus_HBL PF05791.11 KIK42537.1 - 0.23 11.3 0.3 3.2 7.5 0.1 2.0 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) GAS PF13851.6 KIK42537.1 - 0.42 9.9 4.3 0.21 10.9 0.6 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KIK42537.1 - 0.43 9.4 3.7 0.41 9.5 0.4 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Hemerythrin PF01814.23 KIK42537.1 - 0.48 11.1 6.3 0.7 10.5 0.2 2.6 2 1 0 3 3 3 0 Hemerythrin HHE cation binding domain MCC-bdg_PDZ PF10506.9 KIK42537.1 - 1.2 9.3 3.7 1.1 9.3 0.9 2.2 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome WD40_alt PF14077.6 KIK42537.1 - 1.6 8.6 5.5 14 5.6 0.2 2.9 2 1 1 3 3 3 0 Alternative WD40 repeat motif HIP1_clath_bdg PF16515.5 KIK42537.1 - 2.1 9.0 6.0 1.5 9.5 1.5 2.4 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 baeRF_family12 PF18856.1 KIK42537.1 - 2.8 8.5 5.6 27 5.3 3.6 2.7 2 1 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 DUF4407 PF14362.6 KIK42537.1 - 3.7 6.8 8.0 1.5 8.1 2.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.21 KIK42537.1 - 4.4 7.5 5.7 5.9 7.1 1.3 2.9 2 1 0 2 2 2 0 bZIP transcription factor zf-BED PF02892.15 KIK42538.1 - 0.049 13.7 1.2 0.12 12.4 1.2 1.7 1 1 0 1 1 1 0 BED zinc finger Glyco_hydro_18 PF00704.28 KIK42540.1 - 2.8e-48 165.3 0.0 3.6e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF2087 PF09860.9 KIK42540.1 - 0.12 12.5 1.1 1 9.6 0.2 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2087) Arginase PF00491.21 KIK42545.1 - 8.8e-11 41.8 0.1 1.2e-10 41.4 0.1 1.1 1 0 0 1 1 1 1 Arginase family Na_Ca_ex PF01699.24 KIK42547.1 - 8e-39 133.0 40.2 1.1e-21 77.4 15.9 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Gtr1_RagA PF04670.12 KIK42548.1 - 2.1e-86 289.1 0.0 3.4e-86 288.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KIK42548.1 - 7.7e-09 35.2 0.0 1.4e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KIK42548.1 - 9.8e-09 35.5 0.0 3.2e-08 33.8 0.0 1.9 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KIK42548.1 - 1.6e-08 34.3 0.0 2.7e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KIK42548.1 - 5.6e-06 26.4 0.0 1.4e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 KIK42548.1 - 0.016 15.0 0.0 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.9 KIK42548.1 - 0.023 14.5 0.1 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KIK42548.1 - 0.035 14.0 0.4 3.3 7.6 0.1 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 KIK42548.1 - 0.04 13.6 0.1 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Prefoldin_2 PF01920.20 KIK42548.1 - 0.046 13.7 1.9 3.7 7.5 0.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit SRPRB PF09439.10 KIK42548.1 - 0.076 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit APG6_N PF17675.1 KIK42548.1 - 0.08 13.5 0.1 15 6.2 0.0 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region AAA_18 PF13238.6 KIK42548.1 - 0.16 12.5 0.1 9.1 6.8 0.2 2.7 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.6 KIK42548.1 - 0.18 11.3 0.5 20 4.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KIK42548.1 - 1.3 8.1 5.6 43 3.1 5.6 3.0 1 1 0 1 1 1 0 G-protein alpha subunit DMRL_synthase PF00885.19 KIK42549.1 - 2e-55 186.5 0.0 3.8e-55 185.6 0.0 1.4 1 1 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DUF1349 PF07081.11 KIK42549.1 - 0.049 13.3 0.0 1.9 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1349) SRP40_C PF05022.12 KIK42550.1 - 6e-27 94.3 1.0 1.8e-26 92.8 0.1 2.3 2 0 0 2 2 2 1 SRP40, C-terminal domain SOG2 PF10428.9 KIK42550.1 - 0.25 10.5 34.0 0.35 10.0 34.0 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein ATP_bind_3 PF01171.20 KIK42551.1 - 8.4e-38 129.9 0.0 2.4e-37 128.5 0.0 1.7 2 0 0 2 2 2 1 PP-loop family Abhydrolase_6 PF12697.7 KIK42552.1 - 4.5e-07 30.7 0.1 5.8e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK42552.1 - 1.3e-06 27.9 0.0 2.2e-06 27.1 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK42552.1 - 2.6e-05 24.0 0.0 0.0002 21.1 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KIK42552.1 - 0.00021 21.1 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Peptidase_S9 PF00326.21 KIK42552.1 - 0.028 13.9 0.0 0.85 9.1 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Thioesterase PF00975.20 KIK42552.1 - 0.16 12.1 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain YTH PF04146.15 KIK42554.1 - 1.4e-40 138.9 0.4 5.1e-40 137.1 0.0 2.1 2 0 0 2 2 2 1 YT521-B-like domain UPF0261 PF06792.11 KIK42555.1 - 7.7e-155 515.8 0.9 8.7e-155 515.6 0.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) PEP_hydrolase PF09370.10 KIK42556.1 - 3.8e-131 436.1 0.5 4.3e-131 436.0 0.5 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like WD40 PF00400.32 KIK42557.1 - 3.6e-57 189.0 12.4 2.8e-08 34.3 0.1 8.0 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42557.1 - 3.9e-23 81.6 1.6 7.2e-06 26.2 0.1 6.1 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK42557.1 - 3.7e-10 39.1 1.7 0.2 10.2 0.0 4.9 3 1 1 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KIK42557.1 - 1.6e-05 23.9 1.2 0.29 9.8 0.2 3.3 2 1 1 3 3 3 3 Nup133 N terminal like eIF2A PF08662.11 KIK42557.1 - 3.6e-05 23.7 0.0 0.46 10.3 0.0 2.8 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK42557.1 - 0.00093 18.2 3.0 4.6 6.1 0.0 4.1 2 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KIK42557.1 - 0.0041 15.7 0.2 0.029 12.9 0.1 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain Kinesin PF00225.23 KIK42559.1 - 6.6e-98 327.7 17.9 3.3e-55 187.3 0.0 4.7 4 1 0 4 4 4 3 Kinesin motor domain Microtub_bd PF16796.5 KIK42559.1 - 3e-23 82.4 0.0 1.2e-22 80.4 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding Fib_alpha PF08702.10 KIK42559.1 - 0.0042 17.3 5.4 0.0042 17.3 5.4 12.9 5 3 7 15 15 15 6 Fibrinogen alpha/beta chain family TolA_bind_tri PF16331.5 KIK42559.1 - 0.0045 17.0 5.6 0.0045 17.0 5.6 12.2 11 3 2 13 13 13 3 TolA binding protein trimerisation adh_short_C2 PF13561.6 KIK42560.1 - 2.2e-57 194.3 0.2 3.2e-57 193.8 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK42560.1 - 2.8e-43 147.7 0.2 7.9e-43 146.2 0.2 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KIK42560.1 - 2.4e-10 40.6 0.1 4e-10 39.9 0.1 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIK42560.1 - 7.7e-05 22.0 0.0 0.0001 21.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KIK42560.1 - 0.00013 21.6 0.0 0.00066 19.2 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ThiF PF00899.21 KIK42560.1 - 0.018 14.4 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 ThiF family GATA PF00320.27 KIK42561.1 - 8.7e-15 54.0 4.8 1.8e-14 53.0 4.8 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 KIK42561.1 - 9e-08 32.1 0.0 1.8e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 KIK42561.1 - 8.4e-06 26.0 0.0 1.8e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KIK42561.1 - 0.00056 20.1 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 KIK42561.1 - 0.0046 17.2 0.0 0.0091 16.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_12 PF18095.1 KIK42561.1 - 0.0054 16.4 0.1 0.0099 15.5 0.1 1.4 1 0 0 1 1 1 1 UPF0242 C-terminal PAS-like domain Zn-ribbon_8 PF09723.10 KIK42561.1 - 0.025 14.7 0.2 0.064 13.4 0.2 1.7 1 0 0 1 1 1 0 Zinc ribbon domain PAS_8 PF13188.7 KIK42561.1 - 0.077 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 PAS domain Cas_CXXC_CXXC PF09706.10 KIK42561.1 - 0.32 11.3 2.0 18 5.7 0.1 2.8 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) WD40 PF00400.32 KIK42562.1 - 1.4e-16 60.6 9.5 0.00049 20.9 0.2 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42562.1 - 5.7e-14 52.2 0.3 0.00019 21.7 0.0 4.0 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 KIK42562.1 - 0.0007 18.5 1.0 0.0088 14.8 0.6 2.5 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.11 KIK42562.1 - 0.0071 16.2 0.2 0.49 10.2 0.0 2.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KIK42562.1 - 0.081 11.2 0.0 1.6 7.0 0.0 2.5 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz DASH_Dad3 PF08656.10 KIK42563.1 - 2.7e-21 75.4 0.0 3.4e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 Exc PF07825.11 KIK42565.1 - 0.18 11.8 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Excisionase-like protein HET PF06985.11 KIK42569.1 - 3.8e-26 92.2 0.0 7.6e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Acyl-CoA_dh_1 PF00441.24 KIK42570.1 - 3.1e-40 137.8 0.3 3.1e-40 137.8 0.3 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KIK42570.1 - 6.3e-38 129.9 0.0 1.1e-37 129.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KIK42570.1 - 1.6e-23 82.7 0.0 2.9e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KIK42570.1 - 3.6e-16 59.6 0.5 6.2e-16 58.9 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain AAA_16 PF13191.6 KIK42571.1 - 0.17 12.2 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Lactonase PF10282.9 KIK42572.1 - 0.098 11.9 0.0 0.35 10.1 0.0 1.8 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller CLTH PF10607.9 KIK42573.1 - 1.6e-19 70.2 0.0 3.4e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KIK42573.1 - 2e-07 30.9 1.6 3.6e-07 30.1 1.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 KIK42573.1 - 8.3e-05 22.1 0.2 0.00015 21.2 0.2 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.6 KIK42573.1 - 0.0014 18.9 2.3 0.0025 18.1 2.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-Nse PF11789.8 KIK42573.1 - 0.008 16.0 3.4 0.016 15.0 3.4 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 KIK42573.1 - 0.024 14.6 2.3 0.044 13.8 2.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 KIK42573.1 - 0.06 13.2 4.4 0.11 12.4 4.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK42573.1 - 0.071 13.3 1.4 0.17 12.1 1.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KIK42573.1 - 0.091 12.6 2.1 0.19 11.6 2.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Pellino PF04710.14 KIK42573.1 - 0.11 11.1 0.1 0.16 10.6 0.1 1.2 1 0 0 1 1 1 0 Pellino DUF1610 PF07754.11 KIK42573.1 - 0.16 12.0 0.3 5.7 7.0 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF1610) zf-C3HC4_2 PF13923.6 KIK42573.1 - 0.56 10.1 3.8 1.1 9.2 3.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ORC6 PF05460.13 KIK42574.1 - 0.013 14.8 1.3 0.016 14.5 1.3 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SPOC PF07744.13 KIK42574.1 - 0.036 14.0 0.1 0.044 13.7 0.1 1.2 1 0 0 1 1 1 0 SPOC domain Shisa PF13908.6 KIK42575.1 - 0.18 12.0 0.9 0.19 12.0 0.9 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator AMP-binding PF00501.28 KIK42576.1 - 1e-22 80.4 0.0 1.5e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NPP1 PF05630.11 KIK42576.1 - 0.013 15.6 0.1 0.02 15.0 0.1 1.2 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) Linker_histone PF00538.19 KIK42577.1 - 1.4e-20 73.4 0.0 7e-20 71.2 0.0 2.2 2 2 1 3 3 3 1 linker histone H1 and H5 family DUF883 PF05957.13 KIK42577.1 - 0.76 10.4 5.4 0.26 11.9 2.8 1.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Linker_histone PF00538.19 KIK42579.1 - 4.6e-22 78.2 0.0 1.5e-21 76.6 0.0 1.9 1 0 0 1 1 1 1 linker histone H1 and H5 family HC2 PF07382.11 KIK42579.1 - 8.6 6.4 98.9 1.1 9.3 8.4 2.2 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 zf-C2H2_4 PF13894.6 KIK42582.1 - 0.0063 17.3 0.1 0.015 16.1 0.1 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK42582.1 - 0.011 16.2 0.2 0.025 15.0 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-ribbon_3 PF13248.6 KIK42582.1 - 0.15 11.5 0.1 0.28 10.7 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2_11 PF16622.5 KIK42582.1 - 0.18 11.6 0.1 0.41 10.5 0.1 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type Pkinase PF00069.25 KIK42583.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain FixS PF03597.15 KIK42584.1 - 2 8.2 4.7 0.38 10.5 0.3 2.2 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Xan_ur_permease PF00860.20 KIK42585.1 - 1.1e-30 106.6 23.9 5.8e-29 101.0 23.9 2.4 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 KIK42585.1 - 0.0027 18.1 3.9 0.0027 18.1 3.9 2.7 2 0 0 2 2 2 1 Molybdate transporter of MFS superfamily Phage_GPL PF05926.11 KIK42586.1 - 0.021 14.8 1.2 0.77 9.7 0.1 2.3 2 0 0 2 2 2 0 Phage head completion protein (GPL) DUF2326 PF10088.9 KIK42586.1 - 0.068 12.9 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2326) EPL1 PF10513.9 KIK42587.1 - 8.4e-23 81.5 0.1 2.1e-22 80.2 0.1 1.7 1 0 0 1 1 1 1 Enhancer of polycomb-like DUF2235 PF09994.9 KIK42589.1 - 1.3e-68 231.5 1.2 2.6e-67 227.2 1.2 2.6 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF3421 PF11901.8 KIK42590.1 - 1.3e-12 47.7 0.1 2.2e-12 47.0 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3421) DUF2235 PF09994.9 KIK42593.1 - 5.9e-60 203.1 0.1 9.2e-59 199.1 0.1 2.5 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) TruB_C PF09142.11 KIK42595.1 - 0.058 13.2 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal CbtA PF09490.10 KIK42596.1 - 0.074 12.8 1.4 0.095 12.5 1.4 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) VIT PF08487.10 KIK42599.1 - 8.6e-32 109.7 0.1 1.7e-31 108.7 0.1 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KIK42599.1 - 2.1e-24 86.3 0.0 4.1e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KIK42599.1 - 3.7e-15 56.6 0.0 8.9e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIK42599.1 - 2e-10 41.2 0.1 7.6e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.6 KIK42599.1 - 2.6e-05 24.0 0.0 7.5e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 KIK42599.1 - 4.8e-05 22.9 0.0 0.00012 21.6 0.0 1.6 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF2267 PF10025.9 KIK42599.1 - 0.3 11.4 1.4 1.3 9.3 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) Pkinase PF00069.25 KIK42607.1 - 1.5e-22 80.2 0.0 2.3e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK42607.1 - 5.1e-20 71.8 0.0 9.2e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase MMR_HSR1 PF01926.23 KIK42607.1 - 1.5e-08 34.7 0.0 2.7e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK42607.1 - 1.8e-06 27.5 0.0 2.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 KIK42607.1 - 9e-05 22.7 0.0 0.0075 16.5 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KIK42607.1 - 0.00022 21.7 0.0 0.00032 21.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIK42607.1 - 0.00046 20.1 0.0 0.001 19.0 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KIK42607.1 - 0.0025 17.9 0.9 0.024 14.7 0.3 2.2 1 1 1 2 2 2 1 Dynamin family Ras PF00071.22 KIK42607.1 - 0.004 16.8 0.0 0.0078 15.8 0.0 1.4 1 0 0 1 1 1 1 Ras family IIGP PF05049.13 KIK42607.1 - 0.015 14.3 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 KIK42607.1 - 0.025 15.1 0.0 0.057 13.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Septin PF00735.18 KIK42607.1 - 0.064 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Septin ATP-gua_PtransN PF02807.15 KIK42611.1 - 0.089 13.2 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, N-terminal domain VIT PF08487.10 KIK42612.1 - 3.7e-18 65.8 0.0 9e-18 64.5 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KIK42612.1 - 4.9e-14 52.6 0.0 1.5e-10 41.2 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 KIK42612.1 - 8.1e-08 32.9 0.1 4.7e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KIK42612.1 - 1.5e-07 31.8 0.0 8.1e-07 29.5 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KIK42612.1 - 8.5e-06 25.6 0.0 2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain TipE PF16972.5 KIK42613.1 - 0.99 8.5 3.2 0.36 10.0 0.3 1.7 2 0 0 2 2 2 0 Na+ channel auxiliary subunit TipE MFS_1 PF07690.16 KIK42614.1 - 7.2e-09 35.0 24.5 7.2e-09 35.0 24.5 2.0 2 1 1 3 3 3 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIK42614.1 - 5.3e-06 26.2 4.2 5.3e-06 26.2 4.2 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KIK42615.1 - 1.1e-17 64.1 32.2 1.1e-17 64.1 32.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIK42615.1 - 7.6e-16 58.2 9.7 7.6e-16 58.2 9.7 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 NLE PF08154.12 KIK42616.1 - 1.5e-15 57.5 0.0 3e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 KIK42616.1 - 7.2e-14 52.0 12.4 0.061 14.2 0.0 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.8 KIK42616.1 - 0.0057 15.4 0.5 1.6 7.3 0.0 2.7 1 1 1 3 3 3 2 Nucleoporin Nup120/160 DUF3551 PF12071.8 KIK42622.1 - 0.018 15.1 0.7 0.019 15.0 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3551) VWA_2 PF13519.6 KIK42626.1 - 3.6e-06 27.6 0.0 8.5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KIK42626.1 - 1.3e-05 25.6 0.0 1.7e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain TadE PF07811.12 KIK42627.1 - 0.53 10.6 4.5 1.6 9.1 0.1 2.5 2 0 0 2 2 2 0 TadE-like protein zf-RING_UBOX PF13445.6 KIK42628.1 - 2.8e-07 30.4 7.3 7.7e-06 25.8 4.0 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIK42628.1 - 1.2e-06 28.3 9.0 2.1e-06 27.6 9.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIK42628.1 - 2e-06 27.6 10.0 3.8e-06 26.7 9.3 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KIK42628.1 - 9.8e-06 25.3 7.2 2e-05 24.3 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK42628.1 - 1.1e-05 25.2 8.3 2.2e-05 24.2 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK42628.1 - 2.8e-05 24.3 11.6 5.3e-05 23.5 11.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK42628.1 - 0.00016 21.5 7.0 0.00046 20.0 7.0 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KIK42628.1 - 0.00026 20.5 0.3 0.00037 20.0 0.3 1.3 1 1 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_4 PF15227.6 KIK42628.1 - 0.0082 16.3 13.6 0.013 15.7 10.6 2.8 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING TMF_DNA_bd PF12329.8 KIK42628.1 - 0.0097 15.9 0.7 0.021 14.8 0.4 1.6 1 1 0 1 1 1 1 TATA element modulatory factor 1 DNA binding zf-RING_6 PF14835.6 KIK42628.1 - 0.011 15.6 0.2 0.011 15.6 0.2 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein FYVE PF01363.21 KIK42628.1 - 0.023 14.8 5.5 0.11 12.6 2.1 2.4 1 1 1 2 2 2 0 FYVE zinc finger Transcrip_reg PF01709.20 KIK42628.1 - 0.045 13.2 0.1 0.058 12.8 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator zf-RING_4 PF14570.6 KIK42628.1 - 0.064 13.1 7.7 0.18 11.6 7.7 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KIK42628.1 - 2.9 8.2 9.8 3.2 8.1 8.2 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain DUF5569 PF17729.1 KIK42629.1 - 0.12 12.3 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5569) RCR PF12273.8 KIK42632.1 - 0.0021 18.7 4.1 0.0045 17.6 4.1 1.7 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.6 KIK42632.1 - 0.048 14.5 0.0 0.069 14.0 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SRF-TF PF00319.18 KIK42636.1 - 3.7e-22 77.5 0.0 5.5e-22 77.0 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Cu-oxidase PF00394.22 KIK42637.1 - 7.8e-43 146.3 0.2 1.4e-39 135.7 0.1 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK42637.1 - 1.4e-39 134.9 6.7 2.3e-38 131.0 0.2 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK42637.1 - 1.7e-37 128.1 1.8 6.6e-34 116.5 0.2 3.4 3 0 0 3 3 3 2 Multicopper oxidase Fungal_trans PF04082.18 KIK42639.1 - 1.8e-19 69.8 0.0 3.2e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK42639.1 - 3.1e-05 24.0 14.3 3.1e-05 24.0 14.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zinc_ribbon_12 PF11331.8 KIK42640.1 - 0.0023 17.7 0.1 0.28 11.0 0.0 2.5 2 0 0 2 2 2 1 Probable zinc-ribbon domain Zn_ribbon_SprT PF17283.2 KIK42640.1 - 0.039 13.9 7.0 0.86 9.6 1.6 3.0 2 1 1 3 3 3 0 SprT-like zinc ribbon domain Cytochrom_NNT PF03264.14 KIK42640.1 - 0.046 13.4 0.1 0.046 13.4 0.1 1.6 2 0 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region zf-LSD1 PF06943.12 KIK42640.1 - 0.25 11.2 4.9 1.8 8.5 0.2 2.3 2 0 0 2 2 2 0 LSD1 zinc finger HypA PF01155.19 KIK42640.1 - 0.29 11.1 1.5 1.1 9.2 0.2 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 KIK42640.1 - 0.71 9.5 2.4 17 5.1 0.3 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger GLTP PF08718.11 KIK42641.1 - 3.8e-39 134.3 0.0 4.6e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) DUF4451 PF14616.6 KIK42642.1 - 2.2e-07 31.1 4.8 0.18 12.0 0.0 3.5 2 1 1 3 3 3 3 Domain of unknown function (DUF4451) S8_pro-domain PF16470.5 KIK42642.1 - 0.052 14.3 0.3 45 4.9 0.0 3.8 4 0 0 4 4 4 0 Peptidase S8 pro-domain PHD PF00628.29 KIK42642.1 - 0.84 9.6 5.5 37 4.3 0.1 4.2 4 0 0 4 4 4 0 PHD-finger TSA PF03249.13 KIK42644.1 - 0.053 12.3 0.7 0.1 11.4 0.7 1.4 1 0 0 1 1 1 0 Type specific antigen Surfac_D-trimer PF09006.11 KIK42644.1 - 0.064 13.2 0.6 15 5.6 0.1 3.0 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation zf-CRD PF17979.1 KIK42644.1 - 1.2 9.2 3.8 2.2 8.4 0.8 2.5 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions MEDS PF14417.6 KIK42644.1 - 1.5 8.6 6.9 0.28 11.0 0.9 2.6 2 1 1 3 3 3 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain ATG16 PF08614.11 KIK42645.1 - 2.2e-06 28.0 9.3 2.7e-06 27.7 9.3 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) SHE3 PF17078.5 KIK42645.1 - 2.1e-05 24.4 9.2 3e-05 23.8 9.2 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Spc7 PF08317.11 KIK42645.1 - 0.00047 19.1 10.8 0.00068 18.6 10.8 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 KIK42645.1 - 0.00096 19.7 7.2 0.00096 19.7 7.2 2.1 1 1 1 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 UPF0242 PF06785.11 KIK42645.1 - 0.0016 18.6 14.0 0.002 18.3 13.2 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Vip3A_N PF12495.8 KIK42645.1 - 0.0052 16.7 0.2 0.0058 16.6 0.2 1.2 1 0 0 1 1 1 1 Vegetative insecticide protein 3A N terminal TACC_C PF05010.14 KIK42645.1 - 0.0093 15.8 11.4 0.012 15.4 11.4 1.1 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FAM76 PF16046.5 KIK42645.1 - 0.0099 15.3 3.8 0.012 15.0 3.8 1.1 1 0 0 1 1 1 1 FAM76 protein CENP-F_leu_zip PF10473.9 KIK42645.1 - 0.013 15.6 9.0 0.013 15.6 9.0 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cnn_1N PF07989.11 KIK42645.1 - 0.028 14.6 9.8 26 5.1 9.8 2.7 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 TMF_TATA_bd PF12325.8 KIK42645.1 - 0.08 13.2 13.3 0.1 12.9 10.6 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 KIK42645.1 - 0.083 13.4 18.4 0.03 14.9 13.4 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region SYCE1 PF15233.6 KIK42645.1 - 0.084 12.9 10.6 0.12 12.4 10.6 1.2 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 GAS PF13851.6 KIK42645.1 - 0.1 11.9 13.2 0.24 10.7 12.8 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Uso1_p115_C PF04871.13 KIK42645.1 - 0.13 12.7 15.8 0.056 13.8 11.9 1.9 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Ribosomal_L37 PF08561.10 KIK42645.1 - 0.13 12.8 7.3 0.069 13.7 4.6 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 kleA_kleC PF17383.2 KIK42645.1 - 0.2 12.0 7.2 2 8.8 0.5 2.7 1 1 2 3 3 3 0 Uncharacterized KorC regulated protein A Jnk-SapK_ap_N PF09744.9 KIK42645.1 - 0.29 11.3 14.5 0.7 10.1 10.4 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 SLATT_4 PF18186.1 KIK42645.1 - 0.42 10.3 7.9 5.5 6.6 0.2 2.1 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 CENP-H PF05837.12 KIK42645.1 - 0.52 10.7 13.4 1.8 9.0 13.4 2.0 1 1 0 1 1 1 0 Centromere protein H (CENP-H) FliJ PF02050.16 KIK42645.1 - 0.58 10.4 14.0 1.1 9.5 14.0 1.4 1 1 0 1 1 1 0 Flagellar FliJ protein DUF812 PF05667.11 KIK42645.1 - 0.72 8.7 14.5 3.8 6.3 14.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF948 PF06103.11 KIK42645.1 - 0.76 10.1 5.5 8.9 6.7 1.9 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.8 KIK42645.1 - 1 9.4 15.9 0.22 11.5 7.1 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 KIK42645.1 - 2.6 7.3 11.2 4.2 6.6 11.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 KIK42645.1 - 3.5 6.9 18.1 12 5.2 4.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Mod_r PF07200.13 KIK42645.1 - 3.6 7.7 16.0 9.2 6.4 13.9 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein YabA PF06156.13 KIK42645.1 - 3.9 8.2 9.3 8.4 7.1 7.7 2.2 1 1 1 2 2 2 0 Initiation control protein YabA SseC PF04888.12 KIK42645.1 - 6 6.4 11.2 0.89 9.1 7.4 1.5 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family Spc24 PF08286.11 KIK42645.1 - 6.8 7.0 12.4 1.1e+02 3.2 12.4 2.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 FUSC PF04632.12 KIK42645.1 - 7.4 5.0 7.4 8.3 4.8 7.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMPIT PF07851.13 KIK42645.1 - 9.3 5.4 7.0 12 5.1 7.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein Cu-oxidase PF00394.22 KIK42646.1 - 5.5e-46 156.6 0.1 5.6e-43 146.8 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK42646.1 - 2.4e-36 124.5 4.3 1.2e-34 119.0 0.1 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK42646.1 - 3.4e-36 123.8 4.0 8.7e-36 122.5 0.2 2.7 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KIK42647.1 - 1e-45 155.7 0.0 4.8e-43 147.0 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK42647.1 - 1.4e-36 125.1 0.7 1.2e-35 122.1 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK42647.1 - 1.6e-35 121.9 9.1 4.2e-34 117.2 2.0 3.8 3 1 0 3 3 3 2 Multicopper oxidase Peptidase_M28 PF04389.17 KIK42649.1 - 7.3e-32 110.7 0.0 1.1e-31 110.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIK42649.1 - 0.054 13.2 0.0 0.074 12.7 0.0 1.6 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 SE PF08491.10 KIK42652.1 - 2.2e-60 204.1 0.0 2.9e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KIK42652.1 - 9.8e-08 31.6 0.1 6.2e-07 29.0 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIK42652.1 - 7.3e-07 29.1 0.0 0.0053 16.4 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 KIK42652.1 - 8.1e-05 21.9 0.0 0.013 14.6 0.0 2.3 2 1 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KIK42652.1 - 0.0095 16.1 0.3 0.035 14.4 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KIK42652.1 - 0.01 15.9 0.0 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KIK42652.1 - 0.011 14.9 0.2 0.87 8.6 0.2 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 KIK42652.1 - 0.043 13.0 0.2 0.097 11.9 0.2 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK42652.1 - 0.047 12.9 0.1 0.21 10.8 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Sacchrp_dh_NADP PF03435.18 KIK42652.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GMC_oxred_N PF00732.19 KIK42652.1 - 0.23 10.8 0.1 8.9 5.6 0.0 2.7 3 0 0 3 3 3 0 GMC oxidoreductase TPR_10 PF13374.6 KIK42653.1 - 5.2e-08 32.5 7.2 0.0055 16.5 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK42653.1 - 0.00016 21.9 10.7 2.3 8.6 0.1 5.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK42653.1 - 0.0056 16.7 0.6 38 4.7 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat CHAT PF12770.7 KIK42653.1 - 0.0082 15.6 0.0 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 CHAT domain TPR_8 PF13181.6 KIK42653.1 - 0.036 14.3 0.0 54 4.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat GATase_4 PF13230.6 KIK42653.1 - 0.095 11.6 0.0 3 6.7 0.0 2.1 1 1 1 2 2 2 0 Glutamine amidotransferases class-II dCMP_cyt_deam_1 PF00383.23 KIK42654.1 - 1.3e-15 57.1 0.1 1.6e-15 56.8 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KIK42654.1 - 1.8e-11 44.3 0.1 3e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KIK42654.1 - 0.0023 17.6 0.9 0.68 9.5 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Sortilin-Vps10 PF15902.5 KIK42655.1 - 2.3e-287 952.8 4.1 2.3e-147 491.4 0.1 2.2 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KIK42655.1 - 1.9e-90 301.7 11.2 4.6e-47 160.5 4.0 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KIK42655.1 - 5.6e-10 37.7 40.0 1.4 9.2 0.0 11.9 11 0 0 11 11 11 6 BNR/Asp-box repeat BNR_2 PF13088.6 KIK42655.1 - 1.7e-05 24.3 3.5 0.51 9.6 0.0 6.3 5 4 0 5 5 5 1 BNR repeat-like domain DUF3592 PF12158.8 KIK42655.1 - 0.0012 19.0 0.1 0.45 10.6 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3592) CHB_HEX_C PF03174.13 KIK42655.1 - 0.0037 17.2 3.7 6 6.9 0.0 5.6 5 1 0 5 5 5 1 Chitobiase/beta-hexosaminidase C-terminal domain Fe_dep_repr_C PF02742.15 KIK42655.1 - 0.12 12.4 0.0 0.74 9.9 0.0 2.1 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain BNR_6 PF15899.5 KIK42655.1 - 0.52 10.5 2.1 12 6.3 0.3 4.0 3 0 0 3 3 3 0 BNR-Asp box repeat Transmemb_17 PF09799.9 KIK42656.1 - 0.3 11.7 12.7 0.12 12.9 7.8 2.7 1 1 1 2 2 2 0 Predicted membrane protein SCAMP PF04144.13 KIK42656.1 - 1.7 8.9 12.0 2.9 8.2 12.0 1.4 1 1 0 1 1 1 0 SCAMP family WD40 PF00400.32 KIK42658.1 - 4.3e-05 24.2 0.0 0.00011 22.9 0.0 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42658.1 - 0.097 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Pheromone PF08015.11 KIK42658.1 - 7.4 7.7 7.7 40 5.3 0.1 2.7 2 1 0 2 2 2 0 Fungal mating-type pheromone TMEM154 PF15102.6 KIK42660.1 - 0.00042 20.2 1.5 0.00042 20.2 1.5 2.2 2 0 0 2 2 2 1 TMEM154 protein family Stevor PF17410.2 KIK42660.1 - 0.0049 16.5 0.1 0.008 15.8 0.1 1.2 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame Podoplanin PF05808.11 KIK42660.1 - 0.0066 16.6 0.8 0.0066 16.6 0.8 2.3 2 0 0 2 2 2 1 Podoplanin Glycophorin_A PF01102.18 KIK42660.1 - 0.029 14.6 0.5 0.029 14.6 0.5 2.4 2 0 0 2 2 2 0 Glycophorin A Herpes_gE PF02480.16 KIK42660.1 - 0.12 11.1 0.1 0.21 10.3 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Insulin_TMD PF17870.1 KIK42660.1 - 1.9 8.6 4.1 3.4 7.8 4.1 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EVI2A PF05399.11 KIK42660.1 - 2.2 7.8 7.8 0.095 12.3 1.3 2.1 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) BPD_transp_1 PF00528.22 KIK42660.1 - 7.5 6.2 10.5 2.4e+02 1.3 10.5 2.2 1 1 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component DX PF01666.17 KIK42661.1 - 0.1 13.0 0.1 0.13 12.7 0.1 1.2 1 0 0 1 1 1 0 DX module WD40 PF00400.32 KIK42663.1 - 1e-10 42.0 3.0 0.00037 21.2 0.0 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42663.1 - 2.3e-05 24.6 0.0 0.17 12.2 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK42663.1 - 0.012 14.6 0.0 0.83 8.6 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2512 PF10710.9 KIK42663.1 - 0.51 10.0 3.4 1 9.0 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) zf-C3HC4_3 PF13920.6 KIK42665.1 - 3.1e-07 30.1 11.0 1.6e-06 27.9 11.0 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK42665.1 - 5e-07 29.5 8.2 8.5e-07 28.8 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK42665.1 - 2e-06 27.6 7.2 3.5e-06 26.9 7.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KIK42665.1 - 8.7e-05 22.8 8.8 0.00016 22.0 8.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KIK42665.1 - 9.9e-05 22.3 5.8 9.9e-05 22.3 5.8 2.2 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KIK42665.1 - 0.00023 21.0 10.2 0.0017 18.2 10.3 2.2 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KIK42665.1 - 0.0029 17.4 5.0 0.0029 17.4 5.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK42665.1 - 0.33 11.2 10.0 2.5 8.3 10.3 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF1644 PF07800.12 KIK42665.1 - 0.61 10.1 7.1 5.4 7.0 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) COPIIcoated_ERV PF07970.12 KIK42666.1 - 8.8e-39 133.6 0.6 1.5e-38 132.9 0.6 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KIK42666.1 - 1.4e-21 76.7 0.0 3e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Maf PF02545.14 KIK42667.1 - 1.5e-42 145.3 0.0 1.8e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein F-box-like PF12937.7 KIK42668.1 - 2.7e-07 30.4 2.6 6.4e-07 29.2 0.3 2.6 2 1 0 2 2 2 1 F-box-like Na_sulph_symp PF00939.19 KIK42671.1 - 5.9e-34 117.9 34.0 7.8e-34 117.5 34.0 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.19 KIK42671.1 - 4.3e-32 112.5 4.2 3.9e-24 86.3 0.2 2.3 1 1 1 2 2 2 2 SPX domain CitMHS PF03600.16 KIK42671.1 - 8.3e-23 81.0 48.4 7.3e-19 68.1 19.4 2.6 2 1 1 3 3 3 2 Citrate transporter PGA2 PF07543.12 KIK42671.1 - 0.0055 16.7 0.5 0.011 15.7 0.5 1.4 1 0 0 1 1 1 1 Protein trafficking PGA2 PBP1_TM PF14812.6 KIK42671.1 - 0.1 13.0 1.2 0.28 11.6 1.2 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.11 KIK42671.1 - 0.13 10.3 0.8 0.24 9.5 0.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Orn_Arg_deC_N PF02784.16 KIK42673.1 - 7.9e-75 251.4 0.0 1e-74 251.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KIK42673.1 - 3.4e-17 62.5 0.0 4.1e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 KIK42673.1 - 0.099 12.1 0.0 0.43 10.0 0.0 1.9 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel PTPA PF03095.15 KIK42674.1 - 4.2e-99 331.8 0.0 4.9e-99 331.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Ku PF02735.16 KIK42675.1 - 1.4e-31 109.8 0.0 7.6e-31 107.4 0.0 2.3 3 1 0 3 3 3 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KIK42675.1 - 9.5e-22 77.8 0.0 1.5e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KIK42675.1 - 1.9e-16 60.5 0.6 5.1e-16 59.1 0.2 1.9 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KIK42675.1 - 9.3e-09 34.8 0.1 2.1e-08 33.7 0.1 1.7 1 0 0 1 1 1 1 SAP domain VWA_2 PF13519.6 KIK42675.1 - 0.0017 19.0 0.0 0.019 15.6 0.0 2.4 1 1 0 1 1 1 1 von Willebrand factor type A domain HeH PF12949.7 KIK42675.1 - 0.06 13.1 0.3 0.17 11.6 0.3 1.9 1 1 0 1 1 1 0 HeH/LEM domain Eco57I PF07669.11 KIK42675.1 - 0.076 13.5 0.1 14 6.3 0.0 2.8 3 0 0 3 3 3 0 Eco57I restriction-modification methylase VWA PF00092.28 KIK42675.1 - 0.12 12.7 0.0 0.76 10.0 0.0 2.1 1 1 0 1 1 1 0 von Willebrand factor type A domain Glutaredoxin PF00462.24 KIK42676.1 - 6e-18 64.8 0.0 2.5e-16 59.6 0.0 2.4 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 KIK42676.1 - 8.7e-11 41.7 0.0 2.3e-10 40.4 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 KIK42676.1 - 0.00073 19.8 0.0 0.21 11.9 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like HyaE PF07449.11 KIK42676.1 - 0.002 18.1 0.0 0.095 12.7 0.0 2.5 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Phosducin PF02114.16 KIK42676.1 - 0.0073 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Phosducin Thioredoxin_2 PF13098.6 KIK42676.1 - 0.0098 16.3 0.0 0.12 12.8 0.0 2.5 2 1 0 2 2 2 1 Thioredoxin-like domain GST_N_3 PF13417.6 KIK42676.1 - 0.13 12.7 0.0 0.56 10.7 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Isochorismatase PF00857.20 KIK42678.1 - 0.00027 21.2 0.1 0.00027 21.2 0.1 1.2 1 0 0 1 1 1 1 Isochorismatase family Chal_sti_synt_C PF02797.15 KIK42678.1 - 0.11 12.5 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain UPF0086 PF01868.16 KIK42679.1 - 7.9e-30 102.6 0.0 1.3e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Mito_carr PF00153.27 KIK42680.1 - 1.7e-55 184.9 3.5 2.2e-23 82.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Hepsin-SRCR PF09272.10 KIK42685.1 - 0.029 14.9 0.1 0.031 14.8 0.1 1.1 1 0 0 1 1 1 0 Hepsin, SRCR domain PH PF00169.29 KIK42686.1 - 0.00024 21.6 0.0 0.00046 20.7 0.0 1.5 1 0 0 1 1 1 1 PH domain CAF1A PF12253.8 KIK42686.1 - 0.23 11.6 10.9 0.73 10.1 10.9 1.9 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Pho88 PF10032.9 KIK42687.1 - 1.1e-74 249.7 0.1 1.2e-74 249.5 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) BH4 PF02180.17 KIK42687.1 - 1.6 8.6 3.6 3.1 7.7 2.4 2.1 2 0 0 2 2 2 0 Bcl-2 homology region 4 ATP-synt_G PF04718.15 KIK42688.1 - 3.5e-14 53.5 0.7 7.8e-14 52.3 0.1 1.8 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit TPR_10 PF13374.6 KIK42690.1 - 5.9e-07 29.2 2.2 0.00025 20.8 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK42690.1 - 0.0051 17.1 5.2 0.039 14.2 2.4 2.8 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK42690.1 - 0.018 14.8 2.2 0.48 10.3 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK42690.1 - 0.052 14.4 4.3 1.1 10.3 0.3 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK42690.1 - 0.71 10.1 3.4 19 5.7 0.2 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK42690.1 - 0.98 9.6 4.1 2.7 8.2 0.2 3.2 2 2 1 3 3 3 0 Tetratricopeptide repeat Glycos_transf_N PF04413.16 KIK42692.1 - 0.17 11.5 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) HEAT PF02985.22 KIK42693.1 - 1.7e-06 27.8 0.3 0.11 12.8 0.0 2.9 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.6 KIK42693.1 - 3.4e-05 24.1 0.8 0.0031 17.9 0.4 2.1 1 1 0 2 2 2 2 HEAT repeats Cohesin_HEAT PF12765.7 KIK42693.1 - 1.3 9.4 5.1 3 8.2 0.1 3.0 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Plavaka PF18759.1 KIK42695.1 - 5e-36 124.5 0.0 8.7e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase DUF916 PF06030.12 KIK42695.1 - 0.084 12.9 0.2 0.17 11.9 0.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) PDDEXK_1 PF12705.7 KIK42695.1 - 0.11 12.3 0.3 0.29 11.0 0.1 1.7 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily ADH_N PF08240.12 KIK42696.1 - 3.3e-28 97.7 1.9 6.5e-28 96.8 1.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK42696.1 - 3.4e-27 95.0 0.5 5.3e-27 94.4 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK42696.1 - 0.00011 23.3 0.1 0.00017 22.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KIK42696.1 - 0.059 12.8 1.2 0.32 10.4 0.5 2.6 3 1 0 3 3 3 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 KIK42696.1 - 0.079 12.2 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain p450 PF00067.22 KIK42697.1 - 2.4e-67 227.7 0.0 3.3e-67 227.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ovate PF04844.13 KIK42697.1 - 0.016 15.2 0.9 0.036 14.1 0.9 1.5 1 0 0 1 1 1 0 Transcriptional repressor, ovate Trp_dioxygenase PF03301.13 KIK42697.1 - 0.09 12.1 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Tryptophan 2,3-dioxygenase Gpi16 PF04113.14 KIK42698.1 - 2.8e-128 428.8 1.8 2.5e-127 425.7 1.8 1.9 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Methyltransf_25 PF13649.6 KIK42699.1 - 0.0045 17.7 0.0 0.45 11.3 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain SWIRM PF04433.17 KIK42701.1 - 1.7e-32 111.6 0.1 2e-31 108.2 0.0 2.3 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KIK42701.1 - 2.3e-19 69.1 9.5 4.3e-19 68.3 9.5 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KIK42701.1 - 1.3e-09 38.1 0.0 2.4e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KIK42701.1 - 2.3e-08 33.7 1.7 3.7e-08 33.0 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 KIK42701.1 - 1.2e-07 31.8 0.0 2.4e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 KIK42701.1 - 0.18 12.0 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 DUF4428 PF14471.6 KIK42701.1 - 0.3 11.0 1.2 0.65 10.0 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Glyco_transf_15 PF01793.16 KIK42702.1 - 1.2e-124 415.8 6.5 1.5e-124 415.5 6.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PPR PF01535.20 KIK42703.1 - 2.1e-05 24.4 0.0 0.8 10.1 0.0 5.0 6 0 0 6 6 6 2 PPR repeat Thioredoxin_14 PF18402.1 KIK42703.1 - 0.0063 16.5 0.1 0.014 15.4 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain PPR_2 PF13041.6 KIK42703.1 - 0.032 14.4 0.0 0.82 9.9 0.0 3.2 4 0 0 4 4 4 0 PPR repeat family Trans_reg_C PF00486.28 KIK42703.1 - 0.097 12.8 0.6 45 4.2 0.0 3.6 2 1 1 3 3 3 0 Transcriptional regulatory protein, C terminal Arm-DNA-bind_5 PF17293.2 KIK42703.1 - 0.12 12.8 0.1 2.1 8.8 0.1 2.5 1 1 1 2 2 2 0 Arm DNA-binding domain PaaB PF06243.11 KIK42703.1 - 0.16 12.2 0.5 16 5.8 0.0 2.5 2 0 0 2 2 2 0 Phenylacetic acid degradation B MFS_1 PF07690.16 KIK42704.1 - 2.4e-11 43.1 41.1 2.4e-11 43.1 41.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily SKG6 PF08693.10 KIK42705.1 - 0.02 14.3 0.9 0.04 13.3 0.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PTP_tm PF18861.1 KIK42705.1 - 0.067 13.2 0.2 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Pkinase PF00069.25 KIK42706.1 - 1.1e-64 218.4 0.0 2.1e-64 217.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK42706.1 - 1.5e-31 109.7 0.0 2.4e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 KIK42706.1 - 0.0002 21.0 0.1 0.081 12.6 0.0 2.3 2 0 0 2 2 2 2 Fungal kinase associated-1 domain APH PF01636.23 KIK42706.1 - 0.0022 18.0 0.0 0.0066 16.4 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family zf-C3HC4_3 PF13920.6 KIK42707.1 - 1.5e-11 44.0 5.7 1.3e-09 37.8 1.5 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK42707.1 - 0.00093 19.0 9.5 0.0011 18.8 5.1 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KIK42707.1 - 0.0017 18.7 6.9 0.0046 17.3 2.1 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KIK42707.1 - 0.006 16.5 3.0 0.053 13.5 1.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain DUF5115 PF17142.4 KIK42707.1 - 0.11 12.1 0.3 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5115) zf-RING_UBOX PF13445.6 KIK42707.1 - 6 7.0 6.6 33 4.6 1.6 2.7 2 0 0 2 2 2 0 RING-type zinc-finger Ribosomal_L27A PF00828.19 KIK42708.1 - 3.6e-22 79.4 0.1 5.2e-22 78.9 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RNA_pol_L_2 PF13656.6 KIK42709.1 - 4.6e-26 90.4 0.0 6.1e-26 90.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KIK42709.1 - 2.2e-11 43.0 0.0 3.9e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain MMR_HSR1 PF01926.23 KIK42710.1 - 2.3e-11 43.8 0.0 5.5e-11 42.6 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK42710.1 - 0.00024 21.1 0.0 0.00062 19.7 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KIK42710.1 - 0.0055 16.3 0.1 0.013 15.0 0.2 1.5 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 KIK42710.1 - 0.013 15.9 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 KIK42710.1 - 0.033 13.7 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family MCM PF00493.23 KIK42710.1 - 0.039 13.0 0.1 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 MCM P-loop domain Septin PF00735.18 KIK42710.1 - 0.049 12.9 0.0 0.073 12.3 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_18 PF13238.6 KIK42710.1 - 0.056 14.0 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KIK42710.1 - 0.068 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 KIK42710.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 KIK42710.1 - 0.18 11.8 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 Dynamin family GTP_EFTU PF00009.27 KIK42710.1 - 0.2 11.2 0.0 4.8 6.7 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain TPPII_N PF12583.8 KIK42711.1 - 0.11 13.1 0.1 0.19 12.3 0.1 1.3 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal RRM_1 PF00076.22 KIK42712.1 - 4.9e-14 51.9 0.0 9.2e-14 51.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KIK42712.1 - 0.048 14.2 1.4 0.048 14.2 1.4 1.7 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 HLH PF00010.26 KIK42713.1 - 2.1e-08 34.0 0.0 5.4e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Abhydrolase_9 PF10081.9 KIK42713.1 - 0.041 13.0 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta-hydrolase family PKcGMP_CC PF16808.5 KIK42713.1 - 0.14 12.0 0.3 0.28 11.1 0.3 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SH PF01445.17 KIK42714.1 - 0.048 13.6 0.5 3.2 7.8 0.0 3.1 3 0 0 3 3 3 0 Viral small hydrophobic protein L6_membrane PF05805.12 KIK42714.1 - 0.075 12.6 0.1 0.075 12.6 0.1 1.4 2 0 0 2 2 2 0 L6 membrane protein 6PF2K PF01591.18 KIK42715.1 - 2.4e-62 210.2 0.0 3.9e-62 209.5 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KIK42715.1 - 1.6e-23 83.4 0.2 1.8e-18 66.9 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KIK42715.1 - 7.2e-06 26.2 0.0 1.8e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KIK42715.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.20 KIK42715.1 - 0.066 13.1 0.1 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase HTH_Tnp_Tc5 PF03221.16 KIK42716.1 - 0.069 13.2 0.3 0.15 12.1 0.1 1.6 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain TIP41 PF04176.13 KIK42716.1 - 0.077 12.5 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 TIP41-like family DUF155 PF02582.14 KIK42717.1 - 1.1e-45 155.8 0.0 1.8e-45 155.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 MPTase-PolyVal PF18818.1 KIK42717.1 - 0.11 12.6 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Metallopeptidase superfamily domain UPF0449 PF15136.6 KIK42717.1 - 0.12 12.8 0.0 1.2 9.7 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 MFS_1 PF07690.16 KIK42718.1 - 4.6e-44 150.8 18.7 1.3e-43 149.4 17.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK42718.1 - 8.1e-13 48.0 19.5 9.6e-13 47.8 3.0 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 KIK42718.1 - 0.0048 15.3 4.1 0.016 13.6 1.4 2.6 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family EptA_B_N PF08019.12 KIK42718.1 - 2.7 7.9 7.7 0.98 9.3 0.3 3.5 3 1 1 4 4 4 0 Phosphoethanolamine transferase EptA/EptB TPT PF03151.16 KIK42722.1 - 8.3e-18 64.7 12.0 9.5e-18 64.5 12.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF1118 PF06549.12 KIK42722.1 - 0.18 12.2 3.8 0.26 11.6 3.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1118) LSM PF01423.22 KIK42723.1 - 3.9e-16 58.5 0.3 5.2e-16 58.1 0.3 1.2 1 0 0 1 1 1 1 LSM domain Phage_Arf PF17585.2 KIK42723.1 - 0.12 12.4 0.1 0.12 12.4 0.1 1.5 2 0 0 2 2 2 0 Accessory recombination function protein GST_C PF00043.25 KIK42724.1 - 4.9e-11 42.7 0.0 7.5e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK42724.1 - 1.1e-10 41.6 0.0 1.9e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KIK42724.1 - 1.3e-09 38.2 0.0 2.2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK42724.1 - 8.8e-09 35.3 0.1 1.4e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIK42724.1 - 0.00078 19.8 0.0 0.0018 18.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Atg8 PF02991.16 KIK42724.1 - 0.041 14.1 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like GST_N_2 PF13409.6 KIK42724.1 - 0.071 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain F-box-like PF12937.7 KIK42725.1 - 2.6e-06 27.2 2.5 2.6e-06 27.2 2.5 2.4 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIK42725.1 - 0.15 12.0 1.1 3.8 7.5 0.1 2.5 2 0 0 2 2 2 0 F-box domain MRF_C1 PF13887.6 KIK42726.1 - 0.019 14.1 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 DUF5516 PF17637.2 KIK42727.1 - 3.7 7.4 5.6 5.3 6.9 2.7 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5516) Fungal_trans PF04082.18 KIK42731.1 - 1.9e-12 46.8 1.4 3e-12 46.2 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK42731.1 - 0.0097 16.0 5.5 0.018 15.1 5.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Serglycin PF04360.12 KIK42731.1 - 0.046 13.7 0.9 0.46 10.4 1.6 2.3 2 0 0 2 2 2 0 Serglycin Bystin PF05291.11 KIK42739.1 - 2.8e-122 407.6 0.0 3.8e-122 407.1 0.0 1.2 1 0 0 1 1 1 1 Bystin Cwf_Cwc_15 PF04889.12 KIK42739.1 - 0.11 12.2 18.0 0.16 11.7 18.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KIK42739.1 - 0.75 7.9 12.8 1 7.5 12.8 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KIK42739.1 - 2.8 7.2 13.3 3.4 6.9 13.3 1.1 1 0 0 1 1 1 0 BUD22 DUF2722 PF10846.8 KIK42739.1 - 4.8 6.0 10.0 6.8 5.5 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) NOA36 PF06524.12 KIK42739.1 - 6 6.1 14.7 11 5.3 14.7 1.4 1 0 0 1 1 1 0 NOA36 protein GDP_Man_Dehyd PF16363.5 KIK42740.1 - 3.5e-61 207.4 0.0 4.3e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIK42740.1 - 2.9e-47 161.2 0.0 4e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK42740.1 - 2.9e-09 36.3 0.0 4.1e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIK42740.1 - 9.3e-07 28.3 0.0 0.0076 15.5 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KIK42740.1 - 4.2e-06 26.1 0.0 5.7e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KIK42740.1 - 8.3e-06 25.1 0.2 0.0039 16.4 0.1 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein Abhydrolase_6 PF12697.7 KIK42741.1 - 5.5e-06 27.1 0.6 8.2e-06 26.6 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK42741.1 - 6e-06 26.1 0.0 0.00024 20.8 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KIK42741.1 - 0.085 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein DUF2458 PF10454.9 KIK42742.1 - 2.1e-09 37.3 0.7 3.1e-09 36.7 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) DGCR6 PF07324.11 KIK42742.1 - 0.0008 19.1 1.4 0.0018 17.9 1.4 1.6 1 1 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein ALIX_LYPXL_bnd PF13949.6 KIK42742.1 - 0.017 14.4 0.4 0.021 14.1 0.4 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV RGS PF00615.19 KIK42744.1 - 1.3e-31 109.3 0.1 6.5e-31 107.1 0.1 2.2 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 KIK42744.1 - 2.4e-14 53.2 0.0 5.6e-08 32.7 0.0 3.4 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) HTH_45 PF14947.6 KIK42744.1 - 0.042 13.8 0.1 1.3 9.1 0.0 3.0 3 0 0 3 3 3 0 Winged helix-turn-helix Cyt-b5 PF00173.28 KIK42745.1 - 4.6e-08 33.1 0.2 9.1e-08 32.1 0.2 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Presenilin PF01080.17 KIK42745.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Presenilin Nup160 PF11715.8 KIK42747.1 - 7.1e-32 110.8 0.0 1.6e-31 109.6 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KIK42747.1 - 0.075 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like PUF PF00806.19 KIK42748.1 - 8.9e-19 66.0 0.0 0.0032 17.1 0.0 7.9 8 0 0 8 8 8 6 Pumilio-family RNA binding repeat ACC_epsilon PF13822.6 KIK42748.1 - 0.8 10.4 3.2 1.1e+02 3.6 0.0 3.8 3 0 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit zn-ribbon_14 PF16503.5 KIK42749.1 - 6.2e-17 60.8 8.4 2.7e-16 58.8 4.7 3.0 3 0 0 3 3 3 1 Zinc-ribbon ATP_bind_3 PF01171.20 KIK42749.1 - 4.2e-09 36.4 0.0 7e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 PP-loop family RecR PF02132.15 KIK42749.1 - 0.0006 19.3 1.4 0.0006 19.3 1.4 2.2 2 0 0 2 2 2 1 RecR protein CTU2 PF10288.9 KIK42749.1 - 0.025 14.8 0.1 0.32 11.3 0.1 2.2 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Whib PF02467.16 KIK42749.1 - 0.071 13.7 1.3 0.12 13.0 0.3 1.8 2 0 0 2 2 2 0 Transcription factor WhiB HIPIP PF01355.17 KIK42749.1 - 0.12 12.7 1.5 3.4 8.1 1.0 2.5 2 0 0 2 2 2 0 High potential iron-sulfur protein adh_short PF00106.25 KIK42750.1 - 4.6e-05 23.0 0.2 0.15 11.5 0.1 2.6 2 1 1 3 3 3 2 short chain dehydrogenase Nop PF01798.18 KIK42751.1 - 1.1e-84 283.6 0.1 1.1e-84 283.6 0.1 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KIK42751.1 - 1.6e-20 73.2 0.8 1.6e-20 73.2 0.8 3.0 3 0 0 3 3 3 1 NOP5NT (NUC127) domain Vfa1 PF08432.10 KIK42751.1 - 0.038 14.3 11.9 0.074 13.4 11.9 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nucleo_P87 PF07267.11 KIK42751.1 - 0.54 9.0 11.5 0.85 8.4 11.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Rtf2 PF04641.12 KIK42751.1 - 2.3 7.5 13.9 4.2 6.7 13.9 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger FAM176 PF14851.6 KIK42751.1 - 6.1 6.5 8.6 18 5.0 8.6 1.8 1 0 0 1 1 1 0 FAM176 family Peptidase_S10 PF00450.22 KIK42752.1 - 1.1e-102 344.6 0.0 1.3e-102 344.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Ferritin_2 PF13668.6 KIK42753.1 - 1.1e-30 106.6 4.4 2e-30 105.8 4.4 1.4 1 0 0 1 1 1 1 Ferritin-like domain EAF PF09816.9 KIK42754.1 - 9.9e-20 70.8 0.0 1.8e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor CCDC53 PF10152.9 KIK42754.1 - 9.7 6.6 10.5 77 3.7 10.5 2.3 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Peptidase_M22 PF00814.25 KIK42759.1 - 3e-72 243.6 0.1 3.5e-72 243.4 0.1 1.0 1 0 0 1 1 1 1 Glycoprotease family BcrAD_BadFG PF01869.20 KIK42759.1 - 0.057 12.9 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Carbam_trans_N PF02543.15 KIK42759.1 - 0.17 11.5 0.1 1.1 8.8 0.1 2.2 2 1 0 2 2 2 0 Carbamoyltransferase N-terminus Ribosomal_S7 PF00177.21 KIK42760.1 - 3.2e-24 85.3 0.4 3.7e-24 85.1 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e COG6 PF06419.11 KIK42762.1 - 0.0062 14.8 4.8 0.0062 14.8 4.8 2.7 1 1 2 3 3 3 1 Conserved oligomeric complex COG6 NRBF2 PF08961.10 KIK42762.1 - 0.0065 16.1 21.5 0.07 12.7 0.9 3.5 1 1 2 3 3 3 2 Nuclear receptor-binding factor 2, autophagy regulator YabA PF06156.13 KIK42762.1 - 0.029 15.0 6.0 0.029 15.0 6.0 3.9 2 1 2 4 4 4 0 Initiation control protein YabA Sec34 PF04136.15 KIK42762.1 - 0.048 13.5 10.3 0.48 10.3 1.2 2.9 2 1 1 3 3 2 0 Sec34-like family ZapB PF06005.12 KIK42762.1 - 0.057 13.9 1.5 0.057 13.9 1.5 3.8 1 1 2 3 3 3 0 Cell division protein ZapB HALZ PF02183.18 KIK42762.1 - 0.065 13.5 8.7 1.1 9.5 0.5 4.3 1 1 5 6 6 6 0 Homeobox associated leucine zipper Rootletin PF15035.6 KIK42762.1 - 0.12 12.4 22.6 2 8.4 10.4 2.5 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion APG6_N PF17675.1 KIK42762.1 - 0.12 12.9 17.5 5.1 7.6 17.5 2.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Ribosomal_S6 PF01250.17 KIK42762.1 - 0.16 12.2 3.8 11 6.4 0.4 3.1 1 1 1 2 2 2 0 Ribosomal protein S6 Cauli_DNA-bind PF03310.13 KIK42762.1 - 0.18 11.9 9.6 0.63 10.1 0.4 3.4 1 1 2 3 3 3 0 Caulimovirus DNA-binding protein DUF3450 PF11932.8 KIK42762.1 - 0.29 10.4 15.6 0.047 13.0 6.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FliL PF03748.14 KIK42762.1 - 0.31 11.7 5.7 2.5 8.7 0.0 2.7 2 1 0 2 2 2 0 Flagellar basal body-associated protein FliL OmpH PF03938.14 KIK42762.1 - 0.34 11.3 10.0 1.1 9.6 1.8 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) GIT_CC PF16559.5 KIK42762.1 - 0.34 10.8 13.6 2.9 7.8 0.3 3.6 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor UPF0242 PF06785.11 KIK42762.1 - 0.34 11.0 21.3 0.2 11.7 11.8 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus pXO2-34 PF17362.2 KIK42762.1 - 0.4 10.6 2.4 39 4.2 0.0 3.3 1 1 2 3 3 3 0 Family of unknown function Cep57_CLD_2 PF14197.6 KIK42762.1 - 0.46 10.6 20.0 0.57 10.3 4.7 2.8 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Uso1_p115_C PF04871.13 KIK42762.1 - 0.51 10.7 15.5 1.2 9.5 4.4 2.6 1 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region THOC7 PF05615.13 KIK42762.1 - 0.66 10.3 19.7 2.8 8.2 4.8 2.7 1 1 1 2 2 2 0 Tho complex subunit 7 DUF4145 PF13643.6 KIK42762.1 - 0.8 9.9 8.8 1.1 9.4 0.0 3.9 2 1 0 2 2 1 0 Domain of unknown function (DUF4145) TPR_MLP1_2 PF07926.12 KIK42762.1 - 1.4 9.0 21.6 3.2 7.8 11.7 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Seadorna_VP6 PF07407.11 KIK42762.1 - 1.7 7.5 9.4 3.4 6.5 9.0 1.5 1 1 0 1 1 1 0 Seadornavirus VP6 protein DLP_helical PF18709.1 KIK42762.1 - 2.1 7.4 15.0 0.12 11.6 2.1 2.5 1 1 1 2 2 2 0 Dynamin-like helical domain FlaC_arch PF05377.11 KIK42762.1 - 2.3 8.7 24.1 0.62 10.5 1.0 5.2 2 2 3 5 5 5 0 Flagella accessory protein C (FlaC) KASH_CCD PF14662.6 KIK42762.1 - 2.4 7.9 24.7 0.8 9.5 12.9 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH PRKG1_interact PF15898.5 KIK42762.1 - 2.8 8.9 27.9 1.4 9.8 8.0 4.0 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain CENP-F_leu_zip PF10473.9 KIK42762.1 - 3.1 7.8 25.3 0.17 11.9 14.4 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fungal_TACC PF12709.7 KIK42762.1 - 3.2 8.3 20.4 1.9 9.0 0.3 4.3 1 1 3 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF1664 PF07889.12 KIK42762.1 - 3.9 7.5 16.1 2.4 8.2 3.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Geminin PF07412.12 KIK42762.1 - 4.3 7.0 20.3 1.8e+04 -4.8 20.3 3.1 1 1 0 1 1 0 0 Geminin MCC-bdg_PDZ PF10506.9 KIK42762.1 - 4.3 7.4 6.5 25 5.0 1.0 2.7 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF29 PF01724.16 KIK42762.1 - 6.7 6.9 10.8 13 6.0 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF29 Herpes_BTRF1 PF04682.12 KIK42764.1 - 0.032 13.6 0.0 0.033 13.5 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus BTRF1 protein conserved region DUF3040 PF11239.8 KIK42766.1 - 0.033 14.4 0.1 0.045 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF1754 PF08555.10 KIK42768.1 - 1.7 9.5 10.7 4.3 8.2 10.7 1.7 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) ATP11 PF06644.11 KIK42768.1 - 8 6.2 10.4 9.7 5.9 10.4 1.3 1 1 0 1 1 1 0 ATP11 protein DBD_Tnp_Hermes PF10683.9 KIK42769.1 - 0.04 13.6 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain DUF4413 PF14372.6 KIK42771.1 - 0.00095 19.5 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) YkyB PF14177.6 KIK42771.1 - 0.14 12.5 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 YkyB-like protein Dimer_Tnp_hAT PF05699.14 KIK42772.1 - 6.3e-13 48.3 0.1 8.4e-13 47.9 0.1 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HSP20 PF00011.21 KIK42777.1 - 0.0011 19.1 0.1 0.0012 19.0 0.1 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family TauD PF02668.16 KIK42778.1 - 2.2e-05 24.4 0.0 0.0026 17.6 0.0 2.1 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HTH_28 PF13518.6 KIK42779.1 - 0.0027 17.8 0.1 0.0034 17.5 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain PAX PF00292.18 KIK42779.1 - 0.003 17.5 0.0 0.0037 17.2 0.0 1.0 1 0 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.6 KIK42779.1 - 0.0039 17.8 0.1 0.034 14.8 0.0 2.0 1 1 1 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KIK42779.1 - 0.029 14.2 0.1 0.044 13.6 0.1 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.6 KIK42779.1 - 0.056 13.5 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn helix GYF PF02213.16 KIK42779.1 - 0.16 11.6 0.6 0.76 9.5 0.2 2.1 2 0 0 2 2 2 0 GYF domain AAA_lid_4 PF17864.1 KIK42779.1 - 0.35 10.7 1.3 14 5.5 0.0 2.1 1 1 1 2 2 2 0 RuvB AAA lid domain DDE_3 PF13358.6 KIK42780.1 - 4.4e-08 33.0 0.0 4.6e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease MEDS PF14417.6 KIK42780.1 - 0.039 13.8 0.0 0.039 13.8 0.0 1.0 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain DDE_3 PF13358.6 KIK42781.1 - 2.8e-09 36.9 0.1 3.6e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease KDZ PF18758.1 KIK42783.1 - 8.1e-66 221.8 0.1 2e-65 220.5 0.1 1.7 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK42783.1 - 3.3e-44 149.4 0.3 1.4e-43 147.4 0.0 2.3 3 0 0 3 3 3 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK42783.1 - 2e-08 34.3 0.1 7.7e-08 32.4 0.1 2.0 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIK42783.1 - 0.0032 17.3 0.0 0.0032 17.3 0.0 2.2 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 KIK42783.1 - 0.0092 16.1 10.6 0.0092 16.1 10.6 2.3 3 0 0 3 3 3 1 B-box zinc finger CEBP_ZZ PF16366.5 KIK42783.1 - 3.2 8.1 13.3 1.3 9.3 9.9 2.1 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Cauli_VI PF01693.16 KIK42784.1 - 8.1e-07 29.3 0.1 1e-06 28.9 0.1 1.1 1 0 0 1 1 1 1 Caulimovirus viroplasmin GOLD_2 PF13897.6 KIK42786.1 - 2.5 8.6 4.6 0.61 10.6 0.5 1.9 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking DUF805 PF05656.14 KIK42789.1 - 7.9 7.0 8.6 23 5.5 8.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF805) zf-C2H2_4 PF13894.6 KIK42793.1 - 0.00053 20.6 7.6 0.016 16.0 0.4 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK42793.1 - 0.0024 18.3 12.4 0.014 15.8 1.2 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KIK42793.1 - 0.0097 15.6 4.6 0.027 14.2 0.9 3.2 2 1 1 3 3 3 1 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KIK42793.1 - 0.018 15.0 2.0 0.018 15.0 2.0 3.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK42793.1 - 0.21 12.1 0.3 0.21 12.1 0.3 3.5 4 0 0 4 4 4 0 Zinc-finger double domain HSP20 PF00011.21 KIK42794.1 - 1.1e-22 80.1 0.0 2.2e-22 79.1 0.0 1.5 1 1 1 2 2 2 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIK42794.1 - 6e-10 38.5 0.0 1e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF4097 PF13349.6 KIK42794.1 - 0.018 14.4 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Putative adhesin CS PF04969.16 KIK42794.1 - 0.032 15.2 0.0 0.048 14.7 0.0 1.5 1 1 0 1 1 1 0 CS domain BON PF04972.17 KIK42794.1 - 0.11 12.8 0.0 2.3 8.6 0.0 2.1 2 0 0 2 2 2 0 BON domain LRIF1 PF15741.5 KIK42799.1 - 0.025 13.2 0.0 0.025 13.2 0.0 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 MMPL PF03176.15 KIK42806.1 - 0.088 11.7 1.5 0.18 10.7 1.5 1.5 1 0 0 1 1 1 0 MMPL family TauD PF02668.16 KIK42807.1 - 1.9e-58 198.4 0.7 2.4e-58 198.1 0.7 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cyt-b5 PF00173.28 KIK42808.1 - 8.5e-19 67.5 0.0 1.5e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IKBKB_SDD PF18397.1 KIK42810.1 - 0.084 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain PBP1_TM PF14812.6 KIK42810.1 - 0.15 12.4 1.7 0.24 11.8 1.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RVT_thumb PF06817.14 KIK42811.1 - 0.0088 15.9 0.0 0.028 14.2 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase thumb domain DUF4763 PF15960.5 KIK42813.1 - 0.19 11.0 0.1 0.32 10.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) RNA_pol_A_bac PF01000.26 KIK42816.1 - 4.8e-23 81.7 0.0 7.9e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KIK42816.1 - 9.9e-17 60.1 0.0 1.8e-16 59.3 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Dpoe2NT PF12213.8 KIK42817.1 - 0.13 12.5 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal JmjC PF02373.22 KIK42818.1 - 1.4e-15 57.7 0.0 3.5e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KIK42818.1 - 0.00094 19.0 0.1 0.035 13.8 0.1 2.6 1 1 0 1 1 1 1 Cupin-like domain C1_1 PF00130.22 KIK42818.1 - 0.0078 16.1 3.6 0.022 14.6 3.6 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 KIK42818.1 - 0.015 15.4 1.3 0.043 13.9 1.3 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger Prok-RING_2 PF14445.6 KIK42818.1 - 0.8 9.9 11.6 0.093 12.9 2.7 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 FYVE PF01363.21 KIK42818.1 - 1.2 9.3 13.0 0.063 13.4 6.8 2.2 2 0 0 2 2 2 0 FYVE zinc finger Response_reg PF00072.24 KIK42819.1 - 6.6e-23 81.0 0.1 8.3e-17 61.4 0.1 2.5 2 0 0 2 2 2 2 Response regulator receiver domain Oxidored_nitro PF00148.19 KIK42819.1 - 0.045 12.5 0.0 0.073 11.8 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase DUF3546 PF12066.8 KIK42820.1 - 1.5e-15 57.4 1.9 5.1e-15 55.6 0.0 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 KIK42820.1 - 2.3e-15 57.5 0.6 2.3e-15 57.5 0.6 3.7 2 2 2 4 4 4 1 Arsenite-resistance protein 2 RRM_1 PF00076.22 KIK42820.1 - 0.00077 19.2 0.0 1.8 8.5 0.0 3.6 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4187 PF13821.6 KIK42820.1 - 0.0014 18.4 0.8 0.0037 17.0 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-C2H2_2 PF12756.7 KIK42820.1 - 0.039 14.3 1.7 0.5 10.7 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DFF-C PF09033.10 KIK42820.1 - 2.3 8.1 8.3 0.14 12.1 2.6 1.9 2 0 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain zf-C2H2 PF00096.26 KIK42820.1 - 3.5 8.3 4.3 1.4 9.5 1.5 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type RGS12_usC PF16612.5 KIK42821.1 - 0.079 13.4 3.6 3.9 7.9 0.5 2.3 2 0 0 2 2 2 0 C-terminal unstructured region of RGS12 Ribosomal_L34e PF01199.18 KIK42822.1 - 0.017 15.4 0.4 0.019 15.3 0.4 1.2 1 1 0 1 1 1 0 Ribosomal protein L34e NCBP3 PF10309.9 KIK42823.1 - 1e-11 44.5 0.0 1.8e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 FoP_duplication PF13865.6 KIK42823.1 - 0.00085 19.8 14.1 0.015 15.8 0.3 2.9 2 1 2 4 4 4 2 C-terminal duplication domain of Friend of PRMT1 KH_8 PF17903.1 KIK42825.1 - 6.5e-33 112.7 0.2 1.6e-31 108.2 0.0 2.4 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 KIK42825.1 - 0.0012 18.7 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KIK42825.1 - 0.034 14.0 0.0 0.096 12.6 0.0 1.8 1 0 0 1 1 1 0 KH domain GTP_cyclohydroI PF01227.22 KIK42825.1 - 0.066 12.6 0.0 0.17 11.3 0.0 1.7 1 0 0 1 1 1 0 GTP cyclohydrolase I DUF3040 PF11239.8 KIK42827.1 - 0.33 11.2 8.8 9.8 6.5 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Ribosomal_S7 PF00177.21 KIK42828.1 - 4e-09 36.3 0.2 4.6e-09 36.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Nucleos_tra2_N PF01773.20 KIK42830.1 - 0.18 12.4 4.3 9.5 6.9 0.1 3.6 3 0 0 3 3 3 0 Na+ dependent nucleoside transporter N-terminus Sdh_cyt PF01127.22 KIK42830.1 - 4.1 7.4 12.3 4.4 7.4 0.2 4.1 3 1 0 4 4 4 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit IGFBP PF00219.18 KIK42831.1 - 0.0059 17.2 3.4 0.0059 17.2 3.4 1.9 2 0 0 2 2 2 1 Insulin-like growth factor binding protein WD40 PF00400.32 KIK42832.1 - 6.3e-18 64.8 12.5 8.7e-06 26.4 2.3 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42832.1 - 7.1e-08 32.6 0.1 0.058 13.7 0.0 4.4 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK42832.1 - 0.00041 20.3 0.3 0.0057 16.6 0.1 2.6 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KIK42832.1 - 0.00085 17.5 0.0 0.18 9.8 0.0 2.2 2 0 0 2 2 2 2 IKI3 family Cytochrom_D1 PF02239.16 KIK42832.1 - 0.024 13.2 0.1 0.14 10.6 0.0 2.1 1 1 0 2 2 2 0 Cytochrome D1 heme domain BBS2_N PF14781.6 KIK42832.1 - 0.046 13.6 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Tti2 PF10521.9 KIK42833.1 - 2.2e-35 122.6 0.0 2.9e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Tti2 family MitoNEET_N PF10660.9 KIK42833.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus DSPc PF00782.20 KIK42835.1 - 7.7e-28 97.0 0.0 9.2e-28 96.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIK42835.1 - 0.00094 18.8 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FGAR-AT_N PF18076.1 KIK42835.1 - 0.056 13.4 0.0 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase N-terminal PTPlike_phytase PF14566.6 KIK42835.1 - 0.13 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate TrmE_N PF10396.9 KIK42836.1 - 1e-36 125.8 0.0 1.7e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 KIK42836.1 - 1.2e-24 87.7 0.0 1.6e-24 87.3 0.0 1.1 1 0 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 KIK42836.1 - 8.8e-18 64.4 0.0 1.8e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KIK42836.1 - 5.1e-05 23.4 0.0 0.00033 20.8 0.0 2.0 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.18 KIK42836.1 - 0.0011 18.5 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 KIK42836.1 - 0.064 13.8 0.0 0.22 12.0 0.0 1.9 2 0 0 2 2 2 0 ABC transporter EF-hand_1 PF00036.32 KIK42837.1 - 1.1e-26 90.3 11.0 6.8e-06 25.3 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KIK42837.1 - 3.5e-24 85.0 5.1 4.6e-14 52.6 1.4 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KIK42837.1 - 1.4e-21 74.5 6.1 2.2e-05 24.0 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KIK42837.1 - 6.7e-18 63.3 12.8 2.6e-05 23.5 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KIK42837.1 - 9.3e-12 44.6 13.0 5.7e-05 22.9 1.1 4.4 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KIK42837.1 - 7.3e-06 26.3 0.0 0.036 14.4 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KIK42837.1 - 1e-05 25.4 6.1 0.0057 16.6 0.5 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KIK42837.1 - 0.033 14.5 0.1 4.4 7.7 0.1 2.9 2 1 1 3 3 3 0 EF-hand domain Dockerin_1 PF00404.18 KIK42837.1 - 0.1 12.8 2.6 1 9.6 1.4 2.9 2 2 2 4 4 4 0 Dockerin type I domain WD40 PF00400.32 KIK42840.1 - 9.8e-06 26.2 20.4 0.13 13.2 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat GRP PF07172.11 KIK42843.1 - 0.0039 17.8 25.1 0.027 15.2 24.0 2.2 2 0 0 2 2 2 1 Glycine rich protein family DUF2207 PF09972.9 KIK42843.1 - 0.2 10.4 0.1 0.55 8.9 0.1 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) MBOAT PF03062.19 KIK42844.1 - 1.2e-44 153.1 6.2 2.8e-44 151.9 6.2 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Ribosomal_L18 PF17135.4 KIK42845.1 - 1e-89 298.9 2.8 1.1e-89 298.8 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KIK42845.1 - 0.0043 17.7 0.0 0.0099 16.6 0.0 1.7 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RRM_1 PF00076.22 KIK42846.1 - 1.4e-16 60.1 0.0 1.9e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIK42846.1 - 6.4e-05 22.6 0.0 8.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2HC5 PF06221.13 KIK42848.1 - 0.0066 16.4 0.9 0.016 15.2 0.9 1.6 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type IBR PF01485.21 KIK42848.1 - 0.082 13.1 1.7 0.14 12.4 1.7 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2H2_4 PF13894.6 KIK42848.1 - 0.28 12.2 9.3 5.8 8.0 2.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK42848.1 - 0.28 11.7 0.1 0.28 11.7 0.1 2.6 3 0 0 3 3 3 0 Zinc-finger double domain DUF2752 PF10825.8 KIK42848.1 - 1.6 8.8 7.5 4.3 7.5 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2752) ADH_N PF08240.12 KIK42851.1 - 0.037 13.9 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain GN3L_Grn1 PF08701.11 KIK42853.1 - 6.9e-20 70.9 17.9 2.1e-19 69.4 17.9 1.9 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KIK42853.1 - 4.1e-13 49.4 0.3 1.3e-09 38.1 0.0 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK42853.1 - 3e-06 27.2 0.0 8.8e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KIK42853.1 - 3.2e-06 27.3 6.1 0.0023 18.0 0.0 4.0 2 2 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 KIK42853.1 - 0.00041 19.9 0.0 0.021 14.3 0.0 2.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KIK42853.1 - 0.00053 19.5 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KIK42853.1 - 0.00083 18.9 0.1 0.27 10.7 0.1 2.7 2 1 0 2 2 2 2 Ferrous iron transport protein B AIG1 PF04548.16 KIK42853.1 - 0.0031 16.9 2.0 0.0061 15.9 0.0 2.4 3 0 0 3 3 3 1 AIG1 family An_peroxidase PF03098.15 KIK42858.1 - 9.8e-31 106.9 0.0 1.7e-18 66.5 0.0 3.2 1 1 2 3 3 3 3 Animal haem peroxidase DUF5575 PF17738.1 KIK42858.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5575) Granulin PF00396.18 KIK42859.1 - 0.91 9.9 11.6 4.1 7.8 8.0 2.3 1 1 1 2 2 2 0 Granulin Amb_V_allergen PF03913.13 KIK42859.1 - 1.9 8.5 14.8 0.44 10.5 11.4 1.7 2 0 0 2 2 2 0 Amb V Allergen Pterin_bind PF00809.22 KIK42862.1 - 2e-61 207.8 0.0 2.6e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KIK42862.1 - 1.1e-34 119.3 0.0 1.9e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) HA2 PF04408.23 KIK42863.1 - 3.8e-23 81.8 0.0 9.2e-23 80.6 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIK42863.1 - 4.5e-22 78.2 0.0 2.2e-21 76.0 0.0 2.2 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIK42863.1 - 1.6e-10 41.3 0.0 9.5e-10 38.8 0.0 2.3 3 0 0 3 3 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK42863.1 - 1.2e-07 31.7 0.2 2.6e-07 30.6 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.22 KIK42863.1 - 1.6e-05 24.7 0.7 5.7e-05 22.8 0.1 2.2 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KIK42863.1 - 0.00044 20.5 0.1 0.0017 18.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KIK42863.1 - 0.00076 19.8 0.1 0.0017 18.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KIK42863.1 - 0.0072 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 KIK42863.1 - 0.021 14.8 0.1 0.045 13.7 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain ResIII PF04851.15 KIK42863.1 - 0.022 14.8 0.1 3.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 KIK42863.1 - 0.026 13.6 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 KIK42863.1 - 0.032 14.0 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain CCCAP PF15964.5 KIK42863.1 - 0.04 12.2 0.2 0.06 11.6 0.2 1.1 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family AAA_7 PF12775.7 KIK42863.1 - 0.042 13.4 0.1 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 KIK42863.1 - 0.068 12.6 0.0 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 KIK42863.1 - 0.11 12.5 0.0 1.4 9.0 0.0 2.4 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 KIK42863.1 - 0.13 11.1 0.1 3.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain vATP-synt_E PF01991.18 KIK42864.1 - 1.4e-53 181.3 11.0 1.6e-53 181.1 11.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit PHM7_cyt PF14703.6 KIK42864.1 - 0.24 11.6 4.1 0.37 11.0 4.1 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Paf67 PF10255.9 KIK42865.1 - 1.5e-136 455.6 0.0 2.1e-136 455.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 Glyco_hyd_65N_2 PF14498.6 KIK42866.1 - 1.6e-46 159.1 0.1 3.3e-46 158.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain PAP_assoc PF03828.19 KIK42867.1 - 0.0011 19.1 0.1 0.0063 16.7 0.1 2.3 1 1 0 1 1 1 1 Cid1 family poly A polymerase Pkinase PF00069.25 KIK42868.1 - 2.7e-71 240.0 0.0 3.5e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK42868.1 - 4.2e-34 118.0 0.0 5.8e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KIK42868.1 - 9.1e-15 55.1 3.6 2.2e-14 53.9 3.6 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KIK42868.1 - 2.1e-05 23.7 0.0 3.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KIK42868.1 - 0.0017 17.8 0.0 0.004 16.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KIK42868.1 - 0.1 12.2 0.0 2.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ras PF00071.22 KIK42870.1 - 2.2e-31 108.6 0.4 3e-29 101.7 0.4 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KIK42870.1 - 2.6e-22 79.3 0.5 7.4e-13 48.8 0.0 2.6 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KIK42870.1 - 1.8e-05 24.2 0.2 4e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KIK42870.1 - 4.4e-05 23.0 0.0 0.00041 19.9 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family TniB PF05621.11 KIK42870.1 - 0.0087 15.5 0.0 2.1 7.7 0.0 2.4 2 1 0 2 2 2 2 Bacterial TniB protein G-alpha PF00503.20 KIK42870.1 - 0.018 14.2 0.8 0.2 10.8 0.2 2.3 1 1 1 2 2 2 0 G-protein alpha subunit SNARE PF05739.19 KIK42871.1 - 4.6e-07 29.7 0.7 7.8e-07 29.0 0.2 1.6 2 0 0 2 2 2 1 SNARE domain Flp1_like PF16982.5 KIK42871.1 - 0.54 9.7 5.3 0.97 8.9 5.3 1.4 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain Mss4 PF04421.13 KIK42872.1 - 2.5e-15 56.4 0.0 3.4e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Mss4 protein GATase PF00117.28 KIK42874.1 - 2.7e-09 37.1 0.3 2.7e-08 33.8 0.3 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KIK42874.1 - 0.00062 19.6 0.0 0.00093 19.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.28 KIK42875.1 - 5.8e-10 39.2 0.1 1.8e-09 37.7 0.1 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KIK42875.1 - 6.1e-05 22.9 0.0 8.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.14 KIK42875.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain CUE PF02845.16 KIK42876.1 - 1.3e-09 37.6 0.0 2e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 CUE domain ODV-E18 PF10717.9 KIK42876.1 - 0.11 12.4 0.3 0.19 11.6 0.3 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Cue1_U7BR PF18499.1 KIK42876.1 - 0.26 11.3 0.8 0.62 10.2 0.8 1.6 1 1 0 1 1 1 0 Ubc7p-binding region of Cue1 Pkinase PF00069.25 KIK42880.1 - 1.8e-49 168.5 0.0 2.4e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK42880.1 - 9.9e-27 93.8 0.0 1.3e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK42880.1 - 0.0009 19.2 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK42880.1 - 0.0026 17.1 0.0 0.0088 15.4 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIK42880.1 - 0.023 13.5 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KIK42880.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain DUF987 PF06174.11 KIK42880.1 - 0.16 11.9 0.1 0.79 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF987) Ins_P5_2-kin PF06090.12 KIK42881.1 - 4.3e-74 249.9 0.0 5e-74 249.7 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Rib_5-P_isom_A PF06026.14 KIK42882.1 - 3.8e-60 202.4 0.0 5e-60 202.0 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 KIK42882.1 - 0.082 12.8 0.0 2.4 8.1 0.0 2.3 1 1 0 1 1 1 0 DeoR C terminal sensor domain Tfb5 PF06331.12 KIK42884.1 - 6.9e-16 58.0 0.8 7.4e-16 57.9 0.8 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 EPSP_synthase PF00275.20 KIK42886.1 - 3.4e-123 411.4 0.1 5.2e-123 410.8 0.1 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KIK42886.1 - 5.6e-99 330.6 0.0 1e-98 329.7 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KIK42886.1 - 1.9e-52 178.8 0.0 5.1e-52 177.4 0.0 1.8 2 0 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.22 KIK42886.1 - 2e-34 119.0 0.0 1.5e-33 116.1 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KIK42886.1 - 2.3e-25 88.6 0.0 7e-25 87.1 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KIK42886.1 - 1.8e-07 30.8 0.1 5.8e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 KIK42886.1 - 6.1e-07 29.4 0.1 1.9e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 KIK42886.1 - 1.1e-06 28.7 0.0 2.6e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_16 PF13191.6 KIK42886.1 - 0.036 14.5 0.0 0.15 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KIK42886.1 - 0.055 13.6 0.0 0.76 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sacchrp_dh_NADP PF03435.18 KIK42886.1 - 0.057 13.7 0.0 2.4 8.4 0.0 2.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DIM PF08194.12 KIK42887.1 - 0.056 13.7 1.2 0.087 13.0 1.2 1.3 1 0 0 1 1 1 0 DIM protein DUF3328 PF11807.8 KIK42889.1 - 3e-63 213.5 2.5 3.6e-63 213.3 2.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KIK42890.1 - 8.3e-50 169.6 0.3 1.1e-49 169.2 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) NopRA1 PF16201.5 KIK42890.1 - 0.092 12.3 0.1 0.65 9.6 0.2 1.9 1 1 1 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 DUF4383 PF14325.6 KIK42891.1 - 0.021 15.1 1.9 0.021 15.1 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) UcrQ PF02939.16 KIK42891.1 - 0.097 12.6 0.1 0.25 11.3 0.1 1.7 1 0 0 1 1 1 0 UcrQ family RNase_H_2 PF13482.6 KIK42891.1 - 0.14 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 RNase_H superfamily DUF3290 PF11694.8 KIK42891.1 - 2 8.4 5.5 1.5 8.8 3.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3290) MIG-14_Wnt-bd PF06664.12 KIK42891.1 - 2 7.6 15.9 0.078 12.2 8.4 2.0 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion DUF3328 PF11807.8 KIK42893.1 - 9.9e-13 48.4 0.0 9.9e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) QRPTase_C PF01729.19 KIK42896.1 - 0.058 13.2 0.4 0.09 12.5 0.4 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Med8 PF10232.9 KIK42896.1 - 1.2 8.7 6.9 0.06 12.9 0.8 1.9 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 HMG_box PF00505.19 KIK42897.1 - 1.3e-22 80.0 6.8 4.8e-13 49.3 0.3 3.1 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK42897.1 - 1.7e-13 50.9 3.4 8e-08 32.8 0.2 3.1 1 1 2 3 3 3 2 HMG-box domain MlaC PF05494.12 KIK42897.1 - 0.084 12.6 0.8 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 MlaC protein DUF3328 PF11807.8 KIK42898.1 - 6.3e-58 196.1 0.4 7.9e-58 195.8 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) NDUF_B8 PF05821.11 KIK42898.1 - 0.091 12.6 0.9 0.16 11.8 0.9 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Amidase PF01425.21 KIK42900.1 - 2.2e-107 359.9 0.0 5.3e-107 358.6 0.0 1.6 1 1 0 1 1 1 1 Amidase MMR_HSR1 PF01926.23 KIK42901.1 - 5.2e-12 45.9 0.0 6.8e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK42901.1 - 2.7e-07 30.1 0.0 3e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 KIK42901.1 - 2.8e-06 27.5 0.0 7.9e-06 26.1 0.0 1.9 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KIK42901.1 - 7.2e-06 26.0 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KIK42901.1 - 0.00053 20.4 0.0 0.00073 20.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Ras PF00071.22 KIK42901.1 - 0.0013 18.4 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Ras family ABC_tran PF00005.27 KIK42901.1 - 0.0016 18.9 0.0 0.0027 18.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 KIK42901.1 - 0.0044 17.1 0.0 0.011 15.8 0.0 1.5 1 1 1 2 2 2 1 Dynamin family DUF815 PF05673.13 KIK42901.1 - 0.018 14.2 0.1 0.053 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KIK42901.1 - 0.028 14.8 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KIK42901.1 - 0.032 14.0 0.1 0.038 13.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK42901.1 - 0.055 13.7 0.0 0.091 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 KIK42901.1 - 0.059 12.4 0.1 0.078 12.0 0.1 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Gtr1_RagA PF04670.12 KIK42901.1 - 0.069 12.5 0.0 0.084 12.2 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region NACHT PF05729.12 KIK42901.1 - 0.12 12.3 0.0 0.55 10.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 KIK42901.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.14 KIK42901.1 - 0.16 11.2 0.0 0.16 11.2 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain MMR_HSR1 PF01926.23 KIK42902.1 - 4.4e-11 42.9 0.0 8.8e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK42902.1 - 1.7e-05 24.3 0.0 2.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIK42902.1 - 2.9e-05 24.2 0.0 5.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 KIK42902.1 - 5e-05 23.3 0.0 0.00012 22.0 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KIK42902.1 - 0.0015 19.0 0.0 0.0029 18.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KIK42902.1 - 0.012 15.9 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Cas_NE0113 PF09623.10 KIK42902.1 - 0.013 15.2 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) Roc PF08477.13 KIK42902.1 - 0.025 14.8 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 KIK42902.1 - 0.049 13.7 0.1 0.087 12.9 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain IIGP PF05049.13 KIK42902.1 - 0.073 12.1 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 KIK42902.1 - 0.089 13.2 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 KIK42902.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 KIK42902.1 - 0.16 12.4 0.0 0.73 10.3 0.0 2.1 3 0 0 3 3 3 0 RNA helicase NAD_kinase PF01513.21 KIK42905.1 - 1.3e-73 247.8 0.0 2.4e-73 246.9 0.0 1.5 1 1 0 1 1 1 1 ATP-NAD kinase ANAPC15 PF15243.6 KIK42905.1 - 0.72 10.3 8.6 0.44 11.0 5.8 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 NOA36 PF06524.12 KIK42905.1 - 3.2 7.0 6.3 5.9 6.1 6.3 1.3 1 0 0 1 1 1 0 NOA36 protein Q_salvage PF10343.9 KIK42906.1 - 3.8e-10 39.8 0.0 1.1e-06 28.5 0.0 2.3 2 1 0 2 2 2 2 Potential Queuosine, Q, salvage protein family YqeY PF09424.10 KIK42907.1 - 3.5e-27 95.2 0.3 4e-27 95.1 0.3 1.0 1 0 0 1 1 1 1 Yqey-like protein YtzH PF14165.6 KIK42907.1 - 0.004 17.5 0.1 1.4 9.4 0.1 2.3 2 0 0 2 2 2 2 YtzH-like protein FixH PF05751.11 KIK42907.1 - 0.06 13.4 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 FixH zf-rbx1 PF12678.7 KIK42908.1 - 2.4e-12 46.9 2.1 5.2e-12 45.9 2.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KIK42908.1 - 2e-09 37.6 6.2 2e-09 37.6 2.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KIK42908.1 - 5.2e-07 29.4 2.6 1.4e-06 28.0 2.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK42908.1 - 9.2e-07 28.6 3.4 9.2e-07 28.6 3.4 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK42908.1 - 3.7e-06 26.9 2.2 1e-05 25.5 2.2 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIK42908.1 - 6.5e-05 22.7 4.4 0.00052 19.8 1.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KIK42908.1 - 0.00041 19.9 0.6 0.0011 18.6 0.6 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KIK42908.1 - 0.0019 18.1 4.1 0.0091 15.9 4.4 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 KIK42908.1 - 0.0029 17.3 0.3 0.0029 17.3 0.3 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KIK42908.1 - 0.0035 17.4 3.8 0.0099 15.9 3.8 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KIK42908.1 - 0.0035 17.2 4.8 0.01 15.7 4.9 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KIK42908.1 - 0.0076 16.4 1.6 0.017 15.3 1.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KIK42908.1 - 0.055 13.6 0.5 0.12 12.5 0.5 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KIK42908.1 - 0.31 11.4 2.5 0.66 10.3 2.5 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KIK42908.1 - 0.78 9.6 3.8 0.45 10.3 1.0 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain CYYR1 PF10873.8 KIK42908.1 - 3.2 8.2 9.6 1.1 9.7 0.0 2.8 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Amidohydro_3 PF07969.11 KIK42909.1 - 3.9e-82 277.2 0.0 4.9e-82 276.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KIK42909.1 - 5.9e-11 42.3 0.0 2.2e-09 37.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family SNF2_N PF00176.23 KIK42910.1 - 9.2e-55 185.8 0.0 1.5e-54 185.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK42910.1 - 7.6e-15 55.2 0.0 1.4e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK42910.1 - 8.9e-10 38.8 0.0 1.9e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KIK42910.1 - 7.8e-06 25.3 0.0 1.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF2439 PF10382.9 KIK42910.1 - 0.026 14.8 0.7 7.6 6.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2439) Rad54_N PF08658.10 KIK42910.1 - 0.2 11.8 0.4 1.2 9.3 0.0 2.3 3 0 0 3 3 3 0 Rad54 N terminal GEN1_C PF18380.1 KIK42911.1 - 3.9e-27 95.2 0.3 1.2e-26 93.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 KIK42911.1 - 8e-18 64.6 0.0 1.4e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KIK42911.1 - 2.1e-05 24.9 0.0 5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KIK42911.1 - 0.0029 17.1 0.0 0.0049 16.4 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing MMR_HSR1 PF01926.23 KIK42912.1 - 7.1e-12 45.4 0.0 1.3e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK42912.1 - 9.1e-08 31.7 0.0 1.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KIK42912.1 - 9.1e-06 25.7 0.0 2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 KIK42912.1 - 0.0001 22.9 0.0 0.00016 22.2 0.0 1.5 1 1 0 1 1 1 1 ABC transporter Roc PF08477.13 KIK42912.1 - 0.00018 21.7 0.1 0.0018 18.5 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 KIK42912.1 - 0.00028 20.2 0.0 0.00059 19.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 KIK42912.1 - 0.00029 21.1 0.1 0.0024 18.1 0.1 2.5 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KIK42912.1 - 0.00037 20.6 0.0 0.00066 19.8 0.0 1.8 1 1 0 1 1 1 1 Dynamin family DUF4376 PF14301.6 KIK42912.1 - 0.0041 17.4 0.0 0.0077 16.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4376) AAA_16 PF13191.6 KIK42912.1 - 0.0046 17.4 0.0 0.006 17.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Ras PF00071.22 KIK42912.1 - 0.011 15.3 0.0 0.036 13.7 0.0 1.7 2 0 0 2 2 2 0 Ras family AAA_23 PF13476.6 KIK42912.1 - 0.016 15.8 0.1 0.042 14.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KIK42912.1 - 0.023 14.4 0.0 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF2126 PF09899.9 KIK42912.1 - 0.031 12.4 0.0 0.043 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) KAP_NTPase PF07693.14 KIK42912.1 - 0.039 13.2 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.6 KIK42912.1 - 0.049 13.3 0.4 0.25 11.0 0.4 2.1 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.6 KIK42912.1 - 0.059 12.0 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIK42912.1 - 0.079 13.2 0.2 0.51 10.6 0.2 2.2 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK42912.1 - 0.13 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.13 KIK42912.1 - 0.13 11.4 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SRPRB PF09439.10 KIK42912.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit IIGP PF05049.13 KIK42912.1 - 0.15 11.0 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KIK42913.1 - 3.2e-11 43.3 0.0 5e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK42913.1 - 1.2e-07 31.2 0.0 2.5e-07 30.3 0.0 1.5 1 1 1 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 KIK42913.1 - 1e-06 28.8 0.1 2.1e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase IIGP PF05049.13 KIK42913.1 - 8.7e-05 21.7 0.0 0.00014 21.1 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 KIK42913.1 - 0.00042 20.4 0.3 0.082 13.0 0.2 2.3 1 1 1 2 2 2 1 Dynamin family Roc PF08477.13 KIK42913.1 - 0.001 19.3 0.1 0.0027 17.9 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 KIK42913.1 - 0.0016 17.6 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 KIK42913.1 - 0.0016 18.8 0.1 0.0039 17.6 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KIK42913.1 - 0.0023 17.5 0.2 0.0037 16.8 0.2 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Ras PF00071.22 KIK42913.1 - 0.0024 17.5 0.1 0.0063 16.1 0.1 1.8 1 1 0 1 1 1 1 Ras family AAA_22 PF13401.6 KIK42913.1 - 0.0024 18.1 0.2 0.0097 16.2 0.1 2.1 2 1 0 2 2 2 1 AAA domain Septin PF00735.18 KIK42913.1 - 0.0031 16.9 0.2 0.0052 16.1 0.2 1.4 1 0 0 1 1 1 1 Septin Gtr1_RagA PF04670.12 KIK42913.1 - 0.0039 16.6 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KIK42913.1 - 0.0045 16.5 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 KIK42913.1 - 0.0095 16.5 0.0 0.015 15.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Sigma54_activat PF00158.26 KIK42913.1 - 0.011 15.4 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain MCM PF00493.23 KIK42913.1 - 0.013 14.6 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain SRPRB PF09439.10 KIK42913.1 - 0.037 13.5 0.1 0.057 12.9 0.1 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 KIK42913.1 - 0.046 14.3 0.1 0.081 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK42913.1 - 0.049 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Lon_2 PF13337.6 KIK42913.1 - 0.05 12.1 0.0 0.07 11.7 0.0 1.1 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease RNA_helicase PF00910.22 KIK42913.1 - 0.051 14.0 0.1 0.3 11.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 KIK42913.1 - 0.056 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KIK42913.1 - 0.16 12.4 0.3 0.32 11.4 0.2 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KIK42914.1 - 1.3e-11 44.6 0.0 2.2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK42914.1 - 6.5e-08 32.1 0.0 7.9e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 KIK42914.1 - 8.7e-06 26.0 0.3 0.0027 17.9 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KIK42914.1 - 1.2e-05 25.3 0.0 3.6e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase Arf PF00025.21 KIK42914.1 - 0.00054 19.5 0.0 0.0013 18.2 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family ABC_tran PF00005.27 KIK42914.1 - 0.00091 19.8 0.1 0.0017 18.9 0.1 1.8 1 1 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 KIK42914.1 - 0.001 19.2 0.1 0.0034 17.5 0.0 1.8 2 1 1 3 3 3 1 Dynamin family Zeta_toxin PF06414.12 KIK42914.1 - 0.0011 18.3 0.0 0.0024 17.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 KIK42914.1 - 0.0051 17.1 0.0 0.019 15.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain Ras PF00071.22 KIK42914.1 - 0.0056 16.3 0.1 0.029 14.0 0.0 1.9 2 0 0 2 2 2 1 Ras family AAA_28 PF13521.6 KIK42914.1 - 0.012 15.8 0.1 0.054 13.7 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_13 PF13166.6 KIK42914.1 - 0.016 13.9 0.0 0.033 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIK42914.1 - 0.018 15.5 0.0 0.027 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KIK42914.1 - 0.04 14.5 0.2 0.13 12.8 0.1 1.9 1 1 1 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KIK42914.1 - 0.055 12.7 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain SRPRB PF09439.10 KIK42914.1 - 0.067 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF815 PF05673.13 KIK42914.1 - 0.076 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 KIK42914.1 - 0.11 12.2 0.0 0.6 9.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KIK42915.1 - 3.7e-14 52.8 0.1 4.6e-14 52.5 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KIK42915.1 - 9.3e-10 38.8 0.6 5.3e-07 29.9 0.2 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KIK42915.1 - 3.9e-09 36.3 1.8 6.4e-08 32.4 1.8 2.0 1 1 0 1 1 1 1 Ras family AIG1 PF04548.16 KIK42915.1 - 7.5e-08 32.0 0.1 8.5e-08 31.8 0.1 1.1 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIK42915.1 - 1.5e-05 25.1 1.8 0.0016 18.5 0.5 2.2 1 1 1 2 2 2 1 Dynamin family ABC_tran PF00005.27 KIK42915.1 - 1.8e-05 25.3 0.4 2.8e-05 24.7 0.4 1.4 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KIK42915.1 - 0.0002 21.3 2.6 0.00022 21.2 0.5 1.9 2 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KIK42915.1 - 0.0019 18.5 0.5 0.0042 17.3 0.5 1.7 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KIK42915.1 - 0.0085 16.6 2.7 0.021 15.4 2.7 1.8 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 KIK42915.1 - 0.0098 15.3 0.1 0.012 15.0 0.1 1.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Septin PF00735.18 KIK42915.1 - 0.016 14.5 0.7 0.035 13.4 0.5 1.6 1 1 1 2 2 2 0 Septin IIGP PF05049.13 KIK42915.1 - 0.027 13.5 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.18 KIK42915.1 - 0.036 13.6 0.6 0.052 13.1 0.6 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF87 PF01935.17 KIK42915.1 - 0.039 14.1 1.9 0.054 13.6 0.3 1.9 2 1 0 2 2 2 0 Helicase HerA, central domain ImcF-related_N PF14331.6 KIK42915.1 - 0.044 13.1 0.1 0.47 9.8 0.0 2.0 1 1 1 2 2 2 0 ImcF-related N-terminal domain AAA_16 PF13191.6 KIK42915.1 - 0.051 14.0 0.2 0.077 13.4 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.13 KIK42915.1 - 0.092 11.9 0.1 0.38 9.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_13 PF13166.6 KIK42915.1 - 0.093 11.4 0.4 0.27 9.8 0.1 1.8 1 1 0 2 2 2 0 AAA domain PEPCK_ATP PF01293.20 KIK42916.1 - 2.2e-217 722.3 0.0 2.5e-217 722.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 KIK42916.1 - 0.081 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK42916.1 - 0.11 12.3 0.1 0.31 10.8 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KIK42916.1 - 0.12 12.8 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Lentiviral_Tat PF02998.14 KIK42917.1 - 0.19 11.8 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Lentiviral Tat protein MMR_HSR1 PF01926.23 KIK42918.1 - 1.4e-23 83.1 0.0 4.3e-11 42.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AIG1 PF04548.16 KIK42918.1 - 3.2e-15 56.1 0.0 5.8e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 KIK42918.1 - 3.9e-12 46.4 0.0 1.4e-05 25.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Roc PF08477.13 KIK42918.1 - 1.3e-11 44.7 0.0 1e-05 25.7 0.0 2.9 4 0 0 4 4 2 2 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KIK42918.1 - 1.8e-10 41.1 0.2 0.00016 21.8 0.0 2.7 2 0 0 2 2 2 2 Dynamin family ABC_tran PF00005.27 KIK42918.1 - 2.3e-08 34.7 0.0 0.0061 17.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter Ras PF00071.22 KIK42918.1 - 3.4e-08 33.3 0.0 0.00047 19.8 0.0 3.1 2 1 0 2 2 2 2 Ras family AAA_16 PF13191.6 KIK42918.1 - 3.1e-07 30.9 0.1 0.003 18.0 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KIK42918.1 - 7.6e-07 29.5 0.0 0.053 13.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KIK42918.1 - 0.00021 21.0 0.2 0.24 11.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 KIK42918.1 - 0.00032 21.1 0.0 0.61 10.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase DUF815 PF05673.13 KIK42918.1 - 0.00032 20.0 0.2 0.16 11.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_24 PF13479.6 KIK42918.1 - 0.00037 20.3 0.0 0.23 11.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain Septin PF00735.18 KIK42918.1 - 0.00053 19.3 0.1 0.39 10.0 0.0 2.6 3 0 0 3 3 3 2 Septin IIGP PF05049.13 KIK42918.1 - 0.0006 19.0 0.3 0.66 9.0 0.0 2.2 2 0 0 2 2 2 2 Interferon-inducible GTPase (IIGP) Zeta_toxin PF06414.12 KIK42918.1 - 0.0015 17.9 0.0 0.6 9.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin FeoB_N PF02421.18 KIK42918.1 - 0.0019 17.7 0.0 0.66 9.5 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_18 PF13238.6 KIK42918.1 - 0.0041 17.6 0.1 1.8 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KIK42918.1 - 0.0048 17.4 1.0 2.4 8.6 0.2 2.3 2 0 0 2 2 2 1 AAA domain Arf PF00025.21 KIK42918.1 - 0.0083 15.6 0.0 0.79 9.1 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_28 PF13521.6 KIK42918.1 - 0.013 15.8 0.1 0.63 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KIK42918.1 - 0.013 15.2 0.1 1 9.0 0.0 2.6 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 KIK42918.1 - 0.014 15.0 0.0 0.94 9.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Gtr1_RagA PF04670.12 KIK42918.1 - 0.023 14.1 0.0 0.19 11.1 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_13 PF13166.6 KIK42918.1 - 0.03 13.0 0.0 0.12 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KIK42918.1 - 0.037 13.8 0.2 17 5.2 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.18 KIK42918.1 - 0.037 13.4 0.1 3 7.1 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.29 KIK42918.1 - 0.043 14.2 0.0 6 7.3 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KIK42918.1 - 0.044 13.5 0.0 3.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain TniB PF05621.11 KIK42918.1 - 0.053 12.9 0.0 3.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein TsaE PF02367.17 KIK42918.1 - 0.057 13.4 0.0 16 5.5 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE KAP_NTPase PF07693.14 KIK42918.1 - 0.089 12.0 0.0 4.2 6.5 0.0 2.4 3 0 0 3 3 2 0 KAP family P-loop domain dNK PF01712.19 KIK42918.1 - 0.15 11.9 0.1 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase Dynamin_N PF00350.23 KIK42919.1 - 3.8e-27 95.4 0.1 1.1e-26 93.8 0.1 1.8 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KIK42919.1 - 9.4e-27 93.9 0.0 2.1e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region GED PF02212.18 KIK42919.1 - 4.8e-10 39.5 0.3 4.8e-10 39.5 0.3 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIK42919.1 - 0.00018 21.6 0.8 0.0055 16.8 0.8 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KIK42919.1 - 0.0025 18.2 0.1 0.16 12.4 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_28 PF13521.6 KIK42919.1 - 0.067 13.4 0.1 0.17 12.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain GMC_oxred_C PF05199.13 KIK42922.1 - 0.0099 16.4 0.0 0.019 15.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KIK42922.1 - 0.17 11.2 0.0 12 5.2 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase MMR_HSR1 PF01926.23 KIK42923.1 - 1.2e-11 44.7 0.0 2.5e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK42923.1 - 5.6e-06 25.8 0.0 9.9e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KIK42923.1 - 4.5e-05 23.4 0.0 8.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 KIK42923.1 - 0.00012 22.2 0.0 0.00039 20.5 0.0 1.9 2 0 0 2 2 2 1 Dynamin family ABC_tran PF00005.27 KIK42923.1 - 0.00076 20.0 0.8 0.0019 18.7 0.0 2.0 3 0 0 3 3 3 1 ABC transporter Roc PF08477.13 KIK42923.1 - 0.0076 16.5 0.0 0.039 14.2 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KIK42923.1 - 0.023 15.0 0.0 0.074 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIK42923.1 - 0.028 14.8 0.3 0.4 11.0 0.3 2.6 1 1 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 KIK42923.1 - 0.062 13.4 0.1 0.16 12.0 0.1 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_23 PF13476.6 KIK42923.1 - 0.091 13.3 0.2 0.23 11.9 0.2 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KIK42925.1 - 4.4e-11 42.9 0.1 8.6e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK42925.1 - 2e-05 24.0 0.1 3.2e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIK42925.1 - 3.6e-05 23.9 0.5 0.012 15.6 0.3 2.5 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KIK42925.1 - 0.00025 21.0 0.3 0.00052 20.0 0.3 1.5 1 0 0 1 1 1 1 RsgA GTPase Ras PF00071.22 KIK42925.1 - 0.00025 20.7 1.5 0.004 16.8 1.5 2.2 1 1 0 1 1 1 1 Ras family ABC_tran PF00005.27 KIK42925.1 - 0.0005 20.6 0.3 0.0011 19.5 0.3 1.7 1 1 0 1 1 1 1 ABC transporter IIGP PF05049.13 KIK42925.1 - 0.0045 16.1 0.1 0.0084 15.2 0.1 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Roc PF08477.13 KIK42925.1 - 0.0077 16.4 0.4 0.034 14.4 0.1 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KIK42925.1 - 0.011 16.1 0.2 0.017 15.5 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KIK42925.1 - 0.018 15.3 0.2 0.052 13.8 0.2 1.8 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KIK42925.1 - 0.022 14.0 0.7 0.064 12.5 0.7 1.7 1 1 1 2 2 2 0 Septin AAA_23 PF13476.6 KIK42925.1 - 0.023 15.2 0.9 0.043 14.3 0.6 1.5 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 KIK42925.1 - 0.025 13.8 0.1 0.041 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KIK42925.1 - 0.036 13.6 0.1 0.41 10.1 0.2 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 KIK42925.1 - 0.037 13.8 0.1 0.067 12.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PPK2 PF03976.14 KIK42925.1 - 0.081 12.4 0.1 2.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) FeoB_N PF02421.18 KIK42925.1 - 0.095 12.2 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Sigma54_activat PF00158.26 KIK42925.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 KIK42925.1 - 0.11 12.2 0.1 0.54 9.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KIK42926.1 - 5.6e-12 45.8 0.0 1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK42926.1 - 4.4e-07 29.4 0.0 5.7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIK42926.1 - 4.6e-05 23.5 0.1 0.00015 21.9 0.1 1.8 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KIK42926.1 - 0.00035 20.5 0.0 0.00065 19.6 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 KIK42926.1 - 0.00035 21.1 0.0 0.00063 20.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Roc PF08477.13 KIK42926.1 - 0.0012 19.0 0.0 0.0045 17.2 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KIK42926.1 - 0.0022 18.2 0.1 0.011 16.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain Ras PF00071.22 KIK42926.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Ras family AAA_16 PF13191.6 KIK42926.1 - 0.017 15.5 0.0 0.019 15.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KIK42926.1 - 0.018 15.5 0.0 0.033 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK42926.1 - 0.02 14.6 0.0 0.058 13.1 0.1 1.7 2 0 0 2 2 1 0 P-loop containing region of AAA domain Arf PF00025.21 KIK42926.1 - 0.071 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family IIGP PF05049.13 KIK42926.1 - 0.08 12.0 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF815 PF05673.13 KIK42926.1 - 0.11 11.7 0.0 0.44 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_21 PF13304.6 KIK42926.1 - 0.11 12.3 0.7 1.5 8.5 0.5 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KIK42926.1 - 0.12 12.9 0.0 0.24 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KIK42926.1 - 0.14 11.8 0.0 0.63 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 KIK42926.1 - 0.16 10.8 0.0 0.27 10.0 0.0 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) FeoB_N PF02421.18 KIK42926.1 - 0.17 11.4 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B PDGF PF00341.17 KIK42927.1 - 0.0091 16.3 0.1 0.014 15.7 0.1 1.3 1 0 0 1 1 1 1 PDGF/VEGF domain DUF3712 PF12505.8 KIK42928.1 - 4.2e-98 324.3 62.4 4.3e-26 91.6 0.3 10.8 11 1 1 12 12 12 6 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KIK42928.1 - 6.8e-05 23.3 26.3 0.025 15.1 0.1 8.8 10 0 0 10 10 10 4 Late embryogenesis abundant protein WD40 PF00400.32 KIK42931.1 - 4.8e-36 122.1 13.4 8.8e-08 32.7 0.0 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42931.1 - 9.4e-12 45.1 0.2 0.017 15.4 0.0 4.1 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK42931.1 - 0.00031 20.7 0.0 0.092 12.6 0.0 2.5 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK42931.1 - 0.0012 17.6 0.2 0.024 13.3 0.2 2.5 1 1 1 3 3 3 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KIK42931.1 - 0.005 15.4 0.1 0.032 12.8 0.1 1.9 2 0 0 2 2 2 1 Cytochrome D1 heme domain WD40 PF00400.32 KIK42932.1 - 1.3e-38 130.3 20.8 2e-07 31.6 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42932.1 - 2.1e-09 37.6 0.2 0.57 10.5 0.0 4.9 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WW PF00397.26 KIK42932.1 - 8.2e-06 25.8 0.6 8.2e-06 25.8 0.6 2.9 3 0 0 3 3 3 1 WW domain PQQ_3 PF13570.6 KIK42932.1 - 0.018 15.5 3.7 22 5.7 0.0 5.0 5 0 0 5 5 5 0 PQQ-like domain Nup160 PF11715.8 KIK42932.1 - 0.02 13.6 0.2 0.5 8.9 0.1 2.9 2 2 1 3 3 3 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK42932.1 - 0.023 14.0 0.0 2.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal WD40 PF00400.32 KIK42934.1 - 2.2e-40 135.9 20.9 1.3e-07 32.2 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42934.1 - 3.5e-16 59.3 0.1 0.0091 16.3 0.0 5.2 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK42934.1 - 0.00016 20.5 0.0 2.3 6.7 0.0 3.9 1 1 3 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK42934.1 - 0.00065 19.6 0.0 0.41 10.5 0.0 2.7 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KIK42934.1 - 0.0038 16.6 0.0 2.4 7.4 0.0 2.5 2 1 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK42934.1 - 0.042 13.2 0.0 0.87 8.9 0.0 2.3 2 1 0 2 2 2 0 WD40-like domain Ge1_WD40 PF16529.5 KIK42934.1 - 0.11 11.5 0.0 37 3.1 0.0 3.6 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KIK42937.1 - 8.3e-41 137.2 27.9 7.4e-09 36.1 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK42937.1 - 3.4e-12 46.5 2.8 0.00016 21.9 0.1 4.8 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK42937.1 - 3.7e-06 25.9 0.1 0.054 12.1 0.0 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 WW PF00397.26 KIK42937.1 - 1.1e-05 25.4 1.0 1.1e-05 25.4 1.0 3.8 4 0 0 4 4 4 1 WW domain Ge1_WD40 PF16529.5 KIK42937.1 - 0.0088 15.0 0.1 2.3 7.1 0.0 3.9 2 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Peroxin-13_N PF04088.13 KIK42939.1 - 7.4e-44 149.5 0.4 1.1e-43 149.0 0.4 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 KIK42939.1 - 3.2e-11 42.7 0.8 0.00013 21.4 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KIK42939.1 - 1e-09 37.9 0.0 1.7e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KIK42939.1 - 9.6e-08 31.8 0.4 1.8e-07 30.9 0.4 1.5 1 1 0 1 1 1 1 Variant SH3 domain DUF4142 PF13628.6 KIK42941.1 - 0.047 13.9 2.4 4.9 7.4 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4142) Acetyltransf_2 PF00797.17 KIK42941.1 - 0.065 13.0 0.2 0.084 12.7 0.2 1.1 1 0 0 1 1 1 0 N-acetyltransferase O-FucT PF10250.9 KIK42949.1 - 9.4e-10 38.7 0.0 2.5e-09 37.3 0.0 1.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Snurportin1 PF11538.8 KIK42950.1 - 0.00086 19.4 5.0 0.0018 18.4 5.0 1.5 1 0 0 1 1 1 1 Snurportin1 MatE PF01554.18 KIK42951.1 - 1.2e-40 138.8 14.4 1.3e-26 93.2 8.6 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KIK42951.1 - 1.8e-07 31.3 4.6 1.8e-07 31.3 4.6 3.1 1 1 2 3 3 3 1 Polysaccharide biosynthesis C-terminal domain MurJ PF03023.14 KIK42951.1 - 9.7e-06 24.4 9.8 7.9e-05 21.4 2.8 2.7 2 1 0 2 2 2 2 Lipid II flippase MurJ Bac_surface_Ag PF01103.23 KIK42951.1 - 0.058 12.9 0.4 0.089 12.3 0.4 1.2 1 0 0 1 1 1 0 Surface antigen MatE PF01554.18 KIK42952.1 - 2.4e-07 30.5 2.6 3.1e-07 30.2 2.6 1.1 1 0 0 1 1 1 1 MatE Bac_surface_Ag PF01103.23 KIK42953.1 - 8.9e-39 133.9 0.0 1.3e-38 133.4 0.0 1.2 1 0 0 1 1 1 1 Surface antigen Ribosomal_S8 PF00410.19 KIK42954.1 - 6.1e-12 45.6 0.0 3.1e-11 43.3 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein S8 Amj PF10997.8 KIK42955.1 - 0.18 11.1 0.0 0.18 11.1 0.0 1.0 1 0 0 1 1 1 0 Alternate to MurJ Hydrophobin PF01185.18 KIK42956.1 - 1.7e-14 54.2 9.2 2e-14 54.0 9.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KIK42957.1 - 3.8e-05 24.2 8.3 0.0001 22.9 8.3 1.7 1 1 0 1 1 1 1 Fungal hydrophobin CRIM PF16978.5 KIK42958.1 - 5.4e-42 143.3 1.6 4.5e-41 140.3 0.0 2.8 3 0 0 3 3 3 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KIK42958.1 - 2.8e-32 111.2 0.5 4.6e-32 110.6 0.5 1.3 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 KIK42958.1 - 5.5e-05 23.3 0.0 0.00014 22.0 0.0 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain RA PF00788.23 KIK42958.1 - 0.00034 21.2 0.0 0.2 12.3 0.0 2.6 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain RBD PF02196.15 KIK42958.1 - 0.0032 17.5 0.0 0.24 11.5 0.0 2.6 2 0 0 2 2 2 1 Raf-like Ras-binding domain Hydrophobin PF01185.18 KIK42959.1 - 3.8e-20 72.3 8.8 4.6e-20 72.0 8.8 1.1 1 0 0 1 1 1 1 Fungal hydrophobin BIR PF00653.21 KIK42960.1 - 3.6e-36 123.7 5.8 3.7e-19 69.1 0.1 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 KIK42960.1 - 3.8e-05 23.7 0.6 0.19 11.8 0.0 3.0 3 1 0 3 3 3 2 C3HC zinc finger-like WAPL PF07814.13 KIK42961.1 - 5.7e-10 38.5 0.0 7.3e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Ldh_1_C PF02866.18 KIK42964.1 - 1.6e-48 164.8 0.0 3.6e-48 163.7 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KIK42964.1 - 1.1e-43 148.7 0.1 1.6e-43 148.2 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KIK42964.1 - 0.0011 18.1 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KIK42964.1 - 0.022 15.2 0.1 0.07 13.6 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Proteasome PF00227.26 KIK42971.1 - 2e-54 184.0 0.0 2.4e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIK42971.1 - 6.9e-13 48.0 1.7 1.1e-12 47.3 0.1 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Ribosomal_60s PF00428.19 KIK42971.1 - 0.016 15.8 0.7 0.081 13.5 0.7 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein COX15-CtaA PF02628.15 KIK42972.1 - 7.7e-109 363.7 5.6 9.3e-109 363.4 5.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein CdiI_N PF18228.1 KIK42972.1 - 0.13 12.1 0.0 1.5 8.7 0.0 2.6 3 0 0 3 3 3 0 CdiI N-terminal domain BolA PF01722.18 KIK42973.1 - 1.9e-12 47.3 0.0 6.6e-12 45.5 0.0 1.8 1 1 0 1 1 1 1 BolA-like protein Methyltransf_16 PF10294.9 KIK42974.1 - 4.9e-43 146.9 0.0 6.2e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PI3K_1B_p101 PF10486.9 KIK42975.1 - 0.13 10.1 5.2 0.16 9.7 5.2 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SR-25 PF10500.9 KIK42975.1 - 0.43 10.2 12.7 0.58 9.7 12.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CarboxypepD_reg PF13620.6 KIK42979.1 - 0.17 12.2 0.0 5.9 7.2 0.1 2.1 1 1 1 2 2 2 0 Carboxypeptidase regulatory-like domain Con-6 PF10346.9 KIK42980.1 - 3.3e-16 59.0 0.4 4.9e-16 58.5 0.4 1.3 1 0 0 1 1 1 1 Conidiation protein 6 A_deamin PF02137.18 KIK42981.1 - 5.2e-67 226.6 0.0 6.9e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF2838 PF10998.8 KIK42982.1 - 4.6e-42 142.7 11.2 9.9e-42 141.7 11.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2838) Mt_ATP-synt_D PF05873.12 KIK42983.1 - 5.6e-17 62.0 0.8 6.6e-17 61.8 0.8 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF1638 PF07796.11 KIK42983.1 - 0.029 14.5 0.2 0.04 14.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1638) DUF3445 PF11927.8 KIK42984.1 - 2.7e-68 230.0 0.0 3.5e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Aft1_HRA PF11786.8 KIK42985.1 - 4.7e-25 87.7 10.9 4.7e-25 87.7 10.9 2.3 2 0 0 2 2 2 1 Aft1 HRA domain bZIP_1 PF00170.21 KIK42985.1 - 6.6e-10 38.9 9.1 1.1e-09 38.2 9.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIK42985.1 - 5.9e-06 26.3 8.1 1.2e-05 25.3 8.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Aft1_OSA PF11785.8 KIK42985.1 - 1.6e-05 25.3 1.1 1.6e-05 25.3 1.1 3.5 4 0 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain Spt5_N PF11942.8 KIK42985.1 - 0.89 10.6 11.1 0.74 10.8 7.4 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Nop53 PF07767.11 KIK42985.1 - 0.95 8.8 16.3 2.4 7.4 16.4 1.6 1 1 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) bZIP_Maf PF03131.17 KIK42985.1 - 2.6 8.6 13.5 0.3 11.6 7.9 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor Kp4 PF09044.10 KIK42986.1 - 0.048 13.7 0.2 0.1 12.7 0.2 1.6 1 1 0 1 1 1 0 Kp4 Hexokinase_2 PF03727.16 KIK42987.1 - 1.1e-77 260.7 0.0 1.6e-77 260.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KIK42987.1 - 1.5e-69 233.9 0.0 2e-69 233.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase UPF0270 PF06794.12 KIK42987.1 - 0.024 14.7 0.0 0.064 13.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) Adap_comp_sub PF00928.21 KIK42988.1 - 3.9e-48 164.1 0.0 4.7e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KIK42988.1 - 0.0017 18.3 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain UFC1 PF08694.11 KIK42988.1 - 0.084 12.5 0.0 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 Isochorismatase PF00857.20 KIK42989.1 - 2.5e-23 83.1 0.1 6.5e-23 81.8 0.1 1.6 1 1 0 1 1 1 1 Isochorismatase family DUF1748 PF08520.10 KIK42992.1 - 8.2e-25 86.5 0.0 9e-25 86.4 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) DAD PF02109.16 KIK42993.1 - 9.9e-49 164.2 2.0 1.1e-48 164.0 2.0 1.0 1 0 0 1 1 1 1 DAD family Sod_Fe_C PF02777.18 KIK42994.1 - 2.6e-16 59.6 0.0 1.1e-06 28.7 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Isochorismatase PF00857.20 KIK42995.1 - 1.4e-26 93.7 0.0 2.9e-26 92.7 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family RNA_pol PF00940.19 KIK42996.1 - 2.2e-182 606.5 0.0 3e-182 606.1 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KIK42996.1 - 6.1e-98 328.3 0.5 9.4e-98 327.7 0.5 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.6 KIK42996.1 - 0.032 14.4 0.1 0.11 12.8 0.1 1.9 1 0 0 1 1 1 0 PPR repeat family RPW8 PF05659.11 KIK42997.1 - 0.016 14.9 0.9 0.033 13.9 0.9 1.4 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Cnn_1N PF07989.11 KIK42997.1 - 0.058 13.5 9.2 2.7 8.2 0.1 3.5 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 NPV_P10 PF05531.12 KIK42997.1 - 0.098 13.1 0.4 0.3 11.6 0.4 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 KIK42997.1 - 0.33 11.0 3.1 0.47 10.5 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Phage_GP20 PF06810.11 KIK42997.1 - 5.1 6.9 9.5 4.3 7.1 2.1 2.8 2 1 1 3 3 3 0 Phage minor structural protein GP20 DUF1640 PF07798.11 KIK42997.1 - 5.4 7.0 7.9 2.1 8.4 3.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) CorA PF01544.18 KIK42997.1 - 5.7 6.2 6.3 10 5.4 6.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ADIP PF11559.8 KIK42997.1 - 6.6 6.8 10.2 8.3 6.5 5.6 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 KIK42997.1 - 8.6 5.6 10.5 26 4.0 10.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YlqD PF11068.8 KIK42997.1 - 9 6.7 7.2 2 8.8 2.4 2.1 2 0 0 2 2 2 0 YlqD protein GAS PF13851.6 KIK42997.1 - 9.1 5.6 16.6 0.048 13.0 7.7 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding B12D PF06522.11 KIK42999.1 - 1.1e-12 47.5 0.1 1.5e-12 47.1 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Aldo_ket_red PF00248.21 KIK43000.1 - 1.2e-37 129.7 0.0 1.5e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TPR_1 PF00515.28 KIK43001.1 - 9.9e-31 104.3 19.8 9.3e-08 31.6 0.4 6.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 KIK43001.1 - 2.6e-21 74.0 25.1 2.6e-05 24.0 0.0 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat STI1 PF17830.1 KIK43001.1 - 8.9e-17 60.8 6.8 1.4e-16 60.2 4.9 2.5 3 0 0 3 3 1 1 STI1 domain TPR_8 PF13181.6 KIK43001.1 - 5e-15 54.4 22.7 0.017 15.3 0.0 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 KIK43001.1 - 7.2e-14 52.1 20.8 6.9e-06 26.5 0.1 5.3 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIK43001.1 - 4.5e-13 48.6 3.3 0.0004 20.6 0.2 4.5 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK43001.1 - 9.6e-13 48.2 18.5 3.8e-05 23.9 0.1 5.4 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 KIK43001.1 - 1.1e-12 47.4 16.6 2.7e-08 33.3 0.3 4.6 4 0 0 4 4 4 3 TPR repeat TPR_16 PF13432.6 KIK43001.1 - 2.6e-11 44.0 21.4 8.5e-08 32.7 1.1 4.4 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK43001.1 - 7.4e-09 35.7 21.4 0.0039 17.9 0.1 6.8 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 KIK43001.1 - 6.5e-08 32.2 11.6 1.1 9.2 1.5 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK43001.1 - 5.8e-07 29.1 12.2 0.0032 17.4 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIK43001.1 - 3.8e-06 27.0 7.9 0.00032 20.8 0.0 4.1 3 1 2 5 5 4 3 Tetratricopeptide repeat NARP1 PF12569.8 KIK43001.1 - 6.5e-05 22.0 2.3 6.5e-05 22.0 2.3 2.8 1 1 2 3 3 3 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 KIK43001.1 - 0.0078 16.8 20.8 3 8.7 0.0 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat GerD PF17898.1 KIK43001.1 - 0.038 13.9 3.5 0.11 12.5 3.5 1.9 1 0 0 1 1 1 0 Spore germination GerD central core domain DnaB PF00772.21 KIK43001.1 - 0.039 14.0 2.1 0.071 13.2 0.4 2.2 2 0 0 2 2 2 0 DnaB-like helicase N terminal domain Fis1_TPR_C PF14853.6 KIK43001.1 - 0.13 12.3 8.1 32 4.7 0.1 5.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.20 KIK43001.1 - 0.23 11.8 0.5 14 6.2 0.0 3.3 3 0 0 3 3 3 0 PPR repeat DUF2225 PF09986.9 KIK43001.1 - 1.6 8.4 8.3 0.67 9.6 0.6 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) BTAD PF03704.17 KIK43001.1 - 2.8 8.3 11.6 3.2 8.2 0.5 3.2 3 0 0 3 3 3 0 Bacterial transcriptional activator domain DUF3856 PF12968.7 KIK43001.1 - 3.6 7.7 9.4 4.1 7.5 1.3 3.7 2 2 0 2 2 2 0 Domain of Unknown Function (DUF3856) SPO22 PF08631.10 KIK43001.1 - 5.5 6.4 12.7 1.1 8.7 1.4 3.9 5 0 0 5 5 5 0 Meiosis protein SPO22/ZIP4 like Pkinase PF00069.25 KIK43004.1 - 1.3e-23 83.7 0.0 1.6e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK43004.1 - 9.5e-12 44.7 0.0 1.2e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK43004.1 - 3.5e-08 32.6 0.1 4.8e-08 32.2 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KIK43004.1 - 0.0019 17.8 0.1 0.0031 17.1 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIK43004.1 - 0.012 15.6 1.3 0.3 11.0 0.2 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KIK43004.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dimer_Tnp_hAT PF05699.14 KIK43008.1 - 2.3e-14 53.0 0.0 3.5e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HSP70 PF00012.20 KIK43009.1 - 2.7e-22 78.7 0.0 2.9e-22 78.6 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Peptidase_M22 PF00814.25 KIK43011.1 - 1.9e-34 119.6 0.0 2.1e-19 70.3 0.0 2.3 1 1 1 2 2 2 2 Glycoprotease family Ribosomal_S7 PF00177.21 KIK43012.1 - 1.7e-19 69.9 2.2 2.1e-19 69.6 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Pkinase PF00069.25 KIK43014.1 - 2.6e-64 217.1 0.0 3.1e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK43014.1 - 2e-27 96.1 0.0 3.1e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK43014.1 - 4.6e-06 26.2 0.0 6.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK43014.1 - 0.00031 20.2 0.0 0.00057 19.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIK43014.1 - 0.00097 18.8 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIK43014.1 - 0.0032 17.4 0.3 1.3 8.9 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK43014.1 - 0.032 13.2 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Sec2p PF06428.11 KIK43015.1 - 2.8e-13 49.6 12.3 2.8e-13 49.6 12.3 2.8 3 1 0 3 3 3 1 GDP/GTP exchange factor Sec2p Herpes_UL6 PF01763.16 KIK43015.1 - 2.1 6.8 8.1 1.2 7.6 5.2 1.9 1 1 1 2 2 2 0 Herpesvirus UL6 like NTF2 PF02136.20 KIK43016.1 - 4.4e-29 101.5 0.2 6.3e-29 101.0 0.2 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KIK43016.1 - 2.7e-08 33.5 0.1 5.5e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIK43016.1 - 0.015 15.1 0.1 0.027 14.3 0.1 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 KIK43016.1 - 0.028 14.5 0.0 0.063 13.3 0.0 1.5 1 1 0 1 1 1 0 RNA binding motif Het-C PF07217.11 KIK43017.1 - 2.8e-217 722.7 0.0 3.6e-217 722.4 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DEAD PF00270.29 KIK43019.1 - 1.6e-41 142.0 0.0 6.4e-41 140.0 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK43019.1 - 1.7e-27 96.0 0.0 7.7e-26 90.6 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK43019.1 - 3.6e-05 23.8 0.0 8.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2554 PF10829.8 KIK43019.1 - 0.087 13.2 0.1 0.18 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2554) F-box-like PF12937.7 KIK43020.1 - 0.049 13.5 0.0 0.19 11.7 0.0 2.1 1 1 0 1 1 1 0 F-box-like LRR19-TM PF15176.6 KIK43020.1 - 0.23 11.5 0.4 19 5.3 0.1 2.5 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain Terpene_synth_C PF03936.16 KIK43021.1 - 1.1e-07 31.5 0.0 1.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain SPOB_ab PF14682.6 KIK43021.1 - 0.0026 17.8 0.1 0.006 16.6 0.1 1.6 1 0 0 1 1 1 1 Sporulation initiation phospho-transferase B, C-terminal FadR_C PF07840.12 KIK43021.1 - 0.14 12.1 0.2 0.23 11.4 0.2 1.3 1 0 0 1 1 1 0 FadR C-terminal domain MFS_1 PF07690.16 KIK43022.1 - 8.3e-26 90.7 28.8 4.9e-20 71.8 8.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK43022.1 - 5.7e-07 28.7 8.4 5.7e-07 28.7 8.4 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KIK43022.1 - 0.11 11.3 22.0 0.1 11.4 0.5 3.2 2 1 1 3 3 3 0 MFS_1 like family DASH_Dad3 PF08656.10 KIK43023.1 - 0.011 15.9 1.7 1.4 9.1 0.1 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad3 MTP18 PF10558.9 KIK43023.1 - 0.16 12.0 0.1 0.28 11.1 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) T2SSM PF04612.12 KIK43023.1 - 1.9 8.5 7.1 0.93 9.5 0.1 3.3 4 0 0 4 4 4 0 Type II secretion system (T2SS), protein M Formyl_trans_N PF00551.19 KIK43024.1 - 2.4e-19 69.8 0.0 3.5e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KIK43024.1 - 4.8e-11 42.8 0.0 7.9e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain XPG_N PF00752.17 KIK43025.1 - 1.9e-25 89.3 0.0 4.4e-25 88.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KIK43025.1 - 1.7e-24 85.9 0.0 3.4e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 KIK43025.1 - 1e-06 29.3 0.0 7.9e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.7 KIK43025.1 - 5.6e-05 22.7 0.0 8.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing TPR_8 PF13181.6 KIK43025.1 - 0.0091 16.1 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat HHH_5 PF14520.6 KIK43025.1 - 0.018 15.6 0.0 0.19 12.3 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix domain TPR_2 PF07719.17 KIK43025.1 - 0.14 12.3 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C2H2 PF00096.26 KIK43027.1 - 2e-11 43.7 9.0 5.4e-06 26.6 0.9 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK43027.1 - 5e-08 33.1 8.1 0.0001 22.8 0.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK43027.1 - 2.5e-06 27.7 9.7 1.4e-05 25.3 0.6 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 KIK43027.1 - 5.1e-05 23.5 5.1 0.00038 20.8 0.3 2.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KIK43027.1 - 0.00015 21.7 0.2 0.00015 21.7 0.2 2.8 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK43027.1 - 0.00031 20.9 3.8 0.22 11.9 0.1 2.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding PIG-P PF08510.12 KIK43028.1 - 8.5e-33 112.8 5.3 9.8e-33 112.6 5.3 1.0 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 KIK43028.1 - 0.19 12.0 12.5 0.63 10.4 12.5 1.8 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) 5-FTHF_cyc-lig PF01812.20 KIK43029.1 - 5.8e-45 153.4 0.0 6.5e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family RecA PF00154.21 KIK43030.1 - 3.6e-06 26.6 0.0 7.5e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KIK43030.1 - 0.00029 20.3 0.0 0.00054 19.4 0.0 1.4 1 0 0 1 1 1 1 KaiC DUF5497 PF17601.2 KIK43030.1 - 0.034 14.5 0.1 0.062 13.6 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5497) HHH_5 PF14520.6 KIK43030.1 - 0.099 13.3 0.1 0.24 12.0 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain RRM_1 PF00076.22 KIK43031.1 - 1.3e-29 101.8 0.0 1.2e-10 41.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIK43031.1 - 3.8e-05 23.3 0.0 0.028 14.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1010 PF06231.11 KIK43032.1 - 0.33 11.5 2.8 8.1 7.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1010) Glyco_hydro_16 PF00722.21 KIK43033.1 - 6.3e-39 133.3 3.3 9.6e-39 132.7 3.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MutS_V PF00488.21 KIK43034.1 - 4e-66 222.7 0.1 5.3e-65 219.0 0.1 2.4 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KIK43034.1 - 1e-35 123.7 1.2 1.9e-35 122.9 0.2 2.0 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 KIK43034.1 - 4.6e-33 113.8 0.0 9.8e-33 112.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KIK43034.1 - 9.7e-12 45.3 1.2 4.5e-11 43.2 0.2 2.5 2 1 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KIK43034.1 - 0.0002 21.6 0.1 0.00058 20.1 0.1 1.9 1 0 0 1 1 1 1 MutS family domain IV ABC_tran_CTD PF16326.5 KIK43034.1 - 2.2 8.6 4.7 41 4.5 0.3 3.4 3 0 0 3 3 3 0 ABC transporter C-terminal domain CDC45 PF02724.14 KIK43034.1 - 6.6 4.9 10.9 11 4.2 10.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF667 PF05018.13 KIK43035.1 - 9.2e-22 77.7 0.0 9.5e-11 41.8 0.0 3.3 3 1 0 3 3 3 3 Protein of unknown function (DUF667) PDEase_I PF00233.19 KIK43036.1 - 2.1e-53 181.5 0.0 5.7e-53 180.1 0.0 1.7 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase UL42 PF17638.2 KIK43038.1 - 0.82 9.7 4.2 1.4 9.0 4.2 1.5 1 1 0 1 1 1 0 HCMV UL42 Abhydrolase_1 PF00561.20 KIK43039.1 - 1.3e-18 67.6 0.1 1.1e-17 64.6 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK43039.1 - 2.9e-14 54.2 13.9 2.9e-13 51.0 13.9 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK43039.1 - 1.7e-05 24.2 0.0 9.1e-05 21.8 0.1 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KIK43039.1 - 0.08 11.8 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme SIS PF01380.22 KIK43040.1 - 2e-62 208.9 0.2 3.6e-34 117.4 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KIK43040.1 - 3.2e-15 56.5 0.0 6.5e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KIK43040.1 - 4.2e-10 39.6 0.0 9.6e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KIK43040.1 - 2.1e-05 23.6 0.0 3.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 KIK43040.1 - 0.088 12.8 0.0 1.8 8.6 0.0 2.5 1 1 1 2 2 2 0 SIS domain SLATT_fungal PF18142.1 KIK43042.1 - 1.3e-40 138.1 0.3 1.7e-40 137.7 0.3 1.1 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Npa1 PF11707.8 KIK43042.1 - 0.052 12.9 0.0 0.064 12.6 0.0 1.1 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal PRA-CH PF01502.18 KIK43043.1 - 0.043 13.6 0.6 0.061 13.1 0.5 1.3 1 1 0 1 1 1 0 Phosphoribosyl-AMP cyclohydrolase UbiA PF01040.18 KIK43045.1 - 2.8e-42 144.8 13.3 3.5e-42 144.5 13.3 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family polyprenyl_synt PF00348.17 KIK43046.1 - 3.1e-56 190.3 0.0 3.8e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Fungal_lectin PF07938.12 KIK43047.1 - 6.2e-17 61.9 0.6 3.6e-16 59.4 0.6 1.8 1 1 0 1 1 1 1 Fungal fucose-specific lectin Fungal_lectin PF07938.12 KIK43049.1 - 4.5e-14 52.5 0.3 1.1e-13 51.3 0.3 1.5 1 1 0 1 1 1 1 Fungal fucose-specific lectin Med16 PF11635.8 KIK43049.1 - 0.00013 20.1 0.1 0.00017 19.7 0.1 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 HSP70 PF00012.20 KIK43050.1 - 0.16 10.1 0.0 3.1 5.9 0.1 2.8 2 1 0 2 2 2 0 Hsp70 protein F-box-like PF12937.7 KIK43051.1 - 0.0086 15.9 0.1 0.02 14.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK43051.1 - 0.012 15.5 0.2 0.039 13.8 0.0 2.0 2 0 0 2 2 2 0 F-box domain zf-C2H2 PF00096.26 KIK43052.1 - 0.0024 18.2 4.1 0.014 15.9 1.6 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type IBR PF01485.21 KIK43052.1 - 0.0046 17.2 2.6 0.0096 16.1 2.6 1.6 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain DUF1275 PF06912.11 KIK43053.1 - 1.3e-31 110.1 19.6 1.6e-31 109.8 19.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Golgin_A5 PF09787.9 KIK43054.1 - 0.012 15.1 25.4 0.018 14.5 25.4 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 CENP-F_leu_zip PF10473.9 KIK43054.1 - 0.066 13.2 31.9 0.13 12.3 2.6 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 KIK43054.1 - 0.13 11.9 24.6 0.19 11.3 24.6 1.2 1 0 0 1 1 1 0 Intermediate filament protein NiFeSe_Hases PF00374.19 KIK43054.1 - 0.17 10.7 2.5 0.29 10.0 2.5 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase HAUS-augmin3 PF14932.6 KIK43054.1 - 0.66 9.5 25.1 2 7.9 24.6 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 CdvA PF18822.1 KIK43054.1 - 1.2 8.9 17.4 0.35 10.7 12.9 2.2 1 1 1 2 2 2 0 CdvA-like coiled-coil domain SOAR PF16533.5 KIK43054.1 - 1.4 9.0 12.8 1.1 9.2 10.3 2.2 1 1 0 1 1 1 0 STIM1 Orai1-activating region LMBR1 PF04791.16 KIK43054.1 - 4.7 6.0 8.3 6.8 5.5 8.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein ATG16 PF08614.11 KIK43054.1 - 4.8 7.3 38.2 8.4 6.6 30.1 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Macoilin PF09726.9 KIK43055.1 - 5.8e-05 21.9 16.5 7.4e-05 21.5 16.5 1.1 1 0 0 1 1 1 1 Macoilin family Fez1 PF06818.15 KIK43055.1 - 0.00011 22.8 13.2 0.00011 22.8 13.2 1.7 2 0 0 2 2 2 1 Fez1 Phlebovirus_NSM PF07246.11 KIK43055.1 - 0.00077 18.9 4.2 0.0014 18.1 4.2 1.3 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M FPP PF05911.11 KIK43055.1 - 0.0015 16.9 12.2 0.0027 16.0 12.2 1.3 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Golgin_A5 PF09787.9 KIK43055.1 - 0.023 14.2 10.0 0.048 13.1 10.0 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 Atg14 PF10186.9 KIK43055.1 - 0.051 12.7 8.0 0.089 11.9 8.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KIK43055.1 - 0.1 12.7 10.3 0.28 11.3 10.3 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 KIK43055.1 - 0.25 11.3 16.2 0.53 10.3 16.2 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RasGAP_C PF03836.15 KIK43055.1 - 0.32 11.2 5.7 0.072 13.2 1.3 2.1 2 0 0 2 2 2 0 RasGAP C-terminus ADIP PF11559.8 KIK43055.1 - 0.35 11.0 18.9 1 9.4 10.5 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 KIK43055.1 - 0.38 11.3 22.3 0.33 11.5 14.2 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region Spc7 PF08317.11 KIK43055.1 - 0.39 9.5 13.4 0.74 8.6 13.4 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5094 PF17015.5 KIK43055.1 - 1.3 9.1 9.7 0.026 14.6 2.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) HHH_9 PF17674.1 KIK43055.1 - 1.8 9.5 4.1 2 9.4 0.2 2.9 2 1 0 2 2 2 0 HHH domain UPF0231 PF06062.11 KIK43055.1 - 3.2 8.1 5.7 2.5 8.4 2.4 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0231) DUF3450 PF11932.8 KIK43055.1 - 6.3 6.0 16.2 30 3.8 16.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Csm1_N PF18504.1 KIK43055.1 - 6.8 7.1 13.4 7.5 7.0 1.0 3.2 2 1 1 3 3 3 0 Csm1 N-terminal domain TBCA PF02970.16 KIK43055.1 - 7.6 6.9 10.3 1.2 9.5 4.9 2.3 1 1 1 2 2 2 0 Tubulin binding cofactor A Gp58 PF07902.11 KIK43057.1 - 0.0097 14.2 7.5 0.0097 14.3 6.5 1.5 2 0 0 2 2 2 1 gp58-like protein DUF5082 PF16888.5 KIK43057.1 - 0.028 14.7 17.9 0.17 12.2 7.8 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) DNA_repr_REX1B PF14966.6 KIK43057.1 - 0.12 13.0 14.6 2.2 9.0 10.5 3.5 3 1 2 5 5 5 0 DNA repair REX1-B Peptidase_S46 PF10459.9 KIK43057.1 - 0.17 10.5 15.8 0.24 10.0 15.8 1.2 1 0 0 1 1 1 0 Peptidase S46 APG6_N PF17675.1 KIK43057.1 - 0.41 11.2 34.9 0.2 12.2 32.4 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region Spc7 PF08317.11 KIK43057.1 - 0.72 8.7 25.4 1.3 7.8 25.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 KIK43057.1 - 2.9 6.9 19.6 4.6 6.2 19.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 KIK43057.1 - 4.7 6.7 16.7 9.3 5.7 16.7 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit PriA_C PF18074.1 KIK43057.1 - 4.7 8.1 5.7 19 6.2 5.6 2.1 1 1 0 1 1 1 0 Primosomal protein N C-terminal domain HSP70 PF00012.20 KIK43060.1 - 0.043 12.0 0.1 0.17 10.1 0.0 2.0 2 1 0 2 2 2 0 Hsp70 protein Mito_carr PF00153.27 KIK43061.1 - 6.9e-55 183.0 2.1 2.1e-18 66.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RNase_T PF00929.24 KIK43062.1 - 9.1e-13 49.1 0.0 1.4e-12 48.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KIK43062.1 - 0.058 13.1 0.0 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 3'-5' exonuclease G-patch PF01585.23 KIK43063.1 - 2.5e-07 30.5 0.9 2.5e-07 30.5 0.9 2.8 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.7 KIK43063.1 - 0.034 14.2 0.4 0.034 14.2 0.4 4.4 4 1 0 4 4 4 0 G-patch domain AF-4 PF05110.13 KIK43063.1 - 0.1 10.7 35.5 0.078 11.1 6.7 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Abhydrolase_1 PF00561.20 KIK43064.1 - 3.8e-24 85.7 0.4 5.1e-24 85.3 0.4 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KIK43064.1 - 1.7e-23 82.0 0.1 3.2e-23 81.1 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region FSH1 PF03959.13 KIK43064.1 - 0.00086 19.0 0.0 0.19 11.3 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KIK43064.1 - 0.0025 17.1 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 PB1 PF00564.24 KIK43065.1 - 2.2e-13 49.9 0.0 3.8e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_2 PF07719.17 KIK43065.1 - 8.5e-08 31.8 3.2 0.33 11.2 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIK43065.1 - 2.7e-07 30.1 4.4 0.0089 15.8 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK43065.1 - 2.5e-05 24.1 3.9 0.0017 18.4 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK43065.1 - 0.00091 18.9 0.4 0.0062 16.2 0.0 2.7 2 1 0 2 2 2 1 TPR repeat TPR_12 PF13424.6 KIK43065.1 - 0.00098 19.4 0.8 0.11 12.9 0.2 2.9 2 1 2 4 4 4 2 Tetratricopeptide repeat VPS28 PF03997.12 KIK43065.1 - 0.091 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 VPS28 protein TPR_16 PF13432.6 KIK43065.1 - 0.14 12.8 0.2 0.14 12.8 0.2 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat IGPS PF00218.21 KIK43069.1 - 8.3e-82 274.2 0.0 1.8e-81 273.1 0.0 1.5 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 KIK43069.1 - 2e-40 138.6 0.0 3.8e-40 137.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.22 KIK43069.1 - 3.2e-36 124.9 0.1 1.3e-12 47.9 0.0 5.0 4 1 0 4 4 4 4 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 KIK43069.1 - 0.0029 17.4 0.4 0.014 15.2 0.4 1.9 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 KIK43069.1 - 0.011 15.5 0.3 0.11 12.3 0.1 2.3 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain Fic PF02661.18 KIK43071.1 - 3.8e-12 46.9 0.0 9.1e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Fic/DOC family MIF4G PF02854.19 KIK43077.1 - 4.8e-57 193.0 0.4 4.8e-57 193.0 0.4 1.6 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.8 KIK43077.1 - 1.3e-17 63.7 0.0 3.6e-17 62.3 0.0 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.17 KIK43077.1 - 8.6e-05 22.5 0.2 0.0003 20.8 0.0 2.0 2 0 0 2 2 2 1 MA3 domain Macoilin PF09726.9 KIK43077.1 - 4.7 5.6 25.6 0.25 9.8 18.3 2.3 2 0 0 2 2 2 0 Macoilin family MIF4G PF02854.19 KIK43078.1 - 6.4e-53 179.5 0.5 1e-52 178.9 0.5 1.2 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 KIK43078.1 - 3.5e-06 27.0 0.1 3.8e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 MA3 domain eIF_4G1 PF12152.8 KIK43080.1 - 1.4e-18 66.8 0.0 2e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Phage_integrase PF00589.22 KIK43085.1 - 0.051 13.4 0.0 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 Phage integrase family XPG_I PF00867.18 KIK43086.1 - 3.7e-17 62.5 0.1 5.4e-17 61.9 0.1 1.3 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KIK43086.1 - 0.0029 18.1 0.0 0.0057 17.1 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain BTB PF00651.31 KIK43090.1 - 1.6e-05 25.0 0.0 2.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Calreticulin PF00262.18 KIK43092.1 - 0.016 14.1 0.1 0.022 13.6 0.1 1.2 1 0 0 1 1 1 0 Calreticulin family Fzo_mitofusin PF04799.13 KIK43092.1 - 0.083 12.4 0.7 0.17 11.4 0.7 1.5 1 0 0 1 1 1 0 fzo-like conserved region AA_permease PF00324.21 KIK43094.1 - 2e-123 412.5 39.4 2.4e-123 412.3 39.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK43094.1 - 1.7e-31 109.5 40.9 2.1e-31 109.2 40.9 1.0 1 0 0 1 1 1 1 Amino acid permease A_deaminase_N PF08451.11 KIK43095.1 - 0.00074 19.8 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal 7TM_GPCR_Srx PF10328.9 KIK43095.1 - 0.055 13.1 0.3 0.076 12.6 0.3 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Ferric_reduct PF01794.19 KIK43098.1 - 2.2e-20 73.0 5.2 2.2e-20 73.0 5.2 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KIK43098.1 - 4.2e-17 62.7 0.0 7.5e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KIK43098.1 - 7.5e-17 61.4 0.0 1.6e-10 41.1 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 KIK43098.1 - 0.013 16.1 0.0 0.36 11.5 0.0 2.3 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Penaeidin PF05927.11 KIK43100.1 - 0.075 13.8 0.0 0.079 13.7 0.0 1.1 1 0 0 1 1 1 0 Penaeidin Ta0938 PF11494.8 KIK43101.1 - 0.041 14.2 0.0 0.053 13.8 0.0 1.2 1 0 0 1 1 1 0 Ta0938 PhoLip_ATPase_C PF16212.5 KIK43106.1 - 1.3e-73 247.8 32.0 1.3e-73 247.8 32.0 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KIK43106.1 - 4.6e-22 77.5 4.2 1.5e-21 75.8 0.9 2.7 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KIK43106.1 - 7.8e-12 45.1 0.0 1.8e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KIK43106.1 - 8.2e-12 45.9 1.5 1.4e-05 25.5 0.7 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KIK43106.1 - 1.7e-06 27.7 6.6 4.2e-06 26.4 0.0 3.5 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KIK43106.1 - 0.0077 16.0 0.0 0.049 13.4 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4134 PF13572.6 KIK43107.1 - 0.068 13.5 4.3 0.19 12.0 4.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4134) DUF2101 PF09874.9 KIK43107.1 - 0.075 12.7 10.0 0.044 13.5 4.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) DUF4231 PF14015.6 KIK43107.1 - 8 7.0 8.5 81 3.8 7.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) F-box-like PF12937.7 KIK43108.1 - 2.3e-06 27.4 0.1 6.8e-06 25.9 0.1 1.9 1 0 0 1 1 1 1 F-box-like Fungal_trans PF04082.18 KIK43109.1 - 1.1e-21 77.1 0.0 2.3e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK43109.1 - 4.5e-10 39.5 10.8 9.2e-10 38.5 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp PF00026.23 KIK43110.1 - 5.8e-31 108.1 0.0 3.3e-18 66.2 1.9 2.4 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK43110.1 - 0.00014 22.2 1.7 0.002 18.4 1.7 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK43110.1 - 0.074 13.7 2.0 11 6.8 0.6 3.9 3 1 0 3 3 3 0 Aspartyl protease Mito_carr PF00153.27 KIK43111.1 - 2e-52 175.1 0.1 3.7e-17 62.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein adh_short_C2 PF13561.6 KIK43113.1 - 3.3e-59 200.3 0.3 4.1e-59 200.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK43113.1 - 1.1e-52 178.4 0.8 1.4e-52 178.0 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK43113.1 - 4.3e-13 49.6 0.3 6.1e-13 49.1 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK43113.1 - 0.093 12.2 0.2 0.44 10.0 0.2 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_6 PF08030.12 KIK43114.1 - 2.9e-21 76.2 0.0 5.2e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KIK43114.1 - 3.2e-20 72.5 7.3 3.2e-20 72.5 7.3 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KIK43114.1 - 2e-16 60.0 0.0 4.2e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 KIK43114.1 - 0.0038 17.8 0.0 0.63 10.7 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Pex19 PF04614.12 KIK43115.1 - 2.1e-56 191.5 7.9 2.1e-56 191.5 7.9 1.7 1 1 1 2 2 2 1 Pex19 protein family AAA_16 PF13191.6 KIK43118.1 - 2.2e-05 24.9 0.1 2.2e-05 24.9 0.1 2.7 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 KIK43118.1 - 0.00012 22.0 1.0 0.00064 19.7 0.1 2.7 3 1 0 3 3 3 1 NACHT domain Parvo_NS1 PF01057.17 KIK43118.1 - 0.00026 20.2 0.3 0.0006 19.0 0.0 1.7 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.6 KIK43118.1 - 0.00045 20.5 0.1 0.0037 17.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KIK43118.1 - 0.00061 19.8 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KIK43118.1 - 0.00085 18.6 0.0 0.0024 17.1 0.0 1.8 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 KIK43118.1 - 0.0075 16.7 0.0 0.03 14.8 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KIK43118.1 - 0.015 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain APS_kinase PF01583.20 KIK43118.1 - 0.04 13.8 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Sigma54_activ_2 PF14532.6 KIK43118.1 - 0.047 13.8 0.1 2.1 8.5 0.0 2.9 2 1 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KIK43118.1 - 0.06 13.7 0.0 0.19 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 KIK43118.1 - 0.12 11.8 0.1 0.64 9.4 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_PrkA PF08298.11 KIK43118.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain Rad17 PF03215.15 KIK43118.1 - 0.13 12.2 0.0 2.5 8.0 0.0 2.8 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_30 PF13604.6 KIK43118.1 - 0.16 11.7 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KIK43119.1 - 1.7e-05 25.5 0.0 3.2e-05 24.6 0.0 1.5 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF4875 PF16175.5 KIK43119.1 - 0.036 14.2 0.1 0.042 14.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4875) ANAPC4_WD40 PF12894.7 KIK43119.1 - 0.043 14.1 0.0 0.045 14.0 0.0 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK43120.1 - 7.2e-07 29.8 0.0 5.7e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43120.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK43121.1 - 4.7e-30 103.2 8.6 1.3e-08 35.3 0.5 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43121.1 - 2.8e-08 33.9 0.3 0.24 11.7 0.0 4.2 2 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK43121.1 - 2e-06 26.8 2.3 0.017 13.8 0.2 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK43121.1 - 0.00092 18.6 0.0 0.091 12.1 0.0 2.5 2 0 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 KIK43121.1 - 0.0045 16.0 0.2 3 6.7 0.1 3.3 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK43121.1 - 0.012 15.6 0.1 24 5.0 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 KIK43125.1 - 1.1e-28 98.9 7.3 5.8e-08 33.3 0.4 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43125.1 - 3.4e-07 30.5 0.1 0.095 13.0 0.0 3.6 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK43125.1 - 0.0024 16.6 0.2 0.072 11.7 0.0 2.3 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK43125.1 - 0.011 14.8 0.1 3 6.7 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HARP PF07443.13 KIK43125.1 - 0.14 11.9 0.6 18 5.1 0.0 3.5 4 0 0 4 4 4 0 HepA-related protein (HARP) WD40 PF00400.32 KIK43128.1 - 5.8e-27 93.4 6.8 9.6e-07 29.4 0.5 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43128.1 - 2.4e-06 27.8 0.1 0.043 14.1 0.0 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK43128.1 - 0.00018 20.3 1.5 0.066 11.8 0.0 3.0 3 0 0 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.12 KIK43128.1 - 0.0071 16.3 0.1 14 5.7 0.0 4.0 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat WD40 PF00400.32 KIK43131.1 - 4.6e-25 87.4 4.7 3.1e-08 34.1 0.3 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43131.1 - 2.7e-06 27.6 0.3 0.88 9.9 0.0 4.6 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK43131.1 - 0.00071 18.6 0.5 0.21 10.5 0.0 2.7 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK43131.1 - 0.0018 17.0 0.2 0.012 14.3 0.0 2.3 2 1 2 4 4 4 1 Nucleoporin Nup120/160 Pkinase PF00069.25 KIK43133.1 - 5.7e-27 94.7 0.0 9.1e-13 48.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK43133.1 - 2.2e-06 27.1 0.1 0.00053 19.4 0.1 2.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KIK43133.1 - 0.051 12.5 0.1 0.075 12.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase LRR_4 PF12799.7 KIK43134.1 - 0.0037 17.6 9.5 0.25 11.8 0.3 5.2 3 1 2 5 5 5 1 Leucine Rich repeats (2 copies) p450 PF00067.22 KIK43136.1 - 3.7e-64 217.2 0.0 4.3e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_4 PF07993.12 KIK43137.1 - 3.1e-33 115.0 0.0 5e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIK43137.1 - 2.6e-27 95.5 0.0 4.3e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KIK43137.1 - 8.3e-11 41.8 0.0 1.4e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIK43137.1 - 0.00039 20.7 0.0 0.0015 18.9 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 KIK43137.1 - 0.0045 16.4 0.0 0.0069 15.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase GH3 PF03321.13 KIK43137.1 - 0.09 11.6 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 GH3 auxin-responsive promoter NAD_binding_10 PF13460.6 KIK43137.1 - 0.19 11.6 0.0 28 4.5 0.0 2.6 2 0 0 2 2 2 0 NAD(P)H-binding MFS_1 PF07690.16 KIK43138.1 - 7.3e-26 90.9 26.9 7.3e-26 90.9 26.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.11 KIK43138.1 - 0.96 9.8 0.0 0.96 9.8 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) Lon_C PF05362.13 KIK43140.1 - 4.2e-68 228.9 0.1 7.1e-68 228.2 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KIK43140.1 - 1.1e-34 120.2 0.0 2.1e-34 119.2 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KIK43140.1 - 3.6e-22 79.2 0.0 9.7e-22 77.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIK43140.1 - 2.4e-08 34.1 0.0 4.4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KIK43140.1 - 4.4e-06 26.5 0.0 8.7e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 KIK43140.1 - 2.2e-05 23.6 0.0 4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_2 PF07724.14 KIK43140.1 - 2.5e-05 24.5 0.0 5.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KIK43140.1 - 0.00018 21.3 0.0 0.00079 19.2 0.0 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KIK43140.1 - 0.00019 21.9 0.0 0.00061 20.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK43140.1 - 0.00029 21.1 0.0 0.0037 17.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIK43140.1 - 0.0012 19.4 0.5 0.0037 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KIK43140.1 - 0.0041 16.9 0.0 0.0087 15.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 KIK43140.1 - 0.0046 17.0 0.0 0.014 15.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 KIK43140.1 - 0.009 16.4 0.1 0.092 13.1 0.0 2.3 2 0 0 2 2 2 1 RNA helicase RsgA_GTPase PF03193.16 KIK43140.1 - 0.015 15.2 0.1 0.14 12.0 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase SKI PF01202.22 KIK43140.1 - 0.036 14.2 0.1 0.11 12.7 0.0 1.9 2 0 0 2 2 1 0 Shikimate kinase AAA_30 PF13604.6 KIK43140.1 - 0.047 13.4 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KIK43140.1 - 0.052 12.7 0.7 0.21 10.7 0.1 2.2 3 0 0 3 3 3 0 TIP49 P-loop domain MCM PF00493.23 KIK43140.1 - 0.075 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain NTPase_1 PF03266.15 KIK43140.1 - 0.086 12.7 0.2 0.54 10.2 0.1 2.3 2 1 1 3 3 3 0 NTPase NB-ARC PF00931.22 KIK43140.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 KIK43140.1 - 0.12 12.9 0.1 0.39 11.2 0.1 1.8 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KIK43140.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIK43140.1 - 0.13 12.1 0.9 10 5.9 0.0 2.8 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KIK43140.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KIK43140.1 - 0.18 11.3 0.0 0.39 10.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region SPX PF03105.19 KIK43140.1 - 1.1 9.2 10.8 2.1 8.2 3.7 2.3 2 0 0 2 2 2 0 SPX domain PrpF PF04303.13 KIK43141.1 - 9.4e-81 271.6 0.1 1.2e-80 271.3 0.1 1.1 1 0 0 1 1 1 1 PrpF protein RsgI_N PF12791.7 KIK43141.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Anti-sigma factor N-terminus CDC27 PF09507.10 KIK43144.1 - 3.9e-36 125.4 60.3 1.2e-29 103.9 41.0 3.0 1 1 1 2 2 2 2 DNA polymerase subunit Cdc27 Peptidase_U57 PF05582.12 KIK43144.1 - 0.17 11.1 5.1 0.59 9.3 1.7 2.6 1 1 1 2 2 2 0 YabG peptidase U57 DUF4919 PF16266.5 KIK43144.1 - 0.44 10.5 2.5 8.3 6.3 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) DUF4766 PF15973.5 KIK43145.1 - 0.37 11.4 9.5 0.86 10.2 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4766) PS_Dcarbxylase PF02666.15 KIK43147.1 - 1.6e-58 197.6 0.0 2.4e-58 197.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KIK43147.1 - 2e-29 101.9 0.0 1.5e-17 63.8 0.0 2.8 3 0 0 3 3 3 2 C2 domain EF-hand_7 PF13499.6 KIK43147.1 - 0.088 13.3 0.1 0.27 11.7 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 KIK43147.1 - 0.16 12.0 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain HET PF06985.11 KIK43148.1 - 9.5e-06 26.0 0.3 3.1e-05 24.4 0.0 1.8 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) CRPA PF05745.11 KIK43148.1 - 0.19 11.7 0.1 0.4 10.7 0.1 1.5 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Pkinase PF00069.25 KIK43151.1 - 3.9e-25 88.7 0.0 4.3e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK43151.1 - 2.8e-13 49.8 0.0 3e-13 49.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK43151.1 - 0.0012 17.7 0.0 0.0013 17.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIK43151.1 - 0.0084 15.5 0.0 0.01 15.2 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIK43151.1 - 0.01 15.2 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KIK43151.1 - 0.012 14.6 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KIK43151.1 - 0.039 13.9 0.1 0.049 13.5 0.1 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KIK43152.1 - 0.16 11.3 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Sod_Fe_C PF02777.18 KIK43154.1 - 3.9e-33 113.7 0.0 6.9e-33 112.9 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KIK43154.1 - 3e-31 107.7 3.5 4.4e-31 107.2 1.8 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HET PF06985.11 KIK43155.1 - 6.7e-05 23.3 1.1 0.0002 21.7 0.3 1.9 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Nbl1_Borealin_N PF10444.9 KIK43158.1 - 0.11 12.1 0.6 0.18 11.4 0.6 1.3 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal WD40 PF00400.32 KIK43160.1 - 2.4e-30 104.1 6.4 7.7e-08 32.9 0.4 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43160.1 - 1.1e-11 44.9 0.0 0.0073 16.6 0.0 4.7 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK43160.1 - 7.4e-05 21.9 0.0 0.28 10.1 0.0 2.3 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK43160.1 - 0.00012 20.9 0.3 0.065 11.9 0.0 2.4 3 0 0 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK43160.1 - 0.0029 17.0 0.0 0.01 15.2 0.0 1.8 2 0 0 2 2 2 1 WD40-like domain Plavaka PF18759.1 KIK43163.1 - 3.7e-30 105.3 0.0 1.3e-25 90.3 0.0 2.2 1 1 1 2 2 2 2 Plavaka transposase IBD PF10416.9 KIK43163.1 - 0.043 13.8 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD PAS_4 PF08448.10 KIK43163.1 - 0.047 13.9 0.0 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 PAS fold BSP PF04450.12 KIK43164.1 - 1.7e-60 204.3 0.0 2e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria SprT-like PF10263.9 KIK43164.1 - 0.025 14.5 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 SprT-like family GpcrRhopsn4 PF10192.9 KIK43166.1 - 0.014 14.8 0.4 0.018 14.5 0.4 1.1 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain DUF1082 PF06449.11 KIK43167.1 - 0.16 11.8 1.0 20 5.1 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial domain of unknown function (DUF1082) SlyX PF04102.12 KIK43173.1 - 0.032 14.9 0.1 0.083 13.5 0.0 1.7 2 0 0 2 2 2 0 SlyX Pre-SET PF05033.16 KIK43174.1 - 1.7e-19 70.5 1.1 1.7e-19 70.5 1.1 2.5 2 1 0 2 2 2 1 Pre-SET motif SET PF00856.28 KIK43174.1 - 4.3e-16 59.8 0.2 1.2e-15 58.3 0.2 1.8 1 1 0 1 1 1 1 SET domain Glyco_hydro_20 PF00728.22 KIK43175.1 - 9.6e-89 298.2 0.0 1.2e-88 297.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KIK43175.1 - 9.9e-13 48.9 0.0 1.9e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KIK43175.1 - 2.2e-06 28.5 0.2 4.8e-06 27.4 0.2 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 WD40 PF00400.32 KIK43176.1 - 0.0097 16.7 1.9 2.4 9.1 0.0 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat EB1 PF03271.17 KIK43180.1 - 6.2e-17 61.6 2.9 1.3e-16 60.5 2.9 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 KIK43180.1 - 2.1e-05 24.7 0.3 4.3e-05 23.7 0.3 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.16 KIK43180.1 - 0.1 11.1 0.1 0.13 10.8 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like zf-C4H2 PF10146.9 KIK43180.1 - 0.25 11.6 1.4 0.42 10.9 1.4 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Glyco_hydro_15 PF00723.21 KIK43181.1 - 4.2e-41 141.2 0.0 5.7e-40 137.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 MFS_1 PF07690.16 KIK43181.1 - 3.3e-27 95.4 47.9 6.4e-27 94.4 45.3 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily CPBP PF02517.16 KIK43183.1 - 4.2e-18 65.5 6.0 4.2e-18 65.5 6.0 2.5 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease F1F0-ATPsyn_F PF10791.9 KIK43184.1 - 1.5e-30 105.5 0.0 1.7e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 KIK43184.1 - 0.016 15.6 0.0 0.022 15.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f MCM_OB PF17207.3 KIK43186.1 - 0.023 14.6 2.0 0.028 14.3 2.0 1.2 1 0 0 1 1 1 0 MCM OB domain Mucin_bdg PF03272.13 KIK43187.1 - 0.16 12.0 0.1 0.18 11.9 0.1 1.2 1 0 0 1 1 1 0 Putative mucin or carbohydrate-binding module AAA PF00004.29 KIK43188.1 - 1.3e-85 284.5 0.0 2e-41 141.5 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIK43188.1 - 1.2e-23 82.6 2.3 1.5e-11 43.9 0.1 3.3 3 0 0 3 3 3 2 AAA+ lid domain RuvB_N PF05496.12 KIK43188.1 - 7.7e-12 45.2 0.0 0.00038 20.2 0.0 3.4 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KIK43188.1 - 6.5e-11 42.4 0.0 9.6e-05 22.4 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIK43188.1 - 1.2e-10 42.0 1.5 0.00011 22.6 0.2 3.9 2 2 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 KIK43188.1 - 6.8e-09 36.0 0.0 0.00051 20.2 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_2 PF07724.14 KIK43188.1 - 1.1e-08 35.4 0.0 0.0047 17.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KIK43188.1 - 5.4e-08 33.2 0.4 0.0051 17.1 0.0 4.1 2 2 1 3 3 3 1 AAA domain AAA_14 PF13173.6 KIK43188.1 - 1.1e-05 25.5 0.0 0.039 14.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KIK43188.1 - 1.2e-05 24.8 0.0 0.052 12.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain IstB_IS21 PF01695.17 KIK43188.1 - 1.2e-05 25.1 0.0 0.0084 15.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 KIK43188.1 - 0.0002 21.3 0.0 0.73 9.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KIK43188.1 - 0.00031 21.1 0.0 0.56 10.6 0.0 2.7 2 1 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.12 KIK43188.1 - 0.00045 19.6 0.0 0.037 13.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 KIK43188.1 - 0.00058 20.4 0.0 0.011 16.2 0.0 2.6 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KIK43188.1 - 0.00064 19.7 0.1 0.053 13.4 0.0 3.4 3 1 0 3 3 3 1 NACHT domain Viral_helicase1 PF01443.18 KIK43188.1 - 0.00088 19.1 0.0 0.025 14.3 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 KIK43188.1 - 0.0014 18.0 0.2 1.6 8.1 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KIK43188.1 - 0.0023 17.8 0.0 0.53 10.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KIK43188.1 - 0.0075 16.2 0.0 0.095 12.6 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_28 PF13521.6 KIK43188.1 - 0.011 16.0 0.0 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KIK43188.1 - 0.02 14.5 2.6 25 4.4 0.1 3.8 2 2 2 4 4 4 0 AAA domain AAA_7 PF12775.7 KIK43188.1 - 0.03 13.9 0.0 5.6 6.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 KIK43188.1 - 0.04 13.7 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KIK43188.1 - 0.074 12.8 0.0 4.3 7.0 0.0 3.0 3 1 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 KIK43188.1 - 0.086 12.5 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 KIK43188.1 - 0.094 11.9 0.0 0.33 10.1 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.22 KIK43188.1 - 0.097 11.8 0.0 4.5 6.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain FLILHELTA PF10306.9 KIK43190.1 - 4.4e-11 43.0 0.0 7.5e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 KIK43190.1 - 0.0026 18.3 0.0 0.0042 17.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) RicinB_lectin_2 PF14200.6 KIK43193.1 - 3.8e-12 46.8 5.5 3.2e-08 34.2 0.7 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIK43193.1 - 0.0036 17.5 0.1 0.12 12.6 0.0 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain WD40 PF00400.32 KIK43195.1 - 1.3e-34 117.6 12.0 0.00012 22.8 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43195.1 - 1.2e-09 38.4 2.3 0.00086 19.6 0.0 4.8 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK43195.1 - 1.6e-08 34.7 0.1 0.00074 19.4 0.0 2.5 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK43195.1 - 1.2e-05 24.4 5.4 0.052 12.5 0.1 4.1 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PH_6 PF15406.6 KIK43195.1 - 0.0015 18.8 1.6 0.048 13.9 0.2 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain PQQ_2 PF13360.6 KIK43195.1 - 0.0032 17.1 1.5 0.0064 16.1 0.4 1.9 2 0 0 2 2 2 1 PQQ-like domain Nup160 PF11715.8 KIK43195.1 - 0.006 15.3 1.6 1 7.9 0.1 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KIK43195.1 - 0.0073 15.3 0.2 0.26 10.2 0.0 2.7 2 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Me-amine-dh_H PF06433.11 KIK43195.1 - 0.0081 15.1 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Methylamine dehydrogenase heavy chain (MADH) FB_lectin PF07367.11 KIK43197.1 - 1.3e-27 96.4 0.0 1.4e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Fungal fruit body lectin MIP PF00230.20 KIK43197.1 - 0.056 13.1 0.1 0.06 13.0 0.1 1.2 1 0 0 1 1 1 0 Major intrinsic protein Pkinase_fungal PF17667.1 KIK43198.1 - 2.9e-24 85.6 0.0 5.8e-11 41.8 1.6 3.0 1 1 1 2 2 2 2 Fungal protein kinase Ribosomal_L3 PF00297.22 KIK43199.1 - 1.9e-187 622.7 8.6 2.2e-187 622.5 8.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 DUF5345 PF17280.2 KIK43200.1 - 0.043 13.8 1.1 0.12 12.3 1.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5345) VESA1_N PF12785.7 KIK43204.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 MRC1 PF09444.10 KIK43205.1 - 2.5e-23 83.2 31.5 2.5e-23 83.2 31.5 5.4 4 1 1 5 5 5 1 MRC1-like domain Acyltransferase PF01553.21 KIK43207.1 - 4.3e-20 71.7 0.0 6.2e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Na_Ca_ex PF01699.24 KIK43208.1 - 7.9e-11 42.1 25.4 1.5e-06 28.2 8.6 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein THOC2_N PF16134.5 KIK43211.1 - 4e-139 465.1 0.0 7.2e-139 464.3 0.0 1.4 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KIK43211.1 - 4.7e-87 292.0 0.0 1.1e-86 290.7 0.0 1.7 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KIK43211.1 - 2e-31 107.9 0.2 5.3e-31 106.5 0.2 1.8 1 0 0 1 1 1 1 Transcription- and export-related complex subunit GTP_cyclohydroI PF01227.22 KIK43212.1 - 7.1e-75 250.4 1.2 9.2e-75 250.0 1.2 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KIK43212.1 - 0.00045 20.3 0.0 0.0013 18.8 0.0 1.7 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.6 KIK43212.1 - 0.044 13.7 0.9 0.083 12.8 0.1 1.9 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain ABC_tran PF00005.27 KIK43213.1 - 6.4e-19 68.8 0.0 1.7e-18 67.4 0.0 1.8 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIK43213.1 - 0.0061 16.0 0.0 0.89 8.9 0.0 2.2 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIK43213.1 - 0.015 15.2 0.9 0.032 14.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 KIK43213.1 - 0.16 10.6 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.7 KIK43214.1 - 2.5e-36 124.1 0.3 1.6e-15 57.5 0.1 4.0 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK43214.1 - 5.3e-29 100.2 3.4 7e-08 32.9 0.3 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) SPX PF03105.19 KIK43214.1 - 1.6e-27 97.5 9.8 2.3e-14 54.1 5.0 3.3 1 1 1 2 2 2 2 SPX domain Ank_5 PF13857.6 KIK43214.1 - 1.1e-20 73.4 9.7 8.7e-05 22.7 0.1 7.2 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK43214.1 - 1.3e-19 68.2 8.6 0.00029 21.0 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KIK43214.1 - 4.9e-17 61.5 8.8 0.0001 22.5 0.1 7.6 7 0 0 7 7 7 4 Ankyrin repeat GDPD PF03009.17 KIK43214.1 - 3.3e-14 53.2 0.0 8.5e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Pex2_Pex12 PF04757.14 KIK43217.1 - 1.6e-48 165.3 4.9 1.9e-48 165.1 4.9 1.0 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 KIK43217.1 - 5.7e-06 26.1 3.4 8.8e-06 25.5 3.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK43217.1 - 0.00056 19.7 5.5 0.00087 19.1 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK43217.1 - 0.004 17.5 4.6 0.0067 16.7 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KIK43217.1 - 0.053 13.5 6.3 0.092 12.8 6.3 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KIK43217.1 - 0.09 12.7 4.4 0.14 12.0 4.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK43217.1 - 0.11 12.7 4.3 0.17 12.0 4.3 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KIK43217.1 - 0.32 10.8 3.1 9 6.2 0.8 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KIK43217.1 - 0.4 10.6 5.1 3.5 7.6 0.2 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Haem_degrading PF03928.14 KIK43218.1 - 3.4e-12 46.4 0.1 8.3e-12 45.2 0.1 1.6 1 1 0 1 1 1 1 Haem-degrading SSB PF00436.25 KIK43219.1 - 7.3e-18 64.5 0.0 9.1e-18 64.2 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family HBS1_N PF08938.10 KIK43220.1 - 1e-11 45.0 0.9 2.3e-11 43.9 0.9 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU PF00009.27 KIK43221.1 - 1.2e-42 145.6 0.0 1.7e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KIK43221.1 - 2.4e-14 53.6 0.0 1.2e-13 51.3 0.0 2.1 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KIK43221.1 - 1.2e-06 28.6 0.0 0.0031 17.6 0.0 2.4 1 1 1 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KIK43221.1 - 0.0091 16.4 0.1 0.02 15.3 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 AMPK1_CBM PF16561.5 KIK43223.1 - 1.4e-15 57.3 0.0 2.6e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase MitMem_reg PF13012.6 KIK43225.1 - 0.0041 17.5 5.4 0.014 15.8 1.6 2.3 1 1 0 2 2 2 1 Maintenance of mitochondrial structure and function FliJ PF02050.16 KIK43225.1 - 0.01 16.1 6.7 0.01 16.1 6.7 1.8 1 1 1 2 2 2 1 Flagellar FliJ protein Met_synt_B12 PF02965.17 KIK43225.1 - 0.018 14.5 5.0 0.023 14.2 5.0 1.1 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain ALMT PF11744.8 KIK43225.1 - 0.026 13.3 7.9 0.031 13.1 7.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Amidase PF01425.21 KIK43225.1 - 0.043 12.8 1.5 0.051 12.5 1.5 1.1 1 0 0 1 1 1 0 Amidase DUF2407_C PF13373.6 KIK43225.1 - 0.075 13.2 3.4 0.098 12.8 3.1 1.4 1 1 0 1 1 1 0 DUF2407 C-terminal domain Ntox28 PF15605.6 KIK43225.1 - 0.53 10.5 10.0 0.13 12.5 2.1 2.2 2 0 0 2 2 2 0 Bacterial toxin 28 V_ATPase_I PF01496.19 KIK43225.1 - 1.1 7.1 6.6 1.3 6.9 6.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM76 PF16046.5 KIK43225.1 - 1.5 8.1 15.0 1.8 7.8 15.0 1.0 1 0 0 1 1 1 0 FAM76 protein DUF2070 PF09843.9 KIK43225.1 - 1.6 6.9 4.2 1.5 7.0 2.8 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) SOAR PF16533.5 KIK43225.1 - 5.1 7.1 13.2 8.4 6.4 8.7 2.5 1 1 1 2 2 2 0 STIM1 Orai1-activating region APG6_N PF17675.1 KIK43225.1 - 8.4 6.9 19.7 1.2e+02 3.2 19.7 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region MS_channel PF00924.18 KIK43226.1 - 2.8e-24 85.8 0.5 4.4e-24 85.2 0.5 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KIK43226.1 - 5.2e-05 22.5 0.1 5.2e-05 22.5 0.1 1.9 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KIK43226.1 - 6.9e-05 22.2 0.2 0.00014 21.2 0.2 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KIK43226.1 - 8.2e-05 22.2 0.1 0.00028 20.6 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KIK43226.1 - 0.014 15.8 0.1 0.048 14.1 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain pair PBP1_TM PF14812.6 KIK43226.1 - 0.052 13.9 2.9 0.14 12.5 0.3 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EF-hand_8 PF13833.6 KIK43226.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair p450 PF00067.22 KIK43229.1 - 1.8e-09 36.9 0.6 2.2e-09 36.6 0.6 1.1 1 0 0 1 1 1 1 Cytochrome P450 HTH_17 PF12728.7 KIK43232.1 - 0.052 13.7 0.2 0.71 10.1 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain CHAT PF12770.7 KIK43233.1 - 1e-37 130.1 0.0 1.3e-37 129.8 0.0 1.0 1 0 0 1 1 1 1 CHAT domain Surp PF01805.20 KIK43233.1 - 0.085 12.9 0.0 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 Surp module FA_hydroxylase PF04116.13 KIK43236.1 - 3.5e-23 82.4 19.9 3.5e-23 82.4 19.9 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily F-box-like PF12937.7 KIK43237.1 - 0.001 18.9 0.2 0.0054 16.6 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK43237.1 - 0.48 10.4 2.6 0.74 9.8 1.2 2.0 2 0 0 2 2 2 0 F-box domain Cys_Met_Meta_PP PF01053.20 KIK43240.1 - 6.5e-143 475.9 0.0 7.4e-143 475.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KIK43240.1 - 1.5e-09 37.6 0.1 2.4e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KIK43240.1 - 3.8e-09 36.0 1.0 5.9e-09 35.4 0.1 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KIK43240.1 - 9.1e-08 31.6 0.0 1.4e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Asparaginase_C PF17763.1 KIK43240.1 - 0.0021 18.3 0.0 0.0063 16.7 0.0 1.8 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Beta_elim_lyase PF01212.21 KIK43240.1 - 0.0025 17.1 0.1 0.01 15.2 0.1 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KIK43240.1 - 0.0069 15.0 0.0 0.01 14.4 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase SepSecS PF05889.13 KIK43240.1 - 0.035 12.8 0.0 0.052 12.2 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS MMR_HSR1 PF01926.23 KIK43244.1 - 5.1e-06 26.5 0.0 9.1e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK43244.1 - 1.9e-05 24.1 0.0 2.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIK43244.1 - 9e-05 22.6 1.4 0.0012 18.9 0.6 2.3 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KIK43244.1 - 0.0001 22.2 0.1 0.0002 21.3 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase Roc PF08477.13 KIK43244.1 - 0.00039 20.6 0.0 0.0053 17.0 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 KIK43244.1 - 0.0043 16.2 0.0 0.0097 15.0 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 KIK43244.1 - 0.0048 17.4 0.2 0.008 16.7 0.2 1.7 1 1 0 1 1 1 1 ABC transporter Septin PF00735.18 KIK43244.1 - 0.0056 16.0 0.0 0.009 15.3 0.0 1.2 1 0 0 1 1 1 1 Septin AAA_16 PF13191.6 KIK43244.1 - 0.0075 16.7 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Ras PF00071.22 KIK43244.1 - 0.025 14.2 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 Ras family AAA_23 PF13476.6 KIK43244.1 - 0.24 11.9 0.4 0.5 10.9 0.2 1.5 2 0 0 2 2 2 0 AAA domain Na_Pi_cotrans PF02690.15 KIK43246.1 - 0.084 13.0 5.6 0.57 10.3 0.5 2.3 2 0 0 2 2 2 0 Na+/Pi-cotransporter Macoilin PF09726.9 KIK43246.1 - 0.3 9.6 9.4 0.42 9.1 9.4 1.1 1 0 0 1 1 1 0 Macoilin family GATase PF00117.28 KIK43247.1 - 3.5e-09 36.7 0.0 1.4e-05 25.0 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferase class-I CPSase_L_D2 PF02786.17 KIK43247.1 - 2e-07 30.7 0.0 3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.6 KIK43247.1 - 0.0028 17.4 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon MMR_HSR1 PF01926.23 KIK43250.1 - 6.2e-12 45.6 0.0 1.4e-11 44.5 0.0 1.6 2 0 0 2 2 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK43250.1 - 2e-06 27.3 0.0 3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 KIK43250.1 - 2.5e-05 24.5 0.5 0.00015 22.0 0.0 2.4 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KIK43250.1 - 2.8e-05 24.1 0.1 0.00023 21.1 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase Ras PF00071.22 KIK43250.1 - 4.2e-05 23.2 0.1 0.00013 21.6 0.0 1.8 2 0 0 2 2 2 1 Ras family Dynamin_N PF00350.23 KIK43250.1 - 0.00012 22.2 0.2 0.0016 18.6 0.4 2.2 1 1 1 2 2 2 1 Dynamin family ABC_tran PF00005.27 KIK43250.1 - 0.00058 20.4 0.0 0.0013 19.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KIK43250.1 - 0.00069 19.3 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KIK43250.1 - 0.00082 19.8 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 KIK43250.1 - 0.0038 17.8 0.0 0.0065 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KIK43250.1 - 0.0045 16.5 0.2 0.0091 15.5 0.0 1.5 2 0 0 2 2 1 1 P-loop containing dynein motor region DUF815 PF05673.13 KIK43250.1 - 0.005 16.0 0.1 0.0097 15.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KIK43250.1 - 0.0073 16.6 0.0 0.02 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KIK43250.1 - 0.0076 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein SMC_N PF02463.19 KIK43250.1 - 0.032 13.7 0.4 0.068 12.6 0.1 1.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 KIK43250.1 - 0.037 13.4 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family IIGP PF05049.13 KIK43250.1 - 0.038 13.0 0.1 0.062 12.4 0.1 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Septin PF00735.18 KIK43250.1 - 0.038 13.2 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Septin FeoB_N PF02421.18 KIK43250.1 - 0.04 13.4 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B RNA_helicase PF00910.22 KIK43250.1 - 0.059 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KIK43250.1 - 0.069 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 KIK43250.1 - 0.088 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain SRPRB PF09439.10 KIK43250.1 - 0.088 12.2 0.1 0.29 10.5 0.1 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_13 PF13166.6 KIK43250.1 - 0.32 9.6 2.2 0.21 10.2 0.5 1.4 2 0 0 2 2 2 0 AAA domain Caskin-Pro-rich PF16907.5 KIK43250.1 - 3.7 8.1 7.4 11 6.6 7.4 1.9 1 1 0 1 1 1 0 Proline rich region of Caskin proteins Questin_oxidase PF14027.6 KIK43251.1 - 4.4e-88 296.1 0.8 5.4e-88 295.8 0.8 1.1 1 0 0 1 1 1 1 Questin oxidase-like Questin_oxidase PF14027.6 KIK43252.1 - 1.5e-88 297.6 0.0 1.9e-88 297.3 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like Pkinase PF00069.25 KIK43253.1 - 1.6e-41 142.5 0.0 2.5e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK43253.1 - 5e-38 130.9 0.0 8.1e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4238 PF14022.6 KIK43253.1 - 4e-06 26.6 0.0 2.2e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4238) APH PF01636.23 KIK43253.1 - 0.0016 18.4 0.1 0.0064 16.4 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family SNARE_assoc PF09335.11 KIK43254.1 - 2.5e-17 63.4 7.4 2.5e-17 63.4 7.4 1.5 2 0 0 2 2 2 1 SNARE associated Golgi protein MMR_HSR1 PF01926.23 KIK43255.1 - 8.2e-11 42.0 0.0 1e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KIK43255.1 - 1.8e-06 28.1 0.1 0.0018 18.4 0.1 2.2 2 0 0 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 KIK43255.1 - 4.2e-06 26.8 0.0 1.1e-05 25.5 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KIK43255.1 - 1.4e-05 24.6 0.0 1.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 KIK43255.1 - 1.4e-05 25.3 0.0 7.4e-05 23.0 0.0 2.0 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KIK43255.1 - 0.0002 21.9 0.0 0.00029 21.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Ras PF00071.22 KIK43255.1 - 0.00055 19.6 0.0 0.0055 16.3 0.0 2.0 2 0 0 2 2 2 1 Ras family IIGP PF05049.13 KIK43255.1 - 0.00067 18.8 0.0 0.0011 18.1 0.0 1.4 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 KIK43255.1 - 0.00099 19.6 0.1 0.0014 19.1 0.1 1.3 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KIK43255.1 - 0.0026 17.4 0.1 0.056 13.2 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain FeoB_N PF02421.18 KIK43255.1 - 0.0032 17.0 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_23 PF13476.6 KIK43255.1 - 0.005 17.4 0.5 0.05 14.1 0.5 1.9 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KIK43255.1 - 0.0054 16.9 0.0 0.0095 16.0 0.0 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 KIK43255.1 - 0.0069 16.7 0.0 0.01 16.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 KIK43255.1 - 0.016 14.6 0.0 0.018 14.4 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 KIK43255.1 - 0.032 13.6 0.2 0.052 12.9 0.2 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family SRPRB PF09439.10 KIK43255.1 - 0.048 13.1 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RNA_helicase PF00910.22 KIK43255.1 - 0.049 14.0 0.0 0.074 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.13 KIK43255.1 - 0.055 12.6 0.0 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 KIK43255.1 - 0.063 13.7 0.0 0.081 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain NLE PF08154.12 KIK43255.1 - 0.064 13.8 0.0 0.7 10.5 0.0 2.2 2 0 0 2 2 2 0 NLE (NUC135) domain T2SSE PF00437.20 KIK43255.1 - 0.074 12.1 0.1 0.2 10.7 0.1 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 KIK43255.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 KIK43255.1 - 0.15 11.5 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 KIK43255.1 - 0.18 11.4 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SNARE_assoc PF09335.11 KIK43257.1 - 3.4e-16 59.8 9.2 3.4e-16 59.8 9.2 2.2 3 0 0 3 3 3 1 SNARE associated Golgi protein Wzy_C_2 PF11846.8 KIK43257.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal GNVR PF13807.6 KIK43257.1 - 0.29 11.1 1.5 5.8 6.9 0.0 2.5 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase Trp_halogenase PF04820.14 KIK43258.1 - 2e-26 92.9 1.0 5.3e-14 51.9 0.0 2.6 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KIK43258.1 - 2.3e-10 40.3 0.0 5.4e-10 39.0 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIK43258.1 - 1.3e-07 31.7 0.1 4.2e-07 30.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIK43258.1 - 3.5e-06 26.4 0.0 0.00047 19.4 0.1 2.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KIK43258.1 - 4.4e-06 26.5 0.2 0.00024 20.8 0.1 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK43258.1 - 1.2e-05 24.8 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIK43258.1 - 1.3e-05 24.8 0.1 8.1e-05 22.1 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KIK43258.1 - 6.1e-05 22.3 0.1 9.8e-05 21.6 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KIK43258.1 - 6.7e-05 21.8 0.1 0.00011 21.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KIK43258.1 - 0.0034 17.9 0.2 0.0099 16.4 0.0 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK43258.1 - 0.029 13.6 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KIK43258.1 - 0.036 13.1 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 KIK43258.1 - 0.08 12.6 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KIK43258.1 - 0.093 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KIK43258.1 - 0.2 11.5 0.0 0.47 10.3 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AMP-binding PF00501.28 KIK43259.1 - 3.4e-64 217.0 0.0 4.8e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 KIK43259.1 - 8.7e-29 101.3 0.1 2.4e-27 96.6 0.1 2.3 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 KIK43259.1 - 2e-08 34.5 0.1 1.7e-07 31.5 0.0 2.7 3 0 0 3 3 3 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 KIK43259.1 - 0.00019 22.1 0.2 0.00042 21.0 0.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.11 KIK43259.1 - 0.0072 15.9 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.20 KIK43259.1 - 0.043 13.5 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK43259.1 - 0.062 12.5 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PhyH PF05721.13 KIK43261.1 - 1.4e-10 41.8 0.0 1.9e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF4232 PF14016.6 KIK43261.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) Get5_bdg PF16843.5 KIK43262.1 - 0.0052 16.2 0.1 7.5 6.1 0.1 3.2 3 0 0 3 3 3 3 Binding domain to Get4 on Get5, Golgi to ER traffic protein zf-H2C2_5 PF13909.6 KIK43263.1 - 4.4e-10 39.1 12.0 0.0003 20.5 0.7 3.5 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KIK43263.1 - 4.8e-07 29.9 14.3 3.2e-05 24.2 0.7 3.3 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KIK43263.1 - 5.8e-06 26.5 20.8 0.0021 18.4 2.5 3.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK43263.1 - 0.0023 18.6 16.8 0.13 13.2 1.8 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger IBR PF01485.21 KIK43263.1 - 0.063 13.5 6.0 0.19 12.0 6.0 1.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Glyco_hydro_42M PF08532.10 KIK43263.1 - 0.12 11.9 0.1 0.31 10.5 0.1 1.6 2 0 0 2 2 2 0 Beta-galactosidase trimerisation domain zf_C2H2_ZHX PF18387.1 KIK43263.1 - 0.12 12.0 1.5 1.6 8.4 0.1 2.3 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_7 PF15269.6 KIK43263.1 - 1.2 9.3 6.0 0.18 11.9 0.9 2.4 1 1 2 3 3 3 0 Zinc-finger WD40 PF00400.32 KIK43264.1 - 1.6e-05 25.6 1.2 0.0024 18.7 0.1 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43264.1 - 0.1 12.9 0.0 10 6.5 0.0 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF2637 PF10935.8 KIK43266.1 - 0.85 9.5 5.1 0.22 11.4 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2637) PHO4 PF01384.20 KIK43266.1 - 6 5.8 16.9 1.5e+04 -5.3 16.8 2.9 1 1 0 1 1 1 0 Phosphate transporter family Med25_VWA PF11265.8 KIK43269.1 - 0.074 12.9 0.1 0.099 12.4 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A PAP2_3 PF14378.6 KIK43271.1 - 8.7e-25 87.5 15.0 8.7e-25 87.5 15.0 2.1 1 1 1 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KIK43271.1 - 8.5e-11 41.8 4.9 8.5e-11 41.8 4.9 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KIK43271.1 - 0.023 15.2 5.3 0.023 15.2 5.3 2.3 3 0 0 3 3 3 0 PAP2 superfamily C-terminal Methyltransf_23 PF13489.6 KIK43275.1 - 6.6e-10 39.1 0.0 8.4e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK43275.1 - 2.3e-06 28.2 0.0 3.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK43275.1 - 5.4e-06 27.0 0.0 9.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK43275.1 - 0.00021 22.0 0.0 0.00035 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK43275.1 - 0.0062 16.3 0.0 0.45 10.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 KIK43275.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Pkinase_fungal PF17667.1 KIK43276.1 - 2.2e-14 53.0 0.1 2.5e-14 52.9 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase Zip PF02535.22 KIK43278.1 - 1.3e-51 175.8 11.8 1e-50 172.9 11.8 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Tmemb_55A PF09788.9 KIK43279.1 - 0.017 14.2 0.5 0.017 14.2 0.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A CHAT PF12770.7 KIK43280.1 - 9.1e-32 110.6 0.0 1.8e-31 109.6 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK43280.1 - 2.6e-09 36.6 4.0 0.41 10.6 0.0 8.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK43280.1 - 0.0004 20.6 15.9 1 9.7 0.1 8.7 8 2 2 10 10 10 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK43280.1 - 0.0024 17.6 2.9 11 6.0 0.0 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF2730 PF10805.8 KIK43280.1 - 0.017 15.2 0.0 9.8 6.3 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) TPR_11 PF13414.6 KIK43280.1 - 0.084 12.6 2.4 4.9 6.9 0.0 4.8 6 0 0 6 6 6 0 TPR repeat TPR_8 PF13181.6 KIK43280.1 - 0.089 13.1 4.5 32 5.1 0.0 6.2 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK43280.1 - 7.1 7.0 8.9 13 6.2 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat AA_permease_2 PF13520.6 KIK43281.1 - 6.9e-65 219.5 37.2 9.4e-65 219.1 37.2 1.2 1 0 0 1 1 1 1 Amino acid permease UNC-93 PF05978.16 KIK43281.1 - 0.037 13.7 0.2 0.037 13.7 0.2 2.4 2 1 0 2 2 2 0 Ion channel regulatory protein UNC-93 DUF423 PF04241.15 KIK43281.1 - 9.7 6.5 7.9 5.6 7.2 1.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF423) Peptidase_M48 PF01435.18 KIK43283.1 - 4.7e-17 62.4 0.0 8.6e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.9 KIK43283.1 - 0.27 10.8 0.4 0.47 10.0 0.4 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) p450 PF00067.22 KIK43285.1 - 5.5e-60 203.4 0.0 6.7e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Svf1_C PF17187.4 KIK43286.1 - 1.9e-47 161.1 0.0 2.9e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KIK43286.1 - 7.7e-47 159.4 0.0 1e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain DUF4646 PF15496.6 KIK43289.1 - 3.9e-41 140.6 0.0 6e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) SR-25 PF10500.9 KIK43289.1 - 8e-05 22.4 18.8 0.00015 21.5 18.8 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein MRP-S26 PF14943.6 KIK43289.1 - 0.043 13.7 5.3 0.068 13.1 5.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF4407 PF14362.6 KIK43289.1 - 0.24 10.7 1.5 0.32 10.3 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) rRNA_processing PF08524.11 KIK43289.1 - 1.8 8.6 13.8 3.2 7.8 13.8 1.3 1 0 0 1 1 1 0 rRNA processing IMUP PF15761.5 KIK43289.1 - 2 9.1 19.7 5.7 7.7 19.7 1.8 1 1 0 1 1 1 0 Immortalisation up-regulated protein DUF2828 PF11443.8 KIK43289.1 - 3.5 5.6 6.1 61 1.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Peptidase_S49_N PF08496.10 KIK43289.1 - 8.2 6.5 6.1 14 5.7 6.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Med18 PF09637.10 KIK43290.1 - 0.029 14.2 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Med18 protein DUF4756 PF15948.5 KIK43290.1 - 0.051 13.4 0.8 0.075 12.9 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4756) Phage_holin_Dp1 PF16938.5 KIK43291.1 - 0.015 15.5 4.2 1.5 9.1 0.4 3.0 2 1 0 2 2 2 0 Putative phage holin Dp-1 DUF2070 PF09843.9 KIK43291.1 - 8.7 4.5 11.3 11 4.2 11.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Actin PF00022.19 KIK43293.1 - 6.7e-40 136.9 0.0 2e-34 118.9 0.0 2.5 2 1 0 2 2 2 2 Actin PB1 PF00564.24 KIK43295.1 - 0.19 11.7 0.1 6.7 6.7 0.0 2.5 2 0 0 2 2 2 0 PB1 domain Aldo_ket_red PF00248.21 KIK43298.1 - 3.6e-70 236.5 0.2 4e-70 236.3 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PfkB PF00294.24 KIK43300.1 - 0.00037 19.9 0.0 0.037 13.3 0.0 2.7 3 0 0 3 3 3 2 pfkB family carbohydrate kinase TPR_19 PF14559.6 KIK43302.1 - 8.3e-11 42.2 8.9 0.00011 22.6 1.4 4.8 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIK43302.1 - 2.1e-10 41.1 1.4 0.00086 19.9 0.0 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK43302.1 - 4e-08 33.4 7.5 0.029 15.2 0.1 5.3 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK43302.1 - 3.2e-05 23.7 9.7 1.5 9.1 0.0 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK43302.1 - 4e-05 23.2 1.5 0.97 9.2 0.0 4.7 4 1 1 5 5 5 1 TPR repeat TPR_7 PF13176.6 KIK43302.1 - 0.00047 20.0 0.6 6.8 7.0 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 KIK43302.1 - 0.00063 20.0 6.1 0.06 13.7 0.5 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK43302.1 - 0.00065 19.4 2.7 43 4.2 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK43302.1 - 0.0008 19.6 6.3 2.1 8.7 2.5 4.4 2 2 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KIK43302.1 - 0.00097 19.4 2.4 17 5.8 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIK43302.1 - 0.021 15.2 2.3 0.27 11.7 0.2 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KIK43302.1 - 0.047 13.8 11.2 0.98 9.6 0.1 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KIK43302.1 - 0.078 12.6 0.3 8.9 6.0 0.0 3.0 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Pex26 PF07163.12 KIK43302.1 - 0.11 11.7 0.8 0.35 10.1 0.6 1.9 1 1 1 2 2 2 0 Pex26 protein TPR_6 PF13174.6 KIK43302.1 - 0.13 12.9 1.5 66 4.5 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIK43302.1 - 0.17 11.8 1.8 13 5.8 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIK43302.1 - 0.92 10.3 8.4 1.3 9.8 0.0 3.7 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK43302.1 - 1 8.6 4.7 36 3.6 0.2 3.2 2 2 1 3 3 3 0 MalT-like TPR region TPR_21 PF09976.9 KIK43302.1 - 9.5 5.9 9.2 36 4.0 0.1 3.8 3 2 1 4 4 4 0 Tetratricopeptide repeat-like domain zf-HIT PF04438.16 KIK43305.1 - 0.022 14.6 0.3 0.049 13.5 0.3 1.6 1 0 0 1 1 1 0 HIT zinc finger TPR_2 PF07719.17 KIK43307.1 - 0.00013 21.8 8.4 0.02 15.0 0.2 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK43307.1 - 0.00015 21.5 1.8 0.36 10.7 0.4 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK43307.1 - 0.0023 17.6 1.6 0.012 15.3 0.1 2.9 4 0 0 4 4 4 1 TPR repeat LprI PF07007.12 KIK43307.1 - 0.16 12.6 5.0 6.6 7.4 0.1 2.8 2 0 0 2 2 2 0 Lysozyme inhibitor LprI Aminotran_1_2 PF00155.21 KIK43308.1 - 8e-13 48.3 0.0 2.1e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Zn_clus PF00172.18 KIK43310.1 - 6.9e-10 38.9 14.0 1.2e-09 38.2 14.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2318 PF10080.9 KIK43310.1 - 0.047 13.8 0.9 0.075 13.2 0.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Ctf8 PF09696.10 KIK43312.1 - 7.4e-17 62.0 0.1 3.9e-15 56.4 0.1 2.0 1 1 0 1 1 1 1 Ctf8 TSNR_N PF04705.12 KIK43317.1 - 0.093 12.8 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Thiostrepton-resistance methylase, N terminus Pkinase_fungal PF17667.1 KIK43317.1 - 0.15 10.8 0.0 0.15 10.8 0.0 1.0 1 0 0 1 1 1 0 Fungal protein kinase F-box-like PF12937.7 KIK43319.1 - 1.3e-08 34.5 0.1 3.7e-08 33.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIK43319.1 - 0.027 14.9 0.1 42 4.8 0.1 4.9 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) PNP_UDP_1 PF01048.20 KIK43320.1 - 7.6e-24 84.2 0.0 1.1e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily HMG_box PF00505.19 KIK43322.1 - 3.1e-11 43.5 0.8 7.2e-10 39.2 0.1 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK43322.1 - 2.7e-09 37.5 0.1 4.5e-07 30.4 0.0 2.7 2 0 0 2 2 2 2 HMG-box domain Fasciclin PF02469.22 KIK43324.1 - 6.7e-34 116.9 0.3 3.5e-20 72.5 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain Pkinase PF00069.25 KIK43325.1 - 1.6e-68 231.0 0.0 2.3e-66 223.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK43325.1 - 2.7e-35 121.9 0.0 6.5e-32 110.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK43325.1 - 4.6e-06 25.7 1.2 6.4e-06 25.2 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KIK43325.1 - 6.5e-05 22.4 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK43325.1 - 0.016 14.6 0.1 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KIK43325.1 - 0.024 14.1 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 KIK43325.1 - 0.13 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4131 PF13567.6 KIK43327.1 - 0.76 9.4 3.8 1.3 8.6 3.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) FMO-like PF00743.19 KIK43331.1 - 3.5e-11 42.2 0.0 2.2e-06 26.4 0.0 2.2 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK43331.1 - 6.7e-08 32.1 0.0 2.5e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK43331.1 - 0.0025 17.1 0.0 0.033 13.4 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK43331.1 - 0.14 11.3 0.1 0.68 9.0 0.0 1.9 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Glyco_transf_90 PF05686.12 KIK43332.1 - 3.8e-22 78.8 0.2 3.8e-20 72.2 0.5 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 F-box-like PF12937.7 KIK43336.1 - 0.047 13.6 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 F-box-like AA_permease_2 PF13520.6 KIK43337.1 - 3.5e-63 213.9 53.8 4.2e-63 213.7 53.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK43337.1 - 3.9e-14 52.1 50.6 8.1e-14 51.1 50.6 1.4 1 1 0 1 1 1 1 Amino acid permease Epiglycanin_C PF14654.6 KIK43337.1 - 0.09 12.8 2.5 0.13 12.3 0.8 2.2 1 1 1 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region HTH_23 PF13384.6 KIK43338.1 - 4.3e-07 29.5 0.1 1.6e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KIK43338.1 - 2.7e-06 27.4 0.0 1.3e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_33 PF13592.6 KIK43338.1 - 4.4e-06 26.2 0.0 9.6e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.6 KIK43338.1 - 0.00032 21.2 0.1 0.0012 19.4 0.0 2.0 3 0 0 3 3 3 1 Homeodomain-like domain Terminase_5 PF06056.12 KIK43338.1 - 0.0027 17.6 0.0 0.0044 16.9 0.0 1.3 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_1 PF01527.20 KIK43338.1 - 0.085 13.2 0.0 0.2 12.0 0.0 1.6 2 0 0 2 2 2 0 Transposase Arg_repressor PF01316.21 KIK43338.1 - 0.16 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Tnp_zf-ribbon_2 PF13842.6 KIK43339.1 - 0.14 13.0 1.2 0.3 11.9 0.1 2.0 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Putative_PNPOx PF01243.20 KIK43344.1 - 0.00017 21.7 0.0 0.0004 20.5 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF1538 PF07556.11 KIK43344.1 - 0.015 14.6 0.0 0.02 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1538) Sugarporin_N PF11471.8 KIK43345.1 - 0.11 12.5 0.2 0.13 12.2 0.2 1.2 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension CHAT PF12770.7 KIK43349.1 - 4.3e-30 105.1 0.0 1.3e-29 103.6 0.0 1.8 2 0 0 2 2 2 1 CHAT domain TPR_12 PF13424.6 KIK43349.1 - 1.6e-12 47.5 15.6 0.086 13.1 0.0 7.0 5 3 2 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 KIK43349.1 - 8.6e-10 37.9 3.9 1.3 9.2 0.0 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_10 PF13374.6 KIK43349.1 - 1.4e-09 37.5 19.4 0.035 14.0 0.0 9.0 8 2 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 KIK43349.1 - 0.01 16.6 15.6 24 6.1 0.0 8.3 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK43349.1 - 0.012 15.4 1.8 11 6.0 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK43349.1 - 0.19 12.4 7.0 3.6 8.3 0.1 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK43349.1 - 0.3 10.8 3.2 5 6.9 0.0 4.1 6 0 0 6 6 6 0 TPR repeat Acetyltransf_6 PF13480.7 KIK43349.1 - 2 8.5 4.9 4.5 7.4 0.1 3.7 4 1 1 5 5 5 0 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.7 KIK43350.1 - 3.7e-07 31.0 0.3 4.5e-07 30.7 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK43350.1 - 2.4e-05 23.7 0.1 0.11 11.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK43350.1 - 0.00032 20.4 0.1 0.00051 19.8 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KIK43350.1 - 0.039 13.7 0.1 0.83 9.3 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein DUF915 PF06028.11 KIK43350.1 - 0.084 12.2 0.1 11 5.2 0.0 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) RT_RNaseH_2 PF17919.1 KIK43351.1 - 9.4e-08 32.0 0.0 1.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 KIK43352.1 - 2.9e-05 24.6 0.0 7.3e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK43352.1 - 0.0022 18.5 0.0 0.0059 17.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KIK43352.1 - 0.044 13.5 0.1 0.085 12.6 0.1 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Abhydrolase_6 PF12697.7 KIK43353.1 - 0.0082 16.8 0.4 0.01 16.5 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family CHAT PF12770.7 KIK43354.1 - 8.5e-37 127.1 0.3 9.3e-37 127.0 0.3 1.0 1 0 0 1 1 1 1 CHAT domain Peptidase_C25 PF01364.18 KIK43354.1 - 0.15 11.2 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C25 TPR_10 PF13374.6 KIK43355.1 - 1e-50 168.3 23.1 4.3e-06 26.4 0.0 17.0 17 0 0 17 17 17 12 Tetratricopeptide repeat TPR_12 PF13424.6 KIK43355.1 - 1.7e-35 121.2 12.1 0.019 15.2 0.0 15.9 10 5 5 16 16 14 7 Tetratricopeptide repeat TPR_14 PF13428.6 KIK43355.1 - 1.3e-14 53.6 20.4 1.9 9.5 0.0 13.4 13 1 1 14 14 13 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK43355.1 - 1.9e-14 52.5 11.1 6.9 6.9 0.0 12.7 13 1 1 14 14 11 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK43355.1 - 8.8e-14 50.9 7.2 0.027 14.1 0.1 11.7 13 0 0 13 13 12 3 TPR repeat TPR_8 PF13181.6 KIK43355.1 - 1.6e-11 43.4 4.3 1.5 9.2 0.0 10.4 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK43355.1 - 1.6e-10 40.6 3.6 27 5.5 0.0 11.9 14 0 0 14 14 13 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK43355.1 - 7.3e-10 38.2 40.9 0.22 11.4 0.2 15.0 18 0 0 18 18 17 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIK43355.1 - 1e-08 34.6 23.8 0.36 11.1 0.1 11.1 12 0 0 12 12 12 4 Tetratricopeptide repeat MIT PF04212.18 KIK43355.1 - 4.3e-06 26.7 3.0 2.7 8.1 0.0 8.3 12 0 0 12 12 12 1 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 KIK43355.1 - 6.7e-06 26.6 20.3 6 7.6 0.3 10.8 10 3 3 13 13 12 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK43355.1 - 7.7e-06 26.3 16.3 19 5.9 0.0 11.7 15 0 0 15 15 13 0 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 KIK43355.1 - 0.00012 22.0 15.4 8 6.6 0.0 9.6 11 0 0 11 11 10 1 Exonuclease VII small subunit TPR_6 PF13174.6 KIK43355.1 - 0.0018 18.8 7.2 11 6.9 0.1 8.0 9 0 0 9 9 8 1 Tetratricopeptide repeat T3SS_ATPase_C PF18269.1 KIK43355.1 - 0.0022 17.8 14.1 19 5.2 0.0 10.2 13 0 0 13 13 13 0 T3SS EscN ATPase C-terminal domain CO_dh PF02552.16 KIK43355.1 - 0.22 11.3 0.0 2e+02 1.7 0.0 4.7 6 0 0 6 6 6 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit WD40 PF00400.32 KIK43357.1 - 1.1e-05 26.1 1.3 0.0022 18.8 1.3 3.0 1 1 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43357.1 - 0.055 13.8 0.0 8.5 6.8 0.0 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK43357.1 - 0.099 12.6 0.3 3.8 7.6 0.0 2.6 2 1 0 2 2 2 0 WD40-like Beta Propeller Repeat Abhydrolase_3 PF07859.13 KIK43360.1 - 1.3e-20 74.2 0.5 3.8e-11 43.2 0.0 3.7 3 1 0 3 3 3 3 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK43360.1 - 1.9e-08 33.6 0.0 6.6e-07 28.5 0.0 2.7 3 0 0 3 3 3 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 KIK43360.1 - 0.026 14.3 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase COesterase PF00135.28 KIK43360.1 - 0.083 11.7 0.2 0.23 10.3 0.1 1.7 2 0 0 2 2 2 0 Carboxylesterase family MxiM PF11441.8 KIK43360.1 - 0.21 11.9 0.0 0.45 10.8 0.0 1.5 1 0 0 1 1 1 0 Pilot protein MxiM Lactamase_B_6 PF16661.5 KIK43361.1 - 2.6e-49 167.3 0.0 1.3e-48 165.0 0.0 2.2 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KIK43361.1 - 3.6e-23 82.6 15.9 1.9e-19 70.5 0.0 4.3 4 1 1 5 5 5 2 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KIK43361.1 - 1.6e-17 63.8 0.0 8.2e-17 61.5 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 KIK43361.1 - 4.1e-05 23.4 0.0 0.00028 20.7 0.0 2.3 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain tRNA-synt_1c PF00749.21 KIK43362.1 - 1.3e-107 359.3 0.0 1.7e-107 359.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 KIK43362.1 - 2.2e-40 138.3 0.2 3.5e-40 137.7 0.2 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 KIK43362.1 - 1.9e-30 106.0 0.0 3.6e-30 105.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 KIK43362.1 - 9.2e-08 32.9 0.4 2.3e-07 31.6 0.4 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 PAF-AH_p_II PF03403.13 KIK43363.1 - 2.9e-37 128.1 0.0 4.2e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 KIK43363.1 - 1.4e-06 27.8 0.0 0.014 14.7 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KIK43363.1 - 1.7e-05 23.9 0.0 0.002 17.1 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 KIK43363.1 - 0.00024 21.8 2.3 0.00042 21.0 1.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KIK43363.1 - 0.0057 15.7 0.0 0.11 11.5 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase DLH PF01738.18 KIK43363.1 - 0.058 12.9 0.0 0.57 9.7 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Thioesterase PF00975.20 KIK43363.1 - 0.06 13.4 0.0 11 6.1 0.0 2.4 2 0 0 2 2 2 0 Thioesterase domain DUF202 PF02656.15 KIK43364.1 - 3.3e-15 56.3 2.7 3.3e-15 56.3 2.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SANT_DAMP1_like PF16282.5 KIK43365.1 - 3.4e-31 107.3 5.4 5.4e-31 106.6 5.4 1.3 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 KIK43365.1 - 0.00011 22.3 0.5 0.00032 20.8 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK43365.1 - 0.0003 21.0 0.1 0.00081 19.6 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DMAP1 PF05499.12 KIK43365.1 - 0.44 10.4 4.4 3.9 7.3 4.4 2.1 1 1 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) zf-U1 PF06220.12 KIK43366.1 - 1.6e-20 72.6 4.1 2.1e-20 72.2 4.1 1.2 1 0 0 1 1 1 1 U1 zinc finger CLIP1_ZNF PF16641.5 KIK43366.1 - 0.083 12.8 1.5 0.17 11.8 1.5 1.6 1 0 0 1 1 1 0 CLIP1 zinc knuckle LSM PF01423.22 KIK43367.1 - 1.5e-19 69.5 0.2 1.7e-19 69.3 0.2 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 KIK43367.1 - 0.063 13.4 0.1 0.34 11.1 0.0 1.9 1 1 1 2 2 2 0 RimP C-terminal SH3 domain DUF4050 PF13259.6 KIK43368.1 - 0.048 14.0 0.2 2.2 8.6 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4050) LRR_4 PF12799.7 KIK43369.1 - 1e-12 48.0 7.8 0.48 10.9 0.1 7.9 6 3 2 8 8 8 5 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KIK43369.1 - 3.2e-09 36.5 2.6 3.2e-09 36.5 2.6 2.4 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.6 KIK43369.1 - 4.5e-05 23.2 19.5 7 7.0 0.1 9.3 10 0 0 10 10 10 3 Leucine Rich repeat F-box PF00646.33 KIK43369.1 - 0.0012 18.6 7.6 0.0019 18.0 2.2 3.2 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.6 KIK43369.1 - 1.1 9.1 10.2 45 3.9 0.1 5.4 5 1 0 5 5 5 0 Leucine rich repeat Acetyltransf_1 PF00583.25 KIK43370.1 - 2e-12 47.4 0.0 2.3e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK43370.1 - 4e-08 33.3 0.0 5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK43370.1 - 8.1e-06 26.2 0.0 1.1e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK43370.1 - 0.00017 21.5 0.1 0.00029 20.7 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KIK43370.1 - 0.0019 18.3 0.2 0.0035 17.4 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KIK43370.1 - 0.0059 16.1 0.7 0.0091 15.5 0.1 1.6 2 0 0 2 2 2 1 Putative acetyl-transferase DUF676 PF05057.14 KIK43371.1 - 6.2e-06 25.9 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 KIK43371.1 - 0.00014 21.8 0.0 0.00026 20.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIK43371.1 - 0.00028 21.5 6.7 0.00054 20.6 6.7 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KIK43371.1 - 0.00075 19.3 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 KIK43371.1 - 0.0025 17.7 0.1 0.0039 17.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK43371.1 - 0.0028 16.9 0.0 0.0074 15.6 0.0 1.7 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF900 PF05990.12 KIK43371.1 - 0.0055 16.2 0.0 0.026 14.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF2974 PF11187.8 KIK43371.1 - 0.013 15.0 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) LCAT PF02450.15 KIK43371.1 - 0.05 12.8 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 KIK43371.1 - 0.072 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF915 PF06028.11 KIK43371.1 - 0.11 11.8 0.0 9.7 5.4 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF629 PF04780.12 KIK43372.1 - 0.064 11.8 0.5 0.11 11.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2 PF00096.26 KIK43372.1 - 0.16 12.5 1.9 0.44 11.1 1.9 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF2052 PF09747.9 KIK43373.1 - 5.1e-06 26.8 20.1 1e-05 25.7 20.1 1.6 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Myb_DNA-binding PF00249.31 KIK43375.1 - 5.7e-21 74.4 8.6 1.7e-10 40.9 0.0 4.8 5 1 0 5 5 5 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK43375.1 - 1.8e-15 57.0 13.4 3e-08 33.8 0.1 4.6 5 0 0 5 5 5 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KIK43375.1 - 0.0015 18.6 0.0 2 8.6 0.1 2.5 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 KIK43375.1 - 0.0072 16.7 9.2 0.011 16.1 3.0 3.7 2 2 0 3 3 3 1 Myb/SANT-like DNA-binding domain MbeD_MobD PF04899.12 KIK43375.1 - 0.084 13.0 0.0 0.3 11.2 0.0 2.0 1 0 0 1 1 1 0 MbeD/MobD like HTH_57 PF18679.1 KIK43375.1 - 0.12 12.7 0.1 0.24 11.7 0.1 1.5 1 0 0 1 1 1 0 ThcOx helix turn helix domain DUF5310 PF17237.2 KIK43376.1 - 5.1e-20 71.1 5.7 6.3e-20 70.8 5.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5310) LRR_6 PF13516.6 KIK43377.1 - 1.7e-14 52.5 8.5 0.017 15.2 0.0 8.1 8 0 0 8 8 8 6 Leucine Rich repeat LRR_4 PF12799.7 KIK43377.1 - 1e-11 44.9 0.3 0.22 12.0 0.0 6.4 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KIK43377.1 - 8.8e-06 25.6 2.6 6.9 7.6 0.0 6.6 7 1 0 7 7 7 2 Leucine Rich Repeat RhoGEF PF00621.20 KIK43379.1 - 9.5e-21 74.8 0.0 1.6e-19 70.8 0.0 2.6 1 1 0 1 1 1 1 RhoGEF domain DUF3482 PF11981.8 KIK43379.1 - 0.086 12.2 0.3 0.15 11.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) RhoGEF PF00621.20 KIK43380.1 - 9.3e-32 110.7 0.0 2.2e-31 109.5 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain LMBR1 PF04791.16 KIK43380.1 - 0.2 10.5 4.0 0.31 9.9 4.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Unstab_antitox PF09720.10 KIK43380.1 - 0.22 11.6 1.8 7.1 6.8 0.1 3.0 2 0 0 2 2 2 0 Putative addiction module component GAS PF13851.6 KIK43380.1 - 0.3 10.4 15.6 0.48 9.7 3.5 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding SYF2 PF08231.12 KIK43380.1 - 2.5 8.5 9.6 7.5 6.9 3.0 3.5 3 0 0 3 3 3 0 SYF2 splicing factor Snapin_Pallidin PF14712.6 KIK43380.1 - 3 8.3 6.7 8.5 6.9 0.5 2.8 2 0 0 2 2 2 0 Snapin/Pallidin Cnn_1N PF07989.11 KIK43380.1 - 5.1 7.3 9.3 1.5 9.0 1.0 3.2 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 Lactamase_B_2 PF12706.7 KIK43381.1 - 9e-11 41.7 0.2 0.00043 19.9 0.0 3.1 1 1 1 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 KIK43381.1 - 4.2e-08 32.7 0.0 8e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 KIK43381.1 - 8e-07 29.3 0.8 1.5e-06 28.4 0.4 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.15 KIK43381.1 - 0.059 12.5 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II THOC7 PF05615.13 KIK43382.1 - 1.9e-35 122.0 4.3 1.9e-35 122.0 4.3 1.7 2 0 0 2 2 2 1 Tho complex subunit 7 PAM2 PF07145.15 KIK43382.1 - 0.0022 17.5 1.9 0.0045 16.6 1.9 1.5 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Taxilin PF09728.9 KIK43382.1 - 0.0035 16.6 4.3 0.0058 15.9 4.3 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Golgin_A5 PF09787.9 KIK43382.1 - 0.028 13.9 9.5 0.055 12.9 9.5 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 V_ATPase_I PF01496.19 KIK43382.1 - 0.038 11.9 0.7 0.053 11.4 0.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Biopterin_H PF00351.21 KIK43382.1 - 0.14 11.2 0.2 0.26 10.3 0.2 1.4 1 1 0 1 1 1 0 Biopterin-dependent aromatic amino acid hydroxylase PIN_8 PF18476.1 KIK43382.1 - 0.16 11.8 4.0 0.29 10.9 4.0 1.4 1 0 0 1 1 1 0 PIN like domain CCDC53 PF10152.9 KIK43382.1 - 3.1 8.2 8.5 71 3.8 8.4 2.5 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex RAP80_UIM PF18282.1 KIK43384.1 - 0.00049 19.8 1.1 0.00049 19.8 1.1 1.8 2 0 0 2 2 2 1 RAP80 N-terminal ubiquitin interaction motif UIM PF02809.20 KIK43384.1 - 0.028 14.3 0.8 0.028 14.3 0.8 2.8 3 0 0 3 3 3 0 Ubiquitin interaction motif Pkinase PF00069.25 KIK43385.1 - 2.1e-60 204.3 0.0 5.6e-41 140.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK43385.1 - 2.3e-27 95.9 0.0 5.1e-23 81.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KIK43385.1 - 4.1e-13 49.5 0.0 7.7e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KIK43385.1 - 1.5e-08 34.3 0.1 0.00046 19.6 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KIK43385.1 - 0.00075 19.5 0.4 0.0048 16.8 0.1 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KIK43385.1 - 0.0029 17.3 0.0 1 9.0 0.0 2.4 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIK43385.1 - 0.0057 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIK43385.1 - 0.014 14.3 0.0 0.014 14.3 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain RIO1 PF01163.22 KIK43385.1 - 0.024 14.2 0.5 0.1 12.2 0.0 2.1 2 0 0 2 2 2 0 RIO1 family PAS_9 PF13426.7 KIK43385.1 - 0.051 13.8 0.0 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 PAS domain Seadorna_VP7 PF07387.11 KIK43385.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Ribosomal_S18 PF01084.20 KIK43386.1 - 5.5e-14 52.1 0.2 8.4e-14 51.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S18 Arm-DNA-bind_2 PF12167.8 KIK43387.1 - 0.074 13.0 0.0 0.099 12.6 0.0 1.1 1 0 0 1 1 1 0 Arm DNA-binding domain JAB PF01398.21 KIK43388.1 - 6.2e-34 116.5 0.3 1e-33 115.8 0.3 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KIK43388.1 - 5.1e-12 46.2 0.8 9.8e-12 45.3 0.8 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KIK43388.1 - 2.9e-06 27.0 0.0 4.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 KIK43388.1 - 0.084 12.9 0.6 0.2 11.7 0.6 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF5624 PF18538.1 KIK43388.1 - 0.12 12.5 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) MgtE PF01769.16 KIK43390.1 - 0.051 14.0 0.4 0.18 12.2 0.4 2.0 1 0 0 1 1 1 0 Divalent cation transporter HEAT_EZ PF13513.6 KIK43390.1 - 0.074 13.6 2.4 0.31 11.6 1.1 2.9 2 0 0 2 2 2 0 HEAT-like repeat Vps52 PF04129.12 KIK43391.1 - 2.4e-62 211.3 0.5 1.1e-34 120.1 0.0 3.0 3 0 0 3 3 3 3 Vps52 / Sac2 family Sec3_C PF09763.9 KIK43391.1 - 6.3e-06 24.9 0.0 0.00066 18.2 0.3 2.3 1 1 1 2 2 2 2 Exocyst complex component Sec3 CRR7 PF12095.8 KIK43391.1 - 0.015 15.8 2.5 0.31 11.5 0.2 2.7 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 Skp1_POZ PF03931.15 KIK43391.1 - 0.027 14.6 0.0 0.061 13.5 0.0 1.6 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain F-box PF00646.33 KIK43392.1 - 0.039 13.8 1.6 0.073 13.0 0.2 2.3 2 1 0 2 2 2 0 F-box domain HHH_7 PF14635.6 KIK43392.1 - 0.055 13.8 0.0 0.096 13.0 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif IBN_N PF03810.19 KIK43394.1 - 3.3e-07 30.1 0.0 3.2e-05 23.8 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KIK43394.1 - 0.017 15.5 1.1 0.069 13.6 0.0 2.7 4 0 0 4 4 4 0 HEAT repeats Xpo1 PF08389.12 KIK43394.1 - 0.028 14.5 1.1 0.2 11.7 0.0 2.8 2 0 0 2 2 2 0 Exportin 1-like protein HEAT PF02985.22 KIK43394.1 - 0.089 13.1 0.3 8.4 7.0 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat MS_channel PF00924.18 KIK43396.1 - 1.6e-18 67.0 0.6 3.3e-18 66.0 0.6 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KIK43396.1 - 1e-05 24.7 0.2 3e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KIK43396.1 - 0.0001 22.0 0.1 0.00055 19.7 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KIK43396.1 - 0.0009 18.6 0.1 0.0049 16.3 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KIK43396.1 - 0.0021 18.4 0.0 0.005 17.3 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair DUF3098 PF11297.8 KIK43396.1 - 0.073 12.7 1.1 0.17 11.5 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) PBP1_TM PF14812.6 KIK43396.1 - 3.1 8.2 7.3 0.81 10.1 1.5 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mur_ligase_M PF08245.12 KIK43397.1 - 4.9e-06 26.7 0.0 0.00015 21.9 0.0 2.3 1 1 1 2 2 2 2 Mur ligase middle domain BRCT_2 PF16589.5 KIK43398.1 - 1.4e-05 25.4 0.0 3.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KIK43398.1 - 4.6e-05 23.7 0.0 0.00011 22.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KIK43398.1 - 0.0011 19.3 0.0 0.0023 18.2 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain LPAM_1 PF08139.12 KIK43398.1 - 0.2 12.2 0.1 0.37 11.4 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Hist_deacetyl PF00850.19 KIK43399.1 - 3.2e-52 177.9 0.1 4.4e-52 177.5 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Pex24p PF06398.11 KIK43400.1 - 5.5e-26 91.4 14.2 3.3e-19 69.1 0.2 2.1 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin WD40 PF00400.32 KIK43401.1 - 2.3e-30 104.2 20.4 7.9e-07 29.7 0.3 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43401.1 - 4e-14 52.7 0.6 0.0028 17.9 0.0 5.6 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KIK43401.1 - 5.6e-05 22.6 0.7 0.64 9.3 0.1 4.0 2 2 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal DUF1199 PF06712.11 KIK43401.1 - 0.11 12.6 1.2 0.31 11.1 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1199) Ge1_WD40 PF16529.5 KIK43401.1 - 0.12 11.4 0.0 34 3.2 0.0 3.4 2 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK43401.1 - 0.14 12.2 5.5 20 5.3 0.0 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 KIK43402.1 - 1.9e-32 110.7 17.9 4.5e-06 27.3 0.4 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43402.1 - 7.4e-17 61.4 0.2 2.8e-05 24.3 0.0 5.8 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KIK43402.1 - 0.00057 19.3 0.1 10 5.4 0.0 4.1 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 KIK43402.1 - 0.025 13.5 0.0 9.7 5.0 0.0 3.4 4 1 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK43402.1 - 1.1 9.2 15.1 5.7 7.0 0.8 5.0 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat CsbD PF05532.12 KIK43403.1 - 0.00083 19.2 0.4 0.0021 17.9 0.4 1.6 1 0 0 1 1 1 1 CsbD-like GST_N_3 PF13417.6 KIK43404.1 - 2.6e-12 46.9 0.1 9.5e-12 45.2 0.1 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK43404.1 - 4.2e-09 36.6 0.0 8.4e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIK43404.1 - 0.009 16.2 0.0 0.027 14.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIK43404.1 - 0.014 15.6 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK43404.1 - 0.019 15.0 0.1 0.044 13.8 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIK43405.1 - 3.8e-11 43.2 0.0 7e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK43405.1 - 5.2e-11 42.7 0.0 8.9e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK43405.1 - 0.00032 20.7 0.0 0.00059 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIK43405.1 - 0.0033 17.6 0.0 0.006 16.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK43405.1 - 0.0034 17.6 0.0 0.0066 16.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KIK43405.1 - 0.0052 17.1 0.0 0.033 14.5 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DEAD PF00270.29 KIK43407.1 - 9.8e-20 71.0 0.0 1.8e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK43407.1 - 4.8e-14 52.6 0.0 2e-11 44.2 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KIK43407.1 - 2.3e-11 44.3 2.2 4.2e-11 43.4 0.5 2.4 2 0 0 2 2 2 1 RecQ zinc-binding AAA_22 PF13401.6 KIK43407.1 - 0.067 13.5 0.0 0.7 10.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain CN_hydrolase PF00795.22 KIK43408.1 - 1.6e-15 57.2 0.0 2.7e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FYRN PF05964.14 KIK43409.1 - 1.8e-18 66.1 0.2 5.3e-18 64.6 0.3 1.7 2 0 0 2 2 2 1 F/Y-rich N-terminus FYRC PF05965.14 KIK43409.1 - 5.2e-16 58.6 0.0 1.6e-15 57.0 0.0 1.8 2 0 0 2 2 2 1 F/Y rich C-terminus ZapB PF06005.12 KIK43409.1 - 0.00035 21.0 3.9 0.00035 21.0 3.9 1.7 2 0 0 2 2 2 1 Cell division protein ZapB Laminin_II PF06009.12 KIK43409.1 - 0.0093 16.0 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Laminin Domain II DASH_Dad3 PF08656.10 KIK43409.1 - 0.029 14.4 1.2 0.056 13.5 1.2 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad3 PAS_3 PF08447.12 KIK43410.1 - 3.1e-08 33.8 0.0 5.6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 KIK43410.1 - 0.00019 21.5 0.0 0.0019 18.3 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KIK43410.1 - 0.00052 20.0 0.0 0.0012 18.8 0.0 1.6 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 KIK43410.1 - 0.0045 17.2 0.0 0.12 12.6 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KIK43410.1 - 0.049 13.9 0.0 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 PAS fold GCD14 PF08704.10 KIK43411.1 - 2e-90 302.8 0.0 3.6e-90 301.9 0.0 1.4 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 KIK43411.1 - 8.3e-05 22.4 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIK43411.1 - 0.0001 22.2 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KIK43411.1 - 0.011 16.4 0.0 0.023 15.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain BHD_3 PF10405.9 KIK43412.1 - 3.6e-29 101.0 0.4 7.7e-29 99.9 0.4 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 KIK43412.1 - 5e-22 78.2 0.0 1.3e-21 76.9 0.0 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_2 PF10404.9 KIK43412.1 - 3.4e-18 66.3 1.1 3.4e-18 66.3 1.1 2.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.9 KIK43412.1 - 5.7e-18 64.5 0.0 1.3e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 KIK43412.1 - 1.1e-06 29.1 0.0 1.1e-05 25.8 0.0 2.6 1 1 0 1 1 1 1 Transglutaminase-like superfamily zf-MYND PF01753.18 KIK43413.1 - 2.1e-07 30.9 15.9 5.1e-07 29.7 15.9 1.7 1 0 0 1 1 1 1 MYND finger DUF1979 PF09322.10 KIK43413.1 - 0.16 11.9 0.0 0.48 10.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1979) zf-C6H2 PF15801.5 KIK43413.1 - 8 6.9 10.2 18 5.8 10.2 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding BTB PF00651.31 KIK43414.1 - 1.7e-06 28.2 0.1 4.2e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.25 KIK43416.1 - 1e-46 159.5 0.0 1.3e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK43416.1 - 3.7e-24 85.4 0.0 1.5e-23 83.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK43416.1 - 2.2e-05 23.9 0.0 3.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIK43416.1 - 3.4e-05 23.9 0.0 6.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK43416.1 - 0.0013 17.6 0.0 0.0045 15.8 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 KIK43416.1 - 0.0038 16.8 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KIK43416.1 - 0.091 12.3 0.1 0.28 10.7 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase FTA2 PF13095.6 KIK43416.1 - 0.11 12.1 0.0 0.73 9.4 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 WD40 PF00400.32 KIK43417.1 - 9.9e-26 89.5 25.3 1.8e-05 25.4 0.4 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43417.1 - 1.2e-17 64.0 1.4 5.5e-05 23.4 0.1 5.7 2 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK43417.1 - 0.0023 17.8 7.5 2.4 8.2 0.0 5.1 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat WD40 PF00400.32 KIK43418.1 - 7.7e-27 93.0 12.0 7.5e-05 23.4 0.1 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43418.1 - 1.1e-12 48.1 0.3 0.009 16.3 0.0 5.7 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK43418.1 - 0.0055 16.6 2.0 1.5 8.8 0.0 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat WD40 PF00400.32 KIK43419.1 - 1.3e-31 108.2 14.7 3.8e-06 27.5 0.1 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43419.1 - 1.7e-14 53.9 0.0 8.1e-05 22.8 0.0 5.2 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK43419.1 - 6e-06 26.1 5.5 1.8 8.6 0.0 5.0 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK43419.1 - 0.0028 16.7 0.0 6.4 5.6 0.0 3.8 2 2 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK43419.1 - 0.1 11.9 0.0 3.6 6.8 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain WD40 PF00400.32 KIK43422.1 - 4.1e-35 119.2 8.8 8.6e-08 32.7 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43422.1 - 2.1e-12 47.2 0.1 0.006 16.9 0.0 5.0 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK43422.1 - 0.0002 20.4 0.1 0.33 9.8 0.0 3.1 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TFIIIC_delta PF12657.7 KIK43422.1 - 0.024 14.5 0.0 0.062 13.2 0.0 1.6 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term MFS_1 PF07690.16 KIK43423.1 - 8.7e-47 159.7 16.6 8.7e-47 159.7 16.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK43423.1 - 8e-14 51.3 14.6 2.5e-12 46.4 0.2 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 KIK43423.1 - 0.00011 20.7 1.0 0.00025 19.5 0.2 2.1 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Pkinase PF00069.25 KIK43425.1 - 2.3e-29 102.6 0.0 1.9e-14 53.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK43425.1 - 1.1e-12 47.8 0.0 2.9e-07 30.0 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KIK43425.1 - 0.1 11.6 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase WD40 PF00400.32 KIK43426.1 - 3.7e-23 81.4 18.0 0.00021 22.0 0.1 7.9 7 1 1 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43426.1 - 1.5e-14 54.0 0.5 0.0007 19.8 0.0 5.4 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK43426.1 - 0.0019 18.1 3.3 40 4.3 0.0 4.6 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat p450 PF00067.22 KIK43428.1 - 3.2e-75 253.6 0.0 3.8e-75 253.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mersacidin PF16934.5 KIK43428.1 - 0.19 11.5 1.6 0.64 9.8 0.6 2.2 1 1 1 2 2 2 0 Two-component Enterococcus faecalis cytolysin (EFC) CR6_interact PF10147.9 KIK43431.1 - 0.005 16.6 1.1 0.0051 16.5 1.1 1.1 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Peptidase_S49_N PF08496.10 KIK43431.1 - 0.21 11.6 3.1 0.24 11.5 3.1 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SH3_9 PF14604.6 KIK43435.1 - 1.1e-06 28.4 0.0 1.7e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIK43435.1 - 6.9e-06 25.6 0.0 1.3e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 SH3 domain WIYLD PF10440.9 KIK43435.1 - 0.046 13.5 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain UPF0506 PF11703.8 KIK43437.1 - 0.03 14.7 1.5 0.036 14.4 1.5 1.2 1 0 0 1 1 1 0 UPF0506 WD40 PF00400.32 KIK43440.1 - 6.2e-42 140.8 16.8 7.1e-08 33.0 1.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43440.1 - 1.2e-14 54.3 6.2 0.0013 18.9 0.1 6.0 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK43440.1 - 2.3e-06 26.8 0.1 0.33 9.8 0.1 4.2 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK43440.1 - 1.4e-05 24.6 0.2 0.00012 21.5 0.0 2.4 1 1 1 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK43440.1 - 0.00019 20.2 4.7 1.8 7.1 0.3 4.1 1 1 0 4 4 4 2 Nucleoporin Nup120/160 Mucin PF01456.17 KIK43440.1 - 0.012 15.6 5.6 0.012 15.6 5.6 2.8 2 1 1 3 3 3 0 Mucin-like glycoprotein Cytochrom_D1 PF02239.16 KIK43440.1 - 0.018 13.6 0.0 0.69 8.4 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 KIK43440.1 - 0.051 12.3 0.0 5.4 5.7 0.0 2.5 2 1 0 2 2 2 0 Nup133 N terminal like GNAT_like PF18407.1 KIK43441.1 - 0.017 15.4 0.0 0.019 15.3 0.0 1.1 1 0 0 1 1 1 0 GCN5-related N-acetyltransferase like domain DUF2768 PF10966.8 KIK43445.1 - 0.057 13.9 0.3 0.1 13.1 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2768) Cyt_bd_oxida_II PF02322.15 KIK43447.1 - 0.0013 18.2 6.7 0.0015 17.9 6.7 1.1 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II DUF3169 PF11368.8 KIK43447.1 - 0.011 15.2 0.2 0.13 11.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) LAL_C2 PF18603.1 KIK43448.1 - 0.081 13.1 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 WD40 PF00400.32 KIK43449.1 - 2.5e-26 91.4 13.3 2e-07 31.5 1.9 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43449.1 - 4.9e-16 58.8 1.7 7.2e-06 26.2 0.1 4.4 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK43449.1 - 1.2e-05 24.1 0.6 0.14 10.8 0.6 3.5 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK43449.1 - 3.4e-05 23.0 0.0 0.11 11.4 0.0 3.0 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK43449.1 - 9.3e-05 22.4 0.6 0.038 13.9 0.1 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KIK43449.1 - 0.0016 17.8 0.3 0.046 13.0 0.0 2.8 1 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.9 KIK43449.1 - 0.0074 16.1 2.1 0.01 15.6 1.2 1.7 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain DUF4082 PF13313.6 KIK43449.1 - 0.0086 16.1 1.7 0.096 12.7 0.8 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4082) WD40_like PF17005.5 KIK43449.1 - 0.058 12.7 0.0 0.25 10.6 0.0 2.1 2 1 0 2 2 2 0 WD40-like domain WD40 PF00400.32 KIK43450.1 - 4.5e-11 43.1 0.6 2.8e-09 37.4 0.1 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43450.1 - 0.023 15.0 0.0 0.18 12.1 0.0 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK43450.1 - 0.06 13.3 0.0 0.97 9.5 0.0 2.1 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK43450.1 - 0.11 11.4 0.0 1.6 7.6 0.0 2.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Piwi PF02171.17 KIK43452.1 - 4.6e-75 252.7 0.0 7.7e-55 186.3 0.0 2.1 2 0 0 2 2 2 2 Piwi domain ArgoN PF16486.5 KIK43452.1 - 1.9e-20 73.9 0.0 4e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 KIK43452.1 - 2.9e-13 49.8 0.0 5.1e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 KIK43452.1 - 3.5e-13 49.0 0.1 1.2e-12 47.3 0.1 2.0 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KIK43452.1 - 1.5e-10 41.3 0.0 7.9e-10 38.9 0.0 2.2 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoMid PF16487.5 KIK43452.1 - 0.0046 17.2 0.1 0.014 15.7 0.1 1.8 1 0 0 1 1 1 1 Mid domain of argonaute CNRIP1 PF15043.6 KIK43452.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 CB1 cannabinoid receptor-interacting protein 1 SPT6_acidic PF14632.6 KIK43453.1 - 0.1 13.2 4.9 0.11 13.0 4.9 1.1 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Cyt_bd_oxida_II PF02322.15 KIK43456.1 - 0.00052 19.5 5.7 0.00064 19.2 5.7 1.2 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II DUF3169 PF11368.8 KIK43456.1 - 0.025 14.1 1.0 0.23 10.9 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) DUF2484 PF10658.9 KIK43456.1 - 2.9 8.3 6.1 23 5.4 1.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2484) DUF4059 PF13268.6 KIK43457.1 - 0.24 11.8 3.3 1.2 9.5 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) Cyt_bd_oxida_II PF02322.15 KIK43457.1 - 1.2 8.4 11.7 1.8 7.9 11.4 1.5 1 1 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Aldedh PF00171.22 KIK43458.1 - 2.8e-182 606.3 0.8 3.2e-182 606.2 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KIK43458.1 - 0.0047 16.4 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) AhpC-TSA PF00578.21 KIK43460.1 - 8.4e-25 87.1 0.0 9.5e-25 86.9 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIK43460.1 - 3.8e-16 59.1 0.0 4.4e-16 58.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin LRR_6 PF13516.6 KIK43461.1 - 5.9e-13 47.7 26.8 0.019 15.0 0.0 8.9 9 0 0 9 9 9 6 Leucine Rich repeat LRR_4 PF12799.7 KIK43461.1 - 0.0024 18.2 26.4 0.098 13.1 1.2 6.2 5 2 3 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KIK43461.1 - 0.0072 16.7 14.6 14 6.7 0.2 7.6 9 0 0 9 9 9 2 Leucine Rich Repeat LRR_8 PF13855.6 KIK43461.1 - 0.031 14.0 24.2 0.44 10.3 1.1 6.5 5 2 0 5 5 5 0 Leucine rich repeat GST_N_3 PF13417.6 KIK43462.1 - 5.7e-06 26.6 0.0 1.1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK43462.1 - 8.9e-06 25.9 0.2 1.7e-05 25.1 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK43462.1 - 0.00017 21.6 1.5 0.00022 21.2 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK43462.1 - 0.0062 16.7 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIK43462.1 - 0.0066 16.6 0.0 0.014 15.6 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain ATG13 PF10033.9 KIK43464.1 - 1.5e-49 168.9 0.0 2e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 Glyco_hydro_18 PF00704.28 KIK43465.1 - 5.9e-24 85.4 3.5 1.3e-23 84.3 3.5 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 FSA_C PF10479.9 KIK43465.1 - 0.26 9.4 13.5 0.42 8.7 13.5 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Sporozoite_P67 PF05642.11 KIK43465.1 - 0.5 8.4 10.2 0.75 7.8 10.2 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.17 KIK43465.1 - 0.68 9.9 42.3 0.029 14.4 36.3 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein PAP1 PF08601.10 KIK43465.1 - 3.5 7.3 8.6 5.3 6.7 8.6 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Glyco_hydro_18 PF00704.28 KIK43466.1 - 1.3e-22 80.9 6.4 3.7e-22 79.4 6.4 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 PTR2 PF00854.21 KIK43468.1 - 4.9e-15 55.3 0.9 7.1e-15 54.7 0.3 1.5 1 1 1 2 2 2 1 POT family Phage_holin_3_6 PF07332.11 KIK43468.1 - 0.012 15.7 1.9 0.015 15.3 1.9 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III MFS_1 PF07690.16 KIK43468.1 - 0.034 13.1 8.7 0.059 12.3 3.4 2.0 1 1 1 2 2 2 0 Major Facilitator Superfamily PTR2 PF00854.21 KIK43470.1 - 1e-80 271.5 8.6 1.3e-80 271.2 8.6 1.1 1 0 0 1 1 1 1 POT family Phage_holin_3_6 PF07332.11 KIK43470.1 - 0.4 10.7 8.9 0.16 12.0 1.1 3.0 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III SKN1 PF03935.15 KIK43471.1 - 2.9e-186 619.8 1.8 4.3e-186 619.2 1.8 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF2477 PF10631.9 KIK43473.1 - 0.11 13.2 2.1 0.18 12.5 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2477) WD40 PF00400.32 KIK43474.1 - 6.1e-39 131.3 22.2 2.1e-06 28.4 4.2 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43474.1 - 9.7e-17 61.1 4.8 0.002 18.4 0.1 6.2 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK43474.1 - 8e-07 28.1 6.4 0.017 13.8 0.5 4.2 2 1 3 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK43474.1 - 0.00022 20.7 0.0 0.68 9.2 0.0 3.6 2 2 1 4 4 4 2 WD40-like domain Cytochrom_D1 PF02239.16 KIK43474.1 - 0.0011 17.6 0.1 2 6.8 0.1 2.8 1 1 1 3 3 3 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KIK43474.1 - 0.015 14.3 0.2 24 3.8 0.0 4.1 1 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Glyco_hydro_18 PF00704.28 KIK43475.1 - 4.8e-21 75.8 4.5 1.1e-20 74.6 4.5 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12_2 PF14600.6 KIK43475.1 - 0.00026 20.9 0.3 0.0011 18.8 0.3 2.1 1 0 0 1 1 1 1 Cellulose-binding domain CBM_5_12 PF02839.14 KIK43475.1 - 0.00037 20.9 3.3 0.00037 20.9 3.3 2.8 2 0 0 2 2 2 1 Carbohydrate binding domain Fim-adh_lectin PF09222.10 KIK43477.1 - 0.035 13.6 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Fimbrial adhesin F17-AG, lectin domain Thioredoxin_4 PF13462.6 KIK43480.1 - 3.8e-11 43.4 0.0 9.1e-11 42.2 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 KIK43480.1 - 0.035 13.9 0.4 0.19 11.5 0.1 2.2 2 1 1 3 3 3 0 DSBA-like thioredoxin domain Aminotran_1_2 PF00155.21 KIK43481.1 - 8e-87 291.7 0.0 9.1e-87 291.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Arb1 PF09692.10 KIK43482.1 - 1.5e-06 27.7 0.0 2.9e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 zf-CCCH_4 PF18044.1 KIK43483.1 - 5.7e-05 22.8 4.0 9.7e-05 22.1 4.0 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KIK43483.1 - 0.00023 21.0 2.5 0.00039 20.3 2.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIK43483.1 - 0.0012 18.8 6.7 0.002 18.1 6.7 1.4 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KIK43483.1 - 0.068 13.9 1.1 0.16 12.7 1.1 1.6 1 0 0 1 1 1 0 Torus domain Glyco_hydro_53 PF07745.13 KIK43484.1 - 0.023 13.7 0.1 0.028 13.4 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 Med15_fungi PF05397.12 KIK43484.1 - 0.025 14.8 0.7 0.048 13.9 0.7 1.4 1 0 0 1 1 1 0 Mediator complex subunit 15 Ribosomal_L31e PF01198.19 KIK43484.1 - 0.043 14.0 0.0 3.2 8.0 0.0 2.5 1 1 1 2 2 2 0 Ribosomal protein L31e EF-G-binding_N PF07299.11 KIK43484.1 - 0.093 13.3 0.4 0.16 12.5 0.4 1.3 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal HisKA_3 PF07730.13 KIK43484.1 - 0.19 12.3 0.4 39 4.9 0.0 3.4 3 1 1 4 4 4 0 Histidine kinase Ifi-6-16 PF06140.13 KIK43485.1 - 8.8e-05 22.3 0.0 0.00039 20.3 0.0 2.0 3 0 0 3 3 3 1 Interferon-induced 6-16 family Ifi-6-16 PF06140.13 KIK43486.1 - 5.8e-09 35.8 0.4 9.9e-09 35.0 0.1 1.5 2 0 0 2 2 2 1 Interferon-induced 6-16 family SdpI PF13630.6 KIK43486.1 - 0.087 13.0 2.3 3.5 7.8 0.0 2.8 2 1 0 2 2 2 0 SdpI/YhfL protein family PARP_reg PF02877.14 KIK43487.1 - 3.2e-05 24.1 1.2 0.047 13.8 0.3 3.4 1 1 2 3 3 3 2 Poly(ADP-ribose) polymerase, regulatory domain DUF2564 PF10819.8 KIK43487.1 - 0.0025 18.1 10.5 0.19 12.1 1.4 3.8 2 1 2 4 4 4 3 Protein of unknown function (DUF2564) DUF3077 PF11275.8 KIK43487.1 - 0.0064 16.7 2.5 28 5.0 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3077) YhfZ_C PF14503.6 KIK43487.1 - 0.027 14.0 0.1 0.1 12.1 0.1 1.8 1 1 1 2 2 2 0 YhfZ C-terminal domain SH3BP5 PF05276.14 KIK43487.1 - 0.034 13.9 2.2 0.16 11.8 0.4 2.1 1 1 1 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) RNase_J_C PF17770.1 KIK43487.1 - 0.057 14.5 1.7 8.1 7.6 0.1 3.3 1 1 3 4 4 4 0 Ribonuclease J C-terminal domain DUF3347 PF11827.8 KIK43487.1 - 0.11 12.7 1.0 4.9 7.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) FIVAR PF07554.13 KIK43487.1 - 0.23 12.3 12.5 1.7 9.4 0.3 4.0 3 1 1 4 4 4 0 FIVAR domain DUF1002 PF06207.11 KIK43487.1 - 0.34 10.4 4.0 1.3 8.5 3.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1002) Mrr_cat_2 PF13156.6 KIK43487.1 - 0.7 9.8 5.6 0.61 10.0 0.3 3.0 1 1 3 4 4 4 0 Restriction endonuclease Ifi-6-16 PF06140.13 KIK43488.1 - 5.9e-06 26.1 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family Terpene_synth_C PF03936.16 KIK43489.1 - 0.00033 20.1 0.0 0.00056 19.3 0.0 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain WD40 PF00400.32 KIK43490.1 - 1.7e-35 120.4 9.9 3.7e-06 27.6 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43490.1 - 2e-11 44.0 1.1 0.0041 17.4 0.0 4.1 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK43490.1 - 0.0007 18.6 0.0 1.6 7.6 0.0 3.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK43490.1 - 0.0082 16.0 0.0 0.62 9.9 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK43490.1 - 0.021 13.5 1.2 4.2 5.9 0.0 3.0 2 1 0 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK43490.1 - 0.028 13.7 0.0 0.72 9.1 0.0 2.4 2 1 0 2 2 2 0 WD40-like domain Gp_dh_C PF02800.20 KIK43491.1 - 1.1e-07 31.6 0.2 1.1e-06 28.3 0.2 1.9 1 1 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Hid1 PF12722.7 KIK43492.1 - 0.62 8.1 11.4 0.73 7.9 11.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 KIK43492.1 - 0.66 8.7 13.8 0.8 8.4 13.8 1.1 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 KIK43492.1 - 1.2 8.1 10.5 1.6 7.7 10.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 KIK43492.1 - 9.6 4.4 28.0 12 4.0 28.0 1.1 1 0 0 1 1 1 0 CDC45-like protein fn3_2 PF16893.5 KIK43497.1 - 6.1e-39 132.1 0.2 1.4e-38 131.0 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KIK43497.1 - 2.6e-26 91.3 0.1 4.3e-26 90.6 0.1 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 KIK43497.1 - 1.5e-07 31.7 0.0 2.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KIK43497.1 - 3.4e-05 23.7 0.2 0.0014 18.5 0.0 2.9 2 1 0 2 2 2 1 twin BRCT domain fn3 PF00041.21 KIK43497.1 - 0.0011 19.2 0.3 0.0046 17.3 0.3 2.0 1 1 0 1 1 1 1 Fibronectin type III domain BRCT_2 PF16589.5 KIK43497.1 - 0.0018 18.7 0.0 0.0034 17.7 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF3006 PF11213.8 KIK43497.1 - 0.0058 16.8 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) Xan_ur_permease PF00860.20 KIK43498.1 - 3.1e-62 210.5 35.5 4.5e-61 206.7 32.2 2.6 2 1 0 2 2 2 1 Permease family WD40 PF00400.32 KIK43502.1 - 1.5e-23 82.6 4.5 3.1e-10 40.5 0.5 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43502.1 - 0.0003 21.0 0.2 0.25 11.7 0.0 2.3 1 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK43502.1 - 0.0019 18.1 0.0 2 8.4 0.0 2.9 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK43502.1 - 0.26 10.6 0.0 13 5.0 0.0 2.3 2 1 0 2 2 2 0 WD40-like domain Clathrin PF00637.20 KIK43503.1 - 6.2e-21 74.8 0.4 1.8e-20 73.2 0.1 2.0 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.9 KIK43503.1 - 0.00046 20.6 0.2 0.0036 17.7 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.6 KIK43503.1 - 0.017 15.1 1.5 0.047 13.6 1.5 1.8 1 1 0 1 1 1 0 zinc-RING finger domain ANAPC4_WD40 PF12894.7 KIK43503.1 - 0.044 14.1 0.0 0.26 11.6 0.0 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_2 PF13639.6 KIK43503.1 - 0.052 13.9 5.0 0.065 13.6 1.8 2.4 2 0 0 2 2 2 0 Ring finger domain Zn_ribbon_17 PF17120.5 KIK43503.1 - 0.06 13.0 0.6 0.14 11.8 0.6 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 KIK43503.1 - 2.7 8.1 6.0 0.38 10.8 1.2 2.2 2 0 0 2 2 2 0 Zinc-finger Prok-RING_4 PF14447.6 KIK43503.1 - 4.5 7.2 7.4 5 7.1 0.1 2.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 BUD22 PF09073.10 KIK43503.1 - 4.9 6.4 13.9 9.3 5.5 13.9 1.4 1 0 0 1 1 1 0 BUD22 WW PF00397.26 KIK43505.1 - 0.1 12.7 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 WW domain GRDP-like PF07173.12 KIK43506.1 - 2e-18 67.4 0.0 3.3e-12 47.3 0.0 3.2 2 1 1 3 3 3 3 Glycine-rich domain-containing protein-like HET PF06985.11 KIK43508.1 - 8.1e-09 36.0 5.5 7.7e-07 29.6 1.2 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.11 KIK43509.1 - 2.5e-08 34.4 5.5 3.4e-07 30.7 0.7 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF4279 PF14106.6 KIK43509.1 - 0.027 14.7 0.3 0.16 12.1 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) BCDHK_Adom3 PF10436.9 KIK43509.1 - 0.085 12.7 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase WD40 PF00400.32 KIK43510.1 - 6.9e-26 90.0 20.1 2.1e-08 34.7 0.6 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43510.1 - 8.6e-14 51.6 1.5 8.3e-06 26.0 0.0 4.9 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK43510.1 - 0.00013 21.1 0.5 4.8 6.1 0.0 4.8 2 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KIK43510.1 - 0.00018 20.1 0.0 2.6 6.5 0.0 3.0 3 0 0 3 3 3 2 Cytochrome D1 heme domain eIF2A PF08662.11 KIK43510.1 - 0.00078 19.4 0.2 0.036 13.9 0.0 2.8 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK43510.1 - 0.001 17.9 3.3 0.19 10.4 0.0 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 VID27 PF08553.10 KIK43510.1 - 0.002 17.3 0.0 0.6 9.1 0.0 2.1 1 1 1 2 2 2 2 VID27 C-terminal WD40-like domain Coatomer_WDAD PF04053.14 KIK43510.1 - 0.0047 16.0 0.0 0.0096 15.0 0.0 1.6 1 1 0 1 1 1 1 Coatomer WD associated region PD40 PF07676.12 KIK43510.1 - 0.015 15.2 9.2 45 4.2 0.0 6.0 6 1 0 6 6 6 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK43510.1 - 0.057 12.8 2.5 43 3.3 0.0 4.3 2 1 2 5 5 5 0 Neuroblastoma-amplified sequence, N terminal DUF459 PF04311.13 KIK43510.1 - 0.11 11.5 0.0 0.32 10.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF459) Glu_cyclase_2 PF05096.12 KIK43510.1 - 0.12 11.8 0.1 0.32 10.4 0.0 1.7 2 0 0 2 2 2 0 Glutamine cyclotransferase Ribosomal_L7Ae PF01248.26 KIK43511.1 - 6e-26 90.0 2.6 7.5e-26 89.7 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family TMEM135_C_rich PF15982.5 KIK43512.1 - 0.00076 20.1 3.0 0.082 13.5 1.4 3.3 2 1 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 KIK43512.1 - 0.0051 17.2 6.2 0.29 11.5 0.0 3.6 4 0 0 4 4 4 2 Tim17/Tim22/Tim23/Pmp24 family DUF1173 PF06666.11 KIK43512.1 - 0.12 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1173) TPR_9 PF13371.6 KIK43512.1 - 0.28 11.3 1.7 0.55 10.4 1.7 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Lipase_GDSL_2 PF13472.6 KIK43513.1 - 4.7e-05 23.8 0.0 6.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Aim19 PF10315.9 KIK43514.1 - 2e-19 70.0 0.6 2.7e-19 69.6 0.6 1.2 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Na_H_Exchanger PF00999.21 KIK43521.1 - 1.7e-55 188.3 21.0 2e-55 188.2 21.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 KIK43521.1 - 0.19 11.8 0.0 0.19 11.8 0.0 3.0 4 0 0 4 4 4 0 YrhC-like protein DUF2301 PF10063.9 KIK43522.1 - 0.028 14.8 0.1 0.031 14.7 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) NS3_envE PF02723.14 KIK43523.1 - 0.029 14.4 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E WD40 PF00400.32 KIK43524.1 - 2.7e-22 78.6 3.9 1.3e-06 29.0 0.2 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat PD40 PF07676.12 KIK43524.1 - 0.0018 18.2 0.0 3.2 7.8 0.0 3.6 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 KIK43524.1 - 0.0019 18.5 0.1 11 6.4 0.0 4.2 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK43524.1 - 0.028 13.1 1.4 0.081 11.6 0.0 2.3 3 1 0 3 3 3 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK43524.1 - 0.15 11.0 0.0 0.38 9.7 0.0 1.6 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RasGEF PF00617.19 KIK43526.1 - 5.2e-24 85.4 0.0 1.2e-23 84.2 0.1 1.6 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KIK43526.1 - 3.3e-11 43.4 0.0 9.7e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 KIK43526.1 - 0.0022 17.6 0.0 0.032 13.8 0.0 2.2 2 0 0 2 2 2 1 Ras family RsgA_GTPase PF03193.16 KIK43526.1 - 0.028 14.3 0.2 0.47 10.3 0.1 2.8 3 0 0 3 3 3 0 RsgA GTPase AAA_33 PF13671.6 KIK43526.1 - 0.16 12.1 0.1 0.53 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2486 PF10667.9 KIK43526.1 - 8.9 6.5 7.6 8 6.6 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) SurE PF01975.17 KIK43527.1 - 4.8e-47 160.3 0.0 6.4e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Ribosomal_L15e PF00827.17 KIK43529.1 - 1.2e-90 302.4 9.7 1.3e-90 302.2 9.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 MFS_1 PF07690.16 KIK43531.1 - 8.3e-19 67.7 25.0 8.3e-19 67.7 25.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KIK43531.1 - 4e-06 25.9 0.5 5.8e-06 25.4 0.1 1.6 1 1 0 1 1 1 1 MFS_1 like family UPF0160 PF03690.13 KIK43533.1 - 1.6e-136 455.1 0.0 1.8e-136 454.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DPBB_1 PF03330.18 KIK43536.1 - 0.0031 17.7 0.0 0.0079 16.4 0.0 1.7 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KIK43536.1 - 0.071 13.0 0.3 0.11 12.3 0.3 1.3 1 0 0 1 1 1 0 Barwin family Mucin PF01456.17 KIK43536.1 - 0.13 12.3 25.7 0.23 11.4 25.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein SAD_SRA PF02182.17 KIK43537.1 - 1.5e-53 180.7 0.0 2.1e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 SAD/SRA domain zf-CCCH_4 PF18044.1 KIK43538.1 - 0.0045 16.7 2.6 0.0045 16.7 2.6 4.3 3 1 1 4 4 4 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KIK43538.1 - 0.01 16.1 2.6 0.01 16.1 2.6 2.5 1 1 0 2 2 2 0 Zinc-finger containing family zf-CCCH PF00642.24 KIK43538.1 - 0.041 13.8 22.8 0.7 9.9 1.7 4.7 2 1 2 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KIK43538.1 - 1.7 9.4 10.3 0.29 11.8 0.9 2.5 1 1 1 2 2 2 0 Torus domain Lustrin_cystein PF14625.6 KIK43538.1 - 2.4 8.6 16.5 18 5.8 11.5 3.0 2 1 0 2 2 2 0 Lustrin, cysteine-rich repeated domain NICE-3 PF07406.11 KIK43539.1 - 0.054 13.5 1.4 0.085 12.8 0.9 1.6 1 1 0 1 1 1 0 NICE-3 protein V-SNARE_C PF12352.8 KIK43539.1 - 0.31 11.4 7.4 2.5 8.5 0.4 2.8 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Mpp10 PF04006.12 KIK43540.1 - 8.7e-117 391.1 37.5 1.1e-116 390.7 37.5 1.0 1 0 0 1 1 1 1 Mpp10 protein DHHC PF01529.20 KIK43541.1 - 0.083 13.0 10.9 0.39 10.8 0.8 2.9 2 1 0 2 2 2 0 DHHC palmitoyltransferase DUF4006 PF13179.6 KIK43541.1 - 0.47 10.4 5.9 1.7 8.6 0.2 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Yip1 PF04893.17 KIK43541.1 - 1.2 8.9 17.7 0.33 10.7 11.4 2.2 2 0 0 2 2 2 0 Yip1 domain DUF4064 PF13273.6 KIK43541.1 - 5 7.5 12.3 0.24 11.7 3.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Lyase_8 PF02278.18 KIK43542.1 - 2.3e-66 223.9 5.2 4.3e-66 223.0 5.2 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 KIK43542.1 - 4.4e-17 62.0 0.1 6.9e-17 61.4 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 KIK43542.1 - 5.3e-09 36.4 0.1 1.3e-08 35.2 0.1 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Ribosomal_S3_C PF00189.20 KIK43543.1 - 6.1e-25 87.5 0.1 2.3e-24 85.7 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KIK43543.1 - 8.7e-12 44.7 0.0 1.5e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 KIK43543.1 - 0.076 13.5 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 KIK43543.1 - 0.14 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Coilin N-terminus Amidase PF01425.21 KIK43544.1 - 1.2e-106 357.4 0.0 1.8e-106 356.9 0.0 1.3 1 0 0 1 1 1 1 Amidase Thiolase_N PF00108.23 KIK43545.1 - 1.1e-63 215.0 0.2 1.5e-63 214.6 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIK43545.1 - 1.9e-40 137.3 1.4 2.7e-40 136.8 0.2 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIK43545.1 - 0.0016 18.0 0.5 0.0075 15.9 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KIK43545.1 - 0.017 15.0 1.9 0.83 9.5 0.2 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAE1_CUT1_RppA PF08392.12 KIK43545.1 - 0.086 12.1 0.1 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 FAE1/Type III polyketide synthase-like protein Baculo_RING PF05883.11 KIK43545.1 - 0.15 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Elong_Iki1 PF10483.9 KIK43547.1 - 5e-10 39.4 0.0 4.9e-09 36.1 0.0 2.3 1 1 0 1 1 1 1 Elongator subunit Iki1 Acetyltransf_1 PF00583.25 KIK43548.1 - 2.2e-07 31.1 0.0 3.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK43548.1 - 0.00013 21.9 0.0 0.0062 16.5 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIK43548.1 - 0.0069 16.1 0.0 0.052 13.2 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK43548.1 - 0.031 14.7 0.0 0.14 12.6 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KIK43548.1 - 0.078 12.4 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 KIK43548.1 - 0.098 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DLH PF01738.18 KIK43549.1 - 1.3e-22 80.4 0.0 1.6e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF2048 PF09752.9 KIK43549.1 - 0.00086 18.5 0.0 0.0028 16.8 0.0 1.7 2 0 0 2 2 2 1 Abhydrolase domain containing 18 LIDHydrolase PF10230.9 KIK43549.1 - 0.0065 16.0 0.0 0.0084 15.7 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase GTP_EFTU PF00009.27 KIK43550.1 - 2.3e-53 180.6 0.0 4.2e-53 179.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KIK43550.1 - 2.2e-42 143.9 0.0 4.6e-42 142.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KIK43550.1 - 4.8e-14 52.5 3.0 5.4e-14 52.3 1.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIK43550.1 - 0.0014 18.7 0.1 0.032 14.3 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase NIF3 PF01784.18 KIK43550.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) Pkinase PF00069.25 KIK43551.1 - 1.6e-39 135.9 0.0 7.4e-38 130.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK43551.1 - 1.2e-14 54.2 0.0 1.3e-13 50.8 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK43551.1 - 0.00074 18.9 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIK43551.1 - 0.0023 17.9 0.1 0.0035 17.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK43551.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KIK43551.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L32e PF01655.18 KIK43552.1 - 1.1e-52 177.0 2.1 1.3e-52 176.8 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Memo PF01875.17 KIK43553.1 - 1.8e-68 230.6 0.0 2.3e-68 230.3 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein HABP4_PAI-RBP1 PF04774.15 KIK43554.1 - 5.5e-08 33.7 15.1 5.5e-08 33.7 15.1 3.0 2 1 0 2 2 2 1 Hyaluronan / mRNA binding family API5 PF05918.11 KIK43554.1 - 3.8 6.2 10.7 4.2 6.1 1.3 2.3 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) PHD PF00628.29 KIK43556.1 - 0.00014 21.6 3.3 0.00014 21.6 3.3 2.7 2 0 0 2 2 2 1 PHD-finger zf-CpG_bind_C PF12269.8 KIK43556.1 - 0.00089 19.1 0.5 0.00089 19.1 0.5 2.3 3 0 0 3 3 3 1 CpG binding protein zinc finger C terminal domain LSM PF01423.22 KIK43557.1 - 1.8e-18 65.9 0.0 2.6e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KIK43557.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Hfq protein His_Phos_1 PF00300.22 KIK43558.1 - 8.7e-22 77.8 0.0 1.1e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ETC_C1_NDUFA5 PF04716.14 KIK43559.1 - 1.5e-26 92.0 0.0 2.2e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Ribosomal_L32p PF01783.23 KIK43560.1 - 1.9e-16 60.0 4.9 3.2e-16 59.3 4.9 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family Prok-RING_1 PF14446.6 KIK43560.1 - 0.0019 18.1 0.2 0.0035 17.3 0.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 DUF3657 PF12394.8 KIK43561.1 - 0.1 13.2 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein FAM135 Aminotran_1_2 PF00155.21 KIK43563.1 - 4.7e-90 302.4 0.0 5.4e-90 302.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II tRNA-synt_2 PF00152.20 KIK43564.1 - 1.3e-74 251.1 0.0 2e-74 250.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIK43564.1 - 4.7e-08 32.9 0.0 8.4e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KIK43564.1 - 0.0085 15.6 3.4 1.4 8.4 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) RNA_pol_Rpc4 PF05132.14 KIK43564.1 - 3.2 8.2 8.1 5.8 7.3 8.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 SPRY PF00622.28 KIK43565.1 - 3.6e-18 65.8 0.0 5.9e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 SPRY domain CBS PF00571.28 KIK43566.1 - 5.9e-21 74.7 3.7 6.6e-10 39.3 0.1 4.7 4 1 0 4 4 4 4 CBS domain Retrotrans_gag PF03732.17 KIK43567.1 - 3.4e-07 30.4 0.1 6.6e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein Macoilin PF09726.9 KIK43567.1 - 0.0043 15.7 3.2 0.0048 15.5 3.2 1.2 1 0 0 1 1 1 1 Macoilin family CDC45 PF02724.14 KIK43567.1 - 0.0056 15.0 5.2 0.0059 15.0 5.2 1.1 1 0 0 1 1 1 1 CDC45-like protein Ndc1_Nup PF09531.10 KIK43567.1 - 0.023 13.4 2.8 0.028 13.1 2.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.22 KIK43567.1 - 0.11 11.7 0.6 0.1 11.8 0.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Apt1 PF10351.9 KIK43567.1 - 0.14 11.0 12.0 0.23 10.3 12.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain NAM-associated PF14303.6 KIK43567.1 - 0.18 12.5 16.3 0.3 11.8 16.3 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain CCDC106 PF15794.5 KIK43567.1 - 0.46 10.1 22.0 0.73 9.5 22.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Neur_chan_memb PF02932.16 KIK43567.1 - 0.9 9.6 5.8 1.3 9.0 5.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 KIK43567.1 - 0.98 8.1 10.7 1.3 7.7 10.7 1.1 1 0 0 1 1 1 0 Presenilin SRP72 PF08492.12 KIK43567.1 - 1.1 9.7 16.8 1.7 9.1 4.7 3.6 3 0 0 3 3 3 0 SRP72 RNA-binding domain DUF4614 PF15391.6 KIK43567.1 - 2.2 8.3 19.3 3.4 7.6 19.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) CAML PF14963.6 KIK43567.1 - 2.3 8.3 6.7 3.5 7.7 6.7 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DHHW PF14286.6 KIK43567.1 - 2.8 7.2 5.2 4 6.7 5.2 1.2 1 0 0 1 1 1 0 DHHW protein DUF5427 PF10310.9 KIK43567.1 - 2.8 6.8 16.5 2.8 6.8 12.6 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5427) DUF3381 PF11861.8 KIK43567.1 - 5.1 6.9 12.4 9.4 6.0 12.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) NPR3 PF03666.13 KIK43567.1 - 8.2 5.1 16.5 12 4.6 16.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.7 KIK43567.1 - 9.3 4.2 10.3 15 3.5 10.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AAA_21 PF13304.6 KIK43568.1 - 0.059 13.2 0.9 0.068 13.0 0.9 1.0 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KIK43569.1 - 1.8e-29 103.0 0.0 1.7e-28 99.8 0.0 2.1 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KIK43569.1 - 0.0005 20.5 0.1 0.0019 18.6 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK43569.1 - 0.00065 20.1 0.0 0.002 18.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 KIK43569.1 - 0.0016 18.8 0.0 0.0037 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA_30 PF13604.6 KIK43569.1 - 0.0095 15.7 0.1 0.022 14.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK43569.1 - 0.022 15.0 0.1 0.18 12.0 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_6 PF12774.7 KIK43569.1 - 0.061 12.3 0.0 0.097 11.6 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 KIK43569.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABATE PF07336.11 KIK43569.1 - 0.58 10.8 3.4 3.6 8.3 0.8 2.6 2 0 0 2 2 2 0 Putative stress-induced transcription regulator Oxidored_molyb PF00174.19 KIK43570.1 - 6e-58 195.3 0.0 1.1e-57 194.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KIK43570.1 - 1e-48 164.8 0.2 1.7e-48 164.2 0.2 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.21 KIK43570.1 - 2.3e-27 95.8 0.0 1.9e-26 92.9 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KIK43570.1 - 4.2e-25 88.0 0.0 7.4e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KIK43570.1 - 1.2e-16 60.6 0.0 3.5e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KIK43570.1 - 8e-06 26.1 0.1 0.0003 21.0 0.0 2.5 3 0 0 3 3 3 1 Ferric reductase NAD binding domain WD40 PF00400.32 KIK43572.1 - 1.2e-40 136.7 26.5 2.9e-07 31.1 0.1 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43572.1 - 1.7e-12 47.4 3.2 0.027 14.8 0.1 5.8 2 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK43572.1 - 1.5e-06 27.4 0.1 0.013 14.5 0.0 3.8 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK43572.1 - 1.8e-06 28.0 0.0 0.34 10.8 0.0 3.3 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK43572.1 - 0.00035 20.4 0.0 7.9 6.6 0.0 4.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat TPR_2 PF07719.17 KIK43572.1 - 0.0016 18.4 0.0 67 4.0 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Nup160 PF11715.8 KIK43572.1 - 0.0057 15.4 0.9 0.3 9.7 0.1 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 DUF3856 PF12968.7 KIK43572.1 - 0.26 11.4 0.8 5.5 7.0 0.0 2.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_2 PF07719.17 KIK43573.1 - 3.8e-05 23.5 2.3 0.46 10.7 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK43573.1 - 0.00047 19.9 0.3 0.24 11.3 0.6 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK43573.1 - 0.01 16.1 8.4 0.79 10.1 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK43573.1 - 0.028 14.4 0.1 24 5.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK43573.1 - 0.21 11.9 7.3 1.6 9.1 0.4 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Methyltransf_25 PF13649.6 KIK43574.1 - 0.00071 20.2 0.1 0.008 16.9 0.0 2.2 1 1 0 2 2 2 1 Methyltransferase domain Sec62 PF03839.16 KIK43575.1 - 1.6e-51 174.9 5.3 5.4e-51 173.2 5.3 1.7 1 1 0 1 1 1 1 Translocation protein Sec62 Sperm_Ag_HE2 PF05324.13 KIK43575.1 - 4.6 7.8 6.0 19 5.8 0.0 3.1 3 0 0 3 3 3 0 Sperm antigen HE2 Ribosomal_L7Ae PF01248.26 KIK43576.1 - 2.1e-22 78.7 0.6 3.7e-22 77.9 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.12 KIK43576.1 - 0.2 10.7 0.4 0.29 10.1 0.4 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) 4HBT PF03061.22 KIK43577.1 - 9.3e-06 25.9 0.1 3e-05 24.3 0.0 2.0 2 1 0 2 2 2 1 Thioesterase superfamily UPF0203 PF05254.12 KIK43581.1 - 0.081 13.2 1.1 0.11 12.8 1.1 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) TEA PF01285.18 KIK43582.1 - 1.4e-19 69.9 0.0 2.9e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 TEA/ATTS domain Stn1 PF10451.9 KIK43583.1 - 3.1e-06 26.4 0.1 0.00053 19.0 0.2 2.2 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 KIK43583.1 - 0.0021 18.0 0.6 0.017 15.1 0.6 2.2 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain Ornatin PF02088.15 KIK43584.1 - 0.062 13.1 0.4 0.092 12.5 0.4 1.2 1 0 0 1 1 1 0 Ornatin TENA_THI-4 PF03070.16 KIK43587.1 - 0.00081 19.3 0.4 0.002 18.0 0.4 1.6 1 1 0 1 1 1 1 TENA/THI-4/PQQC family WD40 PF00400.32 KIK43588.1 - 4.5e-24 84.2 19.9 0.00016 22.4 0.2 11.4 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43588.1 - 4.6e-15 55.7 0.1 3.4e-05 24.0 0.0 5.4 4 3 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK43588.1 - 0.11 11.4 0.3 17 4.2 0.0 3.3 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CPSF_A PF03178.15 KIK43588.1 - 0.13 11.6 0.0 0.81 8.9 0.0 2.2 2 0 0 2 2 2 0 CPSF A subunit region GspH PF12019.8 KIK43588.1 - 0.43 11.0 4.7 9.3 6.7 0.0 3.8 4 0 0 4 4 4 0 Type II transport protein GspH Mad3_BUB1_I PF08311.12 KIK43589.1 - 1.1e-34 119.1 0.2 1.6e-34 118.5 0.2 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Cupin_1 PF00190.22 KIK43590.1 - 1.1e-41 142.0 0.3 1.1e-20 73.8 0.1 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KIK43590.1 - 5.2e-24 83.8 0.6 8.2e-12 44.7 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KIK43590.1 - 3.1e-11 42.8 0.0 1.2e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) 3-HAO PF06052.12 KIK43590.1 - 0.00017 21.2 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 2 3-hydroxyanthranilic acid dioxygenase Cupin_8 PF13621.6 KIK43590.1 - 0.00056 19.7 0.0 0.47 10.1 0.0 2.2 2 0 0 2 2 2 2 Cupin-like domain Cupin_4 PF08007.12 KIK43590.1 - 0.00075 19.1 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein AraC_binding PF02311.19 KIK43590.1 - 0.0024 17.8 0.3 0.17 11.8 0.1 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 KIK43590.1 - 0.0026 17.6 0.0 0.02 14.8 0.0 2.0 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase GPI PF06560.11 KIK43590.1 - 0.0095 15.2 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) ARD PF03079.14 KIK43590.1 - 0.0095 16.1 0.0 1.7 8.8 0.0 2.2 2 0 0 2 2 2 1 ARD/ARD' family DUF1971 PF09313.11 KIK43590.1 - 0.086 12.9 0.0 3.