# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Spc97_Spc98 PF04130.8 KEY63800.1 - 5.1e-120 401.3 0.5 6.6e-120 400.9 0.3 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family SAGA-Tad1 PF12767.2 KEY63801.1 - 4.6e-53 180.4 0.0 6.6e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit ClpS PF02617.12 KEY63801.1 - 0.2 11.4 0.0 0.46 10.2 0.0 1.5 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS CcmD PF04995.9 KEY63801.1 - 2 8.2 3.5 2 8.1 0.1 2.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) cNMP_binding PF00027.24 KEY63803.1 - 2.7e-41 139.2 0.0 2.8e-23 81.5 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain BCAS2 PF05700.6 KEY63804.1 - 4.6e-43 147.2 0.0 5.1e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF484 PF04340.7 KEY63804.1 - 0.026 14.0 0.3 0.036 13.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF484 TMF_TATA_bd PF12325.3 KEY63804.1 - 0.089 12.5 1.6 0.15 11.8 1.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding HABP4_PAI-RBP1 PF04774.10 KEY63805.1 - 0.0009 19.7 0.1 0.0013 19.2 0.0 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family SH2_2 PF14633.1 KEY63806.1 - 3.3e-77 258.5 1.4 6.1e-77 257.6 0.0 2.1 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 KEY63806.1 - 9e-34 116.0 2.1 9e-34 116.0 1.5 4.3 4 0 0 4 4 4 1 Death-like domain of SPT6 HHH_7 PF14635.1 KEY63806.1 - 3.2e-30 104.3 0.0 7.6e-30 103.1 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 KEY63806.1 - 5.5e-30 103.9 0.0 3e-29 101.5 0.0 2.4 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 KEY63806.1 - 8.2e-25 86.7 30.8 8.2e-25 86.7 21.4 6.1 4 1 1 6 6 6 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 KEY63806.1 - 6.1e-19 68.1 2.7 3e-18 65.9 1.9 2.2 1 1 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 KEY63806.1 - 5e-05 23.0 0.0 0.00013 21.6 0.0 1.8 1 0 0 1 1 1 1 SH2 domain S1 PF00575.18 KEY63806.1 - 0.00018 21.5 0.1 0.00045 20.2 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain HHH_3 PF12836.2 KEY63806.1 - 0.023 14.6 0.0 0.064 13.2 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif B12-binding PF02310.14 KEY63806.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain Pkinase PF00069.20 KEY63807.1 - 8.5e-61 205.3 0.0 1.1e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY63807.1 - 6.7e-39 133.5 0.0 8.6e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY63807.1 - 3.3e-05 22.9 0.0 6.7e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KEY63807.1 - 0.096 11.4 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 HAD_2 PF13419.1 KEY63808.1 - 1.4e-12 48.2 0.0 1e-10 42.1 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEY63808.1 - 1.2e-09 38.9 0.0 1.5e-06 28.7 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEY63808.1 - 2.1e-08 33.7 0.3 3.9e-08 32.8 0.2 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 KEY63808.1 - 1.7e-06 28.3 0.0 2.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 KEY63808.1 - 0.064 12.6 0.0 1 8.6 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase FUSC_2 PF13515.1 KEY63809.1 - 3.1e-23 82.0 7.5 3.1e-23 82.0 5.2 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 KEY63809.1 - 3e-06 25.9 2.0 3e-06 25.9 1.4 2.5 3 0 0 3 3 3 2 Fusaric acid resistance protein family ALMT PF11744.3 KEY63809.1 - 0.00031 19.5 13.2 0.0061 15.2 5.9 3.4 3 1 0 3 3 3 2 Aluminium activated malate transporter FUSC-like PF12805.2 KEY63809.1 - 0.024 13.5 5.9 1.2 8.0 0.3 2.8 2 1 1 3 3 3 0 FUSC-like inner membrane protein yccS DUF2421 PF10334.4 KEY63809.1 - 0.037 13.6 0.0 0.1 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2421) DNA_pol_E_B PF04042.11 KEY63810.1 - 3.9e-62 209.2 0.0 5.6e-62 208.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B HET PF06985.6 KEY63813.1 - 3.1e-24 85.7 0.2 5.3e-24 84.9 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Oxidored_FMN PF00724.15 KEY63814.1 - 8.9e-46 156.4 0.0 1.1e-45 156.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Na_H_Exchanger PF00999.16 KEY63815.1 - 1.4e-34 119.3 19.3 2.4e-34 118.4 13.3 1.3 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 KEY63815.1 - 0.0091 15.9 3.5 0.012 15.4 0.1 3.0 2 0 0 2 2 2 1 YrhC-like protein DUF1097 PF06496.6 KEY63815.1 - 0.027 14.2 13.5 0.37 10.5 2.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1097) Sugar_tr PF00083.19 KEY63816.1 - 1.7e-74 251.0 25.8 2e-74 250.8 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY63816.1 - 2.7e-22 78.9 35.7 1.3e-20 73.4 17.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEY63816.1 - 1.7e-08 33.3 2.7 1.7e-08 33.3 1.9 2.7 2 2 0 2 2 2 1 MFS/sugar transport protein MBOAT PF03062.14 KEY63817.1 - 4.2e-32 111.5 23.3 4e-31 108.3 16.2 2.1 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family HSP90 PF00183.13 KEY63818.1 - 1.3e-256 852.1 31.2 1.6e-256 851.8 21.7 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 KEY63818.1 - 4.6e-12 45.6 0.1 8.6e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KEY63818.1 - 4.3e-11 42.6 0.2 4.3e-11 42.6 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.8 KEY63818.1 - 0.017 15.4 0.8 0.017 15.4 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1676) LOH1CR12 PF10158.4 KEY63818.1 - 0.43 10.3 5.0 0.1 12.4 0.3 2.3 2 0 0 2 2 2 0 Tumour suppressor protein Glyco_hydro_26 PF02156.10 KEY63819.1 - 2.2e-91 306.6 5.2 2.7e-91 306.3 3.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 CBM_6 PF03422.10 KEY63819.1 - 1.3e-05 25.3 0.4 2.4e-05 24.4 0.3 1.4 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) SnoaL_4 PF13577.1 KEY63820.1 - 0.067 13.0 0.1 0.16 11.8 0.0 1.7 2 1 0 2 2 2 0 SnoaL-like domain Vps5 PF09325.5 KEY63821.1 - 2.8e-84 282.0 7.5 2.8e-84 282.0 5.2 1.5 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 KEY63821.1 - 8.3e-23 80.3 0.1 2.4e-22 78.8 0.1 1.9 1 1 0 1 1 1 1 PX domain BAR PF03114.13 KEY63821.1 - 0.0094 15.4 5.8 0.015 14.7 4.0 1.3 1 0 0 1 1 1 1 BAR domain His_Phos_2 PF00328.17 KEY63821.1 - 0.018 14.4 1.7 0.032 13.5 1.2 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) BAR_2 PF10455.4 KEY63821.1 - 0.22 10.3 7.1 0.53 9.1 4.5 1.9 2 1 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking WD40 PF00400.27 KEY63822.1 - 3.8e-46 153.3 14.7 6.2e-08 32.2 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KEY63822.1 - 1.4e-41 141.8 0.1 2.2e-41 141.2 0.1 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit eIF2A PF08662.6 KEY63822.1 - 1.6e-06 28.0 0.0 0.00067 19.4 0.0 3.2 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KEY63822.1 - 9e-05 21.3 0.0 2.3 6.8 0.0 4.0 2 2 0 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 KEY63822.1 - 0.00076 17.7 0.9 1.8 6.6 0.0 3.3 2 1 1 4 4 4 2 Nucleoporin Nup120/160 LisH PF08513.6 KEY63822.1 - 0.004 16.8 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 LisH Nbas_N PF15492.1 KEY63822.1 - 0.075 12.1 0.2 1.9 7.5 0.1 2.7 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Med11 PF10280.4 KEY63823.1 - 1.6e-28 99.0 0.0 2e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein DEC-1_N PF04625.8 KEY63825.1 - 0.091 11.4 0.7 0.11 11.1 0.5 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Ytp1 PF10355.4 KEY63826.1 - 4.2e-83 278.6 13.7 4.2e-83 278.6 9.5 2.0 3 0 0 3 3 3 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KEY63826.1 - 4.4e-30 103.3 2.1 4.4e-30 103.3 1.5 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) DUF897 PF05982.7 KEY63826.1 - 0.011 14.5 1.4 0.011 14.5 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF897) Borrelia_P13 PF05628.7 KEY63826.1 - 0.16 11.7 5.4 5.2 6.8 0.1 3.2 3 0 0 3 3 3 0 Borrelia membrane protein P13 zf-IS66 PF13005.2 KEY63828.1 - 0.041 13.8 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 zinc-finger binding domain of transposase IS66 Clp1 PF06807.9 KEY63828.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 MPC PF03650.8 KEY63833.1 - 4e-34 117.1 0.1 5e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) OGG_N PF07934.7 KEY63834.1 - 2.2e-35 121.1 0.1 4.1e-35 120.2 0.1 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 KEY63834.1 - 5.3e-17 62.0 0.0 1e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KEY63834.1 - 0.00013 21.5 0.0 0.00035 20.0 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif RRM_1 PF00076.17 KEY63835.1 - 1.7e-28 98.0 0.8 2.9e-10 39.6 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY63835.1 - 4.7e-20 71.3 0.1 3.6e-06 26.8 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY63835.1 - 1.4e-14 53.6 0.0 6.1e-08 32.4 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEY63835.1 - 0.18 11.6 0.0 11 5.8 0.0 2.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Ribosomal_S13_N PF08069.7 KEY63836.1 - 8e-28 96.0 0.1 1.9e-27 94.8 0.1 1.7 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 KEY63836.1 - 1.2e-15 57.0 0.1 3.1e-13 49.2 0.1 2.4 2 0 0 2 2 2 2 Ribosomal protein S15 PAX PF00292.13 KEY63836.1 - 0.041 13.5 0.1 0.096 12.3 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain DUF3860 PF12976.2 KEY63836.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) Dpy-30 PF05186.8 KEY63837.1 - 4.9e-13 48.3 0.0 6.6e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif DUF605 PF04652.11 KEY63837.1 - 4.6 6.5 11.2 5 6.4 7.8 1.1 1 0 0 1 1 1 0 Vta1 like VRR_NUC PF08774.6 KEY63838.1 - 4.5e-16 58.7 0.0 1.1e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain p450 PF00067.17 KEY63839.1 - 1.5e-67 228.1 0.0 1.9e-67 227.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 KEY63840.1 - 6.4e-41 140.1 0.0 8e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KEY63840.1 - 2.6e-05 24.7 0.0 8.4e-05 23.1 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY63840.1 - 0.00032 21.1 0.0 0.00081 19.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY63840.1 - 0.0013 18.4 0.0 0.0037 17.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain DUF4423 PF14394.1 KEY63840.1 - 0.0038 16.8 0.0 0.0067 15.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) Methyltransf_4 PF02390.12 KEY63840.1 - 0.032 13.2 0.0 0.058 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase CheR PF01739.13 KEY63840.1 - 0.11 11.7 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain FAD_binding_3 PF01494.14 KEY63841.1 - 3.3e-18 65.8 0.1 1.1e-08 34.5 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KEY63841.1 - 6.6e-07 28.5 0.7 6.1e-06 25.3 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY63841.1 - 1.6e-05 24.8 0.2 4e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KEY63841.1 - 0.0077 15.3 0.1 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KEY63841.1 - 0.015 15.6 0.0 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEY63841.1 - 0.037 12.8 0.2 0.063 12.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain GST_N_3 PF13417.1 KEY63842.1 - 2.7e-10 40.3 0.0 5.7e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEY63842.1 - 7.5e-10 38.6 0.0 1.3e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KEY63842.1 - 2e-07 30.8 0.1 4.9e-07 29.6 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KEY63842.1 - 3e-07 30.5 0.0 7.2e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEY63842.1 - 8.9e-05 22.3 0.1 0.00025 20.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEY63842.1 - 0.013 15.9 0.0 0.034 14.6 0.0 1.8 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain Tri3 PF07428.6 KEY63843.1 - 0.024 13.3 0.0 0.063 11.9 0.0 1.6 2 0 0 2 2 2 0 15-O-acetyltransferase Tri3 AATase PF07247.7 KEY63843.1 - 0.14 10.6 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Alcohol acetyltransferase Zn_clus PF00172.13 KEY63845.1 - 2.4e-10 40.1 6.8 2.4e-10 40.1 4.7 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.5 KEY63845.1 - 4.5e-05 22.6 0.1 8.2e-05 21.7 0.1 1.4 1 0 0 1 1 1 1 Aflatoxin regulatory protein DUF2797 PF10977.3 KEY63845.1 - 0.54 9.8 3.2 1.9 8.0 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2797) Epimerase PF01370.16 KEY63846.1 - 5.3e-09 35.8 0.0 7.8e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY63846.1 - 0.0011 19.0 0.1 0.028 14.4 0.0 2.6 2 1 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 KEY63847.1 - 5.8e-10 39.3 0.5 8.1e-10 38.8 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY63847.1 - 1.1e-06 28.4 0.6 1.7e-06 27.8 0.4 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KEY63847.1 - 6.3e-06 26.3 1.7 1.2e-05 25.4 1.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 KEY63847.1 - 7.6e-06 25.8 0.0 6.9e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 KEY63847.1 - 0.0001 21.6 2.9 0.00025 20.3 2.0 1.9 1 1 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.12 KEY63847.1 - 0.00059 20.2 0.5 0.008 16.5 0.1 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 KEY63847.1 - 0.001 18.5 0.3 0.0016 17.9 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KEY63847.1 - 0.012 15.3 0.1 0.041 13.6 0.1 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N PF00107.21 KEY63847.1 - 0.017 14.6 0.2 0.032 13.7 0.2 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.19 KEY63847.1 - 0.078 13.2 0.2 0.17 12.1 0.2 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KEY63847.1 - 0.084 12.7 1.3 0.18 11.7 0.9 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus SnoaL_2 PF12680.2 KEY63847.1 - 0.085 13.2 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain MOSC PF03473.12 KEY63848.1 - 2.2e-19 69.2 0.0 4.5e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.22 KEY63848.1 - 7.3e-10 38.4 1.3 1.6e-09 37.3 0.9 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.16 KEY63848.1 - 6.9e-09 36.2 0.0 2e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KEY63848.1 - 0.0019 18.0 0.5 0.23 11.3 0.1 2.5 1 1 0 2 2 2 2 Ferric reductase NAD binding domain 3-alpha PF03475.9 KEY63848.1 - 0.0028 17.3 0.2 0.0062 16.2 0.1 1.6 1 0 0 1 1 1 1 3-alpha domain RRP7 PF12923.2 KEY63849.1 - 8.6e-35 119.6 13.6 1.6e-34 118.7 9.4 1.4 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) DUF960 PF06124.6 KEY63849.1 - 0.029 14.5 0.1 0.068 13.4 0.1 1.6 1 0 0 1 1 1 0 Staphylococcal protein of unknown function (DUF960) CCDC50_N PF15295.1 KEY63849.1 - 4.2 7.3 12.6 6.6 6.6 3.9 2.7 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 50 N-terminus DUF92 PF01940.11 KEY63850.1 - 1e-53 181.8 1.0 7.1e-52 175.7 0.7 2.3 1 1 0 1 1 1 1 Integral membrane protein DUF92 ADIP PF11559.3 KEY63850.1 - 6.9e-32 110.4 3.4 6.9e-32 110.4 2.3 3.1 4 0 0 4 4 4 1 Afadin- and alpha -actinin-Binding DUF641 PF04859.7 KEY63850.1 - 0.26 11.0 6.7 6.5 6.5 2.9 2.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.3 KEY63850.1 - 0.86 9.4 16.7 0.14 11.9 2.5 3.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.6 KEY63850.1 - 0.97 8.0 7.8 0.16 10.5 2.5 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein EHN PF06441.7 KEY63851.1 - 3.6e-22 78.3 0.2 1e-21 76.9 0.1 1.8 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KEY63851.1 - 8.9e-15 55.1 0.3 1.9e-14 54.1 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family WSC PF01822.14 KEY63851.1 - 4.9e-14 52.0 7.0 1.2e-13 50.8 4.8 1.7 1 0 0 1 1 1 1 WSC domain Abhydrolase_5 PF12695.2 KEY63851.1 - 8.9e-05 22.2 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY63851.1 - 0.03 13.8 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DDE_Tnp_1_7 PF13843.1 KEY63853.1 - 0.005 15.9 0.0 0.0064 15.5 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 CHAT PF12770.2 KEY63854.1 - 1.8e-27 96.2 0.0 1.1e-26 93.7 0.0 2.0 2 0 0 2 2 2 1 CHAT domain Peptidase_C14 PF00656.17 KEY63855.1 - 2.2e-18 66.8 0.0 5.6e-18 65.5 0.0 1.6 1 1 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KEY63855.1 - 0.032 14.0 0.4 0.38 10.6 0.3 2.1 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain p450 PF00067.17 KEY63856.1 - 4.2e-38 131.0 0.0 9.9e-31 106.7 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Zn_clus PF00172.13 KEY63857.1 - 0.05 13.5 7.6 0.094 12.6 5.2 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SnoaL_4 PF13577.1 KEY63858.1 - 5.1e-15 55.5 0.0 5.8e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain Pectate_lyase_3 PF12708.2 KEY63859.1 - 6.3e-59 199.8 16.1 1.8e-51 175.4 3.7 3.7 3 1 0 3 3 3 2 Pectate lyase superfamily protein HRXXH PF13933.1 KEY63861.1 - 0.039 13.3 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family FAD_binding_3 PF01494.14 KEY63863.1 - 4.7e-22 78.5 2.0 8.7e-17 61.2 0.8 3.0 1 1 1 2 2 2 2 FAD binding domain Amino_oxidase PF01593.19 KEY63863.1 - 4.8e-07 29.2 8.9 0.00054 19.1 0.1 3.0 4 0 0 4 4 4 2 Flavin containing amine oxidoreductase DAO PF01266.19 KEY63863.1 - 0.00012 21.0 0.0 0.06 12.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEY63863.1 - 0.00015 20.8 0.4 0.0012 17.8 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KEY63863.1 - 0.026 14.5 0.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEY63863.1 - 0.032 14.3 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.21 KEY63865.1 - 3.1e-19 68.8 0.0 4.9e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY63865.1 - 4.2e-06 27.6 0.0 7.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.1 KEY63866.1 - 4.8e-28 98.5 0.0 5.7e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEY63866.1 - 1e-25 90.5 1.1 1.8e-25 89.7 0.8 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY63866.1 - 1e-09 38.3 0.4 1.5e-09 37.7 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY63866.1 - 0.0057 16.1 0.4 0.029 13.7 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HHH_5 PF14520.1 KEY63866.1 - 0.19 11.9 1.0 0.95 9.6 0.1 2.3 2 1 0 2 2 2 0 Helix-hairpin-helix domain ABC_membrane PF00664.18 KEY63867.1 - 5e-69 232.7 38.2 2.8e-41 141.7 11.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KEY63867.1 - 3.8e-60 202.1 0.1 4.8e-33 114.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KEY63867.1 - 1.5e-12 47.2 0.0 2.2e-06 27.0 0.0 3.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 KEY63867.1 - 4.2e-09 35.4 0.0 0.0035 16.0 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_21 PF13304.1 KEY63867.1 - 1.2e-08 35.2 3.0 0.038 13.9 0.2 4.4 4 1 0 4 4 3 3 AAA domain AAA_16 PF13191.1 KEY63867.1 - 6.1e-07 29.6 1.3 0.00029 20.8 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KEY63867.1 - 1.8e-05 24.2 2.1 0.069 12.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KEY63867.1 - 1.9e-05 24.7 0.5 0.49 10.5 0.0 4.0 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 KEY63867.1 - 2.1e-05 23.7 0.1 0.03 13.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KEY63867.1 - 3.9e-05 24.4 0.0 0.17 12.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KEY63867.1 - 0.00032 20.5 1.0 1.5 8.8 0.1 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 KEY63867.1 - 0.0018 17.3 1.1 2 7.4 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin AAA_30 PF13604.1 KEY63867.1 - 0.0043 16.6 1.5 0.9 9.0 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 KEY63867.1 - 0.017 15.3 0.1 9.1 6.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.1 KEY63867.1 - 0.028 13.7 0.1 0.2 11.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 KEY63867.1 - 0.03 14.2 0.4 0.75 9.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA PF00004.24 KEY63867.1 - 0.037 14.2 2.9 8 6.6 0.0 4.2 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEY63867.1 - 0.039 13.6 0.2 11 5.7 0.0 3.6 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KEY63867.1 - 0.1 12.5 0.2 0.58 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 KEY63867.1 - 0.16 10.9 0.0 5.3 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 KEY63867.1 - 0.29 11.4 0.6 7.5 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 KEY63867.1 - 0.3 9.7 0.0 12 4.4 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Fungal_trans PF04082.13 KEY63868.1 - 5e-15 55.0 0.2 1.7e-14 53.3 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Gti1_Pac2 PF09729.4 KEY63871.1 - 5e-34 117.6 0.1 9.9e-29 100.3 0.0 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Pkinase PF00069.20 KEY63873.1 - 3.7e-08 32.8 0.0 5.4e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KEY63873.1 - 2e-05 24.4 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KEY63873.1 - 0.0019 17.3 0.0 0.0028 16.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KEY63873.1 - 0.0028 16.7 0.1 0.011 14.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase DUF2650 PF10853.3 KEY63873.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) YrbL-PhoP_reg PF10707.4 KEY63873.1 - 0.02 14.2 0.0 0.035 13.4 0.0 1.3 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 KEY63873.1 - 0.11 12.0 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 KEY63873.1 - 0.12 11.1 0.2 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase EcKinase PF02958.15 KEY63873.1 - 0.19 10.8 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase KR PF08659.5 KEY63875.1 - 5.8e-40 136.8 6.2 9e-38 129.7 4.3 3.0 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 KEY63875.1 - 1.4e-26 93.3 11.8 3.9e-26 91.9 3.0 3.3 3 1 0 3 3 3 1 short chain dehydrogenase Acyl_transf_1 PF00698.16 KEY63875.1 - 9.1e-24 84.3 0.0 1.9e-17 63.6 0.0 2.6 2 0 0 2 2 2 2 Acyl transferase domain ADH_zinc_N PF00107.21 KEY63875.1 - 1.2e-16 60.4 0.8 2.8e-16 59.2 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY63875.1 - 3e-09 37.8 0.1 1.9e-08 35.2 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 KEY63875.1 - 1.4e-07 31.6 0.0 3.4e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 KEY63875.1 - 3.7e-05 23.4 0.1 7.9e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain IU_nuc_hydro PF01156.14 KEY63876.1 - 8.4e-15 54.7 0.0 9.7e-15 54.5 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Transferase PF02458.10 KEY63877.1 - 1.1e-09 37.2 0.0 7.3e-08 31.2 0.0 2.6 2 1 0 2 2 2 2 Transferase family SGL PF08450.7 KEY63878.1 - 5.4e-67 225.7 0.0 7.1e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KEY63878.1 - 1.7e-05 24.6 0.0 4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Arylesterase DUF4248 PF14053.1 KEY63879.1 - 0.055 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) NAD_binding_10 PF13460.1 KEY63880.1 - 1e-07 32.1 0.7 3.6e-07 30.3 0.5 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEY63880.1 - 2e-07 30.7 0.0 3.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEY63880.1 - 3.1e-05 22.8 0.0 4.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KEY63880.1 - 3.8e-05 23.0 0.0 0.00024 20.4 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.7 KEY63880.1 - 0.00018 20.5 0.0 0.0059 15.5 0.0 2.6 1 1 0 1 1 1 1 Male sterility protein Fungal_trans_2 PF11951.3 KEY63880.1 - 0.0018 16.9 0.1 0.0027 16.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 KEY63880.1 - 0.0022 17.9 3.4 0.0046 16.8 0.5 2.8 3 1 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 KEY63880.1 - 0.008 15.8 0.5 13 5.4 0.0 3.5 3 0 0 3 3 3 1 KR domain RmlD_sub_bind PF04321.12 KEY63880.1 - 0.054 12.3 0.0 0.14 11.0 0.0 1.6 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KEY63880.1 - 0.12 11.2 0.1 0.32 9.8 0.1 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Lactamase_B PF00753.22 KEY63882.1 - 6.7e-23 81.3 2.9 7.7e-22 77.8 2.0 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KEY63882.1 - 3.2e-06 26.8 1.1 6.3e-06 25.8 0.8 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KEY63882.1 - 0.00053 19.7 0.0 0.00082 19.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain ketoacyl-synt PF00109.21 KEY63883.1 - 1.3e-70 237.7 0.1 2.6e-70 236.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEY63883.1 - 2.2e-52 178.4 0.1 8.4e-52 176.4 0.0 2.0 3 0 0 3 3 3 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KEY63883.1 - 1.8e-33 114.8 0.6 5.3e-33 113.3 0.2 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KEY63883.1 - 1.7e-07 31.4 0.5 4.9e-07 29.9 0.4 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 KEY63883.1 - 2.8e-05 23.9 0.2 9.9e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 KEY63883.1 - 0.00011 21.2 0.0 0.00035 19.6 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Myb_DNA-bind_6 PF13921.1 KEY63884.1 - 0.00013 21.9 0.2 0.0003 20.8 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KEY63884.1 - 0.00058 19.8 0.1 0.0013 18.7 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Chromo PF00385.19 KEY63885.1 - 9.7e-06 25.1 0.6 1.4e-05 24.6 0.0 1.5 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2841 PF11001.3 KEY63886.1 - 1.7e-35 121.6 4.2 3.1e-35 120.7 2.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) MSP7_C PF12948.2 KEY63886.1 - 0.08 13.1 0.4 0.17 12.1 0.2 1.4 1 0 0 1 1 1 0 MSP7-like protein C-terminal domain Tyrosinase PF00264.15 KEY63887.1 - 2e-44 152.4 0.2 2.7e-44 151.9 0.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase MFS_2 PF13347.1 KEY63888.1 - 1.2e-07 30.5 7.7 1.2e-07 30.5 5.3 2.6 3 0 0 3 3 3 1 MFS/sugar transport protein Bundlin PF05307.6 KEY63888.1 - 0.11 12.3 0.4 0.29 11.0 0.3 1.7 1 0 0 1 1 1 0 Bundlin TAF1D PF15333.1 KEY63889.1 - 0.097 12.4 2.6 0.13 12.0 1.8 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D DUF566 PF04484.7 KEY63889.1 - 0.17 11.3 8.5 0.19 11.2 5.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Myb_DNA-bind_6 PF13921.1 KEY63890.1 - 2.7e-10 40.1 0.0 0.00013 21.9 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KEY63890.1 - 0.00024 21.0 2.7 0.091 12.8 1.1 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain HET PF06985.6 KEY63891.1 - 1.2e-23 83.7 0.0 2.5e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) tRNA-synt_2c PF01411.14 KEY63891.1 - 0.051 11.8 0.0 0.15 10.2 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class II (A) HSDR_N_2 PF13588.1 KEY63893.1 - 0.032 14.0 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Las1 PF04031.8 KEY63895.1 - 2.6e-60 202.5 1.4 4e-60 201.9 1.0 1.3 1 0 0 1 1 1 1 Las1-like Med3 PF11593.3 KEY63895.1 - 0.029 13.6 1.4 0.036 13.3 0.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Lactamase_B PF00753.22 KEY63896.1 - 1.9e-13 50.5 0.2 3.2e-13 49.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily EF-hand_7 PF13499.1 KEY63896.1 - 0.0014 18.6 0.0 0.019 15.1 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KEY63896.1 - 0.0019 17.9 0.1 32 4.7 0.0 4.4 4 0 0 4 4 4 0 EF-hand domain BcrAD_BadFG PF01869.15 KEY63896.1 - 0.0071 15.6 0.0 0.016 14.5 0.0 1.6 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family EF-hand_1 PF00036.27 KEY63896.1 - 0.095 12.0 1.1 1.7 8.1 0.0 3.4 4 0 0 4 4 4 0 EF hand bZIP_1 PF00170.16 KEY63899.1 - 0.0015 18.4 12.2 0.0038 17.1 8.5 1.6 1 1 0 1 1 1 1 bZIP transcription factor WD40_alt PF14077.1 KEY63899.1 - 0.032 13.8 0.6 0.032 13.8 0.4 1.7 2 0 0 2 2 2 0 Alternative WD40 repeat motif DivIC PF04977.10 KEY63899.1 - 0.29 10.6 7.2 0.62 9.5 1.6 2.3 1 1 1 2 2 2 0 Septum formation initiator bZIP_2 PF07716.10 KEY63899.1 - 1.5 8.7 16.1 2.6 7.9 5.0 2.3 1 1 1 2 2 2 0 Basic region leucine zipper DUF904 PF06005.7 KEY63899.1 - 5.8 7.2 11.0 19 5.6 7.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF904) FAD_binding_4 PF01565.18 KEY63900.1 - 5.2e-16 58.3 0.9 1.2e-15 57.2 0.6 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY63900.1 - 2.2e-09 37.0 0.0 5.6e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Chromo PF00385.19 KEY63902.1 - 5.1e-09 35.6 0.1 1.2e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mo-co_dimer PF03404.11 KEY63903.1 - 0.033 13.8 0.2 0.055 13.1 0.1 1.4 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Metallophos_2 PF12850.2 KEY63905.1 - 1.9e-08 34.2 0.0 4.4e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KEY63905.1 - 6.9e-07 28.8 2.7 1.3e-05 24.6 1.9 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase MutL PF13941.1 KEY63905.1 - 0.034 12.4 0.0 0.048 11.9 0.0 1.1 1 0 0 1 1 1 0 MutL protein Fungal_trans PF04082.13 KEY63907.1 - 5.1e-17 61.5 0.2 8.9e-17 60.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY63907.1 - 2.4e-05 24.1 16.9 4.3e-05 23.3 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 KEY63907.1 - 1.6 8.0 19.0 2.5 7.3 13.1 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 KEY63907.1 - 8.4 4.4 25.1 13 3.8 17.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NAD_binding_10 PF13460.1 KEY63908.1 - 2.6e-21 76.4 0.0 3e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEY63908.1 - 6.4e-05 22.5 0.0 8.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KEY63908.1 - 0.0012 18.1 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family MIP PF00230.15 KEY63909.1 - 4.1e-40 137.6 12.7 4.7e-40 137.4 8.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein ADH_N PF08240.7 KEY63910.1 - 9.4e-29 99.3 0.7 1.9e-28 98.3 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY63910.1 - 2.4e-11 43.2 0.1 3.6e-09 36.2 0.1 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KEY63910.1 - 5e-07 29.2 1.3 5e-07 29.2 0.9 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Methyltransf_18 PF12847.2 KEY63910.1 - 0.0018 18.8 0.0 0.0047 17.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain NADH_4Fe-4S PF10589.4 KEY63910.1 - 0.011 14.8 2.0 0.04 13.0 1.3 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Met_10 PF02475.11 KEY63910.1 - 0.026 14.1 0.0 0.053 13.1 0.0 1.6 1 0 0 1 1 1 0 Met-10+ like-protein FANCL_C PF11793.3 KEY63910.1 - 0.053 13.4 0.3 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain AlaDh_PNT_C PF01262.16 KEY63910.1 - 0.058 12.9 0.3 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 KEY63910.1 - 0.06 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CTP_transf_2 PF01467.21 KEY63911.1 - 4.4e-26 91.8 0.0 7.6e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase DUF2461 PF09365.5 KEY63913.1 - 3.3e-53 180.2 0.1 4.3e-53 179.8 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) AT_hook PF02178.14 KEY63913.1 - 0.026 14.1 3.9 0.12 12.1 2.7 2.3 1 0 0 1 1 1 0 AT hook motif HMG14_17 PF01101.13 KEY63913.1 - 0.54 10.9 9.1 0.49 11.1 4.7 2.1 2 0 0 2 2 2 0 HMG14 and HMG17 TFIIA PF03153.8 KEY63913.1 - 0.85 9.4 10.7 1.2 8.9 7.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.7 KEY63913.1 - 0.87 8.7 4.6 1.3 8.2 3.2 1.2 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.9 KEY63913.1 - 1 8.8 4.6 1.5 8.3 3.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Cwf_Cwc_15 PF04889.7 KEY63913.1 - 4.7 6.8 9.7 7.5 6.1 6.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Fungal_trans PF04082.13 KEY63914.1 - 8.5e-18 64.1 1.3 8.5e-18 64.1 0.9 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain p450 PF00067.17 KEY63915.1 - 3.9e-39 134.4 0.0 5e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DEAD PF00270.24 KEY63916.1 - 1.1e-42 145.4 0.0 1.5e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY63916.1 - 5.6e-24 83.8 0.1 5.6e-24 83.8 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 KEY63916.1 - 0.1 11.6 0.0 0.23 10.4 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit adh_short PF00106.20 KEY63917.1 - 4e-29 101.6 0.0 5.8e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY63917.1 - 4.9e-29 101.7 0.0 6e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY63917.1 - 2.3e-10 40.4 0.0 3.3e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KEY63917.1 - 0.00024 20.8 1.5 0.00063 19.4 0.7 1.9 1 1 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KEY63917.1 - 0.0064 15.5 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.5 KEY63917.1 - 0.04 13.0 0.0 0.059 12.5 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Aldo_ket_red PF00248.16 KEY63919.1 - 0.0006 18.7 0.0 0.0006 18.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3425 PF11905.3 KEY63920.1 - 1.8e-28 99.1 2.3 3.9e-28 98.0 1.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) DUF3435 PF11917.3 KEY63921.1 - 6.2e-49 166.8 0.9 6.9e-44 150.2 0.7 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF3435) Abhydrolase_6 PF12697.2 KEY63922.1 - 2e-29 103.1 4.9 2.6e-29 102.7 3.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY63922.1 - 1.4e-12 47.5 0.0 2.9e-12 46.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY63922.1 - 1.7e-10 40.8 0.2 9.1e-10 38.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 KEY63922.1 - 2.9e-07 29.2 0.0 3.9e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 KEY63922.1 - 0.0008 19.2 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Methyltransf_23 PF13489.1 KEY63923.1 - 3.8e-15 55.9 0.0 6e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY63923.1 - 1.2e-10 41.6 0.0 2.5e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY63923.1 - 4.6e-09 36.8 0.0 3.1e-08 34.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY63923.1 - 1e-07 32.3 0.0 1.8e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY63923.1 - 6.9e-07 28.9 0.0 4.9e-06 26.2 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY63923.1 - 8.2e-07 29.3 0.0 2.1e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEY63923.1 - 0.00066 18.7 0.0 0.0016 17.5 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 KEY63923.1 - 0.00081 19.4 0.1 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY63923.1 - 0.002 17.5 0.0 0.0068 15.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KEY63923.1 - 0.014 14.5 0.0 0.17 10.9 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 KEY63923.1 - 0.017 15.1 0.0 0.039 13.9 0.0 1.5 2 0 0 2 2 2 0 FtsJ-like methyltransferase DUF938 PF06080.7 KEY63923.1 - 0.039 13.4 0.0 0.094 12.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Gln-synt_C PF00120.19 KEY63924.1 - 8.3e-60 202.1 0.0 1.1e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain adh_short PF00106.20 KEY63926.1 - 1.5e-13 50.9 0.2 3.2e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY63926.1 - 6.3e-07 29.2 0.4 1.2e-06 28.3 0.3 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KEY63926.1 - 0.00011 21.2 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 KEY63926.1 - 0.0012 18.6 0.0 0.0025 17.6 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 KEY63926.1 - 0.012 15.7 0.1 0.021 14.8 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ecl1 PF12855.2 KEY63928.1 - 8.8e-12 44.1 2.1 1.4e-11 43.4 1.5 1.3 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 KEY63928.1 - 0.14 12.0 1.7 0.29 11.0 1.1 1.5 1 0 0 1 1 1 0 MYND finger Pec_lyase_C PF00544.14 KEY63929.1 - 1.8e-19 70.0 2.8 3.8e-19 68.9 1.9 1.5 1 1 0 1 1 1 1 Pectate lyase CBM_1 PF00734.13 KEY63929.1 - 1.4e-09 37.4 11.8 3.3e-09 36.2 8.2 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KEY63929.1 - 0.13 12.3 2.7 0.27 11.3 1.8 1.6 1 0 0 1 1 1 0 Toxin 7 4HBT_3 PF13622.1 KEY63931.1 - 6.3e-34 117.8 0.1 8.5e-34 117.4 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Dimer_Tnp_hAT PF05699.9 KEY63934.1 - 1.9e-05 24.1 0.3 5.5e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 KEY63934.1 - 0.044 13.5 0.8 0.14 11.9 0.6 2.0 1 0 0 1 1 1 0 BED zinc finger HET PF06985.6 KEY63935.1 - 4.8e-24 85.0 0.0 9.6e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.18 KEY63936.1 - 1e-18 67.1 5.1 3.7e-18 65.3 3.5 1.8 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY63936.1 - 2.1e-07 30.7 0.0 4.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like PAP2 PF01569.16 KEY63937.1 - 1.9e-21 76.0 1.8 1.9e-21 76.0 1.2 2.1 2 0 0 2 2 2 1 PAP2 superfamily PRA1 PF03208.14 KEY63937.1 - 0.021 14.1 1.4 0.07 12.4 1.0 1.9 1 0 0 1 1 1 0 PRA1 family protein RDD PF06271.7 KEY63937.1 - 0.25 11.2 8.2 0.63 9.9 0.6 2.8 2 1 1 3 3 3 0 RDD family APH PF01636.18 KEY63939.1 - 3.4e-14 53.1 0.0 5.9e-14 52.3 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEY63939.1 - 1.9e-05 24.3 0.0 5.8e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.20 KEY63939.1 - 0.052 12.6 0.0 1.8 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain DUF1885 PF08968.5 KEY63940.1 - 0.07 12.7 0.0 0.08 12.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1885) Peptidase_M28 PF04389.12 KEY63941.1 - 2.9e-35 121.6 0.2 4.9e-35 120.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KEY63941.1 - 3.2e-05 23.5 0.1 6.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 LCM PF04072.9 KEY63942.1 - 1.8e-32 112.4 0.0 2.3e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Tymo_coat PF00983.13 KEY63943.1 - 0.037 13.7 0.1 0.058 13.1 0.1 1.2 1 0 0 1 1 1 0 Tymovirus coat protein KR PF08659.5 KEY63945.1 - 4.7e-25 88.3 0.0 1.1e-24 87.1 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KEY63945.1 - 7.9e-17 61.6 0.1 4e-16 59.3 0.0 2.1 3 0 0 3 3 3 1 short chain dehydrogenase PP-binding PF00550.20 KEY63945.1 - 1.9e-08 34.4 0.0 3.9e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site YesK PF14150.1 KEY63947.1 - 0.17 11.9 0.6 0.68 10.0 0.0 2.0 2 0 0 2 2 2 0 YesK-like protein Pkinase PF00069.20 KEY63949.1 - 1.3e-05 24.4 0.0 1.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KEY63949.1 - 0.00058 19.6 0.1 0.002 17.8 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KEY63949.1 - 0.0073 15.3 0.1 0.022 13.7 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KEY63949.1 - 0.052 13.1 0.0 0.12 11.9 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.17 KEY63949.1 - 0.074 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DDE_Tnp_1_7 PF13843.1 KEY63951.1 - 0.00053 19.1 0.0 0.00055 19.0 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 Cut8_N PF14482.1 KEY63951.1 - 0.019 14.9 0.1 0.019 14.9 0.1 1.8 1 1 1 2 2 2 0 Cut8 proteasome-binding domain Suf PF05843.9 KEY63951.1 - 0.071 12.8 0.2 0.08 12.6 0.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4175 PF13779.1 KEY63951.1 - 9.7 3.7 10.1 12 3.4 7.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) MitoNEET_N PF10660.4 KEY63952.1 - 0.072 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus NAD_binding_10 PF13460.1 KEY63954.1 - 4.1e-15 56.2 0.0 1.3e-14 54.5 0.0 1.8 2 1 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KEY63954.1 - 4.6e-15 55.4 0.0 6e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KEY63954.1 - 2.5e-05 23.8 0.4 0.065 12.6 0.0 3.1 3 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KEY63954.1 - 0.079 11.8 0.0 1.5 7.6 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain PAF-AH_p_II PF03403.8 KEY63956.1 - 8e-44 149.4 0.0 2.1e-42 144.7 0.0 2.2 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KEY63956.1 - 2.5e-10 40.2 0.0 6.2e-10 39.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY63956.1 - 2.7e-05 24.1 0.1 7.5e-05 22.7 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KEY63956.1 - 0.005 15.7 0.0 0.018 13.9 0.0 1.9 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KEY63956.1 - 0.015 14.0 0.0 0.032 13.0 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase GMC_oxred_C PF05199.8 KEY63957.1 - 1.6e-08 34.9 0.0 2.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KEY63957.1 - 2.7e-08 33.3 0.2 4.2e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase zf-C3HC4 PF00097.20 KEY63958.1 - 0.0078 15.8 6.9 0.0078 15.8 4.8 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEY63958.1 - 0.0081 15.9 5.1 0.0081 15.9 3.5 2.8 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 KEY63958.1 - 0.061 13.2 0.3 0.061 13.2 0.2 3.1 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KEY63958.1 - 4 7.2 14.1 0.22 11.2 2.0 3.2 2 2 0 2 2 2 0 RING-type zinc-finger Nop14 PF04147.7 KEY63959.1 - 0.00076 17.5 2.1 0.00082 17.4 1.4 1.1 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 KEY63959.1 - 0.0051 15.3 3.6 0.0062 15.0 2.5 1.1 1 0 0 1 1 1 1 Daxx Family CDC45 PF02724.9 KEY63959.1 - 0.016 13.2 2.6 0.02 12.9 1.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 KEY63959.1 - 0.022 14.3 6.9 0.038 13.4 4.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin Amnionless PF14828.1 KEY63959.1 - 0.026 13.0 0.0 0.04 12.4 0.0 1.2 1 0 0 1 1 1 0 Amnionless BUD22 PF09073.5 KEY63959.1 - 0.054 12.5 5.8 0.068 12.2 4.0 1.1 1 0 0 1 1 1 0 BUD22 DUF1183 PF06682.7 KEY63959.1 - 0.067 12.7 0.4 0.095 12.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Podoplanin PF05808.6 KEY63959.1 - 0.071 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Podoplanin eIF-3c_N PF05470.7 KEY63959.1 - 0.13 10.2 0.6 0.17 9.9 0.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SDA1 PF05285.7 KEY63959.1 - 0.26 10.5 6.3 0.36 10.0 4.4 1.3 1 0 0 1 1 1 0 SDA1 VSP PF03302.8 KEY63959.1 - 1.1 7.8 3.5 1.8 7.0 2.4 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein SpoVR PF04293.8 KEY63961.1 - 0.04 12.2 0.1 0.047 12.0 0.1 1.1 1 0 0 1 1 1 0 SpoVR like protein Voldacs PF03517.8 KEY63962.1 - 1.4e-25 89.7 0.0 2.9e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling BSP_II PF05432.6 KEY63963.1 - 0.0015 17.8 11.3 0.0033 16.7 7.9 1.5 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) CDC45 PF02724.9 KEY63963.1 - 0.67 7.9 9.7 1.2 7.0 6.7 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF1996 PF09362.5 KEY63964.1 - 2.7e-73 246.5 0.1 3.5e-73 246.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TPR_11 PF13414.1 KEY63965.1 - 4.6e-09 35.8 0.0 5.2e-08 32.4 0.0 2.6 3 0 0 3 3 3 1 TPR repeat UBA PF00627.26 KEY63965.1 - 7.8e-07 28.7 0.1 1.8e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain TPR_2 PF07719.12 KEY63965.1 - 0.0011 18.7 0.0 16 5.7 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEY63965.1 - 0.0013 18.2 0.0 2 8.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEY63965.1 - 0.0018 18.1 1.9 0.01 15.7 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DnaJ PF00226.26 KEY63965.1 - 0.033 13.9 0.0 0.084 12.6 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain UQ_con PF00179.21 KEY63966.1 - 4.4e-45 152.5 0.0 1.5e-24 86.0 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Formyl_trans_N PF00551.14 KEY63967.1 - 5.1e-31 107.6 0.0 6.1e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase DUF2336 PF10098.4 KEY63967.1 - 0.063 12.5 0.1 0.095 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2336) Barstar PF01337.13 KEY63967.1 - 0.1 12.4 0.0 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 Barstar (barnase inhibitor) tRNA-synt_1e PF01406.14 KEY63968.1 - 1.3e-112 375.8 0.0 2.2e-112 375.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KEY63968.1 - 6.9e-06 24.9 0.2 0.092 11.3 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KEY63968.1 - 0.03 12.3 0.0 0.5 8.2 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (I, L, M and V) GCD14 PF08704.5 KEY63969.1 - 1.1e-64 218.3 2.5 6.5e-63 212.4 0.1 3.4 2 1 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 KEY63969.1 - 0.00054 20.5 0.0 0.0075 16.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY63969.1 - 0.0017 18.4 0.0 0.027 14.5 0.0 2.5 1 1 0 2 2 2 1 Methyltransferase domain LSM PF01423.17 KEY63970.1 - 4.5e-15 54.9 0.2 6.3e-15 54.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain EMP24_GP25L PF01105.19 KEY63972.1 - 0.75 9.4 3.8 3.1 7.4 0.3 2.5 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF1993 PF09351.5 KEY63972.1 - 1.6 8.6 7.5 1.3 8.8 0.4 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF1993) p450 PF00067.17 KEY63973.1 - 1.9e-75 254.1 0.0 2.4e-75 253.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_18 PF00704.23 KEY63974.1 - 1.7e-14 54.0 0.0 1.1e-13 51.3 0.0 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 HET PF06985.6 KEY63975.1 - 3.3e-06 27.3 0.0 5.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF605 PF04652.11 KEY63976.1 - 3.9 6.7 5.0 5.5 6.2 3.4 1.1 1 0 0 1 1 1 0 Vta1 like FLILHELTA PF10306.4 KEY63977.1 - 3.7e-30 103.8 0.0 6.8e-30 102.9 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 KEY63977.1 - 0.0033 17.7 0.4 0.0046 17.2 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) NDK PF00334.14 KEY63978.1 - 1.3e-54 183.6 0.0 1.6e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.21 KEY63979.1 - 4.3e-149 497.1 2.3 6.1e-149 496.6 1.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KEY63979.1 - 4.8e-25 87.2 0.3 1.1e-24 86.0 0.2 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like PsiA PF06952.6 KEY63979.1 - 0.084 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 PsiA protein MS_channel PF00924.13 KEY63980.1 - 4.6e-20 71.8 1.2 7.6e-20 71.1 0.8 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KEY63980.1 - 0.00021 20.3 0.3 0.00052 19.1 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 KEY63980.1 - 0.01 15.4 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.1 KEY63980.1 - 0.013 15.6 0.1 0.038 14.1 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 KEY63980.1 - 0.015 15.1 0.1 0.037 13.8 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.1 KEY63980.1 - 0.038 13.3 0.2 0.1 11.9 0.2 1.7 1 0 0 1 1 1 0 EF hand DUF3671 PF12420.3 KEY63980.1 - 0.043 13.7 0.5 0.2 11.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function BRCT PF00533.21 KEY63981.1 - 2.5e-06 27.5 0.0 7.8e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain ETF_QO PF05187.8 KEY63982.1 - 9.8e-45 151.0 0.0 1.6e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 KEY63982.1 - 1.7e-08 33.7 1.9 0.00036 19.5 0.2 2.5 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY63982.1 - 1.8e-07 31.0 0.0 4.7e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEY63982.1 - 4.4e-05 22.5 2.7 0.0036 16.2 1.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 KEY63982.1 - 6.1e-05 22.9 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEY63982.1 - 0.00055 19.1 0.1 0.0021 17.2 0.1 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KEY63982.1 - 0.00072 18.1 0.5 0.0011 17.5 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 KEY63982.1 - 0.0008 18.5 0.1 0.0016 17.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KEY63982.1 - 0.00083 19.1 0.1 0.0051 16.6 0.1 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KEY63982.1 - 0.0019 18.5 0.0 4.3 7.7 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEY63982.1 - 0.0024 16.9 0.9 0.0049 15.9 0.6 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KEY63982.1 - 0.0069 15.0 0.1 0.17 10.4 0.1 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 KEY63982.1 - 0.01 15.9 0.1 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY63982.1 - 0.029 13.3 0.4 0.044 12.6 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 KEY63982.1 - 0.13 11.0 0.2 0.2 10.4 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF3242 PF11586.3 KEY63982.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) TBP PF00352.16 KEY63983.1 - 2.7e-70 231.7 0.1 4.2e-35 118.9 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KEY63983.1 - 0.00018 21.5 0.0 0.82 9.7 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Pollen_allerg_2 PF01620.11 KEY63983.1 - 0.0022 18.3 0.2 0.003 17.8 0.2 1.3 1 0 0 1 1 1 1 Ribonuclease (pollen allergen) DAO PF01266.19 KEY63984.1 - 3.2e-45 154.5 0.8 4.2e-45 154.2 0.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KEY63984.1 - 2.4e-05 24.1 0.4 0.11 12.2 0.0 2.5 2 1 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.17 KEY63984.1 - 4.6e-05 22.4 0.0 0.001 18.0 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KEY63984.1 - 0.00013 21.9 0.1 0.00057 19.8 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KEY63984.1 - 0.027 13.4 0.0 4.8 5.9 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Surp PF01805.15 KEY63985.1 - 6.4e-14 51.3 0.0 1.2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Surp module RRM_6 PF14259.1 KEY63985.1 - 0.08 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Copper-fist PF00649.13 KEY63986.1 - 4.4e-18 64.1 0.5 8.9e-18 63.2 0.4 1.5 1 0 0 1 1 1 1 Copper fist DNA binding domain Metallothio_2 PF01439.13 KEY63986.1 - 1.7 9.2 24.7 0.19 12.2 1.8 4.0 3 1 0 3 3 3 0 Metallothionein Methyltransf_16 PF10294.4 KEY63987.1 - 2.2e-13 50.0 0.0 3.3e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KEY63987.1 - 0.046 14.3 0.0 0.14 12.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain EcoR124_C PF12008.3 KEY63987.1 - 1.8 7.6 10.4 0.66 9.1 0.7 2.3 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal PhyH PF05721.8 KEY63988.1 - 3.2e-12 46.9 0.0 4.9e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans PF04082.13 KEY63989.1 - 9.5e-11 41.0 0.9 6.8e-10 38.2 0.6 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KEY63989.1 - 9.7e-09 35.0 10.7 0.00049 20.2 0.5 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY63989.1 - 3.8e-07 29.9 10.8 0.0011 19.0 2.6 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEY63989.1 - 2.6e-06 27.4 16.8 1.3e-05 25.2 2.6 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KEY63989.1 - 0.012 15.7 1.9 0.77 9.9 0.6 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 KEY63989.1 - 0.62 9.7 5.1 8.1 6.2 1.2 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Nop14 PF04147.7 KEY63990.1 - 0.17 9.7 19.1 0.22 9.4 13.2 1.2 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 KEY63990.1 - 0.91 8.6 15.5 1.4 7.9 10.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2890 PF11081.3 KEY63990.1 - 5.6 6.9 10.5 8.2 6.4 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Pol_alpha_B_N PF08418.5 KEY63991.1 - 7.2e-54 182.9 0.0 9.6e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 KEY63991.1 - 6.3e-42 143.1 0.1 8.8e-42 142.7 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Prp19_bind PF06991.6 KEY63992.1 - 1.7e-36 125.9 30.5 1.7e-36 125.9 21.2 2.2 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain Y2_Tnp PF04986.8 KEY63992.1 - 3 7.5 5.2 9.9 5.8 3.6 1.9 1 1 0 1 1 1 0 Putative transposase RmlD_sub_bind PF04321.12 KEY63993.1 - 7.3e-51 172.7 0.0 8.9e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KEY63993.1 - 5e-21 75.2 0.0 9.3e-21 74.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KEY63993.1 - 2e-10 40.0 0.0 1.7e-08 33.7 0.0 2.6 2 1 1 3 3 3 1 Male sterility protein Polysacc_synt_2 PF02719.10 KEY63993.1 - 2.4e-07 29.9 0.0 0.0013 17.6 0.0 3.1 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KEY63993.1 - 5.3e-07 28.6 0.0 2e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KEY63993.1 - 0.00049 20.1 0.0 0.00073 19.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KEY63993.1 - 0.041 13.7 1.7 0.64 9.9 1.2 2.4 1 1 0 1 1 1 0 short chain dehydrogenase PH PF00169.24 KEY63994.1 - 0.00052 20.1 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 PH domain polyprenyl_synt PF00348.12 KEY63995.1 - 3.9e-71 238.9 0.0 4.6e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase APC8 PF04049.8 KEY63996.1 - 9.8e-50 168.0 0.8 2.9e-49 166.4 0.0 2.1 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 KEY63996.1 - 1.2e-21 75.2 6.2 7e-05 22.2 0.0 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEY63996.1 - 3.3e-19 68.3 6.4 6.8e-09 35.2 0.2 6.6 4 1 2 6 6 6 4 TPR repeat TPR_8 PF13181.1 KEY63996.1 - 1.8e-18 64.8 5.3 0.00025 20.5 0.0 7.1 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 KEY63996.1 - 4e-15 54.4 15.6 0.028 14.3 0.0 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 KEY63996.1 - 1.9e-11 43.7 15.9 8e-05 22.5 0.3 6.8 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 KEY63996.1 - 7.2e-11 41.7 8.7 0.024 15.2 0.0 8.3 7 3 2 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEY63996.1 - 3.7e-09 37.0 12.3 1.9e-05 25.1 0.2 7.2 6 2 2 8 8 8 1 Tetratricopeptide repeat Apc3 PF12895.2 KEY63996.1 - 3.9e-09 36.5 2.7 0.0088 16.1 0.0 5.6 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KEY63996.1 - 9.7e-08 31.2 6.7 0.09 12.6 0.0 5.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEY63996.1 - 1.4e-07 31.7 2.4 9.1 6.7 0.1 6.6 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.1 KEY63996.1 - 1.2e-05 25.0 9.6 1.5 8.7 0.1 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 KEY63996.1 - 1.8e-05 24.8 18.8 0.3 11.6 0.2 9.6 11 1 0 11 11 9 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEY63996.1 - 2.2e-05 24.3 0.1 1.9 8.9 0.0 5.4 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.2 KEY63996.1 - 0.00081 19.2 2.5 0.021 14.6 0.1 3.2 2 1 1 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_15 PF13429.1 KEY63996.1 - 0.003 16.6 3.8 0.017 14.1 1.7 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat DUF2424 PF10340.4 KEY63996.1 - 0.056 12.0 0.0 0.092 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) MIT PF04212.13 KEY63996.1 - 0.42 10.5 0.0 0.42 10.5 0.0 2.7 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain Far-17a_AIG1 PF04750.9 KEY63997.1 - 0.1 11.7 0.9 0.11 11.6 0.0 1.4 2 0 0 2 2 2 0 FAR-17a/AIG1-like protein Vps54 PF07928.7 KEY63998.1 - 2.1e-47 160.6 1.8 4.4e-46 156.3 0.0 3.1 3 0 0 3 3 3 1 Vps54-like protein DUF2450 PF10475.4 KEY63998.1 - 2.8e-06 26.4 1.5 3.5e-06 26.1 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Sec8_exocyst PF04048.9 KEY63998.1 - 0.094 12.3 4.5 0.84 9.2 0.3 3.3 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Cytochrom_B562 PF07361.6 KEY63998.1 - 0.29 11.5 7.5 3 8.3 0.4 3.9 4 0 0 4 4 4 0 Cytochrome b562 LUC7 PF03194.10 KEY63998.1 - 1.7 8.0 6.5 0.76 9.2 1.6 2.2 2 0 0 2 2 2 0 LUC7 N_terminus DUF904 PF06005.7 KEY63998.1 - 3 8.2 14.4 0.12 12.6 1.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF904) COG2 PF06148.6 KEY63998.1 - 5.2 6.9 10.6 0.55 10.0 1.4 3.4 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 MCM PF00493.18 KEY63999.1 - 1.2e-141 471.3 0.2 1.6e-141 470.9 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KEY63999.1 - 3.6e-19 69.4 0.6 1.3e-18 67.6 0.2 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KEY63999.1 - 7.3e-07 28.5 0.0 0.00016 20.8 0.0 2.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KEY63999.1 - 2.4e-05 24.0 0.0 5.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KEY63999.1 - 0.00024 20.6 0.0 0.001 18.7 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KEY63999.1 - 0.045 13.2 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_2 PF13335.1 KEY63999.1 - 0.052 13.9 0.3 0.052 13.9 0.2 2.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 KEY63999.1 - 0.063 13.4 0.2 0.3 11.2 0.0 2.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PAS_9 PF13426.1 KEY64000.1 - 4.6e-16 59.0 0.0 6.1e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 KEY64000.1 - 8.7e-05 22.2 0.0 0.00014 21.6 0.0 1.4 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.1 KEY64000.1 - 0.00047 19.9 0.0 0.00094 18.9 0.0 1.5 1 0 0 1 1 1 1 PAS domain RAM PF15320.1 KEY64000.1 - 0.026 14.7 0.3 0.046 14.0 0.2 1.4 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein PAS_3 PF08447.6 KEY64000.1 - 0.033 14.2 0.0 0.092 12.8 0.0 1.7 2 0 0 2 2 2 0 PAS fold PAS_4 PF08448.5 KEY64000.1 - 0.079 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 PAS fold Fapy_DNA_glyco PF01149.19 KEY64001.1 - 1.1e-27 96.7 0.1 1.1e-27 96.7 0.1 1.7 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 KEY64001.1 - 1.4e-21 76.0 0.0 2.7e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 KEY64001.1 - 0.00045 18.8 0.0 0.0021 16.6 0.0 1.9 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NUC153 PF08159.7 KEY64002.1 - 4.2e-13 48.6 0.8 7.8e-13 47.7 0.6 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 KEY64002.1 - 1.6e-06 27.7 0.1 0.00017 21.3 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF3568 PF12092.3 KEY64002.1 - 0.097 12.3 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) CD99L2 PF12301.3 KEY64003.1 - 0.0038 16.9 0.1 0.0055 16.4 0.0 1.3 1 0 0 1 1 1 1 CD99 antigen like protein 2 SNN_transmemb PF09049.5 KEY64003.1 - 0.081 12.6 7.8 0.14 11.8 5.4 1.4 1 0 0 1 1 1 0 Stannin transmembrane R_equi_Vir PF05526.6 KEY64003.1 - 1.4 8.5 5.0 0.46 10.1 1.1 1.8 2 0 0 2 2 2 0 Rhodococcus equi virulence-associated protein HALZ PF02183.13 KEY64004.1 - 0.00046 19.8 2.7 0.0024 17.5 0.0 3.0 2 0 0 2 2 2 1 Homeobox associated leucine zipper Syntaxin-18_N PF10496.4 KEY64004.1 - 0.1 12.4 4.7 0.075 12.8 0.8 2.7 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Ribosomal_L33 PF00471.15 KEY64005.1 - 0.00015 21.9 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L33 Aminotran_1_2 PF00155.16 KEY64006.1 - 9.7e-38 130.0 0.0 1.5e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4350 PF14258.1 KEY64006.1 - 0.0031 17.6 0.0 0.0066 16.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4350) RPN7 PF10602.4 KEY64007.1 - 3.8e-56 189.2 1.9 4e-56 189.1 0.3 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 KEY64007.1 - 1.4e-14 54.3 0.0 3.4e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 KEY64007.1 - 0.086 12.6 0.4 0.5 10.2 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat AurF PF11583.3 KEY64008.1 - 0.012 14.5 0.1 0.012 14.5 0.1 1.1 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF Pox_MCEL PF03291.11 KEY64009.1 - 5.5e-65 219.4 0.0 2.3e-46 158.2 0.0 2.4 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 KEY64009.1 - 5.5e-09 36.4 0.0 0.0021 18.5 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 KEY64009.1 - 7.3e-08 32.2 0.0 1.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY64009.1 - 2.4e-07 31.3 0.2 6.2e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY64009.1 - 3.8e-07 30.4 0.0 2.6e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY64009.1 - 1.6e-06 28.3 0.0 3.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY64009.1 - 2.2e-06 27.3 0.0 7.3e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KEY64009.1 - 0.00037 19.5 0.0 0.00058 18.9 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Raftlin PF15250.1 KEY64009.1 - 0.03 12.8 0.1 0.093 11.2 0.0 1.7 2 0 0 2 2 2 0 Raftlin Methyltransf_26 PF13659.1 KEY64009.1 - 0.045 13.7 0.3 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 KEY64009.1 - 0.12 11.3 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Miro PF08477.8 KEY64010.1 - 2.1e-34 118.5 0.0 5.1e-18 65.7 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 KEY64010.1 - 8.8e-34 115.1 0.0 1.9e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 KEY64010.1 - 3e-31 106.5 0.1 7.9e-31 105.1 0.0 1.8 2 0 0 2 2 1 1 EF hand associated Ras PF00071.17 KEY64010.1 - 8.9e-23 80.4 0.0 3.1e-14 52.6 0.0 2.1 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 KEY64010.1 - 1.1e-08 35.0 0.0 0.0014 18.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 KEY64010.1 - 9.4e-08 32.0 1.7 0.00077 19.5 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair AAA_22 PF13401.1 KEY64010.1 - 2.7e-07 30.7 0.0 0.027 14.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain EF-hand_1 PF00036.27 KEY64010.1 - 8.4e-07 27.8 5.9 0.0078 15.4 0.4 2.6 2 0 0 2 2 2 2 EF hand AAA_16 PF13191.1 KEY64010.1 - 1.3e-06 28.5 0.0 0.016 15.2 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain EF-hand_6 PF13405.1 KEY64010.1 - 2.2e-06 27.0 5.1 0.019 14.8 0.4 2.6 2 0 0 2 2 2 2 EF-hand domain Dynamin_N PF00350.18 KEY64010.1 - 1e-05 25.4 0.1 0.02 14.7 0.1 3.0 2 1 1 3 3 3 1 Dynamin family AAA_24 PF13479.1 KEY64010.1 - 0.00014 21.4 0.0 0.092 12.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEY64010.1 - 0.00022 20.7 0.0 0.21 11.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain MobB PF03205.9 KEY64010.1 - 0.00023 20.8 0.0 0.24 11.0 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 KEY64010.1 - 0.00035 20.0 0.0 2 7.8 0.0 3.1 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KEY64010.1 - 0.0012 19.1 0.0 2.2 8.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter EF-hand_5 PF13202.1 KEY64010.1 - 0.0019 17.4 10.7 0.1 12.0 1.6 2.7 2 0 0 2 2 2 2 EF hand DUF258 PF03193.11 KEY64010.1 - 0.002 17.3 0.0 0.56 9.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KEY64010.1 - 0.0024 17.7 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KEY64010.1 - 0.0031 17.6 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 KEY64010.1 - 0.0032 17.4 0.0 2.8 7.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KEY64010.1 - 0.0035 16.9 0.0 0.19 11.2 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 KEY64010.1 - 0.0074 15.9 0.0 2.9 7.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.1 KEY64010.1 - 0.011 15.0 0.0 5 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 KEY64010.1 - 0.012 14.7 0.0 0.15 11.0 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_10 PF12846.2 KEY64010.1 - 0.016 14.6 0.0 5.7 6.2 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain cobW PF02492.14 KEY64010.1 - 0.017 14.5 0.0 3.7 6.9 0.0 3.8 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.8 KEY64010.1 - 0.02 13.8 0.0 1.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) EF-hand_10 PF14788.1 KEY64010.1 - 0.03 13.9 0.9 0.098 12.3 0.1 2.0 2 0 0 2 2 2 0 EF hand AIG1 PF04548.11 KEY64010.1 - 0.045 12.8 0.0 0.88 8.6 0.1 2.3 2 0 0 2 2 2 0 AIG1 family AAA PF00004.24 KEY64010.1 - 0.082 13.1 0.1 7.9 6.6 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 KEY64010.1 - 0.083 12.4 0.1 33 3.8 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 KEY64010.1 - 0.084 12.5 0.0 6.1 6.4 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 KEY64010.1 - 0.12 12.7 0.0 12 6.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KEY64010.1 - 0.13 11.3 0.0 2.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 KEY64010.1 - 0.15 12.9 0.0 26 5.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain IIGP PF05049.8 KEY64010.1 - 0.15 10.8 0.0 1.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) WD40 PF00400.27 KEY64011.1 - 1.6e-20 72.1 13.0 2.6e-05 23.9 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat IKI3 PF04762.7 KEY64011.1 - 0.015 13.1 0.0 0.019 12.7 0.0 1.3 1 0 0 1 1 1 0 IKI3 family eIF2A PF08662.6 KEY64011.1 - 0.039 13.6 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KEY64011.1 - 0.055 11.7 0.0 0.097 10.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain MFS_1 PF07690.11 KEY64013.1 - 9.2e-38 129.8 65.2 2.9e-32 111.7 36.2 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.14 KEY64013.1 - 1.4e-05 23.8 4.1 0.0046 15.5 0.0 2.4 2 0 0 2 2 2 2 LacY proton/sugar symporter DUF1129 PF06570.6 KEY64013.1 - 0.064 12.5 1.4 0.18 11.0 1.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF1298 PF06974.8 KEY64013.1 - 0.066 13.0 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) DUF3149 PF11346.3 KEY64013.1 - 6.3 6.4 9.5 16 5.1 0.1 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3149) TIL PF01826.12 KEY64014.1 - 9.5e-15 54.4 17.4 1.2e-14 54.1 12.1 1.1 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain cEGF PF12662.2 KEY64014.1 - 0.11 12.1 0.6 0.11 12.1 0.4 2.0 2 0 0 2 2 2 0 Complement Clr-like EGF-like RGS PF00615.14 KEY64015.1 - 9.1e-08 32.2 0.2 2.5e-05 24.3 0.0 2.3 2 1 0 2 2 2 2 Regulator of G protein signaling domain DUF4066 PF13278.1 KEY64016.1 - 2.1e-34 118.1 0.0 2.6e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KEY64016.1 - 3.6e-12 45.9 0.0 4.9e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 KEY64016.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Ank_2 PF12796.2 KEY64017.1 - 2.8e-20 72.4 0.0 3.6e-10 40.0 0.0 5.8 3 2 3 6 6 6 4 Ankyrin repeats (3 copies) Ank PF00023.25 KEY64017.1 - 6.6e-16 57.2 2.1 0.00059 19.5 0.0 8.5 8 2 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.1 KEY64017.1 - 2.2e-15 56.6 0.9 0.21 12.1 0.0 6.7 4 3 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY64017.1 - 5.3e-10 38.5 0.2 0.0051 16.9 0.0 6.7 7 0 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.1 KEY64017.1 - 1.2e-07 31.7 3.2 0.11 12.7 0.0 5.5 4 2 1 5 5 5 3 Ankyrin repeats (many copies) NACHT PF05729.7 KEY64017.1 - 0.00093 18.8 0.1 0.0027 17.4 0.1 1.8 1 1 1 2 2 2 1 NACHT domain AAA_17 PF13207.1 KEY64017.1 - 0.015 16.1 0.1 0.098 13.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KEY64017.1 - 0.036 13.7 0.0 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 KEY64017.1 - 0.063 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Glyco_hyd_65N_2 PF14498.1 KEY64018.1 - 4.5e-48 163.9 0.0 6.8e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.10 KEY64018.1 - 0.0044 15.7 0.1 0.0044 15.7 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 KEY64018.1 - 0.0047 16.2 0.0 0.0082 15.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Acetyltransf_1 PF00583.19 KEY64019.1 - 3.2e-12 46.3 0.3 5.7e-12 45.4 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEY64019.1 - 2.4e-10 40.4 0.0 4.2e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEY64019.1 - 2.1e-05 24.6 0.1 2.9e-05 24.1 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEY64019.1 - 0.0035 17.1 0.0 0.0071 16.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 KEY64019.1 - 0.094 12.0 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Acetyltransf_3 PF13302.1 KEY64019.1 - 0.13 12.3 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1212 PF06738.7 KEY64020.1 - 4.1e-50 169.9 9.0 1.3e-48 165.0 0.2 2.7 4 0 0 4 4 4 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KEY64020.1 - 2e-30 105.4 32.6 1.3e-29 102.7 8.8 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) DUF3366 PF11846.3 KEY64020.1 - 0.13 12.1 1.6 0.55 10.0 1.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) DUF2301 PF10063.4 KEY64020.1 - 1.8 8.8 8.2 0.35 11.0 2.3 2.2 2 0 0 2 2 2 0 Uncharacterized integral membrane protein (DUF2301) DLH PF01738.13 KEY64021.1 - 2.7e-27 95.4 0.0 3.3e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KEY64021.1 - 8e-07 28.9 0.0 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY64021.1 - 0.0096 15.8 0.0 0.54 10.0 0.0 2.3 1 1 0 2 2 2 1 Alpha/beta hydrolase family SnoaL PF07366.7 KEY64022.1 - 7e-06 25.6 0.1 1.1e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KEY64022.1 - 0.00023 21.5 0.3 0.00044 20.5 0.2 1.4 1 0 0 1 1 1 1 SnoaL-like domain Aldo_ket_red PF00248.16 KEY64023.1 - 8.4e-41 139.6 0.0 1e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Pyr_redox_3 PF13738.1 KEY64024.1 - 6.4e-25 88.4 0.0 1.1e-23 84.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEY64024.1 - 3.2e-14 53.2 0.0 1.1e-10 41.6 0.0 3.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEY64024.1 - 4.1e-13 48.9 0.1 3e-10 39.5 0.1 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KEY64024.1 - 2.8e-12 45.6 0.2 2.9e-11 42.2 0.1 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox PF00070.22 KEY64024.1 - 8.2e-09 35.7 0.1 0.0011 19.3 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY64024.1 - 4.1e-08 33.1 0.0 1.2e-06 28.3 0.0 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KEY64024.1 - 8.3e-07 28.3 0.3 3.3e-05 23.1 0.0 2.8 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.17 KEY64024.1 - 6.4e-06 25.2 0.4 0.0017 17.2 0.1 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.14 KEY64024.1 - 9.7e-06 24.8 0.0 0.0024 17.0 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 KEY64024.1 - 1e-05 24.2 0.3 0.00041 18.9 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein Shikimate_DH PF01488.15 KEY64024.1 - 1.1e-05 25.5 0.1 0.18 11.8 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 KEY64024.1 - 1.3e-05 24.3 1.9 0.018 13.9 0.2 3.4 4 0 0 4 4 4 2 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KEY64024.1 - 4.2e-05 23.2 0.1 0.014 15.0 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KEY64024.1 - 5.4e-05 23.3 0.0 0.037 14.2 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 KEY64024.1 - 8.4e-05 21.5 1.3 0.00026 19.9 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 KEY64024.1 - 0.00049 19.7 0.4 0.03 13.9 0.0 2.7 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KEY64024.1 - 0.0018 17.4 0.1 0.032 13.3 0.0 2.6 2 1 1 3 3 3 1 Thi4 family ELFV_dehydrog PF00208.16 KEY64024.1 - 0.0061 16.1 0.4 0.024 14.2 0.0 2.0 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CPSase_L_chain PF00289.17 KEY64024.1 - 0.0062 16.6 0.0 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain ThiF PF00899.16 KEY64024.1 - 0.0066 16.2 0.5 0.026 14.3 0.2 2.0 2 0 0 2 2 2 1 ThiF family FAD_oxidored PF12831.2 KEY64024.1 - 0.0079 15.3 0.1 0.013 14.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KEY64024.1 - 0.0088 15.8 0.0 2.5 7.8 0.0 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding TrkA_N PF02254.13 KEY64024.1 - 0.02 14.9 0.1 0.86 9.6 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Lycopene_cycl PF05834.7 KEY64024.1 - 0.026 13.4 0.1 0.096 11.5 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein DEAD PF00270.24 KEY64024.1 - 0.035 13.6 0.0 0.087 12.3 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase IlvN PF07991.7 KEY64024.1 - 0.037 13.3 0.1 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 KEY64024.1 - 0.12 12.0 0.1 6 6.5 0.0 2.9 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ADH_N PF08240.7 KEY64025.1 - 1.1e-26 92.7 3.2 1.1e-26 92.7 2.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY64025.1 - 1.1e-17 63.7 0.0 1.9e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PIN PF01850.16 KEY64025.1 - 0.0031 17.8 0.0 0.0055 17.0 0.0 1.4 1 0 0 1 1 1 1 PIN domain ADH_zinc_N_2 PF13602.1 KEY64025.1 - 0.057 14.3 0.0 0.13 13.1 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KEY64025.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.11 KEY64026.1 - 1.5e-35 122.5 27.3 2.2e-35 122.0 18.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily HpcH_HpaI PF03328.9 KEY64027.1 - 2.3e-42 144.3 0.0 2.9e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.1 KEY64027.1 - 0.0061 15.8 1.2 0.081 12.1 0.1 2.9 2 1 1 3 3 3 1 Phosphoenolpyruvate phosphomutase Zn_clus PF00172.13 KEY64028.1 - 1.9e-09 37.2 10.0 1.9e-09 37.2 7.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY64028.1 - 0.025 13.4 3.2 0.27 10.0 0.1 2.8 2 1 1 3 3 3 0 Fungal specific transcription factor domain Nsp1_C PF05064.8 KEY64028.1 - 0.036 13.7 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 Nsp1-like C-terminal region Rrn6 PF10214.4 KEY64028.1 - 0.17 9.9 2.3 0.15 10.0 0.7 1.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor Snf7 PF03357.16 KEY64028.1 - 0.24 10.7 0.3 0.85 8.9 0.2 1.9 1 1 0 1 1 1 0 Snf7 IncA PF04156.9 KEY64028.1 - 5.1 6.6 7.4 0.38 10.3 0.5 2.3 3 0 0 3 3 3 0 IncA protein Clr5 PF14420.1 KEY64029.1 - 3.9e-06 26.6 0.9 1.2e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Clr5 domain Dynamin_N PF00350.18 KEY64030.1 - 1.3e-22 80.4 0.0 2.9e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KEY64030.1 - 3.8e-10 39.0 1.2 5.6e-10 38.4 0.1 1.9 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 KEY64030.1 - 3.8e-05 23.5 0.0 0.00022 21.1 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEY64030.1 - 0.0025 18.2 0.0 0.0095 16.4 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein AAA_21 PF13304.1 KEY64030.1 - 0.012 15.6 0.0 0.086 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain FAD_binding_3 PF01494.14 KEY64031.1 - 7.3e-17 61.4 0.9 4.1e-16 58.9 0.7 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KEY64031.1 - 1e-08 35.0 0.6 2.2e-08 34.0 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEY64031.1 - 5.1e-08 32.2 0.2 9.3e-08 31.3 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KEY64031.1 - 6.9e-06 25.3 0.0 0.014 14.5 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 KEY64031.1 - 2.6e-05 24.1 0.2 5.9e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY64031.1 - 3e-05 24.3 0.6 3e-05 24.3 0.4 2.1 3 0 0 3 3 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY64031.1 - 0.0012 17.8 0.1 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KEY64031.1 - 0.0013 17.6 3.5 0.0058 15.5 2.5 1.9 1 1 1 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KEY64031.1 - 0.0028 16.7 0.1 0.0039 16.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KEY64031.1 - 0.015 14.2 1.9 0.026 13.4 1.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 KEY64031.1 - 0.021 14.4 1.8 0.045 13.3 1.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KEY64031.1 - 0.022 14.4 0.5 0.043 13.5 0.3 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 KEY64031.1 - 0.035 12.7 1.5 0.6 8.6 0.6 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_2 PF03446.10 KEY64031.1 - 0.045 13.5 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_3 PF13738.1 KEY64031.1 - 0.054 13.5 1.2 0.11 12.5 0.8 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.4 KEY64031.1 - 0.061 13.0 0.3 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 Rossmann-like domain ApbA PF02558.11 KEY64031.1 - 0.22 10.9 0.9 0.55 9.6 0.6 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 KEY64031.1 - 0.53 8.6 4.0 0.23 9.8 1.2 1.5 2 0 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.11 KEY64032.1 - 9.2e-25 87.0 28.4 3.9e-24 85.0 20.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily GST_N_2 PF13409.1 KEY64033.1 - 1.3e-18 66.6 0.0 3.5e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEY64033.1 - 4.3e-10 39.3 0.0 6.2e-09 35.6 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KEY64033.1 - 0.00015 21.9 0.0 0.11 12.7 0.0 2.6 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KEY64033.1 - 0.0014 19.0 0.0 0.0024 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KEY64033.1 - 0.054 13.4 0.0 0.14 12.1 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Aldo_ket_red PF00248.16 KEY64034.1 - 7e-50 169.4 0.0 8.3e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Alliinase_C PF04864.8 KEY64034.1 - 0.017 13.8 0.0 0.027 13.1 0.0 1.2 1 0 0 1 1 1 0 Allinase adh_short PF00106.20 KEY64035.1 - 7.7e-09 35.6 0.4 1.2e-08 35.1 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY64035.1 - 9.6e-09 35.3 0.0 3e-07 30.4 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase p450 PF00067.17 KEY64036.1 - 1e-53 182.5 0.0 1.3e-53 182.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tri3 PF07428.6 KEY64037.1 - 1.4e-120 402.8 0.0 1.7e-120 402.5 0.0 1.0 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 AATase PF07247.7 KEY64037.1 - 0.00041 19.0 0.0 0.00084 17.9 0.0 1.4 1 1 0 1 1 1 1 Alcohol acetyltransferase Fungal_trans_2 PF11951.3 KEY64038.1 - 2e-52 178.0 2.5 2.5e-52 177.7 1.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Phage_holin_T PF11031.3 KEY64038.1 - 0.069 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage T holin zf-C2H2_4 PF13894.1 KEY64039.1 - 4e-06 26.7 13.8 0.14 12.5 0.4 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY64039.1 - 0.012 15.9 0.4 0.012 15.9 0.3 4.1 5 0 0 5 5 5 0 Zinc finger, C2H2 type ketoacyl-synt PF00109.21 KEY64040.1 - 3.9e-57 193.6 0.2 1.4e-56 191.8 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEY64040.1 - 6.6e-54 183.3 0.1 1.3e-53 182.3 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KEY64040.1 - 4.3e-40 137.7 0.0 9.1e-40 136.6 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 KEY64040.1 - 4e-35 121.1 0.5 1.1e-34 119.6 0.3 1.9 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KEY64040.1 - 3.6e-24 85.5 1.3 2e-23 83.1 0.9 2.4 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 KEY64040.1 - 1e-06 28.9 0.0 2.6e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 KEY64040.1 - 1e-05 25.9 0.0 3.1e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY64040.1 - 1.7e-05 24.5 0.0 5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ketoacyl-synt_C PF02801.17 KEY64040.1 - 0.00014 21.7 0.0 0.00061 19.6 0.0 2.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_11 PF08241.7 KEY64040.1 - 0.001 19.5 0.0 0.0072 16.7 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY64040.1 - 0.016 15.7 1.1 0.37 11.3 0.0 3.3 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_31 PF13847.1 KEY64040.1 - 0.024 14.2 0.0 0.089 12.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain ADH_N PF08240.7 KEY64040.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Tri3 PF07428.6 KEY64041.1 - 1.2e-56 192.1 0.0 1.5e-56 191.9 0.0 1.0 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 p450 PF00067.17 KEY64042.1 - 5e-74 249.5 0.0 5.7e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TRI5 PF06330.6 KEY64043.1 - 2.1e-214 711.1 3.1 2.6e-214 710.8 2.1 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) DUF1816 PF08846.5 KEY64043.1 - 0.0055 16.3 0.1 0.034 13.8 0.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF1816) DUF2215 PF10225.4 KEY64043.1 - 0.13 11.6 0.1 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) TauD PF02668.11 KEY64045.1 - 1.5e-26 93.6 0.0 1.8e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KEY64045.1 - 0.16 10.8 0.1 0.41 9.4 0.0 1.7 2 0 0 2 2 2 0 CsiD Methyltransf_2 PF00891.13 KEY64046.1 - 2.8e-22 79.0 0.0 4e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KEY64046.1 - 0.0012 19.3 0.0 0.0071 16.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY64046.1 - 0.0084 15.7 0.0 0.052 13.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain DUF877 PF05943.7 KEY64046.1 - 0.056 11.9 0.0 0.097 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF877) Acetyltransf_1 PF00583.19 KEY64047.1 - 2e-05 24.4 0.0 3.5e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KEY64047.1 - 9.7e-05 22.4 0.0 0.0015 18.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KEY64047.1 - 0.00051 20.1 0.0 0.0015 18.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEY64047.1 - 0.0036 17.1 0.0 0.056 13.3 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Mec-17 PF05301.6 KEY64047.1 - 0.027 14.4 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Touch receptor neuron protein Mec-17 Zn_clus PF00172.13 KEY64048.1 - 0.011 15.6 4.6 0.025 14.4 3.2 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KEY64049.1 - 6.5e-17 61.2 35.7 1.5e-14 53.4 7.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ODV-E18 PF10717.4 KEY64049.1 - 0.1 12.0 0.1 0.1 12.0 0.1 2.5 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 DUF2419 PF10343.4 KEY64050.1 - 1e-103 346.5 0.0 1.3e-103 346.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) DNA_pol_delta_4 PF04081.8 KEY64051.1 - 1.2e-30 106.3 2.5 2e-30 105.6 1.8 1.6 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 WD40 PF00400.27 KEY64052.1 - 6.1e-28 95.6 18.2 2e-12 46.4 0.7 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Ribosomal_L32p PF01783.18 KEY64052.1 - 5.2e-10 39.3 6.7 5.2e-10 39.3 4.6 1.6 2 0 0 2 2 2 1 Ribosomal L32p protein family eIF2A PF08662.6 KEY64052.1 - 0.0022 17.7 0.0 0.018 14.7 0.0 2.3 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KEY64052.1 - 0.003 15.9 0.1 0.012 13.9 0.1 1.8 1 1 0 1 1 1 1 Cytochrome D1 heme domain Stc1 PF12898.2 KEY64052.1 - 0.043 13.8 1.4 0.086 12.9 0.9 1.4 1 0 0 1 1 1 0 Stc1 domain Nup160 PF11715.3 KEY64052.1 - 0.076 11.1 0.0 0.5 8.4 0.0 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Septin PF00735.13 KEY64053.1 - 1.3e-109 365.5 0.2 1.6e-109 365.2 0.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KEY64053.1 - 5.2e-05 23.1 0.0 9.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KEY64053.1 - 0.00026 20.2 0.0 0.0005 19.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KEY64053.1 - 0.00043 19.4 0.0 0.0008 18.5 0.0 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 KEY64053.1 - 0.0009 18.7 0.2 0.022 14.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KEY64053.1 - 0.013 15.3 0.4 2.6 7.8 0.0 2.4 1 1 1 2 2 2 0 Dynamin family Sugarporin_N PF11471.3 KEY64053.1 - 0.036 13.7 0.0 0.081 12.5 0.0 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension ABC_tran PF00005.22 KEY64053.1 - 0.036 14.3 0.1 0.066 13.5 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Glyco_hydro_72 PF03198.9 KEY64054.1 - 4.8e-108 360.8 0.3 6e-108 360.5 0.2 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 KEY64054.1 - 1.9e-05 23.7 0.1 3.1e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Exostosin PF03016.10 KEY64054.1 - 0.0025 16.9 0.0 0.0039 16.2 0.0 1.2 1 0 0 1 1 1 1 Exostosin family DUF4073 PF13285.1 KEY64054.1 - 0.061 12.7 0.1 11 5.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4073) FlgD_ig PF13860.1 KEY64054.1 - 0.078 12.7 0.3 1.4 8.7 0.1 2.5 2 0 0 2 2 2 0 FlgD Ig-like domain ATP-grasp_2 PF08442.5 KEY64055.1 - 1.8e-07 30.7 0.0 2.9e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CoA_binding PF02629.14 KEY64056.1 - 1.2e-18 67.4 0.0 3.7e-18 65.8 0.0 1.9 1 0 0 1 1 1 1 CoA binding domain Citrate_synt PF00285.16 KEY64056.1 - 1.8e-18 66.4 0.0 9e-16 57.5 0.0 3.0 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 KEY64056.1 - 1.4e-14 54.0 0.4 2.7e-14 53.0 0.1 1.6 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.1 KEY64056.1 - 1.5e-05 24.6 0.0 0.00037 20.1 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain DapB_N PF01113.15 KEY64056.1 - 0.085 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ribosomal_L30 PF00327.15 KEY64057.1 - 2.7e-15 55.6 0.0 3.8e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e MRG PF05712.8 KEY64058.1 - 4.5e-54 182.3 0.2 7.5e-54 181.6 0.2 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 KEY64058.1 - 7.2e-07 28.8 0.2 1.4e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Cnl2_NKP2 PF09447.5 KEY64059.1 - 1e-21 76.3 0.4 2.2e-21 75.3 0.0 1.7 2 0 0 2 2 2 1 Cnl2/NKP2 family protein CENP-F_leu_zip PF10473.4 KEY64059.1 - 0.067 13.0 2.4 0.22 11.3 1.3 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.4 KEY64059.1 - 0.07 13.2 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Spc19 PF08287.6 KEY64059.1 - 0.071 12.7 0.1 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Spc19 GAS PF13851.1 KEY64059.1 - 0.072 12.2 0.3 0.087 12.0 0.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 KEY64059.1 - 0.077 12.4 2.2 0.1 12.0 0.1 2.1 2 1 0 2 2 2 0 Septum formation initiator Med4 PF10018.4 KEY64059.1 - 0.084 12.2 0.5 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Prefoldin_2 PF01920.15 KEY64059.1 - 0.12 12.1 0.1 0.12 12.1 0.1 1.8 2 0 0 2 2 2 0 Prefoldin subunit DUF904 PF06005.7 KEY64059.1 - 0.53 10.6 4.6 3.1 8.1 3.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Seryl_tRNA_N PF02403.17 KEY64059.1 - 1.6 8.8 4.7 17 5.4 3.2 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4400 PF14348.1 KEY64060.1 - 0.009 15.4 0.4 0.017 14.4 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4400) ET PF01684.11 KEY64060.1 - 0.029 14.3 0.2 0.053 13.5 0.1 1.4 1 0 0 1 1 1 0 ET module COP23 PF14218.1 KEY64060.1 - 0.031 13.8 0.3 0.062 12.8 0.1 1.6 2 1 0 2 2 2 0 Circadian oscillating protein COP23 CENP-Q PF13094.1 KEY64061.1 - 3.9e-28 98.4 1.9 3.9e-28 98.4 1.3 1.9 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit CENP-B_dimeris PF09026.5 KEY64062.1 - 1.4 9.1 8.2 2.5 8.4 5.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 KEY64062.1 - 3.7 7.9 6.3 5.9 7.2 4.4 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2435 PF10363.4 KEY64063.1 - 1.4e-11 44.0 0.3 1.2e-10 41.1 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 KEY64063.1 - 2e-11 43.1 0.0 4.6e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) MOR2-PAG1_C PF14225.1 KEY64063.1 - 0.026 14.2 0.7 0.088 12.5 0.2 1.9 2 0 0 2 2 2 0 Cell morphogenesis C-terminal OB_NTP_bind PF07717.11 KEY64065.1 - 6.8e-26 90.3 0.0 2e-25 88.8 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KEY64065.1 - 4e-23 81.3 0.0 1.1e-22 79.9 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KEY64065.1 - 1.3e-10 41.0 0.0 2.9e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEY64065.1 - 2e-06 27.4 0.9 7.4e-06 25.5 0.4 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEY64065.1 - 6.9e-06 26.2 0.0 2e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 KEY64065.1 - 0.0013 18.2 0.1 0.0036 16.7 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SE PF00437.15 KEY64065.1 - 0.0031 16.4 0.0 0.0062 15.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 KEY64065.1 - 0.017 14.9 0.1 3.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 KEY64065.1 - 0.055 13.2 0.2 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain Spore_IV_A PF09547.5 KEY64065.1 - 0.16 10.6 0.0 0.28 9.8 0.0 1.3 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Response_reg PF00072.19 KEY64065.1 - 0.21 11.6 1.5 2.7 8.0 0.2 3.0 3 0 0 3 3 3 0 Response regulator receiver domain PRMT5 PF05185.11 KEY64066.1 - 3.9e-167 556.7 0.0 4.9e-167 556.3 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.11 KEY64066.1 - 0.055 13.0 0.0 0.086 12.4 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein DUF1772 PF08592.6 KEY64066.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Abhydrolase_6 PF12697.2 KEY64067.1 - 1.4e-28 100.3 4.8 1.9e-28 99.9 3.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY64067.1 - 3.9e-18 65.6 0.1 7.4e-18 64.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEY64067.1 - 1.1e-06 28.0 0.2 9.2e-05 21.7 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KEY64067.1 - 1.2e-06 28.2 0.0 5.1e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KEY64067.1 - 0.00072 19.8 0.1 0.0046 17.2 0.0 2.0 1 1 1 2 2 2 1 Thioesterase domain Hydrolase_4 PF12146.3 KEY64067.1 - 0.0013 18.5 0.0 0.0033 17.2 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 KEY64067.1 - 0.0016 18.0 1.2 0.025 14.1 0.4 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.5 KEY64067.1 - 0.0018 17.2 0.0 1.3 7.8 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1749) AXE1 PF05448.7 KEY64067.1 - 0.2 10.1 0.7 0.6 8.5 0.0 1.9 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) PGAP1 PF07819.8 KEY64067.1 - 0.22 11.0 1.2 0.57 9.7 0.9 1.7 1 1 0 1 1 1 0 PGAP1-like protein Aminotran_5 PF00266.14 KEY64068.1 - 1.5e-26 93.0 0.0 2e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 KEY64068.1 - 0.0021 17.9 0.1 0.021 14.6 0.0 2.2 2 0 0 2 2 2 1 B12 binding domain CRM1_C PF08767.6 KEY64069.1 - 1.3e-128 428.4 0.2 1.3e-128 428.4 0.1 3.4 3 2 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 KEY64069.1 - 1.8e-40 138.2 13.0 3.2e-40 137.4 6.2 3.2 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 KEY64069.1 - 2.7e-09 36.7 0.3 2.8e-08 33.5 0.0 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain C8 PF08742.6 KEY64069.1 - 0.069 13.4 1.6 1.1 9.6 0.0 3.1 3 0 0 3 3 3 0 C8 domain Vac14_Fab1_bd PF12755.2 KEY64069.1 - 0.26 11.6 2.8 3.2 8.2 0.0 4.3 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region Zn_clus PF00172.13 KEY64070.1 - 4.3e-07 29.7 8.0 7.2e-07 29.0 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.24 KEY64071.1 - 1e-33 116.1 0.0 2.6e-33 114.9 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY64071.1 - 5.3e-18 64.6 0.0 1.2e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KEY64071.1 - 6.1e-18 64.1 0.0 1.1e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KEY64071.1 - 0.0097 15.7 0.0 0.035 13.9 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KEY64071.1 - 0.031 14.0 0.0 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 KEY64071.1 - 0.075 13.1 0.1 1.1 9.4 0.1 2.4 1 1 0 1 1 1 0 AAA domain RNA_polI_A34 PF08208.6 KEY64071.1 - 1 8.9 9.9 1.7 8.2 6.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 IncFII_repA PF02387.10 KEY64071.1 - 8.2 5.4 12.1 14 4.7 8.4 1.3 1 0 0 1 1 1 0 IncFII RepA protein family CTP_transf_1 PF01148.15 KEY64072.1 - 2.9e-18 66.4 14.7 1.2e-14 54.6 6.3 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family DUF2244 PF10003.4 KEY64072.1 - 3.3 7.0 5.6 0.84 9.0 0.7 2.3 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) KxDL PF10241.4 KEY64073.1 - 8.5e-31 105.7 2.2 1.1e-30 105.3 1.5 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein Mating_C PF12737.2 KEY64073.1 - 0.00012 21.1 1.6 0.008 15.1 0.0 2.1 2 0 0 2 2 2 2 C-terminal domain of homeodomain 1 XylR_N PF06505.6 KEY64073.1 - 0.017 14.5 0.1 0.022 14.1 0.1 1.2 1 0 0 1 1 1 0 Activator of aromatic catabolism Syntaxin PF00804.20 KEY64073.1 - 0.052 13.7 1.2 0.41 10.8 0.0 2.1 1 1 1 2 2 2 0 Syntaxin DUF883 PF05957.8 KEY64073.1 - 2.6 8.4 6.1 11 6.4 3.8 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) MPLKIP PF15502.1 KEY64074.1 - 0.55 10.9 8.6 2.5 8.7 5.9 2.1 1 1 0 1 1 1 0 M-phase-specific PLK1-interacting protein Cir_N PF10197.4 KEY64076.1 - 0.00017 21.5 0.9 0.00017 21.5 0.6 4.4 3 1 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR AAA PF00004.24 KEY64077.1 - 1.7e-50 170.6 0.0 6.1e-39 133.2 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEY64077.1 - 2.9e-10 40.3 0.0 0.00041 20.4 0.0 4.0 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEY64077.1 - 1.5e-08 34.8 0.0 0.0018 18.3 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 KEY64077.1 - 2.5e-07 30.6 0.0 0.0072 16.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 KEY64077.1 - 2.7e-07 29.6 0.0 0.014 14.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus CDC48_2 PF02933.12 KEY64077.1 - 9.6e-07 28.3 0.1 1.7e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_17 PF13207.1 KEY64077.1 - 1.2e-06 29.2 0.0 0.011 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 KEY64077.1 - 1.4e-06 28.2 0.1 0.35 10.5 0.0 4.1 2 2 2 4 4 4 1 Archaeal ATPase AAA_5 PF07728.9 KEY64077.1 - 1.5e-06 27.9 0.0 0.0012 18.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) CDC48_N PF02359.13 KEY64077.1 - 2.1e-06 27.5 0.0 5.6e-06 26.2 0.0 1.7 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_33 PF13671.1 KEY64077.1 - 2.5e-06 27.4 0.0 0.07 12.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 KEY64077.1 - 6.9e-06 26.0 0.0 0.00017 21.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 KEY64077.1 - 1.7e-05 25.1 0.0 0.03 14.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 KEY64077.1 - 5.3e-05 23.3 0.0 0.075 13.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_19 PF13245.1 KEY64077.1 - 7.6e-05 22.3 0.3 0.022 14.4 0.1 2.8 2 0 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 KEY64077.1 - 0.00018 20.6 1.1 0.11 11.4 0.1 3.1 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KEY64077.1 - 0.00031 19.9 0.9 0.0046 16.1 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KEY64077.1 - 0.00056 19.3 0.1 0.17 11.2 0.0 2.8 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_25 PF13481.1 KEY64077.1 - 0.0013 18.1 1.7 0.33 10.3 0.1 3.2 2 1 1 3 3 3 1 AAA domain NACHT PF05729.7 KEY64077.1 - 0.0024 17.5 1.0 6.9 6.2 0.0 3.9 5 0 0 5 5 4 0 NACHT domain AAA_28 PF13521.1 KEY64077.1 - 0.0065 16.4 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 KEY64077.1 - 0.0082 15.2 0.9 0.015 14.4 0.1 1.7 2 0 0 2 2 2 1 KaiC AAA_24 PF13479.1 KEY64077.1 - 0.011 15.3 0.3 0.054 13.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 KEY64077.1 - 0.013 14.3 0.0 1.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 KEY64077.1 - 0.014 14.8 0.1 1.8 7.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.22 KEY64077.1 - 0.025 14.8 0.3 0.38 11.0 0.0 2.6 2 0 0 2 2 2 0 ABC transporter PhoH PF02562.11 KEY64077.1 - 0.049 12.8 0.1 3.3 6.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.1 KEY64077.1 - 0.068 12.7 0.0 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KEY64077.1 - 0.11 11.5 0.4 2.8 6.9 0.0 2.5 3 0 0 3 3 2 0 Zeta toxin DUF2075 PF09848.4 KEY64077.1 - 0.11 11.4 0.1 0.44 9.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IPT PF01745.11 KEY64077.1 - 0.23 10.5 0.2 2.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase NB-ARC PF00931.17 KEY64077.1 - 0.26 10.1 2.3 1.8 7.3 0.1 2.7 3 0 0 3 3 3 0 NB-ARC domain RasGEF PF00617.14 KEY64078.1 - 2.3e-48 164.4 0.1 3.4e-48 163.8 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KEY64078.1 - 1.1e-13 51.1 0.1 2.4e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif Ribosomal_S2 PF00318.15 KEY64079.1 - 6.1e-43 146.5 0.0 6.6e-22 77.7 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_S15 PF00312.17 KEY64080.1 - 4.4e-15 55.1 1.6 5.6e-15 54.8 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S15 vATP-synt_AC39 PF01992.11 KEY64081.1 - 5.4e-116 387.3 0.0 6.1e-116 387.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nop PF01798.13 KEY64082.1 - 3.1e-49 166.1 0.5 6.2e-49 165.1 0.4 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KEY64082.1 - 4.2e-26 90.4 0.2 7.4e-26 89.7 0.1 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KEY64082.1 - 1.8e-21 76.0 2.1 8.5e-21 73.8 1.4 2.3 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Band_7 PF01145.20 KEY64083.1 - 4.8e-27 95.0 2.8 7.8e-27 94.3 2.0 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KEY64083.1 - 0.052 13.0 1.2 0.061 12.8 0.1 1.6 2 0 0 2 2 2 0 SPFH domain-Band 7 family APC10 PF03256.11 KEY64084.1 - 4.8e-48 163.3 0.0 7.5e-48 162.6 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) DUF619 PF04768.8 KEY64084.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF619) Dioxygenase_C PF00775.16 KEY64086.1 - 4.1e-11 42.4 2.1 1.1e-10 41.0 1.4 1.7 1 1 0 1 1 1 1 Dioxygenase MG1 PF11974.3 KEY64086.1 - 0.018 15.5 0.1 0.081 13.4 0.0 2.1 2 0 0 2 2 2 0 Alpha-2-macroglobulin MG1 domain Glyco_hydro_61 PF03443.9 KEY64087.1 - 2.5e-43 148.4 0.0 3.1e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 FAD_binding_3 PF01494.14 KEY64088.1 - 2.8e-20 72.6 0.0 8.6e-20 71.0 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KEY64088.1 - 5.7e-05 22.3 0.0 0.039 13.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 KEY64088.1 - 0.0068 16.7 0.9 0.031 14.6 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KEY64088.1 - 0.01 15.4 0.1 0.023 14.2 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 KEY64088.1 - 0.014 14.3 0.2 1.4 7.7 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY64088.1 - 0.024 14.6 0.1 0.057 13.4 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF4251 PF14059.1 KEY64088.1 - 0.029 14.1 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4251) Lycopene_cycl PF05834.7 KEY64088.1 - 0.035 13.0 0.3 6.8 5.4 0.1 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 KEY64088.1 - 0.078 11.4 2.4 1.2 7.5 0.1 2.4 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.1 KEY64088.1 - 0.082 12.9 0.5 0.25 11.3 0.2 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEY64088.1 - 0.19 10.5 0.2 0.32 9.7 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain bZIP_1 PF00170.16 KEY64089.1 - 5.9e-07 29.3 2.1 1.6e-06 27.9 1.5 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KEY64089.1 - 1.7e-05 24.5 2.3 1.7e-05 24.5 1.6 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 KEY64089.1 - 0.0086 16.3 0.7 0.0086 16.3 0.5 3.0 4 0 0 4 4 4 1 bZIP Maf transcription factor zf-C2H2_4 PF13894.1 KEY64089.1 - 0.2 12.0 6.2 1.1 9.7 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger TPR_12 PF13424.1 KEY64090.1 - 5.3e-11 42.3 13.7 1.8e-05 24.5 0.0 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEY64090.1 - 2.6e-10 39.7 0.8 6.9e-07 28.8 0.0 3.4 3 0 0 3 3 3 2 TPR repeat AAA_16 PF13191.1 KEY64090.1 - 4.5e-08 33.3 2.4 3.4e-07 30.4 0.0 3.3 3 0 0 3 3 2 1 AAA ATPase domain TPR_2 PF07719.12 KEY64090.1 - 9e-08 31.4 6.3 0.0068 16.2 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEY64090.1 - 1.1e-06 28.0 2.3 0.0027 17.2 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEY64090.1 - 2.1e-06 27.0 5.5 0.078 12.7 0.0 5.0 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEY64090.1 - 1.1e-05 25.8 0.0 0.0028 18.2 0.0 6.3 5 1 1 6 6 6 2 Tetratricopeptide repeat AAA_10 PF12846.2 KEY64090.1 - 4.7e-05 22.9 0.0 4.7e-05 22.9 0.0 2.6 4 1 0 4 4 4 1 AAA-like domain NACHT PF05729.7 KEY64090.1 - 0.00024 20.7 0.1 0.0058 16.3 0.0 3.0 3 0 0 3 3 2 1 NACHT domain AAA_22 PF13401.1 KEY64090.1 - 0.00062 19.9 0.0 0.0068 16.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain TPR_7 PF13176.1 KEY64090.1 - 0.0023 17.5 1.5 0.32 10.8 0.0 4.5 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEY64090.1 - 0.0041 17.4 10.5 0.097 13.0 0.0 4.7 3 1 1 4 4 4 1 Tetratricopeptide repeat FYVE PF01363.16 KEY64090.1 - 0.027 14.3 4.6 0.057 13.3 3.2 1.5 1 0 0 1 1 1 0 FYVE zinc finger PulS_OutS PF09691.5 KEY64090.1 - 0.049 13.6 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 Bacterial chaperone lipoprotein (PulS_OutS) TPR_6 PF13174.1 KEY64090.1 - 0.065 13.7 4.6 1.5 9.4 0.2 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEY64090.1 - 0.069 13.1 1.0 14 5.7 0.2 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEY64090.1 - 0.81 10.4 14.0 4.5 8.1 0.0 6.2 5 1 1 6 6 5 0 Tetratricopeptide repeat Colipase-like PF15083.1 KEY64091.1 - 0.0012 18.7 4.7 0.04 13.8 0.3 2.1 2 0 0 2 2 2 2 Colipase-like Gamma-thionin PF00304.15 KEY64091.1 - 0.0033 17.4 14.0 0.037 14.0 1.6 2.3 2 0 0 2 2 2 2 Gamma-thionin family WAP PF00095.16 KEY64091.1 - 0.11 12.4 12.9 0.67 9.9 1.4 2.5 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Nodulin_late PF07127.6 KEY64091.1 - 0.55 10.4 3.7 5.8 7.1 0.3 2.3 2 0 0 2 2 2 0 Late nodulin protein Colipase PF01114.13 KEY64091.1 - 1.1 8.8 18.5 0.3 10.6 4.6 2.4 2 0 0 2 2 2 0 Colipase, N-terminal domain Prokineticin PF06607.6 KEY64091.1 - 1.8 8.7 11.1 1.8 8.7 1.4 2.5 2 0 0 2 2 2 0 Prokineticin Abhydrolase_6 PF12697.2 KEY64092.1 - 9.6e-34 117.2 0.6 1.3e-33 116.8 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY64092.1 - 4e-15 55.8 0.1 7.7e-15 54.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY64092.1 - 9.1e-11 41.7 0.1 2.1e-08 34.0 0.0 2.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KEY64092.1 - 0.00037 20.2 0.0 0.0039 17.0 0.0 2.4 1 1 1 2 2 2 1 Putative lysophospholipase Ser_hydrolase PF06821.8 KEY64092.1 - 0.012 15.2 0.1 0.031 13.9 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase SGL PF08450.7 KEY64093.1 - 0.0012 18.2 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Reg_prop PF07494.6 KEY64093.1 - 0.15 12.1 0.2 0.39 10.8 0.1 1.6 1 0 0 1 1 1 0 Two component regulator propeller DUF1921 PF09081.5 KEY64093.1 - 0.22 11.5 1.3 9.5 6.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1921) HET PF06985.6 KEY64096.1 - 2.6e-34 118.3 0.1 4.7e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.8 KEY64096.1 - 0.026 13.4 0.0 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) HECT PF00632.20 KEY64098.1 - 4.3e-77 259.3 0.0 7.5e-77 258.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.17 KEY64098.1 - 0.0053 16.7 7.6 0.36 11.0 0.1 5.3 5 1 1 6 6 6 1 HEAT repeat DUF2246 PF10229.4 KEY64098.1 - 0.064 12.5 1.8 2.1 7.5 0.7 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2246) DUF2013 PF09431.5 KEY64098.1 - 0.081 12.6 0.6 0.25 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2013) RRN3 PF05327.6 KEY64098.1 - 0.13 10.3 18.7 0.014 13.5 9.4 1.9 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 CLASP_N PF12348.3 KEY64098.1 - 0.13 11.5 0.8 0.57 9.4 0.0 2.1 2 0 0 2 2 2 0 CLASP N terminal Arm PF00514.18 KEY64098.1 - 0.33 10.8 12.2 0.36 10.7 0.1 5.3 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat SDA1 PF05285.7 KEY64098.1 - 0.55 9.4 34.4 0.0097 15.2 13.8 2.5 2 0 0 2 2 2 0 SDA1 E1_dh PF00676.15 KEY64099.1 - 3.8e-86 288.5 0.0 4.5e-86 288.2 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KEY64099.1 - 9.2e-05 22.0 0.1 0.0016 18.0 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 KEY64099.1 - 0.011 14.6 0.0 0.045 12.6 0.0 1.8 1 1 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Ubie_methyltran PF01209.13 KEY64100.1 - 1.2e-74 250.3 0.0 3.2e-62 209.6 0.0 2.0 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KEY64100.1 - 6.6e-16 58.2 0.0 9e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY64100.1 - 5.5e-13 49.2 0.0 1.4e-12 47.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY64100.1 - 8e-11 42.2 0.0 1.4e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY64100.1 - 2.7e-10 40.2 0.0 4.4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY64100.1 - 1.1e-09 38.5 0.0 2e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY64100.1 - 2.3e-08 34.6 0.0 4.2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY64100.1 - 7.8e-07 29.1 0.1 1.9e-06 27.8 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KEY64100.1 - 0.019 14.6 0.0 0.072 12.7 0.0 1.9 3 0 0 3 3 3 0 Hypothetical methyltransferase MTS PF05175.9 KEY64100.1 - 0.11 11.9 0.0 0.36 10.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain DUF2433 PF10360.4 KEY64101.1 - 4e-54 182.4 0.0 6.1e-54 181.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 KEY64101.1 - 0.0035 17.1 0.0 0.0085 15.9 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2360 PF10152.4 KEY64101.1 - 0.0039 17.4 12.6 0.035 14.4 8.8 2.3 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) Metallophos PF00149.23 KEY64101.1 - 0.0042 16.5 0.0 0.0096 15.3 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF605 PF04652.11 KEY64101.1 - 3.7 6.8 19.3 5.7 6.2 13.4 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 KEY64101.1 - 6.6 4.8 8.5 8.6 4.4 5.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zds_C PF08632.5 KEY64102.1 - 1.2e-30 104.6 0.5 2e-30 103.9 0.3 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Complex1_30kDa PF00329.14 KEY64103.1 - 1.4e-35 121.6 0.0 2e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.1 KEY64104.1 - 2.7e-19 68.4 12.2 5.6e-19 67.4 8.5 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 KEY64104.1 - 1.2e-07 31.1 0.0 6e-07 29.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY64104.1 - 5.6e-06 26.2 0.0 1.8e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 KEY64104.1 - 1.3e-05 24.7 7.2 1.3e-05 24.7 5.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 KEY64104.1 - 1.5e-05 24.7 0.2 3.7e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 KEY64104.1 - 2.1e-05 23.8 3.5 2.1e-05 23.8 2.5 3.6 3 1 0 3 3 3 1 Rtf2 RING-finger SET_assoc PF11767.3 KEY64104.1 - 0.031 13.5 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Baculo_IE-1 PF05290.6 KEY64104.1 - 0.099 12.3 4.9 0.17 11.5 3.4 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) FYVE_2 PF02318.11 KEY64104.1 - 4.7 7.1 19.8 0.019 14.8 3.0 2.6 1 1 1 2 2 2 0 FYVE-type zinc finger Ion_trans_2 PF07885.11 KEY64105.1 - 4.8e-31 106.3 20.0 5.2e-18 64.5 3.0 3.3 4 0 0 4 4 4 2 Ion channel Filament PF00038.16 KEY64107.1 - 2e-08 34.0 141.8 3.2e-06 26.8 27.6 7.8 1 1 4 6 6 6 3 Intermediate filament protein IncA PF04156.9 KEY64107.1 - 0.0014 18.3 20.5 0.0014 18.3 14.2 9.8 1 1 5 7 7 7 3 IncA protein Reo_sigmaC PF04582.7 KEY64107.1 - 0.0014 17.8 10.1 0.0014 17.8 7.0 8.0 1 1 4 7 7 7 4 Reovirus sigma C capsid protein Spc7 PF08317.6 KEY64107.1 - 0.0019 16.9 10.4 0.0019 16.9 7.2 8.6 1 1 7 10 10 10 5 Spc7 kinetochore protein DUF4201 PF13870.1 KEY64107.1 - 0.0039 16.6 18.0 0.0039 16.6 12.5 9.1 2 1 6 9 9 9 2 Domain of unknown function (DUF4201) AAA_13 PF13166.1 KEY64107.1 - 0.15 10.4 135.8 0.0062 15.0 18.5 6.1 1 1 4 6 6 6 0 AAA domain Pox_A_type_inc PF04508.7 KEY64107.1 - 1.7 8.6 12.0 6.4 6.8 0.1 7.2 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat Baculo_PEP_C PF04513.7 KEY64107.1 - 3.8 7.3 76.8 0.13 12.0 0.5 10.0 3 2 8 11 11 11 0 Baculovirus polyhedron envelope protein, PEP, C terminus PTPA PF03095.10 KEY64109.1 - 2.4e-106 355.3 0.0 2.8e-106 355.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein TFIIA PF03153.8 KEY64110.1 - 4.2 7.1 17.0 5 6.9 11.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit adh_short PF00106.20 KEY64114.1 - 1e-14 54.8 0.3 1.6e-14 54.1 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY64114.1 - 9.8e-05 22.2 0.0 0.00019 21.3 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY64114.1 - 0.00046 19.8 0.2 0.00094 18.8 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY64114.1 - 0.0025 17.2 0.1 0.0068 15.8 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3425 PF11905.3 KEY64115.1 - 4e-26 91.5 0.2 6.5e-26 90.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) COX14 PF14880.1 KEY64116.1 - 0.071 12.7 1.7 5.2 6.7 0.0 3.2 3 0 0 3 3 3 0 Cytochrome oxidase c assembly TRAP-gamma PF07074.7 KEY64116.1 - 2.1 7.8 4.0 0.89 9.0 0.1 2.1 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Velvet PF11754.3 KEY64118.1 - 7.4e-48 162.8 0.9 1.5e-47 161.8 0.2 1.8 2 1 0 2 2 2 1 Velvet factor Acetyltransf_1 PF00583.19 KEY64119.1 - 6.4e-09 35.7 0.0 1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KEY64119.1 - 4e-07 30.1 0.0 9.6e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KEY64119.1 - 3.4e-06 27.1 0.0 5.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEY64119.1 - 0.044 13.5 0.0 0.15 11.8 0.0 1.9 1 1 0 1 1 1 0 FR47-like protein Tim17 PF02466.14 KEY64120.1 - 1.9e-34 118.4 7.9 2.3e-34 118.2 5.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Asparaginase_2 PF01112.13 KEY64121.1 - 1.9e-36 125.4 0.4 2.2e-18 66.0 0.0 3.4 3 0 0 3 3 3 3 Asparaginase bZIP_1 PF00170.16 KEY64121.1 - 4.5e-07 29.7 0.7 1.2e-06 28.3 0.5 1.7 1 0 0 1 1 1 1 bZIP transcription factor CENP-F_leu_zip PF10473.4 KEY64121.1 - 0.059 13.2 0.2 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pkinase PF00069.20 KEY64122.1 - 3.3e-33 114.9 0.0 7.4e-32 110.5 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY64122.1 - 2e-19 69.7 0.0 6.2e-19 68.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase GAS PF13851.1 KEY64122.1 - 0.19 10.9 3.6 0.31 10.2 2.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TSC22 PF01166.13 KEY64122.1 - 0.32 10.9 3.0 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family IncA PF04156.9 KEY64122.1 - 0.62 9.6 3.5 1.5 8.3 2.4 1.6 1 0 0 1 1 1 0 IncA protein DUF4140 PF13600.1 KEY64122.1 - 1 9.8 6.3 3.5 8.1 4.4 1.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) GBP_C PF02841.9 KEY64122.1 - 1.7 7.7 6.4 2.5 7.2 4.4 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Complex1_LYR PF05347.10 KEY64123.1 - 0.00029 20.5 0.0 0.0012 18.6 0.0 2.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KEY64123.1 - 0.00066 19.8 0.0 0.0032 17.6 0.0 2.3 2 0 0 2 2 2 1 Complex1_LYR-like DUF982 PF06169.7 KEY64124.1 - 0.0086 15.7 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF982) DUF3437 PF11919.3 KEY64125.1 - 2e-31 107.5 0.1 7.3e-31 105.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) AP_endonuc_2_N PF07582.7 KEY64125.1 - 0.013 15.0 0.0 0.05 13.1 0.0 2.0 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus HEAT PF02985.17 KEY64125.1 - 0.52 10.5 2.7 21 5.5 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat A_deaminase PF00962.17 KEY64126.1 - 3.2e-41 141.3 0.0 8.6e-41 139.9 0.0 1.6 2 0 0 2 2 2 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 KEY64126.1 - 0.069 13.1 0.4 2.1 8.4 0.0 2.8 2 1 0 2 2 2 0 Adenosine/AMP deaminase N-terminal DUF2207 PF09972.4 KEY64127.1 - 0.53 8.7 1.2 2.7 6.4 0.0 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) SRP40_C PF05022.7 KEY64128.1 - 6.8e-22 77.7 0.6 1.8e-21 76.3 0.4 1.8 1 0 0 1 1 1 1 SRP40, C-terminal domain Rsm1 PF08600.5 KEY64129.1 - 3.4e-26 90.8 3.7 4e-26 90.6 0.1 2.5 2 0 0 2 2 2 1 Rsm1-like zf-C3HC PF07967.8 KEY64129.1 - 1.6e-25 89.3 2.3 2.9e-20 72.4 0.6 3.1 2 1 0 2 2 2 2 C3HC zinc finger-like BIR PF00653.16 KEY64129.1 - 2.9e-05 24.4 0.1 0.0013 19.0 0.0 2.5 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain MMR_HSR1 PF01926.18 KEY64130.1 - 6.4e-17 61.5 0.0 1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KEY64130.1 - 1.9e-07 31.0 0.2 0.00068 19.4 0.2 3.0 2 1 1 3 3 3 2 Dynamin family Miro PF08477.8 KEY64130.1 - 0.00098 19.6 0.0 0.0057 17.1 0.0 2.2 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KEY64130.1 - 0.0011 18.3 0.0 0.0053 16.2 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KEY64130.1 - 0.0034 16.5 0.0 0.0098 15.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Septin PF00735.13 KEY64130.1 - 0.021 13.8 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Septin FeoB_N PF02421.13 KEY64130.1 - 0.021 14.1 0.1 0.065 12.5 0.1 1.8 2 1 0 2 2 2 0 Ferrous iron transport protein B FtsK_SpoIIIE PF01580.13 KEY64130.1 - 0.023 14.1 0.1 0.074 12.5 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.1 KEY64130.1 - 0.024 14.1 0.0 0.23 10.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AIG1 PF04548.11 KEY64130.1 - 0.043 12.9 0.0 0.095 11.7 0.0 1.6 1 1 0 1 1 1 0 AIG1 family zf-CCHC_5 PF14787.1 KEY64130.1 - 0.079 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger IIGP PF05049.8 KEY64130.1 - 0.2 10.4 0.0 0.34 9.6 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) 2OG-FeII_Oxy_2 PF13532.1 KEY64131.1 - 1.1e-32 113.4 0.0 1.5e-32 113.0 0.0 1.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HECT PF00632.20 KEY64132.1 - 5.8e-67 226.0 0.0 6.9e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-C2H2_2 PF12756.2 KEY64134.1 - 5.8e-28 96.9 5.0 1.9e-26 92.1 0.9 3.9 4 0 0 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KEY64134.1 - 2e-06 27.7 24.8 2.4e-05 24.3 2.4 4.6 4 1 1 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEY64134.1 - 1.7e-05 24.8 8.5 6.1e-05 23.0 3.0 3.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type SnoaL_2 PF12680.2 KEY64134.1 - 0.066 13.6 0.3 0.18 12.2 0.1 1.8 2 0 0 2 2 2 0 SnoaL-like domain DUF629 PF04780.7 KEY64134.1 - 5.5 5.3 6.7 0.21 10.1 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF629) EPSP_synthase PF00275.15 KEY64135.1 - 1.1e-126 422.6 0.0 1.5e-125 418.9 0.0 2.2 2 0 0 2 2 2 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 KEY64135.1 - 2.7e-100 334.5 0.0 4.4e-100 333.9 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 KEY64135.1 - 9.5e-63 211.8 0.0 1.5e-62 211.1 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 KEY64135.1 - 2.9e-37 127.9 0.0 9.9e-36 122.9 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 KEY64135.1 - 1.8e-22 79.1 0.0 7.2e-22 77.2 0.0 2.1 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KEY64135.1 - 4.9e-09 36.3 0.0 1.7e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 KEY64135.1 - 4.2e-08 32.8 0.0 1.3e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 KEY64135.1 - 0.0022 18.8 0.0 0.0069 17.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain zf-C2H2 PF00096.21 KEY64136.1 - 6e-10 38.8 12.1 0.014 15.6 0.9 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY64136.1 - 6.9e-07 29.1 13.8 0.003 17.7 0.9 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 KEY64136.1 - 1.1 9.3 5.2 7 6.8 0.8 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Histone PF00125.19 KEY64137.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KEY64137.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KEY64137.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KEY64137.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KEY64137.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KEY64137.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 KEY64138.1 - 3.6e-31 107.0 0.4 5.8e-31 106.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KEY64138.1 - 4.1e-06 26.8 0.0 6.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KEY64138.1 - 0.004 17.1 0.3 0.0074 16.3 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KEY64138.1 - 0.014 15.1 0.1 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated RNA_pol_Rpb1_5 PF04998.12 KEY64139.1 - 1.6e-88 296.6 0.0 3e-88 295.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KEY64139.1 - 1e-63 214.2 0.4 2.3e-63 213.1 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 KEY64139.1 - 1.5e-34 119.7 3.3 8.4e-21 74.5 0.0 2.6 2 1 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 KEY64139.1 - 3.7e-31 107.9 0.0 1.4e-30 106.0 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KEY64139.1 - 2.4e-18 65.8 0.0 1.4e-17 63.3 0.0 2.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 PRP3 PF08572.5 KEY64140.1 - 1.1e-69 234.2 5.3 1.6e-69 233.7 3.7 1.2 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 KEY64140.1 - 1.3e-38 131.5 0.4 1.3e-38 131.5 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Ank_2 PF12796.2 KEY64141.1 - 1.2e-53 179.3 6.5 3.9e-20 71.9 0.1 8.1 3 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KEY64141.1 - 9.4e-36 119.8 16.9 3.5e-08 32.8 0.1 12.1 12 0 0 12 12 12 8 Ankyrin repeat Ank_3 PF13606.1 KEY64141.1 - 1.8e-35 117.3 8.7 3.8e-05 23.5 0.0 13.5 15 0 0 15 15 15 6 Ankyrin repeat Ank_4 PF13637.1 KEY64141.1 - 4.9e-32 109.7 3.6 7.5e-09 35.8 0.1 10.4 7 1 3 10 10 10 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY64141.1 - 5.5e-28 96.3 12.6 8.3e-07 29.0 0.0 11.7 5 3 8 13 13 13 6 Ankyrin repeats (many copies) Clr5 PF14420.1 KEY64141.1 - 0.0074 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Clr5 domain ILVD_EDD PF00920.16 KEY64142.1 - 1.2e-157 525.5 1.2 1.4e-157 525.3 0.9 1.0 1 0 0 1 1 1 1 Dehydratase family ADH_zinc_N PF00107.21 KEY64143.1 - 3.4e-28 97.7 0.2 5.8e-28 97.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY64143.1 - 3.6e-17 62.0 0.0 7.5e-14 51.4 0.0 2.6 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 KEY64143.1 - 0.0018 17.8 0.0 0.0044 16.6 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Shikimate_DH PF01488.15 KEY64143.1 - 0.016 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 KEY64143.1 - 0.036 14.1 0.1 0.06 13.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY64143.1 - 0.059 13.7 0.1 0.62 10.5 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEY64143.1 - 0.099 11.6 0.1 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Glyco_hydro_43 PF04616.9 KEY64146.1 - 9.1e-41 139.8 5.3 1e-40 139.6 3.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 p450 PF00067.17 KEY64147.1 - 7.7e-69 232.3 0.0 9.3e-69 232.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Myosin_tail_1 PF01576.14 KEY64148.1 - 1.6e-05 22.9 37.2 1.6e-05 22.9 25.8 3.4 2 1 1 3 3 3 2 Myosin tail V_ATPase_I PF01496.14 KEY64148.1 - 0.0003 18.8 18.8 0.0003 18.8 13.0 3.8 3 1 0 3 3 3 1 V-type ATPase 116kDa subunit family DUF3584 PF12128.3 KEY64148.1 - 0.0006 17.3 31.0 0.0006 17.3 21.5 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF3584) Fib_alpha PF08702.5 KEY64148.1 - 0.00087 19.4 9.7 0.00087 19.4 6.7 5.7 3 2 2 5 5 5 2 Fibrinogen alpha/beta chain family GAS PF13851.1 KEY64148.1 - 0.002 17.3 24.9 0.002 17.3 17.3 4.9 2 1 3 5 5 5 3 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 KEY64148.1 - 0.0026 16.3 22.6 0.0026 16.3 15.7 4.0 2 1 2 4 4 4 1 AAA domain Reo_sigmaC PF04582.7 KEY64148.1 - 0.004 16.4 6.1 0.004 16.4 4.2 3.9 3 1 1 4 4 4 2 Reovirus sigma C capsid protein Prefoldin PF02996.12 KEY64148.1 - 0.012 15.2 4.1 0.012 15.2 2.8 8.0 3 2 4 7 7 7 0 Prefoldin subunit Trp_DMAT PF11991.3 KEY64150.1 - 4.4e-79 266.2 0.0 5.3e-79 266.0 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Amidohydro_2 PF04909.9 KEY64152.1 - 6.1e-39 134.2 1.7 1.4e-38 133.0 0.4 1.8 1 1 1 2 2 2 1 Amidohydrolase SnoaL_4 PF13577.1 KEY64153.1 - 0.041 13.7 0.0 0.053 13.4 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Abhydrolase_6 PF12697.2 KEY64154.1 - 2.7e-33 115.7 0.0 3.1e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY64154.1 - 8.4e-24 83.9 0.0 3.8e-23 81.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY64154.1 - 2.9e-14 53.1 0.0 1.9e-10 40.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KEY64154.1 - 9.6e-10 38.1 0.1 4.4e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Ser_hydrolase PF06821.8 KEY64154.1 - 3.7e-07 29.9 0.0 0.0021 17.7 0.0 2.2 1 1 1 2 2 2 2 Serine hydrolase Abhydrolase_2 PF02230.11 KEY64154.1 - 0.00011 21.6 0.0 0.51 9.7 0.0 2.7 2 1 0 3 3 3 2 Phospholipase/Carboxylesterase DUF1057 PF06342.7 KEY64154.1 - 0.00013 20.8 0.0 0.00017 20.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Thioesterase PF00975.15 KEY64154.1 - 0.0016 18.6 0.1 0.0028 17.9 0.1 1.6 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 KEY64154.1 - 0.0083 15.7 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KEY64154.1 - 0.01 15.4 0.0 0.027 14.0 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein DLH PF01738.13 KEY64154.1 - 0.017 14.4 0.0 3.6 6.7 0.0 2.7 3 0 0 3 3 3 0 Dienelactone hydrolase family DUF2305 PF10230.4 KEY64154.1 - 0.022 14.2 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Peptidase_S9 PF00326.16 KEY64154.1 - 0.024 13.8 0.0 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Humanin PF15040.1 KEY64154.1 - 0.031 13.5 0.1 0.058 12.6 0.1 1.3 1 0 0 1 1 1 0 Humanin family Abhydrolase_9 PF10081.4 KEY64154.1 - 0.084 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family HTH_29 PF13551.1 KEY64154.1 - 0.14 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Lipase PF00151.14 KEY64154.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipase CoA_transf_3 PF02515.12 KEY64155.1 - 8.5e-30 103.4 0.0 2.2e-29 102.0 0.0 1.6 2 0 0 2 2 2 1 CoA-transferase family III Dioxygenase_C PF00775.16 KEY64156.1 - 1.5e-49 167.7 0.0 2e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KEY64156.1 - 3.3e-12 46.1 0.0 5.1e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KEY64156.1 - 2.2e-05 24.4 0.0 5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 KEY64156.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Cna protein B-type domain DUF2824 PF11039.3 KEY64156.1 - 0.1 12.3 0.0 0.26 10.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2824) DUF4480 PF13715.1 KEY64156.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4480) Aldo_ket_red PF00248.16 KEY64158.1 - 2.6e-37 128.1 0.0 3.2e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Myb_CC_LHEQLE PF14379.1 KEY64158.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif RNR_N PF08343.5 KEY64158.1 - 0.06 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Ribonucleotide reductase N-terminal HTH_8 PF02954.14 KEY64158.1 - 0.098 12.2 0.0 14 5.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family Fungal_trans PF04082.13 KEY64159.1 - 2.9e-15 55.8 0.2 7.8e-15 54.4 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY64159.1 - 0.0026 17.6 7.6 0.0052 16.6 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_10 PF00331.15 KEY64160.1 - 3.6e-99 331.8 0.0 4e-99 331.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF4339 PF14237.1 KEY64160.1 - 0.041 13.4 0.1 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) Cellulase-like PF12876.2 KEY64160.1 - 0.045 14.1 0.1 0.25 11.8 0.0 2.2 3 0 0 3 3 3 0 Sugar-binding cellulase-like COesterase PF00135.23 KEY64161.1 - 1.4e-104 350.7 0.0 1.8e-104 350.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEY64161.1 - 5.3e-06 26.1 0.1 3.9e-05 23.3 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEY64161.1 - 0.00038 19.7 0.0 0.00063 19.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family EKR PF10371.4 KEY64161.1 - 0.085 12.4 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function p450 PF00067.17 KEY64163.1 - 1.3e-77 261.3 0.0 1.7e-77 260.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HeLo PF14479.1 KEY64164.1 - 4.5e-43 147.4 1.2 1e-42 146.3 0.8 1.6 1 0 0 1 1 1 1 Prion-inhibition and propagation FA_desaturase PF00487.19 KEY64164.1 - 4.5e-09 36.1 28.4 9.6e-09 35.0 19.2 1.8 1 1 0 1 1 1 1 Fatty acid desaturase NACHT PF05729.7 KEY64164.1 - 1.9e-06 27.6 0.1 1.1e-05 25.2 0.0 2.3 2 1 0 2 2 2 1 NACHT domain ABC_tran PF00005.22 KEY64164.1 - 0.0037 17.5 0.1 0.013 15.8 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 KEY64164.1 - 0.03 14.4 0.1 0.088 12.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KEY64164.1 - 0.044 12.6 0.0 0.2 10.4 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.1 KEY64164.1 - 0.053 13.0 0.7 0.17 11.4 0.5 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 KEY64164.1 - 0.071 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEY64164.1 - 0.16 12.1 0.1 0.36 11.0 0.1 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 KEY64164.1 - 2.8 7.9 8.4 0.27 11.1 0.3 3.0 4 1 0 4 4 4 0 AAA ATPase domain NmrA PF05368.8 KEY64165.1 - 2.4e-14 53.1 0.1 3.8e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY64165.1 - 1.2e-09 38.4 0.1 1.8e-09 37.9 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KEY64165.1 - 0.0011 18.7 1.3 0.47 10.0 0.1 2.6 2 1 1 3 3 3 2 KR domain Semialdhyde_dh PF01118.19 KEY64165.1 - 0.0048 17.1 0.0 0.014 15.6 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.2 KEY64167.1 - 1.7e-28 100.1 5.2 2.2e-28 99.7 3.