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1971) SVWC PF15430.6 KIK43591.1 - 0.13 12.6 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Single domain von Willebrand factor type C RRM_1 PF00076.22 KIK43593.1 - 5.1e-39 131.9 0.0 4.3e-18 64.9 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KIK43593.1 - 7.2e-06 26.1 0.4 0.00015 21.8 0.1 2.7 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.6 KIK43593.1 - 0.063 13.3 0.1 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 KIK43593.1 - 0.12 12.4 0.4 9.5 6.4 0.0 2.9 3 0 0 3 3 3 0 Limkain b1 RRM_5 PF13893.6 KIK43593.1 - 0.14 11.8 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 KIK43595.1 - 2.4e-29 102.4 32.7 2.4e-29 102.4 32.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Mitoc_mL59 PF18126.1 KIK43596.1 - 1.4e-40 138.6 6.0 2.3e-40 137.9 6.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Rad52_Rad22 PF04098.15 KIK43598.1 - 2e-56 190.2 0.0 2.8e-56 189.7 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein MraY_sig1 PF10555.9 KIK43598.1 - 0.45 10.1 2.0 0.94 9.1 2.0 1.5 1 0 0 1 1 1 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 Sterol_MT_C PF08498.10 KIK43601.1 - 7.6e-29 99.8 0.2 1.2e-28 99.2 0.2 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.6 KIK43601.1 - 2.1e-18 66.5 0.0 3e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK43601.1 - 8.2e-18 64.8 0.0 1.4e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK43601.1 - 2.3e-16 60.3 0.0 4e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KIK43601.1 - 1.1e-14 54.4 0.0 1.5e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KIK43601.1 - 1.9e-11 44.6 0.0 4.6e-11 43.3 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK43601.1 - 4.8e-10 39.5 0.0 6.7e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK43601.1 - 1e-07 31.6 0.0 1.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KIK43601.1 - 4.6e-05 23.3 0.0 7.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.17 KIK43601.1 - 0.00011 21.5 0.0 0.00018 20.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase MetW PF07021.12 KIK43601.1 - 0.0025 17.4 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_15 PF09445.10 KIK43601.1 - 0.0031 17.1 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 KIK43601.1 - 0.0059 16.3 0.0 0.0092 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.14 KIK43601.1 - 0.0071 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KIK43601.1 - 0.0083 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_32 PF13679.6 KIK43601.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KIK43601.1 - 0.033 13.6 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.6 KIK43601.1 - 0.037 15.1 0.0 0.11 13.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KIK43601.1 - 0.14 11.6 0.0 0.53 9.7 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase PH_9 PF15410.6 KIK43604.1 - 0.0002 21.7 0.0 0.00025 21.4 0.0 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KIK43604.1 - 0.016 15.7 0.0 0.017 15.6 0.0 1.1 1 0 0 1 1 1 0 PH domain Metallophos PF00149.28 KIK43605.1 - 3.3e-40 138.8 0.1 4.3e-40 138.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KIK43605.1 - 9.9e-22 77.1 0.5 2.1e-21 76.1 0.2 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Sugar_tr PF00083.24 KIK43606.1 - 7.3e-88 295.4 22.9 8.3e-88 295.2 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK43606.1 - 1.6e-24 86.5 32.4 2.9e-21 75.8 21.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG11 PF10377.9 KIK43607.1 - 2.8e-31 108.3 0.8 1.9e-30 105.5 0.0 2.7 2 0 0 2 2 2 1 Autophagy-related protein 11 DUF1769 PF08588.10 KIK43608.1 - 1.5e-22 79.6 0.2 2.9e-22 78.6 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) US6 PF17616.2 KIK43610.1 - 0.057 13.4 0.1 0.062 13.2 0.1 1.1 1 0 0 1 1 1 0 Viral unique short region 6 Omega-toxin PF06357.11 KIK43614.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Omega-atracotoxin F-box PF00646.33 KIK43615.1 - 0.00044 20.1 0.1 0.0019 18.0 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIK43615.1 - 0.037 13.9 0.0 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 F-box-like DUF4743 PF15916.5 KIK43616.1 - 3.9e-07 30.1 0.0 0.00056 19.9 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4743) NUDIX PF00293.28 KIK43616.1 - 8.7e-06 25.8 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Sds3 PF08598.11 KIK43618.1 - 4e-25 89.1 1.5 4.8e-25 88.8 1.5 1.0 1 0 0 1 1 1 1 Sds3-like Plus-3 PF03126.18 KIK43619.1 - 3.7e-36 124.0 0.0 3.9e-35 120.7 0.0 2.4 2 0 0 2 2 2 1 Plus-3 domain Vps26 PF03643.15 KIK43620.1 - 4.2e-129 429.4 1.3 4.9e-129 429.2 1.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KIK43620.1 - 0.0041 17.2 0.3 0.56 10.2 0.1 3.0 2 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KIK43620.1 - 0.06 13.8 0.0 4.2 7.8 0.0 2.6 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain DUF3397 PF11877.8 KIK43621.1 - 0.086 13.1 2.5 0.17 12.1 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3397) Sof1 PF04158.14 KIK43622.1 - 3.1e-30 104.3 9.5 9.3e-30 102.8 9.5 1.9 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KIK43622.1 - 2.2e-22 78.9 13.2 1.1e-07 32.4 0.9 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43622.1 - 7.5e-06 26.2 0.2 0.44 10.9 0.0 4.1 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 KIK43623.1 - 4.3e-08 32.9 0.2 1.4e-07 31.3 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK43623.1 - 0.041 13.8 0.1 19 5.3 0.0 3.2 2 0 0 2 2 2 0 F-box domain NAD_binding_6 PF08030.12 KIK43625.1 - 8.6e-37 126.7 0.0 1.5e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KIK43625.1 - 2.6e-23 82.2 0.0 5.2e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KIK43625.1 - 1.8e-20 73.3 8.4 1.8e-20 73.3 8.4 2.3 1 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 KIK43625.1 - 0.19 12.1 0.0 0.37 11.2 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KIK43625.1 - 0.2 12.3 0.0 1.1 9.9 0.0 2.2 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain His_Phos_2 PF00328.22 KIK43629.1 - 0.00095 18.6 0.0 1.1 8.5 0.0 2.5 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) VIT1 PF01988.19 KIK43630.1 - 6.9e-62 209.1 2.7 8.5e-62 208.8 2.7 1.1 1 0 0 1 1 1 1 VIT family SMRP1 PF15181.6 KIK43630.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Spermatid-specific manchette-related protein 1 DUF2013 PF09431.10 KIK43631.1 - 1.7e-54 183.8 1.7 3.3e-54 182.8 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) DEAD PF00270.29 KIK43632.1 - 2.9e-46 157.4 0.0 5.4e-46 156.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK43632.1 - 2.2e-23 82.7 0.0 1.4e-22 80.1 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KIK43632.1 - 1.6e-20 73.1 0.0 3.7e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KIK43632.1 - 3.4e-06 27.2 0.0 1.1e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NINJA_B PF16136.5 KIK43632.1 - 0.63 10.4 3.3 3.7 8.0 0.5 2.7 2 0 0 2 2 2 0 Putative nuclear localisation signal DIOX_N PF14226.6 KIK43633.1 - 4e-17 63.0 0.0 1.1e-16 61.7 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK43633.1 - 3.4e-15 56.4 0.0 6.8e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Potex_coat PF06184.11 KIK43633.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Potexvirus coat protein DIOX_N PF14226.6 KIK43634.1 - 1.8e-13 51.3 0.0 4.1e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK43634.1 - 1.9e-13 50.8 0.0 3.2e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CLN3 PF02487.17 KIK43636.1 - 1.1e-133 446.2 3.4 1.3e-133 445.9 3.4 1.0 1 0 0 1 1 1 1 CLN3 protein Fungal_trans PF04082.18 KIK43637.1 - 6.2e-18 64.8 0.0 1.5e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK43637.1 - 0.00013 22.0 13.9 0.00027 21.0 13.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PDR_CDR PF06422.12 KIK43638.1 - 0.13 12.2 0.1 0.15 12.0 0.1 1.1 1 0 0 1 1 1 0 CDR ABC transporter TB2_DP1_HVA22 PF03134.19 KIK43640.1 - 1.3e-27 95.5 2.6 2.2e-27 94.8 2.6 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family BAH PF01426.18 KIK43641.1 - 0.00025 20.9 0.1 0.00047 20.0 0.1 1.4 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 KIK43641.1 - 0.031 14.2 10.2 0.14 12.0 2.7 3.6 4 0 0 4 4 4 0 PHD-finger Prok-RING_1 PF14446.6 KIK43641.1 - 3.9 7.5 11.5 1.1 9.3 4.5 2.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Velvet PF11754.8 KIK43643.1 - 6e-39 134.5 0.0 8e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Velvet factor Glucan_synthase PF02364.15 KIK43645.1 - 0 1315.4 0.0 0 1315.0 0.0 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KIK43645.1 - 1.2e-42 145.2 0.1 3.6e-42 143.8 0.1 1.8 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 E1-E2_ATPase PF00122.20 KIK43646.1 - 0.032 13.8 0.4 0.066 12.7 0.1 1.7 2 0 0 2 2 2 0 E1-E2 ATPase Orf78 PF06024.12 KIK43646.1 - 0.13 12.6 0.2 0.38 11.1 0.1 1.9 2 0 0 2 2 2 0 Orf78 (ac78) DUF2207 PF09972.9 KIK43646.1 - 0.37 9.5 1.4 0.45 9.2 0.2 1.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF3328 PF11807.8 KIK43646.1 - 2.9 7.6 6.5 1.7 8.4 0.4 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF3328) PNP_UDP_1 PF01048.20 KIK43647.1 - 9.9e-34 116.6 0.1 1.4e-33 116.1 0.1 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Iso_dh PF00180.20 KIK43648.1 - 6.2e-73 245.9 0.0 7.7e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF520 PF04461.13 KIK43648.1 - 0.066 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF520) DHFR_2 PF06442.11 KIK43648.1 - 0.082 12.8 0.0 10 6.0 0.0 2.5 2 0 0 2 2 2 0 R67 dihydrofolate reductase DIOX_N PF14226.6 KIK43650.1 - 1.1e-09 39.1 0.0 1.3e-09 38.9 0.0 1.1 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal ANAPC4_WD40 PF12894.7 KIK43654.1 - 8.6e-12 45.2 1.3 0.006 16.9 0.2 4.6 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK43654.1 - 4.8e-07 30.4 16.2 9.2e-05 23.1 1.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.11 KIK43654.1 - 6.3e-06 26.2 0.0 0.22 11.4 0.0 3.4 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A MDM10 PF12519.8 KIK43654.1 - 0.28 10.0 4.3 6.2 5.6 0.3 2.8 4 0 0 4 4 4 0 Mitochondrial distribution and morphology protein 10 FixQ PF05545.11 KIK43655.1 - 0.016 15.2 1.9 0.023 14.6 1.9 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF3592 PF12158.8 KIK43655.1 - 0.02 15.0 0.0 0.023 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) Zn_clus PF00172.18 KIK43660.1 - 4.7e-10 39.4 5.8 6.2e-10 39.0 5.8 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 KIK43660.1 - 0.05 13.9 4.3 0.08 13.3 1.7 2.0 2 0 0 2 2 2 0 Opy2 protein 2OG-FeII_Oxy_2 PF13532.6 KIK43661.1 - 3.6e-14 53.4 0.0 2.4e-13 50.7 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KIK43661.1 - 0.00036 21.0 0.6 0.0062 17.0 0.2 2.4 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily EF1G PF00647.19 KIK43662.1 - 1.1e-43 147.6 0.1 1.9e-43 146.9 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KIK43662.1 - 5e-10 39.5 0.5 1.2e-09 38.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KIK43662.1 - 3.7e-08 33.6 0.0 9.4e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK43662.1 - 1.5e-07 31.3 0.1 4.2e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK43662.1 - 2.9e-06 27.4 0.0 2.8e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIK43662.1 - 0.00023 21.5 0.0 0.00053 20.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK43662.1 - 0.15 12.3 0.0 0.45 10.9 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain OAD_gamma PF04277.13 KIK43662.1 - 0.89 10.2 4.1 1.6 9.4 4.1 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain ORC2 PF04084.14 KIK43663.1 - 3.4e-79 266.2 0.0 4.1e-79 265.9 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 ERG4_ERG24 PF01222.17 KIK43664.1 - 4.9e-142 473.7 3.2 5.6e-142 473.5 3.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 KIK43664.1 - 1.1e-05 25.7 0.4 9.8e-05 22.7 0.0 2.6 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 KIK43664.1 - 1.3e-05 24.9 0.1 1.3e-05 24.9 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KIK43664.1 - 0.0011 19.3 0.0 0.0037 17.6 0.0 1.8 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF5117 PF17148.4 KIK43668.1 - 0.072 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5117) HET PF06985.11 KIK43670.1 - 0.0012 19.2 0.1 0.0035 17.7 0.1 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 KIK43671.1 - 1.4e-33 116.4 0.0 2.1e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK43671.1 - 1.9e-29 102.8 0.0 2.6e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK43671.1 - 4.6e-05 22.9 0.0 7.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF5423 PF17461.2 KIK43672.1 - 0.13 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) BP28CT PF08146.12 KIK43673.1 - 4.4e-27 94.9 0.0 3.6e-26 91.9 0.0 2.6 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KIK43673.1 - 9.3e-15 55.0 3.7 1.2e-13 51.5 1.1 4.4 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 Polyketide_cyc2 PF10604.9 KIK43674.1 - 8.6e-08 32.6 1.1 2.2e-07 31.2 1.1 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KIK43674.1 - 0.00025 21.2 1.4 0.00048 20.3 1.4 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport EXS PF03124.14 KIK43674.1 - 0.047 13.0 0.1 0.047 13.0 0.1 1.2 1 0 0 1 1 1 0 EXS family ESCRT-II PF05871.12 KIK43675.1 - 0.032 14.5 0.1 0.061 13.6 0.1 1.4 1 0 0 1 1 1 0 ESCRT-II complex subunit PARM PF17061.5 KIK43675.1 - 0.14 12.3 12.2 0.15 12.1 12.2 1.1 1 0 0 1 1 1 0 PARM Miga PF10265.9 KIK43675.1 - 2.7 6.8 6.5 3.2 6.6 6.5 1.1 1 0 0 1 1 1 0 Mitoguardin MAGI_u1 PF16663.5 KIK43675.1 - 7 6.8 12.5 0.39 10.8 3.1 2.5 2 1 0 2 2 2 0 Unstructured region on MAGI Rep_N PF08724.10 KIK43676.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Rep protein catalytic domain like RNA_GG_bind PF10258.9 KIK43676.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 PHAX RNA-binding domain Membr_traf_MHD PF10540.9 KIK43679.1 - 1.6e-25 90.1 0.5 1.6e-22 80.3 0.5 2.9 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KIK43679.1 - 5.1e-09 36.4 0.0 1.2e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain HSP70 PF00012.20 KIK43680.1 - 5.5e-81 272.6 3.1 5.5e-81 272.6 3.1 2.5 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KIK43680.1 - 0.00012 21.0 0.1 0.00036 19.5 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KIK43680.1 - 0.0073 16.1 0.1 0.67 9.7 0.1 2.9 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain CHAT PF12770.7 KIK43681.1 - 1.2e-40 139.7 0.1 3.9e-40 138.1 0.0 1.8 2 0 0 2 2 2 1 CHAT domain TPR_10 PF13374.6 KIK43681.1 - 1.6e-30 104.1 19.8 0.00012 21.8 0.0 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.6 KIK43681.1 - 9.8e-15 54.6 17.1 0.28 11.5 0.0 10.6 7 3 5 12 12 12 4 Tetratricopeptide repeat TPR_7 PF13176.6 KIK43681.1 - 2.6e-07 30.2 2.7 17 5.7 0.0 9.0 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK43681.1 - 0.00079 19.1 1.2 19 5.1 0.0 6.3 8 0 0 8 8 8 0 TPR repeat TPR_17 PF13431.6 KIK43681.1 - 0.0012 19.1 0.0 4.4 7.9 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK43681.1 - 0.0035 17.4 0.1 68 4.1 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat Herpes_UL31 PF02718.14 KIK43681.1 - 0.0074 15.3 0.0 0.17 10.8 0.1 2.2 2 0 0 2 2 2 1 Herpesvirus UL31-like protein TPR_1 PF00515.28 KIK43681.1 - 0.032 14.1 17.1 25 4.9 0.0 8.7 10 0 0 10 10 9 0 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 KIK43681.1 - 0.2 11.7 1.9 41 4.4 0.0 4.9 6 0 0 6 6 6 0 Exonuclease VII small subunit TPR_2 PF07719.17 KIK43681.1 - 1.7 9.0 12.5 17 5.8 0.0 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat T3SS_ATPase_C PF18269.1 KIK43681.1 - 3.5 7.5 8.9 50 3.9 0.0 5.4 7 0 0 7 7 7 0 T3SS EscN ATPase C-terminal domain TPR_14 PF13428.6 KIK43681.1 - 8.9 7.4 29.1 6.5 7.8 0.1 10.2 11 1 1 12 12 11 0 Tetratricopeptide repeat Corona_M PF01635.18 KIK43683.1 - 0.053 12.8 5.4 0.095 12.0 5.4 1.4 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein DUF3784 PF12650.7 KIK43683.1 - 8.1 6.7 13.8 6.5 7.0 6.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) CAP_N PF01213.19 KIK43684.1 - 7 6.0 5.5 8.5 5.8 5.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MFS_1 PF07690.16 KIK43685.1 - 1.5e-24 86.6 24.8 1.5e-24 86.6 24.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily WD40 PF00400.32 KIK43686.1 - 3.2e-37 125.9 16.8 8.7e-08 32.7 2.8 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43686.1 - 1.2e-18 67.2 1.5 0.0016 18.7 0.0 5.8 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK43686.1 - 8.4e-08 31.5 0.1 0.11 11.4 0.0 4.4 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK43686.1 - 0.00033 20.1 0.7 2.7 7.3 0.0 4.0 2 2 2 4 4 4 3 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK43686.1 - 0.0016 17.2 0.5 0.78 8.3 0.0 4.2 5 0 0 5 5 5 1 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KIK43686.1 - 0.0076 15.2 1.6 0.14 11.1 0.0 2.3 2 0 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain PD40 PF07676.12 KIK43686.1 - 0.0097 15.8 0.2 1.5 8.9 0.0 3.6 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat RasGEF PF00617.19 KIK43687.1 - 3.4e-30 105.6 0.0 1.6e-29 103.3 0.0 2.0 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KIK43687.1 - 1.6e-08 34.7 0.7 4.9e-08 33.2 0.7 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif ASF1_hist_chap PF04729.13 KIK43688.1 - 4.1e-62 208.7 0.0 4.7e-62 208.5 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone UCH PF00443.29 KIK43689.1 - 2.1e-39 135.6 0.0 2.9e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIK43689.1 - 3.9e-11 43.1 0.2 5.1e-06 26.3 0.1 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KIK43689.1 - 3e-05 23.7 0.0 6.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Bap31 PF05529.12 KIK43690.1 - 2.8e-46 156.7 3.8 4.1e-46 156.2 3.8 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KIK43690.1 - 3.2e-11 43.0 7.5 3.2e-11 43.0 7.5 1.8 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain TarH PF02203.15 KIK43690.1 - 0.34 10.8 5.1 0.31 10.9 3.1 1.8 2 0 0 2 2 2 0 Tar ligand binding domain homologue zf-primase PF09329.11 KIK43691.1 - 2.2e-16 59.4 1.4 4.7e-16 58.3 1.4 1.6 1 0 0 1 1 1 1 Primase zinc finger DUF1556 PF07590.11 KIK43691.1 - 4.6 7.6 7.9 9.4 6.6 1.6 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1556) DUF4238 PF14022.6 KIK43693.1 - 0.24 10.9 0.0 0.25 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) GMC_oxred_N PF00732.19 KIK43694.1 - 1.1e-56 192.4 0.0 1.8e-56 191.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK43694.1 - 1.6e-28 100.0 0.0 3.1e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KIK43694.1 - 0.0011 18.1 0.0 0.0021 17.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KIK43694.1 - 0.018 14.1 0.1 0.034 13.2 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 KIK43694.1 - 0.15 11.2 0.1 1 8.5 0.0 2.1 2 0 0 2 2 2 0 Thi4 family AAA PF00004.29 KIK43696.1 - 0.00022 21.6 0.0 0.00052 20.4 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIK43696.1 - 0.00024 21.1 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIK43696.1 - 0.002 18.5 0.0 0.011 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KIK43696.1 - 0.0049 16.1 0.0 0.0082 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 KIK43696.1 - 0.062 13.1 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KIK43696.1 - 0.091 13.3 0.0 0.25 11.9 0.0 1.9 2 1 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 KIK43696.1 - 0.093 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 KIK43696.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MCM PF00493.23 KIK43696.1 - 0.18 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 KIK43696.1 - 0.21 11.1 0.0 0.39 10.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region GMC_oxred_N PF00732.19 KIK43697.1 - 1.1e-57 195.7 0.0 1.5e-57 195.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK43697.1 - 3.1e-28 99.1 0.0 8.7e-28 97.7 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK43697.1 - 0.0024 17.0 0.2 0.047 12.7 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein pKID PF02173.17 KIK43697.1 - 0.034 13.6 0.4 0.064 12.7 0.4 1.4 1 0 0 1 1 1 0 pKID domain FAD_binding_2 PF00890.24 KIK43697.1 - 0.093 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain RINGv PF12906.7 KIK43698.1 - 2.8e-06 27.4 8.6 5.4e-06 26.4 8.6 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KIK43698.1 - 0.0057 17.0 8.2 0.0057 17.0 8.2 1.8 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 KIK43698.1 - 0.013 15.7 4.6 0.024 14.8 4.6 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KIK43698.1 - 1.9 8.2 10.2 0.2 11.3 1.9 2.7 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KIK43698.1 - 8 6.8 8.3 23 5.4 8.3 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain RRM_1 PF00076.22 KIK43699.1 - 7.1e-14 51.4 0.0 9.5e-14 51.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KIK43699.1 - 0.00073 19.5 0.0 0.001 19.0 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif PPR_2 PF13041.6 KIK43700.1 - 3.2e-13 49.6 0.0 0.00053 20.1 0.0 5.1 5 0 0 5 5 5 3 PPR repeat family PPR_long PF17177.4 KIK43700.1 - 5.8e-07 29.1 0.1 0.048 13.0 0.1 4.0 3 1 1 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KIK43700.1 - 0.0015 18.7 0.0 0.078 13.3 0.0 3.6 3 0 0 3 3 3 1 PPR repeat PPR_1 PF12854.7 KIK43700.1 - 0.053 13.2 0.0 0.82 9.4 0.0 3.0 4 0 0 4 4 4 0 PPR repeat DUF4074 PF13293.6 KIK43701.1 - 0.024 14.9 0.1 0.031 14.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4074) MFS_1 PF07690.16 KIK43703.1 - 7.7e-28 97.4 23.2 2.5e-27 95.7 24.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KIK43703.1 - 0.00017 21.0 17.6 0.00074 18.9 3.9 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB PepSY_2 PF13670.6 KIK43703.1 - 0.047 13.7 0.8 0.047 13.7 0.8 1.8 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain InaF-motif PF15018.6 KIK43703.1 - 0.2 11.5 2.6 0.65 9.9 0.7 2.6 2 0 0 2 2 2 0 TRP-interacting helix XhlA PF10779.9 KIK43703.1 - 2 8.7 4.9 22 5.3 0.1 2.7 2 0 0 2 2 2 0 Haemolysin XhlA DUF2235 PF09994.9 KIK43706.1 - 2.7e-73 246.8 0.0 3.8e-73 246.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Adaptin_N PF01602.20 KIK43706.1 - 0.00047 18.8 1.8 0.00083 18.0 0.4 1.8 1 1 0 1 1 1 1 Adaptin N terminal region RTP1_C1 PF10363.9 KIK43706.1 - 0.0096 16.1 0.5 0.081 13.1 0.0 2.6 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 KIK43706.1 - 0.023 15.1 0.1 0.29 11.5 0.1 2.5 1 1 1 2 2 2 0 HEAT repeats Cnd1 PF12717.7 KIK43706.1 - 0.061 13.4 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 DCB PF16213.5 KIK43706.1 - 0.061 13.0 0.6 0.11 12.1 0.6 1.4 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 DUF3361 PF11841.8 KIK43706.1 - 0.14 12.1 0.3 1.2 9.1 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3361) HEAT PF02985.22 KIK43706.1 - 0.18 12.2 3.7 1.5 9.3 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat Methyltransf_10 PF05971.12 KIK43707.1 - 4e-73 246.4 0.0 5e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KIK43707.1 - 1.4e-07 31.2 0.0 2.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KIK43707.1 - 2.8e-06 26.9 0.0 4e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KIK43707.1 - 1.2e-05 25.2 0.0 1.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 KIK43707.1 - 0.00013 21.8 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 KIK43707.1 - 0.00016 22.3 0.0 0.00044 20.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK43707.1 - 0.0011 19.6 0.0 0.0023 18.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KIK43707.1 - 0.0041 17.1 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK43707.1 - 0.0091 16.7 0.0 0.017 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK43707.1 - 0.088 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PEMT PF04191.13 KIK43712.1 - 1.4e-32 112.3 2.4 1.4e-32 112.3 2.4 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase adh_short_C2 PF13561.6 KIK43713.1 - 1.1e-36 126.5 0.5 1.4e-36 126.3 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK43713.1 - 3.1e-31 108.4 0.5 4.1e-31 108.0 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK43713.1 - 8e-08 32.4 1.2 2e-07 31.1 1.2 1.6 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KIK43713.1 - 0.0021 17.5 0.4 0.16 11.3 0.0 2.2 1 1 1 2 2 2 2 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KIK43713.1 - 0.081 12.4 0.1 0.11 12.0 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family UQ_con PF00179.26 KIK43714.1 - 1.3e-50 170.7 0.0 1.5e-50 170.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIK43714.1 - 0.00069 19.3 0.0 0.00093 18.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B F-box PF00646.33 KIK43716.1 - 2.7e-05 23.9 0.2 9.5e-05 22.2 0.1 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIK43716.1 - 0.00011 22.0 0.1 0.00026 20.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like FliD_N PF02465.18 KIK43717.1 - 0.13 13.0 2.8 0.089 13.5 1.6 1.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus WD40 PF00400.32 KIK43720.1 - 6.2e-21 74.3 18.7 1.5e-08 35.1 0.7 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43720.1 - 4.5e-16 58.9 0.3 0.00017 21.8 0.0 5.5 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK43720.1 - 1.3e-07 31.4 4.4 1.2 9.2 0.0 6.3 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KIK43720.1 - 7e-07 29.3 0.0 0.0032 17.4 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.11 KIK43720.1 - 0.017 14.2 0.7 1.5 7.8 0.1 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF1513) Ge1_WD40 PF16529.5 KIK43720.1 - 0.022 13.7 0.1 5.9 5.7 0.0 3.4 2 2 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 KIK43720.1 - 0.031 14.2 0.1 59 3.9 0.0 4.2 4 0 0 4 4 4 0 PQQ enzyme repeat Nup160 PF11715.8 KIK43720.1 - 0.054 12.1 0.2 29 3.1 0.0 3.5 4 1 0 4 4 4 0 Nucleoporin Nup120/160 WD40 PF00400.32 KIK43721.1 - 1.8e-25 88.7 15.4 3.7e-07 30.7 0.1 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43721.1 - 2.9e-18 66.0 0.3 8.1e-05 22.9 0.0 4.6 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK43721.1 - 1.4e-07 30.8 0.0 0.0004 19.4 0.0 2.9 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK43721.1 - 1.2e-06 28.6 0.4 0.0054 16.6 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK43721.1 - 4.3e-05 22.4 2.0 1.7 7.2 0.0 4.6 3 2 1 5 5 5 2 Nucleoporin Nup120/160 PD40 PF07676.12 KIK43721.1 - 0.0011 18.9 0.0 20 5.3 0.0 4.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK43721.1 - 0.004 16.5 0.3 0.73 9.1 0.0 3.3 2 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal PQQ PF01011.21 KIK43721.1 - 0.068 13.1 5.6 24 5.1 0.0 5.2 6 0 0 6 6 6 0 PQQ enzyme repeat PQQ_3 PF13570.6 KIK43721.1 - 0.13 12.8 1.9 1.7 9.2 0.0 3.4 2 1 1 3 3 3 0 PQQ-like domain CRT10 PF08728.10 KIK43721.1 - 0.13 10.4 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 CRT10 WD40 PF00400.32 KIK43722.1 - 1e-23 83.1 20.5 3.7e-07 30.7 0.9 7.5 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43722.1 - 1.4e-13 50.9 0.6 0.00079 19.7 0.0 5.6 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK43722.1 - 2.6e-06 27.5 0.0 0.0043 17.0 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK43722.1 - 2.1e-05 23.7 0.0 0.091 11.7 0.0 3.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 KIK43722.1 - 0.0015 19.0 0.0 17 6.1 0.0 4.1 4 1 0 4 4 4 2 PQQ-like domain PD40 PF07676.12 KIK43722.1 - 0.0021 17.9 0.2 22 5.1 0.0 5.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK43722.1 - 0.0085 14.8 2.3 5.9 5.4 0.1 3.9 4 2 1 6 6 6 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KIK43722.1 - 0.075 12.6 0.2 1.4 8.4 0.0 2.7 1 1 0 2 2 2 0 PQQ-like domain Bunya_RdRp PF04196.12 KIK43723.1 - 0.47 8.8 0.9 0.6 8.4 0.9 1.1 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase TALPID3 PF15324.6 KIK43723.1 - 1.6 6.3 6.8 1.8 6.1 6.8 1.0 1 0 0 1 1 1 0 Hedgehog signalling target SNase PF00565.17 KIK43724.1 - 1.8e-16 60.6 0.0 8.2e-16 58.4 0.0 2.0 2 0 0 2 2 2 1 Staphylococcal nuclease homologue TilS PF09179.11 KIK43727.1 - 0.072 13.6 0.1 3 8.4 0.0 2.6 2 1 1 3 3 3 0 TilS substrate binding domain Lipase_GDSL_2 PF13472.6 KIK43727.1 - 0.12 12.7 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family WD40 PF00400.32 KIK43728.1 - 1.8e-33 114.0 9.3 1.4e-05 25.8 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43728.1 - 1.4e-16 60.6 0.5 0.026 14.8 0.0 5.3 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK43728.1 - 1.5e-05 25.0 0.0 0.075 12.9 0.0 2.7 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK43728.1 - 2.2e-05 23.6 0.2 0.49 9.3 0.0 3.6 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Robl_LC7 PF03259.17 KIK43728.1 - 0.012 15.4 0.1 0.033 14.0 0.1 1.8 1 0 0 1 1 1 0 Roadblock/LC7 domain PD40 PF07676.12 KIK43728.1 - 0.024 14.6 0.2 2.1 8.4 0.0 4.1 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 KIK43728.1 - 0.099 11.7 0.2 14 4.6 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) TPR_2 PF07719.17 KIK43728.1 - 0.34 11.1 3.3 7.9 6.9 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-MYND PF01753.18 KIK43730.1 - 0.0069 16.5 24.5 1.3 9.2 2.1 4.4 4 0 0 4 4 4 4 MYND finger RPAP2_Rtr1 PF04181.13 KIK43730.1 - 0.06 13.7 16.5 9.1 6.7 0.5 4.4 3 1 0 3 3 3 0 Rtr1/RPAP2 family PLATZ PF04640.14 KIK43730.1 - 0.2 12.3 15.0 1.7 9.3 1.9 3.5 3 1 0 3 3 3 0 PLATZ transcription factor DIOX_N PF14226.6 KIK43733.1 - 8.1e-25 87.9 0.0 1.3e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK43733.1 - 8.4e-18 64.7 0.0 1.4e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2461 PF09365.10 KIK43734.1 - 8.5e-62 208.8 0.0 6e-38 130.9 0.1 2.1 2 0 0 2 2 2 2 Conserved hypothetical protein (DUF2461) ORC6 PF05460.13 KIK43734.1 - 0.15 11.3 2.4 0.3 10.3 2.1 1.7 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) SCIMP PF15050.6 KIK43734.1 - 0.22 12.0 3.2 0.86 10.1 0.0 2.3 2 0 0 2 2 2 0 SCIMP protein Consortin_C PF15281.6 KIK43734.1 - 0.41 10.6 2.1 0.93 9.5 2.1 1.5 1 0 0 1 1 1 0 Consortin C-terminus Nucleo_P87 PF07267.11 KIK43734.1 - 3.4 6.4 6.0 4.8 5.9 6.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RicinB_lectin_2 PF14200.6 KIK43736.1 - 7.8e-13 49.0 4.3 1.7e-08 35.1 1.6 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIK43736.1 - 4.4e-07 30.2 1.5 0.0053 17.0 0.5 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain tRNA-synt_1d PF00750.19 KIK43737.1 - 1.6e-23 83.3 0.1 5.6e-23 81.4 0.1 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (R) MDMPI_C PF07398.11 KIK43738.1 - 0.29 12.0 2.1 1.2 10.1 0.1 2.1 2 0 0 2 2 2 0 MDMPI C-terminal domain SDA1 PF05285.12 KIK43738.1 - 0.31 10.4 6.4 0.39 10.1 6.4 1.0 1 0 0 1 1 1 0 SDA1 WD40 PF00400.32 KIK43741.1 - 6.6e-32 109.0 11.9 1.3e-05 25.9 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43741.1 - 2.5e-11 43.7 0.6 0.014 15.7 0.0 4.9 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK43741.1 - 1.7e-05 23.7 4.4 0.15 10.6 0.0 3.1 3 0 0 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK43741.1 - 0.0012 17.9 0.6 0.095 11.6 0.0 3.5 1 1 4 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK43741.1 - 0.0033 16.8 0.2 0.032 13.6 0.1 2.5 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 KIK43741.1 - 0.014 14.1 0.2 3.3 6.3 0.0 2.9 1 1 1 3 3 3 0 Nup133 N terminal like HPS3_N PF14761.6 KIK43741.1 - 0.086 12.4 0.0 19 4.7 0.0 3.0 2 1 2 4 4 4 0 Hermansky-Pudlak syndrome 3 TPR_2 PF07719.17 KIK43742.1 - 9.4e-07 28.5 0.6 1.2 9.4 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK43742.1 - 0.00016 21.4 0.4 3.2 7.7 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIK43742.1 - 0.01 16.4 0.1 0.46 11.2 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK43742.1 - 0.011 16.4 0.6 11 6.8 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK43742.1 - 0.012 16.3 0.2 3.4 8.7 0.0 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat ABC_membrane_2 PF06472.15 KIK43742.1 - 0.069 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 WD40 PF00400.32 KIK43743.1 - 5.6e-07 30.2 1.1 0.00014 22.6 0.1 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.32 KIK43744.1 - 2.5e-05 24.9 0.1 0.001 19.8 0.0 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43744.1 - 0.051 13.9 0.0 1.5 9.2 0.0 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Exo_endo_phos PF03372.23 KIK43746.1 - 5.9e-11 42.3 0.2 1.7e-10 40.9 0.2 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 KIK43746.1 - 1.5e-05 25.0 0.4 3.3e-05 23.9 0.4 1.6 1 0 0 1 1 1 1 GRF zinc finger Spuma_A9PTase PF03539.14 KIK43746.1 - 0.018 15.1 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) Exo_endo_phos_2 PF14529.6 KIK43746.1 - 0.094 12.6 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase RHINO PF15319.6 KIK43746.1 - 0.82 9.7 6.6 1.4 8.9 6.6 1.3 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein Kinesin PF00225.23 KIK43747.1 - 6.8e-93 311.2 0.2 6.8e-93 311.2 0.2 1.7 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KIK43747.1 - 6.7e-58 194.9 0.0 1.5e-57 193.7 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding HIP1_clath_bdg PF16515.5 KIK43747.1 - 0.015 15.9 9.7 0.015 15.9 9.7 3.2 2 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 AJAP1_PANP_C PF15298.6 KIK43747.1 - 0.078 13.2 0.3 0.25 11.6 0.3 1.8 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF3584 PF12128.8 KIK43747.1 - 0.12 9.9 23.8 0.16 9.5 23.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) KASH_CCD PF14662.6 KIK43747.1 - 3 7.7 27.9 1.5 8.6 14.3 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DAP3 PF10236.9 KIK43748.1 - 2e-62 211.2 0.0 2.7e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 KIK43748.1 - 1.1e-08 35.6 0.0 1.7e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIK43748.1 - 6e-05 23.1 0.0 0.00013 22.0 0.0 1.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KIK43748.1 - 0.0029 17.4 0.0 0.0048 16.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 KIK43748.1 - 0.0055 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KIK43748.1 - 0.0075 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_25 PF13481.6 KIK43748.1 - 0.032 13.8 0.0 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KIK43748.1 - 0.13 12.5 0.0 0.85 9.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.7 KIK43748.1 - 0.14 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ThiJ_like PF17124.5 KIK43749.1 - 0.19 11.4 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 ThiJ/PfpI family-like DUF3902 PF13042.6 KIK43750.1 - 0.0076 15.8 1.7 0.01 15.4 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3902) Asp PF00026.23 KIK43751.1 - 3.2e-18 66.2 0.0 5.1e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Ribosomal_L35Ae PF01247.18 KIK43753.1 - 8.7e-46 154.0 0.6 9.7e-46 153.9 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KIK43753.1 - 0.00073 19.7 0.0 0.86 9.9 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain ArgJ PF01960.18 KIK43754.1 - 3.5e-145 483.4 0.0 4e-145 483.3 0.0 1.0 1 0 0 1 1 1 1 ArgJ family Amidase PF01425.21 KIK43756.1 - 1.7e-71 241.6 0.0 6.4e-71 239.6 0.0 1.7 1 1 0 1 1 1 1 Amidase GATA PF00320.27 KIK43757.1 - 5.6e-08 32.3 7.9 9.2e-08 31.6 7.9 1.4 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.18 KIK43757.1 - 0.17 12.0 1.0 0.3 11.1 1.0 1.3 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf DUF2517 PF10725.9 KIK43759.1 - 0.035 13.9 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) FAD_binding_3 PF01494.19 KIK43760.1 - 2.7e-18 66.4 1.4 8.4e-11 41.7 0.8 2.6 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KIK43760.1 - 1e-10 41.3 0.3 4.6e-06 26.1 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK43760.1 - 6.4e-10 38.3 1.0 2.9e-05 23.0 0.3 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 KIK43760.1 - 3.7e-09 36.2 0.8 7.3e-09 35.2 0.6 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIK43760.1 - 8.5e-09 35.4 3.1 2.3e-05 24.2 1.5 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KIK43760.1 - 1.3e-07 31.4 0.2 1.7e-07 30.9 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIK43760.1 - 4.6e-06 27.1 0.4 0.003 18.1 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIK43760.1 - 4.7e-06 25.9 0.2 2.2e-05 23.7 0.3 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KIK43760.1 - 7.7e-06 26.0 1.1 6.7e-05 23.0 0.2 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIK43760.1 - 3.2e-05 23.3 0.0 4.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIK43760.1 - 0.00024 20.1 0.5 0.0046 15.9 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.12 KIK43760.1 - 0.0049 16.0 1.1 0.057 12.5 0.6 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KIK43760.1 - 0.012 14.9 0.1 0.022 14.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Mrr_cat PF04471.12 KIK43760.1 - 0.016 15.2 0.3 0.049 13.7 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease Thiolase_N PF00108.23 KIK43764.1 - 1.8e-79 266.8 3.2 1.8e-79 266.8 3.2 1.8 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIK43764.1 - 1.4e-45 153.9 0.3 2.6e-45 153.0 0.3 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIK43764.1 - 0.024 14.2 0.5 0.024 14.2 0.5 3.7 4 1 1 5 5 5 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KIK43764.1 - 0.073 12.9 0.5 8.2 6.4 0.0 2.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III TPR_MLP1_2 PF07926.12 KIK43764.1 - 0.19 11.8 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Zn_clus PF00172.18 KIK43769.1 - 5e-05 23.3 10.6 0.00015 21.8 10.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop53 PF07767.11 KIK43770.1 - 0.1 12.0 9.5 0.02 14.3 5.7 1.5 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) PDH PF02153.17 KIK43772.1 - 7.1e-13 48.1 0.0 1.1e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 KIK43772.1 - 2.5e-05 24.5 0.0 4.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KIK43772.1 - 5.6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KIK43772.1 - 0.016 14.9 0.0 0.037 13.7 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 KIK43772.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 ThiF family FOXP-CC PF16159.5 KIK43777.1 - 8.7e-05 23.1 0.5 0.00022 21.8 0.5 1.6 1 0 0 1 1 1 1 FOXP coiled-coil domain zf-C2H2 PF00096.26 KIK43777.1 - 0.052 14.0 7.5 1.5 9.4 0.9 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type IBR PF01485.21 KIK43777.1 - 0.065 13.5 1.3 0.065 13.5 1.3 1.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-H2C2_2 PF13465.6 KIK43777.1 - 0.43 11.1 2.0 0.43 11.1 0.3 2.0 2 0 0 2 2 2 0 Zinc-finger double domain adh_short_C2 PF13561.6 KIK43778.1 - 0.012 15.2 0.0 0.037 13.6 0.1 1.6 1 1 1 2 2 2 0 Enoyl-(Acyl carrier protein) reductase zf-C2H2 PF00096.26 KIK43788.1 - 0.00014 22.1 3.9 0.0098 16.3 0.1 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK43788.1 - 0.00049 20.7 2.0 0.37 11.7 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger IBR PF01485.21 KIK43788.1 - 0.014 15.6 1.1 0.021 15.0 1.1 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF4729 PF15866.5 KIK43788.1 - 0.016 14.5 0.5 0.021 14.1 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4729) zf-H2C2_5 PF13909.6 KIK43788.1 - 0.018 14.7 0.5 0.057 13.2 0.5 1.9 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Zn_ribbon_SprT PF17283.2 KIK43788.1 - 0.024 14.6 1.4 0.052 13.5 1.4 1.6 1 1 0 1 1 1 0 SprT-like zinc ribbon domain FOXP-CC PF16159.5 KIK43788.1 - 0.069 13.8 1.2 0.16 12.7 0.7 1.8 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_2 PF12756.7 KIK43788.1 - 0.16 12.3 1.7 0.26 11.6 1.7 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) WBP-1 PF11669.8 KIK43792.1 - 0.013 16.2 0.1 0.013 16.1 0.1 1.1 1 0 0 1 1 1 0 WW domain-binding protein 1 IBR PF01485.21 KIK43793.1 - 0.0017 18.5 0.9 0.0028 17.8 0.9 1.3 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain zf-C2H2 PF00096.26 KIK43793.1 - 0.0027 18.1 2.8 0.078 13.5 0.4 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK43793.1 - 0.17 12.8 0.8 1.2 10.2 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Tmemb_55A PF09788.9 KIK43793.1 - 0.74 8.8 4.4 1.1 8.3 4.4 1.2 1 0 0 1 1 1 0 Transmembrane protein 55A DUF4158 PF13700.6 KIK43795.1 - 0.082 12.7 0.0 0.09 12.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) PEX-2N PF09263.10 KIK43795.1 - 0.096 13.0 0.1 0.11 12.9 0.1 1.1 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal zf-C2H2 PF00096.26 KIK43796.1 - 8.8e-06 25.9 1.1 0.0009 19.6 0.1 3.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type IBR PF01485.21 KIK43796.1 - 0.0029 17.8 0.2 0.0029 17.8 0.2 2.3 3 0 0 3 3 3 1 IBR domain, a half RING-finger domain zf-H2C2_2 PF13465.6 KIK43796.1 - 0.092 13.2 0.1 0.092 13.2 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK43796.1 - 0.13 13.2 7.3 1.3 10.1 0.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger TetR_C_30 PF17939.1 KIK43796.1 - 0.16 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain adh_short_C2 PF13561.6 KIK43798.1 - 3.2e-37 128.3 0.1 3.7e-37 128.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK43798.1 - 2e-33 115.5 0.1 2.6e-33 115.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK43798.1 - 1.2e-09 38.4 0.2 2.1e-09 37.5 0.2 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KIK43798.1 - 3e-05 23.5 0.0 4.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KIK43798.1 - 0.0021 17.6 0.0 0.0047 16.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK43798.1 - 0.033 14.1 0.0 0.068 13.1 0.0 1.6 2 0 0 2 2 2 0 NAD(P)H-binding DUF1206 PF06724.11 KIK43798.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) RmlD_sub_bind PF04321.17 KIK43798.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KIK43798.1 - 0.15 11.4 0.0 0.54 9.6 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Cellulase PF00150.18 KIK43799.1 - 8.1e-13 48.4 0.1 2.5e-10 40.3 0.0 3.0 2 2 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 KIK43799.1 - 3.3e-09 37.2 0.0 2.7e-08 34.2 0.0 2.5 3 0 0 3 3 3 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_35 PF01301.19 KIK43799.1 - 0.019 14.6 0.1 0.03 14.0 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Pkinase PF00069.25 KIK43800.1 - 9.4e-05 21.9 0.0 0.00023 20.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK43800.1 - 0.13 11.6 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Amidohydro_1 PF01979.20 KIK43801.1 - 1e-06 28.3 0.1 2e-06 27.4 0.1 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 KIK43801.1 - 3.4e-06 27.1 0.0 4.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase CDC73_C PF05179.14 KIK43802.1 - 1e-52 178.0 0.4 1.8e-52 177.2 0.4 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 KIK43802.1 - 1.4e-09 37.8 0.0 0.00035 20.0 0.0 2.3 2 0 0 2 2 2 2 Paf1 complex subunit CDC73 N-terminal OPA3 PF07047.12 KIK43803.1 - 1.7e-43 147.3 0.7 2.2e-43 147.0 0.7 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) HR1 PF02185.16 KIK43803.1 - 0.0023 18.0 0.8 0.0037 17.3 0.1 1.7 2 0 0 2 2 2 1 Hr1 repeat Med11 PF10280.9 KIK43803.1 - 0.026 15.0 0.8 0.065 13.7 0.8 1.7 1 1 0 1 1 1 0 Mediator complex protein THEG PF14912.6 KIK43803.1 - 0.037 14.5 0.1 3.1 8.3 0.1 2.5 2 0 0 2 2 2 0 Testicular haploid expressed repeat TRPM_tetra PF16519.5 KIK43803.1 - 0.054 13.6 0.9 0.11 12.6 0.9 1.6 1 0 0 1 1 1 0 Tetramerisation domain of TRPM HTH_30 PF13556.6 KIK43803.1 - 0.08 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain MbeD_MobD PF04899.12 KIK43803.1 - 0.18 12.0 1.9 0.25 11.5 0.6 1.9 2 0 0 2 2 2 0 MbeD/MobD like Rx_N PF18052.1 KIK43803.1 - 0.37 11.1 2.0 0.78 10.1 0.4 2.0 2 0 0 2 2 2 0 Rx N-terminal domain CCDC-167 PF15188.6 KIK43803.1 - 3 8.2 6.4 2.5 8.5 2.5 2.4 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Peptidase_C48 PF02902.19 KIK43804.1 - 8.2e-12 45.4 0.6 1.5e-11 44.6 0.6 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Aldolase_II PF00596.21 KIK43805.1 - 1.1e-36 126.5 0.0 1.3e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain RsmF_methylt_CI PF17126.5 KIK43805.1 - 0.053 13.6 0.1 3.9 7.6 0.0 3.2 3 1 1 4 4 4 0 RsmF rRNA methyltransferase first C-terminal domain GCV_T PF01571.21 KIK43808.1 - 1.4e-82 277.0 0.0 1.7e-82 276.7 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KIK43808.1 - 2.4e-22 78.6 0.0 4.9e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain RIBIOP_C PF04950.12 KIK43809.1 - 0.051 13.0 0.0 0.051 13.0 0.0 1.0 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal RNase_PH PF01138.21 KIK43812.1 - 1.6e-11 44.8 0.3 1.6e-11 44.8 0.3 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 DUF5585 PF17823.1 KIK43812.1 - 0.045 12.7 1.2 0.056 12.4 1.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Pkinase_Tyr PF07714.17 KIK43814.1 - 1.7e-34 119.3 0.0 2.2e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK43814.1 - 3.1e-25 89.0 0.0 4.2e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KIK43814.1 - 0.0072 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK43814.1 - 0.18 11.1 0.2 0.27 10.6 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KIK43815.1 - 1.6e-33 116.1 0.0 1.9e-33 115.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK43815.1 - 2.1e-31 109.3 0.0 2.4e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KIK43815.1 - 0.00026 20.4 0.0 0.00036 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK43815.1 - 0.057 12.8 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KIK43816.1 - 7.3e-41 140.2 0.0 9.2e-41 139.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK43816.1 - 6.7e-38 130.6 0.0 8.7e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIK43816.1 - 0.005 16.5 0.2 0.051 13.2 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KIK43816.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK43816.1 - 0.098 11.4 0.0 0.098 11.4 0.0 1.6 3 0 0 3 3 3 0 Fungal protein kinase Kinase-like PF14531.6 KIK43816.1 - 0.19 11.0 0.0 0.36 10.1 0.0 1.6 2 0 0 2 2 2 0 Kinase-like CBFD_NFYB_HMF PF00808.23 KIK43818.1 - 7.6e-16 58.2 4.7 6.5e-09 35.9 0.3 2.2 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK43818.1 - 2.6e-07 31.1 0.5 0.0074 16.6 0.4 2.2 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 OrsD PF12013.8 KIK43818.1 - 0.065 13.7 0.0 0.13 12.7 0.0 1.5 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF4400 PF14348.6 KIK43820.1 - 0.11 12.0 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) DUF3237 PF11578.8 KIK43820.1 - 0.15 11.9 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) Pkinase_Tyr PF07714.17 KIK43821.1 - 2.6e-40 138.4 0.0 3.3e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK43821.1 - 1.9e-29 102.8 0.0 2.5e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK43821.1 - 0.0061 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_I6 PF04595.13 KIK43821.1 - 0.022 13.7 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus I6-like family ABC1 PF03109.16 KIK43821.1 - 0.045 13.9 0.0 0.084 13.0 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Kinase-like PF14531.6 KIK43821.1 - 0.08 12.2 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 KIK43822.1 - 5.8e-43 147.1 0.0 7e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK43822.1 - 1.8e-34 119.3 0.0 2.3e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK43822.1 - 5.1e-06 26.0 0.4 9.9e-06 25.0 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIK43822.1 - 0.00053 19.6 0.3 0.0058 16.3 0.2 2.0 1 1 1 2 2 2 1 RIO1 family APH PF01636.23 KIK43822.1 - 0.0021 18.0 0.2 0.0033 17.4 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK43822.1 - 0.0024 17.3 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like ABC1 PF03109.16 KIK43822.1 - 0.036 14.2 0.0 0.067 13.4 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Haspin_kinase PF12330.8 KIK43822.1 - 0.041 12.8 0.0 0.099 11.6 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KIK43822.1 - 0.059 12.1 0.3 0.09 11.5 0.3 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 KIK43823.1 - 1e-37 129.8 0.0 1.3e-37 129.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK43823.1 - 7.4e-37 127.1 0.0 1e-36 126.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIK43823.1 - 0.01 15.5 0.2 0.022 14.4 0.1 1.5 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 KIK43823.1 - 0.018 13.8 0.1 0.026 13.3 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KIK43823.1 - 0.042 13.2 0.1 0.065 12.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIK43823.1 - 0.099 11.9 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 KIK43824.1 - 3.7e-42 144.4 0.0 4.6e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK43824.1 - 3e-37 128.4 0.0 3.8e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK43824.1 - 1.9e-06 27.4 0.0 3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK43824.1 - 7.5e-06 25.0 0.0 1.1e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIK43824.1 - 0.002 17.5 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KIK43824.1 - 0.0037 16.9 0.0 0.0066 16.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIK43824.1 - 0.006 16.5 0.0 0.0095 15.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family BsuBI_PstI_RE PF06616.11 KIK43824.1 - 0.089 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain Seadorna_VP7 PF07387.11 KIK43824.1 - 0.19 10.7 0.1 0.3 10.1 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 KIK43824.1 - 0.2 11.2 0.0 15 5.1 0.0 2.2 1 1 1 2 2 2 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 KIK43824.1 - 0.24 10.3 0.1 3 6.7 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_Tyr PF07714.17 KIK43825.1 - 3e-39 134.9 0.0 4.8e-39 134.2 0.0 1.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK43825.1 - 1.1e-33 116.8 0.0 1.5e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KIK43825.1 - 8.1e-07 28.6 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK43825.1 - 2.3e-06 27.1 0.0 1.1e-05 24.9 0.0 1.8 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIK43825.1 - 0.022 14.4 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KIK43825.1 - 0.042 13.8 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KIK43825.1 - 0.069 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_Tyr PF07714.17 KIK43826.1 - 6.9e-42 143.5 0.0 8.6e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK43826.1 - 9.4e-42 143.2 0.0 1.3e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK43826.1 - 0.00083 18.8 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIK43826.1 - 0.0052 16.4 0.0 0.0095 15.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIK43826.1 - 0.0086 16.0 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.16 KIK43826.1 - 0.03 14.5 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Pkinase_fungal PF17667.1 KIK43826.1 - 0.067 12.0 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase UDPGP PF01704.18 KIK43826.1 - 0.17 10.5 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 UTP--glucose-1-phosphate uridylyltransferase YrbL-PhoP_reg PF10707.9 KIK43826.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Clathrin PF00637.20 KIK43827.1 - 2.5e-15 56.6 0.1 3.2e-11 43.3 0.0 2.9 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.8 KIK43827.1 - 1.5e-13 50.7 0.3 3.2e-13 49.7 0.3 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 KIK43827.1 - 3.7e-08 33.3 10.0 6.9e-08 32.4 10.0 1.5 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 KIK43827.1 - 0.0011 18.7 9.4 0.002 17.9 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KIK43827.1 - 0.054 13.4 1.1 0.11 12.4 1.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KIK43827.1 - 0.058 13.7 6.7 0.11 12.8 6.7 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KIK43827.1 - 0.064 13.6 9.4 0.12 12.7 9.4 1.5 1 0 0 1 1 1 0 Ring finger domain TetR_C_27 PF17935.1 KIK43827.1 - 0.083 13.0 0.1 25 5.0 0.1 2.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TPR_11 PF13414.6 KIK43827.1 - 0.099 12.3 0.2 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 TPR repeat zf-RING_5 PF14634.6 KIK43827.1 - 0.13 12.2 8.3 0.22 11.5 8.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain TPR_2 PF07719.17 KIK43827.1 - 0.63 10.3 2.9 5 7.5 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat zf-RING_UBOX PF13445.6 KIK43827.1 - 3.8 7.6 6.6 7.6 6.7 6.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger TB2_DP1_HVA22 PF03134.19 KIK43834.1 - 1.3e-25 89.1 7.1 1.3e-25 89.1 7.1 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Ost5 PF05251.12 KIK43835.1 - 3.2e-20 72.1 7.9 3.7e-20 72.0 7.9 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 QCR10 PF09796.9 KIK43835.1 - 0.15 12.1 2.6 7 6.8 0.2 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) TFIIS_C PF01096.18 KIK43836.1 - 2.1e-17 62.6 0.9 2.1e-17 62.6 0.9 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KIK43836.1 - 3.5e-11 42.8 6.8 6.1e-10 38.8 0.9 3.0 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit DZR PF12773.7 KIK43836.1 - 4.8e-05 23.3 8.2 0.0027 17.7 0.5 2.5 2 1 0 2 2 2 2 Double zinc ribbon zinc_ribbon_10 PF10058.9 KIK43836.1 - 0.0025 17.5 4.0 7.4 6.4 0.0 4.0 4 0 0 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn_Tnp_IS1595 PF12760.7 KIK43836.1 - 0.0026 17.7 11.1 0.0048 16.9 0.7 2.9 2 1 1 3 3 3 1 Transposase zinc-ribbon domain zf-RING_7 PF02591.15 KIK43836.1 - 0.0028 17.8 6.7 0.28 11.4 0.0 4.0 4 0 0 4 4 4 1 C4-type zinc ribbon domain PHD PF00628.29 KIK43836.1 - 0.0059 16.5 6.7 0.35 10.8 0.5 2.4 2 0 0 2 2 2 2 PHD-finger IBR PF01485.21 KIK43836.1 - 0.0063 16.7 8.5 0.034 14.4 0.3 2.5 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain OrfB_Zn_ribbon PF07282.11 KIK43836.1 - 0.0073 16.2 8.0 0.19 11.6 0.3 2.5 2 1 0 2 2 2 2 Putative transposase DNA-binding domain PhnA_Zn_Ribbon PF08274.12 KIK43836.1 - 0.014 15.3 12.7 6.4 6.8 3.8 3.7 3 1 0 3 3 3 0 PhnA Zinc-Ribbon Baculo_LEF5_C PF11792.8 KIK43836.1 - 0.025 14.2 0.5 0.025 14.2 0.5 2.6 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain NPM1-C PF16276.5 KIK43836.1 - 0.028 14.4 0.3 0.054 13.5 0.3 1.4 1 0 0 1 1 1 0 Nucleophosmin C-terminal domain Mu-like_Com PF10122.9 KIK43836.1 - 0.032 13.7 2.9 2.9 7.4 0.0 2.6 3 0 0 3 3 2 0 Mu-like prophage protein Com Zn-ribbon_8 PF09723.10 KIK43836.1 - 0.046 13.8 11.7 5.4 7.2 0.1 4.0 3 1 0 3 3 3 0 Zinc ribbon domain Nudix_N_2 PF14803.6 KIK43836.1 - 0.059 13.3 2.4 0.059 13.3 2.4 3.3 2 2 0 2 2 2 0 Nudix N-terminal zf-C4pol PF14260.6 KIK43836.1 - 0.063 13.8 4.1 2.2 8.8 4.1 2.4 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Cys_rich_CPCC PF14206.6 KIK43836.1 - 0.076 12.8 6.0 0.11 12.3 0.1 2.4 2 1 0 2 2 2 0 Cysteine-rich CPCC zinc_ribbon_4 PF13717.6 KIK43836.1 - 0.094 12.7 10.1 9.6 6.2 0.2 4.1 4 0 0 4 4 4 0 zinc-ribbon domain Lar_restr_allev PF14354.6 KIK43836.1 - 0.1 13.0 11.3 2.2 8.7 0.7 2.9 2 1 0 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.6 KIK43836.1 - 0.25 11.1 15.9 1.2 8.9 4.4 3.5 3 1 0 3 3 2 0 zinc-ribbon domain HscB_4_cys PF18256.1 KIK43836.1 - 0.34 10.8 0.1 0.34 10.8 0.1 2.9 4 0 0 4 4 3 0 Co-chaperone HscB tetracysteine metal binding motif zf-IS66 PF13005.7 KIK43836.1 - 0.46 10.9 12.4 1 9.8 2.1 3.4 3 1 0 3 3 3 0 zinc-finger binding domain of transposase IS66 zf-NADH-PPase PF09297.11 KIK43836.1 - 0.49 10.1 14.7 0.12 12.1 1.7 3.4 3 1 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain UPF0547 PF10571.9 KIK43836.1 - 0.51 10.5 0.2 0.51 10.5 0.2 3.5 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.6 KIK43836.1 - 0.62 9.6 18.4 0.91 9.0 0.3 3.8 3 1 0 3 3 3 0 zinc-ribbon domain zf-UBR PF02207.20 KIK43836.1 - 0.79 9.9 8.0 0.77 10.0 0.3 3.0 2 1 1 3 3 3 0 Putative zinc finger in N-recognin (UBR box) Rpr2 PF04032.16 KIK43836.1 - 0.79 10.1 5.8 6 7.2 5.8 2.4 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-FPG_IleRS PF06827.14 KIK43836.1 - 0.86 9.5 10.9 2.3 8.1 2.2 3.1 3 1 0 3 3 2 0 Zinc finger found in FPG and IleRS DUF3268 PF11672.8 KIK43836.1 - 0.87 9.9 7.1 0.13 12.6 1.1 2.3 2 1 0 2 2 2 0 zinc-finger-containing domain zf-RING_10 PF16685.5 KIK43836.1 - 0.95 9.7 7.5 1.6 8.9 0.5 2.9 2 1 1 3 3 3 0 zinc RING finger of MSL2 DUF35_N PF12172.8 KIK43836.1 - 1.7 8.6 9.4 6.2 6.8 0.2 3.4 4 0 0 4 4 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) GFA PF04828.14 KIK43836.1 - 1.8 8.9 7.7 1.4 9.3 0.4 2.6 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.12 KIK43836.1 - 2 8.6 9.3 0.99 9.6 1.1 3.1 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf_UBZ PF18439.1 KIK43836.1 - 2 8.1 10.2 11 5.7 0.0 4.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-LITAF-like PF10601.9 KIK43836.1 - 3.8 7.8 10.1 19 5.6 0.2 4.0 4 1 0 4 4 4 0 LITAF-like zinc ribbon domain RecR PF02132.15 KIK43836.1 - 5.4 6.7 8.3 1.2 8.7 0.5 2.7 2 1 0 2 2 2 0 RecR protein PADR1 PF08063.12 KIK43836.1 - 5.7 6.8 9.0 6.6 6.6 0.2 3.5 4 0 0 4 4 4 0 PADR1 (NUC008) domain XAF1_C PF18608.1 KIK43836.1 - 5.9 6.5 7.5 4.1 7.0 0.1 3.5 4 0 0 4 4 4 0 XIAP-associated factor 1 C-terminal domain Rubredoxin_2 PF18073.1 KIK43836.1 - 5.9 6.7 14.5 10 6.0 0.1 4.0 4 0 0 4 4 4 0 Rubredoxin metal binding domain zinc_ribbon_13 PF09855.9 KIK43836.1 - 9.2 6.5 10.9 4.8 7.4 0.1 3.3 3 1 1 4 4 4 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Peptidase_M1 PF01433.20 KIK43838.1 - 1.1e-35 123.2 0.1 1.5e-35 122.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KIK43838.1 - 1.9e-28 98.8 0.0 3.5e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KIK43838.1 - 2.8e-25 89.6 0.0 5.3e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ArfGap PF01412.18 KIK43839.1 - 5e-41 139.4 0.3 8.8e-41 138.7 0.3 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf GET2 PF08690.10 KIK43840.1 - 6.3e-08 32.7 0.0 3.5e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 GET complex subunit GET2 L51_S25_CI-B8 PF05047.16 KIK43841.1 - 3e-08 33.5 0.2 5.1e-08 32.7 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain YL1 PF05764.13 KIK43842.1 - 6.1e-38 131.3 20.7 7.9e-38 130.9 20.7 1.1 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 KIK43842.1 - 4.3e-13 48.8 0.4 7.2e-13 48.1 0.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain MMPL PF03176.15 KIK43842.1 - 7.9 5.3 8.1 3.6 6.4 6.0 1.5 1 1 0 1 1 1 0 MMPL family BCIP PF13862.6 KIK43845.1 - 1e-63 214.9 0.0 1.2e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Vps35 PF03635.17 KIK43846.1 - 8.3e-302 1003.2 0.0 9.5e-302 1003.0 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Ribonuc_L-PSP PF01042.21 KIK43846.1 - 0.081 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Endoribonuclease L-PSP PDZ_5 PF17817.1 KIK43848.1 - 0.049 13.9 0.2 0.24 11.7 0.0 2.3 2 0 0 2 2 2 0 PDZ domain PAM2 PF07145.15 KIK43848.1 - 0.2 11.4 1.5 0.55 10.0 0.3 2.5 2 0 0 2 2 2 0 Ataxin-2 C-terminal region RNA_pol_Rpb1_1 PF04997.12 KIK43849.1 - 2.7e-109 365.3 0.0 3.8e-109 364.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KIK43849.1 - 1.7e-104 349.0 0.0 2.3e-104 348.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KIK43849.1 - 7e-74 247.6 0.0 1.2e-73 246.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KIK43849.1 - 1.5e-63 214.2 0.1 2.3e-63 213.5 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 KIK43849.1 - 1e-49 168.5 0.0 2.5e-49 167.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 KIK43849.1 - 7.5e-48 162.0 0.0 1.6e-47 160.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 KIK43849.1 - 2.8e-36 123.7 0.0 5.6e-36 122.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KIK43849.1 - 1.5e-06 28.2 189.2 0.026 14.9 10.5 13.3 6 1 11 17 17 17 13 RNA polymerase Rpb1 C-terminal repeat VHS PF00790.19 KIK43851.1 - 1.6e-44 151.2 0.4 8e-43 145.7 0.0 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KIK43851.1 - 6.1e-17 61.5 7.1 1e-16 60.8 7.1 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KIK43851.1 - 9.9e-05 22.0 13.4 0.014 15.3 3.4 3.2 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.16 KIK43851.1 - 0.00098 19.3 4.0 0.0023 18.2 4.0 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger GAT PF03127.14 KIK43851.1 - 0.025 14.9 0.2 0.025 14.9 0.2 2.3 3 0 0 3 3 3 0 GAT domain Exo70 PF03081.15 KIK43851.1 - 0.17 10.9 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Zn-ribbon_8 PF09723.10 KIK43851.1 - 0.24 11.6 2.7 0.7 10.0 2.7 1.9 1 1 0 1 1 1 0 Zinc ribbon domain C1_1 PF00130.22 KIK43851.1 - 0.24 11.3 5.8 0.083 12.8 1.7 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 KIK43851.1 - 0.27 11.3 9.5 6.5 6.9 9.3 2.3 1 1 1 2 2 2 0 Double zinc ribbon Joubert PF15392.6 KIK43851.1 - 0.7 9.6 6.8 0.096 12.4 1.9 1.9 2 0 0 2 2 2 0 Joubert syndrome-associated zinc-ribbons_6 PF07191.12 KIK43851.1 - 6.3 6.9 8.4 26 4.9 8.4 1.9 1 1 0 1 1 1 0 zinc-ribbons DAO PF01266.24 KIK43852.1 - 1.9e-27 96.8 0.8 2.8e-27 96.2 0.8 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK43852.1 - 6.8e-07 28.7 0.1 9.4e-07 28.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIK43852.1 - 0.00042 20.5 0.1 0.0011 19.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIK43852.1 - 0.001 18.4 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KIK43852.1 - 0.0058 15.9 0.0 0.0084 15.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK43852.1 - 0.058 12.4 0.4 0.12 11.4 0.2 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein MutS_V PF00488.21 KIK43853.1 - 9.4e-59 198.6 0.0 2.6e-58 197.2 0.0 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KIK43853.1 - 1.2e-30 107.2 3.8 1.9e-30 106.5 2.3 2.0 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 KIK43853.1 - 1.7e-05 25.1 0.0 5.6e-05 23.4 0.0 2.0 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KIK43853.1 - 0.00023 21.5 0.0 0.00076 19.8 0.0 2.0 1 1 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 KIK43853.1 - 0.019 14.5 0.0 0.047 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pro_dh PF01619.18 KIK43854.1 - 3.8e-49 167.8 0.0 1.3e-25 90.5 0.0 3.2 2 1 1 3 3 3 3 Proline dehydrogenase TIP120 PF08623.10 KIK43855.1 - 6.5e-47 159.4 0.4 7.5e-46 156.0 0.0 3.0 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KIK43855.1 - 1.2e-17 64.1 13.6 0.00055 20.3 0.0 9.4 8 2 2 10 10 10 4 HEAT repeats HEAT PF02985.22 KIK43855.1 - 1.7e-11 43.3 28.1 0.1 12.9 0.0 13.3 16 0 0 16 16 15 2 HEAT repeat Cnd1 PF12717.7 KIK43855.1 - 3.1e-09 37.1 3.0 0.0034 17.4 0.1 7.0 5 2 1 7 7 7 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KIK43855.1 - 4.8e-09 36.5 23.6 0.67 10.5 0.1 10.5 10 2 2 12 12 11 4 HEAT-like repeat CLASP_N PF12348.8 KIK43855.1 - 5.3e-09 36.0 1.5 0.001 18.7 0.0 5.9 5 1 0 6 6 6 1 CLASP N terminal Adaptin_N PF01602.20 KIK43855.1 - 9.4e-09 34.4 12.7 0.026 13.1 0.1 5.8 4 2 1 6 6 6 3 Adaptin N terminal region DUF4042 PF13251.6 KIK43855.1 - 5e-06 26.3 3.3 1.7 8.3 0.0 6.8 7 0 0 7 7 7 1 Domain of unknown function (DUF4042) RTP1_C1 PF10363.9 KIK43855.1 - 0.00021 21.5 6.7 0.072 13.3 0.1 5.0 5 2 0 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 Telomere_reg-2 PF10193.9 KIK43855.1 - 0.00022 21.7 2.3 1.1 9.8 0.1 4.2 3 0 0 3 3 3 2 Telomere length regulation protein Vac14_Fab1_bd PF12755.7 KIK43855.1 - 0.00028 21.4 0.6 22 5.7 0.1 6.0 7 1 1 8 8 7 0 Vacuolar 14 Fab1-binding region TAF6_C PF07571.13 KIK43855.1 - 0.00031 21.0 0.8 0.16 12.3 0.0 4.5 4 2 0 4 4 3 1 TAF6 C-terminal HEAT repeat domain Tti2 PF10521.9 KIK43855.1 - 0.00039 20.1 6.0 4.9 6.6 0.1 5.7 5 1 0 5 5 5 1 Tti2 family V-ATPase_H_C PF11698.8 KIK43855.1 - 0.0034 17.5 0.9 0.69 10.0 0.1 4.3 4 1 0 5 5 5 1 V-ATPase subunit H DUF3385 PF11865.8 KIK43855.1 - 0.0096 15.8 5.1 0.16 11.9 0.0 4.7 6 0 0 6 6 6 1 Domain of unknown function (DUF3385) API5 PF05918.11 KIK43855.1 - 0.092 11.5 2.0 8 5.1 0.0 2.9 3 1 0 4 4 4 0 Apoptosis inhibitory protein 5 (API5) YkuD PF03734.14 KIK43856.1 - 0.075 13.4 0.1 0.1 13.0 0.1 1.3 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain Pkinase PF00069.25 KIK43857.1 - 2.4e-40 138.6 0.0 2.9e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK43857.1 - 3.7e-21 75.6 0.0 5e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK43857.1 - 8.3e-06 25.3 0.0 2.8e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK43857.1 - 0.0004 19.8 0.0 0.00066 19.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIK43857.1 - 0.0028 17.3 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIK43857.1 - 0.0046 16.9 0.0 0.0076 16.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK43857.1 - 0.027 13.3 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TMEM100 PF16311.5 KIK43858.1 - 0.076 12.6 0.6 0.12 12.0 0.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 100 MOZ_SAS PF01853.18 KIK43859.1 - 3.7e-62 209.2 0.0 8.7e-62 208.0 0.0 1.5 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 KIK43859.1 - 6.4e-19 67.3 2.3 3.5e-09 36.1 0.0 2.7 2 0 0 2 2 2 2 MYST family zinc finger domain Tudor-knot PF11717.8 KIK43859.1 - 8.6e-10 38.4 0.0 1.6e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KIK43859.1 - 0.0013 19.1 0.0 0.0029 18.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK43859.1 - 0.0076 16.5 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ribosomal_L19e PF01280.20 KIK43860.1 - 9.3e-61 204.1 9.8 9.3e-61 204.1 9.8 1.7 1 1 1 2 2 2 1 Ribosomal protein L19e S4 PF01479.25 KIK43860.1 - 0.00075 19.2 0.0 0.0036 17.0 0.0 2.1 2 0 0 2 2 2 1 S4 domain Pkinase PF00069.25 KIK43861.1 - 2.6e-56 190.9 0.0 3.6e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK43861.1 - 1.7e-22 80.0 0.0 2.2e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK43861.1 - 0.00034 20.0 0.6 0.0016 17.8 0.1 2.3 2 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KIK43861.1 - 0.032 13.9 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 AAA PF00004.29 KIK43862.1 - 7.5e-42 142.9 0.0 1.2e-41 142.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KIK43862.1 - 3.2e-27 94.3 0.3 1.1e-26 92.6 0.3 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KIK43862.1 - 7.4e-19 67.6 9.8 1.4e-18 66.7 9.8 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KIK43862.1 - 4.4e-07 29.6 0.0 1.2e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KIK43862.1 - 2.5e-06 28.0 0.4 0.00084 19.8 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KIK43862.1 - 9.3e-06 25.5 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KIK43862.1 - 1.2e-05 25.5 1.0 0.0025 18.1 0.2 2.7 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KIK43862.1 - 1.6e-05 24.9 0.0 6.1e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KIK43862.1 - 5.8e-05 22.9 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 KIK43862.1 - 8.1e-05 22.7 0.1 0.00029 20.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KIK43862.1 - 0.00012 22.6 0.6 0.0037 17.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KIK43862.1 - 0.00069 18.9 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KIK43862.1 - 0.00096 19.3 0.1 0.0048 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KIK43862.1 - 0.0018 18.4 0.1 0.0063 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 KIK43862.1 - 0.0021 17.8 0.1 0.0061 16.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KIK43862.1 - 0.0026 17.0 0.0 0.0052 16.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.6 KIK43862.1 - 0.0038 17.7 0.1 0.036 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KIK43862.1 - 0.004 17.5 0.0 0.011 16.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase ATPase PF06745.13 KIK43862.1 - 0.0083 15.5 0.1 3.2 7.1 0.0 2.4 1 1 1 2 2 2 1 KaiC AAA_25 PF13481.6 KIK43862.1 - 0.01 15.4 0.3 0.82 9.2 0.1 2.3 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 KIK43862.1 - 0.041 13.8 0.0 0.25 11.2 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 KIK43862.1 - 0.047 13.1 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 KIK43862.1 - 0.061 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 KIK43862.1 - 0.063 12.7 0.1 0.18 11.3 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein Torsin PF06309.11 KIK43862.1 - 0.064 13.4 0.0 0.44 10.7 0.0 2.2 2 0 0 2 2 2 0 Torsin AAA_7 PF12775.7 KIK43862.1 - 0.072 12.6 0.0 0.23 11.0 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region ParB PF08775.10 KIK43862.1 - 0.12 12.9 2.4 18 5.8 0.0 2.8 3 0 0 3 3 2 0 ParB family ATPase_2 PF01637.18 KIK43862.1 - 0.13 12.1 4.4 1.5 8.7 0.0 2.9 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 KIK43862.1 - 0.17 12.0 0.0 0.51 10.5 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain Med9 PF07544.13 KIK43863.1 - 5.2e-06 26.5 0.2 7e-06 26.0 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 dbPDZ_assoc PF16610.5 KIK43863.1 - 0.025 14.8 0.1 4 7.7 0.0 2.4 2 0 0 2 2 2 0 Unstructured region between two PDZ domains on Dlg5 Plavaka PF18759.1 KIK43864.1 - 2.6e-105 352.2 0.0 4.2e-105 351.5 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase DUF5069 PF16798.5 KIK43865.1 - 0.039 14.2 0.1 0.072 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5069) CxC6 PF18721.1 KIK43867.1 - 1.3e-21 76.6 8.8 1.8e-21 76.2 8.8 1.2 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases Fer2_4 PF13510.6 KIK43867.1 - 0.11 12.5 3.6 0.3 11.2 2.7 1.9 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Pkinase PF00069.25 KIK43869.1 - 3e-72 243.1 0.0 4.2e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK43869.1 - 1.2e-41 142.7 0.0 1.7e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK43869.1 - 2.6e-11 43.4 0.0 3.8e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK43869.1 - 0.001 18.5 0.2 0.002 17.5 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIK43869.1 - 0.058 12.3 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KIK43869.1 - 0.12 12.3 0.1 0.35 10.7 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family UbiA PF01040.18 KIK43871.1 - 1.1e-28 100.2 3.4 1.7e-28 99.7 3.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Trp_oprn_chp PF09534.10 KIK43874.1 - 0.084 12.7 4.8 0.12 12.2 2.9 1.9 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RseC_MucC PF04246.12 KIK43874.1 - 0.21 11.5 6.0 6.4 6.7 0.2 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF4131 PF13567.6 KIK43874.1 - 5.4 6.6 7.8 1.2 8.7 3.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SOBP PF15279.6 KIK43875.1 - 3.3 8.2 22.3 3.9 8.0 22.3 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein GREB1 PF15782.5 KIK43875.1 - 7.9 3.4 8.6 8.3 3.4 8.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Redoxin PF08534.10 KIK43876.1 - 1.1e-36 125.7 0.0 1.3e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KIK43876.1 - 5.3e-11 42.5 0.0 6.5e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Pil1 PF13805.6 KIK43878.1 - 0.00018 21.1 2.2 0.00022 20.8 2.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Fez1 PF06818.15 KIK43878.1 - 0.00023 21.7 3.0 0.0003 21.3 3.0 1.1 1 0 0 1 1 1 1 Fez1 Sec34 PF04136.15 KIK43878.1 - 0.0015 18.4 2.4 0.0041 17.0 1.5 1.9 1 1 1 2 2 2 1 Sec34-like family UPF0242 PF06785.11 KIK43878.1 - 0.0015 18.7 0.8 0.0017 18.5 0.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Dor1 PF04124.12 KIK43878.1 - 0.0022 16.7 2.6 0.0026 16.5 2.6 1.2 1 0 0 1 1 1 1 Dor1-like family DUF4618 PF15397.6 KIK43878.1 - 0.0044 16.5 1.0 0.0057 16.1 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Syntaxin_2 PF14523.6 KIK43878.1 - 0.0079 16.5 2.0 1.6 9.2 0.7 2.3 1 1 0 2 2 2 1 Syntaxin-like protein PHM7_cyt PF14703.6 KIK43878.1 - 0.0091 16.2 0.5 0.012 15.9 0.5 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Occludin_ELL PF07303.13 KIK43878.1 - 0.011 16.4 0.6 0.027 15.2 0.4 1.7 1 1 0 1 1 1 0 Occludin homology domain FadA PF09403.10 KIK43878.1 - 0.013 16.0 0.8 0.02 15.3 0.8 1.3 1 0 0 1 1 1 0 Adhesion protein FadA XhlA PF10779.9 KIK43878.1 - 0.02 15.1 0.9 0.23 11.7 0.4 2.4 2 1 0 2 2 2 0 Haemolysin XhlA Spc7 PF08317.11 KIK43878.1 - 0.02 13.8 2.1 0.025 13.5 2.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DHR10 PF18595.1 KIK43878.1 - 0.023 14.8 7.9 0.086 12.9 8.2 1.8 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Fib_alpha PF08702.10 KIK43878.1 - 0.025 14.7 1.4 0.032 14.4 1.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RGCC PF15151.6 KIK43878.1 - 0.037 14.2 1.0 0.35 11.1 1.0 2.0 1 1 0 1 1 1 0 Response gene to complement 32 protein family DUF1664 PF07889.12 KIK43878.1 - 0.06 13.4 0.9 0.085 12.9 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Phage_GPO PF05929.11 KIK43878.1 - 0.061 13.0 2.2 0.067 12.8 2.2 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase CK2S PF15011.6 KIK43878.1 - 0.074 12.9 2.4 0.11 12.4 2.4 1.2 1 0 0 1 1 1 0 Casein Kinase 2 substrate APG6_N PF17675.1 KIK43878.1 - 0.11 13.1 3.5 0.17 12.4 3.5 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region EMP24_GP25L PF01105.24 KIK43878.1 - 0.11 12.4 4.3 4.9 7.1 4.3 2.1 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD CLZ PF16526.5 KIK43878.1 - 0.12 12.7 3.4 0.35 11.2 0.7 2.7 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF724 PF05266.14 KIK43878.1 - 0.13 12.1 2.0 0.15 11.8 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TMPIT PF07851.13 KIK43878.1 - 0.14 11.4 2.6 0.17 11.1 2.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein NPV_P10 PF05531.12 KIK43878.1 - 0.15 12.6 1.0 0.72 10.4 1.0 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 KIK43878.1 - 0.19 11.2 3.4 0.22 11.1 3.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-K PF11802.8 KIK43878.1 - 0.25 10.9 2.6 0.4 10.2 2.6 1.4 1 1 0 1 1 1 0 Centromere-associated protein K DUF641 PF04859.12 KIK43878.1 - 0.29 11.5 4.4 0.26 11.6 2.0 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Synaptobrevin PF00957.21 KIK43878.1 - 0.32 10.8 8.1 0.25 11.2 3.2 2.6 2 1 1 3 3 2 0 Synaptobrevin Med9 PF07544.13 KIK43878.1 - 0.47 10.6 3.5 4.4 7.5 4.0 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 FUSC PF04632.12 KIK43878.1 - 0.6 8.6 4.9 0.71 8.3 4.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family FliD_N PF02465.18 KIK43878.1 - 0.91 10.3 4.4 1.1 10.1 1.5 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Dimer_Tnp_hAT PF05699.14 KIK43880.1 - 9e-15 54.2 0.0 2.3e-14 52.9 0.0 1.6 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region UbiA PF01040.18 KIK43881.1 - 1.5e-29 103.1 4.2 1.8e-29 102.8 4.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family UbiA PF01040.18 KIK43882.1 - 1.6e-21 76.8 5.9 2e-21 76.4 5.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Solute_trans_a PF03619.16 KIK43883.1 - 6.4e-97 324.2 10.2 7.8e-97 323.9 10.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha OFeT_1 PF16955.5 KIK43883.1 - 0.24 11.1 4.1 0.49 10.0 4.1 1.4 1 0 0 1 1 1 0 Ferrous iron uptake permease, iron-lead transporter DUF1356 PF07092.12 KIK43883.1 - 0.31 10.3 0.7 12 5.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) Pil1 PF13805.6 KIK43884.1 - 3.3e-22 79.2 0.4 6.9e-22 78.2 0.4 1.5 1 0 0 1 1 1 1 Eisosome component PIL1 Seryl_tRNA_N PF02403.22 KIK43884.1 - 0.27 11.5 1.7 0.57 10.4 1.7 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DHR10 PF18595.1 KIK43884.1 - 0.45 10.6 3.4 1.9 8.6 3.6 1.9 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Kelch_3 PF13415.6 KIK43885.1 - 4.1e-20 71.6 13.9 9.1e-06 25.8 0.0 6.4 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KIK43885.1 - 8.1e-17 61.0 3.8 3e-08 33.5 0.0 5.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KIK43885.1 - 1e-12 47.7 2.3 0.0044 17.0 0.1 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 KIK43885.1 - 2.3e-11 43.1 0.5 9.4e-07 28.3 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 KIK43885.1 - 3.2e-08 33.2 8.3 0.02 14.8 0.0 5.6 6 1 0 6 6 6 2 Kelch motif Kelch_6 PF13964.6 KIK43885.1 - 5.8e-08 32.7 6.5 0.0088 16.3 0.2 5.4 5 1 0 5 5 5 2 Kelch motif PQQ_3 PF13570.6 KIK43885.1 - 0.002 18.5 1.7 13 6.4 0.4 4.4 4 1 0 4 4 4 2 PQQ-like domain adh_short PF00106.25 KIK43888.1 - 3.8e-52 176.6 0.6 4.7e-52 176.3 0.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK43888.1 - 1.2e-47 162.5 0.1 1.5e-47 162.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK43888.1 - 5.2e-11 42.8 0.3 7.9e-11 42.2 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK43888.1 - 0.1 12.1 2.7 7.9 5.9 2.7 2.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 KIK43889.1 - 7.4e-56 189.3 1.0 7.2e-55 186.1 1.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK43889.1 - 5.4e-51 172.8 1.7 7.8e-51 172.3 1.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK43889.1 - 2.2e-11 44.0 0.7 3.5e-11 43.3 0.7 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KIK43891.1 - 8.5e-60 202.2 2.7 1.5e-59 201.4 2.7 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK43891.1 - 4.3e-54 183.0 1.9 6.6e-54 182.3 1.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK43891.1 - 7.4e-11 42.3 0.6 1.2e-10 41.6 0.6 1.4 1 0 0 1 1 1 1 KR domain PmbA_TldD PF01523.16 KIK43891.1 - 0.0063 16.4 0.2 0.008 16.0 0.2 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase VirE2 PF07229.12 KIK43891.1 - 0.18 10.4 0.0 0.26 9.9 0.0 1.1 1 0 0 1 1 1 0 VirE2 adh_short_C2 PF13561.6 KIK43892.1 - 3.9e-56 190.2 1.1 5.3e-56 189.8 1.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK43892.1 - 5.4e-53 179.4 0.6 6.6e-53 179.1 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK43892.1 - 1.7e-09 37.8 0.7 4.3e-09 36.5 0.7 1.7 1 1 1 2 2 2 1 KR domain HHH_5 PF14520.6 KIK43892.1 - 0.085 13.5 2.4 0.42 11.3 0.1 2.9 4 0 0 4 4 4 0 Helix-hairpin-helix domain Epimerase PF01370.21 KIK43892.1 - 0.11 12.0 0.2 0.28 10.6 0.2 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TIM PF00121.18 KIK43893.1 - 1.9e-87 292.7 0.0 2.1e-87 292.5 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 KIK43893.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 CutC family Beach PF02138.18 KIK43894.1 - 1.5e-106 355.8 0.0 2.9e-106 354.9 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.6 KIK43894.1 - 2.1e-09 37.7 1.2 3.1e-09 37.2 0.1 1.8 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 KIK43894.1 - 1e-08 35.7 6.0 0.01 16.7 1.9 4.4 3 0 0 3 3 3 3 WD domain, G-beta repeat PH_BEACH PF14844.6 KIK43894.1 - 2.8e-07 30.6 0.0 3.3e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 KIK43894.1 - 4.3e-06 26.2 2.6 0.00014 21.3 0.5 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4704) Nup160 PF11715.8 KIK43894.1 - 0.016 13.9 0.1 0.027 13.1 0.1 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 CENP-O PF09496.10 KIK43896.1 - 3.9 7.4 8.3 0.51 10.3 3.3 2.0 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component KLRAQ PF10205.9 KIK43896.1 - 4.1 7.7 9.7 1 9.7 3.0 2.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein TMF_TATA_bd PF12325.8 KIK43896.1 - 7.8 6.8 21.0 0.23 11.7 1.3 4.4 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding Crr6 PF08847.11 KIK43897.1 - 0.078 12.6 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Chlororespiratory reduction 6 LAG1-DNAbind PF09271.11 KIK43897.1 - 0.11 13.1 0.0 0.19 12.4 0.0 1.4 1 0 0 1 1 1 0 LAG1, DNA binding DUF973 PF06157.11 KIK43897.1 - 0.15 11.0 9.6 0.21 10.6 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Cytochrom_B561 PF03188.16 KIK43897.1 - 0.48 10.6 4.9 2.2 8.4 4.9 2.1 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 DUF4064 PF13273.6 KIK43897.1 - 1 9.7 8.3 83 3.5 9.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF3099 PF11298.8 KIK43897.1 - 1.1 9.4 0.1 1.1 9.4 0.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3099) FtsX PF02687.21 KIK43897.1 - 2.5 8.6 17.3 1.3 9.5 1.1 2.8 1 1 2 3 3 3 0 FtsX-like permease family DUF3592 PF12158.8 KIK43897.1 - 3 7.9 4.8 9.3 6.3 0.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3592) AA_permease_2 PF13520.6 KIK43898.1 - 1.1e-63 215.6 54.5 1.3e-63 215.4 54.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK43898.1 - 7.7e-15 54.4 49.4 1.1e-14 54.0 49.4 1.2 1 0 0 1 1 1 1 Amino acid permease Epiglycanin_C PF14654.6 KIK43898.1 - 0.088 12.9 0.2 0.28 11.2 0.2 1.9 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region ADIP PF11559.8 KIK43899.1 - 0.054 13.6 2.2 0.77 9.8 0.1 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding BRE1 PF08647.11 KIK43899.1 - 0.079 13.0 0.8 0.19 11.8 0.8 1.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase FUSC PF04632.12 KIK43899.1 - 0.55 8.7 3.1 0.73 8.3 3.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family AA_permease_2 PF13520.6 KIK43900.1 - 4.7e-67 226.7 50.4 5.5e-67 226.4 50.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK43900.1 - 4.3e-14 52.0 43.1 6.8e-14 51.3 43.1 1.2 1 0 0 1 1 1 1 Amino acid permease Oxidored_FMN PF00724.20 KIK43902.1 - 1.6e-93 313.7 0.0 1.8e-93 313.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 KIK43903.1 - 1.2e-93 314.1 0.0 1.4e-93 313.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Integrase_H2C2 PF17921.1 KIK43905.1 - 1.5e-05 25.0 0.0 3.9e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 KIK43905.1 - 9.8e-05 22.5 0.0 0.00016 21.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 KIK43905.1 - 0.066 13.4 0.2 0.16 12.2 0.2 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 KIK43906.1 - 1.6e-09 37.7 0.0 1.9e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PP2C_2 PF13672.6 KIK43906.1 - 0.081 12.5 0.0 0.082 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein phosphatase 2C CLP1_P PF16575.5 KIK43906.1 - 0.1 12.4 0.0 0.11 12.3 0.0 1.0 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DnaB_2 PF07261.11 KIK43907.1 - 0.022 14.5 0.0 6.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Replication initiation and membrane attachment zf-CCHC PF00098.23 KIK43909.1 - 0.01 15.9 6.0 0.016 15.3 6.0 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 KIK43909.1 - 0.1 12.4 2.7 0.17 11.6 2.7 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 KIK43909.1 - 0.46 10.4 3.2 0.98 9.3 3.2 1.7 1 1 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 KIK43909.1 - 0.95 9.3 4.3 1.5 8.7 4.3 1.3 1 0 0 1 1 1 0 Zinc knuckle CLIP1_ZNF PF16641.5 KIK43909.1 - 1.9 8.5 5.6 2.9 7.9 5.6 1.3 1 0 0 1 1 1 0 CLIP1 zinc knuckle Peptidase_U57 PF05582.12 KIK43911.1 - 0.011 15.1 0.7 0.011 15.0 0.7 1.0 1 0 0 1 1 1 0 YabG peptidase U57 PP2C PF00481.21 KIK43914.1 - 3.2e-44 151.5 0.0 5.2e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 KIK43914.1 - 5.3e-24 83.7 33.0 2.9e-12 46.2 4.6 5.4 4 1 2 6 6 6 5 Leucine rich repeat Guanylate_cyc PF00211.20 KIK43914.1 - 9.3e-21 74.3 0.0 1.6e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_4 PF12799.7 KIK43914.1 - 3.2e-18 65.5 29.0 2.4e-07 30.9 0.3 5.8 4 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KIK43914.1 - 5.2e-05 23.2 16.5 4.5 8.2 0.0 7.6 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_9 PF14580.6 KIK43914.1 - 0.043 13.3 2.3 0.14 11.6 0.9 2.3 2 0 0 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 KIK43914.1 - 0.58 10.4 23.0 1 9.6 0.4 6.7 7 0 0 7 7 7 0 Leucine Rich repeat Ig_mannosidase PF17753.1 KIK43915.1 - 4e-11 42.5 0.0 1.1e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 KIK43915.1 - 6.9e-09 36.2 0.1 2.1e-08 34.7 0.1 1.9 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KIK43915.1 - 0.0072 17.0 0.1 0.018 15.7 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyoxalase PF00903.25 KIK43916.1 - 2.3e-20 73.1 0.0 3.2e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KIK43916.1 - 0.00029 21.1 0.0 0.00045 20.5 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.6 KIK43916.1 - 0.0094 16.0 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 CppA N-terminal Glyoxalase_6 PF18029.1 KIK43916.1 - 0.015 16.0 0.0 0.022 15.5 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KIK43916.1 - 0.051 13.7 0.0 0.06 13.5 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase-like domain Methyltransf_22 PF13383.6 KIK43917.1 - 3.7e-22 79.1 0.0 4.6e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KIK43917.1 - 1.4e-08 34.9 0.0 2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF1892 PF08987.10 KIK43917.1 - 0.11 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1892) Ribosomal_S2 PF00318.20 KIK43918.1 - 1.5e-29 102.8 0.1 3.8e-15 55.7 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KIK43918.1 - 2e-10 41.9 9.7 3.5e-10 41.1 9.7 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Glyco_hydro_18 PF00704.28 KIK43919.1 - 1.6e-59 202.2 2.6 1.9e-59 202.0 2.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GHL10 PF02638.15 KIK43919.1 - 0.0018 17.4 0.1 0.0038 16.4 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase-like 10 Glyco_transf_10 PF00852.19 KIK43919.1 - 0.085 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) C-term Pkinase PF00069.25 KIK43922.1 - 2.2e-69 233.8 0.0 2.9e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK43922.1 - 2.5e-37 128.6 0.0 3.6e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KIK43922.1 - 1.5e-16 60.5 0.0 3.2e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kdo PF06293.14 KIK43922.1 - 1.3e-07 31.2 0.1 2.5e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIK43922.1 - 1.1e-06 28.2 0.0 1.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Yop-YscD_cpl PF16697.5 KIK43922.1 - 8.7e-05 22.8 0.0 0.00028 21.1 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 KIK43922.1 - 0.0046 16.9 0.2 0.013 15.4 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF3421 PF11901.8 KIK43922.1 - 0.0048 16.9 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3421) Pkinase_fungal PF17667.1 KIK43922.1 - 0.0064 15.3 0.0 0.018 13.8 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase FHA_2 PF17913.1 KIK43922.1 - 0.0099 16.1 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Haspin_kinase PF12330.8 KIK43922.1 - 0.092 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain SKIP_SNW PF02731.15 KIK43925.1 - 0.049 13.3 0.1 0.059 13.0 0.1 1.0 1 0 0 1 1 1 0 SKIP/SNW domain Securin PF04856.13 KIK43926.1 - 2.8 7.9 8.8 8.2 6.3 8.8 1.9 1 1 0 1 1 1 0 Securin sister-chromatid separation inhibitor Pkinase PF00069.25 KIK43927.1 - 3.2e-29 102.1 0.0 6.2e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK43927.1 - 2.8e-21 76.0 0.0 5.8e-21 74.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK43927.1 - 0.031 14.2 0.0 0.088 12.7 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family PC-Esterase PF13839.6 KIK43930.1 - 3.7e-07 30.2 0.0 0.0055 16.5 0.0 2.3 2 0 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DUF4025 PF13217.6 KIK43932.1 - 0.13 12.1 0.1 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4025) Creatinase_N_2 PF16189.5 KIK43934.1 - 3.3e-43 147.6 0.1 9e-42 142.9 0.0 2.7 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KIK43934.1 - 5.1e-42 143.9 0.0 7.7e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KIK43934.1 - 5.3e-21 74.4 1.0 1.7e-20 72.8 1.0 2.0 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KIK43934.1 - 1.4e-16 61.4 0.0 1.3e-15 58.3 0.0 2.2 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain FTO_CTD PF12934.7 KIK43934.1 - 1.2 8.9 4.7 0.34 10.7 0.7 2.1 2 0 0 2 2 2 0 FTO C-terminal domain Vir_act_alpha_C PF10400.9 KIK43934.1 - 5 7.9 7.1 9.8 6.9 0.8 3.4 2 2 0 2 2 2 0 Virulence activator alpha C-term NOG1_N PF17835.1 KIK43935.1 - 5.3e-50 169.5 0.5 1.2e-49 168.4 0.5 1.6 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KIK43935.1 - 2.8e-27 94.4 1.1 8.7e-27 92.9 1.1 1.9 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 KIK43935.1 - 7.8e-27 92.8 0.0 1.8e-26 91.7 0.0 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KIK43935.1 - 2.6e-17 62.9 0.0 6.2e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIK43935.1 - 7.4e-10 38.6 0.0 1.7e-09 37.4 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KIK43935.1 - 0.0011 18.9 0.1 0.79 9.6 0.0 2.9 2 1 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KIK43935.1 - 0.0061 16.6 0.1 2 8.5 0.0 2.9 2 1 1 3 3 3 1 Dynamin family Sushi_2 PF09014.10 KIK43935.1 - 0.049 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain AIG1 PF04548.16 KIK43935.1 - 0.075 12.3 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AAA_16 PF13191.6 KIK43935.1 - 0.092 13.1 0.0 0.7 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Raf1_HTH PF18579.1 KIK43935.1 - 0.092 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain Pkinase PF00069.25 KIK43936.1 - 2.3e-37 128.8 0.0 3e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK43936.1 - 5.3e-33 114.4 0.0 6.7e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase G-alpha PF00503.20 KIK43938.1 - 9.4e-106 353.9 0.0 1.2e-105 353.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK43938.1 - 2.9e-08 33.4 0.1 6.2e-05 22.5 0.0 2.7 2 1 1 3 3 3 2 ADP-ribosylation factor family TniB PF05621.11 KIK43938.1 - 0.046 13.1 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 KIK43938.1 - 0.13 12.5 0.0 0.52 10.5 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KIK43938.1 - 0.14 11.5 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Lipoprotein_7 PF01540.16 KIK43938.1 - 0.23 10.7 0.6 0.54 9.5 0.0 1.7 2 0 0 2 2 2 0 Adhesin lipoprotein DUF2615 PF11027.8 KIK43939.1 - 0.083 13.0 0.0 0.26 11.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Macoilin PF09726.9 KIK43939.1 - 3 6.3 9.9 3.3 6.2 9.9 1.1 1 0 0 1 1 1 0 Macoilin family SAPS PF04499.15 KIK43939.1 - 3.2 6.4 8.7 3.7 6.2 8.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein tRNA-synt_2 PF00152.20 KIK43940.1 - 5.1e-76 255.8 0.0 6.5e-76 255.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIK43940.1 - 5.5e-11 42.3 0.0 1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KIK43940.1 - 3.3e-08 33.3 0.0 0.00031 20.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) IHABP4_N PF16174.5 KIK43940.1 - 0.33 11.6 6.9 0.52 10.9 2.4 2.1 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal IBR PF01485.21 KIK43941.1 - 1.1e-15 57.6 41.0 3e-09 37.0 16.7 3.8 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KIK43941.1 - 1.2e-05 25.0 2.4 1.2e-05 25.0 2.4 4.2 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK43941.1 - 0.0003 20.8 4.2 0.0003 20.8 4.2 3.9 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIK43941.1 - 0.0003 20.6 6.0 0.0003 20.6 6.0 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK43941.1 - 0.0052 16.6 2.4 0.0052 16.6 2.4 4.3 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK43941.1 - 0.015 15.3 5.9 0.015 15.3 5.9 3.9 3 1 0 3 3 3 0 zinc-RING finger domain zf-RING_2 PF13639.6 KIK43941.1 - 0.018 15.3 6.6 0.018 15.3 6.6 3.7 3 0 0 3 3 3 0 Ring finger domain zf-C3HC4_4 PF15227.6 KIK43941.1 - 0.018 15.2 3.4 0.018 15.2 3.4 4.3 3 1 1 4 4 4 0 zinc finger of C3HC4-type, RING Cellulase PF00150.18 KIK43942.1 - 0.0076 15.7 0.1 0.014 14.8 0.1 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PSCyt2 PF07583.11 KIK43942.1 - 0.054 13.4 0.0 0.082 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) Glyco_tranf_2_3 PF13641.6 KIK43943.1 - 1.1e-30 107.3 0.0 1.7e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIK43943.1 - 1.2e-09 38.2 0.0 1.9e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KIK43943.1 - 1.3e-07 31.2 0.0 7.5e-07 28.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 KIK43943.1 - 0.0071 16.3 8.7 0.016 15.2 8.7 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 MAGI_u5 PF16666.5 KIK43946.1 - 1.3 9.2 5.3 21 5.3 0.0 2.3 2 0 0 2 2 2 0 Unstructured region on MAGI HET PF06985.11 KIK43947.1 - 4.3e-11 43.4 3.0 6.7e-09 36.2 0.2 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) WD40 PF00400.32 KIK43948.1 - 1.2e-57 190.5 22.7 3.4e-08 34.0 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK43948.1 - 6e-25 87.4 2.1 3.9e-06 27.1 0.0 6.7 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK43948.1 - 4.4e-12 45.6 1.7 0.021 13.8 0.0 6.1 2 1 5 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK43948.1 - 1.5e-07 31.1 0.0 0.028 13.7 0.0 4.5 4 1 1 5 5 5 2 WD40-like domain Nup160 PF11715.8 KIK43948.1 - 1.1e-06 27.6 8.5 0.02 13.6 0.3 3.8 1 1 3 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.12 KIK43948.1 - 2.7e-06 27.2 3.0 3.3 7.8 0.0 5.8 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK43948.1 - 0.00046 19.6 1.1 21 4.3 0.0 4.7 1 1 4 5 5 5 0 Neuroblastoma-amplified sequence, N terminal HWE_HK PF07536.14 KIK43948.1 - 0.021 15.5 0.1 0.044 14.5 0.1 1.5 1 0 0 1 1 1 0 HWE histidine kinase Coatomer_WDAD PF04053.14 KIK43948.1 - 0.022 13.8 0.0 0.059 12.4 0.0 1.6 1 1 0 1 1 1 0 Coatomer WD associated region Frtz PF11768.8 KIK43948.1 - 0.051 11.9 0.0 15 3.7 0.0 3.4 2 1 2 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz Proteasome_A_N PF10584.9 KIK43948.1 - 0.072 12.8 4.1 9.3 6.0 0.6 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DUF5570 PF17731.1 KIK43948.1 - 0.11 12.6 5.0 0.27 11.3 1.0 3.3 3 2 1 4 4 4 0 Family of unknown function (DUF5570) FMO-like PF00743.19 KIK43949.1 - 1.2e-20 73.5 0.2 2.7e-18 65.7 0.2 2.9 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK43949.1 - 9e-18 64.6 0.0 2.7e-16 59.7 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK43949.1 - 1.7e-16 60.3 0.0 1.5e-07 31.0 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK43949.1 - 1.6e-14 53.8 0.9 3.3e-09 36.4 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KIK43949.1 - 4.7e-09 36.7 0.3 0.00018 22.0 0.1 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK43949.1 - 5.8e-05 23.2 0.0 0.0013 18.9 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIK43949.1 - 0.0001 21.2 0.2 0.0024 16.6 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KIK43949.1 - 0.0001 22.0 0.0 0.28 10.7 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KIK43949.1 - 0.0014 18.0 0.0 0.038 13.3 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KIK43949.1 - 0.0019 18.2 0.2 14 5.7 0.0 3.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KIK43949.1 - 0.0045 16.1 0.1 0.082 11.9 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK43949.1 - 0.0048 16.0 0.1 0.0099 15.0 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KIK43949.1 - 0.014 14.6 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KIK43949.1 - 0.018 14.1 0.1 0.16 11.0 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 KIK43949.1 - 0.021 15.2 0.0 9.2 6.8 0.0 2.6 3 0 0 3 3 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 KIK43949.1 - 0.052 13.4 0.1 4.7 7.0 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KIK43949.1 - 0.059 13.6 0.5 0.21 11.9 0.0 2.2 4 0 0 4 4 1 0 TrkA-N domain Shikimate_DH PF01488.20 KIK43949.1 - 0.087 12.9 0.1 4 7.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KIK43949.1 - 0.1 11.9 0.6 0.45 9.8 0.6 2.1 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KIK43949.1 - 0.14 11.4 0.2 0.43 9.8 0.0 1.8 2 0 0 2 2 2 0 Thi4 family IBR PF01485.21 KIK43952.1 - 0.002 18.3 3.0 0.0031 17.7 3.0 1.3 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain FOXP-CC PF16159.5 KIK43952.1 - 0.038 14.6 0.9 0.038 14.6 0.9 1.9 2 1 0 2 2 2 0 FOXP coiled-coil domain Zn_ribbon_recom PF13408.6 KIK43952.1 - 0.11 13.0 1.4 0.2 12.2 1.4 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2H2_4 PF13894.6 KIK43952.1 - 4.6 8.4 5.5 2.3 9.3 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK43953.1 - 0.03 14.8 5.0 0.3 11.6 0.5 2.8 2 0 0 2 2 2 0 Zinc-finger double domain Med19 PF10278.9 KIK43954.1 - 0.002 18.1 27.1 0.002 18.1 27.1 2.7 3 0 0 3 3 3 1 Mediator of RNA pol II transcription subunit 19 DUF1965 PF09248.10 KIK43954.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) Sacchrp_dh_NADP PF03435.18 KIK43955.1 - 8.1e-16 58.5 0.0 1.2e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KIK43955.1 - 0.00012 22.0 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KIK43955.1 - 0.00036 21.0 0.0 0.001 19.5 0.0 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KIK43955.1 - 0.0017 18.3 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK43955.1 - 0.0019 17.7 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KIK43955.1 - 0.0025 17.3 0.0 0.0043 16.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 KIK43955.1 - 0.028 13.4 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KIK43955.1 - 0.08 12.5 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family zf-C2H2 PF00096.26 KIK43956.1 - 1.3e-05 25.4 0.6 1.3e-05 25.4 0.6 2.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK43956.1 - 0.00095 19.8 4.7 0.007 17.1 0.5 2.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 KIK43956.1 - 0.0032 17.8 0.4 0.013 15.8 0.1 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KIK43956.1 - 0.0042 17.7 1.2 0.19 12.4 0.6 2.5 2 0 0 2 2 2 1 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KIK43956.1 - 0.015 15.3 1.1 0.076 13.0 0.3 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK43956.1 - 0.02 15.2 0.2 0.061 13.6 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TetR_C_15 PF17918.1 KIK43956.1 - 0.043 14.6 0.1 0.08 13.7 0.1 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain zf-H2C2_2 PF13465.6 KIK43956.1 - 0.059 13.8 1.2 0.44 11.1 0.1 2.7 2 1 0 2 2 2 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 KIK43956.1 - 0.12 12.8 0.7 0.27 11.6 0.3 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 KIK43956.1 - 0.31 11.1 3.6 0.94 9.6 1.2 2.7 2 1 1 3 3 3 0 BED zinc finger DUF4651 PF15513.6 KIK43959.1 - 0.034 14.0 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) zf-C2H2_4 PF13894.6 KIK43960.1 - 0.0011 19.6 9.0 0.11 13.4 1.0 3.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK43960.1 - 0.011 16.1 6.0 0.37 11.3 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 KIK43960.1 - 0.018 15.0 2.0 0.04 13.9 2.0 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KIK43960.1 - 7.8 6.4 8.7 0.39 10.5 0.3 2.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIK43960.1 - 8 7.1 10.6 1.9 9.1 1.0 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 KIK43961.1 - 0.057 14.0 12.4 0.22 12.2 8.6 3.0 2 1 0 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 KIK43961.1 - 0.1 12.4 0.3 0.1 12.4 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KIK43961.1 - 3.1 8.9 0.0 3.1 8.9 0.0 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger Metallophos PF00149.28 KIK43962.1 - 4.4e-15 56.7 3.4 9.1e-15 55.7 3.4 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 KIK43962.1 - 0.0056 16.9 0.0 0.017 15.4 0.0 1.8 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain UNC119_bdg PF15435.6 KIK43964.1 - 0.12 11.9 0.9 0.19 11.2 0.5 1.5 1 1 1 2 2 2 0 UNC119-binding protein C5orf30 homologue Clat_adaptor_s PF01217.20 KIK43966.1 - 5e-17 62.2 0.0 7.3e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain FCH PF00611.23 KIK43967.1 - 1.1e-15 57.6 0.6 3.2e-15 56.2 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KIK43967.1 - 2.5e-09 36.6 0.3 4.6e-09 35.7 0.3 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK43967.1 - 4.6e-08 32.8 0.1 8.4e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIK43967.1 - 3.2e-05 23.5 0.0 6.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Fascin PF06268.13 KIK43968.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Fascin domain Glyco_hydro_16 PF00722.21 KIK43969.1 - 6.1e-06 25.8 0.0 1.2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 zf-FPG_IleRS PF06827.14 KIK43970.1 - 0.0027 17.5 0.4 0.0045 16.8 0.4 1.4 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS zf-RRPl_C4 PF17026.5 KIK43970.1 - 0.0057 16.7 0.1 0.0067 16.5 0.1 1.2 1 0 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type Zn-ribbon_8 PF09723.10 KIK43970.1 - 0.015 15.4 3.5 0.023 14.8 3.5 1.3 1 0 0 1 1 1 0 Zinc ribbon domain HypA PF01155.19 KIK43970.1 - 0.023 14.7 0.4 0.026 14.5 0.4 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DpnI PF06044.12 KIK43970.1 - 0.03 13.9 0.3 0.03 13.9 0.3 1.1 1 0 0 1 1 1 0 Dam-replacing family NOB1_Zn_bind PF08772.11 KIK43970.1 - 0.032 14.4 1.0 0.046 13.9 1.0 1.3 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-UDP PF14569.6 KIK43970.1 - 0.039 14.1 0.9 0.057 13.5 0.9 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger zinc_ribbon_4 PF13717.6 KIK43970.1 - 0.074 13.0 7.7 0.97 9.4 0.1 2.6 3 0 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KIK43970.1 - 0.087 12.8 2.5 2.7 8.0 0.1 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF4379 PF14311.6 KIK43970.1 - 0.093 13.1 1.0 0.15 12.5 1.0 1.4 1 0 0 1 1 1 0 Probable Zinc-ribbon domain RNHCP PF12647.7 KIK43970.1 - 0.17 11.9 2.6 0.19 11.7 2.5 1.3 1 1 0 1 1 1 0 RNHCP domain zinc_ribbon_9 PF14369.6 KIK43970.1 - 0.39 11.0 5.8 0.24 11.7 3.2 1.9 2 1 0 2 2 2 0 zinc-ribbon C1_4 PF07975.12 KIK43970.1 - 0.56 10.5 5.7 4.4 7.6 5.4 2.1 1 1 0 1 1 1 0 TFIIH C1-like domain Cys_rich_KTR PF14205.6 KIK43970.1 - 0.58 10.0 0.0 0.58 10.0 0.0 2.2 1 1 1 2 2 2 0 Cysteine-rich KTR zf-ribbon_3 PF13248.6 KIK43970.1 - 0.8 9.2 5.5 0.53 9.8 0.6 2.3 1 1 0 2 2 2 0 zinc-ribbon domain zf-DNL PF05180.12 KIK43970.1 - 2.7 8.0 6.2 13 5.8 6.2 1.9 1 1 0 1 1 1 0 DNL zinc finger DUF2781 PF10914.8 KIK43971.1 - 0.37 11.2 9.4 0.75 10.2 0.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2781) Ank_2 PF12796.7 KIK43973.1 - 3.2e-15 56.5 0.0 1.7e-10 41.4 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIK43973.1 - 1.3e-10 41.3 0.2 0.0013 19.0 0.0 3.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KIK43973.1 - 9.8e-10 38.8 0.4 0.001 19.6 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK43973.1 - 8.1e-09 35.0 0.0 0.019 15.5 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KIK43973.1 - 1.1e-07 32.0 0.4 0.02 15.3 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Hydrophobin PF01185.18 KIK43976.1 - 0.0023 18.6 16.3 0.0038 17.8 16.3 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Metallophos PF00149.28 KIK43978.1 - 3.3e-14 53.9 0.6 5.5e-14 53.2 0.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase p450 PF00067.22 KIK43979.1 - 6.8e-69 232.8 0.0 8.4e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FLYWCH PF04500.16 KIK43980.1 - 0.15 12.2 0.4 0.16 12.1 0.4 1.3 1 0 0 1 1 1 0 FLYWCH zinc finger domain p450 PF00067.22 KIK43981.1 - 5.9e-58 196.7 0.0 1.2e-41 143.0 0.0 2.9 2 1 0 2 2 2 2 Cytochrome P450 DUF2062 PF09835.9 KIK43982.1 - 0.061 13.2 0.4 0.061 13.2 0.4 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) RNase_H PF00075.24 KIK43988.1 - 1.4e-07 31.8 0.1 1.5e-07 31.7 0.1 1.2 1 0 0 1 1 1 1 RNase H ARD PF03079.14 KIK43989.1 - 9e-44 149.4 0.1 1e-43 149.2 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KIK43989.1 - 1.9e-09 37.1 0.2 4.3e-09 36.0 0.2 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KIK43989.1 - 2.1e-06 27.7 0.2 2.7e-06 27.3 0.2 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 KIK43989.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_1 PF00190.22 KIK43989.1 - 0.019 14.6 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_8 PF13621.6 KIK43989.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.5 1 1 0 1 1 1 0 Cupin-like domain AMP-binding PF00501.28 KIK43991.1 - 1.9e-82 277.2 0.0 2.3e-82 276.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK43991.1 - 6.2e-12 46.3 0.8 2e-11 44.7 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 2-Hacid_dh_C PF02826.19 KIK43992.1 - 1.9e-51 173.9 0.0 2.7e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIK43992.1 - 2.1e-15 56.6 0.0 2.6e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIK43992.1 - 0.00045 20.4 0.0 0.00087 19.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KIK43992.1 - 0.0098 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 KIK43992.1 - 0.039 13.2 0.1 0.082 12.2 0.0 1.6 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2263 PF10021.9 KIK43994.1 - 1.1e-26 94.0 0.0 2e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) SE PF08491.10 KIK43995.1 - 5.4e-88 294.6 0.0 7.2e-88 294.2 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KIK43995.1 - 2.1e-12 47.0 0.0 1.1e-11 44.6 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIK43995.1 - 1.1e-11 44.9 0.1 8.2e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIK43995.1 - 8e-07 28.3 0.7 0.028 13.3 0.1 3.0 3 0 0 3 3 3 2 Tryptophan halogenase FAD_binding_2 PF00890.24 KIK43995.1 - 1.2e-06 27.9 1.7 0.0029 16.7 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KIK43995.1 - 0.00018 20.9 1.1 0.0007 18.9 1.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIK43995.1 - 0.00031 19.9 0.3 0.061 12.4 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KIK43995.1 - 0.00034 20.8 0.3 0.00079 19.6 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK43995.1 - 0.0047 16.0 0.3 0.17 10.9 0.2 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein Sacchrp_dh_NADP PF03435.18 KIK43995.1 - 0.0074 16.5 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GMC_oxred_N PF00732.19 KIK43995.1 - 0.037 13.4 0.5 0.92 8.8 0.1 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Thi4 PF01946.17 KIK43995.1 - 0.079 12.2 0.1 0.21 10.8 0.1 1.6 2 0 0 2 2 2 0 Thi4 family DHHA2 PF02833.14 KIK43996.1 - 1.6e-28 99.7 0.1 3e-28 98.8 0.1 1.5 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KIK43996.1 - 4.7e-14 52.4 0.0 1.8e-13 50.6 0.0 1.9 2 0 0 2 2 2 1 DHH family MFS_1 PF07690.16 KIK44001.1 - 6.6e-34 117.4 33.3 1e-33 116.8 33.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily CopD PF05425.13 KIK44001.1 - 0.0024 18.2 0.2 0.0024 18.2 0.2 3.7 3 1 1 4 4 4 1 Copper resistance protein D bZIP_1 PF00170.21 KIK44003.1 - 2e-07 31.0 15.3 2.7e-06 27.4 7.6 3.0 2 1 1 3 3 3 2 bZIP transcription factor Tropomyosin PF00261.20 KIK44003.1 - 0.009 15.4 5.9 0.014 14.8 5.9 1.3 1 0 0 1 1 1 1 Tropomyosin YkyA PF10368.9 KIK44003.1 - 0.095 12.4 1.4 0.17 11.5 1.4 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF5094 PF17015.5 KIK44003.1 - 0.21 11.7 0.4 0.36 10.9 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) APC_N_CC PF16689.5 KIK44003.1 - 0.3 11.2 0.2 0.3 11.2 0.2 1.9 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain MOZ_SAS PF01853.18 KIK44005.1 - 4.1e-80 267.7 0.3 6e-80 267.1 0.3 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KIK44005.1 - 2e-22 78.5 1.3 4.2e-22 77.5 1.3 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KIK44005.1 - 3.4e-18 65.3 0.0 9e-18 63.9 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain HTH_Mga PF08280.11 KIK44005.1 - 0.00082 19.4 1.0 0.0017 18.3 1.0 1.5 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain Acetyltransf_7 PF13508.7 KIK44005.1 - 0.005 17.2 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK44005.1 - 0.02 15.1 0.0 0.049 13.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family HTH_11 PF08279.12 KIK44005.1 - 0.088 12.8 0.1 0.25 11.3 0.1 1.8 1 0 0 1 1 1 0 HTH domain zf-C2H2_4 PF13894.6 KIK44005.1 - 0.61 11.1 4.4 0.36 11.8 1.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger LAG1-DNAbind PF09271.11 KIK44007.1 - 1.3e-49 168.8 0.0 2.1e-49 168.0 0.0 1.4 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 KIK44007.1 - 9.2e-20 71.4 0.0 3.1e-18 66.5 0.0 2.6 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain zf-ribbon_3 PF13248.6 KIK44008.1 - 0.19 11.2 0.9 0.34 10.4 0.3 1.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-GRF PF06839.12 KIK44011.1 - 1.9e-09 37.4 0.2 3.4e-09 36.6 0.2 1.4 1 0 0 1 1 1 1 GRF zinc finger Cgr1 PF03879.14 KIK44011.1 - 0.051 13.9 4.4 0.13 12.7 4.4 1.6 1 0 0 1 1 1 0 Cgr1 family FAM76 PF16046.5 KIK44011.1 - 0.074 12.4 1.7 0.15 11.3 1.7 1.5 1 0 0 1 1 1 0 FAM76 protein APG6_N PF17675.1 KIK44011.1 - 0.3 11.6 9.2 0.59 10.7 9.2 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 KIK44011.1 - 0.34 11.2 6.0 0.9 9.8 6.0 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Cnn_1N PF07989.11 KIK44011.1 - 0.42 10.8 8.2 0.93 9.7 8.2 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 YabA PF06156.13 KIK44011.1 - 1.5 9.5 6.6 9.8 6.9 6.6 2.2 1 1 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 KIK44011.1 - 3.2 8.2 10.7 0.51 10.8 3.7 2.3 1 1 1 2 2 2 0 Cell division protein ZapB PAC4 PF16093.5 KIK44012.1 - 5.9e-21 74.4 0.0 8.8e-21 73.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 zf-RING_13 PF17977.1 KIK44012.1 - 0.031 14.4 0.1 0.049 13.8 0.1 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Pkinase PF00069.25 KIK44013.1 - 5.2e-51 173.5 0.1 9.1e-51 172.7 0.1 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK44013.1 - 2.2e-21 76.3 0.0 3.5e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK44013.1 - 0.00017 21.6 0.1 0.00017 21.6 0.1 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK44013.1 - 0.0028 17.3 0.0 0.0069 16.0 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KIK44013.1 - 0.098 12.2 1.1 0.17 11.5 0.3 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase 2-oxoacid_dh PF00198.23 KIK44014.1 - 1.1e-81 273.8 0.1 1.4e-81 273.4 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KIK44014.1 - 3.4e-19 68.4 1.8 6.8e-19 67.5 1.8 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KIK44014.1 - 2.5e-06 27.2 0.1 1.8e-05 24.4 0.1 2.2 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KIK44014.1 - 9.7e-05 23.0 0.3 0.065 13.9 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.19 KIK44014.1 - 0.00068 19.5 0.2 0.0018 18.2 0.2 1.7 1 0 0 1 1 1 1 Glycine cleavage H-protein DUF3614 PF12267.8 KIK44014.1 - 0.015 15.8 1.1 0.39 11.2 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3614) eIF-3_zeta PF05091.12 KIK44014.1 - 0.049 12.6 2.3 1.6 7.6 0.6 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Asp PF00026.23 KIK44015.1 - 1.5e-61 208.6 1.6 1.9e-61 208.2 1.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK44015.1 - 6.7e-11 42.7 1.8 1.3e-05 25.5 1.5 3.3 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK44015.1 - 0.00032 21.3 0.0 1.4 9.6 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KIK44015.1 - 0.0085 16.6 0.0 1.2 9.7 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease PTPLA PF04387.14 KIK44017.1 - 7.5e-53 178.6 6.7 7.5e-53 178.6 6.7 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA PapB PF03333.13 KIK44018.1 - 0.00037 20.5 0.0 0.00055 19.9 0.0 1.2 1 0 0 1 1 1 1 Adhesin biosynthesis transcription regulatory protein Asp PF00026.23 KIK44020.1 - 3e-70 237.1 2.8 3.7e-70 236.9 2.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK44020.1 - 2.8e-10 40.7 1.7 0.00081 19.7 0.2 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK44020.1 - 0.0031 18.1 0.4 2.4 8.9 0.1 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KIK44020.1 - 0.096 12.5 0.2 0.91 9.3 0.0 2.4 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal Pkinase PF00069.25 KIK44022.1 - 2.2e-51 174.8 0.0 3.9e-51 173.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK44022.1 - 3.5e-31 108.4 0.0 2e-30 106.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK44022.1 - 1.1e-06 28.2 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIK44022.1 - 0.027 13.4 0.0 0.052 12.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain BAG PF02179.16 KIK44023.1 - 1.5e-17 63.8 0.0 2.7e-17 63.0 0.0 1.4 1 1 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KIK44023.1 - 1.9e-07 30.7 0.0 3.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF3618 PF12277.8 KIK44023.1 - 0.032 14.5 0.5 0.032 14.5 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) DUF5090 PF17009.5 KIK44024.1 - 0.53 10.2 3.0 0.65 9.9 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) ADK PF00406.22 KIK44027.1 - 9.6e-46 155.6 0.1 1.7e-45 154.8 0.1 1.4 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KIK44027.1 - 2.1e-33 115.6 0.0 3.1e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIK44027.1 - 5.3e-08 33.5 0.0 7.9e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIK44027.1 - 1.9e-05 24.9 0.1 0.065 13.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain Thymidylate_kin PF02223.17 KIK44027.1 - 2e-05 24.3 0.6 0.021 14.5 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase Ploopntkinase3 PF18751.1 KIK44027.1 - 0.016 15.1 0.0 0.04 13.8 0.0 1.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 dNK PF01712.19 KIK44027.1 - 0.091 12.6 0.1 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 Deoxynucleoside kinase Viral_helicase1 PF01443.18 KIK44027.1 - 0.12 12.1 0.0 2.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase WD40 PF00400.32 KIK44029.1 - 5.1e-28 96.8 16.1 4.9e-07 30.4 0.0 7.8 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK44029.1 - 8.4e-09 35.6 0.2 1.3 9.3 0.1 5.2 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK44029.1 - 0.0022 17.0 0.3 2.5 7.0 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK44029.1 - 0.081 12.8 0.2 2.7 7.8 0.0 2.6 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KIK44029.1 - 0.11 11.2 0.0 1.6 7.4 0.0 2.3 2 1 0 2 2 2 0 Nup133 N terminal like 2-Hacid_dh_C PF02826.19 KIK44031.1 - 1.4e-45 154.8 0.0 2.1e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIK44031.1 - 2.5e-18 66.0 0.0 3.3e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIK44031.1 - 0.00013 22.1 0.0 0.00044 20.5 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KIK44031.1 - 0.041 14.0 0.0 0.16 12.0 0.0 2.0 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1816 PF08846.10 KIK44031.1 - 0.088 12.8 0.2 0.26 11.3 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) NAD_binding_7 PF13241.6 KIK44031.1 - 0.14 12.6 0.1 1.1 9.7 0.0 2.4 2 1 0 2 2 2 0 Putative NAD(P)-binding EXS PF03124.14 KIK44033.1 - 8.9e-104 347.4 9.1 1e-103 347.2 9.1 1.0 1 0 0 1 1 1 1 EXS family Anticodon_1 PF08264.13 KIK44033.1 - 0.022 14.7 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA zf-C2H2_jaz PF12171.8 KIK44034.1 - 3.8e-06 27.0 0.1 6.7e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIK44034.1 - 0.00046 20.5 0.3 0.00078 19.8 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 KIK44034.1 - 0.00057 19.9 0.6 0.002 18.1 0.6 2.0 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins PAXIP1_C PF15364.6 KIK44034.1 - 0.0041 17.4 2.8 0.0041 17.4 2.8 2.2 2 0 0 2 2 2 1 PAXIP1-associated-protein-1 C term PTIP binding protein zf-C2H2 PF00096.26 KIK44034.1 - 0.21 12.1 0.8 0.36 11.4 0.8 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type Orbi_VP6 PF01516.16 KIK44034.1 - 5.3 6.5 11.9 0.019 14.5 1.9 1.8 2 0 0 2 2 2 0 Orbivirus helicase VP6 Atg14 PF10186.9 KIK44034.1 - 8.6 5.3 14.4 4.8 6.2 3.8 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 tRNA-synt_1 PF00133.22 KIK44035.1 - 1.7e-215 716.9 0.0 2.2e-215 716.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KIK44035.1 - 1.6e-25 89.9 0.3 3.8e-25 88.6 0.2 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KIK44035.1 - 2.7e-12 46.1 0.4 3.5e-05 22.7 0.2 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) SWIB PF02201.18 KIK44035.1 - 0.024 14.5 0.6 0.74 9.7 0.1 2.6 2 0 0 2 2 2 0 SWIB/MDM2 domain tRNA-synt_1e PF01406.19 KIK44035.1 - 0.077 12.3 0.0 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain p450 PF00067.22 KIK44036.1 - 7.5e-12 44.7 0.0 9e-12 44.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Bromodomain PF00439.25 KIK44037.1 - 3.1e-23 81.6 0.1 5.9e-23 80.8 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KIK44037.1 - 0.00012 22.3 0.0 0.00023 21.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK44037.1 - 0.00067 19.6 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK44037.1 - 0.008 16.6 0.2 0.015 15.7 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pinin_SDK_N PF04697.13 KIK44037.1 - 0.034 14.8 3.9 0.066 13.9 3.9 1.4 1 0 0 1 1 1 0 pinin/SDK conserved region FR47 PF08445.10 KIK44037.1 - 0.16 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein CENP-B_dimeris PF09026.10 KIK44037.1 - 2.2 8.7 13.2 5.6 7.4 13.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.14 KIK44037.1 - 2.7 6.2 6.6 3.8 5.7 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.11 KIK44037.1 - 4 7.5 7.0 6.1 6.9 6.3 1.6 1 1 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 KIK44037.1 - 9 4.3 7.7 14 3.6 7.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi K_oxygenase PF13434.6 KIK44038.1 - 8.7e-85 284.9 0.0 9.1e-83 278.2 0.0 2.1 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KIK44038.1 - 1.3e-06 27.9 0.0 2.1e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK44038.1 - 7.8e-05 22.1 0.0 0.0012 18.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK44038.1 - 0.0086 16.1 0.1 4.3 7.3 0.0 3.1 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 KIK44038.1 - 0.014 15.9 0.0 8.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 KIK44041.1 - 9.3e-43 146.5 0.0 1.3e-42 146.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK44041.1 - 1.3e-26 93.4 0.0 2e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MRP-L20 PF12824.7 KIK44041.1 - 0.0067 16.6 2.1 0.012 15.8 1.1 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 APH PF01636.23 KIK44041.1 - 0.053 13.4 2.3 1.7 8.5 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK44041.1 - 0.095 12.0 0.0 0.23 10.7 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Homeodomain PF00046.29 KIK44042.1 - 6.8e-17 61.1 1.7 1.2e-16 60.3 1.7 1.4 1 0 0 1 1 1 1 Homeodomain zf-TRAF PF02176.18 KIK44043.1 - 1e-12 48.5 20.0 8.3e-07 29.6 5.2 4.4 1 1 4 5 5 5 4 TRAF-type zinc finger zf-TRAF_2 PF15965.5 KIK44043.1 - 2e-07 31.4 22.8 0.00029 21.2 1.0 4.0 1 1 2 3 3 3 3 TRAF-like zinc-finger zf-C3HC4_2 PF13923.6 KIK44043.1 - 5.1e-07 29.4 13.1 5.1e-07 29.4 13.1 3.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK44043.1 - 6.8e-06 26.0 12.3 6.8e-06 26.0 12.3 3.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIK44043.1 - 1.2e-05 25.5 12.3 1.2e-05 25.5 12.3 3.7 3 1 2 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.25 KIK44043.1 - 5e-05 23.1 13.7 5e-05 23.1 13.7 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KIK44043.1 - 0.00042 20.1 8.2 0.00042 20.1 8.2 3.2 3 1 1 4 4 4 1 Zinc-finger of the MIZ type in Nse subunit zf-ACC PF17848.1 KIK44043.1 - 0.00079 19.4 0.7 0.033 14.3 0.0 2.7 2 0 0 2 2 2 1 Acetyl-coA carboxylase zinc finger domain zf-C3HC4_3 PF13920.6 KIK44043.1 - 0.0011 18.8 8.3 0.0011 18.8 8.3 3.1 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK44043.1 - 0.0047 16.8 11.5 0.0047 16.8 11.5 3.1 3 0 0 3 3 3 1 zinc-RING finger domain Sina PF03145.16 KIK44043.1 - 0.0081 16.1 17.1 1.7 8.6 4.0 3.8 1 1 3 4 4 4 3 Seven in absentia protein family zf_UBZ PF18439.1 KIK44043.1 - 1.3 8.7 8.4 25 4.6 0.0 3.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C3HC4_4 PF15227.6 KIK44043.1 - 9.3 6.5 18.8 0.38 11.0 9.9 3.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING AAA_16 PF13191.6 KIK44045.1 - 0.00014 22.3 0.0 0.00019 21.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK44045.1 - 0.00056 19.9 0.0 0.00083 19.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KIK44045.1 - 0.0012 18.1 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 KIK44045.1 - 0.02 15.3 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KIK44045.1 - 0.025 14.7 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KIK44045.1 - 0.051 13.5 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Torsin PF06309.11 KIK44045.1 - 0.056 13.5 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_18 PF13238.6 KIK44045.1 - 0.13 12.8 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Steroid_dh PF02544.16 KIK44046.1 - 1.7e-28 99.5 5.4 3.8e-27 95.1 5.4 2.6 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KIK44046.1 - 1.3e-07 31.3 0.6 3.4e-07 30.0 0.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Rer1 PF03248.13 KIK44047.1 - 3.5e-79 264.5 2.8 4.1e-79 264.3 2.8 1.0 1 0 0 1 1 1 1 Rer1 family DUF4191 PF13829.6 KIK44047.1 - 0.32 10.3 1.0 17 4.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF2208 PF09973.9 KIK44047.1 - 2.5 7.7 6.3 0.26 10.9 1.2 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) KAP_NTPase PF07693.14 KIK44048.1 - 0.011 15.0 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.6 KIK44048.1 - 0.017 15.5 0.0 0.038 14.4 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 KIK44048.1 - 0.031 14.3 0.0 0.34 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2791 PF10923.8 KIK44048.1 - 0.072 11.9 0.0 0.39 9.5 0.0 1.8 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) Zeta_toxin PF06414.12 KIK44048.1 - 0.073 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.21 KIK44048.1 - 0.086 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cyclin_N PF00134.23 KIK44051.1 - 6.8e-12 45.2 0.0 9.6e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIK44051.1 - 1.4e-05 25.6 0.0 1.9e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin CCDC-167 PF15188.6 KIK44054.1 - 0.046 14.1 0.6 0.062 13.7 0.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 zf-CCCH_2 PF14608.6 KIK44058.1 - 9.8e-16 57.6 32.8 6.8e-06 26.4 1.5 4.3 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger FoP_duplication PF13865.6 KIK44058.1 - 0.41 11.2 7.4 1.3 9.6 7.4 1.8 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Fungal_lectin PF07938.12 KIK44059.1 - 1.9e-15 57.0 0.4 3.7e-15 56.1 0.4 1.5 1 1 0 1 1 1 1 Fungal fucose-specific lectin Lenti_VIF_2 PF07401.12 KIK44059.1 - 0.037 13.4 0.1 0.13 11.6 0.1 1.7 1 1 1 2 2 2 0 Bovine Lentivirus VIF protein DUF4241 PF14025.6 KIK44061.1 - 0.099 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) CPSase_L_D2 PF02786.17 KIK44062.1 - 1.9e-106 354.3 0.0 2.4e-83 278.8 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KIK44062.1 - 3.1e-39 134.1 0.3 7.1e-39 132.9 0.3 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KIK44062.1 - 3.3e-16 59.3 0.0 7.9e-07 28.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KIK44062.1 - 9.3e-12 44.9 0.0 5.2e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KIK44062.1 - 1.6e-10 40.9 0.0 0.001 18.8 0.0 2.8 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 KIK44062.1 - 2.3e-06 27.3 0.0 0.0057 16.1 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 KIK44062.1 - 0.00017 21.7 0.0 0.006 16.6 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain DAO PF01266.24 KIK44063.1 - 8e-41 140.8 0.2 1e-40 140.4 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIK44063.1 - 5.8e-09 36.4 0.6 0.0051 17.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK44063.1 - 3.3e-08 33.1 0.1 6.2e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK44063.1 - 4.7e-08 32.6 0.1 0.0044 16.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK44063.1 - 3.5e-07 30.3 0.0 9.5e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIK44063.1 - 2.1e-06 26.7 0.1 0.0028 16.4 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Amino_oxidase PF01593.24 KIK44063.1 - 6.4e-06 25.7 0.1 0.047 13.0 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KIK44063.1 - 2.8e-05 24.2 0.1 0.041 13.9 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KIK44063.1 - 0.00026 20.3 0.0 0.021 14.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KIK44063.1 - 0.0009 19.3 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KIK44063.1 - 0.0013 18.1 0.1 0.029 13.6 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain RcpC PF16976.5 KIK44063.1 - 0.004 17.2 0.0 0.007 16.4 0.0 1.3 1 0 0 1 1 1 1 Flp pilus assembly protein RcpC/CpaB GIDA PF01134.22 KIK44063.1 - 0.0063 15.6 0.2 0.42 9.6 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 KIK44063.1 - 0.0089 14.9 0.1 0.31 9.9 0.0 2.0 2 0 0 2 2 2 1 Tryptophan halogenase ApbA PF02558.16 KIK44063.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KIK44063.1 - 0.011 16.0 0.0 0.054 13.8 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Glu_dehyd_C PF16912.5 KIK44063.1 - 0.02 14.4 0.0 0.043 13.3 0.0 1.5 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Thi4 PF01946.17 KIK44063.1 - 0.026 13.8 0.1 0.2 10.8 0.0 2.0 2 0 0 2 2 2 0 Thi4 family GMC_oxred_N PF00732.19 KIK44063.1 - 0.032 13.6 0.5 1.2 8.5 0.1 2.4 2 1 0 2 2 2 0 GMC oxidoreductase NAD_binding_7 PF13241.6 KIK44063.1 - 0.033 14.6 0.0 0.085 13.3 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 KIK44063.1 - 0.047 13.6 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KIK44063.1 - 0.14 12.5 0.0 0.6 10.4 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Lyase_aromatic PF00221.19 KIK44068.1 - 4e-140 467.6 1.9 6.4e-140 466.9 1.9 1.3 1 0 0 1 1 1 1 Aromatic amino acid lyase CLN3 PF02487.17 KIK44068.1 - 0.012 14.7 1.1 0.02 14.0 1.1 1.2 1 0 0 1 1 1 0 CLN3 protein Gar1 PF04410.14 KIK44069.1 - 0.2 11.4 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region Fcf1 PF04900.12 KIK44072.1 - 9.8e-38 128.5 1.9 1.9e-37 127.6 1.9 1.5 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KIK44072.1 - 9.8e-12 45.2 0.3 4.2e-11 43.2 0.0 1.9 2 0 0 2 2 2 1 PIN like domain MFS_1 PF07690.16 KIK44076.1 - 3e-29 102.0 33.2 3e-29 102.0 33.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily COX14 PF14880.6 KIK44079.1 - 0.0002 21.2 4.6 0.00043 20.1 4.6 1.6 1 1 0 1 1 1 1 Cytochrome oxidase c assembly YqhR PF11085.8 KIK44079.1 - 0.13 12.2 0.1 0.19 11.6 0.0 1.3 1 1 0 1 1 1 0 Conserved membrane protein YqhR SNF2_N PF00176.23 KIK44080.1 - 2.1e-62 210.9 0.3 3.3e-62 210.2 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK44080.1 - 9e-18 64.6 0.0 2e-16 60.3 0.1 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK44080.1 - 4.8e-10 39.7 0.0 2.8e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Pkinase PF00069.25 KIK44081.1 - 4.7e-69 232.7 0.0 5.7e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK44081.1 - 3.2e-37 128.2 0.0 4.2e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIK44081.1 - 0.057 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF829 PF05705.14 KIK44082.1 - 6.7e-40 137.5 0.0 8.2e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF2920 PF11144.8 KIK44082.1 - 0.18 10.9 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Homeodomain PF00046.29 KIK44083.1 - 2.5e-05 24.0 0.3 0.034 14.0 0.1 2.5 2 0 0 2 2 2 2 Homeodomain DnaJ PF00226.31 KIK44084.1 - 1.1e-14 54.3 0.0 1.7e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain ER_lumen_recept PF00810.18 KIK44085.1 - 7.3e-57 192.3 9.0 1.1e-56 191.7 9.0 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KIK44085.1 - 0.083 12.7 12.3 0.42 10.4 0.1 4.2 5 0 0 5 5 5 0 PQ loop repeat TRI5 PF06330.11 KIK44086.1 - 4.8e-16 58.6 0.2 6.2e-16 58.2 0.2 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Lectin_leg-like PF03388.13 KIK44087.1 - 6.4e-66 222.0 0.0 8.2e-66 221.6 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 KIK44087.1 - 0.00016 21.3 0.0 0.0049 16.4 0.0 2.1 1 1 0 1 1 1 1 Legume lectin domain HEAT_EZ PF13513.6 KIK44088.1 - 1.1e-31 108.9 17.7 8.5e-15 54.9 0.0 10.0 9 1 0 9 9 9 4 HEAT-like repeat HEAT PF02985.22 KIK44088.1 - 1e-17 62.7 15.1 3.6e-05 23.7 0.0 9.4 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 KIK44088.1 - 1.9e-16 60.2 0.2 6.3e-05 23.3 0.0 6.9 5 3 2 8 8 8 3 HEAT repeats Arm PF00514.23 KIK44088.1 - 6.1e-09 35.6 0.7 0.18 11.9 0.0 6.0 7 0 0 7 7 5 2 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 KIK44088.1 - 1.4e-08 35.2 0.0 0.0087 16.6 0.0 3.4 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KIK44088.1 - 2e-07 31.2 0.0 0.17 11.9 0.0 4.3 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KIK44088.1 - 1.1e-05 24.2 0.1 0.73 8.3 0.1 3.9 5 0 0 5 5 5 2 Adaptin N terminal region DUF3437 PF11919.8 KIK44088.1 - 1.5e-05 24.8 0.4 0.058 13.3 0.0 4.8 5 0 0 5 5 5 1 Domain of unknown function (DUF3437) Cnd3 PF12719.7 KIK44088.1 - 0.00097 18.4 0.0 4.8 6.3 0.0 3.6 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain IBN_N PF03810.19 KIK44088.1 - 0.0026 17.6 0.1 0.014 15.3 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain RTP1_C1 PF10363.9 KIK44088.1 - 0.0037 17.4 0.1 0.052 13.7 0.0 3.0 5 0 0 5 5 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Ecm29 PF13001.7 KIK44088.1 - 0.0062 15.3 0.0 2.9 6.5 0.0 2.7 2 0 0 2 2 2 2 Proteasome stabiliser Tti2 PF10521.9 KIK44088.1 - 0.045 13.3 0.1 14 5.1 0.0 3.9 2 2 2 4 4 4 0 Tti2 family DUF5372 PF17342.2 KIK44088.1 - 0.052 14.0 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5372) Cohesin_HEAT PF12765.7 KIK44088.1 - 0.1 12.9 0.0 8.2 6.8 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Pro-kuma_activ PF09286.11 KIK44089.1 - 1.1e-45 155.5 0.9 2.8e-45 154.1 0.4 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK44089.1 - 0.00046 19.5 1.6 0.00089 18.6 1.6 1.4 1 0 0 1 1 1 1 Subtilase family RNase_T PF00929.24 KIK44090.1 - 2.6e-22 80.1 0.1 8e-21 75.3 0.1 2.0 1 1 0 1 1 1 1 Exonuclease DUF4838 PF16126.5 KIK44090.1 - 0.091 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4838) Pkinase PF00069.25 KIK44091.1 - 1.5e-36 126.1 0.0 1.8e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK44091.1 - 2.7e-34 118.6 0.0 3.1e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK44091.1 - 1.1e-06 28.2 0.0 1.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KIK44091.1 - 0.0061 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KIK44091.1 - 0.0095 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK44091.1 - 0.011 15.7 0.1 0.033 14.1 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1917 PF08939.10 KIK44092.1 - 1.2e-23 84.4 0.1 1.2e-23 84.4 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1917) CCSAP PF15748.5 KIK44092.1 - 5 7.2 20.2 1.2 9.3 1.4 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated RVT_1 PF00078.27 KIK44094.1 - 1.2e-06 28.2 0.0 3.8e-06 26.6 0.0 1.8 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF445 PF04286.12 KIK44094.1 - 0.054 13.3 0.0 0.059 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) RVT_1 PF00078.27 KIK44095.1 - 0.00093 18.8 0.2 0.0018 17.8 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 KIK44096.1 - 1e-68 231.6 0.0 1.5e-68 231.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK44096.1 - 1.6e-37 129.2 0.0 2.3e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK44096.1 - 3.7e-07 29.8 0.0 6.4e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.19 KIK44096.1 - 2.2e-05 24.2 0.0 4.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 KIK44096.1 - 0.01 14.8 0.3 0.01 14.8 0.3 1.7 2 0 0 2 2 2 0 Haspin like kinase domain RIO1 PF01163.22 KIK44096.1 - 0.018 14.6 0.1 0.04 13.5 0.1 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KIK44096.1 - 0.068 13.1 1.1 0.1 12.5 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family HNH_2 PF13391.6 KIK44097.1 - 1.8e-09 37.6 0.0 4.6e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease MAP7 PF05672.11 KIK44098.1 - 0.43 10.3 24.6 0.57 9.9 24.6 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Roughex PF06020.11 KIK44099.1 - 0.095 11.8 0.6 0.15 11.1 0.0 1.6 2 1 0 2 2 2 0 Drosophila roughex protein zf-TRM13_CCCH PF11722.8 KIK44102.1 - 0.036 13.8 0.1 0.06 13.1 0.1 1.4 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein WD40 PF00400.32 KIK44104.1 - 1e-26 92.6 10.0 9.6e-10 38.9 0.9 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK44104.1 - 2.6e-17 62.9 0.2 0.00031 21.0 0.1 4.2 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK44104.1 - 1.9e-06 27.1 0.0 0.019 13.9 0.0 3.5 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK44104.1 - 9.3e-06 25.2 0.1 0.0015 17.9 0.0 2.5 1 1 1 2 2 2 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KIK44104.1 - 2.5e-05 24.1 0.2 6.2 6.9 0.0 4.5 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat PQQ PF01011.21 KIK44104.1 - 2.7e-05 23.9 0.1 4.6 7.3 0.0 4.5 4 1 1 5 5 5 1 PQQ enzyme repeat Nup160 PF11715.8 KIK44104.1 - 2.7e-05 23.0 0.3 1.8 7.1 0.0 3.9 2 1 1 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK44104.1 - 0.00079 19.4 0.1 0.053 13.4 0.1 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 KIK44104.1 - 0.0015 18.9 0.6 0.82 10.2 0.7 3.4 3 1 0 3 3 3 1 PQQ-like domain WD40_like PF17005.5 KIK44104.1 - 0.0032 16.9 0.0 0.0054 16.1 0.0 1.3 1 1 0 1 1 1 1 WD40-like domain DPPIV_N PF00930.21 KIK44104.1 - 0.017 13.9 0.0 2.6 6.7 0.0 2.9 3 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ_2 PF13360.6 KIK44104.1 - 0.03 13.9 2.0 0.1 12.2 2.1 2.0 1 1 0 1 1 1 0 PQQ-like domain RAB3GAP2_N PF14655.6 KIK44104.1 - 0.035 13.4 0.0 0.64 9.2 0.0 2.5 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nucleoporin_N PF08801.11 KIK44104.1 - 0.049 12.4 0.2 2 7.1 0.0 2.5 1 1 1 2 2 2 0 Nup133 N terminal like Hira PF07569.11 KIK44104.1 - 0.099 12.3 0.1 6.7 6.4 0.0 3.2 3 1 1 4 4 4 0 TUP1-like enhancer of split DUF3283 PF11686.8 KIK44104.1 - 0.16 11.9 0.0 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3283) DUF3845 PF12956.7 KIK44104.1 - 0.18 11.2 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure Proteasome_A_N PF10584.9 KIK44104.1 - 2.4 7.9 4.6 70 3.2 0.1 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature MFS_1 PF07690.16 KIK44106.1 - 1.2e-30 106.7 34.8 1.7e-30 106.2 34.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK44106.1 - 5.5e-05 21.8 3.4 0.0001 20.9 1.3 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) C_GCAxxG_C_C PF09719.10 KIK44106.1 - 0.78 10.0 4.2 0.84 9.9 2.1 1.9 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) CHAT PF12770.7 KIK44107.1 - 5.3e-08 32.6 0.1 6e-08 32.4 0.1 1.0 1 0 0 1 1 1 1 CHAT domain zf-HC5HC2H_2 PF13832.6 KIK44107.1 - 0.015 15.4 0.1 0.015 15.4 0.1 1.2 1 0 0 1 1 1 0 PHD-zinc-finger like domain WD40 PF00400.32 KIK44108.1 - 8.9e-29 99.1 25.3 1.4e-08 35.3 1.3 7.6 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK44108.1 - 5e-16 58.8 3.9 0.0032 17.7 0.1 5.6 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK44108.1 - 1.2e-06 27.5 4.0 0.017 13.8 0.1 4.0 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK44108.1 - 9.6e-05 21.5 0.1 0.26 10.2 0.0 3.1 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 KIK44108.1 - 0.0011 19.4 0.3 2.8 8.6 0.0 4.2 3 0 0 3 3 3 1 PQQ-like domain Nucleoporin_N PF08801.11 KIK44108.1 - 0.0055 15.5 0.0 3 6.5 0.0 2.9 1 1 1 3 3 3 2 Nup133 N terminal like WD40_like PF17005.5 KIK44108.1 - 0.0071 15.7 0.0 0.023 14.0 0.0 1.9 1 1 0 1 1 1 1 WD40-like domain PQQ PF01011.21 KIK44108.1 - 0.056 13.4 0.0 37 4.5 0.0 4.1 4 0 0 4 4 4 0 PQQ enzyme repeat Integrase_H2C2 PF17921.1 KIK44111.1 - 7e-09 35.7 2.0 1.7e-08 34.4 2.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KIK44111.1 - 0.034 14.4 0.2 0.063 13.5 0.2 1.4 1 0 0 1 1 1 0 H2C2 zinc finger SKN1 PF03935.15 KIK44112.1 - 7.8e-180 598.5 0.4 9.1e-180 598.3 0.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) HEM4 PF02602.15 KIK44113.1 - 1.2e-27 96.7 0.0 1.5e-27 96.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Mito_carr PF00153.27 KIK44115.1 - 5.6e-63 208.9 3.6 2.3e-21 75.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4574 PF15141.6 KIK44115.1 - 0.075 12.9 0.0 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Serine_protease PF18405.1 KIK44115.1 - 3.7 6.6 5.0 6.7 5.8 0.1 3.3 2 2 1 4 4 4 0 Gammaproteobacterial serine protease Peptidase_C41 PF05417.11 KIK44118.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Hepatitis E cysteine protease Histone PF00125.24 KIK44120.1 - 5e-19 68.9 0.0 6e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KIK44120.1 - 3.1e-10 39.6 0.1 3.1e-10 39.6 0.1 2.4 3 0 0 3 3 3 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KIK44120.1 - 0.0091 16.3 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Rtt106 PF08512.12 KIK44121.1 - 3.7e-17 62.5 0.0 1.1e-16 61.0 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KIK44121.1 - 0.00042 20.3 0.0 0.00072 19.6 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PPP4R2 PF09184.11 KIK44121.1 - 3.8 7.0 12.2 7.7 6.0 12.2 1.5 1 0 0 1 1 1 0 PPP4R2 Transposase_21 PF02992.14 KIK44122.1 - 3.8e-06 26.3 0.0 7.2e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 Spc7 PF08317.11 KIK44124.1 - 0.0029 16.5 1.9 0.0083 15.0 1.9 1.7 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF16 PF01519.16 KIK44124.1 - 0.0043 17.5 2.1 0.016 15.7 1.8 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF16 CENP-F_leu_zip PF10473.9 KIK44124.1 - 0.0055 16.7 2.2 0.0096 16.0 2.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 KIK44124.1 - 0.025 14.7 1.2 0.051 13.7 1.2 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Tup_N PF08581.10 KIK44124.1 - 0.028 14.7 1.2 0.07 13.4 1.2 1.7 1 0 0 1 1 1 0 Tup N-terminal SlyX PF04102.12 KIK44124.1 - 0.074 13.7 4.1 0.22 12.2 4.1 1.8 1 0 0 1 1 1 0 SlyX DUF1664 PF07889.12 KIK44124.1 - 0.15 12.1 1.4 0.3 11.1 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 KIK44124.1 - 0.17 12.1 1.9 0.37 11.1 1.9 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) ZapB PF06005.12 KIK44124.1 - 0.21 12.0 4.6 0.64 10.5 4.6 1.8 1 1 0 1 1 1 0 Cell division protein ZapB WD40 PF00400.32 KIK44126.1 - 9e-29 99.1 18.8 5.4e-09 36.5 1.2 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK44126.1 - 9.1e-18 64.3 0.4 0.00059 20.1 0.0 4.9 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK44126.1 - 2.7e-06 26.6 0.1 0.0038 16.2 0.0 3.7 1 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK44126.1 - 0.00021 20.1 0.3 0.21 10.2 0.0 3.1 2 1 0 2 2 2 2 Nucleoporin Nup120/160 PD40 PF07676.12 KIK44126.1 - 0.0004 20.2 0.1 2.8 8.0 0.0 4.2 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK44126.1 - 0.0041 16.5 1.3 0.02 14.2 0.1 2.5 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.14 KIK44126.1 - 0.0097 15.0 0.3 0.2 10.7 0.2 2.0 1 1 1 2 2 2 1 Coatomer WD associated region PQQ_3 PF13570.6 KIK44126.1 - 0.013 15.9 3.7 7.6 7.2 1.7 4.2 2 2 2 4 4 4 0 PQQ-like domain PQQ PF01011.21 KIK44126.1 - 0.035 14.0 4.6 5.9 7.0 0.0 4.8 6 0 0 6 6 6 0 PQQ enzyme repeat DUF2963 PF11178.8 KIK44126.1 - 0.15 11.8 0.0 5.7 6.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2963) SAM_PNT PF02198.16 KIK44128.1 - 0.072 13.1 0.0 0.089 12.8 0.0 1.1 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain MFS_1 PF07690.16 KIK44131.1 - 7.5e-12 44.8 23.7 1.1e-11 44.3 23.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK44131.1 - 9e-11 41.3 7.4 1.4e-10 40.6 7.3 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter Prefoldin PF02996.17 KIK44132.1 - 2.4e-25 88.8 0.7 1.5e-23 83.0 0.7 2.2 1 1 0 1 1 1 1 Prefoldin subunit Syntaxin-6_N PF09177.11 KIK44132.1 - 1 9.9 4.9 92 3.7 5.2 2.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal RRM_1 PF00076.22 KIK44133.1 - 4.5e-72 237.8 0.4 3.8e-17 61.9 0.0 6.2 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIK44133.1 - 3.6e-09 36.4 0.0 0.00022 21.0 0.0 4.6 5 0 0 5 5 5 2 Occluded RNA-recognition motif RRM_3 PF08777.11 KIK44133.1 - 8.4e-08 32.2 0.3 0.22 11.6 0.0 4.7 5 0 0 5 5 5 2 RNA binding motif Nup35_RRM_2 PF14605.6 KIK44133.1 - 2.9e-07 30.4 0.7 0.33 11.0 0.0 4.3 5 0 0 5 5 5 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KIK44133.1 - 5e-05 23.6 2.5 13 6.0 0.0 6.7 6 3 3 9 9 9 1 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 KIK44133.1 - 0.013 15.6 0.0 9.2 6.5 0.0 3.6 4 0 0 4 4 4 0 RNA recognition motif RRM_2 PF04059.12 KIK44133.1 - 0.043 14.0 0.0 1e+02 3.2 0.0 3.9 4 0 0 4 4 4 0 RNA recognition motif 2 SET_assoc PF11767.8 KIK44133.1 - 0.065 12.9 0.0 52 3.6 0.0 4.4 5 0 0 5 5 5 0 Histone lysine methyltransferase SET associated HTH_CodY PF08222.11 KIK44133.1 - 0.13 11.8 0.1 0.4 10.3 0.1 1.8 1 0 0 1 1 1 0 CodY helix-turn-helix domain Arm-DNA-bind_4 PF14657.6 KIK44133.1 - 0.16 11.7 2.5 4.2 7.2 0.4 3.3 3 0 0 3 3 3 0 Arm DNA-binding domain Nucleo_P87 PF07267.11 KIK44133.1 - 5.6 5.7 6.2 8.5 5.1 6.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Aldo_ket_red PF00248.21 KIK44137.1 - 2.7e-34 118.7 0.0 1.8e-33 116.0 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family HyaE PF07449.11 KIK44137.1 - 0.16 11.9 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE SPC25 PF06703.11 KIK44139.1 - 1.4 8.7 6.9 0.17 11.7 2.4 1.8 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) WD40 PF00400.32 KIK44140.1 - 9.8e-45 149.7 17.8 1e-06 29.4 0.0 8.8 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK44140.1 - 6.8e-17 61.6 1.5 2.9e-06 27.5 0.0 5.3 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 KIK44140.1 - 4.5e-10 40.0 5.2 4.3e-08 33.6 0.9 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ge1_WD40 PF16529.5 KIK44140.1 - 1.5e-07 30.7 1.3 0.18 10.7 0.0 4.8 2 1 4 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK44140.1 - 0.0003 20.6 0.0 12 5.9 0.0 5.1 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 KIK44140.1 - 0.0011 18.8 0.8 1.1 8.9 0.1 2.7 2 0 0 2 2 2 2 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 KIK44140.1 - 0.015 14.0 6.6 0.26 9.9 0.2 3.9 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KIK44140.1 - 0.047 12.2 0.1 4.2 5.8 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Sugar_tr PF00083.24 KIK44141.1 - 1.5e-108 363.5 30.3 1.8e-108 363.4 30.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK44141.1 - 1.4e-20 73.5 38.6 1.4e-20 73.5 38.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_1 PF00561.20 KIK44142.1 - 6e-18 65.4 0.1 2.2e-17 63.5 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK44142.1 - 1.1e-14 55.6 0.0 2.6e-14 54.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KIK44142.1 - 1.3e-08 34.9 0.1 2.4e-07 30.7 0.1 2.1 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KIK44142.1 - 4.5e-08 32.6 0.0 5.8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KIK44142.1 - 1.5e-07 31.8 0.0 1.7e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.14 KIK44142.1 - 0.0002 21.0 0.0 0.00034 20.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase PF07224.11 KIK44142.1 - 0.0031 16.6 0.0 0.0055 15.8 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 KIK44142.1 - 0.0042 16.0 0.1 0.0069 15.3 0.1 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.20 KIK44142.1 - 0.016 14.9 0.1 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 Putative esterase DUF2048 PF09752.9 KIK44142.1 - 0.016 14.3 0.2 0.67 9.0 0.0 2.2 2 1 0 2 2 2 0 Abhydrolase domain containing 18 Palm_thioest PF02089.15 KIK44142.1 - 0.059 13.2 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF915 PF06028.11 KIK44142.1 - 0.1 11.9 0.0 9.2 5.5 0.1 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) MIP PF00230.20 KIK44143.1 - 1.5e-46 158.9 17.5 1.8e-46 158.7 17.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein TrbC PF04956.13 KIK44143.1 - 0.81 9.9 12.1 0.27 11.5 8.4 2.0 1 1 1 2 2 2 0 TrbC/VIRB2 family HSBP1 PF06825.12 KIK44144.1 - 8.6e-18 63.9 4.2 1.2e-17 63.5 4.2 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 KNTase_C PF07827.11 KIK44144.1 - 0.017 15.0 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 KNTase C-terminal domain Baculo_PEP_C PF04513.12 KIK44144.1 - 0.046 13.8 0.1 0.06 13.4 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3517 PF12030.8 KIK44144.1 - 0.12 11.3 0.0 0.15 11.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) FdhE PF04216.12 KIK44144.1 - 0.13 12.2 0.1 0.14 12.0 0.1 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Terpene_synth_C PF03936.16 KIK44145.1 - 1.7e-07 30.9 0.0 2.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Ank_5 PF13857.6 KIK44146.1 - 7.1e-15 54.9 0.2 7.6e-07 29.3 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KIK44146.1 - 1e-14 54.7 0.0 2.1e-10 40.9 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK44146.1 - 7.2e-14 50.5 0.2 0.002 18.5 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KIK44146.1 - 1.1e-13 50.9 0.3 0.004 17.5 0.1 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 KIK44146.1 - 1.5e-13 51.1 0.0 3.3e-12 46.8 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) MG4 PF17789.1 KIK44146.1 - 0.13 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Macroglobulin domain MG4 Ank_4 PF13637.6 KIK44147.1 - 7.1e-14 52.0 0.0 4.9e-07 30.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK44147.1 - 1.2e-10 41.8 0.0 1.6e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIK44147.1 - 7.3e-10 38.9 0.1 1.4e-08 34.8 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KIK44147.1 - 1e-08 34.7 0.0 6.5e-07 29.2 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KIK44147.1 - 1.6e-08 34.7 0.0 5.6e-08 32.9 0.0 1.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) zf-C2H2 PF00096.26 KIK44150.1 - 4.5e-07 30.0 9.9 0.00059 20.2 1.5 3.9 2 1 1 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK44150.1 - 2.7e-05 24.6 9.5 0.0046 17.7 0.5 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KIK44150.1 - 0.00081 19.3 8.0 0.001 19.0 1.3 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK44150.1 - 0.0026 18.0 2.7 0.081 13.2 0.3 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KIK44150.1 - 0.026 14.4 2.7 0.19 11.7 0.4 2.6 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 KIK44150.1 - 0.14 12.0 5.0 5.1 7.0 0.2 3.5 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KIK44150.1 - 0.16 12.5 4.7 3.6 8.2 0.1 3.6 3 1 0 3 3 3 0 Zinc-finger double domain zf-Di19 PF05605.12 KIK44150.1 - 0.3 11.4 5.6 0.17 12.2 2.1 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KIK44150.1 - 0.63 9.9 6.3 2.3 8.1 0.3 3.5 2 1 1 3 3 3 0 zinc-finger C2H2-type Tfb2 PF03849.14 KIK44151.1 - 2.7e-137 457.5 0.0 3.2e-137 457.3 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KIK44151.1 - 2.6e-25 88.6 0.2 5.2e-25 87.6 0.2 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KIK44151.1 - 0.0045 17.1 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GRIP PF01465.20 KIK44151.1 - 0.015 15.2 0.3 0.042 13.8 0.3 1.8 1 0 0 1 1 1 0 GRIP domain DUF2249 PF10006.9 KIK44151.1 - 0.18 11.7 0.2 0.47 10.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) zf-RING_5 PF14634.6 KIK44156.1 - 0.016 15.2 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain CENP-W PF15510.6 KIK44157.1 - 0.067 13.4 0.2 0.25 11.6 0.2 1.9 1 0 0 1 1 1 0 CENP-W protein MFS_1 PF07690.16 KIK44159.1 - 2e-34 119.1 24.2 3e-34 118.5 24.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KIK44161.1 - 3.4e-35 121.6 28.1 5.7e-35 120.9 28.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily YrhC PF14143.6 KIK44161.1 - 1.6 8.9 5.3 2.9 8.1 0.1 3.7 4 0 0 4 4 4 0 YrhC-like protein FeoB_associated PF12669.7 KIK44161.1 - 3.4 8.2 4.6 4.9 7.6 0.1 3.3 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein He_PIG_assoc PF10632.9 KIK44163.1 - 0.016 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase F-box-like PF12937.7 KIK44164.1 - 1.5e-06 27.9 0.2 1.5e-06 27.9 0.2 2.2 2 0 0 2 2 2 1 F-box-like ATG16 PF08614.11 KIK44164.1 - 0.058 13.6 3.5 0.088 13.0 3.5 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) F-box-like PF12937.7 KIK44165.1 - 2.7e-10 40.0 1.7 7.3e-10 38.6 1.7 1.8 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 KIK44166.1 - 2.2e-39 135.4 54.3 7.8e-33 113.8 28.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK44166.1 - 1.5e-11 43.8 21.3 2.5e-11 43.1 21.3 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KIK44166.1 - 0.002 16.6 4.3 0.0025 16.3 0.5 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TMEM100 PF16311.5 KIK44167.1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 100 DcpS_C PF11969.8 KIK44168.1 - 6.1e-19 68.6 0.3 9.8e-19 67.9 0.3 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KIK44168.1 - 3.1e-07 31.0 5.5 1.4e-06 29.0 5.5 1.9 1 1 0 1 1 1 1 HIT domain UCH PF00443.29 KIK44169.1 - 1.2e-51 175.6 0.1 1.6e-51 175.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIK44169.1 - 3.1e-21 76.3 1.5 3.1e-21 76.3 1.5 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KIK44169.1 - 5.1e-14 52.4 8.3 5.1e-14 52.4 8.3 2.3 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein TF_Zn_Ribbon PF08271.12 KIK44169.1 - 0.48 10.0 10.0 5.3 6.6 0.1 3.6 3 0 0 3 3 3 0 TFIIB zinc-binding YL1 PF05764.13 KIK44170.1 - 0.0081 16.3 5.7 0.0094 16.1 5.7 1.1 1 0 0 1 1 1 1 YL1 nuclear protein SDA1 PF05285.12 KIK44170.1 - 0.034 13.6 5.8 0.035 13.5 5.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KIK44170.1 - 2 6.5 8.7 2.6 6.2 8.7 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KIK44170.1 - 2.3 6.4 7.8 2.9 6.1 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Thg1 PF04446.12 KIK44171.1 - 2.1e-48 163.4 0.1 3.4e-48 162.8 0.1 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KIK44171.1 - 3.5e-46 156.3 0.1 7.8e-46 155.2 0.0 1.6 2 0 0 2 2 2 1 Thg1 C terminal domain Forkhead PF00250.18 KIK44173.1 - 4.3e-28 97.4 0.1 6.4e-28 96.8 0.1 1.3 1 0 0 1 1 1 1 Forkhead domain WD40 PF00400.32 KIK44174.1 - 2.5e-18 66.1 6.9 1.8e-07 31.7 1.2 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK44174.1 - 3.3e-09 36.9 0.1 0.0032 17.7 0.0 4.2 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK44174.1 - 5.5e-05 23.0 0.8 3.1 7.9 0.0 4.2 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK44174.1 - 0.0017 17.4 0.0 0.3 10.0 0.0 2.8 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK44174.1 - 0.051 12.2 0.6 2.7 6.5 0.2 2.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KIK44174.1 - 0.59 10.7 2.3 3.7 8.2 0.4 2.9 3 0 0 3 3 3 0 PQQ-like domain Amidase PF01425.21 KIK44178.1 - 2.8e-103 346.3 0.0 4.4e-103 345.7 0.0 1.3 1 1 0 1 1 1 1 Amidase LRR_4 PF12799.7 KIK44179.1 - 2.1e-06 28.0 1.4 0.0075 16.7 0.2 3.3 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KIK44179.1 - 0.00013 21.7 0.2 1.5 9.1 0.0 3.5 4 0 0 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.6 KIK44179.1 - 0.0036 17.0 2.9 0.86 9.4 0.6 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_9 PF14580.6 KIK44179.1 - 0.0057 16.2 0.5 0.072 12.6 0.1 2.1 1 1 1 2 2 2 1 Leucine-rich repeat RabGAP-TBC PF00566.18 KIK44182.1 - 9.2e-49 166.0 0.0 1.6e-48 165.2 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain COX6B PF02297.17 KIK44183.1 - 4.5e-22 78.1 3.2 5.8e-22 77.7 3.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb TPR_2 PF07719.17 KIK44186.1 - 1.1e-12 47.0 10.0 0.00047 20.1 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIK44186.1 - 1.6e-12 46.7 7.6 0.002 17.9 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIK44186.1 - 2.5e-12 46.3 4.4 1.1e-06 28.2 0.5 3.3 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.6 KIK44186.1 - 4.3e-08 33.7 10.0 4.8e-07 30.3 1.7 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK44186.1 - 1e-07 32.1 5.2 0.021 15.6 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK44186.1 - 2.2e-06 28.1 3.0 3.8e-05 24.1 0.3 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK44186.1 - 3.5e-05 23.5 3.4 0.27 11.3 0.3 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK44186.1 - 3.9e-05 23.9 10.6 0.0015 18.8 2.5 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK44186.1 - 8.1e-05 22.5 4.5 0.089 13.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIK44186.1 - 0.0019 18.2 2.5 2.2 8.4 0.1 3.4 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KIK44186.1 - 0.0038 17.0 5.2 2 8.4 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KIK44186.1 - 0.029 13.8 0.1 0.078 12.4 0.1 1.7 1 0 0 1 1 1 0 SHNi-TPR ANAPC3 PF12895.7 KIK44186.1 - 0.046 13.9 1.0 0.12 12.7 1.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KIK44186.1 - 0.047 12.9 2.3 0.31 10.2 1.5 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TRADD_N PF09034.10 KIK44186.1 - 0.15 12.1 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 TRADD, N-terminal domain DBB PF14545.6 KIK44186.1 - 0.17 11.8 0.0 0.58 10.1 0.0 1.9 2 0 0 2 2 2 0 Dof, BCAP, and BANK (DBB) motif, TPR_6 PF13174.6 KIK44186.1 - 0.25 12.1 4.0 3.1 8.6 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 KIK44187.1 - 7.3e-21 74.5 37.6 9.2e-13 47.8 21.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK44187.1 - 2.3e-14 53.2 16.9 1.4e-13 50.5 16.9 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Arrestin_N PF00339.29 KIK44188.1 - 4.4e-06 26.8 0.0 1.6e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain CDC45 PF02724.14 KIK44188.1 - 0.32 9.2 13.3 0.46 8.7 13.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Cyclin_N PF00134.23 KIK44194.1 - 5e-44 149.1 0.2 8.8e-44 148.3 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KIK44194.1 - 6.4e-27 94.0 0.0 1.2e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain APG6_N PF17675.1 KIK44195.1 - 0.0072 16.9 1.5 0.0072 16.9 1.5 3.6 2 1 1 3 3 3 1 Apg6 coiled-coil region SP_C-Propep PF08999.10 KIK44195.1 - 0.012 15.4 2.5 2.2 8.1 0.4 2.5 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide MCU PF04678.13 KIK44195.1 - 0.2 11.7 0.1 0.2 11.7 0.1 2.5 1 1 1 2 2 2 0 Mitochondrial calcium uniporter Csm1_N PF18504.1 KIK44195.1 - 0.34 11.3 19.4 0.036 14.4 1.8 4.3 3 2 0 3 3 3 0 Csm1 N-terminal domain ATG16 PF08614.11 KIK44195.1 - 4 7.6 22.7 0.15 12.2 0.3 2.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 KIK44195.1 - 6.6 7.1 18.9 12 6.2 11.1 2.2 2 0 0 2 2 2 0 Fez1 CENP-H PF05837.12 KIK44195.1 - 9.8 6.6 23.5 6 7.3 9.4 3.3 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Zn_ribbon_17 PF17120.5 KIK44196.1 - 9e-05 22.0 10.8 9e-05 22.0 10.8 2.9 2 1 1 3 3 3 2 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 KIK44196.1 - 0.0096 16.0 6.7 0.012 15.7 5.7 1.7 1 1 0 1 1 1 1 KIAA1045 RING finger PHD_4 PF16866.5 KIK44196.1 - 0.26 11.4 8.3 1.5 9.0 8.3 2.3 1 1 0 1 1 1 0 PHD-finger zf-RING_9 PF13901.6 KIK44196.1 - 0.32 10.9 7.2 0.51 10.3 7.2 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon DUF5323 PF17257.2 KIK44197.1 - 0.025 14.4 1.6 0.025 14.4 1.6 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF5323) DUF1289 PF06945.13 KIK44197.1 - 1.2 9.0 4.3 0.39 10.6 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) WD40 PF00400.32 KIK44198.1 - 6.5e-05 23.6 15.8 0.015 16.2 2.2 5.5 4 1 0 4 4 4 3 WD domain, G-beta repeat MFS_1 PF07690.16 KIK44199.1 - 9.2e-19 67.6 56.1 6.5e-09 35.2 28.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM251 PF15190.6 KIK44199.1 - 0.038 13.9 1.4 0.088 12.8 1.4 1.6 1 0 0 1 1 1 0 Transmembrane protein 251 WD40 PF00400.32 KIK44200.1 - 2.4e-24 85.1 3.0 1.8e-07 31.7 0.2 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK44200.1 - 1.9e-08 34.5 0.0 0.014 15.7 0.0 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK44200.1 - 0.0038 16.2 0.0 0.098 11.6 0.1 2.3 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK44200.1 - 0.0054 15.4 0.1 0.49 9.0 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Aldo_ket_red PF00248.21 KIK44201.1 - 3.9e-75 252.8 0.0 4.5e-75 252.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cactin_mid PF10312.9 KIK44206.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Conserved mid region of cactin RPN1_RPN2_N PF17781.1 KIK44207.1 - 8.5e-111 370.2 0.0 1.4e-110 369.5 0.0 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KIK44207.1 - 2.2e-30 104.4 0.1 6.5e-30 103.0 0.1 1.9 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KIK44207.1 - 9.4e-22 76.3 16.8 0.00013 22.3 0.3 7.9 7 0 0 7 7 7 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KIK44207.1 - 7.9e-05 23.0 0.3 1.3 9.4 0.0 3.6 3 0 0 3 3 3 2 HEAT repeats Spc7 PF08317.11 KIK44207.1 - 0.027 13.3 0.8 0.052 12.4 0.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Methyltr_RsmB-F PF01189.17 KIK44209.1 - 8.4e-38 130.0 0.0 3.5e-34 118.2 0.0 2.8 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KIK44209.1 - 0.0086 16.2 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF2621 PF11084.8 KIK44209.1 - 0.063 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) MMR_HSR1 PF01926.23 KIK44212.1 - 6e-12 45.7 0.0 9.6e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK44212.1 - 1e-09 38.0 0.0 1.3e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KIK44212.1 - 2.5e-05 24.2 0.0 5.1e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Roc PF08477.13 KIK44212.1 - 0.0013 18.9 0.2 0.0035 17.6 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KIK44212.1 - 0.0049 17.4 0.0 0.0092 16.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 KIK44212.1 - 0.0077 16.3 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Ras PF00071.22 KIK44212.1 - 0.02 14.5 0.1 0.032 13.9 0.1 1.3 1 0 0 1 1 1 0 Ras family AAA_16 PF13191.6 KIK44212.1 - 0.023 15.1 0.0 0.046 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 KIK44212.1 - 0.024 14.1 0.1 0.044 13.3 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF815 PF05673.13 KIK44212.1 - 0.056 12.6 0.1 0.091 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA PF00004.29 KIK44212.1 - 0.11 13.0 0.0 0.24 11.8 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KIK44213.1 - 1.2e-09 38.3 0.0 1.7e-09 37.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK44213.1 - 5.5e-05 22.6 0.0 7.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 KIK44213.1 - 9.3e-05 22.6 0.1 0.0019 18.4 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KIK44213.1 - 0.002 18.1 0.0 0.0062 16.5 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KIK44213.1 - 0.0023 18.0 0.2 0.0073 16.4 0.1 1.9 1 1 1 2 2 2 1 Dynamin family ABC_tran PF00005.27 KIK44213.1 - 0.0053 17.3 0.0 0.0076 16.8 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KIK44213.1 - 0.01 16.1 0.0 0.027 14.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK44213.1 - 0.019 15.4 0.0 0.043 14.2 0.0 1.7 2 0 0 2 2 2 0 RNA helicase Ras PF00071.22 KIK44213.1 - 0.051 13.2 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 Ras family AAA_28 PF13521.6 KIK44213.1 - 0.054 13.7 0.0 0.56 10.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_23 PF13476.6 KIK44213.1 - 0.13 12.7 0.1 0.33 11.4 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KIK44213.1 - 0.15 12.6 0.1 0.85 10.2 0.0 2.0 1 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIK44213.1 - 0.18 12.2 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KIK44214.1 - 3e-12 46.6 0.0 4.4e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK44214.1 - 9e-07 28.4 0.0 1.5e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIK44214.1 - 1.3e-06 28.6 0.4 0.0019 18.3 0.3 2.3 1 1 1 2 2 2 2 Dynamin family Ras PF00071.22 KIK44214.1 - 3e-06 26.9 0.1 4.5e-05 23.1 0.1 2.2 1 1 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 KIK44214.1 - 0.00014 21.8 0.5 0.00028 20.9 0.3 1.5 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 KIK44214.1 - 0.00021 21.5 0.1 0.0012 19.0 0.1 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KIK44214.1 - 0.00057 20.3 0.0 0.001 19.5 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 KIK44214.1 - 0.0012 18.4 0.2 0.0017 17.9 0.2 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 KIK44214.1 - 0.0016 19.0 0.1 0.0029 18.1 0.1 1.5 1 0 0 1 1 1 1 ABC transporter Septin PF00735.18 KIK44214.1 - 0.0059 15.9 0.1 0.0092 15.3 0.1 1.3 1 0 0 1 1 1 1 Septin AAA_22 PF13401.6 KIK44214.1 - 0.0061 16.8 0.2 0.019 15.2 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIK44214.1 - 0.032 14.0 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 KIK44214.1 - 0.039 13.9 0.2 0.16 11.9 0.0 2.0 3 0 0 3 3 3 0 NACHT domain AAA_33 PF13671.6 KIK44214.1 - 0.043 14.0 0.1 0.13 12.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain Arf PF00025.21 KIK44214.1 - 0.072 12.5 0.0 0.61 9.5 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.18 KIK44214.1 - 0.089 12.1 0.2 0.19 11.0 0.1 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Gtr1_RagA PF04670.12 KIK44214.1 - 0.096 12.0 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KIK44214.1 - 0.13 11.7 0.1 1.6 8.3 0.1 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF815 PF05673.13 KIK44214.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 KIK44214.1 - 0.15 12.5 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KIK44217.1 - 1.5e-25 89.5 0.2 1.7e-11 44.2 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AIG1 PF04548.16 KIK44217.1 - 3.1e-15 56.1 0.1 3.9e-08 32.9 0.0 2.3 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 KIK44217.1 - 3.7e-12 46.5 1.5 0.0001 22.3 0.7 2.8 3 0 0 3 3 2 2 RsgA GTPase ABC_tran PF00005.27 KIK44217.1 - 6.3e-10 39.7 0.1 0.00065 20.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter Roc PF08477.13 KIK44217.1 - 3.8e-09 36.8 1.6 0.0022 18.2 0.2 3.7 3 1 1 4 4 4 2 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KIK44217.1 - 1.2e-08 35.2 3.3 0.0028 17.7 0.0 3.4 3 0 0 3 3 3 2 Dynamin family Ras PF00071.22 KIK44217.1 - 1.3e-08 34.6 0.8 0.00011 21.8 0.4 3.4 2 1 0 2 2 2 2 Ras family AAA_16 PF13191.6 KIK44217.1 - 1.2e-07 32.3 0.1 0.0029 18.0 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KIK44217.1 - 2.5e-06 27.8 0.8 0.14 12.5 0.1 3.6 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KIK44217.1 - 6.4e-06 25.8 0.3 0.13 12.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain FeoB_N PF02421.18 KIK44217.1 - 1e-05 25.1 0.4 0.17 11.4 0.0 2.7 2 1 0 2 2 2 2 Ferrous iron transport protein B DUF815 PF05673.13 KIK44217.1 - 1.6e-05 24.2 0.1 0.084 12.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_23 PF13476.6 KIK44217.1 - 1.9e-05 25.3 0.0 0.0088 16.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KIK44217.1 - 9e-05 22.3 0.2 0.58 9.8 0.1 2.9 3 0 0 3 3 3 2 AAA domain AAA_13 PF13166.6 KIK44217.1 - 0.00012 20.9 0.1 0.14 10.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KIK44217.1 - 0.00018 21.3 0.2 0.46 10.2 0.0 2.8 3 0 0 3 3 3 2 IstB-like ATP binding protein RNA_helicase PF00910.22 KIK44217.1 - 0.00043 20.6 0.1 1.3 9.5 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Septin PF00735.18 KIK44217.1 - 0.00048 19.5 0.3 0.61 9.3 0.1 2.4 2 0 0 2 2 2 2 Septin Zeta_toxin PF06414.12 KIK44217.1 - 0.00076 18.8 0.1 0.77 9.0 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin Sigma54_activat PF00158.26 KIK44217.1 - 0.0012 18.6 0.1 0.34 10.6 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain IIGP PF05049.13 KIK44217.1 - 0.0014 17.8 1.5 0.13 11.3 0.2 2.3 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) DUF87 PF01935.17 KIK44217.1 - 0.0015 18.7 1.3 2.7 8.0 0.3 3.0 3 0 0 3 3 3 1 Helicase HerA, central domain Arf PF00025.21 KIK44217.1 - 0.0035 16.8 0.2 4 6.8 0.0 3.1 3 0 0 3 3 3 1 ADP-ribosylation factor family TsaE PF02367.17 KIK44217.1 - 0.0036 17.3 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KIK44217.1 - 0.0088 16.2 1.7 0.94 9.6 0.5 3.4 3 1 0 3 3 3 1 AAA domain TniB PF05621.11 KIK44217.1 - 0.011 15.2 0.0 2 7.8 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 KIK44217.1 - 0.013 15.0 0.3 4.1 6.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KIK44217.1 - 0.014 14.8 0.7 4.6 6.5 0.1 2.6 3 0 0 3 3 2 0 FtsK/SpoIIIE family KAP_NTPase PF07693.14 KIK44217.1 - 0.014 14.6 0.0 1.4 8.0 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain AAA_28 PF13521.6 KIK44217.1 - 0.018 15.3 0.3 4.9 7.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KIK44217.1 - 0.022 14.7 0.2 9.2 6.2 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 KIK44217.1 - 0.027 14.5 0.1 9.2 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Virul_Fac PF10139.9 KIK44217.1 - 0.03 12.5 0.4 2.2 6.4 0.1 2.1 2 0 0 2 2 2 0 Putative bacterial virulence factor AAA_18 PF13238.6 KIK44217.1 - 0.033 14.7 0.1 6.7 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KIK44217.1 - 0.041 14.3 0.1 12 6.3 0.1 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 KIK44217.1 - 0.042 12.8 0.3 5 5.9 0.0 3.0 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.21 KIK44217.1 - 0.065 12.6 0.1 6.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI G-alpha PF00503.20 KIK44217.1 - 0.074 12.2 0.1 6.9 5.7 0.0 2.7 2 1 0 2 2 2 0 G-protein alpha subunit DLIC PF05783.11 KIK44217.1 - 0.098 11.5 0.1 4.3 6.1 0.0 2.4 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) PduV-EutP PF10662.9 KIK44217.1 - 0.13 12.0 0.0 9.1 6.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.7 KIK44217.1 - 0.14 11.0 0.5 6.9 5.5 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain SRPRB PF09439.10 KIK44217.1 - 0.15 11.5 0.1 6.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit dNK PF01712.19 KIK44217.1 - 0.46 10.3 2.5 16 5.2 0.0 3.0 3 0 0 3 3 3 0 Deoxynucleoside kinase MMR_HSR1 PF01926.23 KIK44218.1 - 1.3e-11 44.5 0.0 2e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK44218.1 - 3e-07 30.0 0.0 3.6e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KIK44218.1 - 0.00018 21.5 0.0 0.00033 20.6 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Roc PF08477.13 KIK44218.1 - 0.00063 20.0 0.1 0.0028 17.9 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KIK44218.1 - 0.0015 19.1 0.1 0.0026 18.3 0.1 1.4 1 1 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 KIK44218.1 - 0.011 15.9 0.3 0.02 15.0 0.3 1.6 1 1 0 1 1 1 0 Dynamin family AAA_13 PF13166.6 KIK44218.1 - 0.032 12.9 0.1 0.036 12.7 0.1 1.1 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KIK44218.1 - 0.049 13.2 0.2 0.09 12.3 0.1 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B dNK PF01712.19 KIK44218.1 - 0.078 12.8 0.1 0.25 11.2 0.1 1.8 1 1 0 1 1 1 0 Deoxynucleoside kinase AAA_22 PF13401.6 KIK44218.1 - 0.08 13.2 0.1 0.22 11.8 0.0 1.7 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.13 KIK44218.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 KIK44220.1 - 2.1e-19 69.7 0.3 1.2e-08 35.0 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KIK44220.1 - 6.4e-11 42.9 0.1 0.00029 21.3 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIK44220.1 - 8.2e-11 42.1 1.7 0.00038 20.4 0.3 2.7 3 0 0 3 3 2 2 RsgA GTPase AIG1 PF04548.16 KIK44220.1 - 1.5e-10 40.8 2.5 1e-05 25.0 0.0 2.7 2 1 0 2 2 2 2 AIG1 family ABC_tran PF00005.27 KIK44220.1 - 5.2e-10 40.0 0.5 0.0013 19.2 0.3 2.7 2 1 0 2 2 2 2 ABC transporter Dynamin_N PF00350.23 KIK44220.1 - 2.1e-08 34.4 3.6 0.0015 18.6 0.1 2.5 2 1 0 2 2 2 2 Dynamin family Roc PF08477.13 KIK44220.1 - 5.7e-06 26.6 2.4 0.13 12.5 0.3 3.6 2 2 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KIK44220.1 - 7.1e-06 26.3 0.2 0.12 12.6 0.1 3.1 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KIK44220.1 - 1.6e-05 24.5 0.1 0.23 11.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF815 PF05673.13 KIK44220.1 - 1.8e-05 24.0 0.1 0.089 11.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Ras PF00071.22 KIK44220.1 - 2.6e-05 23.9 2.0 0.43 10.1 0.7 3.2 2 1 0 2 2 2 2 Ras family Zeta_toxin PF06414.12 KIK44220.1 - 7.2e-05 22.2 0.1 0.059 12.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_23 PF13476.6 KIK44220.1 - 0.0001 22.9 0.0 0.74 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KIK44220.1 - 0.00024 20.9 0.0 0.071 12.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KIK44220.1 - 0.00061 19.5 0.1 0.65 9.7 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain Septin PF00735.18 KIK44220.1 - 0.00074 18.9 0.2 0.6 9.3 0.1 2.4 2 0 0 2 2 2 2 Septin FeoB_N PF02421.18 KIK44220.1 - 0.00074 19.1 3.2 0.3 10.6 0.3 2.9 3 0 0 3 3 3 2 Ferrous iron transport protein B Arf PF00025.21 KIK44220.1 - 0.0014 18.1 0.1 0.18 11.2 0.0 3.0 2 1 1 3 3 3 1 ADP-ribosylation factor family TniB PF05621.11 KIK44220.1 - 0.0014 18.1 0.0 1 8.7 0.0 2.6 2 1 0 2 2 2 1 Bacterial TniB protein AAA PF00004.29 KIK44220.1 - 0.0023 18.4 0.8 4.7 7.7 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KIK44220.1 - 0.0025 17.8 0.2 0.92 9.4 0.1 2.8 2 0 0 2 2 2 1 NACHT domain DLIC PF05783.11 KIK44220.1 - 0.0029 16.5 0.1 0.37 9.6 0.0 2.3 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) RNA_helicase PF00910.22 KIK44220.1 - 0.0038 17.6 0.0 2.9 8.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 KIK44220.1 - 0.0044 16.8 0.1 1.4 8.7 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein SRPRB PF09439.10 KIK44220.1 - 0.0045 16.4 0.6 0.77 9.2 0.0 3.1 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit TsaE PF02367.17 KIK44220.1 - 0.0048 16.9 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE GTP_EFTU PF00009.27 KIK44220.1 - 0.005 16.4 0.4 2.8 7.4 0.0 3.1 4 0 0 4 4 3 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KIK44220.1 - 0.0054 16.3 0.2 2.8 7.5 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.14 KIK44220.1 - 0.0054 16.0 0.0 0.24 10.6 0.0 2.3 2 0 0 2 2 2 1 KAP family P-loop domain dNK PF01712.19 KIK44220.1 - 0.0074 16.2 2.2 1.9 8.3 0.1 3.0 3 0 0 3 3 3 1 Deoxynucleoside kinase FtsK_SpoIIIE PF01580.18 KIK44220.1 - 0.0086 15.5 0.4 6.1 6.1 0.1 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family IIGP PF05049.13 KIK44220.1 - 0.009 15.1 0.4 0.9 8.5 0.1 2.3 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_10 PF12846.7 KIK44220.1 - 0.011 14.7 0.3 1.8 7.4 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_7 PF12775.7 KIK44220.1 - 0.011 15.2 0.2 5.2 6.5 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 KIK44220.1 - 0.014 15.5 2.4 1.5 8.8 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain PduV-EutP PF10662.9 KIK44220.1 - 0.015 15.0 0.2 1.3 8.8 0.0 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 KIK44220.1 - 0.021 15.4 0.6 6.3 7.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIK44220.1 - 0.028 14.1 0.1 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KIK44220.1 - 0.033 14.4 1.8 0.9 9.8 0.4 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KIK44220.1 - 0.033 14.3 0.0 0.68 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 KIK44220.1 - 0.049 12.5 0.2 4.9 6.0 0.0 3.0 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.14 KIK44220.1 - 0.054 13.5 0.1 4.7 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KIK44220.1 - 0.067 12.9 0.0 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_8 PF12780.7 KIK44220.1 - 0.072 12.4 0.1 5.2 6.3 0.1 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 MCM PF00493.23 KIK44220.1 - 0.072 12.2 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 MCM P-loop domain Metallophos PF00149.28 KIK44220.1 - 0.15 12.5 0.0 0.88 10.0 0.0 2.1 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase ATPase_2 PF01637.18 KIK44220.1 - 0.15 11.9 0.2 4 7.3 0.0 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea SMC_N PF02463.19 KIK44220.1 - 0.2 11.0 1.4 6.2 6.2 0.2 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 KIK44220.1 - 0.25 9.9 0.2 5.6 5.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KIK44220.1 - 0.35 10.6 2.7 21 4.8 0.2 3.7 3 1 1 4 4 4 0 Conserved hypothetical ATP binding protein MutS_V PF00488.21 KIK44221.1 - 7.7e-83 277.2 0.0 1.3e-82 276.4 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KIK44221.1 - 6.7e-34 117.8 0.9 6.7e-34 117.8 0.9 2.0 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 KIK44221.1 - 1.9e-15 57.3 0.4 1.2e-14 54.7 0.1 2.5 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.18 KIK44221.1 - 2.2e-15 56.7 0.7 6.3e-15 55.3 0.7 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 KIK44221.1 - 1.6e-07 31.5 0.0 4.7e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 MutS domain I ubiquitin PF00240.23 KIK44225.1 - 4.5e-137 446.0 18.7 1.3e-33 114.6 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 KIK44225.1 - 2.8e-63 209.7 20.7 3e-15 55.8 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KIK44225.1 - 3.5e-23 81.8 9.2 0.00045 20.6 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 KIK44225.1 - 4e-16 58.7 3.0 0.033 14.1 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIK44225.1 - 1.6e-14 54.0 2.7 0.11 12.6 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KIK44225.1 - 2.2e-14 53.6 8.0 0.044 14.1 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain DUF2407 PF10302.9 KIK44225.1 - 5e-13 49.5 1.1 0.36 11.4 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KIK44225.1 - 6.7e-10 39.0 0.4 1.1 9.1 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 KIK44225.1 - 4.3e-07 29.9 24.6 16 5.7 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 KIK44225.1 - 5.2e-07 29.2 0.6 1 8.7 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 KIK44225.1 - 3.9e-06 26.9 2.8 12 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Big_7 PF17957.1 KIK44225.1 - 4.4e-06 27.4 0.1 30 5.5 0.0 4.2 4 0 0 4 4 4 0 Bacterial Ig domain DUF2870 PF11069.8 KIK44225.1 - 5.8e-06 26.6 0.0 30 5.1 0.0 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 KIK44225.1 - 1e-05 25.3 3.8 11 5.9 0.0 4.3 4 0 0 4 4 4 0 ACT domain TmoB PF06234.12 KIK44225.1 - 1.1e-05 25.4 0.1 29 4.9 0.0 4.8 4 0 0 4 4 4 0 Toluene-4-monooxygenase system protein B (TmoB) UDP-g_GGTase PF06427.11 KIK44225.1 - 5.6e-05 23.2 3.2 6.9 6.8 0.0 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase ACT_4 PF13291.6 KIK44225.1 - 0.00036 21.1 0.9 73 4.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain DUF969 PF06149.12 KIK44225.1 - 0.00036 20.0 0.1 21 4.4 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) DUF493 PF04359.14 KIK44225.1 - 0.003 18.1 0.1 1.4e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 KIK44225.1 - 0.0069 16.5 0.0 91 3.3 0.0 4.2 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 KIK44225.1 - 0.011 15.9 5.3 64 3.8 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 KIK44225.1 - 0.041 13.7 9.2 43 4.1 0.1 4.4 4 0 0 4 4 4 0 FlgD Ig-like domain Tash_PEST PF07708.11 KIK44225.1 - 0.14 12.3 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif Phage_sheath_1N PF17481.2 KIK44225.1 - 0.35 11.4 8.8 51 4.4 1.5 4.0 1 1 2 3 3 3 0 Phage tail sheath protein beta-sandwich domain YcgR_2 PF12945.7 KIK44225.1 - 1.1 9.5 4.6 2.4e+02 2.0 0.0 4.0 4 0 0 4 4 4 0 Flagellar protein YcgR PI3K_p85B PF02192.16 KIK44225.1 - 1.2 9.0 8.5 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Cnl2_NKP2 PF09447.10 KIK44225.1 - 1.2 9.3 9.9 1e+02 3.2 0.1 4.4 4 0 0 4 4 4 0 Cnl2/NKP2 family protein Sec5 PF15469.6 KIK44226.1 - 1e-51 175.4 0.0 3.2e-51 173.9 0.0 1.9 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.11 KIK44226.1 - 0.0091 16.1 0.0 0.035 14.2 0.0 2.0 2 0 0 2 2 2 1 Vps51/Vps67 HMG-CoA_red PF00368.18 KIK44231.1 - 4.4e-142 473.4 4.6 6.2e-142 472.9 4.6 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 KIK44231.1 - 1.6e-14 54.0 0.1 4.7e-14 52.5 0.1 1.8 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KIK44231.1 - 3.5e-06 25.4 0.1 5.3e-06 24.8 0.1 1.2 1 0 0 1 1 1 1 Patched family HPIH PF13323.6 KIK44231.1 - 0.094 12.6 0.4 0.29 11.0 0.4 1.8 1 0 0 1 1 1 0 N-terminal domain with HPIH motif zf-C2H2 PF00096.26 KIK44232.1 - 0.00035 20.9 16.9 0.016 15.6 0.2 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KIK44232.1 - 0.001 18.8 13.5 0.011 15.4 6.6 3.2 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KIK44232.1 - 0.051 14.4 15.7 0.17 12.8 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Tubulin PF00091.25 KIK44233.1 - 1.8e-65 220.8 0.0 2.4e-65 220.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KIK44233.1 - 3.9e-48 162.8 0.0 6.1e-48 162.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KIK44233.1 - 0.00028 20.6 0.0 0.00052 19.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 KIK44234.1 - 2.7e-66 223.6 0.0 3.6e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KIK44234.1 - 5e-47 159.2 0.0 7.6e-47 158.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KIK44234.1 - 0.0012 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain WD40 PF00400.32 KIK44235.1 - 2.6e-16 59.7 3.3 0.0003 21.5 0.4 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KIK44235.1 - 0.0039 16.2 0.7 0.0098 14.9 0.2 1.7 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Plk4_PB1 PF18190.1 KIK44235.1 - 0.16 12.2 0.0 3 8.0 0.0 2.6 3 0 0 3 3 3 0 Polo-like Kinase 4 Polo Box 1 HAD_2 PF13419.6 KIK44236.1 - 2.7e-22 79.7 0.0 3.8e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK44236.1 - 1.1e-12 48.7 0.3 2.8e-06 27.8 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIK44236.1 - 2e-06 27.7 0.0 4.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KIK44236.1 - 0.0094 16.4 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sec15 PF04091.12 KIK44237.1 - 4.7e-95 318.6 0.0 1.3e-94 317.1 0.0 1.8 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Vps51 PF08700.11 KIK44237.1 - 4.4e-07 29.9 7.1 8e-07 29.1 0.8 3.7 3 0 0 3 3 3 1 Vps51/Vps67 COG5 PF10392.9 KIK44237.1 - 2.5e-06 27.7 3.4 2.5e-06 27.7 3.4 3.1 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 KIK44237.1 - 5.1e-05 23.2 9.5 6.6e-05 22.8 1.3 3.7 3 1 0 3 3 3 1 Sec8 exocyst complex component specific domain COG2 PF06148.11 KIK44237.1 - 0.00012 22.2 7.8 0.00016 21.8 2.2 3.3 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Prominin PF05478.11 KIK44237.1 - 0.0039 15.2 5.7 0.053 11.5 0.1 2.3 2 0 0 2 2 2 2 Prominin GvpK PF05121.12 KIK44237.1 - 0.008 16.2 0.0 0.33 11.0 0.0 3.3 3 0 0 3 3 2 1 Gas vesicle protein K HBB PF06777.11 KIK44237.1 - 0.0095 15.6 0.1 1.3 8.7 0.0 3.9 2 1 0 2 2 2 1 Helical and beta-bridge domain Sec5 PF15469.6 KIK44237.1 - 0.015 15.2 0.6 0.015 15.2 0.6 2.4 2 0 0 2 2 2 0 Exocyst complex component Sec5 Dor1 PF04124.12 KIK44237.1 - 0.045 12.4 7.6 0.023 13.4 3.6 2.2 2 0 0 2 2 2 0 Dor1-like family DUF2017 PF09438.10 KIK44237.1 - 0.082 12.8 0.2 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2017) GHMP_kinases_N PF00288.26 KIK44237.1 - 0.14 12.4 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 GHMP kinases N terminal domain Tropomyosin_1 PF12718.7 KIK44237.1 - 0.22 11.7 3.0 0.59 10.3 1.6 2.2 2 0 0 2 2 2 0 Tropomyosin like FliJ PF02050.16 KIK44237.1 - 3 8.1 7.7 0.62 10.3 2.0 2.9 3 0 0 3 3 2 0 Flagellar FliJ protein NPV_P10 PF05531.12 KIK44237.1 - 6.1 7.4 6.7 2.5 8.6 0.2 3.6 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Arf PF00025.21 KIK44238.1 - 6.3e-79 263.5 0.1 7.2e-79 263.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KIK44238.1 - 1.5e-14 54.2 0.0 2.1e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KIK44238.1 - 2.4e-14 53.2 0.0 2.9e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KIK44238.1 - 2.8e-13 49.8 0.0 3.1e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KIK44238.1 - 6.5e-13 48.6 1.2 3.9e-09 36.1 0.4 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KIK44238.1 - 8e-11 41.7 0.0 9.6e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIK44238.1 - 2.4e-06 27.6 0.0 3.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KIK44238.1 - 0.0066 15.8 0.7 0.019 14.3 0.7 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.6 KIK44238.1 - 0.18 11.9 0.4 0.57 10.3 0.4 2.0 1 1 0 1 1 1 0 AAA domain Arf PF00025.21 KIK44239.1 - 4e-23 81.8 0.1 4.8e-23 81.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KIK44239.1 - 1.2e-05 24.8 0.1 1.3e-05 24.7 0.1 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DSPc PF00782.20 KIK44240.1 - 5.1e-30 104.0 0.0 6e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIK44240.1 - 0.001 18.7 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KIK44240.1 - 0.0045 17.3 0.0 0.0082 16.4 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain CDKN3 PF05706.12 KIK44240.1 - 0.021 14.5 0.1 0.038 13.7 0.1 1.4 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF3245 PF11595.8 KIK44243.1 - 4.5e-07 30.4 9.3 1.6e-05 25.4 8.9 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3245) SIP1 PF04938.12 KIK44244.1 - 1.1e-23 84.2 0.0 1.6e-23 83.6 0.0 1.3 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) GPI-anchored PF10342.9 KIK44245.1 - 7.6e-07 29.8 1.2 1.1e-06 29.3 0.0 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3446 PF11928.8 KIK44245.1 - 1.3 9.4 9.1 1.7 9.0 8.4 1.7 1 1 0 1 1 1 0 Early growth response N-terminal domain QRPTase_C PF01729.19 KIK44246.1 - 2.7e-48 164.0 0.1 3.3e-48 163.6 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KIK44246.1 - 4.8e-19 68.2 0.1 1.6e-18 66.6 0.1 1.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Amidohydro_2 PF04909.14 KIK44247.1 - 4.4e-24 85.8 0.0 2.2e-23 83.5 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KIK44247.1 - 0.066 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 TatD related DNase MbeB_N PF04837.12 KIK44248.1 - 0.15 12.4 0.1 0.28 11.5 0.1 1.5 1 0 0 1 1 1 0 MbeB-like, N-term conserved region Plasmodium_Vir PF05795.11 KIK44250.1 - 1.1 8.6 3.5 1.7 8.0 3.5 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Apt1 PF10351.9 KIK44250.1 - 1.6 7.5 6.4 2.1 7.1 6.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 KIK44250.1 - 1.7 7.7 23.5 2.2 7.4 23.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 KIK44250.1 - 3.6 7.4 10.7 5.2 6.9 10.7 1.3 1 0 0 1 1 1 0 SPX domain CytochromB561_N PF09786.9 KIK44250.1 - 9.7 5.1 21.1 14 4.5 21.1 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal ECH_1 PF00378.20 KIK44251.1 - 5.7e-59 199.4 0.0 6.6e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIK44251.1 - 8.3e-31 107.7 0.2 5.5e-28 98.4 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase CLP_protease PF00574.23 KIK44251.1 - 0.19 11.6 0.0 27 4.6 0.0 2.4 1 1 1 2 2 2 0 Clp protease adh_short PF00106.25 KIK44254.1 - 5.2e-39 133.7 0.0 7.2e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK44254.1 - 9.8e-24 84.2 0.0 1.3e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KIK44254.1 - 1.7e-05 24.8 0.0 2.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sec10 PF07393.11 KIK44255.1 - 1.8e-222 740.7 2.3 2.6e-222 740.2 2.3 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF1664 PF07889.12 KIK44255.1 - 0.019 15.0 1.3 0.084 12.9 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) I_LWEQ PF01608.17 KIK44255.1 - 0.074 13.3 0.1 0.21 11.8 0.1 1.7 1 0 0 1 1 1 0 I/LWEQ domain Filament PF00038.21 KIK44255.1 - 0.091 12.3 1.8 0.22 11.1 1.8 1.6 1 0 0 1 1 1 0 Intermediate filament protein RIX1 PF08167.12 KIK44256.1 - 1.4e-33 116.2 5.4 1.4e-33 116.2 5.4 2.9 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis RNA_pol_I_TF PF04090.12 KIK44257.1 - 3.3e-11 43.0 0.9 2.4e-08 33.7 0.2 2.1 1 1 1 2 2 2 2 RNA polymerase I specific initiation factor BTAD PF03704.17 KIK44257.1 - 0.06 13.8 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial transcriptional activator domain TPR_19 PF14559.6 KIK44257.1 - 0.4 11.2 2.3 0.67 10.5 0.2 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5102 PF17104.5 KIK44258.1 - 1.7e-60 205.5 10.6 4.5e-60 204.2 10.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF5102) FEZ PF07763.13 KIK44258.1 - 0.0058 16.4 0.0 0.092 12.5 0.0 2.0 2 0 0 2 2 2 1 FEZ-like protein DUF4113 PF13438.6 KIK44260.1 - 0.05 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) Acetyltransf_14 PF03421.16 KIK44260.1 - 0.075 13.1 0.2 0.14 12.3 0.2 1.3 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase UbiA PF01040.18 KIK44265.1 - 1.2e-44 152.5 21.7 1.6e-44 152.1 21.1 1.5 1 1 1 2 2 2 1 UbiA prenyltransferase family Ost4 PF10215.9 KIK44265.1 - 0.094 12.6 0.2 0.31 10.9 0.2 1.9 1 0 0 1 1 1 0 Oligosaccaryltransferase DnaJ PF00226.31 KIK44266.1 - 1.7e-11 44.1 0.2 3e-11 43.3 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain CD225 PF04505.12 KIK44266.1 - 0.1 12.7 0.6 0.19 11.9 0.1 1.7 2 0 0 2 2 2 0 Interferon-induced transmembrane protein Ureide_permease PF07168.11 KIK44266.1 - 0.17 10.6 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Ureide permease Methyltransf_2 PF00891.18 KIK44267.1 - 1.7e-11 43.8 0.0 6.6e-09 35.4 0.0 2.0 2 0 0 2 2 2 2 O-methyltransferase domain MarR_2 PF12802.7 KIK44268.1 - 0.044 13.7 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 MarR family DAO PF01266.24 KIK44269.1 - 1.7e-42 146.3 0.0 2e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIK44269.1 - 0.00014 21.9 0.4 0.015 15.2 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KIK44269.1 - 0.0041 16.4 0.1 0.26 10.5 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK44269.1 - 0.014 15.6 0.2 0.033 14.4 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK44269.1 - 0.016 14.4 0.0 0.093 11.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KIK44269.1 - 0.19 11.4 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Methyltransf_23 PF13489.6 KIK44270.1 - 1e-14 54.7 0.0 1.4e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK44270.1 - 1.9e-12 47.7 0.0 4.7e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK44270.1 - 4.8e-12 46.4 0.0 1.2e-11 45.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK44270.1 - 6.5e-09 36.3 0.0 1.4e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK44270.1 - 2.2e-07 30.8 0.0 3.5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK44270.1 - 0.0037 16.8 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 KIK44270.1 - 0.022 14.3 0.0 4.7 6.6 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain NNMT_PNMT_TEMT PF01234.17 KIK44270.1 - 0.03 13.5 0.0 0.98 8.6 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family DIM PF08194.12 KIK44270.1 - 0.21 11.8 0.6 0.44 10.8 0.0 1.8 2 0 0 2 2 2 0 DIM protein RhoGEF PF00621.20 KIK44271.1 - 7.2e-63 212.1 3.1 1.3e-32 113.5 0.1 2.2 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.22 KIK44271.1 - 2.7e-62 210.9 0.0 4.1e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 KIK44271.1 - 1.5e-14 54.3 0.0 4.3e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 KIK44271.1 - 1.7e-05 24.8 0.0 3.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 KIK44271.1 - 0.15 12.6 0.0 0.46 11.0 0.0 1.9 1 1 0 1 1 1 0 PH domain PH_16 PF17838.1 KIK44271.1 - 0.19 11.6 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 PH domain F-box-like PF12937.7 KIK44272.1 - 5.5e-10 39.0 4.7 9.3e-10 38.2 4.7 1.4 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KIK44272.1 - 0.092 12.7 0.3 0.15 12.0 0.3 1.6 1 1 0 1 1 1 0 F-box-like domain DUF1604 PF07713.13 KIK44273.1 - 2.9e-38 129.6 0.9 2.9e-38 129.6 0.9 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KIK44273.1 - 7.6e-06 25.7 0.4 3.1e-05 23.8 0.2 2.2 2 0 0 2 2 2 1 G-patch domain WD40 PF00400.32 KIK44274.1 - 3.3e-24 84.7 0.7 2.3e-06 28.2 0.1 6.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK44274.1 - 5.8e-06 26.5 1.2 0.72 10.2 0.1 4.7 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK44274.1 - 0.0059 15.3 0.0 0.12 11.0 0.0 2.4 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Frtz PF11768.8 KIK44274.1 - 0.018 13.4 0.0 0.9 7.8 0.0 2.8 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 KIK44274.1 - 0.019 13.8 0.0 17 4.0 0.0 3.4 2 1 0 3 3 3 0 Nup133 N terminal like WD40_like PF17005.5 KIK44274.1 - 0.04 13.3 0.0 3.3 6.9 0.0 2.6 2 1 1 3 3 3 0 WD40-like domain DUF2353 PF09789.9 KIK44275.1 - 0.00046 19.6 25.8 0.024 14.0 19.8 2.6 1 1 2 3 3 3 3 Uncharacterized coiled-coil protein (DUF2353) Wtap PF17098.5 KIK44275.1 - 0.002 18.1 24.0 0.094 12.6 3.4 3.3 3 0 0 3 3 3 2 WTAP/Mum2p family HMMR_N PF15905.5 KIK44275.1 - 0.0071 15.9 30.3 0.0068 15.9 23.4 2.6 1 1 1 2 2 2 2 Hyaluronan mediated motility receptor N-terminal NRBF2 PF08961.10 KIK44275.1 - 0.0079 15.8 1.3 0.0079 15.8 1.3 3.4 1 1 2 3 3 3 1 Nuclear receptor-binding factor 2, autophagy regulator YabA PF06156.13 KIK44275.1 - 0.015 15.9 25.4 0.32 11.6 5.4 3.8 1 1 3 4 4 4 0 Initiation control protein YabA CASP_C PF08172.12 KIK44275.1 - 0.058 12.7 19.6 0.053 12.9 2.5 3.6 2 1 0 3 3 3 0 CASP C terminal MSA-2c PF12238.8 KIK44275.1 - 0.15 12.1 5.7 0.073 13.1 3.3 1.7 2 0 0 2 2 2 0 Merozoite surface antigen 2c DHR10 PF18595.1 KIK44275.1 - 0.21 11.7 30.6 0.12 12.4 12.8 3.5 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain Fez1 PF06818.15 KIK44275.1 - 0.25 11.8 29.4 0.39 11.1 23.6 2.4 1 1 1 2 2 2 0 Fez1 GAS PF13851.6 KIK44275.1 - 0.42 9.9 31.9 0.17 11.3 20.2 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 KIK44275.1 - 0.42 10.4 33.8 0.039 13.8 6.1 3.2 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 KIK44275.1 - 0.43 10.6 29.8 2.8 7.9 2.2 3.3 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HOOK PF05622.12 KIK44275.1 - 0.61 8.2 31.7 14 3.7 23.6 2.0 1 1 0 1 1 1 0 HOOK protein PI3K_P85_iSH2 PF16454.5 KIK44275.1 - 0.73 9.4 24.2 0.15 11.6 3.8 3.2 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ADIP PF11559.8 KIK44275.1 - 0.8 9.8 38.5 0.46 10.6 6.6 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 KIK44275.1 - 0.81 9.7 35.5 1.9 8.6 20.4 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein PRKG1_interact PF15898.5 KIK44275.1 - 0.91 10.5 29.8 0.33 11.9 5.0 3.3 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain CortBP2 PF09727.9 KIK44275.1 - 1 9.2 25.0 2.9 7.8 17.1 2.8 1 1 1 2 2 2 0 Cortactin-binding protein-2 WEMBL PF05701.11 KIK44275.1 - 1.2 7.8 26.6 0.54 8.9 3.2 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light V_ATPase_I PF01496.19 KIK44275.1 - 1.7 6.5 23.4 0.25 9.2 13.9 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family ERM PF00769.19 KIK44275.1 - 1.8 8.3 30.5 4.8 6.9 16.2 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ArAE_2_N PF10337.9 KIK44275.1 - 2.3 7.2 5.3 3.2 6.7 5.3 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal CALCOCO1 PF07888.11 KIK44275.1 - 3.3 6.4 30.8 0.56 9.0 2.6 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like ATG16 PF08614.11 KIK44275.1 - 4.6 7.4 39.6 17 5.6 14.5 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 KIK44275.1 - 4.7 7.5 26.4 13 6.1 2.3 3.3 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding TSC22 PF01166.18 KIK44275.1 - 5.1 7.5 22.3 5.8 7.3 1.8 5.4 4 2 2 6 6 5 0 TSC-22/dip/bun family FAM76 PF16046.5 KIK44275.1 - 5.5 6.2 22.9 4 6.7 21.2 1.6 1 1 0 1 1 1 0 FAM76 protein Cob_adeno_trans PF01923.18 KIK44275.1 - 5.9 7.0 11.0 12 6.1 0.8 2.5 1 1 1 2 2 2 0 Cobalamin adenosyltransferase MCC-bdg_PDZ PF10506.9 KIK44275.1 - 7.3 6.7 14.0 0.58 10.2 3.4 3.4 2 2 1 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome APG6_N PF17675.1 KIK44275.1 - 7.4 7.1 34.0 54 4.3 15.3 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region EMP24_GP25L PF01105.24 KIK44275.1 - 7.7 6.4 18.7 1.1 9.2 1.8 2.8 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4618 PF15397.6 KIK44275.1 - 8.5 5.7 24.2 9 5.6 15.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) Plk4_PB2 PF18409.1 KIK44275.1 - 8.5 7.1 11.0 17 6.2 4.2 2.5 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Uso1_p115_C PF04871.13 KIK44275.1 - 9 6.7 32.6 4 7.8 17.2 3.2 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region MAD PF05557.13 KIK44275.1 - 9.5 4.4 30.6 3 6.1 26.4 1.9 1 1 1 2 2 2 0 Mitotic checkpoint protein PAP2_C PF14360.6 KIK44276.1 - 0.12 12.9 0.3 1 9.9 0.3 2.3 1 1 0 1 1 1 0 PAP2 superfamily C-terminal CxC5 PF18718.1 KIK44277.1 - 3.7e-37 127.0 9.8 6.4e-37 126.2 9.8 1.4 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases IBR PF01485.21 KIK44277.1 - 0.91 9.8 5.8 1.5 9.1 3.7 2.2 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain DUF5581 PF17744.1 KIK44278.1 - 0.093 12.1 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5581) IF-2 PF11987.8 KIK44278.1 - 0.12 12.5 0.0 0.37 10.9 0.0 1.8 1 1 1 2 2 2 0 Translation-initiation factor 2 Retinin_C PF04527.12 KIK44280.1 - 0.17 12.2 6.6 2.8 8.3 0.4 2.4 1 1 1 2 2 2 0 Drosophila Retinin like protein Pinin_SDK_N PF04697.13 KIK44280.1 - 0.46 11.1 4.4 1.2 9.7 3.4 2.1 1 1 1 2 2 2 0 pinin/SDK conserved region F-box-like PF12937.7 KIK44281.1 - 4.9e-10 39.1 0.4 4.9e-10 39.1 0.4 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK44281.1 - 0.00015 21.5 4.4 0.0011 18.8 0.2 3.3 3 0 0 3 3 3 1 F-box domain Prenyltransf PF01255.19 KIK44282.1 - 7.2e-43 146.7 0.0 8.4e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Phosphodiest PF01663.22 KIK44283.1 - 1.1e-69 235.8 1.0 1.6e-69 235.2 1.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Ysc84 PF04366.12 KIK44284.1 - 3.6e-46 156.1 0.0 6e-46 155.3 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Sec7 PF01369.20 KIK44284.1 - 0.039 13.6 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 Sec7 domain Glyco_hydro_15 PF00723.21 KIK44285.1 - 1.5e-92 310.7 0.0 1.8e-92 310.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KIK44285.1 - 1.1e-26 92.5 0.9 2.2e-26 91.6 0.9 1.5 1 0 0 1 1 1 1 Starch binding domain DUF4419 PF14388.6 KIK44286.1 - 9.2e-104 347.1 0.0 1.2e-103 346.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DUF863 PF05904.11 KIK44286.1 - 0.34 9.3 3.4 0.47 8.8 3.4 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) HET PF06985.11 KIK44287.1 - 2.3e-09 37.8 3.5 2e-08 34.7 0.1 2.5 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Peptidase_S68 PF10461.9 KIK44287.1 - 0.11 12.7 0.8 0.3 11.3 0.8 1.8 1 0 0 1 1 1 0 Peptidase S68 YHS PF04945.13 KIK44289.1 - 0.0065 16.6 0.8 0.14 12.3 0.2 2.5 2 0 0 2 2 2 1 YHS domain Ecl1 PF12855.7 KIK44289.1 - 0.12 13.6 8.3 0.2 12.8 8.1 1.6 1 1 0 1 1 1 0 ECL1/2/3 zinc binding proteins zf-RING_2 PF13639.6 KIK44291.1 - 6.2e-11 42.5 3.0 6.2e-11 42.5 3.0 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KIK44291.1 - 3.7e-10 39.4 2.6 9.1e-10 38.1 2.6 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KIK44291.1 - 4e-05 23.4 2.2 8.9e-05 22.3 2.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK44291.1 - 4.9e-05 23.2 1.2 8.8e-05 22.4 1.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain PA PF02225.22 KIK44291.1 - 5e-05 23.2 0.0 8.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-C3HC4 PF00097.25 KIK44291.1 - 0.00019 21.2 1.8 0.00019 21.2 1.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK44291.1 - 0.0012 18.8 1.2 0.015 15.3 0.2 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KIK44291.1 - 0.003 17.8 7.8 0.02 15.2 7.3 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KIK44291.1 - 0.0065 16.3 1.1 0.014 15.2 1.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KIK44291.1 - 0.082 13.0 2.0 0.29 11.2 1.9 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KIK44291.1 - 0.36 10.5 4.4 0.73 9.5 4.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-CCCH PF00642.24 KIK44292.1 - 6.1e-16 57.9 32.4 3.7e-06 26.7 3.0 4.3 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIK44292.1 - 1e-13 50.8 36.8 0.00025 21.0 3.8 4.5 4 0 0 4 4 4 4 Zinc finger domain Torus PF16131.5 KIK44292.1 - 2.9e-10 40.8 17.4 0.015 15.9 0.2 4.3 3 1 0 4 4 4 4 Torus domain zf-CCCH_4 PF18044.1 KIK44292.1 - 3.4e-09 36.3 35.2 0.00018 21.2 2.7 4.4 4 0 0 4 4 4 3 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KIK44292.1 - 0.013 16.0 31.7 0.12 12.9 4.1 4.4 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KIK44292.1 - 0.85 9.9 11.4 4.2 7.6 1.2 3.8 3 1 0 3 3 3 0 Zinc-finger containing family Heme_oxygenase PF01126.20 KIK44293.1 - 1.7e-31 109.6 0.0 2.5e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Heme oxygenase Asp PF00026.23 KIK44294.1 - 1.6e-19 70.5 8.0 1.9e-16 60.4 8.0 2.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TMEM52 PF14979.6 KIK44294.1 - 0.0052 16.7 3.0 0.01 15.8 0.3 2.2 2 0 0 2 2 2 1 Transmembrane 52 TAXi_N PF14543.6 KIK44294.1 - 0.0056 16.9 3.2 2 8.6 0.4 2.7 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Tweety PF04906.13 KIK44294.1 - 0.014 14.1 0.3 0.023 13.4 0.3 1.2 1 0 0 1 1 1 0 Tweety Orthoreo_P10 PF07204.11 KIK44294.1 - 0.025 14.5 0.1 0.058 13.4 0.1 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Shisa PF13908.6 KIK44294.1 - 0.065 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator gag-asp_proteas PF13975.6 KIK44294.1 - 0.09 13.3 0.3 0.9 10.1 0.1 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TMEM132D_C PF15706.5 KIK44294.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Asp_protease_2 PF13650.6 KIK44294.1 - 0.37 11.5 3.3 0.27 11.9 0.5 2.4 3 0 0 3 3 3 0 Aspartyl protease Asp PF00026.23 KIK44295.1 - 4.5e-17 62.5 0.8 6.7e-11 42.2 0.1 2.7 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KIK44295.1 - 2.5e-06 28.0 0.9 3e-05 24.6 0.1 2.8 3 0 0 3 3 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK44295.1 - 5.6e-05 23.6 0.2 0.0015 19.0 0.0 2.9 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease RCR PF12273.8 KIK44295.1 - 0.00084 20.0 0.4 0.0019 18.8 0.4 1.6 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red CYYR1 PF10873.8 KIK44295.1 - 0.0035 17.8 0.2 0.0083 16.6 0.2 1.6 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 CD34_antigen PF06365.12 KIK44295.1 - 0.013 15.1 0.1 0.03 13.9 0.1 1.5 2 0 0 2 2 2 0 CD34/Podocalyxin family Amnionless PF14828.6 KIK44295.1 - 0.02 13.7 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Amnionless Adeno_E3_CR2 PF02439.15 KIK44295.1 - 0.026 14.3 5.0 0.061 13.1 5.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TAXi_N PF14543.6 KIK44295.1 - 0.042 14.1 6.3 0.11 12.7 0.2 3.0 3 1 1 4 4 3 0 Xylanase inhibitor N-terminal TMEM52 PF14979.6 KIK44295.1 - 0.048 13.6 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Transmembrane 52 LSR PF05624.14 KIK44295.1 - 0.12 12.4 1.9 0.22 11.6 1.9 1.3 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Stevor PF17410.2 KIK44295.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF5305 PF17231.2 KIK44295.1 - 0.19 11.1 0.0 0.43 9.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Phage_holin_2_3 PF16080.5 KIK44295.1 - 0.58 10.0 5.4 0.16 11.7 0.8 2.3 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Spore_YhaL PF14147.6 KIK44295.1 - 0.97 9.2 4.9 1.8 8.3 4.9 1.4 1 0 0 1 1 1 0 Sporulation protein YhaL DUF3439 PF11921.8 KIK44295.1 - 7.5 6.5 7.9 5.9 6.9 4.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dynactin_p62 PF05502.13 KIK44297.1 - 5.6e-71 239.8 11.0 1.4e-40 139.5 10.3 2.3 2 0 0 2 2 2 2 Dynactin p62 family TIG PF01833.24 KIK44299.1 - 0.019 15.1 0.2 0.038 14.1 0.2 1.5 1 0 0 1 1 1 0 IPT/TIG domain PLDc_2 PF13091.6 KIK44300.1 - 1.9e-13 50.5 0.0 2.5e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KIK44300.1 - 0.052 13.8 6.8 0.43 10.8 0.2 2.8 3 0 0 3 3 3 0 Phospholipase D Active site motif FAM83 PF07894.12 KIK44300.1 - 0.066 12.8 0.1 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 FAM83 A-H Q_salvage PF10343.9 KIK44302.1 - 2.4e-90 303.0 0.0 3.1e-90 302.6 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family SET PF00856.28 KIK44305.1 - 2.4e-22 80.1 0.2 1.6e-21 77.4 0.2 2.2 1 1 0 1 1 1 1 SET domain N-SET PF11764.8 KIK44305.1 - 7.5e-09 35.9 6.7 6.9e-07 29.5 6.7 2.3 1 1 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component N WD40 PF00400.32 KIK44306.1 - 7.3e-08 33.0 0.1 0.0076 17.1 0.0 3.2 2 1 1 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK44306.1 - 0.0079 16.5 0.0 2.4 8.5 0.0 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KIK44306.1 - 0.011 15.4 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 0 PQQ-like domain Cytochrom_D1 PF02239.16 KIK44306.1 - 0.035 12.6 0.0 0.042 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytochrome D1 heme domain SNF5 PF04855.12 KIK44307.1 - 6e-76 255.4 1.3 1.2e-75 254.3 0.1 2.0 2 1 0 2 2 2 1 SNF5 / SMARCB1 / INI1 zf-C2H2 PF00096.26 KIK44313.1 - 5.7e-09 35.9 9.7 0.00013 22.2 1.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK44313.1 - 3.7e-08 33.4 13.1 7.6e-06 26.1 2.7 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK44313.1 - 3.7e-05 24.2 8.0 0.076 13.9 1.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KIK44313.1 - 0.022 15.0 0.4 0.061 13.6 0.4 1.7 1 0 0 1 1 1 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 KIK44313.1 - 0.12 13.0 0.8 1.9 9.2 0.1 2.4 1 1 1 2 2 2 0 FOXP coiled-coil domain WD40 PF00400.32 KIK44314.1 - 4.1e-11 43.2 11.5 0.0036 18.1 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Gelsolin PF00626.22 KIK44315.1 - 1.3e-19 69.8 0.6 1.9e-11 43.7 0.0 2.7 3 0 0 3 3 3 2 Gelsolin repeat Methyltransf_33 PF10017.9 KIK44316.1 - 4.1e-73 246.2 0.0 2e-72 243.9 0.0 1.9 1 1 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KIK44316.1 - 3.5e-21 75.9 0.5 3.9e-12 46.3 0.0 2.2 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KIK44316.1 - 1.6e-05 25.4 0.2 3.8e-05 24.2 0.2 1.6 1 0 0 1 1 1 1 DinB superfamily DHHC PF01529.20 KIK44318.1 - 2e-33 115.3 5.2 2e-33 115.3 5.2 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase CSN8_PSD8_EIF3K PF10075.9 KIK44319.1 - 0.028 14.4 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family F-box-like PF12937.7 KIK44320.1 - 1.6e-06 27.9 0.9 2.9e-06 27.1 0.9 1.5 1 0 0 1 1 1 1 F-box-like p450 PF00067.22 KIK44321.1 - 1.5e-63 215.2 0.0 4.6e-63 213.6 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 PAP2_3 PF14378.6 KIK44323.1 - 0.0028 17.4 6.6 0.057 13.1 6.6 2.1 1 1 0 1 1 1 1 PAP2 superfamily DUF3605 PF12239.8 KIK44324.1 - 2.8e-28 99.2 0.0 3.4e-18 66.4 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) Flavoprotein PF02441.19 KIK44325.1 - 4.3e-44 150.1 0.0 4.8e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein RsfS PF02410.15 KIK44326.1 - 5.9e-06 26.6 0.0 9.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation p450 PF00067.22 KIK44327.1 - 1e-61 209.2 0.0 2e-61 208.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 GST_N_3 PF13417.6 KIK44328.1 - 3.4e-10 40.2 0.0 7.6e-10 39.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK44328.1 - 4.9e-07 30.0 0.1 9.3e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK44328.1 - 6.5e-06 26.1 0.1 1.3e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK44328.1 - 0.048 13.9 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIK44328.1 - 0.073 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KIK44328.1 - 0.099 13.4 0.0 0.42 11.4 0.0 2.0 2 1 1 3 3 3 0 Glutathione S-transferase N-terminal domain WD40 PF00400.32 KIK44329.1 - 2e-10 41.0 0.0 3.7e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat TPR_MLP1_2 PF07926.12 KIK44330.1 - 3.7e-24 85.2 21.8 3.7e-24 85.2 21.8 18.8 6 4 12 20 20 20 5 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.6 KIK44330.1 - 0.0062 16.6 2.5 0.0062 16.6 2.5 19.6 15 5 6 21 21 21 3 Centrosome localisation domain of PPC89 MMgT PF10270.9 KIK44330.1 - 0.25 11.7 3.0 3.4 8.1 0.2 3.9 3 1 0 3 3 3 0 Membrane magnesium transporter Mob1_phocein PF03637.17 KIK44331.1 - 1e-67 227.4 1.3 1.3e-67 227.1 1.3 1.1 1 0 0 1 1 1 1 Mob1/phocein family Plavaka PF18759.1 KIK44335.1 - 7.1e-82 275.2 0.2 9.6e-82 274.8 0.2 1.2 1 0 0 1 1 1 1 Plavaka transposase CH PF00307.31 KIK44336.1 - 5e-79 261.6 0.0 1.5e-20 73.4 0.0 4.6 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KIK44336.1 - 1.6e-06 27.9 0.0 11 6.0 0.0 4.4 4 0 0 4 4 4 4 CAMSAP CH domain CH_2 PF06294.11 KIK44336.1 - 0.13 12.4 0.0 3.5 7.8 0.0 2.7 2 0 0 2 2 2 0 CH-like domain in sperm protein Ribosomal_L16 PF00252.18 KIK44337.1 - 1.2e-36 125.6 0.4 1.4e-36 125.4 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF4140 PF13600.6 KIK44338.1 - 0.069 13.6 2.6 13 6.3 0.4 3.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF1192 PF06698.11 KIK44338.1 - 0.093 12.8 0.0 0.36 10.9 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) CoA_transf_3 PF02515.17 KIK44339.1 - 1.2e-122 409.7 0.0 1.3e-122 409.5 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Hpt PF01627.23 KIK44340.1 - 6.8e-11 42.3 0.0 8.3e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Hpt domain Helicase_C_2 PF13307.6 KIK44341.1 - 3.6e-54 183.5 0.0 8.8e-54 182.2 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KIK44341.1 - 1.3e-44 152.0 0.0 2.4e-44 151.1 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 KIK44341.1 - 0.00042 20.4 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit PhoH PF02562.16 KIK44341.1 - 0.00076 19.0 0.0 0.27 10.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_22 PF13401.6 KIK44341.1 - 0.0013 19.0 0.0 0.39 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIK44341.1 - 0.0031 17.3 0.2 0.023 14.4 0.1 2.3 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 KIK44341.1 - 0.0061 16.3 0.4 0.072 12.8 0.4 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_25 PF13481.6 KIK44341.1 - 0.046 13.3 0.0 6.8 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KIK44341.1 - 0.098 11.7 0.0 0.23 10.5 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.6 KIK44341.1 - 0.1 12.4 1.6 0.34 10.6 0.2 2.5 2 1 0 2 2 2 0 AAA domain Na_Ca_ex PF01699.24 KIK44342.1 - 3.4e-21 75.8 27.0 1.6e-13 50.9 11.7 3.4 4 0 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 KIK44342.1 - 5.8e-15 55.7 16.1 5.8e-15 55.7 16.1 4.0 3 0 0 3 3 3 1 Inner membrane component domain DUF5523 PF17661.1 KIK44342.1 - 0.096 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) SLATT_5 PF18160.1 KIK44342.1 - 0.12 11.7 0.3 0.48 9.7 0.3 2.0 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Borrelia_P13 PF05628.12 KIK44342.1 - 0.38 10.7 2.6 1 9.3 2.6 1.7 1 0 0 1 1 1 0 Borrelia membrane protein P13 NOA36 PF06524.12 KIK44342.1 - 3.5 6.9 4.8 5.9 6.1 4.8 1.2 1 0 0 1 1 1 0 NOA36 protein MMS1_N PF10433.9 KIK44343.1 - 7.2e-60 203.0 0.0 5e-59 200.2 0.0 2.1 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KIK44343.1 - 3.7e-50 171.1 0.0 1.2e-48 166.2 0.0 2.5 3 0 0 3 3 3 1 CPSF A subunit region She9_MDM33 PF05546.11 KIK44344.1 - 1.2e-71 240.6 8.8 1.8e-71 240.1 8.8 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family DUF2371 PF10177.9 KIK44344.1 - 0.45 10.7 2.5 0.58 10.3 0.2 2.2 2 2 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) FAD_binding_1 PF00667.20 KIK44345.1 - 8.1e-55 185.8 0.0 4.4e-54 183.4 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KIK44345.1 - 2.2e-31 109.0 1.7 2.6e-31 108.7 0.4 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KIK44345.1 - 8.5e-20 71.4 0.0 1.9e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KIK44345.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain Yae1_N PF09811.9 KIK44346.1 - 3.7e-09 36.1 0.6 8.6e-09 35.0 0.6 1.7 1 0 0 1 1 1 1 Essential protein Yae1, N terminal UAA PF08449.11 KIK44347.1 - 1.3e-41 142.8 13.9 7.6e-41 140.3 13.9 1.9 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KIK44347.1 - 1.8e-06 28.1 9.0 1.8e-06 28.1 9.0 4.2 4 1 0 4 4 4 2 EamA-like transporter family CRT-like PF08627.10 KIK44347.1 - 6.3e-06 25.4 6.1 0.001 18.1 0.6 2.2 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 KIK44347.1 - 0.015 14.5 5.9 0.18 10.9 0.9 2.2 2 0 0 2 2 2 0 Nucleotide-sugar transporter DSPc PF00782.20 KIK44348.1 - 1.7e-24 86.1 0.0 2.1e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KIK44348.1 - 0.025 14.9 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KIK44348.1 - 0.17 11.4 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase cobW PF02492.19 KIK44349.1 - 5e-48 163.0 0.1 7.4e-48 162.5 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KIK44349.1 - 2e-06 27.6 0.0 3.9e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 KIK44349.1 - 4.1e-05 23.2 0.0 0.0071 15.9 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIK44349.1 - 0.00015 21.8 0.0 0.00031 20.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK44349.1 - 0.00055 19.9 0.0 0.65 9.9 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KIK44349.1 - 0.0057 17.1 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK44349.1 - 0.0062 16.8 0.0 0.048 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KIK44349.1 - 0.014 14.4 0.7 0.25 10.3 0.0 2.9 4 0 0 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 KIK44349.1 - 0.017 14.8 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Arf PF00025.21 KIK44349.1 - 0.02 14.3 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_18 PF13238.6 KIK44349.1 - 0.031 14.8 0.1 0.11 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KIK44349.1 - 0.06 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIK44349.1 - 0.14 12.7 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 KIK44350.1 - 2e-59 200.4 0.0 3.9e-59 199.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KIK44350.1 - 2.8e-10 40.1 0.0 3.3e-07 30.3 0.0 2.7 2 0 0 2 2 2 2 Elongation factor G C-terminus EFG_II PF14492.6 KIK44350.1 - 2.4e-07 30.7 0.0 7.9e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KIK44350.1 - 2.4e-05 24.6 0.0 6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIK44350.1 - 9.6e-05 22.4 0.0 0.00024 21.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_IV PF03764.18 KIK44350.1 - 0.018 14.9 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor G, domain IV RasGEF PF00617.19 KIK44351.1 - 5.9e-55 186.2 0.2 1.2e-54 185.3 0.2 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KIK44351.1 - 3.1e-21 75.6 0.1 8.6e-21 74.2 0.1 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KIK44351.1 - 4.8e-16 58.1 0.1 1.2e-15 56.9 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK44351.1 - 8e-11 41.6 0.1 1.8e-10 40.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIK44351.1 - 6.8e-10 38.5 0.0 1.4e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 KIK44351.1 - 3.1e-09 36.8 2.4 0.00058 19.9 0.9 2.6 2 0 0 2 2 2 2 WW domain TaqI_C PF12950.7 KIK44351.1 - 0.15 12.1 0.0 19 5.3 0.0 2.4 2 0 0 2 2 2 0 TaqI-like C-terminal specificity domain Amidohydro_3 PF07969.11 KIK44352.1 - 0.084 12.3 1.4 0.13 11.7 0.2 2.0 2 1 0 2 2 2 0 Amidohydrolase family DLH PF01738.18 KIK44354.1 - 1.3e-15 57.5 0.0 1.7e-15 57.2 0.0 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KIK44354.1 - 0.02 14.6 0.0 0.18 11.4 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.11 KIK44354.1 - 0.097 12.6 0.0 0.75 9.7 0.0 1.9 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal GPI-anchored PF10342.9 KIK44355.1 - 0.00016 22.4 0.1 0.0002 22.0 0.1 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KIK44355.1 - 0.032 14.0 0.0 0.048 13.4 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) DPBB_1 PF03330.18 KIK44357.1 - 0.0029 17.9 0.0 0.0087 16.3 0.0 1.9 1 1 0 1 1 1 1 Lytic transglycolase SH3_9 PF14604.6 KIK44359.1 - 7.1e-26 89.8 1.3 4.5e-14 52.0 0.3 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KIK44359.1 - 8.7e-22 76.5 0.2 4.6e-10 39.0 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KIK44359.1 - 5.2e-20 70.9 0.1 1.3e-11 44.0 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 KIK44359.1 - 2.3e-13 50.2 0.2 5.6e-13 49.0 0.2 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.22 KIK44359.1 - 1.3e-11 44.2 3.9 2.5e-11 43.3 3.9 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.11 KIK44359.1 - 1.7e-05 25.0 0.3 1.7e-05 25.0 0.3 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_4 PF06347.13 KIK44359.1 - 0.016 15.0 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain CAF1 PF04857.20 KIK44361.1 - 3e-20 72.7 0.1 3.4e-11 42.9 0.0 2.6 1 1 0 2 2 2 2 CAF1 family ribonuclease Fungal_trans PF04082.18 KIK44362.1 - 5.3e-19 68.3 2.0 1.6e-18 66.7 2.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK44362.1 - 0.00019 21.5 12.6 0.00038 20.5 12.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Carn_acyltransf PF00755.20 KIK44363.1 - 4.6e-198 659.6 0.0 5.3e-198 659.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Peptidase_C97 PF05903.14 KIK44364.1 - 8.9e-40 136.0 0.0 1.4e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 KIK44364.1 - 8.9e-33 113.7 1.8 1.7e-32 112.8 1.8 1.4 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.20 KIK44364.1 - 9.2e-16 57.7 0.0 1.8e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KIK44364.1 - 4e-07 30.4 0.0 8.9e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KIK44364.1 - 0.00016 21.1 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 KIK44364.1 - 0.0018 18.0 0.0 0.0058 16.4 0.0 1.8 2 0 0 2 2 2 1 Redoxin RPA_interact_M PF14767.6 KIK44364.1 - 0.024 15.2 0.4 0.055 14.0 0.4 1.5 1 0 0 1 1 1 0 Replication protein A interacting middle DUF2847 PF11009.8 KIK44364.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) HyaE PF07449.11 KIK44364.1 - 0.091 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 KIK44364.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like F-box-like PF12937.7 KIK44365.1 - 1.2e-07 31.5 0.0 4.3e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 F-box-like Pkinase PF00069.25 KIK44366.1 - 9.2e-55 185.8 0.0 1.2e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK44366.1 - 2.5e-26 92.5 0.0 4.5e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KIK44366.1 - 0.00096 18.8 0.4 0.0055 16.3 0.1 2.2 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 KIK44366.1 - 0.0055 16.1 0.1 0.015 14.6 0.1 1.6 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KIK44366.1 - 0.0071 16.0 0.1 0.7 9.5 0.1 2.3 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIK44366.1 - 0.0073 15.7 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK44366.1 - 0.2 10.4 0.1 0.44 9.3 0.1 1.5 1 0 0 1 1 1 0 Fungal protein kinase BTB PF00651.31 KIK44367.1 - 0.0037 17.5 0.0 0.013 15.8 0.0 1.9 2 1 1 3 3 3 1 BTB/POZ domain zf-MYND PF01753.18 KIK44369.1 - 2.1e-08 34.1 14.1 4.5e-08 33.0 14.1 1.6 1 0 0 1 1 1 1 MYND finger TPR_12 PF13424.6 KIK44369.1 - 0.0023 18.2 0.2 18 5.7 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-C6H2 PF15801.5 KIK44369.1 - 0.054 13.8 13.2 0.14 12.4 13.2 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding TPR_14 PF13428.6 KIK44369.1 - 0.077 13.9 3.7 29 5.8 0.0 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat AhpC-TSA PF00578.21 KIK44370.1 - 1.7e-26 92.6 0.0 2.4e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIK44370.1 - 5.9e-14 52.0 0.0 9.3e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KIK44370.1 - 0.0012 19.0 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme PH_6 PF15406.6 KIK44370.1 - 0.041 14.2 0.1 0.058 13.7 0.1 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain zf-Tim10_DDP PF02953.15 KIK44372.1 - 1.2e-19 69.6 5.4 1.3e-19 69.5 4.9 1.3 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Phasin_2 PF09361.10 KIK44372.1 - 0.021 15.1 0.0 1.2 9.4 0.0 2.1 1 1 1 2 2 2 0 Phasin protein OHCU_decarbox PF09349.10 KIK44372.1 - 0.05 14.1 0.0 0.066 13.7 0.0 1.1 1 0 0 1 1 1 0 OHCU decarboxylase LuxT_C PF18285.1 KIK44372.1 - 0.081 13.5 0.5 0.1 13.2 0.5 1.1 1 0 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain DAHP_synth_1 PF00793.20 KIK44373.1 - 1.4e-95 319.4 0.0 1.7e-95 319.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family F-box-like PF12937.7 KIK44376.1 - 5.8e-06 26.1 4.7 2e-05 24.4 4.7 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK44376.1 - 0.55 10.2 8.9 4.1 7.4 8.9 2.5 1 1 0 1 1 1 0 F-box domain Ribosomal_S19e PF01090.19 KIK44377.1 - 3.2e-57 192.1 0.1 3.7e-57 191.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ribosomal_60s PF00428.19 KIK44377.1 - 0.015 15.9 6.8 0.022 15.3 6.8 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein MPP6 PF10175.9 KIK44377.1 - 0.26 11.8 4.5 0.34 11.4 4.5 1.1 1 0 0 1 1 1 0 M-phase phosphoprotein 6 WD40 PF00400.32 KIK44378.1 - 9.5e-09 35.8 0.3 0.0074 17.1 0.5 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat RCC1_2 PF13540.6 KIK44378.1 - 0.046 13.5 0.1 0.45 10.4 0.0 2.3 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat ANAPC4_WD40 PF12894.7 KIK44378.1 - 0.052 13.9 0.1 0.7 10.2 0.0 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK44378.1 - 0.07 12.1 0.0 0.12 11.3 0.0 1.6 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HTH_23 PF13384.6 KIK44379.1 - 0.0074 16.1 0.0 0.0087 15.8 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 KIK44379.1 - 0.013 15.5 1.3 0.058 13.4 1.1 2.1 1 1 0 1 1 1 0 Winged helix-turn helix Sigma70_r4_2 PF08281.12 KIK44379.1 - 0.033 13.9 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.6 KIK44379.1 - 0.074 12.6 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.6 KIK44379.1 - 0.09 12.2 0.8 0.12 11.8 0.8 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 GerE PF00196.19 KIK44379.1 - 0.11 12.0 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_26 PF13443.6 KIK44379.1 - 0.15 12.5 0.0 0.2 12.1 0.0 1.2 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Ribosomal_L4 PF00573.22 KIK44381.1 - 5.9e-39 133.7 1.0 1e-38 132.9 1.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KIK44381.1 - 8.8e-29 99.4 3.9 3.3e-28 97.5 1.2 2.4 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Syntaxin_2 PF14523.6 KIK44383.1 - 5.7e-23 81.2 6.9 7.3e-21 74.4 5.6 2.2 2 0 0 2 2 2 2 Syntaxin-like protein SNARE PF05739.19 KIK44383.1 - 6.9e-13 48.4 1.6 2.3e-12 46.7 0.5 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KIK44383.1 - 1.2e-06 28.4 10.3 3.8e-06 26.7 10.3 1.9 1 1 0 1 1 1 1 Syntaxin FlaC_arch PF05377.11 KIK44383.1 - 0.057 13.8 1.8 20 5.7 0.0 3.8 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) MPS2 PF17060.5 KIK44383.1 - 0.059 12.6 2.4 0.092 12.0 2.2 1.4 1 1 0 1 1 1 0 Monopolar spindle protein 2 DUF2730 PF10805.8 KIK44383.1 - 0.18 11.9 2.4 2.5 8.2 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Synaptobrevin PF00957.21 KIK44383.1 - 0.26 11.1 2.1 0.26 11.1 0.4 2.0 2 1 0 2 2 2 0 Synaptobrevin UPF0014 PF03649.13 KIK44385.1 - 7.6e-72 241.5 18.2 9.2e-72 241.3 18.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) BPD_transp_1 PF00528.22 KIK44385.1 - 9.8e-05 22.2 6.3 9.8e-05 22.2 6.3 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Tubulin_2 PF13809.6 KIK44385.1 - 0.00033 20.0 0.0 0.00047 19.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin like DUF3767 PF12597.8 KIK44385.1 - 0.19 11.6 3.9 9.7 6.1 0.7 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3767) OATP PF03137.20 KIK44385.1 - 6.7 4.9 11.0 4.2 5.5 4.8 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_transf_22 PF03901.17 KIK44386.1 - 3.6e-36 125.3 16.8 5.1e-36 124.8 16.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family ADH_zinc_N PF00107.26 KIK44389.1 - 6e-11 42.4 0.0 1.1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK44389.1 - 8.5e-08 32.1 0.1 1.4e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIK44389.1 - 0.00026 22.0 0.0 0.00047 21.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2374 PF09574.10 KIK44389.1 - 0.47 10.3 2.0 0.98 9.3 1.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (Duf2374) ADH_zinc_N PF00107.26 KIK44390.1 - 4.2e-15 55.9 0.0 7.4e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK44390.1 - 3.4e-08 33.3 0.0 6.6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIK44390.1 - 5.5e-06 27.5 0.0 9.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NmrA PF05368.13 KIK44390.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family PA28_beta PF02252.18 KIK44392.1 - 0.095 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Proteasome activator pa28 beta subunit Mito_fiss_reg PF05308.11 KIK44393.1 - 0.044 13.9 0.1 0.067 13.3 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF2890 PF11081.8 KIK44393.1 - 0.082 13.0 0.9 0.11 12.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Pro_isomerase PF00160.21 KIK44394.1 - 1.1e-45 155.8 0.0 1.2e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KIK44395.1 - 5.5e-12 45.3 0.0 9.4e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) P34-Arc PF04045.14 KIK44396.1 - 7.8e-111 369.5 0.5 9.7e-111 369.2 0.5 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Tweety PF04906.13 KIK44396.1 - 0.12 11.0 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Tweety HET PF06985.11 KIK44398.1 - 1.8e-11 44.6 3.6 1.9e-09 38.0 0.2 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) WD40 PF00400.32 KIK44399.1 - 5.3e-23 80.9 2.5 3.4e-08 34.0 0.3 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK44399.1 - 2.2e-07 31.1 0.0 0.063 13.6 0.0 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK44399.1 - 0.00024 20.2 0.0 0.16 10.9 0.0 2.9 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK44399.1 - 0.0096 14.6 0.2 0.059 12.0 0.1 1.8 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Alba PF01918.21 KIK44400.1 - 2.9e-05 23.8 0.0 0.00033 20.4 0.0 2.5 1 1 0 1 1 1 1 Alba PHD PF00628.29 KIK44401.1 - 3.5e-06 26.8 8.3 6.8e-06 25.9 8.3 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KIK44401.1 - 0.019 15.2 2.3 0.048 13.9 2.3 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF668 PF05003.12 KIK44401.1 - 0.072 13.6 0.1 0.28 11.7 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF668) DUF1748 PF08520.10 KIK44402.1 - 4.9e-25 87.2 0.1 5.5e-25 87.1 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) HET PF06985.11 KIK44404.1 - 8.7e-27 94.3 0.0 1.3e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) YqgC PF17430.2 KIK44404.1 - 0.078 13.1 0.4 0.16 12.1 0.2 1.6 2 0 0 2 2 2 0 Uncharacterized YqgC-like Citrate_synt PF00285.21 KIK44405.1 - 5.4e-99 331.7 0.0 6.4e-99 331.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Methyltransf_4 PF02390.17 KIK44406.1 - 1.5e-54 184.1 0.0 1.9e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KIK44406.1 - 9.2e-06 26.3 0.0 1.8e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK44406.1 - 0.00073 19.4 0.0 0.0011 18.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK44406.1 - 0.003 18.2 0.0 0.02 15.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK44406.1 - 0.014 16.1 0.0 0.034 14.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KIK44406.1 - 0.025 14.1 0.0 0.066 12.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain RNase_PH PF01138.21 KIK44407.1 - 4.3e-34 117.9 0.0 1.1e-33 116.6 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KIK44407.1 - 0.00056 19.9 0.0 0.00095 19.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 NAPRTase PF04095.16 KIK44408.1 - 5.4e-62 209.5 0.1 6.9e-62 209.2 0.1 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KIK44408.1 - 2.1e-34 118.6 0.1 3.9e-34 117.7 0.1 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain YARHG PF13308.6 KIK44408.1 - 0.025 14.5 0.1 0.13 12.1 0.1 2.3 2 0 0 2 2 2 0 YARHG domain Glyco_hydro_79C PF16862.5 KIK44409.1 - 2.9e-16 60.2 0.2 7.1e-16 59.0 0.2 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain zf-met PF12874.7 KIK44410.1 - 0.0012 19.1 0.2 0.0021 18.4 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIK44410.1 - 0.0022 18.2 0.0 0.0042 17.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding MPDZ_u10 PF16667.5 KIK44410.1 - 0.0066 17.3 3.0 0.017 16.0 3.0 1.7 1 0 0 1 1 1 1 Unstructured region 10 on multiple PDZ protein PIG-L PF02585.17 KIK44410.1 - 0.013 16.1 0.1 0.025 15.2 0.1 1.5 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase zf-C2H2_2 PF12756.7 KIK44410.1 - 0.014 15.7 0.2 0.026 14.9 0.2 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) OrsD PF12013.8 KIK44410.1 - 0.02 15.3 0.2 0.044 14.2 0.2 1.6 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D CTU2 PF10288.9 KIK44410.1 - 0.88 9.8 5.9 0.12 12.6 1.5 1.9 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 UbiA PF01040.18 KIK44412.1 - 5.9e-56 189.6 18.0 8.6e-56 189.0 18.0 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Collar PF07484.12 KIK44412.1 - 0.12 12.5 0.1 0.29 11.2 0.1 1.7 1 0 0 1 1 1 0 Phage Tail Collar Domain U1snRNP70_N PF12220.8 KIK44413.1 - 1.7e-26 92.7 0.2 2.5e-26 92.1 0.2 1.2 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KIK44413.1 - 1.3e-18 66.6 0.0 2e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Homeodomain PF00046.29 KIK44414.1 - 3.3e-18 65.3 2.9 5.5e-18 64.6 2.9 1.4 1 0 0 1 1 1 1 Homeodomain zf-Tim10_DDP PF02953.15 KIK44415.1 - 6.1e-25 86.6 0.4 8.9e-25 86.1 0.4 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Cytomega_TRL10 PF06084.11 KIK44415.1 - 0.013 15.5 0.6 0.018 15.1 0.6 1.2 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein PET10 PF17316.2 KIK44415.1 - 0.042 13.4 0.0 0.046 13.2 0.0 1.1 1 0 0 1 1 1 0 Petite colonies protein 10 DnaJ PF00226.31 KIK44416.1 - 4.5e-26 90.8 1.3 9.6e-25 86.5 0.3 2.7 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 KIK44416.1 - 8.2e-09 35.5 0.3 8.2e-09 35.5 0.3 2.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIK44416.1 - 4.2e-08 33.3 0.5 4.2e-08 33.3 0.5 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KIK44416.1 - 1.1e-07 32.1 1.4 0.009 16.3 0.2 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KIK44416.1 - 0.00026 21.6 1.9 0.8 10.7 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK44416.1 - 0.00044 20.5 3.4 0.35 11.4 0.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KIK44416.1 - 0.003 17.5 2.0 0.16 12.0 0.3 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger DUF2256 PF10013.9 KIK44416.1 - 0.17 12.0 3.9 7 6.9 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RanBP PF00641.18 KIK44416.1 - 1.8 7.9 4.6 9.7 5.6 0.3 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others CTU2 PF10288.9 KIK44416.1 - 6.8 7.0 7.2 14 6.0 0.2 2.7 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Prp18 PF02840.15 KIK44417.1 - 1.2e-61 207.0 0.1 1.2e-61 207.0 0.1 2.2 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 KIK44417.1 - 1e-10 40.9 7.1 1e-10 40.9 7.1 2.0 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Phage_TAC_12 PF12363.8 KIK44417.1 - 0.059 13.8 0.2 0.23 11.9 0.1 2.1 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC Atrophin-1 PF03154.15 KIK44417.1 - 1.2 7.3 13.1 2 6.6 13.1 1.3 1 0 0 1 1 1 0 Atrophin-1 family COX6B PF02297.17 KIK44418.1 - 1e-19 70.6 6.5 1.2e-19 70.3 6.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 KIK44418.1 - 0.031 14.3 1.7 0.052 13.6 1.7 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Adaptin_N PF01602.20 KIK44419.1 - 2.2e-113 379.6 2.7 3.1e-93 313.1 4.9 2.0 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 KIK44419.1 - 4.6e-18 65.8 4.3 3.5e-16 59.7 0.2 3.4 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIK44419.1 - 1.1e-08 35.3 21.0 0.00021 21.6 0.5 6.6 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.22 KIK44419.1 - 1.8e-06 27.7 15.1 0.18 12.1 0.0 8.2 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.6 KIK44419.1 - 0.001 19.5 7.9 4 8.1 0.1 6.1 5 1 1 6 6 6 1 HEAT-like repeat Cohesin_HEAT PF12765.7 KIK44419.1 - 0.37 11.2 5.3 7.9 6.9 0.2 3.6 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Ribosomal_S10 PF00338.22 KIK44420.1 - 2.4e-28 98.2 0.4 3e-28 97.9 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF572 PF04502.13 KIK44421.1 - 1.4e-67 228.7 1.0 1.7e-67 228.5 1.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) STAT_int PF02865.17 KIK44421.1 - 0.13 12.7 0.1 0.23 11.9 0.1 1.3 1 0 0 1 1 1 0 STAT protein, protein interaction domain ARID PF01388.21 KIK44422.1 - 4.1e-12 46.6 0.2 2.7e-11 44.0 0.0 2.4 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Med15_fungi PF05397.12 KIK44422.1 - 0.00038 20.7 3.3 0.00038 20.7 3.3 2.2 3 0 0 3 3 3 1 Mediator complex subunit 15 DUF1601 PF07671.11 KIK44422.1 - 0.0019 18.0 0.1 0.0082 16.0 0.1 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1601) RasGAP_C PF03836.15 KIK44422.1 - 0.014 15.6 0.5 0.062 13.4 0.1 2.1 2 0 0 2 2 2 0 RasGAP C-terminus SO_alpha_A3 PF17806.1 KIK44422.1 - 0.062 13.6 0.1 0.19 12.1 0.1 1.8 1 0 0 1 1 1 0 Sarcosine oxidase A3 domain SNARE_assoc PF09335.11 KIK44424.1 - 3.8e-11 43.5 4.4 3.8e-11 43.5 4.4 2.0 3 0 0 3 3 3 1 SNARE associated Golgi protein E1-E2_ATPase PF00122.20 KIK44424.1 - 1.3 8.5 3.0 1.4 8.4 1.3 1.9 1 1 1 2 2 2 0 E1-E2 ATPase Peptidase_U4 PF03419.13 KIK44424.1 - 9.4 5.4 6.1 1.7 7.9 0.3 2.1 1 1 1 2 2 2 0 Sporulation factor SpoIIGA Fungal_trans PF04082.18 KIK44425.1 - 3.8e-14 52.3 0.3 6.4e-14 51.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK44425.1 - 6.4e-08 32.6 13.7 1.2e-07 31.7 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4805 PF16063.5 KIK44425.1 - 0.22 10.8 4.4 0.19 11.1 1.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4805) DnaJ PF00226.31 KIK44426.1 - 2.2e-17 62.9 0.2 9.5e-17 60.9 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain cobW PF02492.19 KIK44427.1 - 4e-41 140.5 0.1 5.3e-41 140.1 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KIK44427.1 - 0.002 18.0 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.6 KIK44427.1 - 0.016 15.6 0.0 0.028 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 KIK44427.1 - 0.017 15.1 0.0 0.041 13.8 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF1574 PF07611.11 KIK44427.1 - 0.054 12.8 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) Pox_A32 PF04665.12 KIK44427.1 - 0.062 12.8 0.2 0.49 9.8 0.0 2.3 3 0 0 3 3 3 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 KIK44427.1 - 0.082 12.8 0.1 1.8 8.5 0.0 2.4 2 1 0 2 2 2 0 RsgA GTPase ALS2CR8 PF15299.6 KIK44427.1 - 0.15 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 NikR_C PF08753.11 KIK44427.1 - 0.45 10.7 4.5 1.6 8.9 0.2 2.5 2 0 0 2 2 2 0 NikR C terminal nickel binding domain Retrotran_gag_2 PF14223.6 KIK44429.1 - 2.4e-10 40.2 0.0 3.3e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Pkinase_fungal PF17667.1 KIK44433.1 - 2.9e-26 92.2 0.0 8e-14 51.2 0.4 2.1 1 1 1 2 2 2 2 Fungal protein kinase adh_short_C2 PF13561.6 KIK44434.1 - 1.7e-63 214.3 0.1 2e-63 214.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK44434.1 - 1.1e-45 155.5 0.0 1.4e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK44434.1 - 1e-05 25.5 0.2 1e-05 25.5 0.2 1.4 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 KIK44434.1 - 0.0061 16.5 0.2 0.013 15.4 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF962 PF06127.11 KIK44435.1 - 8.3e-24 83.5 2.9 4.7e-23 81.1 2.9 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Longin PF13774.6 KIK44436.1 - 5.9e-25 87.1 0.0 9.1e-25 86.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KIK44436.1 - 4.7e-15 55.1 0.1 7.5e-15 54.5 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin mCpol PF18182.1 KIK44436.1 - 0.0094 16.3 0.1 0.1 13.0 0.0 2.2 2 0 0 2 2 2 1 minimal CRISPR polymerase domain DUF4646 PF15496.6 KIK44438.1 - 5.3e-09 36.8 1.3 6.2e-05 23.6 0.5 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF4646) SR-25 PF10500.9 KIK44438.1 - 9.3e-06 25.4 5.8 9.3e-06 25.4 5.8 2.3 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein D123 PF07065.14 KIK44438.1 - 2.1 7.4 6.6 0.53 9.4 0.8 2.0 2 0 0 2 2 2 0 D123 HET PF06985.11 KIK44439.1 - 6.2e-09 36.4 2.9 9e-06 26.1 0.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF4646 PF15496.6 KIK44442.1 - 6.5e-07 30.0 7.5 0.00038 21.1 0.7 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4646) XRN_N PF03159.18 KIK44443.1 - 3.8e-64 216.4 0.0 4.6e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus SUV3_C PF12513.8 KIK44443.1 - 0.048 13.6 0.2 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal NS3 PF17530.2 KIK44443.1 - 0.082 12.5 0.1 0.16 11.5 0.1 1.5 1 1 1 2 2 2 0 Non-structural protein NS3 IF-2B PF01008.17 KIK44444.1 - 2.8e-84 282.7 0.1 3.7e-84 282.3 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Presenilin PF01080.17 KIK44444.1 - 0.47 9.2 2.4 0.84 8.3 2.4 1.3 1 0 0 1 1 1 0 Presenilin SOBP PF15279.6 KIK44444.1 - 1.4 9.4 8.5 2.7 8.5 8.5 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Ndc1_Nup PF09531.10 KIK44444.1 - 2 7.0 4.5 2.7 6.6 4.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4551 PF15087.6 KIK44444.1 - 2.9 6.6 7.4 4.5 6.0 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TAF8_C PF10406.9 KIK44446.1 - 6.2e-10 39.5 4.1 6.2e-10 39.5 4.1 2.1 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KIK44446.1 - 3.9e-07 30.0 0.0 5.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Flavokinase PF01687.17 KIK44447.1 - 5.5e-33 113.6 0.0 6.3e-33 113.4 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase Ribosomal_S11 PF00411.19 KIK44448.1 - 1.3e-08 35.2 0.0 3.4e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein S11 UCR_UQCRX_QCR9 PF05365.12 KIK44449.1 - 2.7e-26 91.3 7.2 3e-26 91.1 7.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like IPK PF03770.16 KIK44450.1 - 1.4e-51 175.1 0.0 2.3e-51 174.5 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase CBFB_NFYA PF02045.15 KIK44450.1 - 0.16 12.6 4.8 0.43 11.2 4.8 1.8 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B SLY PF12485.8 KIK44450.1 - 1.3 9.7 6.1 0.14 12.9 0.9 1.9 2 0 0 2 2 2 0 Lymphocyte signaling adaptor protein Forkhead PF00250.18 KIK44452.1 - 2e-27 95.3 0.1 3.3e-27 94.6 0.1 1.3 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KIK44452.1 - 1.2e-06 28.7 0.0 2.5e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain MTP18 PF10558.9 KIK44453.1 - 2.8e-64 216.2 7.1 4.1e-63 212.4 7.1 2.0 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Myb_DNA-binding PF00249.31 KIK44454.1 - 7.1e-51 170.2 12.5 1.3e-15 57.3 0.3 5.6 5 1 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK44454.1 - 1.1e-41 140.9 1.2 1.2e-14 54.2 0.2 5.6 3 2 3 6 6 6 5 Myb-like DNA-binding domain SLIDE PF09111.10 KIK44454.1 - 4.2e-08 33.2 0.0 0.061 13.3 0.0 4.3 2 1 2 4 4 4 2 SLIDE Myb_DNA-bind_4 PF13837.6 KIK44454.1 - 1.8e-07 31.5 10.7 0.08 13.3 0.0 6.1 6 0 0 6 6 6 3 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KIK44454.1 - 0.00012 21.8 0.0 8.4 6.4 0.0 4.1 3 1 1 4 4 4 2 Myb DNA-binding like LEA_5 PF00477.17 KIK44454.1 - 0.017 15.6 0.0 2.3 8.7 0.1 2.5 2 0 0 2 2 2 0 Small hydrophilic plant seed protein Rap1_C PF11626.8 KIK44454.1 - 0.025 14.7 3.0 1.1 9.3 0.1 3.7 2 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.9 KIK44454.1 - 0.69 10.3 8.4 2.9 8.3 0.1 4.8 4 2 2 6 6 6 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TMEM208_SND2 PF05620.11 KIK44455.1 - 1.3e-54 184.5 0.0 1.5e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 LtuB PF17455.2 KIK44455.1 - 0.1 13.2 0.3 0.15 12.7 0.3 1.2 1 0 0 1 1 1 0 Late transcription unit B Mei5 PF10376.9 KIK44456.1 - 0.0055 16.6 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 Double-strand recombination repair protein Abhydrolase_6 PF12697.7 KIK44457.1 - 3.3e-16 60.6 1.2 4.1e-16 60.3 1.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK44457.1 - 1.4e-11 44.1 0.0 2.7e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK44457.1 - 3.7e-10 39.9 0.1 6e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KIK44457.1 - 0.00011 21.2 0.3 0.00043 19.3 0.3 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme LIDHydrolase PF10230.9 KIK44457.1 - 0.0034 17.0 0.0 0.0051 16.4 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase TRAM PF01938.20 KIK44457.1 - 0.008 16.2 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 TRAM domain Chlorophyllase PF07224.11 KIK44457.1 - 0.015 14.3 0.3 0.045 12.8 0.3 1.7 1 1 0 1 1 1 0 Chlorophyllase DLH PF01738.18 KIK44457.1 - 0.033 13.7 0.0 0.087 12.4 0.0 1.8 2 1 1 3 3 3 0 Dienelactone hydrolase family Say1_Mug180 PF10340.9 KIK44457.1 - 0.063 12.1 0.0 0.09 11.6 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase DUF676 PF05057.14 KIK44457.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ser_hydrolase PF06821.13 KIK44457.1 - 0.071 13.0 0.3 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase BAAT_C PF08840.11 KIK44457.1 - 0.13 12.2 0.0 1.6 8.6 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF4406 PF14359.6 KIK44457.1 - 0.18 12.3 0.0 0.5 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4406) Abhydrolase_6 PF12697.7 KIK44458.1 - 6.6e-15 56.3 0.6 8.4e-15 56.0 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK44458.1 - 2.1e-10 40.3 0.0 3.6e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK44458.1 - 2.4e-10 40.5 0.0 2.6e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KIK44458.1 - 0.00037 19.5 0.2 0.0012 17.8 0.2 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme DUF676 PF05057.14 KIK44458.1 - 0.006 16.1 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase PF07224.11 KIK44458.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase FSH1 PF03959.13 KIK44458.1 - 0.048 13.3 0.0 7.8 6.1 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) PGAP1 PF07819.13 KIK44458.1 - 0.066 12.9 1.3 0.96 9.1 0.4 2.4 1 1 1 2 2 2 0 PGAP1-like protein DUF900 PF05990.12 KIK44458.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) DLH PF01738.18 KIK44458.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family PAF-AH_p_II PF03403.13 KIK44458.1 - 0.13 10.8 0.2 3.2 6.2 0.2 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Thioesterase PF00975.20 KIK44458.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF915 PF06028.11 KIK44458.1 - 0.14 11.5 0.1 9.7 5.4 0.0 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) POR PF01558.18 KIK44458.1 - 0.15 12.2 0.1 0.49 10.4 0.0 1.8 2 1 0 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Abhydrolase_6 PF12697.7 KIK44460.1 - 9.3e-13 49.3 0.0 1.1e-12 49.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK44460.1 - 2.9e-12 46.4 0.0 4.3e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK44460.1 - 9.5e-11 41.8 0.0 1.6e-10 41.0 0.0 1.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KIK44460.1 - 9.1e-05 21.5 0.0 0.0004 19.4 0.0 1.9 2 1 0 2 2 2 1 Chlorophyllase enzyme Ser_hydrolase PF06821.13 KIK44460.1 - 0.015 15.1 0.0 0.036 13.9 0.0 1.6 1 1 1 2 2 2 0 Serine hydrolase DLH PF01738.18 KIK44460.1 - 0.029 13.9 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Chlorophyllase PF07224.11 KIK44460.1 - 0.037 13.0 0.0 0.15 11.1 0.0 1.8 1 1 0 1 1 1 0 Chlorophyllase P22_CoatProtein PF11651.8 KIK44460.1 - 0.12 10.9 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 MT-A70 PF05063.14 KIK44461.1 - 4.5e-57 192.7 0.0 6e-57 192.3 0.0 1.2 1 0 0 1 1 1 1 MT-A70 HTH_53 PF18606.1 KIK44461.1 - 0.085 12.5 0.1 4.3 7.1 0.1 2.4 2 0 0 2 2 2 0 Zap helix turn helix N-terminal domain Abhydrolase_6 PF12697.7 KIK44462.1 - 0.0002 22.0 0.0 0.00026 21.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KIK44462.1 - 0.025 14.3 0.0 0.03 14.0 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 KIK44463.1 - 2e-24 86.7 0.0 1.8e-23 83.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK44463.1 - 2.4e-16 59.7 0.0 3.5e-13 49.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIK44463.1 - 5.2e-15 56.6 0.6 1.1e-14 55.6 0.6 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 KIK44463.1 - 0.0006 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase LIDHydrolase PF10230.9 KIK44463.1 - 0.00096 18.8 0.0 0.0021 17.6 0.0 1.5 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Esterase PF00756.20 KIK44463.1 - 0.0025 17.5 0.1 0.0059 16.3 0.1 1.7 1 1 0 1 1 1 1 Putative esterase Ndr PF03096.14 KIK44463.1 - 0.17 10.6 0.0 0.29 9.8 0.0 1.3 1 0 0 1 1 1 0 Ndr family cwf21 PF08312.12 KIK44464.1 - 2.1e-15 56.6 6.2 2.1e-15 56.6 6.2 1.9 2 1 0 2 2 2 1 cwf21 domain Aminotran_3 PF00202.21 KIK44466.1 - 1e-97 327.4 0.0 2e-97 326.4 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KIK44467.1 - 2.1e-73 247.6 0.0 2.9e-73 247.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIK44467.1 - 3.5e-05 22.5 0.0 5.9e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KIK44467.1 - 3.9e-05 22.8 0.0 7.8e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Preseq_ALAS PF09029.10 KIK44467.1 - 0.23 11.9 10.1 8.2 6.9 0.5 2.8 1 1 1 2 2 2 0 5-aminolevulinate synthase presequence Cyto_heme_lyase PF01265.17 KIK44467.1 - 0.31 10.6 1.4 0.53 9.8 1.4 1.3 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase DUF2373 PF10180.9 KIK44468.1 - 1.6e-19 69.5 0.0 2.9e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Arf PF00025.21 KIK44469.1 - 5e-71 237.7 0.0 5.8e-71 237.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KIK44469.1 - 1.8e-15 56.8 0.0 2.5e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KIK44469.1 - 1e-13 51.5 0.0 1.4e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KIK44469.1 - 1.8e-13 50.4 0.1 1.4e-08 34.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KIK44469.1 - 3.8e-10 39.6 0.0 4.1e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KIK44469.1 - 2.2e-09 37.0 0.0 2.7e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIK44469.1 - 0.0003 20.8 0.0 0.0005 20.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOG1 PF06858.14 KIK44469.1 - 0.088 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) WD40 PF00400.32 KIK44472.1 - 1.3e-18 66.9 8.1 0.0007 20.4 0.1 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK44472.1 - 2.3e-08 34.2 0.0 2.6e-07 30.9 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Iso_dh PF00180.20 KIK44473.1 - 2.2e-100 336.2 0.0 2.6e-100 336.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Draxin PF15550.6 KIK44474.1 - 0.23 11.3 34.6 0.57 10.0 23.8 2.6 2 0 0 2 2 2 0 Draxin ATG16 PF08614.11 KIK44475.1 - 0.00068 19.9 8.4 0.00092 19.5 8.4 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 KIK44475.1 - 0.0016 17.9 2.6 0.002 17.5 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF3584 PF12128.8 KIK44475.1 - 0.055 11.0 4.0 0.071 10.6 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FAD-SLDH PF12318.8 KIK44475.1 - 0.13 12.3 4.1 0.076 13.1 1.5 1.8 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase PEP-utilisers_N PF05524.13 KIK44475.1 - 0.15 12.2 1.5 0.27 11.4 1.5 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Macoilin PF09726.9 KIK44475.1 - 0.2 10.2 4.4 0.26 9.8 4.4 1.1 1 0 0 1 1 1 0 Macoilin family YabA PF06156.13 KIK44475.1 - 0.45 11.2 6.1 1.7 9.3 6.1 1.8 1 1 0 1 1 1 0 Initiation control protein YabA DUF1664 PF07889.12 KIK44475.1 - 0.66 10.0 2.6 1 9.4 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 KIK44475.1 - 0.87 7.4 2.8 1.1 7.1 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2992 PF11208.8 KIK44475.1 - 2.6 8.3 6.8 3.2 8.0 5.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2992) TEX13 PF15186.6 KIK44475.1 - 2.9 7.6 9.6 0.56 9.9 4.3 2.0 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family GAS2 PF02187.17 KIK44476.1 - 3.1e-13 49.6 0.0 1e-12 47.9 0.0 1.9 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Borrelia_P83 PF05262.11 KIK44476.1 - 2.8 6.3 31.1 6.8 5.1 31.1 1.6 1 0 0 1 1 1 0 Borrelia P83/100 protein zf-RING_5 PF14634.6 KIK44477.1 - 1.4e-08 34.6 7.9 2.4e-08 33.8 7.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KIK44477.1 - 4.3e-05 23.3 6.7 8.2e-05 22.4 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK44477.1 - 6.5e-05 23.2 7.6 0.00014 22.2 7.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK44477.1 - 9.8e-05 22.1 6.9 0.00019 21.2 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF812 PF05667.11 KIK44477.1 - 0.00011 21.3 3.7 0.00014 20.9 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Prok-RING_4 PF14447.6 KIK44477.1 - 0.00027 20.7 5.6 0.00072 19.4 5.6 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KIK44477.1 - 0.0012 18.7 7.8 0.0022 17.8 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KIK44477.1 - 0.0019 18.1 5.8 0.0036 17.2 5.8 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KIK44477.1 - 0.0024 17.6 1.2 0.0053 16.5 1.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 KIK44477.1 - 0.0026 17.6 0.1 0.0026 17.6 0.1 1.9 2 0 0 2 2 1 1 Prokaryotic RING finger family 1 YkyA PF10368.9 KIK44477.1 - 0.0035 17.0 8.5 0.0048 16.6 8.5 1.1 1 0 0 1 1 1 1 Putative cell-wall binding lipoprotein zf-rbx1 PF12678.7 KIK44477.1 - 0.0065 16.7 3.3 0.014 15.7 3.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-P11 PF03854.14 KIK44477.1 - 0.0085 15.7 2.7 0.017 14.7 2.7 1.5 1 0 0 1 1 1 1 P-11 zinc finger V-ATPase_H_C PF11698.8 KIK44477.1 - 0.011 15.8 2.7 0.019 15.1 2.7 1.3 1 0 0 1 1 1 0 V-ATPase subunit H NleF_casp_inhib PF16809.5 KIK44477.1 - 0.013 15.4 3.8 0.02 14.8 3.8 1.2 1 0 0 1 1 1 0 NleF caspase inhibitor DZR PF12773.7 KIK44477.1 - 0.016 15.2 3.2 0.017 15.1 1.3 1.7 1 1 1 2 2 2 0 Double zinc ribbon EzrA PF06160.12 KIK44477.1 - 0.017 13.3 8.6 0.023 12.9 8.6 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF4472 PF14739.6 KIK44477.1 - 0.02 15.6 6.8 0.033 14.9 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) zf-RING_UBOX PF13445.6 KIK44477.1 - 0.021 14.9 0.5 0.021 14.9 0.5 2.8 3 0 0 3 3 3 0 RING-type zinc-finger Exonuc_VII_L PF02601.15 KIK44477.1 - 0.025 14.1 1.4 0.032 13.8 1.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 KIK44477.1 - 0.031 13.6 4.4 0.045 13.1 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 KIK44477.1 - 0.038 13.5 9.8 0.051 13.0 9.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Phage_GPO PF05929.11 KIK44477.1 - 0.042 13.5 0.7 0.055 13.1 0.7 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3810 PF12725.7 KIK44477.1 - 0.046 13.1 0.4 0.06 12.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF916 PF06030.12 KIK44477.1 - 0.049 13.7 0.1 0.077 13.1 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) SHE3 PF17078.5 KIK44477.1 - 0.052 13.3 8.3 0.078 12.7 8.3 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 HemX PF04375.14 KIK44477.1 - 0.054 12.8 6.4 0.072 12.4 6.4 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase SOGA PF11365.8 KIK44477.1 - 0.06 14.5 9.2 0.36 12.0 0.9 2.2 1 1 1 2 2 2 0 Protein SOGA Spc7 PF08317.11 KIK44477.1 - 0.098 11.5 9.8 0.13 11.1 9.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1272 PF06906.11 KIK44477.1 - 0.1 12.7 6.7 0.24 11.5 6.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zinc_ribbon_11 PF11682.8 KIK44477.1 - 0.12 12.4 0.5 0.12 12.4 0.5 1.7 2 0 0 2 2 1 0 Probable zinc-ribbon Cep57_MT_bd PF06657.13 KIK44477.1 - 0.33 11.4 7.5 3.3 8.2 2.0 2.4 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Ax_dynein_light PF10211.9 KIK44477.1 - 0.4 10.6 11.1 0.59 10.1 11.1 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain zinc-ribbons_6 PF07191.12 KIK44477.1 - 0.44 10.6 5.2 0.92 9.5 5.2 1.6 1 0 0 1 1 1 0 zinc-ribbons Fib_alpha PF08702.10 KIK44477.1 - 0.45 10.7 6.0 0.79 9.9 6.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Fzo_mitofusin PF04799.13 KIK44477.1 - 0.57 9.7 5.9 1 8.9 5.9 1.4 1 0 0 1 1 1 0 fzo-like conserved region PspA_IM30 PF04012.12 KIK44477.1 - 0.71 9.4 12.5 0.99 8.9 12.5 1.1 1 0 0 1 1 1 0 PspA/IM30 family zf-C3HC4_4 PF15227.6 KIK44477.1 - 0.72 10.1 7.3 2 8.7 6.6 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING SlyX PF04102.12 KIK44477.1 - 0.78 10.4 11.3 6.8 7.4 2.2 2.3 1 1 1 2 2 2 0 SlyX DUF1664 PF07889.12 KIK44477.1 - 0.99 9.5 4.5 1.6 8.8 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 KIK44477.1 - 1.1 9.6 10.6 1.6 9.1 10.6 1.2 1 0 0 1 1 1 0 Syntaxin-like protein APG6_N PF17675.1 KIK44477.1 - 1.7 9.1 12.9 0.57 10.7 9.2 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4337 PF14235.6 KIK44477.1 - 2 8.5 6.2 2.9 8.0 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) HIP1_clath_bdg PF16515.5 KIK44477.1 - 2.4 8.8 12.2 3.7 8.2 12.2 1.2 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ADIP PF11559.8 KIK44477.1 - 3 7.9 14.7 9 6.4 14.7 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding BRE1 PF08647.11 KIK44477.1 - 4.6 7.4 14.8 14 5.8 13.2 2.0 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Kinesin PF00225.23 KIK44479.1 - 4.1e-107 358.0 0.0 6.5e-107 357.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KIK44479.1 - 1e-24 87.2 0.0 2.1e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding UPF0242 PF06785.11 KIK44479.1 - 0.18 11.9 0.0 0.41 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus EMP24_GP25L PF01105.24 KIK44480.1 - 5.4e-51 173.1 1.2 6.6e-51 172.8 1.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ran_BP1 PF00638.18 KIK44481.1 - 1e-49 167.8 1.3 1.6e-49 167.2 1.3 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 KIK44481.1 - 0.00051 19.9 0.3 0.0031 17.4 0.3 1.9 1 1 0 1 1 1 1 WH1 domain GOLD_2 PF13897.6 KIK44481.1 - 0.69 10.4 7.0 3.1 8.3 4.1 2.1 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking NOA36 PF06524.12 KIK44481.1 - 4.2 6.6 9.9 6.3 6.0 9.9 1.2 1 0 0 1 1 1 0 NOA36 protein AAA_2 PF07724.14 KIK44482.1 - 7e-38 130.4 0.0 1.1e-37 129.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KIK44482.1 - 1.1e-14 55.0 0.0 2.7e-14 53.7 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KIK44482.1 - 3.9e-10 39.6 0.0 9.9e-10 38.3 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KIK44482.1 - 3.7e-06 27.0 0.0 2.1e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIK44482.1 - 1.4e-05 25.3 0.1 0.00034 20.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KIK44482.1 - 0.00033 20.1 0.0 0.005 16.3 0.0 2.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KIK44482.1 - 0.0013 19.2 0.0 0.0035 17.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KIK44482.1 - 0.0029 18.1 0.0 0.017 15.7 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_3 PF07726.11 KIK44482.1 - 0.0075 16.1 0.1 0.17 11.8 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KIK44482.1 - 0.0079 15.9 0.0 0.033 13.9 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein T2SSE PF00437.20 KIK44482.1 - 0.01 14.9 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 KIK44482.1 - 0.01 15.5 0.0 0.096 12.4 0.0 2.3 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KIK44482.1 - 0.012 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KIK44482.1 - 0.012 16.0 0.0 0.038 14.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KIK44482.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 KIK44482.1 - 0.013 14.6 0.0 0.035 13.2 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain AAA_24 PF13479.6 KIK44482.1 - 0.019 14.7 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KIK44482.1 - 0.019 14.7 0.1 0.13 12.0 0.0 2.2 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain PhoH PF02562.16 KIK44482.1 - 0.023 14.1 0.0 0.061 12.8 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 KIK44482.1 - 0.024 14.7 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 KIK44482.1 - 0.024 14.8 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 KIK44482.1 - 0.054 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DEAD PF00270.29 KIK44482.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.5 2 0 0 2 2 1 0 DEAD/DEAH box helicase AAA_29 PF13555.6 KIK44482.1 - 0.067 13.0 0.0 0.44 10.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KIK44482.1 - 0.088 13.4 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KIK44482.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 KIK44482.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family HAMP PF00672.25 KIK44483.1 - 4.2e-44 148.7 19.3 1.8e-08 34.7 0.0 8.7 8 1 0 8 8 8 7 HAMP domain HisKA PF00512.25 KIK44483.1 - 1.3e-17 63.6 1.1 6.8e-17 61.3 1.1 2.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF4795 PF16043.5 KIK44483.1 - 5.8e-06 26.1 0.9 0.064 12.9 0.0 4.1 3 1 1 4 4 4 2 Domain of unknown function (DUF4795) DUF3829 PF12889.7 KIK44483.1 - 0.2 11.1 2.5 19 4.6 0.0 4.0 4 3 2 6 6 6 0 Protein of unknown function (DUF3829) SpoIIID PF12116.8 KIK44483.1 - 0.6 10.2 4.8 48 4.1 0.0 4.8 5 0 0 5 5 5 0 Stage III sporulation protein D DUF948 PF06103.11 KIK44483.1 - 1.5 9.2 49.3 0.18 12.1 1.6 10.4 3 2 4 7 7 7 0 Bacterial protein of unknown function (DUF948) AcylCoA_dehyd_C PF12186.8 KIK44483.1 - 2.3 8.4 12.4 1e+02 3.1 0.1 6.7 7 1 1 8 8 8 0 Acyl-CoA dehydrogenase C terminal T4SS PF07996.11 KIK44483.1 - 3.8 7.9 13.1 4.8 7.5 0.2 3.9 3 1 1 4 4 4 0 Type IV secretion system proteins V-ATPase_H_C PF11698.8 KIK44483.1 - 7.3 6.7 7.1 5 7.3 0.3 3.8 4 0 0 4 4 4 0 V-ATPase subunit H PLDc PF00614.22 KIK44485.1 - 1.4e-16 59.8 2.8 5.7e-08 32.6 0.2 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KIK44485.1 - 2.9e-16 59.6 0.1 1.4e-06 28.3 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain Gti1_Pac2 PF09729.9 KIK44488.1 - 1.5e-57 194.6 0.0 6.1e-57 192.6 0.0 1.9 2 0 0 2 2 2 1 Gti1/Pac2 family WSC PF01822.19 KIK44489.1 - 1.5e-67 223.8 67.3 4.1e-18 65.4 12.1 4.3 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.11 KIK44489.1 - 1.3e-30 106.4 0.0 4.2e-29 101.4 0.0 2.5 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KIK44489.1 - 5.1e-19 68.4 0.0 1.4e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) DUF5122 PF17164.4 KIK44489.1 - 0.0091 16.3 0.9 42 4.6 0.0 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller Kelch_2 PF07646.15 KIK44489.1 - 0.41 10.7 0.0 0.41 10.7 0.0 4.5 5 0 0 5 5 5 0 Kelch motif PAN_3 PF08277.12 KIK44489.1 - 3 7.7 26.0 2.3 8.1 0.7 4.8 4 1 0 4 4 4 0 PAN-like domain SAC3_GANP PF03399.16 KIK44491.1 - 5.1e-63 213.2 0.1 1.1e-62 212.1 0.1 1.5 1 0 0 1 1 1 1 SAC3/GANP family Fer4_17 PF13534.6 KIK44491.1 - 0.19 12.3 0.2 0.61 10.7 0.1 1.9 2 0 0 2 2 2 0 4Fe-4S dicluster domain FHA PF00498.26 KIK44492.1 - 9.3e-10 38.7 0.1 2e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 FHA domain HsbA PF12296.8 KIK44492.1 - 0.024 15.1 3.2 0.067 13.6 0.5 2.4 1 1 1 2 2 2 0 Hydrophobic surface binding protein A XhlA PF10779.9 KIK44492.1 - 0.078 13.2 0.3 0.078 13.2 0.3 2.8 2 1 0 3 3 3 0 Haemolysin XhlA SF-assemblin PF06705.11 KIK44492.1 - 0.087 12.2 8.5 2.4 7.4 0.1 2.5 1 1 0 2 2 2 0 SF-assemblin/beta giardin Leu_zip PF15294.6 KIK44492.1 - 0.36 10.3 5.9 0.59 9.6 5.9 1.3 1 0 0 1 1 1 0 Leucine zipper NPV_P10 PF05531.12 KIK44492.1 - 0.36 11.3 8.3 3.4e+02 1.8 8.3 3.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein EzrA PF06160.12 KIK44492.1 - 0.41 8.8 5.5 0.07 11.3 1.1 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF4795 PF16043.5 KIK44492.1 - 0.45 10.1 6.8 0.82 9.2 6.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Spectrin PF00435.21 KIK44492.1 - 0.45 11.0 4.6 1.9 9.0 2.3 2.7 1 1 2 3 3 3 0 Spectrin repeat DUF2730 PF10805.8 KIK44492.1 - 0.5 10.5 2.5 3.3 7.9 0.4 2.8 2 1 1 3 3 2 0 Protein of unknown function (DUF2730) FUSC PF04632.12 KIK44492.1 - 0.63 8.5 4.0 0.4 9.2 2.4 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family Laminin_II PF06009.12 KIK44492.1 - 0.73 9.8 6.7 0.18 11.8 1.3 2.2 1 1 0 2 2 2 0 Laminin Domain II TMF_TATA_bd PF12325.8 KIK44492.1 - 0.77 10.0 9.9 0.22 11.8 1.0 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Baculo_PEP_C PF04513.12 KIK44492.1 - 0.77 9.8 4.9 74 3.4 4.9 2.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 KIK44492.1 - 0.88 10.0 3.8 7.6 7.0 0.3 3.2 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Syntaxin-6_N PF09177.11 KIK44492.1 - 0.93 10.1 5.1 0.88 10.2 1.1 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 KIK44492.1 - 1.8 8.6 4.8 0.39 10.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KIK44492.1 - 3.2 8.1 5.3 1.2 9.5 0.9 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.7 KIK44492.1 - 3.5 7.8 11.4 0.18 12.0 2.5 2.3 2 0 0 2 2 2 0 Tropomyosin like Pkinase PF00069.25 KIK44493.1 - 1.6e-70 237.5 0.0 2e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK44493.1 - 1.9e-30 106.0 0.0 2.5e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK44493.1 - 0.0002 20.5 0.4 0.001 18.1 0.4 1.9 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIK44493.1 - 0.0036 17.2 0.1 0.0079 16.1 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK44493.1 - 0.02 14.2 0.0 0.27 10.5 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 KIK44493.1 - 0.025 13.7 0.0 0.088 11.8 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 ATP_bind_1 PF03029.17 KIK44495.1 - 2.5e-74 250.1 0.0 3.2e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KIK44495.1 - 7.8e-05 22.3 0.0 0.018 14.6 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIK44495.1 - 0.00028 20.8 0.0 0.19 11.6 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase AAA_33 PF13671.6 KIK44495.1 - 0.0011 19.2 0.0 0.0023 18.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 KIK44495.1 - 0.0012 17.9 0.0 1 8.3 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KIK44495.1 - 0.0013 18.8 0.0 0.007 16.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 KIK44495.1 - 0.0034 17.3 0.0 0.0061 16.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 KIK44495.1 - 0.0053 16.5 0.0 0.021 14.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KIK44495.1 - 0.0065 16.4 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 1 NTPase cobW PF02492.19 KIK44495.1 - 0.023 14.3 0.1 0.45 10.1 0.1 2.4 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 KIK44495.1 - 0.026 14.0 0.0 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B SRP54 PF00448.22 KIK44495.1 - 0.034 13.8 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain G-alpha PF00503.20 KIK44495.1 - 0.037 13.2 0.0 1.2 8.2 0.0 2.4 3 0 0 3 3 3 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 KIK44495.1 - 0.039 13.3 0.1 1.6 8.0 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family PAPA-1 PF04795.12 KIK44495.1 - 0.058 14.2 0.3 0.12 13.1 0.3 1.5 1 0 0 1 1 1 0 PAPA-1-like conserved region NB-ARC PF00931.22 KIK44495.1 - 0.072 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Roc PF08477.13 KIK44495.1 - 0.14 12.4 0.0 11 6.3 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 KIK44495.1 - 0.15 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KIK44495.1 - 0.15 11.3 0.0 0.33 10.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 KIK44495.1 - 0.17 12.3 0.0 0.64 10.4 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain DUF4611 PF15387.6 KIK44495.1 - 0.21 11.8 2.2 0.45 10.8 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF1634 PF07843.11 KIK44497.1 - 0.013 15.5 0.3 0.028 14.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) DUF4097 PF13349.6 KIK44501.1 - 0.00047 19.6 7.8 0.01 15.2 7.8 2.6 1 1 0 1 1 1 1 Putative adhesin DUF603 PF04645.12 KIK44501.1 - 0.13 12.0 0.7 0.26 11.0 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF603 LSM PF01423.22 KIK44502.1 - 1e-16 60.4 0.0 1.6e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIK44502.1 - 0.17 12.0 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain OPT PF03169.15 KIK44503.1 - 2.9e-185 617.5 48.4 3.4e-185 617.2 48.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2263 PF10021.9 KIK44512.1 - 8.7e-41 139.7 0.0 1.2e-40 139.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) ArsB PF02040.15 KIK44512.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Arsenical pump membrane protein BTB PF00651.31 KIK44513.1 - 9.6e-07 29.0 0.0 1.8e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain SOG2 PF10428.9 KIK44513.1 - 0.011 15.0 15.5 0.012 14.8 15.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GREB1 PF15782.5 KIK44513.1 - 3.1 4.8 9.6 3.6 4.6 9.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer BTB PF00651.31 KIK44514.1 - 5.3e-06 26.6 0.0 9.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF5321 PF17254.2 KIK44515.1 - 0.017 14.6 0.6 0.039 13.4 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5321) PBECR1 PF18809.1 KIK44515.1 - 0.12 13.0 0.9 1.3 9.7 0.1 2.2 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 Glyco_hydro_28 PF00295.17 KIK44517.1 - 1.6e-58 198.3 15.0 2.1e-58 198.0 15.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Hydrolase_4 PF12146.8 KIK44518.1 - 2.2e-59 200.6 0.0 2.6e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIK44518.1 - 1.1e-17 65.4 0.1 1.5e-17 65.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK44518.1 - 3.6e-13 49.7 0.1 6e-09 35.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KIK44518.1 - 5.9e-06 26.2 0.1 0.14 12.0 0.1 3.2 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DLH PF01738.18 KIK44518.1 - 0.00011 21.9 0.0 0.12 11.9 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 KIK44518.1 - 0.00017 20.6 0.0 0.00056 18.9 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 KIK44518.1 - 0.0002 20.9 0.1 0.16 11.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 KIK44518.1 - 0.00041 19.1 0.1 0.015 13.9 0.1 2.7 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) PGAP1 PF07819.13 KIK44518.1 - 0.00083 19.1 0.0 0.053 13.2 0.0 2.6 3 0 0 3 3 3 1 PGAP1-like protein Abhydrolase_3 PF07859.13 KIK44518.1 - 0.0029 17.5 0.0 0.0055 16.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KIK44518.1 - 0.005 17.0 0.8 0.015 15.4 0.2 2.0 2 1 1 3 3 3 1 Thioesterase domain Lipase_3 PF01764.25 KIK44518.1 - 0.0051 16.7 0.0 0.0078 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) FSH1 PF03959.13 KIK44518.1 - 0.0072 16.0 0.0 0.022 14.4 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.20 KIK44518.1 - 0.033 13.8 0.1 0.13 11.8 0.1 2.0 1 1 0 1 1 1 0 Putative esterase DUF900 PF05990.12 KIK44518.1 - 0.07 12.6 0.3 0.98 8.9 0.3 2.4 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.11 KIK44518.1 - 0.081 12.2 0.0 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.7 KIK44518.1 - 0.11 12.2 0.0 18 5.1 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Clathrin_lg_ch PF01086.17 KIK44519.1 - 1.3e-42 146.5 0.1 1.4e-42 146.3 0.1 1.1 1 0 0 1 1 1 1 Clathrin light chain Hydrolase_3 PF08282.12 KIK44519.1 - 0.16 11.7 0.2 0.21 11.3 0.2 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase LysM PF01476.20 KIK44519.1 - 0.2 11.7 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 LysM domain Ribosomal_L30_N PF08079.12 KIK44519.1 - 2.1 8.7 10.0 4 7.8 10.0 1.4 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain PGP_phosphatase PF09419.10 KIK44520.1 - 9.3e-46 155.5 0.0 1.2e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KIK44520.1 - 0.058 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Glyco_hydro_18 PF00704.28 KIK44521.1 - 4.7e-47 161.2 0.3 5.5e-47 161.0 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ABC_membrane PF00664.23 KIK44523.1 - 2.7e-52 178.1 1.8 3.7e-52 177.7 1.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KIK44523.1 - 1e-29 103.8 0.0 2.7e-29 102.4 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIK44523.1 - 0.00076 19.0 1.4 0.01 15.3 0.0 2.2 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KIK44523.1 - 0.012 15.0 0.0 0.039 13.2 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 KIK44523.1 - 0.76 10.1 4.9 0.49 10.8 0.7 2.8 3 1 0 3 3 3 0 AAA ATPase domain Holin_SPP1 PF04688.13 KIK44524.1 - 0.03 14.5 0.1 0.03 14.5 0.1 2.7 2 0 0 2 2 2 0 SPP1 phage holin DUF621 PF04789.15 KIK44524.1 - 0.034 13.3 4.3 0.072 12.2 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF621) PetG PF02529.15 KIK44524.1 - 0.72 9.7 4.3 0.85 9.5 2.8 1.9 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 DUF5362 PF17319.2 KIK44524.1 - 1.8 8.5 4.6 1.6 8.6 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5362) SUR7 PF06687.12 KIK44527.1 - 1.5e-09 37.8 20.5 1.9e-09 37.5 20.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family Polyoma_coat2 PF00761.20 KIK44527.1 - 0.13 11.9 3.0 0.17 11.5 3.0 1.1 1 0 0 1 1 1 0 Polyomavirus coat protein Chordopox_A33R PF05966.12 KIK44527.1 - 5.1 6.3 7.3 5.3 6.3 1.7 2.9 3 0 0 3 3 3 0 Chordopoxvirus A33R protein SUV3_C PF12513.8 KIK44529.1 - 0.059 13.3 0.2 0.078 12.9 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal Foie-gras_1 PF11817.8 KIK44532.1 - 8e-37 127.2 6.5 1.3e-34 120.0 4.8 3.0 2 1 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.12 KIK44532.1 - 5.8e-18 65.0 0.0 1.3e-12 47.3 0.0 2.2 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 KIK44532.1 - 8.1e-06 25.7 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking TPR_12 PF13424.6 KIK44532.1 - 0.0014 18.8 3.4 0.008 16.4 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TRAPPC10 PF12584.8 KIK44532.1 - 0.032 13.9 0.0 0.069 12.8 0.0 1.6 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_2 PF07719.17 KIK44532.1 - 0.62 10.3 4.3 0.77 10.0 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat GST_N_3 PF13417.6 KIK44533.1 - 6.1e-20 71.4 0.0 1.2e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK44533.1 - 1.2e-17 64.0 0.1 2.8e-17 62.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK44533.1 - 1.5e-10 41.2 0.4 4.8e-10 39.6 0.2 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KIK44533.1 - 0.00012 22.6 0.0 0.00025 21.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIK44533.1 - 0.0013 18.9 0.1 0.0055 16.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK44533.1 - 0.0016 18.4 0.1 0.0056 16.7 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KIK44533.1 - 0.065 14.0 0.0 0.13 13.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Plavaka PF18759.1 KIK44534.1 - 0.048 12.9 0.0 0.062 12.5 0.0 1.1 1 0 0 1 1 1 0 Plavaka transposase Metallophos PF00149.28 KIK44535.1 - 1.3e-11 45.4 0.1 1.8e-11 44.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NAD_binding_10 PF13460.6 KIK44537.1 - 2.2e-07 30.9 0.9 6.4e-07 29.4 0.0 2.0 3 0 0 3 3 3 1 NAD(P)H-binding NmrA PF05368.13 KIK44537.1 - 1.1e-06 28.4 0.1 1.4e-05 24.8 0.0 2.3 1 1 1 2 2 2 1 NmrA-like family PAC2 PF09754.9 KIK44537.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 PAC2 family DUF836 PF05768.14 KIK44538.1 - 4.6e-11 43.0 0.0 8.1e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) PSP PF04046.16 KIK44538.1 - 6e-05 22.8 0.1 0.00017 21.4 0.1 1.8 1 0 0 1 1 1 1 PSP Thioredoxin_3 PF13192.6 KIK44538.1 - 0.0022 18.0 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain zf-CCHC PF00098.23 KIK44538.1 - 0.0046 17.0 1.1 0.0097 16.0 1.1 1.6 1 0 0 1 1 1 1 Zinc knuckle TraF PF13728.6 KIK44538.1 - 0.081 12.7 0.0 0.081 12.7 0.0 1.7 2 0 0 2 2 2 0 F plasmid transfer operon protein Mito_fiss_reg PF05308.11 KIK44538.1 - 4.6 7.2 6.7 8.4 6.4 6.7 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator AAA_5 PF07728.14 KIK44539.1 - 2.6e-10 40.5 0.0 4.9e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIK44539.1 - 9.4e-06 25.8 0.0 2.1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) zf_CCCH_4 PF18345.1 KIK44539.1 - 2.9e-05 23.9 1.6 6.2e-05 22.9 1.6 1.6 1 0 0 1 1 1 1 Zinc finger domain AAA PF00004.29 KIK44539.1 - 6.3e-05 23.4 0.0 0.00013 22.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK44539.1 - 8.5e-05 22.8 0.1 0.00045 20.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain zf-CCCH_4 PF18044.1 KIK44539.1 - 9.5e-05 22.1 2.0 0.00017 21.3 2.0 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger AAA_16 PF13191.6 KIK44539.1 - 0.00013 22.4 0.3 0.042 14.2 0.1 3.2 2 1 1 3 3 3 1 AAA ATPase domain zf-CCCH PF00642.24 KIK44539.1 - 0.00073 19.4 0.9 0.0013 18.6 0.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_PrkA PF08298.11 KIK44539.1 - 0.0077 15.2 0.0 0.019 13.9 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain Torus PF16131.5 KIK44539.1 - 0.023 15.4 0.1 0.044 14.5 0.1 1.4 1 0 0 1 1 1 0 Torus domain RNA_helicase PF00910.22 KIK44539.1 - 0.028 14.8 0.0 0.073 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KIK44539.1 - 0.03 14.4 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KIK44539.1 - 0.067 12.6 0.0 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF4381 PF14316.6 KIK44541.1 - 0.077 13.2 0.4 0.72 10.1 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Pam17 PF08566.10 KIK44542.1 - 3.5e-64 215.6 0.0 4.2e-64 215.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 SNF2_N PF00176.23 KIK44543.1 - 1.1e-47 162.4 0.0 7.6e-40 136.7 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK44543.1 - 3.9e-09 36.8 0.0 7.9e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TetR_C_3 PF08362.11 KIK44543.1 - 0.11 12.4 0.0 0.52 10.3 0.0 2.1 2 0 0 2 2 2 0 YcdC-like protein, C-terminal region MCM PF00493.23 KIK44544.1 - 9.6e-106 351.9 0.0 1.5e-105 351.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KIK44544.1 - 1.3e-29 102.6 0.5 2e-29 102.0 0.5 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KIK44544.1 - 1.2e-19 70.5 1.7 2.9e-19 69.3 1.7 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KIK44544.1 - 4.7e-19 68.9 0.1 1.5e-18 67.3 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KIK44544.1 - 5.3e-08 32.5 0.1 1.1e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KIK44544.1 - 7.4e-08 32.5 0.0 4.8e-06 26.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase_C PF13335.6 KIK44544.1 - 0.00023 21.8 0.9 0.00023 21.8 0.9 2.3 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 KIK44544.1 - 0.02 14.7 0.0 0.07 13.0 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 KIK44544.1 - 0.044 13.6 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 AAA lid domain PI-TkoII_IV PF18714.1 KIK44544.1 - 0.065 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV Sigma54_activat PF00158.26 KIK44544.1 - 0.14 11.8 0.1 0.71 9.6 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain Transp_cyt_pur PF02133.15 KIK44545.1 - 5.7e-28 97.9 27.1 8.4e-28 97.3 27.1 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin YqhR PF11085.8 KIK44545.1 - 3.3 7.6 7.3 0.71 9.8 2.5 2.3 2 0 0 2 2 2 0 Conserved membrane protein YqhR MTHFR PF02219.17 KIK44547.1 - 1.2e-104 349.6 0.0 1.8e-104 349.1 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Saf-Nte_pilin PF09460.10 KIK44547.1 - 0.066 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Saf-pilin pilus formation protein Ras PF00071.22 KIK44548.1 - 4.5e-59 198.7 0.4 6.5e-59 198.2 0.4 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK44548.1 - 8.6e-38 129.2 0.1 1.7e-37 128.3 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK44548.1 - 6.4e-16 58.3 0.2 8.1e-16 58.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KIK44548.1 - 4.9e-07 29.4 0.1 7.3e-07 28.8 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KIK44548.1 - 2.9e-06 26.9 0.4 3.2e-05 23.6 0.4 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIK44548.1 - 2.2e-05 24.5 0.1 9.7e-05 22.4 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KIK44548.1 - 3.2e-05 23.4 0.6 4.6e-05 22.9 0.6 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KIK44548.1 - 8.6e-05 22.5 0.1 0.025 14.5 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KIK44548.1 - 0.00026 20.6 0.6 0.018 14.6 0.6 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B TniB PF05621.11 KIK44548.1 - 0.041 13.3 0.1 0.22 10.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein Dynamin_N PF00350.23 KIK44548.1 - 0.06 13.4 0.1 2.4 8.2 0.0 2.6 2 1 1 3 3 3 0 Dynamin family PduV-EutP PF10662.9 KIK44548.1 - 0.065 13.0 2.1 0.43 10.3 2.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation CPT PF07931.12 KIK44548.1 - 0.066 13.1 0.0 0.13 12.0 0.0 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_7 PF12775.7 KIK44548.1 - 0.072 12.6 0.2 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 KIK44548.1 - 0.14 12.5 0.0 0.46 10.8 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain TAP42 PF04177.12 KIK44549.1 - 5.4e-91 305.0 3.9 6.2e-91 304.8 3.9 1.0 1 0 0 1 1 1 1 TAP42-like family DUF2175 PF09943.9 KIK44549.1 - 1.5 9.1 3.9 0.78 10.1 0.3 2.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) POT1PC PF16686.5 KIK44550.1 - 1.3e-11 44.6 2.6 3.2e-05 23.9 0.5 4.5 3 2 0 3 3 3 2 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KIK44550.1 - 1.2e-06 28.5 0.0 2.5e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 YL1 PF05764.13 KIK44550.1 - 0.29 11.2 6.2 0.5 10.4 6.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF4813 PF16072.5 KIK44550.1 - 3.3 7.3 9.8 0.23 11.1 4.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) HTH_23 PF13384.6 KIK44552.1 - 2e-07 30.6 0.0 6.5e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KIK44552.1 - 7.9e-06 25.9 0.0 3.4e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_33 PF13592.6 KIK44552.1 - 2.1e-05 24.1 0.0 6.4e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 KIK44552.1 - 6.4e-05 23.5 0.0 0.00046 20.7 0.0 2.1 1 1 1 2 2 2 1 Homeodomain-like domain Terminase_5 PF06056.12 KIK44552.1 - 0.00017 21.4 0.0 0.00027 20.8 0.0 1.4 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_29 PF13551.6 KIK44552.1 - 0.023 14.7 0.3 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix POT1 PF02765.17 KIK44553.1 - 2.4e-15 56.6 0.0 6.6e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 POT1PC PF16686.5 KIK44553.1 - 7e-12 45.5 3.2 0.00028 20.8 0.3 5.4 3 2 0 3 3 3 2 ssDNA-binding domain of telomere protection protein Macoilin PF09726.9 KIK44553.1 - 2.9 6.4 4.7 4.2 5.8 4.7 1.1 1 0 0 1 1 1 0 Macoilin family TMEM108 PF15759.5 KIK44554.1 - 0.062 12.3 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 TMEM108 family TrpP PF17099.5 KIK44555.1 - 0.061 13.1 0.3 0.098 12.4 0.0 1.5 2 0 0 2 2 2 0 Tryptophan transporter TrpP WD40 PF00400.32 KIK44556.1 - 5.5e-09 36.5 0.1 0.00094 20.0 0.0 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.32 KIK44558.1 - 0.00022 21.9 1.3 0.02 15.8 0.0 3.9 5 0 0 5 5 5 1 WD domain, G-beta repeat bZIP_1 PF00170.21 KIK44558.1 - 0.026 14.6 0.6 0.069 13.3 0.6 1.7 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 KIK44558.1 - 0.036 14.2 3.6 0.12 12.5 3.6 1.9 1 0 0 1 1 1 0 Basic region leucine zipper PikAIV_N PF18605.1 KIK44558.1 - 0.88 9.2 8.8 1.8 8.2 8.8 1.5 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain ZapB PF06005.12 KIK44558.1 - 2.4 8.7 5.5 0.25 11.8 0.9 1.7 2 0 0 2 2 2 0 Cell division protein ZapB VRR_NUC PF08774.11 KIK44559.1 - 6.3e-21 74.5 0.0 1.3e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain TFIIF_alpha PF05793.12 KIK44559.1 - 0.01 14.5 7.6 0.022 13.4 7.6 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MAGI_u5 PF16666.5 KIK44559.1 - 3.9 7.7 11.4 0.1 12.7 3.7 2.3 2 0 0 2 2 2 0 Unstructured region on MAGI PhoLip_ATPase_C PF16212.5 KIK44563.1 - 7.6e-71 238.8 31.4 7.6e-71 238.8 31.4 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KIK44563.1 - 1.5e-22 79.0 1.5 3.8e-22 77.7 1.5 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KIK44563.1 - 6.9e-12 46.1 7.6 1.4e-07 32.0 2.3 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIK44563.1 - 2.6e-11 43.4 0.0 5.4e-10 39.2 0.0 2.7 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KIK44563.1 - 0.00038 20.3 1.2 0.0063 16.3 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KIK44563.1 - 0.013 15.0 3.9 0.026 14.1 0.0 2.8 2 0 0 2 2 2 0 E1-E2 ATPase Septin PF00735.18 KIK44564.1 - 9.4e-114 379.4 1.2 1.1e-113 379.2 1.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KIK44564.1 - 3.7e-08 33.4 0.4 2e-07 31.1 0.4 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK44564.1 - 1.5e-06 27.7 0.0 2.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KIK44564.1 - 1.8e-06 28.0 0.5 4.6e-05 23.4 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KIK44564.1 - 2.1e-05 24.1 0.2 0.001 18.6 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KIK44564.1 - 0.00015 21.9 0.9 0.32 11.1 0.2 2.4 1 1 1 2 2 2 2 Dynamin family NB-ARC PF00931.22 KIK44564.1 - 0.00087 18.5 0.0 0.0015 17.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KIK44564.1 - 0.0024 18.3 0.0 0.0048 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KIK44564.1 - 0.0036 17.8 0.2 0.0081 16.7 0.1 1.6 1 1 0 1 1 1 1 ABC transporter Gtr1_RagA PF04670.12 KIK44564.1 - 0.0037 16.7 0.3 0.01 15.2 0.3 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region T2SSE PF00437.20 KIK44564.1 - 0.0053 15.9 0.1 0.01 14.9 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KIK44564.1 - 0.0057 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.6 KIK44564.1 - 0.011 16.1 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK44564.1 - 0.023 14.2 0.3 0.08 12.5 0.1 1.9 1 1 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 KIK44564.1 - 0.035 13.9 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.22 KIK44564.1 - 0.039 13.6 0.3 0.17 11.5 0.1 2.1 2 0 0 2 2 2 0 Ras family Roc PF08477.13 KIK44564.1 - 0.047 13.9 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 KIK44564.1 - 0.078 12.0 1.1 0.15 11.1 0.1 1.9 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) AAA_14 PF13173.6 KIK44564.1 - 0.083 12.9 0.2 0.45 10.6 0.1 2.3 2 1 0 2 2 2 0 AAA domain Aha1_N PF09229.11 KIK44565.1 - 5.4e-31 107.6 0.0 7.9e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KIK44565.1 - 2.3e-13 50.5 0.0 5.3e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DUF3429 PF11911.8 KIK44566.1 - 4.2e-40 137.4 13.8 5.8e-40 136.9 13.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) WD40 PF00400.32 KIK44567.1 - 2.5e-24 85.1 13.0 0.00023 21.9 0.0 8.1 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KIK44567.1 - 5.8e-14 51.7 2.2 1.3e-13 50.6 2.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK44567.1 - 1.8e-09 37.3 0.5 3.8e-09 36.2 0.5 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KIK44567.1 - 0.0076 14.9 0.0 9.6 4.7 0.0 3.2 3 0 0 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK44567.1 - 0.056 12.8 0.0 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 WD40-like domain ANAPC4_WD40 PF12894.7 KIK44567.1 - 0.067 13.5 0.1 6.6 7.1 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK44568.1 - 3.7e-34 116.2 6.5 6.7e-05 23.6 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK44568.1 - 4.7e-10 39.6 0.0 0.22 11.8 0.0 6.1 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK44568.1 - 2.3e-06 26.8 0.5 0.66 8.9 0.0 4.7 2 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK44568.1 - 0.018 15.0 0.2 13 5.8 0.0 4.7 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KIK44568.1 - 0.021 13.4 0.0 1.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nup160 PF11715.8 KIK44568.1 - 0.094 11.3 0.0 0.87 8.1 0.0 2.3 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK44568.1 - 0.13 11.6 0.0 28 3.9 0.0 3.0 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Peptidase_S8 PF00082.22 KIK44569.1 - 8.6e-37 127.0 0.9 1.3e-36 126.4 0.9 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KIK44569.1 - 1e-30 105.5 0.9 2.3e-30 104.5 0.9 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain DNA_methylase PF00145.17 KIK44570.1 - 9.7e-54 182.9 0.0 3.9e-53 180.9 0.0 2.0 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 KIK44570.1 - 2.4e-17 62.9 0.4 2.1e-08 34.1 0.1 2.6 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.8 KIK44570.1 - 8e-09 35.7 0.0 1.9e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain p450 PF00067.22 KIK44571.1 - 1.8e-53 182.0 0.0 2.2e-52 178.4 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIK44576.1 - 3.6e-52 177.7 0.0 2.4e-25 89.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DGF-1_4 PF11024.8 KIK44577.1 - 0.0026 18.5 0.9 0.0039 18.0 0.9 1.2 1 0 0 1 1 1 1 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 WD40 PF00400.32 KIK44579.1 - 3.3e-21 75.2 9.5 7.5e-09 36.1 0.1 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KIK44579.1 - 8.3e-05 21.5 1.2 0.0064 15.3 0.0 2.8 1 1 2 3 3 3 1 Nup133 N terminal like ANAPC4_WD40 PF12894.7 KIK44579.1 - 0.00028 21.1 0.1 1.4 9.2 0.0 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK44579.1 - 0.00065 18.7 0.1 0.037 13.0 0.0 2.1 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK44579.1 - 0.016 15.2 0.2 0.66 10.0 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat p450 PF00067.22 KIK44580.1 - 2.7e-33 115.4 0.0 3.1e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DFF-C PF09033.10 KIK44580.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain Na_trans_assoc PF06512.13 KIK44582.1 - 0.00059 20.2 6.8 0.00071 19.9 6.8 1.2 1 0 0 1 1 1 1 Sodium ion transport-associated ZapB PF06005.12 KIK44582.1 - 0.061 13.8 1.0 0.15 12.5 1.0 1.6 1 1 0 1 1 1 0 Cell division protein ZapB WD40 PF00400.32 KIK44583.1 - 1.4e-09 38.4 9.5 0.0027 18.5 0.1 5.9 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK44583.1 - 0.00076 19.7 0.0 0.16 12.2 0.0 2.9 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KIK44583.1 - 0.011 14.3 0.0 0.051 12.1 0.0 1.9 1 1 0 1 1 1 0 Cytochrome D1 heme domain YpsA PF06908.11 KIK44583.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family Transket_pyr PF02779.24 KIK44584.1 - 2.8e-38 131.4 0.0 4e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KIK44584.1 - 3.5e-23 81.8 0.0 1.1e-22 80.3 0.0 1.8 1 1 0 1 1 1 1 Transketolase, C-terminal domain WD40 PF00400.32 KIK44585.1 - 1.2e-14 54.4 4.5 0.00023 21.9 0.1 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Homeodomain PF00046.29 KIK44588.1 - 2.2e-14 53.0 0.2 6.2e-14 51.6 0.2 1.7 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KIK44588.1 - 0.00031 20.6 0.0 0.0046 16.8 0.1 2.8 3 0 0 3 3 3 1 Homeobox KN domain HTH_3 PF01381.22 KIK44588.1 - 0.048 13.7 0.0 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix HOCHOB PF17943.1 KIK44588.1 - 0.05 14.3 0.0 0.097 13.4 0.0 1.4 1 0 0 1 1 1 0 Homeobox-cysteine loop-homeobox YdaS_antitoxin PF15943.5 KIK44588.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT zf-SNAP50_C PF12251.8 KIK44589.1 - 1.1e-30 106.8 0.0 1.5e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal NAD_binding_5 PF07994.12 KIK44591.1 - 6.2e-139 462.9 0.0 7.6e-139 462.6 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KIK44591.1 - 4.8e-45 152.3 0.0 9.9e-45 151.3 0.0 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase ERO1 PF04137.15 KIK44592.1 - 1.1e-127 426.1 0.0 1.4e-127 425.8 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF349 PF03993.12 KIK44592.1 - 0.078 13.3 0.4 0.2 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) p450 PF00067.22 KIK44595.1 - 3.1e-56 191.1 0.0 1.3e-54 185.7 0.0 2.7 1 1 0 1 1 1 1 Cytochrome P450 KH_1 PF00013.29 KIK44596.1 - 1.5e-86 284.2 36.8 3.7e-13 49.1 0.4 14.5 14 2 0 14 14 14 9 KH domain KH_2 PF07650.17 KIK44596.1 - 1.6e-08 34.2 20.9 1.4 8.8 0.2 8.1 8 1 0 8 8 8 5 KH domain SLS PF14611.6 KIK44596.1 - 2.8e-07 30.6 18.8 0.067 13.0 0.0 7.6 6 2 2 8 8 8 3 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 KIK44596.1 - 0.00041 20.2 6.2 16 5.4 0.1 6.5 7 0 0 7 7 7 2 KH domain MOEP19 PF16005.5 KIK44596.1 - 0.04 13.9 0.0 0.26 11.3 0.0 2.4 1 0 0 1 1 1 0 KH-like RNA-binding domain DUF4974 PF16344.5 KIK44596.1 - 0.081 12.9 0.1 1.3 9.1 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) KH_5 PF13184.6 KIK44596.1 - 3.3 7.9 15.2 4.1 7.6 0.5 5.9 6 1 1 7 7 7 0 NusA-like KH domain RRM_1 PF00076.22 KIK44597.1 - 1.3e-09 37.7 0.0 3.8e-05 23.4 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 KIK44597.1 - 1.9e-07 31.0 0.2 4.2e-07 29.9 0.2 1.6 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 KIK44597.1 - 0.017 15.9 0.0 0.045 14.6 0.0 1.8 1 0 0 1 1 1 0 RNA polymerase II-binding domain. RRM_7 PF16367.5 KIK44597.1 - 0.074 13.2 0.0 0.28 11.3 0.0 2.0 1 0 0 1 1 1 0 RNA recognition motif Metallophos PF00149.28 KIK44598.1 - 9.8e-28 98.0 0.0 1.4e-27 97.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 KIK44598.1 - 3.2e-12 46.6 0.0 5e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 KIK44599.1 - 5.8e-11 41.7 1.6 2.4e-06 27.1 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK44599.1 - 1.4e-06 27.9 1.2 0.00073 19.5 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIK44599.1 - 6.3e-06 26.2 0.1 0.00014 22.0 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat PPP5 PF08321.12 KIK44599.1 - 3.3e-05 24.1 0.3 7.6e-05 22.9 0.1 1.7 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_8 PF13181.6 KIK44599.1 - 6.7e-05 22.8 0.6 0.0086 16.2 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK44599.1 - 0.00015 21.4 0.6 0.026 14.2 0.1 2.7 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.6 KIK44599.1 - 0.003 18.0 0.2 0.0094 16.4 0.1 1.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIK44599.1 - 0.0076 16.8 0.2 0.023 15.3 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 KIK44599.1 - 0.014 14.6 0.1 0.018 14.3 0.1 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 KIK44599.1 - 0.02 15.0 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Phage_lysis PF03245.13 KIK44599.1 - 0.062 13.4 0.1 0.091 12.9 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein SLT PF01464.20 KIK44600.1 - 7.1e-10 38.6 0.0 1.3e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain Cyclin PF08613.11 KIK44602.1 - 0.0017 18.7 0.0 0.0046 17.3 0.0 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KIK44602.1 - 0.092 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain NTS PF15447.6 KIK44603.1 - 0.079 13.5 0.3 0.18 12.3 0.3 1.6 1 0 0 1 1 1 0 N-terminal segments of PfEMP1 Helicase_C_3 PF13625.6 KIK44603.1 - 0.15 12.2 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Zn_clus PF00172.18 KIK44605.1 - 1.8e-07 31.2 8.2 3e-07 30.5 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M16_M PF16187.5 KIK44606.1 - 0.14 11.4 0.0 0.16 11.2 0.0 1.0 1 0 0 1 1 1 0 Middle or third domain of peptidase_M16 DUF3703 PF12487.8 KIK44609.1 - 0.082 12.7 0.0 0.18 11.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3703) Pkinase PF00069.25 KIK44610.1 - 3.4e-61 206.9 0.0 4.4e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK44610.1 - 1.5e-33 116.2 0.0 2e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK44610.1 - 0.00035 19.5 0.0 0.00046 19.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RHS PF03527.14 KIK44610.1 - 0.024 14.4 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 RHS protein Kinase-like PF14531.6 KIK44610.1 - 0.027 13.8 0.0 0.062 12.6 0.0 1.5 1 0 0 1 1 1 0 Kinase-like PSI PF01437.25 KIK44611.1 - 0.066 13.8 0.2 0.16 12.5 0.2 1.6 1 0 0 1 1 1 0 Plexin repeat Acetyltransf_1 PF00583.25 KIK44612.1 - 5.6e-13 49.1 0.0 7.2e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK44612.1 - 1.6e-08 34.9 0.0 2.3e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIK44612.1 - 2.1e-07 30.9 0.0 2.7e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIK44612.1 - 5.5e-05 23.4 0.0 7.6e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIK44612.1 - 0.00033 20.3 0.0 0.00051 19.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK44612.1 - 0.0013 18.6 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KIK44612.1 - 0.0088 16.7 0.0 0.011 16.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain dNK PF01712.19 KIK44612.1 - 0.033 14.1 0.1 0.052 13.4 0.1 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase zf-C2H2 PF00096.26 KIK44613.1 - 1.7e-10 40.7 9.4 1.5e-05 25.2 0.5 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK44613.1 - 2e-06 28.2 7.7 0.014 16.2 0.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK44613.1 - 3.3e-06 27.3 8.2 1.5e-05 25.1 0.4 3.6 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KIK44613.1 - 0.0011 19.1 1.4 0.046 14.0 0.3 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIK44613.1 - 0.0053 17.1 0.4 2.8 8.4 0.3 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 KIK44613.1 - 0.019 15.6 0.6 0.16 12.7 0.1 2.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats BolA PF01722.18 KIK44613.1 - 0.032 14.5 0.0 9.6 6.6 0.0 2.2 2 0 0 2 2 2 0 BolA-like protein zf-C2H2_6 PF13912.6 KIK44613.1 - 0.037 14.1 3.3 0.82 9.7 0.9 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KIK44613.1 - 0.045 13.5 3.1 2.4 8.0 0.2 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type DNA_ligase_A_M PF01068.21 KIK44615.1 - 2.1e-41 141.8 0.0 3.6e-40 137.8 0.0 2.2 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KIK44615.1 - 6.8e-31 107.9 0.0 1.4e-30 106.9 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KIK44615.1 - 1.7e-16 60.6 0.0 4.5e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BolA PF01722.18 KIK44619.1 - 3.1e-29 101.1 0.7 3.7e-29 100.8 0.7 1.1 1 0 0 1 1 1 1 BolA-like protein zf-C2H2 PF00096.26 KIK44620.1 - 1.5e-13 50.4 5.3 8.4e-07 29.1 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK44620.1 - 4.2e-09 36.5 3.9 0.0002 21.9 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK44620.1 - 7.8e-07 29.3 12.5 0.00018 21.8 0.3 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KIK44620.1 - 0.0001 22.5 0.4 0.00027 21.1 0.4 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIK44620.1 - 0.00076 19.8 0.3 0.0027 18.1 0.3 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KIK44620.1 - 0.0011 18.9 1.9 0.015 15.3 0.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KIK44620.1 - 0.0016 18.3 2.8 0.06 13.3 0.1 2.4 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-BED PF02892.15 KIK44620.1 - 0.071 13.1 1.9 0.21 11.6 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_3rep PF18868.1 KIK44620.1 - 0.084 13.6 0.7 9.3 6.9 0.1 2.4 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats DUF3268 PF11672.8 KIK44620.1 - 0.086 13.2 0.2 0.13 12.6 0.2 1.3 1 0 0 1 1 1 0 zinc-finger-containing domain Zn-ribbon_8 PF09723.10 KIK44620.1 - 0.33 11.1 2.7 20 5.4 1.4 2.6 1 1 1 2 2 2 0 Zinc ribbon domain Pkinase PF00069.25 KIK44621.1 - 2.6e-54 184.4 0.0 7.7e-37 127.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK44621.1 - 7.1e-22 77.9 0.0 1.4e-15 57.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIK44621.1 - 0.00023 20.6 0.5 0.0097 15.2 0.0 2.9 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 KIK44621.1 - 0.0011 19.0 1.0 0.0025 17.8 0.2 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK44621.1 - 0.046 12.7 0.1 0.066 12.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KIK44621.1 - 0.08 12.6 0.0 4 7.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KIK44621.1 - 0.17 10.7 0.0 0.3 9.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Homeodomain PF00046.29 KIK44622.1 - 1.9e-16 59.7 3.9 4.7e-16 58.4 3.9 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KIK44622.1 - 0.00022 21.1 0.1 0.00022 21.1 0.1 2.9 3 0 0 3 3 3 1 Homeobox KN domain YdaS_antitoxin PF15943.5 KIK44622.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT ABC_tran PF00005.27 KIK44624.1 - 2.2e-46 157.8 0.7 5.4e-27 95.0 0.0 3.5 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIK44624.1 - 1.2e-13 51.5 0.0 0.0094 15.8 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIK44624.1 - 6.8e-12 45.3 0.0 0.00093 18.7 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.24 KIK44624.1 - 7.1e-11 41.9 0.1 1.5e-10 40.8 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 KIK44624.1 - 2.7e-07 31.3 0.0 0.0043 17.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KIK44624.1 - 2.9e-06 26.9 1.1 0.072 12.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 KIK44624.1 - 6.8e-06 26.4 0.0 0.13 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KIK44624.1 - 8e-06 26.4 0.0 0.12 13.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KIK44624.1 - 9e-06 26.2 0.6 0.45 10.9 0.0 3.8 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KIK44624.1 - 2.4e-05 24.6 0.1 0.67 10.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 KIK44624.1 - 2.4e-05 24.5 0.0 0.39 10.8 0.0 2.9 3 0 0 3 3 2 2 Helicase HerA, central domain MMR_HSR1 PF01926.23 KIK44624.1 - 3e-05 24.1 0.0 0.087 12.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK44624.1 - 0.00031 20.7 0.1 0.35 10.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 KIK44624.1 - 0.00052 20.2 0.0 0.23 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KIK44624.1 - 0.00054 19.9 0.0 0.094 12.6 0.0 2.8 3 0 0 3 3 2 1 NACHT domain MeaB PF03308.16 KIK44624.1 - 0.00089 18.3 0.5 0.46 9.4 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB IFRD PF05004.13 KIK44624.1 - 0.0013 17.9 0.5 0.0053 15.9 0.3 2.0 2 1 0 2 2 2 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 KIK44624.1 - 0.0014 19.1 9.3 0.33 11.5 0.3 4.9 5 0 0 5 5 4 1 HEAT-like repeat AAA_24 PF13479.6 KIK44624.1 - 0.0017 18.1 0.0 2.1 8.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain HEAT PF02985.22 KIK44624.1 - 0.0018 18.3 4.8 1 9.8 0.2 4.3 4 0 0 4 4 3 1 HEAT repeat AAA_30 PF13604.6 KIK44624.1 - 0.0035 17.1 0.0 2.5 7.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KIK44624.1 - 0.005 17.2 0.0 2.9 8.3 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_13 PF13166.6 KIK44624.1 - 0.01 14.5 0.0 0.99 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KIK44624.1 - 0.019 15.2 0.0 7.3 6.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KIK44624.1 - 0.02 14.7 0.1 6.9 6.4 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 KIK44624.1 - 0.023 14.7 0.1 10 6.2 0.0 3.0 2 1 0 2 2 2 0 AAA domain MMS19_C PF12460.8 KIK44624.1 - 0.034 13.3 1.0 0.095 11.8 0.6 1.9 1 1 1 2 2 2 0 RNAPII transcription regulator C-terminal AAA_5 PF07728.14 KIK44624.1 - 0.038 14.0 0.2 5.5 7.0 0.0 3.5 5 0 0 5 5 2 0 AAA domain (dynein-related subfamily) UME PF08064.13 KIK44624.1 - 0.038 13.9 0.1 0.24 11.3 0.1 2.3 2 0 0 2 2 2 0 UME (NUC010) domain Ploopntkinase3 PF18751.1 KIK44624.1 - 0.046 13.6 0.0 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 CLASP_N PF12348.8 KIK44624.1 - 0.052 13.1 0.1 4.8 6.7 0.2 2.5 2 0 0 2 2 2 0 CLASP N terminal AAA_7 PF12775.7 KIK44624.1 - 0.053 13.0 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_15 PF13175.6 KIK44624.1 - 0.055 13.2 1.4 2.5 7.7 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 KIK44624.1 - 0.089 12.0 0.1 9.3 5.4 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain AAA_27 PF13514.6 KIK44624.1 - 0.096 12.3 0.0 6.9 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KIK44624.1 - 0.098 12.2 0.2 19 4.8 0.1 2.8 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 KIK44624.1 - 0.099 11.8 0.0 0.38 9.9 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit ATPase_2 PF01637.18 KIK44624.1 - 0.11 12.3 0.1 35 4.2 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Tudor-knot PF11717.8 KIK44624.1 - 0.13 12.2 0.2 0.28 11.1 0.2 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Arf PF00025.21 KIK44624.1 - 0.13 11.7 0.0 3.2 7.2 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family UNC45-central PF11701.8 KIK44624.1 - 0.17 11.8 1.7 3.2 7.7 0.5 2.9 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central DUF3584 PF12128.8 KIK44624.1 - 0.25 8.8 1.4 4.4 4.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Glyco_hydro_18 PF00704.28 KIK44625.1 - 2.2e-81 274.0 0.2 2.9e-81 273.6 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GTP_EFTU PF00009.27 KIK44627.1 - 2.6e-17 63.0 0.0 6.3e-17 61.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KIK44627.1 - 2.2e-07 31.2 1.3 1.7e-06 28.3 0.2 3.1 4 0 0 4 4 4 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KIK44627.1 - 2.4e-05 24.6 0.1 6.4e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain zf-H2C2_5 PF13909.6 KIK44628.1 - 2.6e-10 39.9 17.7 2.6e-05 23.9 1.5 3.5 3 1 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIK44628.1 - 4.7e-07 29.9 15.2 0.009 16.4 0.5 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK44628.1 - 6.3e-05 23.5 14.2 0.02 15.7 1.0 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK44628.1 - 0.00034 20.9 0.2 0.00034 20.9 0.2 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 KIK44628.1 - 0.23 11.1 5.2 0.59 9.8 0.3 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain OrsD PF12013.8 KIK44628.1 - 0.33 11.4 9.1 4.2 7.8 0.1 2.9 1 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D FOXP-CC PF16159.5 KIK44628.1 - 0.69 10.6 7.8 12 6.6 0.6 2.9 1 1 2 3 3 3 0 FOXP coiled-coil domain Form_Nir_trans PF01226.17 KIK44631.1 - 1.6e-75 253.5 18.6 1.9e-75 253.2 18.6 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter DUF3128 PF11326.8 KIK44634.1 - 3.7e-25 88.1 1.5 4.9e-25 87.7 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) MCM PF00493.23 KIK44635.1 - 1.3e-99 331.8 0.0 1.9e-99 331.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KIK44635.1 - 1.5e-37 128.2 0.0 2.9e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KIK44635.1 - 3.4e-29 102.1 23.7 6.9e-29 101.1 21.5 2.5 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 KIK44635.1 - 5.5e-26 90.8 0.7 1.7e-25 89.2 0.7 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KIK44635.1 - 2.6e-13 50.4 0.0 6.8e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KIK44635.1 - 1.6e-07 30.9 0.0 3.9e-06 26.4 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KIK44635.1 - 6.9e-06 26.1 0.0 1.9e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) SelR PF01641.18 KIK44635.1 - 0.0003 20.9 0.2 0.13 12.4 0.1 2.4 2 0 0 2 2 2 2 SelR domain AAA_3 PF07726.11 KIK44635.1 - 0.0013 18.6 0.1 0.027 14.3 0.0 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KIK44635.1 - 0.0038 16.9 0.1 0.028 14.1 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain Yippee-Mis18 PF03226.14 KIK44635.1 - 0.016 15.4 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly CDC27 PF09507.10 KIK44635.1 - 0.58 9.5 4.3 1 8.7 4.3 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CHCH PF06747.13 KIK44636.1 - 3.2e-08 33.5 3.2 6.2e-08 32.6 3.2 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KIK44636.1 - 0.024 15.1 2.6 0.044 14.2 2.6 1.4 1 0 0 1 1 1 0 GCK domain Na_H_Exchanger PF00999.21 KIK44638.1 - 6.2e-60 203.0 21.9 8.3e-60 202.6 21.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MNHE PF01899.16 KIK44638.1 - 1.4 8.7 11.4 0.57 9.9 0.6 3.2 2 1 1 3 3 3 0 Na+/H+ ion antiporter subunit Pkinase PF00069.25 KIK44639.1 - 3e-61 207.1 0.0 3.5e-61 206.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK44639.1 - 1.7e-17 63.5 0.0 2.8e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK44639.1 - 2.3e-08 34.3 1.9 2.4e-05 24.4 0.2 2.5 3 0 0 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK44639.1 - 0.0038 16.1 0.0 0.0055 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KIK44639.1 - 0.023 14.3 0.0 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase L27 PF02828.16 KIK44639.1 - 0.04 13.7 0.0 0.28 11.0 0.0 2.3 3 0 0 3 3 3 0 L27 domain Sec7 PF01369.20 KIK44640.1 - 1.4e-34 119.4 0.0 1.8e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Sec7 domain CxC5 PF18718.1 KIK44641.1 - 2.6e-18 66.2 0.4 2.6e-18 66.2 0.4 1.0 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases Sec63 PF02889.16 KIK44645.1 - 0.079 12.1 0.0 0.092 11.9 0.0 1.1 1 0 0 1 1 1 0 Sec63 Brl domain KDZ PF18758.1 KIK44647.1 - 4.6e-35 121.2 1.1 4.6e-35 121.2 1.1 1.7 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KIK44648.1 - 8.7e-50 169.4 1.1 1.1e-49 169.1 1.1 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF1280 PF06918.14 KIK44649.1 - 0.043 13.4 0.1 0.046 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) DUF659 PF04937.15 KIK44650.1 - 4e-05 23.5 0.1 0.0027 17.6 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 KIK44650.1 - 0.087 12.6 0.0 0.94 9.3 0.0 2.3 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region RVT_1 PF00078.27 KIK44654.1 - 0.0037 16.8 0.0 0.0079 15.7 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_int_SAM_4 PF13495.6 KIK44655.1 - 0.043 14.3 0.0 0.75 10.3 0.0 2.2 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain Phage_integrase PF00589.22 KIK44655.1 - 0.063 13.1 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family Phage_int_SAM_1 PF02899.17 KIK44655.1 - 0.098 13.0 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Paf1 PF03985.13 KIK44658.1 - 1.4e-64 218.7 0.0 1.9e-64 218.3 0.0 1.1 1 0 0 1 1 1 1 Paf1 Peptidase_S10 PF00450.22 KIK44660.1 - 1.8e-64 218.7 2.1 2.3e-46 159.1 2.3 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase Aldedh PF00171.22 KIK44661.1 - 4.6e-15 55.1 6.8 1.3e-12 47.0 4.9 2.5 2 1 0 2 2 2 2 Aldehyde dehydrogenase family SHNi-TPR PF10516.9 KIK44662.1 - 3.2e-16 58.5 0.7 2.2e-12 46.2 0.1 2.6 2 0 0 2 2 2 2 SHNi-TPR TPR_12 PF13424.6 KIK44662.1 - 1e-13 51.3 12.5 1.2e-07 31.9 1.3 3.8 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK44662.1 - 4.3e-09 35.8 1.7 0.007 16.1 0.6 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK44662.1 - 3.7e-06 26.6 12.6 0.067 13.3 2.1 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK44662.1 - 0.00022 21.2 11.4 0.086 13.1 0.6 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK44662.1 - 0.00076 19.1 7.9 0.65 9.7 0.1 4.1 2 2 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 KIK44662.1 - 0.00093 19.8 9.2 0.056 14.1 3.3 3.8 3 2 0 3 3 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KIK44662.1 - 0.013 15.4 8.1 0.06 13.2 0.8 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK44662.1 - 0.014 15.9 7.0 0.13 12.8 0.1 3.7 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK44662.1 - 0.074 13.1 7.5 1 9.5 0.4 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KIK44662.1 - 0.1 11.9 3.6 1.5 8.1 0.3 2.2 2 0 0 2 2 2 0 MalT-like TPR region CreD PF06123.12 KIK44662.1 - 0.16 10.7 0.1 2.3 6.9 0.0 2.0 2 0 0 2 2 2 0 Inner membrane protein CreD TPR_3 PF07720.12 KIK44662.1 - 0.17 12.0 3.8 0.54 10.3 1.7 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK44662.1 - 0.17 12.8 9.5 18 6.5 0.2 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat ANTH PF07651.16 KIK44663.1 - 1.1e-50 172.1 0.2 1.6e-50 171.7 0.2 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KIK44663.1 - 0.0012 18.9 0.0 0.0026 17.8 0.0 1.6 1 0 0 1 1 1 1 ENTH domain Glyco_hydro_47 PF01532.20 KIK44664.1 - 5.3e-132 441.0 0.0 6.3e-132 440.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 FGGY_C PF02782.16 KIK44665.1 - 2.6e-62 210.1 1.2 7.5e-62 208.6 0.9 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KIK44665.1 - 8.1e-61 205.7 0.1 2.6e-59 200.8 0.1 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DEAD PF00270.29 KIK44666.1 - 2.9e-40 137.9 0.4 4.3e-40 137.3 0.4 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK44666.1 - 9e-28 96.8 0.0 4.3e-27 94.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK44666.1 - 0.00045 20.3 0.0 0.00098 19.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Trypan_PARP PF05887.11 KIK44666.1 - 0.99 9.4 4.4 2 8.4 4.4 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4471 PF14740.6 KIK44667.1 - 0.017 14.4 1.6 0.024 13.9 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) FANC_SAP PF18081.1 KIK44667.1 - 0.17 12.1 2.3 0.41 10.8 0.1 2.5 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain Zip PF02535.22 KIK44668.1 - 2.1e-56 191.6 13.7 2.8e-56 191.1 13.7 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Peptidase_M28 PF04389.17 KIK44669.1 - 2.6e-27 95.8 0.0 3.9e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIK44669.1 - 3.9e-07 30.0 0.0 1.1e-06 28.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 CRAL_TRIO PF00650.20 KIK44671.1 - 5.7e-26 91.1 0.0 8.5e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK44671.1 - 8.3e-06 25.9 0.0 2.8e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KIK44671.1 - 0.098 12.8 0.0 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain TPT PF03151.16 KIK44672.1 - 8.9e-58 195.9 15.1 1e-57 195.8 15.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KIK44672.1 - 7.7e-15 55.3 23.5 1.4e-07 31.8 9.8 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KIK44672.1 - 2e-08 33.8 15.7 2.5e-08 33.5 15.7 1.1 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KIK44672.1 - 0.031 13.5 3.9 0.54 9.4 0.1 2.6 2 1 0 2 2 2 0 Nucleotide-sugar transporter DUF4536 PF15055.6 KIK44672.1 - 0.085 13.1 0.0 0.79 10.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) DUF5317 PF17248.2 KIK44672.1 - 5.4 7.0 12.6 5.3 7.0 0.7 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5317) Abhydrolase_6 PF12697.7 KIK44673.1 - 8.5e-06 26.5 0.2 1.4e-05 25.9 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_S4e PF00900.20 KIK44674.1 - 8.9e-37 124.8 0.0 2.6e-36 123.4 0.0 1.8 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KIK44674.1 - 7.3e-26 89.6 0.1 1.2e-25 88.8 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KIK44674.1 - 3.8e-21 74.9 5.8 8e-21 73.9 5.8 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KIK44674.1 - 7.6e-06 25.5 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KIK44674.1 - 4.2e-05 23.3 3.0 0.00013 21.8 3.0 1.9 1 0 0 1 1 1 1 KOW motif Sipho_tail PF05709.11 KIK44674.1 - 0.075 12.4 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Phage tail protein DRMBL PF07522.14 KIK44675.1 - 2.3e-29 101.8 0.0 3.9e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KIK44675.1 - 3.5e-07 29.9 0.0 7e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIK44675.1 - 0.03 14.3 2.8 0.12 12.3 2.8 2.0 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Aminotran_3 PF00202.21 KIK44676.1 - 1.3e-72 244.7 0.0 1.6e-72 244.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III HECT PF00632.25 KIK44677.1 - 2.4e-75 253.9 0.0 3.5e-75 253.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 KIK44677.1 - 0.22 11.6 0.6 5.6 7.1 0.0 3.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat UIM PF02809.20 KIK44677.1 - 0.61 10.1 3.8 3.2 7.9 3.8 2.4 1 0 0 1 1 1 0 Ubiquitin interaction motif Imm5 PF14423.6 KIK44677.1 - 2.6 8.3 6.3 0.2 11.9 0.1 2.4 3 0 0 3 3 3 0 Immunity protein Imm5 ZZ PF00569.17 KIK44678.1 - 2e-19 69.1 59.7 1.4e-06 28.0 13.1 6.3 6 0 0 6 6 6 4 Zinc finger, ZZ type PB1 PF00564.24 KIK44678.1 - 6.2e-08 32.5 0.0 1.4e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 PB1 domain C1_2 PF03107.16 KIK44678.1 - 0.34 11.3 63.4 0.052 13.9 3.0 6.5 7 0 0 7 7 7 0 C1 domain PHF5 PF03660.14 KIK44679.1 - 1.9e-52 175.9 7.9 2.1e-52 175.7 7.9 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KIK44679.1 - 0.038 11.9 4.9 0.042 11.7 4.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 KIK44679.1 - 0.42 10.7 15.0 1.6 8.8 1.8 2.9 1 1 1 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 KIK44679.1 - 2 8.8 17.7 0.37 11.1 2.7 2.6 1 1 1 2 2 2 0 C1 domain Ribosomal_L29e PF01779.17 KIK44680.1 - 1.1e-18 67.3 8.9 1.1e-18 67.3 8.9 1.5 2 0 0 2 2 2 1 Ribosomal L29e protein family DSPc PF00782.20 KIK44681.1 - 4.8e-29 100.8 0.0 6.8e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIK44681.1 - 0.001 18.7 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KIK44681.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.13 KIK44681.1 - 0.041 13.4 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Med4 PF10018.9 KIK44682.1 - 4.4e-18 65.7 0.0 7.6e-18 64.9 0.0 1.4 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Tmemb_14 PF03647.13 KIK44683.1 - 2.5e-19 69.8 6.1 3.1e-19 69.5 6.1 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C PilS PF08805.11 KIK44685.1 - 0.035 13.9 2.0 0.14 12.0 0.6 2.3 2 0 0 2 2 2 0 PilS N terminal FlgN PF05130.12 KIK44686.1 - 0.016 15.7 1.1 3.5 8.1 0.2 2.8 3 0 0 3 3 3 0 FlgN protein IF4E PF01652.18 KIK44687.1 - 1.9e-53 180.5 0.0 2.4e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Methyltransf_31 PF13847.6 KIK44688.1 - 1.3e-10 41.2 0.0 1.7e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK44688.1 - 6.3e-10 39.6 0.0 1.6e-09 38.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK44688.1 - 6.5e-10 39.5 0.0 1.6e-09 38.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK44688.1 - 3.7e-05 24.4 0.0 6.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK44688.1 - 0.00063 19.6 0.0 0.0023 17.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Sec3-PIP2_bind PF15277.6 KIK44688.1 - 0.034 14.3 0.0 0.062 13.4 0.0 1.4 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH BTB PF00651.31 KIK44689.1 - 0.0011 19.2 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Methyltransf_28 PF02636.17 KIK44690.1 - 2.3e-35 122.5 0.0 3.4e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 KIK44690.1 - 0.00079 20.1 0.0 0.0018 19.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 KIK44690.1 - 0.0047 16.0 0.0 0.0077 15.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 KIK44690.1 - 0.046 13.3 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 KIK44690.1 - 0.047 13.5 0.0 0.077 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KIK44690.1 - 0.09 13.5 0.0 0.18 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MMS19_C PF12460.8 KIK44691.1 - 1e-104 351.0 7.4 1e-104 351.0 7.4 2.7 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 KIK44691.1 - 7.4e-94 314.2 0.4 3.3e-91 305.5 0.0 4.0 3 1 1 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.6 KIK44691.1 - 1.8e-09 37.8 4.3 0.0012 19.2 0.1 6.3 5 2 1 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 KIK44691.1 - 1.3e-05 25.6 7.2 0.055 14.0 0.1 7.1 7 1 1 8 8 8 1 HEAT-like repeat Cnd1 PF12717.7 KIK44691.1 - 0.057 13.5 0.0 0.97 9.5 0.1 3.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 KIK44691.1 - 0.11 12.4 0.5 16 5.4 0.0 4.3 4 2 0 4 4 4 0 Domain of unknown function (DUF3385) IGR PF09597.10 KIK44691.1 - 0.11 12.6 0.0 1.4 9.1 0.0 2.7 3 0 0 3 3 3 0 IGR protein motif Fanconi_A_N PF15865.5 KIK44691.1 - 0.2 11.0 2.2 0.54 9.6 0.4 2.6 2 0 0 2 2 2 0 Fanconi anaemia group A protein N terminus MHC_I_C PF06623.11 KIK44691.1 - 0.26 11.2 2.1 0.62 10.0 2.1 1.6 1 0 0 1 1 1 0 MHC_I C-terminus DUF3730 PF12530.8 KIK44691.1 - 3.5 7.1 7.7 1.6 8.3 1.7 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3730) CAS_CSE1 PF03378.15 KIK44696.1 - 9.7e-112 373.7 0.4 1.7e-111 372.8 0.4 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KIK44696.1 - 3.8e-100 335.3 0.0 7.1e-100 334.4 0.0 1.5 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KIK44696.1 - 1.7e-12 47.1 0.0 1.3e-11 44.2 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KIK44696.1 - 0.0012 18.9 0.6 0.074 13.1 0.1 3.7 3 0 0 3 3 3 1 Exportin 1-like protein DNA_pol_phi PF04931.13 KIK44696.1 - 0.043 11.9 0.3 0.55 8.3 0.1 2.6 3 0 0 3 3 3 0 DNA polymerase phi SMN PF06003.12 KIK44696.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) HEAT PF02985.22 KIK44696.1 - 2.3 8.7 3.8 89 3.8 0.1 4.2 4 0 0 4 4 4 0 HEAT repeat ABC2_membrane PF01061.24 KIK44699.1 - 9.9e-76 253.8 63.4 7.5e-43 146.4 21.9 3.5 5 0 0 5 5 5 2 ABC-2 type transporter ABC_tran PF00005.27 KIK44699.1 - 4.3e-38 130.9 0.0 2.8e-18 66.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KIK44699.1 - 3.1e-32 110.3 12.4 2.2e-27 94.8 0.2 3.7 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KIK44699.1 - 1.1e-14 54.8 0.0 2.2e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KIK44699.1 - 5.3e-06 26.9 0.0 0.0019 18.6 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIK44699.1 - 5.7e-06 26.3 0.1 8.4e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 KIK44699.1 - 1.5e-05 24.3 47.2 0.0023 17.1 21.7 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_18 PF13238.6 KIK44699.1 - 5.9e-05 23.6 0.0 0.025 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIK44699.1 - 7e-05 23.1 0.0 0.03 14.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIK44699.1 - 7.4e-05 22.4 0.0 0.01 15.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIK44699.1 - 0.00092 18.9 0.4 0.22 11.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.12 KIK44699.1 - 0.0014 18.6 0.1 0.21 11.5 0.0 2.9 3 0 0 3 3 3 1 NACHT domain MMR_HSR1 PF01926.23 KIK44699.1 - 0.0017 18.4 0.1 0.74 9.9 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KIK44699.1 - 0.0022 17.9 0.3 0.81 9.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system dNK PF01712.19 KIK44699.1 - 0.0067 16.3 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_33 PF13671.6 KIK44699.1 - 0.0097 16.1 0.0 0.49 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIK44699.1 - 0.021 14.5 0.1 1.4 8.6 0.2 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KIK44699.1 - 0.026 14.5 0.0 9.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_17 PF13207.6 KIK44699.1 - 0.048 14.1 0.0 1.3 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KIK44699.1 - 0.086 12.3 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain TsaE PF02367.17 KIK44699.1 - 0.089 12.8 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KIK44699.1 - 0.11 12.9 0.0 6.8 7.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 KIK44699.1 - 0.13 12.3 0.0 21 5.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 KIK44699.1 - 0.15 11.8 0.1 5.6 6.7 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.18 KIK44699.1 - 0.16 11.3 0.2 3 7.1 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 KIK44699.1 - 0.17 12.3 0.0 0.33 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KIK44699.1 - 0.18 11.4 0.4 1 9.0 0.2 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PDR_assoc PF08370.11 KIK44699.1 - 2.1 8.2 7.0 0.38 10.5 0.3 3.3 2 0 0 2 2 2 0 Plant PDR ABC transporter associated CorA PF01544.18 KIK44700.1 - 9.2e-12 44.9 5.5 6.3e-11 42.1 5.5 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Brr6_like_C_C PF10104.9 KIK44700.1 - 0.042 13.6 1.3 0.13 12.0 1.3 1.8 1 1 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain ABC_tran_CTD PF16326.5 KIK44700.1 - 0.071 13.4 2.9 0.46 10.8 0.2 2.8 2 1 0 2 2 2 0 ABC transporter C-terminal domain dCache_2 PF08269.11 KIK44700.1 - 0.11 11.7 2.8 0.17 11.1 2.8 1.3 1 0 0 1 1 1 0 Cache domain PCRF PF03462.18 KIK44700.1 - 0.26 11.2 4.2 0.43 10.4 4.2 1.4 1 0 0 1 1 1 0 PCRF domain Jnk-SapK_ap_N PF09744.9 KIK44700.1 - 4.1 7.6 12.0 1.8 8.7 5.6 2.2 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 WRKY PF03106.15 KIK44701.1 - 0.035 14.3 2.6 0.049 13.9 2.6 1.2 1 0 0 1 1 1 0 WRKY DNA -binding domain UbiA PF01040.18 KIK44702.1 - 4.7e-47 160.4 17.2 6.1e-47 160.0 17.0 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family Epimerase PF01370.21 KIK44703.1 - 4.3e-10 39.5 0.0 5.3e-08 32.6 0.0 2.7 2 1 1 3 3 3 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIK44703.1 - 1.1e-07 31.9 0.0 3.2e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIK44703.1 - 0.0006 18.9 0.0 0.0067 15.5 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KIK44703.1 - 0.014 14.9 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 KIK44703.1 - 0.023 13.8 0.0 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KIK44703.1 - 0.054 12.9 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ANAPC10 PF03256.16 KIK44703.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) NAD_binding_4 PF07993.12 KIK44703.1 - 0.13 11.4 0.5 0.23 10.6 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein Zip PF02535.22 KIK44705.1 - 0.62 9.2 7.4 0.83 8.8 7.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RIBIOP_C PF04950.12 KIK44706.1 - 1.6e-117 392.1 0.0 2.5e-117 391.5 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KIK44706.1 - 7.1e-13 48.5 0.1 4.4e-12 45.9 0.0 2.5 2 1 0 2 2 2 1 AARP2CN (NUC121) domain FeoA PF04023.14 KIK44706.1 - 0.16 12.3 0.0 0.52 10.6 0.0 1.8 1 0 0 1 1 1 0 FeoA domain VID27_N PF17748.1 KIK44706.1 - 1.3 8.9 7.2 2.4 8.0 7.2 1.4 1 0 0 1 1 1 0 VID27 N-terminal region GMC_oxred_N PF00732.19 KIK44707.1 - 2.2e-61 207.8 0.0 2.8e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIK44707.1 - 9.8e-33 113.7 0.1 1.5e-32 113.1 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIK44707.1 - 9.6e-05 22.5 0.2 0.00026 21.2 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK44707.1 - 0.00074 18.7 0.1 0.0011 18.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KIK44707.1 - 0.002 17.8 0.0 0.0048 16.5 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK44707.1 - 0.004 16.4 0.0 0.0082 15.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK44707.1 - 0.0072 15.4 0.0 0.025 13.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KIK44707.1 - 0.075 12.3 0.1 0.17 11.1 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KIK44707.1 - 0.22 10.8 0.1 0.57 9.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK44707.1 - 0.24 10.1 0.0 0.35 9.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein DUF554 PF04474.12 KIK44708.1 - 0.036 13.5 0.1 0.058 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF554) Chromate_transp PF02417.15 KIK44708.1 - 4.6 7.4 10.4 0.88 9.7 5.1 2.2 2 0 0 2 2 2 0 Chromate transporter Adap_comp_sub PF00928.21 KIK44711.1 - 4.3e-93 311.5 0.1 7e-93 310.8 0.0 1.3 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KIK44711.1 - 2.2e-06 27.7 0.5 3.8e-06 26.9 0.5 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KIK44711.1 - 0.0035 16.8 0.0 0.0066 15.9 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain PQ-loop PF04193.14 KIK44712.1 - 3.6e-14 52.3 10.5 6.1e-09 35.5 2.8 3.0 4 0 0 4 4 4 2 PQ loop repeat Syndecan PF01034.20 KIK44712.1 - 0.045 13.7 0.5 2.2 8.2 0.8 2.7 2 0 0 2 2 2 0 Syndecan domain Fer2 PF00111.27 KIK44713.1 - 4.5e-11 42.5 0.1 6.3e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain 4HBT PF03061.22 KIK44716.1 - 5e-11 42.8 0.0 6.9e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 KIK44716.1 - 5.4e-08 33.4 0.0 7.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KIK44716.1 - 0.00011 21.6 0.1 0.0013 18.1 0.3 2.0 2 0 0 2 2 2 1 Acyl-ACP thioesterase SNF2_N PF00176.23 KIK44717.1 - 2.7e-68 230.3 0.2 4e-68 229.7 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK44717.1 - 1.7e-21 76.6 0.0 4e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK44717.1 - 0.0004 20.4 0.0 0.001 19.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KIK44717.1 - 0.014 14.6 0.2 0.18 11.0 0.0 2.3 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 KIK44717.1 - 0.15 11.2 0.0 0.32 10.2 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DTHCT PF08070.11 KIK44717.1 - 5.4 7.8 19.3 0.098 13.4 3.7 3.6 3 0 0 3 3 3 0 DTHCT (NUC029) region SUZ PF12752.7 KIK44718.1 - 1.1e-14 54.9 1.0 1.1e-14 54.9 1.0 3.1 3 1 0 3 3 3 1 SUZ domain DUF5521 PF17659.1 KIK44718.1 - 0.073 10.9 0.5 0.084 10.7 0.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) eIF3_subunit PF08597.10 KIK44718.1 - 6.6 6.6 9.7 13 5.6 9.7 1.6 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit Carmo_coat_C PF08462.10 KIK44720.1 - 0.17 12.0 0.0 0.25 11.5 0.0 1.2 1 0 0 1 1 1 0 Carmovirus coat protein Aminotran_1_2 PF00155.21 KIK44721.1 - 3.6e-54 184.3 0.0 1.6e-42 146.0 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II Aminotran_5 PF00266.19 KIK44721.1 - 0.007 15.4 0.0 0.062 12.2 0.0 2.0 1 1 1 2 2 2 1 Aminotransferase class-V OKR_DC_1 PF01276.20 KIK44721.1 - 0.0072 15.1 0.0 0.017 13.9 0.0 1.5 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 KIK44721.1 - 0.16 11.2 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Peptidase_M20 PF01546.28 KIK44722.1 - 7.1e-35 120.6 0.0 8.8e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIK44722.1 - 3.5e-12 46.2 0.0 8.5e-12 45.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KIK44722.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 CHAT PF12770.7 KIK44723.1 - 1.6e-33 116.4 0.1 3.2e-33 115.4 0.1 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK44723.1 - 1.6e-09 37.3 9.0 0.0014 18.4 0.0 6.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK44723.1 - 0.00054 20.2 8.2 0.44 10.9 0.1 6.1 4 3 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK44723.1 - 0.0016 19.1 2.3 42 5.3 0.0 6.4 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK44723.1 - 0.0018 18.3 1.9 19 5.7 0.1 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK44723.1 - 0.0041 16.9 5.4 5.2 7.1 0.1 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK44723.1 - 0.0052 16.7 3.2 5.6 7.2 0.1 5.0 4 1 0 4 4 4 1 Tetratricopeptide repeat Apolipoprotein PF01442.18 KIK44723.1 - 0.024 14.5 2.5 0.052 13.4 2.5 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Vta1_C PF18097.1 KIK44723.1 - 0.073 12.8 1.5 15 5.4 1.0 3.3 2 0 0 2 2 2 0 Vta1 C-terminal domain DUF2019 PF09450.10 KIK44723.1 - 0.087 12.8 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) DUF5588 PF17826.1 KIK44723.1 - 0.097 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5588) Aminotran_1_2 PF00155.21 KIK44725.1 - 1.1e-51 176.1 0.0 2.5e-43 148.7 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II OKR_DC_1 PF01276.20 KIK44725.1 - 0.00032 19.6 0.0 0.00061 18.6 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 KIK44725.1 - 0.022 13.7 0.0 0.05 12.6 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class-V Beta_elim_lyase PF01212.21 KIK44725.1 - 0.16 11.2 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase HMGL-like PF00682.19 KIK44726.1 - 1.1e-35 123.4 0.0 1.7e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 HMGL-like TPT PF03151.16 KIK44727.1 - 3.3e-12 46.4 24.8 4e-12 46.1 24.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KIK44727.1 - 0.0025 18.0 43.8 0.01 16.0 20.0 2.8 2 1 0 2 2 2 2 EamA-like transporter family DNA_pol_A_exo1 PF01612.20 KIK44728.1 - 9.7e-17 61.2 0.1 3e-15 56.4 0.1 2.1 1 1 0 1 1 1 1 3'-5' exonuclease MatE PF01554.18 KIK44730.1 - 3.3e-52 176.4 22.6 8.1e-27 93.8 7.1 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KIK44730.1 - 3.8e-06 27.0 7.5 3.8e-06 27.0 7.5 4.0 3 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain 4HBT PF03061.22 KIK44731.1 - 5.1e-08 33.1 0.0 8.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KIK44731.1 - 0.0054 17.0 0.0 0.0059 16.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Proteasome PF00227.26 KIK44733.1 - 2.6e-38 131.4 0.0 3.3e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit F-box-like PF12937.7 KIK44734.1 - 0.031 14.2 0.3 0.031 14.2 0.3 2.1 2 0 0 2 2 2 0 F-box-like Mre11_DNA_bind PF04152.14 KIK44735.1 - 4.3e-48 163.8 0.1 4.3e-48 163.8 0.1 2.3 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KIK44735.1 - 5.3e-14 53.2 0.3 9e-14 52.5 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIK44735.1 - 0.00073 19.8 0.0 0.014 15.6 0.0 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain WD40 PF00400.32 KIK44736.1 - 1.7e-28 98.3 10.0 1.1e-05 26.1 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat WD40_like PF17005.5 KIK44736.1 - 9.4e-07 28.4 0.0 0.01 15.2 0.0 2.2 2 0 0 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 KIK44736.1 - 0.00058 20.1 0.0 0.014 15.7 0.0 3.0 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Kelch_6 PF13964.6 KIK44736.1 - 0.11 12.8 1.6 29 5.1 0.1 3.4 3 0 0 3 3 3 0 Kelch motif Nup160 PF11715.8 KIK44736.1 - 0.79 8.3 2.8 12 4.4 0.1 3.4 4 1 0 4 4 4 0 Nucleoporin Nup120/160 Aminotran_1_2 PF00155.21 KIK44737.1 - 1.2e-38 133.3 0.0 1.5e-38 132.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 KIK44737.1 - 0.01 14.5 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Beta_elim_lyase PF01212.21 KIK44737.1 - 0.048 12.9 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Complex1_LYR PF05347.15 KIK44738.1 - 0.00017 21.5 0.0 0.00066 19.7 0.0 2.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Dus PF01207.17 KIK44739.1 - 1.3e-51 175.5 0.0 2e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 KIK44739.1 - 4.2e-07 29.7 4.4 0.00093 19.0 1.3 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KIK44739.1 - 2.1e-06 27.4 6.6 0.0015 18.3 0.6 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 KIK44739.1 - 0.00013 22.6 1.8 0.018 15.7 0.3 2.4 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KIK44739.1 - 0.0081 16.2 7.2 0.65 10.1 0.8 2.5 2 0 0 2 2 2 2 Zinc finger domain Herpes_U44 PF04533.13 KIK44739.1 - 0.037 13.6 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Herpes virus U44 protein UBM PF14377.6 KIK44740.1 - 0.00096 18.5 0.9 0.021 14.2 0.0 2.9 3 0 0 3 3 3 1 Ubiquitin binding region ArfGap PF01412.18 KIK44740.1 - 0.0057 16.7 0.2 0.009 16.1 0.2 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ArfGap PF01412.18 KIK44741.1 - 4.6e-29 100.9 1.0 5.4e-29 100.6 1.0 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF5572 PF17733.1 KIK44742.1 - 2.1e-18 65.8 0.1 3.3e-18 65.3 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5572) EST1 PF10374.9 KIK44745.1 - 2e-20 73.8 0.0 5.8e-20 72.3 0.0 1.8 2 0 0 2 2 2 1 Telomerase activating protein Est1 EST1_DNA_bind PF10373.9 KIK44745.1 - 2.3e-19 70.0 1.1 6.4e-19 68.5 0.0 1.9 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain TPR_1 PF00515.28 KIK44745.1 - 0.17 11.7 0.5 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK44745.1 - 0.2 11.9 0.9 0.44 10.8 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Aminotran_3 PF00202.21 KIK44746.1 - 2e-114 382.4 0.0 2.5e-114 382.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KIK44746.1 - 3.9e-05 23.0 0.0 6.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Amidohydro_1 PF01979.20 KIK44747.1 - 2.3e-35 122.5 0.0 2.9e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIK44747.1 - 1.2e-15 58.0 0.0 1.2e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KIK44748.1 - 1.6e-31 109.9 0.0 2e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIK44748.1 - 9.6e-17 61.6 0.2 5.9e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family RabGAP-TBC PF00566.18 KIK44749.1 - 5e-54 183.2 0.1 8.5e-54 182.5 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cep57_CLD_2 PF14197.6 KIK44749.1 - 0.00019 21.5 7.1 0.00019 21.5 7.1 2.5 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 LURAP PF14854.6 KIK44749.1 - 0.016 15.1 0.4 0.062 13.3 0.4 2.0 1 0 0 1 1 1 0 Leucine rich adaptor protein CCDC144C PF14915.6 KIK44749.1 - 0.025 13.7 6.1 0.04 13.0 6.1 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DivIC PF04977.15 KIK44749.1 - 0.16 11.7 8.0 1.6 8.6 0.3 2.5 1 1 1 2 2 2 0 Septum formation initiator HALZ PF02183.18 KIK44749.1 - 0.16 12.2 2.2 0.26 11.5 0.1 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Phage_GP20 PF06810.11 KIK44749.1 - 0.19 11.5 1.6 0.39 10.5 1.6 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 APG6_N PF17675.1 KIK44749.1 - 0.21 12.1 9.5 0.19 12.3 6.3 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region HAP1_N PF04849.13 KIK44749.1 - 0.22 10.7 11.2 0.047 12.9 7.4 1.7 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Pyrid_ox_like PF16242.5 KIK44750.1 - 8.2e-27 93.6 0.1 1.2e-26 93.1 0.1 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KIK44750.1 - 1.9e-11 44.0 0.0 4.6e-11 42.8 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Nepo_coat PF03391.15 KIK44750.1 - 0.06 12.8 0.0 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 Nepovirus coat protein, central domain Ribosomal_S7 PF00177.21 KIK44757.1 - 7e-37 126.4 1.7 8.6e-37 126.1 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e CFC PF09443.10 KIK44759.1 - 0.058 13.3 3.7 0.095 12.6 3.7 1.3 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) SNF2_N PF00176.23 KIK44761.1 - 4.8e-63 213.0 0.0 7.1e-63 212.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KIK44761.1 - 1.1e-20 73.3 0.0 2.4e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain zf-PARP PF00645.18 KIK44761.1 - 2.3e-14 54.0 0.0 6.6e-14 52.5 0.0 1.9 2 0 0 2 2 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-C3HC4_2 PF13923.6 KIK44761.1 - 2.7e-09 36.7 6.3 5.3e-09 35.8 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 KIK44761.1 - 3.4e-08 33.8 0.0 1.8e-05 25.0 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KIK44761.1 - 2.1e-07 30.7 5.7 4.2e-07 29.7 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KIK44761.1 - 4.6e-07 30.0 1.3 1.8e-06 28.0 0.0 2.4 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 KIK44761.1 - 7.1e-07 29.0 2.9 1.3e-06 28.2 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK44761.1 - 3.1e-06 27.1 8.1 7.3e-06 25.9 8.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIK44761.1 - 5.9e-06 26.5 5.6 1.2e-05 25.5 5.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KIK44761.1 - 1.2e-05 25.2 2.8 2.3e-05 24.2 2.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KIK44761.1 - 1.2e-05 25.4 7.0 2.4e-05 24.4 7.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DEAD PF00270.29 KIK44761.1 - 3.4e-05 23.7 0.0 7.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-rbx1 PF12678.7 KIK44761.1 - 0.00057 20.1 3.8 0.0025 18.0 3.8 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KIK44761.1 - 0.012 15.5 2.7 0.026 14.4 2.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 SPT6_acidic PF14632.6 KIK44761.1 - 0.049 14.2 2.1 0.22 12.2 2.1 2.2 1 0 0 1 1 1 0 Acidic N-terminal SPT6 zf-RING_6 PF14835.6 KIK44761.1 - 0.074 12.9 2.2 0.17 11.8 2.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein PBP1_TM PF14812.6 KIK44761.1 - 0.18 12.2 4.6 0.12 12.8 2.0 2.0 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM199X PF15814.5 KIK44761.1 - 1.4 7.9 6.1 5.9 5.8 6.3 1.8 2 0 0 2 2 2 0 Protein family FAM199X Nse4_C PF08743.10 KIK44762.1 - 4.3e-33 113.4 0.6 1.7e-32 111.5 0.0 2.1 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KIK44762.1 - 7.2e-15 54.8 2.0 1.7e-14 53.6 2.0 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF1515 PF07439.11 KIK44762.1 - 2.6 8.1 8.1 1.3 9.0 0.1 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1515) Gelsolin PF00626.22 KIK44764.1 - 0.00013 21.7 0.0 0.28 11.1 0.0 3.0 3 0 0 3 3 3 2 Gelsolin repeat Tnp_DNA_bind PF14706.6 KIK44767.1 - 0.1 12.5 0.0 0.36 10.7 0.0 1.9 1 0 0 1 1 1 0 Transposase DNA-binding Mnd1 PF03962.15 KIK44772.1 - 1.6e-30 105.2 0.4 3.9e-30 103.9 0.1 1.8 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 KIK44772.1 - 4.7e-11 42.6 0.0 9.4e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Leucine zipper with capping helix domain FUR PF01475.19 KIK44772.1 - 0.0049 17.0 0.0 0.0074 16.4 0.0 1.4 1 0 0 1 1 1 1 Ferric uptake regulator family Penicillinase_R PF03965.16 KIK44772.1 - 0.011 16.1 0.1 0.11 12.9 0.0 2.2 1 1 1 2 2 2 0 Penicillinase repressor TrmB PF01978.19 KIK44772.1 - 0.087 12.7 0.0 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Pkinase PF00069.25 KIK44776.1 - 4.8e-49 167.1 0.0 1.2e-34 119.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK44776.1 - 1.4e-19 70.4 0.0 7.1e-19 68.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK44776.1 - 4.8e-06 26.1 0.0 8.1e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK44776.1 - 0.00055 19.4 0.1 0.00091 18.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK44776.1 - 0.0061 15.4 0.0 0.0092 14.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK44776.1 - 0.0065 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK44776.1 - 0.059 12.3 0.1 0.11 11.4 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain SLAC1 PF03595.17 KIK44777.1 - 7e-77 258.8 45.6 8.1e-77 258.6 45.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel RseC_MucC PF04246.12 KIK44777.1 - 2.9 7.9 9.2 0.27 11.2 3.7 2.1 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC SLAC1 PF03595.17 KIK44778.1 - 1e-62 212.3 36.4 1.3e-62 212.0 36.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel PI3_PI4_kinase PF00454.27 KIK44779.1 - 2.7e-35 122.4 0.0 4.9e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase RRM_1 PF00076.22 KIK44780.1 - 9.4e-13 47.8 0.9 1.8e-05 24.5 0.1 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK44780.1 - 0.00034 20.7 0.0 0.00079 19.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif DUF1866 PF08952.11 KIK44780.1 - 0.016 15.1 0.1 0.26 11.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) Efg1 PF10153.9 KIK44780.1 - 0.079 13.3 1.2 0.19 12.1 0.2 2.1 2 0 0 2 2 2 0 rRNA-processing protein Efg1 Nup35_RRM_2 PF14605.6 KIK44780.1 - 0.09 12.8 0.0 7 6.7 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif ADH_zinc_N PF00107.26 KIK44781.1 - 3.7e-15 56.0 0.0 6.5e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK44781.1 - 1.2e-09 38.0 0.0 2.2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIK44781.1 - 0.00096 20.2 0.0 0.0017 19.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CI-B14_5a PF07347.12 KIK44782.1 - 0.081 12.8 0.3 0.14 12.0 0.3 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) G_glu_transpept PF01019.21 KIK44785.1 - 1.6e-156 522.1 0.0 1.9e-156 521.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Peptidase_A22B PF04258.13 KIK44786.1 - 7.7e-74 248.7 1.0 1e-73 248.4 1.0 1.0 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 KIK44786.1 - 1.7e-07 31.0 6.8 5e-07 29.5 6.8 1.7 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease VIT1 PF01988.19 KIK44786.1 - 0.032 14.1 0.2 0.29 11.0 0.1 2.1 2 0 0 2 2 2 0 VIT family Presenilin PF01080.17 KIK44786.1 - 0.58 8.9 8.2 0.022 13.6 2.0 1.8 2 0 0 2 2 2 0 Presenilin GATA PF00320.27 KIK44787.1 - 2.4e-18 65.4 2.0 4.9e-18 64.4 2.0 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 KIK44787.1 - 2.4e-10 40.0 0.5 6.3e-10 38.7 0.5 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Chorion_2 PF03964.15 KIK44787.1 - 0.14 13.0 10.4 1.6 9.6 1.4 4.1 3 0 0 3 3 3 0 Chorion family 2 Sec7 PF01369.20 KIK44788.1 - 2.7e-29 102.2 0.0 5.6e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KIK44788.1 - 8.6e-28 97.1 0.0 1.7e-27 96.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KIK44788.1 - 0.0016 18.9 0.0 0.0067 16.9 0.0 2.1 1 0 0 1 1 1 1 PH domain Glyco_hydro_76 PF03663.14 KIK44789.1 - 5.9e-39 134.6 21.0 7.2e-39 134.3 21.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Pam16 PF03656.13 KIK44790.1 - 5.1e-20 71.8 0.1 1e-12 48.1 0.0 2.2 2 0 0 2 2 2 2 Pam16 RPA43_OB PF17875.1 KIK44791.1 - 1.4e-28 100.0 0.0 5.2e-28 98.2 0.0 1.8 2 0 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KIK44791.1 - 9e-10 38.8 0.0 2.7e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Aldo_ket_red PF00248.21 KIK44793.1 - 4.1e-70 236.3 0.1 5.2e-70 236.0 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NAF PF03822.14 KIK44793.1 - 0.04 14.1 0.0 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 NAF domain CPSF73-100_C PF11718.8 KIK44794.1 - 7.4e-66 221.8 0.2 1.2e-65 221.1 0.2 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KIK44794.1 - 5e-30 104.0 0.0 1.3e-29 102.7 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 KIK44794.1 - 2.1e-18 67.0 0.2 2.1e-18 67.0 0.2 2.3 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KIK44794.1 - 7.4e-18 64.7 0.0 2e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KIK44794.1 - 6.6e-17 61.2 0.1 1.5e-16 60.0 0.1 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_3 PF13483.6 KIK44794.1 - 7.3e-07 29.2 2.3 6.6e-06 26.1 0.0 3.2 3 1 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KIK44794.1 - 9e-07 28.6 0.1 9e-07 28.6 0.1 2.3 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Arginase PF00491.21 KIK44799.1 - 1.9e-25 89.9 0.2 2.1e-25 89.8 0.2 1.1 1 0 0 1 1 1 1 Arginase family Aminotran_1_2 PF00155.21 KIK44800.1 - 1.3e-29 103.5 0.0 1.6e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CwfJ_C_1 PF04677.15 KIK44801.1 - 1.1e-29 102.8 0.0 2e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 zf-CCHC_2 PF13696.6 KIK44801.1 - 5.9e-27 93.1 18.1 3.4e-11 42.7 2.0 3.5 3 0 0 3 3 3 3 Zinc knuckle CwfJ_C_2 PF04676.14 KIK44801.1 - 1.1e-12 48.7 0.0 1.9e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC PF00098.23 KIK44801.1 - 1.3e-09 37.7 9.9 0.00036 20.5 0.1 3.7 3 0 0 3 3 3 3 Zinc knuckle Zn_ribbon_SprT PF17283.2 KIK44801.1 - 2.2 8.3 7.3 25 4.9 0.0 3.1 2 1 1 3 3 3 0 SprT-like zinc ribbon domain COesterase PF00135.28 KIK44803.1 - 3.3e-59 201.1 0.0 4.2e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK44803.1 - 2.7e-13 50.3 0.1 4.9e-13 49.4 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold NUDIX PF00293.28 KIK44804.1 - 5.3e-10 39.4 0.0 1.9e-09 37.7 0.0 2.0 1 1 0 1 1 1 1 NUDIX domain NIF PF03031.18 KIK44805.1 - 1.1e-23 83.7 0.0 1.6e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 KIK44805.1 - 0.00061 19.5 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family CSN8_PSD8_EIF3K PF10075.9 KIK44807.1 - 8e-14 51.8 0.4 3.7e-12 46.4 0.2 2.8 2 1 0 2 2 2 1 CSN8/PSMD8/EIF3K family DUF1681 PF07933.14 KIK44808.1 - 3.7e-53 179.2 0.0 4.3e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) IN_DBD_C PF00552.21 KIK44808.1 - 0.14 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Integrase DNA binding domain Aminotran_5 PF00266.19 KIK44810.1 - 2e-92 310.0 0.0 2.4e-92 309.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KIK44810.1 - 7.4e-05 22.2 0.8 0.00018 21.0 0.6 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KIK44810.1 - 0.0011 17.6 0.1 0.0018 16.9 0.1 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme RRM_1 PF00076.22 KIK44811.1 - 6.8e-29 99.5 0.0 7.8e-16 57.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KIK44811.1 - 5.3e-05 23.1 0.0 0.0015 18.5 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KIK44811.1 - 0.00099 19.1 0.0 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.6 KIK44811.1 - 0.0055 16.3 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KIK44811.1 - 0.012 15.7 0.0 0.85 9.7 0.0 2.4 2 0 0 2 2 2 0 Limkain b1 DbpA PF03880.15 KIK44811.1 - 0.023 14.7 0.0 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain CAP_GLY PF01302.25 KIK44813.1 - 2.3e-20 72.3 0.1 4.7e-20 71.4 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 KIK44813.1 - 2.1e-14 53.4 8.1 0.00036 20.8 0.0 5.7 4 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KIK44813.1 - 7.7e-12 45.1 0.8 7.3e-10 38.6 0.0 2.8 1 1 2 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 KIK44813.1 - 8.1e-08 31.9 16.6 0.003 17.3 3.0 5.9 2 2 4 6 6 6 4 Leucine rich repeat LRR_6 PF13516.6 KIK44813.1 - 0.00088 19.1 3.4 12 6.3 0.0 5.4 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 KIK44813.1 - 7.3 7.6 9.4 3e+02 2.7 0.0 5.8 6 0 0 6 6 6 0 Leucine Rich Repeat ECH_2 PF16113.5 KIK44814.1 - 1.5e-111 373.2 0.0 1.8e-111 372.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KIK44814.1 - 3e-25 89.0 0.0 1.2e-23 83.8 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase IDO PF01231.18 KIK44815.1 - 1.8e-114 382.9 0.0 2.1e-114 382.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Rep_fac-A_C PF08646.10 KIK44816.1 - 1.5e-50 170.7 1.5 1.1e-49 168.0 0.2 2.2 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KIK44816.1 - 6.5e-38 128.6 0.4 3.2e-37 126.4 0.1 2.3 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 KIK44816.1 - 2.6e-19 69.1 0.3 5.4e-19 68.1 0.3 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KIK44816.1 - 2.5e-13 49.8 0.3 5.9e-12 45.4 0.1 2.6 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF5521 PF17659.1 KIK44816.1 - 0.00017 19.6 0.2 0.011 13.6 0.0 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5521) DUF4539 PF15072.6 KIK44816.1 - 0.014 15.4 0.1 0.062 13.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) DUF223 PF02721.14 KIK44816.1 - 0.051 13.9 0.1 0.19 12.0 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function DUF223 Peroxidase_2 PF01328.17 KIK44818.1 - 2e-45 155.7 0.0 2.6e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Pentapeptide_4 PF13599.6 KIK44820.1 - 0.042 14.0 0.0 0.049 13.8 0.0 1.1 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) Peptidase_M16_M PF16187.5 KIK44821.1 - 7.1e-85 284.7 0.1 2.4e-83 279.7 0.0 2.3 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KIK44821.1 - 1.5e-36 125.6 0.4 8.6e-36 123.2 0.1 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KIK44821.1 - 1.1e-20 74.5 0.0 8.4e-10 39.0 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Sod_Ni PF09055.11 KIK44821.1 - 0.081 13.5 0.1 0.19 12.3 0.1 1.6 1 0 0 1 1 1 0 Nickel-containing superoxide dismutase Apolipoprotein PF01442.18 KIK44821.1 - 0.11 12.4 0.3 16 5.3 0.1 2.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain WD40 PF00400.32 KIK44825.1 - 2e-13 50.5 0.0 2.7e-09 37.5 0.0 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.8 KIK44825.1 - 0.017 13.8 0.0 0.017 13.8 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KIK44825.1 - 0.037 14.3 0.0 0.11 12.8 0.0 1.7 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK44826.1 - 1.4e-17 63.7 5.4 5.5e-07 30.2 0.8 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK44826.1 - 0.0019 18.5 0.0 0.17 12.2 0.0 2.5 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK44826.1 - 0.014 15.3 0.0 7.4 6.6 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF3322 PF11795.8 KIK44826.1 - 0.024 14.6 0.0 0.029 14.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) TPR_2 PF07719.17 KIK44827.1 - 0.00041 20.3 2.2 9.6 6.6 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat NRBF2_MIT PF17169.4 KIK44827.1 - 0.071 13.3 1.9 0.42 10.9 0.2 2.4 2 0 0 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 DUF3856 PF12968.7 KIK44827.1 - 0.082 13.0 0.7 3.9 7.5 0.0 3.0 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) RPN7 PF10602.9 KIK44827.1 - 0.14 11.9 1.8 8.8 6.0 0.2 2.1 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Defensin_big PF14862.6 KIK44828.1 - 0.038 14.3 0.1 0.048 14.0 0.1 1.2 1 0 0 1 1 1 0 Big defensin DUF4166 PF13761.6 KIK44829.1 - 0.013 15.3 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4166) HET PF06985.11 KIK44830.1 - 4.8e-15 56.2 3.3 4e-12 46.7 0.4 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.6 KIK44831.1 - 0.0031 17.9 0.0 0.0035 17.7 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KIK44831.1 - 0.011 16.1 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KIK44831.1 - 0.012 15.6 0.1 0.017 15.0 0.1 1.4 1 1 0 1 1 1 0 NACHT domain APS_kinase PF01583.20 KIK44831.1 - 0.021 14.7 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.6 KIK44831.1 - 0.024 14.8 0.0 0.035 14.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK44831.1 - 0.027 15.0 0.0 0.033 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KIK44831.1 - 0.029 13.6 0.0 0.031 13.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 KIK44831.1 - 0.059 12.5 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 KIK44831.1 - 0.098 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Flavin_Reduct PF01613.18 KIK44832.1 - 1.7e-17 63.9 0.1 2.2e-17 63.5 0.1 1.1 1 0 0 1 1 1 1 Flavin reductase like domain CKS PF01111.19 KIK44833.1 - 4.6e-35 119.7 0.1 5.8e-35 119.4 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Sec63 PF02889.16 KIK44834.1 - 2.3e-26 92.5 0.0 3.4e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KIK44834.1 - 3.8e-21 75.6 0.0 7.3e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIK44834.1 - 6.9e-09 35.9 0.0 1.6e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIK44834.1 - 6.7e-07 29.6 0.0 3.2e-06 27.4 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 KIK44834.1 - 0.00097 19.5 0.1 0.0066 16.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIK44834.1 - 0.0022 17.8 0.0 1.8 8.2 0.0 2.6 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KIK44834.1 - 0.033 14.5 0.3 0.32 11.3 0.3 2.4 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 KIK44834.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Tim54 PF11711.8 KIK44835.1 - 1.9e-57 194.8 0.0 5.1e-57 193.4 0.0 1.5 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 SKIP_SNW PF02731.15 KIK44836.1 - 1.1e-73 246.2 1.6 1.1e-73 246.2 1.6 2.3 2 0 0 2 2 2 1 SKIP/SNW domain SH3_9 PF14604.6 KIK44837.1 - 2.4e-09 36.9 0.0 3.6e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIK44837.1 - 5.8e-08 32.2 0.0 1.7e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KIK44837.1 - 5.3e-07 29.2 0.0 7.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 KIK44837.1 - 0.00051 20.4 0.0 0.00059 20.2 0.0 1.1 1 0 0 1 1 1 1 Helically-extended SH3 domain EF-hand_4 PF12763.7 KIK44838.1 - 0.087 12.8 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Thiamine_BP PF01910.17 KIK44839.1 - 8.1e-27 93.0 0.0 1e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Thiamine-binding protein Ykof PF07615.11 KIK44839.1 - 0.00069 20.0 0.0 0.00093 19.6 0.0 1.2 1 0 0 1 1 1 1 YKOF-related Family APG9 PF04109.16 KIK44840.1 - 1.5e-205 683.7 5.4 1.8e-205 683.5 5.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 HMGL-like PF00682.19 KIK44841.1 - 8.6e-71 238.6 0.0 1.4e-70 237.9 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KIK44841.1 - 4.3e-45 152.9 0.0 2.8e-23 82.3 0.0 2.5 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain tRNA-synt_1c PF00749.21 KIK44842.1 - 7e-107 357.0 0.0 8.9e-107 356.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KIK44842.1 - 7.5e-38 130.1 0.0 1.5e-37 129.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.25 KIK44842.1 - 3e-07 30.6 0.0 7.7e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK44842.1 - 1.1e-05 25.3 0.1 3.1e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK44842.1 - 2.7e-05 24.3 0.0 0.0001 22.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 KIK44842.1 - 0.0013 18.2 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Pkinase PF00069.25 KIK44845.1 - 2e-46 158.5 0.0 3e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK44845.1 - 2.6e-46 158.0 0.0 3.5e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK44845.1 - 0.0092 15.9 0.5 0.083 12.8 0.0 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK44845.1 - 0.013 14.4 0.2 0.035 12.9 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 KIK44845.1 - 0.05 12.6 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pyr_redox_2 PF07992.14 KIK44846.1 - 2.8e-42 144.9 0.0 5.4e-42 144.0 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK44846.1 - 1.2e-11 45.0 0.2 6.3e-08 33.1 0.0 3.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 KIK44846.1 - 1.3e-09 36.9 5.1 4.6e-05 22.7 1.5 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KIK44846.1 - 4e-08 33.6 0.5 0.012 16.0 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KIK44846.1 - 2e-07 30.4 6.3 0.0021 17.8 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KIK44846.1 - 1.6e-06 27.8 3.0 0.024 14.5 1.3 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KIK44846.1 - 7.2e-05 22.1 4.8 0.002 17.6 2.3 2.6 2 0 0 2 2 2 1 EF hand Pyr_redox_3 PF13738.6 KIK44846.1 - 0.00048 19.5 0.2 0.042 13.1 0.5 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KIK44846.1 - 0.0048 17.3 0.0 0.13 12.7 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding XdhC_C PF13478.6 KIK44846.1 - 0.028 14.9 0.0 0.068 13.7 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain EF-hand_4 PF12763.7 KIK44846.1 - 0.21 11.6 4.1 9.2 6.3 0.2 2.5 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand CLP1_P PF16575.5 KIK44847.1 - 1.8e-35 122.4 0.0 3e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KIK44847.1 - 4e-34 116.7 0.0 6.3e-34 116.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 KIK44847.1 - 4.3e-28 98.1 0.0 8.2e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 KIK44847.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 KIK44847.1 - 0.085 13.4 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KIK44847.1 - 0.12 11.9 0.1 0.37 10.3 0.1 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B G-alpha PF00503.20 KIK44847.1 - 0.26 10.4 0.0 0.39 9.8 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit MFS_1 PF07690.16 KIK44848.1 - 6.5e-29 101.0 34.3 2.4e-28 99.1 34.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KIK44848.1 - 3.1e-05 23.5 5.4 3.1e-05 23.5 5.4 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF3098 PF11297.8 KIK44848.1 - 0.046 13.3 5.0 2.1 8.0 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3098) CrgA PF06781.12 KIK44848.1 - 6.1 7.0 8.3 4.7 7.3 0.5 3.4 4 0 0 4 4 4 0 Cell division protein CrgA AAA PF00004.29 KIK44849.1 - 2.9e-14 53.6 0.0 9e-14 52.0 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KIK44849.1 - 6.1e-07 29.5 0.0 3.1e-05 24.0 0.0 2.8 1 1 1 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 KIK44849.1 - 1.9e-05 24.5 0.0 6e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KIK44849.1 - 0.00011 22.6 0.1 0.00095 19.6 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK44849.1 - 0.00013 22.2 0.0 0.0023 18.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KIK44849.1 - 0.00096 19.3 0.0 0.0025 18.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KIK44849.1 - 0.00098 19.2 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KIK44849.1 - 0.0047 16.9 0.0 0.013 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_assoc_2 PF16193.5 KIK44849.1 - 0.0065 16.8 0.0 0.022 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_25 PF13481.6 KIK44849.1 - 0.0065 16.1 0.1 0.22 11.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 KIK44849.1 - 0.017 15.6 0.1 0.1 13.1 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 KIK44849.1 - 0.035 13.8 0.0 0.083 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KIK44849.1 - 0.036 13.4 0.0 0.078 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 KIK44849.1 - 0.038 13.9 0.1 0.35 10.8 0.0 2.3 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 KIK44849.1 - 0.042 13.8 0.0 0.089 12.7 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.6 KIK44849.1 - 0.07 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KIK44849.1 - 0.072 13.5 0.2 0.22 12.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 KIK44849.1 - 0.087 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein CHAT PF12770.7 KIK44850.1 - 0.037 13.4 0.0 0.38 10.1 0.0 1.9 1 1 0 1 1 1 0 CHAT domain TMEM237 PF15383.6 KIK44852.1 - 4.1 6.4 6.7 0.87 8.6 3.2 1.7 1 1 1 2 2 2 0 Transmembrane protein 237 ILVD_EDD PF00920.21 KIK44856.1 - 1.5e-205 683.7 0.0 1.7e-205 683.5 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Eapp_C PF10238.9 KIK44857.1 - 0.046 13.8 0.7 0.13 12.3 0.7 1.7 1 0 0 1 1 1 0 E2F-associated phosphoprotein Imm_superinfect PF14373.6 KIK44858.1 - 0.0037 17.2 0.8 0.0065 16.4 0.8 1.4 1 0 0 1 1 1 1 Superinfection immunity protein Herpes_gE PF02480.16 KIK44858.1 - 0.12 11.1 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CD34_antigen PF06365.12 KIK44858.1 - 0.16 11.5 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family WD40 PF00400.32 KIK44862.1 - 4.4e-09 36.8 0.1 1.3e-08 35.3 0.0 1.7 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.8 KIK44862.1 - 0.044 12.4 0.0 0.044 12.4 0.0 1.0 1 0 0 1 1 1 0 Nucleoporin Nup120/160 GSK-3_bind PF05350.12 KIK44863.1 - 0.11 11.8 0.0 0.12 11.7 0.0 1.0 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding TPR_1 PF00515.28 KIK44864.1 - 1.7e-13 49.7 0.0 0.00023 20.8 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIK44864.1 - 1.5e-12 46.6 6.5 0.00058 19.8 0.0 5.0 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIK44864.1 - 2.9e-08 33.3 0.9 0.12 12.7 0.0 4.7 5 0 0 5 5 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIK44864.1 - 4.9e-08 33.1 10.2 0.021 15.6 0.0 6.7 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIK44864.1 - 6.4e-08 33.1 1.1 0.0001 22.8 0.1 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK44864.1 - 6e-07 29.7 6.1 0.013 15.8 0.1 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIK44864.1 - 1.6e-06 27.7 0.1 2.6 8.3 0.0 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK44864.1 - 0.00021 21.4 0.2 0.37 11.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK44864.1 - 0.0026 17.4 0.0 0.0026 17.4 0.0 4.1 4 1 1 5 5 5 1 TPR repeat TPR_15 PF13429.6 KIK44864.1 - 0.0059 15.9 0.0 0.0059 15.9 0.0 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK44864.1 - 0.0059 17.1 8.8 0.31 11.6 0.0 4.9 3 1 3 6 6 6 3 Tetratricopeptide repeat Coatomer_E PF04733.14 KIK44864.1 - 0.006 16.0 0.0 0.078 12.4 0.0 2.6 2 1 1 3 3 3 1 Coatomer epsilon subunit RPN7 PF10602.9 KIK44864.1 - 0.016 14.9 0.0 0.11 12.2 0.0 2.2 1 1 0 1 1 1 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 KIK44864.1 - 0.021 14.7 6.8 3.3 7.7 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK44864.1 - 0.044 14.0 0.0 0.27 11.5 0.0 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KIK44864.1 - 0.098 13.3 7.0 6.2 7.7 0.0 4.5 5 0 0 5 5 3 0 Tetratricopeptide repeat NTP_transf_5 PF14907.6 KIK44865.1 - 0.14 11.8 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase AAA_12 PF13087.6 KIK44866.1 - 5.9e-33 114.2 0.0 1.1e-32 113.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK44866.1 - 6.5e-30 104.8 3.2 7e-14 52.2 0.0 3.5 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.6 KIK44866.1 - 3.3e-09 36.7 0.0 1.1e-06 28.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KIK44866.1 - 1.4e-08 35.2 0.0 9.3e-07 29.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KIK44866.1 - 0.00068 19.0 0.0 0.028 13.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) FUR PF01475.19 KIK44866.1 - 0.0012 18.9 0.0 0.0031 17.6 0.0 1.6 1 0 0 1 1 1 1 Ferric uptake regulator family zf_CCCH_4 PF18345.1 KIK44866.1 - 0.0068 16.4 4.2 0.0068 16.4 4.2 2.6 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 KIK44866.1 - 0.72 9.7 11.3 0.1 12.5 4.2 3.0 2 0 0 2 2 2 0 CCCH-type zinc finger PAC2 PF09754.9 KIK44872.1 - 4e-25 89.1 0.1 5.5e-25 88.6 0.1 1.1 1 0 0 1 1 1 1 PAC2 family NUC173 PF08161.12 KIK44873.1 - 3.2e-60 203.3 0.5 2.4e-57 193.9 0.1 2.9 3 0 0 3 3 3 2 NUC173 domain HEAT PF02985.22 KIK44873.1 - 0.0067 16.6 0.1 0.98 9.9 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat Kinetochor_Ybp2 PF08568.10 KIK44873.1 - 0.038 12.5 0.0 0.076 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin Dopey_N PF04118.14 KIK44873.1 - 0.098 11.8 0.1 0.57 9.2 0.0 2.2 1 1 0 1 1 1 0 Dopey, N-terminal SAP130_C PF16014.5 KIK44873.1 - 0.19 10.8 1.9 0.52 9.4 1.9 1.7 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Acyltransferase PF01553.21 KIK44874.1 - 3.3e-09 36.5 0.0 3.9e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 Acyltransferase NdhL PF10716.9 KIK44874.1 - 0.077 13.0 10.7 2 8.4 1.6 3.3 1 1 2 3 3 3 0 NADH dehydrogenase transmembrane subunit Trp_oprn_chp PF09534.10 KIK44875.1 - 0.0033 17.2 1.3 0.0054 16.5 1.3 1.3 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Amastin PF07344.11 KIK44875.1 - 0.0058 16.5 0.3 0.013 15.4 0.1 1.5 1 1 1 2 2 2 1 Amastin surface glycoprotein MerC PF03203.14 KIK44875.1 - 0.012 16.1 2.7 0.019 15.4 2.7 1.3 1 0 0 1 1 1 0 MerC mercury resistance protein DUF3040 PF11239.8 KIK44875.1 - 0.015 15.6 4.4 0.66 10.3 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Claudin_2 PF13903.6 KIK44875.1 - 0.033 13.9 0.4 0.043 13.6 0.4 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction LptF_LptG PF03739.14 KIK44875.1 - 0.039 12.8 0.0 0.042 12.7 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF1218 PF06749.12 KIK44875.1 - 0.044 14.3 2.2 0.27 11.8 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) DUF998 PF06197.13 KIK44875.1 - 0.081 12.5 8.3 0.15 11.6 8.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF998) Pox_A14 PF05767.12 KIK44875.1 - 0.11 12.6 1.2 2.2 8.5 0.1 2.1 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 GNAT_acetyltran PF12746.7 KIK44875.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase VirB8 PF04335.13 KIK44875.1 - 0.16 11.8 0.3 0.27 11.1 0.3 1.3 1 0 0 1 1 1 0 VirB8 protein RicinB_lectin_2 PF14200.6 KIK44876.1 - 0.023 15.4 0.1 0.055 14.2 0.1 1.7 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like Inhibitor_I48 PF10467.9 KIK44876.1 - 0.11 12.4 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase inhibitor clitocypin Choline_transpo PF04515.12 KIK44877.1 - 3.2e-82 276.4 17.2 3.2e-82 276.4 17.2 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter TMEMspv1-c74-12 PF11044.8 KIK44877.1 - 0.69 9.9 3.6 2.9 8.0 3.6 2.1 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF3619 PF12279.8 KIK44878.1 - 0.0081 16.5 0.5 0.0081 16.5 0.5 3.1 4 0 0 4 4 4 1 Protein of unknown function (DUF3619) V_ATPase_I PF01496.19 KIK44878.1 - 0.13 10.2 9.8 0.042 11.8 7.1 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Cauli_AT PF03233.13 KIK44878.1 - 0.14 12.1 2.0 0.28 11.1 1.4 1.8 1 1 1 2 2 2 0 Aphid transmission protein GldM_N PF12081.8 KIK44878.1 - 0.15 12.1 5.7 0.21 11.6 5.3 1.4 1 1 0 1 1 1 0 GldM N-terminal domain Mito_fiss_reg PF05308.11 KIK44878.1 - 0.33 11.0 8.5 0.71 9.9 7.1 2.3 1 1 1 2 2 2 0 Mitochondrial fission regulator Med9 PF07544.13 KIK44878.1 - 0.43 10.7 9.4 3.3 7.9 3.8 3.2 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DASH_Spc19 PF08287.11 KIK44878.1 - 8.2 6.3 21.0 4 7.3 2.8 2.3 2 0 0 2 2 2 0 Spc19 WD40 PF00400.32 KIK44880.1 - 0.00032 21.4 3.4 0.016 16.0 0.0 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 KIK44880.1 - 0.00061 19.8 0.0 1.9 8.5 0.0 2.8 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.6 KIK44880.1 - 0.035 14.6 0.2 19 5.9 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain Reg_prop PF07494.11 KIK44880.1 - 0.082 13.2 0.0 18 6.0 0.1 3.6 3 0 0 3 3 3 0 Two component regulator propeller PPR_2 PF13041.6 KIK44881.1 - 1.4e-30 105.2 0.1 1.5e-08 34.7 0.0 7.1 3 2 5 8 8 8 5 PPR repeat family PPR_3 PF13812.6 KIK44881.1 - 1.8e-29 101.6 0.1 1.2e-06 28.5 0.0 5.3 5 0 0 5 5 5 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 KIK44881.1 - 1e-15 57.1 3.1 0.0008 19.1 0.0 6.6 6 0 0 6 6 6 3 PPR repeat PPR_long PF17177.4 KIK44881.1 - 2e-13 50.2 0.0 0.00032 20.1 0.0 4.6 2 2 3 5 5 5 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KIK44881.1 - 5.2e-10 38.9 6.4 0.02 15.1 0.0 6.9 8 0 0 8 8 8 3 PPR repeat PucR PF07905.11 KIK44881.1 - 0.0027 18.0 0.0 0.0051 17.1 0.0 1.4 1 0 0 1 1 1 1 Purine catabolism regulatory protein-like family ECSIT PF06239.11 KIK44881.1 - 0.01 15.0 0.7 0.6 9.2 0.5 3.4 2 1 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway Phage_ABA_S PF18066.1 KIK44881.1 - 0.016 15.8 0.2 11 6.8 0.0 3.4 2 1 1 3 3 3 0 Phage ABA sandwich domain GMP_synt_C PF00958.22 KIK44881.1 - 0.04 14.0 0.0 8.9 6.4 0.0 3.0 3 0 0 3 3 3 0 GMP synthase C terminal domain Rad21_Rec8_N PF04825.13 KIK44882.1 - 2.3e-37 127.5 0.1 3.7e-37 126.9 0.1 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KIK44882.1 - 8.3e-12 44.2 0.0 1.5e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein CHAT PF12770.7 KIK44885.1 - 9.4e-06 25.2 0.0 1.1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 CHAT domain IF-2B PF01008.17 KIK44886.1 - 6.4e-59 199.5 0.0 8.1e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Abhydrolase_3 PF07859.13 KIK44887.1 - 6.9e-30 104.5 0.0 1.2e-21 77.5 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK44887.1 - 0.029 13.2 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase zf-C2H2 PF00096.26 KIK44888.1 - 2.9e-12 46.3 14.5 0.00057 20.2 0.3 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK44888.1 - 9.5e-09 35.4 11.6 0.013 16.3 0.1 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KIK44888.1 - 7.4e-07 29.0 4.9 0.00031 20.6 0.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK44888.1 - 3.9e-05 23.9 0.5 3.9e-05 23.9 0.5 4.6 4 1 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.7 KIK44888.1 - 0.00071 19.9 7.1 0.2 12.1 0.1 4.4 4 0 0 4 4 4 2 Zinc-finger of C2H2 type OSTMP1 PF09777.9 KIK44888.1 - 0.024 14.1 0.5 0.036 13.5 0.5 1.2 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor FOXP-CC PF16159.5 KIK44888.1 - 0.14 12.8 11.0 3.3 8.4 1.1 3.6 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KIK44888.1 - 0.14 12.4 5.0 0.92 9.9 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KIK44888.1 - 0.49 10.7 6.3 3 8.2 3.2 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KIK44888.1 - 0.53 10.6 5.7 0.26 11.6 0.8 2.5 2 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 KIK44888.1 - 7.6 6.7 7.8 3.7 7.7 2.4 2.6 2 0 0 2 2 2 0 BED zinc finger TPR_1 PF00515.28 KIK44889.1 - 1.7e-15 56.1 5.9 0.0017 18.1 0.0 4.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIK44889.1 - 1.9e-15 55.6 5.8 0.0055 16.7 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 KIK44889.1 - 3.1e-13 48.8 0.3 0.25 11.6 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 KIK44889.1 - 2e-11 44.2 8.3 4.8e-06 27.0 0.5 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIK44889.1 - 4.7e-11 42.5 9.5 0.0056 17.4 0.3 5.1 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIK44889.1 - 1.2e-10 40.9 8.2 0.0044 17.3 0.1 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIK44889.1 - 4.6e-10 39.0 3.8 0.0002 21.0 0.6 4.7 2 2 2 4 4 4 2 TPR repeat TPR_12 PF13424.6 KIK44889.1 - 2.1e-08 34.3 7.1 0.00045 20.5 1.4 4.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIK44889.1 - 1.1e-06 29.2 7.5 0.00085 19.9 2.0 3.9 2 2 3 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK44889.1 - 0.00019 21.6 1.4 0.0091 16.2 0.6 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KIK44889.1 - 0.00081 19.5 4.3 0.21 11.8 0.9 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_20 PF14561.6 KIK44889.1 - 0.021 15.1 6.2 13 6.2 0.2 4.2 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIK44889.1 - 0.033 14.8 2.0 1.1e+02 3.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK44889.1 - 0.088 12.9 7.2 6.4 7.1 0.0 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC_CDC26 PF10471.9 KIK44890.1 - 0.011 16.5 0.5 0.015 16.1 0.5 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 PRA1 PF03208.19 KIK44891.1 - 3.4e-30 104.5 3.2 3.9e-30 104.4 3.2 1.1 1 0 0 1 1 1 1 PRA1 family protein Zn_clus PF00172.18 KIK44892.1 - 7.5e-05 22.8 11.6 0.00013 22.0 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 KIK44892.1 - 0.0017 18.4 0.0 0.0034 17.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold Methyltransf_31 PF13847.6 KIK44893.1 - 1.1e-06 28.5 0.0 2.3e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK44893.1 - 2.6e-05 23.8 0.0 0.00055 19.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KIK44893.1 - 5.8e-05 23.7 0.0 0.00014 22.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PrmC_N PF17827.1 KIK44893.1 - 0.00022 21.8 0.1 0.0011 19.5 0.0 2.2 2 0 0 2 2 2 1 PrmC N-terminal domain Methyltransf_23 PF13489.6 KIK44893.1 - 0.0028 17.5 0.0 0.0046 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KIK44893.1 - 0.041 13.5 0.0 1 8.9 0.0 2.6 1 1 1 2 2 2 0 Conserved hypothetical protein 95 PrmA PF06325.13 KIK44893.1 - 0.06 12.7 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) N6_Mtase PF02384.16 KIK44893.1 - 0.2 10.9 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 N-6 DNA Methylase Allantoicase PF03561.15 KIK44894.1 - 1.7e-93 310.2 0.0 3.2e-47 160.1 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_lyase PF04115.12 KIK44894.1 - 1.1e-47 162.3 0.0 1.5e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate lyase GTP_EFTU PF00009.27 KIK44895.1 - 4.3e-58 196.1 0.1 7.1e-58 195.4 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KIK44895.1 - 2.5e-36 124.1 0.1 3.9e-35 120.3 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 KIK44895.1 - 1.1e-30 105.5 0.0 2.2e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KIK44895.1 - 8.5e-23 80.2 0.0 2e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KIK44895.1 - 6.2e-13 48.9 0.1 1.4e-12 47.8 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KIK44895.1 - 5.2e-06 26.3 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SBDS_C PF09377.10 KIK44895.1 - 0.026 14.5 0.0 0.3 11.1 0.0 2.3 2 0 0 2 2 2 0 SBDS protein C-terminal domain BRE1 PF08647.11 KIK44896.1 - 6.3e-22 77.5 8.0 6.3e-22 77.5 8.0 8.7 5 3 2 8 8 8 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 KIK44896.1 - 6.7e-07 29.1 9.5 1.3e-06 28.1 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK44896.1 - 4.9e-06 26.4 12.6 1.1e-05 25.3 12.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KIK44896.1 - 2.8e-05 23.9 11.8 6.3e-05 22.8 11.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK44896.1 - 4.1e-05 23.3 10.9 8.4e-05 22.3 10.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK44896.1 - 0.0003 20.6 8.6 0.00065 19.5 8.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KIK44896.1 - 0.00034 20.9 10.8 0.00076 19.8 10.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KIK44896.1 - 0.0004 20.4 9.3 0.00086 19.3 9.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KIK44896.1 - 0.00086 19.5 7.8 0.0036 17.6 7.8 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain HTH_35 PF13693.6 KIK44896.1 - 0.0043 17.1 0.2 0.25 11.4 0.0 3.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding zf-RING_6 PF14835.6 KIK44896.1 - 0.0071 16.2 3.2 0.013 15.3 3.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zinc_ribbon_9 PF14369.6 KIK44896.1 - 0.069 13.4 3.7 0.16 12.2 3.7 1.6 1 0 0 1 1 1 0 zinc-ribbon NPV_P10 PF05531.12 KIK44896.1 - 0.12 12.9 0.0 0.12 12.9 0.0 5.6 5 2 1 6 6 5 0 Nucleopolyhedrovirus P10 protein zf-RING_4 PF14570.6 KIK44896.1 - 0.26 11.1 8.1 0.66 9.8 7.2 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 KIK44896.1 - 0.3 11.2 5.8 0.95 9.6 5.8 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger DUF1272 PF06906.11 KIK44896.1 - 0.4 10.8 9.7 0.095 12.8 6.0 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF1272) DUF16 PF01519.16 KIK44896.1 - 0.43 11.1 0.1 0.43 11.1 0.1 7.1 2 1 3 5 5 3 0 Protein of unknown function DUF16 Hydantoinase_B PF02538.14 KIK44896.1 - 1.2 7.5 3.7 2.2 6.6 3.7 1.4 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase zf-C3HC4_4 PF15227.6 KIK44896.1 - 1.7 8.9 7.7 3.4 7.9 7.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_5 PF17121.5 KIK44896.1 - 1.7 8.6 5.3 3.7 7.5 5.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KIK44896.1 - 3.2 7.6 6.9 8.3 6.3 6.9 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF4256 PF14066.6 KIK44897.1 - 0.0086 15.8 0.0 0.01 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4256) Gallidermin PF02052.15 KIK44897.1 - 0.039 14.3 0.3 0.06 13.7 0.3 1.5 1 1 0 1 1 1 0 Gallidermin Ribosomal_S9 PF00380.19 KIK44898.1 - 2.2e-43 147.6 0.0 3.8e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ldl_recept_a PF00057.18 KIK44899.1 - 4.6 7.5 11.1 18 5.7 0.3 3.2 2 1 2 4 4 4 0 Low-density lipoprotein receptor domain class A NACHT PF05729.12 KIK44900.1 - 0.0005 20.0 0.0 0.00072 19.5 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK44900.1 - 0.0009 19.7 0.0 0.0012 19.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KIK44900.1 - 0.0057 17.0 0.0 0.0083 16.5 0.0 1.3 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 KIK44900.1 - 0.025 13.8 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 KIK44900.1 - 0.039 13.8 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase Torsin PF06309.11 KIK44900.1 - 0.064 13.4 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 Torsin Parvo_NS1 PF01057.17 KIK44900.1 - 0.07 12.2 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 KIK44900.1 - 0.096 13.2 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KIK44900.1 - 0.15 12.5 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CASP_C PF08172.12 KIK44901.1 - 6.6e-75 251.7 0.0 6.6e-75 251.7 0.0 3.7 2 1 1 4 4 4 1 CASP C terminal KLRAQ PF10205.9 KIK44901.1 - 0.0031 17.7 0.3 0.0031 17.7 0.3 5.1 4 1 2 6 6 6 1 Predicted coiled-coil domain-containing protein Shugoshin_N PF07558.11 KIK44901.1 - 0.0044 16.8 14.2 0.69 9.8 0.1 5.1 5 0 0 5 5 5 2 Shugoshin N-terminal coiled-coil region JIP_LZII PF16471.5 KIK44901.1 - 0.049 13.8 25.0 0.028 14.6 2.1 6.2 5 1 1 6 6 6 0 JNK-interacting protein leucine zipper II HrpB7 PF09486.10 KIK44901.1 - 0.2 12.1 45.2 0.15 12.4 4.7 4.9 3 1 2 5 5 5 0 Bacterial type III secretion protein (HrpB7) SlyX PF04102.12 KIK44901.1 - 0.3 11.7 31.2 3.4 8.3 0.2 7.7 5 1 2 8 8 8 0 SlyX ATG16 PF08614.11 KIK44901.1 - 0.31 11.3 51.2 2.3 8.4 0.7 5.2 3 1 2 5 5 5 0 Autophagy protein 16 (ATG16) SLIDE PF09111.10 KIK44901.1 - 0.49 10.4 6.1 0.093 12.8 1.3 2.4 2 1 0 2 2 2 0 SLIDE NYD-SP28_assoc PF14775.6 KIK44901.1 - 0.54 10.4 12.2 3.4 7.8 0.4 5.2 4 1 1 5 5 5 0 Sperm tail C-terminal domain FlaC_arch PF05377.11 KIK44901.1 - 2.1 8.8 18.7 1.5 9.3 0.2 6.6 6 2 0 6 6 6 0 Flagella accessory protein C (FlaC) PH_TFIIH PF08567.11 KIK44902.1 - 8.8e-19 67.6 0.0 1.6e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.17 KIK44902.1 - 1.4e-18 66.6 0.0 1.3e-12 47.5 0.1 2.7 2 0 0 2 2 2 2 BSD domain TFIID-31kDa PF02291.15 KIK44902.1 - 0.016 15.3 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Put_Phosphatase PF06888.12 KIK44903.1 - 6e-55 186.2 0.0 6.8e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 KIK44903.1 - 5.4e-06 26.9 0.0 1.1e-05 25.9 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 KIK44903.1 - 0.025 14.1 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) HAD_2 PF13419.6 KIK44903.1 - 0.31 11.1 0.7 45 4.1 0.9 2.8 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PET PF06297.14 KIK44904.1 - 0.16 12.3 0.0 0.71 10.2 0.0 1.9 2 0 0 2 2 2 0 PET Domain SDA1 PF05285.12 KIK44905.1 - 0.00053 19.5 16.8 0.00057 19.4 16.8 1.1 1 0 0 1 1 1 1 SDA1 NOA36 PF06524.12 KIK44905.1 - 8.6 5.6 32.4 15 4.8 32.4 1.4 1 0 0 1 1 1 0 NOA36 protein DUF5500 PF17604.2 KIK44906.1 - 0.11 12.6 0.7 1.6 8.8 0.0 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5500) DUF2053 PF09767.9 KIK44908.1 - 0.032 14.4 9.1 0.063 13.4 9.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2053) Vps36_ESCRT-II PF11605.8 KIK44909.1 - 0.00097 19.3 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.6 KIK44909.1 - 0.012 15.9 0.0 0.02 15.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial PH domain GRAM PF02893.20 KIK44909.1 - 0.02 14.8 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 GRAM domain Pkinase PF00069.25 KIK44910.1 - 2.4e-38 132.0 0.0 2.2e-22 79.7 0.0 3.5 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KIK44910.1 - 2.3e-10 40.2 0.0 6.4e-08 32.2 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KIK44910.1 - 0.0017 18.3 0.1 0.005 16.8 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KIK44910.1 - 0.041 13.5 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KIK44910.1 - 0.11 11.3 0.0 0.23 10.2 0.0 1.5 1 1 0 1 1 1 0 Fungal protein kinase UCH PF00443.29 KIK44911.1 - 1.2e-32 113.4 0.0 1.6e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIK44911.1 - 1.8e-05 24.5 1.0 1.8e-05 24.5 1.0 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF1992 PF09350.10 KIK44913.1 - 2e-21 75.9 0.1 4.5e-21 74.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) BRD4_CDT PF17105.5 KIK44913.1 - 0.064 12.9 3.8 0.16 11.6 3.8 1.7 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 WD40 PF00400.32 KIK44915.1 - 3.9e-84 274.3 31.3 4.3e-10 40.0 0.4 8.7 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK44915.1 - 9.2e-21 74.0 0.1 0.31 11.4 0.0 8.2 1 1 6 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK44915.1 - 7.3e-17 61.3 8.1 0.55 9.1 0.0 8.2 8 0 0 8 8 8 8 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK44915.1 - 1.1e-12 47.5 14.1 3.2 7.8 0.1 8.5 8 0 0 8 8 8 5 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK44915.1 - 4.6e-06 26.2 0.0 11 5.2 0.0 6.0 5 1 1 7 7 7 0 WD40-like domain AAA_16 PF13191.6 KIK44915.1 - 5.1e-05 23.7 0.1 0.00015 22.2 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK44915.1 - 0.00024 21.1 0.0 0.00059 19.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Frtz PF11768.8 KIK44915.1 - 0.00055 18.4 0.0 7 4.8 0.0 4.8 3 2 3 6 6 6 1 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 KIK44915.1 - 0.0022 17.4 12.2 7.8 5.7 0.1 6.7 7 1 0 7 7 7 2 Neuroblastoma-amplified sequence, N terminal NB-ARC PF00931.22 KIK44915.1 - 0.013 14.7 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.17 KIK44915.1 - 0.023 13.8 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.29 KIK44915.1 - 0.088 13.2 0.0 0.28 11.6 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK44915.1 - 0.11 12.9 0.1 0.6 10.5 0.0 2.3 2 0 0 2 2 2 0 RNA helicase RAI1 PF08652.11 KIK44915.1 - 0.12 12.6 0.0 91 3.4 0.0 4.1 4 0 0 4 4 4 0 RAI1 like PD-(D/E)XK nuclease PQQ_2 PF13360.6 KIK44915.1 - 1.7 8.2 9.0 42 3.6 1.1 3.8 1 1 1 2 2 2 0 PQQ-like domain PQQ_3 PF13570.6 KIK44915.1 - 5.7 7.6 11.6 1.9e+02 2.7 0.0 6.4 8 0 0 8 8 7 0 PQQ-like domain Aldedh PF00171.22 KIK44917.1 - 2.2e-103 346.3 0.0 3e-103 345.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BTB PF00651.31 KIK44918.1 - 3.5e-09 36.9 0.0 7.5e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Pro_isomerase PF00160.21 KIK44919.1 - 4.1e-40 137.6 0.0 6.5e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KIK44919.1 - 6.3e-16 58.0 0.0 1.2e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PLAC8 PF04749.17 KIK44921.1 - 0.056 14.5 0.0 0.068 14.2 0.0 1.2 1 0 0 1 1 1 0 PLAC8 family AftA_N PF12250.8 KIK44922.1 - 0.027 13.2 2.6 0.033 13.0 2.6 1.1 1 0 0 1 1 1 0 Arabinofuranosyltransferase N terminal Cyt-b5 PF00173.28 KIK44924.1 - 3.7e-23 81.5 0.1 5.2e-23 81.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HIG_1_N PF04588.13 KIK44925.1 - 0.0029 17.8 0.2 0.0069 16.6 0.1 1.8 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Nucleoporin2 PF04096.14 KIK44926.1 - 4.8e-41 140.3 0.0 7.4e-41 139.7 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KIK44926.1 - 2.3e-12 47.6 120.0 7.7e-07 29.9 30.4 9.6 3 3 7 10 10 10 7 Nucleoporin FG repeat region RNA_pol_Rpb2_6 PF00562.28 KIK44927.1 - 9.6e-113 377.2 0.0 1.9e-112 376.2 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KIK44927.1 - 6.4e-31 107.5 0.0 1.1e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KIK44927.1 - 1.9e-28 98.4 0.0 4.2e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 KIK44927.1 - 1.7e-24 85.6 0.0 4.3e-24 84.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 KIK44927.1 - 1.1e-19 70.8 0.0 2e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KIK44927.1 - 8.2e-19 67.8 0.2 5.1e-15 55.6 0.2 2.9 3 0 0 3 3 3 2 RNA polymerase Rpb2, domain 7 zf-H2C2_2 PF13465.6 KIK44929.1 - 0.00028 21.2 2.2 0.55 10.8 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger double domain FOXP-CC PF16159.5 KIK44929.1 - 0.0012 19.4 5.3 0.81 10.4 0.1 2.9 2 1 0 2 2 2 2 FOXP coiled-coil domain zf-C2H2 PF00096.26 KIK44929.1 - 0.01 16.3 0.3 0.01 16.3 0.3 2.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KIK44929.1 - 0.034 14.3 0.3 0.079 13.1 0.2 1.6 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 KIK44929.1 - 0.045 14.6 5.0 0.11 13.4 0.7 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Methyltransf_23 PF13489.6 KIK44931.1 - 4.8e-15 55.8 0.0 7.4e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK44931.1 - 1e-11 45.3 0.0 2.3e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK44931.1 - 4.9e-10 40.0 0.0 1.3e-09 38.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK44931.1 - 6.7e-10 39.6 0.0 1.6e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK44931.1 - 1.9e-07 31.0 0.0 2.6e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KIK44931.1 - 0.021 14.8 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KIK44931.1 - 0.064 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 KIK44931.1 - 0.098 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family FtsJ PF01728.19 KIK44931.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.7 3 0 0 3 3 3 0 FtsJ-like methyltransferase RrnaAD PF00398.20 KIK44931.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Abhydrolase_2 PF02230.16 KIK44932.1 - 6.1e-44 150.4 0.0 7.6e-43 146.8 0.0 1.9 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 KIK44932.1 - 9.8e-06 25.4 0.0 1.7e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KIK44932.1 - 1.8e-05 25.5 6.9 2.9e-05 24.8 6.9 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK44932.1 - 0.00031 20.1 0.0 1.7 7.8 0.0 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK44932.1 - 0.015 15.0 0.0 3 7.4 0.1 2.4 2 1 0 2 2 2 0 alpha/beta hydrolase fold Cutinase PF01083.22 KIK44932.1 - 0.045 13.7 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_3 PF07859.13 KIK44932.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.12 KIK44932.1 - 0.19 10.4 0.1 0.28 9.8 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) tRNA_m1G_MT PF01746.21 KIK44933.1 - 1.3e-26 93.6 0.1 3.3e-26 92.2 0.1 1.7 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Kelch_1 PF01344.25 KIK44933.1 - 0.16 11.6 0.2 0.35 10.5 0.2 1.5 1 0 0 1 1 1 0 Kelch motif DNA_pol_phi PF04931.13 KIK44933.1 - 0.22 9.6 2.2 0.38 8.8 2.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi Abhydrolase_2 PF02230.16 KIK44934.1 - 7.5e-47 159.9 0.2 1.3e-45 155.9 0.2 2.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 KIK44934.1 - 8.7e-08 32.1 0.0 1.5e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Cutinase PF01083.22 KIK44934.1 - 0.00014 21.9 0.0 0.00063 19.7 0.0 1.9 2 0 0 2 2 2 1 Cutinase Abhydrolase_6 PF12697.7 KIK44934.1 - 0.00017 22.3 0.8 0.00031 21.4 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KIK44934.1 - 0.0014 18.6 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK44934.1 - 0.0023 17.2 1.4 1.2 8.3 0.1 3.2 2 1 1 3 3 3 2 Serine aminopeptidase, S33 AXE1 PF05448.12 KIK44934.1 - 0.0057 15.4 0.0 0.01 14.5 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.25 KIK44934.1 - 0.035 14.0 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PAF-AH_p_II PF03403.13 KIK44934.1 - 0.048 12.2 0.0 0.16 10.4 0.0 1.7 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II PE-PPE PF08237.11 KIK44934.1 - 0.048 13.2 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_2 PF02230.16 KIK44935.1 - 3.4e-32 112.0 0.0 9e-32 110.6 0.0 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 KIK44935.1 - 0.016 14.9 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Aldo_ket_red PF00248.21 KIK44936.1 - 9.4e-45 153.0 0.0 2.5e-42 145.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family ELL PF10390.9 KIK44936.1 - 0.12 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL MWFE PF15879.5 KIK44937.1 - 6.1e-23 80.7 0.1 7.4e-23 80.5 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit BPL_LplA_LipB PF03099.19 KIK44938.1 - 4.5e-06 26.6 0.0 7.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.9 KIK44938.1 - 0.00031 20.7 0.0 0.00068 19.6 0.0 1.6 1 1 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus WAC_Acf1_DNA_bd PF10537.9 KIK44938.1 - 0.087 13.3 0.0 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal CX9C PF16860.5 KIK44939.1 - 5.1e-06 26.4 7.4 0.0018 18.3 4.2 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 KIK44939.1 - 0.0016 18.5 5.4 0.0016 18.5 5.4 2.5 3 0 0 3 3 3 2 CHCH domain PBP_GOBP PF01395.22 KIK44939.1 - 0.01 16.0 0.5 0.018 15.2 0.5 1.4 1 0 0 1 1 1 0 PBP/GOBP family YqzH PF14164.6 KIK44939.1 - 0.11 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 YqzH-like protein Pet191_N PF10203.9 KIK44939.1 - 5.6 7.3 11.4 58 4.1 0.2 3.0 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 DUF498 PF04430.14 KIK44941.1 - 4.2e-35 120.1 0.0 4.7e-35 120.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) MAS20 PF02064.15 KIK44942.1 - 1.4e-39 135.1 0.0 8.5e-39 132.6 0.0 2.2 2 0 0 2 2 2 1 MAS20 protein import receptor SET PF00856.28 KIK44942.1 - 1.4e-07 32.0 0.0 3.5e-07 30.8 0.0 1.6 1 1 0 1 1 1 1 SET domain Pkinase PF00069.25 KIK44944.1 - 4e-19 69.0 0.0 4.7e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK44944.1 - 3.9e-11 42.7 0.0 4.4e-11 42.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK44944.1 - 0.003 16.9 0.0 0.0036 16.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIK44944.1 - 0.012 14.6 0.0 0.012 14.5 0.0 1.0 1 0 0 1 1 1 0 Haspin like kinase domain NHL PF01436.21 KIK44944.1 - 0.021 14.9 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 NHL repeat APH PF01636.23 KIK44944.1 - 0.025 14.5 0.2 0.03 14.2 0.2 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KIK44944.1 - 0.14 11.5 0.4 0.15 11.4 0.4 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SMK-1 PF04802.15 KIK44945.1 - 6e-74 248.0 1.1 9.8e-74 247.3 1.1 1.4 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 ACP_syn_III PF08545.10 KIK44945.1 - 0.018 14.9 0.1 8.2 6.4 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III F-box PF00646.33 KIK44946.1 - 2.5e-10 40.0 0.1 1e-09 38.0 0.1 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK44946.1 - 3e-07 30.2 0.1 3e-07 30.2 0.1 2.4 3 0 0 3 3 3 1 F-box-like GATA PF00320.27 KIK44950.1 - 3e-08 33.1 5.0 5.7e-08 32.2 4.2 1.9 2 0 0 2 2 2 1 GATA zinc finger ArfGap PF01412.18 KIK44950.1 - 0.42 10.7 0.1 0.42 10.7 0.1 1.9 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf ING PF12998.7 KIK44952.1 - 4.6e-14 52.8 1.4 6.5e-14 52.3 1.4 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KIK44952.1 - 0.0011 18.8 8.7 0.0017 18.2 8.7 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KIK44952.1 - 0.0033 17.7 0.5 0.006 16.8 0.5 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain Rhomboid PF01694.22 KIK44956.1 - 1.3e-06 28.5 8.8 2e-06 27.9 8.8 1.3 1 0 0 1 1 1 1 Rhomboid family CUE PF02845.16 KIK44956.1 - 5.3e-06 26.0 0.1 9.2e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 CUE domain DER1 PF04511.15 KIK44956.1 - 0.00015 21.8 1.0 0.00021 21.3 1.0 1.2 1 0 0 1 1 1 1 Der1-like family eIF-3_zeta PF05091.12 KIK44957.1 - 3e-210 699.7 0.0 3.4e-210 699.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RRM_1 PF00076.22 KIK44958.1 - 3.9e-18 65.0 0.0 6.6e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK44958.1 - 7.5e-08 32.4 0.0 1.5e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 KIK44958.1 - 0.00024 20.7 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIK44958.1 - 0.0014 18.7 1.3 0.55 10.3 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif DUF1314 PF07013.11 KIK44958.1 - 0.0096 15.8 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1314) CNH PF00780.22 KIK44961.1 - 0.0002 21.1 0.0 0.088 12.4 0.0 2.3 2 0 0 2 2 2 2 CNH domain TRP PF06011.12 KIK44962.1 - 2.7e-32 112.0 13.1 8.4e-32 110.4 13.1 1.7 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel E1_DerP2_DerF2 PF02221.15 KIK44962.1 - 9.8e-08 32.5 0.2 1.6e-07 31.8 0.2 1.3 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 KIK44962.1 - 0.03 14.7 0.4 0.062 13.7 0.4 1.5 1 0 0 1 1 1 0 ML-like domain LETM1 PF07766.13 KIK44964.1 - 0.017 14.5 0.0 0.02 14.2 0.0 1.0 1 0 0 1 1 1 0 LETM1-like protein WD40 PF00400.32 KIK44968.1 - 3e-40 135.4 18.4 3.3e-07 30.9 0.0 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK44968.1 - 1.1e-17 64.0 6.4 5.7e-05 23.3 0.1 6.0 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK44968.1 - 2.8e-09 36.2 5.4 0.16 10.6 0.2 4.7 2 2 2 5 5 5 4 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KIK44968.1 - 9.2e-08 32.4 6.4 1 10.0 0.5 5.4 5 0 0 5 5 5 3 PQQ-like domain Ge1_WD40 PF16529.5 KIK44968.1 - 3e-06 26.4 0.1 0.7 8.8 0.0 4.8 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 KIK44968.1 - 7.8e-06 25.6 1.8 3 7.9 0.0 4.8 4 0 0 4 4 4 2 PQQ enzyme repeat WD40_like PF17005.5 KIK44968.1 - 0.00016 21.1 0.0 0.0014 18.0 0.0 2.3 1 1 1 2 2 2 1 WD40-like domain PD40 PF07676.12 KIK44968.1 - 0.0082 16.1 0.0 32 4.6 0.0 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RAB3GAP2_N PF14655.6 KIK44968.1 - 0.063 12.5 0.1 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Mucin PF01456.17 KIK44969.1 - 0.0038 17.2 5.7 0.0051 16.8 5.7 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein Minor_capsid_1 PF10665.9 KIK44970.1 - 0.023 14.9 0.0 0.023 14.9 0.0 1.1 1 0 0 1 1 1 0 Minor capsid protein UL42 PF17638.2 KIK44972.1 - 0.13 12.2 0.1 0.13 12.2 0.1 2.0 2 1 1 3 3 3 0 HCMV UL42 Cu2_monoox_C PF03712.15 KIK44973.1 - 0.17 11.4 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain WD40 PF00400.32 KIK44975.1 - 2e-35 120.2 15.1 1.9e-06 28.5 2.6 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK44975.1 - 1.2e-15 57.5 6.6 4.8e-06 26.8 0.2 5.2 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK44975.1 - 8.1e-08 32.4 1.2 4.6e-06 26.6 0.3 2.6 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK44975.1 - 2.7e-06 26.3 7.4 0.67 8.5 0.0 4.5 3 1 2 5 5 5 3 Nucleoporin Nup120/160 PQQ PF01011.21 KIK44975.1 - 0.00053 19.8 1.1 1.4 9.0 0.0 4.5 4 1 0 4 4 4 1 PQQ enzyme repeat WD40_like PF17005.5 KIK44975.1 - 0.0025 17.2 0.0 1.1 8.6 0.0 3.2 3 0 0 3 3 3 1 WD40-like domain Nbas_N PF15492.6 KIK44975.1 - 0.0031 16.9 0.4 0.15 11.3 0.1 3.1 2 2 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 KIK44975.1 - 0.01 14.9 0.0 0.7 8.8 0.0 3.2 1 1 3 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KIK44975.1 - 0.011 14.7 3.5 0.64 8.9 0.2 3.3 1 1 2 3 3 3 0 Partner and localizer of BRCA2 WD40 domain BRK PF07533.16 KIK44975.1 - 0.074 12.7 0.2 25 4.6 0.0 3.6 4 0 0 4 4 4 0 BRK domain PepSY PF03413.19 KIK44975.1 - 0.47 11.1 2.8 20 5.8 0.2 3.2 3 2 0 3 3 2 0 Peptidase propeptide and YPEB domain DUF1658 PF07871.11 KIK44976.1 - 0.037 13.9 1.7 0.037 13.9 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) WD40 PF00400.32 KIK44977.1 - 1.2e-38 130.4 26.8 1e-06 29.3 3.3 8.3 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK44977.1 - 1.3e-14 54.2 6.1 0.00051 20.3 0.1 6.2 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KIK44977.1 - 0.00025 19.7 0.1 0.98 7.9 0.1 3.1 2 1 1 3 3 3 3 Cytochrome D1 heme domain Nup160 PF11715.8 KIK44977.1 - 0.0016 17.1 6.3 0.44 9.1 0.1 4.1 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK44977.1 - 0.0029 16.6 0.1 4 6.3 0.0 3.9 1 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK44977.1 - 0.0077 16.2 0.0 13 5.8 0.0 3.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK44977.1 - 0.034 13.5 0.0 0.15 11.4 0.0 2.1 1 1 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK44977.1 - 0.059 12.7 0.0 0.22 10.8 0.0 1.9 1 1 0 1 1 1 0 WD40-like domain PQQ_3 PF13570.6 KIK44977.1 - 0.19 12.2 6.6 1.5 9.4 1.0 4.1 4 1 1 5 5 5 0 PQQ-like domain PQQ PF01011.21 KIK44977.1 - 0.83 9.7 3.7 5.3 7.2 0.2 3.6 4 0 0 4 4 4 0 PQQ enzyme repeat AAA PF00004.29 KIK44978.1 - 4e-05 24.0 0.0 7.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIK44978.1 - 0.0019 18.2 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KIK44978.1 - 0.0052 16.0 0.0 0.009 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 KIK44978.1 - 0.0058 17.0 0.1 0.017 15.5 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KIK44978.1 - 0.032 14.0 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain MCM PF00493.23 KIK44978.1 - 0.048 12.8 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain TsaE PF02367.17 KIK44978.1 - 0.052 13.6 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 KIK44978.1 - 0.085 12.6 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 KIK44978.1 - 0.18 12.3 0.0 0.26 11.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter WD40 PF00400.32 KIK44979.1 - 1.3e-35 120.8 11.2 1.9e-07 31.6 1.2 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK44979.1 - 4.8e-17 62.0 3.1 2.5e-06 27.7 0.1 5.1 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK44979.1 - 8.9e-09 34.7 0.0 0.016 14.2 0.0 4.2 1 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK44979.1 - 8.4e-08 32.3 0.5 4.3e-06 26.7 0.3 2.5 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK44979.1 - 1.2e-05 24.8 0.0 0.00024 20.5 0.0 2.1 2 0 0 2 2 2 1 WD40-like domain Nbas_N PF15492.6 KIK44979.1 - 0.00011 21.7 0.2 0.11 11.8 0.0 3.0 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK44979.1 - 0.00013 20.8 5.2 0.59 8.7 0.1 3.6 1 1 3 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.12 KIK44979.1 - 0.00016 21.5 0.0 6.3 6.9 0.0 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KIK44979.1 - 0.0079 14.8 0.2 0.17 10.3 0.0 2.0 1 1 1 2 2 2 1 Cytochrome D1 heme domain ELYS-bb PF16687.5 KIK44979.1 - 0.026 13.1 0.0 0.14 10.8 0.0 2.0 1 1 0 2 2 2 0 beta-propeller of ELYS nucleoporin PALB2_WD40 PF16756.5 KIK44979.1 - 0.048 12.6 1.8 0.53 9.1 0.8 2.4 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain RAB3GAP2_N PF14655.6 KIK44979.1 - 0.12 11.6 0.2 1.4 8.1 0.0 2.4 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Elongin_A PF06881.11 KIK44983.1 - 1.2e-22 80.5 0.4 1.2e-22 80.5 0.4 1.5 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A MRP-L46 PF11788.8 KIK44983.1 - 0.0042 17.8 1.9 0.0085 16.8 1.9 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 GATase_6 PF13522.6 KIK44984.1 - 8.5e-13 48.7 0.0 1.8e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KIK44984.1 - 6.6e-09 35.7 0.0 1.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KIK44984.1 - 1.9e-08 34.0 0.1 3.5e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KIK44984.1 - 9.2e-05 21.5 0.0 0.00063 18.7 0.0 2.0 1 1 1 2 2 2 1 Glutamine amidotransferases class-II AP_endonuc_2 PF01261.24 KIK44984.1 - 0.09 12.2 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Usp PF00582.26 KIK44984.1 - 0.12 12.8 0.0 1.3 9.6 0.0 2.3 2 0 0 2 2 2 0 Universal stress protein family PorB PF11565.8 KIK44984.1 - 0.17 12.3 0.0 0.49 10.8 0.0 1.7 1 0 0 1 1 1 0 Alpha helical Porin B WD40 PF00400.32 KIK44988.1 - 7.3e-43 143.7 21.7 7.6e-08 32.9 4.6 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK44988.1 - 5.6e-16 58.6 10.3 5.6e-08 33.0 0.3 5.7 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK44988.1 - 1.8e-08 34.5 3.7 1.2e-06 28.5 1.2 2.8 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK44988.1 - 6.3e-07 28.4 7.7 0.21 10.2 0.2 4.4 2 1 3 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK44988.1 - 9.3e-05 21.9 0.0 0.084 12.2 0.0 4.1 2 1 3 5 5 5 1 WD40-like domain Ge1_WD40 PF16529.5 KIK44988.1 - 0.00065 18.8 0.0 1.4 7.8 0.0 3.9 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein RAB3GAP2_N PF14655.6 KIK44988.1 - 0.0083 15.4 0.0 0.038 13.2 0.0 1.9 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Hira PF07569.11 KIK44988.1 - 0.014 15.1 1.9 0.98 9.1 0.3 3.8 3 1 0 4 4 4 0 TUP1-like enhancer of split PQQ PF01011.21 KIK44988.1 - 0.024 14.6 4.6 5 7.2 0.7 4.6 5 0 0 5 5 5 0 PQQ enzyme repeat Nbas_N PF15492.6 KIK44988.1 - 0.028 13.8 0.4 0.86 8.9 0.0 3.2 2 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal PQQ_3 PF13570.6 KIK44988.1 - 0.046 14.2 4.9 2.8 8.5 0.1 3.4 2 1 0 2 2 2 0 PQQ-like domain PALB2_WD40 PF16756.5 KIK44988.1 - 0.049 12.6 7.6 0.11 11.4 0.3 3.4 2 1 2 4 4 4 0 Partner and localizer of BRCA2 WD40 domain WD40 PF00400.32 KIK44990.1 - 2e-43 145.5 28.0 3e-08 34.2 1.9 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK44990.1 - 1.2e-15 57.6 7.5 1.3e-07 31.8 0.2 5.6 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK44990.1 - 1.1e-05 24.3 8.5 0.036 12.7 0.8 3.9 1 1 3 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK44990.1 - 2.1e-05 24.0 0.0 0.011 15.1 0.0 3.5 3 1 1 4 4 4 1 WD40-like domain Ge1_WD40 PF16529.5 KIK44990.1 - 0.00032 19.8 0.1 0.17 10.8 0.0 3.7 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 KIK44990.1 - 0.0026 17.6 0.3 1.6 8.8 0.0 4.4 4 0 0 4 4 4 1 PQQ enzyme repeat Cytochrom_D1 PF02239.16 KIK44990.1 - 0.0029 16.2 0.2 0.048 12.2 0.1 2.6 3 0 0 3 3 3 1 Cytochrome D1 heme domain PQQ_3 PF13570.6 KIK44990.1 - 0.014 15.8 8.1 8.3 7.0 1.9 5.0 4 1 1 5 5 5 0 PQQ-like domain RAB3GAP2_N PF14655.6 KIK44990.1 - 0.026 13.8 0.0 0.07 12.4 0.0 1.7 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PD40 PF07676.12 KIK44990.1 - 0.035 14.0 0.0 87 3.2 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK44990.1 - 0.052 12.9 0.8 0.39 10.0 0.1 2.6 1 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.9 KIK44990.1 - 0.054 13.2 4.5 0.75 9.5 1.8 3.1 1 1 2 3 3 3 0 Lipoprotein LpqB beta-propeller domain DUF4402 PF14352.6 KIK44990.1 - 0.14 12.8 0.1 0.95 10.1 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4402) Gemini_C4 PF01492.17 KIK44994.1 - 0.048 13.6 2.7 0.83 9.6 0.2 2.2 1 1 1 2 2 2 0 Geminivirus C4 protein WD40 PF00400.32 KIK44996.1 - 2.5e-37 126.2 6.8 2.1e-06 28.4 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK44996.1 - 2.7e-10 40.4 2.3 0.33 11.3 0.0 5.4 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK44996.1 - 4.7e-07 29.9 0.3 0.015 15.2 0.1 3.4 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK44996.1 - 0.00032 19.5 4.0 0.28 9.8 0.6 2.8 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK44996.1 - 0.00058 18.9 6.1 0.2 10.6 0.3 3.9 2 2 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 KIK44996.1 - 0.002 17.3 3.0 0.061 12.4 0.1 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1513) WD40_like PF17005.5 KIK44996.1 - 0.17 11.2 0.0 20 4.4 0.1 2.8 3 1 1 4 4 4 0 WD40-like domain WD40 PF00400.32 KIK44998.1 - 0.0027 18.5 3.3 0.13 13.1 0.0 4.0 5 0 0 5 5 5 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 KIK44998.1 - 0.0058 16.7 0.0 1.8 8.6 0.0 2.7 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region SGL PF08450.12 KIK44998.1 - 0.044 13.4 0.5 0.32 10.5 0.1 2.1 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 KIK44998.1 - 0.25 11.7 1.3 3.5 8.2 0.4 2.7 2 0 0 2 2 2 0 Two component regulator propeller Kelch_4 PF13418.6 KIK44998.1 - 2.6 8.1 5.3 1.2 9.2 0.5 2.9 3 1 1 4 4 4 0 Galactose oxidase, central domain Chitin_synth_1 PF01644.17 KIK44999.1 - 8.2e-79 263.3 0.1 1.2e-78 262.7 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KIK44999.1 - 2.1e-28 98.1 0.1 4.3e-28 97.1 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KIK44999.1 - 1.7e-24 86.3 1.3 4.9e-18 65.0 0.1 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KIK44999.1 - 1.4e-05 25.1 1.2 1.4e-05 25.1 1.2 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 WD40 PF00400.32 KIK45004.1 - 4.1e-31 106.6 4.0 9.9e-05 23.0 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45004.1 - 7.4e-14 51.8 0.1 0.028 14.7 0.0 5.7 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK45004.1 - 1.7e-05 24.0 0.1 0.15 11.0 0.0 4.0 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Robl_LC7 PF03259.17 KIK45004.1 - 4.8e-05 23.1 0.3 0.36 10.6 0.0 3.3 3 0 0 3 3 3 3 Roadblock/LC7 domain PD40 PF07676.12 KIK45004.1 - 0.0063 16.4 0.0 4.7 7.3 0.0 4.4 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat TPR_8 PF13181.6 KIK45005.1 - 0.0011 19.0 0.5 0.042 14.1 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK45005.1 - 0.0013 18.7 4.7 0.088 13.0 0.5 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat F-box-like_2 PF13013.6 KIK45005.1 - 0.0072 16.3 0.0 0.0087 16.0 0.0 1.2 1 0 0 1 1 1 1 F-box-like domain TPR_1 PF00515.28 KIK45005.1 - 0.11 12.4 2.4 2.9 7.9 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK45005.1 - 0.12 13.0 2.6 1.3 9.7 0.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIK45005.1 - 0.21 11.9 2.7 2.2 8.7 0.4 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat GH131_N PF18271.1 KIK45006.1 - 1.7e-85 286.8 0.0 1.9e-85 286.6 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Gln-synt_C PF00120.24 KIK45007.1 - 0.0014 17.7 0.0 0.0015 17.6 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain VEGF_C PF14554.6 KIK45008.1 - 3.9 7.6 12.6 5.4 7.2 0.6 2.3 2 0 0 2 2 2 0 VEGF heparin-binding domain zf-TAZ PF02135.16 KIK45009.1 - 0.044 14.2 6.2 0.082 13.4 6.2 1.3 1 0 0 1 1 1 0 TAZ zinc finger F-box-like PF12937.7 KIK45010.1 - 0.14 12.1 2.5 0.12 12.3 0.7 2.0 2 1 0 2 2 2 0 F-box-like Sugar_tr PF00083.24 KIK45018.1 - 4e-43 147.9 16.9 5.5e-43 147.5 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK45018.1 - 2.7e-20 72.6 24.7 3.7e-14 52.4 2.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Complex1_51K PF01512.17 KIK45019.1 - 2.3e-47 160.7 0.0 3.3e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KIK45019.1 - 3.3e-31 107.2 1.4 5.5e-31 106.5 0.3 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KIK45019.1 - 1.1e-08 34.8 0.0 2.8e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 SLBB domain DSPc PF00782.20 KIK45021.1 - 2e-32 111.8 0.0 2.6e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KIK45021.1 - 0.00033 20.9 0.0 0.00053 20.3 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KIK45021.1 - 0.071 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KIK45021.1 - 0.17 12.0 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Ras PF00071.22 KIK45023.1 - 1.4e-54 184.1 0.0 1.6e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK45023.1 - 2.3e-21 76.2 0.0 3.3e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK45023.1 - 2.1e-07 30.6 0.0 3.8e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KIK45023.1 - 0.0082 15.6 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AKAP7_NLS PF10469.9 KIK45024.1 - 2.1e-28 99.7 0.0 2.5e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 KIK45024.1 - 5.4e-05 23.2 0.0 0.0047 16.9 0.0 2.0 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily Asp PF00026.23 KIK45025.1 - 6.3e-37 127.7 0.0 9.7e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK45025.1 - 2.8e-07 30.9 0.5 2.9e-05 24.4 0.5 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal AAA_16 PF13191.6 KIK45029.1 - 1.8e-07 31.7 0.1 5.8e-07 30.0 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK45029.1 - 3.1e-06 27.2 0.0 7.3e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 KIK45029.1 - 0.00016 21.6 0.0 0.00052 20.0 0.0 1.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA PF00004.29 KIK45029.1 - 0.0011 19.3 0.0 0.0043 17.5 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KIK45029.1 - 0.007 16.3 0.1 0.27 11.1 0.0 2.8 3 0 0 3 3 3 1 Rad17 P-loop domain RNA_helicase PF00910.22 KIK45029.1 - 0.01 16.2 0.0 0.033 14.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_PrkA PF08298.11 KIK45029.1 - 0.024 13.6 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Parvo_NS1 PF01057.17 KIK45029.1 - 0.03 13.4 0.3 0.19 10.8 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 APS_kinase PF01583.20 KIK45029.1 - 0.036 14.0 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase PhoU PF01895.19 KIK45029.1 - 0.051 14.0 2.1 1.8 9.1 0.1 3.3 3 0 0 3 3 3 0 PhoU domain Vps5 PF09325.10 KIK45029.1 - 0.057 13.0 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Vps5 C terminal like NB-ARC PF00931.22 KIK45029.1 - 0.062 12.5 0.0 0.15 11.2 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain PhoU_div PF01865.16 KIK45029.1 - 0.085 12.2 0.7 0.21 10.9 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF47 Asp5 PF17000.5 KIK45030.1 - 0.077 13.1 0.0 0.086 13.0 0.0 1.2 1 0 0 1 1 1 0 Accessory secretory protein Sec, Asp5 ABC_membrane PF00664.23 KIK45032.1 - 3.1e-54 184.5 33.4 9e-31 107.5 15.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK45032.1 - 7.1e-53 178.8 0.0 1.3e-28 100.2 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIK45032.1 - 5e-07 29.4 6.1 0.01 15.3 2.7 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIK45032.1 - 4.2e-06 26.8 5.0 0.11 12.3 0.1 3.8 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KIK45032.1 - 4.3e-06 26.8 2.8 0.043 13.9 0.2 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KIK45032.1 - 1e-05 26.0 0.3 0.09 13.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KIK45032.1 - 3.3e-05 23.6 2.3 0.066 13.0 0.1 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KIK45032.1 - 0.0004 21.0 0.2 1.1 9.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KIK45032.1 - 0.001 19.0 3.2 0.13 12.1 0.3 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 KIK45032.1 - 0.0013 18.5 0.1 0.048 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIK45032.1 - 0.0093 15.6 0.5 0.92 9.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KIK45032.1 - 0.022 15.0 3.6 2.2 8.5 0.1 3.3 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 KIK45032.1 - 0.027 14.4 2.2 14 5.6 0.0 3.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 KIK45032.1 - 0.042 14.0 2.5 7.3 6.7 0.3 3.1 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 KIK45032.1 - 0.046 13.9 0.8 11 6.3 0.2 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 KIK45032.1 - 0.054 13.2 2.9 4.8 6.8 0.1 2.9 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KIK45032.1 - 0.063 13.2 1.1 0.55 10.1 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.23 KIK45032.1 - 0.067 13.2 5.3 0.65 10.0 0.9 2.7 2 0 0 2 2 2 0 Dynamin family PRIMA1 PF16101.5 KIK45032.1 - 0.068 13.2 0.7 0.15 12.1 0.7 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Zeta_toxin PF06414.12 KIK45032.1 - 0.091 12.0 0.7 4.1 6.6 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 KIK45032.1 - 0.091 12.3 1.0 2.2 7.7 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 KIK45032.1 - 0.13 11.8 1.9 1 8.9 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 KIK45032.1 - 0.22 11.6 3.9 0.98 9.5 0.6 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 KIK45032.1 - 0.3 10.0 3.0 4.1 6.2 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.17 KIK45032.1 - 0.45 10.3 2.2 15 5.3 0.2 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 KIK45032.1 - 0.61 9.2 2.0 7.9 5.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain MeaB PF03308.16 KIK45032.1 - 3.6 6.5 5.8 8.1 5.3 0.6 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF4116 PF13475.6 KIK45033.1 - 0.066 13.0 0.2 0.11 12.2 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4116) NADH-u_ox-rdase PF10785.9 KIK45034.1 - 0.0083 16.8 0.3 0.011 16.4 0.3 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit FixH PF05751.11 KIK45035.1 - 0.091 12.8 0.5 0.23 11.5 0.5 1.6 1 0 0 1 1 1 0 FixH SecG PF03840.14 KIK45036.1 - 0.045 13.8 1.2 0.045 13.8 1.2 2.9 3 1 0 3 3 3 0 Preprotein translocase SecG subunit Ank_5 PF13857.6 KIK45037.1 - 2.3e-19 69.2 6.0 3.1e-07 30.5 0.2 5.5 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK45037.1 - 1.6e-17 63.8 0.2 1.1e-05 26.0 0.0 4.4 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK45037.1 - 4.4e-14 52.6 5.8 0.0012 19.4 0.0 6.0 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK45037.1 - 7.3e-13 47.5 2.2 0.0052 17.2 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KIK45037.1 - 4.4e-09 36.4 6.9 0.005 17.2 0.1 6.5 6 0 0 6 6 6 2 Ankyrin repeat TAP_C PF03943.13 KIK45038.1 - 3.9e-14 52.0 0.0 8.5e-14 50.9 0.0 1.6 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.20 KIK45038.1 - 0.00069 20.2 0.0 0.035 14.7 0.0 2.3 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain LRR_9 PF14580.6 KIK45038.1 - 0.001 18.6 0.1 0.0018 17.8 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KIK45038.1 - 0.0022 18.4 9.8 0.019 15.4 5.5 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) UBA_4 PF14555.6 KIK45038.1 - 0.05 13.4 0.1 0.24 11.3 0.1 2.2 2 0 0 2 2 2 0 UBA-like domain LRR_8 PF13855.6 KIK45038.1 - 1.5 8.6 9.8 11 5.8 9.2 2.5 1 1 0 1 1 1 0 Leucine rich repeat HTH_psq PF05225.16 KIK45039.1 - 0.002 17.8 0.1 0.0025 17.5 0.1 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_1 PF03184.19 KIK45040.1 - 1.7e-12 47.4 0.0 4.2e-12 46.1 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease MlaA PF04333.13 KIK45040.1 - 0.022 14.5 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 MlaA lipoprotein Shugoshin_N PF07558.11 KIK45040.1 - 0.036 13.9 0.1 0.074 12.9 0.1 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region SnAC PF14619.6 KIK45040.1 - 0.26 11.9 2.1 0.7 10.5 2.1 1.7 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex YabA PF06156.13 KIK45040.1 - 3.4 8.3 5.4 4.6 7.9 3.8 2.1 2 1 0 2 2 2 0 Initiation control protein YabA zf-C2H2_4 PF13894.6 KIK45041.1 - 0.00032 21.3 3.9 0.12 13.3 0.5 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK45041.1 - 0.0083 16.5 8.0 0.013 15.9 0.2 3.3 3 1 0 3 3 3 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 KIK45041.1 - 0.015 15.9 1.8 0.025 15.2 0.5 1.8 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 KIK45041.1 - 0.021 15.2 1.2 3.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Myb_DNA-binding PF00249.31 KIK45042.1 - 1.6e-05 25.0 1.9 3.1e-05 24.1 1.9 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain CDC45 PF02724.14 KIK45042.1 - 0.36 9.1 3.6 0.52 8.5 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein BSP_II PF05432.11 KIK45042.1 - 0.62 9.7 10.2 0.03 14.0 3.2 2.0 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) PRP38_assoc PF12871.7 KIK45042.1 - 9.7 6.9 17.3 2.3 8.9 12.5 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term GFA PF04828.14 KIK45043.1 - 3.6e-11 43.3 3.5 5.9e-11 42.6 3.5 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme SGL PF08450.12 KIK45045.1 - 6e-05 22.8 0.0 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region DUF4645 PF15488.6 KIK45045.1 - 0.032 13.7 0.2 6.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4645) Str_synth PF03088.16 KIK45045.1 - 0.15 12.2 0.0 0.76 9.9 0.0 2.0 2 0 0 2 2 2 0 Strictosidine synthase DUF848 PF05852.11 KIK45048.1 - 0.11 12.6 2.1 0.22 11.6 2.1 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) LRR_6 PF13516.6 KIK45051.1 - 0.00013 21.7 0.2 0.0046 16.9 0.0 2.9 3 0 0 3 3 3 1 Leucine Rich repeat Ras PF00071.22 KIK45055.1 - 0.045 13.3 0.1 0.09 12.4 0.0 1.6 2 0 0 2 2 2 0 Ras family Peptidase_M13_N PF05649.13 KIK45057.1 - 1.2e-20 74.6 0.0 1.5e-20 74.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 DGF-1_C PF11040.8 KIK45058.1 - 0.071 13.1 2.6 0.21 11.6 2.6 1.8 1 1 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Muskelin_N PF06588.11 KIK45059.1 - 1.4e-26 93.6 0.1 1.7e-26 93.4 0.1 1.1 1 0 0 1 1 1 1 Muskelin N-terminus PFK PF00365.20 KIK45061.1 - 1.4e-182 605.4 0.3 1.1e-98 330.1 0.1 2.9 2 1 0 2 2 2 2 Phosphofructokinase RQC PF09382.10 KIK45061.1 - 0.095 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 RQC domain Amino_oxidase PF01593.24 KIK45062.1 - 3.6e-38 132.0 0.0 6.9e-38 131.1 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK45062.1 - 8.3e-12 45.2 0.0 2.2e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KIK45062.1 - 0.00064 19.1 0.1 0.001 18.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIK45062.1 - 0.0021 17.7 0.0 0.0057 16.3 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK45062.1 - 0.0027 17.0 0.0 0.0046 16.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK45062.1 - 0.007 16.9 0.0 0.017 15.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK45062.1 - 0.048 12.7 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 KIK45062.1 - 0.12 11.1 0.1 0.17 10.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 KIK45062.1 - 0.16 11.0 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Na_Ca_ex PF01699.24 KIK45064.1 - 3.7e-43 147.1 45.9 2.8e-27 95.5 13.2 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF2771 PF10969.8 KIK45064.1 - 0.068 13.2 0.0 0.21 11.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2771) DGF-1_C PF11040.8 KIK45064.1 - 0.22 11.5 1.3 0.4 10.7 0.1 2.0 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Vps36-NZF-N PF16988.5 KIK45065.1 - 0.0055 16.1 0.4 0.0071 15.7 0.4 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain TOM13 PF08219.11 KIK45066.1 - 6.5e-13 48.5 0.0 2.3e-12 46.7 0.0 2.0 1 0 0 1 1 1 1 Outer membrane protein TOM13 DUF4407 PF14362.6 KIK45066.1 - 0.084 12.2 1.1 0.11 11.8 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GrpE PF01025.19 KIK45066.1 - 0.27 10.9 5.5 0.42 10.3 5.5 1.2 1 0 0 1 1 1 0 GrpE TPK_catalytic PF04263.16 KIK45067.1 - 3.2e-36 124.0 0.0 4.5e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KIK45067.1 - 4.8e-21 74.2 0.3 7.1e-21 73.7 0.3 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain ThiS PF02597.20 KIK45068.1 - 3.4e-06 27.6 0.0 5e-06 27.1 0.0 1.3 1 1 0 1 1 1 1 ThiS family Lactamase_B PF00753.27 KIK45069.1 - 8.1e-13 48.8 0.4 1.9e-12 47.6 0.4 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIK45069.1 - 0.041 13.4 0.2 0.094 12.2 0.2 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain DUF4078 PF13300.6 KIK45070.1 - 9.6e-19 67.5 1.8 9.6e-19 67.5 1.8 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4078) Malate_DH PF12434.8 KIK45070.1 - 3.5 7.7 5.8 0.35 10.9 0.2 2.3 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Ribosomal_L14 PF00238.19 KIK45071.1 - 2.8e-33 114.6 0.0 3.4e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e LRR_4 PF12799.7 KIK45072.1 - 2e-37 126.5 25.9 5.8e-08 32.9 0.3 6.5 4 1 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIK45072.1 - 1.1e-26 92.3 32.0 9.8e-12 44.5 5.0 6.2 3 2 4 7 7 7 6 Leucine rich repeat LRR_9 PF14580.6 KIK45072.1 - 5.4e-21 74.9 13.4 3.2e-10 39.8 1.5 4.0 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KIK45072.1 - 2.9e-06 27.0 26.1 35 5.5 0.1 10.2 10 0 0 10 10 10 1 Leucine Rich Repeat LRR_6 PF13516.6 KIK45072.1 - 0.00098 19.0 24.1 17 5.8 0.1 9.1 9 1 1 10 10 10 3 Leucine Rich repeat GATA PF00320.27 KIK45073.1 - 1.9e-13 49.8 3.5 1.9e-13 49.8 3.5 1.9 2 0 0 2 2 2 1 GATA zinc finger PAS_3 PF08447.12 KIK45073.1 - 0.013 15.8 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 PAS fold Ank_4 PF13637.6 KIK45074.1 - 1.4e-11 44.6 0.0 3.3e-06 27.5 0.0 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK45074.1 - 1.5e-09 38.3 0.0 5e-09 36.6 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIK45074.1 - 3.6e-09 36.7 0.0 2.7e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KIK45074.1 - 1.9e-06 28.1 0.0 0.022 15.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KIK45074.1 - 1.1e-05 25.4 0.0 0.0053 17.2 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat DUF2690 PF10901.8 KIK45074.1 - 0.064 13.6 0.1 0.55 10.6 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2690) PRMT5 PF05185.16 KIK45075.1 - 4.7e-65 218.7 0.0 9.9e-65 217.6 0.0 1.6 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 KIK45075.1 - 3e-62 210.1 0.2 9e-61 205.3 0.2 2.1 1 1 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 KIK45075.1 - 1.1e-56 191.4 0.0 1.7e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 KIK45075.1 - 0.0018 18.1 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 KIK45075.1 - 0.015 15.9 0.0 0.033 14.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Alpha_kinase PF02816.18 KIK45079.1 - 0.12 12.5 0.3 0.13 12.4 0.3 1.0 1 0 0 1 1 1 0 Alpha-kinase family BTB PF00651.31 KIK45081.1 - 0.0025 18.0 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain FlxA PF14282.6 KIK45082.1 - 0.25 11.3 1.4 0.75 9.8 1.4 1.8 1 1 0 1 1 1 0 FlxA-like protein ABC_tran_CTD PF16326.5 KIK45082.1 - 0.56 10.5 8.0 0.1 12.9 1.5 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain CE2_N PF17996.1 KIK45083.1 - 0.0018 18.2 0.6 2.3 8.2 0.1 2.5 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal CD99L2 PF12301.8 KIK45083.1 - 0.0032 17.8 1.0 0.0073 16.6 1.0 1.6 1 0 0 1 1 1 1 CD99 antigen like protein 2 Big_6 PF17936.1 KIK45083.1 - 0.23 11.8 3.5 1.5 9.2 0.3 3.0 3 0 0 3 3 3 0 Bacterial Ig domain Pkinase PF00069.25 KIK45085.1 - 3.9e-66 223.1 0.0 4.7e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK45085.1 - 3.3e-30 105.2 0.0 8.3e-30 103.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK45085.1 - 0.019 14.9 0.0 0.052 13.5 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK45085.1 - 0.023 13.6 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KIK45085.1 - 0.1 11.4 0.2 0.15 10.8 0.2 1.2 1 0 0 1 1 1 0 Fungal protein kinase Mito_carr PF00153.27 KIK45086.1 - 1.5e-69 230.0 7.5 1.3e-25 89.1 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KIK45086.1 - 0.00079 18.7 0.8 0.47 9.6 0.0 2.8 3 0 0 3 3 3 2 Gammaproteobacterial serine protease DUF3813 PF12758.7 KIK45086.1 - 0.066 13.5 0.5 0.12 12.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) RhoGAP PF00620.27 KIK45087.1 - 3.3e-30 104.9 0.0 5.7e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Glyco_hydro_63 PF03200.16 KIK45088.1 - 1.2e-09 37.5 9.6 7.9e-08 31.5 1.2 4.2 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain PH_10 PF15411.6 KIK45089.1 - 3e-38 130.9 0.0 6.9e-38 129.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KIK45089.1 - 3e-35 122.1 0.4 6.3e-35 121.1 0.4 1.6 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 KIK45089.1 - 9.1e-15 54.4 0.0 2e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 PB1 domain CDC24 PF06395.11 KIK45089.1 - 5.4e-12 45.8 0.1 1e-11 44.9 0.1 1.5 1 0 0 1 1 1 1 CDC24 Calponin PH PF00169.29 KIK45089.1 - 0.053 14.0 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 PH domain BRCT_2 PF16589.5 KIK45091.1 - 8.5e-09 35.7 0.0 2.4e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 KIK45091.1 - 1.2e-05 25.4 8.8 0.0024 18.0 0.9 3.3 3 0 0 3 3 3 2 Rap1 Myb domain BRCT PF00533.26 KIK45091.1 - 0.00046 20.5 0.0 0.00083 19.7 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rap1-DNA-bind PF09197.10 KIK45091.1 - 0.73 10.5 7.5 30 5.3 0.4 3.4 2 1 1 3 3 3 0 Rap1, DNA-binding PhyH PF05721.13 KIK45092.1 - 1.3e-46 159.6 0.0 1.5e-46 159.3 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) NolX PF05819.11 KIK45092.1 - 0.13 11.6 0.1 0.18 11.1 0.1 1.1 1 0 0 1 1 1 0 NolX protein HK PF02110.15 KIK45093.1 - 3.1e-77 259.3 1.3 1.6e-75 253.7 1.3 2.2 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KIK45093.1 - 1.2e-55 187.6 0.3 2.7e-55 186.5 0.3 1.6 1 0 0 1 1 1 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 KIK45093.1 - 0.00045 19.7 0.0 0.0021 17.5 0.0 2.0 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase REV1_C PF16727.5 KIK45093.1 - 0.18 12.2 0.1 0.37 11.2 0.1 1.5 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain p450 PF00067.22 KIK45094.1 - 2.3e-64 217.9 0.0 2.9e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MASE1 PF05231.14 KIK45095.1 - 2.2e-05 23.8 3.2 4.4e-05 22.8 3.2 1.4 1 0 0 1 1 1 1 MASE1 SUR7 PF06687.12 KIK45096.1 - 2.4e-10 40.4 16.3 1.8e-08 34.3 16.3 2.0 1 1 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.12 KIK45096.1 - 0.045 13.2 4.5 0.061 12.8 2.2 2.0 2 0 0 2 2 2 0 Clc-like DUF747 PF05346.11 KIK45098.1 - 5.9e-112 374.3 7.9 7.6e-112 373.9 7.9 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family Abhydrolase_9_N PF15420.6 KIK45098.1 - 0.22 11.5 3.5 0.25 11.3 1.9 1.9 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus F-box PF00646.33 KIK45099.1 - 5e-07 29.5 0.3 1.7e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIK45099.1 - 1.1e-05 25.2 0.5 0.00011 22.1 0.0 2.8 3 0 0 3 3 3 1 F-box-like F-box_4 PF15966.5 KIK45099.1 - 0.12 12.3 0.2 0.45 10.4 0.0 2.1 2 0 0 2 2 2 0 F-box WcbI PF18588.1 KIK45099.1 - 0.13 11.9 0.1 0.2 11.3 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis enzyme WcbI PRANC PF09372.10 KIK45099.1 - 0.14 12.5 0.1 0.99 9.8 0.0 2.3 2 0 0 2 2 2 0 PRANC domain OST-HTH PF12872.7 KIK45100.1 - 0.066 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 OST-HTH/LOTUS domain DUF2298 PF10060.9 KIK45101.1 - 0.028 13.2 4.3 0.038 12.7 4.3 1.1 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) Chromate_transp PF02417.15 KIK45106.1 - 3.5 7.7 6.7 10 6.2 0.3 2.1 1 1 1 2 2 2 0 Chromate transporter RrnaAD PF00398.20 KIK45108.1 - 2.4e-17 62.9 0.0 2.8e-16 59.4 0.0 2.0 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase HhH-GPD PF00730.25 KIK45109.1 - 5.1e-15 55.8 0.0 9.9e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Sec_GG PF07549.14 KIK45110.1 - 0.11 12.0 0.3 2.7 7.6 0.0 2.4 2 0 0 2 2 2 0 SecD/SecF GG Motif Oxidored_q6 PF01058.22 KIK45113.1 - 3.1e-22 78.8 0.2 5e-22 78.1 0.2 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit HET PF06985.11 KIK45114.1 - 1.2e-12 48.5 5.6 4.4e-10 40.1 0.6 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ARPC4 PF05856.12 KIK45115.1 - 2.2e-79 264.9 5.5 2.5e-79 264.7 5.5 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) GPS2_interact PF15784.5 KIK45115.1 - 0.013 15.9 1.6 1 9.9 0.1 2.2 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain FKBP_C PF00254.28 KIK45116.1 - 1.2e-30 105.6 0.0 3.1e-30 104.3 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KIK45116.1 - 3e-20 72.7 0.1 3e-20 72.7 0.1 2.3 2 1 0 2 2 2 1 Nucleoplasmin-like domain VIT_2 PF13757.6 KIK45116.1 - 0.14 12.0 0.0 0.36 10.8 0.0 1.6 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain Presenilin PF01080.17 KIK45116.1 - 1.2 7.8 9.4 1.8 7.2 9.4 1.2 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 KIK45116.1 - 2.5 5.1 7.0 3 4.8 7.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer WCOR413 PF05562.11 KIK45118.1 - 0.062 13.2 0.0 0.068 13.1 0.0 1.0 1 0 0 1 1 1 0 Cold acclimation protein WCOR413 Glyco_transf_34 PF05637.12 KIK45121.1 - 0.011 15.4 0.0 0.011 15.4 0.0 1.0 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family adh_short_C2 PF13561.6 KIK45124.1 - 1.7e-53 181.6 0.7 2e-53 181.3 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK45124.1 - 4.9e-40 137.1 0.5 6.8e-40 136.6 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK45124.1 - 3.1e-10 40.2 0.4 2e-09 37.6 0.4 1.9 1 1 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 KIK45124.1 - 0.018 15.7 0.0 0.07 13.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Cpn60_TCP1 PF00118.24 KIK45126.1 - 9.7e-163 542.3 0.2 1.3e-162 541.9 0.2 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AT_hook PF02178.19 KIK45127.1 - 0.0022 17.7 21.7 0.25 11.4 7.0 3.3 2 0 0 2 2 2 2 AT hook motif QH-AmDH_gamma PF08992.11 KIK45127.1 - 0.17 11.9 1.0 0.26 11.3 0.0 1.8 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, gamma subunit SET PF00856.28 KIK45129.1 - 6.1e-11 43.0 2.4 2.7e-10 40.9 0.4 2.5 2 1 0 2 2 2 1 SET domain PPP4R2 PF09184.11 KIK45129.1 - 1.2 8.7 6.4 1.8 8.1 6.4 1.2 1 0 0 1 1 1 0 PPP4R2 Ribosomal_S8e PF01201.22 KIK45130.1 - 8.2e-57 191.2 0.8 1.2e-56 190.7 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e UDPGP PF01704.18 KIK45132.1 - 5.4e-187 621.5 0.0 6.2e-187 621.3 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase UDPGP PF01704.18 KIK45133.1 - 5.3e-196 651.1 0.4 6.2e-196 650.9 0.4 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Metallophos PF00149.28 KIK45134.1 - 2.1e-07 31.7 0.1 3e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rpr2 PF04032.16 KIK45135.1 - 1.1e-22 80.1 3.0 1.6e-22 79.6 1.9 1.8 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-RING_7 PF02591.15 KIK45135.1 - 0.08 13.1 0.8 0.2 11.9 0.8 1.7 1 0 0 1 1 1 0 C4-type zinc ribbon domain DUF1178 PF06676.11 KIK45135.1 - 0.27 11.6 2.0 0.51 10.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) NADH_B2 PF14813.6 KIK45136.1 - 0.0085 15.9 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 CPSase_sm_chain PF00988.22 KIK45138.1 - 1.9e-44 150.5 0.0 3.2e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KIK45138.1 - 5.7e-37 127.3 0.0 8e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KIK45138.1 - 7.3e-08 32.4 0.2 3.5e-06 26.9 0.2 2.7 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KIK45138.1 - 0.0049 16.7 0.0 0.0078 16.0 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_M22 PF00814.25 KIK45138.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycoprotease family BSD PF03909.17 KIK45139.1 - 1.9e-11 43.8 0.2 6.1e-11 42.2 0.2 2.0 1 0 0 1 1 1 1 BSD domain DUF883 PF05957.13 KIK45139.1 - 0.016 15.8 5.6 0.61 10.7 0.1 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Metallophos PF00149.28 KIK45140.1 - 8.1e-08 33.0 0.0 1.5e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Scs3p PF10261.9 KIK45141.1 - 4.9e-40 137.6 10.0 2.7e-33 115.5 1.4 2.6 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 KIK45141.1 - 0.19 11.5 10.5 0.037 13.8 3.3 2.3 2 0 0 2 2 2 0 PAP2 superfamily HET PF06985.11 KIK45142.1 - 1.8e-11 44.6 5.6 4.3e-10 40.1 0.5 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_2 PF07719.17 KIK45142.1 - 8.2e-06 25.5 2.3 0.057 13.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK45142.1 - 1.9e-05 24.3 0.1 0.1 12.5 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK45142.1 - 0.00054 20.6 2.0 0.00054 20.6 2.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK45142.1 - 0.011 15.5 0.1 0.22 11.2 0.0 2.4 2 0 0 2 2 2 0 TPR repeat TPR_8 PF13181.6 KIK45142.1 - 0.022 15.0 0.3 6.4 7.3 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK45142.1 - 0.025 15.1 1.3 0.34 11.4 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Tsg PF04668.12 KIK45142.1 - 0.14 12.8 1.0 0.33 11.6 0.3 2.0 2 0 0 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region Retrotran_gag_2 PF14223.6 KIK45144.1 - 3.5e-11 42.9 0.2 5.3e-11 42.3 0.2 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Phenol_monoox PF04663.12 KIK45145.1 - 0.026 14.7 0.0 3.3 7.9 0.0 2.1 1 1 1 2 2 2 0 Phenol hydroxylase conserved region GATase_4 PF13230.6 KIK45146.1 - 0.012 14.5 0.0 0.058 12.3 0.0 1.9 2 0 0 2 2 2 0 Glutamine amidotransferases class-II KRAB PF01352.27 KIK45146.1 - 0.027 14.1 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 KRAB box RVP PF00077.20 KIK45146.1 - 0.038 14.3 0.1 0.26 11.6 0.1 2.3 2 1 0 2 2 2 0 Retroviral aspartyl protease Retrotran_gag_2 PF14223.6 KIK45147.1 - 4.8e-10 39.2 0.5 4.8e-10 39.2 0.5 1.4 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Myb_DNA-bind_2 PF08914.11 KIK45147.1 - 0.053 13.7 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Rap1 Myb domain Retrotran_gag_3 PF14244.6 KIK45147.1 - 0.088 12.6 0.0 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type PSP1 PF04468.12 KIK45148.1 - 0.036 14.4 1.0 0.23 11.7 0.4 2.3 2 1 0 2 2 2 0 PSP1 C-terminal conserved region Phage_holin_2_4 PF16082.5 KIK45148.1 - 9.9 6.0 7.0 26 4.6 7.0 1.7 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Phage_integrase PF00589.22 KIK45150.1 - 0.09 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family RVT_thumb PF06817.14 KIK45152.1 - 0.0022 17.8 0.0 0.0043 16.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase thumb domain Pkinase_fungal PF17667.1 KIK45155.1 - 0.0032 16.3 0.0 0.0037 16.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase DDE_Tnp_4 PF13359.6 KIK45156.1 - 5.7e-08 32.6 0.1 2.1e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease His_kinase PF06580.13 KIK45156.1 - 0.16 12.3 0.0 1.7 9.0 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase Retrotran_gag_2 PF14223.6 KIK45157.1 - 3.9e-08 33.1 0.5 1.1e-07 31.6 0.5 1.8 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type Abhydrolase_6 PF12697.7 KIK45157.1 - 0.029 15.0 0.0 0.054 14.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DASH_Dam1 PF08653.10 KIK45157.1 - 0.23 11.3 0.0 0.23 11.3 0.0 2.4 3 0 0 3 3 3 0 DASH complex subunit Dam1 Plavaka PF18759.1 KIK45160.1 - 7.7e-36 123.9 0.0 1.3e-35 123.2 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase GST_N PF02798.20 KIK45162.1 - 2.9e-14 53.1 0.1 6.1e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIK45162.1 - 6.4e-14 52.1 0.0 1.1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK45162.1 - 3.5e-13 49.6 0.0 5.3e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KIK45162.1 - 5.3e-09 36.3 0.0 1.2e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK45162.1 - 9.9e-05 22.3 0.0 0.00025 21.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK45162.1 - 0.00015 21.9 0.0 0.00029 21.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain motB PF17613.2 KIK45162.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Modifier of transcription DUF4112 PF13430.6 KIK45163.1 - 3.7e-34 117.1 0.1 4.9e-34 116.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Angiomotin_C PF12240.8 KIK45163.1 - 0.022 14.3 0.1 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 Angiomotin C terminal YbhQ PF11076.8 KIK45163.1 - 0.075 13.1 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ DHHC PF01529.20 KIK45165.1 - 8.8e-33 113.3 7.3 8.8e-33 113.3 7.3 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase TMEMspv1-c74-12 PF11044.8 KIK45165.1 - 2 8.5 4.2 33 4.6 1.6 2.4 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein MIS13 PF08202.11 KIK45166.1 - 1.4e-28 100.1 7.7 5.1e-28 98.2 7.7 1.8 1 1 0 1 1 1 1 Mis12-Mtw1 protein family Ala_racemase_N PF01168.20 KIK45167.1 - 4e-12 46.3 0.1 2.9e-11 43.4 0.1 2.1 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Peptidase_M54 PF07998.11 KIK45168.1 - 0.0076 16.3 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M54 HSP20 PF00011.21 KIK45169.1 - 0.00036 20.6 0.0 0.0008 19.5 0.0 1.6 1 1 0 1 1 1 1 Hsp20/alpha crystallin family WEMBL PF05701.11 KIK45171.1 - 0.00068 18.5 0.3 0.00073 18.4 0.3 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light ACT_6 PF13740.6 KIK45174.1 - 0.035 14.1 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 ACT domain ABC2_membrane PF01061.24 KIK45175.1 - 6.3e-35 120.5 20.8 6.3e-35 120.5 20.8 1.9 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.27 KIK45175.1 - 8.5e-28 97.6 0.1 1.6e-27 96.7 0.1 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIK45175.1 - 9.6e-05 22.3 0.0 0.55 10.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIK45175.1 - 0.0002 20.9 0.0 0.00033 20.2 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KIK45175.1 - 0.00026 20.9 0.0 0.00051 20.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 KIK45175.1 - 0.0004 19.6 23.3 0.0004 19.6 23.3 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 KIK45175.1 - 0.0015 18.2 0.1 0.0033 17.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain EGF_2 PF07974.13 KIK45175.1 - 0.003 17.9 13.1 0.003 17.9 13.1 3.5 3 0 0 3 3 2 1 EGF-like domain Rad17 PF03215.15 KIK45175.1 - 0.0086 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain MMR_HSR1 PF01926.23 KIK45175.1 - 0.034 14.2 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 KIK45175.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK45175.1 - 0.13 12.8 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zn-ribbon_8 PF09723.10 KIK45176.1 - 0.096 12.8 6.5 1.9 8.7 0.9 2.2 2 0 0 2 2 2 0 Zinc ribbon domain ADK_lid PF05191.14 KIK45176.1 - 5.4 7.1 9.7 11 6.1 1.4 2.2 1 1 1 2 2 2 0 Adenylate kinase, active site lid Pkinase PF00069.25 KIK45177.1 - 1.3e-49 169.0 0.0 1.3e-35 123.0 0.0 3.1 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK45177.1 - 1.8e-27 96.2 0.1 1.1e-20 74.0 0.1 3.3 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK45177.1 - 3.1e-05 22.9 0.0 6.4e-05 21.9 0.0 1.6 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK45177.1 - 9.9e-05 22.4 0.0 0.069 13.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK45177.1 - 0.0013 18.1 0.0 0.17 11.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Aminotran_1_2 PF00155.21 KIK45178.1 - 1.1e-26 93.9 0.0 1.3e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KIK45178.1 - 1.6e-09 37.1 0.0 2.3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase ISG65-75 PF11727.8 KIK45178.1 - 0.19 10.9 0.0 0.36 10.0 0.0 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein Baculo_PEP_C PF04513.12 KIK45179.1 - 0.0017 18.4 2.3 0.0047 17.0 2.3 1.8 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF724 PF05266.14 KIK45179.1 - 0.0017 18.2 9.9 0.0017 18.2 9.9 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF724) EzrA PF06160.12 KIK45179.1 - 0.0024 16.2 15.8 0.0024 16.2 15.8 2.1 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA MAD PF05557.13 KIK45179.1 - 0.19 10.1 32.1 0.28 9.5 32.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein ORF6C PF10552.9 KIK45179.1 - 0.45 10.6 12.8 0.49 10.5 5.3 2.8 1 1 0 2 2 2 0 ORF6C domain HIP1_clath_bdg PF16515.5 KIK45179.1 - 1.1 9.9 35.6 0.06 14.0 13.1 3.6 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Cob_adeno_trans PF01923.18 KIK45179.1 - 1.4 9.1 15.6 0.59 10.3 8.2 2.9 2 1 1 3 3 3 0 Cobalamin adenosyltransferase TolA_bind_tri PF16331.5 KIK45179.1 - 1.6 8.8 35.3 4.1 7.6 5.8 4.3 2 1 1 3 3 3 0 TolA binding protein trimerisation V_ATPase_I PF01496.19 KIK45179.1 - 1.9 6.3 22.2 0.17 9.7 9.0 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 KIK45179.1 - 2.1 8.4 14.0 0.11 12.5 4.6 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KIK45179.1 - 2.3 8.6 35.2 0.76 10.2 27.5 2.6 1 1 1 2 2 2 0 Fez1 PspA_IM30 PF04012.12 KIK45179.1 - 3.5 7.1 35.8 1.2 8.6 9.5 2.4 1 1 1 2 2 2 0 PspA/IM30 family GAS PF13851.6 KIK45179.1 - 4.3 6.6 37.0 0.054 12.9 13.1 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Spc24 PF08286.11 KIK45179.1 - 6.2 7.1 29.9 9.3 6.6 4.2 3.9 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.11 KIK45179.1 - 6.4 7.2 21.8 2.5 8.6 0.4 4.5 5 0 0 5 5 3 0 Flagella accessory protein C (FlaC) LMBR1 PF04791.16 KIK45179.1 - 9.9 4.9 11.6 17 4.2 11.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Ras PF00071.22 KIK45181.1 - 2.6e-45 154.0 0.1 2.9e-45 153.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK45181.1 - 8.7e-19 67.9 0.0 1.2e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK45181.1 - 4.1e-07 29.6 0.1 4.9e-07 29.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KIK45181.1 - 6.2e-05 23.0 1.0 0.039 13.9 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KIK45181.1 - 0.00014 21.4 0.1 0.0084 15.7 0.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.18 KIK45181.1 - 0.0003 20.2 0.3 0.24 10.7 0.1 2.3 2 1 0 2 2 2 2 Septin MMR_HSR1 PF01926.23 KIK45181.1 - 0.0011 19.1 0.1 0.0015 18.6 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KIK45181.1 - 0.03 14.6 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK45181.1 - 0.043 14.0 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 KIK45181.1 - 0.061 12.7 0.1 0.077 12.3 0.1 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AlkA_N PF06029.11 KIK45181.1 - 0.073 13.4 0.2 0.38 11.0 0.2 2.0 1 1 0 1 1 1 0 AlkA N-terminal domain Viral_helicase1 PF01443.18 KIK45181.1 - 0.079 12.7 0.0 0.22 11.2 0.0 1.7 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KIK45181.1 - 0.15 12.4 1.2 0.49 10.7 1.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain DEAD PF00270.29 KIK45182.1 - 3.3e-52 176.8 0.0 4.3e-51 173.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK45182.1 - 3.8e-32 110.9 0.0 1.4e-30 105.9 0.0 2.4 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK45182.1 - 3e-07 30.6 0.0 1.1e-06 28.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KIK45182.1 - 0.033 13.0 0.0 0.36 9.5 0.0 2.6 3 1 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF2313 PF10076.9 KIK45182.1 - 0.055 13.3 0.1 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2313) GRP PF07172.11 KIK45182.1 - 0.12 13.1 25.2 0.28 11.9 25.2 1.6 1 0 0 1 1 1 0 Glycine rich protein family tRNA-synt_1 PF00133.22 KIK45183.1 - 5.8e-215 715.1 0.0 8.6e-214 711.2 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KIK45183.1 - 1.2e-35 122.7 0.2 2.3e-35 121.8 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KIK45183.1 - 6.7e-14 51.4 0.1 2.3e-07 29.9 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KIK45183.1 - 3.2e-10 39.8 0.0 7e-08 32.2 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 KIK45183.1 - 0.0038 17.5 0.1 0.0038 17.5 0.1 3.0 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 KIK45183.1 - 0.066 12.5 0.0 1.8 7.9 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain ANAPC10 PF03256.16 KIK45184.1 - 3.9e-47 160.3 0.0 4.7e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 KIK45184.1 - 1e-05 25.6 0.0 2.4e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 F5/8 type C domain Actin PF00022.19 KIK45186.1 - 2.5e-47 161.4 0.0 1.8e-26 92.7 0.0 2.3 2 1 0 2 2 2 2 Actin ThiF PF00899.21 KIK45188.1 - 1.7e-63 214.2 0.0 3.3e-63 213.3 0.0 1.3 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KIK45188.1 - 1.6e-07 31.8 0.0 1.2e-06 29.0 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 KIK45188.1 - 0.0082 16.2 0.0 0.024 14.7 0.0 1.8 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KIK45188.1 - 0.062 13.6 0.2 0.16 12.2 0.2 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 KIK45188.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UBX PF00789.20 KIK45189.1 - 6.5e-12 45.5 0.3 1.1e-11 44.7 0.3 1.3 1 0 0 1 1 1 1 UBX domain PITH PF06201.13 KIK45190.1 - 4e-40 137.5 0.0 5e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain Presenilin PF01080.17 KIK45191.1 - 0.95 8.2 4.9 1.1 7.9 4.9 1.2 1 0 0 1 1 1 0 Presenilin TERB2 PF15101.6 KIK45191.1 - 8.8 6.3 13.0 0.25 11.3 4.4 2.0 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Med25_VWA PF11265.8 KIK45192.1 - 3.7e-07 30.2 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A YchF-GTPase_C PF06071.13 KIK45194.1 - 6.4e-35 119.2 0.0 2.4e-34 117.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KIK45194.1 - 2.4e-17 63.0 0.0 7.1e-17 61.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIK45194.1 - 1.9e-05 24.3 0.0 3.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B BetaGal_dom3 PF13363.6 KIK45194.1 - 0.13 11.8 0.0 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Beta-galactosidase, domain 3 SH3_1 PF00018.28 KIK45197.1 - 3.7e-08 32.8 0.1 6.2e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK45197.1 - 8.8e-08 31.9 0.1 1.4e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIK45197.1 - 1.1e-07 31.4 0.0 1.6e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Voldacs PF03517.13 KIK45199.1 - 2.2e-27 95.9 0.0 3.1e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Cu-oxidase PF00394.22 KIK45200.1 - 4.5e-43 147.1 0.5 5.5e-40 137.1 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK45200.1 - 2.6e-35 121.0 3.5 6.9e-35 119.6 0.2 2.9 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK45200.1 - 4.6e-34 117.1 11.0 3.7e-33 114.2 2.1 3.3 3 1 0 3 3 3 2 Multicopper oxidase MFS_1 PF07690.16 KIK45202.1 - 1.6e-17 63.5 27.6 1.5e-16 60.3 16.8 3.1 4 0 0 4 4 4 2 Major Facilitator Superfamily OATP PF03137.20 KIK45202.1 - 0.00061 18.2 0.5 0.0027 16.1 0.2 2.0 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family tRNA-synt_1g PF09334.11 KIK45204.1 - 3.8e-138 460.5 0.0 4.8e-138 460.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.20 KIK45204.1 - 3.7e-10 39.8 3.6 8.1e-10 38.7 3.6 1.6 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_1 PF00133.22 KIK45204.1 - 1.2e-05 23.8 0.0 0.0013 17.0 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KIK45204.1 - 0.0012 18.8 0.0 0.0027 17.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DUF1289 PF06945.13 KIK45204.1 - 0.61 9.9 5.1 8 6.4 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) DZR PF12773.7 KIK45204.1 - 1.4 9.0 5.3 3.5 7.7 5.3 1.7 1 1 0 1 1 1 0 Double zinc ribbon Bud13 PF09736.9 KIK45210.1 - 3.7e-55 186.3 11.9 3.7e-55 186.3 11.9 2.5 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex HSP20 PF00011.21 KIK45211.1 - 6.6e-09 35.8 0.0 1.1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIK45211.1 - 1.3e-06 27.9 0.1 3.1e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 HSP20-like domain found in ArsA UvrD-helicase PF00580.21 KIK45214.1 - 9.9e-65 219.1 0.0 1.8e-64 218.3 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KIK45214.1 - 9e-58 196.3 0.0 4.4e-57 194.0 0.0 2.1 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KIK45214.1 - 5.3e-29 101.4 0.0 1.2e-28 100.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KIK45214.1 - 4.2e-12 45.7 0.1 1.2e-11 44.3 0.1 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KIK45214.1 - 5e-07 29.7 0.4 0.16 11.6 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KIK45214.1 - 0.00044 20.0 0.1 0.25 11.0 0.0 2.6 3 0 0 3 3 3 2 AAA domain AAA_11 PF13086.6 KIK45214.1 - 0.009 15.8 0.5 0.027 14.2 0.5 1.9 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KIK45214.1 - 0.014 15.0 0.0 0.094 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain SOAR PF16533.5 KIK45214.1 - 0.065 13.2 0.3 0.21 11.6 0.1 1.9 2 0 0 2 2 2 0 STIM1 Orai1-activating region Aminotran_5 PF00266.19 KIK45215.1 - 1.5e-15 57.1 0.0 4.2e-14 52.3 0.0 2.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KIK45215.1 - 2.5e-07 30.4 0.9 1.7e-06 27.6 0.9 1.9 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KIK45215.1 - 1.2e-05 24.6 0.0 1.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DnaT PF17948.1 KIK45216.1 - 0.005 16.5 0.1 0.0064 16.2 0.1 1.1 1 0 0 1 1 1 1 DnaT DNA-binding domain DUF4586 PF15239.6 KIK45216.1 - 0.023 14.9 0.1 0.026 14.7 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4586) APC_u14 PF16635.5 KIK45216.1 - 0.068 13.7 0.4 0.08 13.5 0.4 1.2 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr GGACT PF06094.12 KIK45217.1 - 5.8e-14 52.7 0.0 8.7e-14 52.2 0.0 1.3 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF5539 PF17693.1 KIK45218.1 - 1.1 8.9 10.5 0.071 12.8 0.3 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5539) Metallophos PF00149.28 KIK45219.1 - 2.9e-07 31.2 0.6 6e-07 30.2 0.5 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIK45219.1 - 1.3e-05 25.4 0.0 2.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KIK45220.1 - 1.3e-10 42.2 0.0 3.8e-10 40.6 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIK45220.1 - 7.5e-07 29.5 0.0 1.4e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Peptidase_C14 PF00656.22 KIK45221.1 - 3.6e-64 217.1 0.0 4.3e-64 216.8 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Sugar_tr PF00083.24 KIK45223.1 - 2.9e-118 395.6 27.2 3.6e-118 395.3 27.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK45223.1 - 4.5e-25 88.3 53.7 2.1e-16 59.8 18.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase_fungal PF17667.1 KIK45224.1 - 1.1e-19 70.5 0.0 5.6e-19 68.2 0.0 1.8 1 1 1 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 KIK45224.1 - 0.0001 21.8 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK45224.1 - 0.057 13.3 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family CTU2 PF10288.9 KIK45225.1 - 2.7e-17 63.0 0.1 6.5e-17 61.8 0.1 1.6 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 zf-C3HC4_3 PF13920.6 KIK45225.1 - 5.9 6.8 16.0 0.06 13.2 0.9 4.0 5 0 0 5 5 5 0 Zinc finger, C3HC4 type (RING finger) UPRTase PF14681.6 KIK45226.1 - 3.8e-49 166.9 0.8 7.3e-47 159.5 0.0 2.5 3 0 0 3 3 3 2 Uracil phosphoribosyltransferase PRK PF00485.18 KIK45226.1 - 5.8e-46 156.7 0.0 8.9e-46 156.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KIK45226.1 - 1.9e-05 25.2 0.0 4.1e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIK45226.1 - 4.8e-05 23.6 0.0 0.00022 21.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KIK45226.1 - 0.00057 19.2 0.0 0.0014 18.0 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 KIK45226.1 - 0.0016 18.9 0.0 0.76 10.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain CoaE PF01121.20 KIK45226.1 - 0.071 12.8 0.2 0.96 9.1 0.1 2.3 2 0 0 2 2 2 0 Dephospho-CoA kinase JmjN PF02375.17 KIK45227.1 - 0.086 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 jmjN domain WD40 PF00400.32 KIK45230.1 - 9.7e-33 111.7 8.2 8.8e-08 32.7 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat HET PF06985.11 KIK45230.1 - 7.3e-11 42.6 2.8 6.9e-10 39.5 0.3 2.5 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) TPR_1 PF00515.28 KIK45230.1 - 1.5e-08 34.1 3.2 1.3 9.0 0.0 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 KIK45230.1 - 1.3e-07 31.8 0.3 10 6.5 0.0 5.5 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 KIK45230.1 - 5.2e-07 29.3 12.8 14 6.1 0.1 8.2 9 0 0 9 9 9 0 Tetratricopeptide repeat eIF2A PF08662.11 KIK45230.1 - 0.00016 21.6 0.1 0.037 13.9 0.0 3.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A TPR_11 PF13414.6 KIK45230.1 - 0.00079 19.1 1.2 0.096 12.4 0.0 3.9 4 0 0 4 4 4 1 TPR repeat TPR_14 PF13428.6 KIK45230.1 - 0.0026 18.5 5.4 8.1 7.6 0.0 5.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIK45230.1 - 0.0056 17.0 0.1 12 6.5 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK45230.1 - 0.011 15.6 0.5 3.3 8.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK45230.1 - 0.014 15.9 7.9 10 6.7 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF713 PF05218.14 KIK45230.1 - 0.035 13.8 0.1 0.067 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF713) TPR_16 PF13432.6 KIK45230.1 - 0.16 12.6 12.7 6.3 7.5 0.1 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK45230.1 - 0.5 10.7 5.2 48 4.5 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.32 KIK45231.1 - 9.5e-35 118.0 7.9 1.2e-07 32.3 0.0 7.8 7 0 0 7 7 7 5 WD domain, G-beta repeat HET PF06985.11 KIK45231.1 - 3.4e-09 37.2 4.0 5.2e-06 26.9 0.3 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ANAPC4_WD40 PF12894.7 KIK45231.1 - 1.6e-08 34.7 1.3 4.9 7.5 0.0 6.7 2 1 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK45231.1 - 0.088 12.8 6.9 78 3.4 0.1 5.6 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Na_Ca_ex PF01699.24 KIK45233.1 - 6.3e-27 94.4 26.5 4.5e-14 52.7 11.9 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein COX5B PF01215.19 KIK45234.1 - 3e-47 159.5 0.0 3.6e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 KIK45234.1 - 0.0069 16.4 0.2 0.01 15.9 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger domain TF_Zn_Ribbon PF08271.12 KIK45234.1 - 0.084 12.4 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding APH PF01636.23 KIK45235.1 - 5.7e-11 42.8 0.0 9.6e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family ABC2_membrane_5 PF13346.6 KIK45236.1 - 5.2 6.6 12.3 7.9 6.0 12.3 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein F-box-like PF12937.7 KIK45237.1 - 1.9e-07 30.8 1.7 3.3e-07 30.1 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK45237.1 - 2e-06 27.5 0.9 5.5e-06 26.1 0.4 1.9 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KIK45237.1 - 0.08 12.8 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 F-box zf-C2H2 PF00096.26 KIK45238.1 - 2.4e-07 30.8 7.7 4.8e-05 23.6 0.6 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK45238.1 - 2.7e-07 30.7 5.0 1.8e-05 24.9 0.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK45238.1 - 3.3e-07 30.6 5.4 0.00025 21.6 0.6 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KIK45238.1 - 9.7e-05 22.0 0.2 9.7e-05 22.0 0.2 1.9 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-met PF12874.7 KIK45238.1 - 0.0016 18.8 5.3 0.068 13.6 0.4 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KIK45238.1 - 0.09 12.7 2.3 4 7.4 0.8 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 KIK45238.1 - 0.22 11.8 2.9 2.6 8.5 0.2 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Torus PF16131.5 KIK45241.1 - 1.1e-39 135.4 2.6 1.7e-39 134.9 2.6 1.3 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 KIK45241.1 - 2.9e-05 23.8 0.0 5.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KIK45241.1 - 0.00022 21.2 0.0 0.00046 20.1 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Peptidase_M35 PF02102.15 KIK45241.1 - 0.12 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family zf_CCCH_4 PF18345.1 KIK45241.1 - 0.16 12.1 5.9 0.3 11.2 5.9 1.5 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_4 PF18044.1 KIK45241.1 - 0.79 9.6 8.6 1.4 8.8 8.6 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger ANAPC4_WD40 PF12894.7 KIK45242.1 - 0.00031 21.0 0.0 0.02 15.2 0.0 3.1 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2415 PF10313.9 KIK45242.1 - 0.02 14.8 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 KIK45242.1 - 0.021 15.7 5.4 63 4.7 0.2 5.4 4 1 1 5 5 5 0 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KIK45242.1 - 0.12 11.4 0.0 0.24 10.3 0.0 1.5 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Sugar_tr PF00083.24 KIK45244.1 - 1.1e-52 179.4 27.0 1.4e-52 179.1 27.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK45244.1 - 1.5e-19 70.2 28.7 1.5e-19 70.2 28.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_membrane PF00664.23 KIK45245.1 - 2e-38 132.6 10.1 2.6e-38 132.3 10.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KIK45245.1 - 4.6e-34 117.9 0.0 9.5e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIK45245.1 - 3.9e-06 26.5 0.3 0.0013 18.2 0.0 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIK45245.1 - 9.4e-05 22.4 0.0 0.063 13.1 0.0 2.6 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIK45245.1 - 0.00089 19.1 0.0 0.0057 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 KIK45245.1 - 0.0036 17.7 0.0 0.011 16.1 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK45245.1 - 0.0086 16.5 0.0 0.11 13.0 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK45245.1 - 0.013 15.8 0.1 0.051 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain RuvX PF03652.15 KIK45245.1 - 0.026 14.9 0.0 0.058 13.8 0.0 1.6 1 0 0 1 1 1 0 Holliday junction resolvase Rad17 PF03215.15 KIK45245.1 - 0.03 14.3 0.0 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 KIK45245.1 - 0.038 13.7 0.0 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KIK45245.1 - 0.043 14.3 0.0 0.22 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KIK45245.1 - 0.049 13.7 0.2 0.36 10.9 0.0 2.5 4 0 0 4 4 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KIK45245.1 - 0.067 13.7 0.0 0.24 12.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain G-alpha PF00503.20 KIK45245.1 - 0.07 12.3 0.1 0.13 11.4 0.0 1.5 2 0 0 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.14 KIK45245.1 - 0.076 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KIK45245.1 - 0.11 12.7 0.0 0.54 10.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KIK45245.1 - 0.11 12.5 0.0 0.58 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KIK45245.1 - 0.53 10.0 2.9 21 4.8 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein Borrelia_P13 PF05628.12 KIK45245.1 - 0.61 10.0 2.7 1.9 8.4 0.1 2.6 2 1 1 3 3 3 0 Borrelia membrane protein P13 Metallophos PF00149.28 KIK45246.1 - 1.1e-14 55.4 0.2 1.8e-14 54.7 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIK45246.1 - 0.00015 22.0 0.1 0.0018 18.5 0.0 2.3 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain WD40 PF00400.32 KIK45249.1 - 1.7e-42 142.5 27.4 9.6e-07 29.4 0.1 8.7 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45249.1 - 6.7e-18 64.8 4.2 0.0058 16.9 0.2 6.9 2 1 6 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 KIK45249.1 - 8.2e-11 42.5 5.8 1.2e-09 38.6 0.8 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ge1_WD40 PF16529.5 KIK45249.1 - 4.8e-06 25.8 3.9 0.61 9.0 0.0 5.4 3 2 4 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK45249.1 - 0.00011 22.1 0.7 12 5.9 0.0 5.2 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK45249.1 - 0.00035 19.0 0.1 2.5 6.3 0.0 3.4 2 1 2 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz DUF4784 PF16023.5 KIK45249.1 - 0.031 13.2 0.0 0.12 11.3 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4784) TPR_1 PF00515.28 KIK45249.1 - 0.065 13.1 0.3 0.4 10.6 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat MFS_1 PF07690.16 KIK45252.1 - 1.1e-33 116.7 67.7 8.2e-33 113.8 67.7 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily LRR_8 PF13855.6 KIK45253.1 - 2.5e-21 75.2 22.1 1.2e-08 34.5 0.8 8.6 7 3 2 9 9 9 5 Leucine rich repeat LRR_4 PF12799.7 KIK45253.1 - 1.2e-18 66.9 22.5 2.4e-05 24.6 5.3 8.6 8 1 0 9 9 9 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KIK45253.1 - 1.4e-08 34.1 18.5 0.43 11.3 0.1 9.3 10 0 0 10 10 10 4 Leucine Rich Repeat LRR_6 PF13516.6 KIK45253.1 - 3.8e-07 29.6 15.1 0.81 9.9 0.0 7.6 7 0 0 7 7 7 3 Leucine Rich repeat LRR_9 PF14580.6 KIK45253.1 - 0.0037 16.8 0.2 0.033 13.7 0.0 2.7 3 0 0 3 3 3 1 Leucine-rich repeat LRR_5 PF13306.6 KIK45253.1 - 0.14 12.2 0.4 0.85 9.6 0.1 2.1 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) DFRP_C PF16543.5 KIK45254.1 - 6.8e-26 90.6 2.0 6.8e-26 90.6 2.0 3.7 2 1 1 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH_4 PF18044.1 KIK45254.1 - 1.5e-06 27.8 8.2 8.4e-05 22.3 1.7 3.2 3 0 0 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 KIK45254.1 - 3.2e-06 27.8 15.3 0.00048 20.8 5.2 3.6 2 1 1 3 3 3 2 Torus domain zf-CCCH PF00642.24 KIK45254.1 - 3.8e-05 23.5 0.9 3.8e-05 23.5 0.9 2.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIK45254.1 - 6.1e-05 22.9 6.6 6.1e-05 22.9 6.6 3.2 3 1 0 3 3 3 1 Zinc finger domain Alpha-mann_mid PF09261.11 KIK45254.1 - 0.016 15.4 0.4 0.042 14.0 0.4 1.7 1 0 0 1 1 1 0 Alpha mannosidase middle domain zf-CCCH_2 PF14608.6 KIK45254.1 - 0.19 12.2 10.5 0.7 10.4 3.9 2.8 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger ESM4 PF15952.5 KIK45258.1 - 0.071 13.5 1.1 0.13 12.7 1.1 1.4 1 0 0 1 1 1 0 Enhancer of split M4 family Eapp_C PF10238.9 KIK45258.1 - 0.53 10.4 7.5 0.26 11.3 3.6 2.4 2 1 0 2 2 2 0 E2F-associated phosphoprotein Death PF00531.22 KIK45259.1 - 0.042 14.0 0.1 0.049 13.8 0.1 1.2 1 0 0 1 1 1 0 Death domain Plavaka PF18759.1 KIK45260.1 - 3.9e-65 220.2 5.9 4.2e-64 216.8 0.0 2.1 1 1 1 2 2 2 2 Plavaka transposase Pkinase_fungal PF17667.1 KIK45262.1 - 1.2e-12 47.3 0.0 1.3e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase zf-CCHC PF00098.23 KIK45265.1 - 2.4 8.4 13.6 2.4 8.4 0.3 3.9 3 1 0 3 3 3 0 Zinc knuckle zf-CCHC_5 PF14787.6 KIK45265.1 - 2.7 7.8 7.8 4.2 7.2 3.4 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger OrfB_Zn_ribbon PF07282.11 KIK45265.1 - 3.7 7.5 8.3 0.42 10.6 3.0 2.0 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DUF5446 PF17522.2 KIK45266.1 - 0.21 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5446) RVT_1 PF00078.27 KIK45268.1 - 1.2e-08 34.8 0.0 1.4e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 KIK45270.1 - 1.4e-06 28.9 0.2 2.4e-06 28.2 0.2 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Pkinase_fungal PF17667.1 KIK45271.1 - 0.16 10.7 0.0 0.29 9.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Nop14 PF04147.12 KIK45272.1 - 0.095 10.9 18.7 1.1 7.4 17.3 2.1 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.14 KIK45272.1 - 3.4 5.9 18.4 5.8 5.1 18.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Mito_carr PF00153.27 KIK45273.1 - 7.7e-46 154.0 4.5 6e-19 67.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Acyl-CoA_dh_1 PF00441.24 KIK45274.1 - 5.2e-45 153.3 2.0 7.3e-45 152.8 2.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KIK45274.1 - 2.2e-26 92.7 0.2 1.5e-25 90.0 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KIK45274.1 - 3.2e-23 81.8 0.0 6.9e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KIK45274.1 - 1.1e-21 77.5 0.2 1.6e-21 77.0 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 KIK45274.1 - 0.0073 16.9 0.0 0.015 15.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal DUF2433 PF10360.9 KIK45275.1 - 7.9e-44 148.7 0.3 3.6e-43 146.6 0.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_1 PF00076.22 KIK45275.1 - 0.0043 16.9 0.1 0.0078 16.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 KIK45275.1 - 0.046 14.2 0.0 0.08 13.4 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase SWI-SNF_Ssr4 PF08549.10 KIK45275.1 - 0.075 11.7 7.4 0.1 11.2 7.4 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Med13_N PF11597.8 KIK45276.1 - 7e-42 143.9 4.8 2e-41 142.4 4.8 1.8 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal Med13_C PF06333.12 KIK45276.1 - 1.2e-40 139.8 4.0 1.2e-40 139.8 4.0 3.6 2 2 1 3 3 3 1 Mediator complex subunit 13 C-terminal domain ATP-synt_S1 PF05827.12 KIK45277.1 - 0.033 14.0 0.1 0.06 13.2 0.1 1.3 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Spt4 PF06093.13 KIK45278.1 - 1.8e-29 101.7 0.2 2.1e-29 101.4 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Lipase_3 PF01764.25 KIK45279.1 - 1.7e-14 53.9 0.0 3.5e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIK45279.1 - 0.046 14.3 0.5 0.13 12.8 0.1 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK45279.1 - 0.076 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_M24 PF00557.24 KIK45280.1 - 2.3e-57 194.1 0.0 3e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KIK45280.1 - 1.5e-36 124.9 0.0 2.8e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain AA_permease_2 PF13520.6 KIK45281.1 - 4.8e-43 147.6 46.0 5.6e-43 147.4 46.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK45281.1 - 3.3e-18 65.5 37.5 4.2e-18 65.2 37.5 1.1 1 0 0 1 1 1 1 Amino acid permease GTP_EFTU PF00009.27 KIK45282.1 - 7.8e-32 110.4 2.1 1.5e-31 109.5 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KIK45282.1 - 1.7e-19 69.9 0.0 5e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KIK45282.1 - 1.2e-14 54.4 5.3 9.5e-10 38.7 0.1 3.3 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIK45282.1 - 3.2e-07 30.4 0.3 6.5e-06 26.2 0.0 3.0 3 0 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KIK45282.1 - 3.5e-05 23.6 0.0 0.00015 21.5 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Roc PF08477.13 KIK45282.1 - 7.5e-05 22.9 0.0 0.00019 21.6 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KIK45282.1 - 0.0004 20.2 0.1 0.0022 17.8 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Ras PF00071.22 KIK45282.1 - 0.0024 17.5 0.0 0.0098 15.5 0.0 2.1 1 1 0 1 1 1 1 Ras family MAP7 PF05672.11 KIK45282.1 - 0.0077 15.9 32.3 0.0077 15.9 32.3 2.1 3 0 0 3 3 3 1 MAP7 (E-MAP-115) family AAA_22 PF13401.6 KIK45282.1 - 0.029 14.6 0.3 0.31 11.3 0.3 2.4 1 1 0 1 1 1 0 AAA domain MCD PF05292.11 KIK45282.1 - 0.74 9.3 5.7 1.7 8.1 5.7 1.5 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain Arf PF00025.21 KIK45285.1 - 7.2e-68 227.5 0.1 8.2e-68 227.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KIK45285.1 - 1.7e-13 50.5 1.6 9e-08 31.7 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KIK45285.1 - 2.5e-11 43.8 0.0 3.6e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KIK45285.1 - 3.5e-09 36.3 0.0 4.9e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KIK45285.1 - 5.4e-09 35.7 0.0 6.9e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KIK45285.1 - 1.5e-08 34.4 0.0 1.8e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KIK45285.1 - 2.7e-07 30.7 0.0 9.8e-07 28.9 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KIK45285.1 - 0.041 13.6 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 KIK45285.1 - 0.08 12.5 0.1 0.42 10.1 0.1 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B DUF2025 PF09634.10 KIK45285.1 - 0.14 12.2 0.1 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2025) Dynamin_N PF00350.23 KIK45285.1 - 0.16 12.0 0.0 2.4 8.2 0.1 2.5 2 1 0 3 3 3 0 Dynamin family CMAS PF02353.20 KIK45286.1 - 8.7e-57 192.5 0.0 1.1e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KIK45286.1 - 5.1e-09 36.7 0.0 1.3e-08 35.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK45286.1 - 1.4e-07 32.1 0.0 2.9e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK45286.1 - 4.3e-05 23.4 0.0 6.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK45286.1 - 0.0055 17.4 0.0 0.012 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK45286.1 - 0.037 13.8 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SAC3 PF12209.8 KIK45286.1 - 0.051 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Leucine permease transcriptional regulator helical domain Methyltransf_24 PF13578.6 KIK45286.1 - 0.13 13.3 0.1 0.98 10.5 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain Kinesin PF00225.23 KIK45287.1 - 9.1e-108 360.1 0.0 1.5e-107 359.4 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 KIK45287.1 - 1.6e-43 149.0 0.0 5.1e-43 147.4 0.0 2.0 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 KIK45287.1 - 1.5e-38 132.8 6.7 3.1e-30 105.6 2.5 2.8 1 1 1 2 2 2 2 Kinesin-associated Microtub_bd PF16796.5 KIK45287.1 - 1.7e-21 76.8 0.0 3.8e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 KIK45287.1 - 4.7e-09 36.7 0.0 1.5e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 PH domain KIF1B PF12423.8 KIK45287.1 - 2.1e-07 31.3 0.2 9.7e-07 29.1 0.2 2.2 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.26 KIK45287.1 - 1.4e-06 28.6 0.0 6.3e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 FHA domain PilJ PF13675.6 KIK45287.1 - 2.8 8.0 5.2 45 4.1 0.2 3.1 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term EAP30 PF04157.16 KIK45287.1 - 4.6 6.5 6.5 0.32 10.3 0.5 2.2 2 0 0 2 2 2 0 EAP30/Vps36 family S4 PF01479.25 KIK45288.1 - 1.6e-11 43.7 0.0 2.9e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KIK45288.1 - 2.1e-09 38.2 0.5 3.1e-09 37.6 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Herpes_LAMP2 PF06126.11 KIK45288.1 - 0.067 11.8 0.0 0.077 11.6 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 LIM_bind PF01803.16 KIK45289.1 - 6.4e-64 215.8 0.0 6.4e-64 215.8 0.0 3.4 2 1 1 3 3 3 1 LIM-domain binding protein DUF702 PF05142.12 KIK45289.1 - 0.47 10.9 9.6 1.5 9.2 9.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF702) TERB2 PF15101.6 KIK45289.1 - 0.59 10.1 12.5 1.3 9.1 12.5 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DivIC PF04977.15 KIK45289.1 - 4.8 7.0 16.5 9.9 6.0 16.5 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4407 PF14362.6 KIK45289.1 - 6.1 6.1 10.1 9.7 5.4 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med26 PF08711.11 KIK45290.1 - 6.5e-09 35.7 0.2 1.3e-08 34.7 0.2 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-CCCH_4 PF18044.1 KIK45290.1 - 2.8e-07 30.2 3.0 4.2e-07 29.6 3.0 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KIK45290.1 - 1.5e-06 28.0 4.4 2.7e-06 27.1 4.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIK45290.1 - 4.2e-06 26.6 4.4 7.1e-06 25.9 4.4 1.4 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KIK45290.1 - 0.00097 19.8 0.5 0.0029 18.3 0.5 1.8 1 0 0 1 1 1 1 Torus domain Spectrin PF00435.21 KIK45290.1 - 0.11 13.0 0.6 17 5.9 0.1 2.5 2 0 0 2 2 2 0 Spectrin repeat zf-CCCH_2 PF14608.6 KIK45290.1 - 0.4 11.2 2.8 0.78 10.3 2.8 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger HMG_box PF00505.19 KIK45291.1 - 3.5e-17 62.6 0.5 8.5e-17 61.3 0.5 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK45291.1 - 2.5e-08 34.4 0.3 2.5e-08 34.4 0.3 2.2 2 0 0 2 2 2 1 HMG-box domain Protamine_like PF06382.11 KIK45291.1 - 0.0034 17.6 0.6 0.0034 17.6 0.6 1.8 1 1 1 2 2 2 1 Protamine and protamine like FAM195 PF14799.6 KIK45291.1 - 0.14 12.5 1.9 0.86 10.0 0.0 2.3 1 1 1 2 2 2 0 FAM195 family ATPase PF06745.13 KIK45291.1 - 0.37 10.1 1.7 0.36 10.2 0.1 1.6 2 0 0 2 2 2 0 KaiC SAPS PF04499.15 KIK45291.1 - 2.5 6.8 8.1 2.9 6.6 8.1 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein WW PF00397.26 KIK45292.1 - 0.0002 21.4 4.0 0.00038 20.5 4.0 1.5 1 0 0 1 1 1 1 WW domain CYSTM PF12734.7 KIK45292.1 - 0.023 15.0 3.2 0.023 15.0 3.2 3.5 3 1 0 3 3 3 0 Cysteine-rich TM module stress tolerance COesterase PF00135.28 KIK45295.1 - 1.9e-82 277.8 0.3 4e-82 276.7 0.3 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK45295.1 - 2.4e-08 34.1 0.8 3e-07 30.5 0.8 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK45295.1 - 0.0021 17.6 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PNP_UDP_1 PF01048.20 KIK45295.1 - 0.1 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphorylase superfamily Esterase PF00756.20 KIK45295.1 - 0.11 12.1 0.2 3.1 7.4 0.0 2.2 2 0 0 2 2 2 0 Putative esterase Say1_Mug180 PF10340.9 KIK45295.1 - 0.19 10.6 0.0 17 4.1 0.0 2.2 2 0 0 2 2 2 0 Steryl acetyl hydrolase SNF2_N PF00176.23 KIK45296.1 - 2.3e-55 187.8 0.1 6.6e-54 182.9 0.1 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK45296.1 - 4.6e-14 52.7 0.0 1e-13 51.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 KIK45296.1 - 1.8e-05 25.0 3.6 1.8e-05 25.0 3.6 2.6 2 0 0 2 2 2 1 Ring finger domain ResIII PF04851.15 KIK45296.1 - 1.9e-05 24.8 0.0 3.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KIK45296.1 - 2.4e-05 24.1 2.7 2.4e-05 24.1 2.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK45296.1 - 0.00056 19.7 3.9 0.00056 19.7 3.9 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK45296.1 - 0.00074 19.3 3.2 0.00074 19.3 3.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIK45296.1 - 0.0013 19.0 1.7 0.0033 17.7 1.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KIK45296.1 - 0.0035 17.2 3.1 0.0035 17.2 3.1 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KIK45296.1 - 0.013 15.3 2.0 0.032 14.0 2.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Ribosomal_L2_C PF03947.18 KIK45298.1 - 8.7e-46 155.2 4.1 8.7e-46 155.2 4.1 1.7 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KIK45298.1 - 7.1e-18 64.3 0.1 1.7e-17 63.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SH3_1 PF00018.28 KIK45300.1 - 3.4e-13 49.0 0.1 5.2e-13 48.4 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK45300.1 - 9.9e-11 41.3 0.1 1.6e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIK45300.1 - 6.8e-07 28.9 0.0 1.2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Cyclin_N PF00134.23 KIK45301.1 - 7.6e-14 51.6 0.0 1.2e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIK45301.1 - 1.3e-08 35.4 0.0 2.7e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Cyclin UAA PF08449.11 KIK45302.1 - 4.8e-81 272.3 7.0 2.3e-80 270.0 7.0 1.8 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KIK45302.1 - 0.0019 17.5 0.6 0.0038 16.4 0.6 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter SLC35F PF06027.12 KIK45302.1 - 0.0063 16.1 3.7 0.0069 15.9 1.1 2.3 2 0 0 2 2 2 1 Solute carrier family 35 CRT-like PF08627.10 KIK45302.1 - 0.022 13.7 0.5 0.022 13.7 0.5 2.3 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KIK45302.1 - 0.023 14.8 25.5 0.057 13.6 3.1 3.3 3 1 0 3 3 3 0 EamA-like transporter family PUNUT PF16913.5 KIK45302.1 - 0.13 11.4 15.3 0.037 13.2 0.9 2.6 3 0 0 3 3 3 0 Purine nucleobase transmembrane transport Cwf_Cwc_15 PF04889.12 KIK45303.1 - 1.3e-83 280.5 22.4 1.5e-83 280.4 22.4 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 KIK45303.1 - 0.0045 16.5 21.1 0.0051 16.3 21.1 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 KIK45303.1 - 0.0064 14.8 23.8 0.0075 14.6 23.8 1.1 1 0 0 1 1 1 1 Nop14-like family RR_TM4-6 PF06459.12 KIK45303.1 - 0.05 13.4 18.4 0.066 13.0 18.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KIK45303.1 - 0.18 10.0 18.1 0.23 9.7 18.1 1.2 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 KIK45303.1 - 1.2 7.9 5.2 1.4 7.6 5.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PA26 PF04636.13 KIK45303.1 - 2.4 7.0 5.8 2.6 6.9 5.8 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF3381 PF11861.8 KIK45303.1 - 2.5 7.9 27.7 0.47 10.2 22.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) RRN3 PF05327.11 KIK45303.1 - 4.3 5.8 12.8 5 5.5 12.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF913 PF06025.12 KIK45303.1 - 4.4 6.2 6.6 5.5 5.9 6.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 KIK45303.1 - 6.5 5.4 10.5 7.7 5.2 10.5 1.2 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 KIK45303.1 - 8.7 5.6 14.7 13 5.0 14.7 1.3 1 0 0 1 1 1 0 NOA36 protein Paf1 PF03985.13 KIK45303.1 - 9.8 5.0 22.4 15 4.4 22.4 1.5 1 0 0 1 1 1 0 Paf1 MIF4G_like_2 PF09090.11 KIK45304.1 - 1.3e-73 247.8 0.0 1.9e-73 247.3 0.0 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 KIK45304.1 - 4.4e-65 219.0 0.0 1.2e-64 217.6 0.0 1.8 2 0 0 2 2 2 1 MIF4G like MIF4G PF02854.19 KIK45304.1 - 0.16 11.6 0.0 0.53 9.9 0.0 1.8 2 0 0 2 2 2 0 MIF4G domain PPR_2 PF13041.6 KIK45305.1 - 4.1e-06 26.9 0.1 0.0002 21.4 0.0 3.7 5 0 0 5 5 5 1 PPR repeat family PPR_3 PF13812.6 KIK45305.1 - 0.0014 18.6 0.0 0.03 14.4 0.0 3.2 4 0 0 4 4 4 1 Pentatricopeptide repeat domain mIF3 PF14877.6 KIK45306.1 - 2.5e-08 33.8 0.3 1.7e-05 24.5 0.3 2.1 1 1 0 1 1 1 1 Mitochondrial translation initiation factor IF3_C PF00707.22 KIK45306.1 - 1.7e-05 24.7 0.0 3.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 KIK45306.1 - 0.00047 20.4 0.1 0.00091 19.4 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain Mito_carr PF00153.27 KIK45308.1 - 2.1e-64 213.5 1.9 1e-23 83.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Acyl-CoA_dh_1 PF00441.24 KIK45310.1 - 4e-29 101.8 0.6 5.7e-29 101.3 0.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIK45310.1 - 3.2e-14 52.9 0.5 6.1e-14 52.0 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KIK45310.1 - 7.5e-14 52.4 0.0 2.7e-13 50.6 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 KIK45310.1 - 1.6e-13 50.6 0.0 1e-12 48.0 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 KIK45310.1 - 1.8e-05 25.0 0.4 3.2e-05 24.2 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Vault PF01505.18 KIK45310.1 - 0.13 12.4 0.1 11 6.3 0.0 3.2 3 0 0 3 3 3 0 Major Vault Protein repeat domain Cyclin PF08613.11 KIK45311.1 - 8.3e-41 140.0 5.3 3e-40 138.2 5.3 2.0 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KIK45311.1 - 0.17 11.6 0.1 0.67 9.7 0.1 1.8 1 1 1 2 2 2 0 Cyclin, N-terminal domain Plavaka PF18759.1 KIK45316.1 - 3.8e-14 52.7 0.1 4.9e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase F-box-like PF12937.7 KIK45318.1 - 0.031 14.2 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 F-box-like DUF1157 PF06636.11 KIK45319.1 - 0.091 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1157) FtsK_4TM PF13491.6 KIK45319.1 - 0.29 10.8 5.3 1 9.0 5.4 1.8 1 1 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE Mito_fiss_reg PF05308.11 KIK45320.1 - 1.3 9.0 4.8 0.26 11.4 1.3 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator GSHPx PF00255.19 KIK45322.1 - 2.5e-42 142.8 0.1 3.2e-42 142.5 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KIK45322.1 - 6.8e-05 22.8 0.1 0.00026 20.9 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIK45322.1 - 0.00074 19.3 0.1 0.0064 16.2 0.1 2.1 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.6 KIK45322.1 - 0.068 13.7 0.0 0.24 11.9 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) DUF2624 PF11116.8 KIK45323.1 - 0.092 13.6 0.3 1.8 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) Rtf2 PF04641.12 KIK45323.1 - 0.94 8.8 8.6 1.4 8.3 8.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger SAPS PF04499.15 KIK45323.1 - 1.3 7.7 5.0 1.3 7.7 5.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 KIK45323.1 - 1.4 7.1 9.8 1.9 6.7 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RPN2_C PF18004.1 KIK45323.1 - 4.9 7.1 10.6 7.3 6.5 10.6 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Presenilin PF01080.17 KIK45323.1 - 8.8 5.0 5.2 11 4.7 5.2 1.1 1 0 0 1 1 1 0 Presenilin zf-Sec23_Sec24 PF04810.15 KIK45325.1 - 0.025 14.6 0.3 0.049 13.7 0.1 1.6 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger HMG_box PF00505.19 KIK45330.1 - 0.21 12.0 0.7 38 4.8 0.0 3.2 2 1 2 4 4 4 0 HMG (high mobility group) box Thx PF17070.5 KIK45330.1 - 4 7.7 7.5 77 3.6 0.2 3.3 3 0 0 3 3 3 0 30S ribosomal protein Thx Adeno_E3 PF06040.11 KIK45332.1 - 0.2 11.8 0.1 0.74 10.0 0.0 1.9 2 0 0 2 2 2 0 Adenovirus E3 protein Metallophos PF00149.28 KIK45333.1 - 1.1e-12 48.9 0.0 2.3e-12 47.9 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 KIK45333.1 - 0.005 15.2 0.1 0.019 13.3 0.0 1.8 2 0 0 2 2 2 1 Firmicute fructose-1,6-bisphosphatase AAA PF00004.29 KIK45338.1 - 2.9e-41 141.0 0.0 4.9e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KIK45338.1 - 1.3e-10 41.1 0.1 2.4e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KIK45338.1 - 1.1e-09 38.0 0.9 2e-09 37.1 0.9 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KIK45338.1 - 6.1e-06 26.5 0.0 1.3e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KIK45338.1 - 3.3e-05 23.2 0.0 5.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KIK45338.1 - 4.7e-05 23.7 0.2 0.029 14.6 0.1 2.3 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 KIK45338.1 - 0.00028 21.3 0.2 0.0097 16.3 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain Prot_ATP_OB_N PF17758.1 KIK45338.1 - 0.00047 19.7 1.2 0.0013 18.4 0.0 2.3 3 0 0 3 3 2 1 Proteasomal ATPase OB N-terminal domain AAA_5 PF07728.14 KIK45338.1 - 0.0005 20.1 0.3 0.0024 17.9 0.3 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KIK45338.1 - 0.00063 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KIK45338.1 - 0.0062 16.7 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KIK45338.1 - 0.0071 16.4 0.1 0.058 13.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KIK45338.1 - 0.0073 15.7 0.2 0.26 10.6 0.1 2.2 1 1 0 2 2 2 1 KaiC AAA_3 PF07726.11 KIK45338.1 - 0.0076 16.1 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KIK45338.1 - 0.0093 16.5 0.0 0.02 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIK45338.1 - 0.027 14.2 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 KIK45338.1 - 0.029 14.6 0.3 0.095 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KIK45338.1 - 0.054 13.4 0.2 0.8 9.6 0.1 2.5 2 1 1 3 3 3 0 NACHT domain TIP49 PF06068.13 KIK45338.1 - 0.083 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Viral_helicase1 PF01443.18 KIK45338.1 - 0.097 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KIK45338.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KIK45338.1 - 0.12 12.1 0.3 0.34 10.6 0.2 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK45338.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KIK45338.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KIK45338.1 - 0.16 11.5 0.8 5.2 6.6 0.3 2.6 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 KIK45338.1 - 0.17 11.6 0.4 0.41 10.3 0.4 1.7 1 1 0 1 1 1 0 AAA domain Yip1 PF04893.17 KIK45339.1 - 7.7e-13 48.5 14.9 1.2e-12 47.9 14.9 1.2 1 0 0 1 1 1 1 Yip1 domain Med26 PF08711.11 KIK45342.1 - 1.5e-10 40.9 0.0 5.1e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain SBP_bac_3 PF00497.20 KIK45345.1 - 0.00032 20.2 0.0 0.0005 19.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 KIK45345.1 - 0.0021 17.7 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein LysR_substrate PF03466.20 KIK45345.1 - 0.012 15.0 0.0 0.076 12.4 0.0 2.1 1 1 0 1 1 1 0 LysR substrate binding domain NMT1 PF09084.11 KIK45345.1 - 0.025 14.5 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 NMT1/THI5 like NMT1_2 PF13379.6 KIK45345.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family NMT1_3 PF16868.5 KIK45345.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family SecG PF03840.14 KIK45346.1 - 0.0022 18.0 5.4 0.0072 16.4 5.4 1.9 1 1 0 1 1 1 1 Preprotein translocase SecG subunit Chlorovi_GP_rpt PF06598.11 KIK45346.1 - 0.03 14.4 0.1 0.061 13.4 0.1 1.5 1 0 0 1 1 1 0 Chlorovirus glycoprotein repeat SelB-wing_3 PF09107.11 KIK45346.1 - 0.084 12.5 0.5 0.48 10.1 0.0 2.1 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Crystall_2 PF09076.10 KIK45350.1 - 0.048 13.5 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 Beta/Gamma crystallin Hormone_1 PF00103.20 KIK45350.1 - 0.17 11.6 0.0 0.23 11.2 0.0 1.1 1 0 0 1 1 1 0 Somatotropin hormone family DUF1143 PF06608.11 KIK45351.1 - 0.2 11.7 1.2 0.59 10.2 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) TPR_2 PF07719.17 KIK45355.1 - 6e-08 32.2 2.9 0.073 13.2 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIK45355.1 - 3.5e-05 24.2 1.8 9.5e-05 22.8 1.5 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK45355.1 - 8.9e-05 22.2 0.8 1.4 8.8 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK45355.1 - 0.00013 22.2 0.8 0.00028 21.1 0.5 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KIK45355.1 - 0.00077 20.1 1.0 0.89 10.5 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK45355.1 - 0.0014 19.3 0.4 0.32 11.7 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIK45355.1 - 0.039 14.2 0.4 4.2 7.7 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIK45355.1 - 0.047 14.3 0.4 31 5.5 0.0 3.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK45355.1 - 0.047 13.9 1.8 0.52 10.7 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4919 PF16266.5 KIK45355.1 - 0.05 13.6 0.1 0.085 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) Saf_2TM PF18303.1 KIK45358.1 - 0.82 9.3 5.5 0.41 10.2 0.9 2.1 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain CAP_N PF01213.19 KIK45360.1 - 0.54 9.7 3.6 0.59 9.6 3.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Claudin_3 PF06653.11 KIK45366.1 - 0.47 10.4 10.5 0.13 12.2 6.6 1.9 1 1 1 2 2 2 0 Tight junction protein, Claudin-like Questin_oxidase PF14027.6 KIK45367.1 - 5.9e-78 262.8 0.0 7e-78 262.5 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like DUF3945 PF13101.6 KIK45369.1 - 0.14 11.9 0.0 0.19 11.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3945) CHAT PF12770.7 KIK45370.1 - 4.4e-31 108.4 0.0 9.8e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK45370.1 - 9.9e-09 34.8 20.6 0.091 12.7 0.0 8.1 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK45370.1 - 2.1e-07 31.1 14.2 0.7 10.2 0.1 8.0 5 3 3 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK45370.1 - 0.00015 21.5 3.1 4.1 7.7 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK45370.1 - 0.00025 20.9 5.5 11 6.4 0.0 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat MIT PF04212.18 KIK45370.1 - 0.0019 18.3 0.0 3.9 7.6 0.0 4.4 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 KIK45370.1 - 0.0046 16.7 5.3 25 4.9 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIK45370.1 - 0.19 12.2 3.1 35 5.1 0.0 4.2 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK45370.1 - 1.1 10.3 16.5 33 5.7 0.0 7.7 9 1 0 9 9 9 0 Tetratricopeptide repeat Vta1_C PF18097.1 KIK45370.1 - 3.1 7.6 8.0 1.1 9.0 0.1 4.0 4 0 0 4 4 4 0 Vta1 C-terminal domain Aminotran_4 PF01063.19 KIK45371.1 - 0.018 14.9 0.0 0.019 14.9 0.0 1.0 1 0 0 1 1 1 0 Amino-transferase class IV NADH-u_ox-rdase PF10785.9 KIK45373.1 - 0.045 14.4 0.3 0.22 12.2 0.3 2.4 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Antimicrobial23 PF16048.5 KIK45375.1 - 0.25 11.0 1.3 0.66 9.7 1.3 1.7 1 0 0 1 1 1 0 Frog antimicrobial peptide Sugar_tr PF00083.24 KIK45376.1 - 3.4e-74 250.3 27.6 3.9e-74 250.1 27.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK45376.1 - 3.3e-25 88.8 58.6 5.3e-24 84.8 31.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex26 PF07163.12 KIK45377.1 - 0.00024 20.5 0.0 0.00049 19.5 0.0 1.5 1 0 0 1 1 1 1 Pex26 protein Adeno_terminal PF02459.15 KIK45377.1 - 0.018 13.5 0.1 0.026 12.9 0.1 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein SecG PF03840.14 KIK45378.1 - 0.068 13.3 0.4 0.068 13.3 0.4 3.3 4 0 0 4 4 4 0 Preprotein translocase SecG subunit CobS PF02654.15 KIK45378.1 - 2.3 8.4 13.5 36 4.4 13.5 2.0 1 1 0 1 1 1 0 Cobalamin-5-phosphate synthase SecG PF03840.14 KIK45379.1 - 0.018 15.1 4.0 0.076 13.1 4.0 2.1 1 1 0 1 1 1 0 Preprotein translocase SecG subunit eIF3_subunit PF08597.10 KIK45383.1 - 1.4e-61 208.5 17.2 1.6e-61 208.3 17.2 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF2935 PF11155.8 KIK45383.1 - 0.038 14.3 0.0 0.063 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) WD40 PF00400.32 KIK45384.1 - 4.4e-17 62.1 3.1 0.004 18.0 0.2 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Transmemb_17 PF09799.9 KIK45386.1 - 0.035 14.7 9.9 0.15 12.6 0.7 3.2 3 0 0 3 3 3 0 Predicted membrane protein TMEM154 PF15102.6 KIK45386.1 - 0.19 11.6 1.7 0.25 11.2 0.0 1.9 1 1 1 2 2 2 0 TMEM154 protein family PNTB_4TM PF12769.7 KIK45386.1 - 4 8.0 10.4 0.61 10.6 5.6 2.1 2 1 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch 5_nucleotid_C PF02872.18 KIK45387.1 - 0.014 15.6 0.3 0.055 13.7 0.0 2.1 3 0 0 3 3 3 0 5'-nucleotidase, C-terminal domain Pkinase_fungal PF17667.1 KIK45388.1 - 2.6e-10 39.7 0.0 2.6e-10 39.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase NACHT PF05729.12 KIK45389.1 - 3.1e-10 40.2 0.0 1.1e-09 38.5 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK45389.1 - 0.00043 20.7 0.0 0.0018 18.7 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain HemolysinCabind PF00353.19 KIK45389.1 - 0.012 15.6 0.0 0.24 11.4 0.0 3.0 3 0 0 3 3 3 0 RTX calcium-binding nonapeptide repeat (4 copies) AAA_18 PF13238.6 KIK45389.1 - 0.041 14.4 0.0 0.12 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK45389.1 - 0.081 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 KIK45389.1 - 0.09 13.1 0.0 0.37 11.1 0.0 2.1 1 1 1 2 2 2 0 AAA domain Syja_N PF02383.18 KIK45390.1 - 9.7e-78 261.7 0.0 1.4e-77 261.1 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain SRAP PF02586.14 KIK45391.1 - 2.4e-61 207.0 0.0 3e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Pan3_PK PF18101.1 KIK45392.1 - 5.1e-63 211.2 0.1 7.5e-63 210.6 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KIK45392.1 - 8.5e-06 25.3 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK45392.1 - 4.3e-05 22.9 0.0 9.5e-05 21.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase ADH_zinc_N PF00107.26 KIK45393.1 - 4.7e-17 62.2 0.0 7.8e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK45393.1 - 2.9e-05 25.1 0.0 5.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK45393.1 - 0.0095 15.8 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.6 KIK45393.1 - 0.019 14.8 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding PG_binding_1 PF01471.18 KIK45393.1 - 0.058 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative peptidoglycan binding domain NmrA PF05368.13 KIK45393.1 - 0.073 12.6 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family PAP_assoc PF03828.19 KIK45394.1 - 1.5e-16 60.3 0.2 3e-16 59.4 0.2 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KIK45394.1 - 3.8e-05 23.9 0.0 0.00019 21.6 0.0 2.1 1 1 1 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 KIK45394.1 - 0.056 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase LSM PF01423.22 KIK45395.1 - 3.3e-19 68.4 0.1 3.9e-19 68.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 KIK45395.1 - 0.048 13.8 0.0 0.19 11.9 0.1 1.8 2 0 0 2 2 2 0 RimP C-terminal SH3 domain HEAT_EZ PF13513.6 KIK45396.1 - 1.3e-16 60.7 13.7 1.2e-11 44.8 0.0 7.7 7 1 1 8 8 8 2 HEAT-like repeat HEAT PF02985.22 KIK45396.1 - 1.5e-14 52.8 12.5 0.00014 21.8 0.0 9.6 11 0 0 11 11 9 2 HEAT repeat Arm PF00514.23 KIK45396.1 - 8.5e-10 38.3 7.1 0.017 15.2 0.0 6.7 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 KIK45396.1 - 2.1e-09 37.1 0.7 5.5e-08 32.6 0.2 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KIK45396.1 - 1.5e-07 31.7 8.4 0.068 13.6 0.0 6.8 5 2 2 7 7 7 3 HEAT repeats DUF3385 PF11865.8 KIK45396.1 - 2.3e-05 24.3 0.6 0.82 9.6 0.2 4.4 4 1 1 5 5 5 2 Domain of unknown function (DUF3385) CLASP_N PF12348.8 KIK45396.1 - 0.0053 16.4 0.0 2.8 7.5 0.0 4.2 2 2 3 5 5 5 1 CLASP N terminal MMS19_C PF12460.8 KIK45396.1 - 0.017 14.3 3.5 1.1 8.3 0.0 3.6 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 KIK45396.1 - 0.017 13.7 0.8 2.4 6.6 0.0 3.6 1 1 3 4 4 4 0 Adaptin N terminal region TIP120 PF08623.10 KIK45396.1 - 0.094 12.5 0.3 0.8 9.5 0.0 2.5 2 1 0 3 3 3 0 TATA-binding protein interacting (TIP20) DRIM PF07539.12 KIK45396.1 - 0.096 11.0 0.1 11 4.2 0.0 3.6 2 1 1 4 4 4 0 Down-regulated in metastasis Lon_C PF05362.13 KIK45397.1 - 4.9e-65 218.9 0.1 7.8e-65 218.3 0.1 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 KIK45397.1 - 3e-23 82.7 0.0 6e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIK45397.1 - 2.4e-11 43.8 0.0 5.7e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) LON_substr_bdg PF02190.16 KIK45397.1 - 4.3e-09 36.6 0.0 8.8e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 KIK45397.1 - 4.4e-06 26.5 0.1 2.6e-05 24.1 0.0 2.3 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 KIK45397.1 - 4.4e-05 23.7 0.0 0.00014 22.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KIK45397.1 - 0.0018 18.7 0.3 0.0018 18.7 0.3 2.9 2 2 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KIK45397.1 - 0.0027 17.9 0.0 0.0064 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIK45397.1 - 0.0029 17.4 0.0 0.013 15.3 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.12 KIK45397.1 - 0.0036 17.1 0.0 0.018 14.8 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KIK45397.1 - 0.0074 15.5 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KIK45397.1 - 0.02 15.2 1.9 0.26 11.6 0.2 2.8 2 1 0 2 2 2 0 AAA domain SKI PF01202.22 KIK45397.1 - 0.034 14.3 0.2 0.38 10.9 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase AAA_18 PF13238.6 KIK45397.1 - 0.036 14.6 0.0 0.14 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KIK45397.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KIK45397.1 - 0.065 13.7 0.8 2 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KIK45397.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 KIK45397.1 - 0.15 11.4 0.2 0.57 9.5 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KIK45397.1 - 0.19 12.2 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 KIK45397.1 - 0.22 11.4 0.0 0.47 10.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Spc7 PF08317.11 KIK45398.1 - 2.9e-05 23.1 19.0 2.9e-05 23.1 19.0 4.6 1 1 4 5 5 5 2 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 KIK45398.1 - 0.002 18.7 6.3 0.002 18.7 6.3 6.5 3 2 3 6 6 6 3 Clathrin-binding domain of Huntingtin-interacting protein 1 Syntaxin_2 PF14523.6 KIK45398.1 - 0.0039 17.5 0.2 0.0039 17.5 0.2 4.9 3 1 1 4 4 4 1 Syntaxin-like protein Jnk-SapK_ap_N PF09744.9 KIK45398.1 - 0.0084 16.3 11.7 0.0084 16.3 11.7 5.7 1 1 4 5 5 5 1 JNK_SAPK-associated protein-1 Hemagglutinin PF00509.18 KIK45398.1 - 3.4 6.0 8.0 1.1 7.6 4.2 2.0 1 1 0 2 2 2 0 Haemagglutinin TPR_14 PF13428.6 KIK45398.1 - 8.7 7.5 6.0 22 6.2 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF948 PF06103.11 KIK45398.1 - 8.9 6.6 21.6 3.5 8.0 1.5 5.1 3 2 0 4 4 4 0 Bacterial protein of unknown function (DUF948) RNA_lig_T4_1 PF09511.10 KIK45401.1 - 8.9e-59 199.0 0.0 6.2e-37 127.6 0.0 2.4 1 1 1 2 2 2 2 RNA ligase tRNA_lig_kinase PF08303.11 KIK45401.1 - 1.8e-27 96.5 0.3 3e-27 95.7 0.3 1.3 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 KIK45401.1 - 2.9e-22 79.4 0.0 5.4e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_18 PF13238.6 KIK45401.1 - 0.11 13.1 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Gelsolin PF00626.22 KIK45403.1 - 0.19 11.7 0.0 0.43 10.5 0.0 1.6 1 0 0 1 1 1 0 Gelsolin repeat Ldh_1_N PF00056.23 KIK45404.1 - 1.4e-45 154.9 0.1 1.9e-45 154.4 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KIK45404.1 - 4.3e-41 140.6 0.0 5.6e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KIK45404.1 - 0.0001 21.5 0.0 0.00017 20.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KIK45404.1 - 0.13 12.7 0.1 0.33 11.4 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain His_Phos_1 PF00300.22 KIK45405.1 - 2.4e-33 115.5 0.1 3.9e-32 111.5 0.1 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ish1 PF10281.9 KIK45406.1 - 1.7e-55 185.0 37.4 4e-11 43.0 4.7 7.7 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.7 KIK45406.1 - 1.2e-08 34.6 2.8 0.92 9.3 0.0 6.4 6 0 0 6 6 6 2 HeH/LEM domain SAP PF02037.27 KIK45406.1 - 0.0001 21.9 0.0 3.5 7.5 0.0 4.2 5 0 0 5 5 5 2 SAP domain LEM PF03020.15 KIK45406.1 - 0.0066 16.0 0.0 16 5.2 0.0 5.2 7 0 0 7 7 7 1 LEM domain TryThrA_C PF12319.8 KIK45406.1 - 0.0077 15.7 20.9 0.085 12.3 9.4 3.1 2 1 1 3 3 3 2 Tryptophan-Threonine-rich plasmodium antigen C terminal Iron_traffic PF04362.14 KIK45406.1 - 0.044 13.5 2.8 0.056 13.1 0.2 2.5 2 1 1 3 3 3 0 Bacterial Fe(2+) trafficking TilS PF09179.11 KIK45406.1 - 0.13 12.8 8.2 5.6 7.5 0.2 5.0 5 0 0 5 5 5 0 TilS substrate binding domain ABATE PF07336.11 KIK45406.1 - 1.1 9.9 15.9 14 6.3 0.4 5.4 4 3 0 5 5 5 0 Putative stress-induced transcription regulator F-box-like PF12937.7 KIK45407.1 - 8.1e-08 32.0 1.1 1.7e-07 31.0 0.1 2.1 2 0 0 2 2 2 1 F-box-like DrsE_2 PF13686.6 KIK45409.1 - 0.021 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family Rimk_N PF18030.1 KIK45409.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 RimK PreATP-grasp domain DUF1290 PF06947.12 KIK45409.1 - 1.1 9.3 6.4 0.61 10.2 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1290) CD20 PF04103.15 KIK45410.1 - 0.0021 18.2 0.1 0.0023 18.0 0.1 1.1 1 0 0 1 1 1 1 CD20-like family Proton_antipo_M PF00361.20 KIK45410.1 - 0.055 12.7 0.5 0.063 12.5 0.5 1.0 1 0 0 1 1 1 0 Proton-conducting membrane transporter Aldo_ket_red PF00248.21 KIK45413.1 - 4.8e-48 163.9 0.0 5.6e-46 157.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KIK45414.1 - 3.5e-50 170.9 0.0 5.8e-48 163.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family RBD PF02196.15 KIK45414.1 - 0.096 12.8 0.0 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 Raf-like Ras-binding domain AA_permease_2 PF13520.6 KIK45415.1 - 1.7e-53 182.0 50.3 1.9e-53 181.8 50.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK45415.1 - 3.5e-11 42.4 44.5 6.7e-11 41.5 44.5 1.3 1 1 0 1 1 1 1 Amino acid permease zf-HYPF PF07503.12 KIK45416.1 - 0.18 11.6 0.4 6.4 6.6 0.1 2.7 1 1 1 2 2 2 0 HypF finger MBOAT_2 PF13813.6 KIK45417.1 - 8.6e-21 74.0 3.5 4e-20 71.9 3.5 2.2 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family KdgT PF03812.13 KIK45417.1 - 0.021 14.1 0.5 0.021 14.1 0.5 1.9 2 0 0 2 2 2 0 2-keto-3-deoxygluconate permease MBOAT_2 PF13813.6 KIK45418.1 - 1.3e-20 73.5 2.5 1.3e-20 73.5 2.5 2.4 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DUF1010 PF06231.11 KIK45418.1 - 0.18 12.4 0.1 0.18 12.4 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1010) PPR_2 PF13041.6 KIK45423.1 - 6.2e-13 48.7 0.0 0.0011 19.1 0.0 6.1 7 0 0 7 7 7 4 PPR repeat family PPR PF01535.20 KIK45423.1 - 6.1e-10 38.7 0.3 4.6 7.7 0.0 6.7 6 0 0 6 6 6 3 PPR repeat PPR_3 PF13812.6 KIK45423.1 - 6.1e-06 26.2 0.0 1.2 9.3 0.0 4.2 4 0 0 4 4 4 2 Pentatricopeptide repeat domain TPR_14 PF13428.6 KIK45423.1 - 0.0002 21.9 1.8 2.4 9.2 0.1 6.2 9 0 0 9 9 9 1 Tetratricopeptide repeat PPR_long PF17177.4 KIK45423.1 - 0.0039 16.6 0.0 0.28 10.5 0.0 3.2 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KIK45423.1 - 0.075 12.8 0.0 7.4 6.4 0.0 4.3 5 0 0 5 5 5 0 PPR repeat ATP13 PF12921.7 KIK45423.1 - 0.076 12.9 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ATPase expression HRI1 PF16815.5 KIK45424.1 - 6.7e-22 78.3 0.0 1.2e-21 77.5 0.0 1.4 1 1 0 1 1 1 1 Protein HRI1 Gp_dh_C PF02800.20 KIK45425.1 - 2.4e-67 225.5 0.0 3.4e-67 225.0 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KIK45425.1 - 3.4e-38 130.0 0.2 6.8e-38 129.1 0.2 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KIK45425.1 - 0.0075 16.4 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus PEMT PF04191.13 KIK45426.1 - 6.6e-13 49.0 1.1 6.8e-12 45.7 0.7 2.1 1 1 1 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 KIK45426.1 - 1.2e-12 48.1 0.4 2.8e-12 46.9 0.1 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 KIK45426.1 - 9.1e-08 31.3 0.1 1.2e-07 30.9 0.1 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF2142 PF09913.9 KIK45426.1 - 0.013 14.3 0.7 0.016 14.1 0.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) AA_permease_2 PF13520.6 KIK45428.1 - 9.6e-43 146.6 50.4 1.2e-42 146.2 50.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK45428.1 - 3.4e-25 88.6 42.5 4.7e-25 88.1 42.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK45429.1 - 7e-47 160.2 57.9 8.7e-47 159.9 57.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK45429.1 - 4e-23 81.8 53.5 5.2e-23 81.4 53.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4112 PF13430.6 KIK45429.1 - 0.077 13.3 2.9 0.08 13.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) DUF1962 PF09227.10 KIK45432.1 - 0.08 13.3 1.4 0.4 11.1 1.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1962) Snapin_Pallidin PF14712.6 KIK45438.1 - 0.00056 20.3 0.9 0.00096 19.5 0.9 1.3 1 0 0 1 1 1 1 Snapin/Pallidin DUF848 PF05852.11 KIK45438.1 - 0.011 15.9 0.2 0.015 15.5 0.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Spc7 PF08317.11 KIK45438.1 - 0.014 14.3 0.6 0.019 13.9 0.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Cortex-I_coil PF09304.10 KIK45438.1 - 0.023 14.9 1.2 0.036 14.3 1.2 1.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil CCDC85 PF10226.9 KIK45438.1 - 0.027 14.1 0.2 0.037 13.7 0.2 1.2 1 0 0 1 1 1 0 CCDC85 family FAM184 PF15665.5 KIK45438.1 - 0.037 13.8 2.3 0.04 13.7 1.3 1.5 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B LMP PF04778.12 KIK45438.1 - 0.043 13.7 0.4 0.062 13.2 0.4 1.2 1 0 0 1 1 1 0 LMP repeated region Tmemb_cc2 PF10267.9 KIK45438.1 - 0.067 12.3 0.2 1 8.4 0.1 1.9 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein TMF_TATA_bd PF12325.8 KIK45438.1 - 0.073 13.3 2.3 0.11 12.7 1.4 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Baculo_PEP_C PF04513.12 KIK45438.1 - 0.079 13.0 0.3 0.11 12.5 0.3 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 KIK45438.1 - 0.13 12.6 1.0 16 6.0 0.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Lectin_N PF03954.14 KIK45438.1 - 0.17 11.6 0.9 0.29 10.9 0.9 1.4 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain CLZ PF16526.5 KIK45438.1 - 0.39 11.1 3.6 3 8.3 0.4 2.2 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 KIK45438.1 - 0.54 10.5 4.8 14 6.0 0.1 2.3 1 1 2 3 3 3 0 ABC transporter C-terminal domain Prefoldin PF02996.17 KIK45438.1 - 1 9.3 4.4 1.9 8.4 0.5 2.2 1 1 1 2 2 2 0 Prefoldin subunit Pro_CA PF00484.19 KIK45439.1 - 2.8e-41 141.4 0.1 3.5e-41 141.1 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Pro_CA PF00484.19 KIK45440.1 - 0.00059 20.2 0.0 0.00076 19.8 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Ras PF00071.22 KIK45441.1 - 2.9e-46 157.0 0.0 3.4e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK45441.1 - 3.4e-21 75.7 0.0 5.2e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK45441.1 - 2.7e-05 23.7 0.0 4.5e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KIK45441.1 - 0.0013 18.2 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KIK45441.1 - 0.058 13.8 0.0 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AMP-binding PF00501.28 KIK45442.1 - 1e-92 311.0 0.1 1.3e-92 310.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK45442.1 - 0.00064 20.6 0.0 0.0017 19.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2104 PF09877.9 KIK45442.1 - 0.0092 16.2 0.2 0.034 14.4 0.1 1.9 2 0 0 2 2 2 1 Predicted membrane protein (DUF2104) PsbJ PF01788.17 KIK45443.1 - 0.056 13.3 0.7 0.095 12.6 0.7 1.3 1 0 0 1 1 1 0 PsbJ gpD PF02925.16 KIK45443.1 - 0.17 11.8 0.5 0.23 11.4 0.5 1.2 1 0 0 1 1 1 0 Bacteriophage scaffolding protein D Terpene_synth_C PF03936.16 KIK45444.1 - 1.4e-07 31.1 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.11 KIK45444.1 - 3e-05 23.1 0.0 4.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Sod_Fe_C PF02777.18 KIK45446.1 - 1.3e-36 124.8 0.1 2.3e-36 124.0 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KIK45446.1 - 5.5e-30 103.7 2.2 5.5e-30 103.7 2.2 2.0 3 0 0 3 3 3 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Ocnus PF05005.15 KIK45446.1 - 0.13 12.4 0.0 0.53 10.4 0.0 1.9 2 0 0 2 2 2 0 Janus/Ocnus family (Ocnus) FAD_binding_3 PF01494.19 KIK45447.1 - 8.5e-18 64.7 0.0 1.4e-16 60.7 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIK45447.1 - 4.2e-08 33.3 0.9 1.2e-07 31.8 0.6 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KIK45447.1 - 4.2e-08 32.9 0.7 5.6e-05 22.6 0.4 2.5 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KIK45447.1 - 1e-07 31.3 1.3 0.0091 15.1 1.2 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KIK45447.1 - 3.1e-07 29.9 0.1 3.3e-05 23.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIK45447.1 - 5.3e-07 28.8 0.2 0.0025 16.7 0.1 2.3 1 1 1 2 2 2 2 Tryptophan halogenase Thi4 PF01946.17 KIK45447.1 - 7e-06 25.5 0.2 1.6e-05 24.3 0.2 1.5 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KIK45447.1 - 7.7e-06 25.7 7.4 9.8e-06 25.4 4.3 2.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK45447.1 - 1.3e-05 24.5 5.1 2e-05 23.9 5.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KIK45447.1 - 0.00043 19.8 4.9 0.00078 18.9 4.9 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIK45447.1 - 0.00051 20.6 0.1 0.0014 19.2 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK45447.1 - 0.001 17.9 1.2 0.0065 15.2 1.2 1.9 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KIK45447.1 - 0.0045 16.1 2.9 0.0091 15.1 2.9 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 KIK45447.1 - 0.13 12.2 0.3 0.22 11.4 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIK45447.1 - 0.13 11.5 0.4 0.32 10.3 0.4 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UPF0227 PF05728.12 KIK45447.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) ApbA PF02558.16 KIK45447.1 - 0.17 11.5 2.1 0.33 10.6 2.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MCRA PF06100.11 KIK45447.1 - 0.22 10.3 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 MCRA family UDPG_MGDP_dh_N PF03721.14 KIK45447.1 - 0.24 11.0 0.4 0.42 10.2 0.4 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.6 KIK45447.1 - 0.28 10.4 4.4 1.6 7.9 4.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIK45449.1 - 1.6e-18 67.1 0.0 4.3e-18 65.7 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIK45449.1 - 6.7e-07 29.5 1.0 1.5e-06 28.3 1.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KIK45449.1 - 1e-06 28.3 3.0 0.00056 19.3 0.7 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KIK45449.1 - 4.8e-06 25.9 4.6 3e-05 23.3 3.1 2.1 1 1 1 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KIK45449.1 - 5.7e-06 25.4 0.4 0.00035 19.5 0.2 2.2 1 1 1 2 2 2 2 Tryptophan halogenase DAO PF01266.24 KIK45449.1 - 6.2e-06 26.0 5.9 3.7e-05 23.5 4.5 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIK45449.1 - 1.2e-05 24.6 1.0 4.2e-05 22.8 1.0 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KIK45449.1 - 1.7e-05 24.2 2.3 0.00048 19.4 2.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK45449.1 - 0.00015 21.1 0.1 0.00015 21.1 0.1 1.6 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KIK45449.1 - 0.0027 17.1 1.6 0.0047 16.3 1.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIK45449.1 - 0.0095 14.7 1.7 0.1 11.3 2.4 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KIK45449.1 - 0.018 15.6 0.1 0.066 13.8 0.1 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIK45449.1 - 0.029 13.4 3.6 0.051 12.7 3.6 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A SE PF08491.10 KIK45449.1 - 0.084 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_3 PF13738.6 KIK45449.1 - 1.3 8.2 3.5 2.6 7.2 3.5 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ABM PF03992.16 KIK45450.1 - 0.13 12.4 0.0 1.7 8.8 0.0 2.2 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase p450 PF00067.22 KIK45453.1 - 7.9e-67 226.0 0.0 9e-67 225.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Apolipoprotein PF01442.18 KIK45453.1 - 0.089 12.7 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Swi5 PF07061.11 KIK45455.1 - 8.7e-16 57.8 0.5 9.4e-16 57.7 0.5 1.0 1 0 0 1 1 1 1 Swi5 RCC1 PF00415.18 KIK45456.1 - 2.7e-27 95.2 11.9 6.1e-06 26.8 0.1 7.6 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KIK45456.1 - 5.9e-12 45.1 22.5 0.0057 16.4 0.0 7.4 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Ammonium_transp PF00909.21 KIK45457.1 - 1.7e-115 385.9 22.2 2e-115 385.7 22.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Glyco_hydro_47 PF01532.20 KIK45459.1 - 3.1e-147 491.2 0.0 3.5e-147 491.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TauD PF02668.16 KIK45462.1 - 1.7e-42 146.1 0.0 2.1e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family zf-C2H2 PF00096.26 KIK45463.1 - 9.6e-12 44.7 11.0 4e-06 27.0 2.5 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK45463.1 - 1.5e-05 25.4 9.8 0.02 15.7 0.9 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK45463.1 - 4.1e-05 23.8 16.8 6.7e-05 23.1 5.9 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 KIK45463.1 - 0.0066 16.8 0.8 0.099 13.1 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KIK45463.1 - 0.023 15.0 0.2 0.047 14.0 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 KIK45463.1 - 0.085 13.5 3.3 3.6 8.3 0.1 2.2 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 KIK45463.1 - 0.23 11.2 2.5 0.63 9.9 2.5 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KIK45463.1 - 0.25 11.7 2.6 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KIK45463.1 - 1.1 9.3 0.0 1.1 9.3 0.0 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KIK45463.1 - 4.1 7.3 11.2 3.5 7.5 0.7 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIK45465.1 - 5.6e-11 42.3 10.3 4.1e-05 23.8 1.8 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK45465.1 - 9.4e-08 32.2 10.8 3.7e-07 30.3 3.5 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK45465.1 - 2.9e-07 30.8 9.3 0.00072 20.2 1.5 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KIK45465.1 - 0.0013 18.7 1.2 0.0013 18.7 1.2 2.7 2 1 0 2 2 2 1 C2H2-type zinc finger FOXP-CC PF16159.5 KIK45465.1 - 0.004 17.7 2.5 0.52 11.0 0.2 2.1 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-RAG1 PF10426.9 KIK45465.1 - 0.022 14.9 0.4 0.055 13.6 0.4 1.6 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain zf-C2H2_aberr PF17017.5 KIK45465.1 - 0.12 12.5 5.8 5.3 7.2 1.2 2.1 1 1 1 2 2 2 0 Aberrant zinc-finger zf-BED PF02892.15 KIK45465.1 - 0.29 11.2 5.8 5.4 7.1 1.2 2.3 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_11 PF16622.5 KIK45465.1 - 0.31 10.8 7.6 0.58 10.0 2.5 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type CHORD PF04968.12 KIK45465.1 - 0.35 11.6 4.2 2.2 9.0 0.2 2.1 1 1 1 2 2 2 0 CHORD zf-H2C2_5 PF13909.6 KIK45465.1 - 0.9 9.3 14.7 0.58 10.0 1.1 2.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KIK45465.1 - 1.8 9.0 5.6 12 6.3 0.4 2.9 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding EF-hand_1 PF00036.32 KIK45466.1 - 2.6e-28 95.4 16.9 4e-09 35.4 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KIK45466.1 - 2.6e-27 95.1 14.6 1.2e-13 51.3 2.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KIK45466.1 - 2e-23 80.3 13.0 2e-08 33.5 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KIK45466.1 - 2.3e-16 59.4 16.2 5.3e-09 35.8 1.4 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KIK45466.1 - 2.5e-12 45.7 12.3 5e-05 22.6 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 KIK45466.1 - 4.6e-11 42.9 1.5 0.00014 22.1 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KIK45466.1 - 5.3e-09 36.0 7.2 0.00023 21.1 0.1 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KIK45466.1 - 0.00052 20.0 2.3 0.2 11.6 0.0 3.5 2 1 1 3 3 3 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 KIK45466.1 - 0.0016 18.7 3.8 0.11 12.8 0.3 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 KIK45466.1 - 0.0073 16.6 2.9 0.23 11.8 0.4 2.5 2 1 0 2 2 2 1 EF-hand domain DUF1636 PF07845.11 KIK45466.1 - 0.021 15.2 0.0 1.3 9.5 0.0 2.5 2 2 2 4 4 4 0 Protein of unknown function (DUF1636) DUF1059 PF06348.11 KIK45466.1 - 0.12 12.7 0.5 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) zf-C2H2 PF00096.26 KIK45467.1 - 5.7e-12 45.4 50.6 0.08 13.4 0.7 8.2 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK45467.1 - 4.4e-11 42.6 44.4 0.28 12.1 0.2 8.3 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK45467.1 - 5.1e-11 42.6 36.5 1.8e-06 28.0 0.1 7.3 7 1 1 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIK45467.1 - 2.8e-10 40.2 34.7 0.00046 20.5 0.4 7.5 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KIK45467.1 - 2.8e-05 24.4 32.2 0.038 14.3 0.4 5.0 2 2 3 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KIK45467.1 - 0.12 12.4 0.2 0.12 12.4 0.2 6.4 7 1 0 7 7 7 0 C2H2-type zinc finger CK_II_beta PF01214.18 KIK45467.1 - 0.26 11.1 12.2 0.43 10.4 1.2 3.6 2 1 1 3 3 3 0 Casein kinase II regulatory subunit AKAP95 PF04988.12 KIK45467.1 - 1.2 9.3 15.2 0.71 10.1 0.5 3.6 2 2 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Pga1 PF10333.9 KIK45468.1 - 0.0091 15.9 0.4 0.37 10.6 0.4 2.7 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator DUF5447 PF17525.2 KIK45468.1 - 0.09 13.2 0.1 0.27 11.7 0.1 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5447) TPR_9 PF13371.6 KIK45469.1 - 0.0026 17.9 0.3 0.0026 17.9 0.3 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Cu_amine_oxid PF01179.20 KIK45470.1 - 7.1e-159 529.1 0.0 8.6e-159 528.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KIK45470.1 - 3.5e-13 49.8 0.0 7.5e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KIK45470.1 - 3.5e-05 24.0 0.0 6.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Yae1_N PF09811.9 KIK45471.1 - 3.6e-11 42.6 4.3 5e-11 42.1 4.3 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal WD40 PF00400.32 KIK45472.1 - 3e-18 65.8 8.2 0.0003 21.5 0.1 6.3 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45472.1 - 4.7e-05 23.6 0.1 1.9 8.8 0.0 4.9 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Rho_RNA_bind PF07497.12 KIK45472.1 - 0.1 12.5 0.0 20 5.1 0.0 2.5 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain zf-met PF12874.7 KIK45473.1 - 0.071 13.5 6.3 0.33 11.4 1.1 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIK45473.1 - 0.86 10.0 8.1 2.6 8.4 0.3 3.2 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KIK45473.1 - 1.3 9.6 7.4 0.15 12.5 2.8 2.0 2 0 0 2 2 2 0 Zinc-finger double domain Dynactin PF12455.8 KIK45475.1 - 7e-89 297.9 0.1 7e-89 297.9 0.1 3.5 4 0 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 KIK45475.1 - 1.2e-22 79.7 0.1 3.5e-22 78.2 0.1 1.8 2 0 0 2 2 2 1 CAP-Gly domain SYF2 PF08231.12 KIK45475.1 - 0.13 12.6 13.4 0.096 13.1 1.2 2.9 3 0 0 3 3 3 0 SYF2 splicing factor MCPVI PF02993.14 KIK45475.1 - 1.1 9.0 0.0 1.1 9.0 0.0 4.4 5 1 0 5 5 5 0 Minor capsid protein VI Raptor_N PF14538.6 KIK45476.1 - 1.9e-60 203.1 0.0 3.8e-60 202.1 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 KIK45476.1 - 0.00058 19.9 0.1 0.006 16.7 0.0 2.8 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.7 KIK45476.1 - 0.014 15.5 0.0 0.091 12.8 0.0 2.