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY64167.1 - 1.6e-12 47.4 0.0 3.8e-12 46.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY64167.1 - 1.7e-12 47.3 0.9 1.1e-11 44.7 0.1 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.9 KEY64167.1 - 3.3e-06 25.7 0.0 4.9e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 KEY64167.1 - 7.6e-05 22.4 0.3 0.00017 21.3 0.2 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Lactamase_B PF00753.22 KEY64168.1 - 2e-17 63.5 0.3 3e-17 62.8 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KEY64168.1 - 0.0013 18.2 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Pyr_redox_2 PF07992.9 KEY64169.1 - 3.8e-08 33.4 0.0 1.1e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEY64169.1 - 0.00015 21.5 0.0 0.0039 16.9 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KEY64169.1 - 0.00022 21.3 0.0 0.0071 16.4 0.0 2.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEY64169.1 - 0.0014 17.6 0.4 0.0026 16.7 0.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEY64169.1 - 0.079 11.7 0.2 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KEY64169.1 - 0.088 11.2 0.0 0.27 9.6 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.1 KEY64169.1 - 0.095 12.7 0.1 0.28 11.2 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KEY64169.1 - 0.1 11.5 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Aminotran_1_2 PF00155.16 KEY64169.1 - 0.12 11.2 0.0 0.27 10.1 0.0 1.6 1 0 0 1 1 1 0 Aminotransferase class I and II ThiF PF00899.16 KEY64169.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 ThiF family GIDA PF01134.17 KEY64169.1 - 0.17 10.6 0.1 1 8.1 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A ABC_tran PF00005.22 KEY64170.1 - 8.1e-28 97.4 0.1 1.3e-27 96.7 0.1 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 KEY64170.1 - 1.2e-25 89.9 28.9 2.2e-25 89.0 20.1 1.4 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.1 KEY64170.1 - 5.5e-08 33.1 0.3 0.011 15.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KEY64170.1 - 7.2e-06 25.3 0.0 2.2e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KEY64170.1 - 2.4e-05 24.3 0.5 4.5e-05 23.5 0.1 1.7 2 0 0 2 2 1 1 AAA ATPase domain AAA_25 PF13481.1 KEY64170.1 - 3.4e-05 23.3 0.1 6.4e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KEY64170.1 - 0.00021 20.8 0.0 0.0015 17.9 0.1 2.0 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 KEY64170.1 - 0.00027 20.3 0.2 0.00063 19.2 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KEY64170.1 - 0.00059 20.6 0.1 0.0014 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEY64170.1 - 0.00078 19.5 0.1 0.0018 18.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEY64170.1 - 0.0011 18.6 1.2 0.0038 16.9 0.8 1.9 1 1 0 1 1 1 1 Part of AAA domain DUF258 PF03193.11 KEY64170.1 - 0.0013 17.9 0.1 0.0021 17.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 T2SE PF00437.15 KEY64170.1 - 0.0031 16.4 0.1 0.0055 15.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein IstB_IS21 PF01695.12 KEY64170.1 - 0.0034 16.8 0.2 0.0077 15.6 0.2 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 KEY64170.1 - 0.0052 17.0 0.1 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KEY64170.1 - 0.0052 16.7 0.3 0.0091 15.9 0.2 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KEY64170.1 - 0.0055 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 KEY64170.1 - 0.0074 15.9 0.1 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 NACHT domain cobW PF02492.14 KEY64170.1 - 0.0077 15.6 0.2 0.015 14.7 0.1 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KEY64170.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.5 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KEY64170.1 - 0.015 14.9 0.6 0.027 14.0 0.4 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KEY64170.1 - 0.015 15.5 0.5 0.029 14.6 0.1 1.5 2 0 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KEY64170.1 - 0.016 14.7 0.1 0.026 14.0 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.1 KEY64170.1 - 0.016 15.0 0.1 0.034 14.0 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_15 PF13175.1 KEY64170.1 - 0.017 14.1 0.0 3.6 6.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 KEY64170.1 - 0.025 14.7 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KEY64170.1 - 0.039 14.1 0.0 0.097 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 KEY64170.1 - 0.063 12.9 0.1 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.1 KEY64170.1 - 0.073 12.9 0.0 0.2 11.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain SRP54 PF00448.17 KEY64170.1 - 0.11 11.8 0.3 0.21 10.9 0.2 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain UPF0079 PF02367.12 KEY64170.1 - 0.14 11.8 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 KEY64170.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_5 PF07728.9 KEY64170.1 - 0.16 11.6 0.0 0.65 9.7 0.1 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.12 KEY64170.1 - 0.17 11.3 0.2 0.41 10.1 0.2 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 KEY64170.1 - 0.2 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain p450 PF00067.17 KEY64172.1 - 2.1e-63 214.4 0.0 2.7e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3425 PF11905.3 KEY64173.1 - 4.6e-13 49.2 0.1 8.6e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DivIC PF04977.10 KEY64173.1 - 0.071 12.6 0.1 0.2 11.1 0.1 1.7 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.16 KEY64173.1 - 1.3 9.0 8.5 3.8 7.5 3.3 2.4 2 0 0 2 2 2 0 bZIP transcription factor Zn_clus PF00172.13 KEY64174.1 - 6.2e-05 22.8 8.5 6.2e-05 22.8 5.9 2.2 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PBC PF03792.8 KEY64174.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 PBC domain Abhydrolase_4 PF08386.5 KEY64175.1 - 1.1e-19 70.1 0.0 2.4e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 KEY64175.1 - 3.9e-11 43.2 4.2 3.6e-10 40.1 2.9 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY64175.1 - 1.2e-09 38.0 0.0 2.3e-08 33.8 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY64175.1 - 0.00053 19.7 0.0 0.0085 15.8 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3115 PF11312.3 KEY64176.1 - 3.8e-62 209.9 0.0 4.9e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) DIOX_N PF14226.1 KEY64177.1 - 1.8e-18 67.1 0.0 3.8e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KEY64177.1 - 2.8e-14 53.2 0.0 6.5e-14 52.0 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.13 KEY64178.1 - 2.5e-06 27.2 10.3 4.8e-06 26.3 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.15 KEY64179.1 - 4.4e-50 171.2 2.2 7.3e-50 170.4 1.5 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KEY64179.1 - 2.3e-19 70.4 1.6 5.4e-15 56.1 0.1 3.0 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 KEY64179.1 - 9.1e-17 61.3 0.7 5e-14 52.3 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KEY64179.1 - 9.3e-10 38.1 0.1 4.6e-09 35.9 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase A_deaminase PF00962.17 KEY64179.1 - 1.6e-05 24.0 0.1 0.00024 20.1 0.1 2.3 1 1 0 1 1 1 1 Adenosine/AMP deaminase Xan_ur_permease PF00860.15 KEY64180.1 - 5.3e-48 163.4 29.6 2.1e-47 161.5 20.5 1.7 1 1 0 1 1 1 1 Permease family 4HB_MCP_1 PF12729.2 KEY64180.1 - 0.1 11.9 0.1 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Sugar_tr PF00083.19 KEY64181.1 - 2.9e-117 392.0 17.9 3.3e-117 391.8 12.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY64181.1 - 7.2e-23 80.8 33.3 2.2e-12 46.3 11.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 KEY64181.1 - 0.14 12.1 4.9 0.079 12.9 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) LIF_OSM PF01291.12 KEY64183.1 - 0.045 13.6 0.0 0.058 13.3 0.0 1.2 1 0 0 1 1 1 0 LIF / OSM family zf-CCHC_4 PF14392.1 KEY64185.1 - 0.025 14.2 6.7 0.91 9.2 0.7 2.4 2 0 0 2 2 2 0 Zinc knuckle PEP-utilisers_N PF05524.8 KEY64185.1 - 0.031 14.0 0.1 0.052 13.3 0.1 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal AATase PF07247.7 KEY64186.1 - 2.7e-21 75.6 0.0 1.1e-15 57.2 0.0 2.1 2 0 0 2 2 2 2 Alcohol acetyltransferase Condensation PF00668.15 KEY64186.1 - 1.2e-05 24.3 0.0 2.3e-05 23.4 0.0 1.3 1 1 0 1 1 1 1 Condensation domain Zn_clus PF00172.13 KEY64187.1 - 1.1e-05 25.2 8.3 2.2e-05 24.2 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.22 KEY64188.1 - 5.4e-46 154.2 2.7 1.1e-15 57.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CoA_trans PF01144.18 KEY64190.1 - 8.5e-100 332.3 2.1 3e-58 196.5 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KEY64190.1 - 0.012 15.3 2.1 0.012 15.2 0.1 1.9 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain Methyltransf_16 PF10294.4 KEY64192.1 - 3.1e-18 65.8 0.2 1e-17 64.1 0.1 1.7 1 1 0 1 1 1 1 Putative methyltransferase Helicase_C_2 PF13307.1 KEY64192.1 - 0.086 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Helicase C-terminal domain Fringe PF02434.11 KEY64193.1 - 4.4e-08 32.6 0.0 7.6e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.7 KEY64193.1 - 6.5e-07 28.8 0.2 6.8e-06 25.4 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF604 DUF4283 PF14111.1 KEY64194.1 - 0.094 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) Glyco_hydro_61 PF03443.9 KEY64195.1 - 1e-46 159.5 0.0 1.2e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Peptidase_S10 PF00450.17 KEY64196.1 - 3.9e-77 260.1 1.2 2.5e-76 257.5 0.8 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase Ribonuclease_3 PF00636.21 KEY64198.1 - 3.7e-42 143.3 0.0 2.5e-20 73.0 0.0 3.4 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KEY64198.1 - 2.1e-27 95.6 0.0 8.8e-11 41.8 0.0 3.5 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.9 KEY64198.1 - 9.4e-17 60.5 0.0 3.5e-15 55.5 0.0 2.5 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.26 KEY64198.1 - 1.1e-15 57.2 0.0 3.5e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEY64198.1 - 1.9e-13 50.2 0.0 4.3e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KEY64198.1 - 9.7e-10 38.5 0.0 2.6e-09 37.1 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DSPc PF00782.15 KEY64199.1 - 4.5e-10 39.2 0.2 4.1e-09 36.1 0.0 2.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 KEY64199.1 - 0.018 13.9 0.1 0.14 11.0 0.0 1.9 1 1 1 2 2 2 0 Initiator tRNA phosphoribosyl transferase 7tm_3 PF00003.17 KEY64199.1 - 0.1 11.9 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR DUF572 PF04502.8 KEY64199.1 - 0.22 10.7 6.2 0.38 9.9 4.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) SUV3_C PF12513.3 KEY64200.1 - 4.8e-15 54.7 0.6 9.3e-15 53.8 0.4 1.5 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 KEY64200.1 - 1.6e-07 31.1 0.0 4.4e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEY64200.1 - 0.039 13.4 0.0 0.3 10.5 0.0 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase Synaptobrevin PF00957.16 KEY64201.1 - 2.1e-32 110.5 0.2 2.7e-32 110.1 0.2 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KEY64201.1 - 8.8e-24 82.8 0.0 1.3e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain adh_short PF00106.20 KEY64202.1 - 1.3e-13 51.1 0.0 4.2e-13 49.5 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY64202.1 - 5.6e-07 29.3 0.0 1.3e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KEY64202.1 - 7.8e-06 25.8 0.0 0.00091 19.0 0.0 2.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEY64202.1 - 0.0009 18.7 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY64202.1 - 0.074 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding CP12 PF02672.10 KEY64202.1 - 0.088 13.2 9.1 0.18 12.3 6.3 1.5 1 0 0 1 1 1 0 CP12 domain CENP-I PF07778.6 KEY64202.1 - 4 5.5 5.9 22 3.0 4.2 1.8 2 0 0 2 2 2 0 Mis6 DUF2235 PF09994.4 KEY64203.1 - 3e-104 348.2 2.6 4.1e-104 347.8 1.8 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) ECH PF00378.15 KEY64204.1 - 2.7e-48 164.2 0.0 3.5e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family FLYWCH_N PF15423.1 KEY64205.1 - 0.038 14.1 0.5 0.074 13.2 0.3 1.4 1 0 0 1 1 1 0 FLYWCH-type zinc finger-containing protein PWI PF01480.12 KEY64206.1 - 5.6e-09 35.9 0.1 1.3e-08 34.8 0.1 1.6 1 0 0 1 1 1 1 PWI domain Ribosomal_S21 PF01165.15 KEY64207.1 - 4e-08 32.5 4.3 6.4e-08 31.9 3.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 HAUS6_N PF14661.1 KEY64208.1 - 2.7e-57 193.9 0.5 2.7e-57 193.9 0.3 1.7 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus DUF2617 PF10936.3 KEY64208.1 - 0.076 12.5 0.1 0.42 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF2617 HET PF06985.6 KEY64209.1 - 1.8e-25 89.7 0.9 2.9e-25 89.0 0.7 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PMEI PF04043.10 KEY64209.1 - 0.09 12.6 0.1 0.25 11.2 0.1 1.7 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Coatomer_WDAD PF04053.9 KEY64210.1 - 1.1e-172 574.8 0.0 2.6e-172 573.5 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region Sulfatase PF00884.18 KEY64210.1 - 1e-61 208.8 0.2 2e-61 207.8 0.1 1.5 1 0 0 1 1 1 1 Sulfatase WD40 PF00400.27 KEY64210.1 - 4.3e-44 146.8 8.4 7.6e-10 38.3 0.1 8.0 8 0 0 8 8 8 4 WD domain, G-beta repeat Nup160 PF11715.3 KEY64210.1 - 0.00024 19.3 1.4 0.012 13.8 0.0 3.3 2 2 2 4 4 4 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 KEY64210.1 - 0.0056 16.4 0.0 4.1 7.2 0.0 2.9 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region PGI PF00342.14 KEY64212.1 - 5.4e-208 691.2 0.1 6.2e-208 691.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Mannitol_dh_C PF08125.8 KEY64213.1 - 5.2e-46 156.8 0.1 7.5e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 KEY64213.1 - 3.8e-21 75.6 0.2 5.9e-20 71.7 0.0 2.3 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.9 KEY64213.1 - 0.0014 18.0 0.1 0.0036 16.7 0.1 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 KEY64213.1 - 0.042 13.2 0.0 0.093 12.1 0.0 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 KEY64213.1 - 0.082 13.3 0.3 0.72 10.3 0.2 2.4 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF4440 PF14534.1 KEY64214.1 - 2.4e-09 37.3 0.0 3.1e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF4419 PF14388.1 KEY64215.1 - 5.8e-82 275.2 0.0 6.8e-82 275.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Polysacc_deac_1 PF01522.16 KEY64217.1 - 6.6e-30 103.2 0.1 1.2e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 KEY64217.1 - 9.3e-10 38.3 46.9 9.7e-05 22.2 14.6 2.7 2 1 1 3 3 3 2 Chitin recognition protein MFS_1 PF07690.11 KEY64219.1 - 6.3e-21 74.4 77.3 3.1e-15 55.7 35.0 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.2 KEY64220.1 - 4.8e-05 23.6 0.7 0.00045 20.4 0.5 2.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEY64220.1 - 8.9e-05 22.3 0.3 3.4 8.1 0.1 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KEY64220.1 - 0.00079 19.8 0.4 1.4 9.5 0.1 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY64220.1 - 0.0037 17.4 0.5 0.39 11.0 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 KEY64220.1 - 0.08 12.7 2.3 5.3 7.0 0.2 3.7 4 0 0 4 4 4 0 Ankyrin repeat SHOCT PF09851.4 KEY64220.1 - 0.11 12.0 0.3 0.25 10.8 0.2 1.7 1 0 0 1 1 1 0 Short C-terminal domain Epimerase PF01370.16 KEY64222.1 - 3.9e-17 62.4 0.0 9.9e-17 61.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEY64222.1 - 1.2e-13 50.3 0.0 1.7e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KEY64222.1 - 4.5e-11 43.0 0.0 7e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KEY64222.1 - 3.3e-08 32.7 0.0 5.3e-07 28.8 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KEY64222.1 - 3.3e-07 29.8 1.5 8.3e-07 28.4 1.0 1.6 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KEY64222.1 - 1.7e-05 24.7 4.0 3.5e-05 23.7 0.9 2.5 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY64222.1 - 0.00084 19.0 0.8 0.0038 16.8 0.5 2.0 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KEY64222.1 - 0.0024 16.8 0.1 0.0039 16.1 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ImcF-related_N PF14331.1 KEY64223.1 - 0.012 14.5 0.1 0.014 14.3 0.1 1.1 1 0 0 1 1 1 0 ImcF-related N-terminal domain Sec2p PF06428.6 KEY64223.1 - 0.47 10.3 4.0 0.45 10.3 1.7 1.8 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF4200 PF13863.1 KEY64223.1 - 1.5 8.7 5.5 1 9.3 1.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) G_glu_transpept PF01019.16 KEY64224.1 - 1.1e-158 528.9 0.2 1.2e-158 528.7 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Pectate_lyase PF03211.8 KEY64226.1 - 1.2e-48 165.3 0.4 1.8e-48 164.8 0.3 1.1 1 0 0 1 1 1 1 Pectate lyase Zn_clus PF00172.13 KEY64227.1 - 4.4e-07 29.6 11.0 7.8e-07 28.8 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KEY64228.1 - 1.5e-30 106.2 0.0 2.5e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY64228.1 - 2.1e-20 72.9 0.0 3.4e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HET PF06985.6 KEY64228.1 - 4.9e-15 55.9 0.0 1.2e-14 54.6 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 KEY64229.1 - 3e-15 56.0 0.0 6e-15 55.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Acyl_transf_3 PF01757.17 KEY64230.1 - 7e-34 117.1 17.4 1.2e-33 116.4 12.1 1.4 1 0 0 1 1 1 1 Acyltransferase family CReP_N PF10472.4 KEY64230.1 - 0.0052 15.5 0.2 0.0076 15.0 0.1 1.1 1 0 0 1 1 1 1 eIF2-alpha phosphatase phosphorylation constitutive repressor DUF1768 PF08719.6 KEY64231.1 - 9.9e-48 161.8 0.1 1.2e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Nol1_Nop2_Fmu PF01189.12 KEY64232.1 - 1e-18 67.7 0.0 2.4e-13 50.1 0.0 2.3 2 0 0 2 2 2 2 NOL1/NOP2/sun family Nop14 PF04147.7 KEY64232.1 - 1.2 7.0 8.0 0.11 10.4 2.7 1.5 2 0 0 2 2 2 0 Nop14-like family PBP1_TM PF14812.1 KEY64232.1 - 3 8.1 14.9 4.8 7.5 0.3 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1996 PF09362.5 KEY64233.1 - 6.9e-66 222.2 0.1 9.1e-66 221.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Metallophos PF00149.23 KEY64234.1 - 4.3e-10 39.3 0.0 1.6e-09 37.4 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEY64234.1 - 8.4e-06 25.7 0.0 1.6e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Velvet PF11754.3 KEY64235.1 - 1.3e-48 165.2 0.0 4.9e-48 163.4 0.0 1.8 1 1 1 2 2 2 1 Velvet factor Cellulase PF00150.13 KEY64236.1 - 6.5e-21 74.7 0.2 9e-21 74.3 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KEY64236.1 - 4.5e-11 42.2 8.6 9.9e-11 41.1 6.0 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Cellulase-like PF12876.2 KEY64236.1 - 4e-05 23.9 0.0 8.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 KEY64236.1 - 0.0086 15.0 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 KEY64236.1 - 0.02 14.0 0.0 0.051 12.6 0.0 1.6 2 0 0 2 2 2 0 Beta-galactosidase CbbQ_C PF08406.5 KEY64237.1 - 0.017 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal MCRS_N PF13325.1 KEY64237.1 - 0.037 13.5 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 N-terminal region of micro-spherule protein NGP1NT PF08153.7 KEY64238.1 - 2.2e-48 163.4 0.6 3.4e-48 162.8 0.4 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 KEY64238.1 - 4e-19 68.6 0.0 1.5e-14 53.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 KEY64238.1 - 1.1e-06 28.5 0.6 0.011 15.5 0.1 3.5 2 1 1 3 3 3 2 Dynamin family FeoB_N PF02421.13 KEY64238.1 - 1.5e-05 24.2 0.0 0.00013 21.2 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 KEY64238.1 - 0.00069 18.9 0.0 0.66 9.1 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEY64238.1 - 0.00082 18.8 0.1 0.2 11.0 0.0 3.1 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KEY64238.1 - 0.0014 19.1 0.3 0.43 11.0 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 KEY64238.1 - 0.0063 15.7 0.0 0.015 14.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KEY64238.1 - 0.018 14.1 0.1 0.071 12.2 0.0 2.0 2 0 0 2 2 2 0 AIG1 family DUF3306 PF11748.3 KEY64239.1 - 0.14 12.8 2.6 0.3 11.7 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) ABC2_membrane PF01061.19 KEY64240.1 - 4.3e-36 124.0 18.9 4.3e-36 124.0 13.1 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 KEY64240.1 - 6.8e-25 87.9 0.1 1.8e-24 86.5 0.0 1.8 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 KEY64240.1 - 1.7e-09 38.1 0.0 7.1e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 KEY64240.1 - 6.5e-05 22.1 14.7 6.5e-05 22.1 10.2 2.4 1 1 0 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.1 KEY64240.1 - 6.8e-05 22.3 0.0 0.011 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain hEGF PF12661.2 KEY64240.1 - 8.1e-05 22.4 19.4 0.005 16.8 2.4 4.2 3 0 0 3 3 3 2 Human growth factor-like EGF AAA_29 PF13555.1 KEY64240.1 - 0.0027 17.1 0.1 0.0065 15.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KEY64240.1 - 0.009 15.2 0.0 0.023 13.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 KEY64240.1 - 0.016 14.2 0.0 2.1 7.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 KEY64240.1 - 0.024 14.9 0.0 0.047 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KEY64240.1 - 0.029 14.5 0.0 0.069 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 KEY64240.1 - 0.05 12.8 0.0 0.37 9.9 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 KEY64240.1 - 0.053 13.1 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 KEY64240.1 - 0.067 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 KEY64240.1 - 0.092 13.5 0.0 0.19 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KEY64240.1 - 0.1 12.9 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KEY64240.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Glyco_transf_90 PF05686.7 KEY64242.1 - 3.6e-06 25.9 0.2 0.0066 15.1 0.0 3.2 3 1 0 3 3 3 2 Glycosyl transferase family 90 zf-DHHC PF01529.15 KEY64243.1 - 1.4e-28 99.4 7.4 3.4e-28 98.2 5.1 1.7 1 1 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 KEY64243.1 - 0.092 12.5 0.5 0.22 11.3 0.3 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily Myosin_head PF00063.16 KEY64244.1 - 1.5e-233 776.8 2.2 2.3e-233 776.2 1.5 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KEY64244.1 - 3.1e-41 140.8 0.0 7.5e-41 139.6 0.0 1.7 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 KEY64244.1 - 1e-11 44.0 0.1 2e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KEY64244.1 - 4.2e-10 39.0 0.1 1.1e-09 37.6 0.0 1.8 2 0 0 2 2 1 1 Variant SH3 domain SH3_2 PF07653.12 KEY64244.1 - 4.1e-07 29.3 0.0 2.1e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain IQ PF00612.22 KEY64244.1 - 0.0015 17.9 9.7 0.041 13.5 1.7 2.7 1 1 1 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 KEY64244.1 - 0.0048 17.0 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEY64244.1 - 0.02 14.0 0.0 0.053 12.6 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin Hpr_kinase_C PF07475.7 KEY64244.1 - 0.023 13.9 0.7 3 7.1 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain DUF552 PF04472.7 KEY64244.1 - 0.038 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF552) AAA_17 PF13207.1 KEY64244.1 - 0.059 14.2 0.0 0.21 12.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEY64244.1 - 0.076 13.3 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KEY64244.1 - 0.085 12.5 0.1 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain RPEL PF02755.10 KEY64245.1 - 3.7e-20 70.6 5.3 5.1e-10 38.3 0.1 2.4 2 0 0 2 2 2 2 RPEL repeat MEA1 PF06910.6 KEY64245.1 - 0.0051 16.4 0.3 0.0069 16.0 0.2 1.3 1 0 0 1 1 1 1 Male enhanced antigen 1 (MEA1) DUF2880 PF11082.3 KEY64245.1 - 0.089 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2880) FKBP_C PF00254.23 KEY64247.1 - 1.8e-35 120.7 0.0 2.8e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MT0933_antitox PF14013.1 KEY64247.1 - 0.0005 20.1 1.1 0.001 19.1 0.8 1.5 1 0 0 1 1 1 1 MT0933-like antitoxin protein DUF745 PF05335.8 KEY64247.1 - 0.0071 15.8 7.6 0.011 15.2 5.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF745) TrkH PF02386.11 KEY64248.1 - 2.3e-91 306.0 13.2 1.3e-86 290.4 4.8 2.1 2 0 0 2 2 2 2 Cation transport protein IMS PF00817.15 KEY64249.1 - 2.8e-43 147.2 0.4 2.8e-43 147.2 0.3 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 KEY64249.1 - 1.1e-16 60.9 0.0 2.6e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KEY64249.1 - 0.0035 17.2 0.0 0.011 15.7 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif zf-RanBP PF00641.13 KEY64249.1 - 1.7 7.7 4.5 1.2 8.2 0.5 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Protocadherin PF08374.6 KEY64251.1 - 0.014 15.0 0.0 0.042 13.4 0.0 1.8 1 0 0 1 1 1 0 Protocadherin Zip PF02535.17 KEY64251.1 - 0.021 13.8 0.5 0.081 11.9 0.3 1.9 1 1 0 1 1 1 0 ZIP Zinc transporter Herpes_gE PF02480.11 KEY64251.1 - 0.062 11.5 0.0 0.13 10.4 0.0 1.5 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 KEY64251.1 - 0.14 12.5 1.8 0.14 12.5 0.1 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 KEY64251.1 - 0.36 10.9 0.0 0.36 10.9 0.0 2.1 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator DUF4446 PF14584.1 KEY64251.1 - 0.61 9.9 3.7 13 5.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Ctr PF04145.10 KEY64251.1 - 1.4 8.9 0.0 1.4 8.9 0.0 2.4 2 1 0 2 2 2 0 Ctr copper transporter family Mnd1 PF03962.10 KEY64251.1 - 2.2 7.9 7.1 3.9 7.0 4.9 1.3 1 0 0 1 1 1 0 Mnd1 family IncA PF04156.9 KEY64251.1 - 3.9 7.0 9.5 49 3.4 6.9 1.9 2 0 0 2 2 2 0 IncA protein FixQ PF05545.6 KEY64251.1 - 5.2 6.8 6.0 0.46 10.1 0.6 1.9 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ RCR PF12273.3 KEY64251.1 - 9 6.8 8.1 0.74 10.3 0.4 2.8 2 2 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Flavodoxin_1 PF00258.20 KEY64252.1 - 3.7e-09 36.7 0.0 5.6e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 KEY64252.1 - 1.7e-07 30.8 0.0 2.2e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KEY64252.1 - 2.1e-05 24.1 0.0 2.4e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold DUF3995 PF13160.1 KEY64253.1 - 5.6 7.0 14.0 0.41 10.6 2.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3995) F-box PF00646.28 KEY64254.1 - 0.0035 16.9 0.0 0.014 15.0 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KEY64254.1 - 0.0098 15.6 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 KEY64254.1 - 0.079 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 PRANC domain SET PF00856.23 KEY64255.1 - 2.1e-07 31.4 0.0 6.5e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 SET domain WD40 PF00400.27 KEY64256.1 - 8.5e-42 139.5 14.2 7.2e-10 38.3 0.2 7.4 7 1 0 7 7 7 6 WD domain, G-beta repeat Cornichon PF03311.9 KEY64257.1 - 1.6e-53 180.2 11.1 1.8e-53 180.0 7.7 1.0 1 0 0 1 1 1 1 Cornichon protein Prenyltransf PF01255.14 KEY64258.1 - 0.066 12.3 0.1 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase RRM_1 PF00076.17 KEY64259.1 - 2.2e-83 273.8 8.2 2.9e-22 78.0 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY64259.1 - 4.6e-55 183.5 2.2 2.6e-16 59.3 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY64259.1 - 4.1e-41 138.6 0.3 3.6e-10 39.5 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KEY64259.1 - 1.2e-29 101.7 1.0 5.2e-29 99.7 0.6 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 KEY64259.1 - 3.9e-05 23.3 0.2 3.2 7.5 0.0 4.8 4 1 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KEY64259.1 - 0.0038 16.9 2.5 1.7 8.4 0.1 3.4 3 0 0 3 3 3 1 Limkain b1 CbiG_mid PF11761.3 KEY64259.1 - 0.0052 16.9 0.3 4 7.7 0.0 3.8 3 1 1 4 4 4 1 Cobalamin biosynthesis central region PAT1 PF09770.4 KEY64259.1 - 0.0084 14.4 19.9 0.012 13.8 13.8 1.3 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 YflT PF11181.3 KEY64259.1 - 0.0086 16.2 6.8 0.23 11.6 0.6 3.4 3 0 0 3 3 3 1 Heat induced stress protein YflT TC1 PF15063.1 KEY64259.1 - 0.038 13.5 0.6 14 5.2 0.0 3.0 3 0 0 3 3 3 0 Thyroid cancer protein 1 OB_RNB PF08206.6 KEY64259.1 - 0.053 13.0 2.3 6.2 6.4 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain HECT PF00632.20 KEY64260.1 - 4.3e-80 269.2 0.0 6.6e-80 268.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 KEY64260.1 - 0.00037 19.8 3.0 0.00095 18.6 2.0 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Glyco_hydro_92 PF07971.7 KEY64261.1 - 5.5e-166 553.1 0.0 6.9e-166 552.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Mpp10 PF04006.7 KEY64262.1 - 6.8e-88 295.5 56.3 1.4e-86 291.1 39.0 2.1 1 1 0 1 1 1 1 Mpp10 protein Methyltransf_16 PF10294.4 KEY64262.1 - 4.2e-16 58.8 0.0 7.4e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KEY64262.1 - 1.8e-11 44.5 0.0 6e-11 42.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY64262.1 - 3e-05 24.0 0.3 7.7e-05 22.7 0.2 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY64262.1 - 0.00014 22.2 0.0 0.00046 20.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY64262.1 - 0.00035 19.9 0.0 0.0038 16.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.7 KEY64262.1 - 0.00057 19.4 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_31 PF13847.1 KEY64262.1 - 0.0029 17.2 0.0 0.0062 16.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KEY64262.1 - 0.045 13.2 0.0 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SHNi-TPR PF10516.4 KEY64263.1 - 3.3e-09 35.8 0.1 1e-08 34.2 0.1 1.9 1 0 0 1 1 1 1 SHNi-TPR TPR_12 PF13424.1 KEY64263.1 - 1.5e-05 24.8 4.3 0.075 12.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEY64263.1 - 3.8e-05 23.2 2.1 0.0066 16.0 0.0 3.2 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.1 KEY64263.1 - 6e-05 23.5 0.6 0.00027 21.5 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEY64263.1 - 0.012 15.4 4.3 1.1 9.4 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.7 KEY64263.1 - 0.031 14.0 1.6 0.06 13.1 0.4 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat CHDCT2 PF08074.6 KEY64263.1 - 0.67 9.6 3.0 2.1 8.0 0.2 2.5 2 1 0 2 2 2 0 CHDCT2 (NUC038) domain Glyoxalase_2 PF12681.2 KEY64264.1 - 4.2e-07 30.5 0.0 1.6e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase PF00903.20 KEY64264.1 - 0.0035 17.2 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DHquinase_I PF01487.10 KEY64265.1 - 2.4e-57 194.1 0.0 3.6e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Cyclin PF08613.6 KEY64266.1 - 8.2e-14 52.2 0.0 1.3e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KEY64266.1 - 0.00015 21.3 0.1 0.00024 20.6 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ank_2 PF12796.2 KEY64267.1 - 6.2e-97 318.1 30.7 3e-11 43.4 0.0 18.3 6 5 12 18 18 18 17 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEY64267.1 - 1.6e-75 248.2 40.4 2.1e-08 34.4 0.0 21.0 17 4 5 22 22 21 16 Ankyrin repeats (many copies) Ank PF00023.25 KEY64267.1 - 9.5e-69 223.9 45.1 1.5e-06 27.6 0.0 28.3 29 3 0 29 29 29 15 Ankyrin repeat Ank_5 PF13857.1 KEY64267.1 - 4e-61 201.6 53.5 3.1e-07 30.4 0.0 22.3 20 3 2 23 23 23 16 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY64267.1 - 1.5e-50 164.1 37.7 0.00024 21.0 0.0 26.1 30 0 0 30 30 28 10 Ankyrin repeat NACHT PF05729.7 KEY64267.1 - 8.5e-09 35.2 0.1 3.4e-08 33.3 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEY64267.1 - 5.1e-05 23.3 0.0 0.00023 21.2 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 KEY64267.1 - 0.0034 17.0 0.0 0.04 13.6 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 KEY64267.1 - 0.022 14.8 0.2 0.2 11.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain ResIII PF04851.10 KEY64267.1 - 0.042 13.6 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KEY64267.1 - 0.057 12.3 0.0 0.099 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) LVIVD PF08309.6 KEY64268.1 - 0.004 16.1 0.0 5.3 6.1 0.0 3.9 3 0 0 3 3 3 2 LVIVD repeat DUF2461 PF09365.5 KEY64269.1 - 0.088 12.1 4.6 0.21 10.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) KAR9 PF08580.5 KEY64269.1 - 3.4 5.8 6.1 4.8 5.3 4.2 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 phiKZ_IP PF12699.2 KEY64269.1 - 4.7 6.0 6.6 7.2 5.4 4.6 1.2 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins PsbX PF06596.6 KEY64270.1 - 3.2 7.4 4.8 82 3.0 3.3 2.4 1 1 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) SAM_2 PF07647.12 KEY64271.1 - 1.1e-16 60.4 0.0 2.9e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KEY64271.1 - 1.1e-14 54.2 0.0 2.3e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 KEY64271.1 - 2.5e-14 53.5 0.0 4.9e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Aminotran_1_2 PF00155.16 KEY64272.1 - 2.1e-58 198.0 0.0 2.8e-58 197.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KEY64272.1 - 0.0022 17.1 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KEY64272.1 - 0.18 10.0 0.0 0.28 9.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KEY64272.1 - 0.2 10.3 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KEY64272.1 - 0.22 10.5 0.0 0.49 9.3 0.0 1.5 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family AMP-binding PF00501.23 KEY64273.1 - 1.2e-52 178.7 0.0 1.5e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEY64273.1 - 4.7e-06 27.4 0.0 1.8e-05 25.5 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain WD40 PF00400.27 KEY64274.1 - 2.5e-48 160.2 20.5 9.1e-10 38.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KEY64274.1 - 0.00019 21.2 0.0 0.095 12.3 0.0 2.5 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Phosducin PF02114.11 KEY64275.1 - 3.7e-11 42.2 0.1 3.1e-10 39.2 0.1 2.1 1 1 0 1 1 1 1 Phosducin GATA PF00320.22 KEY64276.1 - 7.4e-15 54.0 3.4 1.3e-14 53.2 2.4 1.4 1 0 0 1 1 1 1 GATA zinc finger MIF4G PF02854.14 KEY64277.1 - 5.5e-52 176.2 0.0 1.1e-51 175.2 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 KEY64277.1 - 2.9e-20 71.9 0.6 2.9e-20 71.9 0.4 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor 4G1 DNA_pol_B PF00136.16 KEY64278.1 - 5.4e-112 374.9 0.5 8.8e-112 374.2 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 KEY64278.1 - 2.9e-65 219.1 0.0 5.6e-65 218.2 0.0 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 KEY64278.1 - 8.3e-41 139.8 0.0 1.4e-40 139.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 KEY64278.1 - 2.6e-23 81.6 8.7 2.6e-23 81.6 6.1 3.1 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal TF_Zn_Ribbon PF08271.7 KEY64278.1 - 0.17 11.2 0.3 0.67 9.3 0.1 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding PPR_2 PF13041.1 KEY64279.1 - 9.9e-23 79.8 3.2 2e-15 56.4 0.2 3.3 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.15 KEY64279.1 - 1.9e-07 30.5 1.1 0.012 15.4 0.1 4.3 4 0 0 4 4 4 2 PPR repeat PPR_1 PF12854.2 KEY64279.1 - 3.7e-07 29.5 0.0 0.32 10.4 0.0 4.3 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.1 KEY64279.1 - 4.4e-07 29.6 6.9 0.11 12.8 0.0 5.4 6 0 0 6 6 6 3 Pentatricopeptide repeat domain ATP13 PF12921.2 KEY64279.1 - 0.027 13.7 2.3 0.19 11.0 0.0 3.2 4 0 0 4 4 4 0 Mitochondrial ATPase expression Drf_FH3 PF06367.11 KEY64279.1 - 0.072 12.4 1.4 5.5 6.3 0.0 3.1 3 0 0 3 3 3 0 Diaphanous FH3 Domain Btz PF09405.5 KEY64280.1 - 0.003 17.6 0.1 0.0051 16.8 0.1 1.4 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding Pkinase PF00069.20 KEY64281.1 - 4e-53 180.2 0.0 9.7e-53 178.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY64281.1 - 3.2e-23 82.1 0.0 3.2e-23 82.1 0.0 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.18 KEY64281.1 - 0.00017 21.3 0.4 0.0005 19.8 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KEY64281.1 - 0.0032 16.8 0.2 0.01 15.1 0.1 1.7 1 1 0 1 1 1 1 RIO1 family Tom5 PF10642.4 KEY64281.1 - 4.1 7.1 7.7 11 5.8 5.3 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase RRM_1 PF00076.17 KEY64282.1 - 1.7e-59 197.3 0.0 3.2e-21 74.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY64282.1 - 1.3e-42 143.6 0.1 3.8e-14 52.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY64282.1 - 8e-31 105.6 0.0 5.6e-11 42.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEY64282.1 - 1.4e-06 27.9 0.0 0.013 15.2 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 KEY64282.1 - 0.00016 21.5 0.0 0.77 9.7 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_3 PF08777.6 KEY64282.1 - 0.13 12.1 0.0 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif Med2 PF11214.3 KEY64283.1 - 0.00092 19.2 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 2 Herpes_UL25 PF01499.11 KEY64283.1 - 0.058 11.6 0.4 0.091 11.0 0.3 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family Cellulase PF00150.13 KEY64284.1 - 1.3e-18 67.1 0.1 2.2e-18 66.4 0.1 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) B12-binding PF02310.14 KEY64284.1 - 0.0016 18.2 0.0 0.018 14.9 0.0 2.2 2 0 0 2 2 2 1 B12 binding domain PH PF00169.24 KEY64285.1 - 3.3e-25 88.2 0.9 2.6e-13 50.0 0.2 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KEY64285.1 - 8.1e-09 35.7 3.7 0.00015 21.9 0.1 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 KEY64285.1 - 2.3e-08 34.2 1.5 0.00028 21.0 0.6 3.3 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 KEY64285.1 - 0.0002 21.3 0.2 0.00037 20.5 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Rota_VP2 PF05087.7 KEY64285.1 - 0.22 9.4 0.2 0.3 8.9 0.1 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein APH PF01636.18 KEY64286.1 - 5.7e-13 49.1 0.1 8e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEY64286.1 - 0.00076 19.1 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 KEY64286.1 - 0.0048 16.0 0.0 0.007 15.5 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 KEY64286.1 - 0.022 13.4 0.0 0.03 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF2392 PF10288.4 KEY64287.1 - 7.4e-17 61.6 0.0 5e-16 58.9 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) DUF1289 PF06945.8 KEY64287.1 - 0.094 12.1 0.1 0.28 10.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) Mito_carr PF00153.22 KEY64288.1 - 2.5e-60 200.2 3.7 5.5e-20 70.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 KEY64289.1 - 1e-20 72.7 0.7 3.6e-11 42.5 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KEY64289.1 - 0.011 14.4 0.3 0.25 10.0 0.2 2.1 1 1 1 2 2 2 0 Nup133 N terminal like SRP9-21 PF05486.7 KEY64290.1 - 2.7e-26 91.1 0.0 3.4e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Ribonuc_red_sm PF00268.16 KEY64291.1 - 3.1e-119 397.1 1.8 4.1e-119 396.7 1.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4112 PF13430.1 KEY64292.1 - 2.2e-33 114.3 0.5 2.9e-33 113.9 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DCP2 PF05026.8 KEY64293.1 - 8.9e-36 121.6 1.1 8.9e-36 121.6 0.8 1.9 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.23 KEY64293.1 - 1.9e-17 63.1 0.0 3.7e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain BC10 PF06726.7 KEY64295.1 - 0.087 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Bladder cancer-related protein BC10 Pkinase PF00069.20 KEY64296.1 - 1.6e-59 201.1 0.0 2.1e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY64296.1 - 3.5e-27 95.1 0.0 5e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY64296.1 - 0.0035 16.3 0.0 0.0058 15.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEY64296.1 - 0.014 15.1 0.0 0.014 15.1 0.0 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KEY64296.1 - 0.018 14.1 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_28 PF02636.12 KEY64297.1 - 5e-82 275.0 0.0 6.2e-82 274.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Lung_7-TM_R PF06814.8 KEY64298.1 - 3.3e-70 236.3 15.6 4e-70 236.0 10.8 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF2648 PF10855.3 KEY64298.1 - 0.67 9.4 2.9 13 5.3 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2648) DUF1980 PF09323.5 KEY64298.1 - 6.1 6.5 6.7 0.4 10.3 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) PrgI PF12666.2 KEY64298.1 - 8.7 6.5 23.0 0.64 10.1 0.5 3.8 1 1 3 4 4 4 0 PrgI family protein Pro_isomerase PF00160.16 KEY64299.1 - 3e-47 160.7 0.0 5.9e-47 159.7 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 KEY64299.1 - 1.8e-05 24.6 0.1 0.00018 21.3 0.0 2.5 2 0 0 2 2 2 1 U-box domain Fungal_trans_2 PF11951.3 KEY64300.1 - 1.7e-08 33.5 0.5 2.9e-06 26.1 0.2 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY64300.1 - 7.6e-08 32.1 11.4 1.8e-07 30.9 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_16 PF00722.16 KEY64301.1 - 3.4e-12 46.0 0.0 6.4e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fungal_trans PF04082.13 KEY64302.1 - 5.2e-16 58.3 2.0 8.8e-16 57.5 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 KEY64302.1 - 2.7e-08 33.7 12.5 1.7e-05 24.8 4.1 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KEY64302.1 - 5.9e-05 23.1 13.0 0.0041 17.3 3.6 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY64302.1 - 0.00023 21.3 14.7 0.035 14.4 4.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type RasGEF PF00617.14 KEY64303.1 - 6.2e-63 211.9 0.2 1.1e-62 211.0 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KEY64303.1 - 1.9e-28 98.6 1.4 5.3e-28 97.1 0.6 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.23 KEY64303.1 - 5.8e-16 57.6 0.1 1.3e-15 56.5 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KEY64303.1 - 2.2e-14 52.7 0.2 5.9e-14 51.3 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KEY64303.1 - 1.3e-13 50.1 0.4 8.8e-13 47.5 0.0 2.5 3 0 0 3 3 3 1 Variant SH3 domain WW PF00397.21 KEY64303.1 - 0.058 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 WW domain Lipase_GDSL_2 PF13472.1 KEY64305.1 - 4.6e-15 56.2 0.0 8.9e-14 52.0 0.0 2.2 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase family IATP PF04568.7 KEY64306.1 - 0.026 14.5 1.3 0.034 14.1 0.9 1.2 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF106 PF01956.11 KEY64306.1 - 0.035 13.6 1.4 0.039 13.4 1.0 1.0 1 0 0 1 1 1 0 Integral membrane protein DUF106 Fungal_trans_2 PF11951.3 KEY64308.1 - 1.9e-07 30.0 0.0 5.2e-07 28.5 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain SCA7 PF08313.7 KEY64309.1 - 2e-34 116.9 0.6 6.1e-34 115.4 0.4 1.8 1 0 0 1 1 1 1 SCA7, zinc-binding domain Menin PF05053.8 KEY64309.1 - 7.1 4.6 9.7 9.6 4.2 6.7 1.2 1 0 0 1 1 1 0 Menin Mito_carr PF00153.22 KEY64310.1 - 3.7e-47 157.9 0.5 7e-17 60.9 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C3HC4_2 PF13923.1 KEY64311.1 - 1.8e-09 37.4 12.5 4e-05 23.5 2.8 2.7 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY64311.1 - 1.6e-05 24.5 4.3 1.6e-05 24.5 3.0 3.1 2 2 0 2 2 2 1 zinc-RING finger domain Rtf2 PF04641.7 KEY64311.1 - 3.5e-05 23.1 1.3 3.5e-05 23.1 0.9 2.5 2 1 1 3 3 3 1 Rtf2 RING-finger zf-C3HC4_3 PF13920.1 KEY64311.1 - 4.4e-05 23.0 18.1 0.00041 19.9 4.2 3.2 2 1 1 3 3 3 3 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEY64311.1 - 0.0001 21.8 1.2 0.0001 21.8 0.9 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEY64311.1 - 0.00021 21.0 16.9 0.0043 16.8 4.6 2.8 2 1 0 2 2 2 2 Ring finger domain zf-RING_UBOX PF13445.1 KEY64311.1 - 0.00027 20.5 4.2 0.00027 20.5 2.9 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KEY64311.1 - 0.0015 18.3 13.7 0.04 13.8 4.4 2.6 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING FYVE PF01363.16 KEY64311.1 - 0.0063 16.3 7.7 0.0078 16.0 1.1 2.7 2 0 0 2 2 2 1 FYVE zinc finger Acyltransferase PF01553.16 KEY64312.1 - 2.5e-11 43.1 0.0 4.1e-10 39.1 0.0 2.1 1 1 0 1 1 1 1 Acyltransferase Pkinase PF00069.20 KEY64313.1 - 6.8e-78 261.3 0.0 8.3e-78 261.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY64313.1 - 1.2e-38 132.6 0.0 1.8e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY64313.1 - 0.0069 15.3 0.0 0.025 13.5 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEY64313.1 - 0.055 12.5 0.8 0.085 11.9 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEY64313.1 - 0.13 12.0 1.9 0.2 11.3 0.0 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family Septin PF00735.13 KEY64314.1 - 6.7e-08 31.8 0.0 1.1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Septin DUF2366 PF10171.4 KEY64314.1 - 0.07 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2366) AhpC-TSA_2 PF13911.1 KEY64315.1 - 1.1e-13 51.1 0.0 1.5e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KEY64315.1 - 0.00017 21.2 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Tubulin_3 PF14881.1 KEY64316.1 - 2.6e-76 255.1 0.0 1.9e-75 252.2 0.0 2.0 2 0 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.4 KEY64316.1 - 6.8e-39 132.4 0.1 2.4e-38 130.7 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 KEY64316.1 - 7.3e-08 32.4 0.0 0.00016 21.6 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain PAP_central PF04928.12 KEY64317.1 - 4e-102 340.3 0.0 5.3e-102 339.9 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KEY64317.1 - 9.3e-46 155.2 0.6 2.5e-45 153.8 0.1 1.9 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KEY64317.1 - 1.1e-07 32.0 0.1 2.8e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Peptidase_S49 PF01343.13 KEY64317.1 - 0.041 13.6 0.3 0.088 12.5 0.0 1.6 2 0 0 2 2 2 0 Peptidase family S49 DUF2423 PF10338.4 KEY64318.1 - 1.7e-16 59.8 5.8 1.7e-16 59.8 4.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) PDCD2_C PF04194.8 KEY64318.1 - 0.22 11.1 1.5 0.31 10.6 1.1 1.3 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain Fork_head PF00250.13 KEY64319.1 - 8.9e-35 118.6 0.3 1.7e-34 117.7 0.2 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KEY64319.1 - 2.8e-10 40.1 0.1 9.4e-10 38.4 0.0 1.9 2 0 0 2 2 2 1 FHA domain CLU PF13236.1 KEY64320.1 - 2.9e-81 272.1 0.0 4.4e-81 271.5 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 KEY64320.1 - 6.5e-53 179.1 0.0 1.9e-52 177.6 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 KEY64320.1 - 6e-23 80.7 0.0 1.2e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 KEY64320.1 - 9.5e-21 73.5 5.9 8.1e-10 38.5 0.9 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 KEY64320.1 - 6.1e-15 54.5 0.0 0.00075 19.3 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEY64320.1 - 2.9e-06 26.8 4.0 0.48 10.1 0.0 3.5 3 0 0 3 3 3 3 TPR repeat TPR_8 PF13181.1 KEY64320.1 - 7.2e-05 22.2 1.3 0.32 10.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEY64320.1 - 0.0033 17.2 2.5 4 7.5 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEY64320.1 - 0.023 14.8 1.4 11 6.5 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat NPR3 PF03666.8 KEY64320.1 - 0.08 11.4 2.2 0.18 10.3 1.5 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DNA_pol_phi PF04931.8 KEY64320.1 - 0.39 8.4 15.1 0.76 7.4 10.5 1.4 1 0 0 1 1 1 0 DNA polymerase phi Vfa1 PF08432.5 KEY64320.1 - 2.3 8.1 12.1 0.12 12.4 3.6 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 AF-4 PF05110.8 KEY64320.1 - 5.2 4.8 22.8 0.067 11.0 10.4 1.6 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Ferric_reduct PF01794.14 KEY64322.1 - 1.7e-18 66.9 9.1 3.8e-18 65.7 6.3 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KEY64322.1 - 6.5e-18 65.1 0.0 3.4e-15 56.2 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KEY64322.1 - 1.3e-16 60.4 0.0 6.9e-16 58.0 0.0 2.1 1 1 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.1 KEY64322.1 - 0.094 12.8 12.2 0.099 12.7 1.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) Nuc_sug_transp PF04142.10 KEY64323.1 - 1.2e-09 37.6 1.0 1.6e-09 37.2 0.2 1.6 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 KEY64323.1 - 4.2e-08 33.2 23.8 5.8e-06 26.3 1.2 3.4 3 1 1 4 4 4 3 EamA-like transporter family UAA PF08449.6 KEY64323.1 - 1.3e-06 27.5 6.6 2.3e-06 26.7 4.6 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KEY64323.1 - 8.8e-06 25.4 14.7 0.0078 15.8 0.7 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family DUF2407_C PF13373.1 KEY64323.1 - 0.62 9.9 2.6 2.4 8.0 1.5 2.2 2 0 0 2 2 2 0 DUF2407 C-terminal domain Yippee-Mis18 PF03226.9 KEY64324.1 - 2.1e-22 78.9 0.4 2.4e-22 78.7 0.3 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Evr1_Alr PF04777.8 KEY64324.1 - 0.035 13.9 0.8 1.1 9.2 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family Elf1 PF05129.8 KEY64324.1 - 0.061 13.0 0.3 0.48 10.1 0.0 2.0 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DUF2039 PF10217.4 KEY64324.1 - 0.076 13.0 2.2 0.2 11.6 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DUF2985 PF11204.3 KEY64325.1 - 6.4e-39 131.5 1.7 1.2e-38 130.6 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Sen15 PF09631.5 KEY64326.1 - 1.1e-30 105.8 0.0 1.5e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 Sen15 protein ADH_N PF08240.7 KEY64327.1 - 2.6e-30 104.3 1.4 4.8e-30 103.5 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY64327.1 - 6.7e-18 64.4 0.0 1.7e-17 63.2 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY64327.1 - 0.0069 17.2 0.0 0.019 15.8 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KEY64327.1 - 0.017 14.7 0.0 0.037 13.6 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Nucleoplasmin PF03066.10 KEY64328.1 - 0.0041 16.6 0.1 0.0041 16.6 0.1 1.1 1 0 0 1 1 1 1 Nucleoplasmin Myc_N PF01056.13 KEY64328.1 - 0.058 12.5 0.1 0.058 12.5 0.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region RNase_H2_suC PF08615.6 KEY64328.1 - 1.5 8.6 3.5 31 4.3 0.0 2.0 1 1 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CENP-B_dimeris PF09026.5 KEY64328.1 - 1.6 8.9 7.3 2.2 8.5 5.1 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 KEY64328.1 - 1.9 8.8 7.7 2.5 8.4 5.3 1.3 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LysM PF01476.15 KEY64329.1 - 2.7e-16 59.1 0.2 4.4e-05 23.2 0.0 5.1 5 0 0 5 5 5 3 LysM domain Glyco_hydro_18 PF00704.23 KEY64330.1 - 2.4e-80 270.5 1.2 4.5e-80 269.6 0.6 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KEY64330.1 - 3.9e-09 36.3 10.7 3.9e-09 36.3 7.4 4.4 4 0 0 4 4 4 1 Chitin recognition protein DUF2457 PF10446.4 KEY64331.1 - 0.021 13.5 0.4 0.028 13.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) 2OG-FeII_Oxy_3 PF13640.1 KEY64332.1 - 3.5e-08 33.8 0.1 5.2e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KEY64332.1 - 0.0027 17.3 0.1 0.0082 15.7 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ABC_membrane PF00664.18 KEY64333.1 - 1.7e-82 276.9 32.9 2.9e-44 151.5 5.6 2.5 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KEY64333.1 - 3.3e-51 173.2 0.0 9.8e-31 106.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KEY64333.1 - 6.4e-10 38.6 3.1 0.0068 15.6 0.0 4.3 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEY64333.1 - 4.8e-05 23.4 0.1 3.3 7.6 0.0 4.1 4 0 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.18 KEY64333.1 - 0.0001 22.2 0.1 0.49 10.3 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KEY64333.1 - 0.00016 21.7 2.0 0.021 14.8 0.5 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KEY64333.1 - 0.00028 20.1 0.0 0.23 10.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KEY64333.1 - 0.00039 19.8 0.8 0.57 9.7 0.0 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KEY64333.1 - 0.00093 18.6 0.1 0.62 9.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KEY64333.1 - 0.00096 19.6 0.3 2.2 8.7 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein AAA_23 PF13476.1 KEY64333.1 - 0.002 18.4 0.2 0.56 10.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 KEY64333.1 - 0.0031 16.9 0.1 2.9 7.3 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family Dynamin_N PF00350.18 KEY64333.1 - 0.017 14.9 1.5 0.92 9.3 0.1 2.5 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.12 KEY64333.1 - 0.032 14.0 1.9 0.73 9.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_17 PF13207.1 KEY64333.1 - 0.037 14.8 0.0 1.5 9.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KEY64333.1 - 0.056 13.5 0.8 21 5.2 0.1 3.2 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEY64333.1 - 0.066 13.3 0.0 3.4 7.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 KEY64333.1 - 0.097 11.7 0.1 5.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.1 KEY64333.1 - 0.11 12.0 2.4 3.2 7.2 0.0 3.2 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 KEY64333.1 - 0.18 11.4 0.7 0.86 9.2 0.1 2.3 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.12 KEY64333.1 - 0.2 11.1 1.0 11 5.4 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF1749 PF08538.5 KEY64334.1 - 1.6e-83 280.1 0.0 8.2e-83 277.7 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KEY64334.1 - 1.1e-14 54.8 0.0 1.6e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY64334.1 - 3.2e-09 36.6 0.0 7.3e-09 35.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KEY64334.1 - 0.00076 18.9 0.1 0.51 9.7 0.1 2.9 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KEY64334.1 - 0.0053 15.9 0.0 0.29 10.3 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2305 PF10230.4 KEY64334.1 - 0.072 12.4 0.0 4.7 6.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 KEY64334.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein HEAT_2 PF13646.1 KEY64335.1 - 2.1e-05 24.7 7.5 2 8.7 0.0 6.8 7 0 0 7 7 7 2 HEAT repeats HEAT_EZ PF13513.1 KEY64335.1 - 0.045 14.2 8.4 7 7.2 0.0 6.5 7 0 0 7 7 7 0 HEAT-like repeat Xpo1 PF08389.7 KEY64335.1 - 0.13 12.1 8.4 1.9 8.3 0.0 5.0 6 0 0 6 6 6 0 Exportin 1-like protein HEAT PF02985.17 KEY64335.1 - 0.31 11.2 4.7 45 4.5 0.1 5.3 5 0 0 5 5 5 0 HEAT repeat NUDIX PF00293.23 KEY64336.1 - 7.7e-17 61.2 0.0 1.3e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 KEY64336.1 - 2e-09 37.6 0.0 1.1e-08 35.3 0.0 2.1 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 KEY64336.1 - 3.9e-07 29.4 0.6 7.3e-07 28.5 0.4 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain PQ-loop PF04193.9 KEY64337.1 - 3.6e-37 125.7 16.4 2.1e-19 68.7 0.5 2.8 3 0 0 3 3 3 2 PQ loop repeat DUF3784 PF12650.2 KEY64337.1 - 0.33 10.9 4.2 0.25 11.3 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3784) CoaE PF01121.15 KEY64338.1 - 1.1e-44 151.9 0.0 4.9e-44 149.8 0.0 1.8 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 KEY64338.1 - 0.00029 21.1 0.3 0.18 12.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KEY64338.1 - 0.00061 19.6 0.0 0.0082 16.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 KEY64338.1 - 0.0012 19.6 0.3 0.0042 17.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 KEY64338.1 - 0.036 13.9 0.0 8.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase Tim17 PF02466.14 KEY64339.1 - 8.6e-26 90.4 2.9 1.4e-25 89.7 2.0 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family 5TM-5TMR_LYT PF07694.7 KEY64339.1 - 0.14 11.4 5.3 1 8.6 3.9 1.9 1 1 1 2 2 2 0 5TMR of 5TMR-LYT Arylsulfotrans PF05935.6 KEY64340.1 - 0.14 10.5 0.0 0.21 10.0 0.0 1.2 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) LON PF02190.11 KEY64342.1 - 6e-24 84.8 0.0 1e-23 84.0 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_4 PF15227.1 KEY64342.1 - 9.4e-13 47.8 17.9 1e-06 28.4 5.2 2.8 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KEY64342.1 - 7e-12 45.1 25.0 5.7e-09 35.8 7.4 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEY64342.1 - 2.7e-10 39.9 25.9 2.6e-08 33.5 7.8 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.20 KEY64342.1 - 4.6e-10 38.9 20.0 1.3e-07 31.1 6.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY64342.1 - 8e-10 38.2 22.4 3.3e-07 29.9 6.4 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KEY64342.1 - 9e-10 38.0 19.2 1.1e-08 34.5 4.9 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KEY64342.1 - 2.8e-07 30.1 13.2 3.1e-06 26.8 0.8 3.3 2 1 1 3 3 3 2 RING-type zinc-finger U-box PF04564.10 KEY64342.1 - 9.3e-05 22.3 0.0 0.0082 16.0 0.0 2.9 3 0 0 3 3 3 1 U-box domain zf-RING_4 PF14570.1 KEY64342.1 - 0.0017 17.9 7.0 0.0017 17.9 4.9 2.7 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 KEY64342.1 - 0.0087 15.5 3.9 0.0087 15.5 2.7 2.2 2 1 0 2 2 1 1 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.9 KEY64342.1 - 0.011 15.1 6.6 0.011 15.1 4.6 2.3 3 0 0 3 3 2 0 P-11 zinc finger zf-RING_6 PF14835.1 KEY64342.1 - 0.026 14.2 13.3 0.51 10.1 1.7 2.6 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DZR PF12773.2 KEY64342.1 - 0.12 12.2 0.3 0.12 12.2 0.2 2.9 2 1 1 3 3 3 0 Double zinc ribbon Prok-RING_4 PF14447.1 KEY64342.1 - 0.94 9.0 14.1 5.6 6.5 5.0 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 KEY64342.1 - 1.1 9.4 15.2 0.058 13.5 5.9 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger Baculo_IE-1 PF05290.6 KEY64342.1 - 1.8 8.3 5.7 2 8.1 1.0 2.3 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) tRNA-synt_1b PF00579.20 KEY64343.1 - 2.3e-57 194.3 0.0 2.7e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Complex1_LYR PF05347.10 KEY64344.1 - 1.8e-10 40.4 2.1 2.5e-10 39.9 1.5 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KEY64344.1 - 1.2e-08 34.9 1.0 1.8e-08 34.4 0.7 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Histone PF00125.19 KEY64345.1 - 8.5e-26 89.8 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KEY64345.1 - 1.3e-05 25.1 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KEY64346.1 - 1.6e-22 79.3 0.2 2.3e-22 78.9 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KEY64346.1 - 2e-05 24.5 0.0 5.3e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KEY64346.1 - 0.00027 21.1 0.0 0.00046 20.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 KEY64346.1 - 0.013 14.9 0.1 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 KEY64346.1 - 0.044 14.3 0.5 0.059 13.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) R3H PF01424.17 KEY64347.1 - 6e-12 45.0 0.0 1.4e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 KEY64347.1 - 3.9e-10 39.3 0.5 8.8e-10 38.2 0.4 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KEY64347.1 - 0.00028 20.6 2.1 0.00042 20.1 0.2 2.3 2 0 0 2 2 2 1 DExH-box splicing factor binding site Peptidase_C54 PF03416.14 KEY64348.1 - 1.5e-89 299.8 0.0 2e-89 299.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 DnaJ PF00226.26 KEY64349.1 - 4.2e-25 87.2 5.5 7e-25 86.5 0.8 2.6 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 KEY64349.1 - 3.1e-11 43.0 8.1 5e-10 39.2 0.6 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEY64349.1 - 6.7e-11 41.9 8.0 5.9e-09 35.8 1.0 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KEY64349.1 - 5.8e-09 35.9 7.5 0.00029 20.9 0.3 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KEY64349.1 - 2e-06 27.8 7.6 0.014 15.6 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY64349.1 - 1.4e-05 25.0 6.8 0.021 15.1 1.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KEY64349.1 - 0.00011 21.9 6.0 0.012 15.4 0.9 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEY64349.1 - 0.0049 17.0 0.3 3.2 8.1 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger double domain RPT PF13446.1 KEY64349.1 - 0.0093 15.3 0.1 0.046 13.1 0.0 2.1 2 0 0 2 2 2 1 A repeated domain in UCH-protein CpXC PF14353.1 KEY64349.1 - 0.045 13.7 0.3 12 5.8 0.0 2.6 2 0 0 2 2 2 0 CpXC protein DUF2387 PF09526.5 KEY64349.1 - 0.11 12.4 4.3 0.18 11.7 0.5 2.6 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) UvrC_HhH_N PF08459.6 KEY64349.1 - 0.63 9.5 3.5 0.56 9.7 0.0 2.6 3 0 0 3 3 3 0 UvrC Helix-hairpin-helix N-terminal SPX PF03105.14 KEY64350.1 - 3.2e-37 128.8 0.0 4e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 KEY64350.1 - 3.2e-07 30.1 9.8 3.2e-07 30.1 6.8 1.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KEY64350.1 - 5.1e-07 29.2 10.2 1.2e-06 28.0 7.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEY64350.1 - 1.2e-06 28.2 11.9 1.6e-05 24.5 8.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KEY64350.1 - 8.2e-06 25.3 9.5 1.7e-05 24.3 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY64350.1 - 8.8e-06 25.3 7.7 2.5e-05 23.9 5.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEY64350.1 - 1.1e-05 25.3 12.6 4.1e-05 23.5 8.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEY64350.1 - 0.0093 16.0 3.7 0.03 14.4 2.6 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger TerY-C PF15616.1 KEY64350.1 - 0.014 15.3 2.8 0.016 15.1 1.0 1.8 2 0 0 2 2 2 0 TerY-C metal binding domain zf-RING_UBOX PF13445.1 KEY64350.1 - 0.031 13.9 7.7 0.093 12.4 5.3 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 KEY64350.1 - 0.44 10.1 10.1 0.11 12.1 3.9 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.2 KEY64350.1 - 1.2 9.0 4.4 4.5 7.1 3.3 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-Apc11 PF12861.2 KEY64350.1 - 1.4 8.8 5.4 4.2 7.2 3.8 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Cys_Met_Meta_PP PF01053.15 KEY64351.1 - 2e-31 108.6 0.0 2.7e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KEY64351.1 - 0.17 10.8 0.0 0.32 9.8 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class I and II EMG1 PF03587.9 KEY64353.1 - 7.9e-78 260.3 0.0 9.4e-78 260.1 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase 2-oxoacid_dh PF00198.18 KEY64354.1 - 6e-80 267.8 0.1 1.1e-79 266.9 0.1 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KEY64354.1 - 3.9e-18 64.8 2.5 7.8e-18 63.8 1.7 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KEY64354.1 - 0.00062 19.3 1.2 0.017 14.7 0.3 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like Tape_meas_lam_C PF09718.5 KEY64354.1 - 0.093 12.6 0.1 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Trypan_PARP PF05887.6 KEY64354.1 - 0.45 10.3 18.0 0.76 9.5 12.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3614 PF12267.3 KEY64354.1 - 0.48 10.6 6.9 1 9.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3614) Ndc1_Nup PF09531.5 KEY64354.1 - 1.8 6.8 7.9 2.4 6.4 5.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PRCC PF10253.4 KEY64354.1 - 2.8 8.6 16.1 0.96 10.1 9.1 1.6 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting RR_TM4-6 PF06459.7 KEY64354.1 - 4.2 7.1 12.3 5.8 6.7 8.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_S17 PF00366.15 KEY64355.1 - 6e-08 32.6 0.8 6e-08 32.6 0.6 2.1 2 1 0 2 2 2 1 Ribosomal protein S17 RR_TM4-6 PF06459.7 KEY64355.1 - 0.014 15.2 1.8 0.016 15.1 1.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GTP_EFTU_D2 PF03144.20 KEY64355.1 - 0.04 14.0 0.1 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 2 AAA PF00004.24 KEY64356.1 - 1.2e-38 132.3 0.0 2.4e-38 131.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KEY64356.1 - 5e-08 32.7 0.0 4.9e-06 26.3 0.0 3.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 KEY64356.1 - 3.3e-06 27.2 0.3 0.00016 21.8 0.1 3.1 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KEY64356.1 - 8.8e-05 21.6 0.0 0.00016 20.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 KEY64356.1 - 0.00054 18.7 0.0 0.00093 18.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 KEY64356.1 - 0.00055 19.9 0.1 0.0022 18.0 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 KEY64356.1 - 0.0012 18.8 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 KEY64356.1 - 0.0019 17.6 0.0 0.0038 16.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 KEY64356.1 - 0.0021 17.8 0.1 0.0069 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KEY64356.1 - 0.0029 16.7 0.1 0.0077 15.4 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 KEY64356.1 - 0.0036 16.9 1.5 0.012 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEY64356.1 - 0.0062 16.2 0.2 0.026 14.2 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 KEY64356.1 - 0.0065 16.3 0.0 0.021 14.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KEY64356.1 - 0.0088 14.9 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KEY64356.1 - 0.021 15.6 0.0 0.072 13.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 KEY64356.1 - 0.024 14.5 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KEY64356.1 - 0.025 14.1 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KEY64356.1 - 0.028 13.8 0.2 0.25 10.7 0.1 2.2 1 1 0 2 2 2 0 AAA domain PhoH PF02562.11 KEY64356.1 - 0.045 12.9 0.1 0.31 10.2 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.1 KEY64356.1 - 0.076 12.9 0.5 0.24 11.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KEY64356.1 - 0.078 12.6 0.0 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Guanylate_kin PF00625.16 KEY64356.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Guanylate kinase Arch_ATPase PF01637.13 KEY64356.1 - 0.091 12.4 0.0 0.43 10.2 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase Sigma54_activat PF00158.21 KEY64356.1 - 0.11 12.0 0.0 0.27 10.6 0.0 1.6 1 1 1 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 KEY64356.1 - 0.13 12.4 0.1 0.66 10.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase COG6 PF06419.6 KEY64357.1 - 1.3e-207 690.7 1.8 1.5e-207 690.5 1.3 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 RmuC PF02646.11 KEY64357.1 - 0.009 14.8 0.7 0.009 14.8 0.5 2.8 3 0 0 3 3 3 1 RmuC family COG2 PF06148.6 KEY64357.1 - 0.97 9.3 6.5 0.44 10.4 0.4 3.2 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 APG9 PF04109.11 KEY64358.1 - 1.4e-154 514.5 4.4 1.9e-154 514.0 3.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 Mito_carr PF00153.22 KEY64358.1 - 1.8e-71 235.9 6.4 4.9e-25 87.0 0.3 3.4 2 1 1 3 3 3 3 Mitochondrial carrier protein DnaJ PF00226.26 KEY64359.1 - 8.9e-25 86.2 7.6 2e-23 81.9 1.0 2.8 2 0 0 2 2 2 2 DnaJ domain TPR_11 PF13414.1 KEY64359.1 - 4e-19 68.0 14.9 8.4e-09 34.9 0.0 5.5 5 1 1 6 6 5 4 TPR repeat TPR_1 PF00515.23 KEY64359.1 - 1.5e-16 59.1 0.1 0.001 18.5 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEY64359.1 - 1.7e-15 57.2 14.0 0.00011 22.7 0.8 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEY64359.1 - 2e-13 49.1 13.6 0.014 15.3 0.0 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 KEY64359.1 - 5.6e-13 48.5 0.4 0.0034 17.1 0.0 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEY64359.1 - 5.6e-10 38.2 0.9 0.024 14.4 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEY64359.1 - 1.5e-09 37.5 15.7 0.042 14.4 0.0 7.8 5 2 3 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEY64359.1 - 2.2e-09 36.7 8.7 0.0014 18.6 0.1 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEY64359.1 - 1.5e-08 34.8 17.0 0.0079 16.5 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 KEY64359.1 - 9.3e-07 28.8 10.9 0.01 15.9 0.3 4.7 3 2 2 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KEY64359.1 - 2.5e-05 24.1 19.6 0.097 12.6 0.3 5.3 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEY64359.1 - 3.7e-05 23.1 5.3 1.3 8.9 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEY64359.1 - 6.4e-05 23.1 19.3 0.42 11.1 0.0 6.9 8 0 0 8 8 7 3 Tetratricopeptide repeat Fae PF08714.6 KEY64359.1 - 0.19 11.4 2.4 0.099 12.3 0.2 1.6 2 0 0 2 2 2 0 Formaldehyde-activating enzyme (Fae) CENP-F_leu_zip PF10473.4 KEY64360.1 - 0.018 14.9 5.7 0.46 10.3 3.5 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Dor1 PF04124.7 KEY64360.1 - 0.029 12.8 1.5 0.047 12.1 1.0 1.2 1 0 0 1 1 1 0 Dor1-like family Phlebovirus_NSM PF07246.6 KEY64360.1 - 0.037 13.1 0.3 0.053 12.6 0.2 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M BLOC1_2 PF10046.4 KEY64360.1 - 0.069 13.2 2.0 0.47 10.6 0.2 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TEX12 PF15219.1 KEY64360.1 - 0.082 12.8 1.1 0.27 11.2 0.1 2.2 2 1 1 3 3 3 0 Testis-expressed 12 GAS PF13851.1 KEY64360.1 - 0.22 10.7 3.2 3.5 6.7 0.1 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4404 PF14357.1 KEY64360.1 - 2.1 8.8 14.4 1.2 9.6 0.4 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4404) IncA PF04156.9 KEY64360.1 - 2.6 7.5 11.6 0.43 10.1 4.1 2.2 1 1 1 2 2 2 0 IncA protein PspB PF06667.7 KEY64360.1 - 9.4 6.2 12.9 2.9 7.8 0.2 4.2 4 2 2 6 6 6 0 Phage shock protein B Vac14_Fig4_bd PF11916.3 KEY64361.1 - 1.7e-81 271.6 5.1 1.7e-81 271.6 3.5 1.9 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 KEY64361.1 - 8.8e-46 154.2 0.0 3.8e-42 142.5 0.0 4.2 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 KEY64361.1 - 1e-10 40.7 1.6 0.00013 21.7 0.0 5.7 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 KEY64361.1 - 6.9e-09 35.9 3.0 0.00031 21.1 0.1 5.5 4 0 0 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.1 KEY64361.1 - 2.4e-07 30.9 0.7 0.0059 16.8 0.0 4.5 4 0 0 4 4 4 2 HEAT repeats Cnd1 PF12717.2 KEY64361.1 - 0.00019 21.3 0.4 3.8 7.3 0.0 3.8 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 KEY64361.1 - 0.0034 17.1 0.0 0.39 10.6 0.0 3.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Ipi1_N PF12333.3 KEY64361.1 - 0.0069 16.3 0.0 0.06 13.3 0.0 2.5 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation FA_desaturase PF00487.19 KEY64362.1 - 5.6e-39 134.1 21.6 8.3e-39 133.5 15.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KEY64362.1 - 1.1e-13 50.7 0.0 2.4e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pyr_redox_dim PF02852.17 KEY64363.1 - 1.5e-38 131.1 0.2 8.5e-38 128.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KEY64363.1 - 3.1e-37 128.4 7.1 8.8e-37 126.9 4.9 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY64363.1 - 9.2e-25 86.8 10.5 7.5e-21 74.3 0.6 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY64363.1 - 4.5e-11 42.6 2.8 2.9e-06 27.1 0.3 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KEY64363.1 - 4.8e-10 39.0 8.8 8.9e-10 38.2 0.2 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 KEY64363.1 - 1.3e-09 37.4 8.0 9e-08 31.3 2.4 2.5 2 1 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KEY64363.1 - 1.1e-08 35.4 1.0 3.4e-05 24.0 0.2 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEY64363.1 - 1.9e-08 33.5 11.0 3.8e-07 29.3 2.1 3.3 3 1 0 3 3 3 2 FAD binding domain DAO PF01266.19 KEY64363.1 - 2.8e-07 29.7 18.8 0.00012 21.0 1.6 4.1 3 1 0 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.9 KEY64363.1 - 3.2e-06 25.9 13.0 5.8e-05 21.7 1.2 4.1 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.12 KEY64363.1 - 4e-06 26.1 4.7 4.9e-05 22.5 0.1 2.5 2 1 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 KEY64363.1 - 0.00012 21.1 0.3 0.62 8.9 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 KEY64363.1 - 0.00026 20.5 3.3 0.37 10.3 0.4 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 KEY64363.1 - 0.00073 18.6 10.4 0.097 11.7 0.9 2.8 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KEY64363.1 - 0.0017 17.3 3.1 0.007 15.3 0.1 2.5 3 1 0 3 3 3 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 KEY64363.1 - 0.016 15.4 5.1 1.5 9.0 0.2 3.0 2 2 0 2 2 2 0 Putative NAD(P)-binding FMO-like PF00743.14 KEY64363.1 - 0.063 11.4 0.1 0.11 10.6 0.1 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like 3HCDH_N PF02737.13 KEY64363.1 - 0.23 11.0 7.7 0.14 11.8 0.4 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 KEY64363.1 - 0.39 9.2 6.9 0.052 12.1 0.4 2.1 2 0 0 2 2 2 0 Tryptophan halogenase MIF4G PF02854.14 KEY64364.1 - 1.3e-20 73.7 0.1 8.3e-20 71.0 0.1 2.1 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 KEY64364.1 - 5.7e-11 42.1 0.1 3.7e-08 33.0 0.0 2.9 2 1 0 2 2 2 2 MA3 domain SRP14 PF02290.10 KEY64365.1 - 1.9e-17 62.9 0.0 3e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle 14kD protein RRM_1 PF00076.17 KEY64366.1 - 6.6e-53 176.2 0.0 7.7e-18 63.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY64366.1 - 1.2e-41 140.5 0.0 1.1e-14 54.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY64366.1 - 1e-25 89.3 0.0 1.9e-07 30.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KEY64366.1 - 3.2e-07 30.0 0.0 0.39 10.5 0.0 4.1 3 2 0 3 3 3 3 Limkain b1 RRM_3 PF08777.6 KEY64366.1 - 3.1e-06 26.9 0.0 0.58 10.0 0.0 3.4 3 0 0 3 3 3 2 RNA binding motif ATP-grasp_2 PF08442.5 KEY64366.1 - 0.0006 19.2 0.0 0.077 12.3 0.0 2.9 3 0 0 3 3 3 1 ATP-grasp domain THRAP3_BCLAF1 PF15440.1 KEY64366.1 - 2.6 6.6 21.9 3.9 6.0 15.2 1.3 1 0 0 1 1 1 0 THRAP3/BCLAF1 family COQ9 PF08511.6 KEY64367.1 - 6.5e-30 102.4 0.0 1e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 COQ9 SMC_N PF02463.14 KEY64368.1 - 2.8e-19 69.2 10.5 1.4e-18 66.9 7.3 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KEY64368.1 - 5.4e-07 30.1 37.4 5.4e-07 30.1 25.9 5.6 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KEY64368.1 - 3.8e-05 23.8 2.8 0.00069 19.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KEY64368.1 - 0.0022 17.8 0.0 0.0083 16.0 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_hinge PF06470.8 KEY64368.1 - 0.0047 16.8 0.0 0.044 13.7 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.1 KEY64368.1 - 0.0049 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 KEY64368.1 - 0.0054 15.9 7.3 0.49 9.5 0.1 2.8 3 1 0 3 3 3 2 Reovirus sigma C capsid protein SGT1 PF07093.6 KEY64369.1 - 3.4e-144 481.4 32.8 5e-143 477.5 22.7 1.9 1 1 0 1 1 1 1 SGT1 protein THUMP PF02926.12 KEY64370.1 - 2.4e-09 37.2 0.9 1.4e-06 28.2 0.1 2.5 2 1 0 2 2 2 2 THUMP domain TPP_enzyme_N PF02776.13 KEY64371.1 - 2.9e-34 118.0 0.1 4.5e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KEY64371.1 - 6e-21 74.6 0.0 1.4e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KEY64371.1 - 1.7e-15 56.8 0.6 6e-15 55.1 0.0 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Evr1_Alr PF04777.8 KEY64372.1 - 1.5e-29 101.7 0.2 5e-29 100.0 0.0 1.8 2 0 0 2 2 2 1 Erv1 / Alr family HEM4 PF02602.10 KEY64373.1 - 6.6e-33 113.8 0.0 7.7e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TLD PF07534.11 KEY64374.1 - 2.6e-27 95.5 0.1 2.8e-14 53.3 0.1 2.2 2 0 0 2 2 2 2 TLD Pkinase PF00069.20 KEY64375.1 - 2.5e-74 249.6 0.0 3.5e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY64375.1 - 9.1e-32 110.1 0.0 1.2e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY64375.1 - 0.0007 18.6 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEY64375.1 - 0.0028 16.7 0.1 0.005 15.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEY64375.1 - 0.0084 15.8 0.1 0.014 15.0 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEY64375.1 - 0.071 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Gag_p6 PF08705.6 KEY64375.1 - 0.082 12.9 0.1 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Gag protein p6 S_100 PF01023.14 KEY64375.1 - 0.11 11.8 0.3 0.36 10.1 0.2 1.9 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Sec23_trunk PF04811.10 KEY64376.1 - 6.3e-69 232.0 0.0 1e-68 231.3 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KEY64376.1 - 8e-25 86.2 0.0 1.1e-23 82.6 0.0 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 KEY64376.1 - 9.2e-18 63.5 5.3 1.5e-17 62.8 3.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 KEY64376.1 - 1.7e-16 60.5 0.0 3.2e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 KEY64376.1 - 1.1e-09 37.8 0.1 5.6e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 Gelsolin repeat DUF1035 PF06281.7 KEY64377.1 - 0.0067 16.1 0.3 0.013 15.3 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1035) YajC PF02699.10 KEY64377.1 - 0.64 9.7 3.2 1.1 9.0 2.2 1.4 1 1 0 1 1 1 0 Preprotein translocase subunit Fungal_trans_2 PF11951.3 KEY64378.1 - 3.9e-07 28.9 0.1 7.4e-07 28.1 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Beta_protein PF14350.1 KEY64378.1 - 0.0076 15.4 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 Beta protein Xpo1 PF08389.7 KEY64379.1 - 2.1e-06 27.7 3.2 1.3e-05 25.1 0.0 3.8 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 KEY64379.1 - 0.0019 18.1 0.1 0.0019 18.1 0.1 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain IFRD PF05004.8 KEY64379.1 - 0.032 13.3 0.1 0.072 12.1 0.0 1.5 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) WD40 PF00400.27 KEY64380.1 - 0.00026 20.7 6.2 9.3 6.3 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF1917 PF08939.5 KEY64381.1 - 2.5e-56 191.1 1.2 6.3e-56 189.8 0.8 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) Mhr1 PF12829.2 KEY64381.1 - 0.067 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination Acetyltransf_1 PF00583.19 KEY64382.1 - 5.4e-17 61.5 0.0 8.3e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEY64382.1 - 2.6e-09 37.0 0.0 3.9e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEY64382.1 - 3.9e-09 36.1 0.0 6.3e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KEY64382.1 - 4.8e-09 36.3 0.0 7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KEY64382.1 - 5.9e-08 32.9 0.0 7.8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KEY64382.1 - 1.2e-06 28.5 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEY64382.1 - 3.9e-06 26.7 0.0 6.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KEY64382.1 - 0.007 16.3 0.0 0.0091 15.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KEY64382.1 - 0.041 13.7 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase LCAT PF02450.10 KEY64383.1 - 5.6e-94 315.2 0.0 7.2e-94 314.9 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF1778 PF08681.6 KEY64383.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1778) DUF2013 PF09431.5 KEY64384.1 - 3.7e-49 166.0 2.7 3.7e-49 166.0 1.8 1.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2013) PH PF00169.24 KEY64385.1 - 3.4e-11 43.2 0.0 7.2e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 KEY64385.1 - 0.016 12.7 0.3 0.025 12.1 0.2 1.2 1 0 0 1 1 1 0 Prominin Gar1 PF04410.9 KEY64386.1 - 1.7e-42 144.4 0.1 1.7e-42 144.4 0.1 1.9 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region CDP-OH_P_transf PF01066.16 KEY64387.1 - 1.9e-13 50.5 4.0 3.4e-13 49.7 2.7 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Metallopep PF12044.3 KEY64388.1 - 1e-158 528.2 0.0 1.4e-158 527.8 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 KEY64388.1 - 0.00035 20.4 0.0 0.00069 19.5 0.0 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_2 PF13574.1 KEY64388.1 - 0.028 14.4 0.3 0.059 13.4 0.2 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KEY64388.1 - 0.54 10.1 6.9 0.054 13.4 1.1 1.9 2 1 0 2 2 2 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KEY64388.1 - 1.9 7.9 4.7 0.29 10.6 0.2 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Whi5 PF08528.6 KEY64389.1 - 1.3e-07 31.0 0.1 4.7e-07 29.2 0.1 1.9 2 0 0 2 2 2 1 Whi5 like Syndecan PF01034.15 KEY64390.1 - 0.0036 16.9 1.2 0.0065 16.0 0.8 1.3 1 0 0 1 1 1 1 Syndecan domain Herpes_gE PF02480.11 KEY64390.1 - 0.011 14.0 0.0 0.011 14.0 0.0 2.3 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Shisa PF13908.1 KEY64390.1 - 1.8 8.6 0.0 1.8 8.6 0.0 3.5 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator PNP_UDP_1 PF01048.15 KEY64393.1 - 0.04 12.9 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Phosphorylase superfamily SurE PF01975.12 KEY64394.1 - 6e-20 71.3 0.0 8.3e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE H_lectin PF09458.5 KEY64395.1 - 9.4e-15 54.0 0.2 2.2e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 H-type lectin domain Matrilin_ccoil PF10393.4 KEY64395.1 - 0.0096 15.2 0.1 0.053 12.8 0.0 2.3 2 0 0 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin FAD_binding_4 PF01565.18 KEY64400.1 - 1.2e-16 60.3 0.2 2.3e-16 59.5 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY64400.1 - 3.7e-07 29.9 0.2 8.2e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Fungal_trans PF04082.13 KEY64401.1 - 2.6e-26 92.0 0.1 4e-26 91.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.8 KEY64401.1 - 0.0057 16.5 0.3 0.013 15.4 0.2 1.6 1 0 0 1 1 1 1 Gal4-like dimerisation domain Zn_clus PF00172.13 KEY64401.1 - 0.055 13.3 5.6 0.097 12.6 3.8 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KEY64402.1 - 2e-89 300.2 22.1 2.4e-89 299.9 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY64402.1 - 7e-30 103.9 33.7 8.8e-28 97.0 14.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEY64402.1 - 0.00023 19.7 26.9 0.00025 19.5 1.0 3.4 2 1 1 3 3 3 2 MFS/sugar transport protein DUF2063 PF09836.4 KEY64402.1 - 0.064 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2063) DUF2754 PF10953.3 KEY64402.1 - 6.4 6.9 8.4 0.51 10.4 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) adh_short PF00106.20 KEY64403.1 - 7.9e-26 90.9 0.5 9.6e-26 90.6 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY64403.1 - 2.8e-20 73.1 0.0 4.7e-20 72.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY64403.1 - 1.1e-13 51.2 0.3 1.8e-13 50.5 0.2 1.4 1 1 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 KEY64403.1 - 0.0068 15.5 0.1 0.02 14.0 0.0 1.6 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KEY64403.1 - 0.042 12.7 0.0 0.057 12.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pneumo_ncap PF03246.8 KEY64403.1 - 0.13 10.7 0.1 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Pneumovirus nucleocapsid protein Zeta_toxin PF06414.7 KEY64404.1 - 1.5e-07 30.7 0.3 1.4e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 KEY64404.1 - 4.2e-07 29.6 1.4 1.1e-06 28.3 0.8 2.0 1 1 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KEY64404.1 - 2.6e-06 28.2 0.1 6.4e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEY64404.1 - 3.8e-06 27.0 0.0 6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 KEY64404.1 - 2.8e-05 24.4 0.1 0.00013 22.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KEY64404.1 - 7.7e-05 22.5 0.1 0.00025 20.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KEY64404.1 - 0.00037 20.6 0.0 0.00064 19.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 KEY64404.1 - 0.00079 19.1 0.2 0.0063 16.2 0.0 2.1 2 0 0 2 2 2 1 NTPase AAA_22 PF13401.1 KEY64404.1 - 0.001 19.2 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KEY64404.1 - 0.0015 17.7 0.0 0.0024 17.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 T2SE PF00437.15 KEY64404.1 - 0.0022 16.9 0.0 0.0037 16.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 KEY64404.1 - 0.0039 16.8 0.0 0.0053 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KEY64404.1 - 0.0058 16.5 0.7 0.032 14.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KEY64404.1 - 0.006 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 KEY64404.1 - 0.0068 16.0 0.0 0.041 13.5 0.0 2.0 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.16 KEY64404.1 - 0.0084 15.2 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI cobW PF02492.14 KEY64404.1 - 0.01 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain PRK PF00485.13 KEY64404.1 - 0.013 15.0 0.0 0.019 14.5 0.0 1.3 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RuvB_N PF05496.7 KEY64404.1 - 0.014 14.4 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NB-ARC PF00931.17 KEY64404.1 - 0.016 14.0 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain SRP54 PF00448.17 KEY64404.1 - 0.033 13.6 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 KEY64404.1 - 0.051 13.0 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 KEY64404.1 - 0.057 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase CPT PF07931.7 KEY64404.1 - 0.063 12.9 1.2 0.38 10.3 0.8 2.0 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_25 PF13481.1 KEY64404.1 - 0.07 12.5 0.1 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.10 KEY64404.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_14 PF13173.1 KEY64404.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.13 KEY64404.1 - 0.11 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase APS_kinase PF01583.15 KEY64404.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase ATP_bind_1 PF03029.12 KEY64404.1 - 0.15 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_11 PF13086.1 KEY64404.1 - 0.16 11.5 0.0 0.17 11.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain ADH_N PF08240.7 KEY64405.1 - 1.1e-31 108.8 0.3 1.1e-31 108.8 0.2 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY64405.1 - 6.2e-23 80.7 1.2 9.9e-23 80.1 0.8 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY64405.1 - 0.00016 22.5 0.0 0.00043 21.1 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KEY64405.1 - 0.0002 21.8 0.3 0.0005 20.6 0.2 1.7 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.14 KEY64405.1 - 0.0032 16.6 0.1 0.0054 15.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 KEY64405.1 - 0.014 15.8 0.0 0.033 14.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 KEY64405.1 - 0.015 14.3 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 KEY64405.1 - 0.017 14.7 0.1 0.031 13.8 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KEY64405.1 - 0.03 14.0 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AdoHcyase_NAD PF00670.16 KEY64405.1 - 0.22 11.3 3.2 14 5.5 0.0 2.3 1 1 1 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain adh_short PF00106.20 KEY64406.1 - 3.3e-36 124.7 5.4 3.3e-36 124.7 3.7 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY64406.1 - 7.5e-24 84.8 0.8 9.2e-24 84.5 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY64406.1 - 8.2e-17 61.4 3.1 1.1e-16 61.0 2.2 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 KEY64406.1 - 0.00078 18.5 0.5 0.078 12.0 0.0 2.3 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 KEY64406.1 - 0.0025 17.3 1.3 0.0065 15.9 0.9 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY64406.1 - 0.0046 16.9 2.9 0.011 15.7 2.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KEY64406.1 - 0.014 14.3 1.2 1.6 7.5 0.0 2.3 1 1 1 2 2 2 0 RmlD substrate binding domain Tom22 PF04281.8 KEY64406.1 - 0.055 13.0 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 adh_short PF00106.20 KEY64407.1 - 7.1e-17 61.8 0.5 1.1e-16 61.1 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY64407.1 - 2.5e-08 33.8 0.2 5.3e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY64407.1 - 0.0029 17.4 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FAD_binding_3 PF01494.14 KEY64408.1 - 6.7e-44 150.3 0.0 9.6e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Abhydrolase_5 PF12695.2 KEY64410.1 - 4.1e-14 52.5 0.0 8.4e-14 51.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY64410.1 - 5.3e-13 49.3 0.1 7.4e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KEY64410.1 - 1.6e-05 24.2 0.1 0.00028 20.2 0.1 2.5 2 1 0 2 2 2 1 Dienelactone hydrolase family DUF1100 PF06500.6 KEY64410.1 - 0.0012 17.4 0.0 0.0017 17.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) AXE1 PF05448.7 KEY64410.1 - 0.055 11.9 0.3 0.48 8.8 0.2 2.0 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 KEY64410.1 - 0.075 12.7 0.0 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal adh_short PF00106.20 KEY64411.1 - 8.7e-19 68.0 0.0 1.3e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY64411.1 - 8.9e-07 28.7 0.0 8.8e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KEY64411.1 - 0.0054 16.1 0.0 0.017 14.5 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Big_3 PF07523.7 KEY64413.1 - 7.4e-07 29.1 0.7 2.4e-06 27.5 0.5 1.9 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 3) Glyco_hydro_43 PF04616.9 KEY64413.1 - 2.4e-05 23.5 4.6 4.3e-05 22.7 3.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Big_2 PF02368.13 KEY64413.1 - 0.018 14.9 0.3 0.08 12.8 0.2 2.1 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 2) Amidase PF01425.16 KEY64414.1 - 7.2e-58 196.4 0.5 1.5e-54 185.5 0.2 2.1 2 0 0 2 2 2 2 Amidase Glyco_hydro_43 PF04616.9 KEY64414.1 - 9.4e-45 152.8 5.5 1.5e-44 152.1 3.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_1 PF00734.13 KEY64414.1 - 7.3e-11 41.5 14.3 7.3e-11 41.5 9.9 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain PMEI PF04043.10 KEY64415.1 - 0.0086 15.9 3.9 0.024 14.5 2.7 1.7 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor DUF883 PF05957.8 KEY64415.1 - 0.02 15.3 5.8 0.02 15.3 4.0 4.0 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF883) Tape_meas_lam_C PF09718.5 KEY64415.1 - 0.18 11.7 7.4 0.51 10.2 0.9 3.2 2 1 1 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) YtxH PF12732.2 KEY64415.1 - 0.74 10.2 11.4 45 4.4 0.4 4.2 3 1 1 4 4 4 0 YtxH-like protein PP_M1 PF03012.9 KEY64416.1 - 0.081 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoprotein Amidase PF01425.16 KEY64417.1 - 6.5e-18 64.8 3.5 9e-16 57.7 2.4 2.1 2 0 0 2 2 2 2 Amidase Sugar_tr PF00083.19 KEY64419.1 - 1.4e-82 277.7 20.4 1.6e-82 277.5 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY64419.1 - 1.6e-22 79.7 33.8 7.6e-20 70.9 18.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEY64419.1 - 6.7e-07 28.0 19.8 0.00053 18.5 4.2 3.1 2 2 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 KEY64419.1 - 0.0021 16.3 1.3 0.0037 15.5 0.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) zf-C2H2 PF00096.21 KEY64420.1 - 4.3e-13 48.7 33.7 1.8e-05 24.7 1.4 5.0 5 1 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY64420.1 - 3.5e-10 39.4 20.4 0.0013 18.8 0.7 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEY64420.1 - 7.9e-08 32.2 24.7 0.00032 20.8 2.8 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KEY64420.1 - 0.0026 17.8 17.4 0.05 13.7 1.1 4.4 2 1 1 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 KEY64420.1 - 0.011 15.3 3.2 0.014 15.0 0.8 2.2 1 1 1 2 2 2 0 zinc-finger of a C2HC-type zf-TRAF PF02176.13 KEY64420.1 - 0.17 12.2 12.1 0.49 10.7 5.4 3.0 1 1 2 3 3 3 0 TRAF-type zinc finger Ustilago_mating PF05722.7 KEY64420.1 - 0.19 11.0 3.4 5.7 6.1 0.9 2.3 2 0 0 2 2 2 0 Ustilago B locus mating-type protein zf-BED PF02892.10 KEY64420.1 - 0.47 10.2 13.0 1.5 8.6 5.0 3.1 2 1 1 3 3 3 0 BED zinc finger zf-H2C2_5 PF13909.1 KEY64420.1 - 0.51 10.6 13.3 2.1 8.7 0.6 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-met PF12874.2 KEY64420.1 - 2.7 8.2 8.2 76 3.7 0.1 4.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DDHD PF02862.12 KEY64421.1 - 2.1e-36 125.8 0.1 1.8e-19 70.4 0.0 3.0 3 0 0 3 3 3 2 DDHD domain Abhydrolase_6 PF12697.2 KEY64421.1 - 0.0033 17.3 0.0 0.0094 15.8 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY64421.1 - 0.012 15.3 0.0 0.033 13.9 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2305 PF10230.4 KEY64421.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF1227 PF06777.6 KEY64422.1 - 8.7e-63 210.3 1.6 1.3e-62 209.8 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 KEY64422.1 - 1.1e-50 171.3 0.9 2.6e-50 170.2 0.6 1.6 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 KEY64422.1 - 1.4e-43 148.6 0.0 4.2e-43 147.1 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 KEY64422.1 - 5e-06 25.5 0.0 2e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 KEY64422.1 - 0.0012 18.4 0.0 0.38 10.2 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 KEY64422.1 - 0.0096 15.7 0.7 0.065 13.0 0.2 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HrcA PF01628.16 KEY64422.1 - 0.011 15.2 2.0 0.25 10.8 0.1 2.4 2 0 0 2 2 2 0 HrcA protein C terminal domain AAA_22 PF13401.1 KEY64422.1 - 0.014 15.5 0.2 2.1 8.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 KEY64422.1 - 0.017 14.3 0.1 0.92 8.7 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.1 KEY64422.1 - 0.028 13.9 2.1 0.036 13.6 0.2 2.0 2 1 0 2 2 2 0 AAA domain OmpH PF03938.9 KEY64422.1 - 0.04 13.8 3.6 0.29 11.0 0.0 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) AAA_19 PF13245.1 KEY64422.1 - 0.12 12.1 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain DSPc PF00782.15 KEY64423.1 - 3.9e-22 78.2 0.0 1e-13 51.0 0.1 3.2 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEY64423.1 - 0.0011 18.3 0.1 0.0048 16.2 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase WD40 PF00400.27 KEY64424.1 - 9.4e-06 25.3 2.5 0.012 15.5 0.0 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Cupin_8 PF13621.1 KEY64425.1 - 3.2e-37 128.3 0.0 4.4e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 KEY64425.1 - 2.1e-22 79.5 0.0 3.1e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 KEY64425.1 - 0.0001 22.0 0.5 0.00081 19.1 0.0 2.7 2 0 0 2 2 2 1 Galactose oxidase, central domain Cupin_4 PF08007.7 KEY64425.1 - 0.0026 17.0 0.0 0.0043 16.3 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein MHYT PF03707.11 KEY64426.1 - 1.3e-07 31.5 27.3 2.5e-05 24.2 0.9 5.0 5 1 0 5 5 5 2 Bacterial signalling protein N terminal repeat DAO PF01266.19 KEY64427.1 - 6.3e-49 166.7 0.0 9.4e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KEY64427.1 - 1.4e-07 30.9 0.0 1.9e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEY64427.1 - 1.4e-06 27.4 1.4 1.2e-05 24.3 1.0 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KEY64427.1 - 0.00022 21.1 0.1 0.00072 19.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY64427.1 - 0.0038 17.2 0.1 0.01 15.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KEY64427.1 - 0.012 14.7 1.3 0.061 12.3 0.2 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 KEY64427.1 - 0.018 15.4 0.3 0.051 13.9 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEY64427.1 - 0.021 13.9 0.1 0.048 12.7 0.1 1.5 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 KEY64427.1 - 0.025 14.2 0.4 0.052 13.1 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 KEY64427.1 - 0.029 13.2 0.1 0.13 11.0 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KEY64427.1 - 0.044 12.6 0.0 0.16 10.8 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KEY64427.1 - 0.071 13.1 0.0 0.2 11.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEY64427.1 - 0.078 11.4 0.4 0.12 10.8 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein RGS PF00615.14 KEY64428.1 - 9.4e-12 45.0 0.0 1.3e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_C48 PF02902.14 KEY64429.1 - 1.6e-20 73.7 0.0 4.2e-20 72.2 0.0 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain FAD_binding_3 PF01494.14 KEY64430.1 - 4.1e-71 239.9 0.0 5.3e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KEY64430.1 - 5.6e-42 143.2 0.0 9.2e-42 142.5 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Lycopene_cycl PF05834.7 KEY64430.1 - 0.0022 17.0 0.0 0.0047 15.9 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 KEY64430.1 - 0.0034 17.7 0.0 0.0094 16.3 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY64430.1 - 0.0099 15.8 0.0 0.025 14.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KEY64430.1 - 0.013 14.5 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 KEY64430.1 - 0.02 14.7 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.1 KEY64430.1 - 0.035 14.3 0.0 0.077 13.3 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain ApbA PF02558.11 KEY64430.1 - 0.071 12.5 0.0 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 KEY64430.1 - 0.08 12.3 0.2 0.28 10.5 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 KEY64430.1 - 0.09 11.6 0.0 0.28 10.0 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase ThiF PF00899.16 KEY64430.1 - 0.16 11.7 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.13 KEY64430.1 - 0.19 11.7 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Rick_17kDa_Anti PF05433.10 KEY64432.1 - 2.3 7.9 15.5 11 5.7 9.7 2.1 1 1 1 2 2 2 0 Glycine zipper 2TM domain WD40 PF00400.27 KEY64433.1 - 2.3e-41 138.2 22.1 3.8e-11 42.4 0.2 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat MFS_1 PF07690.11 KEY64433.1 - 1.4e-21 76.6 57.7 3.2e-13 49.1 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Transket_pyr PF02779.19 KEY64434.1 - 6.7e-62 208.1 0.0 1.1e-61 207.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KEY64434.1 - 1.4e-55 188.1 0.0 2e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TFIIH_BTF_p62_N PF08567.6 KEY64435.1 - 4.5e-24 83.9 0.0 1.2e-23 82.4 0.0 1.7 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.12 KEY64435.1 - 1.3e-23 82.5 0.5 1.5e-13 50.2 0.0 2.7 2 0 0 2 2 2 2 BSD domain AAA PF00004.24 KEY64436.1 - 4.1e-38 130.5 0.0 8e-38 129.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEY64436.1 - 1.4e-06 28.4 0.1 0.002 18.1 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KEY64436.1 - 1.1e-05 25.6 0.1 0.0084 16.2 0.1 2.8 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 KEY64436.1 - 1.6e-05 24.1 0.0 3.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KEY64436.1 - 0.00022 22.0 0.1 0.00079 20.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEY64436.1 - 0.00046 20.0 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KEY64436.1 - 0.0018 18.1 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEY64436.1 - 0.0025 17.5 0.1 0.0075 15.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KEY64436.1 - 0.0072 15.5 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KEY64436.1 - 0.0089 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KEY64436.1 - 0.0094 15.6 0.1 0.024 14.4 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 KEY64436.1 - 0.016 13.9 0.0 0.031 13.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_25 PF13481.1 KEY64436.1 - 0.028 13.8 0.5 0.17 11.2 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 KEY64436.1 - 0.029 14.6 0.0 0.077 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEY64436.1 - 0.041 14.0 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 KEY64436.1 - 0.06 12.9 0.4 0.12 11.9 0.3 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KEY64436.1 - 0.061 12.4 0.0 0.16 11.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 KEY64436.1 - 0.078 12.6 0.3 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 KEY64436.1 - 0.09 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KEY64436.1 - 0.14 11.0 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) UPF0079 PF02367.12 KEY64436.1 - 0.22 11.1 0.1 7.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 KEY64436.1 - 0.39 9.5 0.0 0.65 8.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zn_clus PF00172.13 KEY64437.1 - 3.7e-07 29.9 12.3 6.2e-07 29.2 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEY64437.1 - 7.3e-05 21.5 0.0 0.00014 20.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain BLOC1_2 PF10046.4 KEY64438.1 - 0.15 12.2 4.3 1.5 8.9 0.9 2.9 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF883 PF05957.8 KEY64438.1 - 0.39 11.1 5.6 2 8.8 1.2 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Nsp1_C PF05064.8 KEY64438.1 - 0.54 9.9 4.0 11 5.7 0.8 2.6 2 0 0 2 2 2 0 Nsp1-like C-terminal region Nup54 PF13874.1 KEY64438.1 - 6.3 6.4 10.0 2.3 7.8 4.7 1.8 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF4140 PF13600.1 KEY64438.1 - 7.2 7.1 6.7 7.7 7.0 1.7 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) ATP-synt_ab PF00006.20 KEY64439.1 - 2.6e-61 206.8 0.0 3.8e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KEY64439.1 - 8.9e-25 87.3 0.4 1.7e-24 86.4 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KEY64439.1 - 1e-23 83.2 0.8 3.5e-23 81.5 0.4 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Arch_ATPase PF01637.13 KEY64439.1 - 0.003 17.2 0.0 0.0073 16.0 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 KEY64439.1 - 0.01 15.5 0.1 1 9.0 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KEY64439.1 - 0.011 15.4 0.0 0.031 13.9 0.0 1.8 1 1 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 KEY64439.1 - 0.014 14.8 0.3 0.046 13.1 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 KEY64439.1 - 0.016 14.4 0.1 0.03 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 KaiC PF06745.8 KEY64439.1 - 0.022 13.8 0.2 0.036 13.1 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 KEY64439.1 - 0.038 14.1 0.0 0.11 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KEY64439.1 - 0.066 13.1 0.5 0.3 11.0 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 KEY64439.1 - 0.076 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 KEY64439.1 - 0.11 11.3 0.5 0.61 8.8 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain Alpha-amylase_C PF02806.13 KEY64440.1 - 6.8e-26 90.2 0.1 1.8e-25 88.8 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 KEY64440.1 - 2.2e-18 66.7 0.8 1.6e-15 57.3 0.5 2.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CBM_48 PF02922.13 KEY64440.1 - 9.2e-17 60.8 0.1 2.5e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Cellulase PF00150.13 KEY64440.1 - 0.022 13.9 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) AAA_2 PF07724.9 KEY64441.1 - 1.1e-32 113.3 0.0 5.4e-32 111.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KEY64441.1 - 3.1e-12 46.8 0.0 6e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KEY64441.1 - 3.6e-08 33.2 0.0 7.7e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 KEY64441.1 - 2.4e-07 30.5 0.1 9.4e-07 28.6 0.0 2.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KEY64441.1 - 0.00018 22.3 0.8 0.00036 21.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KEY64441.1 - 0.00021 21.3 0.1 0.018 14.9 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEY64441.1 - 0.00049 20.2 0.5 0.0024 17.9 0.1 2.3 2 1 0 2 2 2 1 AAA domain MCM PF00493.18 KEY64441.1 - 0.00059 18.7 0.7 0.0011 17.8 0.0 1.7 2 0 0 2 2 2 1 MCM2/3/5 family AAA_14 PF13173.1 KEY64441.1 - 0.00062 19.6 0.1 0.0014 18.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 KEY64441.1 - 0.0016 17.9 0.0 0.0033 16.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein ResIII PF04851.10 KEY64441.1 - 0.052 13.3 0.6 0.2 11.4 0.0 2.2 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 KEY64441.1 - 0.057 12.5 0.0 0.63 9.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KEY64441.1 - 0.064 13.5 0.7 0.12 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain T2SE PF00437.15 KEY64441.1 - 0.075 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 KEY64441.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain COX4 PF02936.9 KEY64442.1 - 6.5e-49 165.3 0.0 7.3e-49 165.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Fungal_trans PF04082.13 KEY64443.1 - 7.9e-09 34.7 0.3 1.2e-08 34.1 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mus7 PF09462.5 KEY64444.1 - 1.3e-128 430.5 1.6 1.8e-128 430.1 1.1 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family Vps54 PF07928.7 KEY64444.1 - 0.16 12.1 0.6 1.5 8.9 0.0 2.7 3 0 0 3 3 3 0 Vps54-like protein ORC5_C PF14630.1 KEY64445.1 - 2.2e-82 276.6 0.0 2.6e-82 276.3 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 KEY64445.1 - 1.1e-13 51.5 2.0 5.2e-13 49.3 0.3 2.4 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 KEY64445.1 - 0.0048 15.8 0.0 0.008 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 KEY64445.1 - 0.012 15.7 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KEY64445.1 - 0.084 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family TPT PF03151.11 KEY64446.1 - 1.3e-40 138.5 1.5 1.3e-40 138.5 1.1 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KEY64446.1 - 1.5e-09 37.2 8.6 3.4e-09 36.0 6.0 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KEY64446.1 - 7.7e-07 29.1 28.0 0.00044 20.2 7.6 3.0 2 1 0 2 2 2 2 EamA-like transporter family DUF382 PF04037.8 KEY64447.1 - 1.1e-61 206.3 0.5 2.9e-61 204.9 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 KEY64447.1 - 9.2e-21 72.9 7.0 1.9e-20 71.9 4.8 1.6 1 0 0 1 1 1 1 PSP VEFS-Box PF09733.4 KEY64448.1 - 7.2e-08 32.1 0.1 7.2e-08 32.1 0.0 2.4 3 0 0 3 3 3 1 VEFS-Box of polycomb protein PHD PF00628.24 KEY64448.1 - 2.8e-05 23.7 4.6 6.9e-05 22.4 3.2 1.7 1 0 0 1 1 1 1 PHD-finger LRR_4 PF12799.2 KEY64449.1 - 0.054 13.1 6.2 2.2 7.9 1.6 4.3 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Hist_deacetyl PF00850.14 KEY64450.1 - 1.9e-89 300.0 0.0 2.8e-89 299.4 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 KEY64450.1 - 3.8e-38 130.6 0.2 6.3e-38 129.9 0.2 1.3 1 0 0 1 1 1 1 Arb2 domain F-box PF00646.28 KEY64451.1 - 1.1e-05 24.8 0.0 2.9e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KEY64451.1 - 0.0042 16.7 0.0 0.015 15.0 0.0 2.0 1 0 0 1 1 1 1 F-box-like Brix PF04427.13 KEY64452.1 - 3e-36 124.8 0.1 3.8e-36 124.5 0.1 1.1 1 0 0 1 1 1 1 Brix domain DUF739 PF05339.6 KEY64452.1 - 0.051 13.3 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF739) Ras PF00071.17 KEY64453.1 - 2.1e-63 212.5 0.2 2.5e-63 212.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEY64453.1 - 1.9e-21 76.7 0.1 2.7e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEY64453.1 - 3.9e-13 49.0 0.1 5e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KEY64453.1 - 3.1e-08 33.5 0.1 4.9e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEY64453.1 - 4.6e-05 22.9 0.1 0.00016 21.2 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KEY64453.1 - 9.8e-05 21.5 0.1 0.00017 20.8 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KEY64453.1 - 0.00012 22.2 0.1 0.00033 20.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KEY64453.1 - 0.0015 18.4 0.1 0.0034 17.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 KEY64453.1 - 0.0019 17.2 0.1 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KEY64453.1 - 0.0026 16.9 0.1 0.0062 15.7 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SpoIIID PF12116.3 KEY64453.1 - 0.0075 16.1 0.1 0.096 12.6 0.0 2.1 2 0 0 2 2 2 1 Stage III sporulation protein D SRPRB PF09439.5 KEY64453.1 - 0.012 14.8 0.0 0.024 13.8 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 KEY64453.1 - 0.016 14.7 0.1 0.051 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KEY64453.1 - 0.018 15.3 0.1 0.027 14.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 KEY64453.1 - 0.024 14.6 0.3 0.047 13.6 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 KEY64453.1 - 0.09 12.0 0.1 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 KEY64453.1 - 0.095 12.2 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 KEY64453.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Pex14_N PF04695.8 KEY64455.1 - 1.7e-16 60.4 1.7 2.4e-16 60.0 0.1 1.9 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region RecX PF02631.11 KEY64455.1 - 0.043 14.0 0.2 0.088 13.0 0.1 1.4 1 0 0 1 1 1 0 RecX family PAPA-1 PF04795.7 KEY64456.1 - 1e-25 90.2 3.0 1e-25 90.2 2.1 3.2 4 1 0 4 4 4 1 PAPA-1-like conserved region Pneumo_att_G PF05539.6 KEY64458.1 - 1.7 7.9 13.4 2.6 7.3 9.3 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF4050 PF13259.1 KEY64459.1 - 1.3e-33 115.4 0.1 5.4e-33 113.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4050) DUF2457 PF10446.4 KEY64459.1 - 0.074 11.7 12.1 0.015 14.0 5.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1180 PF06679.7 KEY64459.1 - 0.085 12.7 10.9 0.34 10.7 0.9 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1180) AMP-binding PF00501.23 KEY64460.1 - 3.4e-83 279.3 0.1 5.7e-81 272.0 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KEY64460.1 - 7.8e-61 205.5 0.0 7e-37 126.8 0.0 2.5 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KEY64460.1 - 2.4e-23 82.1 0.1 3.8e-10 39.8 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding PF00501.23 KEY64461.1 - 9e-92 307.6 0.1 1.1e-91 307.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEY64461.1 - 1.8e-11 44.8 0.0 3.6e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyr_redox PF00070.22 KEY64462.1 - 2.9e-14 53.2 2.8 5.6e-14 52.3 0.2 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEY64462.1 - 1.5e-09 38.0 0.2 0.002 18.0 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY64462.1 - 1e-07 32.2 0.1 4.2e-05 23.7 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEY64462.1 - 3.5e-05 22.8 0.4 6.6e-05 21.9 0.3 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 KEY64462.1 - 0.00011 20.9 1.3 0.055 12.0 0.5 2.8 3 0 0 3 3 3 2 Tryptophan halogenase Lycopene_cycl PF05834.7 KEY64462.1 - 0.0016 17.4 0.0 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 KEY64462.1 - 0.018 14.1 3.7 0.036 13.1 0.1 2.4 3 0 0 3 3 3 0 FAD binding domain GIDA PF01134.17 KEY64462.1 - 0.035 12.9 2.1 1.3 7.7 0.1 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A DAO PF01266.19 KEY64462.1 - 0.041 12.7 0.6 0.041 12.7 0.4 2.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KEY64462.1 - 0.11 12.2 1.6 29 4.4 0.0 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding SPX PF03105.14 KEY64463.1 - 8e-48 163.5 0.1 8e-48 163.5 0.1 1.8 2 1 0 2 2 2 1 SPX domain Acetyltransf_8 PF13523.1 KEY64463.1 - 5.8e-39 133.3 0.9 1.1e-38 132.5 0.6 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Na_sulph_symp PF00939.14 KEY64463.1 - 1.2e-35 123.2 35.0 1.7e-35 122.7 24.3 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KEY64463.1 - 1.7e-12 46.6 24.1 1.7e-12 46.6 16.7 2.6 1 1 2 3 3 3 3 Citrate transporter Acetyltransf_3 PF13302.1 KEY64463.1 - 0.056 13.6 0.2 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2207 PF09972.4 KEY64463.1 - 2.3 6.6 10.9 0.3 9.5 0.0 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) FixP_N PF14715.1 KEY64463.1 - 8.2 5.8 6.9 10 5.5 0.2 2.7 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Vps39_1 PF10366.4 KEY64464.1 - 6.1e-35 119.5 0.3 6.3e-34 116.2 0.0 2.9 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KEY64464.1 - 1.1e-27 96.3 0.0 4.6e-27 94.3 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 KEY64464.1 - 1e-18 67.7 0.0 3e-18 66.2 0.0 1.7 1 1 0 1 1 1 1 CNH domain FlaG PF03646.10 KEY64464.1 - 0.068 13.3 0.1 0.068 13.3 0.1 2.9 4 0 0 4 4 4 0 FlaG protein DUF424 PF04242.8 KEY64464.1 - 0.097 12.7 0.0 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF424) TPR_1 PF00515.23 KEY64464.1 - 0.11 12.1 8.7 2.9 7.6 0.5 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 KEY64464.1 - 0.29 11.2 9.1 0.58 10.3 0.2 3.7 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 KEY64464.1 - 1.8 8.2 7.3 55 3.5 0.2 4.4 3 1 1 4 4 4 0 TPR repeat Gon7 PF08738.5 KEY64465.1 - 3.5e-13 49.4 0.0 4.3e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Gon7 family DUF4611 PF15387.1 KEY64465.1 - 0.043 13.9 1.6 0.053 13.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) HbrB PF08539.6 KEY64466.1 - 4.1e-52 176.2 0.0 5.7e-52 175.7 0.0 1.2 1 0 0 1 1 1 1 HbrB-like TFIIA PF03153.8 KEY64466.1 - 8.6 6.1 10.7 14 5.4 7.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LIM_bind PF01803.11 KEY64467.1 - 7e-72 241.4 0.7 7e-72 241.4 0.5 5.1 2 1 2 5 5 5 1 LIM-domain binding protein Sulfotransfer_3 PF13469.1 KEY64468.1 - 1.2e-06 29.5 1.5 1.9e-06 28.9 1.1 1.4 1 1 0 1 1 1 1 Sulfotransferase family DUF1212 PF06738.7 KEY64469.1 - 1.4e-55 187.7 3.7 2.9e-52 176.9 0.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KEY64469.1 - 1.2e-21 77.0 30.5 1.5e-14 54.0 0.3 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3815) DUF2722 PF10846.3 KEY64470.1 - 5.7e-06 25.6 0.3 5.7e-06 25.6 0.2 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2722) DUF3528 PF12045.3 KEY64470.1 - 0.03 14.4 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3528) HATPase_c PF02518.21 KEY64471.1 - 3.6e-28 97.5 0.0 7.1e-28 96.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KEY64471.1 - 3.5e-20 72.1 0.1 8.6e-20 70.8 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KEY64471.1 - 1.1e-18 66.9 0.4 1.1e-18 66.9 0.3 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 KEY64471.1 - 2.9e-12 46.9 0.0 1.7e-11 44.4 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain GAF_2 PF13185.1 KEY64471.1 - 3.5e-10 40.5 0.0 9e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 KEY64471.1 - 1.3e-07 31.0 0.0 4.5e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain GAF_3 PF13492.1 KEY64471.1 - 5.5e-07 29.7 0.0 1.7e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 GAF domain Pkinase_Tyr PF07714.12 KEY64471.1 - 4.4e-05 22.6 0.0 8.7e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HATPase_c_3 PF13589.1 KEY64471.1 - 0.0029 17.2 0.0 0.0059 16.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_8 PF13181.1 KEY64471.1 - 0.0044 16.6 0.0 1 9.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat NACHT PF05729.7 KEY64471.1 - 0.08 12.5 0.3 0.88 9.2 0.0 2.5 2 1 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 KEY64471.1 - 0.089 12.9 0.1 1.7 8.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KEY64471.1 - 0.15 10.7 0.0 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 ArgK protein TPR_12 PF13424.1 KEY64471.1 - 0.54 10.2 11.2 0.17 11.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat NAD_binding_8 PF13450.1 KEY64472.1 - 3.3e-08 33.4 0.1 7.1e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KEY64472.1 - 9.9e-08 31.4 0.0 1.7e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KEY64472.1 - 0.0062 16.6 0.3 0.012 15.6 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KEY64472.1 - 0.029 14.3 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 KEY64472.1 - 0.039 13.0 0.0 0.072 12.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 KEY64472.1 - 0.046 13.5 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEY64472.1 - 0.16 11.0 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase TPT PF03151.11 KEY64473.1 - 8.6e-28 96.9 13.0 8.6e-28 96.9 9.0 2.4 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KEY64473.1 - 1.1e-07 31.0 24.3 3.2e-06 26.2 16.8 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KEY64473.1 - 4.2e-05 23.5 31.1 0.0025 17.8 7.1 2.7 3 0 0 3 3 3 2 EamA-like transporter family Ribosomal_L27e PF01777.13 KEY64474.1 - 3.2e-36 123.3 1.5 4.3e-36 122.9 1.0 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 KEY64474.1 - 0.0017 17.9 0.5 0.0042 16.7 0.4 1.7 1 0 0 1 1 1 1 KOW motif DUF3666 PF12408.3 KEY64474.1 - 0.098 11.7 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase ECM11 PF15463.1 KEY64474.1 - 0.2 11.9 0.4 0.2 11.9 0.2 1.5 2 0 0 2 2 2 0 Extracellular mutant protein 11 TPR_11 PF13414.1 KEY64475.1 - 0.0008 19.0 0.2 0.14 11.8 0.3 2.4 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.1 KEY64475.1 - 0.042 14.0 0.3 0.31 11.3 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyoxalase PF00903.20 KEY64476.1 - 2.9e-22 79.0 0.0 1.7e-15 57.1 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KEY64476.1 - 1.3e-10 41.2 0.0 0.00012 22.0 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KEY64476.1 - 1.4e-08 35.2 0.1 0.0034 17.9 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 KEY64476.1 - 0.0013 18.6 0.0 0.71 9.7 0.0 3.2 3 0 0 3 3 3 1 Glyoxalase-like domain Glyoxalase_5 PF14696.1 KEY64476.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Ssl1 PF04056.9 KEY64477.1 - 1.2e-75 253.3 0.0 1.5e-75 253.0 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 KEY64477.1 - 1.1e-16 60.5 9.4 1.1e-16 60.5 6.5 3.1 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 KEY64477.1 - 2.7e-10 40.6 0.0 4.2e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Chs3p PF12271.3 KEY64478.1 - 2.5e-102 341.8 4.6 2.9e-102 341.6 3.2 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Sugar_tr PF00083.19 KEY64479.1 - 6.3e-105 351.3 13.6 7.6e-105 351.0 9.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY64479.1 - 9.2e-29 100.2 45.2 5.2e-27 94.4 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEY64479.1 - 5.1e-05 21.8 22.3 0.0015 17.0 2.0 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 KEY64479.1 - 8.5e-05 22.2 0.4 0.0055 16.4 0.1 2.5 2 0 0 2 2 2 1 MFS_1 like family MFS_3 PF05977.8 KEY64479.1 - 0.075 11.1 3.7 0.094 10.8 0.2 2.0 2 0 0 2 2 2 0 Transmembrane secretion effector Corona_nucleoca PF00937.13 KEY64479.1 - 0.35 9.7 2.0 0.52 9.1 1.4 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Tmemb_18A PF09771.4 KEY64479.1 - 0.42 10.6 2.0 3.2 7.7 0.1 2.8 2 1 1 3 3 3 0 Transmembrane protein 188 Complex1_LYR PF05347.10 KEY64480.1 - 2.9e-05 23.7 0.4 2.9e-05 23.7 0.3 1.9 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KEY64480.1 - 5.4e-05 23.3 1.6 8.8e-05 22.6 1.1 1.6 1 1 0 1 1 1 1 Complex1_LYR-like DUF2312 PF10073.4 KEY64480.1 - 0.042 13.1 0.0 0.15 11.4 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Frataxin_Cyay PF01491.11 KEY64481.1 - 1.1e-33 115.2 0.0 1.5e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Clat_adaptor_s PF01217.15 KEY64482.1 - 1.4e-43 148.0 0.0 2.7e-43 147.0 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Metal_resist PF13801.1 KEY64483.1 - 0.21 11.5 1.1 0.79 9.7 0.3 2.0 1 1 1 2 2 2 0 Heavy-metal resistance tRNA-synt_1 PF00133.17 KEY64484.1 - 1.7e-39 135.3 0.0 5e-29 100.7 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KEY64484.1 - 4.9e-16 58.3 0.0 1e-10 40.8 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KEY64484.1 - 8.4e-11 41.8 3.5 2.7e-10 40.1 2.4 1.9 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KEY64484.1 - 2.7e-07 30.0 0.0 5.3e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain zf-CSL PF05207.8 KEY64486.1 - 6.5e-26 89.6 1.2 8.3e-26 89.2 0.8 1.2 1 0 0 1 1 1 1 CSL zinc finger TF_Zn_Ribbon PF08271.7 KEY64486.1 - 0.062 12.6 0.3 0.12 11.7 0.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding zf-RING_4 PF14570.1 KEY64486.1 - 0.089 12.3 0.4 0.15 11.6 0.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.5 KEY64486.1 - 0.21 11.5 1.8 0.41 10.6 1.2 1.5 1 1 0 1 1 1 0 Zinc ribbon domain Prok-RING_1 PF14446.1 KEY64486.1 - 1.3 8.7 3.6 3.7 7.3 2.5 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 ABC_membrane_2 PF06472.10 KEY64487.1 - 1.4e-106 355.7 2.5 1.4e-106 355.7 1.7 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KEY64487.1 - 9.1e-18 64.8 0.0 1.9e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KEY64487.1 - 0.0008 19.4 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEY64487.1 - 0.013 15.5 0.1 0.057 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 KEY64487.1 - 0.047 13.2 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KEY64487.1 - 0.068 13.4 0.2 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KEY64487.1 - 0.077 12.2 0.0 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.16 KEY64487.1 - 0.1 11.7 0.1 0.51 9.4 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 KEY64487.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IBR PF01485.16 KEY64488.1 - 1.5e-10 40.7 1.5 1.5e-10 40.7 1.1 3.7 3 1 0 3 3 3 1 IBR domain zf-C3HC4_3 PF13920.1 KEY64488.1 - 0.059 13.0 18.5 0.021 14.4 2.3 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.1 KEY64488.1 - 0.16 11.1 4.5 6.6 6.0 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 KEY64488.1 - 0.29 10.9 4.8 1.5 8.6 0.8 3.3 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zf-C3HC4_2 PF13923.1 KEY64488.1 - 0.77 9.8 20.4 0.49 10.4 4.4 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.4 KEY64488.1 - 1.3 8.7 8.0 29 4.4 0.1 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Zn-ribbon_8 PF09723.5 KEY64488.1 - 3.6 7.6 11.3 9.9 6.2 1.3 3.7 3 0 0 3 3 3 0 Zinc ribbon domain OmpH PF03938.9 KEY64488.1 - 5.9 6.8 11.4 10 6.0 7.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Mnd1 PF03962.10 KEY64489.1 - 0.072 12.7 2.3 0.14 11.8 1.6 1.5 1 0 0 1 1 1 0 Mnd1 family DUF837 PF05769.6 KEY64489.1 - 0.18 11.3 4.2 0.33 10.4 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF837) DUF2968 PF11180.3 KEY64489.1 - 0.4 10.0 4.0 0.73 9.1 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DivIVA PF05103.8 KEY64489.1 - 5.9 6.9 8.0 1.1 9.3 0.4 2.7 2 1 0 3 3 3 0 DivIVA protein HSP70 PF00012.15 KEY64490.1 - 4.3e-13 48.0 0.0 8.1e-11 40.5 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein BcrAD_BadFG PF01869.15 KEY64490.1 - 0.079 12.2 0.4 0.25 10.5 0.0 2.0 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family DUF1693 PF07984.7 KEY64490.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1693) DOCK-C2 PF14429.1 KEY64491.1 - 3.5e-21 75.6 0.0 6.9e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 KEY64491.1 - 9.3e-11 41.3 0.0 2.7e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 KEY64491.1 - 3.1e-05 23.2 0.0 6.8e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KEY64491.1 - 0.0005 19.5 0.0 0.0033 16.9 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KEY64491.1 - 0.067 12.7 0.0 0.2 11.1 0.0 1.9 1 1 0 1 1 1 0 Variant SH3 domain Acetyltransf_1 PF00583.19 KEY64492.1 - 1e-05 25.4 0.1 2.6e-05 24.1 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.1 KEY64492.1 - 0.00057 20.4 0.1 0.046 14.3 0.0 2.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KEY64492.1 - 0.0021 18.1 0.0 0.0051 16.