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KIK45476.1 - 0.015 15.8 0.1 0.085 13.4 0.0 2.4 2 0 0 2 2 2 0 HEAT-like repeat WD40 PF00400.32 KIK45476.1 - 0.041 14.8 15.7 3.7 8.6 0.2 6.3 6 0 0 6 6 6 0 WD domain, G-beta repeat HEAT_2 PF13646.6 KIK45476.1 - 0.047 14.1 0.0 0.21 12.0 0.0 2.2 1 0 0 1 1 1 0 HEAT repeats ANAPC4_WD40 PF12894.7 KIK45476.1 - 0.13 12.6 0.0 17 5.8 0.0 3.5 3 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Spem1 PF15670.5 KIK45477.1 - 0.047 13.3 1.0 0.058 13.0 1.0 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 Enolase_C PF00113.22 KIK45478.1 - 4.9e-141 469.2 0.1 7.1e-141 468.7 0.1 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KIK45478.1 - 1e-56 190.7 0.1 1.6e-56 190.1 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KIK45478.1 - 1.2e-05 24.9 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KIK45478.1 - 0.02 14.1 0.1 0.042 13.0 0.1 1.5 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus NGP1NT PF08153.12 KIK45479.1 - 4.5e-50 169.2 0.1 8.8e-50 168.2 0.1 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KIK45479.1 - 9.3e-18 64.4 0.1 1.1e-13 51.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KIK45479.1 - 2.3e-05 23.9 0.3 0.00024 20.7 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KIK45479.1 - 4.3e-05 23.5 0.0 0.00012 22.1 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KIK45479.1 - 0.00015 21.4 0.0 0.034 13.7 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KIK45479.1 - 0.015 14.8 0.0 0.38 10.2 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 KIK45479.1 - 0.078 13.2 0.1 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KIK45479.1 - 0.32 11.0 4.9 8.8 6.4 0.1 3.8 3 1 1 4 4 4 0 Dynamin family Ribosomal_S15 PF00312.22 KIK45480.1 - 3.4e-24 84.9 0.0 6.7e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S15 F-box PF00646.33 KIK45481.1 - 1.3e-05 24.9 0.2 4.1e-05 23.3 0.2 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK45481.1 - 0.00068 19.5 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like ArfGap PF01412.18 KIK45481.1 - 0.046 13.8 1.3 0.22 11.6 1.3 2.2 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf IBN_N PF03810.19 KIK45482.1 - 4.7e-11 42.4 2.4 1.9e-09 37.3 0.1 3.9 4 0 0 4 4 4 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.15 KIK45482.1 - 0.0017 16.9 0.0 0.038 12.5 0.0 2.6 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus F-box-like PF12937.7 KIK45485.1 - 2e-06 27.6 0.2 5.2e-06 26.3 0.2 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIK45485.1 - 0.013 15.9 2.3 0.31 11.5 0.2 3.2 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Prok-JAB PF14464.6 KIK45485.1 - 0.058 13.2 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain Dor1 PF04124.12 KIK45486.1 - 1.3e-34 119.4 0.8 1.3e-21 76.7 2.1 2.8 2 1 0 2 2 2 2 Dor1-like family Sugar_tr PF00083.24 KIK45487.1 - 7.2e-128 427.3 18.5 8.2e-128 427.1 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK45487.1 - 1.3e-15 57.2 22.4 1.3e-15 57.2 22.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Terpene_synth_C PF03936.16 KIK45488.1 - 0.00013 21.4 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Inositol_P PF00459.25 KIK45491.1 - 2.2e-67 227.5 0.0 2.6e-67 227.2 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Proteasome PF00227.26 KIK45492.1 - 7.8e-58 195.1 0.1 9.7e-58 194.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIK45492.1 - 6.2e-14 51.3 0.0 1.3e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Aldo_ket_red PF00248.21 KIK45493.1 - 7.8e-48 163.2 0.0 8.8e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family G-alpha PF00503.20 KIK45494.1 - 3.4e-118 394.8 0.0 4.7e-118 394.4 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK45494.1 - 1.3e-14 54.1 0.1 4.5e-10 39.3 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KIK45494.1 - 0.00016 21.8 0.2 1 9.6 0.0 2.7 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KIK45494.1 - 0.0013 18.1 0.1 0.0033 16.9 0.0 1.6 2 0 0 2 2 2 1 Bacterial TniB protein DUF3599 PF12206.8 KIK45494.1 - 0.004 17.5 0.0 0.0093 16.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3599) GTP_EFTU PF00009.27 KIK45494.1 - 0.0098 15.5 0.0 0.57 9.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KIK45494.1 - 0.012 15.0 1.8 0.42 9.9 0.1 2.6 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 KIK45494.1 - 0.035 13.8 0.3 0.083 12.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain DAP3 PF10236.9 KIK45494.1 - 0.035 13.3 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 KIK45494.1 - 0.065 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KIK45494.1 - 0.073 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 KIK45494.1 - 0.11 12.7 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Glyco_transf_11 PF01531.16 KIK45495.1 - 0.034 13.3 0.1 0.04 13.1 0.1 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 11 EphA2_TM PF14575.6 KIK45496.1 - 0.11 13.4 0.0 0.26 12.2 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KIK45496.1 - 0.38 10.7 0.0 0.38 10.7 0.0 6.1 3 1 2 5 5 5 0 TMEM154 protein family DASH_Ask1 PF08655.10 KIK45497.1 - 2.7e-10 40.0 0.1 4.9e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 Nucleoporin_FG PF13634.6 KIK45497.1 - 1.2 10.0 12.6 8.6 7.3 2.5 2.7 2 0 0 2 2 2 0 Nucleoporin FG repeat region CPSase_L_D2 PF02786.17 KIK45498.1 - 6.3e-76 254.6 0.0 1e-75 253.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KIK45498.1 - 1.1e-46 157.9 0.2 4.6e-46 155.9 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KIK45498.1 - 3.1e-30 104.5 0.0 2.1e-23 82.5 0.0 2.6 2 0 0 2 2 2 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KIK45498.1 - 1.2e-14 53.9 2.8 2.4e-14 52.9 2.8 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KIK45498.1 - 2.6e-11 43.5 0.2 8.8e-11 41.7 0.0 1.9 2 1 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KIK45498.1 - 8.7e-10 38.4 0.0 2.5e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KIK45498.1 - 0.00055 19.7 0.3 0.0029 17.4 0.2 2.2 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 KIK45498.1 - 0.001 19.1 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KIK45498.1 - 0.0038 17.9 0.6 3.7 8.3 0.0 2.7 2 0 0 2 2 2 2 HlyD family secretion protein GARS_A PF01071.19 KIK45498.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_D23 PF16576.5 KIK45498.1 - 0.014 14.6 0.6 1.6 7.9 0.1 2.4 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Ntox43 PF15537.6 KIK45498.1 - 0.018 15.1 0.0 0.046 13.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial toxin 43 ATP-grasp_4 PF13535.6 KIK45498.1 - 0.044 13.4 0.0 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_ST PF14397.6 KIK45498.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp DUF768 PF05589.11 KIK45498.1 - 0.26 11.3 0.7 21 5.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF768) Dus PF01207.17 KIK45499.1 - 1e-48 166.0 0.0 2.6e-48 164.7 0.0 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Radical_SAM PF04055.21 KIK45499.1 - 0.021 15.2 0.2 0.096 13.1 0.1 1.9 2 0 0 2 2 2 0 Radical SAM superfamily AP_endonuc_2 PF01261.24 KIK45499.1 - 0.13 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel RNase_P_pop3 PF08228.11 KIK45502.1 - 0.089 12.8 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 NACHT PF05729.12 KIK45503.1 - 4e-13 49.6 0.1 1.7e-12 47.6 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KIK45503.1 - 1.9e-06 28.4 0.0 4.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK45503.1 - 0.00013 22.2 0.0 0.00033 20.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Anti-TRAP PF15777.5 KIK45503.1 - 0.022 14.7 4.8 33 4.5 0.0 6.4 6 1 1 7 7 7 0 Tryptophan RNA-binding attenuator protein inhibitory protein NB-ARC PF00931.22 KIK45503.1 - 0.025 13.8 0.1 0.05 12.8 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 KIK45503.1 - 0.041 14.3 0.1 0.12 12.8 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK45503.1 - 0.057 13.8 0.1 0.13 12.7 0.1 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KIK45503.1 - 0.12 12.9 0.1 0.32 11.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KIK45503.1 - 0.15 11.3 0.1 0.39 9.9 0.1 1.7 1 1 0 1 1 1 0 KAP family P-loop domain APS_kinase PF01583.20 KIK45503.1 - 0.24 11.3 0.7 0.41 10.5 0.1 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase ADH_zinc_N PF00107.26 KIK45504.1 - 5.4e-12 45.8 0.0 1.1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK45504.1 - 4.4e-08 33.0 0.0 8.2e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIK45504.1 - 0.0049 17.9 0.1 0.0096 17.0 0.1 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Ribonuc_L-PSP PF01042.21 KIK45505.1 - 2.5e-43 147.0 0.1 2.7e-43 146.8 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP RPN1_RPN2_N PF17781.1 KIK45505.1 - 0.0046 16.4 0.0 0.0054 16.2 0.0 1.1 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain WD40 PF00400.32 KIK45506.1 - 3.1e-09 37.3 0.0 2.7e-06 28.0 0.0 2.7 2 1 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45506.1 - 0.00064 20.0 0.0 0.028 14.7 0.0 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ret2_MD PF18528.1 KIK45506.1 - 0.048 14.0 0.0 0.14 12.6 0.0 1.7 1 1 0 1 1 1 0 RNA editing 3' terminal uridylyl transferase 2 middle domain amfpi-1 PF12190.8 KIK45507.1 - 0.044 14.4 0.9 0.045 14.4 0.9 1.1 1 0 0 1 1 1 0 Fungal protease inhibitor WD40 PF00400.32 KIK45508.1 - 5.6e-14 52.3 5.4 0.018 15.9 0.1 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45508.1 - 0.027 14.8 0.0 12 6.2 0.0 3.6 2 2 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain F-box-like_2 PF13013.6 KIK45508.1 - 0.08 12.9 0.4 0.3 11.1 0.0 2.1 3 0 0 3 3 3 0 F-box-like domain CCSMST1 PF15013.6 KIK45509.1 - 0.01 16.0 0.2 0.027 14.7 0.0 1.8 2 0 0 2 2 2 0 CCSMST1 family CHAT PF12770.7 KIK45510.1 - 7e-34 117.6 0.1 8.4e-34 117.3 0.1 1.0 1 0 0 1 1 1 1 CHAT domain DUF3463 PF11946.8 KIK45511.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) RexB PF15968.5 KIK45512.1 - 0.0064 17.0 10.8 0.011 16.2 3.3 2.4 2 0 0 2 2 2 2 Membrane-anchored ion channel, Abi component Ino80_Iec3 PF14612.6 KIK45513.1 - 0.0061 17.2 0.0 0.007 17.1 0.0 1.2 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling HSF_DNA-bind PF00447.17 KIK45516.1 - 3e-29 101.5 0.8 3.3e-29 101.3 0.8 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Pkinase_Tyr PF07714.17 KIK45517.1 - 7.5e-38 130.3 0.0 1e-37 129.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK45517.1 - 4.2e-34 118.1 0.0 5.9e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LisH PF08513.11 KIK45518.1 - 0.00088 19.1 0.1 0.0016 18.3 0.1 1.4 1 0 0 1 1 1 1 LisH START PF01852.19 KIK45519.1 - 3.7e-22 78.8 0.3 1.2e-09 37.9 0.0 4.1 4 0 0 4 4 4 3 START domain DUF4797 PF16051.5 KIK45519.1 - 0.028 14.4 0.0 0.1 12.6 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4797) DUF3099 PF11298.8 KIK45519.1 - 0.06 13.5 0.1 0.17 12.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) Phos_pyr_kin PF08543.12 KIK45520.1 - 1.7e-09 37.4 0.0 2.8e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KIK45520.1 - 4e-05 23.1 0.0 7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF5316 PF17247.2 KIK45520.1 - 0.016 15.2 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5316) ATP_sub_h PF10775.9 KIK45524.1 - 0.12 12.3 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 ATP synthase complex subunit h Flavin_Reduct PF01613.18 KIK45527.1 - 0.082 12.9 0.1 0.082 12.9 0.1 1.1 1 0 0 1 1 1 0 Flavin reductase like domain DUF4040 PF13244.6 KIK45528.1 - 0.09 12.9 3.7 0.53 10.5 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4040) NAM-associated PF14303.6 KIK45529.1 - 0.00095 19.9 0.0 0.014 16.1 0.0 2.3 1 1 0 1 1 1 1 No apical meristem-associated C-terminal domain Syndecan PF01034.20 KIK45529.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.15 KIK45529.1 - 0.22 11.3 0.1 0.38 10.6 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MGC-24 PF05283.11 KIK45529.1 - 0.64 10.5 37.1 0.097 13.1 20.0 3.0 1 1 2 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Apt1 PF10351.9 KIK45529.1 - 1.9 7.2 8.6 2.6 6.8 8.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain NR_Repeat PF14046.6 KIK45529.1 - 8.2 6.6 7.1 5.9 7.1 0.6 3.1 1 1 1 2 2 2 0 Nuclear receptor repeat Actin PF00022.19 KIK45531.1 - 6e-116 387.4 0.0 2.7e-115 385.3 0.0 1.7 1 1 0 1 1 1 1 Actin MFS_1 PF07690.16 KIK45532.1 - 7.6e-32 110.6 36.1 7.6e-32 110.6 36.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KIK45532.1 - 4.2e-06 25.9 2.1 0.014 14.3 0.0 2.5 2 1 0 2 2 2 2 MFS_1 like family PMP22_Claudin PF00822.20 KIK45532.1 - 0.48 10.3 9.4 0.055 13.4 1.2 3.1 4 0 0 4 4 4 0 PMP-22/EMP/MP20/Claudin family Mito_carr PF00153.27 KIK45533.1 - 5e-55 183.4 1.0 2.3e-18 65.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tocopherol_cycl PF14249.6 KIK45535.1 - 0.059 12.5 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 Tocopherol cyclase MFS_1 PF07690.16 KIK45536.1 - 2e-36 125.7 62.2 3.9e-24 85.2 33.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily IlvN PF07991.12 KIK45537.1 - 1e-46 158.5 0.0 1.8e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KIK45537.1 - 1.1e-37 129.5 0.0 1.8e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain DPPIV_N PF00930.21 KIK45540.1 - 4.4e-95 318.5 0.7 6.3e-95 317.9 0.7 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KIK45540.1 - 6.7e-45 153.2 1.3 1e-44 152.5 1.3 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KIK45540.1 - 5.7e-07 29.4 0.8 1.8e-06 27.8 0.6 1.6 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KIK45540.1 - 7.9e-07 29.0 0.1 1.4e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK45540.1 - 0.0011 19.6 0.1 0.006 17.2 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family PD40 PF07676.12 KIK45540.1 - 0.0019 18.1 3.0 0.27 11.2 0.1 2.9 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat AXE1 PF05448.12 KIK45540.1 - 0.0052 15.5 0.0 0.013 14.2 0.0 1.6 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 KIK45540.1 - 0.01 15.4 0.2 0.075 12.6 0.2 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family COesterase PF00135.28 KIK45540.1 - 0.016 14.1 0.1 0.026 13.4 0.1 1.3 1 0 0 1 1 1 0 Carboxylesterase family CSD2 PF17876.1 KIK45540.1 - 0.097 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Cold shock domain SYS1 PF09801.9 KIK45541.1 - 2.8e-24 85.9 7.0 2.5e-17 63.4 5.6 2.1 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network BCS1_N PF08740.11 KIK45543.1 - 5.7e-36 124.2 3.8 5.7e-36 124.2 3.8 2.9 2 1 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KIK45543.1 - 6.7e-15 55.7 0.0 3.1e-14 53.5 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK45543.1 - 0.00024 21.5 4.8 0.0019 18.6 0.2 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KIK45543.1 - 0.0025 18.0 0.0 0.0025 18.0 0.0 2.5 3 1 0 3 3 1 1 AAA domain AAA_11 PF13086.6 KIK45543.1 - 0.0094 15.8 12.5 5 6.8 12.3 2.3 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KIK45543.1 - 0.011 15.5 0.0 0.011 15.5 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase XRN_M PF17846.1 KIK45543.1 - 0.017 14.1 7.0 0.026 13.5 7.0 1.2 1 0 0 1 1 1 0 Xrn1 helical domain YlbE PF14003.6 KIK45543.1 - 0.025 15.0 0.1 0.078 13.4 0.1 1.8 1 0 0 1 1 1 0 YlbE-like protein NACHT PF05729.12 KIK45543.1 - 0.049 13.5 0.2 0.29 11.1 0.1 2.3 2 0 0 2 2 2 0 NACHT domain RuvB_N PF05496.12 KIK45543.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_23 PF13476.6 KIK45543.1 - 0.15 12.5 12.7 6.6 7.2 12.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KIK45543.1 - 0.19 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RPOL_N PF14700.6 KIK45543.1 - 0.23 10.8 11.8 0.37 10.1 11.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal DDRGK PF09756.9 KIK45543.1 - 0.36 10.4 26.4 90 2.6 31.0 2.4 2 0 0 2 2 2 0 DDRGK domain TERB2 PF15101.6 KIK45543.1 - 0.8 9.7 9.0 2.1 8.3 9.0 1.7 1 0 0 1 1 1 0 Telomere-associated protein TERB2 GAGA_bind PF06217.12 KIK45543.1 - 0.93 9.7 10.9 1.5 9.0 10.9 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family NPR3 PF03666.13 KIK45543.1 - 1.3 7.7 16.6 2.3 6.9 16.6 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ABC_tran PF00005.27 KIK45543.1 - 3.1 8.3 6.3 3.3 8.2 0.1 2.6 2 0 0 2 2 2 0 ABC transporter Cwf_Cwc_15 PF04889.12 KIK45543.1 - 4 7.1 27.6 0.51 10.0 22.3 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TP53IP5 PF15331.6 KIK45543.1 - 4.6 7.3 17.3 8.4 6.5 17.3 1.5 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Med19 PF10278.9 KIK45543.1 - 7.8 6.4 19.5 15 5.5 19.5 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Plasmodium_Vir PF05795.11 KIK45543.1 - 8.6 5.7 14.7 17 4.7 14.7 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Dynamin_M PF01031.20 KIK45544.1 - 2.4e-106 355.1 0.0 4.6e-106 354.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KIK45544.1 - 2.3e-54 184.0 0.0 4e-54 183.2 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KIK45544.1 - 8.8e-30 102.7 1.6 2.6e-29 101.2 0.9 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIK45544.1 - 0.00022 21.3 0.0 0.00071 19.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KIK45544.1 - 0.064 13.6 0.0 0.4 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Mt_ATP-synt_B PF05405.14 KIK45545.1 - 8.1e-45 152.4 10.7 1e-44 152.0 10.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Peptidase_C10 PF01640.17 KIK45545.1 - 0.11 12.8 0.5 0.24 11.7 0.5 1.5 1 1 0 1 1 1 0 Peptidase C10 family DUF5623 PF18536.1 KIK45545.1 - 0.19 12.0 2.9 0.26 11.6 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5623) DUF1539 PF07560.11 KIK45545.1 - 0.21 11.7 3.1 0.59 10.2 3.1 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) SLATT_1 PF18181.1 KIK45545.1 - 0.22 11.5 7.3 0.12 12.3 4.7 1.8 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Virulence_fact PF13769.6 KIK45545.1 - 0.42 10.9 3.8 10 6.4 1.2 2.6 2 0 0 2 2 2 0 Virulence factor DASH_Duo1 PF08651.10 KIK45545.1 - 3.2 7.6 6.9 22 4.9 0.1 2.9 2 1 1 3 3 3 0 DASH complex subunit Duo1 Mito_carr PF00153.27 KIK45549.1 - 7.2e-56 186.1 2.8 4.5e-20 71.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CMD PF02627.20 KIK45550.1 - 0.00075 19.5 0.0 0.0017 18.4 0.0 1.7 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family CMD PF02627.20 KIK45551.1 - 0.00023 21.1 0.0 0.0009 19.2 0.0 2.0 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Cofilin_ADF PF00241.20 KIK45553.1 - 1.5e-22 79.6 0.0 2.9e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_9 PF14604.6 KIK45553.1 - 1.3e-12 47.3 0.2 2.2e-12 46.6 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIK45553.1 - 8.6e-12 44.5 0.3 1.6e-11 43.6 0.3 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KIK45553.1 - 2.3e-07 30.4 0.0 4.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF5341 PF17276.2 KIK45553.1 - 0.081 13.1 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5341) MliC PF09864.9 KIK45553.1 - 0.12 12.4 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme RNase_H2_suC PF08615.11 KIK45555.1 - 1.7e-22 80.1 0.0 2.3e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) GPI-anchored PF10342.9 KIK45556.1 - 2.9e-06 27.9 1.5 2.9e-06 27.9 1.5 2.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2470 PF10615.9 KIK45557.1 - 2.2e-16 60.2 0.0 3.5e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 KIK45557.1 - 3.9e-06 27.1 0.3 7.3e-06 26.2 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) DPM3 PF08285.11 KIK45559.1 - 9.8e-33 112.2 0.0 1.1e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Nab6_mRNP_bdg PF10567.9 KIK45559.1 - 0.012 15.1 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 RNA-recognition motif Polysacc_deac_1 PF01522.21 KIK45560.1 - 1.7e-14 53.8 0.0 3.2e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KIK45560.1 - 2.6e-06 27.3 0.4 5.6e-06 26.2 0.4 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KIK45560.1 - 0.05 12.0 0.0 0.066 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) La_HTH_kDCL PF18177.1 KIK45560.1 - 0.064 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain COesterase PF00135.28 KIK45561.1 - 1.7e-55 188.8 0.0 3.4e-55 187.9 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIK45561.1 - 4.2e-06 26.8 0.1 1.1e-05 25.4 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Polysacc_deac_1 PF01522.21 KIK45562.1 - 2.8e-16 59.5 0.0 8.9e-16 57.9 0.0 1.8 1 1 1 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 KIK45562.1 - 2e-05 24.3 0.3 6.6e-05 22.7 0.2 2.0 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Polysacc_deac_1 PF01522.21 KIK45563.1 - 5.3e-14 52.2 0.0 1.1e-13 51.1 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 KIK45563.1 - 1.5e-05 24.8 0.6 4e-05 23.4 0.3 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KIK45563.1 - 0.079 11.3 0.0 0.1 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) AA_permease_2 PF13520.6 KIK45564.1 - 4.8e-51 173.9 57.4 6e-51 173.6 57.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK45564.1 - 1.7e-14 53.3 53.1 3.1e-14 52.4 52.4 1.6 1 1 1 2 2 2 1 Amino acid permease Arginase PF00491.21 KIK45565.1 - 6e-87 291.7 0.0 7.7e-87 291.3 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KIK45565.1 - 0.05 13.8 0.0 0.081 13.2 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain MatE PF01554.18 KIK45566.1 - 6.1e-51 172.3 25.5 1.9e-27 95.9 4.1 2.8 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KIK45566.1 - 0.0024 17.9 5.3 0.0024 17.9 5.3 4.2 5 0 0 5 5 5 2 Polysaccharide biosynthesis C-terminal domain UPF0242 PF06785.11 KIK45566.1 - 0.091 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Thioredoxin PF00085.20 KIK45567.1 - 3.5e-21 75.1 0.0 5.2e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KIK45567.1 - 0.00056 20.2 0.0 0.29 11.5 0.0 3.0 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KIK45567.1 - 0.00078 19.9 0.0 0.0018 18.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 KIK45567.1 - 0.00081 19.1 0.1 0.24 11.1 0.0 2.5 2 1 1 3 3 3 2 Redoxin Thioredoxin_9 PF14595.6 KIK45567.1 - 0.0048 16.7 0.0 0.0078 16.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KIK45567.1 - 0.013 15.4 0.0 0.063 13.2 0.0 1.9 2 0 0 2 2 2 0 AhpC/TSA family Thioredoxin_7 PF13899.6 KIK45567.1 - 0.02 15.1 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like zf-RING_UBOX PF13445.6 KIK45568.1 - 5.4e-05 23.1 6.3 5.4e-05 23.1 6.3 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIK45568.1 - 0.00078 19.3 12.6 0.013 15.3 4.4 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK45568.1 - 0.001 19.3 7.1 0.001 19.3 7.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK45568.1 - 0.0017 18.2 6.3 0.0017 18.2 6.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF3584 PF12128.8 KIK45568.1 - 0.0024 15.5 6.5 0.0031 15.1 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) CIAPIN1 PF05093.13 KIK45568.1 - 0.0045 17.5 1.7 0.0045 17.5 1.7 1.9 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis zf-C3HC4 PF00097.25 KIK45568.1 - 0.0052 16.6 6.1 0.0052 16.6 6.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KIK45568.1 - 0.0061 16.4 0.9 0.011 15.5 0.9 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KIK45568.1 - 0.0085 16.2 5.3 0.0085 16.2 5.3 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KIK45568.1 - 0.041 14.0 3.8 0.041 14.0 3.8 2.2 3 0 0 3 3 3 0 zinc RING finger of MSL2 SWIRM-assoc_1 PF16495.5 KIK45568.1 - 0.051 13.5 6.2 0.098 12.6 6.2 1.5 1 0 0 1 1 1 0 SWIRM-associated region 1 UPF0242 PF06785.11 KIK45568.1 - 0.095 12.8 7.5 0.13 12.3 7.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 KIK45568.1 - 0.11 11.3 6.6 0.16 10.8 6.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF16 PF01519.16 KIK45568.1 - 0.12 12.8 3.3 0.32 11.5 3.3 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF16 zf-RING_5 PF14634.6 KIK45568.1 - 0.13 12.3 15.1 0.053 13.5 6.0 2.4 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KIK45568.1 - 0.36 10.7 12.8 1.9 8.4 6.1 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Uso1_p115_C PF04871.13 KIK45568.1 - 0.51 10.7 10.2 0.87 10.0 10.2 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HIP1_clath_bdg PF16515.5 KIK45568.1 - 0.53 10.9 10.3 1.1 10.0 10.3 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GrpE PF01025.19 KIK45568.1 - 4.6 6.9 10.1 0.97 9.1 5.9 1.8 1 1 1 2 2 2 0 GrpE Macoilin PF09726.9 KIK45568.1 - 4.6 5.7 10.7 5.8 5.3 10.7 1.1 1 0 0 1 1 1 0 Macoilin family Fzo_mitofusin PF04799.13 KIK45568.1 - 6.2 6.3 7.5 9.9 5.7 7.5 1.2 1 0 0 1 1 1 0 fzo-like conserved region SlyX PF04102.12 KIK45568.1 - 9.2 7.0 8.9 38 5.0 7.9 2.3 1 1 1 2 2 2 0 SlyX STT3 PF02516.14 KIK45569.1 - 1.2e-144 483.0 25.4 2.6e-138 462.0 22.2 2.2 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 KIK45569.1 - 6.5e-05 23.2 10.2 6.5e-05 23.2 10.2 2.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase U3_snoRNA_assoc PF08297.11 KIK45569.1 - 0.017 15.8 1.2 0.033 14.9 1.2 1.4 1 0 0 1 1 1 0 U3 snoRNA associated Mucin PF01456.17 KIK45569.1 - 0.021 14.8 6.9 0.04 13.9 6.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Ran_BP1 PF00638.18 KIK45570.1 - 0.0003 21.0 0.0 0.00048 20.4 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain zf-HC5HC2H_2 PF13832.6 KIK45573.1 - 6.8e-32 109.9 12.5 4.9e-31 107.1 6.0 2.8 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KIK45573.1 - 1.2e-23 83.1 4.4 1.2e-23 83.1 4.4 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.9 KIK45573.1 - 1.3e-23 84.1 0.5 1.3e-23 84.1 0.5 2.7 2 1 0 2 2 1 1 Enhancer of polycomb-like Bromodomain PF00439.25 KIK45573.1 - 5.4e-18 64.9 0.0 1.3e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 KIK45573.1 - 3.2e-15 55.4 9.0 9.1e-15 53.9 3.0 2.7 2 0 0 2 2 2 1 PHD-finger PWWP PF00855.17 KIK45573.1 - 1.6e-13 50.9 0.7 4.4e-13 49.4 0.7 1.8 1 0 0 1 1 1 1 PWWP domain PHD PF00628.29 KIK45573.1 - 1.8e-11 43.7 17.2 1.5e-10 40.8 5.7 2.7 2 0 0 2 2 2 2 PHD-finger Trypan_PARP PF05887.11 KIK45573.1 - 0.0012 18.8 14.4 0.0012 18.8 14.4 2.8 2 1 0 2 2 1 1 Procyclic acidic repetitive protein (PARP) zf-PHD-like PF15446.6 KIK45573.1 - 0.0029 17.3 0.8 0.0029 17.3 0.8 2.5 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 KIK45573.1 - 0.0071 16.2 0.5 0.0071 16.2 0.5 2.7 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) NapB PF03892.14 KIK45573.1 - 0.013 15.5 0.0 0.058 13.4 0.0 2.1 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) FYVE_2 PF02318.16 KIK45573.1 - 0.022 15.0 0.4 0.022 15.0 0.4 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RanBP PF00641.18 KIK45573.1 - 2 7.8 7.9 0.7 9.3 0.3 3.2 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others TFIIA PF03153.13 KIK45573.1 - 3.1 7.7 12.5 6.4 6.7 12.5 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-MYND PF01753.18 KIK45574.1 - 4.3e-08 33.1 9.8 1.6e-07 31.3 9.8 2.1 1 1 0 1 1 1 1 MYND finger DUF5442 PF17514.2 KIK45574.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5442) zf-C6H2 PF15801.5 KIK45574.1 - 0.68 10.3 7.6 2.4 8.6 7.6 1.9 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF420 PF04238.12 KIK45577.1 - 0.032 14.5 3.5 0.039 14.2 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF420) Phtf-FEM1B_bdg PF12129.8 KIK45577.1 - 2 8.2 6.5 3.2 7.6 6.5 1.3 1 1 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor COPIIcoated_ERV PF07970.12 KIK45579.1 - 3.2e-78 262.6 0.2 4.1e-78 262.2 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KIK45579.1 - 3.3e-26 91.4 1.4 3.7e-26 91.3 0.1 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Cerato-platanin PF07249.12 KIK45581.1 - 2.1e-31 108.5 0.2 2.4e-31 108.3 0.2 1.0 1 0 0 1 1 1 1 Cerato-platanin Cerato-platanin PF07249.12 KIK45585.1 - 2.6e-35 121.1 1.0 3e-35 120.9 1.0 1.0 1 0 0 1 1 1 1 Cerato-platanin Plant_tran PF04827.14 KIK45585.1 - 0.049 13.2 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 Plant transposon protein TMF_DNA_bd PF12329.8 KIK45587.1 - 2.3 8.3 9.1 0.78 9.8 2.7 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HA2 PF04408.23 KIK45588.1 - 9.1e-22 77.4 0.0 1.9e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIK45588.1 - 2.8e-21 75.7 0.0 7.1e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIK45588.1 - 3.7e-09 36.9 0.0 1.1e-08 35.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK45588.1 - 8.7e-06 25.6 0.4 1.9e-05 24.5 0.4 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.22 KIK45588.1 - 1.2e-05 25.1 0.6 1.2e-05 25.1 0.6 2.1 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 KIK45588.1 - 0.00028 21.2 0.2 0.00079 19.8 0.2 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK45588.1 - 0.0011 19.3 0.0 0.0034 17.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KIK45588.1 - 0.0055 15.8 0.0 0.013 14.6 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 KIK45588.1 - 0.0062 16.5 0.3 0.016 15.1 0.3 1.7 1 0 0 1 1 1 1 Flavivirus DEAD domain DUF2075 PF09848.9 KIK45588.1 - 0.027 13.7 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KIK45588.1 - 0.042 13.6 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK45588.1 - 0.066 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KIK45588.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Peptidase_S9 PF00326.21 KIK45589.1 - 2.9e-46 157.6 0.1 4.6e-46 157.0 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2920 PF11144.8 KIK45589.1 - 0.063 12.4 0.0 0.46 9.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) HA2 PF04408.23 KIK45590.1 - 2.4e-20 72.8 0.0 5.2e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIK45590.1 - 1.9e-18 66.6 0.0 9e-18 64.4 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIK45590.1 - 1.8e-10 41.1 0.0 7.9e-10 39.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KIK45590.1 - 7e-06 26.4 0.3 2.9e-05 24.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 KIK45590.1 - 8.1e-05 22.5 2.2 0.00011 22.0 1.0 1.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KIK45590.1 - 0.00018 21.9 0.3 0.00039 20.8 0.3 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KIK45590.1 - 0.00089 18.9 0.5 0.0029 17.3 0.1 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 KIK45590.1 - 0.0024 17.0 0.5 0.0052 15.9 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 KIK45590.1 - 0.0037 17.3 0.2 0.009 16.0 0.2 1.7 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_7 PF12775.7 KIK45590.1 - 0.006 16.1 0.1 0.016 14.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF2075 PF09848.9 KIK45590.1 - 0.0085 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KIK45590.1 - 0.031 14.0 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KIK45590.1 - 0.035 13.6 0.1 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 KIK45590.1 - 0.066 12.5 0.2 0.4 10.0 0.0 2.2 2 0 0 2 2 2 0 KaiC ResIII PF04851.15 KIK45590.1 - 0.084 12.9 3.6 0.23 11.5 0.8 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit HTH_IclR PF09339.10 KIK45590.1 - 0.12 12.2 0.1 0.28 11.0 0.1 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain AAA_14 PF13173.6 KIK45590.1 - 0.15 12.1 0.2 3 7.9 0.2 2.4 1 1 0 1 1 1 0 AAA domain Peptidase_S9 PF00326.21 KIK45591.1 - 4.1e-50 170.2 0.1 6.2e-50 169.6 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KIK45591.1 - 0.039 13.6 0.1 0.34 10.5 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2920 PF11144.8 KIK45591.1 - 0.17 11.0 0.0 1.6 7.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Ketoacyl-synt_C PF02801.22 KIK45592.1 - 0.00013 21.9 0.6 0.00018 21.5 0.6 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain CDC37_N PF03234.14 KIK45593.1 - 7.7e-43 146.5 0.6 1.6e-41 142.3 0.0 2.4 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KIK45593.1 - 1.4e-29 102.4 0.1 5.5e-29 100.5 0.0 1.9 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KIK45593.1 - 1.2e-18 67.1 0.5 1.2e-18 67.1 0.5 2.2 2 0 0 2 2 2 1 Cdc37 C terminal domain MepB PF08877.10 KIK45593.1 - 0.0082 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 MepB protein E2F_CC-MB PF16421.5 KIK45593.1 - 0.049 14.0 0.1 0.14 12.5 0.1 1.8 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain Adaptin_binding PF10199.9 KIK45596.1 - 1.4e-07 32.1 4.4 3.7e-06 27.5 4.4 2.6 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Lipase_3 PF01764.25 KIK45597.1 - 1e-23 83.8 0.0 1.4e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 KIK45597.1 - 0.00039 20.2 0.0 0.00059 19.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein UPF0227 PF05728.12 KIK45597.1 - 0.0059 16.6 0.0 0.0094 15.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_6 PF12697.7 KIK45597.1 - 0.0061 17.2 0.1 0.014 16.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 KIK45597.1 - 0.018 14.6 0.0 0.04 13.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 KIK45597.1 - 0.059 13.0 0.1 0.26 10.9 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.20 KIK45597.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain HEAT_2 PF13646.6 KIK45598.1 - 2.3e-37 127.2 6.7 1.4e-12 47.8 0.1 4.2 2 2 3 5 5 5 5 HEAT repeats HEAT_PBS PF03130.16 KIK45598.1 - 4.6e-21 73.3 0.2 0.00065 20.1 0.1 7.1 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.22 KIK45598.1 - 1.7e-13 49.5 4.0 0.0026 17.9 0.0 6.0 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 KIK45598.1 - 2.7e-05 24.6 3.1 3.4 8.3 0.5 4.9 3 1 1 4 4 4 2 HEAT-like repeat Arm PF00514.23 KIK45598.1 - 4.6e-05 23.3 0.3 0.026 14.5 0.1 3.2 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 KIK45598.1 - 0.0007 19.9 1.4 0.14 12.5 0.0 3.6 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 KIK45598.1 - 0.0017 18.4 0.0 0.09 12.8 0.0 3.2 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KIK45598.1 - 0.19 11.2 0.1 7.1 6.1 0.0 2.7 3 1 0 3 3 3 0 CLASP N terminal RL10P_insert PF17777.1 KIK45599.1 - 7.9e-22 77.0 0.0 1.3e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KIK45599.1 - 1.1e-19 70.4 0.0 1.6e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 RRF PF01765.19 KIK45599.1 - 0.13 12.2 0.2 0.21 11.6 0.2 1.4 1 0 0 1 1 1 0 Ribosome recycling factor Methyltransf_25 PF13649.6 KIK45601.1 - 1.7e-15 57.5 0.0 9.4e-15 55.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK45601.1 - 2.2e-12 47.4 0.0 7.2e-12 45.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK45601.1 - 9.9e-10 38.4 0.0 2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK45601.1 - 3.2e-09 36.9 0.0 6.5e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK45601.1 - 2.3e-07 30.4 0.0 4.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KIK45601.1 - 6.8e-06 26.7 0.0 2.4e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 KIK45601.1 - 4.3e-05 22.9 0.0 8.1e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain zf-CCHC PF00098.23 KIK45601.1 - 0.0077 16.3 0.7 0.015 15.3 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle MetW PF07021.12 KIK45601.1 - 0.0096 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 KIK45601.1 - 0.023 14.8 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.14 KIK45601.1 - 0.024 14.2 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 KIK45601.1 - 0.037 13.3 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 KIK45601.1 - 0.064 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MAPEG PF01124.18 KIK45601.1 - 0.22 11.4 0.0 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 MAPEG family zf-CCHC_4 PF14392.6 KIK45601.1 - 0.3 10.9 1.9 0.58 9.9 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle SRF-TF PF00319.18 KIK45602.1 - 9.3e-21 73.1 0.1 1.4e-20 72.5 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF4611 PF15387.6 KIK45602.1 - 4.6 7.5 7.0 2.3 8.5 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) zf-C3H1 PF10650.9 KIK45603.1 - 0.0046 16.6 2.3 0.0046 16.6 2.3 2.0 2 1 0 2 2 2 1 Putative zinc-finger domain VWA PF00092.28 KIK45606.1 - 1.5e-10 41.6 0.0 2.7e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIK45606.1 - 3.2e-06 27.7 0.0 8.5e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.8 KIK45606.1 - 0.00039 20.3 0.0 0.0007 19.5 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A EF_assoc_2 PF08356.12 KIK45607.1 - 3.5e-36 123.1 0.0 7.5e-36 122.0 0.0 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KIK45607.1 - 6e-32 110.5 0.0 3.9e-21 75.3 0.0 2.2 2 0 0 2 2 2 2 Ras family EF_assoc_1 PF08355.12 KIK45607.1 - 2.2e-29 100.8 1.0 5.1e-29 99.7 1.0 1.6 1 0 0 1 1 1 1 EF hand associated Roc PF08477.13 KIK45607.1 - 1.1e-17 64.4 0.0 1.8e-09 37.9 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 KIK45607.1 - 1.5e-10 39.9 1.9 0.00046 19.5 0.5 2.8 2 0 0 2 2 2 2 EF hand Arf PF00025.21 KIK45607.1 - 5.2e-10 39.1 0.0 8.9e-05 22.0 0.0 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family EF-hand_6 PF13405.6 KIK45607.1 - 6e-10 38.2 0.3 0.00043 20.0 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KIK45607.1 - 1.9e-09 37.8 0.5 0.00096 19.6 0.1 3.3 3 1 0 3 3 3 2 EF-hand domain pair MMR_HSR1 PF01926.23 KIK45607.1 - 6.9e-08 32.6 0.1 0.0013 18.8 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KIK45607.1 - 7.9e-08 32.7 0.0 0.011 16.0 0.0 3.1 3 1 0 3 3 2 2 AAA domain EF-hand_5 PF13202.6 KIK45607.1 - 1.2e-07 30.9 3.9 0.0096 15.4 0.1 2.8 2 0 0 2 2 2 2 EF hand AAA_16 PF13191.6 KIK45607.1 - 2.3e-06 28.1 0.0 0.12 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIK45607.1 - 3.7e-05 23.7 0.1 0.27 11.1 0.0 3.8 4 0 0 4 4 4 1 RsgA GTPase NACHT PF05729.12 KIK45607.1 - 4.3e-05 23.5 0.0 0.22 11.4 0.0 2.9 3 0 0 3 3 2 2 NACHT domain AAA_24 PF13479.6 KIK45607.1 - 5.8e-05 22.9 0.0 0.28 10.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KIK45607.1 - 8.2e-05 23.2 0.0 0.045 14.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain EF-hand_10 PF14788.6 KIK45607.1 - 0.00013 21.7 1.0 0.042 13.7 0.1 2.5 2 0 0 2 2 2 1 EF hand ABC_tran PF00005.27 KIK45607.1 - 0.00015 22.2 0.0 0.33 11.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter Dynamin_N PF00350.23 KIK45607.1 - 0.00022 21.3 1.2 2.9 7.9 0.0 3.5 2 1 1 3 3 3 1 Dynamin family AAA_33 PF13671.6 KIK45607.1 - 0.00022 21.4 0.3 0.73 10.0 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_29 PF13555.6 KIK45607.1 - 0.00024 20.8 0.0 0.069 12.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 KIK45607.1 - 0.00025 21.5 0.0 0.23 11.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 KIK45607.1 - 0.00034 20.0 0.0 0.082 12.2 0.0 2.3 2 0 0 2 2 2 1 Septin RNA_helicase PF00910.22 KIK45607.1 - 0.00035 20.9 0.0 0.29 11.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 KIK45607.1 - 0.00047 20.4 0.0 0.74 10.0 0.0 2.7 2 1 0 2 2 2 2 AAA domain PduV-EutP PF10662.9 KIK45607.1 - 0.0007 19.4 0.0 0.083 12.6 0.0 2.6 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KIK45607.1 - 0.0007 19.5 1.5 4.9 6.9 0.0 4.1 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 KIK45607.1 - 0.0007 19.2 0.0 0.13 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KIK45607.1 - 0.00072 19.1 0.0 0.067 12.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region SRPRB PF09439.10 KIK45607.1 - 0.0014 18.1 0.0 2 7.8 0.0 2.5 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KIK45607.1 - 0.003 16.8 0.0 1.7 7.7 0.0 2.6 3 0 0 3 3 3 1 G-protein alpha subunit NB-ARC PF00931.22 KIK45607.1 - 0.0042 16.3 0.1 2.1 7.5 0.0 3.0 2 1 1 3 3 3 1 NB-ARC domain AAA_5 PF07728.14 KIK45607.1 - 0.0047 16.9 0.0 0.21 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) VirE PF05272.11 KIK45607.1 - 0.0049 16.6 0.1 2.8 7.6 0.0 3.2 3 1 0 3 3 3 1 Virulence-associated protein E Ploopntkinase3 PF18751.1 KIK45607.1 - 0.005 16.8 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 DUF815 PF05673.13 KIK45607.1 - 0.0064 15.7 0.0 0.31 10.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 KIK45607.1 - 0.0065 16.2 0.0 0.26 11.0 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase SPARC_Ca_bdg PF10591.9 KIK45607.1 - 0.02 15.2 2.0 1.9 8.8 0.0 2.8 3 0 0 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region TsaE PF02367.17 KIK45607.1 - 0.02 14.9 0.0 3 7.8 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NOG1 PF06858.14 KIK45607.1 - 0.022 14.5 0.2 2.5 7.9 0.1 2.9 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) MCM PF00493.23 KIK45607.1 - 0.026 13.6 0.0 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 KIK45607.1 - 0.027 13.8 0.1 6.2 6.1 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family TniB PF05621.11 KIK45607.1 - 0.029 13.8 0.0 8.5 5.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein ATPase_2 PF01637.18 KIK45607.1 - 0.038 13.9 0.4 2.7 7.8 0.0 3.2 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea AIG1 PF04548.16 KIK45607.1 - 0.042 13.2 0.1 0.089 12.1 0.0 1.6 2 0 0 2 2 1 0 AIG1 family Pox_A32 PF04665.12 KIK45607.1 - 0.05 13.1 0.0 5 6.5 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein cobW PF02492.19 KIK45607.1 - 0.061 12.9 0.2 3.1 7.4 0.0 3.1 3 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KIK45607.1 - 0.069 12.9 0.0 4.1 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain EF-hand_8 PF13833.6 KIK45607.1 - 0.08 12.8 0.8 8.2 6.4 0.2 3.3 3 0 0 3 3 3 0 EF-hand domain pair Zeta_toxin PF06414.12 KIK45607.1 - 0.093 12.0 0.0 9 5.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 KIK45607.1 - 0.22 12.0 0.1 38 4.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain F-box PF00646.33 KIK45608.1 - 0.00053 19.8 0.4 0.00053 19.8 0.4 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIK45608.1 - 0.012 15.5 1.2 0.07 13.0 0.1 2.4 2 0 0 2 2 2 0 F-box-like RasGEF PF00617.19 KIK45609.1 - 1e-47 162.6 0.0 2.5e-47 161.3 0.0 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KIK45609.1 - 3.9e-21 75.3 0.1 1.1e-20 73.8 0.1 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 KIK45609.1 - 2.8e-13 49.5 0.0 5.4e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIK45609.1 - 1.2e-12 47.2 0.0 3.1e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KIK45609.1 - 1.5e-12 47.0 0.0 2.9e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3851 PF12962.7 KIK45609.1 - 0.084 13.2 0.1 0.9 9.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3851) CHAT PF12770.7 KIK45612.1 - 7e-40 137.2 0.0 1.6e-39 136.0 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK45612.1 - 2e-33 113.3 45.9 0.026 14.4 0.1 19.7 19 0 0 19 19 19 13 Tetratricopeptide repeat TPR_12 PF13424.6 KIK45612.1 - 4.6e-11 42.9 73.6 2.1 8.7 0.2 20.5 8 6 14 22 22 22 5 Tetratricopeptide repeat TPR_7 PF13176.6 KIK45612.1 - 2.2e-08 33.5 18.3 7.8 6.8 0.0 12.6 16 0 0 16 16 14 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIK45612.1 - 9.2e-08 31.7 7.0 87 3.7 0.0 12.1 15 0 0 15 15 15 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK45612.1 - 0.00012 21.6 34.4 2 8.2 0.0 12.1 16 0 0 16 16 16 4 TPR repeat T3SS_ATPase_C PF18269.1 KIK45612.1 - 0.00017 21.4 21.4 45 4.0 0.0 12.1 13 0 0 13 13 13 0 T3SS EscN ATPase C-terminal domain TPR_2 PF07719.17 KIK45612.1 - 0.0014 18.5 58.0 1.3 9.3 0.1 17.0 20 0 0 20 20 19 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK45612.1 - 0.0016 18.7 7.8 7.5 7.2 0.0 9.1 10 1 1 11 11 9 1 Tetratricopeptide repeat DUF4471 PF14740.6 KIK45612.1 - 0.0024 17.1 13.2 3.3 6.9 0.0 7.1 5 2 2 7 7 7 2 Domain of unknown function (DUF4471) TPR_14 PF13428.6 KIK45612.1 - 0.0076 17.0 52.6 5.2 8.1 0.1 15.8 19 1 1 20 20 16 3 Tetratricopeptide repeat Phage_fiber_2 PF03406.13 KIK45612.1 - 0.017 14.7 0.1 30 4.3 0.0 4.7 4 0 0 4 4 4 0 Phage tail fibre repeat TPR_1 PF00515.28 KIK45612.1 - 0.1 12.5 36.1 0.76 9.7 0.0 11.8 13 0 0 13 13 13 0 Tetratricopeptide repeat MBOAT_2 PF13813.6 KIK45614.1 - 5.9e-13 48.9 4.6 5.9e-13 48.9 4.6 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family NCA2 PF08637.10 KIK45615.1 - 1.3e-77 260.8 0.0 2e-77 260.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Mod_r PF07200.13 KIK45616.1 - 2.4e-46 157.4 3.9 2.8e-46 157.2 3.9 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein HMMR_N PF15905.5 KIK45616.1 - 0.03 13.8 0.5 0.036 13.5 0.5 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal GCN5L1 PF06320.13 KIK45616.1 - 0.081 13.1 0.7 0.18 11.9 0.7 1.6 1 1 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Rootletin PF15035.6 KIK45616.1 - 0.086 12.9 6.0 0.13 12.2 4.7 1.8 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF4200 PF13863.6 KIK45616.1 - 0.5 10.8 6.4 0.12 12.8 3.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) ZapB PF06005.12 KIK45616.1 - 0.61 10.6 4.7 0.7 10.4 3.5 1.7 1 1 1 2 2 2 0 Cell division protein ZapB Rrp40_N PF18311.1 KIK45617.1 - 3.6e-14 52.4 0.3 7.4e-14 51.4 0.3 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 KIK45617.1 - 1.5e-10 41.3 0.0 2.5e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 KH domain NuA4 PF09340.10 KIK45618.1 - 1.2e-23 82.7 0.2 4e-23 81.1 0.0 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 HJURP_C PF12347.8 KIK45618.1 - 0.075 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat AAA PF00004.29 KIK45620.1 - 1.1e-40 139.1 0.0 1.9e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KIK45620.1 - 8.8e-21 73.6 0.2 1.8e-20 72.6 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KIK45620.1 - 1.1e-10 41.2 0.1 2.4e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KIK45620.1 - 6.3e-05 23.4 0.3 0.012 16.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KIK45620.1 - 0.00052 20.0 0.3 0.0057 16.6 0.3 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIK45620.1 - 0.00085 19.5 0.1 0.012 15.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KIK45620.1 - 0.00099 19.4 0.7 0.11 12.8 0.1 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KIK45620.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain PhoH PF02562.16 KIK45620.1 - 0.0044 16.5 0.1 0.053 13.0 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.6 KIK45620.1 - 0.0059 16.8 0.1 0.013 15.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KIK45620.1 - 0.018 14.4 0.0 0.042 13.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KIK45620.1 - 0.027 14.2 0.1 0.056 13.2 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 KIK45620.1 - 0.039 13.7 0.1 0.41 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KIK45620.1 - 0.078 12.7 0.1 0.21 11.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 KIK45620.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) XhlA PF10779.9 KIK45620.1 - 4.7 7.5 5.5 73 3.7 3.5 2.5 2 0 0 2 2 2 0 Haemolysin XhlA ABC_membrane PF00664.23 KIK45621.1 - 7.9e-103 343.9 32.1 5.1e-52 177.2 12.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK45621.1 - 3.5e-69 231.6 0.0 3.2e-34 118.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIK45621.1 - 4.6e-14 52.4 2.1 5.2e-05 22.8 0.1 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIK45621.1 - 3.4e-07 30.8 1.8 0.005 17.2 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 KIK45621.1 - 4.2e-07 29.1 1.2 0.0021 16.9 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 KIK45621.1 - 5.5e-07 29.2 0.3 0.013 15.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KIK45621.1 - 8.7e-07 29.0 0.6 0.081 12.7 0.0 3.9 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIK45621.1 - 2.7e-06 27.3 0.1 0.074 12.7 0.1 2.3 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KIK45621.1 - 6.8e-06 25.5 0.0 0.019 14.2 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.6 KIK45621.1 - 1.2e-05 25.6 0.6 0.17 12.2 0.1 3.7 3 1 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 KIK45621.1 - 2.9e-05 24.0 0.1 0.28 11.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 KIK45621.1 - 0.00012 21.4 0.0 0.4 9.8 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_30 PF13604.6 KIK45621.1 - 0.00013 21.8 0.0 2 8.1 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 KIK45621.1 - 0.00013 21.7 0.6 0.29 10.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 KIK45621.1 - 0.00018 22.0 0.3 2 8.8 0.2 3.8 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIK45621.1 - 0.00043 20.3 0.0 1.3 9.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KIK45621.1 - 0.0008 20.0 0.1 0.81 10.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KIK45621.1 - 0.0019 18.7 0.0 1.3 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KIK45621.1 - 0.0031 17.9 0.1 5.1 7.5 0.0 4.0 4 0 0 4 4 4 1 RNA helicase AAA_28 PF13521.6 KIK45621.1 - 0.0041 17.4 0.0 1.4 9.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KIK45621.1 - 0.0061 16.8 3.2 4.3 7.7 0.2 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 KIK45621.1 - 0.0079 15.4 0.1 0.73 9.0 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain APS_kinase PF01583.20 KIK45621.1 - 0.0086 16.0 0.0 2.5 8.0 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_33 PF13671.6 KIK45621.1 - 0.012 15.7 0.0 7.1 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 KIK45621.1 - 0.013 15.2 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_7 PF12775.7 KIK45621.1 - 0.014 14.9 0.0 3.5 7.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 KIK45621.1 - 0.018 15.2 0.3 3 7.9 0.1 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 KIK45621.1 - 0.03 14.4 0.1 9.2 6.4 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF815 PF05673.13 KIK45621.1 - 0.036 13.2 0.0 8.2 5.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KIK45621.1 - 0.13 11.9 0.0 15 5.2 0.0 2.6 3 0 0 3 3 2 0 AAA domain Rad17 PF03215.15 KIK45621.1 - 0.14 12.1 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_17 PF13207.6 KIK45621.1 - 0.14 12.5 0.0 29 5.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 KIK45622.1 - 7.2e-71 238.6 0.0 9e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK45622.1 - 3.3e-32 111.8 0.0 4.5e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KIK45622.1 - 1e-11 45.3 0.9 1e-11 45.3 0.9 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KIK45622.1 - 1.1e-07 31.2 0.1 1.5e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KIK45622.1 - 8.8e-05 22.0 0.0 0.00021 20.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KIK45622.1 - 0.011 15.4 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIK45622.1 - 0.03 13.7 0.1 0.048 13.0 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK45622.1 - 0.057 13.3 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIK45622.1 - 0.16 11.5 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase G-patch PF01585.23 KIK45623.1 - 4.4e-08 32.9 0.2 2.2e-06 27.4 0.3 2.3 2 0 0 2 2 2 2 G-patch domain F-box-like PF12937.7 KIK45624.1 - 8.9e-11 41.5 0.2 3.3e-10 39.7 0.2 2.1 1 0 0 1 1 1 1 F-box-like CM_2 PF01817.21 KIK45624.1 - 0.21 12.0 0.1 0.42 11.0 0.1 1.5 1 0 0 1 1 1 0 Chorismate mutase type II PQ-loop PF04193.14 KIK45625.1 - 3.3e-13 49.2 0.2 1.5e-12 47.0 0.0 2.1 2 0 0 2 2 2 1 PQ loop repeat Band_7 PF01145.25 KIK45626.1 - 2.4e-22 79.8 2.5 3.3e-22 79.4 2.5 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family MutS_V PF00488.21 KIK45627.1 - 4.5e-43 147.5 0.1 5.6e-42 143.9 0.1 2.1 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KIK45627.1 - 6.5e-32 111.3 0.0 1.5e-31 110.2 0.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 KIK45627.1 - 0.017 15.4 0.0 0.047 14.0 0.0 1.7 1 0 0 1 1 1 0 MutS family domain IV Mito_carr PF00153.27 KIK45628.1 - 4.3e-39 132.3 3.4 7.5e-17 61.0 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein ABM PF03992.16 KIK45629.1 - 0.00041 20.4 0.0 0.013 15.6 0.0 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase ABM PF03992.16 KIK45632.1 - 0.071 13.2 0.3 0.22 11.7 0.2 1.8 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Motile_Sperm PF00635.26 KIK45633.1 - 8.1e-27 93.2 0.4 1.5e-26 92.3 0.4 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 KIK45633.1 - 0.0068 16.6 0.1 0.014 15.6 0.1 1.5 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin FixG_C PF11614.8 KIK45633.1 - 0.048 13.9 0.0 0.079 13.2 0.0 1.3 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Sod_Cu PF00080.20 KIK45634.1 - 1.7e-47 161.1 1.3 2.4e-47 160.7 1.1 1.3 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) RSN1_7TM PF02714.15 KIK45635.1 - 9.9e-42 143.1 23.4 2e-41 142.1 23.4 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KIK45635.1 - 1.9e-22 80.3 0.0 3.8e-16 59.8 0.0 2.9 2 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KIK45635.1 - 2.4e-16 59.9 0.3 2.4e-16 59.9 0.3 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport ETC_C1_NDUFA4 PF04800.12 KIK45636.1 - 1.4e-36 124.6 0.6 2e-36 124.1 0.6 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region MFS_1 PF07690.16 KIK45637.1 - 2.7e-22 79.2 36.9 2.7e-22 79.2 36.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK45637.1 - 2.5e-08 33.2 14.7 4.3e-08 32.5 14.7 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KIK45637.1 - 1.9e-06 26.6 1.4 3.7e-06 25.7 1.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FMO-like PF00743.19 KIK45638.1 - 7.1e-18 64.3 0.8 3.2e-17 62.1 0.1 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KIK45638.1 - 1.9e-09 37.6 0.1 4.9e-09 36.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIK45638.1 - 7.7e-08 31.9 1.0 3.8e-07 29.7 0.2 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK45638.1 - 9.3e-08 31.6 0.3 1.7e-06 27.4 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KIK45638.1 - 3.1e-07 29.9 0.0 5.7e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK45638.1 - 0.0056 16.3 1.1 0.022 14.3 0.6 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIK45638.1 - 0.069 13.1 0.0 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KIK45638.1 - 0.087 11.9 0.2 0.13 11.3 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KIK45638.1 - 0.2 10.9 0.4 1.3 8.2 0.1 2.3 3 0 0 3 3 3 0 Thi4 family GIDA PF01134.22 KIK45638.1 - 0.49 9.4 1.0 4.9 6.1 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A RICTOR_N PF14664.6 KIK45639.1 - 2.9e-120 401.7 0.1 5e-120 400.9 0.1 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 KIK45639.1 - 4.9e-40 135.5 0.8 8.5e-36 121.9 0.1 4.0 2 1 2 4 4 4 2 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 KIK45639.1 - 7.2e-36 122.9 0.0 3.3e-34 117.5 0.0 2.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 KIK45639.1 - 5e-30 103.5 0.4 6.9e-27 93.5 0.0 4.8 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KIK45639.1 - 5.3e-06 26.5 3.0 1.4e-05 25.1 3.0 1.7 1 0 0 1 1 1 1 Hr1 repeat CheX PF13690.6 KIK45639.1 - 0.015 15.5 0.0 7.7 6.8 0.0 3.0 2 0 0 2 2 2 0 Chemotaxis phosphatase CheX WD40 PF00400.32 KIK45640.1 - 1.9e-05 25.3 10.0 0.0002 22.1 0.5 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.8 KIK45640.1 - 0.00085 18.1 0.8 0.1 11.2 0.1 2.0 2 0 0 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KIK45640.1 - 0.0016 18.7 0.1 0.0079 16.5 0.1 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK45640.1 - 0.011 14.7 0.0 1.6 7.6 0.0 2.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Oxysterol_BP PF01237.18 KIK45641.1 - 2.4e-55 187.9 1.0 3.5e-48 164.3 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein UQ_con PF00179.26 KIK45642.1 - 1.3e-49 167.5 0.0 1.5e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RNA_pol_Rpb2_6 PF00562.28 KIK45647.1 - 1.3e-107 360.2 0.1 2e-107 359.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KIK45647.1 - 5.1e-56 189.4 0.0 8.4e-56 188.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KIK45647.1 - 2.6e-32 111.1 0.3 6.9e-32 109.7 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KIK45647.1 - 3.2e-28 98.7 0.0 7.2e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KIK45647.1 - 7.6e-24 83.8 3.0 1.3e-23 83.0 1.9 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KIK45647.1 - 1.4e-20 73.3 0.1 5.4e-20 71.3 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KIK45647.1 - 7.7e-12 45.6 0.3 2.2e-11 44.1 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Elicitin PF00964.17 KIK45648.1 - 0.1 12.7 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Elicitin UQ_con PF00179.26 KIK45649.1 - 1.1e-44 151.5 0.0 1.2e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIK45649.1 - 0.13 11.9 0.0 0.44 10.2 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B ALO PF04030.14 KIK45650.1 - 1.9e-78 263.9 0.4 2.3e-78 263.6 0.4 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KIK45650.1 - 1.7e-27 95.9 0.3 3.1e-27 95.0 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain HSP70 PF00012.20 KIK45651.1 - 0.0017 16.6 0.0 0.0054 15.0 0.0 1.7 2 1 0 2 2 2 1 Hsp70 protein BcrAD_BadFG PF01869.20 KIK45651.1 - 0.043 13.3 0.1 0.079 12.4 0.1 1.4 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family BMFP PF04380.13 KIK45651.1 - 0.065 13.7 0.1 0.12 12.9 0.1 1.4 1 0 0 1 1 1 0 Membrane fusogenic activity Noc2 PF03715.13 KIK45654.1 - 5.9e-109 363.9 0.0 2.4e-108 361.9 0.0 2.0 3 0 0 3 3 3 1 Noc2p family DUF1776 PF08643.10 KIK45654.1 - 0.0054 16.1 0.6 0.9 8.9 0.7 2.2 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) MT-A70 PF05063.14 KIK45655.1 - 7.6e-40 136.6 0.0 1.8e-39 135.4 0.0 1.6 1 1 0 1 1 1 1 MT-A70 Kelch_4 PF13418.6 KIK45657.1 - 3.3e-35 119.9 20.2 2.8e-06 27.2 0.1 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 KIK45657.1 - 4.4e-34 115.8 17.7 1.2e-07 31.2 0.4 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 KIK45657.1 - 2.4e-31 107.2 11.3 7e-09 35.5 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KIK45657.1 - 1.1e-24 85.4 22.4 6.7e-05 22.7 0.2 7.3 7 0 0 7 7 7 6 Kelch motif Kelch_3 PF13415.6 KIK45657.1 - 1.7e-23 82.3 32.7 4.1e-06 26.9 0.1 8.3 7 2 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.6 KIK45657.1 - 2e-22 78.7 19.8 3.3e-06 27.2 0.1 6.8 4 2 2 6 6 6 6 Kelch motif DUF3421 PF11901.8 KIK45659.1 - 3.4e-23 81.8 0.0 9.3e-12 45.0 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) VWA PF00092.28 KIK45659.1 - 2.9e-06 27.6 0.0 5.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 KIK45659.1 - 0.0052 16.9 0.1 0.0091 16.1 0.1 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.6 KIK45659.1 - 0.0083 16.8 0.0 0.028 15.1 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain DUF3421 PF11901.8 KIK45661.1 - 6e-08 32.7 0.0 7.4e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3421) SPX PF03105.19 KIK45664.1 - 0.12 12.3 3.7 0.15 11.9 3.7 1.1 1 0 0 1 1 1 0 SPX domain PEN-2 PF10251.9 KIK45665.1 - 0.15 12.5 0.9 0.2 12.1 0.3 1.6 1 1 1 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase SSF PF00474.17 KIK45666.1 - 4.2e-16 58.8 15.4 4.2e-16 58.8 15.4 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family FAD_binding_3 PF01494.19 KIK45668.1 - 3e-28 99.1 0.0 4.1e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK45668.1 - 5.1e-10 39.1 0.3 7.9e-05 22.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK45668.1 - 2.9e-06 27.4 0.0 6.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK45668.1 - 4.8e-06 26.4 4.7 0.028 14.0 0.1 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIK45668.1 - 9.3e-06 26.1 0.0 0.12 12.9 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIK45668.1 - 0.024 13.5 0.3 1.9 7.2 0.1 2.6 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_2 PF00890.24 KIK45668.1 - 0.03 13.4 0.2 0.064 12.3 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain SE PF08491.10 KIK45668.1 - 0.045 12.8 0.0 7.4 5.5 0.0 2.3 2 1 0 2 2 2 0 Squalene epoxidase Pyr_redox_3 PF13738.6 KIK45668.1 - 0.097 11.9 0.1 12 5.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_30 PF02055.16 KIK45672.1 - 2.6e-25 89.1 1.0 3.6e-25 88.7 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 KIK45672.1 - 1.3e-13 50.8 0.3 2.3e-13 50.0 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 KIK45672.1 - 0.0017 18.0 0.0 0.39 10.3 0.0 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Adaptin_N PF01602.20 KIK45675.1 - 1.8e-139 465.7 8.5 2.3e-139 465.3 8.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KIK45675.1 - 9.2e-60 201.4 4.4 1.8e-58 197.2 0.8 3.0 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIK45675.1 - 2.9e-17 62.8 3.6 7.6e-08 32.7 0.2 6.1 2 2 4 6 6 6 5 HEAT repeats HEAT PF02985.22 KIK45675.1 - 1e-08 34.7 8.9 0.0016 18.5 0.1 5.7 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 KIK45675.1 - 2.4e-07 31.1 1.6 2.3 8.8 0.1 6.0 6 0 0 6 6 6 2 HEAT-like repeat Cnd3 PF12719.7 KIK45675.1 - 6.8e-05 22.2 0.2 0.093 11.9 0.1 2.5 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 KIK45675.1 - 9.8e-05 22.3 4.3 0.075 13.1 0.0 5.2 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KIK45675.1 - 0.00082 19.5 1.0 0.99 9.6 0.0 3.9 2 2 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 TIP120 PF08623.10 KIK45675.1 - 0.0062 16.3 2.1 0.46 10.2 0.0 3.4 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) CLASP_N PF12348.8 KIK45675.1 - 0.029 14.0 0.2 6 6.3 0.0 3.2 2 1 1 3 3 3 0 CLASP N terminal Sec7_N PF12783.7 KIK45675.1 - 0.077 12.9 1.9 0.41 10.5 0.1 2.7 1 1 1 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Phage_holin_3_6 PF07332.11 KIK45677.1 - 4.6 7.3 6.6 0.27 11.3 0.6 1.9 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III WD40 PF00400.32 KIK45679.1 - 1.1e-39 133.7 33.6 9.3e-07 29.5 1.6 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45679.1 - 6e-20 71.3 4.6 1.4e-05 25.3 0.1 5.3 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain HemolysinCabind PF00353.19 KIK45679.1 - 1.4e-15 56.9 0.1 0.15 12.1 0.2 8.7 5 2 3 9 9 9 4 RTX calcium-binding nonapeptide repeat (4 copies) Ge1_WD40 PF16529.5 KIK45679.1 - 1.2e-06 27.8 1.3 0.038 13.0 0.0 4.6 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK45679.1 - 8.4e-05 21.4 7.5 0.81 8.3 0.0 4.4 2 2 1 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK45679.1 - 0.0015 17.9 0.0 0.17 11.2 0.0 2.5 1 1 1 2 2 2 2 WD40-like domain Nbas_N PF15492.6 KIK45679.1 - 0.0045 16.4 0.3 2.3 7.4 0.0 2.7 2 1 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal PUL PF08324.11 KIK45680.1 - 1.4e-21 77.0 0.0 2.3e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.20 KIK45680.1 - 1.9e-05 24.6 0.0 3.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin NB-ARC PF00931.22 KIK45681.1 - 3.7e-06 26.3 0.0 5.4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 KIK45681.1 - 1.9e-05 25.1 0.0 4.8e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK45681.1 - 0.0004 20.7 0.0 0.002 18.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KIK45681.1 - 0.0019 18.2 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK45681.1 - 0.0048 17.3 0.9 0.013 15.9 0.1 1.9 2 1 0 2 2 2 1 AAA ATPase domain Arg_repressor_C PF02863.18 KIK45681.1 - 0.041 13.7 1.1 1.1 9.1 0.3 2.4 1 1 1 2 2 2 0 Arginine repressor, C-terminal domain SUR7 PF06687.12 KIK45683.1 - 9e-11 41.8 22.0 1.5e-10 41.1 20.8 1.9 1 1 1 2 2 2 1 SUR7/PalI family Trp_oprn_chp PF09534.10 KIK45683.1 - 0.0016 18.2 2.2 0.0023 17.7 2.2 1.2 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SLATT_1 PF18181.1 KIK45683.1 - 0.39 10.7 3.0 0.75 9.7 3.0 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 UPF0182 PF03699.13 KIK45683.1 - 0.76 7.8 4.4 0.92 7.6 4.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Amastin PF07344.11 KIK45683.1 - 1.5 8.7 12.2 3.3 7.5 12.0 1.9 1 1 0 1 1 1 0 Amastin surface glycoprotein zf-RING_2 PF13639.6 KIK45685.1 - 4.6e-09 36.5 7.9 8.8e-09 35.6 7.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KIK45685.1 - 2.2e-08 33.9 6.6 3.5e-08 33.3 6.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIK45685.1 - 1.5e-07 31.4 6.4 3.8e-06 26.8 2.8 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KIK45685.1 - 1.7e-07 31.0 8.5 5.9e-07 29.3 8.3 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KIK45685.1 - 1.7e-07 31.0 4.4 3.2e-07 30.1 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK45685.1 - 7.1e-07 29.0 7.5 1.3e-06 28.1 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK45685.1 - 1.2e-05 25.1 6.7 2.8e-05 23.9 6.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK45685.1 - 0.00013 22.0 8.3 0.0032 17.6 8.7 2.8 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KIK45685.1 - 0.00047 19.9 4.9 0.00084 19.1 4.9 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Rtf2 PF04641.12 KIK45685.1 - 0.012 15.0 0.3 0.012 15.0 0.3 1.9 2 1 0 2 2 2 0 Rtf2 RING-finger zf-rbx1 PF12678.7 KIK45685.1 - 0.014 15.7 5.2 0.014 15.7 5.2 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain Rad50_zn_hook PF04423.14 KIK45685.1 - 0.02 14.7 0.3 0.081 12.8 0.3 2.0 1 0 0 1 1 1 0 Rad50 zinc hook motif Phostensin_N PF13916.6 KIK45685.1 - 0.03 14.6 1.3 7.1 7.0 0.0 2.2 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal zf-RING_11 PF17123.5 KIK45685.1 - 0.032 14.0 3.5 0.085 12.6 3.5 1.8 1 0 0 1 1 1 0 RING-like zinc finger FYVE PF01363.21 KIK45685.1 - 0.068 13.3 3.8 0.29 11.3 3.9 1.9 1 1 0 1 1 1 0 FYVE zinc finger PDEase_I_N PF08499.12 KIK45685.1 - 0.069 13.0 0.3 0.2 11.5 0.3 1.7 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal FUSC PF04632.12 KIK45685.1 - 0.26 9.8 1.2 0.33 9.4 1.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-CXXC PF02008.20 KIK45685.1 - 8.8 6.4 7.4 1.1 9.4 0.7 2.4 2 1 1 3 3 3 0 CXXC zinc finger domain RRM_1 PF00076.22 KIK45689.1 - 1.8e-29 101.4 0.3 4.4e-15 55.2 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK45689.1 - 0.00032 20.8 0.0 0.0037 17.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif RRM_3 PF08777.11 KIK45689.1 - 0.0017 18.3 0.0 2.1 8.5 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 KIK45689.1 - 0.042 13.9 0.0 0.5 10.4 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KIK45689.1 - 0.043 14.0 0.0 0.1 12.8 0.0 1.9 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 KIK45689.1 - 0.051 13.4 0.0 2.9 7.7 0.0 2.7 1 1 0 1 1 1 0 Rrp7 RRM-like N-terminal domain DNA_ligase_IV PF11411.8 KIK45689.1 - 0.11 12.7 0.1 20 5.4 0.0 2.4 2 0 0 2 2 2 0 DNA ligase IV UQ_con PF00179.26 KIK45690.1 - 8.1e-39 132.5 0.0 1.2e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ammonium_transp PF00909.21 KIK45690.1 - 0.026 13.3 0.2 0.035 12.8 0.2 1.1 1 0 0 1 1 1 0 Ammonium Transporter Family DUF4131 PF13567.6 KIK45691.1 - 0.26 10.9 2.0 0.55 9.9 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) ABC1 PF03109.16 KIK45693.1 - 8.6e-26 90.4 0.0 1.5e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 KIK45693.1 - 0.0044 16.4 0.0 0.0069 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF269 PF03270.13 KIK45696.1 - 0.055 13.6 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF269 WD40 PF00400.32 KIK45699.1 - 2.3e-48 161.1 27.7 1.7e-08 34.9 0.6 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45699.1 - 3.8e-19 68.8 3.9 0.0015 18.8 0.2 5.7 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK45699.1 - 2e-08 33.3 4.4 0.0016 17.2 0.5 4.5 3 2 2 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK45699.1 - 4.2e-08 32.5 0.7 0.12 11.3 0.0 5.6 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KIK45699.1 - 1.5e-06 27.2 1.0 0.006 15.4 0.0 3.6 2 2 2 4 4 4 2 Nup133 N terminal like WD40_like PF17005.5 KIK45699.1 - 0.0012 18.2 0.0 1.1 8.5 0.0 3.3 2 1 2 4 4 4 2 WD40-like domain PD40 PF07676.12 KIK45699.1 - 0.0059 16.5 0.2 21 5.2 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIK45699.1 - 0.0067 15.8 0.5 1.6 8.0 0.1 3.5 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal DUF5570 PF17731.1 KIK45699.1 - 0.057 13.5 1.2 6 7.0 0.0 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5570) PALB2_WD40 PF16756.5 KIK45699.1 - 0.14 11.0 7.6 3.9 6.3 0.0 3.3 3 1 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain PAP2 PF01569.21 KIK45701.1 - 4.3e-28 97.8 2.3 6.8e-28 97.1 2.3 1.3 1 0 0 1 1 1 1 PAP2 superfamily DUF5510 PF17629.2 KIK45701.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5510) FtsK_4TM PF13491.6 KIK45703.1 - 0.033 13.9 0.3 0.033 13.9 0.3 2.2 2 0 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE RCC1 PF00415.18 KIK45705.1 - 1.8e-16 60.5 5.4 0.0011 19.5 0.1 6.1 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KIK45705.1 - 3.7e-12 46.5 0.0 4.4e-05 23.7 0.0 2.7 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 KIK45705.1 - 5.3e-10 39.6 0.2 1.3e-09 38.4 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) RCC1_2 PF13540.6 KIK45705.1 - 1.5e-08 34.2 16.1 4.2e-08 32.8 0.0 6.0 7 0 0 7 7 7 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.6 KIK45705.1 - 1.2e-07 31.4 0.3 0.007 16.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KIK45705.1 - 5.2e-07 30.2 0.1 1.1e-06 29.1 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIK45705.1 - 6.8e-07 29.4 0.6 3.1e-05 24.2 0.1 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KIK45705.1 - 0.0021 18.4 6.4 0.071 13.6 0.1 3.9 3 0 0 3 3 3 1 Ankyrin repeat EKLF_TAD1 PF16832.5 KIK45705.1 - 0.12 12.3 0.3 0.33 10.8 0.3 1.7 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 BAR PF03114.18 KIK45705.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 BAR domain PHD PF00628.29 KIK45706.1 - 9.8e-08 31.8 10.0 1.3e-07 31.4 10.0 1.2 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KIK45706.1 - 0.0089 15.6 7.9 0.015 14.9 7.9 1.3 1 0 0 1 1 1 1 PHD-finger DEC-1_N PF04625.13 KIK45706.1 - 1 8.3 4.3 1 8.3 4.3 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region C1_1 PF00130.22 KIK45706.1 - 5.5 7.0 10.4 0.099 12.5 3.3 1.7 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MFS_1 PF07690.16 KIK45709.1 - 8e-30 104.0 27.8 1.1e-29 103.5 27.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KIK45709.1 - 0.0013 18.1 5.0 0.0013 18.1 5.0 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Pex24p PF06398.11 KIK45709.1 - 0.066 12.2 1.6 0.71 8.8 0.8 2.3 1 1 0 2 2 2 0 Integral peroxisomal membrane peroxin Wzz PF02706.15 KIK45709.1 - 0.076 13.3 0.2 0.24 11.7 0.2 1.9 1 0 0 1 1 1 0 Chain length determinant protein PMSR PF01625.21 KIK45711.1 - 2.8e-61 206.2 2.1 2.8e-61 206.2 2.1 1.4 2 0 0 2 2 2 1 Peptide methionine sulfoxide reductase OPT PF03169.15 KIK45712.1 - 3.4e-88 296.8 42.0 5.8e-88 296.1 42.0 1.3 1 1 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.15 KIK45713.1 - 5.3e-81 273.1 37.2 7.9e-81 272.5 37.2 1.3 1 1 0 1 1 1 1 OPT oligopeptide transporter protein UCR_hinge PF02320.16 KIK45715.1 - 7e-21 74.2 5.0 1.3e-20 73.4 5.0 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein WD40 PF00400.32 KIK45716.1 - 1.4e-15 57.4 2.3 4.5e-08 33.6 0.1 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45716.1 - 2.5e-06 27.7 0.1 0.18 12.2 0.0 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK45716.1 - 0.001 18.1 0.0 0.076 12.0 0.0 2.1 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK45716.1 - 0.0097 15.8 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK45716.1 - 0.066 11.8 0.1 0.07 11.8 0.1 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Pex14_N PF04695.13 KIK45717.1 - 9.3 6.9 10.3 1.4 9.6 6.1 1.8 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase_Tyr PF07714.17 KIK45718.1 - 7.2e-28 97.6 0.0 9e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK45718.1 - 1.3e-24 87.0 0.0 1.4e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK45718.1 - 0.0018 17.6 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK45718.1 - 0.0086 16.0 0.1 0.011 15.7 0.1 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK45718.1 - 0.033 13.8 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family WD40 PF00400.32 KIK45719.1 - 2.7e-51 170.4 22.2 1.7e-07 31.8 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45719.1 - 4.2e-18 65.4 5.0 0.0018 18.5 0.1 6.0 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK45719.1 - 2.6e-13 49.6 2.7 0.039 12.9 0.0 6.7 1 1 6 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK45719.1 - 7.4e-06 25.8 0.2 5.4 7.1 0.0 5.1 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK45719.1 - 2.5e-05 23.1 3.7 0.0056 15.4 0.1 3.6 2 2 1 3 3 3 2 Nucleoporin Nup120/160 MMS1_N PF10433.9 KIK45719.1 - 0.017 13.8 0.0 0.56 8.8 0.0 2.6 2 1 1 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term IKI3 PF04762.12 KIK45719.1 - 0.042 11.9 0.4 0.069 11.1 0.2 1.3 1 1 0 1 1 1 0 IKI3 family WD40_like PF17005.5 KIK45719.1 - 0.072 12.4 0.0 16 4.7 0.0 3.0 2 1 0 3 3 3 0 WD40-like domain Proteasome_A_N PF10584.9 KIK45719.1 - 0.088 12.5 0.1 60 3.5 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Frtz PF11768.8 KIK45719.1 - 0.14 10.5 0.0 12 4.0 0.0 3.2 1 1 3 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz DEAD PF00270.29 KIK45720.1 - 1.6e-35 122.5 0.2 2.9e-35 121.6 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK45720.1 - 3.5e-19 69.2 0.2 1.2e-18 67.5 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 KIK45720.1 - 5.9e-05 23.4 0.1 0.00013 22.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIK45720.1 - 0.00026 20.8 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KIK45720.1 - 0.00028 20.5 0.0 0.00034 20.3 0.0 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 KIK45720.1 - 0.0005 20.1 0.0 0.0013 18.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIK45720.1 - 0.0025 18.1 1.5 0.013 15.8 0.7 2.4 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 KIK45720.1 - 0.026 15.0 0.0 0.078 13.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DNA_III_psi PF03603.13 KIK45720.1 - 0.05 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III psi subunit CMS1 PF14617.6 KIK45720.1 - 0.059 12.7 0.2 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.14 KIK45720.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Helicase Flavi_DEAD PF07652.14 KIK45720.1 - 0.15 12.0 0.3 0.51 10.3 0.3 2.0 1 1 0 1 1 1 0 Flavivirus DEAD domain Ribosomal_S11 PF00411.19 KIK45722.1 - 5.3e-47 158.8 1.6 6.6e-47 158.5 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 KIK45722.1 - 0.076 13.3 0.1 0.15 12.3 0.0 1.5 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) HTH_31 PF13560.6 KIK45724.1 - 0.0086 16.4 0.0 0.0086 16.4 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KIK45724.1 - 0.13 12.3 0.0 0.14 12.2 0.0 1.0 1 0 0 1 1 1 0 Helix-turn-helix domain FPP PF05911.11 KIK45727.1 - 0.00013 20.3 1.8 0.00017 20.0 1.8 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil zf-RING_2 PF13639.6 KIK45727.1 - 0.00042 20.6 16.4 0.00082 19.7 16.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KIK45727.1 - 0.00066 19.6 14.1 0.0012 18.7 14.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KIK45727.1 - 0.0026 17.6 16.0 0.005 16.7 16.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KIK45727.1 - 0.013 15.3 9.8 0.027 14.2 9.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 KIK45727.1 - 0.045 13.9 8.5 0.088 13.0 8.5 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KIK45727.1 - 0.064 13.1 15.4 0.13 12.2 15.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KIK45727.1 - 0.067 13.2 15.4 0.09 12.8 11.6 2.3 2 0 0 2 2 2 0 RING-type zinc-finger RNase_3_N PF18497.1 KIK45727.1 - 0.1 12.8 0.9 0.2 11.9 0.1 1.8 2 0 0 2 2 2 0 Ribonuclease III N-terminal domain zf-C3HC4_4 PF15227.6 KIK45727.1 - 0.53 10.5 13.4 2.6 8.3 14.0 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KIK45727.1 - 1.1 9.2 15.8 2.7 7.9 15.8 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Csm1_N PF18504.1 KIK45727.1 - 1.1 9.6 4.9 0.41 11.0 0.7 2.1 2 0 0 2 2 2 0 Csm1 N-terminal domain Baculo_IE-1 PF05290.11 KIK45727.1 - 1.3 9.0 10.5 0.27 11.2 5.5 2.1 2 1 1 3 3 3 0 Baculovirus immediate-early protein (IE-0) DUF4404 PF14357.6 KIK45727.1 - 2.2 9.0 7.0 13 6.5 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) HET PF06985.11 KIK45730.1 - 7.5e-12 45.8 3.9 1.7e-09 38.2 0.6 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_1 PF00515.28 KIK45730.1 - 0.00078 19.2 0.1 0.051 13.4 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK45730.1 - 0.0035 17.3 1.1 0.09 12.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK45730.1 - 0.14 12.4 0.3 0.3 11.3 0.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 WD40 PF00400.32 KIK45731.1 - 7.7e-50 165.8 23.9 2.9e-09 37.4 0.6 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45731.1 - 1.3e-24 86.3 3.6 0.00015 22.0 0.1 6.9 1 1 6 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK45731.1 - 1.1e-08 34.4 0.2 0.68 8.8 0.0 5.3 2 1 4 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK45731.1 - 1.7e-07 31.0 0.1 4.5 7.3 0.0 6.9 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK45731.1 - 0.0021 17.4 0.0 4.2 6.6 0.0 3.6 4 0 0 4 4 4 1 WD40-like domain Cytochrom_D1 PF02239.16 KIK45731.1 - 0.0099 14.5 2.3 7.9 4.9 0.1 3.1 2 1 1 3 3 3 3 Cytochrome D1 heme domain Frtz PF11768.8 KIK45731.1 - 0.016 13.5 0.0 3.8 5.7 0.0 3.0 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 KIK45731.1 - 0.017 13.8 4.9 0.093 11.4 0.2 3.0 2 1 2 4 4 4 0 Nucleoporin Nup120/160 IKI3 PF04762.12 KIK45731.1 - 0.034 12.1 4.5 1.4 6.8 2.0 2.7 1 1 2 3 3 3 0 IKI3 family NHL PF01436.21 KIK45731.1 - 0.11 12.6 0.1 82 3.5 0.0 4.0 3 0 0 3 3 3 0 NHL repeat zf-RING_2 PF13639.6 KIK45732.1 - 0.00042 20.6 15.8 0.00082 19.7 15.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KIK45732.1 - 0.00064 19.7 10.3 0.00064 19.7 10.3 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIK45732.1 - 0.0011 18.9 13.4 0.0019 18.1 13.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KIK45732.1 - 0.019 14.9 15.3 0.039 13.8 15.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK45732.1 - 0.025 14.7 14.9 0.049 13.8 14.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KIK45732.1 - 0.051 13.4 14.1 0.099 12.5 14.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 BRE1 PF08647.11 KIK45732.1 - 0.2 11.8 0.2 0.42 10.7 0.2 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase zf-RING_4 PF14570.6 KIK45732.1 - 0.66 9.8 10.9 1.4 8.8 10.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 KIK45732.1 - 0.94 9.4 15.4 2 8.3 15.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GLE1 PF07817.13 KIK45733.1 - 6e-47 160.0 0.0 1.4e-46 158.7 0.0 1.6 1 0 0 1 1 1 1 GLE1-like protein DUF4131 PF13567.6 KIK45733.1 - 0.41 10.3 2.5 0.45 10.2 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) TFIIA PF03153.13 KIK45733.1 - 1.2 9.1 19.4 1.6 8.7 19.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GST_N_3 PF13417.6 KIK45735.1 - 9.5e-14 51.6 0.0 1.7e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK45735.1 - 1.1e-08 35.3 0.0 2.3e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK45735.1 - 3.1e-08 33.9 0.1 7.2e-08 32.7 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK45735.1 - 1.6e-06 28.3 0.0 2.1e-05 24.6 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK45735.1 - 2.7e-05 24.3 0.0 6.9e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK45735.1 - 0.00013 21.9 0.0 0.00025 21.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KIK45735.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain WD40 PF00400.32 KIK45736.1 - 3.4e-54 179.6 24.5 2.1e-08 34.7 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45736.1 - 5.7e-25 87.4 7.0 6.4e-06 26.4 0.2 6.2 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK45736.1 - 3e-10 39.6 1.1 0.18 10.7 0.1 5.7 1 1 5 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK45736.1 - 1.2e-05 25.1 2.0 11 6.1 0.0 6.1 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Frtz PF11768.8 KIK45736.1 - 0.00016 20.1 0.1 0.51 8.6 0.0 3.8 2 1 2 4 4 4 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KIK45736.1 - 0.0038 16.6 0.0 10 5.3 0.0 4.1 3 1 1 4 4 4 2 WD40-like domain PQQ_3 PF13570.6 KIK45736.1 - 0.0099 16.3 0.1 17 6.0 0.0 4.4 4 0 0 4 4 4 1 PQQ-like domain CelD_N PF02927.14 KIK45736.1 - 0.056 14.3 0.0 2 9.3 0.0 2.7 2 1 0 2 2 2 0 Cellulase N-terminal ig-like domain Proteasome_A_N PF10584.9 KIK45736.1 - 0.096 12.4 0.8 37 4.1 0.0 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature F-box-like PF12937.7 KIK45737.1 - 0.00071 19.4 1.1 0.00071 19.4 1.1 2.6 2 1 0 2 2 2 1 F-box-like DUF1699 PF08004.11 KIK45737.1 - 0.072 12.8 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) zf-RING_5 PF14634.6 KIK45738.1 - 1.3e-07 31.5 9.1 1.9e-07 30.9 9.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIK45738.1 - 8.1e-07 28.8 10.4 1.8e-06 27.7 9.5 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KIK45738.1 - 1.9e-06 27.6 8.3 3.2e-06 26.9 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK45738.1 - 4.6e-06 26.6 7.7 1e-05 25.4 3.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIK45738.1 - 8.3e-06 26.0 11.5 1.6e-05 25.2 11.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIK45738.1 - 6.8e-05 22.7 7.7 0.00014 21.7 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK45738.1 - 0.0012 18.6 8.0 0.0035 17.1 8.0 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KIK45738.1 - 0.0047 16.3 6.6 0.043 13.2 6.6 2.1 1 1 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_4 PF15227.6 KIK45738.1 - 0.0075 16.4 12.0 0.071 13.3 12.1 2.5 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KIK45738.1 - 0.022 14.6 6.0 0.088 12.7 6.0 1.9 1 1 0 1 1 1 0 zf-RING of BARD1-type protein FYVE PF01363.21 KIK45738.1 - 0.022 14.9 6.1 0.042 14.0 1.8 2.2 1 1 1 2 2 2 0 FYVE zinc finger Rad50_zn_hook PF04423.14 KIK45738.1 - 0.041 13.7 1.4 0.19 11.6 1.4 2.2 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 KIK45738.1 - 0.08 12.7 7.2 0.2 11.5 7.2 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C2H2_jaz PF12171.8 KIK45738.1 - 0.082 13.2 0.0 0.082 13.2 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FUSC PF04632.12 KIK45738.1 - 0.83 8.1 5.2 2.7 6.4 5.6 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family zf-rbx1 PF12678.7 KIK45738.1 - 4.7 7.6 11.1 2.6 8.4 8.8 1.8 2 0 0 2 2 1 0 RING-H2 zinc finger domain FYDLN_acid PF09538.10 KIK45738.1 - 6.7 7.4 6.7 2e+02 2.7 6.7 2.4 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-RING_2 PF13639.6 KIK45739.1 - 8.8e-09 35.6 7.9 1.5e-08 34.8 7.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KIK45739.1 - 1.1e-08 34.9 8.0 2.1e-08 34.0 8.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIK45739.1 - 6.7e-08 32.4 3.5 1.5e-07 31.3 1.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KIK45739.1 - 3.8e-07 29.8 7.4 9.5e-07 28.6 7.4 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KIK45739.1 - 5.6e-07 29.3 8.7 1.1e-06 28.4 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK45739.1 - 1.7e-06 27.7 6.0 3.3e-06 26.9 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK45739.1 - 1e-05 25.3 7.6 2.3e-05 24.1 7.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK45739.1 - 5.2e-05 23.3 6.5 0.00023 21.3 6.6 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING FYVE PF01363.21 KIK45739.1 - 0.00019 21.5 5.9 0.0037 17.4 5.9 2.4 1 1 0 1 1 1 1 FYVE zinc finger DUF1272 PF06906.11 KIK45739.1 - 0.00072 19.6 3.4 0.00072 19.6 3.4 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 KIK45739.1 - 0.0039 17.0 4.8 0.0039 17.0 4.8 1.8 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KIK45739.1 - 0.0074 16.6 5.1 0.019 15.2 5.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KIK45739.1 - 0.0098 15.7 2.3 0.022 14.6 2.3 1.5 1 1 0 1 1 1 1 zf-RING of BARD1-type protein Rtf2 PF04641.12 KIK45739.1 - 0.014 14.8 5.6 0.066 12.6 5.6 2.1 1 1 0 1 1 1 0 Rtf2 RING-finger TruB_C_2 PF16198.5 KIK45739.1 - 0.022 14.9 0.2 0.16 12.1 0.0 2.5 3 0 0 3 3 3 0 tRNA pseudouridylate synthase B C-terminal domain FUSC PF04632.12 KIK45739.1 - 0.061 11.8 1.9 0.083 11.4 1.5 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family Baculo_IE-1 PF05290.11 KIK45739.1 - 0.095 12.6 2.5 0.12 12.4 1.1 1.8 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) DUF148 PF02520.17 KIK45739.1 - 0.12 12.5 2.6 0.2 11.8 2.2 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF148 zf-RING_10 PF16685.5 KIK45739.1 - 0.15 12.2 5.5 0.14 12.3 4.2 1.6 2 0 0 2 2 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 KIK45739.1 - 0.26 11.1 4.8 0.2 11.5 2.9 1.8 2 0 0 2 2 2 0 RING-like zinc finger zf-C2H2_4 PF13894.6 KIK45739.1 - 0.29 12.1 0.3 0.29 12.1 0.3 4.3 3 1 2 5 5 4 0 C2H2-type zinc finger DUF2321 PF10083.9 KIK45739.1 - 0.62 9.7 3.1 1.8 8.2 2.0 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-UDP PF14569.6 KIK45739.1 - 0.82 9.8 3.7 0.94 9.6 1.6 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger Synaptobrevin PF00957.21 KIK45741.1 - 4.1e-32 109.8 0.7 5.1e-32 109.5 0.7 1.1 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KIK45741.1 - 2.7e-08 33.7 0.0 4.6e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain ClpB_D2-small PF10431.9 KIK45741.1 - 0.096 12.8 0.2 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein Sec61_beta PF03911.16 KIK45742.1 - 1.3e-17 63.6 0.9 1.8e-17 63.1 0.4 1.5 2 0 0 2 2 2 1 Sec61beta family HET PF06985.11 KIK45744.1 - 1e-09 38.9 5.7 6.7e-07 29.8 1.2 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Profilin PF00235.19 KIK45745.1 - 1.6e-38 131.8 0.4 1.8e-38 131.7 0.4 1.0 1 0 0 1 1 1 1 Profilin LPD18 PF18832.1 KIK45745.1 - 0.0055 16.7 0.0 0.0089 16.1 0.0 1.5 1 0 0 1 1 1 1 Large polyvalent protein-associated domain 18 DUF2207 PF09972.9 KIK45746.1 - 0.26 10.0 1.6 0.35 9.6 1.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SecG PF03840.14 KIK45746.1 - 3.4 7.8 12.1 0.94 9.6 8.3 2.1 2 1 0 2 2 2 0 Preprotein translocase SecG subunit adh_short PF00106.25 KIK45749.1 - 4.6e-40 137.2 0.0 6e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK45749.1 - 1.6e-26 93.3 0.0 2e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KIK45749.1 - 3.2e-06 27.2 0.1 3.9e-06 26.9 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KIK45749.1 - 0.00018 21.5 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK45749.1 - 0.047 13.1 0.0 0.12 11.8 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RRM_1 PF00076.22 KIK45750.1 - 1.4e-35 120.9 0.0 8.6e-14 51.1 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KIK45750.1 - 0.0017 18.1 0.3 1 9.1 0.0 3.0 3 0 0 3 3 3 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 KIK45750.1 - 0.068 13.3 0.0 14 5.9 0.0 2.8 2 0 0 2 2 2 0 RNA recognition motif Forkhead PF00250.18 KIK45751.1 - 0.093 13.0 0.1 0.11 12.8 0.1 1.1 1 0 0 1 1 1 0 Forkhead domain DUF2934 PF11154.8 KIK45753.1 - 0.069 12.8 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) GPI-anchored PF10342.9 KIK45755.1 - 3.3e-08 34.2 0.4 7.2e-08 33.1 0.4 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF5608 PF18356.1 KIK45755.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5608) AsnC_trans_reg2 PF17805.1 KIK45756.1 - 0.044 13.9 0.1 0.047 13.9 0.1 1.3 1 0 0 1 1 1 0 AsnC-like ligand binding domain Aldolase_II PF00596.21 KIK45757.1 - 9.3e-45 152.8 0.0 1.1e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Prok-JAB PF14464.6 KIK45757.1 - 0.14 12.0 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain Oxidored_FMN PF00724.20 KIK45758.1 - 2.1e-84 283.7 0.0 2.6e-84 283.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family WD40 PF00400.32 KIK45760.1 - 1.1e-36 124.2 19.2 3.1e-08 34.2 1.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45760.1 - 4.3e-13 49.4 7.5 0.0061 16.8 0.2 6.3 2 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK45760.1 - 1.4e-05 23.9 2.4 0.67 8.5 0.1 3.4 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK45760.1 - 0.0026 16.8 0.1 0.44 9.4 0.0 3.6 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KIK45762.1 - 1.2e-36 124.1 27.6 8e-08 32.8 0.1 8.4 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45762.1 - 1.9e-11 44.1 8.2 0.053 13.8 0.3 6.8 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK45762.1 - 0.00024 20.2 0.2 0.22 10.5 0.0 3.6 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK45762.1 - 0.0074 15.0 10.7 0.52 8.9 0.2 4.0 3 1 2 5 5 5 3 Nucleoporin Nup120/160 WD40 PF00400.32 KIK45764.1 - 2.1e-11 44.1 1.4 4.6e-06 27.3 0.1 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.8 KIK45764.1 - 0.015 13.9 0.2 0.026 13.2 0.2 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 WD40 PF00400.32 KIK45765.1 - 3.2e-16 59.4 5.3 1.9e-05 25.3 0.0 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45765.1 - 6.9e-07 29.5 0.8 0.0076 16.5 0.1 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KIK45765.1 - 5.1e-05 22.8 0.1 0.00014 21.3 0.1 1.5 1 1 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK45765.1 - 0.023 14.0 0.0 1.2 8.4 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain Nup160 PF11715.8 KIK45765.1 - 0.043 12.4 0.0 0.25 10.0 0.0 1.8 1 1 0 2 2 2 0 Nucleoporin Nup120/160 GSH_synth_ATP PF03917.17 KIK45767.1 - 3.2e-121 404.6 0.0 4.1e-121 404.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KIK45767.1 - 1.6e-31 108.8 0.0 3.3e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DUF1771 PF08590.10 KIK45768.1 - 0.099 13.0 0.4 0.16 12.3 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) UbiA PF01040.18 KIK45770.1 - 4.8e-23 81.7 11.0 6.7e-23 81.3 11.0 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family p53-inducible11 PF14936.6 KIK45770.1 - 0.24 11.5 4.4 0.31 11.1 0.0 2.6 3 0 0 3 3 3 0 Tumour protein p53-inducible protein 11 Pkinase PF00069.25 KIK45771.1 - 1.7e-38 132.5 0.0 9.9e-38 130.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK45771.1 - 5.5e-15 55.3 0.0 1.6e-14 53.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK45771.1 - 0.0011 18.9 0.4 0.0068 16.3 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK45771.1 - 0.018 14.3 0.0 4.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 KIK45771.1 - 0.16 10.7 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase LSM PF01423.22 KIK45772.1 - 1e-18 66.8 0.9 1.3e-18 66.4 0.9 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIK45772.1 - 0.013 15.6 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain BPL_C PF02237.17 KIK45772.1 - 0.068 13.1 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain WD40 PF00400.32 KIK45774.1 - 9.5e-31 105.4 19.9 9.5e-07 29.4 1.8 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45774.1 - 2.4e-14 53.4 7.5 0.0012 19.1 0.2 6.1 2 1 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK45774.1 - 0.00019 20.3 7.2 0.65 8.6 0.6 3.9 3 1 0 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK45774.1 - 0.0015 17.5 0.0 0.28 10.1 0.0 3.7 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK45774.1 - 0.045 13.7 0.3 35 4.5 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Aldolase_II PF00596.21 KIK45775.1 - 1.2e-43 149.2 0.1 1.5e-43 148.9 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Aconitase PF00330.20 KIK45775.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) WD40 PF00400.32 KIK45777.1 - 4.3e-35 119.1 27.7 1.3e-07 32.1 4.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45777.1 - 7.5e-13 48.6 5.1 0.0046 17.2 0.1 6.1 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK45777.1 - 1.6e-05 24.9 0.6 0.0069 16.3 0.6 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK45777.1 - 0.00018 20.3 6.8 0.48 9.0 0.1 4.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK45777.1 - 0.0011 18.3 1.4 0.32 10.3 0.1 3.4 2 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK45777.1 - 0.0091 15.3 0.0 0.66 9.2 0.0 3.3 4 1 1 5 5 5 1 WD40-like domain PDDEXK_6 PF04720.12 KIK45777.1 - 0.037 14.0 0.0 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 PDDEXK-like family of unknown function Cytochrom_D1 PF02239.16 KIK45777.1 - 0.12 10.9 1.4 9.4 4.6 0.1 2.9 1 1 1 3 3 3 0 Cytochrome D1 heme domain PD40 PF07676.12 KIK45777.1 - 0.36 10.8 3.1 37 4.4 0.1 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat HET PF06985.11 KIK45779.1 - 6.2e-10 39.6 6.1 3.8e-08 33.8 1.5 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_1 PF00515.28 KIK45779.1 - 0.077 12.8 1.6 1.7 8.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK45779.1 - 0.078 13.1 1.5 24 5.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat FHA PF00498.26 KIK45780.1 - 1.3e-15 57.5 0.0 2.5e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIK45780.1 - 0.018 15.3 0.0 0.036 14.4 0.0 1.4 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain F-box-like PF12937.7 KIK45781.1 - 1e-08 34.9 0.5 1e-08 34.9 0.5 2.9 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIK45781.1 - 6.6e-08 32.2 0.3 5.6e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 F-box domain WD40 PF00400.32 KIK45781.1 - 2.1e-07 31.5 0.1 0.075 13.9 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45781.1 - 0.018 15.4 0.0 4.8 7.5 0.0 3.5 3 2 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain p450 PF00067.22 KIK45782.1 - 3.1e-62 210.9 0.0 3.5e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 KIK45783.1 - 2.8e-23 81.8 12.1 2.7e-09 37.5 0.9 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45783.1 - 6.4e-07 29.6 0.4 0.029 14.7 0.0 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK45783.1 - 0.0019 18.1 0.1 2 8.4 0.0 3.6 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK45783.1 - 0.019 13.9 0.1 0.39 9.6 0.0 2.3 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KIK45783.1 - 0.11 10.8 0.0 0.82 7.9 0.0 2.3 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 KIK45784.1 - 1.4e-32 111.2 8.6 2.1e-08 34.7 0.3 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45784.1 - 2.2e-13 50.3 0.5 6.4e-05 23.2 0.1 4.2 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK45784.1 - 4.6e-10 39.0 0.1 0.014 14.4 0.0 3.3 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK45784.1 - 0.0016 17.2 2.6 0.057 12.0 1.7 2.8 1 1 1 2 2 2 1 Nucleoporin Nup120/160 PD40 PF07676.12 KIK45784.1 - 0.024 14.6 0.1 9.1 6.4 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat HET PF06985.11 KIK45785.1 - 1.3e-13 51.5 2.5 1.1e-10 42.0 0.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) WD40 PF00400.32 KIK45787.1 - 2.6e-53 176.8 28.6 1.9e-09 38.0 0.8 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45787.1 - 7.8e-19 67.8 4.4 6.9e-05 23.1 0.0 6.3 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK45787.1 - 9.6e-11 41.2 0.2 0.17 10.8 0.0 5.6 2 1 4 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK45787.1 - 7.1e-06 25.8 0.1 4.7 7.3 0.0 5.8 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK45787.1 - 6.1e-05 21.9 6.2 0.077 11.6 0.2 4.4 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK45787.1 - 0.0014 18.0 4.2 0.52 9.6 0.1 4.3 2 1 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK45787.1 - 0.0014 18.0 0.0 0.022 14.1 0.0 2.3 2 1 0 2 2 2 1 WD40-like domain PALB2_WD40 PF16756.5 KIK45787.1 - 0.01 14.8 0.1 0.045 12.7 0.0 2.0 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain TPR_1 PF00515.28 KIK45787.1 - 0.021 14.6 0.1 17 5.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIK45787.1 - 0.075 13.7 0.2 0.19 12.4 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4082 PF13313.6 KIK45787.1 - 0.35 10.9 2.5 5.9 6.9 0.1 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4082) HET PF06985.11 KIK45788.1 - 1.3e-11 45.0 4.3 1.8e-09 38.1 0.6 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_16 PF13432.6 KIK45788.1 - 0.0033 18.1 0.4 0.0033 18.1 0.4 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK45788.1 - 0.25 11.6 1.9 36 4.8 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK45788.1 - 0.39 10.5 1.3 2.1 8.1 0.0 2.7 2 1 1 3 3 3 0 TPR repeat KR PF08659.10 KIK45789.1 - 5.2e-07 29.8 0.0 1.8e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 KR domain adh_short PF00106.25 KIK45789.1 - 8.5e-05 22.1 0.0 0.00082 18.9 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase DUF5368 PF17336.2 KIK45789.1 - 0.74 10.0 2.7 0.54 10.5 0.7 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5368) DUF2484 PF10658.9 KIK45789.1 - 8.9 6.7 6.8 7 7.0 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) SPT16 PF08644.11 KIK45790.1 - 7.7e-58 195.0 1.8 1.1e-57 194.4 0.2 2.2 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 KIK45790.1 - 4.9e-23 81.9 0.0 7.1e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KIK45790.1 - 6e-15 55.4 0.0 1.7e-14 54.0 0.0 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF3956 PF13104.6 KIK45790.1 - 0.19 12.0 0.1 0.42 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) Sec7 PF01369.20 KIK45792.1 - 1.4e-65 220.4 0.1 2.4e-65 219.6 0.1 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KIK45792.1 - 1.4e-20 73.8 0.1 1.6e-19 70.4 0.0 2.7 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KIK45792.1 - 0.067 13.0 1.7 0.94 9.4 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1981) Cytochrom_B561 PF03188.16 KIK45793.1 - 3.6e-10 40.1 7.9 5.7e-10 39.5 6.9 1.8 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF3522 PF12036.8 KIK45793.1 - 0.033 14.5 2.7 0.11 12.8 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3522) Sdh_cyt PF01127.22 KIK45793.1 - 0.037 14.1 1.6 0.037 14.1 1.6 2.5 2 1 1 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4149 PF13664.6 KIK45793.1 - 4.3 7.7 8.4 1.4 9.3 0.5 2.8 2 2 1 3 3 3 0 Domain of unknown function (DUF4149) NAD_binding_2 PF03446.15 KIK45795.1 - 9.1e-33 113.7 0.3 1.4e-32 113.1 0.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KIK45795.1 - 1.2e-28 99.7 0.0 3.6e-28 98.3 0.0 1.8 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KIK45795.1 - 0.036 14.6 0.0 0.12 13.0 0.0 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.25 KIK45796.1 - 1e-22 80.8 0.0 1.5e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK45796.1 - 5.5e-11 42.3 0.0 1.3e-10 41.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase DEAD PF00270.29 KIK45797.1 - 5.9e-24 84.8 0.1 1.1e-23 83.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KIK45797.1 - 4.6e-13 49.7 0.5 1.3e-12 48.3 0.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 KIK45797.1 - 2.1e-12 47.4 0.1 8.7e-10 38.9 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KIK45797.1 - 1.3e-08 35.0 0.2 2.3e-08 34.2 0.2 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 KIK45797.1 - 0.00078 19.8 0.0 0.002 18.5 0.0 1.7 1 0 0 1 1 1 1 DNA replication factor CDT1 like Abhydrolase_6 PF12697.7 KIK45800.1 - 4.8e-15 56.8 0.1 5.7e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK45800.1 - 7.7e-15 54.8 0.0 1.6e-14 53.7 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK45800.1 - 8.8e-15 55.0 0.1 1.1e-10 41.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 KIK45800.1 - 0.00012 21.7 0.0 0.042 13.4 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family FSH1 PF03959.13 KIK45800.1 - 0.0021 17.8 0.0 0.017 14.8 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Thioesterase PF00975.20 KIK45800.1 - 0.0023 18.1 0.0 0.0037 17.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 KIK45800.1 - 0.0039 17.1 0.0 0.067 13.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KIK45800.1 - 0.014 15.2 0.1 0.029 14.1 0.1 1.4 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_4 PF08386.10 KIK45800.1 - 0.029 14.5 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Ca_hom_mod PF14798.6 KIK45801.1 - 0.029 13.5 0.3 0.053 12.6 0.3 1.4 1 0 0 1 1 1 0 Calcium homeostasis modulator Proteasome PF00227.26 KIK45802.1 - 2.3e-59 200.1 0.0 3.3e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIK45802.1 - 2.6e-14 52.5 0.3 1.1e-13 50.6 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Luteo_P1-P2 PF08467.10 KIK45802.1 - 0.056 12.7 0.1 0.081 12.2 0.1 1.1 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase Peptidase_C78 PF07910.13 KIK45803.1 - 1.3e-43 148.9 0.0 7.7e-43 146.4 0.0 2.1 2 0 0 2 2 2 1 Peptidase family C78 Peptidase_C39_2 PF13529.6 KIK45803.1 - 0.11 13.1 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 Peptidase_C39 like family Toxin_12 PF07740.12 KIK45804.1 - 0.00085 20.0 7.1 0.0011 19.6 7.1 1.3 1 0 0 1 1 1 1 Ion channel inhibitory toxin HOOK PF05622.12 KIK45806.1 - 0.033 12.4 0.0 0.035 12.3 0.0 1.0 1 0 0 1 1 1 0 HOOK protein MAT1 PF06391.13 KIK45807.1 - 5.5e-55 186.4 15.4 6.9e-55 186.0 15.4 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KIK45807.1 - 1.6e-22 79.1 7.3 2.7e-22 78.4 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK45807.1 - 3.1e-06 26.9 5.1 5.8e-06 26.1 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK45807.1 - 1.5e-05 24.9 7.6 5.3e-05 23.1 7.9 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KIK45807.1 - 4.8e-05 23.6 7.2 8.1e-05 22.9 7.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK45807.1 - 6.2e-05 22.8 7.3 0.00013 21.7 7.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK45807.1 - 6.7e-05 22.7 5.5 0.00015 21.5 5.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK45807.1 - 0.0015 18.5 7.0 0.0054 16.7 2.4 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KIK45807.1 - 0.0045 16.8 9.7 0.078 12.9 10.0 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KIK45807.1 - 0.0098 15.7 3.9 0.067 13.0 1.4 2.2 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KIK45807.1 - 0.04 14.2 2.7 0.083 13.2 2.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain GAGA PF09237.11 KIK45807.1 - 0.11 12.4 2.4 0.14 12.0 0.1 2.3 2 0 0 2 2 2 0 GAGA factor ECH_2 PF16113.5 KIK45807.1 - 0.12 11.9 7.8 0.2 11.1 7.8 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DUF3519 PF12033.8 KIK45807.1 - 0.3 11.5 4.5 0.77 10.2 1.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3519) zf-C3HC4_4 PF15227.6 KIK45807.1 - 1.7 8.9 7.5 21 5.4 8.3 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-WRNIP1_ubi PF18279.1 KIK45807.1 - 6.2 7.7 5.6 37 5.3 0.4 2.5 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Pkinase PF00069.25 KIK45808.1 - 9.2e-67 225.2 0.0 1.1e-66 224.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK45808.1 - 1.8e-30 106.1 0.0 2.5e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK45808.1 - 0.0012 18.2 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KIK45808.1 - 0.23 10.5 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Adeno_E3_14_5 PF04834.12 KIK45808.1 - 2.2 8.9 5.0 5.6 7.6 5.0 1.6 1 0 0 1 1 1 0 Early E3 14.5 kDa protein Brix PF04427.18 KIK45809.1 - 5.6e-46 157.1 0.0 7.7e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF5308 PF17233.2 KIK45809.1 - 0.11 12.7 8.6 6.5 7.0 4.2 3.0 3 1 0 3 3 3 0 Family of unknown function (DUF5308) eIF-3c_N PF05470.12 KIK45809.1 - 0.34 9.1 13.3 0.47 8.7 13.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SDA1 PF05285.12 KIK45809.1 - 0.43 9.9 23.8 0.65 9.4 23.8 1.3 1 0 0 1 1 1 0 SDA1 PPL5 PF18168.1 KIK45809.1 - 0.52 9.6 4.7 0.8 8.9 4.7 1.3 1 0 0 1 1 1 0 Prim-pol family 5 CSRNP_N PF16019.5 KIK45809.1 - 1 9.2 5.9 1.8 8.4 5.9 1.4 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Paf1 PF03985.13 KIK45809.1 - 3.5 6.5 18.7 5.1 6.0 18.7 1.2 1 0 0 1 1 1 0 Paf1 Nop25 PF09805.9 KIK45809.1 - 4.1 7.9 24.2 8.5 6.8 24.2 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Nop14 PF04147.12 KIK45809.1 - 7.2 4.7 23.9 2.1 6.4 21.3 1.4 2 0 0 2 2 2 0 Nop14-like family Cyto_heme_lyase PF01265.17 KIK45811.1 - 2.7e-46 158.5 4.0 8.5e-45 153.6 4.0 2.2 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase NMO PF03060.15 KIK45812.1 - 5.1e-55 187.2 1.1 7.9e-55 186.5 1.1 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KIK45812.1 - 3.1e-11 42.9 0.1 1.4e-09 37.5 0.1 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KIK45812.1 - 5.8e-05 22.3 0.7 0.0001 21.4 0.7 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase GDP_Man_Dehyd PF16363.5 KIK45813.1 - 1.6e-156 520.8 0.0 1.8e-156 520.6 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIK45813.1 - 1.8e-69 233.9 0.0 2.3e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIK45813.1 - 0.0023 17.1 0.0 0.0036 16.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 KIK45813.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family DUF3445 PF11927.8 KIK45815.1 - 3.5e-73 245.9 0.0 4.4e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) WD40 PF00400.32 KIK45816.1 - 2.4e-17 63.0 12.1 6.9e-10 39.4 0.1 6.2 6 1 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KIK45816.1 - 0.0026 16.6 0.1 0.41 9.3 0.0 3.3 2 1 0 3 3 3 1 Nup133 N terminal like LVIVD PF08309.11 KIK45816.1 - 0.0047 16.2 0.1 0.062 12.6 0.0 2.3 2 0 0 2 2 2 1 LVIVD repeat ANAPC4_WD40 PF12894.7 KIK45816.1 - 0.07 13.4 0.0 22 5.5 0.0 3.4 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain TPR_14 PF13428.6 KIK45818.1 - 1.3e-11 44.3 11.8 13 6.9 0.0 11.3 10 2 2 12 12 10 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK45818.1 - 7.1e-06 25.7 11.6 0.39 10.9 0.1 7.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIK45818.1 - 0.00014 22.3 6.0 0.42 11.2 0.1 5.9 5 2 0 5 5 4 1 Tetratricopeptide repeat Suf PF05843.14 KIK45818.1 - 0.00029 20.9 10.9 0.016 15.2 3.8 4.9 3 1 1 4 4 4 1 Suppressor of forked protein (Suf) TPR_7 PF13176.6 KIK45818.1 - 0.00069 19.5 6.1 1.3 9.2 0.0 6.5 8 0 0 8 8 7 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KIK45818.1 - 0.0084 15.3 13.7 0.023 13.9 0.1 5.1 4 2 0 4 4 4 1 NRDE-2, necessary for RNA interference TPR_12 PF13424.6 KIK45818.1 - 0.018 15.3 9.5 11 6.4 0.1 5.6 6 1 0 6 6 6 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KIK45818.1 - 0.023 14.7 9.1 5.2 7.1 0.3 6.1 7 0 0 7 7 7 0 Mad3/BUB1 homology region 1 TPR_8 PF13181.6 KIK45818.1 - 0.025 14.7 9.2 27 5.3 0.2 7.0 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK45818.1 - 0.15 11.9 4.0 30 4.7 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat HAT PF02184.16 KIK45818.1 - 0.29 11.1 9.1 3.8 7.5 0.1 5.2 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat DALR_1 PF05746.15 KIK45818.1 - 0.52 10.5 2.5 7.5 6.8 0.0 3.2 3 0 0 3 3 3 0 DALR anticodon binding domain TPR_9 PF13371.6 KIK45818.1 - 4.6 7.5 6.4 8.8 6.6 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat PPTA PF01239.22 KIK45819.1 - 4.1e-42 140.7 25.6 2.2e-11 43.1 1.1 6.5 7 0 0 7 7 7 5 Protein prenyltransferase alpha subunit repeat Telomere_reg-2 PF10193.9 KIK45819.1 - 0.016 15.6 1.2 1.1 9.8 0.1 2.3 2 0 0 2 2 2 0 Telomere length regulation protein MTA_R1 PF17226.2 KIK45821.1 - 0.081 13.1 0.1 0.18 12.0 0.1 1.5 2 0 0 2 2 2 0 MTA R1 domain DUF4064 PF13273.6 KIK45821.1 - 0.23 11.7 7.2 3.8 7.8 7.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF2721 PF11026.8 KIK45821.1 - 1.8 8.5 15.2 1.2 9.0 1.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Sugar_tr PF00083.24 KIK45826.1 - 2.2e-75 254.2 18.4 2.8e-75 253.9 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK45826.1 - 4.6e-29 101.4 23.1 6.7e-29 100.9 23.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UPF0715 PF17094.5 KIK45826.1 - 0.0056 17.2 0.4 0.027 15.1 0.3 2.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0715) OATP PF03137.20 KIK45826.1 - 0.0057 15.0 1.9 0.033 12.5 0.6 2.3 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family ALIX_LYPXL_bnd PF13949.6 KIK45826.1 - 0.019 14.3 0.6 0.028 13.7 0.6 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF997 PF06196.12 KIK45826.1 - 5.7 7.0 8.0 3.6 7.7 4.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF997) VASP_tetra PF08776.11 KIK45827.1 - 0.026 14.1 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 VASP tetramerisation domain Polysacc_deac_1 PF01522.21 KIK45827.1 - 0.21 11.5 1.0 0.72 9.8 0.1 2.3 2 0 0 2 2 2 0 Polysaccharide deacetylase Got1 PF04178.12 KIK45828.1 - 5.5e-30 104.1 17.4 7.2e-30 103.7 17.4 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family HAGH_C PF16123.5 KIK45829.1 - 6.5e-22 77.8 0.0 1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KIK45829.1 - 2.4e-08 34.2 3.0 1.2e-07 31.9 3.0 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIK45829.1 - 0.032 13.7 0.2 0.48 9.9 0.2 2.1 1 1 0 1 1 1 0 Beta-lactamase superfamily domain TMEM154 PF15102.6 KIK45830.1 - 0.084 12.8 0.3 0.084 12.8 0.3 2.5 1 1 1 2 2 2 0 TMEM154 protein family Orthoreo_P10 PF07204.11 KIK45830.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Apt1 PF10351.9 KIK45830.1 - 1.1 8.1 4.7 1.4 7.7 4.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Tic110 PF16940.5 KIK45830.1 - 2.7 6.4 4.1 3.6 6.0 4.1 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Ndc1_Nup PF09531.10 KIK45830.1 - 5.1 5.7 9.9 7.3 5.1 9.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SPX PF03105.19 KIK45830.1 - 5.9 6.7 11.8 9.6 6.0 11.8 1.3 1 0 0 1 1 1 0 SPX domain SRP-alpha_N PF04086.13 KIK45832.1 - 7.9e-49 167.1 10.9 9.5e-47 160.3 10.9 2.2 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KIK45832.1 - 8.5e-46 156.1 0.3 7.6e-45 153.0 0.3 2.4 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KIK45832.1 - 1.7e-10 41.0 0.0 5e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KIK45832.1 - 2.5e-05 23.4 0.1 6.7e-05 22.0 0.1 1.6 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KIK45832.1 - 0.0024 17.6 0.0 0.0058 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KIK45832.1 - 0.0052 16.5 0.0 0.047 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KIK45832.1 - 0.0089 15.9 0.1 0.031 14.2 0.0 1.9 2 1 0 2 2 2 1 NTPase CbiA PF01656.23 KIK45832.1 - 0.015 15.3 0.0 0.044 13.8 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 KIK45832.1 - 0.036 13.5 0.0 0.074 12.5 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 KIK45832.1 - 0.039 13.1 0.9 2.6 7.1 0.9 2.3 1 1 0 1 1 1 0 Anion-transporting ATPase AAA_31 PF13614.6 KIK45832.1 - 0.051 13.5 0.1 1.5 8.7 0.0 2.3 1 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KIK45832.1 - 0.077 13.1 0.9 1.2 9.2 0.5 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase CsbD PF05532.12 KIK45832.1 - 0.18 11.8 3.7 2.7 8.0 0.2 2.7 2 0 0 2 2 2 0 CsbD-like DUF3618 PF12277.8 KIK45832.1 - 0.2 11.9 1.0 1.6 9.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) HemolysinCabind PF00353.19 KIK45833.1 - 0.0026 17.7 0.0 0.021 14.8 0.0 2.5 3 0 0 3 3 3 1 RTX calcium-binding nonapeptide repeat (4 copies) DUF4329 PF14220.6 KIK45833.1 - 0.039 14.0 0.2 61 3.6 0.0 4.1 4 1 1 5 5 5 0 Domain of unknown function (DUF4329) NACHT PF05729.12 KIK45834.1 - 0.00059 19.8 0.0 0.00078 19.4 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK45834.1 - 0.0011 19.3 0.0 0.0013 19.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KIK45834.1 - 0.015 15.7 0.0 0.021 15.2 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KIK45834.1 - 0.015 15.9 0.0 0.018 15.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KIK45834.1 - 0.04 13.8 0.1 0.061 13.2 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Na_Ala_symp PF01235.17 KIK45834.1 - 0.062 12.6 0.0 0.078 12.3 0.0 1.0 1 0 0 1 1 1 0 Sodium:alanine symporter family NB-ARC PF00931.22 KIK45834.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain TIP49 PF06068.13 KIK45834.1 - 0.17 11.0 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain Cyclin_N PF00134.23 KIK45837.1 - 1.2e-09 38.0 0.0 1.7e-08 34.3 0.0 2.3 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KIK45837.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 Cyclin C-terminal domain Img2 PF05046.14 KIK45840.1 - 1.3e-22 79.9 0.1 1.5e-22 79.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Syntaxin PF00804.25 KIK45840.1 - 0.033 13.8 0.0 0.036 13.8 0.0 1.0 1 0 0 1 1 1 0 Syntaxin SOR_SNZ PF01680.17 KIK45841.1 - 1.1e-111 371.5 4.5 1.8e-111 370.9 4.5 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KIK45841.1 - 3.4e-10 39.7 3.5 2e-07 30.6 0.1 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KIK45841.1 - 6.4e-05 22.2 0.3 0.13 11.3 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TetR_C_27 PF17935.1 KIK45841.1 - 0.00094 19.2 0.0 0.0024 17.9 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain NanE PF04131.14 KIK45841.1 - 0.0057 15.9 0.3 0.16 11.1 0.0 2.6 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.15 KIK45841.1 - 0.0064 15.9 1.8 0.26 10.6 0.1 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 KIK45841.1 - 0.0082 15.2 0.2 0.019 14.0 0.0 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase IGPS PF00218.21 KIK45841.1 - 0.029 13.6 0.0 0.31 10.2 0.0 2.5 2 1 1 3 3 3 0 Indole-3-glycerol phosphate synthase His_biosynth PF00977.21 KIK45841.1 - 0.06 12.8 0.2 0.96 8.9 0.0 2.5 2 1 0 2 2 2 0 Histidine biosynthesis protein Piwi PF02171.17 KIK45842.1 - 1e-69 235.1 0.0 1.8e-69 234.3 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 KIK45842.1 - 6.1e-18 64.2 0.1 1.6e-17 62.9 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 KIK45842.1 - 3.6e-14 53.6 0.0 6.9e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoMid PF16487.5 KIK45842.1 - 1.6e-08 34.7 0.0 5e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 KIK45842.1 - 6.6e-08 32.8 0.1 3.1e-06 27.4 0.0 2.8 2 0 0 2 2 2 1 Argonaute linker 2 domain PAZ PF02170.22 KIK45842.1 - 2.7e-06 27.2 0.0 5.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 PAZ domain Ras PF00071.22 KIK45843.1 - 2.7e-65 218.9 1.2 3.1e-65 218.7 1.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK45843.1 - 1.4e-36 125.4 0.1 2.2e-36 124.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK45843.1 - 2.9e-17 62.7 0.2 3.6e-17 62.4 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIK45843.1 - 4.2e-06 26.4 0.5 1.2e-05 25.0 0.5 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIK45843.1 - 4.9e-06 26.5 1.3 0.046 13.6 0.3 2.3 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KIK45843.1 - 1.1e-05 24.9 0.1 1.3e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KIK45843.1 - 1.2e-05 24.8 0.1 1.5e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KIK45843.1 - 3e-05 24.1 0.1 5.1e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KIK45843.1 - 0.0026 17.3 0.2 0.18 11.3 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 KIK45843.1 - 0.0033 17.8 0.0 0.52 10.7 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK45843.1 - 0.0068 16.8 0.0 0.0094 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 KIK45843.1 - 0.0096 15.5 0.1 0.044 13.3 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.6 KIK45843.1 - 0.045 14.0 0.0 0.087 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KIK45843.1 - 0.045 13.8 0.0 0.083 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KIK45843.1 - 0.048 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 KIK45843.1 - 0.072 12.4 0.0 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 Septin TniB PF05621.11 KIK45843.1 - 0.079 12.4 0.0 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 KIK45843.1 - 0.08 13.5 0.0 0.11 13.0 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Asp PF00026.23 KIK45844.1 - 8.9e-47 160.0 0.2 1.3e-46 159.5 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK45844.1 - 3e-05 24.3 4.7 0.011 16.0 0.7 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK45844.1 - 0.018 15.7 0.1 0.14 12.8 0.1 2.6 2 1 0 2 2 2 0 Aspartyl protease DUF2530 PF10745.9 KIK45844.1 - 0.56 10.5 3.0 1.2 9.4 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) zinc_ribbon_15 PF17032.5 KIK45845.1 - 1.4e-06 29.0 0.2 2e-06 28.4 0.2 1.3 1 0 0 1 1 1 1 zinc-ribbon family Zn_Tnp_IS1595 PF12760.7 KIK45845.1 - 0.046 13.7 1.7 0.12 12.3 1.7 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain FYVE_2 PF02318.16 KIK45845.1 - 0.1 12.8 2.5 7.3 6.8 0.2 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger EF-hand_1 PF00036.32 KIK45846.1 - 6.3e-22 75.4 1.3 9.5e-06 24.8 0.0 4.8 4 1 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KIK45846.1 - 4.1e-21 75.2 0.0 1.9e-09 37.8 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KIK45846.1 - 7.8e-20 69.1 2.6 3.2e-06 26.6 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KIK45846.1 - 2.6e-15 56.0 1.5 6.6e-09 35.5 0.1 4.2 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KIK45846.1 - 4.9e-15 54.3 0.4 0.0077 15.7 0.0 4.4 4 0 0 4 4 4 4 EF hand Caleosin PF05042.13 KIK45846.1 - 0.0081 16.1 0.0 0.054 13.4 0.0 2.4 1 1 2 3 3 3 1 Caleosin related protein EF-hand_9 PF14658.6 KIK45846.1 - 0.03 14.6 0.0 16 5.9 0.0 3.3 3 1 0 3 3 3 0 EF-hand domain GUN4 PF05419.12 KIK45846.1 - 0.054 13.6 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 GUN4-like EF-hand_10 PF14788.6 KIK45846.1 - 0.17 11.8 0.2 4.1 7.3 0.0 2.7 3 0 0 3 3 3 0 EF hand Zn_clus PF00172.18 KIK45847.1 - 1.6e-06 28.1 5.2 3.2e-06 27.1 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PET117 PF15786.5 KIK45847.1 - 0.24 11.7 0.6 0.52 10.6 0.6 1.5 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial Nop16 PF09420.10 KIK45848.1 - 6.4e-49 166.8 0.0 7.2e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 HAD_2 PF13419.6 KIK45849.1 - 0.00012 22.2 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK45849.1 - 0.12 12.6 0.0 13 6.0 0.0 2.2 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase QCR10 PF09796.9 KIK45850.1 - 4.5e-18 65.1 0.1 5.4e-18 64.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) 2OG-FeII_Oxy_2 PF13532.6 KIK45851.1 - 3.1e-26 92.8 0.1 4.5e-26 92.2 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_M24 PF00557.24 KIK45852.1 - 1.7e-40 139.0 0.0 2.3e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KIK45852.1 - 5.2e-08 33.6 0.0 1.2e-07 32.4 0.0 1.7 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain MFS_1 PF07690.16 KIK45854.1 - 9.4e-24 84.0 30.7 9.4e-24 84.0 30.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.28 KIK45855.1 - 5.2e-89 298.7 0.0 6.8e-89 298.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK45855.1 - 7.1e-05 23.7 0.4 0.00016 22.6 0.4 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_hydro_cc PF11790.8 KIK45856.1 - 1.6e-67 227.6 3.6 1.9e-67 227.3 3.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Apo-CIII PF05778.12 KIK45856.1 - 0.029 14.0 0.3 0.075 12.7 0.3 1.7 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) zf-Mss51 PF13824.6 KIK45857.1 - 2.4e-24 85.2 10.6 4.6e-24 84.3 10.6 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 DUF1610 PF07754.11 KIK45857.1 - 0.059 13.3 0.6 0.48 10.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) OrfB_Zn_ribbon PF07282.11 KIK45857.1 - 0.32 10.9 4.4 0.66 9.9 4.4 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Lar_restr_allev PF14354.6 KIK45857.1 - 3.7 8.0 7.3 7.1 7.1 7.3 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar IGPD PF00475.18 KIK45858.1 - 9.5e-60 201.1 0.2 1.6e-59 200.4 0.2 1.3 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase Peptidase_M13_N PF05649.13 KIK45859.1 - 7.4e-102 341.9 0.0 1e-101 341.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KIK45859.1 - 1.6e-61 207.5 0.0 3.4e-61 206.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M13 PH PF00169.29 KIK45861.1 - 6.4e-06 26.6 0.0 2.6e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 PH domain TMEM247 PF15444.6 KIK45861.1 - 5.7 6.9 8.1 4.1 7.4 0.1 3.3 3 0 0 3 3 3 0 Transmembrane protein 247 NYN PF01936.18 KIK45862.1 - 1.7e-25 90.3 0.0 3.1e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 NYN domain Methyltransf_11 PF08241.12 KIK45863.1 - 7.1e-09 36.2 0.0 1.7e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK45863.1 - 7.4e-07 29.8 0.0 9.4e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK45863.1 - 0.0017 18.2 0.0 0.0068 16.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KIK45863.1 - 0.15 11.8 0.0 0.4 10.4 0.0 1.7 2 0 0 2 2 2 0 Lysine methyltransferase RrnaAD PF00398.20 KIK45863.1 - 0.24 10.5 0.0 0.36 9.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NYN PF01936.18 KIK45866.1 - 4e-25 89.0 0.0 7.3e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 NYN domain THF_DHG_CYH PF00763.23 KIK45866.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Transcrip_reg PF01709.20 KIK45867.1 - 2.8e-56 190.6 0.3 3.2e-56 190.4 0.3 1.0 1 0 0 1 1 1 1 Transcriptional regulator Sulfate_transp PF00916.20 KIK45868.1 - 5.7e-115 384.1 17.4 7.6e-115 383.7 17.4 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KIK45868.1 - 7.1e-09 35.3 0.0 1.4e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KIK45868.1 - 0.023 15.0 1.1 0.039 14.3 0.0 1.9 3 0 0 3 3 3 0 STAS domain WD40 PF00400.32 KIK45869.1 - 1.2e-26 92.4 11.7 4.2e-09 36.9 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45869.1 - 4.3e-08 33.3 0.0 0.027 14.7 0.0 4.4 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK45869.1 - 0.0013 17.8 0.0 0.019 13.9 0.0 2.6 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein adh_short_C2 PF13561.6 KIK45871.1 - 5.2e-56 189.8 0.1 6.5e-56 189.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK45871.1 - 5.2e-41 140.3 0.4 6.9e-41 139.8 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK45871.1 - 1.7e-08 34.6 0.1 2.5e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK45871.1 - 0.042 13.3 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Replicase PF03090.17 KIK45872.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Replicase family adh_short_C2 PF13561.6 KIK45873.1 - 1.5e-52 178.5 0.0 1.9e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK45873.1 - 1.2e-35 122.7 0.0 1.5e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK45873.1 - 3.9e-07 30.2 0.0 5.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 KR domain PIN_4 PF13638.6 KIK45874.1 - 9.5e-20 71.2 0.2 9.5e-20 71.2 0.2 1.9 2 0 0 2 2 2 1 PIN domain EST1_DNA_bind PF10373.9 KIK45874.1 - 8.5e-11 41.8 0.0 2.6e-08 33.7 0.0 2.6 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain BUD22 PF09073.10 KIK45874.1 - 0.46 9.8 10.0 0.017 14.5 3.2 2.1 2 0 0 2 2 2 0 BUD22 NDK PF00334.19 KIK45875.1 - 1.4e-51 174.0 0.0 1.6e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase UCR_14kD PF02271.16 KIK45876.1 - 1.9e-38 130.5 0.3 2.2e-38 130.2 0.3 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF4541 PF15074.6 KIK45876.1 - 0.061 13.9 0.5 0.17 12.5 0.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4541) Transketolase_N PF00456.21 KIK45877.1 - 4.7e-151 502.5 0.0 6e-151 502.1 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KIK45877.1 - 6.4e-44 149.7 0.0 2.1e-43 148.1 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KIK45877.1 - 9.1e-14 51.4 0.0 1.7e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KIK45877.1 - 0.00011 21.5 0.1 0.00017 20.9 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Terpene_synth PF01397.21 KIK45877.1 - 0.093 12.4 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain Beta_elim_lyase PF01212.21 KIK45877.1 - 0.099 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DUF3343 PF11823.8 KIK45877.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) Cmc1 PF08583.10 KIK45878.1 - 5.6e-14 51.9 4.1 6.7e-14 51.7 4.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 KIK45878.1 - 0.003 17.3 0.7 0.0044 16.7 0.7 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.13 KIK45878.1 - 0.097 12.8 1.4 2.2 8.5 0.1 2.2 2 0 0 2 2 2 0 CHCH domain DUF3128 PF11326.8 KIK45878.1 - 4.3 7.8 7.6 12 6.3 7.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) OPT PF03169.15 KIK45879.1 - 2.6e-140 469.0 53.7 2.6e-140 469.0 53.7 1.5 1 1 1 2 2 2 1 OPT oligopeptide transporter protein RTC4 PF14474.6 KIK45880.1 - 1.4e-11 44.6 0.0 2.7e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain MFAP1 PF06991.11 KIK45882.1 - 0.058 13.2 0.3 0.075 12.9 0.3 1.1 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing RecO_C PF02565.15 KIK45883.1 - 0.039 13.7 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Recombination protein O C terminal DUF4218 PF13960.6 KIK45885.1 - 0.00026 20.6 0.0 0.00026 20.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Mago_nashi PF02792.14 KIK45886.1 - 0.15 12.2 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Mago nashi protein Pyridoxal_deC PF00282.19 KIK45887.1 - 3.7e-62 210.2 0.0 5.2e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KIK45887.1 - 1.4e-05 24.2 0.0 2.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V CUE PF02845.16 KIK45887.1 - 0.13 12.0 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 CUE domain DNA_pol_D_N PF18018.1 KIK45888.1 - 7e-43 145.8 0.0 1.1e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 KIK45888.1 - 1.5e-31 109.5 0.2 3.6e-30 104.9 0.2 2.1 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Hid1 PF12722.7 KIK45890.1 - 5.7e-179 597.0 0.0 7e-179 596.7 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KIK45890.1 - 1.3e-94 317.9 0.1 1.6e-94 317.5 0.1 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein T4_deiodinase PF00837.17 KIK45890.1 - 0.022 14.0 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 Iodothyronine deiodinase WD40 PF00400.32 KIK45891.1 - 3.7e-20 71.9 21.7 0.00016 22.4 1.6 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45891.1 - 1.7e-07 31.4 3.3 0.08 13.3 0.1 4.7 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK45891.1 - 3.7e-05 22.9 0.3 0.33 9.9 0.0 3.5 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Kelch_2 PF07646.15 KIK45891.1 - 2.2 8.4 5.8 8.2 6.6 0.0 3.8 5 0 0 5 5 5 0 Kelch motif Rad51 PF08423.11 KIK45892.1 - 4.1e-09 36.1 0.0 6.2e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Rad51 DnaB_C PF03796.15 KIK45892.1 - 0.019 14.3 0.1 0.027 13.8 0.1 1.1 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AEP1 PF17049.5 KIK45892.1 - 0.11 11.6 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 Atg8 PF02991.16 KIK45896.1 - 6.5e-52 174.1 0.2 7.7e-52 173.8 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KIK45896.1 - 6.9e-07 29.6 0.0 8.5e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 SH3_2 PF07653.17 KIK45896.1 - 0.061 13.0 0.0 0.11 12.1 0.0 1.4 1 1 0 1 1 1 0 Variant SH3 domain Band_7 PF01145.25 KIK45897.1 - 1.1e-05 25.5 0.0 1.1e-05 25.5 0.0 3.0 3 1 0 3 3 3 1 SPFH domain / Band 7 family Glyco_hydro_63 PF03200.16 KIK45898.1 - 7.4e-159 529.6 0.0 8e-157 522.9 0.0 2.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KIK45898.1 - 5.3e-75 252.4 0.0 2.7e-74 250.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KIK45898.1 - 0.00013 20.9 0.0 0.00032 19.7 0.0 1.5 2 0 0 2 2 2 1 Trehalase AGP PF06376.12 KIK45898.1 - 0.016 15.0 0.3 0.045 13.6 0.3 1.8 1 0 0 1 1 1 0 Arabinogalactan peptide Pyr_redox_2 PF07992.14 KIK45899.1 - 5.5e-66 222.8 9.1 8.8e-66 222.1 9.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KIK45899.1 - 1.9e-42 144.0 0.3 1.9e-42 144.0 0.3 2.7 2 1 2 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KIK45899.1 - 5.4e-22 78.1 7.4 4.4e-19 68.8 2.2 3.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIK45899.1 - 2.3e-10 40.4 0.4 2.3e-10 40.4 0.4 3.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KIK45899.1 - 3.2e-10 39.7 2.1 3.2e-10 39.7 2.1 2.7 2 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KIK45899.1 - 3.2e-10 39.8 11.3 1.4e-07 31.1 1.6 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK45899.1 - 2.6e-09 37.2 2.8 2.8e-05 24.3 0.2 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIK45899.1 - 1.2e-06 27.9 2.0 1.2e-06 27.9 2.0 3.3 3 0 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 KIK45899.1 - 2.2e-06 27.0 2.9 0.0056 15.9 0.1 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KIK45899.1 - 2.6e-06 26.4 16.0 0.00045 19.0 1.1 4.1 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.17 KIK45899.1 - 0.00021 20.6 6.2 0.0012 18.2 0.2 2.6 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 KIK45899.1 - 0.00029 20.2 9.3 0.028 13.7 2.6 3.5 3 1 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KIK45899.1 - 0.0024 17.2 12.2 0.037 13.3 0.7 3.4 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.24 KIK45899.1 - 0.013 15.1 19.2 0.6 9.6 0.2 4.2 3 1 1 4 4 4 0 FAD dependent oxidoreductase THF_DHG_CYH_C PF02882.19 KIK45899.1 - 0.017 14.4 0.2 0.017 14.4 0.2 2.6 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Amino_oxidase PF01593.24 KIK45899.1 - 0.1 11.8 0.1 0.8 8.9 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 KIK45899.1 - 0.45 11.0 2.0 1.9 8.9 0.2 2.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Lactamase_B_2 PF12706.7 KIK45901.1 - 5.1e-07 29.4 0.1 0.00093 18.8 0.2 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIK45901.1 - 0.00072 19.6 0.2 0.0019 18.3 0.2 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Pkinase PF00069.25 KIK45904.1 - 1e-63 215.2 0.0 1.2e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK45904.1 - 1.5e-25 90.0 0.0 2e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK45904.1 - 0.00019 20.9 0.0 0.00054 19.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KIK45904.1 - 0.00072 19.5 0.2 0.034 14.1 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIK45904.1 - 0.026 14.1 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KIK45904.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 KIK45905.1 - 1.2e-46 155.7 22.1 6.1e-08 33.2 0.1 9.0 8 1 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 KIK45905.1 - 3.8e-12 45.9 0.5 7.9e-12 44.9 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK45905.1 - 6.9e-11 41.8 1.1 1.2e-10 40.9 0.2 2.1 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.8 KIK45905.1 - 2.9e-10 39.4 9.1 0.3 9.7 0.0 6.1 4 1 2 6 6 6 5 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KIK45905.1 - 9.7e-06 25.8 1.4 0.76 10.1 0.1 5.0 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KIK45905.1 - 2e-05 24.5 0.1 0.00075 19.4 0.0 3.2 3 0 0 3 3 3 1 F-box BBS2_Mid PF14783.6 KIK45905.1 - 5.6e-05 23.1 0.3 15 5.6 0.0 5.2 3 2 3 6 6 6 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 KIK45905.1 - 0.052 12.3 0.3 11 4.6 0.0 4.1 3 1 1 5 5 5 0 Nup133 N terminal like LigB PF02900.18 KIK45906.1 - 2.4e-34 118.6 0.0 3e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase UPF0262 PF06793.12 KIK45906.1 - 0.17 12.0 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) COQ7 PF03232.13 KIK45908.1 - 2.1e-69 232.7 0.0 2.5e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 NDUF_B4 PF07225.12 KIK45909.1 - 2.7e-05 24.0 0.1 3e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) G-patch PF01585.23 KIK45910.1 - 2.1e-13 49.9 1.9 4.6e-13 48.8 1.9 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KIK45910.1 - 4.3e-08 32.9 1.1 0.0067 16.2 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 KIK45910.1 - 2.5e-05 24.2 1.2 2.5e-05 24.2 1.2 2.3 2 0 0 2 2 2 1 G-patch domain RED_N PF07808.13 KIK45910.1 - 0.0058 16.3 0.7 0.0058 16.3 0.7 1.7 2 0 0 2 2 2 1 RED-like protein N-terminal region zf-C2H2_jaz PF12171.8 KIK45910.1 - 0.012 15.9 1.4 0.03 14.6 1.4 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding PBP PF01161.20 KIK45911.1 - 1.8e-14 54.2 0.2 2.6e-14 53.7 0.2 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein FH2 PF02181.23 KIK45912.1 - 6.6e-78 262.4 5.9 6.6e-78 262.4 5.9 1.9 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 KIK45912.1 - 7.4e-30 104.0 0.2 7.4e-30 104.0 0.2 2.7 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 KIK45912.1 - 3.4e-27 95.2 2.6 3.9e-27 95.1 0.0 2.4 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Mce4_CUP1 PF11887.8 KIK45912.1 - 0.0099 15.4 0.5 0.46 9.9 0.3 2.5 2 0 0 2 2 2 1 Cholesterol uptake porter CUP1 of Mce4, putative Syntaxin_2 PF14523.6 KIK45912.1 - 0.01 16.2 5.7 0.051 14.0 0.0 3.7 3 0 0 3 3 3 0 Syntaxin-like protein Dak2 PF02734.17 KIK45912.1 - 0.23 11.4 1.6 0.76 9.6 1.1 2.3 2 0 0 2 2 2 0 DAK2 domain DinB_2 PF12867.7 KIK45912.1 - 2.2 8.8 8.1 1.3 9.5 0.4 3.6 4 0 0 4 4 4 0 DinB superfamily CAMP_factor PF07373.11 KIK45912.1 - 3.4 7.2 7.0 8 6.0 0.1 3.2 3 0 0 3 3 3 0 CAMP factor (Cfa) V_ATPase_I PF01496.19 KIK45912.1 - 7 4.4 12.2 0.2 9.6 1.0 2.7 2 1 1 3 3 3 0 V-type ATPase 116kDa subunit family Glycophorin_A PF01102.18 KIK45913.1 - 0.021 15.1 0.2 0.033 14.4 0.2 1.5 1 0 0 1 1 1 0 Glycophorin A DUF3341 PF11821.8 KIK45913.1 - 0.11 12.1 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) EphA2_TM PF14575.6 KIK45913.1 - 0.16 12.9 0.1 0.18 12.7 0.1 1.3 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Myosin_head PF00063.21 KIK45914.1 - 2.8e-256 852.1 0.0 5.1e-256 851.2 0.0 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 KIK45914.1 - 3.2e-26 91.6 1.5 3.2e-26 91.6 1.5 3.5 3 0 0 3 3 3 1 DIL domain IQ PF00612.27 KIK45914.1 - 4.1e-11 41.7 41.2 0.00047 19.7 1.5 7.0 6 0 0 6 6 6 4 IQ calmodulin-binding motif AAA_22 PF13401.6 KIK45914.1 - 0.016 15.5 0.0 0.069 13.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain Myosin_N PF02736.19 KIK45914.1 - 0.1 12.4 0.4 0.26 11.1 0.4 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 KIK45914.1 - 0.22 11.9 0.0 0.22 11.9 0.0 3.4 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KIK45914.1 - 0.58 10.7 2.7 3.6 8.1 0.0 2.8 3 0 0 3 3 3 0 ABC transporter HMMR_C PF15908.5 KIK45914.1 - 0.74 10.1 13.6 26 5.1 13.0 3.2 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal DUF4795 PF16043.5 KIK45914.1 - 4.3 6.9 16.2 0.49 10.0 9.9 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) zf-AN1 PF01428.16 KIK45915.1 - 5.5e-15 55.2 19.1 1.5e-07 31.4 9.4 2.5 2 0 0 2 2 2 2 AN1-like Zinc finger C1_4 PF07975.12 KIK45915.1 - 0.0085 16.3 2.6 0.0085 16.3 2.6 2.4 2 0 0 2 2 2 1 TFIIH C1-like domain IFNGR1 PF07140.11 KIK45915.1 - 0.13 12.3 2.2 0.29 11.2 2.2 1.6 1 0 0 1 1 1 0 Interferon gamma receptor (IFNGR1) IBR PF01485.21 KIK45915.1 - 0.73 10.1 14.0 0.24 11.7 4.6 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Snf7 PF03357.21 KIK45916.1 - 5.6e-41 140.0 19.9 5.6e-41 140.0 19.9 1.6 2 0 0 2 2 2 1 Snf7 HTH_6 PF01418.17 KIK45916.1 - 0.089 12.8 0.9 0.26 11.3 0.5 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain, rpiR family Pathogen_betaC1 PF09593.10 KIK45916.1 - 0.28 11.1 2.3 0.5 10.3 2.3 1.3 1 0 0 1 1 1 0 Beta-satellite pathogenicity beta C1 protein Resolvase PF00239.21 KIK45916.1 - 0.33 11.1 8.1 1 9.4 7.1 2.3 1 1 0 1 1 1 0 Resolvase, N terminal domain DUF1002 PF06207.11 KIK45916.1 - 0.44 10.0 6.1 0.092 12.3 1.3 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1002) DUF4407 PF14362.6 KIK45916.1 - 0.61 9.4 6.4 0.83 9.0 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) KfrA_N PF11740.8 KIK45916.1 - 1.2 9.9 7.2 1.6 9.4 0.8 2.8 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term YlqD PF11068.8 KIK45916.1 - 1.3 9.4 14.4 1.5 9.2 6.2 2.2 1 1 1 2 2 2 0 YlqD protein Exonuc_VII_L PF02601.15 KIK45916.1 - 6.1 6.3 11.1 7.3 6.1 10.5 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit COG2 PF06148.11 KIK45916.1 - 6.8 6.8 13.0 1.6 8.8 5.0 3.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 COG4 PF08318.12 KIK45917.1 - 6.9e-96 321.2 0.1 1e-95 320.7 0.1 1.2 1 0 0 1 1 1 1 COG4 transport protein Laminin_I PF06008.14 KIK45917.1 - 0.0032 17.2 1.8 0.0091 15.7 1.0 2.0 2 0 0 2 2 2 1 Laminin Domain I RINT1_TIP1 PF04437.13 KIK45917.1 - 0.0052 15.7 0.0 0.014 14.4 0.0 1.7 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Dor1 PF04124.12 KIK45917.1 - 0.016 13.9 0.2 0.037 12.7 0.2 1.6 1 0 0 1 1 1 0 Dor1-like family UPF0158 PF03682.13 KIK45917.1 - 0.058 13.4 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) Spc7 PF08317.11 KIK45917.1 - 0.32 9.9 8.7 2.3 7.0 2.6 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein HSCB_C PF07743.13 KIK45917.1 - 0.65 10.5 2.7 2.4 8.7 0.1 3.1 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain DUF2340 PF10209.9 KIK45918.1 - 2.9e-50 169.7 0.2 3.4e-50 169.5 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Ubiquitin_4 PF18036.1 KIK45918.1 - 0.07 13.2 0.0 0.55 10.3 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-like domain DnaJ_C PF01556.18 KIK45919.1 - 7.5e-39 133.2 0.3 1e-38 132.8 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIK45919.1 - 1.3e-19 70.0 0.5 2.3e-19 69.3 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KIK45919.1 - 1.2e-15 57.6 18.0 2.3e-15 56.7 18.0 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KIK45919.1 - 0.018 15.0 16.6 0.019 14.9 3.6 2.4 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein RseC_MucC PF04246.12 KIK45919.1 - 1.1 9.2 5.3 1.4 8.9 0.9 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Cytochrome_C7 PF14522.6 KIK45919.1 - 2.6 8.1 7.3 27 4.8 7.3 2.4 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c HypA PF01155.19 KIK45919.1 - 4.1 7.4 10.4 4.4 7.3 3.4 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CN_hydrolase PF00795.22 KIK45920.1 - 7.8e-55 186.0 0.0 8.7e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DAGK_cat PF00781.24 KIK45921.1 - 3.4e-14 52.5 0.0 5.8e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain WD40 PF00400.32 KIK45922.1 - 0.012 16.5 10.9 0.084 13.8 0.1 4.5 4 1 0 4 4 4 0 WD domain, G-beta repeat Fungal_trans PF04082.18 KIK45923.1 - 5.9e-08 32.1 0.3 1.2e-07 31.0 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK45923.1 - 5.1e-05 23.3 10.2 0.0001 22.3 10.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_9_N PF15420.6 KIK45924.1 - 0.014 15.4 0.1 0.026 14.5 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF1690 PF07956.11 KIK45925.1 - 7.2e-23 81.6 2.4 9.8e-23 81.1 2.4 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) LUC7 PF03194.15 KIK45925.1 - 0.096 12.3 2.3 0.12 12.0 2.3 1.1 1 0 0 1 1 1 0 LUC7 N_terminus HA2 PF04408.23 KIK45926.1 - 1e-15 57.9 0.0 2.2e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KIK45926.1 - 2.9e-13 50.1 0.1 8.3e-13 48.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KIK45926.1 - 1.1e-11 45.0 0.0 2.2e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KIK45926.1 - 2.5e-07 30.7 0.0 6.2e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KIK45926.1 - 8.7e-05 22.8 0.0 0.00023 21.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIK45926.1 - 0.0017 18.1 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KIK45926.1 - 0.009 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 KIK45926.1 - 0.026 14.9 0.0 0.092 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KIK45926.1 - 0.058 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KIK45926.1 - 0.16 12.4 0.1 0.34 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain Mis14 PF08641.12 KIK45927.1 - 0.0025 18.2 0.4 0.0041 17.4 0.1 1.6 2 0 0 2 2 2 1 Kinetochore protein Mis14 like Gar1 PF04410.14 KIK45928.1 - 9.3e-39 132.7 0.0 1.1e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region AAA PF00004.29 KIK45929.1 - 7.8e-60 201.1 0.0 9.6e-45 152.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK45929.1 - 1.7e-08 35.0 1.8 0.011 16.2 0.0 4.2 3 2 1 4 4 4 2 AAA ATPase domain AAA_18 PF13238.6 KIK45929.1 - 8.5e-06 26.3 0.0 0.031 14.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 KIK45929.1 - 1.2e-05 25.0 3.2 1.2e-05 25.0 0.0 2.6 3 0 0 3 3 3 1 AAA+ lid domain AAA_5 PF07728.14 KIK45929.1 - 2.8e-05 24.1 0.1 0.033 14.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KIK45929.1 - 3.1e-05 23.8 0.0 0.0023 17.7 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KIK45929.1 - 6.4e-05 22.9 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 KIK45929.1 - 8e-05 22.0 0.0 0.028 13.6 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_25 PF13481.6 KIK45929.1 - 0.0001 22.0 0.2 0.0025 17.4 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_28 PF13521.6 KIK45929.1 - 0.0001 22.6 0.0 0.46 10.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KIK45929.1 - 0.00016 22.0 0.2 0.021 15.1 0.1 3.2 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.6 KIK45929.1 - 0.00019 21.4 0.0 0.42 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KIK45929.1 - 0.0006 20.2 0.0 0.093 13.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase ATPase PF06745.13 KIK45929.1 - 0.0019 17.6 0.4 0.012 14.9 0.0 2.3 3 0 0 3 3 2 1 KaiC AAA_33 PF13671.6 KIK45929.1 - 0.0023 18.1 0.0 0.39 10.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KIK45929.1 - 0.003 17.3 0.0 0.01 15.6 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KIK45929.1 - 0.0051 16.2 1.0 0.045 13.1 0.1 2.6 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 KIK45929.1 - 0.0064 16.6 0.0 0.017 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 KIK45929.1 - 0.011 15.4 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KIK45929.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 KIK45929.1 - 0.016 15.6 0.0 8.2 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KIK45929.1 - 0.024 14.4 0.1 0.2 11.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KIK45929.1 - 0.026 14.0 0.0 0.15 11.6 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 KIK45929.1 - 0.03 13.8 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Vps4_C PF09336.10 KIK45929.1 - 0.04 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain DUF815 PF05673.13 KIK45929.1 - 0.041 13.0 0.0 0.36 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.12 KIK45929.1 - 0.065 13.2 0.2 3.4 7.5 0.1 2.7 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 KIK45929.1 - 0.077 12.9 0.0 4.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain T2SSE PF00437.20 KIK45929.1 - 0.081 12.0 0.0 4 6.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_3 PF07726.11 KIK45929.1 - 0.1 12.5 0.0 0.66 9.8 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KIK45929.1 - 0.1 11.7 0.0 5.6 6.1 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain IPT PF01745.16 KIK45929.1 - 0.11 11.8 0.1 5.1 6.4 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase eIF_4G1 PF12152.8 KIK45930.1 - 5.8 7.2 7.0 12 6.2 1.1 3.1 1 1 2 3 3 3 0 Eukaryotic translation initiation factor 4G1 DUF402 PF04167.13 KIK45934.1 - 0.0033 17.6 0.0 0.0055 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF402) Complex1_LYR PF05347.15 KIK45935.1 - 2.7e-09 36.9 0.4 4.1e-09 36.3 0.4 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) RRN3 PF05327.11 KIK45936.1 - 2.1e-185 617.5 0.0 3.2e-185 616.9 0.0 1.2 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 GCIP PF13324.6 KIK45936.1 - 0.061 12.9 0.8 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting IIGP PF05049.13 KIK45939.1 - 5.4e-22 78.4 0.0 1.3e-21 77.1 0.0 1.6 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KIK45939.1 - 0.00018 21.5 0.0 0.00068 19.7 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KIK45939.1 - 0.0078 16.0 0.2 3.3 7.4 0.1 2.4 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KIK45939.1 - 0.0095 15.9 0.0 0.044 13.7 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KIK45939.1 - 0.015 15.7 0.0 0.015 15.7 0.0 4.0 3 1 0 3 3 2 0 AAA ATPase domain AAA_29 PF13555.6 KIK45939.1 - 0.047 13.4 0.1 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Roc PF08477.13 KIK45939.1 - 0.068 13.4 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Viral_helicase1 PF01443.18 KIK45939.1 - 0.073 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Dynamin_N PF00350.23 KIK45939.1 - 0.39 10.7 0.0 0.39 10.7 0.0 3.3 2 1 0 2 2 1 0 Dynamin family ABC_tran PF00005.27 KIK45939.1 - 0.46 11.0 0.0 0.46 11.0 0.0 3.7 3 1 0 3 3 2 0 ABC transporter MeaB PF03308.16 KIK45939.1 - 0.76 8.7 0.0 0.76 8.7 0.0 2.6 2 1 1 3 3 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KIK45939.1 - 0.77 10.0 0.0 0.77 10.0 0.0 3.0 2 1 0 2 2 1 0 AAA domain AAA_18 PF13238.6 KIK45939.1 - 1.5 9.4 0.0 1.5 9.4 0.0 3.4 2 1 0 2 2 1 0 AAA domain LPP20 PF02169.16 KIK45943.1 - 3.3 8.1 11.4 11 6.5 11.3 1.9 1 1 0 1 1 1 0 LPP20 lipoprotein F-box-like PF12937.7 KIK45944.1 - 0.00064 19.6 1.3 0.0015 18.4 0.2 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK45944.1 - 0.0013 18.5 0.0 0.0047 16.8 0.0 2.0 1 0 0 1 1 1 1 F-box domain GST_C_6 PF17171.4 KIK45944.1 - 0.029 14.1 0.0 0.084 12.7 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain F-box_4 PF15966.5 KIK45944.1 - 0.067 13.1 0.2 0.4 10.6 0.0 2.4 3 0 0 3 3 3 0 F-box DUF2070 PF09843.9 KIK45945.1 - 2.3 6.4 4.6 4.3 5.5 4.6 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CHAT PF12770.7 KIK45948.1 - 1.2e-31 110.3 0.1 2.2e-31 109.4 0.1 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK45948.1 - 2.6e-06 27.1 9.0 0.31 11.0 0.1 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK45948.1 - 0.0016 18.3 0.0 19 5.6 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIK45948.1 - 0.0093 16.2 14.2 10 6.5 0.5 7.7 7 2 1 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK45948.1 - 0.011 16.4 10.4 62 4.8 0.0 8.0 9 0 0 9 9 9 0 Tetratricopeptide repeat SMBP PF16785.5 KIK45948.1 - 0.016 15.5 0.5 0.056 13.7 0.0 2.3 2 0 0 2 2 2 0 Small metal-binding protein TPR_1 PF00515.28 KIK45948.1 - 0.19 11.6 7.5 59 3.7 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat HET PF06985.11 KIK45950.1 - 3e-08 34.1 6.3 8.8e-07 29.4 1.0 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) WD40 PF00400.32 KIK45955.1 - 4.3e-12 46.3 6.0 0.082 13.8 0.0 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK45955.1 - 2.2e-06 27.9 0.0 0.13 12.6 0.0 3.8 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK45955.1 - 0.0002 21.2 0.1 0.56 10.2 0.0 3.6 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KIK45955.1 - 0.00049 20.0 0.0 0.2 11.5 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KIK45955.1 - 0.0027 16.3 0.0 0.0073 14.9 0.0 1.7 2 1 0 2 2 2 1 Cytochrome D1 heme domain IU_nuc_hydro PF01156.19 KIK45956.1 - 4.1e-86 289.3 0.1 4.8e-86 289.1 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase HET PF06985.11 KIK45958.1 - 2.4e-09 37.7 15.9 1e-07 32.4 3.4 3.5 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) ERp29_N PF07912.13 KIK45958.1 - 0.075 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 ERp29, N-terminal domain Peptidase_S49_N PF08496.10 KIK45958.1 - 2.6 8.1 9.8 6.5 6.8 9.8 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RNA_polI_A34 PF08208.11 KIK45958.1 - 2.9 7.9 20.9 0.023 14.8 11.5 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 RNA_pol_Rpc4 PF05132.14 KIK45958.1 - 5.6 7.4 15.2 0.16 12.4 3.7 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 FH2 PF02181.23 KIK45961.1 - 4.5e-80 269.6 3.7 3.5e-79 266.6 0.0 2.4 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KIK45961.1 - 1.5e-26 93.1 0.0 1.7e-21 76.7 0.0 2.6 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KIK45961.1 - 8.9e-19 67.9 0.2 8.9e-19 67.9 0.2 2.7 3 0 0 3 3 3 1 Diaphanous FH3 Domain TMPIT PF07851.13 KIK45961.1 - 0.57 9.4 5.8 1.2 8.3 5.8 1.5 1 0 0 1 1 1 0 TMPIT-like protein Seryl_tRNA_N PF02403.22 KIK45961.1 - 0.95 9.7 18.6 0.25 11.6 8.3 4.0 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TPD52 PF04201.15 KIK45961.1 - 2 8.0 16.0 3.4 7.3 1.1 4.0 2 1 1 3 3 3 0 Tumour protein D52 family FAM76 PF16046.5 KIK45961.1 - 6.9 5.9 16.3 31 3.8 16.2 2.0 1 1 0 1 1 1 0 FAM76 protein DUF5570 PF17731.1 KIK45962.1 - 0.013 15.6 0.1 0.015 15.4 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5570) MCM PF00493.23 KIK45963.1 - 1.2e-103 345.1 0.6 1.2e-103 345.1 0.6 1.6 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KIK45963.1 - 1.4e-38 131.6 0.0 2.5e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KIK45963.1 - 4.2e-29 101.0 0.6 1.1e-28 99.6 0.6 1.8 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 KIK45963.1 - 1.9e-26 92.7 1.2 5.7e-26 91.1 1.2 1.9 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 KIK45963.1 - 7.6e-25 87.2 1.7 1.6e-24 86.1 1.2 1.9 2 0 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KIK45963.1 - 7.4e-08 32.0 0.0 1.8e-06 27.5 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KIK45963.1 - 0.0017 18.2 0.0 0.0041 17.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KIK45963.1 - 0.0034 17.1 0.0 0.007 16.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KIK45963.1 - 0.029 14.4 0.0 0.082 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Y_phosphatase3 PF13350.6 KIK45964.1 - 8.9e-57 192.7 0.0 3.4e-55 187.6 0.0 2.0 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KIK45964.1 - 0.00052 19.6 0.0 0.00079 19.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KIK45964.1 - 0.0084 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase JAKMIP_CC3 PF16034.5 KIK45964.1 - 0.054 13.4 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 JAKMIP CC3 domain PTPlike_phytase PF14566.6 KIK45964.1 - 0.055 13.6 0.0 0.14 12.3 0.0 1.6 2 0 0 2 2 2 0 Inositol hexakisphosphate OSCP PF00213.18 KIK45964.1 - 0.15 12.2 0.1 0.22 11.7 0.1 1.3 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit Vac14_Fig4_bd PF11916.8 KIK45965.1 - 6.8e-79 263.7 8.8 1.2e-78 262.8 8.8 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KIK45965.1 - 5e-42 142.4 0.0 7.9e-38 129.0 0.0 3.7 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KIK45965.1 - 2.5e-10 39.7 1.4 0.011 15.9 0.0 6.8 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 KIK45965.1 - 2.3e-06 28.0 0.5 6.3 7.4 0.0 6.0 4 2 2 6 6 6 1 HEAT-like repeat Cnd1 PF12717.7 KIK45965.1 - 0.00052 20.1 6.9 0.58 10.2 1.7 3.8 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 SOG2 PF10428.9 KIK45965.1 - 0.00069 18.9 6.0 0.00069 18.9 6.0 1.9 2 0 0 2 2 2 1 RAM signalling pathway protein TAF6_C PF07571.13 KIK45965.1 - 0.016 15.5 0.1 0.55 10.6 0.0 3.1 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Arm PF00514.23 KIK45965.1 - 0.13 12.3 1.0 88 3.3 0.0 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DMPK_coil PF08826.10 KIK45965.1 - 0.24 11.5 4.5 8.1 6.6 0.1 2.8 2 0 0 2 2 2 0 DMPK coiled coil domain like ParcG PF10274.9 KIK45965.1 - 1.8 8.7 6.0 2.8 8.0 0.2 3.4 4 0 0 4 4 4 0 Parkin co-regulated protein GatB_N PF02934.15 KIK45966.1 - 3.9e-106 354.4 0.0 4.9e-106 354.1 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KIK45966.1 - 2.5e-31 108.6 0.0 3.6e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 GatB domain PAP_central PF04928.17 KIK45968.1 - 1.8e-109 364.5 0.0 2.4e-109 364.1 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KIK45968.1 - 4.1e-56 189.3 0.0 6.3e-56 188.7 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KIK45968.1 - 6.7e-13 48.8 0.0 1.7e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KIK45968.1 - 0.01 15.9 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Beta_helix PF13229.6 KIK45969.1 - 4.5e-12 46.1 25.3 2.1e-10 40.7 22.8 2.7 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 KIK45969.1 - 5.9e-05 22.5 15.6 0.027 13.7 15.7 2.5 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Glycophorin_A PF01102.18 KIK45969.1 - 0.16 12.2 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A Beta-lactamase PF00144.24 KIK45971.1 - 4.1e-41 141.3 0.1 7e-41 140.5 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase Uds1 PF15456.6 KIK45972.1 - 1.6e-30 105.9 10.2 1.6e-30 105.9 10.2 5.8 4 2 2 6 6 6 2 Up-regulated During Septation WD40 PF00400.32 KIK45974.1 - 0.49 11.4 0.6 0.49 11.4 0.6 2.5 2 1 0 2 2 2 0 WD domain, G-beta repeat EamA PF00892.20 KIK45976.1 - 4.8e-26 91.6 32.0 1.4e-15 57.7 10.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KIK45976.1 - 0.00031 20.2 20.7 0.012 15.0 7.5 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family DMT_YdcZ PF04657.13 KIK45976.1 - 0.013 15.8 9.2 0.013 15.8 9.2 2.5 2 0 0 2 2 2 0 Putative inner membrane exporter, YdcZ RseC_MucC PF04246.12 KIK45976.1 - 0.034 14.1 1.4 0.034 14.1 1.4 3.2 3 1 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DUF2070 PF09843.9 KIK45976.1 - 0.27 9.5 26.7 0.084 11.2 7.9 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) VIR_N PF15912.5 KIK45978.1 - 0.16 11.6 8.2 0.1 12.2 1.4 2.8 2 1 0 2 2 2 0 Virilizer, N-terminal MyTH4 PF00784.17 KIK45980.1 - 0.098 13.2 0.1 0.47 11.0 0.0 1.8 1 1 1 2 2 2 0 MyTH4 domain ORMDL PF04061.14 KIK45981.1 - 1.2e-53 180.6 4.3 1.5e-53 180.3 4.3 1.1 1 0 0 1 1 1 1 ORMDL family THF_DHG_CYH PF00763.23 KIK45982.1 - 6e-23 81.3 0.0 9.5e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KIK45982.1 - 4.9e-17 61.7 0.1 7.9e-09 35.0 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain OCD_Mu_crystall PF02423.15 KIK45982.1 - 0.034 13.1 0.0 0.048 12.6 0.0 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KIK45982.1 - 0.061 13.4 0.0 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase IPP-2 PF04979.14 KIK45983.1 - 7.9e-17 62.2 2.7 1.6e-16 61.2 2.7 1.5 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) SPX PF03105.19 KIK45983.1 - 2.6 7.9 10.4 3.1 7.6 10.4 1.1 1 0 0 1 1 1 0 SPX domain AAA PF00004.29 KIK45984.1 - 3.9e-55 185.9 0.0 7.4e-40 136.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK45984.1 - 1e-10 42.0 0.1 4.1e-05 23.9 0.0 3.7 2 2 1 3 3 3 1 AAA domain AAA_16 PF13191.6 KIK45984.1 - 8.3e-09 36.0 0.4 0.0042 17.5 0.0 3.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_lid_3 PF17862.1 KIK45984.1 - 5.2e-08 32.6 0.1 1.1e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KIK45984.1 - 9.2e-07 29.1 0.7 5e-05 23.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KIK45984.1 - 1.1e-06 28.8 0.0 0.048 13.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 KIK45984.1 - 3e-06 27.1 0.1 0.045 13.5 0.1 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KIK45984.1 - 4.5e-06 26.1 0.0 0.031 13.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain Mg_chelatase PF01078.21 KIK45984.1 - 5.9e-06 25.8 0.1 0.01 15.3 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.17 KIK45984.1 - 5.9e-06 26.0 0.9 5.6e-05 22.8 0.1 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.6 KIK45984.1 - 6.7e-06 26.7 0.0 0.032 14.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 KIK45984.1 - 3.4e-05 23.9 0.0 0.0031 17.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 KIK45984.1 - 8.2e-05 22.6 0.0 0.069 13.2 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KIK45984.1 - 0.00019 21.2 0.0 0.48 10.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KIK45984.1 - 0.00026 20.8 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KIK45984.1 - 0.00026 21.3 0.0 0.24 11.8 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 KIK45984.1 - 0.00041 20.4 0.0 0.2 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIK45984.1 - 0.00044 19.9 2.1 1.8 8.1 0.1 4.0 3 1 1 4 4 4 1 AAA domain ATPase PF06745.13 KIK45984.1 - 0.00046 19.6 0.1 0.019 14.3 0.1 2.5 2 0 0 2 2 2 1 KaiC AAA_7 PF12775.7 KIK45984.1 - 0.00053 19.5 0.0 0.041 13.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 KIK45984.1 - 0.0007 18.8 0.0 0.52 9.5 0.1 2.3 2 0 0 2 2 2 2 NB-ARC domain Parvo_NS1 PF01057.17 KIK45984.1 - 0.00073 18.7 0.0 0.81 8.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 KIK45984.1 - 0.00088 19.0 0.0 0.45 10.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_11 PF13086.6 KIK45984.1 - 0.001 18.9 0.0 0.086 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 KIK45984.1 - 0.0014 18.1 0.0 0.47 9.8 0.0 3.1 2 1 0 2 2 2 1 Bacterial TniB protein T2SSE PF00437.20 KIK45984.1 - 0.0017 17.5 0.0 1.5 7.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein NACHT PF05729.12 KIK45984.1 - 0.0023 17.9 3.2 2.8 7.8 0.1 3.7 4 0 0 4 4 3 1 NACHT domain Hydin_ADK PF17213.3 KIK45984.1 - 0.0061 16.9 0.2 2 8.7 0.0 2.4 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain ABC_tran PF00005.27 KIK45984.1 - 0.0071 16.9 0.1 0.089 13.3 0.1 2.4 2 0 0 2 2 2 1 ABC transporter ResIII PF04851.15 KIK45984.1 - 0.0082 16.2 0.0 0.17 11.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 KIK45984.1 - 0.0083 16.0 0.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KIK45984.1 - 0.012 14.9 0.1 0.32 10.2 0.1 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 KIK45984.1 - 0.013 15.8 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIK45984.1 - 0.018 14.7 0.0 0.27 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 KIK45984.1 - 0.026 14.4 0.1 2.6 7.8 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 KIK45984.1 - 0.039 13.2 0.0 7.7 5.7 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_19 PF13245.6 KIK45984.1 - 0.045 14.1 0.3 0.93 9.8 0.1 2.6 3 0 0 3 3 2 0 AAA domain KTI12 PF08433.10 KIK45984.1 - 0.046 13.2 0.0 3.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 PhoH PF02562.16 KIK45984.1 - 0.059 12.8 0.0 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein CDC48_N PF02359.18 KIK45984.1 - 0.1 12.8 0.0 0.74 10.0 0.0 2.5 2 0 0 2 2 1 0 Cell division protein 48 (CDC48), N-terminal domain STIMATE PF12400.8 KIK45985.1 - 7.5e-33 113.7 9.1 1.4e-29 103.2 3.4 2.4 1 1 1 2 2 2 2 STIMATE family Sec62 PF03839.16 KIK45985.1 - 0.78 9.2 6.5 1.6 8.1 6.5 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2009 PF09418.10 KIK45986.1 - 9.1e-214 710.7 0.0 1.1e-213 710.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) CEBP_ZZ PF16366.5 KIK45986.1 - 0.02 15.1 2.3 0.052 13.8 2.3 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-B_box PF00643.24 KIK45986.1 - 0.037 14.2 7.0 0.18 12.0 7.0 2.0 1 1 0 1 1 1 0 B-box zinc finger Fez1 PF06818.15 KIK45986.1 - 0.074 13.5 1.0 0.12 12.9 0.1 1.6 2 0 0 2 2 2 0 Fez1 F-box-like PF12937.7 KIK45987.1 - 0.0001 22.1 0.5 0.0001 22.1 0.5 2.3 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIK45988.1 - 0.027 14.4 2.0 0.13 12.1 0.8 2.5 2 0 0 2 2 2 0 F-box-like ICMT PF04140.14 KIK45989.1 - 4.8e-15 55.7 0.2 2.4e-13 50.3 0.1 2.3 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK45989.1 - 8.6e-12 45.4 1.2 1e-10 41.9 0.9 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIK45989.1 - 5e-11 42.0 0.0 6.8e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family CAAD PF14159.6 KIK45989.1 - 0.032 14.1 0.1 0.074 12.9 0.1 1.6 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF1295 PF06966.12 KIK45989.1 - 0.038 13.5 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Sigma70_r4_2 PF08281.12 KIK45990.1 - 0.031 13.9 3.9 0.66 9.7 0.0 3.7 3 0 0 3 3 3 0 Sigma-70, region 4 CSTF_C PF14304.6 KIK45990.1 - 0.32 10.6 12.0 2.6 7.7 0.0 4.3 4 0 0 4 4 4 0 Transcription termination and cleavage factor C-terminal ICMT PF04140.14 KIK45991.1 - 1.2e-15 57.7 0.9 7.3e-14 52.0 0.1 2.4 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK45991.1 - 1.1e-12 48.3 2.2 3e-12 46.9 0.3 2.3 3 0 0 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIK45991.1 - 1.8e-08 33.6 0.2 3e-08 32.9 0.0 1.4 2 0 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KIK45991.1 - 0.049 13.2 0.1 0.077 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Taq-exonuc PF09281.10 KIK45991.1 - 0.053 13.5 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 Taq polymerase, exonuclease Pro-kuma_activ PF09286.11 KIK45992.1 - 2.9e-40 137.9 0.1 4.3e-40 137.3 0.1 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Stn1 PF10451.9 KIK45992.1 - 0.082 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Telomere regulation protein Stn1 Pro-kuma_activ PF09286.11 KIK45995.1 - 2.9e-36 124.9 0.1 4.8e-36 124.2 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIK45995.1 - 0.0027 17.0 1.5 0.007 15.7 1.5 1.6 1 0 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.11 KIK45996.1 - 1.7e-37 128.9 0.0 2.7e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Stn1 PF10451.9 KIK45996.1 - 0.087 11.8 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Telomere regulation protein Stn1 Peptidase_M44 PF03410.13 KIK45996.1 - 0.27 9.8 0.0 0.37 9.3 0.0 1.1 1 0 0 1 1 1 0 Metallopeptidase from vaccinia pox Hep_59 PF07052.11 KIK45998.1 - 5.4e-26 91.4 2.4 5.4e-26 91.4 2.4 2.6 2 1 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 DUF1258 PF06869.12 KIK45998.1 - 0.082 12.4 0.6 9.1 5.7 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1258) DLIC PF05783.11 KIK46000.1 - 0.03 13.2 8.3 0.061 12.2 7.5 1.7 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) PMI_typeI PF01238.21 KIK46002.1 - 6.7e-89 298.7 0.0 8e-89 298.4 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 KIK46002.1 - 5.6e-05 22.8 2.1 0.012 15.4 0.4 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KIK46002.1 - 0.02 14.6 0.5 0.063 13.0 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Ribosomal_L44 PF00935.19 KIK46003.1 - 1.2e-37 128.2 11.7 2.1e-37 127.5 11.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 Cathelicidins PF00666.17 KIK46003.1 - 0.019 15.3 0.7 0.035 14.4 0.7 1.4 1 0 0 1 1 1 0 Cathelicidin NACHT PF05729.12 KIK46005.1 - 2.3e-10 40.6 0.3 8.3e-10 38.8 0.3 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIK46005.1 - 3.7e-07 30.7 1.5 6.7e-07 29.8 0.2 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KIK46005.1 - 5.3e-07 30.1 0.0 1.2e-06 29.0 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KIK46005.1 - 0.0001 22.2 0.1 0.099 12.6 0.2 3.5 3 1 0 3 3 3 1 NTPase AAA_22 PF13401.6 KIK46005.1 - 0.0011 19.2 0.0 0.023 15.0 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 KIK46005.1 - 0.0095 16.5 0.1 0.045 14.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KIK46005.1 - 0.0098 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain KAP_NTPase PF07693.14 KIK46005.1 - 0.016 14.4 1.9 0.44 9.7 0.2 2.3 1 1 0 2 2 2 0 KAP family P-loop domain APS_kinase PF01583.20 KIK46005.1 - 0.03 14.2 0.1 0.058 13.3 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 KIK46005.1 - 0.077 12.2 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain TsaE PF02367.17 KIK46005.1 - 0.098 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KIK46005.1 - 0.19 11.3 0.1 0.45 10.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KIK46005.1 - 0.2 12.0 0.0 0.5 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase SafA PF17073.5 KIK46006.1 - 0.24 11.4 2.8 0.68 9.9 2.8 1.8 1 0 0 1 1 1 0 Two-component-system connector protein His_Phos_2 PF00328.22 KIK46007.1 - 8.5e-16 58.3 0.1 3.3e-08 33.3 0.0 2.4 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Scramblase PF03803.15 KIK46008.1 - 6.8e-56 189.0 0.0 2.1e-55 187.4 0.0 1.7 1 1 0 1 1 1 1 Scramblase ADH_zinc_N PF00107.26 KIK46010.1 - 1.1e-15 57.8 0.0 1.7e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK46010.1 - 1.5e-14 53.8 0.6 2.9e-14 52.9 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KIK46010.1 - 4e-11 42.8 0.0 5.5e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KIK46010.1 - 3.5e-06 28.1 0.0 6e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KIK46010.1 - 0.00062 19.1 0.9 0.00088 18.6 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain Staph_opine_DH PF10100.9 KIK46010.1 - 0.051 12.2 0.0 0.066 11.9 0.0 1.1 1 0 0 1 1 1 0 Staphylopine dehydrogenase Pyr_redox_2 PF07992.14 KIK46010.1 - 0.057 12.6 0.1 0.36 10.0 0.1 2.0 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N PF08240.12 KIK46011.1 - 1.9e-32 111.4 2.3 3.3e-32 110.6 2.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK46011.1 - 3.6e-15 56.1 0.0 6.1e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIK46011.1 - 6.2e-10 38.9 0.0 9e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KIK46011.1 - 3.5e-05 24.9 0.0 6.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KIK46011.1 - 0.00059 19.2 0.9 0.00083 18.7 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain Staph_opine_DH PF10100.9 KIK46011.1 - 0.016 13.8 0.0 0.022 13.4 0.0 1.1 1 0 0 1 1 1 0 Staphylopine dehydrogenase ADH_N_2 PF16884.5 KIK46011.1 - 0.084 12.8 0.0 0.44 10.5 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Sacchrp_dh_NADP PF03435.18 KIK46011.1 - 0.14 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_3 PF03447.16 KIK46011.1 - 0.17 12.6 0.0 0.3 11.7 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Peptidase_S9 PF00326.21 KIK46012.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KIK46012.1 - 0.0025 17.5 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK46012.1 - 0.031 13.6 0.0 0.056 12.7 0.0 1.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KIK46012.1 - 0.037 14.1 0.0 0.059 13.5 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_1 PF00561.20 KIK46013.1 - 0.0036 17.0 0.0 0.0051 16.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK46013.1 - 0.036 13.5 0.0 0.095 12.2 0.0 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KIK46013.1 - 0.049 13.7 0.0 0.097 12.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Hydrolase_4 PF12146.8 KIK46013.1 - 0.082 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lactamase_B PF00753.27 KIK46014.1 - 0.097 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily FYVE_2 PF02318.16 KIK46014.1 - 0.17 12.1 7.6 1.2 9.4 2.5 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger zinc_ribbon_4 PF13717.6 KIK46014.1 - 9.2 6.3 9.0 0.53 10.3 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon domain TBCC PF07986.12 KIK46019.1 - 5.7e-25 87.4 0.4 9.8e-25 86.6 0.4 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KIK46019.1 - 1.2e-09 38.6 2.6 6.2e-09 36.3 0.8 2.2 2 0 0 2 2 2 1 Tubulin-specific chaperone C N-terminal domain CDC45 PF02724.14 KIK46020.1 - 0.14 10.4 0.0 0.14 10.4 0.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 KIK46022.1 - 4.1e-19 69.0 0.0 8.2e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KIK46022.1 - 1.2e-13 51.2 13.8 1.6e-07 31.9 0.8 6.1 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT PF02985.22 KIK46022.1 - 3.7e-12 45.4 14.2 0.00067 19.7 0.1 6.3 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.6 KIK46022.1 - 1.8e-09 37.9 1.2 0.0013 19.1 0.6 4.4 2 2 1 4 4 4 2 HEAT repeats Pkinase_Tyr PF07714.17 KIK46022.1 - 5.6e-09 35.6 0.0 3e-08 33.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.7 KIK46022.1 - 0.007 16.4 4.7 0.93 9.5 0.3 3.7 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KIK46022.1 - 0.034 14.6 5.2 0.28 11.8 0.3 3.9 3 0 0 3 3 3 0 HEAT-like repeat Cohesin_HEAT PF12765.7 KIK46022.1 - 1.4 9.3 12.6 0.77 10.1 0.1 3.7 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion tRNA-synt_2b PF00587.25 KIK46023.1 - 4.2e-36 124.6 0.0 7.5e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KIK46023.1 - 8.1e-17 61.2 0.1 2.3e-16 59.7 0.1 1.8 2 0 0 2 2 2 1 Anticodon binding domain TGS PF02824.21 KIK46023.1 - 6.8e-14 51.7 0.0 1.3e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 KIK46023.1 - 3.7e-12 46.2 0.0 7.6e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain CSTF2_hinge PF14327.6 KIK46024.1 - 1.8e-29 102.0 2.4 5.7e-29 100.4 2.4 1.9 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KIK46024.1 - 3.4e-22 78.0 0.1 8.7e-22 76.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KIK46024.1 - 4.2e-14 51.9 3.1 1.4e-13 50.2 3.1 1.9 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 KIK46024.1 - 0.021 15.0 0.0 0.071 13.2 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif UBM PF14377.6 KIK46024.1 - 0.048 13.1 4.4 0.51 9.9 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin binding region HSP20 PF00011.21 KIK46025.1 - 1.4e-12 47.6 0.0 2.4e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIK46025.1 - 0.025 14.1 0.0 0.081 12.5 0.0 1.8 1 1 0 1 1 1 0 HSP20-like domain found in ArsA Fungal_trans PF04082.18 KIK46027.1 - 3.2e-12 46.0 0.1 6e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2607 PF10795.9 KIK46027.1 - 0.013 15.6 0.1 0.046 13.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) Fungal_trans PF04082.18 KIK46029.1 - 3.2e-11 42.8 0.1 5.2e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK46029.1 - 0.00013 22.0 12.8 0.00025 21.1 12.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SNF5 PF04855.12 KIK46032.1 - 6e-65 219.4 3.4 1.1e-64 218.4 3.4 1.4 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Peptidase_M20 PF01546.28 KIK46035.1 - 4.2e-08 33.1 0.1 6.6e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIK46035.1 - 1.6e-06 28.0 0.1 3.7e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF1905 PF08922.11 KIK46035.1 - 0.11 12.6 0.0 0.39 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1905) adh_short PF00106.25 KIK46036.1 - 1e-27 96.9 0.0 1.7e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK46036.1 - 3.2e-22 79.2 0.0 1.6e-21 77.0 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 KIK46036.1 - 0.024 14.5 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.15 KIK46036.1 - 0.039 13.9 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 YjeF-related protein N-terminus NmrA PF05368.13 KIK46036.1 - 0.13 11.7 0.1 2.2 7.8 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family Tubulin PF00091.25 KIK46036.1 - 0.16 12.1 1.1 0.27 11.4 0.4 1.7 2 0 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain UcrQ PF02939.16 KIK46037.1 - 7.1e-28 96.4 1.4 8e-28 96.2 1.4 1.0 1 0 0 1 1 1 1 UcrQ family RolB_RolC PF02027.17 KIK46037.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 RolB/RolC glucosidase family zf-SCNM1 PF15803.5 KIK46039.1 - 0.04 13.5 0.8 0.078 12.6 0.8 1.5 1 0 0 1 1 1 0 Zinc-finger of sodium channel modifier 1 AAA_11 PF13086.6 KIK46042.1 - 1.7e-65 221.4 0.3 1.7e-65 221.4 0.3 2.5 2 1 0 2 2 1 1 AAA domain AAA_12 PF13087.6 KIK46042.1 - 1.4e-52 178.3 0.0 2.5e-52 177.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KIK46042.1 - 6e-11 42.5 0.1 0.011 15.4 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KIK46042.1 - 4.9e-10 39.4 1.0 4.2e-06 26.6 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KIK46042.1 - 2.6e-08 34.3 0.0 9.4e-08 32.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KIK46042.1 - 5.6e-06 26.5 0.0 8.5e-05 22.6 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIK46042.1 - 6.3e-06 26.5 0.3 0.00042 20.6 0.3 2.6 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KIK46042.1 - 4e-05 23.0 0.4 0.065 12.5 0.0 2.8 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 KIK46042.1 - 0.0012 19.3 2.6 0.0014 19.2 0.0 2.5 2 0 0 2 2 2 1 ABC transporter PhoH PF02562.16 KIK46042.1 - 0.0036 16.8 0.0 0.15 11.5 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.29 KIK46042.1 - 0.0055 17.1 0.1 0.041 14.3 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 KIK46042.1 - 0.0056 16.3 5.1 0.018 14.6 5.1 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 KIK46042.1 - 0.0058 16.4 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_24 PF13479.6 KIK46042.1 - 0.0091 15.7 0.0 0.24 11.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK46042.1 - 0.017 15.5 0.1 0.072 13.5 0.1 2.3 1 1 0 1 1 1 0 AAA ATPase domain PIF1 PF05970.14 KIK46042.1 - 0.027 13.7 0.0 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase IstB_IS21 PF01695.17 KIK46042.1 - 0.055 13.2 0.1 0.6 9.8 0.0 2.5 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_25 PF13481.6 KIK46042.1 - 0.063 12.8 0.0 0.54 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KIK46042.1 - 0.14 12.6 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Nop53 PF07767.11 KIK46042.1 - 2.6 7.4 17.1 0.24 10.8 10.5 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) ATPase_2 PF01637.18 KIK46043.1 - 2.1e-14 54.0 0.0 3.9e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KIK46043.1 - 3.6e-05 24.2 0.1 0.0003 21.2 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK46043.1 - 0.00067 19.9 0.0 2.2 8.5 0.0 2.9 3 1 0 3 3 3 2 AAA domain AAA PF00004.29 KIK46043.1 - 0.005 17.3 0.0 1.4 9.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA12 PF10443.9 KIK46043.1 - 0.008 15.0 0.0 0.017 13.9 0.0 1.6 2 0 0 2 2 2 1 RNA12 protein AAA_14 PF13173.6 KIK46043.1 - 0.011 15.8 0.0 0.72 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KIK46043.1 - 0.032 14.2 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KIK46043.1 - 0.098 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 KIK46043.1 - 0.18 11.7 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase zf-C3HC4_2 PF13923.6 KIK46045.1 - 1.9e-09 37.2 2.1 1.9e-09 37.2 2.1 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK46045.1 - 2.5e-08 33.7 5.0 2.5e-08 33.7 5.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK46045.1 - 2.6e-08 33.6 10.8 5.9e-08 32.4 4.4 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK46045.1 - 3.1e-08 33.5 1.4 3.1e-08 33.5 1.4 2.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIK46045.1 - 3.2e-06 27.4 8.5 3.2e-06 27.4 8.5 2.8 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KIK46045.1 - 1.1e-05 25.3 4.0 1.1e-05 25.3 4.0 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KIK46045.1 - 0.00065 19.8 6.1 0.00065 19.8 6.1 3.2 2 2 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KIK46045.1 - 0.00075 19.3 0.3 0.00075 19.3 0.3 2.2 2 1 0 2 2 2 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KIK46045.1 - 0.00089 19.1 4.1 0.00089 19.1 4.1 2.9 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KIK46045.1 - 0.0069 16.0 0.7 0.0069 16.0 0.7 3.0 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type zf-MIZ PF02891.20 KIK46045.1 - 0.047 13.4 1.6 0.047 13.4 1.6 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Pellino PF04710.14 KIK46045.1 - 0.052 12.2 0.3 0.066 11.9 0.3 1.1 1 0 0 1 1 1 0 Pellino zf-UBR PF02207.20 KIK46045.1 - 0.071 13.3 0.1 0.071 13.3 0.1 2.3 2 1 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Tmpp129 PF10272.9 KIK46045.1 - 0.22 10.8 2.6 0.31 10.3 2.6 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor GAGA PF09237.11 KIK46045.1 - 0.24 11.2 2.2 1.8 8.5 0.3 2.3 2 0 0 2 2 2 0 GAGA factor Sec2p PF06428.11 KIK46045.1 - 0.35 10.9 1.1 0.49 10.4 1.1 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p zf-RING_11 PF17123.5 KIK46045.1 - 0.38 10.5 5.8 0.37 10.6 2.6 2.4 2 0 0 2 2 2 0 RING-like zinc finger DZR PF12773.7 KIK46045.1 - 2.2 8.4 11.2 15 5.7 0.2 3.1 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.6 KIK46045.1 - 2.2 8.2 16.7 7.2 6.5 2.0 2.8 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_SprT PF17283.2 KIK46045.1 - 5.5 7.0 13.0 0.61 10.0 0.9 3.5 4 0 0 4 4 3 0 SprT-like zinc ribbon domain zf-rbx1 PF12678.7 KIK46045.1 - 6.1 7.2 11.0 0.15 12.4 3.9 2.0 2 1 0 2 2 1 0 RING-H2 zinc finger domain TPT PF03151.16 KIK46047.1 - 8.5e-35 120.5 14.1 1.4e-34 119.8 14.1 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KIK46047.1 - 1.3e-06 27.9 12.9 0.00018 20.9 4.2 2.1 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.20 KIK46047.1 - 1.4e-05 25.3 31.6 0.0035 17.5 12.6 3.2 2 2 1 3 3 3 2 EamA-like transporter family YjcB PF15940.5 KIK46048.1 - 0.03 14.5 0.0 0.041 14.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function ApbA PF02558.16 KIK46049.1 - 1.1e-19 70.6 0.0 1.8e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KIK46049.1 - 1.9e-18 66.8 0.0 1.2e-17 64.3 0.0 2.1 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Piwi PF02171.17 KIK46052.1 - 1.1e-81 274.4 0.0 1.4e-81 274.0 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KIK46052.1 - 7.4e-24 84.9 0.0 1.6e-23 83.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KIK46052.1 - 1.1e-19 69.8 0.3 2.4e-19 68.7 0.3 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 KIK46052.1 - 1e-14 54.5 0.0 1.7e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KIK46052.1 - 3.7e-13 49.6 1.9 1.5e-11 44.5 0.1 3.2 3 0 0 3 3 3 1 Argonaute linker 2 domain ArgoMid PF16487.5 KIK46052.1 - 0.0006 20.0 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute M20_dimer PF07687.14 KIK46055.1 - 4.9e-09 36.1 0.0 9.8e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KIK46055.1 - 1.6e-06 27.9 0.2 2.5e-06 27.4 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Promethin PF16015.5 KIK46056.1 - 3.8e-06 26.8 14.5 5.9e-06 26.2 14.5 1.2 1 0 0 1 1 1 1 Promethin DUF2070 PF09843.9 KIK46056.1 - 0.53 8.5 9.0 0.65 8.2 9.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TMEMspv1-c74-12 PF11044.8 KIK46056.1 - 9.3 6.3 12.1 0.2 11.6 2.2 2.8 3 0 0 3 3 3 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein RNA_pol_Rpc34 PF05158.12 KIK46057.1 - 3e-79 266.8 7.0 3.6e-67 227.1 0.4 2.4 2 1 0 2 2 2 2 RNA polymerase Rpc34 subunit LT-IIB PF06453.11 KIK46057.1 - 0.11 12.4 0.0 0.61 10.0 0.0 2.0 1 1 1 2 2 2 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) TFIIF_alpha PF05793.12 KIK46057.1 - 0.46 9.0 83.1 0.67 8.5 83.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TPR_12 PF13424.6 KIK46058.1 - 1.5e-06 28.4 4.3 0.84 10.0 1.2 4.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 KIK46058.1 - 5.4e-06 26.1 9.8 0.12 12.3 0.8 5.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK46058.1 - 0.0015 19.1 1.8 34 5.6 0.2 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK46058.1 - 0.0057 16.4 3.0 39 4.3 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK46058.1 - 0.0088 16.1 4.5 7.7 6.9 0.0 4.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK46058.1 - 0.044 13.5 0.0 1.9 8.2 0.0 3.3 4 0 0 4 4 4 0 TPR repeat TPR_7 PF13176.6 KIK46058.1 - 0.14 12.2 5.8 6.6 7.0 1.1 4.8 5 2 0 5 5 5 0 Tetratricopeptide repeat CRISPR_Cse2 PF09485.10 KIK46058.1 - 0.18 12.4 3.3 5.3 7.6 3.3 2.6 1 1 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) GDP_Man_Dehyd PF16363.5 KIK46060.1 - 2.3e-155 517.0 0.0 2.6e-155 516.9 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIK46060.1 - 1.2e-68 231.2 0.0 1.5e-68 230.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIK46060.1 - 0.0022 17.2 0.0 0.0034 16.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Aldo_ket_red PF00248.21 KIK46061.1 - 9.2e-37 126.8 0.0 2.1e-35 122.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Lipid_DES PF08557.10 KIK46064.1 - 0.12 11.8 0.3 0.24 10.9 0.3 1.4 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) Thiolase_N PF00108.23 KIK46065.1 - 0.34 10.2 1.9 4.7 6.5 0.2 2.7 2 1 1 3 3 3 0 Thiolase, N-terminal domain Plavaka PF18759.1 KIK46066.1 - 1.4e-34 119.8 0.0 2.3e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase XPB_DRD PF18458.1 KIK46066.1 - 0.0033 17.3 0.0 0.0072 16.2 0.0 1.6 1 0 0 1 1 1 1 Xeroderma pigmentosum group B helicase damage recognition domain Nop14 PF04147.12 KIK46066.1 - 4 5.5 16.2 5.6 5.0 16.2 1.1 1 0 0 1 1 1 0 Nop14-like family SeqA_N PF17206.3 KIK46067.1 - 0.056 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 SeqA protein N-terminal domain DUF3085 PF11284.8 KIK46069.1 - 0.047 14.0 0.0 0.065 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) Gsf2 PF11055.8 KIK46069.1 - 0.14 10.9 0.0 0.15 10.8 0.0 1.0 1 0 0 1 1 1 0 Glucose signalling factor 2 A_deaminase PF00962.22 KIK46070.1 - 3.5e-09 36.4 0.0 4.4e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Thg1 PF04446.12 KIK46072.1 - 0.012 15.6 0.1 0.67 10.0 0.0 2.6 2 0 0 2 2 2 0 tRNAHis guanylyltransferase HGWP PF03578.15 KIK46072.1 - 0.068 12.7 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 HGWP repeat G-alpha PF00503.20 KIK46079.1 - 3.7e-101 338.8 0.0 4.7e-101 338.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK46079.1 - 5e-12 45.6 1.1 5.9e-08 32.4 0.6 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIK46079.1 - 0.0073 16.4 0.1 0.76 9.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KIK46079.1 - 0.025 14.8 0.3 6 7.1 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KIK46079.1 - 0.058 12.7 5.6 0.34 10.2 0.2 2.8 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region AAA_21 PF13304.6 KIK46079.1 - 0.06 13.2 0.0 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KIK46079.1 - 0.15 12.6 0.0 0.27 11.7 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KIK46079.1 - 0.19 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ANAPC4_WD40 PF12894.7 KIK46083.1 - 4.3e-09 36.5 0.0 0.023 15.0 0.2 5.2 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK46083.1 - 1.9e-07 31.6 0.6 1.5 9.8 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KIK46083.1 - 0.037 13.1 0.0 0.096 11.7 0.0 1.5 2 0 0 2 2 2 0 Coatomer WD associated region DUF2415 PF10313.9 KIK46083.1 - 0.08 12.9 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) SPO22 PF08631.10 KIK46084.1 - 1.8e-56 191.7 17.9 1.9e-56 191.6 6.3 3.6 3 1 1 4 4 4 3 Meiosis protein SPO22/ZIP4 like Nod1 PF17114.5 KIK46084.1 - 0.37 10.9 3.6 20 5.3 0.1 3.5 4 0 0 4 4 4 0 Gef2-related medial cortical node protein Nod1 DUF1761 PF08570.10 KIK46085.1 - 0.057 13.7 0.1 0.065 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) Gly-zipper_YMGG PF13441.6 KIK46085.1 - 0.07 12.9 0.8 0.11 12.3 0.8 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Cyclin PF08613.11 KIK46086.1 - 5.3e-13 49.6 0.3 1.1e-12 48.6 0.0 1.6 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KIK46086.1 - 3.4e-09 36.5 0.0 5.8e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Chs7 PF12271.8 KIK46088.1 - 1.2e-115 385.8 23.1 1.4e-115 385.6 23.1 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone RAMP4 PF06624.12 KIK46088.1 - 0.066 13.3 0.2 0.19 11.8 0.2 1.7 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 Abhydrolase_2 PF02230.16 KIK46090.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF632 PF04782.12 KIK46090.1 - 0.11 11.7 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF632) Peptidase_U4 PF03419.13 KIK46092.1 - 0.0052 16.1 7.3 0.0088 15.4 7.3 1.4 1 0 0 1 1 1 1 Sporulation factor SpoIIGA SecG PF03840.14 KIK46092.1 - 0.024 14.7 5.1 0.024 14.7 5.1 2.2 2 0 0 2 2 2 0 Preprotein translocase SecG subunit JTB PF05439.12 KIK46092.1 - 0.12 12.4 2.0 0.17 11.9 0.7 1.8 1 1 1 2 2 2 0 Jumping translocation breakpoint protein (JTB) DUF624 PF04854.14 KIK46092.1 - 4.9 7.3 9.0 2.7 8.2 4.4 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF624 Cullin PF00888.22 KIK46093.1 - 9e-142 473.8 4.0 1.3e-141 473.2 4.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KIK46093.1 - 3.3e-25 87.9 0.9 1.3e-24 86.0 0.9 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF515 PF04415.12 KIK46093.1 - 0.00035 19.1 1.9 0.00057 18.4 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF515) Med21 PF11221.8 KIK46094.1 - 3.5e-26 92.2 10.5 4.6e-26 91.8 10.5 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med30 PF11315.8 KIK46094.1 - 0.015 15.5 2.8 0.029 14.6 1.0 1.9 2 0 0 2 2 2 0 Mediator complex subunit 30 DUF3391 PF11871.8 KIK46094.1 - 0.068 13.7 2.8 0.11 13.1 2.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) SbsC_C PF18058.1 KIK46094.1 - 0.074 13.3 0.9 0.12 12.7 0.7 1.5 1 1 0 1 1 1 0 SbsC C-terminal domain FUSC PF04632.12 KIK46094.1 - 0.26 9.8 1.1 0.26 9.8 0.1 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family TssO PF17561.2 KIK46094.1 - 0.31 11.2 3.5 0.26 11.4 0.9 1.8 2 0 0 2 2 2 0 Type VI secretion system, TssO Med11 PF10280.9 KIK46094.1 - 0.75 10.3 6.7 4.4 7.8 6.7 1.9 1 1 0 1 1 1 0 Mediator complex protein PhoU PF01895.19 KIK46094.1 - 1.2 9.6 6.2 5.5 7.5 0.5 2.9 2 1 1 3 3 3 0 PhoU domain Sugarporin_N PF11471.8 KIK46094.1 - 2.3 8.2 5.7 0.48 10.4 1.9 1.8 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension ZapB PF06005.12 KIK46094.1 - 2.5 8.6 9.1 23 5.5 4.1 2.4 2 0 0 2 2 2 0 Cell division protein ZapB SseC PF04888.12 KIK46094.1 - 5.3 6.5 6.1 13 5.2 2.1 2.1 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family Rtf2 PF04641.12 KIK46095.1 - 1.5e-71 240.9 0.1 1.8e-71 240.6 0.1 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 KIK46095.1 - 0.0015 18.3 0.1 2.3 8.1 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-UDP PF14569.6 KIK46095.1 - 0.078 13.1 0.4 0.26 11.4 0.4 2.0 1 1 0 1 1 1 0 Zinc-binding RING-finger MRP-S31 PF15433.6 KIK46095.1 - 0.088 12.5 1.5 0.15 11.7 1.5 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 MMR_HSR1 PF01926.23 KIK46099.1 - 1.6e-07 31.4 0.0 4.3e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KIK46099.1 - 0.00085 19.4 0.2 0.00085 19.4 0.2 1.8 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KIK46099.1 - 0.0031 17.5 0.0 0.0064 16.4 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 KIK46099.1 - 0.0058 17.1 0.2 0.017 15.6 0.0 1.9 2 0 0 2 2 2 1 ABC transporter DUF815 PF05673.13 KIK46099.1 - 0.0099 15.1 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Ras PF00071.22 KIK46099.1 - 0.011 15.4 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Ras family AIG1 PF04548.16 KIK46099.1 - 0.012 15.0 0.0 0.012 15.0 0.0 1.7 2 0 0 2 2 1 0 AIG1 family Roc PF08477.13 KIK46099.1 - 0.019 15.2 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KIK46099.1 - 0.038 14.4 1.1 0.064 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KIK46099.1 - 0.1 12.9 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK46099.1 - 0.2 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DLIC PF05783.11 KIK46099.1 - 0.33 9.7 0.0 0.33 9.7 0.0 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_23 PF13476.6 KIK46099.1 - 0.59 10.6 4.6 2.1 8.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF4419 PF14388.6 KIK46101.1 - 1.9e-21 76.8 2.9 1.1e-20 74.3 2.9 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) DHC_N1 PF08385.12 KIK46102.1 - 4.9e-127 424.9 8.8 4.2e-126 421.8 4.5 2.2 2 0 0 2 2 2 2 Dynein heavy chain, N-terminal region 1 DUF4199 PF13858.6 KIK46104.1 - 0.0059 17.0 0.7 0.0068 16.8 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) ORC5_C PF14630.6 KIK46106.1 - 7.5e-61 206.1 0.0 1e-60 205.7 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus OPT PF03169.15 KIK46107.1 - 7.6e-184 612.8 63.2 8.6e-184 612.6 63.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PS_Dcarbxylase PF02666.15 KIK46109.1 - 8.7e-77 257.2 0.0 4.2e-57 192.9 0.0 3.0 3 0 0 3 3 3 3 Phosphatidylserine decarboxylase zf-ANAPC11 PF12861.7 KIK46111.1 - 6.9e-39 131.8 11.0 8e-39 131.6 11.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KIK46111.1 - 3e-22 78.6 11.0 5.2e-22 77.9 11.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KIK46111.1 - 7.9e-05 22.9 18.5 0.00027 21.2 14.4 2.7 1 1 1 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KIK46111.1 - 0.0095 16.0 9.9 0.034 14.2 9.9 1.9 1 1 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KIK46111.1 - 0.072 12.7 22.4 0.52 10.0 13.4 2.9 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KIK46111.1 - 0.13 12.3 12.4 2.7 8.1 13.2 2.7 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 KIK46111.1 - 0.28 11.1 13.5 1.4 8.8 13.5 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK46111.1 - 2.6 8.0 19.2 2 8.4 15.0 2.5 1 1 1 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIK46111.1 - 4.5 7.1 15.6 25 4.7 15.6 2.1 1 1 0 1 1 1 0 RING-like zinc finger RINGv PF12906.7 KIK46111.1 - 6.6 6.9 13.4 0.21 11.7 4.1 2.6 2 2 0 2 2 2 0 RING-variant domain FANCL_C PF11793.8 KIK46111.1 - 10 6.4 14.9 63 3.9 14.9 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain PSP1 PF04468.12 KIK46112.1 - 2.7e-30 104.5 2.8 4.3e-30 103.8 2.8 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Rgp1 PF08737.10 KIK46113.1 - 3e-54 184.8 0.0 8.2e-54 183.4 0.0 1.7 2 0 0 2 2 2 1 Rgp1 Arrestin_C PF02752.22 KIK46113.1 - 1.6e-05 25.4 0.0 1 9.8 0.0 4.2 4 0 0 4 4 4 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KIK46113.1 - 0.057 13.5 0.0 0.89 9.6 0.0 2.8 3 0 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain Toxin_29 PF08116.11 KIK46116.1 - 0.0064 16.5 9.7 0.0064 16.5 9.7 1.5 2 0 0 2 2 2 1 PhTx neurotoxin family Conotoxin_I2 PF17557.2 KIK46116.1 - 0.019 15.0 6.2 0.03 14.5 6.2 1.4 1 1 0 1 1 1 0 I2-superfamily conotoxins Fungus-induced PF10917.8 KIK46116.1 - 0.066 13.5 1.1 0.092 13.1 1.1 1.5 1 1 0 1 1 1 0 Fungus-induced protein Toxin_12 PF07740.12 KIK46116.1 - 0.11 13.2 7.2 0.17 12.6 7.2 1.3 1 0 0 1 1 1 0 Ion channel inhibitory toxin zf-MYND PF01753.18 KIK46118.1 - 2.4e-09 37.1 12.5 6e-09 35.9 12.5 1.7 1 0 0 1 1 1 1 MYND finger Y_phosphatase PF00102.27 KIK46119.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase AAA_16 PF13191.6 KIK46119.1 - 0.017 15.5 0.0 0.045 14.1 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain UvrD-helicase PF00580.21 KIK46119.1 - 0.098 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_24 PF13479.6 KIK46119.1 - 0.13 11.9 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK46119.1 - 0.17 12.1 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Alpha-amylase PF00128.24 KIK46120.1 - 4.4e-55 187.6 0.0 6.4e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KIK46120.1 - 5.1e-13 49.1 0.0 9.8e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.6 KIK46120.1 - 0.065 12.3 0.0 0.095 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Glyco_transf_25 PF01755.17 KIK46121.1 - 3.4e-10 40.1 0.0 1.1e-08 35.3 0.0 2.6 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Melibiase_C PF17801.1 KIK46121.1 - 0.092 12.8 0.2 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 Alpha galactosidase C-terminal beta sandwich domain MFS_1 PF07690.16 KIK46122.1 - 4.9e-38 131.0 21.7 4.9e-38 131.0 21.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK46122.1 - 1.4e-15 57.1 2.8 1.4e-15 57.1 2.8 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KIK46122.1 - 0.0033 15.9 1.3 0.0064 15.0 1.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) His_Phos_1 PF00300.22 KIK46124.1 - 4.6e-34 117.8 0.0 7.6e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Herpes_US9 PF06072.11 KIK46125.1 - 6.2 6.8 7.6 3.9 7.4 0.4 3.1 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 adh_short PF00106.25 KIK46126.1 - 1.6e-24 86.4 0.0 5.7e-24 84.7 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK46126.1 - 4e-14 52.7 0.2 5.4e-12 45.8 0.2 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK46126.1 - 7.2e-09 35.8 2.7 1.8e-07 31.2 0.4 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KIK46126.1 - 0.014 14.9 0.0 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DFP PF04127.15 KIK46126.1 - 0.056 13.3 0.1 0.17 11.7 0.1 1.7 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Glyco_tran_WecB PF03808.13 KIK46126.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family NAD_binding_10 PF13460.6 KIK46126.1 - 0.19 11.6 0.4 0.3 11.0 0.4 1.3 1 0 0 1 1 1 0 NAD(P)H-binding ChaC PF04752.12 KIK46127.1 - 3.8e-45 154.1 0.0 4.6e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein PDR_assoc PF08370.11 KIK46128.1 - 0.27 11.0 2.1 0.44 10.3 0.1 2.3 2 1 1 3 3 3 0 Plant PDR ABC transporter associated TPR_10 PF13374.6 KIK46130.1 - 0.17 11.8 0.7 5.9 6.9 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Aminotran_4 PF01063.19 KIK46133.1 - 3.8e-26 92.3 0.0 4.5e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV tRNA_U5-meth_tr PF05958.11 KIK46134.1 - 2.2e-14 53.2 0.0 7.1e-13 48.3 0.0 2.3 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 KIK46134.1 - 5.2e-05 23.9 0.0 0.00014 22.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK46134.1 - 0.0013 18.5 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK46134.1 - 0.0036 17.9 0.0 0.0077 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 KIK46134.1 - 0.0064 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 KIK46134.1 - 0.029 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.15 KIK46134.1 - 0.049 13.3 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF21 PF01595.20 KIK46135.1 - 4.8e-34 117.6 0.1 7.4e-34 117.0 0.1 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KIK46135.1 - 0.0012 19.3 0.4 2.3 8.8 0.0 3.2 3 0 0 3 3 3 2 CBS domain Abhydrolase_1 PF00561.20 KIK46136.1 - 1.3e-44 152.8 0.0 4.3e-44 151.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KIK46136.1 - 0.094 12.8 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_6 PF12697.7 KIK46136.1 - 0.28 11.7 10.4 2.3 8.8 10.4 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family tRNA-synt_1c PF00749.21 KIK46137.1 - 7e-80 268.2 0.0 8.9e-80 267.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain zf-UBR PF02207.20 KIK46138.1 - 1e-16 60.9 16.5 1e-16 60.9 16.5 2.7 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KIK46138.1 - 5.7e-09 35.6 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Helicase_C PF00271.31 KIK46139.1 - 1.2e-14 54.6 0.0 2.1e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KIK46139.1 - 1.7e-11 43.4 0.0 2.6e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ERCC3_RAD25_C PF16203.5 KIK46139.1 - 0.0088 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KIK46139.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Herpes_gE PF02480.16 KIK46140.1 - 0.00026 19.9 0.1 0.00051 18.9 0.0 1.5 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E Mid2 PF04478.12 KIK46140.1 - 0.038 13.8 0.4 0.084 12.7 0.0 1.7 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor stn_TNFRSF12A PF12191.8 KIK46140.1 - 0.043 14.0 0.6 0.091 13.0 0.0 1.9 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Adeno_E3_CR2 PF02439.15 KIK46140.1 - 0.12 12.1 0.2 0.25 11.2 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SR-25 PF10500.9 KIK46141.1 - 4.6 6.8 10.7 8 6.0 10.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Bromodomain PF00439.25 KIK46143.1 - 2.6e-14 53.0 0.1 4.7e-14 52.2 0.1 1.3 1 0 0 1 1 1 1 Bromodomain Rubis-subs-bind PF09273.11 KIK46143.1 - 0.12 13.0 0.0 0.25 12.1 0.0 1.5 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding zf-C2H2 PF00096.26 KIK46145.1 - 5.3e-10 39.2 4.9 0.00027 21.2 1.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK46145.1 - 3.7e-07 30.3 7.3 2.1e-05 24.7 0.2 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK46145.1 - 0.00031 21.3 7.4 0.15 12.9 0.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KIK46145.1 - 0.0018 17.9 1.7 0.18 11.6 0.2 2.6 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KIK46145.1 - 0.031 14.2 4.2 0.062 13.2 1.1 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KIK46145.1 - 0.034 14.1 1.6 0.39 10.8 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KIK46145.1 - 0.099 12.4 1.4 0.39 10.5 0.0 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type GNAT_acetyltr_2 PF13718.6 KIK46145.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 zf-C2H2_jaz PF12171.8 KIK46145.1 - 1.7 9.1 6.4 4.1 7.8 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding NAM-associated PF14303.6 KIK46145.1 - 8.9 7.0 10.5 21 5.8 3.3 2.3 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain AAA_33 PF13671.6 KIK46146.1 - 3.7e-05 23.9 0.4 0.00032 20.9 0.4 2.1 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 KIK46146.1 - 0.00011 22.0 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KIK46146.1 - 0.00038 21.0 0.3 0.0079 16.7 0.3 2.2 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 KIK46146.1 - 0.028 13.4 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 KIK46146.1 - 0.04 13.2 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.10 KIK46146.1 - 0.063 12.7 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.6 KIK46146.1 - 0.13 12.7 0.1 0.2 12.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KIK46146.1 - 0.17 11.0 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.6 KIK46146.1 - 0.2 12.1 0.0 1.1 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain CM2 PF03021.14 KIK46147.1 - 0.065 13.1 0.0 0.065 13.1 0.0 1.1 1 0 0 1 1 1 0 Influenza C virus M2 protein DUF3833 PF12915.7 KIK46148.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3833) Sdh5 PF03937.16 KIK46153.1 - 3.4e-28 97.4 0.4 4.8e-28 96.9 0.4 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Gly_transf_sug PF04488.15 KIK46154.1 - 7.3e-09 36.2 0.0 1.2e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KIK46154.1 - 0.0025 17.2 0.2 0.0038 16.6 0.2 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Prot_inhib_II PF02428.15 KIK46155.1 - 0.092 13.2 0.1 0.12 12.8 0.1 1.2 1 0 0 1 1 1 0 Potato type II proteinase inhibitor family Pacs-1 PF10254.9 KIK46155.1 - 0.11 11.5 0.0 0.12 11.4 0.0 1.0 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Aminotran_5 PF00266.19 KIK46156.1 - 1.9e-37 129.1 0.0 2.8e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V MR_MLE_C PF13378.6 KIK46157.1 - 3.1e-55 187.1 0.1 4e-55 186.7 0.1 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KIK46157.1 - 2.3e-22 79.4 0.0 4.6e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Amidohydro_2 PF04909.14 KIK46157.1 - 0.014 15.2 0.5 0.021 14.6 0.2 1.6 2 0 0 2 2 2 0 Amidohydrolase EMP24_GP25L PF01105.24 KIK46158.1 - 1.2e-37 129.6 0.0 1.3e-37 129.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Trimer_CC PF08954.11 KIK46158.1 - 0.0061 16.1 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Trimerisation motif TRPM_tetra PF16519.5 KIK46158.1 - 0.017 15.2 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Tetramerisation domain of TRPM PhoR PF11808.8 KIK46158.1 - 0.35 11.3 3.3 6 7.4 0.3 2.7 3 0 0 3 3 3 0 Phosphate regulon sensor protein PhoR UPF0506 PF11703.8 KIK46160.1 - 0.0012 19.2 5.7 0.0018 18.6 5.7 1.4 1 0 0 1 1 1 1 UPF0506 Conotoxin_I2 PF17557.2 KIK46160.1 - 0.0083 16.2 13.5 0.013 15.6 13.5 1.3 1 0 0 1 1 1 1 I2-superfamily conotoxins MDH PF02315.16 KIK46160.1 - 0.058 13.5 0.2 0.068 13.2 0.2 1.1 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit Toxin_21 PF08091.11 KIK46160.1 - 0.17 11.8 14.9 0.3 11.0 14.6 1.7 1 1 0 1 1 1 0 Spider insecticidal peptide Ceramidase_alk PF04734.13 KIK46160.1 - 0.43 9.2 3.6 0.44 9.1 3.6 1.0 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, N-terminal Conotoxin PF02950.17 KIK46160.1 - 0.72 10.9 10.9 0.92 10.6 10.6 1.5 1 1 0 1 1 1 0 Conotoxin Methyltransf_2 PF00891.18 KIK46161.1 - 2.8e-24 85.6 0.0 4e-23 81.8 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KIK46161.1 - 3.3e-05 24.5 0.0 8.4e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK46161.1 - 0.00011 22.1 0.0 0.00025 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK46161.1 - 0.0003 21.4 0.0 0.00071 20.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK46161.1 - 0.00038 21.1 0.0 0.00088 20.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK46161.1 - 0.00043 19.9 0.0 0.00084 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain GidB PF02527.15 KIK46161.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_16 PF10294.9 KIK46161.1 - 0.091 12.5 0.0 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 Lysine methyltransferase HTH_IclR PF09339.10 KIK46161.1 - 0.11 12.3 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF938 PF06080.12 KIK46161.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) RPA_C PF08784.11 KIK46161.1 - 0.17 12.5 0.0 1.1 9.9 0.0 2.1 1 1 1 2 2 2 0 Replication protein A C terminal Dus PF01207.17 KIK46162.1 - 1.9e-50 171.8 0.0 2.4e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KIK46162.1 - 0.0018 17.8 0.0 0.0093 15.4 0.0 2.0 2 0 0 2 2 2 1 Histidine biosynthesis protein DUF805 PF05656.14 KIK46163.1 - 0.15 12.5 0.9 0.38 11.2 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF805) ADK_lid PF05191.14 KIK46165.1 - 0.013 15.5 0.0 0.015 15.3 0.0 1.3 1 1 0 1 1 1 0 Adenylate kinase, active site lid ADH_N PF08240.12 KIK46166.1 - 5.7e-28 97.0 0.2 9.8e-28 96.2 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK46166.1 - 7.8e-23 80.9 0.0 1.6e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIK46166.1 - 7.2e-11 42.0 0.0 7.1e-08 32.2 0.0 2.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KIK46166.1 - 7.8e-08 33.4 0.0 1.7e-07 32.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KIK46166.1 - 0.00044 19.6 0.1 0.0011 18.3 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KIK46166.1 - 0.00096 18.8 0.1 0.0017 18.0 0.1 1.4 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_11 PF08241.12 KIK46166.1 - 0.0027 18.3 0.0 0.0065 17.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK46166.1 - 0.0032 18.1 0.1 0.0079 16.9 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIK46166.1 - 0.0089 15.6 0.1 0.016 14.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KIK46166.1 - 0.017 14.5 0.1 0.027 13.9 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) 2-Hacid_dh_C PF02826.19 KIK46166.1 - 0.061 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 KIK46167.1 - 2.5e-56 190.9 0.0 2.9e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK46167.1 - 3.7e-51 173.4 0.0 4.9e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK46167.1 - 1.3e-15 57.8 0.0 1.8e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK46167.1 - 0.00038 20.0 0.0 0.00085 18.8 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KIK46167.1 - 0.0014 18.0 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KIK46167.1 - 0.0076 15.4 0.1 0.044 12.9 0.0 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain PALP PF00291.25 KIK46167.1 - 0.015 14.7 0.1 0.022 14.2 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Glyco_tran_WecB PF03808.13 KIK46167.1 - 0.017 15.0 0.0 5.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family GDP_Man_Dehyd PF16363.5 KIK46167.1 - 0.026 13.9 0.0 0.053 12.9 0.0 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 KIK46167.1 - 0.028 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.13 KIK46167.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Histone PF00125.24 KIK46171.1 - 2.8e-22 79.5 2.7 3.7e-22 79.1 2.7 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KIK46171.1 - 0.00025 21.3 0.2 0.00025 21.3 0.2 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KIK46171.1 - 0.00036 21.0 0.0 0.00065 20.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.24 KIK46172.1 - 3.4e-19 69.5 0.0 4.3e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KIK46172.1 - 9.9e-16 57.2 0.2 2.1e-15 56.1 0.2 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KIK46172.1 - 9.3e-08 32.2 0.0 1.3e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HECT_2 PF09814.9 KIK46173.1 - 3.7e-48 164.3 0.0 5.4e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Homeobox_KN PF05920.11 KIK46173.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain WD40 PF00400.32 KIK46174.1 - 3.2e-11 43.6 9.0 0.00075 20.3 0.0 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK46174.1 - 2.5e-06 27.7 0.5 0.77 10.1 0.0 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain GtrA PF04138.14 KIK46174.1 - 1.7 8.9 13.3 0.024 14.8 4.4 2.2 2 0 0 2 2 2 0 GtrA-like protein 2-oxoacid_dh PF00198.23 KIK46175.1 - 5.7e-83 277.9 0.3 9.1e-83 277.3 0.1 1.4 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KIK46175.1 - 6.4e-20 70.8 1.7 1.2e-19 69.9 1.7 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KIK46175.1 - 2e-06 27.5 0.3 9.8e-06 25.3 0.2 2.1 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KIK46175.1 - 0.00019 22.1 0.2 0.1 13.3 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.19 KIK46175.1 - 0.001 18.9 0.5 0.0026 17.7 0.5 1.7 1 0 0 1 1 1 1 Glycine cleavage H-protein eIF-3_zeta PF05091.12 KIK46175.1 - 0.23 10.4 1.9 3.3 6.6 0.3 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NAM-associated PF14303.6 KIK46175.1 - 1.7 9.4 9.2 2.9 8.6 9.2 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain GRAB PF10375.9 KIK46176.1 - 6e-05 22.7 2.9 0.00013 21.7 2.9 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Bap31_Bap29_C PF18035.1 KIK46176.1 - 0.0022 17.9 5.0 0.53 10.3 0.7 3.3 2 0 0 2 2 2 2 Bap31/Bap29 cytoplasmic coiled-coil domain GRIP PF01465.20 KIK46176.1 - 0.0065 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 GRIP domain Laminin_II PF06009.12 KIK46176.1 - 0.059 13.4 21.6 0.57 10.2 5.9 2.5 2 0 0 2 2 2 0 Laminin Domain II GldM_N PF12081.8 KIK46176.1 - 0.47 10.5 15.2 0.68 10.0 3.3 3.1 2 1 1 4 4 4 0 GldM N-terminal domain RasGAP_C PF03836.15 KIK46176.1 - 1.1 9.4 18.1 1.6 8.9 6.9 2.5 2 1 0 2 2 2 0 RasGAP C-terminus DUF1664 PF07889.12 KIK46176.1 - 5.8 7.0 15.0 2.8 8.0 1.9 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2937 PF11157.8 KIK46176.1 - 9.1 6.0 11.4 10 5.8 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2937) Gly_transf_sug PF04488.15 KIK46178.1 - 3.2e-08 34.1 0.0 5.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KIK46178.1 - 0.0048 16.3 0.1 0.0071 15.8 0.1 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Conotoxin PF02950.17 KIK46180.1 - 0.18 12.8 8.1 0.095 13.7 6.0 1.7 2 0 0 2 2 2 0 Conotoxin Conotoxin_I2 PF17557.2 KIK46180.1 - 0.37 10.9 9.5 1.1 9.4 9.5 1.9 1 1 0 1 1 1 0 I2-superfamily conotoxins PcF PF09461.10 KIK46181.1 - 0.0097 16.3 4.4 0.0097 16.3 4.4 1.6 2 0 0 2 2 2 1 Phytotoxin PcF protein Conotoxin_I2 PF17557.2 KIK46181.1 - 0.3 11.2 9.5 0.65 10.1 9.5 1.6 1 1 0 1 1 1 0 I2-superfamily conotoxins Toxin_12 PF07740.12 KIK46181.1 - 0.5 11.1 12.5 1.9 9.3 12.5 2.0 1 1 0 1 1 1 0 Ion channel inhibitory toxin LEAP-2 PF07359.11 KIK46181.1 - 0.94 9.4 5.5 0.86 9.5 4.5 1.6 1 1 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Toxin_27 PF08099.11 KIK46181.1 - 2.6 8.2 15.1 0.29 11.3 7.7 2.3 1 1 1 2 2 2 0 Scorpion calcine family PPTA PF01239.22 KIK46182.1 - 7.3e-46 152.7 13.5 3.5e-10 39.3 0.1 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat PSCyt2 PF07583.11 KIK46182.1 - 0.072 13.0 0.3 0.13 12.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) AbiJ_NTD4 PF18863.1 KIK46182.1 - 0.2 12.1 2.1 0.36 11.3 2.0 1.6 1 1 0 1 1 1 0 AbiJ N-terminal domain 4 RRM_1 PF00076.22 KIK46183.1 - 2.3e-13 49.8 0.0 3.3e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KIK46183.1 - 1.9e-07 31.5 0.5 1.9e-07 31.5 0.5 2.6 3 0 0 3 3 3 2 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 KIK46183.1 - 0.025 14.4 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF3446 PF11928.8 KIK46183.1 - 1.1 9.6 5.1 6.6 7.1 0.6 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain RNA_pol_3_Rpc31 PF11705.8 KIK46184.1 - 2e-26 93.6 4.6 3.4e-26 92.9 4.6 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Homoserine_dh PF00742.19 KIK46187.1 - 1.7e-48 164.8 0.0 2.6e-48 164.2 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KIK46187.1 - 6.2e-18 65.6 0.0 1.4e-17 64.4 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 KIK46187.1 - 0.0082 16.3 0.1 0.02 15.0 0.1 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 KIK46187.1 - 0.013 15.8 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Cys_Met_Meta_PP PF01053.20 KIK46187.1 - 0.062 11.8 0.2 3 6.3 0.0 2.4 2 1 0 3 3 3 0 Cys/Met metabolism PLP-dependent enzyme PHB_acc_N PF07879.11 KIK46187.1 - 0.21 11.7 0.5 0.8 9.8 0.0 2.2 3 0 0 3 3 3 0 PHB/PHA accumulation regulator DNA-binding domain PNRC PF15365.6 KIK46188.1 - 0.003 17.3 5.3 0.003 17.3 5.3 3.0 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator motif DUF3464 PF11947.8 KIK46188.1 - 0.23 11.2 2.6 0.46 10.2 2.6 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 PapA_C PF16911.5 KIK46188.1 - 0.78 9.8 3.7 5.9 7.0 0.1 2.5 2 0 0 2 2 2 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus TFIIF_alpha PF05793.12 KIK46188.1 - 6.9 5.1 6.1 1.2 7.7 2.0 1.7 1 1 1 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Glyco_transf_24 PF18404.1 KIK46189.1 - 1.1e-142 474.2 1.1 1.6e-142 473.7 1.1 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KIK46189.1 - 3.8e-49 167.9 0.0 5.9e-46 157.5 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KIK46189.1 - 3.2e-38 130.2 0.0 6.2e-38 129.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_15 PF18403.1 KIK46189.1 - 1.2e-36 126.7 0.1 1.5e-35 123.1 0.0 2.5 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KIK46189.1 - 1.2e-26 93.7 0.0 2.4e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 KIK46189.1 - 1.3e-23 83.5 0.0 5.6e-23 81.4 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KIK46189.1 - 3.1e-05 23.7 0.0 5.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 NARG2_C PF10505.9 KIK46190.1 - 0.015 14.8 0.2 0.025 14.1 0.1 1.3 1 1 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus HLH PF00010.26 KIK46190.1 - 0.032 14.2 0.2 0.12 12.4 0.3 1.8 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain Thaumatin PF00314.17 KIK46193.1 - 1.1e-74 250.7 10.2 1.3e-74 250.5 10.2 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KIK46193.1 - 0.00017 21.0 1.8 0.0074 15.6 0.0 2.1 2 0 0 2 2 2 2 Beta-1,3-glucanase HLH PF00010.26 KIK46194.1 - 8.1e-07 28.9 0.8 1.4e-06 28.2 0.8 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain UPF0242 PF06785.11 KIK46196.1 - 0.017 15.2 1.2 0.022 14.9 1.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Tsi6 PF18660.1 KIK46196.1 - 0.023 14.7 0.1 0.037 14.1 0.1 1.2 1 0 0 1 1 1 0 Tsi6 DHR10 PF18595.1 KIK46196.1 - 0.034 14.2 3.3 0.034 14.2 3.3 1.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain VPS11_C PF12451.8 KIK46196.1 - 0.053 13.8 1.2 2 8.7 0.0 2.4 1 1 1 2 2 2 0 Vacuolar protein sorting protein 11 C terminal DUF5101 PF17031.5 KIK46196.1 - 0.065 13.3 0.1 0.11 12.6 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5101) PCSK9_C2 PF18464.1 KIK46197.1 - 0.015 15.3 0.1 0.017 15.1 0.1 1.1 1 0 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain RabGAP-TBC PF00566.18 KIK46200.1 - 6.1e-20 71.8 0.0 8.8e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Vps39_2 PF10367.9 KIK46201.1 - 3.2e-08 34.0 0.0 9e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KIK46201.1 - 0.0065 16.7 0.0 0.055 13.8 0.0 2.6 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Phytochelatin_C PF09328.10 KIK46201.1 - 0.083 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) DUF2401 PF10287.9 KIK46202.1 - 0.17 11.4 0.0 0.19 11.3 0.0 1.0 1 0 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) MFS_1 PF07690.16 KIK46203.1 - 1.9e-30 106.0 31.4 2.3e-30 105.7 29.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily SH PF01445.17 KIK46203.1 - 0.31 11.1 4.2 0.43 10.6 0.2 2.9 1 1 1 2 2 2 0 Viral small hydrophobic protein MFS_1 PF07690.16 KIK46204.1 - 5.2e-30 104.6 31.1 5.2e-30 104.6 31.1 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KIK46205.1 - 2.8e-27 95.6 34.3 2.8e-27 95.6 34.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Perilipin PF03036.16 KIK46206.1 - 2e-09 37.0 13.0 3.8e-07 29.5 0.2 3.5 1 1 0 2 2 2 2 Perilipin family Apolipoprotein PF01442.18 KIK46206.1 - 3e-05 24.0 1.1 0.00021 21.2 0.1 2.4 2 1 1 3 3 3 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 KIK46206.1 - 0.0057 16.8 8.9 0.24 11.5 7.4 3.4 3 1 0 3 3 3 1 Apolipophorin-III precursor (apoLp-III) CdvA PF18822.1 KIK46206.1 - 0.0071 16.2 1.7 3.8 7.4 0.1 3.2 3 1 1 4 4 4 2 CdvA-like coiled-coil domain 4HB PF17947.1 KIK46206.1 - 0.0081 16.2 0.1 0.83 9.8 0.0 2.7 2 0 0 2 2 2 1 Four helical bundle domain Adenylate_cycl PF01295.18 KIK46206.1 - 0.016 13.8 2.0 0.023 13.3 2.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase, class-I TBK1_CCD1 PF18394.1 KIK46206.1 - 0.024 14.2 1.5 0.039 13.5 1.5 1.3 1 0 0 1 1 1 0 TANK-binding kinase 1 coiled-coil domain 1 eIF-5a PF01287.20 KIK46206.1 - 0.08 13.1 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Syntaxin-6_N PF09177.11 KIK46206.1 - 0.084 13.4 0.6 0.26 11.9 0.5 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal YtxH PF12732.7 KIK46206.1 - 0.1 13.1 1.3 7.8 7.1 0.0 3.4 3 1 0 3 3 3 0 YtxH-like protein EF-G-binding_N PF07299.11 KIK46206.1 - 0.29 11.7 2.9 3.2 8.3 1.0 2.6 1 1 1 2 2 2 0 Elongation factor G-binding protein, N-terminal Prominin PF05478.11 KIK46206.1 - 1.3 6.8 6.6 0.8 7.6 5.0 1.4 2 0 0 2 2 2 0 Prominin AIP3 PF03915.13 KIK46206.1 - 1.5 7.8 7.5 1.3 8.0 5.7 1.7 1 1 0 1 1 1 0 Actin interacting protein 3 Seryl_tRNA_N PF02403.22 KIK46206.1 - 2.2 8.6 5.5 0.44 10.8 1.2 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 KIK46206.1 - 4.3 7.5 7.6 9.8 6.4 1.0 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Cys_Met_Meta_PP PF01053.20 KIK46207.1 - 6.9e-25 87.4 0.0 1e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme F5_F8_type_C PF00754.25 KIK46208.1 - 0.0005 20.2 0.1 0.00067 19.8 0.1 1.2 1 0 0 1 1 1 1 F5/8 type C domain Laminin_N PF00055.17 KIK46208.1 - 0.06 12.9 0.1 0.076 12.6 0.1 1.2 1 0 0 1 1 1 0 Laminin N-terminal (Domain VI) TcpS PF17456.2 KIK46209.1 - 0.18 11.8 0.0 0.18 11.8 0.0 1.0 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S CBS PF00571.28 KIK46211.1 - 2.4e-14 53.5 0.0 0.00036 20.9 0.0 4.4 5 1 0 5 5 5 3 CBS domain Abhydrolase_6 PF12697.7 KIK46212.1 - 2.3e-13 51.3 0.0 2.9e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK46212.1 - 1e-09 38.4 0.0 1.8e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK46212.1 - 1.2e-07 31.3 0.0 1.7e-07 30.8 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KIK46212.1 - 0.00023 20.2 0.0 0.0013 17.7 0.0 2.1 2 1 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KIK46212.1 - 0.0086 15.1 0.0 0.036 13.1 0.0 1.9 1 1 0 1 1 1 1 Chlorophyllase Abhydrolase_6 PF12697.7 KIK46213.1 - 9.1e-13 49.3 0.2 1.2e-12 49.0 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK46213.1 - 8.1e-11 42.0 0.0 1.2e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK46213.1 - 6.2e-09 35.5 0.0 9.2e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KIK46213.1 - 7.9e-05 21.7 0.0 0.0002 20.4 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KIK46213.1 - 0.0018 17.4 0.0 0.0094 15.0 0.0 1.9 1 1 0 1 1 1 1 Chlorophyllase PGAP1 PF07819.13 KIK46213.1 - 0.048 13.4 0.0 0.66 9.7 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein Abhydro_lipase PF04083.16 KIK46213.1 - 0.096 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region BDV_G PF06208.11 KIK46214.1 - 0.051 12.7 0.4 0.062 12.4 0.4 1.1 1 0 0 1 1 1 0 Borna disease virus G protein WW PF00397.26 KIK46215.1 - 0.78 9.9 6.0 0.22 11.6 0.9 2.2 2 0 0 2 2 2 0 WW domain Slx4 PF09494.10 KIK46216.1 - 0.045 13.7 0.1 0.084 12.8 0.1 1.5 1 0 0 1 1 1 0 Slx4 endonuclease DUF2189 PF09955.9 KIK46216.1 - 0.096 12.9 4.0 0.15 12.3 4.0 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) Phosphodiest PF01663.22 KIK46217.1 - 2.9e-08 33.7 0.7 2.9e-08 33.7 0.7 1.9 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KIK46217.1 - 0.052 12.9 0.1 0.22 10.9 0.0 1.9 2 0 0 2 2 2 0 Sulfatase Peptidase_U4 PF03419.13 KIK46217.1 - 0.16 11.2 10.9 2.9 7.1 5.9 2.8 1 1 1 2 2 2 0 Sporulation factor SpoIIGA F-box PF00646.33 KIK46218.1 - 2.2e-06 27.4 0.1 6.2e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK46218.1 - 2.6e-05 24.0 0.4 8.9e-05 22.3 0.4 2.0 1 0 0 1 1 1 1 F-box-like CNH PF00780.22 KIK46219.1 - 1.2e-15 57.9 0.0 1.5e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 CNH domain DUF1611 PF07755.11 KIK46219.1 - 0.033 13.5 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain VirC2 PF07181.11 KIK46221.1 - 0.0087 15.6 0.3 0.012 15.0 0.3 1.1 1 0 0 1 1 1 1 VirC2 protein eIF_4EBP PF05456.11 KIK46221.1 - 0.026 14.5 0.1 0.031 14.2 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF755 PF05501.11 KIK46221.1 - 3.4 8.0 17.1 0.66 10.3 7.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) IMUP PF15761.5 KIK46221.1 - 7 7.4 13.4 1.9 9.2 3.6 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein Oxidored_FMN PF00724.20 KIK46222.1 - 1.3e-05 24.7 1.5 0.0011 18.3 0.0 2.7 3 1 0 3 3 3 2 NADH:flavin oxidoreductase / NADH oxidase family Zn_clus PF00172.18 KIK46226.1 - 0.0012 18.9 12.9 0.0018 18.4 12.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MAM33 PF02330.16 KIK46228.1 - 6e-69 232.2 2.3 7.1e-69 232.0 2.3 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Aldedh PF00171.22 KIK46230.1 - 1.2e-77 261.4 0.0 1.5e-77 261.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Exo_endo_phos PF03372.23 KIK46232.1 - 1.7e-17 63.8 0.0 2.3e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 2TM PF13239.6 KIK46232.1 - 0.099 13.0 1.4 0.2 12.0 1.4 1.6 1 0 0 1 1 1 0 2TM domain Abhydrolase_3 PF07859.13 KIK46233.1 - 7.3e-43 146.9 0.1 1.3e-42 146.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK46233.1 - 4.8e-14 52.0 0.0 5.3e-13 48.6 0.0 2.0 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 KIK46233.1 - 0.076 11.9 0.0 0.25 10.2 0.0 1.7 2 0 0 2 2 2 0 Carboxylesterase family L51_S25_CI-B8 PF05047.16 KIK46233.1 - 0.084 12.8 0.0 0.27 11.2 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Abhydrolase_6 PF12697.7 KIK46233.1 - 0.75 10.4 4.7 0.2 12.3 1.6 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_M24 PF00557.24 KIK46234.1 - 1.1e-42 146.1 0.0 1.5e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 YL1 PF05764.13 KIK46234.1 - 0.31 11.1 11.6 0.44 10.6 11.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein RNA_polI_A34 PF08208.11 KIK46234.1 - 0.73 9.9 12.1 1.4 9.0 12.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CENP-T_C PF15511.6 KIK46235.1 - 3.4e-07 30.4 0.0 4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIK46235.1 - 4.9e-05 23.4 0.1 7.1e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIK46235.1 - 0.00011 22.5 0.0 0.00014 22.2 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIK46235.1 - 0.00075 19.7 0.1 0.0015 18.8 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK46235.1 - 0.0016 18.8 0.2 0.0017 18.7 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIK46235.1 - 0.049 13.7 0.0 0.055 13.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit RibD_C PF01872.17 KIK46236.1 - 6.6e-33 114.2 0.0 8.2e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain RhoGEF PF00621.20 KIK46237.1 - 2.1e-10 41.2 0.0 2.7e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain Myb_Cef PF11831.8 KIK46238.1 - 0.014 14.9 1.6 0.22 11.0 1.0 2.4 2 0 0 2 2 2 0 pre-mRNA splicing factor component X PF00739.19 KIK46238.1 - 2.9 8.0 5.5 0.7 10.0 0.8 2.5 2 0 0 2 2 2 0 Trans-activation protein X N_BRCA1_IG PF16158.5 KIK46240.1 - 1.4e-28 99.6 0.1 3.6e-28 98.3 0.1 1.8 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KIK46240.1 - 9.5e-26 89.4 49.9 1.4e-10 40.8 3.5 4.5 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 KIK46240.1 - 0.0024 18.1 46.1 0.0049 17.2 4.3 4.6 4 0 0 4 4 4 4 C1 domain DHBP_synthase PF00926.19 KIK46241.1 - 4.9e-57 192.6 0.0 5.5e-57 192.4 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Mito_carr PF00153.27 KIK46243.1 - 1.7e-29 101.6 8.4 7.8e-17 61.0 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Aminotran_4 PF01063.19 KIK46244.1 - 2.2e-21 76.7 0.0 2.8e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV WD40 PF00400.32 KIK46245.1 - 6.9e-57 188.1 25.5 1.9e-06 28.5 0.1 12.1 12 0 0 12 12 12 9 WD domain, G-beta repeat Utp13 PF08625.11 KIK46245.1 - 7.3e-47 158.8 0.0 1.2e-46 158.2 0.0 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KIK46245.1 - 2.3e-12 47.0 1.3 0.44 10.9 0.0 7.9 5 3 5 10 10 10 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK46245.1 - 1.5e-06 27.4 1.1 0.81 8.6 0.0 4.9 3 1 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK46245.1 - 2.2e-06 27.2 0.0 7.5e-05 22.2 0.0 2.9 3 0 0 3 3 3 1 WD40-like domain Nup160 PF11715.8 KIK46245.1 - 0.00018 20.3 2.9 3.5 6.1 0.0 4.4 3 1 0 3 3 3 2 Nucleoporin Nup120/160 Arena_nucleocap PF00843.17 KIK46245.1 - 0.0097 14.8 0.1 0.91 8.4 0.0 2.7 2 0 0 2 2 2 1 Arenavirus nucleocapsid N-terminal domain Mcl1_mid PF12341.8 KIK46245.1 - 0.021 14.2 0.5 0.27 10.5 0.0 2.8 3 1 1 4 4 4 0 Minichromosome loss protein, Mcl1, middle region Frtz PF11768.8 KIK46245.1 - 0.045 12.1 0.1 3.2 6.0 0.0 2.3 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Forkhead PF00250.18 KIK46246.1 - 1.1e-18 67.3 0.0 1.9e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain AT_hook PF02178.19 KIK46246.1 - 3.2e-05 23.3 7.7 0.011 15.5 0.5 2.8 2 0 0 2 2 2 2 AT hook motif Fib_alpha PF08702.10 KIK46246.1 - 0.18 12.0 0.7 0.32 11.2 0.7 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Macoilin PF09726.9 KIK46246.1 - 0.9 8.0 4.7 1.3 7.5 4.7 1.2 1 0 0 1 1 1 0 Macoilin family Fungal_trans PF04082.18 KIK46247.1 - 1.4e-37 129.2 0.0 2.2e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK46247.1 - 0.011 15.8 7.5 0.021 14.9 7.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NIPSNAP PF07978.13 KIK46248.1 - 8.3e-33 112.7 2.4 3.1e-26 91.6 0.3 2.1 2 0 0 2 2 2 2 NIPSNAP Glycos_transf_2 PF00535.26 KIK46249.1 - 0.025 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIK46249.1 - 0.046 13.6 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Proteasome PF00227.26 KIK46250.1 - 4e-37 127.5 0.0 4.6e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Trans_coact PF16805.5 KIK46250.1 - 0.18 11.9 0.2 1.7 8.8 0.1 2.3 3 0 0 3 3 3 0 Phage late-transcription coactivator Mito_carr PF00153.27 KIK46251.1 - 6.3e-21 74.1 0.5 1.9e-07 30.9 0.0 4.9 4 1 0 4 4 4 4 Mitochondrial carrier protein TMEM171 PF15471.6 KIK46251.1 - 8.1 5.3 7.1 13 4.6 7.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Wtap PF17098.5 KIK46252.1 - 0.00035 20.5 0.8 0.00069 19.6 0.8 1.4 1 0 0 1 1 1 1 WTAP/Mum2p family ZapB PF06005.12 KIK46252.1 - 0.014 15.8 3.1 0.026 15.0 3.1 1.4 1 0 0 1 1 1 0 Cell division protein ZapB T3SSipB PF16535.5 KIK46252.1 - 0.015 15.8 2.0 0.023 15.2 2.0 1.2 1 0 0 1 1 1 0 Type III cell invasion protein SipB NRBF2 PF08961.10 KIK46252.1 - 0.028 14.0 0.5 0.048 13.3 0.5 1.3 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator DUF3086 PF11285.8 KIK46252.1 - 0.11 11.6 0.5 0.16 11.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) DivIC PF04977.15 KIK46252.1 - 0.2 11.4 1.6 0.47 10.2 1.6 1.5 1 0 0 1 1 1 0 Septum formation initiator YabA PF06156.13 KIK46252.1 - 0.35 11.5 1.4 0.68 10.6 1.4 1.4 1 0 0 1 1 1 0 Initiation control protein YabA YscJ_FliF PF01514.17 KIK46253.1 - 0.068 12.8 2.0 0.11 12.1 2.0 1.2 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family APG6_N PF17675.1 KIK46253.1 - 0.11 13.0 5.4 0.18 12.3 5.4 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Spc7 PF08317.11 KIK46253.1 - 1.6 7.5 7.1 2.3 7.0 7.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Peptidase_C48 PF02902.19 KIK46254.1 - 1.6e-39 136.0 0.4 2.6e-39 135.3 0.4 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Use1 PF09753.9 KIK46255.1 - 0.0081 15.9 0.1 0.01 15.6 0.1 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Sec20 PF03908.13 KIK46255.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 1 0 1 1 1 0 Sec20 SNARE PF05739.19 KIK46255.1 - 0.41 10.7 1.7 0.78 9.8 1.7 1.4 1 0 0 1 1 1 0 SNARE domain HupE_UreJ_2 PF13795.6 KIK46256.1 - 1.4 8.5 10.4 0.21 11.2 1.9 2.3 2 0 0 2 2 2 0 HupE / UreJ protein DUF1413 PF07205.11 KIK46258.1 - 0.14 12.1 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) MFS_1 PF07690.16 KIK46259.1 - 1.6e-10 40.4 36.2 2.2e-10 40.0 21.3 3.3 1 1 2 3 3 3 3 Major Facilitator Superfamily HNH_2 PF13391.6 KIK46259.1 - 0.14 12.3 0.1 0.26 11.5 0.1 1.5 1 0 0 1 1 1 0 HNH endonuclease ADH_N PF08240.12 KIK46260.1 - 2e-31 108.1 0.6 3.3e-31 107.4 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK46260.1 - 2.1e-22 79.5 0.1 3e-22 79.0 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIK46260.1 - 6.3e-06 25.8 0.1 7.5e-05 22.3 0.1 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KIK46260.1 - 6.2e-05 24.1 0.0 0.00036 21.6 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KIK46260.1 - 0.0094 16.6 0.0 0.019 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AlaDh_PNT_C PF01262.21 KIK46260.1 - 0.014 14.7 0.1 0.026 13.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KIK46260.1 - 0.086 12.2 0.0 0.2 11.0 0.0 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.6 KIK46260.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KIK46260.1 - 0.12 11.7 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Sgf11 PF08209.11 KIK46261.1 - 5.1e-13 48.3 0.8 1e-12 47.4 0.8 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) CAP_N PF01213.19 KIK46261.1 - 3.4 7.1 7.5 7.7 5.9 7.5 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Glyco_hydro_92 PF07971.12 KIK46263.1 - 7.8e-120 400.9 0.1 1e-119 400.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KIK46263.1 - 2.6e-57 194.5 1.2 3.9e-57 193.9 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain CBS PF00571.28 KIK46264.1 - 8.8e-36 122.2 7.0 2.1e-09 37.7 0.0 5.3 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 KIK46264.1 - 1.5e-09 37.6 0.0 4.4e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 PB1 domain Alpha_GJ PF03229.13 KIK46264.1 - 0.26 11.9 0.1 0.26 11.9 0.1 3.3 3 0 0 3 3 3 0 Alphavirus glycoprotein J Bac_export_2 PF01312.19 KIK46265.1 - 0.071 12.3 2.1 0.082 12.1 2.1 1.0 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Yip1 PF04893.17 KIK46265.1 - 0.73 9.5 10.6 2 8.1 10.0 1.7 1 1 1 2 2 2 0 Yip1 domain UPF0121 PF03661.13 KIK46266.1 - 3.6e-41 141.2 3.2 4e-41 141.0 3.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DEAD PF00270.29 KIK46267.1 - 8.6e-47 159.2 0.0 1.5e-46 158.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK46267.1 - 4.1e-25 88.3 0.0 6.6e-24 84.4 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KIK46267.1 - 1.1e-18 67.1 0.5 2.8e-18 65.9 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KIK46267.1 - 0.00018 21.5 0.0 0.00042 20.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIK46267.1 - 0.099 12.9 1.0 0.46 10.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain PTH2 PF01981.16 KIK46268.1 - 5.2e-41 139.6 0.1 6.7e-41 139.3 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Ribosomal_60s PF00428.19 KIK46268.1 - 0.07 13.7 1.6 0.13 12.8 1.6 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF2573 PF10835.8 KIK46268.1 - 0.14 12.5 0.0 0.21 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) Mpv17_PMP22 PF04117.12 KIK46270.1 - 1.4e-20 73.3 0.3 2.3e-20 72.6 0.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family WD40 PF00400.32 KIK46271.1 - 1.7e-09 38.2 22.8 0.13 13.1 0.0 8.4 8 1 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK46271.1 - 3.1e-06 27.4 0.0 0.012 15.9 0.0 5.1 7 0 0 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain BAT PF15915.5 KIK46271.1 - 0.0056 16.6 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 GAF and HTH_10 associated domain PD40 PF07676.12 KIK46271.1 - 0.023 14.6 2.0 16 5.6 0.0 3.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat zf-Tim10_DDP PF02953.15 KIK46272.1 - 2.8e-20 71.7 0.6 3.3e-20 71.5 0.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger zf-met2 PF12907.7 KIK46273.1 - 1.7e-16 60.0 3.5 2.7e-16 59.4 3.5 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 KIK46273.1 - 0.0094 16.8 6.0 0.0094 16.8 6.0 1.8 2 0 0 2 2 2 1 4F5 protein family zf-C2H2_12 PF18658.1 KIK46273.1 - 0.081 12.5 0.3 0.11 12.0 0.3 1.2 1 0 0 1 1 1 0 Zinc-finger C2H2-type Beta_elim_lyase PF01212.21 KIK46274.1 - 1.7e-69 234.3 0.0 2.2e-69 234.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KIK46274.1 - 8.3e-05 21.3 0.1 0.00014 20.6 0.1 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KIK46274.1 - 0.00046 19.5 0.0 0.00087 18.6 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KIK46274.1 - 0.0018 17.3 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KIK46274.1 - 0.019 14.3 0.0 0.038 13.3 0.0 1.5 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family 2H-phosphodiest PF08975.10 KIK46274.1 - 0.13 12.3 0.1 18 5.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1868) Beta_elim_lyase PF01212.21 KIK46275.1 - 2.9e-65 220.4 0.0 4e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Urb2 PF10441.9 KIK46276.1 - 4.8e-40 137.7 4.4 6.2e-39 134.1 0.0 3.1 3 0 0 3 3 3 2 Urb2/Npa2 family G-patch PF01585.23 KIK46277.1 - 7.3e-08 32.2 0.0 2.1e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 KIK46277.1 - 3.4e-05 24.0 6.5 5.2e-05 23.4 6.5 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIK46277.1 - 0.00026 21.3 2.4 0.00045 20.5 2.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type G-patch_2 PF12656.7 KIK46277.1 - 0.001 19.1 0.8 0.0027 17.7 0.0 2.1 2 0 0 2 2 2 1 G-patch domain zf-C2H2_2 PF12756.7 KIK46277.1 - 0.0068 16.7 0.8 0.011 16.1 0.8 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_aberr PF17017.5 KIK46277.1 - 0.015 15.5 0.6 0.022 14.9 0.6 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger DUF4820 PF16091.5 KIK46277.1 - 0.069 12.5 9.6 0.1 12.0 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) zf-DBF PF07535.12 KIK46277.1 - 0.63 10.2 3.0 1.1 9.4 3.0 1.4 1 0 0 1 1 1 0 DBF zinc finger SAE2 PF08573.10 KIK46277.1 - 1 10.5 8.4 42 5.3 0.0 2.3 1 1 1 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus CHAT PF12770.7 KIK46278.1 - 1.3e-41 142.9 0.0 3.2e-41 141.6 0.0 1.6 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK46278.1 - 4.8e-38 128.0 43.5 5.2e-05 23.0 0.3 12.7 13 0 0 13 13 13 10 Tetratricopeptide repeat TPR_12 PF13424.6 KIK46278.1 - 3.1e-14 53.0 40.3 0.55 10.5 2.2 13.6 7 3 6 13 13 12 8 Tetratricopeptide repeat GATase_4 PF13230.6 KIK46278.1 - 2.8e-11 42.8 0.7 0.58 9.0 0.0 7.1 2 1 7 9 9 9 6 Glutamine amidotransferases class-II TPR_7 PF13176.6 KIK46278.1 - 2e-05 24.3 13.5 19 5.5 0.0 8.3 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK46278.1 - 0.001 19.7 42.9 31 5.7 0.1 13.5 12 2 2 14 14 14 0 Tetratricopeptide repeat DUF1045 PF06299.12 KIK46278.1 - 0.0035 17.3 10.6 0.84 9.6 0.1 6.7 1 1 6 8 8 8 1 Protein of unknown function (DUF1045) TPR_1 PF00515.28 KIK46278.1 - 0.011 15.5 23.6 11 6.0 0.0 9.5 11 0 0 11 11 11 0 Tetratricopeptide repeat DUF4471 PF14740.6 KIK46278.1 - 0.092 12.0 0.0 54 2.9 0.0 5.2 8 0 0 8 8 8 0 Domain of unknown function (DUF4471) TPR_11 PF13414.6 KIK46278.1 - 0.19 11.5 17.1 14 5.5 0.0 8.7 10 0 0 10 10 10 0 TPR repeat HTH_27 PF13463.6 KIK46278.1 - 0.26 11.8 2.2 6.1e+02 1.0 0.0 6.2 8 0 0 8 8 8 0 Winged helix DNA-binding domain TPR_2 PF07719.17 KIK46278.1 - 0.41 10.9 30.7 74 3.8 0.1 11.8 13 0 0 13 13 13 0 Tetratricopeptide repeat DUF3246 PF11596.8 KIK46278.1 - 0.59 9.5 4.1 1 8.7 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Bromodomain PF00439.25 KIK46280.1 - 1.3e-39 134.1 0.0 1.1e-19 70.3 0.0 2.7 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KIK46280.1 - 3e-19 69.0 0.7 7.4e-19 67.7 0.7 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Hid1 PF12722.7 KIK46280.1 - 0.06 11.5 5.2 0.11 10.6 5.2 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FlxA PF14282.6 KIK46280.1 - 0.25 11.4 7.8 0.049 13.6 3.3 2.2 2 0 0 2 2 2 0 FlxA-like protein Rtf2 PF04641.12 KIK46280.1 - 5.1 6.4 15.2 12 5.1 15.2 1.6 1 0 0 1 1 1 0 Rtf2 RING-finger WD40 PF00400.32 KIK46281.1 - 1.6e-15 57.2 10.2 0.0004 21.1 0.1 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KIK46281.1 - 0.00015 20.8 0.2 0.0011 17.9 0.0 2.3 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KIK46281.1 - 0.00047 20.4 0.2 2.6 8.4 0.0 4.4 2 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK46281.1 - 0.044 13.7 0.2 11 5.9 0.0 3.5 2 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KIK46281.1 - 0.067 11.7 0.0 0.14 10.7 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain SAP18 PF06487.12 KIK46282.1 - 0.11 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) Frataxin_Cyay PF01491.16 KIK46283.1 - 2e-37 127.5 0.0 2.6e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Rhodanese PF00581.20 KIK46284.1 - 3.1e-14 53.4 0.0 5.4e-14 52.6 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain Ctr PF04145.15 KIK46286.1 - 4.7e-30 105.2 0.0 5.6e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Spt5-NGN PF03439.13 KIK46288.1 - 5.9e-22 77.4 0.0 1.2e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KIK46288.1 - 1e-17 64.9 7.7 1e-17 64.9 7.7 3.2 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 KIK46288.1 - 2.2e-17 62.4 22.5 0.00013 21.8 0.0 6.5 7 0 0 7 7 7 4 KOW motif CTD PF12815.7 KIK46288.1 - 8.5e-13 48.7 47.0 5.1e-09 36.6 17.0 3.3 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 NAM-associated PF14303.6 KIK46288.1 - 0.32 11.7 6.0 0.58 10.9 6.0 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SDA1 PF05285.12 KIK46288.1 - 1.8 7.9 21.2 2.9 7.2 21.2 1.2 1 0 0 1 1 1 0 SDA1 HAS-barrel PF09378.10 KIK46288.1 - 9.1 6.5 7.2 2 8.6 0.4 3.4 4 1 1 5 5 5 0 HAS barrel domain GRAB PF10375.9 KIK46289.1 - 0.08 12.8 0.4 0.19 11.6 0.4 1.7 1 0 0 1 1 1 0 GRIP-related Arf-binding domain Toxin_8 PF07365.12 KIK46290.1 - 0.035 14.3 0.5 0.048 13.8 0.4 1.4 1 1 0 1 1 1 0 Alpha conotoxin precursor Rhodanese PF00581.20 KIK46293.1 - 1.3e-17 64.2 0.0 5.3e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain V-ATPase_C PF03223.15 KIK46294.1 - 1.3e-127 426.2 0.6 1.5e-127 426.0 0.6 1.0 1 0 0 1 1 1 1 V-ATPase subunit C KH_1 PF00013.29 KIK46295.1 - 1.3e-39 133.8 0.8 5.6e-10 38.9 0.0 7.2 7 0 0 7 7 7 5 KH domain Phage_TAC_1 PF06222.11 KIK46295.1 - 0.055 13.2 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone Homoserine_dh PF00742.19 KIK46295.1 - 0.15 11.9 0.0 5.8 6.8 0.0 2.5 2 1 0 2 2 2 0 Homoserine dehydrogenase RWD PF05773.22 KIK46296.1 - 6.3e-12 45.8 0.0 1.1e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain IBR PF01485.21 KIK46296.1 - 1.6e-11 44.2 2.3 1.6e-11 44.2 2.3 4.0 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KIK46296.1 - 0.00046 20.4 12.0 0.00046 20.4 12.0 4.1 4 2 1 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 KIK46296.1 - 0.00057 19.8 8.3 0.00057 19.8 8.3 3.6 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIK46296.1 - 0.0047 16.9 9.5 0.0047 16.9 9.5 3.1 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIK46296.1 - 0.019 14.8 9.5 0.019 14.8 9.5 4.2 5 0 0 5 5 5 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KIK46296.1 - 8.9 6.0 27.6 1.1 8.9 7.6 4.6 4 0 0 4 4 4 0 Zinc-ribbon, C4HC2 type Toxin_12 PF07740.12 KIK46301.1 - 0.058 14.1 5.2 0.058 14.1 5.2 2.3 2 1 0 2 2 2 0 Ion channel inhibitory toxin Pkinase PF00069.25 KIK46302.1 - 7.9e-07 28.7 0.1 9.3e-07 28.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pox_ser-thr_kin PF05445.11 KIK46302.1 - 0.06 12.3 0.1 0.068 12.1 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AAA_6 PF12774.7 KIK46304.1 - 2.9e-125 417.6 0.0 2.9e-124 414.3 0.0 2.8 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KIK46304.1 - 7.8e-115 384.2 6.0 7.8e-115 384.2 6.0 3.1 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KIK46304.1 - 3.4e-73 245.4 0.3 3.4e-73 245.4 0.3 4.2 5 1 0 5 5 5 1 ATP-binding dynein motor region AAA_8 PF12780.7 KIK46304.1 - 2.7e-67 226.8 0.0 7.4e-67 225.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KIK46304.1 - 5.4e-53 180.2 0.0 1.5e-52 178.7 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 KIK46304.1 - 1.5e-44 151.7 0.0 1.5e-37 128.8 0.0 4.7 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 KIK46304.1 - 6.5e-39 133.9 5.0 1.1e-38 133.2 5.0 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 KIK46304.1 - 1e-36 126.2 0.0 2e-36 125.3 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KIK46304.1 - 4.7e-28 97.7 0.0 2.7e-26 92.0 0.0 3.7 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KIK46304.1 - 9.9e-27 93.6 0.0 1.9e-12 47.4 0.0 5.6 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KIK46304.1 - 4.1e-17 62.5 0.7 1.2e-15 57.8 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 KIK46304.1 - 1e-13 51.7 0.2 0.0062 16.8 0.0 5.8 5 0 0 5 5 4 2 AAA domain AAA PF00004.29 KIK46304.1 - 4.6e-13 49.7 0.1 0.018 15.4 0.0 5.1 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KIK46304.1 - 2.6e-12 47.1 0.1 0.12 12.5 0.0 6.2 6 0 0 6 6 5 3 AAA domain AAA_16 PF13191.6 KIK46304.1 - 1.9e-08 34.9 0.3 0.58 10.5 0.0 6.2 6 0 0 6 6 5 1 AAA ATPase domain AAA_18 PF13238.6 KIK46304.1 - 3.4e-08 34.1 0.8 0.15 12.6 0.0 6.0 5 0 0 5 5 5 2 AAA domain T2SSE PF00437.20 KIK46304.1 - 4.2e-06 26.0 0.0 0.0082 15.2 0.0 3.6 3 0 0 3 3 3 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 KIK46304.1 - 5.3e-06 26.0 0.3 0.65 9.3 0.0 3.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KIK46304.1 - 9.9e-05 22.7 2.7 0.31 11.4 0.0 4.9 5 0 0 5 5 4 1 AAA domain FtsK_SpoIIIE PF01580.18 KIK46304.1 - 0.00015 21.2 0.0 0.31 10.4 0.0 3.5 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_30 PF13604.6 KIK46304.1 - 0.00015 21.5 0.7 12 5.5 0.0 4.6 4 0 0 4 4 4 0 AAA domain IstB_IS21 PF01695.17 KIK46304.1 - 0.0003 20.6 0.4 0.78 9.4 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_lid_1 PF17857.1 KIK46304.1 - 0.00052 20.2 2.9 0.00082 19.5 0.0 2.9 3 0 0 3 3 2 1 AAA+ lid domain AAA_29 PF13555.6 KIK46304.1 - 0.0012 18.6 0.0 0.74 9.6 0.0 3.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 KIK46304.1 - 0.0029 18.0 0.2 15 6.1 0.0 4.7 5 0 0 5 5 4 0 RNA helicase AAA_21 PF13304.6 KIK46304.1 - 0.0033 17.3 0.1 3.6 7.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 KIK46304.1 - 0.0036 17.1 0.6 22 4.7 0.0 4.6 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 KIK46304.1 - 0.0067 17.0 1.8 9.5 6.7 0.0 4.5 4 0 0 4 4 3 0 ABC transporter LOH1CR12 PF10158.9 KIK46304.1 - 0.0079 16.2 10.9 0.098 12.7 0.3 4.1 3 0 0 3 3 2 1 Tumour suppressor protein Rad17 PF03215.15 KIK46304.1 - 0.02 14.8 3.5 25 4.7 0.0 5.2 6 1 0 6 6 5 0 Rad17 P-loop domain AAA_25 PF13481.6 KIK46304.1 - 0.02 14.5 0.0 0.68 9.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain Prefoldin_3 PF13758.6 KIK46304.1 - 0.08 13.0 4.6 0.21 11.7 1.6 3.1 2 0 0 2 2 2 0 Prefoldin subunit RuvB_N PF05496.12 KIK46304.1 - 0.08 12.7 0.1 4 7.2 0.0 3.2 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 KIK46304.1 - 0.11 12.4 1.0 38 4.2 0.1 4.4 4 0 0 4 4 3 0 NACHT domain TsaE PF02367.17 KIK46304.1 - 0.12 12.4 0.8 20 5.2 0.0 3.8 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 KIK46304.1 - 0.13 11.8 1.9 42 3.7 0.1 3.8 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 KIK46304.1 - 0.14 11.9 0.3 11 5.8 0.1 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation dNK PF01712.19 KIK46304.1 - 0.23 11.3 1.6 0.81 9.5 0.5 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase YabA PF06156.13 KIK46304.1 - 7.6 7.2 17.5 8.1 7.2 6.1 4.1 3 0 0 3 3 3 0 Initiation control protein YabA LSM PF01423.22 KIK46305.1 - 9.6e-14 50.8 0.4 1.3e-13 50.4 0.3 1.3 1 1 0 1 1 1 1 LSM domain Hfq PF17209.3 KIK46305.1 - 0.0045 16.6 0.2 0.0079 15.8 0.2 1.5 1 0 0 1 1 1 1 Hfq protein Pex2_Pex12 PF04757.14 KIK46306.1 - 2.2e-23 83.0 1.1 7.5e-23 81.3 1.1 1.7 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 KIK46306.1 - 1.1e-09 37.9 5.9 1.7e-09 37.4 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK46306.1 - 5.7e-08 32.5 7.9 1.1e-07 31.6 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK46306.1 - 1.9e-07 31.3 10.9 3.2e-07 30.6 10.9 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KIK46306.1 - 2.6e-07 30.4 6.9 4.4e-07 29.7 6.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KIK46306.1 - 1.1e-06 28.4 9.0 1.9e-06 27.6 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK46306.1 - 8.1e-06 25.8 3.8 2.1e-05 24.4 3.8 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIK46306.1 - 2.3e-05 24.2 8.9 3.9e-05 23.5 8.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KIK46306.1 - 2.9e-05 24.3 6.6 5.5e-05 23.4 6.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KIK46306.1 - 0.013 15.5 2.1 0.024 14.7 2.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KIK46306.1 - 0.016 15.3 9.2 0.032 14.4 9.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KIK46306.1 - 0.15 12.2 5.2 0.29 11.3 5.2 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KIK46306.1 - 1.3 8.8 8.4 2.6 7.9 8.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.21 KIK46306.1 - 9 6.6 9.6 28 5.0 9.6 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Romo1 PF10247.9 KIK46307.1 - 9.5e-27 93.2 6.2 1.3e-26 92.8 6.2 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Hexapep PF00132.24 KIK46310.1 - 2.6e-06 26.9 15.0 0.016 14.9 0.1 4.1 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) FapA PF03961.13 KIK46310.1 - 0.058 12.0 1.0 0.065 11.8 1.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Hexapep_2 PF14602.6 KIK46310.1 - 0.45 10.3 12.5 0.51 10.1 4.8 3.4 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase L51_S25_CI-B8 PF05047.16 KIK46311.1 - 1.7e-10 40.6 0.1 3.2e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain CAP_N PF01213.19 KIK46313.1 - 4.8e-05 23.0 26.8 0.00094 18.8 26.8 2.9 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 KIK46313.1 - 0.0021 18.2 3.0 0.0024 18.0 3.0 1.1 1 0 0 1 1 1 1 Mitochondrial fission regulator PRIMA1 PF16101.5 KIK46313.1 - 0.0029 17.6 6.2 0.0044 17.1 6.2 1.3 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 Matrilin_ccoil PF10393.9 KIK46313.1 - 0.048 13.5 0.1 0.074 12.9 0.1 1.3 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin TSKS PF15358.6 KIK46313.1 - 0.14 10.5 0.1 0.17 10.2 0.1 1.0 1 0 0 1 1 1 0 Testis-specific serine kinase substrate RF-1 PF00472.20 KIK46314.1 - 1.3e-21 76.6 3.7 1.3e-21 76.6 3.7 1.9 2 0 0 2 2 2 1 RF-1 domain Linker_histone PF00538.19 KIK46315.1 - 7.2e-24 83.9 1.3 1.8e-23 82.7 0.0 2.2 2 0 0 2 2 2 1 linker histone H1 and H5 family EI24 PF07264.11 KIK46316.1 - 1.1e-38 133.2 11.7 1.5e-38 132.8 11.7 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF4112 PF13430.6 KIK46316.1 - 0.01 16.1 0.3 0.038 14.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4112) tRNA_int_endo PF01974.17 KIK46317.1 - 7.3e-15 54.8 0.0 1.3e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Lipase_GDSL_2 PF13472.6 KIK46318.1 - 3.5e-27 96.0 0.0 4.2e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIK46318.1 - 6.4e-19 68.7 0.0 1e-18 68.1 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Asparaginase PF00710.20 KIK46321.1 - 2.5e-57 193.5 0.0 1.1e-56 191.4 0.0 1.9 1 1 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KIK46321.1 - 6.7e-30 103.6 0.0 1.3e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 KIK46321.1 - 2.1e-10 41.1 0.1 5.6e-10 39.7 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK46321.1 - 1.1e-08 35.4 0.0 1.3e-07 32.0 0.1 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KIK46321.1 - 4.1e-08 33.3 1.2 0.013 15.9 0.3 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KIK46321.1 - 2.6e-07 30.8 1.4 3.9e-06 27.0 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK46321.1 - 1.4e-06 28.2 0.6 0.21 12.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Nsp3_PL2pro PF12124.8 KIK46321.1 - 0.14 12.0 0.1 0.68 9.8 0.1 2.1 2 0 0 2 2 2 0 Coronavirus polyprotein cleavage domain Rhodanese PF00581.20 KIK46324.1 - 3.6e-14 53.2 0.0 6.6e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Cpn60_TCP1 PF00118.24 KIK46325.1 - 5.3e-148 493.7 12.8 5.9e-148 493.5 12.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 KIK46325.1 - 0.0022 17.5 0.0 0.0055 16.2 0.0 1.7 1 0 0 1 1 1 1 Telomere recombination Arteri_nsp7a PF16749.5 KIK46325.1 - 0.059 13.6 0.6 3.7 7.7 0.0 3.0 3 0 0 3 3 3 0 Arterivirus nonstructural protein 7 alpha SCAB_CC PF16712.5 KIK46325.1 - 0.46 10.3 4.4 1.6 8.6 0.1 2.5 2 0 0 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein TPR_1 PF00515.28 KIK46326.1 - 1.4e-27 94.3 3.3 6.4e-08 32.1 0.3 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 KIK46326.1 - 6.1e-27 91.5 12.8 0.00019 21.3 0.2 9.4 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_16 PF13432.6 KIK46326.1 - 2.8e-21 75.9 11.0 2.9e-06 27.8 0.0 7.3 6 2 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK46326.1 - 5.4e-19 68.2 8.3 8.1e-11 42.0 0.2 5.8 3 2 4 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KIK46326.1 - 8.4e-17 60.3 2.0 0.012 16.0 0.1 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIK46326.1 - 6.7e-16 58.6 11.3 1.5e-06 28.7 0.1 6.0 6 2 1 7 7 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK46326.1 - 1.3e-12 46.8 0.1 0.22 11.8 0.1 7.1 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIK46326.1 - 1.5e-12 47.0 0.0 0.53 10.0 0.0 6.9 5 2 2 7 7 7 4 TPR repeat TPR_14 PF13428.6 KIK46326.1 - 1.8e-10 40.7 22.4 0.44 11.5 0.1 9.4 6 1 4 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIK46326.1 - 2.4e-09 37.3 15.9 0.00073 19.8 0.1 7.6 6 1 2 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIK46326.1 - 6.6e-06 26.4 6.6 0.9 10.3 0.0 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 KIK46326.1 - 6.1e-05 22.4 10.6 0.19 10.9 0.2 4.2 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 KIK46326.1 - 0.0013 18.8 17.1 0.14 12.3 0.3 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 KIK46326.1 - 0.0026 18.1 2.1 0.12 12.7 0.1 3.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 KIK46326.1 - 0.003 17.3 0.2 3.2 7.4 0.3 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat-like domain PPTA PF01239.22 KIK46326.1 - 0.015 15.0 0.1 1.8 8.4 0.0 2.6 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat TPR_7 PF13176.6 KIK46326.1 - 0.038 14.0 9.2 1.3 9.2 0.0 5.6 8 0 0 8 8 5 0 Tetratricopeptide repeat Phage_integrase PF00589.22 KIK46326.1 - 0.12 12.1 0.4 3.3 7.5 0.1 2.5 2 0 0 2 2 2 0 Phage integrase family SRR1 PF07985.12 KIK46328.1 - 2.5e-17 62.6 0.1 1.2e-16 60.4 0.3 2.0 2 0 0 2 2 2 1 SRR1 Pre-PUA PF17832.1 KIK46329.1 - 1.8e-24 86.3 0.4 3e-24 85.5 0.2 1.5 2 0 0 2 2 2 1 Pre-PUA-like domain PUA PF01472.20 KIK46329.1 - 1.9e-16 59.7 0.0 2.7e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 KIK46329.1 - 0.0032 17.7 0.0 0.0069 16.7 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1947) CRM1_C PF08767.11 KIK46331.1 - 1.5e-133 445.0 0.1 1.5e-133 445.0 0.1 2.8 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 KIK46331.1 - 6.9e-41 139.8 8.2 3.9e-40 137.3 7.4 2.8 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KIK46331.1 - 2.3e-33 113.7 4.5 5.5e-33 112.4 4.5 1.7 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KIK46331.1 - 1.6e-30 104.9 1.2 1.6e-30 104.9 1.2 3.0 4 0 0 4 4 4 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KIK46331.1 - 2.7e-18 65.2 1.1 2.7e-18 65.2 1.1 2.4 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KIK46331.1 - 7.7e-12 45.0 0.0 2.8e-11 43.2 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 KIK46331.1 - 0.026 14.5 0.1 0.41 10.5 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 KIK46331.1 - 0.089 13.4 1.0 10 6.8 0.0 3.8 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region ADH_zinc_N_2 PF13602.6 KIK46332.1 - 8.3e-22 78.7 0.0 1.6e-21 77.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KIK46332.1 - 1e-11 44.9 0.0 4e-11 43.0 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIK46332.1 - 0.00026 20.8 0.0 0.00061 19.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_N PF08240.12 KIK46332.1 - 0.00094 19.0 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KIK46332.1 - 0.071 12.4 0.2 0.11 11.7 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MHB PF16525.5 KIK46333.1 - 0.1 12.8 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Haemophore, haem-binding E1-E2_ATPase PF00122.20 KIK46336.1 - 1.1e-53 181.4 1.3 1.1e-53 181.4 1.3 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KIK46336.1 - 1.3e-45 155.4 8.1 1.3e-45 155.4 8.1 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KIK46336.1 - 3.8e-21 76.4 1.0 1.1e-19 71.5 1.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KIK46336.1 - 4.1e-21 74.4 0.2 2e-20 72.3 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KIK46336.1 - 2.6e-20 72.3 0.0 5.1e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KIK46336.1 - 4.5e-06 26.6 2.0 5e-06 26.5 0.7 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIK46336.1 - 0.00078 19.9 0.0 0.0018 18.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-C3HC4_3 PF13920.6 KIK46337.1 - 0.0041 17.0 8.8 0.0088 15.9 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CBP4 PF07960.11 KIK46338.1 - 2.3e-09 37.2 0.0 2.4e-09 37.1 0.0 1.0 1 0 0 1 1 1 1 CBP4 TPT PF03151.16 KIK46340.1 - 2.5e-07 30.4 3.2 0.0014 18.0 0.0 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 KIK46340.1 - 2.1e-05 23.9 6.9 3.3e-05 23.2 6.9 1.4 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KIK46340.1 - 5.1e-05 22.6 11.5 8.3e-05 21.9 11.5 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KIK46340.1 - 0.00012 22.3 1.7 0.00012 22.3 1.7 2.6 2 1 0 2 2 2 1 EamA-like transporter family SMP_LBD PF17047.5 KIK46340.1 - 0.055 12.9 0.6 0.12 11.8 0.1 1.7 2 0 0 2 2 2 0 Synaptotagmin-like mitochondrial-lipid-binding domain CPP1-like PF11833.8 KIK46340.1 - 1.9 8.1 4.5 0.32 10.6 0.6 1.7 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like SHQ1 PF04925.15 KIK46341.1 - 8.2e-58 194.9 0.0 1.3e-57 194.2 0.0 1.2 1 0 0 1 1 1 1 SHQ1 protein CS PF04969.16 KIK46341.1 - 4.3e-05 24.5 0.0 7.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 CS domain PIH1_CS PF18201.1 KIK46341.1 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.5 1 0 0 1 1 1 1 PIH1 CS-like domain ArsA_HSP20 PF17886.1 KIK46341.1 - 0.00076 19.0 0.0 0.0017 17.9 0.0 1.6 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Chorismate_bind PF00425.18 KIK46342.1 - 1.8e-78 263.7 0.0 3.1e-78 262.9 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KIK46342.1 - 6.6e-28 97.7 0.0 2e-27 96.2 0.0 1.8 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Ribosomal_S2 PF00318.20 KIK46343.1 - 1.4e-53 181.3 0.0 7.5e-30 103.8 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 HSP70 PF00012.20 KIK46344.1 - 2.5e-205 683.2 4.0 2.7e-205 683.1 4.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIK46344.1 - 4.6e-16 58.5 0.1 7.2e-16 57.9 0.1 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 KIK46344.1 - 0.0086 15.8 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 KIK46344.1 - 0.016 14.2 0.3 0.18 10.7 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Zincin_2 PF10103.9 KIK46344.1 - 0.022 14.0 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase Gag_p24 PF00607.20 KIK46344.1 - 0.063 13.1 0.3 1.1 9.0 0.2 2.2 2 0 0 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) StbA PF06406.11 KIK46344.1 - 0.082 12.1 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 StbA protein ATP-synt_DE PF00401.20 KIK46344.1 - 1 9.7 6.8 4 7.8 4.6 2.6 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain AAA PF00004.29 KIK46345.1 - 8.9e-15 55.3 0.0 2e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KIK46345.1 - 4.8e-11 42.7 0.0 3.5e-09 36.7 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 KIK46345.1 - 3.9e-10 40.0 0.0 1.1e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 KIK46345.1 - 6.4e-08 32.7 0.0 1.6e-07 31.4 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KIK46345.1 - 1.1e-05 25.7 0.0 3.9e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KIK46345.1 - 2.3e-05 24.6 0.0 5.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 KIK46345.1 - 0.0001 22.2 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK46345.1 - 0.00011 22.7 0.0 0.00047 20.6 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KIK46345.1 - 0.00056 19.9 0.0 0.0019 18.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KIK46345.1 - 0.00076 19.3 0.0 0.0019 18.0 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KIK46345.1 - 0.0014 18.2 0.0 0.0033 17.0 0.0 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 KIK46345.1 - 0.0016 18.2 0.0 0.0038 17.0 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 KIK46345.1 - 0.0019 18.0 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KIK46345.1 - 0.0047 16.3 0.0 0.1 12.0 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.15 KIK46345.1 - 0.0086 16.1 0.0 0.063 13.3 0.0 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KIK46345.1 - 0.0096 16.3 0.0 0.049 14.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KIK46345.1 - 0.012 15.9 0.0 0.067 13.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KIK46345.1 - 0.013 14.8 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DNA_pol3_delta PF06144.13 KIK46345.1 - 0.034 13.9 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_2 PF07724.14 KIK46345.1 - 0.057 13.5 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DEAD PF00270.29 KIK46345.1 - 0.072 12.9 0.0 0.67 9.7 0.0 2.1 1 1 0 2 2 2 0 DEAD/DEAH box helicase PhoH PF02562.16 KIK46345.1 - 0.079 12.4 0.1 2.2 7.7 0.0 2.4 3 0 0 3 3 3 0 PhoH-like protein AAA_23 PF13476.6 KIK46345.1 - 0.086 13.3 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK46345.1 - 0.13 12.8 0.0 0.27 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 KIK46345.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 KIK46345.1 - 0.17 11.0 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 KIK46345.1 - 0.17 12.3 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase CAF1A PF12253.8 KIK46346.1 - 4.6e-22 78.0 4.0 4.6e-22 78.0 4.0 2.7 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A Peptidase_S49_N PF08496.10 KIK46346.1 - 3.4 7.7 12.4 0.74 9.9 6.7 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal EMC3_TMCO1 PF01956.16 KIK46346.1 - 6 6.6 5.7 20 4.8 2.6 2.2 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Spc24 PF08286.11 KIK46347.1 - 3.8e-19 68.9 0.1 1.2e-18 67.3 0.0 1.8 2 1 0 2 2 2 1 Spc24 subunit of Ndc80 MbeD_MobD PF04899.12 KIK46347.1 - 0.044 13.9 0.1 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 MbeD/MobD like AAA_13 PF13166.6 KIK46347.1 - 0.19 10.3 3.1 2.4 6.7 0.4 1.9 1 1 1 2 2 2 0 AAA domain RCC1 PF00415.18 KIK46348.1 - 5e-22 78.3 12.4 2.1e-08 34.6 0.1 7.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KIK46348.1 - 5.6e-14 51.5 20.9 1.4e-08 34.3 0.1 6.7 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat DUF5086 PF16985.5 KIK46348.1 - 0.12 12.3 0.6 0.21 11.5 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5086) DUF883 PF05957.13 KIK46348.1 - 0.17 12.5 0.5 0.7 10.5 0.3 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) HHV-5_US34A PF17087.5 KIK46349.1 - 0.16 12.2 2.3 0.38 10.9 2.3 1.7 1 0 0 1 1 1 0 Herpesvirus US34A protein family DUF3074 PF11274.8 KIK46350.1 - 7.6e-42 143.4 0.0 9.4e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Ribosomal_L27 PF01016.19 KIK46351.1 - 1.9e-33 114.3 1.1 2.6e-33 113.9 1.1 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein ECR1_N PF14382.6 KIK46351.1 - 0.024 14.4 0.8 0.071 12.9 0.1 2.2 3 0 0 3 3 3 0 Exosome complex exonuclease RRP4 N-terminal region LIM PF00412.22 KIK46352.1 - 2.6e-18 66.0 20.3 3.9e-11 43.0 5.6 3.3 3 0 0 3 3 3 3 LIM domain DUF2321 PF10083.9 KIK46352.1 - 0.17 11.5 2.8 0.35 10.5 2.8 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Fungal_trans PF04082.18 KIK46353.1 - 4.5e-22 78.4 0.2 2.9e-21 75.7 0.2 2.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK46353.1 - 1.5e-10 41.1 3.8 3.8e-10 39.7 3.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHHC PF01529.20 KIK46354.1 - 2.2e-33 115.2 11.2 2.2e-33 115.2 11.2 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF35_N PF12172.8 KIK46354.1 - 0.087 12.7 2.5 0.3 11.0 2.5 1.9 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) CTP_transf_like PF01467.26 KIK46355.1 - 4.1e-09 36.8 0.0 8.5e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 KIK46355.1 - 0.09 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 FAD synthetase Lipase_3 PF01764.25 KIK46356.1 - 2.2e-06 27.6 0.0 7e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIK46356.1 - 0.0037 17.9 3.4 0.0056 17.3 2.4 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family UPF0227 PF05728.12 KIK46356.1 - 0.0053 16.7 0.0 0.0084 16.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Amidohydro_1 PF01979.20 KIK46357.1 - 6.5e-64 216.4 0.1 3.2e-54 184.5 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KIK46357.1 - 2.1e-05 24.2 0.6 0.25 10.8 0.1 2.9 2 1 0 2 2 2 2 Amidohydrolase family mRNA_cap_enzyme PF01331.19 KIK46359.1 - 6.2e-52 176.3 0.0 9.2e-52 175.7 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KIK46359.1 - 1.6e-29 102.7 0.0 2.7e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KIK46359.1 - 8.8e-10 38.6 0.0 5.9e-06 26.1 0.0 2.2 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 KIK46359.1 - 0.00023 21.5 0.2 0.0004 20.7 0.0 1.6 2 0 0 2 2 2 1 RNA ligase Skp1 PF01466.19 KIK46360.1 - 1.8e-28 98.4 0.2 2.8e-28 97.8 0.2 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KIK46360.1 - 1.1e-22 79.9 0.6 1.1e-22 79.9 0.6 2.0 3 0 0 3 3 3 1 Skp1 family, tetramerisation domain BTB PF00651.31 KIK46360.1 - 0.036 14.3 0.0 3 8.1 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain Syja_N PF02383.18 KIK46361.1 - 1e-91 307.6 0.0 1.5e-91 307.1 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KIK46361.1 - 3.7e-25 87.9 0.0 6.7e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase Proteasome PF00227.26 KIK46362.1 - 2.4e-49 167.4 0.1 2.9e-49 167.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Cys_Met_Meta_PP PF01053.20 KIK46363.1 - 4.1e-50 170.4 0.0 1.3e-49 168.7 0.0 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme FMO-like PF00743.19 KIK46364.1 - 5.8e-35 120.7 0.0 1.7e-24 86.1 0.0 2.9 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIK46364.1 - 3.8e-14 52.7 0.1 3.8e-10 39.5 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK46364.1 - 7.9e-13 48.3 0.0 2.8e-10 39.9 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIK46364.1 - 3.9e-06 26.9 1.1 0.0021 18.1 0.1 3.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KIK46364.1 - 0.00072 19.7 0.0 0.0019 18.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KIK46364.1 - 0.0012 18.0 0.0 0.013 14.6 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) UQ_con PF00179.26 KIK46365.1 - 1.3e-49 167.4 0.0 1.5e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIK46365.1 - 0.0013 18.4 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KIK46365.1 - 0.018 15.3 0.7 0.03 14.6 0.7 1.6 1 1 0 1 1 1 0 RWD domain F-box PF00646.33 KIK46366.1 - 5.3e-07 29.4 0.1 1e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK46366.1 - 1.6e-05 24.7 0.0 3.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIK46366.1 - 0.2 11.6 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 F-box VHL PF01847.16 KIK46367.1 - 0.06 13.3 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 VHL beta domain TetR_C_27 PF17935.1 KIK46367.1 - 0.077 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF1713 PF08213.11 KIK46369.1 - 5.5e-08 32.6 21.7 7.9e-08 32.1 21.7 1.2 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Glyco_transf_22 PF03901.17 KIK46370.1 - 1.3e-84 284.9 18.7 1.5e-84 284.7 18.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3835 PF12927.7 KIK46371.1 - 1.3e-08 35.6 8.6 1.1e-06 29.4 0.8 4.0 4 1 0 4 4 4 2 Domain of unknown function (DUF3835) DUF3090 PF11290.8 KIK46371.1 - 0.31 10.9 1.4 5.7 6.7 0.0 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF3090) KH_8 PF17903.1 KIK46372.1 - 0.0013 18.8 0.0 0.0036 17.4 0.0 1.7 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 KIK46372.1 - 0.002 17.9 0.8 0.0045 16.8 0.8 1.6 1 0 0 1 1 1 1 KH domain MCPVI PF02993.14 KIK46372.1 - 0.093 12.5 0.3 0.13 12.1 0.3 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Glyoxal_oxid_N PF07250.11 KIK46373.1 - 7.2e-34 117.0 0.0 8.8e-33 113.5 0.0 2.6 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KIK46373.1 - 2.7e-23 82.1 0.1 7.2e-23 80.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) CE2_N PF17996.1 KIK46373.1 - 0.0091 16.0 0.0 0.027 14.4 0.0 1.7 2 0 0 2 2 2 1 Carbohydrate esterase 2 N-terminal Kelch_4 PF13418.6 KIK46373.1 - 0.029 14.4 0.0 4.1 7.5 0.0 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain WD40 PF00400.32 KIK46374.1 - 5.4e-28 96.7 15.5 1.1e-06 29.2 0.1 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK46374.1 - 2.5e-06 27.7 2.7 1.8 8.9 0.0 4.5 3 2 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KIK46374.1 - 0.001 18.1 0.9 0.15 11.0 0.1 3.7 4 0 0 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 KIK46374.1 - 0.043 12.8 0.0 0.077 11.9 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 KIK46374.1 - 0.087 11.8 0.0 0.57 9.2 0.0 2.3 3 0 0 3 3 3 0 Coatomer WD associated region Metallothio_Pro PF02069.16 KIK46375.1 - 0.17 12.1 1.1 0.33 11.2 1.1 1.4 1 0 0 1 1 1 0 Prokaryotic metallothionein PLATZ PF04640.14 KIK46375.1 - 0.28 11.8 2.7 0.65 10.7 1.9 2.1 2 0 0 2 2 2 0 PLATZ transcription factor Vps54 PF07928.12 KIK46376.1 - 2.6e-51 173.6 0.1 7.2e-51 172.1 0.1 1.8 1 0 0 1 1 1 1 Vps54-like protein DUF2451 PF10474.9 KIK46376.1 - 2.4e-05 24.3 1.1 4.6e-05 23.3 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) GST_C_6 PF17171.4 KIK46377.1 - 9.5e-15 54.2 0.1 2.9e-14 52.6 0.0 1.9 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK46377.1 - 0.0041 17.1 0.0 0.0091 16.0 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KIK46377.1 - 0.014 16.1 0.0 0.026 15.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain SAM35 PF10806.8 KIK46377.1 - 0.21 11.8 1.5 0.48 10.7 0.8 1.8 2 0 0 2 2 2 0 SAM35, subunit of SAM coomplex TRAM_LAG1_CLN8 PF03798.16 KIK46378.1 - 1e-31 110.2 15.8 1.4e-31 109.8 15.8 1.2 1 0 0 1 1 1 1 TLC domain SLC3A2_N PF16028.5 KIK46378.1 - 0.25 10.9 0.0 0.25 10.9 0.0 2.0 3 0 0 3 3 3 0 Solute carrier family 3 member 2 N-terminus G-gamma PF00631.22 KIK46379.1 - 3.6e-25 87.7 0.0 4e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 GGL domain COG5 PF10392.9 KIK46379.1 - 0.083 13.1 0.3 0.096 12.9 0.3 1.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 G-gamma PF00631.22 KIK46382.1 - 6.9e-21 74.0 0.0 7.8e-21 73.9 0.0 1.0 1 0 0 1 1 1 1 GGL domain Thioredoxin PF00085.20 KIK46383.1 - 1e-21 76.8 0.0 1.3e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KIK46383.1 - 4.1e-08 33.6 0.1 2.2e-07 31.3 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KIK46383.1 - 1.6e-05 25.1 0.0 3.9e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KIK46383.1 - 0.0016 18.4 0.0 0.0019 18.1 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KIK46383.1 - 0.0068 16.6 0.0 0.0099 16.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Pullulanase_Ins PF18494.1 KIK46383.1 - 0.069 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 Pullulanase Ins domain CBF PF03914.17 KIK46384.1 - 1.3e-27 96.9 4.8 5.3e-26 91.7 2.2 2.9 3 0 0 3 3 3 2 CBF/Mak21 family MOR2-PAG1_C PF14225.6 KIK46384.1 - 0.0023 17.8 0.1 0.0046 16.8 0.1 1.4 1 0 0 1 1 1 1 Cell morphogenesis C-terminal GyrI-like PF06445.15 KIK46384.1 - 0.026 14.8 0.0 0.078 13.3 0.0 1.8 2 0 0 2 2 2 0 GyrI-like small molecule binding domain Myotub-related PF06602.14 KIK46385.1 - 1.9e-148 494.1 0.0 2.5e-148 493.7 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 KIK46385.1 - 0.0056 16.7 0.1 0.02 14.8 0.1 2.0 1 1 0 1 1 1 1 Tyrosine phosphatase family GRAM PF02893.20 KIK46385.1 - 0.031 14.2 0.0 0.085 12.7 0.0 1.7 1 0 0 1 1 1 0 GRAM domain Y_phosphatase PF00102.27 KIK46385.1 - 0.077 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 KIK46385.1 - 0.21 11.4 0.0 0.56 10.0 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain S-AdoMet_synt_C PF02773.16 KIK46386.1 - 2.6e-67 225.1 0.3 7.2e-67 223.6 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KIK46386.1 - 1.6e-46 157.4 0.0 3e-46 156.5 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KIK46386.1 - 5.1e-45 152.2 0.6 8e-45 151.6 0.1 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 KIK46386.1 - 0.036 12.9 0.2 0.17 10.6 0.1 1.9 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) GATase_6 PF13522.6 KIK46387.1 - 8.4e-13 48.7 0.0 1.7e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KIK46387.1 - 1.1e-08 34.8 0.1 1.9e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.6 KIK46387.1 - 1.2e-08 34.9 0.0 2.1e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KIK46387.1 - 2.7e-05 23.2 0.0 0.00016 20.7 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferases class-II PorB PF11565.8 KIK46387.1 - 0.044 14.2 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Alpha helical Porin B AP_endonuc_2 PF01261.24 KIK46387.1 - 0.16 11.3 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel cwf18 PF08315.12 KIK46388.1 - 1e-33 116.9 7.3 1.7e-33 116.2 7.3 1.3 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor PGM1_C PF18105.1 KIK46388.1 - 0.29 10.7 1.1 1.4 8.5 0.1 2.2 2 0 0 2 2 2 0 PGM1 C-terminal domain GTP_EFTU PF00009.27 KIK46389.1 - 5.5e-48 163.1 0.1 8.5e-48 162.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KIK46389.1 - 1.9e-44 150.2 0.2 3.7e-44 149.3 0.2 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KIK46389.1 - 6.1e-18 64.7 0.0 1.4e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KIK46389.1 - 1.4e-08 35.0 0.1 2.7e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIK46389.1 - 3.7e-06 27.0 0.2 1.5e-05 25.0 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase EFG_II PF14492.6 KIK46389.1 - 7.7e-05 22.7 0.0 0.00028 20.9 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II RF3_C PF16658.5 KIK46389.1 - 8.6e-05 22.4 0.0 0.00023 21.0 0.0 1.7 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain Ras PF00071.22 KIK46389.1 - 0.00093 18.8 0.0 0.0026 17.4 0.0 1.7 2 0 0 2 2 2 1 Ras family SRPRB PF09439.10 KIK46389.1 - 0.13 11.7 0.1 0.35 10.3 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit IF-2B PF01008.17 KIK46390.1 - 2e-65 220.8 0.1 2.5e-65 220.5 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Porin_O_P PF07396.11 KIK46390.1 - 0.057 12.6 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphate-selective porin O and P rve PF00665.26 KIK46390.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain WW PF00397.26 KIK46391.1 - 0.0046 17.0 1.6 0.0088 16.1 1.6 1.5 1 0 0 1 1 1 1 WW domain Dsh_C PF12316.8 KIK46391.1 - 0.006 17.0 6.6 0.0087 16.5 6.6 1.2 1 0 0 1 1 1 1 Segment polarity protein dishevelled (Dsh) C terminal DUF2076 PF09849.9 KIK46391.1 - 0.042 13.9 8.4 0.079 13.0 8.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CDC45 PF02724.14 KIK46391.1 - 0.18 10.1 0.7 0.2 9.9 0.7 1.0 1 0 0 1 1 1 0 CDC45-like protein TRAPPC-Trs85 PF12739.7 KIK46392.1 - 1.7e-29 103.0 0.0 2.2e-25 89.5 0.0 2.3 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.11 KIK46392.1 - 0.0037 14.7 0.0 0.0056 14.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Mpv17_PMP22 PF04117.12 KIK46393.1 - 1.6e-10 41.1 1.0 2.7e-10 40.3 1.0 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mito_carr PF00153.27 KIK46394.1 - 8.1e-30 102.6 8.5 4.4e-15 55.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1664 PF07889.12 KIK46396.1 - 0.00061 19.8 53.2 0.016 15.3 1.0 8.2 3 1 3 8 8 8 6 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 KIK46396.1 - 0.001 19.2 6.4 0.001 19.2 6.4 9.5 1 1 7 8 8 8 1 TATA element modulatory factor 1 TATA binding Filament PF00038.21 KIK46396.1 - 0.0016 18.1 95.5 0.032 13.8 30.9 4.6 1 1 2 3 3 3 2 Intermediate filament protein Lectin_N PF03954.14 KIK46396.1 - 0.0044 16.8 0.7 0.0044 16.8 0.7 7.9 4 2 3 8 8 8 1 Hepatic lectin, N-terminal domain Spc7 PF08317.11 KIK46396.1 - 1.9 7.3 108.2 0.27 10.1 5.7 6.9 1 1 8 9 9 9 0 Spc7 kinetochore protein His_Phos_1 PF00300.22 KIK46397.1 - 4e-39 134.3 0.0 5.2e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pep3_Vps18 PF05131.14 KIK46398.1 - 1.6e-48 164.3 0.0 3.2e-48 163.3 0.0 1.5 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KIK46398.1 - 4.3e-10 39.6 2.2 9.4e-05 22.3 0.0 3.1 3 1 0 3 3 2 2 Region in Clathrin and VPS zf-RING_5 PF14634.6 KIK46398.1 - 2.5e-05 24.1 1.9 4.2e-05 23.4 0.4 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Vps39_2 PF10367.9 KIK46398.1 - 3e-05 24.4 0.0 8.8e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_11 PF17123.5 KIK46398.1 - 6e-05 22.7 4.5 6.9e-05 22.5 3.0 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KIK46398.1 - 0.00038 20.2 1.3 0.00038 20.2 1.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK46398.1 - 0.00047 20.4 4.0 0.00048 20.4 1.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KIK46398.1 - 0.00088 19.3 1.6 0.0027 17.7 1.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KIK46398.1 - 0.0036 16.9 0.4 0.0036 16.9 0.4 2.3 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type Egg_lysin PF01303.17 KIK46398.1 - 0.094 12.9 0.1 0.24 11.6 0.1 1.7 1 0 0 1 1 1 0 Egg lysin (Sperm-lysin) DUF1664 PF07889.12 KIK46398.1 - 0.16 12.0 0.6 0.51 10.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PspA_IM30 PF04012.12 KIK46398.1 - 0.19 11.3 0.7 4.3 6.8 0.1 2.3 2 0 0 2 2 2 0 PspA/IM30 family zf-rbx1 PF12678.7 KIK46398.1 - 1.6 9.1 3.2 1.6 9.0 0.4 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KIK46398.1 - 1.9 8.4 5.6 0.27 11.2 0.9 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cgr1 PF03879.14 KIK46399.1 - 2.5e-29 101.8 24.3 2.8e-29 101.7 24.3 1.0 1 0 0 1 1 1 1 Cgr1 family DUF3682 PF12446.8 KIK46399.1 - 0.24 11.9 3.9 0.31 11.5 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Ribosomal_L44 PF00935.19 KIK46399.1 - 3.6 8.1 16.3 5 7.7 7.5 2.7 1 1 0 2 2 2 0 Ribosomal protein L44 DUF1682 PF07946.14 KIK46399.1 - 6.5 5.9 14.6 6.9 5.8 14.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PEARLI-4 PF05278.12 KIK46399.1 - 9.5 5.7 11.9 12 5.3 11.9 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) TolA_bind_tri PF16331.5 KIK46400.1 - 0.046 13.8 0.7 0.083 13.0 0.7 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF3573 PF12097.8 KIK46400.1 - 0.072 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF3450 PF11932.8 KIK46400.1 - 0.14 11.5 0.5 0.22 10.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-RING_7 PF02591.15 KIK46400.1 - 0.16 12.1 0.3 0.38 11.0 0.3 1.6 1 0 0 1 1 1 0 C4-type zinc ribbon domain DivIC PF04977.15 KIK46400.1 - 0.59 9.9 2.0 1.2 9.0 2.0 1.4 1 0 0 1 1 1 0 Septum formation initiator Sec39 PF08314.11 KIK46401.1 - 6.4e-97 325.8 0.0 1.5e-96 324.6 0.0 1.5 2 0 0 2 2 2 1 Secretory pathway protein Sec39 F-box-like PF12937.7 KIK46402.1 - 7.8e-08 32.1 3.2 2.5e-06 27.3 3.2 2.9 1 1 0 1 1 1 1 F-box-like DUF1478 PF07349.11 KIK46402.1 - 0.04 13.8 0.5 0.14 12.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1478) LRR_4 PF12799.7 KIK46402.1 - 3.8 8.1 4.6 2.1 8.9 0.3 2.8 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) UPF0113_N PF17833.1 KIK46403.1 - 2.5e-29 101.6 0.0 3.8e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KIK46403.1 - 9.7e-26 89.8 0.0 1.6e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain HpuA PF16960.5 KIK46403.1 - 0.14 11.3 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Haemoglobin-haptoglobin utilisation, porphyrin transporter NRDE-2 PF08424.10 KIK46404.1 - 2.1e-68 230.8 0.1 3.9e-68 229.9 0.1 1.4 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KIK46404.1 - 0.29 12.1 8.6 64 4.8 0.0 6.0 6 1 1 7 7 7 0 Tetratricopeptide repeat UreD PF01774.17 KIK46406.1 - 1e-66 224.9 0.0 1.2e-66 224.7 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein ASH PF15780.5 KIK46406.1 - 0.075 13.2 0.0 19 5.6 0.0 2.3 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin MFS_1 PF07690.16 KIK46407.1 - 7.1e-31 107.4 32.3 7.4e-30 104.1 33.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_M41 PF01434.18 KIK46408.1 - 5.2e-62 209.1 0.0 7.9e-62 208.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KIK46408.1 - 1.5e-42 145.2 0.0 2.9e-42 144.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIK46408.1 - 3.2e-14 52.5 0.1 9.3e-14 51.0 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KIK46408.1 - 1.4e-09 38.3 0.0 3.6e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular TIP49 PF06068.13 KIK46408.1 - 0.0035 16.6 0.0 0.0061 15.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 KIK46408.1 - 0.0049 17.3 0.1 0.08 13.3 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK46408.1 - 0.016 15.5 0.1 0.62 10.3 0.1 2.5 1 1 1 2 2 2 0 AAA domain RuvB_N PF05496.12 KIK46408.1 - 0.025 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KIK46408.1 - 0.033 14.2 0.1 0.15 12.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIK46408.1 - 0.033 14.3 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KIK46408.1 - 0.035 13.8 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KIK46408.1 - 0.19 11.1 0.2 0.43 9.9 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ANAPC4_WD40 PF12894.7 KIK46409.1 - 8.9e-08 32.3 0.1 1.7 9.0 0.0 4.8 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK46409.1 - 0.0023 17.8 0.0 12 5.7 0.0 4.1 4 0 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KIK46409.1 - 1.3 10.0 6.7 14 6.8 0.2 4.7 5 1 0 5 5 5 0 WD domain, G-beta repeat MFS_1 PF07690.16 KIK46410.1 - 4.9e-40 137.5 45.2 2.4e-39 135.2 44.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK46410.1 - 1.1e-13 50.5 5.1 1.3e-13 50.3 0.3 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIK46410.1 - 9.3e-13 47.8 7.3 9.3e-13 47.8 7.3 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KIK46410.1 - 4.9e-09 35.9 2.0 4.9e-09 35.9 2.0 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Ribosomal_S17 PF00366.20 KIK46411.1 - 1.5e-20 73.0 0.6 1.8e-20 72.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 RdRP PF05183.12 KIK46412.1 - 1.8e-116 390.1 0.0 2.3e-116 389.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase KAP PF05804.12 KIK46412.1 - 0.11 10.6 0.0 0.16 10.1 0.0 1.1 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) Prefoldin_2 PF01920.20 KIK46413.1 - 2.5e-20 72.4 10.6 4e-20 71.7 10.6 1.4 1 0 0 1 1 1 1 Prefoldin subunit DUF4164 PF13747.6 KIK46413.1 - 7.5e-05 22.9 3.3 0.059 13.7 0.1 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4164) End3 PF12761.7 KIK46413.1 - 0.012 15.7 4.5 0.018 15.2 4.5 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 HalX PF08663.10 KIK46413.1 - 0.02 15.2 3.3 0.56 10.6 0.5 2.6 2 1 0 2 2 2 0 HalX domain Prefoldin PF02996.17 KIK46413.1 - 0.032 14.2 5.4 0.33 10.9 2.9 2.1 2 0 0 2 2 2 0 Prefoldin subunit ABC_tran_CTD PF16326.5 KIK46413.1 - 0.043 14.1 10.4 1 9.7 0.4 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain Occludin_ELL PF07303.13 KIK46413.1 - 0.048 14.4 0.8 0.048 14.4 0.8 2.1 1 1 1 2 2 2 0 Occludin homology domain DUF1664 PF07889.12 KIK46413.1 - 0.08 13.0 3.7 0.15 12.1 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Rx_N PF18052.1 KIK46413.1 - 0.12 12.6 4.4 0.1 12.9 0.9 2.2 2 1 0 2 2 2 0 Rx N-terminal domain ADIP PF11559.8 KIK46413.1 - 0.2 11.7 9.9 0.09 12.9 1.7 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Tektin PF03148.14 KIK46413.1 - 0.21 10.3 8.3 0.1 11.3 2.8 2.0 2 0 0 2 2 2 0 Tektin family DUF4407 PF14362.6 KIK46413.1 - 0.24 10.7 2.9 0.31 10.3 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 KIK46413.1 - 0.26 11.8 8.0 1.6 9.3 0.4 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region MCU PF04678.13 KIK46413.1 - 0.27 11.3 2.1 0.49 10.5 2.1 1.5 1 1 0 1 1 1 0 Mitochondrial calcium uniporter ZapB PF06005.12 KIK46413.1 - 0.3 11.5 9.9 14 6.2 9.9 2.2 1 1 0 1 1 1 0 Cell division protein ZapB Spc7 PF08317.11 KIK46413.1 - 1.1 8.0 13.5 15 4.4 13.5 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Spc24 PF08286.11 KIK46413.1 - 1.2 9.5 10.7 6 7.2 1.6 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 YabA PF06156.13 KIK46413.1 - 6 7.6 8.0 59 4.4 8.0 2.0 1 1 0 1 1 1 0 Initiation control protein YabA G_glu_transpept PF01019.21 KIK46414.1 - 2.3e-140 468.8 0.0 2.6e-140 468.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase PP2C PF00481.21 KIK46415.1 - 2.4e-35 122.4 0.0 7.1e-34 117.6 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C His_Phos_2 PF00328.22 KIK46416.1 - 8.3e-51 173.5 0.0 1.1e-50 173.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Git3 PF11710.8 KIK46417.1 - 3.2e-07 30.3 11.6 8.8e-06 25.6 11.6 2.2 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KIK46417.1 - 0.011 15.9 0.1 0.011 15.9 0.1 2.9 3 1 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term Snf7 PF03357.21 KIK46418.1 - 2.5e-30 105.4 12.4 3e-30 105.1 12.4 1.0 1 0 0 1 1 1 1 Snf7 Activator_LAG-3 PF11498.8 KIK46418.1 - 1.6 7.6 7.6 1.2 8.0 0.1 2.0 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Pro_isomerase PF00160.21 KIK46419.1 - 8.2e-43 146.4 0.0 1.3e-42 145.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 KIK46419.1 - 0.0081 16.3 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 KIK46419.1 - 0.11 11.9 0.2 4 6.7 0.0 2.6 2 1 0 2 2 2 0 Rtf2 RING-finger PPR_2 PF13041.6 KIK46420.1 - 1.4e-39 134.1 0.0 9.9e-07 28.9 0.0 8.6 5 2 4 9 9 9 8 PPR repeat family PPR_3 PF13812.6 KIK46420.1 - 6.4e-28 96.6 0.0 4.7e-07 29.8 0.0 5.0 4 1 0 4 4 4 4 Pentatricopeptide repeat domain PPR PF01535.20 KIK46420.1 - 3.3e-16 58.3 2.5 0.62 10.4 0.0 10.4 12 0 0 12 12 12 3 PPR repeat PPR_1 PF12854.7 KIK46420.1 - 2.8e-15 55.7 0.9 0.25 11.1 0.0 8.9 9 0 0 9 9 9 5 PPR repeat PPR_long PF17177.4 KIK46420.1 - 8.4e-08 31.8 0.0 0.019 14.4 0.0 4.5 2 1 1 5 5 5 2 Pentacotripeptide-repeat region of PRORP TPR_16 PF13432.6 KIK46420.1 - 0.025 15.2 0.0 31 5.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Sugar_tr PF00083.24 KIK46422.1 - 2.6e-103 346.3 16.1 3.1e-103 346.1 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK46422.1 - 7.6e-25 87.6 42.3 5.1e-24 84.8 22.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DEAD PF00270.29 KIK46423.1 - 3.6e-15 56.2 0.0 1.2e-14 54.4 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK46423.1 - 4.5e-08 33.4 0.0 3.8e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4203 PF13886.6 KIK46424.1 - 2.7e-50 170.8 26.4 2.7e-50 170.8 26.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) LAG1-DNAbind PF09271.11 KIK46426.1 - 3.6e-27 95.9 0.1 2.1e-24 86.9 0.1 2.4 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 KIK46426.1 - 7.7e-23 81.4 0.0 1.6e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain PK PF00224.21 KIK46427.1 - 7.6e-164 544.6 0.1 1e-163 544.2 0.1 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KIK46427.1 - 6.9e-39 132.7 0.1 2e-38 131.2 0.1 1.8 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KIK46427.1 - 0.00027 20.1 0.1 0.0005 19.3 0.1 1.5 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KIK46427.1 - 0.004 16.2 0.1 0.01 14.8 0.0 1.6 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain DUF5415 PF17436.2 KIK46427.1 - 0.18 11.9 0.0 0.46 10.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5415) Gly_transf_sug PF04488.15 KIK46428.1 - 2.2e-06 28.2 0.0 6.7e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KIK46428.1 - 0.053 12.9 0.2 0.081 12.3 0.2 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 KIK46429.1 - 2.4e-05 24.9 0.0 5.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KIK46429.1 - 0.034 13.5 0.3 0.058 12.8 0.3 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Ribul_P_3_epim PF00834.19 KIK46430.1 - 8.8e-61 204.8 0.0 1e-60 204.5 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PG_binding_3 PF09374.10 KIK46430.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Predicted Peptidoglycan domain COX6A PF02046.15 KIK46432.1 - 1.5e-30 106.0 0.1 1.7e-30 105.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa RPN2_C PF18004.1 KIK46433.1 - 4.8e-42 143.6 1.9 2e-40 138.4 1.9 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KIK46433.1 - 4.2e-32 108.9 25.1 7.3e-08 32.5 0.0 9.2 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KIK46433.1 - 2.9e-20 72.5 0.3 2e-13 50.5 0.0 5.1 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 KIK46433.1 - 0.00012 22.1 0.2 3 8.3 0.1 4.0 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 KIK46433.1 - 0.015 15.8 3.8 3.8 8.1 0.1 4.8 4 1 2 6 6 6 0 HEAT-like repeat ANAPC3 PF12895.7 KIK46433.1 - 0.07 13.4 0.4 0.31 11.3 0.4 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 COQ7 PF03232.13 KIK46433.1 - 0.12 12.2 0.1 0.38 10.5 0.1 1.8 1 1 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Arm PF00514.23 KIK46434.1 - 5.3e-92 299.4 14.6 2.8e-13 49.4 0.1 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KIK46434.1 - 3.6e-25 88.2 3.0 6.6e-25 87.4 3.0 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 KIK46434.1 - 1.4e-24 86.2 2.7 5.2e-09 36.4 0.1 5.8 3 1 3 6 6 6 5 HEAT-like repeat Arm_3 PF16186.5 KIK46434.1 - 4.5e-21 74.1 0.8 9.1e-21 73.2 0.8 1.5 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 KIK46434.1 - 4.2e-16 59.1 2.5 8.9e-05 22.8 0.0 5.2 2 1 4 7 7 6 3 HEAT repeats HEAT PF02985.22 KIK46434.1 - 1.5e-15 55.9 0.5 0.00031 20.7 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat Arm_2 PF04826.13 KIK46434.1 - 1.9e-06 27.6 0.1 0.34 10.3 0.0 4.1 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.20 KIK46434.1 - 4.6e-06 25.5 0.0 0.0015 17.2 0.0 2.9 1 1 2 3 3 3 1 Adaptin N terminal region RICTOR_V PF14668.6 KIK46434.1 - 3e-05 24.2 2.8 0.028 14.6 0.0 4.3 3 2 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 KIK46434.1 - 0.0011 19.0 0.0 0.54 10.4 0.0 3.6 3 3 1 4 4 4 1 V-ATPase subunit H HEAT_PBS PF03130.16 KIK46434.1 - 0.0029 18.1 1.3 0.69 10.8 0.1 4.4 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Mo25 PF08569.11 KIK46434.1 - 0.093 12.1 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 Mo25-like RNF111_N PF15303.6 KIK46434.1 - 0.26 11.0 1.7 0.39 10.5 1.7 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus LSM PF01423.22 KIK46435.1 - 8.2e-22 76.7 0.1 9.1e-22 76.5 0.1 1.0 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 KIK46435.1 - 0.042 14.0 0.0 0.047 13.8 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain SM-ATX PF14438.6 KIK46435.1 - 0.045 13.9 0.0 0.052 13.7 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain Ribosomal_S16 PF00886.19 KIK46436.1 - 8e-23 80.3 0.0 1.1e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 ACBP PF00887.19 KIK46437.1 - 1.5e-14 54.0 0.2 2.2e-14 53.4 0.2 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_5 PF13857.6 KIK46437.1 - 2.4e-09 37.3 0.2 4.2e-09 36.5 0.2 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK46437.1 - 5e-08 33.4 0.1 9.9e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIK46437.1 - 5e-06 26.7 1.2 0.00024 21.4 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KIK46437.1 - 6.3e-06 26.6 0.1 1.1e-05 25.9 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK46437.1 - 2e-05 24.6 0.4 0.00065 20.0 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ligase_CoA PF00549.19 KIK46438.1 - 2.1e-23 82.8 0.1 3.2e-23 82.2 0.1 1.3 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 KIK46438.1 - 6.4e-19 68.4 0.3 6.4e-19 68.4 0.3 2.1 3 0 0 3 3 3 1 CoA binding domain Succ_CoA_lig PF13607.6 KIK46438.1 - 4.7e-10 39.4 0.1 1.4e-09 37.9 0.0 1.7 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KIK46438.1 - 1.5e-05 25.4 1.3 5.6e-05 23.6 0.1 2.5 3 1 0 3 3 3 1 CoA binding domain Peptidase_S66 PF02016.15 KIK46438.1 - 0.011 15.9 0.0 0.031 14.4 0.0 1.7 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain GFO_IDH_MocA PF01408.22 KIK46438.1 - 0.06 14.2 0.1 0.26 12.1 0.0 2.0 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NTPase_1 PF03266.15 KIK46438.1 - 0.077 12.9 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 NTPase Xpo1 PF08389.12 KIK46439.1 - 7.8e-25 87.7 1.2 7.7e-24 84.5 0.0 3.2 4 1 1 5 5 5 1 Exportin 1-like protein IBN_N PF03810.19 KIK46439.1 - 6.3e-07 29.2 0.0 5.6e-06 26.2 0.0 2.7 2 1 1 3 3 3 1 Importin-beta N-terminal domain Cnd1 PF12717.7 KIK46439.1 - 0.0023 18.0 0.0 0.012 15.7 0.0 2.1 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KIK46439.1 - 0.012 15.8 0.0 1.8 9.0 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat DUF3730 PF12530.8 KIK46439.1 - 0.06 12.9 0.0 0.19 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) HEAT_EZ PF13513.6 KIK46439.1 - 0.096 13.2 0.0 1 9.9 0.0 2.9 3 0 0 3 3 3 0 HEAT-like repeat Septin PF00735.18 KIK46440.1 - 1.7e-120 401.6 0.0 1.7e-120 401.6 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KIK46440.1 - 1e-07 32.0 0.1 3.9e-07 30.1 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KIK46440.1 - 0.00025 21.3 0.0 0.0054 17.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KIK46440.1 - 0.00045 20.2 0.7 0.00045 20.2 0.7 3.6 3 1 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 KIK46440.1 - 0.0011 19.1 2.8 0.84 9.7 0.0 3.2 3 0 0 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 KIK46440.1 - 0.005 16.4 4.8 0.045 13.3 0.1 3.6 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KIK46440.1 - 0.0071 16.7 0.1 0.041 14.3 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KIK46440.1 - 0.0082 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Ras PF00071.22 KIK46440.1 - 0.01 15.4 0.0 0.12 11.9 0.0 2.6 2 2 1 3 3 3 0 Ras family AIG1 PF04548.16 KIK46440.1 - 0.011 15.1 0.1 0.042 13.2 0.0 2.1 2 0 0 2 2 2 0 AIG1 family ABC_tran PF00005.27 KIK46440.1 - 0.039 14.5 10.4 0.044 14.3 1.5 2.9 1 1 1 2 2 2 0 ABC transporter Roc PF08477.13 KIK46440.1 - 0.12 12.6 0.0 0.42 10.9 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Exonuc_VII_L PF02601.15 KIK46440.1 - 0.75 9.3 4.9 1.3 8.5 4.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Strep_SA_rep PF06696.11 KIK46440.1 - 0.76 9.8 6.4 0.12 12.4 1.4 2.2 1 1 1 2 2 2 0 Streptococcal surface antigen repeat ATP_bind_1 PF03029.17 KIK46440.1 - 0.82 9.4 5.1 5.5 6.7 0.0 3.3 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 KIK46440.1 - 4.5 7.7 12.8 1e+03 0.0 12.8 2.4 1 1 0 1 1 1 0 AAA domain CN_hydrolase PF00795.22 KIK46442.1 - 4.4e-52 177.0 0.0 5e-52 176.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_hydro_56 PF01630.18 KIK46442.1 - 0.2 10.7 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Hyaluronidase MRP-S28 PF10213.9 KIK46443.1 - 1.5e-22 80.4 0.0 2.2e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF866 PF05907.13 KIK46444.1 - 9.4e-59 197.8 2.0 1.1e-58 197.6 2.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) zf-CHY PF05495.12 KIK46444.1 - 0.0097 16.4 0.6 0.016 15.7 0.6 1.3 1 0 0 1 1 1 1 CHY zinc finger Cytochrome_C7 PF14522.6 KIK46444.1 - 0.012 15.6 0.7 0.02 14.9 0.7 1.4 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c zf-C4pol PF14260.6 KIK46444.1 - 0.17 12.4 2.6 0.3 11.6 1.5 1.8 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zinc_ribbon_10 PF10058.9 KIK46444.1 - 0.17 11.6 2.0 8 6.3 2.0 2.4 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein PHD PF00628.29 KIK46444.1 - 0.26 11.2 4.0 0.4 10.6 1.0 2.2 2 0 0 2 2 2 0 PHD-finger Zn_Tnp_IS1595 PF12760.7 KIK46444.1 - 3.6 7.6 7.8 5.3 7.1 4.3 2.4 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Rubredoxin_2 PF18073.1 KIK46444.1 - 6.2 6.6 9.2 1.8 8.3 0.4 2.6 3 0 0 3 3 3 0 Rubredoxin metal binding domain Pkinase PF00069.25 KIK46445.1 - 4.1e-62 209.9 0.0 6.1e-62 209.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK46445.1 - 3.4e-41 141.2 0.0 5.5e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK46445.1 - 1.6e-13 50.7 0.0 1.2e-08 34.6 0.0 2.1 2 0 0 2 2 2 2 Kinase-like YrbL-PhoP_reg PF10707.9 KIK46445.1 - 0.002 17.7 0.0 0.0034 16.9 0.0 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 KIK46445.1 - 0.0032 17.4 0.0 2.3 8.1 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIK46445.1 - 0.012 14.4 0.1 0.024 13.4 0.1 1.3 1 1 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KIK46445.1 - 0.015 14.7 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IQ PF00612.27 KIK46446.1 - 0.028 14.2 3.3 0.028 14.2 3.3 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif Pkinase PF00069.25 KIK46447.1 - 4.7e-65 219.6 0.0 5.8e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK46447.1 - 1.1e-44 152.7 0.0 1.5e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK46447.1 - 8e-09 35.2 0.0 9.9e-06 25.1 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KIK46447.1 - 0.0023 17.3 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK46447.1 - 0.0031 16.3 0.0 0.0047 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KIK46447.1 - 0.033 13.2 0.0 0.057 12.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 KIK46447.1 - 0.056 12.9 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 KIK46447.1 - 0.11 12.3 0.0 0.4 10.5 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family CLTH PF10607.9 KIK46449.1 - 2.8e-34 118.1 0.1 3.6e-34 117.8 0.1 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KIK46449.1 - 9.7e-11 41.2 0.1 2.1e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 LisH Rrp15p PF07890.12 KIK46450.1 - 7.5e-25 87.8 7.4 9e-24 84.3 7.4 2.2 1 1 0 1 1 1 1 Rrp15p CDC45 PF02724.14 KIK46450.1 - 0.75 8.0 6.2 0.9 7.8 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DIL PF01843.19 KIK46451.1 - 3.6e-28 97.9 0.4 9e-28 96.6 0.4 1.7 1 0 0 1 1 1 1 DIL domain Ank_4 PF13637.6 KIK46451.1 - 2.8e-08 34.1 0.1 0.00013 22.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIK46451.1 - 5.9e-06 26.8 0.0 1.5e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIK46451.1 - 1e-05 25.7 0.0 0.12 12.7 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK46451.1 - 0.00013 22.1 0.2 0.081 13.5 0.1 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KIK46451.1 - 0.0073 16.7 1.1 4.9 7.8 0.2 3.6 3 0 0 3 3 3 1 Ankyrin repeat PP1c_bdg PF10488.9 KIK46451.1 - 0.11 12.0 2.0 0.46 9.9 1.8 1.9 2 0 0 2 2 2 0 Phosphatase-1 catalytic subunit binding region SnoaL PF07366.12 KIK46452.1 - 7.1e-07 29.1 0.1 0.00014 21.7 0.1 2.2 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KIK46452.1 - 0.00033 21.3 0.1 0.00081 20.0 0.1 1.6 1 1 0 1 1 1 1 SnoaL-like domain Rhomboid PF01694.22 KIK46453.1 - 1.5e-28 99.7 11.7 2.9e-28 98.8 11.7 1.5 1 0 0 1 1 1 1 Rhomboid family PetG PF02529.15 KIK46453.1 - 0.39 10.6 4.9 9 6.2 0.0 2.6 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 BaxI_1 PF12811.7 KIK46453.1 - 0.76 9.3 7.7 1.3 8.5 7.7 1.3 1 0 0 1 1 1 0 Bax inhibitor 1 like Cas1_AcylT PF07779.12 KIK46454.1 - 5.5e-142 474.0 24.3 8e-142 473.5 24.3 1.2 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 KIK46454.1 - 0.0029 17.4 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Form-deh_trans PF09163.11 KIK46454.1 - 0.078 12.8 0.3 0.078 12.8 0.3 2.5 3 0 0 3 3 3 0 Formate dehydrogenase N, transmembrane GPS PF01825.21 KIK46454.1 - 0.13 12.8 0.5 0.41 11.2 0.5 1.8 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif Cut8 PF08559.10 KIK46456.1 - 6.4e-11 42.3 0.2 4.9e-09 36.2 0.2 2.6 2 1 0 2 2 2 2 Cut8, nuclear proteasome tether protein TPR_19 PF14559.6 KIK46457.1 - 0.0074 16.8 0.0 1.3 9.6 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR_2 PF13041.6 KIK46457.1 - 0.0084 16.3 0.0 0.043 14.0 0.0 2.3 1 1 1 2 2 2 1 PPR repeat family HrpB1_HrpK PF09613.10 KIK46457.1 - 0.017 14.7 0.1 0.047 13.3 0.1 1.7 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) BTAD PF03704.17 KIK46457.1 - 0.064 13.7 0.9 0.28 11.6 0.2 2.2 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_14 PF13428.6 KIK46457.1 - 2.3 9.2 7.4 28 5.9 0.0 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat RINGv PF12906.7 KIK46460.1 - 1.4e-13 50.7 5.4 2.2e-13 50.1 5.4 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_4 PF14570.6 KIK46460.1 - 0.052 13.3 3.5 0.1 12.4 3.5 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 KIK46460.1 - 0.069 13.5 6.9 0.11 12.8 6.9 1.4 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.29 KIK46460.1 - 0.1 12.5 4.4 0.17 11.8 4.4 1.4 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 KIK46460.1 - 0.14 12.3 5.6 0.25 11.5 5.6 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain DUF983 PF06170.12 KIK46460.1 - 0.18 12.3 2.3 0.88 10.0 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF983) zf-C3HC4 PF00097.25 KIK46460.1 - 1.2 9.1 4.8 5.6 6.9 4.8 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Nucleoporin_N PF08801.11 KIK46461.1 - 9.8e-66 222.3 0.8 1.6e-65 221.6 0.8 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KIK46461.1 - 4.6e-36 124.8 0.0 3.3e-35 121.9 0.0 2.0 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal NAD_binding_6 PF08030.12 KIK46462.1 - 1.3e-24 87.0 0.0 2.8e-24 86.0 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KIK46462.1 - 1.4e-21 76.6 0.0 3.1e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KIK46462.1 - 3.5e-19 69.2 11.9 7.4e-19 68.1 11.9 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KIK46462.1 - 0.0076 16.9 0.0 0.047 14.3 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Coatomer_b_Cpla PF14806.6 KIK46462.1 - 0.081 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Ntox3 PF15536.6 KIK46462.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 3 CHAT PF12770.7 KIK46464.1 - 5.5e-35 121.2 0.0 1.8e-34 119.5 0.0 1.8 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIK46464.1 - 0.00081 19.2 9.1 1.1 9.3 0.0 6.3 6 1 0 6 6 6 1 Tetratricopeptide repeat Surp PF01805.20 KIK46464.1 - 0.0033 17.4 0.0 0.0069 16.4 0.0 1.5 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 KIK46468.1 - 1.3e-25 89.0 0.0 1.4e-12 47.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 KIK46468.1 - 4.4e-22 76.5 0.0 0.00016 21.2 0.0 5.8 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 KIK46468.1 - 1.7e-05 24.6 0.0 0.061 13.2 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nab6_mRNP_bdg PF10567.9 KIK46468.1 - 0.13 11.8 0.0 0.87 9.0 0.0 2.0 2 0 0 2 2 2 0 RNA-recognition motif WD40 PF00400.32 KIK46471.1 - 5.6e-56 185.2 16.1 1.1e-09 38.7 0.0 8.2 8 0 0 8 8 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK46471.1 - 6.8e-21 74.4 3.0 0.004 17.4 0.0 7.7 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 KIK46471.1 - 5.1e-13 49.6 3.1 4.5e-11 43.3 0.1 2.8 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Ge1_WD40 PF16529.5 KIK46471.1 - 3.6e-11 42.6 1.2 0.11 11.4 0.0 6.0 2 1 5 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_1 PF00515.28 KIK46471.1 - 9.1e-08 31.6 0.1 0.69 9.8 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK46471.1 - 8.2e-07 28.7 0.2 29 5.1 0.0 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK46471.1 - 0.0014 19.3 1.7 12 7.0 0.0 5.2 3 1 2 5 5 4 0 Tetratricopeptide repeat WD40_like PF17005.5 KIK46471.1 - 0.0015 17.9 0.0 2 7.6 0.0 4.1 5 0 0 5 5 5 1 WD40-like domain PD40 PF07676.12 KIK46471.1 - 0.0018 18.2 0.7 82 3.3 0.0 5.9 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Peptidase_S9_N PF02897.15 KIK46471.1 - 0.003 16.4 0.1 0.017 13.9 0.1 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Nup160 PF11715.8 KIK46471.1 - 0.0032 16.2 2.0 0.26 9.9 0.1 3.6 2 1 2 4 4 4 1 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIK46471.1 - 0.0066 15.8 0.6 2.2 7.5 0.0 3.8 1 1 4 5 5 5 1 Neuroblastoma-amplified sequence, N terminal TPR_19 PF14559.6 KIK46471.1 - 0.0082 16.6 0.7 7.4 7.2 0.0 3.9 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK46471.1 - 0.017 15.8 2.2 8.7 7.1 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIK46471.1 - 0.02 15.2 1.6 93 3.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK46471.1 - 0.069 13.4 0.4 7.5 6.9 0.0 3.3 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Frtz PF11768.8 KIK46471.1 - 0.082 11.2 0.0 36 2.5 0.0 3.5 2 1 2 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz TPR_11 PF13414.6 KIK46471.1 - 0.083 12.6 0.2 10 5.9 0.0 3.5 3 0 0 3 3 3 0 TPR repeat PQQ_2 PF13360.6 KIK46471.1 - 0.22 11.1 3.1 1 8.9 1.9 2.5 1 1 0 1 1 1 0 PQQ-like domain Mgr1 PF08602.10 KIK46472.1 - 0.8 8.5 3.5 1.2 7.8 3.5 1.3 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Presenilin PF01080.17 KIK46472.1 - 3.7 6.2 6.0 5.1 5.8 6.0 1.2 1 0 0 1 1 1 0 Presenilin Borrelia_P83 PF05262.11 KIK46472.1 - 5.8 5.3 15.7 7.8 4.9 15.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein FGF-BP1 PF06473.12 KIK46473.1 - 0.066 13.0 6.7 0.078 12.8 6.7 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) RNA_pol_Rpc4 PF05132.14 KIK46473.1 - 0.63 10.5 4.2 1.1 9.7 4.2 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Neur_chan_memb PF02932.16 KIK46473.1 - 1 9.3 3.6 1.3 9.0 3.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 KIK46473.1 - 3.4 6.3 10.7 4.7 5.9 10.7 1.1 1 0 0 1 1 1 0 Presenilin Haem_degrading PF03928.14 KIK46476.1 - 2.7e-33 114.6 0.0 3.1e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading MitMem_reg PF13012.6 KIK46478.1 - 3.8e-35 120.7 1.5 6.1e-35 120.0 1.5 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KIK46478.1 - 3.7e-30 104.3 0.0 7.2e-30 103.4 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Connexin PF00029.19 KIK46478.1 - 0.13 12.0 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 Connexin zf-CCHC PF00098.23 KIK46480.1 - 1.3e-37 126.2 43.9 4.1e-09 36.1 3.2 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.6 KIK46480.1 - 8.7e-07 28.8 25.3 0.045 13.7 0.8 5.1 3 2 2 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.6 KIK46480.1 - 9.2e-05 22.1 28.8 0.13 12.0 0.9 5.8 6 0 0 6 6 6 4 Zinc knuckle zf-CCHC_5 PF14787.6 KIK46480.1 - 0.006 16.3 21.4 0.069 12.9 0.8 5.0 4 1 1 5 5 5 2 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 KIK46480.1 - 0.99 9.3 31.5 0.76 9.7 3.8 4.8 4 1 0 4 4 4 0 Zinc knuckle COX4 PF02936.14 KIK46481.1 - 2.6e-39 134.4 0.0 3.1e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF2401 PF10287.9 KIK46482.1 - 0.09 12.4 0.1 0.095 12.3 0.1 1.0 1 0 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) ATP-synt_Eps PF04627.13 KIK46483.1 - 1.4e-20 73.0 3.9 1.9e-20 72.6 3.9 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Ras PF00071.22 KIK46484.1 - 2e-51 173.8 0.0 2.4e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK46484.1 - 4.1e-30 104.5 0.0 6.2e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK46484.1 - 1.7e-12 47.1 0.0 2.2e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIK46484.1 - 3.2e-05 24.0 0.0 5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIK46484.1 - 3.3e-05 23.5 0.0 0.00069 19.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIK46484.1 - 0.0013 18.6 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KIK46484.1 - 0.022 15.0 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIK46484.1 - 0.051 14.0 0.2 0.087 13.2 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.9 KIK46484.1 - 0.059 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 KIK46484.1 - 0.06 13.1 0.7 0.2 11.4 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 KIK46484.1 - 0.098 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 KIK46484.1 - 0.12 11.9 0.0 7.7 6.1 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KIK46484.1 - 0.14 12.7 0.0 0.46 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain DSPc PF00782.20 KIK46485.1 - 1.5e-26 92.8 0.0 1.6e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIK46485.1 - 0.0012 18.5 0.0 0.0013 18.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KIK46485.1 - 0.0017 18.6 0.0 0.0025 18.1 0.0 1.2 1 0 0 1 1 1 1 Rit1 DUSP-like domain Myotub-related PF06602.14 KIK46485.1 - 0.068 12.1 0.0 0.082 11.8 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DUF4062 PF13271.6 KIK46485.1 - 0.12 12.8 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) DEAD PF00270.29 KIK46486.1 - 1.9e-44 151.5 0.7 1.9e-44 151.5 0.7 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK46486.1 - 9.8e-33 112.8 0.4 2.1e-31 108.5 0.1 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK46486.1 - 7.9e-06 26.0 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KIK46486.1 - 0.00014 22.2 0.3 0.005 17.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIK46486.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK46486.1 - 0.018 15.3 0.5 0.12 12.6 0.5 2.3 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 KIK46486.1 - 0.035 14.0 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 Helicase Flavi_DEAD PF07652.14 KIK46486.1 - 0.076 13.0 0.1 0.37 10.7 0.1 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain p450 PF00067.22 KIK46487.1 - 1.1e-05 24.4 0.2 0.068 11.9 0.0 2.6 3 0 0 3 3 3 2 Cytochrome P450 COG6 PF06419.11 KIK46488.1 - 1e-156 522.8 0.0 1.3e-156 522.4 0.0 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DUF1664 PF07889.12 KIK46488.1 - 4.6 7.3 5.7 3 7.9 3.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) E1_dh PF00676.20 KIK46489.1 - 4.9e-113 377.0 0.0 5.8e-113 376.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KIK46489.1 - 0.00048 19.4 0.1 0.001 18.3 0.0 1.5 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KIK46489.1 - 0.0052 16.6 2.1 0.0058 16.4 0.7 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PMT PF02366.18 KIK46490.1 - 2.1e-80 269.9 19.7 3.8e-80 269.0 19.7 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KIK46490.1 - 4.4e-58 196.2 13.6 4.4e-58 196.2 13.6 2.1 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KIK46490.1 - 5e-27 95.0 1.1 8e-27 94.3 1.1 1.2 1 0 0 1 1 1 1 MIR domain Fibrillarin PF01269.17 KIK46491.1 - 3.2e-107 356.8 0.0 4e-107 356.5 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KIK46491.1 - 1.6e-05 24.7 0.0 2.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KIK46491.1 - 0.0011 18.8 0.1 0.0017 18.1 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KIK46491.1 - 0.035 14.2 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF2423 PF10338.9 KIK46491.1 - 0.064 13.5 0.0 2.4 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) Methyltr_RsmB-F PF01189.17 KIK46491.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.5 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F TehB PF03848.14 KIK46491.1 - 0.16 11.3 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB GcnA_N PF18229.1 KIK46491.1 - 0.23 11.5 0.6 1.3 9.1 0.1 2.4 3 0 0 3 3 3 0 N-acetyl-beta-D-glucosaminidase N-terminal domain MFS_1 PF07690.16 KIK46493.1 - 4e-22 78.6 51.5 2.4e-14 53.0 26.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KIK46495.1 - 1.1e-17 64.1 45.3 2.1e-17 63.1 42.7 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF5478 PF17572.2 KIK46495.1 - 0.055 13.6 0.3 0.13 12.4 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5478) DUF3270 PF11674.8 KIK46495.1 - 2.5 8.3 6.5 0.2 11.9 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) MFS_1 PF07690.16 KIK46496.1 - 7.5e-21 74.4 79.7 1.6e-17 63.5 37.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C3HC4_3 PF13920.6 KIK46497.1 - 4.1e-05 23.3 7.0 4.1e-05 23.3 7.0 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-H2C2_5 PF13909.6 KIK46497.1 - 0.00087 19.0 0.0 0.0033 17.1 0.0 2.0 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIK46497.1 - 0.15 12.6 14.9 0.78 10.3 1.6 4.8 5 0 0 5 5 5 0 Zinc finger, C2H2 type Prok-RING_4 PF14447.6 KIK46497.1 - 8.8 6.3 14.1 3 7.8 5.9 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FlaC_arch PF05377.11 KIK46498.1 - 8.3 6.9 5.8 47 4.5 0.0 3.7 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) UCH PF00443.29 KIK46499.1 - 1.1e-41 143.1 0.0 1.8e-41 142.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIK46499.1 - 1.1e-07 31.8 0.0 5e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase BDV_P10 PF06515.11 KIK46499.1 - 0.41 10.7 2.1 2.3 8.3 2.1 2.3 1 0 0 1 1 1 0 Borna disease virus P10 protein Vpu PF00558.19 KIK46500.1 - 0.22 11.3 0.6 0.48 10.2 0.6 1.5 1 0 0 1 1 1 0 Vpu protein GPI2 PF06432.11 KIK46500.1 - 5.9 6.2 10.7 1.7 8.0 2.0 2.1 1 1 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase ADH_zinc_N PF00107.26 KIK46501.1 - 2.7e-21 75.9 0.6 5.4e-21 74.9 0.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK46501.1 - 7e-11 43.3 0.2 1.6e-10 42.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK46501.1 - 1.8e-06 27.8 0.0 1.3e-05 25.0 0.0 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KIK46501.1 - 0.056 12.9 1.2 0.1 12.1 0.9 1.6 1 1 0 1 1 1 0 short chain dehydrogenase IBR PF01485.21 KIK46502.1 - 2.3e-15 56.5 37.2 5.9e-08 32.8 6.9 3.2 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 KIK46502.1 - 0.008 16.2 5.6 0.008 16.2 5.6 4.1 3 3 1 4 4 4 1 RING-type zinc-finger IBR PF01485.21 KIK46503.1 - 3.5e-14 52.8 46.7 1.9e-07 31.2 8.2 4.3 4 0 0 4 4 4 4 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KIK46503.1 - 0.00029 20.6 2.4 0.00029 20.6 2.4 4.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK46503.1 - 0.011 15.8 5.2 0.011 15.8 5.2 3.7 3 1 0 3 3 3 0 RING-type zinc-finger SNURF PF07192.11 KIK46503.1 - 0.028 14.3 1.7 0.25 11.2 0.0 2.8 3 0 0 3 3 3 0 SNURF/RPN4 protein zf-RING_11 PF17123.5 KIK46503.1 - 0.46 10.3 8.9 0.056 13.2 2.7 2.8 2 0 0 2 2 2 0 RING-like zinc finger IBR PF01485.21 KIK46504.1 - 6.6e-13 48.7 28.2 7.2e-08 32.5 12.8 4.1 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KIK46504.1 - 0.028 14.8 6.0 0.028 14.8 6.0 4.6 4 1 0 4 4 4 0 Ring finger domain Ribosomal_L37 PF08561.10 KIK46507.1 - 3.1e-18 66.4 7.4 1.1e-15 58.2 0.2 2.3 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 Choline_transpo PF04515.12 KIK46509.1 - 3.5e-48 164.5 6.1 3.5e-48 164.5 6.1 2.4 2 1 0 2 2 2 1 Plasma-membrane choline transporter SUR7 PF06687.12 KIK46509.1 - 4.8 6.7 11.3 0.86 9.2 5.8 2.3 2 0 0 2 2 2 0 SUR7/PalI family TPP_enzyme_N PF02776.18 KIK46518.1 - 1.7e-55 187.3 0.0 3.5e-55 186.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KIK46518.1 - 2.4e-46 157.3 0.6 4.1e-45 153.3 0.3 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KIK46518.1 - 5.9e-40 136.2 0.9 1.7e-39 134.7 0.3 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain AAA_5 PF07728.14 KIK46520.1 - 6.7e-05 22.9 0.0 9.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KIK46520.1 - 0.0003 21.2 0.0 0.0005 20.5 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK46520.1 - 0.0012 19.3 0.0 0.05 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KIK46520.1 - 0.003 16.7 0.0 0.0053 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 KIK46520.1 - 0.028 14.2 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KIK46520.1 - 0.056 13.6 0.1 0.57 10.3 0.1 2.4 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KIK46520.1 - 0.058 13.1 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 KIK46520.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FAA_hydrolase PF01557.18 KIK46521.1 - 3.4e-56 190.3 0.0 4.2e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.17 KIK46521.1 - 0.0052 16.6 0.1 0.074 12.9 0.0 2.2 2 0 0 2 2 2 1 KH domain SAPS PF04499.15 KIK46522.1 - 1.1e-127 426.8 0.0 1.4e-127 426.5 0.0 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Adap_comp_sub PF00928.21 KIK46522.1 - 1.2e-06 28.1 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Pap_E4 PF02711.14 KIK46522.1 - 1.5 9.8 4.5 19 6.3 0.8 3.2 3 0 0 3 3 3 0 E4 protein Adap_comp_sub PF00928.21 KIK46523.1 - 4.1e-15 55.9 0.0 6.2e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KIK46523.1 - 2.2e-08 34.1 2.4 3.3e-08 33.6 2.4 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF5618 PF18498.1 KIK46523.1 - 0.046 13.9 0.1 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5618) Lipase_GDSL_2 PF13472.6 KIK46526.1 - 4.7e-10 40.2 0.2 6.5e-10 39.7 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIK46526.1 - 1.6e-07 31.5 0.1 2e-07 31.2 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase zf-MYND PF01753.18 KIK46527.1 - 8.1e-11 41.8 19.3 1.4e-10 41.1 19.3 1.4 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.13 KIK46527.1 - 1.6 6.5 4.9 2.1 6.1 4.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-C6H2 PF15801.5 KIK46527.1 - 1.7 9.0 18.7 4 7.8 17.3 2.3 2 1 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding DUF4432 PF14486.6 KIK46530.1 - 0.023 13.5 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) TMEM173 PF15009.6 KIK46530.1 - 0.036 13.2 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 173 RhoGEF PF00621.20 KIK46532.1 - 3.7e-07 30.5 0.0 4e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 RhoGEF domain BBE PF08031.12 KIK46532.1 - 6.1e-07 29.4 0.1 1.3e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 KIK46532.1 - 0.084 12.6 0.0 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Plavaka PF18759.1 KIK46533.1 - 1.5e-28 100.0 0.9 2.2e-28 99.4 0.0 1.7 2 0 0 2 2 2 1 Plavaka transposase NYN PF01936.18 KIK46534.1 - 0.16 12.5 0.0 0.22 12.0 0.0 1.1 1 0 0 1 1 1 0 NYN domain PMEI PF04043.15 KIK46535.1 - 0.036 14.4 0.1 0.24 11.8 0.0 2.0 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor adh_short PF00106.25 KIK46537.1 - 2.7e-24 85.7 0.9 2.1e-22 79.6 0.9 2.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK46537.1 - 9.4e-24 84.3 0.1 3.4e-12 46.4 0.0 3.9 3 1 1 4 4 4 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK46537.1 - 1.7e-06 28.1 0.1 3.3e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_Gly3P_dh_N PF01210.23 KIK46537.1 - 0.027 14.5 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Epimerase PF01370.21 KIK46537.1 - 0.11 12.0 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KIK46537.1 - 0.2 11.5 0.2 0.32 10.9 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PAP1 PF08601.10 KIK46540.1 - 0.43 10.3 4.4 0.55 9.9 4.4 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 PAP_assoc PF03828.19 KIK46541.1 - 1.7e-17 63.4 0.2 6.1e-17 61.6 0.2 2.1 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KIK46541.1 - 1.4e-08 34.9 0.0 3.6e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KIK46541.1 - 0.059 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase PLAC9 PF15205.6 KIK46543.1 - 0.12 12.8 0.2 0.16 12.4 0.2 1.4 1 0 0 1 1 1 0 Placenta-specific protein 9 CHAT PF12770.7 KIK46544.1 - 2e-21 76.7 0.0 2.5e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 CHAT domain Surp PF01805.20 KIK46544.1 - 0.0024 17.8 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 Surp module DUF3504 PF12012.8 KIK46546.1 - 0.075 12.9 1.1 0.27 11.1 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3504) Plavaka PF18759.1 KIK46548.1 - 6e-30 104.6 0.2 2.2e-28 99.5 0.0 2.5 2 1 0 2 2 2 2 Plavaka transposase UPF0223 PF05256.12 KIK46548.1 - 0.027 14.8 0.2 0.089 13.1 0.2 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0223) Clathrin PF00637.20 KIK46552.1 - 0.0014 18.5 0.1 0.0026 17.6 0.1 1.4 1 1 0 1 1 1 1 Region in Clathrin and VPS WD40 PF00400.32 KIK46553.1 - 1.8e-21 76.0 2.4 6.9e-08 33.0 0.1 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat WD40_like PF17005.5 KIK46553.1 - 0.0055 16.1 0.0 0.023 14.1 0.0 1.8 2 0 0 2 2 2 1 WD40-like domain ANAPC4_WD40 PF12894.7 KIK46553.1 - 0.015 15.6 0.0 4 7.8 0.0 2.5 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WW PF00397.26 KIK46554.1 - 0.0034 17.4 0.7 0.0099 15.9 0.7 1.8 1 0 0 1 1 1 1 WW domain Thaumatin PF00314.17 KIK46556.1 - 2.4e-12 47.0 12.9 3e-12 46.7 12.9 1.2 1 0 0 1 1 1 1 Thaumatin family RRM_1 PF00076.22 KIK46557.1 - 3.6e-12 45.9 0.0 5.2e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KIK46557.1 - 3.4e-06 27.5 0.3 8.6e-06 26.2 0.3 1.6 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Dioxygenase_C PF00775.21 KIK46558.1 - 3.5e-43 147.1 0.0 4.9e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KIK46558.1 - 1.9e-29 101.3 0.0 3.5e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KIK46558.1 - 0.0025 18.1 0.2 0.057 13.7 0.2 3.0 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain AAA PF00004.29 KIK46559.1 - 1.1e-17 64.6 0.0 2.2e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK46559.1 - 2.6e-05 24.7 0.3 7.2e-05 23.2 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK46559.1 - 5.7e-05 23.4 0.9 0.0015 18.8 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KIK46559.1 - 0.0014 18.7 0.4 0.0092 16.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KIK46559.1 - 0.0029 17.8 0.0 0.012 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIK46559.1 - 0.0055 16.4 0.1 0.014 15.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK46559.1 - 0.0069 16.2 0.2 0.016 15.0 0.1 1.6 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 KIK46559.1 - 0.025 13.8 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_19 PF13245.6 KIK46559.1 - 0.036 14.4 0.0 0.08 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KIK46559.1 - 0.038 13.7 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KIK46559.1 - 0.052 14.1 0.0 0.18 12.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 KIK46559.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KIK46559.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF805 PF05656.14 KIK46563.1 - 0.23 11.9 0.1 0.23 11.9 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF805) DUF2855 PF11017.8 KIK46565.1 - 4.2e-97 325.9 0.0 4.8e-97 325.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) DUF4976 PF16347.5 KIK46566.1 - 0.19 12.0 11.0 1.6 9.1 1.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4976) Sec23_trunk PF04811.15 KIK46567.1 - 2.4e-41 141.9 0.0 3.5e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KIK46567.1 - 3.3e-21 75.0 0.6 7.2e-21 74.0 0.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KIK46567.1 - 8.1e-18 65.0 0.0 1.9e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KIK46567.1 - 4.3e-14 52.3 3.4 1.2e-13 50.8 3.4 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KIK46567.1 - 0.0003 20.6 0.0 0.0006 19.7 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat MFS_1 PF07690.16 KIK46572.1 - 2.7e-37 128.5 53.7 2.7e-37 128.5 53.7 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK46572.1 - 1.6e-19 69.8 22.8 3.6e-19 68.6 22.8 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIK46572.1 - 7e-10 38.4 12.5 7e-10 38.4 12.5 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KIK46572.1 - 0.0023 16.3 5.6 0.0023 16.3 5.6 2.4 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF917 PF06032.12 KIK46573.1 - 2.2e-113 378.7 0.1 3.4e-113 378.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 KIK46573.1 - 2.5e-26 92.5 4.0 7.9e-25 87.6 0.5 3.1 3 1 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 KIK46573.1 - 1.2e-25 90.3 5.8 4.5e-23 81.9 1.5 4.0 3 1 1 4 4 4 2 Hydantoinase/oxoprolinase MutL PF13941.6 KIK46573.1 - 1.1e-07 30.9 4.7 0.00021 20.0 0.3 2.7 3 0 0 3 3 3 2 MutL protein BcrAD_BadFG PF01869.20 KIK46573.1 - 0.00077 19.0 3.7 0.0031 17.1 0.1 2.6 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.11 KIK46573.1 - 0.0055 16.0 0.3 0.67 9.1 0.1 2.6 2 0 0 2 2 2 2 StbA protein ROK PF00480.20 KIK46573.1 - 0.035 13.6 0.1 0.093 12.2 0.1 1.7 1 0 0 1 1 1 0 ROK family Mcp5_PH PF12814.7 KIK46574.1 - 2.5e-46 156.8 0.1 5.7e-46 155.6 0.1 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KIK46574.1 - 1.1e-05 25.9 0.0 2.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 PH domain RCC1 PF00415.18 KIK46574.1 - 0.11 13.1 0.1 0.33 11.6 0.1 1.8 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat Spc7 PF08317.11 KIK46574.1 - 0.16 10.8 32.9 0.0093 14.9 14.0 3.5 3 0 0 3 3 3 0 Spc7 kinetochore protein ATG16 PF08614.11 KIK46574.1 - 0.18 12.0 41.1 0.035 14.3 17.9 4.4 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 KIK46574.1 - 0.51 9.6 25.9 0.37 10.1 5.6 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) DSPc PF00782.20 KIK46575.1 - 9.3e-27 93.5 0.0 1.3e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIK46575.1 - 0.00011 21.8 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DZR PF12773.7 KIK46575.1 - 0.092 12.8 4.3 0.77 9.8 2.5 2.4 2 0 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KIK46575.1 - 0.26 11.3 4.5 5.1 7.2 2.0 2.3 2 0 0 2 2 2 0 zinc-ribbons P33MONOX PF15302.6 KIK46576.1 - 0.054 13.2 3.5 0.073 12.8 3.5 1.2 1 0 0 1 1 1 0 P33 mono-oxygenase DnaJ PF00226.31 KIK46577.1 - 9.5e-18 64.1 0.1 4.1e-17 62.0 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain TOBE_2 PF08402.10 KIK46578.1 - 0.092 12.9 0.0 0.29 11.3 0.0 1.8 1 1 1 2 2 2 0 TOBE domain C2 PF00168.30 KIK46579.1 - 1.9e-10 40.9 0.0 0.0011 19.2 0.0 2.5 2 0 0 2 2 2 2 C2 domain AAA_16 PF13191.6 KIK46579.1 - 1.8e-05 25.2 0.0 9.4e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KIK46579.1 - 3.7e-05 23.9 0.0 0.00074 19.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KIK46579.1 - 0.00012 22.0 0.0 0.00028 20.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KIK46579.1 - 0.00013 22.2 0.1 0.0029 17.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KIK46579.1 - 0.001 18.3 0.0 0.0028 16.9 0.0 1.8 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 KIK46579.1 - 0.0026 18.3 0.0 0.0077 16.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KIK46579.1 - 0.0035 17.0 0.2 0.026 14.3 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 KIK46579.1 - 0.0071 16.8 0.0 0.019 15.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_PrkA PF08298.11 KIK46579.1 - 0.019 13.9 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain RuvB_N PF05496.12 KIK46579.1 - 0.022 14.5 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 KIK46579.1 - 0.031 14.2 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KIK46579.1 - 0.056 13.5 0.1 0.31 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KIK46579.1 - 0.09 12.5 0.0 0.29 10.8 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KIK46579.1 - 0.1 13.2 0.0 0.44 11.1 0.0 2.2 2 1 0 2 2 1 0 AAA domain AAA_5 PF07728.14 KIK46579.1 - 0.1 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KIK46579.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain Cytidylate_kin PF02224.18 KIK46579.1 - 0.14 11.9 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase AAA_7 PF12775.7 KIK46579.1 - 0.15 11.6 0.1 0.59 9.6 0.0 2.0 3 0 0 3 3 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 KIK46579.1 - 0.16 12.5 0.5 0.82 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta2 PF13177.6 KIK46579.1 - 0.16 11.8 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase III, delta subunit RNA_helicase PF00910.22 KIK46579.1 - 0.16 12.3 0.0 0.47 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Ribosomal_L33 PF00471.20 KIK46580.1 - 6.1e-08 33.0 0.0 7.7e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 Nudix_N PF12535.8 KIK46580.1 - 0.087 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal Metallophos_2 PF12850.7 KIK46581.1 - 7.1e-20 71.8 0.1 9.7e-20 71.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KIK46581.1 - 1.2e-06 29.2 0.4 0.009 16.5 0.1 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase WD40 PF00400.32 KIK46585.1 - 8.4e-55 181.5 20.2 1.7e-07 31.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 KIK46585.1 - 8.1e-29 99.7 3.7 1.3e-28 99.1 3.7 1.3 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 KIK46585.1 - 2.4e-19 69.4 0.9 0.00023 21.4 0.0 6.5 2 2 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK46585.1 - 2.2e-10 40.3 0.0 0.05 12.9 0.0 5.0 5 1 1 6 6 6 3 WD40-like domain Ge1_WD40 PF16529.5 KIK46585.1 - 6.5e-08 31.9 1.4 1.2 8.0 0.0 5.5 1 1 5 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK46585.1 - 0.00029 20.7 0.6 13 5.9 0.0 5.9 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KIK46585.1 - 0.00048 20.1 0.0 9.5 6.0 0.0 3.7 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KIK46585.1 - 0.002 17.5 0.2 11 5.3 0.0 3.8 2 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK46585.1 - 0.0043 15.8 0.4 2 7.0 0.2 4.0 3 1 0 3 3 3 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KIK46585.1 - 0.0067 15.0 0.3 0.1 11.1 0.0 2.5 2 1 0 2 2 2 1 Cytochrome D1 heme domain Spc7 PF08317.11 KIK46585.1 - 0.11 11.3 0.5 0.17 10.7 0.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein VID27 PF08553.10 KIK46585.1 - 0.19 10.8 0.1 11 4.9 0.0 2.8 2 1 1 3 3 3 0 VID27 C-terminal WD40-like domain WD40 PF00400.32 KIK46586.1 - 1.1e-45 152.6 8.8 2.5e-08 34.4 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK46586.1 - 2.1e-14 53.6 0.2 0.0019 18.4 0.0 5.8 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK46586.1 - 2.3e-06 26.8 0.2 2.9 6.8 0.0 4.8 2 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK46586.1 - 0.00014 20.7 2.7 0.21 10.2 0.1 3.8 3 1 1 5 5 5 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK46586.1 - 0.002 17.5 0.0 2.3 7.5 0.0 3.7 4 0 0 4 4 4 1 WD40-like domain PALB2_WD40 PF16756.5 KIK46586.1 - 0.0029 16.6 0.1 0.008 15.1 0.1 1.8 2 0 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain NHL PF01436.21 KIK46586.1 - 0.1 12.7 0.6 1.3 9.2 0.0 2.8 3 0 0 3 3 3 0 NHL repeat Asp PF00026.23 KIK46587.1 - 3.2e-65 220.6 0.1 3.9e-65 220.4 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK46587.1 - 5e-05 23.6 1.9 0.0023 18.2 0.1 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal CNH PF00780.22 KIK46587.1 - 0.094 12.3 0.0 0.27 10.8 0.0 1.7 1 1 0 1 1 1 0 CNH domain Asp PF00026.23 KIK46588.1 - 5.1e-62 210.1 7.0 8e-62 209.5 7.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK46588.1 - 0.0033 17.7 3.4 0.081 13.1 0.1 3.0 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KIK46588.1 - 0.043 13.6 0.4 0.29 10.9 0.1 2.3 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Sigma54_DBD PF04552.13 KIK46589.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 Sigma-54, DNA binding domain RRN3 PF05327.11 KIK46589.1 - 0.15 10.6 0.2 0.13 10.8 0.2 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HCNGP PF07818.13 KIK46590.1 - 1.2e-27 96.4 0.1 2.7e-27 95.3 0.1 1.6 1 0 0 1 1 1 1 HCNGP-like protein Peptidase_C13 PF01650.18 KIK46592.1 - 1.5e-43 149.2 0.3 1.9e-43 148.9 0.3 1.1 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 KIK46592.1 - 0.12 12.6 0.1 0.45 10.8 0.0 1.9 2 0 0 2 2 2 0 Mid domain of argonaute adh_short PF00106.25 KIK46593.1 - 2.3e-25 89.2 0.0 2.8e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK46593.1 - 2.1e-20 73.3 0.0 2.5e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK46593.1 - 1.2e-05 25.3 0.1 1.9e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KIK46593.1 - 0.00018 21.4 0.1 0.00028 20.9 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIK46593.1 - 0.04 13.4 0.1 0.063 12.7 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family BrnT_toxin PF04365.13 KIK46593.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system Asp PF00026.23 KIK46594.1 - 0.065 12.7 0.0 0.08 12.4 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic aspartyl protease Melibiase_2 PF16499.5 KIK46595.1 - 2.3e-53 181.2 2.0 3.6e-53 180.6 2.0 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KIK46595.1 - 2.5e-15 56.3 0.1 9.7e-15 54.4 0.0 1.9 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KIK46595.1 - 6.4e-06 25.4 0.0 9.8e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 Melibiase tRNA-synt_2 PF00152.20 KIK46596.1 - 1.2e-84 284.1 0.0 1.4e-84 283.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIK46596.1 - 7.1e-08 32.3 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain LSM PF01423.22 KIK46597.1 - 2.3e-19 68.8 0.8 3e-19 68.5 0.8 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIK46597.1 - 0.0023 18.1 0.1 0.0029 17.7 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain BPL_C PF02237.17 KIK46597.1 - 0.02 14.7 0.2 0.038 13.9 0.2 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Gemin7 PF11095.8 KIK46597.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Melibiase_2 PF16499.5 KIK46598.1 - 1.2e-54 185.4 7.1 2.4e-54 184.5 7.1 1.5 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KIK46598.1 - 1.6e-16 60.1 0.1 4.2e-15 55.6 0.0 2.3 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Hist_deacetyl PF00850.19 KIK46599.1 - 4.4e-58 197.2 0.0 5.6e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain R3H PF01424.22 KIK46599.1 - 0.042 13.8 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 R3H domain TAL_FSA PF00923.19 KIK46600.1 - 6.1e-39 134.1 0.4 7.7e-39 133.8 0.4 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Alpha-L-AF_C PF06964.12 KIK46602.1 - 1.5e-40 139.0 0.2 2.7e-40 138.2 0.2 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_6 PF03422.15 KIK46602.1 - 0.0023 18.2 1.3 0.0061 16.8 1.3 1.7 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) DUF1343 PF07075.11 KIK46602.1 - 0.097 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1343) MRP-L27 PF09809.9 KIK46603.1 - 3.3e-08 33.4 0.2 4e-08 33.1 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Ribo_biogen_C PF04034.13 KIK46604.1 - 3.7e-51 172.1 0.0 5.1e-51 171.7 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KIK46604.1 - 9.7e-15 54.1 0.0 1.5e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Peptidase_S11 PF00768.20 KIK46604.1 - 0.082 12.3 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Pkinase PF00069.25 KIK46605.1 - 1.6e-67 227.6 0.0 1.9e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK46605.1 - 2.8e-31 108.8 0.0 5e-31 107.9 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK46605.1 - 0.00025 20.4 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK46605.1 - 0.00051 19.5 0.1 0.00084 18.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK46605.1 - 0.0051 16.8 1.5 0.84 9.5 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK46605.1 - 0.015 14.3 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KIK46605.1 - 0.13 11.0 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Torus PF16131.5 KIK46606.1 - 6.1e-09 36.6 5.6 0.00032 21.4 0.3 2.4 1 1 1 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 KIK46606.1 - 7.9e-09 35.1 7.7 7.9e-05 22.4 0.7 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 KIK46606.1 - 3.2e-06 26.9 5.9 0.00013 21.7 1.0 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIK46606.1 - 9e-06 25.6 12.7 9.7e-05 22.3 1.7 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 KIK46606.1 - 0.00045 20.4 0.5 0.00085 19.5 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KIK46606.1 - 5.6 7.6 11.8 0.21 12.1 2.3 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger WEMBL PF05701.11 KIK46608.1 - 0.0047 15.7 9.6 0.0069 15.1 8.2 1.8 2 0 0 2 2 2 1 Weak chloroplast movement under blue light DivIC PF04977.15 KIK46608.1 - 0.012 15.4 1.7 0.012 15.4 1.7 2.6 2 0 0 2 2 2 0 Septum formation initiator Spc7 PF08317.11 KIK46608.1 - 0.017 14.0 9.4 0.17 10.8 9.5 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein PEARLI-4 PF05278.12 KIK46608.1 - 0.029 13.9 0.4 0.058 13.0 0.4 1.4 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF4201 PF13870.6 KIK46608.1 - 0.085 12.6 7.4 0.23 11.1 7.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Kre28 PF17097.5 KIK46608.1 - 0.094 11.7 5.8 0.49 9.3 5.8 2.2 1 1 0 1 1 1 0 Spindle pole body component ApoLp-III PF07464.11 KIK46608.1 - 0.18 11.9 4.9 0.67 10.0 0.4 2.4 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) HIP1_clath_bdg PF16515.5 KIK46608.1 - 0.59 10.8 7.7 1.4 9.5 0.6 2.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MerR-DNA-bind PF09278.11 KIK46608.1 - 0.61 10.7 10.4 1.5 9.4 0.5 3.7 2 1 1 3 3 3 0 MerR, DNA binding COG2 PF06148.11 KIK46608.1 - 2.6 8.1 6.0 1.8 8.6 1.2 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_TATA_bd PF12325.8 KIK46608.1 - 2.8 8.2 10.1 3.9 7.7 1.2 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Nup54 PF13874.6 KIK46608.1 - 5.5 7.1 8.9 12 6.0 8.5 1.7 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Atg14 PF10186.9 KIK46608.1 - 5.7 5.9 9.6 80 2.2 9.6 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 p450 PF00067.22 KIK46609.1 - 2.7e-59 201.1 0.0 3.1e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transket_pyr PF02779.24 KIK46610.1 - 9.9e-67 224.0 0.0 1.6e-66 223.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KIK46610.1 - 1.9e-59 201.1 0.0 2.7e-59 200.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KIK46610.1 - 1.7e-51 173.9 0.0 2.9e-51 173.1 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KIK46610.1 - 1.5e-18 66.1 1.4 3e-18 65.1 1.4 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Kinesin PF00225.23 KIK46611.1 - 1.5e-92 310.1 0.0 2.2e-92 309.6 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KIK46611.1 - 5.8e-21 75.0 0.0 1.2e-20 74.0 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding TPR_2 PF07719.17 KIK46611.1 - 0.0031 17.5 0.1 0.0065 16.5 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIK46611.1 - 0.0084 16.2 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIK46611.1 - 0.0085 16.4 0.1 0.019 15.2 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK46611.1 - 0.017 15.1 0.0 0.057 13.5 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK46611.1 - 0.03 15.1 0.0 0.092 13.6 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK46611.1 - 0.087 13.5 0.0 0.19 12.4 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat FAM76 PF16046.5 KIK46611.1 - 0.14 11.5 0.7 0.27 10.5 0.7 1.4 1 0 0 1 1 1 0 FAM76 protein Exonuc_VII_L PF02601.15 KIK46611.1 - 0.24 10.9 2.2 0.49 9.9 2.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Arm-DNA-bind_5 PF17293.2 KIK46611.1 - 1.8 9.0 4.7 2.3 8.7 2.6 2.2 2 0 0 2 2 2 0 Arm DNA-binding domain MPS2 PF17060.5 KIK46611.1 - 2.1 7.5 5.4 3.5 6.8 5.4 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 ATG16 PF08614.11 KIK46613.1 - 0.0005 20.4 16.4 0.0005 20.4 16.4 5.8 3 1 2 6 6 6 4 Autophagy protein 16 (ATG16) BST2 PF16716.5 KIK46613.1 - 0.0061 17.1 0.6 0.0061 17.1 0.6 7.1 4 1 1 6 6 6 2 Bone marrow stromal antigen 2 BLOC1_2 PF10046.9 KIK46613.1 - 0.017 15.4 0.4 0.017 15.4 0.4 6.3 5 1 0 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 KIK46613.1 - 0.035 14.7 0.3 0.035 14.7 0.3 7.6 6 1 1 8 8 8 0 SlyX FPP PF05911.11 KIK46613.1 - 0.052 11.7 51.0 0.012 13.8 17.7 4.1 2 1 1 4 4 4 0 Filament-like plant protein, long coiled-coil DivIC PF04977.15 KIK46613.1 - 0.077 12.8 0.2 0.077 12.8 0.2 7.5 7 2 1 8 8 8 0 Septum formation initiator APG6_N PF17675.1 KIK46613.1 - 0.27 11.8 74.6 0.074 13.6 7.0 6.8 3 1 3 7 7 7 0 Apg6 coiled-coil region FlaC_arch PF05377.11 KIK46613.1 - 0.34 11.3 18.3 6.8 7.2 0.1 7.5 8 1 1 9 9 9 0 Flagella accessory protein C (FlaC) GAS PF13851.6 KIK46613.1 - 1.5 8.2 57.1 0.13 11.6 0.7 6.8 4 1 3 7 7 7 0 Growth-arrest specific micro-tubule binding Bap31_Bap29_C PF18035.1 KIK46613.1 - 1.6 8.8 12.4 1.1 9.3 0.1 4.3 3 1 0 3 3 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Fez1 PF06818.15 KIK46613.1 - 4.8 7.6 57.4 0.19 12.2 1.1 5.2 3 1 1 4 4 3 0 Fez1 DUF948 PF06103.11 KIK46613.1 - 8.7 6.7 23.5 0.089 13.1 1.1 4.9 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) BCDHK_Adom3 PF10436.9 KIK46615.1 - 1.2e-67 226.8 0.0 1.8e-67 226.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KIK46615.1 - 1.2e-13 51.5 0.0 2.8e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KIK46615.1 - 0.014 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3719 PF12516.8 KIK46615.1 - 0.077 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) Csc2 PF18320.1 KIK46616.1 - 0.15 11.0 0.0 0.19 10.7 0.0 1.0 1 0 0 1 1 1 0 Csc2 Crispr Plavaka PF18759.1 KIK46619.1 - 5.2e-23 81.8 4.5 8.8e-12 44.9 0.4 3.2 1 1 2 3 3 3 3 Plavaka transposase ALMT PF11744.8 KIK46619.1 - 0.2 10.5 0.1 0.3 9.9 0.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RNA_pol_Rpb1_5 PF04998.17 KIK46621.1 - 5.1e-85 285.1 0.0 8.8e-85 284.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KIK46621.1 - 9.6e-64 214.6 0.0 1.8e-63 213.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KIK46621.1 - 2.6e-37 128.2 0.0 5.5e-37 127.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KIK46621.1 - 2.7e-31 109.1 0.3 2.8e-24 86.0 0.0 3.5 3 1 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KIK46621.1 - 1.1e-19 70.3 0.0 2.8e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RRM_1 PF00076.22 KIK46625.1 - 2.4e-18 65.7 1.8 2.5e-18 65.7 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIK46625.1 - 1.3e-08 34.5 0.0 1.5e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIK46625.1 - 0.013 15.5 0.2 0.021 14.8 0.2 1.4 1 1 0 1 1 1 0 RNA binding motif RRM_8 PF11835.8 KIK46625.1 - 0.046 13.9 0.0 0.097 12.9 0.0 1.5 1 1 1 2 2 2 0 RRM-like domain RRM_occluded PF16842.5 KIK46625.1 - 0.085 12.7 0.2 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif CxC6 PF18721.1 KIK46628.1 - 0.0011 19.2 0.2 0.0011 19.2 0.2 1.1 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases DEAD PF00270.29 KIK46629.1 - 3.4e-43 147.4 0.1 5.7e-43 146.7 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK46629.1 - 2.8e-31 108.1 0.1 1.1e-30 106.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK46629.1 - 0.0004 20.4 0.0 0.00099 19.1 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KIK46629.1 - 0.00045 20.6 0.1 0.021 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIK46629.1 - 0.026 14.2 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK46629.1 - 0.077 13.3 0.6 0.44 10.8 0.6 2.1 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 KIK46629.1 - 0.15 11.5 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF3449 PF11931.8 KIK46630.1 - 3e-74 248.8 1.4 6.2e-73 244.5 0.1 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KIK46630.1 - 5.4e-25 87.7 5.0 7e-25 87.4 2.8 2.3 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-met PF12874.7 KIK46630.1 - 4e-06 27.0 8.9 1.2e-05 25.5 3.2 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type SF3a60_bindingd PF12108.8 KIK46630.1 - 5.3e-06 26.2 0.0 1.4e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.8 KIK46630.1 - 5.4e-05 23.4 3.7 5.4e-05 23.4 3.7 2.7 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KIK46630.1 - 0.00053 20.3 1.7 0.031 14.6 0.1 2.8 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 KIK46630.1 - 0.014 15.5 3.5 0.69 10.1 0.1 2.9 2 0 0 2 2 2 0 DBF zinc finger Laps PF10169.9 KIK46630.1 - 0.33 11.5 4.1 0.36 11.4 0.2 2.7 3 0 0 3 3 3 0 Learning-associated protein zf-C2H2_4 PF13894.6 KIK46630.1 - 1.1 10.3 5.5 20 6.4 0.5 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Syja_N PF02383.18 KIK46631.1 - 1.3e-71 241.5 0.0 1.8e-71 241.1 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Snf7 PF03357.21 KIK46632.1 - 7.1e-10 38.8 15.7 1.4e-09 37.8 15.7 1.5 1 1 0 1 1 1 1 Snf7 DMSP_lyase PF16867.5 KIK46632.1 - 0.0099 15.5 0.5 0.047 13.3 0.0 2.1 2 0 0 2 2 2 1 Dimethlysulfonioproprionate lyase BLOC1S3 PF15753.5 KIK46632.1 - 0.021 15.0 0.9 0.021 15.0 0.9 1.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Ist1 PF03398.14 KIK46632.1 - 0.044 13.7 5.2 0.066 13.1 5.2 1.2 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Erv26 PF04148.13 KIK46633.1 - 4.5e-61 206.3 12.5 5.3e-61 206.0 12.5 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF2909 PF11137.8 KIK46633.1 - 0.081 12.9 1.4 0.22 11.5 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) Sld5 PF05916.11 KIK46635.1 - 9.6e-23 80.7 0.5 1.3e-22 80.3 0.5 1.2 1 0 0 1 1 1 1 GINS complex protein Haspin_kinase PF12330.8 KIK46636.1 - 5.4e-62 209.9 0.0 9.7e-62 209.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain DTHCT PF08070.11 KIK46636.1 - 0.53 11.0 8.9 0.17 12.6 0.6 2.9 2 0 0 2 2 2 0 DTHCT (NUC029) region Alpha-amylase_C PF02806.18 KIK46637.1 - 1.8e-26 92.4 0.0 6.4e-26 90.7 0.0 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KIK46637.1 - 5.2e-19 68.4 0.0 1.3e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KIK46637.1 - 1.5e-12 47.8 0.0 1.1e-09 38.4 0.0 2.8 2 1 1 3 3 3 2 Alpha amylase, catalytic domain TFR_dimer PF04253.15 KIK46638.1 - 2.4e-23 82.5 1.0 9.8e-23 80.6 0.1 2.3 2 1 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KIK46638.1 - 1.5e-17 63.9 0.0 5.4e-17 62.1 0.0 1.9 2 1 0 2 2 2 1 Peptidase family M28 PA PF02225.22 KIK46638.1 - 3.8e-11 42.9 0.4 8.7e-11 41.7 0.1 1.7 2 0 0 2 2 2 1 PA domain BRE1 PF08647.11 KIK46638.1 - 0.028 14.5 1.7 0.05 13.7 1.7 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase CheZ PF04344.13 KIK46638.1 - 0.14 12.0 0.1 0.24 11.3 0.1 1.2 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Spermine_synth PF01564.17 KIK46639.1 - 1e-08 34.8 0.0 1.8e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 KIK46639.1 - 0.071 13.8 0.0 0.14 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Retinin_C PF04527.12 KIK46639.1 - 0.45 10.8 3.2 0.68 10.2 1.8 2.0 2 0 0 2 2 2 0 Drosophila Retinin like protein DIOX_N PF14226.6 KIK46641.1 - 2.6e-23 83.0 0.0 4.1e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK46641.1 - 5.8e-16 58.8 0.0 1.1e-15 58.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RCC1 PF00415.18 KIK46642.1 - 1.8e-58 195.0 7.6 3.3e-12 46.8 0.2 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KIK46642.1 - 1.1e-39 133.5 32.0 4.1e-09 36.0 0.7 8.3 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 KIK46642.1 - 0.1 12.3 0.0 5.5 6.7 0.0 2.8 4 0 0 4 4 4 0 TUP1-like enhancer of split SPASM PF13186.6 KIK46642.1 - 0.15 12.6 0.0 18 5.9 0.0 2.6 2 0 0 2 2 2 0 Iron-sulfur cluster-binding domain Aldedh PF00171.22 KIK46643.1 - 1.4e-142 475.5 0.0 1.7e-142 475.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIK46643.1 - 0.032 13.3 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Snf7 PF03357.21 KIK46644.1 - 1.3e-44 151.8 12.8 1.6e-44 151.6 12.8 1.1 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 KIK46644.1 - 0.046 14.2 2.1 19 5.8 1.0 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TRPM_tetra PF16519.5 KIK46644.1 - 0.047 13.8 0.4 0.047 13.8 0.4 2.7 3 0 0 3 3 3 0 Tetramerisation domain of TRPM DUF3573 PF12097.8 KIK46644.1 - 0.32 9.8 1.4 0.37 9.6 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) BST2 PF16716.5 KIK46644.1 - 1.1 9.9 10.2 33 5.1 0.0 2.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Abhydrolase_1 PF00561.20 KIK46648.1 - 3.5e-41 141.5 0.0 7.5e-41 140.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KIK46648.1 - 0.00032 20.4 0.0 0.00051 19.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase P21-Arc PF04062.14 KIK46652.1 - 4.6e-77 258.0 0.0 5.2e-77 257.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit NOB1_Zn_bind PF08772.11 KIK46653.1 - 1.3e-30 105.4 0.6 2.1e-30 104.7 0.6 1.3 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KIK46653.1 - 1.7e-27 95.7 0.0 3.3e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 PIN domain of ribonuclease zf-NADH-PPase PF09297.11 KIK46653.1 - 0.018 14.7 2.0 0.13 12.0 0.2 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-C2HC5 PF06221.13 KIK46653.1 - 0.088 12.8 1.8 0.16 12.0 1.8 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Iso_dh PF00180.20 KIK46654.1 - 1.8e-122 408.9 0.0 2.1e-122 408.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Vps5 PF09325.10 KIK46655.1 - 5.5e-17 62.1 1.1 7.3e-17 61.7 1.1 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KIK46655.1 - 8.4e-13 48.3 0.0 2.5e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 PX domain Baculo_F PF12259.8 KIK46655.1 - 0.18 10.3 1.0 0.25 9.8 1.0 1.1 1 0 0 1 1 1 0 Baculovirus F protein GTP_cyclohydro2 PF00925.20 KIK46656.1 - 5.7e-60 201.6 0.0 9e-60 201.0 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF3638 PF12340.8 KIK46657.1 - 0.06 12.7 0.0 6.3 6.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3638) ZapB PF06005.12 KIK46658.1 - 0.89 10.0 12.5 6.8 7.2 4.6 2.9 1 1 1 2 2 2 0 Cell division protein ZapB SHR3_chaperone PF08229.11 KIK46659.1 - 0.16 10.9 4.9 3.3 6.6 0.1 3.0 3 1 1 4 4 4 0 ER membrane protein SH3 ECF_trnsprt PF12822.7 KIK46659.1 - 0.23 11.6 11.7 1.6 8.8 10.0 2.6 2 1 0 2 2 2 0 ECF transporter, substrate-specific component FMO-like PF00743.19 KIK46660.1 - 4.9e-13 48.4 0.2 7.4e-12 44.5 0.2 2.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KIK46660.1 - 2.2e-06 27.1 0.0 1.2e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KIK46660.1 - 2.8e-05 24.3 0.1 0.00015 21.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIK46660.1 - 0.00014 21.3 0.0 0.00072 18.9 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KIK46660.1 - 0.18 11.0 0.0 0.33 10.2 0.0 1.4 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase Pex14_N PF04695.13 KIK46661.1 - 2.6e-11 44.4 0.4 2.6e-11 44.4 0.4 3.8 3 1 1 4 4 4 2 Peroxisomal membrane anchor protein (Pex14p) conserved region RSN1_TM PF13967.6 KIK46661.1 - 0.19 11.5 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport SKN1 PF03935.15 KIK46662.1 - 1.7e-189 630.4 1.5 2e-189 630.2 1.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) adh_short PF00106.25 KIK46665.1 - 1.3e-38 132.5 0.4 1.9e-38 131.9 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK46665.1 - 8e-26 91.0 0.0 1.1e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK46665.1 - 1.7e-10 41.1 0.7 3.8e-09 36.7 0.7 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK46665.1 - 0.08 12.4 0.2 0.21 11.0 0.1 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family VD10_N PF08476.10 KIK46666.1 - 0.17 11.6 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 Viral D10 N-terminal ACT_7 PF13840.6 KIK46667.1 - 2.2e-18 65.8 0.0 1.4e-11 44.0 0.0 2.4 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 KIK46667.1 - 0.099 12.4 0.1 2 8.2 0.0 2.6 2 0 0 2 2 2 0 ACT domain CRAL_TRIO_2 PF13716.6 KIK46668.1 - 0.046 13.9 0.2 0.098 12.8 0.2 1.7 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain PP2C PF00481.21 KIK46670.1 - 6.1e-31 108.0 0.0 1.1e-27 97.4 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KIK46670.1 - 1.9e-06 27.7 0.0 6.3e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C DUF2914 PF11141.8 KIK46670.1 - 0.17 11.7 1.4 2.5 7.9 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2914) UCH PF00443.29 KIK46671.1 - 2.4e-47 161.6 0.0 3.8e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIK46671.1 - 4.6e-23 82.3 0.0 1.3e-22 80.8 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2175 PF09943.9 KIK46671.1 - 0.098 13.0 0.5 0.19 12.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Peptidase_C98 PF15499.6 KIK46671.1 - 0.37 10.2 2.3 1.7 8.0 2.3 2.2 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase zf_UBZ PF18439.1 KIK46671.1 - 0.42 10.3 2.5 2.9 7.6 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger NUDE_C PF04880.13 KIK46671.1 - 1.4 9.3 17.8 0.24 11.8 12.9 2.0 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region DTHCT PF08070.11 KIK46671.1 - 8.5 7.2 18.3 23 5.8 2.2 3.8 3 0 0 3 3 3 0 DTHCT (NUC029) region zf-H2C2_2 PF13465.6 KIK46672.1 - 2.2e-18 65.8 22.3 1.9e-08 34.4 0.2 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KIK46672.1 - 1.4e-16 59.9 23.9 2.1e-05 24.7 1.1 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK46672.1 - 3.7e-11 42.9 20.2 0.00075 20.1 0.7 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 KIK46672.1 - 0.00025 21.3 5.5 1.7 9.2 0.2 3.9 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIK46672.1 - 0.0019 18.5 4.2 1.9 8.9 0.2 3.7 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KIK46672.1 - 0.0064 16.1 4.1 2.6 7.7 0.2 3.4 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 KIK46672.1 - 0.012 15.6 20.3 0.022 14.8 1.1 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 KIK46672.1 - 0.024 15.2 4.5 4.8 7.9 0.0 3.2 2 1 2 4 4 4 0 FOXP coiled-coil domain PRP21_like_P PF12230.8 KIK46672.1 - 0.17 11.7 0.1 0.22 11.4 0.1 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zinc_ribbon_15 PF17032.5 KIK46672.1 - 0.24 12.2 4.6 4.9 8.0 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon family C1_4 PF07975.12 KIK46672.1 - 0.29 11.4 8.3 0.34 11.2 1.9 2.9 1 1 2 3 3 3 0 TFIIH C1-like domain zf-C2H2_2 PF12756.7 KIK46672.1 - 0.34 11.2 7.4 2.4 8.5 0.1 3.0 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.18 KIK46672.1 - 0.83 10.4 8.5 0.35 11.6 0.7 2.7 3 0 0 3 3 3 0 TRAF-type zinc finger DUF4764 PF15961.5 KIK46672.1 - 1.7 7.2 7.7 3.5 6.2 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4764) F-box-like PF12937.7 KIK46673.1 - 5.4e-06 26.2 0.6 5.4e-06 26.2 0.6 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK46673.1 - 6.8e-06 25.8 1.2 1.6e-05 24.7 1.2 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KIK46673.1 - 0.00028 20.8 0.0 0.00028 20.8 0.0 2.2 2 0 0 2 2 2 1 F-box Arteri_Gl PF00951.18 KIK46674.1 - 0.014 15.2 0.5 0.021 14.6 0.3 1.3 1 1 0 1 1 1 0 Arterivirus GL envelope glycoprotein Prefoldin_2 PF01920.20 KIK46675.1 - 3.5e-22 78.4 0.5 4.6e-22 78.0 0.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit APG6_N PF17675.1 KIK46675.1 - 0.0019 18.8 3.0 1.5 9.3 0.0 2.1 2 0 0 2 2 2 2 Apg6 coiled-coil region OmpH PF03938.14 KIK46675.1 - 0.0032 17.8 1.1 1.2 9.5 1.0 2.1 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) Phage_Mu_Gam PF07352.12 KIK46675.1 - 0.0065 16.4 0.1 0.01 15.7 0.1 1.3 1 1 0 1 1 1 1 Bacteriophage Mu Gam like protein Prefoldin PF02996.17 KIK46675.1 - 0.012 15.6 1.5 0.26 11.2 1.5 2.1 1 1 0 1 1 1 0 Prefoldin subunit DASH_Dad3 PF08656.10 KIK46675.1 - 0.013 15.5 0.5 0.026 14.6 0.2 1.6 2 0 0 2 2 2 0 DASH complex subunit Dad3 Helo_like_N PF17111.5 KIK46675.1 - 0.025 13.9 1.3 0.31 10.4 0.6 2.0 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins LegC3_N PF18654.1 KIK46675.1 - 0.039 13.2 0.3 0.042 13.1 0.3 1.0 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain GrpE PF01025.19 KIK46675.1 - 0.054 13.2 0.8 1.3 8.7 0.0 2.0 2 0 0 2 2 2 0 GrpE SlyX PF04102.12 KIK46675.1 - 0.072 13.7 1.2 0.34 11.6 0.6 2.1 2 0 0 2 2 2 0 SlyX Cep57_MT_bd PF06657.13 KIK46675.1 - 0.076 13.5 0.7 17 6.0 0.0 2.4 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF4924 PF16271.5 KIK46675.1 - 0.089 12.8 0.0 0.13 12.3 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4924) DASH_Spc19 PF08287.11 KIK46675.1 - 0.13 12.2 3.0 0.1 12.5 1.2 1.6 2 0 0 2 2 2 0 Spc19 ZapB PF06005.12 KIK46675.1 - 0.16 12.4 3.6 0.42 11.1 3.1 1.9 1 1 1 2 2 2 0 Cell division protein ZapB PI3K_P85_iSH2 PF16454.5 KIK46675.1 - 0.19 11.3 2.8 4.5 6.8 1.1 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HALZ PF02183.18 KIK46675.1 - 0.4 10.9 3.8 12 6.2 0.1 2.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper Fer4 PF00037.27 KIK46676.1 - 5.6e-14 51.3 17.5 1.9e-08 33.8 4.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KIK46676.1 - 1.1e-12 48.3 10.5 1.1e-12 48.3 10.5 1.5 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KIK46676.1 - 2e-10 41.5 10.1 1.7e-05 25.6 0.8 2.3 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KIK46676.1 - 8.3e-10 38.7 5.3 0.00021 21.4 0.4 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KIK46676.1 - 3.1e-09 36.8 21.4 1.2e-06 28.5 12.2 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KIK46676.1 - 1.7e-08 34.8 17.0 3.2e-05 24.3 10.3 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KIK46676.1 - 2.3e-08 34.0 10.7 4.3e-08 33.2 10.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KIK46676.1 - 4.2e-07 29.8 17.8 0.00043 20.2 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KIK46676.1 - 1.2e-06 28.3 11.7 0.0025 17.8 1.7 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KIK46676.1 - 6.7e-06 26.2 11.0 0.00035 20.9 1.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KIK46676.1 - 0.00015 22.2 11.2 0.023 15.3 12.5 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 KIK46676.1 - 0.0013 19.2 11.2 0.14 12.7 0.6 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 KIK46676.1 - 0.0048 17.1 5.5 0.77 10.0 0.4 2.3 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 KIK46676.1 - 0.035 14.3 8.9 0.96 9.7 1.2 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 KIK46676.1 - 0.37 11.7 12.0 2.9 8.8 2.1 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain ETF_QO PF05187.13 KIK46676.1 - 3.2 8.0 10.1 1.8 8.7 0.7 2.5 2 1 1 3 3 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_3 PF12798.7 KIK46676.1 - 9 7.5 21.8 0.37 11.8 4.1 2.6 3 0 0 3 3 2 0 4Fe-4S binding domain Syntaxin-6_N PF09177.11 KIK46678.1 - 0.11 13.0 0.1 0.21 12.2 0.1 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF724 PF05266.14 KIK46678.1 - 0.17 11.7 0.7 0.28 11.0 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Serglycin PF04360.12 KIK46678.1 - 7.9 6.4 9.6 4.6 7.2 6.6 2.2 1 1 1 2 2 2 0 Serglycin bZIP_1 PF00170.21 KIK46678.1 - 8.6 6.5 11.9 0.99 9.5 6.2 2.3 3 0 0 3 3 3 0 bZIP transcription factor GRIM-19 PF06212.12 KIK46679.1 - 1.9e-30 105.5 0.0 2.2e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein HMG_box PF00505.19 KIK46680.1 - 8.9e-13 48.5 15.7 3.4e-06 27.4 5.1 3.2 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK46680.1 - 4.6e-12 46.3 12.9 1.9e-06 28.4 3.5 2.8 3 1 0 3 3 3 2 HMG-box domain Acetyltransf_7 PF13508.7 KIK46681.1 - 2.2e-06 28.0 0.0 3.6e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK46681.1 - 1.3e-05 25.4 0.5 2.5e-05 24.5 0.5 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK46681.1 - 0.00025 21.0 0.7 0.00095 19.1 0.7 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 KIK46681.1 - 0.0013 19.4 0.0 0.081 13.6 0.0 2.4 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain PPR_2 PF13041.6 KIK46682.1 - 6.2e-31 106.4 0.3 3.5e-06 27.1 0.0 10.3 6 1 5 11 11 11 10 PPR repeat family PPR PF01535.20 KIK46682.1 - 9.1e-31 103.9 0.9 0.11 12.7 0.0 12.3 13 0 0 13 13 13 9 PPR repeat PPR_3 PF13812.6 KIK46682.1 - 3.7e-30 103.8 0.0 1.2e-05 25.3 0.0 7.6 7 1 0 7 7 7 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 KIK46682.1 - 2.6e-14 52.6 7.1 0.0018 18.0 0.1 8.3 10 0 0 10 10 10 3 PPR repeat PPR_long PF17177.4 KIK46682.1 - 2.1e-10 40.3 0.7 0.005 16.2 0.1 4.9 3 1 3 6 6 6 4 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KIK46682.1 - 0.00012 22.6 9.5 5.7 8.0 0.0 9.0 7 3 3 10 10 10 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK46682.1 - 0.063 13.3 0.2 34 4.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat FlbT PF07378.11 KIK46682.1 - 0.2 11.7 0.4 6.2 6.9 0.0 3.1 3 0 0 3 3 3 0 Flagellar protein FlbT Velvet PF11754.8 KIK46683.1 - 6e-82 275.3 15.5 4.7e-80 269.2 15.5 2.3 1 1 0 1 1 1 1 Velvet factor ArfGap PF01412.18 KIK46684.1 - 2.9e-33 114.4 0.0 6.6e-33 113.3 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Apo-CIII PF05778.12 KIK46684.1 - 0.079 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Carboxyl_trans PF01039.22 KIK46685.1 - 6.7e-131 437.3 0.1 8.4e-131 437.0 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KIK46685.1 - 0.00033 20.2 1.2 0.084 12.3 0.1 2.2 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) DNA_mis_repair PF01119.19 KIK46686.1 - 5.6e-13 48.6 0.4 1.5e-11 44.0 0.4 2.3 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KIK46686.1 - 2.9e-08 33.6 0.0 5.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KIK46686.1 - 1.5e-05 24.8 0.0 0.00036 20.3 0.0 2.5 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 KIK46686.1 - 7.2e-05 23.3 0.0 0.00015 22.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SBDS PF01172.18 KIK46687.1 - 7e-18 64.5 0.1 9.1e-18 64.1 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein ABM PF03992.16 KIK46688.1 - 9.3e-05 22.5 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase AFG1_ATPase PF03969.16 KIK46689.1 - 1.1e-89 300.9 0.0 1.6e-86 290.5 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KIK46689.1 - 1.7e-05 25.3 0.0 0.017 15.5 0.0 2.6 1 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KIK46689.1 - 0.00038 20.9 0.0 0.0013 19.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK46689.1 - 0.011 16.0 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KIK46689.1 - 0.069 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein TsaE PF02367.17 KIK46689.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KIK46689.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KIK46689.1 - 0.17 11.9 0.0 0.47 10.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) WD40 PF00400.32 KIK46691.1 - 8.7e-27 92.8 2.1 7.3e-07 29.8 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK46691.1 - 1.5e-09 38.0 0.1 0.0076 16.5 0.0 3.9 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK46691.1 - 8e-06 25.0 0.1 0.038 12.9 0.0 2.8 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK46691.1 - 0.0022 17.9 0.0 39 4.3 0.0 4.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF3035 PF11233.8 KIK46691.1 - 0.039 14.2 1.5 0.092 13.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3035) WSK PF03832.13 KIK46692.1 - 0.061 13.0 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 WSK motif Pkinase_Tyr PF07714.17 KIK46693.1 - 1.2e-37 129.6 0.0 1.9e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK46693.1 - 4.4e-31 108.2 0.0 2.6e-30 105.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK46693.1 - 0.0017 18.3 0.0 0.023 14.6 0.1 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family GrlR PF16518.5 KIK46693.1 - 0.008 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 T3SS negative regulator,GrlR Kdo PF06293.14 KIK46693.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 KIK46693.1 - 0.024 14.8 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Ceramidse_alk_C PF17048.5 KIK46693.1 - 0.058 13.3 0.4 0.26 11.1 0.0 2.2 3 0 0 3 3 3 0 Neutral/alkaline non-lysosomal ceramidase, C-terminal RNF220 PF15926.5 KIK46694.1 - 1.2e-20 74.2 2.6 1.2e-20 74.2 2.6 2.3 2 1 0 2 2 2 1 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 KIK46694.1 - 4.1e-08 32.9 15.3 4.1e-08 32.9 15.3 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK46694.1 - 1.7e-05 24.5 20.2 0.00017 21.4 13.0 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK46694.1 - 0.0002 21.2 21.2 0.00029 20.7 13.8 3.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KIK46694.1 - 0.00028 20.7 15.0 0.00028 20.7 15.0 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK46694.1 - 0.0012 18.8 8.1 0.0012 18.8 8.1 3.0 3 1 0 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KIK46694.1 - 0.0055 16.5 17.9 0.034 14.0 11.4 3.1 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KIK46694.1 - 0.0064 16.8 16.3 0.0064 16.8 16.3 3.2 3 0 0 3 3 3 1 Ring finger domain zf-WRNIP1_ubi PF18279.1 KIK46694.1 - 0.031 14.9 7.1 19 6.2 0.1 3.6 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Vps39_2 PF10367.9 KIK46694.1 - 0.35 11.3 0.1 0.35 11.3 0.1 2.6 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 zf-RING_6 PF14835.6 KIK46694.1 - 1.5 8.8 10.5 1.6 8.7 7.5 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Zn-C2H2_12 PF18112.1 KIK46694.1 - 7.1 7.2 6.6 36 5.0 0.3 3.5 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Tom7 PF08038.12 KIK46696.1 - 2.2e-21 75.2 0.6 2.5e-21 75.1 0.6 1.0 1 0 0 1 1 1 1 TOM7 family JAB PF01398.21 KIK46697.1 - 2e-22 79.4 0.0 3.4e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KIK46697.1 - 6.3e-15 55.6 0.0 1.2e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UreF PF01730.16 KIK46698.1 - 1.3e-26 93.8 0.0 1.6e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 UreF Rif1_N PF12231.8 KIK46698.1 - 0.21 10.5 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal RRM_1 PF00076.22 KIK46699.1 - 8.5e-09 35.1 0.1 2.3e-06 27.3 0.0 3.6 3 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) pKID PF02173.17 KIK46699.1 - 0.16 11.5 0.9 0.42 10.1 0.9 1.7 1 0 0 1 1 1 0 pKID domain HAD_2 PF13419.6 KIK46705.1 - 1.3e-18 67.7 0.0 2.4e-18 66.9 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK46705.1 - 2.5e-10 41.0 0.7 4.7e-08 33.6 0.7 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIK46705.1 - 2.9e-06 27.8 0.0 3.6e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KIK46705.1 - 0.00015 21.8 0.0 0.065 13.4 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIK46705.1 - 0.033 14.3 0.0 0.079 13.0 0.0 1.7 2 0 0 2 2 2 0 HAD-hyrolase-like Glutaredoxin PF00462.24 KIK46706.1 - 3.3e-05 24.0 0.0 5.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Prion_bPrPp PF11587.8 KIK46709.1 - 0.059 13.2 2.6 4.7 7.1 0.1 2.7 3 0 0 3 3 3 0 Major prion protein bPrPp - N terminal Glyco_transf_43 PF03360.16 KIK46713.1 - 0.18 11.6 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 43 AMP-binding PF00501.28 KIK46714.1 - 1.5e-42 145.7 0.0 2e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KIK46714.1 - 7.3e-05 22.6 0.1 0.00014 21.7 0.1 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Peripla_BP_6 PF13458.6 KIK46714.1 - 0.0094 15.6 0.1 0.027 14.2 0.2 1.6 2 0 0 2 2 2 1 Periplasmic binding protein RHD3 PF05879.12 KIK46716.1 - 6.7e-244 811.4 7.8 6.2e-243 808.2 7.8 1.9 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KIK46716.1 - 4.6e-06 26.1 0.1 1.1e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 KIK46716.1 - 5e-06 26.6 0.1 2e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KIK46716.1 - 2.3e-05 24.5 0.1 6.2e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Dynamin family AAA_28 PF13521.6 KIK46716.1 - 0.0036 17.6 0.0 0.0092 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2523 PF10734.9 KIK46716.1 - 0.061 13.9 0.2 1.3 9.7 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2523) Saf_2TM PF18303.1 KIK46718.1 - 0.058 13.0 3.4 0.12 12.0 3.4 1.5 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain SecG PF03840.14 KIK46718.1 - 0.12 12.4 0.8 0.12 12.4 0.8 2.3 2 0 0 2 2 2 0 Preprotein translocase SecG subunit FtsX PF02687.21 KIK46718.1 - 7.6 7.1 12.1 0.34 11.4 5.7 1.9 2 0 0 2 2 2 0 FtsX-like permease family DUF3100 PF11299.8 KIK46720.1 - 0.071 12.5 1.2 0.28 10.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3100) Striatin PF08232.12 KIK46720.1 - 0.17 12.5 13.6 0.23 12.0 6.9 2.8 2 0 0 2 2 2 0 Striatin family DUF3439 PF11921.8 KIK46720.1 - 0.99 9.4 9.1 3 7.8 1.5 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) TMEM215 PF15746.5 KIK46720.1 - 1.4 8.3 3.5 3.3 7.1 3.5 1.6 1 0 0 1 1 1 0 TMEM215 family AP3D1 PF06375.11 KIK46720.1 - 3.7 7.8 16.9 6.3 7.0 11.2 2.7 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Peptidase_S49_N PF08496.10 KIK46720.1 - 4.9 7.2 12.3 5.9 6.9 7.2 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SpoIIIAH PF12685.7 KIK46720.1 - 9.8 5.9 17.0 8.7 6.1 1.4 2.5 2 0 0 2 2 2 0 SpoIIIAH-like protein FAO_M PF16350.5 KIK46721.1 - 0.074 13.4 2.7 0.41 11.0 1.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase central domain TPR_15 PF13429.6 KIK46722.1 - 0.0065 15.7 0.1 0.48 9.6 0.0 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK46722.1 - 0.019 15.0 0.2 3.4 7.9 0.0 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIK46722.1 - 0.027 14.3 0.2 12 6.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK46722.1 - 0.14 13.1 0.7 16 6.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK46722.1 - 0.22 11.2 0.8 1 9.1 0.0 2.4 3 1 0 3 3 3 0 TPR repeat TPR_1 PF00515.28 KIK46722.1 - 0.3 11.0 1.4 1.6 8.7 0.0 2.8 4 0 0 4 4 4 0 Tetratricopeptide repeat BAR PF03114.18 KIK46725.1 - 6.4e-50 170.0 4.9 7.7e-50 169.8 4.9 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.13 KIK46725.1 - 3.1e-05 23.7 2.9 0.00052 19.7 0.4 2.2 2 0 0 2 2 2 1 Arfaptin-like domain IFT57 PF10498.9 KIK46725.1 - 0.001 18.1 0.7 0.0018 17.3 0.1 1.7 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 EzrA PF06160.12 KIK46725.1 - 0.0014 16.9 4.5 0.23 9.6 0.2 2.1 2 0 0 2 2 2 2 Septation ring formation regulator, EzrA SYF2 PF08231.12 KIK46725.1 - 0.005 17.2 4.9 0.011 16.1 4.9 1.6 1 1 0 1 1 1 1 SYF2 splicing factor AAA_13 PF13166.6 KIK46725.1 - 0.0058 15.3 0.6 0.0086 14.8 0.6 1.4 1 0 0 1 1 1 1 AAA domain RPW8 PF05659.11 KIK46725.1 - 0.033 13.9 0.6 0.31 10.7 0.1 2.3 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 GAS PF13851.6 KIK46725.1 - 0.068 12.5 3.6 0.56 9.5 0.1 2.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 KIK46725.1 - 0.37 11.0 4.1 0.35 11.1 0.8 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 TMPIT PF07851.13 KIK46725.1 - 2.3 7.4 3.5 17 4.6 0.4 2.1 1 1 1 2 2 2 0 TMPIT-like protein BRE1 PF08647.11 KIK46725.1 - 3.5 7.8 9.2 0.22 11.6 1.1 2.8 3 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase TMEM61 PF15105.6 KIK46727.1 - 0.11 12.3 0.1 0.85 9.4 0.0 2.0 2 0 0 2 2 2 0 TMEM61 protein family UvdE PF03851.14 KIK46730.1 - 5.5e-88 294.8 0.0 7.2e-88 294.4 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF4037 PF13228.6 KIK46730.1 - 0.05 14.4 0.0 0.21 12.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4037) Myb_Cef PF11831.8 KIK46731.1 - 5.1e-63 212.8 0.1 5.1e-63 212.8 0.1 4.1 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KIK46731.1 - 7.7e-21 74.0 4.8 9.4e-11 41.7 1.3 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK46731.1 - 1e-16 60.9 5.8 3.4e-12 46.4 2.9 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Met_synt_B12 PF02965.17 KIK46731.1 - 0.0044 16.5 2.3 0.036 13.5 0.2 2.5 2 0 0 2 2 2 1 Vitamin B12 dependent methionine synthase, activation domain HAUS-augmin3 PF14932.6 KIK46731.1 - 0.39 10.3 5.9 0.64 9.5 4.3 2.2 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF2367 PF10164.9 KIK46733.1 - 8.2e-07 29.5 10.6 1.1e-05 25.9 10.6 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) PepSY_TM PF03929.16 KIK46733.1 - 0.025 14.3 0.0 0.03 14.0 0.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Methyltransf_25 PF13649.6 KIK46734.1 - 2.6e-14 53.7 0.2 8.8e-14 52.0 0.0 2.0 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK46734.1 - 9.4e-14 51.5 0.1 1.6e-13 50.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KIK46734.1 - 9.5e-12 44.9 0.0 1.5e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KIK46734.1 - 5.4e-11 43.0 0.0 1.5e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK46734.1 - 1.7e-08 34.5 0.0 6.9e-08 32.5 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KIK46734.1 - 1.5e-07 31.0 0.0 2.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KIK46734.1 - 1.6e-07 32.0 0.0 3.4e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KIK46734.1 - 6.1e-07 28.7 0.0 1.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 KIK46734.1 - 4.1e-06 26.4 0.1 6.9e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KIK46734.1 - 7.8e-05 22.1 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 KIK46734.1 - 0.0002 21.3 0.1 0.00034 20.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KIK46734.1 - 0.00021 20.7 0.0 0.00034 20.1 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 KIK46734.1 - 0.00038 20.5 0.0 0.00065 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIK46734.1 - 0.00055 19.8 0.1 0.001 18.9 0.1 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 KIK46734.1 - 0.001 18.4 0.0 0.0026 17.1 0.0 1.7 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_16 PF10294.9 KIK46734.1 - 0.0016 18.2 0.1 0.0027 17.5 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 KIK46734.1 - 0.002 18.3 0.0 0.0045 17.1 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_24 PF13578.6 KIK46734.1 - 0.0078 17.2 0.0 0.02 15.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KIK46734.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PRMT5 PF05185.16 KIK46734.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_4 PF02390.17 KIK46734.1 - 0.18 11.3 0.1 0.34 10.4 0.1 1.4 1 0 0 1 1 1 0 Putative methyltransferase Abhydrolase_1 PF00561.20 KIK46735.1 - 1.8e-23 83.5 0.7 3.4e-22 79.3 0.7 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK46735.1 - 9e-17 62.4 0.0 1.2e-16 61.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK46735.1 - 3.4e-09 36.3 0.0 4.7e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KIK46735.1 - 0.00059 18.6 0.0 0.00094 18.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family Chlorophyllase2 PF12740.7 KIK46735.1 - 0.0088 15.0 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KIK46735.1 - 0.02 13.9 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase adh_short PF00106.25 KIK46738.1 - 5.7e-16 58.5 0.0 9.2e-13 48.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK46738.1 - 4.6e-06 26.4 0.0 2.8e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK46738.1 - 0.00013 21.9 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 KR domain GATase_5 PF13507.6 KIK46740.1 - 3.5e-99 331.1 0.0 5e-99 330.6 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KIK46740.1 - 2.1e-42 144.9 0.5 4.7e-30 104.8 0.3 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KIK46740.1 - 1.1e-30 105.9 0.0 2.9e-30 104.6 0.0 1.7 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KIK46740.1 - 1.1e-21 77.1 0.0 2.6e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 KIK46740.1 - 0.044 14.4 0.4 1.3 9.7 0.0 2.6 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain PX PF00787.24 KIK46741.1 - 7.9e-26 90.3 0.0 9.7e-26 90.0 0.0 1.1 1 0 0 1 1 1 1 PX domain Trs65 PF12735.7 KIK46742.1 - 6.3e-07 29.1 0.0 0.0077 15.7 0.0 2.4 2 0 0 2 2 2 2 TRAPP trafficking subunit Trs65 ELP6 PF09807.9 KIK46743.1 - 4e-16 59.2 0.3 1.4e-15 57.4 0.3 1.7 1 1 0 1 1 1 1 Elongation complex protein 6 Elong_Iki1 PF10483.9 KIK46743.1 - 0.00026 20.6 0.2 0.00039 20.0 0.2 1.2 1 0 0 1 1 1 1 Elongator subunit Iki1 Sec34 PF04136.15 KIK46744.1 - 5e-47 159.5 0.0 1.7e-46 157.8 0.0 2.0 2 0 0 2 2 2 1 Sec34-like family SapB_1 PF05184.15 KIK46744.1 - 0.33 11.0 1.8 12 6.1 0.0 4.0 4 0 0 4 4 4 0 Saposin-like type B, region 1 Sec2p PF06428.11 KIK46746.1 - 1.4e-10 41.0 9.6 1.4e-10 41.0 9.6 2.1 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p Stb3 PF10330.9 KIK46746.1 - 0.067 13.2 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Putative Sin3 binding protein BioW PF03744.13 KIK46746.1 - 0.45 10.0 3.3 12 5.4 0.8 2.2 2 0 0 2 2 2 0 6-carboxyhexanoate--CoA ligase NES_C_h PF18208.1 KIK46746.1 - 1.7 8.9 5.4 0.39 11.0 1.4 2.0 2 0 0 2 2 2 0 Nicking enzyme C-terminal middle helical domain DUF4140 PF13600.6 KIK46746.1 - 2.9 8.4 11.4 8.5 6.9 2.5 3.3 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DIOX_N PF14226.6 KIK46749.1 - 8.8e-32 110.3 0.0 1.9e-31 109.3 0.0 1.5 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK46749.1 - 1.5e-18 67.2 0.0 2.7e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BCS1_N PF08740.11 KIK46752.1 - 5.4e-45 153.7 3.0 1.1e-44 152.6 3.0 1.6 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KIK46752.1 - 4.2e-14 53.1 0.0 1.4e-06 28.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KIK46752.1 - 0.00016 21.4 0.4 0.0094 15.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.13 KIK46752.1 - 0.00042 19.6 0.0 0.00084 18.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_23 PF13476.6 KIK46752.1 - 0.0012 19.4 18.8 0.37 11.3 14.1 3.5 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KIK46752.1 - 0.0019 18.6 3.0 0.0051 17.2 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 KIK46752.1 - 0.0056 16.4 0.2 0.016 14.9 0.1 1.8 1 1 1 2 2 2 1 Viral (Superfamily 1) RNA helicase ssDNA_TraI_N PF18272.1 KIK46752.1 - 0.038 14.0 0.1 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain AAA_33 PF13671.6 KIK46752.1 - 0.072 13.2 1.5 0.17 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KIK46752.1 - 0.088 13.3 1.2 0.29 11.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter CENP-Q PF13094.6 KIK46752.1 - 0.13 12.5 16.6 0.31 11.2 16.6 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4407 PF14362.6 KIK46752.1 - 0.18 11.1 8.8 0.28 10.5 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_11 PF13086.6 KIK46752.1 - 0.4 10.4 7.7 30 4.3 6.5 2.7 3 0 0 3 3 3 0 AAA domain DUF4355 PF14265.6 KIK46752.1 - 0.73 10.1 21.0 1.4 9.2 21.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Sensor PF13796.6 KIK46753.1 - 0.003 17.6 16.2 0.023 14.7 15.7 2.3 1 1 0 1 1 1 1 Putative sensor G-alpha PF00503.20 KIK46754.1 - 2e-119 398.9 0.0 2.3e-119 398.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIK46754.1 - 1.2e-16 60.6 0.6 1.1e-11 44.5 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIK46754.1 - 6.7e-05 22.4 1.1 0.0041 16.5 0.0 2.6 2 1 1 3 3 3 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KIK46754.1 - 0.0046 17.2 0.3 2.9 8.1 0.0 2.6 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KIK46754.1 - 0.042 13.9 0.1 1.4 9.0 0.1 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KIK46754.1 - 0.059 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KIK46754.1 - 0.14 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Cyt-b5 PF00173.28 KIK46756.1 - 2.9e-10 40.2 0.0 3.5e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain T3SS_ExsE PF18286.1 KIK46757.1 - 0.052 13.5 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Type III secretion system ExsE Zn_clus PF00172.18 KIK46758.1 - 1.8e-08 34.4 14.0 5.6e-08 32.8 14.0 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FLYWCH PF04500.16 KIK46762.1 - 0.074 13.2 1.6 0.78 9.9 0.4 2.2 2 0 0 2 2 2 0 FLYWCH zinc finger domain DUF832 PF05734.11 KIK46763.1 - 0.02 14.4 0.2 0.024 14.2 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) MMtag PF10159.9 KIK46764.1 - 1.3e-30 105.5 2.7 1.3e-30 105.5 2.7 2.8 3 0 0 3 3 3 1 Multiple myeloma tumor-associated PAP1 PF08601.10 KIK46764.1 - 0.11 12.2 4.8 0.13 12.0 4.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 U1snRNP70_N PF12220.8 KIK46764.1 - 3 8.5 13.2 0.058 14.0 2.9 2.7 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PWWP PF00855.17 KIK46766.1 - 1.9e-19 69.8 0.1 5.4e-19 68.4 0.1 1.8 1 0 0 1 1 1 1 PWWP domain Med26 PF08711.11 KIK46766.1 - 0.0017 18.3 0.0 0.005 16.8 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain SWIRM-assoc_2 PF16496.5 KIK46766.1 - 0.98 8.2 17.8 1.3 7.8 17.8 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Pterin_4a PF01329.19 KIK46767.1 - 2.1e-17 63.1 0.0 4.4e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Aldo_ket_red PF00248.21 KIK46768.1 - 1.9e-24 86.4 0.0 1.6e-22 80.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family zf-CCHC PF00098.23 KIK46769.1 - 2.7e-10 39.8 27.8 3.3e-05 23.8 1.3 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 KIK46769.1 - 0.00067 19.4 19.8 0.016 15.0 0.4 4.1 4 0 0 4 4 4 3 Zinc knuckle Mitofilin PF09731.9 KIK46769.1 - 0.045 12.6 3.7 0.063 12.1 3.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein zf-CCHC_4 PF14392.6 KIK46769.1 - 2.9 7.7 22.5 1.1 9.0 0.4 4.4 4 0 0 4 4 4 0 Zinc knuckle CDC45 PF02724.14 KIK46769.1 - 7.7 4.7 10.6 5.9 5.1 9.1 1.4 2 0 0 2 2 2 0 CDC45-like protein E1-E2_ATPase PF00122.20 KIK46770.1 - 6.6e-38 130.0 3.5 6.6e-38 130.0 3.5 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KIK46770.1 - 1.3e-18 68.1 0.1 1.5e-16 61.3 0.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KIK46770.1 - 2.9e-14 53.2 2.4 2.9e-14 53.2 2.4 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KIK46770.1 - 4.7e-09 35.8 0.0 1e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KIK46770.1 - 2e-05 24.6 0.0 4.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KIK46770.1 - 0.0041 16.9 1.1 0.035 13.9 0.4 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Prot_ATP_ID_OB PF16450.5 KIK46770.1 - 0.091 12.7 0.2 0.6 10.1 0.0 2.4 2 1 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain Yippee-Mis18 PF03226.14 KIK46772.1 - 5e-15 55.6 0.0 6.1e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PhnA_Zn_Ribbon PF08274.12 KIK46772.1 - 0.012 15.6 0.1 0.021 14.8 0.1 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Vps53_N PF04100.12 KIK46773.1 - 5.9e-92 308.6 0.9 1e-91 307.8 0.9 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 KIK46773.1 - 1.8e-05 24.2 11.1 0.00016 21.0 7.3 2.4 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex VPS53_C PF16854.5 KIK46773.1 - 2e-05 24.6 1.1 0.00033 20.6 0.0 3.0 3 1 0 3 3 3 1 Vacuolar protein sorting-associated protein 53 C-terminus DUF2451 PF10474.9 KIK46773.1 - 0.0053 16.6 0.2 0.019 14.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Homoserine_dh PF00742.19 KIK46773.1 - 0.0087 16.0 0.3 0.021 14.7 0.3 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase Herpes_UL42 PF02282.16 KIK46773.1 - 0.041 13.8 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 DNA polymerase processivity factor (UL42) DUF1664 PF07889.12 KIK46773.1 - 0.063 13.3 8.8 0.019 15.0 3.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RRP36 PF06102.12 KIK46773.1 - 0.48 10.4 5.2 1.2 9.1 5.2 1.7 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 NBD94 PF16830.5 KIK46773.1 - 0.73 10.3 2.9 1.2 9.6 1.7 2.0 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH GIT1_C PF12205.8 KIK46773.1 - 2.4 8.3 7.8 1.2 9.3 0.5 3.1 3 1 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term Fib_alpha PF08702.10 KIK46773.1 - 4.3 7.5 7.7 10 6.3 6.6 2.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family MapZ_EC1 PF18041.1 KIK46773.1 - 4.8 7.4 6.6 1.7 8.9 2.9 2.2 2 1 0 2 2 2 0 MapZ extracellular domain 1 Amnionless PF14828.6 KIK46774.1 - 0.0028 16.5 0.0 0.0037 16.1 0.0 1.1 1 0 0 1 1 1 1 Amnionless Stevor PF17410.2 KIK46774.1 - 0.0035 16.9 0.9 0.0052 16.4 0.9 1.3 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame DUF5305 PF17231.2 KIK46774.1 - 0.019 14.3 0.2 0.032 13.6 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF4836 PF16120.5 KIK46774.1 - 0.028 13.4 0.4 0.7 8.8 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4836) DUF4448 PF14610.6 KIK46774.1 - 0.029 14.1 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3951 PF13131.6 KIK46774.1 - 0.12 12.6 2.1 0.28 11.4 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) DUF4690 PF15756.5 KIK46774.1 - 0.12 13.0 3.2 0.12 13.0 0.8 2.2 2 0 0 2 2 2 0 Small Novel Rich in Cartilage DUF2615 PF11027.8 KIK46774.1 - 0.19 11.9 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) TMEM154 PF15102.6 KIK46774.1 - 0.57 10.1 4.3 0.14 12.0 0.4 2.1 2 1 0 2 2 2 0 TMEM154 protein family AAA_lid_2 PF17863.1 KIK46776.1 - 3.3 7.6 7.8 0.16 11.8 0.8 2.4 2 1 1 3 3 3 0 AAA lid domain BTB PF00651.31 KIK46779.1 - 1.4e-12 47.9 0.0 5.3e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain AAA_18 PF13238.6 KIK46779.1 - 0.073 13.6 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RhoGAP PF00620.27 KIK46781.1 - 5.1e-44 149.8 0.0 2e-43 147.8 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 KIK46781.1 - 1.4e-12 47.6 31.6 1.1e-07 31.9 9.2 3.4 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.22 KIK46781.1 - 1e-06 28.5 9.0 1e-06 28.5 9.0 4.0 3 1 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KIK46781.1 - 0.0055 17.0 3.5 0.0055 17.0 3.5 4.4 3 2 0 3 3 3 1 C1 domain DUF4407 PF14362.6 KIK46781.1 - 3.9 6.7 10.8 5.3 6.3 9.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TolA_bind_tri PF16331.5 KIK46781.1 - 4 7.6 13.0 3.6 7.7 5.8 2.7 2 0 0 2 2 2 0 TolA binding protein trimerisation YabA PF06156.13 KIK46781.1 - 4.5 8.0 7.4 0.5 11.0 1.1 2.7 2 1 1 3 3 3 0 Initiation control protein YabA DUF1201 PF06716.11 KIK46782.1 - 0.11 12.5 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) Herpes_UL33 PF03581.13 KIK46783.1 - 0.097 13.1 0.0 0.18 12.2 0.0 1.5 2 0 0 2 2 2 0 Herpesvirus UL33-like protein ELL PF10390.9 KIK46785.1 - 4.3e-06 26.4 0.2 4.3e-06 26.4 0.2 2.6 3 0 0 3 3 3 1 RNA polymerase II elongation factor ELL MDM31_MDM32 PF08118.11 KIK46787.1 - 2.5e-214 712.8 0.3 3e-214 712.6 0.3 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins 2-oxogl_dehyd_N PF16078.5 KIK46788.1 - 0.024 14.2 0.1 0.034 13.7 0.1 1.2 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus Sugar_tr PF00083.24 KIK46789.1 - 2.1e-95 320.2 14.6 4.9e-95 319.0 14.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK46789.1 - 9.5e-22 77.4 30.5 4.6e-11 42.2 6.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIK46789.1 - 0.00055 18.5 2.6 0.00055 18.5 2.6 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) F-box-like PF12937.7 KIK46790.1 - 3.3e-08 33.3 0.5 3e-07 30.2 0.4 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK46790.1 - 0.0036 17.2 0.1 0.17 11.8 0.0 2.8 2 1 0 2 2 2 1 F-box domain CT_A_B PF02626.15 KIK46791.1 - 4.6e-74 249.4 0.0 7.4e-74 248.7 0.0 1.3 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 KIK46791.1 - 1.5e-59 201.0 0.0 2.8e-59 200.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 KIK46791.1 - 7.9e-38 130.2 0.0 1.6e-37 129.3 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_N PF00289.22 KIK46791.1 - 1.8e-35 121.8 0.2 2.8e-34 118.0 0.1 2.4 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KIK46791.1 - 6.1e-32 109.9 0.0 1.2e-31 109.0 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 KIK46791.1 - 7.1e-09 35.5 0.0 1.3e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.22 KIK46791.1 - 4.9e-06 26.3 0.8 1.2e-05 25.0 0.8 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_5 PF13549.6 KIK46791.1 - 0.032 13.7 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp PF02222.22 KIK46791.1 - 0.062 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.11 KIK46791.1 - 0.17 11.5 0.0 0.73 9.4 0.0 2.1 1 1 0 1 1 1 0 RimK-like ATP-grasp domain DUF202 PF02656.15 KIK46792.1 - 4.5 7.8 6.4 0.36 11.3 1.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF202) LamB_YcsF PF03746.16 KIK46793.1 - 9.4e-81 271.0 0.0 1.1e-80 270.8 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family TMEM154 PF15102.6 KIK46794.1 - 0.0015 18.4 1.1 0.0015 18.4 1.1 1.5 2 0 0 2 2 2 1 TMEM154 protein family PHO4 PF01384.20 KIK46794.1 - 0.0016 17.6 0.6 0.0025 16.9 0.6 1.3 1 0 0 1 1 1 1 Phosphate transporter family DAG1 PF05454.11 KIK46794.1 - 0.0031 16.9 0.1 0.0042 16.5 0.1 1.2 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Alpha_GJ PF03229.13 KIK46794.1 - 0.0038 17.8 4.4 0.0038 17.8 4.4 1.9 2 0 0 2 2 2 1 Alphavirus glycoprotein J Glycophorin_A PF01102.18 KIK46794.1 - 0.06 13.6 0.9 0.11 12.7 0.9 1.4 1 0 0 1 1 1 0 Glycophorin A DUF5383 PF17355.2 KIK46794.1 - 0.08 13.3 0.0 0.08 13.3 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5383) DUF5305 PF17231.2 KIK46794.1 - 0.08 12.3 0.2 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF2062 PF09835.9 KIK46794.1 - 0.081 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) EphA2_TM PF14575.6 KIK46794.1 - 0.26 12.2 1.0 0.45 11.4 0.1 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 KIK46794.1 - 1 9.5 4.7 0.27 11.3 0.3 2.0 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Aldo_ket_red PF00248.21 KIK46796.1 - 5e-42 144.1 0.2 5.8e-40 137.3 0.2 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Beta_elim_lyase PF01212.21 KIK46796.1 - 0.044 13.1 0.1 0.095 12.0 0.1 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Dynamin_M PF01031.20 KIK46797.1 - 2.7e-29 102.3 0.0 5.9e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KIK46797.1 - 3.8e-27 95.4 0.0 7.8e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KIK46797.1 - 3e-11 43.3 0.2 1e-10 41.6 0.2 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIK46797.1 - 0.00018 21.6 0.7 0.0042 17.2 0.7 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KIK46797.1 - 0.00069 20.0 0.5 0.14 12.5 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_28 PF13521.6 KIK46797.1 - 0.13 12.6 2.0 0.17 12.1 0.1 2.3 3 0 0 3 3 3 0 AAA domain FBPase_2 PF06874.11 KIK46798.1 - 0.14 10.4 0.0 0.14 10.4 0.0 1.0 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase Polysacc_deac_1 PF01522.21 KIK46800.1 - 1.6e-25 89.4 0.0 3.8e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase AF-4 PF05110.13 KIK46800.1 - 1.8 6.6 6.1 2.2 6.3 6.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Amidase PF01425.21 KIK46802.1 - 5.7e-86 289.3 0.0 1.4e-85 288.0 0.0 1.6 1 1 0 1 1 1 1 Amidase Inositol_P PF00459.25 KIK46805.1 - 1.7e-46 158.9 0.1 2.7e-45 155.0 0.1 2.0 1 1 0 1 1 1 1 Inositol monophosphatase family DUF3612 PF12268.8 KIK46808.1 - 0.058 13.5 0.0 0.064 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) RicinB_lectin_2 PF14200.6 KIK46809.1 - 5.6e-07 30.2 0.8 4.5e-06 27.3 0.5 1.9 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like DBD_Tnp_Mut PF03108.15 KIK46809.1 - 0.017 15.1 0.1 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 MuDR family transposase Inhibitor_I66 PF16850.5 KIK46809.1 - 0.018 14.9 0.1 0.056 13.3 0.1 1.8 1 1 0 1 1 1 0 Peptidase inhibitor I66 MMR_HSR1 PF01926.23 KIK46812.1 - 2.4e-18 66.3 0.2 5.2e-15 55.5 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KIK46812.1 - 1.6e-09 37.5 0.1 4.9e-07 29.4 0.0 2.5 3 0 0 3 3 3 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KIK46812.1 - 2.2e-08 34.2 0.1 8e-08 32.4 0.1 1.9 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KIK46812.1 - 2.8e-05 23.8 0.0 0.0031 17.1 0.0 2.8 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KIK46812.1 - 0.00034 20.7 2.2 0.46 10.5 1.0 3.2 2 1 0 2 2 2 2 Dynamin family AIG1 PF04548.16 KIK46812.1 - 0.0015 17.9 0.4 0.018 14.4 0.1 2.2 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.6 KIK46812.1 - 0.0053 17.2 0.1 0.71 10.2 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain cobW PF02492.19 KIK46812.1 - 0.012 15.2 0.0 0.72 9.4 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KIK46812.1 - 0.014 15.6 0.1 8.5 6.6 0.0 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 KIK46812.1 - 0.015 14.3 0.1 0.091 11.7 0.1 2.2 1 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 KIK46812.1 - 0.018 14.5 0.1 3.5 7.1 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family THF_DHG_CYH_C PF02882.19 KIK46812.1 - 0.059 12.7 0.3 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AAA_18 PF13238.6 KIK46812.1 - 0.53 10.8 0.0 0.53 10.8 0.0 2.2 3 0 0 3 3 3 0 AAA domain adh_short_C2 PF13561.6 KIK46814.1 - 9.9e-64 215.1 0.6 1.4e-63 214.6 0.6 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK46814.1 - 1.4e-55 187.8 0.2 1.8e-55 187.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK46814.1 - 6.9e-14 52.1 0.5 1e-13 51.6 0.5 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KIK46814.1 - 0.00015 20.9 0.5 0.00021 20.4 0.5 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KIK46814.1 - 0.00065 19.2 0.2 0.0013 18.3 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK46814.1 - 0.023 14.1 0.1 0.047 13.1 0.1 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF5475 PF17569.2 KIK46814.1 - 0.15 12.4 0.1 0.28 11.5 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5475) adh_short_C2 PF13561.6 KIK46816.1 - 1.7e-63 214.3 2.0 2.9e-63 213.6 2.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK46816.1 - 5.6e-56 189.1 0.5 6.9e-56 188.8 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK46816.1 - 1.2e-14 54.7 0.8 2e-14 53.9 0.8 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK46816.1 - 0.0027 17.2 0.4 0.011 15.3 0.4 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK46816.1 - 0.037 13.4 0.1 0.063 12.7 0.1 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glyco_trans_2_3 PF13632.6 KIK46819.1 - 3.7e-55 186.9 0.2 3.7e-55 186.9 0.2 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KIK46819.1 - 5.4e-06 26.5 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIK46819.1 - 0.0042 16.9 0.0 0.014 15.2 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KIK46819.1 - 0.12 11.8 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 KIK46820.1 - 2.5e-54 184.2 0.1 2.5e-54 184.2 0.1 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KIK46820.1 - 0.00028 20.9 0.0 0.00055 19.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIK46820.1 - 0.0026 17.6 0.0 0.01 15.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KIK46820.1 - 0.021 14.3 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.21 KIK46821.1 - 6.2e-17 61.6 0.8 1.3e-16 60.6 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 UbiA PF01040.18 KIK46824.1 - 4.4e-46 157.2 16.5 5.5e-46 156.9 16.5 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF1708 PF08101.11 KIK46827.1 - 1e-23 84.3 0.0 9.7e-21 74.4 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1708) RhoGAP PF00620.27 KIK46827.1 - 0.011 15.6 0.0 0.031 14.1 0.0 1.7 2 0 0 2 2 2 0 RhoGAP domain Hydantoinase_A PF01968.18 KIK46828.1 - 4.1e-96 321.7 0.0 6.6e-96 321.0 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KIK46828.1 - 1.7e-57 194.0 0.0 1.9e-54 184.0 0.0 2.2 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region ABC2_membrane PF01061.24 KIK46829.1 - 1.4e-71 240.2 67.0 2.9e-37 128.2 23.4 3.4 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.12 KIK46829.1 - 4e-35 119.6 6.8 3e-27 94.3 0.2 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 KIK46829.1 - 7.9e-33 113.9 0.0 3.7e-15 56.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 KIK46829.1 - 5.4e-11 43.0 0.0 1.3e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KIK46829.1 - 1.1e-05 25.9 0.1 0.0083 16.5 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 KIK46829.1 - 1.1e-05 24.7 47.7 1.2e-05 24.6 22.7 2.9 2 1 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KIK46829.1 - 1.2e-05 25.2 0.1 0.00041 20.3 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KIK46829.1 - 1.4e-05 24.7 0.3 0.00079 19.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 KIK46829.1 - 5.7e-05 23.4 1.6 0.23 11.7 0.2 3.9 4 0 0 4 4 4 1 AAA domain NACHT PF05729.12 KIK46829.1 - 0.002 18.1 0.0 0.15 12.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.6 KIK46829.1 - 0.0021 17.9 2.8 2 8.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system dNK PF01712.19 KIK46829.1 - 0.0023 17.8 0.0 0.16 11.8 0.0 2.4 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_29 PF13555.6 KIK46829.1 - 0.0024 17.5 0.6 0.21 11.3 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KIK46829.1 - 0.0032 17.5 0.1 0.87 9.7 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KIK46829.1 - 0.0068 17.0 0.0 2.5 8.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KIK46829.1 - 0.0073 16.7 0.2 8.4 6.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 KIK46829.1 - 0.0095 15.9 0.8 0.11 12.6 0.3 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SMC_N PF02463.19 KIK46829.1 - 0.012 15.1 0.0 0.17 11.3 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 KIK46829.1 - 0.013 15.7 0.0 2.6 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIK46829.1 - 0.057 13.1 0.8 2.1 8.0 0.4 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KIK46829.1 - 0.062 13.5 0.3 0.51 10.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KIK46829.1 - 0.066 13.6 0.1 4.3 7.8 0.1 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK46829.1 - 0.093 13.1 0.0 6.8 7.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 KIK46829.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KIK46829.1 - 0.28 10.8 0.9 1.2 8.7 0.3 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain p450 PF00067.22 KIK46833.1 - 2.2e-64 217.9 0.0 2.6e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ACT_7 PF13840.6 KIK46835.1 - 0.0021 17.8 3.4 0.11 12.2 0.1 3.6 3 1 1 4 4 4 1 ACT domain NUC PF18510.1 KIK46835.1 - 0.02 15.4 1.1 8.7 6.8 0.0 3.7 2 2 1 4 4 4 0 Nuclease domain Pim PF16765.5 KIK46835.1 - 0.086 13.0 1.3 2.6 8.3 0.1 2.8 2 1 1 3 3 3 0 Pesticin immunity protein DUF406 PF04175.12 KIK46835.1 - 8.4 6.9 7.0 21 5.7 0.2 3.3 3 2 1 4 4 4 0 Protein of unknown function (DUF406) Ubiq_cyt_C_chap PF03981.12 KIK46836.1 - 2e-23 83.0 0.1 1.6e-13 50.9 0.0 3.0 3 0 0 3 3 3 2 Ubiquinol-cytochrome C chaperone Cep57_MT_bd PF06657.13 KIK46837.1 - 0.012 16.1 0.9 7.3 7.1 0.1 2.6 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Ran_BP1 PF00638.18 KIK46837.1 - 0.012 15.8 0.2 0.016 15.4 0.2 1.2 1 0 0 1 1 1 0 RanBP1 domain RelB_N PF18506.1 KIK46837.1 - 0.14 12.0 0.7 19 5.1 0.1 2.3 2 0 0 2 2 2 0 RelB Antitoxin alpha helical domain DUF3967 PF13152.6 KIK46837.1 - 0.19 11.5 2.0 13 5.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3967) DUF327 PF03885.13 KIK46837.1 - 0.49 10.4 4.3 9.1 6.2 0.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF327) Cadherin-like PF12733.7 KIK46837.1 - 4.7 7.8 8.1 3.5 8.2 5.0 2.2 1 1 1 2 2 2 0 Cadherin-like beta sandwich domain Kdo PF06293.14 KIK46840.1 - 8.4e-10 38.3 0.0 9.6e-08 31.6 0.0 2.1 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK46840.1 - 2.4e-07 30.9 0.0 9.5e-06 25.7 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK46840.1 - 1.4e-06 28.1 0.0 2.3e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KIK46840.1 - 4e-06 26.4 0.0 4.3e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain EcKinase PF02958.20 KIK46840.1 - 1.8e-05 24.2 0.0 2.2e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KIK46840.1 - 0.0018 17.9 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KIK46840.1 - 0.015 14.1 0.3 0.021 13.6 0.3 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 KIK46840.1 - 0.075 12.3 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Oxidored_FMN PF00724.20 KIK46841.1 - 1.9e-45 155.6 0.0 2.4e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KIK46841.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) MR_MLE_C PF13378.6 KIK46841.1 - 0.02 14.5 0.0 0.38 10.3 0.0 2.4 2 0 0 2 2 2 0 Enolase C-terminal domain-like Peptidase_C12 PF01088.21 KIK46842.1 - 1.9e-52 178.1 0.0 2.3e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 p450 PF00067.22 KIK46843.1 - 7.1e-59 199.8 0.0 1e-58 199.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GIDA PF01134.22 KIK46844.1 - 3.7e-157 523.4 0.0 6.1e-157 522.7 0.0 1.3 2 0 0 2 2 2 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KIK46844.1 - 4.2e-62 210.1 0.0 6.5e-62 209.5 0.0 1.3 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 KIK46844.1 - 3.3e-06 26.7 0.8 7e-06 25.7 0.8 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK46844.1 - 6.5e-06 25.6 1.1 6.2e-05 22.4 0.9 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIK46844.1 - 0.0039 16.3 2.7 0.0058 15.8 1.8 1.7 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KIK46844.1 - 0.0052 16.1 0.2 0.011 15.0 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KIK46844.1 - 0.019 13.7 2.4 0.58 8.8 0.6 2.6 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox PF00070.27 KIK46844.1 - 0.055 14.0 0.2 0.13 12.8 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK46844.1 - 0.076 12.3 0.0 0.27 10.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK46844.1 - 0.3 11.3 1.7 1.5 9.1 1.5 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK46844.1 - 0.51 9.9 5.9 9 5.8 2.5 2.9 3 1 0 3 3 3 0 FAD dependent oxidoreductase IFR3_antag PF14754.6 KIK46845.1 - 0.047 12.9 3.8 0.074 12.2 3.8 1.2 1 0 0 1 1 1 0 Papain-like auto-proteinase FYVE_2 PF02318.16 KIK46845.1 - 5 7.4 14.3 0.81 9.9 0.7 2.4 2 1 0 2 2 2 0 FYVE-type zinc finger IBR PF01485.21 KIK46845.1 - 5.5 7.3 16.5 6.8 7.0 9.9 3.3 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain SEP PF08059.13 KIK46847.1 - 6e-23 81.2 0.2 1.8e-22 79.7 0.0 2.0 3 0 0 3 3 3 1 SEP domain UBX PF00789.20 KIK46847.1 - 1.2e-13 51.0 0.0 2e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 UBX domain PCI PF01399.27 KIK46848.1 - 1.1e-08 35.6 0.2 0.00032 21.2 0.0 3.8 3 0 0 3 3 3 3 PCI domain Ion_trans PF00520.31 KIK46849.1 - 5.7e-122 405.6 93.5 1.9e-37 128.8 17.6 5.2 5 0 0 5 5 5 5 Ion transport protein Methyltransf_16 PF10294.9 KIK46850.1 - 2.7e-15 56.5 0.0 3.4e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase GidB PF02527.15 KIK46850.1 - 0.0004 19.8 0.0 0.0006 19.2 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_25 PF13649.6 KIK46850.1 - 0.12 13.1 0.0 0.41 11.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Pmp3 PF01679.17 KIK46851.1 - 4.6e-21 74.7 10.4 5.9e-21 74.4 10.4 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Sensor PF13796.6 KIK46851.1 - 0.015 15.3 0.1 0.019 15.0 0.1 1.2 1 0 0 1 1 1 0 Putative sensor ENTH PF01417.20 KIK46852.1 - 3.3e-50 169.3 0.0 5.4e-50 168.6 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KIK46852.1 - 9.6e-05 21.5 0.0 9.6e-05 21.5 0.0 2.1 2 0 0 2 2 2 1 ANTH domain Thioredoxin_11 PF18078.1 KIK46852.1 - 8.4 6.5 14.2 17 5.6 12.4 2.2 2 0 0 2 2 2 0 Thioredoxin-like SNTX domain F-box-like PF12937.7 KIK46853.1 - 0.016 15.1 0.0 0.045 13.6 0.0 1.9 1 0 0 1 1 1 0 F-box-like HLH PF00010.26 KIK46854.1 - 1.8e-11 43.8 0.0 5.3e-11 42.3 0.0 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain YL1 PF05764.13 KIK46854.1 - 0.011 15.9 2.1 0.038 14.1 2.1 1.9 1 0 0 1 1 1 0 YL1 nuclear protein Prefoldin PF02996.17 KIK46858.1 - 1.7e-29 102.2 3.4 2.3e-29 101.7 3.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KIK46858.1 - 0.0003 20.7 8.7 0.00097 19.1 1.5 2.3 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.6 KIK46858.1 - 0.00098 19.1 0.9 0.0024 17.9 0.9 1.7 1 1 0 1 1 1 1 Prefoldin subunit TMF_TATA_bd PF12325.8 KIK46858.1 - 0.0034 17.6 5.0 0.084 13.1 0.2 2.4 2 1 0 2 2 2 1 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.22 KIK46858.1 - 0.0073 16.5 3.4 1.3 9.2 0.4 2.3 2 0 0 2 2 2 2 Seryl-tRNA synthetase N-terminal domain XkdW PF09636.10 KIK46858.1 - 0.0078 16.3 2.2 0.046 13.8 0.4 2.1 2 0 0 2 2 2 1 XkdW protein Med30 PF11315.8 KIK46858.1 - 0.009 16.2 6.0 0.11 12.7 4.0 2.1 1 1 0 1 1 1 1 Mediator complex subunit 30 TACC_C PF05010.14 KIK46858.1 - 0.01 15.7 5.4 0.19 11.5 0.3 2.0 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF1664 PF07889.12 KIK46858.1 - 0.011 15.7 6.2 1.1 9.2 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KIK46858.1 - 0.012 15.8 8.2 1.2 9.3 8.2 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CLZ PF16526.5 KIK46858.1 - 0.012 15.9 6.9 0.86 10.0 1.4 2.8 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AIP3 PF03915.13 KIK46858.1 - 0.019 14.1 4.8 0.023 13.8 4.8 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 Baculo_PEP_C PF04513.12 KIK46858.1 - 0.02 15.0 3.8 0.76 9.8 0.4 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.9 KIK46858.1 - 0.022 14.8 6.4 1.1 9.2 0.6 2.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KIK46858.1 - 0.047 12.6 10.0 0.098 11.5 0.7 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein COG2 PF06148.11 KIK46858.1 - 0.087 12.9 4.8 3.2 7.8 1.4 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.11 KIK46858.1 - 0.1 13.0 3.5 8.5 6.9 0.1 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Zein-binding PF04576.15 KIK46858.1 - 0.13 12.6 4.6 0.57 10.5 0.9 2.2 2 0 0 2 2 2 0 Zein-binding EAP30 PF04157.16 KIK46858.1 - 0.15 11.3 3.7 0.99 8.6 0.6 2.0 2 0 0 2 2 2 0 EAP30/Vps36 family XhlA PF10779.9 KIK46858.1 - 0.24 11.6 1.7 20 5.5 0.1 2.4 2 0 0 2 2 2 0 Haemolysin XhlA Filament PF00038.21 KIK46858.1 - 0.31 10.6 11.1 3.8 7.0 11.2 1.9 1 1 0 1 1 1 0 Intermediate filament protein Sec2p PF06428.11 KIK46858.1 - 0.43 10.6 10.5 0.63 10.0 3.1 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p ApoO PF09769.9 KIK46858.1 - 0.95 9.4 4.3 14 5.7 0.1 2.3 2 1 0 2 2 2 0 Apolipoprotein O UPF0449 PF15136.6 KIK46858.1 - 0.98 9.9 6.6 8.7 6.9 1.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF16 PF01519.16 KIK46858.1 - 1 9.9 7.6 1.1 9.8 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 RasGAP_C PF03836.15 KIK46858.1 - 1.1 9.4 12.4 0.97 9.6 0.5 2.1 1 1 1 2 2 2 0 RasGAP C-terminus Exonuc_VII_L PF02601.15 KIK46858.1 - 1.9 8.0 7.8 5.1 6.6 7.8 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit GIT_CC PF16559.5 KIK46858.1 - 2.7 7.9 13.5 1 9.3 4.1 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.12 KIK46858.1 - 2.8 8.6 9.1 12 6.6 0.6 2.4 2 0 0 2 2 2 0 SlyX DivIC PF04977.15 KIK46858.1 - 4.9 7.0 8.3 0.3 10.9 0.5 2.5 2 1 0 2 2 2 0 Septum formation initiator DUF2347 PF09804.9 KIK46859.1 - 2.6e-46 158.5 0.0 3.7e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 KIK46859.1 - 1.7e-05 23.7 0.0 1.2 7.7 0.0 3.1 2 1 0 3 3 3 3 Transport protein Avl9 SPA PF08616.10 KIK46859.1 - 0.062 13.3 0.0 0.24 11.3 0.0 1.9 1 1 0 1 1 1 0 Stabilization of polarity axis PIN_4 PF13638.6 KIK46861.1 - 4.9e-07 30.1 0.0 7.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 PIN domain PI-PLC-X PF00388.19 KIK46863.1 - 1.3e-34 118.8 0.0 7.5e-34 116.4 0.0 2.2 2 1 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KIK46863.1 - 2.4e-31 108.4 0.0 4.9e-31 107.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KIK46863.1 - 0.00017 21.8 0.0 0.00033 20.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain MAGE PF01454.19 KIK46864.1 - 2.5e-49 167.9 0.1 2.5e-49 167.9 0.1 1.5 2 0 0 2 2 2 1 MAGE family Nucleo_P87 PF07267.11 KIK46864.1 - 0.77 8.5 5.0 1.6 7.5 5.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4820 PF16091.5 KIK46864.1 - 1.8 7.9 5.5 4 6.7 5.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Sugar_tr PF00083.24 KIK46865.1 - 2.4e-125 418.9 27.7 2.8e-125 418.7 27.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK46865.1 - 1.3e-20 73.6 45.8 1.7e-13 50.3 19.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Adenylsucc_synt PF00709.21 KIK46866.1 - 0.19 10.6 0.0 0.24 10.3 0.0 1.0 1 0 0 1 1 1 0 Adenylosuccinate synthetase KDZ PF18758.1 KIK46869.1 - 1.2e-28 100.2 5.1 1.2e-15 57.7 0.0 2.3 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK46869.1 - 4.9e-17 62.0 0.3 2.1e-16 60.0 0.3 2.1 1 1 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK46869.1 - 0.0033 17.6 0.0 0.013 15.6 0.0 2.0 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Helitron_like_N PF14214.6 KIK46873.1 - 7.3e-25 88.3 0.0 1.3e-24 87.5 0.0 1.4 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_integrase PF00589.22 KIK46874.1 - 0.008 16.0 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family ZapB PF06005.12 KIK46878.1 - 0.12 12.8 0.5 0.2 12.1 0.5 1.3 1 0 0 1 1 1 0 Cell division protein ZapB VirB7 PF17413.2 KIK46879.1 - 0.061 12.6 10.0 2.8 7.3 0.1 4.9 4 1 2 6 6 6 0 Outer membrane lipoprotein virB7 Plavaka PF18759.1 KIK46880.1 - 1e-40 140.0 0.0 1.6e-40 139.4 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase Noggin PF05806.12 KIK46881.1 - 0.0071 16.3 0.0 0.0095 15.9 0.0 1.1 1 0 0 1 1 1 1 Noggin HMGL-like PF00682.19 KIK46882.1 - 5.4e-79 265.5 0.2 8.2e-79 264.9 0.2 1.3 1 0 0 1 1 1 1 HMGL-like Collagen PF01391.18 KIK46882.1 - 0.032 14.0 1.0 0.055 13.2 1.0 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Ribosomal_S13 PF00416.22 KIK46884.1 - 1e-55 187.5 2.3 1.2e-55 187.3 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KIK46884.1 - 0.017 13.9 0.0 0.019 13.7 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF2746 PF10874.8 KIK46884.1 - 0.051 14.0 0.0 0.095 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) CLASP_N PF12348.8 KIK46885.1 - 3.8e-21 75.7 0.0 4.2e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 CLASP N terminal Ribosomal_L34 PF00468.17 KIK46887.1 - 1.5e-18 66.5 10.8 2.4e-18 65.8 10.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 CAP_GLY PF01302.25 KIK46888.1 - 2.4e-18 65.9 1.5 4e-18 65.2 1.5 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF4201 PF13870.6 KIK46888.1 - 0.018 14.8 0.6 0.018 14.8 0.6 7.1 3 3 1 6 6 6 0 Domain of unknown function (DUF4201) Retrotrans_gag PF03732.17 KIK46888.1 - 0.27 11.5 8.2 1.4 9.2 0.1 4.6 4 0 0 4 4 4 0 Retrotransposon gag protein Fez1 PF06818.15 KIK46888.1 - 0.91 9.9 80.3 0.31 11.5 13.8 5.7 1 1 5 6 6 6 0 Fez1 DUF547 PF04784.14 KIK46888.1 - 1.3 9.1 4.7 2.9 8.0 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function, DUF547 zf-CCHC PF00098.23 KIK46888.1 - 3.2 8.0 9.3 3.7 7.8 4.8 2.3 2 0 0 2 2 2 0 Zinc knuckle CLIP1_ZNF PF16641.5 KIK46888.1 - 5.3 7.0 18.9 0.24 11.3 3.5 2.8 3 0 0 3 3 3 0 CLIP1 zinc knuckle zf-CCHC_4 PF14392.6 KIK46888.1 - 6.8 6.5 7.3 6.6 6.6 0.3 2.7 2 0 0 2 2 2 0 Zinc knuckle NTP_transferase PF00483.23 KIK46890.1 - 3.6e-08 33.3 0.0 8.1e-08 32.1 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KIK46890.1 - 7.8e-07 29.6 0.0 1e-06 29.2 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 KIK46890.1 - 8.4e-05 22.1 2.7 0.29 10.9 0.3 3.0 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 KIK46890.1 - 0.0048 15.1 1.1 0.0068 14.6 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 KIK46890.1 - 3 7.7 5.6 1.7 8.5 1.7 2.4 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Pkinase PF00069.25 KIK46891.1 - 6.9e-65 219.0 0.0 8e-65 218.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK46891.1 - 2e-48 165.0 0.0 2.5e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK46891.1 - 5.6e-07 28.7 0.0 8.8e-07 28.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIK46891.1 - 2.9e-05 23.5 0.0 5.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIK46891.1 - 0.00014 21.9 0.0 0.25 11.2 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK46891.1 - 0.0038 16.2 0.0 0.021 13.8 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 KIK46891.1 - 0.0068 16.0 0.0 0.25 10.9 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KIK46891.1 - 0.05 13.0 0.0 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APS_kinase PF01583.20 KIK46893.1 - 6.8e-70 234.0 0.0 8.2e-70 233.8 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 KIK46893.1 - 0.00027 21.5 0.0 0.00057 20.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIK46893.1 - 0.0011 19.2 0.0 0.002 18.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIK46893.1 - 0.026 14.3 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain KTI12 PF08433.10 KIK46893.1 - 0.038 13.4 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Cpn60_TCP1 PF00118.24 KIK46894.1 - 9e-145 483.0 15.6 1e-144 482.9 15.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 KIK46894.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Peptidase_C15 PF01470.17 KIK46895.1 - 4e-06 27.1 0.0 0.0017 18.6 0.0 2.8 3 0 0 3 3 3 2 Pyroglutamyl peptidase MgsA_C PF12002.8 KIK46897.1 - 4.7e-53 179.5 0.1 9.7e-53 178.5 0.0 1.5 2 0 0 2 2 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KIK46897.1 - 3.9e-18 65.6 0.6 8.1e-18 64.5 0.6 1.5 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KIK46897.1 - 7.1e-17 62.1 0.0 1.5e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KIK46897.1 - 1.2e-14 54.4 0.0 1.9e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KIK46897.1 - 9e-09 35.9 0.4 0.0015 19.0 0.0 2.8 1 1 1 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 KIK46897.1 - 1.2e-08 35.1 0.0 7.2e-08 32.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KIK46897.1 - 1.5e-06 28.0 0.0 0.00011 21.9 0.0 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 KIK46897.1 - 2.7e-05 24.4 0.1 0.00022 21.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KIK46897.1 - 2.8e-05 24.2 0.0 5.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KIK46897.1 - 3e-05 23.5 0.2 0.13 11.6 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KIK46897.1 - 0.00023 21.1 0.0 0.0015 18.4 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 KIK46897.1 - 0.00028 21.0 0.0 0.00058 20.0 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.6 KIK46897.1 - 0.00028 21.4 0.0 0.00048 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KIK46897.1 - 0.0029 17.4 0.0 0.006 16.4 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KIK46897.1 - 0.003 17.9 0.0 0.0068 16.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 KIK46897.1 - 0.003 17.8 0.0 0.0053 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIK46897.1 - 0.0034 17.3 0.0 1.3 8.9 0.0 2.2 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 KIK46897.1 - 0.0035 17.3 0.0 0.0064 16.4 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_2 PF07724.14 KIK46897.1 - 0.005 17.0 0.0 0.0091 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ABC_tran PF00005.27 KIK46897.1 - 0.0054 17.3 0.0 0.022 15.2 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_25 PF13481.6 KIK46897.1 - 0.0092 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KIK46897.1 - 0.017 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 KIK46897.1 - 0.018 15.2 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase DNA_pol3_delta2 PF13177.6 KIK46897.1 - 0.026 14.3 0.0 0.51 10.1 0.0 2.1 1 1 1 2 2 2 0 DNA polymerase III, delta subunit AAA_33 PF13671.6 KIK46897.1 - 0.03 14.5 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KIK46897.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KIK46897.1 - 0.11 11.7 0.0 0.49 9.5 0.0 1.8 1 1 1 2 2 2 0 NB-ARC domain NACHT PF05729.12 KIK46897.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 KIK46897.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AraC_N PF06719.13 KIK46897.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus zf-WRNIP1_ubi PF18279.1 KIK46897.1 - 0.38 11.5 2.0 0.59 10.9 0.1 2.4 2 0 0 2 2 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain OPT PF03169.15 KIK46898.1 - 1.1e-156 523.1 46.7 1.2e-156 522.9 46.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3180 PF11377.8 KIK46898.1 - 0.56 10.3 8.5 3.9 7.6 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) DUF2254 PF10011.9 KIK46898.1 - 2.6 6.8 5.5 0.72 8.6 1.7 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) TRP PF06011.12 KIK46899.1 - 2.5e-75 253.8 26.8 4e-75 253.2 26.8 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KIK46899.1 - 6.6e-29 101.0 0.2 1e-28 100.4 0.2 1.3 1 0 0 1 1 1 1 ML-like domain Melibiase_C PF17801.1 KIK46899.1 - 0.16 12.1 0.0 0.46 10.6 0.0 1.8 1 0 0 1 1 1 0 Alpha galactosidase C-terminal beta sandwich domain Corona_nucleoca PF00937.18 KIK46899.1 - 9.1 5.2 9.9 15 4.5 9.9 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Rubredoxin_2 PF18073.1 KIK46900.1 - 0.43 10.4 3.0 0.59 9.9 3.0 1.2 1 0 0 1 1 1 0 Rubredoxin metal binding domain Rad10 PF03834.14 KIK46902.1 - 7e-47 158.2 0.1 1.1e-46 157.5 0.1 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 KIK46902.1 - 5.3e-08 33.4 0.4 1.1e-07 32.3 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.7 KIK46902.1 - 0.041 14.0 0.0 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif Amidohydro_1 PF01979.20 KIK46903.1 - 2.1e-16 60.2 0.1 8.7e-14 51.6 0.0 3.1 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KIK46903.1 - 1e-15 58.2 3.0 2.2e-10 40.6 0.1 3.9 4 0 0 4 4 4 3 Amidohydrolase family Hist_deacetyl PF00850.19 KIK46904.1 - 4.6e-87 292.4 0.0 6.2e-87 291.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 KIK46904.1 - 3.1e-41 141.2 0.0 4.3e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Arb2 domain Tetraspanin PF00335.20 KIK46905.1 - 1.8e-05 24.6 8.7 1.8e-05 24.6 8.7 2.0 1 1 1 2 2 2 1 Tetraspanin family PgaD PF13994.6 KIK46905.1 - 0.012 15.6 0.8 0.012 15.6 0.8 2.0 1 1 1 2 2 2 0 PgaD-like protein COX15-CtaA PF02628.15 KIK46905.1 - 0.023 13.7 1.9 0.032 13.3 1.9 1.1 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein DUF5453 PF17534.2 KIK46905.1 - 0.19 11.7 4.7 0.3 11.0 4.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5453) DUF3671 PF12420.8 KIK46905.1 - 1.2 9.3 7.5 0.35 11.0 3.2 2.0 1 1 1 2 2 2 0 Protein of unknown function Ninjurin PF04923.12 KIK46905.1 - 1.3 8.9 5.1 1.4 8.9 3.3 1.8 1 1 1 2 2 2 0 Ninjurin DUF1746 PF08508.10 KIK46906.1 - 3.5e-06 27.3 1.1 6.9e-06 26.4 1.1 1.5 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) CX9C PF16860.5 KIK46907.1 - 3.2e-05 23.8 1.4 0.0066 16.4 0.5 2.2 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 KIK46907.1 - 0.00013 22.1 2.5 0.00047 20.3 2.5 1.7 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 KIK46907.1 - 0.073 13.4 1.4 0.16 12.4 1.4 1.5 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) GCK PF07802.11 KIK46907.1 - 0.25 11.8 3.5 0.5 10.8 1.9 1.9 1 1 1 2 2 2 0 GCK domain Yip1 PF04893.17 KIK46909.1 - 2.3e-07 30.7 11.6 3.5e-07 30.1 11.6 1.3 1 0 0 1 1 1 1 Yip1 domain DUF2070 PF09843.9 KIK46909.1 - 6.6 4.9 7.0 8.6 4.5 7.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ribosomal_S8e PF01201.22 KIK46910.1 - 4.6e-48 162.9 1.4 1.5e-47 161.2 1.4 1.8 1 1 0 1 1 1 1 Ribosomal protein S8e DUF1490 PF07371.12 KIK46910.1 - 0.14 12.2 1.3 0.33 11.1 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1490) DUF1168 PF06658.12 KIK46911.1 - 7.2e-38 129.5 17.3 1e-37 129.0 17.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Lyase_catalyt PF09093.11 KIK46911.1 - 0.13 11.4 0.1 0.26 10.4 0.0 1.4 1 1 0 1 1 1 0 Lyase, catalytic tRNA_synt_1c_R2 PF04557.15 KIK46911.1 - 0.77 10.7 9.2 0.7 10.9 7.5 1.8 1 1 1 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 F-box-like PF12937.7 KIK46915.1 - 1.8e-08 34.1 0.3 8.6e-08 32.0 0.2 2.2 2 0 0 2 2 2 1 F-box-like Ank_4 PF13637.6 KIK46916.1 - 1.3e-08 35.2 0.1 8.1e-07 29.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KIK46916.1 - 0.00021 21.6 0.0 0.0011 19.4 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KIK46916.1 - 0.00023 21.7 0.1 0.00049 20.6 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIK46916.1 - 0.011 16.1 0.1 0.044 14.1 0.1 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Sybindin PF04099.12 KIK46918.1 - 1.2e-21 77.2 0.0 1.5e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family SNF2_N PF00176.23 KIK46919.1 - 7.3e-60 202.5 0.0 1.4e-59 201.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK46919.1 - 2.5e-17 63.2 0.1 8.6e-17 61.5 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK46919.1 - 1.8e-11 44.3 0.0 5.2e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KIK46919.1 - 3.4e-05 23.2 0.3 7.3e-05 22.1 0.3 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HHH_3 PF12836.7 KIK46919.1 - 0.00033 20.9 0.0 0.00089 19.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Mito_carr PF00153.27 KIK46920.1 - 2.7e-12 46.4 0.0 6.8e-06 25.9 0.0 2.5 2 1 0 2 2 2 2 Mitochondrial carrier protein DUF1761 PF08570.10 KIK46920.1 - 0.1 12.9 1.6 0.16 12.2 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) GLTSCR1 PF15249.6 KIK46921.1 - 6e-27 94.1 0.2 9.3e-27 93.5 0.2 1.3 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein CCDC-167 PF15188.6 KIK46921.1 - 0.23 11.8 0.6 0.41 11.0 0.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 TPR_1 PF00515.28 KIK46922.1 - 5e-29 98.9 12.3 0.00021 21.0 0.0 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 KIK46922.1 - 4.7e-24 82.6 13.2 3.1e-05 23.8 0.0 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 KIK46922.1 - 3.4e-23 79.8 20.0 0.0014 18.5 0.1 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat ANAPC8 PF04049.13 KIK46922.1 - 5e-18 65.5 0.1 3.5e-17 62.8 0.1 2.1 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_14 PF13428.6 KIK46922.1 - 1.3e-15 56.7 15.6 0.0062 17.3 0.1 7.2 5 2 2 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 KIK46922.1 - 1.1e-14 54.5 23.7 4.2e-05 23.8 2.2 6.1 3 1 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 KIK46922.1 - 2.9e-13 49.3 4.5 1.1e-06 28.2 0.5 4.7 2 2 2 4 4 4 3 TPR repeat TPR_16 PF13432.6 KIK46922.1 - 1.1e-11 45.2 14.8 3.7e-06 27.5 2.5 5.5 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK46922.1 - 1.4e-11 44.0 4.9 0.48 10.9 0.1 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIK46922.1 - 2.5e-09 36.5 18.6 0.23 11.5 0.1 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIK46922.1 - 7.1e-08 32.9 12.6 0.035 14.6 0.3 6.2 5 1 3 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 KIK46922.1 - 4.4e-06 26.8 11.1 0.011 15.9 3.4 4.3 2 1 1 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.10 KIK46922.1 - 0.00028 20.0 0.2 0.041 12.9 0.0 3.0 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 KIK46922.1 - 0.001 18.9 15.4 2.4 8.1 0.7 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 KIK46922.1 - 0.0011 18.2 7.5 0.044 13.0 4.0 2.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIK46922.1 - 0.0029 18.1 14.1 34 5.4 0.1 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK46922.1 - 0.18 12.1 18.1 0.24 11.6 1.2 4.8 3 1 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 KIK46922.1 - 0.25 11.4 3.5 3.1 7.9 0.1 3.1 2 1 1 3 3 2 0 Domain of Unknown Function (DUF3856) RPN7 PF10602.9 KIK46922.1 - 2 8.1 5.5 18 5.0 0.0 3.7 2 2 2 4 4 4 0 26S proteasome subunit RPN7 Alg14 PF08660.11 KIK46923.1 - 2.6e-56 190.3 0.0 3.9e-56 189.7 0.0 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like YjeF_N PF03853.15 KIK46923.1 - 0.043 13.7 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus zf-CCCH PF00642.24 KIK46925.1 - 3.4e-14 52.3 16.3 4.7e-07 29.6 3.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KIK46925.1 - 0.0063 17.2 1.8 1.6 9.4 0.1 2.3 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KIK46925.1 - 0.0065 16.5 3.3 0.0065 16.5 3.3 2.5 2 0 0 2 2 2 2 Zinc finger domain RRM_1 PF00076.22 KIK46925.1 - 0.009 15.8 0.0 0.024 14.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_3 PF15663.5 KIK46925.1 - 0.014 15.6 4.6 0.28 11.4 0.4 2.2 2 0 0 2 2 2 0 Zinc-finger containing family Zn_clus PF00172.18 KIK46926.1 - 1.4e-06 28.3 6.2 3.6e-06 27.0 6.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_A_bac PF01000.26 KIK46928.1 - 1.1e-29 103.0 0.0 1.9e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KIK46928.1 - 7.8e-17 60.5 0.0 1.2e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.16 KIK46928.1 - 0.13 12.0 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF22 ADH_zinc_N PF00107.26 KIK46929.1 - 2.8e-30 105.0 0.3 4.1e-30 104.4 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK46929.1 - 1.2e-13 52.2 0.0 2.1e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK46929.1 - 4.3e-05 23.3 0.0 0.00014 21.7 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KIK46929.1 - 0.034 13.4 0.6 0.05 12.9 0.6 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3942 PF13078.6 KIK46929.1 - 0.054 13.8 0.0 14 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3942) DUF913 PF06025.12 KIK46930.1 - 3.1e-99 332.4 0.0 3.1e-99 332.4 0.0 5.9 5 1 0 5 5 5 1 Domain of Unknown Function (DUF913) HECT PF00632.25 KIK46930.1 - 1e-91 307.6 0.0 2e-91 306.7 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 KIK46930.1 - 1.4e-75 255.0 5.3 1.4e-75 255.0 5.3 2.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) UBM PF14377.6 KIK46930.1 - 3e-27 93.2 19.6 8.8e-11 40.9 0.7 3.8 3 0 0 3 3 3 3 Ubiquitin binding region UBA PF00627.31 KIK46930.1 - 1.3e-10 41.0 1.1 2.2e-10 40.2 0.1 2.1 2 0 0 2 2 2 1 UBA/TS-N domain PC4 PF02229.16 KIK46931.1 - 4.5e-24 83.8 0.4 4.5e-24 83.8 0.4 1.6 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) ABC1 PF03109.16 KIK46932.1 - 8.8e-33 113.0 0.0 1.6e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 KIK46932.1 - 9.6e-06 25.3 0.1 0.00039 20.1 0.0 2.2 2 0 0 2 2 2 1 RIO1 family HTH_IclR PF09339.10 KIK46932.1 - 0.011 15.5 0.2 0.025 14.4 0.2 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain Pkinase PF00069.25 KIK46932.1 - 0.015 14.7 1.1 0.17 11.2 0.0 2.4 3 0 0 3 3 3 0 Protein kinase domain Rad9 PF04139.13 KIK46933.1 - 4e-26 92.0 0.0 5.7e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Rad9 NAD_binding_9 PF13454.6 KIK46934.1 - 0.0007 19.6 0.0 0.0031 17.5 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KIK46934.1 - 0.061 12.6 0.0 15 4.7 0.0 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PH PF00169.29 KIK46935.1 - 0.0051 17.3 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 PH domain DUF760 PF05542.11 KIK46935.1 - 0.16 12.4 1.5 0.46 10.9 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF760) Thiamine_BP PF01910.17 KIK46935.1 - 0.34 10.8 1.8 3.1 7.8 0.3 2.8 2 1 0 2 2 2 0 Thiamine-binding protein REF PF05755.12 KIK46935.1 - 0.4 10.5 1.6 5 6.9 0.2 2.4 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) ParB PF08775.10 KIK46935.1 - 1.2 9.6 8.9 0.84 10.1 0.3 3.3 2 1 1 3 3 3 0 ParB family DUF3926 PF13080.6 KIK46935.1 - 2.5 8.1 0.0 2.5 8.1 0.0 3.3 4 1 1 5 5 5 0 Protein of unknown function (DUF3926) YojJ PF10372.9 KIK46935.1 - 3.4 7.8 5.9 0.74 9.9 0.4 2.9 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus CorA PF01544.18 KIK46935.1 - 3.5 6.9 12.6 0.025 13.9 1.4 2.4 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein LPP PF04728.13 KIK46935.1 - 4.3 7.8 7.1 3.6 8.1 0.3 4.0 3 1 1 4 4 4 0 Lipoprotein leucine-zipper Myticin-prepro PF10690.9 KIK46937.1 - 0.24 11.7 7.2 0.27 11.5 7.2 1.0 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel Luteo_Vpg PF01659.16 KIK46939.1 - 0.052 13.9 0.1 0.076 13.4 0.1 1.3 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein Tim17 PF02466.19 KIK46940.1 - 1.1e-30 106.2 7.9 1.4e-30 105.9 7.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ALAD PF00490.21 KIK46941.1 - 6.8e-120 400.0 0.0 8.4e-120 399.7 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase zf-4CXXC_R1 PF10497.9 KIK46942.1 - 1.6e-15 57.1 13.5 6e-14 52.1 13.5 2.6 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 WSD PF15613.6 KIK46942.1 - 0.0038 17.7 4.6 0.0038 17.7 4.6 2.9 3 1 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif CBFD_NFYB_HMF PF00808.23 KIK46946.1 - 3e-13 49.8 1.0 4.8e-13 49.2 1.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK46946.1 - 1.9e-10 41.2 0.9 1.9e-10 41.2 0.9 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KIK46946.1 - 0.0035 17.4 0.1 0.0051 16.9 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold DisA-linker PF10635.9 KIK46946.1 - 0.017 14.9 0.3 0.028 14.2 0.3 1.3 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region Bromo_TP PF07524.13 KIK46946.1 - 0.019 14.9 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-S PF15630.6 KIK46946.1 - 0.11 12.9 0.2 0.22 11.9 0.2 1.6 1 1 0 1 1 1 0 CENP-S protein DNA_primase_S PF01896.19 KIK46947.1 - 2.2e-48 164.6 0.0 3.6e-48 163.9 0.0 1.4 1 0 0 1 1 1 1 DNA primase small subunit Myc_target_1 PF15179.6 KIK46948.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Myc target protein 1 Man-6-P_recep PF02157.15 KIK46948.1 - 0.28 10.2 0.1 0.41 9.7 0.1 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate receptor NICE-3 PF07406.11 KIK46950.1 - 0.22 11.5 0.1 0.42 10.6 0.1 1.4 1 0 0 1 1 1 0 NICE-3 protein RCDG1 PF15725.5 KIK46950.1 - 9.6 6.7 13.6 1.7e+02 2.7 13.6 2.7 1 1 0 1 1 1 0 Renal cancer differentiation gene 1 protein p450 PF00067.22 KIK46951.1 - 4.6e-79 266.3 0.0 7.4e-79 265.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 GST_N_2 PF13409.6 KIK46953.1 - 5.1e-20 71.5 0.0 1.1e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK46953.1 - 2.3e-14 53.2 0.0 1.5e-13 50.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIK46953.1 - 2.2e-09 37.4 0.0 4.3e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK46953.1 - 6.3e-05 23.1 0.0 0.00018 21.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIK46953.1 - 0.00013 22.3 0.0 0.0032 17.8 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KIK46953.1 - 0.045 13.5 0.0 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain ubiquitin PF00240.23 KIK46954.1 - 8.2e-17 60.7 0.0 1.3e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KIK46954.1 - 3.1e-08 33.3 0.0 5.3e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Blt1 PF12754.7 KIK46954.1 - 9.5e-05 22.7 1.7 9.5e-05 22.7 1.7 2.1 1 1 1 2 2 2 1 Blt1 N-terminal domain Rad60-SLD_2 PF13881.6 KIK46954.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF1967 PF09269.11 KIK46954.1 - 0.1 12.5 0.2 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Ndufs5 PF10200.9 KIK46955.1 - 3e-05 24.2 0.6 3.9e-05 23.8 0.6 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.10 KIK46955.1 - 0.0012 18.9 1.6 0.0017 18.4 1.6 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Defensin_5 PF18251.1 KIK46955.1 - 0.036 14.1 0.4 0.075 13.1 0.4 1.6 1 0 0 1 1 1 0 Fungal defensin Copsin PADR1 PF08063.12 KIK46955.1 - 0.048 13.5 3.0 5.8 6.8 0.0 2.7 2 1 1 3 3 3 0 PADR1 (NUC008) domain Pet191_N PF10203.9 KIK46955.1 - 0.07 13.4 0.8 0.11 12.8 0.8 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 KIK46955.1 - 0.23 11.7 6.0 3 8.1 0.4 2.2 1 1 1 2 2 2 0 CHCH domain DUF3128 PF11326.8 KIK46955.1 - 0.43 11.0 5.0 1.5 9.2 4.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) COX6B PF02297.17 KIK46955.1 - 2.4 8.4 6.5 4.5 7.6 0.3 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DUF4659 PF15558.6 KIK46956.1 - 0.0054 15.7 1.7 0.0061 15.5 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4659) UQ_con PF00179.26 KIK46957.1 - 2.8e-48 163.1 0.0 3.1e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KIK46957.1 - 0.0012 19.2 0.0 0.0014 18.9 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KIK46957.1 - 0.0028 17.3 0.0 0.0033 17.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KIK46957.1 - 0.015 15.1 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain Zn_clus PF00172.18 KIK46959.1 - 3.5 7.8 14.2 1.1 9.5 2.9 2.7 2 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2203 PF09969.9 KIK46959.1 - 8.5 7.1 10.8 16 6.2 5.7 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) SRP-alpha_N PF04086.13 KIK46959.1 - 9.1 6.1 16.7 12 5.7 16.7 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Nup96 PF12110.8 KIK46960.1 - 3.4e-90 302.1 0.0 5.2e-90 301.5 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 FAM60A PF15396.6 KIK46960.1 - 0.021 14.8 2.5 0.038 14.0 2.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A SDA1 PF05285.12 KIK46960.1 - 1.3 8.3 8.4 2.2 7.6 8.4 1.4 1 0 0 1 1 1 0 SDA1 PIG-L PF02585.17 KIK46961.1 - 8.1e-17 62.1 0.0 1.2e-16 61.5 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF429 PF04250.13 KIK46962.1 - 0.064 13.0 0.0 0.069 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF429) WD40 PF00400.32 KIK46963.1 - 5.7e-29 99.8 9.6 1.8e-07 31.7 0.1 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK46963.1 - 7.6e-11 42.2 1.1 0.019 15.2 0.0 4.3 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK46963.1 - 0.0025 17.2 0.1 0.058 12.7 0.0 2.5 3 0 0 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 KIK46963.1 - 0.0063 15.5 0.2 1.7 7.5 0.0 2.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK46963.1 - 0.011 14.4 2.8 0.16 10.6 0.1 2.7 2 1 0 3 3 3 0 Nucleoporin Nup120/160 WW PF00397.26 KIK46964.1 - 0.0076 16.3 0.1 0.0076 16.3 0.1 1.9 2 0 0 2 2 2 1 WW domain DUF1770 PF08589.10 KIK46965.1 - 0.0003 21.7 0.6 0.00075 20.4 0.0 2.0 2 1 1 3 3 3 1 Fungal protein of unknown function (DUF1770) DUF3455 PF11937.8 KIK46966.1 - 2.1e-25 90.0 0.1 3.1e-25 89.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Peptidase_C14 PF00656.22 KIK46968.1 - 0.098 12.6 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Caspase domain Peptidase_C14 PF00656.22 KIK46970.1 - 1.1e-17 64.9 0.0 1.2e-17 64.8 0.0 1.0 1 0 0 1 1 1 1 Caspase domain DUF4894 PF16235.5 KIK46970.1 - 0.035 14.5 0.0 0.041 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4894) Peptidase_C14 PF00656.22 KIK46973.1 - 4.1e-28 99.0 0.0 6.5e-28 98.3 0.0 1.3 1 1 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KIK46973.1 - 0.038 14.0 1.1 0.78 9.7 0.5 2.8 2 1 0 2 2 2 0 Raptor N-terminal CASPase like domain NmrA PF05368.13 KIK46974.1 - 1.2e-43 149.3 0.0 1.5e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK46974.1 - 3.6e-18 66.1 0.0 4.7e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIK46974.1 - 0.00014 21.0 0.0 0.00027 20.1 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KIK46974.1 - 0.00036 20.1 0.0 0.00055 19.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KIK46974.1 - 0.14 11.6 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Peptidase_C14 PF00656.22 KIK46975.1 - 1.6e-24 87.3 0.1 2.1e-24 86.8 0.1 1.2 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 KIK46975.1 - 0.016 14.8 0.7 2.3 7.7 0.1 2.4 1 1 1 2 2 2 0 Peptidase C13 family LRR_6 PF13516.6 KIK46976.1 - 0.00011 21.9 3.1 0.016 15.2 0.1 4.1 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.7 KIK46976.1 - 0.31 11.5 1.3 8.2 7.0 0.0 3.4 1 1 4 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KIK46976.1 - 0.47 11.2 1.8 26 5.9 0.1 3.6 4 0 0 4 4 4 0 Leucine Rich Repeat DBR1 PF05011.13 KIK46977.1 - 6.8e-40 136.7 0.0 1.2e-39 135.9 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KIK46977.1 - 2.8e-09 37.8 0.5 3.9e-09 37.3 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIK46977.1 - 0.024 14.8 0.0 0.053 13.7 0.0 1.6 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain LPD22 PF18834.1 KIK46977.1 - 0.084 13.1 0.7 13 6.1 0.0 2.5 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 WW PF00397.26 KIK46978.1 - 0.017 15.2 0.9 0.042 13.9 0.0 2.1 2 0 0 2 2 2 0 WW domain YtpI PF14007.6 KIK46978.1 - 0.44 10.7 2.3 24 5.2 0.4 2.8 3 0 0 3 3 3 0 YtpI-like protein LRR_6 PF13516.6 KIK46979.1 - 3e-07 29.9 12.1 9.8e-05 22.1 0.2 5.0 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.7 KIK46979.1 - 8.2e-06 26.1 6.6 0.067 13.6 0.0 4.9 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) NmrA PF05368.13 KIK46980.1 - 6.7e-41 140.4 0.0 8.1e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK46980.1 - 3.3e-19 69.5 0.0 4.1e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIK46980.1 - 2e-05 23.7 0.0 7.1e-05 21.9 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KIK46980.1 - 0.00016 21.2 0.0 0.00039 20.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KIK46980.1 - 0.074 12.5 0.3 0.13 11.7 0.1 1.5 2 0 0 2 2 2 0 short chain dehydrogenase DapB_N PF01113.20 KIK46980.1 - 0.2 11.8 0.0 0.65 10.1 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus TFIIE_alpha PF02002.17 KIK46983.1 - 1.3e-08 34.6 0.3 2.9e-08 33.5 0.3 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 KIK46983.1 - 7.6e-06 25.3 1.4 1.7e-05 24.2 1.4 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding TFIIE-A_C PF11521.8 KIK46983.1 - 4.6e-05 23.6 0.4 4.6e-05 23.6 0.4 2.3 1 1 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha zf_UBZ PF18439.1 KIK46983.1 - 0.022 14.4 1.7 1.8 8.2 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger HNH PF01844.23 KIK46983.1 - 0.064 13.4 0.4 3 8.1 0.1 2.3 2 0 0 2 2 2 0 HNH endonuclease zf-C4_ClpX PF06689.13 KIK46983.1 - 0.11 12.4 0.8 5.1 7.1 0.1 2.4 2 0 0 2 2 2 0 ClpX C4-type zinc finger PhnA_Zn_Ribbon PF08274.12 KIK46983.1 - 0.48 10.4 4.8 15 5.6 5.2 2.3 1 1 1 2 2 2 0 PhnA Zinc-Ribbon Oxidored_FMN PF00724.20 KIK46984.1 - 8e-35 120.7 0.0 4.9e-34 118.1 0.0 1.9 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Aldo_ket_red PF00248.21 KIK46985.1 - 4.2e-40 137.8 0.0 1.8e-38 132.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family PX PF00787.24 KIK46987.1 - 8.5e-20 70.8 0.0 1.7e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.9 KIK46987.1 - 1.1e-15 57.7 2.7 6.2e-15 55.3 3.4 1.7 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein SH3_1 PF00018.28 KIK46987.1 - 2.3e-07 30.3 0.0 4.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK46987.1 - 6e-05 22.8 0.1 0.00011 22.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain CUE PF02845.16 KIK46990.1 - 0.014 15.1 0.2 0.071 12.8 0.2 2.2 1 1 0 1 1 1 0 CUE domain Rep_fac-A_3 PF08661.11 KIK46991.1 - 2.8e-14 53.4 0.2 3e-14 53.2 0.2 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 WW PF00397.26 KIK46992.1 - 0.0097 16.0 1.2 0.017 15.2 0.0 2.0 2 0 0 2 2 2 1 WW domain WW PF00397.26 KIK46993.1 - 0.19 11.8 3.0 1.9 8.6 0.0 3.0 2 0 0 2 2 2 0 WW domain MMR_HSR1 PF01926.23 KIK46994.1 - 1e-06 28.8 2.0 1.2e-06 28.5 0.0 2.1 2 2 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK46994.1 - 0.00093 18.6 0.1 0.00093 18.6 0.1 1.8 2 1 1 3 3 3 1 AIG1 family Dynamin_N PF00350.23 KIK46994.1 - 0.0014 18.7 12.8 0.025 14.6 0.0 3.5 2 2 1 3 3 3 2 Dynamin family Septin PF00735.18 KIK46994.1 - 0.0039 16.5 0.0 0.012 14.9 0.0 1.9 1 1 0 1 1 1 1 Septin AAA_18 PF13238.6 KIK46994.1 - 0.014 15.9 1.6 0.4 11.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KIK46994.1 - 0.026 14.4 0.2 0.026 14.4 0.2 2.4 2 1 1 3 3 3 0 RsgA GTPase FeoB_N PF02421.18 KIK46994.1 - 0.088 12.3 0.0 0.26 10.8 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B Macoilin PF09726.9 KIK46994.1 - 0.28 9.7 10.0 0.3 9.6 10.0 1.1 1 0 0 1 1 1 0 Macoilin family AAA_22 PF13401.6 KIK46994.1 - 0.4 10.9 2.8 4.1 7.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain OmpH PF03938.14 KIK46994.1 - 0.56 10.5 20.0 2.1 8.7 19.8 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) CorA PF01544.18 KIK46994.1 - 0.66 9.2 6.6 0.95 8.7 6.6 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4407 PF14362.6 KIK46994.1 - 1.1 8.6 15.8 1.6 8.0 15.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 KIK46994.1 - 1.1 9.3 13.5 1.6 8.8 13.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3584 PF12128.8 KIK46994.1 - 1.2 6.6 19.9 1.4 6.3 19.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF724 PF05266.14 KIK46994.1 - 2.2 8.1 12.7 2.4 8.0 11.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) PRKG1_interact PF15898.5 KIK46994.1 - 6.3 7.8 17.4 5.7 7.9 15.3 1.9 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain IIGP PF05049.13 KIK46995.1 - 6.3e-26 91.3 0.0 1.1e-25 90.5 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KIK46995.1 - 2.1e-06 27.8 0.1 6.1e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KIK46995.1 - 0.0038 17.7 1.4 0.012 16.2 0.0 2.1 2 1 0 2 2 2 1 ABC transporter Dynamin_N PF00350.23 KIK46995.1 - 0.0039 17.3 0.5 0.0039 17.3 0.5 2.4 2 1 1 3 3 3 1 Dynamin family ATP_bind_1 PF03029.17 KIK46995.1 - 0.0082 15.9 0.9 1.9 8.2 0.0 2.8 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KIK46995.1 - 0.016 15.5 2.2 0.59 10.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain FeoB_N PF02421.18 KIK46995.1 - 0.023 14.2 0.0 0.059 12.9 0.0 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B Roc PF08477.13 KIK46995.1 - 0.025 14.8 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KIK46995.1 - 0.026 14.4 0.0 0.073 13.0 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KIK46995.1 - 0.047 14.1 3.8 0.71 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain MCM PF00493.23 KIK46995.1 - 0.063 12.4 0.1 4.1 6.4 0.0 2.6 3 0 0 3 3 3 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 KIK46995.1 - 0.18 11.2 0.0 0.18 11.2 0.0 2.1 2 1 0 3 3 3 0 FtsK/SpoIIIE family AAA_29 PF13555.6 KIK46995.1 - 0.18 11.6 0.2 0.59 9.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KIK46995.1 - 0.29 10.4 7.1 2.4 7.4 0.0 3.3 3 1 0 3 3 3 0 Zeta toxin SMC_N PF02463.19 KIK46995.1 - 0.3 10.5 0.7 0.64 9.4 0.1 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 KIK46995.1 - 0.79 9.8 5.8 0.51 10.4 0.3 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain ARGLU PF15346.6 KIK46995.1 - 2.3 8.1 21.4 0.33 10.8 17.2 1.7 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 IIGP PF05049.13 KIK46997.1 - 0.00051 19.2 0.9 0.0016 17.5 0.0 2.0 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Apt1 PF10351.9 KIK46997.1 - 0.0076 15.2 1.7 0.012 14.5 1.7 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain ERM PF00769.19 KIK46997.1 - 0.027 14.3 23.1 0.051 13.4 23.1 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.12 KIK46997.1 - 0.027 14.5 21.6 0.046 13.8 21.6 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 KIK46997.1 - 0.075 12.4 13.7 0.12 11.7 13.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KIK46997.1 - 0.078 11.9 9.4 0.12 11.3 9.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FapA PF03961.13 KIK46997.1 - 0.087 11.4 2.4 0.12 11.0 2.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A OEP PF02321.18 KIK46997.1 - 0.088 12.6 15.2 0.17 11.7 15.2 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein Alanine_zipper PF11839.8 KIK46997.1 - 0.089 13.2 27.6 0.64 10.4 9.1 2.3 1 1 1 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Zwint PF15556.6 KIK46997.1 - 0.69 9.4 13.3 0.82 9.1 12.5 1.4 1 1 0 1 1 1 0 ZW10 interactor ApoLp-III PF07464.11 KIK46997.1 - 1.6 8.8 7.0 5 7.2 7.0 1.6 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) V_ATPase_I PF01496.19 KIK46997.1 - 1.9 6.3 6.1 2.5 5.9 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FTCD_C PF04961.12 KIK46997.1 - 2.2 8.0 8.1 3.4 7.4 8.1 1.2 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase HSP70 PF00012.20 KIK46997.1 - 2.6 6.1 10.2 3.7 5.6 10.2 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF948 PF06103.11 KIK46997.1 - 4.4 7.6 4.6 10 6.5 1.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Rotamase_3 PF13616.6 KIK46998.1 - 8.3e-19 68.3 0.1 1.5e-18 67.4 0.1 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KIK46998.1 - 3.5e-16 59.9 0.3 7e-16 59.0 0.0 1.6 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KIK46998.1 - 3e-05 24.8 1.1 0.00011 23.0 0.0 1.9 1 1 1 2 2 2 1 PPIC-type PPIASE domain Myb_DNA-binding PF00249.31 KIK46999.1 - 7.2e-13 48.5 0.0 1.5e-06 28.3 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK46999.1 - 2.9e-05 24.2 0.2 0.028 14.6 0.0 2.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KIK46999.1 - 0.00031 20.6 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 2 Myb DNA-binding like DUF2664 PF10867.8 KIK46999.1 - 0.059 13.8 0.5 0.13 12.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2664) PIG-S PF10510.9 KIK47000.1 - 3.6e-117 392.3 9.3 6.3e-117 391.5 9.3 1.4 1 1 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DUF5422 PF17459.2 KIK47000.1 - 0.14 12.3 0.3 4.3 7.5 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5422) CLTH PF10607.9 KIK47001.1 - 5.4e-32 110.7 1.0 9.2e-32 110.0 1.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain ADP_ribosyl_GH PF03747.14 KIK47001.1 - 0.053 13.3 0.7 1.3 8.7 0.1 2.1 2 0 0 2 2 2 0 ADP-ribosylglycohydrolase NADH-G_4Fe-4S_3 PF10588.9 KIK47001.1 - 0.082 12.5 0.8 0.45 10.1 0.8 2.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region HlyIII PF03006.20 KIK47002.1 - 1.1e-55 188.8 18.1 1.3e-55 188.5 18.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related p450 PF00067.22 KIK47003.1 - 2.4e-32 112.3 0.0 4e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Neugrin PF06413.11 KIK47004.1 - 1.4e-11 44.9 1.2 2.7e-11 43.9 1.2 1.5 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 KIK47004.1 - 0.029 14.5 8.6 0.091 12.9 8.6 1.7 1 1 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 Sof1 PF04158.14 KIK47004.1 - 0.06 13.6 6.0 0.12 12.7 6.0 1.5 1 0 0 1 1 1 0 Sof1-like domain Cofilin_ADF PF00241.20 KIK47005.1 - 7.9e-27 93.5 0.1 8.9e-27 93.3 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Acetyltransf_1 PF00583.25 KIK47006.1 - 1.4e-14 54.4 0.0 1.8e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK47006.1 - 4.1e-07 30.3 0.0 8e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIK47006.1 - 7.9e-06 25.8 0.0 1.4e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIK47006.1 - 0.00032 21.4 0.0 0.00048 20.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK47006.1 - 0.0015 18.5 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein NAC PF01849.18 KIK47007.1 - 7.8e-24 83.4 0.1 1.3e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 NAC domain MR_MLE_C PF13378.6 KIK47008.1 - 7.5e-48 163.0 0.2 8.3e-47 159.6 0.2 2.1 1 1 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KIK47008.1 - 1.2e-10 41.6 0.0 3e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Peptidase_C25_C PF03785.14 KIK47008.1 - 0.041 13.7 0.1 0.081 12.8 0.1 1.4 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain Pol_alpha_B_N PF08418.10 KIK47009.1 - 0.36 10.8 3.3 0.58 10.1 3.3 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal LIM PF00412.22 KIK47010.1 - 1.6e-32 111.5 24.4 6.9e-16 58.2 2.5 4.3 4 0 0 4 4 4 3 LIM domain Mut7-C PF01927.16 KIK47010.1 - 2.5 8.2 11.1 0.12 12.5 0.8 2.4 2 0 0 2 2 2 0 Mut7-C RNAse domain DUF2321 PF10083.9 KIK47010.1 - 8 6.1 13.9 6.7 6.3 3.4 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Suf PF05843.14 KIK47012.1 - 0.21 11.6 2.0 0.24 11.4 2.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Roughex PF06020.11 KIK47012.1 - 4.3 6.4 7.2 5.9 5.9 7.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein XPG_I PF00867.18 KIK47013.1 - 1e-12 48.2 0.0 2.5e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KIK47013.1 - 6e-06 26.7 0.0 1.2e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc_N PF02739.16 KIK47013.1 - 0.0025 17.7 0.0 0.67 9.8 0.0 2.4 2 0 0 2 2 2 2 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 KIK47013.1 - 0.006 17.2 0.0 0.015 15.9 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Coatomer_WDAD PF04053.14 KIK47014.1 - 1e-138 463.1 0.0 4.5e-138 461.0 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 KIK47014.1 - 2.3e-112 375.7 0.0 3.5e-112 375.1 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KIK47014.1 - 5.3e-45 150.5 12.6 6.2e-08 33.2 0.2 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK47014.1 - 1.7e-12 47.5 1.0 0.00066 19.9 0.0 5.7 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_14 PF13428.6 KIK47014.1 - 0.041 14.7 9.8 0.82 10.7 0.5 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Clathrin PF00637.20 KIK47014.1 - 0.047 13.6 0.2 0.52 10.2 0.1 2.5 3 0 0 3 3 3 0 Region in Clathrin and VPS TPR_2 PF07719.17 KIK47014.1 - 0.058 13.5 0.7 24 5.4 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Nup160 PF11715.8 KIK47014.1 - 0.17 10.5 5.3 14 4.1 0.1 3.7 3 1 1 4 4 4 0 Nucleoporin Nup120/160 TPR_16 PF13432.6 KIK47014.1 - 0.36 11.5 1.7 5.9 7.6 0.5 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DNA_pol_phi PF04931.13 KIK47014.1 - 6.1 4.8 7.1 11 4.0 7.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi Trp_halogenase PF04820.14 KIK47015.1 - 7.6e-27 94.3 0.1 5e-14 52.0 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KIK47015.1 - 1.9e-12 47.1 0.0 4.4e-12 45.9 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KIK47015.1 - 2.6e-07 30.7 0.1 7.5e-07 29.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIK47015.1 - 1.4e-06 27.6 0.0 0.00043 19.5 0.0 2.6 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 KIK47015.1 - 1.7e-06 27.6 0.0 4.7e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK47015.1 - 1.5e-05 24.4 0.0 2.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK47015.1 - 1.5e-05 24.7 0.1 0.00034 20.3 0.1 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIK47015.1 - 3.6e-05 22.6 0.0 5.6e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KIK47015.1 - 4.2e-05 22.8 0.0 6.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KIK47015.1 - 0.0018 18.8 0.0 0.018 15.6 0.0 2.5 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK47015.1 - 0.046 12.9 0.0 0.088 12.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KIK47015.1 - 0.05 12.6 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KIK47015.1 - 0.062 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KIK47015.1 - 0.064 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 KIK47015.1 - 0.089 12.1 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Yuri_gagarin PF15934.5 KIK47016.1 - 0.05 13.4 0.1 0.066 13.1 0.1 1.2 1 0 0 1 1 1 0 Yuri gagarin SPA PF08616.10 KIK47017.1 - 5e-29 100.6 0.0 9.1e-29 99.7 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 KIK47017.1 - 1.5e-21 77.2 0.2 3.7e-16 59.8 0.1 2.5 2 0 0 2 2 2 2 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 KIK47017.1 - 1.5e-05 23.9 0.0 0.0029 16.4 0.0 3.1 3 0 0 3 3 3 2 Transport protein Avl9 DUF2347 PF09804.9 KIK47017.1 - 0.15 11.6 0.0 20 4.6 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) EcsB PF05975.12 KIK47018.1 - 0.021 13.7 2.0 0.031 13.1 2.0 1.2 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB NDUFA12 PF05071.16 KIK47022.1 - 1.9e-07 31.8 2.3 3.3e-07 31.1 2.3 1.5 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 UPF0449 PF15136.6 KIK47022.1 - 0.0055 17.2 0.5 0.0095 16.4 0.2 1.5 2 0 0 2 2 2 1 Uncharacterised protein family UPF0449 PCI PF01399.27 KIK47023.1 - 3.2e-23 82.2 0.1 1.3e-22 80.3 0.0 2.0 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.11 KIK47023.1 - 1.5e-20 73.4 0.1 1.5e-20 73.4 0.1 2.8 3 0 0 3 3 3 1 Proteasome regulatory subunit C-terminal Sigma70_r1_2 PF00140.20 KIK47023.1 - 0.32 11.0 2.7 0.88 9.6 2.7 1.8 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 TPR_16 PF13432.6 KIK47023.1 - 1 10.1 8.5 1.9 9.2 0.7 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK47023.1 - 7.4 6.9 6.7 0.63 10.3 0.6 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribophorin_II PF05817.14 KIK47024.1 - 2.6e-33 115.5 0.0 3.3e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Ycf9 PF01737.17 KIK47025.1 - 0.14 12.1 0.2 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 YCF9 CCDC73 PF15818.5 KIK47026.1 - 0.087 10.7 2.6 0.1 10.5 2.6 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 73 family Glucan_synthase PF02364.15 KIK47028.1 - 0 1326.3 0.0 0 1325.9 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KIK47028.1 - 2.1e-42 144.5 0.1 6.4e-42 142.9 0.1 1.9 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 SpoIIE PF07228.12 KIK47030.1 - 2e-09 37.6 0.0 3.3e-09 36.9 0.0 1.3 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KIK47030.1 - 0.00055 19.6 0.0 0.001 18.7 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C DUF202 PF02656.15 KIK47030.1 - 0.051 14.0 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF202) PP2C PF00481.21 KIK47030.1 - 0.085 12.5 0.0 1 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein phosphatase 2C DNA_pol3_gamma3 PF12169.8 KIK47030.1 - 0.22 11.4 0.0 0.38 10.7 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III Peptidase_M49 PF03571.15 KIK47031.1 - 2.6e-226 752.3 0.0 3.2e-226 752.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 4HB PF17947.1 KIK47031.1 - 0.18 11.9 0.4 5.6 7.1 0.1 2.6 2 0 0 2 2 2 0 Four helical bundle domain FAD_binding_3 PF01494.19 KIK47032.1 - 2.7e-50 171.6 0.3 9e-34 117.2 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 KIK47032.1 - 5.4e-07 29.3 0.0 6.4e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK47032.1 - 9.1e-07 28.4 0.6 2.7e-06 26.8 0.6 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK47032.1 - 3.5e-06 26.5 0.1 0.00029 20.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK47032.1 - 1.6e-05 24.7 0.5 0.0064 16.1 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK47032.1 - 3e-05 23.3 0.4 0.0007 18.8 0.2 2.2 1 1 1 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KIK47032.1 - 0.00012 21.0 0.3 0.066 11.9 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.12 KIK47032.1 - 0.0012 18.0 0.6 0.0048 16.0 0.6 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KIK47032.1 - 0.0015 18.6 0.2 0.078 13.0 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KIK47032.1 - 0.0053 17.0 0.1 0.015 15.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIK47032.1 - 0.0065 15.7 0.4 0.014 14.7 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 KIK47032.1 - 0.0066 15.4 0.3 1.1 8.0 0.0 2.1 1 1 0 2 2 2 2 Tryptophan halogenase Amino_oxidase PF01593.24 KIK47032.1 - 0.0078 15.5 0.2 3.1 7.0 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SE PF08491.10 KIK47032.1 - 0.0084 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Shikimate_DH PF01488.20 KIK47032.1 - 0.031 14.3 0.1 0.08 13.0 0.1 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KIK47032.1 - 0.045 14.3 0.1 7.7 7.2 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIK47032.1 - 0.06 12.4 0.7 0.7 8.9 0.4 2.3 2 1 1 3 3 3 0 Glucose inhibited division protein A Complex1_LYR PF05347.15 KIK47033.1 - 3.2e-10 39.9 0.0 4e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) HIG_1_N PF04588.13 KIK47034.1 - 3.4e-19 68.8 1.0 5.3e-19 68.2 1.0 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region FAD_binding_3 PF01494.19 KIK47035.1 - 3e-11 43.1 0.0 1.7e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain TPR_2 PF07719.17 KIK47036.1 - 3.8e-05 23.5 1.8 0.1 12.8 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIK47036.1 - 5.4e-05 23.4 9.3 0.23 11.8 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KIK47036.1 - 0.00028 20.6 0.6 4.6 7.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK47036.1 - 0.042 13.7 0.3 5.2 7.1 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK47036.1 - 0.071 12.8 0.1 3.4 7.4 0.0 2.6 2 0 0 2 2 2 0 TPR repeat TPR_8 PF13181.6 KIK47036.1 - 0.19 12.0 0.8 16 6.0 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 KIK47036.1 - 0.31 11.8 2.0 18 6.2 0.0 3.1 3 0 0 3 3 3 0 Sel1 repeat Cellulase PF00150.18 KIK47038.1 - 1.8e-17 63.7 0.3 1.5e-16 60.7 0.3 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 KIK47038.1 - 0.0005 19.5 1.1 0.25 10.7 0.2 2.9 2 1 0 2 2 2 2 Beta-galactosidase Glyco_hydro_2_C PF02836.17 KIK47038.1 - 0.016 14.3 0.3 0.035 13.2 0.3 1.6 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DEAD_2 PF06733.15 KIK47039.1 - 4.5e-52 176.2 0.0 8.6e-52 175.3 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 KIK47039.1 - 1.9e-45 154.9 3.6 1.7e-40 138.7 0.5 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KIK47039.1 - 1.1e-43 149.4 0.0 2.3e-43 148.3 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 KIK47039.1 - 0.00091 19.3 1.4 0.032 14.2 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIK47039.1 - 0.0047 16.7 0.1 1.1 9.0 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase SNF2_N PF00176.23 KIK47039.1 - 0.072 11.8 0.1 2.7 6.6 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain DUF2058 PF09831.9 KIK47039.1 - 0.1 12.8 4.2 0.077 13.1 0.5 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Exog_C PF18026.1 KIK47039.1 - 0.11 12.6 0.7 1.5 8.9 0.1 2.7 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain Peptidase_M41 PF01434.18 KIK47041.1 - 2.1e-60 203.8 0.5 3.4e-60 203.2 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KIK47041.1 - 8.5e-41 139.5 0.0 1.6e-40 138.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIK47041.1 - 5.6e-11 42.1 0.0 1.4e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KIK47041.1 - 3.2e-05 24.4 1.0 0.003 18.0 0.1 3.0 1 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 KIK47041.1 - 4.6e-05 22.8 0.1 0.00023 20.5 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 KIK47041.1 - 6.3e-05 22.8 0.0 0.00017 21.4 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KIK47041.1 - 0.00018 21.5 0.0 0.00052 20.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIK47041.1 - 0.00085 19.6 0.3 0.013 15.7 0.3 2.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIK47041.1 - 0.0036 17.8 0.0 0.01 16.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 KIK47041.1 - 0.004 16.9 0.0 0.0088 15.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 KIK47041.1 - 0.0041 16.7 0.5 0.33 10.5 0.3 2.8 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KIK47041.1 - 0.0048 16.3 0.5 0.011 15.2 0.5 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KIK47041.1 - 0.0053 17.0 0.1 0.022 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIK47041.1 - 0.016 15.4 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KIK47041.1 - 0.017 15.1 0.1 0.076 12.9 0.1 2.1 2 0 0 2 2 2 0 NACHT domain AAA_2 PF07724.14 KIK47041.1 - 0.022 14.9 0.0 0.063 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 KIK47041.1 - 0.045 13.8 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KIK47041.1 - 0.066 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 KIK47041.1 - 0.066 13.6 0.0 0.19 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATP-cone PF03477.16 KIK47041.1 - 0.098 13.2 0.5 2.2 8.9 0.0 2.6 2 1 0 2 2 2 0 ATP cone domain Sigma54_activat PF00158.26 KIK47041.1 - 0.12 12.1 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 KIK47041.1 - 0.12 11.9 0.1 0.43 10.1 0.1 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KIK47041.1 - 0.13 11.3 0.0 0.27 10.3 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 GCIP PF13324.6 KIK47042.1 - 1.1e-44 153.1 0.1 2.3e-44 152.0 0.0 1.5 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting tRNA-synt_2d PF01409.20 KIK47044.1 - 2.9e-45 154.7 0.0 2.9e-24 85.9 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KIK47044.1 - 1.2e-23 83.3 0.0 2.3e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain GrpE PF01025.19 KIK47045.1 - 2.8e-43 147.5 0.1 5.6e-43 146.5 0.1 1.4 1 1 0 1 1 1 1 GrpE FTHFS PF01268.19 KIK47046.1 - 1.5e-255 848.7 0.0 2e-255 848.3 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KIK47046.1 - 1.2e-62 210.0 0.8 1.2e-62 210.0 0.8 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KIK47046.1 - 2.3e-37 127.8 0.4 5.6e-37 126.6 0.4 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 KIK47046.1 - 0.018 14.0 0.2 0.036 13.0 0.2 1.4 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family PNGaseA PF12222.8 KIK47047.1 - 1.3e-134 449.3 3.9 1.8e-134 448.9 3.9 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A BACON PF13004.7 KIK47047.1 - 0.25 11.4 4.3 0.19 11.7 0.2 2.8 2 0 0 2 2 2 0 Putative binding domain, N-terminal CTP_transf_like PF01467.26 KIK47049.1 - 1.6e-21 77.0 0.0 2.1e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like UbiA PF01040.18 KIK47050.1 - 2.4e-06 27.0 2.2 2.4e-06 27.0 2.2 2.3 2 0 0 2 2 2 1 UbiA prenyltransferase family DUF5575 PF17738.1 KIK47050.1 - 2e-05 23.8 0.1 3.2e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5575) DUF2752 PF10825.8 KIK47050.1 - 0.026 14.6 1.7 5.9 7.0 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) Pmp3 PF01679.17 KIK47051.1 - 2.7e-17 62.7 3.7 3.7e-17 62.2 3.7 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator FAM104 PF15434.6 KIK47051.1 - 0.044 14.4 0.6 0.044 14.4 0.6 1.9 2 0 0 2 2 2 0 Family 104 zf-C2H2 PF00096.26 KIK47052.1 - 3.2e-20 71.4 30.6 2.2e-05 24.6 1.6 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK47052.1 - 3.8e-19 68.2 31.1 6.6e-07 29.5 2.0 5.9 6 0 0 6 6 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK47052.1 - 1.7e-11 43.9 24.1 0.013 16.2 0.6 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK47052.1 - 1.1e-05 25.6 3.6 1.5 9.2 0.0 5.1 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIK47052.1 - 9.9e-05 22.6 5.4 0.19 12.2 0.0 4.3 5 0 0 5 5 5 2 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KIK47052.1 - 0.00088 19.9 11.4 0.4 11.4 0.3 4.4 3 1 2 5 5 4 2 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 KIK47052.1 - 0.0047 16.6 14.5 0.13 12.1 0.3 4.2 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-CGNR PF11706.8 KIK47052.1 - 0.046 13.6 8.4 18 5.3 0.1 4.4 4 0 0 4 4 4 0 CGNR zinc finger zf-C2H2_8 PF15909.5 KIK47052.1 - 0.12 12.7 7.1 2.9 8.3 1.5 3.0 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-TRAF PF02176.18 KIK47052.1 - 0.4 11.4 12.6 0.34 11.6 2.5 3.2 1 1 2 3 3 3 0 TRAF-type zinc finger zf-C2H2_6 PF13912.6 KIK47052.1 - 0.49 10.5 7.7 1.1 9.4 0.1 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger Ogr_Delta PF04606.12 KIK47052.1 - 8 6.5 7.6 5.6 7.0 1.3 2.9 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger FBPase PF00316.20 KIK47053.1 - 3.5e-75 251.6 0.5 4.4e-75 251.3 0.5 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KIK47053.1 - 0.00024 20.7 0.0 0.00039 20.0 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family bZIP_2 PF07716.15 KIK47054.1 - 8.7e-10 38.5 15.6 1.4e-09 37.9 15.6 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KIK47054.1 - 2.9e-05 24.1 8.8 6.6e-05 22.9 8.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor Stathmin PF00836.19 KIK47054.1 - 0.0076 16.2 4.6 0.014 15.4 4.6 1.4 1 0 0 1 1 1 1 Stathmin family TSC22 PF01166.18 KIK47054.1 - 0.13 12.6 0.4 0.24 11.7 0.4 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Hamartin PF04388.12 KIK47054.1 - 1.6 7.3 4.7 1.9 7.1 4.7 1.1 1 0 0 1 1 1 0 Hamartin protein Ndc1_Nup PF09531.10 KIK47054.1 - 5.5 5.6 4.8 7.3 5.1 4.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4212 PF13937.6 KIK47055.1 - 0.00057 20.2 0.8 0.00078 19.8 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4212) PAP2 PF01569.21 KIK47056.1 - 1.8e-11 43.9 5.2 3.5e-11 43.0 5.0 1.7 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 KIK47056.1 - 0.0046 17.1 2.0 0.32 11.1 0.1 3.1 1 1 2 3 3 3 1 Divergent PAP2 family PaaX PF07848.12 KIK47057.1 - 0.039 14.2 0.0 0.052 13.8 0.0 1.2 1 0 0 1 1 1 0 PaaX-like protein MFS_1 PF07690.16 KIK47058.1 - 9.2e-29 100.5 38.5 1.2e-28 100.0 38.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK47058.1 - 0.00013 20.6 2.8 0.00013 20.6 2.8 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) UNC-93 PF05978.16 KIK47058.1 - 1.9 8.2 7.3 1.3 8.8 0.2 3.1 2 1 1 3 3 3 0 Ion channel regulatory protein UNC-93 DUF2418 PF10332.9 KIK47059.1 - 7.5e-28 96.9 0.1 1.9e-27 95.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) PGAP1 PF07819.13 KIK47060.1 - 1.3e-53 182.1 0.0 1.8e-53 181.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KIK47060.1 - 1.2e-08 35.9 0.8 4.2e-08 34.1 0.8 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK47060.1 - 1.6e-05 24.7 0.0 2.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK47060.1 - 0.003 16.9 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 KIK47060.1 - 0.0038 16.8 0.0 0.0085 15.7 0.0 1.5 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 KIK47060.1 - 0.075 12.9 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF3552 PF12072.8 KIK47061.1 - 0.00095 18.6 4.7 0.0029 17.0 2.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) Claudin_2 PF13903.6 KIK47061.1 - 0.083 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF3915 PF13054.6 KIK47061.1 - 0.1 12.6 0.5 0.1 12.6 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Ribosomal_S27e PF01667.17 KIK47061.1 - 0.13 12.0 0.6 11 5.8 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S27 DUF3450 PF11932.8 KIK47062.1 - 0.0022 17.4 4.5 0.0062 15.9 4.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) AIP3 PF03915.13 KIK47062.1 - 0.0098 15.0 6.3 0.023 13.8 6.3 1.6 1 0 0 1 1 1 1 Actin interacting protein 3 zf-CCCH_4 PF18044.1 KIK47062.1 - 0.022 14.6 2.7 0.04 13.7 2.7 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger TMPIT PF07851.13 KIK47062.1 - 0.024 13.9 6.0 0.04 13.2 6.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein zf-CCCH PF00642.24 KIK47062.1 - 0.024 14.6 4.5 0.082 12.8 4.5 1.8 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KIK47062.1 - 0.076 13.5 0.2 0.17 12.4 0.2 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger HutP PF09021.11 KIK47062.1 - 0.16 12.3 1.5 0.32 11.3 1.5 1.5 1 0 0 1 1 1 0 HutP LMBR1 PF04791.16 KIK47062.1 - 0.32 9.8 0.6 0.4 9.5 0.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein YabA PF06156.13 KIK47062.1 - 1.1 10.0 8.0 0.82 10.3 5.4 2.1 2 0 0 2 2 2 0 Initiation control protein YabA Fez1 PF06818.15 KIK47062.1 - 1.2 9.6 10.1 0.046 14.2 2.1 2.5 3 0 0 3 3 3 0 Fez1 Spc7 PF08317.11 KIK47062.1 - 2.8 6.7 12.3 5.7 5.7 12.3 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Rab5-bind PF09311.11 KIK47062.1 - 4.2 6.7 12.6 2.1 7.6 9.7 1.8 2 0 0 2 2 2 0 Rabaptin-like protein DUF1664 PF07889.12 KIK47062.1 - 4.6 7.3 7.1 32 4.6 4.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KIK47062.1 - 6 6.1 12.3 1.3 8.3 7.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 KIK47062.1 - 8.3 6.6 18.1 46 4.2 14.4 2.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Hemerythrin PF01814.23 KIK47063.1 - 0.0099 16.5 0.4 0.87 10.2 0.1 3.2 2 1 1 3 3 2 1 Hemerythrin HHE cation binding domain HMMR_C PF15908.5 KIK47063.1 - 0.019 15.3 2.3 0.019 15.3 2.3 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Shugoshin_N PF07558.11 KIK47063.1 - 0.097 12.5 2.6 0.23 11.4 0.4 2.6 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region FUSC PF04632.12 KIK47063.1 - 0.1 11.1 0.7 0.16 10.5 0.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family PikAIV_N PF18605.1 KIK47063.1 - 0.13 11.9 0.9 0.33 10.6 0.9 1.8 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Laminin_II PF06009.12 KIK47063.1 - 0.15 12.0 8.3 0.77 9.8 6.1 2.8 3 0 0 3 3 3 0 Laminin Domain II EDR1 PF14381.6 KIK47063.1 - 0.2 11.3 0.6 1.2 8.8 0.5 2.1 1 1 1 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 YabA PF06156.13 KIK47063.1 - 0.22 12.2 11.9 0.13 12.9 4.4 3.5 4 0 0 4 4 3 0 Initiation control protein YabA CENP-H PF05837.12 KIK47063.1 - 3 8.3 13.5 0.26 11.7 6.1 2.8 3 0 0 3 3 3 0 Centromere protein H (CENP-H) FlaC_arch PF05377.11 KIK47063.1 - 4.5 7.8 13.3 6.6 7.2 0.0 5.0 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 KIK47063.1 - 6.6 7.4 6.7 85 3.9 1.3 4.1 2 1 1 3 3 3 0 SlyX TolA_bind_tri PF16331.5 KIK47063.1 - 7.9 6.6 11.0 0.18 11.9 1.3 3.3 4 0 0 4 4 4 0 TolA binding protein trimerisation DivIC PF04977.15 KIK47063.1 - 8.8 6.2 8.5 11 5.9 3.2 3.7 2 1 1 3 3 3 0 Septum formation initiator ZapB PF06005.12 KIK47063.1 - 9.6 6.7 13.3 2.9 8.4 6.2 3.6 4 1 0 4 4 4 0 Cell division protein ZapB Vps55 PF04133.14 KIK47064.1 - 9.3e-43 144.9 4.5 1e-42 144.8 4.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2933 PF11666.8 KIK47064.1 - 1.4 9.0 5.5 3 8.0 5.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) Kinesin PF00225.23 KIK47065.1 - 2.1e-109 365.5 0.1 2.8e-108 361.8 0.0 2.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KIK47065.1 - 5.7e-24 84.8 0.0 2e-23 83.0 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding Microtub_bind PF13931.6 KIK47065.1 - 0.004 17.5 1.5 0.004 17.5 1.5 4.2 3 1 0 4 4 4 1 Kinesin-associated microtubule-binding TetR_C_20 PF17925.1 KIK47065.1 - 0.016 15.5 1.3 8 6.8 0.0 3.8 3 1 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain UxaC PF02614.14 KIK47065.1 - 0.2 10.5 5.3 0.33 9.8 4.8 1.7 2 0 0 2 2 2 0 Glucuronate isomerase WXG100 PF06013.12 KIK47065.1 - 4.6 7.5 18.0 6.3 7.1 8.3 4.8 3 1 1 4 4 4 0 Proteins of 100 residues with WXG Elf1 PF05129.13 KIK47066.1 - 4.4e-28 97.2 0.7 5.4e-28 96.9 0.7 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-CHY PF05495.12 KIK47066.1 - 0.0093 16.4 0.6 0.014 15.9 0.6 1.3 1 0 0 1 1 1 1 CHY zinc finger Nup96 PF12110.8 KIK47066.1 - 0.022 13.9 0.0 0.026 13.7 0.0 1.1 1 0 0 1 1 1 0 Nuclear protein 96 Kinesin PF00225.23 KIK47067.1 - 4.8e-91 305.2 2.4 4.8e-91 305.2 2.4 3.0 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KIK47067.1 - 4.7e-11 42.8 0.0 2.7e-10 40.4 0.0 2.4 1 1 0 1 1 1 1 Microtubule binding PTR PF12789.7 KIK47067.1 - 0.17 12.0 0.9 0.65 10.1 0.1 2.5 3 0 0 3 3 3 0 Phage tail repeat like TFA2_Winged_2 PF18121.1 KIK47067.1 - 1.4 8.7 4.3 2.2 8.0 0.7 3.4 4 0 0 4 4 4 0 TFA2 Winged helix domain 2 DUF3584 PF12128.8 KIK47067.1 - 9.8 3.5 70.9 2.9 5.3 24.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) PUF PF00806.19 KIK47069.1 - 5.7e-68 221.0 5.0 1.5e-09 37.0 0.0 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 KIK47069.1 - 0.0021 17.9 0.2 0.71 9.7 0.0 3.8 3 1 0 4 4 4 1 Single Cache domain 2 Sec16_C PF12931.7 KIK47070.1 - 1.4e-104 350.0 0.0 1.8e-104 349.6 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KIK47070.1 - 1.8e-27 96.3 0.7 1.2e-26 93.7 0.0 2.8 3 0 0 3 3 3 1 Vesicle coat trafficking protein Sec16 mid-region EKLF_TAD1 PF16832.5 KIK47070.1 - 0.033 14.1 2.3 0.54 10.2 0.3 2.9 2 0 0 2 2 2 0 Erythroid krueppel-like transcription factor, transactivation 1 OST3_OST6 PF04756.13 KIK47071.1 - 4.7e-92 308.5 0.0 5.3e-92 308.3 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 KIK47071.1 - 0.0018 18.2 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin PI3_PI4_kinase PF00454.27 KIK47072.1 - 8e-36 124.1 0.0 7.7e-35 120.9 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PhdYeFM_antitox PF02604.19 KIK47072.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system Glyco_transf_15 PF01793.16 KIK47073.1 - 2.3e-130 434.6 7.4 3e-130 434.2 7.4 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.16 KIK47074.1 - 2.1e-113 378.9 7.0 2.6e-113 378.6 7.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Porin_3 PF01459.22 KIK47076.1 - 4.3e-88 295.3 3.3 5e-88 295.1 3.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin ABC_tran PF00005.27 KIK47077.1 - 1.3e-22 80.8 0.0 1.8e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIK47077.1 - 1.1e-06 28.7 0.2 0.044 13.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KIK47077.1 - 0.00011 22.5 0.1 0.00035 20.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 KIK47077.1 - 0.00012 21.6 0.0 0.0046 16.4 0.0 2.0 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIK47077.1 - 0.0013 19.3 0.0 0.0024 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KIK47077.1 - 0.0014 18.6 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KIK47077.1 - 0.0014 18.3 0.0 0.0036 17.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 KIK47077.1 - 0.0018 18.3 0.2 0.0043 17.0 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KIK47077.1 - 0.0024 18.3 0.0 0.0084 16.5 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain TsaE PF02367.17 KIK47077.1 - 0.0031 17.5 0.0 0.0069 16.4 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_13 PF13166.6 KIK47077.1 - 0.0037 16.0 0.0 0.18 10.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KIK47077.1 - 0.0062 16.7 0.1 0.041 14.1 0.1 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KIK47077.1 - 0.0094 15.7 0.0 0.035 13.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KIK47077.1 - 0.018 14.2 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.22 KIK47077.1 - 0.024 13.8 0.1 0.047 12.9 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.15 KIK47077.1 - 0.03 14.2 0.0 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA PF00004.29 KIK47077.1 - 0.037 14.5 0.3 0.45 10.9 0.3 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 KIK47077.1 - 0.046 13.8 0.2 0.43 10.6 0.1 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 KIK47077.1 - 0.052 13.7 0.1 0.13 12.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK47077.1 - 0.066 13.8 0.1 0.33 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KIK47077.1 - 0.069 13.1 0.1 1.3 9.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Phage_TAC_4 PF08748.11 KIK47077.1 - 0.086 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone cobW PF02492.19 KIK47077.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 KIK47077.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein CPT PF07931.12 KIK47077.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.6 KIK47077.1 - 0.18 12.1 0.0 1.2 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain CybS PF05328.12 KIK47078.1 - 2.1e-44 150.4 0.0 2.7e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit TRAPPC9-Trs120 PF08626.11 KIK47079.1 - 4.7e-211 703.3 0.0 7.6e-210 699.3 0.0 1.9 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DPM2 PF07297.12 KIK47080.1 - 1.1e-29 102.6 0.1 1.2e-29 102.4 0.1 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KIK47080.1 - 2.9e-05 24.0 0.2 3.3e-05 23.8 0.2 1.1 1 0 0 1 1 1 1 PIG-P HemY_N PF07219.13 KIK47080.1 - 0.42 10.8 2.7 0.73 10.1 0.1 2.1 1 1 1 2 2 2 0 HemY protein N-terminus UNC-79 PF14776.6 KIK47081.1 - 4.4e-05 22.5 0.0 9e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 C1_1 PF00130.22 KIK47081.1 - 0.11 12.4 26.1 0.014 15.3 7.9 3.3 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4211 PF13926.6 KIK47082.1 - 5.5e-35 120.5 0.0 1.4e-34 119.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) TFIID-18kDa PF02269.16 KIK47083.1 - 1.3e-19 70.0 0.1 1.7e-19 69.6 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit RRM_1 PF00076.22 KIK47084.1 - 4.4e-14 52.1 0.0 1.3e-13 50.5 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIK47084.1 - 3.4e-06 27.1 0.0 4.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KIK47084.1 - 0.00013 21.9 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 KIK47084.1 - 0.0019 18.2 0.0 0.0043 17.0 0.0 1.6 1 1 1 2 2 2 1 Nup53/35/40-type RNA recognition motif NACHT PF05729.12 KIK47085.1 - 0.025 14.5 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KIK47085.1 - 0.033 14.6 0.0 0.045 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain UvrD-helicase PF00580.21 KIK47085.1 - 0.047 13.2 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain IstB_IS21 PF01695.17 KIK47085.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 KIK47085.1 - 0.17 12.1 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK47085.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Pkinase PF00069.25 KIK47086.1 - 1.1e-09 38.1 0.0 2.6e-07 30.3 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK47086.1 - 0.00084 18.7 0.0 0.0015 17.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK47086.1 - 0.025 14.5 0.1 0.052 13.5 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KIK47086.1 - 0.17 11.2 0.6 0.4 10.0 0.6 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2040 PF09745.9 KIK47087.1 - 4.2e-38 130.1 24.9 4.2e-38 130.1 24.9 3.3 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) RNase_PH PF01138.21 KIK47088.1 - 8.3e-32 110.5 0.1 1.4e-31 109.7 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KIK47088.1 - 2e-05 24.5 0.0 3.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Oxidored_nitro PF00148.19 KIK47088.1 - 0.099 11.3 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase AA_permease_2 PF13520.6 KIK47089.1 - 9.2e-62 209.2 30.0 1.1e-61 208.9 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK47089.1 - 6.1e-27 94.3 26.4 7.8e-27 94.0 26.4 1.1 1 0 0 1 1 1 1 Amino acid permease SirB PF04247.12 KIK47089.1 - 0.029 14.5 0.8 0.029 14.5 0.8 2.9 3 1 0 3 3 3 0 Invasion gene expression up-regulator, SirB HMA PF00403.26 KIK47090.1 - 7.3e-12 45.6 0.2 1.1e-11 44.9 0.2 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain Ferric_reduct PF01794.19 KIK47091.1 - 9.1e-18 64.6 15.1 9.1e-18 64.6 15.1 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KIK47091.1 - 1.1e-16 61.3 0.0 2.5e-09 37.4 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KIK47091.1 - 1e-12 48.1 0.0 6e-12 45.6 0.0 2.3 2 0 0 2 2 2 1 FAD-binding domain Sen15 PF09631.10 KIK47092.1 - 6.5e-20 71.3 0.0 7.5e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein TRM PF02005.16 KIK47093.1 - 6.8e-116 387.5 0.0 1.1e-115 386.8 0.0 1.3 1 1 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Pkinase PF00069.25 KIK47094.1 - 2e-69 233.9 0.0 2.8e-69 233.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK47094.1 - 8.8e-47 159.6 0.0 1.3e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_1 PF00536.30 KIK47094.1 - 1.2e-13 51.2 0.0 3.3e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ras_bdg_2 PF14847.6 KIK47094.1 - 3.9e-13 49.6 0.0 7.2e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 KIK47094.1 - 6.4e-11 42.2 0.0 1.3e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 KIK47094.1 - 0.00047 19.6 0.0 0.0046 16.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KIK47094.1 - 0.002 17.0 1.3 0.0063 15.3 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase SAM_4 PF18017.1 KIK47094.1 - 0.0039 17.1 0.4 0.0083 16.1 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Alpha-amylase PF00128.24 KIK47095.1 - 7.4e-21 75.1 5.5 4.7e-18 65.9 5.5 3.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KIK47095.1 - 2.3e-16 60.3 0.1 4.1e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KIK47095.1 - 6.2e-08 32.4 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Histone PF00125.24 KIK47096.1 - 6.3e-22 78.3 2.4 8.4e-22 77.9 2.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KIK47096.1 - 2.9e-05 24.3 0.1 6.9e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KIK47096.1 - 0.00037 20.9 0.0 0.00065 20.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KIK47096.1 - 0.043 13.8 0.3 0.053 13.6 0.3 1.1 1 0 0 1 1 1 0 YscO-like protein DUF1018 PF06252.12 KIK47096.1 - 0.047 14.7 0.5 0.076 14.0 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) BTB PF00651.31 KIK47097.1 - 9.1e-07 29.1 0.0 2.6e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain RPN7 PF10602.9 KIK47097.1 - 0.064 13.0 0.0 5.6 6.6 0.0 2.3 2 0 0 2 2 2 0 26S proteasome subunit RPN7 DAGK_cat PF00781.24 KIK47098.1 - 3.6e-26 91.2 0.0 5.3e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF3328 PF11807.8 KIK47099.1 - 1.1e-45 156.1 0.1 1.4e-45 155.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) LAB_N PF07578.11 KIK47100.1 - 0.0017 18.4 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipid A Biosynthesis N-terminal domain DUF3328 PF11807.8 KIK47101.1 - 2.7e-56 190.8 0.3 3.4e-56 190.5 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Citrate_synt PF00285.21 KIK47101.1 - 0.08 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain Ependymin PF00811.18 KIK47101.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Ependymin zf-RVT PF13966.6 KIK47102.1 - 9e-06 26.3 0.9 1.8e-05 25.3 0.6 1.7 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.24 KIK47102.1 - 9.9e-06 25.8 0.1 2.8e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 RNase H UPF0515 PF15135.6 KIK47102.1 - 0.039 13.3 0.1 0.053 12.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 Rhabdo_M1 PF03342.13 KIK47103.1 - 0.00097 18.6 2.6 0.0012 18.2 2.3 1.2 1 1 0 1 1 1 1 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) dCache_2 PF08269.11 KIK47103.1 - 1 8.5 6.9 1.3 8.1 6.9 1.2 1 0 0 1 1 1 0 Cache domain Casein_kappa PF00997.18 KIK47105.1 - 0.74 9.9 7.0 1.4 9.0 7.0 1.6 1 0 0 1 1 1 0 Kappa casein Herpes_V23 PF01802.17 KIK47107.1 - 0.075 12.4 0.1 0.097 12.1 0.1 1.2 1 1 0 1 1 1 0 Herpesvirus VP23 like capsid protein EMP70 PF02990.16 KIK47111.1 - 2.1e-190 633.8 0.7 2.1e-190 633.8 0.7 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 DUF4383 PF14325.6 KIK47112.1 - 0.13 12.5 6.4 0.7 10.2 1.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) Abhydrolase_1 PF00561.20 KIK47113.1 - 5.5e-15 55.7 0.1 1.2e-14 54.6 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK47113.1 - 0.00012 22.7 0.1 0.00015 22.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK47114.1 - 6.9e-11 42.3 0.1 1.1e-10 41.6 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK47114.1 - 0.0075 16.9 0.0 0.0092 16.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ribosom_S12_S23 PF00164.25 KIK47115.1 - 2.4e-49 165.7 1.0 3.1e-49 165.4 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 CTP_transf_1 PF01148.20 KIK47116.1 - 3.1e-70 237.0 21.0 4.5e-70 236.4 21.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family DUF2516 PF10724.9 KIK47116.1 - 0.05 13.9 0.8 0.17 12.2 0.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2516) eIF3_subunit PF08597.10 KIK47116.1 - 0.054 13.4 9.3 0.11 12.4 9.3 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit NARP1 PF12569.8 KIK47116.1 - 0.15 10.9 1.8 0.24 10.3 1.8 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF5345 PF17280.2 KIK47116.1 - 1.8 8.6 4.3 45 4.1 2.1 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5345) CDC45 PF02724.14 KIK47116.1 - 7.9 4.6 6.6 13 4.0 6.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Topoisom_I PF01028.20 KIK47117.1 - 3.3e-100 334.1 4.4 3.3e-100 334.1 4.4 1.8 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KIK47117.1 - 6e-95 316.8 1.7 6e-95 316.8 1.7 2.7 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KIK47117.1 - 1.7e-37 127.2 0.5 6.2e-37 125.4 0.5 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain PIN_5 PF08745.11 KIK47117.1 - 0.0027 17.2 0.5 0.041 13.3 0.0 2.6 2 0 0 2 2 2 1 PINc domain ribonuclease Cep57_CLD_2 PF14197.6 KIK47117.1 - 0.25 11.5 6.4 0.41 10.8 0.5 3.2 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 NDUF_B12 PF08122.12 KIK47118.1 - 6.3e-21 74.2 0.7 6.7e-21 74.1 0.7 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family ESSS PF10183.9 KIK47118.1 - 2.3 8.5 5.5 3.4 7.9 1.1 2.0 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) HAD_2 PF13419.6 KIK47119.1 - 3.5e-06 27.2 0.0 5.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIK47119.1 - 0.0077 16.3 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KIK47119.1 - 0.029 14.7 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PALP PF00291.25 KIK47120.1 - 1.2e-79 267.8 0.0 1.9e-79 267.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KIK47120.1 - 2.6e-38 129.7 0.0 2.4e-22 78.5 0.0 2.6 3 0 0 3 3 3 2 C-terminal regulatory domain of Threonine dehydratase PHD PF00628.29 KIK47121.1 - 2.6e-10 40.0 11.3 4.3e-10 39.3 11.3 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KIK47121.1 - 0.24 11.0 6.6 0.42 10.2 6.6 1.4 1 0 0 1 1 1 0 PHD-finger zf-UDP PF14569.6 KIK47121.1 - 0.27 11.4 2.8 0.65 10.1 2.8 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger Vps8 PF12816.7 KIK47122.1 - 4.2e-68 228.8 0.0 1.3e-67 227.2 0.0 1.8 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KIK47122.1 - 4.3e-07 29.9 0.0 0.011 15.7 0.0 3.2 3 0 0 3 3 3 2 Region in Clathrin and VPS PQQ_3 PF13570.6 KIK47122.1 - 0.011 16.2 1.1 2.4 8.8 0.1 3.0 2 0 0 2 2 2 0 PQQ-like domain SBP_bac_10 PF07596.11 KIK47122.1 - 0.052 13.5 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1559) Mu-like_Com PF10122.9 KIK47122.1 - 0.11 11.9 0.4 0.23 10.9 0.4 1.5 1 0 0 1 1 1 0 Mu-like prophage protein Com DUF3510 PF12022.8 KIK47123.1 - 2.8e-33 115.0 0.0 1.8e-32 112.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) COG2 PF06148.11 KIK47123.1 - 4.7e-26 91.4 5.0 7.1e-26 90.9 3.1 2.4 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 KIK47123.1 - 0.0031 17.6 1.7 0.0081 16.2 0.2 2.5 2 0 0 2 2 2 1 Vps51/Vps67 Zw10 PF06248.13 KIK47123.1 - 0.0076 14.9 0.8 0.0076 14.9 0.8 1.9 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Spc7 PF08317.11 KIK47123.1 - 0.016 14.1 2.6 0.046 12.6 2.6 1.8 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2451 PF10474.9 KIK47123.1 - 0.26 11.0 2.0 33 4.2 0.2 3.6 3 1 0 3 3 3 0 Protein of unknown function C-terminus (DUF2451) Voltage_CLC PF00654.20 KIK47124.1 - 2.9e-93 312.9 19.2 2.9e-93 312.9 19.2 2.0 2 1 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KIK47124.1 - 0.013 15.9 0.1 3.1 8.3 0.0 2.6 2 0 0 2 2 2 0 CBS domain Melibiase_2 PF16499.5 KIK47124.1 - 0.17 11.0 0.4 0.29 10.3 0.4 1.2 1 0 0 1 1 1 0 Alpha galactosidase A LSM PF01423.22 KIK47125.1 - 9.8e-15 54.0 0.2 1.3e-14 53.6 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIK47125.1 - 0.034 14.3 0.0 0.048 13.8 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 KIK47125.1 - 0.039 14.1 0.0 0.053 13.6 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain DUF1674 PF07896.12 KIK47126.1 - 1.6e-15 57.3 2.4 3.5e-15 56.2 2.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) Fungal_trans PF04082.18 KIK47127.1 - 1.4e-16 60.3 0.0 2.8e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK47127.1 - 5.2e-08 32.9 11.6 5.2e-08 32.9 11.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KIK47127.1 - 0.00034 20.7 0.1 0.00078 19.6 0.1 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain ADD_DNMT3 PF17980.1 KIK47127.1 - 0.25 11.4 0.9 0.64 10.1 0.9 1.7 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 F-box-like PF12937.7 KIK47128.1 - 0.00075 19.4 1.6 0.0021 17.9 0.4 2.3 2 0 0 2 2 2 1 F-box-like DnaJ PF00226.31 KIK47131.1 - 2.3e-11 43.7 0.3 3.7e-11 43.0 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain DUF932 PF06067.11 KIK47131.1 - 0.13 12.1 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF932) DUF1771 PF08590.10 KIK47132.1 - 1.6e-16 60.4 2.1 3.5e-16 59.3 2.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 KIK47132.1 - 5.4e-08 33.1 0.0 9.3e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 KIK47133.1 - 3.2e-13 49.8 3.0 3.2e-13 49.8 3.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) SOG2 PF10428.9 KIK47133.1 - 0.21 10.7 10.6 0.25 10.5 10.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIA PF03153.13 KIK47133.1 - 1.7 8.6 7.6 2.1 8.3 7.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 KIK47133.1 - 2.6 9.1 4.2 2.6 9.1 0.7 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) DUF1771 PF08590.10 KIK47135.1 - 5.8e-13 49.0 6.3 1e-12 48.3 6.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 KIK47135.1 - 0.0002 21.6 0.1 0.00043 20.6 0.1 1.6 1 0 0 1 1 1 1 Smr domain DUF4138 PF13595.6 KIK47135.1 - 0.029 13.6 0.1 0.04 13.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4138) DUF1771 PF08590.10 KIK47136.1 - 6.1e-22 77.8 8.0 6.1e-22 77.8 8.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 KIK47136.1 - 1.9e-10 41.0 0.4 4.3e-10 39.8 0.1 1.8 2 0 0 2 2 2 1 Smr domain Tho2 PF11262.8 KIK47136.1 - 0.034 13.3 3.2 0.047 12.9 3.2 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 ART-PolyVal PF18760.1 KIK47136.1 - 0.037 15.1 0.2 0.05 14.6 0.2 1.1 1 0 0 1 1 1 0 ADP-Ribosyltransferase in polyvalent proteins DUF4407 PF14362.6 KIK47136.1 - 0.24 10.7 1.1 0.26 10.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ODC_AZ PF02100.17 KIK47137.1 - 2e-15 56.8 0.0 2.7e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Ribosomal_S5 PF00333.20 KIK47138.1 - 4.2e-29 100.3 0.7 4.2e-29 100.3 0.7 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KIK47138.1 - 1.9e-23 81.7 0.0 3.1e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain p450 PF00067.22 KIK47140.1 - 1.7e-65 221.6 0.0 6.4e-65 219.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Nucleos_tra2_C PF07662.13 KIK47142.1 - 6.6e-66 222.1 7.1 6.6e-66 222.1 7.1 3.0 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KIK47142.1 - 2.1e-19 69.9 2.8 2.1e-19 69.9 2.8 4.1 4 1 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 KIK47142.1 - 0.018 15.3 7.5 0.018 15.3 7.5 3.8 3 1 1 4 4 4 0 Nucleoside recognition WD40 PF00400.32 KIK47143.1 - 2.5e-09 37.6 2.1 0.0031 18.3 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK47143.1 - 5.1e-05 23.5 0.0 2 8.8 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RPA_interact_C PF14768.6 KIK47144.1 - 0.0015 19.1 0.1 0.0025 18.3 0.1 1.3 1 0 0 1 1 1 1 Replication protein A interacting C-terminal MPC PF03650.13 KIK47146.1 - 1e-38 131.8 0.3 1.2e-38 131.7 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Palm_thioest PF02089.15 KIK47147.1 - 3.5e-80 269.4 0.0 4.4e-80 269.0 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PMI_typeI PF01238.21 KIK47149.1 - 3.2e-109 365.6 0.0 3.7e-109 365.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 KIK47149.1 - 0.0018 18.0 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 2 Cupin domain DUF3421 PF11901.8 KIK47151.1 - 2.9e-26 91.7 1.0 1.6e-14 53.8 0.1 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) DUF2076 PF09849.9 KIK47151.1 - 0.00045 20.4 1.9 0.00078 19.6 1.9 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Pex14_N PF04695.13 KIK47151.1 - 0.015 16.0 1.0 0.024 15.3 1.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MerR-DNA-bind PF09278.11 KIK47154.1 - 1.9 9.1 5.2 1.5 9.4 3.0 2.0 2 0 0 2 2 2 0 MerR, DNA binding DUF4637 PF15470.6 KIK47156.1 - 9 6.0 8.2 25 4.6 5.8 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4637) Med1 PF10744.9 KIK47160.1 - 0.00071 18.7 0.0 0.093 11.8 0.0 2.3 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 U3_assoc_6 PF08640.11 KIK47161.1 - 2.7e-31 107.5 5.4 2.4e-30 104.4 4.0 2.7 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KIK47161.1 - 0.00056 20.5 7.5 0.21 12.5 0.3 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat NRDE-2 PF08424.10 KIK47161.1 - 0.0065 15.6 0.0 0.021 13.9 0.0 1.8 2 1 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_15 PF13429.6 KIK47161.1 - 0.0077 15.5 0.5 0.016 14.5 0.5 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Adeno_PIX PF03955.14 KIK47161.1 - 0.11 12.7 0.3 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Arg_decarbox_C PF17944.1 KIK47161.1 - 0.53 10.9 3.3 2.4 8.8 0.5 3.3 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension Glyco_hydro_43 PF04616.14 KIK47162.1 - 3.5e-32 111.9 0.0 4e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 FAD_binding_3 PF01494.19 KIK47163.1 - 9.8e-28 97.4 0.0 1.3e-27 97.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK47163.1 - 5.6e-09 35.7 0.1 0.0013 18.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK47163.1 - 1.3e-05 25.7 0.1 0.16 12.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK47163.1 - 0.0002 21.6 0.0 0.00044 20.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK47163.1 - 0.00069 19.3 0.2 0.13 11.8 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK47163.1 - 0.0078 15.3 0.0 0.019 14.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain SE PF08491.10 KIK47163.1 - 0.015 14.3 0.0 2.3 7.2 0.0 2.7 2 1 1 3 3 3 0 Squalene epoxidase HI0933_like PF03486.14 KIK47163.1 - 0.19 10.4 0.1 0.46 9.1 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein CTK3 PF12243.8 KIK47164.1 - 1.6e-35 121.8 0.0 2.6e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KIK47164.1 - 1.3e-25 89.4 2.5 3.1e-25 88.1 2.5 1.7 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus F-box-like PF12937.7 KIK47165.1 - 7.2e-05 22.6 0.0 0.00026 20.8 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK47165.1 - 0.23 11.4 3.6 0.66 9.9 0.1 3.4 3 0 0 3 3 3 0 F-box domain DEAD PF00270.29 KIK47166.1 - 2.4e-35 121.9 0.1 4e-35 121.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK47166.1 - 7.7e-27 93.8 0.1 1.4e-24 86.6 0.0 2.6 2 1 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KIK47166.1 - 9e-08 32.3 0.0 1.5e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cyclin PF08613.11 KIK47167.1 - 6.9e-29 101.3 0.1 1.8e-28 99.9 0.1 1.7 1 1 1 2 2 2 1 Cyclin Cyclin_N PF00134.23 KIK47167.1 - 0.00011 21.9 0.1 0.00016 21.4 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pkinase PF00069.25 KIK47169.1 - 3.8e-34 118.2 0.0 1.2e-32 113.3 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK47169.1 - 2.6e-18 66.3 0.0 4.6e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK47169.1 - 0.062 13.2 0.2 2.5 7.9 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK47169.1 - 0.13 11.6 0.0 0.33 10.2 0.0 1.5 1 1 0 1 1 1 0 Kinase-like RANK_CRD_2 PF18278.1 KIK47171.1 - 0.017 15.3 0.2 0.042 14.0 0.2 1.7 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Plavaka PF18759.1 KIK47173.1 - 1.1e-36 126.8 0.0 1.7e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase SDA1 PF05285.12 KIK47173.1 - 0.64 9.4 5.4 1.1 8.6 5.4 1.3 1 0 0 1 1 1 0 SDA1 Gpi16 PF04113.14 KIK47174.1 - 1.1e-69 235.4 0.0 1.1e-68 232.1 0.0 1.9 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component DUF677 PF05055.12 KIK47175.1 - 0.074 11.9 0.0 0.12 11.2 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF677) Got1 PF04178.12 KIK47178.1 - 6.1e-19 68.5 16.8 7.8e-19 68.2 16.8 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family CPP1-like PF11833.8 KIK47178.1 - 0.69 9.5 3.4 0.87 9.2 3.4 1.1 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like MFS_1 PF07690.16 KIK47179.1 - 4.2e-15 55.5 41.3 1.6e-14 53.7 39.3 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK47179.1 - 1 8.1 28.4 0.0076 15.1 12.5 2.7 2 1 1 3 3 3 0 Sugar (and other) transporter WD40 PF00400.32 KIK47181.1 - 2e-43 145.5 26.8 6.1e-09 36.4 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK47181.1 - 1.6e-09 37.9 1.1 0.037 14.3 0.0 4.9 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK47181.1 - 4.9e-05 22.2 4.5 0.0098 14.6 0.1 3.6 2 1 2 4 4 4 2 Nucleoporin Nup120/160 DUF1513 PF07433.11 KIK47181.1 - 0.00028 20.1 0.0 0.077 12.1 0.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF1513) PD40 PF07676.12 KIK47181.1 - 0.0012 18.7 3.1 4.9 7.2 0.0 4.9 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KIK47181.1 - 0.0062 15.1 0.0 0.48 8.9 0.1 2.4 2 1 0 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.5 KIK47181.1 - 0.19 11.0 0.0 17 4.6 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain IU_nuc_hydro PF01156.19 KIK47182.1 - 3.5e-53 181.1 0.0 4.6e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase bZIP_1 PF00170.21 KIK47183.1 - 0.014 15.5 5.6 0.024 14.7 5.6 1.3 1 0 0 1 1 1 0 bZIP transcription factor Allantoicase PF03561.15 KIK47184.1 - 3.5e-82 273.5 0.0 3.5e-42 143.8 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat Plavaka PF18759.1 KIK47186.1 - 2.4e-124 414.8 0.0 3.8e-124 414.1 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2 PF00096.26 KIK47186.1 - 0.067 13.7 0.7 0.34 11.4 0.7 2.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK47186.1 - 0.078 13.9 0.7 0.57 11.2 0.7 2.7 1 0 0 1 1 1 0 C2H2-type zinc finger Pyr_redox PF00070.27 KIK47187.1 - 0.0015 19.1 0.0 0.015 15.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK47187.1 - 0.0017 18.5 0.0 0.0035 17.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIK47187.1 - 0.0064 15.8 0.0 0.021 14.1 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIK47187.1 - 0.032 13.5 0.0 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK47187.1 - 0.18 10.5 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Dabb PF07876.12 KIK47188.1 - 2e-20 73.2 0.0 2.2e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Dabb PF07876.12 KIK47189.1 - 1.8e-21 76.5 0.0 2e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain ICMT PF04140.14 KIK47191.1 - 6.5e-05 23.3 0.1 0.00018 21.9 0.1 1.9 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK47191.1 - 0.0042 17.5 0.6 0.011 16.1 0.2 2.0 2 1 0 2 2 2 1 Phospholipid methyltransferase DGF-1_5 PF11038.8 KIK47191.1 - 0.025 13.9 0.4 0.043 13.2 0.2 1.3 1 1 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 DUF2209 PF09974.9 KIK47191.1 - 0.08 13.3 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) ICMT PF04140.14 KIK47192.1 - 1.4e-06 28.6 0.2 3.7e-06 27.3 0.2 1.7 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK47192.1 - 9.7e-05 22.7 2.0 0.00011 22.5 0.2 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 KIK47192.1 - 0.0062 16.1 1.0 0.0089 15.6 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 KIK47192.1 - 0.02 13.7 0.0 0.036 12.8 0.0 1.5 1 1 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 KIK47192.1 - 0.044 13.8 0.3 0.063 13.3 0.3 1.4 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase 7tm_7 PF08395.12 KIK47192.1 - 0.099 11.8 1.0 0.14 11.3 1.0 1.2 1 0 0 1 1 1 0 7tm Chemosensory receptor SelP_N PF04592.14 KIK47193.1 - 0.13 11.6 1.0 0.3 10.5 1.0 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PROCN PF08083.11 KIK47194.1 - 4.1e-232 770.1 10.6 6.2e-232 769.5 9.1 1.9 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KIK47194.1 - 1e-126 421.2 0.4 2e-126 420.3 0.4 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KIK47194.1 - 1.2e-87 291.9 2.3 1.2e-87 291.9 2.3 2.4 3 0 0 3 3 3 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KIK47194.1 - 3.6e-85 283.5 2.2 3.6e-85 283.5 2.2 2.8 3 0 0 3 3 3 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KIK47194.1 - 3e-73 244.2 0.1 6.6e-73 243.1 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 KIK47194.1 - 4e-46 155.3 0.3 8.6e-46 154.2 0.3 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 KIK47194.1 - 1.3e-39 134.9 0.0 2.9e-39 133.8 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 KIK47194.1 - 0.0059 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease NIR_SIR_ferr PF03460.17 KIK47195.1 - 0.009 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain SIKE PF05769.11 KIK47196.1 - 1.3e-06 28.4 9.5 6.1e-05 23.0 4.4 2.2 2 0 0 2 2 2 2 SIKE family Vps5 PF09325.10 KIK47196.1 - 0.0069 16.0 0.6 0.014 15.0 0.2 1.8 2 0 0 2 2 2 1 Vps5 C terminal like TACC_C PF05010.14 KIK47196.1 - 0.01 15.7 0.6 0.019 14.8 0.6 1.4 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Nsp1_C PF05064.13 KIK47196.1 - 0.016 15.0 0.5 0.028 14.2 0.0 1.8 2 0 0 2 2 2 0 Nsp1-like C-terminal region FAM184 PF15665.5 KIK47196.1 - 0.035 13.9 3.0 0.06 13.1 3.0 1.4 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B SseC PF04888.12 KIK47196.1 - 0.07 12.7 0.3 0.1 12.2 0.3 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Phage_Mu_Gam PF07352.12 KIK47196.1 - 0.17 11.8 2.5 0.1 12.5 0.6 1.7 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Cnn_1N PF07989.11 KIK47196.1 - 0.22 11.7 0.3 0.22 11.7 0.3 2.4 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 OmpH PF03938.14 KIK47196.1 - 0.27 11.6 3.9 0.28 11.5 2.6 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Mce4_CUP1 PF11887.8 KIK47196.1 - 1.3 8.5 3.6 0.59 9.5 1.5 1.5 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative YabA PF06156.13 KIK47196.1 - 5.3 7.7 5.9 9.3 7.0 1.2 3.0 3 1 0 3 3 3 0 Initiation control protein YabA PHD PF00628.29 KIK47198.1 - 9.6e-07 28.6 6.4 4.5e-06 26.4 6.4 2.2 1 1 0 1 1 1 1 PHD-finger C1_1 PF00130.22 KIK47198.1 - 0.16 11.9 7.8 0.037 13.9 3.5 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 KIK47198.1 - 0.32 10.6 10.1 0.51 9.9 0.2 3.2 3 0 0 3 3 3 0 PHD-finger C1_2 PF03107.16 KIK47198.1 - 4.1 7.8 8.3 3.6 8.0 6.0 2.1 2 0 0 2 2 2 0 C1 domain F-actin_cap_A PF01267.17 KIK47200.1 - 1.4e-97 326.3 0.0 1.6e-97 326.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit ICL PF00463.21 KIK47201.1 - 6.7e-256 849.8 0.1 7.5e-256 849.7 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KIK47201.1 - 1.5e-09 37.7 0.0 2.5e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Glycos_transf_4 PF00953.21 KIK47202.1 - 2.3e-29 102.4 7.2 2.3e-29 102.4 7.2 2.6 3 0 0 3 3 3 1 Glycosyl transferase family 4 SET PF00856.28 KIK47203.1 - 1.8e-11 44.7 0.6 6.7e-10 39.6 0.2 2.6 2 1 0 2 2 2 1 SET domain dCMP_cyt_deam_1 PF00383.23 KIK47203.1 - 1.8e-07 30.9 0.0 3.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KIK47203.1 - 5.5e-05 22.9 0.1 0.00012 21.8 0.1 1.5 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KIK47203.1 - 0.17 11.9 0.0 0.86 9.7 0.0 2.0 2 0 0 2 2 2 0 Bd3614-like deaminase Malic_M PF03949.15 KIK47204.1 - 1.1e-89 300.2 0.0 1.4e-89 299.8 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KIK47204.1 - 2.6e-66 222.9 0.0 5.5e-66 221.8 0.0 1.6 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF3310 PF11753.8 KIK47204.1 - 0.054 13.7 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknwon function (DUF3310) MRP-L20 PF12824.7 KIK47205.1 - 1.5e-24 87.0 8.9 3.2e-24 85.9 8.9 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 KIK47205.1 - 0.084 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Neugrin HTH_7 PF02796.15 KIK47205.1 - 0.18 11.9 0.0 0.42 10.7 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain of resolvase Ubie_methyltran PF01209.18 KIK47206.1 - 1.6e-77 259.9 0.0 2.1e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KIK47206.1 - 5.8e-13 49.4 0.0 1.1e-12 48.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK47206.1 - 6e-10 39.1 0.0 1.6e-09 37.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK47206.1 - 7.9e-10 39.3 0.0 1.3e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK47206.1 - 2.5e-09 37.2 0.0 3.7e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK47206.1 - 6.9e-09 36.3 0.0 1.1e-08 35.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 KIK47206.1 - 0.18 11.4 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Cullin PF00888.22 KIK47207.1 - 4.5e-186 620.1 17.8 7.1e-186 619.5 17.8 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KIK47207.1 - 1.2e-26 92.5 2.0 4.5e-26 90.7 2.0 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain Phage_rep_O PF04492.13 KIK47207.1 - 0.0038 17.8 0.1 0.013 16.1 0.1 1.9 1 0 0 1 1 1 1 Bacteriophage replication protein O Rrf2 PF02082.20 KIK47207.1 - 0.22 11.9 0.8 1 9.8 0.5 2.3 3 0 0 3 3 3 0 Transcriptional regulator HAT_KAT11 PF08214.11 KIK47208.1 - 1.1e-45 156.5 0.0 1.5e-45 156.0 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Ycf1 PF05758.12 KIK47208.1 - 0.39 8.5 0.7 0.51 8.1 0.7 1.1 1 0 0 1 1 1 0 Ycf1 Filament PF00038.21 KIK47209.1 - 0.044 13.4 6.6 0.064 12.8 6.6 1.1 1 0 0 1 1 1 0 Intermediate filament protein DUF5394 PF17372.2 KIK47209.1 - 0.23 11.0 2.2 0.35 10.4 2.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5394) GST_N PF02798.20 KIK47210.1 - 1.6e-11 44.4 0.0 2.5e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIK47210.1 - 1.3e-09 38.3 0.0 2.2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK47210.1 - 4.6e-09 36.4 0.0 1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KIK47210.1 - 2.5e-08 34.1 0.0 4.7e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIK47210.1 - 0.00098 19.3 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK47210.1 - 0.0068 16.4 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 KIK47211.1 - 3.1e-30 105.3 39.1 4.6e-30 104.7 39.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK47211.1 - 6.2e-07 28.6 22.8 8.4e-07 28.2 22.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KIK47211.1 - 7.7e-06 24.6 3.1 7.7e-06 24.6 3.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) C_GCAxxG_C_C PF09719.10 KIK47211.1 - 0.39 11.0 1.5 0.79 10.0 1.5 1.4 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) DUF3341 PF11821.8 KIK47211.1 - 2.3 7.8 8.0 0.29 10.8 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3341) MFS_1 PF07690.16 KIK47213.1 - 5e-38 130.9 66.6 1.4e-31 109.8 36.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK47213.1 - 2.7e-10 39.7 23.1 7.7e-10 38.2 23.1 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KIK47213.1 - 0.00031 19.3 1.9 0.00061 18.3 1.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Torsin PF06309.11 KIK47215.1 - 0.026 14.6 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Torsin adh_short_C2 PF13561.6 KIK47216.1 - 2.5e-40 138.5 2.0 6.2e-39 133.9 2.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK47216.1 - 2.5e-38 131.5 1.0 8.4e-38 129.8 1.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK47216.1 - 4e-07 30.1 0.9 8.4e-07 29.1 0.4 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KIK47216.1 - 0.0012 18.3 0.1 0.86 9.0 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.27 KIK47216.1 - 0.0012 19.3 0.7 0.011 16.3 0.8 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KIK47216.1 - 0.11 12.2 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 KIK47217.1 - 3.1e-44 151.7 0.3 3.6e-43 148.2 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK47217.1 - 2.2e-07 30.4 0.2 0.0054 16.0 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIK47217.1 - 8.1e-07 28.7 0.2 1.1e-05 25.0 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 KIK47217.1 - 1.5e-06 28.0 11.3 6.9e-06 25.9 4.8 3.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KIK47217.1 - 2e-05 23.9 7.2 5.8e-05 22.3 0.8 2.7 3 0 0 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.14 KIK47217.1 - 0.00042 19.1 2.1 0.56 8.9 0.0 2.8 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.6 KIK47217.1 - 0.0023 18.1 1.1 0.0077 16.4 1.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIK47217.1 - 0.0086 15.4 0.4 0.23 10.7 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK47217.1 - 0.13 12.9 1.2 10 6.8 0.1 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Sas10 PF09368.10 KIK47218.1 - 3.5e-26 91.5 6.9 3.5e-26 91.5 6.9 3.2 4 0 0 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KIK47218.1 - 2.2e-06 28.2 0.5 1.3e-05 25.8 0.5 2.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Fungal_trans PF04082.18 KIK47219.1 - 3.2e-05 23.1 0.0 6.9e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK47219.1 - 0.0008 19.5 6.3 0.0016 18.5 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tom22 PF04281.13 KIK47220.1 - 9.7e-39 132.3 1.6 1.1e-38 132.1 1.6 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 NAD_binding_10 PF13460.6 KIK47221.1 - 3.5e-12 46.6 0.0 5.2e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIK47221.1 - 1.1e-11 44.7 0.0 1.5e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KIK47221.1 - 1.1e-10 41.1 0.0 4.8e-09 35.7 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KIK47221.1 - 2e-10 40.6 0.0 9.6e-10 38.3 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIK47221.1 - 9e-10 38.0 0.0 1.7e-09 37.1 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIK47221.1 - 1.2e-06 27.9 0.2 0.0018 17.5 0.0 3.0 1 1 2 3 3 3 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KIK47221.1 - 0.00017 21.1 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KIK47221.1 - 0.0018 17.7 0.0 0.0034 16.9 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK47221.1 - 0.0077 15.8 0.0 0.016 14.8 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KIK47221.1 - 0.016 14.3 0.0 0.042 13.0 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.10 KIK47221.1 - 0.043 13.7 0.0 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 KR domain DUF2462 PF09495.10 KIK47222.1 - 2.9e-21 76.0 13.5 3.6e-21 75.7 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) HTH_Tnp_Tc5 PF03221.16 KIK47223.1 - 2.5e-17 62.7 0.4 4.2e-17 61.9 0.4 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain AOX PF01786.17 KIK47226.1 - 7.2e-98 326.4 0.0 8.8e-98 326.1 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase Peptidase_S66C PF17676.1 KIK47226.1 - 0.037 14.6 0.1 0.095 13.2 0.0 1.7 2 0 0 2 2 2 0 LD-carboxypeptidase C-terminal domain Tn7_TnsC_Int PF11426.8 KIK47226.1 - 0.14 12.3 0.0 0.49 10.6 0.0 2.0 1 0 0 1 1 1 0 Tn7 transposition regulator TnsC PH_4 PF15404.6 KIK47227.1 - 4.1e-18 65.8 0.7 2.5e-08 33.9 0.0 3.0 2 1 1 3 3 3 2 Pleckstrin homology domain zf-Nse PF11789.8 KIK47228.1 - 7.1e-14 51.4 0.0 1.2e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 KIK47228.1 - 8.6e-05 22.6 0.0 0.00074 19.6 0.0 2.2 2 0 0 2 2 2 1 U-box domain zf-C3HC4_2 PF13923.6 KIK47228.1 - 0.00012 21.8 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK47228.1 - 0.0012 18.8 0.1 0.0021 18.0 0.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIK47228.1 - 0.0076 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 KIK47228.1 - 0.019 14.7 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF5446 PF17522.2 KIK47228.1 - 0.1 12.8 1.0 0.32 11.2 1.0 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5446) DUF2203 PF09969.9 KIK47228.1 - 0.48 11.1 2.3 0.36 11.6 0.3 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Ribosom_S12_S23 PF00164.25 KIK47229.1 - 8.8e-33 112.3 1.7 1.2e-32 111.9 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 MRP-L47 PF06984.13 KIK47231.1 - 1.8e-18 66.4 0.3 4.1e-18 65.3 0.3 1.7 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 KIK47231.1 - 0.016 15.2 1.8 0.016 15.2 1.8 3.0 2 1 0 2 2 2 0 Ribosomal L29 protein Complex1_LYR PF05347.15 KIK47232.1 - 1.6e-08 34.5 0.5 2.3e-08 34.0 0.5 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KIK47232.1 - 0.11 13.3 0.4 0.14 12.9 0.4 1.3 1 1 0 1 1 1 0 Complex1_LYR-like SQS_PSY PF00494.19 KIK47233.1 - 3.3e-52 177.6 0.5 3.8e-52 177.4 0.5 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase ROS_MUCR PF05443.11 KIK47234.1 - 0.13 12.3 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein MFS_1 PF07690.16 KIK47235.1 - 5.2e-32 111.1 34.2 5.2e-32 111.1 34.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KIK47235.1 - 0.019 14.8 0.8 0.15 11.9 0.2 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) UNC-50 PF05216.13 KIK47235.1 - 0.17 11.4 0.0 0.17 11.4 0.0 2.9 3 0 0 3 3 3 0 UNC-50 family vATP-synt_AC39 PF01992.16 KIK47236.1 - 1.2e-116 389.9 0.5 1.4e-116 389.7 0.5 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit TLP1_add_C PF18313.1 KIK47236.1 - 0.06 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain EHN PF06441.12 KIK47237.1 - 7.2e-32 110.0 4.3 1.1e-31 109.4 0.0 2.5 2 1 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KIK47237.1 - 4.3e-12 46.2 0.2 7.3e-12 45.5 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK47237.1 - 0.0012 19.5 8.1 0.01 16.4 8.1 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.12 KIK47238.1 - 1.7e-34 118.5 1.1 1e-33 116.0 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KIK47238.1 - 5.3e-13 49.2 0.0 8.8e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK47238.1 - 0.00016 22.4 3.9 0.00048 20.8 3.9 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family polyprenyl_synt PF00348.17 KIK47239.1 - 4e-54 183.4 0.0 1.6e-28 99.5 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase MFS_1 PF07690.16 KIK47240.1 - 9.8e-10 37.9 50.8 1.7e-08 33.8 25.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 KIK47240.1 - 3.8 7.3 4.5 1.9 8.3 0.5 2.5 1 1 0 2 2 2 0 Bacteriophage holin family, superfamily II-like CRAL_TRIO PF00650.20 KIK47241.1 - 1.7e-27 96.1 0.0 2.4e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK47241.1 - 9.3e-09 35.3 0.0 2.4e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain zf-CCHC_3 PF13917.6 KIK47244.1 - 2.6e-17 62.5 0.1 2.6e-17 62.5 0.1 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 KIK47244.1 - 0.051 13.7 0.4 0.09 12.9 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Plasmodium_Vir PF05795.11 KIK47244.1 - 1.3 8.3 9.5 1.8 7.9 9.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Macoilin PF09726.9 KIK47244.1 - 1.4 7.4 16.3 1.4 7.4 16.3 1.1 1 0 0 1 1 1 0 Macoilin family TFIIF_alpha PF05793.12 KIK47244.1 - 5.4 5.5 24.7 6.2 5.3 24.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Smg8_Smg9 PF10220.9 KIK47244.1 - 6.4 4.9 9.1 5.7 5.1 9.1 1.1 1 0 0 1 1 1 0 Smg8_Smg9 DHHW PF14286.6 KIK47244.1 - 6.5 6.0 6.4 7.6 5.7 6.4 1.1 1 0 0 1 1 1 0 DHHW protein ATP-synt_C PF00137.21 KIK47245.1 - 2.8e-29 101.2 33.8 2e-17 63.3 12.1 2.2 2 0 0 2 2 2 2 ATP synthase subunit C DUF4064 PF13273.6 KIK47245.1 - 1.3 9.4 13.3 2.5 8.4 0.9 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) NapE PF06796.11 KIK47245.1 - 3.5 7.2 7.4 2.9 7.5 1.5 2.5 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE ATP-synt_J PF04911.12 KIK47245.1 - 5.3 6.7 6.8 4.8 6.8 0.6 2.6 2 0 0 2 2 2 0 ATP synthase j chain Ribosomal_L6 PF00347.23 KIK47246.1 - 7.8e-23 81.0 0.0 6.9e-11 42.7 0.0 2.5 2 1 0 2 2 2 2 Ribosomal protein L6 AA_permease_2 PF13520.6 KIK47247.1 - 7.7e-53 179.8 53.7 9.7e-53 179.5 53.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIK47247.1 - 9.2e-14 50.9 52.9 1.7e-13 50.0 52.9 1.3 1 1 0 1 1 1 1 Amino acid permease Patatin PF01734.22 KIK47247.1 - 0.0073 16.5 0.8 0.011 15.9 0.8 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3481 PF11980.8 KIK47247.1 - 0.47 10.2 0.0 0.47 10.2 0.0 3.6 5 0 0 5 5 5 0 C-terminal domain of neuropilin glycoprotein tRNA_bind PF01588.20 KIK47248.1 - 4.6e-28 97.2 0.0 9.3e-28 96.2 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 KIK47248.1 - 6e-06 26.4 0.0 6e-06 26.4 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK47248.1 - 0.00085 19.5 0.0 0.0022 18.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK47248.