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_S7 PF00177.16 KEY64493.1 - 3e-40 137.1 1.6 3.9e-40 136.8 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S25 PF03297.10 KEY64494.1 - 1.3e-40 137.6 5.1 1.4e-40 137.5 3.5 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 KEY64494.1 - 0.0034 16.7 0.1 0.005 16.2 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 KEY64494.1 - 0.024 14.2 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 MarR family DUF1744 PF08490.7 KEY64494.1 - 0.048 12.2 0.0 0.052 12.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) Mito_carr PF00153.22 KEY64495.1 - 6.3e-65 214.9 4.6 3.9e-23 80.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CENP-X PF09415.5 KEY64496.1 - 5.2e-26 90.2 0.1 9.3e-26 89.4 0.0 1.4 1 0 0 1 1 1 1 CENP-S associating Centromere protein X AT_hook PF02178.14 KEY64496.1 - 0.016 14.7 2.6 0.032 13.8 1.8 1.5 1 0 0 1 1 1 0 AT hook motif Cyt-b5 PF00173.23 KEY64499.1 - 8.2e-11 41.5 0.0 1.4e-10 40.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BTB_2 PF02214.17 KEY64501.1 - 6.1e-06 26.3 0.1 0.0035 17.4 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Rep_fac_C PF08542.6 KEY64502.1 - 1.1e-16 60.5 0.1 2.8e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 KEY64502.1 - 3.9e-15 56.2 0.0 7.9e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KEY64502.1 - 8.6e-13 48.2 0.2 2.9e-12 46.5 0.0 2.0 2 1 0 2 2 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KEY64502.1 - 1e-09 37.6 0.0 3.5e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KEY64502.1 - 1.6e-06 28.2 0.0 2e-05 24.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KEY64502.1 - 5e-06 25.7 0.0 6e-05 22.1 0.0 2.2 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KEY64502.1 - 1.4e-05 24.7 0.0 0.00012 21.7 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain DNA_pol3_delta PF06144.8 KEY64502.1 - 2.4e-05 23.9 0.0 4.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit TIP49 PF06068.8 KEY64502.1 - 2.5e-05 23.1 0.0 0.058 12.0 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_16 PF13191.1 KEY64502.1 - 3.2e-05 23.9 0.1 0.0019 18.2 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_11 PF13086.1 KEY64502.1 - 5.8e-05 22.7 0.1 0.00062 19.4 0.0 2.2 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KEY64502.1 - 0.00044 19.9 0.1 0.0016 18.1 0.1 2.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KEY64502.1 - 0.00045 19.8 0.0 0.00085 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KEY64502.1 - 0.00048 20.0 0.0 0.00095 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KEY64502.1 - 0.00069 19.2 0.4 0.0041 16.7 0.1 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KEY64502.1 - 0.0015 17.5 0.0 0.0026 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 KEY64502.1 - 0.0066 15.6 0.1 0.039 13.0 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KEY64502.1 - 0.01 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEY64502.1 - 0.011 16.0 0.1 0.042 14.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.1 KEY64502.1 - 0.013 14.8 0.0 0.047 13.0 0.0 2.0 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 KEY64502.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KEY64502.1 - 0.014 14.6 0.6 3.7 6.7 0.0 2.5 1 1 0 2 2 2 0 PhoH-like protein AAA_17 PF13207.1 KEY64502.1 - 0.015 16.0 0.1 0.041 14.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain DEAD PF00270.24 KEY64502.1 - 0.027 13.9 0.2 0.4 10.1 0.0 2.4 2 1 1 3 3 3 0 DEAD/DEAH box helicase ResIII PF04851.10 KEY64502.1 - 0.029 14.1 0.0 0.074 12.8 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MCM PF00493.18 KEY64502.1 - 0.054 12.2 0.0 0.12 11.1 0.0 1.5 1 0 0 1 1 1 0 MCM2/3/5 family AAA_10 PF12846.2 KEY64502.1 - 0.066 12.6 0.1 3.3 7.0 0.0 2.3 1 1 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 KEY64502.1 - 0.097 12.0 0.0 0.59 9.5 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein BLOC1_2 PF10046.4 KEY64502.1 - 0.1 12.7 0.0 0.31 11.2 0.0 1.7 2 0 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RNA_helicase PF00910.17 KEY64502.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.6 1 1 0 1 1 1 0 RNA helicase PAP2 PF01569.16 KEY64503.1 - 1.2e-16 60.6 3.7 3.4e-16 59.0 2.5 1.8 1 0 0 1 1 1 1 PAP2 superfamily adh_short PF00106.20 KEY64504.1 - 4.2e-29 101.5 0.4 6.4e-29 101.0 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY64504.1 - 8.8e-23 81.3 0.0 1.1e-22 80.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY64504.1 - 2.8e-11 43.4 0.3 4e-11 42.9 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY64504.1 - 1.7e-07 30.9 0.1 1.4e-06 27.8 0.0 2.0 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KEY64504.1 - 0.0037 16.1 0.0 0.0045 15.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KEY64504.1 - 0.0046 15.9 0.0 0.0059 15.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KEY64504.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.1 KEY64504.1 - 0.026 14.5 0.7 0.047 13.7 0.5 1.5 1 1 0 1 1 1 0 NADH(P)-binding NAD_binding_2 PF03446.10 KEY64504.1 - 0.029 14.2 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.12 KEY64504.1 - 0.035 13.0 0.0 0.062 12.1 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain 3HCDH_N PF02737.13 KEY64504.1 - 0.058 13.0 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 KEY64505.1 - 6.8e-42 142.5 0.1 1.5e-41 141.3 0.1 1.6 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 KEY64505.1 - 2.2e-29 100.8 0.3 5.8e-29 99.4 0.2 1.8 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KEY64505.1 - 2.6e-20 71.5 1.5 2.6e-20 71.5 1.0 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 KEY64505.1 - 2.7e-16 59.4 2.6 7.7e-16 57.9 0.6 2.2 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 KEY64505.1 - 0.00064 19.8 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KEY64505.1 - 0.0009 19.4 0.0 0.0028 17.8 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.22 KEY64505.1 - 0.0038 17.6 0.1 1.1 9.7 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Glyco_transf_34 PF05637.7 KEY64506.1 - 1.7e-63 214.3 0.2 2.3e-63 213.9 0.1 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family MAPEG PF01124.13 KEY64506.1 - 1.3e-11 44.1 0.4 1.3e-11 44.1 0.2 2.0 2 0 0 2 2 2 1 MAPEG family Rb_C PF08934.5 KEY64506.1 - 0.11 12.1 2.2 0.2 11.3 1.5 1.3 1 0 0 1 1 1 0 Rb C-terminal domain Peptidase_M22 PF00814.20 KEY64507.1 - 7.8e-47 160.0 0.1 1.8e-26 93.2 0.8 2.6 1 1 1 2 2 2 2 Glycoprotease family Herpes_US9 PF06072.6 KEY64507.1 - 0.47 10.3 5.3 1.1 9.0 1.1 2.6 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 MutL_C PF08676.6 KEY64508.1 - 1.4e-21 76.5 0.0 2.7e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 KEY64508.1 - 5.2e-18 64.6 0.0 2e-17 62.7 0.0 2.0 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KEY64508.1 - 4.4e-13 49.0 0.0 9.6e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KEY64508.1 - 5.1e-11 42.2 0.0 1.1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pyr_redox_2 PF07992.9 KEY64510.1 - 2.4e-08 34.1 0.0 5.3e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY64510.1 - 0.00014 22.0 0.1 0.015 15.3 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY64510.1 - 0.012 15.6 0.0 0.034 14.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TetR_C_5 PF08360.6 KEY64510.1 - 0.095 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 QacR-like protein, C-terminal region ETF PF01012.16 KEY64511.1 - 1.4e-41 142.0 1.0 2.4e-41 141.1 0.7 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 KEY64511.1 - 5.8e-36 121.9 0.3 1.2e-35 121.0 0.2 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain SWIRM PF04433.12 KEY64512.1 - 1.4e-34 118.0 0.1 2.5e-34 117.2 0.1 1.4 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 KEY64512.1 - 7.7e-06 25.3 4.8 1.5e-05 24.3 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 KEY64512.1 - 6.4e-05 22.9 0.1 0.00015 21.7 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Carn_acyltransf PF00755.15 KEY64513.1 - 7.1e-180 598.9 0.0 8.1e-180 598.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CAP_N PF01213.14 KEY64514.1 - 5.1e-98 328.2 0.3 7.3e-98 327.6 0.2 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 KEY64514.1 - 2.5e-53 179.6 1.4 3.4e-53 179.2 0.9 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 KEY64514.1 - 0.063 12.6 0.8 0.35 10.2 0.4 1.9 1 1 1 2 2 2 0 Tubulin binding cofactor C Ribosomal_60s PF00428.14 KEY64514.1 - 0.19 12.1 8.1 4.2 7.8 0.2 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein PfkB PF00294.19 KEY64515.1 - 3.8e-14 52.5 0.0 1.3e-08 34.3 0.1 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase MCM PF00493.18 KEY64516.1 - 4.5e-129 429.9 1.0 6.8e-129 429.4 0.7 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KEY64516.1 - 8.1e-19 68.2 0.1 5.1e-18 65.7 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KEY64516.1 - 3e-07 29.8 0.0 3.6e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KEY64516.1 - 0.0062 16.1 0.0 0.017 14.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KEY64516.1 - 0.013 15.0 0.0 0.04 13.4 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Exo70 PF03081.10 KEY64517.1 - 1.8e-71 240.8 0.0 2.9e-71 240.2 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Baculo_PEP_C PF04513.7 KEY64517.1 - 0.0088 15.8 9.9 1.3 8.8 0.6 3.6 3 0 0 3 3 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus Nnf1 PF03980.9 KEY64517.1 - 0.029 14.3 3.4 0.13 12.2 0.3 3.2 3 0 0 3 3 3 0 Nnf1 Apolipoprotein PF01442.13 KEY64517.1 - 1.8 8.0 7.9 0.38 10.2 0.2 3.3 4 0 0 4 4 4 0 Apolipoprotein A1/A4/E domain ADH_N PF08240.7 KEY64518.1 - 1.3e-23 82.8 4.8 2e-23 82.2 3.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY64518.1 - 1e-18 67.0 0.0 1.7e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY64518.1 - 0.0034 18.2 0.0 0.0055 17.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KEY64518.1 - 0.012 14.7 0.1 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4241 PF14025.1 KEY64518.1 - 0.054 13.2 0.1 0.093 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) EHN PF06441.7 KEY64519.1 - 3.9e-35 120.1 1.6 3.9e-34 116.9 0.1 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KEY64519.1 - 7.8e-12 45.5 0.2 1.6e-11 44.5 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY64519.1 - 1.8e-08 34.2 0.0 2.7e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Fungal_trans_2 PF11951.3 KEY64520.1 - 0.00027 19.6 0.5 0.00031 19.4 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY64520.1 - 0.00057 19.7 4.0 0.00091 19.0 2.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.1 KEY64521.1 - 1.9e-08 34.5 0.0 2.7e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 KEY64521.1 - 0.02 14.7 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 KEY64521.1 - 0.034 12.8 0.0 0.046 12.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family zf-CCCH PF00642.19 KEY64522.1 - 0.00025 20.6 12.8 0.025 14.2 0.6 3.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) EthD PF07110.6 KEY64523.1 - 0.05 14.5 0.0 0.22 12.4 0.0 1.8 1 1 0 1 1 1 0 EthD domain Ring_hydroxyl_A PF00848.14 KEY64524.1 - 3.9e-36 124.6 5.3 2.2e-35 122.2 3.7 2.0 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 KEY64524.1 - 3.1e-17 61.9 0.1 5.5e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CorC_HlyC PF03471.12 KEY64524.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 Transporter associated domain DAO PF01266.19 KEY64525.1 - 3.1e-44 151.3 0.1 5.3e-44 150.5 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fungal_trans PF04082.13 KEY64525.1 - 1.3e-10 40.5 0.7 2.1e-10 39.9 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_9 PF13454.1 KEY64525.1 - 9.5e-07 28.7 1.3 0.021 14.6 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KEY64525.1 - 9.7e-06 25.7 0.1 0.0046 17.0 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEY64525.1 - 3.7e-05 23.6 0.1 0.03 14.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KEY64525.1 - 4.7e-05 22.1 0.0 0.0007 18.3 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.17 KEY64525.1 - 0.001 18.0 0.1 0.003 16.4 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KEY64525.1 - 0.0076 16.2 0.0 0.023 14.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KEY64525.1 - 0.051 12.4 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.19 KEY64526.1 - 8.4e-58 195.9 0.2 1.2e-57 195.4 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.16 KEY64526.1 - 1e-45 155.6 0.0 1.5e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KEY64526.1 - 1.7e-15 56.7 0.0 4.3e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox_3 PF13738.1 KEY64526.1 - 1.4e-06 28.4 0.0 4.8e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY64526.1 - 9.2e-05 22.7 0.8 0.0053 17.1 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEY64526.1 - 0.00017 20.5 0.0 0.00031 19.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain SoxG PF04268.7 KEY64526.1 - 0.00055 19.8 0.0 0.025 14.4 0.0 2.7 2 0 0 2 2 2 1 Sarcosine oxidase, gamma subunit family ThiF PF00899.16 KEY64526.1 - 0.00067 19.4 0.0 0.0016 18.2 0.0 1.7 1 0 0 1 1 1 1 ThiF family NAD_binding_9 PF13454.1 KEY64526.1 - 0.0061 16.3 0.3 0.24 11.1 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding TrkA_N PF02254.13 KEY64526.1 - 0.0078 16.2 0.9 0.026 14.5 0.2 2.1 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_8 PF13450.1 KEY64526.1 - 0.012 15.6 0.0 0.045 13.7 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KEY64526.1 - 0.023 13.1 0.4 0.32 9.3 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 KEY64526.1 - 0.032 14.1 0.0 0.073 12.9 0.0 1.6 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KEY64526.1 - 0.066 11.8 1.2 1.3 7.5 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.15 KEY64526.1 - 0.079 13.0 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 KEY64526.1 - 0.11 11.5 0.1 0.61 9.0 0.2 2.0 3 0 0 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.7 KEY64526.1 - 0.19 10.6 0.1 0.78 8.5 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 KEY64526.1 - 0.32 10.6 0.4 0.6 9.7 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M20 PF01546.23 KEY64527.1 - 5.1e-10 39.1 0.3 9.4e-10 38.2 0.1 1.5 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KEY64527.1 - 1.1e-05 25.0 0.2 2.5e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain FCD PF07729.7 KEY64527.1 - 0.011 16.0 0.0 0.43 10.9 0.0 2.4 1 1 1 2 2 2 0 FCD domain YbfN PF13982.1 KEY64528.1 - 0.0054 16.8 0.2 0.0097 16.0 0.1 1.3 1 0 0 1 1 1 1 YbfN-like lipoprotein 2OG-FeII_Oxy PF03171.15 KEY64529.1 - 3.7e-14 52.8 0.0 8.3e-14 51.6 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KEY64529.1 - 4.8e-10 39.9 0.0 8e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Abhydrolase_1 PF00561.15 KEY64530.1 - 1.4e-11 44.3 0.3 6e-11 42.3 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEY64530.1 - 1.6e-09 37.9 0.0 3.9e-09 36.7 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KEY64530.1 - 7.3e-06 25.8 0.0 5.6e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_5 PF12695.2 KEY64530.1 - 0.00053 19.7 0.0 0.0078 15.9 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Ndr PF03096.9 KEY64530.1 - 0.0034 15.9 0.0 0.098 11.1 0.0 2.2 2 0 0 2 2 2 1 Ndr family Fungal_trans_2 PF11951.3 KEY64531.1 - 6.7e-06 24.9 0.5 0.00015 20.5 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY64531.1 - 0.0018 18.1 2.9 0.0018 18.1 2.0 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA-synt_1c PF00749.16 KEY64532.1 - 6e-94 314.2 0.0 1.2e-93 313.2 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KEY64532.1 - 7.4e-34 116.9 0.0 7.9e-33 113.5 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 KEY64532.1 - 0.00016 22.0 0.0 0.0004 20.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Fungal_trans PF04082.13 KEY64533.1 - 0.00021 20.2 0.1 0.01 14.7 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Fcf1 PF04900.7 KEY64533.1 - 0.03 14.4 0.2 10 6.2 0.0 3.5 3 0 0 3 3 3 0 Fcf1 AA_permease_2 PF13520.1 KEY64534.1 - 2.1e-31 108.9 44.8 2.7e-31 108.5 31.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEY64534.1 - 1.1e-13 50.4 33.5 1.4e-13 49.9 23.2 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0182 PF03699.8 KEY64534.1 - 0.00049 18.1 0.4 0.00074 17.5 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0182) MFS_1 PF07690.11 KEY64535.1 - 2.4e-23 82.4 35.1 2.5e-23 82.3 23.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily ABM PF03992.11 KEY64536.1 - 0.00027 20.9 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase MHCassoc_trimer PF08831.5 KEY64536.1 - 0.082 12.7 0.0 0.96 9.3 0.0 2.0 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain MatE PF01554.13 KEY64537.1 - 5.4e-46 156.1 29.5 2.2e-24 85.8 6.6 2.3 2 0 0 2 2 2 2 MatE Arginase PF00491.16 KEY64538.1 - 1e-80 271.0 0.2 1.3e-80 270.7 0.2 1.0 1 0 0 1 1 1 1 Arginase family Ribonuc_L-PSP PF01042.16 KEY64539.1 - 6.1e-18 64.7 0.0 9.1e-17 60.9 0.0 2.0 1 1 0 1 1 1 1 Endoribonuclease L-PSP Peripla_BP_6 PF13458.1 KEY64539.1 - 0.028 13.7 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein p450 PF00067.17 KEY64540.1 - 7.6e-54 182.9 0.0 1.1e-53 182.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KEY64541.1 - 1.9e-34 118.9 25.8 1.9e-34 118.9 17.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily RhodobacterPufX PF11511.3 KEY64541.1 - 0.04 13.3 2.0 6.2 6.2 0.1 3.0 2 0 0 2 2 2 0 Intrinsic membrane protein PufX Fungal_trans PF04082.13 KEY64542.1 - 5.2e-24 84.5 0.0 8.4e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Asp_Glu_race PF01177.17 KEY64542.1 - 2.3e-10 40.7 0.0 4.7e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Zn_clus PF00172.13 KEY64542.1 - 0.0005 19.9 7.0 0.0011 18.8 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M28 PF04389.12 KEY64543.1 - 1.3e-30 106.4 0.2 2.3e-30 105.6 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KEY64543.1 - 0.0019 17.7 0.3 0.0036 16.8 0.1 1.6 1 1 1 2 2 2 1 Peptidase family M20/M25/M40 Oxidored_FMN PF00724.15 KEY64544.1 - 8.9e-89 297.8 0.0 1e-88 297.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.11 KEY64545.1 - 1.9e-44 151.8 51.6 2.2e-43 148.3 35.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KEY64545.1 - 6.5e-18 64.2 16.0 7.2e-18 64.1 10.5 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KEY64545.1 - 1.3e-14 53.7 11.1 1.3e-14 53.7 7.7 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 KEY64545.1 - 0.001 17.5 5.2 0.001 17.5 3.6 3.2 1 1 3 4 4 4 2 MFS/sugar transport protein Polysacc_deac_1 PF01522.16 KEY64546.1 - 1.9e-13 50.1 0.0 3.2e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Fungal_trans PF04082.13 KEY64547.1 - 3.9e-29 101.3 0.0 6.9e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ACP_syn_III_C PF08541.5 KEY64547.1 - 0.11 12.4 0.0 9.8 6.2 0.0 2.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Transp_cyt_pur PF02133.10 KEY64548.1 - 8.4e-83 278.3 37.7 1.1e-82 277.9 26.1 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidase PF01425.16 KEY64548.1 - 2.5e-68 230.9 0.3 3.5e-68 230.4 0.2 1.2 1 0 0 1 1 1 1 Amidase DUF3040 PF11239.3 KEY64548.1 - 0.21 11.6 1.5 3.4 7.7 0.0 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) Sugar_tr PF00083.19 KEY64549.1 - 9.5e-68 228.8 24.8 1.1e-67 228.6 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY64549.1 - 4.5e-07 28.9 17.8 4.5e-07 28.9 12.3 2.6 1 1 0 2 2 2 2 Major Facilitator Superfamily Raffinose_syn PF05691.7 KEY64550.1 - 1.7e-55 187.9 0.1 4.4e-41 140.2 0.0 3.1 2 1 0 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 KEY64550.1 - 0.00012 20.9 0.1 0.00023 19.9 0.1 1.4 1 1 0 1 1 1 1 Melibiase adh_short PF00106.20 KEY64551.1 - 4.8e-06 26.5 0.2 9.3e-06 25.6 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY64551.1 - 0.021 14.5 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 KR domain adh_short_C2 PF13561.1 KEY64551.1 - 0.029 14.1 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Fungal_trans PF04082.13 KEY64552.1 - 3.7e-13 48.9 0.1 6.2e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HSBP1 PF06825.7 KEY64552.1 - 0.16 11.5 0.1 0.34 10.5 0.1 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 adh_short PF00106.20 KEY64553.1 - 1.3e-16 60.9 0.4 4.5e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY64553.1 - 1.8e-09 37.4 0.0 3.1e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY64553.1 - 6.2e-06 25.8 0.0 1.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KEY64553.1 - 0.00031 19.7 0.0 0.00042 19.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 KEY64553.1 - 0.0075 15.2 0.1 0.021 13.7 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KEY64553.1 - 0.011 15.7 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KEY64553.1 - 0.023 14.6 0.2 0.047 13.6 0.0 1.6 2 0 0 2 2 2 0 NADH(P)-binding 3Beta_HSD PF01073.14 KEY64553.1 - 0.04 12.6 0.0 0.055 12.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KEY64553.1 - 0.091 12.6 0.1 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 KEY64553.1 - 0.1 11.4 0.0 0.2 10.5 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.1 KEY64554.1 - 1e-11 45.2 0.0 1.2e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Gin PF10764.4 KEY64555.1 - 0.07 12.8 0.5 0.11 12.2 0.3 1.3 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin HET PF06985.6 KEY64556.1 - 2e-25 89.5 0.0 3.5e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.13 KEY64557.1 - 4.2e-16 58.5 0.6 7.6e-16 57.7 0.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain UPF0075 PF03702.9 KEY64558.1 - 6.1e-76 255.6 0.0 5.3e-73 246.0 0.0 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0075) Sugar_tr PF00083.19 KEY64560.1 - 9.3e-75 251.9 27.2 1.1e-74 251.7 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY64560.1 - 4.1e-18 65.2 23.9 4.1e-18 65.2 16.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 KEY64560.1 - 0.057 13.4 0.7 0.057 13.4 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Pilin_PilA PF14245.1 KEY64560.1 - 0.16 12.5 0.7 0.34 11.4 0.5 1.6 1 0 0 1 1 1 0 Type IV pilin PilA Transaldolase PF00923.14 KEY64561.1 - 3.7e-74 249.4 1.2 4.2e-74 249.2 0.8 1.0 1 0 0 1 1 1 1 Transaldolase RNase_Zc3h12a PF11977.3 KEY64561.1 - 0.067 13.0 0.0 0.14 11.9 0.0 1.5 2 0 0 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain Ebola_NP PF05505.7 KEY64561.1 - 0.072 11.1 0.0 0.091 10.8 0.0 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein DAO PF01266.19 KEY64563.1 - 3.8e-45 154.3 4.0 4.3e-45 154.1 2.8 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEY64563.1 - 3.8e-07 30.1 0.2 2.6e-05 24.2 0.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEY64563.1 - 2.1e-05 24.3 1.7 0.052 13.3 0.3 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.17 KEY64563.1 - 0.00017 20.5 2.8 0.1 11.4 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KEY64563.1 - 0.00032 19.6 1.0 0.027 13.3 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KEY64563.1 - 0.00075 18.5 2.8 0.0024 16.8 0.2 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 KEY64563.1 - 0.00078 18.6 1.4 0.01 14.9 0.2 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 KEY64563.1 - 0.0021 18.0 1.6 0.0021 18.0 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 KEY64563.1 - 0.023 14.3 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 KEY64563.1 - 0.036 14.1 0.7 0.56 10.2 0.5 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KEY64563.1 - 0.05 13.0 1.3 0.11 11.9 0.9 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 KEY64563.1 - 0.087 11.8 3.2 0.84 8.6 0.3 2.3 2 1 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.1 KEY64563.1 - 0.1 12.8 0.0 0.3 11.3 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.9 KEY64563.1 - 0.27 9.8 7.1 1.1 7.8 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase ThiF PF00899.16 KEY64563.1 - 0.28 10.9 1.8 1.3 8.8 0.2 2.2 2 0 0 2 2 2 0 ThiF family DinB_2 PF12867.2 KEY64563.1 - 2 8.7 5.0 3 8.1 2.1 2.2 2 1 0 2 2 2 0 DinB superfamily Glyco_hydro_18 PF00704.23 KEY64565.1 - 3.8e-73 246.8 0.0 8.7e-73 245.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KEY64565.1 - 7.1e-11 41.9 15.2 7.1e-11 41.9 10.5 4.2 3 0 0 3 3 3 2 Chitin recognition protein LysM PF01476.15 KEY64566.1 - 1.8e-25 88.5 1.0 3.7e-05 23.5 0.1 5.3 5 0 0 5 5 5 5 LysM domain DUF202 PF02656.10 KEY64567.1 - 5.3e-21 74.6 0.1 1.3e-20 73.3 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF3483 PF11982.3 KEY64567.1 - 0.014 14.6 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) DUF2370 PF10176.4 KEY64567.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Glyco_transf_54 PF04666.8 KEY64568.1 - 1.7e-15 56.5 0.0 8e-14 51.0 0.0 2.7 2 1 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region CBM_1 PF00734.13 KEY64569.1 - 3.3e-10 39.4 14.2 3.3e-10 39.4 9.9 2.7 2 0 0 2 2 2 1 Fungal cellulose binding domain Abhydrolase_5 PF12695.2 KEY64569.1 - 1.8e-05 24.5 0.1 3.6e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY64569.1 - 0.00053 19.9 0.3 0.00075 19.4 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEY64569.1 - 0.00054 19.2 0.4 0.001 18.3 0.3 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KEY64569.1 - 0.008 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.15 KEY64569.1 - 0.084 12.2 1.4 0.3 10.4 1.0 2.0 1 1 0 1 1 1 0 Putative esterase Conotoxin PF02950.12 KEY64569.1 - 0.18 12.5 2.8 0.32 11.8 1.9 1.4 1 0 0 1 1 1 0 Conotoxin Toxin_7 PF05980.7 KEY64569.1 - 0.91 9.6 12.8 0.27 11.2 6.0 2.2 2 0 0 2 2 2 0 Toxin 7 Glyco_hydro_18 PF00704.23 KEY64570.1 - 1e-93 314.5 2.8 1.2e-93 314.3 2.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PAN_4 PF14295.1 KEY64571.1 - 4.5e-05 23.0 14.3 0.0024 17.5 0.4 3.2 3 0 0 3 3 3 2 PAN domain MANEC PF07502.9 KEY64571.1 - 0.0015 18.4 5.4 0.36 10.8 0.9 2.5 2 0 0 2 2 2 2 MANEC domain p450 PF00067.17 KEY64572.1 - 2.8e-52 177.7 0.0 3.7e-52 177.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Esterase_phd PF10503.4 KEY64573.1 - 6.6e-23 81.0 0.2 1e-22 80.5 0.1 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KEY64573.1 - 9.8e-13 47.8 0.1 1.5e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family CBM_1 PF00734.13 KEY64573.1 - 2.2e-10 40.0 12.1 2.2e-10 40.0 8.4 3.2 3 0 0 3 3 3 1 Fungal cellulose binding domain Abhydrolase_5 PF12695.2 KEY64573.1 - 1.3e-07 31.4 0.1 2.1e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY64573.1 - 0.00017 21.5 0.2 0.00028 20.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KEY64573.1 - 0.00051 19.5 0.1 0.0019 17.6 0.1 1.9 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.15 KEY64573.1 - 0.0025 17.2 0.8 0.019 14.4 0.5 2.0 1 1 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 KEY64573.1 - 0.0088 15.6 0.1 0.013 15.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KEY64573.1 - 0.012 15.1 0.1 0.023 14.2 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Toxin_7 PF05980.7 KEY64573.1 - 0.019 14.9 8.3 0.019 14.9 5.8 2.1 2 0 0 2 2 2 0 Toxin 7 COesterase PF00135.23 KEY64573.1 - 0.039 12.6 0.5 0.061 12.0 0.3 1.3 1 0 0 1 1 1 0 Carboxylesterase family DLH PF01738.13 KEY64573.1 - 0.37 10.0 1.6 0.66 9.2 1.1 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family Alpha-amylase PF00128.19 KEY64575.1 - 1.5e-92 310.3 0.5 1.5e-92 310.3 0.4 1.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KEY64575.1 - 0.0047 15.8 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GHL6 PF14871.1 KEY64575.1 - 0.073 13.0 0.2 0.51 10.3 0.0 2.2 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Glyco_hydro_32N PF00251.15 KEY64576.1 - 1.5e-45 155.9 0.0 2.1e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.9 KEY64576.1 - 0.0063 15.6 0.1 2.2 7.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_32C PF08244.7 KEY64576.1 - 0.068 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 KEY64576.1 - 0.071 12.9 4.3 0.39 10.7 0.0 4.2 5 0 0 5 5 5 0 BNR/Asp-box repeat Sugar_tr PF00083.19 KEY64577.1 - 1.4e-70 238.1 22.3 1.6e-70 237.9 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY64577.1 - 5.7e-20 71.3 37.2 1.1e-18 67.0 20.5 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily Fungal_trans PF04082.13 KEY64578.1 - 1.3e-10 40.6 2.7 2.5e-10 39.6 1.9 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY64578.1 - 8.1e-08 32.0 7.2 1.4e-07 31.2 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3810 PF12725.2 KEY64579.1 - 0.074 11.9 0.1 0.15 10.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) PHBC_N PF12551.3 KEY64579.1 - 0.59 9.7 8.9 3.4 7.2 0.4 3.3 3 0 0 3 3 3 0 Poly-beta-hydroxybutyrate polymerase N terminal FAD_binding_4 PF01565.18 KEY64581.1 - 2.4e-06 27.0 0.0 4.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.11 KEY64584.1 - 6.2e-43 146.8 35.9 6.2e-43 146.8 24.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY64584.1 - 1.3e-11 43.7 12.3 1.3e-11 43.7 8.5 2.6 2 1 0 3 3 3 1 Sugar (and other) transporter NDUF_B12 PF08122.7 KEY64584.1 - 0.61 9.8 3.5 22 4.8 0.0 3.3 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Fungal_trans_2 PF11951.3 KEY64585.1 - 0.0054 15.3 0.0 0.011 14.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 KEY64586.1 - 8.8e-16 58.2 0.0 1.4e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY64586.1 - 5.3e-09 35.9 0.1 8.3e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY64586.1 - 0.00029 20.6 0.0 0.00041 20.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Myb_DNA-binding PF00249.26 KEY64587.1 - 4.1e-23 81.1 0.7 3.4e-12 46.2 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEY64587.1 - 4e-20 71.6 2.2 1.5e-09 37.8 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 KEY64587.1 - 0.038 13.8 0.1 7.4 6.4 0.0 2.8 2 1 0 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_5 PF13873.1 KEY64587.1 - 0.86 9.5 3.9 5.7 6.9 0.2 3.2 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 KEY64587.1 - 1 9.2 3.1 62 3.5 2.2 2.8 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.1 KEY64587.1 - 1.5 8.9 5.5 12 6.0 0.4 3.1 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain NOA36 PF06524.7 KEY64587.1 - 2 7.6 5.2 2.8 7.1 3.6 1.1 1 0 0 1 1 1 0 NOA36 protein p450 PF00067.17 KEY64588.1 - 5.3e-54 183.4 0.0 7.8e-52 176.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 KEY64589.1 - 3e-75 252.9 0.7 1.2e-74 250.9 0.2 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KEY64589.1 - 1.1e-29 102.7 2.1 3.6e-19 68.7 0.0 3.0 3 0 0 3 3 3 2 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KEY64589.1 - 3.2e-28 99.0 0.0 1.8e-27 96.5 0.0 2.1 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 KEY64589.1 - 1.1e-20 74.0 0.0 2e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 KEY64589.1 - 2.2e-17 63.3 0.0 7e-17 61.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.8 KEY64589.1 - 3.1e-14 53.0 0.0 1.2e-13 51.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_23 PF13489.1 KEY64589.1 - 7.7e-12 45.2 0.1 5.1e-10 39.2 0.0 3.3 3 0 0 3 3 3 1 Methyltransferase domain Abhydrolase_6 PF12697.2 KEY64589.1 - 8e-10 38.9 1.1 1.1e-08 35.2 0.2 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family PP-binding PF00550.20 KEY64589.1 - 1e-09 38.5 0.7 2.2e-09 37.4 0.5 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 KEY64589.1 - 2.7e-09 36.7 0.0 7.2e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_5 PF12695.2 KEY64589.1 - 1.2e-08 34.8 0.1 8.2e-07 28.8 0.0 3.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family Methyltransf_11 PF08241.7 KEY64589.1 - 3.8e-08 33.7 0.0 2.1e-07 31.3 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY64589.1 - 1.4e-06 28.8 0.0 1.7e-05 25.3 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain Thiolase_N PF00108.18 KEY64589.1 - 2e-05 23.7 0.1 3.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.1 KEY64589.1 - 8.4e-05 22.8 0.0 0.00029 21.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S9 PF00326.16 KEY64589.1 - 0.00011 21.5 0.0 0.028 13.6 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family MTS PF05175.9 KEY64589.1 - 0.003 16.9 0.0 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KEY64589.1 - 0.0037 16.4 0.0 0.034 13.2 0.0 2.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 KEY64589.1 - 0.0071 15.8 0.0 0.021 14.2 0.0 1.8 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_28 PF02636.12 KEY64589.1 - 0.008 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase COesterase PF00135.23 KEY64589.1 - 0.13 10.9 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family NodS PF05401.6 KEY64589.1 - 0.16 11.3 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) DREV PF05219.7 KEY64589.1 - 0.34 9.7 0.0 0.59 8.9 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Lactamase_B PF00753.22 KEY64590.1 - 1.6e-09 37.6 0.3 3.3e-09 36.6 0.2 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KEY64590.1 - 0.00017 21.2 0.9 0.0003 20.4 0.3 1.8 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KEY64590.1 - 0.048 13.3 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Trp_DMAT PF11991.3 KEY64591.1 - 4.2e-55 187.4 0.0 5.3e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Methyltransf_2 PF00891.13 KEY64592.1 - 1.4e-28 99.7 0.0 2.1e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KEY64592.1 - 0.0029 17.3 0.2 0.01 15.6 0.0 2.1 2 0 0 2 2 2 1 Dimerisation domain p450 PF00067.17 KEY64593.1 - 1.5e-43 149.0 0.0 2e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.14 KEY64594.1 - 2.7e-53 181.0 0.0 3.6e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY64594.1 - 5.7e-26 91.5 0.0 1.5e-25 90.1 0.0 1.7 2 0 0 2 2 1 1 GMC oxidoreductase p450 PF00067.17 KEY64594.1 - 2.1e-09 36.4 0.0 2.8e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_3 PF13738.1 KEY64594.1 - 4.3e-08 33.4 0.1 0.002 18.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEY64594.1 - 3.1e-07 29.5 2.1 5.1e-06 25.5 1.5 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEY64594.1 - 2.7e-06 26.5 0.5 7.2e-06 25.1 0.4 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY64594.1 - 8.9e-05 22.4 0.1 0.00025 21.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KEY64594.1 - 0.00049 19.1 0.1 0.00082 18.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEY64594.1 - 0.0028 17.5 0.2 0.0067 16.3 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEY64594.1 - 0.0083 15.2 0.0 0.13 11.3 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 KEY64594.1 - 0.019 14.7 1.0 0.058 13.1 0.1 2.2 3 0 0 3 3 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KEY64594.1 - 0.051 12.2 0.2 0.074 11.6 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 KEY64594.1 - 0.11 10.9 0.0 0.21 10.0 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein AMP-binding PF00501.23 KEY64595.1 - 0 1388.8 0.0 5.9e-87 291.7 0.0 5.2 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 KEY64595.1 - 4.3e-267 882.8 19.1 1.5e-60 204.5 1.1 5.7 5 0 0 5 5 5 5 Condensation domain HxxPF_rpt PF13745.1 KEY64595.1 - 2.1e-103 338.8 22.4 8.9e-23 80.4 0.4 6.3 5 0 0 5 5 5 5 HxxPF-repeated domain PP-binding PF00550.20 KEY64595.1 - 3.4e-65 216.2 8.0 1.7e-12 47.3 0.0 6.2 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KEY64595.1 - 2.1e-41 140.7 6.5 5.8e-06 27.1 0.0 10.5 10 0 0 10 10 10 8 AMP-binding enzyme C-terminal domain Methyltransf_12 PF08242.7 KEY64595.1 - 8.9e-27 93.4 0.3 2e-06 28.1 0.0 5.8 5 0 0 5 5 5 4 Methyltransferase domain Methyltransf_18 PF12847.2 KEY64595.1 - 1.4e-26 93.2 0.0 1.7e-05 25.3 0.0 5.3 4 0 0 4 4 4 4 Methyltransferase domain Methyltransf_31 PF13847.1 KEY64595.1 - 3.1e-26 91.8 0.0 2.9e-07 30.1 0.0 4.9 4 0 0 4 4 4 4 Methyltransferase domain Methyltransf_23 PF13489.1 KEY64595.1 - 5.4e-26 91.2 0.2 4.6e-06 26.4 0.0 6.2 7 0 0 7 7 6 4 Methyltransferase domain Methyltransf_26 PF13659.1 KEY64595.1 - 5.9e-25 87.5 0.0 2.2e-05 24.4 0.0 5.1 4 0 0 4 4 4 4 Methyltransferase domain Methyltransf_25 PF13649.1 KEY64595.1 - 6.6e-22 77.7 0.0 0.00033 20.9 0.0 5.1 4 0 0 4 4 4 4 Methyltransferase domain Methyltransf_11 PF08241.7 KEY64595.1 - 2e-20 73.0 0.0 2.7e-05 24.5 0.0 5.0 4 0 0 4 4 4 4 Methyltransferase domain Abhydrolase_6 PF12697.2 KEY64595.1 - 4.7e-09 36.4 0.2 1.5e-08 34.7 0.2 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_16 PF10294.4 KEY64595.1 - 6.3e-09 35.5 0.3 0.73 9.2 0.0 4.6 4 0 0 4 4 4 3 Putative methyltransferase MTS PF05175.9 KEY64595.1 - 7.1e-08 32.0 1.6 0.35 10.2 0.0 4.7 4 0 0 4 4 4 2 Methyltransferase small domain Abhydrolase_5 PF12695.2 KEY64595.1 - 4.4e-07 29.7 0.0 1.3e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_9 PF08003.6 KEY64595.1 - 5.7e-07 28.5 0.1 0.0029 16.3 0.0 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF1698) Thioesterase PF00975.15 KEY64595.1 - 7.7e-07 29.5 1.8 4.2e-06 27.1 0.0 3.2 4 0 0 4 4 3 1 Thioesterase domain Methyltransf_24 PF13578.1 KEY64595.1 - 2.3e-05 25.1 0.0 0.28 12.0 0.0 4.8 5 0 0 5 5 3 1 Methyltransferase domain DUF3239 PF11580.3 KEY64595.1 - 0.028 14.4 0.9 7.7 6.5 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3239) DUF1413 PF07205.6 KEY64595.1 - 0.037 13.5 0.3 1.7 8.2 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1413) Viral_P18 PF04521.8 KEY64595.1 - 0.11 11.8 0.1 19 4.6 0.0 4.1 5 0 0 5 5 5 0 ssRNA positive strand viral 18kD cysteine rich protein Armet PF10208.4 KEY64595.1 - 3.9 7.1 0.0 5e+02 0.2 0.0 3.7 5 0 0 5 5 5 0 Degradation arginine-rich protein for mis-folding Spore_YtrH PF14034.1 KEY64595.1 - 5.3 7.0 3.2 38 4.2 0.0 3.7 4 0 0 4 4 3 0 Sporulation protein YtrH Rad51 PF08423.6 KEY64596.1 - 5e-24 84.5 0.0 7.1e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KEY64596.1 - 6e-14 51.9 0.1 1e-13 51.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 KEY64596.1 - 7.9e-05 21.8 0.1 0.00069 18.7 0.1 1.9 1 1 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KEY64596.1 - 0.0015 17.6 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 KaiC NACHT PF05729.7 KEY64596.1 - 0.16 11.6 0.1 0.73 9.4 0.1 1.9 1 1 0 1 1 1 0 NACHT domain Pept_tRNA_hydro PF01195.14 KEY64596.1 - 0.21 11.0 0.0 3.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Peptidyl-tRNA hydrolase RNA_pol_Rpb2_6 PF00562.23 KEY64597.1 - 2.9e-117 391.6 0.1 1.2e-116 389.6 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KEY64597.1 - 1.2e-41 141.9 0.2 1.2e-41 141.9 0.1 1.5 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 KEY64597.1 - 5.5e-30 103.4 0.2 1.6e-29 102.0 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 KEY64597.1 - 2.8e-28 98.6 0.1 6.1e-28 97.5 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 KEY64597.1 - 7.9e-21 73.5 0.0 1.6e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 KEY64597.1 - 3.5e-20 71.5 0.1 8.8e-20 70.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 KEY64597.1 - 5e-12 45.6 1.4 1.4e-11 44.1 1.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Carn_acyltransf PF00755.15 KEY64598.1 - 4.9e-170 566.4 0.0 8.9e-154 512.8 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase RRN7 PF11781.3 KEY64599.1 - 1.1 8.7 16.4 11 5.5 2.9 4.2 3 1 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 MFS_1 PF07690.11 KEY64600.1 - 2.7e-19 69.1 58.4 3.3e-18 65.5 9.1 3.1 1 1 1 3 3 3 3 Major Facilitator Superfamily HSP70 PF00012.15 KEY64602.1 - 8.4e-263 872.7 4.5 9.5e-263 872.5 3.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KEY64602.1 - 5.8e-17 61.2 0.0 9.6e-16 57.2 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Actin PF00022.14 KEY64602.1 - 0.01 14.2 0.0 0.19 10.1 0.0 2.3 1 1 0 1 1 1 0 Actin FGGY_C PF02782.11 KEY64602.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 KEY64602.1 - 0.013 14.6 0.0 0.039 13.0 0.0 1.8 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase FtsA PF14450.1 KEY64602.1 - 0.022 14.5 2.8 1.5 8.7 1.9 3.3 1 1 0 1 1 1 0 Cell division protein FtsA StbA PF06406.6 KEY64602.1 - 0.039 12.8 0.0 0.079 11.8 0.0 1.5 1 0 0 1 1 1 0 StbA protein PMBR PF09373.5 KEY64602.1 - 0.98 9.4 3.9 1.1 9.3 0.0 2.7 3 0 0 3 3 3 0 Pseudomurein-binding repeat GMC_oxred_N PF00732.14 KEY64603.1 - 0.0001 21.5 0.0 0.00019 20.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Polysacc_synt_C PF14667.1 KEY64604.1 - 0.15 11.8 6.4 0.17 11.7 1.1 2.1 1 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain EVE PF01878.13 KEY64605.1 - 4.7e-49 166.0 0.0 7.6e-49 165.4 0.0 1.3 1 0 0 1 1 1 1 EVE domain RNA_pol_Rbc25 PF08292.7 KEY64605.1 - 0.089 12.9 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Trypan_PARP PF05887.6 KEY64605.1 - 0.35 10.6 7.2 0.59 9.9 5.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) IDO PF01231.13 KEY64607.1 - 2e-141 471.2 0.0 2.5e-141 470.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 KEY64607.1 - 0.035 12.6 0.0 0.29 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) Aminotran_5 PF00266.14 KEY64608.1 - 2.4e-07 29.8 0.0 6.7e-06 25.0 0.0 2.2 2 1 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KEY64608.1 - 0.014 14.4 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Kinesin PF00225.18 KEY64610.1 - 2.2e-114 381.6 0.1 4e-114 380.7 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Fungal_trans PF04082.13 KEY64610.1 - 2.6e-13 49.4 0.1 4.9e-12 45.2 0.0 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY64610.1 - 1e-06 28.5 14.0 2e-06 27.5 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Serglycin PF04360.7 KEY64610.1 - 0.048 13.3 1.4 0.14 11.8 1.0 1.8 1 0 0 1 1 1 0 Serglycin zf-C2H2 PF00096.21 KEY64612.1 - 3.4e-06 27.0 3.3 0.019 15.2 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY64612.1 - 0.00019 21.4 1.9 0.046 14.0 0.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KEY64612.1 - 0.018 15.1 3.7 2.4 8.4 0.1 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KEY64612.1 - 0.13 12.4 1.1 3.1 7.9 0.6 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 KEY64612.1 - 0.14 12.1 3.0 3.6 7.6 0.0 2.4 1 1 1 2 2 2 0 C2H2-type zinc finger FTA2 PF13095.1 KEY64613.1 - 2.2e-16 60.0 0.0 3.8e-09 36.4 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 adh_short PF00106.20 KEY64615.1 - 1.8e-26 93.0 1.3 2.6e-26 92.5 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY64615.1 - 2.3e-23 83.2 0.0 3.2e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY64615.1 - 2e-11 43.8 0.3 3.2e-11 43.2 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY64615.1 - 0.00065 19.2 0.2 0.0026 17.2 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY64615.1 - 0.11 12.4 0.4 0.43 10.5 0.3 2.0 1 1 0 1 1 1 0 NADH(P)-binding Abhydrolase_5 PF12695.2 KEY64616.1 - 5.9e-15 55.2 0.1 8.8e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 KEY64616.1 - 1.6e-07 30.0 0.1 0.00091 17.6 0.0 2.3 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.2 KEY64616.1 - 2.6e-05 24.2 0.6 7.2e-05 22.7 0.1 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KEY64616.1 - 0.00089 18.2 0.0 0.0016 17.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 KEY64616.1 - 0.022 13.9 0.0 0.056 12.6 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Lipase_3 PF01764.20 KEY64616.1 - 0.056 13.0 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2305 PF10230.4 KEY64616.1 - 0.2 11.0 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF605 PF04652.11 KEY64617.1 - 9.3e-91 305.0 9.9 1e-90 304.8 6.9 1.0 1 0 0 1 1 1 1 Vta1 like DUF2654 PF10849.3 KEY64617.1 - 0.012 15.3 0.0 0.059 13.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2654) DUF812 PF05667.6 KEY64617.1 - 0.071 11.6 0.2 0.095 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) NIF PF03031.13 KEY64619.1 - 5.2e-36 123.7 0.0 7.4e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Pex14_N PF04695.8 KEY64619.1 - 0.43 10.6 7.7 1.7 8.7 5.3 1.9 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EndIII_4Fe-2S PF10576.4 KEY64620.1 - 0.055 13.6 1.4 3.2 8.0 0.1 2.8 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Metallophos PF00149.23 KEY64621.1 - 1.1e-05 24.9 9.5 0.00021 20.7 4.7 3.4 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Tim17 PF02466.14 KEY64623.1 - 0.18 11.8 7.2 0.48 10.4 4.7 1.8 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Alk_phosphatase PF00245.15 KEY64624.1 - 9.4e-71 238.6 0.0 1.6e-70 237.9 0.0 1.3 1 1 0 1 1 1 1 Alkaline phosphatase Pro_dh PF01619.13 KEY64625.1 - 1.1e-40 139.6 0.0 1.4e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Phage_CI_repr PF07022.8 KEY64625.1 - 0.14 12.2 0.1 0.78 9.8 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain CGI-121 PF08617.5 KEY64626.1 - 1.8e-48 164.2 0.0 2.1e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Stork_head PF10264.4 KEY64626.1 - 0.045 13.9 0.0 0.09 12.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain Zn_clus PF00172.13 KEY64627.1 - 1.5e-05 24.7 17.5 1.5e-05 24.7 12.1 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Carb_anhydrase PF00194.16 KEY64628.1 - 3.6e-21 75.2 0.0 1.2e-20 73.5 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Adenylsucc_synt PF00709.16 KEY64629.1 - 1.2e-05 24.1 0.0 1.2e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase HATPase_c PF02518.21 KEY64631.1 - 1e-19 70.2 0.0 2.2e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KEY64631.1 - 3.1e-16 59.3 0.0 1.7e-15 56.9 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KEY64631.1 - 1.7e-13 50.3 0.3 5.9e-13 48.6 0.2 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 KEY64631.1 - 0.0042 17.1 0.0 0.036 14.1 0.0 2.5 2 1 0 2 2 2 1 GAF domain HATPase_c_2 PF13581.1 KEY64631.1 - 0.0063 16.2 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain GAF_2 PF13185.1 KEY64631.1 - 0.058 13.8 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 GAF domain Methyltransf_PK PF05891.7 KEY64632.1 - 8.2e-76 254.1 0.0 9.9e-76 253.8 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 KEY64632.1 - 0.00022 20.9 0.0 0.00036 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY64632.1 - 0.00081 19.8 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY64632.1 - 0.038 14.5 0.0 0.073 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KEY64632.1 - 0.053 14.0 0.0 0.09 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KEY64632.1 - 0.14 12.5 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 KEY64632.1 - 0.15 11.0 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase SET PF00856.23 KEY64633.1 - 8.8e-14 52.1 0.0 1.2e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 SET domain GHL15 PF14885.1 KEY64633.1 - 0.0091 16.1 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase family 15 DUF1560 PF07597.6 KEY64634.1 - 0.1 12.6 0.1 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1560) Thioredoxin PF00085.15 KEY64636.1 - 2.9e-32 110.4 0.2 8.9e-25 86.3 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 KEY64636.1 - 2.3e-10 40.5 0.0 4.6e-09 36.3 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KEY64636.1 - 7.9e-10 38.9 0.4 0.0024 18.0 0.0 3.1 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KEY64636.1 - 1.1e-06 28.6 0.0 0.0083 16.2 0.0 4.0 3 2 1 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KEY64636.1 - 0.0018 18.2 0.0 0.0045 16.9 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like HyaE PF07449.6 KEY64636.1 - 0.0019 18.0 0.0 0.42 10.5 0.0 3.4 3 1 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 KEY64636.1 - 0.0049 16.6 2.7 0.44 10.3 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin domain TraF PF13728.1 KEY64636.1 - 0.019 14.4 9.3 3.1 7.2 0.0 3.5 2 1 1 3 3 3 0 F plasmid transfer operon protein AhpC-TSA PF00578.16 KEY64636.1 - 0.031 13.9 0.0 0.078 12.6 0.0 1.6 1 0 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.19 KEY64636.1 - 0.14 12.1 0.3 23 5.0 0.0 2.8 2 0 0 2 2 2 0 Glutaredoxin DUF2360 PF10152.4 KEY64636.1 - 0.24 11.6 9.6 1.3 9.2 1.2 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Pex14_N PF04695.8 KEY64636.1 - 3.6 7.6 12.9 0.071 13.1 1.5 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RNase_PH PF01138.16 KEY64637.1 - 4.1e-35 120.9 0.4 6.7e-35 120.2 0.3 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Phostensin_N PF13916.1 KEY64637.1 - 0.084 12.8 0.2 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal RNase_PH_C PF03725.10 KEY64637.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 ADH_N PF08240.7 KEY64638.1 - 5.9e-28 96.8 2.2 7.1e-28 96.5 0.4 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY64638.1 - 4e-18 65.2 0.5 5.9e-18 64.6 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY64638.1 - 2.9e-05 24.9 0.0 5.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_trans_4_2 PF13477.1 KEY64638.1 - 0.16 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like FAD_binding_4 PF01565.18 KEY64639.1 - 3e-22 78.6 0.3 5.5e-22 77.7 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_11 PF00457.12 KEY64639.1 - 0.026 13.8 0.2 0.052 12.8 0.2 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 11 Peptidase_M3 PF01432.15 KEY64640.1 - 3.4e-100 336.2 0.0 4.2e-100 335.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 DUF221 PF02714.10 KEY64641.1 - 9.2e-95 317.2 12.8 1.9e-94 316.1 8.9 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KEY64641.1 - 6e-43 146.1 0.3 2.2e-42 144.3 0.2 2.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KEY64641.1 - 8.6e-20 70.4 0.0 4.1e-19 68.2 0.0 2.2 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 KEY64641.1 - 6.1e-12 45.8 0.0 1.7e-11 44.4 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 KEY64641.1 - 0.096 12.6 0.0 0.38 10.7 0.0 2.1 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) APH PF01636.18 KEY64642.1 - 4e-30 105.3 0.4 7e-30 104.5 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KEY64642.1 - 0.0023 16.9 0.0 0.0065 15.4 0.0 1.7 2 0 0 2 2 2 1 Fructosamine kinase DUF1679 PF07914.6 KEY64642.1 - 0.0028 16.3 0.0 0.14 10.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.15 KEY64642.1 - 0.0073 15.4 0.0 0.017 14.2 0.0 1.5 2 0 0 2 2 2 1 Ecdysteroid kinase Pkinase PF00069.20 KEY64642.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain adh_short PF00106.20 KEY64643.1 - 3.1e-12 46.7 0.4 5.8e-12 45.8 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY64643.1 - 0.0002 21.2 0.0 0.0003 20.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEY64643.1 - 0.00056 19.4 0.0 0.0012 18.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY64643.1 - 0.0049 16.8 0.1 0.01 15.8 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KEY64643.1 - 0.011 15.4 0.1 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 KR domain Eno-Rase_NADH_b PF12242.3 KEY64643.1 - 0.037 13.7 0.1 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Stig1 PF04885.8 KEY64644.1 - 6.3e-37 126.8 172.0 1.9e-07 31.3 14.8 7.1 1 1 6 7 7 7 7 Stigma-specific protein, Stig1 HET PF06985.6 KEY64645.1 - 4.6e-22 78.6 10.3 3e-19 69.5 1.5 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) PAS_11 PF14598.1 KEY64645.1 - 0.012 15.5 0.1 0.044 13.7 0.1 1.9 2 0 0 2 2 2 0 PAS domain Cu_amine_oxid PF01179.15 KEY64646.1 - 1.2e-107 360.1 5.1 1.6e-107 359.8 3.5 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 KEY64646.1 - 6e-23 80.5 1.0 1.6e-22 79.1 0.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 KEY64646.1 - 9.7e-05 22.3 0.0 0.00022 21.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain SNF2_N PF00176.18 KEY64647.1 - 2.2e-11 43.0 0.0 7.4e-07 28.2 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain OPT PF03169.10 KEY64648.1 - 3e-88 296.8 42.4 4e-88 296.4 29.4 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.1 KEY64648.1 - 0.27 10.3 1.1 0.98 8.4 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) DUF1929 PF09118.6 KEY64649.1 - 5.8e-24 84.0 0.1 1.2e-23 83.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_1 PF01344.20 KEY64649.1 - 7.5e-13 47.8 0.0 0.00086 18.7 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 KEY64649.1 - 2.6e-12 46.3 2.2 0.0031 17.6 0.0 5.0 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.1 KEY64649.1 - 2.3e-09 36.8 7.3 0.0028 17.3 0.1 5.4 4 3 0 4 4 4 3 Galactose oxidase, central domain PAN_1 PF00024.21 KEY64649.1 - 1.6e-07 30.9 0.1 3.2e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 PAN domain Kelch_3 PF13415.1 KEY64649.1 - 3.3e-06 27.1 2.2 0.0046 17.0 0.0 4.0 4 0 0 4 4 4 1 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.6 KEY64649.1 - 6.2e-06 25.4 0.0 0.04 12.9 0.0 2.9 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_2 PF07646.10 KEY64649.1 - 1.3e-05 24.7 0.0 0.99 9.2 0.0 5.0 4 2 0 4 4 4 1 Kelch motif PAN_4 PF14295.1 KEY64649.1 - 0.0065 16.1 2.8 0.011 15.3 1.0 2.1 2 0 0 2 2 2 1 PAN domain adh_short PF00106.20 KEY64650.1 - 8.2e-17 61.6 0.1 8.2e-17 61.6 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY64650.1 - 1.3e-06 28.2 0.2 1.3e-06 28.2 0.1 1.8 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KEY64650.1 - 6.1e-06 26.1 0.0 9.5e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEY64650.1 - 0.0001 21.8 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY64650.1 - 0.019 14.9 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding O-FucT PF10250.4 KEY64650.1 - 0.24 10.4 0.1 2.7 6.9 0.0 2.1 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Herpes_gE PF02480.11 KEY64651.1 - 0.059 11.6 0.0 0.063 11.5 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Consortin_C PF15281.1 KEY64651.1 - 0.13 11.8 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Consortin C-terminus MFS_1 PF07690.11 KEY64652.1 - 2.2e-14 52.9 15.5 2.2e-14 52.9 10.7 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY64652.1 - 3.1e-11 42.5 0.8 3.1e-11 42.5 0.6 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter Cu-oxidase_3 PF07732.10 KEY64653.1 - 1.3e-41 140.9 6.7 4.7e-41 139.2 0.6 3.4 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KEY64653.1 - 3.9e-39 133.3 1.1 3.9e-39 133.3 0.8 3.3 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 KEY64653.1 - 2.2e-37 128.3 0.1 8.6e-35 119.9 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase SNF2_N PF00176.18 KEY64654.1 - 4.3e-16 58.5 0.0 6.9e-10 38.1 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain DEAD PF00270.24 KEY64654.1 - 0.013 14.9 0.0 1.2 8.6 0.0 3.5 4 0 0 4 4 4 0 DEAD/DEAH box helicase Arginase PF00491.16 KEY64655.1 - 2.1e-92 309.3 0.0 2.5e-92 309.1 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KEY64655.1 - 0.0048 17.1 0.1 0.0048 17.1 0.1 1.6 2 0 0 2 2 2 1 UPF0489 domain Fungal_trans PF04082.13 KEY64656.1 - 2.6e-22 78.9 0.0 4.4e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY64656.1 - 1.3e-05 25.0 9.3 2.2e-05 24.2 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.16 KEY64657.1 - 1.9e-100 336.5 41.0 2.3e-100 336.2 28.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEY64657.1 - 7.2e-34 117.0 44.1 1.3e-33 116.2 30.5 1.4 1 1 0 1 1 1 1 Amino acid permease AAA PF00004.24 KEY64659.1 - 2.8e-16 59.9 0.0 7.7e-16 58.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEY64659.1 - 9.1e-05 23.2 0.4 0.00056 20.7 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KEY64659.1 - 0.00027 20.9 0.0 0.0057 16.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 KEY64659.1 - 0.001 18.7 0.0 0.0036 17.0 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KEY64659.1 - 0.002 18.2 1.0 0.066 13.3 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 KEY64659.1 - 0.0035 17.0 0.0 0.14 11.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) KaiC PF06745.8 KEY64659.1 - 0.0036 16.4 0.4 0.009 15.1 0.3 1.7 1 0 0 1 1 1 1 KaiC AAA_33 PF13671.1 KEY64659.1 - 0.0041 17.0 0.6 0.014 15.2 0.0 2.2 3 0 0 3 3 3 1 AAA domain Torsin PF06309.6 KEY64659.1 - 0.012 15.4 0.0 0.034 14.0 0.0 1.7 1 0 0 1 1 1 0 Torsin AAA_28 PF13521.1 KEY64659.1 - 0.024 14.6 0.4 0.081 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KEY64659.1 - 0.03 13.3 0.0 0.06 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 KEY64659.1 - 0.046 14.0 0.3 0.23 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KEY64659.1 - 0.053 13.1 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KEY64659.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Clr5 PF14420.1 KEY64660.1 - 2.9e-17 62.2 0.5 5.5e-17 61.4 0.4 1.5 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 KEY64660.1 - 0.064 13.1 0.0 2.1 8.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M28 PF04389.12 KEY64661.1 - 5.6e-34 117.4 0.1 8.7e-34 116.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KEY64661.1 - 4.3e-05 23.1 0.0 7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 ADH_zinc_N_2 PF13602.1 KEY64662.1 - 2e-21 77.2 0.0 1.5e-20 74.3 0.0 2.5 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KEY64662.1 - 7.9e-17 61.0 0.1 3.5e-16 58.9 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.20 KEY64662.1 - 5.2e-12 45.9 0.9 2.3e-11 43.9 0.0 2.4 3 0 0 3 3 3 1 short chain dehydrogenase ADH_N PF08240.7 KEY64662.1 - 3e-09 36.5 0.2 1.8e-08 34.1 0.0 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 KEY64662.1 - 3.5e-06 26.6 0.0 1.1e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KEY64662.1 - 0.00018 20.5 0.0 0.0003 19.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KEY64662.1 - 0.00068 19.3 0.2 0.0018 17.9 0.0 1.8 2 0 0 2 2 2 1 KR domain Abhydrolase_6 PF12697.2 KEY64663.1 - 6.7e-26 91.5 0.0 8.3e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY64663.1 - 1.6e-15 57.3 0.1 3.9e-14 52.7 0.1 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY64663.1 - 1.2e-09 38.0 0.0 2e-09 37.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KEY64663.1 - 1.4e-08 33.5 0.0 1.8e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 KEY64663.1 - 3.2e-08 33.2 0.0 5.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase BAAT_C PF08840.6 KEY64663.1 - 0.0083 15.8 0.0 0.084 12.5 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.2 KEY64664.1 - 0.00011 22.2 0.2 0.00024 21.0 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KEY64664.1 - 0.00066 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KEY64664.1 - 0.00091 18.9 0.0 0.0026 17.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 KEY64664.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) adh_short PF00106.20 KEY64665.1 - 1.4e-22 80.3 1.4 2e-22 79.8 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY64665.1 - 3.7e-15 56.3 0.3 4.1e-15 56.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KEY64665.1 - 1.5e-06 27.5 0.0 1.2e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_2 PF03446.10 KEY64665.1 - 2.2e-06 27.6 0.1 4.4e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 KEY64665.1 - 6.3e-06 26.3 0.3 1.1e-05 25.4 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KEY64665.1 - 1.2e-05 24.7 0.3 2.3e-05 23.7 0.1 1.5 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 KEY64665.1 - 7.6e-05 22.4 0.3 0.00011 21.8 0.2 1.2 1 0 0 1 1 1 1 KR domain ApbA PF02558.11 KEY64665.1 - 0.0023 17.3 0.1 0.0037 16.7 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DFP PF04127.10 KEY64665.1 - 0.0041 16.7 0.3 0.008 15.8 0.2 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein F420_oxidored PF03807.12 KEY64665.1 - 0.0073 16.7 0.1 0.016 15.6 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.4 KEY64665.1 - 0.0092 15.7 0.1 0.02 14.6 0.1 1.6 1 0 0 1 1 1 1 Rossmann-like domain 3HCDH_N PF02737.13 KEY64665.1 - 0.033 13.8 0.2 0.054 13.1 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 KEY64665.1 - 0.065 13.2 0.2 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain PAE PF03283.8 KEY64665.1 - 0.076 11.6 0.3 0.1 11.2 0.2 1.2 1 0 0 1 1 1 0 Pectinacetylesterase ADH_zinc_N PF00107.21 KEY64665.1 - 0.11 12.0 0.2 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Peptidase_M14 PF00246.19 KEY64666.1 - 5e-44 150.9 0.0 7.1e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 KEY64666.1 - 0.046 13.4 0.0 0.23 11.1 0.0 2.3 2 1 0 2 2 2 0 Carboxypeptidase activation peptide ketoacyl-synt PF00109.21 KEY64667.1 - 2.4e-70 236.8 0.1 5.9e-70 235.6 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 KEY64667.1 - 2.3e-57 194.4 0.5 5.7e-57 193.1 0.1 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KEY64667.1 - 1.5e-54 185.5 0.1 2.9e-54 184.5 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KEY64667.1 - 2.4e-50 170.7 0.1 7.7e-50 169.0 0.1 2.0 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KEY64667.1 - 5.1e-38 130.6 0.8 1.8e-37 128.8 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KEY64667.1 - 2.2e-37 127.4 0.0 1.7e-36 124.6 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KEY64667.1 - 3.2e-16 59.0 0.3 1.8e-15 56.6 0.2 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY64667.1 - 1.2e-10 42.3 0.0 2.1e-09 38.3 0.0 3.2 4 0 0 4 4 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY64667.1 - 1.5e-07 31.0 0.2 3.5e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KEY64667.1 - 3.1e-05 24.1 0.1 7.9e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KEY64667.1 - 0.0029 16.6 0.7 0.0072 15.3 0.2 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KEY64667.1 - 0.0049 16.4 0.1 0.016 14.8 0.1 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short_C2 PF13561.1 KEY64668.1 - 1.2e-28 100.5 0.6 1.4e-28 100.3 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEY64668.1 - 3.4e-20 72.6 3.8 8e-20 71.4 2.7 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY64668.1 - 8.9e-09 35.2 0.5 8.9e-09 35.2 0.3 1.5 2 0 0 2 2 2 1 KR domain Cupin_2 PF07883.6 KEY64669.1 - 2.3e-07 30.1 0.3 2.3e-06 27.0 0.0 2.4 1 1 1 2 2 2 1 Cupin domain Cupin_3 PF05899.7 KEY64669.1 - 0.03 13.7 0.0 0.73 9.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF861) adh_short PF00106.20 KEY64670.1 - 1.1e-19 70.9 0.1 1.6e-19 70.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY64670.1 - 4.1e-12 46.4 0.0 5e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KEY64670.1 - 0.0021 18.0 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KEY64670.1 - 0.0061 16.2 0.2 0.011 15.4 0.2 1.5 1 1 0 1 1 1 1 KR domain p450 PF00067.17 KEY64672.1 - 4e-50 170.6 0.0 2.6e-45 154.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 KEY64673.1 - 1.3e-70 238.2 0.0 1.5e-70 237.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 KEY64674.1 - 9.2e-17 61.4 0.5 3e-16 59.8 0.0 2.0 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 KEY64674.1 - 1.8e-08 34.2 0.2 3.7e-08 33.2 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KEY64674.1 - 0.00086 19.1 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEY64674.1 - 0.0097 15.3 0.0 0.02 14.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KEY64674.1 - 0.016 14.4 0.1 0.023 13.9 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Trp_DMAT PF11991.3 KEY64675.1 - 4e-83 279.6 0.3 4.7e-83 279.3 0.2 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase FAD_binding_4 PF01565.18 KEY64676.1 - 4.5e-22 78.0 0.6 7.4e-22 77.3 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY64676.1 - 0.0019 18.0 0.4 0.0054 16.6 0.3 1.8 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 KEY64677.1 - 1.7e-14 54.0 0.5 2.6e-14 53.5 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY64677.1 - 9e-11 41.7 0.4 1.3e-10 41.2 0.3 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY64677.1 - 0.00056 19.7 0.0 0.00085 19.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans_2 PF11951.3 KEY64678.1 - 4.3e-05 22.2 1.5 4.3e-05 22.2 1.1 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3961 PF13106.1 KEY64678.1 - 0.6 9.7 2.9 1.4 8.5 2.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) adh_short PF00106.20 KEY64679.1 - 8.9e-16 58.2 0.1 3.3e-15 56.4 0.0 1.9 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 KEY64679.1 - 1.1e-06 28.3 0.3 2.6e-06 27.2 0.0 1.8 3 0 0 3 3 3 1 KR domain Epimerase PF01370.16 KEY64679.1 - 8.5e-06 25.3 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KEY64679.1 - 4.7e-05 23.2 0.0 7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.7 KEY64679.1 - 0.0011 17.9 0.0 0.0023 16.9 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KEY64679.1 - 0.012 15.6 0.0 0.032 14.2 0.0 1.8 1 0 0 1 1 1 0 NADH(P)-binding YjeF_N PF03853.10 KEY64679.1 - 0.017 14.7 0.1 0.039 13.5 0.0 1.5 2 0 0 2 2 2 0 YjeF-related protein N-terminus FAD_binding_3 PF01494.14 KEY64680.1 - 4.7e-21 75.2 1.3 2.2e-20 73.0 0.9 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEY64680.1 - 9.3e-08 31.3 1.6 0.0063 15.4 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEY64680.1 - 7.6e-07 28.3 4.6 0.012 14.5 0.1 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein Amino_oxidase PF01593.19 KEY64680.1 - 5.3e-06 25.7 1.1 0.023 13.7 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 KEY64680.1 - 5e-05 22.1 0.7 0.00038 19.2 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.1 KEY64680.1 - 6e-05 22.9 0.2 6e-05 22.9 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KEY64680.1 - 7.2e-05 23.1 1.2 0.07 13.5 0.1 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEY64680.1 - 0.017 14.9 0.4 0.05 13.4 0.3 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KEY64680.1 - 0.037 13.5 0.0 0.09 12.3 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2204 PF09970.4 KEY64680.1 - 0.23 10.9 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) NAD_binding_9 PF13454.1 KEY64680.1 - 0.24 11.1 2.2 5.8 6.6 0.1 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KEY64680.1 - 0.28 11.1 1.4 0.5 10.4 0.2 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEY64680.1 - 0.46 9.2 4.7 0.063 12.1 0.4 1.6 2 0 0 2 2 2 0 FAD binding domain Fungal_trans PF04082.13 KEY64681.1 - 7.9e-13 47.8 1.6 1.4e-12 47.0 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY64681.1 - 6.7e-08 32.3 15.1 1.3e-07 31.4 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.1 KEY64682.1 - 1.2e-09 38.2 0.0 1.7e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEY64682.1 - 7.4e-09 35.7 0.2 6e-08 32.7 0.2 2.3 2 1 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 KEY64682.1 - 0.037 13.4 0.1 0.11 11.8 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.5 KEY64682.1 - 0.042 13.5 0.1 0.26 10.9 0.0 2.0 2 1 0 2 2 2 0 KR domain FAD_binding_4 PF01565.18 KEY64683.1 - 3.9e-26 91.1 1.4 3.9e-26 91.1 1.0 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KEY64683.1 - 1.3e-05 24.9 0.3 3.7e-05 23.5 0.2 1.8 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 KEY64684.1 - 4.2e-23 82.0 0.0 6e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY64684.1 - 1.3e-14 54.5 0.0 1.7e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY64684.1 - 1.4e-08 34.6 0.0 2.1e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KEY64684.1 - 1.5e-07 31.6 0.0 2.9e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 KEY64684.1 - 8.2e-07 28.4 0.0 1.1e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DSBA PF01323.15 KEY64686.1 - 6.9e-32 110.5 0.0 8.5e-32 110.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Baculo_gp64 PF03273.8 KEY64686.1 - 0.12 10.5 0.0 0.16 10.1 0.0 1.1 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family ACT_7 PF13840.1 KEY64687.1 - 0.051 13.0 0.1 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 ACT domain Sugar_tr PF00083.19 KEY64688.1 - 3.3e-77 259.9 22.4 3.9e-77 259.7 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY64688.1 - 1.2e-14 53.7 67.6 3.4e-12 45.7 26.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.18 KEY64689.1 - 1.1e-20 73.5 3.5 2.1e-20 72.6 2.4 1.5 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.11 KEY64690.1 - 1e-43 149.4 58.8 1.2e-41 142.6 30.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 KEY64691.1 - 3e-17 63.2 0.9 5e-17 62.5 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY64691.1 - 1.3e-07 31.4 0.0 3.1e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY64691.1 - 1.4e-06 28.0 0.0 0.00032 20.3 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF1057 PF06342.7 KEY64691.1 - 0.0012 17.7 0.0 0.002 17.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_2 PF02230.11 KEY64691.1 - 0.087 12.2 0.0 2.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase p450 PF00067.17 KEY64692.1 - 4.8e-26 91.3 0.0 1.3e-19 70.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 SGL PF08450.7 KEY64693.1 - 7.1e-13 48.4 0.1 2.7e-10 40.0 0.0 2.5 3 0 0 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region DUF1929 PF09118.6 KEY64694.1 - 3.5e-24 84.7 0.1 9.4e-24 83.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) F5_F8_type_C PF00754.20 KEY64694.1 - 2.4e-22 79.1 0.9 2.4e-22 79.1 0.6 2.2 2 0 0 2 2 2 1 F5/8 type C domain Kelch_6 PF13964.1 KEY64694.1 - 5.2e-14 51.7 8.5 9.6e-07 28.7 0.0 5.3 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 KEY64694.1 - 1.4e-13 50.3 12.1 1.9e-06 27.5 0.0 5.1 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.20 KEY64694.1 - 2.5e-11 42.9 2.4 0.00043 19.7 0.0 4.1 3 0 0 3 3 3 3 Kelch motif Glyoxal_oxid_N PF07250.6 KEY64694.1 - 5.5e-10 38.7 0.4 3.1e-05 23.1 0.6 2.6 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_2 PF07646.10 KEY64694.1 - 1.3e-07 31.1 0.2 0.017 14.8 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 KEY64694.1 - 7.8e-07 29.0 17.4 0.01 15.9 0.6 6.2 5 1 0 5 5 5 3 Galactose oxidase, central domain Amino_oxidase PF01593.19 KEY64695.1 - 3.1e-37 128.7 0.0 9.4e-37 127.1 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KEY64695.1 - 1.9e-12 47.0 0.0 4.4e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KEY64695.1 - 1.5e-05 25.3 0.8 7.7e-05 23.0 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY64695.1 - 1.8e-05 24.9 0.1 0.0059 16.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEY64695.1 - 3.1e-05 23.0 0.0 0.00013 21.0 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KEY64695.1 - 0.00038 20.2 0.4 1 9.0 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding Thi4 PF01946.12 KEY64695.1 - 0.00039 19.5 0.1 0.0016 17.5 0.1 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KEY64695.1 - 0.00047 18.7 0.3 0.0018 16.8 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 KEY64695.1 - 0.0038 16.3 1.0 0.0077 15.3 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 KEY64695.1 - 0.0063 16.1 0.4 0.046 13.3 0.2 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KEY64695.1 - 0.01 14.7 0.5 0.016 14.0 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 KEY64695.1 - 0.015 15.1 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEY64695.1 - 0.042 12.0 0.3 0.06 11.5 0.2 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like AlaDh_PNT_C PF01262.16 KEY64695.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ank_2 PF12796.2 KEY64696.1 - 6.6e-13 48.8 0.0 1.3e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEY64696.1 - 6.6e-12 45.6 0.4 1.9e-07 31.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KEY64696.1 - 1.9e-10 40.0 1.8 5.2e-06 25.9 0.2 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KEY64696.1 - 1.5e-08 34.6 1.4 7.7e-07 29.1 0.3 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY64696.1 - 6.9e-08 32.0 0.3 0.0092 16.1 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat APH PF01636.18 KEY64697.1 - 6.7e-14 52.1 0.0 2.6e-13 50.2 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEY64697.1 - 9.9e-05 21.9 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 KEY64697.1 - 0.25 9.9 0.0 0.39 9.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 KEY64697.1 - 0.25 10.4 0.0 0.38 9.8 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Amidase PF01425.16 KEY64699.1 - 4.6e-35 121.3 3.0 1.7e-34 119.4 2.6 1.4 2 0 0 2 2 2 1 Amidase PHO4 PF01384.15 KEY64700.1 - 1.2e-97 326.4 19.4 1.5e-97 326.1 13.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF1524 PF07510.6 KEY64701.1 - 3.8e-09 36.5 0.1 4.9e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) Glyco_transf_34 PF05637.7 KEY64702.1 - 3.7e-16 59.3 0.2 8.7e-16 58.1 0.1 1.6 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF605 PF04652.11 KEY64702.1 - 0.027 13.8 28.4 0.035 13.5 19.7 1.2 1 0 0 1 1 1 0 Vta1 like Lipase_GDSL PF00657.17 KEY64703.1 - 9.1e-13 48.5 0.0 1.1e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Amidase PF01425.16 KEY64704.1 - 6.5e-68 229.5 0.0 5.9e-67 226.4 0.0 1.9 1 1 0 1 1 1 1 Amidase zf-C2H2 PF00096.21 KEY64705.1 - 5.3e-05 23.3 0.4 5.3e-05 23.3 0.3 4.6 4 1 0 4 4 4 1 Zinc finger, C2H2 type zf-TRAF PF02176.13 KEY64705.1 - 0.0085 16.4 1.7 0.0085 16.4 1.2 2.9 2 1 0 2 2 2 1 TRAF-type zinc finger zf-C2H2_4 PF13894.1 KEY64705.1 - 0.0091 16.2 0.3 0.0091 16.2 0.2 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEY64705.1 - 0.012 15.8 0.4 0.012 15.8 0.2 4.3 4 1 1 5 5 5 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 KEY64706.1 - 0.3 11.5 5.5 0.79 10.2 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger PsbQ PF05757.6 KEY64708.1 - 0.025 14.0 1.7 0.025 14.0 1.2 2.0 1 1 1 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) DUF4140 PF13600.1 KEY64708.1 - 0.1 13.0 0.9 0.21 12.0 0.1 1.8 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3138 PF11336.3 KEY64708.1 - 0.61 8.1 5.4 1 7.4 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SlyX PF04102.7 KEY64708.1 - 0.99 9.8 5.6 1.2 9.5 2.9 1.9 1 1 0 1 1 1 0 SlyX NUDE_C PF04880.8 KEY64708.1 - 5.3 7.3 6.4 1.7 9.0 2.3 1.8 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region IncA PF04156.9 KEY64709.1 - 0.29 10.7 1.9 0.44 10.1 1.3 1.2 1 0 0 1 1 1 0 IncA protein Ribosomal_S27e PF01667.12 KEY64709.1 - 9 5.9 9.8 1.1 8.8 3.3 2.1 2 0 0 2 2 2 0 Ribosomal protein S27 WSC PF01822.14 KEY64710.1 - 2.1e-26 91.6 13.8 2.4e-16 59.4 8.8 3.0 2 1 0 2 2 2 2 WSC domain C_tripleX PF02363.14 KEY64711.1 - 3.4 7.9 6.4 37 4.6 0.8 4.0 2 0 0 2 2 2 0 Cysteine rich repeat Glyco_hydro_11 PF00457.12 KEY64712.1 - 2.5e-36 124.7 10.7 6.5e-36 123.3 7.4 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 11 Glyco_tranf_2_3 PF13641.1 KEY64714.1 - 8.9e-20 71.4 0.0 1.2e-19 71.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KEY64714.1 - 2.8e-07 29.9 0.0 7.1e-07 28.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KEY64714.1 - 3.1e-06 26.9 0.0 7.7e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF4603 PF15376.1 KEY64715.1 - 0.99 6.5 13.3 1.3 6.1 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Clr5 PF14420.1 KEY64716.1 - 1.2e-19 69.8 3.2 5.2e-19 67.8 0.9 2.8 3 0 0 3 3 3 1 Clr5 domain FAD-oxidase_C PF02913.14 KEY64717.1 - 4.8e-59 199.6 0.1 8.2e-59 198.9 0.1 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KEY64717.1 - 3.7e-36 123.6 0.0 7.4e-36 122.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain UPF0183 PF03676.9 KEY64718.1 - 1.1e-41 142.7 0.0 1.1e-24 86.8 0.0 4.6 4 1 0 4 4 4 4 Uncharacterised protein family (UPF0183) Kinesin PF00225.18 KEY64719.1 - 4.8e-111 370.6 2.9 4.8e-111 370.6 2.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain MFS_1 PF07690.11 KEY64719.1 - 3.7e-45 154.1 56.2 3.7e-45 154.1 39.0 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KEY64719.1 - 1.1e-26 93.2 11.9 1.8e-26 92.5 8.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KEY64719.1 - 1.1e-13 50.5 12.7 1.1e-13 50.5 8.8 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter Microtub_bind PF13931.1 KEY64719.1 - 1.2e-07 31.9 0.8 1.2e-07 31.9 0.6 4.6 2 1 3 5 5 5 1 Kinesin-associated microtubule-binding Apolipoprotein PF01442.13 KEY64719.1 - 0.4 10.1 48.7 0.54 9.7 15.6 3.9 1 1 2 3 3 3 0 Apolipoprotein A1/A4/E domain RRN9 PF10680.4 KEY64720.1 - 2.4e-13 49.6 1.3 2.4e-13 49.6 0.9 2.3 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor Pescadillo_N PF06732.6 KEY64721.1 - 1.6e-113 378.6 0.1 1.6e-113 378.6 0.1 1.7 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 KEY64721.1 - 1.8e-08 34.4 0.0 4.7e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Astro_capsid PF03115.9 KEY64721.1 - 0.039 12.2 5.1 0.063 11.5 3.6 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor PIG-U PF06728.8 KEY64722.1 - 8.8e-124 413.2 23.8 1e-123 413.0 16.5 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Tom37_C PF11801.3 KEY64723.1 - 4.4e-21 75.4 0.0 7.2e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 KEY64723.1 - 6e-20 71.2 0.7 1.5e-19 69.9 0.1 1.9 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 KEY64723.1 - 0.022 14.6 0.0 0.065 13.1 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEY64723.1 - 0.06 13.8 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ATG16 PF08614.6 KEY64724.1 - 0.034 13.9 7.9 0.039 13.7 5.4 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Fmp27_WPPW PF10359.4 KEY64724.1 - 0.075 11.4 7.9 0.093 11.1 5.5 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Metal_resist PF13801.1 KEY64724.1 - 0.094 12.7 5.7 0.15 12.0 3.9 1.5 1 1 0 1 1 1 0 Heavy-metal resistance Jnk-SapK_ap_N PF09744.4 KEY64724.1 - 0.1 12.5 11.0 0.14 12.1 7.6 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Hep_59 PF07052.6 KEY64724.1 - 0.12 12.7 4.8 0.14 12.5 3.3 1.2 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 DUF4226 PF10774.4 KEY64724.1 - 0.2 11.7 3.2 0.28 11.2 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) COG2 PF06148.6 KEY64724.1 - 0.23 11.3 3.5 0.32 10.8 2.4 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 HR1 PF02185.11 KEY64724.1 - 1.1 9.1 9.0 9.9 5.9 1.2 2.3 1 1 1 2 2 2 0 Hr1 repeat V-SNARE PF05008.10 KEY64724.1 - 1.4 9.1 7.7 4.9 7.3 4.3 2.1 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus zf-C4H2 PF10146.4 KEY64724.1 - 1.7 8.5 9.3 2.1 8.3 6.4 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein IncA PF04156.9 KEY64724.1 - 2.6 7.5 6.6 2.7 7.5 4.6 1.1 1 0 0 1 1 1 0 IncA protein ATP-synt_B PF00430.13 KEY64724.1 - 3.4 7.4 8.9 5.1 6.9 6.2 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) zf-C2H2_4 PF13894.1 KEY64726.1 - 3.8e-06 26.8 12.7 0.00063 19.8 1.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEY64726.1 - 6.1e-06 26.2 4.0 6.1e-06 26.2 2.8 3.0 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 KEY64726.1 - 1.7e-05 24.8 11.7 0.0072 16.6 1.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KEY64726.1 - 2.7 8.0 5.8 0.34 10.8 0.6 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2434 PF10361.4 KEY64728.1 - 2.6e-103 345.1 8.9 3.5e-103 344.7 6.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) COG5 PF10392.4 KEY64729.1 - 1.9e-37 128.1 0.8 9.8e-37 125.8 0.2 2.2 2 0 0 2 2 2 1 Golgi transport complex subunit 5 DHFR_2 PF06442.6 KEY64729.1 - 0.071 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 R67 dihydrofolate reductase SPX PF03105.14 KEY64729.1 - 0.16 11.6 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 SPX domain Gelsolin PF00626.17 KEY64730.1 - 1.4e-35 120.8 0.0 1.5e-13 50.1 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat Exo_endo_phos PF03372.18 KEY64731.1 - 9.7e-12 45.3 1.9 1.2e-11 45.0 1.3 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KEY64731.1 - 0.014 14.9 0.1 0.082 12.5 0.1 2.0 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase GFA PF04828.9 KEY64732.1 - 1.1e-13 50.9 0.1 3.5e-13 49.3 0.1 1.9 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme EI24 PF07264.6 KEY64733.1 - 0.062 12.7 20.0 0.43 9.9 13.8 2.0 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DDE_Tnp_1_7 PF13843.1 KEY64734.1 - 6.6e-40 137.2 0.0 8.1e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 Abhydrolase_4 PF08386.5 KEY64736.1 - 2.9e-21 75.3 0.0 5.8e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KEY64736.1 - 1.1e-14 54.5 0.4 1.9e-09 37.4 0.1 3.1 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEY64736.1 - 1.1e-10 41.8 5.6 5.3e-10 39.5 2.2 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY64736.1 - 0.0013 18.5 0.0 0.041 13.6 0.0 2.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3638 PF12340.3 KEY64737.1 - 2.8e-103 343.8 0.6 5.1e-103 342.9 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 KEY64737.1 - 8.7e-16 56.7 0.0 2.1e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Sel1 PF08238.7 KEY64738.1 - 1.2e-16 60.7 22.6 1e-06 29.1 0.1 7.5 7 0 0 7 7 7 3 Sel1 repeat TPR_11 PF13414.1 KEY64738.1 - 0.0065 16.1 0.7 0.4 10.3 0.0 2.7 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KEY64738.1 - 0.0068 15.9 0.2 0.032 13.8 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEY64738.1 - 1.7 8.6 6.7 0.11 12.2 0.2 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SAC3_GANP PF03399.11 KEY64739.1 - 1.8e-25 89.7 0.0 2.5e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KEY64739.1 - 5e-21 74.9 0.0 7.3e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Coatomer_WDAD PF04053.9 KEY64740.1 - 1.6e-150 501.8 0.0 3e-150 500.8 0.0 1.5 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 KEY64740.1 - 1.3e-85 287.5 0.0 1.8e-85 287.0 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 KEY64740.1 - 4.7e-51 168.9 9.8 2.4e-09 36.7 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KEY64740.1 - 0.043 11.9 7.3 0.56 8.2 0.0 3.7 2 1 2 4 4 4 0 Nucleoporin Nup120/160 UDP-g_GGTase PF06427.6 KEY64741.1 - 5e-64 215.4 0.0 1.6e-62 210.5 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KEY64741.1 - 5.3e-05 22.6 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 PAS_9 PF13426.1 KEY64742.1 - 9.4e-36 122.3 4.0 3.5e-19 69.0 0.0 4.6 4 0 0 4 4 4 3 PAS domain PAS_3 PF08447.6 KEY64742.1 - 4.2e-21 74.8 0.0 1.5e-11 44.2 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS PF00989.19 KEY64742.1 - 9e-19 67.3 13.7 1.3e-07 31.3 0.0 5.9 6 1 0 6 6 6 3 PAS fold GATA PF00320.22 KEY64742.1 - 7.1e-15 54.0 8.5 1.6e-14 52.8 5.9 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.5 KEY64742.1 - 1.2e-11 44.6 0.0 2.3e-05 24.3 0.0 3.6 3 0 0 3 3 3 2 PAS fold DUF445 PF04286.7 KEY64742.1 - 0.016 14.7 6.7 0.041 13.4 4.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF445) PAS_8 PF13188.1 KEY64742.1 - 0.094 12.6 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 PAS domain Herpes_UL6 PF01763.11 KEY64742.1 - 0.3 9.2 18.6 0.54 8.3 12.9 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like LMBR1 PF04791.11 KEY64742.1 - 8.7 4.8 7.2 17 3.8 5.0 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein HEAT PF02985.17 KEY64744.1 - 2.2e-23 80.1 17.8 0.00086 19.1 0.0 12.1 12 0 0 12 12 11 5 HEAT repeat HEAT_2 PF13646.1 KEY64744.1 - 1.9e-21 76.1 17.9 1.6e-09 37.8 0.0 8.1 4 3 5 9 9 8 8 HEAT repeats HEAT_EZ PF13513.1 KEY64744.1 - 2.5e-21 75.5 17.0 1.7e-08 34.7 0.1 10.1 7 2 3 10 10 10 5 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KEY64744.1 - 1.5e-11 44.5 3.2 0.023 15.0 0.0 8.0 5 2 4 9 9 9 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 KEY64744.1 - 3.9e-09 35.7 0.0 2.7e-06 26.3 0.1 4.0 4 1 1 5 5 5 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 KEY64744.1 - 2.6e-08 33.4 1.0 0.0035 16.7 0.2 5.5 5 1 1 6 6 6 2 CLASP N terminal RIX1 PF08167.7 KEY64744.1 - 4.5e-08 32.9 0.1 0.001 18.8 0.1 5.3 4 2 2 6 6 6 1 rRNA processing/ribosome biogenesis Adaptin_N PF01602.15 KEY64744.1 - 2.7e-05 22.7 2.1 0.0076 14.6 0.3 3.9 3 1 1 4 4 4 1 Adaptin N terminal region Cnd1 PF12717.2 KEY64744.1 - 0.00021 21.1 2.0 4 7.2 0.0 4.9 3 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 KEY64744.1 - 0.0022 17.8 0.0 0.02 14.8 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.10 KEY64744.1 - 0.0026 16.1 0.6 1.4 7.1 0.1 3.6 3 2 1 4 4 4 1 CAS/CSE protein, C-terminus DUF4042 PF13251.1 KEY64744.1 - 0.0036 16.7 0.6 19 4.6 0.0 5.4 5 1 2 7 7 7 0 Domain of unknown function (DUF4042) Proteasom_PSMB PF10508.4 KEY64744.1 - 0.0037 15.5 0.3 0.051 11.8 0.0 2.8 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit SEN1_N PF12726.2 KEY64744.1 - 0.0038 15.3 0.1 0.28 9.1 0.0 2.6 2 0 0 2 2 2 1 SEN1 N terminal V-ATPase_H_N PF03224.9 KEY64744.1 - 0.006 15.7 5.4 0.21 10.6 0.2 3.2 2 1 1 3 3 3 1 V-ATPase subunit H DUF3554 PF12074.3 KEY64744.1 - 0.019 14.3 0.3 3.5 6.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3554) Arm PF00514.18 KEY64744.1 - 0.02 14.7 7.2 3.4 7.6 0.0 5.0 5 0 0 5 5 4 0 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 KEY64744.1 - 0.035 14.0 0.4 13 5.8 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion DRIM PF07539.7 KEY64744.1 - 0.038 13.3 0.6 0.15 11.4 0.4 2.0 1 0 0 1 1 1 0 Down-regulated in metastasis TFCD_C PF12612.3 KEY64744.1 - 0.063 12.6 0.9 3.5 7.0 0.0 4.0 5 1 0 5 5 5 0 Tubulin folding cofactor D C terminal Cytokin_check_N PF10407.4 KEY64744.1 - 0.12 11.9 0.3 14 5.4 0.0 2.6 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus PUB PF09409.5 KEY64744.1 - 0.16 11.7 0.0 0.97 9.2 0.0 2.3 2 0 0 2 2 2 0 PUB domain CBS PF00571.23 KEY64746.1 - 2.9e-20 71.7 3.6 1.3e-07 31.2 0.1 5.5 5 1 0 5 5 5 5 CBS domain Tom37_C PF11801.3 KEY64747.1 - 0.07 12.9 0.4 0.077 12.8 0.3 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain Miff PF05644.6 KEY64747.1 - 0.14 11.7 3.7 0.27 10.8 2.5 1.4 1 1 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff SCIMP PF15050.1 KEY64748.1 - 0.16 11.8 0.6 0.63 9.9 0.4 1.9 1 0 0 1 1 1 0 SCIMP protein Glyco_hydro_17 PF00332.13 KEY64750.1 - 5.1e-06 25.7 0.0 8.3e-05 21.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Aminotran_1_2 PF00155.16 KEY64751.1 - 2.8e-38 131.8 0.0 3.8e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KEY64751.1 - 0.0031 15.8 0.0 0.0059 14.9 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme KdpC PF02669.10 KEY64751.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 K+-transporting ATPase, c chain DUF3755 PF12579.3 KEY64751.1 - 0.11 11.8 0.3 0.22 10.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) Mog1 PF04603.7 KEY64752.1 - 2e-19 69.9 0.0 2.5e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein SprT-like PF10263.4 KEY64753.1 - 1.8e-50 170.6 7.0 2.9e-50 169.9 4.8 1.3 1 0 0 1 1 1 1 SprT-like family HMG_box PF00505.14 KEY64753.1 - 0.0052 17.0 0.3 0.031 14.5 0.0 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box Zn-ribbon_8 PF09723.5 KEY64753.1 - 0.0092 15.9 1.1 0.022 14.7 0.7 1.6 1 0 0 1 1 1 1 Zinc ribbon domain Peptidase_M90 PF06167.7 KEY64753.1 - 0.062 12.6 0.5 0.11 11.8 0.4 1.4 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 Nucleo_P87 PF07267.6 KEY64753.1 - 2.5 6.6 7.0 4.7 5.7 4.9 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Glucan_synthase PF02364.10 KEY64754.1 - 0 1456.0 0.0 0 1455.4 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KEY64754.1 - 1.1e-40 138.1 0.3 3.6e-40 136.5 0.2 2.0 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Gaa1 PF04114.9 KEY64755.1 - 4.7e-104 348.8 1.4 6.1e-104 348.5 1.0 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component DUF334 PF03904.8 KEY64755.1 - 0.076 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Aconitase PF00330.15 KEY64756.1 - 4.6e-173 575.9 0.0 1e-172 574.8 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KEY64756.1 - 4.7e-45 152.8 0.0 8.2e-45 152.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Sdh5 PF03937.11 KEY64756.1 - 0.2 11.3 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase zf-C2H2_jaz PF12171.3 KEY64757.1 - 3.5e-08 33.3 0.1 8.6e-08 32.1 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEY64757.1 - 0.061 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DASH_Dam1 PF08653.5 KEY64758.1 - 6.5e-27 93.0 1.4 9.1e-27 92.6 1.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 CRAL_TRIO PF00650.15 KEY64759.1 - 6e-46 155.8 0.0 1.1e-45 155.0 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KEY64759.1 - 1.2e-13 50.9 0.1 3.3e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KEY64759.1 - 1e-11 44.9 0.0 2.6e-11 43.6 0.0 1.6 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain DUF2857 PF11198.3 KEY64759.1 - 0.027 13.9 0.0 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2857) Metal_resist PF13801.1 KEY64759.1 - 0.2 11.6 0.0 0.2 11.6 0.0 2.8 2 1 0 2 2 2 0 Heavy-metal resistance HIT PF01230.18 KEY64760.1 - 1.8e-21 76.4 0.1 2.2e-21 76.1 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KEY64760.1 - 3.3e-14 53.1 0.0 4.6e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KEY64760.1 - 1.5e-06 27.8 0.0 2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CSTF2_hinge PF14327.1 KEY64760.1 - 0.012 15.7 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 ICAT PF06384.6 KEY64760.1 - 0.036 13.8 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT Rhomboid PF01694.17 KEY64761.1 - 8.1e-14 51.8 9.5 8.1e-14 51.8 6.6 1.7 2 0 0 2 2 2 1 Rhomboid family DUF3487 PF11990.3 KEY64761.1 - 0.15 11.4 0.1 0.15 11.4 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) C_GCAxxG_C_C PF09719.5 KEY64761.1 - 0.17 11.6 0.1 0.56 10.0 0.1 1.7 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) DUF2830 PF11125.3 KEY64761.1 - 1.4 8.7 3.7 1.6 8.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2830) PCI PF01399.22 KEY64762.1 - 1.6e-10 41.1 0.0 4.1e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 PCI domain NAD_binding_10 PF13460.1 KEY64763.1 - 4.6e-17 62.6 0.0 6.8e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KEY64763.1 - 2.5e-16 59.6 0.0 3e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KEY64763.1 - 3.1e-14 52.9 0.0 5.3e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEY64763.1 - 3.4e-11 42.3 0.1 1.3e-10 40.4 0.1 1.8 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KEY64763.1 - 2.5e-06 26.6 0.0 0.00017 20.5 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KEY64763.1 - 0.00019 20.4 0.4 0.026 13.4 0.3 2.6 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.20 KEY64763.1 - 0.0034 17.3 0.0 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_synthase PF02540.12 KEY64763.1 - 0.038 12.8 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 NAD synthase Saccharop_dh PF03435.13 KEY64763.1 - 0.039 12.9 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase KR PF08659.5 KEY64763.1 - 0.068 12.8 0.0 0.74 9.4 0.0 2.3 2 0 0 2 2 2 0 KR domain ApbA PF02558.11 KEY64763.1 - 0.093 12.1 0.0 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA N6-adenineMlase PF10237.4 KEY64764.1 - 1.5e-56 190.5 0.0 1.9e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase UCH PF00443.24 KEY64765.1 - 2.1e-55 187.7 5.2 2.4e-55 187.5 3.1 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEY64765.1 - 3.6e-30 105.4 4.7 5.1e-30 104.9 3.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KEY64765.1 - 0.00037 20.5 0.2 0.00037 20.5 0.1 2.7 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein DUF4456 PF14644.1 KEY64765.1 - 0.039 13.1 0.0 0.21 10.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) Sec8_exocyst PF04048.9 KEY64765.1 - 0.1 12.2 0.1 0.26 10.9 0.1 1.6 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain zf-CCHC PF00098.18 KEY64765.1 - 3.3 7.7 8.0 28 4.8 0.0 4.2 4 0 0 4 4 4 0 Zinc knuckle Lactamase_B PF00753.22 KEY64766.1 - 2.3e-26 92.6 6.3 2.9e-26 92.3 4.4 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KEY64766.1 - 4.9e-06 26.2 0.4 6.8e-06 25.7 0.3 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KEY64766.1 - 1.9e-05 24.4 0.1 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Ytp1 PF10355.4 KEY64767.1 - 3.3e-110 367.5 7.6 4.8e-110 367.0 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KEY64767.1 - 2.4e-33 113.8 18.7 1e-30 105.3 4.7 3.6 3 0 0 3 3 3 3 Domain of unknown function (DUF2427) Rsa3 PF14615.1 KEY64768.1 - 5.1e-18 64.0 0.1 6e-18 63.8 0.1 1.1 1 0 0 1 1 1 1 Ribosome-assembly protein 3 UAF_Rrn10 PF05234.6 KEY64768.1 - 0.024 14.6 0.0 0.026 14.5 0.0 1.0 1 0 0 1 1 1 0 UAF complex subunit Rrn10 SNF2_N PF00176.18 KEY64769.1 - 2.1e-68 230.2 0.0 2.8e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 KEY64769.1 - 7.2e-62 208.6 3.0 2.8e-61 206.7 2.4 1.7 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 KEY64769.1 - 3.5e-13 49.1 0.0 2.7e-12 46.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEY64769.1 - 7.3e-06 25.9 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KEY64769.1 - 1.4e-05 24.0 0.0 0.00012 20.9 0.0 2.3 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 KEY64769.1 - 0.012 15.7 0.0 0.14 12.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain Mito_carr PF00153.22 KEY64770.1 - 1.4e-46 156.0 2.9 3.7e-19 68.2 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Wzy_C PF04932.10 KEY64770.1 - 0.068 12.9 0.2 0.28 10.9 0.0 1.8 1 1 0 2 2 2 0 O-Antigen ligase Glyco_transf_25 PF01755.12 KEY64771.1 - 0.017 14.7 0.0 0.5 9.9 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Bromodomain PF00439.20 KEY64772.1 - 3.3e-41 139.0 0.4 2.8e-21 75.2 0.3 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 KEY64772.1 - 1e-18 67.1 0.4 2e-18 66.2 0.3 1.5 1 0 0 1 1 1 1 BAH domain CDC45 PF02724.9 KEY64772.1 - 0.0022 16.1 4.6 0.0022 16.1 3.2 1.6 2 0 0 2 2 2 1 CDC45-like protein RRN3 PF05327.6 KEY64772.1 - 0.71 7.9 2.0 1.2 7.1 1.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 OTU PF02338.14 KEY64773.1 - 2.3e-12 47.5 0.0 4.1e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease DUF4589 PF15252.1 KEY64773.1 - 0.081 12.7 0.1 0.41 10.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4589) Peptidase_C65 PF10275.4 KEY64773.1 - 0.17 11.2 0.0 0.37 10.1 0.0 1.5 1 1 0 1 1 1 0 Peptidase C65 Otubain FmdA_AmdA PF03069.10 KEY64774.1 - 8.7e-154 511.6 0.0 1e-153 511.4 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family DUF2161 PF09929.4 KEY64774.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2161) EI24 PF07264.6 KEY64775.1 - 6e-06 25.8 18.6 0.00045 19.7 12.9 3.2 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Ni_hydr_CYTB PF01292.15 KEY64775.1 - 0.044 13.1 1.1 0.095 12.0 0.7 1.6 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Inp1 PF12634.2 KEY64776.1 - 2.4e-33 114.8 0.0 5e-33 113.8 0.0 1.6 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 RTA1 PF04479.8 KEY64777.1 - 1.7e-15 57.1 4.6 1.2e-14 54.3 3.2 1.9 1 1 0 1 1 1 1 RTA1 like protein MtN3_slv PF03083.11 KEY64777.1 - 0.0024 17.6 1.8 0.0072 16.1 1.3 1.8 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange IF2_N PF04760.10 KEY64777.1 - 0.043 13.4 0.0 0.089 12.4 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Xan_ur_permease PF00860.15 KEY64777.1 - 0.081 11.4 2.9 0.17 10.3 2.0 1.4 1 1 0 1 1 1 0 Permease family DUF1275 PF06912.6 KEY64777.1 - 0.29 10.3 7.0 0.16 11.1 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) ERF PF04404.7 KEY64780.1 - 0.082 12.4 0.4 0.11 12.0 0.3 1.1 1 0 0 1 1 1 0 ERF superfamily CPSase_L_D2 PF02786.12 KEY64781.1 - 3.5e-112 372.8 0.0 3e-84 281.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 KEY64781.1 - 3e-41 140.0 0.3 6.8e-41 138.8 0.2 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 KEY64781.1 - 1e-39 136.1 0.4 2.2e-22 79.7 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 KEY64781.1 - 1.1e-34 118.8 0.1 5.6e-16 58.6 0.0 3.0 3 0 0 3 3 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 KEY64781.1 - 2.9e-24 85.4 0.0 9.4e-09 34.4 0.0 3.6 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KEY64781.1 - 4.4e-22 78.2 0.1 5.4e-10 38.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KEY64781.1 - 1.4e-18 67.0 2.0 1.1e-09 37.9 0.1 2.9 3 0 0 3 3 3 2 D-ala D-ala ligase C-terminus RimK PF08443.6 KEY64781.1 - 1.7e-08 34.1 0.1 0.00016 21.1 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KEY64781.1 - 2.4e-06 27.4 0.2 0.038 13.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 KEY64781.1 - 5.9e-06 25.9 0.3 0.051 13.1 0.1 2.6 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 KEY64781.1 - 6.3e-06 25.5 1.0 0.015 14.4 0.0 3.3 3 0 0 3 3 3 2 ATP-grasp domain MGS PF02142.17 KEY64781.1 - 0.0055 16.6 0.0 0.02 14.8 0.0 2.0 1 0 0 1 1 1 1 MGS-like domain Pkinase PF00069.20 KEY64783.1 - 1.7e-44 151.9 0.0 2.6e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY64783.1 - 1.5e-20 73.3 0.0 2.2e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY64783.1 - 9.3e-05 21.5 0.0 0.00026 20.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KEY64783.1 - 0.05 12.9 0.2 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Per1 PF04080.8 KEY64784.1 - 1.1e-106 356.1 10.0 1.4e-106 355.7 6.9 1.1 1 0 0 1 1 1 1 Per1-like HLH PF00010.21 KEY64785.1 - 9.3e-13 47.6 0.2 2.1e-12 46.5 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Aldedh PF00171.17 KEY64786.1 - 2e-108 362.7 0.1 2.4e-108 362.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PhoD PF09423.5 KEY64787.1 - 2e-07 29.9 0.8 2.1e-06 26.5 0.1 2.3 3 0 0 3 3 3 2 PhoD-like phosphatase DUF1765 PF08578.5 KEY64788.1 - 1.1e-42 145.0 7.1 1.1e-42 145.0 4.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) Zn_clus PF00172.13 KEY64789.1 - 7.4e-05 22.5 5.9 0.00034 20.4 4.1 2.0 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo70 PF03081.10 KEY64789.1 - 0.13 11.0 0.1 1.1 7.9 0.0 2.0 2 0 0 2 2 2 0 Exo70 exocyst complex subunit Cutinase PF01083.17 KEY64790.1 - 9.5e-52 175.3 0.3 1.1e-51 175.0 0.2 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KEY64790.1 - 0.0035 16.7 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 KEY64790.1 - 0.0067 16.2 0.0 0.0093 15.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Lipase_3 PF01764.20 KEY64790.1 - 0.034 13.7 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_1 PF00561.15 KEY64790.1 - 0.064 12.8 0.1 2.4 7.6 0.1 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.3 KEY64790.1 - 0.1 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Kelch_5 PF13854.1 KEY64791.1 - 2.2e-16 59.3 11.0 2.9e-06 27.0 0.4 5.2 4 1 0 4 4 4 4 Kelch motif Kelch_4 PF13418.1 KEY64791.1 - 1.5e-14 53.4 3.6 0.0019 17.9 0.0 6.4 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KEY64791.1 - 9e-12 44.6 6.1 0.014 15.5 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 KEY64791.1 - 6.9e-10 38.8 13.0 0.01 15.9 0.0 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.10 KEY64791.1 - 8.1e-08 31.7 2.6 0.0035 17.0 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 KEY64791.1 - 1.6e-06 27.5 3.9 0.033 13.7 0.0 4.9 5 0 0 5 5 5 2 Kelch motif Metallophos PF00149.23 KEY64792.1 - 1.7e-11 43.9 2.6 1.7e-11 43.9 1.8 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase CMV_1a PF12467.3 KEY64792.1 - 0.064 13.6 7.4 0.93 9.8 0.0 3.2 3 0 0 3 3 3 0 Cucumber mosaic virus 1a protein family NPR3 PF03666.8 KEY64792.1 - 4.3 5.7 5.8 7.4 4.9 4.0 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1676 PF07898.8 KEY64792.1 - 9.6 6.5 8.7 17 5.7 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1676) GCV_T PF01571.16 KEY64794.1 - 2.5e-54 183.8 0.0 3.3e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KEY64794.1 - 3.1e-21 75.2 1.4 5.6e-21 74.3 1.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain V-ATPase_H_N PF03224.9 KEY64795.1 - 1.3e-72 244.6 0.0 8.9e-72 241.8 0.0 1.9 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 KEY64795.1 - 2.8e-39 133.7 1.0 6.7e-39 132.4 0.0 2.2 3 0 0 3 3 3 1 V-ATPase subunit H HEAT_2 PF13646.1 KEY64795.1 - 0.013 15.7 4.9 0.15 12.3 0.0 3.7 4 0 0 4 4 4 0 HEAT repeats HEAT PF02985.17 KEY64795.1 - 0.033 14.2 0.1 1.3 9.3 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat DUF3730 PF12530.3 KEY64795.1 - 0.053 13.4 2.8 5.4 6.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) Med4 PF10018.4 KEY64795.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 HEAT_EZ PF13513.1 KEY64795.1 - 0.19 12.2 4.5 8.3 7.0 0.0 4.3 4 1 1 5 5 5 0 HEAT-like repeat Transposase_20 PF02371.11 KEY64796.1 - 0.0084 16.1 4.3 0.023 14.8 3.0 1.7 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DUF1191 PF06697.7 KEY64796.1 - 0.097 11.4 0.3 0.4 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) DUF1183 PF06682.7 KEY64796.1 - 0.65 9.5 18.4 0.046 13.3 4.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) DUF4131 PF13567.1 KEY64796.1 - 6.5 6.1 6.8 37 3.6 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Ribosomal_L6 PF00347.18 KEY64797.1 - 1.4e-25 89.5 7.8 1.1e-12 48.2 1.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Vps26 PF03643.10 KEY64798.1 - 1.9e-129 430.3 0.5 2.2e-129 430.1 0.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KEY64798.1 - 0.00015 21.6 0.0 0.11 12.2 0.0 3.6 2 1 1 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Nup160 PF11715.3 KEY64799.1 - 6.4e-127 423.9 0.2 8.1e-127 423.6 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Rad51 PF08423.6 KEY64800.1 - 4.9e-137 454.9 0.0 6.1e-137 454.6 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KEY64800.1 - 3.4e-13 49.4 0.0 5.1e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 KEY64800.1 - 2.2e-07 30.9 1.2 5.9e-07 29.5 0.2 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain KaiC PF06745.8 KEY64800.1 - 1.2e-06 27.8 0.0 2.2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 KaiC RecA PF00154.16 KEY64800.1 - 1.8e-06 27.2 0.0 2.5e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein DnaB_C PF03796.10 KEY64800.1 - 0.017 14.0 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 KEY64800.1 - 0.14 10.9 0.0 0.27 10.0 0.0 1.4 1 0 0 1 1 1 0 PAXNEB protein HSP20 PF00011.16 KEY64801.1 - 1.8e-18 66.3 0.8 1.7e-12 47.1 0.1 2.1 2 0 0 2 2 2 2 Hsp20/alpha crystallin family SOG2 PF10428.4 KEY64801.1 - 0.039 12.6 0.1 0.62 8.6 0.0 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein DUF4432 PF14486.1 KEY64801.1 - 0.04 12.4 0.0 0.065 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) YTH PF04146.10 KEY64802.1 - 3e-56 188.8 0.0 4.4e-56 188.3 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain Proteasome PF00227.21 KEY64803.1 - 2.4e-28 98.7 0.5 5.8e-28 97.4 0.1 1.7 2 1 0 2 2 2 1 Proteasome subunit PI3_PI4_kinase PF00454.22 KEY64804.1 - 6.4e-37 127.2 0.0 2.1e-36 125.5 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KEY64804.1 - 1.2e-22 79.9 0.0 3.5e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Cation_efflux PF01545.16 KEY64805.1 - 1.6e-33 116.0 10.2 1.9e-33 115.7 7.1 1.1 1 0 0 1 1 1 1 Cation efflux family HET PF06985.6 KEY64806.1 - 9.9e-21 74.3 0.3 3.6e-20 72.5 0.0 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Arginosuc_synth PF00764.14 KEY64806.1 - 0.073 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase HET PF06985.6 KEY64807.1 - 1.8e-05 24.9 3.2 0.012 15.8 2.2 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DnaJ PF00226.26 KEY64808.1 - 1.2e-17 63.3 0.0 2.4e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Laminin_I PF06008.9 KEY64809.1 - 0.0029 16.9 2.4 0.0039 16.5 1.7 1.2 1 0 0 1 1 1 1 Laminin Domain I CENP-F_leu_zip PF10473.4 KEY64809.1 - 0.0034 17.2 5.7 0.0034 17.2 4.0 2.0 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nup54 PF13874.1 KEY64809.1 - 0.024 14.2 0.9 0.024 14.2 0.6 2.0 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 AAA_13 PF13166.1 KEY64809.1 - 0.057 11.8 0.4 0.075 11.4 0.3 1.1 1 0 0 1 1 1 0 AAA domain FAM47 PF14642.1 KEY64809.1 - 0.11 11.7 1.9 0.2 10.9 1.3 1.3 1 0 0 1 1 1 0 FAM47 family DUF972 PF06156.8 KEY64809.1 - 0.13 12.5 1.3 1.7 9.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) RmuC PF02646.11 KEY64809.1 - 0.15 10.8 0.7 0.28 9.9 0.1 1.6 1 1 1 2 2 2 0 RmuC family APG6 PF04111.7 KEY64809.1 - 0.16 11.0 1.7 0.24 10.3 1.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF812 PF05667.6 KEY64809.1 - 0.18 10.2 1.8 0.26 9.7 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Tropomyosin_1 PF12718.2 KEY64809.1 - 0.75 9.6 10.9 10 5.9 7.7 2.2 1 1 0 1 1 1 0 Tropomyosin like Spc7 PF08317.6 KEY64809.1 - 1.1 7.8 4.6 15 4.0 1.2 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein OEP PF02321.13 KEY64809.1 - 1.1 8.8 8.0 0.052 13.1 1.8 1.6 2 0 0 2 2 2 0 Outer membrane efflux protein Prefoldin_2 PF01920.15 KEY64809.1 - 3 7.6 7.7 14 5.5 0.0 3.1 2 2 1 3 3 3 0 Prefoldin subunit TMF_DNA_bd PF12329.3 KEY64809.1 - 8.4 6.2 8.1 0.86 9.4 1.6 2.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2414 PF10309.4 KEY64810.1 - 1.8e-21 75.5 0.1 3.2e-21 74.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 KEY64810.1 - 0.02 14.8 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 RNA binding domain NAD_binding_1 PF00175.16 KEY64811.1 - 4.7e-07 30.3 0.0 0.03 14.9 0.0 2.2 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KEY64811.1 - 0.00032 20.6 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 2 Ferric reductase NAD binding domain DUF3596 PF12167.3 KEY64811.1 - 0.14 11.6 0.0 0.35 10.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) Adaptin_N PF01602.15 KEY64812.1 - 2.2e-141 471.7 0.7 2.6e-141 471.5 0.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 KEY64812.1 - 2.7e-21 76.0 0.0 7.8e-21 74.5 0.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 KEY64812.1 - 1.1e-06 28.8 0.5 0.092 13.0 0.0 4.1 3 2 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 KEY64812.1 - 0.00024 20.9 1.6 0.057 13.2 0.8 3.3 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KEY64812.1 - 0.00098 19.0 2.6 13 6.1 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 KEY64812.1 - 0.0058 17.0 2.1 12 6.5 0.1 4.6 4 1 1 5 5 5 1 HEAT-like repeat TIP120 PF08623.5 KEY64812.1 - 0.0089 15.6 0.4 0.049 13.2 0.0 2.4 2 1 0 2 2 2 1 TATA-binding protein interacting (TIP20) Arm PF00514.18 KEY64812.1 - 0.06 13.1 0.2 90 3.1 0.1 4.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat EF-hand_1 PF00036.27 KEY64813.1 - 2.8e-41 135.6 12.8 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KEY64813.1 - 1.7e-36 124.1 5.8 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KEY64813.1 - 8.5e-35 118.1 12.2 6.8e-16 57.6 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KEY64813.1 - 1.2e-30 102.6 8.0 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KEY64813.1 - 5.2e-26 88.7 9.7 1.4e-06 27.3 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KEY64813.1 - 1.3e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KEY64813.1 - 2.6e-09 36.7 1.9 0.00056 19.6 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KEY64813.1 - 1.5e-08 34.6 0.1 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 KEY64813.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 KEY64813.1 - 4.4e-07 29.7 2.1 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 KEY64813.1 - 0.00014 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 KEY64813.1 - 0.00023 20.7 0.2 0.075 12.5 0.0 2.7 1 1 1 3 3 3 1 Caleosin related protein Tenui_NCP PF04876.7 KEY64813.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 KEY64813.1 - 0.0026 17.7 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 KEY64813.1 - 0.0083 16.4 1.3 2.5 8.4 0.0 2.5 1 1 2 3 3 3 2 Toprim-like DUF3349 PF11829.3 KEY64813.1 - 0.021 15.2 0.4 12 6.4 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 KEY64813.1 - 0.14 11.8 2.5 0.83 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 KEY64813.1 - 0.38 10.3 4.1 0.99 9.0 1.1 2.2 1 1 0 2 2 2 0 RloB-like protein PB1 PF00564.19 KEY64813.1 - 0.45 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain SNARE PF05739.14 KEY64814.1 - 3.4e-19 68.2 2.9 3.4e-19 68.2 2.0 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KEY64814.1 - 1.8e-12 47.3 7.1 3e-12 46.6 0.4 2.4 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 KEY64814.1 - 0.067 12.7 10.2 0.18 11.3 0.6 2.4 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain HeLo PF14479.1 KEY64814.1 - 0.086 12.5 5.2 0.094 12.4 0.9 2.3 2 0 0 2 2 2 0 Prion-inhibition and propagation ATG16 PF08614.6 KEY64814.1 - 1.5 8.5 11.5 19 5.0 6.6 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TMPIT PF07851.8 KEY64814.1 - 2.1 7.3 4.4 5.7 5.9 0.8 2.1 2 0 0 2 2 2 0 TMPIT-like protein IncA PF04156.9 KEY64814.1 - 2.3 7.7 11.0 4.3 6.8 0.2 3.4 3 1 0 3 3 3 0 IncA protein HAUS-augmin3 PF14932.1 KEY64814.1 - 4.1 6.5 12.2 0.19 10.8 1.5 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 PPR_3 PF13812.1 KEY64815.1 - 1e-05 25.4 0.1 2.8 8.4 0.0 4.9 4 0 0 4 4 4 2 Pentatricopeptide repeat domain SH PF01445.12 KEY64815.1 - 0.07 12.8 0.1 0.16 11.6 0.1 1.6 1 0 0 1 1 1 0 Viral small hydrophobic protein COX7a PF02238.10 KEY64816.1 - 0.015 15.0 0.4 0.025 14.2 0.3 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIIa Clathrin_lg_ch PF01086.12 KEY64817.1 - 3.6e-69 233.1 4.4 4.1e-69 232.9 3.1 1.0 1 0 0 1 1 1 1 Clathrin light chain rve_3 PF13683.1 KEY64817.1 - 0.1 12.1 0.6 0.21 11.1 0.4 1.5 1 0 0 1 1 1 0 Integrase core domain DUF4407 PF14362.1 KEY64817.1 - 1.1 8.1 8.6 0.64 8.9 3.1 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) ATP-synt_B PF00430.13 KEY64817.1 - 2.1 8.1 8.8 3.2 7.5 6.1 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) CTD_bind PF04818.8 KEY64818.1 - 3.1e-20 72.1 1.0 5.1e-20 71.4 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Antimicrobial10 PF08105.6 KEY64818.1 - 0.023 14.3 0.1 0.08 12.5 0.1 1.9 1 0 0 1 1 1 0 Metchnikowin family CTK3 PF12243.3 KEY64818.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 DUF3277 PF11681.3 KEY64818.1 - 0.1 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) ABC_membrane PF00664.18 KEY64819.1 - 2.2e-43 148.6 11.3 2.9e-43 148.2 7.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KEY64819.1 - 7.9e-34 116.8 0.2 3.1e-33 114.9 0.0 2.1 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 KEY64819.1 - 0.00045 19.5 0.4 0.011 14.9 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEY64819.1 - 0.00051 20.0 0.5 0.66 9.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KEY64819.1 - 0.00058 19.9 0.1 0.0018 18.3 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KEY64819.1 - 0.0026 18.5 0.0 0.0065 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEY64819.1 - 0.0047 17.0 0.1 0.03 14.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KEY64819.1 - 0.0099 16.0 0.2 0.098 12.8 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 KEY64819.1 - 0.013 14.0 0.1 0.024 13.2 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class SbcCD_C PF13558.1 KEY64819.1 - 0.016 15.1 1.2 0.17 11.8 0.8 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 KEY64819.1 - 0.017 14.8 0.0 0.071 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 KEY64819.1 - 0.022 14.2 0.0 0.06 12.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 KEY64819.1 - 0.15 11.4 0.4 0.87 8.9 0.3 2.0 1 1 0 1 1 1 0 AAA domain Hydrolase_4 PF12146.3 KEY64820.1 - 2.9e-20 71.8 0.0 5.5e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 KEY64820.1 - 1.1e-19 71.1 1.9 1.4e-19 70.9 1.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY64820.1 - 4.3e-17 62.2 0.3 6.6e-17 61.6 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY64820.1 - 4.8e-05 23.0 0.1 6.6e-05 22.5 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEY64820.1 - 0.0013 18.0 0.2 0.68 9.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase PF07224.6 KEY64820.1 - 0.0048 15.7 0.0 0.0068 15.2 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 KEY64820.1 - 0.0072 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.15 KEY64820.1 - 0.054 13.7 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.20 KEY64820.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF1749 PF08538.5 KEY64820.1 - 0.11 11.3 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Cation_efflux PF01545.16 KEY64821.1 - 3.2e-28 98.6 5.5 3.8e-28 98.3 3.8 1.1 1 0 0 1 1 1 1 Cation efflux family Glyco_transf_8 PF01501.15 KEY64822.1 - 1.4e-32 113.0 0.0 3e-32 111.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KEY64822.1 - 0.0095 15.3 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative zf-rbx1 PF12678.2 KEY64823.1 - 7.6e-12 45.1 1.9 1.4e-11 44.2 1.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KEY64823.1 - 3.4e-11 42.8 4.6 6.4e-11 41.9 3.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KEY64823.1 - 5.5e-07 29.1 6.1 8e-06 25.4 4.5 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY64823.1 - 5.2e-06 26.0 2.6 1e-05 25.1 1.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KEY64823.1 - 2.2e-05 24.0 3.9 3.8e-05 23.2 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEY64823.1 - 0.00014 21.6 0.7 0.00043 20.0 0.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KEY64823.1 - 0.00041 20.3 5.8 0.0016 18.3 4.1 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KEY64823.1 - 0.00074 19.1 3.8 0.0017 18.0 2.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.1 KEY64823.1 - 0.017 14.6 0.8 0.017 14.6 0.5 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 KEY64823.1 - 0.08 12.8 1.2 0.17 11.7 0.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KEY64823.1 - 0.43 10.1 3.1 0.29 10.7 0.5 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 KEY64823.1 - 1.1 9.3 3.6 2.5 8.1 1.7 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 KEY64823.1 - 6.4 6.8 5.8 23 5.1 4.0 1.9 1 1 0 1 1 1 0 RING-variant domain zf-C2H2_4 PF13894.1 KEY64826.1 - 0.00018 21.5 15.6 0.14 12.5 0.0 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY64826.1 - 0.0002 21.5 19.3 1.2 9.6 0.5 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KEY64826.1 - 0.0013 18.5 1.4 0.076 12.9 0.7 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger DUF629 PF04780.7 KEY64826.1 - 0.043 12.3 0.9 0.086 11.3 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF629) DUF230 PF03003.11 KEY64826.1 - 0.063 12.8 0.2 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Poxvirus proteins of unknown function Rav1p_C PF12234.3 KEY64826.1 - 0.24 9.5 0.0 0.34 9.0 0.0 1.1 1 0 0 1 1 1 0 RAVE protein 1 C terminal CcoS PF03597.10 KEY64827.1 - 0.84 9.1 3.9 1.7 8.1 2.7 1.5 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type FLO_LFY PF01698.11 KEY64827.1 - 3.1 6.5 14.7 2.6 6.7 2.2 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein YdfA_immunity PF12127.3 KEY64828.1 - 0.08 11.8 4.2 0.12 11.2 2.9 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial Exo_endo_phos PF03372.18 KEY64829.1 - 7.9e-12 45.6 0.6 9.8e-12 45.3 0.4 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family V-SNARE_C PF12352.3 KEY64830.1 - 0.027 14.5 2.5 0.038 14.0 0.4 2.3 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus bZIP_1 PF00170.16 KEY64831.1 - 7.6e-06 25.7 6.7 7.6e-06 25.7 4.6 1.9 2 0 0 2 2 2 1 bZIP transcription factor DUF4407 PF14362.1 KEY64831.1 - 0.1 11.5 4.4 0.18 10.7 2.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) bZIP_2 PF07716.10 KEY64831.1 - 0.53 10.1 9.8 0.23 11.2 4.3 2.1 2 0 0 2 2 2 0 Basic region leucine zipper Glyco_hydro_16 PF00722.16 KEY64832.1 - 9.8e-12 44.5 1.1 1.4e-11 44.0 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WW PF00397.21 KEY64833.1 - 9.8e-06 25.3 2.1 2.2e-05 24.2 1.5 1.6 1 0 0 1 1 1 1 WW domain Selenoprotein_S PF06936.6 KEY64833.1 - 2.8 7.4 10.4 1.9 7.9 3.1 2.2 2 0 0 2 2 2 0 Selenoprotein S (SelS) RIX1 PF08167.7 KEY64834.1 - 7.6e-41 139.5 1.0 1.6e-40 138.5 0.7 1.6 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis TPR_2 PF07719.12 KEY64835.1 - 1.8e-08 33.6 11.4 0.35 10.8 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEY64835.1 - 2.3e-06 27.7 22.4 0.36 11.5 0.2 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEY64835.1 - 7e-05 22.2 9.7 1.6 8.4 0.3 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEY64835.1 - 0.00011 21.7 11.3 1.4 8.6 0.8 5.7 5 1 1 6 6 6 2 TPR repeat TPR_16 PF13432.1 KEY64835.1 - 0.00087 19.8 20.8 3.9 8.2 0.0 6.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEY64835.1 - 0.021 14.6 9.6 0.029 14.1 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 KEY64835.1 - 0.032 14.4 8.4 0.77 10.1 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_21 PF09976.4 KEY64835.1 - 0.6 10.0 5.4 18 5.2 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEY64835.1 - 0.93 10.0 7.8 14 6.3 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEY64835.1 - 5.3 7.0 11.5 26 4.9 0.0 5.9 7 1 1 8 8 8 0 Tetratricopeptide repeat DUF2058 PF09831.4 KEY64836.1 - 1.1 9.1 9.9 1.7 8.4 6.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF4200 PF13863.1 KEY64836.1 - 1.1 9.1 12.0 2 8.3 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Xpo1 PF08389.7 KEY64837.1 - 4.7e-34 117.4 0.1 3e-33 114.8 0.0 2.5 2 0 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.17 KEY64837.1 - 0.00028 20.6 0.1 1.2 9.4 0.0 4.1 4 0 0 4 4 4 2 HEAT repeat CHAD PF05235.9 KEY64837.1 - 0.0044 16.6 0.1 0.52 9.8 0.0 3.1 3 0 0 3 3 3 1 CHAD domain Iso_dh PF00180.15 KEY64839.1 - 3.3e-130 434.0 0.0 4e-130 433.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RTA1 PF04479.8 KEY64840.1 - 2.9e-44 151.2 8.5 2.9e-44 151.2 5.9 1.3 2 0 0 2 2 2 1 RTA1 like protein Cytochrom_B_N_2 PF13631.1 KEY64840.1 - 1.6 8.5 12.7 12 5.6 8.5 2.5 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Peptidase_M18 PF02127.10 KEY64841.1 - 2e-168 560.4 0.0 4.4e-168 559.2 0.0 1.5 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 KEY64841.1 - 4.3e-05 22.4 0.0 0.0005 18.9 0.0 2.3 2 1 1 3 3 3 1 M42 glutamyl aminopeptidase Whi5 PF08528.6 KEY64842.1 - 4e-08 32.6 0.1 6.2e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Whi5 like Peptidase_C70 PF12385.3 KEY64844.1 - 0.064 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 Aldedh PF00171.17 KEY64846.1 - 8.4e-166 551.8 0.0 1e-165 551.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family bZIP_1 PF00170.16 KEY64847.1 - 0.0023 17.8 11.6 0.0036 17.2 8.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KEY64847.1 - 0.0092 15.7 13.8 0.014 15.1 9.6 1.3 1 0 0 1 1 1 1 Basic region leucine zipper EURL PF06937.6 KEY64847.1 - 0.11 11.8 2.3 0.17 11.2 1.6 1.1 1 0 0 1 1 1 0 EURL protein Tho2 PF11262.3 KEY64847.1 - 0.33 9.9 4.1 0.44 9.5 2.8 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Phlebovirus_NSM PF07246.6 KEY64847.1 - 0.54 9.3 3.3 0.84 8.7 2.3 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M PNP_UDP_1 PF01048.15 KEY64848.1 - 1.4e-13 50.3 0.0 3.9e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Phosphorylase superfamily TPR_12 PF13424.1 KEY64848.1 - 1.1e-11 44.5 0.2 4.2e-11 42.6 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 KEY64848.1 - 2.4e-09 36.7 0.0 0.00019 21.2 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat NB-ARC PF00931.17 KEY64848.1 - 8.1e-06 24.8 0.0 0.0083 15.0 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain TPR_11 PF13414.1 KEY64848.1 - 2.9e-05 23.6 0.3 6.5e-05 22.4 0.2 1.6 1 0 0 1 1 1 1 TPR repeat AAA_22 PF13401.1 KEY64848.1 - 0.00081 19.5 0.0 0.0024 18.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain TPR_7 PF13176.1 KEY64848.1 - 0.007 16.0 0.2 0.055 13.2 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEY64848.1 - 0.0079 16.3 0.4 0.36 11.1 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF1541 PF07563.6 KEY64848.1 - 0.0083 15.7 0.3 0.019 14.6 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1541) TPR_4 PF07721.9 KEY64848.1 - 0.0093 16.3 0.1 0.59 10.7 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEY64848.1 - 0.032 14.1 0.9 1 9.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEY64848.1 - 0.098 12.4 0.2 2.2 8.2 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat HET PF06985.6 KEY64849.1 - 2.5e-13 50.3 1.3 2.5e-13 50.3 0.9 2.2 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF1241 PF06840.6 KEY64849.1 - 1.1e-05 24.7 2.6 4.1 6.6 0.0 5.3 1 1 2 5 5 5 4 Protein of unknown function (DUF1241) TPR_12 PF13424.1 KEY64849.1 - 7.4e-05 22.6 0.1 0.00026 20.8 0.1 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat Clr2 PF10383.4 KEY64849.1 - 1.1 9.2 6.1 1e+02 2.8 0.1 4.7 1 1 1 4 4 4 0 Transcription-silencing protein Clr2 zf-C2H2_4 PF13894.1 KEY64852.1 - 4.2e-07 29.8 5.7 0.067 13.5 0.