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain F-box-like PF12937.7 KIK47249.1 - 2.9e-08 33.5 1.4 3.9e-08 33.1 0.2 2.0 2 0 0 2 2 2 1 F-box-like DUF4611 PF15387.6 KIK47249.1 - 1.6 9.0 6.5 0.69 10.2 3.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DIOX_N PF14226.6 KIK47250.1 - 6.1e-26 91.5 0.1 9.2e-26 90.9 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK47250.1 - 4.2e-15 56.1 0.0 9.1e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ComA PF02679.15 KIK47250.1 - 0.095 12.2 0.0 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) Chlor_dismutase PF06778.12 KIK47250.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Chlorite dismutase CBFD_NFYB_HMF PF00808.23 KIK47251.1 - 1.6e-08 34.7 0.0 3.3e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK47251.1 - 0.0037 17.6 1.4 0.041 14.2 0.0 2.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 HSP20 PF00011.21 KIK47252.1 - 1.8e-14 53.7 0.1 6.9e-12 45.4 0.1 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIK47252.1 - 7.1e-09 35.1 0.0 2.6e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 HSP20-like domain found in ArsA GvpH PF05455.11 KIK47252.1 - 0.026 14.6 0.1 0.071 13.2 0.0 1.6 1 1 1 2 2 2 0 GvpH FKBP26_C PF18046.1 KIK47252.1 - 0.035 14.2 0.1 1.6 8.9 0.0 2.2 2 0 0 2 2 2 0 FKBP26_C-terminal DUF1325 PF07039.11 KIK47253.1 - 5.2e-39 133.4 0.0 8e-39 132.7 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 KIK47253.1 - 0.013 15.3 0.1 0.042 13.7 0.0 1.9 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 KIK47253.1 - 0.017 15.5 0.0 2.5 8.7 0.0 2.5 2 0 0 2 2 2 0 Agenet domain LBR_tudor PF09465.10 KIK47253.1 - 0.026 14.3 0.2 0.09 12.6 0.0 2.0 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain Translin PF01997.16 KIK47254.1 - 8.8e-44 149.9 0.0 9.5e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 Translin family SEN1_N PF12726.7 KIK47255.1 - 2e-154 515.7 1.8 3.1e-154 515.1 1.8 1.3 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KIK47255.1 - 3.5e-71 240.1 3.9 3.5e-71 240.1 3.9 2.2 2 1 0 2 2 1 1 AAA domain AAA_12 PF13087.6 KIK47255.1 - 2.7e-57 193.6 0.0 1.1e-56 191.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KIK47255.1 - 1.2e-08 35.4 3.9 9.9e-05 22.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 KIK47255.1 - 3.2e-07 30.2 6.1 0.00014 21.6 0.1 3.0 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 KIK47255.1 - 0.00025 20.9 1.5 0.57 9.9 0.2 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KIK47255.1 - 0.00076 19.1 2.2 0.0065 16.0 2.2 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_23 PF13476.6 KIK47255.1 - 0.00088 19.8 0.4 0.0022 18.6 0.4 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KIK47255.1 - 0.0043 17.1 0.0 0.015 15.3 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KIK47255.1 - 0.0058 16.5 0.2 1.5 8.7 0.0 2.7 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.6 KIK47255.1 - 0.051 13.9 0.2 0.46 10.8 0.0 2.6 1 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIK47255.1 - 0.079 13.3 0.3 0.56 10.6 0.1 2.5 1 1 0 1 1 1 0 AAA ATPase domain HCMV_UL139 PF12507.8 KIK47255.1 - 0.12 12.7 1.1 0.48 10.8 1.1 2.0 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein AAA_25 PF13481.6 KIK47255.1 - 0.12 11.9 0.1 0.46 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KIK47255.1 - 0.16 12.4 1.1 0.54 10.7 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1216 PF06746.11 KIK47255.1 - 0.34 10.9 5.5 0.16 12.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) DUF16 PF01519.16 KIK47255.1 - 0.6 10.6 3.0 2.4 8.7 3.0 2.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 OB_NTP_bind PF07717.16 KIK47256.1 - 2.5e-20 72.6 0.0 4e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIK47257.1 - 5.8e-08 33.1 0.0 3.2e-06 27.5 0.0 2.7 1 1 1 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KIK47258.1 - 0.02 15.1 2.5 0.095 13.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 KIK47258.1 - 0.029 13.7 0.1 0.068 12.5 0.1 1.6 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 KIK47258.1 - 0.038 13.1 1.0 0.1 11.7 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein DEAD PF00270.29 KIK47258.1 - 0.078 12.7 0.5 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_23 PF13476.6 KIK47258.1 - 0.11 13.0 0.1 0.11 13.0 0.1 2.7 2 1 0 2 2 2 0 AAA domain DUF3878 PF12994.7 KIK47258.1 - 0.79 9.1 4.3 1.3 8.4 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3878) Glyco_hydro_71 PF03659.14 KIK47259.1 - 5.9e-129 430.2 3.9 6.9e-129 429.9 3.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Fcf2 PF08698.11 KIK47260.1 - 3.7e-29 101.0 0.0 8.2e-29 99.9 0.0 1.6 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing SAP PF02037.27 KIK47261.1 - 0.0062 16.3 0.7 0.065 13.0 0.2 2.2 2 0 0 2 2 2 1 SAP domain HLH PF00010.26 KIK47262.1 - 0.012 15.6 0.2 0.012 15.6 0.2 1.6 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain AMPKBI PF04739.15 KIK47264.1 - 1.8e-24 85.8 1.5 2.5e-23 82.1 1.5 2.7 1 1 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 KIK47264.1 - 7.7e-20 70.9 0.0 1.5e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DUF3915 PF13054.6 KIK47264.1 - 0.017 15.1 1.8 0.032 14.2 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) A_deaminase PF00962.22 KIK47265.1 - 3.4e-121 404.6 0.3 4.7e-121 404.1 0.3 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF2235 PF09994.9 KIK47266.1 - 3.7e-84 282.5 0.0 4.6e-84 282.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Pkinase PF00069.25 KIK47270.1 - 4.7e-68 229.4 0.0 6.2e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK47270.1 - 1.7e-36 125.9 0.0 1.3e-35 123.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KIK47270.1 - 0.0016 17.6 0.1 0.0029 16.7 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 KIK47270.1 - 0.006 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIK47270.1 - 0.0088 14.9 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KIK47270.1 - 0.042 12.8 0.1 0.077 11.9 0.1 1.4 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KIK47270.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Avl9 PF09794.9 KIK47271.1 - 1.5e-124 415.5 0.0 2e-124 415.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 KIK47271.1 - 1.9e-06 27.8 0.0 0.046 13.7 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 KIK47271.1 - 3e-06 27.0 0.6 0.013 15.1 0.2 2.7 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Ribonuc_red_lgC PF02867.15 KIK47273.1 - 2.1e-180 600.7 0.0 2.9e-180 600.3 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KIK47273.1 - 8.7e-24 83.3 0.1 1.8e-23 82.3 0.1 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KIK47273.1 - 6.7e-17 61.8 0.1 1.7e-16 60.6 0.1 1.7 1 0 0 1 1 1 1 ATP cone domain BTB PF00651.31 KIK47275.1 - 0.00047 20.4 0.0 0.0011 19.1 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain Aldo_ket_red PF00248.21 KIK47276.1 - 2.2e-41 142.0 0.2 8.6e-40 136.8 0.2 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family T2SSM PF04612.12 KIK47276.1 - 0.09 12.8 0.0 3.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M LeuA_dimer PF08502.10 KIK47276.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 LeuA allosteric (dimerisation) domain Aldo_ket_red PF00248.21 KIK47277.1 - 2e-41 142.1 0.1 7.3e-40 137.0 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Peripla_BP_6 PF13458.6 KIK47277.1 - 0.063 12.9 0.0 0.19 11.4 0.0 1.7 1 1 0 1 1 1 0 Periplasmic binding protein Rad51 PF08423.11 KIK47278.1 - 3.8e-07 29.6 0.0 6.2e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Rad51 HAP1_N PF04849.13 KIK47279.1 - 0.063 12.5 23.8 3.3 6.8 0.0 3.3 3 0 0 3 3 3 0 HAP1 N-terminal conserved region PRKG1_interact PF15898.5 KIK47279.1 - 1.4 9.8 0.0 1.4 9.8 0.0 5.3 5 2 1 6 6 6 0 cGMP-dependent protein kinase interacting domain HAUS-augmin3 PF14932.6 KIK47279.1 - 2 7.9 24.5 3.2 7.3 3.3 3.5 3 1 0 3 3 3 0 HAUS augmin-like complex subunit 3 TolA_bind_tri PF16331.5 KIK47279.1 - 3.8 7.7 21.5 0.043 13.9 1.9 4.3 3 1 1 4 4 4 0 TolA binding protein trimerisation TSC22 PF01166.18 KIK47279.1 - 4.5 7.7 8.4 35 4.8 0.7 3.8 3 0 0 3 3 3 0 TSC-22/dip/bun family YabA PF06156.13 KIK47279.1 - 4.5 8.0 17.1 35 5.1 0.3 4.2 3 1 1 4 4 4 0 Initiation control protein YabA ZapB PF06005.12 KIK47279.1 - 10 6.7 28.9 4.2 7.9 2.2 4.4 4 0 0 4 4 4 0 Cell division protein ZapB SLX9 PF15341.6 KIK47281.1 - 3.9e-19 69.3 3.9 5.4e-19 68.9 3.9 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 SAGA-Tad1 PF12767.7 KIK47281.1 - 0.032 14.0 2.2 0.04 13.7 2.2 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF3751 PF12571.8 KIK47281.1 - 0.067 13.3 0.3 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 Phage tail-collar fibre protein IHO1 PF15771.5 KIK47281.1 - 0.5 9.1 6.5 1.3 7.7 2.8 2.0 1 1 1 2 2 2 0 Interactor of HORMAD1 protein 1 EamA PF00892.20 KIK47282.1 - 1e-08 35.5 32.6 1.2e-05 25.5 4.2 3.0 3 0 0 3 3 3 2 EamA-like transporter family SLC35F PF06027.12 KIK47282.1 - 0.00037 20.1 10.6 0.00037 20.1 10.6 2.8 2 1 1 3 3 3 1 Solute carrier family 35 Pho86 PF11124.8 KIK47282.1 - 4.5 6.7 5.2 0.37 10.2 0.3 1.7 2 0 0 2 2 2 0 Inorganic phosphate transporter Pho86 Nefa_Nip30_N PF10187.9 KIK47284.1 - 1.4e-30 105.7 9.7 1.4e-30 105.7 9.7 2.2 2 0 0 2 2 2 2 N-terminal domain of NEFA-interacting nuclear protein NIP30 Es2 PF09751.9 KIK47285.1 - 1.4e-87 295.3 8.2 1.8e-87 294.9 8.2 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 NUDE_C PF04880.13 KIK47286.1 - 1.6e-06 28.7 26.5 1.6e-06 28.7 26.5 5.2 3 3 1 5 5 5 1 NUDE protein, C-terminal conserved region TPR_MLP1_2 PF07926.12 KIK47286.1 - 0.76 9.8 27.9 2.1 8.4 2.6 3.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein PRKG1_interact PF15898.5 KIK47286.1 - 2.7 8.9 23.7 0.14 13.0 9.5 3.1 2 1 2 4 4 4 0 cGMP-dependent protein kinase interacting domain DUF4407 PF14362.6 KIK47286.1 - 5 6.4 11.3 1.9 7.8 8.5 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) EXOSC1 PF10447.9 KIK47287.1 - 1.1e-18 67.8 2.9 3.3e-13 50.2 0.3 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KIK47287.1 - 0.057 13.2 0.6 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region 2-oxoacid_dh PF00198.23 KIK47288.1 - 3.6e-81 272.0 0.0 4.6e-81 271.7 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KIK47288.1 - 2.2e-19 69.1 0.5 2.2e-19 69.1 0.5 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 KIK47288.1 - 1.9e-14 53.7 0.2 4.9e-14 52.4 0.2 1.8 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.8 KIK47288.1 - 0.047 14.2 0.0 0.14 12.6 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3614) Jun PF03957.13 KIK47289.1 - 0.14 12.0 0.7 0.23 11.3 0.7 1.3 1 0 0 1 1 1 0 Jun-like transcription factor Peptidase_M22 PF00814.25 KIK47290.1 - 1.4e-83 280.7 0.0 1.7e-83 280.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KIK47290.1 - 0.19 11.4 0.0 0.72 9.5 0.0 1.8 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus Glyco_transf_8 PF01501.20 KIK47291.1 - 9.4e-18 64.7 0.0 2.5e-17 63.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KIK47291.1 - 0.00025 20.5 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_24 PF18404.1 KIK47291.1 - 0.0073 15.8 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Ribosomal_S28e PF01200.18 KIK47292.1 - 2.6e-31 107.4 1.1 3.1e-31 107.1 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e LIAS_N PF16881.5 KIK47295.1 - 1.6e-25 89.7 0.0 4.3e-25 88.2 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KIK47295.1 - 1.1e-15 58.4 0.0 2.4e-15 57.3 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Spore_GerAC PF05504.11 KIK47295.1 - 0.099 12.9 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal SapB_1 PF05184.15 KIK47295.1 - 0.11 12.5 0.7 7.2 6.7 0.1 2.6 2 0 0 2 2 2 0 Saposin-like type B, region 1 PEX11 PF05648.14 KIK47296.1 - 7.8e-52 175.9 0.6 8.8e-52 175.8 0.6 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Lyase_1 PF00206.20 KIK47297.1 - 1.2e-120 402.6 0.0 1.6e-120 402.2 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KIK47297.1 - 1.4e-19 70.2 0.1 2.8e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 Fumarase C C-terminus SNF2_N PF00176.23 KIK47298.1 - 4.2e-65 219.8 1.4 6.9e-65 219.0 1.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KIK47298.1 - 6.2e-50 169.0 16.9 1.6e-49 167.7 16.9 1.8 1 0 0 1 1 1 1 DNA-binding domain Helicase_C PF00271.31 KIK47298.1 - 8.6e-16 58.3 0.0 1.9e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK47298.1 - 2.3e-06 27.7 0.0 5.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KIK47298.1 - 7.4e-06 25.3 0.2 6e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 HA2 PF04408.23 KIK47299.1 - 3.9e-16 59.3 0.0 1.4e-15 57.5 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KIK47299.1 - 1.4e-15 57.6 0.1 4e-15 56.1 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KIK47299.1 - 9e-09 35.6 0.0 2e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KIK47299.1 - 3e-06 27.6 0.1 1.1e-05 25.7 0.1 2.0 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KIK47299.1 - 0.091 13.3 0.1 0.29 11.6 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Rad17 PF03215.15 KIK47299.1 - 0.14 12.1 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain Ribosomal_L22e PF01776.17 KIK47300.1 - 3.1e-48 162.7 0.4 3.7e-48 162.4 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DKCLD PF08068.12 KIK47301.1 - 5.6e-32 109.6 0.3 4.9e-31 106.6 0.5 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 KIK47301.1 - 1.7e-23 82.5 0.7 3.8e-23 81.4 0.7 1.7 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 KIK47301.1 - 2.3e-23 83.2 0.2 6.4e-20 72.0 0.2 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 KIK47301.1 - 1.1e-21 76.5 1.8 2.2e-21 75.6 1.8 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KIK47301.1 - 0.0085 16.3 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain SR-25 PF10500.9 KIK47301.1 - 0.024 14.3 18.3 0.035 13.7 18.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF5538 PF17692.1 KIK47303.1 - 0.0087 16.1 0.1 0.011 15.8 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5538) Pkinase PF00069.25 KIK47304.1 - 1.3e-64 218.1 0.0 1.6e-64 217.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK47304.1 - 1.9e-27 96.2 0.0 2.7e-27 95.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK47304.1 - 0.001 18.5 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIK47304.1 - 0.0052 15.8 0.0 0.0073 15.3 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KIK47304.1 - 0.019 14.6 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KIK47304.1 - 0.027 13.8 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIK47304.1 - 0.065 12.9 0.0 0.2 11.3 0.0 1.8 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 S_100 PF01023.19 KIK47304.1 - 0.065 12.9 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain APH PF01636.23 KIK47304.1 - 0.1 12.5 0.2 0.46 10.4 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1192 PF06698.11 KIK47305.1 - 0.11 12.6 0.6 0.51 10.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) ATP-cone PF03477.16 KIK47305.1 - 0.25 11.9 0.6 1.9 9.1 0.0 2.2 2 0 0 2 2 2 0 ATP cone domain FMN_dh PF01070.18 KIK47306.1 - 7.6e-107 357.3 0.0 1.2e-106 356.7 0.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KIK47306.1 - 7.7e-18 64.4 0.0 1.5e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 KIK47306.1 - 4.2e-06 26.0 0.3 4.3e-05 22.7 0.2 2.1 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KIK47306.1 - 6.3e-05 22.3 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KIK47306.1 - 8.5e-05 22.1 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KIK47306.1 - 0.016 14.5 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG LIM PF00412.22 KIK47307.1 - 3.8e-15 55.8 20.3 3.6e-07 30.3 2.3 5.7 5 1 0 5 5 5 4 LIM domain DUF3619 PF12279.8 KIK47308.1 - 0.04 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) DnaJ PF00226.31 KIK47309.1 - 8.1e-20 70.7 2.3 1.5e-19 69.8 2.3 1.5 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 KIK47309.1 - 0.042 14.2 2.0 0.069 13.4 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Sin_N PF04801.13 KIK47314.1 - 8.7e-23 81.2 0.0 1e-22 81.0 0.0 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region Gemini_AC4_5_2 PF08464.10 KIK47314.1 - 0.12 12.4 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region Otopetrin PF03189.13 KIK47315.1 - 0.19 10.5 0.0 0.19 10.5 0.0 2.0 2 0 0 2 2 2 0 Otopetrin AAA_18 PF13238.6 KIK47316.1 - 2.6e-30 105.6 0.1 6.4e-30 104.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIK47316.1 - 0.00056 20.2 0.0 0.0052 17.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KIK47316.1 - 0.00075 19.8 0.0 0.0023 18.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KIK47316.1 - 0.0011 19.4 0.0 0.0066 16.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain CPT PF07931.12 KIK47316.1 - 0.0015 18.4 0.0 0.003 17.4 0.0 1.6 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 KIK47316.1 - 0.0021 18.2 0.1 0.069 13.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 KIK47316.1 - 0.0026 18.2 0.0 0.006 17.0 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KIK47316.1 - 0.0026 17.7 0.2 0.17 11.7 0.0 2.4 2 0 0 2 2 2 1 NTPase dNK PF01712.19 KIK47316.1 - 0.0027 17.6 0.3 1.3 8.8 0.3 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase KTI12 PF08433.10 KIK47316.1 - 0.0033 16.9 0.2 0.012 15.1 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 ADK PF00406.22 KIK47316.1 - 0.004 17.3 0.1 0.21 11.7 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase SKI PF01202.22 KIK47316.1 - 0.018 15.2 0.1 0.04 14.0 0.1 1.6 1 1 0 1 1 1 0 Shikimate kinase ATP_bind_2 PF03668.15 KIK47316.1 - 0.022 14.1 0.1 0.17 11.2 0.1 2.1 1 1 0 1 1 1 0 P-loop ATPase protein family AAA_16 PF13191.6 KIK47316.1 - 0.041 14.3 0.1 0.057 13.8 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 KIK47316.1 - 0.045 13.0 0.1 0.097 11.9 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin Thymidylate_kin PF02223.17 KIK47316.1 - 0.059 13.0 0.1 7.8 6.1 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_25 PF13481.6 KIK47316.1 - 0.078 12.6 0.1 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KIK47316.1 - 0.087 12.2 0.6 0.59 9.4 0.0 2.0 2 0 0 2 2 2 0 KaiC RNA_helicase PF00910.22 KIK47316.1 - 0.12 12.8 0.1 0.34 11.3 0.0 1.8 2 0 0 2 2 2 0 RNA helicase Sigma54_activ_2 PF14532.6 KIK47316.1 - 0.13 12.4 0.0 0.38 10.9 0.0 1.8 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.14 KIK47316.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KIK47316.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KIK47316.1 - 0.18 11.5 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Cyclin_C_2 PF16899.5 KIK47318.1 - 1.5e-18 67.1 0.1 9.3e-16 58.1 0.0 2.6 2 1 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 KIK47318.1 - 3.2e-10 39.8 0.2 5.8e-10 39.0 0.0 1.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 KIK47318.1 - 0.0036 17.3 0.0 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Sde2_N_Ubi PF13019.6 KIK47318.1 - 5.1 6.9 6.8 1.5 8.6 2.8 2.1 2 1 1 3 3 3 0 Silencing defective 2 N-terminal ubiquitin domain DUF1764 PF08576.10 KIK47320.1 - 1.1e-10 42.3 14.9 1.8e-09 38.4 0.7 2.1 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF1764) Presenilin PF01080.17 KIK47320.1 - 2.3 6.9 4.8 2.5 6.8 4.8 1.0 1 0 0 1 1 1 0 Presenilin ARID PF01388.21 KIK47321.1 - 3.5e-15 56.4 0.0 1.3e-14 54.6 0.0 2.0 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 KIK47321.1 - 0.01 15.1 0.1 1.4 8.1 0.1 2.3 2 0 0 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa Arrestin_C PF02752.22 KIK47322.1 - 0.001 19.5 0.0 0.0024 18.3 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Ras PF00071.22 KIK47323.1 - 2.5e-55 186.5 0.0 3.5e-55 186.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK47323.1 - 1.5e-33 115.5 0.0 2.2e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK47323.1 - 2e-14 53.4 0.0 8.5e-14 51.4 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIK47323.1 - 4.8e-06 26.1 0.0 6.2e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KIK47323.1 - 1.9e-05 24.3 0.0 2.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIK47323.1 - 8e-05 22.7 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KIK47323.1 - 0.00022 21.7 0.3 0.00052 20.4 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIK47323.1 - 0.077 12.9 0.1 7.9 6.4 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase MRI PF15325.6 KIK47323.1 - 0.12 13.5 1.7 0.21 12.7 1.7 1.4 1 0 0 1 1 1 0 Modulator of retrovirus infection AMP-binding PF00501.28 KIK47326.1 - 1.6e-74 251.0 0.2 1.3e-73 248.0 0.2 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIK47326.1 - 3.7e-18 66.3 0.0 1.3e-17 64.5 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GYF PF02213.16 KIK47327.1 - 3.3e-15 55.5 0.1 6.6e-15 54.5 0.1 1.5 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KIK47327.1 - 0.056 13.3 0.1 0.15 11.9 0.1 1.8 1 0 0 1 1 1 0 GYF domain 2 FAD-oxidase_C PF02913.19 KIK47328.1 - 9.4e-53 179.4 0.0 1.2e-52 179.1 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KIK47328.1 - 6.7e-35 119.8 0.5 1.1e-34 119.1 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Lact-deh-memb PF09330.11 KIK47328.1 - 5.7e-05 22.6 0.0 0.0012 18.3 0.1 2.1 2 0 0 2 2 2 1 D-lactate dehydrogenase, membrane binding DUF3290 PF11694.8 KIK47329.1 - 0.21 11.6 4.0 1.8 8.5 0.3 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3290) FAD-oxidase_C PF02913.19 KIK47330.1 - 2e-57 194.7 0.0 3e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KIK47330.1 - 4.3e-29 101.0 0.0 7.9e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Vta1_C PF18097.1 KIK47330.1 - 0.22 11.2 0.1 1.6 8.5 0.1 2.2 2 0 0 2 2 2 0 Vta1 C-terminal domain MMM1 PF10296.9 KIK47332.1 - 1.8e-35 122.6 0.4 4.1e-18 65.5 0.0 3.0 1 1 2 3 3 3 3 Maintenance of mitochondrial morphology protein 1 TTL PF03133.15 KIK47333.1 - 8.7e-43 146.5 0.0 1.2e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family Cytochrom_B562 PF07361.11 KIK47334.1 - 0.0096 16.6 1.8 0.023 15.3 1.8 1.6 1 0 0 1 1 1 1 Cytochrome b562 HAP1_N PF04849.13 KIK47334.1 - 0.013 14.8 10.9 0.02 14.1 10.9 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Filament PF00038.21 KIK47334.1 - 0.022 14.4 10.6 0.038 13.6 8.4 2.0 1 1 1 2 2 2 0 Intermediate filament protein bZIP_1 PF00170.21 KIK47334.1 - 0.03 14.4 0.8 0.03 14.4 0.8 2.4 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.15 KIK47334.1 - 0.092 12.5 0.2 0.092 12.5 0.2 2.9 3 1 0 3 3 3 0 Septum formation initiator TSNAXIP1_N PF15739.5 KIK47334.1 - 0.13 12.7 9.1 0.82 10.1 5.1 2.9 3 0 0 3 3 3 0 Translin-associated factor X-interacting N-terminus DUF4407 PF14362.6 KIK47334.1 - 0.27 10.5 6.3 0.46 9.8 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAS PF13851.6 KIK47334.1 - 0.5 9.7 13.2 5.5 6.3 7.8 2.4 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 KIK47334.1 - 0.77 10.0 18.8 0.87 9.8 6.8 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 KIK47334.1 - 2.3 8.6 12.3 6.4 7.2 12.3 1.8 1 1 0 1 1 1 0 Fez1 Mto2_bdg PF12808.7 KIK47334.1 - 2.8 8.3 7.6 0.46 10.8 0.8 2.9 2 1 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Fungal_TACC PF12709.7 KIK47334.1 - 3.5 8.1 7.4 11 6.5 0.2 3.2 2 1 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins ZapB PF06005.12 KIK47334.1 - 4.3 7.8 18.2 0.45 11.0 1.7 2.8 2 1 1 3 3 2 0 Cell division protein ZapB YabA PF06156.13 KIK47334.1 - 8.6 7.1 7.9 1.1e+03 0.3 7.9 2.9 1 1 0 1 1 1 0 Initiation control protein YabA Pkinase PF00069.25 KIK47335.1 - 8.5e-68 228.6 0.0 1e-67 228.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK47335.1 - 1.6e-26 93.2 0.0 2.4e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK47335.1 - 6.7e-07 28.9 0.2 0.00024 20.6 0.1 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 KIK47335.1 - 0.0013 18.4 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KIK47335.1 - 0.14 11.0 0.1 0.28 10.1 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain BRCT_2 PF16589.5 KIK47336.1 - 9.8e-13 48.3 0.0 1.2e-05 25.6 0.0 2.5 1 1 1 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 KIK47336.1 - 1.2e-09 38.2 0.8 4.2e-09 36.5 0.8 2.0 1 0 0 1 1 1 1 Rap1 Myb domain Plk4_PB1 PF18190.1 KIK47336.1 - 0.14 12.4 0.0 27 5.0 0.0 2.6 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 1 Rap1-DNA-bind PF09197.10 KIK47336.1 - 0.71 10.5 4.0 1.3 9.6 2.3 2.4 2 1 0 2 2 2 0 Rap1, DNA-binding Sec7 PF01369.20 KIK47338.1 - 1.5e-30 106.3 0.0 2.5e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KIK47338.1 - 7.1e-15 55.4 0.1 1.5e-14 54.4 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KIK47338.1 - 2.6e-09 37.6 0.2 6.1e-09 36.3 0.2 1.6 1 0 0 1 1 1 1 PH domain RNR_inhib PF08591.10 KIK47338.1 - 0.019 16.2 0.2 0.15 13.4 0.2 2.6 1 0 0 1 1 1 0 Ribonucleotide reductase inhibitor PAS_11 PF14598.6 KIK47338.1 - 0.15 12.2 0.1 0.38 10.9 0.1 1.7 1 0 0 1 1 1 0 PAS domain Pescadillo_N PF06732.11 KIK47339.1 - 4.5e-122 406.8 0.9 8.6e-122 405.9 0.0 1.8 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 KIK47339.1 - 1.8e-10 41.1 0.0 4e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KIK47339.1 - 0.0013 19.1 0.0 0.0027 18.0 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KIK47339.1 - 0.0018 18.5 0.0 0.0053 17.0 0.0 1.8 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain CAMSAP_CC1 PF17095.5 KIK47339.1 - 2.2 8.2 12.2 0.44 10.4 7.1 2.3 1 1 1 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin LSM PF01423.22 KIK47340.1 - 1.9e-17 62.7 0.2 2.6e-17 62.2 0.2 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KIK47340.1 - 0.015 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Hfq protein Complex1_LYR PF05347.15 KIK47341.1 - 1.8e-12 47.1 0.2 2.1e-12 46.9 0.2 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Cyclin_N PF00134.23 KIK47344.1 - 8.8e-38 128.9 0.4 1.9e-37 127.8 0.4 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KIK47344.1 - 8.3e-09 35.6 0.1 2.1e-08 34.2 0.1 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain ATG101 PF07855.12 KIK47344.1 - 0.018 15.0 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Autophagy-related protein 101 DUF4224 PF13986.6 KIK47344.1 - 0.3 11.0 2.6 0.22 11.4 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) GFO_IDH_MocA PF01408.22 KIK47346.1 - 1.3e-11 45.3 0.0 2.8e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIK47346.1 - 0.02 14.9 0.0 0.048 13.7 0.0 1.8 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding_2 PF13380.6 KIK47346.1 - 0.1 13.1 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain F-box PF00646.33 KIK47347.1 - 0.13 12.2 0.3 0.33 10.9 0.3 1.7 1 0 0 1 1 1 0 F-box domain WAC_Acf1_DNA_bd PF10537.9 KIK47351.1 - 5.3e-36 123.2 1.5 5.3e-36 123.2 1.5 2.1 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KIK47351.1 - 2.1e-31 108.3 0.0 2.1e-31 108.3 0.0 3.8 4 1 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KIK47351.1 - 1e-11 44.9 0.6 3.1e-11 43.4 0.1 2.0 2 0 0 2 2 2 1 DDT domain WHIM1 PF15612.6 KIK47351.1 - 3.8e-05 23.1 0.0 8.9e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DDHD PF02862.17 KIK47351.1 - 0.0051 17.0 8.4 0.05 13.8 0.1 2.5 2 0 0 2 2 2 1 DDHD domain CENP-H PF05837.12 KIK47351.1 - 0.017 15.5 0.7 0.017 15.5 0.7 3.7 2 1 1 3 3 3 0 Centromere protein H (CENP-H) DUF3287 PF11690.8 KIK47351.1 - 0.22 11.2 3.7 1.2 8.8 2.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Nop53 PF07767.11 KIK47351.1 - 0.24 10.7 44.0 1.3 8.3 17.5 2.3 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Aa_trans PF01490.18 KIK47352.1 - 2.8e-59 200.9 22.8 3.4e-59 200.6 22.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KIK47352.1 - 1.1e-07 31.2 10.1 1.1e-07 31.2 10.1 2.2 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family CSN8_PSD8_EIF3K PF10075.9 KIK47353.1 - 1e-21 77.4 0.0 1.6e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family WD40 PF00400.32 KIK47354.1 - 7.7e-59 194.3 11.5 1.7e-09 38.1 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK47354.1 - 1.3e-26 92.7 0.2 3.2e-05 24.1 0.0 5.8 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK47354.1 - 1.6e-11 44.4 0.0 1.5e-06 28.2 0.0 3.7 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK47354.1 - 1.8e-08 33.7 3.0 0.004 16.2 0.0 4.0 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK47354.1 - 6.7e-07 28.3 4.9 0.11 11.1 0.2 4.9 1 1 4 5 5 5 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK47354.1 - 1.2e-06 28.1 0.0 5e-05 22.8 0.0 3.0 2 1 0 3 3 3 1 WD40-like domain Coatomer_WDAD PF04053.14 KIK47354.1 - 0.0019 17.4 0.1 0.022 13.8 0.0 2.3 1 1 2 3 3 3 1 Coatomer WD associated region Kelch_6 PF13964.6 KIK47354.1 - 0.013 15.8 0.1 0.65 10.4 0.0 3.4 3 0 0 3 3 3 0 Kelch motif DUF1513 PF07433.11 KIK47354.1 - 0.062 12.4 0.1 2.1 7.4 0.0 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1513) IKI3 PF04762.12 KIK47354.1 - 0.085 10.8 0.2 0.39 8.7 0.1 2.0 2 1 0 2 2 2 0 IKI3 family Frtz PF11768.8 KIK47354.1 - 0.097 11.0 0.0 0.62 8.3 0.0 1.9 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 KIK47354.1 - 0.17 10.8 1.1 7.2 5.4 0.0 3.3 1 1 3 4 4 4 0 Partner and localizer of BRCA2 WD40 domain PD40 PF07676.12 KIK47354.1 - 0.19 11.7 0.3 18 5.4 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat ubiquitin PF00240.23 KIK47355.1 - 4.5e-137 446.0 18.7 1.3e-33 114.6 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 KIK47355.1 - 2.8e-63 209.7 20.7 3e-15 55.8 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KIK47355.1 - 3.5e-23 81.8 9.2 0.00045 20.6 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 KIK47355.1 - 4e-16 58.7 3.0 0.033 14.1 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIK47355.1 - 1.6e-14 54.0 2.7 0.11 12.6 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KIK47355.1 - 2.2e-14 53.6 8.0 0.044 14.1 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain DUF2407 PF10302.9 KIK47355.1 - 5e-13 49.5 1.1 0.36 11.4 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KIK47355.1 - 6.3e-10 39.1 0.4 1.1 9.1 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 KIK47355.1 - 4.3e-07 29.9 24.6 16 5.7 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 KIK47355.1 - 5.2e-07 29.2 0.6 1 8.7 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 KIK47355.1 - 3.9e-06 26.9 2.8 12 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Big_7 PF17957.1 KIK47355.1 - 4.4e-06 27.4 0.1 30 5.5 0.0 4.2 4 0 0 4 4 4 0 Bacterial Ig domain DUF2870 PF11069.8 KIK47355.1 - 5.7e-06 26.6 0.0 30 5.1 0.0 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 KIK47355.1 - 1e-05 25.3 3.8 11 5.9 0.0 4.3 4 0 0 4 4 4 0 ACT domain TmoB PF06234.12 KIK47355.1 - 1.1e-05 25.4 0.1 29 4.9 0.0 4.8 4 0 0 4 4 4 0 Toluene-4-monooxygenase system protein B (TmoB) UDP-g_GGTase PF06427.11 KIK47355.1 - 5.6e-05 23.2 3.2 6.9 6.8 0.0 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 KIK47355.1 - 0.00033 20.1 0.0 21 4.4 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 KIK47355.1 - 0.00036 21.1 0.9 73 4.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain DUF493 PF04359.14 KIK47355.1 - 0.003 18.1 0.1 1.4e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 KIK47355.1 - 0.007 16.5 0.0 91 3.3 0.0 4.2 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 KIK47355.1 - 0.011 15.9 5.3 64 3.8 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 KIK47355.1 - 0.041 13.7 9.2 43 4.1 0.1 4.4 4 0 0 4 4 4 0 FlgD Ig-like domain Tash_PEST PF07708.11 KIK47355.1 - 0.14 12.3 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif Phage_sheath_1N PF17481.2 KIK47355.1 - 0.35 11.4 8.8 51 4.4 1.5 4.0 1 1 2 3 3 3 0 Phage tail sheath protein beta-sandwich domain YcgR_2 PF12945.7 KIK47355.1 - 1.1 9.5 4.6 2.4e+02 2.0 0.0 4.0 4 0 0 4 4 4 0 Flagellar protein YcgR PI3K_p85B PF02192.16 KIK47355.1 - 1.2 9.0 8.5 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Cnl2_NKP2 PF09447.10 KIK47355.1 - 1.2 9.3 9.9 1e+02 3.2 0.1 4.4 4 0 0 4 4 4 0 Cnl2/NKP2 family protein Fcf1 PF04900.12 KIK47356.1 - 1.9e-24 85.9 0.1 3.4e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 Fcf1 DUF2012 PF09430.10 KIK47357.1 - 7.7e-22 77.7 0.0 1.7e-21 76.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 KIK47357.1 - 7e-05 23.0 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain fn3_3 PF14686.6 KIK47357.1 - 0.00078 19.2 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarbopepD_reg_2 PF13715.6 KIK47357.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 CarboxypepD_reg-like domain SOP4 PF17081.5 KIK47357.1 - 0.019 14.5 0.0 0.046 13.2 0.0 1.6 2 0 0 2 2 2 0 Suppressor of PMA 1-7 protein PepSY_TM PF03929.16 KIK47357.1 - 0.037 13.7 0.0 0.05 13.3 0.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Branch_AA_trans PF05525.13 KIK47359.1 - 0.014 14.3 0.5 0.018 13.9 0.5 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport protein 7tm_7 PF08395.12 KIK47359.1 - 0.044 13.0 1.2 0.062 12.5 1.2 1.2 1 0 0 1 1 1 0 7tm Chemosensory receptor CopD PF05425.13 KIK47359.1 - 0.052 14.0 0.5 0.098 13.1 0.5 1.4 1 0 0 1 1 1 0 Copper resistance protein D 7TM_GPCR_Srd PF10317.9 KIK47359.1 - 0.076 12.2 1.8 0.11 11.7 1.8 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd Phage_holin_3_6 PF07332.11 KIK47359.1 - 0.12 12.4 0.9 0.2 11.7 0.9 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III GST_N_3 PF13417.6 KIK47360.1 - 1.4e-08 35.1 0.0 2.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIK47360.1 - 1.5e-05 25.3 0.0 3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK47360.1 - 3.6e-05 23.7 0.0 0.00018 21.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KIK47360.1 - 0.00019 21.7 0.0 0.00054 20.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain FAD_binding_6 PF00970.24 KIK47361.1 - 9.4e-34 115.7 0.0 1.5e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KIK47361.1 - 2.8e-33 114.8 0.0 4.3e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KIK47361.1 - 3.2e-06 27.4 0.0 0.00086 19.4 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KIK47361.1 - 0.0061 16.8 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DSPc PF00782.20 KIK47362.1 - 1.8e-21 76.4 0.0 4.9e-19 68.5 0.0 3.1 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIK47362.1 - 0.015 14.9 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KIK47362.1 - 0.046 13.8 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 KIK47362.1 - 0.13 12.6 0.0 0.42 10.9 0.0 1.8 2 0 0 2 2 2 0 Rit1 DUSP-like domain DUF846 PF05832.12 KIK47363.1 - 4.5e-52 175.8 8.4 5.9e-52 175.4 8.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Myelin_PLP PF01275.19 KIK47363.1 - 0.013 15.4 2.9 0.019 14.9 2.9 1.2 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) YbhQ PF11076.8 KIK47363.1 - 2.4 8.2 7.2 0.09 12.8 1.1 1.6 2 0 0 2 2 2 0 Putative inner membrane protein YbhQ LRR_4 PF12799.7 KIK47365.1 - 7.9e-11 42.0 12.3 0.024 15.1 0.0 8.6 7 2 2 9 9 9 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIK47365.1 - 4e-05 23.3 9.9 1.2 8.9 0.0 6.8 7 1 0 7 7 7 2 Leucine rich repeat LRR_6 PF13516.6 KIK47365.1 - 0.056 13.5 22.2 14 6.0 0.1 8.6 11 0 0 11 11 11 0 Leucine Rich repeat LRR_1 PF00560.33 KIK47365.1 - 0.24 12.1 3.9 62 4.7 0.0 5.7 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_2 PF07723.13 KIK47365.1 - 0.41 11.4 3.9 74 4.3 0.0 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat Pkinase_Tyr PF07714.17 KIK47367.1 - 9.1e-05 21.9 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK47367.1 - 0.00025 20.5 0.0 0.00041 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIK47367.1 - 0.0015 18.5 0.4 0.0038 17.2 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KIK47367.1 - 0.028 13.8 0.0 0.07 12.5 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIK47367.1 - 0.033 13.1 0.0 0.033 13.1 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain AA_permease PF00324.21 KIK47369.1 - 1e-122 410.2 42.6 1.2e-122 409.9 42.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK47369.1 - 9.3e-36 123.6 45.6 1.2e-35 123.3 45.6 1.0 1 0 0 1 1 1 1 Amino acid permease RhoGEF PF00621.20 KIK47370.1 - 8.5e-39 133.7 0.0 1.3e-38 133.1 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain LRR_8 PF13855.6 KIK47370.1 - 4.3e-09 36.0 3.8 6.5e-05 22.6 0.3 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KIK47370.1 - 1.6e-08 34.7 1.4 0.0079 16.6 0.3 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KIK47370.1 - 0.024 15.1 4.2 4.9 8.1 0.5 4.1 3 1 0 3 3 3 0 Leucine Rich Repeat WD40 PF00400.32 KIK47371.1 - 0.0014 19.4 0.3 0.0038 18.0 0.3 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat Methyltransf_16 PF10294.9 KIK47371.1 - 0.089 12.5 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Dak1 PF02733.17 KIK47372.1 - 3.7e-106 354.5 0.3 6.4e-106 353.7 0.1 1.5 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.17 KIK47372.1 - 6.6e-39 133.6 4.8 1e-38 132.9 4.8 1.3 1 0 0 1 1 1 1 DAK2 domain ACT_7 PF13840.6 KIK47372.1 - 0.23 11.3 0.7 14 5.5 0.0 3.3 3 0 0 3 3 3 0 ACT domain UCH PF00443.29 KIK47376.1 - 1.6e-71 240.8 0.0 2e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KIK47376.1 - 6.9e-14 52.2 0.1 2e-13 50.7 0.1 1.9 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 KIK47376.1 - 3.1e-13 50.0 0.0 3.3e-05 23.6 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 KIK47376.1 - 0.0064 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal DUF1712 PF08217.11 KIK47377.1 - 3.1e-23 82.1 0.0 4.2e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) TFIID_30kDa PF03540.13 KIK47380.1 - 6.3e-26 90.1 0.0 9.6e-26 89.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 KIK47380.1 - 0.015 15.3 0.0 0.33 11.0 0.0 2.2 2 0 0 2 2 2 0 Bromodomain associated CytochromB561_N PF09786.9 KIK47380.1 - 0.087 11.8 0.2 0.11 11.5 0.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF3464 PF11947.8 KIK47380.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Ribosomal_60s PF00428.19 KIK47380.1 - 0.14 12.8 2.9 4.7 7.9 0.0 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Fungal_trans PF04082.18 KIK47381.1 - 7.1e-10 38.4 0.1 2.1e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain RNA_pol_Rpc4 PF05132.14 KIK47382.1 - 6.9e-33 114.2 0.1 6.9e-33 114.2 0.1 2.6 3 0 0 3 3 3 1 RNA polymerase III RPC4 TRAM PF01938.20 KIK47382.1 - 0.15 12.1 0.8 1.2 9.2 0.2 2.3 2 0 0 2 2 2 0 TRAM domain Pribosyltran PF00156.27 KIK47383.1 - 8.2e-07 28.7 0.0 1.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Mito_carr PF00153.27 KIK47384.1 - 5.3e-66 218.6 3.1 9.9e-22 76.7 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein KduI PF04962.12 KIK47384.1 - 0.081 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 KduI/IolB family FAD_binding_3 PF01494.19 KIK47386.1 - 1.2e-18 67.5 0.0 3e-18 66.2 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIK47386.1 - 1.4e-09 38.0 1.2 3.4e-05 23.6 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIK47386.1 - 4.1e-09 36.1 0.1 0.00015 21.1 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK47386.1 - 1.2e-07 31.8 0.1 3.2e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIK47386.1 - 2.9e-07 29.9 0.5 1.6e-06 27.5 0.5 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK47386.1 - 6.2e-06 25.6 0.1 1e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KIK47386.1 - 9.9e-06 24.5 0.1 0.00013 20.8 0.1 2.1 1 1 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 KIK47386.1 - 4.9e-05 22.8 0.1 0.26 10.5 0.0 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KIK47386.1 - 0.0064 16.5 0.2 0.42 10.6 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KIK47386.1 - 0.0087 15.3 0.1 0.017 14.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIK47386.1 - 0.017 14.0 0.0 2.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 KIK47386.1 - 0.022 13.9 0.2 0.04 13.0 0.1 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 KIK47386.1 - 0.038 13.2 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 KIK47386.1 - 0.12 11.6 0.1 0.25 10.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GMC_oxred_N PF00732.19 KIK47386.1 - 0.15 11.4 0.0 0.63 9.4 0.0 1.9 2 0 0 2 2 2 0 GMC oxidoreductase FAD_oxidored PF12831.7 KIK47386.1 - 0.16 11.3 0.1 0.27 10.5 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase ParA PF10609.9 KIK47388.1 - 2.9e-96 321.7 0.0 3.4e-96 321.4 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KIK47388.1 - 2.2e-10 40.7 0.0 5.5e-10 39.4 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KIK47388.1 - 1.2e-06 27.9 1.3 0.00076 18.7 0.2 2.9 1 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.18 KIK47388.1 - 0.00033 20.2 0.0 0.69 9.3 0.0 2.5 2 1 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.6 KIK47388.1 - 0.00044 20.2 0.2 0.0067 16.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 KIK47388.1 - 0.00063 19.3 0.0 0.002 17.7 0.0 1.7 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 KIK47388.1 - 0.0025 17.7 0.0 0.009 15.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIK47388.1 - 0.005 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KIK47388.1 - 0.014 15.3 0.1 0.035 14.0 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase VirE PF05272.11 KIK47388.1 - 0.13 12.0 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Virulence-associated protein E NB-ARC PF00931.22 KIK47388.1 - 0.13 11.4 0.1 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain Pkinase PF00069.25 KIK47389.1 - 0.0012 18.3 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KIK47390.1 - 1.4e-40 139.4 0.0 1.7e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK47390.1 - 1.5e-24 86.7 0.0 2.1e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK47390.1 - 0.0028 17.6 0.4 0.026 14.4 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIK47390.1 - 0.0031 16.5 0.0 0.0046 15.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KIK47390.1 - 0.0064 15.9 0.2 0.012 15.0 0.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIK47390.1 - 0.0074 15.9 0.1 0.17 11.4 0.0 2.1 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KIK47390.1 - 0.17 11.5 0.1 0.35 10.5 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Symplekin_C PF12295.8 KIK47391.1 - 5.5e-63 212.4 0.9 5.5e-63 212.4 0.9 2.2 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 KIK47391.1 - 1.8e-49 168.4 0.9 4.2e-49 167.2 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) HEAT_2 PF13646.6 KIK47391.1 - 0.08 13.3 2.7 0.34 11.3 0.1 3.5 4 1 0 4 4 4 0 HEAT repeats HEAT PF02985.22 KIK47391.1 - 0.11 12.8 0.3 3.4 8.2 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat V-ATPase_G PF03179.15 KIK47392.1 - 1.1e-34 119.1 11.9 1.3e-34 118.9 11.9 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Csa1 PF06023.12 KIK47392.1 - 0.12 11.8 0.6 0.13 11.6 0.6 1.0 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 Lipoprotein_3 PF00938.17 KIK47392.1 - 0.17 12.1 1.1 0.32 11.2 0.2 1.8 2 1 0 2 2 2 0 Lipoprotein ATP-synt_B PF00430.18 KIK47392.1 - 6.2 6.9 15.2 14 5.8 15.2 1.7 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Fungal_trans PF04082.18 KIK47393.1 - 5.6e-17 61.7 0.1 7.9e-17 61.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK47393.1 - 1.2e-09 38.2 11.1 2.3e-09 37.2 11.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prot_inhib_II PF02428.15 KIK47393.1 - 3.2 8.3 10.8 4.6 7.8 0.5 3.0 2 1 1 3 3 3 0 Potato type II proteinase inhibitor family Ribosomal_60s PF00428.19 KIK47394.1 - 5.6e-28 97.4 9.7 6.5e-28 97.2 9.7 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 KIK47394.1 - 0.023 15.0 0.6 0.033 14.5 0.0 1.5 2 0 0 2 2 2 0 EF-hand domain DUF3824 PF12868.7 KIK47394.1 - 0.027 15.2 2.1 0.036 14.7 2.1 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Cytomega_UL84 PF06284.11 KIK47394.1 - 0.064 11.7 1.4 0.07 11.6 1.4 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein UBA_6 PF18039.1 KIK47394.1 - 0.13 12.2 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain Ribosomal_S19 PF00203.21 KIK47395.1 - 3.1e-31 107.1 0.2 5e-31 106.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 KIK47395.1 - 0.031 14.3 0.0 0.038 14.1 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH RhoGAP PF00620.27 KIK47396.1 - 9.8e-34 116.4 0.3 1.9e-33 115.5 0.3 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KIK47396.1 - 2.5e-25 88.5 40.8 2e-10 40.8 6.8 4.9 5 0 0 5 5 5 4 LIM domain F-box-like PF12937.7 KIK47398.1 - 3.8e-09 36.3 3.0 1.8e-08 34.1 3.0 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIK47398.1 - 0.044 13.7 9.6 0.031 14.2 2.7 3.7 3 1 0 3 3 3 0 F-box domain ABC_membrane PF00664.23 KIK47399.1 - 5e-66 223.2 37.2 4.9e-35 121.5 15.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK47399.1 - 3.6e-51 173.3 0.0 6.4e-30 104.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIK47399.1 - 2.4e-08 33.7 0.0 0.0021 17.5 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KIK47399.1 - 8.9e-05 22.6 1.3 0.2 11.7 0.2 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KIK47399.1 - 0.00057 19.8 0.2 2.3 8.0 0.0 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIK47399.1 - 0.00064 20.1 0.0 0.43 10.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIK47399.1 - 0.00091 19.2 1.8 0.66 9.9 0.2 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KIK47399.1 - 0.0046 16.7 1.1 0.59 9.9 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KIK47399.1 - 0.008 15.9 0.2 1.5 8.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 KIK47399.1 - 0.019 15.2 0.8 4.1 7.6 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 KIK47399.1 - 0.036 14.6 4.0 1.5 9.2 0.1 2.8 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.25 KIK47399.1 - 0.038 13.6 0.0 2.6 7.6 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.6 KIK47399.1 - 0.056 13.7 0.8 11 6.2 0.1 3.3 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 KIK47399.1 - 0.06 13.3 1.0 1.4 9.0 0.1 2.9 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KIK47399.1 - 0.062 12.5 1.3 5.9 6.0 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 KIK47399.1 - 0.068 12.7 0.5 14 5.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 KIK47399.1 - 0.079 12.9 2.0 0.19 11.6 0.2 2.2 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 KIK47399.1 - 0.11 12.0 0.2 3.2 7.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KIK47399.1 - 0.15 12.1 3.0 6.4 6.8 0.3 2.6 2 0 0 2 2 2 0 Dynamin family AAA_15 PF13175.6 KIK47399.1 - 0.21 11.3 0.1 6.1 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 KIK47399.1 - 0.21 10.5 1.7 0.46 9.3 0.2 1.9 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 KIK47399.1 - 0.35 10.1 1.9 15 4.8 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 KIK47399.1 - 0.83 9.7 2.5 2 8.5 0.5 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain Gpi1 PF05024.15 KIK47399.1 - 5.7 7.0 12.9 0.11 12.5 4.3 2.4 2 1 1 3 3 3 0 N-acetylglucosaminyl transferase component (Gpi1) DEAD PF00270.29 KIK47400.1 - 4.6e-39 134.0 0.0 1e-38 132.8 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK47400.1 - 6.6e-22 78.0 0.2 8e-21 74.5 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK47400.1 - 3e-07 30.6 0.0 6.8e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KIK47400.1 - 0.009 16.4 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK47400.1 - 0.061 13.6 0.1 2.7 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 KIK47400.1 - 0.14 10.9 0.0 0.27 10.0 0.0 1.4 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Presenilin PF01080.17 KIK47400.1 - 2.4 6.8 5.4 3.5 6.3 5.4 1.1 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 KIK47400.1 - 2.4 6.8 7.8 4.3 6.0 7.8 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MOZ_SAS PF01853.18 KIK47402.1 - 8.3e-73 243.9 0.0 1.2e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KIK47402.1 - 5.7e-19 67.5 1.4 1.3e-18 66.3 0.2 2.2 2 0 0 2 2 2 1 MYST family zinc finger domain PHD PF00628.29 KIK47402.1 - 1.9e-10 40.5 6.8 1.9e-10 40.5 6.8 3.2 2 1 1 3 3 3 1 PHD-finger zf-RING_2 PF13639.6 KIK47402.1 - 3.3 8.1 14.2 0.38 11.1 9.3 2.1 2 0 0 2 2 2 0 Ring finger domain C1_2 PF03107.16 KIK47402.1 - 5.4 7.4 11.1 2.9 8.3 8.2 2.1 2 0 0 2 2 2 0 C1 domain Pkinase PF00069.25 KIK47405.1 - 4.2e-48 164.0 0.0 1.6e-47 162.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK47405.1 - 8.4e-18 64.6 0.0 1.8e-17 63.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase DUF4813 PF16072.5 KIK47405.1 - 0.15 11.7 8.7 0.23 11.1 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) TMEM252 PF15664.5 KIK47405.1 - 0.18 11.5 1.5 0.36 10.5 1.5 1.4 1 0 0 1 1 1 0 Transmembrane protein 252 family TRAP_alpha PF03896.16 KIK47407.1 - 3e-06 26.7 0.0 3.8e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit ABA_WDS PF02496.16 KIK47407.1 - 0.00017 22.0 0.1 0.00029 21.2 0.1 1.3 1 0 0 1 1 1 1 ABA/WDS induced protein MFS_1 PF07690.16 KIK47411.1 - 3.3e-39 134.8 25.7 3.3e-39 134.8 25.7 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK47411.1 - 2.4e-17 62.9 2.1 2.4e-17 62.9 2.1 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter BNIP3 PF06553.12 KIK47411.1 - 0.22 11.2 0.2 0.41 10.3 0.0 1.5 2 0 0 2 2 2 0 BNIP3 WD40 PF00400.32 KIK47413.1 - 2.9e-31 107.0 13.7 9.7e-09 35.7 0.1 8.0 8 0 0 8 8 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK47413.1 - 7.3e-11 42.2 0.1 0.13 12.6 0.0 5.6 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 KIK47413.1 - 1.4e-10 41.7 3.5 7.1e-10 39.4 0.2 2.4 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) TPR_2 PF07719.17 KIK47413.1 - 4.2e-10 38.9 3.7 0.21 11.8 0.2 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIK47413.1 - 5.8e-09 35.4 2.0 0.21 11.5 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat eIF2A PF08662.11 KIK47413.1 - 0.00031 20.7 0.0 0.59 10.0 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A BTAD PF03704.17 KIK47413.1 - 0.00066 20.1 1.6 1.8 9.0 0.1 3.7 3 2 0 3 3 3 2 Bacterial transcriptional activator domain Ge1_WD40 PF16529.5 KIK47413.1 - 0.00093 18.2 0.0 0.012 14.6 0.0 2.7 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_7 PF13176.6 KIK47413.1 - 0.0011 18.8 0.5 33 4.8 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Nup160 PF11715.8 KIK47413.1 - 0.0026 16.5 0.1 0.14 10.8 0.0 2.3 2 0 0 2 2 2 1 Nucleoporin Nup120/160 DUF3856 PF12968.7 KIK47413.1 - 0.014 15.5 0.3 0.16 12.1 0.0 2.7 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_11 PF13414.6 KIK47413.1 - 0.31 10.8 5.3 3.9 7.3 0.6 3.5 4 0 0 4 4 4 0 TPR repeat TPR_12 PF13424.6 KIK47413.1 - 0.42 10.9 6.7 20 5.6 1.9 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK47413.1 - 0.44 11.2 2.5 41 4.9 0.4 4.4 6 0 0 6 6 4 0 Tetratricopeptide repeat BUD22 PF09073.10 KIK47414.1 - 4.5 6.5 32.3 5.6 6.2 32.3 1.2 1 0 0 1 1 1 0 BUD22 IIGP PF05049.13 KIK47416.1 - 3.1e-23 82.5 0.0 9e-23 80.9 0.0 1.6 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KIK47416.1 - 2e-07 31.1 0.0 4.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK47416.1 - 0.00095 19.1 0.1 0.0024 17.8 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KIK47416.1 - 0.0039 17.6 5.6 0.072 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 KIK47416.1 - 0.0088 16.6 0.1 0.064 13.8 0.0 2.1 2 0 0 2 2 2 1 ABC transporter Dynamin_N PF00350.23 KIK47416.1 - 0.0097 16.0 0.7 0.15 12.1 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 KIK47416.1 - 0.011 16.0 0.1 0.06 13.6 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 KIK47416.1 - 0.043 13.6 0.1 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Roc PF08477.13 KIK47416.1 - 0.078 13.2 0.0 0.22 11.7 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF3987 PF13148.6 KIK47416.1 - 0.61 9.0 0.0 0.61 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF87 PF01935.17 KIK47416.1 - 2.6 8.1 7.6 0.25 11.4 0.6 2.4 2 1 1 3 3 3 0 Helicase HerA, central domain ERM PF00769.19 KIK47416.1 - 3.1 7.6 24.8 4.8 6.9 24.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family VIR_N PF15912.5 KIK47416.1 - 3.6 7.1 5.1 54 3.2 4.9 2.1 2 0 0 2 2 2 0 Virilizer, N-terminal Presenilin PF01080.17 KIK47416.1 - 5.1 5.8 5.8 7.9 5.1 5.8 1.2 1 0 0 1 1 1 0 Presenilin polyprenyl_synt PF00348.17 KIK47417.1 - 7.8e-62 208.6 0.0 1.8e-56 191.1 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase WD40 PF00400.32 KIK47419.1 - 1.4e-33 114.3 18.8 9.7e-07 29.4 0.2 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK47419.1 - 3.4e-11 43.3 2.2 0.00099 19.4 0.0 4.2 2 2 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 KIK47419.1 - 4.8e-11 43.2 4.4 2.1e-09 37.9 0.6 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) PD40 PF07676.12 KIK47419.1 - 2.4e-05 24.1 0.1 7.8 6.6 0.0 5.1 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK47419.1 - 0.003 16.6 0.7 11 4.8 0.0 4.3 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Asp PF00026.23 KIK47421.1 - 2.4e-65 221.0 7.8 2.9e-65 220.8 7.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK47421.1 - 1.1e-10 42.0 5.5 1.1e-09 38.8 3.0 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal WD40 PF00400.32 KIK47422.1 - 7e-17 61.5 2.6 3.3e-05 24.5 0.0 5.5 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK47422.1 - 5.6e-05 23.4 0.0 1.4 9.2 0.0 3.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KIK47422.1 - 0.0059 15.7 0.0 0.0086 15.2 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region RNA_pol_Rpb5_C PF01191.19 KIK47423.1 - 6e-32 109.3 0.5 1.1e-31 108.5 0.3 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KIK47423.1 - 1.8e-30 105.3 0.1 3.4e-30 104.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KIK47423.1 - 0.0011 19.0 0.0 0.0024 17.9 0.0 1.7 1 1 0 1 1 1 1 Restriction endonuclease 3-HAO PF06052.12 KIK47424.1 - 8.2e-58 194.3 0.0 9.2e-58 194.2 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KIK47424.1 - 3.6e-07 29.8 0.0 6.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KIK47424.1 - 0.002 18.0 0.0 0.01 15.8 0.0 1.8 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KIK47424.1 - 0.012 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Cupin Terpene_synth_C PF03936.16 KIK47425.1 - 9e-05 21.9 0.1 0.00014 21.3 0.1 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Minor_capsid_1 PF10665.9 KIK47429.1 - 0.051 13.8 0.0 0.051 13.8 0.0 1.1 1 0 0 1 1 1 0 Minor capsid protein Cys_Met_Meta_PP PF01053.20 KIK47433.1 - 2.1e-124 414.9 0.0 2.7e-124 414.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.26 KIK47433.1 - 3.4e-16 59.2 0.2 1.1e-15 57.6 0.2 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KIK47433.1 - 1.5e-05 25.2 0.0 5e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal Met_gamma_lyase PF06838.11 KIK47433.1 - 4.1e-05 22.3 0.0 0.00014 20.5 0.0 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 KIK47433.1 - 0.0015 17.9 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GalKase_gal_bdg PF10509.9 KIK47433.1 - 0.0026 17.3 0.0 0.0052 16.3 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Beta_elim_lyase PF01212.21 KIK47433.1 - 0.045 13.0 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase SelA PF03841.13 KIK47433.1 - 0.045 12.7 0.0 1.7 7.5 0.0 2.2 2 0 0 2 2 2 0 L-seryl-tRNA selenium transferase zf-HIT PF04438.16 KIK47434.1 - 4.6e-07 29.6 10.9 7.7e-07 28.9 10.9 1.4 1 0 0 1 1 1 1 HIT zinc finger SfsA PF03749.13 KIK47434.1 - 0.063 13.2 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Sugar fermentation stimulation protein RE domain HATPase_c PF02518.26 KIK47435.1 - 5e-19 68.9 0.0 1.1e-18 67.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KIK47435.1 - 1.4e-18 67.1 0.0 2.7e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KIK47435.1 - 5.3e-14 52.0 0.1 1.9e-13 50.2 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 KIK47435.1 - 6.2e-08 33.4 0.1 0.035 14.7 0.0 3.3 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.6 KIK47435.1 - 0.00022 21.5 0.0 0.33 11.3 0.0 3.4 3 0 0 3 3 3 2 GAF domain DUF1943 PF09172.11 KIK47435.1 - 0.086 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF2802 PF10975.8 KIK47435.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) LapA_dom PF06305.11 KIK47436.1 - 0.92 9.4 5.1 1.8 8.4 0.2 3.6 2 1 1 3 3 3 0 Lipopolysaccharide assembly protein A domain UDG PF03167.19 KIK47437.1 - 5.9e-18 65.3 0.0 3.2e-17 62.9 0.0 2.0 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily bZIP_1 PF00170.21 KIK47439.1 - 0.0018 18.3 3.1 0.0033 17.5 3.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIK47439.1 - 0.013 15.6 1.9 0.026 14.6 1.9 1.4 1 0 0 1 1 1 0 Basic region leucine zipper WD40_alt PF14077.6 KIK47439.1 - 0.26 11.2 0.2 0.46 10.4 0.2 1.3 1 0 0 1 1 1 0 Alternative WD40 repeat motif CCDC106 PF15794.5 KIK47439.1 - 0.77 9.4 4.2 0.19 11.4 0.2 1.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 ERCC3_RAD25_C PF16203.5 KIK47440.1 - 9.4e-124 411.5 0.1 1.9e-123 410.5 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KIK47440.1 - 1.4e-37 128.7 0.0 3.3e-37 127.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK47440.1 - 8.3e-17 61.7 0.0 1.8e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIK47440.1 - 1.7e-10 41.2 0.0 6e-10 39.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KIK47440.1 - 8e-10 37.9 0.1 1.1e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Cas_Csm6 PF09659.10 KIK47440.1 - 0.36 9.6 2.5 9.5 4.9 1.1 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csm6) Ribosomal_L5 PF00281.19 KIK47441.1 - 9.1e-21 74.0 0.1 1.9e-20 72.9 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 KIK47441.1 - 9.8e-21 73.8 0.0 1.6e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus HTH_ABP1_N PF18107.1 KIK47441.1 - 0.036 13.8 0.5 0.078 12.7 0.5 1.5 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain Methyltr_RsmB-F PF01189.17 KIK47442.1 - 3.4e-28 98.7 0.3 6.5e-28 97.7 0.0 1.7 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Fibrillarin PF01269.17 KIK47442.1 - 0.021 13.9 0.0 0.058 12.5 0.0 1.7 2 0 0 2 2 2 0 Fibrillarin Methyltransf_31 PF13847.6 KIK47442.1 - 0.15 11.8 0.0 0.42 10.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DnaJ_C PF01556.18 KIK47443.1 - 8e-38 129.8 0.1 1.1e-37 129.4 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIK47443.1 - 7.8e-25 86.8 1.4 1.6e-24 85.8 1.4 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KIK47443.1 - 8.9e-12 45.2 20.0 1.5e-11 44.5 20.0 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KIK47443.1 - 3.3e-05 23.8 9.7 0.0081 16.1 1.3 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein LTV PF04180.14 KIK47443.1 - 0.00052 19.9 2.2 0.0011 18.8 2.2 1.5 1 0 0 1 1 1 1 Low temperature viability protein HypA PF01155.19 KIK47443.1 - 1.5 8.9 14.4 3.6 7.6 5.7 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KIK47443.1 - 2.5 8.2 9.8 11 6.2 2.7 2.3 2 0 0 2 2 2 0 Double zinc ribbon ThuA PF06283.11 KIK47444.1 - 1.2e-60 205.3 0.0 1.4e-60 205.2 0.0 1.0 1 0 0 1 1 1 1 Trehalose utilisation DUF4159 PF13709.6 KIK47444.1 - 0.0038 16.6 0.0 0.0046 16.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4159) MFS_2 PF13347.6 KIK47445.1 - 0.0016 17.1 8.2 0.0016 17.1 8.2 1.8 2 0 0 2 2 2 1 MFS/sugar transport protein Metallophos_2 PF12850.7 KIK47448.1 - 0.015 15.5 0.0 0.019 15.2 0.0 1.1 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Pyr_redox_2 PF07992.14 KIK47450.1 - 1.2e-54 185.6 0.5 1.5e-54 185.3 0.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KIK47450.1 - 1.7e-18 66.3 0.4 3.8e-18 65.2 0.4 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KIK47450.1 - 1.5e-12 47.9 4.6 7e-12 45.8 0.2 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK47450.1 - 2.9e-09 36.6 0.2 1.3e-08 34.5 0.1 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 KIK47450.1 - 4.2e-08 33.6 0.0 1.3e-07 32.0 0.0 1.9 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.6 KIK47450.1 - 2.7e-07 30.4 0.1 1.6e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain K_oxygenase PF13434.6 KIK47450.1 - 2.2e-05 23.8 0.1 0.19 10.9 0.0 2.9 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 KIK47450.1 - 0.0042 17.5 0.3 0.23 11.9 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.14 KIK47450.1 - 0.016 13.9 0.0 7.6 5.1 0.0 3.1 3 0 0 3 3 3 0 HI0933-like protein DUF5436 PF17504.2 KIK47451.1 - 0.076 13.3 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5436) Serinc PF03348.15 KIK47452.1 - 3.3e-162 540.3 13.7 3.7e-162 540.1 13.7 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) CENP-B_dimeris PF09026.10 KIK47452.1 - 0.0079 16.6 1.1 0.016 15.6 1.1 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain OFeT_1 PF16955.5 KIK47452.1 - 0.025 14.3 0.4 0.048 13.4 0.4 1.4 1 0 0 1 1 1 0 Ferrous iron uptake permease, iron-lead transporter Rad51 PF08423.11 KIK47454.1 - 8e-20 71.2 0.0 1e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 KIK47454.1 - 8e-10 38.5 0.1 1.7e-09 37.4 0.1 1.6 1 1 0 1 1 1 1 KaiC RecA PF00154.21 KIK47454.1 - 3.2e-05 23.5 0.5 5.7e-05 22.7 0.5 1.4 1 1 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 KIK47454.1 - 0.00014 21.5 0.1 0.00037 20.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KIK47454.1 - 0.00016 21.1 0.1 0.00083 18.8 0.1 2.0 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_30 PF13604.6 KIK47454.1 - 0.02 14.6 0.0 0.36 10.5 0.0 2.4 1 1 1 2 2 2 0 AAA domain PSY3 PF16836.5 KIK47454.1 - 0.041 13.4 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description AAA_24 PF13479.6 KIK47454.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK47454.1 - 0.17 11.1 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Vault_4 PF17796.1 KIK47455.1 - 0.054 13.6 0.2 0.07 13.2 0.2 1.2 1 0 0 1 1 1 0 Major Vault Protein repeat domain FAD_binding_3 PF01494.19 KIK47456.1 - 1.8e-74 251.1 0.0 2.7e-74 250.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK47456.1 - 2.8e-06 26.8 0.1 5.1e-05 22.6 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK47456.1 - 3.3e-06 27.2 0.1 8.9e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIK47456.1 - 4.9e-06 25.5 0.6 5.5e-05 22.1 0.1 2.3 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 KIK47456.1 - 7.3e-06 25.3 0.1 1.6e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KIK47456.1 - 5.3e-05 22.6 0.0 0.00042 19.7 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIK47456.1 - 0.00042 19.8 0.1 0.00082 18.8 0.1 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 KIK47456.1 - 0.00056 19.6 0.0 0.0017 18.0 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KIK47456.1 - 0.0031 16.6 0.1 0.0047 16.1 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KIK47456.1 - 0.0037 17.8 0.0 0.23 12.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIK47456.1 - 0.0039 16.1 0.0 0.0062 15.4 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.17 KIK47456.1 - 0.0066 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KIK47456.1 - 0.014 14.4 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KIK47456.1 - 0.017 15.1 0.2 0.047 13.7 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KIK47456.1 - 0.037 13.3 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KIK47456.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Cellulase PF00150.18 KIK47457.1 - 1e-25 90.7 5.3 1.3e-25 90.4 5.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KIK47457.1 - 0.0026 16.9 0.0 0.007 15.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KIK47457.1 - 0.0039 16.6 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase DHDPS PF00701.22 KIK47458.1 - 7.4e-40 136.5 0.0 8.8e-40 136.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.6 KIK47458.1 - 0.013 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Dynamin_N PF00350.23 KIK47459.1 - 2.8e-43 147.9 0.0 7.3e-43 146.5 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KIK47459.1 - 5.9e-11 42.1 0.0 3.1e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 KIK47459.1 - 5e-05 23.4 0.0 0.00017 21.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KIK47459.1 - 0.028 14.2 0.4 0.059 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RecG_N PF17190.4 KIK47459.1 - 0.052 14.3 1.1 3.6 8.4 0.1 3.5 3 0 0 3 3 3 0 RecG N-terminal helical domain AAA_15 PF13175.6 KIK47459.1 - 0.065 12.9 0.3 0.17 11.5 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain YtxH PF12732.7 KIK47459.1 - 3.1 8.4 4.9 11 6.6 0.0 3.6 4 1 0 4 4 4 0 YtxH-like protein SCP2 PF02036.17 KIK47460.1 - 1.5e-22 80.0 2.3 1.8e-22 79.7 2.3 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KIK47460.1 - 9.3e-07 29.2 1.0 1.4e-06 28.6 1.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KIK47460.1 - 0.02 15.3 0.1 0.027 14.9 0.1 1.3 1 0 0 1 1 1 0 Sterol carrier protein domain FtsJ PF01728.19 KIK47460.1 - 0.024 14.8 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase NTP_transf_9 PF04248.12 KIK47461.1 - 5.5e-43 144.8 0.1 1.8e-29 101.5 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF427) eIF-5_eIF-2B PF01873.17 KIK47462.1 - 1.1e-37 128.5 0.0 2.3e-37 127.4 0.0 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KIK47462.1 - 4.3e-22 78.0 4.3 6.5e-22 77.5 0.1 2.9 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon DUF997 PF06196.12 KIK47464.1 - 0.21 11.6 2.9 0.35 10.9 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF997) Maf1 PF09174.10 KIK47465.1 - 2.2e-40 138.6 0.2 1e-34 120.2 0.0 2.2 2 0 0 2 2 2 2 Maf1 regulator Dabb PF07876.12 KIK47467.1 - 6.6e-14 52.3 0.0 7.2e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain PLDc_2 PF13091.6 KIK47468.1 - 1.4e-14 54.1 0.0 9.8e-07 28.7 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KIK47468.1 - 1.1e-12 47.6 0.6 3.3e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PX PF00787.24 KIK47468.1 - 2.8e-11 43.4 3.7 1.1e-09 38.3 0.4 3.6 3 0 0 3 3 3 1 PX domain PH PF00169.29 KIK47468.1 - 0.081 13.4 0.2 1.4 9.5 0.1 2.5 2 0 0 2 2 2 0 PH domain F-box-like PF12937.7 KIK47469.1 - 1.6e-09 37.5 1.5 2.4e-09 36.9 0.4 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK47469.1 - 0.0034 17.2 0.1 0.01 15.7 0.1 1.8 1 0 0 1 1 1 1 F-box domain RRM_1 PF00076.22 KIK47472.1 - 1.1e-49 166.1 0.0 9.6e-19 67.0 0.0 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIK47472.1 - 2.3e-11 43.4 0.0 0.00094 19.0 0.0 4.6 4 0 0 4 4 4 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KIK47472.1 - 2.3e-07 30.7 0.0 0.78 9.8 0.0 3.6 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KIK47472.1 - 0.00047 20.2 0.0 11 6.2 0.0 3.7 3 0 0 3 3 3 1 RNA recognition motif Suf PF05843.14 KIK47472.1 - 0.00053 20.1 0.0 0.0019 18.3 0.0 2.0 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) Nup35_RRM PF05172.13 KIK47472.1 - 0.021 14.8 0.0 0.16 12.0 0.0 2.2 1 1 1 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KIK47472.1 - 0.028 14.4 0.1 4.7 7.3 0.1 3.5 3 0 0 3 3 3 0 RNA binding motif RPN7 PF10602.9 KIK47472.1 - 0.052 13.2 0.2 0.46 10.2 0.0 2.3 2 0 0 2 2 2 0 26S proteasome subunit RPN7 RET_CLD3 PF17812.1 KIK47472.1 - 0.063 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 RET Cadherin like domain 3 TPR_14 PF13428.6 KIK47472.1 - 0.55 11.2 15.3 2.3 9.3 0.0 5.7 4 2 1 5 5 5 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KIK47472.1 - 0.56 9.3 8.0 2.8 7.0 0.0 3.8 3 2 1 4 4 4 0 NRDE-2, necessary for RNA interference SKN1 PF03935.15 KIK47473.1 - 1.8e-195 650.2 7.9 2.1e-195 649.9 7.9 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) ThiF PF00899.21 KIK47474.1 - 2.4e-33 115.5 0.0 3.3e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family DUF2527 PF10736.9 KIK47475.1 - 0.039 13.8 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Fungal_trans PF04082.18 KIK47476.1 - 1e-19 70.6 0.0 1.6e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK47476.1 - 1.5e-06 28.2 10.0 3.2e-06 27.2 10.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPR_3 PF13812.6 KIK47477.1 - 0.00022 21.2 0.0 0.00072 19.6 0.0 1.9 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 KIK47477.1 - 0.00073 19.7 0.0 0.0031 17.7 0.0 2.2 1 0 0 1 1 1 1 PPR repeat family PPR PF01535.20 KIK47477.1 - 0.00078 19.5 0.2 33 5.0 0.0 5.0 4 0 0 4 4 4 1 PPR repeat TPR_19 PF14559.6 KIK47477.1 - 0.062 13.8 0.1 0.36 11.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR_1 PF12854.7 KIK47477.1 - 0.12 12.2 0.1 0.4 10.4 0.0 2.0 2 0 0 2 2 2 0 PPR repeat GRASP55_65 PF04495.14 KIK47478.1 - 3.8e-61 205.4 0.0 5.1e-44 149.9 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KIK47478.1 - 0.00095 19.0 0.2 0.0066 16.3 0.0 2.4 3 0 0 3 3 3 1 PDZ domain PDZ_2 PF13180.6 KIK47478.1 - 0.0099 16.2 0.0 3.2 8.1 0.0 2.4 2 0 0 2 2 2 2 PDZ domain ICMT PF04140.14 KIK47479.1 - 8.5e-06 26.1 0.2 1.9e-05 25.0 0.2 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK47479.1 - 0.00019 21.8 0.1 0.00045 20.6 0.1 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase MATH PF00917.26 KIK47480.1 - 8.1e-06 26.0 0.4 1.7e-05 25.0 0.4 1.5 1 0 0 1 1 1 1 MATH domain BTB PF00651.31 KIK47480.1 - 0.00092 19.4 0.1 3.2 8.0 0.0 2.9 3 0 0 3 3 3 2 BTB/POZ domain zf-MYND PF01753.18 KIK47481.1 - 0.00014 21.9 9.6 0.00037 20.5 9.6 1.7 1 0 0 1 1 1 1 MYND finger Mur_ligase_M PF08245.12 KIK47482.1 - 1.3e-06 28.6 0.1 4e-06 27.0 0.1 2.0 1 1 0 1 1 1 1 Mur ligase middle domain Peptidase_C48 PF02902.19 KIK47486.1 - 1.1e-32 113.7 0.1 2.4e-19 70.0 0.1 2.5 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain BSP_II PF05432.11 KIK47486.1 - 5.8 6.5 8.2 2.5 7.7 0.4 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Acetyltransf_1 PF00583.25 KIK47488.1 - 0.0025 18.0 0.0 0.0041 17.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family SH3_9 PF14604.6 KIK47488.1 - 0.021 14.7 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Acetyltransf_7 PF13508.7 KIK47488.1 - 0.15 12.5 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SMC_N PF02463.19 KIK47489.1 - 1.2e-27 96.9 0.0 1.9e-27 96.1 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIK47489.1 - 6.2e-12 46.4 30.8 6.2e-12 46.4 30.8 6.0 3 2 0 3 3 2 1 AAA domain AAA_15 PF13175.6 KIK47489.1 - 7.7e-09 35.7 8.6 7.7e-09 35.7 8.6 3.7 3 2 0 3 3 2 1 AAA ATPase domain AAA_21 PF13304.6 KIK47489.1 - 2.3e-07 30.9 0.5 0.00076 19.4 0.5 3.0 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIK47489.1 - 0.00036 20.2 0.0 0.0009 18.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain TMF_TATA_bd PF12325.8 KIK47489.1 - 0.0092 16.2 3.3 0.0092 16.2 3.3 7.2 3 2 2 6 6 3 1 TATA element modulatory factor 1 TATA binding Baculo_PEP_C PF04513.12 KIK47489.1 - 0.039 14.0 0.3 0.039 14.0 0.3 4.5 3 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus TcdB_N PF12918.7 KIK47489.1 - 0.064 13.5 4.2 9 6.7 0.2 3.8 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain ABC_tran PF00005.27 KIK47489.1 - 0.1 13.1 0.1 0.1 13.1 0.1 5.6 3 2 0 3 3 2 0 ABC transporter PI_PP_I PF18363.1 KIK47489.1 - 1.5 9.0 4.0 35 4.7 0.0 3.4 3 0 0 3 3 3 0 Phosphoinositide phosphatase insertion domain Sacchrp_dh_NADP PF03435.18 KIK47489.1 - 8 6.7 6.9 2.2 8.5 0.5 3.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain E1_dh PF00676.20 KIK47490.1 - 6.3e-81 271.6 0.0 7.5e-81 271.4 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component GFO_IDH_MocA PF01408.22 KIK47491.1 - 5.2e-19 69.2 0.0 7.6e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIK47491.1 - 0.00018 21.5 0.0 0.00038 20.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 KIK47491.1 - 0.0029 18.0 0.0 0.0057 17.1 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DNAPolymera_Pol PF11590.8 KIK47491.1 - 0.027 14.3 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol Mit_KHE1 PF10173.9 KIK47493.1 - 4.2e-54 183.5 0.0 6.1e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related BCD PF15461.6 KIK47493.1 - 0.057 12.9 0.4 0.093 12.2 0.4 1.2 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase Zip PF02535.22 KIK47497.1 - 1.8e-18 66.9 13.4 3.8e-16 59.2 13.4 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter mRNA_triPase PF02940.15 KIK47498.1 - 2.7e-51 174.4 0.8 3.3e-51 174.1 0.8 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Rad60-SLD PF11976.8 KIK47499.1 - 6.4e-09 35.5 0.1 1.4e-06 28.0 0.3 3.0 2 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DWNN PF08783.11 KIK47500.1 - 0.034 14.4 0.1 0.11 12.8 0.1 1.9 1 0 0 1 1 1 0 DWNN domain YabA PF06156.13 KIK47500.1 - 3.9 8.2 4.5 4.7 7.9 0.4 2.8 2 1 1 3 3 3 0 Initiation control protein YabA Endonuclease_7 PF02945.15 KIK47501.1 - 1.9 8.5 5.7 13 5.8 0.1 2.4 2 0 0 2 2 2 0 Recombination endonuclease VII MIP PF00230.20 KIK47502.1 - 7.5e-49 166.5 9.6 9.2e-49 166.2 9.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 KIK47504.1 - 1e-50 172.6 7.8 1.3e-50 172.3 7.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein EamA PF00892.20 KIK47504.1 - 0.063 13.4 0.6 0.063 13.4 0.6 3.3 2 2 2 4 4 4 0 EamA-like transporter family DUF962 PF06127.11 KIK47505.1 - 0.06 13.4 0.0 0.45 10.6 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Homeodomain PF00046.29 KIK47506.1 - 1.1e-07 31.6 0.5 1.9e-07 30.8 0.5 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KIK47506.1 - 0.029 14.3 0.0 0.085 12.8 0.0 1.8 1 0 0 1 1 1 0 Homeobox KN domain WD40 PF00400.32 KIK47507.1 - 0.0014 19.4 0.0 0.019 15.9 0.0 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat Nup160 PF11715.8 KIK47507.1 - 0.032 12.9 0.0 0.048 12.3 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 PH PF00169.29 KIK47509.1 - 1.2e-06 28.9 0.8 3.1e-06 27.6 0.8 1.7 1 0 0 1 1 1 1 PH domain RA PF00788.23 KIK47509.1 - 0.003 18.2 0.0 0.0087 16.7 0.0 1.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PH_11 PF15413.6 KIK47509.1 - 0.075 13.5 0.7 0.21 12.1 0.7 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain POB3_N PF17292.2 KIK47510.1 - 1.3e-33 115.2 0.3 1.6e-28 99.0 0.1 3.2 2 1 1 3 3 3 2 POB3-like N-terminal PH domain SSrecog PF03531.14 KIK47510.1 - 3.1e-26 91.1 0.0 1.2e-25 89.2 0.0 2.1 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KIK47510.1 - 6.7e-21 74.5 0.0 4.9e-20 71.7 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CH PF00307.31 KIK47511.1 - 3.1e-46 156.0 0.0 2.9e-24 85.4 0.0 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KIK47511.1 - 3.9e-15 55.4 0.0 2.7e-09 36.7 0.0 2.5 2 0 0 2 2 2 2 CAMSAP CH domain EFhand_Ca_insen PF08726.10 KIK47511.1 - 1.7e-13 50.4 0.0 6.4e-13 48.6 0.0 2.1 1 0 0 1 1 1 1 Ca2+ insensitive EF hand Spectrin PF00435.21 KIK47511.1 - 0.00044 20.7 2.7 0.22 12.0 0.1 3.1 2 1 1 3 3 3 2 Spectrin repeat EF-hand_6 PF13405.6 KIK47511.1 - 0.11 12.5 0.0 0.35 10.9 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.6 KIK47511.1 - 0.11 12.3 0.0 0.6 10.0 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair Baculo_PEP_C PF04513.12 KIK47511.1 - 0.12 12.5 5.5 0.15 12.1 0.6 3.0 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 KIK47511.1 - 0.17 10.8 5.6 0.035 13.0 1.5 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein COG2 PF06148.11 KIK47511.1 - 0.39 10.8 2.7 0.42 10.7 0.6 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4355 PF14265.6 KIK47511.1 - 3.9 7.7 6.1 13 6.1 1.2 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4355) Exonuc_VII_L PF02601.15 KIK47511.1 - 4.8 6.7 8.1 31 4.0 8.1 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit Aldo_ket_red PF00248.21 KIK47512.1 - 5.2e-08 32.4 0.0 2e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Transp_Tc5_C PF04236.15 KIK47512.1 - 0.076 13.4 0.1 0.98 9.8 0.1 2.2 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Scm3 PF10384.9 KIK47513.1 - 2.2e-10 40.1 0.2 7.2e-10 38.5 0.2 1.9 1 0 0 1 1 1 1 Centromere protein Scm3 Methyltransf_11 PF08241.12 KIK47514.1 - 9.6e-12 45.4 0.0 1.6e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK47514.1 - 1.8e-07 31.8 0.0 4e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK47514.1 - 9.6e-07 28.8 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK47514.1 - 0.0005 20.8 0.0 0.0017 19.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 KIK47514.1 - 0.049 13.3 0.0 0.76 9.3 0.0 2.1 1 1 1 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ribosomal_S21 PF01165.20 KIK47514.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S21 Rhodanese PF00581.20 KIK47515.1 - 3.6e-08 33.9 0.0 4.7e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF3767 PF12597.8 KIK47516.1 - 2.2e-18 65.9 0.4 2.6e-18 65.7 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) TraC PF07820.12 KIK47516.1 - 0.0047 17.2 0.3 0.007 16.7 0.3 1.2 1 0 0 1 1 1 1 TraC-like protein Bombesin PF02044.17 KIK47516.1 - 0.054 13.6 0.6 0.12 12.5 0.6 1.6 1 0 0 1 1 1 0 Bombesin-like peptide DUF5486 PF17588.2 KIK47516.1 - 0.062 13.2 0.2 0.087 12.7 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5486) Porin_3 PF01459.22 KIK47517.1 - 8.3e-74 248.4 3.8 9.3e-74 248.3 3.8 1.0 1 0 0 1 1 1 1 Eukaryotic porin Aldo_ket_red PF00248.21 KIK47518.1 - 4.2e-61 206.7 0.1 4.8e-61 206.5 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1688 PF07958.11 KIK47518.1 - 0.095 11.4 0.0 0.83 8.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1688) Mon1 PF03164.14 KIK47519.1 - 1.4e-118 396.5 0.0 1.9e-118 396.1 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Aldo_ket_red PF00248.21 KIK47520.1 - 9.2e-67 225.3 0.2 1.1e-66 225.1 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family IMPa_N_2 PF18650.1 KIK47520.1 - 0.098 11.9 0.1 0.19 11.0 0.1 1.5 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain IGR PF09597.10 KIK47521.1 - 4.4e-21 74.7 0.2 6.4e-21 74.2 0.2 1.3 1 0 0 1 1 1 1 IGR protein motif zf-C2H2_4 PF13894.6 KIK47522.1 - 3.4e-05 24.3 2.8 0.37 11.8 0.0 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK47522.1 - 0.00039 20.7 7.6 0.018 15.5 0.0 3.6 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-BED PF02892.15 KIK47522.1 - 0.00074 19.5 0.5 0.088 12.8 0.0 2.5 2 0 0 2 2 2 1 BED zinc finger Rubredoxin PF00301.20 KIK47522.1 - 0.18 11.9 3.0 0.61 10.2 3.0 1.9 1 1 1 2 2 2 0 Rubredoxin zf-Di19 PF05605.12 KIK47522.1 - 0.61 10.4 3.5 0.38 11.1 0.6 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KIK47522.1 - 2.4 8.7 12.1 0.62 10.6 0.2 3.8 4 0 0 4 4 4 0 Zinc-finger double domain Amidohydro_1 PF01979.20 KIK47524.1 - 9.8e-52 176.4 0.0 1.1e-51 176.2 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIK47524.1 - 3.1e-07 30.2 0.0 4.9e-05 23.0 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family UPF0172 PF03665.13 KIK47525.1 - 1.2e-55 188.5 0.0 1.4e-55 188.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 KIK47525.1 - 0.00035 20.5 0.0 0.00069 19.6 0.0 1.5 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease EBP PF05241.12 KIK47526.1 - 9.1e-68 227.2 8.0 1.1e-67 227.0 8.0 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2781 PF10914.8 KIK47526.1 - 0.12 12.8 8.5 0.14 12.5 7.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2781) GPI-anchored PF10342.9 KIK47527.1 - 0.031 15.0 0.0 0.036 14.8 0.0 1.1 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Endonuc-HincII PF09226.11 KIK47527.1 - 0.094 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease HincII HEAT_EZ PF13513.6 KIK47531.1 - 0.037 14.6 1.6 13 6.4 0.2 3.1 2 0 0 2 2 2 0 HEAT-like repeat GPI-anchored PF10342.9 KIK47532.1 - 0.00022 21.9 0.0 0.00034 21.3 0.0 1.3 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CTP_transf_like PF01467.26 KIK47533.1 - 0.12 12.5 0.0 0.18 12.0 0.0 1.3 1 1 0 1 1 1 0 Cytidylyltransferase-like RRP36 PF06102.12 KIK47534.1 - 1.3e-38 132.6 15.7 2.3e-38 131.8 15.7 1.4 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 Tcp11 PF05794.13 KIK47535.1 - 8.3e-82 275.6 0.0 1.2e-81 275.1 0.0 1.2 1 0 0 1 1 1 1 T-complex protein 11 ATP-synt_ab PF00006.25 KIK47536.1 - 2.6e-67 226.6 0.0 3.6e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KIK47536.1 - 1.4e-12 47.9 0.5 2.6e-12 47.1 0.5 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain TFCD_C PF12612.8 KIK47537.1 - 3.9e-42 144.2 1.5 1e-40 139.6 0.0 3.4 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 KIK47537.1 - 2.3e-06 27.4 16.7 0.022 15.0 0.0 9.1 10 0 0 10 10 10 2 HEAT repeat HEAT_2 PF13646.6 KIK47537.1 - 2.8e-05 24.4 2.2 1.1 9.7 0.0 5.0 4 0 0 4 4 4 2 HEAT repeats Cnd1 PF12717.7 KIK47537.1 - 0.0027 17.8 0.1 0.046 13.8 0.0 3.1 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KIK47537.1 - 0.015 15.5 0.0 0.83 9.9 0.0 3.4 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KIK47537.1 - 0.065 11.8 1.7 13 4.2 0.0 4.4 4 1 1 5 5 5 0 Adaptin N terminal region BUD22 PF09073.10 KIK47538.1 - 1.5e-69 235.4 25.2 1.7e-68 232.0 25.2 1.9 1 1 0 1 1 1 1 BUD22 PP2C_C PF07830.13 KIK47538.1 - 0.11 13.0 0.2 0.32 11.5 0.2 1.8 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain EMC3_TMCO1 PF01956.16 KIK47538.1 - 5.5 6.7 6.8 0.28 10.9 0.8 1.8 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like zf-HIT PF04438.16 KIK47539.1 - 0.19 11.6 6.1 1.3 9.0 6.1 2.4 1 1 0 1 1 1 0 HIT zinc finger zf-MYND PF01753.18 KIK47539.1 - 0.62 10.2 9.0 1.5 8.9 9.0 1.7 1 0 0 1 1 1 0 MYND finger PP2C PF00481.21 KIK47542.1 - 1.2e-78 264.3 0.0 2.1e-78 263.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KIK47542.1 - 0.0053 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C CS PF04969.16 KIK47543.1 - 3.5e-10 40.8 0.0 8e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 CS domain FHA PF00498.26 KIK47544.1 - 3.7e-16 59.2 0.0 7.4e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIK47544.1 - 1.1e-05 25.6 0.0 0.00047 20.4 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Lipase_3 PF01764.25 KIK47546.1 - 1.8e-23 83.0 0.0 2.5e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIK47546.1 - 0.00047 20.8 0.1 0.001 19.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KIK47546.1 - 0.0016 18.2 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein UPF0227 PF05728.12 KIK47546.1 - 0.0052 16.7 0.0 0.0084 16.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) DUF915 PF06028.11 KIK47546.1 - 0.029 13.7 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2974 PF11187.8 KIK47546.1 - 0.034 13.7 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Thioesterase PF00975.20 KIK47546.1 - 0.1 12.7 0.0 4.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain Zn_clus PF00172.18 KIK47547.1 - 2.1e-08 34.1 11.8 4.4e-08 33.1 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CRD PF17979.1 KIK47548.1 - 1.3e-11 44.9 0.0 1.3e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 Cysteine rich domain with multizinc binding regions zf-C3HC4_2 PF13923.6 KIK47548.1 - 6.5e-06 25.9 12.2 6.5e-06 25.9 12.2 3.8 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK47548.1 - 2.1e-05 24.8 13.2 2.1e-05 24.8 13.2 4.0 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIK47548.1 - 0.00044 20.0 11.1 0.00044 20.0 11.1 3.8 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK47548.1 - 0.001 18.9 10.9 0.001 18.9 10.9 3.7 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KIK47548.1 - 0.012 15.5 7.4 0.012 15.5 7.4 2.6 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 KIK47548.1 - 0.68 10.0 19.9 1.3 9.1 11.3 3.8 3 0 0 3 3 3 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 KIK47548.1 - 3.2 7.9 9.7 1.4 9.0 3.7 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KIK47548.1 - 4.7 7.2 30.3 0.046 13.7 12.1 3.6 4 0 0 4 4 4 0 zinc-RING finger domain Kelch_5 PF13854.6 KIK47549.1 - 1.2e-17 63.5 1.7 4.8e-05 23.3 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 KIK47549.1 - 3.1e-15 55.8 2.6 0.00035 20.7 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KIK47549.1 - 4.2e-15 55.1 0.5 0.00025 20.6 0.0 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 KIK47549.1 - 1e-14 53.8 1.0 0.00065 19.6 0.1 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 KIK47549.1 - 6.4e-12 45.3 4.5 0.00081 19.4 0.0 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KIK47549.1 - 2.7e-10 40.3 5.2 3.3e-07 30.4 0.0 5.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Bac_small_YrzI PF09501.10 KIK47549.1 - 0.66 10.1 5.5 1.4 9.1 5.5 1.5 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) Kri1 PF05178.12 KIK47549.1 - 1 10.0 8.6 1.9 9.1 8.6 1.4 1 0 0 1 1 1 0 KRI1-like family Putative_PNPOx PF01243.20 KIK47550.1 - 1.1e-24 86.4 0.0 2e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 KIK47550.1 - 6.6e-18 64.5 3.8 1.3e-17 63.6 3.8 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 KIK47550.1 - 1.1e-05 26.0 0.2 1.7e-05 25.4 0.2 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 KIK47550.1 - 0.022 14.4 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like Aldo_ket_red PF00248.21 KIK47551.1 - 3.7e-70 236.5 0.1 4.2e-70 236.3 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cerato-platanin PF07249.12 KIK47552.1 - 3.7e-36 123.8 1.8 4.4e-36 123.6 1.8 1.0 1 0 0 1 1 1 1 Cerato-platanin Plant_tran PF04827.14 KIK47552.1 - 0.08 12.5 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Plant transposon protein PDDEXK_6 PF04720.12 KIK47552.1 - 0.22 11.5 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 PDDEXK-like family of unknown function Glycolytic PF00274.19 KIK47554.1 - 0.0089 14.8 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Linker_histone PF00538.19 KIK47556.1 - 4.2e-09 36.6 0.0 7.9e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family DUF4200 PF13863.6 KIK47558.1 - 0.025 15.0 2.8 0.04 14.3 0.5 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) FKBP_C PF00254.28 KIK47559.1 - 5.2e-30 103.6 0.0 6e-30 103.4 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4801 PF16059.5 KIK47565.1 - 0.043 13.8 1.2 0.064 13.2 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4801) OGFr_N PF04664.13 KIK47568.1 - 9.4e-62 208.2 0.5 1.2e-61 207.9 0.5 1.1 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region DUF727 PF05303.12 KIK47569.1 - 3.3e-06 27.1 0.0 0.00063 19.8 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF727) Sec1 PF00995.23 KIK47570.1 - 6.4e-121 405.4 0.0 7.3e-121 405.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF2390 PF09523.10 KIK47571.1 - 0.071 13.4 0.6 0.13 12.5 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Importin_rep_4 PF18808.1 KIK47571.1 - 6.5 7.1 7.6 7.7 6.9 2.5 2.9 2 1 0 2 2 2 0 Importin repeat ABC2_membrane_3 PF12698.7 KIK47572.1 - 0.04 13.0 4.1 0.26 10.3 1.4 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein LapA_dom PF06305.11 KIK47572.1 - 3.1 7.7 5.2 9.3 6.2 5.2 1.8 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF3752 PF12572.8 KIK47573.1 - 0.044 14.3 0.2 0.09 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) ParA PF10609.9 KIK47576.1 - 1.4e-87 293.2 0.0 1.8e-87 292.9 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KIK47576.1 - 3.3e-08 33.6 0.0 5.5e-07 29.7 0.0 2.4 3 1 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KIK47576.1 - 2.1e-05 23.9 0.4 0.00089 18.5 0.2 2.4 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.6 KIK47576.1 - 5.7e-05 23.1 0.0 0.0041 17.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 KIK47576.1 - 7.3e-05 22.2 0.0 0.00069 19.0 0.1 2.0 2 0 0 2 2 2 1 ATPase MipZ CBP_BcsQ PF06564.12 KIK47576.1 - 0.045 13.2 0.0 0.084 12.3 0.0 1.4 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_22 PF13401.6 KIK47576.1 - 0.064 13.5 0.1 0.19 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIK47576.1 - 0.17 12.2 0.5 0.52 10.7 0.2 1.9 2 0 0 2 2 2 0 AAA ATPase domain F-box-like PF12937.7 KIK47577.1 - 7.1e-06 25.8 0.4 2.6e-05 24.0 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK47577.1 - 0.00051 19.8 0.3 0.0019 18.1 0.3 1.9 1 0 0 1 1 1 1 F-box domain NmrA PF05368.13 KIK47578.1 - 6.8e-28 97.8 0.0 8.7e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK47578.1 - 2.3e-14 53.7 0.0 3.6e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KIK47578.1 - 6.1e-05 22.3 0.0 0.0083 15.3 0.0 2.5 2 0 0 2 2 2 2 Male sterility protein Epimerase PF01370.21 KIK47578.1 - 9.2e-05 22.0 0.0 0.0032 17.0 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF2244 PF10003.9 KIK47580.1 - 0.05 13.3 1.0 2.7 7.7 0.1 2.6 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Chitin_synth_1 PF01644.17 KIK47581.1 - 1.6e-71 239.5 0.2 2.5e-71 238.9 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KIK47581.1 - 1e-26 92.7 0.0 2.9e-26 91.2 0.0 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KIK47581.1 - 2.9e-23 82.3 0.1 1.3e-18 67.0 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KIK47581.1 - 0.00036 20.5 11.3 0.0074 16.2 11.3 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Pkinase PF00069.25 KIK47582.1 - 2.5e-26 92.6 0.0 3e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK47582.1 - 9.4e-14 51.3 0.0 1.2e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK47582.1 - 2.1e-09 36.7 0.1 3.2e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK47582.1 - 0.0011 19.0 0.0 0.0069 16.3 0.0 2.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KIK47582.1 - 0.016 14.2 0.1 0.023 13.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KIK47582.1 - 0.075 12.4 0.5 0.12 11.7 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-met2 PF12907.7 KIK47583.1 - 0.17 12.0 3.2 0.24 11.6 0.3 2.6 3 0 0 3 3 3 0 Zinc-binding tRNA-synt_2b PF00587.25 KIK47585.1 - 1.7e-23 83.5 0.0 4.4e-23 82.2 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KIK47585.1 - 7.5e-07 29.4 0.4 1.3e-06 28.6 0.4 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Rep_fac_C PF08542.11 KIK47586.1 - 1e-26 93.1 0.0 2.4e-26 92.0 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KIK47586.1 - 5.2e-12 45.9 0.0 5.8e-10 39.2 0.0 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 KIK47586.1 - 5.6e-12 46.2 0.0 9.6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KIK47586.1 - 1.4e-06 28.4 0.0 2.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK47586.1 - 4.8e-06 26.9 0.0 0.0028 17.9 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 KIK47586.1 - 1.5e-05 25.4 0.0 0.00033 21.1 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KIK47586.1 - 0.00013 21.8 0.0 0.00028 20.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KIK47586.1 - 0.00016 21.5 0.0 0.00028 20.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KIK47586.1 - 0.00059 19.7 0.0 0.0009 19.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 KIK47586.1 - 0.00061 19.8 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 KIK47586.1 - 0.0024 17.7 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit MeaB PF03308.16 KIK47586.1 - 0.0038 16.2 0.0 0.0082 15.2 0.0 1.5 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Mg_chelatase PF01078.21 KIK47586.1 - 0.0049 16.3 0.0 0.026 13.9 0.0 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_assoc_2 PF16193.5 KIK47586.1 - 0.0077 16.5 0.0 0.019 15.3 0.0 1.8 2 0 0 2 2 1 1 AAA C-terminal domain AAA_11 PF13086.6 KIK47586.1 - 0.02 14.7 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KIK47586.1 - 0.022 14.5 0.0 0.093 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KIK47586.1 - 0.036 14.0 0.1 0.08 12.8 0.1 1.6 1 1 0 1 1 1 0 NTPase AAA_18 PF13238.6 KIK47586.1 - 0.044 14.3 0.0 0.52 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KIK47586.1 - 0.08 12.4 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SRP54 PF00448.22 KIK47586.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 KIK47586.1 - 0.085 13.3 0.0 0.39 11.1 0.0 2.1 1 1 0 1 1 1 0 RNA helicase DMA PF03474.14 KIK47586.1 - 0.086 12.5 0.3 22 4.8 0.0 3.0 3 0 0 3 3 3 0 DMRTA motif AAA_19 PF13245.6 KIK47586.1 - 0.1 12.9 0.2 0.34 11.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIK47586.1 - 0.18 12.3 0.1 0.56 10.7 0.1 1.6 1 1 0 1 1 1 0 ABC transporter DSHCT PF08148.12 KIK47587.1 - 9.5e-53 178.2 1.1 2.2e-52 177.0 1.1 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KIK47587.1 - 4.2e-32 110.8 0.0 7.7e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 KIK47587.1 - 2.4e-29 103.1 0.0 3.9e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KIK47587.1 - 7.9e-20 71.3 0.1 3.5e-19 69.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KIK47587.1 - 1.8e-06 28.1 0.0 3.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIK47587.1 - 1.2e-05 25.6 0.0 4.1e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain HTH_17 PF12728.7 KIK47588.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain NCBP3 PF10309.9 KIK47590.1 - 1.8e-06 27.7 0.0 2.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 KIK47590.1 - 0.027 14.5 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA binding domain SIKE PF05769.11 KIK47591.1 - 1.2e-08 35.1 9.5 2.9e-06 27.3 1.8 2.4 2 0 0 2 2 2 2 SIKE family ETC_C1_NDUFA4 PF04800.12 KIK47591.1 - 0.096 13.0 0.6 0.27 11.5 0.6 1.7 1 0 0 1 1 1 0 ETC complex I subunit conserved region NYD-SP28_assoc PF14775.6 KIK47591.1 - 1.3 9.2 5.1 1.5 8.9 0.5 2.5 2 0 0 2 2 2 0 Sperm tail C-terminal domain RTP1_C2 PF10304.9 KIK47595.1 - 0.034 13.8 0.2 0.065 12.9 0.2 1.5 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 MMM1 PF10296.9 KIK47596.1 - 3.8e-06 26.2 0.0 9.5e-06 24.9 0.0 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 PH_9 PF15410.6 KIK47596.1 - 0.046 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PH PF00169.29 KIK47596.1 - 0.15 12.6 0.0 1.1 9.8 0.0 2.4 1 1 0 1 1 1 0 PH domain MARVEL PF01284.23 KIK47598.1 - 0.038 14.0 22.5 0.11 12.5 21.2 2.2 1 1 0 1 1 1 0 Membrane-associating domain Nucleo_P87 PF07267.11 KIK47598.1 - 6.9 5.4 4.8 9 5.0 4.8 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 dsrm PF00035.26 KIK47600.1 - 0.042 14.6 0.0 0.078 13.7 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif dsrm PF00035.26 KIK47601.1 - 7.1e-07 29.8 0.0 8.1e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif dsrm PF00035.26 KIK47602.1 - 3.3e-06 27.7 0.1 3.9e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif UCH PF00443.29 KIK47604.1 - 1.1e-27 97.2 0.0 1.5e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KIK47604.1 - 3.7e-11 43.2 0.1 7.1e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Rsm22 PF09243.10 KIK47605.1 - 5.1e-47 160.4 0.0 1.1e-44 152.8 0.0 2.7 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 DUF2499 PF10693.9 KIK47605.1 - 0.14 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2499) Ribosomal_L1 PF00687.21 KIK47606.1 - 3.4e-21 75.9 0.0 6.2e-21 75.1 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family MRP-L28 PF09812.9 KIK47607.1 - 5.7e-10 39.6 8.2 5.2e-07 29.9 4.2 2.4 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L28 PCI PF01399.27 KIK47608.1 - 3.1e-18 66.2 0.3 7.3e-18 65.0 0.3 1.7 1 0 0 1 1 1 1 PCI domain DUF5517 PF17639.2 KIK47608.1 - 0.0079 16.5 6.1 0.024 14.9 0.6 3.2 3 1 0 3 3 3 1 Family of unknown function (DUF5517) FSIP1 PF15554.6 KIK47608.1 - 0.9 8.6 6.0 3.3 6.7 0.1 2.5 3 0 0 3 3 3 0 FSIP1 family Bromodomain PF00439.25 KIK47610.1 - 3.4e-58 193.7 0.2 1.8e-20 72.8 0.0 3.6 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.20 KIK47610.1 - 1.1e-09 38.2 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KIK47610.1 - 0.0047 17.1 0.1 2.3 8.4 0.0 2.5 1 1 0 2 2 2 2 Peptidase M1 N-terminal domain LTV PF04180.14 KIK47611.1 - 6.1e-99 332.3 13.1 3.8e-93 313.3 10.4 2.1 1 1 1 2 2 2 2 Low temperature viability protein PIP5K PF01504.18 KIK47612.1 - 7.3e-47 159.9 0.4 4.1e-38 131.2 0.3 2.4 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KIK47612.1 - 1.8e-29 102.8 0.0 3e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KIK47612.1 - 2.3e-17 62.9 10.4 2.3e-17 62.9 10.4 2.3 3 0 0 3 3 3 1 FYVE zinc finger IBR PF01485.21 KIK47612.1 - 0.42 10.9 9.2 0.052 13.8 4.1 2.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Med11 PF10280.9 KIK47613.1 - 1.2e-10 41.9 0.0 1.4e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Mediator complex protein PreAtp-grasp PF18604.1 KIK47613.1 - 0.15 11.7 0.0 1.2 8.8 0.0 2.1 1 1 1 2 2 2 0 Pre ATP-grasp domain TBCA PF02970.16 KIK47614.1 - 2.2e-23 82.4 6.6 5.1e-23 81.2 6.6 1.6 1 1 0 1 1 1 1 Tubulin binding cofactor A DUF2252 PF10009.9 KIK47614.1 - 0.0044 16.1 0.3 0.0052 15.9 0.3 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) MetOD2 PF18548.1 KIK47614.1 - 0.018 15.1 1.6 0.028 14.5 1.6 1.3 1 0 0 1 1 1 0 Metanogen output domain 2 FAD_binding_1 PF00667.20 KIK47614.1 - 0.055 13.0 0.2 0.069 12.7 0.2 1.4 1 1 0 1 1 1 0 FAD binding domain PX PF00787.24 KIK47615.1 - 0.1 12.6 0.2 0.12 12.4 0.2 1.1 1 0 0 1 1 1 0 PX domain HLH PF00010.26 KIK47616.1 - 9.5e-09 35.1 1.7 9.5e-09 35.1 1.7 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain UPF0242 PF06785.11 KIK47616.1 - 0.12 12.5 2.6 0.16 12.1 2.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus XAP5 PF04921.14 KIK47616.1 - 0.17 11.6 4.2 0.18 11.6 3.3 1.4 1 1 0 1 1 1 0 XAP5, circadian clock regulator CENP-F_leu_zip PF10473.9 KIK47616.1 - 0.19 11.8 5.7 0.26 11.3 5.7 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ribosomal_60s PF00428.19 KIK47616.1 - 0.22 12.1 2.6 1.1 9.9 1.4 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein MRP-S26 PF14943.6 KIK47616.1 - 9.7 6.1 10.4 2.3 8.1 2.0 2.1 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S26 HLH PF00010.26 KIK47618.1 - 2.1e-10 40.4 1.7 5.1e-10 39.2 1.7 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain FapA PF03961.13 KIK47618.1 - 0.86 8.1 2.3 1.2 7.7 2.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Ino80_Iec3 PF14612.6 KIK47618.1 - 1.6 9.3 7.6 7.9 7.1 2.1 2.2 2 0 0 2 2 2 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling ICL PF00463.21 KIK47621.1 - 2.9e-178 593.7 0.0 3.3e-178 593.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PRY PF13765.6 KIK47623.1 - 0.08 12.6 0.3 0.14 11.8 0.3 1.4 1 0 0 1 1 1 0 SPRY-associated domain Methyltransf_16 PF10294.9 KIK47626.1 - 2.2e-15 56.8 0.0 3.5e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 KIK47626.1 - 0.0051 16.6 0.0 0.0083 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FAM86 PF14904.6 KIK47626.1 - 0.0056 16.7 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function MTS PF05175.14 KIK47626.1 - 0.0091 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain UL42 PF17638.2 KIK47626.1 - 0.031 14.3 0.4 0.56 10.2 0.1 2.4 1 1 1 2 2 2 0 HCMV UL42 dsrm PF00035.26 KIK47628.1 - 6e-06 26.9 0.0 6.2e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif dsrm PF00035.26 KIK47629.1 - 0.00029 21.5 0.0 0.00029 21.5 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif dsrm PF00035.26 KIK47630.1 - 2.4e-07 31.3 0.0 3.6e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif MFS_1 PF07690.16 KIK47634.1 - 3.5e-16 59.1 23.7 7.7e-16 57.9 21.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Chordopox_A13L PF05961.11 KIK47634.1 - 0.1 12.9 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF1772 PF08592.11 KIK47634.1 - 0.33 11.3 9.4 3 8.2 0.7 3.3 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) Cpn60_TCP1 PF00118.24 KIK47635.1 - 1.3e-153 512.2 0.0 1.5e-153 512.0 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SNF2_N PF00176.23 KIK47637.1 - 8.8e-66 222.0 0.0 1.2e-65 221.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KIK47637.1 - 1.4e-14 53.8 0.0 3.7e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KIK47637.1 - 1.9e-13 50.7 0.0 4.2e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KIK47637.1 - 1.5e-06 27.9 17.0 2.4e-05 24.1 16.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KIK47637.1 - 2.5e-06 27.6 0.0 2.2e-05 24.5 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KIK47637.1 - 8.5e-06 25.5 16.5 8.5e-06 25.5 16.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK47637.1 - 4e-05 23.4 12.3 7.1e-05 22.6 12.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK47637.1 - 0.00016 21.9 15.1 0.00037 20.8 15.1 1.6 1 0 0 1 1 1 1 Ring finger domain DEAD PF00270.29 KIK47637.1 - 0.00032 20.5 0.0 0.0007 19.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.6 KIK47637.1 - 0.0054 16.7 16.7 0.013 15.5 15.7 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KIK47637.1 - 0.042 14.0 16.8 0.085 13.0 16.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KIK47637.1 - 0.16 12.0 13.4 0.3 11.1 13.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 KIK47637.1 - 1.1 9.3 6.6 0.5 10.4 4.0 1.7 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.20 KIK47637.1 - 1.5 8.6 11.1 3 7.7 11.1 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger WLM PF08325.10 KIK47638.1 - 1.4e-21 77.4 0.2 2.2e-21 76.8 0.2 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 KIK47638.1 - 2.1e-07 30.2 19.5 1e-05 24.7 0.8 4.1 4 0 0 4 4 4 3 Zn-finger in Ran binding protein and others SVIP PF15811.5 KIK47638.1 - 0.0042 17.5 3.8 0.65 10.5 0.0 2.7 2 0 0 2 2 2 2 Small VCP/p97-interacting protein DUF45 PF01863.17 KIK47638.1 - 0.16 12.0 0.5 0.24 11.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 DZR PF12773.7 KIK47638.1 - 1.2 9.2 15.0 0.85 9.7 8.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 KIK47638.1 - 3.9 7.9 10.7 0.75 10.2 2.1 3.1 2 1 1 3 3 3 0 C1 domain WLM PF08325.10 KIK47639.1 - 4.9e-14 52.9 0.0 5.3e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 WLM domain Ndc1_Nup PF09531.10 KIK47640.1 - 1.2 7.7 4.5 1.5 7.4 4.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Methyltransf_25 PF13649.6 KIK47642.1 - 2e-15 57.3 0.0 3.8e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK47642.1 - 9.7e-12 45.4 0.0 1.8e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK47642.1 - 1.9e-09 37.6 0.0 3.7e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK47642.1 - 8.3e-09 36.1 0.0 2.1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK47642.1 - 4.3e-08 33.1 0.0 1.1e-07 31.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK47642.1 - 9.9e-07 28.3 0.0 1.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KIK47642.1 - 3.8e-05 23.2 0.0 0.002 17.6 0.0 2.6 3 0 0 3 3 3 1 Putative methyltransferase MTS PF05175.14 KIK47642.1 - 0.00058 19.4 0.0 0.0031 17.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_29 PF03141.16 KIK47642.1 - 0.015 13.8 0.1 0.13 10.8 0.0 2.1 2 1 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.20 KIK47642.1 - 0.059 12.7 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 KIK47642.1 - 0.074 12.9 0.0 0.32 10.8 0.0 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_2 PF00891.18 KIK47642.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_32 PF13679.6 KIK47642.1 - 0.17 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SF3b10 PF07189.11 KIK47643.1 - 1.5e-34 117.9 0.0 1.8e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Sas10_Utp3 PF04000.15 KIK47644.1 - 7.6e-17 61.7 0.5 1.6e-16 60.7 0.0 1.8 2 0 0 2 2 2 1 Sas10/Utp3/C1D family FBPase PF00316.20 KIK47644.1 - 0.068 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain LRR_4 PF12799.7 KIK47645.1 - 4e-06 27.1 7.6 0.16 12.4 0.3 5.3 4 2 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KIK47645.1 - 5.4e-05 22.9 9.0 0.018 15.0 0.4 5.0 4 0 0 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.6 KIK47645.1 - 0.015 15.0 0.3 25 4.7 0.1 3.9 3 0 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 KIK47645.1 - 0.11 13.1 12.7 3 8.7 0.6 5.1 5 0 0 5 5 5 0 Leucine Rich Repeat YABBY PF04690.13 KIK47646.1 - 2.2e-09 38.1 0.2 2.5e-09 37.9 0.2 1.1 1 0 0 1 1 1 1 YABBY protein Ccdc124 PF06244.12 KIK47646.1 - 5.7e-05 23.7 2.4 7.4e-05 23.3 2.4 1.2 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_2 PF09011.10 KIK47646.1 - 0.00013 22.5 0.4 0.00017 22.1 0.4 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 KIK47646.1 - 0.00044 20.6 1.1 0.00066 20.0 1.1 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box Sec1 PF00995.23 KIK47648.1 - 3.9e-114 383.0 0.0 4.5e-114 382.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Peripla_BP_4 PF13407.6 KIK47648.1 - 0.15 11.6 0.1 1.4 8.4 0.1 2.2 2 0 0 2 2 2 0 Periplasmic binding protein domain cNMP_binding PF00027.29 KIK47649.1 - 2.1e-30 104.6 0.1 7.5e-15 54.8 0.0 5.8 6 0 0 6 6 6 5 Cyclic nucleotide-binding domain Patatin PF01734.22 KIK47649.1 - 4.3e-19 69.5 1.9 2.8e-13 50.5 1.0 3.0 2 0 0 2 2 2 2 Patatin-like phospholipase Homeodomain PF00046.29 KIK47650.1 - 1.8e-43 146.2 12.6 3.6e-17 61.9 0.4 3.4 3 0 0 3 3 3 3 Homeodomain Homeobox_KN PF05920.11 KIK47650.1 - 2.9e-14 52.7 2.3 3.9e-05 23.5 0.1 3.6 3 0 0 3 3 3 3 Homeobox KN domain YdaS_antitoxin PF15943.5 KIK47650.1 - 9.6e-08 31.8 0.2 0.05 13.5 0.0 3.3 3 0 0 3 3 3 2 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 KIK47650.1 - 9.4e-05 22.4 0.1 0.83 9.8 0.0 3.3 3 0 0 3 3 3 2 Helix-turn-helix HOCHOB PF17943.1 KIK47650.1 - 0.00014 22.6 0.0 0.42 11.3 0.0 3.2 3 0 0 3 3 3 1 Homeobox-cysteine loop-homeobox Homez PF11569.8 KIK47650.1 - 0.015 14.7 0.3 7.1 6.2 0.0 2.9 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez Phage_CI_repr PF07022.13 KIK47650.1 - 0.022 14.8 0.2 12 6.1 0.0 2.6 3 0 0 3 3 3 0 Bacteriophage CI repressor helix-turn-helix domain MarR PF01047.22 KIK47650.1 - 0.068 13.1 0.0 24 5.0 0.0 2.8 2 0 0 2 2 2 0 MarR family Terminase_5 PF06056.12 KIK47650.1 - 0.096 12.6 0.2 4.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) CRIC_ras_sig PF10534.9 KIK47650.1 - 0.12 12.6 0.9 9.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras HTH_24 PF13412.6 KIK47650.1 - 0.34 10.5 0.8 18 5.0 0.0 3.4 4 0 0 4 4 4 0 Winged helix-turn-helix DNA-binding HTH_32 PF13565.6 KIK47650.1 - 3.4 8.4 9.1 4.1 8.1 0.2 3.6 3 0 0 3 3 3 0 Homeodomain-like domain Fumble PF03630.14 KIK47651.1 - 6.7e-126 419.9 0.0 1.3e-125 419.0 0.0 1.5 1 1 0 1 1 1 1 Fumble Adaptin_N PF01602.20 KIK47652.1 - 3.1e-118 395.6 0.0 4e-118 395.2 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KIK47652.1 - 5.6e-55 185.6 1.9 1.6e-54 184.2 1.9 1.8 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KIK47652.1 - 1e-34 119.1 0.0 2.3e-34 118.0 0.0 1.7 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KIK47652.1 - 1.4e-17 63.8 2.5 5.3e-10 39.6 0.0 5.8 3 2 3 6 6 6 4 HEAT repeats Cnd1 PF12717.7 KIK47652.1 - 3.2e-05 24.0 9.7 0.29 11.2 0.3 4.7 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KIK47652.1 - 0.001 19.1 3.7 13 6.3 0.1 6.2 6 0 0 6 6 6 1 HEAT repeat HEAT_PBS PF03130.16 KIK47652.1 - 0.021 15.4 2.3 31 5.6 0.0 5.4 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat CE2_N PF17996.1 KIK47654.1 - 9.6e-05 22.3 0.3 0.013 15.5 0.0 2.5 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal Aerolysin PF01117.20 KIK47654.1 - 0.0052 16.0 0.3 0.0065 15.7 0.3 1.1 1 0 0 1 1 1 1 Aerolysin toxin Methyltransf_25 PF13649.6 KIK47655.1 - 4.1e-08 33.8 0.0 1.5e-07 32.0 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK47655.1 - 4.1e-08 33.2 0.0 5.6e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK47655.1 - 6.9e-07 29.9 0.0 1.9e-06 28.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK47655.1 - 3.8e-05 23.5 0.0 0.00032 20.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KIK47655.1 - 0.00026 21.2 0.0 0.00039 20.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 KIK47655.1 - 0.00057 20.5 0.0 0.0012 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KIK47655.1 - 0.0012 18.4 0.0 0.0045 16.5 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 KIK47655.1 - 0.028 13.8 0.0 0.14 11.5 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KIK47655.1 - 0.053 12.8 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 KIK47655.1 - 0.067 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Ist1 PF03398.14 KIK47656.1 - 3.9e-62 209.0 0.3 4.9e-62 208.7 0.3 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Indigoidine_A PF04227.12 KIK47656.1 - 0.027 13.8 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Indigoidine synthase A like protein SH3_1 PF00018.28 KIK47657.1 - 6.3e-13 48.1 0.0 1.2e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KIK47657.1 - 6.2e-10 38.6 0.0 1.1e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KIK47657.1 - 6.1e-09 35.6 0.0 9.8e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain La_HTH_kDCL PF18177.1 KIK47657.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain Ras PF00071.22 KIK47658.1 - 1.1e-58 197.4 0.1 1.3e-58 197.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK47658.1 - 9.3e-37 125.9 0.0 1.2e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK47658.1 - 1.6e-13 50.5 0.1 1.8e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIK47658.1 - 2.4e-06 27.6 0.0 4.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK47658.1 - 1.1e-05 25.4 0.3 0.091 12.7 0.0 2.4 1 1 2 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 KIK47658.1 - 1.8e-05 24.4 0.0 3.6e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KIK47658.1 - 3e-05 23.5 0.0 3.6e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KIK47658.1 - 0.0059 17.0 0.2 0.013 15.9 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 KIK47658.1 - 0.041 13.2 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Septin TniB PF05621.11 KIK47658.1 - 0.17 11.3 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein RRM_1 PF00076.22 KIK47659.1 - 5.8e-16 58.1 0.3 1.6e-11 43.9 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Extensin_2 PF04554.13 KIK47659.1 - 1.3e-05 25.2 22.1 1.3e-05 25.2 22.1 4.5 5 0 0 5 5 5 1 Extensin-like region DUF4523 PF15023.6 KIK47659.1 - 0.038 13.8 0.0 2.3 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) PUF PF00806.19 KIK47660.1 - 0.073 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat Nramp PF01566.18 KIK47661.1 - 4.7e-85 285.7 27.6 1.1e-48 166.1 8.2 2.3 3 0 0 3 3 3 2 Natural resistance-associated macrophage protein RNase_H PF00075.24 KIK47662.1 - 4.8e-33 114.4 0.0 8.9e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 RNase H Lipase_3 PF01764.25 KIK47663.1 - 6.7e-08 32.5 0.0 2.8e-06 27.3 0.0 2.3 1 1 1 2 2 2 2 Lipase (class 3) Abhydrolase_6 PF12697.7 KIK47663.1 - 0.016 15.8 0.0 0.032 14.8 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family WD40 PF00400.32 KIK47664.1 - 1.8e-27 95.0 13.2 0.00098 19.9 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK47664.1 - 1.8e-13 50.6 1.5 0.00025 21.3 0.3 5.0 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK47664.1 - 4.2e-05 23.5 0.0 9.4e-05 22.4 0.1 1.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIK47664.1 - 0.0046 16.3 0.0 1 8.6 0.0 2.5 2 1 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 KIK47664.1 - 0.008 15.2 1.4 5 6.0 0.0 3.6 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 KIK47664.1 - 0.0085 15.9 1.0 0.034 13.9 0.4 2.0 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 KIK47664.1 - 0.043 12.5 0.8 3.8 6.0 0.0 2.9 2 1 0 3 3 3 0 Nucleoporin Nup120/160 Pkinase_Tyr PF07714.17 KIK47665.1 - 1.3e-28 100.1 0.0 1.4e-28 99.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK47665.1 - 4.7e-27 95.0 0.0 5.5e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KIK47665.1 - 5.3e-09 35.8 0.0 6.9e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK47665.1 - 0.036 13.4 0.0 0.05 13.0 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KIK47666.1 - 8.7e-29 100.6 0.0 9.3e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK47666.1 - 2e-24 86.4 0.0 2.5e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK47666.1 - 0.00091 18.6 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK47666.1 - 0.002 17.0 0.0 0.0024 16.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KIK47666.1 - 0.005 16.5 0.0 0.0078 15.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIK47666.1 - 0.011 15.7 0.1 0.018 15.0 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK47666.1 - 0.023 14.0 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 KIK47666.1 - 0.24 10.4 0.1 0.35 9.9 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 WD40 PF00400.32 KIK47667.1 - 1.6e-24 85.7 12.8 1.2e-05 26.0 0.0 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK47667.1 - 5.7e-11 42.6 1.7 0.8 10.0 0.1 6.3 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK47667.1 - 1.1e-09 37.7 1.4 0.04 12.9 0.1 4.2 2 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KIK47667.1 - 0.0017 17.2 0.0 0.24 10.1 0.0 2.2 2 0 0 2 2 2 2 Nup133 N terminal like WD40_like PF17005.5 KIK47667.1 - 0.0091 15.4 0.0 3.5 6.9 0.0 3.0 2 2 1 3 3 3 2 WD40-like domain ISP3_C PF18045.1 KIK47667.1 - 0.1 12.5 0.0 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 ISP3 C-terminal Pkinase_Tyr PF07714.17 KIK47668.1 - 1.1e-21 77.3 0.0 1.4e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK47668.1 - 9.8e-20 71.0 0.0 1.2e-19 70.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KIK47668.1 - 2.3e-06 27.1 0.0 2.8e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like DUF4096 PF13340.6 KIK47668.1 - 0.15 12.3 0.1 4.2 7.7 0.0 2.7 3 0 0 3 3 3 0 Putative transposase of IS4/5 family (DUF4096) Pkinase_Tyr PF07714.17 KIK47669.1 - 1.3e-30 106.6 0.0 1.6e-30 106.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK47669.1 - 1.8e-26 93.1 0.0 2.3e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIK47669.1 - 0.0082 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIK47669.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Myb_DNA-bind_2 PF08914.11 KIK47670.1 - 1.7e-13 50.5 6.0 1.7e-11 44.1 5.7 2.2 1 1 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.10 KIK47670.1 - 0.028 15.0 9.1 1.2 9.7 9.1 2.3 1 1 0 1 1 1 0 Rap1, DNA-binding F-box-like PF12937.7 KIK47671.1 - 5.1e-05 23.1 0.4 0.0002 21.2 0.4 2.1 1 1 0 1 1 1 1 F-box-like Glycos_transf_1 PF00534.20 KIK47672.1 - 1.8e-22 79.7 0.0 4e-22 78.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIK47672.1 - 1.2e-19 71.0 2.5 1.4e-19 70.8 1.6 1.6 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KIK47672.1 - 1.9e-10 41.3 0.0 3.7e-09 37.1 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIK47672.1 - 5.2e-08 33.5 0.4 1.9e-07 31.7 0.2 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KIK47672.1 - 0.0039 17.6 0.0 0.0076 16.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF2607 PF10795.9 KIK47672.1 - 0.0096 16.0 0.4 0.027 14.6 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2607) Pkinase_fungal PF17667.1 KIK47675.1 - 1.7e-43 149.0 0.0 6.1e-28 97.7 0.0 2.0 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 KIK47675.1 - 5.5e-07 29.7 0.2 1.3e-06 28.5 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIK47675.1 - 0.00016 21.3 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KIK47675.1 - 0.00068 19.1 0.1 0.0041 16.5 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIK47675.1 - 0.17 11.2 0.2 1 8.7 0.2 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1670 PF07900.11 KIK47676.1 - 0.038 13.3 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1670) CLN3 PF02487.17 KIK47678.1 - 0.029 13.4 0.1 0.034 13.2 0.1 1.0 1 0 0 1 1 1 0 CLN3 protein MtrD PF04207.12 KIK47678.1 - 0.04 13.6 0.1 0.046 13.4 0.1 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D KDZ PF18758.1 KIK47679.1 - 1.1e-36 126.5 0.0 5.3e-36 124.3 0.0 2.0 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Peptidase_C48 PF02902.19 KIK47679.1 - 1e-11 45.1 1.1 2e-11 44.2 1.1 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CxC1 PF18802.1 KIK47679.1 - 3.2e-06 27.2 0.5 7.5e-06 26.0 0.5 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases W2 PF02020.18 KIK47679.1 - 0.085 13.0 1.0 1.5 9.1 0.2 2.8 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon DOPA_dioxygen PF08883.11 KIK47683.1 - 1.6e-30 105.4 0.0 2.1e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family AA_kinase PF00696.28 KIK47684.1 - 1.5e-39 136.1 1.9 2e-39 135.6 1.9 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KIK47684.1 - 3.2e-11 43.0 1.0 1.4e-05 25.0 0.1 2.8 3 0 0 3 3 3 2 PUA domain Pribosyltran_N PF13793.6 KIK47685.1 - 2.7e-48 162.7 0.2 1.1e-47 160.7 0.0 2.1 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KIK47685.1 - 6.6e-35 120.8 0.4 6.6e-31 107.8 0.2 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KIK47685.1 - 2.5e-16 59.6 0.0 3.7e-15 55.8 0.0 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KIK47685.1 - 2.4e-05 23.9 0.0 3.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KIK47685.1 - 0.008 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase Per1 PF04080.13 KIK47687.1 - 6.4e-101 337.4 14.5 7.7e-101 337.1 14.5 1.1 1 0 0 1 1 1 1 Per1-like family Hist_deacetyl PF00850.19 KIK47688.1 - 2.1e-81 273.7 0.1 2.7e-81 273.4 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Phos_pyr_kin PF08543.12 KIK47689.1 - 1.1e-83 280.4 0.2 1.3e-81 273.6 0.2 2.1 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KIK47689.1 - 9.1e-38 130.2 0.3 1.2e-37 129.8 0.3 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 KIK47689.1 - 1.1e-08 34.8 0.1 0.00036 19.9 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase GSAP-16 PF14959.6 KIK47689.1 - 0.22 11.5 0.2 0.53 10.2 0.2 1.6 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term RNA_polI_A34 PF08208.11 KIK47690.1 - 2.6e-24 86.5 0.5 2.6e-24 86.5 0.5 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase I subunit RPA34.5 Ada3 PF10198.9 KIK47691.1 - 1.4e-25 90.0 1.5 1.4e-25 90.0 1.5 2.6 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 Herpes_UL25 PF01499.16 KIK47691.1 - 0.046 12.2 0.3 0.082 11.4 0.3 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family MgtE PF01769.16 KIK47692.1 - 7.3e-38 129.7 10.7 6.5e-24 84.7 8.5 3.6 3 1 1 4 4 4 2 Divalent cation transporter Phage_holin_3_3 PF16083.5 KIK47692.1 - 0.0055 16.8 0.6 0.0055 16.8 0.6 3.9 4 1 1 5 5 5 1 LydA holin phage, holin superfamily III MgtE PF01769.16 KIK47693.1 - 8.8e-43 145.6 14.7 5.2e-23 81.8 11.1 3.6 3 1 1 4 4 4 2 Divalent cation transporter DUF5383 PF17355.2 KIK47693.1 - 0.024 15.0 0.2 4.9 7.5 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5383) Phage_holin_4_1 PF05105.12 KIK47694.1 - 0.055 13.6 0.4 0.055 13.6 0.4 2.0 2 0 0 2 2 2 0 Bacteriophage holin family Phage_holin_4_1 PF05105.12 KIK47695.1 - 0.03 14.5 0.4 0.03 14.5 0.4 2.2 1 1 0 2 2 2 0 Bacteriophage holin family HhH-GPD PF00730.25 KIK47696.1 - 4.9e-18 65.6 0.0 8.5e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KIK47696.1 - 1.1e-07 31.3 0.0 2.5e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KIK47696.1 - 0.014 16.0 0.5 1.2 9.8 0.0 2.6 1 1 2 3 3 3 0 Helix-hairpin-helix domain Mak10 PF04112.13 KIK47697.1 - 4.3e-50 169.5 0.0 1.1e-49 168.2 0.0 1.7 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase tRNA-synt_1b PF00579.25 KIK47698.1 - 2.6e-73 246.9 0.0 3.2e-73 246.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HMG_box PF00505.19 KIK47699.1 - 2.2e-10 40.8 8.2 3.4e-09 37.0 8.2 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK47699.1 - 2.5e-05 24.8 4.0 3.8e-05 24.2 4.0 1.3 1 1 0 1 1 1 1 HMG-box domain Protamine_like PF06382.11 KIK47699.1 - 0.00066 19.9 0.3 0.0019 18.4 0.2 1.7 2 0 0 2 2 2 1 Protamine and protamine like COX4 PF02936.14 KIK47699.1 - 0.039 14.0 0.6 0.044 13.8 0.6 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Mit_KHE1 PF10173.9 KIK47699.1 - 0.086 12.9 0.3 0.097 12.7 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF1691 PF07950.11 KIK47700.1 - 1.1e-06 29.3 1.3 4.5e-06 27.4 0.4 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1691) VMA21 PF09446.10 KIK47700.1 - 0.0024 17.9 4.0 0.013 15.6 0.4 3.0 3 1 0 3 3 3 1 VMA21-like domain Cerato-platanin PF07249.12 KIK47701.1 - 9.8e-45 151.5 1.2 1.1e-44 151.3 1.2 1.0 1 0 0 1 1 1 1 Cerato-platanin RNase_PH PF01138.21 KIK47702.1 - 4.1e-15 56.4 0.0 8.2e-15 55.5 0.0 1.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 TFB6 PF17110.5 KIK47703.1 - 7e-05 22.6 0.1 0.0004 20.2 0.1 2.1 1 1 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH MRP-S33 PF08293.11 KIK47704.1 - 2e-28 98.4 0.1 2.4e-28 98.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 SUV3_C PF12513.8 KIK47705.1 - 1.7e-15 56.7 1.8 3.9e-15 55.5 1.8 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KIK47705.1 - 3.9e-09 36.8 0.0 9.3e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain p450 PF00067.22 KIK47706.1 - 2.2e-06 26.7 0.2 7.2e-06 25.0 0.2 1.7 1 1 0 1 1 1 1 Cytochrome P450 DUF3302 PF11742.8 KIK47707.1 - 0.036 14.2 1.5 0.044 13.9 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) adh_short_C2 PF13561.6 KIK47711.1 - 4.2e-50 170.5 0.3 5.9e-50 170.0 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK47711.1 - 4.8e-43 146.9 0.4 8.3e-43 146.1 0.4 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK47711.1 - 8.2e-09 35.6 0.1 1.2e-08 35.1 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1598 PF07643.11 KIK47711.1 - 0.0021 18.3 0.0 0.01 16.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1598) F420_oxidored PF03807.17 KIK47711.1 - 0.0026 18.3 0.3 0.0055 17.3 0.3 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 KIK47711.1 - 0.0062 16.0 0.1 0.17 11.4 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KIK47711.1 - 0.0075 15.6 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 KIK47711.1 - 0.032 13.6 0.1 0.052 12.9 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KIK47711.1 - 0.037 14.1 0.1 0.064 13.3 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KIK47711.1 - 0.078 13.4 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 KIK47711.1 - 0.088 12.7 0.2 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KIK47711.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_tranf_2_3 PF13641.6 KIK47711.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 AdoHcyase_NAD PF00670.21 KIK47711.1 - 0.16 12.0 0.2 0.31 11.1 0.2 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain VWA_2 PF13519.6 KIK47712.1 - 1.1e-08 35.7 0.0 2.5e-08 34.5 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KIK47712.1 - 3.1e-05 23.5 0.1 4.7e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA PF00092.28 KIK47712.1 - 7.5e-05 23.0 0.0 0.00011 22.6 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KIK47712.1 - 0.00026 21.0 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain RHD3 PF05879.12 KIK47713.1 - 6.7e-06 24.6 0.2 1.1e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KIK47713.1 - 0.00051 19.4 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Asp PF00026.23 KIK47714.1 - 2.8e-83 280.0 2.8 3.2e-83 279.7 2.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK47714.1 - 6.1e-12 46.1 3.0 8.3e-06 26.2 0.7 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK47714.1 - 0.00091 19.8 0.1 3.1 8.5 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KIK47714.1 - 0.0039 17.0 0.0 0.0088 15.8 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.23 KIK47715.1 - 8.7e-76 255.3 0.8 1e-75 255.1 0.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK47715.1 - 7.5e-07 29.6 1.6 0.027 14.7 0.0 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KIK47715.1 - 0.00091 19.0 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Glyoxalase_3 PF13468.6 KIK47716.1 - 2.3e-31 109.3 0.0 5.4e-31 108.1 0.0 1.6 1 1 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KIK47716.1 - 0.0053 17.0 0.0 2.4 8.5 0.0 2.8 2 1 0 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ABC2_membrane PF01061.24 KIK47717.1 - 1.3e-36 126.0 18.1 1.3e-36 126.0 18.1 2.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KIK47717.1 - 4.9e-22 78.9 0.0 1e-21 77.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KIK47717.1 - 0.0057 16.6 0.4 0.011 15.7 0.4 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KIK47717.1 - 0.012 16.0 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC2_membrane_3 PF12698.7 KIK47717.1 - 0.014 14.6 26.3 0.033 13.3 26.1 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_22 PF13401.6 KIK47717.1 - 0.017 15.4 0.0 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KIK47717.1 - 0.035 14.0 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_21 PF13304.6 KIK47717.1 - 0.039 13.8 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIK47717.1 - 0.046 14.2 0.2 0.071 13.6 0.2 1.2 1 0 0 1 1 1 0 AAA domain EGF PF00008.27 KIK47717.1 - 0.047 14.0 6.0 0.2 12.0 1.3 3.1 2 0 0 2 2 2 0 EGF-like domain AAA_29 PF13555.6 KIK47717.1 - 0.053 13.3 0.6 0.15 11.8 0.6 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KIK47717.1 - 0.12 12.1 0.6 0.51 10.0 0.2 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KIK47717.1 - 0.19 10.9 0.2 0.38 9.9 0.2 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 KIK47717.1 - 0.23 11.9 0.8 0.39 11.1 0.3 1.6 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) COX17 PF05051.13 KIK47718.1 - 2.7e-23 82.0 3.5 3.3e-23 81.8 3.5 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cerato-platanin PF07249.12 KIK47719.1 - 1.5e-42 144.5 2.3 1.8e-42 144.2 2.3 1.1 1 0 0 1 1 1 1 Cerato-platanin Zn_clus PF00172.18 KIK47720.1 - 0.023 14.8 7.3 0.79 9.9 1.3 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_25 PF13649.6 KIK47721.1 - 2.4e-17 63.4 0.0 5.3e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK47721.1 - 2.3e-15 57.0 0.0 4.1e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK47721.1 - 1.9e-14 53.9 0.0 2.5e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK47721.1 - 4.5e-14 52.5 0.0 6.3e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK47721.1 - 6.7e-12 46.0 0.0 1.2e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK47721.1 - 9.5e-07 28.4 0.0 2e-06 27.3 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KIK47721.1 - 3.2e-05 23.5 0.0 4.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 KIK47721.1 - 0.00055 19.0 0.0 0.00069 18.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 KIK47721.1 - 0.0016 17.9 0.0 0.0021 17.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 KIK47721.1 - 0.025 14.5 0.0 0.049 13.5 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_32 PF13679.6 KIK47721.1 - 0.054 13.5 0.0 0.083 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.11 KIK47721.1 - 0.055 13.1 0.0 0.078 12.6 0.0 1.4 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CheR PF01739.18 KIK47721.1 - 0.17 11.3 0.0 0.74 9.3 0.0 1.9 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain IMS PF00817.20 KIK47722.1 - 1.3e-41 142.1 0.0 2.5e-39 134.7 0.0 2.7 2 0 0 2 2 2 1 impB/mucB/samB family REV1_C PF16727.5 KIK47722.1 - 2.9e-26 91.7 2.2 2.9e-26 91.7 2.2 1.8 2 0 0 2 2 2 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 KIK47722.1 - 6.5e-14 52.6 0.0 1.6e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 KIK47722.1 - 2.8e-10 40.5 0.0 6.1e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KIK47722.1 - 1.6e-06 28.4 0.0 3.4e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KIK47722.1 - 1.5e-05 24.8 0.1 3.2e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.8 KIK47722.1 - 0.00074 19.7 0.0 0.0022 18.2 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif UBM PF14377.6 KIK47722.1 - 0.035 13.6 9.1 0.071 12.6 0.3 3.9 4 0 0 4 4 4 0 Ubiquitin binding region DUF1805 PF08827.11 KIK47722.1 - 0.14 12.5 0.0 0.44 10.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) PP2C PF00481.21 KIK47723.1 - 6e-22 78.5 0.0 1.9e-20 73.6 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KIK47723.1 - 7.9e-07 29.2 0.0 0.021 14.8 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KIK47723.1 - 1.1e-06 28.4 0.0 3.3e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C Furin-like_2 PF15913.5 KIK47724.1 - 7e-05 22.9 24.8 0.0011 19.0 1.5 7.2 1 1 3 6 6 6 3 Furin-like repeat, cysteine-rich EGF_2 PF07974.13 KIK47724.1 - 0.00013 22.3 12.5 0.00013 22.3 12.5 12.2 13 2 0 13 13 13 2 EGF-like domain GF_recep_IV PF14843.6 KIK47724.1 - 0.0021 17.9 31.2 0.0021 17.9 31.2 5.7 1 1 5 6 6 6 4 Growth factor receptor domain IV DUF4381 PF14316.6 KIK47724.1 - 0.3 11.3 3.6 0.51 10.6 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Calcipressin PF04847.12 KIK47725.1 - 3.8e-33 114.8 0.0 4.8e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Calcipressin Nup35_RRM_2 PF14605.6 KIK47725.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ccdc124 PF06244.12 KIK47726.1 - 1.8e-28 99.7 23.2 4.5e-28 98.4 20.3 2.7 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 DUF2852 PF11014.8 KIK47726.1 - 0.14 12.3 0.3 0.14 12.3 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2852) CDC45 PF02724.14 KIK47729.1 - 3.1e-227 755.9 0.0 3.7e-227 755.6 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein TetR_C_5 PF08360.11 KIK47729.1 - 0.069 13.3 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 QacR-like protein, C-terminal region GTP_EFTU PF00009.27 KIK47732.1 - 3.2e-34 118.2 2.2 1.1e-32 113.1 2.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KIK47732.1 - 5.8e-29 100.3 0.3 2.1e-28 98.5 0.3 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KIK47732.1 - 2.4e-07 30.8 0.2 6e-07 29.5 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KIK47732.1 - 4.3e-05 23.0 0.0 8.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family IF2_N PF04760.15 KIK47732.1 - 0.00012 21.9 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region SRPRB PF09439.10 KIK47732.1 - 0.0009 18.7 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KIK47732.1 - 0.00098 18.9 0.2 0.0071 16.1 0.2 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 KIK47732.1 - 0.0013 19.0 0.0 0.0025 18.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KIK47732.1 - 0.0022 17.6 0.0 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 Ras family GTP_EFTU_D4 PF14578.6 KIK47732.1 - 0.0089 15.9 10.4 0.16 11.9 0.1 4.1 4 0 0 4 4 4 2 Elongation factor Tu domain 4 AAA_26 PF13500.6 KIK47732.1 - 0.058 13.2 1.0 0.25 11.1 0.2 2.2 2 0 0 2 2 2 0 AAA domain CHORD PF04968.12 KIK47733.1 - 5.5e-50 167.9 12.1 5.5e-25 87.9 2.4 2.4 2 0 0 2 2 2 2 CHORD CS PF04969.16 KIK47733.1 - 5.3e-14 53.0 0.1 9.8e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 CS domain BTK PF00779.19 KIK47733.1 - 2 8.3 9.5 6.4 6.7 0.3 3.5 4 0 0 4 4 4 0 BTK motif Mito_carr PF00153.27 KIK47734.1 - 4.7e-08 32.9 0.1 0.029 14.3 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein 2OG-FeII_Oxy_2 PF13532.6 KIK47735.1 - 9e-10 39.1 0.0 1.2e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MHB PF16525.5 KIK47735.1 - 0.022 15.0 0.1 0.038 14.2 0.1 1.3 1 0 0 1 1 1 0 Haemophore, haem-binding WD40 PF00400.32 KIK47737.1 - 3.4e-40 135.3 18.7 2.1e-11 44.1 0.6 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK47737.1 - 1e-14 54.6 2.4 0.00033 20.9 0.0 5.2 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK47737.1 - 7.8e-08 31.7 1.4 0.073 12.0 0.0 4.5 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK47737.1 - 1.7e-06 27.0 2.4 0.28 9.8 0.0 4.0 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Hira PF07569.11 KIK47737.1 - 5.2e-06 26.3 0.6 0.013 15.2 0.1 3.1 1 1 2 4 4 4 3 TUP1-like enhancer of split Nucleoporin_N PF08801.11 KIK47737.1 - 0.00056 18.8 2.3 0.031 13.0 0.0 3.8 1 1 2 4 4 4 1 Nup133 N terminal like PALB2_WD40 PF16756.5 KIK47737.1 - 0.0052 15.8 0.1 0.0052 15.8 0.1 2.6 4 0 0 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 KIK47737.1 - 0.047 12.0 0.0 0.075 11.3 0.0 1.4 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz GATase_2 PF00310.21 KIK47739.1 - 3.9e-177 589.2 0.0 5.1e-177 588.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KIK47739.1 - 5.6e-155 516.0 0.0 9.7e-155 515.2 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KIK47739.1 - 1.8e-112 375.4 0.0 2.8e-111 371.5 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KIK47739.1 - 3e-87 291.1 3.7 4.9e-87 290.5 3.7 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KIK47739.1 - 2.4e-24 86.1 0.0 1.3e-23 83.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KIK47739.1 - 1.3e-21 76.5 0.1 2.6e-21 75.5 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox PF00070.27 KIK47739.1 - 2.3e-08 34.4 0.6 2.7e-05 24.7 0.0 4.0 4 1 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK47739.1 - 5.8e-08 32.7 0.2 0.0024 17.5 0.1 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK47739.1 - 7.2e-08 32.6 0.0 3.1e-07 30.5 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIK47739.1 - 3.5e-06 26.5 0.5 0.036 13.3 0.0 3.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK47739.1 - 1.9e-05 23.6 0.6 4.2e-05 22.4 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 KIK47739.1 - 0.00057 19.3 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FMN_dh PF01070.18 KIK47739.1 - 0.00092 18.3 0.7 0.0042 16.2 0.9 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase FAD_binding_2 PF00890.24 KIK47739.1 - 0.0038 16.4 0.0 0.0038 16.4 0.0 2.6 3 0 0 3 3 2 1 FAD binding domain NAD_binding_7 PF13241.6 KIK47739.1 - 0.01 16.3 0.5 1.9 9.0 0.1 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KIK47739.1 - 0.011 15.0 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KIK47739.1 - 0.013 14.8 0.8 0.022 14.1 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase FMO-like PF00743.19 KIK47739.1 - 0.019 13.4 0.1 5.2 5.4 0.0 2.7 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like AlaDh_PNT_C PF01262.21 KIK47739.1 - 0.027 13.8 0.0 1.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 KIK47739.1 - 0.035 14.2 0.2 13 5.8 0.0 2.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Thi4 PF01946.17 KIK47739.1 - 0.042 13.1 0.9 0.1 11.8 0.0 2.0 2 0 0 2 2 2 0 Thi4 family GATase_6 PF13522.6 KIK47739.1 - 0.055 13.7 0.2 0.31 11.2 0.1 2.2 2 0 0 2 2 2 0 Glutamine amidotransferase domain Lycopene_cycl PF05834.12 KIK47739.1 - 0.096 11.7 0.1 1.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KIK47739.1 - 0.19 11.1 0.3 0.61 9.4 0.0 2.0 2 0 0 2 2 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KIK47739.1 - 0.48 9.5 1.9 1.6 7.8 0.1 2.3 2 1 0 2 2 2 0 Glucose inhibited division protein A Acetyltransf_13 PF13880.6 KIK47741.1 - 1.1e-14 54.1 0.0 2.2e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KIK47741.1 - 1.5e-09 37.5 0.1 2.4e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 KIK47741.1 - 0.0019 18.6 0.0 0.012 16.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIK47741.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK47741.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF2476 PF10630.9 KIK47741.1 - 0.11 12.6 2.4 6.6 6.8 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2476) Acetyltransf_CG PF14542.6 KIK47741.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DPBB_1 PF03330.18 KIK47742.1 - 0.00021 21.5 0.0 0.00042 20.5 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase Pectate_lyase_3 PF12708.7 KIK47743.1 - 5.5e-92 307.5 21.5 2.6e-81 272.5 9.0 3.0 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KIK47743.1 - 1.3e-09 37.6 3.5 9.9e-05 22.0 0.1 3.1 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Cellulase PF00150.18 KIK47748.1 - 8.6e-11 41.8 0.0 1.8e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PRIMA1 PF16101.5 KIK47748.1 - 0.015 15.3 0.0 0.046 13.8 0.0 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Orf78 PF06024.12 KIK47748.1 - 0.2 12.0 0.0 0.42 10.9 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) ODV-E18 PF10717.9 KIK47748.1 - 8 6.4 9.8 0.35 10.8 2.2 2.6 2 1 1 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 COA2 PF17051.5 KIK47750.1 - 0.055 13.5 0.9 8.9 6.4 0.1 3.1 3 0 0 3 3 3 0 Cytochrome C oxidase assembly factor 2 Histone PF00125.24 KIK47752.1 - 9.9e-50 168.3 3.5 1.1e-49 168.1 3.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KIK47752.1 - 3.9e-05 23.7 0.1 7.1e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KIK47752.1 - 7.1e-05 23.1 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 KIK47752.1 - 0.00081 20.0 1.5 0.001 19.7 1.5 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KIK47752.1 - 0.005 17.1 0.0 0.0099 16.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone WD40 PF00400.32 KIK47753.1 - 3.9e-43 144.6 18.1 1.9e-07 31.7 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK47753.1 - 3.3e-23 81.8 0.0 8.6e-06 26.0 0.1 6.3 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK47753.1 - 5.3e-10 39.5 0.8 5.5e-05 23.1 0.0 3.5 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK47753.1 - 3.8e-08 32.7 0.2 0.071 12.1 0.0 4.0 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KIK47753.1 - 0.00046 19.0 0.1 0.076 11.7 0.0 3.1 1 1 2 3 3 3 1 Nup133 N terminal like IKI3 PF04762.12 KIK47753.1 - 0.0033 15.5 0.0 0.0053 14.8 0.0 1.2 1 0 0 1 1 1 1 IKI3 family Coatomer_WDAD PF04053.14 KIK47753.1 - 0.016 14.3 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Nbas_N PF15492.6 KIK47753.1 - 0.048 13.0 0.2 8.8 5.6 0.0 3.3 2 2 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Det1 PF09737.9 KIK47753.1 - 0.24 10.4 0.0 0.38 9.8 0.0 1.2 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 CBM_21 PF03370.13 KIK47754.1 - 5.6e-29 100.6 0.1 9.2e-29 99.9 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KIK47754.1 - 2e-08 34.7 0.9 3.9e-08 33.8 0.9 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) ArfGap PF01412.18 KIK47755.1 - 0.022 14.8 0.1 0.033 14.3 0.1 1.5 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf DUF5081 PF16887.5 KIK47756.1 - 0.22 10.6 0.0 0.28 10.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5081) ADK PF00406.22 KIK47758.1 - 7e-60 201.5 0.0 8.6e-60 201.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KIK47758.1 - 1.4e-21 77.3 0.2 3.6e-21 76.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KIK47758.1 - 7.6e-17 61.0 0.0 1.5e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KIK47758.1 - 0.0012 19.4 0.0 0.0025 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIK47758.1 - 0.0024 18.1 0.0 0.0056 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KIK47758.1 - 0.0073 15.6 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin C_Hendra PF16821.5 KIK47758.1 - 0.064 13.1 0.2 0.13 12.1 0.0 1.5 2 0 0 2 2 2 0 C protein from hendra and measles viruses DDOST_48kD PF03345.14 KIK47759.1 - 4.9e-130 434.1 0.0 5.9e-130 433.8 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta SNARE_assoc PF09335.11 KIK47760.1 - 1.1e-11 45.3 16.9 2.3e-11 44.2 11.8 3.0 2 1 1 3 3 3 1 SNARE associated Golgi protein Fun_ATP-synt_8 PF05933.13 KIK47760.1 - 0.023 14.9 0.9 0.023 14.9 0.9 2.9 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) S1FA PF04689.13 KIK47760.1 - 0.18 11.9 1.3 0.44 10.7 0.0 2.2 2 0 0 2 2 2 0 DNA binding protein S1FA Saf_2TM PF18303.1 KIK47760.1 - 6.1 6.4 10.1 0.99 9.0 0.2 3.0 2 1 0 2 2 2 0 SAVED-fused 2TM effector domain MF_alpha_N PF05436.11 KIK47762.1 - 0.12 12.3 0.1 0.14 12.1 0.1 1.1 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus RasGEF PF00617.19 KIK47764.1 - 0.00044 20.5 0.0 0.0011 19.2 0.0 1.7 1 1 1 2 2 2 1 RasGEF domain DEAD PF00270.29 KIK47765.1 - 1.2e-47 162.0 0.1 3.8e-47 160.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK47765.1 - 2.7e-29 101.8 0.2 5.3e-27 94.4 0.1 2.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Nha1_C PF08619.10 KIK47765.1 - 0.0022 17.3 15.3 0.0022 17.3 15.3 2.2 2 0 0 2 2 2 1 Alkali metal cation/H+ antiporter Nha1 C terminus DUF4530 PF15039.6 KIK47765.1 - 0.35 11.0 0.1 0.35 11.0 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) ANAPC4 PF12896.7 KIK47766.1 - 5e-38 130.7 0.1 1e-37 129.7 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KIK47766.1 - 1.2e-06 28.8 0.1 4.3e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain bZIP_1 PF00170.21 KIK47767.1 - 5.1e-05 23.3 2.6 0.00012 22.2 2.3 1.7 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIK47767.1 - 0.032 14.3 1.2 0.032 14.3 1.2 2.9 2 1 1 3 3 3 0 Basic region leucine zipper TolA_bind_tri PF16331.5 KIK47767.1 - 0.052 13.6 0.3 0.12 12.5 0.3 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation Lzipper-MIP1 PF14389.6 KIK47767.1 - 0.065 13.5 1.3 1.7 9.0 0.2 2.4 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Cep57_CLD_2 PF14197.6 KIK47767.1 - 0.16 12.1 1.5 0.33 11.1 1.5 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 bZIP_Maf PF03131.17 KIK47767.1 - 3.5 8.2 8.4 0.82 10.2 3.9 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor GPI2 PF06432.11 KIK47768.1 - 2.8e-86 289.4 15.2 3.2e-86 289.3 15.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase SVIP PF15811.5 KIK47769.1 - 0.00014 22.3 1.8 0.0002 21.8 1.8 1.3 1 0 0 1 1 1 1 Small VCP/p97-interacting protein Actin PF00022.19 KIK47771.1 - 2.6e-129 431.4 0.0 1.2e-128 429.3 0.0 1.7 1 1 0 1 1 1 1 Actin Ribosomal_S24e PF01282.19 KIK47772.1 - 4.9e-33 112.9 0.7 6.5e-33 112.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S24e DUF4870 PF09685.10 KIK47773.1 - 0.014 15.5 0.6 0.022 14.9 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) DUF1843 PF08898.10 KIK47774.1 - 0.14 12.7 0.1 0.33 11.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) ETS_PEA3_N PF04621.13 KIK47774.1 - 0.28 11.0 2.3 0.37 10.6 2.3 1.1 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain HEAT PF02985.22 KIK47775.1 - 5.5e-43 141.3 11.5 0.0031 17.6 0.0 13.7 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.6 KIK47775.1 - 8.2e-34 115.9 13.4 2.1e-10 40.8 0.0 8.0 3 3 5 8 8 8 7 HEAT repeats Vac14_Fab1_bd PF12755.7 KIK47775.1 - 1.8e-12 47.7 0.4 0.0079 16.8 0.0 7.2 3 3 6 9 9 9 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KIK47775.1 - 8.5e-10 38.9 12.0 0.077 13.5 0.0 9.5 8 3 3 11 11 11 2 HEAT-like repeat Cnd1 PF12717.7 KIK47775.1 - 1.8e-09 37.8 1.0 0.011 15.7 0.0 5.1 3 2 3 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KIK47775.1 - 3.1e-08 32.6 1.5 0.00047 18.8 0.3 3.7 2 2 0 2 2 2 1 Adaptin N terminal region Arm PF00514.23 KIK47775.1 - 8.2e-07 28.9 1.7 2.3 8.4 0.1 6.2 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat TAF6_C PF07571.13 KIK47775.1 - 2.9e-06 27.5 0.0 0.021 15.1 0.0 4.9 5 0 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain Ecm29 PF13001.7 KIK47775.1 - 0.0027 16.5 2.7 2.2 6.9 0.0 4.2 4 1 1 5 5 5 1 Proteasome stabiliser Peripla_BP_2 PF01497.18 KIK47775.1 - 0.024 14.2 0.0 0.098 12.2 0.0 1.9 2 0 0 2 2 2 0 Periplasmic binding protein Cohesin_HEAT PF12765.7 KIK47775.1 - 0.039 14.3 0.5 13 6.2 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion IFRD PF05004.13 KIK47775.1 - 0.069 12.3 0.4 3 6.9 0.1 3.5 3 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) HEAT_PBS PF03130.16 KIK47775.1 - 0.3 11.9 9.0 4.5 8.2 0.1 6.0 7 0 0 7 7 4 0 PBS lyase HEAT-like repeat Aldose_epim PF01263.20 KIK47776.1 - 8.2e-25 87.7 0.0 1e-24 87.4 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DNA_pol_B PF00136.21 KIK47777.1 - 1.2e-103 347.4 0.0 2e-103 346.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KIK47777.1 - 1.5e-25 90.1 0.0 7e-13 48.4 0.1 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KIK47777.1 - 1.6e-13 50.9 2.1 3.5e-13 49.8 2.1 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KIK47777.1 - 0.13 11.1 0.1 0.2 10.5 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral INCENP_ARK-bind PF03941.15 KIK47778.1 - 1.7e-19 69.5 2.4 1.7e-19 69.5 2.4 2.0 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region DCP2 PF05026.13 KIK47779.1 - 1.6e-32 111.7 2.1 2.8e-32 110.9 2.1 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KIK47779.1 - 1.6e-15 57.3 0.0 3.8e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Peptidase_C48 PF02902.19 KIK47780.1 - 7.6e-07 29.2 0.3 2.6e-06 27.5 0.3 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF3419 PF11899.8 KIK47780.1 - 0.045 12.9 0.1 0.065 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Dimer_Tnp_hAT PF05699.14 KIK47782.1 - 6.1e-15 54.8 0.1 1.6e-14 53.4 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Mur_ligase_M PF08245.12 KIK47782.1 - 0.11 12.5 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Mur ligase middle domain DUF5530 PF17670.1 KIK47782.1 - 0.44 10.3 2.3 4.4 7.1 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5530) DUF4937 PF16291.5 KIK47782.1 - 0.48 10.7 4.6 4.3 7.7 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4937 KDZ PF18758.1 KIK47784.1 - 1.2e-61 208.1 0.1 1.9e-61 207.5 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIK47784.1 - 1.6e-44 150.5 2.6 2.9e-44 149.6 0.5 2.6 3 0 0 3 3 3 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIK47784.1 - 3e-05 24.1 1.9 6e-05 23.1 0.1 2.4 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIK47785.1 - 2.7e-51 174.3 0.0 4.7e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Peptidase_C48 PF02902.19 KIK47785.1 - 6.5e-11 42.5 0.0 1.3e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CxC1 PF18802.1 KIK47785.1 - 0.0012 19.0 0.1 0.0056 16.8 0.0 2.1 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases Pribosyltran_N PF13793.6 KIK47791.1 - 7.1e-44 148.5 0.9 2.8e-43 146.5 0.1 2.1 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KIK47791.1 - 3e-39 135.0 4.4 6.4e-33 114.3 0.6 2.7 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KIK47791.1 - 3.7e-16 59.1 2.7 5.8e-15 55.2 0.5 2.6 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KIK47791.1 - 0.00076 19.0 0.2 0.0014 18.2 0.2 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pkinase PF00069.25 KIK47792.1 - 6.9e-53 179.7 0.0 2e-51 174.9 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK47792.1 - 9.6e-23 80.8 0.0 2.2e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CHCC PF10276.9 KIK47793.1 - 1.8e-17 63.1 2.0 2.5e-17 62.6 2.0 1.2 1 0 0 1 1 1 1 Zinc-finger domain AAA_2 PF07724.14 KIK47794.1 - 2.5e-48 164.4 0.0 4.9e-45 153.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KIK47794.1 - 3.3e-32 110.5 1.1 3.3e-32 110.5 1.1 2.9 2 1 1 3 3 2 1 AAA lid domain AAA PF00004.29 KIK47794.1 - 1.8e-23 83.4 0.0 6e-12 46.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KIK47794.1 - 7.3e-22 77.2 1.1 2.1e-21 75.8 0.1 2.4 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 KIK47794.1 - 5.4e-16 58.5 10.7 6.2e-13 48.7 0.3 4.1 4 0 0 4 4 3 1 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 KIK47794.1 - 1.9e-13 50.6 0.1 3.6e-07 30.3 0.0 3.4 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIK47794.1 - 5.9e-10 39.8 7.7 2.5e-06 28.0 0.0 4.8 4 2 1 5 5 3 2 AAA ATPase domain AAA_22 PF13401.6 KIK47794.1 - 4.4e-09 36.7 0.2 0.0052 17.1 0.0 4.1 3 3 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 KIK47794.1 - 6.3e-08 32.5 0.0 5.8e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 KIK47794.1 - 2.5e-06 27.3 0.0 0.0032 17.2 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 KIK47794.1 - 4.9e-06 26.4 0.0 0.018 14.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 KIK47794.1 - 2.2e-05 24.0 0.0 0.31 10.4 0.0 3.5 2 1 0 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 KIK47794.1 - 2.5e-05 23.7 0.0 0.014 14.8 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KIK47794.1 - 0.0002 21.7 0.0 1.3 9.4 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_18 PF13238.6 KIK47794.1 - 0.00023 21.7 0.0 0.28 11.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIK47794.1 - 0.00027 21.1 0.0 0.36 11.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KIK47794.1 - 0.00028 20.5 0.0 0.77 9.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region TIP49 PF06068.13 KIK47794.1 - 0.00029 20.2 0.0 0.24 10.6 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain RuvB_N PF05496.12 KIK47794.1 - 0.00039 20.2 0.1 2.5 7.8 0.0 3.8 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 KIK47794.1 - 0.0008 18.7 0.0 0.095 12.0 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 KIK47794.1 - 0.0026 17.7 0.0 0.24 11.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 KIK47794.1 - 0.0031 17.5 0.6 3.4 7.5 0.1 3.8 2 2 0 3 3 3 1 ATPase domain predominantly from Archaea Roc PF08477.13 KIK47794.1 - 0.0033 17.7 0.0 0.53 10.5 0.0 3.2 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 KIK47794.1 - 0.0046 17.2 1.5 2 8.6 0.0 3.4 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 KIK47794.1 - 0.0055 16.7 0.0 5.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KIK47794.1 - 0.0097 15.6 0.0 5.5 6.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KIK47794.1 - 0.01 15.9 0.0 0.92 9.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.27 KIK47794.1 - 0.011 16.2 0.6 3 8.4 0.0 3.2 3 0 0 3 3 3 0 ABC transporter Torsin PF06309.11 KIK47794.1 - 0.018 15.1 0.0 0.3 11.2 0.0 2.5 2 0 0 2 2 2 0 Torsin AAA_19 PF13245.6 KIK47794.1 - 0.022 15.1 0.0 9.2 6.6 0.0 3.5 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 KIK47794.1 - 0.034 14.1 0.0 4.6 7.1 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase Sigma54_activ_2 PF14532.6 KIK47794.1 - 0.038 14.1 0.0 7.8 6.6 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 KIK47794.1 - 0.039 13.4 0.0 2.4 7.6 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein DUF5368 PF17336.2 KIK47794.1 - 0.043 14.0 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5368) AAA_3 PF07726.11 KIK47794.1 - 0.046 13.6 0.0 41 4.0 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Spc7 PF08317.11 KIK47794.1 - 0.076 11.9 7.8 0.14 11.1 7.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein NTPase_1 PF03266.15 KIK47794.1 - 0.089 12.7 0.1 5.8 6.8 0.0 3.2 3 0 0 3 3 3 0 NTPase ResIII PF04851.15 KIK47794.1 - 0.1 12.6 0.0 7.3 6.6 0.0 3.0 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 KIK47794.1 - 0.23 11.0 4.3 13 5.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain BRE1 PF08647.11 KIK47794.1 - 0.25 11.5 5.4 0.76 9.9 5.4 1.9 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF4407 PF14362.6 KIK47794.1 - 0.31 10.4 6.3 0.58 9.5 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) 5_nucleotid PF05761.14 KIK47794.1 - 1.1 8.1 3.1 1.8 7.3 3.1 1.2 1 0 0 1 1 1 0 5' nucleotidase family AAA_23 PF13476.6 KIK47794.1 - 2.8 8.4 13.1 42 4.6 0.0 3.9 3 1 0 3 3 3 0 AAA domain WD40 PF00400.32 KIK47795.1 - 0.036 14.9 13.1 0.28 12.1 0.0 4.9 5 0 0 5 5 5 0 WD domain, G-beta repeat TMEM135_C_rich PF15982.5 KIK47796.1 - 5.5e-05 23.8 0.2 0.00034 21.2 0.1 2.1 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 HSCB_C PF07743.13 KIK47798.1 - 3.4e-13 49.9 1.6 7.7e-13 48.7 1.6 1.6 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain zf-ribbon_3 PF13248.6 KIK47798.1 - 0.0017 17.7 2.9 0.003 16.9 2.9 1.4 1 0 0 1 1 1 1 zinc-ribbon domain UPF0547 PF10571.9 KIK47798.1 - 0.0019 18.2 1.9 0.0031 17.6 1.9 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 DnaJ PF00226.31 KIK47798.1 - 0.0039 17.3 0.0 0.0081 16.3 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DZR PF12773.7 KIK47798.1 - 0.0057 16.7 0.3 0.0093 16.0 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-tcix PF14952.6 KIK47798.1 - 0.024 14.2 0.4 0.042 13.5 0.4 1.4 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding DUF35_N PF12172.8 KIK47798.1 - 0.06 13.2 2.5 0.099 12.5 2.5 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf_C2H2_10 PF18414.1 KIK47798.1 - 0.066 12.8 0.9 7.8 6.1 0.0 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-RING_7 PF02591.15 KIK47798.1 - 0.13 12.5 2.2 3.8 7.8 0.1 2.6 2 0 0 2 2 2 0 C4-type zinc ribbon domain Baculo_PEP_C PF04513.12 KIK47798.1 - 0.15 12.1 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nudix_N_2 PF14803.6 KIK47798.1 - 0.24 11.4 2.4 15 5.6 0.2 2.6 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 KIK47798.1 - 0.58 9.9 4.2 2.3 8.1 4.2 1.9 1 1 0 1 1 1 0 zinc-ribbon domain zf-IS66 PF13005.7 KIK47798.1 - 1.9 9.0 4.1 32 5.0 0.0 3.0 2 1 1 3 3 2 0 zinc-finger binding domain of transposase IS66 FAM25 PF15825.5 KIK47798.1 - 3.4 8.1 5.8 1.6 9.1 1.4 2.5 3 0 0 3 3 3 0 FAM25 family Auto_anti-p27 PF06677.12 KIK47798.1 - 7.1 6.9 6.4 33 4.8 6.7 1.8 1 1 1 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-ACC PF17848.1 KIK47798.1 - 7.9 6.6 7.6 6.8 6.9 0.3 2.8 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain HA2 PF04408.23 KIK47799.1 - 7.6e-17 61.6 0.0 1.9e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KIK47799.1 - 6.7e-14 52.2 0.0 1.6e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 KIK47799.1 - 4.4e-10 40.1 0.0 1.4e-07 32.1 0.0 2.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif DEAD PF00270.29 KIK47799.1 - 2.3e-06 27.5 0.1 5.1e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KIK47799.1 - 0.0075 16.6 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KIK47799.1 - 0.027 14.8 0.4 0.14 12.4 0.4 2.1 1 1 0 1 1 1 0 AAA domain Adaptin_N PF01602.20 KIK47800.1 - 6.9e-125 417.6 7.8 9e-125 417.2 7.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KIK47800.1 - 1.9e-38 131.1 0.0 4.1e-38 130.0 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KIK47800.1 - 3.9e-14 52.9 0.1 7.8e-14 51.9 0.1 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT PF02985.22 KIK47800.1 - 0.13 12.6 0.2 2.4 8.6 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat RasGAP PF00616.19 KIK47801.1 - 3.5e-25 89.0 0.0 6.5e-19 68.5 0.0 2.3 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KIK47801.1 - 7e-12 45.6 0.0 1.3e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain PH PF00169.29 KIK47801.1 - 0.16 12.5 0.0 0.36 11.4 0.0 1.6 1 0 0 1 1 1 0 PH domain ELO PF01151.18 KIK47802.1 - 3.9e-60 203.5 20.0 4.5e-60 203.3 20.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2231 PF09990.9 KIK47802.1 - 0.026 14.9 5.5 0.081 13.4 0.1 2.8 2 1 1 3 3 3 0 Predicted membrane protein (DUF2231) VPS13_mid_rpt PF16910.5 KIK47804.1 - 3.7e-100 334.2 9.4 5.8e-96 320.5 0.8 4.6 4 0 0 4 4 4 3 Repeating coiled region of VPS13 VPS13 PF16908.5 KIK47804.1 - 2.3e-78 263.3 5.9 6.7e-77 258.5 0.1 3.7 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KIK47804.1 - 7.5e-70 234.3 8.5 4.4e-67 225.3 0.2 3.1 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 KIK47804.1 - 4e-65 219.9 0.0 2.3e-61 207.6 0.0 3.3 2 1 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 KIK47804.1 - 3.7e-29 101.2 0.3 1.3e-28 99.4 0.1 2.2 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KIK47804.1 - 2.3e-09 37.5 0.0 2.6e-08 34.1 0.0 2.8 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain DENN PF02141.21 KIK47805.1 - 1.5e-18 67.4 0.0 1.5e-17 64.2 0.0 2.3 1 1 0 1 1 1 1 DENN (AEX-3) domain YabA PF06156.13 KIK47805.1 - 2.3 8.9 7.8 12 6.6 1.0 2.8 3 0 0 3 3 3 0 Initiation control protein YabA AGTRAP PF06396.11 KIK47806.1 - 0.0034 17.2 0.1 0.0081 16.0 0.1 1.7 1 1 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) Mg_trans_NIPA PF05653.14 KIK47808.1 - 5.7e-20 71.6 7.1 6.4e-10 38.6 0.4 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA DUF3292 PF11696.8 KIK47810.1 - 4.8e-09 35.2 1.0 7.1e-05 21.4 0.5 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3292) PRT_C PF08372.10 KIK47810.1 - 0.038 13.8 0.6 0.069 12.9 0.1 1.7 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal ACDC PF14733.6 KIK47810.1 - 0.07 13.5 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AP2-coincident C-terminal Reticulon PF02453.17 KIK47810.1 - 0.17 11.8 1.5 1.9 8.4 0.7 2.2 2 0 0 2 2 2 0 Reticulon Rad21_Rec8_N PF04825.13 KIK47811.1 - 3.4e-23 81.9 0.0 6.1e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KIK47811.1 - 7.4e-06 25.2 0.0 2e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein NUDIX PF00293.28 KIK47812.1 - 2.2e-25 89.2 0.0 2.8e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Blt1 PF12754.7 KIK47814.1 - 0.025 14.9 0.1 13 6.1 1.2 2.3 2 0 0 2 2 2 0 Blt1 N-terminal domain SUIM_assoc PF16619.5 KIK47814.1 - 6.2 7.0 10.6 1.4 9.1 6.6 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MPC PF03650.13 KIK47815.1 - 4.2e-34 117.0 0.1 4.8e-34 116.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DNA_ligase_A_M PF01068.21 KIK47816.1 - 1.1e-64 217.9 0.2 1.7e-64 217.3 0.2 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KIK47816.1 - 1e-45 156.2 0.6 1.9e-45 155.3 0.6 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KIK47816.1 - 1.3e-25 89.9 0.0 3.1e-25 88.6 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KIK47816.1 - 0.00013 22.4 0.0 0.00028 21.2 0.0 1.6 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 KIK47816.1 - 0.067 13.2 0.1 11 6.1 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain Ribosomal_S17_N PF16205.5 KIK47817.1 - 7.9e-32 109.5 1.1 1.5e-31 108.6 1.1 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KIK47817.1 - 2.9e-28 97.8 2.4 5.9e-28 96.8 2.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 DUF922 PF06037.11 KIK47817.1 - 0.088 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) Metallophos PF00149.28 KIK47818.1 - 5.7e-38 131.5 0.0 2.5e-37 129.4 0.0 1.8 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KIK47818.1 - 2.1e-17 63.3 0.0 3.7e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain EamA PF00892.20 KIK47819.1 - 0.0022 18.2 10.3 0.0022 18.2 10.3 3.9 3 1 1 4 4 4 2 EamA-like transporter family Ribosomal_L36 PF00444.18 KIK47820.1 - 6.9e-21 74.2 12.1 8.6e-21 73.9 12.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L36 Arc_trans_TRASH PF08394.10 KIK47820.1 - 0.018 15.4 1.3 0.027 14.8 1.3 1.3 1 0 0 1 1 1 0 Archaeal TRASH domain DHFR_1 PF00186.19 KIK47821.1 - 4.3e-27 94.8 0.0 9e-27 93.7 0.0 1.5 1 1 0 1 1 1 1 Dihydrofolate reductase SGS PF05002.15 KIK47822.1 - 2.9e-32 110.6 3.1 4.1e-32 110.1 3.1 1.2 1 0 0 1 1 1 1 SGS domain CS PF04969.16 KIK47822.1 - 1.3e-08 35.8 0.0 2.8e-08 34.7 0.0 1.6 2 0 0 2 2 2 1 CS domain GST_N_3 PF13417.6 KIK47823.1 - 8.6e-10 38.9 0.0 3.5e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK47823.1 - 1.1e-08 35.3 0.0 2.6e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK47823.1 - 0.00019 21.4 0.0 0.00036 20.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIK47823.1 - 0.0013 18.9 0.0 0.0053 16.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK47823.1 - 0.0018 18.4 0.0 0.0067 16.6 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KIK47823.1 - 0.0057 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain YopE_N PF09020.10 KIK47823.1 - 0.0099 16.1 0.3 0.017 15.4 0.3 1.3 1 0 0 1 1 1 1 YopE, N terminal Galactosyl_T PF01762.21 KIK47824.1 - 2e-06 27.8 0.0 0.0013 18.6 0.0 2.5 2 1 0 2 2 2 2 Galactosyltransferase DUF5441 PF17513.2 KIK47825.1 - 0.021 14.6 0.1 0.035 13.8 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5441) PMP1_2 PF08114.11 KIK47826.1 - 0.043 13.5 0.6 0.072 12.8 0.6 1.2 1 0 0 1 1 1 0 ATPase proteolipid family OppC_N PF12911.7 KIK47826.1 - 0.055 13.5 3.4 0.061 13.3 1.5 2.0 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Mid2 PF04478.12 KIK47826.1 - 0.061 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor MGC-24 PF05283.11 KIK47826.1 - 0.57 10.6 5.0 0.17 12.3 2.1 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Isochorismatase PF00857.20 KIK47827.1 - 2.3e-05 24.7 0.0 0.00027 21.2 0.0 2.0 2 0 0 2 2 2 1 Isochorismatase family Sde2_N_Ubi PF13019.6 KIK47827.1 - 0.026 14.4 0.0 0.032 14.1 0.0 1.1 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Isochorismatase PF00857.20 KIK47828.1 - 2.4e-05 24.6 0.1 2.6e-05 24.5 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family F-box-like PF12937.7 KIK47829.1 - 0.00041 20.2 1.1 0.00092 19.1 1.1 1.6 1 0 0 1 1 1 1 F-box-like UBD PF16455.5 KIK47830.1 - 0.07 13.4 0.8 0.73 10.1 0.4 2.2 1 1 1 2 2 2 0 Ubiquitin-binding domain Ras PF00071.22 KIK47831.1 - 4.6e-42 143.4 0.0 5.7e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK47831.1 - 1.8e-22 79.8 0.0 2.7e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK47831.1 - 4.7e-09 35.9 0.0 6.1e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIK47831.1 - 8.9e-05 22.1 0.0 0.00017 21.2 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FAD-SLDH PF12318.8 KIK47831.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 1 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase D-ser_dehydrat PF14031.6 KIK47832.1 - 3.3e-26 91.8 0.0 2e-25 89.3 0.0 2.2 2 1 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KIK47832.1 - 3.1e-10 40.1 0.0 4.5e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Abhydrolase_3 PF07859.13 KIK47833.1 - 5.6e-62 209.3 0.0 6.7e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIK47833.1 - 1.2e-06 27.7 0.0 1.5e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KIK47833.1 - 1.3e-06 27.6 0.0 4.3e-06 25.9 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KIK47833.1 - 0.00035 20.1 0.0 0.00069 19.2 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Ribonuc_L-PSP PF01042.21 KIK47834.1 - 3.5e-33 114.2 0.0 4.1e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP UBZ_FAAP20 PF15750.5 KIK47834.1 - 0.16 11.9 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-binding zinc-finger RRM_1 PF00076.22 KIK47836.1 - 4.3e-39 132.2 0.4 3.4e-20 71.6 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KIK47836.1 - 7e-14 52.7 2.2 2.2e-12 47.9 2.2 2.6 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.11 KIK47836.1 - 1.4e-05 25.0 0.4 0.0051 16.8 0.0 3.1 2 1 1 3 3 3 1 RNA binding motif RRM_7 PF16367.5 KIK47836.1 - 0.063 13.4 0.0 0.29 11.3 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif RRM_5 PF13893.6 KIK47836.1 - 0.074 12.7 0.0 8.4 6.0 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KIK47836.1 - 0.085 12.9 0.2 12 6.0 0.1 3.1 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif IlvN PF07991.12 KIK47837.1 - 4.2e-48 163.0 0.1 6.9e-48 162.3 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KIK47837.1 - 4.4e-22 78.9 0.2 6.6e-22 78.4 0.2 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 KIK47837.1 - 1.1e-09 38.7 0.1 2.5e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KIK47837.1 - 2e-05 24.8 0.0 3.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KIK47837.1 - 0.00033 20.1 0.0 0.00055 19.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KIK47837.1 - 0.0086 16.1 0.1 0.15 12.0 0.1 2.2 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 KIK47837.1 - 0.025 14.8 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KIK47837.1 - 0.066 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.6 KIK47838.1 - 2.8e-57 194.0 0.1 3.4e-57 193.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK47838.1 - 8.1e-41 139.6 0.5 1e-40 139.3 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK47838.1 - 1e-08 35.3 0.1 1.5e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF2620 PF10941.8 KIK47838.1 - 0.017 15.3 0.1 0.042 14.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF2620 Sybindin PF04099.12 KIK47838.1 - 0.045 13.7 0.0 0.065 13.2 0.0 1.4 1 1 0 1 1 1 0 Sybindin-like family Cupin_2 PF07883.11 KIK47839.1 - 8e-06 25.5 0.2 1.9e-05 24.3 0.1 1.7 2 0 0 2 2 2 1 Cupin domain Pex16 PF08610.10 KIK47840.1 - 2.2e-104 349.2 3.6 2.4e-104 349.0 3.6 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Nsp1_C PF05064.13 KIK47841.1 - 2.7e-31 107.8 0.1 7.5e-31 106.3 0.0 1.7 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KIK47841.1 - 0.00066 20.5 24.1 0.0012 19.6 22.6 2.3 2 1 0 2 2 2 1 Nucleoporin FG repeat region Syntaxin-6_N PF09177.11 KIK47841.1 - 0.023 15.3 0.5 3.1 8.4 0.1 2.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal NPV_P10 PF05531.12 KIK47841.1 - 0.023 15.2 3.3 25 5.4 0.1 3.4 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein EIAV_Rev PF11129.8 KIK47841.1 - 0.039 14.1 0.0 0.22 11.7 0.0 2.0 2 0 0 2 2 2 0 Rev protein of equine infectious anaemia virus CENP-Q PF13094.6 KIK47841.1 - 0.044 14.0 5.0 1.5 9.0 5.0 2.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Laminin_II PF06009.12 KIK47841.1 - 0.053 13.5 0.5 13 5.8 0.0 2.4 2 0 0 2 2 2 0 Laminin Domain II Spot_14 PF07084.12 KIK47841.1 - 0.055 13.6 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 FlaC_arch PF05377.11 KIK47841.1 - 0.061 13.7 1.6 4.2 7.8 0.1 3.6 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 KIK47841.1 - 0.067 13.5 1.6 26 5.2 0.0 3.4 3 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ZapB PF06005.12 KIK47843.1 - 0.018 15.5 7.8 0.018 15.5 7.8 2.4 2 0 0 2 2 2 0 Cell division protein ZapB CorA PF01544.18 KIK47844.1 - 2.2e-20 73.1 5.3 5.9e-14 52.1 0.4 2.5 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein MWFE PF15879.5 KIK47844.1 - 0.012 15.8 0.0 0.039 14.1 0.0 1.9 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase MWFE subunit RSRP PF17069.5 KIK47844.1 - 7.9 6.0 30.1 16 5.0 30.1 1.4 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 SR-25 PF10500.9 KIK47844.1 - 9.4 5.8 31.4 0.69 9.5 26.0 1.8 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2235 PF09994.9 KIK47845.1 - 8.7e-82 274.7 0.0 1.3e-81 274.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Hydrolase_4 PF12146.8 KIK47845.1 - 0.058 12.7 0.1 0.099 11.9 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Prenyltransf PF01255.19 KIK47846.1 - 0.092 12.2 0.0 2.3 7.7 0.0 2.3 2 1 0 2 2 2 0 Putative undecaprenyl diphosphate synthase PGM_PMM_I PF02878.16 KIK47847.1 - 1.7e-16 60.2 0.3 2.5e-07 30.5 0.0 2.9 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KIK47847.1 - 1.5e-11 44.3 0.7 4.3e-11 42.8 0.7 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 KIK47847.1 - 0.053 14.1 0.0 1.8 9.3 0.1 3.1 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II GATase_4 PF13230.6 KIK47848.1 - 7.8e-21 74.2 0.0 1.7e-20 73.1 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 KIK47848.1 - 1.5e-10 41.4 0.0 3.5e-10 40.2 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain ICE2 PF08426.10 KIK47849.1 - 6.6e-26 91.3 32.5 4.9e-15 55.5 14.7 2.9 1 1 1 2 2 2 2 ICE2 MoaE PF02391.17 KIK47850.1 - 2.9e-39 133.9 0.2 3.6e-39 133.5 0.2 1.1 1 0 0 1 1 1 1 MoaE protein OspE PF02471.17 KIK47850.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Borrelia outer surface protein E Indigoidine_A PF04227.12 KIK47851.1 - 3.6e-126 420.4 0.4 5.5e-126 419.8 0.4 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KIK47851.1 - 6.8e-17 61.7 0.1 4.7e-09 36.0 0.0 2.6 2 1 0 2 2 2 2 pfkB family carbohydrate kinase LPD38 PF18857.1 KIK47851.1 - 0.0007 19.8 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 Large polyvalent protein associated domain 38 ResIII PF04851.15 KIK47852.1 - 1.1e-20 74.4 0.0 2.6e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIK47852.1 - 6.7e-17 61.8 0.0 2.4e-16 60.0 0.0 2.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK47852.1 - 2.5e-12 46.9 0.0 5.3e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.23 KIK47852.1 - 0.0025 16.6 0.0 0.0075 15.0 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF2075 PF09848.9 KIK47852.1 - 0.0083 15.4 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD_2 PF06733.15 KIK47852.1 - 0.058 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 T2SSE PF00437.20 KIK47852.1 - 0.064 12.3 0.1 0.39 9.7 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 KIK47852.1 - 0.14 12.5 0.0 0.37 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mito_carr PF00153.27 KIK47853.1 - 9.8e-64 211.3 7.3 7.2e-24 83.5 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PINIT PF14324.6 KIK47854.1 - 1e-37 129.7 0.3 1.9e-37 128.8 0.3 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KIK47854.1 - 6.9e-17 60.9 10.3 1.2e-16 60.2 10.3 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KIK47854.1 - 8.2e-07 28.8 3.5 2.2e-06 27.4 3.5 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 KIK47854.1 - 0.0057 16.4 2.4 0.057 13.2 0.0 2.9 3 0 0 3 3 3 1 SAP domain MRC1 PF09444.10 KIK47854.1 - 0.25 11.9 3.7 25 5.3 0.2 3.1 2 1 1 3 3 3 0 MRC1-like domain Colicin_Pyocin PF01320.18 KIK47854.1 - 0.26 11.4 0.6 0.97 9.6 0.2 2.1 3 0 0 3 3 3 0 Colicin immunity protein / pyocin immunity protein zf-Sec23_Sec24 PF04810.15 KIK47854.1 - 0.59 10.2 3.7 1.8 8.7 3.7 1.9 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger CS PF04969.16 KIK47855.1 - 2.8e-19 69.9 1.2 3.4e-19 69.6 0.5 1.5 2 0 0 2 2 2 1 CS domain WD40 PF00400.32 KIK47856.1 - 9e-12 45.3 3.3 9e-05 23.2 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Tim17 PF02466.19 KIK47857.1 - 2.9e-06 27.6 14.1 5.3e-06 26.8 14.0 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family BRCT_2 PF16589.5 KIK47858.1 - 9.7e-10 38.7 0.0 1e-08 35.5 0.0 2.3 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Pkinase PF00069.25 KIK47859.1 - 0.0021 17.4 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KIK47859.1 - 0.021 14.2 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KIK47859.1 - 0.12 11.7 1.2 0.22 10.8 1.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK47859.1 - 0.18 10.5 0.1 0.26 10.0 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Ribosomal_S9 PF00380.19 KIK47860.1 - 2.6e-30 105.4 0.5 3e-30 105.2 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L4 PF00573.22 KIK47861.1 - 1.6e-58 197.6 0.0 2e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family 2-Hacid_dh_C PF02826.19 KIK47862.1 - 6.7e-52 175.4 0.0 2.2e-51 173.7 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIK47862.1 - 6.7e-33 113.2 0.0 9.8e-33 112.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIK47862.1 - 0.052 13.7 0.1 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Peptidase_M15_4 PF13539.6 KIK47862.1 - 0.06 13.9 0.0 0.38 11.3 0.0 2.1 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase AdoHcyase_NAD PF00670.21 KIK47862.1 - 0.099 12.7 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain His_biosynth PF00977.21 KIK47863.1 - 3.5e-41 141.1 0.1 1.7e-40 138.9 0.1 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KIK47863.1 - 1.9e-17 63.7 0.0 3.1e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KIK47863.1 - 1.5e-07 31.5 0.0 4e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KIK47863.1 - 4.7e-06 26.3 0.0 8.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 KIK47863.1 - 0.013 15.2 0.1 0.72 9.6 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 EphA2_TM PF14575.6 KIK47863.1 - 0.1 13.5 0.1 0.21 12.5 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pal1 PF08316.11 KIK47864.1 - 4.4e-17 63.1 0.1 1.1e-16 61.8 0.1 1.7 1 0 0 1 1 1 1 Pal1 cell morphology protein KIF1B PF12423.8 KIK47864.1 - 6.6 7.3 7.8 26 5.3 0.2 3.5 3 0 0 3 3 3 0 Kinesin protein 1B FA_desaturase PF00487.24 KIK47865.1 - 4.2e-26 92.3 27.7 6.2e-26 91.8 27.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KIK47865.1 - 2.3e-08 34.1 0.0 5.8e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_L13e PF01294.18 KIK47866.1 - 1.9e-74 249.4 6.5 2.5e-74 249.0 6.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e TMEM154 PF15102.6 KIK47868.1 - 0.72 9.8 4.4 0.24 11.3 0.2 2.2 3 0 0 3 3 3 0 TMEM154 protein family SPX PF03105.19 KIK47868.1 - 7.4 6.4 9.1 28 4.5 9.1 1.9 1 1 0 1 1 1 0 SPX domain Trs65 PF12735.7 KIK47869.1 - 0.13 11.7 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 TT_ORF1 PF02956.14 KIK47869.1 - 3.3 6.3 5.2 4 6.0 5.2 1.1 1 0 0 1 1 1 0 TT viral orf 1 Leu_Phe_trans PF03588.14 KIK47870.1 - 0.042 13.4 0.9 0.19 11.2 0.1 2.2 2 1 1 3 3 3 0 Leucyl/phenylalanyl-tRNA protein transferase WD40 PF00400.32 KIK47871.1 - 9e-44 146.6 12.8 8.5e-09 35.9 0.6 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK47871.1 - 2.3e-09 37.4 0.0 0.1 12.9 0.0 5.0 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK47871.1 - 0.012 15.4 0.0 1.8 8.4 0.0 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK47871.1 - 0.013 14.2 2.7 4.9 5.7 0.2 3.4 3 1 1 4 4 4 0 Nucleoporin Nup120/160 GAIN_A PF18619.1 KIK47872.1 - 0.62 10.3 3.5 15 5.9 0.1 3.0 3 0 0 3 3 3 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A MFS_1 PF07690.16 KIK47873.1 - 3.2e-39 134.8 27.6 6.8e-31 107.5 7.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK47873.1 - 3.1e-05 23.0 10.5 3.1e-05 23.0 10.5 2.9 2 2 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KIK47873.1 - 3.6e-05 22.8 14.7 0.00085 18.3 6.0 2.3 2 0 0 2 2 2 2 MFS_1 like family OATP PF03137.20 KIK47873.1 - 0.00029 19.3 1.3 0.00029 19.3 1.3 2.3 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 KIK47873.1 - 0.00038 19.9 7.1 0.00038 19.9 7.1 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB UNC-93 PF05978.16 KIK47873.1 - 0.88 9.3 6.8 0.072 12.8 0.6 2.1 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 CPP1-like PF11833.8 KIK47873.1 - 6.3 6.4 12.7 0.098 12.3 3.7 2.5 3 1 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Fapy_DNA_glyco PF01149.24 KIK47875.1 - 3.2e-28 98.7 0.0 6.6e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KIK47875.1 - 1.7e-19 69.5 0.0 2.9e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 KIK47875.1 - 0.011 14.5 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_S13 PF00416.22 KIK47875.1 - 0.052 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S13/S18 DEAD PF00270.29 KIK47876.1 - 2.7e-36 125.0 0.1 4.3e-36 124.3 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK47876.1 - 6.2e-27 94.1 0.1 1.1e-24 86.9 0.0 2.7 2 1 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KIK47876.1 - 8.3e-09 35.7 0.0 1.5e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Mito_carr PF00153.27 KIK47877.1 - 2.9e-51 171.4 0.6 2.2e-17 62.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DEAD PF00270.29 KIK47878.1 - 1.6e-37 128.9 0.0 3.1e-37 128.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK47878.1 - 5.5e-23 81.4 0.0 1.2e-22 80.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK47878.1 - 2.9e-06 27.4 0.0 5.1e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HMG_box PF00505.19 KIK47880.1 - 1.1e-15 57.7 2.3 3.3e-15 56.3 2.3 1.7 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK47880.1 - 7.6e-09 36.0 0.2 1.1e-08 35.6 0.2 1.3 1 1 0 1 1 1 1 HMG-box domain PolyA_pol PF01743.20 KIK47881.1 - 6.8e-25 87.9 0.1 1.7e-24 86.7 0.1 1.7 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KIK47881.1 - 5.3e-05 22.9 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Ras PF00071.22 KIK47882.1 - 6.3e-58 194.9 0.2 7.4e-58 194.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK47882.1 - 1.2e-32 112.7 0.0 2e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK47882.1 - 5.6e-15 55.2 0.0 7e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIK47882.1 - 1.4e-07 31.6 0.0 3.1e-07 30.5 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KIK47882.1 - 3.5e-07 29.8 0.0 4.4e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KIK47882.1 - 3.7e-06 26.6 0.0 0.00015 21.3 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIK47882.1 - 5.1e-05 23.2 0.3 0.0045 16.9 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 KIK47882.1 - 0.00042 20.2 0.4 0.017 14.9 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KIK47882.1 - 0.00053 19.8 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 KIK47882.1 - 0.0011 18.3 0.3 0.046 13.0 0.0 2.2 2 1 0 2 2 2 1 Septin cobW PF02492.19 KIK47882.1 - 0.0035 17.0 0.0 0.012 15.2 0.0 1.8 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 KIK47882.1 - 0.0047 16.4 0.0 0.0071 15.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KIK47882.1 - 0.007 16.6 0.0 0.017 15.4 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KIK47882.1 - 0.01 16.2 0.0 0.016 15.6 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KIK47882.1 - 0.014 15.4 0.1 0.041 13.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KIK47882.1 - 0.015 15.0 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK47882.1 - 0.018 14.6 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KIK47882.1 - 0.034 14.7 0.0 0.93 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KIK47882.1 - 0.049 13.5 0.7 0.091 12.7 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 KIK47882.1 - 0.056 13.3 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 NTPase Glyco_hydro_75 PF07335.11 KIK47882.1 - 0.066 13.5 0.1 0.093 13.0 0.1 1.5 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 NACHT PF05729.12 KIK47882.1 - 0.079 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KIK47882.1 - 0.12 12.9 0.0 0.48 10.9 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Glucosamine_iso PF01182.20 KIK47883.1 - 1e-77 261.1 0.0 1.1e-77 260.9 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Lac_bphage_repr PF06543.12 KIK47883.1 - 0.015 15.3 0.4 0.039 13.9 0.4 1.6 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor PXA PF02194.15 KIK47884.1 - 6.1e-39 133.9 0.2 8.2e-39 133.5 0.2 1.2 1 0 0 1 1 1 1 PXA domain m04gp34like PF12216.8 KIK47885.1 - 0.17 11.5 0.9 0.29 10.7 0.1 1.7 2 0 0 2 2 2 0 Immune evasion protein Aminotran_4 PF01063.19 KIK47888.1 - 1.8e-32 113.0 0.0 2.4e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV PWI PF01480.17 KIK47890.1 - 8.3e-10 38.9 0.0 1.6e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 KIK47890.1 - 1.3e-05 25.0 4.0 2.1e-05 24.3 4.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIK47890.1 - 0.0015 18.5 6.6 0.0026 17.8 6.6 1.4 1 0 0 1 1 1 1 Zinc finger domain PRKG1_interact PF15898.5 KIK47890.1 - 0.28 12.1 4.1 0.62 11.0 4.1 1.6 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain zf-CCCH_2 PF14608.6 KIK47890.1 - 0.73 10.4 1.9 1.2 9.8 1.9 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Glucodextran_N PF09137.11 KIK47892.1 - 0.077 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Glucodextranase, domain N NrfD_2 PF14589.6 KIK47892.1 - 0.1 12.6 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Polysulfide reductase ABC_membrane PF00664.23 KIK47893.1 - 3.3e-52 177.8 15.0 1.2e-28 100.6 1.7 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK47893.1 - 3.4e-42 144.2 0.0 4.2e-26 92.1 0.0 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIK47893.1 - 1.1e-12 47.9 3.6 0.00021 20.8 0.2 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIK47893.1 - 1.2e-05 25.8 0.3 0.22 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KIK47893.1 - 1.8e-05 24.4 0.0 0.19 11.3 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 KIK47893.1 - 2.7e-05 24.8 0.1 0.014 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KIK47893.1 - 6.9e-05 22.8 2.2 0.81 9.4 0.1 4.1 2 2 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIK47893.1 - 8.6e-05 22.2 0.7 0.3 10.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 KIK47893.1 - 9e-05 22.1 0.1 0.075 12.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF87 PF01935.17 KIK47893.1 - 0.00017 21.7 0.4 0.09 12.9 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 KIK47893.1 - 0.00072 18.7 0.0 0.069 12.2 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Adeno_IVa2 PF02456.15 KIK47893.1 - 0.0014 17.5 0.0 0.015 14.1 0.0 2.3 2 0 0 2 2 2 1 Adenovirus IVa2 protein RsgA_GTPase PF03193.16 KIK47893.1 - 0.0021 18.0 0.4 2.8 7.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KIK47893.1 - 0.0031 17.6 0.7 0.47 10.5 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DEAD PF00270.29 KIK47893.1 - 0.0034 17.2 0.1 1.7 8.4 0.0 2.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.18 KIK47893.1 - 0.0051 16.2 0.3 0.53 9.6 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.6 KIK47893.1 - 0.0055 17.0 0.4 2.9 8.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KIK47893.1 - 0.023 14.8 0.9 0.79 9.8 0.0 2.6 2 0 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.17 KIK47893.1 - 0.051 13.3 0.0 5.2 6.8 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Pox_A32 PF04665.12 KIK47893.1 - 0.06 12.8 1.1 5.7 6.3 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_5 PF07728.14 KIK47893.1 - 0.061 13.3 0.6 19 5.2 0.1 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KIK47893.1 - 0.069 12.9 0.6 1.5 8.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KIK47893.1 - 0.076 12.8 0.0 0.53 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KIK47893.1 - 0.079 13.2 0.0 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ResIII PF04851.15 KIK47893.1 - 0.11 12.5 0.0 4.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DPM3 PF08285.11 KIK47893.1 - 0.11 12.7 0.1 0.65 10.2 0.1 2.4 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) AAA PF00004.29 KIK47893.1 - 0.16 12.4 0.5 2.5 8.5 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KIK47893.1 - 0.79 9.3 2.5 3.4 7.2 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RhoGAP PF00620.27 KIK47894.1 - 3.1e-42 144.0 0.1 1.8e-41 141.5 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 KIK47894.1 - 5.9e-08 32.9 0.7 5.9e-08 32.9 0.7 3.2 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Ccdc124 PF06244.12 KIK47894.1 - 0.34 11.5 1.6 0.81 10.2 1.6 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 UvrD_C_2 PF13538.6 KIK47895.1 - 0.019 14.8 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF5605 PF18310.1 KIK47895.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5605) PIF1 PF05970.14 KIK47896.1 - 6.8e-22 78.1 0.1 8.6e-22 77.8 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIK47896.1 - 7.2e-12 45.4 0.0 1.1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain Cauli_VI PF01693.16 KIK47896.1 - 8.5e-11 42.0 0.0 1.4e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin ABC_tran PF00005.27 KIK47896.1 - 3.6e-05 24.3 0.2 0.00012 22.6 0.3 1.8 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 KIK47896.1 - 5.3e-05 23.7 0.1 8e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KIK47896.1 - 0.00012 22.4 0.1 0.00025 21.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIK47896.1 - 0.00022 20.9 0.0 0.00097 18.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SSE PF00437.20 KIK47896.1 - 0.00048 19.3 0.0 0.00066 18.8 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 KIK47896.1 - 0.00075 18.9 0.1 0.0011 18.4 0.1 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 KIK47896.1 - 0.0015 19.0 0.1 0.0022 18.4 0.1 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIK47896.1 - 0.0017 17.9 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region PhoH PF02562.16 KIK47896.1 - 0.0046 16.4 0.0 0.0059 16.1 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 KIK47896.1 - 0.0051 17.1 0.1 0.012 15.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain Guanylate_kin PF00625.21 KIK47896.1 - 0.0054 16.4 0.1 3.6 7.3 0.0 2.2 2 0 0 2 2 2 2 Guanylate kinase TsaE PF02367.17 KIK47896.1 - 0.016 15.2 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KIK47896.1 - 0.018 15.0 0.0 0.039 13.9 0.0 1.5 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KIK47896.1 - 0.022 14.7 0.1 0.042 13.8 0.1 1.4 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 KIK47896.1 - 0.027 14.4 0.1 0.054 13.4 0.1 1.5 1 0 0 1 1 1 0 NTPase IstB_IS21 PF01695.17 KIK47896.1 - 0.087 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 KIK47896.1 - 0.087 12.8 0.2 0.22 11.5 0.1 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.9 KIK47896.1 - 0.11 11.4 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MeaB PF03308.16 KIK47896.1 - 0.11 11.5 0.3 0.24 10.4 0.3 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 KIK47896.1 - 0.13 12.4 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK47896.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KIK47896.1 - 0.14 12.5 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 KIK47896.1 - 0.14 11.8 0.0 0.35 10.6 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.13 KIK47896.1 - 0.15 11.2 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Lon_2 PF13337.6 KIK47896.1 - 0.18 10.3 0.0 0.26 9.8 0.0 1.1 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease AAA_18 PF13238.6 KIK47896.1 - 0.19 12.2 0.3 0.32 11.5 0.3 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KIK47896.1 - 0.2 10.9 0.4 0.35 10.1 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 KIK47896.1 - 0.55 10.1 0.0 0.55 10.1 0.0 1.7 2 1 0 2 2 2 0 RsgA GTPase PIF1 PF05970.14 KIK47900.1 - 1.6e-13 50.6 0.0 1.8e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase SH3_13 PF18335.1 KIK47900.1 - 0.00029 20.6 0.0 0.00049 19.9 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain PIF1 PF05970.14 KIK47901.1 - 4.2e-19 69.0 0.1 5.1e-19 68.7 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIK47901.1 - 6.3e-08 32.6 0.0 7.9e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK47901.1 - 4.9e-05 23.8 0.3 6.9e-05 23.3 0.3 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KIK47901.1 - 0.0032 17.8 0.0 0.01 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KIK47901.1 - 0.0041 17.6 0.0 0.0068 16.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter PhoH PF02562.16 KIK47901.1 - 0.0096 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA_7 PF12775.7 KIK47901.1 - 0.011 15.2 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KIK47901.1 - 0.032 14.0 0.0 0.65 9.7 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.6 KIK47901.1 - 0.036 13.8 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 KIK47901.1 - 0.036 14.0 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 KIK47901.1 - 0.043 14.1 0.1 0.068 13.4 0.1 1.4 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIK47901.1 - 0.058 12.6 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain T2SSE PF00437.20 KIK47901.1 - 0.063 12.3 0.0 0.087 11.9 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein TsaE PF02367.17 KIK47901.1 - 0.083 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KIK47901.1 - 0.084 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KIK47901.1 - 0.087 12.1 0.2 0.098 11.9 0.2 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.7 KIK47901.1 - 0.087 11.7 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain DUF815 PF05673.13 KIK47901.1 - 0.095 11.8 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 KIK47901.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase Viral_helicase1 PF01443.18 KIK47901.1 - 0.14 11.9 0.1 0.75 9.5 0.1 1.9 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 KIK47901.1 - 0.14 12.3 0.1 0.19 11.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 KIK47901.1 - 0.17 10.8 0.1 0.22 10.4 0.1 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Ysc84 PF04366.12 KIK47902.1 - 8.8e-38 128.9 0.3 1.4e-37 128.3 0.3 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KIK47902.1 - 2.2e-17 62.4 0.1 6.2e-17 60.9 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK47902.1 - 6.2e-14 51.6 0.0 2.3e-13 49.8 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KIK47902.1 - 9.2e-13 47.7 0.0 9e-12 44.5 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain Las1 PF04031.13 KIK47903.1 - 4.8e-46 156.7 2.8 1e-45 155.6 2.2 1.8 2 0 0 2 2 2 1 Las1-like B-block_TFIIIC PF04182.12 KIK47904.1 - 1.3e-08 34.9 0.2 9.2e-07 28.9 0.0 2.5 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC HTH_24 PF13412.6 KIK47904.1 - 0.0049 16.4 0.3 0.12 12.0 0.0 2.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 KIK47904.1 - 0.083 13.4 0.1 0.89 10.1 0.0 3.0 2 0 0 2 2 2 0 Winged helix DNA-binding domain HAD_2 PF13419.6 KIK47905.1 - 3e-23 82.8 0.0 5.3e-23 82.0 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIK47905.1 - 6.5e-10 39.7 0.0 0.00086 19.6 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIK47905.1 - 1.8e-08 34.3 0.0 3.1e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KIK47905.1 - 0.038 14.4 0.1 0.11 12.9 0.1 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KIK47905.1 - 0.05 13.7 0.0 2.1 8.5 0.0 2.9 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ABC_tran PF00005.27 KIK47906.1 - 1.2e-32 113.3 0.1 4.4e-17 62.9 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIK47906.1 - 2.6e-11 43.9 2.1 0.13 12.1 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIK47906.1 - 3.1e-10 39.9 5.1 0.0031 17.0 0.0 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KIK47906.1 - 6.1e-05 22.9 0.0 0.25 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIK47906.1 - 8.4e-05 22.5 0.4 0.33 10.9 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase NACHT PF05729.12 KIK47906.1 - 0.00018 21.5 0.6 0.028 14.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 KIK47906.1 - 0.0002 21.8 0.0 0.54 10.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK47906.1 - 0.00032 21.1 0.1 0.2 12.0 0.0 2.7 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIK47906.1 - 0.00075 19.8 0.0 0.26 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIK47906.1 - 0.0016 18.6 0.0 0.54 10.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KIK47906.1 - 0.0027 17.5 0.4 0.8 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KIK47906.1 - 0.0036 17.0 1.8 0.41 10.3 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_29 PF13555.6 KIK47906.1 - 0.0046 16.7 1.5 1.3 8.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 KIK47906.1 - 0.0049 17.1 0.0 2.5 8.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KIK47906.1 - 0.0058 16.6 0.0 0.43 10.5 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain SbcCD_C PF13558.6 KIK47906.1 - 0.0066 16.7 0.0 6 7.2 0.0 3.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KIK47906.1 - 0.0076 16.8 5.5 0.064 13.8 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KIK47906.1 - 0.016 15.2 0.9 0.35 10.9 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KIK47906.1 - 0.017 15.5 0.0 4.6 7.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_13 PF13166.6 KIK47906.1 - 0.018 13.7 1.2 0.058 12.0 0.0 2.2 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 KIK47906.1 - 0.022 14.0 0.0 0.79 8.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 KIK47906.1 - 0.024 14.4 0.3 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KIK47906.1 - 0.024 15.2 0.0 5.9 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF3557 PF12078.8 KIK47906.1 - 0.032 14.2 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3557) TniB PF05621.11 KIK47906.1 - 0.06 12.7 0.0 0.41 10.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein TsaE PF02367.17 KIK47906.1 - 0.063 13.3 1.4 0.2 11.7 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 KIK47906.1 - 0.091 13.0 0.4 0.98 9.6 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase VirE PF05272.11 KIK47906.1 - 0.11 12.3 0.0 8.1 6.1 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E Sigma54_activ_2 PF14532.6 KIK47906.1 - 0.11 12.7 0.1 0.34 11.0 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 KIK47906.1 - 0.21 11.7 0.6 22 5.2 0.1 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_7 PF12775.7 KIK47906.1 - 0.28 10.7 1.6 1.3 8.5 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF4399 PF14347.6 KIK47907.1 - 0.21 12.0 1.2 0.45 10.9 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) GHMP_kinases_N PF00288.26 KIK47908.1 - 1.6e-09 37.8 0.1 3.1e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KIK47908.1 - 0.0005 20.4 0.0 0.0013 19.0 0.0 1.8 1 1 0 1 1 1 1 GHMP kinases C terminal Asp PF00026.23 KIK47909.1 - 1.8e-41 142.6 4.1 1.1e-39 136.7 4.1 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KIK47909.1 - 4.9e-07 30.3 1.0 9.4e-06 26.2 0.5 2.6 2 0 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.6 KIK47909.1 - 4.7e-06 27.0 1.3 0.02 15.1 0.3 2.7 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 KIK47909.1 - 9.9e-06 26.0 1.4 2.4e-05 24.8 0.3 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KIK47909.1 - 0.0054 16.5 0.0 0.02 14.6 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Helicase_C PF00271.31 KIK47911.1 - 2.8e-20 72.7 0.1 5.5e-20 71.8 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK47911.1 - 7e-18 65.2 0.0 1.7e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIK47911.1 - 8.3e-17 61.5 0.0 2.9e-16 59.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase F-box PF00646.33 KIK47913.1 - 0.00024 20.9 0.0 0.00084 19.2 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK47913.1 - 0.0004 20.2 0.3 0.001 18.9 0.3 1.7 1 0 0 1 1 1 1 F-box-like Prenylcys_lyase PF07156.14 KIK47914.1 - 1.2e-70 238.5 0.0 1.6e-70 238.1 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 KIK47914.1 - 1.3e-08 34.5 0.1 1.2e-07 31.4 0.0 2.2 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIK47914.1 - 1.4e-08 34.9 1.2 1.9e-08 34.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIK47914.1 - 6.3e-07 29.3 0.3 0.016 14.8 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIK47914.1 - 0.00066 19.7 0.0 0.03 14.3 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KIK47914.1 - 0.04 13.1 0.0 0.19 10.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK47914.1 - 0.089 12.0 0.0 6.1 6.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ammonium_transp PF00909.21 KIK47915.1 - 2.7e-107 358.9 26.5 3.2e-107 358.7 26.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF1269 PF06897.12 KIK47915.1 - 4.4 7.6 6.2 1.5 9.1 1.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) DUF1344 PF07076.11 KIK47917.1 - 0.0093 15.9 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1344) HET PF06985.11 KIK47918.1 - 8.5e-08 32.7 0.0 1.4e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RT_RNaseH PF17917.1 KIK47920.1 - 0.088 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KIK47921.1 - 1.8e-10 40.7 0.0 7.3e-10 38.8 0.0 1.9 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KIK47921.1 - 0.00028 21.1 0.0 0.0015 18.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 KIK47923.1 - 0.0094 16.6 0.0 0.012 16.3 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK47923.1 - 0.029 14.9 0.0 0.034 14.7 0.0 1.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 KIK47924.1 - 0.22 11.8 0.7 0.73 10.2 0.1 2.2 3 0 0 3 3 3 0 Retrotransposon gag protein HET PF06985.11 KIK47925.1 - 1.6e-14 54.5 0.1 2.2e-14 54.0 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NIF PF03031.18 KIK47926.1 - 9.6e-39 132.7 0.0 1.3e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF737 PF05300.11 KIK47926.1 - 0.048 14.0 0.1 0.28 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF737) DUF2076 PF09849.9 KIK47926.1 - 0.14 12.1 1.5 0.15 12.1 0.3 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) ATP-synt_E PF05680.12 KIK47926.1 - 1 9.7 4.5 1.1 9.6 0.4 2.3 2 0 0 2 2 2 0 ATP synthase E chain TFIIA PF03153.13 KIK47928.1 - 0.0027 17.8 3.6 0.0028 17.7 3.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF572 PF04502.13 KIK47928.1 - 0.011 15.4 16.6 0.013 15.1 16.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Asp-B-Hydro_N PF05279.11 KIK47928.1 - 9.2 6.2 23.3 13 5.8 23.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region ATP11 PF06644.11 KIK47929.1 - 3.3e-78 263.2 0.1 3.7e-78 263.0 0.1 1.0 1 0 0 1 1 1 1 ATP11 protein PI3K_C2 PF00792.24 KIK47929.1 - 0.0011 18.8 0.1 0.0022 17.9 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 NAD_binding_10 PF13460.6 KIK47930.1 - 1.9e-29 102.9 0.1 2.1e-29 102.7 0.1 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIK47930.1 - 3.5e-10 39.8 0.0 5.4e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KIK47930.1 - 4.9e-06 26.2 0.0 8.3e-06 25.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KIK47930.1 - 9.7e-06 25.9 0.0 1.6e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KIK47930.1 - 0.0007 20.0 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 KIK47930.1 - 0.13 11.7 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.19 KIK47930.1 - 0.18 10.8 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family BPL_LplA_LipB PF03099.19 KIK47931.1 - 2.1e-05 24.4 0.0 5.1e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Apolipoprotein PF01442.18 KIK47935.1 - 0.0065 16.4 2.3 0.0092 15.9 2.3 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain HisKA_3 PF07730.13 KIK47935.1 - 0.024 15.2 1.8 0.11 13.1 0.8 2.1 1 1 1 2 2 2 0 Histidine kinase DUF883 PF05957.13 KIK47935.1 - 0.13 12.9 8.1 0.69 10.6 1.6 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.18 KIK47935.1 - 0.15 12.1 5.0 0.19 11.8 5.0 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF948 PF06103.11 KIK47935.1 - 0.85 9.9 6.9 2.5 8.4 3.0 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) CtnDOT_TraJ PF07863.11 KIK47935.1 - 0.85 10.3 8.0 0.4 11.4 1.2 2.5 1 1 2 3 3 3 0 Homologues of TraJ from Bacteroides conjugative transposon YtxH PF12732.7 KIK47935.1 - 1 9.9 13.3 42 4.8 13.3 2.2 1 1 0 1 1 1 0 YtxH-like protein CsbD PF05532.12 KIK47935.1 - 3.4 7.7 20.4 1.5 8.8 15.0 2.6 2 1 0 2 2 2 0 CsbD-like BAR PF03114.18 KIK47937.1 - 2.9e-40 138.4 0.5 7.1e-40 137.2 0.5 1.6 1 1 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KIK47937.1 - 2.3e-15 55.9 0.1 4.1e-15 55.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK47937.1 - 1.4e-13 50.4 0.1 2.5e-13 49.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIK47937.1 - 1.8e-08 33.9 0.0 3.1e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Beach PF02138.18 KIK47937.1 - 0.071 12.5 1.5 0.1 12.0 0.2 1.8 2 0 0 2 2 2 0 Beige/BEACH domain SBDS PF01172.18 KIK47938.1 - 8.5e-36 121.9 1.6 1.4e-35 121.2 1.6 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 KIK47938.1 - 5.6e-34 116.6 0.9 8.8e-34 116.0 0.3 1.6 2 0 0 2 2 2 1 SBDS protein C-terminal domain Phage_TAC_5 PF08890.11 KIK47938.1 - 0.0058 16.6 0.1 0.026 14.5 0.1 2.1 1 1 0 1 1 1 1 Phage XkdN-like tail assembly chaperone protein, TAC Fe-S_biosyn PF01521.20 KIK47941.1 - 1.2e-21 77.0 0.0 1.5e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis UMP1 PF05348.11 KIK47942.1 - 3e-29 101.6 0.1 3.8e-29 101.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 SPRY PF00622.28 KIK47943.1 - 5.4e-24 84.6 0.1 9.9e-24 83.8 0.1 1.5 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 KIK47943.1 - 5.9e-18 65.2 0.0 7.9e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KIK47943.1 - 0.00093 19.1 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 LisH RdRP PF05183.12 KIK47944.1 - 9.9e-161 536.3 0.0 1.3e-160 535.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase REV PF00424.18 KIK47944.1 - 0.022 14.8 0.3 0.055 13.5 0.3 1.6 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) MFAP1 PF06991.11 KIK47945.1 - 1.7e-66 224.2 22.9 1.7e-66 224.2 22.9 2.1 3 0 0 3 3 3 1 Microfibril-associated/Pre-mRNA processing PARP PF00644.20 KIK47946.1 - 1.1e-51 175.2 0.2 2.9e-51 173.9 0.0 1.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KIK47946.1 - 1e-34 119.6 0.0 1.5e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KIK47946.1 - 5.1e-19 68.1 0.0 1.1e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 WGR domain LRS4 PF10422.9 KIK47946.1 - 0.12 12.0 3.9 0.23 11.0 3.9 1.4 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 HMG_box PF00505.19 KIK47947.1 - 2.1e-11 44.1 0.4 3.6e-11 43.3 0.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box Flagellar_rod PF05149.12 KIK47947.1 - 0.044 13.2 0.3 0.068 12.6 0.3 1.2 1 0 0 1 1 1 0 Paraflagellar rod protein HMG_box_2 PF09011.10 KIK47947.1 - 0.052 14.2 0.1 0.093 13.3 0.1 1.4 1 0 0 1 1 1 0 HMG-box domain DHO_dh PF01180.21 KIK47948.1 - 7.6e-16 58.2 0.0 1.5e-15 57.2 0.0 1.4 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase TRAPP PF04051.16 KIK47951.1 - 6.9e-41 139.4 0.0 8.4e-41 139.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PI-PLC-X PF00388.19 KIK47951.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 1 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Cullin PF00888.22 KIK47953.1 - 8.1e-05 21.4 0.0 9.7e-05 21.2 0.0 1.3 1 0 0 1 1 1 1 Cullin family US6 PF17616.2 KIK47953.1 - 0.11 12.4 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Viral unique short region 6 Phage_Mu_F PF04233.14 KIK47953.1 - 0.14 12.9 0.0 0.29 11.9 0.0 1.6 1 0 0 1 1 1 0 Phage Mu protein F like protein Arg_decarbox_C PF17944.1 KIK47953.1 - 0.21 12.2 0.8 0.51 10.9 0.1 2.0 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension Lyase_8 PF02278.18 KIK47954.1 - 1e-66 225.0 2.2 1e-66 225.0 2.2 1.8 2 0 0 2 2 2 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 KIK47954.1 - 5.5e-16 58.4 0.1 9.5e-16 57.6 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 KIK47954.1 - 1.1e-06 29.0 0.5 3.8e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain DUF3496 PF12001.8 KIK47955.1 - 0.061 13.7 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) Med2 PF11214.8 KIK47955.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 2 Atg14 PF10186.9 KIK47956.1 - 8.5e-13 48.1 0.2 1.7e-12 47.1 0.2 1.4 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 AIG1 PF04548.16 KIK47956.1 - 0.016 14.5 6.4 1.1 8.5 1.5 2.3 2 0 0 2 2 2 0 AIG1 family VPS38 PF17649.1 KIK47956.1 - 0.035 13.0 0.1 1.6 7.6 0.0 2.5 2 1 0 2 2 2 0 Vacuolar protein sorting 38 PUF PF00806.19 KIK47957.1 - 1.9e-58 191.0 11.0 1.5e-07 30.7 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Ribosomal_S14 PF00253.21 KIK47958.1 - 1.3e-13 50.4 2.6 1.4e-13 50.3 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e MMR_HSR1 PF01926.23 KIK47960.1 - 4e-12 46.2 0.1 2.3e-11 43.8 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK47960.1 - 8.8e-06 25.2 0.7 1.4e-05 24.6 0.7 1.3 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIK47960.1 - 5.1e-05 23.4 0.6 0.00072 19.6 0.4 2.7 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KIK47960.1 - 8.9e-05 22.4 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 KIK47960.1 - 0.00013 22.4 0.0 0.0002 21.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Roc PF08477.13 KIK47960.1 - 0.00024 21.3 0.0 0.00052 20.2 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KIK47960.1 - 0.00042 19.9 0.0 0.00069 19.3 0.0 1.3 1 0 0 1 1 1 1 Ras family AAA_23 PF13476.6 KIK47960.1 - 0.0094 16.5 0.0 0.015 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.17 KIK47960.1 - 0.015 15.4 0.1 0.025 14.7 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 KIK47960.1 - 0.016 15.5 0.1 0.029 14.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIK47960.1 - 0.018 15.4 0.0 0.025 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KIK47960.1 - 0.023 14.4 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 KIK47960.1 - 0.033 13.9 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KIK47960.1 - 0.039 14.4 0.0 0.079 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Gtr1_RagA PF04670.12 KIK47960.1 - 0.041 13.2 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KIK47960.1 - 0.076 12.5 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 KIK47960.1 - 0.079 12.5 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KIK47960.1 - 0.092 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Septin PF00735.18 KIK47960.1 - 0.093 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Septin Zeta_toxin PF06414.12 KIK47960.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.18 KIK47960.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family IIGP PF05049.13 KIK47960.1 - 0.18 10.8 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) HemolysinCabind PF00353.19 KIK47961.1 - 9.9e-13 47.8 2.4 0.086 12.8 0.0 8.4 4 3 3 9 9 9 5 RTX calcium-binding nonapeptide repeat (4 copies) NACHT PF05729.12 KIK47961.1 - 8.3e-12 45.3 0.1 3.1e-11 43.5 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KIK47961.1 - 8.4e-07 29.5 1.0 1.5e-06 28.7 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIK47961.1 - 0.025 14.8 0.0 0.068 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK47961.1 - 0.073 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KIK47961.1 - 0.08 13.5 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KIK47961.1 - 0.22 12.0 0.0 0.81 10.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Glyco_hydro_72 PF03198.14 KIK47963.1 - 5.7e-88 295.2 0.0 8e-88 294.7 0.0 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KIK47963.1 - 3.2e-18 66.2 3.4 9e-18 64.7 3.4 1.9 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 KIK47963.1 - 0.0056 16.1 0.0 0.0092 15.4 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RRM_1 PF00076.22 KIK47964.1 - 3.4e-13 49.2 0.0 4.9e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KIK47964.1 - 4.2e-08 32.9 2.4 7.4e-08 32.1 2.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KIK47964.1 - 0.0002 21.1 0.9 0.00048 19.9 0.9 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KIK47964.1 - 0.0016 18.4 0.2 0.0034 17.3 0.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KIK47964.1 - 0.0018 18.0 3.0 0.0043 16.7 3.0 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger RRM_3 PF08777.11 KIK47964.1 - 0.18 11.8 0.0 0.27 11.3 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif WD40 PF00400.32 KIK47965.1 - 1.5e-32 111.1 0.9 1e-05 26.2 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 KIK47965.1 - 1.4e-07 30.6 0.1 0.0024 16.6 0.0 3.4 3 1 1 4 4 4 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KIK47965.1 - 8.9e-05 22.7 0.0 6.5 7.1 0.0 5.0 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain S6OS1 PF15676.5 KIK47965.1 - 0.13 10.8 0.6 0.18 10.2 0.6 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family DivIC PF04977.15 KIK47965.1 - 0.36 10.6 1.8 0.79 9.5 1.8 1.5 1 0 0 1 1 1 0 Septum formation initiator BC10 PF06726.12 KIK47966.1 - 1.6e-11 44.2 10.2 3.1e-11 43.3 10.2 1.5 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 D5_N PF08706.11 KIK47966.1 - 0.1 12.9 0.2 0.15 12.3 0.2 1.2 1 0 0 1 1 1 0 D5 N terminal like DUF87 PF01935.17 KIK47966.1 - 0.12 12.5 0.3 0.16 12.1 0.3 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain Flu_B_NS1 PF02942.14 KIK47966.1 - 0.15 11.1 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) SYF2 PF08231.12 KIK47967.1 - 9.3e-48 162.6 3.6 1.2e-47 162.3 3.6 1.2 1 0 0 1 1 1 1 SYF2 splicing factor Cons_hypoth95 PF03602.15 KIK47967.1 - 0.066 12.8 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CS PF04969.16 KIK47968.1 - 0.00012 23.0 0.1 0.0002 22.3 0.1 1.4 1 0 0 1 1 1 1 CS domain DUF3584 PF12128.8 KIK47968.1 - 0.1 10.1 0.0 0.12 9.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Forkhead_N PF08430.12 KIK47968.1 - 3.5 8.2 28.8 7.3 7.2 28.8 1.5 1 0 0 1 1 1 0 Forkhead N-terminal region F-box-like PF12937.7 KIK47969.1 - 6.3e-05 22.8 0.4 0.00021 21.1 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK47969.1 - 0.0031 17.4 0.1 0.013 15.4 0.1 2.1 1 0 0 1 1 1 1 F-box domain HET PF06985.11 KIK47970.1 - 6.9e-24 84.9 0.0 1.2e-23 84.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.22 KIK47971.1 - 1.9e-50 172.0 0.0 2.3e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HCMV_UL124 PF17609.2 KIK47971.1 - 0.043 14.0 0.2 0.09 13.0 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function LPD13 PF18825.1 KIK47971.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 13 PNTB_4TM PF12769.7 KIK47974.1 - 2.4 8.7 7.5 1.8 9.1 4.7 2.1 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch Peptidase_S28 PF05577.12 KIK47975.1 - 3.8e-56 190.7 0.0 2.3e-55 188.1 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 KIK47975.1 - 0.00033 19.5 0.1 0.00056 18.7 0.1 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 Y_phosphatase PF00102.27 KIK47977.1 - 8.9e-48 162.9 0.7 5.2e-30 104.7 0.0 4.8 4 1 0 4 4 4 4 Protein-tyrosine phosphatase Rhodanese PF00581.20 KIK47977.1 - 0.00057 20.4 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Copper-fist PF00649.18 KIK47978.1 - 1.6e-20 72.3 3.1 1.6e-20 72.3 3.1 2.6 3 0 0 3 3 3 1 Copper fist DNA binding domain WD40 PF00400.32 KIK47980.1 - 1.8e-17 63.4 5.4 7.9e-05 23.4 0.2 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KIK47980.1 - 4.4e-07 29.2 0.0 0.014 14.4 0.0 3.0 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK47980.1 - 2.4e-06 26.5 0.0 0.00044 19.0 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KIK47980.1 - 3.9e-06 27.1 0.1 0.0001 22.5 0.1 2.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KIK47980.1 - 0.00066 19.1 0.1 0.057 12.7 0.1 2.6 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.6 KIK47980.1 - 0.002 17.7 0.3 0.0028 17.3 0.3 1.3 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 KIK47980.1 - 0.027 14.4 0.1 3.8 7.6 0.0 3.3 4 0 0 4 4 4 0 PQQ enzyme repeat RAB3GAP2_N PF14655.6 KIK47980.1 - 0.028 13.7 0.0 0.038 13.2 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Phosphoesterase PF04185.14 KIK47982.1 - 1.8e-30 106.4 4.1 8.2e-30 104.2 4.1 1.8 1 1 0 1 1 1 1 Phosphoesterase family AAA_19 PF13245.6 KIK47982.1 - 0.13 12.6 0.9 0.26 11.6 0.9 1.4 1 0 0 1 1 1 0 AAA domain PT-VENN PF04829.13 KIK47982.1 - 0.16 12.0 0.0 0.16 12.0 0.0 3.7 4 0 0 4 4 4 0 Pre-toxin domain with VENN motif BTB PF00651.31 KIK47983.1 - 0.00032 20.9 0.0 0.00062 20.0 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain PSK_trans_fac PF07704.11 KIK47983.1 - 0.13 13.1 0.2 8 7.3 0.0 2.6 2 0 0 2 2 2 0 Rv0623-like transcription factor NmrA PF05368.13 KIK47984.1 - 3.6e-16 59.4 0.0 4.4e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIK47984.1 - 7.1e-09 35.8 0.1 9.1e-09 35.5 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIK47984.1 - 5.9e-05 22.6 0.0 7.5e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIK47984.1 - 0.0027 16.9 0.1 0.0035 16.5 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KIK47984.1 - 0.0027 17.2 0.1 0.0038 16.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Mur_ligase PF01225.25 KIK47984.1 - 0.012 15.9 0.2 0.5 10.7 0.1 2.8 2 1 0 2 2 2 0 Mur ligase family, catalytic domain adh_short_C2 PF13561.6 KIK47984.1 - 0.028 14.0 0.1 0.039 13.5 0.1 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Glyco_trans_4_4 PF13579.6 KIK47984.1 - 0.064 13.7 0.2 0.74 10.2 0.2 2.4 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain DUF4774 PF15999.5 KIK47984.1 - 0.1 12.5 1.2 0.25 11.2 1.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4774) Polysacc_synt_2 PF02719.15 KIK47984.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Cu-oxidase_3 PF07732.15 KIK47985.1 - 1.6e-45 153.9 6.6 2.9e-43 146.7 1.8 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK47985.1 - 3.1e-37 127.4 4.6 4.1e-35 120.5 0.1 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KIK47985.1 - 3.9e-31 108.3 1.0 2.5e-29 102.4 0.0 3.1 3 0 0 3 3 3 1 Multicopper oxidase Glyco_trans_1_4 PF13692.6 KIK47987.1 - 8.9e-08 32.6 0.0 2.8e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KIK47987.1 - 0.0039 16.7 0.0 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIK47987.1 - 0.016 15.3 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KIK47987.1 - 0.042 14.3 0.0 0.083 13.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Nfu_N PF08712.11 KIK47988.1 - 2.2e-28 98.1 0.0 7e-28 96.5 0.0 1.8 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KIK47988.1 - 4e-27 94.2 0.1 8.4e-27 93.1 0.1 1.6 1 0 0 1 1 1 1 NifU-like domain WD40 PF00400.32 KIK47990.1 - 7.2e-44 146.9 34.2 3.9e-08 33.8 4.1 7.8 8 0 0 8 8 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK47990.1 - 8.6e-22 77.3 5.6 0.00077 19.7 0.2 6.4 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK47990.1 - 5.3e-12 45.3 0.0 0.099 11.6 0.0 6.0 2 2 4 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK47990.1 - 2.8e-10 40.4 0.2 2.5e-05 24.2 0.2 3.1 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK47990.1 - 4.5e-09 36.0 0.1 0.84 9.6 0.0 5.8 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK47990.1 - 6.3e-09 35.0 4.8 0.054 12.1 1.0 4.2 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KIK47990.1 - 0.002 17.0 3.4 11 4.7 0.1 4.1 2 2 2 4 4 4 3 Nup133 N terminal like WD40_like PF17005.5 KIK47990.1 - 0.0042 16.5 0.0 0.036 13.4 0.0 2.5 3 1 0 3 3 3 1 WD40-like domain Cytochrom_D1 PF02239.16 KIK47990.1 - 0.0089 14.6 0.1 2.1 6.8 0.0 2.8 2 1 0 2 2 2 2 Cytochrome D1 heme domain Frtz PF11768.8 KIK47990.1 - 0.019 13.3 0.0 1.1 7.4 0.0 2.2 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 KIK47990.1 - 0.021 14.2 4.5 4.4 6.5 0.2 4.1 2 2 3 5 5 4 0 Neuroblastoma-amplified sequence, N terminal PQQ PF01011.21 KIK47990.1 - 0.028 14.3 0.0 98 3.2 0.0 5.0 6 0 0 6 6 6 0 PQQ enzyme repeat Proteasome_A_N PF10584.9 KIK47990.1 - 1 9.1 4.8 22 4.8 0.0 4.6 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature WD40 PF00400.32 KIK47991.1 - 2.7e-27 94.5 18.2 7.7e-07 29.7 0.2 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK47991.1 - 1.3e-12 47.9 2.1 0.00041 20.6 0.1 4.1 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK47991.1 - 3.5e-07 29.2 0.7 0.035 12.8 0.0 3.7 3 1 0 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK47991.1 - 5.3e-06 25.6 0.0 0.4 9.6 0.0 3.7 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK47991.1 - 0.001 18.4 1.1 0.41 9.9 0.1 3.1 1 1 3 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.6 KIK47991.1 - 0.0012 18.5 0.8 0.011 15.4 0.1 1.9 1 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 KIK47991.1 - 0.0013 18.5 0.0 7.5 6.7 0.0 3.7 3 0 0 3 3 3 1 PQQ enzyme repeat Cytochrom_D1 PF02239.16 KIK47991.1 - 0.0057 15.2 1.3 0.6 8.6 0.7 2.6 1 1 2 3 3 3 2 Cytochrome D1 heme domain PQQ_3 PF13570.6 KIK47991.1 - 0.039 14.5 0.1 17 6.1 0.1 3.5 3 0 0 3 3 3 0 PQQ-like domain GSDH PF07995.11 KIK47991.1 - 0.04 13.2 0.1 1.7 7.8 0.0 2.3 2 1 0 2 2 2 0 Glucose / Sorbosone dehydrogenase Frtz PF11768.8 KIK47991.1 - 0.058 11.7 0.0 0.082 11.2 0.0 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 KIK47991.1 - 0.067 13.2 0.1 13 5.8 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 KIK47991.1 - 0.099 11.7 0.0 1.7 7.6 0.0 2.0 1 1 1 2 2 2 0 Coatomer WD associated region DUF3486 PF11985.8 KIK47994.1 - 0.0076 16.7 3.3 0.01 16.3 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3486) Cluap1 PF10234.9 KIK47994.1 - 0.012 15.0 2.3 0.014 14.8 2.3 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF3972 PF13118.6 KIK47994.1 - 0.014 15.8 3.1 0.018 15.5 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) Rep_trans PF02486.19 KIK47994.1 - 0.061 13.0 2.4 0.088 12.5 2.4 1.2 1 0 0 1 1 1 0 Replication initiation factor Collectrin PF16959.5 KIK47994.1 - 0.09 12.5 0.9 0.17 11.6 0.9 1.5 1 0 0 1 1 1 0 Renal amino acid transporter GTSE1_N PF15259.6 KIK47994.1 - 0.29 11.3 3.2 0.53 10.5 3.2 1.4 1 1 0 1 1 1 0 G-2 and S-phase expressed 1 RasGEF PF00617.19 KIK47995.1 - 1.9e-53 181.3 0.8 3.5e-53 180.4 0.8 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KIK47995.1 - 4.4e-19 68.6 0.0 1.1e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif WW PF00397.26 KIK47995.1 - 0.093 12.8 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 WW domain LRR19-TM PF15176.6 KIK47996.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Ribosomal_L23eN PF03939.13 KIK47997.1 - 6.6e-25 87.1 10.3 1.4e-24 86.1 10.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KIK47997.1 - 1.7e-15 57.2 2.4 1.7e-15 57.2 2.4 2.3 2 1 0 2 2 2 1 Ribosomal protein L23 DUF5451 PF17532.2 KIK47997.1 - 0.002 18.4 1.1 0.0025 18.1 1.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5451) Terminase_3C PF17288.2 KIK47997.1 - 0.042 14.2 0.3 0.051 14.0 0.3 1.2 1 0 0 1 1 1 0 Terminase RNAseH like domain SMC_N PF02463.19 KIK47998.1 - 2e-32 112.4 13.5 3.8e-32 111.5 13.6 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KIK47998.1 - 8.5e-25 87.3 0.0 3.7e-24 85.3 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KIK47998.1 - 2.7e-14 54.1 50.5 1.4e-08 35.5 42.6 4.4 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KIK47998.1 - 3.5e-08 33.5 14.3 3.5e-08 33.5 14.3 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KIK47998.1 - 2.6e-06 27.5 0.2 9.9e-06 25.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIK47998.1 - 0.0087 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KIK47998.1 - 0.018 14.4 0.3 0.15 11.4 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family Med4 PF10018.9 KIK47998.1 - 0.04 13.6 0.5 0.04 13.6 0.5 5.2 3 2 1 4 4 3 0 Vitamin-D-receptor interacting Mediator subunit 4 Filo_VP35 PF02097.15 KIK47998.1 - 0.049 12.7 1.6 0.6 9.1 0.2 2.4 1 1 0 2 2 2 0 Filoviridae VP35 MscS_porin PF12795.7 KIK47998.1 - 0.41 10.2 61.5 0.34 10.4 7.5 5.0 3 2 1 4 4 4 0 Mechanosensitive ion channel porin domain PTS_IIA PF02255.16 KIK47998.1 - 0.58 10.2 0.0 0.58 10.2 0.0 4.0 4 0 0 4 4 4 0 PTS system, Lactose/Cellobiose specific IIA subunit ABC_tran PF00005.27 KIK47998.1 - 0.68 10.5 0.0 0.68 10.5 0.0 4.1 3 2 0 3 3 2 0 ABC transporter DUF87 PF01935.17 KIK47998.1 - 1 9.4 0.0 1 9.4 0.0 4.1 3 1 0 4 4 4 0 Helicase HerA, central domain AAA_13 PF13166.6 KIK47998.1 - 1.7 7.2 44.1 1.6 7.2 3.8 4.6 3 2 0 4 4 4 0 AAA domain DUF3854 PF12965.7 KIK47998.1 - 9 6.3 7.8 0.93 9.5 0.2 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3854) ADH_N PF08240.12 KIK47999.1 - 3e-17 62.5 0.6 5.6e-17 61.6 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK47999.1 - 4e-11 43.0 0.2 8e-11 42.0 0.2 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 KIK47999.1 - 0.067 12.8 0.2 0.1 12.2 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Peptidase_M20 PF01546.28 KIK48001.1 - 7.5e-28 97.7 0.0 1.1e-27 97.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 KIK48001.1 - 9.5e-11 42.1 20.5 0.0043 17.9 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat M20_dimer PF07687.14 KIK48001.1 - 3.5e-10 39.8 0.0 6.7e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain ANAPC4_WD40 PF12894.7 KIK48001.1 - 0.0008 19.7 0.1 0.33 11.3 0.0 3.3 2 2 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KIK48001.1 - 0.077 13.5 0.0 0.58 10.7 0.0 2.6 1 0 0 1 1 1 0 PQQ-like domain RPAP3_C PF13877.6 KIK48002.1 - 5.4e-17 62.1 0.5 9.8e-17 61.3 0.3 1.5 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 KIK48002.1 - 3e-12 45.8 2.7 3.6e-05 23.4 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK48002.1 - 2.3e-11 42.9 0.9 0.0053 16.8 0.1 3.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIK48002.1 - 3.7e-09 37.1 0.1 0.00026 21.6 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIK48002.1 - 1.1e-07 31.4 0.1 3.6e-05 23.4 0.1 2.5 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.6 KIK48002.1 - 1.4e-07 31.9 0.1 1.6e-06 28.5 0.0 2.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK48002.1 - 6.4e-05 22.7 0.0 0.16 12.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIK48002.1 - 8.4e-05 22.7 0.1 0.1 13.0 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK48002.1 - 0.0017 18.4 0.1 0.26 11.6 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIK48002.1 - 0.0028 17.9 0.2 1.1 9.5 0.0 3.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK48002.1 - 0.0032 18.1 0.2 2.4 9.2 0.1 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIK48002.1 - 0.008 16.3 0.0 0.33 11.1 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat CRAL_TRIO PF00650.20 KIK48004.1 - 2.5e-25 89.1 0.0 3.6e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIK48004.1 - 9.4e-09 35.3 0.2 2e-08 34.3 0.2 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Nipped-B_C PF12830.7 KIK48005.1 - 3.8e-55 186.8 3.7 2.2e-54 184.3 3.7 2.5 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KIK48005.1 - 8.7e-14 51.5 1.8 2.8e-13 49.9 0.8 2.5 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 KIK48005.1 - 5.3e-05 23.1 1.1 0.63 10.4 0.0 4.2 3 0 0 3 3 3 2 HEAT repeat Cnd1 PF12717.7 KIK48005.1 - 0.00065 19.8 0.0 0.0032 17.5 0.0 2.3 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIK48005.1 - 0.0075 16.6 0.7 0.0075 16.6 0.7 4.6 4 2 1 5 5 5 2 HEAT repeats M11L PF11099.8 KIK48005.1 - 0.051 13.9 0.2 17 5.6 0.0 2.6 2 0 0 2 2 2 0 Apoptosis regulator M11L like HEAT_EZ PF13513.6 KIK48005.1 - 0.078 13.5 1.6 1.5 9.4 0.2 3.8 2 1 1 3 3 3 0 HEAT-like repeat RIBIOP_C PF04950.12 KIK48006.1 - 2.1e-90 303.1 0.0 2.1e-90 303.1 0.0 2.0 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KIK48006.1 - 4.9e-30 103.4 0.4 1.6e-29 101.8 0.0 2.1 2 0 0 2 2 1 1 AARP2CN (NUC121) domain AAA_16 PF13191.6 KIK48006.1 - 2.1e-05 25.0 0.3 8.2e-05 23.0 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK48006.1 - 3.2e-05 24.2 0.0 8.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KIK48006.1 - 0.00012 21.7 0.0 0.052 13.1 0.0 2.5 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 KIK48006.1 - 0.00046 20.4 1.3 0.0013 18.9 0.0 2.3 2 1 0 2 2 1 1 AAA domain NACHT PF05729.12 KIK48006.1 - 0.00098 19.1 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 KIK48006.1 - 0.0012 19.3 0.0 0.0039 17.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KIK48006.1 - 0.0014 18.7 0.0 0.0042 17.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KIK48006.1 - 0.003 18.1 0.0 0.003 18.1 0.0 2.3 2 0 0 2 2 1 1 ABC transporter PduV-EutP PF10662.9 KIK48006.1 - 0.0033 17.2 0.0 0.013 15.3 0.0 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 KIK48006.1 - 0.0039 17.7 2.5 0.0042 17.6 0.1 2.4 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.22 KIK48006.1 - 0.005 16.1 0.0 0.0094 15.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 KIK48006.1 - 0.0062 16.9 0.0 0.017 15.5 0.0 1.8 1 0 0 1 1 1 1 RNA helicase cobW PF02492.19 KIK48006.1 - 0.016 14.8 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KIK48006.1 - 0.019 15.2 0.1 0.019 15.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 KIK48006.1 - 0.024 14.5 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 KIK48006.1 - 0.026 14.4 0.2 0.064 13.2 0.2 1.7 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 KIK48006.1 - 0.03 14.1 0.1 0.03 14.1 0.1 1.6 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.6 KIK48006.1 - 0.031 14.6 0.1 0.076 13.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KIK48006.1 - 0.035 13.7 0.0 0.09 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KIK48006.1 - 0.05 13.5 0.0 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_14 PF13173.6 KIK48006.1 - 0.06 13.4 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KIK48006.1 - 0.06 13.8 0.1 0.06 13.8 0.1 2.8 2 0 0 2 2 1 0 AAA domain Roc PF08477.13 KIK48006.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KIK48006.1 - 0.067 12.9 0.1 0.067 12.9 0.1 2.1 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.14 KIK48006.1 - 0.077 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KIK48006.1 - 0.14 12.1 1.8 0.2 11.6 0.0 2.0 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea SRP54 PF00448.22 KIK48006.1 - 0.14 11.8 0.1 0.14 11.8 0.1 1.9 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 KIK48006.1 - 0.67 10.4 8.9 4.5 7.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain Rtf2 PF04641.12 KIK48006.1 - 2.2 7.6 14.1 0.0074 15.7 4.2 1.9 2 0 0 2 2 1 0 Rtf2 RING-finger AAA_11 PF13086.6 KIK48006.1 - 2.9 7.6 13.4 0.71 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KIK48006.1 - 6.4 6.8 8.5 6.8 6.7 0.1 3.1 3 0 0 3 3 2 0 Dynamin family Cep57_MT_bd PF06657.13 KIK48007.1 - 7e-21 74.5 0.4 7e-21 74.5 0.4 4.9 3 1 2 5 5 5 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 KIK48007.1 - 4.5e-08 33.1 7.0 4.5e-08 33.1 7.0 3.4 3 0 0 3 3 3 1 Centrosome localisation domain of PPC89 Herpes_UL6 PF01763.16 KIK48007.1 - 0.0075 14.8 0.5 0.0075 14.8 0.5 1.8 1 1 1 2 2 2 1 Herpesvirus UL6 like DUF3461 PF11944.8 KIK48007.1 - 0.095 12.8 2.2 0.42 10.8 2.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) Pox_A_type_inc PF04508.12 KIK48007.1 - 0.69 9.9 6.6 0.53 10.2 1.0 3.6 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat IZUMO PF15005.6 KIK48007.1 - 6.3 7.3 6.3 4.9 7.7 3.1 2.4 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated zf-rbx1 PF12678.7 KIK48008.1 - 2e-24 85.6 12.7 2.9e-24 85.1 12.7 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KIK48008.1 - 6.1e-17 61.5 9.7 7.9e-17 61.1 9.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KIK48008.1 - 4.7e-06 26.8 14.8 0.00018 21.8 14.8 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK48008.1 - 3.9e-05 23.4 3.5 3.9e-05 23.4 3.5 2.5 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK48008.1 - 0.00087 19.1 12.0 0.023 14.6 12.0 2.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK48008.1 - 0.18 11.7 10.6 0.66 9.9 4.4 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK48008.1 - 0.31 11.1 7.6 1.1 9.3 7.6 2.0 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 KIK48008.1 - 0.4 10.9 9.6 2.3 8.5 9.9 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KIK48008.1 - 0.61 9.7 14.3 0.11 12.1 4.3 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KIK48008.1 - 1.8 8.4 17.2 1.1e+02 2.7 17.2 2.5 1 1 0 1 1 1 0 RING-like zinc finger RRM_1 PF00076.22 KIK48009.1 - 1.2e-12 47.5 0.0 2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIK48009.1 - 3.7e-06 26.7 0.0 9.2e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KIK48009.1 - 0.0072 16.3 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KIK48009.1 - 0.08 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif DUF4523 PF15023.6 KIK48009.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Methyltransf_11 PF08241.12 KIK48010.1 - 2.6e-17 63.2 0.0 4.7e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK48010.1 - 1.3e-16 60.8 0.0 2e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK48010.1 - 9.6e-14 51.9 0.0 1.9e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK48010.1 - 4.2e-12 46.2 0.0 6e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK48010.1 - 2.5e-11 44.2 0.0 4e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK48010.1 - 1.2e-10 41.1 0.0 1.2e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KIK48010.1 - 1.9e-08 34.0 0.0 3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KIK48010.1 - 6.6e-06 26.0 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 KIK48010.1 - 1.4e-05 24.8 0.0 2.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KIK48010.1 - 0.00086 19.3 0.1 0.0015 18.5 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KIK48010.1 - 0.0012 18.3 0.0 0.0018 17.6 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase GCD14 PF08704.10 KIK48010.1 - 0.016 14.9 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_7 PF03492.15 KIK48010.1 - 0.033 13.4 0.0 3.8 6.6 0.0 2.6 3 0 0 3 3 3 0 SAM dependent carboxyl methyltransferase FtsJ PF01728.19 KIK48010.1 - 0.093 12.8 0.2 0.65 10.1 0.2 2.1 1 1 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 KIK48010.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) LRR_4 PF12799.7 KIK48011.1 - 2.8e-26 91.2 37.9 9e-05 22.8 2.2 8.2 6 1 1 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIK48011.1 - 1.5e-22 79.1 35.1 2.5e-06 27.2 2.4 6.5 5 1 0 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 KIK48011.1 - 2e-18 66.5 13.2 2.7e-07 30.3 0.5 5.2 3 1 2 5 5 5 5 Leucine-rich repeat DUF2379 PF09543.10 KIK48011.1 - 0.13 12.5 0.4 0.35 11.1 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) FGAR-AT_N PF18076.1 KIK48011.1 - 0.14 12.2 0.0 0.43 10.6 0.0 1.8 1 0 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase N-terminal LRR_6 PF13516.6 KIK48011.1 - 3.6 7.9 24.3 1.7 8.9 0.4 7.7 9 0 0 9 9 9 0 Leucine Rich repeat LRR_1 PF00560.33 KIK48011.1 - 5.1 8.0 34.8 4.8 8.1 0.4 8.2 7 3 0 7 7 7 0 Leucine Rich Repeat DGF-1_C PF11040.8 KIK48011.1 - 5.3 7.1 10.3 2.4 8.2 0.1 4.6 4 0 0 4 4 4 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Homeobox_KN PF05920.11 KIK48012.1 - 7.5e-20 70.6 0.7 8.2e-19 67.2 0.1 2.9 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KIK48012.1 - 2.1e-05 24.3 0.1 5.5e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 Homeodomain Methyltransf_32 PF13679.6 KIK48015.1 - 1.1e-22 80.7 0.1 5.5e-22 78.4 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK48015.1 - 0.0056 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK48015.1 - 0.019 15.7 0.0 0.042 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KIK48015.1 - 0.069 13.8 0.0 0.14 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HVSL PF09749.9 KIK48016.1 - 4.3e-43 147.5 0.0 7.7e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 KIK48016.1 - 0.00014 21.8 0.1 0.00027 20.9 0.1 1.4 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily DUF3368 PF11848.8 KIK48016.1 - 0.07 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) cobW PF02492.19 KIK48017.1 - 5.9e-31 107.4 0.0 7.3e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KIK48017.1 - 0.0037 17.3 0.0 0.0081 16.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 KIK48017.1 - 0.0051 15.8 0.3 0.4 9.6 0.0 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB TIP49 PF06068.13 KIK48017.1 - 0.022 14.0 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain CbiA PF01656.23 KIK48017.1 - 0.064 13.3 0.2 0.26 11.4 0.2 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 KIK48017.1 - 0.067 13.7 0.0 0.092 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIK48017.1 - 0.071 13.6 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 KIK48017.1 - 0.088 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KIK48017.1 - 0.088 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.12 KIK48017.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein T2SSE PF00437.20 KIK48017.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KIK48017.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ResIII PF04851.15 KIK48017.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 KIK48017.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Roc PF08477.13 KIK48017.1 - 0.13 12.4 0.0 0.84 9.9 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Iwr1 PF08574.10 KIK48018.1 - 1.4e-12 48.4 11.1 1.4e-12 48.4 11.1 2.8 3 0 0 3 3 3 1 Transcription factor Iwr1 His_Phos_2 PF00328.22 KIK48019.1 - 0.056 12.8 0.6 9.6 5.4 0.3 2.6 2 1 1 3 3 3 0 Histidine phosphatase superfamily (branch 2) HCO3_cotransp PF00955.21 KIK48020.1 - 4.5e-66 223.7 12.7 1.8e-33 116.1 6.6 3.0 2 1 1 3 3 3 3 HCO3- transporter family Abhydrolase_6 PF12697.7 KIK48022.1 - 9.9e-13 49.2 1.5 9.9e-13 49.2 1.5 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK48022.1 - 2.9e-12 46.4 0.1 2.1e-08 33.8 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KIK48022.1 - 6e-08 32.8 0.0 8.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KIK48022.1 - 3.3e-07 30.2 0.2 6.7e-06 25.9 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK48022.1 - 0.064 12.7 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 KIK48022.1 - 0.082 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF818 PF05677.12 KIK48022.1 - 0.24 10.3 0.0 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DUF202 PF02656.15 KIK48024.1 - 7.7e-19 67.9 0.3 7.7e-19 67.9 0.3 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) RRM_1 PF00076.22 KIK48025.1 - 4e-06 26.6 0.0 0.00032 20.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIK48025.1 - 0.035 14.0 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif F-box-like PF12937.7 KIK48028.1 - 0.075 12.9 0.1 0.24 11.3 0.1 1.9 1 0 0 1 1 1 0 F-box-like Glyco_hydro_cc PF11790.8 KIK48030.1 - 6.9e-36 124.0 0.1 8.1e-36 123.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core MFS_1 PF07690.16 KIK48031.1 - 3.1e-45 154.7 23.0 3.3e-45 154.5 22.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK48031.1 - 7.4e-15 54.8 17.2 1e-12 47.7 0.5 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 KIK48031.1 - 4.7e-06 25.2 5.4 8.9e-06 24.3 1.8 2.6 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family WBP-1 PF11669.8 KIK48031.1 - 0.062 13.9 0.1 0.79 10.4 0.0 2.6 3 0 0 3 3 3 0 WW domain-binding protein 1 ETF PF01012.21 KIK48032.1 - 7e-40 136.8 1.9 9e-40 136.5 1.9 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain acVLRF1 PF18859.1 KIK48032.1 - 0.0079 16.5 0.1 3.7 7.8 0.2 2.4 2 1 0 2 2 2 2 Actinobacteria/chloroflexi VLRF1 release factor zf-RING_2 PF13639.6 KIK48033.1 - 6e-13 48.9 3.7 1e-12 48.2 3.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KIK48033.1 - 9.5e-09 34.9 1.0 1.8e-08 33.9 1.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KIK48033.1 - 5.6e-08 32.5 3.7 9.3e-08 31.8 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIK48033.1 - 1.2e-07 31.9 4.8 2.4e-07 30.9 4.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KIK48033.1 - 1.2e-07 31.5 1.9 1.9e-07 30.8 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK48033.1 - 8e-07 28.9 2.1 1.3e-06 28.3 2.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KIK48033.1 - 5e-05 23.1 1.9 8.6e-05 22.3 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KIK48033.1 - 9.6e-05 22.4 1.9 0.0002 21.4 1.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KIK48033.1 - 0.00099 18.9 2.4 0.0018 18.1 2.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KIK48033.1 - 0.0017 18.3 3.6 0.0035 17.3 3.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KIK48033.1 - 0.0077 15.8 2.1 0.014 15.0 2.1 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KIK48033.1 - 0.059 13.2 4.3 0.11 12.3 4.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KIK48033.1 - 0.095 13.0 2.7 0.18 12.1 2.7 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 KIK48033.1 - 0.21 11.7 3.3 0.4 10.9 3.3 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_5 PF17121.5 KIK48033.1 - 0.45 10.4 3.4 0.48 10.4 2.4 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KIK48033.1 - 0.84 9.9 3.7 2.2 8.5 3.7 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Ran_BP1 PF00638.18 KIK48037.1 - 1.3e-16 61.0 0.0 2e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain Nucleo_P87 PF07267.11 KIK48037.1 - 0.64 8.8 2.2 1 8.1 2.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FIST PF08495.10 KIK48038.1 - 0.00038 20.5 0.0 0.0009 19.3 0.0 1.8 1 1 0 1 1 1 1 FIST N domain MFS_1 PF07690.16 KIK48039.1 - 5e-49 167.1 14.0 5e-49 167.1 14.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK48039.1 - 2.9e-10 39.6 26.6 1.4e-09 37.4 10.9 3.1 2 1 0 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 KIK48039.1 - 1.1e-05 24.0 0.6 7.3e-05 21.2 0.1 2.5 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KIK48039.1 - 0.00031 19.7 0.4 0.00031 19.7 0.4 3.1 2 1 1 3 3 3 1 MFS_1 like family EptA_B_N PF08019.12 KIK48039.1 - 0.48 10.3 11.8 0.16 11.8 1.0 4.0 3 1 1 4 4 4 0 Phosphoethanolamine transferase EptA/EptB DNA_pol_A_exo1 PF01612.20 KIK48040.1 - 2.6e-43 147.8 0.0 4.2e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KIK48040.1 - 3.7e-19 69.2 0.0 1.8e-18 67.0 0.0 2.3 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 KIK48040.1 - 5e-11 42.4 0.1 1.6e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 HRDC domain Pkinase PF00069.25 KIK48043.1 - 3.7e-69 233.0 0.0 5e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK48043.1 - 6.4e-41 140.3 0.0 8.8e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK48043.1 - 6.8e-06 25.6 0.0 1.7e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KIK48043.1 - 0.0079 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIK48043.1 - 0.046 13.3 0.0 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KIK48043.1 - 0.067 13.1 0.1 3.2 7.6 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Mucin PF01456.17 KIK48043.1 - 0.43 10.6 3.2 0.63 10.0 3.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Peptidase_M16 PF00675.20 KIK48045.1 - 6.1e-54 182.0 1.2 1e-53 181.3 0.5 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KIK48045.1 - 1.6e-39 135.8 0.0 1.7e-37 129.2 0.0 2.6 3 0 0 3 3 3 2 Peptidase M16 inactive domain Mit_ribos_Mrp51 PF11709.8 KIK48045.1 - 0.037 13.6 0.1 0.064 12.8 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit CoA_transf_3 PF02515.17 KIK48046.1 - 1e-46 159.8 0.3 1.9e-42 145.7 0.0 3.2 2 2 0 2 2 2 2 CoA-transferase family III Pectinesterase PF01095.19 KIK48047.1 - 1.7e-36 125.5 1.9 2.4e-35 121.7 1.9 2.0 1 1 0 1 1 1 1 Pectinesterase Bradykinin PF06753.12 KIK48047.1 - 0.012 15.3 0.1 0.025 14.3 0.1 1.5 1 0 0 1 1 1 0 Bradykinin Pkinase PF00069.25 KIK48054.1 - 4.1e-72 242.7 0.0 7.6e-72 241.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK48054.1 - 1e-50 172.5 0.0 2.5e-50 171.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Arm PF00514.23 KIK48054.1 - 0.00034 20.6 1.0 24 5.2 0.0 6.1 5 2 2 7 7 7 1 Armadillo/beta-catenin-like repeat Pkinase_fungal PF17667.1 KIK48054.1 - 0.0011 17.8 0.0 0.0018 17.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIK48054.1 - 0.0026 17.1 0.2 0.069 12.5 0.0 2.7 3 0 0 3 3 3 1 Kinase-like TnpB_IS66 PF05717.13 KIK48054.1 - 0.18 11.7 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 IS66 Orf2 like protein Ribosomal_L5_C PF00673.21 KIK48055.1 - 5.5e-27 93.8 0.0 7.6e-27 93.3 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KIK48055.1 - 0.00035 20.9 0.1 0.00073 19.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Calmodulin_bind PF07887.11 KIK48055.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Calmodulin binding protein-like Peptidase_M64 PF09471.10 KIK48057.1 - 3.7e-34 118.5 0.0 1.3e-33 116.6 0.0 1.8 1 1 0 1 1 1 1 IgA Peptidase M64 Phosducin PF02114.16 KIK48058.1 - 1.5e-09 37.2 0.0 2.7e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Phosducin Aminotran_5 PF00266.19 KIK48059.1 - 1.1e-15 57.5 0.0 1.6e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KIK48059.1 - 1.9e-08 34.0 0.2 3.3e-08 33.3 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KIK48059.1 - 0.00046 19.5 0.0 0.00077 18.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II MIF4G PF02854.19 KIK48060.1 - 0.021 14.5 0.0 0.021 14.5 0.0 1.1 1 0 0 1 1 1 0 MIF4G domain Ribosomal_L1 PF00687.21 KIK48061.1 - 4.9e-59 199.5 1.1 9e-59 198.6 1.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Hydrolase_4 PF12146.8 KIK48062.1 - 3.2e-08 33.2 1.1 3e-07 30.0 1.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIK48062.1 - 9.3e-07 29.7 0.6 1.7e-06 28.8 0.6 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK48062.1 - 9.7e-06 25.4 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.10 KIK48062.1 - 2.7e-05 23.4 0.1 6.3e-05 22.2 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.21 KIK48062.1 - 3.2e-05 23.5 0.2 6.1e-05 22.6 0.2 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF915 PF06028.11 KIK48062.1 - 0.0018 17.6 0.1 0.0071 15.7 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) ADH_zinc_N PF00107.26 KIK48064.1 - 2.7e-29 101.8 0.1 4.7e-29 101.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIK48064.1 - 1.4e-14 55.3 0.0 2.8e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIK48064.1 - 5.9e-10 39.0 0.2 3.7e-09 36.4 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain HupF_HypC PF01455.18 KIK48064.1 - 0.065 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 HupF/HypC family Fimbrial PF00419.20 KIK48064.1 - 0.072 13.4 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Fimbrial protein Dynamin_N PF00350.23 KIK48065.1 - 2.8e-18 66.6 0.1 8.7e-18 64.9 0.1 1.9 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KIK48065.1 - 8.2e-12 45.2 0.1 2.9e-11 43.4 0.1 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIK48065.1 - 2.7e-07 30.3 1.0 2.6e-06 27.1 1.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIK48065.1 - 0.002 18.0 0.7 0.43 10.5 0.4 2.8 2 1 0 2 2 2 1 RsgA GTPase cobW PF02492.19 KIK48065.1 - 0.0029 17.2 0.1 0.49 10.0 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KIK48065.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.13 KIK48065.1 - 0.052 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 KIK48065.1 - 0.058 13.6 0.0 1.1 9.4 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KIK48065.1 - 0.088 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Septin Abhydrolase_6 PF12697.7 KIK48066.1 - 0.0018 18.9 0.0 0.0035 18.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 KIK48066.1 - 0.0021 18.0 0.0 0.003 17.4 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 KIK48066.1 - 0.0049 16.4 0.0 0.013 15.0 0.0 1.6 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 KIK48066.1 - 0.0062 16.2 0.1 0.031 13.9 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KIK48066.1 - 0.0085 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein FANCA_interact PF15751.5 KIK48066.1 - 0.42 11.1 8.5 0.25 11.8 1.7 2.5 1 1 0 2 2 2 0 FAAP20 FANCA interaction domain eIF2_C PF09173.11 KIK48067.1 - 1e-34 118.7 0.4 2.4e-34 117.4 0.4 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KIK48067.1 - 5.4e-21 75.0 1.5 9.6e-20 71.0 1.5 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KIK48067.1 - 1.7e-11 44.4 1.7 2.7e-11 43.7 0.4 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KIK48067.1 - 0.0023 17.9 0.9 0.039 13.9 0.2 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KIK48067.1 - 0.015 15.3 1.5 0.024 14.6 0.2 2.0 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KIK48067.1 - 0.018 15.1 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dak1_2 PF13684.6 KIK48067.1 - 0.039 13.0 0.2 0.061 12.4 0.2 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Asp PF00026.23 KIK48069.1 - 4e-32 111.9 14.5 1.3e-31 110.3 14.5 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK48069.1 - 8.7e-07 29.3 8.8 0.00012 22.3 0.1 3.0 2 2 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK48069.1 - 0.053 14.2 3.2 0.17 12.6 0.4 2.6 2 0 0 2 2 2 0 Aspartyl protease ALMS_repeat PF18727.1 KIK48069.1 - 0.31 11.0 3.1 1.1 9.3 0.0 3.1 2 1 1 3 3 3 0 Alstrom syndrome repeat WD40 PF00400.32 KIK48070.1 - 8.6e-41 137.2 30.1 2e-07 31.6 0.7 7.9 8 0 0 8 8 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK48070.1 - 1e-17 64.2 4.2 0.0013 19.0 0.1 6.1 2 2 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIK48070.1 - 3.3e-09 36.5 0.0 0.00013 21.4 0.0 2.8 2 1 1 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 KIK48070.1 - 5.4e-08 32.2 0.6 0.41 9.5 0.0 6.0 1 1 5 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK48070.1 - 4.5e-07 29.5 1.1 0.062 12.6 0.1 4.7 2 2 3 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KIK48070.1 - 1.4e-05 23.9 2.4 0.22 10.2 0.2 4.1 3 2 0 3 3 3 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KIK48070.1 - 0.0004 19.4 3.1 0.0069 15.4 0.9 2.8 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain PD40 PF07676.12 KIK48070.1 - 0.00045 20.1 1.3 19 5.4 0.0 5.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KIK48070.1 - 0.0077 14.8 0.8 0.2 10.2 0.1 2.4 1 1 1 2 2 2 1 Cytochrome D1 heme domain DUF5570 PF17731.1 KIK48070.1 - 0.019 15.1 4.4 1.4 9.1 0.0 4.5 4 2 2 6 6 6 0 Family of unknown function (DUF5570) MAGE_N PF12440.8 KIK48070.1 - 0.055 14.2 15.1 0.082 13.6 12.8 2.2 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Arena_nucleocap PF00843.17 KIK48070.1 - 0.32 9.8 2.6 5.9 5.7 0.1 3.2 2 1 2 4 4 4 0 Arenavirus nucleocapsid N-terminal domain adh_short PF00106.25 KIK48072.1 - 1.6e-30 106.1 0.0 6.9e-29 100.7 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK48072.1 - 1.1e-19 70.9 0.0 5e-18 65.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK48072.1 - 3.7e-07 30.2 0.0 6.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK48072.1 - 2.6e-06 27.1 0.1 5.1e-06 26.1 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KIK48072.1 - 0.0047 17.0 0.1 0.0088 16.1 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 KIK48072.1 - 0.041 13.0 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KIK48072.1 - 0.077 12.4 0.0 0.33 10.3 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 KIK48072.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RNA_pol_Rpb4 PF03874.16 KIK48073.1 - 2.7e-19 69.7 0.1 4e-19 69.1 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Glyco_hydro_16 PF00722.21 KIK48074.1 - 0.00024 20.6 0.2 0.00049 19.6 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF4624 PF15417.6 KIK48074.1 - 0.028 14.2 0.5 0.061 13.1 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4624) adh_short PF00106.25 KIK48075.1 - 2.5e-24 85.8 0.0 5.3e-15 55.4 0.0 2.7 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIK48075.1 - 5.3e-22 78.5 0.1 5.9e-10 39.1 0.0 3.6 2 2 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK48075.1 - 0.068 13.1 0.0 0.44 10.4 0.0 2.0 2 0 0 2 2 2 0 KR domain SAM_2 PF07647.17 KIK48077.1 - 3.5e-08 33.4 0.0 3.4e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KIK48077.1 - 0.00051 20.4 0.1 0.0017 18.7 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF1281 PF06924.11 KIK48077.1 - 0.025 14.1 0.4 0.053 13.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1281) DUF4508 PF14969.6 KIK48077.1 - 0.052 13.8 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) tRNA_lig_CPD PF08302.11 KIK48077.1 - 0.14 11.6 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain adh_short PF00106.25 KIK48078.1 - 1.2e-41 142.3 0.5 1.7e-41 141.9 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK48078.1 - 1e-31 110.3 0.3 1.4e-31 109.9 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK48078.1 - 2.4e-06 27.6 0.2 4.4e-06 26.7 0.2 1.4 1 0 0 1 1 1 1 KR domain DUF3012 PF11216.8 KIK48078.1 - 0.054 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) ELFV_dehydrog PF00208.21 KIK48079.1 - 3.1e-54 184.3 0.0 4.2e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KIK48079.1 - 6e-17 60.6 0.0 3.3e-11 41.5 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase Flavoprotein PF02441.19 KIK48080.1 - 2.1e-51 173.8 0.1 2.5e-51 173.6 0.1 1.0 1 0 0 1 1 1 1 Flavoprotein Prenyltrans PF00432.21 KIK48081.1 - 7e-39 131.3 12.1 2.9e-09 36.5 0.4 5.6 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KIK48081.1 - 0.00011 21.4 0.0 0.059 12.5 0.0 2.9 3 0 0 3 3 3 2 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 KIK48081.1 - 0.0053 15.8 0.2 0.13 11.3 0.1 2.4 1 1 1 2 2 2 1 A-macroglobulin TED domain BIR PF00653.21 KIK48081.1 - 0.038 14.7 0.3 0.13 12.9 0.3 1.9 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain DZR PF12773.7 KIK48081.1 - 0.11 12.5 1.4 0.78 9.8 0.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon DUF5375 PF17345.2 KIK48082.1 - 0.043 13.7 0.1 0.61 10.0 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5375) MIF4G PF02854.19 KIK48082.1 - 0.14 11.8 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 MIF4G domain EB PF01683.18 KIK48083.1 - 0.2 12.0 5.9 0.52 10.6 5.9 1.7 1 0 0 1 1 1 0 EB module ELFV_dehydrog PF00208.21 KIK48084.1 - 1.6e-56 191.8 0.0 2.1e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KIK48084.1 - 2.4e-16 58.6 0.0 2.7e-10 38.5 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase YjcZ PF13990.6 KIK48088.1 - 0.15 11.4 0.1 0.16 11.3 0.1 1.0 1 0 0 1 1 1 0 YjcZ-like protein Ribosomal_L35p PF01632.19 KIK48089.1 - 1.8e-17 63.6 5.9 2.3e-17 63.2 5.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L35 APOBEC1 PF18769.1 KIK48091.1 - 0.05 13.9 0.1 0.082 13.2 0.1 1.6 1 1 0 1 1 1 0 APOBEC1 Hva1_TUDOR PF11160.8 KIK48092.1 - 6.1e-09 35.9 0.5 5.7e-07 29.6 0.5 2.0 1 1 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain DUF1918 PF08940.11 KIK48092.1 - 0.0017 17.9 0.1 0.0021 17.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1918) zf-AN1 PF01428.16 KIK48093.1 - 1.2e-13 50.9 31.0 4.7e-11 42.7 8.6 2.7 3 0 0 3 3 3 2 AN1-like Zinc finger ENTH PF01417.20 KIK48095.1 - 3e-44 150.1 0.1 4.3e-44 149.5 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KIK48095.1 - 0.00084 18.4 0.1 0.0012 18.0 0.1 1.2 1 0 0 1 1 1 1 ANTH domain DNA_pol_B_thumb PF14791.6 KIK48096.1 - 2.9e-12 46.6 0.0 8.8e-12 45.0 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 KIK48096.1 - 5.1e-11 42.8 0.0 1.4e-10 41.4 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 KIK48096.1 - 4.2e-08 32.9 0.0 8e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 KIK48096.1 - 2.4e-05 24.8 0.0 5.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain IMS_HHH PF11798.8 KIK48096.1 - 0.017 15.4 0.0 0.039 14.3 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif Cdd1 PF11731.8 KIK48096.1 - 0.02 15.1 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 Pathogenicity locus HHH PF00633.23 KIK48096.1 - 0.026 14.4 0.0 0.065 13.1 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif NOT2_3_5 PF04153.18 KIK48097.1 - 1.8e-28 99.2 0.1 1.8e-28 99.2 0.1 1.9 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family His_Phos_1 PF00300.22 KIK48099.1 - 2.2e-33 115.6 0.2 3.8e-33 114.8 0.2 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 KIK48099.1 - 0.027 13.8 0.1 0.074 12.4 0.1 1.8 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Ufd2P_core PF10408.9 KIK48100.1 - 7.2e-217 721.9 0.0 8.9e-217 721.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KIK48100.1 - 5.4e-27 93.8 1.5 4.3e-26 90.9 0.8 2.7 2 0 0 2 2 2 1 U-box domain Pex14_N PF04695.13 KIK48100.1 - 1.2 9.8 7.2 2.9 8.5 7.2 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WD40 PF00400.32 KIK48102.1 - 2.8e-35 119.7 16.3 5.7e-07 30.1 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK48102.1 - 3.9e-10 39.9 0.2 0.046 14.0 0.0 5.8 2 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK48102.1 - 6.4e-06 26.0 0.1 0.1 12.6 0.0 3.6 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KIK48102.1 - 8.8e-06 25.7 0.0 0.02 14.8 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A TPR_2 PF07719.17 KIK48102.1 - 0.0038 17.2 0.6 17 5.8 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIK48102.1 - 0.38 11.3 3.3 1 9.9 2.4 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat Cation_efflux PF01545.21 KIK48104.1 - 3e-42 144.6 29.6 3e-42 144.6 29.6 3.0 2 2 1 3 3 3 1 Cation efflux family PDCD2_C PF04194.13 KIK48105.1 - 4.6e-43 147.3 0.1 1.1e-42 146.1 0.1 1.7 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain DUF1771 PF08590.10 KIK48106.1 - 3.4e-15 56.1 6.4 6.3e-15 55.3 6.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf-CCCH PF00642.24 KIK48106.1 - 1.2e-06 28.2 6.9 0.00053 19.8 0.