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY64852.1 - 5.4e-06 26.4 6.6 0.07 13.5 0.0 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KEY64852.1 - 0.012 15.8 5.1 0.43 10.9 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Pkinase PF00069.20 KEY64854.1 - 1e-28 100.1 0.0 1.4e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY64854.1 - 3.6e-09 36.0 0.0 7.4e-09 35.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEY64854.1 - 0.00025 20.8 0.0 0.016 14.9 0.0 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEY64854.1 - 0.031 13.2 0.0 0.37 9.7 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 KEY64854.1 - 0.1 11.6 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fes1 PF08609.5 KEY64855.1 - 0.08 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 DDE_Tnp_1_7 PF13843.1 KEY64856.1 - 1.3e-44 152.6 0.0 1.9e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.1 KEY64856.1 - 0.0003 21.1 5.6 0.0003 21.1 3.9 2.1 2 0 0 2 2 2 1 DDE_Tnp_1-like zinc-ribbon Arylsulfotrans PF05935.6 KEY64856.1 - 0.081 11.4 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) APH PF01636.18 KEY64858.1 - 8.2e-05 22.4 0.0 0.00012 21.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family AAA PF00004.24 KEY64860.1 - 3.7e-18 65.9 0.0 8.7e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEY64860.1 - 0.00017 21.3 0.2 0.0006 19.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEY64860.1 - 0.00041 20.4 0.4 0.005 16.9 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 KEY64860.1 - 0.00058 19.8 0.1 0.0074 16.2 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 KEY64860.1 - 0.0014 18.2 0.1 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEY64860.1 - 0.0032 17.7 0.0 0.011 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEY64860.1 - 0.0044 17.8 0.1 0.017 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KEY64860.1 - 0.038 13.0 0.0 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KEY64860.1 - 0.04 14.0 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.16 KEY64860.1 - 0.045 12.9 0.1 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KEY64860.1 - 0.06 12.7 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.9 KEY64860.1 - 0.12 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) ZF-HD_dimer PF04770.7 KEY64862.1 - 0.024 14.6 0.1 13 5.9 0.0 3.2 3 0 0 3 3 3 0 ZF-HD protein dimerisation region Pkinase PF00069.20 KEY64863.1 - 1.2e-10 40.9 0.0 1.9e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY64863.1 - 2.4e-05 23.5 0.0 2.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KEY64863.1 - 3.5e-05 23.2 0.0 5.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KEY64863.1 - 4.7e-05 23.2 0.0 0.00053 19.8 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KEY64863.1 - 0.00033 19.7 0.0 0.00049 19.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KEY64863.1 - 0.007 15.9 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 KEY64863.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Kinase-like RanGAP1_C PF07834.6 KEY64864.1 - 0.11 11.9 0.0 3 7.2 0.0 2.2 1 1 1 2 2 2 0 RanGAP1 C-terminal domain Pectate_lyase PF03211.8 KEY64865.1 - 3.2e-81 271.8 5.3 4e-81 271.5 3.7 1.0 1 0 0 1 1 1 1 Pectate lyase RAI16-like PF10257.4 KEY64867.1 - 6.9e-76 255.4 2.6 1.1e-75 254.7 1.8 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Dynamin_N PF00350.18 KEY64868.1 - 1.1e-12 48.0 0.1 5e-12 45.9 0.0 2.2 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 KEY64868.1 - 1.4e-05 25.0 0.0 0.0014 18.5 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 KEY64868.1 - 0.00012 22.3 0.1 0.00062 20.0 0.0 2.2 2 0 0 2 2 2 1 ABC transporter Miro PF08477.8 KEY64868.1 - 0.00038 20.9 0.0 0.0011 19.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 KEY64868.1 - 0.0014 17.7 0.0 0.0044 16.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KEY64868.1 - 0.006 16.5 1.7 0.13 12.2 0.1 3.3 3 1 0 3 3 3 1 AAA ATPase domain ORF6C PF10552.4 KEY64868.1 - 0.039 13.6 0.1 0.32 10.7 0.0 2.7 3 0 0 3 3 3 0 ORF6C domain DUF87 PF01935.12 KEY64868.1 - 0.051 13.3 0.1 0.051 13.3 0.1 3.8 3 1 0 4 4 4 0 Domain of unknown function DUF87 DUF2207 PF09972.4 KEY64868.1 - 0.41 9.1 1.8 9.6 4.6 0.2 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Thioesterase PF00975.15 KEY64869.1 - 2.2e-13 50.9 0.0 5.4e-12 46.4 0.0 2.7 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 KEY64869.1 - 1.4e-05 25.0 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY64869.1 - 0.00021 21.0 0.0 0.00045 20.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KEY64869.1 - 0.022 14.2 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 KEY64869.1 - 0.039 13.5 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KEY64869.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold CLP_protease PF00574.18 KEY64870.1 - 2e-67 226.3 0.4 2.7e-67 225.9 0.3 1.1 1 0 0 1 1 1 1 Clp protease ILVD_EDD PF00920.16 KEY64872.1 - 2.3e-210 699.4 0.9 2.7e-210 699.2 0.6 1.0 1 0 0 1 1 1 1 Dehydratase family Acyltransferase PF01553.16 KEY64873.1 - 6.8e-05 22.3 0.0 0.00016 21.1 0.0 1.6 2 0 0 2 2 2 1 Acyltransferase Kinesin PF00225.18 KEY64874.1 - 2.7e-105 351.7 1.3 7.1e-105 350.4 0.9 1.7 1 0 0 1 1 1 1 Kinesin motor domain WEMBL PF05701.6 KEY64874.1 - 2.3e-06 26.3 35.3 1.8e-05 23.4 13.1 2.4 1 1 1 2 2 2 2 Weak chloroplast movement under blue light LPP PF04728.8 KEY64874.1 - 0.015 15.0 2.3 0.31 10.8 0.6 3.3 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF972 PF06156.8 KEY64874.1 - 2.1 8.6 36.1 0.55 10.5 2.4 6.5 3 1 3 6 6 6 0 Protein of unknown function (DUF972) ADIP PF11559.3 KEY64874.1 - 2.3 8.0 42.4 0.95 9.3 7.1 3.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 KEY64874.1 - 2.7 7.5 51.3 5.1 6.6 13.8 3.5 2 1 1 3 3 3 0 IncA protein Baculo_PEP_C PF04513.7 KEY64874.1 - 3 7.6 7.2 9.2 6.0 1.2 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 KEY64874.1 - 9.2 5.3 12.0 2.3 7.3 0.7 3.2 2 1 2 4 4 4 0 Reovirus sigma C capsid protein HhH-GPD PF00730.20 KEY64876.1 - 1.3e-09 38.2 0.0 2.7e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein 5_nucleotid_C PF02872.13 KEY64878.1 - 3.6e-33 114.7 0.0 6.9e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KEY64878.1 - 3.7e-16 59.1 0.3 5.4e-16 58.5 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEY64878.1 - 0.00015 21.6 0.0 0.00043 20.1 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain YmdB PF13277.1 KEY64878.1 - 0.00049 19.2 0.0 0.00084 18.4 0.0 1.3 1 0 0 1 1 1 1 YmdB-like protein MFS_1 PF07690.11 KEY64879.1 - 4.3e-43 147.3 55.1 5.8e-36 123.9 23.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Acyltransferase PF01553.16 KEY64880.1 - 1.5e-24 85.9 0.0 2.1e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase 7TM_GPCR_Srt PF10321.4 KEY64880.1 - 0.017 13.8 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt NAD_kinase PF01513.16 KEY64881.1 - 1.1e-40 139.2 0.0 4.8e-40 137.1 0.0 1.8 1 1 0 1 1 1 1 ATP-NAD kinase PLA2_B PF01735.13 KEY64883.1 - 1.8e-175 583.8 0.0 2.1e-175 583.6 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain GFO_IDH_MocA PF01408.17 KEY64884.1 - 5.3e-21 75.3 0.0 1e-20 74.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KEY64884.1 - 7e-12 45.1 0.0 1.6e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 KEY64884.1 - 0.0042 17.4 0.0 0.0091 16.3 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 KEY64884.1 - 0.088 13.1 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Peptidase_M28 PF04389.12 KEY64885.1 - 5.4e-32 110.9 0.1 1.2e-31 109.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KEY64885.1 - 0.00033 20.2 0.1 0.00039 19.9 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 KEY64885.1 - 0.011 14.5 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase MFS_1 PF07690.11 KEY64886.1 - 7.6e-32 110.3 26.1 1e-31 109.9 18.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-CCHC PF00098.18 KEY64886.1 - 6e-11 41.7 10.3 3.8e-05 23.4 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 KEY64886.1 - 2.3e-08 33.5 0.1 4.5e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 KEY64886.1 - 4.9e-06 26.1 6.3 0.00083 19.0 2.1 2.4 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 KEY64886.1 - 2.6e-05 23.7 0.2 6.3e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 KEY64886.1 - 0.0041 16.7 6.3 0.48 10.1 0.6 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 KEY64886.1 - 0.0063 16.1 7.9 0.34 10.6 0.4 2.7 1 1 1 2 2 2 2 Zinc knuckle Peptidase_M16_C PF05193.16 KEY64886.1 - 2.5 7.7 5.2 14 5.3 0.2 2.9 2 1 0 2 2 2 0 Peptidase M16 inactive domain Lipase_3 PF01764.20 KEY64887.1 - 2.5e-18 66.0 0.0 4.8e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) TauD PF02668.11 KEY64890.1 - 8e-23 81.4 0.1 1e-22 81.0 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KEY64890.1 - 0.0026 16.7 0.1 0.0045 15.9 0.1 1.3 1 0 0 1 1 1 1 CsiD Fungal_trans PF04082.13 KEY64891.1 - 1.9e-11 43.3 2.4 4.6e-11 42.0 1.7 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY64891.1 - 2.7e-10 39.9 10.6 4.1e-10 39.3 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo_endo_phos PF03372.18 KEY64892.1 - 1.9e-17 64.0 0.2 3.1e-17 63.3 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DCP1 PF06058.8 KEY64893.1 - 6.9e-19 68.1 0.0 9.9e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 Dcp1-like decapping family BAR PF03114.13 KEY64894.1 - 4.5e-63 212.8 2.7 5.5e-63 212.5 1.9 1.1 1 0 0 1 1 1 1 BAR domain Pept_tRNA_hydro PF01195.14 KEY64895.1 - 4.2e-33 114.3 0.0 5.2e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase DUF1795 PF08786.6 KEY64895.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1795) Ammonium_transp PF00909.16 KEY64896.1 - 7.9e-117 390.0 24.5 9.2e-117 389.8 17.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3733 PF12534.3 KEY64897.1 - 0.0067 15.7 0.2 0.012 14.8 0.2 1.4 1 0 0 1 1 1 1 Leucine-rich repeat containing protein 8 F-box-like PF12937.2 KEY64898.1 - 2.2e-13 49.6 3.4 3.1e-13 49.1 1.1 2.4 3 0 0 3 3 3 1 F-box-like LRR_6 PF13516.1 KEY64898.1 - 1.9e-10 39.6 23.9 1.4 9.1 0.0 11.1 12 0 0 12 12 12 5 Leucine Rich repeat F-box PF00646.28 KEY64898.1 - 7.6e-07 28.6 1.2 3.3e-06 26.5 0.8 2.2 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 KEY64898.1 - 1.7e-06 27.4 9.3 0.72 9.5 0.0 6.4 4 2 3 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEY64898.1 - 3.3e-05 23.5 20.3 0.19 11.4 0.1 6.4 3 1 3 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 KEY64898.1 - 0.045 13.7 28.0 1.2 9.4 0.2 9.2 7 3 1 8 8 8 0 Leucine Rich Repeat Chalcone PF02431.10 KEY64899.1 - 1.3e-55 187.8 0.0 1.9e-55 187.3 0.0 1.2 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Glutaredoxin PF00462.19 KEY64900.1 - 3.8e-20 71.6 0.0 6.4e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 KEY64900.1 - 0.00029 20.9 0.0 0.00041 20.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEY64900.1 - 0.0013 18.7 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_9 PF14595.1 KEY64900.1 - 0.005 16.3 0.0 0.006 16.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KEY64900.1 - 0.011 15.9 0.1 0.018 15.2 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.9 KEY64900.1 - 0.013 15.6 0.0 0.021 15.0 0.0 1.5 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) THF_DHG_CYH PF00763.18 KEY64900.1 - 0.02 14.9 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain FANCI_S1-cap PF14674.1 KEY64900.1 - 0.033 14.2 0.4 0.033 14.2 0.3 1.8 2 0 0 2 2 2 0 FANCI solenoid 1 cap DSBA PF01323.15 KEY64900.1 - 0.18 11.3 0.6 1.9 8.0 0.3 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain BAG PF02179.11 KEY64901.1 - 1.5e-17 63.4 0.2 4.1e-17 62.0 0.1 1.7 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 KEY64901.1 - 0.00013 21.2 0.0 0.00025 20.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L13 PF00572.13 KEY64902.1 - 6.1e-28 97.4 0.4 9.7e-28 96.7 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L13 TPR_11 PF13414.1 KEY64903.1 - 1e-12 47.5 1.9 9.6e-08 31.5 0.6 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KEY64903.1 - 7e-10 38.0 5.2 1.9e-05 24.2 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEY64903.1 - 2.2e-08 33.3 1.8 0.0013 18.2 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEY64903.1 - 1.4e-06 28.1 1.3 0.0017 18.2 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEY64903.1 - 2.7e-06 27.8 6.6 0.005 17.4 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEY64903.1 - 3.7e-05 23.9 1.4 0.0015 18.8 1.0 2.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEY64903.1 - 0.0013 18.3 0.4 0.024 14.4 0.0 2.9 4 0 0 4 4 4 1 Tetratricopeptide repeat SPO22 PF08631.5 KEY64903.1 - 0.0029 16.7 0.0 0.21 10.6 0.0 2.1 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_14 PF13428.1 KEY64903.1 - 0.011 16.3 6.2 0.024 15.2 0.2 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 KEY64903.1 - 0.012 15.4 2.5 0.35 10.7 0.5 3.0 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEY64903.1 - 0.024 15.0 1.9 0.95 10.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KEY64903.1 - 0.11 12.5 0.0 1.2 9.2 0.0 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KEY64903.1 - 0.16 11.9 2.3 6.6 6.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEY64903.1 - 0.17 11.7 0.9 3.3 7.7 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Lyase_1 PF00206.15 KEY64905.1 - 6.4e-19 68.2 0.4 1.1e-18 67.5 0.1 1.4 2 0 0 2 2 2 1 Lyase ADSL_C PF10397.4 KEY64905.1 - 1.9e-12 46.9 0.0 5.7e-12 45.4 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Cupin_2 PF07883.6 KEY64906.1 - 0.00014 21.2 0.2 0.00027 20.3 0.1 1.5 1 0 0 1 1 1 1 Cupin domain Epimerase PF01370.16 KEY64907.1 - 1e-10 41.5 0.3 0.00022 20.7 0.2 2.4 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KEY64907.1 - 7.9e-07 28.5 0.2 1.5e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY64907.1 - 2e-05 24.7 0.6 3.8e-05 23.7 0.4 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KEY64907.1 - 3.4e-05 22.9 0.1 0.00028 19.9 0.0 2.2 2 1 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.19 KEY64907.1 - 0.00034 20.9 0.0 0.00072 19.8 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KEY64907.1 - 0.0015 17.5 0.2 0.0023 17.0 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 KEY64907.1 - 0.015 13.9 0.0 0.069 11.8 0.0 1.9 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KEY64907.1 - 0.15 10.8 0.0 0.3 9.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Aldedh PF00171.17 KEY64908.1 - 7.2e-182 604.8 0.5 8.2e-182 604.6 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KEY64908.1 - 0.019 13.7 0.0 0.039 12.6 0.0 1.4 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF2051 PF09738.4 KEY64908.1 - 0.039 13.2 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) AraC_binding PF02311.14 KEY64909.1 - 0.081 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain Adap_comp_sub PF00928.16 KEY64910.1 - 4.3e-84 281.7 0.0 5.6e-84 281.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KEY64910.1 - 4.1e-05 23.3 0.2 7.3e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Glyco_hydro_6 PF01341.12 KEY64911.1 - 5.3e-106 354.3 0.6 6.9e-106 354.0 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 KEY64911.1 - 2.8e-12 46.0 11.9 8.7e-12 44.4 8.2 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain PLDc_2 PF13091.1 KEY64913.1 - 1.2e-18 67.0 0.0 6.2e-12 45.3 0.0 3.0 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KEY64913.1 - 0.074 12.8 0.3 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 Phospholipase D Active site motif DSBA PF01323.15 KEY64914.1 - 1.1e-25 90.2 0.0 1.3e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 KEY64914.1 - 0.012 15.8 0.0 0.12 12.6 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_4 PF13462.1 KEY64914.1 - 0.016 15.2 0.0 0.063 13.2 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin Fungal_trans_2 PF11951.3 KEY64915.1 - 3.7e-26 91.6 1.5 1.2e-24 86.6 1.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF1582 PF07621.6 KEY64915.1 - 0.093 12.7 0.0 0.27 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1582) DUF1996 PF09362.5 KEY64916.1 - 8.1e-06 25.6 0.1 1.2e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TP53IP5 PF15331.1 KEY64916.1 - 0.3 10.9 4.5 0.45 10.3 3.1 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Peptidase_S46 PF10459.4 KEY64916.1 - 0.74 8.1 4.7 0.18 10.2 1.1 1.4 2 0 0 2 2 2 0 Peptidase S46 GAS PF13851.1 KEY64916.1 - 2.8 7.0 9.5 2.2 7.4 4.7 2.0 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 KEY64916.1 - 3.6 6.6 10.2 3.6 6.6 6.0 1.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Glyco_hydro_43 PF04616.9 KEY64917.1 - 1.3e-38 132.7 2.1 1.5e-38 132.5 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_43 PF04616.9 KEY64918.1 - 7.2e-39 133.5 0.5 8.9e-39 133.2 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CENP-K PF11802.3 KEY64919.1 - 0.051 12.7 4.9 0.076 12.2 3.4 1.1 1 0 0 1 1 1 0 Centromere-associated protein K D5_N PF08706.6 KEY64919.1 - 0.11 12.6 1.0 0.2 11.7 0.7 1.4 1 0 0 1 1 1 0 D5 N terminal like zf-C3H1 PF10650.4 KEY64919.1 - 0.13 11.8 0.6 0.32 10.5 0.4 1.7 1 0 0 1 1 1 0 Putative zinc-finger domain AAA_24 PF13479.1 KEY64919.1 - 0.14 11.7 1.9 0.24 10.9 1.3 1.3 1 0 0 1 1 1 0 AAA domain HSP70 PF00012.15 KEY64920.1 - 1.4e-08 33.1 0.0 2.7e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KEY64920.1 - 0.00029 19.5 0.1 0.0014 17.2 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein Dynamin_N PF00350.18 KEY64921.1 - 1.1e-61 207.5 0.1 1.2e-30 106.5 0.1 2.7 2 0 0 2 2 2 2 Dynamin family Dynamin_M PF01031.15 KEY64921.1 - 1.5e-35 122.4 0.0 6e-18 64.6 0.0 2.9 3 0 0 3 3 3 2 Dynamin central region MMR_HSR1 PF01926.18 KEY64921.1 - 1.6e-08 34.5 0.1 0.0012 18.7 0.0 4.0 2 2 0 2 2 2 2 50S ribosome-binding GTPase GED PF02212.13 KEY64921.1 - 1.4e-06 28.0 3.4 0.0011 18.7 0.1 3.6 3 1 0 3 3 3 2 Dynamin GTPase effector domain Miro PF08477.8 KEY64921.1 - 8.3e-06 26.2 0.0 0.17 12.3 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein FeoB_N PF02421.13 KEY64921.1 - 0.00078 18.7 0.2 14 4.9 0.0 4.2 4 0 0 4 4 4 0 Ferrous iron transport protein B AAA_21 PF13304.1 KEY64921.1 - 0.0041 17.1 0.0 3.8 7.3 0.0 2.8 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 KEY64921.1 - 0.0064 16.2 0.0 4.3 7.0 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KEY64921.1 - 0.0094 16.2 0.0 2.5 8.3 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_29 PF13555.1 KEY64921.1 - 0.0096 15.4 0.0 10 5.7 0.0 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KEY64921.1 - 0.023 15.0 0.0 7.2 6.8 0.0 3.3 2 1 0 2 2 2 0 AAA domain Ras PF00071.17 KEY64921.1 - 0.05 12.9 0.0 7.7 5.8 0.0 2.7 2 0 0 2 2 2 0 Ras family OTT_1508_deam PF14441.1 KEY64922.1 - 5.3e-06 26.3 0.0 9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase dCMP_cyt_deam_1 PF00383.17 KEY64922.1 - 0.066 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Dynamin_N PF00350.18 KEY64923.1 - 2.8e-28 98.8 0.1 8.1e-28 97.3 0.0 1.8 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KEY64923.1 - 3.5e-18 65.4 0.1 1.7e-16 59.9 0.0 2.4 2 0 0 2 2 2 1 Dynamin central region GED PF02212.13 KEY64923.1 - 3.3e-05 23.7 0.0 0.00025 20.8 0.0 2.5 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KEY64923.1 - 0.00037 20.4 0.0 0.0019 18.1 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEY64923.1 - 0.0011 19.4 0.0 0.0032 17.9 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein AAA_21 PF13304.1 KEY64923.1 - 0.0057 16.6 0.0 0.0098 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KEY64923.1 - 0.017 15.4 0.0 0.09 13.0 0.0 2.2 3 0 0 3 3 3 0 ABC transporter AAA_23 PF13476.1 KEY64923.1 - 0.092 13.0 0.5 0.36 11.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain ADH_zinc_N PF00107.21 KEY64924.1 - 1.4e-12 47.2 0.0 2.6e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY64924.1 - 2.3e-06 27.3 0.0 1.4e-05 24.8 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.13 KEY64925.1 - 0.00015 21.5 10.1 0.00024 20.9 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kelch_4 PF13418.1 KEY64926.1 - 3.7e-26 90.6 7.3 1.1e-10 41.0 0.0 5.6 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.1 KEY64926.1 - 3e-23 81.3 7.2 3.7e-06 26.9 0.0 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.20 KEY64926.1 - 8.1e-17 60.5 6.9 0.00017 21.0 0.0 5.6 5 2 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 KEY64926.1 - 5.9e-15 54.7 5.4 0.00085 19.3 0.0 5.6 3 1 2 5 5 5 4 Kelch motif Kelch_5 PF13854.1 KEY64926.1 - 7.3e-13 48.1 2.2 0.0033 17.3 0.1 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 KEY64926.1 - 2e-10 40.0 12.8 0.0016 18.1 0.2 4.8 3 1 1 4 4 4 4 Kelch motif Aldedh PF00171.17 KEY64927.1 - 1.4e-133 445.6 0.2 1.8e-133 445.2 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KEY64927.1 - 0.024 13.3 0.0 0.037 12.7 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Calreticulin PF00262.13 KEY64928.1 - 1.1e-159 531.0 18.3 1.4e-159 530.6 12.7 1.2 1 0 0 1 1 1 1 Calreticulin family OAD_gamma PF04277.8 KEY64928.1 - 0.19 12.1 3.3 0.28 11.5 0.5 2.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain ASC PF00858.19 KEY64929.1 - 0.1 11.2 1.8 0.12 11.0 1.2 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel DUF2457 PF10446.4 KEY64929.1 - 0.11 11.2 3.5 0.14 10.8 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Vanabin-2 PF11437.3 KEY64929.1 - 0.33 10.9 6.1 0.56 10.2 4.2 1.3 1 0 0 1 1 1 0 Vanadium-binding protein 2 Aldolase_II PF00596.16 KEY64930.1 - 1.7e-37 128.7 0.0 2.3e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Sec20 PF03908.8 KEY64931.1 - 1.1e-12 47.4 0.2 3.3e-12 45.9 0.0 1.9 2 0 0 2 2 2 1 Sec20 STAT_alpha PF01017.15 KEY64931.1 - 0.32 10.6 5.4 1.9 8.1 0.4 3.2 2 2 1 3 3 3 0 STAT protein, all-alpha domain MRP_L53 PF10780.4 KEY64932.1 - 5.8e-20 71.0 0.6 8.5e-20 70.4 0.4 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Ecotin PF03974.8 KEY64932.1 - 0.032 13.9 0.0 0.039 13.6 0.0 1.1 1 0 0 1 1 1 0 Ecotin Pyrophosphatase PF00719.14 KEY64933.1 - 5.4e-52 175.3 0.1 7.3e-52 174.9 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF566 PF04484.7 KEY64933.1 - 2.3 7.6 7.2 3 7.2 5.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Pil1 PF13805.1 KEY64934.1 - 7.5e-104 346.6 2.8 1.1e-103 346.1 1.9 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Ribophorin_I PF04597.9 KEY64935.1 - 6.3e-142 473.0 0.0 7.2e-142 472.8 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I Hexokinase_2 PF03727.11 KEY64936.1 - 4.4e-88 294.5 0.0 5.9e-88 294.1 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KEY64936.1 - 1.3e-74 249.9 0.0 7.3e-74 247.5 0.0 1.9 2 0 0 2 2 2 1 Hexokinase Ank_2 PF12796.2 KEY64937.1 - 0.0031 17.8 0.0 0.019 15.2 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) VTC PF09359.5 KEY64938.1 - 1.8e-96 322.5 0.0 2.6e-96 321.9 0.0 1.3 1 0 0 1 1 1 1 VTC domain Cys_Met_Meta_PP PF01053.15 KEY64938.1 - 5.2e-25 87.5 0.0 7.6e-25 86.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SPX PF03105.14 KEY64938.1 - 7e-21 75.2 4.1 1e-10 41.9 0.4 3.5 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 KEY64938.1 - 8e-11 42.0 2.0 2.3e-10 40.5 1.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Aminotran_1_2 PF00155.16 KEY64938.1 - 0.00015 20.8 0.0 0.0003 19.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II MCM PF00493.18 KEY64939.1 - 7.9e-140 465.3 0.1 1e-139 464.9 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KEY64939.1 - 7.2e-24 84.5 0.1 5.1e-23 81.8 0.0 2.4 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.9 KEY64939.1 - 2.1e-05 24.2 0.1 0.00025 20.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KEY64939.1 - 7.4e-05 21.9 0.0 0.00064 18.9 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KEY64939.1 - 0.0037 16.8 0.0 0.013 15.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.1 KEY64939.1 - 0.0079 14.9 0.9 0.013 14.1 0.7 1.2 1 0 0 1 1 1 1 AAA domain Clat_adaptor_s PF01217.15 KEY64940.1 - 4.3e-15 55.6 0.8 2.5e-14 53.1 0.6 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Sua5_yciO_yrdC PF01300.13 KEY64941.1 - 3.9e-54 182.6 0.0 5.8e-54 182.0 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 KEY64941.1 - 2.3e-25 89.1 0.0 4.4e-25 88.1 0.0 1.5 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding COG4 PF08318.7 KEY64942.1 - 3.3e-94 315.3 0.0 4.6e-94 314.8 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein E1-E2_ATPase PF00122.15 KEY64942.1 - 1.7e-72 243.2 0.2 3.5e-72 242.1 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEY64942.1 - 5.8e-40 136.7 0.5 1.2e-39 135.6 0.3 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEY64942.1 - 2.1e-29 103.4 0.0 1.9e-28 100.3 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEY64942.1 - 4e-19 67.8 0.0 1.1e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KEY64942.1 - 2.2e-14 54.0 0.0 7.2e-14 52.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEY64942.1 - 3.2e-14 52.6 0.0 7.8e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEY64942.1 - 9e-05 22.1 0.5 0.00044 19.9 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.8 KEY64943.1 - 1.4e-31 108.7 0.0 2.6e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KEY64943.1 - 2.6e-08 32.9 0.0 7e-08 31.5 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KEY64943.1 - 0.07 12.7 0.3 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 ScpA/B protein TBCA PF02970.11 KEY64944.1 - 7.6e-15 54.7 11.2 2.7e-14 53.0 7.0 2.0 1 1 1 2 2 2 1 Tubulin binding cofactor A RRF_GI PF12614.3 KEY64944.1 - 0.07 12.9 2.6 0.094 12.5 1.8 1.2 1 0 0 1 1 1 0 Ribosome recycling factor SRP19 PF01922.12 KEY64944.1 - 0.11 13.0 0.5 0.25 11.9 0.1 1.6 2 0 0 2 2 2 0 SRP19 protein DUF4407 PF14362.1 KEY64944.1 - 0.3 10.0 10.2 0.34 9.8 7.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin PF00804.20 KEY64944.1 - 0.43 10.7 4.3 0.56 10.4 3.0 1.3 1 0 0 1 1 1 0 Syntaxin DUF4164 PF13747.1 KEY64944.1 - 0.45 10.6 6.0 0.19 11.8 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) IncA PF04156.9 KEY64944.1 - 1.5 8.4 7.2 1.8 8.1 5.0 1.2 1 0 0 1 1 1 0 IncA protein eIF3_N PF09440.5 KEY64944.1 - 1.6 8.9 5.4 1.6 8.9 0.6 2.1 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain SlyX PF04102.7 KEY64944.1 - 5.5 7.4 6.6 1.8 8.9 0.6 2.4 1 1 1 2 2 2 0 SlyX THOC7 PF05615.8 KEY64945.1 - 1.1e-36 126.1 5.2 1.1e-36 126.1 3.6 1.9 1 1 1 2 2 2 1 Tho complex subunit 7 FUSC PF04632.7 KEY64945.1 - 0.17 10.2 5.6 0.23 9.8 3.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-C4H2 PF10146.4 KEY64945.1 - 0.26 11.2 7.3 0.41 10.6 2.8 2.1 1 1 1 2 2 2 0 Zinc finger-containing protein RTBV_P46 PF06216.6 KEY64945.1 - 0.77 8.5 7.3 1.8 7.3 0.4 2.1 1 1 0 2 2 2 0 Rice tungro bacilliform virus P46 protein zf-CCCH PF00642.19 KEY64946.1 - 8.8e-05 22.0 0.1 8.8e-05 22.0 0.1 4.5 3 1 1 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRV_FeS PF05484.6 KEY64946.1 - 0.04 13.4 0.6 0.04 13.4 0.4 2.7 2 1 1 3 3 3 0 LRV protein FeS4 cluster Sel1 PF08238.7 KEY64947.1 - 4.5e-05 23.9 0.1 0.067 13.8 0.1 2.6 2 0 0 2 2 2 2 Sel1 repeat bZIP_1 PF00170.16 KEY64948.1 - 2.1e-11 43.6 7.4 2.1e-11 43.6 5.1 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 KEY64948.1 - 6.1e-08 32.8 7.7 1.8e-07 31.3 5.4 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 KEY64948.1 - 2.2e-05 24.1 6.1 2.2e-05 24.1 4.2 2.3 2 0 0 2 2 2 1 Basic region leucine zipper Endotoxin_N PF03945.9 KEY64948.1 - 0.03 13.6 2.3 0.066 12.6 1.6 1.5 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain V_ATPase_I PF01496.14 KEY64948.1 - 7.8 4.2 7.7 3 5.6 3.3 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family SUN PF03856.8 KEY64949.1 - 5.7e-88 294.4 11.3 7.3e-88 294.0 7.9 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF605 PF04652.11 KEY64949.1 - 4.8 6.4 11.0 6.5 6.0 7.6 1.2 1 0 0 1 1 1 0 Vta1 like MFS_1 PF07690.11 KEY64950.1 - 8.2e-16 57.6 17.8 1.8e-15 56.5 12.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF349 PF03993.7 KEY64950.1 - 0.12 12.5 0.3 0.12 12.5 0.2 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Hist_deacetyl PF00850.14 KEY64951.1 - 2.1e-79 267.0 0.0 7.5e-79 265.2 0.0 1.8 1 1 1 2 2 2 1 Histone deacetylase domain ING PF12998.2 KEY64952.1 - 3.9e-22 78.5 5.5 6.8e-22 77.7 3.8 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KEY64952.1 - 2.8e-08 33.3 9.3 5.4e-08 32.4 6.4 1.5 1 0 0 1 1 1 1 PHD-finger DUF2552 PF10827.3 KEY64952.1 - 0.064 13.1 0.1 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2552) PAT1 PF09770.4 KEY64952.1 - 0.16 10.2 21.2 0.24 9.6 14.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-PARP PF00645.13 KEY64952.1 - 1.8 8.8 4.4 11 6.3 0.2 2.3 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region ADSL_C PF10397.4 KEY64953.1 - 0.0094 15.9 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Methyltransf_16 PF10294.4 KEY64953.1 - 0.11 11.9 0.0 0.67 9.3 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Complex1_LYR PF05347.10 KEY64954.1 - 7.2e-07 28.9 0.1 1.2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KEY64954.1 - 8.2e-05 22.7 0.3 0.00012 22.1 0.2 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KEY64954.1 - 0.00043 20.7 0.4 0.00082 19.8 0.3 1.5 1 1 0 1 1 1 1 Complex1_LYR-like PMT_C PF11647.3 KEY64954.1 - 0.023 14.3 0.5 6.4 6.4 0.0 2.2 2 0 0 2 2 2 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 HA2 PF04408.18 KEY64955.1 - 4.2e-16 58.8 0.0 1e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KEY64955.1 - 2.2e-15 56.4 0.1 5.3e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KEY64955.1 - 4.4e-12 45.6 0.0 1.1e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEY64955.1 - 3.9e-07 29.7 0.0 2e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEY64955.1 - 0.00063 19.8 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KEY64955.1 - 0.0082 15.6 0.0 0.022 14.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KEY64955.1 - 0.071 13.4 0.1 0.34 11.2 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 KEY64955.1 - 0.091 12.7 2.0 0.18 11.7 0.1 2.4 3 1 0 3 3 3 0 AAA ATPase domain SNARE PF05739.14 KEY64956.1 - 0.00013 21.5 6.7 0.00013 21.5 4.7 2.3 2 0 0 2 2 2 1 SNARE domain GTP_EFTU PF00009.22 KEY64957.1 - 8.8e-10 38.3 0.0 2.8e-09 36.6 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Rab5ip PF07019.7 KEY64958.1 - 3.6e-20 71.8 7.9 4.4e-20 71.6 5.5 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) PIG-P PF08510.7 KEY64958.1 - 3.4 7.3 5.1 2.3 7.8 2.6 1.5 1 1 0 1 1 1 0 PIG-P URO-D PF01208.12 KEY64959.1 - 1.8e-122 408.5 0.0 2e-122 408.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF3602 PF12223.3 KEY64960.1 - 4.5e-16 58.9 10.8 4.4e-14 52.6 2.5 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) Velvet PF11754.3 KEY64961.1 - 7e-70 234.7 0.0 1.5e-69 233.6 0.0 1.5 2 0 0 2 2 2 1 Velvet factor HisG PF01634.13 KEY64962.1 - 8.6e-43 145.7 0.2 4.5e-31 107.6 0.0 2.3 2 0 0 2 2 2 2 ATP phosphoribosyltransferase HisG_C PF08029.6 KEY64962.1 - 1.8e-27 95.0 0.1 3.2e-27 94.2 0.1 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain Trs65 PF12735.2 KEY64964.1 - 0.11 11.7 2.2 0.14 11.4 1.5 1.0 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 SR-25 PF10500.4 KEY64964.1 - 0.8 9.1 8.3 0.92 8.9 5.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ion_trans PF00520.26 KEY64965.1 - 6.2e-102 338.9 79.0 6.5e-35 120.2 2.1 5.2 4 1 0 4 4 4 4 Ion transport protein EF-hand_1 PF00036.27 KEY64965.1 - 0.053 12.8 0.0 0.19 11.1 0.0 2.0 1 0 0 1 1 1 0 EF hand JSRP PF15312.1 KEY64965.1 - 0.095 12.6 0.0 0.27 11.2 0.0 1.8 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein PHD PF00628.24 KEY64966.1 - 3e-08 33.2 7.9 6e-08 32.2 5.5 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KEY64966.1 - 0.023 14.0 4.7 0.045 13.0 3.2 1.5 1 0 0 1 1 1 0 PHD-finger AAA_23 PF13476.1 KEY64966.1 - 1.6 9.0 8.5 3.6 7.8 5.9 1.6 1 0 0 1 1 1 0 AAA domain HMG_box PF00505.14 KEY64967.1 - 4e-16 59.0 0.1 6.6e-15 55.1 0.1 2.7 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KEY64967.1 - 3.9e-05 23.9 0.1 8.3e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 KEY64967.1 - 0.03 13.6 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 MMgT PF10270.4 KEY64968.1 - 3.2e-30 104.6 0.0 3.6e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter N_methyl_3 PF13633.1 KEY64968.1 - 5.2 7.1 7.0 0.21 11.5 0.6 1.8 2 0 0 2 2 2 0 Prokaryotic N-terminal methylation site MutS_V PF00488.16 KEY64969.1 - 5.3e-59 199.4 0.0 9.3e-59 198.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KEY64969.1 - 8.5e-17 61.6 0.8 1.7e-16 60.6 0.0 2.0 2 0 0 2 2 2 1 MutS domain III CRAL_TRIO_N PF03765.10 KEY64969.1 - 0.013 15.6 0.0 0.032 14.3 0.0 1.7 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain AAA_14 PF13173.1 KEY64969.1 - 0.087 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Adenylsucc_synt PF00709.16 KEY64972.1 - 2.9e-153 510.4 0.0 3.4e-153 510.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase KRAB PF01352.22 KEY64973.1 - 0.024 14.0 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 KRAB box WD40 PF00400.27 KEY64974.1 - 4.2e-13 48.6 1.9 0.88 9.5 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat UAA PF08449.6 KEY64975.1 - 2.6e-92 309.0 3.7 3.2e-92 308.6 2.5 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 KEY64975.1 - 0.0005 19.2 0.1 0.0005 19.2 0.1 2.2 3 0 0 3 3 3 1 Nucleotide-sugar transporter TPT PF03151.11 KEY64975.1 - 0.0018 17.9 4.6 0.0018 17.9 3.2 2.5 2 2 0 2 2 2 1 Triose-phosphate Transporter family UPF0546 PF10639.4 KEY64975.1 - 0.05 13.4 4.2 0.24 11.2 0.4 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 Cyt_c_ox_IV PF12270.3 KEY64975.1 - 0.19 11.4 2.8 0.32 10.7 0.0 2.6 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV EamA PF00892.15 KEY64975.1 - 0.6 10.1 28.2 1.3 9.1 2.4 3.6 2 1 2 4 4 4 0 EamA-like transporter family EmrE PF13536.1 KEY64975.1 - 0.62 10.2 23.0 0.16 12.1 3.1 3.5 3 1 1 4 4 4 0 Multidrug resistance efflux transporter A_deaminase PF00962.17 KEY64976.1 - 4.5e-113 377.5 0.2 6.1e-113 377.0 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase SHD1 PF03983.7 KEY64977.1 - 4.7e-36 122.2 0.1 8.3e-36 121.4 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 KEY64977.1 - 5e-36 121.8 7.2 1.8e-13 49.5 0.1 4.3 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 KEY64977.1 - 6.6e-34 115.2 7.8 4.3e-12 45.4 0.2 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 KEY64977.1 - 8.4e-28 95.6 0.2 7.2e-08 31.8 0.0 5.2 5 0 0 5 5 5 4 Variant SH3 domain DUF1720 PF08226.6 KEY64977.1 - 1.7e-06 28.0 20.3 1.7e-06 28.0 14.1 6.2 1 1 2 3 3 3 1 Domain of unknown function (DUF1720) SH3_3 PF08239.6 KEY64977.1 - 7.7e-05 22.8 6.1 0.037 14.1 0.7 3.5 3 0 0 3 3 3 2 Bacterial SH3 domain TRAM_LAG1_CLN8 PF03798.11 KEY64978.1 - 1.1e-47 162.1 14.8 1.7e-47 161.5 10.2 1.3 1 0 0 1 1 1 1 TLC domain Cation_efflux PF01545.16 KEY64978.1 - 2.2 7.2 7.7 8.9 5.2 5.4 1.9 1 1 0 1 1 1 0 Cation efflux family Dor1 PF04124.7 KEY64979.1 - 1.1e-48 165.4 0.3 1.8e-41 141.7 0.2 2.7 1 1 1 2 2 2 2 Dor1-like family TT_ORF2a PF08197.6 KEY64979.1 - 0.083 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 pORF2a truncated protein Prefoldin_2 PF01920.15 KEY64981.1 - 2.4e-15 56.1 4.6 3.1e-15 55.8 3.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF4265 PF14085.1 KEY64981.1 - 0.066 12.9 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) FlxA PF14282.1 KEY64981.1 - 0.63 10.0 7.9 0.67 9.9 0.6 2.2 2 0 0 2 2 2 0 FlxA-like protein Thiolase_C PF02803.13 KEY64982.1 - 1.7e-12 46.8 0.2 5.9e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KEY64982.1 - 5.6e-07 29.1 0.1 2.4e-05 23.8 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 KEY64982.1 - 0.00017 20.6 0.2 0.00063 18.8 0.0 2.0 3 0 0 3 3 3 1 Thiolase, N-terminal domain Ketoacyl-synt_C PF02801.17 KEY64982.1 - 0.00039 20.2 0.2 0.012 15.4 0.0 2.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 KEY64982.1 - 0.0048 16.4 0.1 0.018 14.5 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.6 KEY64982.1 - 0.0075 14.7 0.1 0.042 12.2 0.1 2.0 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) DUF3208 PF11482.3 KEY64982.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) HMA PF00403.21 KEY64983.1 - 3e-14 52.9 0.5 4.4e-14 52.3 0.4 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain Actin PF00022.14 KEY64984.1 - 8.3e-88 294.4 0.0 1.8e-87 293.3 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KEY64984.1 - 0.039 12.5 0.0 2.8 6.4 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.13 KEY64985.1 - 2.1e-33 115.3 4.4 1.2e-18 66.9 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Tfb4 PF03850.9 KEY64986.1 - 5.4e-95 317.8 0.0 6.2e-95 317.5 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 KEY64986.1 - 7.5e-05 22.9 1.4 0.00011 22.3 1.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain DUF2668 PF10873.3 KEY64986.1 - 0.0091 16.1 0.4 0.061 13.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2668) zf-C2HC5 PF06221.8 KEY64986.1 - 0.026 14.2 4.9 0.047 13.4 3.4 1.4 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type IFRD PF05004.8 KEY64986.1 - 0.059 12.4 0.1 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) UNC45-central PF11701.3 KEY64987.1 - 2.1e-44 150.9 0.0 7.3e-43 145.9 0.0 2.8 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 KEY64987.1 - 0.0012 19.0 15.2 1.6 9.0 0.6 5.5 4 1 2 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 KEY64987.1 - 3.9 8.0 15.9 1.1 9.8 0.3 5.0 5 0 0 5 5 5 0 HEAT-like repeat tRNA_U5-meth_tr PF05958.6 KEY64988.1 - 1.6e-14 53.3 0.0 2.3e-13 49.5 0.0 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 KEY64988.1 - 2.3e-08 33.7 0.0 4.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 KEY64988.1 - 4.2e-08 32.9 0.0 7.4e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 KEY64988.1 - 4e-05 24.1 0.1 0.00011 22.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY64988.1 - 7.1e-05 22.8 0.1 0.00031 20.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain TRAM PF01938.15 KEY64988.1 - 0.00091 18.9 0.0 0.0029 17.3 0.0 1.8 1 0 0 1 1 1 1 TRAM domain Cons_hypoth95 PF03602.10 KEY64988.1 - 0.0036 16.7 0.0 0.0079 15.6 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.1 KEY64988.1 - 0.0091 16.3 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY64988.1 - 0.015 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.7 KEY64988.1 - 0.023 15.2 0.0 0.076 13.5 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain G_glu_transpept PF01019.16 KEY64989.1 - 9.3e-15 54.0 0.0 5.2e-13 48.3 0.0 2.0 2 0 0 2 2 2 2 Gamma-glutamyltranspeptidase Glycos_transf_1 PF00534.15 KEY64990.1 - 4.5e-20 71.7 0.0 7.1e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KEY64990.1 - 2.9e-09 37.1 0.1 1.3e-08 35.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 60KD_IMP PF02096.15 KEY64991.1 - 1.8e-15 57.1 0.0 2.4e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein DUF3325 PF11804.3 KEY64991.1 - 0.57 10.1 5.5 0.2 11.6 1.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3325) Syntaxin_2 PF14523.1 KEY64992.1 - 2.2e-25 88.6 3.5 2.2e-25 88.6 2.4 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 KEY64992.1 - 2.7e-14 52.6 7.1 4.8e-14 51.7 4.2 2.1 2 0 0 2 2 2 1 SNARE domain Synaptobrevin PF00957.16 KEY64992.1 - 0.0034 16.9 0.7 0.01 15.4 0.5 1.8 1 0 0 1 1 1 1 Synaptobrevin DUF912 PF06024.7 KEY64992.1 - 0.091 12.8 0.4 0.28 11.2 0.3 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) T2SF PF00482.18 KEY64992.1 - 0.18 11.7 1.0 0.46 10.4 0.2 2.1 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF4635 PF15466.1 KEY64992.1 - 0.22 10.8 3.7 5.9 6.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4635) DUF1664 PF07889.7 KEY64992.1 - 0.25 11.1 7.4 3.3 7.5 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.4 KEY64992.1 - 0.35 10.8 9.0 0.11 12.4 1.6 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein UPF0184 PF03670.8 KEY64992.1 - 0.43 10.7 0.1 0.43 10.7 0.1 2.8 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0184) DUF883 PF05957.8 KEY64992.1 - 1.5 9.2 10.7 1.7 9.1 0.1 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Ndc1_Nup PF09531.5 KEY64993.1 - 7.9e-130 434.1 0.1 1e-129 433.7 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup UPF0122 PF04297.9 KEY64993.1 - 0.02 14.9 0.4 0.37 10.8 0.0 2.4 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like NICE-3 PF07406.6 KEY64994.1 - 0.0011 18.4 0.1 0.04 13.4 0.0 2.2 2 0 0 2 2 2 1 NICE-3 protein DUF4393 PF14337.1 KEY64994.1 - 0.038 13.4 0.0 0.79 9.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4393) DUF4129 PF13559.1 KEY64994.1 - 0.086 12.8 1.0 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) Birna_RdRp PF04197.7 KEY64995.1 - 0.5 8.3 11.6 0.61 8.0 8.0 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) Rpn3_C PF08375.6 KEY64995.1 - 4.1 7.8 0.0 4.1 7.8 0.0 3.7 3 1 0 3 3 3 0 Proteasome regulatory subunit C-terminal Herpes_DNAp_acc PF04929.7 KEY64995.1 - 8.5 5.2 12.4 11 4.8 8.6 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor HSF_DNA-bind PF00447.12 KEY64996.1 - 2.1e-34 117.8 0.6 3.1e-34 117.2 0.4 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Hexapep_2 PF14602.1 KEY64997.1 - 1.2e-12 47.1 19.0 2.1e-06 27.2 1.7 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 KEY64997.1 - 1.5e-12 46.3 20.2 2e-07 30.2 2.2 3.3 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 KEY64997.1 - 5.5e-11 42.3 0.1 1.2e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.13 KEY64997.1 - 0.002 17.9 6.1 0.0043 16.9 4.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_11 PF13720.1 KEY64997.1 - 0.022 14.9 0.1 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 PPR_2 PF13041.1 KEY64998.1 - 7.7e-12 45.0 0.1 3.7e-05 23.6 0.0 5.7 3 2 4 7 7 7 4 PPR repeat family PPR_3 PF13812.1 KEY64998.1 - 9.1e-07 28.6 0.4 0.74 10.2 0.0 4.8 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.15 KEY64998.1 - 0.17 11.9 0.0 26 5.0 0.0 3.7 3 0 0 3 3 3 0 PPR repeat PPR_1 PF12854.2 KEY64998.1 - 0.22 11.0 0.0 14 5.2 0.0 3.7 4 0 0 4 4 4 0 PPR repeat cwf18 PF08315.7 KEY64999.1 - 2.1e-44 151.0 5.4 2.1e-44 151.0 3.7 1.7 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor HK97-gp10_like PF04883.7 KEY64999.1 - 2.3 9.2 5.2 27 5.7 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component zf-CCHC_3 PF13917.1 KEY65000.1 - 1.3e-10 40.8 0.5 3.5e-10 39.4 0.4 1.7 1 0 0 1 1 1 1 Zinc knuckle ANAPC15 PF15243.1 KEY65000.1 - 0.045 13.8 0.5 0.045 13.8 0.4 2.5 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 15 SUZ PF12752.2 KEY65001.1 - 7.9e-12 45.5 2.0 7.9e-12 45.5 1.4 2.6 2 0 0 2 2 2 1 SUZ domain R3H PF01424.17 KEY65001.1 - 7.9e-07 28.6 0.0 1.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 R3H domain JAB PF01398.16 KEY65002.1 - 8.3e-16 57.7 0.0 1.4e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KEY65002.1 - 2.7e-14 53.2 0.1 5.3e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF1253 PF06862.7 KEY65003.1 - 1.7e-164 547.4 0.0 2.2e-164 547.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DEAD PF00270.24 KEY65003.1 - 0.0063 16.0 0.0 0.19 11.1 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_L17 PF01196.14 KEY65004.1 - 7.9e-28 96.8 1.9 1.7e-27 95.7 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L17 ATP-synt_B PF00430.13 KEY65004.1 - 0.88 9.3 6.1 0.66 9.7 0.9 2.2 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DUF883 PF05957.8 KEY65005.1 - 0.02 15.3 15.4 1.6 9.1 5.6 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 KEY65005.1 - 0.4 10.1 7.0 5.4 6.4 1.4 2.3 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain ALAD PF00490.16 KEY65007.1 - 1.9e-118 395.0 0.0 2.2e-118 394.8 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Acyl_transf_3 PF01757.17 KEY65008.1 - 8.3e-44 149.7 30.8 1.2e-43 149.2 21.3 1.3 1 0 0 1 1 1 1 Acyltransferase family Amidohydro_3 PF07969.6 KEY65009.1 - 7.9e-63 213.0 2.5 9.8e-63 212.7 1.7 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 KEY65009.1 - 0.0045 16.6 0.0 0.038 13.6 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 KEY65009.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 Amidohydrolase PTS-HPr PF00381.14 KEY65009.1 - 0.13 12.1 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 PTS HPr component phosphorylation site SR-25 PF10500.4 KEY65013.1 - 0.25 10.8 15.3 0.21 11.0 10.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RNA_polI_A34 PF08208.6 KEY65013.1 - 0.29 10.7 16.4 0.23 11.0 11.4 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3464 PF11947.3 KEY65013.1 - 1.5 8.3 4.5 1.2 8.5 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) BLVR PF06375.6 KEY65013.1 - 3.2 7.5 22.5 4.1 7.2 15.6 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Protocadherin PF08374.6 KEY65013.1 - 4.4 6.8 8.4 4.3 6.9 5.8 1.2 1 0 0 1 1 1 0 Protocadherin NPR3 PF03666.8 KEY65013.1 - 5.6 5.3 9.3 5.6 5.3 6.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1279 PF06916.8 KEY65014.1 - 7.7e-27 93.4 0.0 1.9e-26 92.1 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) FA_desaturase PF00487.19 KEY65014.1 - 0.042 13.2 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Fatty acid desaturase AAA_10 PF12846.2 KEY65015.1 - 0.049 13.0 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain PNGaseA PF12222.3 KEY65016.1 - 2.8e-86 290.0 0.0 4e-86 289.5 0.0 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Inhibitor_I53 PF11714.3 KEY65017.1 - 0.12 12.3 0.5 0.18 11.8 0.4 1.2 1 0 0 1 1 1 0 Thrombin inhibitor Madanin MARVEL PF01284.18 KEY65018.1 - 4.5e-25 88.1 14.0 5.5e-25 87.8 9.7 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF3974 PF13120.1 KEY65019.1 - 0.085 12.6 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) eIF-5_eIF-2B PF01873.12 KEY65020.1 - 6e-45 151.9 1.1 9.4e-45 151.3 0.7 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Fez1 PF06818.10 KEY65020.1 - 0.031 14.3 0.9 0.051 13.5 0.6 1.2 1 0 0 1 1 1 0 Fez1 Lar_restr_allev PF14354.1 KEY65020.1 - 0.05 13.8 0.2 0.16 12.3 0.1 1.9 1 0 0 1 1 1 0 Restriction alleviation protein Lar Ykof PF07615.6 KEY65020.1 - 0.13 12.4 0.0 0.45 10.7 0.0 1.8 2 0 0 2 2 2 0 YKOF-related Family Rap1-DNA-bind PF09197.5 KEY65020.1 - 0.14 12.7 1.1 0.75 10.3 0.1 2.5 2 1 0 2 2 2 0 Rap1, DNA-binding Arc_trans_TRASH PF08394.5 KEY65020.1 - 1.1 9.4 7.7 1 9.5 0.2 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain zf-HYPF PF07503.7 KEY65020.1 - 5.3 6.5 7.2 3 7.3 2.8 2.3 2 1 1 3 3 3 0 HypF finger Nucleoporin_N PF08801.6 KEY65021.1 - 1.2e-75 254.8 0.0 1.6e-75 254.4 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.9 KEY65021.1 - 2.3e-72 244.3 14.5 3.2e-72 243.9 10.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal AFG1_ATPase PF03969.11 KEY65022.1 - 1.3e-50 172.2 0.0 1.2e-25 90.1 0.0 5.0 4 1 1 5 5 5 5 AFG1-like ATPase AAA_5 PF07728.9 KEY65022.1 - 5.6e-05 22.9 0.0 0.00016 21.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEY65022.1 - 0.00081 19.4 0.3 0.04 13.9 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KEY65022.1 - 0.0016 18.6 0.0 0.0074 16.4 0.0 2.1 2 1 1 3 3 3 1 AAA domain Bac_DnaA PF00308.13 KEY65022.1 - 0.004 16.8 0.0 3.1 7.3 0.0 2.4 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_14 PF13173.1 KEY65022.1 - 0.02 14.7 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KEY65022.1 - 0.021 15.0 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 KEY65022.1 - 0.067 12.1 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.1 KEY65022.1 - 0.091 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 KEY65022.1 - 0.091 12.4 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Acyl_transf_1 PF00698.16 KEY65023.1 - 2.7e-19 69.6 0.0 1.4e-14 54.2 0.0 2.2 2 0 0 2 2 2 2 Acyl transferase domain Sedlin_N PF04628.8 KEY65023.1 - 2.5e-15 56.4 0.0 4.3e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Adap_comp_sub PF00928.16 KEY65024.1 - 7e-61 205.6 0.0 4.3e-60 203.0 0.0 1.9 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KEY65024.1 - 3.7e-05 23.4 0.0 5.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4536 PF15055.1 KEY65025.1 - 0.27 11.3 3.7 0.39 10.8 2.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4536) ECR1_N PF14382.1 KEY65026.1 - 1.2e-08 34.1 0.0 3.2e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 KEY65026.1 - 0.00022 21.1 0.2 0.0011 18.8 0.1 2.2 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 Aldedh PF00171.17 KEY65027.1 - 4.7e-75 252.6 0.0 5.8e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MRP-S28 PF10213.4 KEY65028.1 - 3.4e-44 149.9 0.1 4.8e-43 146.2 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein RHH_1 PF01402.16 KEY65028.1 - 0.052 13.4 0.0 2.8 7.9 0.0 3.3 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Imm46 PF15585.1 KEY65028.1 - 0.063 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 46 Glyco_tran_28_C PF04101.11 KEY65029.1 - 1.3e-19 70.4 0.0 1.3e-18 67.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KEY65029.1 - 8.9e-05 21.8 0.0 0.00011 21.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 PPARgamma_N PF12577.3 KEY65029.1 - 0.036 14.3 0.0 0.062 13.6 0.0 1.4 1 0 0 1 1 1 0 PPAR gamma N-terminal region UDPGT PF00201.13 KEY65029.1 - 0.12 10.8 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase WD40 PF00400.27 KEY65030.1 - 4.6e-52 172.1 16.3 1.1e-09 37.7 0.1 11.1 11 0 0 11 11 11 9 WD domain, G-beta repeat PD40 PF07676.7 KEY65030.1 - 0.00071 19.1 0.2 10 5.9 0.0 4.6 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 KEY65030.1 - 0.011 15.4 0.3 0.85 9.2 0.0 3.1 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A NHL PF01436.16 KEY65030.1 - 0.17 11.8 0.5 1.7 8.7 0.1 3.1 2 0 0 2 2 2 0 NHL repeat DUF3639 PF12341.3 KEY65030.1 - 2.1 8.4 5.5 0.73 9.8 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3639) DUF1487 PF07368.6 KEY65031.1 - 0.16 11.1 0.2 0.21 10.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) CFEM PF05730.6 KEY65031.1 - 2.1 8.2 12.5 5.2 6.9 8.5 2.0 1 1 0 1 1 1 0 CFEM domain p450 PF00067.17 KEY65034.1 - 3.1e-68 230.3 0.0 3.8e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF202 PF02656.10 KEY65036.1 - 4.6e-13 49.1 4.8 4.6e-13 49.1 3.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2207 PF09972.4 KEY65036.1 - 0.073 11.6 0.2 0.089 11.3 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Tctex-1 PF03645.8 KEY65037.1 - 2.6e-21 75.3 0.0 3.2e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF605 PF04652.11 KEY65038.1 - 0.053 12.9 1.7 0.062 12.7 1.2 1.1 1 0 0 1 1 1 0 Vta1 like Histone_HNS PF00816.16 KEY65038.1 - 0.099 13.1 0.3 0.49 10.9 0.1 2.1 2 0 0 2 2 2 0 H-NS histone family Fringe PF02434.11 KEY65039.1 - 0.021 14.0 0.8 0.29 10.3 0.5 2.1 1 1 0 1 1 1 0 Fringe-like Ceramidase_alk PF04734.8 KEY65040.1 - 5.5e-277 920.1 0.0 6.3e-277 919.9 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase A2M_N PF01835.14 KEY65040.1 - 0.085 13.1 0.2 0.25 11.6 0.1 1.8 2 0 0 2 2 2 0 MG2 domain bZIP_1 PF00170.16 KEY65041.1 - 0.17 11.8 10.5 0.096 12.6 4.9 2.0 2 0 0 2 2 2 0 bZIP transcription factor DUF3435 PF11917.3 KEY65041.1 - 7.7 5.1 9.2 19 3.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) PAT1 PF09770.4 KEY65041.1 - 8.5 4.4 8.8 9.7 4.2 6.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Metallophos PF00149.23 KEY65043.1 - 1.2e-35 122.7 0.6 1.9e-28 99.2 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase GRP PF07172.6 KEY65045.1 - 0.33 11.4 14.3 0.88 10.0 9.9 1.7 1 0 0 1 1 1 0 Glycine rich protein family Cyclin_N PF00134.18 KEY65047.1 - 5.3e-07 29.2 0.0 5.5e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain CPSase_L_D2 PF02786.12 KEY65048.1 - 5.6e-113 375.4 0.2 5.6e-84 280.6 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 KEY65048.1 - 5.2e-47 159.7 0.0 1.2e-46 158.6 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 KEY65048.1 - 6.8e-45 151.7 0.0 1.5e-44 150.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 KEY65048.1 - 2.4e-42 143.9 0.0 5.1e-42 142.8 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 KEY65048.1 - 1.1e-41 141.4 0.0 2.6e-41 140.2 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 KEY65048.1 - 4.7e-41 139.3 0.0 4.3e-20 71.8 0.0 3.0 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KEY65048.1 - 1.3e-34 119.5 0.2 1.3e-21 77.1 0.1 2.7 3 0 0 3 3 3 2 ATP-grasp domain OTCace PF00185.19 KEY65048.1 - 1.9e-34 118.8 0.0 4.6e-34 117.5 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.17 KEY65048.1 - 8.3e-24 83.3 0.0 4.2e-23 81.1 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain ATPgrasp_Ter PF15632.1 KEY65048.1 - 1.9e-22 79.4 0.1 1.8e-12 46.6 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KEY65048.1 - 1.3e-15 57.3 0.5 6.5e-07 28.9 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KEY65048.1 - 1e-14 54.2 0.1 3.6e-06 26.4 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 KEY65048.1 - 7.4e-07 28.8 0.1 2.5e-05 23.8 0.0 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 KEY65048.1 - 3.5e-06 26.9 0.4 0.056 13.2 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.19 KEY65048.1 - 0.0019 17.6 0.0 0.0045 16.4 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family GARS_A PF01071.14 KEY65048.1 - 0.0039 16.7 0.1 3.2 7.2 0.0 3.2 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain PNPOx_C PF10590.4 KEY65049.1 - 3.3e-18 64.8 3.7 6.6e-18 63.9 2.5 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 KEY65049.1 - 4.1e-15 55.5 0.0 7.6e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Aminotran_1_2 PF00155.16 KEY65050.1 - 2.4e-62 210.9 0.0 2.9e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KEY65050.1 - 0.099 10.9 0.0 0.23 9.6 0.0 1.6 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.8 KEY65050.1 - 0.18 10.4 0.0 0.3 9.7 0.0 1.3 1 0 0 1 1 1 0 Allinase Glyco_hydro_76 PF03663.9 KEY65051.1 - 1.6e-125 419.3 2.5 1.9e-125 419.1 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KEY65051.1 - 0.034 13.1 4.5 2.4 7.1 0.3 3.0 2 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 Ald_Xan_dh_C PF01315.17 KEY65053.1 - 0.027 14.5 0.2 0.081 13.0 0.1 1.8 1 0 0 1 1 1 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain MscL PF01741.13 KEY65054.1 - 2.6e-15 56.6 0.3 6.7e-15 55.3 0.2 1.6 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL C1_1 PF00130.17 KEY65054.1 - 0.017 14.8 1.3 0.028 14.1 0.9 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2339 PF10101.4 KEY65054.1 - 0.044 12.0 1.3 0.062 11.5 0.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Fer4_11 PF13247.1 KEY65054.1 - 0.066 13.1 1.0 0.16 11.8 0.7 1.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain DZR PF12773.2 KEY65054.1 - 0.11 12.3 0.6 0.17 11.6 0.4 1.2 1 0 0 1 1 1 0 Double zinc ribbon Cullin PF00888.17 KEY65056.1 - 1.1e-206 687.9 2.9 1.5e-206 687.5 2.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KEY65056.1 - 1e-26 92.5 4.8 1e-26 92.5 3.3 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.4 KEY65056.1 - 0.017 15.2 0.1 0.1 12.8 0.1 2.4 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal TrmE_N PF10396.4 KEY65056.1 - 0.022 14.7 0.1 1.1 9.2 0.0 3.2 4 0 0 4 4 4 0 GTP-binding protein TrmE N-terminus Abi_C PF14355.1 KEY65056.1 - 0.055 13.4 0.0 2.2 8.2 0.0 2.9 3 0 0 3 3 3 0 Abortive infection C-terminus WGG PF10273.4 KEY65056.1 - 0.32 11.0 2.7 41 4.3 0.0 3.7 3 0 0 3 3 3 0 Pre-rRNA-processing protein TSR2 PRD PF00874.15 KEY65056.1 - 1.5 9.0 8.9 6.3 6.9 0.4 3.9 4 0 0 4 4 4 0 PRD domain Avl9 PF09794.4 KEY65057.1 - 5.3e-143 476.0 0.0 7e-143 475.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 KEY65057.1 - 9.6e-07 28.4 0.2 0.00023 20.8 0.0 2.3 1 1 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 KEY65057.1 - 1.4e-06 27.7 1.0 3e-05 23.4 0.1 3.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) G-alpha PF00503.15 KEY65058.1 - 1.4e-125 419.0 0.8 1.7e-125 418.7 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KEY65058.1 - 1.1e-15 57.3 0.6 4.1e-10 39.1 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEY65058.1 - 0.00056 19.1 2.7 0.18 10.9 0.1 2.6 1 1 1 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KEY65058.1 - 0.0013 19.2 0.1 1.1 9.7 0.0 2.8 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 KEY65058.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phosphorylase PF00343.15 KEY65059.1 - 0 1072.1 1.0 0 1071.9 0.7 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Coatomer_b_Cpla PF14806.1 KEY65059.1 - 0.073 12.7 0.1 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Pkinase PF00069.20 KEY65060.1 - 2.9e-73 246.2 0.0 3.6e-73 245.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY65060.1 - 6e-32 110.7 0.0 8.9e-32 110.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KEY65060.1 - 2.2e-05 23.6 0.0 7.2e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KEY65060.1 - 0.00019 20.4 0.0 0.021 13.7 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 KEY65060.1 - 0.00044 20.0 0.0 0.0012 18.6 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KEY65060.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family ABC_tran PF00005.22 KEY65061.1 - 1.9e-52 177.1 0.0 2.6e-29 102.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEY65061.1 - 4.8e-27 95.0 30.2 3.7e-16 59.3 2.8 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KEY65061.1 - 4.1e-10 39.2 1.7 0.01 15.1 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEY65061.1 - 4.9e-09 36.5 0.0 0.016 15.2 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 KEY65061.1 - 1.6e-08 34.1 0.0 0.00037 19.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KEY65061.1 - 4.2e-08 33.7 0.2 2.6e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEY65061.1 - 5e-07 29.1 1.6 0.017 14.6 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 KEY65061.1 - 1.3e-05 24.7 0.0 0.067 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain FtsK_SpoIIIE PF01580.13 KEY65061.1 - 4.3e-05 23.0 0.0 0.029 13.8 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 KEY65061.1 - 4.5e-05 23.1 0.4 0.084 12.5 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KEY65061.1 - 5e-05 24.1 0.8 0.38 11.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KEY65061.1 - 7.4e-05 21.9 0.2 0.15 11.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEY65061.1 - 9.5e-05 22.5 0.5 1.2 9.3 0.0 3.5 3 1 0 3 3 2 2 AAA domain Miro PF08477.8 KEY65061.1 - 0.00016 22.1 0.0 0.31 11.5 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein T2SE PF00437.15 KEY65061.1 - 0.00021 20.2 0.1 0.28 10.0 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 KEY65061.1 - 0.00038 20.4 0.2 0.21 11.5 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase DUF87 PF01935.12 KEY65061.1 - 0.00061 19.6 4.5 0.0037 17.1 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_19 PF13245.1 KEY65061.1 - 0.00065 19.4 6.2 0.072 12.8 0.0 4.0 4 0 0 4 4 3 1 Part of AAA domain SbcCD_C PF13558.1 KEY65061.1 - 0.00087 19.1 0.1 1.2 9.1 0.0 2.8 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.17 KEY65061.1 - 0.0016 17.3 0.5 2.5 6.8 0.0 3.4 3 1 0 3 3 3 1 NB-ARC domain Pox_A32 PF04665.7 KEY65061.1 - 0.0019 17.5 1.3 1.2 8.3 0.1 2.3 2 0 0 2 2 2 2 Poxvirus A32 protein Dynamin_N PF00350.18 KEY65061.1 - 0.0022 17.8 0.4 0.8 9.5 0.2 2.7 3 0 0 3 3 2 1 Dynamin family AAA_18 PF13238.1 KEY65061.1 - 0.0025 18.0 0.1 2.8 8.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KEY65061.1 - 0.0028 17.5 0.0 3.5 7.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KEY65061.1 - 0.0038 16.7 1.2 0.91 8.9 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 KEY65061.1 - 0.0048 16.5 3.1 1.5 8.4 0.1 2.9 3 0 0 3 3 3 2 NACHT domain AAA_16 PF13191.1 KEY65061.1 - 0.018 15.0 7.5 2.4 8.1 0.0 3.6 3 1 0 3 3 3 0 AAA ATPase domain Viral_helicase1 PF01443.13 KEY65061.1 - 0.02 14.4 0.0 5.6 6.4 0.0 2.6 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 KEY65061.1 - 0.021 14.7 0.0 1.5 8.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.20 KEY65061.1 - 0.023 14.2 0.0 5.9 6.3 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.12 KEY65061.1 - 0.025 14.1 0.9 3.2 7.2 0.1 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 KEY65061.1 - 0.051 13.2 0.7 9.6 5.8 0.1 2.6 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.1 KEY65061.1 - 0.059 12.9 0.6 2.5 7.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 KEY65061.1 - 0.12 11.4 0.0 9.4 5.1 0.0 2.4 2 0 0 2 2 2 0 Septin Arch_ATPase PF01637.13 KEY65061.1 - 0.14 11.8 0.0 2.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase DEAD PF00270.24 KEY65061.1 - 0.22 11.0 0.1 13 5.2 0.0 2.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase RNA_helicase PF00910.17 KEY65061.1 - 0.28 11.3 1.1 39 4.4 0.0 3.3 3 1 0 3 3 2 0 RNA helicase AAA_5 PF07728.9 KEY65061.1 - 0.32 10.7 1.3 13 5.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KEY65061.1 - 0.38 10.6 1.9 16 5.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.1 KEY65061.1 - 1.3 7.9 0.0 2.4 7.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF1774 PF08611.5 KEY65062.1 - 5.2e-36 122.7 5.1 5.2e-36 122.7 3.6 2.6 3 1 0 3 3 3 1 Fungal protein of unknown function (DUF1774) DUF4231 PF14015.1 KEY65062.1 - 1.7 8.6 6.2 14 5.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Ank_2 PF12796.2 KEY65063.1 - 5.6e-45 151.6 2.4 1.1e-11 44.9 0.0 6.5 3 3 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KEY65063.1 - 4.3e-40 133.5 11.7 1.8e-05 24.3 0.0 12.1 12 0 0 12 12 12 9 Ankyrin repeat Ank_4 PF13637.1 KEY65063.1 - 5.7e-34 115.8 3.0 7.2e-09 35.9 0.0 7.7 8 0 0 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY65063.1 - 5.5e-33 112.2 16.9 7.9e-08 32.3 0.1 9.7 7 2 4 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY65063.1 - 4.1e-27 91.5 9.5 0.00019 21.3 0.0 11.5 11 2 1 12 12 12 6 Ankyrin repeat LysM PF01476.15 KEY65064.1 - 5.3e-17 61.4 0.1 0.00021 21.1 0.0 4.4 4 0 0 4 4 4 4 LysM domain Phage_tail_X PF05489.7 KEY65064.1 - 0.075 12.5 0.2 19 4.8 0.0 2.6 2 0 0 2 2 2 0 Phage Tail Protein X LysM PF01476.15 KEY65065.1 - 1.4e-13 50.5 0.1 2.2e-06 27.4 0.0 3.1 3 0 0 3 3 3 2 LysM domain Phage_tail_X PF05489.7 KEY65065.1 - 0.087 12.3 0.2 0.35 10.3 0.0 2.1 2 0 0 2 2 2 0 Phage Tail Protein X Glyco_hydro_18 PF00704.23 KEY65066.1 - 3e-64 217.6 0.0 4e-64 217.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KEY65066.1 - 2e-08 34.0 37.6 1.9e-07 30.9 4.1 3.7 3 0 0 3 3 3 2 Chitin recognition protein Ank_2 PF12796.2 KEY65067.1 - 1.7e-43 146.8 5.7 3e-09 37.0 0.0 7.5 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEY65067.1 - 1.9e-38 130.1 10.5 4.3e-09 36.6 0.0 9.2 8 1 3 11 11 11 8 Ankyrin repeats (many copies) Ank PF00023.25 KEY65067.1 - 2.8e-36 121.5 16.2 5.9e-06 25.8 0.0 12.7 13 2 0 13 13 13 8 Ankyrin repeat Ank_5 PF13857.1 KEY65067.1 - 1.9e-32 110.5 11.8 1.1e-06 28.6 0.1 8.5 6 2 2 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY65067.1 - 1.6e-26 89.6 2.0 0.00016 21.6 0.0 11.4 11 1 0 11 11 11 5 Ankyrin repeat Glyco_transf_28 PF03033.15 KEY65070.1 - 1.8e-19 69.8 0.1 5e-18 65.2 0.1 2.9 2 1 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KEY65070.1 - 5.6e-05 21.8 0.1 8.6e-05 21.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KEY65070.1 - 0.00018 21.2 0.2 0.00054 19.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.6 KEY65070.1 - 0.0014 18.7 0.0 0.0037 17.3 0.0 1.6 1 0 0 1 1 1 1 ATG C terminal domain Sec61_beta PF03911.11 KEY65071.1 - 9.6e-21 73.3 1.5 1.2e-20 72.9 1.0 1.2 1 0 0 1 1 1 1 Sec61beta family Aconitase PF00330.15 KEY65072.1 - 9e-62 209.0 0.1 1.5e-33 116.0 0.0 3.9 2 1 2 4 4 4 3 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KEY65072.1 - 8.1e-20 71.2 0.0 1.6e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain NIF PF03031.13 KEY65073.1 - 5.2e-52 175.7 0.5 7.3e-52 175.2 0.3 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KEY65073.1 - 0.18 12.0 0.1 1.9 8.6 0.0 2.0 1 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase ABC_membrane_2 PF06472.10 KEY65074.1 - 1.9e-96 322.5 2.8 2e-96 322.4 0.2 2.1 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KEY65074.1 - 1.5e-16 60.9 0.1 3.7e-16 59.6 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KEY65074.1 - 0.0021 18.0 0.0 0.0047 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEY65074.1 - 0.016 16.0 0.1 0.064 14.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 KEY65074.1 - 0.016 15.2 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 KEY65074.1 - 0.018 15.0 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.16 KEY65074.1 - 0.034 13.3 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 KEY65074.1 - 0.056 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KEY65074.1 - 0.08 13.0 0.0 0.2 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KEY65074.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TAF4 PF05236.9 KEY65074.1 - 0.19 10.9 6.9 0.12 11.5 0.9 2.2 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family AAA_23 PF13476.1 KEY65074.1 - 1 9.6 9.1 35 4.6 6.3 2.4 1 1 0 1 1 1 0 AAA domain Aldo_ket_red PF00248.16 KEY65077.1 - 6.8e-51 172.7 0.0 7.8e-51 172.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.2 KEY65078.1 - 3.7e-44 147.6 30.8 5e-13 48.3 2.0 7.3 3 2 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEY65078.1 - 4.7e-28 96.7 53.4 4e-08 32.8 1.8 5.4 2 1 6 8 8 8 6 Leucine rich repeat LRR_1 PF00560.28 KEY65078.1 - 3.6e-14 50.5 21.2 0.15 12.2 0.1 10.5 10 1 1 11 11 11 5 Leucine Rich Repeat LRR_6 PF13516.1 KEY65078.1 - 2.4e-11 42.4 22.4 0.035 14.1 0.3 9.9 8 2 3 11 11 11 4 Leucine Rich repeat LRR_9 PF14580.1 KEY65078.1 - 7e-11 41.9 10.7 1.9e-05 24.3 0.9 4.1 1 1 3 4 4 4 3 Leucine-rich repeat LRR_7 PF13504.1 KEY65078.1 - 3e-10 38.5 19.1 0.59 10.5 0.0 8.7 9 0 0 9 9 9 4 Leucine rich repeat Abhydrolase_6 PF12697.2 KEY65079.1 - 5.1e-12 46.1 2.7 1.1e-11 45.0 1.6 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY65079.1 - 6.1e-11 42.2 0.0 9.4e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KEY65079.1 - 0.00011 21.7 0.1 0.00023 20.8 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEY65079.1 - 0.0018 17.5 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KEY65079.1 - 0.0027 17.3 0.0 0.015 14.8 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold BTB PF00651.26 KEY65080.1 - 9.4e-08 32.0 0.0 4.1e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain PCI PF01399.22 KEY65081.1 - 1.3e-11 44.7 0.0 2.9e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_11 PF13414.1 KEY65081.1 - 0.0014 18.2 0.2 0.0042 16.6 0.2 1.8 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 KEY65081.1 - 0.027 14.0 0.4 0.079 12.6 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_L18ae PF01775.12 KEY65082.1 - 3.5e-57 191.6 0.2 4.8e-57 191.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Fungal_trans PF04082.13 KEY65083.1 - 8.8e-18 64.1 0.1 1.8e-17 63.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY65083.1 - 2e-08 34.0 12.1 3.8e-08 33.1 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_3 PF13302.1 KEY65084.1 - 2.5e-38 131.4 0.0 3.1e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KEY65084.1 - 0.0031 17.4 0.1 0.16 11.8 0.1 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF3018 PF11455.3 KEY65084.1 - 0.024 14.5 0.1 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3018) Acetyltransf_1 PF00583.19 KEY65084.1 - 0.12 12.4 0.1 2.7 8.0 0.0 2.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family DUF1772 PF08592.6 KEY65085.1 - 8.3e-22 77.4 8.9 1.1e-21 77.0 6.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) TMEM237 PF15383.1 KEY65085.1 - 0.022 13.8 0.1 0.028 13.5 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 COX6A PF02046.10 KEY65085.1 - 0.11 12.3 0.3 2.2 8.2 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIa Herpes_capsid PF06112.6 KEY65086.1 - 0.031 14.3 1.0 0.036 14.1 0.7 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein AT_hook PF02178.14 KEY65086.1 - 0.053 13.2 6.4 0.14 11.8 4.4 1.8 1 0 0 1 1 1 0 AT hook motif Ric8 PF10165.4 KEY65087.1 - 5.8e-122 407.7 0.0 6.5e-122 407.5 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Rif1_N PF12231.3 KEY65088.1 - 5e-129 430.5 0.2 8.4e-129 429.7 0.1 1.4 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal AIF_C PF14721.1 KEY65088.1 - 3.1 8.0 7.3 3 8.1 3.2 2.4 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Sugar_tr PF00083.19 KEY65089.1 - 5.7e-107 358.0 20.1 7.1e-107 357.7 13.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY65089.1 - 9e-23 80.5 32.7 8.7e-15 54.2 4.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEY65089.1 - 4.8e-07 28.5 25.3 0.00035 19.1 1.5 3.3 2 1 1 3 3 3 3 MFS/sugar transport protein OATP PF03137.15 KEY65089.1 - 0.0062 14.6 0.3 0.012 13.7 0.2 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Aldose_epim PF01263.15 KEY65090.1 - 2.1e-40 138.7 0.0 2.6e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF4432 PF14486.1 KEY65090.1 - 0.13 10.7 0.0 0.33 9.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) DAHP_synth_2 PF01474.11 KEY65091.1 - 2.4e-192 639.1 0.0 2.7e-192 638.9 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Secretin_N PF03958.12 KEY65092.1 - 0.087 13.0 4.0 0.14 12.3 2.8 1.3 1 1 0 1 1 1 0 Bacterial type II/III secretion system short domain DUF959 PF06121.9 KEY65092.1 - 0.19 11.3 2.5 0.23 11.0 1.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF959) DUF4349 PF14257.1 KEY65092.1 - 10 5.2 8.7 18 4.4 6.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) BRCT PF00533.21 KEY65093.1 - 0.064 13.4 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Asp PF00026.18 KEY65094.1 - 1.9e-61 208.0 0.0 2.3e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEY65094.1 - 1.3e-07 31.6 0.0 1.5e-05 25.0 0.0 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KEY65094.1 - 0.0013 19.2 0.0 19 5.8 0.0 3.4 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 KEY65094.1 - 0.01 15.6 0.0 6.6 6.6 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.1 KEY65094.1 - 0.057 12.9 0.0 3.8 7.0 0.0 2.6 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal GTP_EFTU PF00009.22 KEY65095.1 - 8.2e-57 191.6 0.2 1.4e-56 190.9 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KEY65095.1 - 4.7e-31 106.4 0.0 1e-30 105.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 KEY65095.1 - 4.8e-27 93.9 0.0 1.2e-26 92.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KEY65095.1 - 1.9e-22 78.9 0.0 4.3e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KEY65095.1 - 6.1e-13 48.6 0.0 1.3e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF442 PF04273.8 KEY65095.1 - 0.021 14.6 0.3 0.56 10.0 0.0 3.0 3 0 0 3 3 3 0 Putative phosphatase (DUF442) FAD_binding_3 PF01494.14 KEY65097.1 - 1.3e-17 63.9 0.0 2.3e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KEY65097.1 - 6e-06 26.1 0.0 1.8e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KEY65097.1 - 6.7e-05 23.2 0.0 0.00026 21.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEY65097.1 - 0.00018 20.5 0.0 0.00028 19.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEY65097.1 - 0.0023 17.8 0.0 0.0053 16.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEY65097.1 - 0.0038 15.7 0.0 0.0061 15.0 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.16 KEY65097.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.5 KEY65097.1 - 0.031 13.1 0.0 0.07 11.9 0.0 1.5 1 0 0 1 1 1 0 Squalene epoxidase GIDA PF01134.17 KEY65097.1 - 0.037 12.8 0.0 0.073 11.9 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A XdhC_C PF13478.1 KEY65097.1 - 0.058 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain FAD_oxidored PF12831.2 KEY65097.1 - 0.084 11.9 0.0 0.34 9.9 0.0 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase Peptidase_M24 PF00557.19 KEY65098.1 - 2.3e-40 138.4 0.1 2.9e-40 138.0 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KEY65098.1 - 0.00018 21.3 4.0 0.00018 21.3 2.8 2.2 2 0 0 2 2 2 1 MYND finger Dynein_light PF01221.13 KEY65099.1 - 2.6e-41 139.5 1.5 3e-41 139.2 1.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 RRM_1 PF00076.17 KEY65100.1 - 2.2e-72 238.6 0.1 1e-18 66.6 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY65100.1 - 4.9e-64 212.2 0.0 2e-15 56.5 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY65100.1 - 1e-33 114.9 0.0 2.1e-08 33.8 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KEY65100.1 - 4.3e-05 23.2 0.0 3.6 7.4 0.0 5.0 5 0 0 5 5 5 1 RNA binding motif Nup35_RRM_2 PF14605.1 KEY65100.1 - 0.00013 21.6 0.0 3.4 7.5 0.0 4.0 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif TEA PF01285.13 KEY65101.1 - 1e-16 61.1 0.2 9.3e-13 48.1 0.0 2.7 2 0 0 2 2 2 2 TEA/ATTS domain family Pro_isomerase PF00160.16 KEY65104.1 - 5.4e-48 163.1 0.2 6.3e-48 162.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.1 KEY65104.1 - 0.074 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain zf-RING_2 PF13639.1 KEY65105.1 - 1.1e-13 50.7 6.4 1.7e-13 50.1 4.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KEY65105.1 - 4.8e-08 32.5 3.2 7.7e-08 31.8 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEY65105.1 - 1e-07 31.9 2.4 2e-07 31.0 1.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KEY65105.1 - 6.3e-06 25.8 3.7 9.9e-06 25.1 2.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEY65105.1 - 2.1e-05 24.4 4.9 3.4e-05 23.7 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEY65105.1 - 4.5e-05 23.0 2.1 6.6e-05 22.4 1.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEY65105.1 - 0.002 17.8 3.2 0.005 16.6 2.2 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KEY65105.1 - 0.019 14.5 6.2 0.031 13.8 4.3 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 KEY65105.1 - 0.11 12.2 5.5 0.18 11.5 3.8 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.1 KEY65105.1 - 0.2 11.5 4.3 0.4 10.6 3.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KEY65105.1 - 0.45 10.5 2.7 1.2 9.1 1.8 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 KEY65105.1 - 0.67 10.0 5.2 1.2 9.2 3.6 1.4 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 KEY65105.1 - 2.2 8.0 8.3 7.7 6.3 5.1 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 DUF3752 PF12572.3 KEY65106.1 - 1.7e-41 141.8 12.0 3.3e-41 140.9 8.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) Vps8 PF12816.2 KEY65107.1 - 8.2e-72 240.5 0.0 1.7e-71 239.5 0.0 1.6 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 PIG-P PF08510.7 KEY65107.1 - 8.4e-40 135.3 0.1 1.7e-39 134.2 0.1 1.6 1 0 0 1 1 1 1 PIG-P Clathrin PF00637.15 KEY65107.1 - 1e-07 31.6 0.0 0.00013 21.6 0.0 3.0 4 0 0 4 4 4 2 Region in Clathrin and VPS DUF4160 PF13711.1 KEY65107.1 - 0.073 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) DEAD PF00270.24 KEY65108.1 - 3.2e-23 82.0 0.1 7.3e-22 77.6 0.0 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY65108.1 - 2e-22 78.8 0.1 7.4e-22 77.0 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEY65108.1 - 0.00018 21.3 0.1 0.00045 20.0 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit tRNA-synt_2 PF00152.15 KEY65109.1 - 2.1e-70 237.1 0.0 2.8e-69 233.4 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KEY65109.1 - 2.2e-11 43.4 0.0 8.6e-11 41.5 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KEY65109.1 - 6.8e-06 25.4 0.0 0.0038 16.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KEY65109.1 - 0.0011 18.6 0.0 0.3 10.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HPIP PF15226.1 KEY65109.1 - 0.025 14.6 0.1 0.073 13.1 0.1 1.8 1 0 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family Actin PF00022.14 KEY65110.1 - 1e-143 478.5 0.0 1.2e-143 478.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KEY65110.1 - 7.9e-07 27.9 0.2 0.0035 15.9 0.0 2.5 3 0 0 3 3 3 2 MreB/Mbl protein Hydantoinase_A PF01968.13 KEY65110.1 - 0.063 12.3 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase UDG PF03167.14 KEY65111.1 - 1.7e-23 82.7 0.1 8.6e-23 80.4 0.0 1.8 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily TMEM171 PF15471.1 KEY65111.1 - 1.4 7.6 3.0 1.9 7.2 2.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Pol_alpha_B_N PF08418.5 KEY65111.1 - 5.5 6.4 6.5 8.2 5.8 4.5 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal UDPGP PF01704.13 KEY65112.1 - 2.3e-54 184.4 0.0 3.3e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 KEY65112.1 - 0.025 14.6 0.1 0.078 13.0 0.0 1.8 2 0 0 2 2 2 0 MobA-like NTP transferase domain Pyr_redox_2 PF07992.9 KEY65113.1 - 1.4e-26 93.6 0.1 1.8e-26 93.3 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY65113.1 - 5.8e-17 61.8 0.1 2.1e-15 56.8 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY65113.1 - 2.9e-08 34.0 0.5 9.2e-05 22.5 0.0 3.0 1 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEY65113.1 - 0.00013 21.0 4.0 0.19 10.5 0.0 3.6 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY65113.1 - 0.00071 19.5 0.1 0.041 13.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 KEY65113.1 - 0.0015 18.7 0.1 0.024 14.8 0.0 2.5 2 2 0 2 2 2 1 Putative NAD(P)-binding K_oxygenase PF13434.1 KEY65113.1 - 0.0024 16.8 0.1 0.26 10.1 0.0 2.6 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 KEY65113.1 - 0.0035 16.2 2.1 2.3 6.9 0.1 3.8 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 KEY65113.1 - 0.0047 16.0 0.2 1.2 8.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 KEY65113.1 - 0.0078 15.3 0.0 0.024 13.7 0.0 1.8 1 0 0 1 1 1 1 Thi4 family Shikimate_DH PF01488.15 KEY65113.1 - 0.039 14.0 0.1 2.2 8.3 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 KEY65113.1 - 0.13 11.1 5.8 2.5 6.8 2.4 3.0 1 1 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 KEY65113.1 - 0.16 11.7 1.3 6.2 6.5 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Vps53_N PF04100.7 KEY65114.1 - 1.5e-102 343.2 0.3 2.5e-102 342.5 0.2 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 KEY65114.1 - 2.4e-11 43.0 3.6 4.7e-11 42.1 2.5 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Spc7 PF08317.6 KEY65114.1 - 0.00045 18.9 1.2 0.00079 18.1 0.8 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF892 PF05974.7 KEY65114.1 - 0.0078 16.0 4.3 0.0078 16.0 3.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF892) Baculo_PEP_C PF04513.7 KEY65114.1 - 0.018 14.8 3.5 0.044 13.6 2.1 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Zw10 PF06248.8 KEY65114.1 - 0.059 11.5 7.0 0.011 13.8 2.1 1.7 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 COG2 PF06148.6 KEY65114.1 - 0.45 10.3 5.1 1.7 8.5 2.0 3.1 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 fn3 PF00041.16 KEY65115.1 - 4.7e-06 26.6 0.1 1.7e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III domain IF-2B PF01008.12 KEY65115.1 - 0.27 10.1 3.2 0.5 9.3 2.2 1.3 1 0 0 1 1 1 0 Initiation factor 2 subunit family LNS2 PF08235.8 KEY65116.1 - 1.2e-71 239.3 0.1 1.8e-71 238.7 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KEY65116.1 - 1e-40 137.8 0.0 1.8e-39 133.7 0.0 2.4 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 KEY65116.1 - 2.3e-05 23.8 0.0 0.017 14.5 0.0 2.8 3 0 0 3 3 3 2 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF1179 PF06678.6 KEY65116.1 - 0.16 12.2 0.4 0.7 10.2 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) Histidinol_dh PF00815.15 KEY65117.1 - 9.1e-181 600.9 5.6 1.6e-180 600.1 3.9 1.4 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 KEY65117.1 - 1e-22 79.4 0.0 2e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 KEY65117.1 - 1.5e-10 41.1 0.2 1.5e-10 41.1 0.2 2.7 3 0 0 3 3 3 1 Phosphoribosyl-ATP pyrophosphohydrolase TFIID-31kDa PF02291.10 KEY65118.1 - 2.1e-27 95.4 0.0 3.9e-26 91.3 0.0 2.1 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Peptidase_M16 PF00675.15 KEY65119.1 - 8.5e-59 197.5 0.3 1.6e-58 196.6 0.2 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KEY65119.1 - 3.8e-41 140.8 0.0 2.5e-40 138.1 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain Raffinose_syn PF05691.7 KEY65120.1 - 4.6e-56 189.8 0.9 2.8e-43 147.5 0.2 3.0 2 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 KEY65120.1 - 0.00043 19.0 0.5 0.00071 18.3 0.3 1.3 1 0 0 1 1 1 1 Melibiase ocr PF08684.5 KEY65120.1 - 0.022 14.8 0.2 0.051 13.6 0.1 1.5 1 0 0 1 1 1 0 DNA mimic ocr IMPDH PF00478.20 KEY65121.1 - 8.3e-132 439.3 1.2 1e-131 439.0 0.9 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KEY65121.1 - 4.8e-15 55.0 0.1 2.7e-07 30.2 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 KEY65121.1 - 1.5e-07 30.5 1.7 3e-06 26.3 0.4 2.3 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 KEY65121.1 - 1.3e-06 27.7 6.3 0.031 13.4 0.0 2.6 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.16 KEY65121.1 - 0.00059 19.1 2.1 0.014 14.7 1.5 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 KEY65121.1 - 0.031 13.3 1.2 0.1 11.6 0.2 2.0 2 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG PK PF00224.16 KEY65121.1 - 0.076 11.6 0.0 0.18 10.3 0.0 1.5 1 1 0 1 1 1 0 Pyruvate kinase, barrel domain Acetyltransf_1 PF00583.19 KEY65122.1 - 6.6e-10 38.8 0.0 1.8e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KEY65122.1 - 1.3e-05 25.2 0.0 3.1e-05 24.0 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KEY65122.1 - 0.00023 21.2 0.0 0.00036 20.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEY65122.1 - 0.04 13.6 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.1 KEY65122.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KEY65122.1 - 0.06 13.2 0.0 2.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Complex1_LYR_1 PF13232.1 KEY65123.1 - 4.3e-16 58.8 0.1 7.6e-16 58.0 0.1 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KEY65123.1 - 1.6e-15 56.6 1.3 2.8e-15 55.8 0.2 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 KEY65123.1 - 0.017 15.5 0.6 0.026 15.0 0.4 1.4 1 1 0 1 1 1 0 Complex1_LYR-like Ribosomal_L36 PF00444.13 KEY65124.1 - 9.6e-21 73.4 11.2 1.3e-20 73.0 7.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 KTI12 PF08433.5 KEY65124.1 - 0.11 11.7 0.0 0.12 11.5 0.0 1.0 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PH_6 PF15406.1 KEY65126.1 - 2.6e-40 136.9 1.5 1e-39 135.0 1.1 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KEY65126.1 - 0.025 14.7 0.0 0.059 13.5 0.0 1.7 1 0 0 1 1 1 0 PH domain PH_4 PF15404.1 KEY65126.1 - 0.13 11.7 0.5 0.44 10.0 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain HATPase_c PF02518.21 KEY65127.1 - 7.6e-23 80.3 0.1 1.6e-22 79.2 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KEY65127.1 - 4.5e-21 74.9 0.2 9e-21 73.9 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 KEY65127.1 - 2.9e-11 43.6 0.0 3.1e-08 33.9 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 KEY65127.1 - 1.1e-10 41.5 0.0 0.00011 22.2 0.0 2.8 2 0 0 2 2 2 2 PAS fold HisKA PF00512.20 KEY65127.1 - 1e-07 31.8 0.1 3.4e-07 30.1 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 KEY65127.1 - 2.5e-06 27.2 0.1 0.00043 20.0 0.0 2.8 2 0 0 2 2 2 1 PAS fold GAF_2 PF13185.1 KEY65127.1 - 3.1e-05 24.5 0.0 0.012 16.1 0.0 2.6 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.1 KEY65127.1 - 0.023 14.7 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 0 GAF domain PAS_8 PF13188.1 KEY65127.1 - 0.029 14.2 0.0 0.25 11.2 0.0 2.4 2 0 0 2 2 2 0 PAS domain Rer1 PF03248.8 KEY65129.1 - 0.18 11.3 0.0 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 Rer1 family Phtf-FEM1B_bdg PF12129.3 KEY65129.1 - 1.9 7.8 7.2 2.1 7.6 0.9 2.6 3 0 0 3 3 3 0 Male germ-cell putative homeodomain transcription factor DUF809 PF05663.6 KEY65129.1 - 3.1 7.7 5.5 6.2 6.7 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF809) Aldedh PF00171.17 KEY65130.1 - 2.8e-160 533.6 0.0 5.2e-160 532.7 0.0 1.3 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRF PF01765.14 KEY65130.1 - 2.4e-26 92.1 1.0 3.4e-26 91.6 0.7 1.2 1 0 0 1 1 1 1 Ribosome recycling factor DUF1487 PF07368.6 KEY65130.1 - 0.0018 17.5 0.0 0.0049 16.1 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Metallophos PF00149.23 KEY65132.1 - 1.1e-38 132.6 0.2 1.4e-38 132.3 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SUR7 PF06687.7 KEY65133.1 - 7.7e-32 110.5 5.2 9.4e-32 110.2 3.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family Tweety PF04906.8 KEY65133.1 - 0.0022 16.4 5.6 0.24 9.7 2.3 2.2 2 0 0 2 2 2 2 Tweety RCR PF12273.3 KEY65133.1 - 0.0036 17.8 0.0 0.0036 17.8 0.0 2.1 3 0 0 3 3 3 1 Chitin synthesis regulation, resistance to Congo red WD40 PF00400.27 KEY65134.1 - 2.2e-22 78.0 11.4 2.4e-07 30.3 0.0 9.6 12 0 0 12 12 12 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KEY65134.1 - 0.027 13.2 0.1 10 4.7 0.0 4.0 4 1 0 4 4 4 0 Nup133 N terminal like DUF4121 PF13497.1 KEY65134.1 - 0.14 11.1 0.0 0.42 9.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4121) DUF4140 PF13600.1 KEY65135.1 - 0.5 10.8 5.3 0.16 12.4 0.8 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) ADH_N PF08240.7 KEY65137.1 - 5.1e-27 93.7 1.2 9.2e-27 92.9 0.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY65137.1 - 5.4e-17 61.5 0.0 8.4e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase S1-like PF14444.1 KEY65137.1 - 0.037 13.7 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 S1-like UDPG_MGDP_dh_N PF03721.9 KEY65137.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ATP-synt_G PF04718.10 KEY65138.1 - 2.3e-27 95.6 0.9 5.5e-27 94.4 0.1 1.8 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Methyltransf_23 PF13489.1 KEY65139.1 - 4.6e-13 49.1 0.0 8.5e-13 48.3 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY65139.1 - 1e-05 26.0 0.0 4.8e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KEY65139.1 - 2.9e-05 24.1 0.0 4.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 KEY65139.1 - 0.00031 21.0 0.0 0.00075 19.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY65139.1 - 0.00037 20.9 0.0 0.0006 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY65139.1 - 0.00046 20.2 0.0 0.0022 18.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY65139.1 - 0.00067 19.2 0.0 0.0016 18.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEY65139.1 - 0.00097 18.3 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 KEY65139.1 - 0.0019 18.6 0.0 0.0062 16.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY65139.1 - 0.0028 17.0 0.0 0.022 14.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.4 KEY65139.1 - 0.0055 16.1 0.0 0.0078 15.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase TFIIA PF03153.8 KEY65140.1 - 6.5e-80 269.8 12.2 9.4e-80 269.3 8.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 KEY65141.1 - 4.5e-26 89.7 17.6 1.6e-06 27.7 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KEY65141.1 - 1.7e-07 31.1 0.4 7.4e-05 22.5 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A CDK2AP PF09806.4 KEY65141.1 - 0.021 15.0 1.5 0.05 13.8 1.1 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Apc4_WD40 PF12894.2 KEY65141.1 - 0.023 14.2 0.0 0.54 9.7 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.2 KEY65141.1 - 4.4 6.9 7.7 2.9 7.5 0.0 3.4 3 2 1 4 4 4 0 Transcription factor IIIC subunit delta N-term Kelch_4 PF13418.1 KEY65142.1 - 7.9e-27 92.7 6.5 3.6e-08 33.0 0.0 5.0 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KEY65142.1 - 3.3e-25 87.5 1.4 2.9e-07 30.3 0.0 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 KEY65142.1 - 1.4e-23 82.0 1.2 0.00017 21.6 0.1 4.9 3 1 1 4 4 4 4 Kelch motif Kelch_1 PF01344.20 KEY65142.1 - 2.9e-21 74.7 0.1 1.7e-05 24.2 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.1 KEY65142.1 - 5.6e-20 70.9 7.6 6.3e-07 29.3 0.0 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KEY65142.1 - 1.5e-19 68.9 2.2 0.00032 20.3 0.0 4.7 4 0 0 4 4 4 4 Kelch motif BTB PF00651.26 KEY65142.1 - 1.5e-09 37.8 0.0 2.6e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Rax2 PF12768.2 KEY65142.1 - 0.12 11.6 0.0 0.48 9.6 0.0 1.8 1 1 1 2 2 2 0 Cortical protein marker for cell polarity zf-C2H2_jaz PF12171.3 KEY65143.1 - 0.00083 19.4 2.2 0.038 14.1 0.1 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KEY65143.1 - 0.003 17.7 14.0 0.38 11.2 0.2 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY65143.1 - 0.019 15.2 16.6 0.28 11.5 0.8 4.7 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KEY65143.1 - 0.029 14.6 0.7 0.029 14.6 0.5 3.5 4 0 0 4 4 4 0 Zinc-finger double domain HIG_1_N PF04588.8 KEY65144.1 - 2.1e-06 27.3 4.3 9.5e-06 25.2 3.0 2.2 1 1 0 1 1 1 1 Hypoxia induced protein conserved region Romo1 PF10247.4 KEY65144.1 - 0.036 14.2 1.9 0.067 13.3 1.3 1.4 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Clc-like PF07062.7 KEY65144.1 - 0.091 11.9 0.1 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Clc-like Bud13 PF09736.4 KEY65144.1 - 4.3 7.5 8.2 0.19 12.0 0.4 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Kelch_4 PF13418.1 KEY65145.1 - 1.1e-41 140.3 18.7 5.2e-10 38.9 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KEY65145.1 - 1.8e-40 136.2 14.9 5.2e-07 29.4 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 KEY65145.1 - 3.4e-40 135.3 26.5 1.2e-08 34.8 0.0 7.6 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_1 PF01344.20 KEY65145.1 - 8.5e-38 127.6 18.9 1.1e-07 31.2 0.5 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KEY65145.1 - 4.8e-34 115.1 16.3 1.3e-06 28.3 0.0 6.4 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.10 KEY65145.1 - 9.4e-33 110.7 16.2 2.6e-08 33.3 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Dus PF01207.12 KEY65146.1 - 2.4e-38 131.7 0.0 2.1e-28 99.0 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) Peroxin-13_N PF04088.8 KEY65147.1 - 8e-57 191.6 0.0 1.4e-56 190.8 0.0 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 KEY65147.1 - 1e-09 37.7 0.0 1.7e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KEY65147.1 - 4.3e-08 32.4 0.0 7.4e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KEY65147.1 - 8.9e-08 31.6 0.1 1.5e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 KEY65147.1 - 0.058 13.5 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain LigD_N PF13298.1 KEY65148.1 - 1.9e-14 53.6 0.0 1.3e-13 50.9 0.0 2.2 1 1 1 2 2 2 1 DNA polymerase Ligase (LigD) Secretin_N_2 PF07655.8 KEY65148.1 - 9.7 6.6 10.3 25 5.3 7.1 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain WD40 PF00400.27 KEY65149.1 - 2.3e-26 90.6 14.1 2e-07 30.6 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KEY65149.1 - 2.2e-05 24.2 0.2 0.088 12.5 0.0 3.3 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A ABC_tran PF00005.22 KEY65150.1 - 1.4e-52 177.6 0.0 9.8e-30 103.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEY65150.1 - 4.4e-32 111.6 26.1 2.1e-24 86.4 4.8 2.6 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KEY65150.1 - 4.5e-11 42.3 0.0 2.2e-05 23.8 0.0 4.2 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KEY65150.1 - 4e-06 26.3 0.1 0.0024 17.2 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.1 KEY65150.1 - 4e-05 23.7 0.1 0.49 10.3 0.0 3.7 3 1 1 4 4 4 1 AAA domain AAA_16 PF13191.1 KEY65150.1 - 4.8e-05 23.4 0.7 0.081 12.9 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 KEY65150.1 - 0.0002 20.3 0.0 0.061 12.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF258 PF03193.11 KEY65150.1 - 0.00066 18.9 0.1 0.23 10.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KEY65150.1 - 0.001 18.5 2.5 0.8 9.2 0.2 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KEY65150.1 - 0.0025 17.9 0.2 10 6.3 0.0 3.6 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KEY65150.1 - 0.0032 17.8 4.0 0.022 15.0 0.3 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KEY65150.1 - 0.0033 17.3 0.3 0.51 10.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KEY65150.1 - 0.013 15.9 1.0 5.5 7.5 0.1 2.6 2 0 0 2 2 2 0 Miro-like protein DUF2075 PF09848.4 KEY65150.1 - 0.024 13.5 0.2 0.35 9.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.12 KEY65150.1 - 0.03 14.1 2.8 0.84 9.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_10 PF12846.2 KEY65150.1 - 0.035 13.5 0.4 1.4 8.3 0.1 2.7 2 1 0 2 2 2 0 AAA-like domain SbcCD_C PF13558.1 KEY65150.1 - 0.051 13.4 0.0 6.7 6.6 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 KEY65150.1 - 0.079 13.1 0.1 65 3.7 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA PF00004.24 KEY65151.1 - 0.00033 20.8 0.0 0.00072 19.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KEY65151.1 - 0.027 13.4 0.0 0.049 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PPK2 PF03976.9 KEY65151.1 - 0.095 11.9 0.0 0.6 9.3 0.0 2.0 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) APG6 PF04111.7 KEY65152.1 - 2e-128 427.8 0.0 2.5e-128 427.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 zf-C4H2 PF10146.4 KEY65152.1 - 0.0011 19.0 4.1 0.0011 19.0 2.9 1.8 2 0 0 2 2 2 1 Zinc finger-containing protein DUF342 PF03961.8 KEY65152.1 - 0.06 11.7 2.0 0.086 11.2 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Seryl_tRNA_N PF02403.17 KEY65152.1 - 0.47 10.4 11.3 0.12 12.4 1.5 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.14 KEY65152.1 - 1.2 6.8 5.2 1.7 6.4 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KEY65152.1 - 2.8 7.4 9.4 5.1 6.6 6.5 1.4 1 0 0 1 1 1 0 IncA protein Scm3 PF10384.4 KEY65153.1 - 3.1e-20 71.3 0.1 6.6e-20 70.3 0.1 1.6 1 0 0 1 1 1 1 Centromere protein Scm3 Pkinase PF00069.20 KEY65154.1 - 1.2e-59 201.6 0.1 1.4e-59 201.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY65154.1 - 1.5e-19 70.1 0.0 2.1e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEY65154.1 - 1.6e-09 37.8 0.0 4.9e-06 26.4 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEY65154.1 - 0.006 16.1 0.3 0.014 14.9 0.2 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KEY65154.1 - 0.046 12.7 0.0 0.071 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KEY65154.1 - 0.071 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF3807 PF12720.2 KEY65155.1 - 6.1e-32 111.1 1.1 7.3e-32 110.8 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) DUF488 PF04343.8 KEY65156.1 - 1.4 9.3 5.2 2.9 8.3 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF488 TPR_7 PF13176.1 KEY65156.1 - 2 8.4 5.9 2.1 8.3 0.2 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat Atg14 PF10186.4 KEY65157.1 - 2.2e-82 276.3 0.0 2.6e-82 276.1 0.0 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 YebG PF07130.7 KEY65157.1 - 0.11 12.2 2.3 0.26 11.0 1.5 1.7 1 1 0 1 1 1 0 YebG protein DUF4200 PF13863.1 KEY65157.1 - 0.83 9.6 7.1 0.11 12.4 1.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Spc7_N PF15402.1 KEY65159.1 - 2.9e-234 780.1 94.6 2.9e-234 780.1 65.5 3.0 2 1 0 2 2 2 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 KEY65159.1 - 3.2e-113 377.7 7.8 3.2e-113 377.7 5.4 1.9 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 KEY65159.1 - 9.9e-20 69.9 0.2 2.1e-19 68.9 0.1 1.5 1 0 0 1 1 1 1 Spc7_C2 DivIC PF04977.10 KEY65159.1 - 0.088 12.3 1.7 0.43 10.1 1.2 2.2 1 0 0 1 1 1 0 Septum formation initiator Ribosomal_S17 PF00366.15 KEY65160.1 - 1.5e-30 105.0 1.3 2.3e-30 104.4 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 DUF1719 PF08224.6 KEY65161.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) Prefoldin_3 PF13758.1 KEY65163.1 - 4.4e-29 100.1 0.8 4.4e-29 100.1 0.6 2.1 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.2 KEY65163.1 - 3.5e-16 59.9 0.1 3.5e-16 59.9 0.1 5.3 6 1 0 6 6 6 1 Domain of unknown function (DUF3835) Prefoldin_2 PF01920.15 KEY65163.1 - 0.00079 19.1 1.6 0.032 13.9 0.0 3.2 3 0 0 3 3 3 1 Prefoldin subunit TMF_DNA_bd PF12329.3 KEY65163.1 - 0.026 14.3 2.2 6.4 6.6 0.2 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Prefoldin PF02996.12 KEY65163.1 - 0.059 13.0 1.7 0.23 11.1 0.2 2.3 2 0 0 2 2 2 0 Prefoldin subunit FliJ PF02050.11 KEY65163.1 - 0.15 12.0 2.7 0.49 10.4 0.0 2.5 2 0 0 2 2 2 0 Flagellar FliJ protein DUF2057 PF09829.4 KEY65163.1 - 0.28 10.8 4.2 0.92 9.1 2.9 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) MerR-DNA-bind PF09278.6 KEY65163.1 - 0.83 10.0 0.0 0.83 10.0 0.0 3.5 3 1 1 4 4 4 0 MerR, DNA binding GFA PF04828.9 KEY65164.1 - 8.7e-16 57.6 1.5 2.2e-08 33.9 0.8 2.7 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Mur_ligase_M PF08245.7 KEY65164.1 - 0.00019 21.5 0.1 0.0023 18.0 0.1 2.4 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 KEY65164.1 - 0.086 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Mitofilin PF09731.4 KEY65165.1 - 4.7e-143 477.9 12.6 7e-143 477.3 8.7 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Mur_ligase_M PF08245.7 KEY65165.1 - 0.049 13.6 2.1 0.15 12.0 0.2 2.6 2 1 0 2 2 2 0 Mur ligase middle domain Ras PF00071.17 KEY65166.1 - 5.5e-58 194.9 0.1 6.4e-58 194.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEY65166.1 - 3.1e-19 69.6 0.1 5.4e-19 68.8 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KEY65166.1 - 6e-15 54.9 0.0 7.6e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEY65166.1 - 5.5e-08 32.2 0.0 6.4e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KEY65166.1 - 1.3e-07 31.2 0.0 1.9e-07 30.7 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEY65166.1 - 1.4e-05 24.9 0.0 2.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KEY65166.1 - 0.047 13.8 0.1 2.7 8.1 0.0 2.5 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KEY65166.1 - 0.056 12.6 0.2 0.22 10.6 0.0 2.0 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KEY65166.1 - 0.12 12.3 0.6 0.38 10.7 0.4 1.9 1 1 0 1 1 1 0 AAA ATPase domain Syja_N PF02383.13 KEY65167.1 - 8.9e-89 297.3 0.0 1.1e-88 297.0 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain PP2C PF00481.16 KEY65168.1 - 8e-56 189.2 0.0 1.4e-55 188.5 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 KEY65168.1 - 1.3e-55 184.2 62.5 8.3e-08 31.6 0.0 13.8 10 3 5 15 15 15 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEY65168.1 - 1.8e-39 133.3 66.3 2.2e-10 40.1 0.2 11.4 6 3 8 14 14 14 11 Leucine rich repeat Guanylate_cyc PF00211.15 KEY65168.1 - 1.1e-27 96.5 0.0 2.2e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 KEY65168.1 - 1e-23 79.6 58.8 0.24 11.5 0.0 21.3 21 2 0 21 21 21 8 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.6 KEY65168.1 - 8.6e-19 66.6 3.2 1.2e-18 66.1 0.9 2.3 2 0 0 2 2 2 1 Adenylate cyclase G-alpha binding domain LRR_7 PF13504.1 KEY65168.1 - 1.7e-17 60.4 45.1 0.36 11.2 0.1 18.6 20 0 0 20 20 20 5 Leucine rich repeat RA PF00788.18 KEY65168.1 - 9.9e-08 32.3 0.0 3e-07 30.8 0.0 1.8 2 0 0 2 2 1 1 Ras association (RalGDS/AF-6) domain LRR_6 PF13516.1 KEY65168.1 - 0.0039 17.0 53.7 4.1 7.7 0.0 17.3 19 2 2 21 21 21 1 Leucine Rich repeat LRR_5 PF13306.1 KEY65168.1 - 0.019 14.6 0.8 7.6 6.2 0.1 3.7 3 1 1 4 4 4 0 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KEY65168.1 - 1.4 8.4 13.1 1.3 8.5 0.4 4.0 2 1 2 5 5 5 0 Leucine-rich repeat Glyco_transf_22 PF03901.12 KEY65169.1 - 1.9e-39 135.8 16.5 2.4e-39 135.5 11.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Yos1 PF08571.5 KEY65170.1 - 2.9e-27 94.5 1.5 3.3e-27 94.4 1.1 1.0 1 0 0 1 1 1 1 Yos1-like UCH PF00443.24 KEY65171.1 - 6.7e-61 205.7 0.1 9.4e-61 205.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEY65171.1 - 1.5e-28 100.0 1.5 1.3e-22 80.6 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 KEY65171.1 - 0.097 11.9 3.2 2.2 7.5 0.8 2.5 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase CBS PF00571.23 KEY65173.1 - 9.5e-06 25.3 0.1 0.055 13.2 0.0 3.0 2 1 0 2 2 2 2 CBS domain DUF4350 PF14258.1 KEY65173.1 - 0.075 13.2 0.1 0.35 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) Epimerase PF01370.16 KEY65175.1 - 1.6e-20 73.5 0.0 2.3e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KEY65175.1 - 5.3e-08 32.0 0.0 7.7e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KEY65175.1 - 4.4e-07 29.9 0.0 1.6e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KEY65175.1 - 8.7e-06 25.8 0.0 2.4e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Ldh_1_N PF00056.18 KEY65175.1 - 0.0036 17.1 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain KR PF08659.5 KEY65175.1 - 0.0047 16.6 0.0 0.01 15.5 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.7 KEY65175.1 - 0.0077 15.1 0.0 0.013 14.4 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KEY65175.1 - 0.0096 14.6 0.0 0.079 11.6 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 KEY65175.1 - 0.012 14.6 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase TrkA_N PF02254.13 KEY65175.1 - 0.066 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain F_actin_cap_B PF01115.12 KEY65176.1 - 3.1e-108 360.5 0.0 3.6e-108 360.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit APH PF01636.18 KEY65177.1 - 8.8e-13 48.5 0.0 3.2e-12 46.6 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family BAH PF01426.13 KEY65178.1 - 1.1e-05 25.2 0.0 2.1e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 KEY65178.1 - 0.0021 17.6 0.9 0.0021 17.6 0.6 1.7 2 0 0 2 2 2 1 PHD-finger FANCL_C PF11793.3 KEY65178.1 - 0.0032 17.3 0.9 0.0082 16.0 0.6 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING-like PF08746.6 KEY65178.1 - 0.023 14.6 0.1 0.067 13.2 0.0 1.8 1 0 0 1 1 1 0 RING-like domain Pribosyl_synth PF14572.1 KEY65179.1 - 9.5e-43 146.0 0.6 1.9e-35 122.3 0.2 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KEY65179.1 - 3.5e-39 133.1 0.1 2.2e-38 130.5 0.0 2.2 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KEY65179.1 - 2.4e-11 43.4 0.1 6.2e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KEY65179.1 - 0.0015 17.7 0.1 0.0024 17.1 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase ATG22 PF11700.3 KEY65180.1 - 9.6e-194 644.2 14.1 1.1e-193 644.0 9.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_2 PF13347.1 KEY65180.1 - 1.5e-05 23.5 24.0 8e-05 21.2 6.3 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein DUF3602 PF12223.3 KEY65181.1 - 3.7e-16 59.2 16.3 5.1e-13 49.2 6.1 2.9 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) CHORD PF04968.7 KEY65182.1 - 6.6e-50 167.2 19.2 3.6e-25 88.0 3.6 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.11 KEY65182.1 - 1.8e-15 57.2 0.1 2.8e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 CS domain DUF836 PF05768.9 KEY65183.1 - 2.7e-13 49.9 0.0 3.1e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 KEY65183.1 - 0.00034 20.5 0.0 0.001 19.0 0.0 1.7 1 1 1 2 2 2 1 Glutaredoxin Thioredoxin_2 PF13098.1 KEY65183.1 - 0.021 14.9 0.0 0.03 14.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain HpcH_HpaI PF03328.9 KEY65184.1 - 3.7e-37 127.3 0.0 4.6e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family SHS2_Rpb7-N PF03876.12 KEY65185.1 - 2.5e-15 56.3 0.0 3.9e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KEY65185.1 - 1.6e-13 50.5 0.0 2.3e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.6 KEY65186.1 - 2.5e-27 94.5 0.0 4.4e-27 93.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) NPL4 PF05021.10 KEY65188.1 - 6.1e-131 436.1 0.0 7.6e-131 435.8 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 KEY65188.1 - 1.9e-68 228.7 0.0 3.4e-68 227.9 0.0 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 KEY65188.1 - 0.0018 18.5 0.0 0.0069 16.6 0.0 1.9 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Sec66 PF09802.4 KEY65189.1 - 5e-79 264.1 0.2 5.7e-79 263.9 0.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF972 PF06156.8 KEY65189.1 - 0.077 13.3 1.5 0.13 12.6 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) FUSC PF04632.7 KEY65189.1 - 0.24 9.8 2.2 0.51 8.7 1.5 1.6 1 1 1 2 2 2 0 Fusaric acid resistance protein family DMPK_coil PF08826.5 KEY65189.1 - 0.26 11.1 4.9 0.48 10.3 0.3 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like SF-assemblin PF06705.6 KEY65189.1 - 0.7 8.9 5.6 1 8.4 2.6 1.9 1 1 1 2 2 2 0 SF-assemblin/beta giardin ORC3_N PF07034.6 KEY65191.1 - 1.3e-36 126.2 2.9 3.6e-36 124.8 2.0 1.8 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus DUF776 PF05604.6 KEY65191.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF776) Ribosomal_L21p PF00829.16 KEY65192.1 - 0.0088 16.1 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Ribosomal_S8e PF01201.17 KEY65193.1 - 1.9e-35 121.8 7.4 1.3e-34 119.1 5.1 2.0 1 1 0 1 1 1 1 Ribosomal protein S8e DUF2390 PF09523.5 KEY65193.1 - 4.6 7.4 6.5 9.8 6.4 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) UQ_con PF00179.21 KEY65194.1 - 1.7e-27 95.5 0.2 5.3e-14 51.8 0.1 3.0 2 1 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEY65194.1 - 0.0017 18.1 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B AAA PF00004.24 KEY65195.1 - 5e-17 62.3 0.0 3e-16 59.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KEY65195.1 - 1.6e-13 50.6 0.0 5.4e-13 48.9 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KEY65195.1 - 6.2e-12 44.9 0.1 2.7e-08 32.9 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 KEY65195.1 - 8.2e-11 41.7 0.0 2.2e-10 40.3 0.0 1.7 2 0 0 2 2 1 1 Replication factor C C-terminal domain RuvB_N PF05496.7 KEY65195.1 - 5.9e-07 28.7 0.1 1.8e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KEY65195.1 - 1.7e-06 28.2 0.0 4.9e-05 23.4 0.0 2.7 2 1 0 2 2 1 1 AAA domain DNA_pol3_delta PF06144.8 KEY65195.1 - 2e-05 24.1 0.1 4.7e-05 22.9 0.0 1.6 2 0 0 2 2 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.1 KEY65195.1 - 2.3e-05 24.0 0.0 5.2e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KEY65195.1 - 2.8e-05 24.1 0.0 0.00047 20.2 0.0 2.6 2 1 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 KEY65195.1 - 4.4e-05 23.3 0.0 9.5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KEY65195.1 - 5.2e-05 22.9 0.0 0.0001 21.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KEY65195.1 - 0.00011 21.3 0.0 0.0049 16.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 KEY65195.1 - 0.00028 19.9 0.0 0.00057 18.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.8 KEY65195.1 - 0.0019 17.1 0.0 0.0032 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 KEY65195.1 - 0.0024 17.2 0.0 0.013 14.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEY65195.1 - 0.0029 18.4 0.0 0.0072 17.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 KEY65195.1 - 0.0029 17.1 0.2 0.026 13.9 0.0 2.4 2 2 0 2 2 2 1 FtsK/SpoIIIE family TIP49 PF06068.8 KEY65195.1 - 0.0032 16.2 0.0 0.36 9.4 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus AAA_5 PF07728.9 KEY65195.1 - 0.0045 16.7 0.1 0.033 13.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KEY65195.1 - 0.0064 16.0 0.0 0.037 13.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 KEY65195.1 - 0.0099 15.4 1.8 0.011 15.2 0.3 1.9 2 1 0 2 2 1 1 AAA domain AAA_28 PF13521.1 KEY65195.1 - 0.018 15.0 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEY65195.1 - 0.025 14.8 0.0 0.078 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KEY65195.1 - 0.026 14.1 0.0 0.12 11.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.18 KEY65195.1 - 0.031 13.0 0.0 1.9 7.2 0.0 2.2 1 1 0 2 2 2 0 SNF2 family N-terminal domain RNA_helicase PF00910.17 KEY65195.1 - 0.032 14.3 0.0 0.09 12.9 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 KEY65195.1 - 0.051 13.0 0.1 0.71 9.2 0.0 2.3 2 1 1 3 3 3 0 AAA-like domain PhoH PF02562.11 KEY65195.1 - 0.072 12.3 1.1 2.5 7.2 0.0 2.7 3 0 0 3 3 3 0 PhoH-like protein AAA_33 PF13671.1 KEY65195.1 - 0.093 12.6 0.0 0.23 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 KEY65195.1 - 0.1 12.3 0.0 0.61 9.8 0.0 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit DUF342 PF03961.8 KEY65196.1 - 9.2 4.5 8.0 0.93 7.8 2.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Sec63 PF02889.11 KEY65197.1 - 7.4e-196 649.5 0.1 1.2e-107 359.8 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KEY65197.1 - 8.8e-56 188.0 0.6 7.6e-32 110.1 0.0 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 KEY65197.1 - 8.4e-17 61.5 0.0 1.6e-08 34.6 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KEY65197.1 - 2.5e-11 43.2 0.0 1.8e-09 37.3 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KEY65197.1 - 8.3e-07 29.2 0.1 0.006 16.7 0.0 3.3 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 KEY65197.1 - 0.00041 19.6 0.0 0.062 12.5 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 KEY65197.1 - 0.00044 19.2 0.0 0.4 9.5 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 KEY65197.1 - 0.00093 18.7 2.8 1 8.7 0.0 4.4 5 1 1 6 6 6 2 AAA-like domain AAA_19 PF13245.1 KEY65197.1 - 0.0097 15.6 0.0 1.5 8.6 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain PWWP PF00855.12 KEY65198.1 - 6e-14 52.0 0.4 3e-13 49.7 0.0 2.5 2 0 0 2 2 2 1 PWWP domain Peptidase_M1 PF01433.15 KEY65199.1 - 1.6e-72 244.7 0.0 2.2e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KEY65199.1 - 2.1e-45 153.8 0.0 3.8e-45 152.9 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KEY65199.1 - 1.2e-17 64.1 0.7 2.2e-17 63.2 0.5 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 KEY65199.1 - 0.18 11.8 2.2 1.3 9.0 1.6 2.4 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Kinesin PF00225.18 KEY65200.1 - 1.6e-111 372.2 0.0 3.3e-111 371.2 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 KEY65200.1 - 5.4e-44 149.2 0.2 1.6e-43 147.7 0.1 1.9 1 0 0 1 1 1 1 Kinesin protein FHA PF00498.21 KEY65200.1 - 3.6e-06 27.0 0.1 3.6e-05 23.7 0.1 2.7 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.3 KEY65200.1 - 6.7e-05 22.8 1.2 0.00013 21.8 0.2 2.2 2 0 0 2 2 2 1 Kinesin protein 1B PH PF00169.24 KEY65200.1 - 0.012 15.7 0.0 0.066 13.4 0.0 2.2 2 1 0 2 2 2 0 PH domain AAA_22 PF13401.1 KEY65200.1 - 0.035 14.2 0.0 0.2 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain HEAT PF02985.17 KEY65202.1 - 4.4e-12 45.0 1.3 0.068 13.2 0.0 5.3 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 KEY65202.1 - 2.4e-07 31.0 0.0 0.002 18.5 0.0 3.0 2 0 0 2 2 2 2 HEAT-like repeat Pkinase_Tyr PF07714.12 KEY65202.1 - 3.6e-07 29.5 0.0 5.9e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KEY65202.1 - 1.1e-06 28.0 0.0 2.3e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain HEAT_2 PF13646.1 KEY65202.1 - 6.2e-06 26.4 0.5 0.00058 20.0 0.1 2.4 1 1 1 2 2 2 2 HEAT repeats Cnd1 PF12717.2 KEY65202.1 - 0.14 11.9 0.0 0.36 10.6 0.0 1.6 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 DUF3439 PF11921.3 KEY65202.1 - 0.41 10.4 6.4 0.86 9.3 4.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pyridoxal_deC PF00282.14 KEY65203.1 - 1.9e-24 85.8 0.0 2.7e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.16 KEY65203.1 - 0.00016 20.7 0.0 0.00033 19.7 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KEY65203.1 - 0.0023 17.1 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cyt-b5 PF00173.23 KEY65204.1 - 2.1e-21 75.4 0.7 2.3e-21 75.3 0.5 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Nuclease_act PF08133.6 KEY65204.1 - 0.0037 16.7 0.1 0.0081 15.6 0.0 1.5 2 0 0 2 2 2 1 Anticodon nuclease activator family V-ATPase_H_C PF11698.3 KEY65204.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H Peptidase_M48 PF01435.13 KEY65205.1 - 5.3e-37 127.5 0.0 7.7e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 UPF0126 PF03458.8 KEY65205.1 - 0.47 10.0 6.4 1 8.9 2.4 2.8 2 1 0 2 2 2 0 UPF0126 domain Methyltransf_23 PF13489.1 KEY65206.1 - 1.7e-14 53.8 0.0 3.3e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY65206.1 - 1.2e-06 29.0 0.0 9.5e-06 26.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY65206.1 - 0.012 16.0 0.0 0.17 12.3 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KEY65206.1 - 0.024 13.7 0.0 0.065 12.3 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEY65206.1 - 0.12 12.6 0.0 0.33 11.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Aconitase PF00330.15 KEY65207.1 - 3.2e-146 487.4 0.0 5.7e-146 486.6 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KEY65207.1 - 6.3e-38 129.8 0.0 9.9e-38 129.2 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 KEY65207.1 - 0.084 11.4 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Nucleopor_Nup85 PF07575.8 KEY65208.1 - 4.8e-12 44.8 0.1 1.7e-11 43.0 0.1 1.8 1 1 0 1 1 1 1 Nup85 Nucleoporin Nic96 PF04097.9 KEY65208.1 - 0.078 11.0 0.3 0.12 10.5 0.2 1.1 1 0 0 1 1 1 0 Nup93/Nic96 SDA1 PF05285.7 KEY65208.1 - 0.97 8.6 29.9 1.9 7.6 20.7 1.4 1 0 0 1 1 1 0 SDA1 CDC27 PF09507.5 KEY65208.1 - 1.4 8.0 16.7 2.1 7.4 11.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SAPS PF04499.10 KEY65208.1 - 7.3 5.1 11.5 14 4.2 8.0 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ADH_N PF08240.7 KEY65209.1 - 1.9e-28 98.3 2.1 5e-28 97.0 1.4 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY65209.1 - 4.9e-20 71.4 0.4 8.1e-20 70.6 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KEY65209.1 - 0.013 14.8 0.2 0.024 14.0 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 KEY65209.1 - 0.096 12.6 0.1 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain HhH-GPD PF00730.20 KEY65210.1 - 2.4e-12 47.0 0.0 1.9e-11 44.2 0.0 2.2 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KEY65210.1 - 7.2e-08 31.7 0.0 1.8e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF2475 PF10629.4 KEY65210.1 - 0.098 12.9 0.2 0.29 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2475) Med3 PF11593.3 KEY65210.1 - 0.28 10.3 1.6 0.36 10.0 1.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Gln-synt_C PF00120.19 KEY65211.1 - 1.7e-59 201.1 0.0 2.1e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KEY65211.1 - 1.1e-19 69.7 0.0 2e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain CorA PF01544.13 KEY65212.1 - 0.0039 16.2 0.1 0.0039 16.2 0.0 1.7 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein PgaD PF13994.1 KEY65212.1 - 0.004 16.6 0.1 0.0061 16.0 0.1 1.4 1 0 0 1 1 1 1 PgaD-like protein BatD PF13584.1 KEY65212.1 - 0.047 12.2 0.0 0.058 11.9 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance LMBR1 PF04791.11 KEY65213.1 - 2.5e-28 98.9 9.6 5.1e-28 97.8 6.6 1.4 1 1 0 1 1 1 1 LMBR1-like membrane protein SAS4 PF15460.1 KEY65213.1 - 0.035 13.9 0.1 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 DUF885 PF05960.6 KEY65213.1 - 0.15 11.1 0.1 0.29 10.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Hat1_N PF10394.4 KEY65214.1 - 1.7e-38 132.2 0.0 2.7e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus CTK3 PF12243.3 KEY65215.1 - 3e-55 185.6 0.2 4e-55 185.2 0.1 1.1 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 KEY65215.1 - 5.9e-16 58.2 8.0 1.5e-15 56.9 5.6 1.8 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus DUF664 PF04978.7 KEY65215.1 - 0.37 11.0 5.0 0.3 11.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF664) KMP11 PF03037.11 KEY65215.1 - 1.9 9.0 5.0 1.6 9.3 0.9 2.3 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 Ribosomal_L12 PF00542.14 KEY65216.1 - 2.5e-19 69.0 5.5 1.6e-18 66.4 2.4 2.3 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain AAA_5 PF07728.9 KEY65217.1 - 2.6e-124 409.5 0.0 6.5e-22 77.7 0.0 9.6 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KEY65217.1 - 3.1e-27 94.7 0.0 7.8e-10 38.4 0.0 6.8 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KEY65217.1 - 8.6e-27 93.9 0.1 9.1e-05 22.6 0.0 6.9 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEY65217.1 - 1.7e-22 80.4 8.4 0.00018 22.3 0.0 8.0 8 0 0 8 8 6 5 AAA domain AAA_22 PF13401.1 KEY65217.1 - 6.1e-20 71.7 4.9 0.011 15.8 0.0 9.0 9 1 0 9 9 6 5 AAA domain AAA_16 PF13191.1 KEY65217.1 - 5.3e-19 68.9 23.6 0.00061 19.8 0.0 9.9 9 0 0 9 9 7 4 AAA ATPase domain AAA_33 PF13671.1 KEY65217.1 - 8.6e-19 67.8 0.0 0.013 15.4 0.0 6.9 6 0 0 6 6 6 4 AAA domain Sigma54_activat PF00158.21 KEY65217.1 - 2.7e-17 62.7 0.0 0.036 13.5 0.0 5.6 5 0 0 5 5 5 5 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KEY65217.1 - 1.7e-16 60.5 0.1 0.00062 19.8 0.0 6.7 6 0 0 6 6 5 2 Sigma-54 interaction domain AAA_14 PF13173.1 KEY65217.1 - 1.8e-16 60.2 0.0 0.00021 21.1 0.0 6.4 6 0 0 6 6 5 2 AAA domain AAA_18 PF13238.1 KEY65217.1 - 8.9e-16 58.3 9.1 0.0015 18.8 0.0 6.9 7 0 0 7 7 5 3 AAA domain T2SE PF00437.15 KEY65217.1 - 1.7e-15 56.6 0.4 0.064 12.1 0.0 5.5 5 0 0 5 5 5 5 Type II/IV secretion system protein AAA_19 PF13245.1 KEY65217.1 - 2.4e-15 56.0 6.4 0.012 15.3 0.1 6.7 6 0 0 6 6 6 4 Part of AAA domain UPF0079 PF02367.12 KEY65217.1 - 6.7e-13 48.3 2.8 0.02 14.5 0.0 5.4 5 0 0 5 5 5 3 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 KEY65217.1 - 3e-11 43.4 2.9 0.17 12.0 0.0 6.6 6 0 0 6 6 6 2 RNA helicase RuvB_N PF05496.7 KEY65217.1 - 3.4e-11 42.6 0.9 0.031 13.3 0.0 6.0 6 0 0 6 6 6 3 Holliday junction DNA helicase ruvB N-terminus DUF258 PF03193.11 KEY65217.1 - 1.1e-10 40.8 1.1 0.11 11.6 0.1 5.5 6 0 0 6 6 5 3 Protein of unknown function, DUF258 NACHT PF05729.7 KEY65217.1 - 6.1e-10 39.0 7.2 0.077 12.6 0.1 5.5 5 0 0 5 5 4 3 NACHT domain MobB PF03205.9 KEY65217.1 - 1.7e-09 37.4 1.0 0.32 10.6 0.0 5.7 5 0 0 5 5 5 2 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 KEY65217.1 - 6.4e-09 35.4 0.1 0.068 12.5 0.0 5.5 6 0 0 6 6 6 2 IstB-like ATP binding protein AAA_29 PF13555.1 KEY65217.1 - 6.9e-09 35.1 0.1 0.44 10.1 0.0 5.9 5 0 0 5 5 5 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 KEY65217.1 - 8.9e-09 35.3 0.0 0.35 10.5 0.0 6.3 6 0 0 6 6 6 1 Archaeal ATPase AAA_25 PF13481.1 KEY65217.1 - 1.1e-08 34.7 0.5 0.34 10.2 0.0 4.7 4 0 0 4 4 4 3 AAA domain Mg_chelatase PF01078.16 KEY65217.1 - 6.2e-08 32.0 0.7 5 6.2 0.0 6.8 7 0 0 7 7 7 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KEY65217.1 - 8.9e-07 29.0 13.5 0.29 11.0 0.0 7.0 7 0 0 7 7 6 2 AAA domain PduV-EutP PF10662.4 KEY65217.1 - 3.5e-06 26.5 3.4 0.071 12.6 0.0 4.7 5 0 0 5 5 5 2 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 KEY65217.1 - 3.8e-06 26.4 5.0 0.56 9.6 0.1 5.2 5 0 0 5 5 5 2 SRP54-type protein, GTPase domain NTPase_1 PF03266.10 KEY65217.1 - 4.3e-06 26.5 6.2 0.7 9.5 0.1 5.6 5 0 0 5 5 5 2 NTPase ABC_tran PF00005.22 KEY65217.1 - 6.7e-06 26.4 13.9 0.054 13.7 0.0 6.6 6 1 0 6 6 5 2 ABC transporter Rad17 PF03215.10 KEY65217.1 - 3.7e-05 22.6 0.4 0.93 8.0 0.0 4.6 5 0 0 5 5 5 1 Rad17 cell cycle checkpoint protein FtsK_SpoIIIE PF01580.13 KEY65217.1 - 5.4e-05 22.7 2.0 6.6 6.1 0.0 5.1 5 0 0 5 5 4 0 FtsK/SpoIIIE family Miro PF08477.8 KEY65217.1 - 5.5e-05 23.6 13.3 6.8 7.2 0.0 6.3 7 0 0 7 7 5 0 Miro-like protein AAA_7 PF12775.2 KEY65217.1 - 0.00092 18.3 0.8 8.5 5.3 0.0 4.1 4 0 0 4 4 4 0 P-loop containing dynein motor region D3 KaiC PF06745.8 KEY65217.1 - 0.001 18.2 0.0 11 5.0 0.0 4.5 4 0 0 4 4 4 0 KaiC Viral_helicase1 PF01443.13 KEY65217.1 - 0.0015 18.1 0.2 21 4.5 0.0 4.7 5 0 0 5 5 4 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.18 KEY65217.1 - 0.0023 17.8 0.4 58 3.6 0.0 4.7 4 0 0 4 4 4 0 50S ribosome-binding GTPase PhoH PF02562.11 KEY65217.1 - 0.0032 16.7 1.6 9.7 5.3 0.0 4.4 4 0 0 4 4 4 0 PhoH-like protein AAA_6 PF12774.2 KEY65217.1 - 0.0038 16.8 0.0 19 4.6 0.0 4.8 5 0 0 5 5 4 0 Hydrolytic ATP binding site of dynein motor region D1 PRK PF00485.13 KEY65217.1 - 0.0043 16.6 0.7 14 5.1 0.0 4.1 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family Y_phosphatase PF00102.22 KEY65217.1 - 0.0098 15.2 0.2 13 5.0 0.0 3.9 4 0 0 4 4 4 0 Protein-tyrosine phosphatase ATP_bind_1 PF03029.12 KEY65217.1 - 0.22 11.0 8.7 20 4.6 0.0 4.8 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein CbiA PF01656.18 KEY65217.1 - 0.3 10.4 4.7 2.9 7.2 0.0 3.5 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Isochorismatase PF00857.15 KEY65218.1 - 2.9e-20 72.9 0.1 4.4e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family DUF919 PF06034.6 KEY65219.1 - 0.18 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Lipase_GDSL PF00657.17 KEY65220.1 - 4.9e-19 69.0 0.0 5.8e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KEY65220.1 - 2.8e-18 66.6 0.0 3.3e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family BP28CT PF08146.7 KEY65221.1 - 2.1e-41 141.2 0.1 1.1e-40 138.8 0.0 2.4 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 KEY65221.1 - 1.9e-22 79.4 12.5 6.4e-22 77.7 0.2 5.1 5 0 0 5 5 5 2 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 KEY65221.1 - 2.6e-08 33.2 9.6 0.0034 17.3 0.0 6.9 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 KEY65221.1 - 7.2e-06 26.2 18.7 0.17 12.1 0.0 7.1 6 1 1 7 7 7 4 HEAT repeats HK PF02110.10 KEY65222.1 - 2.1e-72 243.2 4.4 5.9e-72 241.7 3.0 1.8 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 KEY65222.1 - 1.8e-40 138.0 1.4 3.2e-40 137.1 1.0 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Pyr_redox_2 PF07992.9 KEY65222.1 - 4.2e-32 111.6 3.2 4.6e-32 111.5 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY65222.1 - 1.1e-12 48.2 0.0 3.6e-10 40.1 0.0 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY65222.1 - 2.7e-05 24.3 0.0 0.019 15.0 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY65222.1 - 0.038 14.0 0.0 18 5.4 0.0 3.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Aminotran_1_2 PF00155.16 KEY65223.1 - 2.7e-83 279.8 0.0 3.4e-83 279.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KEY65223.1 - 2.5e-05 23.2 0.0 4.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KEY65223.1 - 2.7e-05 22.6 0.0 4.1e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF3405 PF11885.3 KEY65223.1 - 0.00037 18.8 0.1 0.00055 18.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DegT_DnrJ_EryC1 PF01041.12 KEY65223.1 - 0.027 13.5 0.1 0.052 12.5 0.1 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family RVT_1 PF00078.22 KEY65224.1 - 1.9e-31 109.1 0.0 3.8e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APG6 PF04111.7 KEY65225.1 - 0.0097 14.9 11.4 0.013 14.5 7.9 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 UCH PF00443.24 KEY65225.1 - 0.067 12.2 3.9 0.068 12.2 2.7 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase CDC37_N PF03234.9 KEY65225.1 - 0.081 13.2 8.6 0.015 15.6 2.8 1.8 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding DUF342 PF03961.8 KEY65225.1 - 0.1 10.9 7.9 0.11 10.8 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Filament PF00038.16 KEY65225.1 - 0.31 10.4 16.1 0.5 9.7 11.2 1.3 1 0 0 1 1 1 0 Intermediate filament protein PEP-utilisers_N PF05524.8 KEY65225.1 - 0.34 10.6 5.0 0.11 12.3 1.3 1.8 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal PHTB1_N PF14727.1 KEY65225.1 - 0.39 9.6 5.0 0.53 9.1 3.4 1.2 1 0 0 1 1 1 0 PTHB1 N-terminus SAB PF04382.8 KEY65225.1 - 0.52 10.0 3.5 1.9 8.2 0.0 2.7 2 1 0 3 3 3 0 SAB domain DUF948 PF06103.6 KEY65225.1 - 0.98 9.3 3.2 3 7.7 2.0 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) RPA_interact_M PF14767.1 KEY65225.1 - 1.3 9.7 9.2 2.7 8.8 6.4 1.6 1 0 0 1 1 1 0 Replication protein A interacting middle AAA_13 PF13166.1 KEY65225.1 - 1.9 6.8 11.3 0.75 8.1 6.3 1.3 1 1 0 1 1 1 0 AAA domain Ly49 PF08391.5 KEY65225.1 - 2.6 8.2 8.2 3.7 7.6 5.7 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region UPF0242 PF06785.6 KEY65225.1 - 2.7 6.5 9.5 3.5 6.2 6.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Cep57_CLD_2 PF14197.1 KEY65225.1 - 5.4 7.0 14.9 11 6.0 10.3 1.6 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 zf-PARP PF00645.13 KEY65229.1 - 1.1e-17 64.0 0.4 2.3e-17 62.9 0.2 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Utp14 PF04615.8 KEY65229.1 - 0.15 10.2 41.6 0.18 9.9 28.8 1.0 1 0 0 1 1 1 0 Utp14 protein PI3_PI4_kinase PF00454.22 KEY65230.1 - 1.5e-47 162.0 0.0 2.8e-47 161.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KEY65230.1 - 1.8e-33 116.0 3.6 3.1e-33 115.2 1.7 2.0 2 0 0 2 2 2 1 FAT domain UME PF08064.8 KEY65230.1 - 3e-25 88.2 0.6 2.8e-24 85.1 0.0 3.1 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.15 KEY65230.1 - 7.7e-16 57.2 0.0 1.6e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 FATC domain HSP70 PF00012.15 KEY65230.1 - 3.3e-07 28.6 0.0 1.9e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Hsp70 protein BcrAD_BadFG PF01869.15 KEY65230.1 - 0.079 12.2 0.1 0.15 11.2 0.1 1.4 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family TPR_19 PF14559.1 KEY65230.1 - 0.1 12.9 0.1 0.1 12.9 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat IncA PF04156.9 KEY65231.1 - 0.00092 18.8 8.6 0.0015 18.1 6.0 1.3 1 0 0 1 1 1 1 IncA protein KLRAQ PF10205.4 KEY65231.1 - 0.0055 16.7 9.1 0.01 15.8 6.3 1.4 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein CENP-F_leu_zip PF10473.4 KEY65231.1 - 0.011 15.5 10.9 0.022 14.5 7.5 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HhH-GPD PF00730.20 KEY65231.1 - 0.05 13.8 0.0 0.36 11.1 0.0 2.1 2 0 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein ADIP PF11559.3 KEY65231.1 - 0.05 13.5 13.2 0.08 12.8 9.1 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 KEY65231.1 - 0.052 11.4 1.1 0.061 11.1 0.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HrpB7 PF09486.5 KEY65231.1 - 0.057 13.3 5.7 0.087 12.7 3.6 1.6 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF3373 PF11853.3 KEY65231.1 - 0.074 11.5 0.2 0.093 11.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF3037 PF11236.3 KEY65231.1 - 0.087 12.8 0.5 0.21 11.6 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) Spc7 PF08317.6 KEY65231.1 - 0.092 11.3 10.8 0.14 10.8 7.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 KEY65231.1 - 0.28 10.0 9.2 0.52 9.2 6.4 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fmp27_WPPW PF10359.4 KEY65231.1 - 0.38 9.1 6.2 0.52 8.6 4.3 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain GLE1 PF07817.8 KEY65231.1 - 0.47 9.3 3.9 0.74 8.6 2.7 1.2 1 0 0 1 1 1 0 GLE1-like protein Tnp_P_element PF12017.3 KEY65231.1 - 0.51 9.5 4.3 0.89 8.7 3.0 1.3 1 0 0 1 1 1 0 Transposase protein FemAB PF02388.11 KEY65231.1 - 0.53 8.9 6.6 0.76 8.3 4.5 1.1 1 0 0 1 1 1 0 FemAB family AAA_23 PF13476.1 KEY65231.1 - 0.64 10.3 10.3 1 9.6 7.1 1.2 1 0 0 1 1 1 0 AAA domain DASH_Hsk3 PF08227.6 KEY65231.1 - 0.64 10.2 4.0 1.5 9.0 2.8 1.6 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like Pox_A_type_inc PF04508.7 KEY65231.1 - 1.6 8.7 3.9 7.7 6.5 0.2 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF972 PF06156.8 KEY65231.1 - 2.1 8.7 6.5 3.9 7.8 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) APG6 PF04111.7 KEY65231.1 - 2.9 6.8 12.7 4.1 6.3 8.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc24 PF08286.6 KEY65231.1 - 3.8 7.2 10.8 1.3 8.6 5.4 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 AIG2 PF06094.7 KEY65232.1 - 1.3e-09 38.4 0.0 2.3e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 KEY65232.1 - 6.2e-05 23.0 0.0 0.016 15.3 0.0 2.5 2 0 0 2 2 2 1 AIG2-like family PLRV_ORF5 PF01690.12 KEY65232.1 - 0.00066 18.9 14.6 0.001 18.3 10.1 1.3 1 0 0 1 1 1 1 Potato leaf roll virus readthrough protein DUF2360 PF10152.4 KEY65232.1 - 0.51 10.6 8.9 0.45 10.8 1.7 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) FAM75 PF14650.1 KEY65232.1 - 6.6 6.0 13.3 11 5.3 9.2 1.3 1 0 0 1 1 1 0 FAM75 family Pex14_N PF04695.8 KEY65232.1 - 7.2 6.6 8.7 5 7.1 2.1 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Amidoligase_2 PF12224.3 KEY65233.1 - 5e-23 82.0 0.0 9.9e-23 81.0 0.0 1.5 2 0 0 2 2 2 1 Putative amidoligase enzyme CPSase_L_D2 PF02786.12 KEY65234.1 - 1.2e-73 246.9 0.0 2.6e-73 245.8 0.0 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KEY65234.1 - 1.7e-34 117.9 0.0 3.4e-34 117.0 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KEY65234.1 - 3.4e-33 114.0 0.0 6.6e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KEY65234.1 - 2.7e-19 69.6 0.1 8.2e-19 68.0 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KEY65234.1 - 2.8e-16 58.9 1.4 8.8e-16 57.3 1.0 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KEY65234.1 - 1e-15 57.3 0.0 1.8e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 KEY65234.1 - 4.2e-10 39.1 0.2 5.9e-05 22.6 0.0 2.8 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 KEY65234.1 - 1.1e-08 34.7 0.0 2.6e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KEY65234.1 - 4.8e-08 32.5 0.0 1.1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 KEY65234.1 - 0.00011 22.5 0.0 0.41 10.9 0.0 2.9 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 KEY65234.1 - 0.00031 20.6 0.0 0.00069 19.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 KEY65234.1 - 0.002 17.4 0.1 0.16 11.2 0.0 2.5 1 1 1 2 2 2 1 HlyD family secretion protein GCV_H PF01597.14 KEY65234.1 - 0.069 12.8 0.4 0.69 9.6 0.1 2.4 2 0 0 2 2 2 0 Glycine cleavage H-protein HlyD_2 PF12700.2 KEY65234.1 - 0.1 11.7 0.1 1.5 7.8 0.0 2.1 1 1 1 2 2 2 0 HlyD family secretion protein Pyridox_oxidase PF01243.15 KEY65235.1 - 8.3e-11 41.7 0.0 1.6e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Mem_trans PF03547.13 KEY65236.1 - 2.4e-53 180.8 0.3 7.2e-53 179.2 0.2 1.6 1 1 0 1 1 1 1 Membrane transport protein Pkinase PF00069.20 KEY65237.1 - 1.8e-50 171.5 0.0 1.2e-47 162.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEY65237.1 - 7.9e-31 107.0 0.0 1.1e-29 103.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 KEY65237.1 - 0.00022 20.1 0.1 0.00036 19.4 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 KEY65237.1 - 0.00078 18.4 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 KEY65237.1 - 0.16 10.7 0.1 0.28 9.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SUR7 PF06687.7 KEY65238.1 - 1.6e-30 106.3 6.6 2e-30 105.9 4.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KEY65238.1 - 0.00066 19.4 15.9 0.00066 19.4 11.0 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction PGG PF13962.1 KEY65238.1 - 0.59 9.7 10.7 3.5 7.2 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function DUF2207 PF09972.4 KEY65238.1 - 3 6.3 5.5 0.21 10.1 0.3 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4064 PF13273.1 KEY65238.1 - 3.7 7.7 12.7 36 4.5 5.5 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) BPL_LplA_LipB PF03099.14 KEY65239.1 - 6.1e-08 32.7 0.0 1e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ALO PF04030.9 KEY65240.1 - 4.3e-87 291.9 0.1 5.5e-87 291.6 0.1 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 KEY65240.1 - 1.7e-30 105.2 0.0 2.5e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain EFG_IV PF03764.13 KEY65240.1 - 0.049 13.2 0.0 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 Elongation factor G, domain IV ABC_tran PF00005.22 KEY65241.1 - 3.2e-43 147.3 0.0 7.4e-23 81.3 0.0 2.7 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEY65241.1 - 3.1e-18 66.1 35.8 2e-17 63.4 10.9 2.5 3 0 0 3 3 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KEY65241.1 - 1.6e-12 48.0 0.6 0.13 12.2 0.1 4.3 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 KEY65241.1 - 5.1e-11 42.2 1.8 0.0044 16.2 0.0 4.1 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KEY65241.1 - 3.1e-08 33.8 3.1 0.0034 17.3 0.1 3.5 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 KEY65241.1 - 3.4e-07 29.6 0.5 0.035 13.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KEY65241.1 - 1e-05 25.0 0.1 0.021 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KEY65241.1 - 2.7e-05 24.6 0.2 0.32 11.5 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 KEY65241.1 - 3.9e-05 22.8 1.2 0.15 11.2 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KEY65241.1 - 0.00027 20.8 0.1 0.36 10.7 0.0 3.0 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 KEY65241.1 - 0.00059 19.7 2.0 0.62 10.0 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase MobB PF03205.9 KEY65241.1 - 0.0011 18.6 1.6 0.68 9.6 0.0 2.7 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KEY65241.1 - 0.0012 18.4 1.4 1.2 8.4 0.3 2.5 2 0 0 2 2 2 2 AAA-like domain FtsK_SpoIIIE PF01580.13 KEY65241.1 - 0.0012 18.3 0.1 1.2 8.5 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_17 PF13207.1 KEY65241.1 - 0.0016 19.2 0.3 1.9 9.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 KEY65241.1 - 0.0024 17.7 3.9 0.041 13.6 0.1 2.4 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.12 KEY65241.1 - 0.0039 17.0 1.0 2.4 7.9 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_23 PF13476.1 KEY65241.1 - 0.0042 17.4 0.0 0.26 11.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEY65241.1 - 0.0043 17.1 0.5 4.6 7.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA PF00004.24 KEY65241.1 - 0.0076 16.4 0.0 0.84 9.8 0.0 3.5 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KEY65241.1 - 0.0088 15.7 0.6 0.68 9.5 0.0 2.9 3 0 0 3 3 2 1 NACHT domain DUF815 PF05673.8 KEY65241.1 - 0.016 14.1 0.1 2.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 KEY65241.1 - 0.019 14.0 0.5 3.2 6.8 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin Arch_ATPase PF01637.13 KEY65241.1 - 0.038 13.7 0.3 5.8 6.5 0.0 2.7 3 0 0 3 3 2 0 Archaeal ATPase AAA_18 PF13238.1 KEY65241.1 - 0.04 14.2 0.1 4.1 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KEY65241.1 - 0.045 13.3 0.4 1 8.8 0.1 2.8 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 KEY65241.1 - 0.082 12.6 0.0 11 5.6 0.0 2.3 2 0 0 2 2 2 0 NTPase ATP-synt_ab PF00006.20 KEY65241.1 - 0.1 12.1 0.3 14 5.1 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Zot PF05707.7 KEY65241.1 - 0.13 11.6 0.0 5.8 6.3 0.0 3.0 4 0 0 4 4 3 0 Zonular occludens toxin (Zot) RNA_helicase PF00910.17 KEY65241.1 - 0.22 11.7 0.1 36 4.5 0.0 3.0 3 0 0 3 3 3 0 RNA helicase NB-ARC PF00931.17 KEY65241.1 - 0.32 9.8 1.0 16 4.2 0.2 2.8 2 1 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.1 KEY65241.1 - 0.4 9.6 0.0 0.95 8.4 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.14 KEY65241.1 - 0.53 9.7 1.8 9.4 5.6 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF3433 PF11915.3 KEY65245.1 - 1.2e-30 105.5 21.2 1.3e-28 98.9 1.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) WD40 PF00400.27 KEY65246.1 - 6.8e-31 105.0 4.5 4e-12 45.5 0.1 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat PFU PF09070.6 KEY65247.1 - 3e-43 146.5 0.6 5.4e-43 145.6 0.4 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 KEY65247.1 - 6.2e-43 146.5 0.0 9.6e-43 145.8 0.0 1.3 1 0 0 1 1 1 1 PUL domain WD40 PF00400.27 KEY65247.1 - 2.7e-38 128.4 10.5 9.6e-07 28.4 0.1 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat SRR1 PF07985.7 KEY65249.1 - 0.00014 21.7 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 SRR1 Glyco_hydro_17 PF00332.13 KEY65250.1 - 2.2e-10 40.0 1.3 2.2e-07 30.2 0.2 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Gly-zipper_YMGG PF13441.1 KEY65250.1 - 0.00046 19.6 3.6 0.00046 19.6 2.5 2.7 3 1 0 3 3 3 1 YMGG-like Gly-zipper Na_H_antiport_2 PF13726.1 KEY65250.1 - 0.026 14.4 0.6 0.055 13.3 0.4 1.4 1 0 0 1 1 1 0 Na+-H+ antiporter family DUF3169 PF11368.3 KEY65250.1 - 0.026 13.7 0.1 0.04 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Herpes_US9 PF06072.6 KEY65250.1 - 0.029 14.1 0.3 0.063 13.1 0.2 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Fungal_trans_2 PF11951.3 KEY65252.1 - 5.7e-08 31.7 1.0 6e-05 21.8 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain AAA_12 PF13087.1 KEY65253.1 - 1.9e-32 112.2 0.0 5.3e-32 110.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KEY65253.1 - 3.9e-22 78.9 1.9 5.9e-21 75.1 1.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEY65253.1 - 1.5e-10 40.6 0.1 4.2e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KEY65253.1 - 9.1e-09 35.1 0.0 4.2e-06 26.4 0.0 2.7 3 0 0 3 3 3 2 AAA domain PhoH PF02562.11 KEY65253.1 - 0.0013 17.9 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein Viral_helicase1 PF01443.13 KEY65253.1 - 0.0027 17.2 0.0 0.42 10.1 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 KEY65253.1 - 0.0053 15.7 0.1 0.14 11.0 0.0 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 KEY65253.1 - 0.0056 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KEY65253.1 - 0.034 14.2 0.0 0.41 10.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain WD40 PF00400.27 KEY65254.1 - 6.3e-14 51.2 0.8 0.054 13.4 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF605 PF04652.11 KEY65256.1 - 1.7 7.9 9.7 2 7.7 6.7 1.1 1 0 0 1 1 1 0 Vta1 like Methyltransf_PK PF05891.7 KEY65257.1 - 2.8e-73 245.8 0.0 3.2e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Snf7 PF03357.16 KEY65258.1 - 4.2e-07 29.5 26.5 4.2e-07 29.5 18.4 1.4 1 1 0 1 1 1 1 Snf7 Ist1 PF03398.9 KEY65258.1 - 0.0058 16.0 6.5 0.013 14.8 4.5 1.6 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway ASL_C PF08328.6 KEY65258.1 - 0.33 10.7 7.5 0.25 11.1 2.8 2.2 1 1 0 2 2 2 0 Adenylosuccinate lyase C-terminal DUF1451 PF07295.6 KEY65258.1 - 1.1 9.0 11.5 0.65 9.7 3.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) Dynactin_p62 PF05502.8 KEY65258.1 - 1.7 7.3 12.3 2 7.0 8.5 1.1 1 0 0 1 1 1 0 Dynactin p62 family DSHCT PF08148.7 KEY65259.1 - 5e-60 201.8 0.4 9.7e-60 200.8 0.3 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KEY65259.1 - 3.7e-20 72.0 0.0 9.4e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 KEY65259.1 - 2.1e-06 27.1 0.8 1.9e-05 23.9 0.6 2.2 1 1 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 KEY65259.1 - 4.6e-06 26.3 0.7 1.1e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Cut8_C PF08559.5 KEY65259.1 - 0.0095 15.7 0.1 0.028 14.2 0.0 1.8 2 0 0 2 2 2 1 Cut8 six-helix bundle Ribosomal_L9_N PF01281.14 KEY65259.1 - 0.15 11.2 0.0 0.37 10.0 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L9, N-terminal domain Transket_pyr PF02779.19 KEY65260.1 - 1.9e-46 157.7 0.0 2.6e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KEY65260.1 - 3.8e-35 120.5 0.0 9.8e-35 119.1 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Aminotran_5 PF00266.14 KEY65260.1 - 0.051 12.3 0.0 0.11 11.1 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class-V Sterol_MT_C PF08498.5 KEY65261.1 - 1.7e-28 98.3 0.2 2.7e-28 97.6 0.1 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 KEY65261.1 - 1.8e-21 76.3 0.0 3.4e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY65261.1 - 4e-18 65.4 0.0 6.4e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY65261.1 - 9.5e-14 51.5 0.0 2e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY65261.1 - 1.4e-13 50.8 0.1 2.3e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KEY65261.1 - 1.9e-11 43.5 0.1 2.7e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 KEY65261.1 - 8.8e-11 42.3 0.0 2.1e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY65261.1 - 1.2e-10 40.9 0.0 2e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KEY65261.1 - 1.3e-10 41.5 0.0 3.5e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY65261.1 - 8.5e-10 38.6 0.0 2.4e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 KEY65261.1 - 2.7e-05 23.7 0.0 4.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 KEY65261.1 - 7.2e-05 22.2 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KEY65261.1 - 0.00049 19.6 0.0 0.00081 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 KEY65261.1 - 0.00081 18.4 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.8 KEY65261.1 - 0.0014 17.7 0.0 0.0036 16.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 KEY65261.1 - 0.0029 17.0 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.11 KEY65261.1 - 0.0085 14.4 0.0 0.012 13.9 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.1 KEY65261.1 - 0.027 15.2 0.1 0.08 13.7 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 KEY65261.1 - 0.03 13.5 0.4 0.067 12.3 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase TehB PF03848.9 KEY65261.1 - 0.032 13.3 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 KEY65261.1 - 0.051 13.2 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RRM_5 PF13893.1 KEY65262.1 - 1.7e-09 37.3 0.0 3.1e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEY65262.1 - 3.8e-09 36.0 0.0 6.9e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY65262.1 - 1.1e-05 25.3 0.0 2.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEY65262.1 - 0.0021 17.8 0.0 0.005 16.5 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KEY65262.1 - 0.026 14.3 0.2 0.069 13.0 0.0 1.7 2 0 0 2 2 2 0 RNA binding motif Complex1_LYR PF05347.10 KEY65263.1 - 0.0023 17.6 0.1 0.0038 16.9 0.1 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KEY65263.1 - 0.0085 16.2 0.0 0.01 16.0 0.0 1.3 1 1 0 1 1 1 1 Complex1_LYR-like DUF4266 PF14086.1 KEY65263.1 - 0.041 14.3 0.9 0.074 13.5 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) DnaJ PF00226.26 KEY65264.1 - 8.1e-21 73.5 3.2 8.1e-21 73.5 2.2 2.6 2 1 0 2 2 2 1 DnaJ domain Ald_Xan_dh_C2 PF02738.13 KEY65264.1 - 0.48 8.6 9.3 0.47 8.7 2.9 2.5 3 0 0 3 3 3 0 Molybdopterin-binding domain of aldehyde dehydrogenase ABC_membrane PF00664.18 KEY65265.1 - 1.4e-74 250.9 35.6 2.4e-37 128.8 8.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KEY65265.1 - 1.8e-64 216.1 0.0 7.4e-32 110.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KEY65265.1 - 4.2e-12 45.7 4.4 7e-05 22.1 0.0 4.0 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEY65265.1 - 3.6e-11 43.5 0.0 0.25 11.2 0.0 4.4 4 0 0 4 4 4 4 AAA domain AAA_29 PF13555.1 KEY65265.1 - 2.3e-09 36.6 0.8 0.00053 19.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KEY65265.1 - 5.2e-09 36.3 2.1 2.1e-05 24.6 0.2 2.6 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KEY65265.1 - 9e-07 28.2 0.0 0.013 14.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEY65265.1 - 9.3e-07 29.0 0.9 0.065 13.3 0.1 3.8 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KEY65265.1 - 3e-06 26.0 3.3 0.023 13.3 0.0 2.9 4 0 0 4 4 4 2 Predicted ATPase of the ABC class SbcCD_C PF13558.1 KEY65265.1 - 1.2e-05 25.0 1.8 0.21 11.5 0.1 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 KEY65265.1 - 2.1e-05 25.3 0.0 0.16 12.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KEY65265.1 - 6.2e-05 23.4 0.0 0.37 11.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain G-alpha PF00503.15 KEY65265.1 - 0.00016 20.4 0.0 0.06 12.0 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_33 PF13671.1 KEY65265.1 - 0.00034 20.5 0.0 0.65 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KEY65265.1 - 0.00052 19.9 0.0 2 8.3 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 KEY65265.1 - 0.0025 17.2 0.2 2.5 7.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.1 KEY65265.1 - 0.0031 17.5 0.0 0.93 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KEY65265.1 - 0.0046 16.8 0.0 1.3 8.9 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase APS_kinase PF01583.15 KEY65265.1 - 0.0072 15.9 0.0 0.86 9.2 0.0 2.8 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_18 PF13238.1 KEY65265.1 - 0.01 16.1 0.0 4.1 7.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain MobB PF03205.9 KEY65265.1 - 0.011 15.4 0.2 2.2 7.9 0.0 3.2 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 KEY65265.1 - 0.015 15.0 0.1 11 5.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KEY65265.1 - 0.027 13.5 1.2 1.3 8.0 0.0 3.3 4 0 0 4 4 4 0 Zeta toxin DUF87 PF01935.12 KEY65265.1 - 0.041 13.6 0.0 2.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF815 PF05673.8 KEY65265.1 - 0.084 11.7 0.0 4.3 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 KEY65265.1 - 0.14 12.3 0.0 5 7.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.1 KEY65265.1 - 0.41 9.6 0.0 25 3.7 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_10 PF12846.2 KEY65265.1 - 0.64 9.3 6.0 11 5.3 0.1 3.8 4 0 0 4 4 4 0 AAA-like domain Fungal_trans PF04082.13 KEY65266.1 - 5.3e-14 51.7 0.1 3.3e-12 45.8 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain zf-C2H2_jaz PF12171.3 KEY65267.1 - 3.6e-05 23.7 3.4 6e-05 23.0 2.4 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEY65267.1 - 0.00097 19.2 0.9 0.0015 18.6 0.6 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KEY65267.1 - 0.0058 16.8 0.2 0.01 16.0 0.1 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY65267.1 - 0.02 15.2 1.0 0.035 14.4 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 KEY65267.1 - 0.07 13.2 0.9 0.1 12.7 0.6 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 KEY65267.1 - 0.22 11.2 1.8 0.37 10.4 1.2 1.3 1 0 0 1 1 1 0 DBF zinc finger DUF3729 PF12526.3 KEY65267.1 - 3.1 9.1 6.6 0.26 12.6 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) DUF1691 PF07950.6 KEY65268.1 - 2.3e-42 143.3 4.9 1.8e-26 92.2 0.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) RskA PF10099.4 KEY65268.1 - 0.06 13.0 2.0 0.083 12.6 0.2 2.0 2 0 0 2 2 2 0 Anti-sigma-K factor rskA F-box-like PF12937.2 KEY65269.1 - 1e-08 34.7 0.1 2.1e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEY65269.1 - 1.4e-08 34.1 0.3 3e-08 33.1 0.2 1.6 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 KEY65269.1 - 0.18 11.7 2.4 0.68 9.9 0.1 3.1 3 1 0 3 3 3 0 WD domain, G-beta repeat SWIRM PF04433.12 KEY65270.1 - 3e-15 56.1 0.1 4.7e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 SWIRM domain adh_short PF00106.20 KEY65271.1 - 2.3e-17 63.4 2.5 2.3e-17 63.4 1.7 5.9 5 1 0 5 5 5 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY65271.1 - 1.3e-16 61.1 0.4 6.1e-16 58.9 0.0 2.4 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase GRIP PF01465.15 KEY65271.1 - 1.8e-12 46.5 0.2 3.9e-12 45.4 0.1 1.6 1 0 0 1 1 1 1 GRIP domain KR PF08659.5 KEY65271.1 - 1.3e-05 24.8 0.2 1.3e-05 24.8 0.1 5.1 5 0 0 5 5 5 1 KR domain IncA PF04156.9 KEY65271.1 - 3.8e-05 23.3 163.2 7.3e-05 22.4 10.8 8.3 2 2 5 7 7 6 4 IncA protein Shikimate_DH PF01488.15 KEY65271.1 - 0.00018 21.5 0.1 0.0011 19.0 0.1 2.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Phage_GP20 PF06810.6 KEY65271.1 - 0.0044 16.4 4.7 0.0044 16.4 3.3 11.1 3 2 9 12 12 12 3 Phage minor structural protein GP20 DivIC PF04977.10 KEY65271.1 - 0.0061 16.0 0.6 0.0061 16.0 0.4 13.3 9 4 3 13 13 13 2 Septum formation initiator Reo_sigmaC PF04582.7 KEY65271.1 - 0.01 15.0 52.8 0.057 12.5 4.9 6.9 3 2 4 8 8 8 0 Reovirus sigma C capsid protein ADH_zinc_N PF00107.21 KEY65271.1 - 0.068 12.7 0.1 0.16 11.5 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox PF00070.22 KEY65271.1 - 0.29 11.5 5.3 0.16 12.3 0.1 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase CENP-F_leu_zip PF10473.4 KEY65271.1 - 3.1 7.6 164.6 0.021 14.6 14.0 8.8 4 2 5 9 9 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2296 PF10058.4 KEY65272.1 - 1.5e-17 63.0 0.1 2.7e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) ALS2CR8 PF15299.1 KEY65272.1 - 0.017 14.6 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Cytadhesin_P30 PF07271.6 KEY65272.1 - 0.41 9.8 12.7 0.84 8.8 8.8 1.4 1 0 0 1 1 1 0 Cytadhesin P30/P32 zf-RanBP PF00641.13 KEY65272.1 - 0.47 9.5 2.2 0.97 8.5 0.1 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Pkinase PF00069.20 KEY65273.1 - 7.9e-41 139.9 0.2 1.2e-24 86.8 0.1 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEY65273.1 - 1.6e-14 53.6 0.1 5.5e-10 38.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Mating_C PF12737.2 KEY65273.1 - 0.037 12.9 0.1 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Med3 PF11593.3 KEY65274.1 - 0.066 12.4 3.0 0.073 12.2 2.1 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Med26 PF08711.6 KEY65275.1 - 2.7e-12 45.9 0.0 4.8e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Brr6_like_C_C PF10104.4 KEY65276.1 - 2.9e-29 101.3 1.8 3.9e-29 100.8 1.2 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Fungal_trans PF04082.13 KEY65277.1 - 3.1e-26 91.8 3.7 6e-26 90.8 0.7 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY65277.1 - 1.2e-07 31.4 12.1 2.2e-07 30.6 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.12 KEY65277.1 - 0.57 8.9 3.2 0.43 9.3 1.0 1.6 2 0 0 2 2 2 0 Clusterin zf-C2H2 PF00096.21 KEY65278.1 - 0.058 13.7 1.1 0.058 13.7 0.7 3.7 3 1 1 4 4 4 0 Zinc finger, C2H2 type Fzo_mitofusin PF04799.8 KEY65278.1 - 9.1 5.6 9.5 17 4.7 6.6 1.4 1 0 0 1 1 1 0 fzo-like conserved region Aa_trans PF01490.13 KEY65279.1 - 7.1e-45 153.2 32.9 9.3e-45 152.8 22.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF427 PF04248.7 KEY65280.1 - 2.5e-29 100.8 0.4 3.1e-29 100.4 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) bZIP_2 PF07716.10 KEY65281.1 - 9.4e-07 28.5 18.5 1.6e-06 27.8 12.8 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KEY65281.1 - 0.0094 15.8 15.6 0.017 15.0 10.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 KEY65281.1 - 0.02 15.1 11.3 0.038 14.2 7.8 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor APG6 PF04111.7 KEY65281.1 - 4 6.4 6.7 5.9 5.8 4.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Swi3 PF07962.7 KEY65282.1 - 1.6e-28 98.1 0.1 2.4e-28 97.5 0.1 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Cwf_Cwc_15 PF04889.7 KEY65282.1 - 0.059 13.0 3.9 4.3 6.9 0.8 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NADH-u_ox-rdase PF10785.4 KEY65283.1 - 2.8e-33 113.9 0.2 4.5e-33 113.3 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 KEY65283.1 - 9.7e-32 108.5 0.0 1.6e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Response_reg PF00072.19 KEY65284.1 - 6e-20 71.3 0.1 1.6e-19 69.9 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 KEY65284.1 - 7.4e-16 57.8 0.0 1.5e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KEY65284.1 - 2.4e-09 37.0 0.1 6.2e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 KEY65284.1 - 0.00033 20.3 0.0 0.00086 18.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CorA PF01544.13 KEY65285.1 - 1.4e-07 30.8 3.8 3.5e-07 29.5 2.6 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4079 PF13301.1 KEY65285.1 - 0.026 14.5 3.3 0.026 14.5 0.4 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF4079) DNA_repr_REX1B PF14966.1 KEY65285.1 - 0.049 14.0 0.3 0.21 12.0 0.0 2.0 2 1 1 3 3 3 0 DNA repair REX1-B DUF869 PF05911.6 KEY65285.1 - 0.053 11.7 0.3 0.07 11.3 0.2 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) SieB PF14163.1 KEY65285.1 - 0.1 12.1 0.8 0.24 10.9 0.3 1.7 2 0 0 2 2 2 0 Superinfection exclusion protein B Ribonuc_L-PSP PF01042.16 KEY65286.1 - 1.7e-29 102.0 0.0 2.2e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Hydrophobin_2 PF06766.6 KEY65287.1 - 1.8e-24 85.2 8.6 2.3e-24 84.8 6.0 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Xan_ur_permease PF00860.15 KEY65289.1 - 5.7e-25 87.6 29.5 3e-23 81.9 18.1 2.8 2 1 0 2 2 2 1 Permease family Sulfate_transp PF00916.15 KEY65289.1 - 3.3e-06 26.3 6.3 0.00018 20.6 2.5 2.7 1 1 1 2 2 2 2 Sulfate transporter family DUF3328 PF11807.3 KEY65290.1 - 4.5e-45 153.9 0.0 5.7e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) 2OG-FeII_Oxy PF03171.15 KEY65291.1 - 0.00037 20.7 0.0 0.00069 19.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KEY65291.1 - 0.0011 19.4 0.0 0.0032 17.9 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal Kelch_6 PF13964.1 KEY65293.1 - 3e-08 33.4 7.3 0.0072 16.4 0.0 5.5 5 1 1 6 6 6 2 Kelch motif Kelch_5 PF13854.1 KEY65293.1 - 7.3e-08 32.2 0.2 7.3e-08 32.2 0.1 5.0 6 0 0 6 6 6 1 Kelch motif Kelch_3 PF13415.1 KEY65293.1 - 1.3e-07 31.5 10.8 0.0036 17.4 0.0 5.6 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_4 PF13418.1 KEY65293.1 - 2e-06 27.4 20.1 0.0013 18.4 0.4 6.0 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.20 KEY65293.1 - 0.00046 19.6 4.3 0.74 9.4 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Adeno_E3_CR2 PF02439.10 KEY65293.1 - 0.081 12.4 0.6 0.14 11.6 0.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2273 PF10031.4 KEY65293.1 - 2.7 7.6 7.1 6.7 6.4 4.9 1.6 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) FMN_dh PF01070.13 KEY65294.1 - 3.7e-80 269.4 0.0 1.8e-47 161.9 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.20 KEY65294.1 - 0.042 12.7 0.0 0.078 11.8 0.0 1.4 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 KEY65294.1 - 0.089 11.8 0.1 7.2 5.6 0.0 2.3 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 KEY65294.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase ADH_zinc_N_2 PF13602.1 KEY65295.1 - 9.8e-15 55.5 0.0 2.5e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY65295.1 - 7.4e-07 28.9 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY65295.1 - 4.5e-05 23.0 0.1 8e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KEY65295.1 - 8.7e-05 22.6 0.2 0.00013 22.0 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEY65295.1 - 0.0093 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KEY65295.1 - 0.08 11.8 0.0 0.23 10.3 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain Peptidase_M49 PF03571.10 KEY65295.1 - 0.16 10.0 0.0 0.23 9.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M49 TPR_12 PF13424.1 KEY65296.1 - 3.8e-30 103.6 4.6 1.3e-11 44.2 0.0 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 KEY65296.1 - 6.7e-29 98.9 2.5 1.5e-09 37.4 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.9 KEY65296.1 - 3.7e-05 23.7 0.3 0.19 12.2 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 KEY65296.1 - 0.00034 20.6 0.2 0.16 12.0 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEY65296.1 - 0.00095 18.7 0.5 10 6.2 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEY65296.1 - 0.0042 17.1 0.0 6.5 7.2 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEY65296.1 - 0.1 12.2 0.0 0.98 9.1 0.0 2.4 1 1 0 2 2 2 0 TPR repeat Acyl-CoA_dh_M PF02770.14 KEY65298.1 - 1.3e-07 30.9 0.0 2.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HMG-CoA_red PF00368.13 KEY65298.1 - 0.086 11.4 0.1 0.37 9.4 0.1 1.9 2 0 0 2 2 2 0 Hydroxymethylglutaryl-coenzyme A reductase FtsJ PF01728.14 KEY65299.1 - 1.1e-16 61.3 0.0 1.8e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase EcKinase PF02958.15 KEY65300.1 - 7.8e-19 67.9 0.0 1.7e-18 66.8 0.0 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 KEY65300.1 - 1.1e-10 41.7 0.1 1.1e-10 41.7 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEY65300.1 - 0.075 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase F-box PF00646.28 KEY65301.1 - 8.3e-08 31.6 0.4 2.1e-07 30.4 0.3 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KEY65301.1 - 0.0017 18.0 0.2 0.004 16.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KEY65301.1 - 0.016 14.9 0.8 0.016 14.9 0.6 2.3 2 1 0 2 2 2 0 F-box-like domain Thymidylat_synt PF00303.14 KEY65302.1 - 1.1e-116 388.5 0.0 1.3e-116 388.3 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase UPF0113 PF03657.8 KEY65303.1 - 5.5e-07 29.3 0.0 1.3e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0113) Nol1_Nop2_Fmu_2 PF13636.1 KEY65303.1 - 0.00051 20.0 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 pre-rRNA processing and ribosome biogenesis PUA PF01472.15 KEY65303.1 - 0.0024 17.5 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 PUA domain Ctr PF04145.10 KEY65304.1 - 1.6e-43 148.1 1.4 2e-43 147.8 1.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family MAPEG PF01124.13 KEY65304.1 - 0.039 13.5 1.4 1 8.9 0.0 2.2 2 0 0 2 2 2 0 MAPEG family DUF4131 PF13567.1 KEY65304.1 - 0.56 9.5 3.2 19 4.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Pkinase PF00069.20 KEY65305.1 - 8.7e-34 116.8 0.0 1.2e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY65305.1 - 5.7e-20 71.4 0.0 8.4e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KEY65305.1 - 0.0056 15.7 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KEY65305.1 - 0.022 14.0 0.1 0.038 13.3 0.1 1.2 1 0 0 1 1 1 0 RIO1 family PD40 PF07676.7 KEY65305.1 - 0.062 12.9 0.0 7.5 6.3 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Kinase-like PF14531.1 KEY65305.1 - 0.13 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like AA_permease_2 PF13520.1 KEY65306.1 - 8.3e-61 205.8 38.8 9.8e-61 205.5 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEY65306.1 - 4.9e-26 91.1 37.6 1e-24 86.7 26.1 2.2 1 1 0 1 1 1 1 Amino acid permease SNF PF00209.13 KEY65307.1 - 6e-95 318.6 39.8 1.8e-59 201.6 12.2 2.6 3 0 0 3 3 3 2 Sodium:neurotransmitter symporter family SMP_2 PF10144.4 KEY65308.1 - 0.19 10.7 2.1 2.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial virulence factor haemolysin Glyco_hydro_47 PF01532.15 KEY65311.1 - 3.3e-168 560.0 0.1 3.9e-168 559.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 KEY65311.1 - 0.031 12.5 0.1 5.8 5.0 0.0 2.4 2 1 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) Alpha-amylase PF00128.19 KEY65312.1 - 1.4e-62 211.9 0.2 9e-62 209.2 0.1 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KEY65312.1 - 0.0015 18.5 0.1 0.0034 17.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Glyco_hydro_70 PF02324.11 KEY65312.1 - 0.0036 15.1 0.2 0.11 10.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 70 Aminotran_5 PF00266.14 KEY65312.1 - 0.19 10.4 0.1 0.33 9.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Barttin PF15462.1 KEY65313.1 - 0.15 11.7 0.0 0.42 10.2 0.0 1.7 1 1 1 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) CopD PF05425.8 KEY65314.1 - 0.023 14.8 0.6 0.35 11.1 0.3 2.4 2 0 0 2 2 2 0 Copper resistance protein D p450 PF00067.17 KEY65315.1 - 3.6e-48 164.2 0.0 4.6e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 N2227 PF07942.7 KEY65316.1 - 1.3e-61 207.9 0.0 2.1e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 N2227-like protein Transferase PF02458.10 KEY65316.1 - 5.8e-05 21.7 0.1 0.00044 18.8 0.0 2.3 2 1 0 2 2 2 1 Transferase family Methyltransf_12 PF08242.7 KEY65316.1 - 0.003 17.9 0.0 0.015 15.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY65316.1 - 0.004 16.8 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Sugar_tr PF00083.19 KEY65317.1 - 2e-112 376.0 26.8 2.2e-112 375.9 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY65317.1 - 1.9e-26 92.6 54.9 4e-25 88.2 15.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_9 PF13371.1 KEY65317.1 - 0.00073 19.3 0.3 0.0016 18.2 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat MFS_1 PF07690.11 KEY65319.1 - 6.5e-22 77.7 44.5 7.8e-22 77.4 28.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KEY65319.1 - 0.016 14.9 1.2 0.053 13.3 0.8 2.0 1 0 0 1 1 1 0 MFS_1 like family MFS_1 PF07690.11 KEY65320.1 - 5.7e-26 91.0 51.5 4.2e-17 61.8 9.1 3.6 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY65320.1 - 3e-11 42.5 13.0 4.4e-10 38.7 1.8 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KEY65320.1 - 0.011 14.1 25.7 0.0065 14.9 2.2 2.5 2 1 0 2 2 2 0 MFS/sugar transport protein Aconitase PF00330.15 KEY65320.1 - 0.16 10.3 0.1 0.23 9.8 0.1 1.1 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) DUF4293 PF14126.1 KEY65320.1 - 0.85 9.5 5.7 0.56 10.1 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF983 PF06170.7 KEY65320.1 - 1.2 9.2 5.3 1.3 9.1 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF983) zf-MYND PF01753.13 KEY65321.1 - 2.1 8.2 8.3 5.4 6.9 5.7 1.7 1 0 0 1 1 1 0 MYND finger Glyco_hydro_61 PF03443.9 KEY65322.1 - 2.3e-20 73.3 0.0 3.3e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 F-box-like PF12937.2 KEY65324.1 - 0.00072 19.2 0.0 0.017 14.8 0.0 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KEY65324.1 - 0.019 14.5 0.0 0.27 10.9 0.0 2.5 2 0 0 2 2 2 0 F-box domain DUF4158 PF13700.1 KEY65325.1 - 0.046 13.1 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) GMC_oxred_N PF00732.14 KEY65326.1 - 2.5e-37 128.6 0.1 5.6e-20 71.6 0.0 2.3 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY65326.1 - 2.7e-28 99.0 0.0 4.3e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase p450 PF00067.17 KEY65327.1 - 3.9e-54 183.9 0.0 5.2e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 KEY65328.1 - 0.01 15.7 9.3 0.011 15.6 5.5 1.7 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 KEY65329.1 - 2.9e-10 39.8 0.1 1.5e-09 37.5 0.0 2.1 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY65329.1 - 1.4e-08 34.3 0.1 2.2e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ketoacyl-synt PF00109.21 KEY65330.1 - 2.6e-71 240.0 0.9 4.9e-71 239.1 0.6 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEY65330.1 - 3.7e-38 131.6 0.4 1.6e-35 123.0 0.1 2.4 2 0 0 2 2 2 2 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KEY65330.1 - 1.4e-31 108.7 0.0 3.2e-31 107.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KEY65330.1 - 1.2e-26 93.1 0.0 2e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 KEY65330.1 - 1.3e-14 54.4 0.0 3.3e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KEY65330.1 - 2.4e-14 53.3 0.5 5.8e-14 52.1 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 KEY65330.1 - 1.8e-10 40.7 0.0 5.3e-09 35.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY65330.1 - 2e-10 40.4 0.0 4.8e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY65330.1 - 1.5e-06 28.6 0.0 5.5e-06 26.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 KEY65330.1 - 8.7e-06 25.3 0.0 2.3e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 KEY65330.1 - 1e-05 26.0 0.0 3.7e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KEY65330.1 - 7.1e-05 21.9 0.4 0.00024 20.2 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 KEY65330.1 - 0.00021 20.4 0.0 0.00046 19.3 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 KEY65330.1 - 0.00079 18.5 0.1 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.6 KEY65330.1 - 0.0038 16.6 0.0 0.0098 15.3 0.0 1.6 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.4 KEY65330.1 - 0.024 14.1 0.0 0.051 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase DXP_reductoisom PF02670.11 KEY65330.1 - 0.035 14.6 0.0 0.15 12.5 0.0 2.1 2 0 0 2 2 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Polysacc_synt_2 PF02719.10 KEY65330.1 - 0.091 11.6 0.0 0.32 9.8 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NmrA PF05368.8 KEY65330.1 - 0.16 11.1 0.0 0.33 10.1 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family AMP-binding PF00501.23 KEY65331.1 - 6.8e-79 265.1 0.0 1.1e-78 264.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KEY65331.1 - 1.1e-77 260.9 0.0 5.3e-77 258.7 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEY65331.1 - 1.4e-53 182.3 0.1 2.7e-53 181.3 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KEY65331.1 - 1.3e-48 165.0 0.5 3.4e-46 157.1 0.0 3.8 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 KEY65331.1 - 4.7e-42 143.7 0.0 1.9e-38 132.0 0.0 3.5 2 0 0 2 2 2 2 short chain dehydrogenase Condensation PF00668.15 KEY65331.1 - 4.5e-41 140.6 0.2 7.4e-41 139.9 0.1 1.3 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.1 KEY65331.1 - 4.8e-40 137.5 0.0 8.8e-40 136.6 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.7 KEY65331.1 - 3.6e-37 127.6 0.0 7.7e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 KEY65331.1 - 1.4e-28 99.1 0.0 3.7e-28 97.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KEY65331.1 - 3.3e-19 68.9 0.4 3.4e-09 36.8 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 KEY65331.1 - 6.9e-19 68.1 0.0 3.1e-18 66.0 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Epimerase PF01370.16 KEY65331.1 - 3.1e-16 59.5 0.0 3.9e-14 52.6 0.0 3.1 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.7 KEY65331.1 - 3.5e-11 43.4 0.0 2.6e-10 40.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY65331.1 - 1.2e-10 41.2 0.0 4.8e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY65331.1 - 3.7e-10 39.5 0.0 1.6e-09 37.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY65331.1 - 5.6e-09 36.5 0.0 4.2e-07 30.5 0.0 3.3 3 0 0 3 3 2 1 Methyltransferase domain HxxPF_rpt PF13745.1 KEY65331.1 - 9e-09 35.5 0.0 5.2e-08 33.0 0.0 2.4 2 0 0 2 2 1 1 HxxPF-repeated domain 3Beta_HSD PF01073.14 KEY65331.1 - 3e-08 32.7 0.0 9.4e-08 31.0 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.13 KEY65331.1 - 0.0019 17.3 0.0 0.0048 16.0 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 KEY65331.1 - 0.0021 17.1 0.0 0.0054 15.7 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 KEY65331.1 - 0.0028 17.1 0.0 0.0074 15.7 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 KEY65331.1 - 0.17 11.3 0.0 0.61 9.5 0.0 1.9 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) JCAD PF15351.1 KEY65331.1 - 1.4 6.4 0.1 2.1 5.8 0.1 1.1 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease EthD PF07110.6 KEY65332.1 - 1.3e-14 54.8 0.2 1.7e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 EthD domain MFS_1 PF07690.11 KEY65333.1 - 1.5e-39 135.7 55.6 2.4e-39 135.0 36.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KEY65333.1 - 3.1e-18 65.3 20.4 3.8e-18 65.0 14.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KEY65333.1 - 4.7e-10 38.6 15.0 4.7e-10 38.6 10.4 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter ABM PF03992.11 KEY65335.1 - 0.045 13.7 0.0 0.17 11.9 0.0 2.0 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Glyco_hydro_16 PF00722.16 KEY65336.1 - 3e-24 85.3 0.0 5e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 KEY65336.1 - 1.2e-08 33.5 1.2 0.0018 16.5 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_61 PF03443.9 KEY65337.1 - 4.5e-73 245.6 0.2 6.6e-73 245.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF2052 PF09747.4 KEY65337.1 - 1.9e-20 73.5 8.6 3.6e-19 69.4 6.0 2.0 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) NPCBM_assoc PF10633.4 KEY65337.1 - 0.016 15.2 0.1 8.6 6.4 0.0 3.2 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Glyco_hydro_43 PF04616.9 KEY65339.1 - 4.6e-30 104.6 0.4 1.5e-28 99.7 0.3 2.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_68 PF02435.11 KEY65339.1 - 0.18 10.4 2.3 11 4.6 0.1 3.2 3 1 1 4 4 4 0 Levansucrase/Invertase DUF3486 PF11985.3 KEY65341.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) Yae1_N PF09811.4 KEY65341.1 - 0.14 11.7 0.4 0.28 10.7 0.3 1.6 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Response_reg PF00072.19 KEY65342.1 - 1.9e-23 82.6 0.0 3.5e-16 59.1 0.0 2.4 1 1 1 2 2 2 2 Response regulator receiver domain DUF2000 PF09391.5 KEY65342.1 - 0.16 11.6 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) Bot1p PF12298.3 KEY65343.1 - 2.1e-49 167.8 1.8 3.3e-49 167.1 1.2 1.4 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Y_phosphatase3 PF13350.1 KEY65344.1 - 1.4e-39 136.0 0.0 1.9e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KEY65344.1 - 3.5e-17 62.2 0.1 9.1e-17 60.9 0.1 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 KEY65344.1 - 0.0029 16.9 0.0 0.0041 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase GLTT PF01744.15 KEY65344.1 - 8.7 5.8 7.3 36 3.8 0.0 3.3 3 0 0 3 3 3 0 GLTT repeat (6 copies) MARVEL PF01284.18 KEY65345.1 - 0.005 16.6 5.9 0.12 12.1 2.2 2.1 2 0 0 2 2 2 2 Membrane-associating domain DUF2516 PF10724.4 KEY65345.1 - 0.24 11.3 2.9 9.3 6.3 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2516) EI24 PF07264.6 KEY65345.1 - 1 8.7 6.1 1.7 7.9 4.3 1.4 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF4131 PF13567.1 KEY65345.1 - 8.1 5.8 6.9 1.2e+02 1.9 4.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2439 PF10382.4 KEY65347.1 - 7.7e-24 83.7 0.0 1.6e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Zn_clus PF00172.13 KEY65348.1 - 0.24 11.3 7.8 0.42 10.5 5.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain dCMP_cyt_deam_1 PF00383.17 KEY65350.1 - 6.2e-20 70.7 0.0 2.9e-19 68.6 0.0 2.0 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KEY65350.1 - 0.0028 17.5 3.2 0.19 11.5 2.2 3.0 1 1 0 1 1 1 1 Bd3614-like deaminase Lipase_3 PF01764.20 KEY65351.1 - 2.3e-17 62.9 0.0 4.4e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) TauD PF02668.11 KEY65352.1 - 8.4e-27 94.4 0.1 1e-26 94.1 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family tRNA-synt_1c PF00749.16 KEY65353.1 - 1.1e-94 316.6 0.0 1.7e-94 315.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KEY65353.1 - 2.5e-28 98.8 0.0 5.8e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Abhydrolase_6 PF12697.2 KEY65354.1 - 5.8e-15 55.7 0.0 7.6e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY65354.1 - 3.8e-06 26.7 0.0 5.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Aldo_ket_red PF00248.16 KEY65355.1 - 2e-41 141.6 0.0 2.4e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Citrate_synt PF00285.16 KEY65356.1 - 1.1e-114 382.9 0.0 1.4e-114 382.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase NmrA PF05368.8 KEY65357.1 - 0.0054 16.0 0.0 0.0089 15.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family p450 PF00067.17 KEY65358.1 - 2.8e-44 151.4 0.1 2.1e-29 102.3 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 GST_N_3 PF13417.1 KEY65359.1 - 1.7e-11 44.1 0.0 3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEY65359.1 - 3.9e-11 42.7 0.0 6.5e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEY65359.1 - 2e-06 27.5 2.7 5.4e-06 26.2 1.6 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KEY65359.1 - 0.00022 21.3 0.0 0.00069 19.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KEY65359.1 - 0.00055 19.8 0.0 0.00096 19.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Acyl-CoA_dh_1 PF00441.19 KEY65361.1 - 8.2e-41 139.5 0.5 1.2e-40 139.0 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KEY65361.1 - 6.2e-21 73.6 0.2 1.1e-20 72.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KEY65361.1 - 1.1e-20 74.2 0.0 2.6e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.23 KEY65361.1 - 5e-19 67.8 0.3 9.2e-19 67.0 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.6 KEY65361.1 - 1.3e-06 28.7 0.0 2.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain XPG_N PF00752.12 KEY65362.1 - 2.4e-31 107.9 1.6 2.5e-31 107.9 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 KEY65362.1 - 2.8e-30 104.2 0.0 6.3e-30 103.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 KEY65362.1 - 8.2e-06 25.9 0.1 4.6e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold WSC PF01822.14 KEY65364.1 - 5.2e-10 39.1 6.8 5.2e-10 39.1 4.7 1.7 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.5 KEY65364.1 - 0.00038 19.6 0.1 0.00085 18.5 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4366 PF14283.1 KEY65364.1 - 0.017 14.5 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Med3 PF11593.3 KEY65364.1 - 0.26 10.4 3.3 0.36 10.0 2.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Asp PF00026.18 KEY65365.1 - 1.2e-109 366.4 0.0 1.4e-109 366.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEY65365.1 - 2.8e-12 46.8 0.8 8.4e-12 45.3 0.0 2.3 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KEY65365.1 - 1.5e-06 28.6 0.1 0.017 15.5 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KEY65365.1 - 2.2e-06 27.3 0.0 4.2e-05 23.1 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 KEY65365.1 - 0.0019 17.9 0.1 3.6 7.4 0.0 3.0 2 1 1 3 3 3 2 gag-polyprotein putative aspartyl protease Alpha-amylase_C PF02806.13 KEY65365.1 - 0.04 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain DUF155 PF02582.9 KEY65367.1 - 8.7e-41 139.7 0.0 1.2e-40 139.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 CRAL_TRIO PF00650.15 KEY65368.1 - 1.2e-34 119.1 0.0 1.7e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KEY65368.1 - 3.6e-10 39.8 0.3 1.2e-09 38.1 0.2 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KEY65368.1 - 0.00087 19.2 0.0 0.0075 16.1 0.0 2.1 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Mis14 PF08641.7 KEY65369.1 - 5.4e-08 32.9 1.6 5.4e-08 32.9 1.1 2.5 2 1 1 3 3 3 1 Kinetochore protein Mis14 like LON PF02190.11 KEY65369.1 - 0.0057 16.3 0.3 0.011 15.3 0.2 1.5 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain DUF1515 PF07439.6 KEY65369.1 - 0.22 11.3 1.7 0.29 10.9 0.4 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) IGF2_C PF08365.6 KEY65369.1 - 0.5 10.1 3.2 19 5.0 0.0 2.7 2 0 0 2 2 2 0 Insulin-like growth factor II E-peptide bZIP_2 PF07716.10 KEY65369.1 - 1.6 8.6 5.1 20 5.0 0.8 3.2 3 0 0 3 3 3 0 Basic region leucine zipper AAA PF00004.24 KEY65371.1 - 2.4e-45 153.9 0.5 6.6e-45 152.5 0.0 2.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEY65371.1 - 3.1e-09 36.6 0.1 1.2e-08 34.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KEY65371.1 - 4.4e-08 33.2 0.0 9.1e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KEY65371.1 - 5.5e-07 29.7 0.0 1.7e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEY65371.1 - 9.3e-07 29.0 0.6 0.001 19.1 0.0 2.7 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 KEY65371.1 - 3e-06 26.3 0.0 5.6e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 KEY65371.1 - 0.00021 21.1 0.0 0.00059 19.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KEY65371.1 - 0.00036 19.6 0.0 0.00081 18.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 KEY65371.1 - 0.00045 19.9 0.2 0.056 13.0 0.0 3.1 4 0 0 4 4 3 1 NACHT domain AAA_17 PF13207.1 KEY65371.1 - 0.00045 21.0 0.0 0.0019 18.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.1 KEY65371.1 - 0.00046 20.1 0.0 0.00088 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KEY65371.1 - 0.0012 17.6 0.0 0.0021 16.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 KEY65371.1 - 0.0013 18.4 0.2 0.0035 17.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 KEY65371.1 - 0.0013 17.8 0.1 0.0037 16.3 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 KEY65371.1 - 0.0016 18.6 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 KEY65371.1 - 0.0029 17.3 0.0 0.0092 15.6 0.0 1.9 2 0 0 2 2 1 1 NTPase AAA_3 PF07726.6 KEY65371.1 - 0.0038 16.8 0.0 0.011 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KEY65371.1 - 0.0046 16.5 0.0 0.039 13.5 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 KEY65371.1 - 0.0053 16.3 0.1 0.018 14.6 0.0 1.9 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 KEY65371.1 - 0.0058 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEY65371.1 - 0.0062 15.9 0.8 0.075 12.4 0.1 2.4 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KEY65371.1 - 0.0066 15.6 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KEY65371.1 - 0.0098 15.4 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KEY65371.1 - 0.0099 15.3 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Arch_ATPase PF01637.13 KEY65371.1 - 0.011 15.4 0.9 0.06 13.0 0.0 2.4 2 1 1 3 3 3 0 Archaeal ATPase AAA_24 PF13479.1 KEY65371.1 - 0.012 15.2 0.1 0.03 13.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 KEY65371.1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_23 PF13476.1 KEY65371.1 - 0.02 15.1 0.4 0.81 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Viral_Hsp90 PF03225.9 KEY65371.1 - 0.024 12.9 0.0 0.039 12.2 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue KaiC PF06745.8 KEY65371.1 - 0.03 13.4 0.7 0.45 9.5 0.0 2.4 3 0 0 3 3 3 0 KaiC AAA_18 PF13238.1 KEY65371.1 - 0.03 14.6 0.0 0.1 12.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KEY65371.1 - 0.042 13.8 0.0 0.31 11.0 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.11 KEY65371.1 - 0.043 12.6 0.0 0.13 11.0 0.0 1.7 2 0 0 2 2 2 0 AFG1-like ATPase Sigma54_activat PF00158.21 KEY65371.1 - 0.047 13.1 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 KEY65371.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 KEY65371.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_10 PF12846.2 KEY65371.1 - 0.26 10.7 1.9 1.4 8.2 0.3 2.9 3 1 0 3 3 2 0 AAA-like domain Folliculin PF11704.3 KEY65372.1 - 1.4e-28 99.5 0.0 1.3e-27 96.4 0.0 2.1 2 0 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport AAA PF00004.24 KEY65374.1 - 1.9e-28 99.3 0.0 5.3e-14 52.5 0.0 3.6 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEY65374.1 - 3.4e-13 49.8 6.4 0.02 15.0 0.0 6.4 3 3 1 4 4 4 3 AAA domain AAA_5 PF07728.9 KEY65374.1 - 9.1e-11 41.6 0.1 0.023 14.4 0.0 4.1 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KEY65374.1 - 2.1e-10 41.4 6.8 0.028 15.2 0.7 4.3 4 1 0 4 4 3 3 AAA domain AAA_19 PF13245.1 KEY65374.1 - 2.7e-08 33.4 2.3 0.013 15.1 0.0 3.9 3 0 0 3 3 3 2 Part of AAA domain AAA_18 PF13238.1 KEY65374.1 - 5.4e-07 29.9 1.6 0.48 10.7 0.0 3.9 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 KEY65374.1 - 7.6e-07 29.0 0.1 0.25 11.2 0.0 3.7 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 KEY65374.1 - 1.1e-06 28.7 0.0 1.5 8.9 0.0 3.7 3 0 0 3 3 3 2 RNA helicase Mg_chelatase PF01078.16 KEY65374.1 - 1.5e-06 27.5 0.1 0.33 10.0 0.0 3.6 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 KEY65374.1 - 2e-06 27.9 6.1 0.34 10.8 0.0 5.0 4 2 2 6 6 5 2 AAA ATPase domain AAA_24 PF13479.1 KEY65374.1 - 4.1e-06 26.5 0.4 1.1 8.7 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 KEY65374.1 - 6.5e-06 26.1 2.0 1.1 9.2 0.0 3.7 3 0 0 3 3 3 2 AAA domain Sigma54_activ_2 PF14532.1 KEY65374.1 - 2e-05 24.6 0.0 0.77 9.8 0.0 3.9 3 2 0 3 3 3 1 Sigma-54 interaction domain AAA_30 PF13604.1 KEY65374.1 - 2e-05 24.2 0.7 0.77 9.3 0.1 4.4 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 KEY65374.1 - 3.6e-05 23.2 0.1 0.15 11.4 0.0 3.6 3 1 0 3 3 3 1 IstB-like ATP binding protein RuvB_N PF05496.7 KEY65374.1 - 3.9e-05 22.8 0.1 0.66 8.9 0.0 3.9 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 KEY65374.1 - 0.00025 20.5 1.0 0.35 10.3 0.0 4.1 4 1 0 4 4 4 1 Sigma-54 interaction domain AAA_11 PF13086.1 KEY65374.1 - 0.00081 19.0 0.0 1.3 8.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain VirE PF05272.6 KEY65374.1 - 0.00081 18.9 0.0 0.012 15.0 0.0 2.7 3 0 0 3 3 3 1 Virulence-associated protein E Torsin PF06309.6 KEY65374.1 - 0.00097 19.0 0.0 9.1 6.1 0.0 3.8 4 0 0 4 4 3 0 Torsin Viral_helicase1 PF01443.13 KEY65374.1 - 0.0011 18.5 0.1 6.1 6.2 0.0 3.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase MobB PF03205.9 KEY65374.1 - 0.0012 18.5 1.0 1.1 8.8 0.1 3.5 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KEY65374.1 - 0.0014 18.1 3.9 3.2 7.1 0.0 4.3 3 1 1 4 4 4 1 AAA-like domain ABC_tran PF00005.22 KEY65374.1 - 0.0017 18.6 0.6 2 8.6 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_29 PF13555.1 KEY65374.1 - 0.0066 15.9 0.2 1.7 8.2 0.0 3.4 4 0 0 4 4 4 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KEY65374.1 - 0.0084 15.5 0.3 4.9 6.5 0.0 3.7 3 0 0 3 3 3 0 AAA domain PRK PF00485.13 KEY65374.1 - 0.021 14.3 0.3 18 4.8 0.0 3.3 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family SKI PF01202.17 KEY65374.1 - 0.027 14.3 0.1 45 3.8 0.0 3.5 3 0 0 3 3 3 0 Shikimate kinase AAA_32 PF13654.1 KEY65374.1 - 0.045 12.4 0.1 0.24 10.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.17 KEY65374.1 - 0.047 13.1 0.2 1.9 7.9 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain KTI12 PF08433.5 KEY65374.1 - 0.066 12.4 0.0 9 5.4 0.0 2.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 KEY65374.1 - 0.072 12.1 0.1 6.6 5.7 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin ResIII PF04851.10 KEY65374.1 - 0.17 11.7 0.1 55 3.5 0.0 3.8 4 1 1 5 5 4 0 Type III restriction enzyme, res subunit PSP PF04046.11 KEY65374.1 - 1.4 8.3 4.1 0.97 8.8 0.7 2.1 2 0 0 2 2 2 0 PSP DNA_methylase PF00145.12 KEY65375.1 - 7.6e-29 100.8 0.0 1.4e-28 100.0 0.0 1.4 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 KEY65375.1 - 3.7e-05 23.4 0.0 0.0082 15.8 0.0 2.5 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.3 KEY65375.1 - 0.017 14.8 0.0 0.041 13.5 0.0 1.6 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain Drc1-Sld2 PF11719.3 KEY65376.1 - 4.2e-98 329.2 14.4 4.7e-98 329.0 10.0 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein FliT PF05400.8 KEY65376.1 - 0.027 14.8 0.4 0.058 13.8 0.3 1.6 1 0 0 1 1 1 0 Flagellar protein FliT vMSA PF00695.14 KEY65376.1 - 0.071 12.3 1.2 0.08 12.1 0.2 1.5 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus Drf_FH3 PF06367.11 KEY65376.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Diaphanous FH3 Domain zf-RING_2 PF13639.1 KEY65377.1 - 8.5e-06 25.5 10.8 8.5e-06 25.5 7.5 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KEY65377.1 - 1.5e-05 24.5 6.7 2.9e-05 23.6 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEY65377.1 - 2e-05 24.1 7.2 3.4e-05 23.4 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEY65377.1 - 2.4e-05 24.2 8.2 2.4e-05 24.2 5.7 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEY65377.1 - 0.00067 19.7 7.7 0.0019 18.2 5.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger DASH_Spc34 PF08657.5 KEY65378.1 - 4.1e-51 174.1 2.1 3.2e-50 171.1 1.5 1.9 1 1 0 1 1 1 1 DASH complex subunit Spc34 NOA36 PF06524.7 KEY65378.1 - 0.57 9.3 4.9 0.83 8.8 3.4 1.1 1 0 0 1 1 1 0 NOA36 protein Rpn3_C PF08375.6 KEY65380.1 - 2.8e-24 85.3 1.4 8e-24 83.8 1.0 1.9 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 KEY65380.1 - 4.8e-19 68.6 0.0 1.3e-18 67.1 0.0 1.8 1 0 0 1 1 1 1 PCI domain TFIID_20kDa PF03847.8 KEY65380.1 - 4.6e-17 62.0 0.0 9.7e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TPR_2 PF07719.12 KEY65380.1 - 0.015 15.1 0.8 0.055 13.3 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_6 PF13516.1 KEY65381.1 - 9.1e-16 56.1 0.1 0.043 13.8 0.0 7.5 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.2 KEY65381.1 - 0.0013 18.3 0.0 0.96 9.1 0.0 4.0 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEY65381.1 - 0.056 13.4 0.1 65 4.1 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 KEY65381.1 - 0.18 12.1 0.9 67 4.3 0.0 4.4 5 0 0 5 5 5 0 Leucine rich repeat MOZ_SAS PF01853.13 KEY65382.1 - 1.1e-50 171.4 0.0 2.1e-50 170.5 0.0 1.4 1 0 0 1 1 1 1 MOZ/SAS family DUF2098 PF09871.4 KEY65382.1 - 0.056 13.3 0.2 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) ATP-synt_C PF00137.16 KEY65383.1 - 3.1e-16 59.0 10.5 5.4e-16 58.2 7.3 1.4 1 0 0 1 1 1 1 ATP synthase subunit C DNA_pol_A_exo1 PF01612.15 KEY65384.1 - 3.2e-38 130.9 0.6 4.7e-38 130.4 0.1 1.5 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.7 KEY65384.1 - 3.3e-23 81.8 0.2 3.3e-23 81.8 0.1 2.1 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 KEY65384.1 - 1.4e-10 40.7 0.0 3.7e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Glyco_transf_20 PF00982.16 KEY65385.1 - 5.5e-196 651.6 0.0 6.6e-196 651.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 KEY65385.1 - 0.035 13.5 0.1 0.091 12.2 0.1 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain VID27 PF08553.5 KEY65386.1 - 0 1076.2 0.0 0 1075.9 0.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Prenylcys_lyase PF07156.9 KEY65387.1 - 1.2e-25 90.1 0.0 1.2e-15 57.3 0.0 2.2 2 0 0 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 KEY65387.1 - 1.1e-12 47.8 0.0 2.3e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KEY65387.1 - 9.8e-08 31.4 0.0 1.7e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 KEY65387.1 - 1.2e-06 27.6 0.1 1.1e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KEY65387.1 - 2.7e-05 23.9 0.0 6.6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KEY65387.1 - 0.00025 21.1 0.1 0.0026 17.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEY65387.1 - 0.00059 19.7 0.6 0.021 14.6 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEY65387.1 - 0.0074 15.1 0.3 0.011 14.5 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.15 KEY65387.1 - 0.018 15.1 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 KEY65387.1 - 0.026 13.6 0.0 0.057 12.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 KEY65387.1 - 0.079 12.3 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 KEY65387.1 - 0.083 11.7 0.3 0.12 11.2 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FRQ PF09421.5 KEY65388.1 - 0 1259.3 49.9 0 1258.8 34.6 1.1 1 0 0 1 1 1 1 Frequency clock protein MscS_porin PF12795.2 KEY65388.1 - 0.097 11.9 0.5 0.17 11.1 0.4 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Metalloenzyme PF01676.13 KEY65389.1 - 1.8e-70 237.2 0.0 2e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 KEY65389.1 - 5.1e-70 235.2 0.0 6.8e-70 234.8 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 KEY65389.1 - 1.7e-07 30.9 0.0 2.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KEY65389.1 - 6.3e-05 22.2 0.0 0.00013 21.2 0.0 1.6 1 1 0 1 1 1 1 Sulfatase AP_endonuc_2 PF01261.19 KEY65389.1 - 0.011 15.0 0.0 0.042 13.1 0.0 1.9 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Med9 PF07544.8 KEY65390.1 - 1.9e-20 72.3 0.6 7.5e-20 70.4 0.2 1.8 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.3 KEY65390.1 - 0.038 13.9 0.1 0.055 13.4 0.1 1.2 1 0 0 1 1 1 0 Subunit 21 of Mediator complex IATP PF04568.7 KEY65390.1 - 0.038 14.0 0.2 0.078 13.0 0.1 1.4 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Phage_GP20 PF06810.6 KEY65390.1 - 0.068 12.6 0.1 0.088 12.2 0.1 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 TBCC PF07986.7 KEY65391.1 - 2.6e-32 110.7 0.0 4.3e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C Gpi1 PF05024.10 KEY65393.1 - 7.8e-64 214.8 7.4 7.8e-64 214.8 5.1 2.1 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) UPF0203 PF05254.7 KEY65393.1 - 1.3e-25 89.0 2.0 2.3e-25 88.2 1.4 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Tom37_C PF11801.3 KEY65393.1 - 0.12 12.1 1.1 4.8 7.0 0.1 2.5 2 0 0 2 2 2 0 Tom37 C-terminal domain COX17 PF05051.8 KEY65393.1 - 0.69 9.9 2.6 0.77 9.8 0.4 2.1 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Aldose_epim PF01263.15 KEY65395.1 - 9.8e-61 205.4 0.1 1.2e-60 205.1 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DUF1509 PF07420.6 KEY65396.1 - 0.00012 21.4 7.4 0.00015 21.2 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1509) DUF3767 PF12597.3 KEY65397.1 - 5e-30 103.5 0.0 6.9e-30 103.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF1318 PF07027.7 KEY65397.1 - 0.096 12.9 1.1 0.16 12.2 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1318) DUF1744 PF08490.7 KEY65398.1 - 4.2e-150 499.7 0.0 5.8e-150 499.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 KEY65398.1 - 2.8e-64 217.0 0.5 2.8e-64 217.0 0.3 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 KEY65398.1 - 8e-23 80.9 0.2 3.4e-22 78.8 0.2 1.9 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 KEY65398.1 - 4.9e-10 39.2 0.1 1.2e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KEY65398.1 - 1.9e-06 27.8 0.0 1e-05 25.4 0.0 2.3 1 0 0 1 1 1 1 RNase_H superfamily HET PF06985.6 KEY65399.1 - 6.6e-26 91.1 0.1 1.5e-25 89.9 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Clathrin PF00637.15 KEY65401.1 - 3.8e-20 71.9 5.0 8.1e-20 70.8 0.4 2.8 2 1 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 KEY65401.1 - 3.3e-05 23.5 1.9 0.38 10.7 0.3 4.2 3 1 0 3 3 3 2 WD domain, G-beta repeat zf-RING_2 PF13639.1 KEY65401.1 - 4.9e-05 23.0 0.3 0.00011 21.9 0.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KEY65401.1 - 6.3e-05 22.6 0.4 0.00016 21.3 0.3 1.7 1 1 0 1 1 1 1 zinc-RING finger domain Vps39_1 PF10366.4 KEY65401.1 - 0.0066 16.4 0.3 0.029 14.3 0.1 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 zf-RING_UBOX PF13445.1 KEY65401.1 - 0.044 13.5 0.2 0.16 11.7 0.0 2.1 2 0 0 2 2 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 KEY65401.1 - 0.3 11.2 2.0 0.25 11.4 0.2 1.7 2 0 0 2 2 1 0 RING-H2 zinc finger DUF2457 PF10446.4 KEY65401.1 - 2 7.0 21.9 4.3 5.9 15.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.5 KEY65401.1 - 3.4 6.6 15.6 0.025 13.6 4.6 1.9 2 0 0 2 2 2 0 BUD22 PPP4R2 PF09184.6 KEY65401.1 - 3.7 7.0 24.0 8.2 5.8 16.6 1.5 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.8 KEY65401.1 - 3.8 7.3 19.7 9 6.0 13.6 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 KEY65401.1 - 5.4 4.7 22.6 10 3.8 15.7 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KEY65401.1 - 8.7 4.2 14.3 20 3.0 9.9 1.5 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 KEY65401.1 - 9.9 5.6 20.5 76 2.7 13.0 2.5 2 0 0 2 2 2 0 Nucleoplasmin Apc1 PF12859.2 KEY65402.1 - 7.1e-26 90.4 0.1 7.1e-26 90.4 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 KEY65402.1 - 3.7e-06 26.8 0.3 0.0071 16.5 0.0 4.2 4 0 0 4 4 4 2 Proteasome/cyclosome repeat eIF3_N PF09440.5 KEY65403.1 - 1.6e-43 148.0 0.7 3.4e-43 146.9 0.5 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 KEY65403.1 - 1.6e-13 50.8 0.0 4.1e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.1 KEY65403.1 - 0.027 15.0 0.4 19 6.2 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Img2 PF05046.9 KEY65404.1 - 1.4e-18 66.9 0.0 2.8e-18 65.9 0.1 1.5 2 0 0 2 2 2 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 KEY65404.1 - 0.052 13.3 2.2 0.26 11.1 1.5 2.0 1 1 0 1 1 1 0 Translation initiation factor SUI1 ARID PF01388.16 KEY65405.1 - 8.3e-20 70.4 1.6 1.3e-19 69.7 0.0 2.2 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain U3_assoc_6 PF08640.6 KEY65406.1 - 1.8e-24 85.2 0.3 9.7e-24 82.9 0.2 2.2 2 1 1 3 3 3 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 KEY65406.1 - 0.00077 18.4 3.8 0.0013 17.6 2.1 1.7 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_11 PF13414.1 KEY65406.1 - 0.096 12.3 0.2 0.56 9.8 0.0 2.3 2 0 0 2 2 2 0 TPR repeat Frag1 PF10277.4 KEY65407.1 - 3.4e-38 131.2 7.1 3.4e-38 131.2 4.9 2.7 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family p450 PF00067.17 KEY65408.1 - 8.2e-60 202.6 0.0 1.3e-59 202.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AurF PF11583.3 KEY65408.1 - 0.16 10.8 0.1 0.28 10.0 0.1 1.3 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF Ribosomal_S10 PF00338.17 KEY65409.1 - 1e-29 102.2 0.4 1.3e-29 101.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Fibrillarin_2 PF10113.4 KEY65409.1 - 0.012 13.9 0.0 0.013 13.8 0.0 1.1 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein DUF4469 PF14734.1 KEY65409.1 - 0.029 14.2 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold CUE PF02845.11 KEY65410.1 - 4.2e-10 38.9 0.1 8.5e-10 37.9 0.0 1.6 1 0 0 1 1 1 1 CUE domain zf-C2H2_4 PF13894.1 KEY65411.1 - 7.9e-05 22.7 5.7 0.49 10.8 0.1 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY65411.1 - 0.00012 22.2 3.3 2.1 8.8 0.1 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type GatB_N PF02934.10 KEY65412.1 - 1e-100 336.3 0.0 1.3e-100 335.9 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 KEY65412.1 - 7e-12 45.2 0.0 2.7e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 GatB domain LEA_4 PF02987.11 KEY65414.1 - 0.0031 17.3 4.1 0.0031 17.3 2.9 3.2 3 1 1 4 4 4 2 Late embryogenesis abundant protein DUF883 PF05957.8 KEY65414.1 - 0.037 14.4 8.2 0.033 14.5 3.4 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 KEY65414.1 - 0.047 13.2 2.8 0.074 12.5 2.0 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain CsbD PF05532.7 KEY65414.1 - 0.14 11.8 20.6 11 5.7 11.1 4.0 1 1 1 2 2 2 0 CsbD-like YtxH PF12732.2 KEY65414.1 - 2.3 8.6 11.5 1.8e+02 2.5 8.0 2.6 1 1 0 1 1 1 0 YtxH-like protein DivIVA PF05103.8 KEY65414.1 - 2.5 8.1 8.3 17 5.4 5.7 2.0 1 1 0 1 1 1 0 DivIVA protein Grp1_Fun34_YaaH PF01184.14 KEY65415.1 - 1.5e-55 187.7 12.7 2e-55 187.3 8.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DnaJ PF00226.26 KEY65416.1 - 2e-09 37.0 1.0 3.9e-09 36.1 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain Opi1 PF08618.5 KEY65416.1 - 0.39 9.5 4.6 0.54 9.1 3.2 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 ECH PF00378.15 KEY65417.1 - 1.3e-47 162.0 0.1 5.1e-45 153.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family UCH PF00443.24 KEY65418.1 - 4.4e-41 140.7 0.0 9.6e-41 139.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEY65418.1 - 2.4e-17 63.3 0.1 1e-09 38.2 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 KEY65418.1 - 9.3e-05 21.7 1.5 0.76 9.2 0.0 3.6 3 0 0 3 3 3 2 A repeated domain in UCH-protein Ank_2 PF12796.2 KEY65420.1 - 9.2e-17 61.1 0.2 9.7e-05 22.6 0.0 5.5 2 2 3 5 5 5 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEY65420.1 - 3.1e-12 45.6 6.9 0.00013 21.5 0.0 6.4 6 1 0 6 6 6 2 Ankyrin repeat Ank_3 PF13606.1 KEY65420.1 - 2.1e-11 42.8 0.4 0.003 17.6 0.0 6.0 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 KEY65420.1 - 6.5e-07 29.3 1.6 0.28 11.4 0.0 4.7 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEY65420.1 - 7.6e-07 29.4 0.2 4.2 8.0 0.0 5.4 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Adeno_E4 PF05385.6 KEY65420.1 - 0.097 12.6 0.2 2.5 8.1 0.0 3.1 4 0 0 4 4 4 0 Mastadenovirus early E4 13 kDa protein TFIIA PF03153.8 KEY65420.1 - 0.78 9.5 13.7 0.54 10.0 3.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF1524 PF07510.6 KEY65421.1 - 1.1e-14 54.4 0.0 1.5e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.1 KEY65421.1 - 0.15 11.7 0.0 10 5.8 0.0 2.3 2 0 0 2 2 2 0 HNH endonuclease Glyco_hydro_16 PF00722.16 KEY65423.1 - 1.3e-05 24.5 0.1 0.0046 16.2 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Sec7 PF01369.15 KEY65424.1 - 3e-43 147.6 0.0 5.7e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KEY65424.1 - 2.7e-21 75.9 0.0 9.3e-21 74.1 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain FMO-like PF00743.14 KEY65425.1 - 2.3e-32 111.9 0.0 2e-24 85.7 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KEY65425.1 - 1.5e-15 57.8 0.0 3.4e-15 56.6 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEY65425.1 - 2.7e-11 42.9 0.0 6.4e-10 38.4 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KEY65425.1 - 6e-07 29.3 0.1 9.9e-06 25.4 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KEY65425.1 - 4.1e-06 26.8 0.0 1.7e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY65425.1 - 4.3e-05 23.4 0.0 0.00032 20.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KEY65425.1 - 0.05 12.6 0.8 1.4 7.8 0.1 2.8 3 0 0 3 3 3 0 FAD binding domain DAO PF01266.19 KEY65425.1 - 0.085 11.7 0.0 7.3 5.3 0.0 3.1 4 0 0 4 4 4 0 FAD dependent oxidoreductase Amidohydro_2 PF04909.9 KEY65427.1 - 2.7e-14 53.3 0.0 1.3e-13 51.1 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KEY65427.1 - 0.0079 15.8 0.2 0.53 9.8 0.2 2.4 1 1 0 1 1 1 1 Amidohydrolase family Glycos_transf_N PF04413.11 KEY65427.1 - 0.043 12.9 0.1 0.77 8.9 0.0 2.2 2 0 0 2 2 2 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Amidohydro_4 PF13147.1 KEY65427.1 - 0.054 13.5 0.8 0.13 12.2 0.5 1.7 1 1 0 1 1 1 0 Amidohydrolase FTR_C PF02741.10 KEY65427.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 FTR, proximal lobe CoA_binding_2 PF13380.1 KEY65427.1 - 0.082 13.0 0.0 0.35 11.0 0.0 2.0 2 0 0 2 2 2 0 CoA binding domain DUF676 PF05057.9 KEY65428.1 - 7.9e-05 22.0 0.1 0.00018 20.8 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KEY65428.1 - 0.00018 21.4 1.5 0.00033 20.6 1.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY65428.1 - 0.0087 15.8 0.0 0.016 14.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family FHA PF00498.21 KEY65429.1 - 1.7e-14 53.6 0.0 2.8e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain Di19_C PF14571.1 KEY65430.1 - 0.068 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal HAD_2 PF13419.1 KEY65431.1 - 8.8e-25 87.9 0.0 1e-24 87.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEY65431.1 - 0.0071 16.7 0.0 0.015 15.6 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEY65431.1 - 0.0096 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HsbA PF12296.3 KEY65431.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Hydrophobic surface binding protein A HNH PF01844.18 KEY65432.1 - 0.00016 21.4 1.3 0.00032 20.4 0.9 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.1 KEY65432.1 - 0.085 12.6 0.6 0.19 11.5 0.4 1.6 1 0 0 1 1 1 0 HNH endonuclease FA_desaturase PF00487.19 KEY65435.1 - 6.5e-26 91.3 24.1 1e-25 90.6 16.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KEY65435.1 - 3.7e-05 23.7 0.0 6.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) OB_NTP_bind PF07717.11 KEY65436.1 - 2.6e-14 53.0 0.0 5.6e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KEY65436.1 - 6.9e-10 38.8 0.0 1.4e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) T2SE PF00437.15 KEY65436.1 - 5.9e-05 22.0 0.0 0.00016 20.7 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 KEY65436.1 - 0.0026 17.7 0.0 0.031 14.2 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain KaiC PF06745.8 KEY65436.1 - 0.015 14.4 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 KEY65436.1 - 0.017 15.2 0.0 0.038 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEY65436.1 - 0.027 13.9 0.0 0.096 12.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KEY65436.1 - 0.099 12.9 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DEAD PF00270.24 KEY65436.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase NACHT PF05729.7 KEY65436.1 - 0.15 11.6 0.2 1.3 8.6 0.2 2.2 1 1 0 1 1 1 0 NACHT domain Fungal_trans PF04082.13 KEY65437.1 - 4.4e-16 58.5 0.1 9e-16 57.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY65437.1 - 2e-06 27.5 11.7 2e-06 27.5 8.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LAMTOR PF15454.1 KEY65437.1 - 0.096 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator ADH_zinc_N PF00107.21 KEY65438.1 - 2.6e-09 36.7 0.1 5.6e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NmrA PF05368.8 KEY65438.1 - 0.011 14.9 0.5 0.016 14.4 0.4 1.2 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.1 KEY65438.1 - 0.022 14.7 0.2 0.039 13.9 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding ADH_N PF08240.7 KEY65438.1 - 0.023 14.4 0.0 0.1 12.3 0.0 2.2 2 1 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 KEY65441.1 - 2.2e-12 47.1 1.1 4.1e-12 46.3 0.8 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY65441.1 - 6.4e-06 25.9 2.6 6.5e-06 25.9 0.6 1.7 2 0 0 2 2 2 1 KR domain CorA PF01544.13 KEY65442.1 - 1.3e-08 34.2 4.2 1.9e-08 33.7 2.1 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Nop25 PF09805.4 KEY65442.1 - 5.1 7.1 10.1 0.97 9.4 3.4 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) SDF PF00375.13 KEY65443.1 - 8.8e-91 304.5 30.9 1.1e-90 304.2 21.4 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Nuc_deoxyrib_tr PF05014.10 KEY65444.1 - 0.031 14.1 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase p450 PF00067.17 KEY65445.1 - 1e-73 248.5 0.0 1.3e-73 248.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1206 PF06724.6 KEY65445.1 - 0.032 13.9 4.8 0.064 13.0 3.3 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) Acetyltransf_1 PF00583.19 KEY65446.1 - 7e-10 38.8 0.0 9.8e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEY65446.1 - 7.7e-09 35.5 0.1 1.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEY65446.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1100 PF06500.6 KEY65447.1 - 1.5e-14 53.4 0.0 1.9e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_5 PF12695.2 KEY65447.1 - 1.7e-10 40.8 0.0 3.4e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY65447.1 - 3.8e-10 40.0 2.4 1e-09 38.6 0.2 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEY65447.1 - 0.00055 19.2 0.0 0.001 18.3 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family TPR_12 PF13424.1 KEY65447.1 - 0.0019 18.0 0.1 0.0042 16.9 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEY65447.1 - 0.011 15.5 1.3 0.027 14.3 0.9 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 KEY65447.1 - 0.017 14.7 0.1 0.035 13.7 0.1 1.4 1 0 0 1 1 1 0 TPR repeat BAAT_C PF08840.6 KEY65447.1 - 0.02 14.6 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 KEY65447.1 - 0.022 14.3 0.0 1.8 8.1 0.0 2.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold TPR_16 PF13432.1 KEY65447.1 - 0.026 15.1 0.2 0.098 13.3 0.1 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat PA PF02225.17 KEY65447.1 - 0.039 13.6 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 PA domain TPR_1 PF00515.23 KEY65447.1 - 0.099 12.2 0.9 0.19 11.4 0.6 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat adh_short PF00106.20 KEY65448.1 - 5.5e-32 110.9 0.4 7.5e-32 110.5 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY65448.1 - 1.1e-21 77.7 0.0 1.4e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY65448.1 - 4.7e-14 52.4 0.7 1.1e-13 51.3 0.5 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY65448.1 - 4.2e-05 23.0 0.0 6.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KEY65448.1 - 0.00012 21.7 0.8 0.00025 20.7 0.5 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 KEY65448.1 - 0.0072 15.2 0.4 0.014 14.3 0.1 1.6 2 1 0 2 2 2 1 RmlD substrate binding domain 2-Hacid_dh_C PF02826.14 KEY65448.1 - 0.02 14.0 0.0 0.068 12.3 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KEY65448.1 - 0.02 14.8 1.7 0.067 13.1 0.6 2.3 1 1 1 2 2 2 0 NADH(P)-binding Toprim_3 PF13362.1 KEY65448.1 - 0.051 13.8 0.1 5.3 7.3 0.0 2.6 2 1 0 2 2 2 0 Toprim domain ADH_zinc_N PF00107.21 KEY65448.1 - 0.1 12.1 0.2 0.23 11.0 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Aldo_ket_red PF00248.16 KEY65449.1 - 8.2e-49 165.9 0.0 1e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SNARE PF05739.14 KEY65450.1 - 4e-18 64.8 0.7 4e-18 64.8 0.5 3.2 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 KEY65450.1 - 4.8e-16 58.7 0.8 4.8e-16 58.7 0.5 3.0 3 1 0 3 3 3 1 Syntaxin MCPsignal PF00015.16 KEY65450.1 - 0.00068 19.2 4.4 0.0019 17.7 0.4 2.4 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Sed5p PF11416.3 KEY65450.1 - 0.028 13.8 0.0 0.074 12.4 0.0 1.7 1 0 0 1 1 1 0 Integral membrane protein Sed5p zf-C4H2 PF10146.4 KEY65450.1 - 0.036 14.0 2.6 0.75 9.7 0.2 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein E2R135 PF11570.3 KEY65450.1 - 0.068 13.2 3.4 8.3 6.5 1.4 2.5 2 1 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 NPV_P10 PF05531.7 KEY65450.1 - 0.072 13.3 5.1 24 5.2 0.1 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.4 KEY65450.1 - 0.086 11.7 9.9 0.23 10.3 0.3 3.0 2 1 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 KEY65450.1 - 0.15 10.5 7.8 0.27 9.6 3.2 2.0 2 0 0 2 2 2 0 AAA domain KxDL PF10241.4 KEY65450.1 - 0.15 11.9 3.5 5.5 6.9 0.2 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein BLOC1_2 PF10046.4 KEY65450.1 - 0.22 11.6 2.4 3.1 8.0 0.0 3.2 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.6 KEY65450.1 - 0.36 9.4 7.4 0.25 9.9 1.8 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein BTB PF00651.26 KEY65453.1 - 0.00019 21.4 0.0 0.00077 19.4 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Sec2p PF06428.6 KEY65457.1 - 3.8e-22 78.0 19.0 4.9e-22 77.6 10.2 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF4404 PF14357.1 KEY65457.1 - 0.01 16.2 0.7 0.01 16.2 0.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) DUF310 PF03750.8 KEY65457.1 - 0.085 13.0 4.6 0.18 11.9 2.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF310) Med9 PF07544.8 KEY65457.1 - 0.2 11.3 7.9 0.22 11.3 0.2 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF3584 PF12128.3 KEY65457.1 - 0.36 8.1 24.2 0.51 7.6 16.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PMT PF02366.13 KEY65458.1 - 3.1e-76 255.9 16.4 3.1e-76 255.9 11.4 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KEY65458.1 - 4.5e-56 189.4 0.0 6.9e-56 188.8 0.0 1.3 1 0 0 1 1 1 1 MIR domain PRP21_like_P PF12230.3 KEY65459.1 - 7.6e-56 189.1 16.0 7.6e-56 189.1 11.1 1.8 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 KEY65459.1 - 4.8e-36 122.2 0.5 3.5e-17 61.7 0.0 2.5 2 0 0 2 2 2 2 Surp module PX PF00787.19 KEY65460.1 - 8.3e-23 80.3 0.0 1.4e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 PX domain Mito_carr PF00153.22 KEY65461.1 - 9.4e-75 246.4 1.7 2.6e-26 91.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.11 KEY65461.1 - 0.13 12.1 0.0 37 4.3 0.0 3.2 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase CRF PF00473.12 KEY65461.1 - 0.22 11.6 0.2 0.22 11.6 0.1 2.4 3 0 0 3 3 3 0 Corticotropin-releasing factor family Zn_clus PF00172.13 KEY65462.1 - 0.022 14.6 12.6 0.04 13.8 8.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KEY65462.1 - 1.6 8.9 8.4 3.3 7.9 5.9 1.4 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region PQ-loop PF04193.9 KEY65466.1 - 6.4e-19 67.2 1.0 1.3e-13 50.2 0.1 2.4 2 0 0 2 2 2 2 PQ loop repeat eIF3_subunit PF08597.5 KEY65467.1 - 0.00038 20.0 2.2 0.0006 19.4 1.5 1.2 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PBP1_TM PF14812.1 KEY65467.1 - 0.052 13.8 3.9 0.1 12.8 2.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TMA7 PF09072.5 KEY65467.1 - 0.056 13.9 0.2 0.16 12.4 0.2 1.7 1 0 0 1 1 1 0 Translation machinery associated TMA7 MTHFR PF02219.12 KEY65468.1 - 8.7e-102 340.0 0.0 1.2e-101 339.5 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase tRNA-synt_1 PF00133.17 KEY65469.1 - 1.3e-50 172.0 0.0 1.9e-16 59.2 0.0 6.1 3 1 1 4 4 4 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 KEY65469.1 - 1.2e-37 128.9 0.0 2.9e-37 127.7 0.0 1.6 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 KEY65469.1 - 4.2e-30 104.6 0.2 2.7e-22 78.9 0.0 4.3 4 1 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KEY65469.1 - 4.2e-12 46.0 0.0 1.1e-11 44.7 0.0 1.7 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KEY65469.1 - 0.0041 16.2 0.0 0.38 9.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 KEY65469.1 - 0.048 12.4 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (R) tRNA-synt_1c PF00749.16 KEY65469.1 - 0.098 11.3 0.6 7.7 5.0 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain PQ-loop PF04193.9 KEY65470.1 - 2.6e-25 87.7 10.4 2.3e-15 55.8 0.2 3.3 3 0 0 3 3 3 2 PQ loop repeat Mito_carr PF00153.22 KEY65471.1 - 2.5e-73 241.8 1.5 2.3e-25 88.1 0.0 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 KEY65471.1 - 1.2e-17 61.8 6.3 4.6e-06 25.5 0.1 5.4 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 KEY65471.1 - 2e-16 58.3 2.1 2.3e-05 23.8 0.0 6.0 6 0 0 6 6 6 3 EF-hand domain EF-hand_5 PF13202.1 KEY65471.1 - 4.3e-16 57.4 2.9 0.00072 18.7 0.5 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KEY65471.1 - 2.5e-14 53.1 4.8 1e-05 25.5 0.1 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_8 PF13833.1 KEY65471.1 - 1.1e-12 47.2 5.2 0.012 15.1 0.2 5.1 5 0 0 5 5 5 4 EF-hand domain pair EF-hand_9 PF14658.1 KEY65471.1 - 0.031 14.1 0.1 15 5.5 0.0 3.9 4 1 1 5 5 5 0 EF-hand domain Cyclin_N PF00134.18 KEY65472.1 - 4e-42 142.7 0.1 1.6e-41 140.8 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KEY65472.1 - 4.3e-33 113.7 0.1 9.3e-33 112.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Polysacc_synt_4 PF04669.8 KEY65472.1 - 0.14 11.5 0.4 0.96 8.7 0.2 2.2 1 1 0 1 1 1 0 Polysaccharide biosynthesis Pyr_redox PF00070.22 KEY65472.1 - 0.16 12.3 0.2 0.89 10.0 0.1 2.3 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Zn_clus PF00172.13 KEY65474.1 - 0.0006 19.6 12.2 0.0011 18.8 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 KEY65474.1 - 0.062 12.5 0.1 0.062 12.5 0.0 4.1 5 0 0 5 5 5 0 Histone chaperone domain CHZ MFS_1 PF07690.11 KEY65475.1 - 5.3e-27 94.4 46.7 5.3e-27 94.4 32.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KEY65475.1 - 0.00023 20.8 6.6 0.77 9.5 1.5 3.8 3 1 0 3 3 3 2 MFS_1 like family Sugar_tr PF00083.19 KEY65475.1 - 0.00035 19.2 14.2 0.00035 19.2 9.8 3.5 1 1 1 2 2 2 1 Sugar (and other) transporter Abhydrolase_3 PF07859.8 KEY65476.1 - 3e-06 26.9 1.2 0.0091 15.5 0.0 3.2 2 2 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY65476.1 - 0.00036 20.2 0.0 0.0011 18.7 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY65476.1 - 0.00044 20.1 0.2 0.0013 18.6 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 KEY65476.1 - 0.041 13.0 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_1 PF00561.15 KEY65476.1 - 0.046 13.2 0.1 0.26 10.8 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.15 KEY65476.1 - 0.063 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain DUF2235 PF09994.4 KEY65476.1 - 0.079 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) RTA1 PF04479.8 KEY65478.1 - 7.4e-52 176.0 11.4 9.6e-52 175.7 7.9 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF2165 PF09933.4 KEY65478.1 - 0.024 14.3 2.7 0.064 12.9 1.9 2.0 1 1 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) UPF0220 PF05255.6 KEY65478.1 - 0.11 11.7 4.3 0.98 8.6 0.1 2.9 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0220) Amastin PF07344.6 KEY65478.1 - 3.7 7.1 12.1 2.4 7.7 0.3 2.9 1 1 2 3 3 3 0 Amastin surface glycoprotein DUF996 PF06195.8 KEY65478.1 - 8.5 6.3 18.7 1.5 8.8 7.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF996) RNA_pol_Rpc4 PF05132.9 KEY65479.1 - 2e-22 79.5 0.3 2e-20 73.1 0.0 3.2 3 0 0 3 3 3 1 RNA polymerase III RPC4 UreD PF01774.12 KEY65480.1 - 2e-53 180.9 0.0 2.4e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein STAG PF08514.6 KEY65481.1 - 3e-27 94.6 1.0 9.2e-27 93.0 0.7 1.9 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.1 KEY65481.1 - 0.00014 22.1 1.1 0.014 15.6 0.0 4.1 2 1 3 5 5 5 4 HEAT repeats HEAT PF02985.17 KEY65481.1 - 0.0022 17.9 0.0 7.1 6.9 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat DUF422 PF04240.7 KEY65481.1 - 0.084 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF422) POT1 PF02765.12 KEY65482.1 - 1.2e-08 35.0 0.0 2.3e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Arm PF00514.18 KEY65483.1 - 2.4e-95 309.5 14.6 3.9e-14 51.8 0.1 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KEY65483.1 - 1.8e-24 85.8 0.1 2.3e-09 37.4 0.0 5.9 1 1 6 7 7 7 6 HEAT repeats IBB PF01749.15 KEY65483.1 - 7.9e-23 80.4 2.1 1.4e-22 79.6 1.5 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 KEY65483.1 - 3.8e-22 78.1 7.9 2.8e-09 37.1 0.1 5.9 4 1 2 6 6 6 3 HEAT-like repeat HEAT PF02985.17 KEY65483.1 - 6.8e-21 72.4 0.4 1.7e-05 24.5 0.0 6.9 6 0 0 6 6 6 4 HEAT repeat Arm_2 PF04826.8 KEY65483.1 - 3.3e-10 39.5 0.0 0.0049 15.9 0.0 4.1 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 KEY65483.1 - 5.5e-06 24.9 0.0 0.00058 18.3 0.0 2.3 1 1 0 2 2 2 2 Adaptin N terminal region HEAT_PBS PF03130.11 KEY65483.1 - 0.00034 20.7 0.2 1.4 9.6 0.0 4.5 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 KEY65483.1 - 0.00092 19.1 0.0 2.8 7.8 0.0 4.3 2 1 2 5 5 5 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 KEY65483.1 - 0.002 16.4 0.1 0.58 8.3 0.0 2.8 2 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit Glycos_trans_3N PF02885.12 KEY65483.1 - 0.013 15.0 0.0 18 5.0 0.0 3.5 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain RICTOR_V PF14668.1 KEY65483.1 - 0.021 14.7 6.2 4.7 7.2 0.1 5.0 3 2 3 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 Mo25 PF08569.6 KEY65483.1 - 0.086 11.8 0.0 1.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Mo25-like HA2 PF04408.18 KEY65484.1 - 3.8e-18 65.4 0.1 3.8e-18 65.4 0.1 1.9 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KEY65484.1 - 9.9e-16 57.5 0.0 2.7e-15 56.2 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KEY65484.1 - 4.3e-15 55.3 0.0 1.2e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIT PF01230.18 KEY65484.1 - 2.1e-14 53.7 0.0 6.1e-14 52.3 0.0 1.8 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KEY65484.1 - 5.6e-13 49.1 4.2 8.5e-12 45.3 2.9 2.5 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DEAD PF00270.24 KEY65484.1 - 2.6e-10 40.0 0.1 1e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase RWD PF05773.17 KEY65484.1 - 5.1e-06 26.3 0.0 9.6e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 RWD domain UBA PF00627.26 KEY65484.1 - 7.8e-06 25.5 0.1 0.018 14.8 0.0 3.1 2 0 0 2 2 2 2 UBA/TS-N domain AAA_22 PF13401.1 KEY65484.1 - 1.5e-05 25.0 0.1 4.4e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain DND1_DSRM PF14709.1 KEY65484.1 - 0.00027 21.1 0.3 0.00088 19.5 0.2 2.0 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_29 PF13555.1 KEY65484.1 - 0.0027 17.1 0.0 0.0069 15.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain KaiC PF06745.8 KEY65484.1 - 0.0031 16.6 0.2 0.0079 15.3 0.1 1.7 1 1 0 1 1 1 1 KaiC ResIII PF04851.10 KEY65484.1 - 0.015 15.1 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KEY65484.1 - 0.022 14.5 0.5 0.54 10.0 0.0 3.2 3 0 0 3 3 3 0 Part of AAA domain AAA_25 PF13481.1 KEY65484.1 - 0.025 13.9 0.0 0.066 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KEY65484.1 - 0.032 14.5 0.1 0.032 14.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KEY65484.1 - 0.075 11.9 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 KEY65484.1 - 0.076 12.4 0.2 0.61 9.4 0.0 2.4 2 1 0 3 3 3 0 AAA-like domain AT_hook PF02178.14 KEY65485.1 - 0.024 14.2 45.2 0.045 13.4 3.2 5.0 4 0 0 4 4 4 0 AT hook motif CDC27 PF09507.5 KEY65485.1 - 0.77 8.9 10.4 0.85 8.7 7.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Cwf_Cwc_15 PF04889.7 KEY65485.1 - 2.3 7.8 9.9 3.1 7.4 6.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MSP1_C PF07462.6 KEY65485.1 - 2.7 6.2 8.3 3.2 6.0 5.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Nop14 PF04147.7 KEY65485.1 - 3 5.6 9.8 3 5.6 6.8 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.9 KEY65485.1 - 3.3 7.1 8.1 4.2 6.8 5.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Kinesin PF00225.18 KEY65486.1 - 2.6e-115 384.7 0.0 4.6e-115 383.9 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF2018 PF09442.5 KEY65486.1 - 0.099 13.2 7.5 0.045 14.3 2.8 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF2018) DUF3395 PF11875.3 KEY65486.1 - 0.12 12.0 3.9 0.14 11.8 1.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3395) DUF87 PF01935.12 KEY65486.1 - 0.62 9.8 0.0 0.62 9.8 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function DUF87 SOG2 PF10428.4 KEY65487.1 - 0.57 8.7 6.9 0.57 8.7 4.8 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Adhesin_P1 PF03257.8 KEY65488.1 - 0.054 13.8 0.4 0.054 13.8 0.3 1.9 2 0 0 2 2 2 0 Mycoplasma adhesin P1 MFS_1 PF07690.11 KEY65489.1 - 1e-20 73.7 44.4 9.8e-20 70.5 30.0 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1484 PF07363.6 KEY65491.1 - 0.0053 17.0 1.3 0.01 16.1 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1484) Prefoldin_3 PF13758.1 KEY65491.1 - 0.03 14.0 3.7 0.24 11.1 0.3 2.7 2 1 0 2 2 2 0 Prefoldin subunit HSBP1 PF06825.7 KEY65491.1 - 0.037 13.5 1.0 0.61 9.6 0.4 2.7 2 1 0 2 2 2 0 Heat shock factor binding protein 1 Fib_alpha PF08702.5 KEY65491.1 - 0.081 13.0 5.2 0.54 10.3 0.2 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.7 KEY65491.1 - 3 7.6 6.0 9.3 6.0 3.0 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2235 PF09994.4 KEY65493.1 - 1e-42 146.4 0.0 1.4e-42 146.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) TPR_10 PF13374.1 KEY65494.1 - 4.2e-95 309.3 0.1 4.6e-12 45.4 0.0 8.6 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.1 KEY65494.1 - 6.2e-64 211.9 2.8 1.1e-14 54.0 0.0 5.4 2 1 3 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 KEY65494.1 - 2.2e-20 70.7 3.9 0.062 13.1 0.0 7.9 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 KEY65494.1 - 1.3e-14 53.5 0.8 0.0017 17.9 0.0 5.3 3 2 0 4 4 4 4 TPR repeat TPR_17 PF13431.1 KEY65494.1 - 1.9e-14 52.5 0.0 1.2 9.5 0.0 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_4 PF07721.9 KEY65494.1 - 6.4e-12 44.6 1.3 0.073 13.5 0.0 7.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEY65494.1 - 2.3e-10 39.6 0.0 0.25 11.0 0.1 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEY65494.1 - 4.2e-10 38.7 6.3 0.035 14.0 0.1 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEY65494.1 - 2.7e-09 37.4 0.2 6.3 7.5 0.0 6.4 2 2 4 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KEY65494.1 - 5.4e-06 26.5 1.8 92 4.1 0.0 7.2 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 KEY65494.1 - 1e-05 25.7 0.4 1.2 9.5 0.0 5.3 3 2 4 7 7 7 1 Tetratricopeptide repeat TPR_3 PF07720.7 KEY65494.1 - 5.1e-05 22.9 0.0 0.14 12.0 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEY65494.1 - 9.6e-05 21.9 0.1 30 4.7 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Trans_reg_C PF00486.23 KEY65494.1 - 0.0025 17.7 0.1 6.3 6.7 0.0 3.8 3 1 0 3 3 3 1 Transcriptional regulatory protein, C terminal TPR_6 PF13174.1 KEY65494.1 - 0.076 13.5 4.1 82 3.9 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat NdhL PF10716.4 KEY65494.1 - 1.9 8.3 3.4 14 5.5 0.0 2.9 3 0 0 3 3 3 0 NADH dehydrogenase transmembrane subunit Tyrosinase PF00264.15 KEY65496.1 - 7.7e-31 107.9 7.5 7.7e-31 107.9 5.2 1.7 2 0 0 2 2 2 1 Common central domain of tyrosinase RskA PF10099.4 KEY65496.1 - 0.042 13.5 1.1 0.065 12.9 0.8 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Glyco_hydro_61 PF03443.9 KEY65497.1 - 1.4e-41 142.7 0.0 1.7e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KEY65497.1 - 3.9e-11 42.3 13.8 1.3e-10 40.7 9.6 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KEY65497.1 - 0.11 12.5 7.8 0.32 11.0 5.4 1.9 1 1 0 1 1 1 0 Toxin 7 WSC PF01822.14 KEY65498.1 - 0.0074 16.1 5.2 0.011 15.6 3.6 1.3 1 0 0 1 1 1 1 WSC domain PCMT PF01135.14 KEY65499.1 - 5.9e-44 150.1 0.0 7.8e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KEY65499.1 - 5.9e-06 25.9 0.0 8.8e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY65499.1 - 4.5e-05 24.0 0.0 7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY65499.1 - 0.0002 21.3 0.0 0.00028 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KEY65499.1 - 0.0016 18.1 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KEY65499.1 - 0.0017 17.4 0.0 0.002 17.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KEY65499.1 - 0.005 16.5 0.0 0.0066 16.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain DUF3248 PF11609.3 KEY65499.1 - 0.072 12.7 0.1 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3248) RrnaAD PF00398.15 KEY65499.1 - 0.094 11.7 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 KEY65499.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF2370 PF10176.4 KEY65500.1 - 4.7e-84 281.3 0.0 7.4e-84 280.7 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) Mito_carr PF00153.22 KEY65502.1 - 3.7e-56 186.8 5.0 1.3e-23 82.4 0.3 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Ank_2 PF12796.2 KEY65504.1 - 3e-36 123.6 1.1 3e-17 62.7 0.1 3.6 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEY65504.1 - 1.6e-19 68.0 0.7 3.7e-05 23.5 0.3 6.5 5 1 1 6 6 6 3 Ankyrin repeat Ank PF00023.25 KEY65504.1 - 9.4e-19 66.2 1.4 3.4e-06 26.5 0.7 6.5 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 KEY65504.1 - 6.7e-17 61.1 0.9 9.1e-09 35.2 0.4 5.0 1 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEY65504.1 - 4.2e-16 58.9 0.7 7.3e-07 29.5 0.1 5.5 3 2 3 6 6 6 4 Ankyrin repeats (many copies) adh_short PF00106.20 KEY65505.1 - 7.1e-29 100.8 3.1 8.5e-29 100.6 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY65505.1 - 1.4e-15 57.7 0.4 1.6e-15 57.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY65505.1 - 8.8e-15 54.8 1.0 1.1e-14 54.4 0.7 1.1 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 KEY65505.1 - 0.008 16.5 0.5 0.02 15.3 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent HTH_32 PF13565.1 KEY65506.1 - 0.059 14.1 0.1 0.36 11.6 0.1 2.4 2 1 0 2 2 2 0 Homeodomain-like domain DUF2746 PF10874.3 KEY65506.1 - 0.084 13.0 0.2 6.4 7.0 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2746) PSD4 PF07631.6 KEY65506.1 - 0.29 11.5 1.9 0.46 10.8 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1592) DUF2654 PF10849.3 KEY65506.1 - 0.38 10.5 2.9 1.5 8.6 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2654) DUF1664 PF07889.7 KEY65506.1 - 4.9 6.9 7.5 0.23 11.2 0.6 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) zf-C2H2_4 PF13894.1 KEY65507.1 - 3.2e-07 30.2 24.7 0.071 13.4 1.2 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY65507.1 - 0.00043 20.4 26.7 0.0096 16.2 1.9 5.1 5 0 0 5 5 5 3 Zinc finger, C2H2 type DUF1796 PF08795.5 KEY65507.1 - 0.029 13.9 1.4 3.4 7.2 0.1 2.3 2 0 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) DUF4238 PF14022.1 KEY65508.1 - 5.6e-30 104.5 1.3 5.6e-30 104.5 0.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4238) Pkinase PF00069.20 KEY65509.1 - 1.7e-07 30.6 0.0 7.3e-07 28.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KEY65509.1 - 0.00038 19.5 0.0 0.00056 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEY65509.1 - 0.0017 17.4 0.1 0.003 16.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KEY65509.1 - 0.006 15.9 0.1 0.0093 15.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KEY65509.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 KEY65509.1 - 0.015 15.0 0.2 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KEY65509.1 - 0.076 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Seadorna_VP7 PF07387.6 KEY65509.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Coq4 PF05019.8 KEY65511.1 - 1.7e-95 318.1 0.0 2e-95 317.9 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 dsDNA_bind PF01984.15 KEY65512.1 - 2.3e-35 120.7 9.2 2.9e-35 120.4 6.4 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 KEY65512.1 - 0.034 14.3 2.4 0.087 13.0 1.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) Host_attach PF10116.4 KEY65512.1 - 0.48 10.6 5.6 1.8 8.8 3.9 1.8 1 1 0 1 1 1 0 Protein required for attachment to host cells FlgM PF04316.8 KEY65512.1 - 3.3 7.7 5.9 7 6.6 0.1 2.6 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM ApbA_C PF08546.6 KEY65513.1 - 1.2e-15 57.6 0.0 2.6e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KEY65513.1 - 2.1e-12 46.7 0.0 3.3e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sas10_Utp3 PF04000.10 KEY65514.1 - 8.2e-15 54.7 0.1 1.7e-14 53.7 0.1 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF2076 PF09849.4 KEY65515.1 - 2.1e-08 34.5 9.5 2.5e-08 34.2 6.6 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 KEY65515.1 - 0.00017 21.3 3.4 0.00027 20.7 2.3 1.3 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 KEY65515.1 - 0.017 15.2 1.3 0.038 14.1 0.7 1.7 1 1 0 1 1 1 0 GCK domain COX6B PF02297.12 KEY65515.1 - 0.092 12.7 2.3 0.13 12.2 1.6 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb DUF605 PF04652.11 KEY65515.1 - 0.15 11.4 8.5 0.17 11.2 5.9 1.1 1 0 0 1 1 1 0 Vta1 like UBX PF00789.15 KEY65516.1 - 5.7e-14 51.9 0.0 1.3e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 UBX domain Asp-B-Hydro_N PF05279.6 KEY65516.1 - 6.1 6.6 13.8 11 5.7 9.6 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Aldo_ket_red PF00248.16 KEY65517.1 - 1.2e-56 191.6 0.0 1.4e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Homeobox_KN PF05920.6 KEY65517.1 - 0.0069 16.0 0.0 0.019 14.6 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain PGAP1 PF07819.8 KEY65518.1 - 4e-07 29.8 0.0 9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KEY65518.1 - 1.2e-06 27.9 0.0 2.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KEY65518.1 - 2.8e-06 27.3 0.3 2e-05 24.6 0.0 2.6 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY65518.1 - 0.00034 20.4 0.2 0.0072 16.0 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family WD40 PF00400.27 KEY65518.1 - 0.00084 19.1 0.1 0.19 11.7 0.0 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat 6PF2K PF01591.13 KEY65518.1 - 0.0021 17.1 0.0 0.0081 15.2 0.0 1.8 2 0 0 2 2 2 1 6-phosphofructo-2-kinase Abhydrolase_1 PF00561.15 KEY65518.1 - 0.0038 16.8 0.0 0.0084 15.6 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF3312 PF11768.3 KEY65518.1 - 0.0079 14.4 0.0 0.015 13.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) NB-ARC PF00931.17 KEY65518.1 - 0.014 14.2 0.1 0.12 11.1 0.1 2.3 1 1 0 1 1 1 0 NB-ARC domain DUF2974 PF11187.3 KEY65518.1 - 0.047 13.0 0.1 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) APS_kinase PF01583.15 KEY65518.1 - 0.071 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase PQQ_2 PF13360.1 KEY65518.1 - 0.12 11.8 0.4 3.3 7.0 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain DUF900 PF05990.7 KEY65518.1 - 0.13 11.5 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) RasGAP_C PF03836.10 KEY65520.1 - 0.00044 19.9 3.2 0.00073 19.2 2.2 1.3 1 0 0 1 1 1 1 RasGAP C-terminus DUF1875 PF08961.5 KEY65520.1 - 0.066 12.5 1.1 0.16 11.2 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1875) DivIC PF04977.10 KEY65520.1 - 0.086 12.3 3.6 0.18 11.2 2.5 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF972 PF06156.8 KEY65520.1 - 0.15 12.4 4.6 0.14 12.5 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 KEY65520.1 - 0.32 10.5 5.0 0.6 9.6 3.5 1.4 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 KEY65520.1 - 9.8 6.5 11.1 3.9 7.8 5.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF904) SURF1 PF02104.10 KEY65522.1 - 2.5e-66 223.5 0.0 3.2e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 SURF1 family CENP-T PF15511.1 KEY65523.1 - 1.5e-104 350.5 25.1 1.5e-104 350.5 17.4 2.6 3 1 0 3 3 3 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 KEY65523.1 - 3.5e-07 30.2 0.0 6.3e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 KEY65523.1 - 4.9e-07 29.7 0.0 1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KEY65523.1 - 0.0025 17.8 0.0 0.0055 16.7 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF531 PF04407.7 KEY65523.1 - 0.15 11.9 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF531) CblD PF07434.6 KEY65524.1 - 0.058 12.0 0.0 0.073 11.7 0.0 1.1 1 0 0 1 1 1 0 CblD like pilus biogenesis initiator Cu-oxidase_2 PF07731.9 KEY65525.1 - 1.1e-23 83.3 4.5 2.6e-21 75.5 1.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KEY65525.1 - 2e-23 82.3 0.2 5.7e-23 80.8 0.1 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 KEY65525.1 - 0.00062 19.7 0.0 0.1 12.5 0.0 2.9 3 1 0 3 3 3 1 Multicopper oxidase Amidase PF01425.16 KEY65526.1 - 1.8e-92 310.5 0.0 4.5e-92 309.1 0.0 1.6 2 0 0 2 2 2 1 Amidase RNase_H PF00075.19 KEY65527.1 - 1.3e-13 51.4 0.0 2.2e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 RNase H F-box-like PF12937.2 KEY65527.1 - 8.1e-07 28.6 0.4 2e-06 27.4 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEY65527.1 - 0.0035 16.9 0.2 0.012 15.2 0.1 2.0 1 0 0 1 1 1 1 F-box domain RVT_3 PF13456.1 KEY65527.1 - 0.041 13.6 0.0 8 6.3 0.0 2.8 3 0 0 3 3 3 0 Reverse transcriptase-like Fungal_trans PF04082.13 KEY65529.1 - 2.1e-12 46.5 0.1 3.6e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY65529.1 - 3.5e-07 30.0 9.6 5.4e-07 29.4 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FlxA PF14282.1 KEY65529.1 - 0.042 13.7 2.0 0.082 12.8 1.4 1.4 1 0 0 1 1 1 0 FlxA-like protein Surfac_D-trimer PF09006.6 KEY65529.1 - 0.059 13.1 0.1 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation MFS_1 PF07690.11 KEY65530.1 - 5.1e-33 114.2 77.6 1.5e-25 89.7 27.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KEY65530.1 - 7.6e-06 25.6 4.8 0.00088 19.0 1.4 3.3 3 0 0 3 3 3 2 MFS_1 like family Sugar_tr PF00083.19 KEY65530.1 - 3.4e-05 22.6 41.3 0.029 12.9 6.0 3.5 2 2 1 3 3 3 3 Sugar (and other) transporter TraT PF05818.7 KEY65530.1 - 3.7 6.9 5.6 1.3 8.3 1.2 2.1 2 1 0 2 2 2 0 Enterobacterial TraT complement resistance protein HET PF06985.6 KEY65531.1 - 1e-20 74.3 2.3 1e-20 74.3 0.0 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) PPP4R2 PF09184.6 KEY65531.1 - 1.6 8.2 23.6 2.2 7.7 16.3 1.2 1 0 0 1 1 1 0 PPP4R2 PBP_sp32 PF07222.7 KEY65531.1 - 3.9 6.5 11.1 7.6 5.6 7.7 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DDE_Tnp_1_3 PF13612.1 KEY65532.1 - 0.025 14.3 0.3 1.7 8.3 0.1 2.3 2 0 0 2 2 2 0 Transposase DDE domain OspD PF03207.8 KEY65532.1 - 0.2 10.7 3.9 0.33 10.0 2.7 1.3 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) TPR_MLP1_2 PF07926.7 KEY65532.1 - 0.32 10.7 5.1 0.18 11.5 1.3 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Latarcin PF10279.4 KEY65532.1 - 1.6 8.9 6.2 0.69 10.1 1.6 2.4 2 0 0 2 2 2 0 Latarcin precursor AAA PF00004.24 KEY65533.1 - 2.1e-16 60.2 0.0 1e-15 58.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEY65533.1 - 0.0002 22.1 0.0 0.0002 22.1 0.0 4.2 4 1 0 4 4 3 1 AAA domain AAA_18 PF13238.1 KEY65533.1 - 0.00033 20.9 0.6 0.0041 17.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEY65533.1 - 0.00057 20.0 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEY65533.1 - 0.0011 18.7 0.0 0.0027 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KEY65533.1 - 0.0023 17.6 0.0 0.0071 16.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KEY65533.1 - 0.0044 16.9 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEY65533.1 - 0.0059 16.6 0.1 0.022 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain CPT PF07931.7 KEY65533.1 - 0.034 13.7 0.0 0.077 12.6 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 KEY65533.1 - 0.048 13.5 0.0 0.19 11.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KEY65533.1 - 0.078 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Torsin PF06309.6 KEY65533.1 - 0.16 11.8 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Torsin PAN_4 PF14295.1 KEY65535.1 - 0.0043 16.7 0.2 0.012 15.2 0.1 1.8 1 0 0 1 1 1 1 PAN domain Pkinase PF00069.20 KEY65536.1 - 3.3e-19 69.0 0.0 4.6e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY65536.1 - 4.9e-12 45.4 0.0 9.3e-12 44.5 0.0 1.5 1 1 1 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 KEY65536.1 - 3.3e-06 26.3 0.0 4.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEY65536.1 - 0.0029 17.3 0.0 0.0096 15.6 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KEY65536.1 - 0.038 13.3 0.0 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 KEY65536.1 - 0.041 12.6 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 KEY65537.1 - 2.2e-24 86.0 0.0 3e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY65537.1 - 1.9e-19 69.7 0.0 3.4e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 KEY65537.1 - 0.0087 15.6 0.1 0.027 14.0 0.0 1.7 1 1 1 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 KEY65537.1 - 0.048 13.3 0.2 0.11 12.2 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.2 KEY65538.1 - 7.9e-12 45.3 0.0 2.7e-11 43.6 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEY65538.1 - 2.6e-09 37.0 0.1 6.8e-05 22.9 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KEY65538.1 - 6.1e-09 35.2 0.0 0.00038 20.1 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat PNP_UDP_1 PF01048.15 KEY65538.1 - 1.2e-08 34.2 0.2 9.2e-08 31.3 0.1 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.1 KEY65538.1 - 3e-08 33.8 0.2 2.1e-07 31.0 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain Ank_4 PF13637.1 KEY65538.1 - 3.9e-07 30.4 0.0 8.9e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY65538.1 - 2.9e-06 26.9 0.0 0.16 12.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat NACHT PF05729.7 KEY65538.1 - 3.8e-05 23.3 0.0 8.7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KEY65538.1 - 0.0006 19.9 0.0 0.002 18.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_10 PF12846.2 KEY65538.1 - 0.0023 17.4 0.0 0.033 13.6 0.0 2.8 1 1 0 1 1 1 1 AAA-like domain AAA PF00004.24 KEY65538.1 - 0.0099 16.0 0.0 0.04 14.1 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KEY65538.1 - 0.038 13.8 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Mur_ligase PF01225.20 KEY65538.1 - 0.039 14.0 0.9 1.4 9.0 0.0 2.6 2 0 0 2 2 2 0 Mur ligase family, catalytic domain KAP_NTPase PF07693.9 KEY65538.1 - 0.067 12.1 0.0 2.3 7.1 0.1 2.4 1 1 0 2 2 2 0 KAP family P-loop domain Sigma54_activ_2 PF14532.1 KEY65538.1 - 0.12 12.4 0.0 0.56 10.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 KEY65538.1 - 0.12 12.0 0.0 0.36 10.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Peptidase_C48 PF02902.14 KEY65539.1 - 0.0015 18.1 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Thiolase_N PF00108.18 KEY65541.1 - 1.3e-90 302.9 0.7 1.3e-90 302.9 0.5 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KEY65541.1 - 5.9e-38 129.0 1.2 5.9e-38 129.0 0.9 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KEY65541.1 - 0.0013 18.3 0.9 0.0091 15.4 0.7 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain UQ_con PF00179.21 KEY65542.1 - 5e-52 175.0 0.1 5.6e-52 174.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEY65542.1 - 1.6e-06 27.9 0.0 1.8e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KEY65542.1 - 0.0071 16.2 0.2 0.014 15.2 0.1 1.6 1 1 0 1 1 1 1 RWD domain Kinesin PF00225.18 KEY65543.1 - 9.5e-114 379.5 0.3 9.5e-114 379.5 0.2 1.9 2 0 0 2 2 2 1 Kinesin motor domain AAA_10 PF12846.2 KEY65543.1 - 0.22 10.9 0.1 0.22 10.9 0.0 3.0 2 1 0 2 2 2 0 AAA-like domain LCM PF04072.9 KEY65545.1 - 1.1e-22 80.4 0.0 1.9e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF3570 PF12094.3 KEY65545.1 - 0.15 10.7 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3570) TFIID-18kDa PF02269.11 KEY65546.1 - 5.3e-30 103.0 2.6 1.2e-29 101.9 0.1 2.4 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit Myc_N PF01056.13 KEY65546.1 - 0.064 12.4 0.9 0.11 11.6 0.6 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Clat_adaptor_s PF01217.15 KEY65547.1 - 9e-56 187.5 1.8 9.9e-56 187.3 1.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-CCHC_2 PF13696.1 KEY65548.1 - 0.51 9.8 3.7 1.4 8.5 2.5 1.7 1 0 0 1 1 1 0 Zinc knuckle Ist1 PF03398.9 KEY65549.1 - 3.8e-64 215.0 0.3 5e-64 214.6 0.2 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Sigma70_ner PF04546.8 KEY65549.1 - 0.47 10.0 2.9 0.42 10.1 0.2 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region PDZ_1 PF12812.2 KEY65550.1 - 2.3e-57 190.7 0.1 1.6e-34 117.6 0.0 2.7 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 KEY65550.1 - 1.2e-15 57.1 0.4 4.4e-07 29.7 0.1 4.4 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.1 KEY65550.1 - 6.1e-14 52.0 0.3 4.9e-12 45.8 0.0 2.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ PF00595.19 KEY65550.1 - 1.1e-07 31.9 0.0 0.00072 19.6 0.0 3.9 4 0 0 4 4 4 2 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 KEY65550.1 - 0.00024 20.7 0.0 0.00067 19.3 0.0 1.7 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.1 KEY65550.1 - 0.0021 17.8 0.6 0.14 11.9 0.1 3.5 4 0 0 4 4 4 1 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 KEY65550.1 - 0.19 11.1 0.2 0.39 10.1 0.2 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.4 KEY65550.1 - 0.39 9.0 0.1 0.84 7.9 0.1 1.4 2 0 0 2 2 2 0 Peptidase S46 Myb_DNA-binding PF00249.26 KEY65551.1 - 0.047 13.7 1.4 0.11 12.5 0.3 2.1 2 1 0 2 2 2 0 Myb-like DNA-binding domain DnaJ PF00226.26 KEY65552.1 - 2.8e-22 78.2 1.8 5.3e-22 77.3 1.3 1.5 1 0 0 1 1 1 1 DnaJ domain DUF663 PF04950.7 KEY65553.1 - 2.4e-88 295.9 0.0 2.4e-88 295.9 0.0 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KEY65553.1 - 1.2e-27 95.2 0.0 8.3e-26 89.3 0.0 2.5 2 0 0 2 2 2 1 AARP2CN (NUC121) domain AAA_22 PF13401.1 KEY65553.1 - 3.5e-06 27.1 0.1 1.3e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEY65553.1 - 3.7e-06 27.0 0.0 1.6e-05 24.9 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.22 KEY65553.1 - 7.8e-06 25.4 0.0 0.0036 16.7 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 KEY65553.1 - 5.2e-05 24.0 0.0 5.2e-05 24.0 0.0 4.5 2 1 1 3 3 2 1 AAA domain NACHT PF05729.7 KEY65553.1 - 9e-05 22.1 0.1 0.00033 20.3 0.0 2.1 2 1 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.18 KEY65553.1 - 0.00015 21.6 0.0 0.00043 20.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEY65553.1 - 0.00018 21.9 0.0 0.00068 20.1 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 KEY65553.1 - 0.00029 21.1 0.3 0.0011 19.2 0.0 2.1 2 0 0 2 2 1 1 ABC transporter AAA PF00004.24 KEY65553.1 - 0.00042 20.5 0.0 0.0012 19.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEY65553.1 - 0.0006 19.5 0.1 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KEY65553.1 - 0.00063 19.6 0.0 0.0022 17.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KEY65553.1 - 0.0012 18.5 0.0 0.0035 17.0 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KEY65553.1 - 0.0012 18.2 0.0 0.0037 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KEY65553.1 - 0.0021 17.5 0.0 0.0065 15.9 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 KEY65553.1 - 0.0024 18.1 0.0 0.0024 18.1 0.0 4.4 3 2 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KEY65553.1 - 0.0024 17.3 1.3 0.0065 15.9 0.0 2.3 3 0 0 3 3 3 1 AAA-like domain AAA_28 PF13521.1 KEY65553.1 - 0.0046 16.9 0.9 0.01 15.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 KEY65553.1 - 0.0057 16.5 0.1 0.018 14.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain DUF258 PF03193.11 KEY65553.1 - 0.0099 15.0 0.0 0.026 13.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NTPase_1 PF03266.10 KEY65553.1 - 0.011 15.4 0.1 0.024 14.3 0.1 1.6 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.1 KEY65553.1 - 0.013 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KEY65553.1 - 0.016 14.0 0.0 0.032 13.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 KEY65553.1 - 0.018 15.2 0.0 0.05 13.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase cobW PF02492.14 KEY65553.1 - 0.028 13.8 0.0 0.057 12.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 KEY65553.1 - 0.074 13.0 1.2 0.64 9.9 0.0 2.7 2 1 1 3 3 3 0 AAA domain AAA_23 PF13476.1 KEY65553.1 - 0.42 10.9 0.0 0.42 10.9 0.0 4.0 3 1 0 3 3 2 0 AAA domain DASH_Ask1 PF08655.5 KEY65555.1 - 1.5e-24 85.5 0.1 2.6e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 Spc97_Spc98 PF04130.8 KEY65556.1 - 4.3e-65 220.0 0.0 5.7e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Eaf7 PF07904.8 KEY65557.1 - 2e-26 91.7 0.1 2e-26 91.7 0.1 1.7 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 Sporozoite_P67 PF05642.6 KEY65557.1 - 0.034 12.0 4.0 0.054 11.3 2.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC27 PF09507.5 KEY65557.1 - 0.38 9.9 15.8 0.0086 15.3 6.4 1.5 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 NOA36 PF06524.7 KEY65557.1 - 1.7 7.8 6.6 3 7.0 4.6 1.4 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 KEY65557.1 - 5.3 4.9 6.8 7.3 4.5 4.7 1.2 1 0 0 1 1 1 0 CDC45-like protein API5 PF05918.6 KEY65557.1 - 8.2 4.7 8.1 10 4.4 5.6 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) FAM176 PF14851.1 KEY65557.1 - 8.8 5.9 7.7 2.7 7.6 3.0 1.8 2 0 0 2 2 2 0 FAM176 family ResIII PF04851.10 KEY65559.1 - 4.6e-21 75.4 0.0 9.4e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KEY65559.1 - 4.4e-14 52.0 0.0 1e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEY65559.1 - 9.8e-11 41.4 0.0 1.8e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 KEY65559.1 - 0.081 11.7 0.1 0.22 10.2 0.0 1.6 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.1 KEY65559.1 - 0.21 11.6 0.9 1.1 9.4 0.2 2.5 2 1 1 3 3 3 0 AAA domain KH_3 PF13014.1 KEY65560.1 - 6.2e-26 89.5 1.9 9.5e-06 25.1 0.0 5.8 5 0 0 5 5 5 5 KH domain KH_1 PF00013.24 KEY65560.1 - 2.8e-25 87.7 3.0 1.3e-07 31.1 0.2 6.7 7 0 0 7 7 7 5 KH domain FAD_binding_4 PF01565.18 KEY65561.1 - 8.6e-25 86.8 1.7 2.1e-24 85.5 1.0 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KEY65561.1 - 1.9e-07 30.9 0.0 3.