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KIK48106.1 - 3e-06 27.9 2.5 8.6e-05 23.2 0.1 2.6 1 1 1 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 KIK48106.1 - 5.2e-06 26.3 9.0 0.00048 20.1 1.6 2.9 2 1 0 2 2 2 2 Zinc finger domain Smr PF01713.21 KIK48106.1 - 1.3e-05 25.5 0.1 2.9e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 Smr domain zf-C3H1 PF10650.9 KIK48106.1 - 0.00061 19.5 5.4 0.092 12.5 1.3 2.5 2 0 0 2 2 2 2 Putative zinc-finger domain zf-CCCH_2 PF14608.6 KIK48106.1 - 0.00084 19.7 4.4 0.36 11.4 0.6 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KIK48106.1 - 0.0096 16.1 3.5 1.8 8.8 0.2 2.2 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 KIK48106.1 - 0.044 13.6 12.0 1.8 8.5 0.7 3.2 2 1 0 2 2 2 0 CCCH-type zinc finger ATG16 PF08614.11 KIK48107.1 - 5.5e-05 23.5 11.6 5.8e-05 23.4 3.2 2.4 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) HIP1_clath_bdg PF16515.5 KIK48107.1 - 7.8e-05 23.2 9.0 0.033 14.8 0.1 2.3 2 0 0 2 2 2 2 Clathrin-binding domain of Huntingtin-interacting protein 1 Fib_alpha PF08702.10 KIK48107.1 - 0.00013 22.1 3.7 0.056 13.6 1.6 2.3 2 0 0 2 2 2 2 Fibrinogen alpha/beta chain family APG6_N PF17675.1 KIK48107.1 - 0.00014 22.4 6.5 0.016 15.8 1.8 2.2 2 0 0 2 2 2 2 Apg6 coiled-coil region FH2 PF02181.23 KIK48107.1 - 0.0022 17.2 5.4 0.05 12.7 0.5 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain Spc7 PF08317.11 KIK48107.1 - 0.0041 16.0 12.0 0.051 12.5 2.8 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein Atg14 PF10186.9 KIK48107.1 - 0.0052 15.9 1.8 0.016 14.3 0.3 2.0 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 KIK48107.1 - 0.006 17.1 1.6 0.58 10.6 0.3 2.2 2 0 0 2 2 2 1 Fez1 APG17 PF04108.12 KIK48107.1 - 0.0081 15.3 3.8 0.33 10.0 1.0 2.1 2 0 0 2 2 2 1 Autophagy protein Apg17 TPR_MLP1_2 PF07926.12 KIK48107.1 - 0.0081 16.2 8.0 0.45 10.6 1.0 2.2 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein Takusan PF04822.13 KIK48107.1 - 0.014 15.2 1.5 4.3 7.3 0.1 2.8 2 0 0 2 2 2 0 Takusan DUF1664 PF07889.12 KIK48107.1 - 0.019 15.0 5.0 0.17 11.9 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 KIK48107.1 - 0.022 14.9 8.6 0.35 11.1 2.3 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ALIX_LYPXL_bnd PF13949.6 KIK48107.1 - 0.024 13.9 0.5 0.63 9.3 0.0 2.2 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV DUF4618 PF15397.6 KIK48107.1 - 0.028 13.8 3.3 0.07 12.5 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF4201 PF13870.6 KIK48107.1 - 0.058 13.1 10.2 0.067 12.9 3.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) PRKG1_interact PF15898.5 KIK48107.1 - 0.068 14.1 9.9 0.1 13.5 0.5 2.5 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Swi5 PF07061.11 KIK48107.1 - 0.092 12.8 2.9 2.6 8.2 0.2 2.5 2 0 0 2 2 2 0 Swi5 DUF2408 PF10303.9 KIK48107.1 - 0.1 13.1 1.0 6.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) FliJ PF02050.16 KIK48107.1 - 0.11 12.8 4.3 0.16 12.2 0.4 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein YabA PF06156.13 KIK48107.1 - 0.11 13.2 4.9 5.7 7.6 0.1 2.4 2 0 0 2 2 2 0 Initiation control protein YabA CALCOCO1 PF07888.11 KIK48107.1 - 0.15 10.9 9.8 0.075 11.9 2.2 2.1 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like HrpB7 PF09486.10 KIK48107.1 - 0.18 12.1 7.8 2 8.8 2.5 2.4 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Sec5 PF15469.6 KIK48107.1 - 0.19 11.5 3.5 23 4.7 0.0 3.1 2 1 1 3 3 3 0 Exocyst complex component Sec5 DUF2353 PF09789.9 KIK48107.1 - 0.21 10.9 5.6 0.36 10.1 1.6 2.1 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF3818 PF12825.7 KIK48107.1 - 0.21 10.6 0.0 4.9 6.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) DUF5339 PF17274.2 KIK48107.1 - 0.22 12.4 0.8 4.5 8.2 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5339) Laminin_II PF06009.12 KIK48107.1 - 0.27 11.3 5.1 1.2 9.1 1.2 2.4 2 0 0 2 2 2 0 Laminin Domain II DUF5082 PF16888.5 KIK48107.1 - 0.27 11.5 2.8 4.2 7.7 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Phlebovirus_NSM PF07246.11 KIK48107.1 - 0.28 10.5 2.1 1.5 8.1 1.1 2.0 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Golgin_A5 PF09787.9 KIK48107.1 - 0.29 10.5 5.7 4.9 6.5 0.1 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 COG2 PF06148.11 KIK48107.1 - 0.32 11.1 5.0 3.2 7.9 0.5 2.6 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SPATA1_C PF15743.5 KIK48107.1 - 0.34 11.0 5.6 0.88 9.6 0.1 2.7 2 1 0 2 2 2 0 Spermatogenesis-associated C-terminus ZapB PF06005.12 KIK48107.1 - 0.35 11.3 9.0 6.4 7.3 0.3 3.4 2 1 1 3 3 3 0 Cell division protein ZapB HOOK PF05622.12 KIK48107.1 - 0.38 8.8 6.6 0.16 10.1 1.3 2.0 2 0 0 2 2 2 0 HOOK protein CC2-LZ PF16516.5 KIK48107.1 - 0.4 11.1 4.5 10 6.5 0.3 2.3 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF2203 PF09969.9 KIK48107.1 - 0.5 11.1 4.7 11 6.8 0.9 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Snapin_Pallidin PF14712.6 KIK48107.1 - 0.59 10.6 5.2 3.5 8.1 1.6 2.5 2 0 0 2 2 2 0 Snapin/Pallidin YscO-like PF16789.5 KIK48107.1 - 0.8 9.7 8.4 0.5 10.4 1.3 2.1 2 0 0 2 2 2 0 YscO-like protein DUF3584 PF12128.8 KIK48107.1 - 0.83 7.1 6.2 0.11 10.0 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) SOGA PF11365.8 KIK48107.1 - 1.2 10.3 9.9 18 6.5 0.4 3.1 2 1 1 3 3 3 0 Protein SOGA ERM PF00769.19 KIK48107.1 - 1.3 8.8 8.9 0.57 10.0 1.9 2.3 2 1 0 2 2 2 0 Ezrin/radixin/moesin family HalX PF08663.10 KIK48107.1 - 1.5 9.2 8.8 0.1 12.9 0.6 2.8 2 1 0 2 2 2 0 HalX domain CENP-H PF05837.12 KIK48107.1 - 1.5 9.2 7.7 1.4 9.4 2.1 2.5 2 1 0 2 2 2 0 Centromere protein H (CENP-H) DUF4140 PF13600.6 KIK48107.1 - 1.7 9.1 5.6 7.8 7.0 0.0 3.0 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Myosin_tail_1 PF01576.19 KIK48107.1 - 2 6.1 12.4 0.16 9.7 2.3 2.0 2 0 0 2 2 2 0 Myosin tail Seryl_tRNA_N PF02403.22 KIK48107.1 - 2.3 8.5 7.3 8.9 6.6 1.3 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Prefoldin_2 PF01920.20 KIK48107.1 - 2.9 7.9 5.8 21 5.1 0.4 2.7 2 1 1 3 3 3 0 Prefoldin subunit Tropomyosin_1 PF12718.7 KIK48107.1 - 3.1 7.9 12.6 1.7 8.8 3.1 2.2 2 0 0 2 2 2 0 Tropomyosin like FlaC_arch PF05377.11 KIK48107.1 - 4 7.9 7.8 12 6.4 0.5 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 KIK48107.1 - 4.1 7.5 10.1 0.88 9.6 0.5 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 KIK48107.1 - 4.3 7.4 5.0 3.7 7.6 0.7 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Lebercilin PF15619.6 KIK48107.1 - 4.8 6.8 10.2 10 5.7 4.2 2.5 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 KIK48107.1 - 5.9 6.2 9.2 12 5.1 2.2 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding SlyX PF04102.12 KIK48107.1 - 6.9 7.4 8.2 6.5 7.5 1.0 3.3 2 1 1 3 3 3 0 SlyX Cluap1 PF10234.9 KIK48107.1 - 8.5 5.7 7.5 3.1 7.1 3.0 2.0 2 0 0 2 2 2 0 Clusterin-associated protein-1 DHR10 PF18595.1 KIK48107.1 - 9.7 6.3 13.4 7.4 6.7 1.6 2.7 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Fungal_trans PF04082.18 KIK48110.1 - 1.2e-23 83.5 0.4 2.2e-23 82.6 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK48110.1 - 2.2e-05 24.5 9.3 4.4e-05 23.5 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ras PF00071.22 KIK48111.1 - 1.1e-52 177.9 0.0 1.4e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK48111.1 - 7.4e-22 77.8 0.0 1e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK48111.1 - 5.7e-07 29.2 0.0 7.3e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KIK48111.1 - 0.00043 19.8 0.0 0.00068 19.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KIK48111.1 - 0.0067 16.5 0.0 0.0097 16.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KIK48111.1 - 0.0092 15.4 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KIK48111.1 - 0.034 13.0 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) RsgA_GTPase PF03193.16 KIK48111.1 - 0.046 13.6 0.0 9.1 6.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KIK48111.1 - 0.087 13.2 0.0 0.18 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AC_N PF16214.5 KIK48112.1 - 6.4 5.8 7.1 13 4.7 7.1 1.6 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region TRAUB PF08164.12 KIK48113.1 - 9e-30 103.0 0.1 9e-30 103.0 0.1 2.1 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KIK48113.1 - 4.2e-23 82.6 0.1 4.2e-23 82.6 0.1 3.1 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor Sporozoite_P67 PF05642.11 KIK48113.1 - 1.7 6.6 7.9 3.2 5.7 7.9 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PX PF00787.24 KIK48114.1 - 4.7e-24 84.6 1.1 7.7e-23 80.6 0.0 2.6 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 KIK48114.1 - 7.1e-05 22.5 10.3 0.033 13.7 0.9 2.2 2 0 0 2 2 2 2 Vps5 C terminal like FAM92 PF06730.11 KIK48114.1 - 0.021 14.3 0.3 0.021 14.3 0.3 1.8 2 0 0 2 2 2 0 FAM92 protein Peptidase_C10 PF01640.17 KIK48114.1 - 0.1 12.9 0.9 0.21 11.9 0.9 1.4 1 0 0 1 1 1 0 Peptidase C10 family AAA_assoc_C PF09821.9 KIK48114.1 - 0.11 13.1 1.3 0.62 10.6 0.7 2.5 2 0 0 2 2 2 0 C-terminal AAA-associated domain BAR PF03114.18 KIK48114.1 - 0.15 11.7 8.7 0.016 14.9 2.3 2.0 2 0 0 2 2 2 0 BAR domain FapA PF03961.13 KIK48114.1 - 6.9 5.2 6.2 0.61 8.6 0.9 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A Zn_clus PF00172.18 KIK48115.1 - 7.8e-05 22.7 8.5 0.00014 21.9 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PQ-loop PF04193.14 KIK48117.1 - 7.9e-18 64.0 8.2 2e-13 49.9 1.3 2.7 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 KIK48117.1 - 0.0045 17.8 4.5 0.0072 17.2 4.5 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor Ferlin_C PF16165.5 KIK48117.1 - 0.099 12.6 0.0 0.099 12.6 0.0 2.1 1 1 1 2 2 2 0 Ferlin C-terminus Clathrin PF00637.20 KIK48118.1 - 2e-202 663.2 24.0 1.2e-32 112.8 0.1 7.7 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KIK48118.1 - 5.4e-37 124.3 0.3 4e-07 30.0 0.1 6.8 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KIK48118.1 - 3.6e-32 110.1 0.1 1.9e-31 107.8 0.1 2.4 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.10 KIK48118.1 - 3.8e-12 45.3 2.2 1.2e-11 43.7 0.1 2.8 3 0 0 3 3 3 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 KIK48118.1 - 1.8e-05 24.0 7.9 0.066 12.3 0.2 4.7 4 0 0 4 4 4 2 Coatomer WD associated region Vps39_1 PF10366.9 KIK48118.1 - 0.0012 19.1 3.7 5.2 7.4 0.1 5.6 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 TPR_1 PF00515.28 KIK48118.1 - 0.022 14.6 6.0 15 5.6 0.2 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 KIK48118.1 - 0.097 13.0 0.1 45 4.6 0.0 4.9 6 0 0 6 6 5 0 PPR repeat TPR_8 PF13181.6 KIK48118.1 - 1 9.8 9.3 7.8 7.0 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK48118.1 - 1.9 8.8 11.5 42 4.6 0.4 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK48118.1 - 2.7 8.2 9.7 39 4.6 0.2 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat F-box PF00646.33 KIK48119.1 - 3.9e-06 26.6 0.5 1.5e-05 24.7 0.5 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK48119.1 - 0.00015 21.5 0.3 0.00049 19.9 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KIK48119.1 - 0.15 11.9 1.6 0.55 10.1 0.4 2.4 2 0 0 2 2 2 0 F-box Endonuclease_7 PF02945.15 KIK48119.1 - 0.32 10.9 2.3 1.4 8.9 0.3 2.6 2 0 0 2 2 2 0 Recombination endonuclease VII Cation_efflux PF01545.21 KIK48120.1 - 7.6e-12 45.4 12.7 2e-11 44.0 5.1 2.0 2 0 0 2 2 2 2 Cation efflux family SepZ PF06066.11 KIK48120.1 - 0.04 14.1 1.8 0.086 13.1 0.4 2.0 1 1 1 2 2 2 0 SepZ SAM_PNT PF02198.16 KIK48120.1 - 0.063 13.3 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF2644 PF10841.8 KIK48120.1 - 0.064 13.5 0.2 0.17 12.1 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2644) DUF2678 PF10856.8 KIK48120.1 - 0.22 11.5 5.1 0.36 10.8 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2678) EamA PF00892.20 KIK48121.1 - 1.4e-05 25.3 32.6 3.5e-05 24.0 9.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family CPSase_L_D2 PF02786.17 KIK48122.1 - 8e-80 267.3 0.0 1.5e-79 266.4 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KIK48122.1 - 2.8e-67 226.3 0.0 4.6e-67 225.6 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KIK48122.1 - 9.2e-40 135.6 0.1 1.9e-39 134.6 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KIK48122.1 - 1.6e-29 102.1 0.0 5.8e-29 100.4 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KIK48122.1 - 3.4e-28 99.0 0.0 7.1e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KIK48122.1 - 8.2e-18 64.0 3.4 8.2e-18 64.0 3.4 2.1 2 0 0 2 2 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KIK48122.1 - 5.6e-12 45.3 3.6 1.1e-06 28.3 0.1 2.8 2 1 1 3 3 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KIK48122.1 - 2.5e-10 40.2 0.0 5.3e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KIK48122.1 - 1.3e-07 31.4 0.0 2.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 KIK48122.1 - 7.7e-06 25.3 0.7 0.002 17.4 0.1 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 KIK48122.1 - 1.4e-05 25.2 0.0 3.8e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KIK48122.1 - 1.7e-05 25.4 0.8 0.32 11.7 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_4 PF13535.6 KIK48122.1 - 0.00067 19.3 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GCV_H PF01597.19 KIK48122.1 - 0.0009 19.1 2.8 0.0033 17.3 0.5 2.9 3 1 1 4 4 4 1 Glycine cleavage H-protein RimK PF08443.11 KIK48122.1 - 0.002 17.7 0.0 0.0047 16.5 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain NQRA PF05896.11 KIK48122.1 - 0.0047 16.4 0.4 0.0094 15.4 0.4 1.4 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RnfC_N PF13375.6 KIK48122.1 - 0.011 15.7 0.7 0.056 13.4 0.7 2.2 2 1 0 2 2 2 0 RnfC Barrel sandwich hybrid domain GARS_A PF01071.19 KIK48122.1 - 0.02 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 KIK48122.1 - 0.023 13.9 0.0 0.05 12.8 0.0 1.5 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp DUF2118 PF09891.9 KIK48122.1 - 0.025 14.5 0.2 0.35 10.8 0.3 2.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2118) PTS_EIIA_1 PF00358.20 KIK48122.1 - 0.032 14.0 0.4 0.32 10.8 0.2 2.7 2 1 1 3 3 3 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PNPase PF03726.14 KIK48122.1 - 0.06 13.8 0.3 0.22 12.0 0.1 2.1 2 0 0 2 2 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain NMO PF03060.15 KIK48123.1 - 8.3e-39 133.9 3.1 2.5e-32 112.6 0.4 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 KIK48123.1 - 0.00019 20.6 0.0 0.00029 19.9 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KIK48123.1 - 0.013 14.6 0.1 0.019 14.0 0.1 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase LSM PF01423.22 KIK48124.1 - 4.5e-16 58.3 0.0 6.3e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 LSM domain INSIG PF07281.12 KIK48128.1 - 0.051 13.2 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) DUF2205 PF10224.9 KIK48131.1 - 3.1e-12 46.3 0.3 3.4e-12 46.2 0.3 1.1 1 0 0 1 1 1 1 Short coiled-coil protein YabA PF06156.13 KIK48131.1 - 0.0058 17.2 0.5 0.0066 17.1 0.5 1.1 1 0 0 1 1 1 1 Initiation control protein YabA KASH_CCD PF14662.6 KIK48131.1 - 0.02 14.7 0.4 0.021 14.6 0.4 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH WASH_WAHD PF11945.8 KIK48131.1 - 0.022 14.3 0.2 0.025 14.1 0.2 1.0 1 0 0 1 1 1 0 WAHD domain of WASH complex DivIC PF04977.15 KIK48131.1 - 0.027 14.2 0.4 0.035 13.9 0.4 1.3 1 0 0 1 1 1 0 Septum formation initiator TLE_N PF03920.15 KIK48131.1 - 0.047 13.8 0.0 0.05 13.7 0.0 1.2 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain bZIP_2 PF07716.15 KIK48131.1 - 0.085 13.0 0.1 0.16 12.1 0.1 1.6 1 1 0 1 1 1 0 Basic region leucine zipper HALZ PF02183.18 KIK48131.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper SHR3_chaperone PF08229.11 KIK48132.1 - 7.3e-49 165.3 0.2 8e-49 165.2 0.2 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 GFO_IDH_MocA PF01408.22 KIK48135.1 - 5e-20 72.5 0.0 7.1e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA PF01408.22 KIK48136.1 - 9e-20 71.7 0.1 1.3e-19 71.2 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold OHCU_decarbox PF09349.10 KIK48137.1 - 1.2e-32 113.5 0.0 1.5e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase DnaJ PF00226.31 KIK48138.1 - 1.9e-19 69.5 0.4 6.5e-19 67.8 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain TPH PF13868.6 KIK48138.1 - 0.00046 18.8 16.5 0.00064 18.3 16.5 1.2 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain CDT1_C PF16679.5 KIK48138.1 - 0.087 13.3 5.0 16 6.0 5.0 2.2 1 1 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain Abhydrolase_1 PF00561.20 KIK48139.1 - 6.2e-27 94.9 0.1 7.3e-27 94.6 0.1 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIK48139.1 - 9.6e-14 52.5 0.1 1.2e-13 52.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK48139.1 - 1.4e-10 40.9 0.0 2.9e-10 39.8 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KIK48139.1 - 0.00016 21.9 0.0 0.00039 20.6 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain Peptidase_S15 PF02129.18 KIK48139.1 - 0.0049 16.5 0.0 0.0075 15.9 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Lysine_decarbox PF03641.14 KIK48139.1 - 0.064 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Possible lysine decarboxylase Abhydrolase_5 PF12695.7 KIK48139.1 - 0.19 11.5 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Imm52 PF15579.6 KIK48140.1 - 0.0041 16.9 0.1 0.5 10.3 0.0 2.1 1 1 1 2 2 2 2 Immunity protein 52 Abhydrolase_1 PF00561.20 KIK48142.1 - 2.7e-12 46.9 0.0 3.8e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK48142.1 - 7.1e-06 25.5 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 NADH-u_ox-rdase PF10785.9 KIK48143.1 - 1.6e-32 112.0 0.7 2.3e-32 111.5 0.7 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KIK48143.1 - 1.8e-11 43.9 0.0 2.7e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Acyl_transf_3 PF01757.22 KIK48143.1 - 0.033 13.2 1.1 0.044 12.8 1.1 1.1 1 0 0 1 1 1 0 Acyltransferase family zf-RanBP PF00641.18 KIK48144.1 - 2.3e-10 39.6 22.4 0.0001 21.6 2.0 3.5 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others C1_2 PF03107.16 KIK48144.1 - 0.019 15.2 7.6 5 7.5 0.1 3.5 3 0 0 3 3 3 0 C1 domain Vps36-NZF-N PF16988.5 KIK48144.1 - 0.033 13.6 15.3 0.92 8.9 0.3 4.0 3 1 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 KIK48144.1 - 0.56 10.3 5.7 21 5.3 0.0 3.9 3 1 0 3 3 3 0 Sec23/Sec24 zinc finger PHD_2 PF13831.6 KIK48144.1 - 0.96 9.1 4.2 30 4.3 0.1 3.5 3 0 0 3 3 3 0 PHD-finger DZR PF12773.7 KIK48144.1 - 7.1 6.7 11.6 1.5 8.9 3.4 2.5 1 1 1 2 2 2 0 Double zinc ribbon Pkinase PF00069.25 KIK48145.1 - 1.5e-71 240.8 0.0 1.8e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK48145.1 - 4.8e-32 111.3 0.0 6.6e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK48145.1 - 0.008 15.2 0.0 0.16 10.9 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIK48145.1 - 0.014 15.3 0.9 0.035 14.0 0.2 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK48145.1 - 0.024 14.0 0.1 0.13 11.6 0.0 2.0 1 1 1 2 2 2 0 Kinase-like NUDIX PF00293.28 KIK48146.1 - 2.6e-11 43.7 0.0 3.6e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain ActA PF05058.12 KIK48146.1 - 0.29 9.5 0.0 0.4 9.0 0.0 1.1 1 0 0 1 1 1 0 ActA Protein p450 PF00067.22 KIK48147.1 - 1.2e-64 218.8 0.0 1.3e-64 218.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ANAPC4_WD40 PF12894.7 KIK48148.1 - 2.6e-06 27.6 0.9 0.055 13.8 0.0 4.3 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK48148.1 - 5e-06 27.1 9.1 0.12 13.3 1.5 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KIK48148.1 - 0.064 12.3 0.0 3.1 6.7 0.0 2.5 2 1 1 3 3 3 0 Coatomer WD associated region Peptidase_C23 PF05379.11 KIK48148.1 - 0.11 12.6 0.0 0.71 10.0 0.0 2.2 2 0 0 2 2 2 0 Carlavirus endopeptidase zf-C2H2_4 PF13894.6 KIK48150.1 - 0.0012 19.5 5.9 0.0012 19.5 5.9 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIK48150.1 - 0.0018 18.6 14.6 0.0026 18.1 6.5 3.0 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK48150.1 - 0.0082 16.5 0.1 0.0082 16.5 0.1 3.0 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KIK48150.1 - 0.012 15.6 5.6 0.012 15.6 5.6 2.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 KIK48150.1 - 0.086 13.2 6.7 0.27 11.6 6.7 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KIK48150.1 - 0.087 13.3 2.5 0.087 13.3 2.5 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Actin_micro PF17003.5 KIK48150.1 - 4.4 6.4 8.7 1.1 8.4 0.3 2.0 1 1 1 2 2 2 0 Putative actin-like family DUF2805 PF10985.8 KIK48151.1 - 0.022 15.1 2.2 0.028 14.8 2.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2805) DUF4490 PF14892.6 KIK48151.1 - 0.06 13.4 0.4 0.066 13.3 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4490) WD40 PF00400.32 KIK48152.1 - 6.4e-42 140.7 29.3 1.1e-05 26.0 0.5 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK48152.1 - 6.5e-23 80.9 4.4 4e-05 23.8 0.2 6.0 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK48152.1 - 1.2e-06 27.7 0.2 0.13 11.2 0.0 4.4 3 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK48152.1 - 4.3e-06 25.7 3.0 0.24 10.0 0.3 4.0 2 2 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 KIK48152.1 - 2e-05 24.5 0.5 0.00099 19.0 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KIK48152.1 - 0.00029 20.3 0.9 0.017 14.5 0.0 3.5 1 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIK48152.1 - 0.0019 17.6 0.0 0.51 9.6 0.0 2.8 3 1 0 3 3 3 1 WD40-like domain PQQ_3 PF13570.6 KIK48152.1 - 0.0019 18.6 0.1 3.4 8.3 0.0 4.1 4 0 0 4 4 4 1 PQQ-like domain PQQ_2 PF13360.6 KIK48152.1 - 0.005 16.4 1.1 0.053 13.1 0.4 2.3 2 1 0 2 2 2 1 PQQ-like domain PALB2_WD40 PF16756.5 KIK48152.1 - 0.037 13.0 3.7 4.1 6.2 0.4 3.0 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 KIK48152.1 - 0.075 11.3 0.0 17 3.6 0.0 2.9 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF4527 PF15030.6 KIK48152.1 - 0.25 10.7 0.0 0.36 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) Hira PF07569.11 KIK48152.1 - 0.26 11.0 1.5 14 5.3 0.2 3.8 3 1 1 4 4 4 0 TUP1-like enhancer of split DnaJ PF00226.31 KIK48153.1 - 7.5e-22 77.2 1.0 1.3e-21 76.5 0.3 1.7 2 0 0 2 2 2 1 DnaJ domain SH3_1 PF00018.28 KIK48155.1 - 1.6e-18 66.0 2.6 2.1e-08 33.7 0.3 3.3 2 1 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KIK48155.1 - 1.2e-12 47.5 2.1 2.6e-05 24.0 0.1 2.7 2 1 0 2 2 2 2 Variant SH3 domain SAM_2 PF07647.17 KIK48155.1 - 1.8e-12 47.2 0.0 3.6e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KIK48155.1 - 2.6e-12 47.0 0.0 4.5e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 KIK48155.1 - 4.4e-07 29.5 0.3 0.0013 18.4 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain RA PF00788.23 KIK48155.1 - 2.8e-06 27.9 0.0 7.7e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_3 PF08239.11 KIK48155.1 - 0.0042 17.3 5.2 0.2 12.0 0.5 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain SAM_PNT PF02198.16 KIK48155.1 - 0.03 14.3 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain SlyX PF04102.12 KIK48155.1 - 0.05 14.2 1.2 0.05 14.2 1.2 2.3 3 0 0 3 3 3 0 SlyX FokI_N PF02981.15 KIK48155.1 - 0.18 11.9 0.2 0.61 10.3 0.0 1.9 2 0 0 2 2 2 0 Restriction endonuclease FokI, recognition domain KLRAQ PF10205.9 KIK48155.1 - 0.22 11.8 1.5 0.25 11.6 0.2 1.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein CENP-H PF05837.12 KIK48155.1 - 0.94 9.9 3.2 0.45 11.0 0.4 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Aldo_ket_red PF00248.21 KIK48156.1 - 1.7e-40 139.0 0.0 2.1e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Epimerase PF01370.21 KIK48161.1 - 0.1 12.1 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Plavaka PF18759.1 KIK48162.1 - 5.5e-32 111.3 0.0 1e-31 110.4 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase XPB_DRD PF18458.1 KIK48162.1 - 0.055 13.4 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Xeroderma pigmentosum group B helicase damage recognition domain DUF4820 PF16091.5 KIK48162.1 - 5.2 6.4 7.7 8.8 5.6 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) LRR_4 PF12799.7 KIK48163.1 - 0.021 15.2 7.2 7 7.2 0.5 6.2 6 1 2 8 8 8 0 Leucine Rich repeats (2 copies) Vma12 PF11712.8 KIK48164.1 - 2.3e-12 47.1 0.0 3.4e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3619 PF12279.8 KIK48164.1 - 0.003 17.9 0.0 0.0053 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3619) BRAP2 PF07576.12 KIK48165.1 - 5.4e-28 97.1 0.0 9.4e-28 96.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KIK48165.1 - 7.3e-20 71.1 3.2 1.6e-19 70.0 3.2 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KIK48165.1 - 2.4e-08 34.2 9.5 2.4e-08 34.2 9.5 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK48165.1 - 6.1e-06 26.0 9.4 6.1e-06 26.0 9.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIK48165.1 - 1.4e-05 24.8 7.7 3.4e-05 23.6 7.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIK48165.1 - 1.9e-05 24.3 4.9 5e-05 22.9 4.9 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KIK48165.1 - 1.9e-05 24.8 5.8 5.8e-05 23.3 5.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KIK48165.1 - 5.5e-05 23.1 5.5 0.00018 21.4 5.5 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIK48165.1 - 0.00079 19.2 6.6 0.00079 19.2 6.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK48165.1 - 0.0038 17.2 6.7 0.0038 17.2 6.7 2.0 2 0 0 2 2 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KIK48165.1 - 0.0047 17.0 3.3 0.011 15.8 3.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KIK48165.1 - 0.048 13.5 6.2 0.12 12.2 6.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UBP_var PF17807.1 KIK48165.1 - 0.11 12.3 0.4 0.25 11.1 0.4 1.5 1 0 0 1 1 1 0 Variant UBP zinc finger Rab5-bind PF09311.11 KIK48165.1 - 0.45 9.9 21.4 0.3 10.4 12.3 2.1 1 1 1 2 2 2 0 Rabaptin-like protein DUF4407 PF14362.6 KIK48165.1 - 4.9 6.4 13.2 8.9 5.6 13.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.6 KIK48165.1 - 5.8 5.4 15.6 8.1 4.9 15.6 1.1 1 0 0 1 1 1 0 AAA domain Atx10homo_assoc PF09759.9 KIK48166.1 - 3e-26 91.3 0.0 8.7e-26 89.8 0.0 1.8 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 KIK48166.1 - 0.0019 18.1 0.0 0.19 11.8 0.0 3.6 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 KIK48166.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Armadillo-like Leo1 PF04004.13 KIK48167.1 - 3.1e-51 173.5 0.4 3.1e-51 173.5 0.4 2.2 2 0 0 2 2 2 1 Leo1-like protein NifT PF06988.11 KIK48168.1 - 0.033 13.9 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 NifT/FixU protein NifT PF06988.11 KIK48171.1 - 0.023 14.5 0.0 0.062 13.1 0.0 1.7 1 0 0 1 1 1 0 NifT/FixU protein DUF3782 PF12644.7 KIK48171.1 - 0.059 13.5 0.1 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) YqaJ PF09588.10 KIK48171.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain DUF3399 PF11879.8 KIK48173.1 - 0.013 15.8 0.2 0.023 15.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) Cnd2 PF05786.14 KIK48175.1 - 1.2e-179 599.6 18.1 2.8e-179 598.4 18.1 1.4 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KIK48175.1 - 0.22 11.7 1.9 0.46 10.7 0.0 2.5 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DUF1192 PF06698.11 KIK48176.1 - 0.04 14.0 0.1 0.11 12.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DNA_pol_B PF00136.21 KIK48178.1 - 1.2e-146 489.1 0.2 1.6e-146 488.7 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KIK48178.1 - 2.4e-87 293.2 0.0 4e-87 292.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KIK48178.1 - 9.2e-18 64.5 8.0 2e-17 63.4 8.0 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KIK48178.1 - 0.0001 21.4 0.1 0.00019 20.4 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 KIK48178.1 - 0.0066 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KIK48178.1 - 0.0089 16.0 0.3 0.033 14.2 0.3 2.0 1 1 0 1 1 1 1 RNase_H superfamily C1_1 PF00130.22 KIK48178.1 - 3.2 7.7 6.5 1.4 8.8 2.9 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PMM PF03332.13 KIK48179.1 - 1.1e-105 352.2 2.2 1.3e-105 352.0 2.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KIK48179.1 - 0.00024 20.9 0.0 0.0023 17.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KIK48179.1 - 0.0096 15.5 0.0 2.8 7.4 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase DUF334 PF03904.13 KIK48179.1 - 0.057 13.0 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) CTV_P13 PF06922.11 KIK48179.1 - 0.071 13.2 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 Citrus tristeza virus P13 protein bVLRF1 PF18826.1 KIK48180.1 - 1.1e-65 220.1 0.0 1.8e-65 219.4 0.0 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor DUF5399 PF17377.2 KIK48180.1 - 0.43 10.4 3.4 10 6.0 0.6 3.1 4 0 0 4 4 4 0 Family of unknown function (DUF5399) zf-C2H2 PF00096.26 KIK48181.1 - 0.00023 21.5 2.9 0.0013 19.1 0.1 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK48181.1 - 0.00095 19.8 3.2 0.67 10.9 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KIK48181.1 - 0.0034 17.6 0.4 0.0046 17.1 0.4 1.1 1 0 0 1 1 1 1 Aberrant zinc-finger DUF4729 PF15866.5 KIK48181.1 - 0.066 12.5 0.7 0.092 12.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4729) Ribosomal_L7Ae PF01248.26 KIK48182.1 - 7.4e-23 80.1 0.0 8.6e-23 79.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Actin PF00022.19 KIK48183.1 - 9.9e-41 139.7 0.0 1.6e-39 135.7 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KIK48183.1 - 0.055 12.3 0.0 0.14 10.9 0.0 1.7 1 1 0 1 1 1 0 MreB/Mbl protein SQHop_cyclase_N PF13249.6 KIK48184.1 - 3.7e-53 180.5 1.8 1.7e-44 152.0 0.1 3.3 2 1 1 3 3 3 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KIK48184.1 - 1.1e-48 166.0 2.5 8.7e-45 153.2 0.4 2.9 2 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 KIK48184.1 - 1.8e-32 110.8 7.5 4.2e-09 36.0 0.0 6.1 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 KIK48184.1 - 0.0016 17.9 0.2 6.7 5.9 0.0 4.2 2 2 1 4 4 4 2 Pectic acid lyase NIR_SIR PF01077.22 KIK48185.1 - 5.3e-53 178.8 0.0 3.1e-48 163.3 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KIK48185.1 - 5.2e-33 112.7 0.1 1.6e-16 59.9 0.0 2.4 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KIK48185.1 - 2.9e-27 95.6 0.0 5.2e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Collagen PF01391.18 KIK48185.1 - 1.9e-11 43.5 55.4 4.9e-08 32.6 24.9 2.4 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Aminotran_5 PF00266.19 KIK48186.1 - 6.3e-31 107.7 0.0 8.2e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 KIK48186.1 - 0.0018 18.3 0.6 0.029 14.4 0.3 2.4 2 0 0 2 2 2 1 B12 binding domain WD40 PF00400.32 KIK48187.1 - 2.1e-09 37.9 12.4 0.25 12.3 0.1 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat HAND PF09110.11 KIK48187.1 - 0.09 13.5 11.5 0.25 12.1 11.5 1.7 1 0 0 1 1 1 0 HAND Tli4_N PF18443.1 KIK48187.1 - 2.4 8.5 5.3 12 6.2 5.3 2.1 1 1 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain SAC3_GANP PF03399.16 KIK48190.1 - 4.6e-26 91.9 2.9 1.7e-24 86.7 2.9 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KIK48190.1 - 1.1e-07 31.9 0.4 2.9e-07 30.6 0.1 1.8 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family EF-hand_2 PF09068.11 KIK48190.1 - 0.063 13.4 0.4 7.3 6.8 0.1 2.4 2 0 0 2 2 2 0 EF hand Cytochrom_C1 PF02167.15 KIK48191.1 - 6.3e-95 317.0 0.0 7.6e-95 316.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KIK48191.1 - 0.0073 16.6 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KIK48191.1 - 0.076 14.2 0.1 0.18 13.0 0.1 1.9 1 1 0 1 1 1 0 Cytochrome c DUF2076 PF09849.9 KIK48192.1 - 6.5 6.7 17.6 8.1 6.4 17.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Velvet PF11754.8 KIK48193.1 - 9.1e-34 117.5 7.5 1.8e-21 77.2 0.0 3.0 2 1 1 3 3 3 2 Velvet factor Tim17 PF02466.19 KIK48194.1 - 1.5e-25 89.7 6.5 2.1e-25 89.2 6.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TPR_11 PF13414.6 KIK48195.1 - 2.3e-14 52.8 9.8 2e-06 27.3 0.7 4.4 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.28 KIK48195.1 - 2.8e-14 52.2 4.5 4.5e-06 26.3 0.0 4.9 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIK48195.1 - 3.8e-14 51.6 6.2 1.2e-05 25.0 0.0 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIK48195.1 - 1.5e-11 44.8 5.8 0.00012 22.6 2.0 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIK48195.1 - 3.5e-10 39.5 1.2 0.019 15.3 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIK48195.1 - 1.8e-09 37.8 3.8 0.011 16.0 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK48195.1 - 4.9e-09 36.6 4.2 0.00015 22.2 0.9 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK48195.1 - 1.5e-08 34.7 6.5 0.013 16.2 0.1 4.5 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIK48195.1 - 7.6e-08 32.0 5.3 0.02 15.1 0.0 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 KIK48195.1 - 2.8e-05 23.5 1.5 4e-05 23.0 1.5 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIK48195.1 - 8.6e-05 22.9 2.7 0.96 10.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIK48195.1 - 0.00014 21.6 6.6 0.13 12.2 0.0 3.7 3 1 1 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK48195.1 - 0.00033 20.8 0.7 0.21 11.8 0.1 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 KIK48195.1 - 0.0029 17.6 3.5 1.5 9.0 0.0 3.0 2 1 1 3 3 3 2 MIT (microtubule interacting and transport) domain ANAPC5 PF12862.7 KIK48195.1 - 0.0059 16.7 0.1 0.016 15.3 0.1 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 DUF3856 PF12968.7 KIK48195.1 - 0.0086 16.1 0.4 0.93 9.6 0.0 2.5 2 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_7 PF13176.6 KIK48195.1 - 0.0098 15.9 7.1 1.1 9.5 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 KIK48195.1 - 0.014 15.7 4.4 0.061 13.7 0.2 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KIK48195.1 - 0.027 14.9 2.2 0.18 12.3 2.2 2.3 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 KIK48195.1 - 0.03 14.5 0.8 4.1 7.6 0.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 KIK48195.1 - 0.037 14.1 1.9 9.1 6.4 0.2 2.8 3 0 0 3 3 3 0 Exonuclease VII small subunit E3_UbLigase_R4 PF13764.6 KIK48195.1 - 0.07 11.3 0.1 1.1 7.3 0.0 2.0 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase UBR4 AAA_33 PF13671.6 KIK48196.1 - 3.9e-11 43.3 0.1 5e-06 26.7 0.0 2.2 1 1 1 2 2 2 2 AAA domain KTI12 PF08433.10 KIK48196.1 - 0.0065 16.0 0.0 0.23 10.9 0.0 2.0 1 1 1 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KIK48196.1 - 0.0065 17.0 0.0 0.071 13.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.11 KIK48196.1 - 0.013 15.6 0.0 0.017 15.2 0.0 1.4 1 1 0 1 1 1 0 tRNA ligase kinase domain dNK PF01712.19 KIK48196.1 - 0.038 13.8 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase 6PF2K PF01591.18 KIK48196.1 - 0.059 12.7 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase APS_kinase PF01583.20 KIK48196.1 - 0.087 12.7 0.0 0.25 11.2 0.0 1.7 1 1 1 2 2 2 0 Adenylylsulphate kinase AAA_22 PF13401.6 KIK48196.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KIK48196.1 - 0.17 11.6 0.0 0.42 10.4 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Cyclin_N PF00134.23 KIK48197.1 - 1.4e-10 41.0 0.1 8.2e-10 38.5 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain SDH_alpha PF03313.15 KIK48198.1 - 2.8e-100 335.3 2.1 3.6e-100 334.9 2.1 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 KIK48198.1 - 8.7e-56 188.6 0.0 1.6e-55 187.7 0.0 1.4 1 0 0 1 1 1 1 Serine dehydratase beta chain RhoGAP PF00620.27 KIK48200.1 - 2e-41 141.4 0.0 3.7e-41 140.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KIK48200.1 - 3e-15 56.6 0.0 7.8e-15 55.3 0.0 1.8 1 0 0 1 1 1 1 PH domain PX PF00787.24 KIK48200.1 - 9.4e-08 32.0 0.0 2.1e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 PX domain PH_11 PF15413.6 KIK48200.1 - 1.8e-05 25.1 0.0 5.7e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KIK48200.1 - 0.009 16.3 0.1 0.037 14.3 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain NYD-SP28_assoc PF14775.6 KIK48200.1 - 0.17 12.0 0.8 0.34 11.0 0.8 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain Cep57_CLD_2 PF14197.6 KIK48200.1 - 0.4 10.8 5.0 1 9.5 5.0 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DNA_ligase_A_M PF01068.21 KIK48201.1 - 9e-24 84.3 0.0 1.6e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KIK48201.1 - 2.7e-13 50.6 0.0 2.3e-12 47.6 0.0 2.1 2 0 0 2 2 2 1 DNA ligase N terminus RNA_ligase PF09414.10 KIK48201.1 - 0.01 16.2 0.0 0.023 15.0 0.0 1.7 1 1 0 1 1 1 0 RNA ligase DHR10 PF18595.1 KIK48201.1 - 0.33 11.0 3.9 0.92 9.6 3.9 1.7 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain AAA PF00004.29 KIK48202.1 - 0.00065 20.1 0.0 0.0012 19.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KIK48202.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 KIK48202.1 - 0.023 14.4 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 KIK48202.1 - 0.047 13.7 0.0 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KIK48202.1 - 0.089 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CPT PF07931.12 KIK48202.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.6 KIK48202.1 - 0.14 12.3 0.0 0.42 10.7 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain zf-C2H2 PF00096.26 KIK48203.1 - 1.9e-20 72.1 26.0 0.0014 18.9 0.2 7.7 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK48203.1 - 2.2e-17 62.6 26.9 2e-06 28.0 0.3 5.6 5 0 0 5 5 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIK48203.1 - 3.4e-13 49.2 33.9 0.00066 20.3 1.9 8.2 8 0 0 8 8 6 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KIK48203.1 - 1.8e-06 28.2 20.8 0.015 15.6 4.5 4.2 3 1 1 4 4 4 3 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KIK48203.1 - 6.3e-06 26.3 12.0 0.0054 17.0 0.5 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KIK48203.1 - 9.1e-05 22.4 18.8 0.96 9.5 0.0 6.0 6 0 0 6 6 6 3 C2H2-type zinc finger zf_Hakai PF18408.1 KIK48203.1 - 0.0013 18.4 2.9 0.59 9.9 0.0 4.0 4 0 0 4 4 4 2 C2H2 Hakai zinc finger domain zf-BED PF02892.15 KIK48203.1 - 0.0039 17.2 6.9 0.57 10.3 0.0 3.8 3 0 0 3 3 3 1 BED zinc finger FOXP-CC PF16159.5 KIK48203.1 - 0.012 16.2 31.9 0.043 14.4 0.2 6.3 4 1 2 7 7 6 0 FOXP coiled-coil domain PyrI_C PF02748.15 KIK48203.1 - 0.03 14.2 2.1 0.27 11.2 0.2 2.8 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf_ZIC PF18366.1 KIK48203.1 - 0.14 12.3 16.3 0.59 10.3 0.1 5.2 5 1 0 5 5 5 0 Zic proteins zinc finger domain zf-C2H2_2 PF12756.7 KIK48203.1 - 0.14 12.5 15.3 12 6.3 9.1 4.0 3 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KIK48203.1 - 0.62 9.9 9.7 57 3.6 0.2 6.0 6 0 0 6 6 6 0 zinc-finger C2H2-type zf_UBZ PF18439.1 KIK48203.1 - 1.6 8.4 7.2 1.2 8.8 0.3 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger CTP_transf_like PF01467.26 KIK48204.1 - 3.9e-17 62.8 0.1 5.8e-17 62.2 0.1 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like Lactamase_B PF00753.27 KIK48205.1 - 2e-09 37.7 0.6 3.4e-09 37.0 0.6 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIK48205.1 - 0.0058 16.2 0.0 0.009 15.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIK48206.1 - 4.7e-08 33.3 0.1 7.7e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIK48206.1 - 0.00093 18.8 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KIK48206.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Peptidase_M20 PF01546.28 KIK48207.1 - 3.2e-29 102.1 0.0 5.4e-29 101.4 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIK48207.1 - 1.9e-12 47.0 0.0 3.5e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain zf-C3HC4 PF00097.25 KIK48209.1 - 3.2e-09 36.5 2.1 1.1e-08 34.8 2.1 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 KIK48209.1 - 6e-09 35.5 36.0 5.2e-05 22.9 4.9 3.8 4 0 0 4 4 3 3 CCCH-type zinc finger zf-RING_2 PF13639.6 KIK48209.1 - 2.2e-08 34.3 5.6 2.2e-08 34.3 5.6 3.3 3 2 1 4 4 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIK48209.1 - 3.3e-08 33.2 6.3 3.3e-08 33.2 6.3 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK48209.1 - 6e-07 29.4 2.9 6e-07 29.4 2.9 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIK48209.1 - 7e-07 29.1 4.7 7e-07 29.1 4.7 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KIK48209.1 - 7.6e-07 28.9 2.1 7.6e-07 28.9 2.1 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 KIK48209.1 - 1.7e-06 27.8 24.6 0.0024 17.7 3.0 4.2 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIK48209.1 - 1.6e-05 24.8 8.6 1.6e-05 24.8 8.6 4.5 5 0 0 5 5 4 2 Zinc finger domain Torus PF16131.5 KIK48209.1 - 3.6e-05 24.4 13.9 0.0021 18.7 0.7 3.3 2 1 1 3 3 3 2 Torus domain Prok-RING_4 PF14447.6 KIK48209.1 - 0.00024 20.9 3.6 0.0014 18.4 3.6 2.3 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KIK48209.1 - 0.0012 19.0 5.9 0.0065 16.6 6.0 2.4 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KIK48209.1 - 0.0023 18.2 5.0 0.0023 18.2 5.0 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-CCCH_2 PF14608.6 KIK48209.1 - 0.0037 17.7 27.9 0.015 15.8 1.3 3.9 4 0 0 4 4 3 3 RNA-binding, Nab2-type zinc finger zf-RING_11 PF17123.5 KIK48209.1 - 0.086 12.6 2.5 0.37 10.6 2.5 2.2 1 1 0 1 1 1 0 RING-like zinc finger zf-CCCH_3 PF15663.5 KIK48209.1 - 0.94 9.7 10.5 0.28 11.4 6.5 2.1 2 1 0 2 2 2 0 Zinc-finger containing family FAD_binding_4 PF01565.23 KIK48210.1 - 2.6e-17 62.9 0.9 2.6e-17 62.9 0.9 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KIK48210.1 - 0.0011 19.0 0.1 0.0027 17.7 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like SAGA-Tad1 PF12767.7 KIK48212.1 - 5.1e-25 88.6 0.0 1.5e-24 87.0 0.0 1.7 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit WD40 PF00400.32 KIK48214.1 - 5.6e-27 93.4 2.9 6.1e-06 26.9 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK48214.1 - 9.3e-09 35.5 0.2 0.26 11.6 0.0 4.3 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK48214.1 - 1.5e-05 25.0 0.0 0.00086 19.2 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK48214.1 - 0.011 15.6 0.0 22 5.1 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIK48214.1 - 0.045 12.7 0.1 0.28 10.1 0.1 2.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KIK48214.1 - 0.054 12.4 0.1 0.73 8.7 0.0 2.3 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Ret2_MD PF18528.1 KIK48214.1 - 0.11 12.9 0.0 2.1 8.8 0.0 2.4 2 0 0 2 2 2 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Nup160 PF11715.8 KIK48214.1 - 0.16 10.6 0.1 0.18 10.4 0.1 1.3 1 1 0 1 1 1 0 Nucleoporin Nup120/160 GMC_oxred_N PF00732.19 KIK48215.1 - 1.3e-63 215.1 0.0 1.7e-63 214.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIK48215.1 - 1.4e-06 27.6 0.1 2.4e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIK48215.1 - 0.00017 20.8 0.3 0.069 12.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KIK48215.1 - 0.00098 18.4 0.2 0.0024 17.1 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KIK48215.1 - 0.02 14.1 0.0 0.045 13.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIK48215.1 - 0.14 10.8 1.7 0.16 10.6 0.6 1.6 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 KIK48215.1 - 1.4 8.4 4.5 0.81 9.2 0.4 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase Carn_acyltransf PF00755.20 KIK48217.1 - 4e-173 577.2 0.0 4.5e-173 577.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DnaJ-X PF14308.6 KIK48219.1 - 4.6e-65 219.0 4.8 2.3e-64 216.7 2.0 2.2 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KIK48219.1 - 5.9e-22 77.6 4.4 1.8e-21 76.0 4.4 1.9 1 0 0 1 1 1 1 DnaJ domain PspB PF06667.12 KIK48219.1 - 0.17 11.9 2.1 0.48 10.5 2.1 1.8 1 0 0 1 1 1 0 Phage shock protein B SabA_adhesion PF18304.1 KIK48219.1 - 0.18 11.0 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain SbsC_C PF18058.1 KIK48219.1 - 0.79 10.0 4.7 0.68 10.2 1.0 2.3 2 0 0 2 2 2 0 SbsC C-terminal domain CENP-Q PF13094.6 KIK48219.1 - 2.7 8.2 12.0 0.26 11.5 0.3 3.3 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit M20_dimer PF07687.14 KIK48220.1 - 2.5e-08 33.8 0.0 4.5e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain FAT PF02259.23 KIK48223.1 - 1.5e-121 405.8 9.2 2.2e-121 405.3 5.4 2.3 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KIK48223.1 - 1.8e-69 234.4 0.1 7.5e-69 232.3 0.1 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KIK48223.1 - 2.1e-55 187.0 2.2 4e-51 173.1 0.1 4.9 3 1 1 4 4 4 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KIK48223.1 - 3.8e-41 139.5 0.1 3.8e-41 139.5 0.1 4.3 5 0 0 5 5 4 1 FKBP12-rapamycin binding domain FATC PF02260.20 KIK48223.1 - 6.4e-15 54.7 0.9 1.8e-14 53.2 0.9 1.9 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 KIK48223.1 - 2.5e-13 50.2 23.2 8.6e-05 22.9 0.3 10.5 9 2 1 10 10 10 3 HEAT repeats HEAT PF02985.22 KIK48223.1 - 7.4e-12 44.5 15.5 0.0094 16.1 0.0 10.9 10 0 0 10 10 10 2 HEAT repeat Cnd1 PF12717.7 KIK48223.1 - 2.7e-08 34.0 3.1 0.03 14.4 0.1 5.4 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KIK48223.1 - 9.4e-08 32.4 31.9 5.9e-07 29.9 0.2 12.2 14 4 3 17 17 12 2 HEAT-like repeat CLASP_N PF12348.8 KIK48223.1 - 1.8e-07 31.0 2.5 0.23 11.0 0.0 5.5 4 1 1 5 5 5 2 CLASP N terminal TPR_19 PF14559.6 KIK48223.1 - 4.6e-07 30.2 3.5 0.0011 19.4 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat Vac14_Fab1_bd PF12755.7 KIK48223.1 - 6.1e-07 30.0 0.0 13 6.5 0.0 7.0 7 0 0 7 7 6 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KIK48223.1 - 0.0035 16.0 9.9 0.47 8.9 0.1 4.7 3 1 3 6 6 5 2 Adaptin N terminal region TPR_9 PF13371.6 KIK48223.1 - 0.019 15.1 2.0 1 9.6 0.0 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK48223.1 - 0.059 13.5 8.1 0.61 10.3 0.5 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIK48223.1 - 0.1 12.8 0.4 37 4.7 0.0 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KIK48223.1 - 0.11 12.8 0.9 38 4.7 0.2 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK48223.1 - 0.15 12.7 1.0 1.4 9.7 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat RTP1_C1 PF10363.9 KIK48223.1 - 0.2 11.8 2.6 43 4.3 0.0 5.1 5 0 0 5 5 4 0 Required for nuclear transport of RNA pol II C-terminus 1 TPR_7 PF13176.6 KIK48223.1 - 0.2 11.7 6.4 0.53 10.4 0.2 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat Cohesin_HEAT PF12765.7 KIK48223.1 - 0.26 11.6 2.0 2.4 8.5 0.1 3.7 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Xpo1 PF08389.12 KIK48223.1 - 0.37 10.8 2.6 34 4.5 0.0 4.9 5 1 0 5 5 3 0 Exportin 1-like protein TPR_1 PF00515.28 KIK48223.1 - 0.42 10.5 1.3 12 5.9 0.2 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat ParcG PF10274.9 KIK48223.1 - 6.2 6.9 7.7 5.1 7.2 0.0 4.4 4 1 1 5 5 5 0 Parkin co-regulated protein Actin PF00022.19 KIK48224.1 - 2.4e-28 98.9 0.0 7.1e-12 44.6 0.0 3.2 3 0 0 3 3 3 3 Actin Actin_micro PF17003.5 KIK48224.1 - 4.4e-09 36.0 0.0 8.6e-05 21.9 0.0 2.1 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 KIK48224.1 - 0.00015 20.7 0.1 0.0027 16.6 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein zf-C3HC4 PF00097.25 KIK48225.1 - 1.3e-06 28.2 10.6 2e-06 27.6 9.6 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK48225.1 - 1.5e-06 28.1 6.7 1.5e-06 28.1 6.7 2.7 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIK48225.1 - 0.00011 22.1 10.8 0.0012 18.8 5.2 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KIK48225.1 - 0.00019 21.5 12.6 0.0017 18.4 11.7 2.5 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KIK48225.1 - 0.00028 20.7 15.1 0.011 15.5 15.4 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK48225.1 - 0.0013 19.0 19.2 0.0018 18.6 17.2 2.3 1 1 1 2 2 2 1 Ring finger domain Tmpp129 PF10272.9 KIK48225.1 - 0.0085 15.4 10.1 0.0085 15.4 10.1 1.6 1 1 0 2 2 2 1 Putative transmembrane protein precursor U-box PF04564.15 KIK48225.1 - 0.028 14.6 0.0 0.067 13.4 0.0 1.7 1 0 0 1 1 1 0 U-box domain DUF1586 PF07625.11 KIK48225.1 - 0.12 12.4 1.6 0.5 10.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1586) zf-Nse PF11789.8 KIK48225.1 - 0.32 10.8 7.0 0.69 9.8 7.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KIK48225.1 - 0.4 10.6 15.1 2.2 8.2 7.6 3.1 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KIK48225.1 - 0.67 9.9 7.0 1.9 8.4 7.0 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KIK48225.1 - 6.3 6.9 10.2 24 5.1 9.9 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FOXP-CC PF16159.5 KIK48226.1 - 0.0013 19.3 0.3 0.0018 18.9 0.3 1.3 1 0 0 1 1 1 1 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KIK48226.1 - 0.033 14.5 0.0 0.034 14.4 0.0 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2 PF00096.26 KIK48226.1 - 0.082 13.4 0.6 0.14 12.6 0.6 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF2110 PF09883.9 KIK48226.1 - 0.11 12.1 0.0 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) zf_ZIC PF18366.1 KIK48226.1 - 0.13 12.4 0.8 0.13 12.4 0.8 2.0 2 1 0 2 2 2 0 Zic proteins zinc finger domain STAT1_TAZ2bind PF12162.8 KIK48226.1 - 0.29 10.8 0.5 4.7 6.9 0.0 2.2 2 0 0 2 2 2 0 STAT1 TAZ2 binding domain RCC1 PF00415.18 KIK48231.1 - 7.3e-15 55.3 8.5 0.0014 19.2 0.0 5.3 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KIK48231.1 - 4.1e-10 39.2 17.7 5.7e-05 22.8 0.2 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 KIK48231.1 - 0.0068 16.2 0.1 3.3 7.4 0.0 2.4 2 0 0 2 2 2 2 TUP1-like enhancer of split GST_N_3 PF13417.6 KIK48232.1 - 4.7e-11 42.9 0.0 1.2e-10 41.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK48232.1 - 2.6e-10 40.4 0.0 4.8e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIK48232.1 - 0.0003 20.9 0.0 0.00053 20.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK48232.1 - 0.0061 16.7 0.0 0.014 15.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK48232.1 - 0.033 14.2 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PAS_4 PF08448.10 KIK48232.1 - 0.035 14.3 0.0 0.056 13.7 0.0 1.3 1 0 0 1 1 1 0 PAS fold GST_N PF02798.20 KIK48232.1 - 0.12 12.8 0.0 18 5.8 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain PH_12 PF16457.5 KIK48235.1 - 2.9e-33 115.3 0.0 5.1e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 KIK48235.1 - 1.3e-24 86.9 0.0 3e-24 85.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.13 KIK48235.1 - 1.8e-23 83.6 0.0 2.9e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family Borrelia_orfA PF02414.15 KIK48235.1 - 0.03 14.0 1.7 0.047 13.3 1.7 1.2 1 0 0 1 1 1 0 Borrelia ORF-A MTHFR PF02219.17 KIK48236.1 - 1.2e-109 366.1 0.0 1.7e-109 365.6 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF202 PF02656.15 KIK48237.1 - 0.00022 21.6 3.2 0.00068 20.0 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Aa_trans PF01490.18 KIK48239.1 - 5.7e-75 252.6 27.3 6.7e-75 252.3 27.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SUZ PF12752.7 KIK48240.1 - 1.9e-12 47.8 8.2 1.9e-12 47.8 8.2 5.1 4 1 0 4 4 4 1 SUZ domain R3H PF01424.22 KIK48240.1 - 0.0016 18.4 0.0 0.0044 17.0 0.0 1.7 1 0 0 1 1 1 1 R3H domain RNA_pol_Rpb4 PF03874.16 KIK48241.1 - 2.1e-18 66.8 0.5 2.7e-18 66.5 0.5 1.2 1 1 0 1 1 1 1 RNA polymerase Rpb4 PseudoU_synth_1 PF01416.20 KIK48242.1 - 1.5e-07 31.8 0.0 9.9e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase FGGY_N PF00370.21 KIK48243.1 - 3.8e-24 85.6 0.0 2e-14 53.8 0.0 2.6 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KIK48243.1 - 2.2e-20 73.2 0.0 5.2e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4524 PF15025.6 KIK48244.1 - 0.008 15.9 1.1 1.1 9.0 0.1 2.2 1 1 0 2 2 2 2 Domain of unknown function (DUF4524) Sulfotransfer_4 PF17784.1 KIK48244.1 - 0.051 13.4 0.2 0.07 13.0 0.2 1.4 1 1 0 1 1 1 0 Sulfotransferase domain Coatomer_b_Cpla PF14806.6 KIK48244.1 - 0.072 13.1 0.1 1.7 8.6 0.0 2.0 1 1 1 2 2 2 0 Coatomer beta subunit appendage platform Pkinase PF00069.25 KIK48247.1 - 7.9e-72 241.8 0.0 1e-71 241.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK48247.1 - 3.2e-48 164.3 0.0 5e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KIK48247.1 - 3.8e-23 81.6 0.0 8.1e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 KIK48247.1 - 9.9e-06 24.6 0.0 1.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIK48247.1 - 0.0046 16.3 0.0 0.0074 15.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIK48247.1 - 0.032 13.6 0.0 0.077 12.3 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK48247.1 - 0.032 14.2 2.9 0.58 10.0 0.3 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF3915 PF13054.6 KIK48247.1 - 0.044 13.8 4.8 0.1 12.6 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DSHCT PF08148.12 KIK48247.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain DUF4707 PF15806.5 KIK48247.1 - 7.6 5.4 6.0 13 4.5 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4707) PI3_PI4_kinase PF00454.27 KIK48248.1 - 1.4e-54 185.5 0.1 2.8e-54 184.6 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KIK48248.1 - 3.5e-34 118.1 0.2 2.1e-33 115.6 0.2 2.6 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 KIK48248.1 - 2e-10 40.3 0.1 9.9e-10 38.1 0.0 2.2 2 0 0 2 2 2 1 FATC domain Acetyltransf_11 PF13720.6 KIK48248.1 - 0.061 13.8 0.1 0.32 11.5 0.1 2.3 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Cnd3 PF12719.7 KIK48248.1 - 0.082 12.1 0.0 0.32 10.2 0.0 2.1 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain PIF1 PF05970.14 KIK48249.1 - 6e-33 114.5 0.5 7.6e-33 114.2 0.5 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIK48249.1 - 2.5e-13 50.2 0.0 3.6e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK48249.1 - 6.3e-10 39.6 0.0 1.1e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK48249.1 - 1.1e-05 25.7 0.1 2.6e-05 24.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK48249.1 - 0.00033 21.1 0.1 0.00057 20.3 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KIK48249.1 - 0.0004 19.9 0.0 0.00089 18.8 0.0 1.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 KIK48249.1 - 0.00072 20.0 0.1 0.0013 19.2 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KIK48249.1 - 0.0044 17.0 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 KIK48249.1 - 0.0045 16.9 0.6 0.025 14.5 0.6 2.0 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea PhoH PF02562.16 KIK48249.1 - 0.0092 15.4 0.1 0.019 14.4 0.0 1.4 2 0 0 2 2 2 1 PhoH-like protein Viral_helicase1 PF01443.18 KIK48249.1 - 0.012 15.3 0.1 0.052 13.3 0.1 1.9 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KIK48249.1 - 0.049 13.2 0.3 0.095 12.2 0.3 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_5 PF07728.14 KIK48249.1 - 0.055 13.5 0.3 0.56 10.2 0.3 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KIK48249.1 - 0.058 13.8 0.1 0.12 12.7 0.1 1.7 1 1 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 KIK48249.1 - 0.067 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 KIK48249.1 - 0.068 13.2 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 KIK48249.1 - 0.078 12.2 0.1 0.14 11.4 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 KIK48249.1 - 0.11 12.5 0.1 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 NTPase Muraidase PF11860.8 KIK48249.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 N-acetylmuramidase AAA_24 PF13479.6 KIK48249.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIK48249.1 - 0.23 12.0 1.3 0.65 10.5 0.1 2.2 3 0 0 3 3 3 0 ABC transporter PIF1 PF05970.14 KIK48250.1 - 1.6e-13 50.6 0.0 2.2e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase SH3_13 PF18335.1 KIK48250.1 - 0.0027 17.5 0.0 0.006 16.4 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain F-box-like PF12937.7 KIK48252.1 - 1.6e-10 40.7 0.1 4.8e-10 39.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIK48252.1 - 0.38 11.2 6.5 1.4 9.5 0.9 4.4 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) NIF PF03031.18 KIK48253.1 - 1.3e-52 177.7 0.0 1.8e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Extensin-like_C PF06904.12 KIK48253.1 - 0.024 14.7 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 Extensin-like protein C-terminus HAD PF12710.7 KIK48253.1 - 0.063 13.7 0.1 0.46 10.9 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase EURL PF06937.11 KIK48253.1 - 0.092 12.2 2.8 0.15 11.5 2.8 1.2 1 0 0 1 1 1 0 EURL protein LCE PF14672.6 KIK48253.1 - 5.1 7.8 10.8 2 9.1 6.0 2.4 2 0 0 2 2 2 0 Late cornified envelope DUF3450 PF11932.8 KIK48256.1 - 4.7e-05 22.8 4.6 0.0001 21.7 4.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) ATG16 PF08614.11 KIK48256.1 - 7.4e-05 23.1 0.1 0.00016 22.0 0.1 1.6 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DivIC PF04977.15 KIK48256.1 - 0.00043 20.0 2.5 0.00072 19.3 1.1 2.0 2 0 0 2 2 2 1 Septum formation initiator DUF4407 PF14362.6 KIK48256.1 - 0.03 13.7 0.8 0.035 13.5 0.0 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4407) ERM PF00769.19 KIK48256.1 - 0.036 13.9 1.3 0.084 12.7 1.3 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family NRBF2 PF08961.10 KIK48256.1 - 0.041 13.5 0.8 0.041 13.5 0.8 2.0 2 1 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Cnn_1N PF07989.11 KIK48256.1 - 0.06 13.5 2.8 4 7.7 3.1 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Nup54 PF13874.6 KIK48256.1 - 0.062 13.4 2.4 0.13 12.3 2.4 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 HsbA PF12296.8 KIK48256.1 - 0.12 12.8 3.7 0.37 11.2 3.7 1.8 1 1 0 1 1 1 0 Hydrophobic surface binding protein A Sec34 PF04136.15 KIK48256.1 - 0.13 12.1 3.1 0.19 11.6 1.6 2.1 1 1 1 2 2 2 0 Sec34-like family DUF4140 PF13600.6 KIK48256.1 - 0.2 12.1 3.4 4.3 7.8 0.0 3.1 4 0 0 4 4 3 0 N-terminal domain of unknown function (DUF4140) CorA PF01544.18 KIK48256.1 - 0.24 10.7 1.7 1 8.6 0.2 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF5446 PF17522.2 KIK48256.1 - 0.27 11.4 2.5 0.94 9.7 1.6 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5446) HALZ PF02183.18 KIK48256.1 - 0.38 11.0 1.9 0.86 9.9 0.4 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Fez1 PF06818.15 KIK48256.1 - 0.38 11.2 3.8 0.23 11.9 1.7 1.7 2 0 0 2 2 1 0 Fez1 DUF1664 PF07889.12 KIK48256.1 - 0.42 10.6 2.5 3.7 7.6 2.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) LPP PF04728.13 KIK48256.1 - 0.61 10.5 9.4 4 7.9 0.5 3.1 3 0 0 3 3 3 0 Lipoprotein leucine-zipper PCRF PF03462.18 KIK48256.1 - 0.92 9.3 4.8 6.7 6.5 1.7 2.2 2 0 0 2 2 2 0 PCRF domain ADIP PF11559.8 KIK48256.1 - 0.98 9.5 10.0 2.5 8.2 2.7 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 KIK48256.1 - 1.1 8.1 6.7 0.23 10.3 3.2 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein ZapB PF06005.12 KIK48256.1 - 1.2 9.6 4.5 3.9 8.0 1.1 2.4 1 1 1 2 2 2 0 Cell division protein ZapB CENP-H PF05837.12 KIK48256.1 - 1.4 9.3 6.8 0.96 9.9 2.6 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) NPV_P10 PF05531.12 KIK48256.1 - 1.8 9.1 7.9 4.6 7.8 1.8 2.7 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.12 KIK48256.1 - 1.8 8.6 9.9 0.33 11.0 0.7 2.6 2 1 0 2 2 1 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.6 KIK48256.1 - 2.4 8.6 5.7 1.7 9.1 3.0 2.1 2 1 0 2 2 1 0 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.12 KIK48256.1 - 4.7 7.3 6.9 52 3.9 6.9 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus YscO PF07321.12 KIK48256.1 - 5.5 6.9 10.8 2 8.3 6.3 2.3 2 1 1 3 3 3 0 Type III secretion protein YscO SlyX PF04102.12 KIK48256.1 - 6.2 7.5 7.7 20 5.9 1.4 2.6 1 1 1 2 2 2 0 SlyX HAUS5 PF14817.6 KIK48256.1 - 6.8 5.3 9.6 0.7 8.6 1.4 2.5 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 5 Tropomyosin_1 PF12718.7 KIK48256.1 - 7.4 6.7 9.1 1.1e+02 3.0 8.9 2.2 1 1 0 1 1 1 0 Tropomyosin like DUF676 PF05057.14 KIK48257.1 - 1.1e-40 139.5 0.0 1.7e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 KIK48257.1 - 0.00021 21.2 0.0 0.00043 20.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Palm_thioest PF02089.15 KIK48257.1 - 0.00041 20.3 0.0 0.00061 19.7 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KIK48257.1 - 0.18 11.5 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein An_peroxidase PF03098.15 KIK48261.1 - 9e-39 133.4 0.1 1.2e-27 96.7 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KIK48261.1 - 1.8e-09 36.9 0.0 2.7e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 Cytochrome P450 Coatomer_E PF04733.14 KIK48262.1 - 1.4e-29 103.5 0.0 1.6e-29 103.2 0.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KIK48262.1 - 0.00026 21.4 13.6 0.0092 16.5 4.0 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIK48262.1 - 0.0013 19.4 9.3 1.1 10.0 1.9 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK48262.1 - 0.0018 19.0 15.5 0.41 11.6 1.5 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIK48262.1 - 0.055 14.1 0.3 50 4.8 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK48262.1 - 0.11 12.8 0.2 5.5 7.5 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIK48262.1 - 5.6 7.9 13.5 7.1 7.6 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat PALP PF00291.25 KIK48263.1 - 6.2e-54 183.4 0.2 7.1e-54 183.2 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DOPA_dioxygen PF08883.11 KIK48264.1 - 1.2e-39 134.7 0.2 1.6e-39 134.4 0.2 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DOPA_dioxygen PF08883.11 KIK48265.1 - 1e-42 144.6 0.4 1.3e-42 144.4 0.4 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family dsrm PF00035.26 KIK48266.1 - 0.0013 19.4 1.1 0.071 13.8 0.0 3.7 4 0 0 4 4 4 1 Double-stranded RNA binding motif DUF4100 PF13352.6 KIK48266.1 - 0.63 9.8 2.2 1 9.1 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) PH_10 PF15411.6 KIK48268.1 - 9.4e-24 84.0 0.0 1.7e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_UBOX PF13445.6 KIK48268.1 - 3.4e-05 23.8 1.3 8.8e-05 22.4 1.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIK48268.1 - 6e-05 23.3 1.7 0.00014 22.1 1.8 1.7 1 1 0 1 1 1 1 Ring finger domain VWA_3 PF13768.6 KIK48268.1 - 0.00017 21.6 0.0 0.00066 19.7 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_5 PF14634.6 KIK48268.1 - 0.00042 20.2 0.5 0.00099 19.0 0.6 1.6 1 1 0 1 1 1 1 zinc-RING finger domain VWA PF00092.28 KIK48268.1 - 0.001 19.3 0.0 0.0026 18.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_11 PF17123.5 KIK48268.1 - 0.21 11.4 2.5 0.71 9.7 2.5 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 KIK48268.1 - 0.23 11.4 3.2 1.3 8.9 3.2 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 KIK48268.1 - 0.47 10.4 1.9 0.66 9.9 0.4 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Dynactin_p22 PF07426.11 KIK48269.1 - 8e-12 45.3 0.7 1.8e-11 44.2 0.1 1.9 2 1 0 2 2 2 1 Dynactin subunit p22 GAT PF03127.14 KIK48269.1 - 0.07 13.5 0.3 1.8 8.9 0.1 2.6 2 0 0 2 2 2 0 GAT domain HET PF06985.11 KIK48270.1 - 5.9e-14 52.7 3.1 5.5e-11 43.0 0.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) E1-E2_ATPase PF00122.20 KIK48271.1 - 2.1e-47 161.0 2.4 2.1e-47 161.0 2.4 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KIK48271.1 - 1.3e-31 110.5 1.5 1.6e-31 110.2 0.4 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KIK48271.1 - 6e-29 100.3 0.0 7.7e-14 51.9 0.0 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KIK48271.1 - 0.00021 21.1 1.1 0.026 14.2 0.5 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Vps5 PF09325.10 KIK48273.1 - 5.5e-64 215.9 9.5 1e-63 215.0 9.5 1.5 1 1 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KIK48273.1 - 2.2e-26 92.1 0.2 7e-26 90.4 0.0 1.9 2 0 0 2 2 2 1 PX domain BAR PF03114.18 KIK48273.1 - 0.0034 17.1 4.0 0.0052 16.5 4.0 1.2 1 0 0 1 1 1 1 BAR domain BAR_3_WASP_bdg PF10456.9 KIK48273.1 - 0.0053 16.2 3.9 0.25 10.8 3.9 2.2 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein DUF724 PF05266.14 KIK48273.1 - 0.13 12.1 2.4 0.22 11.3 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PX PF00787.24 KIK48274.1 - 9.2e-18 64.3 0.4 1.9e-17 63.2 0.0 1.7 2 0 0 2 2 2 1 PX domain DUF4043 PF13252.6 KIK48274.1 - 0.18 10.9 0.2 4.5 6.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4043) PMT PF02366.18 KIK48275.1 - 1.8e-82 276.6 17.1 3.9e-82 275.5 17.1 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KIK48275.1 - 4.1e-63 212.6 3.5 4.1e-63 212.6 3.5 3.3 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KIK48275.1 - 2e-15 57.1 3.2 4.1e-15 56.1 3.2 1.5 1 1 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KIK48275.1 - 3.4e-05 24.1 12.9 3.4e-05 24.1 12.9 2.4 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Ion_trans PF00520.31 KIK48276.1 - 8e-05 22.0 23.5 0.00019 20.8 23.5 1.6 1 1 0 1 1 1 1 Ion transport protein OmdA PF13376.6 KIK48276.1 - 0.1 12.6 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated LANC_like PF05147.13 KIK48276.1 - 0.16 10.5 0.0 0.28 9.7 0.0 1.3 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein PKD_channel PF08016.12 KIK48276.1 - 0.95 8.1 15.8 1.5 7.4 0.2 2.2 2 0 0 2 2 2 0 Polycystin cation channel Ank_2 PF12796.7 KIK48277.1 - 2.3e-11 44.1 0.0 5.5e-06 26.9 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KIK48277.1 - 4.3e-09 36.4 0.5 0.0013 19.1 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KIK48277.1 - 1e-07 31.6 0.0 0.13 12.9 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KIK48277.1 - 5.7e-06 26.8 0.3 0.014 16.0 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIK48277.1 - 9.4e-06 25.8 0.4 0.13 12.7 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) KilA-N PF04383.13 KIK48277.1 - 0.0028 17.5 0.1 0.083 12.7 0.1 2.4 1 1 0 1 1 1 1 KilA-N domain DUF3562 PF12085.8 KIK48277.1 - 0.02 14.5 0.0 0.059 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) HrpB7 PF09486.10 KIK48277.1 - 0.034 14.6 1.3 0.069 13.5 1.3 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Filament PF00038.21 KIK48277.1 - 0.036 13.7 0.4 0.059 13.0 0.4 1.2 1 0 0 1 1 1 0 Intermediate filament protein WD40 PF00400.32 KIK48278.1 - 7.9e-42 140.5 9.2 3.4e-07 30.9 0.1 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK48278.1 - 1.6e-15 57.2 0.0 0.032 14.5 0.0 6.5 4 2 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 KIK48278.1 - 3.4e-13 48.9 1.0 6.5e-13 48.0 1.0 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like WD40_like PF17005.5 KIK48278.1 - 0.00019 20.9 0.0 0.14 11.4 0.0 2.6 1 1 1 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 KIK48278.1 - 0.00066 18.7 0.0 14 4.5 0.0 4.1 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIK48278.1 - 0.00081 18.8 0.1 12 5.1 0.0 3.4 3 0 0 3 3 3 3 Neuroblastoma-amplified sequence, N terminal Pkinase PF00069.25 KIK48279.1 - 1.4e-60 204.9 0.0 1e-59 202.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK48279.1 - 1.2e-24 87.1 0.3 1.3e-18 67.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK48279.1 - 1.1e-05 24.6 0.1 1.5e-05 24.1 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KIK48279.1 - 0.00097 18.5 1.4 0.0028 17.0 0.1 2.3 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIK48279.1 - 0.0015 18.0 1.9 0.014 14.8 0.3 2.7 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 KIK48279.1 - 0.0025 17.8 0.3 0.19 11.6 0.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KIK48279.1 - 0.0026 16.8 0.1 0.0044 16.1 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 KIK48279.1 - 0.03 13.9 1.6 0.16 11.5 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 KIK48279.1 - 0.29 9.9 7.2 1 8.1 7.2 2.0 1 1 0 1 1 1 0 Fungal protein kinase ADH_N PF08240.12 KIK48280.1 - 2.5e-26 91.7 1.5 2.5e-26 91.7 1.5 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIK48280.1 - 3.3e-18 65.9 0.0 4.7e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIK48280.1 - 6.2e-05 22.6 0.2 0.00054 19.5 0.2 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus PET117 PF15786.5 KIK48281.1 - 1.5e-23 82.8 1.5 1.7e-23 82.6 1.5 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial MAS20 PF02064.15 KIK48281.1 - 0.044 13.9 1.5 0.053 13.6 1.5 1.0 1 0 0 1 1 1 0 MAS20 protein import receptor CTD_bind PF04818.13 KIK48282.1 - 5.3e-06 27.2 0.0 1.5e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Methyltransf_23 PF13489.6 KIK48283.1 - 8e-22 77.8 0.0 1.1e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK48283.1 - 3.9e-21 75.5 0.0 6.4e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK48283.1 - 1.8e-16 60.6 0.0 3.3e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK48283.1 - 1.9e-14 54.2 0.0 3e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK48283.1 - 3e-12 46.6 0.0 5.1e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KIK48283.1 - 5.8e-10 38.9 0.0 8.1e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KIK48283.1 - 1.9e-07 30.3 0.0 2.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 KIK48283.1 - 6.1e-06 25.8 0.0 8.6e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KIK48283.1 - 0.00034 20.0 0.0 0.00048 19.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KIK48283.1 - 0.00074 19.1 0.0 0.0014 18.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KIK48283.1 - 0.0062 16.5 0.0 0.0095 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KIK48283.1 - 0.023 14.3 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) MetW PF07021.12 KIK48283.1 - 0.025 14.2 0.2 0.048 13.2 0.2 1.5 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW TPMT PF05724.11 KIK48283.1 - 0.071 12.8 0.0 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) AdoMet_MTase PF07757.13 KIK48283.1 - 0.19 12.1 0.1 0.36 11.2 0.1 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase TelA PF05816.11 KIK48284.1 - 0.00096 18.3 0.1 0.0027 16.8 0.0 1.6 1 1 0 1 1 1 1 Toxic anion resistance protein (TelA) CCDC144C PF14915.6 KIK48284.1 - 0.0028 16.8 6.5 0.0038 16.4 6.5 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region RPW8 PF05659.11 KIK48284.1 - 0.003 17.2 1.0 0.37 10.5 0.2 2.1 1 1 1 2 2 2 2 Arabidopsis broad-spectrum mildew resistance protein RPW8 AAA_32 PF13654.6 KIK48284.1 - 0.0035 16.2 0.7 0.0043 15.9 0.7 1.0 1 0 0 1 1 1 1 AAA domain Spc7 PF08317.11 KIK48284.1 - 0.015 14.2 2.5 0.018 13.9 2.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Neur_chan_memb PF02932.16 KIK48284.1 - 0.13 12.3 2.1 0.18 11.9 2.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tropomyosin_1 PF12718.7 KIK48284.1 - 0.13 12.4 4.3 0.16 12.1 3.8 1.3 1 1 0 1 1 1 0 Tropomyosin like Fib_alpha PF08702.10 KIK48284.1 - 0.18 12.0 3.2 0.25 11.5 3.2 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Sec34 PF04136.15 KIK48284.1 - 0.21 11.5 3.3 2.4 8.0 0.4 2.1 1 1 1 2 2 2 0 Sec34-like family KxDL PF10241.9 KIK48284.1 - 0.41 11.0 3.6 2.3 8.6 0.0 2.5 1 1 0 2 2 2 0 Uncharacterized conserved protein DUF1664 PF07889.12 KIK48284.1 - 0.43 10.6 3.3 0.61 10.1 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SnoaL_2 PF12680.7 KIK48285.1 - 0.007 17.0 0.2 0.017 15.7 0.1 1.6 1 1 1 2 2 2 1 SnoaL-like domain Glyco_hydro_18 PF00704.28 KIK48287.1 - 2.2e-14 53.9 2.3 3.1e-14 53.4 2.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 NARG2_C PF10505.9 KIK48287.1 - 0.2 11.2 0.0 1.2 8.6 0.0 1.9 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus Glyco_hydro_18 PF00704.28 KIK48289.1 - 9.8e-13 48.5 1.9 1.4e-12 48.0 1.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 NARG2_C PF10505.9 KIK48289.1 - 0.18 11.3 0.0 0.73 9.3 0.0 1.8 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus DUF685 PF05085.12 KIK48290.1 - 0.11 11.7 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF685) KAR9 PF08580.10 KIK48291.1 - 4.5e-06 25.5 77.8 4.5e-06 25.5 77.8 6.2 1 1 1 3 3 3 1 Yeast cortical protein KAR9 GAS2 PF02187.17 KIK48291.1 - 7.8e-05 22.7 0.1 0.00021 21.3 0.1 1.7 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Cauli_AT PF03233.13 KIK48291.1 - 0.092 12.7 1.1 6.7 6.6 0.2 2.5 2 0 0 2 2 2 0 Aphid transmission protein Clr2_transil PF16761.5 KIK48292.1 - 6.2e-25 87.8 0.3 1.2e-24 86.9 0.3 1.5 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 KIK48292.1 - 4.8e-10 40.4 0.0 1.9e-05 25.5 0.0 2.5 2 0 0 2 2 2 2 Transcription-silencing protein Clr2 COX6C PF02937.15 KIK48293.1 - 0.0062 16.6 0.0 0.0069 16.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc DUF2878 PF11086.8 KIK48293.1 - 0.075 13.2 0.1 0.085 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2878) WD40 PF00400.32 KIK48294.1 - 1.2e-09 38.6 4.1 0.39 11.7 0.2 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat BRCT PF00533.26 KIK48294.1 - 0.041 14.3 0.2 2.8 8.4 0.0 3.0 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain MFS_1 PF07690.16 KIK48295.1 - 1.5e-16 60.3 62.1 2.3e-15 56.4 33.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK48295.1 - 0.014 14.3 25.5 0.04 12.8 25.5 1.7 1 1 0 1 1 1 0 Sugar (and other) transporter OSTbeta PF15048.6 KIK48295.1 - 0.054 13.6 0.0 0.094 12.9 0.0 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein BTB PF00651.31 KIK48296.1 - 2.1e-08 34.4 0.0 9.6e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain TPR_16 PF13432.6 KIK48298.1 - 1.1e-06 29.1 1.8 0.00011 22.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK48298.1 - 4.1e-06 26.5 0.3 0.8 10.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIK48298.1 - 1.1e-05 25.8 0.1 0.00093 19.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK48298.1 - 0.0007 19.5 0.1 4.6 7.5 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIK48298.1 - 0.0033 18.1 7.8 6.2 7.9 0.0 4.7 3 2 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIK48298.1 - 0.0086 16.2 0.0 1.4 9.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIK48298.1 - 0.013 15.8 0.4 0.066 13.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIK48298.1 - 0.091 12.7 2.6 0.47 10.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIK48298.1 - 0.22 11.3 0.4 15 5.4 0.0 3.0 2 1 1 3 3 3 0 TPR repeat RNA_pol_Rpb5_N PF03871.14 KIK48300.1 - 0.13 12.9 0.0 0.21 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain MBOAT PF03062.19 KIK48302.1 - 5.7e-35 121.3 16.3 5.7e-35 121.3 16.3 2.7 2 2 1 3 3 3 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KIK48302.1 - 9.6e-05 22.6 3.5 9.6e-05 22.6 3.5 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family dCMP_cyt_deam_1 PF00383.23 KIK48303.1 - 3.6e-22 78.1 0.2 5.3e-22 77.6 0.2 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KIK48303.1 - 8.4e-22 77.4 0.2 1.4e-21 76.7 0.2 1.4 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KIK48303.1 - 0.0019 18.3 1.3 0.0063 16.6 1.3 1.8 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 KIK48303.1 - 0.0088 16.2 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 KIK48303.1 - 0.086 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 APOBEC2 APOBEC3 PF18771.1 KIK48303.1 - 0.17 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 APOBEC3 Peptidase_S9_N PF02897.15 KIK48304.1 - 1.4e-93 314.0 3.7 1.9e-93 313.5 3.7 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 KIK48304.1 - 3.1e-47 160.8 0.0 5.9e-47 159.9 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family RED_N PF07808.13 KIK48306.1 - 1.8e-16 60.5 8.9 1.8e-16 60.5 8.9 2.7 3 0 0 3 3 3 1 RED-like protein N-terminal region MMgT PF10270.9 KIK48307.1 - 7.9e-17 61.4 0.0 9.4e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter MFS_1 PF07690.16 KIK48308.1 - 3.9e-32 111.6 36.8 6.2e-32 110.9 36.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK48308.1 - 0.00021 19.9 1.6 0.00021 19.9 1.6 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) C_GCAxxG_C_C PF09719.10 KIK48308.1 - 1.7 8.9 4.8 1.2 9.4 2.3 1.9 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) UNC-93 PF05978.16 KIK48308.1 - 6.6 6.4 12.8 2.3 7.9 1.7 3.4 2 1 1 3 3 3 0 Ion channel regulatory protein UNC-93 Zw10 PF06248.13 KIK48309.1 - 8.8e-15 54.3 0.0 2.3e-14 52.9 0.0 1.6 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 KIK48309.1 - 2.2e-09 37.3 0.0 4.6e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal MutL_C PF08676.11 KIK48309.1 - 0.028 14.2 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 MutL C terminal dimerisation domain Phasin_2 PF09361.10 KIK48309.1 - 0.17 12.2 1.2 12 6.2 0.0 3.0 3 0 0 3 3 3 0 Phasin protein Rep_fac_C PF08542.11 KIK48310.1 - 2.1e-20 72.9 0.0 1.1e-19 70.6 0.0 2.3 3 0 0 3 3 1 1 Replication factor C C-terminal domain AAA PF00004.29 KIK48310.1 - 6.5e-18 65.4 0.0 1.2e-17 64.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KIK48310.1 - 6.4e-15 55.3 0.0 5.7e-11 42.5 0.1 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 KIK48310.1 - 8.9e-08 32.3 0.0 3.9e-07 30.2 0.0 2.0 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 KIK48310.1 - 3.3e-07 30.2 0.0 1.2e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.13 KIK48310.1 - 4.9e-06 26.4 0.3 1.1e-05 25.3 0.3 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 KIK48310.1 - 5.3e-06 26.5 0.1 1.2e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KIK48310.1 - 7.2e-06 26.2 0.1 2.6e-05 24.5 0.1 2.0 1 1 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 KIK48310.1 - 1.2e-05 25.3 0.0 4.1e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KIK48310.1 - 1.7e-05 24.1 0.0 2.5e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 KIK48310.1 - 4.7e-05 23.8 0.0 8.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KIK48310.1 - 9e-05 22.8 0.9 0.032 14.6 0.0 2.7 2 1 1 3 3 3 2 AAA domain DEAD PF00270.29 KIK48310.1 - 0.00011 22.0 0.6 0.00037 20.3 0.6 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIK48310.1 - 0.00012 22.2 0.1 0.022 14.7 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIK48310.1 - 0.00018 21.8 0.5 0.15 12.3 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_24 PF13479.6 KIK48310.1 - 0.00025 20.8 0.0 0.00053 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KIK48310.1 - 0.00033 20.4 0.2 0.0007 19.4 0.0 1.8 2 1 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KIK48310.1 - 0.00055 19.9 0.3 0.0071 16.3 0.1 2.7 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KIK48310.1 - 0.00091 19.1 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIK48310.1 - 0.0026 17.3 0.0 0.0055 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 KIK48310.1 - 0.0042 16.5 0.1 0.14 11.6 0.0 2.2 1 1 1 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 KIK48310.1 - 0.0064 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein PIF1 PF05970.14 KIK48310.1 - 0.012 14.8 0.2 1.2 8.2 0.1 2.2 1 1 1 2 2 2 0 PIF1-like helicase Viral_helicase1 PF01443.18 KIK48310.1 - 0.016 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.13 KIK48310.1 - 0.025 13.8 0.0 0.053 12.7 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain MCM PF00493.23 KIK48310.1 - 0.029 13.5 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain Mg_chelatase PF01078.21 KIK48310.1 - 0.033 13.6 0.0 0.3 10.5 0.0 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KIK48310.1 - 0.034 14.4 0.1 0.071 13.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain Methyltransf_31 PF13847.6 KIK48310.1 - 0.035 13.9 0.3 0.15 11.9 0.3 2.0 1 1 0 1 1 1 0 Methyltransferase domain SNF2_N PF00176.23 KIK48310.1 - 0.043 12.5 0.0 0.083 11.6 0.0 1.5 1 0 0 1 1 1 0 SNF2 family N-terminal domain TPR_6 PF13174.6 KIK48310.1 - 0.048 14.3 0.7 2.5 8.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat ATPase_2 PF01637.18 KIK48310.1 - 0.084 12.8 0.1 0.18 11.7 0.1 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KIK48310.1 - 0.1 13.1 0.0 0.25 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 KIK48310.1 - 0.11 11.6 0.1 0.41 9.7 0.0 1.7 1 1 0 2 2 2 0 Type II/IV secretion system protein ubiquitin PF00240.23 KIK48311.1 - 3.4e-34 116.4 0.5 3.4e-34 116.4 0.5 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 KIK48311.1 - 7.6e-27 93.2 3.7 7.6e-27 93.2 3.7 1.9 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KIK48311.1 - 3.5e-16 58.8 0.6 7.9e-16 57.7 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KIK48311.1 - 2.8e-05 24.5 0.4 0.00014 22.2 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIK48311.1 - 0.00029 20.9 0.5 0.00065 19.8 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KIK48311.1 - 0.0071 16.7 1.0 0.012 15.9 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KIK48311.1 - 0.0073 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KIK48311.1 - 0.0079 16.7 0.8 0.011 16.3 0.8 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KIK48311.1 - 0.02 14.9 1.1 5.9 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 KIK48311.1 - 0.031 14.5 0.6 0.053 13.8 0.6 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF4925 PF16272.5 KIK48311.1 - 0.071 12.6 0.2 0.1 12.1 0.2 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4925) TFIIS_M PF07500.14 KIK48313.1 - 1.2e-17 64.4 0.9 1.2e-17 64.4 0.9 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 KIK48313.1 - 2e-10 40.8 0.0 3.6e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 KIK48313.1 - 1.9e-07 30.9 11.2 3.9e-07 29.9 11.2 1.5 1 0 0 1 1 1 1 PHD-finger DUF3915 PF13054.6 KIK48313.1 - 2.2 8.3 7.9 6.4 6.8 7.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Pkinase PF00069.25 KIK48314.1 - 4.3e-73 245.9 0.0 5.7e-73 245.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK48314.1 - 1.3e-53 182.0 0.0 1.9e-53 181.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KIK48314.1 - 1.4e-07 31.3 1.7 2.8e-07 30.3 1.7 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 KIK48314.1 - 0.00031 20.3 1.5 0.00067 19.2 1.5 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Kinase-like PF14531.6 KIK48314.1 - 0.00053 19.4 0.1 0.0092 15.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like C1_2 PF03107.16 KIK48314.1 - 0.025 14.9 2.0 0.058 13.7 2.0 1.6 1 0 0 1 1 1 0 C1 domain PHD PF00628.29 KIK48314.1 - 0.05 13.5 3.9 0.12 12.3 3.9 1.6 1 0 0 1 1 1 0 PHD-finger RIO1 PF01163.22 KIK48314.1 - 0.056 13.0 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 RIO1 family F-box-like PF12937.7 KIK48315.1 - 2.6e-06 27.2 0.4 5.7e-06 26.1 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK48315.1 - 3e-05 23.8 0.1 5.1e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 F-box domain MIT PF04212.18 KIK48315.1 - 0.0049 16.9 0.0 0.0089 16.1 0.0 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 KIK48315.1 - 0.026 14.2 0.4 0.14 11.9 0.1 2.0 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.17 KIK48315.1 - 0.079 13.1 0.6 0.23 11.7 0.4 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK48315.1 - 0.094 13.6 1.1 0.47 11.4 0.8 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat F-box_4 PF15966.5 KIK48315.1 - 0.13 12.2 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 F-box TPR_1 PF00515.28 KIK48315.1 - 0.14 12.0 0.1 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat ASD1 PF08688.10 KIK48315.1 - 0.21 12.0 1.2 0.37 11.2 1.2 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD1 DnaJ PF00226.31 KIK48316.1 - 2.9e-25 88.1 0.5 5.4e-25 87.3 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 KIK48316.1 - 1.3e-24 86.4 0.0 2.6e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) TPR_2 PF07719.17 KIK48316.1 - 0.062 13.4 0.0 2.9 8.2 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIK48316.1 - 0.095 12.6 0.1 3.3 7.7 0.0 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat SSP160 PF06933.11 KIK48316.1 - 1.4 7.1 10.2 1.9 6.6 10.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-NADH-PPase PF09297.11 KIK48317.1 - 0.12 12.0 0.2 0.26 11.0 0.2 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Patatin PF01734.22 KIK48317.1 - 0.14 12.3 3.2 3 8.0 0.1 2.6 3 0 0 3 3 3 0 Patatin-like phospholipase Phage_holin_7_1 PF16081.5 KIK48317.1 - 0.36 11.0 3.6 0.31 11.2 0.2 2.5 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Borealin PF10512.9 KIK48317.1 - 2.3 8.2 9.0 0.055 13.4 0.6 2.6 3 0 0 3 3 3 0 Cell division cycle-associated protein 8 ERG4_ERG24 PF01222.17 KIK48318.1 - 7.2e-129 430.3 25.1 8.3e-129 430.1 25.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 KIK48318.1 - 0.0078 16.6 0.5 0.032 14.6 0.1 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.12 KIK48318.1 - 0.037 13.5 11.8 0.084 12.4 11.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) DWNN PF08783.11 KIK48319.1 - 7e-32 109.6 1.7 9.8e-32 109.1 0.6 1.9 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 KIK48319.1 - 1.6e-10 40.6 6.5 1.6e-10 40.6 6.5 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 KIK48319.1 - 4e-06 26.7 1.6 4e-06 26.7 1.6 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4_2 PF13923.6 KIK48319.1 - 0.0017 18.2 7.7 0.0017 18.2 7.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.6 KIK48319.1 - 0.008 16.1 0.3 0.008 16.1 0.3 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 KIK48319.1 - 0.013 15.2 6.3 0.03 14.0 0.5 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-C3HC4_3 PF13920.6 KIK48319.1 - 0.017 14.9 5.5 0.017 14.9 5.5 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Trm112p PF03966.16 KIK48319.1 - 0.056 14.0 0.1 0.31 11.7 0.3 2.1 2 0 0 2 2 1 0 Trm112p-like protein zf-RING_UBOX PF13445.6 KIK48319.1 - 0.062 13.3 6.5 0.15 12.1 6.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf_UBZ PF18439.1 KIK48319.1 - 0.37 10.4 0.1 0.37 10.4 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-RING_5 PF14634.6 KIK48319.1 - 0.57 10.2 12.8 0.063 13.2 6.9 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 KIK48319.1 - 0.57 10.1 8.1 1.3 9.0 8.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK48319.1 - 0.59 10.3 8.0 1.6 9.0 8.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KIK48319.1 - 0.69 9.8 3.8 1.5 8.7 3.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TFIIA PF03153.13 KIK48319.1 - 1.3 8.9 23.6 0.36 10.8 19.2 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-RING_2 PF13639.6 KIK48319.1 - 3.3 8.1 13.2 0.073 13.4 6.7 1.7 2 0 0 2 2 1 0 Ring finger domain zinc-ribbons_6 PF07191.12 KIK48319.1 - 3.4 7.7 7.9 4.4 7.4 3.6 2.4 2 0 0 2 2 2 0 zinc-ribbons SLATT_fungal PF18142.1 KIK48320.1 - 3.4e-43 146.4 0.4 4.8e-43 146.0 0.4 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain FerA PF08165.11 KIK48320.1 - 0.0094 15.9 0.2 0.032 14.2 0.0 1.9 2 0 0 2 2 2 1 FerA (NUC095) domain Npa1 PF11707.8 KIK48320.1 - 0.022 14.1 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal SLATT_1 PF18181.1 KIK48320.1 - 0.21 11.5 0.8 0.34 10.8 0.8 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 SNF2_N PF00176.23 KIK48321.1 - 3.2e-17 62.3 3.5 3e-10 39.4 0.0 2.8 3 0 0 3 3 3 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 KIK48321.1 - 1.6e-11 44.2 0.1 4.1e-10 39.5 0.0 2.8 3 0 0 3 3 3 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 KIK48321.1 - 7.4e-05 23.1 0.0 0.00021 21.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK48321.1 - 0.014 15.4 0.7 0.07 13.1 0.0 2.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit GcpE PF04551.14 KIK48321.1 - 0.11 11.6 0.2 1.6 7.7 0.0 2.2 2 0 0 2 2 2 0 GcpE protein A2L_zn_ribbon PF08792.10 KIK48321.1 - 0.21 11.4 6.0 0.58 9.9 6.0 1.9 1 0 0 1 1 1 0 A2L zinc ribbon domain Prok-RING_4 PF14447.6 KIK48321.1 - 0.32 10.9 3.4 1.1 9.1 3.4 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KIK48321.1 - 9.5 6.3 15.3 0.16 12.0 6.2 2.7 2 0 0 2 2 2 0 zinc-RING finger domain PadR PF03551.14 KIK48322.1 - 0.039 13.9 0.0 0.043 13.8 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PET PF06297.14 KIK48323.1 - 0.075 13.4 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 PET Domain Cript PF10235.9 KIK48324.1 - 3.4e-28 98.0 4.5 3.4e-28 98.0 4.5 1.5 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 KIK48324.1 - 0.0011 18.9 10.4 0.0021 18.0 6.2 2.2 1 1 0 2 2 2 1 Double zinc ribbon Rhodanese_C PF12368.8 KIK48324.1 - 0.019 15.3 6.1 0.038 14.4 1.9 2.2 2 0 0 2 2 2 0 Rhodanase C-terminal zinc_ribbon_2 PF13240.6 KIK48324.1 - 0.02 14.6 14.0 3.9 7.3 0.0 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Gin PF10764.9 KIK48324.1 - 0.13 12.3 7.6 0.85 9.6 0.0 3.1 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin zf_UBZ PF18439.1 KIK48324.1 - 0.24 11.0 8.8 1.9 8.1 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF2039 PF10217.9 KIK48324.1 - 0.43 10.9 16.7 3.5 8.0 16.7 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) DUF1272 PF06906.11 KIK48324.1 - 0.44 10.7 6.3 0.5 10.5 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-dskA_traR PF01258.17 KIK48324.1 - 1.1 9.2 8.1 15 5.7 0.0 3.7 3 1 1 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger zinc-ribbons_6 PF07191.12 KIK48324.1 - 1.2 9.2 13.7 27 4.8 13.7 2.2 1 1 0 1 1 1 0 zinc-ribbons NOB1_Zn_bind PF08772.11 KIK48324.1 - 3.2 8.0 11.1 3.7 7.8 4.0 2.8 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like F-box PF00646.33 KIK48326.1 - 0.06 13.2 1.0 0.13 12.1 1.0 1.6 1 0 0 1 1 1 0 F-box domain Methyltransf_16 PF10294.9 KIK48327.1 - 3.2e-15 56.3 0.0 4.8e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase GidB PF02527.15 KIK48327.1 - 0.00044 19.6 0.0 0.0008 18.8 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_25 PF13649.6 KIK48327.1 - 0.011 16.4 0.0 0.025 15.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KIK48327.1 - 0.019 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 KIK48327.1 - 0.027 14.2 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KIK48327.1 - 0.12 13.2 0.0 0.32 11.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain WD40 PF00400.32 KIK48328.1 - 7.2e-23 80.5 15.3 0.0023 18.7 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KIK48328.1 - 0.059 12.3 0.1 1.7 7.6 0.0 2.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SIR2 PF02146.17 KIK48329.1 - 4.3e-28 98.4 0.0 6.5e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF4451 PF14616.6 KIK48331.1 - 0.0029 17.8 7.6 1.2 9.3 0.4 3.2 1 1 2 3 3 3 3 Domain of unknown function (DUF4451) zf_C2HC_14 PF18574.1 KIK48331.1 - 2.3 8.1 6.1 28 4.6 0.3 3.4 3 0 0 3 3 3 0 C2HC Zing finger domain DUF4685 PF15737.5 KIK48331.1 - 6.7 7.2 9.3 2.2 8.7 3.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4685) Glyco_hydro_16 PF00722.21 KIK48335.1 - 6.5e-06 25.7 0.1 3e-05 23.6 0.0 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 KIK48338.1 - 6.2e-06 25.8 0.0 1.7e-05 24.4 0.0 1.7 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 KIK48339.1 - 3.4e-07 29.9 0.3 7e-07 28.9 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 KIK48340.1 - 9.8e-05 21.9 0.1 0.00025 20.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 PGM_PMM_I PF02878.16 KIK48341.1 - 5.9e-33 113.5 0.2 1.2e-32 112.5 0.2 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KIK48341.1 - 2e-26 92.4 0.0 5.6e-26 91.0 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KIK48341.1 - 2.5e-13 50.5 0.0 1.2e-12 48.4 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KIK48341.1 - 1.6e-06 28.2 0.0 4.1e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain NTF2 PF02136.20 KIK48342.1 - 2.3e-14 54.0 0.0 1.4e-12 48.2 0.0 2.2 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 KIK48342.1 - 6.8e-08 32.6 0.0 8.1e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 HA2 PF04408.23 KIK48343.1 - 8.3e-25 87.2 0.1 8.3e-25 87.2 0.1 2.5 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIK48343.1 - 7.2e-24 84.0 0.0 1.5e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIK48343.1 - 1.9e-13 50.8 0.0 5.6e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KIK48343.1 - 1e-08 35.4 0.0 2.4e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 KIK48343.1 - 2.9e-05 23.9 0.1 6e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KIK48343.1 - 0.00026 20.1 0.0 0.00067 18.8 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 KIK48343.1 - 0.0014 18.9 0.0 0.0043 17.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KIK48343.1 - 0.0023 17.3 0.0 0.0046 16.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KIK48343.1 - 0.0025 17.5 0.0 0.0056 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIK48343.1 - 0.0046 17.3 0.0 0.0087 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KIK48343.1 - 0.024 15.2 1.7 2.2 8.8 0.1 3.6 2 2 0 2 2 2 0 ABC transporter PhoH PF02562.16 KIK48343.1 - 0.13 11.7 0.0 0.32 10.4 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Pericardin_rpt PF07054.11 KIK48345.1 - 0.028 14.6 0.0 0.038 14.1 0.0 1.2 1 0 0 1 1 1 0 Pericardin like repeat HA2 PF04408.23 KIK48346.1 - 5.1e-20 71.8 0.0 1.5e-19 70.2 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIK48346.1 - 2.1e-15 56.8 0.0 5.4e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIK48346.1 - 6.4e-12 45.8 0.1 1.7e-11 44.4 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIK48346.1 - 9.7e-09 35.2 0.1 1.8e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KIK48346.1 - 0.00082 19.7 0.1 0.003 17.8 0.1 2.0 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KIK48346.1 - 0.07 13.0 0.1 0.36 10.7 0.1 2.1 1 1 0 1 1 1 0 NACHT domain ATPase PF06745.13 KIK48346.1 - 0.084 12.2 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 KIK48346.1 - 0.094 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein HisKA PF00512.25 KIK48346.1 - 0.12 12.4 0.1 0.73 9.9 0.0 2.3 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain ABC_tran PF00005.27 KIK48346.1 - 0.13 12.7 0.0 0.41 11.2 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 KIK48346.1 - 0.16 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Exo5 PF09810.9 KIK48350.1 - 9.1e-67 226.1 0.9 1.8e-56 192.2 0.1 3.0 2 1 0 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 KIK48350.1 - 0.0016 18.4 0.0 0.81 9.5 0.0 2.7 3 0 0 3 3 3 2 PD-(D/E)XK nuclease superfamily UIM PF02809.20 KIK48350.1 - 0.17 11.8 1.1 0.49 10.4 1.1 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Ctr PF04145.15 KIK48352.1 - 2.4 8.8 17.8 0.11 13.1 3.6 2.9 1 1 2 3 3 3 0 Ctr copper transporter family Pkinase PF00069.25 KIK48353.1 - 3.6e-38 131.4 0.0 5.4e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK48353.1 - 1.7e-28 99.6 0.0 2.4e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK48353.1 - 0.00017 20.7 0.0 0.00024 20.2 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIK48353.1 - 0.00052 20.0 0.1 0.037 14.0 0.0 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIK48353.1 - 0.059 12.7 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Kinase-like NAD_binding_2 PF03446.15 KIK48354.1 - 3e-20 73.0 0.0 4.9e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KIK48354.1 - 2.7e-07 30.7 0.1 6.8e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.6 KIK48354.1 - 4.8e-05 23.6 0.1 0.00011 22.5 0.1 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KIK48354.1 - 0.00039 20.9 0.0 0.0011 19.5 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 KIK48354.1 - 0.00098 19.6 0.1 1 9.8 0.0 2.6 2 1 1 3 3 3 2 Semialdehyde dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KIK48354.1 - 0.0018 17.7 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KIK48354.1 - 0.03 15.2 0.0 0.05 14.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold OCD_Mu_crystall PF02423.15 KIK48354.1 - 0.034 13.1 0.0 0.07 12.1 0.0 1.5 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family DUF840 PF05801.11 KIK48354.1 - 0.035 14.2 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Lagovirus protein of unknown function (DUF840) NAD_binding_2 PF03446.15 KIK48357.1 - 8e-21 74.8 0.0 1.1e-20 74.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KIK48357.1 - 1.7e-07 31.4 0.0 5.1e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.6 KIK48357.1 - 2e-06 28.0 0.1 4.1e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KIK48357.1 - 3.1e-06 27.7 0.1 2.2e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 KIK48357.1 - 0.0072 16.8 0.1 4.6 7.7 0.0 2.4 1 1 1 2 2 2 2 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KIK48357.1 - 0.01 16.7 0.0 0.017 15.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GAD-like PF08887.11 KIK48358.1 - 0.14 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 GAD-like domain HEAT_EZ PF13513.6 KIK48359.1 - 0.0011 19.4 2.8 17 6.0 0.0 5.2 6 0 0 6 6 6 1 HEAT-like repeat HEAT_2 PF13646.6 KIK48359.1 - 0.0076 16.6 0.2 6.5 7.2 0.0 3.3 3 0 0 3 3 3 2 HEAT repeats RTP1_C1 PF10363.9 KIK48359.1 - 0.008 16.4 0.0 2.6 8.3 0.0 2.6 2 0 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KIK48359.1 - 0.017 15.1 0.0 0.017 15.1 0.0 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KIK48359.1 - 0.034 14.2 0.0 0.2 11.7 0.0 2.3 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 KIK48359.1 - 0.1 12.9 0.0 0.44 10.8 0.0 2.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT PF02985.22 KIK48359.1 - 0.21 11.9 8.9 5 7.6 0.1 5.4 6 0 0 6 6 6 0 HEAT repeat BatD PF13584.6 KIK48360.1 - 0.041 12.7 0.0 0.065 12.0 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance SCF PF02404.15 KIK48360.1 - 0.16 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Stem cell factor Sin3a_C PF16879.5 KIK48361.1 - 5.3e-77 259.3 0.7 3.9e-76 256.5 0.0 2.7 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 KIK48361.1 - 2.1e-40 136.6 15.0 9.3e-19 67.3 0.0 4.1 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KIK48361.1 - 9.7e-38 128.2 0.1 2.4e-37 126.9 0.1 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor XendoU PF09412.10 KIK48361.1 - 0.079 12.2 1.4 1.2 8.3 0.1 2.4 2 0 0 2 2 2 0 Endoribonuclease XendoU GBP_C PF02841.14 KIK48361.1 - 1.5 8.2 5.7 0.13 11.7 0.9 1.6 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain SIX1_SD PF16878.5 KIK48361.1 - 9.2 6.8 6.8 2 9.0 0.2 3.1 4 0 0 4 4 4 0 Transcriptional regulator, SIX1, N-terminal SD domain SH3_1 PF00018.28 KIK48363.1 - 2.2e-11 43.2 0.1 4e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KIK48363.1 - 6.3e-09 35.4 0.0 1.3e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KIK48363.1 - 3.5e-07 30.0 0.0 6.3e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KIK48363.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain KLRAQ PF10205.9 KIK48365.1 - 0.0072 16.6 1.1 0.098 12.9 1.9 2.0 2 0 0 2 2 2 1 Predicted coiled-coil domain-containing protein F-box-like PF12937.7 KIK48365.1 - 0.01 15.7 3.2 0.024 14.5 1.1 2.6 2 1 0 2 2 2 0 F-box-like Helo_like_N PF17111.5 KIK48365.1 - 0.041 13.2 0.2 0.085 12.2 0.2 1.4 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins bZIP_1 PF00170.21 KIK48365.1 - 0.1 12.7 0.8 0.24 11.5 0.8 1.6 1 0 0 1 1 1 0 bZIP transcription factor LRR_4 PF12799.7 KIK48365.1 - 0.19 12.2 0.8 2.2 8.8 0.2 3.1 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) ZapB PF06005.12 KIK48365.1 - 0.2 12.1 1.3 0.41 11.1 1.3 1.5 1 0 0 1 1 1 0 Cell division protein ZapB F-box-like PF12937.7 KIK48367.1 - 0.0019 18.0 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK48367.1 - 0.1 12.5 1.1 2.4 8.1 0.2 2.2 2 0 0 2 2 2 0 F-box domain Wbp11 PF09429.10 KIK48369.1 - 2e-23 82.5 8.8 4.2e-23 81.5 8.8 1.5 1 0 0 1 1 1 1 WW domain binding protein 11 NpwBP PF12622.7 KIK48369.1 - 8.8e-13 48.8 16.3 8.8e-13 48.8 16.3 5.0 3 2 0 3 3 3 1 mRNA biogenesis factor zf-C3HC4 PF00097.25 KIK48370.1 - 9.5e-10 38.2 4.6 3.1e-09 36.6 4.9 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK48370.1 - 3.6e-08 33.3 7.8 3.8e-07 30.0 4.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIK48370.1 - 2.9e-07 30.2 7.9 5.5e-06 26.1 8.7 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK48370.1 - 4.3e-07 30.2 9.3 9.4e-07 29.1 9.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIK48370.1 - 2.7e-06 27.2 5.6 4.7e-06 26.4 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK48370.1 - 2.6e-05 24.3 9.8 4.8e-05 23.4 9.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KIK48370.1 - 0.0002 21.2 6.2 0.00044 20.2 6.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 KIK48370.1 - 0.0026 17.5 4.0 0.0058 16.4 4.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KIK48370.1 - 0.016 15.1 5.8 0.045 13.6 6.0 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.20 KIK48370.1 - 0.017 14.8 8.1 0.054 13.3 8.3 1.8 2 0 0 2 2 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.7 KIK48370.1 - 0.029 14.7 5.3 0.061 13.6 5.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KIK48370.1 - 0.39 10.8 3.2 0.72 9.9 3.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 KIK48370.1 - 2.5 8.3 5.5 7.2 6.8 5.5 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 KIK48370.1 - 7.1 6.5 10.2 2.3 8.0 4.2 2.8 3 0 0 3 3 3 0 RING-like zinc finger RSN1_7TM PF02714.15 KIK48373.1 - 7.5e-17 61.5 18.9 1.3e-16 60.7 18.9 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_ext PF12621.8 KIK48373.1 - 0.00061 19.9 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RSN1_TM PF13967.6 KIK48373.1 - 0.001 18.8 0.2 0.001 18.8 0.2 2.8 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport NS3_envE PF02723.14 KIK48373.1 - 1.1 9.4 3.8 1.4 9.1 0.5 2.7 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E NDK PF00334.19 KIK48374.1 - 0.13 12.2 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Nucleoside diphosphate kinase Sec1 PF00995.23 KIK48375.1 - 7.1e-123 411.8 0.0 8.6e-123 411.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Bax1-I PF01027.20 KIK48376.1 - 2.2e-37 128.9 8.9 2.2e-37 128.9 8.9 1.6 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 WD40 PF00400.32 KIK48377.1 - 3.7e-33 113.0 17.3 1.8e-07 31.7 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK48377.1 - 6.5e-12 45.6 7.1 0.011 16.0 0.1 5.8 3 1 5 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK48377.1 - 2.8e-05 23.3 0.1 1.5 7.7 0.0 3.4 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK48377.1 - 0.00014 21.8 0.3 0.12 12.3 0.0 2.8 2 2 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 KIK48377.1 - 0.0008 19.3 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 LisH Nbas_N PF15492.6 KIK48377.1 - 0.001 18.5 0.4 0.39 10.0 0.1 3.2 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KIK48377.1 - 0.0012 18.7 0.0 1.3 9.1 0.0 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK48377.1 - 0.069 11.8 0.0 0.7 8.5 0.0 2.3 3 0 0 3 3 3 0 Nucleoporin Nup120/160 WD40 PF00400.32 KIK48378.1 - 1.4e-16 60.6 16.9 0.0047 17.7 0.0 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat PDGF_N PF04692.13 KIK48378.1 - 0.055 14.2 0.1 0.13 13.1 0.1 1.5 1 0 0 1 1 1 0 Platelet-derived growth factor, N terminal region PBP1_TM PF14812.6 KIK48378.1 - 8.1 6.9 8.0 14 6.1 0.6 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RicinB_lectin_2 PF14200.6 KIK48380.1 - 0.016 15.9 0.0 0.095 13.4 0.0 2.1 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like Arginase PF00491.21 KIK48381.1 - 3.5e-83 279.3 0.0 4.4e-83 279.0 0.0 1.1 1 0 0 1 1 1 1 Arginase family Arginase PF00491.21 KIK48382.1 - 1.5e-84 283.8 0.1 1.9e-84 283.5 0.1 1.0 1 0 0 1 1 1 1 Arginase family SUR7 PF06687.12 KIK48383.1 - 5.9e-18 65.3 18.7 8.2e-18 64.8 18.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family tRNA-synt_2c PF01411.19 KIK48384.1 - 1e-211 704.3 0.0 1.3e-211 704.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KIK48384.1 - 6.9e-18 64.5 0.2 2.3e-17 62.8 0.2 2.0 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KIK48384.1 - 1.6e-15 57.7 5.9 3.5e-15 56.6 5.9 1.6 1 0 0 1 1 1 1 DHHA1 domain GTP_EFTU PF00009.27 KIK48385.1 - 9.7e-57 191.7 0.0 2e-55 187.4 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KIK48385.1 - 7.4e-32 109.7 0.0 1.8e-31 108.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KIK48385.1 - 2.6e-23 81.9 0.0 5.8e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KIK48385.1 - 5.9e-13 48.7 0.0 1.6e-12 47.3 0.0 1.7 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KIK48385.1 - 7.2e-12 45.5 0.0 2.1e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIK48385.1 - 2.4e-05 24.4 0.1 4.7e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase APH PF01636.23 KIK48386.1 - 1.9e-11 44.3 0.0 3.7e-11 43.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIK48386.1 - 0.0002 21.0 0.0 0.0004 20.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KIK48386.1 - 0.0003 20.2 0.0 0.0006 19.2 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 KIK48386.1 - 0.00045 19.2 0.0 0.00059 18.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 KIK48386.1 - 0.00054 19.3 0.0 0.91 8.7 0.0 2.4 2 1 0 2 2 2 2 Fructosamine kinase HIT PF01230.23 KIK48388.1 - 1.7e-24 86.4 0.0 2.2e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KIK48388.1 - 8.2e-08 32.7 0.0 1.1e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding NIF PF03031.18 KIK48389.1 - 3.8e-23 82.0 0.0 2.6e-20 72.8 0.0 2.2 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 KIK48389.1 - 1.9e-08 34.1 0.3 2.2e-07 30.7 0.4 2.3 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 KIK48389.1 - 2.9e-05 24.4 0.0 7.1e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Malate_synthase PF01274.22 KIK48391.1 - 4.3e-201 668.7 0.0 4.9e-201 668.6 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HLH PF00010.26 KIK48392.1 - 1.3e-05 25.1 0.0 2.4e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Zn_clus PF00172.18 KIK48393.1 - 8.3e-08 32.2 5.4 1.2e-07 31.7 5.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Albumin_I_a PF16720.5 KIK48393.1 - 0.023 14.6 0.2 0.041 13.8 0.2 1.3 1 0 0 1 1 1 0 Albumin I chain a PI-PLC-C1 PF16670.5 KIK48394.1 - 0.046 12.8 0.1 2.5 7.1 0.0 2.9 1 1 2 3 3 3 0 Phosphoinositide phospholipase C, Ca2+-dependent Sigma54_AID PF00309.20 KIK48394.1 - 0.11 12.4 0.6 0.2 11.5 0.6 1.3 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) PI-PLC-X PF00388.19 KIK48394.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Utp11 PF03998.13 KIK48395.1 - 3.1e-71 240.2 25.7 4.2e-71 239.8 25.7 1.2 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 KIK48395.1 - 0.16 11.3 0.2 0.16 11.3 0.2 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Rrn6 PF10214.9 KIK48396.1 - 2.1 6.8 7.7 0.65 8.4 0.8 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor VHS PF00790.19 KIK48397.1 - 1.2e-22 80.3 0.0 2.5e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KIK48397.1 - 3.8e-08 33.5 0.0 5.9e-06 26.5 0.2 2.7 2 0 0 2 2 2 1 GAT domain Cnd1_N PF12922.7 KIK48397.1 - 0.39 10.6 2.9 1 9.2 2.9 1.7 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term MAS20 PF02064.15 KIK48397.1 - 3 8.0 10.7 1 9.5 7.2 2.0 2 0 0 2 2 2 0 MAS20 protein import receptor Peptidase_S49_N PF08496.10 KIK48397.1 - 3 7.9 7.8 0.49 10.4 3.6 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4337 PF14235.6 KIK48397.1 - 4.6 7.3 10.6 2.1 8.4 5.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) MscS_TM PF12794.7 KIK48397.1 - 5.1 5.8 5.0 8.3 5.2 5.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Tho2 PF11262.8 KIK48397.1 - 7.1 5.7 9.3 6.6 5.8 2.9 2.6 3 1 0 3 3 3 0 Transcription factor/nuclear export subunit protein 2 DUF3105 PF11303.8 KIK48398.1 - 0.046 13.9 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) EF-hand_6 PF13405.6 KIK48399.1 - 1.3e-12 46.5 1.5 3.6e-06 26.5 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KIK48399.1 - 3.5e-11 43.4 1.5 3.3e-10 40.3 0.3 2.7 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KIK48399.1 - 2.7e-07 29.7 4.9 0.0033 16.9 0.1 3.7 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 KIK48399.1 - 0.0072 15.8 1.0 0.054 13.0 0.3 2.5 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 KIK48399.1 - 0.04 14.3 0.1 6.5 7.2 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain BNR_6 PF15899.5 KIK48399.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 BNR-Asp box repeat zf-C2H2 PF00096.26 KIK48401.1 - 4.9e-09 36.2 17.8 6.7e-05 23.1 2.0 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIK48401.1 - 9.7e-05 22.6 3.9 9.7e-05 22.6 3.9 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KIK48401.1 - 0.0011 19.1 0.7 0.0011 19.1 0.7 3.3 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIK48401.1 - 0.0021 18.4 0.7 0.0021 18.4 0.7 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KIK48401.1 - 0.0026 18.4 1.7 0.0026 18.4 1.7 3.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KIK48401.1 - 0.027 14.5 3.3 0.079 13.0 3.3 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KIK48401.1 - 0.28 11.1 1.8 0.69 9.9 1.8 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type FOXP-CC PF16159.5 KIK48401.1 - 1.5 9.5 15.3 1.1 10.0 0.3 3.2 1 1 1 2 2 2 0 FOXP coiled-coil domain Zap1_zf2 PF18217.1 KIK48401.1 - 9.4 6.3 14.4 6.2 6.9 3.8 2.4 2 0 0 2 2 2 0 Zap1 zinc finger 2 DUF3591 PF12157.8 KIK48402.1 - 1.4e-188 627.0 1.2 2.2e-188 626.4 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 KIK48402.1 - 0.00015 21.6 2.8 0.00033 20.4 2.8 1.6 1 0 0 1 1 1 1 Zinc knuckle TFIIF_beta PF02270.15 KIK48402.1 - 0.0013 18.8 0.1 0.0031 17.6 0.1 1.6 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain zf-CCHC PF00098.23 KIK48402.1 - 0.83 9.8 3.3 1.5 9.1 3.3 1.3 1 0 0 1 1 1 0 Zinc knuckle PA28_beta PF02252.18 KIK48403.1 - 3.8e-53 179.1 1.7 4.3e-53 178.9 1.0 1.4 2 0 0 2 2 2 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 KIK48403.1 - 0.021 14.8 0.4 0.059 13.4 0.1 1.9 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit WD40 PF00400.32 KIK48404.1 - 1.9e-15 57.0 11.4 1.3e-05 25.8 0.2 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KIK48404.1 - 2.4e-15 56.5 0.2 1.5e-14 54.0 0.0 2.3 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KIK48404.1 - 0.00024 21.3 0.2 0.16 12.2 0.0 3.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain MAPEG PF01124.18 KIK48405.1 - 1.2e-21 77.0 0.3 1.4e-21 76.7 0.3 1.0 1 0 0 1 1 1 1 MAPEG family DUF588 PF04535.12 KIK48405.1 - 0.047 13.5 2.9 0.062 13.1 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF588) MAPEG PF01124.18 KIK48406.1 - 4.1e-06 26.7 0.0 9.4e-06 25.6 0.0 1.5 1 1 1 2 2 2 1 MAPEG family RRM_1 PF00076.22 KIK48408.1 - 8.1e-05 22.4 0.0 0.002 17.9 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNARE PF05739.19 KIK48409.1 - 4.7e-12 45.7 0.0 1.2e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 KIK48409.1 - 2.1e-06 26.8 0.3 2.1e-06 26.8 0.3 2.6 3 0 0 3 3 3 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 KIK48409.1 - 2.8e-05 23.9 14.4 9.6e-05 22.1 0.3 2.6 2 1 1 3 3 3 2 Syntaxin Syntaxin-18_N PF10496.9 KIK48409.1 - 0.00038 20.6 0.2 0.00038 20.6 0.2 2.9 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus M_domain PF12938.7 KIK48409.1 - 0.0094 15.8 4.1 0.0094 15.8 4.1 2.5 2 2 0 2 2 2 1 M domain of GW182 BLOC1_2 PF10046.9 KIK48409.1 - 0.01 16.2 3.7 0.14 12.5 0.6 3.0 2 1 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.16 KIK48409.1 - 0.032 14.7 6.1 0.073 13.6 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 KIK48409.1 - 0.073 13.7 7.3 0.32 11.6 0.5 3.1 3 0 0 3 3 3 0 SlyX NPV_P10 PF05531.12 KIK48409.1 - 0.2 12.1 8.4 0.22 12.0 1.6 3.0 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Osmo_CC PF08946.10 KIK48409.1 - 0.72 10.1 3.9 3.5 8.0 0.2 3.5 4 0 0 4 4 4 0 Osmosensory transporter coiled coil UPF0242 PF06785.11 KIK48409.1 - 0.97 9.5 11.2 2 8.5 0.1 2.9 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF5638 PF18688.1 KIK48409.1 - 1.6 9.1 7.0 0.19 12.1 2.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5638) Allexi_40kDa PF05549.11 KIK48409.1 - 4 6.9 8.1 3.1 7.2 0.1 2.4 2 1 0 2 2 2 0 Allexivirus 40kDa protein DUF1664 PF07889.12 KIK48409.1 - 4.5 7.3 10.1 2.2 8.3 0.9 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) NAD_Gly3P_dh_C PF07479.14 KIK48410.1 - 4.5e-48 163.2 0.0 7e-48 162.5 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KIK48410.1 - 4.4e-35 121.0 0.0 1.7e-34 119.1 0.0 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 KIK48410.1 - 9e-07 29.4 0.0 2.7e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KIK48410.1 - 3.2e-06 26.9 0.0 6.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 KIK48410.1 - 0.0051 17.0 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.27 KIK48410.1 - 0.0094 16.5 0.0 2.6 8.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase PX PF00787.24 KIK48410.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 PX domain Pyr_redox_2 PF07992.14 KIK48410.1 - 0.13 11.5 0.0 0.39 9.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KIK48410.1 - 0.18 11.9 0.0 0.54 10.3 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ank_2 PF12796.7 KIK48411.1 - 3.5e-08 33.9 0.0 6.7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-CCCH_4 PF18044.1 KIK48411.1 - 3.7e-08 33.0 12.6 0.0002 21.1 2.9 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KIK48411.1 - 2.6e-06 27.7 15.5 4.1e-06 27.0 4.5 2.5 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 KIK48411.1 - 1.2e-05 25.2 16.6 0.00016 21.6 2.4 2.7 3 0 0 3 3 3 2 Zinc finger domain Ank_3 PF13606.6 KIK48411.1 - 3.1e-05 24.0 0.0 0.00032 20.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat zf-CCCH PF00642.24 KIK48411.1 - 3.2e-05 23.7 11.6 0.011 15.6 3.4 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank_4 PF13637.6 KIK48411.1 - 4.4e-05 23.9 0.0 8.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Torus PF16131.5 KIK48411.1 - 4.5e-05 24.1 2.1 0.00029 21.5 0.2 2.4 2 0 0 2 2 2 1 Torus domain Ank_5 PF13857.6 KIK48411.1 - 5.2e-05 23.4 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Phostensin PF13914.6 KIK48411.1 - 0.0011 19.6 0.3 0.0011 19.6 0.3 1.9 2 0 0 2 2 2 1 Phostensin PP1-binding and SH3-binding region Ank PF00023.30 KIK48411.1 - 0.0011 19.3 0.0 0.0025 18.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat zf-CCCH_3 PF15663.5 KIK48411.1 - 1.3 9.3 3.0 4.3 7.6 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger containing family GARS_A PF01071.19 KIK48412.1 - 4.2e-79 264.9 0.0 6.1e-79 264.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 KIK48412.1 - 1.3e-34 119.6 0.0 3.7e-34 118.1 0.0 1.7 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 KIK48412.1 - 9.7e-32 109.6 0.0 5.9e-31 107.1 0.0 2.4 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 KIK48412.1 - 4.6e-27 94.1 0.1 9.7e-27 93.1 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KIK48412.1 - 8.8e-16 58.3 3.3 2.6e-14 53.6 1.2 2.8 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 KIK48412.1 - 7.1e-07 28.9 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_ST PF14397.6 KIK48412.1 - 0.066 12.4 0.0 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 KIK48412.1 - 0.068 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KIK48412.1 - 0.078 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.6 KIK48412.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain BCL_N PF04714.13 KIK48416.1 - 0.0021 18.1 0.6 0.0038 17.3 0.6 1.4 1 0 0 1 1 1 1 BCL7, N-terminal conserver region Med7 PF05983.11 KIK48418.1 - 4.5e-49 167.1 0.1 5.5e-49 166.8 0.1 1.1 1 0 0 1 1 1 1 MED7 protein Mating_C PF12737.7 KIK48418.1 - 0.013 14.8 0.1 0.018 14.3 0.1 1.2 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 MRP-S25 PF13741.6 KIK48419.1 - 1.6e-48 165.2 5.6 1.3e-38 132.9 0.3 2.2 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KIK48419.1 - 2e-05 24.9 1.6 6.9e-05 23.1 1.6 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 PCI PF01399.27 KIK48420.1 - 1.5e-15 57.6 0.0 1.1e-14 54.8 0.0 2.5 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 KIK48420.1 - 2.4e-05 24.3 1.2 2.4e-05 24.3 1.2 1.8 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain F-box-like PF12937.7 KIK48421.1 - 0.061 13.2 0.1 0.4 10.6 0.0 2.5 2 0 0 2 2 2 0 F-box-like Drc1-Sld2 PF11719.8 KIK48422.1 - 3.8e-14 53.1 2.0 3.8e-14 53.1 2.0 3.4 2 2 0 3 3 3 1 DNA replication and checkpoint protein TFIIE-A_C PF11521.8 KIK48422.1 - 0.058 13.7 3.8 0.088 13.1 2.4 2.1 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Pal1 PF08316.11 KIK48423.1 - 0.0008 20.2 0.1 0.002 18.9 0.1 1.7 1 0 0 1 1 1 1 Pal1 cell morphology protein p450 PF00067.22 KIK48424.1 - 2e-52 178.5 0.1 2.6e-52 178.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 SF3A2 PF16835.5 KIK48425.1 - 8.9e-11 42.0 0.1 1.2e-10 41.6 0.1 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) RdRP PF05183.12 KIK48426.1 - 3.6e-111 372.6 0.0 4.9e-111 372.2 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase MMR_HSR1 PF01926.23 KIK48427.1 - 4.9e-16 58.8 0.1 7.6e-15 55.0 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIK48427.1 - 3e-06 27.2 0.0 0.0055 16.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KIK48427.1 - 1.8e-05 24.3 0.1 0.00011 21.8 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 KIK48427.1 - 0.0037 16.6 0.0 0.0081 15.5 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIK48427.1 - 0.012 15.6 0.0 0.045 13.8 0.0 2.0 1 0 0 1 1 1 0 Dynamin family Pkinase PF00069.25 KIK48428.1 - 1.8e-40 138.9 0.0 2.5e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK48428.1 - 2.9e-26 92.3 0.0 3.9e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KIK48428.1 - 0.0036 17.6 0.2 0.01 16.2 0.1 1.8 1 1 1 2 2 2 1 FHA domain zf-C2H2 PF00096.26 KIK48430.1 - 0.2 12.2 0.9 0.34 11.4 0.6 1.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type PGAP1 PF07819.13 KIK48431.1 - 1.5e-05 24.8 0.1 3e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 KIK48431.1 - 2.1e-05 24.5 0.0 3.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KIK48431.1 - 0.00099 19.8 2.1 0.0019 18.9 0.2 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK48431.1 - 0.002 17.9 0.1 0.01 15.5 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 KIK48431.1 - 0.021 14.3 0.1 0.056 12.9 0.0 1.6 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KIK48431.1 - 0.031 13.5 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF915 PF06028.11 KIK48431.1 - 0.055 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KIK48432.1 - 2e-41 142.3 0.0 2.3e-41 142.1 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 KIK48432.1 - 0.018 13.9 0.0 0.08 11.8 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase enzyme Esterase_phd PF10503.9 KIK48432.1 - 0.025 14.1 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KIK48432.1 - 0.03 13.6 0.1 0.069 12.4 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIK48432.1 - 0.11 13.1 0.5 0.31 11.6 0.5 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family Kelch_3 PF13415.6 KIK48433.1 - 1e-33 115.0 12.8 1.8e-08 34.5 0.1 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KIK48433.1 - 3.2e-30 103.6 4.1 2.8e-05 24.0 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 KIK48433.1 - 3.8e-30 103.2 6.3 3.7e-09 36.0 0.5 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KIK48433.1 - 4.2e-30 103.5 16.4 3.6e-07 30.1 1.1 6.5 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KIK48433.1 - 8.6e-28 95.7 8.8 5.8e-09 35.9 0.5 6.5 3 2 3 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KIK48433.1 - 1.2e-21 75.7 5.1 5e-05 23.1 0.1 6.6 6 0 0 6 6 6 5 Kelch motif Pepsin-I3 PF06394.13 KIK48433.1 - 0.064 13.5 0.5 0.39 11.0 0.5 2.4 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain S1 PF00575.23 KIK48434.1 - 5.4e-25 87.5 0.8 1.1e-05 25.7 0.0 6.6 6 1 0 6 6 6 4 S1 RNA binding domain TPR_19 PF14559.6 KIK48434.1 - 1.4e-05 25.5 0.0 0.32 11.6 0.0 3.5 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIK48434.1 - 3.5e-05 24.3 1.3 9.7 7.3 0.0 5.1 2 2 4 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIK48434.1 - 0.0013 19.3 0.0 15 6.3 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIK48434.1 - 0.0066 16.7 4.8 0.48 10.7 0.3 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KIK48434.1 - 0.0085 15.3 10.2 0.66 9.0 1.6 3.4 2 1 1 3 3 3 2 NRDE-2, necessary for RNA interference Suf PF05843.14 KIK48434.1 - 0.066 13.2 0.1 0.066 13.2 0.1 4.0 2 1 3 5 5 5 0 Suppressor of forked protein (Suf) IIGP PF05049.13 KIK48434.1 - 0.078 12.0 0.1 9.5 5.2 0.1 2.4 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) DUF2442 PF10387.9 KIK48434.1 - 0.088 13.1 0.0 0.33 11.3 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) TPR_21 PF09976.9 KIK48434.1 - 0.17 11.6 4.2 0.068 12.9 0.7 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain SF3A2 PF16835.5 KIK48435.1 - 4.4e-37 126.3 0.3 6.6e-37 125.8 0.3 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KIK48435.1 - 1.1e-06 28.8 1.1 2e-06 28.0 0.7 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.11 KIK48435.1 - 0.0086 15.6 0.9 0.016 14.7 0.9 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like CactinC_cactus PF09732.9 KIK48435.1 - 0.023 14.7 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein TraE PF05309.11 KIK48436.1 - 0.5 9.7 4.8 0.49 9.7 0.7 2.3 1 1 1 2 2 2 0 TraE protein FA_desaturase PF00487.24 KIK48436.1 - 6.1 6.6 9.6 0.097 12.5 0.9 2.1 1 1 2 3 3 3 0 Fatty acid desaturase Sec8_exocyst PF04048.14 KIK48438.1 - 1e-32 113.0 0.6 2e-32 112.0 0.6 1.5 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KIK48438.1 - 0.00014 21.2 0.3 0.00031 20.1 0.3 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KIK48438.1 - 0.00021 21.1 0.0 0.00059 19.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) IZUMO PF15005.6 KIK48438.1 - 0.14 12.7 1.7 1.5 9.4 0.9 2.9 3 0 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated LIDHydrolase PF10230.9 KIK48439.1 - 6.9e-48 163.5 0.0 8.2e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KIK48439.1 - 0.00012 22.8 1.6 0.00016 22.3 1.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIK48439.1 - 0.041 13.2 0.0 0.064 12.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 SNF2_N PF00176.23 KIK48440.1 - 1.9e-54 184.7 0.1 2.9e-54 184.1 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK48440.1 - 4e-20 72.2 0.0 9.2e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KIK48440.1 - 9e-18 64.4 0.2 1.9e-17 63.4 0.2 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 zf-PHD-like PF15446.6 KIK48440.1 - 7.4e-10 38.7 5.0 3.2e-05 23.6 0.1 3.1 3 0 0 3 3 3 2 PHD/FYVE-zinc-finger like domain Chromo PF00385.24 KIK48440.1 - 0.00016 21.5 3.6 0.1 12.6 0.1 3.5 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 KIK48440.1 - 0.00043 20.3 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KIK48440.1 - 0.0016 17.7 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Fucokinase PF07959.12 KIK48440.1 - 0.013 14.5 0.3 0.14 11.1 0.0 2.2 2 0 0 2 2 2 0 L-fucokinase TraV PF09676.10 KIK48440.1 - 0.13 13.2 0.1 0.13 13.2 0.1 4.3 5 0 0 5 5 4 0 Type IV conjugative transfer system lipoprotein (TraV) DUF5419 PF17441.2 KIK48440.1 - 0.2 11.8 1.3 3.1 8.0 0.3 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5419) SIR4_SID PF16991.5 KIK48440.1 - 5.3 7.1 8.4 0.13 12.3 0.5 2.4 3 0 0 3 3 3 0 Sir4 SID domain Ribonucleas_3_3 PF14622.6 KIK48441.1 - 3.1e-09 37.1 0.0 5.9e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 KIK48441.1 - 9.6e-08 32.6 0.0 2.2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 KIK48441.1 - 0.00017 22.2 0.2 0.0011 19.6 0.2 2.2 1 1 0 1 1 1 1 Ribonuclease III domain SNF2_N PF00176.23 KIK48442.1 - 1.2e-70 238.0 0.0 2.4e-70 237.0 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIK48442.1 - 6.8e-14 52.2 0.0 1.6e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KIK48442.1 - 0.0034 17.3 1.9 0.0034 17.3 1.9 1.8 2 0 0 2 2 2 1 zinc-RING finger domain ResIII PF04851.15 KIK48442.1 - 0.031 14.3 0.0 0.97 9.4 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KIK48442.1 - 0.048 13.5 1.6 0.14 12.0 1.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIK48442.1 - 0.11 12.3 1.1 0.36 10.7 1.1 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK48442.1 - 0.13 12.3 1.4 0.4 10.7 1.4 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KIK48442.1 - 0.3 11.0 2.3 0.79 9.6 2.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KIK48442.1 - 0.4 11.1 2.7 3.8 7.9 0.6 2.7 2 0 0 2 2 2 0 Ring finger domain ThrE PF06738.12 KIK48443.1 - 4.9e-48 163.6 25.8 4.8e-47 160.4 12.0 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KIK48443.1 - 1.9e-09 37.8 5.0 1.9e-09 37.8 5.0 2.5 2 1 0 2 2 2 1 Threonine/Serine exporter, ThrE PetL PF05115.14 KIK48443.1 - 0.017 15.1 5.0 0.2 11.6 1.2 3.2 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) DUF4131 PF13567.6 KIK48443.1 - 0.018 14.7 1.3 0.018 14.7 1.3 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Zn_clus PF00172.18 KIK48444.1 - 3e-07 30.4 10.4 5.4e-07 29.6 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIK48444.1 - 0.00057 19.0 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain AlkA_N PF06029.11 KIK48444.1 - 0.033 14.4 0.1 0.092 13.0 0.1 1.7 1 0 0 1 1 1 0 AlkA N-terminal domain Homeodomain PF00046.29 KIK48446.1 - 6.1e-16 58.0 0.2 3.7e-15 55.5 0.1 2.0 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KIK48446.1 - 0.0015 18.4 0.1 0.07 13.0 0.2 2.9 3 1 0 3 3 3 1 Homeobox KN domain Homez PF11569.8 KIK48446.1 - 0.0061 16.0 0.0 0.12 11.9 0.0 2.8 4 0 0 4 4 4 1 Homeodomain leucine-zipper encoding, Homez HTH_3 PF01381.22 KIK48446.1 - 0.064 13.3 0.2 0.35 11.0 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix TB2_DP1_HVA22 PF03134.19 KIK48447.1 - 2.2e-22 78.8 3.7 4.2e-22 77.9 3.7 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Sec3_C PF09763.9 KIK48448.1 - 6.2e-156 520.7 2.6 8.3e-156 520.3 2.6 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KIK48448.1 - 2.7e-20 72.3 0.1 7.6e-20 70.8 0.0 1.8 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 KIK48448.1 - 0.0032 16.3 1.1 0.0061 15.4 1.1 1.4 1 0 0 1 1 1 1 Vps52 / Sac2 family Homeodomain PF00046.29 KIK48449.1 - 1.8e-08 34.1 0.1 3.2e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KIK48449.1 - 0.002 18.0 0.1 0.0042 16.9 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain CPT_N PF16484.5 KIK48449.1 - 0.11 12.5 0.0 4.5 7.3 0.0 2.7 2 0 0 2 2 2 0 Carnitine O-palmitoyltransferase N-terminus Glyco_transf_21 PF13506.6 KIK48450.1 - 5.8e-26 91.0 0.1 7.8e-21 74.3 0.0 2.3 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KIK48450.1 - 2e-14 54.1 0.0 2.4e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIK48450.1 - 5.8e-05 23.0 0.0 9.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 TatD_DNase PF01026.21 KIK48451.1 - 4.4e-49 167.2 0.0 5.5e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Corona_NS2A PF05213.12 KIK48451.1 - 0.063 12.6 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NS2A protein SSF PF00474.17 KIK48452.1 - 1.6e-21 76.7 34.5 2.8e-21 75.9 34.5 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Thiolase_N PF00108.23 KIK48453.1 - 7.9e-67 225.3 0.3 1e-66 225.0 0.3 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIK48453.1 - 9.8e-30 102.7 0.1 4e-29 100.8 0.0 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KIK48453.1 - 0.00039 20.2 0.1 0.012 15.4 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KIK48453.1 - 0.0035 16.9 0.0 0.013 15.1 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Hepar_II_III PF07940.13 KIK48454.1 - 9.4e-10 38.5 0.5 1.7e-09 37.6 0.5 1.4 1 0 0 1 1 1 1 Heparinase II/III-like protein Rick_17kDa_Anti PF05433.15 KIK48454.1 - 0.14 12.1 5.4 0.36 10.7 5.4 1.7 1 0 0 1 1 1 0 Glycine zipper 2TM domain CXCR4_N PF12109.8 KIK48454.1 - 0.35 11.1 1.5 25 5.2 0.4 2.7 2 0 0 2 2 2 0 CXCR4 Chemokine receptor N terminal SOG2 PF10428.9 KIK48455.1 - 0.059 12.6 22.9 0.078 12.2 22.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein EF_assoc_2 PF08356.12 KIK48455.1 - 0.065 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 EF hand associated PgaD PF13994.6 KIK48455.1 - 0.15 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 PgaD-like protein SPX PF03105.19 KIK48455.1 - 0.76 9.6 12.0 0.92 9.4 12.0 1.3 1 0 0 1 1 1 0 SPX domain DUF4834 PF16118.5 KIK48455.1 - 0.88 10.6 2.4 1.5 9.8 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Apt1 PF10351.9 KIK48455.1 - 0.88 8.3 6.4 1 8.1 6.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ima1_N PF09779.9 KIK48456.1 - 9e-35 120.5 1.9 1.5e-34 119.7 1.9 1.3 1 0 0 1 1 1 1 Ima1 N-terminal domain OrfB_Zn_ribbon PF07282.11 KIK48456.1 - 0.022 14.7 1.9 0.022 14.7 1.9 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain HA PF03457.14 KIK48456.1 - 0.38 11.1 1.6 0.37 11.2 0.2 1.7 2 0 0 2 2 2 0 Helicase associated domain DZR PF12773.7 KIK48456.1 - 0.49 10.5 6.8 11 6.1 0.1 2.6 2 1 0 2 2 2 0 Double zinc ribbon SNAPc_SNAP43 PF09808.9 KIK48457.1 - 0.0043 17.0 0.0 0.0056 16.6 0.0 1.1 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 SKN1 PF03935.15 KIK48459.1 - 1.5e-184 614.1 7.7 1.8e-184 613.8 7.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) UQ_con PF00179.26 KIK48460.1 - 4.4e-20 71.8 0.0 7.9e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF4537 PF15057.6 KIK48460.1 - 0.022 14.8 0.1 0.084 12.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) F-box-like PF12937.7 KIK48461.1 - 7.7e-07 28.9 0.2 2e-06 27.6 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK48461.1 - 1.4e-05 24.8 0.3 7.4e-05 22.5 0.1 2.4 2 0 0 2 2 2 1 F-box domain NAT PF04768.13 KIK48463.1 - 1.9e-32 112.3 0.3 8.5e-19 67.8 0.0 2.3 2 0 0 2 2 2 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase Mito_carr PF00153.27 KIK48466.1 - 2.6e-64 213.2 4.9 4.3e-22 77.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fasciclin PF02469.22 KIK48467.1 - 1.3e-64 216.1 0.0 3.3e-14 53.2 0.0 5.5 6 0 0 6 6 6 5 Fasciclin domain YGGT PF02325.17 KIK48467.1 - 0.16 12.4 0.3 0.41 11.1 0.3 1.7 1 0 0 1 1 1 0 YGGT family Rav1p_C PF12234.8 KIK48468.1 - 1.3e-204 681.3 0.0 1.7e-204 680.9 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal GDI PF00996.18 KIK48469.1 - 7.7e-214 710.1 0.0 8.8e-214 709.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor UPF0183 PF03676.14 KIK48473.1 - 0.16 11.3 0.4 11 5.1 0.2 2.0 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0183) Seipin PF06775.14 KIK48474.1 - 1.1e-23 84.4 0.2 1.5e-22 80.6 0.2 2.0 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) adh_short_C2 PF13561.6 KIK48475.1 - 1.4e-46 159.0 0.2 2.4e-46 158.2 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK48475.1 - 5.7e-42 143.4 0.1 8.5e-42 142.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK48475.1 - 8.5e-10 38.8 0.0 1.8e-09 37.8 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KIK48475.1 - 0.00046 19.7 0.0 0.0011 18.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KIK48475.1 - 0.095 12.0 0.0 0.29 10.4 0.0 1.8 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 KIK48475.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SH3BGR PF04908.15 KIK48476.1 - 8.9e-17 61.1 0.0 1.7e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 KIK48476.1 - 0.062 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin Aldedh PF00171.22 KIK48477.1 - 2.6e-127 425.1 0.5 3e-127 424.9 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DNA_pol_phi PF04931.13 KIK48478.1 - 3.3 5.7 7.8 4.8 5.2 7.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi LCCL PF03815.19 KIK48479.1 - 1.8e-14 53.6 0.0 3.5e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 LCCL domain DUF3368 PF11848.8 KIK48480.1 - 0.076 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) GRP PF07172.11 KIK48482.1 - 0.00045 20.8 0.3 0.00056 20.6 0.3 1.2 1 0 0 1 1 1 1 Glycine rich protein family DUF2718 PF10918.8 KIK48484.1 - 0.21 12.1 0.7 1.8 9.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2718) AA_permease PF00324.21 KIK48486.1 - 1.8e-121 406.0 43.1 2.2e-121 405.8 43.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIK48486.1 - 1.6e-32 112.9 44.6 2.1e-32 112.5 44.6 1.1 1 0 0 1 1 1 1 Amino acid permease TAL_FSA PF00923.19 KIK48487.1 - 1.9e-23 83.2 0.0 3e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase bZIP_1 PF00170.21 KIK48489.1 - 3.5e-05 23.8 11.5 0.00042 20.3 2.7 2.3 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 KIK48489.1 - 3.8e-05 23.7 13.6 6.1e-05 23.0 0.2 2.5 3 0 0 3 3 3 2 Basic region leucine zipper YabA PF06156.13 KIK48489.1 - 0.00075 20.1 0.4 0.0012 19.5 0.4 1.5 1 1 0 1 1 1 1 Initiation control protein YabA SIKE PF05769.11 KIK48489.1 - 0.0079 16.1 0.7 0.0079 16.1 0.7 1.9 1 1 1 2 2 2 1 SIKE family TSC22 PF01166.18 KIK48489.1 - 0.0088 16.3 2.2 0.066 13.5 1.5 2.2 2 0 0 2 2 2 1 TSC-22/dip/bun family CCDC85 PF10226.9 KIK48489.1 - 0.0093 15.7 0.2 0.014 15.0 0.2 1.3 1 0 0 1 1 1 1 CCDC85 family NYD-SP28_assoc PF14775.6 KIK48489.1 - 0.018 15.1 7.4 0.035 14.2 3.0 2.2 2 0 0 2 2 2 0 Sperm tail C-terminal domain AAA_32 PF13654.6 KIK48489.1 - 0.063 12.1 0.6 0.057 12.2 0.6 1.0 1 0 0 1 1 1 0 AAA domain FlaG PF03646.15 KIK48489.1 - 0.19 11.9 1.8 0.45 10.7 1.8 1.7 1 1 0 1 1 1 0 FlaG protein Shugoshin_N PF07558.11 KIK48489.1 - 0.28 11.1 7.5 0.4 10.6 4.3 2.1 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.15 KIK48489.1 - 1.3 8.8 8.6 3.8 7.3 1.6 2.2 1 1 0 2 2 2 0 Septum formation initiator TIMELESS PF04821.14 KIK48491.1 - 6.1e-81 271.7 0.3 6.1e-81 271.7 0.3 2.3 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.13 KIK48491.1 - 2e-13 50.4 0.0 2e-13 50.4 0.0 2.5 1 1 0 2 2 2 1 Timeless protein C terminal region RNA_pol_Rpb4 PF03874.16 KIK48491.1 - 0.075 13.4 4.9 2.4 8.5 0.8 3.7 3 0 0 3 3 3 0 RNA polymerase Rpb4 Polysacc_synt_4 PF04669.13 KIK48492.1 - 9.2e-21 74.3 1.2 1.4e-18 67.1 1.2 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis Longin_2 PF18639.1 KIK48492.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Yeast longin domain Myb_DNA-binding PF00249.31 KIK48493.1 - 3.5e-08 33.5 0.1 6.7e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK48493.1 - 0.018 15.3 0.1 0.045 14.0 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain DNA_pol_viral_C PF00336.18 KIK48495.1 - 0.093 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Pkinase PF00069.25 KIK48496.1 - 2.4e-62 210.7 0.0 5.4e-62 209.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK48496.1 - 1.8e-44 152.0 0.0 6.7e-44 150.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3543 PF12063.8 KIK48496.1 - 1e-37 129.9 1.1 2.3e-37 128.7 1.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_fungal PF17667.1 KIK48496.1 - 0.0067 15.3 0.0 0.028 13.2 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KIK48496.1 - 0.021 14.8 0.1 0.021 14.8 0.1 3.7 3 1 0 4 4 4 0 Phosphotransferase enzyme family zf-CCHC PF00098.23 KIK48497.1 - 1.2 9.4 8.4 0.082 13.0 2.7 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 KIK48497.1 - 7.1 6.4 10.3 0.84 9.4 2.7 2.3 2 0 0 2 2 2 0 Zinc knuckle Phage_integrase PF00589.22 KIK48498.1 - 0.045 13.6 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family Nab1 PF04902.12 KIK48500.1 - 0.021 15.2 0.0 0.031 14.7 0.0 1.2 1 0 0 1 1 1 0 Conserved region in Nab1 F-box-like PF12937.7 KIK48501.1 - 1.9e-06 27.6 2.9 1.6e-05 24.7 2.7 2.8 3 1 0 3 3 3 1 F-box-like RNA_Me_trans PF04252.13 KIK48502.1 - 2.7e-79 265.4 0.0 3e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase FAD_binding_3 PF01494.19 KIK48503.1 - 4.2e-18 65.7 0.0 1.6e-09 37.5 0.0 2.6 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KIK48503.1 - 0.0019 17.8 0.1 0.0044 16.7 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK48503.1 - 0.0069 16.6 0.1 0.022 15.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIK48503.1 - 0.095 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KIK48503.1 - 0.16 11.2 0.0 0.42 9.8 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aminotran_1_2 PF00155.21 KIK48504.1 - 1.5e-36 126.4 0.0 1.8e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIK48504.1 - 0.0049 15.5 0.0 0.0082 14.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Hydrolase_6 PF13344.6 KIK48505.1 - 1.1e-30 105.7 0.0 2.2e-30 104.8 0.0 1.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIK48505.1 - 1.6e-19 69.8 0.0 3.2e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KIK48505.1 - 1.2e-11 45.4 0.0 5.1e-11 43.3 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KIK48505.1 - 2.5e-08 34.2 0.0 0.00051 20.2 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KIK48505.1 - 0.0069 16.0 0.0 0.025 14.2 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase Acid_phosphat_B PF03767.14 KIK48505.1 - 0.2 11.2 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) PIG-F PF06699.11 KIK48506.1 - 3.1e-35 122.0 3.9 3.1e-35 122.0 3.9 1.5 2 0 0 2 2 2 1 GPI biosynthesis protein family Pig-F Pro-kuma_activ PF09286.11 KIK48507.1 - 2.3e-36 125.2 0.1 4.4e-36 124.3 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Ribosomal_L34e PF01199.18 KIK48508.1 - 3.3e-42 142.7 2.7 4.7e-42 142.2 2.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.8 KIK48508.1 - 0.22 11.5 4.3 2.4 8.2 0.4 2.6 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Tetraspanin PF00335.20 KIK48509.1 - 0.009 15.8 4.7 0.009 15.8 4.7 1.5 1 1 0 1 1 1 1 Tetraspanin family EMP70 PF02990.16 KIK48509.1 - 0.14 10.8 2.1 0.22 10.2 2.1 1.3 1 0 0 1 1 1 0 Endomembrane protein 70 PepSY_TM PF03929.16 KIK48509.1 - 2 8.0 6.0 46 3.5 0.2 2.9 3 0 0 3 3 3 0 PepSY-associated TM region HSBP1 PF06825.12 KIK48510.1 - 0.014 15.3 0.8 0.054 13.4 0.8 1.9 1 1 0 1 1 1 0 Heat shock factor binding protein 1 MtrG PF04210.13 KIK48510.1 - 0.13 12.2 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G COG2 PF06148.11 KIK48511.1 - 0.00096 19.2 0.2 0.4 10.8 0.0 2.4 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Tropomyosin_1 PF12718.7 KIK48511.1 - 0.004 17.3 0.2 0.0057 16.8 0.2 1.2 1 0 0 1 1 1 1 Tropomyosin like Sec34 PF04136.15 KIK48511.1 - 0.0045 16.9 0.2 0.24 11.3 0.4 2.1 1 1 1 2 2 2 1 Sec34-like family Vac_Fusion PF02346.16 KIK48511.1 - 0.0059 16.2 0.2 0.035 13.7 0.1 2.3 2 0 0 2 2 2 1 Chordopoxvirus multifunctional envelope protein A27 NPV_P10 PF05531.12 KIK48511.1 - 0.0062 17.0 1.2 0.04 14.4 0.7 2.4 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 KIK48511.1 - 0.0072 16.4 0.7 0.019 15.0 0.7 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KIK48511.1 - 0.0095 16.2 0.5 1.7 9.0 0.3 2.2 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4795 PF16043.5 KIK48511.1 - 0.011 15.3 1.0 0.011 15.3 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) XhlA PF10779.9 KIK48511.1 - 0.035 14.3 1.0 9 6.6 0.0 2.3 2 0 0 2 2 2 0 Haemolysin XhlA ApoLp-III PF07464.11 KIK48511.1 - 0.043 13.9 0.1 0.085 12.9 0.1 1.6 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Tektin PF03148.14 KIK48511.1 - 0.043 12.6 0.2 0.061 12.1 0.2 1.2 1 0 0 1 1 1 0 Tektin family DUF948 PF06103.11 KIK48511.1 - 0.056 13.7 0.6 0.68 10.2 0.4 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 KIK48511.1 - 0.071 13.1 0.8 0.38 10.8 0.8 2.0 1 1 0 1 1 1 0 Laminin Domain II IFT57 PF10498.9 KIK48511.1 - 0.075 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CdvA PF18822.1 KIK48511.1 - 0.092 12.6 0.5 0.63 9.9 0.0 2.1 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Spc7 PF08317.11 KIK48511.1 - 0.1 11.4 0.4 0.13 11.1 0.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HisKA PF00512.25 KIK48511.1 - 0.11 12.6 0.1 6.5 6.9 0.1 2.4 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain DUF573 PF04504.14 KIK48511.1 - 0.11 13.2 0.2 0.5 11.1 0.1 1.9 1 1 0 2 2 2 0 Protein of unknown function, DUF573 HWE_HK PF07536.14 KIK48511.1 - 0.13 13.0 0.0 0.69 10.7 0.0 2.1 1 1 1 2 2 2 0 HWE histidine kinase Fez1 PF06818.15 KIK48511.1 - 0.15 12.5 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Fez1 DHR10 PF18595.1 KIK48511.1 - 0.17 11.9 2.7 0.66 10.1 1.2 2.0 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DivIVA PF05103.13 KIK48511.1 - 0.66 10.1 2.6 21 5.2 0.2 2.4 3 0 0 3 3 2 0 DivIVA protein F-box-like PF12937.7 KIK48512.1 - 1.7e-05 24.6 5.2 1.7e-05 24.6 5.2 2.9 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIK48512.1 - 1.6 8.7 5.0 21 5.1 0.3 3.3 3 0 0 3 3 3 0 F-box domain SepSecS PF05889.13 KIK48513.1 - 0.23 10.1 0.1 0.31 9.7 0.1 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS WD40 PF00400.32 KIK48514.1 - 4.5e-19 68.4 8.1 1.1e-08 35.6 0.7 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK48514.1 - 0.0002 21.6 0.8 0.84 10.0 0.4 3.2 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK48514.1 - 0.0024 16.6 2.2 0.003 16.3 0.1 1.9 2 0 0 2 2 2 1 Nucleoporin Nup120/160 DUF1513 PF07433.11 KIK48514.1 - 0.16 11.0 0.1 3.3 6.7 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1513) WD40_like PF17005.5 KIK48514.1 - 0.22 10.8 0.0 15 4.8 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Aminotran_3 PF00202.21 KIK48515.1 - 0.0082 14.8 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III TraX PF05857.11 KIK48519.1 - 0.002 18.2 2.3 0.0026 17.9 2.3 1.1 1 0 0 1 1 1 1 TraX protein zf-U1 PF06220.12 KIK48520.1 - 0.063 13.1 0.5 0.13 12.1 0.5 1.5 1 0 0 1 1 1 0 U1 zinc finger Ribosomal_L31e PF01198.19 KIK48522.1 - 2.2e-39 133.5 0.7 2.8e-39 133.2 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e CFEM PF05730.11 KIK48523.1 - 8.6e-12 45.0 15.5 1e-11 44.8 15.5 1.1 1 0 0 1 1 1 1 CFEM domain TIL PF01826.17 KIK48523.1 - 0.39 11.0 8.9 0.69 10.2 8.9 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain CAP59_mtransfer PF11735.8 KIK48524.1 - 2e-68 230.6 0.1 2.6e-68 230.3 0.1 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 WW PF00397.26 KIK48526.1 - 4.2e-09 36.3 6.6 4.2e-09 36.3 6.6 2.0 2 0 0 2 2 2 1 WW domain Calici_coat PF00915.20 KIK48526.1 - 0.19 10.6 5.2 0.11 11.4 3.2 1.5 1 1 1 2 2 2 0 Calicivirus coat protein Usp PF00582.26 KIK48527.1 - 2.5e-16 60.4 0.0 3.5e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family DUF3052 PF11253.8 KIK48531.1 - 0.083 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) F-box PF00646.33 KIK48532.1 - 2.1e-06 27.4 0.7 4.6e-06 26.4 0.7 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK48532.1 - 0.001 18.9 1.5 0.0024 17.7 1.5 1.7 1 0 0 1 1 1 1 F-box-like EPSP_synthase PF00275.20 KIK48532.1 - 0.096 11.4 0.0 9.6 4.8 0.0 2.1 2 0 0 2 2 2 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Terminase_6 PF03237.15 KIK48532.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Terminase-like family LIF_OSM PF01291.17 KIK48533.1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 LIF / OSM family MMR_HSR1 PF01926.23 KIK48539.1 - 1.6e-05 25.0 0.0 2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KIK48539.1 - 0.00063 19.2 0.0 0.00081 18.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KIK48539.1 - 0.0014 18.8 0.1 0.0022 18.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KIK48539.1 - 0.0019 18.1 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase TniB PF05621.11 KIK48539.1 - 0.0072 15.8 0.0 0.0094 15.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein ATPase_2 PF01637.18 KIK48539.1 - 0.011 15.7 0.1 0.013 15.4 0.1 1.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 KIK48539.1 - 0.011 16.1 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KIK48539.1 - 0.012 15.1 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B G-alpha PF00503.20 KIK48539.1 - 0.013 14.7 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Septin PF00735.18 KIK48539.1 - 0.013 14.8 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Septin NB-ARC PF00931.22 KIK48539.1 - 0.033 13.4 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 KIK48539.1 - 0.05 13.3 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 KIK48539.1 - 0.05 12.7 0.0 0.061 12.4 0.0 1.1 1 0 0 1 1 1 0 MCM P-loop domain ABC_tran PF00005.27 KIK48539.1 - 0.061 13.8 0.0 0.072 13.6 0.0 1.2 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 KIK48539.1 - 0.077 12.7 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.25 KIK48539.1 - 0.091 12.4 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.15 KIK48539.1 - 0.093 12.6 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.6 KIK48539.1 - 0.18 11.6 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_membrane PF00664.23 KIK48540.1 - 2.8e-77 260.1 22.2 5.9e-42 144.2 8.3 3.0 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK48540.1 - 6e-55 185.5 0.0 6.3e-29 101.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIK48540.1 - 8.9e-14 51.4 2.8 0.00013 21.5 0.4 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIK48540.1 - 2.5e-08 34.5 0.2 0.00089 19.7 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 KIK48540.1 - 2.5e-08 33.8 0.0 0.91 9.2 0.0 4.4 4 0 0 4 4 4 2 IstB-like ATP binding protein AAA_21 PF13304.6 KIK48540.1 - 1.4e-06 28.3 0.5 2.7 7.7 0.0 4.2 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIK48540.1 - 1.5e-06 27.9 0.2 0.026 14.3 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KIK48540.1 - 8.1e-06 25.2 0.0 0.12 11.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.6 KIK48540.1 - 1.4e-05 25.4 0.7 0.058 13.7 0.2 3.8 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KIK48540.1 - 1.4e-05 24.9 0.8 0.22 11.2 0.1 2.9 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KIK48540.1 - 1.8e-05 24.7 0.0 0.15 11.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 KIK48540.1 - 0.00013 21.6 0.4 0.96 9.0 0.0 3.6 4 0 0 4 4 3 2 AAA domain ABC_ATPase PF09818.9 KIK48540.1 - 0.00014 20.9 0.0 0.0088 14.9 0.0 2.7 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_18 PF13238.6 KIK48540.1 - 0.00023 21.7 0.0 0.095 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KIK48540.1 - 0.00024 21.3 0.3 0.44 10.6 0.1 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_33 PF13671.6 KIK48540.1 - 0.00029 21.0 0.3 1.2 9.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KIK48540.1 - 0.00033 20.7 0.0 0.22 11.5 0.0 3.7 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KIK48540.1 - 0.0017 18.1 0.0 5.6 6.6 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain SbcCD_C PF13558.6 KIK48540.1 - 0.0019 18.4 0.1 1.3 9.4 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 KIK48540.1 - 0.0021 18.3 1.3 0.26 11.5 0.3 3.5 2 1 0 3 3 3 1 AAA domain PRK PF00485.18 KIK48540.1 - 0.0033 17.2 0.1 0.44 10.2 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_15 PF13175.6 KIK48540.1 - 0.011 15.4 0.0 3.2 7.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 KIK48540.1 - 0.017 14.7 0.0 3.7 7.0 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KIK48540.1 - 0.02 15.3 0.0 2.8 8.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.20 KIK48540.1 - 0.024 14.5 0.2 6.8 6.6 0.1 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase Mg_chelatase PF01078.21 KIK48540.1 - 0.032 13.6 0.0 5.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI G-alpha PF00503.20 KIK48540.1 - 0.046 12.9 0.0 0.89 8.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.6 KIK48540.1 - 0.054 13.2 0.0 3.9 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KIK48540.1 - 0.072 13.5 0.0 14 6.1 0.0 3.7 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KIK48540.1 - 0.075 12.4 0.1 14 4.9 0.0 2.5 2 0 0 2 2 2 0 KaiC Rad17 PF03215.15 KIK48540.1 - 0.085 12.8 0.0 2.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain FtsK_SpoIIIE PF01580.18 KIK48540.1 - 0.13 11.6 0.0 9.6 5.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP-synt_ab PF00006.25 KIK48540.1 - 0.16 11.6 0.0 1 8.9 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 KIK48540.1 - 0.18 11.0 0.6 2.2 7.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF3987 PF13148.6 KIK48540.1 - 0.24 10.4 2.5 2.4 7.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) AAA_23 PF13476.6 KIK48540.1 - 0.36 11.3 4.0 7.8 6.9 0.0 2.5 3 0 0 3 3 2 0 AAA domain RNase_PH PF01138.21 KIK48541.1 - 3e-28 98.9 0.0 5.8e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KIK48541.1 - 3.3e-08 33.4 0.0 7.2e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Pectinesterase PF01095.19 KIK48542.1 - 6e-36 123.7 1.0 3.8e-35 121.0 1.0 1.9 1 1 0 1 1 1 1 Pectinesterase p450 PF00067.22 KIK48543.1 - 1e-61 209.1 0.0 3.4e-43 148.1 0.0 3.0 2 1 0 2 2 2 2 Cytochrome P450 ParD PF09386.10 KIK48544.1 - 0.11 12.9 0.2 0.19 12.1 0.2 1.4 1 0 0 1 1 1 0 Antitoxin ParD Chitin_synth_2 PF03142.15 KIK48545.1 - 5.3e-236 784.3 0.4 7.4e-236 783.8 0.4 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KIK48545.1 - 3.5e-139 465.1 0.0 3.4e-138 461.8 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 KIK48545.1 - 9.4e-19 67.1 0.1 2.7e-18 65.6 0.1 1.8 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 KIK48545.1 - 1.4e-08 34.9 0.0 2.6e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KIK48545.1 - 8.2e-07 29.1 3.2 8.2e-07 29.1 3.2 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.28 KIK48545.1 - 1.4e-06 28.3 0.1 0.00078 19.5 0.0 3.2 2 1 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 KIK48545.1 - 0.0019 18.0 0.0 2.7 7.8 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 AAA_29 PF13555.6 KIK48545.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_hydro_71 PF03659.14 KIK48546.1 - 2.4e-117 391.9 16.2 2.7e-117 391.8 16.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 PTPA PF03095.15 KIK48547.1 - 8.1e-125 416.2 0.0 9.2e-125 416.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein MerR_2 PF13591.6 KIK48547.1 - 0.16 11.8 0.0 0.46 10.4 0.0 1.7 1 0 0 1 1 1 0 MerR HTH family regulatory protein DUF5049 PF16468.5 KIK48550.1 - 0.035 14.0 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5049) DUF2754 PF10953.8 KIK48550.1 - 8.8 6.7 7.7 2.5 8.4 0.8 3.1 2 2 0 2 2 2 0 Protein of unknown function (DUF2754) adh_short_C2 PF13561.6 KIK48551.1 - 2.2e-58 197.6 0.7 3e-58 197.2 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK48551.1 - 1e-49 168.7 1.3 1.4e-49 168.2 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK48551.1 - 2e-18 67.0 0.4 3.5e-18 66.2 0.4 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK48551.1 - 0.0041 16.6 0.2 0.006 16.1 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KIK48551.1 - 0.019 14.9 0.1 0.42 10.5 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LDcluster4 PF18306.1 KIK48551.1 - 0.073 12.7 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 SLOG cluster4 family GDP_Man_Dehyd PF16363.5 KIK48551.1 - 0.12 11.8 0.1 0.13 11.6 0.1 1.3 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase WD40 PF00400.32 KIK48553.1 - 5.6e-11 42.8 9.5 8.2e-06 26.5 0.4 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat PD40 PF07676.12 KIK48553.1 - 1.3e-06 28.2 0.2 0.36 10.8 0.0 3.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 KIK48553.1 - 0.002 18.4 0.0 1.7 9.0 0.0 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 KIK48553.1 - 0.0071 14.4 0.2 0.45 8.5 0.0 2.0 1 1 1 2 2 2 2 IKI3 family B_lectin PF01453.24 KIK48553.1 - 0.032 14.8 0.0 0.07 13.7 0.0 1.5 1 0 0 1 1 1 0 D-mannose binding lectin Nup160 PF11715.8 KIK48553.1 - 0.045 12.4 0.2 0.084 11.5 0.0 1.6 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK48553.1 - 0.066 12.2 0.1 0.31 10.0 0.0 2.0 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TFIIIC_delta PF12657.7 KIK48553.1 - 0.089 12.7 0.7 2.5 8.0 0.1 2.4 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term RCC1_2 PF13540.6 KIK48553.1 - 0.13 12.1 2.0 0.4 10.5 0.0 2.8 4 0 0 4 4 4 0 Regulator of chromosome condensation (RCC1) repeat DUF1115 PF06544.12 KIK48554.1 - 3.2e-06 27.3 0.0 3.7e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Acylphosphatase PF00708.18 KIK48554.1 - 0.03 14.7 0.0 0.036 14.5 0.0 1.1 1 0 0 1 1 1 0 Acylphosphatase DUF1295 PF06966.12 KIK48555.1 - 0.022 14.3 0.0 0.026 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) F-box-like PF12937.7 KIK48558.1 - 9e-07 28.7 1.0 2.3e-06 27.4 1.0 1.7 1 0 0 1 1 1 1 F-box-like Complex1_LYR PF05347.15 KIK48559.1 - 7.7e-13 48.3 0.1 9.6e-13 48.0 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) adh_short_C2 PF13561.6 KIK48560.1 - 1.8e-47 161.9 0.9 7.9e-38 130.3 1.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIK48560.1 - 4.8e-42 143.6 0.3 7e-42 143.1 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIK48560.1 - 8.4e-17 61.6 0.3 1.2e-16 61.2 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK48560.1 - 0.0029 17.1 0.2 0.0052 16.3 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF4170 PF13773.6 KIK48560.1 - 0.1 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4170) SURF6 PF04935.12 KIK48561.1 - 4.3e-42 144.2 42.6 4.3e-42 144.2 42.6 2.3 2 0 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 KIK48561.1 - 2.6e-20 72.8 7.0 2.6e-20 72.8 7.0 5.4 5 1 0 5 5 5 1 60S ribosome biogenesis protein Rrp14 DUF4407 PF14362.6 KIK48561.1 - 3.1 7.1 31.7 0.46 9.8 8.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) WD40 PF00400.32 KIK48563.1 - 8.5e-112 361.9 71.6 5e-10 39.8 0.2 15.2 14 1 1 15 15 15 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK48563.1 - 1.7e-41 140.4 1.4 0.0089 16.3 0.0 12.3 1 1 12 14 14 14 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK48563.1 - 3e-28 98.7 14.9 0.0043 16.1 0.0 12.5 3 3 11 14 14 14 10 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIK48563.1 - 1.5e-19 70.7 0.7 1.7e-05 24.8 0.0 5.4 3 1 2 5 5 5 5 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KIK48563.1 - 3.7e-08 33.1 17.2 7.7 6.6 0.0 10.8 12 0 0 12 12 12 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KIK48563.1 - 9.7e-08 31.1 17.2 2 7.0 0.1 8.5 2 2 7 10 10 10 5 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK48563.1 - 2.3e-07 30.5 0.0 2.3 7.5 0.0 6.5 5 2 1 7 7 7 3 WD40-like domain Nbas_N PF15492.6 KIK48563.1 - 0.0018 17.6 10.4 1.9 7.7 0.1 6.7 6 2 3 9 9 9 2 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 KIK48563.1 - 0.0041 15.5 0.0 1.1 7.5 0.0 4.1 4 2 1 5 5 5 1 WD repeat-containing and planar cell polarity effector protein Fritz VWA_2 PF13519.6 KIK48564.1 - 1.3e-12 48.3 0.1 4.3e-12 46.6 0.1 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain RHD3 PF05879.12 KIK48564.1 - 4.8e-07 28.3 0.2 7.6e-07 27.7 0.2 1.2 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) VWA_CoxE PF05762.14 KIK48564.1 - 9.2e-07 28.5 2.6 3e-05 23.5 0.5 3.2 3 0 0 3 3 3 1 VWA domain containing CoxE-like protein GBP PF02263.19 KIK48564.1 - 1.2e-05 24.7 0.1 2.4e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain VWA PF00092.28 KIK48564.1 - 4e-05 23.9 0.0 0.00016 22.0 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain YrhC PF14143.6 KIK48566.1 - 1.5 8.9 6.8 0.56 10.3 1.2 2.7 2 1 0 2 2 2 0 YrhC-like protein DUF4661 PF15576.6 KIK48569.1 - 0.043 13.7 0.6 0.089 12.7 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Ilm1 PF10311.9 KIK48571.1 - 0.024 14.3 0.3 0.058 13.0 0.3 1.8 1 1 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 SpoIIIAC PF06686.11 KIK48574.1 - 8.2 6.7 9.3 5.9 7.2 0.8 2.8 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family HIT PF01230.23 KIK48577.1 - 5.1e-21 75.2 0.0 7.2e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KIK48577.1 - 4.6e-14 52.9 0.0 6.3e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KIK48577.1 - 0.0001 22.2 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Molybdopterin PF00384.22 KIK48578.1 - 2.9e-66 224.2 0.0 1.7e-65 221.7 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KIK48578.1 - 8.4e-20 70.6 0.3 2.6e-19 69.0 0.3 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 KIK48578.1 - 2.7e-17 62.0 0.2 2.7e-17 62.0 0.2 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 KIK48578.1 - 2.3e-16 60.2 0.2 5.6e-16 59.0 0.2 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 KIK48578.1 - 7.8e-09 35.4 0.6 7.8e-09 35.4 0.6 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KIK48578.1 - 0.025 14.3 0.1 0.54 10.0 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 KIK48578.1 - 0.17 11.7 1.1 4.8 7.2 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Glyco_transf_90 PF05686.12 KIK48581.1 - 2.4e-14 53.1 0.1 5.6e-09 35.4 0.0 3.5 3 1 0 3 3 3 2 Glycosyl transferase family 90 adh_short PF00106.25 KIK48582.1 - 2.3e-46 157.7 0.1 3e-46 157.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK48582.1 - 3.1e-32 112.0 0.0 4.2e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK48582.1 - 1.1e-14 54.8 0.2 1.5e-14 54.3 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KIK48582.1 - 3.6e-05 23.8 0.0 5.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIK48582.1 - 0.00031 20.3 0.5 0.00077 19.0 0.5 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KIK48582.1 - 0.0019 17.8 0.3 0.0029 17.2 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KIK48582.1 - 0.0029 17.1 0.1 0.005 16.3 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIK48582.1 - 0.013 14.7 0.1 0.017 14.2 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KIK48582.1 - 0.046 12.8 0.0 0.061 12.4 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.17 KIK48582.1 - 0.074 13.6 0.1 0.19 12.3 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 KIK48583.1 - 1.2e-05 24.9 0.1 1.3e-05 24.7 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK48583.1 - 2.1e-05 24.2 0.1 2.2e-05 24.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF3671 PF12420.8 KIK48585.1 - 0.18 11.9 0.2 0.18 11.9 0.2 2.2 1 1 0 2 2 2 0 Protein of unknown function Nop53 PF07767.11 KIK48587.1 - 1.7e-95 320.8 15.6 2e-95 320.5 15.6 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Mobilization_B PF17511.2 KIK48587.1 - 3.3 8.1 7.9 1.5 9.1 3.7 2.4 2 1 0 2 2 2 0 Mobilization protein B RPN7 PF10602.9 KIK48588.1 - 1.3e-41 142.2 0.1 2.3e-41 141.4 0.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KIK48588.1 - 4.7e-16 59.2 1.8 9.7e-16 58.2 0.2 2.3 3 0 0 3 3 3 1 PCI domain TPR_12 PF13424.6 KIK48588.1 - 5.3e-05 23.4 0.0 0.003 17.8 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK48588.1 - 6.2e-05 22.8 0.4 0.019 15.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIK48588.1 - 0.00022 21.1 0.1 0.28 11.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF2119 PF09892.9 KIK48588.1 - 0.00089 18.7 1.2 0.0035 16.7 0.4 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2119) Ins_allergen_rp PF06757.13 KIK48588.1 - 0.0058 16.6 0.3 0.016 15.2 0.3 1.8 2 0 0 2 2 2 1 Insect allergen related repeat, nitrile-specifier detoxification TPR_1 PF00515.28 KIK48588.1 - 0.015 15.1 0.4 0.25 11.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIK48588.1 - 0.2 12.6 2.5 12 7.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat VWA_2 PF13519.6 KIK48589.1 - 9e-12 45.6 0.3 3.3e-11 43.8 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain RHD3 PF05879.12 KIK48589.1 - 9.8e-07 27.3 0.2 9.8e-07 27.3 0.2 1.5 2 0 0 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) VWA_CoxE PF05762.14 KIK48589.1 - 3e-05 23.5 3.6 0.00026 20.5 0.3 3.3 3 0 0 3 3 3 1 VWA domain containing CoxE-like protein GBP PF02263.19 KIK48589.1 - 3.6e-05 23.2 1.5 7.1e-05 22.2 0.1 2.0 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain VWA PF00092.28 KIK48589.1 - 0.00015 22.1 0.0 0.00055 20.2 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain Asp_Arg_Hydrox PF05118.15 KIK48589.1 - 0.018 14.9 0.5 1.5 8.7 0.5 2.9 3 0 0 3 3 3 0 Aspartyl/Asparaginyl beta-hydroxylase PgaPase_1 PF06162.12 KIK48589.1 - 0.044 13.5 0.6 0.97 9.2 0.0 2.9 3 0 0 3 3 3 0 Putative pyroglutamyl peptidase PgaPase_1 T4_baseplate PF12322.8 KIK48589.1 - 0.11 12.0 0.1 0.31 10.5 0.1 1.7 1 0 0 1 1 1 0 T4 bacteriophage base plate protein GRDP-like PF07173.12 KIK48591.1 - 4.2e-23 82.6 0.2 3e-16 60.3 0.0 3.2 2 1 1 3 3 3 3 Glycine-rich domain-containing protein-like MMR_HSR1 PF01926.23 KIK48592.1 - 2.5e-12 46.9 0.0 6.3e-12 45.6 0.0 1.7 1 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK48592.1 - 3.8e-07 29.7 0.0 5.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KIK48592.1 - 1.4e-06 28.3 0.1 4.5e-06 26.7 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase Ras PF00071.22 KIK48592.1 - 2.3e-05 24.0 0.1 0.00024 20.7 0.1 2.1 2 0 0 2 2 2 1 Ras family ABC_tran PF00005.27 KIK48592.1 - 8.5e-05 23.1 0.1 0.00018 22.0 0.1 1.6 1 0 0 1 1 1 1 ABC transporter Roc PF08477.13 KIK48592.1 - 0.00019 21.6 0.1 0.0008 19.6 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KIK48592.1 - 0.00025 21.1 0.0 0.063 13.3 0.1 2.5 1 1 1 2 2 2 1 Dynamin family AAA_16 PF13191.6 KIK48592.1 - 0.0008 19.8 0.0 0.0013 19.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KIK48592.1 - 0.002 18.5 0.0 0.004 17.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase TniB PF05621.11 KIK48592.1 - 0.0048 16.3 0.0 0.0076 15.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 KIK48592.1 - 0.0061 16.8 0.1 0.015 15.6 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KIK48592.1 - 0.018 15.5 0.0 0.03 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIK48592.1 - 0.028 14.2 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KIK48592.1 - 0.032 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD PF00270.29 KIK48592.1 - 0.034 13.9 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase Sigma54_activat PF00158.26 KIK48592.1 - 0.047 13.4 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Septin PF00735.18 KIK48592.1 - 0.061 12.6 0.0 0.14 11.4 0.0 1.5 2 0 0 2 2 2 0 Septin FeoB_N PF02421.18 KIK48592.1 - 0.061 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B ATP-synt_ab PF00006.25 KIK48592.1 - 0.065 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.13 KIK48592.1 - 0.073 12.2 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF87 PF01935.17 KIK48592.1 - 0.094 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain IstB_IS21 PF01695.17 KIK48592.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TPR_19 PF14559.6 KIK48593.1 - 0.12 13.0 0.0 1.2 9.6 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat RHD3 PF05879.12 KIK48594.1 - 2.9e-07 29.0 0.1 5.4e-07 28.2 0.1 1.5 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KIK48594.1 - 2.2e-05 23.8 0.1 4.6e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MHCassoc_trimer PF08831.10 KIK48594.1 - 0.2 11.7 0.2 14 5.8 0.0 3.2 3 0 0 3 3 3 0 Class II MHC-associated invariant chain trimerisation domain VWA_2 PF13519.6 KIK48596.1 - 5.5e-10 39.8 0.4 1.5e-09 38.5 0.4 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KIK48596.1 - 0.0008 19.4 0.3 0.0076 16.2 0.1 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KIK48596.1 - 0.0025 18.1 0.1 0.0077 16.5 0.1 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain GRDP-like PF07173.12 KIK48597.1 - 3.5e-23 82.8 0.1 4.2e-16 59.9 0.0 3.2 2 1 1 3 3 3 3 Glycine-rich domain-containing protein-like MMR_HSR1 PF01926.23 KIK48598.1 - 3.3e-09 36.8 0.0 6.7e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK48598.1 - 7.6e-06 25.4 0.6 8.3e-06 25.3 0.1 1.5 2 1 0 2 2 2 1 AIG1 family Roc PF08477.13 KIK48598.1 - 2e-05 24.8 0.1 0.0034 17.6 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KIK48598.1 - 5e-05 22.8 0.0 0.0052 16.2 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein AAA_16 PF13191.6 KIK48598.1 - 0.0002 21.8 0.0 0.00032 21.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 KIK48598.1 - 0.00041 20.4 1.2 0.024 14.7 0.3 2.5 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KIK48598.1 - 0.0015 18.5 0.0 0.0036 17.2 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase Ras PF00071.22 KIK48598.1 - 0.0026 17.4 0.0 0.0074 15.9 0.0 1.7 2 0 0 2 2 2 1 Ras family IIGP PF05049.13 KIK48598.1 - 0.0062 15.6 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 KIK48598.1 - 0.019 15.5 0.3 0.069 13.7 0.0 2.0 2 1 0 2 2 2 0 ABC transporter Septin PF00735.18 KIK48598.1 - 0.024 13.9 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_23 PF13476.6 KIK48598.1 - 0.094 13.2 0.0 0.39 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KIK48598.1 - 0.11 12.7 0.1 0.39 11.0 0.0 2.1 2 2 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KIK48599.1 - 3.5e-07 30.3 0.1 6.3e-07 29.5 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK48599.1 - 0.0059 15.9 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KIK48599.1 - 0.17 11.8 0.4 0.45 10.4 0.1 1.9 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 KIK48599.1 - 0.19 11.7 1.7 6.8 6.7 0.7 2.4 1 1 1 2 2 2 0 Dynamin family PDDEXK_6 PF04720.12 KIK48600.1 - 0.15 12.0 0.1 0.17 11.8 0.1 1.1 1 0 0 1 1 1 0 PDDEXK-like family of unknown function TPR_10 PF13374.6 KIK48602.1 - 7.5e-05 22.5 0.5 0.04 13.8 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat CAP_N PF01213.19 KIK48602.1 - 0.42 10.1 1.5 0.51 9.8 1.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MSA-2c PF12238.8 KIK48602.1 - 0.48 10.4 2.3 0.64 10.0 2.3 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c MMR_HSR1 PF01926.23 KIK48603.1 - 5.2e-12 45.9 0.0 7.6e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK48603.1 - 1.7e-07 30.8 0.0 2.3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIK48603.1 - 1.3e-06 28.6 0.1 0.0002 21.4 0.5 2.2 1 1 1 2 2 2 1 Dynamin family Roc PF08477.13 KIK48603.1 - 2.9e-06 27.5 0.1 1e-05 25.7 0.0 1.9 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KIK48603.1 - 4.4e-06 26.4 0.3 2.4e-05 24.0 0.2 1.9 2 0 0 2 2 2 1 Ras family RsgA_GTPase PF03193.16 KIK48603.1 - 0.00056 19.9 0.1 0.0015 18.4 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KIK48603.1 - 0.00095 19.6 0.0 0.0018 18.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KIK48603.1 - 0.0014 18.4 0.2 0.0027 17.4 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KIK48603.1 - 0.0019 18.7 0.1 0.0021 18.6 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 KIK48603.1 - 0.0025 18.3 0.3 0.0049 17.4 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIK48603.1 - 0.0089 16.3 0.0 0.016 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIK48603.1 - 0.014 15.8 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_13 PF13166.6 KIK48603.1 - 0.015 14.0 0.8 0.044 12.4 0.1 2.0 2 1 0 2 2 2 0 AAA domain IIGP PF05049.13 KIK48603.1 - 0.017 14.2 0.1 0.024 13.7 0.1 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ATP_bind_1 PF03029.17 KIK48603.1 - 0.019 14.7 0.1 2.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 KIK48603.1 - 0.019 14.2 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 KIK48603.1 - 0.026 14.0 0.2 0.089 12.2 0.1 2.1 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF815 PF05673.13 KIK48603.1 - 0.035 13.3 0.1 0.063 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 KIK48603.1 - 0.039 14.5 0.4 0.2 12.2 0.1 2.3 1 1 0 2 2 2 0 AAA domain FeoB_N PF02421.18 KIK48603.1 - 0.044 13.3 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B SMC_N PF02463.19 KIK48603.1 - 0.059 12.8 0.2 0.1 12.0 0.2 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KIK48603.1 - 0.097 12.6 0.0 0.74 9.7 0.0 2.1 1 1 1 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.18 KIK48603.1 - 0.097 12.0 0.3 0.23 10.8 0.1 1.7 2 1 0 2 2 2 0 FtsK/SpoIIIE family ATPase_2 PF01637.18 KIK48603.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 KIK48603.1 - 0.13 12.5 0.1 0.31 11.3 0.1 1.7 1 1 1 2 2 2 0 AAA domain PRK PF00485.18 KIK48603.1 - 0.14 11.9 0.2 0.23 11.2 0.2 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_21 PF13304.6 KIK48603.1 - 0.15 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system TniB PF05621.11 KIK48603.1 - 0.17 11.3 0.0 0.42 10.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA PF00004.29 KIK48603.1 - 0.17 12.3 0.1 0.34 11.4 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIK48603.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region F-box-like PF12937.7 KIK48604.1 - 0.012 15.5 0.0 0.036 14.0 0.0 1.9 1 0 0 1 1 1 0 F-box-like MMR_HSR1 PF01926.23 KIK48605.1 - 1.2e-11 44.7 0.0 2.2e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK48605.1 - 2.8e-05 23.6 0.0 4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 KIK48605.1 - 0.00013 22.5 0.0 0.00023 21.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KIK48605.1 - 0.00026 20.9 0.0 0.00075 19.4 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 KIK48605.1 - 0.00086 19.9 0.1 0.0014 19.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 KIK48605.1 - 0.00099 19.3 0.1 0.003 17.7 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KIK48605.1 - 0.0011 19.0 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Ras PF00071.22 KIK48605.1 - 0.0013 18.3 0.1 0.0042 16.7 0.1 1.8 2 0 0 2 2 2 1 Ras family AAA_16 PF13191.6 KIK48605.1 - 0.0042 17.5 0.0 0.0084 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIK48605.1 - 0.0045 17.3 0.1 0.02 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIK48605.1 - 0.0051 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 KIK48605.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KIK48605.1 - 0.015 14.8 0.1 0.083 12.4 0.0 2.2 3 0 0 3 3 3 0 P-loop containing dynein motor region DUF815 PF05673.13 KIK48605.1 - 0.03 13.5 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 KIK48605.1 - 0.04 13.3 0.0 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.29 KIK48605.1 - 0.052 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KIK48605.1 - 0.057 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.20 KIK48605.1 - 0.061 12.4 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 KIK48605.1 - 0.075 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Septin PF00735.18 KIK48605.1 - 0.092 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Septin ATP-synt_ab PF00006.25 KIK48605.1 - 0.11 12.1 0.0 0.31 10.7 0.0 1.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain C2 PF00168.30 KIK48605.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 C2 domain IIGP PF05049.13 KIK48605.1 - 0.14 11.2 0.1 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF87 PF01935.17 KIK48605.1 - 0.15 12.1 0.1 0.26 11.4 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain TniB PF05621.11 KIK48605.1 - 0.2 11.1 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein MMR_HSR1 PF01926.23 KIK48607.1 - 3.9e-13 49.5 0.0 6e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK48607.1 - 1e-08 34.8 0.0 1.3e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIK48607.1 - 4.4e-07 30.1 0.1 0.0082 16.2 0.1 2.4 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 KIK48607.1 - 1.5e-05 24.9 0.0 2.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KIK48607.1 - 0.00017 22.0 0.0 0.00038 20.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.17 KIK48607.1 - 0.00069 19.8 0.1 0.0013 18.9 0.1 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 KIK48607.1 - 0.002 18.4 0.0 0.0034 17.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 KIK48607.1 - 0.002 17.5 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family RNA_helicase PF00910.22 KIK48607.1 - 0.0026 18.1 0.0 0.0049 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase ATP_bind_1 PF03029.17 KIK48607.1 - 0.0032 17.3 0.0 0.34 10.6 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KIK48607.1 - 0.0036 16.8 0.0 0.011 15.2 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit NACHT PF05729.12 KIK48607.1 - 0.0046 16.9 0.0 0.015 15.2 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 KIK48607.1 - 0.006 16.3 0.0 0.021 14.6 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Roc PF08477.13 KIK48607.1 - 0.0099 16.1 0.1 0.033 14.4 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 KIK48607.1 - 0.011 16.2 0.0 0.018 15.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIK48607.1 - 0.016 15.7 0.0 0.027 15.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 KIK48607.1 - 0.036 13.6 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 KIK48607.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 KIK48607.1 - 0.071 12.5 0.0 0.15 11.4 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein Sigma54_activat PF00158.26 KIK48607.1 - 0.079 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Ras PF00071.22 KIK48607.1 - 0.082 12.5 0.0 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 Ras family IIGP PF05049.13 KIK48607.1 - 0.088 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 KIK48607.1 - 0.091 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KIK48607.1 - 0.095 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Septin ATPase_2 PF01637.18 KIK48607.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea GTP_EFTU PF00009.27 KIK48607.1 - 0.1 12.1 0.0 1.5 8.4 0.0 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF815 PF05673.13 KIK48607.1 - 0.11 11.7 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) BclA_C PF18573.1 KIK48607.1 - 0.13 12.2 0.9 0.17 11.8 0.1 1.6 2 0 0 2 2 2 0 BclA C-terminal domain T2SSE PF00437.20 KIK48607.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Pkinase_Tyr PF07714.17 KIK48608.1 - 1.4e-36 126.2 0.0 2e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIK48608.1 - 2.2e-34 119.1 0.0 3.5e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain MMR_HSR1 PF01926.23 KIK48608.1 - 4.2e-13 49.4 0.0 6.9e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK48608.1 - 1.7e-07 30.8 0.1 2.6e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIK48608.1 - 0.00014 22.0 0.3 0.00081 19.5 0.2 2.0 1 1 1 2 2 2 1 Dynamin family AAA_23 PF13476.6 KIK48608.1 - 0.0004 20.9 0.1 0.00069 20.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain Kdo PF06293.14 KIK48608.1 - 0.00049 19.5 0.0 0.0025 17.2 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RsgA_GTPase PF03193.16 KIK48608.1 - 0.00051 20.0 0.2 0.00093 19.1 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 KIK48608.1 - 0.00087 19.8 0.1 0.0017 18.9 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KIK48608.1 - 0.00099 18.8 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KIK48608.1 - 0.002 18.5 0.0 0.0034 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 KIK48608.1 - 0.0051 17.0 0.2 0.019 15.1 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KIK48608.1 - 0.0056 16.9 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KIK48608.1 - 0.006 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein APH PF01636.23 KIK48608.1 - 0.0068 16.4 0.0 0.019 14.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family FtsK_SpoIIIE PF01580.18 KIK48608.1 - 0.012 15.0 0.0 0.082 12.3 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Septin PF00735.18 KIK48608.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 KIK48608.1 - 0.023 14.1 0.0 0.044 13.2 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit RNA_helicase PF00910.22 KIK48608.1 - 0.027 14.9 0.0 0.052 13.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KIK48608.1 - 0.03 13.8 0.1 0.088 12.3 0.1 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KIK48608.1 - 0.038 13.7 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Ras PF00071.22 KIK48608.1 - 0.052 13.1 0.1 0.089 12.4 0.1 1.3 1 0 0 1 1 1 0 Ras family DUF815 PF05673.13 KIK48608.1 - 0.058 12.5 0.0 0.092 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SMC_N PF02463.19 KIK48608.1 - 0.063 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 KIK48608.1 - 0.069 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA PF00004.29 KIK48608.1 - 0.091 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KIK48608.1 - 0.12 11.4 0.1 0.22 10.6 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RIO1 PF01163.22 KIK48608.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family IIGP PF05049.13 KIK48608.1 - 0.13 11.3 0.1 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Seadorna_VP7 PF07387.11 KIK48608.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Y_phosphatase PF00102.27 KIK48608.1 - 0.15 11.6 0.1 0.44 10.1 0.1 1.7 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Sigma54_activat PF00158.26 KIK48608.1 - 0.19 11.4 0.1 0.39 10.4 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 KIK48608.1 - 0.2 11.6 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea WD40 PF00400.32 KIK48611.1 - 2.7e-120 388.8 53.6 1.5e-09 38.3 0.5 14.7 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK48611.1 - 9.6e-46 154.0 0.0 0.055 13.8 0.0 13.7 1 1 12 13 13 13 13 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK48611.1 - 2.4e-29 102.3 11.8 0.065 12.2 0.0 13.0 6 5 6 13 13 13 9 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK48611.1 - 1.3e-12 47.2 3.6 4.5 5.8 0.0 10.5 7 2 4 12 12 12 3 Nucleoporin Nup120/160 PD40 PF07676.12 KIK48611.1 - 3.3e-11 42.8 29.9 1.7 8.7 0.1 13.0 15 0 0 15 15 13 3 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KIK48611.1 - 9.8e-11 41.5 0.0 0.067 12.5 0.0 8.3 8 2 0 9 9 9 1 WD40-like domain PQQ_2 PF13360.6 KIK48611.1 - 1.7e-06 27.8 14.7 2e-05 24.3 2.7 4.0 1 1 3 5 5 5 2 PQQ-like domain Nbas_N PF15492.6 KIK48611.1 - 1.7e-06 27.6 6.2 4.3 6.6 0.0 7.1 8 0 0 8 8 8 2 Neuroblastoma-amplified sequence, N terminal AAA_16 PF13191.6 KIK48611.1 - 2.4e-06 28.0 0.0 6.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIK48611.1 - 7.4e-06 26.0 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Frtz PF11768.8 KIK48611.1 - 2.7e-05 22.7 0.0 7.4 4.8 0.0 5.9 3 3 3 6 6 6 1 WD repeat-containing and planar cell polarity effector protein Fritz AAA_22 PF13401.6 KIK48611.1 - 0.013 15.8 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KIK48611.1 - 0.014 14.5 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PQQ PF01011.21 KIK48611.1 - 0.036 14.0 0.1 1.5 8.9 0.0 3.9 5 0 0 5 5 4 0 PQQ enzyme repeat CHAP PF05257.16 KIK48611.1 - 0.095 13.3 16.4 9.7 6.9 0.0 8.3 4 2 4 9 9 9 0 CHAP domain NB-ARC PF00931.22 KIK48611.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 KIK48611.1 - 0.14 12.5 0.0 0.59 10.6 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KIK48611.1 - 0.15 12.5 0.0 0.44 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Peptidase_S9_N PF02897.15 KIK48611.1 - 0.2 10.4 0.0 3.6 6.3 0.0 3.0 3 0 0 3 3 3 0 Prolyl oligopeptidase, N-terminal beta-propeller domain FHA PF00498.26 KIK48612.1 - 2.9e-05 24.3 0.0 5.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIK48612.1 - 0.0011 19.2 0.0 0.0038 17.5 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF1761 PF08570.10 KIK48614.1 - 0.43 10.8 12.0 2.1 8.6 0.4 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1761) N2227 PF07942.12 KIK48615.1 - 1.4e-96 322.9 0.0 1.9e-96 322.4 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 KIK48615.1 - 0.001 19.7 0.0 0.043 14.5 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK48615.1 - 0.0014 19.4 0.0 0.0072 17.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK48615.1 - 0.0063 16.4 0.0 0.016 15.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK48615.1 - 0.18 12.5 0.0 2.7 8.7 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase domain Sugar_tr PF00083.24 KIK48617.1 - 1.2e-106 357.3 27.6 1.5e-106 357.0 27.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIK48617.1 - 1.4e-23 83.4 30.7 1.4e-23 83.4 30.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.15 KIK48617.1 - 0.044 13.7 5.9 0.068 13.0 3.0 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain PT-VENN PF04829.13 KIK48617.1 - 0.12 12.4 0.1 0.39 10.8 0.1 1.9 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Abhydrolase_6 PF12697.7 KIK48618.1 - 6.4e-20 72.7 0.4 8.9e-20 72.2 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIK48618.1 - 4.3e-12 46.2 0.0 7.5e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK48618.1 - 1.2e-10 41.1 0.0 2.2e-10 40.2 0.0 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KIK48618.1 - 0.00055 18.9 0.1 0.0018 17.3 0.1 1.7 1 1 0 1 1 1 1 Chlorophyllase enzyme PGAP1 PF07819.13 KIK48618.1 - 0.0036 17.1 0.0 0.0056 16.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 KIK48618.1 - 0.0057 16.5 0.0 0.0082 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase PF07224.11 KIK48618.1 - 0.031 13.3 0.0 0.23 10.4 0.0 1.9 1 1 0 1 1 1 0 Chlorophyllase FSH1 PF03959.13 KIK48618.1 - 0.12 12.0 0.0 0.63 9.7 0.0 1.9 1 1 1 2 2 2 0 Serine hydrolase (FSH1) Esterase PF00756.20 KIK48618.1 - 0.15 11.7 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Isy1 PF06246.12 KIK48619.1 - 7.5e-93 310.8 1.8 1.2e-92 310.2 1.8 1.3 1 0 0 1 1 1 1 Isy1-like splicing family Glyco_hydro_3_C PF01915.22 KIK48620.1 - 3.8e-44 151.1 0.1 5.6e-44 150.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIK48620.1 - 4e-32 111.9 0.0 1e-31 110.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIK48620.1 - 3.6e-05 23.8 0.0 7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Pkinase PF00069.25 KIK48621.1 - 6.9e-41 140.4 0.0 1e-40 139.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK48621.1 - 8.6e-18 64.5 0.0 1.2e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK48621.1 - 0.00031 20.1 0.0 0.00057 19.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIK48621.1 - 0.001 17.9 0.0 0.0015 17.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIK48621.1 - 0.0014 18.1 0.2 0.0022 17.4 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIK48621.1 - 0.0031 16.5 0.0 0.0044 16.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIK48621.1 - 0.056 13.3 0.1 0.4 10.5 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Arteri_Gl PF00951.18 KIK48622.1 - 0.094 12.5 5.0 0.21 11.4 5.0 1.6 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein JAB PF01398.21 KIK48623.1 - 6.6e-16 58.4 0.0 1.2e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KIK48623.1 - 4.5e-07 29.7 0.0 1.3e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.11 KIK48623.1 - 0.012 15.8 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 USP8 dimerisation domain PP2C PF00481.21 KIK48624.1 - 1.4e-22 80.6 0.0 1.1e-21 77.6 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KIK48624.1 - 0.00016 21.4 0.0 0.001 18.8 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KIK48624.1 - 0.078 12.9 0.0 2.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Terpene_synth_C PF03936.16 KIK48626.1 - 2.9e-05 23.6 0.0 4.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain zf-MYND PF01753.18 KIK48627.1 - 2.6e-10 40.2 15.2 2.6e-10 40.2 15.2 1.9 2 0 0 2 2 2 1 MYND finger Rhodanese_C PF12368.8 KIK48627.1 - 0.02 15.2 6.2 0.02 15.2 6.2 2.0 2 0 0 2 2 2 0 Rhodanase C-terminal zf-Nse PF11789.8 KIK48627.1 - 0.12 12.3 0.0 0.12 12.3 0.0 2.8 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit NUFIP1 PF10453.9 KIK48627.1 - 0.13 12.1 0.6 4.8 7.1 0.1 2.4 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C6H2 PF15801.5 KIK48627.1 - 1.4 9.3 18.6 0.042 14.1 11.8 2.1 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Abhydrolase_1 PF00561.20 KIK48628.1 - 9e-16 58.3 0.0 2.1e-15 57.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIK48628.1 - 3.3e-09 36.4 0.0 5.2e-09 35.7 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIK48628.1 - 2e-08 35.1 0.1 2.5e-08 34.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KIK48628.1 - 0.0018 18.4 0.1 0.003 17.7 0.1 1.4 1 1 0 1 1 1 1 Thioesterase domain DUF3530 PF12048.8 KIK48628.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) aGPT-Pplase1 PF18723.1 KIK48631.1 - 3.5e-100 335.1 0.0 4.5e-100 334.7 0.0 1.1 1 0 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 Chromo PF00385.24 KIK48631.1 - 7e-12 45.1 0.1 1.8e-11 43.8 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MFS_1 PF07690.16 KIK48632.1 - 2.5e-37 128.6 24.0 4.1e-37 127.9 24.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KIK48632.1 - 8.5e-05 22.0 10.0 0.00013 21.4 2.3 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF1772 PF08592.11 KIK48632.1 - 0.0072 16.6 4.4 0.056 13.8 0.0 3.4 2 2 0 2 2 2 1 Domain of unknown function (DUF1772) OSTbeta PF15048.6 KIK48632.1 - 0.0096 16.1 0.1 0.028 14.5 0.0 1.8 2 0 0 2 2 2 1 Organic solute transporter subunit beta protein DC_STAMP PF07782.13 KIK48632.1 - 0.035 13.9 0.2 0.085 12.7 0.2 1.7 1 0 0 1 1 1 0 DC-STAMP-like protein MPS-4 PF17523.2 KIK48632.1 - 0.066 13.4 0.2 0.33 11.1 0.2 2.2 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 DUF4181 PF13789.6 KIK48632.1 - 0.13 12.6 0.1 0.13 12.6 0.1 3.9 5 0 0 5 5 5 0 Domain of unknown function (DUF4181) Sugarporin_N PF11471.8 KIK48632.1 - 0.13 12.2 0.1 0.51 10.3 0.1 2.0 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Thiolase_N PF00108.23 KIK48633.1 - 7.9e-85 284.3 1.4 1.2e-84 283.8 1.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIK48633.1 - 2.6e-39 133.7 0.8 2.6e-39 133.7 0.8 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIK48633.1 - 0.38 10.3 8.7 0.058 13.0 2.6 2.3 2 1 1 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain Autophagy_act_C PF03987.15 KIK48634.1 - 4.3e-17 62.5 0.3 8.1e-17 61.6 0.3 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Ribosomal_S3Ae PF01015.18 KIK48635.1 - 7.6e-96 319.5 3.5 9.1e-96 319.2 3.5 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 KIK48635.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Pribosyltran PF00156.27 KIK48636.1 - 4.2e-14 52.4 0.1 5.4e-14 52.0 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KIK48636.1 - 0.0023 17.4 0.0 0.003 17.0 0.0 1.4 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Glyco_hydro_47 PF01532.20 KIK48637.1 - 1.1e-111 374.0 0.0 1.6e-111 373.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 KIK48637.1 - 7.8e-07 29.0 0.0 1.7e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 PA domain Auto_anti-p27 PF06677.12 KIK48638.1 - 2.4e-24 85.2 4.6 9e-12 45.0 0.3 2.4 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Ebola_NP PF05505.12 KIK48641.1 - 0.068 11.5 4.2 0.17 10.1 4.4 1.5 1 1 1 2 2 2 0 Ebola nucleoprotein Ribonuclease_3 PF00636.26 KIK48645.1 - 4.9e-47 158.9 0.0 1.2e-22 80.5 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KIK48645.1 - 1.2e-31 109.5 0.2 9.2e-16 58.2 0.1 4.3 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KIK48645.1 - 1.5e-09 37.9 0.0 8.2e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 Dicer dimerisation domain PAZ PF02170.22 KIK48645.1 - 4e-09 36.4 0.0 8.5e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 PAZ domain COX7C PF02935.16 KIK48646.1 - 8.7e-15 54.7 1.8 9.8e-15 54.6 1.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Aldedh PF00171.22 KIK48648.1 - 6.6e-169 562.3 0.0 7.5e-169 562.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Zn_clus PF00172.18 KIK48649.1 - 1.8e-05 24.8 7.5 2.5e-05 24.3 7.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.26 KIK48651.1 - 6.8e-61 205.1 0.0 1e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIK48651.1 - 2.1e-08 33.7 0.0 7.5e-08 31.9 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature AhpC-TSA PF00578.21 KIK48652.1 - 6.7e-28 97.1 0.0 8.7e-28 96.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIK48652.1 - 8.2e-10 38.6 0.0 1.1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KIK48652.1 - 1.7e-09 37.4 0.0 2.9e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Ssu72 PF04722.13 KIK48653.1 - 3.1e-72 242.2 0.0 4e-72 241.8 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein F-box-like PF12937.7 KIK48654.1 - 2.4e-07 30.5 1.4 6.8e-07 29.1 0.5 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIK48654.1 - 0.013 15.4 0.6 0.2 11.6 0.6 2.9 1 1 0 1 1 1 0 F-box domain UreF PF01730.16 KIK48654.1 - 0.14 12.8 0.2 0.3 11.7 0.2 1.5 1 0 0 1 1 1 0 UreF N1221 PF07923.13 KIK48654.1 - 0.14 11.3 0.1 0.2 10.8 0.1 1.1 1 0 0 1 1 1 0 N1221-like protein Syntaxin-18_N PF10496.9 KIK48655.1 - 4.8e-15 55.6 3.4 9.9e-15 54.6 0.0 3.0 3 1 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 KIK48655.1 - 0.031 14.3 0.0 0.031 14.3 0.0 2.7 4 0 0 4 4 4 0 SNARE domain SNARE_assoc PF09335.11 KIK48656.1 - 5.8e-12 46.2 9.6 5.8e-12 46.2 9.6 2.8 3 1 0 3 3 3 1 SNARE associated Golgi protein DUF5489 PF17592.2 KIK48656.1 - 0.21 12.1 4.0 0.17 12.4 1.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5489) DUF3810 PF12725.7 KIK48656.1 - 0.21 10.9 3.3 0.22 10.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Tetraspanin PF00335.20 KIK48656.1 - 1.8 8.2 10.2 2 8.1 4.0 2.1 2 0 0 2 2 2 0 Tetraspanin family Fungal_trans PF04082.18 KIK48658.1 - 6.7e-21 74.5 0.0 1.2e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK48658.1 - 5.6e-05 23.2 11.4 0.0001 22.3 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DPBB_1 PF03330.18 KIK48659.1 - 1.3e-06 28.5 0.0 2.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase WD40 PF00400.32 KIK48660.1 - 1.5e-56 187.1 20.3 6.4e-07 30.0 0.2 11.8 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK48660.1 - 1.4e-25 89.4 3.9 0.0013 18.9 0.0 9.0 4 3 5 9 9 9 7 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KIK48660.1 - 6.6e-17 61.8 2.5 1.2e-16 61.0 2.5 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KIK48660.1 - 2.2e-08 33.5 6.5 0.0015 17.6 0.1 6.3 4 2 4 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK48660.1 - 2e-07 30.1 8.9 0.023 13.4 0.8 4.6 3 1 2 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KIK48660.1 - 3.3e-06 26.7 0.1 0.1 11.9 0.0 4.0 3 2 0 4 4 4 1 WD40-like domain Nucleoporin_N PF08801.11 KIK48660.1 - 4e-06 25.9 7.2 0.83 8.3 0.0 5.9 3 2 1 6 6 6 2 Nup133 N terminal like CNH PF00780.22 KIK48660.1 - 0.0014 18.3 0.2 0.42 10.2 0.0 3.1 3 0 0 3 3 3 1 CNH domain ELYS-bb PF16687.5 KIK48660.1 - 0.0088 14.7 0.0 0.2 10.2 0.0 2.5 2 0 0 2 2 2 1 beta-propeller of ELYS nucleoporin Ribosomal_L31 PF01197.18 KIK48660.1 - 0.032 14.4 0.6 2.6 8.3 0.0 2.7 2 0 0 2 2 2 0 Ribosomal protein L31 RAB3GAP2_N PF14655.6 KIK48660.1 - 0.033 13.4 1.2 0.4 9.9 0.0 3.1 3 1 1 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Frtz PF11768.8 KIK48660.1 - 0.041 12.2 0.1 6.5 4.9 0.0 3.3 2 2 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Utp21 PF04192.12 KIK48660.1 - 0.085 12.3 0.1 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 Utp21 specific WD40 associated putative domain Peptidase_M18 PF02127.15 KIK48661.1 - 3.1e-158 527.1 0.0 3.5e-158 526.9 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KIK48661.1 - 0.036 13.1 0.2 0.9 8.5 0.2 2.3 1 1 1 2 2 2 0 M42 glutamyl aminopeptidase DUF4452 PF14618.6 KIK48661.1 - 0.14 12.0 1.0 0.25 11.2 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) Piwi PF02171.17 KIK48661.1 - 0.15 11.3 0.0 0.32 10.2 0.0 1.5 1 0 0 1 1 1 0 Piwi domain Ice_nucleation PF00818.17 KIK48661.1 - 0.86 9.8 3.0 5.9 7.2 1.0 2.9 2 0 0 2 2 2 0 Ice nucleation protein repeat Brix PF04427.18 KIK48662.1 - 4e-30 105.4 0.2 5.7e-30 104.9 0.2 1.2 1 0 0 1 1 1 1 Brix domain Ribonuc_red_sm PF00268.21 KIK48663.1 - 8.7e-119 396.1 1.1 1e-118 395.8 1.1 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Ribonuc_red_sm PF00268.21 KIK48664.1 - 8.6e-122 405.9 0.7 1.1e-121 405.6 0.7 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 KIK48664.1 - 0.13 13.1 0.0 0.33 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) Alg6_Alg8 PF03155.15 KIK48665.1 - 1.1e-166 555.6 30.6 1.2e-166 555.4 30.6 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family MMR_HSR1_Xtn PF16897.5 KIK48666.1 - 2.2e-32 111.2 0.7 1.7e-31 108.4 0.3 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KIK48666.1 - 2.2e-25 88.4 0.1 3.8e-25 87.7 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KIK48666.1 - 8.1e-19 67.8 0.0 1.5e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIK48666.1 - 6.8e-09 35.4 0.1 1.4e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 KIK48666.1 - 0.014 14.4 0.2 0.028 13.4 0.2 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KIK48666.1 - 0.015 15.4 0.2 7.8 6.5 0.4 2.5 1 1 0 2 2 2 0 Dynamin family KCH PF16944.5 KIK48667.1 - 2.3e-90 302.8 17.6 2.7e-90 302.5 17.6 1.1 1 0 0 1 1 1 1 Fungal potassium channel DUF3917 PF13055.6 KIK48667.1 - 0.076 13.5 1.0 0.23 11.9 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3917) MFS_1 PF07690.16 KIK48668.1 - 1.3e-41 142.7 48.3 1.3e-41 142.7 48.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 KIK48668.1 - 0.0002 19.9 6.0 0.00039 18.9 6.0 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector Sugar_tr PF00083.24 KIK48668.1 - 0.006 15.5 36.5 0.16 10.8 35.8 3.6 1 1 0 1 1 1 1 Sugar (and other) transporter E1-E2_ATPase PF00122.20 KIK48668.1 - 1.8 8.1 5.4 0.39 10.2 0.8 2.3 2 0 0 2 2 2 0 E1-E2 ATPase BacteriocIIc_cy PF12173.8 KIK48668.1 - 2.4 8.5 7.4 3.4 8.0 0.2 3.4 3 1 0 3 3 3 0 Bacteriocin class IIc cyclic gassericin A-like MFS_1 PF07690.16 KIK48670.1 - 1.3e-35 123.0 19.8 1.6e-35 122.7 19.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1772 PF08592.11 KIK48670.1 - 0.63 10.3 3.6 1.7 9.0 0.1 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF1772) V-SNARE PF05008.15 KIK48671.1 - 1.8e-20 73.1 1.3 1.8e-20 73.1 1.3 2.4 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KIK48671.1 - 2.1e-16 60.0 8.9 3e-16 59.5 5.7 2.5 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KIK48671.1 - 0.0005 19.9 0.6 0.0005 19.9 0.6 1.7 2 0 0 2 2 2 1 Sec20 SNARE PF05739.19 KIK48671.1 - 0.039 14.0 1.5 0.039 14.0 1.5 2.4 3 0 0 3 3 3 0 SNARE domain DUF3671 PF12420.8 KIK48671.1 - 0.051 13.7 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF241 PF03087.14 KIK48671.1 - 0.071 12.9 1.6 0.32 10.8 0.1 2.2 2 0 0 2 2 2 0 Arabidopsis protein of unknown function CC2-LZ PF16516.5 KIK48671.1 - 3.2 8.2 7.9 4.5 7.7 0.3 2.8 3 1 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Lebercilin PF15619.6 KIK48671.1 - 4.9 6.8 11.3 1.8 8.2 2.9 2.3 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease EMC3_TMCO1 PF01956.16 KIK48672.1 - 1.3e-52 177.9 0.1 1.6e-52 177.6 0.1 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like EF-hand_7 PF13499.6 KIK48673.1 - 1.3e-26 92.9 7.2 2.3e-17 63.2 1.5 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KIK48673.1 - 4.6e-25 85.3 12.1 2.7e-08 32.8 0.1 5.2 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KIK48673.1 - 2.6e-21 73.6 8.9 1.6e-06 27.5 0.1 5.2 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 KIK48673.1 - 1.2e-12 47.5 10.5 2e-05 24.3 1.1 3.8 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KIK48673.1 - 1.3e-12 46.6 9.3 0.00077 18.8 0.4 4.5 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 KIK48673.1 - 1.4e-06 28.2 5.6 0.12 12.3 0.1 4.0 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KIK48673.1 - 8.9e-05 22.8 2.9 0.13 12.6 0.4 3.6 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KIK48673.1 - 0.002 18.4 2.9 2.2 8.7 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain Pan3_PK PF18101.1 KIK48673.1 - 0.067 13.2 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Pan3 Pseudokinase domain Caleosin PF05042.13 KIK48673.1 - 0.076 12.9 2.9 8.8 6.2 0.0 3.2 2 1 1 3 3 3 0 Caleosin related protein EF-hand_2 PF09068.11 KIK48673.1 - 0.15 12.2 0.0 5.4 7.2 0.0 2.6 3 0 0 3 3 3 0 EF hand WD40 PF00400.32 KIK48675.1 - 0.00065 20.5 0.1 0.4 11.6 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK48675.1 - 0.0015 18.8 0.0 0.32 11.3 0.0 2.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF839 PF05787.13 KIK48675.1 - 0.048 12.8 0.0 0.073 12.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) DUF1513 PF07433.11 KIK48675.1 - 0.091 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) ATE_C PF04377.15 KIK48676.1 - 9.2e-44 149.3 0.2 1.7e-43 148.5 0.2 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KIK48676.1 - 1.3e-25 89.6 3.3 2.3e-25 88.8 3.3 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Peptidase_S24 PF00717.23 KIK48677.1 - 2.2e-05 24.3 0.3 3.6e-05 23.6 0.3 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KIK48677.1 - 0.0015 18.3 0.0 1.4 8.7 0.0 2.4 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 SMC_N PF02463.19 KIK48679.1 - 1.1e-27 96.9 3.5 3.7e-27 95.2 3.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIK48679.1 - 6.7e-13 49.6 17.8 1.5e-10 41.9 17.8 2.2 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KIK48679.1 - 4.8e-09 36.4 1.7 1.1e-08 35.3 1.7 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KIK48679.1 - 8.4e-09 35.6 0.3 2.4e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIK48679.1 - 7.9e-08 31.9 0.0 1.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DHR10 PF18595.1 KIK48679.1 - 0.00015 21.8 14.1 0.00015 21.8 14.1 2.4 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain DUF2813 PF11398.8 KIK48679.1 - 0.0066 15.8 0.0 0.0066 15.8 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2813) ABC_tran PF00005.27 KIK48679.1 - 0.019 15.5 5.0 0.43 11.1 5.0 2.6 1 1 0 1 1 1 0 ABC transporter AAA_27 PF13514.6 KIK48679.1 - 0.031 13.9 4.6 0.06 12.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain CENP-H PF05837.12 KIK48679.1 - 6 7.3 18.7 4.3 7.8 10.3 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) SMC_hinge PF06470.13 KIK48680.1 - 1.9e-12 47.5 0.0 3.6e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain APG6_N PF17675.1 KIK48680.1 - 0.012 16.2 3.0 0.016 15.7 3.0 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region JIP_LZII PF16471.5 KIK48680.1 - 0.024 14.8 1.5 0.094 12.9 1.5 1.9 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II Phe_tRNA-synt_N PF02912.18 KIK48680.1 - 0.031 14.2 0.2 0.067 13.1 0.2 1.5 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain PEP-utilisers_N PF05524.13 KIK48680.1 - 0.041 14.1 0.2 0.1 12.8 0.2 1.7 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Laminin_II PF06009.12 KIK48680.1 - 0.045 13.8 2.5 0.74 9.8 0.5 2.2 1 1 1 2 2 2 0 Laminin Domain II Filo_VP35 PF02097.15 KIK48680.1 - 0.048 12.7 0.1 0.06 12.4 0.1 1.1 1 0 0 1 1 1 0 Filoviridae VP35 Seryl_tRNA_N PF02403.22 KIK48680.1 - 0.072 13.3 2.6 0.16 12.2 2.6 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4201 PF13870.6 KIK48680.1 - 0.09 12.5 2.7 0.17 11.6 2.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) FliJ PF02050.16 KIK48680.1 - 0.091 13.0 0.9 0.14 12.4 0.9 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein Spc7 PF08317.11 KIK48680.1 - 0.093 11.6 4.3 0.12 11.2 4.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein SlyX PF04102.12 KIK48680.1 - 0.16 12.6 1.3 3.7 8.2 0.1 2.3 1 1 1 2 2 2 0 SlyX YabA PF06156.13 KIK48680.1 - 0.23 12.1 1.2 0.28 11.8 0.4 1.5 2 0 0 2 2 1 0 Initiation control protein YabA Prefoldin_2 PF01920.20 KIK48680.1 - 0.28 11.2 2.5 0.46 10.5 0.7 2.1 1 1 1 2 2 2 0 Prefoldin subunit CCDC-167 PF15188.6 KIK48680.1 - 2.4 8.5 6.7 1.2 9.5 3.0 2.3 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 SMC_N PF02463.19 KIK48681.1 - 2.6e-06 27.0 0.0 3.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain OmpH PF03938.14 KIK48681.1 - 0.0015 18.9 2.1 0.002 18.4 2.1 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) LemA PF04011.12 KIK48681.1 - 0.0024 17.7 0.4 0.0037 17.1 0.4 1.3 1 0 0 1 1 1 1 LemA family XhlA PF10779.9 KIK48681.1 - 0.005 17.0 5.3 1.6 9.0 0.0 2.3 1 1 1 2 2 2 2 Haemolysin XhlA GAS PF13851.6 KIK48681.1 - 0.0067 15.8 1.9 0.0097 15.3 1.9 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 KIK48681.1 - 0.0089 16.0 1.6 0.013 15.5 1.6 1.2 1 0 0 1 1 1 1 Laminin Domain II AAA_13 PF13166.6 KIK48681.1 - 0.0092 14.7 0.4 0.011 14.4 0.4 1.1 1 0 0 1 1 1 1 AAA domain APG6_N PF17675.1 KIK48681.1 - 0.016 15.7 4.9 0.024 15.1 4.9 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region IFT57 PF10498.9 KIK48681.1 - 0.023 13.7 4.8 0.028 13.4 4.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 RPW8 PF05659.11 KIK48681.1 - 0.026 14.2 0.1 0.07 12.8 0.1 1.5 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Cytochrom_B562 PF07361.11 KIK48681.1 - 0.026 15.1 1.7 0.053 14.2 1.5 1.5 1 1 0 1 1 1 0 Cytochrome b562 DUF724 PF05266.14 KIK48681.1 - 0.077 12.8 2.9 0.12 12.2 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Muted PF14942.6 KIK48681.1 - 0.078 13.3 3.5 0.12 12.7 3.5 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Glutaredoxin2_C PF04399.13 KIK48681.1 - 0.082 12.7 0.3 4.1 7.3 0.0 2.2 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain DUF5082 PF16888.5 KIK48681.1 - 0.094 13.0 2.4 0.14 12.4 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) SbcCD_C PF13558.6 KIK48681.1 - 0.094 13.0 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ATF7IP_BD PF16788.5 KIK48681.1 - 0.1 12.7 2.3 0.15 12.2 2.3 1.2 1 0 0 1 1 1 0 ATF-interacting protein binding domain SOAR PF16533.5 KIK48681.1 - 0.13 12.2 2.1 0.35 10.9 1.4 1.9 1 1 1 2 2 2 0 STIM1 Orai1-activating region DUF1664 PF07889.12 KIK48681.1 - 0.27 11.3 0.8 9 6.4 0.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KIK48681.1 - 0.37 10.1 4.1 0.53 9.6 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4337 PF14235.6 KIK48681.1 - 0.82 9.8 4.0 1.7 8.7 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Sec63 PF02889.16 KIK48683.1 - 1.7e-74 250.3 0.0 2.5e-74 249.7 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KIK48683.1 - 1.1e-37 129.5 2.3 1.1e-26 93.7 0.3 3.6 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 KIK48683.1 - 2.9e-17 63.2 0.0 4.1e-11 43.2 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIK48683.1 - 2.5e-09 37.4 0.0 4.1e-05 23.9 0.0 4.3 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KIK48683.1 - 0.00018 21.8 0.2 0.0082 16.4 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KIK48683.1 - 0.012 16.0 0.2 0.046 14.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KIK48683.1 - 0.014 14.5 0.0 1.8 7.6 0.0 2.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_11 PF13086.6 KIK48683.1 - 0.021 14.6 0.5 0.22 11.3 0.1 2.7 3 1 0 3 3 3 0 AAA domain Phage_TAC_7 PF10109.9 KIK48683.1 - 0.03 14.4 0.4 0.56 10.3 0.1 2.8 3 0 0 3 3 3 0 Phage tail assembly chaperone proteins, E, or 41 or 14 UvrD-helicase PF00580.21 KIK48683.1 - 0.16 11.4 0.1 0.28 10.7 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Aminotran_1_2 PF00155.21 KIK48684.1 - 9.6e-63 212.5 0.0 1.1e-62 212.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIK48684.1 - 7e-05 21.5 0.0 0.00011 20.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KIK48684.1 - 0.00012 21.5 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KIK48684.1 - 0.0059 15.9 0.0 0.0081 15.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KIK48684.1 - 0.0067 15.4 0.0 0.035 13.1 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V FYVE PF01363.21 KIK48685.1 - 6.9e-19 67.8 8.9 6.9e-19 67.8 8.9 2.5 3 0 0 3 3 3 1 FYVE zinc finger Ank_5 PF13857.6 KIK48685.1 - 3.6e-05 24.0 0.0 7.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-RING_11 PF17123.5 KIK48685.1 - 0.015 15.0 2.9 0.015 15.0 2.9 2.3 2 0 0 2 2 2 0 RING-like zinc finger DUF5308 PF17233.2 KIK48685.1 - 0.064 13.5 1.2 0.17 12.1 0.6 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5308) zf-RING_2 PF13639.6 KIK48685.1 - 0.17 12.3 16.5 0.083 13.2 1.2 3.6 3 0 0 3 3 3 0 Ring finger domain PI31_Prot_N PF11566.8 KIK48687.1 - 5e-43 146.7 0.0 6.1e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KIK48687.1 - 3.2e-13 50.6 18.3 3.2e-13 50.6 18.3 3.0 2 1 1 3 3 3 1 PI31 proteasome regulator MMgT PF10270.9 KIK48687.1 - 0.14 12.6 0.0 0.23 11.8 0.0 1.2 1 0 0 1 1 1 0 Membrane magnesium transporter DEAD PF00270.29 KIK48688.1 - 1.8e-51 174.4 0.0 1.2e-50 171.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK48688.1 - 5.9e-26 91.0 0.0 2.4e-25 89.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK48688.1 - 0.00075 19.5 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NuDC PF16273.5 KIK48688.1 - 0.34 11.5 0.0 0.34 11.5 0.0 5.3 6 0 0 6 6 6 0 Nuclear distribution C domain Nup88 PF10168.9 KIK48689.1 - 2.7e-22 78.4 3.1 5.3e-13 47.7 0.0 3.1 2 1 0 2 2 2 2 Nuclear pore component Nup54 PF13874.6 KIK48689.1 - 0.014 15.5 12.8 0.096 12.8 12.8 2.1 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Syntaxin_2 PF14523.6 KIK48689.1 - 0.16 12.3 0.4 2.6 8.5 0.1 2.4 2 0 0 2 2 2 0 Syntaxin-like protein Spectrin PF00435.21 KIK48689.1 - 0.21 12.1 4.4 0.3 11.6 1.6 2.4 2 1 0 2 2 2 0 Spectrin repeat Nbl1_Borealin_N PF10444.9 KIK48689.1 - 0.48 10.1 3.9 0.29 10.8 0.8 2.3 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal ABC_tran_Xtn PF12848.7 KIK48689.1 - 1.1 9.4 8.4 0.11 12.5 3.1 2.0 2 0 0 2 2 2 0 ABC transporter Exonuc_VII_L PF02601.15 KIK48689.1 - 1.1 8.8 4.1 1.7 8.1 4.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Proteasome PF00227.26 KIK48690.1 - 1.6e-45 155.0 0.0 2.1e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIK48690.1 - 1.9e-13 49.8 0.1 3.3e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CSN8_PSD8_EIF3K PF10075.9 KIK48691.1 - 3.4e-29 101.7 0.0 5.5e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KIK48691.1 - 0.00023 20.7 0.0 0.00031 20.3 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP family Proteasome PF00227.26 KIK48692.1 - 1.9e-42 144.9 0.1 2.2e-42 144.7 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit GFO_IDH_MocA PF01408.22 KIK48695.1 - 7.9e-20 71.9 0.1 1.4e-19 71.1 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIK48695.1 - 8.4e-05 22.6 0.0 0.00097 19.1 0.0 2.5 3 0 0 3 3 3 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.17 KIK48695.1 - 0.09 13.4 0.0 0.2 12.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KIK48695.1 - 0.11 12.7 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Abhydrolase_6 PF12697.7 KIK48696.1 - 2.8e-09 37.9 0.5 3.8e-09 37.5 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family FliG_C PF01706.16 KIK48696.1 - 0.049 13.8 0.1 0.088 13.0 0.1 1.3 1 0 0 1 1 1 0 FliG C-terminal domain CDT1_C PF16679.5 KIK48697.1 - 2.3e-13 50.4 0.1 7.7e-13 48.7 0.1 1.9 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain zf-CCCH PF00642.24 KIK48699.1 - 0.00061 19.6 19.1 0.054 13.4 2.3 3.9 2 1 2 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KIK48699.1 - 0.00072 19.3 1.2 0.00072 19.3 1.2 3.8 2 1 1 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KIK48699.1 - 0.015 15.4 23.0 0.16 12.1 2.8 4.4 4 0 0 4 4 4 0 Zinc finger domain Omp28 PF11551.8 KIK48699.1 - 0.24 11.2 0.0 0.4 10.5 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein Omp28 zf-CCCH_2 PF14608.6 KIK48699.1 - 0.84 10.2 13.4 0.89 10.1 0.2 3.5 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KIK48699.1 - 2.9 8.6 10.2 7.7 7.3 0.9 2.6 1 1 1 2 2 2 0 Torus domain zf-CCCH_3 PF15663.5 KIK48699.1 - 8.3 6.7 9.4 3.7 7.8 1.4 2.3 1 1 0 2 2 2 0 Zinc-finger containing family zf-CCCH PF00642.24 KIK48700.1 - 3.2 7.8 24.9 0.32 10.9 1.3 4.8 4 1 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Rho_GDI PF02115.17 KIK48701.1 - 1.7e-54 184.6 0.0 1.9e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor PBP_dimer PF03717.15 KIK48701.1 - 0.12 12.7 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain UbiA PF01040.18 KIK48702.1 - 1.3e-49 168.7 17.5 1.7e-49 168.4 17.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family RNA_pol_Rpb8 PF03870.15 KIK48703.1 - 8.1e-33 113.5 0.0 9.1e-33 113.4 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Ytp1 PF10355.9 KIK48704.1 - 2e-107 358.5 6.5 2e-107 358.5 6.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KIK48704.1 - 5e-14 52.0 6.4 5e-14 52.0 6.4 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Frag1 PF10277.9 KIK48704.1 - 0.011 15.3 16.3 0.03 13.8 2.7 2.9 3 0 0 3 3 3 0 Frag1/DRAM/Sfk1 family MFS_1 PF07690.16 KIK48707.1 - 8.6e-20 71.0 9.4 8.5e-19 67.7 11.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily EphA2_TM PF14575.6 KIK48708.1 - 0.048 14.6 0.0 0.087 13.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FeoB_associated PF12669.7 KIK48708.1 - 0.12 12.8 1.6 0.2 12.1 1.6 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein RIFIN PF02009.16 KIK48708.1 - 0.23 11.3 0.0 0.29 11.0 0.0 1.1 1 0 0 1 1 1 0 Rifin cNMP_binding PF00027.29 KIK48709.1 - 4.7e-32 109.9 0.9 1.3e-14 54.0 0.1 3.3 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 KIK48709.1 - 1.2e-12 47.3 0.1 3.1e-12 45.9 0.1 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF2672 PF10878.8 KIK48709.1 - 0.049 13.6 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2672) Pkinase PF00069.25 KIK48710.1 - 6.4e-76 255.2 0.0 9.1e-76 254.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK48710.1 - 1.4e-35 122.8 0.0 2.9e-35 121.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK48710.1 - 0.00021 20.4 0.0 0.0016 17.5 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Med15 PF09606.10 KIK48710.1 - 0.1 11.3 39.8 0.14 10.8 39.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Kinase-like PF14531.6 KIK48710.1 - 0.11 11.8 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KIK48710.1 - 0.26 11.2 0.0 0.26 11.2 0.0 2.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF737 PF05300.11 KIK48710.1 - 3.6 7.9 9.6 5.4 7.3 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) TFIIA PF03153.13 KIK48710.1 - 5.9 6.8 27.3 7.8 6.4 27.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Utp12 PF04003.12 KIK48711.1 - 6.1e-27 94.0 0.0 8.9e-27 93.5 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family UTP15_C PF09384.10 KIK48711.1 - 0.029 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 UTP15 C terminal BUD22 PF09073.10 KIK48711.1 - 8.8 5.5 23.5 2.4 7.4 10.4 2.1 2 0 0 2 2 2 0 BUD22 ubiquitin PF00240.23 KIK48712.1 - 1.6e-05 24.6 0.0 2.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KIK48712.1 - 0.18 12.4 0.1 0.55 10.8 0.0 1.8 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain DUF4633 PF15464.6 KIK48712.1 - 0.22 11.7 4.1 0.58 10.3 3.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) Pkinase PF00069.25 KIK48714.1 - 1.3e-50 172.2 0.0 1.5e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK48714.1 - 8.2e-36 123.6 0.0 1.1e-35 123.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK48714.1 - 2.3e-05 23.9 0.0 8.2e-05 22.1 0.0 1.7 1 1 0 2 2 2 1 Kinase-like GFO_IDH_MocA PF01408.22 KIK48715.1 - 1.5e-23 83.9 0.0 2.7e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIK48715.1 - 7e-07 29.3 0.0 1.4e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Glyco_hydro_9 PF00759.19 KIK48716.1 - 3.7e-109 365.9 13.8 4.4e-109 365.6 13.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Leader_Trp PF08255.11 KIK48716.1 - 0.051 13.5 1.8 0.16 12.0 1.8 1.9 1 0 0 1 1 1 0 Trp-operon Leader Peptide FAD_binding_1 PF00667.20 KIK48718.1 - 5.7e-53 179.8 0.0 8.4e-53 179.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KIK48718.1 - 1.1e-07 32.5 0.0 2.4e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KIK48718.1 - 0.011 16.1 0.0 0.046 14.1 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain POR_N PF01855.19 KIK48718.1 - 0.027 14.2 0.6 0.078 12.7 0.2 1.9 2 0 0 2 2 2 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DUF2685 PF10886.8 KIK48718.1 - 0.19 11.9 0.0 0.44 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2685) UPRTase PF14681.6 KIK48719.1 - 9.6e-68 227.7 0.0 1.1e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KIK48719.1 - 0.21 11.1 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Methyltransf_8 PF05148.15 KIK48720.1 - 1.8e-67 227.4 0.0 3.9e-67 226.3 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KIK48720.1 - 1.9e-06 28.4 0.0 9.5e-06 26.2 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK48720.1 - 1.6e-05 25.5 0.0 5.2e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK48720.1 - 0.00045 20.0 0.0 0.0027 17.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK48720.1 - 0.002 18.8 0.0 0.011 16.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK48720.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KIK48720.1 - 0.032 13.6 0.0 0.21 10.9 0.0 2.1 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family AAA_22 PF13401.6 KIK48722.1 - 0.00012 22.4 0.2 0.46 10.7 0.0 2.5 2 1 0 2 2 2 2 AAA domain Zot PF05707.12 KIK48722.1 - 0.0052 16.4 0.0 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA PF00004.29 KIK48722.1 - 0.012 16.1 0.0 0.45 11.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK48722.1 - 0.013 15.9 0.2 3 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 KIK48722.1 - 0.05 13.7 0.2 0.13 12.3 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain Zeta_toxin PF06414.12 KIK48722.1 - 0.15 11.3 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Pkinase PF00069.25 KIK48723.1 - 8.3e-49 166.3 0.0 1.1e-48 165.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK48723.1 - 1.9e-17 63.4 0.0 2.9e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK48723.1 - 0.0028 17.0 0.8 1.3 8.3 0.1 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KIK48723.1 - 0.04 12.7 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SPATA3 PF15662.5 KIK48724.1 - 0.018 15.7 13.7 0.023 15.3 13.7 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Pkinase PF00069.25 KIK48724.1 - 0.041 13.2 0.0 0.041 13.2 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain Band_3_cyto PF07565.13 KIK48724.1 - 0.088 12.6 9.5 0.11 12.2 9.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MCM_bind PF09739.9 KIK48724.1 - 0.091 11.2 11.5 0.11 10.9 11.5 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Presenilin PF01080.17 KIK48724.1 - 0.13 11.0 12.7 0.13 11.0 12.7 1.0 1 0 0 1 1 1 0 Presenilin Baculo_PP31 PF05311.11 KIK48724.1 - 0.14 11.6 9.3 0.18 11.2 9.3 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) TFIIA PF03153.13 KIK48724.1 - 0.16 12.0 21.8 0.17 11.8 21.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KIK48724.1 - 0.41 10.2 24.6 0.58 9.7 24.6 1.3 1 0 0 1 1 1 0 Spt20 family PAT1 PF09770.9 KIK48724.1 - 0.43 8.8 20.4 0.47 8.6 20.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.22 KIK48724.1 - 0.48 9.6 11.0 0.51 9.5 11.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Plasmodium_Vir PF05795.11 KIK48724.1 - 0.5 9.7 7.4 0.54 9.6 7.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Sec62 PF03839.16 KIK48724.1 - 0.51 9.8 6.5 0.59 9.6 6.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 SLC12 PF03522.15 KIK48724.1 - 0.69 8.9 10.2 0.72 8.8 10.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 TERB2 PF15101.6 KIK48724.1 - 1 9.4 10.3 1.2 9.1 10.3 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 RR_TM4-6 PF06459.12 KIK48724.1 - 1.4 8.7 14.7 1.6 8.5 14.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 U79_P34 PF03064.16 KIK48724.1 - 1.6 8.1 10.0 1.9 7.8 10.0 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NPR3 PF03666.13 KIK48724.1 - 1.7 7.3 14.2 2.1 7.0 14.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 KIK48724.1 - 1.9 7.4 6.9 2.1 7.3 6.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NARP1 PF12569.8 KIK48724.1 - 2 7.2 11.0 2.1 7.2 11.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TMEM51 PF15345.6 KIK48724.1 - 2 8.2 10.9 2.9 7.7 10.9 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 MDM10 PF12519.8 KIK48724.1 - 2.4 7.0 9.1 2.8 6.7 9.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Suf PF05843.14 KIK48724.1 - 2.5 8.0 13.6 2.6 8.0 13.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CPSF100_C PF13299.6 KIK48724.1 - 2.8 8.1 9.2 3.7 7.7 9.2 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Membralin PF09746.9 KIK48724.1 - 4.8 6.1 4.5 5 6.1 4.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein Tim54 PF11711.8 KIK48724.1 - 5.3 5.7 14.0 6.2 5.5 14.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Neur_chan_memb PF02932.16 KIK48724.1 - 5.3 7.0 9.9 6.3 6.8 9.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.10 KIK48724.1 - 5.5 5.5 10.2 5.7 5.5 10.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDC45 PF02724.14 KIK48724.1 - 5.8 5.1 11.1 6.1 5.0 11.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4407 PF14362.6 KIK48724.1 - 7.6 5.8 9.0 9.2 5.5 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ALMT PF11744.8 KIK48724.1 - 8.1 5.1 8.6 9.6 4.9 8.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Paramyxo_ncap PF00973.19 KIK48724.1 - 9.1 5.1 8.1 10 4.9 8.1 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Mg_trans_NIPA PF05653.14 KIK48725.1 - 9.1e-60 202.2 11.8 1.7e-56 191.5 7.3 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KIK48725.1 - 0.0003 21.0 1.2 0.0003 21.0 1.2 3.8 3 1 0 3 3 3 1 EamA-like transporter family PHO4 PF01384.20 KIK48725.1 - 2.6 7.0 9.5 15 4.5 9.6 2.0 1 1 0 1 1 1 0 Phosphate transporter family WD40 PF00400.32 KIK48726.1 - 3e-12 46.8 1.7 7.6e-06 26.6 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK48726.1 - 0.00038 20.7 0.0 1.5 9.2 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIK48726.1 - 0.0035 17.2 0.0 5.9 6.9 0.0 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat TFIID-31kDa PF02291.15 KIK48727.1 - 5.1e-37 126.7 0.0 7.2e-37 126.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 KIK48727.1 - 0.00028 21.2 0.0 0.00057 20.2 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.13 KIK48727.1 - 0.0008 19.4 0.0 0.0021 18.0 0.0 1.7 2 0 0 2 2 2 1 Bromodomain associated CENP-T_C PF15511.6 KIK48727.1 - 0.00088 19.4 0.0 0.0019 18.3 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KIK48727.1 - 0.021 15.2 0.0 0.032 14.6 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 SDA1 PF05285.12 KIK48727.1 - 0.054 12.9 3.1 0.076 12.4 3.1 1.3 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 KIK48727.1 - 2.6 7.9 8.6 0.78 9.6 0.4 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region BUD22 PF09073.10 KIK48727.1 - 4.6 6.5 11.4 6 6.1 11.4 1.1 1 0 0 1 1 1 0 BUD22 DUF3246 PF11596.8 KIK48727.1 - 5.5 6.3 13.9 9.5 5.6 13.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) NifU_N PF01592.16 KIK48728.1 - 6.2e-53 178.3 0.0 9.7e-53 177.7 0.0 1.3 1 0 0 1 1 1 1 NifU-like N terminal domain Nop PF01798.18 KIK48729.1 - 5.1e-72 242.1 0.0 7.1e-72 241.6 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KIK48729.1 - 5.6e-39 133.8 5.5 1.2e-38 132.8 5.5 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain IF-2B PF01008.17 KIK48729.1 - 0.019 14.2 0.1 0.45 9.7 0.0 2.7 2 1 0 2 2 2 0 Initiation factor 2 subunit family CobD_Cbib PF03186.13 KIK48729.1 - 0.037 13.2 0.1 0.061 12.5 0.1 1.3 1 0 0 1 1 1 0 CobD/Cbib protein Latarcin PF10279.9 KIK48729.1 - 0.99 9.9 0.0 0.99 9.9 0.0 3.3 4 0 0 4 4 4 0 Latarcin precursor F-box-like PF12937.7 KIK48730.1 - 0.00074 19.4 1.2 0.0023 17.8 0.1 2.5 3 0 0 3 3 3 1 F-box-like Med10 PF09748.9 KIK48731.1 - 2.9e-18 66.0 0.0 3.5e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex PIN_4 PF13638.6 KIK48731.1 - 0.0078 16.5 0.1 0.0099 16.2 0.1 1.2 1 0 0 1 1 1 1 PIN domain ApoL PF05461.11 KIK48731.1 - 0.061 12.6 0.0 0.079 12.3 0.0 1.0 1 0 0 1 1 1 0 Apolipoprotein L DUF2009 PF09418.10 KIK48731.1 - 0.14 11.2 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Tctex-1 PF03645.13 KIK48735.1 - 7.7e-11 42.1 0.0 8.8e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family PEX11 PF05648.14 KIK48736.1 - 5e-14 52.3 3.0 1.7e-07 31.0 0.3 2.2 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) TMF_DNA_bd PF12329.8 KIK48737.1 - 0.05 13.6 0.4 0.067 13.2 0.4 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Laminin_II PF06009.12 KIK48737.1 - 0.062 13.3 0.1 0.081 12.9 0.1 1.1 1 0 0 1 1 1 0 Laminin Domain II DUF948 PF06103.11 KIK48737.1 - 0.14 12.4 0.0 0.19 12.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SNARE_assoc PF09335.11 KIK48738.1 - 1e-13 51.8 7.0 1e-13 51.8 7.0 2.2 2 1 2 4 4 4 1 SNARE associated Golgi protein DUF5056 PF16479.5 KIK48738.1 - 0.14 12.4 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5056) HSF_DNA-bind PF00447.17 KIK48739.1 - 4e-18 65.8 0.0 6.6e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Pkinase PF00069.25 KIK48740.1 - 2.9e-71 239.9 0.0 3.7e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK48740.1 - 2.5e-28 99.1 0.0 9.6e-21 74.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIK48740.1 - 6.9e-09 35.4 0.1 0.038 13.3 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 KIK48740.1 - 0.00041 19.3 0.7 0.0021 16.9 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase MFS_1 PF07690.16 KIK48741.1 - 1.3e-46 159.1 60.6 1e-40 139.8 40.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK48741.1 - 1.5e-11 43.9 4.2 1.5e-11 43.9 4.2 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KIK48741.1 - 2e-06 26.5 13.4 3.2e-06 25.9 8.2 2.3 1 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) COA2 PF17051.5 KIK48742.1 - 6.7e-06 26.1 0.0 8.2e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 COX14 PF14880.6 KIK48742.1 - 0.067 13.0 1.2 0.11 12.3 1.2 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Ribosomal_S14 PF00253.21 KIK48743.1 - 5.2e-20 71.0 0.3 7.8e-20 70.4 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF3425 PF11905.8 KIK48744.1 - 1.5e-15 57.3 3.7 7e-15 55.1 0.5 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KIK48744.1 - 7e-08 32.5 4.0 1.4e-07 31.5 4.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIK48744.1 - 0.004 17.2 4.0 0.004 17.2 4.0 2.0 2 0 0 2 2 2 1 Basic region leucine zipper Mto2_bdg PF12808.7 KIK48744.1 - 0.092 13.1 2.9 0.22 11.8 2.9 1.7 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DNA_RNApol_7kD PF03604.13 KIK48747.1 - 8.8e-18 63.7 8.4 1.1e-17 63.4 8.4 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_10 PF10058.9 KIK48747.1 - 0.001 18.7 0.2 0.078 12.7 0.0 2.1 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein DZR PF12773.7 KIK48747.1 - 0.0027 17.7 0.4 0.0035 17.3 0.4 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 KIK48747.1 - 0.0044 17.0 0.3 0.0045 17.0 0.3 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 KIK48747.1 - 0.0048 17.0 2.8 0.01 15.9 2.8 1.6 1 1 0 1 1 1 1 Zinc ribbon domain zf-ISL3 PF14690.6 KIK48747.1 - 0.01 16.5 1.9 0.055 14.1 0.3 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_2 PF13240.6 KIK48747.1 - 0.01 15.5 1.7 0.029 14.1 1.7 1.7 1 1 0 1 1 1 0 zinc-ribbon domain zf-C3HC PF07967.13 KIK48747.1 - 0.01 15.8 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 0 C3HC zinc finger-like Zn_ribbon_recom PF13408.6 KIK48747.1 - 0.012 16.1 3.2 0.27 11.8 0.5 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain MCM_OB PF17207.3 KIK48747.1 - 0.013 15.3 0.4 0.015 15.2 0.4 1.1 1 0 0 1 1 1 0 MCM OB domain OrfB_Zn_ribbon PF07282.11 KIK48747.1 - 0.019 14.9 0.9 0.025 14.5 0.9 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-trcl PF13451.6 KIK48747.1 - 0.02 14.7 5.7 0.37 10.7 0.2 2.2 1 1 1 2 2 2 0 Probable zinc-ribbon domain zinc-ribbon_6 PF10005.9 KIK48747.1 - 0.023 15.4 0.2 0.031 15.0 0.2 1.2 1 0 0 1 1 1 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KIK48747.1 - 0.031 13.8 2.5 0.44 10.1 0.1 2.2 1 1 1 2 2 2 0 TFIIB zinc-binding DUF35_N PF12172.8 KIK48747.1 - 0.12 12.3 1.7 1.9 8.4 0.1 2.4 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-ribbon_3 PF13248.6 KIK48747.1 - 0.12 11.8 2.6 0.71 9.4 2.6 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 KIK48747.1 - 0.12 12.1 4.0 5.3 6.9 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-Sec23_Sec24 PF04810.15 KIK48747.1 - 0.12 12.4 3.1 8.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf_UBZ PF18439.1 KIK48747.1 - 0.16 11.6 2.3 6.3 6.5 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-NADH-PPase PF09297.11 KIK48747.1 - 0.17 11.5 3.4 0.6 9.8 3.4 1.9 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain QWRF PF04484.12 KIK48748.1 - 6.7 6.4 11.9 8.4 6.0 11.9 1.1 1 0 0 1 1 1 0 QWRF family DUF4187 PF13821.6 KIK48749.1 - 8.8e-21 73.4 0.9 1.8e-20 72.5 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Nop53 PF07767.11 KIK48749.1 - 0.012 15.1 5.7 0.012 15.1 5.7 1.9 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) G-patch PF01585.23 KIK48749.1 - 0.043 13.7 2.2 0.043 13.7 2.2 2.1 2 0 0 2 2 2 0 G-patch domain RRM_1 PF00076.22 KIK48750.1 - 2.6e-27 94.4 0.0 2.1e-13 49.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIK48750.1 - 0.014 15.0 0.0 0.24 11.0 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4944 PF16302.5 KIK48750.1 - 0.023 14.7 0.2 0.92 9.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4944) Totivirus_coat PF05518.11 KIK48750.1 - 0.045 11.8 6.6 0.056 11.5 6.6 1.1 1 0 0 1 1 1 0 Totivirus coat protein OB_RNB PF08206.11 KIK48750.1 - 0.14 11.9 3.3 23 4.8 1.4 3.3 2 1 0 2 2 2 0 Ribonuclease B OB domain Limkain-b1 PF11608.8 KIK48750.1 - 0.16 12.0 0.5 0.99 9.5 0.1 2.4 3 0 0 3 3 3 0 Limkain b1 LYRIC PF15686.5 KIK48750.1 - 0.74 9.3 11.4 1.1 8.8 11.4 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family PGA2 PF07543.12 KIK48750.1 - 1.7 8.6 8.6 3.2 7.7 8.6 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Glyco_hydro_cc PF11790.8 KIK48751.1 - 5.6e-57 193.0 3.3 8.1e-57 192.5 3.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Speriolin_C PF15059.6 KIK48752.1 - 0.046 13.8 0.0 1 9.5 0.0 2.3 2 0 0 2 2 2 0 Speriolin C-terminus Ribosomal_L11 PF00298.19 KIK48755.1 - 3.6e-28 97.9 0.7 5.2e-28 97.3 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KIK48755.1 - 1.2e-25 89.1 0.2 2.2e-25 88.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain WD40 PF00400.32 KIK48757.1 - 0.27 12.2 2.8 2.1 9.4 0.0 3.2 4 0 0 4 4 4 0 WD domain, G-beta repeat WD40 PF00400.32 KIK48758.1 - 1e-06 29.3 3.8 1.2 10.1 0.2 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat PALB2_WD40 PF16756.5 KIK48758.1 - 0.013 14.4 0.0 0.12 11.3 0.0 2.0 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Lgl_C PF08596.10 KIK48758.1 - 0.1 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal Hfq PF17209.3 KIK48759.1 - 0.015 15.0 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Hfq protein NUFIP1 PF10453.9 KIK48759.1 - 0.016 15.0 0.3 0.03 14.2 0.3 1.5 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) C2 PF00168.30 KIK48760.1 - 2.7e-15 56.5 0.0 3.4e-11 43.4 0.0 2.3 2 0 0 2 2 2 2 C2 domain HnRNP_M PF11532.8 KIK48760.1 - 0.69 10.2 6.0 0.19 12.0 1.0 2.4 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein M Glyco_hydro_125 PF06824.11 KIK48761.1 - 8.3e-149 496.0 0.0 9.6e-149 495.8 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) zf-piccolo PF05715.13 KIK48761.1 - 0.12 12.5 0.1 0.31 11.2 0.1 1.8 1 1 0 1 1 1 0 Piccolo Zn-finger Aconitase PF00330.20 KIK48763.1 - 2.4e-160 534.6 0.0 2.9e-160 534.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KIK48763.1 - 5.3e-40 136.8 0.0 9e-40 136.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Tau95 PF09734.9 KIK48764.1 - 2.1e-37 129.0 4.0 2.5e-37 128.8 0.4 2.5 3 0 0 3 3 3 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KIK48764.1 - 2.6e-25 89.1 0.0 1.1e-24 87.0 0.0 2.1 1 1 0 1 1 1 1 Tau95 Triple barrel domain REF PF05755.12 KIK48765.1 - 0.017 15.0 0.0 0.022 14.6 0.0 1.1 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) PPR_long PF17177.4 KIK48765.1 - 0.048 13.0 0.2 0.069 12.5 0.2 1.2 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP Integrin_beta PF00362.18 KIK48765.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 1 0 1 1 1 0 Integrin beta chain VWA domain Sld5 PF05916.11 KIK48766.1 - 0.00024 21.5 0.0 0.00033 21.1 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Pkr1 PF08636.10 KIK48767.1 - 2.1e-18 66.2 4.9 2.8e-18 65.8 4.9 1.1 1 0 0 1 1 1 1 ER protein Pkr1 UPF0154 PF03672.13 KIK48767.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) DUF4191 PF13829.6 KIK48767.1 - 0.14 11.4 0.8 0.16 11.3 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Pkinase_Tyr PF07714.17 KIK48770.1 - 3.6e-34 118.2 0.0 4.1e-31 108.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KIK48770.1 - 3.9e-29 101.8 0.0 1.2e-27 97.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain TMEM214 PF10151.9 KIK48770.1 - 0.005 15.4 0.5 0.007 14.9 0.5 1.1 1 0 0 1 1 1 1 TMEM214, C-terminal, caspase 4 activator MDM10 PF12519.8 KIK48772.1 - 1.4e-99 334.1 0.5 9.3e-88 295.1 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 KIK48772.1 - 0.0058 16.1 0.0 5.7 6.3 0.0 3.1 4 0 0 4 4 4 2 Eukaryotic porin DUF591 PF04569.14 KIK48772.1 - 0.18 11.9 0.9 0.59 10.2 0.9 1.8 1 1 0 1 1 1 0 Protein of unknown function Pea-VEAacid PF08111.11 KIK48773.1 - 0.14 12.6 0.1 0.34 11.3 0.1 1.6 1 0 0 1 1 1 0 Pea-VEAacid family LSM PF01423.22 KIK48774.1 - 1.5e-19 69.4 0.0 1.7e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KIK48774.1 - 0.043 13.5 0.0 0.062 13.0 0.0 1.3 1 1 0 1 1 1 0 Hfq protein PPR_3 PF13812.6 KIK48775.1 - 0.0098 16.0 0.0 1.8 8.7 0.0 3.1 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 KIK48775.1 - 0.027 14.6 0.0 10 6.4 0.0 3.2 3 0 0 3 3 3 0 PPR repeat family AAA PF00004.29 KIK48776.1 - 1.8e-30 106.1 0.0 3.5e-30 105.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIK48776.1 - 1.5e-07 31.7 0.1 2.7e-06 27.7 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KIK48776.1 - 6.3e-07 29.9 0.2 3.3e-06 27.6 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KIK48776.1 - 6e-06 26.8 0.0 1.6e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KIK48776.1 - 5.6e-05 23.3 0.0 0.0001 22.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KIK48776.1 - 0.00013 22.0 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KIK48776.1 - 0.00032 20.0 0.1 0.0065 15.7 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 KIK48776.1 - 0.00036 20.7 0.0 0.00064 19.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIK48776.1 - 0.00078 19.3 0.1 0.0021 17.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KIK48776.1 - 0.0011 18.6 0.2 0.34 10.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain ATPase_2 PF01637.18 KIK48776.1 - 0.0013 18.7 0.0 0.96 9.3 0.0 2.2 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea AAA_28 PF13521.6 KIK48776.1 - 0.0014 18.9 0.0 0.0037 17.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KIK48776.1 - 0.0019 17.9 0.1 0.0054 16.5 0.1 1.9 2 1 0 2 2 2 1 Cytidylate kinase AAA_5 PF07728.14 KIK48776.1 - 0.002 18.1 0.1 0.005 16.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KIK48776.1 - 0.0021 17.9 0.0 0.0067 16.2 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KIK48776.1 - 0.0024 17.9 0.0 0.0048 16.9 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KIK48776.1 - 0.0033 17.3 0.2 0.0095 15.9 0.1 2.0 2 1 0 2 2 1 1 NACHT domain AAA_30 PF13604.6 KIK48776.1 - 0.0037 17.0 0.0 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KIK48776.1 - 0.0037 17.0 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KIK48776.1 - 0.004 17.5 0.0 0.0092 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 KIK48776.1 - 0.0064 16.2 0.0 0.019 14.7 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 KIK48776.1 - 0.0065 16.2 0.0 0.014 15.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KIK48776.1 - 0.012 15.1 0.0 0.035 13.6 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region TIP49 PF06068.13 KIK48776.1 - 0.012 14.8 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_19 PF13245.6 KIK48776.1 - 0.029 14.7 0.0 0.18 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KIK48776.1 - 0.029 14.8 0.0 0.092 13.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 KIK48776.1 - 0.039 14.5 0.0 0.065 13.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.14 KIK48776.1 - 0.045 13.0 0.1 4.7 6.4 0.1 2.2 1 1 0 2 2 2 0 KAP family P-loop domain Mg_chelatase PF01078.21 KIK48776.1 - 0.053 12.9 0.0 0.12 11.8 0.0 1.5 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KIK48776.1 - 0.057 13.3 0.1 0.16 11.9 0.1 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_3 PF07726.11 KIK48776.1 - 0.079 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 KIK48776.1 - 0.09 11.4 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KIK48776.1 - 0.09 13.3 0.0 0.25 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KIK48776.1 - 0.097 12.4 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATPase PF06745.13 KIK48776.1 - 0.098 12.0 0.0 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 KaiC CPT PF07931.12 KIK48776.1 - 0.12 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.15 KIK48776.1 - 0.34 10.8 1.0 1.2 9.0 0.0 2.3 3 0 0 3 3 3 0 NTPase Rdx PF10262.9 KIK48777.1 - 3.1e-24 85.0 0.0 3.8e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Rdx family CLASP_N PF12348.8 KIK48778.1 - 6.7e-69 231.9 1.0 3.8e-64 216.4 0.1 4.8 5 0 0 5 5 5 2 CLASP N terminal Cnd1 PF12717.7 KIK48778.1 - 0.0001 22.4 0.2 0.38 10.8 0.0 3.5 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KIK48778.1 - 0.0002 21.4 0.5 4.1 7.9 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat Cohesin_HEAT PF12765.7 KIK48778.1 - 0.27 11.6 3.1 8.5 6.8 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Rhomboid PF01694.22 KIK48779.1 - 6.9e-24 84.5 8.7 1.1e-23 83.9 8.7 1.4 1 0 0 1 1 1 1 Rhomboid family Sedlin_N PF04628.13 KIK48780.1 - 7.9e-35 119.8 0.0 3.6e-34 117.7 0.0 1.8 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KIK48780.1 - 1.4e-08 34.8 0.0 2.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family NINJA_B PF16136.5 KIK48780.1 - 0.23 11.9 0.6 0.35 11.3 0.6 1.2 1 0 0 1 1 1 0 Putative nuclear localisation signal DUF508 PF04370.12 KIK48780.1 - 0.98 9.2 3.3 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF508) Actin PF00022.19 KIK48782.1 - 2e-117 392.3 0.0 2.2e-117 392.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KIK48782.1 - 7.2e-05 21.7 0.0 0.027 13.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein BOP1NT PF08145.12 KIK48783.1 - 2e-101 339.3 8.1 2.7e-101 338.9 8.1 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KIK48783.1 - 1.1e-19 70.4 5.7 0.00073 20.3 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK48783.1 - 6.2e-08 32.8 0.9 0.1 12.9 0.2 4.7 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain SDA1 PF05285.12 KIK48783.1 - 2.5 7.4 13.4 3.3 7.0 13.4 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KIK48783.1 - 2.6 7.3 12.8 3.5 6.9 12.8 1.2 1 0 0 1 1 1 0 BUD22 PDCD2_C PF04194.13 KIK48783.1 - 7.6 6.6 7.9 1.5e+02 2.4 7.7 2.2 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain DUF2423 PF10338.9 KIK48785.1 - 8.7e-16 57.9 4.3 1.9e-15 56.8 4.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Laps PF10169.9 KIK48785.1 - 0.00087 19.9 3.0 0.001 19.7 3.0 1.2 1 0 0 1 1 1 1 Learning-associated protein bZIP_2 PF07716.15 KIK48785.1 - 0.042 13.9 1.7 0.096 12.8 1.7 1.7 1 0 0 1 1 1 0 Basic region leucine zipper LSM PF01423.22 KIK48786.1 - 2.3e-21 75.2 0.0 2.6e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIK48786.1 - 0.003 17.6 0.0 0.0035 17.4 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain CBFD_NFYB_HMF PF00808.23 KIK48787.1 - 7.3e-20 71.0 0.9 1.5e-19 70.1 0.9 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2458 PF10454.9 KIK48787.1 - 0.0069 16.1 0.4 0.01 15.5 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) PfkB PF00294.24 KIK48788.1 - 4.6e-15 55.7 0.0 6.2e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KIK48788.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase ACPS PF01648.20 KIK48789.1 - 6.6e-14 52.0 0.0 1.5e-13 50.9 0.0 1.6 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily F-box-like PF12937.7 KIK48790.1 - 5.7e-06 26.1 0.6 1.2e-05 25.0 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIK48790.1 - 7.2e-06 25.9 0.3 7.2e-06 25.9 0.3 1.9 2 0 0 2 2 2 1 F-box F-box PF00646.33 KIK48790.1 - 0.00017 21.3 0.4 0.00065 19.5 0.1 2.1 3 0 0 3 3 3 1 F-box domain tRNA-synt_2 PF00152.20 KIK48791.1 - 5.7e-87 291.7 0.0 2.5e-86 289.6 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIK48791.1 - 1.7e-06 27.9 0.0 3.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain IMD PF08397.11 KIK48792.1 - 7.6e-07 28.7 1.6 1.4e-06 27.9 1.6 1.4 1 0 0 1 1 1 1 IRSp53/MIM homology domain Spc7 PF08317.11 KIK48792.1 - 0.0054 15.6 0.8 0.0076 15.2 0.8 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein OmpH PF03938.14 KIK48792.1 - 0.059 13.7 2.1 0.1 12.9 2.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ARD PF03079.14 KIK48792.1 - 0.15 12.3 0.9 0.25 11.5 0.9 1.3 1 0 0 1 1 1 0 ARD/ARD' family Mak16 PF04874.14 KIK48792.1 - 0.35 11.5 3.1 4.5 7.9 1.5 2.3 1 1 1 2 2 2 0 Mak16 protein C-terminal region Ribosomal_L19 PF01245.20 KIK48793.1 - 9e-14 51.4 0.0 1.4e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 RRM_1 PF00076.22 KIK48794.1 - 2.6e-17 62.4 0.0 5.9e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.18 KIK48798.1 - 1.1e-33 116.4 0.0 1.6e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK48798.1 - 3.5e-08 33.4 15.8 6.7e-08 32.5 15.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 KIK48799.1 - 1.2e-26 93.7 1.8 2e-26 93.0 1.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIK48799.1 - 1.2e-19 70.3 0.0 1e-18 67.3 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KIK48799.1 - 7.4e-12 45.7 2.8 1.3e-11 44.9 2.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KIK48799.1 - 2e-11 44.6 0.0 6.5e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 KIK48799.1 - 0.018 14.7 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal UPF0489 PF12640.7 KIK48799.1 - 0.044 14.0 0.0 0.073 13.3 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain Pkinase PF00069.25 KIK48801.1 - 1.1e-67 228.2 0.0 1.5e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK48801.1 - 3.7e-30 105.1 0.0 5.3e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KIK48801.1 - 2.9e-16 59.9 0.3 2.9e-16 59.9 0.3 3.1 3 1 0 3 3 3 1 Protein kinase C terminal domain Kinase-like PF14531.6 KIK48801.1 - 1.7e-08 34.1 0.0 4.5e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like C2 PF00168.30 KIK48801.1 - 2.8e-07 30.8 0.2 0.0012 19.0 0.1 2.4 2 0 0 2 2 2 2 C2 domain Haspin_kinase PF12330.8 KIK48801.1 - 1.5e-06 27.4 0.1 1.5e-06 27.4 0.1 2.1 1 1 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 KIK48801.1 - 0.0029 17.3 0.1 0.34 10.5 0.1 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIK48801.1 - 0.0053 16.1 0.0 0.0097 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK48801.1 - 0.0088 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Suc_Fer-like PF06999.12 KIK48802.1 - 9e-53 179.0 0.0 1.2e-52 178.6 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like MRP-S26 PF14943.6 KIK48803.1 - 0.00018 21.5 0.1 0.00058 19.8 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ribosome subunit S26 DDE_3 PF13358.6 KIK48805.1 - 0.031 14.0 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF1730 PF08331.10 KIK48806.1 - 0.13 12.2 0.1 0.33 10.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) RRM_1 PF00076.22 KIK48807.1 - 1.3e-10 40.9 0.0 6.1e-07 29.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KIK48807.1 - 0.063 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 KIK48807.1 - 0.064 13.2 0.0 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Complex1_LYR_2 PF13233.6 KIK48808.1 - 7.1e-15 55.5 0.8 8.4e-15 55.3 0.8 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Sua5_yciO_yrdC PF01300.18 KIK48809.1 - 3.7e-51 173.1 0.0 7.9e-51 172.1 0.0 1.5 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.13 KIK48809.1 - 7.5e-29 101.0 0.0 1.1e-28 100.5 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding HMG_box PF00505.19 KIK48811.1 - 1.1e-14 54.6 0.9 1.7e-14 54.0 0.9 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIK48811.1 - 0.0048 17.5 0.2 0.01 16.4 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain DEAD PF00270.29 KIK48812.1 - 1e-45 155.7 0.0 1.6e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK48812.1 - 1.1e-24 87.0 0.0 2.8e-24 85.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK48812.1 - 0.029 14.4 0.0 0.051 13.6 0.0 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Mob1_phocein PF03637.17 KIK48815.1 - 2.1e-78 262.2 0.0 2.4e-78 262.0 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family DJ-1_PfpI PF01965.24 KIK48816.1 - 5.6e-16 58.8 0.0 8.8e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KIK48816.1 - 0.0006 19.5 0.0 0.0096 15.6 0.0 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like LcrG PF07216.12 KIK48816.1 - 0.07 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 LcrG protein RRM_1 PF00076.22 KIK48817.1 - 3.2e-18 65.3 0.1 9.8e-08 31.7 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIK48817.1 - 0.0047 16.8 0.0 0.21 11.5 0.0 2.5 2 1 0 2 2 2 1 Occluded RNA-recognition motif Tau95_N PF17682.1 KIK48817.1 - 0.016 15.4 0.0 0.025 14.8 0.0 1.2 1 0 0 1 1 1 0 Tau95 Triple barrel domain RRM_5 PF13893.6 KIK48817.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RXT2_N PF08595.11 KIK48817.1 - 2.3 8.2 5.2 3.5 7.6 5.2 1.4 1 1 0 1 1 1 0 RXT2-like, N-terminal TRAM_LAG1_CLN8 PF03798.16 KIK48818.1 - 1.6e-45 155.3 24.0 2.5e-45 154.7 24.0 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 KIK48818.1 - 6.8e-10 38.5 0.1 6.8e-10 38.5 0.1 2.8 3 0 0 3 3 3 1 TRAM1-like protein Snf7 PF03357.21 KIK48819.1 - 1.7e-31 109.2 25.1 2.1e-31 108.9 24.9 1.3 1 1 0 1 1 1 1 Snf7 Cut8 PF08559.10 KIK48819.1 - 0.032 13.8 5.4 0.043 13.4 5.4 1.2 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein Ribosomal_60s PF00428.19 KIK48819.1 - 0.69 10.5 11.5 1.7 9.3 3.4 2.8 2 1 1 3 3 3 0 60s Acidic ribosomal protein NIF PF03031.18 KIK48820.1 - 5.2e-53 179.0 0.0 7.1e-53 178.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase MFS_1 PF07690.16 KIK48821.1 - 1e-33 116.7 26.3 3e-29 102.1 17.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4079 PF13301.6 KIK48821.1 - 0.0082 16.3 3.0 0.02 15.1 0.1 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF4079) zf-rbx1 PF12678.7 KIK48822.1 - 4.8e-07 30.0 1.0 6.7e-07 29.5 1.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KIK48822.1 - 5.9e-07 29.3 0.1 1.1e-06 28.4 0.1 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK48822.1 - 7.2e-07 29.5 5.4 1.3e-05 25.4 5.4 2.1 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KIK48822.1 - 1.6e-06 28.0 0.4 6.5e-06 26.1 0.3 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIK48822.1 - 8.5e-06 25.5 1.0 0.00017 21.3 0.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK48822.1 - 1.1e-05 25.2 1.7 2.2e-05 24.2 0.3 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KIK48822.1 - 2.7e-05 23.9 2.1 0.00016 21.4 0.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK48822.1 - 8.7e-05 22.4 1.6 0.00017 21.5 1.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 KIK48822.1 - 0.00034 20.3 0.8 0.0015 18.3 0.2 2.2 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KIK48822.1 - 0.0011 19.0 2.4 0.0026 17.7 2.4 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KIK48822.1 - 0.012 15.8 0.5 0.012 15.8 0.5 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KIK48822.1 - 0.088 12.7 1.3 0.21 11.5 0.4 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein FANCL_C PF11793.8 KIK48822.1 - 0.13 12.5 2.6 1.8 8.8 2.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain tRNA-synt_2c PF01411.19 KIK48823.1 - 1.6e-07 30.3 0.0 2.2e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KIK48823.1 - 0.02 15.0 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 Threonyl and Alanyl tRNA synthetase second additional domain MFS_1 PF07690.16 KIK48824.1 - 7.9e-39 133.6 27.7 7.9e-39 133.6 27.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KIK48825.1 - 1.8e-34 119.2 28.1 1.8e-34 119.2 28.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Mannosidase_ig PF17786.1 KIK48826.1 - 3.5e-19 69.2 0.1 2.5e-18 66.5 0.0 2.5 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KIK48826.1 - 3.9e-08 34.0 0.0 1.3e-07 32.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 KIK48826.1 - 0.00038 20.1 0.0 0.0023 17.6 0.0 2.2 2 0 0 2 2 2 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 KIK48826.1 - 0.00075 19.4 0.0 0.0022 17.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Big_3_2 PF12245.8 KIK48826.1 - 0.024 14.9 0.0 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain NOT2_3_5 PF04153.18 KIK48826.1 - 0.095 12.8 0.8 3.5 7.7 0.4 2.3 2 0 0 2 2 2 0 NOT2 / NOT3 / NOT5 family Ras PF00071.22 KIK48827.1 - 2e-44 151.1 0.1 2.2e-44 150.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK48827.1 - 1.5e-15 57.5 0.0 2e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK48827.1 - 1e-05 25.1 0.0 1.1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIK48827.1 - 0.00091 19.3 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIK48827.1 - 0.0012 18.5 0.1 0.0059 16.2 0.1 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIK48827.1 - 0.0021 18.0 0.1 1.5 8.7 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase AAA_14 PF13173.6 KIK48827.1 - 0.01 15.9 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIK48827.1 - 0.07 13.0 0.1 0.11 12.4 0.1 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Spo12 PF05032.12 KIK48828.1 - 1.7e-15 56.6 0.4 1.7e-15 56.6 0.4 2.2 3 0 0 3 3 3 1 Spo12 family Phage_tail_S PF05069.13 KIK48828.1 - 0.03 14.2 0.1 0.04 13.8 0.1 1.2 1 0 0 1 1 1 0 Phage virion morphogenesis family zf-C3HC4 PF00097.25 KIK48829.1 - 9.2e-08 31.8 0.3 2.2e-07 30.6 0.3 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK48829.1 - 5e-07 29.9 4.1 1.2e-05 25.6 1.9 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIK48829.1 - 1.9e-06 27.6 2.8 4.2e-05 23.3 0.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK48829.1 - 2.3e-06 27.5 0.1 5.9e-06 26.2 0.1 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zinc_ribbon_9 PF14369.6 KIK48829.1 - 8e-06 26.0 1.8 0.024 14.9 0.2 2.4 2 0 0 2 2 2 2 zinc-ribbon zf-RING_5 PF14634.6 KIK48829.1 - 8.3e-06 25.7 1.2 0.00056 19.8 0.7 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIK48829.1 - 1.1e-05 25.1 1.3 0.00043 20.1 0.2 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KIK48829.1 - 3.5e-05 23.6 2.3 0.00071 19.4 0.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIK48829.1 - 0.00034 20.8 6.2 0.002 18.4 6.5 2.0 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KIK48829.1 - 0.00099 18.9 1.0 0.012 15.4 0.5 2.2 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KIK48829.1 - 0.0036 17.3 0.3 0.036 14.1 0.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 KIK48829.1 - 0.0089 15.8 2.8 0.046 13.5 2.8 2.0 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KIK48829.1 - 0.0098 16.0 4.6 0.022 14.9 1.1 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-met2 PF12907.7 KIK48829.1 - 0.08 13.1 1.0 12 6.2 0.1 2.3 2 0 0 2 2 2 0 Zinc-binding Rad50_zn_hook PF04423.14 KIK48829.1 - 0.088 12.7 1.5 1.7 8.5 0.0 2.9 2 1 1 3 3 3 0 Rad50 zinc hook motif zf-UDP PF14569.6 KIK48829.1 - 0.097 12.8 2.2 1 9.5 2.2 2.1 1 1 0 1 1 1 0 Zinc-binding RING-finger Chitin_synth_1 PF01644.17 KIK48830.1 - 2.9e-67 225.7 0.0 4.5e-67 225.1 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KIK48830.1 - 1.6e-28 98.4 0.0 3.1e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KIK48830.1 - 4.5e-23 81.7 0.5 2.3e-18 66.2 0.1 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KIK48830.1 - 8.5e-07 29.1 7.3 5.3e-06 26.5 7.3 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Polyketide_cyc PF03364.20 KIK48832.1 - 1e-22 80.7 0.0 1.4e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport zf-CCHC PF00098.23 KIK48833.1 - 2.1e-25 87.6 31.5 2.4e-07 30.5 1.7 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 KIK48833.1 - 5.9e-09 35.5 17.9 0.0032 17.2 0.9 4.6 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_6 PF15288.6 KIK48833.1 - 2.2e-06 27.4 18.8 0.0035 17.2 0.7 4.4 3 1 1 4 4 4 4 Zinc knuckle zf-CCHC_3 PF13917.6 KIK48833.1 - 0.0023 17.9 16.1 0.8 9.7 1.2 4.1 2 1 2 4 4 4 3 Zinc knuckle Mu-like_Com PF10122.9 KIK48833.1 - 0.045 13.2 9.5 0.64 9.5 0.2 3.3 2 1 1 3 3 3 0 Mu-like prophage protein Com DZR PF12773.7 KIK48833.1 - 0.6 10.2 20.0 26 4.9 4.3 3.3 1 1 1 2 2 2 0 Double zinc ribbon HscB_4_cys PF18256.1 KIK48833.1 - 1.9 8.4 15.4 14 5.6 0.1 4.6 4 0 0 4 4 4 0 Co-chaperone HscB tetracysteine metal binding motif YhfH PF14149.6 KIK48833.1 - 9.2 6.3 16.4 0.75 9.8 0.3 3.8 4 0 0 4 4 4 0 YhfH-like protein Aminotran_1_2 PF00155.21 KIK48835.1 - 3.8e-17 62.5 0.0 2.6e-12 46.6 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II 14-3-3 PF00244.20 KIK48836.1 - 3.3e-76 255.7 3.8 3.8e-76 255.5 3.8 1.0 1 0 0 1 1 1 1 14-3-3 protein DS PF01916.17 KIK48837.1 - 1.3e-137 457.8 0.0 1.5e-137 457.6 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Sec7 PF01369.20 KIK48838.1 - 9.2e-70 234.0 0.5 2.3e-69 232.7 0.1 2.0 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 KIK48838.1 - 2.3e-45 154.3 4.7 2.3e-45 154.3 4.7 2.7 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KIK48838.1 - 5.2e-33 112.8 0.2 5.2e-33 112.8 0.2 5.9 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 KIK48838.1 - 1.3e-20 73.8 2.6 3.8e-18 65.8 0.2 3.4 4 0 0 4 4 4 2 Dimerisation and cyclophilin-binding domain of Mon2 Cas_APE2256 PF09651.10 KIK48838.1 - 0.018 15.0 0.1 0.072 13.0 0.0 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_APE2256) TFCD_C PF12612.8 KIK48838.1 - 0.084 12.7 0.4 0.3 10.9 0.1 2.2 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal SH3_1 PF00018.28 KIK48839.1 - 2.5e-40 135.8 6.5 9.1e-15 54.0 0.3 4.3 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 KIK48839.1 - 1.3e-38 130.6 6.3 2.7e-12 46.3 0.1 4.3 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.12 KIK48839.1 - 5.2e-30 103.1 0.0 9.8e-30 102.2 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 KIK48839.1 - 4.2e-28 96.8 0.6 9.2e-08 31.7 0.0 4.7 4 0 0 4 4 4 4 Variant SH3 domain hSH3 PF14603.6 KIK48839.1 - 9.7e-06 25.9 0.0 0.012 16.1 0.0 3.0 3 0 0 3 3 3 2 Helically-extended SH3 domain SAM_4 PF18017.1 KIK48839.1 - 1.4e-05 24.9 0.0 2.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 KIK48839.1 - 1.9e-05 24.7 0.1 0.26 11.4 0.0 3.8 3 0 0 3 3 3 1 SH3 domain SH3_3 PF08239.11 KIK48839.1 - 3e-05 24.2 9.0 0.66 10.3 0.0 3.8 4 0 0 4 4 4 3 Bacterial SH3 domain CDC45 PF02724.14 KIK48839.1 - 1.8 6.7 19.3 3.1 6.0 19.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KIK48839.1 - 4.2 6.0 14.3 8.8 5.0 14.3 1.6 1 0 0 1 1 1 0 Presenilin SCA7 PF08313.12 KIK48840.1 - 4.8e-29 100.1 0.4 4.8e-29 100.1 0.4 2.1 2 0 0 2 2 2 1 SCA7, zinc-binding domain ADC PF06314.11 KIK48840.1 - 0.051 13.1 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetoacetate decarboxylase (ADC) DUF4407 PF14362.6 KIK48840.1 - 0.057 12.8 3.0 0.086 12.2 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DSBA PF01323.20 KIK48840.1 - 0.11 12.3 0.2 0.24 11.2 0.2 1.6 1 1 0 1 1 1 0 DSBA-like thioredoxin domain zf_UBZ PF18439.1 KIK48840.1 - 0.16 11.6 0.1 0.35 10.5 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-TRAF PF02176.18 KIK48840.1 - 0.16 12.7 1.0 0.76 10.5 0.1 2.1 2 0 0 2 2 2 0 TRAF-type zinc finger RNA_pol_Rpc4 PF05132.14 KIK48840.1 - 4.7 7.6 8.5 5.6 7.4 1.6 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 GTP_EFTU PF00009.27 KIK48841.1 - 2.4e-45 154.5 0.0 3.2e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KIK48841.1 - 8.5e-35 119.4 0.1 9.1e-34 116.1 0.0 2.5 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KIK48841.1 - 1.6e-09 38.0 0.1 4.5e-09 36.6 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIK48841.1 - 0.00098 19.2 0.1 0.005 16.9 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase RTP1_C1 PF10363.9 KIK48842.1 - 5.5e-27 94.2 0.0 2.7e-26 91.9 0.0 2.3 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 KIK48842.1 - 0.085 12.6 0.2 0.25 11.1 0.2 1.9 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 HEAT_2 PF13646.6 KIK48842.1 - 0.25 11.7 6.1 2.6 8.5 0.1 4.6 5 0 0 5 5 5 0 HEAT repeats HSP90 PF00183.18 KIK48843.1 - 1.1e-139 466.7 1.3 1.4e-139 466.3 1.3 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 KIK48843.1 - 1.9e-07 31.0 0.0 5.9e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KIK48843.1 - 1.2e-05 25.8 0.0 2.7e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3106 PF11304.8 KIK48843.1 - 0.077 13.5 0.2 0.21 12.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) FF PF01846.19 KIK48844.1 - 3.3e-38 129.6 25.0 4e-11 42.9 0.1 6.9 7 0 0 7 7 7 5 FF domain RhoGAP-FF1 PF16512.5 KIK48844.1 - 7e-09 36.2 5.4 0.022 15.5 0.0 4.5 2 2 1 3 3 3 3 p190-A and -B Rho GAPs FF domain WW PF00397.26 KIK48844.1 - 2e-08 34.2 14.2 2.3e-07 30.8 2.3 3.2 3 0 0 3 3 3 2 WW domain E1-E2_ATPase PF00122.20 KIK48846.1 - 2.1e-45 154.5 0.4 2.1e-45 154.5 0.4 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KIK48846.1 - 2.1e-33 116.4 0.4 4.2e-33 115.4 0.4 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KIK48846.1 - 1.1e-18 67.4 1.7 8.7e-12 45.3 0.2 3.6 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KIK48846.1 - 0.00052 19.8 0.5 0.0037 17.0 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIK48846.1 - 0.002 18.6 0.0 0.0041 17.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3795 PF12675.7 KIK48846.1 - 0.5 10.8 1.8 20 5.7 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3795) GCP_N_terminal PF17681.1 KIK48847.1 - 3.5e-98 329.0 0.0 2.6e-97 326.2 0.0 2.2 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KIK48847.1 - 5.2e-91 305.3 1.7 1.3e-90 304.0 1.7 1.7 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal MFS_1 PF07690.16 KIK48849.1 - 5.3e-40 137.4 43.3 5.3e-40 137.4 43.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK48849.1 - 1.6e-07 30.6 1.1 1.6e-07 30.6 1.1 3.8 2 2 2 4 4 4 2 Sugar (and other) transporter MFS_3 PF05977.13 KIK48849.1 - 0.00024 19.6 7.8 0.0004 18.9 7.8 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector BacteriocIIc_cy PF12173.8 KIK48849.1 - 0.031 14.5 7.9 0.063 13.5 0.5 3.5 3 1 1 4 4 4 0 Bacteriocin class IIc cyclic gassericin A-like E1-E2_ATPase PF00122.20 KIK48849.1 - 6.4 6.2 5.6 0.92 9.0 0.5 2.2 2 0 0 2 2 2 0 E1-E2 ATPase RasGAP_C PF03836.15 KIK48850.1 - 5.3e-47 159.4 1.5 5.3e-47 159.4 1.5 2.1 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.19 KIK48850.1 - 3.3e-39 134.7 0.1 8.6e-39 133.4 0.0 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.27 KIK48850.1 - 3.7e-19 66.7 66.5 0.0013 18.4 0.1 13.2 13 0 0 13 13 13 10 IQ calmodulin-binding motif CH PF00307.31 KIK48850.1 - 1.9e-11 44.1 0.0 8.3e-11 42.0 0.0 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain Sipho_Gp157 PF05565.11 KIK48850.1 - 0.2 11.7 3.4 0.2 11.7 0.3 2.3 2 0 0 2 2 2 0 Siphovirus Gp157 Tropomyosin_1 PF12718.7 KIK48850.1 - 1.4 9.1 5.6 11 6.2 0.4 2.9 3 0 0 3 3 3 0 Tropomyosin like Med12 PF09497.10 KIK48851.1 - 0.03 14.6 0.0 0.035 14.4 0.0 1.2 1 0 0 1 1 1 0 Transcription mediator complex subunit Med12 E1-E2_ATPase PF00122.20 KIK48852.1 - 2.1e-45 154.4 0.5 2.1e-45 154.4 0.5 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KIK48852.1 - 5.5e-34 118.3 0.4 1.3e-33 117.1 0.4 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KIK48852.1 - 2.1e-24 85.7 4.0 4.5e-11 43.0 0.4 3.6 3 0 0 3 3 3 3 Heavy-metal-associated domain HAD PF12710.7 KIK48852.1 - 0.0005 20.5 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KIK48852.1 - 0.0021 17.8 0.3 0.019 14.7 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase His_Phos_2 PF00328.22 KIK48853.1 - 6e-89 299.1 0.1 7.9e-89 298.7 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KIK48853.1 - 2.1e-37 127.2 0.6 4.4e-37 126.1 0.1 1.9 2 0 0 2 2 2 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KIK48853.1 - 4.3e-06 26.5 0.0 7.7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain UQ_con PF00179.26 KIK48854.1 - 1.9e-18 66.4 0.1 2.7e-18 66.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KIK48854.1 - 0.017 15.4 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain BRE PF06113.12 KIK48854.1 - 0.046 12.6 0.1 0.061 12.2 0.1 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) MFS_1 PF07690.16 KIK48855.1 - 1.6e-35 122.7 25.6 1.6e-35 122.7 25.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily zf-CCHC PF00098.23 KIK48856.1 - 1.5e-05 24.8 38.5 0.00056 19.9 5.0 5.0 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_2 PF13696.6 KIK48856.1 - 0.23 11.3 0.2 0.23 11.3 0.2 5.0 5 0 0 5 5 5 0 Zinc knuckle DUF1451 PF07295.11 KIK48856.1 - 0.32 11.0 11.0 1 9.4 0.2 2.7 2 1 0 2 2 2 0 Zinc-ribbon containing domain HypA PF01155.19 KIK48856.1 - 4.3 7.4 18.3 6.2e+02 0.4 14.2 3.1 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CCHC_3 PF13917.6 KIK48856.1 - 5.8 7.0 23.8 0.28 11.2 2.6 4.5 3 1 1 4 4 4 0 Zinc knuckle ABC_tran PF00005.27 KIK48857.1 - 3.7e-18 66.4 0.0 7.9e-18 65.3 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIK48857.1 - 1e-10 41.9 0.9 2.6e-05 24.2 0.3 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIK48857.1 - 0.00026 20.7 0.1 0.00062 19.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIK48857.1 - 0.00042 20.3 0.0 0.00061 19.7 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 KIK48857.1 - 0.0035 17.9 0.1 0.0063 17.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KIK48857.1 - 0.0044 16.6 0.0 0.0075 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KIK48857.1 - 0.0046 16.7 0.0 0.0062 16.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KIK48857.1 - 0.005 16.3 0.1 0.44 10.0 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain SRP54 PF00448.22 KIK48857.1 - 0.025 14.2 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 KIK48857.1 - 0.026 14.3 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KIK48857.1 - 0.044 13.9 0.1 0.078 13.1 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KIK48857.1 - 0.053 13.8 0.0 0.12 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIK48857.1 - 0.066 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KIK48857.1 - 0.069 12.4 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 KIK48857.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KIK48857.1 - 0.12 12.3 0.1 0.3 11.0 0.2 1.5 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 KIK48857.1 - 0.19 12.1 0.0 0.71 10.3 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Opy2 PF09463.10 KIK48858.1 - 2.7e-06 27.6 22.4 5e-06 26.7 22.4 1.5 1 0 0 1 1 1 1 Opy2 protein VSP PF03302.13 KIK48858.1 - 0.00025 20.0 5.3 0.0004 19.4 5.3 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Phage_holin_2_4 PF16082.5 KIK48858.1 - 0.0032 17.1 0.1 0.0065 16.2 0.1 1.4 1 0 0 1 1 1 1 Bacteriophage holin family, superfamily II-like DUF4381 PF14316.6 KIK48858.1 - 0.035 14.4 0.5 0.07 13.4 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4366 PF14283.6 KIK48858.1 - 0.075 13.1 0.1 0.32 11.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) SNARE_assoc PF09335.11 KIK48858.1 - 0.11 13.0 0.1 0.19 12.2 0.1 1.3 1 0 0 1 1 1 0 SNARE associated Golgi protein Phage_holin_3_6 PF07332.11 KIK48858.1 - 0.13 12.3 0.4 0.25 11.4 0.4 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III SKG6 PF08693.10 KIK48858.1 - 1.5 8.3 5.6 3.2 7.2 5.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain UQ_con PF00179.26 KIK48859.1 - 1.2e-21 76.8 0.0 2.2e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 KIK48859.1 - 0.0016 18.3 0.6 0.0057 16.5 0.6 2.0 1 0 0 1 1 1 1 UBA/TS-N domain IBR PF01485.21 KIK48859.1 - 0.0018 18.4 3.6 0.0042 17.3 3.6 1.6 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain ATPase-cat_bd PF12156.8 KIK48859.1 - 0.054 14.2 0.1 0.13 13.0 0.1 1.6 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase zf-RanBP PF00641.18 KIK48860.1 - 0.1 11.9 0.2 0.15 11.4 0.2 1.2 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Mito_carr PF00153.27 KIK48861.1 - 2.9e-51 171.3 1.4 3.2e-16 59.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 KIK48861.1 - 7.5e-05 22.9 0.1 1.1 9.5 0.0 3.4 3 1 0 3 3 3 2 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase PrcB_C PF14343.6 KIK48861.1 - 0.01 15.9 0.0 7.6 6.8 0.0 2.5 2 0 0 2 2 2 0 PrcB C-terminal Sedlin_N PF04628.13 KIK48862.1 - 4.5e-17 62.4 0.0 5.5e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region F-box-like PF12937.7 KIK48863.1 - 1.9e-10 40.5 1.3 5.6e-10 39.0 1.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIK48863.1 - 0.0093 15.8 0.4 0.0093 15.8 0.4 3.9 2 1 2 4 4 4 1 F-box domain LRIF1 PF15741.5 KIK48864.1 - 0.27 9.7 6.7 0.43 9.1 6.7 1.2 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Med3 PF11593.8 KIK48864.1 - 1.3 8.1 9.2 3.5 6.7 9.2 1.7 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Kelch_4 PF13418.6 KIK48865.1 - 9.1e-13 48.0 9.3 4.5e-05 23.4 0.1 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KIK48865.1 - 7.7e-07 29.2 24.9 0.0048 17.2 0.4 6.6 7 0 0 7 7 7 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KIK48865.1 - 8.4e-06 25.6 5.3 1.3 9.1 0.0 5.0 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 KIK48865.1 - 2.2e-05 24.6 7.8 1.5 9.2 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 KIK48865.1 - 0.0022 17.9 10.7 0.044 13.8 0.1 5.4 6 0 0 6 6 6 1 Kelch motif Kelch_1 PF01344.25 KIK48865.1 - 0.0074 15.9 2.2 0.45 10.1 0.0 3.9 4 0 0 4 4 4 1 Kelch motif FliP PF00813.20 KIK48865.1 - 0.018 15.0 0.2 0.053 13.4 0.0 1.7 2 0 0 2 2 2 0 FliP family DUF2784 PF10861.8 KIK48865.1 - 0.59 10.2 7.5 1.3 9.1 7.5 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF2784) MgtE PF01769.16 KIK48865.1 - 1.7 9.0 6.3 0.81 10.1 1.5 2.3 2 0 0 2 2 2 0 Divalent cation transporter EVC2_like PF12297.8 KIK48865.1 - 2.3 6.8 3.7 2.1 6.9 0.1 2.0 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein Asp PF00026.23 KIK48866.1 - 1.4e-110 369.6 0.2 1.7e-110 369.4 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK48866.1 - 6.6e-15 55.8 0.7 9.4e-13 48.8 0.7 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KIK48866.1 - 6.2e-05 22.8 0.0 0.0012 18.7 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KIK48866.1 - 0.00019 22.0 0.0 0.14 12.8 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KIK48866.1 - 0.00032 21.2 0.0 0.14 12.7 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease WD40 PF00400.32 KIK48867.1 - 2e-15 56.9 6.9 0.00016 22.4 0.4 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK48867.1 - 0.066 13.5 0.0 0.9 9.9 0.0 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 KIK48868.1 - 3.9e-78 262.5 0.0 4.7e-78 262.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK48868.1 - 9.1e-39 133.3 0.0 1.2e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK48868.1 - 1.7e-06 27.6 0.0 1.6e-05 24.4 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KIK48868.1 - 0.00019 20.5 0.1 0.0023 16.9 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KIK48868.1 - 0.0026 17.1 0.0 0.0089 15.4 0.1 1.8 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK48868.1 - 0.0037 16.1 0.0 0.0062 15.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PCI PF01399.27 KIK48869.1 - 1.1e-10 41.9 0.2 9.9e-10 38.9 0.0 2.7 3 1 0 3 3 3 1 PCI domain LppC PF04348.13 KIK48869.1 - 0.00046 19.1 0.5 0.00066 18.6 0.5 1.2 1 0 0 1 1 1 1 LppC putative lipoprotein RPN7 PF10602.9 KIK48869.1 - 0.00069 19.4 0.4 0.0014 18.4 0.4 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 DUF410 PF04190.13 KIK48869.1 - 0.0053 16.6 0.1 0.011 15.5 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF410) TAFH PF07531.14 KIK48869.1 - 0.0095 16.0 0.6 0.097 12.8 0.1 2.6 2 0 0 2 2 2 1 NHR1 homology to TAF PUB PF09409.10 KIK48871.1 - 1.8e-09 37.4 0.1 2.8e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 PUB domain PAS_7 PF12860.7 KIK48871.1 - 0.16 12.1 0.6 0.34 11.1 0.4 1.6 2 0 0 2 2 2 0 PAS fold DUF3336 PF11815.8 KIK48872.1 - 9.6e-49 164.6 1.0 1.5e-48 164.1 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KIK48872.1 - 5.2e-20 72.5 0.7 8.9e-20 71.7 0.2 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase TadE PF07811.12 KIK48872.1 - 1.9 8.8 4.2 4.5 7.6 4.2 1.6 1 0 0 1 1 1 0 TadE-like protein TFIIS_C PF01096.18 KIK48873.1 - 1.1e-19 69.9 5.0 1.7e-19 69.4 5.0 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) PhnA_Zn_Ribbon PF08274.12 KIK48873.1 - 0.095 12.7 1.8 9.2 6.3 0.4 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon DUF3759 PF12585.8 KIK48874.1 - 7.6e-31 106.0 6.2 8.6e-31 105.8 6.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) ORC4_C PF14629.6 KIK48875.1 - 6.2e-26 91.1 0.0 9.3e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KIK48875.1 - 1.4e-14 54.8 0.1 4.5e-14 53.2 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIK48875.1 - 0.00044 20.7 0.0 0.0083 16.5 0.0 2.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KIK48875.1 - 0.012 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIK48875.1 - 0.026 14.8 0.0 0.081 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK48875.1 - 0.037 13.5 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KIK48875.1 - 0.042 13.8 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KIK48875.1 - 0.061 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.29 KIK48875.1 - 0.088 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase NACHT PF05729.12 KIK48875.1 - 0.095 12.6 0.0 16 5.4 0.0 2.8 3 0 0 3 3 3 0 NACHT domain AAA_14 PF13173.6 KIK48875.1 - 0.099 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIK48875.1 - 0.12 12.5 0.0 0.43 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain Med20 PF08612.11 KIK48876.1 - 8.1e-10 38.4 0.0 4.2e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex BCDHK_Adom3 PF10436.9 KIK48877.1 - 2.3e-43 147.8 0.0 3.5e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KIK48877.1 - 1.8e-08 34.8 0.0 4.8e-07 30.3 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KIK48877.1 - 0.026 14.4 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.25 KIK48880.1 - 8.5e-66 222.0 0.3 4.9e-43 147.4 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK48880.1 - 4.6e-29 101.5 0.3 9.2e-21 74.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KIK48880.1 - 3.7e-07 29.4 0.2 5.1e-07 29.0 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KIK48880.1 - 0.00023 20.6 0.5 0.0008 18.8 0.0 2.0 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIK48880.1 - 0.0012 18.2 0.9 0.0083 15.5 0.2 2.5 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 KIK48880.1 - 0.0088 16.0 2.9 0.024 14.5 0.2 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_C PF00433.24 KIK48880.1 - 0.016 15.9 0.1 0.036 14.8 0.1 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain Pkinase_fungal PF17667.1 KIK48880.1 - 0.028 13.2 0.2 0.082 11.7 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Seadorna_VP7 PF07387.11 KIK48880.1 - 0.047 12.7 0.0 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 KIK48880.1 - 0.067 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 KIK48880.1 - 0.075 12.0 0.2 0.16 10.9 0.1 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase DEAD PF00270.29 KIK48884.1 - 1.1e-38 132.8 0.0 5.8e-38 130.4 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 KIK48884.1 - 7.9e-25 86.9 0.1 1.7e-24 85.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 KIK48884.1 - 7.6e-20 71.3 0.0 2.2e-19 69.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK48884.1 - 3.1e-05 24.1 0.0 8.9e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SBF_like PF13593.6 KIK48884.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) DUF3818 PF12825.7 KIK48885.1 - 4.6e-127 423.7 0.0 6.3e-127 423.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KIK48885.1 - 1.2e-28 99.7 0.2 3e-28 98.4 0.2 1.7 1 0 0 1 1 1 1 PX-associated PX PF00787.24 KIK48885.1 - 6.6e-12 45.4 0.4 2e-10 40.6 0.1 3.0 2 1 0 2 2 2 1 PX domain BUD22 PF09073.10 KIK48885.1 - 0.42 9.9 6.0 0.75 9.1 6.0 1.4 1 0 0 1 1 1 0 BUD22 DUF1682 PF07946.14 KIK48887.1 - 4.6e-90 302.1 0.3 5.2e-90 301.9 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) SPG4 PF17325.2 KIK48887.1 - 0.27 12.3 4.6 0.51 11.5 4.6 1.3 1 0 0 1 1 1 0 Stationary phase protein 4 LON_substr_bdg PF02190.16 KIK48889.1 - 8.2e-22 78.1 0.0 1.8e-21 77.0 0.0 1.5 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KIK48889.1 - 2.5e-11 43.2 13.3 2.5e-11 43.2 13.3 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK48889.1 - 6.6e-09 35.7 24.0 1.4e-07 31.4 10.2 2.8 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KIK48889.1 - 3e-08 33.7 24.8 0.00024 21.2 13.0 2.5 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KIK48889.1 - 4.6e-08 32.8 22.8 2.8e-07 30.3 11.9 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK48889.1 - 2.5e-07 30.4 19.6 2.6e-07 30.4 6.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK48889.1 - 4.5e-07 29.7 25.3 5.3e-06 26.3 10.5 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 KIK48889.1 - 5.7e-07 29.8 11.5 5.7e-07 29.8 11.5 2.6 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 KIK48889.1 - 4.3e-05 23.3 7.2 4.3e-05 23.3 7.2 3.1 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KIK48889.1 - 0.00057 20.0 18.3 0.00073 19.6 6.0 2.3 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KIK48889.1 - 0.003 17.8 6.3 0.003 17.8 6.3 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-P11 PF03854.14 KIK48889.1 - 0.005 16.5 6.6 0.017 14.8 6.6 1.9 1 0 0 1 1 1 1 P-11 zinc finger zf-RING_4 PF14570.6 KIK48889.1 - 0.017 14.9 2.0 0.017 14.9 2.0 2.3 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain BUD22 PF09073.10 KIK48889.1 - 4 6.7 4.9 2.2 7.5 0.0 2.0 2 0 0 2 2 2 0 BUD22 zf-RING_6 PF14835.6 KIK48889.1 - 9.1 6.2 14.9 0.28 11.1 3.3 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein G6PD_C PF02781.16 KIK48890.1 - 9e-111 369.7 0.0 1.2e-110 369.3 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KIK48890.1 - 5.3e-60 203.1 0.0 7.8e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain FmiP_Thoc5 PF09766.9 KIK48891.1 - 5.1e-33 114.8 10.6 6.5e-33 114.5 10.6 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 GCN5L1 PF06320.13 KIK48891.1 - 1.1 9.4 7.8 0.93 9.7 1.7 2.3 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) UQ_con PF00179.26 KIK48892.1 - 6.2e-37 126.4 0.1 7.7e-37 126.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF2127 PF09900.9 KIK48895.1 - 0.0077 16.5 0.7 0.018 15.3 0.0 1.8 2 0 0 2 2 2 1 Predicted membrane protein (DUF2127) MARVEL PF01284.23 KIK48895.1 - 0.23 11.5 15.6 0.37 10.8 14.8 1.7 1 1 1 2 2 2 0 Membrane-associating domain AMP-binding PF00501.28 KIK48896.1 - 3e-33 115.1 0.0 4.3e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KIK48896.1 - 8.6e-05 22.4 1.4 0.00018 21.3 1.4 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KIK48896.1 - 0.00095 20.1 0.0 0.002 19.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Metallophos PF00149.28 KIK48898.1 - 1.1e-07 32.5 1.3 1.8e-07 31.9 1.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RFX_DNA_binding PF02257.15 KIK48899.1 - 1.1e-27 96.4 0.0 3e-27 95.1 0.0 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain NuDC PF16273.5 KIK48899.1 - 0.017 15.7 3.9 0.034 14.7 3.9 1.4 1 0 0 1 1 1 0 Nuclear distribution C domain UPF0184 PF03670.13 KIK48900.1 - 0.091 13.2 5.0 19 5.8 3.8 3.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) CALCOCO1 PF07888.11 KIK48900.1 - 0.11 11.4 31.0 1.8 7.3 23.2 2.3 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4140 PF13600.6 KIK48900.1 - 0.12 12.8 0.0 0.12 12.8 0.0 5.6 4 1 1 5 5 5 0 N-terminal domain of unknown function (DUF4140) OmpH PF03938.14 KIK48900.1 - 0.25 11.7 35.4 0.035 14.4 4.1 4.2 3 1 1 4 4 4 0 Outer membrane protein (OmpH-like) Ribosomal_S17e PF00833.18 KIK48900.1 - 0.67 9.9 5.9 0.092 12.7 1.2 2.0 2 0 0 2 2 2 0 Ribosomal S17 Baculo_p24 PF05073.12 KIK48900.1 - 3.1 7.5 6.4 1.4 8.6 0.9 2.4 1 1 1 2 2 2 0 Baculovirus P24 capsid protein DUF848 PF05852.11 KIK48900.1 - 6.4 6.9 14.0 0.25 11.5 4.4 3.3 3 1 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Ribosomal_L7Ae PF01248.26 KIK48901.1 - 4.8e-25 87.1 0.8 8.2e-25 86.4 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Cupin_8 PF13621.6 KIK48902.1 - 9.8e-65 218.8 0.0 1.3e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KIK48902.1 - 0.00072 19.1 0.2 0.0014 18.2 0.2 1.4 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KIK48902.1 - 0.0078 16.6 0.0 0.075 13.5 0.1 2.5 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KIK48902.1 - 0.053 13.2 0.1 0.35 10.6 0.0 2.1 2 0 0 2 2 2 0 Cupin domain Rad17 PF03215.15 KIK48903.1 - 2.2e-05 24.5 0.0 0.00029 20.8 0.0 2.6 3 0 0 3 3 3 1 Rad17 P-loop domain AAA PF00004.29 KIK48903.1 - 0.0032 17.9 0.0 0.041 14.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIK48903.1 - 0.03 14.7 0.0 0.12 12.8 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain HLH PF00010.26 KIK48904.1 - 3.2e-13 49.4 0.2 8.5e-13 48.1 0.2 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DMAP1 PF05499.12 KIK48904.1 - 0.031 14.2 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF4558 PF15104.6 KIK48904.1 - 2 8.5 3.8 4.2 7.5 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4558) TFIIF_alpha PF05793.12 KIK48905.1 - 4e-19 68.6 49.1 1.9e-14 53.2 41.8 3.9 2 1 1 3 3 3 3 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Polysacc_deac_1 PF01522.21 KIK48906.1 - 6.6e-22 77.7 0.0 1.1e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Pkinase PF00069.25 KIK48907.1 - 1.2e-69 234.6 0.0 1.7e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK48907.1 - 4.2e-46 157.3 0.0 6e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK48907.1 - 0.00017 21.0 0.0 0.0039 16.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KIK48907.1 - 0.00063 18.6 0.0 0.0015 17.4 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase HTH_WhiA PF02650.14 KIK48907.1 - 0.5 10.7 2.0 9 6.7 0.0 3.0 3 0 0 3 3 3 0 WhiA C-terminal HTH domain Ribosomal_L29 PF00831.23 KIK48908.1 - 8.5e-19 67.3 2.7 8.5e-19 67.3 2.7 2.3 2 1 0 2 2 2 1 Ribosomal L29 protein MRP-L47 PF06984.13 KIK48908.1 - 0.38 10.9 5.3 0.13 12.4 1.6 2.1 2 2 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Snapin_Pallidin PF14712.6 KIK48908.1 - 0.89 10.0 11.9 2.2 8.8 4.4 2.1 1 1 1 2 2 2 0 Snapin/Pallidin SieB PF14163.6 KIK48908.1 - 1.6 8.2 5.8 0.24 10.9 0.7 2.1 1 1 1 2 2 2 0 Super-infection exclusion protein B His_biosynth PF00977.21 KIK48909.1 - 9.5e-38 129.9 0.0 1.2e-37 129.5 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KIK48909.1 - 0.036 13.4 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Methyltransf_18 PF12847.7 KIK48909.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Fe-ADH PF00465.19 KIK48910.1 - 7.5e-89 298.1 0.0 9.6e-89 297.7 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KIK48910.1 - 2.1e-11 44.0 0.0 2.3e-07 30.8 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Asp PF00026.23 KIK48911.1 - 3.2e-29 102.4 1.4 1.7e-27 96.7 1.4 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease DUF1180 PF06679.12 KIK48911.1 - 0.0014 19.1 0.1 0.003 18.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) TAXi_N PF14543.6 KIK48911.1 - 0.0044 17.3 4.9 0.19 11.9 0.1 3.9 3 1 1 4 4 4 1 Xylanase inhibitor N-terminal SUR7 PF06687.12 KIK48911.1 - 0.0096 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 SUR7/PalI family PPR_2 PF13041.6 KIK48912.1 - 1.2e-18 67.0 3.2 1.9e-13 50.3 0.1 5.3 6 0 0 6 6 6 2 PPR repeat family PPR PF01535.20 KIK48912.1 - 5.8e-07 29.3 2.9 0.0013 18.8 0.1 5.4 5 0 0 5 5 5 1 PPR repeat PPR_3 PF13812.6 KIK48912.1 - 0.0035 17.4 0.0 0.13 12.3 0.0 2.7 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 KIK48912.1 - 0.0046 16.6 4.1 0.24 11.2 0.1 3.4 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 KIK48912.1 - 0.0057 16.0 0.1 7.2 5.9 0.0 3.6 3 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP COX5A PF02284.16 KIK48912.1 - 0.037 14.0 0.3 6.2 6.9 0.0 3.5 4 0 0 4 4 4 0 Cytochrome c oxidase subunit Va Ribophorin_I PF04597.14 KIK48913.1 - 3.4e-129 431.9 2.4 3.9e-129 431.7 2.4 1.0 1 0 0 1 1 1 1 Ribophorin I Ribosomal_L22 PF00237.19 KIK48914.1 - 1.5e-23 83.0 0.2 2.7e-23 82.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e CiPC PF15800.5 KIK48914.1 - 0.069 12.9 6.9 0.088 12.5 6.9 1.1 1 0 0 1 1 1 0 Clock interacting protein circadian Tom5 PF10642.9 KIK48914.1 - 2.4 8.2 5.5 1.8 8.6 1.8 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Yos1 PF08571.10 KIK48915.1 - 9e-33 112.4 0.1 1.1e-32 112.1 0.1 1.1 1 0 0 1 1 1 1 Yos1-like GILT PF03227.16 KIK48916.1 - 5.6e-16 58.7 0.7 9.1e-16 58.0 0.7 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Cid2 PF09774.9 KIK48917.1 - 3.9e-29 102.1 9.0 2.1e-28 99.8 9.0 1.8 1 1 0 1 1 1 1 Caffeine-induced death protein 2 zf-C2H2 PF00096.26 KIK48918.1 - 0.00027 21.2 0.4 0.00027 21.2 0.4 3.6 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK48918.1 - 0.00048 20.7 20.8 0.0055 17.4 0.4 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK48918.1 - 0.00097 19.5 15.0 0.0056 17.1 0.6 3.6 3 1 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 KIK48918.1 - 0.024 15.1 2.7 0.025 15.0 0.1 2.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIK48918.1 - 0.71 10.2 4.3 1.1 9.7 0.0 3.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Herpes_pp85 PF04637.12 KIK48919.1 - 0.11 10.9 5.9 0.14 10.5 5.9 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) RNR_inhib PF08591.10 KIK48920.1 - 0.00028 22.2 1.1 0.00053 21.3 1.1 1.6 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor Bromodomain PF00439.25 KIK48921.1 - 8.5e-23 80.2 0.3 8.5e-23 80.2 0.3 1.7 2 0 0 2 2 2 1 Bromodomain Myb_DNA-binding PF00249.31 KIK48921.1 - 0.067 13.4 0.0 0.26 11.5 0.0 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK48921.1 - 0.068 13.4 0.1 11 6.4 0.0 2.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain FAT PF02259.23 KIK48922.1 - 5.4e-68 229.7 8.3 5.4e-68 229.7 8.3 2.0 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KIK48922.1 - 3.4e-21 76.2 0.0 7e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Herpes_UL36 PF03586.13 KIK48922.1 - 0.028 13.7 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein DASH_Dad2 PF08654.10 KIK48922.1 - 0.13 12.7 0.1 0.72 10.3 0.1 2.3 1 0 0 1 1 1 0 DASH complex subunit Dad2 Corona_I PF03187.14 KIK48923.1 - 0.055 13.1 0.0 0.057 13.1 0.0 1.1 1 0 0 1 1 1 0 Corona nucleocapsid I protein WH2 PF02205.20 KIK48926.1 - 2.6e-06 27.1 2.0 1e-05 25.2 0.9 2.4 2 0 0 2 2 2 1 WH2 motif Thioredoxin PF00085.20 KIK48927.1 - 7.1e-61 202.6 0.1 1.4e-31 108.5 0.0 3.9 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 KIK48927.1 - 2.7e-38 131.7 0.0 3.2e-30 105.4 0.0 2.7 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KIK48927.1 - 2.5e-08 34.0 0.1 0.012 15.7 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KIK48927.1 - 3.6e-07 30.6 0.2 0.014 15.8 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KIK48927.1 - 1.1e-06 28.9 0.0 0.15 12.4 0.0 3.8 4 1 1 5 5 5 2 Thioredoxin-like AhpC-TSA PF00578.21 KIK48927.1 - 1.2e-06 28.4 0.2 0.06 13.3 0.0 3.3 3 1 0 3 3 3 2 AhpC/TSA family Calsequestrin PF01216.17 KIK48927.1 - 2.4e-05 23.6 0.0 6.3e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Calsequestrin Redoxin PF08534.10 KIK48927.1 - 0.00048 19.9 0.9 0.81 9.4 0.0 2.7 3 0 0 3 3 3 2 Redoxin OST3_OST6 PF04756.13 KIK48927.1 - 0.0066 15.8 0.1 0.48 9.7 0.0 2.2 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 KIK48927.1 - 0.15 12.2 0.0 0.74 9.9 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin domain TCTP PF00838.17 KIK48928.1 - 1.2e-70 237.1 1.6 1.4e-70 237.0 1.6 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Mus7 PF09462.10 KIK48928.1 - 0.14 10.9 0.0 0.16 10.8 0.0 1.0 1 0 0 1 1 1 0 Mus7/MMS22 family UTP15_C PF09384.10 KIK48929.1 - 8.1e-49 165.1 0.0 1.3e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KIK48929.1 - 3e-23 81.7 0.8 6.9e-05 23.5 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK48929.1 - 4.2e-08 33.4 0.0 0.032 14.5 0.0 4.3 3 3 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KIK48929.1 - 0.0013 17.3 0.1 0.008 14.8 0.1 2.1 2 1 1 3 3 3 1 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 KIK48929.1 - 0.0013 17.8 0.0 0.26 10.3 0.0 2.1 2 0 0 2 2 2 2 Coatomer WD associated region DUF5122 PF17164.4 KIK48929.1 - 0.098 13.0 0.1 0.27 11.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5122) beta-propeller CTNNBL PF08216.11 KIK48930.1 - 4.2e-34 116.8 0.0 1.1e-33 115.5 0.0 1.7 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Spore_III_AB PF09548.10 KIK48930.1 - 0.047 13.8 0.1 0.28 11.3 0.1 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Arm PF00514.23 KIK48930.1 - 0.1 12.7 0.6 0.69 10.0 0.0 2.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Exo70 PF03081.15 KIK48930.1 - 0.27 10.3 3.4 0.23 10.4 0.3 2.3 3 0 0 3 3 3 0 Exo70 exocyst complex subunit RRM_1 PF00076.22 KIK48931.1 - 6.1e-15 54.8 0.0 8.6e-15 54.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L5e PF17144.4 KIK48932.1 - 9.6e-82 272.8 0.0 1.5e-81 272.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KIK48932.1 - 5.2e-35 120.3 2.9 5.2e-35 120.3 2.9 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.6 KIK48932.1 - 0.14 12.4 0.2 12 6.2 0.0 2.7 2 1 0 2 2 2 0 Threonine synthase N terminus MtrA PF04208.14 KIK48932.1 - 0.2 11.3 0.0 0.44 10.2 0.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A Med17 PF10156.9 KIK48933.1 - 2.8e-39 135.1 0.0 8.2e-39 133.6 0.0 1.6 1 1 0 1 1 1 1 Subunit 17 of Mediator complex Fungal_trans PF04082.18 KIK48934.1 - 8.2e-17 61.1 0.1 1.4e-16 60.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIK48934.1 - 1.8e-05 24.8 9.8 1.8e-05 24.8 9.8 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GPI-anchored PF10342.9 KIK48935.1 - 2.6e-07 31.3 0.4 1.2e-06 29.2 0.4 1.9 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Snf7 PF03357.21 KIK48936.1 - 7.8e-29 100.5 21.6 1.5e-28 99.6 21.6 1.5 1 1 0 1 1 1 1 Snf7 LUC7 PF03194.15 KIK48936.1 - 2 8.0 13.5 0.026 14.2 3.4 2.1 1 1 1 2 2 2 0 LUC7 N_terminus VID27 PF08553.10 KIK48938.1 - 1e-172 574.1 1.5 1.3e-172 573.7 1.5 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KIK48938.1 - 3.2e-56 189.9 0.3 3.2e-56 189.9 0.3 3.7 2 1 1 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 KIK48938.1 - 1.2e-23 83.5 0.2 3.5e-23 82.0 0.2 1.9 1 0 0 1 1 1 1 VID27 PH-like domain SDA1 PF05285.12 KIK48938.1 - 0.12 11.7 7.7 0.3 10.5 7.7 1.6 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KIK48938.1 - 0.37 8.9 8.7 0.64 8.2 8.7 1.3 1 0 0 1 1 1 0 Nop14-like family Trypan_PARP PF05887.11 KIK48938.1 - 4.8 7.2 14.3 14 5.7 14.3 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RTA1 PF04479.13 KIK48940.1 - 5.4e-51 173.1 13.0 5.4e-51 173.1 13.0 1.5 2 0 0 2 2 2 1 RTA1 like protein STE3 PF02076.15 KIK48940.1 - 0.0019 17.5 3.0 0.0019 17.5 3.0 1.8 2 0 0 2 2 2 1 Pheromone A receptor Coiled-coil_56 PF09813.9 KIK48940.1 - 0.17 11.9 1.1 4.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 DUF2892 PF11127.8 KIK48940.1 - 0.76 9.9 5.5 0.24 11.5 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) RTA1 PF04479.13 KIK48941.1 - 9.1e-50 169.1 9.3 9.1e-50 169.1 9.3 1.4 2 0 0 2 2 2 1 RTA1 like protein ICMT PF04140.14 KIK48942.1 - 8.3e-15 55.0 0.3 2.6e-14 53.4 0.0 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIK48942.1 - 1.3e-09 38.4 5.8 2e-08 34.6 1.2 3.1 2 1 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIK48942.1 - 1.3e-06 27.4 0.1 2e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF3955 PF13127.6 KIK48942.1 - 9.2e-05 22.2 0.4 0.00026 20.7 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3955) DUF1295 PF06966.12 KIK48942.1 - 0.011 15.3 0.1 0.018 14.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Tetraspanin PF00335.20 KIK48942.1 - 0.013 15.2 0.8 0.048 13.4 0.2 2.0 1 1 1 2 2 2 0 Tetraspanin family Rpr2 PF04032.16 KIK48944.1 - 0.0082 16.4 0.2 0.0082 16.4 0.2 2.0 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain RNB PF00773.19 KIK48946.1 - 1.3e-100 336.9 0.2 2.8e-100 335.8 0.2 1.6 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 KIK48946.1 - 7.4e-25 87.1 0.1 2.3e-24 85.5 0.1 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 KIK48946.1 - 1.6e-23 82.5 0.0 3.7e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 KIK48946.1 - 0.00035 20.7 0.0 0.15 12.2 0.0 2.9 3 0 0 3 3 3 1 Cold shock domain Rrp44_S1 PF17215.3 KIK48946.1 - 0.0031 17.4 0.4 0.0086 16.0 0.0 1.9 2 0 0 2 2 2 1 S1 domain Rrp44_CSD1 PF17216.3 KIK48946.1 - 0.012 15.3 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Rrp44-like cold shock domain BAF1_ABF1 PF04684.13 KIK48946.1 - 7.1 5.6 12.1 0.77 8.7 0.3 2.6 3 0 0 3 3 3 0 BAF1 / ABF1 chromatin reorganising factor Iso_dh PF00180.20 KIK48947.1 - 1.3e-101 340.2 0.0 1.5e-101 340.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase TFIIS_C PF01096.18 KIK48948.1 - 1.1e-18 66.8 6.1 1.1e-18 66.8 6.1 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KIK48948.1 - 6e-09 35.6 0.9 6e-09 35.6 0.9 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 KIK48948.1 - 0.0019 18.2 10.1 0.014 15.3 0.3 2.3 2 1 0 2 2 2 2 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 KIK48948.1 - 0.019 14.9 11.8 16 5.6 0.3 4.2 4 0 0 4 4 4 0 PhnA Zinc-Ribbon DUF3716 PF12511.8 KIK48948.1 - 0.021 14.9 9.2 0.14 12.2 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) zf-ribbon_3 PF13248.6 KIK48948.1 - 0.031 13.7 3.1 5.9 6.4 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 KIK48948.1 - 0.2 11.7 10.0 2.6 8.1 0.4 2.5 2 1 0 2 2 2 0 Double zinc ribbon CpXC PF14353.6 KIK48948.1 - 1.3 9.1 6.6 19 5.3 0.7 2.4 1 1 1 2 2 2 0 CpXC protein zinc_ribbon_4 PF13717.6 KIK48948.1 - 2.5 8.1 11.3 7.9 6.5 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_10 PF10058.9 KIK48948.1 - 3.3 7.5 11.0 3.7 7.4 2.1 2.6 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Tnp_zf-ribbon_2 PF13842.6 KIK48948.1 - 3.4 8.5 12.1 2.7 8.9 2.0 3.4 3 1 1 4 4 4 0 DDE_Tnp_1-like zinc-ribbon zinc-ribbons_6 PF07191.12 KIK48948.1 - 3.7 7.6 10.5 0.61 10.1 0.9 2.5 1 1 0 2 2 2 0 zinc-ribbons CRCB PF02537.15 KIK48950.1 - 1.7e-30 105.2 20.0 9.3e-18 64.3 7.7 2.2 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) CK_II_beta PF01214.18 KIK48951.1 - 7e-74 247.6 0.0 1.1e-73 247.0 0.0 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit SDA1 PF05285.12 KIK48951.1 - 0.057 12.8 8.3 0.076 12.4 8.3 1.1 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 KIK48951.1 - 0.069 13.3 13.2 0.089 12.9 13.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.10 KIK48951.1 - 0.35 10.2 6.7 0.48 9.7 6.7 1.1 1 0 0 1 1 1 0 BUD22 DUF4746 PF15928.5 KIK48951.1 - 0.77 9.1 6.5 1.3 8.3 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Paf1 PF03985.13 KIK48951.1 - 3.4 6.6 11.1 4.8 6.1 11.1 1.1 1 0 0 1 1 1 0 Paf1 Ribosomal_L36e PF01158.18 KIK48952.1 - 4.7e-38 129.3 3.3 5.1e-38 129.2 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e TetR_C_9 PF14514.6 KIK48952.1 - 0.051 13.7 0.1 0.062 13.4 0.1 1.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain SNARE_assoc PF09335.11 KIK48953.1 - 1.2e-16 61.3 2.9 2.3e-16 60.4 2.9 1.5 1 0 0 1 1 1 1 SNARE associated Golgi protein PSI_PsaJ PF01701.18 KIK48953.1 - 1.4 9.5 8.4 4.4 7.9 0.0 3.6 3 0 0 3 3 3 0 Photosystem I reaction centre subunit IX / PsaJ Mito_carr PF00153.27 KIK48955.1 - 1.8e-61 204.1 3.2 1e-21 76.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KIK48955.1 - 7.1e-05 22.1 0.0 0.011 15.3 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KIK48955.1 - 0.00021 21.0 0.0 0.012 15.5 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KIK48955.1 - 0.0034 17.8 0.1 0.011 16.1 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KIK48955.1 - 0.011 15.2 1.0 0.054 13.0 0.1 2.3 2 0 0 2 2 2 0 EF hand Amidohydro_2 PF04909.14 KIK48956.1 - 8.2e-29 101.3 0.1 1e-28 101.0 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KIK48956.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 TatD related DNase Histidinol_dh PF00815.20 KIK48957.1 - 2.8e-165 550.3 0.3 3.7e-165 549.9 0.3 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KIK48957.1 - 1.4e-25 88.9 0.2 3.1e-25 87.8 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KIK48957.1 - 9.4e-14 51.6 0.5 9.4e-14 51.6 0.5 2.4 3 0 0 3 3 3 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG-like PF12643.7 KIK48957.1 - 0.0086 16.3 0.2 0.018 15.3 0.2 1.5 1 0 0 1 1 1 1 MazG-like family TPR_10 PF13374.6 KIK48958.1 - 5.7e-41 137.3 21.4 2.2e-05 24.1 0.1 14.3 13 3 0 13 13 13 9 Tetratricopeptide repeat CHAT PF12770.7 KIK48958.1 - 9.1e-33 113.9 0.1 2.7e-32 112.3 0.1 1.8 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 KIK48958.1 - 1.8e-20 73.0 16.0 0.013 15.7 0.1 11.5 11 2 1 12 12 12 5 Tetratricopeptide repeat TPR_7 PF13176.6 KIK48958.1 - 3.4e-11 42.4 14.2 5.7 7.2 0.0 11.4 11 2 0 11 11 11 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIK48958.1 - 2.8e-10 39.5 17.1 1.8 8.5 0.1 11.4 12 1 1 13 13 12 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIK48958.1 - 4.3e-08 33.3 15.7 6.2 7.9 0.0 10.1 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIK48958.1 - 2.9e-07 30.1 0.3 0.96 9.2 0.0 6.8 8 0 0 8 8 8 1 TPR repeat TPR_2 PF07719.17 KIK48958.1 - 1.2e-05 25.1 17.2 5.2 7.4 0.0 8.7 9 1 1 10 10 10 2 Tetratricopeptide repeat Sel1 PF08238.12 KIK48958.1 - 2.6e-05 24.8 0.0 2.4 8.9 0.0 5.2 5 0 0 5 5 3 2 Sel1 repeat MIT PF04212.18 KIK48958.1 - 0.0001 22.3 0.1 4.2 7.5 0.0 5.1 6 0 0 6 6 4 1 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 KIK48958.1 - 0.00044 20.3 2.7 43 4.7 0.1 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat EccE PF11203.8 KIK48958.1 - 0.0019 18.5 3.4 14 6.1 0.0 5.9 6 2 2 8 8 8 0 Putative type VII ESX secretion system translocon, EccE TPR_16 PF13432.6 KIK48958.1 - 0.0024 18.5 15.4 3.2 8.5 0.1 6.9 5 2 3 8 8 8 2 Tetratricopeptide repeat HGTP_anticodon PF03129.20 KIK48958.1 - 0.011 15.9 0.0 2.8e+02 1.7 0.0 6.6 8 0 0 8 8 8 0 Anticodon binding domain Surp PF01805.20 KIK48958.1 - 0.1 12.6 0.0 0.33 11.0 0.0 1.9 1 0 0 1 1 1 0 Surp module DUF2600 PF10776.9 KIK48958.1 - 0.15 10.9 0.1 0.96 8.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2600) Transket_pyr PF02779.24 KIK48959.1 - 8.7e-48 162.3 0.0 1.7e-47 161.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KIK48959.1 - 6.4e-42 142.3 0.2 1.2e-41 141.5 0.2 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KIK48959.1 - 0.0076 16.5 0.0 0.018 15.3 0.0 1.7 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II Iso_dh PF00180.20 KIK48960.1 - 1.7e-78 264.2 0.0 2.1e-78 263.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HABP4_PAI-RBP1 PF04774.15 KIK48962.1 - 0.01 16.7 0.3 0.033 15.0 0.3 1.8 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Gln-synt_C PF00120.24 KIK48964.1 - 3.8e-17 62.3 0.0 3.3e-15 56.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KIK48964.1 - 5.3e-08 32.5 0.0 9.1e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF4499 PF14934.6 KIK48965.1 - 0.069 13.5 0.1 0.084 13.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4499) DnaJ PF00226.31 KIK48966.1 - 1.9e-16 59.9 0.0 2.8e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain OAD_gamma PF04277.13 KIK48966.1 - 0.0012 19.4 1.4 7.5 7.2 0.1 3.3 3 0 0 3 3 3 2 Oxaloacetate decarboxylase, gamma chain zf-RRN7 PF11781.8 KIK48967.1 - 0.042 13.5 0.1 0.099 12.4 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF4569 PF15133.6 KIK48969.1 - 0.36 10.5 6.6 0.43 10.3 6.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DUF5383 PF17355.2 KIK48969.1 - 0.44 10.9 7.4 0.6 10.5 7.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5383) DUF4746 PF15928.5 KIK48969.1 - 1.3 8.4 8.6 1.5 8.2 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MAJIN PF15077.6 KIK48969.1 - 2 8.2 9.1 2.5 7.8 9.1 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein TMEM214 PF10151.9 KIK48969.1 - 5.1 5.4 7.6 6 5.2 7.6 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator RR_TM4-6 PF06459.12 KIK48969.1 - 5.5 6.7 12.0 6.8 6.4 12.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Histone PF00125.24 KIK48970.1 - 1.2e-42 145.3 10.6 1.6e-41 141.7 10.6 2.0 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KIK48970.1 - 0.00068 19.7 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KIK48970.1 - 0.0012 19.1 0.2 0.0023 18.3 0.2 1.4 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIK48970.1 - 0.016 15.5 1.2 0.02 15.2 0.2 1.6 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Syntaxin-6_N PF09177.11 KIK48971.1 - 0.082 13.5 0.3 18 6.0 0.0 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal TRAM_LAG1_CLN8 PF03798.16 KIK48972.1 - 4.8e-31 108.1 27.3 4.8e-31 108.1 27.3 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KIK48972.1 - 3.7e-19 68.1 0.6 9.2e-19 66.9 0.6 1.7 1 0 0 1 1 1 1 TRAM1-like protein RNase_T PF00929.24 KIK48973.1 - 6.5e-07 30.0 0.0 1.5e-06 28.9 0.0 1.7 1 1 0 1 1 1 1 Exonuclease EloA-BP1 PF15870.5 KIK48973.1 - 3.5e-06 27.4 0.0 7.2e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 ElonginA binding-protein 1 CHORD PF04968.12 KIK48973.1 - 0.0041 17.8 7.2 0.01 16.6 7.2 1.7 1 0 0 1 1 1 1 CHORD Clat_adaptor_s PF01217.20 KIK48974.1 - 5.2e-57 191.8 1.6 6e-57 191.6 1.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain 60KD_IMP PF02096.20 KIK48975.1 - 1.4e-13 51.1 0.9 3.9e-12 46.4 0.9 2.0 1 1 0 1 1 1 1 60Kd inner membrane protein WD40 PF00400.32 KIK48977.1 - 1.7e-12 47.7 3.5 6e-05 23.7 0.1 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK48977.1 - 2.1e-05 24.7 0.1 0.00098 19.4 0.1 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 KIK48978.1 - 3.6e-05 23.5 0.3 2.1 8.7 0.0 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK48978.1 - 0.0068 16.2 0.0 12 5.9 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3760 PF12586.8 KIK48978.1 - 0.018 15.2 0.1 0.045 13.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) TPR_20 PF14561.6 KIK48978.1 - 0.055 13.8 0.5 20 5.6 0.0 3.5 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIK48978.1 - 0.088 13.1 0.0 3.8 8.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KIK48978.1 - 0.19 12.2 1.8 2.6 8.5 0.0 2.7 2 1 1 3 3 3 0 Bacterial transcriptional activator domain WD40 PF00400.32 KIK48980.1 - 1.1e-33 114.7 7.9 2e-06 28.4 0.1 7.8 7 1 1 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK48980.1 - 4.2e-13 49.4 0.0 0.044 14.1 0.0 5.7 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK48980.1 - 6e-05 22.1 0.0 0.05 12.6 0.0 3.6 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK48980.1 - 0.0013 18.7 1.0 3.3 7.8 0.0 3.9 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat TPR_2 PF07719.17 KIK48980.1 - 0.0029 17.6 1.1 9.5 6.6 0.1 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIK48980.1 - 0.023 14.5 0.1 18 5.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 KIK48980.1 - 0.029 13.4 0.0 0.72 8.8 0.0 2.3 2 0 0 2 2 2 0 Coatomer WD associated region WD40 PF00400.32 KIK48984.1 - 2.9e-25 88.0 15.0 6.2e-05 23.7 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK48984.1 - 1.2e-10 41.5 0.4 0.055 13.8 0.1 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIK48984.1 - 0.067 11.8 0.2 4.9 5.7 0.0 2.3 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Tmemb_170 PF10190.9 KIK48988.1 - 5.2e-10 39.6 7.8 7.1e-08 32.8 4.2 2.1 2 0 0 2 2 2 2 Putative transmembrane protein 170 GATA PF00320.27 KIK48992.1 - 3.1e-16 58.7 3.4 6.1e-16 57.7 3.4 1.5 1 0 0 1 1 1 1 GATA zinc finger SUIM_assoc PF16619.5 KIK48992.1 - 0.011 15.8 4.1 0.011 15.8 4.1 2.6 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Dor1 PF04124.12 KIK48992.1 - 0.093 11.4 0.4 0.13 10.9 0.4 1.1 1 0 0 1 1 1 0 Dor1-like family TF_Zn_Ribbon PF08271.12 KIK48992.1 - 0.11 12.1 1.2 0.23 11.0 1.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding ArfGap PF01412.18 KIK48992.1 - 0.13 12.3 1.4 0.17 11.9 0.2 1.8 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Peptidase_S28 PF05577.12 KIK48993.1 - 3.9e-49 167.6 0.7 5.3e-48 163.9 0.7 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KIK48993.1 - 0.00086 18.8 0.4 0.0027 17.2 0.2 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S28 PF05577.12 KIK48995.1 - 2.1e-49 168.5 1.4 1.3e-48 166.0 1.4 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KIK48995.1 - 5.6e-05 22.7 0.3 0.00013 21.5 0.3 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family GST_C_5 PF16865.5 KIK48995.1 - 0.16 12.6 0.1 1.5 9.4 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Peptidase_S28 PF05577.12 KIK48996.1 - 3.8e-14 52.3 0.4 3.8e-14 52.3 0.4 1.4 2 0 0 2 2 2 1 Serine carboxypeptidase S28 SRCR PF00530.18 KIK48996.1 - 0.056 13.9 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain Peptidase_S28 PF05577.12 KIK48997.1 - 5e-34 117.8 0.1 7.6e-34 117.2 0.1 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S28 PF05577.12 KIK48998.1 - 5.5e-48 163.8 0.8 2e-33 115.8 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KIK48998.1 - 0.088 12.3 0.6 0.23 10.9 0.3 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Peptidase_S28 PF05577.12 KIK48999.1 - 1.3e-47 162.6 1.3 1.5e-46 159.1 1.3 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KIK48999.1 - 0.00029 20.4 0.5 0.0011 18.4 0.3 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family PTP_tm PF18861.1 KIK49000.1 - 0.053 13.5 0.4 0.072 13.1 0.4 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J UQ_con PF00179.26 KIK49001.1 - 1.8e-16 60.0 0.0 2.1e-16 59.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CSN7a_helixI PF18392.1 KIK49001.1 - 0.047 13.6 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain RWD PF05773.22 KIK49001.1 - 0.11 12.7 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 RWD domain VHS PF00790.19 KIK49002.1 - 1.5e-31 109.1 0.0 2.5e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 VHS domain SH3_2 PF07653.17 KIK49002.1 - 6e-14 51.5 0.1 1.3e-13 50.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIK49002.1 - 8.2e-14 50.9 0.0 1.6e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIK49002.1 - 8.9e-14 51.1 0.1 2e-13 50.0 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KIK49002.1 - 2.7e-12 46.8 2.1 5.4e-12 45.9 2.1 1.5 1 0 0 1 1 1 1 GAT domain UIM PF02809.20 KIK49002.1 - 0.034 14.0 3.6 0.099 12.6 3.6 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Hrs_helical PF12210.8 KIK49002.1 - 0.098 13.2 0.8 0.23 12.0 0.8 1.6 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate zf-C2H2_jaz PF12171.8 KIK49003.1 - 2.4e-10 40.4 3.0 4.4e-10 39.6 3.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIK49003.1 - 0.011 16.2 2.2 0.024 15.0 2.2 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KIK49003.1 - 0.013 15.8 0.2 0.013 15.8 0.2 1.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KIK49003.1 - 0.13 13.2 0.8 0.13 13.2 0.8 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger Pro_isomerase PF00160.21 KIK49004.1 - 4.9e-43 147.1 0.0 6.1e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MYO10_CC PF16735.5 KIK49005.1 - 0.04 14.0 2.8 0.091 12.9 2.8 1.6 1 0 0 1 1 1 0 Unconventional myosin-X coiled coil domain Thymidylate_kin PF02223.17 KIK49006.1 - 1.9e-28 99.4 0.0 2.1e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase UQ_con PF00179.26 KIK49007.1 - 9.6e-18 64.2 0.0 1.5e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PilS PF08805.11 KIK49009.1 - 0.043 13.7 0.2 0.38 10.6 0.1 2.6 3 0 0 3 3 3 0 PilS N terminal RhoGEF PF00621.20 KIK49011.1 - 1.3e-29 103.7 0.0 1.8e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 KIK49011.1 - 8.2e-15 54.7 6.0 1.1e-11 44.7 2.7 2.4 2 0 0 2 2 2 2 FYVE zinc finger Glyco_hydro_12 PF01670.16 KIK49012.1 - 3.3e-34 118.8 8.5 3.8e-34 118.6 8.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Gelsolin PF00626.22 KIK49012.1 - 0.16 11.9 0.6 11 6.0 0.0 2.3 2 0 0 2 2 2 0 Gelsolin repeat HLH PF00010.26 KIK49013.1 - 0.00018 21.4 0.6 0.00031 20.6 0.6 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MIP-T3_C PF17749.1 KIK49013.1 - 0.078 12.9 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Elf4 PF07011.11 KIK49013.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Early Flowering 4 domain Glyco_hydro_12 PF01670.16 KIK49015.1 - 6.9e-36 124.2 14.1 8.3e-36 124.0 14.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 GST_N_3 PF13417.6 KIK49016.1 - 3.7e-14 52.9 0.1 1.2e-13 51.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIK49016.1 - 9.1e-12 45.1 0.3 9.4e-10 38.7 0.1 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIK49016.1 - 2e-05 24.6 0.0 3.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KIK49016.1 - 0.00079 20.1 0.0 0.0014 19.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N PF02798.20 KIK49016.1 - 0.038 14.3 0.2 0.62 10.5 0.0 2.5 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIK49016.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain WD40 PF00400.32 KIK49017.1 - 6.7e-62 204.0 34.2 5.8e-10 39.6 0.4 8.9 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK49017.1 - 6.2e-24 84.1 1.0 5.6e-06 26.6 0.0 6.0 2 2 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 KIK49017.1 - 2.8e-08 34.1 0.0 5.4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 KIK49017.1 - 1.5e-07 30.4 0.4 0.083 11.5 0.0 4.3 5 0 0 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK49017.1 - 1.2e-06 27.8 0.0 0.018 14.1 0.0 3.7 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIK49017.1 - 0.033 14.1 0.2 4.3 7.4 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 KIK49017.1 - 0.052 11.5 0.0 0.1 10.6 0.0 1.4 1 0 0 1 1 1 0 IKI3 family Nucleoporin_N PF08801.11 KIK49017.1 - 0.058 12.1 0.0 1.8 7.2 0.0 2.9 4 0 0 4 4 4 0 Nup133 N terminal like PQQ_3 PF13570.6 KIK49017.1 - 0.16 12.5 1.4 5.6 7.6 1.1 3.5 3 0 0 3 3 3 0 PQQ-like domain Sec20 PF03908.13 KIK49021.1 - 4.9e-15 55.2 2.6 4.9e-15 55.2 2.6 2.0 2 0 0 2 2 2 1 Sec20 DUF429 PF04250.13 KIK49021.1 - 0.0072 16.1 1.7 0.013 15.3 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF429) Baculo_11_kDa PF06143.11 KIK49021.1 - 0.16 11.6 0.2 0.44 10.2 0.2 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family NPV_P10 PF05531.12 KIK49021.1 - 1.6 9.2 4.6 6.5 7.3 0.2 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AurF PF11583.8 KIK49024.1 - 0.075 12.3 0.0 0.087 12.1 0.0 1.0 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF MFS_1 PF07690.16 KIK49025.1 - 3.9e-35 121.4 34.9 3.9e-35 121.4 34.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily LptF_LptG PF03739.14 KIK49025.1 - 0.0067 15.3 8.2 0.084 11.7 0.5 2.6 2 0 0 2 2 2 2 Lipopolysaccharide export system permease LptF/LptG Lactamase_B PF00753.27 KIK49026.1 - 4.7e-07 30.0 0.0 6.9e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIK49026.1 - 0.007 15.9 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MFS_1 PF07690.16 KIK49027.1 - 2.1e-33 115.7 28.2 2.1e-33 115.7 28.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KIK49028.1 - 9.2e-34 116.9 30.5 9.2e-34 116.9 30.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KIK49028.1 - 0.19 11.5 5.0 0.71 9.6 1.3 2.5 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MFS_1 PF07690.16 KIK49030.1 - 1e-33 116.8 31.8 1e-33 116.8 31.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KIK49030.1 - 0.049 13.4 7.5 1 9.1 3.1 2.5 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MASE2 PF05230.11 KIK49032.1 - 0.011 15.8 1.1 0.027 14.5 1.1 1.7 1 0 0 1 1 1 0 MASE2 domain DUF2207 PF09972.9 KIK49032.1 - 0.94 8.2 5.1 1.5 7.5 5.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Biotin_carb_N PF00289.22 KIK49036.1 - 0.017 15.7 0.0 0.024 15.2 0.0 1.3 1 0 0 1 1 1 0 Biotin carboxylase, N-terminal domain ANAPC16 PF17256.2 KIK49037.1 - 0.021 15.2 0.0 0.047 14.1 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 16 PH PF00169.29 KIK49038.1 - 0.0043 17.5 0.0 0.11 13.1 0.0 2.6 3 0 0 3 3 3 1 PH domain DUF1929 PF09118.11 KIK49038.1 - 0.011 16.0 0.2 0.063 13.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1929) Plavaka PF18759.1 KIK49039.1 - 3.5e-38 131.7 0.0 5.6e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase DUF202 PF02656.15 KIK49041.1 - 0.07 13.6 0.8 0.16 12.5 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF202) TrbC PF04956.13 KIK49041.1 - 0.072 13.3 0.7 0.16 12.2 0.7 1.5 1 0 0 1 1 1 0 TrbC/VIRB2 family MKT1_C PF12246.8 KIK49043.1 - 1.2e-22 80.4 0.0 1.9e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KIK49043.1 - 3.3e-20 72.2 0.5 9.8e-18 64.3 0.5 2.5 1 1 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 KIK49043.1 - 7.7e-08 32.7 0.0 2.1e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KIK49043.1 - 0.0042 17.4 0.0 0.011 16.1 0.0 1.7 2 0 0 2 2 2 1 XPG I-region zf-C2H2 PF00096.26 KIK49045.1 - 0.00045 20.5 0.6 0.00045 20.5 0.6 1.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-met PF12874.7 KIK49045.1 - 0.0017 18.7 0.1 0.0041 17.4 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KIK49045.1 - 0.043 14.6 0.5 0.043 14.6 0.5 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIK49045.1 - 0.046 14.0 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Sec6 PF06046.13 KIK49045.1 - 0.1 11.0 0.2 0.15 10.4 0.2 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec6 O-FucT PF10250.9 KIK49046.1 - 1.4e-11 44.7 0.0 2.4e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Pirin PF02678.16 KIK49048.1 - 1.4e-24 86.1 1.5 2.2e-24 85.5 1.5 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 KIK49048.1 - 2.8e-07 30.1 0.3 1.6e-05 24.6 0.3 2.5 2 0 0 2 2 2 1 Cupin domain Pirin_C_2 PF17954.1 KIK49048.1 - 0.00015 21.9 0.0 0.0038 17.4 0.0 2.8 2 1 0 2 2 2 1 Quercetinase C-terminal cupin domain MMR_HSR1 PF01926.23 KIK49050.1 - 1.3e-14 54.2 0.0 1.8e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIK49050.1 - 1.3e-05 24.6 0.0 1.7e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIK49050.1 - 0.00017 21.7 0.1 0.0041 17.2 0.2 2.2 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KIK49050.1 - 0.0086 16.0 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase LYTB PF02401.18 KIK49050.1 - 0.03 13.6 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 LytB protein FeoB_N PF02421.18 KIK49050.1 - 0.041 13.4 0.0 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B ATPase_2 PF01637.18 KIK49050.1 - 0.047 13.6 0.2 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea WD40 PF00400.32 KIK49051.1 - 1.5e-60 199.7 21.9 3.3e-09 37.2 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK49051.1 - 3.1e-20 72.3 2.8 0.00013 22.1 0.1 6.0 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK49051.1 - 1.1e-10 41.7 0.3 0.0002 21.3 0.0 3.5 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIK49051.1 - 8.3e-08 31.3 9.1 0.012 14.3 0.2 5.1 1 1 4 6 6 6 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIK49051.1 - 2.2e-07 30.1 8.4 0.034 13.1 0.6 4.5 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIK49051.1 - 5.6e-05 22.6 0.1 0.02 14.3 0.0 2.7 2 1 1 3 3 3 2 WD40-like domain CDtoxinA PF03498.14 KIK49051.1 - 8.2e-05 22.2 1.1 0.0035 16.9 0.2 2.7 1 1 1 3 3 3 1 Cytolethal distending toxin A/C domain PALB2_WD40 PF16756.5 KIK49051.1 - 0.0034 16.4 5.7 0.85 8.5 0.1 4.3 1 1 3 5 5 5 2 Partner and localizer of BRCA2 WD40 domain RicinB_lectin_2 PF14200.6 KIK49051.1 - 0.027 15.2 0.9 1.8 9.4 0.0 3.4 2 1 2 4 4 4 0 Ricin-type beta-trefoil lectin domain-like SBD PF17882.1 KIK49051.1 - 0.045 13.6 0.3 5.6 6.8 0.0 2.4 2 0 0 2 2 2 0 OAA-family lectin sugar binding domain PRIMA1 PF16101.5 KIK49051.1 - 8.7 6.4 6.8 15 5.6 6.8 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 RabGAP-TBC PF00566.18 KIK49052.1 - 1.9e-45 155.2 0.0 2.9e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.6 KIK49052.1 - 3.3e-07 30.7 0.2 0.00025 21.4 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KIK49052.1 - 1.2e-05 24.5 0.6 0.0007 19.0 0.1 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KIK49052.1 - 1.3e-05 24.7 4.7 0.00082 19.1 0.3 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 KIK49052.1 - 7.1e-05 22.6 0.7 0.14 12.0 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair GRAM PF02893.20 KIK49052.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 GRAM domain EF-hand_5 PF13202.6 KIK49052.1 - 0.063 12.8 0.2 0.27 10.8 0.0 2.2 2 0 0 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.9 KIK49052.1 - 0.17 12.2 0.1 0.42 10.9 0.1 1.6 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region PX PF00787.24 KIK49054.1 - 2.6e-14 53.2 0.0 8.7e-14 51.5 0.0 1.7 2 0 0 2 2 2 1 PX domain WD40 PF00400.32 KIK49055.1 - 2.1e-27 94.8 16.5 5.8e-07 30.1 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK49055.1 - 1.3e-13 51.0 0.2 0.11 12.8 0.0 5.6 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIK49055.1 - 0.00013 21.9 0.0 0.38 10.6 0.0 3.2 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIK49055.1 - 0.00029 19.9 0.2 0.03 13.3 0.0 3.0 2 2 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_14 PF13428.6 KIK49055.1 - 0.011 16.5 0.5 16 6.6 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK49055.1 - 0.012 16.1 0.6 7.9 7.1 0.1 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIK49055.1 - 0.014 15.4 2.5 4.2 7.7 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat PD40 PF07676.12 KIK49055.1 - 0.016 15.2 0.0 19 5.4 0.0 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat BTAD PF03704.17 KIK49055.1 - 0.033 14.6 0.4 0.14 12.6 0.3 1.9 2 0 0 2 2 2 0 Bacterial transcriptional activator domain WD40 PF00400.32 KIK49056.1 - 6e-34 115.5 9.6 4e-07 30.6 0.0 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK49056.1 - 6.6e-11 42.4 0.5 0.013 15.8 0.0 5.5 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 KIK49056.1 - 2.4e-10 40.9 3.1 9.7e-08 32.5 0.2 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_2 PF07719.17 KIK49056.1 - 3.4e-05 23.6 11.7 1.5 9.1 0.2 7.2 8 0 0 8 8 8 3 Tetratricopeptide repeat Ge1_WD40 PF16529.5 KIK49056.1 - 5.8e-05 22.2 0.0 0.039 12.9 0.0 3.0 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein MIT PF04212.18 KIK49056.1 - 0.05 13.7 1.4 35 4.6 0.1 3.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 KIK49056.1 - 0.27 11.1 15.0 7 6.6 0.8 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat ABC_tran PF00005.27 KIK49058.1 - 1.5e-25 90.3 0.0 2.8e-25 89.4 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_15 PF13175.6 KIK49058.1 - 6.7e-10 39.2 0.1 4.7e-05 23.3 0.5 2.1 1 1 1 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KIK49058.1 - 2.2e-08 34.3 3.6 0.0015 18.4 0.4 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIK49058.1 - 5.2e-06 26.1 0.0 0.039 13.4 0.4 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain G-alpha PF00503.20 KIK49058.1 - 0.0007 18.9 0.0 0.00082 18.6 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit AAA_29 PF13555.6 KIK49058.1 - 0.00077 19.2 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KIK49058.1 - 0.0016 19.0 0.0 0.0029 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 KIK49058.1 - 0.0023 18.1 0.0 0.0041 17.3 0.0 1.4 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 KIK49058.1 - 0.0078 16.2 0.0 0.05 13.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIK49058.1 - 0.009 16.4 0.1 0.015 15.7 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_27 PF13514.6 KIK49058.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIK49058.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIK49058.1 - 0.023 15.2 0.0 0.15 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KIK49058.1 - 0.029 13.7 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 KIK49058.1 - 0.04 14.2 0.0 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain KGG PF10685.9 KIK49058.1 - 0.18 12.1 0.1 0.44 10.9 0.1 1.7 1 0 0 1 1 1 0 Stress-induced bacterial acidophilic repeat motif cobW PF02492.19 KIK49058.1 - 0.22 11.1 0.9 9.9 5.7 0.5 2.1 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dimer_Tnp_hAT PF05699.14 KIK49060.1 - 9.7e-21 73.4 0.6 1.2e-20 73.0 0.6 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region LPD37 PF18853.1 KIK49061.1 - 0.16 11.5 0.0 0.16 11.5 0.0 1.0 1 0 0 1 1 1 0 Large polyvalent protein associated domain 37 O-FucT PF10250.9 KIK49062.1 - 1.9e-11 44.2 0.0 3.1e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase TRAM1 PF08390.11 KIK49064.1 - 0.0033 17.0 0.3 0.012 15.2 0.3 2.0 1 1 0 1 1 1 1 TRAM1-like protein Acetyltransf_1 PF00583.25 KIK49065.1 - 1.8e-05 24.9 0.0 3.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIK49065.1 - 3.9e-05 23.6 0.0 6.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIK49065.1 - 0.0014 19.0 0.0 0.0023 18.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK49065.1 - 0.09 12.8 0.0 0.23 11.5 0.0 1.6 2 0 0 2 2 2 0 FR47-like protein DUF2015 PF09435.10 KIK49066.1 - 2.9e-32 110.8 0.0 3.4e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) DUF1771 PF08590.10 KIK49067.1 - 0.015 15.7 0.4 0.015 15.7 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) Bacillus_HBL PF05791.11 KIK49070.1 - 0.019 14.8 0.7 0.093 12.5 0.5 2.1 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Chromo_shadow PF01393.19 KIK49071.1 - 2.1e-16 59.8 0.4 2e-14 53.4 0.1 2.4 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 KIK49071.1 - 1.1e-09 38.1 1.9 3.1e-09 36.6 1.0 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RNA_pol_Rpc4 PF05132.14 KIK49071.1 - 2.1 8.7 15.0 0.69 10.3 5.4 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 CCDC53 PF10152.9 KIK49071.1 - 2.5 8.5 10.3 1.6 9.1 2.6 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex RRM_1 PF00076.22 KIK49072.1 - 1e-14 54.1 0.0 1.6e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIK49072.1 - 0.069 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif zf-MYND PF01753.18 KIK49073.1 - 2.9e-07 30.5 15.6 6.2e-07 29.4 15.6 1.6 1 0 0 1 1 1 1 MYND finger DUF3846 PF12957.7 KIK49073.1 - 0.19 12.1 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) ECR1_N PF14382.6 KIK49074.1 - 1.6e-15 56.6 0.2 2.8e-15 55.8 0.2 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KIK49074.1 - 1.5e-14 54.1 0.1 2.7e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 KIK49074.1 - 0.042 14.5 0.5 0.76 10.4 0.1 2.6 2 1 1 3 3 3 0 Exosome component EXOSC1/CSL4 DUF3295 PF11702.8 KIK49075.1 - 0.0014 18.1 4.6 0.0016 17.9 4.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) Cwf_Cwc_15 PF04889.12 KIK49075.1 - 0.17 11.6 10.4 0.21 11.3 10.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4770 PF15994.5 KIK49075.1 - 0.22 11.7 1.6 0.33 11.2 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) TERB2 PF15101.6 KIK49075.1 - 0.23 11.5 3.8 0.34 10.9 3.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF5580 PF17743.1 KIK49075.1 - 0.55 8.7 4.6 0.68 8.4 4.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Pox_Ag35 PF03286.14 KIK49075.1 - 1.2 8.9 9.9 1.9 8.2 9.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4746 PF15928.5 KIK49075.1 - 5 6.5 9.9 6.5 6.1 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) FYDLN_acid PF09538.10 KIK49075.1 - 8.9 7.1 16.1 15 6.3 16.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RINGv PF12906.7 KIK49077.1 - 7.9e-16 57.9 7.0 1.4e-15 57.2 7.0 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KIK49077.1 - 0.0075 16.6 8.7 0.013 15.9 8.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 KIK49077.1 - 0.1 12.4 7.9 0.19 11.6 7.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KIK49077.1 - 0.47 10.5 4.0 0.89 9.7 4.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KIK49077.1 - 1 9.3 5.6 1.8 8.5 5.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KIK49077.1 - 1.2 9.4 4.9 2.4 8.4 4.9 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-rbx1 PF12678.7 KIK49077.1 - 4.1 7.8 6.5 7.8 6.9 6.5 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain C1_2 PF03107.16 KIK49077.1 - 9.5 6.6 9.6 14 6.1 2.9 2.3 1 1 1 2 2 2 0 C1 domain zf-C3HC4_2 PF13923.6 KIK49079.1 - 6e-08 32.4 2.3 6e-08 32.4 2.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK49079.1 - 2.3e-07 30.7 1.4 2.3e-07 30.7 1.4 1.7 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIK49079.1 - 2.8e-06 27.2 4.7 5.3e-06 26.3 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KIK49079.1 - 3.8e-06 26.7 5.1 1e-05 25.3 5.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK49079.1 - 4.4e-06 26.4 9.7 2.9e-05 23.8 9.7 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIK49079.1 - 8.7e-06 25.8 2.9 8.7e-06 25.8 2.9 1.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KIK49079.1 - 2.5e-05 24.5 12.7 0.0002 21.6 12.7 2.1 1 1 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KIK49079.1 - 0.0012 18.6 2.3 0.0012 18.6 2.3 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KIK49079.1 - 0.0019 18.0 0.4 0.0033 17.2 0.4 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 KIK49079.1 - 0.0073 15.9 0.8 0.0073 15.9 0.8 1.7 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type LMBR1 PF04791.16 KIK49079.1 - 0.015 14.2 0.4 0.019 13.9 0.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-rbx1 PF12678.7 KIK49079.1 - 0.02 15.2 4.9 0.058 13.7 4.9 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KIK49079.1 - 0.025 14.7 3.0 0.062 13.5 3.0 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Spc7 PF08317.11 KIK49079.1 - 0.085 11.7 8.7 0.12 11.3 8.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF812 PF05667.11 KIK49079.1 - 0.088 11.7 11.9 0.12 11.3 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) NSP16 PF06460.12 KIK49079.1 - 0.17 11.0 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NSP16 TMPIT PF07851.13 KIK49079.1 - 0.25 10.5 7.8 0.42 9.8 7.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein AAA_13 PF13166.6 KIK49079.1 - 0.34 9.5 9.5 0.46 9.1 9.5 1.1 1 0 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.8 KIK49079.1 - 1 9.4 16.3 3.5 7.7 16.3 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Cytochrome_C554 PF13435.6 KIK49079.1 - 1.4 9.9 5.6 5 8.1 5.6 1.9 1 0 0 1 1 1 0 Cytochrome c554 and c-prime ATG16 PF08614.11 KIK49079.1 - 5.2 7.2 22.6 0.08 13.2 14.5 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Cu-oxidase PF00394.22 KIK49080.1 - 3e-44 151.0 0.3 3e-42 144.4 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIK49080.1 - 4.5e-41 139.6 0.9 6.9e-36 122.9 0.1 3.5 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIK49080.1 - 4.4e-34 117.2 10.8 2.7e-33 114.6 1.2 3.5 3 1 0 3 3 3 2 Multicopper oxidase Lectin_like PF18560.1 KIK49080.1 - 0.18 11.9 0.0 26 4.9 0.0 2.3 2 0 0 2 2 2 0 Lectin like domain WD40 PF00400.32 KIK49083.1 - 1.4e-24 85.9 0.4 2.1e-08 34.7 0.0 4.3 3 1 1 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK49083.1 - 6e-11 42.5 0.0 0.0058 16.9 0.0 4.0 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIK49083.1 - 0.0054 15.7 0.0 0.14 11.1 0.0 2.2 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KIK49083.1 - 0.052 12.3 0.0 1.3 7.7 0.0 2.1 1 1 1 2 2 2 0 Nup133 N terminal like eIF2A PF08662.11 KIK49083.1 - 0.084 12.7 0.0 0.28 11.0 0.0 1.7 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A MFS_1 PF07690.16 KIK49088.1 - 2e-30 105.9 31.4 2e-30 105.9 31.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Use1 PF09753.9 KIK49088.1 - 0.031 14.0 0.2 0.051 13.3 0.2 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 PTS_2-RNA PF01885.16 KIK49089.1 - 7.3e-64 215.1 0.0 1.2e-63 214.5 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF2183 PF09949.9 KIK49090.1 - 1.4e-29 102.4 0.0 6.6e-29 100.2 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) Acid_phosphat_B PF03767.14 KIK49090.1 - 0.25 10.9 0.2 0.84 9.2 0.2 1.7 1 1 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DEAD PF00270.29 KIK49092.1 - 2.2e-45 154.5 0.0 4e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK49092.1 - 2.7e-31 108.2 0.0 1e-30 106.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KIK49092.1 - 0.039 13.2 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KIK49092.1 - 0.097 12.7 0.0 0.26 11.3 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.6 KIK49092.1 - 0.27 10.6 0.0 0.69 9.2 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF2379 PF09543.10 KIK49093.1 - 0.081 13.1 2.0 0.17 12.0 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) GATA PF00320.27 KIK49094.1 - 0.00049 19.7 1.2 0.001 18.6 1.2 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF383 PF04063.14 KIK49096.1 - 1.3e-61 207.6 0.0 2.9e-61 206.5 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KIK49096.1 - 2e-20 72.4 0.2 3.6e-20 71.6 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Spt20 PF12090.8 KIK49097.1 - 7.1e-24 84.7 0.3 2.4e-12 47.0 0.0 7.7 3 3 2 5 5 5 2 Spt20 family WD40 PF00400.32 KIK49098.1 - 1.1e-21 76.7 15.2 0.00015 22.5 0.1 8.5 9 0 0 9 9 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK49098.1 - 2.8e-12 46.8 0.2 0.00054 20.2 0.0 5.3 1 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 KIK49098.1 - 3.1e-12 47.1 4.0 5.2e-10 39.8 0.5 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_1 PF00515.28 KIK49098.1 - 0.00039 20.1 3.0 2.2 8.2 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIK49098.1 - 0.00053 19.9 4.2 5.7 7.3 0.0 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat Gmad1 PF10647.9 KIK49098.1 - 0.0032 17.3 1.2 0.059 13.1 0.1 3.0 2 2 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain TPR_19 PF14559.6 KIK49098.1 - 0.0068 16.9 2.9 1.3 9.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Cytochrom_D1 PF02239.16 KIK49098.1 - 0.019 13.5 0.0 0.054 12.0 0.0 1.7 1 1 1 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 KIK49098.1 - 0.058 13.4 8.1 27 4.9 0.0 6.1 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat TPR_6 PF13174.6 KIK49098.1 - 0.061 14.0 0.1 40 5.2 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KIK49098.1 - 0.061 12.8 0.7 3.5 7.2 0.1 3.2 3 0 0 3 3 3 0 SHNi-TPR TPR_16 PF13432.6 KIK49098.1 - 0.066 13.9 6.6 4.5 8.0 0.1 4.4 3 2 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 KIK49098.1 - 0.11 12.5 0.7 5.6 7.1 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 KIK49098.1 - 0.16 12.1 0.0 13 5.9 0.0 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 KIK49098.1 - 0.37 11.0 1.4 1.7 9.0 0.7 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 AICARFT_IMPCHas PF01808.18 KIK49099.1 - 7.7e-90 301.3 0.0 9.8e-90 301.0 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KIK49099.1 - 1e-24 86.5 0.0 1.9e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain DLH PF01738.18 KIK49100.1 - 0.00026 20.6 0.0 0.00043 19.9 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family DLH PF01738.18 KIK49101.1 - 1.6e-22 80.1 0.0 1.8e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DLH PF01738.18 KIK49102.1 - 3.8e-23 82.2 0.0 4.3e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KIK49102.1 - 0.024 14.3 0.1 0.14 11.7 0.1 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold PGA_cap PF09587.10 KIK49102.1 - 0.041 13.3 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Sds3 PF08598.11 KIK49103.1 - 1.7e-09 38.0 0.0 2.3e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Sds3-like HD_3 PF13023.6 KIK49104.1 - 3.2e-40 137.7 0.8 3.9e-40 137.5 0.8 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KIK49104.1 - 1.5e-09 37.9 1.2 2.8e-09 37.0 1.2 1.4 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KIK49104.1 - 1.5e-05 25.2 0.1 3.1e-05 24.2 0.1 1.6 1 1 0 1 1 1 1 HD domain MFS_1 PF07690.16 KIK49107.1 - 1.8e-29 102.8 35.8 3.1e-29 102.0 27.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2985 PF11204.8 KIK49107.1 - 0.012 15.7 0.3 0.012 15.7 0.3 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2985) RTC4 PF14474.6 KIK49108.1 - 2e-25 89.3 0.0 4.7e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 RTC4-like domain F-box PF00646.33 KIK49109.1 - 3.1e-05 23.7 0.6 6.7e-05 22.7 0.6 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIK49109.1 - 0.0003 20.6 0.8 0.0003 20.6 0.8 2.1 2 0 0 2 2 2 1 F-box-like Flavin_Reduct PF01613.18 KIK49110.1 - 3.4e-34 118.1 0.1 4.6e-34 117.7 0.1 1.2 1 0 0 1 1 1 1 Flavin reductase like domain DUF3218 PF11508.8 KIK49112.1 - 0.018 14.5 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3218) adh_short_C2 PF13561.6 KIK49113.1 - 0.027 14.0 0.1 0.039 13.5 0.1 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase zf-DNL PF05180.12 KIK49114.1 - 6.7e-31 106.0 0.1 7.9e-31 105.8 0.1 1.1 1 0 0 1 1 1 1 DNL zinc finger MFS_1 PF07690.16 KIK49115.1 - 9.8e-34 116.8 34.2 2.9e-32 112.0 25.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIK49115.1 - 6.2e-05 21.6 3.3 6.2e-05 21.6 3.3 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Cyclin_C PF02984.19 KIK49117.1 - 0.0092 16.1 0.0 0.031 14.4 0.0 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain SIR2 PF02146.17 KIK49119.1 - 5.1e-61 205.7 0.0 2.3e-60 203.5 0.0 2.1 2 0 0 2 2 2 1 Sir2 family DUF592 PF04574.13 KIK49119.1 - 2.3e-08 33.9 0.4 6.3e-07 29.3 0.2 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 KIK49119.1 - 0.0015 18.2 0.1 1 9.1 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Kei1 PF08552.11 KIK49120.1 - 2.5e-52 177.5 7.4 3.4e-52 177.1 7.4 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 FUSC PF04632.12 KIK49120.1 - 2.5 6.5 6.4 5.1 5.5 0.7 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family Histone PF00125.24 KIK49122.1 - 5.8e-49 165.8 2.2 6.5e-49 165.6 2.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KIK49122.1 - 2.8e-05 24.4 0.1 4.3e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KIK49122.1 - 6.3e-05 23.1 0.1 0.0001 22.3 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KIK49122.1 - 0.00086 19.5 0.1 0.0015 18.8 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 KIK49122.1 - 0.0046 17.5 1.9 0.0059 17.2 1.9 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Bromo_TP PF07524.13 KIK49122.1 - 0.096 12.7 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 KIK49123.1 - 4.2e-50 169.5 4.1 4.7e-50 169.3 4.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KIK49123.1 - 2.5e-05 24.6 0.1 4.2e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KIK49123.1 - 9.1e-05 22.5 1.1 0.0001 22.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KIK49123.1 - 0.00013 22.5 2.4 0.00017 22.2 2.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KIK49123.1 - 0.0013 18.9 1.3 0.0014 18.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 KIK49123.1 - 0.089 12.8 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 KIK49124.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIK49124.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIK49124.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIK49124.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK49124.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIK49124.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit WD40 PF00400.32 KIK49125.1 - 4.9e-35 119.0 5.1 6.2e-05 23.7 0.2 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK49125.1 - 2.4e-13 50.2 0.0 0.093 13.0 0.0 5.7 2 1 2 6 6 5 5 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 KIK49125.1 - 2.6e-07 30.3 10.9 0.041 14.0 0.1 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat HET PF06985.11 KIK49125.1 - 3.8e-07 30.5 6.1 1.8e-06 28.4 0.6 2.6 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF3808 PF10300.9 KIK49125.1 - 0.00087 18.1 0.6 1.7 7.3 0.3 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3808) TPR_1 PF00515.28 KIK49125.1 - 0.0027 17.5 11.4 0.14 12.0 0.1 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat Ge1_WD40 PF16529.5 KIK49125.1 - 0.017 14.1 0.0 3.2 6.6 0.0 3.2 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KIK49125.1 - 0.062 12.2 0.1 3.4 6.5 0.0 2.4 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain MIT PF04212.18 KIK49125.1 - 0.077 13.1 2.3 2.7 8.1 0.2 3.4 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 KIK49125.1 - 0.12 12.1 0.1 0.12 12.1 0.1 3.5 5 0 0 5 5 5 0 TPR repeat PD40 PF07676.12 KIK49125.1 - 0.13 12.2 0.0 6.9 6.7 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF3856 PF12968.7 KIK49125.1 - 0.25 11.4 1.1 28 4.8 0.0 3.9 4 1 0 5 5 5 0 Domain of Unknown Function (DUF3856) TPR_3 PF07720.12 KIK49125.1 - 0.51 10.4 3.8 24 5.1 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIK49125.1 - 2 9.0 8.0 18 6.0 0.2 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIK49125.1 - 4 8.2 12.5 0.69 10.6 0.1 4.5 5 1 0 5 5 4 0 Tetratricopeptide repeat Pkinase_fungal PF17667.1 KIK49126.1 - 1.3e-16 60.5 0.2 1.4e-12 47.1 0.1 2.1 1 1 1 2 2 2 2 Fungal protein kinase Tubulin-binding PF00418.19 KIK49127.1 - 0.085 12.9 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat Nucleopor_Nup85 PF07575.13 KIK49131.1 - 1.3e-58 198.9 0.0 1.3e-37 129.6 0.0 2.0 2 0 0 2 2 2 2 Nup85 Nucleoporin Viral_DNA_bi PF02236.17 KIK49131.1 - 0.11 12.7 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Viral DNA-binding protein, all alpha domain Trefoil PF00088.18 KIK49132.1 - 0.015 15.1 3.8 0.019 14.8 3.2 1.6 1 1 0 1 1 1 0 Trefoil (P-type) domain RhoGAP PF00620.27 KIK49133.1 - 4.2e-46 156.5 0.0 9.1e-46 155.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KIK49133.1 - 1.8e-14 53.8 1.7 1.5e-13 50.8 0.0 2.8 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain TipAS PF07739.13 KIK49133.1 - 0.021 15.3 1.2 5.1 7.7 1.3 2.5 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Baculo_PEP_C PF04513.12 KIK49133.1 - 0.022 14.8 1.1 8.1 6.5 0.0 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SGT1 PF07093.11 KIK49133.1 - 0.06 11.8 2.1 0.099 11.1 2.1 1.3 1 0 0 1 1 1 0 SGT1 protein DUF2347 PF09804.9 KIK49133.1 - 0.087 12.4 0.5 0.16 11.5 0.5 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Leu_zip PF15294.6 KIK49133.1 - 0.088 12.3 7.7 1.9 7.9 6.6 2.2 2 0 0 2 2 2 0 Leucine zipper HemX PF04375.14 KIK49133.1 - 0.22 10.8 4.8 3.8 6.7 2.6 2.3 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Exonuc_VII_L PF02601.15 KIK49133.1 - 0.38 10.3 4.4 0.33 10.5 3.0 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit SlyX PF04102.12 KIK49133.1 - 0.49 11.1 3.1 1.8 9.3 2.0 2.4 2 0 0 2 2 2 0 SlyX Mod_r PF07200.13 KIK49133.1 - 0.85 9.7 11.3 1.5 8.9 6.1 2.8 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.11 KIK49133.1 - 0.93 8.3 9.1 1.6 7.6 6.4 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein TMPIT PF07851.13 KIK49133.1 - 1.1 8.4 3.7 2.7 7.2 3.7 1.5 2 0 0 2 2 2 0 TMPIT-like protein Fib_alpha PF08702.10 KIK49133.1 - 2.7 8.2 8.8 0.83 9.8 5.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family F-box-like PF12937.7 KIK49139.1 - 2.9e-08 33.5 3.0 3.2e-08 33.3 0.1 2.6 3 0 0 3 3 3 1 F-box-like CENP-T_C PF15511.6 KIK49140.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIK49140.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIK49140.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIK49140.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK49140.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIK49140.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 KIK49141.1 - 4.5e-23 82.1 1.4 5.2e-23 81.8 1.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 KIK49141.1 - 6.3e-05 23.6 2.7 7.2e-05 23.4 2.7 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Asp PF00026.23 KIK49143.1 - 4.4e-70 236.6 0.7 5.6e-70 236.3 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK49143.1 - 3.5e-13 50.2 0.6 2.2e-06 28.0 0.0 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Methyltransf_16 PF10294.9 KIK49144.1 - 7.7e-12 45.3 0.0 3.7e-11 43.0 0.0 1.9 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KIK49144.1 - 0.095 12.5 0.0 0.2 11.5 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain AvrM_N PF18247.1 KIK49146.1 - 0.077 12.9 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain F-box-like PF12937.7 KIK49150.1 - 0.013 15.3 0.1 0.035 14.0 0.1 1.7 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 KIK49151.1 - 4.2e-05 23.4 0.0 0.00013 21.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like SF3b1 PF08920.10 KIK49152.1 - 1.5e-22 80.3 0.4 1.5e-22 80.3 0.4 2.3 2 0 0 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 KIK49152.1 - 1.9e-09 37.8 9.8 0.012 16.0 0.1 7.6 4 2 3 8 8 7 2 HEAT repeats HEAT_EZ PF13513.6 KIK49152.1 - 3.4e-09 37.0 5.1 0.013 16.0 0.0 7.4 8 1 1 9 9 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KIK49152.1 - 2.9e-07 31.0 1.7 0.59 10.8 0.0 5.4 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KIK49152.1 - 1.9e-06 27.6 13.8 0.17 12.2 0.1 9.4 12 0 0 12 12 10 1 HEAT repeat Adaptin_N PF01602.20 KIK49152.1 - 4.7e-05 22.2 1.1 0.038 12.6 0.0 3.3 3 0 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.12 KIK49152.1 - 7.6e-05 22.5 0.8 1.8 8.2 0.0 4.8 4 1 1 5 5 5 2 NUC173 domain UME PF08064.13 KIK49152.1 - 0.0002 21.2 1.7 0.87 9.5 0.0 5.6 6 2 1 7 7 7 1 UME (NUC010) domain Cnd1 PF12717.7 KIK49152.1 - 0.00058 19.9 10.7 0.83 9.7 0.0 6.4 8 0 0 8 8 8 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KIK49152.1 - 0.0015 18.2 1.9 1.6 8.2 0.0 3.7 3 1 0 4 4 4 2 CLASP N terminal DUF3110 PF11360.8 KIK49152.1 - 0.016 15.4 0.1 0.057 13.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) Dopey_N PF04118.14 KIK49152.1 - 0.018 14.2 1.6 0.6 9.2 0.0 3.4 4 0 0 4 4 4 0 Dopey, N-terminal DRIM PF07539.12 KIK49152.1 - 0.21 9.8 0.5 4.3 5.5 0.2 3.0 3 1 1 4 4 4 0 Down-regulated in metastasis ACC_central PF08326.12 KIK49153.1 - 4e-247 822.1 0.0 1.9e-246 819.9 0.0 1.8 2 0 0 2 2 2 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KIK49153.1 - 1e-172 575.3 0.0 1.3e-172 574.9 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KIK49153.1 - 1e-50 172.2 0.2 2.5e-50 170.9 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KIK49153.1 - 1.6e-28 99.5 0.1 3.9e-28 98.2 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KIK49153.1 - 3.6e-21 75.3 0.0 6.3e-20 71.3 0.0 3.0 4 0 0 4 4 4 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KIK49153.1 - 2.6e-15 56.0 0.0 5.8e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 KIK49153.1 - 0.00038 20.5 0.0 0.0018 18.3 0.0 2.1 3 0 0 3 3 3 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 KIK49153.1 - 0.033 13.9 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon DUF4999 PF16390.5 KIK49153.1 - 0.036 14.3 0.0 0.096 12.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function Dala_Dala_lig_C PF07478.13 KIK49153.1 - 0.058 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DUF3549 PF12069.8 KIK49153.1 - 0.059 12.4 0.7 0.15 11.1 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) Biotin_lipoyl_2 PF13533.6 KIK49153.1 - 0.089 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like Peptidase_M20 PF01546.28 KIK49154.1 - 1.7e-27 96.5 0.0 2.7e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIK49154.1 - 2.1e-11 43.7 0.0 4.3e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KIK49154.1 - 0.019 14.7 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 DUF4083 PF13314.6 KIK49154.1 - 0.091 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) DUF1659 PF07872.11 KIK49154.1 - 0.15 11.8 0.0 0.64 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1659) Dynein_light PF01221.18 KIK49156.1 - 3.6e-39 133.0 1.0 4.2e-39 132.8 1.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Aconitase_C PF00694.19 KIK49156.1 - 0.079 13.3 0.1 0.13 12.5 0.1 1.4 1 1 0 1 1 1 0 Aconitase C-terminal domain He_PIG PF05345.12 KIK49157.1 - 9.9e-09 35.3 11.3 0.0015 18.7 0.1 5.3 5 0 0 5 5 5 3 Putative Ig domain HEAT_EZ PF13513.6 KIK49158.1 - 4.8e-21 74.9 14.8 2.4e-05 24.7 0.0 9.9 10 0 0 10 10 10 4 HEAT-like repeat HEAT PF02985.22 KIK49158.1 - 2.7e-15 55.1 11.4 0.00031 20.7 0.0 8.8 9 0 0 9 9 7 3 HEAT repeat HEAT_2 PF13646.6 KIK49158.1 - 4e-14 52.8 8.8 0.11 12.9 0.1 7.3 6 2 2 8 8 6 4 HEAT repeats IFRD PF05004.13 KIK49158.1 - 1.3e-09 37.6 0.2 0.00071 18.8 0.0 4.4 3 2 2 5 5 5 3 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 KIK49158.1 - 4.5e-08 33.3 0.0 0.0062 16.6 0.0 3.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 KIK49158.1 - 1.7e-07 31.1 1.8 9.8e-07 28.6 0.3 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 KIK49158.1 - 1.1e-05 26.0 0.0 0.089 13.4 0.0 5.3 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KIK49158.1 - 1.3e-05 24.0 1.6 0.19 10.3 0.0 4.3 3 1 0 4 4 4 2 Adaptin N terminal region MMS19_C PF12460.8 KIK49158.1 - 5.6e-05 22.4 0.0 4.1 6.4 0.0 5.0 5 1 0 5 5 5 2 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 KIK49158.1 - 0.00065 19.6 0.4 31 4.4 0.0 5.6 5 1 1 6 6 6 0 Domain of unknown function (DUF3385) Ipi1_N PF12333.8 KIK49158.1 - 0.0079 16.8 0.0 16 6.1 0.0 4.4 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation XPC-binding PF09280.11 KIK49158.1 - 0.016 14.9 1.4 0.14 11.9 0.2 3.2 3 0 0 3 3 3 0 XPC-binding domain CLASP_N PF12348.8 KIK49158.1 - 0.055 13.0 0.1 6.3 6.3 0.0 4.0 4 2 1 6 6 6 0 CLASP N terminal TIP120 PF08623.10 KIK49158.1 - 0.11 12.3 0.1 3.7 7.3 0.1 3.4 3 1 0 3 3 3 0 TATA-binding protein interacting (TIP20) Kelch_5 PF13854.6 KIK49163.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Kelch motif Glyco_hydro_25 PF01183.20 KIK49164.1 - 6.7e-51 173.0 0.9 7.6e-51 172.8 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 BTB PF00651.31 KIK49165.1 - 1.9e-07 31.3 0.1 1e-06 28.9 0.0 2.2 2 1 0 2 2 2 1 BTB/POZ domain zf-TFIIIC PF12660.7 KIK49166.1 - 1.6e-22 79.4 2.7 4.1e-22 78.0 2.7 1.7 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.7 KIK49166.1 - 8.5e-20 71.4 1.1 8.5e-20 71.4 1.1 2.0 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term UPF0547 PF10571.9 KIK49166.1 - 3.8 7.7 6.2 34 4.6 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DHO_dh PF01180.21 KIK49167.1 - 2.6e-98 328.9 0.0 3.1e-98 328.6 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 KIK49167.1 - 0.01 14.9 0.3 0.085 11.9 1.1 2.1 2 1 0 2 2 2 0 FMN-dependent dehydrogenase Glycos_transf_3 PF00591.21 KIK49168.1 - 2.1e-76 256.9 0.0 2.7e-76 256.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KIK49168.1 - 5.5e-09 35.7 0.1 1.9e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Mito_carr PF00153.27 KIK49172.1 - 1.5e-28 98.5 9.1 5.9e-16 58.2 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2838 PF10998.8 KIK49172.1 - 0.024 14.9 0.1 0.04 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) DHBP_synthase PF00926.19 KIK49173.1 - 2.8e-84 281.5 0.1 3.3e-84 281.2 0.1 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase CbiG_mid PF11761.8 KIK49173.1 - 0.11 12.6 0.0 0.34 11.1 0.0 1.8 1 1 0 1 1 1 0 Cobalamin biosynthesis central region Asp PF00026.23 KIK49174.1 - 9.1e-68 229.0 0.7 1.1e-67 228.7 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK49174.1 - 3.6e-11 43.6 0.4 6.1e-06 26.6 0.1 2.7 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK49174.1 - 0.043 14.5 0.1 0.15 12.7 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease Asp PF00026.23 KIK49175.1 - 3.8e-71 240.1 6.1 4.6e-71 239.8 6.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK49175.1 - 1.4e-09 38.4 2.5 3.3e-07 30.7 2.5 2.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KIK49175.1 - 0.002 17.9 0.0 0.15 11.8 0.0 2.4 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KIK49175.1 - 0.13 12.9 1.2 2.3 8.9 0.0 2.7 3 0 0 3 3 3 0 Aspartyl protease NTP_transferase PF00483.23 KIK49179.1 - 0.13 11.8 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Nucleotidyl transferase LRR_8 PF13855.6 KIK49180.1 - 1.6e-10 40.5 6.7 1.2e-05 25.0 0.2 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KIK49180.1 - 3.4e-09 36.8 8.4 4.4e-06 26.9 2.2 3.2 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KIK49180.1 - 0.077 13.6 9.2 1.8 9.4 0.2 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 KIK49180.1 - 1.9 8.7 4.4 55 4.2 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich repeat Asp PF00026.23 KIK49182.1 - 2.4e-72 244.1 6.5 2.9e-72 243.7 6.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK49182.1 - 1.9e-13 51.0 3.6 1e-07 32.4 0.2 3.1 1 1 2 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK49182.1 - 0.024 15.3 0.4 10 6.9 0.1 3.0 2 1 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.6 KIK49182.1 - 0.14 11.9 0.0 0.45 10.3 0.0 1.8 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Ribosomal_L23 PF00276.20 KIK49183.1 - 4.4e-10 39.8 0.1 1.1e-09 38.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 Metallophos PF00149.28 KIK49184.1 - 4.5e-14 53.4 0.1 1.2e-13 52.1 0.1 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIK49184.1 - 6.4e-05 23.2 0.1 0.0017 18.6 0.0 2.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain AIP3 PF03915.13 KIK49185.1 - 5.9e-149 496.6 2.4 5.9e-149 496.6 2.4 1.7 2 0 0 2 2 2 1 Actin interacting protein 3 HBM PF16591.5 KIK49185.1 - 0.00091 18.7 5.2 0.0054 16.2 2.5 2.6 2 0 0 2 2 2 1 Helical bimodular sensor domain DUF1720 PF08226.11 KIK49185.1 - 0.0077 16.6 0.3 0.035 14.5 0.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1720) APG17 PF04108.12 KIK49185.1 - 0.025 13.7 11.7 1.4 8.0 0.1 3.8 3 1 1 4 4 4 0 Autophagy protein Apg17 Lectin_N PF03954.14 KIK49185.1 - 0.072 12.8 3.2 0.36 10.6 1.4 3.0 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Syntaxin-6_N PF09177.11 KIK49185.1 - 0.087 13.4 11.8 1.7 9.2 0.5 4.3 4 1 0 4 4 3 0 Syntaxin 6, N-terminal OmpH PF03938.14 KIK49185.1 - 0.089 13.1 6.9 1.6 9.1 0.2 3.9 3 1 0 4 4 4 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.12 KIK49185.1 - 0.13 12.7 8.8 0.61 10.6 0.7 4.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein GTP-bdg_M PF16360.5 KIK49185.1 - 0.17 12.5 3.7 6.2 7.5 0.2 3.7 3 0 0 3 3 2 0 GTP-binding GTPase Middle Region Baculo_PEP_C PF04513.12 KIK49185.1 - 0.38 10.8 8.9 6.4 6.8 0.5 4.1 4 2 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin_2 PF14523.6 KIK49185.1 - 0.63 10.4 8.7 3.7 8.0 0.0 4.1 3 1 1 4 4 4 0 Syntaxin-like protein DUF1664 PF07889.12 KIK49185.1 - 1.6 8.8 8.9 2.3 8.3 4.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF5082 PF16888.5 KIK49185.1 - 2.6 8.3 7.1 4.6 7.5 0.5 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) FlgN PF05130.12 KIK49185.1 - 2.6 8.5 5.9 2.4 8.7 0.0 3.5 3 1 1 4 4 4 0 FlgN protein WXG100 PF06013.12 KIK49185.1 - 3.8 7.8 5.1 1e+02 3.2 0.1 3.9 3 1 0 3 3 3 0 Proteins of 100 residues with WXG BAR PF03114.18 KIK49185.1 - 5.5 6.6 6.9 1.2 8.7 2.5 2.2 2 0 0 2 2 2 0 BAR domain Spc7 PF08317.11 KIK49185.1 - 6.1 5.6 10.3 14 4.5 2.5 3.2 2 1 0 3 3 3 0 Spc7 kinetochore protein ABC_membrane PF00664.23 KIK49186.1 - 4.7e-105 351.2 34.5 3.7e-53 181.0 14.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK49186.1 - 3.3e-67 225.2 0.0 3.6e-32 111.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIK49186.1 - 3.6e-14 52.7 1.8 2.9e-05 23.6 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KIK49186.1 - 2.6e-07 29.8 1.7 0.0053 15.6 0.1 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 KIK49186.1 - 1.2e-06 28.2 1.9 0.0024 17.5 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KIK49186.1 - 5.2e-06 26.9 3.5 0.01 16.3 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KIK49186.1 - 5.4e-06 25.8 0.0 0.026 13.8 0.0 2.6 3 0 0 3 3 2 2 Zeta toxin RsgA_GTPase PF03193.16 KIK49186.1 - 1.2e-05 25.3 0.0 0.18 11.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KIK49186.1 - 1.3e-05 25.2 0.0 0.13 12.0 0.0 3.8 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KIK49186.1 - 2.6e-05 24.5 2.2 0.052 13.8 0.1 3.9 3 2 0 3 3 2 1 AAA domain AAA_15 PF13175.6 KIK49186.1 - 3.5e-05 23.7 0.0 0.039 13.7 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KIK49186.1 - 0.00027 21.4 0.2 10 6.5 0.0 4.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 KIK49186.1 - 0.00062 19.0 0.0 0.23 10.6 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit SbcCD_C PF13558.6 KIK49186.1 - 0.0013 18.9 3.0 2.5 8.4 0.3 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KIK49186.1 - 0.0013 18.5 0.6 3 7.5 0.1 3.3 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KIK49186.1 - 0.0022 17.5 0.0 0.54 9.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 KIK49186.1 - 0.0023 18.0 0.0 2 8.4 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KIK49186.1 - 0.0031 17.1 2.4 0.37 10.4 0.1 3.1 4 0 0 4 4 2 1 AAA domain AAA_23 PF13476.6 KIK49186.1 - 0.0068 16.9 0.4 1.6 9.2 0.4 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIK49186.1 - 0.0093 16.1 0.0 7 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KIK49186.1 - 0.0095 15.8 0.1 1.5 8.7 0.1 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_18 PF13238.6 KIK49186.1 - 0.013 16.0 0.0 1.7 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KIK49186.1 - 0.015 15.4 1.1 5.7 7.0 0.3 3.4 4 0 0 4 4 4 0 Helicase HerA, central domain AAA_28 PF13521.6 KIK49186.1 - 0.016 15.4 0.7 2.1 8.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain PRK PF00485.18 KIK49186.1 - 0.017 14.8 0.0 0.77 9.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 KIK49186.1 - 0.022 15.1 0.1 5.2 7.5 0.0 3.5 3 0 0 3 3 3 0 RNA helicase MMR_HSR1 PF01926.23 KIK49186.1 - 0.055 13.6 0.0 7.7 6.6 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Rad17 PF03215.15 KIK49186.1 - 0.066 13.1 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain NB-ARC PF00931.22 KIK49186.1 - 0.15 11.2 0.1 5.3 6.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 KIK49186.1 - 0.19 11.4 0.4 24 4.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain PS_Dcarbxylase PF02666.15 KIK49188.1 - 1.2e-46 158.9 0.0 1.9e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase NopRA1 PF16201.5 KIK49188.1 - 0.035 13.7 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 Usg PF06233.12 KIK49188.1 - 0.19 11.9 0.1 3.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Usg-like family FA_desaturase PF00487.24 KIK49189.1 - 1.6e-16 61.0 20.3 3.1e-16 60.0 20.3 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KIK49189.1 - 1.9e-11 43.9 0.0 4.1e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain adh_short PF00106.25 KIK49190.1 - 4.1e-19 68.8 1.5 4.7e-19 68.6 1.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK49190.1 - 2.4e-12 46.9 0.6 2.9e-12 46.7 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK49190.1 - 2.6e-08 34.0 0.4 3e-08 33.8 0.4 1.0 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIK49190.1 - 0.00028 20.4 0.1 0.00031 20.3 0.1 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIK49190.1 - 0.0025 17.3 0.0 0.0029 17.1 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KIK49190.1 - 0.003 17.8 0.2 0.0039 17.5 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 KIK49190.1 - 0.004 16.8 0.3 0.0052 16.4 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.20 KIK49190.1 - 0.0052 16.8 0.1 0.0062 16.6 0.1 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KIK49190.1 - 0.016 14.6 0.0 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KIK49190.1 - 0.026 14.4 0.2 0.03 14.2 0.2 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain His_biosynth PF00977.21 KIK49190.1 - 0.032 13.7 0.1 0.036 13.5 0.1 1.1 1 0 0 1 1 1 0 Histidine biosynthesis protein Csm1_B PF18211.1 KIK49190.1 - 0.061 13.2 0.2 0.26 11.2 0.0 1.8 1 1 1 2 2 2 0 Csm1 subunit domain B THF_DHG_CYH_C PF02882.19 KIK49190.1 - 0.071 12.4 0.1 0.096 12.0 0.1 1.1 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 KIK49190.1 - 0.085 13.3 0.1 0.097 13.1 0.1 1.2 1 0 0 1 1 1 0 Putative NAD(P)-binding ETF PF01012.21 KIK49191.1 - 6.1e-37 127.3 1.0 1.1e-36 126.4 1.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KIK49191.1 - 2.3e-32 110.9 0.4 5.4e-32 109.7 0.4 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Ribosomal_L24e PF01246.20 KIK49192.1 - 5.4e-33 113.0 6.4 1.1e-32 112.0 6.4 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e Cytochrom_C550 PF14495.6 KIK49192.1 - 0.048 13.4 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c-550 domain zf-FCS PF06467.14 KIK49192.1 - 0.074 13.0 5.3 0.13 12.2 5.3 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif ATG_C PF09333.11 KIK49193.1 - 6.2e-38 129.0 0.4 1.4e-37 127.9 0.4 1.7 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain ATG2_CAD PF13329.6 KIK49193.1 - 8.5e-11 41.8 0.0 2.3e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif Chorein_N PF12624.7 KIK49193.1 - 1.6e-05 25.0 0.0 0.0045 17.1 0.0 2.8 1 1 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 KIK49193.1 - 0.0014 18.5 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal RPA_C PF08784.11 KIK49195.1 - 9e-14 52.0 0.0 2e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KIK49195.1 - 1.8e-07 31.1 0.1 4e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 KIK49195.1 - 0.0026 17.6 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 MarR_2 PF12802.7 KIK49195.1 - 0.026 14.4 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_6 PF01418.17 KIK49195.1 - 0.041 13.9 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family MarR PF01047.22 KIK49195.1 - 0.17 11.9 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 MarR family GntR PF00392.21 KIK49195.1 - 0.18 11.5 0.0 0.38 10.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_5 PF01022.20 KIK49195.1 - 0.19 11.7 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family NatB_MDM20 PF09797.9 KIK49196.1 - 3.7e-80 269.7 1.2 8.1e-80 268.6 1.2 1.6 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 KIK49196.1 - 2.8e-05 24.5 0.1 0.086 13.4 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat NCE101 PF11654.8 KIK49197.1 - 2.2e-19 68.9 0.1 6.3e-19 67.4 0.0 1.6 2 0 0 2 2 2 1 Non-classical export protein 1 Ribonucleas_3_3 PF14622.6 KIK49198.1 - 1.5e-15 57.5 0.1 7.2e-13 48.8 0.1 2.1 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KIK49198.1 - 0.0041 17.7 0.0 0.0065 17.1 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease III domain PAC3 PF10178.9 KIK49199.1 - 2.9e-05 24.1 0.1 0.0001 22.4 0.1 1.8 1 1 0 1 1 1 1 Proteasome assembly chaperone 3 Med16 PF11635.8 KIK49200.1 - 2.5e-06 25.8 0.0 3.7e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 16 TruB_N PF01509.18 KIK49201.1 - 7.2e-44 149.8 0.0 2.1e-43 148.3 0.0 1.7 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KIK49201.1 - 2.6e-05 24.3 0.0 7e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain DHDPS PF00701.22 KIK49202.1 - 5.4e-28 97.5 0.0 2.2e-27 95.5 0.0 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family PNTB PF02233.16 KIK49203.1 - 1.6e-174 581.2 22.9 1.6e-174 581.2 22.9 2.2 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KIK49203.1 - 1.2e-73 247.0 1.1 4e-73 245.3 1.1 2.0 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KIK49203.1 - 1.9e-43 148.0 0.4 5.2e-43 146.6 0.1 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KIK49203.1 - 6.7e-32 109.8 3.2 6.7e-32 109.8 3.2 4.6 2 1 1 3 3 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch Pyr_redox_2 PF07992.14 KIK49203.1 - 0.011 15.0 0.2 0.021 14.1 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KIK49203.1 - 0.016 14.6 1.2 2.1 7.7 0.1 3.6 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KIK49203.1 - 0.064 13.2 0.3 0.45 10.5 0.3 2.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAS PF03059.16 KIK49203.1 - 0.12 11.6 0.0 0.32 10.3 0.0 1.6 1 1 0 1 1 1 0 Nicotianamine synthase protein PRIMA1 PF16101.5 KIK49203.1 - 0.2 11.7 1.6 0.48 10.5 1.6 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 NAD_binding_8 PF13450.6 KIK49203.1 - 0.45 10.8 7.8 0.26 11.5 0.7 3.8 4 0 0 4 4 4 0 NAD(P)-binding Rossmann-like domain Nuc_sug_transp PF04142.15 KIK49204.1 - 5.8e-95 318.1 15.8 7.8e-83 278.2 14.2 2.0 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 KIK49204.1 - 0.00048 20.3 1.6 0.00048 20.3 1.6 2.8 3 0 0 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 KIK49204.1 - 0.0023 16.9 1.9 0.0023 16.9 1.9 2.0 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 KIK49204.1 - 0.049 12.8 16.9 0.21 10.7 16.9 2.0 1 1 0 1 1 1 0 UAA transporter family Tudor_3 PF18115.1 KIK49206.1 - 4.7e-15 55.2 0.9 2.3e-13 49.8 0.1 2.5 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KIK49206.1 - 6.2e-08 32.7 0.1 2e-07 31.1 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4537) DUF1325 PF07039.11 KIK49206.1 - 1.6e-05 25.0 0.1 0.00029 20.9 0.0 2.6 2 0 0 2 2 2 1 SGF29 tudor-like domain BRCT PF00533.26 KIK49206.1 - 1.8e-05 25.0 0.1 0.15 12.5 0.0 3.5 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain Tudor_2 PF18104.1 KIK49206.1 - 7.7e-05 22.3 2.3 0.0022 17.6 0.1 2.4 2 0 0 2 2 2 1 Jumonji domain-containing protein 2A Tudor domain Rad9_Rad53_bind PF08605.10 KIK49206.1 - 0.00087 19.5 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT_2 PF16589.5 KIK49206.1 - 0.0029 18.0 0.0 1.9 8.9 0.0 2.7 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain TUDOR_5 PF18359.1 KIK49206.1 - 0.0076 15.9 0.1 0.084 12.6 0.0 2.2 2 0 0 2 2 2 1 Histone methyltransferase Tudor domain 1 Agenet PF05641.12 KIK49206.1 - 0.014 15.9 0.0 1.9 9.0 0.0 2.7 2 0 0 2 2 2 0 Agenet domain BRCT_3 PF18428.1 KIK49206.1 - 0.036 14.1 0.0 7.8 6.6 0.0 2.7 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain 53-BP1_Tudor PF09038.10 KIK49206.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor Chromo PF00385.24 KIK49207.1 - 2.3e-09 37.0 3.6 4.2e-09 36.2 3.6 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain GYF PF02213.16 KIK49208.1 - 7e-07 28.8 2.1 1.8e-06 27.5 2.1 1.7 1 0 0 1 1 1 1 GYF domain SNF2_N PF00176.23 KIK49209.1 - 1.8e-55 188.1 0.0 2.9e-55 187.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 KIK49209.1 - 5.3e-44 150.5 11.6 9.3e-44 149.7 11.6 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 KIK49209.1 - 2.1e-16 60.2 0.0 4.4e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK49209.1 - 4.2e-06 26.9 0.0 1.3e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KIK49209.1 - 0.0014 17.8 0.0 0.0014 17.8 0.0 2.6 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 U1snRNP70_N PF12220.8 KIK49209.1 - 1.3 9.7 11.5 0.048 14.3 4.0 2.4 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal SET PF00856.28 KIK49210.1 - 1.4e-15 58.1 1.6 1e-14 55.3 0.3 2.8 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 KIK49210.1 - 1.8e-10 41.4 8.9 4.6e-10 40.1 6.2 2.3 2 0 0 2 2 2 1 Pre-SET motif Chromo PF00385.24 KIK49210.1 - 1.1 9.2 5.6 0.76 9.7 0.4 2.4 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain PQ-loop PF04193.14 KIK49212.1 - 1e-39 134.1 6.0 5.1e-20 71.0 0.1 2.4 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 KIK49212.1 - 0.018 15.1 0.7 0.041 13.9 0.1 1.8 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange CLTH PF10607.9 KIK49213.1 - 1.2e-17 64.2 0.0 1.8e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KIK49213.1 - 0.035 14.1 0.1 0.082 12.9 0.0 1.7 2 0 0 2 2 2 0 LisH Coagulin PF02035.15 KIK49214.1 - 0.033 14.1 0.0 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 Coagulin Ribosomal_L30_N PF08079.12 KIK49215.1 - 5.5e-29 100.2 14.8 1e-28 99.4 14.8 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KIK49215.1 - 1.7e-18 66.2 1.2 3.9e-18 65.1 1.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Tipalpha PF16753.5 KIK49215.1 - 0.092 12.6 0.6 3.1 7.6 0.0 2.4 1 1 1 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter MCPVI PF02993.14 KIK49216.1 - 0.03 14.1 0.1 0.036 13.9 0.1 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Ad_Cy_reg PF16701.5 KIK49216.1 - 0.12 12.1 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase regulatory domain DUF5305 PF17231.2 KIK49217.1 - 0.092 12.1 1.6 0.13 11.7 1.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF456 PF04306.13 KIK49217.1 - 0.098 12.9 3.2 0.24 11.7 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_Omp PF13488.6 KIK49219.1 - 0.026 14.5 7.8 0.058 13.4 7.8 1.5 1 0 0 1 1 1 0 Glycine zipper SKG6 PF08693.10 KIK49219.1 - 0.041 13.3 1.8 0.087 12.3 1.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Yip1 PF04893.17 KIK49219.1 - 0.98 9.1 7.4 1.1 8.9 0.6 2.3 2 0 0 2 2 2 0 Yip1 domain WD40 PF00400.32 KIK49220.1 - 6.4e-38 128.1 13.8 7.4e-06 26.6 0.0 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK49220.1 - 1.2e-12 47.9 0.8 0.11 12.8 0.0 6.5 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 KIK49220.1 - 5.3e-08 33.3 0.2 5.3e-08 33.3 0.2 3.0 2 1 1 3 3 3 1 Heterokaryon incompatibility protein (HET) TPR_2 PF07719.17 KIK49220.1 - 5.5e-08 32.3 10.5 0.23 11.6 0.1 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat eIF2A PF08662.11 KIK49220.1 - 8.1e-07 29.1 0.0 0.00069 19.6 0.0 3.3 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A TPR_1 PF00515.28 KIK49220.1 - 6.3e-05 22.6 7.7 0.25 11.2 0.1 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat DUF1513 PF07433.11 KIK49220.1 - 0.0017 17.5 0.4 0.77 8.8 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1513) TPR_11 PF13414.6 KIK49220.1 - 0.0018 18.0 3.5 0.072 12.8 0.3 3.7 3 0 0 3 3 3 1 TPR repeat DUF3856 PF12968.7 KIK49220.1 - 0.033 14.3 2.3 22 5.1 0.0 4.0 3 1 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_14 PF13428.6 KIK49220.1 - 0.079 13.8 6.0 21 6.3 0.2 5.6 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIK49220.1 - 0.11 12.5 0.1 29 5.0 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Phage_lysozyme PF00959.19 KIK49220.1 - 0.14 12.7 0.2 17 5.9 0.1 3.4 4 0 0 4 4 4 0 Phage lysozyme MIT PF04212.18 KIK49220.1 - 0.43 10.7 3.0 1.3 9.2 0.2 3.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 KIK49220.1 - 1.8 8.1 4.3 15 5.1 0.2 3.2 3 0 0 3 3 3 0 SHNi-TPR BTAD PF03704.17 KIK49220.1 - 6.2 7.3 7.8 75 3.7 0.1 4.1 4 1 1 5 5 5 0 Bacterial transcriptional activator domain Aldo_ket_red PF00248.21 KIK49221.1 - 1.3e-31 109.9 0.0 2.2e-30 105.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Cytidylate_kin2 PF13189.6 KIK49221.1 - 0.085 13.0 0.0 6.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase-like family HyaE PF07449.11 KIK49221.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Snf7 PF03357.21 KIK49222.1 - 2.2e-20 73.0 5.6 3.1e-20 72.5 5.6 1.2 1 0 0 1 1 1 1 Snf7 SNARE PF05739.19 KIK49222.1 - 0.004 17.1 0.4 1.3 9.0 0.2 2.6 2 0 0 2 2 2 2 SNARE domain Bul1_C PF04426.12 KIK49222.1 - 0.017 14.5 0.4 0.031 13.7 0.4 1.4 1 0 0 1 1 1 0 Bul1 C terminus AKNA PF12443.8 KIK49222.1 - 0.038 14.6 0.1 0.12 13.1 0.1 1.8 1 0 0 1 1 1 0 AT-hook-containing transcription factor TolA_bind_tri PF16331.5 KIK49222.1 - 0.045 13.8 2.0 0.067 13.3 0.6 2.0 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF4795 PF16043.5 KIK49222.1 - 0.8 9.3 8.9 2.1 7.9 2.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Laminin_II PF06009.12 KIK49222.1 - 1.1 9.3 7.0 0.23 11.4 1.9 2.1 1 1 1 2 2 2 0 Laminin Domain II Baculo_PEP_C PF04513.12 KIK49222.1 - 1.3 9.1 6.1 2.3 8.2 4.8 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.11 KIK49222.1 - 4.7 7.3 5.5 1.2 9.2 0.4 2.4 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 OTU PF02338.19 KIK49223.1 - 3.4e-05 24.3 0.0 5.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease PNP_UDP_1 PF01048.20 KIK49223.1 - 0.0066 15.7 0.0 0.02 14.1 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily Exo_endo_phos PF03372.23 KIK49224.1 - 1.2e-13 51.2 0.0 1.6e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KIK49224.1 - 0.042 13.7 0.0 4.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase RLL PF10036.9 KIK49224.1 - 0.57 10.0 2.2 0.7 9.7 0.0 1.9 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein Tom37 PF10568.9 KIK49226.1 - 1.9e-34 118.7 0.2 1.9e-32 112.2 0.0 2.3 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KIK49226.1 - 5.8e-11 43.0 0.0 1.6e-10 41.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KIK49226.1 - 9.8e-10 38.1 0.1 1.8e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIK49226.1 - 9.9e-06 25.5 0.1 1.9e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIK49226.1 - 0.025 14.8 0.0 0.075 13.2 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIK49226.1 - 0.069 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TAFII55_N PF04658.13 KIK49227.1 - 1.5e-51 174.3 1.8 6.3e-51 172.3 0.1 2.6 2 1 0 2 2 2 1 TAFII55 protein conserved region DUF2968 PF11180.8 KIK49227.1 - 0.11 12.1 2.8 0.25 11.0 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) BUD22 PF09073.10 KIK49227.1 - 0.19 11.0 24.5 0.1 11.9 20.7 2.2 1 1 1 2 2 2 0 BUD22 SIR4_SID PF16991.5 KIK49227.1 - 0.52 10.3 8.9 27 4.8 0.0 2.4 2 0 0 2 2 2 0 Sir4 SID domain FlxA PF14282.6 KIK49227.1 - 1.4 9.0 6.1 0.67 10.0 3.1 1.9 1 1 0 2 2 2 0 FlxA-like protein NOA36 PF06524.12 KIK49227.1 - 4.4 6.5 24.4 9.8 5.4 24.4 1.5 1 0 0 1 1 1 0 NOA36 protein Gaa1 PF04114.14 KIK49228.1 - 4.2e-113 379.0 8.0 5.8e-112 375.3 8.0 2.0 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component UCH PF00443.29 KIK49229.1 - 3.6e-34 118.4 0.7 8e-34 117.3 0.7 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIK49229.1 - 4.7e-16 59.3 2.7 4.7e-16 59.3 2.7 3.7 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KIK49229.1 - 4.2e-05 23.2 0.2 0.0001 22.0 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin family zf-RanBP PF00641.18 KIK49229.1 - 0.0071 15.6 1.3 0.0071 15.6 1.3 2.7 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others Rad60-SLD PF11976.8 KIK49229.1 - 0.014 15.2 0.9 0.068 13.0 0.1 2.5 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like DUSP PF06337.12 KIK49229.1 - 0.022 15.4 0.0 12 6.6 0.0 2.7 2 0 0 2 2 2 0 DUSP domain LUC7 PF03194.15 KIK49231.1 - 8.8e-70 235.2 1.7 1.2e-69 234.8 1.7 1.1 1 0 0 1 1 1 1 LUC7 N_terminus DnaJ PF00226.31 KIK49232.1 - 1e-16 60.8 0.0 2.8e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain Ank_2 PF12796.7 KIK49232.1 - 5.2e-11 43.0 0.0 4.7e-06 27.1 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIK49232.1 - 1e-07 32.3 0.0 2.1e-05 25.0 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIK49232.1 - 0.00016 21.9 0.0 3.5 8.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KIK49232.1 - 0.022 15.1 0.0 0.12 12.7 0.0 2.2 1 1 1 2 2 2 0 Ankyrin repeats (many copies) VIT1 PF01988.19 KIK49232.1 - 1.9 8.3 8.2 4.4 7.1 8.2 1.7 1 1 0 1 1 1 0 VIT family BCS1_N PF08740.11 KIK49234.1 - 6.5e-49 166.5 2.6 9e-49 166.0 2.6 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KIK49234.1 - 9.1e-19 68.2 0.0 1.6e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KIK49234.1 - 0.00042 19.9 0.0 0.014 14.9 0.0 2.7 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KIK49234.1 - 0.0005 20.5 0.0 0.0023 18.3 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KIK49234.1 - 0.0086 15.6 0.0 0.028 13.9 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 KIK49234.1 - 0.013 15.7 0.0 0.032 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KIK49234.1 - 0.016 14.9 0.0 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 KIK49234.1 - 0.025 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIK49234.1 - 0.029 14.7 0.3 0.2 11.9 0.1 2.7 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 KIK49234.1 - 0.047 13.6 0.0 1.3 8.9 0.0 2.2 1 1 0 2 2 2 0 Rad17 P-loop domain AAA_18 PF13238.6 KIK49234.1 - 0.057 14.0 0.0 0.19 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KIK49234.1 - 0.096 11.8 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KIK49234.1 - 0.097 13.1 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 KIK49234.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KIK49234.1 - 0.19 12.2 0.0 0.3 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain WBS_methylT PF12589.8 KIK49235.1 - 2.3e-21 76.3 10.2 2.3e-21 76.3 10.2 1.5 2 0 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KIK49235.1 - 5.2e-09 36.6 0.0 1e-08 35.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK49235.1 - 8.5e-08 32.8 0.0 1.8e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK49235.1 - 2.9e-05 24.7 0.0 7.8e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK49235.1 - 5.3e-05 23.1 0.0 8.7e-05 22.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK49235.1 - 0.0014 18.4 0.0 0.0033 17.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 KIK49235.1 - 0.0089 16.4 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase TRAPP PF04051.16 KIK49236.1 - 1.1e-35 122.6 0.0 1.5e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ribosomal_S13 PF00416.22 KIK49237.1 - 6.4e-22 78.3 0.0 4.1e-11 43.4 0.3 2.0 2 0 0 2 2 2 2 Ribosomal protein S13/S18 FbpA PF05833.11 KIK49237.1 - 0.0018 17.1 0.0 0.0056 15.5 0.0 1.7 1 1 1 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) IMS_HHH PF11798.8 KIK49237.1 - 0.048 14.0 0.0 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 IMS family HHH motif XAP5 PF04921.14 KIK49238.1 - 8.6e-87 291.1 6.6 8.6e-87 291.1 6.6 2.0 1 1 1 2 2 2 1 XAP5, circadian clock regulator RuBisCO_small PF00101.20 KIK49238.1 - 0.071 13.1 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain Mito_carr PF00153.27 KIK49239.1 - 5.7e-36 122.3 0.8 5.7e-16 58.2 0.1 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein Rrn6 PF10214.9 KIK49240.1 - 7.5e-14 51.2 0.4 0.00018 20.2 0.4 3.3 3 1 0 3 3 3 3 RNA polymerase I-specific transcription-initiation factor Ribosomal_L3 PF00297.22 KIK49241.1 - 3.5e-20 72.3 1.6 1.3e-18 67.1 0.6 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 Cofilin_ADF PF00241.20 KIK49242.1 - 6.8e-22 77.5 0.1 7.6e-22 77.4 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MFS_1 PF07690.16 KIK49243.1 - 2.7e-31 108.8 32.0 1.6e-24 86.5 18.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KIK49243.1 - 3.2 5.9 14.2 0.33 9.2 5.7 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Exo_endo_phos PF03372.23 KIK49244.1 - 4.2e-07 29.7 0.0 1.4e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PBP_N PF17093.5 KIK49244.1 - 0.051 13.8 0.3 0.14 12.4 0.3 1.8 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus OPT PF03169.15 KIK49245.1 - 1e-155 519.9 41.5 1.2e-155 519.7 41.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein EIAV_Rev PF11129.8 KIK49246.1 - 0.047 13.9 0.5 0.079 13.2 0.5 1.3 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus OPT PF03169.15 KIK49247.1 - 1.3e-157 526.1 41.1 1.5e-157 525.9 41.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2207 PF09972.9 KIK49247.1 - 2.5 6.8 4.8 3.6 6.2 0.2 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Mannosyl_trans PF05007.13 KIK49248.1 - 1e-74 251.7 13.5 1.4e-74 251.2 13.5 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KIK49248.1 - 2.4e-13 49.9 7.4 4.4e-13 49.0 7.4 1.4 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 KIK49248.1 - 0.00015 21.6 9.9 0.00015 21.6 9.9 2.2 1 1 0 2 2 2 1 Glycosyltransferase family 87 Arf PF00025.21 KIK49249.1 - 5.5e-68 227.8 0.0 6.2e-68 227.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KIK49249.1 - 5.8e-12 45.4 0.0 1.6e-08 34.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KIK49249.1 - 5.3e-11 42.3 0.0 6.8e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KIK49249.1 - 6.2e-08 32.9 0.0 1.5e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KIK49249.1 - 9.1e-08 32.2 0.0 1.7e-07 31.3 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 KIK49249.1 - 1.9e-06 27.5 0.0 2.2e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KIK49249.1 - 3.1e-05 23.4 0.0 3.5e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KIK49249.1 - 0.048 13.4 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KIK49249.1 - 0.16 11.6 0.0 6.6 6.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NMT_C PF02799.15 KIK49250.1 - 1.1e-81 273.4 0.0 2.2e-81 272.4 0.0 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KIK49250.1 - 8.5e-78 259.7 0.0 1.3e-77 259.1 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 KIK49250.1 - 0.00011 22.3 0.0 0.00062 19.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIK49250.1 - 0.024 14.8 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Cas_Csd1 PF09709.10 KIK49250.1 - 0.14 10.8 0.1 0.28 9.8 0.1 1.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csd1) VCX_VCY PF15231.6 KIK49250.1 - 5.4 7.7 9.9 1.2 9.8 3.2 2.2 1 1 1 2 2 2 0 Variable charge X/Y family UFD1 PF03152.14 KIK49251.1 - 1.4e-68 229.7 0.0 1.9e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Cpn60_TCP1 PF00118.24 KIK49252.1 - 2.2e-147 491.7 13.1 2.5e-147 491.5 13.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSL_N PF06350.12 KIK49252.1 - 0.051 12.5 0.0 0.099 11.6 0.0 1.4 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus ATP-synt_D PF01813.17 KIK49253.1 - 2e-70 236.7 1.4 2.6e-70 236.2 1.4 1.2 1 0 0 1 1 1 1 ATP synthase subunit D HtrL_YibB PF09612.10 KIK49253.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) FRG1 PF06229.12 KIK49254.1 - 8.2e-26 90.9 0.0 8.2e-26 90.9 0.0 1.5 2 0 0 2 2 2 1 FRG1-like domain DUF1754 PF08555.10 KIK49254.1 - 2.3e-05 25.1 10.0 0.017 15.9 1.3 2.2 2 0 0 2 2 2 2 Eukaryotic family of unknown function (DUF1754) Fascin PF06268.13 KIK49254.1 - 0.081 13.2 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Fascin domain BRF1 PF07741.13 KIK49254.1 - 0.11 12.8 7.7 0.22 11.9 3.5 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain HEPN_RiboL-PSP PF18735.1 KIK49255.1 - 0.23 11.4 0.0 0.36 10.7 0.0 1.2 1 0 0 1 1 1 0 RiboL-PSP-HEPN SRPRB PF09439.10 KIK49256.1 - 3e-18 65.9 0.0 4.3e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KIK49256.1 - 4.3e-11 42.6 0.0 6.7e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIK49256.1 - 3.2e-05 24.0 0.0 5.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KIK49256.1 - 0.00011 21.6 0.0 0.00015 21.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.19 KIK49256.1 - 0.006 16.2 0.2 0.49 10.0 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KIK49256.1 - 0.0083 16.3 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KIK49256.1 - 0.0097 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIK49256.1 - 0.028 14.8 0.1 0.049 14.0 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 KIK49256.1 - 0.035 13.6 0.1 4.8 6.7 0.0 2.2 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 KIK49256.1 - 0.11 12.3 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KIK49256.1 - 0.15 11.5 0.1 0.84 9.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 KIK49256.1 - 0.23 11.8 0.6 2 8.7 0.0 2.5 2 1 1 3 3 3 0 AAA domain G-alpha PF00503.20 KIK49256.1 - 0.28 10.3 0.0 9.6 5.3 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit OGG_N PF07934.12 KIK49257.1 - 7.9e-33 113.1 0.1 1.8e-32 111.9 0.1 1.6 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KIK49257.1 - 1.4e-13 51.2 0.0 2.8e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KIK49257.1 - 0.072 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF2749 PF10907.8 KIK49257.1 - 2.5 8.3 6.0 0.52 10.5 0.7 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) PHC2_SAM_assoc PF16616.5 KIK49257.1 - 6.2 7.7 9.3 2.5 8.9 5.1 2.2 2 1 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 NPR2 PF06218.11 KIK49258.1 - 1.2e-97 327.4 6.4 3.6e-81 273.2 6.3 3.6 2 1 1 3 3 3 2 Nitrogen permease regulator 2 RTC PF01137.21 KIK49259.1 - 1.7e-58 197.5 0.0 1.9e-58 197.3 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KIK49259.1 - 5.1e-36 123.3 0.0 8.5e-36 122.6 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain ThiF PF00899.21 KIK49260.1 - 3.5e-59 200.1 0.0 4.9e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KIK49260.1 - 4.2e-27 94.1 0.1 6.4e-27 93.5 0.1 1.3 1 0 0 1 1 1 1 E2 binding domain UDPG_MGDP_dh_N PF03721.14 KIK49260.1 - 0.039 13.5 0.1 0.13 11.8 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 KIK49260.1 - 0.048 13.7 0.1 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KIK49260.1 - 0.065 13.8 0.2 0.19 12.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KIK49260.1 - 0.088 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ecm33 PF12454.8 KIK49260.1 - 0.47 10.7 2.6 0.95 9.7 2.6 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein zf_CCCH_4 PF18345.1 KIK49261.1 - 1e-06 28.6 2.0 3.6e-06 26.8 2.0 2.1 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KIK49261.1 - 2.3e-06 28.3 0.3 4.4e-06 27.3 0.3 1.4 1 0 0 1 1 1 1 Torus domain zf-CCCH_3 PF15663.5 KIK49261.1 - 0.00016 21.9 0.3 0.00043 20.5 0.1 1.8 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH PF00642.24 KIK49261.1 - 0.0003 20.6 2.7 0.00086 19.2 2.7 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KIK49261.1 - 0.00096 18.9 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_2 PF14608.6 KIK49261.1 - 0.0027 18.1 2.5 0.0027 18.1 2.5 1.9 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 KIK49261.1 - 0.005 16.6 3.2 0.014 15.2 3.2 1.8 1 0 0 1 1 1 1 CCCH-type zinc finger Sulf_transp PF04143.14 KIK49262.1 - 4.9e-14 52.6 22.7 7.3e-12 45.5 7.7 2.7 2 1 0 2 2 2 2 Sulphur transport tRNA_int_endo PF01974.17 KIK49263.1 - 7.6e-19 67.6 0.4 6.3e-18 64.6 0.4 2.2 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KIK49263.1 - 0.00027 20.5 0.0 0.0049 16.5 0.0 2.3 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain DUF1708 PF08101.11 KIK49263.1 - 0.0079 15.4 0.2 0.064 12.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1708) LEA_2 PF03168.13 KIK49264.1 - 4.3e-05 24.0 0.1 7.2e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF1356 PF07092.12 KIK49264.1 - 0.0012 18.2 2.1 0.0016 17.7 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) zf-RING_5 PF14634.6 KIK49265.1 - 1.2e-08 34.8 2.8 1.2e-08 34.8 2.8 1.7 2 0 0 2 2 2 1 zinc-RING finger domain bZIP_1 PF00170.21 KIK49265.1 - 0.022 14.8 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 bZIP transcription factor zf-C3HC4 PF00097.25 KIK49265.1 - 0.035 14.0 4.2 0.068 13.1 4.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK49265.1 - 0.074 13.1 6.6 0.16 12.0 6.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger HALZ PF02183.18 KIK49265.1 - 0.17 12.2 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper zf-C3HC4_3 PF13920.6 KIK49265.1 - 0.54 10.2 3.5 1.5 8.7 3.5 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK49265.1 - 3.6 8.0 9.6 0.5 10.8 5.5 1.7 2 0 0 2 2 2 0 Ring finger domain JmjC PF02373.22 KIK49266.1 - 5.1e-12 46.2 0.0 1.3e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase HAP1_N PF04849.13 KIK49266.1 - 0.42 9.8 2.9 0.17 11.1 0.4 1.5 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Pkinase PF00069.25 KIK49267.1 - 3.6e-26 92.1 0.0 4.6e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK49267.1 - 2e-12 47.0 0.0 2.9e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK49267.1 - 7.2e-07 28.3 0.0 9.3e-07 27.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK49267.1 - 0.032 14.2 0.3 14 5.5 0.0 2.9 2 1 0 3 3 3 0 Phosphotransferase enzyme family Pyr_redox_3 PF13738.6 KIK49268.1 - 1.1e-11 44.5 0.2 2.3e-10 40.2 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KIK49268.1 - 4.4e-11 41.9 0.1 2.9e-10 39.2 0.1 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KIK49268.1 - 1.8e-10 40.9 0.0 3.9e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIK49268.1 - 3.2e-08 33.1 0.0 2.4e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIK49268.1 - 4.6e-07 29.3 0.0 4.4e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KIK49268.1 - 0.00021 21.0 0.0 0.00032 20.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIK49268.1 - 0.0023 17.9 0.0 0.027 14.4 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KIK49268.1 - 0.023 13.8 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KIK49268.1 - 0.13 11.5 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KIK49268.1 - 0.18 10.8 0.1 0.3 10.1 0.1 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein Vac_ImportDeg PF09783.9 KIK49269.1 - 3.9e-54 182.8 0.0 1.6e-53 180.8 0.0 1.8 1 1 0 1 1 1 1 Vacuolar import and degradation protein DZR PF12773.7 KIK49269.1 - 0.15 12.1 1.3 0.38 10.8 1.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon Ras PF00071.22 KIK49272.1 - 1.4e-49 167.8 0.0 1.7e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK49272.1 - 5.5e-30 104.1 0.0 7.8e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK49272.1 - 1.2e-09 37.9 0.0 1.6e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIK49272.1 - 0.00063 19.2 0.0 0.00079 18.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIK49272.1 - 0.0023 18.0 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KIK49272.1 - 0.0081 15.4 1.9 1.1 8.3 0.2 2.5 2 1 0 2 2 2 2 G-protein alpha subunit RNA_helicase PF00910.22 KIK49272.1 - 0.018 15.4 0.1 0.14 12.5 0.1 2.1 1 1 0 1 1 1 0 RNA helicase Pox_A32 PF04665.12 KIK49272.1 - 0.023 14.2 0.1 0.038 13.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 KIK49272.1 - 0.025 14.1 0.1 0.038 13.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KIK49272.1 - 0.047 13.4 0.1 0.073 12.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIK49272.1 - 0.085 13.2 0.1 0.095 13.1 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KIK49272.1 - 0.089 12.7 0.0 7.4 6.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 KIK49272.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE STAS PF01740.21 KIK49272.1 - 0.12 12.0 0.0 0.35 10.5 0.0 1.7 1 1 1 2 2 2 0 STAS domain AAA_33 PF13671.6 KIK49272.1 - 0.13 12.4 0.2 0.22 11.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KIK49272.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Septin DASH_Spc19 PF08287.11 KIK49274.1 - 1.5e-28 99.6 8.2 1.3e-27 96.6 8.2 1.9 1 1 0 1 1 1 1 Spc19 MCM_N PF14551.6 KIK49274.1 - 0.039 14.6 0.2 0.064 13.9 0.2 1.3 1 0 0 1 1 1 0 MCM N-terminal domain Nsp1_C PF05064.13 KIK49274.1 - 0.069 12.9 1.5 0.13 12.1 1.0 1.6 1 1 0 1 1 1 0 Nsp1-like C-terminal region PspB PF06667.12 KIK49274.1 - 2.4 8.3 8.8 6.8 6.8 3.0 2.8 1 1 1 2 2 2 0 Phage shock protein B DUF4140 PF13600.6 KIK49274.1 - 2.7 8.5 8.3 12 6.4 2.7 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Itfg2 PF15907.5 KIK49275.1 - 0.2 10.6 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Integrin-alpha FG-GAP repeat-containing protein 2 F-box-like PF12937.7 KIK49276.1 - 0.15 11.9 2.2 0.53 10.2 1.6 2.2 2 1 0 2 2 2 0 F-box-like DUF1510 PF07423.11 KIK49277.1 - 0.062 13.5 0.3 2.6 8.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1510) MFS_1 PF07690.16 KIK49278.1 - 8.4e-53 179.5 41.4 2e-52 178.3 41.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIK49278.1 - 2.1e-17 62.8 12.7 3.1e-17 62.3 12.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIK49278.1 - 3.8e-13 49.1 13.0 3.8e-13 49.1 13.0 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KIK49278.1 - 0.27 10.0 25.3 0.15 10.8 9.8 2.2 2 0 0 2 2 2 0 MFS_1 like family Utp21 PF04192.12 KIK49279.1 - 1.6e-61 207.8 2.5 2.5e-61 207.2 2.5 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 KIK49279.1 - 5.6e-15 55.4 0.0 0.0012 19.1 0.0 7.4 3 2 6 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK49279.1 - 2.3e-11 44.0 19.4 0.041 14.8 0.0 9.4 10 0 0 10 10 10 3 WD domain, G-beta repeat Hira PF07569.11 KIK49279.1 - 0.00033 20.4 0.8 0.79 9.4 0.1 4.2 2 2 0 3 3 3 1 TUP1-like enhancer of split Nucleoporin_N PF08801.11 KIK49279.1 - 0.0022 16.8 0.2 0.35 9.6 0.0 3.6 3 2 0 3 3 3 1 Nup133 N terminal like Utp12 PF04003.12 KIK49279.1 - 0.0031 17.8 0.6 0.0066 16.7 0.6 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family Cytochrom_D1 PF02239.16 KIK49279.1 - 0.01 14.4 0.1 0.019 13.5 0.1 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KIK49279.1 - 0.12 11.3 0.1 25 3.7 0.0 3.3 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIK49279.1 - 0.17 10.5 1.8 3.3 6.3 0.1 3.1 2 2 1 3 3 3 0 Nucleoporin Nup120/160 Sfi1 PF08457.10 KIK49280.1 - 3.8e-22 78.5 105.1 4.6e-13 48.6 53.4 5.5 1 1 3 4 4 4 4 Sfi1 spindle body protein Rhodanese_C PF12368.8 KIK49281.1 - 3.2 8.2 7.4 2.5 8.6 1.1 2.4 3 0 0 3 3 3 0 Rhodanase C-terminal PIG-Y PF15159.6 KIK49283.1 - 2.1e-18 67.0 6.6 2.3e-18 66.9 6.6 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF2214 PF09980.9 KIK49283.1 - 0.011 15.6 2.2 0.012 15.5 2.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2214) PSI_PsaF PF02507.15 KIK49283.1 - 0.05 13.4 0.3 0.05 13.4 0.3 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III CBM64 PF18666.1 KIK49284.1 - 0.024 14.7 0.2 0.056 13.5 0.2 1.6 1 0 0 1 1 1 0 Carbohydrate-binding module 64 Rx_N PF18052.1 KIK49285.1 - 0.00067 19.9 2.1 0.00079 19.7 2.1 1.1 1 0 0 1 1 1 1 Rx N-terminal domain Sipho_Gp157 PF05565.11 KIK49285.1 - 0.0017 18.4 0.9 0.0018 18.3 0.9 1.0 1 0 0 1 1 1 1 Siphovirus Gp157 SKA2 PF16740.5 KIK49285.1 - 0.0038 17.0 2.4 0.0045 16.8 2.4 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 UPF0242 PF06785.11 KIK49285.1 - 0.0069 16.5 1.4 0.007 16.5 1.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus C2-set PF05790.15 KIK49285.1 - 0.015 15.5 0.3 0.023 14.9 0.3 1.5 1 1 0 1 1 1 0 Immunoglobulin C2-set domain HALZ PF02183.18 KIK49285.1 - 0.018 15.2 1.1 0.032 14.4 1.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Fungal_TACC PF12709.7 KIK49285.1 - 0.044 14.2 2.6 0.059 13.8 2.6 1.2 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins DivIC PF04977.15 KIK49285.1 - 0.049 13.4 1.5 0.065 13.0 1.5 1.3 1 0 0 1 1 1 0 Septum formation initiator HTH_37 PF13744.6 KIK49285.1 - 0.051 13.5 1.1 0.065 13.2 1.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Matrilin_ccoil PF10393.9 KIK49285.1 - 0.055 13.3 1.6 0.079 12.8 1.6 1.3 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin TMEM192 PF14802.6 KIK49285.1 - 0.065 12.3 0.0 0.068 12.3 0.0 1.0 1 0 0 1 1 1 0 TMEM192 family DUF5320 PF17253.2 KIK49285.1 - 0.23 12.6 0.8 0.25 12.4 0.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5320) ox_reductase_C PF08635.10 KIK49286.1 - 2.1e-71 238.1 0.2 3.3e-71 237.5 0.2 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 KIK49286.1 - 1.2e-24 87.4 0.9 6.2e-24 85.1 0.0 2.4 3 0 0 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIK49286.1 - 0.0025 17.8 0.0 0.0042 17.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 KIK49287.1 - 1.8e-19 70.7 0.0 3.2e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold B12-binding_2 PF02607.17 KIK49287.1 - 0.026 15.0 0.0 0.082 13.4 0.0 1.8 1 0 0 1 1 1 0 B12 binding domain Polysacc_deac_2 PF04748.13 KIK49287.1 - 0.066 12.4 0.1 0.33 10.1 0.1 1.9 1 1 1 2 2 2 0 Divergent polysaccharide deacetylase zf-C2HE PF16278.5 KIK49288.1 - 3.3e-17 62.7 1.4 3.3e-17 62.7 1.4 2.2 3 0 0 3 3 3 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 KIK49288.1 - 4.4e-15 56.1 0.1 7.3e-15 55.4 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KIK49288.1 - 2.8e-12 47.2 0.1 6.1e-12 46.1 0.0 1.6 2 0 0 2 2 2 1 HIT domain Dynein_light PF01221.18 KIK49288.1 - 0.11 12.9 0.1 0.38 11.1 0.0 1.9 2 0 0 2 2 2 0 Dynein light chain type 1 SET PF00856.28 KIK49289.1 - 1.9e-10 41.4 0.0 6.8e-10 39.6 0.0 1.9 1 1 0 1 1 1 1 SET domain preSET_CXC PF18264.1 KIK49289.1 - 4e-05 24.0 20.9 4e-05 24.0 20.9 3.3 1 1 1 2 2 2 1 CXC domain RabGAP-TBC PF00566.18 KIK49290.1 - 5.3e-43 147.2 4.9 3.7e-41 141.1 4.9 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KIK49290.1 - 2.5e-05 23.8 0.0 0.00071 19.1 0.0 2.4 2 0 0 2 2 2 1 Rab-binding domain (RBD) Ribosomal_S21e PF01249.18 KIK49291.1 - 9.7e-41 137.8 0.1 1.1e-40 137.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e GP63 PF17471.2 KIK49293.1 - 0.094 12.9 0.2 0.15 12.3 0.1 1.6 1 1 1 2 2 2 0 Gene product 63 HSP90 PF00183.18 KIK49294.1 - 2.7e-227 755.8 27.0 3.4e-227 755.5 27.0 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KIK49294.1 - 6.7e-14 52.4 0.0 1.3e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KIK49294.1 - 6.2e-10 39.0 0.1 1.8e-09 37.5 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HBS1_N PF08938.10 KIK49294.1 - 0.015 15.6 1.3 0.015 15.6 1.3 3.1 2 0 0 2 2 2 0 HBS1 N-terminus Cofac_haem_bdg PF04187.13 KIK49294.1 - 0.069 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN Peptidase_C37 PF05416.12 KIK49294.1 - 0.62 8.5 10.6 0.18 10.3 0.1 2.2 2 0 0 2 2 2 0 Southampton virus-type processing peptidase Thr_synth_N PF14821.6 KIK49295.1 - 8.1e-26 90.0 0.0 3.4e-25 88.1 0.0 2.1 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 KIK49295.1 - 7.8e-16 58.3 0.0 2.2e-15 56.8 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HMMR_N PF15905.5 KIK49297.1 - 2.1e-05 24.2 16.9 2.1e-05 24.2 16.9 1.6 1 1 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal ALIX_LYPXL_bnd PF13949.6 KIK49297.1 - 0.13 11.6 18.0 0.18 11.1 16.5 1.9 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV ADIP PF11559.8 KIK49297.1 - 0.24 11.5 25.3 0.1 12.7 9.5 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 KIK49297.1 - 0.24 11.6 8.9 0.57 10.4 1.5 3.1 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KIK49297.1 - 2 8.5 8.6 0.72 9.9 2.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 KIK49297.1 - 2.5 8.4 6.8 41 4.5 1.0 3.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) ISG65-75 PF11727.8 KIK49297.1 - 2.7 7.1 14.8 3.8 6.7 1.6 2.3 1 1 0 2 2 2 0 Invariant surface glycoprotein HAUS-augmin3 PF14932.6 KIK49297.1 - 2.8 7.5 17.6 0.02 14.5 4.3 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 GAS PF13851.6 KIK49297.1 - 3 7.1 21.9 0.76 9.1 11.7 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding zf-CpG_bind_C PF12269.8 KIK49297.1 - 3.2 7.5 9.5 2.1 8.1 1.8 2.3 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain DUF3584 PF12128.8 KIK49297.1 - 4.6 4.6 24.3 9.3 3.6 24.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4795 PF16043.5 KIK49297.1 - 4.6 6.8 16.4 80 2.7 16.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) AAA_13 PF13166.6 KIK49297.1 - 4.6 5.7 17.5 8.6 4.9 17.5 1.3 1 1 0 1 1 1 0 AAA domain DUF4407 PF14362.6 KIK49297.1 - 5.4 6.3 20.7 10 5.4 19.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) SlyX PF04102.12 KIK49297.1 - 6.3 7.5 15.8 3.4 8.4 3.2 3.7 3 1 0 3 3 3 0 SlyX TPR_MLP1_2 PF07926.12 KIK49297.1 - 6.8 6.8 27.0 8.8 6.4 3.6 3.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KIK49297.1 - 7.8 5.3 25.9 5 5.9 13.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3450 PF11932.8 KIK49297.1 - 9.5 5.4 18.0 1.9 7.7 6.6 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF2730 PF10805.8 KIK49297.1 - 9.6 6.4 7.6 19 5.4 0.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) ERM PF00769.19 KIK49297.1 - 9.7 5.9 35.6 73 3.0 34.3 2.5 1 1 2 3 3 3 0 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.12 KIK49299.1 - 0.0062 16.6 40.4 1.2 9.2 17.1 3.6 2 1 1 3 3 3 3 TPR/MLP1/MLP2-like protein DHR10 PF18595.1 KIK49299.1 - 0.0071 16.4 36.3 0.035 14.2 9.0 3.7 2 1 1 3 3 3 2 Designed helical repeat protein 10 domain SesA PF17107.5 KIK49299.1 - 0.23 11.7 4.7 0.073 13.3 0.6 2.3 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Spc7 PF08317.11 KIK49299.1 - 0.94 8.3 38.5 0.32 9.8 10.1 3.3 2 1 2 4 4 4 0 Spc7 kinetochore protein Sec34 PF04136.15 KIK49299.1 - 1.5 8.7 16.6 0.45 10.4 4.2 3.5 2 1 2 4 4 4 0 Sec34-like family KASH_CCD PF14662.6 KIK49299.1 - 4.3 7.1 33.0 0.91 9.3 12.0 2.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Occludin_ELL PF07303.13 KIK49299.1 - 4.9 7.9 22.2 3.1 8.6 1.4 3.4 2 1 1 3 3 3 0 Occludin homology domain Fib_alpha PF08702.10 KIK49299.1 - 6.9 6.8 16.1 7 6.8 5.8 2.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 KIK49299.1 - 8 6.9 34.8 1.6 9.1 11.3 2.8 1 1 3 4 4 4 0 Fez1 Cauli_AT PF03233.13 KIK49299.1 - 8.3 6.3 7.2 5.5 6.9 2.6 2.5 1 1 2 3 3 3 0 Aphid transmission protein DUF1264 PF06884.11 KIK49300.1 - 1.1e-16 60.9 0.0 1.3e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) DUF4636 PF15468.6 KIK49300.1 - 0.094 12.4 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) DUF1264 PF06884.11 KIK49301.1 - 7e-12 45.3 2.7 9.8e-12 44.8 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) NAC PF01849.18 KIK49302.1 - 2.7e-19 68.9 0.0 4.7e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 NAC domain UBA_4 PF14555.6 KIK49302.1 - 0.052 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Methyltransf_11 PF08241.12 KIK49303.1 - 6.5e-06 26.7 0.0 1.1e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK49303.1 - 9.7e-06 26.2 0.0 2.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK49303.1 - 0.0062 16.4 0.0 0.0093 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIK49303.1 - 0.0067 16.2 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIK49303.1 - 0.033 14.9 0.0 0.058 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Glyco_tran_28_C PF04101.16 KIK49304.1 - 1.8e-28 99.6 0.0 2.1e-28 99.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain P5CR_dimer PF14748.6 KIK49305.1 - 1.3e-38 131.4 3.6 3.4e-38 130.0 3.0 1.9 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KIK49305.1 - 7e-13 49.0 0.2 7.5e-10 39.3 0.0 2.5 1 1 1 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent AAA PF00004.29 KIK49306.1 - 2.3e-44 151.0 0.1 7.7e-44 149.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KIK49306.1 - 1.3e-09 37.9 0.1 7.5e-09 35.4 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KIK49306.1 - 4.8e-08 33.6 0.2 3.4e-05 24.3 0.0 3.0 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KIK49306.1 - 5e-08 33.0 0.1 1.7e-07 31.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIK49306.1 - 1.2e-07 32.0 0.0 3e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KIK49306.1 - 4.4e-06 26.0 0.0 8.2e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 KIK49306.1 - 0.00016 22.0 0.0 0.0011 19.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KIK49306.1 - 0.00018 22.0 0.0 0.0024 18.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 KIK49306.1 - 0.00049 20.1 0.1 0.019 14.9 0.0 2.7 3 0 0 3 3 3 1 NTPase AAA_22 PF13401.6 KIK49306.1 - 0.00062 20.1 4.3 0.013 15.8 0.0 3.0 3 1 1 4 4 2 1 AAA domain RuvB_N PF05496.12 KIK49306.1 - 0.00068 19.4 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KIK49306.1 - 0.00073 19.6 0.0 0.003 17.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 KIK49306.1 - 0.0008 19.4 0.0 0.014 15.4 0.0 2.4 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KIK49306.1 - 0.0022 18.3 0.0 0.0056 17.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase CENP-F_leu_zip PF10473.9 KIK49306.1 - 0.0024 17.9 1.1 0.0039 17.2 1.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_30 PF13604.6 KIK49306.1 - 0.0027 17.4 0.4 0.0073 16.0 0.4 1.8 1 1 0 1 1 1 1 AAA domain AAA_lid_3 PF17862.1 KIK49306.1 - 0.0039 17.0 0.0 0.0098 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_7 PF12775.7 KIK49306.1 - 0.0044 16.6 0.1 0.031 13.8 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 KIK49306.1 - 0.0044 16.3 0.0 0.0091 15.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KIK49306.1 - 0.0044 17.2 0.0 0.017 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KIK49306.1 - 0.0059 16.4 0.7 0.018 14.8 0.0 2.2 3 0 0 3 3 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KIK49306.1 - 0.0095 15.3 0.1 0.021 14.2 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KIK49306.1 - 0.013 15.4 0.1 0.094 12.6 0.1 2.1 2 0 0 2 2 2 0 NACHT domain TniB PF05621.11 KIK49306.1 - 0.014 14.8 0.0 0.63 9.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_25 PF13481.6 KIK49306.1 - 0.014 14.9 0.4 0.064 12.8 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA_3 PF07726.11 KIK49306.1 - 0.016 15.0 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KIK49306.1 - 0.021 14.6 0.1 0.041 13.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KIK49306.1 - 0.045 13.5 0.2 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KIK49306.1 - 0.049 14.0 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 KIK49306.1 - 0.065 12.1 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 AFG1-like ATPase Sigma54_activat PF00158.26 KIK49306.1 - 0.09 12.5 0.3 1.3 8.7 0.0 2.7 3 1 0 3 3 3 0 Sigma-54 interaction domain Bac_DnaA PF00308.18 KIK49306.1 - 0.099 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein ATPase PF06745.13 KIK49306.1 - 0.14 11.4 0.7 0.55 9.5 0.0 2.2 3 0 0 3 3 3 0 KaiC ATPase_2 PF01637.18 KIK49306.1 - 0.15 11.9 1.7 0.79 9.6 0.0 2.8 3 1 1 4 4 3 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 KIK49306.1 - 0.16 11.0 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RRM_1 PF00076.22 KIK49307.1 - 3.8e-11 42.7 0.0 1e-10 41.2 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 4HBT PF03061.22 KIK49308.1 - 0.0033 17.8 0.3 0.16 12.3 0.0 2.5 2 1 0 2 2 2 2 Thioesterase superfamily SNRNP27 PF08648.12 KIK49309.1 - 5.5e-30 103.2 0.3 8.5e-30 102.6 0.3 1.3 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins SUI1 PF01253.22 KIK49310.1 - 1.5e-28 99.1 0.2 1.9e-28 98.8 0.2 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 rRNA_processing PF08524.11 KIK49311.1 - 0.26 11.3 14.2 6.1 6.9 14.2 2.6 1 1 0 1 1 1 0 rRNA processing PPP4R2 PF09184.11 KIK49312.1 - 7.3e-19 68.4 0.0 8.1e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 PPP4R2 PAP2 PF01569.21 KIK49313.1 - 8.5e-29 100.1 4.0 1.9e-28 98.9 4.0 1.5 1 0 0 1 1 1 1 PAP2 superfamily DUF5510 PF17629.2 KIK49313.1 - 0.06 13.3 2.7 0.098 12.6 0.0 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5510) DUF2070 PF09843.9 KIK49313.1 - 0.15 10.3 1.2 0.26 9.5 1.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3087 PF11286.8 KIK49313.1 - 0.74 9.3 1.9 2.4 7.6 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Aminotran_5 PF00266.19 KIK49314.1 - 1.4e-38 132.8 0.0 1.7e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Methyltransf_16 PF10294.9 KIK49315.1 - 9.2e-19 67.8 0.4 5.6e-14 52.2 0.3 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 KIK49315.1 - 0.006 16.4 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KIK49315.1 - 0.024 14.0 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_11 PF08241.12 KIK49315.1 - 0.03 14.9 0.0 0.24 12.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 KIK49315.1 - 0.037 14.7 0.2 0.17 12.6 0.1 2.0 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KIK49315.1 - 0.1 12.1 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KIK49315.1 - 0.16 11.3 0.2 0.24 10.8 0.2 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) EF_assoc_2 PF08356.12 KIK49316.1 - 0.036 14.1 0.1 0.059 13.4 0.1 1.3 1 0 0 1 1 1 0 EF hand associated EF-hand_7 PF13499.6 KIK49316.1 - 0.075 13.5 0.1 0.12 12.8 0.1 1.5 1 1 0 1 1 1 0 EF-hand domain pair EF_assoc_1 PF08355.12 KIK49316.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 EF hand associated DEAD PF00270.29 KIK49317.1 - 6e-46 156.4 0.0 3.3e-45 154.0 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK49317.1 - 1.2e-28 99.7 0.0 4.8e-28 97.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK49317.1 - 0.00047 20.2 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UnbV_ASPIC PF07593.12 KIK49318.1 - 0.092 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 ASPIC and UnbV Pkinase PF00069.25 KIK49319.1 - 1.4e-39 136.0 0.0 1.7e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK49319.1 - 2e-20 73.2 0.0 3.7e-20 72.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK49319.1 - 0.0012 18.9 0.6 0.01 15.8 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KIK49319.1 - 0.0016 18.1 0.0 0.59 9.7 0.0 2.1 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KIK49319.1 - 0.0081 15.5 0.0 0.086 12.1 0.1 2.3 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 KIK49319.1 - 0.055 12.8 0.1 0.093 12.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIK49319.1 - 0.16 10.8 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain PRKCSH PF07915.13 KIK49321.1 - 8.1e-11 42.8 0.7 1.7e-10 41.7 0.0 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KIK49321.1 - 0.00094 18.9 0.1 0.0038 16.9 0.1 1.9 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein AT_hook PF02178.19 KIK49322.1 - 2.6e-06 26.6 51.7 0.016 15.0 5.6 4.5 4 0 0 4 4 4 4 AT hook motif CDC27 PF09507.10 KIK49322.1 - 2.6 7.4 19.8 3.3 7.0 19.8 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FAD_binding_3 PF01494.19 KIK49323.1 - 1.2e-20 74.1 0.0 1.7e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIK49323.1 - 7.9e-06 25.3 0.0 3.3e-05 23.3 0.0 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIK49323.1 - 8.3e-05 22.3 0.1 0.00018 21.2 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIK49323.1 - 8.3e-05 23.1 0.0 0.0002 21.9 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIK49323.1 - 0.00016 21.9 0.1 0.00031 20.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KIK49323.1 - 0.00044 19.4 0.1 0.0006 19.0 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KIK49323.1 - 0.0015 17.3 0.0 0.0022 16.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KIK49323.1 - 0.0032 16.8 0.1 0.0054 16.0 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KIK49323.1 - 0.0075 15.5 0.1 0.27 10.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KIK49323.1 - 0.015 14.7 0.1 0.026 13.9 0.0 1.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIK49323.1 - 0.019 14.1 0.3 0.028 13.5 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain SE PF08491.10 KIK49323.1 - 0.027 13.5 0.0 0.24 10.4 0.0 2.1 1 1 0 1 1 1 0 Squalene epoxidase 3HCDH_N PF02737.18 KIK49323.1 - 0.027 14.4 0.1 0.043 13.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 KIK49323.1 - 0.079 13.5 0.1 0.25 11.8 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain Pyr_redox_3 PF13738.6 KIK49323.1 - 0.13 11.5 0.1 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIK49323.1 - 0.13 11.0 0.1 1.3 7.8 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Aminotran_5 PF00266.19 KIK49324.1 - 2.1e-12 46.7 0.0 3e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Abhydrolase_3 PF07859.13 KIK49325.1 - 1.3e-10 41.5 0.0 1.8e-10 41.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIK49325.1 - 0.0036 16.8 0.0 1.2 8.5 0.0 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KIK49325.1 - 0.0048 16.2 0.2 0.9 8.8 0.0 2.5 2 1 0 2 2 2 2 Serine aminopeptidase, S33 COesterase PF00135.28 KIK49325.1 - 0.013 14.4 0.0 1.9 7.3 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Pmp3 PF01679.17 KIK49326.1 - 3e-16 59.4 0.5 3.2e-16 59.3 0.5 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Hexapep PF00132.24 KIK49327.1 - 4.4e-11 42.0 12.4 2.5e-05 23.8 0.8 4.4 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) W2 PF02020.18 KIK49327.1 - 4.1e-10 39.6 0.1 4.1e-10 39.6 0.1 2.3 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.23 KIK49327.1 - 5.5e-08 32.7 0.0 8.8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.12 KIK49327.1 - 1.6e-05 24.1 0.3 2.9e-05 23.2 0.3 1.4 1 0 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.7 KIK49327.1 - 0.00032 21.1 0.0 0.00062 20.2 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KIK49327.1 - 0.0092 15.7 1.5 0.0092 15.7 1.5 4.1 2 1 2 4 4 4 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KIK49327.1 - 0.093 10.8 3.3 1.5 6.9 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) Ndc1_Nup PF09531.10 KIK49328.1 - 7.9 5.0 17.0 11 4.5 17.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Methyltr_RsmB-F PF01189.17 KIK49329.1 - 4.7e-76 254.9 0.0 7.7e-76 254.2 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KIK49329.1 - 1.5e-05 25.4 0.5 0.00046 20.6 0.2 2.8 2 1 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 KIK49329.1 - 0.00032 20.5 0.0 0.00062 19.6 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 KIK49329.1 - 0.0033 17.2 0.0 0.0054 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KIK49329.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KIK49329.1 - 0.072 13.8 0.0 0.24 12.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 KIK49329.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Fibrillarin PF01269.17 KIK49329.1 - 0.14 11.3 0.0 0.64 9.1 0.0 1.9 2 0 0 2 2 2 0 Fibrillarin FUN14 PF04930.15 KIK49330.1 - 4e-19 68.8 0.7 4e-19 68.8 0.7 1.5 2 0 0 2 2 2 1 FUN14 family DUF2613 PF11021.8 KIK49330.1 - 2.5 8.3 4.8 15 5.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) NdhL PF10716.9 KIK49331.1 - 0.11 12.5 4.4 0.28 11.2 4.4 1.7 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit Chlorovi_GP_rpt PF06598.11 KIK49331.1 - 0.18 11.9 0.2 0.35 11.0 0.2 1.4 1 0 0 1 1 1 0 Chlorovirus glycoprotein repeat Peptidase_U4 PF03419.13 KIK49331.1 - 2 7.7 6.8 2.8 7.1 6.8 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Ion_trans PF00520.31 KIK49332.1 - 0.00021 20.6 0.9 0.00029 20.2 0.9 1.1 1 0 0 1 1 1 1 Ion transport protein PspA_IM30 PF04012.12 KIK49332.1 - 0.074 12.6 0.5 0.098 12.2 0.5 1.1 1 0 0 1 1 1 0 PspA/IM30 family DASH_Dad4 PF08650.10 KIK49334.1 - 7.1e-25 86.8 0.7 7.7e-25 86.7 0.7 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 HEAT PF02985.22 KIK49336.1 - 1.1e-14 53.3 10.8 0.022 15.0 0.1 8.6 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.6 KIK49336.1 - 2.2e-09 37.5 15.6 0.0029 18.0 0.1 6.4 5 2 3 8 8 8 5 HEAT repeats HEAT_EZ PF13513.6 KIK49336.1 - 0.0082 16.6 7.3 1 10.0 0.2 4.8 4 1 1 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 KIK49336.1 - 0.024 14.7 0.0 35 4.4 0.0 3.9 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 zf-AN1 PF01428.16 KIK49339.1 - 2.8e-10 40.2 6.4 2.8e-10 40.2 6.4 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger Rubredoxin_2 PF18073.1 KIK49339.1 - 0.013 15.3 0.8 0.013 15.3 0.8 2.2 2 1 0 2 2 2 0 Rubredoxin metal binding domain IBR PF01485.21 KIK49339.1 - 0.28 11.4 8.2 0.38 11.0 7.6 1.6 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Lyase_1 PF00206.20 KIK49341.1 - 7.7e-97 324.4 0.0 1.1e-96 324.0 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KIK49341.1 - 1.8e-23 83.1 0.1 4.4e-23 81.8 0.1 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Cyanate_lyase PF02560.14 KIK49341.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Cyanate lyase C-terminal domain Syntaxin PF00804.25 KIK49342.1 - 8.7e-34 117.0 12.4 8.7e-34 117.0 12.4 1.6 1 1 0 1 1 1 1 Syntaxin Syntaxin_2 PF14523.6 KIK49342.1 - 8e-09 35.8 17.5 9.8e-09 35.5 8.3 2.2 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KIK49342.1 - 2.3e-08 33.9 6.1 1.7e-07 31.1 6.1 2.4 1 1 0 1 1 1 1 SNARE domain SKA1 PF07160.12 KIK49342.1 - 0.0049 16.7 2.2 0.0049 16.7 2.2 2.6 1 1 0 2 2 2 1 Spindle and kinetochore-associated protein 1 Use1 PF09753.9 KIK49342.1 - 0.005 16.6 11.7 0.0054 16.5 9.9 1.6 1 1 1 2 2 2 1 Membrane fusion protein Use1 BLOC1_2 PF10046.9 KIK49342.1 - 0.0071 16.6 11.3 0.58 10.5 0.0 3.9 3 2 1 4 4 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5383 PF17355.2 KIK49342.1 - 0.0076 16.6 0.7 0.0076 16.6 0.7 1.8 2 0 0 2 2 1 1 Family of unknown function (DUF5383) DUF745 PF05335.13 KIK49342.1 - 0.011 15.5 10.8 0.02 14.6 2.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF745) DUF1659 PF07872.11 KIK49342.1 - 0.011 15.4 0.1 0.45 10.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1659) VitD-bind_III PF09164.10 KIK49342.1 - 0.011 15.6 0.5 0.055 13.5 0.1 2.1 2 0 0 2 2 2 0 Vitamin D binding protein, domain III Laminin_II PF06009.12 KIK49342.1 - 0.013 15.5 10.7 0.09 12.8 0.4 2.7 3 0 0 3 3 3 0 Laminin Domain II MCPsignal PF00015.21 KIK49342.1 - 0.023 14.5 2.9 0.023 14.5 2.9 2.8 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4064 PF13273.6 KIK49342.1 - 0.025 14.9 0.2 0.057 13.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DASH_Dam1 PF08653.10 KIK49342.1 - 0.063 13.1 2.6 0.38 10.6 0.1 3.0 3 0 0 3 3 3 0 DASH complex subunit Dam1 Spectrin PF00435.21 KIK49342.1 - 0.073 13.6 7.9 0.61 10.6 0.1 3.0 3 1 0 3 3 3 0 Spectrin repeat Ycf34 PF10718.9 KIK49342.1 - 0.074 13.8 0.3 0.76 10.5 0.0 2.3 2 0 0 2 2 2 0 Hypothetical chloroplast protein Ycf34 BatA PF07584.11 KIK49342.1 - 0.11 12.8 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Tweety PF04906.13 KIK49342.1 - 0.14 10.8 7.4 0.065 11.9 0.9 2.2 2 1 0 2 2 2 0 Tweety Synaptobrevin PF00957.21 KIK49342.1 - 0.27 11.1 11.7 0.31 10.9 3.6 2.9 2 1 0 2 2 2 0 Synaptobrevin PCRF PF03462.18 KIK49342.1 - 0.74 9.7 14.0 0.39 10.6 2.9 2.7 1 1 1 3 3 3 0 PCRF domain EMP24_GP25L PF01105.24 KIK49342.1 - 1 9.3 10.8 0.083 12.8 2.1 3.0 1 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD ABC_tran_CTD PF16326.5 KIK49342.1 - 1.5 9.1 12.9 0.073 13.3 2.8 3.0 3 0 0 3 3 3 0 ABC transporter C-terminal domain DUF16 PF01519.16 KIK49342.1 - 2 8.9 14.3 43 4.7 14.4 2.8 1 1 0 1 1 1 0 Protein of unknown function DUF16 COG2 PF06148.11 KIK49342.1 - 3 7.9 10.8 0.88 9.7 0.2 3.4 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 RP-C_C PF11800.8 KIK49342.1 - 5.5 7.0 10.1 5.5 7.0 1.3 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region LMBR1 PF04791.16 KIK49342.1 - 9.4 5.0 12.4 30 3.3 12.4 1.7 1 1 0 1 1 1 0 LMBR1-like membrane protein MFS_1 PF07690.16 KIK49343.1 - 9.4e-15 54.4 27.1 9.4e-15 54.4 27.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KIK49343.1 - 8.4e-12 45.1 1.0 8.4e-12 45.1 1.0 2.0 2 0 0 2 2 2 1 Nodulin-like Ist1 PF03398.14 KIK49345.1 - 4.6e-32 111.2 0.2 6.6e-32 110.7 0.2 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RabGAP-TBC PF00566.18 KIK49345.1 - 1.4e-11 44.4 0.1 5.1e-09 36.1 0.0 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Nop14 PF04147.12 KIK49345.1 - 1 7.5 6.1 1.9 6.6 6.1 1.3 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KIK49345.1 - 5.2 5.1 8.6 9.2 4.2 8.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi PIG-H PF10181.9 KIK49346.1 - 1.4e-15 56.9 0.0 2.1e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component 2OG-FeII_Oxy_3 PF13640.6 KIK49347.1 - 7.7e-08 33.1 0.0 1.3e-07 32.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DEAD PF00270.29 KIK49348.1 - 2.9e-49 167.2 0.0 5.4e-49 166.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIK49348.1 - 9.1e-30 103.3 0.0 3.3e-29 101.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIK49348.1 - 1.2e-07 31.8 0.0 2.4e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KIK49348.1 - 0.00039 20.2 0.0 0.0018 18.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIK49348.1 - 0.029 14.7 0.0 0.27 11.5 0.0 2.5 1 1 0 1 1 1 0 AAA domain TRAPPC10 PF12584.8 KIK49349.1 - 4.4e-29 101.2 0.0 9.7e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 ALG3 PF05208.13 KIK49350.1 - 2.3e-138 461.5 7.7 2.7e-138 461.3 7.7 1.0 1 0 0 1 1 1 1 ALG3 protein DUF2070 PF09843.9 KIK49350.1 - 8.8 4.5 7.9 16 3.6 7.9 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RhoGEF PF00621.20 KIK49352.1 - 6.8e-20 72.1 0.1 1.6e-14 54.5 0.1 2.2 2 0 0 2 2 2 2 RhoGEF domain DUF3915 PF13054.6 KIK49352.1 - 3.4 7.7 6.1 3.5 7.6 3.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Asn_synthase PF00733.21 KIK49353.1 - 6.5e-94 315.5 0.2 1e-55 189.9 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KIK49353.1 - 1.2e-34 118.9 0.0 1.9e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KIK49353.1 - 1.4e-28 99.8 0.0 2.4e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain QueC PF06508.13 KIK49353.1 - 0.02 14.4 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 KIK49353.1 - 0.069 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD synthase DUF3700 PF12481.8 KIK49353.1 - 0.088 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Aluminium induced protein PIG-U PF06728.13 KIK49354.1 - 0.12 11.4 1.2 0.13 11.3 1.2 1.0 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U Far-17a_AIG1 PF04750.14 KIK49355.1 - 2.9e-29 101.9 6.6 3.2e-29 101.7 6.6 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Aldo_ket_red PF00248.21 KIK49356.1 - 1.7e-53 181.8 0.0 1.9e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CDP-OH_P_transf PF01066.21 KIK49357.1 - 1.5e-13 51.3 0.5 1.5e-13 51.3 0.5 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Syntaxin PF00804.25 KIK49358.1 - 5.4e-29 101.3 2.3 8.7e-29 100.6 2.3 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KIK49358.1 - 7.1e-10 38.7 2.2 1.4e-09 37.8 0.1 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 KIK49358.1 - 5.2e-05 23.5 4.4 7.8e-05 23.0 2.0 2.0 2 0 0 2 2 2 1 Syntaxin-like protein BLOC1_2 PF10046.9 KIK49358.1 - 0.021 15.1 2.1 0.28 11.5 0.1 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SKA1 PF07160.12 KIK49358.1 - 0.021 14.7 0.9 0.75 9.6 0.1 2.3 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 NAP PF00956.18 KIK49358.1 - 0.027 13.7 1.1 0.035 13.3 0.1 1.7 2 0 0 2 2 2 0 Nucleosome assembly protein (NAP) Synaptobrevin PF00957.21 KIK49358.1 - 0.068 13.0 0.8 0.68 9.8 0.0 2.6 2 1 0 2 2 2 0 Synaptobrevin PhaP_Bmeg PF09602.10 KIK49358.1 - 0.071 13.0 2.0 0.37 10.7 0.2 2.1 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) VitD-bind_III PF09164.10 KIK49358.1 - 0.083 12.9 0.0 0.73 9.9 0.0 2.1 2 0 0 2 2 2 0 Vitamin D binding protein, domain III APG17 PF04108.12 KIK49358.1 - 0.085 12.0 11.1 0.7 8.9 0.1 3.0 2 1 1 3 3 3 0 Autophagy protein Apg17 Baculo_PEP_C PF04513.12 KIK49358.1 - 0.11 12.5 1.8 1 9.4 0.3 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_export PF16962.5 KIK49358.1 - 0.19 10.1 0.0 0.25 9.7 0.0 1.1 1 0 0 1 1 1 0 Putative ABC exporter TMF_TATA_bd PF12325.8 KIK49358.1 - 0.25 11.6 3.5 1.1 9.4 0.2 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding V-SNARE PF05008.15 KIK49358.1 - 0.26 11.7 0.1 0.26 11.7 0.1 2.7 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DASH_Dam1 PF08653.10 KIK49358.1 - 0.52 10.2 2.4 7.8 6.4 0.1 2.9 2 1 1 3 3 3 0 DASH complex subunit Dam1 Spectrin PF00435.21 KIK49358.1 - 1.1 9.8 9.7 0.58 10.7 0.5 3.0 3 1 0 3 3 3 0 Spectrin repeat NPV_P10 PF05531.12 KIK49358.1 - 3.2 8.3 7.8 16 6.1 0.0 3.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein HisKA PF00512.25 KIK49358.1 - 3.5 7.7 10.0 2.8 8.0 0.2 3.4 4 0 0 4 4 4 0 His Kinase A (phospho-acceptor) domain HAUS-augmin3 PF14932.6 KIK49358.1 - 8.3 5.9 7.9 1.2 8.7 0.8 2.3 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 AAA PF00004.29 KIK49359.1 - 2.3e-35 121.9 0.0 8.7e-35 120.0 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIK49359.1 - 4e-09 36.1 0.0 1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KIK49359.1 - 6e-06 26.7 0.1 0.0067 16.8 0.0 4.3 5 0 0 5 5 5 1 AAA ATPase domain AAA_22 PF13401.6 KIK49359.1 - 0.00052 20.3 0.2 0.037 14.3 0.0 3.3 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 KIK49359.1 - 0.0025 18.0 0.0 0.0091 16.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KIK49359.1 - 0.0063 16.5 0.1 0.025 14.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_6 PF12774.7 KIK49359.1 - 0.0064 15.5 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 KIK49359.1 - 0.0069 16.9 0.1 0.051 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KIK49359.1 - 0.025 14.6 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 KIK49359.1 - 0.036 13.9 0.2 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KIK49359.1 - 0.047 13.4 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KIK49359.1 - 0.064 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KIK49359.1 - 0.085 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 KIK49359.1 - 0.087 13.1 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KIK49359.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_19 PF13245.6 KIK49359.1 - 0.18 12.1 0.1 0.49 10.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIK49359.1 - 0.2 12.1 0.0 0.44 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KIK49359.1 - 0.21 11.3 0.0 1.3 8.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain SMC_Nse1 PF07574.13 KIK49360.1 - 3.9e-30 105.2 1.1 3.9e-30 105.2 1.1 2.8 2 1 0 2 2 2 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KIK49360.1 - 6.1e-09 36.0 13.6 1.1e-08 35.2 13.6 1.4 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 KIK49360.1 - 0.00049 20.4 11.7 0.00096 19.4 11.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H PF13771.6 KIK49360.1 - 0.0066 16.7 6.8 0.017 15.3 6.8 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-C3HC4_2 PF13923.6 KIK49360.1 - 0.065 13.1 11.0 0.13 12.1 11.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK49360.1 - 1.2 9.1 15.0 2 8.4 15.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIK49360.1 - 2.7 7.8 8.0 6.4 6.6 8.0 1.7 1 0 0 1 1 1 0 RING-like zinc finger CDC27 PF09507.10 KIK49360.1 - 3.5 6.9 20.7 4.9 6.4 20.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDP-OH_P_transf PF01066.21 KIK49361.1 - 1.7e-12 47.9 0.7 6.3e-12 46.1 0.9 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DNA_primase_lrg PF04104.14 KIK49362.1 - 1e-86 290.6 0.0 1.6e-86 290.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DUF2076 PF09849.9 KIK49363.1 - 4.9 7.1 9.5 0.21 11.6 3.0 1.9 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) USP7_ICP0_bdg PF12436.8 KIK49365.1 - 8.3e-86 287.2 0.1 5e-84 281.4 0.1 3.3 2 2 2 4 4 4 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KIK49365.1 - 5.2e-70 235.4 1.5 3.5e-65 219.6 0.1 2.8 2 1 0 2 2 2 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 KIK49365.1 - 6.6e-51 173.3 0.2 1e-50 172.7 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIK49365.1 - 5.1e-21 75.6 0.1 1.6e-20 74.0 0.0 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KIK49365.1 - 2.4e-08 34.1 0.0 1.5e-07 31.6 0.0 2.4 1 0 0 1 1 1 1 MATH domain UN_NPL4 PF11543.8 KIK49365.1 - 0.03 14.8 0.2 14 6.2 0.1 3.9 4 0 0 4 4 4 0 Nuclear pore localisation protein NPL4 ubiquitin PF00240.23 KIK49365.1 - 0.03 14.1 0.7 8 6.3 0.0 4.3 5 0 0 5 5 5 0 Ubiquitin family Sec66 PF09802.9 KIK49366.1 - 2.1e-57 193.6 0.0 2.6e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Citrate_synt PF00285.21 KIK49367.1 - 8.9e-102 340.8 0.0 1.1e-101 340.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF2269 PF10027.9 KIK49367.1 - 0.092 12.8 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) B56 PF01603.20 KIK49369.1 - 3e-185 616.1 6.8 3.6e-185 615.8 6.8 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF1180 PF06679.12 KIK49369.1 - 5.4 7.4 7.8 9 6.7 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) HSP70 PF00012.20 KIK49370.1 - 6.1e-263 873.5 2.3 6.9e-263 873.3 2.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIK49370.1 - 5.9e-15 54.9 0.0 7.5e-14 51.3 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KIK49370.1 - 0.0029 17.3 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 KIK49370.1 - 0.047 12.9 0.1 0.11 11.7 0.1 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Bacteriocin_IIc PF10439.9 KIK49370.1 - 0.18 11.9 3.7 0.41 10.8 3.7 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide RabGAP-TBC PF00566.18 KIK49371.1 - 2.1e-28 99.5 0.2 1.7e-27 96.5 0.2 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain SOGA PF11365.8 KIK49371.1 - 0.36 12.0 4.5 0.27 12.4 2.4 1.9 1 1 1 2 2 2 0 Protein SOGA FAD_binding_2 PF00890.24 KIK49372.1 - 1.8e-126 422.6 2.7 2.3e-126 422.2 2.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KIK49372.1 - 9.1e-44 148.5 0.3 1.3e-43 148.0 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 KIK49372.1 - 5.3e-06 25.8 3.1 0.0098 15.0 2.2 3.1 3 0 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KIK49372.1 - 1.1e-05 24.8 1.1 0.0017 17.7 0.5 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK49372.1 - 5e-05 22.7 0.2 0.032 13.5 0.0 2.5 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 KIK49372.1 - 0.0026 17.1 0.1 0.0049 16.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIK49372.1 - 0.0047 16.6 0.4 0.016 14.8 0.4 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIK49372.1 - 0.06 12.4 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 KIK49372.1 - 0.085 11.5 1.3 0.43 9.2 0.6 2.4 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.6 KIK49372.1 - 2.2 7.5 3.6 2.8 7.1 1.3 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase G-patch PF01585.23 KIK49373.1 - 6.7e-08 32.3 1.3 2e-07 30.8 1.3 1.9 1 0 0 1 1 1 1 G-patch domain SHR3_chaperone PF08229.11 KIK49374.1 - 8.3e-41 139.0 0.0 1e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 DUF4094 PF13334.6 KIK49374.1 - 0.13 12.7 0.1 0.67 10.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF2207 PF09972.9 KIK49374.1 - 1.2 7.8 4.6 3.2 6.4 4.7 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) LETM1 PF07766.13 KIK49375.1 - 2.1e-104 348.6 0.2 2.1e-104 348.6 0.2 1.9 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 KIK49375.1 - 0.00056 19.6 0.2 0.0052 16.5 0.0 2.8 3 0 0 3 3 3 1 SAP domain EF-hand_7 PF13499.6 KIK49375.1 - 0.028 14.8 0.6 0.52 10.8 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.32 KIK49375.1 - 0.029 13.9 0.5 0.13 11.9 0.0 2.4 2 0 0 2 2 2 0 EF hand 2OG-FeII_Oxy_2 PF13532.6 KIK49376.1 - 1.6e-30 106.8 0.0 3.4e-28 99.2 0.0 2.2 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily TF_Zn_Ribbon PF08271.12 KIK49377.1 - 0.0023 17.4 2.2 0.0053 16.3 2.2 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Spore_coat_CotO PF14153.6 KIK49377.1 - 0.12 12.3 0.3 0.22 11.4 0.3 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Prok-RING_1 PF14446.6 KIK49377.1 - 0.64 10.0 3.1 1.4 8.9 3.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-trcl PF13451.6 KIK49377.1 - 2.5 8.1 4.2 6.5 6.7 0.2 2.5 2 0 0 2 2 2 0 Probable zinc-ribbon domain Glycos_transf_1 PF00534.20 KIK49378.1 - 6.1e-20 71.5 0.0 1.3e-19 70.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIK49378.1 - 1.3e-12 48.3 0.0 2.3e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KIK49378.1 - 3.2e-07 30.7 0.0 6.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIK49378.1 - 0.051 13.6 0.3 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Glyco_transf_20 PF00982.21 KIK49378.1 - 0.22 10.2 0.0 2.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 20 Glyco_hydro_20 PF00728.22 KIK49380.1 - 1.9e-88 297.3 0.0 2.3e-88 297.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KIK49380.1 - 6.3e-11 43.1 0.1 2.2e-10 41.3 0.1 1.9 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KIK49380.1 - 3.3e-05 24.7 0.1 9.8e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 F-box-like PF12937.7 KIK49382.1 - 0.00018 21.4 0.5 0.0012 18.7 0.0 2.7 3 0 0 3 3 3 1 F-box-like MFS_1 PF07690.16 KIK49384.1 - 5.4e-37 127.5 32.9 5.4e-37 127.5 32.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIK49384.1 - 6.8e-08 31.8 11.4 6.8e-08 31.8 11.4 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter p450 PF00067.22 KIK49386.1 - 6.6e-74 249.3 0.0 8e-74 249.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DNA_pol_phi PF04931.13 KIK49387.1 - 3.5e-203 676.9 10.4 3.5e-203 676.9 10.4 2.1 3 0 0 3 3 3 1 DNA polymerase phi MutS_V PF00488.21 KIK49388.1 - 1e-67 227.8 0.1 2.2e-67 226.7 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KIK49388.1 - 1.8e-34 119.7 1.7 4.5e-34 118.3 0.8 2.1 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 KIK49388.1 - 5.3e-21 75.0 0.3 1.2e-20 73.9 0.3 1.6 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 KIK49388.1 - 3e-09 37.1 0.1 8e-09 35.7 0.1 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KIK49388.1 - 8.6e-09 35.8 0.1 4.2e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 MutS domain II ATP12 PF07542.11 KIK49389.1 - 1.7e-41 141.3 0.1 2.9e-41 140.5 0.1 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein Nt_Gln_amidase PF09764.9 KIK49390.1 - 5.6e-59 198.8 0.1 6.7e-59 198.6 0.1 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase BTB PF00651.31 KIK49391.1 - 0.00088 19.5 0.0 0.0014 18.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF1054 PF06335.12 KIK49393.1 - 0.012 15.6 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) UQ_con PF00179.26 KIK49394.1 - 3.1e-39 133.8 0.1 3.5e-39 133.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KIK49394.1 - 0.069 13.0 0.2 0.13 12.2 0.2 1.4 1 1 0 1 1 1 0 UEV domain Leader_Trp PF08255.11 KIK49395.1 - 8.7 6.6 8.8 0.18 11.8 1.2 2.3 2 0 0 2 2 2 0 Trp-operon Leader Peptide DDE_Tnp_4 PF13359.6 KIK49396.1 - 0.0018 18.0 0.2 0.0025 17.5 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KIK49396.1 - 0.0061 16.2 0.0 0.0073 15.9 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 KIK49397.1 - 3.5e-09 36.5 0.0 3.7e-09 36.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KIK49397.1 - 0.0023 17.6 0.0 0.0025 17.5 0.0 1.0 1 0 0 1 1 1 1 Transposase DDE domain zinc_ribbon_9 PF14369.6 KIK49398.1 - 0.45 10.8 2.9 9.7 6.6 2.9 2.3 1 1 0 1 1 1 0 zinc-ribbon SPRY PF00622.28 KIK49399.1 - 1.4e-08 34.8 0.0 1.7e-06 28.2 0.0 2.8 3 0 0 3 3 3 1 SPRY domain DUF664 PF04978.12 KIK49399.1 - 0.59 10.5 3.3 0.81 10.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF664) DUF2956 PF11169.8 KIK49399.1 - 1.9 8.7 7.4 0.17 12.1 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) CAP_C PF08603.11 KIK49402.1 - 7.3e-59 197.9 8.2 8.5e-59 197.7 8.2 1.0 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KIK49402.1 - 0.011 15.5 8.3 0.037 13.8 2.7 2.1 1 1 0 2 2 2 0 Tubulin binding cofactor C AIM3 PF17096.5 KIK49403.1 - 2.7 9.0 6.1 4.4 8.3 6.0 1.6 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 3 eIF3m_C_helix PF18005.1 KIK49404.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix Retrotran_gag_2 PF14223.6 KIK49405.1 - 2.2e-06 27.4 0.0 3.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Adenyl_transf PF04439.12 KIK49405.1 - 0.00064 18.9 0.0 0.00087 18.5 0.0 1.2 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Retrotran_gag_3 PF14244.6 KIK49405.1 - 0.014 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type ZapB PF06005.12 KIK49406.1 - 0.0079 16.6 3.9 0.59 10.6 0.4 2.5 2 0 0 2 2 2 2 Cell division protein ZapB EpsG PF14897.6 KIK49406.1 - 0.11 11.8 11.3 0.16 11.2 11.3 1.2 1 0 0 1 1 1 0 EpsG family APG6_N PF17675.1 KIK49406.1 - 0.26 11.8 12.9 1.7 9.2 6.6 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF5398 PF17376.2 KIK49406.1 - 2.1 9.0 6.5 4.8 7.9 6.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5398) Ribosomal_S12 PF17487.2 KIK49406.1 - 4.2 8.2 8.0 6.9 7.5 8.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S12 Myb_DNA-bind_7 PF15963.5 KIK49408.1 - 4e-20 71.5 0.1 7.5e-20 70.6 0.1 1.4 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KIK49408.1 - 3.5e-08 33.5 0.0 6.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain OspE PF02471.17 KIK49408.1 - 0.0054 16.9 0.0 0.0098 16.1 0.0 1.3 1 0 0 1 1 1 1 Borrelia outer surface protein E Myb_DNA-bind_6 PF13921.6 KIK49408.1 - 0.016 15.4 0.1 0.033 14.4 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain RNA_pol_Rpb2_6 PF00562.28 KIK49409.1 - 6e-127 423.9 0.2 8.5e-127 423.4 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KIK49409.1 - 2.4e-68 229.7 0.0 3.5e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KIK49409.1 - 6.5e-49 166.2 0.6 7.8e-48 162.6 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KIK49409.1 - 2.2e-32 111.3 0.1 5.6e-32 110.0 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 KIK49409.1 - 2.7e-26 91.6 0.4 8.5e-26 90.0 0.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KIK49409.1 - 7.6e-26 90.1 0.1 2e-25 88.7 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KIK49409.1 - 1.6e-23 83.0 0.4 4.7e-23 81.5 0.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 KIK49409.1 - 1.9 9.2 4.2 0.65 10.7 0.8 1.9 2 0 0 2 2 2 0 MRN-interacting protein HORMA PF02301.18 KIK49410.1 - 4.8e-09 36.1 0.2 5.4e-09 35.9 0.2 1.3 1 1 0 1 1 1 1 HORMA domain PX PF00787.24 KIK49411.1 - 2.3e-19 69.4 0.6 1e-18 67.3 0.5 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 KIK49411.1 - 1.5e-07 31.3 4.4 0.0071 15.9 4.3 2.4 1 1 0 2 2 2 2 Vps5 C terminal like Lung_7-TM_R PF06814.13 KIK49412.1 - 1.6e-60 204.9 18.9 2.1e-60 204.5 18.9 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor UBA2_C PF16195.5 KIK49412.1 - 2.5 8.9 7.1 4.5 8.0 7.1 1.4 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Glyco_transf_8 PF01501.20 KIK49413.1 - 2.1e-24 86.5 0.0 7.5e-24 84.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KIK49413.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative HisKA_3 PF07730.13 KIK49414.1 - 0.061 13.9 9.9 3.6 8.2 0.4 3.5 4 0 0 4 4 4 0 Histidine kinase DUF883 PF05957.13 KIK49414.1 - 0.4 11.3 16.4 0.46 11.1 0.4 3.5 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Tape_meas_lam_C PF09718.10 KIK49414.1 - 0.54 10.4 8.6 0.17 12.1 1.3 3.0 2 1 1 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Lactococcin_972 PF09683.10 KIK49414.1 - 7.1 7.3 9.0 0.39 11.3 1.1 2.7 2 0 0 2 2 2 0 Bacteriocin (Lactococcin_972) Homeodomain PF00046.29 KIK49416.1 - 8.9e-12 44.7 1.0 2.1e-11 43.5 1.0 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KIK49416.1 - 4.5e-08 32.9 1.4 1.6e-07 31.1 0.2 2.4 3 0 0 3 3 3 1 Homeobox KN domain Homez PF11569.8 KIK49416.1 - 0.0065 15.9 0.0 0.0065 15.9 0.0 2.0 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez Mating_C PF12737.7 KIK49417.1 - 6.7e-24 84.9 24.5 6.8e-23 81.6 24.5 2.2 1 1 0 1 1 1 1 C-terminal domain of homeodomain 1 Homeobox_KN PF05920.11 KIK49417.1 - 6.4e-11 42.0 0.6 2e-10 40.4 0.1 2.2 2 0 0 2 2 2 1 Homeobox KN domain Mating_N PF12731.7 KIK49417.1 - 3.4e-05 23.8 0.7 8.8e-05 22.5 0.7 1.8 1 0 0 1 1 1 1 Mating-type protein beta 1 Acetyltransf_2 PF00797.17 KIK49417.1 - 0.14 12.0 0.2 0.22 11.3 0.2 1.2 1 0 0 1 1 1 0 N-acetyltransferase DUF2252 PF10009.9 KIK49417.1 - 0.21 10.6 3.4 0.31 10.1 3.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Peptidase_M3 PF01432.20 KIK49418.1 - 1.4e-126 423.5 0.0 1.8e-126 423.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 WSD PF15613.6 KIK49420.1 - 0.002 18.5 0.3 0.0083 16.6 0.3 2.2 1 1 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif APG6_N PF17675.1 KIK49420.1 - 0.86 10.1 6.3 1.7 9.1 6.3 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1754 PF08555.10 KIK49421.1 - 8.3e-14 52.2 3.4 8.3e-14 52.2 3.4 1.4 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) DUF4191 PF13829.6 KIK49421.1 - 0.016 14.6 0.3 0.026 13.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) BING4CT PF08149.11 KIK49421.1 - 0.035 13.9 0.9 0.34 10.7 0.0 2.0 1 1 1 2 2 2 0 BING4CT (NUC141) domain DUF1751 PF08551.10 KIK49422.1 - 6.5e-21 74.8 4.8 1.1e-20 74.0 4.8 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KIK49422.1 - 0.037 14.0 6.8 0.086 12.8 6.8 1.6 1 1 0 1 1 1 0 Rhomboid family Vps51 PF08700.11 KIK49423.1 - 6.1e-14 51.9 0.4 2.1e-13 50.2 0.4 2.0 1 0 0 1 1 1 1 Vps51/Vps67 DRY_EERY PF09750.9 KIK49423.1 - 0.011 16.0 1.3 0.022 15.0 1.3 1.4 1 0 0 1 1 1 0 Alternative splicing regulator COG2 PF06148.11 KIK49423.1 - 0.088 12.9 0.3 0.31 11.1 0.3 1.9 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 CARD PF00619.21 KIK49423.1 - 0.093 12.8 0.0 0.31 11.1 0.0 1.9 1 0 0 1 1 1 0 Caspase recruitment domain SecE PF00584.20 KIK49425.1 - 3.8e-15 55.5 0.0 4.4e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex PPR_2 PF13041.6 KIK49426.1 - 1.1e-24 86.4 0.0 0.0011 19.1 0.0 8.2 7 1 1 8 8 8 6 PPR repeat family PPR_3 PF13812.6 KIK49426.1 - 3.4e-15 55.8 0.0 0.095 12.8 0.0 7.5 6 3 3 9 9 9 5 Pentatricopeptide repeat domain PPR PF01535.20 KIK49426.1 - 2.3e-14 52.6 5.8 0.01 16.0 0.0 8.2 10 0 0 10 10 10 4 PPR repeat PPR_long PF17177.4 KIK49426.1 - 8.5e-11 41.6 0.0 0.077 12.4 0.0 4.5 4 1 0 4 4 4 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KIK49426.1 - 7.2e-06 25.6 10.7 0.00055 19.6 0.0 4.7 7 0 0 7 7 7 2 PPR repeat Cdc6_C PF09079.11 KIK49426.1 - 0.029 14.3 0.0 2.3 8.2 0.0 3.4 4 0 0 4 4 4 0 CDC6, C terminal winged helix domain GDC-P PF02347.16 KIK49427.1 - 1.6e-183 610.4 0.0 8.6e-177 588.3 0.0 2.6 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 KIK49427.1 - 0.00094 18.2 0.8 0.064 12.2 0.1 2.4 2 1 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 KIK49427.1 - 0.0025 17.2 0.1 0.0099 15.2 0.0 1.9 2 0 0 2 2 2 1 Beta-eliminating lyase DUF1741 PF08427.10 KIK49428.1 - 2.2e-28 99.5 0.0 3.6e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) ubiquitin PF00240.23 KIK49430.1 - 8.5e-07 28.6 0.4 4.7e-06 26.3 0.4 1.8 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KIK49430.1 - 6.7e-06 26.5 0.2 2.8e-05 24.5 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain RAWUL PF16207.5 KIK49430.1 - 0.016 15.8 0.0 0.019 15.6 0.0 1.1 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like PI3K_rbd PF00794.18 KIK49430.1 - 0.021 15.0 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain Rad60-SLD PF11976.8 KIK49430.1 - 0.04 13.8 0.2 0.24 11.2 0.2 1.9 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Arrestin_C PF02752.22 KIK49431.1 - 2.3e-09 37.8 0.0 6.6e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 KIK49431.1 - 0.083 12.6 0.0 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 Arrestin_N terminal like Vta1 PF04652.16 KIK49432.1 - 7.6e-47 158.9 0.5 1.2e-46 158.3 0.5 1.3 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 KIK49432.1 - 9.1e-15 54.1 0.2 9.1e-15 54.1 0.2 2.1 3 0 0 3 3 3 1 Vta1 C-terminal domain Nucleo_P87 PF07267.11 KIK49433.1 - 0.16 10.8 0.6 0.2 10.4 0.6 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PBP1_TM PF14812.6 KIK49433.1 - 3.3 8.2 8.1 7.8 7.0 8.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MMR_HSR1 PF01926.23 KIK49435.1 - 2.1e-14 53.6 0.0 1.5e-13 50.8 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIK49435.1 - 1.2e-07 31.4 0.0 1.1e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KIK49435.1 - 1e-05 25.5 0.0 0.0066 16.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KIK49435.1 - 0.012 15.7 0.7 0.094 12.8 0.1 2.4 1 1 1 2 2 2 0 Dynamin family Roc PF08477.13 KIK49435.1 - 0.16 12.2 0.0 2 8.7 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Pyr_redox_2 PF07992.14 KIK49436.1 - 1.9e-36 125.8 0.7 2.4e-36 125.5 0.7 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK49436.1 - 1.3e-16 60.9 1.1 1.2e-12 48.2 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK49436.1 - 3e-10 39.9 0.0 4.7e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIK49436.1 - 6.6e-05 22.1 3.3 0.057 12.5 0.3 3.4 3 1 1 4 4 4 2 Lycopene cyclase protein K_oxygenase PF13434.6 KIK49436.1 - 0.00052 19.3 0.3 0.061 12.4 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KIK49436.1 - 0.0007 18.4 2.0 8.8 4.9 0.0 4.4 4 1 1 5 5 5 1 HI0933-like protein NAD_binding_9 PF13454.6 KIK49436.1 - 0.00099 19.1 2.4 0.6 10.1 0.0 3.7 4 0 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 KIK49436.1 - 0.0012 18.5 11.7 0.26 10.8 0.0 3.9 3 1 1 4 4 4 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIK49436.1 - 0.0017 17.3 2.6 0.0058 15.5 0.0 2.3 2 1 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.17 KIK49436.1 - 0.0038 16.5 0.1 0.3 10.3 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 KIK49436.1 - 0.0085 16.5 0.2 0.44 11.0 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KIK49436.1 - 0.017 14.2 6.3 0.37 9.8 0.0 3.2 2 1 1 3 3 3 0 FAD binding domain TrkA_N PF02254.18 KIK49436.1 - 0.026 14.8 1.0 6.8 7.0 0.3 2.6 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_8 PF13450.6 KIK49436.1 - 0.026 14.8 0.8 0.58 10.4 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KIK49436.1 - 0.028 13.7 1.6 0.39 9.9 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Cpn60_TCP1 PF00118.24 KIK49436.1 - 0.2 10.2 0.1 0.89 8.1 0.0 1.8 2 0 0 2 2 2 0 TCP-1/cpn60 chaperonin family Shikimate_DH PF01488.20 KIK49436.1 - 0.29 11.2 0.9 5.4 7.1 0.0 2.7 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KIK49436.1 - 0.67 9.0 6.3 13 4.7 0.0 3.7 4 1 1 5 5 5 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KIK49436.1 - 0.78 9.0 6.4 2.6 7.3 0.1 2.6 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 KIK49437.1 - 7.8e-14 52.2 0.0 1.6e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIK49437.1 - 1.2e-10 41.8 0.0 2.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIK49437.1 - 2.9e-09 37.0 0.0 6.1e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIK49437.1 - 9.2e-07 28.4 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIK49437.1 - 3.9e-06 26.7 0.0 8.3e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KIK49437.1 - 5.6e-06 25.8 0.0 8.9e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KIK49437.1 - 6.4e-06 26.8 0.0 1.2e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KIK49437.1 - 0.0017 17.8 0.1 0.013 14.9 0.0 2.3 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_29 PF03141.16 KIK49437.1 - 0.013 14.1 0.0 0.019 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase WD40 PF00400.32 KIK49438.1 - 3.1e-15 56.3 15.9 0.0067 17.2 0.1 8.1 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK49438.1 - 0.00016 21.9 0.6 0.077 13.3 0.0 4.5 4 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Homeodomain PF00046.29 KIK49439.1 - 2.9e-14 52.7 2.6 7.8e-14 51.3 2.6 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KIK49439.1 - 0.00021 21.1 0.0 0.00046 20.0 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain F-box-like PF12937.7 KIK49440.1 - 2.8e-05 23.9 0.9 6.1e-05 22.8 0.9 1.6 1 0 0 1 1 1 1 F-box-like DUF3437 PF11919.8 KIK49440.1 - 0.14 12.1 1.2 0.43 10.5 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) PB1 PF00564.24 KIK49442.1 - 1.5e-11 44.1 0.0 3.4e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 PB1 domain CENP-H PF05837.12 KIK49442.1 - 0.43 11.0 2.5 5 7.6 0.4 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Aldo_ket_red PF00248.21 KIK49443.1 - 9.1e-37 126.8 0.0 1.2e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ApbA_C PF08546.11 KIK49444.1 - 1.1e-34 119.3 0.1 1.8e-34 118.6 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KIK49444.1 - 1.2e-22 80.2 0.0 1.1e-21 77.1 0.0 2.1 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA O-FucT PF10250.9 KIK49445.1 - 7.7e-10 39.0 0.0 1.9e-09 37.7 0.0 1.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase TPT PF03151.16 KIK49446.1 - 2.3e-11 43.6 17.9 3.1e-11 43.2 17.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KIK49446.1 - 2.1e-06 27.9 32.1 4.2e-06 27.0 13.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 KIK49446.1 - 0.0071 15.3 0.7 0.0071 15.3 0.7 2.6 2 1 1 3 3 3 1 CRT-like, chloroquine-resistance transporter-like DUF5381 PF17353.2 KIK49446.1 - 0.018 14.8 1.4 0.018 14.8 1.4 2.6 3 1 1 4 4 4 0 Family of unknown function (DUF5381) YccV-like PF08755.11 KIK49448.1 - 7e-25 87.4 0.0 1.6e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 KIK49448.1 - 3e-10 39.9 0.1 7.3e-10 38.6 0.0 1.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily F-box-like PF12937.7 KIK49448.1 - 0.013 15.4 0.7 0.19 11.7 0.1 2.6 2 0 0 2 2 2 0 F-box-like Acetyltransf_10 PF13673.7 KIK49449.1 - 2.1e-07 30.9 0.0 3.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIK49449.1 - 2.3e-06 27.5 0.0 4.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 KIK49449.1 - 5.5e-06 26.6 0.0 9.5e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIK49449.1 - 7.7e-06 26.3 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIK49449.1 - 0.0024 17.9 0.0 0.0049 17.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 KIK49449.1 - 0.019 14.5 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Amidase PF01425.21 KIK49451.1 - 7.3e-105 351.5 0.0 9.8e-105 351.1 0.0 1.2 1 0 0 1 1 1 1 Amidase dCMP_cyt_deam_1 PF00383.23 KIK49453.1 - 4.3e-06 26.5 0.0 6.3e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region HEAT PF02985.22 KIK49454.1 - 0.0018 18.4 0.3 0.11 12.8 0.0 3.5 2 0 0 2 2 2 1 HEAT repeat DUF1262 PF06880.11 KIK49454.1 - 0.026 14.9 0.0 0.052 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1262) Chorismate_bind PF00425.18 KIK49455.1 - 8.6e-62 209.0 0.0 3.1e-61 207.2 0.0 1.9 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 KIK49455.1 - 3.9e-34 118.1 0.0 5.6e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KIK49455.1 - 5.9e-13 49.2 0.0 4.6e-12 46.4 0.0 2.4 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KIK49455.1 - 0.0011 18.8 0.3 0.0063 16.3 0.3 2.0 1 1 0 1 1 1 1 Peptidase C26 DIOX_N PF14226.6 KIK49456.1 - 2.3e-05 25.1 0.1 7.8e-05 23.4 0.1 2.0 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK49456.1 - 0.00065 20.1 0.0 0.0012 19.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UQ_con PF00179.26 KIK49457.1 - 8.6e-40 135.6 0.1 1.1e-39 135.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KIK49457.1 - 0.026 14.4 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain Transthyretin PF00576.21 KIK49458.1 - 2.3e-37 128.0 0.0 2.6e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family Nop52 PF05997.12 KIK49459.1 - 6.2e-73 245.2 0.0 8.4e-73 244.7 0.0 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMS19_N PF14500.6 KIK49459.1 - 0.00011 21.8 0.0 0.00029 20.5 0.0 1.7 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II DDT PF02791.17 KIK49459.1 - 0.09 13.1 0.1 0.23 11.8 0.1 1.6 1 0 0 1 1 1 0 DDT domain TAN PF11640.8 KIK49459.1 - 0.097 12.8 0.0 0.81 9.8 0.0 2.4 2 1 0 2 2 2 0 Telomere-length maintenance and DNA damage repair RabGAP-TBC PF00566.18 KIK49460.1 - 2.3e-10 40.5 0.0 5.7e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pet100 PF09803.9 KIK49460.1 - 0.01 16.3 0.6 0.026 15.0 0.6 1.6 1 0 0 1 1 1 0 Pet100 SBE2 PF17076.5 KIK49460.1 - 5.1 5.2 7.2 0.1 10.8 0.4 1.5 2 0 0 2 2 2 0 SBE2, cell-wall formation GCP_C_terminal PF04130.13 KIK49461.1 - 1.9e-31 109.7 0.0 2.9e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KIK49461.1 - 1.2e-24 87.5 0.1 9.7e-23 81.2 0.1 2.5 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal Pyrophosphatase PF00719.19 KIK49462.1 - 2e-59 200.0 0.1 2.6e-59 199.6 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase I-set PF07679.16 KIK49463.1 - 0.096 12.8 0.0 2.6 8.2 0.0 3.3 4 0 0 4 4 4 0 Immunoglobulin I-set domain dsrm PF00035.26 KIK49464.1 - 2.2e-11 44.3 0.1 2.2e-11 44.3 0.1 2.4 3 0 0 3 3 3 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 KIK49464.1 - 1.1e-05 25.6 0.0 2.5e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KIK49464.1 - 0.0025 18.4 0.0 0.017 15.8 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 KIK49465.1 - 9.8e-09 35.8 0.0 1.9e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 KIK49465.1 - 7.9e-06 26.1 0.0 1.1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like CENP-T_C PF15511.6 KIK49467.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIK49467.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIK49467.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIK49467.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIK49467.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIK49467.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Glyco_transf_22 PF03901.17 KIK49469.1 - 1.1e-81 275.3 15.7 1.5e-81 274.8 15.7 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family FtsX PF02687.21 KIK49470.1 - 0.7 10.4 5.7 0.54 10.8 0.1 2.6 1 1 1 2 2 2 0 FtsX-like permease family F-box PF00646.33 KIK49471.1 - 1.5e-05 24.7 0.9 1.5e-05 24.7 0.9 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIK49471.1 - 0.00024 20.9 1.0 0.00024 20.9 1.0 1.7 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KIK49471.1 - 0.065 13.1 0.3 0.14 12.0 0.3 1.5 1 0 0 1 1 1 0 F-box PRANC PF09372.10 KIK49471.1 - 0.21 12.0 0.1 0.4 11.0 0.1 1.5 1 0 0 1 1 1 0 PRANC domain His_Phos_2 PF00328.22 KIK49472.1 - 1.1e-46 160.0 0.0 1.3e-46 159.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) CutC PF03932.14 KIK49473.1 - 3.2e-60 203.1 0.1 3.8e-60 202.8 0.1 1.0 1 0 0 1 1 1 1 CutC family DUF5449 PF17528.2 KIK49473.1 - 0.084 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5449) Bromodomain PF00439.25 KIK49475.1 - 3.6e-37 126.3 5.4 2.3e-18 66.1 0.3 2.4 2 0 0 2 2 2 2 Bromodomain YL1 PF05764.13 KIK49475.1 - 0.24 11.5 12.7 0.035 14.2 4.4 2.2 2 0 0 2 2 2 0 YL1 nuclear protein AT_hook PF02178.19 KIK49475.1 - 4.3 7.5 18.0 0.9 9.6 8.1 2.9 2 0 0 2 2 2 0 AT hook motif DUF4611 PF15387.6 KIK49475.1 - 7 7.0 13.1 24 5.2 0.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) TFIIF_alpha PF05793.12 KIK49475.1 - 7.3 5.0 18.3 0.3 9.6 6.6 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP1_TM PF14812.6 KIK49475.1 - 8.4 6.8 16.4 0.07 13.5 3.0 2.9 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DHHC PF01529.20 KIK49477.1 - 1.2e-34 119.3 8.5 1.2e-34 119.3 8.5 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.6 KIK49477.1 - 0.24 11.3 0.8 0.45 10.4 0.8 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily SAS4 PF15460.6 KIK49479.1 - 1.2e-05 25.3 2.2 2.5e-05 24.3 2.2 1.5 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 PEHE PF15275.6 KIK49479.1 - 0.00012 22.7 0.1 0.00012 22.7 0.1 2.9 2 1 0 2 2 2 1 PEHE domain ACT_7 PF13840.6 KIK49480.1 - 2.4e-18 65.7 0.0 7.6e-18 64.1 0.0 1.7 2 0 0 2 2 2 1 ACT domain Ribonuclease_T2 PF00445.18 KIK49481.1 - 9e-38 130.3 0.4 1.2e-37 129.9 0.4 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Gar1 PF04410.14 KIK49482.1 - 1.4e-32 112.7 0.6 1.4e-32 112.7 0.6 1.7 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region DUF5320 PF17253.2 KIK49482.1 - 0.0062 17.6 5.1 0.0062 17.6 5.1 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5320) Gag_p6 PF08705.11 KIK49482.1 - 0.2 11.9 1.6 0.74 10.1 1.6 2.0 1 0 0 1 1 1 0 Gag protein p6 EF_TS PF00889.19 KIK49483.1 - 1.4e-16 60.7 0.0 1.5e-15 57.4 0.0 2.3 2 1 1 3 3 3 1 Elongation factor TS UBA PF00627.31 KIK49483.1 - 0.002 18.0 0.1 0.0046 16.8 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 KIK49483.1 - 0.036 13.9 0.2 0.08 12.8 0.2 1.6 1 0 0 1 1 1 0 UBA-like domain Med11 PF10280.9 KIK49483.1 - 0.037 14.5 0.0 1.7 9.1 0.0 2.3 2 0 0 2 2 2 0 Mediator complex protein Peptidase_M16 PF00675.20 KIK49484.1 - 3.4e-39 134.2 0.0 6.1e-39 133.4 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KIK49484.1 - 1.7e-35 122.7 0.0 3.1e-35 121.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Cellulase PF00150.18 KIK49485.1 - 1.2e-12 47.9 0.9 1.2e-12 47.9 0.9 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF4985 PF16373.5 KIK49485.1 - 0.06 13.8 0.1 0.24 11.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function Cellulase PF00150.18 KIK49486.1 - 7e-13 48.6 0.3 7e-13 48.6 0.3 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Phage_Orf51 PF06194.11 KIK49486.1 - 0.2 11.7 1.0 2.5 8.2 0.6 2.5 2 0 0 2 2 2 0 Phage Conserved Open Reading Frame 51 UDPGP PF01704.18 KIK49487.1 - 1.6e-51 175.3 0.0 2e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KIK49487.1 - 0.015 15.6 0.1 0.033 14.6 0.1 1.8 1 1 0 1 1 1 0 MobA-like NTP transferase domain Taxilin PF09728.9 KIK49488.1 - 2.1e-18 66.6 30.6 6.9e-10 38.6 20.1 2.4 2 0 0 2 2 2 2 Myosin-like coiled-coil protein Rad60-SLD PF11976.8 KIK49488.1 - 9.6e-08 31.8 0.8 0.0035 17.1 0.0 2.9 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like PriA_C PF18074.1 KIK49488.1 - 0.015 16.1 0.6 0.073 13.9 0.1 2.5 2 1 0 2 2 2 0 Primosomal protein N C-terminal domain ubiquitin PF00240.23 KIK49488.1 - 0.11 12.2 1.0 1.7 8.5 0.0 3.0 3 0 0 3 3 3 0 Ubiquitin family DUF2935 PF11155.8 KIK49488.1 - 0.23 11.8 5.9 0.055 13.8 2.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) TMEM237 PF15383.6 KIK49488.1 - 0.28 10.3 1.4 0.61 9.1 1.4 1.5 1 0 0 1 1 1 0 Transmembrane protein 237 BRCA-2_OB1 PF09103.10 KIK49489.1 - 2.9e-35 120.9 0.0 2.6e-34 117.8 0.0 2.2 2 0 0 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 KIK49489.1 - 3.2e-05 23.7 0.3 9.6e-05 22.1 0.3 1.8 1 1 0 1 1 1 1 BRCA2, helical AbiH PF14253.6 KIK49489.1 - 0.26 11.1 0.0 0.44 10.4 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH betaPIX_CC PF16523.5 KIK49492.1 - 0.015 15.1 0.2 0.015 15.1 0.2 1.7 2 0 0 2 2 2 0 betaPIX coiled coil Mito_carr PF00153.27 KIK49493.1 - 1.3e-51 172.4 0.4 8.9e-21 73.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PXA PF02194.15 KIK49494.1 - 2.6e-48 164.4 2.0 2e-47 161.5 0.9 2.9 3 1 0 3 3 3 1 PXA domain Nexin_C PF08628.12 KIK49494.1 - 5.5e-28 97.8 0.1 5.5e-28 97.8 0.1 3.0 4 0 0 4 4 4 1 Sorting nexin C terminal PX PF00787.24 KIK49494.1 - 1e-18 67.4 0.0 3.8e-18 65.5 0.0 2.0 1 0 0 1 1 1 1 PX domain RGS PF00615.19 KIK49494.1 - 5.9e-09 36.2 0.0 1.7e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_C54 PF03416.19 KIK49494.1 - 0.055 12.9 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C54 ABC_tran_CTD PF16326.5 KIK49494.1 - 0.4 11.0 3.8 0.4 11.0 1.4 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain Isy1 PF06246.12 KIK49494.1 - 0.53 9.8 3.1 0.36 10.4 0.1 2.1 2 1 1 3 3 3 0 Isy1-like splicing family Gcd10p PF04189.13 KIK49495.1 - 7.4e-65 219.0 0.0 1.9e-64 217.6 0.0 1.7 1 1 0 1 1 1 1 Gcd10p family UNC45-central PF11701.8 KIK49496.1 - 3.3e-29 101.8 0.4 7.3e-28 97.5 0.0 2.8 2 1 1 3 3 3 1 Myosin-binding striated muscle assembly central Arm PF00514.23 KIK49496.1 - 0.0011 18.9 3.9 0.27 11.3 0.6 4.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Dpy19 PF10034.9 KIK49496.1 - 0.11 10.6 0.1 0.17 10.0 0.1 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Myosin_head PF00063.21 KIK49497.1 - 2.6e-239 796.0 0.7 3.1e-239 795.7 0.7 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KIK49497.1 - 8.6e-51 172.3 0.2 1.4e-50 171.5 0.2 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_2 PF07653.17 KIK49497.1 - 7.8e-11 41.5 0.1 2e-10 40.2 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KIK49497.1 - 5.2e-10 39.0 0.2 1.2e-09 37.9 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIK49497.1 - 6.9e-10 38.4 1.2 1.4e-09 37.4 1.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 KIK49497.1 - 1.3e-05 25.3 0.7 3.4e-05 24.0 0.7 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_16 PF13191.6 KIK49497.1 - 0.05 14.0 0.0 0.17 12.3 0.0 1.9 2 0 0 2 2 1 0 AAA ATPase domain AAA_22 PF13401.6 KIK49497.1 - 0.057 13.7 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KIK49497.1 - 0.08 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase SepF PF04472.12 KIK49497.1 - 0.13 12.5 0.1 0.59 10.4 0.0 2.1 2 0 0 2 2 1 0 Cell division protein SepF NACHT PF05729.12 KIK49497.1 - 0.14 12.1 0.0 0.38 10.6 0.0 1.8 1 0 0 1 1 1 0 NACHT domain Hpr_kinase_C PF07475.12 KIK49497.1 - 0.15 11.6 1.7 8.2 5.9 0.1 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Lum_binding PF00677.17 KIK49499.1 - 2.8e-43 145.8 0.0 8.6e-21 73.7 0.0 2.3 2 0 0 2 2 2 2 Lumazine binding domain ABC_membrane PF00664.23 KIK49502.1 - 3.9e-50 171.0 13.6 2e-30 106.4 4.2 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIK49502.1 - 3.2e-49 166.9 0.1 1.7e-28 99.8 0.1 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIK49502.1 - 3e-08 33.4 5.4 0.0016 17.9 0.1 4.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KIK49502.1 - 7.4e-05 22.7 0.1 0.036 14.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KIK49502.1 - 9.3e-05 22.9 0.8 0.81 10.1 0.4 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KIK49502.1 - 0.00012 21.7 1.3 0.068 12.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.9 KIK49502.1 - 0.00022 20.3 0.6 0.1 11.5 0.1 2.4 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 KIK49502.1 - 0.00022 20.4 3.0 0.14 11.2 0.0 2.6 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_23 PF13476.6 KIK49502.1 - 0.0005 20.6 0.0 0.026 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KIK49502.1 - 0.00073 19.7 2.5 0.016 15.3 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 KIK49502.1 - 0.00095 19.2 0.2 0.49 10.5 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 KIK49502.1 - 0.0011 18.5 0.1 0.45 10.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 KIK49502.1 - 0.0051 16.1 0.4 0.48 9.7 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 KIK49502.1 - 0.0079 16.5 0.2 2.7 8.3 0.1 2.9 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KIK49502.1 - 0.0093 16.0 0.2 4.6 7.3 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_30 PF13604.6 KIK49502.1 - 0.011 15.5 0.1 4.2 7.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KIK49502.1 - 0.034 13.5 0.2 4.6 6.5 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 KIK49502.1 - 0.059 12.9 0.7 7.6 6.0 0.0 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region DUF815 PF05673.13 KIK49502.1 - 0.064 12.4 0.0 11 5.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 KIK49502.1 - 0.15 11.7 0.2 3.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 KIK49502.1 - 0.22 12.1 0.2 19 5.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 KIK49502.1 - 0.24 10.6 3.0 2.8 7.1 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 KIK49502.1 - 0.35 10.9 1.9 9.5 6.2 0.1 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) zf-RING_2 PF13639.6 KIK49503.1 - 6.5e-11 42.4 5.3 6.5e-11 42.4 5.3 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KIK49503.1 - 1.1e-09 38.4 4.4 1.1e-09 38.4 4.4 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KIK49503.1 - 8.3e-08 31.9 8.0 8.3e-08 31.9 8.0 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 KIK49503.1 - 9.8e-07 28.9 3.2 7.7e-06 26.1 2.0 2.5 2 0 0 2 2 2 1 zinc-ribbon zf-C3HC4 PF00097.25 KIK49503.1 - 1.6e-06 27.9 4.5 1.6e-06 27.9 4.5 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIK49503.1 - 4.1e-06 26.7 2.8 4.1e-06 26.7 2.8 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIK49503.1 - 4.1e-06 26.7 5.2 4.1e-06 26.7 5.2 2.1 3 0 0 3 3 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KIK49503.1 - 5.4e-06 26.4 0.4 1.2e-05 25.2 0.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KIK49503.1 - 6.9e-06 25.7 4.7 2.6e-05 23.9 4.7 2.0 1 1 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KIK49503.1 - 0.00025 20.8 1.7 0.00025 20.8 1.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIK49503.1 - 0.0083 16.0 4.0 0.0083 16.0 4.0 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 KIK49503.1 - 0.077 13.2 3.8 0.39 10.9 3.8 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain DNA_RNApol_7kD PF03604.13 KIK49503.1 - 0.87 9.3 3.2 15 5.4 0.4 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit PHD PF00628.29 KIK49503.1 - 1.3 8.9 12.6 0.19 11.6 2.7 2.7 3 0 0 3 3 3 0 PHD-finger zf-C2HC5 PF06221.13 KIK49503.1 - 1.5 8.9 8.2 1.7 8.7 1.3 2.8 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type DZR PF12773.7 KIK49503.1 - 4.9 7.3 8.8 5.2 7.2 1.0 2.8 2 1 0 2 2 2 0 Double zinc ribbon DUF2256 PF10013.9 KIK49503.1 - 7.1 6.8 5.7 7.5 6.8 0.2 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_ribbon_17 PF17120.5 KIK49503.1 - 9.9 5.9 8.5 0.72 9.5 2.4 2.1 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type Asp PF00026.23 KIK49504.1 - 1.2e-49 169.5 8.9 3.2e-49 168.1 8.9 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIK49504.1 - 2.2e-09 37.8 3.9 2.8e-05 24.4 0.1 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIK49504.1 - 0.0037 17.9 6.9 0.012 16.3 0.8 3.0 3 1 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 KIK49504.1 - 0.033 14.7 1.2 0.44 11.2 0.2 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KIK49504.1 - 0.066 13.0 0.3 11 5.8 0.0 2.6 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal Adhesin_E PF16747.5 KIK49507.1 - 0.17 11.9 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Surface-adhesin protein E DUF89 PF01937.19 KIK49509.1 - 2.2e-106 355.8 0.1 2.8e-106 355.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DAO PF01266.24 KIK49515.1 - 2.7e-24 86.4 0.0 3.2e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase ZapB PF06005.12 KIK49516.1 - 0.033 14.6 0.0 0.059 13.8 0.0 1.3 1 0 0 1 1 1 0 Cell division protein ZapB ADIP PF11559.8 KIK49516.1 - 0.069 13.2 0.5 0.11 12.6 0.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding LPP PF04728.13 KIK49516.1 - 0.081 13.3 0.3 0.15 12.5 0.3 1.4 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Cnn_1N PF07989.11 KIK49516.1 - 0.11 12.7 0.1 0.17 12.1 0.1 1.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Csm1_N PF18504.1 KIK49516.1 - 0.13 12.6 0.3 0.24 11.8 0.3 1.3 1 0 0 1 1 1 0 Csm1 N-terminal domain SlyX PF04102.12 KIK49516.1 - 0.17 12.6 0.9 0.45 11.2 0.9 1.7 1 0 0 1 1 1 0 SlyX Alanine_zipper PF11839.8 KIK49516.1 - 0.26 11.7 3.5 0.41 11.0 3.5 1.3 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein APC_u13 PF16634.5 KIK49516.1 - 5 7.1 9.9 0.78 9.7 0.5 3.3 3 0 0 3 3 3 0 Unstructured region on APC between APC_crr and SAMP Lgl_C PF08596.10 KIK49517.1 - 9.7e-38 129.9 0.0 4.5e-37 127.7 0.0 2.0 2 1 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 KIK49517.1 - 0.00044 20.5 0.0 0.13 12.5 0.0 4.6 5 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK49517.1 - 0.0051 17.6 2.7 0.091 13.7 0.1 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat NAD_binding_10 PF13460.6 KIK49518.1 - 8.7e-05 22.5 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding DUF1490 PF07371.12 KIK49518.1 - 0.086 12.9 0.3 0.14 12.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1490) V-SNARE_C PF12352.8 KIK49520.1 - 2.6e-12 46.8 1.8 2.6e-12 46.8 1.8 2.4 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus Lebercilin PF15619.6 KIK49520.1 - 0.00093 18.9 3.3 0.19 11.4 0.3 2.4 2 1 0 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease Sec20 PF03908.13 KIK49520.1 - 0.0026 17.6 0.5 0.01 15.7 0.1 2.1 2 0 0 2 2 2 1 Sec20 Sec8_exocyst PF04048.14 KIK49520.1 - 0.021 14.7 2.2 5 7.0 0.1 2.9 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain FTA4 PF13093.6 KIK49520.1 - 0.07 13.0 5.2 0.18 11.7 3.8 1.8 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 FTCD_C PF04961.12 KIK49520.1 - 0.089 12.5 0.1 11 5.7 0.0 2.2 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase Med30 PF11315.8 KIK49520.1 - 0.14 12.3 0.7 1.2 9.3 0.0 2.1 1 1 1 2 2 2 0 Mediator complex subunit 30 DUF1664 PF07889.12 KIK49520.1 - 0.42 10.6 1.8 44 4.1 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TatD_DNase PF01026.21 KIK49521.1 - 2.3e-20 73.0 0.1 3.5e-20 72.5 0.1 1.3 1 0 0 1 1 1 1 TatD related DNase Met_10 PF02475.16 KIK49522.1 - 2.1e-67 226.7 0.0 4.1e-67 225.8 0.0 1.5 2 0 0 2 2 2 1 Met-10+ like-protein MethyltransfD12 PF02086.15 KIK49522.1 - 0.02 14.6 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Mito_carr PF00153.27 KIK49523.1 - 4.9e-63 209.1 1.3 2.5e-21 75.4 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KIK49523.1 - 1.4e-18 67.1 2.4 1.6e-07 31.6 0.0 5.2 2 2 3 5 5 5 4 EF-hand domain pair EF-hand_1 PF00036.32 KIK49523.1 - 1.9e-17 61.5 5.7 2.9e-05 23.3 0.1 6.4 6 0 0 6 6 6 2 EF hand EF-hand_6 PF13405.6 KIK49523.1 - 1.7e-16 58.6 3.9 1e-05 25.1 0.1 6.4 7 0 0 7 7 7 2 EF-hand domain EF-hand_5 PF13202.6 KIK49523.1 - 1.2e-10 40.4 4.3 0.0008 18.8 0.1 4.2 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KIK49523.1 - 6e-10 38.8 3.4 0.0038 17.0 0.0 5.2 5 1 0 5 5 5 2 EF-hand domain pair DUF953 PF06110.11 KIK49524.1 - 1.5e-17 63.3 0.1 1.8e-17 63.1 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) MoaC PF01967.21 KIK49525.1 - 8e-49 165.2 1.4 1.4e-48 164.4 1.4 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KIK49525.1 - 5.7e-38 129.7 0.0 9.6e-38 129.0 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KIK49525.1 - 1.1e-26 94.3 0.0 1.7e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KIK49525.1 - 2.4e-05 24.6 0.0 5.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KIK49525.1 - 0.023 14.8 0.0 0.068 13.3 0.0 1.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain C2 PF00168.30 KIK49526.1 - 1.9e-83 275.4 0.6 2.7e-17 62.9 0.0 5.4 5 0 0 5 5 5 5 C2 domain MTS PF05175.14 KIK49527.1 - 2.8e-09 36.7 0.0 6.1e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase small domain Kinesin PF00225.23 KIK49528.1 - 4.6e-80 269.0 0.0 2.2e-79 266.8 0.0 2.1 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KIK49528.1 - 3.4e-16 59.5 0.0 2.1e-11 43.9 0.0 3.4 3 0 0 3 3 3 3 Microtubule binding Spc7 PF08317.11 KIK49529.1 - 7.1e-91 304.3 18.3 9.8e-91 303.9 18.3 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 KIK49529.1 - 1.7e-10 40.8 0.0 3.3e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Spc7_C2 CENP-F_leu_zip PF10473.9 KIK49529.1 - 0.0016 18.5 18.9 0.0069 16.4 5.3 2.4 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MAD PF05557.13 KIK49529.1 - 0.089 11.2 20.0 0.14 10.5 20.0 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Snapin_Pallidin PF14712.6 KIK49529.1 - 0.19 12.2 4.5 0.51 10.8 4.5 1.7 1 0 0 1 1 1 0 Snapin/Pallidin Atg14 PF10186.9 KIK49529.1 - 0.37 9.8 5.9 0.8 8.7 5.9 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YojJ PF10372.9 KIK49529.1 - 0.64 10.2 2.5 0.49 10.5 0.5 1.9 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus TMPIT PF07851.13 KIK49529.1 - 1.9 7.6 7.3 3.2 6.9 7.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein FapA PF03961.13 KIK49529.1 - 2.5 6.6 7.9 4.7 5.7 7.9 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A Baculo_PEP_C PF04513.12 KIK49529.1 - 3.5 7.7 5.9 5 7.2 3.9 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ING PF12998.7 KIK49529.1 - 6.6 7.4 11.6 2.8 8.6 0.8 2.9 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding CC2-LZ PF16516.5 KIK49530.1 - 0.018 15.4 4.7 0.018 15.4 4.7 2.2 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DIE2_ALG10 PF04922.12 KIK49531.1 - 1.7e-122 409.5 5.3 1.7e-122 409.5 5.3 1.4 2 0 0 2 2 2 1 DIE2/ALG10 family TauD PF02668.16 KIK49532.1 - 5.9e-55 186.9 0.8 7.1e-55 186.7 0.8 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pkinase PF00069.25 KIK49533.1 - 2.4e-62 210.7 0.0 3e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK49533.1 - 2.2e-30 105.8 0.0 2.8e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIK49533.1 - 9.1e-05 21.9 0.1 0.0006 19.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KIK49533.1 - 0.00022 20.3 0.0 0.00059 18.9 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KIK49533.1 - 0.003 17.0 0.0 0.0058 16.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIK49533.1 - 0.007 16.3 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family OPT PF03169.15 KIK49534.1 - 5.2e-181 603.4 63.8 6e-181 603.2 63.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Bacillus_PapR PF05968.11 KIK49534.1 - 0.1 12.5 1.2 0.39 10.6 1.2 2.0 1 0 0 1 1 1 0 Bacillus PapR protein DUF2418 PF10332.9 KIK49534.1 - 0.26 11.8 0.1 0.26 11.8 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2418) Prp19 PF08606.11 KIK49535.1 - 9.1e-31 105.7 3.0 9.1e-31 105.7 3.0 1.8 2 0 0 2 2 2 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 KIK49535.1 - 8.7e-11 42.0 0.0 2.6e-05 24.5 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIK49535.1 - 3.9e-08 33.8 3.5 0.025 15.4 0.0 5.9 6 0 0 6 6 6 1 WD domain, G-beta repeat U-box PF04564.15 KIK49535.1 - 1.9e-05 24.7 0.0 4.6e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KIK49535.1 - 5.8e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KIK49535.1 - 0.0036 17.4 0.0 0.012 15.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein Nbas_N PF15492.6 KIK49535.1 - 0.022 14.1 0.0 0.1 11.9 0.0 1.9 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Rtf2 PF04641.12 KIK49535.1 - 0.069 12.5 0.1 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Rtf2 RING-finger Frtz PF11768.8 KIK49535.1 - 0.15 10.3 0.0 0.3 9.4 0.0 1.4 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Methyltransf_16 PF10294.9 KIK49537.1 - 2.7e-16 59.8 0.0 4.3e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 KIK49537.1 - 0.00054 20.7 0.0 0.0026 18.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIK49537.1 - 0.00072 20.2 0.0 0.0037 18.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain DUF3918 PF13056.6 KIK49537.1 - 0.1 12.2 0.2 0.25 11.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Myb_DNA-binding PF00249.31 KIK49539.1 - 1.2e-36 124.7 11.3 2.3e-14 53.3 0.5 3.8 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIK49539.1 - 2.4e-34 117.4 6.6 3.9e-15 55.8 0.1 3.6 1 1 2 3 3 3 3 Myb-like DNA-binding domain zf-C2H2_aberr PF17017.5 KIK49539.1 - 1.8e-07 31.5 0.9 0.0045 17.2 0.2 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger SANT_DAMP1_like PF16282.5 KIK49539.1 - 0.00011 22.3 0.8 0.5 10.6 0.1 2.5 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 KIK49539.1 - 0.016 15.2 0.0 2.6 8.1 0.0 2.7 2 1 1 3 3 3 0 SLIDE Rap1_C PF11626.8 KIK49539.1 - 0.15 12.2 0.7 19 5.4 0.0 3.0 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain zf-C2H2_4 PF13894.6 KIK49539.1 - 3.8 8.6 12.9 2.4 9.2 0.0 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger WD40 PF00400.32 KIK49540.1 - 1.6e-31 107.8 13.4 1.7e-07 31.8 0.2 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIK49540.1 - 7e-10 39.1 0.2 0.14 12.5 0.1 4.5 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KIK49540.1 - 0.0034 17.0 0.0 0.7 9.4 0.0 2.5 2 1 0 2 2 2 2 PQQ-like domain Cytochrom_D1 PF02239.16 KIK49540.1 - 0.021 13.3 0.0 1.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 KIK49540.1 - 0.095 12.7 0.6 5.8 7.0 0.2 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat MCM PF00493.23 KIK49541.1 - 7.7e-97 322.8 0.0 1.6e-96 321.8 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KIK49541.1 - 1.9e-35 121.4 0.0 3.6e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KIK49541.1 - 7.4e-22 77.6 1.3 1.4e-21 76.7 1.3 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KIK49541.1 - 1.8e-14 54.2 0.1 6.2e-14 52.5 0.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KIK49541.1 - 1.1e-07 31.5 0.1 2e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KIK49541.1 - 0.0042 16.9 0.0 0.016 15.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KIK49541.1 - 0.018 14.8 0.0 0.051 13.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain NST1 PF13945.6 KIK49541.1 - 0.13 12.4 5.2 0.26 11.4 5.2 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator NOA36 PF06524.12 KIK49541.1 - 2.7 7.2 6.5 4.6 6.5 6.5 1.2 1 0 0 1 1 1 0 NOA36 protein AIM3 PF17096.5 KIK49541.1 - 2.8 8.9 8.2 8.4 7.4 7.2 2.2 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 PBP1_TM PF14812.6 KIK49541.1 - 3.6 8.0 9.0 12 6.4 9.0 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RINT1_TIP1 PF04437.13 KIK49543.1 - 1.3e-89 301.4 0.9 1.3e-89 301.4 0.1 1.4 2 0 0 2 2 2 1 RINT-1 / TIP-1 family CNOT11 PF10155.9 KIK49543.1 - 0.022 14.9 0.0 0.056 13.6 0.0 1.6 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 11 BLUF PF04940.12 KIK49543.1 - 0.13 12.5 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 Sensors of blue-light using FAD Pro_CA PF00484.19 KIK49544.1 - 1e-14 55.1 0.1 3.3e-14 53.5 0.1 1.7 1 1 0 1 1 1 1 Carbonic anhydrase NT5C PF06941.12 KIK49545.1 - 2.8e-06 27.3 0.1 2.9e-05 24.0 0.0 2.5 3 1 0 3 3 3 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) ABC_membrane_2 PF06472.15 KIK49546.1 - 9.8e-84 280.9 1.0 1.4e-83 280.4 1.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KIK49546.1 - 2.5e-17 63.7 0.0 5.9e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIK49546.1 - 5.7e-05 23.1 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIK49546.1 - 0.0015 18.2 0.0 0.0037 17.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KIK49546.1 - 0.0042 17.6 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 KIK49546.1 - 0.011 15.2 0.0 0.053 13.0 0.0 2.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 KIK49546.1 - 0.064 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIK49546.1 - 0.13 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PRELI PF04707.14 KIK49547.1 - 1.5e-38 132.1 0.0 1.8e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family TFIIB PF00382.19 KIK49548.1 - 2.5e-38 129.9 0.9 3.9e-18 65.3 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KIK49548.1 - 1.5e-27 95.9 8.1 9.2e-27 93.4 1.0 2.5 2 0 0 2 2 2 2 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 KIK49548.1 - 6.4e-09 35.2 3.6 1.4e-08 34.1 3.6 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KIK49548.1 - 4.4e-05 23.2 1.1 0.044 13.5 0.3 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain DZR PF12773.7 KIK49548.1 - 0.023 14.7 0.3 0.044 13.8 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon DUF4145 PF13643.6 KIK49548.1 - 0.14 12.3 0.1 0.37 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) zf-RRN7 PF11781.8 KIK49548.1 - 0.4 10.4 2.7 0.73 9.6 2.7 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Pkinase PF00069.25 KIK49550.1 - 6.1e-66 222.5 0.0 1.1e-65 221.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK49550.1 - 4.8e-36 124.4 0.0 1e-26 93.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIK49550.1 - 1.9e-06 27.4 0.1 1.4e-05 24.5 0.1 2.1 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIK49550.1 - 0.0018 17.1 0.0 0.0043 15.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIK49550.1 - 0.0036 17.3 0.1 0.011 15.7 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KIK49550.1 - 0.032 13.3 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 KIK49550.1 - 0.13 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SPX PF03105.19 KIK49550.1 - 1.1 9.1 4.7 1.9 8.3 4.7 1.3 1 0 0 1 1 1 0 SPX domain MMR_HSR1_Xtn PF16897.5 KIK49551.1 - 5.7e-42 142.0 1.7 1.1e-41 141.1 1.7 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KIK49551.1 - 2.5e-17 63.0 0.1 7.7e-17 61.4 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KIK49551.1 - 3.3e-17 62.3 0.0 5.6e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KIK49551.1 - 5.9e-09 35.6 0.0 1.7e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KIK49551.1 - 0.063 13.7 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 KIK49551.1 - 0.076 12.1 0.0 0.24 10.4 0.0 1.8 2 0 0 2 2 2 0 MCM P-loop domain Lactamase_B_2 PF12706.7 KIK49552.1 - 1.3e-27 96.7 0.0 4e-25 88.5 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIK49552.1 - 8.7e-06 25.9 0.2 1.4e-05 25.2 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PIN PF01850.21 KIK49552.1 - 0.034 14.7 0.0 0.14 12.7 0.0 2.0 2 0 0 2 2 2 0 PIN domain PRELI PF04707.14 KIK49553.1 - 3.1e-33 114.8 0.0 4e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family Phage_T4_Ndd PF06591.11 KIK49553.1 - 0.014 15.2 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) RIC1 PF07064.13 KIK49554.1 - 2e-101 338.6 0.6 2.8e-101 338.2 0.6 1.2 1 0 0 1 1 1 1 RIC1 PD40 PF07676.12 KIK49554.1 - 3.1e-06 27.0 2.7 0.011 15.6 0.0 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 KIK49554.1 - 0.0066 16.7 0.1 0.56 10.5 0.0 3.6 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DIOX_N PF14226.6 KIK49555.1 - 3.2e-05 24.7 0.0 5.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIK49555.1 - 0.00038 20.9 0.0 0.0026 18.2 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_transf_28 PF03033.20 KIK49556.1 - 2.4e-31 108.6 0.0 5.7e-31 107.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 KIK49556.1 - 5.3e-24 84.3 2.0 9.5e-14 51.3 0.0 3.5 3 0 0 3 3 3 3 GRAM domain PH PF00169.29 KIK49556.1 - 1.3e-12 48.2 0.2 2.1e-11 44.2 0.4 2.5 2 0 0 2 2 2 1 PH domain UDPGT PF00201.18 KIK49556.1 - 0.00024 20.0 0.0 0.00054 18.9 0.0 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.6 KIK49556.1 - 0.00067 20.1 2.1 0.074 13.5 2.1 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 KIK49556.1 - 0.039 14.2 0.0 0.098 13.0 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain eIF_4G1 PF12152.8 KIK49556.1 - 0.1 12.8 0.4 0.27 11.4 0.4 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4G1 SUR7 PF06687.12 KIK49557.1 - 1.2e-15 57.8 13.1 1.5e-15 57.4 13.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF5480 PF17576.2 KIK49557.1 - 0.73 9.8 5.5 6.6 6.8 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5480) zf-C2H2 PF00096.26 KIK49558.1 - 8.6e-09 35.4 15.4 2.5e-06 27.6 0.3 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIK49558.1 - 6.8e-07 29.6 15.1 0.00028 21.4 0.2 3.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIK49558.1 - 3.5e-05 24.0 11.9 0.027 14.9 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 KIK49558.1 - 0.0024 17.8 10.7 0.0078 16.2 0.0 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf_ZIC PF18366.1 KIK49558.1 - 0.0054 16.8 0.9 1.3 9.2 0.3 2.3 2 0 0 2 2 2 2 Zic proteins zinc finger domain zf-C2H2_jaz PF12171.8 KIK49558.1 - 0.033 14.5 1.2 0.64 10.4 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding TRAF6_Z2 PF18048.1 KIK49558.1 - 0.11 12.6 0.9 0.21 11.7 0.1 1.9 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-Di19 PF05605.12 KIK49558.1 - 0.16 12.3 4.6 0.35 11.2 4.6 1.6 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Nudix_N_2 PF14803.6 KIK49558.1 - 0.86 9.6 8.2 8.2 6.4 1.0 3.1 3 0 0 3 3 3 0 Nudix N-terminal Catalase PF00199.19 KIK49559.1 - 7.3e-170 565.2 0.1 1e-169 564.7 0.1 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KIK49559.1 - 2.7e-18 65.9 0.0 5.5e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 KIK49559.1 - 1.7e-12 47.2 0.0 3.2e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 KIK49559.1 - 1.1e-08 35.0 0.0 2.2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family Nramp PF01566.18 KIK49560.1 - 7.7e-86 288.3 19.8 2.5e-51 174.8 2.5 2.5 3 0 0 3 3 3 2 Natural resistance-associated macrophage protein Med6 PF04934.14 KIK49561.1 - 1.6e-40 138.0 0.1 1.6e-40 138.0 0.1 1.4 2 0 0 2 2 2 1 MED6 mediator sub complex component Clat_adaptor_s PF01217.20 KIK49562.1 - 5e-43 146.4 0.1 1.8e-42 144.6 0.1 1.7 1 1 0 1 1 1 1 Clathrin adaptor complex small chain SGT1 PF07093.11 KIK49563.1 - 7.8e-96 321.8 21.5 1.2e-58 199.1 13.6 3.9 3 1 0 3 3 3 3 SGT1 protein ATP-synt_F PF01990.17 KIK49564.1 - 4.2e-33 113.5 0.2 5e-33 113.3 0.2 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.6 KIK49564.1 - 0.015 14.5 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase PIN_8 PF18476.1 KIK49564.1 - 0.044 13.7 0.1 0.053 13.4 0.1 1.1 1 0 0 1 1 1 0 PIN like domain DUF2759 PF10958.8 KIK49564.1 - 0.18 11.5 0.0 2.3 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) TIM21 PF08294.11 KIK49565.1 - 1.4e-23 83.4 0.0 2.7e-21 75.9 0.0 2.4 2 0 0 2 2 2 2 TIM21 Histone PF00125.24 KIK49566.1 - 1.3e-49 167.9 2.7 1.5e-49 167.7 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KIK49566.1 - 2.6e-05 24.5 0.1 4.1e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KIK49566.1 - 8.5e-05 22.6 1.0 9.9e-05 22.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KIK49566.1 - 0.00058 20.1 0.8 0.0014 18.9 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 KIK49566.1 - 0.0021 18.7 1.9 0.0026 18.3 1.9 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain TFIID-31kDa PF02291.15 KIK49566.1 - 0.088 12.9 0.2 0.17 11.9 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KIK49566.1 - 0.088 12.8 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated Guanylate_cyc PF00211.20 KIK49568.1 - 3.1e-21 75.8 0.0 5e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Chalcone_2 PF16035.5 KIK49569.1 - 4.3e-31 108.3 0.2 1.8e-19 70.4 0.0 2.2 1 1 1 2 2 2 2 Chalcone isomerase like BLM10_mid PF16507.5 KIK49570.1 - 4.2e-185 616.3 0.0 1.1e-184 615.0 0.0 1.7 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KIK49570.1 - 2.1e-32 110.8 0.5 2.7e-31 107.3 0.1 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.6 KIK49570.1 - 1.7e-05 25.1 0.6 0.0081 16.5 0.0 5.2 6 0 0 6 6 6 1 HEAT repeats HEAT PF02985.22 KIK49570.1 - 0.00012 22.0 8.3 0.038 14.2 0.1 6.3 6 0 0 6 6 6 1 HEAT repeat BLM10_N PF16547.5 KIK49570.1 - 0.065 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal zf-CCCH PF00642.24 KIK49572.1 - 6.1e-19 67.5 13.6 8.6e-11 41.5 2.6 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIK49572.1 - 2.2e-08 33.9 13.7 2.4e-06 27.4 3.8 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KIK49572.1 - 2.4e-08 33.6 11.0 5.8e-06 26.0 0.9 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KIK49572.1 - 0.019 15.4 8.1 0.084 13.4 0.2 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KIK49572.1 - 0.2 12.4 10.1 1.1 10.0 2.0 2.5 1 1 1 2 2 2 0 Torus domain DUF4357 PF14267.6 KIK49572.1 - 0.47 10.4 3.0 17 5.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) Defensin_int PF17858.1 KIK49572.1 - 4.1 7.5 5.5 0.71 9.9 1.3 1.9 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide Choline_kinase PF01633.20 KIK49574.1 - 4.4e-51 173.5 0.0 9.8e-51 172.3 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KIK49574.1 - 1e-10 42.0 0.1 1.7e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KIK49574.1 - 0.0095 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase MFS_1 PF07690.16 KIK49577.1 - 5.8e-45 153.7 74.7 4e-40 137.8 48.4 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIK49577.1 - 2.5e-15 55.9 13.1 2.5e-15 55.9 13.1 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIK49577.1 - 8.8e-14 51.2 11.1 8.8e-14 51.2 11.1 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter LRR19-TM PF15176.6 KIK49577.1 - 0.031 14.3 0.7 0.18 11.8 0.0 2.5 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain DnaJ_C PF01556.18 KIK49578.1 - 2.2e-37 128.4 0.0 3.1e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIK49578.1 - 2.5e-23 82.0 2.6 3.9e-23 81.3 2.6 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KIK49578.1 - 4.7e-09 36.5 15.2 5.1e-09 36.4 13.9 1.8 1 1 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KIK49578.1 - 0.056 13.4 15.3 0.1 12.6 2.3 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF2318 PF10080.9 KIK49578.1 - 0.99 9.6 4.1 1.7 8.8 1.8 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) SET PF00856.28 KIK49579.1 - 0.00093 19.6 0.0 0.0026 18.2 0.0 1.4 1 1 0 1 1 1 1 SET domain Pkinase PF00069.25 KIK49580.1 - 1.9e-58 197.9 0.1 2.4e-58 197.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIK49580.1 - 1.3e-15 57.4 0.0 2e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIK49580.1 - 8.5e-08 32.4 0.0 7.6e-06 26.0 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KIK49580.1 - 0.0081 15.5 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIK49580.1 - 0.01 14.6 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 KIK49580.1 - 0.022 14.3 0.1 0.042 13.4 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase DNA_pol_A_exo1 PF01612.20 KIK49581.1 - 5.6e-11 42.4 0.0 7.1e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease zf-C3HC4_2 PF13923.6 KIK49584.1 - 5.6e-07 29.3 9.9 1.7e-06 27.7 10.3 1.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIK49584.1 - 1.9e-06 27.6 9.0 2.7e-06 27.1 9.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIK49584.1 - 2.2e-06 27.9 11.1 3.6e-06 27.2 11.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIK49584.1 - 4.1e-05 23.4 10.8 6.5e-05 22.7 10.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIK49584.1 - 7.1e-05 22.7 5.8 0.00028 20.8 5.9 1.9 1 1 1 2 2 2 1 RING-type zinc-finger Baculo_IE-1 PF05290.11 KIK49584.1 - 0.14 12.1 2.2 0.21 11.5 2.2 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) FYVE PF01363.21 KIK49584.1 - 0.19 11.9 5.8 0.41 10.8 5.8 1.5 1 0 0 1 1 1 0 FYVE zinc finger Prok-RING_4 PF14447.6 KIK49584.1 - 0.35 10.8 13.1 0.064 13.1 6.4 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KIK49584.1 - 1 9.4 10.5 6.3 6.8 11.2 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KIK49584.1 - 1.1 9.5 11.1 2.2 8.5 11.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-WRNIP1_ubi PF18279.1 KIK49584.1 - 1.5 9.6 5.5 0.57 10.9 1.8 2.2 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-B_box PF00643.24 KIK49584.1 - 3.6 7.8 9.2 0.47 10.6 4.9 1.8 1 1 0 1 1 1 0 B-box zinc finger Translin PF01997.16 KIK49586.1 - 5.6e-70 235.5 0.2 7e-70 235.2 0.2 1.1 1 0 0 1 1 1 1 Translin family MRFAP1 PF15155.6 KIK49586.1 - 0.014 15.9 0.1 0.061 13.8 0.0 2.0 2 1 0 2 2 2 0 MORF4 family-associated protein1 DcpS_C PF11969.8 KIK49587.1 - 9.4e-05 22.9 0.2 0.00024 21.5 0.2 1.6 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF3875 PF12991.7 KIK49587.1 - 0.0013 18.6 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function, B. Theta Gene description (DUF3875) BLM10_mid PF16507.5 KIK49588.1 - 2.7e-193 643.4 0.2 4.2e-193 642.8 0.2 1.3 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KIK49588.1 - 6.1e-28 96.6 0.5 7.1e-27 93.2 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) HEAT PF02985.22 KIK49588.1 - 3.2e-06 26.9 8.9 0.47 10.9 0.1 7.0 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 KIK49588.1 - 0.00042 20.6 0.3 2.6 8.5 0.0 5.5 5 0 0 5 5 5 1 HEAT repeats BLM10_N PF16547.5 KIK49588.1 - 0.0035 17.6 0.1 0.012 15.9 0.1 2.0 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal DUF4119 PF13494.6 KIK49588.1 - 0.017 15.3 0.0 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) DUF3907 PF13047.6 KIK49588.1 - 0.34 10.9 1.4 4.7 7.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3907) RXT2_N PF08595.11 KIK49589.1 - 2.9 7.9 6.1 6.9 6.7 0.0 2.3 1 1 1 2 2 2 0 RXT2-like, N-terminal BATS PF06968.13 KIK49590.1 - 3.9e-21 75.0 0.1 1.4e-20 73.2 0.0 2.0 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KIK49590.1 - 1.6e-16 61.1 0.0 2.3e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily BTG PF07742.12 KIK49592.1 - 7.4e-15 54.8 0.0 1.9e-14 53.5 0.0 1.6 2 0 0 2 2 2 1 BTG family Ribosomal_S27e PF01667.17 KIK49593.1 - 4.9e-28 96.6 1.5 5.8e-28 96.4 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 DUF3795 PF12675.7 KIK49593.1 - 0.038 14.4 0.9 0.24 11.8 0.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) TF_Zn_Ribbon PF08271.12 KIK49593.1 - 0.19 11.3 1.7 0.29 10.7 1.7 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding Mu-like_Com PF10122.9 KIK49593.1 - 0.34 10.4 3.1 6.8 6.2 0.5 2.3 1 1 1 2 2 2 0 Mu-like prophage protein Com Macoilin PF09726.9 KIK49595.1 - 1.3 7.5 4.2 1.8 7.0 4.2 1.1 1 0 0 1 1 1 0 Macoilin family 4HBT_3 PF13622.6 KIK49596.1 - 3.9e-30 105.9 0.0 5e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily XPA_C PF05181.12 KIK49597.1 - 1.3e-25 89.1 0.9 2.4e-25 88.3 0.9 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 KIK49597.1 - 2.8e-05 24.0 5.8 2.8e-05 24.0 5.8 2.6 3 0 0 3 3 3 1 XPA protein N-terminal PhnA_Zn_Ribbon PF08274.12 KIK49597.1 - 1.2 9.1 8.5 0.48 10.4 3.3 2.7 2 1 0 2 2 2 0 PhnA Zinc-Ribbon ArfGap PF01412.18 KIK49597.1 - 4.7 7.3 7.4 0.49 10.5 0.6 2.5 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf Rubredoxin_2 PF18073.1 KIK49597.1 - 9 6.1 7.5 18 5.1 0.2 3.4 3 0 0 3 3 3 0 Rubredoxin metal binding domain Hist_deacetyl PF00850.19 KIK49598.1 - 6.4e-86 288.6 0.0 8.4e-86 288.2 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain NIL PF09383.10 KIK49598.1 - 0.21 11.5 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 NIL domain DinB_2 PF12867.7 KIK49599.1 - 5.3e-09 36.7 0.2 6.7e-09 36.3 0.2 1.1 1 0 0 1 1 1 1 DinB superfamily ATP-grasp_2 PF08442.10 KIK49601.1 - 2.1e-70 236.4 1.1 2.7e-70 236.0 0.3 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KIK49601.1 - 3.2e-25 88.7 0.5 6.3e-25 87.8 0.5 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KIK49601.1 - 6.8e-09 35.5 0.7 3.3e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KIK49601.1 - 9.5e-05 22.2 0.0 0.00028 20.7 0.0 1.8 1 1 1 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain PASTA PF03793.19 KIK49601.1 - 0.14 12.1 1.2 23 4.9 0.1 3.1 3 0 0 3 3 3 0 PASTA domain DUF1682 PF07946.14 KIK49602.1 - 0.061 12.5 1.6 0.11 11.7 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CCSAP PF15748.5 KIK49602.1 - 9 6.4 16.0 0.038 14.2 5.3 2.5 3 0 0 3 3 3 0 Centriole, cilia and spindle-associated BCAS2 PF05700.11 KIK49603.1 - 4e-68 229.2 8.7 4.5e-68 229.0 8.7 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Mesd PF10185.9 KIK49603.1 - 0.00079 19.4 0.0 0.0015 18.5 0.0 1.6 2 0 0 2 2 2 1 Chaperone for wingless signalling and trafficking of LDL receptor ACT PF01842.25 KIK49603.1 - 0.069 12.9 0.0 11 6.0 0.0 2.4 2 0 0 2 2 2 0 ACT domain CLZ PF16526.5 KIK49603.1 - 3.8 7.9 8.9 0.17 12.3 1.4 2.5 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels APG6_N PF17675.1 KIK49603.1 - 4.9 7.7 11.3 1.6 9.3 7.1 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 KIK49603.1 - 8.9 6.2 11.3 6.9 6.5 0.6 2.8 3 0 0 3 3 3 0 Septum formation initiator Complex1_30kDa PF00329.19 KIK49604.1 - 2.3e-46 157.4 0.0 3.2e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF5427 PF10310.9 KIK49605.1 - 3.6e-57 194.3 4.4 4.6e-53 180.8 0.1 2.1 1 1 1 2 2 2 2 Family of unknown function (DUF5427) Chromo PF00385.24 KIK49606.1 - 6e-11 42.1 2.4 1.3e-10 41.0 2.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 KIK49606.1 - 0.043 13.7 2.5 0.085 12.8 2.5 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF4551 PF15087.6 KIK49606.1 - 6.9 5.4 14.7 12 4.5 14.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Tim17 PF02466.19 KIK49607.1 - 9.3e-11 42.1 0.5 9.3e-11 42.1 0.5 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 KIK49607.1 - 0.42 10.8 3.4 11 6.1 0.1 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5518) Herpes_UL42 PF02282.16 KIK49608.1 - 0.037 13.9 0.0 0.053 13.4 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase processivity factor (UL42) PADR1 PF08063.12 KIK49608.1 - 0.085 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 PADR1 (NUC008) domain Ras PF00071.22 KIK49609.1 - 4.6e-50 169.4 0.1 5.3e-50 169.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIK49609.1 - 2.4e-18 66.5 0.0 3.2e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIK49609.1 - 5.5e-05 22.7 0.0 6.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIK49609.1 - 0.0045 16.5 0.0 0.015 14.9 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIK49609.1 - 0.012 15.6 0.2 0.49 10.3 0.0 2.1 1 1 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 KIK49609.1 - 0.024 14.7 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Yippee-Mis18 PF03226.14 KIK49614.1 - 1.2e-16 60.8 0.1 1.4e-16 60.6 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2039 PF10217.9 KIK49614.1 - 0.012 16.0 0.8 1 9.8 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) GFA PF04828.14 KIK49614.1 - 0.029 14.7 0.9 0.61 10.5 1.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Endonuclease_7 PF02945.15 KIK49614.1 - 0.1 12.6 0.7 0.19 11.7 0.7 1.7 1 1 0 1 1 1 0 Recombination endonuclease VII CSTF1_dimer PF16699.5 KIK49615.1 - 0.16 11.7 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain NUDIX PF00293.28 KIK49616.1 - 2.4e-07 30.8 0.0 4.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NPL4 PF05021.15 KIK49617.1 - 3.4e-102 341.9 0.0 4.5e-102 341.5 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KIK49617.1 - 1.4e-63 213.4 0.0 2.2e-63 212.7 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KIK49617.1 - 4.7e-07 30.2 0.0 9.7e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zinc_ribbon_2 PF13240.6 KIK49617.1 - 0.024 14.4 2.5 0.024 14.4 2.5 2.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-RanBP PF00641.18 KIK49617.1 - 0.19 11.1 0.5 0.37 10.1 0.5 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others bZIP_2 PF07716.15 KIK49618.1 - 4.1e-10 39.6 9.7 2e-08 34.2 9.8 2.4 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 KIK49618.1 - 6e-06 26.3 5.8 1.1e-05 25.4 5.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor CCDC85 PF10226.9 KIK49618.1 - 0.00014 21.6 0.9 0.00014 21.6 0.9 1.8 3 0 0 3 3 3 1 CCDC85 family bZIP_Maf PF03131.17 KIK49618.1 - 0.04 14.4 3.4 0.04 14.4 3.4 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor CHCH PF06747.13 KIK49619.1 - 6.6e-06 26.1 4.5 1e-05 25.5 4.5 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KIK49619.1 - 0.00092 19.2 2.7 0.0013 18.7 2.7 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 KIK49619.1 - 0.0091 15.7 0.8 0.012 15.4 0.8 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 KIK49619.1 - 0.13 12.6 4.1 0.25 11.7 4.1 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 KIK49619.1 - 1 9.7 4.6 1.7 9.1 1.2 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) GDPD PF03009.17 KIK49620.1 - 3.7e-34 118.6 0.0 4.5e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KIK49620.1 - 0.00053 20.4 0.3 0.017 15.5 0.1 2.5 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family 5_nucleotid PF05761.14 KIK49622.1 - 0.13 11.1 0.2 0.15 10.9 0.2 1.0 1 0 0 1 1 1 0 5' nucleotidase family Rieske PF00355.26 KIK49625.1 - 5.6e-11 42.2 0.0 9.1e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KIK49625.1 - 5.9e-09 36.3 0.7 1.4e-08 35.1 0.7 1.6 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Pkinase PF00069.25 KIK49626.1 - 1e-44 152.9 0.0 9.9e-27 93.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK49626.1 - 4.9e-34 117.8 0.0 7.8e-20 71.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK49626.1 - 0.00048 19.0 0.0 0.00087 18.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Choline_sulf_C PF12411.8 KIK49626.1 - 0.0023 17.7 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Kinase-like PF14531.6 KIK49626.1 - 0.13 11.6 0.0 0.6 9.4 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.25 KIK49627.1 - 2.4e-41 141.8 0.0 2.5e-21 76.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIK49627.1 - 2.7e-12 46.5 0.0 8.5e-08 31.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIK49627.1 - 0.00072 18.4 0.1 0.0022 16.9 0.1 1.5 1 1 0 1 1 1 1 Fungal protein kinase p450 PF00067.22 KIK49628.1 - 2.2e-53 181.7 0.0 4.6e-52 177.3 0.0 2.5 1 1 0 1 1 1 1 Cytochrome P450 DUF2732 PF10809.8 KIK49628.1 - 0.25 11.3 1.9 1.6 8.6 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2732) SprT-like PF10263.9 KIK49629.1 - 6.5e-31 106.5 0.7 9.7e-31 106.0 0.7 1.3 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 KIK49629.1 - 0.015 15.2 2.1 0.037 13.9 2.1 1.7 1 0 0 1 1 1 0 SprT-like zinc ribbon domain SOTI PF17079.5 KIK49629.1 - 0.065 13.6 0.0 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 Male-specific protein scotti Pyr_redox_2 PF07992.14 KIK49631.1 - 4.8e-51 173.7 0.1 5.6e-51 173.5 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIK49631.1 - 1.2e-17 64.3 0.4 9.9e-15 54.9 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIK49631.1 - 4.1e-16 59.1 0.1 1.9e-12 47.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIK49631.1 - 3.3e-06 26.5 0.0 0.0001 21.6 0.0 2.4 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KIK49631.1 - 3e-05 23.8 1.0 0.098 12.2 0.3 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIK49631.1 - 4.5e-05 23.6 0.5 0.0032 17.6 0.0 2.6 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KIK49631.1 - 9.3e-05 21.8 0.2 0.012 14.9 0.0 2.9 2 1 1 3 3 3 1 FAD binding domain GIDA PF01134.22 KIK49631.1 - 0.00013 21.2 6.5 0.0075 15.4 0.1 4.1 4 1 1 5 5 5 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KIK49631.1 - 0.00058 19.1 1.3 0.017 14.2 0.2 2.6 3 0 0 3 3 3 1 FAD binding domain Shikimate_DH PF01488.20 KIK49631.1 - 0.00071 19.6 0.3 3.9 7.6 0.0 3.5 3 1 1 4 4 4 2 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KIK49631.1 - 0.00089 19.7 0.0 0.11 13.0 0.0 2.8 2 2 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.7 KIK49631.1 - 0.0011 18.4 0.1 0.014 14.8 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase F420_oxidored PF03807.17 KIK49631.1 - 0.013 16.0 0.0 1.4 9.6 0.0 3.0 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent K_oxygenase PF13434.6 KIK49631.1 - 0.016 14.3 0.2 1.6 7.8 0.0 3.1 2 1 1 4 4 4 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KIK49631.1 - 0.018 13.9 0.2 0.069 12.0 0.1 1.9 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 KIK49631.1 - 0.024 13.4 2.1 0.17 10.6 0.5 2.7 3 0 0 3 3 3 0 HI0933-like protein ApbA PF02558.16 KIK49631.1 - 0.029 14.0 0.6 9.2 5.9 0.0 2.7 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA MCM PF00493.23 KIK49632.1 - 2.8e-102 340.6 0.0 5.5e-102 339.6 0.0 1.5 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KIK49632.1 - 2.6e-34 117.8 0.0 5.6e-34 116.7 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KIK49632.1 - 1.7e-30 105.2 0.6 3.9e-30 104.1 0.6 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KIK49632.1 - 1.3e-15 57.9 0.0 3.3e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KIK49632.1 - 7e-07 28.8 0.0 0.00023 20.6 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KIK49632.1 - 7.7e-05 22.7 0.0 0.00018 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KIK49632.1 - 0.0002 21.2 0.1 0.0014 18.4 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 KIK49632.1 - 0.0064 17.1 0.4 0.089 13.4 0.1 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI C-terminal AAA PF00004.29 KIK49632.1 - 0.099 13.1 0.0 0.32 11.4 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MitMem_reg PF13012.6 KIK49633.1 - 1e-25 90.3 0.0 1.8e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KIK49633.1 - 2.9e-13 49.8 0.0 4.9e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4149 PF13664.6 KIK49634.1 - 7.4e-19 68.0 2.6 7.4e-19 68.0 2.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) LRR_9 PF14580.6 KIK49635.1 - 7.4e-62 207.9 0.0 2.9e-61 206.0 0.0 1.7 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 KIK49635.1 - 1.5e-09 37.9 14.8 8.7e-07 29.2 1.5 3.8 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIK49635.1 - 1.2e-06 28.2 2.0 2.5e-06 27.1 0.6 2.3 3 0 0 3 3 3 1 Leucine rich repeat Syja_N PF02383.18 KIK49636.1 - 5e-84 282.3 0.0 6.4e-84 282.0 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain VirB3 PF05101.13 KIK49636.1 - 0.23 11.7 4.9 0.57 10.5 4.9 1.6 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein NAP PF00956.18 KIK49637.1 - 8.9e-21 74.3 8.5 2e-19 69.8 3.2 3.1 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Astro_capsid_p PF12226.8 KIK49637.1 - 0.29 10.2 5.6 0.21 10.7 4.4 1.4 2 0 0 2 2 2 0 Turkey astrovirus capsid protein p450 PF00067.22 KIK49639.1 - 9.4e-64 215.8 0.0 1.3e-63 215.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF913 PF06025.12 KIK49639.1 - 0.045 12.7 0.0 0.066 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PE PF00934.20 KIK49639.1 - 0.1 12.9 0.2 0.3 11.4 0.2 1.7 1 1 0 1 1 1 0 PE family Acatn PF13000.7 KIK49640.1 - 7.3e-146 486.9 26.6 1e-69 235.5 15.5 3.5 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DUF3611 PF12263.8 KIK49640.1 - 0.032 14.1 0.6 0.032 14.1 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3611) GYF PF02213.16 KIK49641.1 - 1.5e-16 59.8 0.4 4.9e-16 58.1 0.6 1.8 2 0 0 2 2 2 1 GYF domain GYF_2 PF14237.6 KIK49641.1 - 0.029 14.2 0.1 0.079 12.8 0.1 1.8 1 0 0 1 1 1 0 GYF domain 2 BAG PF02179.16 KIK49642.1 - 4.7e-05 23.7 2.0 0.00084 19.7 0.0 3.1 3 0 0 3 3 3 1 BAG domain DUF3791 PF12668.7 KIK49642.1 - 0.014 15.5 0.1 0.023 14.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) Band_7 PF01145.25 KIK49643.1 - 4.7e-25 88.6 4.0 1.2e-24 87.3 4.0 1.7 1 1 0 1 1 1 1 SPFH domain / Band 7 family RRM_1 PF00076.22 KIK49644.1 - 1.4e-51 172.2 0.0 1.9e-16 59.7 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIK49644.1 - 1.4e-09 37.6 0.0 4.1e-05 23.2 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIK49644.1 - 2.5e-06 27.3 0.0 0.00026 20.8 0.0 2.9 3 0 0 3 3 3 1 Occluded RNA-recognition motif Cas_Cas2CT1978 PF09707.10 KIK49644.1 - 0.0035 17.4 0.0 3.9 7.6 0.0 2.5 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) Nup35_RRM_2 PF14605.6 KIK49644.1 - 0.06 13.4 0.1 27 4.9 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KIK49644.1 - 0.13 12.4 0.0 2.4 8.3 0.0 2.8 3 1 0 3 3 3 0 RNA recognition motif ATG16 PF08614.11 KIK49645.1 - 1.7e-53 181.8 26.8 2.1e-53 181.5 26.8 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 KIK49645.1 - 0.012 15.9 25.0 0.12 12.6 2.0 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Alpha-2-MRAP_C PF06401.11 KIK49645.1 - 0.018 15.0 10.0 0.018 15.0 10.0 1.8 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain PilW PF16074.5 KIK49645.1 - 0.053 13.5 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Type IV Pilus-assembly protein W NDUF_B6 PF09782.9 KIK49645.1 - 0.095 12.8 1.4 5.3 7.2 0.6 2.4 1 1 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit YabA PF06156.13 KIK49645.1 - 0.2 12.3 18.2 0.11 13.2 3.9 3.2 1 1 2 3 3 3 0 Initiation control protein YabA LURAP PF14854.6 KIK49645.1 - 0.2 11.6 3.0 1.3 9.0 0.1 2.9 1 1 2 3 3 3 0 Leucine rich adaptor protein FlaC_arch PF05377.11 KIK49645.1 - 0.31 11.4 3.5 15 6.1 0.1 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) SOGA PF11365.8 KIK49645.1 - 0.41 11.8 16.4 0.11 13.6 4.9 3.2 2 1 1 3 3 3 0 Protein SOGA Rootletin PF15035.6 KIK49645.1 - 0.8 9.7 25.6 2.2 8.2 10.3 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion MAD PF05557.13 KIK49645.1 - 0.88 7.9 22.3 0.21 9.9 17.0 1.9 2 0 0 2 2 2 0 Mitotic checkpoint protein FAD_SOX PF18371.1 KIK49645.1 - 0.96 9.8 5.2 4.5 7.7 0.5 2.7 2 1 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase MPS2 PF17060.5 KIK49645.1 - 1.3 8.3 9.7 3.2 6.9 0.7 2.2 1 1 1 2 2 2 0 Monopolar spindle protein 2 Fez1 PF06818.15 KIK49645.1 - 1.5 9.3 18.2 9.8 6.6 15.1 2.3 1 1 1 2 2 2 0 Fez1 Fib_alpha PF08702.10 KIK49645.1 - 3.4 7.8 15.8 1.3 9.2 2.5 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 KIK49645.1 - 5.8 6.2 16.1 12 5.1 15.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 KIK49645.1 - 5.9 7.4 26.2 2.7 8.5 5.0 4.1 2 1 1 3 3 3 0 Cell division protein ZapB ING PF12998.7 KIK49645.1 - 6.7 7.4 12.1 1.6 9.4 1.6 3.1 2 1 2 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding DUF16 PF01519.16 KIK49645.1 - 9.8 6.7 12.9 0.45 11.0 5.5 2.3 2 1 1 3 3 3 0 Protein of unknown function DUF16 Arm PF00514.23 KIK49647.1 - 1.4e-69 228.2 32.0 7.8e-13 48.0 0.1 11.6 11 1 1 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KIK49647.1 - 9.7e-18 64.3 12.9 0.00093 19.6 0.3 7.6 5 2 3 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 KIK49647.1 - 1e-15 57.8 8.1 0.028 14.8 0.0 6.7 4 3 1 6 6 6 4 HEAT repeats HEAT PF02985.22 KIK49647.1 - 9.1e-14 50.4 14.7 0.4 11.1 0.1 9.2 9 0 0 9 9 9 5 HEAT repeat Arm_2 PF04826.13 KIK49647.1 - 2.6e-11 43.5 12.0 6.4e-08 32.4 2.7 2.5 1 1 1 2 2 2 2 Armadillo-like Adaptin_N PF01602.20 KIK49647.1 - 8.7e-10 37.8 10.4 2e-07 30.0 0.3 2.3 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.12 KIK49647.1 - 8.9e-10 37.4 1.9 1.3e-09 36.8 1.9 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 KIK49647.1 - 2.5e-07 30.3 11.3 0.0018 17.6 0.7 4.4 1 1 2 4 4 4 3 V-ATPase subunit H Cnd1 PF12717.7 KIK49647.1 - 4.2e-06 26.9 7.8 0.0053 16.8 0.2 4.7 1 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 KIK49647.1 - 0.00076 19.4 8.5 0.9 9.5 0.0 4.0 1 1 1 3 3 3 2 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 KIK49647.1 - 0.01 15.9 6.7 33 4.6 0.1 5.1 1 1 5 6 6 6 0 V-ATPase subunit H HEAT_PBS PF03130.16 KIK49647.1 - 0.028 15.1 10.5 56 4.8 0.2 7.2 8 0 0 8 8 7 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 KIK49647.1 - 0.033 14.8 0.2 9.6 6.9 0.1 3.4 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 KIK49647.1 - 0.055 13.6 1.6 51 4.1 0.0 3.8 2 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Atx10homo_assoc PF09759.9 KIK49647.1 - 0.33 11.0 4.8 0.46 10.5 0.2 3.4 3 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain Glyco_hydro_16 PF00722.21 KIK49649.1 - 8.3e-08 31.9 0.1 3.5e-07 29.9 0.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Asn_synthase PF00733.21 KIK49650.1 - 3.2e-19 69.8 1.0 2.9e-08 33.8 0.0 3.4 2 2 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 KIK49650.1 - 3.7e-06 26.8 0.0 9e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain QueC PF06508.13 KIK49650.1 - 0.0041 16.6 0.0 0.029 13.9 0.0 2.0 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC GATase_6 PF13522.6 KIK49650.1 - 0.15 12.3 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase domain NAD_synthase PF02540.17 KIK49650.1 - 0.15 11.1 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 NAD synthase 6PGD PF00393.19 KIK49651.1 - 2.2e-124 414.6 0.0 2.6e-124 414.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KIK49651.1 - 2.7e-51 173.9 0.0 3.9e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KIK49651.1 - 0.0018 18.9 0.0 0.0036 17.9 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KIK49651.1 - 0.034 13.8 0.1 0.067 12.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CoatB PF10389.9 KIK49651.1 - 4 7.4 5.8 28 4.6 2.0 2.4 2 0 0 2 2 2 0 Bacteriophage coat protein B Oxysterol_BP PF01237.18 KIK49652.1 - 5.3e-113 377.6 0.1 2.8e-112 375.2 0.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KIK49652.1 - 1.6e-16 60.3 0.1 1.7e-15 57.0 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KIK49652.1 - 8.9e-06 26.2 0.2 5.8e-05 23.5 0.2 2.2 1 1 0 1 1 1 1 PH domain DUF234 PF03008.14 KIK49652.1 - 0.0029 18.1 0.0 0.2 12.1 0.0 2.5 2 0 0 2 2 2 1 Archaea bacterial proteins of unknown function Aconitase PF00330.20 KIK49654.1 - 2.1e-154 514.9 0.0 2.7e-154 514.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KIK49654.1 - 6.9e-34 117.0 0.0 1.2e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KIK49654.1 - 0.024 13.3 0.0 0.12 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF521) MutS_V PF00488.21 KIK49655.1 - 3.5e-71 239.2 0.1 1.1e-70 237.5 0.0 1.9 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KIK49655.1 - 2e-38 132.5 2.0 3.6e-38 131.7 2.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KIK49655.1 - 1e-22 80.5 0.0 2.9e-22 79.1 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KIK49655.1 - 3.5e-10 40.3 0.0 9.7e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 KIK49655.1 - 0.00014 21.6 0.1 0.00051 19.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIK49655.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KIK49655.1 - 0.12 12.9 0.0 0.44 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Methyltrn_RNA_2 PF04013.12 KIK49656.1 - 0.0092 15.7 0.1 0.018 14.7 0.1 1.5 1 1 0 1 1 1 1 Putative SAM-dependent RNA methyltransferase Septin PF00735.18 KIK49657.1 - 1e-109 366.2 0.2 1.6e-109 365.5 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KIK49657.1 - 3e-07 30.5 0.0 1.1e-06 28.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIK49657.1 - 0.0005 19.7 0.1 0.02 14.4 0.0 2.6 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KIK49657.1 - 0.002 18.2 2.9 0.6 10.2 0.0 3.1 2 1 0 3 3 3 2 Dynamin family AIG1 PF04548.16 KIK49657.1 - 0.0043 16.4 0.0 0.0081 15.5 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KIK49657.1 - 0.018 15.0 4.0 0.06 13.3 0.5 3.1 3 1 0 3 3 3 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 KIK49657.1 - 0.04 13.3 0.1 0.095 12.0 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family MIT PF04212.18 KIK49658.1 - 0.0031 17.5 0.0 0.0078 16.3 0.0 1.7 1 1 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF3543 PF12063.8 KIK49658.1 - 0.037 13.4 0.4 0.061 12.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) Secretin_N_2 PF07655.13 KIK49661.1 - 0.024 15.2 1.5 0.024 15.2 1.5 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain Hydrolase_4 PF12146.8 KIK49662.1 - 1.6e-07 30.8 0.0 5.9e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIK49662.1 - 4e-05 23.4 0.0 8.5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KIK49662.1 - 0.016 15.1 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Aa_trans PF01490.18 KIK49664.1 - 2.7e-36 125.1 36.3 3.2e-36 124.9 36.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2254 PF10011.9 KIK49664.1 - 0.0099 14.7 0.6 0.0099 14.7 0.6 2.6 3 1 1 4 4 4 1 Predicted membrane protein (DUF2254) Acyltransferase PF01553.21 KIK49665.1 - 2.1e-20 72.7 0.0 3.3e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KIK49665.1 - 0.00015 21.8 0.7 0.00041 20.4 0.1 2.0 2 0 0 2 2 2 1 Acyltransferase C-terminus zf-Tim10_DDP PF02953.15 KIK49666.1 - 6.5e-23 80.2 0.1 7.9e-23 79.9 0.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger AlaDh_PNT_N PF05222.15 KIK49669.1 - 6.1e-28 97.8 0.0 9.1e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KIK49669.1 - 0.0081 15.5 0.0 0.016 14.5 0.0 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF5060 PF16586.5 KIK49669.1 - 0.12 12.8 0.0 1.5 9.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5060) adh_short PF00106.25 KIK49670.1 - 8.6e-28 97.1 0.0 1e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK49670.1 - 3.5e-14 52.9 0.0 4.8e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK49670.1 - 3.8e-06 26.9 0.0 1.7e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KIK49670.1 - 0.012 15.9 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain SP24 PF16504.5 KIK49670.1 - 0.052 13.6 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Putative virion membrane protein of plant and insect virus Atrophin-1 PF03154.15 KIK49672.1 - 0.061 11.6 0.2 0.083 11.2 0.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family adh_short PF00106.25 KIK49673.1 - 1e-27 96.9 0.0 1.4e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIK49673.1 - 4.8e-13 49.2 0.0 6.3e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIK49673.1 - 5.3e-06 26.5 0.0 1.9e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KIK49673.1 - 0.012 15.9 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain SP24 PF16504.5 KIK49673.1 - 0.096 12.7 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Putative virion membrane protein of plant and insect virus # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Suillus_luteus_UH-Slu-Lm8-n1-Suilu1/GCA_000827255.1_Suilu1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Suillus_luteus_UH-Slu-Lm8-n1-Suilu1/GCA_000827255.1_Suilu1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Suillus_luteus_UH-Slu-Lm8-n1-Suilu1/GCA_000827255.1_Suilu1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Suillus_luteus_UH-Slu-Lm8-n1-Suilu1/GCA_000827255.1_Suilu1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 07:16:30 2019 # [ok]