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like LEM PF03020.10 KEY65561.1 - 0.043 13.2 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 LEM domain Pribosyltran PF00156.22 KEY65562.1 - 3.2e-16 59.2 0.8 5.2e-16 58.5 0.6 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain HAD_2 PF13419.1 KEY65564.1 - 4e-33 115.1 0.4 4.8e-33 114.8 0.2 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEY65564.1 - 2.2e-07 31.5 0.0 4.9e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEY65564.1 - 8.3e-07 28.6 0.0 1.6e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 KEY65564.1 - 0.066 13.3 0.0 0.085 13.0 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Med21 PF11221.3 KEY65565.1 - 1.7e-38 131.8 5.3 1.9e-38 131.6 3.7 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Spore_III_AB PF09548.5 KEY65565.1 - 0.0057 16.4 1.7 0.0057 16.4 1.1 1.3 2 0 0 2 2 2 1 Stage III sporulation protein AB (spore_III_AB) Med9 PF07544.8 KEY65565.1 - 0.015 15.0 0.1 0.015 15.0 0.1 3.1 2 1 2 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 TMCO5 PF14992.1 KEY65565.1 - 0.016 14.3 3.4 0.018 14.2 2.3 1.2 1 0 0 1 1 1 0 TMCO5 family DUF4455 PF14643.1 KEY65565.1 - 0.021 13.4 4.0 0.017 13.7 2.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4455) GAS PF13851.1 KEY65565.1 - 0.093 11.9 7.9 0.5 9.5 0.1 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Phi-29_GP16_7 PF06720.6 KEY65565.1 - 0.095 12.3 0.5 0.2 11.3 0.3 1.5 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 YjcZ PF13990.1 KEY65565.1 - 0.25 10.4 2.9 0.19 10.8 0.8 1.6 1 1 1 2 2 2 0 YjcZ-like protein Fib_alpha PF08702.5 KEY65565.1 - 0.28 11.3 1.6 0.82 9.7 1.0 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1843 PF08898.5 KEY65565.1 - 0.35 10.9 5.1 0.34 10.9 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) CENP-Q PF13094.1 KEY65565.1 - 0.41 10.6 9.2 0.23 11.4 4.6 1.7 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit APG6 PF04111.7 KEY65565.1 - 1 8.3 6.2 1.4 7.9 4.3 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 Sec62 PF03839.11 KEY65566.1 - 4e-52 176.8 0.5 4e-52 176.8 0.3 1.4 2 0 0 2 2 2 1 Translocation protein Sec62 Ribonuclease_T2 PF00445.13 KEY65567.1 - 2.7e-31 108.6 0.0 3.9e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Acetyltransf_1 PF00583.19 KEY65568.1 - 8.6e-08 32.1 0.1 1.4e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEY65568.1 - 5.2e-07 29.7 0.0 9.2e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEY65568.1 - 1e-06 28.3 0.1 2.1e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KEY65568.1 - 1.2e-06 28.5 0.0 1.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEY65568.1 - 0.019 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KEY65568.1 - 0.025 14.4 0.1 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PLDc PF00614.17 KEY65569.1 - 3.6e-15 55.2 3.1 3.1e-08 33.1 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KEY65569.1 - 6e-13 48.6 0.0 1.3e-05 24.9 0.0 3.6 3 1 0 3 3 3 2 PLD-like domain Regulator_TrmB PF11495.3 KEY65569.1 - 0.076 11.9 0.3 0.21 10.5 0.0 1.8 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB Thioredoxin PF00085.15 KEY65570.1 - 3e-39 132.8 0.1 2.7e-24 84.8 0.0 3.5 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 KEY65570.1 - 3.3e-12 46.5 0.0 6.9e-06 25.9 0.0 3.6 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KEY65570.1 - 1.1e-09 38.3 0.4 0.00019 21.4 0.0 4.3 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KEY65570.1 - 1e-06 28.9 2.1 0.005 17.0 0.0 4.5 4 1 0 4 4 4 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KEY65570.1 - 2.6e-05 24.1 0.4 0.0015 18.5 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KEY65570.1 - 0.00016 21.2 0.6 0.22 11.0 0.0 3.3 3 1 0 3 3 3 2 Thioredoxin HyaE PF07449.6 KEY65570.1 - 0.0032 17.3 0.0 3.6 7.5 0.0 3.2 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.16 KEY65570.1 - 0.073 12.7 2.8 0.56 9.9 0.0 3.4 4 0 0 4 4 4 0 AhpC/TSA family Thioredoxin_3 PF13192.1 KEY65570.1 - 0.17 11.7 0.0 2 8.2 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_4 PF13462.1 KEY65570.1 - 1.2 9.1 6.8 5.2 7.0 0.0 3.2 3 0 0 3 3 3 0 Thioredoxin zf-FPG_IleRS PF06827.9 KEY65570.1 - 2.1 8.0 5.3 10 5.8 0.4 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Tyr-DNA_phospho PF06087.7 KEY65571.1 - 1.6e-129 432.3 0.0 1.9e-129 432.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 KEY65571.1 - 0.00094 18.9 0.0 0.94 9.2 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain MatE PF01554.13 KEY65572.1 - 4.5e-50 169.4 29.5 2.1e-27 95.7 7.2 2.2 2 0 0 2 2 2 2 MatE Zn_clus PF00172.13 KEY65574.1 - 4.9e-08 32.7 8.2 9e-08 31.9 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC27 PF09507.5 KEY65574.1 - 3.1 6.9 9.8 7.4 5.6 6.8 1.6 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DOMON PF03351.12 KEY65576.1 - 6.8e-07 29.2 2.3 3.6e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 DOMON domain DUF2427 PF10348.4 KEY65576.1 - 9.1e-05 21.9 1.1 0.00014 21.3 0.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF2427) ATP_sub_h PF10775.4 KEY65577.1 - 3.3e-24 84.3 0.3 4.4e-24 83.9 0.2 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h Paramyxo_PNT PF13825.1 KEY65577.1 - 0.034 13.3 0.0 0.036 13.2 0.0 1.0 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus Pkinase PF00069.20 KEY65578.1 - 6.2e-72 241.8 0.0 8.2e-72 241.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY65578.1 - 1.3e-31 109.5 0.0 1.9e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KEY65578.1 - 8.8e-14 51.7 0.3 5.5e-13 49.2 0.2 2.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KEY65578.1 - 8.8e-10 38.0 0.0 1.6e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C2 PF00168.25 KEY65578.1 - 1e-06 28.4 0.0 4.6e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 C2 domain Kdo PF06293.9 KEY65578.1 - 0.021 13.8 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KEY65578.1 - 0.081 12.2 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 KEY65578.1 - 0.091 12.3 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase SUZ PF12752.2 KEY65579.1 - 0.00034 21.0 4.7 0.00034 21.0 3.2 2.9 4 2 0 4 4 4 1 SUZ domain CRF PF00473.12 KEY65579.1 - 8.2 6.6 7.1 0.68 10.0 0.1 2.5 2 0 0 2 2 2 0 Corticotropin-releasing factor family Fe_hyd_lg_C PF02906.9 KEY65580.1 - 1.5e-60 204.8 0.0 3.8e-60 203.5 0.0 1.6 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain LRR19-TM PF15176.1 KEY65581.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF4395 PF14340.1 KEY65581.1 - 0.67 10.0 4.2 0.17 11.9 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4395) Neurensin PF14927.1 KEY65581.1 - 8.9 5.6 6.3 69 2.8 4.4 2.0 1 1 0 1 1 1 0 Neurensin DAHP_synth_1 PF00793.15 KEY65583.1 - 1.7e-94 315.4 0.0 2.5e-94 314.9 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family zf-H2C2_2 PF13465.1 KEY65583.1 - 3.3e-06 27.0 10.7 1.3e-05 25.2 0.9 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KEY65583.1 - 0.00016 21.8 0.5 0.00016 21.8 0.4 3.4 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY65583.1 - 0.00062 19.9 0.4 0.00062 19.9 0.3 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KEY65583.1 - 0.048 13.8 0.5 2 8.6 0.0 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Fungal_trans_2 PF11951.3 KEY65584.1 - 7.3e-39 133.4 0.4 3.6e-38 131.1 0.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF4632 PF15451.1 KEY65584.1 - 0.038 13.9 1.2 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) Pro_isomerase PF00160.16 KEY65585.1 - 8.1e-50 169.0 0.1 2e-49 167.7 0.1 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 KEY65585.1 - 1e-14 53.7 0.4 8.1e-08 31.8 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Far-17a_AIG1 PF04750.9 KEY65586.1 - 1.6e-56 190.6 13.6 1.8e-56 190.4 9.4 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein E1-E2_ATPase PF00122.15 KEY65586.1 - 0.53 9.2 1.9 2.1 7.3 1.3 1.9 1 1 0 1 1 1 0 E1-E2 ATPase Sld5 PF05916.6 KEY65587.1 - 1.3e-07 31.9 0.2 2.1e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 GINS complex protein DUF896 PF05979.7 KEY65587.1 - 0.073 12.6 0.1 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) DUF2045 PF09741.4 KEY65588.1 - 0.12 11.4 0.0 0.34 9.9 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2045) WD40 PF00400.27 KEY65589.1 - 8.6e-10 38.1 0.1 0.031 14.1 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Indigoidine_A PF04227.7 KEY65590.1 - 6.7e-103 343.9 1.6 1.1e-102 343.1 1.1 1.4 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 KEY65590.1 - 1.5e-24 86.6 0.0 5.5e-23 81.5 0.0 2.9 2 1 0 2 2 2 1 pfkB family carbohydrate kinase HTH_DeoR PF08220.7 KEY65590.1 - 0.059 12.9 1.0 0.93 9.0 0.3 2.9 2 1 0 2 2 2 0 DeoR-like helix-turn-helix domain adh_short PF00106.20 KEY65592.1 - 2.1e-23 83.0 1.3 5.5e-23 81.7 0.9 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY65592.1 - 3.1e-13 50.0 0.0 4.3e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY65592.1 - 4.1e-08 33.0 1.6 6.7e-07 29.1 0.9 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY65592.1 - 0.00015 21.2 0.1 0.00031 20.2 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY65592.1 - 0.0007 19.6 0.1 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KEY65592.1 - 0.014 14.3 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 KEY65592.1 - 0.018 13.7 0.0 0.053 12.2 0.0 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family AlaDh_PNT_C PF01262.16 KEY65592.1 - 0.063 12.8 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 KEY65593.1 - 9.8e-73 245.2 0.0 1.2e-72 244.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KEY65593.1 - 2.4e-35 121.6 0.0 4e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.9 KEY65593.1 - 3e-05 24.0 0.0 0.00022 21.1 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY65593.1 - 0.00014 21.8 0.1 0.00035 20.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KEY65593.1 - 0.00015 20.4 0.1 0.00023 19.7 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KEY65593.1 - 0.00056 20.2 0.0 0.0015 18.8 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY65593.1 - 0.00085 19.4 0.3 0.002 18.2 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY65593.1 - 0.004 16.1 0.1 0.0064 15.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 KEY65593.1 - 0.0088 14.7 0.0 0.015 13.9 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase XdhC_C PF13478.1 KEY65593.1 - 0.0096 16.2 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 1 XdhC Rossmann domain Thi4 PF01946.12 KEY65593.1 - 0.014 14.4 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 KEY65593.1 - 0.02 13.8 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEY65593.1 - 0.032 13.0 0.1 0.072 11.9 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 KEY65593.1 - 0.035 12.9 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 KEY65593.1 - 0.047 13.3 0.0 0.097 12.3 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KEY65593.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 KEY65593.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 ThiF family NAD_binding_9 PF13454.1 KEY65593.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding F-box PF00646.28 KEY65594.1 - 6.7e-05 22.4 1.1 0.00013 21.5 0.8 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KEY65594.1 - 0.066 12.9 0.2 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 F-box-like SR-25 PF10500.4 KEY65594.1 - 1.3 8.4 7.8 2.7 7.4 5.4 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1682 PF07946.9 KEY65595.1 - 9.1 5.0 7.5 12 4.6 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) AAR2 PF05282.6 KEY65596.1 - 3e-47 161.2 0.0 4.2e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein Ribosomal_S9 PF00380.14 KEY65597.1 - 6.9e-40 136.0 0.2 7.8e-40 135.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 KEY65597.1 - 0.0066 13.9 0.0 0.0076 13.7 0.0 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein Ribosomal_L32e PF01655.13 KEY65598.1 - 1.3e-49 166.8 1.2 1.6e-49 166.5 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 CBFB_NFYA PF02045.10 KEY65598.1 - 3.8 8.1 6.4 2.9 8.5 3.0 2.0 2 1 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B SH3_1 PF00018.23 KEY65599.1 - 5.7e-05 22.4 0.0 0.00011 21.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KEY65599.1 - 0.0097 15.4 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain ELFV_dehydrog PF00208.16 KEY65600.1 - 2.2e-57 194.4 0.0 3.8e-57 193.6 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 KEY65600.1 - 2.5e-20 71.6 0.0 3.4e-15 54.6 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 KEY65600.1 - 0.0005 19.6 0.0 0.0016 17.9 0.0 1.8 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Tom22 PF04281.8 KEY65602.1 - 2.3e-43 147.0 0.0 3.1e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF4581 PF15167.1 KEY65602.1 - 0.2 11.5 1.0 0.32 10.8 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) Dynamin_N PF00350.18 KEY65603.1 - 1.9e-18 66.8 0.1 1.9e-18 66.8 0.0 1.8 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 KEY65603.1 - 3.1e-10 40.0 0.2 1.5e-09 37.7 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEY65603.1 - 1e-06 28.3 0.3 7.4e-06 25.5 0.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 KEY65603.1 - 0.0083 16.4 0.0 0.026 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KEY65603.1 - 0.042 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 KEY65603.1 - 0.043 14.3 0.1 0.69 10.4 0.1 2.6 1 1 0 1 1 1 0 Miro-like protein Snf7 PF03357.16 KEY65604.1 - 2.2e-35 121.5 20.0 3.4e-35 120.9 13.9 1.3 1 0 0 1 1 1 1 Snf7 V_ATPase_I PF01496.14 KEY65604.1 - 0.0055 14.6 2.3 0.0066 14.3 1.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CaMBD PF02888.11 KEY65604.1 - 0.014 15.1 2.7 0.014 15.1 1.9 2.2 1 1 1 2 2 2 0 Calmodulin binding domain Ist1 PF03398.9 KEY65604.1 - 0.22 10.9 6.9 0.39 10.1 4.8 1.3 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway PspA_IM30 PF04012.7 KEY65604.1 - 1.1 8.5 16.1 2.1 7.6 4.0 2.2 1 1 1 2 2 2 0 PspA/IM30 family PP2C PF00481.16 KEY65605.1 - 5.3e-60 202.9 0.2 8.1e-49 166.3 0.2 3.1 2 1 0 2 2 2 2 Protein phosphatase 2C DUF4051 PF13260.1 KEY65605.1 - 0.19 11.0 0.1 2.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) Zn_clus PF00172.13 KEY65607.1 - 2.9e-07 30.2 11.9 4.5e-07 29.6 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YEATS PF03366.11 KEY65608.1 - 2.6e-19 68.7 0.0 5.4e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 YEATS family Ran_BP1 PF00638.13 KEY65609.1 - 2e-45 153.7 0.2 2e-45 153.7 0.1 1.5 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.18 KEY65609.1 - 0.014 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 WH1 domain FolB PF02152.13 KEY65612.1 - 7.6e-15 55.0 0.0 1.7e-13 50.7 0.0 2.4 2 0 0 2 2 2 1 Dihydroneopterin aldolase DUF3605 PF12239.3 KEY65613.1 - 3.1e-57 192.8 0.1 3.8e-57 192.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) UDPGP PF01704.13 KEY65614.1 - 3.7e-184 612.0 0.2 4.4e-184 611.8 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 KEY65614.1 - 0.055 12.0 3.0 0.18 10.2 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4301) DUF3244 PF11589.3 KEY65616.1 - 0.0072 16.0 2.3 0.11 12.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3244) Rifin_STEVOR PF02009.11 KEY65616.1 - 0.064 12.8 1.7 0.073 12.7 1.2 1.1 1 0 0 1 1 1 0 Rifin/stevor family DHHW PF14286.1 KEY65616.1 - 0.098 11.9 3.5 0.12 11.6 2.4 1.1 1 0 0 1 1 1 0 DHHW protein Herpes_TAF50 PF03326.8 KEY65616.1 - 0.48 9.3 10.9 0.6 9.0 7.5 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF3336 PF11815.3 KEY65618.1 - 7.9e-36 122.7 0.1 2.2e-35 121.3 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KEY65618.1 - 7.7e-14 52.0 0.2 1.7e-13 50.9 0.2 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Leo1 PF04004.8 KEY65619.1 - 5.5e-27 94.5 0.0 5.5e-27 94.5 0.0 2.0 2 0 0 2 2 2 1 Leo1-like protein TFIIF_beta PF02270.10 KEY65619.1 - 0.013 15.2 0.2 0.013 15.2 0.1 1.7 2 0 0 2 2 2 0 Transcription initiation factor IIF, beta subunit Mob1_phocein PF03637.12 KEY65620.1 - 1.1e-37 129.3 1.7 1.3e-19 70.5 0.0 2.1 2 0 0 2 2 2 2 Mob1/phocein family Fungal_trans PF04082.13 KEY65621.1 - 8.5e-13 47.7 0.0 1.4e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY65621.1 - 1e-06 28.5 9.3 2e-06 27.5 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thioredoxin_4 PF13462.1 KEY65623.1 - 6.7e-09 35.9 0.0 1.1e-08 35.1 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 KEY65623.1 - 0.0061 16.1 2.2 0.33 10.4 0.0 2.8 1 1 1 2 2 2 2 DSBA-like thioredoxin domain p450 PF00067.17 KEY65624.1 - 4.9e-13 48.4 0.0 6.8e-12 44.6 0.0 2.1 2 0 0 2 2 2 1 Cytochrome P450 PRTase_3 PF15610.1 KEY65624.1 - 0.055 12.3 0.0 0.091 11.6 0.0 1.2 1 0 0 1 1 1 0 PRTase ComF-like Zip PF02535.17 KEY65625.1 - 4.4e-48 163.9 3.6 6.4e-48 163.3 2.5 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter TRAPPC-Trs85 PF12739.2 KEY65625.1 - 0.047 12.3 0.6 0.079 11.5 0.0 1.6 2 0 0 2 2 2 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit 2OG-FeII_Oxy PF03171.15 KEY65626.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily FRG1 PF06229.7 KEY65627.1 - 2.8e-50 170.4 0.2 2.8e-50 170.4 0.1 1.8 2 0 0 2 2 2 1 FRG1-like family Fascin PF06268.8 KEY65627.1 - 0.034 14.2 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Fascin domain Frataxin_Cyay PF01491.11 KEY65627.1 - 0.045 13.5 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Frataxin-like domain WD40 PF00400.27 KEY65628.1 - 2.5e-15 55.6 2.0 0.00025 20.7 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Mito_carr PF00153.22 KEY65629.1 - 2.2e-64 213.1 2.0 7.1e-22 76.9 0.0 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein F-box-like PF12937.2 KEY65630.1 - 6.6e-11 41.7 0.0 1.3e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEY65630.1 - 0.0045 16.6 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 F-box domain TPR_11 PF13414.1 KEY65630.1 - 0.022 14.4 0.1 0.049 13.2 0.1 1.6 1 0 0 1 1 1 0 TPR repeat HemY_N PF07219.8 KEY65632.1 - 0.33 10.5 0.0 0.33 10.5 0.0 2.3 3 0 0 3 3 3 0 HemY protein N-terminus UL2 PF08196.6 KEY65632.1 - 0.34 10.6 13.7 3.9 7.2 0.6 2.8 2 0 0 2 2 2 0 UL2 protein MBOAT PF03062.14 KEY65633.1 - 5.5e-41 140.7 22.8 5.5e-41 140.7 15.8 1.7 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family ATP-grasp_4 PF13535.1 KEY65634.1 - 3.8e-12 46.3 0.0 6.2e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KEY65634.1 - 7.5e-09 34.7 0.0 2.5e-08 33.0 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Glyco_transf_4 PF13439.1 KEY65634.1 - 0.00013 21.7 0.1 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 KEY65634.1 - 0.00089 19.4 0.2 0.0025 17.9 0.2 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Epimerase PF01370.16 KEY65635.1 - 3.9e-11 42.8 0.0 1.1e-10 41.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY65635.1 - 1.4e-09 38.2 0.3 7.2e-09 35.9 0.2 2.2 1 1 0 1 1 1 1 NADH(P)-binding Zn_clus PF00172.13 KEY65635.1 - 3.4e-06 26.8 11.6 8.1e-06 25.6 8.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 3Beta_HSD PF01073.14 KEY65635.1 - 0.0029 16.3 0.0 0.0042 15.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KEY65635.1 - 0.63 9.9 0.0 0.63 9.9 0.0 2.1 3 0 0 3 3 3 0 short chain dehydrogenase Vps5 PF09325.5 KEY65636.1 - 0.002 17.4 5.0 0.0032 16.7 3.4 1.2 1 0 0 1 1 1 1 Vps5 C terminal like DUF4201 PF13870.1 KEY65636.1 - 0.011 15.1 3.3 0.021 14.2 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Sipho_Gp157 PF05565.6 KEY65636.1 - 0.019 14.5 0.5 0.032 13.8 0.4 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 DUF4164 PF13747.1 KEY65636.1 - 0.049 13.7 3.6 0.097 12.8 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) HSP70 PF00012.15 KEY65636.1 - 0.39 8.5 1.9 0.48 8.2 1.3 1.1 1 0 0 1 1 1 0 Hsp70 protein GrpE PF01025.14 KEY65636.1 - 0.4 10.1 6.1 0.71 9.3 4.2 1.3 1 0 0 1 1 1 0 GrpE Ndc1_Nup PF09531.5 KEY65636.1 - 2.3 6.5 6.2 3 6.1 4.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mnd1 PF03962.10 KEY65636.1 - 4.8 6.8 8.2 0.58 9.8 2.3 1.8 2 0 0 2 2 2 0 Mnd1 family IncA PF04156.9 KEY65636.1 - 8.6 5.9 13.4 19 4.7 9.3 1.6 1 1 0 1 1 1 0 IncA protein 2OG-FeII_Oxy_3 PF13640.1 KEY65639.1 - 0.016 15.7 0.1 0.046 14.2 0.0 1.8 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily NS3_envE PF02723.9 KEY65639.1 - 0.34 10.8 0.1 0.65 9.9 0.1 1.3 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E EIF4E-T PF10477.4 KEY65640.1 - 0.03 13.1 0.1 0.039 12.7 0.0 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E 5_nucleotid_C PF02872.13 KEY65641.1 - 2.1e-34 118.7 0.0 3.4e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KEY65641.1 - 6.7e-08 32.1 0.1 9.9e-08 31.6 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MFS_1 PF07690.11 KEY65642.1 - 3.1e-23 82.0 47.9 7.2e-19 67.6 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY65642.1 - 2.6e-16 59.2 14.8 4e-16 58.6 9.9 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Glycos_transf_1 PF00534.15 KEY65644.1 - 2.8e-37 127.7 0.0 4.3e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KEY65644.1 - 1.8e-16 60.5 0.0 3.8e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KEY65644.1 - 9.6e-16 58.3 0.1 1.6e-15 57.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KEY65644.1 - 2.7e-11 43.5 0.0 6.8e-11 42.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KEY65644.1 - 1.4e-06 28.1 0.1 4.9e-06 26.3 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 DUF485 PF04341.7 KEY65644.1 - 0.11 12.2 0.7 0.24 11.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF485 UDPG_MGDP_dh_N PF03721.9 KEY65645.1 - 8.4e-48 162.2 0.0 1.9e-30 105.5 0.0 2.3 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 KEY65645.1 - 5.5e-32 109.8 0.0 1.2e-31 108.7 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 KEY65645.1 - 3.4e-24 85.0 0.0 1.7e-17 63.4 0.0 3.4 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_Gly3P_dh_N PF01210.18 KEY65645.1 - 0.0019 17.9 0.2 0.14 11.8 0.0 3.2 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 KEY65645.1 - 0.029 13.3 0.0 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 KEY65645.1 - 0.048 13.5 0.0 1.2 8.9 0.0 2.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PA14_2 PF10528.4 KEY65647.1 - 1.4e-13 50.7 0.0 3.1e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 GLEYA domain FG-GAP PF01839.18 KEY65647.1 - 0.083 12.6 19.5 0.015 15.0 2.6 3.4 1 1 2 3 3 3 0 FG-GAP repeat VanY PF02557.12 KEY65648.1 - 0.0029 17.4 0.1 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase DUF3636 PF12331.3 KEY65649.1 - 3.4e-22 78.6 0.2 7.8e-22 77.4 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) DUF2046 PF09755.4 KEY65649.1 - 0.0038 16.1 2.4 0.0073 15.2 1.6 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) DUF1664 PF07889.7 KEY65649.1 - 0.12 12.2 0.4 0.28 10.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.3 KEY65649.1 - 6 6.6 11.1 0.78 9.4 4.4 2.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3128 PF11326.3 KEY65650.1 - 5.8e-28 96.8 2.6 1.1e-27 95.9 1.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) RNA12 PF10443.4 KEY65651.1 - 2.6e-157 523.7 0.8 3.5e-157 523.3 0.0 1.6 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.17 KEY65651.1 - 9.8e-05 21.9 0.0 0.0003 20.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 KEY65651.1 - 0.00012 21.8 0.0 0.0018 18.0 0.0 2.4 1 1 0 1 1 1 1 Archaeal ATPase DUF4468 PF14730.1 KEY65651.1 - 0.008 15.8 0.0 4 7.1 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4468) with TBP-like fold AAA_16 PF13191.1 KEY65651.1 - 0.015 15.3 0.1 0.16 11.9 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain RRM_5 PF13893.1 KEY65651.1 - 0.021 14.6 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_19 PF13245.1 KEY65651.1 - 0.048 13.4 0.0 16 5.3 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain CENP-C_C PF11699.3 KEY65652.1 - 3.7e-33 113.3 0.1 5.8e-33 112.7 0.1 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 KEY65652.1 - 4.8e-07 29.1 0.0 1.4e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 KEY65652.1 - 0.061 12.7 0.1 0.34 10.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Cupin_6 PF12852.2 KEY65652.1 - 0.094 12.3 0.0 0.32 10.5 0.0 1.8 1 1 1 2 2 2 0 Cupin DDE_5 PF13546.1 KEY65652.1 - 8.7 5.1 9.2 4.4 6.0 1.5 2.4 3 0 0 3 3 3 0 DDE superfamily endonuclease DMRL_synthase PF00885.14 KEY65654.1 - 1.1e-46 158.0 0.6 1.6e-44 151.0 0.4 2.0 1 1 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase HATPase_c_3 PF13589.1 KEY65655.1 - 3e-12 46.3 0.0 5.9e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 KEY65655.1 - 4.6e-10 39.0 0.0 1.7e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 KEY65655.1 - 5.1e-08 32.6 0.1 1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TRP PF06011.7 KEY65656.1 - 9.2e-85 284.8 29.2 3.5e-83 279.6 20.3 2.0 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KEY65656.1 - 8.4e-22 77.7 0.0 1.2e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 ML-like domain RNase_T PF00929.19 KEY65657.1 - 4.5e-24 85.5 0.0 6.7e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease IncA PF04156.9 KEY65658.1 - 0.0002 21.0 5.3 0.00029 20.5 3.6 1.3 1 0 0 1 1 1 1 IncA protein ERM PF00769.14 KEY65658.1 - 0.00026 20.5 6.8 0.00036 20.1 4.7 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Herpes_BLRF2 PF05812.7 KEY65658.1 - 0.0023 17.7 0.8 0.0046 16.7 0.6 1.5 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein HOOK PF05622.7 KEY65658.1 - 0.0089 13.8 2.8 0.011 13.6 1.9 1.1 1 0 0 1 1 1 1 HOOK protein APG6 PF04111.7 KEY65658.1 - 0.01 14.9 4.3 0.015 14.3 2.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 KEY65658.1 - 0.011 14.2 1.1 0.013 13.9 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 KEY65658.1 - 0.011 16.0 4.5 0.043 14.1 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Spc7 PF08317.6 KEY65658.1 - 0.011 14.3 3.7 0.016 13.8 2.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.10 KEY65658.1 - 0.022 14.2 5.3 0.084 12.3 1.9 2.6 1 1 2 3 3 3 0 Septum formation initiator WEMBL PF05701.6 KEY65658.1 - 0.027 12.9 7.7 0.053 11.9 5.4 1.5 1 1 0 1 1 1 0 Weak chloroplast movement under blue light ADIP PF11559.3 KEY65658.1 - 0.032 14.1 6.2 0.076 12.9 4.2 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.10 KEY65658.1 - 0.034 13.9 3.5 0.055 13.2 1.1 2.2 2 0 0 2 2 2 0 Basic region leucine zipper DUF3450 PF11932.3 KEY65658.1 - 0.037 13.3 0.8 0.052 12.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CCDC92 PF14916.1 KEY65658.1 - 0.037 13.6 0.3 0.1 12.2 0.2 1.8 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Mod_r PF07200.8 KEY65658.1 - 0.038 13.9 3.7 0.095 12.6 2.1 1.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Ax_dynein_light PF10211.4 KEY65658.1 - 0.04 13.7 4.5 0.069 12.9 2.7 1.6 1 1 0 1 1 1 0 Axonemal dynein light chain Phage_GP20 PF06810.6 KEY65658.1 - 0.045 13.1 2.2 0.093 12.1 1.5 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF4019 PF13211.1 KEY65658.1 - 0.047 13.9 1.5 0.17 12.1 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4019) Reo_sigmaC PF04582.7 KEY65658.1 - 0.067 12.3 1.4 0.4 9.8 0.2 2.0 1 1 0 2 2 2 0 Reovirus sigma C capsid protein HALZ PF02183.13 KEY65658.1 - 0.077 12.7 0.6 0.077 12.7 0.4 3.1 4 0 0 4 4 3 0 Homeobox associated leucine zipper COG5 PF10392.4 KEY65658.1 - 0.078 12.9 1.2 0.2 11.5 0.8 1.8 1 1 0 1 1 1 0 Golgi transport complex subunit 5 EzrA PF06160.7 KEY65658.1 - 0.08 11.1 4.2 0.12 10.5 2.9 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TMF_DNA_bd PF12329.3 KEY65658.1 - 0.09 12.5 10.8 0.56 10.0 6.8 2.6 2 1 1 3 3 2 0 TATA element modulatory factor 1 DNA binding Snapin_Pallidin PF14712.1 KEY65658.1 - 0.11 12.7 2.2 0.39 11.0 1.5 2.0 1 1 0 1 1 1 0 Snapin/Pallidin DUF641 PF04859.7 KEY65658.1 - 0.12 12.1 1.4 0.16 11.7 0.3 1.9 2 0 0 2 2 1 0 Plant protein of unknown function (DUF641) AAA_13 PF13166.1 KEY65658.1 - 0.12 10.7 3.9 0.15 10.4 2.7 1.1 1 0 0 1 1 1 0 AAA domain K-box PF01486.12 KEY65658.1 - 0.15 11.8 3.7 0.27 11.0 1.4 2.2 1 1 1 2 2 2 0 K-box region Nnf1 PF03980.9 KEY65658.1 - 0.15 12.0 5.3 0.2 11.6 2.5 2.3 2 1 0 2 2 1 0 Nnf1 DUF724 PF05266.9 KEY65658.1 - 0.18 11.3 7.0 0.15 11.6 3.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) VASP_tetra PF08776.6 KEY65658.1 - 0.2 11.0 4.5 1.3 8.4 0.1 3.3 3 1 0 3 3 3 0 VASP tetramerisation domain Tropomyosin PF00261.15 KEY65658.1 - 0.21 10.6 10.5 0.32 10.0 7.3 1.2 1 0 0 1 1 1 0 Tropomyosin TMF_TATA_bd PF12325.3 KEY65658.1 - 0.26 11.0 8.7 2 8.1 6.2 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc24 PF08286.6 KEY65658.1 - 0.26 10.9 6.1 0.72 9.5 3.6 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 MscS_porin PF12795.2 KEY65658.1 - 0.3 10.3 6.9 0.45 9.7 3.7 1.8 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain TBPIP PF07106.8 KEY65658.1 - 0.49 9.9 5.3 0.87 9.1 3.0 1.7 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4200 PF13863.1 KEY65658.1 - 0.5 10.3 8.8 0.37 10.7 3.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Mnd1 PF03962.10 KEY65658.1 - 0.53 9.9 7.4 1.1 8.8 4.7 1.7 1 1 0 1 1 1 0 Mnd1 family TPR_MLP1_2 PF07926.7 KEY65658.1 - 0.62 9.8 7.9 2.6 7.7 4.4 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spectrin PF00435.16 KEY65658.1 - 0.66 10.2 5.5 0.56 10.5 2.7 1.6 2 0 0 2 2 1 0 Spectrin repeat Med9 PF07544.8 KEY65658.1 - 0.66 9.7 5.5 21 4.9 2.6 2.7 2 1 1 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 bZIP_1 PF00170.16 KEY65658.1 - 1 9.3 8.2 0.39 10.7 1.6 2.6 2 1 0 2 2 2 0 bZIP transcription factor DUF4164 PF13747.1 KEY65658.1 - 1.2 9.2 7.2 0.56 10.3 2.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF904 PF06005.7 KEY65658.1 - 2.2 8.6 9.2 6.9 7.0 5.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF904) V_ATPase_I PF01496.14 KEY65658.1 - 2.5 5.8 5.8 4.8 4.8 3.6 1.4 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF1192 PF06698.6 KEY65658.1 - 3.8 7.3 5.5 14 5.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Cep57_CLD_2 PF14197.1 KEY65658.1 - 4.6 7.2 8.9 13 5.7 4.3 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 SET PF00856.23 KEY65659.1 - 1.6e-09 38.2 0.0 1.6e-08 35.0 0.0 2.3 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 KEY65659.1 - 2.4e-08 33.6 11.6 4.4e-08 32.8 8.0 1.4 1 0 0 1 1 1 1 MYND finger TSCPD PF12637.2 KEY65660.1 - 0.056 13.3 0.0 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 TSCPD domain Glutaredoxin PF00462.19 KEY65661.1 - 2.2e-13 49.9 1.7 2.7e-13 49.7 0.0 2.0 3 0 0 3 3 3 1 Glutaredoxin EF-1_beta_acid PF10587.4 KEY65661.1 - 3.7 7.7 8.2 0.4 10.8 0.5 2.4 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Zn_clus PF00172.13 KEY65662.1 - 9.6e-08 31.8 12.0 1.6e-07 31.1 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SR-25 PF10500.4 KEY65662.1 - 1.3 8.4 15.1 2.1 7.7 10.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HLH PF00010.21 KEY65663.1 - 6e-13 48.2 1.3 1.7e-12 46.8 0.9 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HALZ PF02183.13 KEY65663.1 - 0.077 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.10 KEY65663.1 - 0.11 11.9 0.5 0.24 10.9 0.3 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF972 PF06156.8 KEY65663.1 - 0.18 12.1 0.2 0.47 10.8 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) TPR_1 PF00515.23 KEY65666.1 - 1.2e-26 91.1 2.1 1.6e-07 30.6 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 KEY65666.1 - 5.1e-26 90.1 9.4 3.3e-10 39.4 0.5 4.4 3 1 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 KEY65666.1 - 1.1e-24 84.3 4.2 4.7e-07 29.2 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 KEY65666.1 - 1.1e-18 66.0 6.3 1.5e-05 25.2 0.1 6.0 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEY65666.1 - 4.5e-18 65.4 6.9 3.9e-06 27.3 1.9 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEY65666.1 - 8.1e-16 56.8 6.7 0.0048 16.9 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 KEY65666.1 - 7.8e-15 53.4 2.5 0.0011 18.6 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEY65666.1 - 4e-13 48.1 2.8 0.00011 21.7 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEY65666.1 - 4.6e-12 46.1 13.5 0.0012 19.1 3.8 5.5 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 KEY65666.1 - 1.5e-10 40.8 13.1 1.7e-07 31.0 0.4 4.4 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 KEY65666.1 - 8.5e-10 38.4 1.6 0.33 11.5 0.1 6.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 KEY65666.1 - 1.2e-09 38.1 3.4 0.0038 17.3 0.1 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 KEY65666.1 - 2e-08 33.9 2.2 0.0087 15.8 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KEY65666.1 - 4.1e-05 23.6 4.4 0.079 13.1 0.3 2.8 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KEY65666.1 - 0.00018 20.6 6.8 0.25 10.3 0.3 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.7 KEY65666.1 - 0.0039 16.9 1.3 7.2 6.5 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat MIT PF04212.13 KEY65666.1 - 0.012 15.5 1.3 16 5.4 0.0 4.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain NatB_MDM20 PF09797.4 KEY65666.1 - 0.016 13.9 0.0 0.032 12.9 0.0 1.5 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit DED PF01335.16 KEY65666.1 - 0.018 15.1 0.3 7.6 6.7 0.0 2.7 3 0 0 3 3 2 0 Death effector domain Death PF00531.17 KEY65666.1 - 0.026 14.2 0.2 1.7 8.4 0.0 3.5 3 0 0 3 3 3 0 Death domain TPR_10 PF13374.1 KEY65666.1 - 0.028 14.3 4.6 0.5 10.3 0.3 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TOM20_plant PF06552.7 KEY65666.1 - 0.054 13.0 0.6 2.1 7.8 0.0 3.6 2 2 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 Brix PF04427.13 KEY65667.1 - 3.4e-36 124.7 0.3 4.3e-36 124.3 0.2 1.1 1 0 0 1 1 1 1 Brix domain Zn_clus PF00172.13 KEY65668.1 - 5.3e-08 32.6 10.4 8.4e-08 31.9 7.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEY65668.1 - 0.00049 18.8 0.0 0.00069 18.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cys_Met_Meta_PP PF01053.15 KEY65669.1 - 1.3e-136 454.9 0.1 1.5e-136 454.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KEY65669.1 - 5e-07 28.7 0.3 1.1e-06 27.6 0.1 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KEY65669.1 - 1.2e-05 24.4 0.1 1.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KEY65669.1 - 6.1e-05 22.2 0.3 0.0001 21.4 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.11 KEY65669.1 - 0.0034 16.1 0.1 0.0051 15.5 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein 2-Hacid_dh PF00389.25 KEY65669.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F-box-like PF12937.2 KEY65670.1 - 0.058 13.1 0.2 0.56 9.9 0.0 2.5 2 0 0 2 2 2 0 F-box-like Pex14_N PF04695.8 KEY65671.1 - 0.21 11.6 2.9 0.11 12.5 0.4 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hamartin PF04388.7 KEY65671.1 - 5.2 5.6 11.1 6.2 5.3 7.7 1.1 1 0 0 1 1 1 0 Hamartin protein Amidoligase_2 PF12224.3 KEY65672.1 - 4.6e-21 75.5 0.0 6.6e-20 71.7 0.0 2.2 2 0 0 2 2 2 1 Putative amidoligase enzyme RNA_pol_Rpb1_5 PF04998.12 KEY65673.1 - 2.8e-86 289.2 0.0 7.5e-86 287.8 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 KEY65673.1 - 9.7e-80 268.3 0.0 1.4e-79 267.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 KEY65673.1 - 4.8e-64 215.3 0.0 9.2e-64 214.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KEY65673.1 - 2.6e-39 134.4 0.0 5.2e-39 133.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KEY65673.1 - 4e-30 103.7 0.1 1.1e-29 102.2 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 DUF2296 PF10058.4 KEY65673.1 - 0.083 12.6 0.3 0.58 9.9 0.1 2.5 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) PC_rep PF01851.17 KEY65674.1 - 1.5e-42 141.4 16.3 5.1e-08 32.7 0.0 9.4 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KEY65674.1 - 1.4e-18 66.9 0.1 5.3e-12 45.8 0.0 4.9 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.17 KEY65674.1 - 1.6e-08 33.9 0.1 2.3 8.5 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 KEY65674.1 - 1.4e-06 28.5 3.7 0.00091 19.6 0.0 5.4 6 1 1 7 7 7 1 HEAT-like repeat Oxidored_molyb PF00174.14 KEY65675.1 - 5.4e-53 178.8 0.0 7.8e-53 178.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KEY65675.1 - 1.9e-32 111.6 0.4 3.3e-32 110.8 0.3 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 KEY65675.1 - 4.5e-13 48.8 0.2 8.2e-13 47.9 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CTP_transf_2 PF01467.21 KEY65678.1 - 1.8e-05 24.8 0.0 0.00012 22.2 0.0 2.1 2 0 0 2 2 2 1 Cytidylyltransferase DUF3506 PF12014.3 KEY65679.1 - 9.1e-47 158.2 0.0 2.2e-46 156.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 KEY65679.1 - 2.5e-05 23.8 0.2 4.8e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEY65679.1 - 0.0039 16.8 0.0 0.0067 16.0 0.0 1.4 1 0 0 1 1 1 1 F-box domain Cupin_2 PF07883.6 KEY65680.1 - 2.8e-10 39.5 0.1 4.2e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 KEY65680.1 - 0.0011 18.2 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) ARD PF03079.9 KEY65680.1 - 0.0013 18.6 0.1 0.0018 18.2 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.2 KEY65680.1 - 0.019 14.6 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Cupin AraC_binding PF02311.14 KEY65680.1 - 0.038 13.6 0.1 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_1 PF00190.17 KEY65680.1 - 0.076 12.4 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Cupin Abhydrolase_6 PF12697.2 KEY65681.1 - 1.2e-11 44.9 1.5 1.2e-11 44.9 1.1 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY65681.1 - 0.00033 20.3 0.0 0.0029 17.2 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY65681.1 - 0.0099 15.6 0.5 0.12 12.1 0.2 2.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family zf-C3HC4_2 PF13923.1 KEY65682.1 - 0.0029 17.6 1.5 0.0029 17.6 1.0 2.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY65682.1 - 0.49 10.1 11.9 0.033 13.9 3.9 2.4 2 1 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KEY65682.1 - 2.4 7.8 15.2 0.05 13.2 5.1 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1769 PF08588.5 KEY65683.1 - 3.6e-29 100.4 0.2 7.2e-29 99.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Glycophorin_A PF01102.13 KEY65684.1 - 0.00051 19.8 1.6 0.0014 18.4 0.0 2.3 2 1 0 2 2 2 1 Glycophorin A Adeno_E3_CR2 PF02439.10 KEY65684.1 - 0.001 18.5 0.8 0.0016 17.9 0.6 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 RCR PF12273.3 KEY65684.1 - 0.0062 17.0 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Rifin_STEVOR PF02009.11 KEY65684.1 - 0.008 15.8 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 Rifin/stevor family TMEM51 PF15345.1 KEY65684.1 - 0.0092 15.6 0.4 0.021 14.5 0.2 1.5 1 1 0 1 1 1 1 Transmembrane protein 51 DUF1180 PF06679.7 KEY65684.1 - 0.012 15.5 0.8 0.012 15.5 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Syndecan PF01034.15 KEY65684.1 - 0.014 15.0 1.2 0.023 14.3 0.8 1.3 1 0 0 1 1 1 0 Syndecan domain Herpes_gE PF02480.11 KEY65684.1 - 0.017 13.4 0.0 0.023 12.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Romo1 PF10247.4 KEY65684.1 - 0.043 14.0 0.0 0.092 12.9 0.0 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 TMEM154 PF15102.1 KEY65684.1 - 0.045 13.4 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family Mid2 PF04478.7 KEY65684.1 - 0.055 12.8 0.4 0.099 12.0 0.3 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.1 KEY65684.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain H_PPase PF03030.11 KEY65684.1 - 0.19 9.9 0.1 0.26 9.4 0.0 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase SKG6 PF08693.5 KEY65684.1 - 0.93 8.8 9.1 1.7 8.0 6.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Lamp PF01299.12 KEY65684.1 - 3.4 6.7 11.9 0.052 12.6 2.6 2.0 1 1 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) MFS_1 PF07690.11 KEY65685.1 - 5.4e-28 97.7 29.1 5.4e-28 97.7 20.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF204 PF02659.10 KEY65685.1 - 0.68 10.0 14.2 0.35 11.0 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function DUF Polysacc_synt_4 PF04669.8 KEY65686.1 - 1.5e-25 89.7 1.4 7.7e-25 87.3 1.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis Sod_Fe_C PF02777.13 KEY65686.1 - 0.056 13.2 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, C-terminal domain ABC_tran PF00005.22 KEY65687.1 - 3.3e-61 205.5 0.0 2.6e-30 105.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEY65687.1 - 4.3e-61 206.7 15.4 1.4e-30 106.6 0.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KEY65687.1 - 1.5e-14 53.7 0.0 9.7e-06 24.9 0.0 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEY65687.1 - 2.8e-14 53.7 0.0 0.027 14.4 0.0 4.2 3 1 0 4 4 4 4 AAA domain AAA_29 PF13555.1 KEY65687.1 - 2.9e-09 36.3 1.7 0.0017 17.8 0.7 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KEY65687.1 - 3.4e-08 32.8 0.0 0.0031 16.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEY65687.1 - 5.6e-07 29.7 0.0 0.014 15.5 0.0 3.5 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KEY65687.1 - 7.1e-07 28.1 0.9 0.00011 20.9 0.0 3.7 4 1 0 4 4 4 1 Predicted ATPase of the ABC class AAA_16 PF13191.1 KEY65687.1 - 2.7e-06 27.4 6.0 0.00023 21.2 0.1 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 KEY65687.1 - 1.2e-05 24.9 1.0 0.34 10.2 0.0 3.6 4 0 0 4 4 4 2 AAA-like domain AAA_25 PF13481.1 KEY65687.1 - 1.7e-05 24.3 0.5 0.78 9.0 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KEY65687.1 - 0.00013 22.7 0.0 0.29 11.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KEY65687.1 - 0.0004 20.7 0.3 1.2 9.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KEY65687.1 - 0.00074 19.4 0.2 0.64 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KEY65687.1 - 0.00097 18.8 0.3 1.2 8.7 0.0 3.2 3 0 0 3 3 3 1 NACHT domain ATP-synt_ab PF00006.20 KEY65687.1 - 0.0016 17.9 0.1 0.21 11.0 0.0 2.7 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 KEY65687.1 - 0.0016 17.8 0.1 1.7 8.0 0.0 3.5 3 0 0 3 3 3 1 IstB-like ATP binding protein MobB PF03205.9 KEY65687.1 - 0.0017 18.0 0.7 0.42 10.3 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KEY65687.1 - 0.0025 18.1 2.0 2.3 8.5 0.0 3.3 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 KEY65687.1 - 0.0055 16.4 0.0 4.3 7.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Miro PF08477.8 KEY65687.1 - 0.0076 16.7 0.0 2.1 8.8 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein RNA_helicase PF00910.17 KEY65687.1 - 0.0091 16.1 0.0 3.7 7.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.18 KEY65687.1 - 0.02 14.8 0.1 2.3 8.1 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Rad17 PF03215.10 KEY65687.1 - 0.028 13.1 0.0 0.052 12.2 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SbcCD_C PF13558.1 KEY65687.1 - 0.042 13.7 4.3 5.5 6.9 0.0 3.8 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 KEY65687.1 - 0.054 13.3 1.0 7.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_14 PF13173.1 KEY65687.1 - 0.061 13.2 0.0 1.1 9.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain T2SE PF00437.15 KEY65687.1 - 0.16 10.8 0.7 4 6.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 KEY65687.1 - 0.21 11.2 0.2 5 6.7 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 KEY65687.1 - 0.23 11.0 1.0 21 4.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KEY65687.1 - 0.28 10.2 2.8 2.8 7.0 0.1 2.7 3 0 0 3 3 3 0 KaiC AAA_13 PF13166.1 KEY65687.1 - 0.64 8.4 0.0 7.6 4.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.1 KEY65687.1 - 1.7 7.5 0.0 19 4.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain NUP PF06516.6 KEY65689.1 - 1.2e-112 375.8 0.0 1.4e-112 375.6 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Pkinase PF00069.20 KEY65690.1 - 6.5e-44 150.0 0.0 1.8e-43 148.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY65690.1 - 6.9e-31 107.2 0.0 9.7e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KEY65690.1 - 0.00066 18.8 0.0 0.0045 16.0 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KEY65690.1 - 0.0013 17.7 0.0 0.0028 16.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 KEY65690.1 - 0.068 11.9 0.2 1.5 7.5 0.0 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Zn_clus PF00172.13 KEY65693.1 - 4.9e-07 29.5 7.5 1e-06 28.5 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_61 PF03443.9 KEY65695.1 - 2e-49 168.3 0.0 2.3e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 KEY65695.1 - 0.071 13.1 0.0 0.87 9.6 0.0 2.4 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase PK PF00224.16 KEY65696.1 - 7.4e-170 564.1 4.8 1.1e-169 563.6 3.4 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KEY65696.1 - 1.7e-32 111.4 0.0 4.5e-32 110.0 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KEY65696.1 - 0.00023 20.1 1.3 0.0006 18.7 0.6 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 KEY65696.1 - 0.007 15.2 0.0 0.18 10.6 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain DUF1748 PF08520.5 KEY65698.1 - 1.4e-34 117.5 0.1 1.7e-34 117.2 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) CK2S PF15011.1 KEY65699.1 - 0.036 13.8 0.2 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Casein Kinase 2 substrate Jnk-SapK_ap_N PF09744.4 KEY65699.1 - 0.52 10.2 7.4 0.044 13.7 1.6 1.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DivIC PF04977.10 KEY65699.1 - 1.1 8.7 3.7 0.51 9.8 0.2 2.1 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 KEY65699.1 - 2.3 7.7 5.6 0.37 10.3 0.8 1.9 2 0 0 2 2 2 0 IncA protein WD40 PF00400.27 KEY65700.1 - 1.9e-22 78.2 6.9 1.7e-09 37.1 0.0 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat Cellulase-like PF12876.2 KEY65700.1 - 0.034 14.6 0.5 0.39 11.1 0.0 3.0 3 0 0 3 3 3 0 Sugar-binding cellulase-like CTD PF12815.2 KEY65701.1 - 3.3e-24 85.6 60.9 5.6e-17 62.2 9.7 4.6 1 1 3 4 4 4 3 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 KEY65701.1 - 3.6e-18 65.1 0.0 6e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 KEY65701.1 - 4e-16 59.4 8.2 4e-16 59.4 5.7 3.5 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 KEY65701.1 - 8.2e-06 25.3 20.0 0.0045 16.6 1.6 5.4 6 0 0 6 6 6 3 KOW motif DUF605 PF04652.11 KEY65702.1 - 0.12 11.7 15.5 0.15 11.4 10.8 1.1 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 KEY65702.1 - 0.53 10.1 12.8 0.65 9.8 8.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fungal_trans PF04082.13 KEY65704.1 - 1.5e-14 53.4 0.1 2.4e-14 52.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY65704.1 - 2.5e-08 33.6 10.2 5.3e-08 32.6 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FGGY_C PF02782.11 KEY65705.1 - 2.2e-71 239.5 0.9 4.3e-71 238.6 0.7 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KEY65705.1 - 1.4e-68 230.8 0.0 1.8e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.15 KEY65706.1 - 9.7e-51 172.4 11.4 1.2e-50 172.1 7.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein DAO PF01266.19 KEY65707.1 - 4.7e-49 167.1 0.1 6.3e-49 166.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEY65707.1 - 1.1e-07 31.0 1.6 0.0025 16.7 0.5 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 KEY65707.1 - 1.6e-06 27.4 1.9 5.2e-05 22.5 0.6 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEY65707.1 - 0.0015 18.4 0.1 0.004 17.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KEY65707.1 - 0.016 14.8 0.6 0.033 13.8 0.4 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 KEY65707.1 - 0.049 13.6 0.4 0.25 11.3 0.4 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KEY65707.1 - 0.069 11.6 0.4 0.11 10.9 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 KEY65707.1 - 0.075 13.4 0.2 0.19 12.1 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEY65707.1 - 0.079 11.8 0.1 0.34 9.7 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 KEY65707.1 - 0.099 11.7 0.8 0.21 10.6 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Hydrophobin_2 PF06766.6 KEY65708.1 - 2.8e-23 81.3 11.1 3.6e-23 81.0 7.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Aa_trans PF01490.13 KEY65709.1 - 8.5e-74 248.4 24.0 1.1e-73 248.1 16.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UPF0233 PF06781.7 KEY65709.1 - 9.4 5.9 7.0 5.4 6.7 0.1 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) Iso_dh PF00180.15 KEY65711.1 - 3.8e-97 325.3 0.0 5.9e-97 324.7 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase tRNA-synt_His PF13393.1 KEY65712.1 - 7.7e-45 153.2 0.0 9.9e-43 146.3 0.0 2.5 3 0 0 3 3 3 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KEY65712.1 - 1.4e-15 57.2 0.0 2.8e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KEY65712.1 - 1.3e-09 37.8 0.1 3.9e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.15 KEY65712.1 - 0.0066 15.2 0.0 1.1 7.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 KEY65712.1 - 0.015 14.4 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Aa_trans PF01490.13 KEY65713.1 - 1.5e-82 277.2 12.5 1.5e-82 277.2 8.7 1.4 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Spore_permease PF03845.8 KEY65713.1 - 0.0015 17.2 3.9 0.0015 17.2 2.7 2.5 3 0 0 3 3 3 2 Spore germination protein DNA_pol_B_exo1 PF03104.14 KEY65713.1 - 0.1 11.4 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain YfhO PF09586.5 KEY65713.1 - 1.8 6.4 8.1 0.12 10.3 2.3 1.4 2 0 0 2 2 2 0 Bacterial membrane protein YfhO Ribosomal_S16 PF00886.14 KEY65714.1 - 7.2e-25 86.4 0.0 1.1e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.10 KEY65715.1 - 7.3e-16 58.2 0.0 2.2e-14 53.4 0.0 2.0 1 1 1 2 2 2 2 YjeF-related protein N-terminus ABC_sub_bind PF04392.7 KEY65715.1 - 0.16 10.8 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 ABC transporter substrate binding protein AA_permease PF00324.16 KEY65716.1 - 6.2e-118 394.1 50.3 7.4e-118 393.9 34.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEY65716.1 - 1.4e-30 106.1 55.6 1.9e-30 105.7 38.5 1.1 1 0 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.19 KEY65717.1 - 2.6e-84 283.4 27.4 3.2e-84 283.1 19.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY65717.1 - 2.2e-09 36.4 49.0 4e-06 25.7 14.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pirin PF02678.11 KEY65718.1 - 6.8e-25 87.0 2.0 3.9e-24 84.5 1.4 2.0 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 KEY65718.1 - 4.3e-05 22.9 3.7 0.0061 16.0 0.6 3.3 2 1 0 2 2 2 2 Cupin domain Oxysterol_BP PF01237.13 KEY65720.1 - 3.5e-126 420.4 0.0 1.3e-125 418.5 0.0 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 KEY65720.1 - 2.9e-16 59.5 0.0 1.4e-10 41.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEY65720.1 - 2.6e-15 56.0 0.1 1.4e-09 37.9 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KEY65720.1 - 1.1e-14 53.4 0.0 4.7e-06 26.1 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KEY65720.1 - 1.6e-12 47.5 0.0 1.1e-06 28.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.24 KEY65720.1 - 3.5e-12 46.4 0.5 1.1e-11 44.7 0.3 2.0 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.1 KEY65720.1 - 1.7e-11 43.1 0.0 0.00096 19.1 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.1 KEY65720.1 - 8.1e-08 32.2 1.0 1.8e-07 31.0 0.7 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain 4HBT_3 PF13622.1 KEY65721.1 - 8.2e-46 156.8 6.2 1e-45 156.4 4.3 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KEY65721.1 - 2.5e-24 85.3 0.0 3.6e-12 46.0 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Opi1 PF08618.5 KEY65721.1 - 0.079 11.8 0.2 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 Asp PF00026.18 KEY65722.1 - 5.5e-61 206.5 0.0 8.4e-61 205.9 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEY65722.1 - 6.3e-09 35.9 0.0 2.3e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KEY65722.1 - 3.2e-05 24.3 1.3 0.93 10.0 0.0 3.7 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 KEY65722.1 - 0.00074 19.2 0.0 0.052 13.3 0.0 3.0 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.1 KEY65722.1 - 0.0021 17.6 0.0 0.0048 16.4 0.0 1.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal RVP PF00077.15 KEY65722.1 - 0.0064 16.3 0.2 2.8 7.9 0.0 2.7 2 0 0 2 2 2 2 Retroviral aspartyl protease RRM_6 PF14259.1 KEY65723.1 - 4e-11 42.7 0.0 5.9e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 KEY65723.1 - 1.4e-09 37.5 0.3 2.8e-09 36.5 0.2 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.17 KEY65723.1 - 2.3e-09 36.7 0.0 3.9e-05 23.1 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 KEY65723.1 - 6.4e-06 25.9 0.5 2.8e-05 23.8 0.4 2.1 1 0 0 1 1 1 1 DExH-box splicing factor binding site zf-RanBP PF00641.13 KEY65723.1 - 2.9e-05 23.0 4.7 6.3e-05 21.9 3.3 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_5 PF13893.1 KEY65723.1 - 0.021 14.6 0.0 10 6.0 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-ribbon_3 PF13248.1 KEY65723.1 - 0.03 13.5 3.8 0.055 12.6 2.6 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.2 KEY65723.1 - 0.045 13.5 3.3 0.033 13.9 0.8 1.7 2 0 0 2 2 2 0 Double zinc ribbon RED_N PF07808.8 KEY65723.1 - 0.12 11.5 8.0 0.37 9.9 5.6 1.8 1 0 0 1 1 1 0 RED-like protein N-terminal region zf-C2H2_2 PF12756.2 KEY65723.1 - 0.13 12.3 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) MoaE PF02391.12 KEY65724.1 - 3.3e-32 110.7 0.0 4.2e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 MoaE protein Ferric_reduct PF01794.14 KEY65726.1 - 4e-19 68.9 5.4 4e-19 68.9 3.7 2.6 3 1 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KEY65726.1 - 1.3e-14 53.9 0.0 2.4e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KEY65726.1 - 7e-13 48.7 0.0 1.7e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KEY65726.1 - 0.0011 19.4 0.0 0.12 12.9 0.0 2.6 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain RNase_PH PF01138.16 KEY65727.1 - 2.7e-19 69.7 0.0 5.5e-19 68.7 0.0 1.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KEY65727.1 - 0.083 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 GDI PF00996.13 KEY65728.1 - 1.2e-40 139.1 0.0 2.2e-40 138.3 0.0 1.3 1 1 0 1 1 1 1 GDP dissociation inhibitor Rad21_Rec8_N PF04825.8 KEY65729.1 - 2.7e-28 98.1 0.0 4.2e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KEY65729.1 - 7.6e-06 25.0 0.0 2e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Aminotran_1_2 PF00155.16 KEY65730.1 - 1.8e-28 99.5 0.0 2.2e-22 79.4 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II Fungal_trans PF04082.13 KEY65731.1 - 3.1e-10 39.3 0.1 7.3e-10 38.1 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY65731.1 - 0.0021 17.8 7.1 0.0048 16.7 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEAT_EZ PF13513.1 KEY65732.1 - 2.7e-13 49.9 9.3 7.9e-08 32.5 0.0 8.5 8 2 1 9 9 9 2 HEAT-like repeat HEAT_2 PF13646.1 KEY65732.1 - 6e-12 45.6 16.4 2.7e-05 24.3 0.0 7.7 2 1 4 7 7 7 4 HEAT repeats HEAT PF02985.17 KEY65732.1 - 5e-11 41.7 13.9 0.0066 16.4 0.0 9.7 12 0 0 12 12 12 3 HEAT repeat IBN_N PF03810.14 KEY65732.1 - 3e-10 39.8 8.1 5.6e-09 35.8 1.4 4.0 4 0 0 4 4 4 1 Importin-beta N-terminal domain CLASP_N PF12348.3 KEY65732.1 - 1.9e-06 27.4 1.5 0.94 8.7 0.1 5.3 1 1 4 5 5 5 3 CLASP N terminal Arm PF00514.18 KEY65732.1 - 0.037 13.8 4.4 8.3 6.4 0.0 5.2 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 KEY65732.1 - 0.063 13.7 2.9 94 3.9 0.0 5.6 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Cse1 PF08506.5 KEY65732.1 - 0.064 11.8 0.0 1.6 7.2 0.0 3.0 3 1 0 3 3 3 0 Cse1 Zip PF02535.17 KEY65733.1 - 8.5 5.2 6.7 2.4 7.0 1.8 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Abhydrolase_6 PF12697.2 KEY65734.1 - 2.1e-37 129.2 0.7 2.4e-37 129.0 0.5 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY65734.1 - 2.9e-14 53.0 0.1 4.3e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY65734.1 - 1.1e-13 51.3 0.0 2.4e-13 50.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KEY65734.1 - 3.5e-06 26.7 0.0 7.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 KEY65734.1 - 0.011 15.6 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Ndr PF03096.9 KEY65734.1 - 0.035 12.5 0.0 0.12 10.7 0.0 1.8 1 1 0 1 1 1 0 Ndr family Lipase_2 PF01674.13 KEY65734.1 - 0.15 11.3 0.0 0.31 10.3 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 2) PFK PF00365.15 KEY65735.1 - 9.3e-163 539.9 2.6 6.2e-118 392.8 1.6 2.1 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.14 KEY65735.1 - 0.11 12.0 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 UvrB/uvrC motif Med17 PF10156.4 KEY65736.1 - 1.8e-77 260.6 0.0 2.3e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex SNF2_N PF00176.18 KEY65737.1 - 4e-65 219.5 0.4 4e-65 219.5 0.3 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEY65737.1 - 1.8e-11 43.7 0.0 3.8e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 KEY65737.1 - 1e-07 31.4 6.0 1.9e-07 30.6 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEY65737.1 - 3e-07 29.9 8.5 6.5e-07 28.9 5.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KEY65737.1 - 6e-06 26.2 0.1 1.6e-05 24.8 0.1 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.1 KEY65737.1 - 7.1e-06 25.7 7.7 1.9e-05 24.4 5.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEY65737.1 - 8.4e-06 25.7 8.0 2e-05 24.5 5.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KEY65737.1 - 0.00047 19.9 8.2 0.0015 18.3 5.7 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KEY65737.1 - 0.0019 17.9 7.9 0.0051 16.5 5.5 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KEY65737.1 - 0.0064 16.1 4.7 0.017 14.8 3.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 KEY65737.1 - 0.035 13.6 5.9 0.72 9.4 4.7 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF86 PF01934.12 KEY65737.1 - 0.045 13.4 0.1 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF86 Baculo_IE-1 PF05290.6 KEY65737.1 - 0.18 11.5 3.5 0.097 12.3 0.8 1.7 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Tmpp129 PF10272.4 KEY65737.1 - 5.2 5.6 8.2 1.9 7.0 3.3 1.9 3 0 0 3 3 3 0 Putative transmembrane protein precursor Phosphodiest PF01663.17 KEY65738.1 - 1.5e-87 294.3 0.4 2e-87 293.9 0.3 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KEY65738.1 - 0.0044 16.2 0.0 0.3 10.2 0.0 2.2 2 0 0 2 2 2 2 Sulfatase Zn_clus PF00172.13 KEY65739.1 - 2.7e-07 30.3 9.0 2.7e-07 30.3 6.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 KEY65740.1 - 1.1e-29 103.3 0.0 1.3e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY65740.1 - 2.1e-20 73.4 0.0 3e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEY65740.1 - 1.8e-05 24.2 0.0 0.00019 20.9 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEY65740.1 - 0.029 13.0 0.0 0.063 11.9 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_76 PF03663.9 KEY65741.1 - 9.4e-152 505.6 11.6 1.2e-151 505.3 8.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KEY65741.1 - 0.15 11.0 4.7 0.17 10.9 0.8 2.6 2 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 Synaptobrevin PF00957.16 KEY65742.1 - 3.6e-34 116.2 0.6 4.1e-34 116.0 0.5 1.0 1 0 0 1 1 1 1 Synaptobrevin EMP24_GP25L PF01105.19 KEY65742.1 - 0.087 12.5 0.0 0.095 12.4 0.0 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF619 PF04768.8 KEY65743.1 - 8.6e-45 152.1 0.0 1.6e-44 151.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) AA_kinase PF00696.23 KEY65743.1 - 4.2e-30 105.0 0.0 6.4e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family p450 PF00067.17 KEY65744.1 - 7.8e-59 199.4 0.0 1e-58 199.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.17 KEY65745.1 - 3.1e-16 58.7 0.0 4.8e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY65745.1 - 1.2e-12 47.5 0.0 1.9e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY65745.1 - 4.6e-08 32.7 0.0 7.6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fasciclin PF02469.17 KEY65746.1 - 1.6e-37 128.3 0.0 1.4e-19 70.3 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Glyco_hydro_16 PF00722.16 KEY65748.1 - 8.5e-19 67.5 1.9 1.8e-18 66.4 1.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.1 KEY65749.1 - 2.1e-46 158.0 5.6 2.1e-46 158.0 3.9 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KEY65749.1 - 2.8e-07 30.5 0.0 5.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KEY65749.1 - 1.6e-05 24.6 0.0 4.3e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KEY65749.1 - 0.0052 16.0 0.0 0.014 14.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF605 PF04652.11 KEY65749.1 - 9.3 5.5 7.7 15 4.8 5.3 1.2 1 0 0 1 1 1 0 Vta1 like ABC_tran PF00005.22 KEY65750.1 - 4.6e-48 162.9 0.0 9.6e-26 90.7 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KEY65750.1 - 1e-13 51.9 5.1 1e-05 25.6 0.6 4.0 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 KEY65750.1 - 3.7e-13 49.2 0.0 5.3e-05 22.5 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KEY65750.1 - 1.1e-07 32.4 0.2 0.0014 18.9 0.0 2.6 3 0 0 3 3 2 2 AAA domain Chromo PF00385.19 KEY65750.1 - 1.2e-07 31.2 0.1 2.5e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.1 KEY65750.1 - 1.5e-07 30.8 0.5 0.0063 16.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KEY65750.1 - 4.7e-07 29.7 0.0 0.007 16.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 KEY65750.1 - 7.7e-07 29.9 0.6 0.012 16.3 0.2 3.2 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 KEY65750.1 - 8.5e-07 28.2 0.0 0.0032 16.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEY65750.1 - 5.9e-06 26.4 0.1 0.16 12.1 0.0 3.7 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 KEY65750.1 - 7.9e-06 25.7 0.0 0.24 11.3 0.0 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 KEY65750.1 - 8.3e-06 25.0 0.0 0.62 9.0 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_10 PF12846.2 KEY65750.1 - 1.9e-05 24.2 1.6 0.39 10.1 0.0 4.0 4 0 0 4 4 4 2 AAA-like domain Miro PF08477.8 KEY65750.1 - 5.3e-05 23.6 0.0 0.08 13.4 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 KEY65750.1 - 0.00017 21.5 0.0 0.0083 16.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KEY65750.1 - 0.00021 21.0 0.0 0.35 10.5 0.1 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KEY65750.1 - 0.00035 20.4 0.0 0.7 9.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 KEY65750.1 - 0.00048 19.8 0.1 0.48 10.0 0.0 2.8 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.12 KEY65750.1 - 0.00055 19.8 0.5 0.32 10.7 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_18 PF13238.1 KEY65750.1 - 0.00069 19.9 0.0 0.057 13.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KEY65750.1 - 0.00084 19.4 0.0 2.1 8.5 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 KEY65750.1 - 0.0015 17.9 0.0 1.3 8.3 0.0 3.1 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 KEY65750.1 - 0.0028 16.4 0.3 0.7 8.6 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA_13 PF13166.1 KEY65750.1 - 0.0046 15.4 0.0 1.5 7.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KEY65750.1 - 0.0073 15.9 0.2 5.7 6.4 0.0 3.3 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 KEY65750.1 - 0.0076 16.4 0.0 4.9 7.3 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEY65750.1 - 0.0085 16.0 0.7 1.8 8.5 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain PduV-EutP PF10662.4 KEY65750.1 - 0.017 14.6 0.0 1.4 8.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 KEY65750.1 - 0.017 14.9 0.0 0.72 9.6 0.0 2.9 2 1 0 2 2 2 0 Dynamin family DUF3584 PF12128.3 KEY65750.1 - 0.021 12.1 1.5 1.8 5.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_14 PF13173.1 KEY65750.1 - 0.028 14.3 0.0 3.9 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KEY65750.1 - 0.03 13.8 0.1 5.5 6.4 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family CLASP_N PF12348.3 KEY65750.1 - 0.045 13.1 0.0 3.9 6.7 0.0 2.9 3 0 0 3 3 3 0 CLASP N terminal DUF815 PF05673.8 KEY65750.1 - 0.047 12.6 0.0 2.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 KEY65750.1 - 0.049 13.3 0.4 7.1 6.2 0.0 2.9 4 0 0 4 4 2 0 Archaeal ATPase MutS_V PF00488.16 KEY65750.1 - 0.067 12.5 0.1 6.3 6.1 0.0 2.4 2 0 0 2 2 2 0 MutS domain V cobW PF02492.14 KEY65750.1 - 0.089 12.2 0.0 18 4.7 0.0 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain zf-DHHC PF01529.15 KEY65751.1 - 6.1e-41 139.6 1.4 1.7e-40 138.2 1.0 1.8 1 1 0 1 1 1 1 DHHC palmitoyltransferase DUF4366 PF14283.1 KEY65752.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) HAD PF12710.2 KEY65753.1 - 5.7e-17 62.5 0.1 8.3e-17 61.9 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEY65753.1 - 9.4e-10 39.2 2.0 4.4e-08 33.8 1.4 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEY65753.1 - 3.8e-08 33.2 2.3 4.3e-07 29.7 0.1 2.8 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase DUF705 PF05152.7 KEY65753.1 - 0.00035 19.6 0.2 0.00051 19.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) HAD_2 PF13419.1 KEY65753.1 - 0.00041 20.6 0.0 0.0011 19.2 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase PAPS_reduct PF01507.14 KEY65754.1 - 1.6e-42 145.2 0.0 2.5e-42 144.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF2399 PF09664.5 KEY65754.1 - 0.077 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) TYW3 PF02676.9 KEY65755.1 - 8.7e-66 220.9 0.0 1.1e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF1690 PF07956.6 KEY65756.1 - 6.7e-24 84.4 4.5 8.7e-24 84.1 3.1 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Lebercilin PF15619.1 KEY65756.1 - 0.0013 18.2 5.9 0.0017 17.8 4.1 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Lzipper-MIP1 PF14389.1 KEY65756.1 - 0.021 14.8 4.1 0.047 13.8 0.4 2.4 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Retrotrans_gag PF03732.12 KEY65756.1 - 0.063 13.3 1.7 0.13 12.3 1.0 1.8 1 1 0 1 1 1 0 Retrotransposon gag protein Uso1_p115_C PF04871.8 KEY65756.1 - 0.066 13.1 7.8 0.11 12.4 5.1 1.5 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2514 PF10721.4 KEY65756.1 - 0.086 12.5 7.2 0.12 12.0 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Ferric_reduct PF01794.14 KEY65757.1 - 1.3e-20 73.7 6.3 1.3e-20 73.7 4.4 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KEY65757.1 - 1.5e-18 67.2 0.0 9.4e-16 58.0 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KEY65757.1 - 4.5e-11 42.5 0.0 2.1e-10 40.4 0.0 2.1 1 1 0 1 1 1 1 FAD-binding domain TP_methylase PF00590.15 KEY65758.1 - 6.7e-45 153.3 0.8 1.4e-44 152.2 0.5 1.6 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 KEY65758.1 - 2.4e-13 50.2 0.0 4.4e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KEY65758.1 - 7.9e-08 31.5 0.1 5.6e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KEY65758.1 - 3e-05 22.8 0.0 6e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Rsm22 PF09243.5 KEY65759.1 - 1.4e-31 109.5 0.1 1.2e-30 106.4 0.0 2.5 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_18 PF12847.2 KEY65759.1 - 0.017 15.6 0.1 0.085 13.4 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 KEY65759.1 - 0.019 15.4 0.0 0.048 14.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Thioredoxin PF00085.15 KEY65760.1 - 2e-26 91.6 0.0 2.7e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KEY65760.1 - 6e-06 26.2 0.0 9.3e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KEY65760.1 - 8.6e-05 22.7 0.1 0.00047 20.3 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 KEY65760.1 - 0.0017 18.0 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 KEY65760.1 - 0.015 14.8 0.0 0.019 14.5 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.5 KEY65760.1 - 0.028 13.9 0.0 0.064 12.8 0.0 1.5 1 1 0 1 1 1 0 Redoxin Thioredoxin_7 PF13899.1 KEY65760.1 - 0.029 14.3 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Methyltrn_RNA_3 PF02598.12 KEY65761.1 - 3.8e-83 279.1 0.0 4.3e-83 279.0 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Pectate_lyase_3 PF12708.2 KEY65762.1 - 1.5e-64 218.2 7.7 1.2e-54 185.8 0.9 2.6 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KEY65762.1 - 2.5e-06 26.8 1.3 0.039 13.4 0.1 2.5 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Radical_SAM PF04055.16 KEY65763.1 - 1.6e-14 54.4 0.0 2.4e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Methyltransf_11 PF08241.7 KEY65764.1 - 6.8e-14 52.1 0.0 1.7e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY65764.1 - 6e-12 46.1 0.1 5.5e-11 43.0 0.0 2.2 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY65764.1 - 9.2e-12 45.2 0.0 4.4e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY65764.1 - 1.6e-09 37.5 0.0 2.4e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY65764.1 - 1e-08 35.5 0.0 2.3e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY65764.1 - 3.3e-08 33.5 0.2 1.4e-07 31.4 0.1 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY65764.1 - 1.1e-07 31.6 0.0 1.6e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY65764.1 - 1.2e-06 27.7 0.0 1.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KEY65764.1 - 7.3e-06 25.4 0.0 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 KEY65764.1 - 7.6e-05 21.9 0.0 9.7e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 KEY65764.1 - 0.0037 16.4 0.0 0.01 15.0 0.0 1.7 1 1 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 KEY65764.1 - 0.0055 15.7 0.0 0.0069 15.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_24 PF13578.1 KEY65764.1 - 0.023 15.5 0.0 0.38 11.6 0.0 2.4 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.4 KEY65764.1 - 0.024 14.1 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase AATF-Che1 PF13339.1 KEY65765.1 - 1.3 9.1 7.2 9 6.4 1.9 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor PrpF PF04303.8 KEY65766.1 - 4.5e-108 361.2 0.4 5.3e-108 361.0 0.3 1.0 1 0 0 1 1 1 1 PrpF protein Uroplakin_II PF07353.7 KEY65766.1 - 0.0036 16.6 0.0 0.0069 15.7 0.0 1.4 1 0 0 1 1 1 1 Uroplakin II DUF3374 PF11854.3 KEY65767.1 - 0.0088 14.3 0.7 0.0099 14.1 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3374) Herpes_BLLF1 PF05109.8 KEY65767.1 - 0.046 11.7 8.6 0.05 11.5 6.0 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) AJAP1_PANP_C PF15298.1 KEY65767.1 - 0.34 10.7 6.5 0.41 10.5 4.5 1.1 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Mucin PF01456.12 KEY65767.1 - 2 8.1 13.4 2.4 7.9 9.3 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein BLVR PF06375.6 KEY65768.1 - 0.062 13.1 5.3 0.11 12.3 1.0 2.1 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) PBP1_TM PF14812.1 KEY65768.1 - 0.063 13.5 0.2 0.063 13.5 0.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PLD_C PF12357.3 KEY65768.1 - 0.071 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Phospholipase D C terminal TATR PF03430.8 KEY65768.1 - 0.71 8.4 2.8 1 7.9 2.0 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator YqzE PF14038.1 KEY65768.1 - 8.8 6.1 7.0 0.38 10.5 0.8 1.8 2 0 0 2 2 2 0 YqzE-like protein SRP72 PF08492.7 KEY65769.1 - 2.9e-15 56.3 8.2 2.9e-15 56.3 5.7 2.5 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_11 PF13414.1 KEY65769.1 - 1.6e-06 27.6 18.2 0.0034 16.9 0.2 5.3 4 1 2 6 6 6 2 TPR repeat Apc3 PF12895.2 KEY65769.1 - 8.4e-05 22.6 12.7 0.0028 17.7 1.9 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KEY65769.1 - 0.00011 21.8 23.0 0.69 9.9 0.2 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEY65769.1 - 0.0014 18.5 21.8 0.22 11.4 0.6 6.0 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEY65769.1 - 0.0015 19.1 32.5 0.012 16.2 6.5 6.0 4 2 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEY65769.1 - 0.0067 16.9 31.4 4.5 8.1 0.8 8.4 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEY65769.1 - 0.024 14.9 37.6 0.049 13.9 2.4 7.1 4 3 4 8 8 8 0 Tetratricopeptide repeat PPR PF01535.15 KEY65769.1 - 0.15 12.1 0.7 60 3.9 0.0 4.0 4 0 0 4 4 4 0 PPR repeat TPR_6 PF13174.1 KEY65769.1 - 1.6 9.3 19.2 27 5.4 0.5 6.7 6 1 0 6 6 6 0 Tetratricopeptide repeat Sec7 PF01369.15 KEY65770.1 - 6.2e-40 136.9 0.0 1.3e-39 135.8 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 KEY65770.1 - 0.0018 18.4 0.0 0.0041 17.2 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 KEY65770.1 - 0.0019 18.3 0.0 0.0045 17.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Peptidase_M14 PF00246.19 KEY65771.1 - 2e-65 221.2 0.0 2.5e-65 220.8 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase MAPEG PF01124.13 KEY65772.1 - 4.2e-20 71.6 1.3 5.1e-20 71.3 0.9 1.1 1 0 0 1 1 1 1 MAPEG family DNA_pol_B_palm PF14792.1 KEY65773.1 - 1.5e-21 76.5 0.0 2.8e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 KEY65773.1 - 3.5e-19 68.2 0.0 6.3e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 KEY65773.1 - 3.2e-11 42.5 0.1 7.4e-11 41.4 0.1 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 KEY65773.1 - 5.4e-05 23.2 0.0 0.00013 22.0 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain MBD PF01429.14 KEY65773.1 - 0.028 13.9 0.0 0.069 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyl-CpG binding domain NTP_transf_2 PF01909.18 KEY65773.1 - 0.028 14.7 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain SMC_N PF02463.14 KEY65774.1 - 6e-50 169.5 32.1 1.8e-49 167.9 22.2 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KEY65774.1 - 4.2e-26 91.2 0.0 2.2e-25 88.9 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KEY65774.1 - 2.2e-09 37.6 7.7 0.00023 21.2 0.1 3.1 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KEY65774.1 - 2.4e-08 33.3 0.0 6.5e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 KEY65774.1 - 4.7e-05 22.7 28.8 0.061 12.5 1.2 5.5 3 2 3 6 6 6 4 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 KEY65774.1 - 6.7e-05 22.6 14.4 6.7e-05 22.6 10.0 8.8 4 3 6 10 10 10 1 TPR/MLP1/MLP2-like protein AAA_13 PF13166.1 KEY65774.1 - 0.92 7.8 115.1 0.16 10.3 14.4 6.4 5 2 2 7 7 7 0 AAA domain Spc7 PF08317.6 KEY65774.1 - 1 7.9 111.6 0.034 12.8 14.2 6.8 3 2 4 7 7 7 0 Spc7 kinetochore protein DASH_Dam1 PF08653.5 KEY65774.1 - 3.9 7.3 4.7 15 5.4 0.1 4.0 4 0 0 4 4 4 0 DASH complex subunit Dam1 DUF2838 PF10998.3 KEY65775.1 - 1.1e-44 150.8 9.6 1.1e-44 150.8 6.7 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Not3 PF04065.10 KEY65775.1 - 0.26 10.5 2.3 0.4 9.9 1.6 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component WD40 PF00400.27 KEY65776.1 - 3.5e-33 112.2 11.8 5.1e-07 29.3 0.0 6.4 6 1 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KEY65776.1 - 9.1e-08 32.0 0.0 0.0014 18.3 0.0 3.0 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A STAG PF08514.6 KEY65777.1 - 0.082 12.6 0.2 0.082 12.6 0.2 1.5 2 0 0 2 2 2 0 STAG domain Acetyltransf_1 PF00583.19 KEY65778.1 - 1.3e-16 60.3 0.0 1.8e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEY65778.1 - 1e-06 28.8 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEY65778.1 - 7.3e-06 26.0 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEY65778.1 - 1.2e-05 24.9 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 KEY65778.1 - 7.2e-05 22.7 0.1 9.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KEY65778.1 - 0.022 14.7 0.1 0.042 13.7 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1793 PF08760.6 KEY65779.1 - 5.6e-72 241.1 0.4 1e-71 240.2 0.2 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) RRM_1 PF00076.17 KEY65780.1 - 1.7e-20 72.3 0.0 2.5e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY65780.1 - 1.3e-15 57.0 0.0 2e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY65780.1 - 1.2e-11 44.3 0.0 1.8e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec39 PF08314.6 KEY65781.1 - 4.2e-196 653.0 0.0 5.2e-196 652.7 0.0 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.4 KEY65782.1 - 9.1e-05 22.3 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 KEY65782.1 - 0.067 13.3 0.6 0.14 12.3 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) COX6B PF02297.12 KEY65782.1 - 0.11 12.4 1.7 0.18 11.8 1.2 1.4 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb ABC_tran_2 PF12848.2 KEY65783.1 - 0.053 13.3 3.2 0.092 12.5 2.2 1.3 1 0 0 1 1 1 0 ABC transporter TPR_MLP1_2 PF07926.7 KEY65783.1 - 0.61 9.8 4.6 0.92 9.2 3.2 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Myb_DNA-binding PF00249.26 KEY65785.1 - 6.7e-21 74.0 1.8 2.7e-11 43.3 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEY65785.1 - 2.1e-14 53.3 0.9 5e-08 32.9 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2774 PF11242.3 KEY65785.1 - 0.018 15.0 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) MADF_DNA_bdg PF10545.4 KEY65785.1 - 0.079 13.1 4.5 0.2 11.8 1.2 2.2 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Glyco_transf_41 PF13844.1 KEY65786.1 - 7e-95 317.7 0.0 9.7e-49 165.5 0.0 3.2 2 1 1 3 3 3 2 Glycosyl transferase family 41 TPR_1 PF00515.23 KEY65786.1 - 1.8e-22 77.9 5.9 1.7e-05 24.2 0.0 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 KEY65786.1 - 1.6e-20 72.5 10.9 3.3e-06 26.6 0.0 5.6 3 2 1 5 5 5 4 TPR repeat TPR_2 PF07719.12 KEY65786.1 - 5.7e-19 66.4 5.5 0.0033 17.2 0.1 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 KEY65786.1 - 2.2e-12 45.7 1.0 0.0014 18.2 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEY65786.1 - 1.7e-11 43.9 10.2 2.9e-06 27.1 0.3 4.7 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 KEY65786.1 - 8e-11 41.2 0.5 0.0038 17.3 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEY65786.1 - 1.5e-10 40.7 8.6 0.021 15.4 0.0 5.6 4 2 2 6 6 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEY65786.1 - 3e-08 34.1 8.1 0.095 13.4 0.0 5.4 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 KEY65786.1 - 1.5e-06 27.9 8.3 0.94 9.5 0.2 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEY65786.1 - 5e-06 26.7 1.5 1 9.7 0.0 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KEY65786.1 - 4.7e-05 23.4 0.3 0.12 12.5 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KEY65786.1 - 0.00012 21.6 4.5 1.1 9.1 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 KEY65786.1 - 0.00065 18.8 0.1 0.32 10.0 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEY65786.1 - 0.1 13.0 1.9 72 4.1 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat Sel1 PF08238.7 KEY65786.1 - 0.17 12.5 3.5 3.3 8.4 0.1 4.1 3 1 0 3 3 3 0 Sel1 repeat NARP1 PF12569.3 KEY65786.1 - 0.32 9.6 0.0 9.8 4.7 0.1 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_9 PF13371.1 KEY65786.1 - 0.69 9.8 5.6 2.3 8.1 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L11_N PF03946.9 KEY65787.1 - 4.4e-18 64.4 0.1 7.3e-18 63.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KEY65787.1 - 5.9e-12 45.5 0.2 9.9e-12 44.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Sec23_trunk PF04811.10 KEY65788.1 - 2.3e-79 266.1 0.0 3.2e-79 265.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KEY65788.1 - 2.2e-34 116.9 0.2 6.2e-34 115.5 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KEY65788.1 - 2.1e-30 105.0 0.1 4.5e-30 104.0 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KEY65788.1 - 1.6e-16 59.5 7.0 3.1e-16 58.6 4.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KEY65788.1 - 1.2e-12 47.3 0.0 2.8e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat tRNA-synt_1 PF00133.17 KEY65790.1 - 3.7e-152 507.4 0.0 5.9e-152 506.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KEY65790.1 - 1.5e-22 79.7 0.0 1.4e-12 47.0 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KEY65790.1 - 5.6e-18 65.1 0.0 1.1e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 KEY65790.1 - 0.025 14.1 4.8 0.052 13.2 3.3 1.5 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.14 KEY65790.1 - 0.027 13.6 0.0 1.5 7.8 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain SET PF00856.23 KEY65792.1 - 4.6e-06 27.0 0.2 0.081 13.2 0.1 3.1 3 1 0 3 3 3 2 SET domain FG-GAP PF01839.18 KEY65792.1 - 0.03 14.0 1.9 9.5 6.0 0.0 3.5 3 0 0 3 3 3 0 FG-GAP repeat mono-CXXC PF15626.1 KEY65792.1 - 0.03 14.2 3.2 0.086 12.7 2.2 1.8 1 0 0 1 1 1 0 single CXXC unit zf-MYND PF01753.13 KEY65792.1 - 5.3 7.0 15.2 0.09 12.6 4.9 2.3 2 0 0 2 2 2 0 MYND finger CH PF00307.26 KEY65793.1 - 5.1e-12 45.7 0.0 7.9e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 KEY65793.1 - 0.031 14.3 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 CDC24 Calponin CAMSAP_CH PF11971.3 KEY65793.1 - 0.2 11.3 0.0 0.38 10.4 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain NDUFA12 PF05071.11 KEY65794.1 - 6.6e-14 52.2 0.9 6.6e-14 52.2 0.6 1.6 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 HABP4_PAI-RBP1 PF04774.10 KEY65797.1 - 3.8e-07 30.5 6.3 3.8e-07 30.5 4.4 2.9 4 0 0 4 4 4 1 Hyaluronan / mRNA binding family Stm1_N PF09598.5 KEY65797.1 - 3.9e-05 24.2 3.5 3.9e-05 24.2 2.5 4.8 4 2 0 4 4 4 1 Stm1 DUF1010 PF06231.6 KEY65798.1 - 0.0034 17.3 0.1 0.0056 16.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1010) PHD PF00628.24 KEY65799.1 - 3.1e-10 39.5 5.9 5e-10 38.9 4.1 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KEY65799.1 - 0.12 11.6 1.4 0.21 10.9 1.0 1.3 1 0 0 1 1 1 0 PHD-finger DUF4451 PF14616.1 KEY65800.1 - 8.7e-36 122.4 0.6 1.6e-35 121.6 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Actin PF00022.14 KEY65803.1 - 5.8e-30 103.9 0.0 4.4e-20 71.4 0.0 3.0 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 KEY65803.1 - 0.2 10.1 0.0 0.7 8.4 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein MFS_1 PF07690.11 KEY65804.1 - 1.6e-24 86.2 27.6 6.1e-13 48.2 4.7 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 KEY65804.1 - 6.8e-07 28.0 19.1 1.8e-05 23.3 2.7 4.1 3 1 0 3 3 3 3 MFS/sugar transport protein LacY_symp PF01306.14 KEY65804.1 - 0.54 8.7 12.9 0.065 11.7 2.5 2.8 3 0 0 3 3 3 0 LacY proton/sugar symporter MFS_1_like PF12832.2 KEY65804.1 - 1.7 8.4 14.5 1.5 8.6 0.1 4.2 5 0 0 5 5 5 0 MFS_1 like family TraL PF07178.6 KEY65804.1 - 2.9 7.9 5.9 8.2 6.5 0.0 3.2 3 0 0 3 3 3 0 TraL protein Med10 PF09748.4 KEY65806.1 - 1.9e-39 134.3 0.1 2.3e-39 134.1 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex TPR_11 PF13414.1 KEY65807.1 - 7.1e-51 169.7 13.9 1.9e-22 78.6 0.8 6.4 4 2 1 6 6 6 4 TPR repeat TPR_2 PF07719.12 KEY65807.1 - 3.8e-37 123.2 7.1 1.4e-05 24.6 0.1 8.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.23 KEY65807.1 - 3.9e-34 114.8 7.1 1.2e-07 30.9 0.1 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 KEY65807.1 - 1.3e-28 98.9 3.3 2.2e-09 37.7 0.1 6.2 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 KEY65807.1 - 1e-27 96.2 13.8 2.2e-09 37.5 0.0 6.1 4 3 2 6 6 5 5 Tetratricopeptide repeat DnaJ PF00226.26 KEY65807.1 - 2.8e-27 94.2 2.8 1e-26 92.4 1.9 2.1 1 0 0 1 1 1 1 DnaJ domain TPR_14 PF13428.1 KEY65807.1 - 9.8e-23 78.5 8.6 7e-05 23.1 0.4 8.8 4 3 5 9 9 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 KEY65807.1 - 1.2e-19 70.0 6.8 3.2e-06 26.9 0.6 5.1 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 KEY65807.1 - 1.5e-17 62.2 10.1 0.0011 18.9 0.0 7.0 6 0 0 6 6 5 4 Tetratricopeptide repeat Apc3 PF12895.2 KEY65807.1 - 2.1e-16 59.8 1.1 2.4e-08 33.9 0.0 3.6 2 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KEY65807.1 - 3.3e-16 58.9 1.3 5.8e-06 26.0 0.0 5.1 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEY65807.1 - 4.6e-16 57.3 10.2 0.015 14.9 0.2 8.1 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 KEY65807.1 - 8.4e-12 43.9 2.2 0.1 12.4 0.0 6.9 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 KEY65807.1 - 1.6e-10 40.7 16.7 0.26 11.8 0.0 8.6 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_15 PF13429.1 KEY65807.1 - 2.3e-09 36.7 5.5 0.0024 16.9 0.0 4.5 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 KEY65807.1 - 4.8e-06 26.4 0.1 0.44 11.1 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat Coatomer_E PF04733.9 KEY65807.1 - 2.2e-05 23.7 0.3 0.023 13.9 0.0 3.1 3 1 1 4 4 4 1 Coatomer epsilon subunit Alkyl_sulf_dimr PF14863.1 KEY65807.1 - 4e-05 23.8 1.5 0.89 9.7 0.0 3.5 2 1 1 3 3 3 2 Alkyl sulfatase dimerisation TPR_20 PF14561.1 KEY65807.1 - 6.9e-05 22.8 2.3 2.7 8.1 0.0 5.0 2 2 1 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.12 KEY65807.1 - 7.1e-05 23.1 5.7 0.86 9.8 0.1 4.9 3 2 3 6 6 6 2 Bacterial transcriptional activator domain SNAP PF14938.1 KEY65807.1 - 0.00034 19.8 2.1 0.091 11.8 0.1 2.5 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP YfiO PF13525.1 KEY65807.1 - 0.0014 18.1 3.9 0.013 14.9 0.3 2.5 2 0 0 2 2 2 1 Outer membrane lipoprotein MIT PF04212.13 KEY65807.1 - 0.021 14.6 3.5 3.4 7.6 0.0 4.1 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain NatB_MDM20 PF09797.4 KEY65807.1 - 0.034 12.8 0.0 0.069 11.8 0.0 1.5 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_10 PF13374.1 KEY65807.1 - 0.13 12.2 8.8 7.1 6.7 0.3 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat ChAPs PF09295.5 KEY65807.1 - 0.13 10.9 0.2 0.93 8.1 0.0 2.2 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) EF-hand_6 PF13405.1 KEY65808.1 - 1.1e-11 43.6 2.0 2.2e-05 23.9 0.2 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KEY65808.1 - 7.8e-09 34.2 1.4 0.0029 16.7 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KEY65808.1 - 2.7e-07 30.6 0.0 0.0073 16.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KEY65808.1 - 1.1e-05 24.4 4.7 0.046 13.0 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KEY65808.1 - 0.00017 21.1 1.5 0.062 12.9 0.0 2.9 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 KEY65808.1 - 0.078 12.9 0.0 5.6 6.9 0.0 2.5 2 1 0 2 2 2 0 EF-hand domain Afi1 PF07792.7 KEY65809.1 - 4.2e-59 198.7 0.0 9.4e-59 197.5 0.0 1.6 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 KEY65809.1 - 3e-36 123.5 0.0 5.4e-36 122.7 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KEY65809.1 - 1.9e-06 26.6 0.1 0.079 11.4 0.0 3.5 3 1 1 4 4 4 2 Transport protein Avl9 CENP-B_dimeris PF09026.5 KEY65809.1 - 0.0031 17.7 2.6 0.0031 17.7 1.8 2.2 2 0 0 2 2 2 1 Centromere protein B dimerisation domain DUF2347 PF09804.4 KEY65809.1 - 0.053 12.8 0.0 0.42 9.8 0.0 2.5 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2347) DUF1168 PF06658.7 KEY65809.1 - 0.11 12.0 8.3 0.23 10.9 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) FLO_LFY PF01698.11 KEY65809.1 - 0.42 9.4 4.5 0.68 8.7 3.1 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Cwf_Cwc_15 PF04889.7 KEY65809.1 - 0.92 9.1 16.5 2 8.0 11.4 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Esterase PF00756.15 KEY65810.1 - 1.3e-51 175.4 0.0 1.6e-51 175.2 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KEY65810.1 - 8e-05 22.4 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KEY65810.1 - 0.0001 21.6 0.0 0.00085 18.6 0.0 2.0 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.2 KEY65810.1 - 0.00026 20.9 0.0 0.00058 19.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEY65810.1 - 0.0035 16.5 0.0 0.0052 16.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 KEY65810.1 - 0.023 13.5 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.20 KEY65810.1 - 0.034 13.7 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 KEY65810.1 - 0.042 13.2 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 KEY65810.1 - 0.07 12.6 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 KEY65810.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein AXE1 PF05448.7 KEY65810.1 - 0.12 10.8 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DLH PF01738.13 KEY65810.1 - 0.15 11.3 0.0 0.27 10.4 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family RNA_pol_Rpb6 PF01192.17 KEY65812.1 - 1.2e-24 85.7 0.3 1.9e-24 85.1 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Pox_RNA_Pol_19 PF05320.7 KEY65812.1 - 0.12 12.1 2.5 0.25 11.0 1.7 1.5 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit zf-C2H2 PF00096.21 KEY65813.1 - 3.7e-29 99.2 58.4 1.8e-05 24.7 1.3 10.6 10 1 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY65813.1 - 5.1e-28 95.3 50.6 0.0012 18.9 0.7 10.4 10 0 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEY65813.1 - 7.6e-17 60.6 52.4 0.00031 20.8 0.1 11.0 11 1 0 11 11 11 5 Zinc-finger double domain zf-met PF12874.2 KEY65813.1 - 2.9e-06 27.2 11.4 0.76 10.0 0.1 7.3 7 0 0 7 7 7 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KEY65813.1 - 0.025 14.7 43.5 0.032 14.3 1.9 7.4 6 1 2 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 KEY65813.1 - 0.031 14.5 1.4 0.031 14.5 1.0 9.5 9 3 1 10 10 10 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 KEY65813.1 - 0.036 14.2 32.2 1.8 8.7 0.1 8.4 10 0 0 10 10 9 0 Zinc-finger double-stranded RNA-binding CHORD PF04968.7 KEY65813.1 - 0.28 11.4 19.9 6.1 7.1 1.0 6.0 5 2 2 7 7 7 0 CHORD zf-C2H2_6 PF13912.1 KEY65813.1 - 2.9 7.9 18.1 4 7.4 0.5 5.7 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KEY65813.1 - 3 7.9 33.8 12 6.0 0.4 5.9 3 2 4 7 7 7 0 C2H2 type zinc-finger (2 copies) IBR PF01485.16 KEY65813.1 - 6.5 6.7 30.9 0.87 9.5 3.0 5.6 2 2 1 3 3 3 0 IBR domain Zip PF02535.17 KEY65814.1 - 2e-33 115.7 11.5 1.2e-32 113.2 8.0 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3592 PF12158.3 KEY65814.1 - 0.085 12.6 2.9 0.38 10.5 2.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) Endonuclease_NS PF01223.18 KEY65815.1 - 4.3e-59 199.6 0.0 5.8e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease WD40 PF00400.27 KEY65816.1 - 3.4e-49 163.0 22.2 5.1e-09 35.6 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KEY65816.1 - 0.0011 18.6 0.0 0.42 10.3 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KEY65816.1 - 0.02 13.6 0.2 0.14 10.8 0.1 2.4 1 1 0 2 2 2 0 Nup133 N terminal like MBOAT PF03062.14 KEY65817.1 - 1.1e-18 67.4 12.3 1.1e-18 67.4 8.5 2.6 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KEY65817.1 - 0.00019 21.4 2.1 0.00064 19.7 1.5 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ICMT PF04140.9 KEY65818.1 - 2.2e-27 95.1 1.1 2.9e-27 94.7 0.1 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KEY65818.1 - 1.3e-12 47.6 1.7 1.3e-12 47.6 1.2 2.3 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 KEY65818.1 - 0.0086 15.4 0.2 0.013 14.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Tmemb_170 PF10190.4 KEY65819.1 - 4.8e-06 26.5 5.8 6e-06 26.2 4.0 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 PI-PLC-X PF00388.14 KEY65823.1 - 4.2e-60 201.3 0.0 6.6e-60 200.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KEY65823.1 - 8.9e-39 132.1 0.0 1.8e-38 131.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain NRDE-2 PF08424.5 KEY65824.1 - 3e-82 276.0 4.5 1e-80 271.0 0.4 2.8 3 0 0 3 3 3 2 NRDE-2, necessary for RNA interference adh_short PF00106.20 KEY65825.1 - 3.8e-25 88.7 0.1 4.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY65825.1 - 3.8e-13 49.7 0.0 5e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY65825.1 - 5.9e-12 45.6 0.0 8.4e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KEY65825.1 - 0.00015 21.9 0.1 0.00028 21.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KEY65825.1 - 0.00049 20.1 0.1 0.0019 18.2 0.1 1.9 2 0 0 2 2 2 1 NADH(P)-binding F420_oxidored PF03807.12 KEY65825.1 - 0.064 13.6 0.0 0.18 12.2 0.1 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KEY65825.1 - 0.07 12.7 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ATP-synt_ab PF00006.20 KEY65825.1 - 0.074 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NAD_binding_7 PF13241.1 KEY65825.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Eno-Rase_NADH_b PF12242.3 KEY65825.1 - 0.22 11.3 1.2 0.64 9.8 0.2 2.0 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Urb2 PF10441.4 KEY65826.1 - 5.6e-54 183.0 0.0 3e-53 180.7 0.0 2.3 1 0 0 1 1 1 1 Urb2/Npa2 family DUF543 PF04418.7 KEY65827.1 - 1.1e-28 98.9 0.0 1.2e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Zn_clus PF00172.13 KEY65828.1 - 0.00031 20.5 13.6 0.00055 19.7 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 KEY65831.1 - 0.0053 16.9 11.2 0.086 13.2 0.1 3.2 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY65831.1 - 0.077 13.3 5.9 2.5 8.6 0.0 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type TIM PF00121.13 KEY65832.1 - 1.4e-89 299.3 0.1 1.6e-89 299.1 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase L51_S25_CI-B8 PF05047.11 KEY65833.1 - 2.4e-12 46.3 0.0 4.2e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF187 PF02638.10 KEY65833.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.5 1 1 1 2 2 2 0 Glycosyl hydrolase like GH101 U1snRNP70_N PF12220.3 KEY65834.1 - 4.4e-30 103.8 3.5 8.1e-30 103.0 2.4 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 KEY65834.1 - 6.1e-17 61.0 0.0 3.7e-16 58.4 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY65834.1 - 8.2e-13 48.1 0.0 1.6e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY65834.1 - 2e-09 37.1 0.0 5.5e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L10 PF00466.15 KEY65835.1 - 1.1e-19 70.1 0.0 1.6e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 NTF2 PF02136.15 KEY65836.1 - 1.4e-20 73.8 0.1 2.3e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 KEY65836.1 - 2.7e-11 42.9 0.1 5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY65836.1 - 6.9e-09 35.5 0.0 1.4e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY65836.1 - 1.1e-06 28.3 0.0 2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KEY65836.1 - 1.3e-05 25.0 0.0 4.8e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 RNA binding motif TT_ORF2a PF08197.6 KEY65839.1 - 0.37 10.5 2.9 4.3 7.1 0.4 2.8 3 0 0 3 3 3 0 pORF2a truncated protein TSC22 PF01166.13 KEY65840.1 - 0.074 13.0 0.3 0.17 11.8 0.2 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family TPR_MLP1_2 PF07926.7 KEY65840.1 - 0.13 12.0 6.4 0.34 10.6 4.4 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Amidase PF01425.16 KEY65841.1 - 1.7e-32 112.8 1.2 2.6e-32 112.2 0.8 1.2 1 0 0 1 1 1 1 Amidase Autophagy_N PF03986.8 KEY65842.1 - 4.3e-47 159.5 1.6 6e-47 159.0 0.0 1.8 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 KEY65842.1 - 5.7e-22 77.6 0.3 1.2e-21 76.6 0.2 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 KEY65842.1 - 1.4e-14 52.8 0.4 2.5e-14 52.0 0.3 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal PBP1_TM PF14812.1 KEY65842.1 - 1.3 9.3 6.0 0.9 9.8 1.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C3HC4_2 PF13923.1 KEY65843.1 - 1.4e-08 34.5 9.3 2.4e-08 33.8 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEY65843.1 - 6.2e-08 32.1 4.9 1e-07 31.5 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 KEY65843.1 - 1.3e-07 31.1 2.4 2.5e-07 30.2 1.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4 PF00097.20 KEY65843.1 - 2.3e-07 30.3 8.3 4e-07 29.5 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY65843.1 - 5.1e-07 29.3 7.4 8.5e-07 28.5 5.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KEY65843.1 - 2.6e-06 27.1 7.7 4.3e-06 26.4 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KEY65843.1 - 0.00082 19.0 3.0 0.0023 17.6 2.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KEY65843.1 - 0.0048 16.7 8.2 0.012 15.5 5.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Cript PF10235.4 KEY65843.1 - 0.021 15.1 0.5 0.075 13.3 0.4 2.0 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT Harakiri PF15196.1 KEY65843.1 - 0.092 13.0 0.9 0.26 11.5 0.6 1.8 1 0 0 1 1 1 0 Activator of apoptosis harakiri zf-Nse PF11789.3 KEY65843.1 - 0.096 12.2 2.4 0.18 11.3 1.7 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit tRNA-synt_1d PF00750.14 KEY65844.1 - 4.9e-74 249.2 0.1 1.1e-73 248.0 0.1 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KEY65844.1 - 8.9e-22 77.2 0.0 2.1e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 KEY65844.1 - 0.052 14.0 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain DUF3638 PF12340.3 KEY65845.1 - 1.2e-98 328.6 0.2 2.3e-98 327.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 KEY65845.1 - 3.8e-14 51.4 0.2 1.1e-13 50.0 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) eIF-3c_N PF05470.7 KEY65845.1 - 0.49 8.4 0.0 0.78 7.7 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Mcp5_PH PF12814.2 KEY65846.1 - 1.8e-41 140.9 0.1 4.6e-41 139.5 0.0 1.8 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology IncA PF04156.9 KEY65846.1 - 0.0011 18.6 35.7 0.069 12.7 2.1 3.8 4 1 0 4 4 4 3 IncA protein PH PF00169.24 KEY65846.1 - 0.0076 16.4 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 PH domain THOC7 PF05615.8 KEY65846.1 - 5.7 7.2 18.5 20 5.4 0.0 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 DUF2404 PF10296.4 KEY65847.1 - 1.3e-28 98.9 0.1 3e-28 97.7 0.1 1.7 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) YkuD PF03734.9 KEY65847.1 - 0.056 13.7 0.0 0.36 11.1 0.0 2.3 1 1 1 2 2 2 0 L,D-transpeptidase catalytic domain PH PF00169.24 KEY65847.1 - 0.065 13.4 0.0 0.23 11.6 0.0 1.9 1 0 0 1 1 1 0 PH domain DNA_pol_B PF00136.16 KEY65848.1 - 1.3e-93 314.3 0.0 2.1e-93 313.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KEY65848.1 - 1.4e-20 73.4 0.1 1.4e-09 37.3 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KEY65848.1 - 8.2e-19 67.3 5.6 2e-18 66.1 3.9 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta HypA PF01155.14 KEY65848.1 - 1.5 8.5 5.0 21 4.8 0.5 2.7 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Slu7 PF11708.3 KEY65849.1 - 6.6e-78 261.7 20.8 6.6e-78 261.7 14.4 2.4 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 KEY65849.1 - 0.02 14.5 0.6 0.04 13.5 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Capsule_synth PF05159.9 KEY65849.1 - 0.06 12.8 2.9 0.11 11.8 0.1 2.3 2 0 0 2 2 2 0 Capsule polysaccharide biosynthesis protein Ribosomal_S4 PF00163.14 KEY65850.1 - 3.7e-27 94.5 0.9 6.8e-27 93.6 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KEY65850.1 - 3.2e-12 45.6 0.9 3.2e-12 45.6 0.6 2.5 3 0 0 3 3 3 1 S4 domain DUF4194 PF13835.1 KEY65850.1 - 0.028 13.8 1.1 0.06 12.7 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4194) Ribosomal_L21e PF01157.13 KEY65851.1 - 2.7e-40 136.1 5.8 4.2e-40 135.5 4.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e DUF3865 PF12981.2 KEY65851.1 - 0.097 12.4 0.1 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) ANTH PF07651.11 KEY65852.1 - 7.1e-78 261.1 0.0 7.1e-78 261.1 0.0 2.5 2 1 0 2 2 2 1 ANTH domain I_LWEQ PF01608.12 KEY65852.1 - 1.4e-63 213.3 8.0 1.4e-63 213.3 5.6 5.2 5 0 0 5 5 5 1 I/LWEQ domain ENTH PF01417.15 KEY65852.1 - 5e-05 23.1 0.0 0.00016 21.5 0.0 2.0 1 0 0 1 1 1 1 ENTH domain MAT_Alpha1 PF04769.7 KEY65853.1 - 1.1e-46 158.7 0.0 1.6e-46 158.2 0.0 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 ATPgrasp_ST PF14397.1 KEY65854.1 - 0.18 10.8 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp HMG_box PF00505.14 KEY65855.1 - 8.6e-21 73.9 2.6 8.6e-21 73.9 1.8 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KEY65855.1 - 6.5e-09 36.0 1.6 1e-08 35.4 1.1 1.2 1 0 0 1 1 1 1 HMG-box domain Exo_endo_phos_2 PF14529.1 KEY65856.1 - 1.5e-21 76.2 0.0 3.6e-21 74.9 0.0 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 KEY65856.1 - 1.5e-16 61.1 0.1 2.3e-16 60.5 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 KEY65856.1 - 3.5e-06 26.8 1.4 8.2e-06 25.6 1.0 1.7 1 0 0 1 1 1 1 GRF zinc finger COX6A PF02046.10 KEY65857.1 - 5.1e-44 148.9 4.1 5.3e-44 148.8 2.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa DUF2933 PF11666.3 KEY65857.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) Apc5 PF12862.2 KEY65858.1 - 5.4e-32 109.4 2.3 5.4e-32 109.4 1.6 3.2 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 5 TPR_1 PF00515.23 KEY65858.1 - 0.0048 16.4 0.9 3.9 7.2 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEY65858.1 - 0.0065 17.1 18.8 0.11 13.1 0.7 5.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 KEY65858.1 - 0.022 14.8 6.3 9.6 6.3 0.1 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KEY65858.1 - 0.035 14.4 11.3 1 9.7 1.2 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEY65858.1 - 0.049 13.4 3.7 1.1 9.1 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat MbeD_MobD PF04899.7 KEY65858.1 - 0.061 13.2 1.5 0.34 10.8 0.0 3.0 3 0 0 3 3 3 0 MbeD/MobD like TPR_4 PF07721.9 KEY65858.1 - 0.11 13.0 10.7 5.3 7.7 0.0 6.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 KEY65858.1 - 0.33 10.6 4.7 8.3 6.1 0.0 4.1 3 1 0 3 3 3 0 TPR repeat TPR_14 PF13428.1 KEY65858.1 - 1.6 9.5 22.4 12 6.9 0.3 7.3 6 3 2 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEY65858.1 - 3.7 7.6 11.5 1.1 9.3 0.1 5.2 7 0 0 7 7 7 0 Tetratricopeptide repeat CIA30 PF08547.7 KEY65859.1 - 1.7e-40 138.4 0.0 2.3e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Tim44 PF04280.10 KEY65860.1 - 2.6e-07 30.7 0.1 5.6e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Tim44-like domain SSF PF00474.12 KEY65861.1 - 9.3e-09 34.4 31.5 7.9e-08 31.3 21.9 2.2 1 1 0 1 1 1 1 Sodium:solute symporter family RRM_1 PF00076.17 KEY65862.1 - 3.8e-22 77.7 0.0 1.1e-09 37.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY65862.1 - 8.4e-15 54.5 0.1 1.8e-09 37.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY65862.1 - 2.2e-12 46.6 0.2 1.4e-06 27.9 0.1 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.2 KEY65863.1 - 2.7e-36 123.7 10.8 3.4e-14 52.9 0.9 4.6 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 KEY65863.1 - 3.6e-27 92.7 17.3 1.9e-06 27.4 0.0 6.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 KEY65863.1 - 2.8e-21 73.4 13.2 0.00016 21.6 0.0 6.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 KEY65863.1 - 4.9e-20 71.4 6.0 5.2e-05 23.6 0.1 5.7 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY65863.1 - 5.6e-15 55.0 11.3 2.1e-06 27.7 0.2 5.3 4 1 2 6 6 6 4 Ankyrin repeats (many copies) F-box-like PF12937.2 KEY65863.1 - 7.9e-05 22.3 0.6 0.00023 20.8 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KEY65863.1 - 0.013 15.1 2.0 0.019 14.5 0.7 1.8 2 0 0 2 2 2 0 F-box domain DUF1857 PF08982.6 KEY65864.1 - 1e-43 148.4 0.0 1.2e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) DUF3875 PF12991.2 KEY65864.1 - 0.091 12.4 0.0 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3875) Ribosomal_S21 PF01165.15 KEY65864.1 - 0.1 12.0 0.2 0.55 9.7 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S21 Dioxygenase_C PF00775.16 KEY65865.1 - 5e-55 185.5 0.0 6.9e-55 185.1 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KEY65865.1 - 8.1e-15 54.5 0.0 4e-14 52.3 0.0 2.2 2 1 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KEY65865.1 - 0.00044 20.2 0.0 0.0014 18.6 0.0 1.8 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain AdoMet_MTase PF07757.8 KEY65866.1 - 2.7e-39 133.7 0.0 6.2e-39 132.5 0.0 1.5 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.1 KEY65866.1 - 0.01 15.5 0.0 2 8.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 KEY65866.1 - 0.037 13.7 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SUI1 PF01253.17 KEY65867.1 - 3.2e-29 100.5 6.1 3.9e-29 100.2 4.2 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cas_Csa5 PF09702.5 KEY65867.1 - 0.14 12.2 0.6 0.3 11.1 0.1 1.7 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csa5) Prim_Zn_Ribbon PF08273.7 KEY65868.1 - 2.6 8.2 7.3 11 6.2 0.8 2.6 2 1 1 3 3 3 0 Zinc-binding domain of primase-helicase SKG6 PF08693.5 KEY65871.1 - 0.0025 17.1 0.1 0.0044 16.3 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Fungal_lectin PF07938.7 KEY65871.1 - 0.016 14.4 0.1 0.23 10.7 0.0 2.6 3 0 0 3 3 3 0 Fungal fucose-specific lectin DUF4229 PF14012.1 KEY65871.1 - 0.046 13.6 0.4 0.088 12.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF2562 PF10814.3 KEY65871.1 - 0.087 12.7 0.4 0.28 11.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2562) Alpha_GJ PF03229.8 KEY65871.1 - 0.37 11.1 6.5 8.5 6.7 2.2 2.4 2 0 0 2 2 2 0 Alphavirus glycoprotein J ATP-sulfurylase PF01747.12 KEY65873.1 - 5.3e-88 293.9 0.0 7.6e-88 293.4 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 KEY65873.1 - 3.7e-52 175.9 0.0 5.6e-52 175.3 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.15 KEY65873.1 - 4.1e-52 175.9 0.0 6.1e-52 175.4 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.5 KEY65873.1 - 0.0072 15.5 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 KEY65873.1 - 0.048 13.5 0.2 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain TRP PF06011.7 KEY65875.1 - 4.1e-91 305.7 20.3 6.6e-91 305.0 14.1 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KEY65875.1 - 2.2e-28 99.0 0.0 3.4e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 ML-like domain UPF0016 PF01169.14 KEY65877.1 - 4.4e-42 142.0 22.9 7.5e-22 77.2 4.4 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 WD40 PF00400.27 KEY65878.1 - 3.7e-24 83.6 12.1 1.7e-08 34.0 0.3 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KEY65878.1 - 0.0021 16.4 1.6 0.051 11.8 0.0 3.3 4 0 0 4 4 4 1 Cytochrome D1 heme domain PQQ_3 PF13570.1 KEY65878.1 - 0.011 15.9 0.0 1.3 9.3 0.0 3.0 2 0 0 2 2 2 0 PQQ-like domain BBS2_Mid PF14783.1 KEY65878.1 - 0.019 14.7 0.1 24 4.7 0.0 3.6 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region CDC45 PF02724.9 KEY65878.1 - 4.6 5.1 6.4 6.4 4.6 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein IBR PF01485.16 KEY65879.1 - 4.2e-11 42.5 56.1 8.7e-08 31.9 3.1 4.7 4 1 0 4 4 4 2 IBR domain zf-C3HC4 PF00097.20 KEY65879.1 - 0.0002 20.9 1.7 0.0002 20.9 1.2 5.1 4 3 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEY65879.1 - 0.0011 18.9 5.1 0.0011 18.9 3.5 4.9 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEY65879.1 - 0.012 15.4 4.9 0.012 15.4 3.4 4.7 5 1 0 5 5 5 0 Ring finger domain RRM_6 PF14259.1 KEY65880.1 - 1e-06 28.5 0.0 1.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEY65880.1 - 0.0035 16.9 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY65880.1 - 0.051 13.4 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.9 KEY65880.1 - 7.2 4.5 6.7 8.6 4.2 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein APH PF01636.18 KEY65881.1 - 1.7e-13 50.8 0.1 3.2e-13 49.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEY65881.1 - 0.001 18.6 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase SET PF00856.23 KEY65882.1 - 8.1e-17 61.9 0.0 1.3e-16 61.3 0.0 1.3 1 0 0 1 1 1 1 SET domain Sec3_C PF09763.4 KEY65884.1 - 1.5e-227 757.2 0.0 1.9e-227 756.7 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 KEY65884.1 - 1.8e-29 101.3 0.0 3.5e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.7 KEY65884.1 - 0.0093 14.5 0.3 0.034 12.6 0.0 1.9 2 0 0 2 2 2 1 Vps52 / Sac2 family Sec3_C_2 PF15278.1 KEY65884.1 - 0.026 14.6 3.0 0.058 13.5 0.0 2.9 3 0 0 3 3 3 0 Sec3 exocyst complex subunit Peptidase_S58 PF03576.9 KEY65885.1 - 1.2e-101 340.2 0.5 1.4e-101 340.0 0.3 1.0 1 0 0 1 1 1 1 Peptidase family S58 DUF1537 PF07005.6 KEY65885.1 - 0.0064 16.1 0.2 0.01 15.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF1537 Fe-ADH PF00465.14 KEY65886.1 - 4.2e-103 344.8 0.0 5.1e-103 344.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KEY65886.1 - 2.1e-16 59.9 0.0 1.5e-13 50.6 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 KEY65886.1 - 0.001 18.5 0.1 0.0017 17.8 0.1 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Virul_Fac PF10139.4 KEY65886.1 - 0.2 9.5 0.0 0.27 9.1 0.0 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor Complex1_51K PF01512.12 KEY65887.1 - 3e-47 160.1 0.0 4.9e-47 159.4 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 KEY65887.1 - 3.4e-18 64.5 0.9 3.4e-18 64.5 0.7 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 KEY65887.1 - 5.4e-09 35.8 0.0 1.3e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 SLBB domain PEX11 PF05648.9 KEY65888.1 - 1e-17 64.2 0.5 2.1e-16 59.8 0.4 2.3 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Smr PF01713.16 KEY65889.1 - 1.5e-09 37.9 0.2 4.3e-09 36.4 0.1 1.9 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 KEY65889.1 - 0.00066 19.1 0.0 0.0015 17.9 0.0 1.7 1 0 0 1 1 1 1 CUE domain DUF1771 PF08590.5 KEY65889.1 - 0.0014 18.5 7.1 0.0038 17.2 5.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) UBA PF00627.26 KEY65889.1 - 0.0026 17.5 0.0 0.017 14.9 0.0 2.4 2 0 0 2 2 2 1 UBA/TS-N domain Patched PF02460.13 KEY65890.1 - 1.3e-75 254.9 3.2 8.2e-45 153.0 0.0 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 KEY65890.1 - 5.7e-49 165.5 3.8 5.7e-49 165.5 2.6 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 KEY65890.1 - 2.6e-09 36.2 30.1 2.4e-05 23.2 6.8 2.4 2 0 0 2 2 2 2 MMPL family DUF4231 PF14015.1 KEY65890.1 - 0.0043 17.0 0.0 0.0043 17.0 0.0 4.2 5 0 0 5 5 5 1 Protein of unknown function (DUF4231) DUF4526 PF15029.1 KEY65890.1 - 0.08 12.5 1.5 0.19 11.2 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4526) Ninjurin PF04923.7 KEY65890.1 - 4.5 7.0 8.9 0.38 10.4 0.0 3.3 3 0 0 3 3 3 0 Ninjurin YTH PF04146.10 KEY65891.1 - 1.5e-37 128.3 0.1 3.3e-37 127.1 0.0 1.6 2 0 0 2 2 2 1 YT521-B-like domain ROKNT PF08067.6 KEY65891.1 - 0.0013 18.5 2.2 1.6 8.6 0.0 3.1 3 0 0 3 3 3 2 ROKNT (NUC014) domain Mannosyl_trans2 PF04188.8 KEY65892.1 - 1.2e-65 222.2 5.5 2.1e-65 221.3 3.8 1.4 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) APH PF01636.18 KEY65893.1 - 8e-17 61.7 0.0 1.1e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Abhydrolase_2 PF02230.11 KEY65894.1 - 6.7e-18 64.9 0.0 2.6e-15 56.4 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KEY65894.1 - 1.6e-05 24.8 0.0 1.9e-05 24.6 0.0 1.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY65894.1 - 1.9e-05 24.4 0.0 3.5e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KEY65894.1 - 0.0022 17.6 0.0 0.0028 17.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEY65894.1 - 0.059 12.5 0.2 1.6 7.8 0.0 2.5 1 1 2 3 3 3 0 Prolyl oligopeptidase family Esterase_phd PF10503.4 KEY65894.1 - 0.12 11.6 0.0 0.23 10.6 0.0 1.5 2 0 0 2 2 2 0 Esterase PHB depolymerase MR_MLE_C PF13378.1 KEY65895.1 - 1.9e-19 69.7 0.0 6.1e-18 64.8 0.0 2.6 3 0 0 3 3 3 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KEY65895.1 - 8.9e-14 51.7 0.0 3e-13 50.0 0.0 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KEY65895.1 - 0.0015 18.5 0.1 0.0085 16.0 0.0 2.1 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF464 PF04327.7 KEY65895.1 - 0.11 12.7 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF464) MAAL_C PF07476.6 KEY65895.1 - 0.14 11.0 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Glyco_transf_21 PF13506.1 KEY65897.1 - 4.8e-05 22.7 0.2 0.25 10.6 0.1 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KEY65897.1 - 0.0014 18.3 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 ADH_N PF08240.7 KEY65899.1 - 2.3e-25 88.4 3.0 3.9e-25 87.7 2.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY65899.1 - 4.7e-17 61.7 0.0 7.8e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KEY65899.1 - 3e-05 23.2 0.3 5.3e-05 22.4 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 KEY65899.1 - 0.083 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA WD40 PF00400.27 KEY65900.1 - 1.4e-05 24.8 8.3 0.042 13.7 0.1 6.1 7 0 0 7 7 7 1 WD domain, G-beta repeat eIF2A PF08662.6 KEY65900.1 - 0.00055 19.7 0.2 0.15 11.7 0.0 3.3 4 0 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KEY65900.1 - 0.033 13.8 0.3 1.9e+02 1.8 0.0 4.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat ERM PF00769.14 KEY65901.1 - 0.0024 17.4 35.4 0.004 16.7 24.5 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF1183 PF06682.7 KEY65901.1 - 0.051 13.1 0.3 0.051 13.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) DUF1777 PF08648.7 KEY65901.1 - 7.3 6.2 34.3 15 5.2 23.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) PX PF00787.19 KEY65902.1 - 1.5e-12 47.3 0.0 2.4e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 KEY65902.1 - 4.9e-11 42.1 4.9 9.5e-11 41.2 3.4 1.5 1 0 0 1 1 1 1 SNARE domain EB1 PF03271.12 KEY65903.1 - 2.4e-17 62.6 1.5 4.9e-17 61.6 1.0 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 KEY65903.1 - 1.5e-07 31.4 0.7 2.6e-07 30.6 0.5 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Syja_N PF02383.13 KEY65903.1 - 0.025 13.3 0.0 0.025 13.3 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain Suppressor_APC PF11414.3 KEY65903.1 - 0.12 12.2 0.6 0.26 11.0 0.4 1.6 1 1 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein DEAD PF00270.24 KEY65904.1 - 5.8e-43 146.3 0.1 1.1e-42 145.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2183 PF09949.4 KEY65904.1 - 1.8e-32 111.2 0.0 5.4e-32 109.7 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Helicase_C PF00271.26 KEY65904.1 - 3.2e-25 87.7 0.0 7e-25 86.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KEY65904.1 - 0.0003 19.3 2.5 0.00044 18.7 0.1 2.3 2 1 1 3 3 3 1 Protein of unknown function (DUF1253) AMP-binding PF00501.23 KEY65905.1 - 1e-58 198.7 0.6 1.9e-23 82.5 0.0 4.7 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.6 KEY65905.1 - 0.0021 18.6 0.1 0.0046 17.5 0.1 1.5 1 0 0 1 1 1 1 DMAP1-binding Domain PDEase_II PF02112.10 KEY65908.1 - 4e-56 190.3 0.0 1.4e-24 86.6 0.0 3.1 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B PF00753.22 KEY65908.1 - 0.0045 16.6 0.8 0.021 14.4 0.6 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KEY65908.1 - 0.016 14.7 0.1 0.073 12.6 0.0 2.2 2 1 0 2 2 2 0 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 KEY65909.1 - 7.8e-29 100.6 0.0 1.7e-28 99.5 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 KEY65909.1 - 7.4e-16 57.3 0.0 2.3e-15 55.7 0.0 1.9 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 KEY65909.1 - 1.6e-11 44.2 0.1 4.2e-11 42.8 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily YCII PF03795.9 KEY65909.1 - 0.053 13.7 0.0 0.2 11.8 0.0 2.0 1 0 0 1 1 1 0 YCII-related domain MIP-T3 PF10243.4 KEY65910.1 - 0.22 9.9 0.7 0.29 9.5 0.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Pkinase PF00069.20 KEY65911.1 - 2.5e-61 207.1 0.0 3.5e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY65911.1 - 2.1e-19 69.6 0.0 6.8e-19 67.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY65911.1 - 0.015 14.2 0.3 4.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.6 KEY65911.1 - 0.1 11.3 0.1 0.16 10.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Mtc PF03820.12 KEY65913.1 - 5.2e-94 314.3 0.2 3.5e-93 311.6 0.2 1.9 1 1 0 1 1 1 1 Tricarboxylate carrier PNPase_C PF12111.3 KEY65913.1 - 1.6 7.9 4.1 4.2 6.6 2.8 1.6 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal Arf PF00025.16 KEY65915.1 - 2.8e-67 225.3 0.4 3.1e-67 225.1 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KEY65915.1 - 1.9e-12 46.6 0.8 5e-07 28.7 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KEY65915.1 - 7.7e-12 44.8 0.0 9e-12 44.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KEY65915.1 - 2.2e-09 36.8 0.0 2.5e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KEY65915.1 - 3.6e-09 37.1 0.0 4.8e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KEY65915.1 - 5.6e-09 35.9 0.0 8.2e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KEY65915.1 - 2.6e-08 33.3 0.0 3e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KEY65915.1 - 0.00012 21.5 0.0 0.015 14.7 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 KEY65915.1 - 0.051 13.0 0.1 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 KEY65915.1 - 0.052 12.8 0.1 0.14 11.4 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_17 PF13207.1 KEY65915.1 - 0.056 14.2 0.2 0.1 13.4 0.1 1.4 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.13 KEY65915.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase NACHT PF05729.7 KEY65915.1 - 0.14 11.8 0.3 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 NACHT domain DUF4045 PF13254.1 KEY65916.1 - 5e-82 276.4 41.3 1.5e-43 149.6 19.9 6.2 4 2 2 6 6 6 2 Domain of unknown function (DUF4045) Gelsolin PF00626.17 KEY65916.1 - 2.6e-12 46.2 0.0 0.0027 17.3 0.0 3.9 3 0 0 3 3 3 3 Gelsolin repeat Acyltransferase PF01553.16 KEY65917.1 - 6.7e-34 116.1 0.0 9.7e-34 115.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF2347 PF09804.4 KEY65918.1 - 6.4e-104 347.1 0.0 8.7e-104 346.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 KEY65918.1 - 2.2e-48 164.6 0.0 4.7e-48 163.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.5 KEY65918.1 - 3e-08 33.3 0.0 5.5e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KEY65918.1 - 0.00024 19.7 0.0 0.001 17.6 0.0 2.0 2 0 0 2 2 2 1 Transport protein Avl9 DUF2001 PF09393.5 KEY65918.1 - 0.086 12.5 0.1 4.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2001) NAGidase PF07555.8 KEY65918.1 - 0.095 11.5 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase Sec63 PF02889.11 KEY65919.1 - 1.7e-46 158.8 0.0 3.3e-46 157.9 0.0 1.4 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 KEY65919.1 - 4.7e-17 61.4 0.3 9.8e-17 60.4 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain DUF3336 PF11815.3 KEY65920.1 - 2.1e-51 173.2 9.6 3.1e-51 172.7 6.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KEY65920.1 - 1.1e-20 74.5 0.1 2.6e-20 73.2 0.1 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase CHAD PF05235.9 KEY65920.1 - 0.0027 17.3 0.2 0.005 16.4 0.1 1.4 1 0 0 1 1 1 1 CHAD domain Hph PF13694.1 KEY65920.1 - 0.037 14.0 0.2 0.071 13.1 0.1 1.4 1 0 0 1 1 1 0 Sec63/Sec62 complex-interacting family Arf PF00025.16 KEY65921.1 - 7.4e-66 220.6 0.0 8.2e-66 220.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KEY65921.1 - 1.4e-09 37.1 0.2 6.3e-06 25.1 0.0 2.3 1 1 0 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KEY65921.1 - 8.6e-08 32.7 0.0 1.2e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KEY65921.1 - 1.6e-07 30.8 0.0 2.3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KEY65921.1 - 3.6e-07 29.5 0.0 4.8e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KEY65921.1 - 5.3e-07 29.5 0.0 7.1e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KEY65921.1 - 4.7e-05 22.6 0.0 5.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KEY65921.1 - 0.0068 15.8 0.1 0.31 10.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 KEY65921.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF2457 PF10446.4 KEY65922.1 - 1.8e-123 412.7 23.4 1.8e-123 412.7 16.2 2.3 2 1 1 3 3 3 1 Protein of unknown function (DUF2457) ATP-synt_DE_N PF02823.11 KEY65923.1 - 2.7e-18 65.4 0.0 4.3e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Vps39_2 PF10367.4 KEY65926.1 - 1.1e-06 28.7 0.0 3e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 KEY65926.1 - 0.04 13.9 0.0 0.15 12.1 0.0 2.0 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.15 KEY65926.1 - 0.054 13.0 0.0 4.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Region in Clathrin and VPS CASP_C PF08172.7 KEY65927.1 - 1.3e-90 302.8 0.0 1.3e-90 302.8 0.0 3.5 2 1 1 3 3 3 1 CASP C terminal HALZ PF02183.13 KEY65927.1 - 0.018 14.7 2.1 0.018 14.7 1.4 6.0 6 1 0 6 6 6 0 Homeobox associated leucine zipper Filament PF00038.16 KEY65927.1 - 0.091 12.2 49.6 0.29 10.5 3.0 4.2 2 1 1 4 4 4 0 Intermediate filament protein NAD_binding_1 PF00175.16 KEY65927.1 - 0.48 11.0 2.4 3.9 8.0 0.0 3.0 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain SlyX PF04102.7 KEY65927.1 - 0.71 10.2 0.0 0.71 10.2 0.0 6.1 6 1 0 6 6 6 0 SlyX Reo_sigmaC PF04582.7 KEY65927.1 - 3.4 6.7 23.0 0.28 10.3 4.4 4.3 2 1 1 4 4 4 0 Reovirus sigma C capsid protein Mnd1 PF03962.10 KEY65927.1 - 4.2 6.9 43.3 0.013 15.1 2.6 5.0 4 1 0 5 5 5 0 Mnd1 family Tropomyosin_1 PF12718.2 KEY65927.1 - 7.4 6.4 54.4 2.2 8.1 3.9 5.5 4 1 1 5 5 5 0 Tropomyosin like DUF3455 PF11937.3 KEY65928.1 - 1.5e-40 139.0 0.1 2e-40 138.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) F-box PF00646.28 KEY65929.1 - 0.00095 18.7 0.0 0.0036 16.9 0.0 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KEY65929.1 - 0.052 13.2 0.0 0.16 11.6 0.0 1.9 1 0 0 1 1 1 0 F-box-like Ribosomal_L22 PF00237.14 KEY65930.1 - 1.3e-33 115.0 0.1 1.8e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Fibrillarin PF01269.12 KEY65931.1 - 5.6e-101 336.2 0.0 6.8e-101 335.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 KEY65931.1 - 8.9e-05 22.0 0.0 0.0002 20.9 0.0 1.5 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 KEY65931.1 - 0.037 13.5 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) p450 PF00067.17 KEY65932.1 - 9.2e-39 133.2 0.0 1.2e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 KEY65933.1 - 2.1e-42 145.0 0.0 3e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KEY65933.1 - 5.2e-10 39.8 0.0 1.1e-09 38.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Nitroreductase PF00881.19 KEY65934.1 - 3.5e-11 43.1 0.0 4.3e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family PS_Dcarbxylase PF02666.10 KEY65935.1 - 1.3e-83 279.2 0.0 2e-82 275.3 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase ubiquitin PF00240.18 KEY65936.1 - 2.8e-06 26.6 0.0 7.5e-06 25.2 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KEY65936.1 - 6.5e-06 26.2 0.3 2.5e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 KEY65936.1 - 0.0064 16.3 0.0 0.019 14.8 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Peptidase_C12 PF01088.16 KEY65937.1 - 4e-70 235.3 0.0 5.3e-70 234.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Xan_ur_permease PF00860.15 KEY65938.1 - 3.7e-26 91.5 30.0 1.8e-25 89.2 20.3 2.4 1 1 0 1 1 1 1 Permease family Methyltransf_12 PF08242.7 KEY65939.1 - 0.0052 17.2 0.0 0.41 11.1 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY65939.1 - 0.0053 17.2 0.0 0.02 15.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Dicty_CAR PF05462.6 KEY65940.1 - 1.3e-08 34.1 7.3 1.3e-08 34.1 5.1 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 KEY65940.1 - 9.1e-08 31.9 8.6 1.9e-07 30.8 6.0 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KEY65940.1 - 7e-06 25.3 4.7 1e-05 24.8 3.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KEY65940.1 - 0.0065 15.6 3.3 0.01 15.0 2.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx T2SF PF00482.18 KEY65942.1 - 0.23 11.3 0.5 1.2 9.0 0.1 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F IncA PF04156.9 KEY65942.1 - 0.31 10.6 5.3 0.12 12.0 0.6 2.2 2 0 0 2 2 2 0 IncA protein adh_short PF00106.20 KEY65944.1 - 5.4e-26 91.4 2.3 7.8e-26 90.9 1.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY65944.1 - 8.3e-25 87.9 0.0 1.1e-24 87.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY65944.1 - 8e-12 45.1 0.7 1.3e-11 44.5 0.5 1.2 1 0 0 1 1 1 1 KR domain N2227 PF07942.7 KEY65945.1 - 2.7e-99 331.5 0.0 3.3e-99 331.2 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 KEY65945.1 - 7.8e-06 25.7 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY65945.1 - 0.0023 18.3 0.1 0.013 15.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY65945.1 - 0.05 14.0 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KEY65945.1 - 0.057 14.0 0.0 0.21 12.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain HEAT_EZ PF13513.1 KEY65947.1 - 2.3e-27 94.7 16.3 2.6e-13 50.0 0.0 11.3 9 2 2 11 11 11 5 HEAT-like repeat HEAT PF02985.17 KEY65947.1 - 1.2e-26 90.3 10.0 0.00027 20.7 0.0 10.2 10 0 0 10 10 10 5 HEAT repeat HEAT_2 PF13646.1 KEY65947.1 - 1.9e-21 76.1 4.4 1.7e-07 31.4 0.0 7.7 3 3 7 10 10 10 6 HEAT repeats Vac14_Fab1_bd PF12755.2 KEY65947.1 - 5.3e-09 36.3 0.0 0.009 16.3 0.0 6.3 7 1 0 7 7 7 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 KEY65947.1 - 3.8e-08 32.4 0.5 0.25 10.0 0.0 4.9 5 0 0 5 5 5 2 RNAPII transcription regulator C-terminal IBN_N PF03810.14 KEY65947.1 - 5.6e-08 32.5 1.8 5.2e-05 23.0 0.1 4.7 3 1 1 4 4 4 1 Importin-beta N-terminal domain Cnd1 PF12717.2 KEY65947.1 - 4e-06 26.7 0.6 4.3 7.1 0.0 5.8 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KEY65947.1 - 4.2e-06 26.2 0.1 7.9 5.7 0.0 6.7 6 2 2 8 8 8 1 CLASP N terminal Arm PF00514.18 KEY65947.1 - 0.00015 21.4 3.9 0.27 11.1 0.0 6.1 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 KEY65947.1 - 0.13 12.8 10.5 1 10.0 0.0 6.1 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat Zn_clus PF00172.13 KEY65949.1 - 1.9e-07 30.8 12.1 2.9e-07 30.3 8.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEY65949.1 - 4e-06 25.6 1.6 4.7e-06 25.4 0.5 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain FliG_M PF14841.1 KEY65949.1 - 0.04 13.9 0.1 0.078 12.9 0.1 1.4 1 0 0 1 1 1 0 FliG middle domain SPRY PF00622.23 KEY65950.1 - 4.1e-18 65.6 0.0 6.6e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 SPRY domain CBFB_NFYA PF02045.10 KEY65952.1 - 2e-30 105.0 4.8 3.8e-30 104.1 3.3 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.7 KEY65952.1 - 0.083 11.8 0.1 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Hus1-like protein TPR_10 PF13374.1 KEY65953.1 - 4e-99 322.1 0.0 2.5e-13 49.4 0.0 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.1 KEY65953.1 - 1.5e-83 274.7 0.0 2.7e-19 68.8 0.0 6.3 3 1 2 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 KEY65953.1 - 9.7e-25 84.3 15.1 0.0032 17.1 0.0 8.5 10 0 0 10 10 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 KEY65953.1 - 2.9e-24 83.2 1.6 0.072 13.3 0.0 8.6 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_4 PF07721.9 KEY65953.1 - 1.3e-22 77.8 0.2 0.71 10.4 0.0 9.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 KEY65953.1 - 2.9e-22 78.0 1.7 6e-06 25.8 0.0 6.8 3 2 4 7 7 7 6 TPR repeat TPR_1 PF00515.23 KEY65953.1 - 2.6e-20 71.0 0.9 0.14 11.8 0.0 8.0 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 KEY65953.1 - 1.2e-19 68.5 8.2 0.4 10.7 0.0 8.9 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 KEY65953.1 - 2.5e-16 59.8 0.0 0.015 15.9 0.0 7.3 1 1 7 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 KEY65953.1 - 1.2e-15 56.0 5.0 0.58 10.0 0.0 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 KEY65953.1 - 5.7e-13 48.2 6.3 0.76 10.5 0.0 9.0 6 3 3 9 9 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEY65953.1 - 3e-12 46.6 0.0 0.02 15.1 0.0 7.5 3 1 5 8 8 8 2 Tetratricopeptide repeat NB-ARC PF00931.17 KEY65953.1 - 2.5e-10 39.6 0.0 5.2e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain PPR PF01535.15 KEY65953.1 - 9.3e-09 34.6 4.1 1.4 9.0 0.0 7.5 8 0 0 8 8 8 2 PPR repeat Apc3 PF12895.2 KEY65953.1 - 6.5e-08 32.5 0.0 0.079 13.1 0.0 4.7 1 1 4 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KEY65953.1 - 1.6e-06 28.1 10.5 1.3 9.6 0.0 7.5 8 0 0 8 8 6 1 Tetratricopeptide repeat NACHT PF05729.7 KEY65953.1 - 2.1e-05 24.2 0.0 4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PPR_2 PF13041.1 KEY65953.1 - 0.00018 21.4 0.0 5.3 7.1 0.1 5.2 5 1 1 6 6 5 1 PPR repeat family TPR_3 PF07720.7 KEY65953.1 - 0.00029 20.5 0.0 0.77 9.6 0.0 4.8 6 0 0 6 6 5 1 Tetratricopeptide repeat DUF1481 PF07356.7 KEY65953.1 - 0.00031 20.2 2.1 2.9 7.3 0.0 5.0 1 1 5 6 6 6 1 Protein of unknown function (DUF1481) AAA_16 PF13191.1 KEY65953.1 - 0.0099 15.8 0.0 0.032 14.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain PPR_3 PF13812.1 KEY65953.1 - 0.021 15.0 5.1 9.7 6.7 0.1 6.0 8 0 0 8 8 4 0 Pentatricopeptide repeat domain DUF1897 PF09005.5 KEY65953.1 - 0.052 13.0 5.9 6.1 6.3 0.0 5.6 7 0 0 7 7 6 0 Domain of unknown function (DUF1897) AAA_22 PF13401.1 KEY65953.1 - 0.093 12.8 0.0 0.32 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KEY65953.1 - 0.13 11.9 0.0 0.35 10.5 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase PGAP1 PF07819.8 KEY65954.1 - 0.023 14.2 0.0 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein PNP_UDP_1 PF01048.15 KEY65955.1 - 2e-17 62.9 1.8 1.4e-16 60.1 1.3 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily DUF2274 PF10038.4 KEY65955.1 - 0.017 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2274) DUF3419 PF11899.3 KEY65956.1 - 0.023 13.4 0.0 0.024 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) APH PF01636.18 KEY65957.1 - 5.5e-43 147.4 0.0 7.7e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KEY65957.1 - 4.9e-07 29.1 0.1 3e-06 26.5 0.1 2.0 1 1 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.9 KEY65957.1 - 0.0001 21.3 0.0 0.00029 19.9 0.0 1.7 1 1 0 1 1 1 1 Fructosamine kinase RIO1 PF01163.17 KEY65957.1 - 0.01 15.2 0.0 0.48 9.7 0.0 2.3 2 0 0 2 2 2 0 RIO1 family DUF1679 PF07914.6 KEY65957.1 - 0.05 12.2 0.0 0.18 10.4 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) PspC PF04024.7 KEY65957.1 - 0.13 11.7 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 PspC domain Methyltransf_26 PF13659.1 KEY65958.1 - 1.9e-14 53.6 0.1 5.3e-14 52.2 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY65958.1 - 0.017 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain LSM PF01423.17 KEY65959.1 - 3.2e-16 58.6 0.1 4.2e-16 58.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KEY65959.1 - 0.00011 22.0 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain API5 PF05918.6 KEY65959.1 - 7.2 4.9 6.8 8.7 4.7 4.7 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Cullin PF00888.17 KEY65960.1 - 1.3e-129 433.4 1.5 1.7e-129 433.0 1.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KEY65960.1 - 1.9e-28 98.0 3.0 2e-28 98.0 0.8 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain FAA_hydrolase PF01557.13 KEY65961.1 - 1.1e-52 178.6 0.0 1.3e-52 178.3 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 3-HAO PF06052.7 KEY65962.1 - 2.2e-62 208.9 0.0 2.7e-62 208.6 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 KEY65962.1 - 2.3e-06 27.0 0.0 3.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KEY65962.1 - 0.00038 19.9 0.0 0.00062 19.2 0.0 1.3 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 KEY65962.1 - 0.0021 17.7 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain DZR PF12773.2 KEY65962.1 - 0.0056 16.4 3.0 0.011 15.5 2.1 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-HC5HC2H_2 PF13832.1 KEY65962.1 - 0.012 15.6 0.2 0.02 14.9 0.1 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain Cupin_4 PF08007.7 KEY65962.1 - 0.044 13.0 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein Nudix_N_2 PF14803.1 KEY65962.1 - 0.1 12.3 1.1 3.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Nudix N-terminal ARD PF03079.9 KEY65962.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family C1_1 PF00130.17 KEY65962.1 - 0.21 11.3 1.8 3.8 7.3 0.2 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ctr PF04145.10 KEY65963.1 - 3.1e-33 114.8 17.0 3.2e-32 111.5 11.8 1.9 1 1 0 1 1 1 1 Ctr copper transporter family NDUF_B5 PF09781.4 KEY65963.1 - 0.049 12.8 0.4 0.062 12.5 0.3 1.1 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit NUDIX PF00293.23 KEY65964.1 - 1.7e-13 50.3 0.0 2.7e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain SF3b1 PF08920.5 KEY65965.1 - 5.3e-33 114.1 9.3 1.2e-31 109.7 6.5 2.4 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 KEY65965.1 - 2.1e-15 56.7 3.2 0.01 16.1 0.0 7.3 6 2 2 8 8 8 5 HEAT repeats HEAT_EZ PF13513.1 KEY65965.1 - 8.2e-13 48.4 1.0 0.34 11.4 0.0 8.7 7 2 2 9 9 9 2 HEAT-like repeat HEAT PF02985.17 KEY65965.1 - 5.8e-12 44.6 8.3 1 9.6 0.0 9.7 10 0 0 10 10 10 3 HEAT repeat Vac14_Fab1_bd PF12755.2 KEY65965.1 - 7e-06 26.3 0.1 0.49 10.8 0.0 5.5 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KEY65965.1 - 9.3e-05 20.9 1.0 0.028 12.7 0.1 3.3 2 2 0 3 3 3 2 Adaptin N terminal region UPF0236 PF06782.6 KEY65965.1 - 0.00042 18.8 0.1 0.0007 18.1 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0236) NUC173 PF08161.7 KEY65965.1 - 0.0078 15.5 0.1 4.9 6.4 0.0 3.7 3 0 0 3 3 3 1 NUC173 domain CLASP_N PF12348.3 KEY65965.1 - 0.011 15.1 0.3 1.3 8.3 0.0 3.7 4 0 0 4 4 4 0 CLASP N terminal Cnd1 PF12717.2 KEY65965.1 - 0.026 14.3 0.8 35 4.1 0.0 4.4 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 zf-H2C2_2 PF13465.1 KEY65966.1 - 1.9e-10 40.4 13.0 1.2e-05 25.3 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KEY65966.1 - 3.8e-08 33.2 18.8 1.9e-05 24.7 3.1 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY65966.1 - 3.6e-07 30.0 9.4 0.00019 21.5 1.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KEY65966.1 - 6.6e-06 26.1 1.5 1.9e-05 24.7 1.0 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KEY65966.1 - 6.9e-05 22.8 5.1 0.00011 22.1 1.4 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KEY65966.1 - 0.00022 21.0 6.2 0.0038 17.0 1.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KEY65966.1 - 0.042 13.9 1.1 0.042 13.9 0.8 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 KEY65966.1 - 1.6 9.1 9.0 4.6 7.6 0.9 3.6 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-BED PF02892.10 KEY65966.1 - 2.1 8.1 5.9 0.92 9.3 1.1 2.2 1 1 1 2 2 2 0 BED zinc finger Rax2 PF12768.2 KEY65969.1 - 5.2e-94 314.5 0.6 4.3e-83 278.7 0.0 5.2 4 2 2 6 6 6 5 Cortical protein marker for cell polarity DUF1668 PF07893.8 KEY65969.1 - 0.003 16.7 0.0 0.64 9.0 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1668) Kelch_6 PF13964.1 KEY65969.1 - 0.005 16.9 1.6 2.4 8.4 0.0 5.0 5 0 0 5 5 5 1 Kelch motif SNase PF00565.12 KEY65970.1 - 1.8e-25 89.2 0.0 2.7e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue P34-Arc PF04045.9 KEY65971.1 - 1.7e-99 332.0 0.5 2e-99 331.7 0.3 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc WD40 PF00400.27 KEY65972.1 - 7.6e-71 231.6 19.6 1e-08 34.6 0.0 12.5 13 0 0 13 13 13 10 WD domain, G-beta repeat Utp12 PF04003.7 KEY65972.1 - 6.9e-21 74.2 0.7 1.1e-20 73.5 0.5 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 KEY65972.1 - 0.00014 20.1 3.0 0.38 8.8 0.1 4.7 4 2 0 5 5 5 2 Nucleoporin Nup120/160 eIF2A PF08662.6 KEY65972.1 - 0.0044 16.7 0.7 1.3 8.7 0.0 4.2 5 1 1 6 6 6 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KEY65972.1 - 0.0096 14.7 3.7 3.2 6.4 0.1 4.1 2 1 1 4 4 4 2 Nup133 N terminal like LSM PF01423.17 KEY65973.1 - 3.1e-16 58.6 0.7 4.4e-16 58.1 0.5 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KEY65973.1 - 0.005 16.7 0.1 0.0072 16.2 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Glutaredoxin2_C PF04399.8 KEY65973.1 - 0.06 12.9 0.1 0.074 12.6 0.1 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Gemin7 PF11095.3 KEY65973.1 - 0.087 12.5 0.0 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 Gem-associated protein 7 (Gemin7) HTH_25 PF13413.1 KEY65973.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DRMBL PF07522.9 KEY65974.1 - 1.9e-33 114.7 0.0 3.5e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KEY65974.1 - 2.1e-12 46.9 0.0 6.1e-12 45.4 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Pkinase PF00069.20 KEY65976.1 - 6.5e-58 195.9 0.0 8.6e-58 195.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY65976.1 - 2.8e-43 147.8 0.0 3.9e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEY65976.1 - 0.0024 17.6 0.0 0.0089 15.7 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEY65976.1 - 0.0031 16.5 0.0 0.011 14.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KEY65976.1 - 0.045 12.7 0.0 0.088 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Telomere_reg-2 PF10193.4 KEY65977.1 - 3.5e-36 123.9 0.0 7.7e-36 122.8 0.0 1.6 1 0 0 1 1 1 1 Telomere length regulation protein ThiF PF00899.16 KEY65978.1 - 3.8e-38 130.3 0.5 1.2e-37 128.7 0.1 1.8 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 KEY65978.1 - 6.7e-31 105.8 0.4 1.4e-30 104.8 0.0 1.7 2 0 0 2 2 2 1 E2 binding domain UBACT PF02134.16 KEY65978.1 - 6.4e-25 86.5 0.3 1.3e-24 85.5 0.2 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KEY65978.1 - 1.7e-14 52.9 1.9 1.7e-14 52.9 1.3 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 KEY65978.1 - 3.2e-05 23.9 0.0 0.00045 20.2 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_9 PF13454.1 KEY65978.1 - 0.025 14.3 0.4 0.12 12.1 0.1 2.1 1 1 1 2 2 2 0 FAD-NAD(P)-binding UBA_e1_C PF09358.5 KEY65978.1 - 0.037 14.1 0.0 0.09 12.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain Shikimate_DH PF01488.15 KEY65978.1 - 0.056 13.5 0.1 0.32 11.1 0.0 1.9 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 KEY65978.1 - 0.085 12.4 0.1 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 MoeZ/MoeB domain RNA_pol_A_bac PF01000.21 KEY65979.1 - 9.3e-27 93.4 0.0 1.7e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KEY65979.1 - 4.4e-14 51.3 0.0 5.7e-14 50.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain WD40 PF00400.27 KEY65980.1 - 0.065 13.1 0.2 0.18 11.7 0.2 1.8 1 0 0 1 1 1 0 WD domain, G-beta repeat Proteasome PF00227.21 KEY65981.1 - 1e-45 155.3 0.0 1.3e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 KEY65981.1 - 4.4e-12 45.0 0.4 1e-11 43.8 0.3 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Sel1 PF08238.7 KEY65982.1 - 4.3e-13 49.4 13.1 0.0015 19.0 0.8 4.4 4 0 0 4 4 4 3 Sel1 repeat COPIIcoated_ERV PF07970.7 KEY65983.1 - 1.1e-70 237.7 0.0 5.1e-47 160.3 0.0 2.3 1 1 0 2 2 2 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KEY65983.1 - 9.6e-34 115.2 0.0 1.9e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Binary_toxB PF03495.9 KEY65984.1 - 0.083 11.4 0.4 0.1 11.2 0.3 1.0 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA CSTF2_hinge PF14327.1 KEY65985.1 - 1.2e-30 105.4 0.4 2.5e-30 104.3 0.3 1.6 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 KEY65985.1 - 2.5e-20 71.8 0.0 3.8e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY65985.1 - 2.3e-17 62.7 0.0 5.4e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 KEY65985.1 - 3.3e-08 32.6 8.0 3.3e-08 32.6 5.5 2.8 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 KEY65985.1 - 1.1e-07 31.6 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 KEY65985.1 - 0.069 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Sporulation protein family 7 CorA PF01544.13 KEY65986.1 - 3.1e-39 134.7 1.6 1.8e-38 132.2 1.1 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Guanylate_kin PF00625.16 KEY65986.1 - 0.19 11.1 0.4 0.37 10.2 0.3 1.4 1 0 0 1 1 1 0 Guanylate kinase CBF PF03914.12 KEY65987.1 - 4.9e-45 152.9 0.6 2e-44 150.9 0.0 2.2 3 0 0 3 3 3 1 CBF/Mak21 family Utp12 PF04003.7 KEY65987.1 - 0.11 12.4 0.8 0.93 9.4 0.4 2.4 2 0 0 2 2 2 0 Dip2/Utp12 Family Mt_ATP-synt_B PF05405.9 KEY65988.1 - 1.2e-54 184.2 6.7 1.4e-54 183.9 4.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Orthopox_A5L PF06193.6 KEY65988.1 - 0.031 14.1 0.4 0.082 12.8 0.2 1.6 1 1 0 1 1 1 0 Orthopoxvirus A5L protein-like DivIC PF04977.10 KEY65988.1 - 1.8 8.1 9.0 0.77 9.2 0.4 3.2 3 0 0 3 3 3 0 Septum formation initiator MSC PF09402.5 KEY65989.1 - 2.3e-100 335.5 0.0 3.1e-100 335.1 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 KEY65989.1 - 2.1e-13 49.5 0.0 4.8e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 HeH/LEM domain DUF3350 PF11830.3 KEY65989.1 - 0.025 14.6 4.6 0.62 10.1 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3350) DUF2630 PF10944.3 KEY65989.1 - 0.24 11.5 3.2 5 7.3 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) FAD_binding_3 PF01494.14 KEY65990.1 - 4.3e-24 85.2 0.2 1.2e-22 80.4 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEY65990.1 - 1.7e-05 23.8 0.3 0.1 11.4 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.5 KEY65990.1 - 0.00026 19.9 0.0 0.0004 19.3 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.7 KEY65990.1 - 0.00032 19.7 1.0 0.012 14.5 0.1 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein Trp_halogenase PF04820.9 KEY65990.1 - 0.0059 15.2 0.0 2.1 6.8 0.0 3.1 2 1 0 3 3 3 1 Tryptophan halogenase NAD_binding_9 PF13454.1 KEY65990.1 - 0.012 15.3 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KEY65990.1 - 0.021 14.7 0.0 0.041 13.7 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEY65990.1 - 0.023 13.7 0.0 0.88 8.6 0.0 2.1 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.1 KEY65990.1 - 0.024 13.5 0.0 0.044 12.6 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KEY65990.1 - 0.037 14.0 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Complex1_49kDa PF00346.14 KEY65991.1 - 2.3e-134 446.6 0.0 3e-134 446.2 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Zn_clus PF00172.13 KEY65992.1 - 0.026 14.4 2.9 0.042 13.7 2.0 1.2 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KEY65993.1 - 1.2e-28 100.0 0.0 4.4e-28 98.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY65993.1 - 4.8e-09 35.6 0.0 0.0009 18.3 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KEY65993.1 - 0.085 12.5 0.0 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Metallopep PF12044.3 KEY65994.1 - 4.2e-132 440.6 0.0 5e-132 440.3 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_4 PF13583.1 KEY65994.1 - 0.015 14.8 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KEY65994.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KEY65994.1 - 0.02 15.4 0.1 0.092 13.2 0.1 2.1 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KEY65994.1 - 0.042 13.7 0.1 0.082 12.8 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 OTT_1508_deam PF14441.1 KEY65996.1 - 2.7e-15 56.4 0.1 5.2e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase AAA_10 PF12846.2 KEY65996.1 - 0.028 13.8 0.0 5.7 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain DUF3638 PF12340.3 KEY65997.1 - 2e-92 308.3 1.2 5e-92 307.0 0.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 KEY65997.1 - 4.5e-16 57.6 0.4 1.2e-15 56.2 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) ABC2_membrane PF01061.19 KEY65998.1 - 4.4e-84 280.8 54.6 5.7e-45 153.0 13.2 3.5 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 KEY65998.1 - 5e-38 128.9 4.2 8.4e-32 108.9 0.0 2.6 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 KEY65998.1 - 1.1e-31 109.9 0.2 2.6e-15 56.9 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KEY65998.1 - 1.8e-13 50.2 39.5 2e-09 36.9 10.4 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 KEY65998.1 - 2.4e-09 37.1 0.6 7e-09 35.6 0.0 2.2 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KEY65998.1 - 6.4e-07 28.9 1.7 0.00095 18.6 0.0 3.0 4 0 0 4 4 3 2 AAA domain AAA_17 PF13207.1 KEY65998.1 - 3.5e-06 27.8 0.0 0.00026 21.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KEY65998.1 - 3.5e-06 26.5 0.0 0.00067 19.1 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 KEY65998.1 - 3.6e-06 27.0 2.2 0.0017 18.3 0.1 3.5 3 0 0 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 KEY65998.1 - 1.3e-05 24.4 0.0 2.9e-05 23.3 0.0 1.5 2 0 0 2 2 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEY65998.1 - 4.1e-05 23.7 0.0 0.042 13.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.1 KEY65998.1 - 5.6e-05 23.2 0.0 0.03 14.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEY65998.1 - 0.00014 21.2 0.0 0.003 17.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain UPF0079 PF02367.12 KEY65998.1 - 0.0002 20.9 0.3 0.054 13.1 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 KEY65998.1 - 0.00045 20.1 3.6 0.016 15.0 0.0 3.2 4 0 0 4 4 2 1 AAA domain AAA_19 PF13245.1 KEY65998.1 - 0.001 18.7 0.1 0.38 10.5 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 KEY65998.1 - 0.0018 17.9 0.4 0.21 11.2 0.1 3.0 3 0 0 3 3 3 1 NACHT domain T2SE PF00437.15 KEY65998.1 - 0.0025 16.7 0.0 0.45 9.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_28 PF13521.1 KEY65998.1 - 0.0026 17.7 0.1 0.0026 17.7 0.0 2.7 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.1 KEY65998.1 - 0.0028 17.9 0.0 0.02 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KEY65998.1 - 0.0031 17.6 0.2 0.91 9.7 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KEY65998.1 - 0.016 15.5 3.4 0.038 14.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 KEY65998.1 - 0.021 14.7 0.3 0.64 9.9 0.0 2.8 3 0 0 3 3 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KEY65998.1 - 0.047 13.1 0.0 2.4 7.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 KEY65998.1 - 0.051 13.1 0.1 0.92 9.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KEY65998.1 - 0.11 12.9 0.0 5.9 7.4 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Arch_ATPase PF01637.13 KEY65998.1 - 0.12 12.0 0.0 7 6.2 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase AAA_10 PF12846.2 KEY65998.1 - 0.2 11.0 0.8 3.9 6.8 0.2 2.7 3 0 0 3 3 3 0 AAA-like domain PduV-EutP PF10662.4 KEY65998.1 - 0.28 10.6 0.5 0.86 9.0 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Vpu PF00558.14 KEY65998.1 - 0.44 10.1 2.8 0.47 10.0 0.1 2.4 2 0 0 2 2 2 0 Vpu protein AAA_15 PF13175.1 KEY65998.1 - 0.46 9.4 0.0 0.79 8.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain E1-E2_ATPase PF00122.15 KEY65999.1 - 1.7e-53 180.9 1.4 3.1e-53 180.1 0.9 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEY65999.1 - 7.3e-36 123.4 5.6 7.3e-36 123.4 3.9 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEY65999.1 - 7.5e-33 114.7 0.0 2.5e-32 113.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEY65999.1 - 1.4e-17 63.3 0.0 2.9e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEY65999.1 - 2.2e-15 57.3 0.1 9.5e-15 55.2 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEY65999.1 - 6.7e-14 51.1 0.0 1.7e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KEY65999.1 - 0.0015 18.1 0.3 0.009 15.6 0.1 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF2231 PF09990.4 KEY65999.1 - 0.14 12.5 6.0 0.42 10.9 1.5 3.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) Spherulin4 PF12138.3 KEY66001.1 - 2.9e-40 138.2 1.5 3.4e-40 138.0 1.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 GMC_oxred_N PF00732.14 KEY66002.1 - 2.1e-28 99.3 0.0 4.3e-28 98.3 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY66002.1 - 3.3e-21 76.0 0.1 6.5e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KEY66002.1 - 4.1e-11 42.3 0.5 5.4e-06 25.5 0.4 2.6 3 0 0 3 3 3 2 FAD binding domain FAD_oxidored PF12831.2 KEY66002.1 - 3.8e-07 29.5 1.5 1e-05 24.8 0.6 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 KEY66002.1 - 1.4e-06 27.4 1.0 0.00056 18.9 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEY66002.1 - 4.1e-05 23.5 0.9 0.002 18.0 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEY66002.1 - 7.4e-05 21.7 1.1 8.4e-05 21.5 0.1 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 KEY66002.1 - 9.3e-05 21.0 0.6 9.3e-05 21.0 0.4 2.5 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 KEY66002.1 - 0.00044 19.4 0.2 0.00089 18.4 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 KEY66002.1 - 0.0059 15.5 0.7 0.01 14.7 0.5 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 KEY66002.1 - 0.0066 15.5 0.9 0.013 14.5 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KEY66002.1 - 0.0079 16.2 2.3 0.01 15.8 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KEY66002.1 - 0.014 14.0 0.7 0.021 13.4 0.5 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 KEY66002.1 - 0.024 14.6 0.8 5.2 7.0 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY66002.1 - 0.16 12.3 0.6 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AAA_22 PF13401.1 KEY66003.1 - 1.6e-05 25.0 0.0 4.2e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEY66003.1 - 7.7e-05 22.7 0.3 0.0087 16.0 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 KEY66003.1 - 0.00041 20.1 0.2 0.0012 18.6 0.0 1.8 2 1 0 2 2 2 1 Archaeal ATPase AAA_25 PF13481.1 KEY66003.1 - 0.0023 17.3 0.0 0.0058 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KEY66003.1 - 0.0063 15.5 0.0 0.012 14.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 KEY66003.1 - 0.03 13.4 0.1 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF815 PF05673.8 KEY66003.1 - 0.069 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NTPase_1 PF03266.10 KEY66003.1 - 0.11 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA PF00004.24 KEY66003.1 - 0.16 12.2 0.8 1.2 9.3 0.1 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) BTB PF00651.26 KEY66005.1 - 0.0018 18.2 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain PTPS PF01242.14 KEY66005.1 - 0.055 13.1 0.1 0.096 12.3 0.1 1.3 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase Lipase_GDSL_2 PF13472.1 KEY66006.1 - 1.7e-10 41.3 0.1 2.6e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CBM_1 PF00734.13 KEY66006.1 - 5.3e-07 29.1 6.5 1.3e-06 27.9 4.5 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL PF00657.17 KEY66006.1 - 9.4e-07 28.8 0.1 6e-06 26.2 0.1 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase EHN PF06441.7 KEY66007.1 - 1.1e-38 131.6 1.0 1.7e-38 130.9 0.1 1.8 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KEY66007.1 - 3.3e-12 46.7 2.9 4.9e-12 46.2 2.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Mrr_cat PF04471.7 KEY66007.1 - 0.059 13.1 0.0 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease AAA PF00004.24 KEY66008.1 - 3.5e-19 69.2 0.0 8.5e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEY66008.1 - 0.00071 19.6 0.0 0.0025 17.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KEY66008.1 - 0.0011 19.7 0.0 0.0059 17.4 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEY66008.1 - 0.0032 17.6 0.0 0.016 15.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 KEY66008.1 - 0.0033 17.1 0.0 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KEY66008.1 - 0.023 14.1 0.0 0.049 13.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 KEY66008.1 - 0.024 14.5 0.0 0.072 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KEY66008.1 - 0.025 14.4 0.0 0.064 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KEY66008.1 - 0.047 13.4 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 KEY66008.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Clr5 PF14420.1 KEY66009.1 - 4.2e-14 52.1 3.2 9.7e-14 51.0 2.2 1.7 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 KEY66009.1 - 5.8e-13 48.5 6.7 2.5e-08 33.7 0.9 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEY66009.1 - 0.0001 22.8 0.2 0.0001 22.8 0.2 3.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEY66009.1 - 0.00024 20.7 1.9 0.083 12.8 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEY66009.1 - 0.0034 17.0 1.7 0.18 11.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEY66009.1 - 0.0044 16.6 0.3 0.0044 16.6 0.2 2.4 3 0 0 3 3 3 1 TPR repeat TPR_10 PF13374.1 KEY66009.1 - 0.014 15.2 3.8 0.68 9.9 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KEY66009.1 - 0.016 15.5 0.1 0.016 15.5 0.0 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.1 KEY66009.1 - 0.029 14.6 0.1 0.59 10.5 0.0 2.9 2 0 0 2 2 2 0 Pentatricopeptide repeat domain TPR_14 PF13428.1 KEY66009.1 - 0.048 14.3 17.3 2 9.2 0.0 6.1 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEY66009.1 - 0.18 11.4 3.6 0.37 10.4 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Zn_clus PF00172.13 KEY66010.1 - 7.4e-08 32.1 6.7 1.7e-07 31.0 4.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHO4 PF01384.15 KEY66011.1 - 4.3e-112 373.9 17.9 5.5e-112 373.6 12.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family HTH_IclR PF09339.5 KEY66011.1 - 0.093 12.3 0.1 1.3 8.6 0.0 2.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain AA_permease PF00324.16 KEY66012.1 - 5.3e-117 391.0 32.8 6e-117 390.9 22.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEY66012.1 - 4.7e-32 111.0 37.6 5.7e-32 110.8 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_M24 PF00557.19 KEY66013.1 - 2.8e-41 141.4 0.0 3.5e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Cutinase PF01083.17 KEY66014.1 - 1.6e-26 93.1 0.1 1.6e-26 93.1 0.1 1.8 2 0 0 2 2 2 1 Cutinase PE-PPE PF08237.6 KEY66014.1 - 0.028 13.8 2.1 0.29 10.5 0.0 2.4 2 1 0 2 2 2 0 PE-PPE domain Presenilin PF01080.12 KEY66014.1 - 0.54 9.0 7.5 0.77 8.5 5.2 1.1 1 0 0 1 1 1 0 Presenilin His_Phos_1 PF00300.17 KEY66015.1 - 3.4e-22 79.2 0.1 1.1e-21 77.5 0.1 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3659 PF12396.3 KEY66016.1 - 3e-115 375.9 53.5 1.5e-24 85.4 0.8 6.9 6 0 0 6 6 6 6 Protein of unknown function (DUF3659) Syntaxin_2 PF14523.1 KEY66016.1 - 2 8.5 6.2 0.82 9.7 0.2 3.4 4 1 0 4 4 4 0 Syntaxin-like protein DUF3659 PF12396.3 KEY66017.1 - 6.9e-20 70.4 9.3 5.9e-15 54.6 0.9 2.2 1 1 0 2 2 2 2 Protein of unknown function (DUF3659) PBP1_TM PF14812.1 KEY66018.1 - 1.7 9.0 6.6 3.8 7.8 4.6 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pec_lyase_C PF00544.14 KEY66021.1 - 1e-27 96.9 12.6 7.2e-26 90.9 8.8 2.2 1 1 0 1 1 1 1 Pectate lyase FAD_binding_4 PF01565.18 KEY66022.1 - 6.6e-14 51.5 0.0 1e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.20 KEY66023.1 - 1.9e-29 102.7 2.2 2.5e-29 102.3 1.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY66023.1 - 8.9e-29 100.9 0.0 1.1e-28 100.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY66023.1 - 3.4e-17 62.6 0.9 4.8e-17 62.1 0.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY66023.1 - 9.7e-05 21.9 0.0 0.00016 21.2 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEY66023.1 - 0.0016 17.2 0.0 0.0024 16.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family SAGA-Tad1 PF12767.2 KEY66023.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Lactamase_B_2 PF12706.2 KEY66024.1 - 8.9e-20 71.0 0.0 1.4e-19 70.3 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KEY66024.1 - 1.2e-12 47.8 0.3 2.6e-12 46.7 0.2 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KEY66024.1 - 6.7e-05 22.6 2.3 6.7e-05 22.6 1.6 2.0 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily DAO PF01266.19 KEY66025.1 - 2.4e-43 148.4 0.2 2.9e-43 148.1 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.21 KEY66025.1 - 9.8e-14 50.7 0.1 2.1e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FAD_oxidored PF12831.2 KEY66025.1 - 2.3e-08 33.5 0.8 0.0021 17.2 0.5 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY66025.1 - 5.9e-07 29.4 0.6 1.4e-06 28.1 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEY66025.1 - 1.4e-06 27.4 0.8 2.2e-06 26.7 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KEY66025.1 - 1.1e-05 25.5 0.5 0.00045 20.3 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEY66025.1 - 1.7e-05 24.0 0.4 3.8e-05 22.9 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KEY66025.1 - 3.4e-05 23.7 0.1 7.6e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY66025.1 - 5.9e-05 22.1 0.6 0.0012 17.7 0.2 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 KEY66025.1 - 0.00028 21.2 0.4 0.0051 17.1 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEY66025.1 - 0.0011 18.1 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.13 KEY66025.1 - 0.0017 18.0 0.3 0.0029 17.3 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KEY66025.1 - 0.0036 15.8 0.1 0.03 12.8 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 KEY66025.1 - 0.0044 15.9 0.3 0.014 14.2 0.3 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KEY66025.1 - 0.029 14.1 0.0 0.27 10.9 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 KEY66025.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 KEY66025.1 - 0.096 12.4 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 KEY66025.1 - 0.11 11.9 1.4 0.13 11.5 0.4 1.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.14 KEY66026.1 - 2.1e-15 56.6 0.4 2.6e-14 53.0 0.3 2.1 1 1 0 1 1 1 1 FAD binding domain An_peroxidase PF03098.10 KEY66027.1 - 3.2e-128 428.4 0.0 3.7e-128 428.1 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Acyl_transf_3 PF01757.17 KEY66028.1 - 1.4e-30 106.2 33.8 1.2e-29 103.2 23.5 2.0 1 1 0 1 1 1 1 Acyltransferase family RseC_MucC PF04246.7 KEY66028.1 - 2.5 7.6 5.2 1.2 8.7 0.2 2.8 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DUF4131 PF13567.1 KEY66030.1 - 2.7 7.3 6.0 1.5 8.1 1.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) COesterase PF00135.23 KEY66031.1 - 0.066 11.9 0.1 0.074 11.7 0.1 1.1 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_6 PF12697.2 KEY66032.1 - 6.6e-18 65.4 4.7 8.5e-18 65.0 3.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY66032.1 - 2.9e-08 33.6 0.1 6.6e-08 32.4 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY66032.1 - 3.1e-05 23.6 0.1 9.3e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KEY66032.1 - 0.0026 17.5 0.0 0.0052 16.6 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 KEY66033.1 - 2.8e-13 50.2 11.0 4.6e-13 49.5 7.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY66033.1 - 1.1e-11 44.6 0.1 2.4e-11 43.5 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 KEY66033.1 - 6.5e-08 32.1 3.3 0.0043 16.3 0.0 2.2 2 0 0 2 2 2 2 Secretory lipase Peptidase_S9 PF00326.16 KEY66033.1 - 2.7e-07 30.0 0.6 0.0022 17.2 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 KEY66033.1 - 0.063 12.5 0.0 2.9 7.1 0.1 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 KEY66033.1 - 0.064 12.8 0.1 0.88 9.0 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.3 KEY66033.1 - 0.13 11.6 0.0 10 5.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.11 KEY66034.1 - 5.6e-52 176.3 0.0 1.3e-30 106.4 0.0 2.0 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KEY66034.1 - 1.6e-12 47.3 0.2 4.5e-12 45.9 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY66034.1 - 5.1e-12 46.1 2.0 1.3e-06 28.4 1.4 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KEY66034.1 - 5.4e-06 26.1 0.0 0.024 14.2 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 KEY66034.1 - 0.00044 20.0 0.0 0.0012 18.6 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein FSH1 PF03959.8 KEY66034.1 - 0.00064 19.2 0.0 0.0035 16.7 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 KEY66034.1 - 0.0011 18.2 0.0 0.0019 17.5 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 KEY66034.1 - 0.0015 18.1 0.0 0.73 9.3 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEY66034.1 - 0.01 15.0 0.4 0.12 11.5 0.0 2.4 3 0 0 3 3 3 0 Prolyl oligopeptidase family Cutinase PF01083.17 KEY66034.1 - 0.034 13.8 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Cutinase DUF2974 PF11187.3 KEY66034.1 - 0.046 13.0 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.3 KEY66034.1 - 0.11 12.3 0.0 21 5.0 0.0 2.4 2 0 0 2 2 2 0 Putative lysophospholipase FAD_binding_4 PF01565.18 KEY66035.1 - 5.6e-25 87.4 2.1 9.6e-25 86.6 1.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY66035.1 - 9.6e-05 22.2 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Methyltransf_23 PF13489.1 KEY66036.1 - 6.5e-14 51.9 0.0 9.1e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY66036.1 - 2.1e-11 44.3 0.0 3.4e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY66036.1 - 2.2e-08 33.8 0.0 2.8e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY66036.1 - 6.2e-08 33.0 0.0 0.0014 19.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 KEY66036.1 - 4e-07 30.4 0.0 0.0016 18.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.13 KEY66036.1 - 3.3e-06 26.4 0.0 0.0088 15.1 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEY66036.1 - 1e-05 25.8 0.0 0.00013 22.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY66036.1 - 0.0088 16.0 0.1 0.053 13.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 KEY66036.1 - 0.027 13.9 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MTS PF05175.9 KEY66036.1 - 0.058 12.7 0.0 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain His_Phos_1 PF00300.17 KEY66037.1 - 8.5e-32 110.4 0.0 1e-31 110.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Cortex-I_coil PF09304.5 KEY66038.1 - 0.003 17.5 6.7 0.0034 17.4 4.7 1.1 1 0 0 1 1 1 1 Cortexillin I, coiled coil DUF3366 PF11846.3 KEY66038.1 - 0.057 13.2 0.2 0.068 13.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) RskA PF10099.4 KEY66038.1 - 0.12 12.1 6.4 0.04 13.6 2.6 1.5 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Atg14 PF10186.4 KEY66038.1 - 0.52 9.2 9.8 0.61 8.9 6.8 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 UCH PF00443.24 KEY66039.1 - 9.5e-53 179.0 0.0 1.2e-52 178.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEY66039.1 - 2.7e-18 66.4 0.2 1.8e-17 63.7 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KEY66039.1 - 8e-11 41.1 0.3 1.9e-10 40.0 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KEY66039.1 - 0.051 13.2 0.2 0.13 12.0 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ARPC4 PF05856.7 KEY66040.1 - 6.4e-74 246.9 3.8 7.9e-74 246.6 2.7 1.1 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) RRM_6 PF14259.1 KEY66041.1 - 1.4e-06 28.1 0.0 2.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY66041.1 - 0.088 12.6 0.0 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_23 PF13489.1 KEY66042.1 - 3.6e-16 59.2 0.1 5.5e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY66042.1 - 4.1e-09 36.8 0.0 3.3e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY66042.1 - 1.5e-06 28.6 0.0 5.3e-05 23.6 0.0 3.0 3 1 0 3 3 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY66042.1 - 2.6e-05 24.7 0.0 0.00055 20.4 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY66042.1 - 2.7e-05 23.8 0.0 0.00032 20.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY66042.1 - 2.8e-05 24.4 0.0 0.00027 21.2 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY66042.1 - 0.016 14.2 0.0 0.39 9.7 0.0 2.4 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KEY66042.1 - 0.017 15.1 0.0 0.051 13.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 KEY66042.1 - 0.023 13.7 0.0 0.038 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 KEY66042.1 - 0.024 14.0 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 KEY66042.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 KEY66042.1 - 0.07 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CRAL_TRIO PF00650.15 KEY66043.1 - 3.7e-14 52.5 0.0 5.4e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KEY66043.1 - 0.0047 17.0 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DPCD PF14913.1 KEY66043.1 - 0.041 12.9 0.0 0.08 12.0 0.0 1.4 1 0 0 1 1 1 0 DPCD protein family SET PF00856.23 KEY66044.1 - 2.7e-19 70.0 2.8 3e-19 69.9 0.3 2.4 2 1 0 2 2 2 1 SET domain zf-DHHC PF01529.15 KEY66045.1 - 2.8e-25 88.7 0.2 2.8e-25 88.7 0.1 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase ISK_Channel PF02060.10 KEY66045.1 - 0.012 15.1 2.0 0.02 14.4 0.1 2.2 3 0 0 3 3 3 0 Slow voltage-gated potassium channel TRP PF06011.7 KEY66045.1 - 5 5.5 8.7 4 5.8 1.8 2.1 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel IMS PF00817.15 KEY66046.1 - 4.2e-41 140.2 0.0 6.5e-41 139.6 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KEY66046.1 - 3.6e-13 49.5 0.0 7.7e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf-C2H2_4 PF13894.1 KEY66046.1 - 0.0026 17.9 0.3 0.0091 16.2 0.2 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger IMS_HHH PF11798.3 KEY66046.1 - 0.0049 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif zf-C2H2 PF00096.21 KEY66046.1 - 0.011 16.0 0.1 0.025 14.9 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type IBN_N PF03810.14 KEY66048.1 - 6.7e-15 54.7 5.5 5.9e-13 48.5 0.1 4.1 5 0 0 5 5 5 2 Importin-beta N-terminal domain Cse1 PF08506.5 KEY66048.1 - 5e-09 35.1 0.2 4e-08 32.2 0.1 2.2 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.7 KEY66048.1 - 2.5e-05 24.2 1.9 0.00014 21.8 0.1 3.1 3 0 0 3 3 3 1 Exportin 1-like protein GRIP PF01465.15 KEY66048.1 - 0.00093 18.6 0.1 0.015 14.8 0.0 2.9 2 0 0 2 2 2 1 GRIP domain HEAT_2 PF13646.1 KEY66048.1 - 0.00094 19.4 1.9 4.1 7.7 0.2 3.9 3 0 0 3 3 3 2 HEAT repeats ISN1 PF06437.6 KEY66049.1 - 1.6e-167 557.3 0.0 2e-167 557.0 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Pkinase PF00069.20 KEY66050.1 - 2e-56 191.0 0.0 2.8e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY66050.1 - 4.5e-26 91.4 0.5 2.2e-25 89.2 0.3 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY66050.1 - 0.015 14.3 0.1 0.031 13.2 0.1 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 KEY66050.1 - 0.19 10.7 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family p450 PF00067.17 KEY66051.1 - 2.1e-10 39.7 0.0 2.9e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GIDE PF12483.3 KEY66052.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 E3 Ubiquitin ligase adh_short PF00106.20 KEY66053.1 - 6.5e-10 39.1 0.2 1.3e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY66053.1 - 0.0013 18.4 0.1 0.0019 17.8 0.1 1.2 1 0 0 1 1 1 1 KR domain p450 PF00067.17 KEY66054.1 - 2.4e-31 108.7 0.0 4.2e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 KEY66055.1 - 8.1e-20 70.7 2.3 1.5e-19 69.8 1.6 1.4 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.9 KEY66056.1 - 3.8e-79 265.9 0.5 4.8e-79 265.5 0.4 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 KEY66056.1 - 1.8e-27 95.5 0.1 4e-27 94.3 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Aldo_ket_red PF00248.16 KEY66057.1 - 2.3e-55 187.4 0.0 3e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SIS PF01380.17 KEY66058.1 - 1e-12 47.7 0.0 1.6e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.1 KEY66058.1 - 0.042 13.5 0.0 0.11 12.1 0.0 1.7 1 1 0 1 1 1 0 SIS domain MFS_1 PF07690.11 KEY66059.1 - 1.1e-32 113.1 36.3 1.1e-32 113.1 25.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY66059.1 - 3.9e-11 42.2 7.8 3.9e-11 42.2 5.4 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 KEY66059.1 - 3.1e-09 35.5 3.0 5e-09 34.9 2.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF554 PF04474.7 KEY66059.1 - 0.00054 19.1 3.2 0.0026 16.9 2.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF554) MFS_3 PF05977.8 KEY66059.1 - 0.0061 14.7 2.9 0.01 13.9 2.0 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.11 KEY66060.1 - 1e-22 80.3 23.4 1e-22 80.3 16.2 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY66060.1 - 0.01 14.4 35.3 0.39 9.2 24.5 2.8 1 1 0 1 1 1 0 Sugar (and other) transporter FAD_binding_4 PF01565.18 KEY66061.1 - 2.5e-22 78.8 2.0 5.7e-22 77.6 1.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY66061.1 - 7.7e-11 41.7 0.0 1.7e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like PEP_mutase PF13714.1 KEY66062.1 - 1.8e-71 240.1 3.4 3.6e-71 239.1 2.4 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase HpcH_HpaI PF03328.9 KEY66062.1 - 1e-28 99.7 0.1 5.8e-28 97.2 0.0 2.0 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family ICL PF00463.16 KEY66062.1 - 1.1e-05 23.8 0.6 5.9e-05 21.4 0.1 2.1 1 1 1 2 2 2 1 Isocitrate lyase family Fungal_trans PF04082.13 KEY66062.1 - 0.00018 20.4 0.1 0.0003 19.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_1_2 PF00155.16 KEY66063.1 - 1.8e-69 234.4 0.0 2e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II FAD_binding_3 PF01494.14 KEY66064.1 - 2.5e-42 145.2 0.1 3.9e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Amidohydro_1 PF01979.15 KEY66066.1 - 6.3e-06 26.0 0.0 1.9e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KEY66066.1 - 0.034 14.1 0.3 0.41 10.6 0.0 2.1 2 0 0 2 2 2 0 Amidohydrolase TPP_enzyme_M PF00205.17 KEY66066.1 - 0.041 13.6 0.0 0.49 10.1 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DpnII PF04556.7 KEY66067.1 - 0.053 12.5 0.5 0.069 12.2 0.3 1.1 1 0 0 1 1 1 0 DpnII restriction endonuclease DUF3425 PF11905.3 KEY66068.1 - 3.5e-26 91.7 1.8 5.5e-26 91.0 0.8 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) adh_short PF00106.20 KEY66069.1 - 7.5e-14 51.9 0.1 1.2e-13 51.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY66069.1 - 7.1e-08 32.5 0.0 1.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY66069.1 - 8.6e-06 25.5 0.5 1.5e-05 24.7 0.3 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY66069.1 - 0.025 13.9 0.2 0.072 12.5 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.18 KEY66071.1 - 1.2e-22 79.8 1.0 2.5e-22 78.8 0.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY66071.1 - 1.6e-07 31.0 0.0 4.7e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 KEY66072.1 - 1.6e-30 106.2 2.0 2e-30 105.9 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY66072.1 - 1.2e-29 103.8 0.5 1.4e-29 103.5 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY66072.1 - 2.1e-17 63.3 0.9 2.8e-17 62.9 0.6 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY66072.1 - 0.0012 18.3 0.4 0.0016 17.9 0.3 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family S4 PF01479.20 KEY66072.1 - 0.039 13.4 0.0 0.15 11.5 0.0 2.0 1 0 0 1 1 1 0 S4 domain CBM_1 PF00734.13 KEY66073.1 - 2.7e-12 46.1 4.9 2.7e-12 46.1 3.4 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain AA_permease_2 PF13520.1 KEY66074.1 - 2.7e-62 210.7 53.5 3.3e-62 210.4 37.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEY66074.1 - 1.5e-28 99.3 48.9 2.2e-28 98.8 33.9 1.1 1 0 0 1 1 1 1 Amino acid permease NMT1 PF09084.6 KEY66075.1 - 2.9e-77 259.1 0.0 3.8e-77 258.7 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 KEY66075.1 - 2.4e-09 36.9 0.2 0.029 13.7 0.0 3.1 2 1 1 3 3 3 3 NMT1-like family TroA PF01297.12 KEY66075.1 - 0.12 11.5 0.0 2.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Periplasmic solute binding protein family Imm-NTF2-2 PF15631.1 KEY66076.1 - 0.77 9.7 5.7 1.6 8.7 0.0 3.5 4 0 0 4 4 4 0 NTF2 fold immunity protein Glyco_hydro_61 PF03443.9 KEY66077.1 - 4.3e-71 239.1 0.0 4.9e-71 239.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SurE PF01975.12 KEY66078.1 - 3.6e-14 52.5 0.0 4.5e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Sugar_tr PF00083.19 KEY66079.1 - 8.4e-118 393.7 19.4 1e-117 393.5 13.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY66079.1 - 1.1e-20 73.7 31.6 1.4e-20 73.3 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.18 KEY66080.1 - 1.4e-20 73.2 1.0 2.2e-20 72.5 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY66080.1 - 9.5e-08 31.8 0.0 2.2e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like PHO4 PF01384.15 KEY66081.1 - 2e-109 365.2 11.4 2.3e-109 364.9 7.9 1.0 1 0 0 1 1 1 1 Phosphate transporter family Glycophorin_A PF01102.13 KEY66081.1 - 0.073 12.8 0.5 0.71 9.6 0.0 2.4 2 0 0 2 2 2 0 Glycophorin A adh_short_C2 PF13561.1 KEY66082.1 - 1.1e-26 94.0 0.2 2.1e-26 93.1 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEY66082.1 - 2e-26 92.9 3.7 2e-26 92.9 2.6 1.8 2 0 0 2 2 2 1 short chain dehydrogenase Fungal_trans PF04082.13 KEY66082.1 - 1.1e-19 70.3 0.0 2e-19 69.5 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain KR PF08659.5 KEY66082.1 - 4.6e-10 39.4 1.0 1e-09 38.3 0.7 1.6 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.10 KEY66082.1 - 0.00048 19.7 0.2 0.0014 18.3 0.1 1.8 1 0 0 1 1 1 1 YjeF-related protein N-terminus THF_DHG_CYH_C PF02882.14 KEY66082.1 - 0.027 13.5 1.5 0.12 11.4 0.1 2.7 4 0 0 4 4 4 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.12 KEY66082.1 - 0.11 12.9 2.7 0.41 11.1 1.9 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MbeB_N PF04837.7 KEY66082.1 - 0.21 11.7 1.9 0.24 11.5 0.2 1.9 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Cyclase PF04199.8 KEY66083.1 - 9.6e-16 57.9 0.0 1.8e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Putative cyclase Glyco_hydro_3 PF00933.16 KEY66084.1 - 2.5e-85 286.0 0.0 3.6e-85 285.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY66084.1 - 1.1e-41 142.8 0.0 1.4e-40 139.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEY66084.1 - 1.6e-19 69.6 0.0 3.6e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain G-alpha PF00503.15 KEY66085.1 - 1.1e-118 396.3 0.7 1.3e-118 396.0 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KEY66085.1 - 1.8e-13 50.0 0.2 9.2e-08 31.5 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEY66085.1 - 0.00035 19.7 0.9 0.087 11.9 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 KEY66085.1 - 0.023 14.1 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 KEY66085.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KEY66085.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Spermine_synth PF01564.12 KEY66087.1 - 1.5e-93 312.3 0.1 7.4e-93 309.9 0.0 2.0 2 1 0 2 2 2 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 KEY66087.1 - 0.0072 16.9 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY66087.1 - 0.013 15.1 0.0 0.079 12.6 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 KEY66087.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 KEY66087.1 - 0.093 11.9 0.1 0.42 9.7 0.0 1.9 1 1 2 3 3 3 0 O-methyltransferase CN_hydrolase PF00795.17 KEY66088.1 - 2.9e-33 114.7 0.0 4.3e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Kelch_6 PF13964.1 KEY66088.1 - 0.11 12.6 0.0 1.1 9.4 0.0 2.5 3 0 0 3 3 3 0 Kelch motif Claudin_2 PF13903.1 KEY66089.1 - 1.6e-07 31.1 3.8 2.3e-07 30.6 2.7 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction ABC_membrane PF00664.18 KEY66089.1 - 9.3 5.5 8.1 5.5 6.3 0.0 2.6 2 1 1 3 3 3 0 ABC transporter transmembrane region PhyH PF05721.8 KEY66090.1 - 2e-60 204.4 0.0 2.4e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF2373 PF10180.4 KEY66091.1 - 1.1e-21 76.0 1.2 2.7e-21 74.8 0.1 2.1 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) Proteasome PF00227.21 KEY66092.1 - 1e-47 161.8 0.0 1.4e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEY66092.1 - 7.8e-10 37.8 0.1 7.8e-10 37.8 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF2011 PF09428.5 KEY66093.1 - 0.00018 21.3 0.1 0.00026 20.8 0.1 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Protamine_P2 PF00841.14 KEY66093.1 - 0.047 14.2 0.8 0.077 13.5 0.5 1.3 1 0 0 1 1 1 0 Sperm histone P2 UPF0546 PF10639.4 KEY66094.1 - 4.1e-29 100.6 0.0 5.5e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 DUF1211 PF06736.6 KEY66094.1 - 0.068 13.3 0.0 0.15 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) Con-6 PF10346.4 KEY66095.1 - 6.9e-31 105.3 5.9 5.4e-17 60.9 0.4 2.1 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.2 KEY66095.1 - 0.0014 18.1 1.2 0.013 14.9 0.1 2.1 2 0 0 2 2 2 1 SpoIIIAH-like protein Toxin_52 PF15605.1 KEY66095.1 - 0.0087 15.9 1.2 0.16 11.9 0.1 2.1 1 1 1 2 2 2 1 Putative toxin 52 WD40 PF00400.27 KEY66096.1 - 7.4e-48 158.7 16.1 1.3e-11 43.8 0.0 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 KEY66096.1 - 1.5e-06 26.6 4.6 0.3 9.1 0.1 4.7 4 1 1 5 5 5 3 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 KEY66096.1 - 0.00098 18.0 0.0 0.0013 17.6 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region Yeast-kill-tox PF09207.6 KEY66096.1 - 0.0021 18.4 0.7 0.079 13.3 0.3 2.7 2 0 0 2 2 2 1 Yeast killer toxin Nucleoporin_N PF08801.6 KEY66096.1 - 0.025 13.3 0.3 2.7 6.6 0.0 3.3 2 1 1 3 3 3 0 Nup133 N terminal like DUF3312 PF11768.3 KEY66096.1 - 0.04 12.1 0.0 0.13 10.4 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) Hira PF07569.6 KEY66096.1 - 0.058 12.6 1.0 12 5.0 0.0 3.2 1 1 2 3 3 3 0 TUP1-like enhancer of split HPS3_N PF14761.1 KEY66096.1 - 0.076 12.4 0.0 0.38 10.1 0.0 2.0 2 1 0 2 2 2 0 Hermansky-Pudlak syndrome 3 FHA PF00498.21 KEY66097.1 - 8.5e-11 41.8 0.1 1.9e-10 40.6 0.0 1.7 2 0 0 2 2 2 1 FHA domain Daxx PF03344.10 KEY66097.1 - 1.3 7.4 28.8 2.1 6.7 20.0 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 KEY66097.1 - 3.9 5.2 19.3 6.3 4.5 13.4 1.3 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.6 KEY66097.1 - 9.3 6.0 11.9 25 4.6 8.3 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal IFRD PF05004.8 KEY66098.1 - 1.5e-23 83.3 0.7 1.9e-23 83.0 0.5 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Toprim_N PF08275.6 KEY66098.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 DNA primase catalytic core, N-terminal domain V-ATPase_H_N PF03224.9 KEY66098.1 - 0.16 11.0 0.3 1.7 7.6 0.2 2.1 1 1 0 1 1 1 0 V-ATPase subunit H Abhydrolase_2 PF02230.11 KEY66099.1 - 0.058 12.8 0.1 0.093 12.1 0.1 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Aminotran_5 PF00266.14 KEY66100.1 - 2.5e-94 316.0 0.0 3e-94 315.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KEY66100.1 - 3.4e-10 39.5 0.0 5.5e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KEY66100.1 - 1.8e-06 27.2 0.1 5.5e-06 25.6 0.1 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KEY66100.1 - 0.00083 17.7 0.0 0.0014 17.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.14 KEY66100.1 - 0.00087 17.8 0.0 0.0013 17.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain BAR PF03114.13 KEY66101.1 - 1.5e-63 214.3 6.3 1.9e-63 214.0 4.4 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KEY66101.1 - 1.2e-15 56.5 0.1 2.6e-15 55.5 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KEY66101.1 - 1.3e-13 50.2 0.1 2.5e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KEY66101.1 - 4.2e-11 42.1 0.3 1.9e-10 40.0 0.0 2.2 3 0 0 3 3 3 1 Variant SH3 domain Arfaptin PF06456.8 KEY66101.1 - 0.62 9.3 8.7 4.6 6.5 6.0 2.0 1 1 0 1 1 1 0 Arfaptin-like domain TMPIT PF07851.8 KEY66101.1 - 0.82 8.6 3.7 0.32 10.0 0.1 1.8 1 1 0 2 2 2 0 TMPIT-like protein F-box PF00646.28 KEY66102.1 - 0.0074 15.9 0.0 0.038 13.6 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KEY66102.1 - 0.04 13.6 0.0 0.44 10.3 0.0 2.5 2 0 0 2 2 2 0 F-box-like HTH_8 PF02954.14 KEY66105.1 - 0.029 13.9 1.5 0.61 9.6 0.0 3.2 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family HTH_3 PF01381.17 KEY66105.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix CENP-B_N PF04218.8 KEY66105.1 - 0.13 11.7 0.0 0.33 10.3 0.0 1.7 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain DUF3716 PF12511.3 KEY66110.1 - 0.00031 20.2 4.3 0.0007 19.1 3.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) 7tm_2 PF00002.19 KEY66111.1 - 9.2e-05 21.6 11.1 0.00035 19.7 7.7 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Cellulase PF00150.13 KEY66112.1 - 3.5e-35 121.5 0.1 4.1e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CRT10 PF08728.5 KEY66113.1 - 3.4e-16 58.4 0.0 6.7e-12 44.2 0.0 2.2 2 0 0 2 2 2 2 CRT10 Nuclease_act PF08133.6 KEY66113.1 - 0.013 15.0 0.4 0.027 13.9 0.2 1.5 1 0 0 1 1 1 0 Anticodon nuclease activator family DUF961 PF06125.6 KEY66113.1 - 0.14 12.3 0.0 0.4 10.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF961) TFIIA PF03153.8 KEY66113.1 - 0.63 9.8 3.6 0.98 9.2 2.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ammonium_transp PF00909.16 KEY66114.1 - 6.6e-113 377.1 31.7 7.6e-113 376.9 21.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Epiglycanin_C PF14654.1 KEY66114.1 - 0.048 13.6 0.5 1.9 8.5 0.1 2.7 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region His_Phos_2 PF00328.17 KEY66115.1 - 1.9e-40 139.2 0.0 2.3e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TauD PF02668.11 KEY66117.1 - 5e-19 68.9 0.1 7e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KEY66117.1 - 0.042 12.7 0.1 0.07 12.0 0.0 1.3 1 0 0 1 1 1 0 CsiD Zn_clus PF00172.13 KEY66118.1 - 0.0036 17.1 3.8 0.007 16.2 2.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mucin PF01456.12 KEY66119.1 - 4.2 7.1 22.5 0.16 11.7 11.1 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein Med3 PF11593.3 KEY66119.1 - 6.4 5.9 8.4 11 5.0 5.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SSP160 PF06933.6 KEY66119.1 - 6.8 4.5 14.1 11 3.8 9.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pkinase PF00069.20 KEY66120.1 - 3e-05 23.3 0.1 0.00019 20.6 0.0 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY66120.1 - 0.049 12.7 0.0 0.24 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase YcgR PF07317.7 KEY66120.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Flagellar regulator YcgR RRM_1 PF00076.17 KEY66122.1 - 3.2e-14 52.3 0.1 5.8e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY66122.1 - 6.9e-11 41.9 0.0 1.1e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY66122.1 - 3.6e-10 39.5 0.2 5.4e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gemin6 PF06372.7 KEY66122.1 - 0.11 11.7 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Gemin6 protein HhH-GPD PF00730.20 KEY66123.1 - 0.0009 19.5 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein SURF4 PF02077.10 KEY66124.1 - 9.9e-92 307.0 7.2 1.2e-91 306.8 5.0 1.1 1 0 0 1 1 1 1 SURF4 family Peptidase_A24 PF01478.13 KEY66124.1 - 1 9.5 14.3 0.2 11.8 0.4 2.7 2 1 0 2 2 2 0 Type IV leader peptidase family HeLo PF14479.1 KEY66125.1 - 7.1e-27 94.5 0.1 3e-24 85.9 0.0 3.1 2 1 0 2 2 2 2 Prion-inhibition and propagation R3H PF01424.17 KEY66125.1 - 0.13 11.9 0.0 0.44 10.2 0.0 1.9 1 0 0 1 1 1 0 R3H domain DSPn PF14671.1 KEY66126.1 - 1.1e-42 145.3 0.0 3.6e-40 137.1 0.0 3.0 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KEY66126.1 - 1.1e-16 60.6 0.0 2.8e-16 59.2 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEY66126.1 - 5.2e-07 29.2 0.4 3.9e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KEY66126.1 - 0.021 14.8 0.0 0.048 13.7 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate Pcc1 PF09341.5 KEY66127.1 - 5.1e-25 87.3 0.4 6.3e-25 87.0 0.3 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 HLH PF00010.21 KEY66128.1 - 3.8e-12 45.7 0.3 3.8e-12 45.7 0.2 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Tnp_P_element PF12017.3 KEY66128.1 - 0.24 10.5 2.8 1.1 8.4 0.2 2.2 2 0 0 2 2 2 0 Transposase protein IncA PF04156.9 KEY66128.1 - 1 8.9 7.4 2.1 7.8 1.0 2.4 2 0 0 2 2 2 0 IncA protein DivIC PF04977.10 KEY66128.1 - 4.4 6.8 10.1 0.75 9.3 1.2 2.6 2 0 0 2 2 2 0 Septum formation initiator Kelch_3 PF13415.1 KEY66129.1 - 1.2e-05 25.2 7.1 0.011 15.8 0.1 5.6 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_4 PF13418.1 KEY66129.1 - 0.0043 16.7 1.5 3.4 7.4 0.0 4.1 4 1 0 4 4 4 1 Galactose oxidase, central domain TMEM154 PF15102.1 KEY66129.1 - 0.024 14.3 0.1 0.052 13.2 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family Rax2 PF12768.2 KEY66129.1 - 0.35 10.0 3.9 0.85 8.7 0.7 2.6 2 1 1 3 3 3 0 Cortical protein marker for cell polarity Strabismus PF06638.6 KEY66129.1 - 0.44 8.7 0.8 0.62 8.2 0.6 1.1 1 0 0 1 1 1 0 Strabismus protein TAP_C PF03943.8 KEY66130.1 - 1.2e-13 50.2 0.9 2.2e-13 49.3 0.3 1.7 2 0 0 2 2 2 1 TAP C-terminal domain LRR_4 PF12799.2 KEY66130.1 - 2.1e-07 30.4 0.0 1.2e-05 24.8 0.0 2.5 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) NTF2 PF02136.15 KEY66130.1 - 8.9e-06 26.0 0.0 5.4e-05 23.5 0.0 2.4 2 1 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.1 KEY66130.1 - 0.003 17.2 0.3 0.074 12.8 0.1 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KEY66130.1 - 0.02 14.8 0.0 2.6 8.4 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.1 KEY66130.1 - 0.066 13.3 1.2 3.3 8.0 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeat DEAD PF00270.24 KEY66131.1 - 7e-20 71.1 0.0 1.5e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY66131.1 - 8.5e-20 70.4 0.2 2.1e-19 69.1 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEY66131.1 - 3.5e-19 69.3 0.0 7.7e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KEY66131.1 - 0.0013 18.8 0.0 0.005 16.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 KEY66131.1 - 0.094 11.9 0.1 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ATP-grasp_2 PF08442.5 KEY66131.1 - 0.15 11.4 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Ank_2 PF12796.2 KEY66133.1 - 4e-55 184.1 6.9 1.3e-15 57.5 0.0 10.2 3 3 5 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KEY66133.1 - 2.8e-43 143.6 23.5 5.1e-06 26.0 0.0 13.9 15 0 0 15 15 15 7 Ankyrin repeat Ank_4 PF13637.1 KEY66133.1 - 6.4e-41 138.0 5.8 1.5e-05 25.3 0.0 12.1 9 3 3 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY66133.1 - 5.3e-39 128.3 10.7 0.00012 21.9 0.0 13.8 15 1 0 15 15 15 7 Ankyrin repeat Ank_5 PF13857.1 KEY66133.1 - 7.6e-36 121.3 11.7 0.0004 20.5 0.0 11.8 9 3 2 12 12 12 7 Ankyrin repeats (many copies) DEAD PF00270.24 KEY66134.1 - 1.6e-20 73.3 0.1 3.9e-20 72.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY66134.1 - 5.8e-19 67.7 0.0 2e-16 59.6 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.5 KEY66134.1 - 7.5e-14 51.3 0.0 1.5e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 KEY66134.1 - 0.00033 20.3 0.0 0.0009 18.9 0.0 1.8 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.10 KEY66134.1 - 0.00035 20.4 0.0 0.00097 19.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit KAR9 PF08580.5 KEY66135.1 - 1.9e-140 469.3 5.4 1.9e-140 469.3 3.7 1.8 2 0 0 2 2 2 1 Yeast cortical protein KAR9 Syntaxin-6_N PF09177.6 KEY66135.1 - 4.6 7.7 8.2 8.1 6.9 0.1 3.9 4 1 1 5 5 5 0 Syntaxin 6, N-terminal HSP20 PF00011.16 KEY66137.1 - 6.5e-11 41.9 0.0 9.2e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Abhydrolase_3 PF07859.8 KEY66138.1 - 1.4e-42 145.6 0.0 2.7e-42 144.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KEY66138.1 - 0.018 13.7 0.0 0.027 13.1 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family COX17 PF05051.8 KEY66139.1 - 1.1e-19 70.1 5.4 1.4e-19 69.8 3.8 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Imm31 PF15595.1 KEY66140.1 - 0.0042 16.8 1.1 0.081 12.6 0.1 2.1 1 1 1 2 2 2 1 Immunity protein 31 ApoLp-III PF07464.6 KEY66140.1 - 0.06 13.3 8.0 0.26 11.3 5.5 1.8 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) ATP-synt_B PF00430.13 KEY66140.1 - 6 6.6 10.8 15 5.3 7.1 1.8 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Cpn60_TCP1 PF00118.19 KEY66141.1 - 2.8e-137 458.2 13.5 3.5e-137 457.9 9.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 KEY66141.1 - 0.03 13.8 0.0 0.082 12.4 0.0 1.7 1 0 0 1 1 1 0 Phage Tail Protein X AAA PF00004.24 KEY66142.1 - 2.3e-40 137.8 0.0 4.2e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEY66142.1 - 4.4e-06 26.8 0.0 0.00061 19.9 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 KEY66142.1 - 2.8e-05 23.8 0.1 0.00028 20.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KEY66142.1 - 0.00037 20.4 0.0 0.0013 18.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KEY66142.1 - 0.00039 20.4 0.0 0.0016 18.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 KEY66142.1 - 0.0017 17.3 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KEY66142.1 - 0.0046 17.7 0.1 0.014 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KEY66142.1 - 0.0096 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KEY66142.1 - 0.01 15.5 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 KEY66142.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KEY66142.1 - 0.023 14.6 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEY66142.1 - 0.033 14.3 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 KEY66142.1 - 0.036 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KEY66142.1 - 0.039 13.5 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KEY66142.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 KEY66142.1 - 0.081 12.9 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 KEY66142.1 - 0.1 12.1 0.1 0.61 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KEY66142.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 KEY66142.1 - 0.13 11.3 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KEY66142.1 - 0.15 11.4 0.2 0.48 9.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain IBR PF01485.16 KEY66143.1 - 0.02 14.7 4.3 0.02 14.7 3.0 2.5 2 1 0 2 2 2 0 IBR domain DUF1325 PF07039.6 KEY66143.1 - 0.079 12.5 0.1 0.74 9.4 0.0 2.1 2 0 0 2 2 2 0 SGF29 tudor-like domain Cytochrom_C1 PF02167.10 KEY66145.1 - 4.3e-81 271.7 0.0 5.2e-81 271.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 KEY66145.1 - 0.0044 17.1 0.0 0.0092 16.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 KEY66145.1 - 0.15 12.9 0.5 0.38 11.6 0.1 2.0 2 1 0 2 2 2 0 Cytochrome c LRR_6 PF13516.1 KEY66146.1 - 7.7e-14 50.1 8.9 0.0057 16.5 0.0 6.8 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.2 KEY66146.1 - 1.3e-09 37.4 13.2 0.00063 19.3 0.0 5.0 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEY66146.1 - 4.8e-06 25.8 3.1 8 6.9 0.0 5.9 5 1 1 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.1 KEY66146.1 - 5.5e-05 22.8 10.3 0.58 9.9 2.2 4.0 3 1 0 3 3 3 3 Leucine rich repeat LRR_7 PF13504.1 KEY66146.1 - 0.00086 19.1 0.7 78 4.1 0.1 5.5 5 0 0 5 5 5 0 Leucine rich repeat SDA1 PF05285.7 KEY66146.1 - 0.81 8.9 17.6 1.1 8.5 12.2 1.2 1 0 0 1 1 1 0 SDA1 CENP-B_dimeris PF09026.5 KEY66146.1 - 6.3 7.1 15.7 15 5.9 10.9 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SOG2 PF10428.4 KEY66147.1 - 0.16 10.5 4.7 0.22 10.1 3.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Proteasome PF00227.21 KEY66148.1 - 6.8e-45 152.6 0.1 2.3e-31 108.5 0.0 2.1 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KEY66148.1 - 3.8e-10 38.8 0.6 5.6e-10 38.3 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DNA_pol_phi PF04931.8 KEY66149.1 - 7.1e-44 149.7 48.8 9.1e-24 83.2 33.2 3.5 2 2 0 2 2 2 2 DNA polymerase phi SDA1 PF05285.7 KEY66149.1 - 0.32 10.2 30.0 0.95 8.6 20.8 1.8 1 0 0 1 1 1 0 SDA1 Rhodanese PF00581.15 KEY66150.1 - 1.2e-11 45.0 0.0 2.4e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain CwfJ_C_2 PF04676.9 KEY66151.1 - 1e-22 80.4 0.1 1.8e-22 79.6 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 KEY66151.1 - 1.4e-22 79.5 0.0 4.1e-22 78.0 0.0 1.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 DRIM PF07539.7 KEY66152.1 - 1.6e-41 140.9 0.1 8.5e-41 138.6 0.1 2.4 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.17 KEY66152.1 - 1.9e-06 27.4 2.7 0.16 12.1 0.0 7.6 6 1 1 7 7 7 1 HEAT repeat DUF3123 PF11321.3 KEY66152.1 - 0.037 14.3 0.2 0.13 12.5 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) Arm PF00514.18 KEY66152.1 - 0.079 12.8 3.5 7.2 6.5 0.0 5.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Ribosomal_60s PF00428.14 KEY66152.1 - 1.8 9.0 11.1 0.04 14.3 2.4 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-DNL PF05180.7 KEY66153.1 - 4.2e-28 96.8 0.4 5.8e-28 96.4 0.3 1.2 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 KEY66153.1 - 0.022 14.2 0.2 0.037 13.5 0.2 1.3 1 0 0 1 1 1 0 CSL zinc finger Zn_Tnp_IS1595 PF12760.2 KEY66153.1 - 5.9 6.7 6.2 19 5.1 0.4 2.4 1 1 1 2 2 2 0 Transposase zinc-ribbon domain CAP PF00188.21 KEY66154.1 - 1.1e-05 25.8 0.1 1.1e-05 25.8 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SNF5 PF04855.7 KEY66155.1 - 1.4e-84 283.4 0.0 1.9e-84 282.9 0.0 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 KEY66155.1 - 1.9e-05 23.8 0.7 5.4e-05 22.4 0.5 1.8 1 0 0 1 1 1 1 GATA zinc finger Glyco_hydro_7 PF00840.15 KEY66156.1 - 7.2e-201 667.1 16.1 8.3e-201 666.9 11.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF2567 PF10821.3 KEY66157.1 - 0.054 13.0 0.7 0.064 12.7 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) Tweety PF04906.8 KEY66157.1 - 0.12 10.8 1.1 0.14 10.5 0.8 1.1 1 0 0 1 1 1 0 Tweety NS3_envE PF02723.9 KEY66157.1 - 0.21 11.5 3.0 0.29 11.0 2.1 1.2 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E Transglut_core3 PF13471.1 KEY66157.1 - 0.29 10.9 2.0 0.78 9.5 0.4 2.0 2 0 0 2 2 2 0 Transglutaminase-like superfamily Orexin PF02072.10 KEY66157.1 - 1.2 8.9 5.0 0.99 9.2 2.0 1.7 1 1 1 2 2 2 0 Prepro-orexin Fungal_trans PF04082.13 KEY66158.1 - 6.8e-22 77.5 1.4 1.7e-21 76.2 0.9 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY66158.1 - 3.7e-07 29.9 9.2 3.7e-07 29.9 6.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 KEY66158.1 - 0.72 9.1 30.7 1.1 8.5 21.2 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 KEY66158.1 - 5.4 5.1 71.5 8.7 4.4 49.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 KEY66158.1 - 7.7 6.7 12.0 15 5.8 8.3 1.5 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 KEY66159.1 - 6e-18 64.6 0.0 1.1e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY66159.1 - 0.0065 16.3 5.7 0.0065 16.3 4.0 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_11 PF13414.1 KEY66160.1 - 0.0017 17.9 0.0 0.021 14.4 0.0 2.7 3 0 0 3 3 3 1 TPR repeat TPR_9 PF13371.1 KEY66160.1 - 0.0053 16.5 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat NARP1 PF12569.3 KEY66160.1 - 0.044 12.5 0.0 0.074 11.7 0.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sod_Cu PF00080.15 KEY66161.1 - 2.2e-18 66.7 0.0 3e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) A_amylase_inhib PF01356.14 KEY66161.1 - 1 9.2 3.5 0.55 10.0 0.2 2.2 3 0 0 3 3 3 0 Alpha amylase inhibitor Alpha_GJ PF03229.8 KEY66161.1 - 2.1 8.6 15.9 0.18 12.1 7.2 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J AA_permease_2 PF13520.1 KEY66162.1 - 0.0088 14.6 0.2 0.01 14.3 0.2 1.0 1 0 0 1 1 1 1 Amino acid permease DctQ PF04290.7 KEY66162.1 - 0.029 14.1 0.2 0.033 13.9 0.1 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF3980 PF13140.1 KEY66162.1 - 0.062 13.5 2.1 0.083 13.1 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3980) Sdh_cyt PF01127.17 KEY66162.1 - 0.08 12.7 1.0 0.1 12.4 0.7 1.1 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit adh_short_C2 PF13561.1 KEY66163.1 - 1.2e-29 103.8 0.0 1.4e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEY66163.1 - 3.6e-29 101.8 0.0 5e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY66163.1 - 1.3e-11 44.5 0.0 1.7e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KEY66163.1 - 0.0019 17.9 0.1 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 KEY66163.1 - 0.0026 16.9 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ThiI PF02568.9 KEY66163.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.4 1 1 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) DUF4291 PF14124.1 KEY66164.1 - 2.6e-61 206.4 0.0 3e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) VPS9 PF02204.13 KEY66165.1 - 1.4e-30 105.3 0.1 2.5e-30 104.5 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 KEY66165.1 - 0.0006 19.2 0.0 0.0021 17.5 0.0 1.9 2 0 0 2 2 2 1 CUE domain TRP PF06011.7 KEY66166.1 - 3.9e-127 424.4 20.0 5e-127 424.1 13.8 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KEY66166.1 - 1.1e-40 138.9 0.3 1.7e-40 138.3 0.2 1.3 1 0 0 1 1 1 1 ML-like domain FtsL PF04999.8 KEY66166.1 - 6.2 6.6 5.7 6 6.6 0.0 3.0 2 1 1 3 3 3 0 Cell division protein FtsL Fungal_trans PF04082.13 KEY66167.1 - 1.2e-07 30.8 0.6 2.2e-07 30.0 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY66167.1 - 3.4e-07 30.0 8.6 7e-07 29.0 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 KEY66168.1 - 7.3e-26 89.0 16.8 3.9e-08 32.8 0.3 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ PF01011.16 KEY66168.1 - 0.066 12.7 0.3 35 4.1 0.0 4.0 4 0 0 4 4 4 0 PQQ enzyme repeat Glyco_transf_15 PF01793.11 KEY66169.1 - 3.9e-135 450.0 10.4 4.8e-135 449.7 7.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Spc97_Spc98 PF04130.8 KEY66170.1 - 4.7e-77 259.5 1.3 6.8e-77 259.0 0.9 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 KEY66170.1 - 2.7e-12 45.6 0.4 4.2e-12 45.0 0.3 1.2 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Abhydrolase_2 PF02230.11 KEY66171.1 - 1.5e-10 40.8 0.0 2.8e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KEY66171.1 - 1.7e-05 24.6 0.0 2.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY66171.1 - 2.3e-05 24.3 0.6 2.9e-05 24.0 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCCL PF03815.14 KEY66172.1 - 5.3e-20 71.2 0.2 1e-19 70.3 0.1 1.4 1 0 0 1 1 1 1 LCCL domain DUF3087 PF11286.3 KEY66172.1 - 6.2 6.0 5.4 8.2 5.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) TGT PF01702.13 KEY66173.1 - 3.3e-35 121.5 0.0 4.4e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Alk_phosphatase PF00245.15 KEY66174.1 - 5.2e-60 203.2 0.5 1e-55 189.1 0.0 2.8 2 1 0 2 2 2 2 Alkaline phosphatase Phosphodiest PF01663.17 KEY66174.1 - 2.5e-06 27.0 0.0 5.3e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KEY66174.1 - 1.6e-05 24.2 0.1 3.9e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 KEY66174.1 - 0.0069 14.8 0.1 0.029 12.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF1501 PF07394.7 KEY66174.1 - 0.022 13.6 0.2 0.033 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) PAS_9 PF13426.1 KEY66174.1 - 0.038 14.3 0.0 0.079 13.3 0.0 1.5 1 0 0 1 1 1 0 PAS domain CutC PF03932.9 KEY66175.1 - 4.5e-31 107.6 0.0 9.8e-31 106.5 0.0 1.5 1 1 0 1 1 1 1 CutC family NAP PF00956.13 KEY66176.1 - 1.2e-45 155.5 10.8 2.4e-45 154.5 7.5 1.4 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) FLO_LFY PF01698.11 KEY66176.1 - 0.05 12.4 2.1 0.084 11.7 1.5 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein PSII_BNR PF14870.1 KEY66177.1 - 1.8e-09 37.0 4.1 5.1e-07 28.9 0.0 3.8 2 2 2 4 4 4 2 Photosynthesis system II assembly factor YCF48 BNR PF02012.15 KEY66177.1 - 1.7e-06 26.9 29.1 0.1 12.4 0.4 6.4 6 0 0 6 6 6 5 BNR/Asp-box repeat BNR_2 PF13088.1 KEY66177.1 - 0.00015 21.1 5.6 0.98 8.6 0.3 4.2 2 2 1 3 3 3 3 BNR repeat-like domain Mo-co_dimer PF03404.11 KEY66177.1 - 2.6 7.6 8.0 38 3.9 0.0 4.6 4 1 0 5 5 5 0 Mo-co oxidoreductase dimerisation domain DUF4243 PF14027.1 KEY66179.1 - 1.9e-84 283.9 2.3 2.3e-84 283.6 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) WD40 PF00400.27 KEY66180.1 - 2.4e-52 173.0 30.7 1.6e-11 43.5 0.0 13.0 13 0 0 13 13 13 10 WD domain, G-beta repeat Utp12 PF04003.7 KEY66180.1 - 3.8e-26 91.1 0.0 6.1e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 KEY66180.1 - 6.6e-07 29.2 2.6 0.044 13.4 0.0 5.9 7 1 1 8 8 8 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KEY66180.1 - 0.00062 18.0 4.6 0.068 11.2 0.0 3.9 2 1 0 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 KEY66180.1 - 0.01 14.9 0.1 4.2 6.3 0.0 3.1 3 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 KEY66180.1 - 0.027 12.7 0.1 2.1 6.5 0.0 3.1 2 1 1 3 3 3 0 Cytochrome D1 heme domain Septin PF00735.13 KEY66181.1 - 1.7e-110 368.4 0.2 2.7e-110 367.8 0.1 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KEY66181.1 - 5.7e-07 29.4 0.0 1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEY66181.1 - 2.2e-06 27.2 0.0 7.1e-05 22.3 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KEY66181.1 - 9e-06 24.9 0.3 2.2e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 KEY66181.1 - 0.0024 18.3 0.1 0.0079 16.6 0.1 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 KEY66181.1 - 0.0031 17.1 0.1 0.0065 16.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEY66181.1 - 0.0047 17.0 0.6 0.011 15.8 0.0 1.9 2 2 0 2 2 2 1 AAA domain AIG1 PF04548.11 KEY66181.1 - 0.0061 15.6 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.13 KEY66181.1 - 0.0069 15.8 0.1 0.025 14.0 0.0 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 KEY66181.1 - 0.0089 15.8 7.2 0.47 10.2 0.1 3.3 2 1 1 3 3 3 1 Dynamin family IIGP PF05049.8 KEY66181.1 - 0.012 14.4 0.0 0.022 13.5 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 KEY66181.1 - 0.016 15.4 0.3 0.071 13.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Ras PF00071.17 KEY66181.1 - 0.017 14.5 0.5 0.053 12.9 0.4 1.8 1 1 0 1 1 1 0 Ras family Pox_A32 PF04665.7 KEY66181.1 - 0.019 14.2 0.1 0.033 13.4 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_16 PF13191.1 KEY66181.1 - 0.02 14.8 0.7 0.26 11.2 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain DUF2968 PF11180.3 KEY66181.1 - 0.033 13.5 4.3 0.099 12.0 3.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) NACHT PF05729.7 KEY66181.1 - 0.037 13.7 0.0 0.075 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain T2SE PF00437.15 KEY66181.1 - 0.044 12.6 0.3 0.15 10.9 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein KAP_NTPase PF07693.9 KEY66181.1 - 0.055 12.4 2.1 0.1 11.5 1.5 1.6 1 1 0 1 1 1 0 KAP family P-loop domain PduV-EutP PF10662.4 KEY66181.1 - 0.063 12.7 0.3 2.7 7.4 0.2 2.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF3891 PF13030.1 KEY66181.1 - 0.082 12.3 2.5 0.32 10.4 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3891) RNA_helicase PF00910.17 KEY66181.1 - 0.11 12.6 0.0 0.35 11.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.12 KEY66181.1 - 0.12 11.8 1.3 8.9 5.7 0.1 2.8 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein PRK PF00485.13 KEY66181.1 - 0.18 11.3 2.1 0.45 10.0 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Ribosomal_L6e PF01159.14 KEY66181.1 - 0.24 11.6 6.2 4 7.7 0.1 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e Myc-LZ PF02344.10 KEY66181.1 - 0.58 9.8 8.8 0.2 11.3 1.4 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain ArgK PF03308.11 KEY66181.1 - 0.84 8.3 3.5 5.4 5.7 0.0 2.7 3 0 0 3 3 3 0 ArgK protein AAA_23 PF13476.1 KEY66181.1 - 4.7 7.4 18.7 99 3.1 13.0 2.1 1 1 0 1 1 1 0 AAA domain BCDHK_Adom3 PF10436.4 KEY66182.1 - 2.5e-42 144.1 0.4 4.6e-42 143.3 0.1 1.6 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KEY66182.1 - 4.7e-12 45.6 0.0 1.6e-10 40.6 0.0 2.8 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KEY66182.1 - 0.00016 21.3 0.0 0.0003 20.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase USP7_ICP0_bdg PF12436.3 KEY66183.1 - 1.6e-80 269.9 0.0 7.3e-79 264.5 0.0 2.8 2 1 1 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 KEY66183.1 - 2.6e-76 255.7 7.1 1e-74 250.5 0.9 4.1 4 1 1 5 5 5 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 KEY66183.1 - 1.9e-56 191.1 1.0 3.2e-56 190.4 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEY66183.1 - 1e-28 100.6 0.0 1.8e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KEY66183.1 - 1.1e-11 45.0 0.5 5.7e-11 42.7 0.0 2.5 2 0 0 2 2 2 1 MATH domain YukD PF08817.5 KEY66183.1 - 1.7e-06 28.4 0.0 0.071 13.6 0.0 3.5 3 0 0 3 3 3 2 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD PF11976.3 KEY66183.1 - 0.027 14.1 0.1 35 4.1 0.0 3.9 4 0 0 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like SLBB PF10531.4 KEY66183.1 - 0.075 12.9 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 SLBB domain Asparaginase PF00710.15 KEY66184.1 - 4.5e-105 350.9 0.0 6.4e-105 350.4 0.0 1.2 1 0 0 1 1 1 1 Asparaginase Ank PF00023.25 KEY66184.1 - 6.8e-17 60.3 0.0 1.2e-07 31.1 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 KEY66184.1 - 9.8e-16 57.8 0.1 4e-15 55.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEY66184.1 - 4.9e-12 46.0 0.2 3.9e-08 33.5 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY66184.1 - 1.1e-10 40.6 0.0 0.0001 22.2 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KEY66184.1 - 1.6e-09 37.6 0.0 2e-05 24.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Pkinase PF00069.20 KEY66185.1 - 1.6e-65 220.8 0.0 1.9e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY66185.1 - 1.1e-30 106.6 0.0 1.3e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY66185.1 - 0.00048 19.1 0.0 0.0009 18.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like IncA PF04156.9 KEY66186.1 - 0.65 9.5 5.0 1.3 8.5 3.5 1.5 1 0 0 1 1 1 0 IncA protein AMPKBI PF04739.10 KEY66187.1 - 2.6e-30 104.2 0.8 2.6e-30 104.2 0.5 2.3 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Peptidase_M22 PF00814.20 KEY66188.1 - 3e-85 285.9 0.1 3.8e-85 285.6 0.1 1.0 1 0 0 1 1 1 1 Glycoprotease family EPL1 PF10513.4 KEY66189.1 - 6e-26 91.5 1.1 6e-26 91.5 0.8 3.1 3 1 0 3 3 3 1 Enhancer of polycomb-like EF-hand_1 PF00036.27 KEY66190.1 - 5.6e-26 87.8 13.5 5.7e-07 28.3 0.6 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KEY66190.1 - 3.3e-23 81.5 3.8 1.5e-12 47.4 0.6 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEY66190.1 - 9.5e-20 68.6 6.1 7.3e-05 22.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KEY66190.1 - 3.1e-18 64.1 13.3 2.5e-06 26.5 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KEY66190.1 - 2.8e-14 52.4 14.9 2.7e-05 23.6 0.8 4.6 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KEY66190.1 - 1.3e-06 28.3 0.0 0.00035 20.5 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KEY66190.1 - 6.8e-06 25.7 8.1 0.0023 17.6 0.4 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KEY66190.1 - 0.033 14.1 0.2 2.1 8.3 0.0 3.0 2 1 1 3 3 3 0 EF-hand domain Ribosomal_S9 PF00380.14 KEY66192.1 - 1.3e-34 118.9 1.1 2e-34 118.4 0.4 1.6 2 0 0 2 2 2 1 Ribosomal protein S9/S16 EF1G PF00647.14 KEY66193.1 - 1.4e-41 140.5 0.0 3.2e-41 139.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 KEY66193.1 - 1.4e-15 56.9 0.1 4.2e-15 55.5 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KEY66193.1 - 2.1e-11 43.5 0.2 1.1e-10 41.1 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KEY66193.1 - 3.5e-07 30.3 0.0 1.5e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KEY66193.1 - 7.5e-06 26.3 0.1 1.5e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KEY66193.1 - 5.1e-05 23.4 0.0 0.00013 22.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NIF PF03031.13 KEY66194.1 - 1.1e-18 67.4 0.1 1.8e-18 66.6 0.0 1.4 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase DUF947 PF06102.7 KEY66195.1 - 8.8e-53 178.5 21.2 1.4e-52 177.8 14.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF947) ABC1 PF03109.11 KEY66196.1 - 1e-31 109.3 0.0 2.2e-31 108.3 0.0 1.6 1 0 0 1 1 1 1 ABC1 family NADHdh_A3 PF14987.1 KEY66196.1 - 0.063 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Pkinase PF00069.20 KEY66196.1 - 0.088 11.9 0.0 0.53 9.3 0.0 2.0 1 1 0 1 1 1 0 Protein kinase domain Es2 PF09751.4 KEY66197.1 - 2.1e-97 327.2 2.7 3.1e-97 326.6 1.9 1.3 1 0 0 1 1 1 1 Nuclear protein Es2 Metallophos PF00149.23 KEY66198.1 - 1.1e-40 139.1 0.1 1.7e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 KEY66198.1 - 2e-32 111.0 1.0 6e-32 109.5 0.7 1.8 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 KEY66198.1 - 7.8e-24 83.1 4.2 7.8e-16 57.4 0.1 2.4 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 KEY66198.1 - 4.1e-18 64.1 0.2 0.00011 21.6 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEY66198.1 - 2.5e-13 48.8 0.1 0.0081 16.0 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEY66198.1 - 3.4e-06 26.8 1.1 0.066 13.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEY66198.1 - 0.00016 21.4 0.0 0.0035 17.1 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEY66198.1 - 0.00026 21.5 0.0 0.052 14.2 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEY66198.1 - 0.00063 20.1 0.0 1.5 9.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEY66198.1 - 0.0035 17.2 0.1 0.033 14.1 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEY66198.1 - 0.0089 15.7 0.1 16 5.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KEY66198.1 - 0.01 15.9 0.3 0.024 14.7 0.2 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KEY66198.1 - 0.023 15.0 0.0 1.7 9.0 0.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat Spt4 PF06093.8 KEY66200.1 - 3.1e-32 110.2 0.2 3.8e-32 109.9 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RNHCP PF12647.2 KEY66200.1 - 0.07 12.9 0.3 0.091 12.5 0.2 1.2 1 0 0 1 1 1 0 RNHCP domain TBCC PF07986.7 KEY66200.1 - 0.1 11.9 0.7 0.13 11.6 0.5 1.2 1 0 0 1 1 1 0 Tubulin binding cofactor C BH3 PF15285.1 KEY66200.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting Kin17_mid PF10357.4 KEY66201.1 - 8.8e-50 167.5 0.9 8.8e-50 167.5 0.7 2.1 3 0 0 3 3 3 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 KEY66201.1 - 3.4e-05 23.8 2.9 7.4e-05 22.7 2.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEY66201.1 - 5.7e-05 23.1 3.9 0.00012 22.1 2.7 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KEY66201.1 - 0.0015 18.5 0.4 0.0015 18.5 0.3 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Baculo_p74 PF04583.7 KEY66201.1 - 0.071 12.3 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Baculoviridae p74 conserved region Ecl1 PF12855.2 KEY66201.1 - 0.075 12.3 0.4 0.19 11.0 0.2 1.6 1 0 0 1 1 1 0 Life-span regulatory factor Menin PF05053.8 KEY66201.1 - 0.099 10.7 4.3 0.12 10.5 3.0 1.1 1 0 0 1 1 1 0 Menin DUF572 PF04502.8 KEY66202.1 - 5.1e-74 249.3 11.4 6.2e-74 249.1 7.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Benyvirus_14KDa PF07255.6 KEY66202.1 - 0.0036 17.1 0.0 0.0074 16.1 0.0 1.5 1 0 0 1 1 1 1 Benyvirus 14KDa protein zf-FCS PF06467.9 KEY66202.1 - 0.094 12.3 0.6 3.1 7.5 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Lar_restr_allev PF14354.1 KEY66202.1 - 0.37 11.1 2.0 12 6.2 0.0 2.9 2 1 1 3 3 3 0 Restriction alleviation protein Lar DUF951 PF06107.6 KEY66202.1 - 0.77 9.3 4.6 5.3 6.6 0.0 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF951) HTH_psq PF05225.11 KEY66205.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 KEY66205.1 - 0.023 14.4 0.0 0.067 13.0 0.0 1.8 1 1 0 1 1 1 0 Tc5 transposase DNA-binding domain Arrestin_N PF00339.24 KEY66206.1 - 3.7e-12 46.2 0.0 1.1e-11 44.7 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KEY66206.1 - 6.6e-12 45.7 0.0 1.9e-11 44.1 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 KEY66206.1 - 0.0014 18.1 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like PH PF00169.24 KEY66207.1 - 0.00031 20.9 0.0 0.00059 20.0 0.0 1.5 1 0 0 1 1 1 1 PH domain Apolipoprotein PF01442.13 KEY66207.1 - 0.0025 17.3 1.0 0.0081 15.6 0.6 1.9 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain PilJ PF13675.1 KEY66207.1 - 0.062 13.6 0.5 1.7 8.9 0.1 2.7 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Smac_DIABLO PF09057.5 KEY66207.1 - 0.11 11.5 0.4 0.22 10.5 0.3 1.4 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases eRF1_3 PF03465.10 KEY66207.1 - 0.12 12.6 0.2 0.41 10.9 0.0 2.0 3 0 0 3 3 3 0 eRF1 domain 3 DUF2383 PF09537.5 KEY66207.1 - 0.92 9.7 4.4 8.3 6.7 0.1 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF2383) MFS_1 PF07690.11 KEY66208.1 - 1.1e-37 129.5 27.8 6.6e-28 97.4 4.5 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY66208.1 - 3.6e-12 45.6 2.9 3.6e-12 45.6 2.0 3.4 3 1 0 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.8 KEY66208.1 - 0.0001 20.6 2.5 0.00017 19.9 1.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GFO_IDH_MocA PF01408.17 KEY66209.1 - 1.6e-22 80.2 0.1 2.8e-22 79.4 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KEY66209.1 - 1.4e-06 28.0 0.0 3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.12 KEY66209.1 - 0.0066 16.8 0.1 0.012 16.0 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent HET PF06985.6 KEY66210.1 - 2.7e-28 98.8 0.8 2.3e-23 82.8 0.3 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 KEY66210.1 - 8.7e-16 58.0 0.0 1.7e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEY66210.1 - 1.4e-12 47.3 1.2 4.3e-10 39.4 0.4 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEY66210.1 - 1.5e-11 44.5 1.7 3.5e-10 40.1 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.25 KEY66210.1 - 6.7e-11 41.4 1.0 0.00064 19.4 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KEY66210.1 - 3.4e-08 32.9 0.0 0.0082 16.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Cas_Csm6 PF09659.5 KEY66210.1 - 0.0015 17.2 0.0 0.0023 16.6 0.0 1.2 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csm6) GST_C_3 PF14497.1 KEY66212.1 - 1.2e-07 32.0 0.0 1.9e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KEY66212.1 - 0.019 15.1 0.0 0.14 12.3 0.0 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEY66212.1 - 0.062 13.1 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HET PF06985.6 KEY66213.1 - 4.9e-18 65.6 0.0 3.3e-17 62.9 0.0 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NPP1 PF05630.6 KEY66215.1 - 5.2e-64 215.8 0.0 6e-64 215.5 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) COesterase PF00135.23 KEY66216.1 - 1.6e-77 261.4 0.0 1.4e-71 241.8 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KEY66216.1 - 9e-07 28.6 0.1 1.9e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold He_PIG PF05345.7 KEY66216.1 - 0.014 15.4 0.6 0.061 13.3 0.4 2.1 1 0 0 1 1 1 0 Putative Ig domain ADH_zinc_N PF00107.21 KEY66217.1 - 7.7e-09 35.1 0.3 1.4e-08 34.3 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY66217.1 - 0.0011 18.6 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF4066 PF13278.1 KEY66218.1 - 1.8e-20 72.8 0.0 2.2e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KEY66218.1 - 3.3e-10 39.5 0.0 4.5e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family zf-C2H2_jaz PF12171.3 KEY66219.1 - 0.00034 20.6 0.8 0.017 15.2 0.0 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KEY66219.1 - 0.00055 19.9 4.5 0.00085 19.3 3.2 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 KEY66219.1 - 0.01 15.9 0.1 0.01 15.9 0.0 2.6 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-RING_3 PF14369.1 KEY66219.1 - 0.13 12.2 2.2 0.16 12.0 0.1 2.2 2 0 0 2 2 2 0 zinc-finger zf-met PF12874.2 KEY66219.1 - 0.16 12.2 4.8 0.36 11.1 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KEY66219.1 - 0.83 10.1 11.5 4.2 7.9 0.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger PT PF04886.7 KEY66220.1 - 0.034 13.4 0.0 0.034 13.4 0.0 3.9 4 0 0 4 4 4 0 PT repeat Methyltransf_14 PF08484.6 KEY66222.1 - 0.056 13.0 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 C-methyltransferase C-terminal domain UPF0261 PF06792.6 KEY66223.1 - 6.3e-149 495.8 0.3 7.5e-149 495.5 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) PrpR_N PF06506.6 KEY66223.1 - 0.096 12.0 0.1 13 5.1 0.0 2.4 2 0 0 2 2 2 0 Propionate catabolism activator TIM-br_sig_trns PF09370.5 KEY66224.1 - 2.6e-137 456.2 0.3 2.9e-137 456.0 0.2 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 KEY66224.1 - 3.9e-05 22.9 0.2 5.8e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase GFO_IDH_MocA PF01408.17 KEY66225.1 - 2.8e-18 66.5 0.1 6.6e-18 65.3 0.1 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 KEY66225.1 - 1e-05 25.4 0.1 0.00047 20.0 0.0 2.5 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 KEY66225.1 - 0.0041 17.4 0.2 0.024 14.9 0.0 2.1 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 KEY66225.1 - 0.0099 16.2 0.1 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Zn_clus PF00172.13 KEY66226.1 - 8.7e-06 25.5 6.1 1.7e-05 24.5 4.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PMEI PF04043.10 KEY66227.1 - 0.011 15.6 0.8 0.02 14.8 0.5 1.4 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor 4HB_MCP_1 PF12729.2 KEY66227.1 - 0.048 13.0 13.5 0.017 14.4 0.6 3.5 4 0 0 4 4 4 0 Four helix bundle sensory module for signal transduction BTB PF00651.26 KEY66228.1 - 2e-15 56.7 0.0 5.3e-14 52.1 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain Sif PF06767.6 KEY66228.1 - 0.012 14.4 0.2 0.028 13.2 0.1 1.4 1 1 0 1 1 1 0 Sif protein BACK PF07707.10 KEY66228.1 - 0.031 14.0 1.4 2.2 8.1 0.1 2.6 1 1 1 2 2 2 0 BTB And C-terminal Kelch Connexin_CCC PF10582.4 KEY66228.1 - 0.24 11.2 2.2 4.8 7.0 0.1 2.7 3 0 0 3 3 3 0 Gap junction channel protein cysteine-rich domain Pribosyltran PF00156.22 KEY66229.1 - 1.5e-17 63.4 0.1 2.8e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_4 PF01565.18 KEY66229.1 - 4.1e-13 48.9 4.3 8.7e-13 47.9 2.5 1.9 2 0 0 2 2 2 1 FAD binding domain P-mevalo_kinase PF04275.9 KEY66229.1 - 2.7e-09 36.7 0.0 5.8e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Phosphomevalonate kinase UPRTase PF14681.1 KEY66229.1 - 0.0012 18.0 0.0 0.0024 17.1 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Methyltransf_23 PF13489.1 KEY66229.1 - 0.0023 17.6 0.0 0.0061 16.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain BBE PF08031.7 KEY66229.1 - 0.0044 16.9 0.1 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like PRTase_2 PF15609.1 KEY66229.1 - 0.015 14.5 0.0 0.043 13.1 0.0 1.7 2 0 0 2 2 2 0 Phosphoribosyl transferase GTP_cyclohydroI PF01227.17 KEY66230.1 - 3.1e-50 169.9 0.0 7.7e-39 132.8 0.0 2.2 1 1 1 2 2 2 2 GTP cyclohydrolase I DUF2075 PF09848.4 KEY66231.1 - 4.9e-69 232.9 0.0 6.9e-69 232.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Hydrolase_6 PF13344.1 KEY66231.1 - 5.4e-25 87.2 0.0 1.9e-24 85.4 0.0 2.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEY66231.1 - 8.9e-14 50.9 0.1 4.1e-13 48.8 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like AAA_19 PF13245.1 KEY66231.1 - 6e-05 22.7 0.0 0.00064 19.4 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain MazG-like PF12643.2 KEY66231.1 - 0.00049 19.9 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 MazG-like family AAA_22 PF13401.1 KEY66231.1 - 0.0011 19.1 0.0 0.0051 16.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain MazG PF03819.12 KEY66231.1 - 0.0011 18.8 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain GIY-YIG PF01541.19 KEY66231.1 - 0.0015 18.8 0.0 0.0035 17.6 0.0 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain HAD_2 PF13419.1 KEY66231.1 - 0.0043 17.2 0.1 0.92 9.6 0.0 4.0 3 2 1 4 4 4 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEY66231.1 - 0.0065 16.9 0.0 0.13 12.6 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DEAD PF00270.24 KEY66231.1 - 0.0089 15.5 0.1 0.092 12.2 0.1 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.1 KEY66231.1 - 0.0098 15.8 1.2 0.04 13.9 0.2 2.5 3 1 0 3 3 3 1 AAA ATPase domain Zot PF05707.7 KEY66231.1 - 0.028 13.8 0.0 0.061 12.7 0.0 1.6 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_11 PF13086.1 KEY66231.1 - 0.04 13.4 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 KEY66231.1 - 0.041 13.7 0.0 2 8.1 0.0 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit T2SE PF00437.15 KEY66231.1 - 0.16 10.8 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Pectate_lyase PF03211.8 KEY66232.1 - 1.9e-61 207.1 5.9 2.8e-61 206.6 4.1 1.1 1 0 0 1 1 1 1 Pectate lyase Glyco_hydro_28 PF00295.12 KEY66233.1 - 2e-31 109.1 2.6 3.2e-31 108.5 1.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 KEY66233.1 - 0.1 12.3 19.4 0.032 13.9 7.1 2.5 1 1 1 2 2 2 0 Right handed beta helix region Glyco_hydro_12 PF01670.11 KEY66234.1 - 1.1e-50 171.4 3.5 1.1e-50 171.4 2.4 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 12 Ish1 PF10281.4 KEY66235.1 - 0.047 13.7 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Fungal_trans PF04082.13 KEY66236.1 - 2.2e-18 66.0 2.6 2.2e-18 66.0 1.8 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY66236.1 - 7.7e-08 32.1 11.8 1.3e-07 31.3 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.6 KEY66237.1 - 2.5e-19 69.8 0.1 4.6e-19 68.9 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF411 PF04214.8 KEY66237.1 - 0.043 13.3 0.0 0.43 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF HET PF06985.6 KEY66238.1 - 1.6e-35 122.2 0.0 2.5e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 KEY66239.1 - 4.7e-77 259.4 0.0 6e-77 259.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_2 PF13347.1 KEY66241.1 - 0.028 12.8 0.0 0.038 12.3 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein OSCP PF00213.13 KEY66241.1 - 0.035 13.9 0.1 0.055 13.3 0.1 1.2 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit CopD PF05425.8 KEY66241.1 - 0.081 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Copper resistance protein D Rep_fac-A_3 PF08661.6 KEY66243.1 - 8.1e-09 35.3 0.0 1.6e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Replication factor A protein 3 RhoGAP PF00620.22 KEY66244.1 - 2.9e-08 33.4 0.0 6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Bap31 PF05529.7 KEY66244.1 - 0.095 12.1 1.2 0.2 11.1 0.9 1.5 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like FUSC PF04632.7 KEY66244.1 - 0.75 8.1 17.5 0.01 14.3 6.6 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family CBS PF00571.23 KEY66245.1 - 1.6e-33 114.1 6.1 1.7e-13 50.0 0.2 4.3 4 0 0 4 4 4 4 CBS domain Arm PF00514.18 KEY66246.1 - 4e-72 235.8 33.3 1.5e-13 50.0 0.1 11.0 11 0 0 11 11 11 10 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KEY66246.1 - 2.7e-24 85.2 11.3 1.5e-07 31.5 0.2 7.4 2 2 2 5 5 5 5 HEAT repeats HEAT PF02985.17 KEY66246.1 - 2e-19 67.8 16.5 0.016 15.2 0.0 9.6 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 KEY66246.1 - 1e-16 60.8 11.9 0.0017 18.7 0.1 8.5 6 1 3 9 9 9 5 HEAT-like repeat Adaptin_N PF01602.15 KEY66246.1 - 1e-12 47.2 7.4 3.2e-07 29.0 0.2 2.7 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 KEY66246.1 - 2.3e-11 43.2 7.7 0.00073 18.7 0.5 3.3 2 1 1 3 3 3 3 Armadillo-like KAP PF05804.7 KEY66246.1 - 1.9e-09 36.0 0.6 3.8e-09 35.0 0.4 1.5 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 KEY66246.1 - 2.9e-09 36.4 1.4 2.2e-05 23.7 0.5 3.4 2 1 1 3 3 3 2 V-ATPase subunit H DUF908 PF06012.7 KEY66246.1 - 0.0016 17.8 4.6 0.69 9.1 0.1 4.0 3 1 2 5 5 5 2 Domain of Unknown Function (DUF908) HEAT_PBS PF03130.11 KEY66246.1 - 0.0021 18.3 4.8 32 5.3 0.1 6.8 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat DUF2454 PF10521.4 KEY66246.1 - 0.003 16.6 0.6 0.023 13.7 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2454) PUL PF08324.6 KEY66246.1 - 0.015 14.1 0.3 0.057 12.1 0.2 2.0 1 0 0 1 1 1 0 PUL domain Vac14_Fab1_bd PF12755.2 KEY66246.1 - 0.034 14.5 0.1 4.7 7.6 0.0 3.5 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region Peptidase_S24 PF00717.18 KEY66247.1 - 2.3e-05 23.9 0.1 4.8e-05 22.9 0.1 1.5 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.4 KEY66247.1 - 0.062 12.8 0.0 1.9 8.0 0.0 2.4 2 1 0 2 2 2 0 Signal peptidase, peptidase S26 IF3_C PF00707.17 KEY66248.1 - 5.1e-11 42.1 0.7 7.7e-11 41.5 0.5 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 KEY66248.1 - 2.9e-05 23.5 1.9 2.9e-05 23.5 0.8 1.4 1 1 0 1 1 1 1 Mitochondrial translation initiation factor Alb1 PF09135.6 KEY66249.1 - 2.3e-22 79.7 13.3 3.1e-22 79.2 9.2 1.2 1 0 0 1 1 1 1 Alb1 PEPCK_ATP PF01293.15 KEY66249.1 - 0.22 9.9 0.9 0.27 9.7 0.6 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase COPI_C PF06957.6 KEY66249.1 - 0.53 8.7 2.9 0.58 8.6 2.0 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Amidase PF01425.16 KEY66250.1 - 1.7e-12 46.9 0.0 6.9e-12 44.9 0.0 1.8 2 0 0 2 2 2 1 Amidase 2-Hacid_dh_C PF02826.14 KEY66251.1 - 4.7e-33 113.8 0.0 6.8e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KEY66251.1 - 1e-11 44.4 0.0 1.3e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KEY66251.1 - 0.032 14.0 0.0 0.099 12.4 0.0 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase KAT11 PF08214.6 KEY66252.1 - 4.4e-90 302.2 0.0 6.4e-90 301.7 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein Ribonucleas_3_3 PF14622.1 KEY66253.1 - 2.3e-21 76.0 0.0 4.5e-21 75.1 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like CorA PF01544.13 KEY66257.1 - 4.6e-11 42.2 1.5 4.6e-11 42.2 1.0 2.1 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Abhydrolase_6 PF12697.2 KEY66257.1 - 0.00011 22.2 1.2 0.00043 20.2 0.8 2.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KEY66257.1 - 0.00029 20.1 0.0 0.00053 19.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Ribosomal_L27 PF01016.14 KEY66259.1 - 1.2e-23 82.7 0.0 2.5e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal L27 protein DUF2076 PF09849.4 KEY66260.1 - 0.0037 17.3 0.1 0.0038 17.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF2169 PF09937.4 KEY66260.1 - 0.087 11.8 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2169) DUF2218 PF09981.4 KEY66260.1 - 0.12 12.6 0.1 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) IPP-2 PF04979.9 KEY66261.1 - 4e-13 49.7 5.3 1.8e-06 28.2 0.3 2.3 2 0 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) Zn_clus PF00172.13 KEY66262.1 - 7e-16 57.8 25.1 4.1e-08 32.9 6.7 2.9 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY66262.1 - 1.2e-12 47.3 3.1 1.7e-12 46.7 2.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain E1-E2_ATPase PF00122.15 KEY66263.1 - 9.6e-61 204.7 3.1 9.6e-61 204.7 2.1 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEY66263.1 - 2e-34 118.7 7.3 2e-34 118.7 5.0 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEY66263.1 - 7.6e-31 108.1 0.0 1.3e-29 104.2 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEY66263.1 - 1.1e-16 59.9 1.1 2.1e-16 59.1 0.1 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KEY66263.1 - 5.2e-16 58.3 0.0 1.1e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEY66263.1 - 4.4e-14 53.1 0.0 8.6e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEY66263.1 - 0.00072 19.1 0.2 0.0021 17.7 0.2 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase adh_short PF00106.20 KEY66265.1 - 8.8e-15 55.0 1.0 9.8e-15 54.8 0.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY66265.1 - 1.9e-06 27.6 0.3 2.4e-06 27.3 0.2 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KEY66265.1 - 0.00029 20.9 1.7 0.0004 20.4 1.2 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEY66265.1 - 0.0013 18.1 0.1 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KEY66265.1 - 0.0067 16.2 0.0 0.0076 16.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.21 KEY66265.1 - 0.024 14.1 0.2 0.032 13.7 0.2 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 KEY66265.1 - 0.03 14.1 4.3 0.3 10.9 0.3 2.4 1 1 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 KEY66266.1 - 5.2e-40 137.1 0.0 6e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY66266.1 - 1.2e-07 31.9 0.0 1.7e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEY66266.1 - 2.7e-06 26.2 0.0 3.7e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KEY66266.1 - 0.00064 19.2 0.1 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Acid_PPase PF12689.2 KEY66267.1 - 2.6e-61 206.1 0.0 3.2e-61 205.8 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 KEY66267.1 - 0.00073 19.8 0.7 0.0042 17.3 0.0 2.1 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase UPF0121 PF03661.8 KEY66268.1 - 1.7e-09 37.2 2.0 2.2e-09 36.8 1.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DSPc PF00782.15 KEY66269.1 - 7e-11 41.8 0.0 1.4e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEY66269.1 - 0.0051 16.1 0.0 0.009 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KEY66269.1 - 0.035 14.3 0.0 0.068 13.4 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PTEN_C2 PF10409.4 KEY66269.1 - 0.2 11.3 0.0 0.38 10.4 0.0 1.4 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Zn_clus PF00172.13 KEY66270.1 - 7.9e-05 22.4 15.5 0.00013 21.8 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEY66270.1 - 0.043 12.4 0.0 0.091 11.3 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain OB_NTP_bind PF07717.11 KEY66271.1 - 7.3e-29 99.9 0.0 2.5e-28 98.2 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KEY66271.1 - 1e-28 99.3 0.1 3.5e-28 97.5 0.1 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KEY66271.1 - 4.6e-12 45.6 0.0 1.1e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 KEY66271.1 - 4e-09 36.4 0.1 8.5e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 KEY66271.1 - 1.8e-06 27.5 0.1 4.1e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEY66271.1 - 1.1e-05 25.5 0.0 2.7e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KEY66271.1 - 1.2e-05 24.4 0.1 3.9e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 KEY66271.1 - 0.00034 20.2 0.0 0.0043 16.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEY66271.1 - 0.0026 17.4 0.1 0.0089 15.7 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KEY66271.1 - 0.019 14.8 0.1 0.2 11.5 0.1 2.5 2 1 0 2 2 1 0 AAA domain Myosin_head PF00063.16 KEY66271.1 - 0.028 12.4 0.0 0.046 11.7 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) NB-ARC PF00931.17 KEY66271.1 - 0.04 12.7 0.0 0.07 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activ_2 PF14532.1 KEY66271.1 - 0.046 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 KEY66271.1 - 0.054 13.7 0.2 0.31 11.3 0.1 2.3 1 1 0 1 1 1 0 ABC transporter PhoH PF02562.11 KEY66271.1 - 0.06 12.5 0.1 0.14 11.3 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.1 KEY66271.1 - 0.085 12.2 0.0 0.5 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.4 KEY66271.1 - 0.087 11.7 0.1 0.33 9.8 0.0 1.8 1 1 1 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 SRP54 PF00448.17 KEY66271.1 - 0.11 11.9 0.0 0.39 10.1 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ResIII PF04851.10 KEY66271.1 - 0.14 11.9 0.0 4.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_29 PF13555.1 KEY66271.1 - 0.14 11.6 0.0 0.35 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ank_2 PF12796.2 KEY66272.1 - 2.1e-36 124.1 0.4 1.3e-11 44.6 0.1 7.0 3 2 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEY66272.1 - 5.8e-29 99.4 2.7 1e-06 28.8 0.1 7.9 7 0 0 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEY66272.1 - 2.5e-27 94.7 5.9 1.6e-07 31.6 0.0 8.8 7 1 2 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.25 KEY66272.1 - 1.7e-25 87.5 12.8 0.00034 20.2 0.1 12.1 12 0 0 12 12 12 7 Ankyrin repeat Ank_3 PF13606.1 KEY66272.1 - 1.1e-17 62.3 5.9 0.079 13.2 0.0 11.4 12 0 0 12 12 12 4 Ankyrin repeat Cellulase PF00150.13 KEY66273.1 - 5.8e-40 137.2 0.2 9.5e-40 136.5 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.9 KEY66273.1 - 1.8e-13 50.1 0.0 1.3e-10 40.9 0.0 3.1 3 0 0 3 3 3 2 Carbohydrate binding domain X2 IBR PF01485.16 KEY66274.1 - 1.1e-12 47.6 16.4 3.2e-08 33.3 0.3 4.0 3 1 0 3 3 3 2 IBR domain zf-CCCH PF00642.19 KEY66274.1 - 3.8e-10 39.1 10.1 6.5e-05 22.5 2.8 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 KEY66274.1 - 0.00033 20.6 11.7 0.00033 20.6 8.1 5.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEY66274.1 - 0.0015 18.2 11.2 0.0015 18.2 7.7 4.5 2 1 1 3 3 3 1 Ring finger domain zf-CCCH_2 PF14608.1 KEY66274.1 - 0.002 18.0 19.4 0.023 14.6 2.9 3.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type zf-C3HC4_4 PF15227.1 KEY66274.1 - 0.0078 16.0 10.4 0.0078 16.0 7.2 3.6 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KEY66274.1 - 0.01 15.4 12.2 0.01 15.4 8.4 3.7 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY66274.1 - 0.013 15.2 10.8 0.013 15.2 7.5 4.1 2 1 1 3 3 3 0 zinc-RING finger domain YhfH PF14149.1 KEY66274.1 - 0.32 10.8 8.5 0.2 11.4 3.2 2.6 2 0 0 2 2 2 0 YhfH-like protein zf-tcix PF14952.1 KEY66274.1 - 5.2 6.4 10.1 0.11 11.8 1.2 2.6 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding MFS_1 PF07690.11 KEY66275.1 - 1.8e-37 128.8 56.9 4.8e-27 94.5 20.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 KEY66276.1 - 5e-05 23.0 0.2 0.0037 17.0 0.0 3.9 3 0 0 3 3 3 1 WD domain, G-beta repeat NACHT PF05729.7 KEY66276.1 - 9.5e-05 22.1 0.0 0.00024 20.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 KEY66276.1 - 0.048 13.4 0.0 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KEY66276.1 - 0.062 13.4 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain PQQ_3 PF13570.1 KEY66276.1 - 0.11 12.8 1.3 36 4.8 0.0 3.9 4 0 0 4 4 4 0 PQQ-like domain Fructosamin_kin PF03881.9 KEY66277.1 - 1.7e-30 106.0 0.0 2.1e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KEY66277.1 - 1.4e-06 28.2 0.0 3.3e-06 27.0 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family adh_short PF00106.20 KEY66279.1 - 1.6e-09 37.8 0.0 3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY66279.1 - 6.6e-05 22.6 0.0 0.00037 20.1 0.0 2.2 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 KEY66279.1 - 0.00074 19.3 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEY66279.1 - 0.0075 15.7 0.0 0.027 13.8 0.0 1.9 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY66279.1 - 0.05 13.6 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Imm42 PF15601.1 KEY66279.1 - 0.059 12.7 1.2 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Immunity protein 42 MFS_1 PF07690.11 KEY66280.1 - 4.9e-43 147.1 40.6 2.3e-39 135.1 15.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 KEY66281.1 - 4.3e-06 26.6 0.0 7.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEY66281.1 - 0.00014 21.9 0.1 0.00027 21.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEY66281.1 - 0.015 15.0 0.0 0.036 13.8 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.1 KEY66281.1 - 0.029 14.2 0.0 0.19 11.6 0.0 2.0 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KEY66281.1 - 0.039 13.8 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 KEY66281.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_M14 PF00246.19 KEY66282.1 - 6.6e-18 65.2 0.0 8.9e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF2817 PF10994.3 KEY66282.1 - 0.0027 16.8 0.0 0.0045 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) AstE_AspA PF04952.9 KEY66282.1 - 0.033 13.0 0.4 0.091 11.6 0.0 2.0 2 1 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family RVT_3 PF13456.1 KEY66282.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like Anoctamin PF04547.7 KEY66283.1 - 9.1e-101 337.7 3.3 1.1e-100 337.4 2.3 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Glyco_hydro_10 PF00331.15 KEY66284.1 - 3.1e-81 272.8 0.0 3.5e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF2218 PF09981.4 KEY66284.1 - 0.081 13.1 0.1 12 6.1 0.0 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2218) SNF2_N PF00176.18 KEY66286.1 - 1.6e-50 171.6 0.0 2.5e-50 171.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEY66286.1 - 5.4e-11 42.1 0.0 1.1e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEY66286.1 - 9.1e-09 35.4 0.1 5.3e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 KEY66286.1 - 5e-05 22.8 4.5 0.00012 21.6 3.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 KEY66286.1 - 0.00023 20.7 0.1 0.0011 18.4 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.1 KEY66286.1 - 0.00026 20.9 7.2 0.00069 19.5 5.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEY66286.1 - 0.0012 18.5 4.8 0.0031 17.2 3.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KEY66286.1 - 0.0057 16.3 6.0 0.014 15.1 4.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KEY66286.1 - 0.018 14.7 2.0 0.055 13.2 1.4 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.3 KEY66286.1 - 0.022 14.2 3.1 0.056 12.9 2.1 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 KEY66286.1 - 0.088 12.3 2.0 0.24 10.9 1.4 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.1 KEY66286.1 - 0.21 11.5 3.6 0.54 10.1 2.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Git3 PF11710.3 KEY66288.1 - 2.2e-50 171.0 13.0 3.5e-50 170.3 9.0 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 KEY66288.1 - 1.4e-12 47.2 0.1 4.4e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 KEY66288.1 - 0.00017 20.7 0.0 0.00051 19.2 0.0 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serglycin PF04360.7 KEY66288.1 - 0.061 13.0 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Serglycin GATase PF00117.23 KEY66289.1 - 1.4e-08 34.4 0.0 1.7e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 KEY66289.1 - 0.02 14.4 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Beta-lactamase PF00144.19 KEY66290.1 - 1.5e-36 126.1 0.1 1.9e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S13 PF02113.10 KEY66290.1 - 0.036 12.5 0.1 0.056 11.9 0.0 1.2 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Peptidase_S11 PF00768.15 KEY66290.1 - 0.079 12.2 0.0 0.16 11.2 0.0 1.5 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase DHHA2 PF02833.9 KEY66291.1 - 2.2e-25 89.2 0.0 3.4e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 KEY66291.1 - 4e-09 36.2 0.0 6.5e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 DHH family Oligomerisation PF02410.10 KEY66292.1 - 1.8e-05 24.7 0.0 0.00035 20.5 0.0 2.8 2 1 0 2 2 2 1 Oligomerisation domain RNA_pol PF00940.14 KEY66293.1 - 2.1e-161 536.9 0.0 3.1e-161 536.3 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 KEY66293.1 - 9.4e-75 251.8 2.8 1.5e-74 251.1 1.9 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal tRNA_bind PF01588.15 KEY66294.1 - 9.1e-22 76.7 0.2 4.5e-21 74.5 0.1 2.1 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 KEY66294.1 - 5.6e-08 33.1 0.1 1.6e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KEY66294.1 - 6.1e-05 22.8 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KEY66294.1 - 0.00024 21.0 0.1 0.023 14.6 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Pol_alpha_B_N PF08418.5 KEY66294.1 - 0.084 12.4 4.0 0.95 8.9 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal RR_TM4-6 PF06459.7 KEY66294.1 - 2.2 8.0 8.3 3.4 7.4 5.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SNF2_N PF00176.18 KEY66295.1 - 4e-71 239.2 0.6 7.4e-71 238.3 0.1 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEY66295.1 - 6.2e-17 61.2 0.1 1.6e-16 59.8 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEY66295.1 - 8e-08 32.3 1.0 2.2e-07 30.8 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KEY66295.1 - 2.8e-05 23.0 0.0 2.8e-05 23.0 0.0 2.0 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Ank_2 PF12796.2 KEY66296.1 - 1.1e-61 205.1 20.2 1.5e-09 38.0 0.0 15.0 6 4 7 13 13 13 12 Ankyrin repeats (3 copies) Ank PF00023.25 KEY66296.1 - 7e-26 88.7 40.9 5.4e-05 22.8 0.0 21.0 23 3 1 24 24 24 8 Ankyrin repeat Ank_4 PF13637.1 KEY66296.1 - 1.6e-24 85.8 18.2 8.5e-05 22.9 0.0 15.9 15 2 2 17 17 17 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY66296.1 - 3.5e-22 76.2 11.4 0.067 13.4 0.0 18.4 20 1 1 21 21 21 2 Ankyrin repeat Ank_5 PF13857.1 KEY66296.1 - 2.4e-15 56.2 21.6 2.4e-07 30.7 0.0 12.9 14 3 3 17 17 17 3 Ankyrin repeats (many copies) Abhydrolase_6 PF12697.2 KEY66297.1 - 2.8e-34 118.9 1.1 3.3e-34 118.7 0.8 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY66297.1 - 3.4e-16 59.4 0.0 6.7e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY66297.1 - 1.7e-12 47.2 0.1 3.1e-12 46.4 0.0 1.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 KEY66297.1 - 0.025 13.3 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase ADH_zinc_N PF00107.21 KEY66298.1 - 8.2e-29 99.7 0.1 1.6e-28 98.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY66298.1 - 2.1e-16 61.0 0.2 5.4e-16 59.6 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY66298.1 - 2.8e-08 33.4 0.0 8.2e-08 31.9 0.0 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ApbA PF02558.11 KEY66298.1 - 0.049 13.0 0.1 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Epimerase PF01370.16 KEY66299.1 - 7.8e-43 146.5 0.0 1e-42 146.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KEY66299.1 - 2.7e-25 88.0 0.0 5.1e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 KEY66299.1 - 1.2e-15 56.9 0.0 5.4e-15 54.8 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KEY66299.1 - 4.1e-12 45.5 0.0 7.6e-11 41.4 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KEY66299.1 - 2.7e-11 42.8 0.0 4e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KEY66299.1 - 3.6e-11 43.2 0.0 5.7e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY66299.1 - 2.8e-08 33.6 0.0 5.7e-08 32.6 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 KEY66299.1 - 3.8e-08 32.5 0.1 1.7e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KEY66299.1 - 6.2e-08 32.8 0.0 1.3e-07 31.8 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KEY66299.1 - 0.01 15.1 0.0 0.029 13.6 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family UDPG_MGDP_dh_N PF03721.9 KEY66299.1 - 0.011 15.1 0.3 0.02 14.2 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NurA PF09376.5 KEY66299.1 - 0.063 12.7 0.1 0.13 11.7 0.0 1.5 2 0 0 2 2 2 0 NurA domain DAO PF01266.19 KEY66299.1 - 0.15 10.8 0.4 0.31 9.8 0.3 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Sad1_UNC PF07738.8 KEY66300.1 - 2.2e-05 24.2 0.0 0.00032 20.4 0.0 2.3 1 1 1 2 2 2 1 Sad1 / UNC-like C-terminal Nop14 PF04147.7 KEY66300.1 - 0.02 12.8 15.8 0.033 12.1 11.0 1.2 1 0 0 1 1 1 0 Nop14-like family DEAD PF00270.24 KEY66301.1 - 1.7e-43 148.0 0.5 7.9e-43 145.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KEY66301.1 - 1.1e-24 85.7 0.0 2.7e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KEY66301.1 - 6.9e-22 77.1 0.0 1.6e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Glyco_hydro_17 PF00332.13 KEY66302.1 - 5e-06 25.7 0.3 9.8e-06 24.8 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 DUF605 PF04652.11 KEY66302.1 - 0.89 8.8 7.5 1.2 8.4 5.2 1.1 1 0 0 1 1 1 0 Vta1 like Med3 PF11593.3 KEY66302.1 - 7.5 5.6 8.8 11 5.0 6.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal YuiB PF14068.1 KEY66303.1 - 0.038 14.2 1.7 3 8.1 0.2 2.3 2 0 0 2 2 2 0 Putative membrane protein DUF588 PF04535.7 KEY66303.1 - 0.044 13.3 3.3 0.98 8.9 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF588) AMP-binding PF00501.23 KEY66304.1 - 2.3e-78 263.4 0.0 2.3e-78 263.4 0.0 1.8 3 0 0 3 3 3 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEY66304.1 - 1.8e-05 25.5 0.0 4.3e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RGS PF00615.14 KEY66305.1 - 0.0058 16.7 0.0 0.022 14.8 0.0 1.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain Remorin_C PF03763.8 KEY66305.1 - 0.099 12.1 0.1 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Remorin, C-terminal region Methyltransf_23 PF13489.1 KEY66307.1 - 1.5e-10 41.0 0.0 2.8e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY66307.1 - 0.00057 20.4 0.0 0.0014 19.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY66307.1 - 0.086 12.4 0.0 13 5.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain NUC153 PF08159.7 KEY66308.1 - 1.1e-13 50.4 2.3 1.1e-13 50.4 1.6 3.2 3 0 0 3 3 3 2 NUC153 domain DUF2790 PF10976.3 KEY66309.1 - 0.0058 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2790) Sperm_act_pep PF08250.6 KEY66309.1 - 3.1 8.3 7.1 11 6.6 4.9 2.0 1 0 0 1 1 1 0 Sperm-activating peptides DUF2781 PF10914.3 KEY66310.1 - 1.1e-21 77.2 6.5 1.2e-21 77.0 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DUF2567 PF10821.3 KEY66310.1 - 0.01 15.3 0.1 0.014 14.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) DctQ PF04290.7 KEY66310.1 - 0.012 15.3 1.6 0.018 14.7 0.0 2.1 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Iso_dh PF00180.15 KEY66311.1 - 2.2e-71 240.6 0.0 3.6e-71 239.9 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.7 KEY66311.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA MFS_1 PF07690.11 KEY66312.1 - 8.6e-36 123.3 36.3 8.6e-36 123.3 25.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY66312.1 - 1.6e-13 50.0 7.6 1.6e-13 50.0 5.3 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Nucleoporin_C PF03177.9 KEY66313.1 - 2.2e-131 439.2 3.7 2.9e-131 438.8 2.5 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KEY66313.1 - 1.1e-90 304.4 0.0 1.6e-90 303.8 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like adh_short PF00106.20 KEY66314.1 - 2.4e-20 73.1 0.0 9e-20 71.2 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY66314.1 - 4.1e-07 30.0 0.0 5.4e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY66314.1 - 3.6e-05 23.5 0.0 6.1e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KEY66314.1 - 0.0081 15.0 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KEY66314.1 - 0.014 15.4 0.1 0.037 14.0 0.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding Erg28 PF03694.8 KEY66315.1 - 2.2e-43 146.7 0.3 2.7e-43 146.4 0.2 1.1 1 0 0 1 1 1 1 Erg28 like protein DUF1625 PF07787.7 KEY66315.1 - 0.67 9.1 3.9 1 8.5 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) GalP_UDP_transf PF01087.17 KEY66316.1 - 2.4e-68 229.8 0.2 2.9e-66 223.0 0.1 2.1 2 0 0 2 2 2 2 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 KEY66316.1 - 1.9e-57 193.4 0.0 3.7e-57 192.4 0.0 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 KEY66316.1 - 0.0015 18.9 0.0 0.0058 17.1 0.0 2.0 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 KEY66316.1 - 0.08 13.1 0.1 0.24 11.6 0.0 1.9 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding SWIRM PF04433.12 KEY66317.1 - 1.3e-13 50.8 0.0 4e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 KEY66317.1 - 1.5e-07 31.3 0.0 6.7e-07 29.2 0.0 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 KEY66317.1 - 1.4e-05 24.5 6.3 4.6e-05 22.8 1.2 2.4 2 0 0 2 2 2 1 Zinc finger, ZZ type Rhodanese PF00581.15 KEY66318.1 - 2.5e-15 56.7 0.0 4.3e-15 56.0 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain HD_3 PF13023.1 KEY66319.1 - 4.7e-46 156.5 0.0 6.1e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 HD domain WSC PF01822.14 KEY66321.1 - 1.5e-12 47.2 8.7 3.3e-12 46.1 6.0 1.6 1 0 0 1 1 1 1 WSC domain Podoplanin PF05808.6 KEY66321.1 - 1.4e-05 24.6 0.9 2.7e-05 23.7 0.7 1.4 1 0 0 1 1 1 1 Podoplanin VSP PF03302.8 KEY66321.1 - 0.00016 20.4 0.5 0.00016 20.4 0.3 1.7 2 0 0 2 2 2 1 Giardia variant-specific surface protein Syndecan PF01034.15 KEY66321.1 - 0.03 13.9 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.5 KEY66321.1 - 0.051 12.8 1.5 0.12 11.7 1.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 KEY66321.1 - 0.055 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MtrF PF09472.5 KEY66321.1 - 2 7.6 4.6 4 6.7 3.2 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Tho2 PF11262.3 KEY66322.1 - 4.1e-70 236.1 0.0 8.7e-70 235.1 0.0 1.6 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 KEY66322.1 - 4.4e-25 87.2 0.5 1.2e-24 85.8 0.1 2.0 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Abhydrolase_1 PF00561.15 KEY66324.1 - 9.6e-47 159.4 0.3 8.1e-25 87.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEY66324.1 - 5e-13 49.4 2.3 6.3e-12 45.8 1.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY66324.1 - 0.00097 18.9 0.1 0.014 15.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KEY66324.1 - 0.069 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein PI-PLC-X PF00388.14 KEY66325.1 - 2.1e-07 30.4 0.0 3.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Kelch_2 PF07646.10 KEY66326.1 - 0.0025 17.4 0.5 0.7 9.7 0.0 3.7 3 0 0 3 3 3 1 Kelch motif MLANA PF14991.1 KEY66326.1 - 0.0088 16.0 0.1 0.027 14.4 0.0 1.8 2 0 0 2 2 2 1 Protein melan-A DUF1251 PF06856.6 KEY66326.1 - 0.31 10.5 0.1 0.74 9.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1251) DUF221 PF02714.10 KEY66327.1 - 7.2e-104 347.1 31.4 3.3e-103 344.9 19.9 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KEY66327.1 - 2.7e-42 144.0 2.5 2.7e-42 144.0 1.7 2.9 5 1 2 7 7 7 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KEY66327.1 - 2.3e-31 107.5 0.5 1.6e-30 104.8 0.1 2.2 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 KEY66327.1 - 6.4e-16 58.6 0.0 1e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF4407 PF14362.1 KEY66328.1 - 4.5 6.1 9.0 7.6 5.3 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Radical_SAM PF04055.16 KEY66329.1 - 9.2e-10 38.9 0.0 1.4e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 KEY66329.1 - 7.9e-06 26.0 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KEY66329.1 - 0.001 19.0 0.1 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF1681 PF07933.9 KEY66331.1 - 2.6e-56 189.5 0.0 3.6e-56 189.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) IF-2B PF01008.12 KEY66332.1 - 9.9e-46 155.9 0.1 1.2e-45 155.7 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Methyltransf_33 PF10017.4 KEY66333.1 - 6.7e-17 61.5 0.0 1.9e-16 60.0 0.0 1.7 1 1 1 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 KEY66333.1 - 3.7e-16 59.2 0.6 3.3e-09 36.4 0.1 2.6 2 1 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 KEY66333.1 - 3.9e-07 30.4 0.0 1.2e-06 28.8 0.0 1.9 1 0 0 1 1 1 1 DinB superfamily Fungal_trans PF04082.13 KEY66334.1 - 2.3e-15 56.1 0.0 4.4e-15 55.2 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY66334.1 - 7.6e-08 32.1 6.6 1.4e-07 31.3 4.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 4HBT_2 PF13279.1 KEY66335.1 - 2.4e-18 66.7 0.0 3.7e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily GDE_N_bis PF14742.1 KEY66335.1 - 0.036 13.4 0.1 0.12 11.6 0.0 1.7 1 1 1 2 2 2 0 N-terminal domain of (some) glycogen debranching enzymes Val_tRNA-synt_C PF10458.4 KEY66335.1 - 0.23 11.5 3.0 0.29 11.2 0.6 2.2 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Senescence PF06911.7 KEY66336.1 - 2.1e-42 144.8 7.2 3.2e-42 144.2 5.0 1.3 1 0 0 1 1 1 1 Senescence-associated protein Spc97_Spc98 PF04130.8 KEY66337.1 - 1.2e-62 211.9 0.0 6.4e-62 209.5 0.0 2.0 2 1 0 2 2 2 1 Spc97 / Spc98 family MRI PF15325.1 KEY66338.1 - 6.3 7.8 10.8 10 7.1 2.5 2.8 2 0 0 2 2 2 0 Modulator of retrovirus infection SH3_1 PF00018.23 KEY66341.1 - 5.1e-12 44.9 0.3 5.1e-12 44.9 0.2 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KEY66341.1 - 2.5e-10 39.7 0.2 5.9e-10 38.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KEY66341.1 - 5.6e-10 38.5 0.0 3.4e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain Pkinase PF00069.20 KEY66342.1 - 1.4e-18 66.9 0.0 2.9e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KEY66342.1 - 0.00018 21.3 0.0 0.51 10.0 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KEY66342.1 - 0.0002 20.4 0.0 0.00043 19.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase CorA PF01544.13 KEY66343.1 - 0.33 9.9 8.1 2.6 6.9 0.3 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein RPAP2_Rtr1 PF04181.8 KEY66344.1 - 1.1e-16 60.6 0.0 1.9e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family Mit_ribos_Mrp51 PF11709.3 KEY66345.1 - 2.4e-70 237.2 0.0 2.8e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit TGT PF01702.13 KEY66346.1 - 2.7e-90 301.7 0.0 3.4e-90 301.4 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Hist_deacetyl PF00850.14 KEY66347.1 - 2.2e-60 204.5 0.1 3.2e-60 204.0 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain PHP PF02811.14 KEY66348.1 - 7.7e-12 45.3 0.0 1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 PHP domain DUF3433 PF11915.3 KEY66349.1 - 5.2e-31 106.6 10.7 2.3e-17 62.8 1.9 4.3 4 1 0 4 4 4 2 Protein of unknown function (DUF3433) Fumarate_red_C PF02300.12 KEY66349.1 - 6.1 6.7 7.0 22 4.9 0.1 3.0 3 0 0 3 3 3 0 Fumarate reductase subunit C ABC_tran PF00005.22 KEY66350.1 - 1.9e-49 167.4 0.4 1.2e-26 93.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KEY66350.1 - 2.6e-27 95.7 35.8 1.1e-17 64.1 17.0 3.2 3 1 1 4 4 4 2 ABC-2 family transporter protein AAA_21 PF13304.1 KEY66350.1 - 2.5e-21 76.9 1.9 0.0002 21.4 0.0 4.3 3 1 0 4 4 4 4 AAA domain AAA_29 PF13555.1 KEY66350.1 - 1.4e-09 37.3 4.1 7e-05 22.2 0.7 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 KEY66350.1 - 1.9e-07 30.5 3.5 0.094 11.9 0.3 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KEY66350.1 - 2.8e-07 31.0 3.8 0.014 15.7 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KEY66350.1 - 7.5e-05 21.9 0.0 0.58 9.1 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 KEY66350.1 - 0.00014 21.0 1.1 0.18 11.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KEY66350.1 - 0.00024 21.1 2.3 0.85 9.5 0.2 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_30 PF13604.1 KEY66350.1 - 0.0061 16.1 0.7 5 6.6 0.2 2.9 2 1 1 3 3 3 2 AAA domain AAA_22 PF13401.1 KEY66350.1 - 0.011 15.9 0.1 3.5 7.7 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KEY66350.1 - 0.013 14.9 0.2 4.4 6.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KEY66350.1 - 0.015 15.0 2.9 11 5.8 0.1 3.9 3 0 0 3 3 3 0 Part of AAA domain SbcCD_C PF13558.1 KEY66350.1 - 0.026 14.4 0.2 12 5.9 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 KEY66350.1 - 0.027 13.5 0.4 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 KEY66350.1 - 0.032 14.0 0.0 20 5.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 KEY66350.1 - 0.033 14.1 0.3 9.6 6.1 0.3 2.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 KEY66350.1 - 0.048 13.1 0.2 8.3 5.8 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MutS_V PF00488.16 KEY66350.1 - 0.089 12.1 0.1 9.7 5.5 0.0 2.8 2 0 0 2 2 2 0 MutS domain V AAA PF00004.24 KEY66350.1 - 0.11 12.6 0.0 21 5.3 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 KEY66350.1 - 0.13 11.7 0.3 0.72 9.2 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 KEY66350.1 - 0.28 10.5 1.5 17 4.6 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain DUF87 PF01935.12 KEY66350.1 - 0.37 10.5 1.7 14 5.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_13 PF13166.1 KEY66350.1 - 0.47 8.8 0.1 6.3 5.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 KEY66350.1 - 0.47 9.0 0.1 2.9 6.5 0.1 1.9 2 0 0 2 2 2 0 G-protein alpha subunit AIG1 PF04548.11 KEY66350.1 - 0.84 8.7 2.1 3.5 6.6 0.4 2.2 2 0 0 2 2 2 0 AIG1 family bZIP_1 PF00170.16 KEY66351.1 - 2.2e-06 27.5 2.1 2.2e-06 27.5 1.4 1.9 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 KEY66351.1 - 0.0092 15.7 4.1 0.021 14.6 2.8 1.6 1 0 0 1 1 1 1 Basic region leucine zipper PGC7_Stella PF15549.1 KEY66351.1 - 0.47 10.4 6.6 0.45 10.4 2.6 2.2 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain Hexapep PF00132.19 KEY66354.1 - 2.3e-13 49.0 7.6 1.7e-11 43.1 2.3 3.3 3 0 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KEY66354.1 - 4.9e-12 45.1 6.6 3.5e-11 42.4 2.2 2.9 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 KEY66354.1 - 8.8e-11 41.6 0.0 1.5e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase DUF87 PF01935.12 KEY66355.1 - 0.12 12.1 0.1 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 PRP38 PF03371.10 KEY66356.1 - 5e-63 211.8 0.0 6e-63 211.5 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Amidase PF01425.16 KEY66357.1 - 1.1e-108 363.9 0.1 1.5e-108 363.5 0.1 1.1 1 0 0 1 1 1 1 Amidase DUF3693 PF12472.3 KEY66357.1 - 0.092 12.3 0.3 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 Phage related protein PAD PF03068.10 KEY66357.1 - 0.22 9.9 0.0 0.34 9.2 0.0 1.2 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) SIP1 PF04938.7 KEY66358.1 - 0.0089 15.3 0.8 0.0089 15.3 0.6 2.9 3 1 0 3 3 3 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) FHA PF00498.21 KEY66359.1 - 1.2e-17 63.7 0.1 4.4e-17 61.9 0.1 2.1 1 0 0 1 1 1 1 FHA domain Fib_alpha PF08702.5 KEY66359.1 - 0.45 10.6 4.9 0.15 12.2 0.8 2.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin PF02996.12 KEY66359.1 - 0.91 9.1 10.3 0.49 10.0 0.3 2.5 2 0 0 2 2 2 0 Prefoldin subunit Ctr PF04145.10 KEY66359.1 - 3.9 7.5 5.4 2.1 8.3 0.0 2.7 3 0 0 3 3 3 0 Ctr copper transporter family Romo1 PF10247.4 KEY66360.1 - 1.8e-25 88.9 10.7 2.4e-25 88.5 7.4 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 VirB3 PF05101.8 KEY66360.1 - 0.022 14.7 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Tim17 PF02466.14 KEY66360.1 - 0.28 11.2 7.9 0.42 10.6 4.5 1.7 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Cu-oxidase_3 PF07732.10 KEY66361.1 - 2.4e-43 146.5 7.7 1.8e-40 137.3 0.5 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KEY66361.1 - 1.5e-34 119.1 0.0 4.1e-34 117.7 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KEY66361.1 - 6.8e-33 113.0 13.8 8.7e-33 112.7 1.5 3.6 3 1 0 3 3 3 2 Multicopper oxidase SIR2 PF02146.12 KEY66362.1 - 8.6e-55 185.2 0.0 1.4e-54 184.5 0.0 1.3 1 0 0 1 1 1 1 Sir2 family VIT1 PF01988.14 KEY66362.1 - 0.57 9.6 7.2 0.94 8.9 5.0 1.4 1 0 0 1 1 1 0 VIT family SNN_transmemb PF09049.5 KEY66363.1 - 0.26 10.9 0.3 0.26 10.9 0.2 1.8 2 0 0 2 2 2 0 Stannin transmembrane HET PF06985.6 KEY66364.1 - 1.9e-08 34.5 9.3 2.2e-08 34.3 0.0 3.3 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Oxidored_FMN PF00724.15 KEY66365.1 - 9e-64 215.6 0.0 1.2e-63 215.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pox_A6 PF04924.7 KEY66366.1 - 0.24 10.1 0.0 0.38 9.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A6 protein Methyltransf_23 PF13489.1 KEY66367.1 - 7.2e-14 51.8 0.0 1.1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY66367.1 - 1.3e-07 31.9 0.0 2.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY66367.1 - 1.7e-07 31.7 0.0 2.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY66367.1 - 0.00031 20.3 0.0 0.00061 19.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY66367.1 - 0.0028 17.6 0.0 0.0069 16.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY66367.1 - 0.0029 16.7 0.0 0.0036 16.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KEY66367.1 - 0.0035 17.7 0.0 0.0074 16.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 KEY66367.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase FkbM domain PCMT PF01135.14 KEY66367.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.3 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ank_2 PF12796.2 KEY66369.1 - 5.8e-80 263.7 8.5 1.3e-13 51.0 0.6 7.0 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KEY66369.1 - 3.6e-76 247.3 12.7 9.7e-08 31.4 0.1 14.1 14 0 0 14 14 14 12 Ankyrin repeat Ank_4 PF13637.1 KEY66369.1 - 2.2e-54 180.8 8.9 6.8e-09 36.0 0.3 10.8 4 3 5 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY66369.1 - 2.6e-52 169.5 12.3 1.2e-05 25.0 0.0 13.8 14 0 0 14 14 14 12 Ankyrin repeat Ank_5 PF13857.1 KEY66369.1 - 2.7e-47 157.7 17.4 2.4e-12 46.6 0.5 11.8 2 2 11 13 13 13 12 Ankyrin repeats (many copies) Pkinase PF00069.20 KEY66369.1 - 1.6e-24 86.4 0.0 2.7e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY66369.1 - 6.7e-19 67.9 0.0 1.2e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HeLo PF14479.1 KEY66370.1 - 9.8e-15 54.8 1.2 1.4e-14 54.3 0.8 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation Pectate_lyase PF03211.8 KEY66373.1 - 2.4e-09 36.9 0.0 3.2e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Pectate lyase HET PF06985.6 KEY66375.1 - 9.8e-33 113.2 0.2 2.1e-32 112.1 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_38C PF07748.8 KEY66376.1 - 1.4e-69 235.0 1.2 4e-69 233.6 0.8 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro_38 PF01074.17 KEY66376.1 - 1.4e-42 145.8 0.1 8.6e-36 123.5 0.1 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.6 KEY66376.1 - 6.3e-19 67.9 0.0 1.5e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Peptidase_S8 PF00082.17 KEY66377.1 - 3.7e-46 157.5 0.5 5.9e-46 156.8 0.3 1.3 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 KEY66377.1 - 7.5e-05 23.1 0.0 0.00062 20.1 0.0 2.3 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) PA PF02225.17 KEY66377.1 - 0.0002 21.0 0.0 0.0012 18.5 0.0 2.4 3 0 0 3 3 3 1 PA domain HMGL-like PF00682.14 KEY66377.1 - 0.051 13.2 0.2 0.08 12.5 0.1 1.3 1 0 0 1 1 1 0 HMGL-like DUF3176 PF11374.3 KEY66378.1 - 6.5e-10 38.8 0.3 2.7e-09 36.8 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Tmemb_14 PF03647.8 KEY66379.1 - 1.2e-18 67.2 3.7 1.5e-18 66.9 2.6 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C NADH_dh_m_C1 PF15088.1 KEY66379.1 - 0.021 14.3 0.1 0.54 9.7 0.0 2.3 1 1 1 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial DUF3318 PF11780.3 KEY66379.1 - 0.024 14.1 1.1 0.048 13.2 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3318) Gram_pos_anchor PF00746.16 KEY66379.1 - 0.46 10.3 12.2 0.51 10.2 0.0 4.1 4 1 0 4 4 4 0 Gram positive anchor AMP-binding PF00501.23 KEY66380.1 - 4e-99 331.8 0.1 6e-99 331.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KEY66380.1 - 5.9e-77 258.5 0.4 1.3e-76 257.4 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEY66380.1 - 9.5e-60 202.5 0.1 1.6e-59 201.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KEY66380.1 - 3.5e-57 192.9 3.2 1.1e-56 191.3 0.6 2.6 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KEY66380.1 - 3.9e-53 179.7 6.7 3.1e-52 176.8 0.7 3.2 3 0 0 3 3 3 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KEY66380.1 - 8.3e-48 162.4 0.0 3.1e-45 154.0 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein Ketoacyl-synt_C PF02801.17 KEY66380.1 - 1.3e-46 157.2 0.7 4.3e-46 155.6 0.4 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KEY66380.1 - 2.3e-26 91.8 0.3 6.6e-13 48.7 0.0 3.6 3 0 0 3 3 3 2 Phosphopantetheine attachment site Epimerase PF01370.16 KEY66380.1 - 1.8e-12 47.2 0.0 7.8e-07 28.7 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 KEY66380.1 - 3.1e-08 34.4 0.0 1e-07 32.8 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.10 KEY66380.1 - 7.7e-06 25.0 0.0 0.031 13.1 0.0 2.4 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Thiolase_N PF00108.18 KEY66380.1 - 6.5e-05 22.0 0.0 0.00013 21.0 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.14 KEY66380.1 - 0.0072 15.0 0.0 1.3 7.6 0.0 2.4 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KEY66380.1 - 0.008 16.2 0.2 0.31 11.0 0.0 2.6 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KEY66380.1 - 0.88 8.7 0.6 22 4.1 0.0 2.3 2 0 0 2 2 2 0 NmrA-like family NmrA PF05368.8 KEY66381.1 - 2.7e-20 72.6 0.0 3.8e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY66381.1 - 3.1e-07 30.5 0.0 1e-06 28.8 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 KEY66381.1 - 0.00019 21.1 0.0 0.00035 20.2 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KEY66381.1 - 0.0016 18.3 0.0 0.0059 16.5 0.0 2.0 2 1 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 KEY66381.1 - 0.051 13.0 0.0 0.39 10.1 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 KEY66381.1 - 0.12 12.7 0.0 0.32 11.4 0.0 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Arena_RNA_pol PF06317.6 KEY66381.1 - 0.15 8.6 0.0 0.19 8.2 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase PhyH PF05721.8 KEY66382.1 - 1.7e-35 123.0 0.1 2.1e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KEY66382.1 - 0.066 11.6 0.0 0.14 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) AATase PF07247.7 KEY66383.1 - 0.00051 18.7 0.2 0.0049 15.4 0.1 1.9 1 1 0 1 1 1 1 Alcohol acetyltransferase NAD_binding_10 PF13460.1 KEY66384.1 - 1.3e-23 83.9 0.2 1.8e-23 83.5 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEY66384.1 - 1.7e-05 24.4 0.0 4.5e-05 22.9 0.0 1.6 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Lipase_GDSL_2 PF13472.1 KEY66384.1 - 0.024 14.7 0.1 0.041 14.0 0.1 1.4 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family RmlD_sub_bind PF04321.12 KEY66384.1 - 0.041 12.7 0.0 0.066 12.0 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_hydro_61 PF03443.9 KEY66385.1 - 1.3e-77 260.5 0.0 1.3e-77 260.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KEY66385.1 - 3.7e-12 45.6 6.7 9.1e-12 44.4 4.6 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Alpha-amylase PF00128.19 KEY66386.1 - 5.3e-30 104.8 3.0 1e-29 103.9 2.1 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 KEY66386.1 - 4e-06 24.9 0.0 0.16 9.7 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.5 KEY66386.1 - 0.0085 15.9 0.0 0.036 13.9 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) DUF1996 PF09362.5 KEY66387.1 - 6.9e-41 140.4 0.0 9.9e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Glyco_transf_8 PF01501.15 KEY66388.1 - 4.7e-19 68.6 0.0 7.6e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_hydro_3 PF00933.16 KEY66389.1 - 1.7e-85 286.6 0.0 2.8e-85 285.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY66389.1 - 1.6e-61 207.7 0.0 9.6e-61 205.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEY66389.1 - 9e-19 67.1 0.2 3.8e-18 65.1 0.1 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 KEY66389.1 - 2.4e-05 23.9 0.0 4.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Fungal_trans PF04082.13 KEY66390.1 - 3.7e-24 85.0 0.1 5.4e-24 84.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain GFA PF04828.9 KEY66390.1 - 7.5e-06 25.8 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme FAA_hydrolase PF01557.13 KEY66391.1 - 1.2e-61 207.9 0.0 1.5e-61 207.5 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Cupin_2 PF07883.6 KEY66392.1 - 2.7e-20 71.6 0.8 3e-17 61.8 0.1 2.7 3 0 0 3 3 3 2 Cupin domain Cupin_1 PF00190.17 KEY66392.1 - 0.00048 19.5 0.0 0.95 8.8 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.7 KEY66392.1 - 0.0015 17.8 0.0 0.11 11.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 KEY66392.1 - 0.0016 18.1 0.3 0.0034 17.0 0.1 1.6 2 0 0 2 2 2 1 AraC-like ligand binding domain Sugar_tr PF00083.19 KEY66393.1 - 2.2e-85 286.9 28.8 2.5e-85 286.7 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY66393.1 - 8.7e-30 103.6 50.8 2.3e-24 85.7 17.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KEY66393.1 - 4.9e-06 25.0 1.5 4.9e-06 25.0 1.1 2.3 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KEY66393.1 - 0.063 13.0 0.1 0.063 13.0 0.1 3.7 4 0 0 4 4 4 0 MFS_1 like family FtsH_ext PF06480.10 KEY66393.1 - 0.11 12.7 0.4 5.8 7.1 0.0 2.8 2 0 0 2 2 2 0 FtsH Extracellular Rhabdo_glycop PF00974.13 KEY66393.1 - 1.2 7.3 4.5 0.8 7.8 0.3 2.1 1 1 1 2 2 2 0 Rhabdovirus spike glycoprotein FAD_binding_3 PF01494.14 KEY66394.1 - 3e-59 200.8 0.0 4.3e-59 200.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Gly_transf_sug PF04488.10 KEY66394.1 - 4.8e-05 23.6 0.0 0.00012 22.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif SKG6 PF08693.5 KEY66395.1 - 0.026 13.8 0.8 0.05 12.9 0.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4328 PF14219.1 KEY66395.1 - 0.026 13.8 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Adeno_E3_CR2 PF02439.10 KEY66395.1 - 0.14 11.7 1.9 0.29 10.7 1.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ketoacyl-synt PF00109.21 KEY66396.1 - 5.2e-74 248.9 0.1 1.2e-73 247.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KEY66396.1 - 9.4e-61 204.6 3.3 3.1e-60 202.9 2.3 2.0 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KEY66396.1 - 1.7e-58 198.4 0.0 3e-58 197.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KEY66396.1 - 1.9e-50 171.0 3.2 5e-50 169.6 1.6 2.2 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 KEY66396.1 - 5.9e-44 150.3 0.0 1.2e-43 149.3 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KEY66396.1 - 3e-38 130.3 0.4 1.5e-37 128.1 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KEY66396.1 - 1.9e-13 50.0 0.1 1.4e-12 47.2 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY66396.1 - 3.5e-06 26.7 0.0 9.8e-06 25.2 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KEY66396.1 - 5.3e-05 23.3 0.4 0.00013 22.1 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 KEY66396.1 - 0.00071 18.5 0.0 0.0013 17.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KEY66396.1 - 0.013 14.8 1.2 0.018 14.2 0.1 1.8 2 0 0 2 2 2 0 NmrA-like family NAD_binding_10 PF13460.1 KEY66396.1 - 0.02 14.9 4.4 0.27 11.2 0.3 3.3 3 0 0 3 3 3 0 NADH(P)-binding FSH1 PF03959.8 KEY66397.1 - 1.6e-21 76.7 0.0 4.6e-21 75.2 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) UPF0150 PF03681.10 KEY66397.1 - 0.061 12.9 0.0 0.2 11.2 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) ABC_tran PF00005.22 KEY66398.1 - 1.1e-63 213.6 0.0 1.5e-30 106.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEY66398.1 - 2.8e-59 200.7 28.6 1.5e-40 139.3 7.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KEY66398.1 - 9.2e-17 61.9 0.1 0.0068 16.4 0.0 4.2 2 2 0 4 4 4 4 AAA domain SMC_N PF02463.14 KEY66398.1 - 1.2e-15 57.3 2.4 0.00029 20.1 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 KEY66398.1 - 7.6e-12 44.5 0.5 0.00082 18.0 0.0 3.6 4 0 0 4 4 4 3 Predicted ATPase of the ABC class AAA_29 PF13555.1 KEY66398.1 - 1.5e-10 40.4 0.1 7.7e-05 22.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KEY66398.1 - 1.1e-08 35.8 0.0 0.0043 17.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KEY66398.1 - 1.9e-08 34.5 1.6 0.011 15.8 0.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEY66398.1 - 2.1e-08 34.3 1.4 0.00097 19.1 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KEY66398.1 - 8.4e-08 31.5 0.0 0.0076 15.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KEY66398.1 - 9.2e-08 31.7 0.1 0.011 15.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KEY66398.1 - 2.2e-07 31.4 0.1 0.029 14.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KEY66398.1 - 1.9e-06 27.5 1.3 0.035 13.8 0.0 3.7 4 0 0 4 4 3 2 Part of AAA domain MobB PF03205.9 KEY66398.1 - 6.8e-06 25.8 0.0 0.095 12.4 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KEY66398.1 - 7e-06 26.3 0.0 0.083 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KEY66398.1 - 1.4e-05 24.9 0.0 0.11 12.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KEY66398.1 - 2.7e-05 23.7 0.9 0.39 10.0 0.0 4.1 4 0 0 4 4 4 1 AAA-like domain AAA_30 PF13604.1 KEY66398.1 - 5.9e-05 22.7 0.5 1.1 8.8 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA PF00004.24 KEY66398.1 - 0.00013 22.1 0.7 6.8 6.9 0.0 4.7 5 0 0 5 5 4 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 KEY66398.1 - 0.00031 20.6 1.0 1.2 9.1 0.1 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 KEY66398.1 - 0.00047 20.1 0.3 0.65 9.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.17 KEY66398.1 - 0.0011 18.4 0.8 0.92 8.9 0.0 2.8 3 0 0 3 3 2 2 SRP54-type protein, GTPase domain AAA_15 PF13175.1 KEY66398.1 - 0.002 17.2 0.0 0.47 9.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 KEY66398.1 - 0.0033 17.1 0.0 4.7 6.9 0.0 3.3 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.12 KEY66398.1 - 0.0033 16.9 0.1 2.3 7.7 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein NB-ARC PF00931.17 KEY66398.1 - 0.0044 15.9 0.1 2.4 6.9 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain AAA_14 PF13173.1 KEY66398.1 - 0.0056 16.5 0.0 5.3 6.9 0.0 3.8 4 0 0 4 4 3 0 AAA domain NACHT PF05729.7 KEY66398.1 - 0.0064 16.1 0.0 1.6 8.3 0.0 3.0 3 0 0 3 3 3 1 NACHT domain DUF3987 PF13148.1 KEY66398.1 - 0.012 14.2 0.0 3.6 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Rad17 PF03215.10 KEY66398.1 - 0.014 14.1 0.0 1.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 KEY66398.1 - 0.021 14.7 0.2 11 5.9 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase KaiC PF06745.8 KEY66398.1 - 0.023 13.8 0.9 0.52 9.3 0.0 2.8 3 0 0 3 3 3 0 KaiC APS_kinase PF01583.15 KEY66398.1 - 0.024 14.3 0.1 7.1 6.2 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase DEAD PF00270.24 KEY66398.1 - 0.027 13.9 0.0 7.7 5.9 0.0 3.3 2 2 0 2 2 2 0 DEAD/DEAH box helicase Zeta_toxin PF06414.7 KEY66398.1 - 0.036 13.1 0.5 6.6 5.7 0.0 3.5 4 0 0 4 4 3 0 Zeta toxin IstB_IS21 PF01695.12 KEY66398.1 - 0.043 13.2 2.9 13 5.1 0.0 4.2 5 0 0 5 5 5 0 IstB-like ATP binding protein DUF87 PF01935.12 KEY66398.1 - 0.054 13.2 0.1 0.96 9.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 KEY66398.1 - 0.059 13.5 0.0 19 5.4 0.0 3.0 2 0 0 2 2 2 0 RNA helicase Synapsin_N PF10581.4 KEY66398.1 - 0.073 12.8 0.0 5.1 7.0 0.0 2.7 2 0 0 2 2 2 0 Synapsin N-terminal PRK PF00485.13 KEY66398.1 - 0.082 12.4 0.1 12 5.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.10 KEY66398.1 - 0.088 12.5 1.8 48 3.6 0.0 4.0 4 0 0 4 4 4 0 NTPase DUF1469 PF07332.6 KEY66398.1 - 7.4 6.3 17.0 5.3 6.7 0.8 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) DJ-1_PfpI PF01965.19 KEY66399.1 - 1.8e-21 76.1 0.0 3e-21 75.4 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.9 KEY66399.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.4 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Molydop_binding PF01568.16 KEY66400.1 - 0.0015 18.2 0.2 0.0033 17.2 0.1 1.6 1 1 0 1 1 1 1 Molydopterin dinucleotide binding domain DUF2945 PF11160.3 KEY66400.1 - 0.048 13.4 0.2 0.09 12.6 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2945) Glyco_hydro_61 PF03443.9 KEY66401.1 - 4.8e-46 157.3 0.0 5.6e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Acetyltransf_7 PF13508.1 KEY66402.1 - 2.4e-05 24.3 0.0 8e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEY66402.1 - 0.00021 21.2 0.0 0.00036 20.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KEY66402.1 - 0.016 15.3 0.0 0.038 14.1 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEY66402.1 - 0.064 13.0 0.2 0.17 11.6 0.1 1.6 1 1 0 1 1 1 0 FR47-like protein adh_short PF00106.20 KEY66404.1 - 1.9e-22 79.9 0.6 2.5e-22 79.5 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY66404.1 - 2.3e-08 34.0 0.0 8.9e-08 32.1 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY66404.1 - 1.4e-05 24.8 0.1 1.8e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KEY66404.1 - 0.093 11.6 0.1 0.16 10.8 0.0 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein FAD_binding_4 PF01565.18 KEY66405.1 - 3.1e-18 65.5 0.4 5.9e-18 64.6 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY66405.1 - 3.7e-10 39.5 0.5 8.6e-10 38.3 0.3 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KEY66405.1 - 0.21 10.7 0.0 0.32 10.1 0.0 1.1 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding GMC_oxred_N PF00732.14 KEY66407.1 - 5e-60 203.1 0.1 7.1e-60 202.6 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY66407.1 - 2.8e-31 108.7 0.0 4.4e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KEY66407.1 - 2.2e-07 30.0 1.0 0.01 14.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KEY66407.1 - 4e-06 25.9 0.4 0.0068 15.3 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEY66407.1 - 2.2e-05 23.5 0.6 3.6e-05 22.8 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KEY66407.1 - 0.014 15.4 0.3 0.15 12.1 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KEY66407.1 - 0.017 13.7 0.1 0.032 12.8 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 KEY66407.1 - 0.029 14.2 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEY66407.1 - 0.044 12.8 0.1 0.081 12.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KEY66407.1 - 0.079 11.4 0.7 0.21 10.0 0.3 1.7 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.11 KEY66407.1 - 0.11 11.9 0.1 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 KEY66407.1 - 0.22 11.3 2.5 6.6 6.5 0.2 2.4 2 0 0 2 2 2 0 ThiF family GMC_oxred_N PF00732.14 KEY66408.1 - 1e-55 189.0 0.0 1.3e-55 188.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY66408.1 - 1.5e-34 119.3 0.1 2.5e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KEY66408.1 - 1.6e-06 27.3 0.2 0.00041 19.3 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEY66408.1 - 3.4e-06 26.1 0.0 1.8e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KEY66408.1 - 0.00019 21.3 0.3 0.00058 19.8 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEY66408.1 - 0.00026 21.1 0.0 0.043 13.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY66408.1 - 0.00052 19.0 0.0 0.00096 18.1 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEY66408.1 - 0.0059 16.5 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEY66408.1 - 0.0099 14.9 0.2 0.019 14.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KEY66408.1 - 0.045 13.5 0.3 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 KEY66408.1 - 0.049 12.0 0.0 0.082 11.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein K_oxygenase PF13434.1 KEY66408.1 - 0.12 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 KEY66408.1 - 0.18 10.4 0.1 0.24 9.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase ADH_zinc_N PF00107.21 KEY66409.1 - 2.7e-08 33.4 0.0 7.1e-08 32.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY66409.1 - 3.2e-05 23.6 0.0 8.5e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ketoacyl-synt PF00109.21 KEY66410.1 - 5.1e-71 239.1 0.0 4.4e-70 236.0 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KEY66410.1 - 3.4e-50 170.2 0.3 1.2e-48 165.2 0.0 2.9 3 0 0 3 3 2 1 KR domain Acyl_transf_1 PF00698.16 KEY66410.1 - 9.3e-50 169.7 0.0 1.8e-49 168.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KEY66410.1 - 4.6e-44 150.2 0.0 5.5e-41 140.2 0.0 3.6 3 0 0 3 3 3 1 short chain dehydrogenase PS-DH PF14765.1 KEY66410.1 - 4.5e-42 144.2 0.0 8.1e-42 143.3 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.7 KEY66410.1 - 6.3e-37 126.8 0.1 2.2e-36 125.0 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 KEY66410.1 - 4.6e-28 97.4 0.0 1.2e-27 96.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KEY66410.1 - 8.9e-17 61.3 0.0 2.1e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 KEY66410.1 - 9.8e-15 54.6 0.0 6.9e-13 48.5 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEY66410.1 - 2.6e-11 42.7 0.0 3.6e-09 35.7 0.0 2.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_18 PF12847.2 KEY66410.1 - 1.4e-09 38.4 0.0 6e-09 36.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY66410.1 - 2.3e-09 37.1 0.0 9.7e-09 35.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY66410.1 - 3.2e-09 37.1 0.0 2.2e-08 34.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY66410.1 - 3.1e-08 33.3 0.0 7.7e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KEY66410.1 - 4.5e-06 26.8 0.0 1.4e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.1 KEY66410.1 - 1.2e-05 25.6 0.0 5.1e-05 23.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY66410.1 - 0.0015 17.7 0.0 0.0035 16.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 KEY66410.1 - 0.0021 17.0 0.0 0.0045 15.9 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain NAD_binding_10 PF13460.1 KEY66410.1 - 0.0025 17.8 0.1 0.0098 15.9 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KEY66410.1 - 0.0031 16.4 0.0 0.015 14.1 0.0 2.1 2 1 0 2 2 2 1 RmlD substrate binding domain Methyltransf_26 PF13659.1 KEY66410.1 - 0.0054 16.7 0.0 0.041 13.9 0.0 2.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KEY66410.1 - 0.0085 15.5 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Semialdhyde_dh PF01118.19 KEY66410.1 - 0.0091 16.2 0.0 0.053 13.8 0.0 2.4 2 0 0 2 2 1 1 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_PK PF05891.7 KEY66410.1 - 0.018 14.3 0.0 0.083 12.1 0.0 1.9 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase RrnaAD PF00398.15 KEY66410.1 - 0.046 12.7 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DREV PF05219.7 KEY66410.1 - 0.079 11.8 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Lipoxygenase PF00305.14 KEY66410.1 - 1.7 6.5 0.0 2.9 5.7 0.0 1.2 1 0 0 1 1 1 0 Lipoxygenase Alpha_L_fucos PF01120.12 KEY66411.1 - 6.3e-92 308.1 1.6 7.9e-92 307.8 1.1 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Mif2_N PF15624.1 KEY66412.1 - 9.3e-34 116.9 1.6 9.3e-34 116.9 1.1 3.1 1 1 2 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal RNase_HII PF01351.13 KEY66413.1 - 6.6e-45 153.1 0.0 9.1e-45 152.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII RHD3 PF05879.7 KEY66414.1 - 0 1054.2 0.0 0 1053.9 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 KEY66414.1 - 3.3e-08 32.8 0.1 5.5e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 KEY66414.1 - 7e-07 29.2 0.0 1.5e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 KEY66414.1 - 3.2e-05 24.4 0.0 7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KEY66414.1 - 8.8e-05 22.4 0.0 0.00026 20.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 KEY66414.1 - 0.00075 19.4 0.0 0.0027 17.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 KEY66414.1 - 0.034 13.1 0.1 0.06 12.3 0.1 1.3 1 0 0 1 1 1 0 Septin DLH PF01738.13 KEY66415.1 - 5.5e-24 84.6 0.0 7.6e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KEY66415.1 - 0.00069 19.3 0.0 0.00098 18.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KEY66415.1 - 0.029 13.8 0.0 0.053 12.9 0.0 1.4 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 KEY66415.1 - 0.029 14.0 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal MS_channel PF00924.13 KEY66416.1 - 1.5e-16 60.3 1.0 2.6e-16 59.5 0.7 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_6 PF13405.1 KEY66416.1 - 0.014 15.2 0.0 0.084 12.7 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.27 KEY66416.1 - 0.022 14.0 0.1 0.052 12.8 0.1 1.6 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.1 KEY66416.1 - 0.12 11.7 0.1 0.12 11.7 0.1 1.7 2 0 0 2 2 2 0 EF hand Sugar_tr PF00083.19 KEY66417.1 - 6.1e-85 285.4 23.4 7.7e-85 285.1 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY66417.1 - 6.9e-14 51.3 48.1 6e-09 35.0 11.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Abp2 PF09441.5 KEY66418.1 - 4e-71 238.5 0.0 5.9e-71 238.0 0.0 1.2 1 0 0 1 1 1 1 ARS binding protein 2 DUF3128 PF11326.3 KEY66418.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) Sds3 PF08598.6 KEY66420.1 - 6.2e-49 166.3 2.3 8.2e-49 165.9 1.6 1.2 1 0 0 1 1 1 1 Sds3-like OmpH PF03938.9 KEY66420.1 - 0.72 9.7 6.5 4.9 7.0 0.2 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) COG5 PF10392.4 KEY66421.1 - 0.031 14.2 6.6 0.043 13.7 1.3 3.3 3 1 0 3 3 3 0 Golgi transport complex subunit 5 Spore_II_R PF09551.5 KEY66421.1 - 0.18 11.8 2.0 0.45 10.5 1.4 1.6 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) Iron_permease PF04120.7 KEY66421.1 - 0.35 10.4 2.4 0.78 9.3 1.6 1.5 1 0 0 1 1 1 0 Low affinity iron permease CHASE3 PF05227.8 KEY66421.1 - 0.56 9.8 8.6 0.36 10.5 3.4 2.5 2 1 1 3 3 3 0 CHASE3 domain DUF883 PF05957.8 KEY66421.1 - 1.1 9.6 10.8 0.57 10.6 0.3 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Laminin_II PF06009.7 KEY66421.1 - 2.1 8.1 8.7 1.4 8.6 2.4 2.3 2 0 0 2 2 2 0 Laminin Domain II Apolipoprotein PF01442.13 KEY66421.1 - 2.6 7.4 12.1 1.1 8.7 0.8 3.0 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain Ala_racemase_N PF01168.15 KEY66422.1 - 1.8e-38 132.3 0.0 2.1e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.15 KEY66423.1 - 1.1e-121 406.7 9.2 1.3e-121 406.5 6.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 KEY66423.1 - 2.2e-45 153.2 0.0 6.1e-45 151.8 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 KEY66423.1 - 1e-16 61.2 0.0 2e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Methyltransf_12 PF08242.7 KEY66424.1 - 2.1e-10 40.9 0.0 3.8e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY66424.1 - 4.7e-10 39.8 0.0 1.3e-09 38.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY66424.1 - 2.8e-08 33.6 0.0 5.1e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY66424.1 - 7.6e-06 25.5 0.0 1.9e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY66424.1 - 0.0066 15.5 0.0 0.019 14.1 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family P16-Arc PF04699.9 KEY66425.1 - 5.8e-36 123.7 0.0 7.9e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) AFT PF08731.6 KEY66427.1 - 0.0044 17.1 0.0 0.0078 16.3 0.0 1.4 1 0 0 1 1 1 1 Transcription factor AFT Kunitz_legume PF00197.13 KEY66427.1 - 0.033 13.7 0.0 0.076 12.5 0.0 1.6 2 0 0 2 2 2 0 Trypsin and protease inhibitor DBD_Tnp_Mut PF03108.10 KEY66427.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 MuDR family transposase CN_hydrolase PF00795.17 KEY66429.1 - 3.5e-19 68.8 0.0 9e-19 67.5 0.0 1.7 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TAF4 PF05236.9 KEY66429.1 - 1.1e-10 41.2 0.3 4.8e-09 35.8 0.0 2.8 3 0 0 3 3 3 1 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.3 KEY66430.1 - 8.9e-75 250.7 0.0 3.4e-72 242.2 0.0 2.1 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 KEY66430.1 - 1.1e-32 112.5 0.0 4.5e-31 107.4 0.0 2.3 1 1 1 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 KEY66430.1 - 4e-14 52.7 0.4 7.9e-14 51.7 0.3 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KEY66430.1 - 9.4e-12 44.8 0.7 1.6e-11 44.1 0.5 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 KEY66430.1 - 1.8e-07 30.8 0.6 3.7e-07 29.8 0.4 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 KEY66430.1 - 3.1e-05 23.7 0.2 7.2e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain V_ATPase_I PF01496.14 KEY66431.1 - 1.1e-302 1005.5 0.4 1.3e-302 1005.3 0.3 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ERM PF00769.14 KEY66431.1 - 0.0041 16.7 2.3 0.04 13.4 0.0 2.2 2 0 0 2 2 2 1 Ezrin/radixin/moesin family Filament PF00038.16 KEY66431.1 - 0.0089 15.5 8.4 0.074 12.5 1.1 2.3 2 0 0 2 2 2 2 Intermediate filament protein IncA PF04156.9 KEY66431.1 - 0.048 13.2 3.8 0.21 11.1 0.4 2.5 2 0 0 2 2 2 0 IncA protein AAA_13 PF13166.1 KEY66431.1 - 0.057 11.8 2.9 0.6 8.4 0.8 2.0 2 0 0 2 2 2 0 AAA domain Mod_r PF07200.8 KEY66431.1 - 0.066 13.1 5.2 0.41 10.5 0.2 2.4 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF3552 PF12072.3 KEY66431.1 - 0.22 10.7 3.1 8.8 5.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Baculo_PEP_C PF04513.7 KEY66431.1 - 0.36 10.6 6.3 0.5 10.1 1.0 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4140 PF13600.1 KEY66431.1 - 0.59 10.6 4.0 16 6.0 0.3 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TBPIP PF07106.8 KEY66431.1 - 0.66 9.5 6.4 0.65 9.5 0.1 2.5 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 KEY66431.1 - 1.4 8.4 8.2 0.37 10.2 0.5 3.3 3 0 0 3 3 3 0 Septum formation initiator Laminin_II PF06009.7 KEY66431.1 - 2 8.1 5.9 16 5.2 1.9 2.4 2 0 0 2 2 2 0 Laminin Domain II Syntaxin PF00804.20 KEY66431.1 - 7.1 6.8 7.3 0.98 9.6 0.9 2.4 3 0 0 3 3 2 0 Syntaxin LRR_6 PF13516.1 KEY66432.1 - 0.0055 16.6 0.0 3.5 7.9 0.0 4.1 4 0 0 4 4 4 1 Leucine Rich repeat LRR_8 PF13855.1 KEY66432.1 - 0.015 15.0 4.1 2.5 7.9 0.0 4.2 5 0 0 5 5 5 0 Leucine rich repeat F-box-like PF12937.2 KEY66432.1 - 0.042 13.5 0.4 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 F-box-like PHD PF00628.24 KEY66433.1 - 5.7e-10 38.7 7.3 9.1e-10 38.0 5.1 1.3 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 KEY66433.1 - 6e-05 23.2 0.7 6e-05 23.2 0.5 2.9 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Prenyltransf PF01255.14 KEY66434.1 - 1.2e-85 286.2 0.0 2e-85 285.4 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase AP_endonuc_2 PF01261.19 KEY66434.1 - 0.097 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Glyco_hydro_63 PF03200.11 KEY66435.1 - 9.8e-10 36.9 3.5 4.6e-07 28.1 0.1 3.6 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase OSCP PF00213.13 KEY66436.1 - 6.8e-46 156.2 0.6 8.1e-46 156.0 0.4 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit HTH_IclR PF09339.5 KEY66436.1 - 0.014 15.0 0.0 0.034 13.7 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain Mob1_phocein PF03637.12 KEY66437.1 - 1.3e-69 233.3 0.0 1.7e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family DBR1 PF05011.8 KEY66438.1 - 4.8e-48 162.7 0.0 8.7e-48 161.8 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KEY66438.1 - 3.8e-10 39.4 1.5 8.1e-10 38.4 1.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Skp1_POZ PF03931.10 KEY66439.1 - 1.4e-08 34.7 0.0 1.9e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Ras PF00071.17 KEY66440.1 - 1.7e-47 160.8 0.0 2.4e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEY66440.1 - 1.5e-11 44.8 0.0 2.7e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEY66440.1 - 1.8e-05 24.0 0.0 5.6e-05 22.4 0.0 1.9 1 1 1 2 2 2 1 ADP-ribosylation factor family DASH_Dad1 PF08649.5 KEY66441.1 - 7.4e-21 73.6 3.2 1.2e-13 50.4 0.2 2.1 2 0 0 2 2 2 2 DASH complex subunit Dad1 FAM117 PF15388.1 KEY66441.1 - 0.031 13.5 0.2 0.032 13.4 0.2 1.1 1 0 0 1 1 1 0 Protein Family FAM117 Glutaredoxin2_C PF04399.8 KEY66441.1 - 0.046 13.3 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Peptidase_M7 PF02031.11 KEY66441.1 - 0.046 13.4 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family DS PF01916.12 KEY66443.1 - 1.2e-143 477.7 0.0 1.4e-143 477.5 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 KEY66443.1 - 0.028 13.5 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Carbamoyltransferase Aldo_ket_red PF00248.16 KEY66444.1 - 2.5e-22 79.0 0.0 3e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family GFO_IDH_MocA PF01408.17 KEY66445.1 - 9.5e-19 68.0 0.1 1.9e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 KEY66445.1 - 0.0037 17.6 0.1 0.0075 16.6 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 KEY66446.1 - 1.2e-11 44.9 0.0 2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY66446.1 - 2.5e-07 30.5 0.0 3.8e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY66446.1 - 3.2e-06 27.5 0.0 6.4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY66446.1 - 8.4e-06 26.0 0.0 1.5e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY66446.1 - 3.1e-05 24.5 0.1 6.8e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY66446.1 - 0.00016 21.2 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY66446.1 - 0.00025 21.0 0.3 0.00048 20.1 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Myb_DNA-binding PF00249.26 KEY66447.1 - 3.3e-10 39.8 1.2 5.2e-09 36.0 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEY66447.1 - 1.1e-07 31.8 0.5 3.9e-05 23.6 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain CAP_GLY PF01302.20 KEY66448.1 - 5e-24 83.7 1.4 7.6e-24 83.2 1.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 KEY66448.1 - 1.2e-20 73.5 0.0 1.9e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 KEY66448.1 - 0.00025 20.3 0.0 0.0005 19.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family zf-RING_2 PF13639.1 KEY66449.1 - 3.6e-14 52.3 5.0 6.9e-14 51.3 3.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEY66449.1 - 5.9e-08 32.7 0.9 1.2e-07 31.7 0.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KEY66449.1 - 7.3e-07 28.7 3.5 1.3e-06 27.9 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY66449.1 - 1.1e-06 28.2 2.4 2.4e-06 27.1 1.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEY66449.1 - 2.8e-06 27.2 5.4 5.1e-06 26.4 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEY66449.1 - 2.2e-05 24.0 2.8 4.4e-05 23.0 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEY66449.1 - 0.0011 18.7 0.8 0.0023 17.7 0.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KEY66449.1 - 0.034 13.7 2.7 0.063 12.8 1.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Glyco_hydro_cc PF11790.3 KEY66450.1 - 1e-57 195.3 0.1 1.5e-57 194.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Zn_clus PF00172.13 KEY66451.1 - 2.7e-08 33.5 9.3 4.5e-08 32.8 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEY66451.1 - 8.7e-06 24.5 0.1 1.3e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CLAMP PF14769.1 KEY66451.1 - 0.26 11.4 1.8 2.1 8.5 0.3 2.5 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 LtrA PF06772.6 KEY66453.1 - 7.2e-18 64.6 15.8 4.1e-15 55.5 11.0 2.3 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) IncA PF04156.9 KEY66453.1 - 0.25 10.9 0.4 0.88 9.1 0.1 2.0 2 0 0 2 2 2 0 IncA protein ATP-synt_Eps PF04627.8 KEY66454.1 - 6.6e-25 86.4 3.9 1.1e-24 85.7 2.7 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Mak10 PF04112.8 KEY66455.1 - 1.7e-49 167.2 0.0 3.3e-49 166.3 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Mito_carr PF00153.22 KEY66456.1 - 5.5e-54 179.8 2.8 1.9e-17 62.7 0.2 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein TIM21 PF08294.6 KEY66457.1 - 0.55 9.8 0.1 5.5 6.6 0.0 2.2 2 0 0 2 2 2 0 TIM21 PCI PF01399.22 KEY66458.1 - 1.6e-19 70.1 0.8 6.3e-19 68.2 0.1 2.3 3 1 0 3 3 3 1 PCI domain TPR_7 PF13176.1 KEY66458.1 - 4.4e-05 22.9 4.0 0.2 11.5 0.2 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEY66458.1 - 0.00018 21.0 3.7 4 7.4 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat DDRGK PF09756.4 KEY66458.1 - 0.00071 19.0 0.2 0.00071 19.0 0.1 1.7 2 0 0 2 2 2 1 DDRGK domain TPR_1 PF00515.23 KEY66458.1 - 0.025 14.1 0.3 27 4.5 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF87 PF01935.12 KEY66458.1 - 0.033 14.0 2.3 0.2 11.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 TPR_2 PF07719.12 KEY66458.1 - 0.067 13.1 6.0 7.3 6.7 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 KEY66458.1 - 0.072 12.8 0.4 0.18 11.5 0.3 1.6 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Med2 PF11214.3 KEY66458.1 - 0.083 12.9 0.5 0.38 10.8 0.0 2.4 2 1 0 2 2 2 0 Mediator complex subunit 2 TPR_4 PF07721.9 KEY66458.1 - 0.095 13.1 1.9 0.51 10.9 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEY66458.1 - 0.23 11.4 13.6 0.27 11.2 0.3 4.7 3 2 3 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEY66458.1 - 0.25 12.0 11.6 17 6.3 0.1 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEY66458.1 - 2.8 8.0 5.9 14 5.7 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_18 PF00704.23 KEY66459.1 - 1.3e-67 228.6 0.0 1.6e-67 228.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 zf-CCCH PF00642.19 KEY66460.1 - 4.4e-20 70.8 33.6 1.7e-07 30.7 0.4 5.5 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Methyltransf_23 PF13489.1 KEY66460.1 - 1.1e-10 41.4 0.0 1.9e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY66460.1 - 0.00023 21.6 0.0 0.00088 19.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY66460.1 - 0.023 15.2 0.0 0.15 12.6 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KEY66460.1 - 0.028 14.8 0.0 0.056 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF1776 PF08643.5 KEY66461.1 - 2.4e-105 351.9 0.0 3e-105 351.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) HET PF06985.6 KEY66462.1 - 2.2e-22 79.6 0.0 4.9e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sulf_transp PF04143.9 KEY66463.1 - 7.4e-14 51.5 30.8 2.3e-09 37.1 7.4 4.4 5 2 0 5 5 5 2 Sulphur transport Pkinase PF00069.20 KEY66464.1 - 4.3e-09 35.9 0.0 1.1e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEY66464.1 - 0.16 11.0 0.0 1 8.3 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase HMGL-like PF00682.14 KEY66467.1 - 3.3e-64 216.7 0.0 4.5e-64 216.3 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 KEY66467.1 - 1.5e-25 89.5 0.0 5.1e-25 87.7 0.0 1.9 2 1 0 2 2 2 1 LeuA allosteric (dimerisation) domain DUF1726 PF08351.6 KEY66467.1 - 0.058 13.0 0.0 0.47 10.1 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1726) Myb_DNA-bind_6 PF13921.1 KEY66468.1 - 0.13 12.4 0.3 0.13 12.4 0.2 3.7 3 1 1 4 4 4 0 Myb-like DNA-binding domain Aminotran_5 PF00266.14 KEY66469.1 - 6.3e-29 100.8 0.0 8.3e-19 67.5 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Bac_luciferase PF00296.15 KEY66470.1 - 4.2e-58 196.8 1.3 6.9e-58 196.1 0.9 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF3435 PF11917.3 KEY66470.1 - 3.1e-14 52.5 0.2 1.3e-09 37.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3435) p450 PF00067.17 KEY66471.1 - 1.3e-47 162.4 0.0 1.6e-47 162.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Oxidored_FMN PF00724.15 KEY66472.1 - 9.3e-64 215.5 0.0 1.3e-63 215.1 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans PF04082.13 KEY66472.1 - 2.1e-24 85.8 0.5 3.4e-24 85.1 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY66472.1 - 1.5e-05 24.7 16.5 1.5e-05 24.7 11.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 KEY66473.1 - 1.9e-12 46.8 0.0 3.7e-11 42.7 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY66473.1 - 6e-07 29.0 2.3 1.2e-06 28.0 1.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Abhydrolase_6 PF12697.2 KEY66474.1 - 6.8e-22 78.4 0.0 8e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY66474.1 - 2.9e-08 33.5 0.0 4.1e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY66474.1 - 3.8e-08 33.2 0.0 5.1e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KEY66474.1 - 1.6e-06 27.8 0.0 9.6e-06 25.3 0.0 2.1 1 1 1 2 2 2 1 Putative lysophospholipase Bac_luciferase PF00296.15 KEY66475.1 - 1.3e-57 195.2 1.0 1.8e-57 194.8 0.7 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Aa_trans PF01490.13 KEY66476.1 - 6.4e-21 74.3 33.3 2.7e-20 72.2 23.1 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Glyco_hydro_43 PF04616.9 KEY66478.1 - 0.0012 18.0 0.9 0.013 14.5 0.4 2.5 1 1 1 2 2 2 1 Glycosyl hydrolases family 43 EGF_2 PF07974.8 KEY66478.1 - 0.0012 19.0 6.7 0.0085 16.2 4.6 2.2 1 1 0 1 1 1 1 EGF-like domain hEGF PF12661.2 KEY66478.1 - 0.0038 17.2 2.9 0.0038 17.2 2.0 2.4 2 0 0 2 2 2 1 Human growth factor-like EGF Squash PF00299.13 KEY66478.1 - 1.3 8.9 6.6 0.45 10.3 1.9 2.1 2 0 0 2 2 2 0 Squash family serine protease inhibitor Aminotran_1_2 PF00155.16 KEY66479.1 - 2.1e-37 128.9 0.0 3.1e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_S9 PF00326.16 KEY66479.1 - 1.8e-15 56.7 0.0 3.2e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KEY66479.1 - 1.6e-06 27.8 0.6 7.1e-06 25.7 0.1 2.4 2 2 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY66479.1 - 5.3e-06 26.2 0.6 3.3e-05 23.6 0.1 2.4 3 0 0 3 3 3 1 Alpha/beta hydrolase family DLH PF01738.13 KEY66479.1 - 1e-05 24.9 0.0 4e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF2048 PF09752.4 KEY66479.1 - 0.034 13.0 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) LIP PF03583.9 KEY66479.1 - 0.41 9.8 2.8 4.8 6.2 0.0 2.7 3 0 0 3 3 3 0 Secretory lipase HET PF06985.6 KEY66480.1 - 4.7e-33 114.2 0.9 9.4e-33 113.3 0.6 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HATPase_c PF02518.21 KEY66481.1 - 1.8e-29 101.6 0.1 3.6e-29 100.7 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KEY66481.1 - 2.1e-22 78.8 0.0 6.3e-22 77.3 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 KEY66481.1 - 2.1e-22 79.2 0.1 4.2e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 KEY66481.1 - 9.6e-16 58.0 0.1 1.8e-08 34.7 0.0 4.2 5 0 0 5 5 5 2 PAS domain PAS_3 PF08447.6 KEY66481.1 - 2e-15 56.6 0.1 4.8e-15 55.4 0.1 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 KEY66481.1 - 2.1e-08 34.1 0.7 0.0026 17.7 0.0 5.0 4 2 0 4 4 4 2 PAS fold PAS_8 PF13188.1 KEY66481.1 - 0.00036 20.2 0.0 0.19 11.6 0.0 4.1 4 0 0 4 4 4 1 PAS domain PAS PF00989.19 KEY66481.1 - 0.00037 20.2 0.0 1.3 8.8 0.0 4.2 4 0 0 4 4 4 1 PAS fold HATPase_c_3 PF13589.1 KEY66481.1 - 0.026 14.1 0.0 0.067 12.8 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ApbA PF02558.11 KEY66483.1 - 0.047 13.1 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA WLM PF08325.5 KEY66484.1 - 4.5e-55 186.4 0.0 7.8e-55 185.6 0.0 1.4 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 KEY66484.1 - 0.0016 17.5 19.3 0.01 14.8 1.8 3.3 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.2 KEY66484.1 - 0.13 12.0 15.5 0.53 10.1 10.7 1.9 1 1 0 1 1 1 0 Double zinc ribbon Peptidase_M54 PF07998.6 KEY66484.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 DUF45 PF01863.12 KEY66484.1 - 0.35 10.6 5.6 0.062 13.0 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF45 zf-Sec23_Sec24 PF04810.10 KEY66484.1 - 8.7 5.9 13.6 6.2 6.4 0.6 3.4 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger Methyltransf_31 PF13847.1 KEY66485.1 - 8.4e-15 54.6 0.0 1.2e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY66485.1 - 1.3e-11 44.8 0.0 2.5e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY66485.1 - 2.2e-11 44.0 0.2 7.1e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY66485.1 - 6e-11 42.9 0.1 1.1e-10 42.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY66485.1 - 2.5e-09 37.0 0.0 3.8e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY66485.1 - 5.4e-08 32.3 0.1 8.5e-08 31.7 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KEY66485.1 - 6.5e-07 29.6 0.1 1.4e-06 28.5 0.1 1.6 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.14 KEY66485.1 - 7e-07 28.9 0.0 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 KEY66485.1 - 1.6e-06 28.1 0.3 3.9e-06 26.8 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KEY66485.1 - 0.00012 21.1 0.0 0.00017 20.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 KEY66485.1 - 0.001 18.8 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KEY66485.1 - 0.0042 16.6 0.0 0.006 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.8 KEY66485.1 - 0.0054 15.8 0.1 0.0076 15.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KEY66485.1 - 0.0065 15.6 0.0 0.013 14.6 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KEY66485.1 - 0.029 13.4 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 KEY66485.1 - 0.059 12.0 0.0 0.067 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Amidase PF01425.16 KEY66486.1 - 5e-87 292.5 0.0 5.9e-87 292.3 0.0 1.0 1 0 0 1 1 1 1 Amidase FAD_binding_8 PF08022.7 KEY66488.1 - 2.3e-22 78.8 0.0 4.6e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KEY66488.1 - 3.5e-22 78.9 0.0 5.7e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KEY66488.1 - 2.1e-18 66.6 9.0 2.1e-18 66.6 6.3 2.1 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KEY66488.1 - 6.3e-05 23.0 0.0 0.00018 21.5 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain DUF2975 PF11188.3 KEY66488.1 - 0.11 12.1 0.6 0.54 9.9 0.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) NAD_binding_1 PF00175.16 KEY66488.1 - 0.16 12.5 0.0 8.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain LrgA PF03788.9 KEY66488.1 - 0.18 11.5 1.2 0.25 11.0 0.1 1.7 2 0 0 2 2 2 0 LrgA family C2 PF00168.25 KEY66489.1 - 3.9e-18 65.0 0.0 1.1e-10 41.2 0.0 2.6 2 0 0 2 2 2 2 C2 domain Saccharop_dh PF03435.13 KEY66490.1 - 2.3e-17 63.0 0.1 3.1e-17 62.6 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KEY66490.1 - 0.035 14.2 0.0 0.077 13.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 KEY66490.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF1713 PF08213.6 KEY66492.1 - 8.7e-12 44.4 21.6 8.7e-12 44.4 14.9 1.8 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 KEY66492.1 - 0.0015 18.4 0.3 0.0028 17.6 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial protein Pet20 Snapin_Pallidin PF14712.1 KEY66492.1 - 6.7 7.1 7.9 4.6 7.6 0.1 2.4 2 0 0 2 2 2 0 Snapin/Pallidin GNAT_acetyltr_2 PF13718.1 KEY66493.1 - 5e-81 270.7 0.0 8.8e-81 269.9 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 KEY66493.1 - 4.1e-65 218.6 0.0 2.4e-64 216.2 0.0 2.2 2 1 0 2 2 2 1 Helicase DUF1726 PF08351.6 KEY66493.1 - 2e-39 133.1 0.0 6.5e-39 131.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 KEY66493.1 - 4e-34 116.7 0.5 1.5e-33 114.9 0.3 2.0 1 0 0 1 1 1 1 Possible tRNA binding domain AAA_22 PF13401.1 KEY66493.1 - 0.0015 18.7 0.0 0.14 12.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain Acetyltransf_7 PF13508.1 KEY66493.1 - 0.0021 18.1 0.0 0.0077 16.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF2376 PF09550.5 KEY66493.1 - 0.045 13.9 0.1 0.19 11.8 0.1 2.2 1 0 0 1 1 1 0 Conserved hypothetical phage protein (DUF2376) Acetyltransf_1 PF00583.19 KEY66493.1 - 0.11 12.5 0.0 0.35 10.9 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MR_MLE_C PF13378.1 KEY66494.1 - 2.1e-32 111.3 0.1 6.7e-32 109.7 0.0 1.8 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 KEY66494.1 - 1.1e-14 54.3 0.0 2.3e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 KEY66494.1 - 1.4e-09 38.3 0.0 4e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAAL_C PF07476.6 KEY66494.1 - 0.15 10.9 0.0 0.34 9.7 0.0 1.5 1 1 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus ADH_N PF08240.7 KEY66495.1 - 6.1e-28 96.7 0.5 1.2e-27 95.7 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY66495.1 - 9.6e-12 44.5 0.2 2e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 KEY66495.1 - 0.00051 20.1 0.6 0.0047 17.0 0.2 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 KEY66495.1 - 0.015 15.3 0.1 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KEY66495.1 - 0.021 14.6 0.3 0.046 13.5 0.2 1.5 1 0 0 1 1 1 0 ThiF family ApbA PF02558.11 KEY66495.1 - 0.027 13.9 0.9 0.1 12.0 0.5 2.0 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA Cpn10 PF00166.16 KEY66495.1 - 0.12 12.2 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Chaperonin 10 Kd subunit Dak1 PF02733.12 KEY66496.1 - 2.2e-114 381.4 2.9 2.2e-114 381.4 2.0 1.7 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.12 KEY66496.1 - 1.6e-40 138.6 0.3 3.1e-40 137.6 0.2 1.5 1 0 0 1 1 1 1 DAK2 domain DUF3716 PF12511.3 KEY66497.1 - 8.1e-10 38.1 2.3 1.4e-09 37.4 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Nucleoplasmin PF03066.10 KEY66498.1 - 0.058 12.9 5.7 0.066 12.7 0.2 2.1 2 0 0 2 2 2 0 Nucleoplasmin Ribosomal_60s PF00428.14 KEY66498.1 - 0.062 13.6 1.5 0.062 13.6 1.0 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4448 PF14610.1 KEY66499.1 - 4.7e-28 97.9 0.0 6.4e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) JmjC PF02373.17 KEY66500.1 - 7.5e-21 74.5 0.0 1.4e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase UDPGT PF00201.13 KEY66501.1 - 7.5e-22 77.5 0.0 2.5e-21 75.8 0.0 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KEY66501.1 - 0.0016 18.1 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KEY66501.1 - 0.0017 17.6 0.0 0.048 12.8 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 1 GIT_SHD PF08518.6 KEY66502.1 - 8.2e-20 69.8 6.0 1.3e-13 50.0 0.9 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF3138 PF11336.3 KEY66502.1 - 1.8 6.6 8.2 3.3 5.7 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Bacillus_HBL PF05791.6 KEY66502.1 - 4.9 6.4 22.4 0.34 10.2 4.2 4.1 2 1 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Reo_sigmaC PF04582.7 KEY66502.1 - 5.1 6.1 8.3 8.4 5.4 0.3 3.1 2 1 1 4 4 4 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 KEY66502.1 - 6.9 4.9 26.1 3.7 5.8 11.2 2.2 1 1 1 2 2 2 0 AAA domain Ssu72 PF04722.8 KEY66503.1 - 3.5e-85 284.2 0.0 4.1e-85 284.0 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein SH3_1 PF00018.23 KEY66504.1 - 2.2e-09 36.5 0.0 4e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KEY66504.1 - 6.4e-09 35.2 0.2 1.5e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KEY66504.1 - 6.2e-05 22.4 0.1 0.0011 18.3 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain NAD_binding_1 PF00175.16 KEY66507.1 - 2.1e-29 102.2 0.0 4e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KEY66507.1 - 4.1e-21 74.9 0.0 8.2e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KEY66507.1 - 3.3e-09 36.8 0.0 0.0002 21.2 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KEY66507.1 - 0.00092 19.1 0.0 0.0027 17.6 0.0 1.8 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain Peptidase_M28 PF04389.12 KEY66508.1 - 1.4e-16 60.7 0.0 2.5e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 KEY66508.1 - 6.8e-13 48.2 0.0 1.2e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 KEY66508.1 - 2.3e-06 27.2 0.1 6.2e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 KEY66508.1 - 0.00071 19.1 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 KEY66508.1 - 0.0072 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Nicastrin MFS_1 PF07690.11 KEY66509.1 - 1.9e-37 128.8 33.8 8.6e-28 97.0 5.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY66509.1 - 2.3e-10 39.6 5.8 2.3e-10 39.6 4.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KEY66509.1 - 1.1e-06 27.3 24.0 0.00021 19.8 0.5 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein SprT-like PF10263.4 KEY66510.1 - 9.1e-14 51.4 0.1 1.8e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 SprT-like family Epimerase PF01370.16 KEY66512.1 - 2.7e-10 40.1 0.0 0.00012 21.6 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KEY66512.1 - 0.0096 16.2 0.1 0.028 14.7 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KEY66512.1 - 0.013 15.5 0.0 0.041 13.9 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 KEY66512.1 - 0.17 10.5 0.0 0.43 9.2 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family TFIIS_M PF07500.9 KEY66514.1 - 1.7e-26 92.5 2.4 3.2e-26 91.6 0.2 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 KEY66514.1 - 1.6e-18 65.9 8.4 2.8e-18 65.2 5.8 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 KEY66514.1 - 1.4e-13 50.0 0.2 4.1e-13 48.5 0.2 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain PALP PF00291.20 KEY66515.1 - 1.7e-53 181.8 0.5 2.2e-53 181.4 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.12 KEY66516.1 - 2e-37 128.9 0.0 2.8e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 KEY66516.1 - 0.0036 16.2 0.0 0.0054 15.6 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase tRNA-synt_2c PF01411.14 KEY66517.1 - 1.7e-211 703.3 0.0 2.2e-211 702.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KEY66517.1 - 2.3e-16 59.3 0.2 2.3e-16 59.3 0.1 2.1 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 KEY66517.1 - 0.0011 18.6 0.6 0.0032 17.1 0.4 1.9 1 0 0 1 1 1 1 DHHA1 domain XPC-binding PF09280.6 KEY66517.1 - 0.39 10.2 5.1 0.054 12.9 0.3 1.9 2 0 0 2 2 2 0 XPC-binding domain MDFI PF15316.1 KEY66518.1 - 0.083 12.8 0.0 0.17 11.8 0.0 1.5 2 0 0 2 2 2 0 MyoD family inhibitor Senescence_reg PF04520.8 KEY66518.1 - 0.11 13.0 2.1 0.28 11.6 0.8 2.3 1 1 1 2 2 2 0 Senescence regulator RCR PF12273.3 KEY66519.1 - 2.4e-08 34.6 1.2 3.7e-08 33.9 0.8 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Sel1 PF08238.7 KEY66520.1 - 1.9e-43 145.8 49.2 0.0001 22.7 0.0 14.0 13 1 1 14 14 14 10 Sel1 repeat TPR_17 PF13431.1 KEY66520.1 - 0.0017 18.4 7.5 20 5.7 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEY66520.1 - 0.0038 16.9 6.2 15 5.6 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEY66520.1 - 0.045 14.2 16.4 4.3 8.0 0.3 7.8 8 0 0 8 8 8 0 Tetratricopeptide repeat HemY_N PF07219.8 KEY66520.1 - 8.3 6.0 7.1 2.6 7.6 0.2 3.3 4 0 0 4 4 4 0 HemY protein N-terminus UDG PF03167.14 KEY66521.1 - 2.1e-24 85.7 0.0 3.3e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF1708 PF08101.6 KEY66522.1 - 6.8e-147 489.6 0.0 9.6e-147 489.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF726 PF05277.7 KEY66523.1 - 5.9e-110 367.3 0.3 7.7e-110 367.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 KEY66523.1 - 0.0005 20.0 0.1 0.0011 18.9 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KEY66523.1 - 0.00082 19.6 0.3 0.0024 18.1 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_5 PF12695.2 KEY66523.1 - 0.00088 19.0 0.0 0.0023 17.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KEY66523.1 - 0.0067 16.1 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.20 KEY66523.1 - 0.01 15.4 0.0 0.041 13.5 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 3) PE-PPE PF08237.6 KEY66523.1 - 0.049 13.0 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain DRIM PF07539.7 KEY66523.1 - 0.12 11.7 0.2 2.3 7.6 0.1 2.4 1 1 0 1 1 1 0 Down-regulated in metastasis Gly-zipper_OmpA PF13436.1 KEY66523.1 - 0.64 9.7 8.8 7.8 6.1 3.4 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Nop53 PF07767.6 KEY66524.1 - 0.25 10.2 31.6 0.36 9.7 21.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CAF-1_p150 PF11600.3 KEY66524.1 - 0.41 10.0 44.6 0.53 9.6 30.9 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Nucleo_P87 PF07267.6 KEY66524.1 - 2.9 6.4 11.3 3.1 6.3 7.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Thg1C PF14413.1 KEY66525.1 - 5.9e-53 177.6 0.1 7.7e-53 177.3 0.1 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 KEY66525.1 - 6e-45 152.1 0.0 8.2e-45 151.7 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase WD40 PF00400.27 KEY66526.1 - 2.5e-09 36.6 3.3 0.026 14.4 0.2 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.6 KEY66526.1 - 5.9e-05 22.8 0.2 0.49 10.0 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 KEY66526.1 - 0.0004 19.9 0.1 0.0013 18.2 0.0 1.8 2 0 0 2 2 2 1 PQQ-like domain RNA_pol_Rpb1_1 PF04997.7 KEY66527.1 - 6.3e-109 364.2 0.0 9.1e-109 363.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 KEY66527.1 - 3.3e-100 334.9 0.0 5.6e-100 334.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KEY66527.1 - 8.9e-70 233.9 0.0 2.2e-69 232.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 KEY66527.1 - 1.2e-52 178.4 0.4 1.9e-52 177.7 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 KEY66527.1 - 1e-43 148.7 0.0 2.3e-43 147.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 KEY66527.1 - 4.4e-43 146.2 0.5 2.1e-42 144.0 0.5 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 KEY66527.1 - 1.9e-36 124.1 0.1 4.3e-36 122.9 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 FAD_binding_4 PF01565.18 KEY66528.1 - 2.3e-23 82.2 1.1 4.2e-23 81.3 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY66528.1 - 1.2e-05 25.0 0.0 2.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like FAD-oxidase_C PF02913.14 KEY66528.1 - 0.00093 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FMN_dh PF01070.13 KEY66529.1 - 2e-109 365.7 0.0 2.4e-109 365.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KEY66529.1 - 3.3e-05 23.0 0.0 6.4e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KEY66529.1 - 0.00023 20.2 1.5 0.0042 16.0 0.3 2.7 2 1 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KEY66529.1 - 0.00079 18.6 0.1 0.0014 17.8 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 KEY66529.1 - 0.063 12.3 0.0 7.4 5.5 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KEY66529.1 - 0.096 11.9 0.1 0.92 8.7 0.0 2.1 1 1 1 2 2 2 0 Histidine biosynthesis protein DHO_dh PF01180.16 KEY66529.1 - 0.12 11.3 0.0 1.4 7.7 0.0 2.0 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DUF4202 PF13875.1 KEY66530.1 - 8.6e-71 237.3 0.0 9.8e-71 237.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) 14-3-3 PF00244.15 KEY66532.1 - 8.1e-08 31.6 0.0 3.2e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 14-3-3 protein Sterol-sensing PF12349.3 KEY66534.1 - 3.3e-37 127.3 8.2 3.3e-37 127.3 5.7 1.9 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KEY66534.1 - 6.9e-09 34.2 6.2 1e-08 33.6 4.3 1.1 1 0 0 1 1 1 1 Patched family Cupin_8 PF13621.1 KEY66535.1 - 4.2e-62 209.9 0.1 5.9e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KEY66535.1 - 6.9e-06 25.5 0.1 0.0014 17.9 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 KEY66535.1 - 0.033 14.4 0.0 0.46 10.7 0.0 2.4 2 0 0 2 2 2 0 JmjC domain, hydroxylase Spb1_C PF07780.7 KEY66536.1 - 1.1e-73 247.2 21.0 1.1e-73 247.2 14.6 3.4 3 1 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 KEY66536.1 - 4.1e-57 192.1 2.5 4.1e-57 192.1 1.7 4.2 3 1 1 4 4 4 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 KEY66536.1 - 8e-55 185.6 0.0 1.8e-54 184.4 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Dynamin_N PF00350.18 KEY66537.1 - 1.1e-42 145.6 0.0 2.1e-42 144.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KEY66537.1 - 1.9e-11 43.3 0.3 3.9e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 KEY66537.1 - 0.0005 20.0 0.2 0.0068 16.3 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KEY66537.1 - 0.0036 17.7 0.0 0.008 16.6 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 KEY66537.1 - 0.02 14.8 2.3 0.43 10.5 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_21 PF13304.1 KEY66537.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cation_efflux PF01545.16 KEY66538.1 - 1.1e-31 109.9 11.1 1.5e-31 109.5 7.7 1.1 1 0 0 1 1 1 1 Cation efflux family Ferrochelatase PF00762.14 KEY66538.1 - 0.0092 14.9 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Ferrochelatase zf-MYND PF01753.13 KEY66540.1 - 1.5e-07 31.1 20.7 3.9e-07 29.8 14.3 1.7 1 0 0 1 1 1 1 MYND finger Ebp2 PF05890.7 KEY66541.1 - 6.5e-92 307.6 15.0 6.5e-92 307.6 10.4 1.9 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Cyanate_lyase PF02560.9 KEY66542.1 - 4.9e-32 109.2 0.0 7.1e-32 108.7 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Sigma70_r4_2 PF08281.7 KEY66542.1 - 0.00012 21.4 0.0 0.0032 16.9 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_31 PF13560.1 KEY66542.1 - 0.002 18.2 0.0 0.0032 17.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain PP1_inhibitor PF05361.7 KEY66542.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor B-block_TFIIIC PF04182.7 KEY66543.1 - 5.1e-14 51.8 0.0 3.1e-13 49.3 0.0 2.2 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC HTH_27 PF13463.1 KEY66543.1 - 0.032 14.5 0.2 0.11 12.8 0.1 1.9 1 0 0 1 1 1 0 Winged helix DNA-binding domain UQ_con PF00179.21 KEY66544.1 - 4.4e-22 78.0 0.0 6.9e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KEY66544.1 - 0.0052 16.6 0.0 0.0085 15.9 0.0 1.4 1 0 0 1 1 1 1 RWD domain NADH_B2 PF14813.1 KEY66545.1 - 0.072 12.7 0.0 0.078 12.6 0.0 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 P5-ATPase PF12409.3 KEY66546.1 - 3.5e-37 126.8 0.1 1.2e-36 125.1 0.0 2.0 2 0 0 2 2 2 1 P5-type ATPase cation transporter HAD PF12710.2 KEY66546.1 - 1.4e-31 110.1 0.0 2.8e-31 109.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KEY66546.1 - 5.4e-26 91.0 0.0 1.3e-25 89.8 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KEY66546.1 - 1.3e-17 64.9 0.0 3e-16 60.4 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEY66546.1 - 0.0019 17.6 0.0 0.0047 16.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KEY66546.1 - 0.019 14.9 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEY66546.1 - 0.083 12.4 0.5 0.95 8.9 0.0 2.4 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase NAP PF00956.13 KEY66547.1 - 1.2e-86 289.8 5.1 1.2e-86 289.8 3.5 1.9 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Myosin_head PF00063.16 KEY66548.1 - 3.1e-241 802.2 0.2 3.1e-241 802.2 0.1 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 KEY66548.1 - 2.6e-34 117.2 3.5 2.6e-34 117.2 2.4 2.2 2 0 0 2 2 1 1 DIL domain IQ PF00612.22 KEY66548.1 - 1e-13 49.5 36.7 6.5e-05 22.2 1.4 6.4 6 0 0 6 6 6 5 IQ calmodulin-binding motif Reo_sigmaC PF04582.7 KEY66548.1 - 6.9e-05 22.1 3.7 8.2e-05 21.9 1.7 1.7 2 0 0 2 2 2 1 Reovirus sigma C capsid protein AAA_22 PF13401.1 KEY66548.1 - 0.0012 18.9 0.0 0.0071 16.4 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KEY66548.1 - 0.011 15.7 0.3 0.14 12.1 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain Flagellin_N PF00669.15 KEY66548.1 - 0.015 15.1 8.6 0.065 13.0 5.7 2.3 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region AAA_19 PF13245.1 KEY66548.1 - 0.02 14.6 0.5 0.061 13.0 0.0 2.1 2 0 0 2 2 1 0 Part of AAA domain AAA_10 PF12846.2 KEY66548.1 - 0.031 13.7 1.8 0.16 11.3 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain Myosin_N PF02736.14 KEY66548.1 - 0.056 13.1 0.1 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Baculo_PEP_C PF04513.7 KEY66548.1 - 0.2 11.4 7.0 0.21 11.3 3.0 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.1 KEY66548.1 - 1 8.4 29.8 1.5 7.9 6.3 2.5 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 KEY66548.1 - 1.4 9.0 10.6 1.9 8.6 5.8 2.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family IncA PF04156.9 KEY66548.1 - 1.8 8.0 29.0 4.1 6.9 10.8 2.6 1 1 1 2 2 2 0 IncA protein DUF972 PF06156.8 KEY66548.1 - 2.5 8.4 19.7 3.7 7.9 3.4 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Tropomyosin_1 PF12718.2 KEY66548.1 - 3.3 7.5 32.3 0.86 9.4 8.7 2.5 1 1 1 2 2 2 0 Tropomyosin like TPD52 PF04201.10 KEY66548.1 - 6.9 6.3 16.5 4.5 6.9 0.6 2.8 2 0 0 2 2 2 0 Tumour protein D52 family CENP-F_leu_zip PF10473.4 KEY66548.1 - 8 6.3 31.4 1.6 8.5 4.7 2.6 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_18 PF13238.1 KEY66549.1 - 6.3e-28 97.6 0.8 1.4e-27 96.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEY66549.1 - 1.1e-15 58.5 0.8 2.8e-15 57.2 0.6 1.7 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 KEY66549.1 - 2.3e-06 27.5 0.1 0.0018 18.1 0.0 2.3 1 1 1 2 2 2 2 Adenylate kinase AAA_33 PF13671.1 KEY66549.1 - 5.2e-06 26.3 0.2 0.0046 16.8 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KEY66549.1 - 2e-05 24.6 0.2 9.4e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 KEY66549.1 - 6.8e-05 22.3 0.2 0.29 10.4 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA PF00004.24 KEY66549.1 - 7.3e-05 22.9 0.0 0.001 19.2 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 KEY66549.1 - 0.00033 20.4 0.0 0.0007 19.3 0.0 1.7 2 0 0 2 2 2 1 NTPase AAA_22 PF13401.1 KEY66549.1 - 0.0007 19.7 0.7 0.003 17.6 0.5 2.0 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 KEY66549.1 - 0.00098 18.4 0.1 0.0028 16.9 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 SKI PF01202.17 KEY66549.1 - 0.0011 18.8 0.6 0.025 14.4 0.4 2.1 1 1 0 1 1 1 1 Shikimate kinase AAA_16 PF13191.1 KEY66549.1 - 0.0029 17.6 0.3 0.0058 16.6 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain Cytidylate_kin2 PF13189.1 KEY66549.1 - 0.0071 16.2 0.1 0.013 15.4 0.0 1.7 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_5 PF07728.9 KEY66549.1 - 0.0072 16.0 0.1 0.029 14.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.4 KEY66549.1 - 0.013 14.1 0.0 0.022 13.4 0.0 1.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 KEY66549.1 - 0.013 14.9 0.4 0.025 14.0 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 KEY66549.1 - 0.013 14.9 0.0 0.039 13.3 0.0 1.7 1 1 1 2 2 2 0 AAA-like domain AAA_24 PF13479.1 KEY66549.1 - 0.015 14.9 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KEY66549.1 - 0.017 15.0 0.1 0.064 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEY66549.1 - 0.018 15.2 0.0 0.038 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase MobB PF03205.9 KEY66549.1 - 0.019 14.6 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 KEY66549.1 - 0.02 14.4 0.5 0.041 13.4 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.12 KEY66549.1 - 0.027 13.8 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.13 KEY66549.1 - 0.029 13.8 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 KEY66549.1 - 0.032 13.9 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain SRP54 PF00448.17 KEY66549.1 - 0.05 13.0 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ArgK PF03308.11 KEY66549.1 - 0.058 12.1 0.0 0.1 11.3 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_3 PF07726.6 KEY66549.1 - 0.071 12.7 0.2 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ham1p_like PF01725.11 KEY66550.1 - 1.4e-46 158.2 0.0 1.7e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_C78 PF07910.8 KEY66551.1 - 3.2e-64 216.0 0.0 3.7e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C47 PF05543.8 KEY66551.1 - 0.035 13.5 0.0 0.4 10.0 0.0 2.4 2 1 1 3 3 3 0 Staphopain peptidase C47 tRNA-synt_2b PF00587.20 KEY66552.1 - 4.6e-34 117.4 0.0 7.5e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KEY66552.1 - 3.3e-17 62.4 7.6 6.5e-17 61.5 5.2 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain SPT16 PF08644.6 KEY66552.1 - 0.37 10.6 2.9 0.47 10.2 1.0 1.8 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Ras PF00071.17 KEY66553.1 - 1e-41 141.9 0.1 1.6e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 Ras family WAPL PF07814.8 KEY66553.1 - 8.1e-13 47.8 1.3 8.5e-10 37.8 0.2 2.4 2 0 0 2 2 2 2 Wings apart-like protein regulation of heterochromatin Miro PF08477.8 KEY66553.1 - 8.6e-13 48.8 0.1 2e-12 47.6 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KEY66553.1 - 0.00012 21.9 0.2 0.00031 20.6 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.16 KEY66553.1 - 0.00059 19.1 0.0 0.00094 18.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KEY66553.1 - 0.0021 17.3 0.0 0.0039 16.4 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 KEY66553.1 - 0.085 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain UPRTase PF14681.1 KEY66554.1 - 7.1e-78 260.5 0.0 9.1e-78 260.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KEY66554.1 - 0.0001 22.0 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 KEY66554.1 - 0.12 12.0 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Elf1 PF05129.8 KEY66555.1 - 1.2e-28 98.5 0.4 1.5e-28 98.2 0.3 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Cys_rich_CWC PF14375.1 KEY66555.1 - 0.056 13.3 0.5 0.11 12.3 0.3 1.5 1 0 0 1 1 1 0 Cysteine-rich CWC Ribosomal_S3Ae PF01015.13 KEY66556.1 - 4.2e-82 274.1 4.5 5.5e-82 273.8 3.1 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family mRNA_cap_C PF03919.10 KEY66556.1 - 0.019 15.2 0.1 0.054 13.8 0.0 1.9 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain Erythro-docking PF09277.6 KEY66556.1 - 0.096 12.3 0.3 3.5 7.3 0.0 2.6 2 0 0 2 2 2 0 Erythronolide synthase, docking Syntaxin PF00804.20 KEY66556.1 - 0.1 12.7 0.7 0.85 9.8 0.0 2.5 2 1 0 3 3 3 0 Syntaxin Abhydrolase_6 PF12697.2 KEY66557.1 - 1.2e-32 113.5 0.0 1.6e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY66557.1 - 1.1e-18 67.6 0.0 2.5e-18 66.4 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY66557.1 - 6.9e-15 55.0 0.0 1.2e-14 54.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KEY66557.1 - 2.6e-08 33.7 0.1 3.6e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 KEY66557.1 - 2.5e-07 31.1 0.0 3.1e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.15 KEY66557.1 - 0.0017 17.7 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 KEY66557.1 - 0.0091 15.8 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 KEY66557.1 - 0.029 12.8 0.0 0.079 11.4 0.0 1.6 2 0 0 2 2 2 0 Ndr family Lipase_3 PF01764.20 KEY66557.1 - 0.075 12.6 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.10 KEY66557.1 - 0.09 11.7 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase WCCH PF03716.9 KEY66558.1 - 0.067 12.6 6.1 0.4 10.1 0.5 2.5 2 0 0 2 2 2 0 WCCH motif WD40 PF00400.27 KEY66559.1 - 1.6e-48 160.8 16.7 1.3e-08 34.3 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 KEY66559.1 - 5.8e-08 32.3 0.1 5.8e-08 32.3 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KEY66559.1 - 4.3e-06 26.2 0.1 1.4e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 KEY66559.1 - 1.1e-05 23.8 0.7 0.62 8.1 0.0 4.2 2 1 3 5 5 5 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KEY66559.1 - 0.0025 17.2 0.1 0.018 14.5 0.0 2.3 2 1 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 KEY66559.1 - 0.0079 14.5 0.1 0.016 13.4 0.1 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 KEY66559.1 - 0.0093 14.7 1.8 0.31 9.7 0.2 2.8 2 1 0 2 2 2 1 Nup133 N terminal like FlaG PF03646.10 KEY66559.1 - 0.02 15.0 0.0 0.48 10.5 0.0 2.8 3 0 0 3 3 3 0 FlaG protein Pectate_lyase_3 PF12708.2 KEY66560.1 - 3.7e-84 282.3 17.2 5.2e-70 236.0 5.6 2.9 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KEY66560.1 - 4e-05 22.9 2.6 0.099 12.1 0.2 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 KEY66560.1 - 0.0012 18.5 12.2 0.0012 18.5 8.5 3.3 3 1 0 3 3 3 1 Right handed beta helix region Scs3p PF10261.4 KEY66561.1 - 8.8e-65 218.0 7.1 1.1e-64 217.7 4.9 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM BMC PF00936.14 KEY66561.1 - 0.014 15.0 0.1 0.036 13.7 0.0 1.6 1 0 0 1 1 1 0 BMC domain ATP_transf PF09830.4 KEY66562.1 - 4.6e-16 58.3 0.0 7.4e-16 57.6 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 KEY66562.1 - 0.026 15.0 0.0 0.051 14.0 0.0 1.4 1 0 0 1 1 1 0 HIT domain PBP1_TM PF14812.1 KEY66563.1 - 0.21 11.9 5.2 0.52 10.6 3.6 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Man-6-P_recep PF02157.10 KEY66564.1 - 1.9e-08 33.6 0.0 2.4e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 KEY66564.1 - 2.6e-05 24.0 0.1 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 KEY66564.1 - 5.1e-05 22.6 0.1 0.00026 20.3 0.1 2.0 1 1 0 1 1 1 1 Autophagy-related protein 27 DUF3311 PF11755.3 KEY66564.1 - 0.02 14.4 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) ERG4_ERG24 PF01222.12 KEY66565.1 - 1.3e-158 528.0 3.7 1.6e-158 527.7 2.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KEY66565.1 - 3e-05 23.4 1.1 6.2e-05 22.4 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Glyco_hydro_3 PF00933.16 KEY66566.1 - 2.1e-90 302.7 0.0 4.3e-90 301.7 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY66566.1 - 1.8e-48 165.0 0.1 3.7e-47 160.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEY66566.1 - 6.7e-18 64.4 0.0 1.4e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF4554 PF15091.1 KEY66567.1 - 3.8 6.1 8.3 0.35 9.5 1.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4554) Granulin PF00396.13 KEY66569.1 - 1.7 8.8 17.6 3.1 7.9 1.4 2.5 1 1 1 2 2 2 0 Granulin HET PF06985.6 KEY66570.1 - 5.1e-18 65.5 0.0 9.8e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Prominin PF05478.6 KEY66570.1 - 0.00076 17.1 0.4 0.0011 16.6 0.3 1.1 1 0 0 1 1 1 1 Prominin ADH_zinc_N PF00107.21 KEY66571.1 - 4e-31 107.2 1.2 5.9e-31 106.7 0.2 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY66571.1 - 3.3e-14 53.8 0.0 1.1e-13 52.2 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY66571.1 - 8.5e-12 44.8 0.0 1.5e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 KEY66571.1 - 0.00055 19.9 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 KEY66571.1 - 0.014 14.9 0.1 0.024 14.1 0.1 1.6 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase WCCH PF03716.9 KEY66572.1 - 0.03 13.7 10.6 0.8 9.2 0.9 3.3 3 0 0 3 3 3 0 WCCH motif Gly_transf_sug PF04488.10 KEY66573.1 - 1.1e-06 28.9 0.0 1.7e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KEY66573.1 - 0.0013 17.2 0.1 0.0017 16.9 0.0 1.1 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain HemN_C PF06969.11 KEY66574.1 - 0.01 15.8 0.0 0.027 14.5 0.0 1.6 2 0 0 2 2 2 0 HemN C-terminal domain AMP-binding PF00501.23 KEY66575.1 - 3.4e-63 213.4 0.0 5.9e-63 212.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 KEY66575.1 - 3.6e-15 55.9 0.0 8.7e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.19 KEY66575.1 - 1.2e-05 24.5 5.4 0.057 12.9 0.0 6.3 7 1 0 7 7 7 1 Bacterial transferase hexapeptide (six repeats) GH3 PF03321.8 KEY66575.1 - 0.062 11.8 0.0 2.8 6.3 0.0 2.1 2 0 0 2 2 2 0 GH3 auxin-responsive promoter RRM_1 PF00076.17 KEY66576.1 - 6.6e-27 92.9 1.4 3e-12 45.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY66576.1 - 8.1e-22 76.8 0.1 1.2e-11 44.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY66576.1 - 4.8e-19 68.0 0.3 1.5e-08 34.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Selenoprotein_S PF06936.6 KEY66576.1 - 0.024 14.1 0.2 0.033 13.7 0.1 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) ATP-synt_D PF01813.12 KEY66577.1 - 6.7e-55 185.6 3.4 1.7e-54 184.3 2.3 1.6 1 1 0 1 1 1 1 ATP synthase subunit D Terminase_2 PF03592.11 KEY66577.1 - 0.057 13.7 8.7 2.9 8.1 6.0 2.2 1 1 0 1 1 1 0 Terminase small subunit SYCE1 PF15233.1 KEY66577.1 - 0.11 12.4 2.9 0.29 11.0 1.7 1.8 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 GvpL_GvpF PF06386.6 KEY66577.1 - 0.35 10.4 4.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Suf PF05843.9 KEY66578.1 - 3.1e-10 40.2 6.6 0.063 13.0 0.0 5.8 4 1 1 6 6 6 2 Suppressor of forked protein (Suf) TPR_12 PF13424.1 KEY66578.1 - 3.2e-10 39.7 3.6 0.68 9.9 0.0 7.2 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEY66578.1 - 1.5e-07 31.3 13.0 2.2 9.1 0.0 9.4 9 2 2 11 11 10 2 Tetratricopeptide repeat TPR_15 PF13429.1 KEY66578.1 - 3.1e-06 26.4 5.2 3.9e-05 22.8 0.6 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 KEY66578.1 - 1.8e-05 24.4 8.3 1.3 8.7 0.1 6.7 7 0 0 7 7 7 2 Mad3/BUB1 homology region 1 TPR_11 PF13414.1 KEY66578.1 - 2.2e-05 23.9 6.0 3.2 7.4 0.0 6.7 8 0 0 8 8 8 2 TPR repeat NRDE-2 PF08424.5 KEY66578.1 - 0.00098 18.0 8.3 0.12 11.2 0.3 6.0 2 2 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_16 PF13432.1 KEY66578.1 - 0.0063 17.1 10.6 0.27 11.9 0.0 6.4 8 0 0 8 8 7 1 Tetratricopeptide repeat RPN7 PF10602.4 KEY66578.1 - 0.0096 15.3 0.3 0.042 13.2 0.1 2.3 3 1 0 3 3 3 1 26S proteasome subunit RPN7 PPR_3 PF13812.1 KEY66578.1 - 0.026 14.7 0.0 0.26 11.6 0.0 2.8 2 0 0 2 2 1 0 Pentatricopeptide repeat domain TPR_8 PF13181.1 KEY66578.1 - 0.027 14.2 3.7 3.7 7.5 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat PolyA_pol PF01743.15 KEY66580.1 - 1.2e-26 93.4 0.2 2.3e-26 92.4 0.1 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 KEY66580.1 - 2.1e-09 36.7 0.0 5.5e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 KEY66580.1 - 0.00085 19.1 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative DUF2454 PF10521.4 KEY66581.1 - 3.1e-59 200.3 0.3 1.1e-58 198.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2454) Syja_N PF02383.13 KEY66582.1 - 8.4e-90 300.7 0.0 1.9e-89 299.6 0.0 1.5 2 0 0 2 2 2 1 SacI homology domain Sec7 PF01369.15 KEY66583.1 - 3.1e-58 196.5 0.0 6.3e-58 195.5 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KEY66583.1 - 3.4e-16 59.1 0.0 2.4e-10 40.0 0.1 2.9 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1258 PF06869.7 KEY66583.1 - 0.22 10.5 0.0 0.44 9.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) Anp1 PF03452.9 KEY66584.1 - 1.4e-121 404.7 1.6 2e-121 404.2 0.0 2.0 2 0 0 2 2 2 1 Anp1 DUF2146 PF10220.4 KEY66584.1 - 2.2 6.1 7.0 2.9 5.7 4.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) RNase_PH PF01138.16 KEY66585.1 - 2.5e-26 92.5 0.0 5.1e-26 91.5 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Glyco_hydro_2_N PF02837.13 KEY66586.1 - 3.2e-08 33.2 0.1 7.4e-08 32.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KEY66586.1 - 1.7e-05 23.8 0.0 3.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KEY66586.1 - 3.3e-05 24.2 0.1 0.00018 21.9 0.0 2.3 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 zf-C3HC4_3 PF13920.1 KEY66587.1 - 2.8e-07 30.0 13.2 4.6e-07 29.3 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SDA1 PF05285.7 KEY66587.1 - 0.099 11.9 1.4 0.15 11.3 1.0 1.2 1 0 0 1 1 1 0 SDA1 FAM24 PF15193.1 KEY66587.1 - 2.4 8.4 9.1 4.8 7.4 6.3 1.5 1 0 0 1 1 1 0 FAM24 family tRNA_int_endo PF01974.12 KEY66588.1 - 1.4e-10 40.8 0.0 2.9e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain B PF02216.11 KEY66588.1 - 0.00066 19.3 0.1 0.0014 18.3 0.1 1.6 1 0 0 1 1 1 1 B domain PAXNEB PF05625.6 KEY66589.1 - 1.1e-97 327.1 0.0 1.2e-97 326.9 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein RNA_pol_Rpb8 PF03870.10 KEY66590.1 - 7.8e-38 129.7 0.0 8.8e-38 129.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 NUDIX PF00293.23 KEY66591.1 - 4.9e-10 39.1 0.0 8.4e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF775 PF05603.7 KEY66592.1 - 2.3e-48 164.4 0.0 4.2e-48 163.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF775) DEC-1_N PF04625.8 KEY66592.1 - 0.018 13.7 2.4 0.028 13.0 1.6 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region GDA1_CD39 PF01150.12 KEY66593.1 - 3.5e-98 328.9 0.0 5e-98 328.4 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family zf-RING_5 PF14634.1 KEY66594.1 - 4.9e-07 29.3 5.0 7.8e-07 28.7 3.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEY66594.1 - 0.00082 19.3 1.9 0.0022 17.9 1.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DivIVA PF05103.8 KEY66594.1 - 0.0025 17.8 5.9 0.004 17.2 4.1 1.3 1 0 0 1 1 1 1 DivIVA protein CCDC14 PF15254.1 KEY66594.1 - 0.0033 15.8 6.3 0.0046 15.3 4.4 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 14 Tropomyosin_1 PF12718.2 KEY66594.1 - 0.0036 17.1 7.6 0.0057 16.5 5.3 1.2 1 0 0 1 1 1 1 Tropomyosin like zf-C3HC4_3 PF13920.1 KEY66594.1 - 0.0053 16.4 4.1 0.009 15.6 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CCDC155 PF14662.1 KEY66594.1 - 0.0069 15.9 7.7 0.01 15.4 5.4 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 zf-C3HC4 PF00097.20 KEY66594.1 - 0.0075 15.9 4.2 0.014 15.0 2.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEY66594.1 - 0.0077 16.0 5.5 0.015 15.1 3.8 1.5 1 0 0 1 1 1 1 Ring finger domain Ax_dynein_light PF10211.4 KEY66594.1 - 0.061 13.1 4.2 0.1 12.4 2.9 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain TMF_DNA_bd PF12329.3 KEY66594.1 - 0.1 12.4 2.2 0.2 11.4 1.3 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DZR PF12773.2 KEY66594.1 - 0.13 12.0 1.5 0.28 11.0 1.0 1.5 1 0 0 1 1 1 0 Double zinc ribbon APG6 PF04111.7 KEY66594.1 - 0.16 10.9 7.3 0.22 10.5 5.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 PEP-utilisers_N PF05524.8 KEY66594.1 - 0.19 11.5 3.1 0.33 10.7 2.1 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal zf-C3HC4_4 PF15227.1 KEY66594.1 - 0.32 10.8 2.3 0.68 9.8 1.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KEY66594.1 - 0.43 10.3 3.0 0.95 9.2 2.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Spc24 PF08286.6 KEY66594.1 - 0.56 9.9 6.5 1.4 8.6 4.6 1.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DivIC PF04977.10 KEY66594.1 - 0.66 9.5 5.1 2 7.9 3.5 1.9 1 1 0 1 1 1 0 Septum formation initiator GrpE PF01025.14 KEY66594.1 - 1.1 8.7 6.6 2.6 7.5 4.6 1.5 1 1 1 2 2 2 0 GrpE CENP-H PF05837.7 KEY66594.1 - 1.5 9.0 6.0 2.4 8.3 3.9 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) IncA PF04156.9 KEY66594.1 - 1.8 8.1 8.6 2.7 7.5 5.9 1.2 1 0 0 1 1 1 0 IncA protein zf-RING_3 PF14369.1 KEY66594.1 - 8 6.5 7.3 1.8 8.5 1.8 2.1 1 1 1 2 2 2 0 zinc-finger Lipase_GDSL_2 PF13472.1 KEY66595.1 - 7.9e-15 55.4 1.3 1.2e-14 54.8 0.9 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KEY66595.1 - 9.1e-10 38.7 0.8 1.5e-09 38.0 0.6 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SurA_N_3 PF13624.1 KEY66595.1 - 0.071 13.0 0.1 0.51 10.3 0.0 2.0 1 1 1 2 2 2 0 SurA N-terminal domain Ribosomal_L28e PF01778.12 KEY66595.1 - 0.089 13.1 0.1 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal L28e protein family Fungal_trans PF04082.13 KEY66596.1 - 4.6e-27 94.5 0.0 1e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY66596.1 - 2.8e-07 30.3 12.6 5.1e-07 29.4 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BatA PF07584.6 KEY66596.1 - 0.067 13.3 2.1 24 5.2 0.0 4.1 4 0 0 4 4 4 0 Aerotolerance regulator N-terminal ThiF PF00899.16 KEY66597.1 - 2.5e-07 30.5 0.0 5.8e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 ThiF family adh_short PF00106.20 KEY66598.1 - 2e-34 118.9 0.0 2.9e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY66598.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY66598.1 - 8.5e-13 48.6 0.0 1e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 KEY66598.1 - 0.0019 17.2 0.0 0.0039 16.2 0.0 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 KEY66598.1 - 0.0019 17.1 0.0 0.0055 15.6 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 KEY66598.1 - 0.0036 17.0 0.7 0.012 15.3 0.1 2.1 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KEY66598.1 - 0.0045 16.4 0.2 0.0091 15.4 0.0 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Pribosyltran_N PF13793.1 KEY66599.1 - 2.8e-42 143.0 0.0 1.3e-40 137.7 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KEY66599.1 - 4.4e-33 114.5 0.0 1.3e-27 96.7 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KEY66599.1 - 2e-05 24.3 0.1 0.0064 16.2 0.0 2.8 3 0 0 3 3 3 2 Phosphoribosyl transferase domain XPG_I_2 PF12813.2 KEY66600.1 - 5.5e-47 160.3 0.0 1.6e-46 158.8 0.0 1.7 1 1 1 2 2 2 1 XPG domain containing XPG_I PF00867.13 KEY66600.1 - 0.0026 17.7 0.0 0.019 15.0 0.0 2.2 2 0 0 2 2 2 1 XPG I-region PAP_assoc PF03828.14 KEY66601.1 - 1.4e-18 66.5 0.0 1.1e-17 63.6 0.0 2.3 1 1 0 1 1 1 1 Cid1 family poly A polymerase Retrotrans_gag PF03732.12 KEY66601.1 - 0.03 14.3 1.2 13 5.8 0.0 3.3 2 1 0 3 3 3 0 Retrotransposon gag protein PAP_central PF04928.12 KEY66601.1 - 0.088 11.6 0.0 4.4 6.0 0.0 2.4 2 0 0 2 2 2 0 Poly(A) polymerase central domain TFIIF_alpha PF05793.7 KEY66602.1 - 0.00061 18.2 47.4 0.00094 17.6 32.3 1.6 1 1 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Bud13 PF09736.4 KEY66603.1 - 1.8e-47 161.2 8.6 1.8e-47 161.2 5.9 2.7 2 1 1 3 3 3 1 Pre-mRNA-splicing factor of RES complex TRAPPC-Trs85 PF12739.2 KEY66604.1 - 3.3e-107 358.7 0.0 7.3e-107 357.5 0.0 1.5 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Snf7 PF03357.16 KEY66605.1 - 8.7e-21 74.0 21.5 1.4e-20 73.3 14.9 1.4 1 0 0 1 1 1 1 Snf7 DUF4355 PF14265.1 KEY66605.1 - 0.066 13.1 29.1 0.11 12.4 11.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Herpes_UL87 PF03043.9 KEY66605.1 - 0.23 9.8 3.3 0.29 9.4 2.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family zf-C3HC4 PF00097.20 KEY66606.1 - 2e-08 33.7 8.6 2e-08 33.7 6.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEY66606.1 - 1.3e-06 27.9 7.2 1.3e-06 27.9 5.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEY66606.1 - 1.5e-06 28.0 9.8 1.5e-06 28.0 6.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY66606.1 - 2.7e-06 26.9 8.8 2.7e-06 26.9 6.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KEY66606.1 - 5.3e-06 26.2 8.2 5.3e-06 26.2 5.7 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KEY66606.1 - 7.2e-06 25.7 9.7 7.2e-06 25.7 6.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 KEY66606.1 - 2.4e-05 23.9 2.7 2.4e-05 23.9 1.9 2.9 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_6 PF14835.1 KEY66606.1 - 4.6e-05 23.1 2.5 4.6e-05 23.1 1.7 1.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 KEY66606.1 - 0.0048 16.9 2.7 0.0048 16.9 1.9 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger SAP PF02037.22 KEY66606.1 - 0.033 13.7 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 SAP domain Mob_synth_C PF06463.8 KEY66606.1 - 0.089 12.4 0.9 0.18 11.4 0.6 1.4 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C Rad50_zn_hook PF04423.9 KEY66606.1 - 0.3 10.6 1.9 17 4.9 0.1 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.1 KEY66606.1 - 0.46 10.1 11.0 0.16 11.6 4.2 2.5 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain PRCC PF10253.4 KEY66606.1 - 0.59 10.7 4.7 7.1 7.2 0.0 3.0 2 2 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting zf-Nse PF11789.3 KEY66606.1 - 2 7.9 10.1 0.078 12.5 2.6 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit CDC27 PF09507.5 KEY66607.1 - 5.6e-91 305.9 28.2 9e-91 305.2 19.5 1.3 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF4366 PF14283.1 KEY66607.1 - 0.18 11.2 14.6 1.6 8.1 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF1682 PF07946.9 KEY66607.1 - 1.5 7.6 7.7 0.44 9.3 2.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Aminotran_1_2 PF00155.16 KEY66608.1 - 1.2e-25 90.2 0.0 1.5e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KEY66608.1 - 0.0089 14.6 0.0 0.022 13.3 0.0 1.6 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DUF1237 PF06824.6 KEY66609.1 - 3.1e-175 582.8 0.0 3.6e-175 582.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) CagY_M PF07337.6 KEY66609.1 - 0.11 11.9 0.2 0.25 10.8 0.1 1.5 1 0 0 1 1 1 0 DC-EC Repeat MOZ_SAS PF01853.13 KEY66610.1 - 1.2e-85 285.5 0.4 1.6e-85 285.1 0.3 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 KEY66610.1 - 1.7e-18 66.0 0.1 2.5e-17 62.3 0.0 2.9 3 0 0 3 3 3 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 KEY66610.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family RNase_T PF00929.19 KEY66611.1 - 2.9e-24 86.2 0.0 4.5e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 KEY66611.1 - 0.0075 15.7 0.0 0.018 14.5 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease RNase_H2_suC PF08615.6 KEY66612.1 - 6.3e-25 87.6 0.0 8.4e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) MCM PF00493.18 KEY66613.1 - 5e-137 456.1 1.0 8.5e-137 455.3 0.5 1.6 1 1 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KEY66613.1 - 1.4e-21 77.2 0.8 4.8e-21 75.4 0.0 2.4 3 1 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 KEY66613.1 - 2.6e-07 30.0 0.0 7.8e-07 28.4 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KEY66613.1 - 0.00082 18.8 0.0 0.0025 17.3 0.0 1.8 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 KEY66613.1 - 0.002 17.7 0.2 0.0049 16.4 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2360 PF10152.4 KEY66613.1 - 0.0046 17.2 0.4 0.064 13.5 0.1 2.6 2 1 0 2 2 2 1 Predicted coiled-coil domain-containing protein (DUF2360) AAA_5 PF07728.9 KEY66613.1 - 0.03 14.0 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) F1F0-ATPsyn_F PF10791.4 KEY66615.1 - 1.9e-40 136.9 0.3 2.1e-40 136.8 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 KEY66615.1 - 0.0029 17.6 0.3 0.0037 17.2 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.7 KEY66616.1 - 3.3e-35 119.9 0.9 4.9e-35 119.4 0.6 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region CLTH PF10607.4 KEY66617.1 - 5.6e-30 103.9 0.1 7.5e-30 103.5 0.1 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KEY66617.1 - 1.5e-06 27.7 0.0 3.6e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 LisH RRM_1 PF00076.17 KEY66618.1 - 1.7e-08 33.9 0.0 3.9e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY66618.1 - 1.1e-06 28.3 0.0 2.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEY66618.1 - 7.1e-05 22.4 0.0 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 KEY66618.1 - 0.00027 20.5 0.5 0.00056 19.5 0.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_6 PF14259.1 KEY66618.1 - 0.0003 20.6 0.0 0.00061 19.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PRK PF00485.13 KEY66619.1 - 1.2e-56 191.3 0.0 1.7e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 KEY66619.1 - 1.9e-39 135.0 0.0 3.3e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 KEY66619.1 - 1.1e-10 42.3 0.0 3.4e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 KEY66619.1 - 4.7e-06 26.3 0.0 9.6e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.1 KEY66619.1 - 4.7e-06 26.9 0.0 1.6e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEY66619.1 - 6.9e-06 25.9 0.0 5e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEY66619.1 - 0.00019 21.4 0.2 0.0052 16.7 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 KEY66619.1 - 0.00079 18.5 0.0 0.0021 17.2 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin NB-ARC PF00931.17 KEY66619.1 - 0.0021 16.9 0.0 0.006 15.4 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_29 PF13555.1 KEY66619.1 - 0.0023 17.4 0.1 0.0065 15.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KEY66619.1 - 0.0026 18.0 0.1 0.0068 16.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter MobB PF03205.9 KEY66619.1 - 0.0032 17.1 0.0 0.0091 15.7 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KEY66619.1 - 0.0042 16.7 0.1 0.014 15.0 0.1 1.9 1 0 0 1 1 1 1 NACHT domain DUF87 PF01935.12 KEY66619.1 - 0.0061 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_22 PF13401.1 KEY66619.1 - 0.0069 16.5 0.0 0.027 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KEY66619.1 - 0.0078 15.1 0.0 0.022 13.6 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF258 PF03193.11 KEY66619.1 - 0.014 14.5 0.0 0.029 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 KEY66619.1 - 0.015 14.7 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.24 KEY66619.1 - 0.019 15.1 0.0 0.058 13.5 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KEY66619.1 - 0.027 13.8 0.1 0.068 12.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 KEY66619.1 - 0.027 14.6 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Pribosyltran PF00156.22 KEY66619.1 - 0.029 14.1 0.1 0.53 10.0 0.0 2.7 3 0 0 3 3 3 0 Phosphoribosyl transferase domain APS_kinase PF01583.15 KEY66619.1 - 0.032 13.8 0.1 0.11 12.1 0.0 2.0 2 0 0 2 2 1 0 Adenylylsulphate kinase AAA_5 PF07728.9 KEY66619.1 - 0.05 13.3 0.0 0.34 10.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) SKI PF01202.17 KEY66619.1 - 0.055 13.3 0.0 1.1 9.0 0.0 2.8 3 0 0 3 3 3 0 Shikimate kinase AAA_10 PF12846.2 KEY66619.1 - 0.06 12.7 0.6 0.1 12.0 0.1 1.6 2 0 0 2 2 2 0 AAA-like domain AAA_28 PF13521.1 KEY66619.1 - 0.13 12.2 0.0 0.35 10.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain CobU PF02283.11 KEY66619.1 - 0.13 11.6 0.1 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Arch_ATPase PF01637.13 KEY66619.1 - 0.13 11.8 0.1 2.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase Pyr_redox_2 PF07992.9 KEY66620.1 - 9.1e-23 81.1 0.0 1.3e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY66620.1 - 1.7e-14 53.9 0.0 1.1e-10 41.7 0.0 3.6 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 KEY66620.1 - 2.7e-07 29.4 0.1 7.1e-07 28.0 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KEY66620.1 - 1.3e-06 27.7 0.4 4.4e-06 26.1 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 KEY66620.1 - 1e-05 25.5 1.3 1.7e-05 24.8 0.2 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KEY66620.1 - 1.2e-05 24.4 0.8 6.8e-05 22.0 0.3 2.2 2 0 0 2 2 2 1 EF hand Pyr_redox_3 PF13738.1 KEY66620.1 - 0.0021 18.1 0.0 0.69 9.9 0.0 2.9 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase SWIRM PF04433.12 KEY66620.1 - 0.042 13.9 0.1 12 6.0 0.0 2.6 2 1 0 2 2 2 0 SWIRM domain FAD_binding_2 PF00890.19 KEY66620.1 - 0.055 12.2 0.2 8.3 5.1 0.1 2.7 3 0 0 3 3 3 0 FAD binding domain Nop53 PF07767.6 KEY66621.1 - 7.3e-100 334.6 30.9 8.8e-100 334.4 21.4 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Ras PF00071.17 KEY66622.1 - 7.6e-59 197.7 0.5 1.3e-58 196.9 0.3 1.3 1 0 0 1 1 1 1 Ras family Kei1 PF08552.6 KEY66622.1 - 4.5e-50 169.9 1.8 9.2e-50 168.9 1.2 1.5 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Miro PF08477.8 KEY66622.1 - 7.3e-21 74.8 0.1 1.4e-20 73.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEY66622.1 - 1e-17 63.8 0.3 1.6e-17 63.3 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEY66622.1 - 5.1e-07 29.3 0.1 1.6e-06 27.7 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KEY66622.1 - 1.7e-05 24.0 0.4 2.6e-05 23.4 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KEY66622.1 - 4.3e-05 23.4 0.1 8.1e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KEY66622.1 - 4.5e-05 22.7 0.1 8.1e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Glyco_tran_WbsX PF14307.1 KEY66622.1 - 0.067 12.3 0.1 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase WbsX DFP PF04127.10 KEY66622.1 - 0.093 12.3 0.3 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein NIR_SIR PF01077.17 KEY66623.1 - 2.1e-51 173.3 0.3 1.6e-46 157.5 0.1 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 KEY66623.1 - 1.6e-31 107.7 0.0 1.1e-16 60.2 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 KEY66623.1 - 1e-28 100.1 0.0 2.4e-28 98.9 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 KEY66623.1 - 3.1e-08 33.4 0.1 1.5e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Chitin_synth_1 PF01644.12 KEY66624.1 - 1.9e-83 278.1 0.0 3e-83 277.5 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KEY66624.1 - 1.2e-32 111.4 0.1 2.5e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KEY66624.1 - 5.2e-26 91.1 2.6 9.2e-21 73.8 0.0 2.3 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KEY66624.1 - 1.9e-08 34.2 6.4 1e-07 31.9 4.5 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KEY66624.1 - 3.3e-06 27.0 0.0 5.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_hydro_32N PF00251.15 KEY66625.1 - 3.3e-77 259.8 3.1 4.3e-77 259.4 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KEY66625.1 - 5e-05 23.5 0.0 0.00012 22.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal PBC PF03792.8 KEY66626.1 - 0.08 12.6 0.7 0.18 11.4 0.4 1.6 2 0 0 2 2 2 0 PBC domain Sugar_tr PF00083.19 KEY66627.1 - 1.5e-89 300.6 29.9 1.8e-89 300.3 20.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY66627.1 - 4.2e-22 78.3 39.7 2.6e-18 65.8 14.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NAD_binding_5 PF07994.7 KEY66627.1 - 0.023 14.1 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Cupin_1 PF00190.17 KEY66628.1 - 7.4e-12 44.9 0.2 1.9e-11 43.5 0.1 1.7 1 1 1 2 2 2 1 Cupin Cupin_2 PF07883.6 KEY66628.1 - 0.035 13.6 0.0 0.7 9.4 0.0 2.3 2 0 0 2 2 2 0 Cupin domain MASE1 PF05231.9 KEY66628.1 - 0.13 11.2 0.9 0.27 10.2 0.6 1.6 1 1 0 1 1 1 0 MASE1 Peptidase_M50B PF13398.1 KEY66629.1 - 1.2e-55 188.0 19.4 1.5e-55 187.7 13.5 1.0 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.17 KEY66629.1 - 0.018 14.0 5.0 0.074 12.0 3.4 2.4 1 1 0 1 1 1 0 Peptidase family M50 Peptidase_M41 PF01434.13 KEY66629.1 - 0.022 14.2 0.1 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M41 Peptidase_M36 PF02128.10 KEY66629.1 - 0.17 10.6 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungalysin metallopeptidase (M36) Patched PF02460.13 KEY66629.1 - 2.4 5.9 5.5 3.8 5.3 3.8 1.2 1 0 0 1 1 1 0 Patched family Abhydrolase_6 PF12697.2 KEY66630.1 - 6.5e-25 88.3 0.6 9e-25 87.8 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY66630.1 - 3.5e-11 43.0 0.8 2.9e-10 40.1 0.4 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY66630.1 - 6.9e-11 42.0 0.1 1.5e-10 41.0 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KEY66630.1 - 0.00028 20.6 0.0 0.00056 19.7 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase BTB PF00651.26 KEY66631.1 - 2.8e-08 33.7 0.0 8.8e-08 32.1 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Fip1 PF05182.8 KEY66632.1 - 1.2e-20 72.5 1.4 2.3e-20 71.5 1.0 1.4 1 0 0 1 1 1 1 Fip1 motif Nucleoporin_FG PF13634.1 KEY66633.1 - 2.5e-33 114.6 132.8 2.1e-12 47.3 25.9 5.0 2 1 3 5 5 5 3 Nucleoporin FG repeat region DUF4455 PF14643.1 KEY66633.1 - 0.0012 17.5 0.3 0.59 8.7 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4455) Med15 PF09606.5 KEY66633.1 - 0.0085 14.3 66.7 0.012 13.8 46.2 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1451 PF07295.6 KEY66633.1 - 0.032 14.0 0.1 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) RNA_pol_3_Rpc31 PF11705.3 KEY66634.1 - 3.5e-37 128.5 0.9 4.8e-37 128.1 0.6 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.9 KEY66634.1 - 0.62 8.0 6.4 0.86 7.5 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Sec7 PF01369.15 KEY66636.1 - 5e-64 215.4 0.9 5e-64 215.4 0.6 2.9 3 1 1 4 4 4 1 Sec7 domain Sec7_N PF12783.2 KEY66636.1 - 1.9e-51 173.8 3.3 1.9e-51 173.8 2.3 3.3 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KEY66636.1 - 1.9e-33 113.7 0.4 2.8e-31 106.8 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) 2-oxoacid_dh PF00198.18 KEY66637.1 - 5.4e-77 258.1 0.1 7e-77 257.7 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KEY66637.1 - 2.3e-19 68.7 1.0 4.8e-19 67.7 0.7 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KEY66637.1 - 2.2e-13 49.5 0.8 5.3e-13 48.3 0.6 1.7 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.3 KEY66637.1 - 0.0026 18.0 1.4 0.011 16.0 0.1 2.3 1 1 0 2 2 2 1 Protein of unknown function (DUF3614) HlyD_3 PF13437.1 KEY66637.1 - 0.052 13.8 1.2 11 6.4 0.0 3.5 2 1 1 3 3 3 0 HlyD family secretion protein Ribosomal_60s PF00428.14 KEY66637.1 - 1.5 9.2 10.4 1.8 9.0 4.9 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Fungal_trans_2 PF11951.3 KEY66638.1 - 1.7e-50 171.7 1.4 2.1e-50 171.4 1.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY66638.1 - 0.00026 20.8 1.6 0.00042 20.1 1.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RseA_C PF03873.8 KEY66638.1 - 0.056 13.3 0.3 0.16 11.9 0.2 1.8 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain Rib_5-P_isom_A PF06026.9 KEY66640.1 - 4.4e-39 133.5 0.0 3.6e-38 130.5 0.0 2.0 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DUF1308 PF07000.6 KEY66641.1 - 2.4e-30 105.4 0.0 4.6e-30 104.4 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) Glyco_hydro_43 PF04616.9 KEY66642.1 - 5.7e-67 225.8 1.2 7.1e-67 225.4 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF3433 PF11915.3 KEY66643.1 - 3.9e-31 107.0 11.2 5e-19 68.2 1.0 3.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) RNase_P_p30 PF01876.11 KEY66643.1 - 0.13 11.4 0.2 0.28 10.4 0.1 1.4 1 0 0 1 1 1 0 RNase P subunit p30 Ribosomal_60s PF00428.14 KEY66644.1 - 0.009 16.3 2.1 0.016 15.6 1.4 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein AAA PF00004.24 KEY66645.1 - 3.8e-15 56.2 0.0 7.9e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEY66645.1 - 4.1e-05 23.2 0.0 0.0001 22.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KEY66645.1 - 0.0024 18.0 1.5 0.059 13.5 1.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEY66645.1 - 0.0038 16.9 0.0 0.015 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEY66645.1 - 0.012 15.6 0.3 0.051 13.5 0.2 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 KEY66645.1 - 0.013 16.3 0.2 0.05 14.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KEY66645.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KEY66645.1 - 0.14 11.3 0.0 0.34 10.0 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF4661 PF15576.1 KEY66645.1 - 0.61 9.6 19.0 1.2 8.7 13.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) PKD_channel PF08016.7 KEY66646.1 - 3.1e-05 22.6 18.6 0.0015 17.0 12.1 2.4 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 KEY66646.1 - 0.00065 18.9 23.4 0.046 12.9 16.2 2.6 1 1 0 1 1 1 1 Ion transport protein Macro PF01661.16 KEY66647.1 - 1.1e-41 141.4 0.0 1.5e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Macro domain tRNA-synt_1c PF00749.16 KEY66648.1 - 1.7e-97 325.8 0.0 2.8e-97 325.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KEY66648.1 - 2.7e-32 111.8 0.0 1.1e-31 109.8 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain ABC_tran PF00005.22 KEY66651.1 - 2.4e-47 160.6 0.2 5.9e-24 84.9 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KEY66651.1 - 3.9e-18 66.4 0.0 0.00071 19.6 0.0 4.4 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 KEY66651.1 - 4.6e-17 61.9 0.0 6.9e-06 25.4 0.0 3.6 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KEY66651.1 - 7.4e-10 38.2 0.0 0.0013 18.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KEY66651.1 - 1.5e-09 38.4 5.5 0.00011 22.6 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_17 PF13207.1 KEY66651.1 - 8.1e-09 36.3 0.1 0.00096 19.9 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 KEY66651.1 - 1.8e-08 34.5 0.0 0.00029 20.9 0.0 3.6 4 0 0 4 4 2 2 AAA domain DUF258 PF03193.11 KEY66651.1 - 5.3e-08 32.2 0.0 0.0005 19.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KEY66651.1 - 7.9e-07 29.0 0.0 0.011 15.6 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 KEY66651.1 - 1.1e-06 28.3 0.1 0.25 10.7 0.0 3.7 4 0 0 4 4 4 2 AAA-like domain AAA_33 PF13671.1 KEY66651.1 - 1.2e-06 28.4 0.1 0.054 13.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.1 KEY66651.1 - 2.8e-06 27.3 0.1 0.04 13.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KEY66651.1 - 3.2e-06 27.3 0.0 0.52 10.5 0.0 4.2 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 KEY66651.1 - 4.1e-06 27.2 0.1 0.018 15.5 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 KEY66651.1 - 4.4e-06 26.6 0.0 0.0011 18.7 0.0 2.7 2 0 0 2 2 2 1 Dynamin family MobB PF03205.9 KEY66651.1 - 7.1e-06 25.7 0.0 0.1 12.3 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 KEY66651.1 - 1.1e-05 25.2 0.0 0.04 13.8 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 KEY66651.1 - 1.9e-05 24.8 0.1 0.23 11.6 0.0 3.2 3 0 0 3 3 2 2 RNA helicase AAA_16 PF13191.1 KEY66651.1 - 2e-05 24.6 1.4 0.86 9.5 0.0 4.6 5 0 0 5 5 4 1 AAA ATPase domain ArgK PF03308.11 KEY66651.1 - 2.1e-05 23.4 0.1 0.21 10.3 0.0 2.5 2 0 0 2 2 2 2 ArgK protein AAA_18 PF13238.1 KEY66651.1 - 3.5e-05 24.0 2.3 0.27 11.5 0.0 4.0 4 0 0 4 4 3 2 AAA domain NACHT PF05729.7 KEY66651.1 - 8.7e-05 22.2 0.0 0.097 12.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.1 KEY66651.1 - 0.00017 20.7 11.1 0.19 10.7 0.0 5.2 4 2 1 6 6 6 1 AAA ATPase domain PduV-EutP PF10662.4 KEY66651.1 - 0.00018 21.0 0.0 0.29 10.6 0.0 3.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 KEY66651.1 - 0.00022 21.1 0.0 2.2 8.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 KEY66651.1 - 0.00026 20.7 0.2 1.4 8.5 0.0 3.2 3 0 0 3 3 2 2 Archaeal ATPase DUF87 PF01935.12 KEY66651.1 - 0.00047 20.0 1.0 0.33 10.7 0.0 3.8 5 0 0 5 5 3 1 Domain of unknown function DUF87 Septin PF00735.13 KEY66651.1 - 0.00083 18.4 0.3 0.19 10.7 0.0 3.1 3 0 0 3 3 3 1 Septin HEAT_2 PF13646.1 KEY66651.1 - 0.00088 19.5 4.9 0.54 10.5 4.1 3.2 1 1 2 3 3 3 2 HEAT repeats cobW PF02492.14 KEY66651.1 - 0.00099 18.6 0.2 1.9 7.8 0.0 3.2 4 0 0 4 4 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.1 KEY66651.1 - 0.0011 17.4 4.0 1.4 7.2 0.0 4.1 4 1 0 4 4 4 1 AAA domain AAA_25 PF13481.1 KEY66651.1 - 0.0012 18.2 0.0 0.99 8.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain ATP-synt_ab PF00006.20 KEY66651.1 - 0.0026 17.2 0.0 1.7 8.1 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain MutS_V PF00488.16 KEY66651.1 - 0.0033 16.8 0.1 0.75 9.1 0.0 2.5 2 0 0 2 2 2 1 MutS domain V AAA_30 PF13604.1 KEY66651.1 - 0.0046 16.5 0.0 6.1 6.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain Cnd1 PF12717.2 KEY66651.1 - 0.011 15.5 0.2 0.1 12.4 0.0 2.5 3 0 0 3 3 2 0 non-SMC mitotic condensation complex subunit 1 ATP_bind_1 PF03029.12 KEY66651.1 - 0.014 14.9 0.3 7.8 5.9 0.0 3.1 4 0 0 4 4 2 0 Conserved hypothetical ATP binding protein HEAT PF02985.17 KEY66651.1 - 0.014 15.4 0.4 27 5.1 0.1 4.1 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.1 KEY66651.1 - 0.021 15.3 5.1 14 6.3 0.0 5.5 4 1 2 6 6 4 0 HEAT-like repeat T2SE PF00437.15 KEY66651.1 - 0.025 13.4 0.2 2 7.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 KEY66651.1 - 0.03 13.8 0.3 4.3 6.7 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 KEY66651.1 - 0.04 13.6 0.0 13 5.4 0.0 2.9 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.17 KEY66651.1 - 0.041 12.7 0.1 0.52 9.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.10 KEY66651.1 - 0.058 12.0 0.0 4.5 5.8 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 KEY66651.1 - 0.062 13.0 0.0 3.6 7.3 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain Mg_chelatase PF01078.16 KEY66651.1 - 0.07 12.2 0.0 4.6 6.3 0.0 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI DAP3 PF10236.4 KEY66651.1 - 0.31 9.9 3.0 15 4.3 0.1 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 ADH_zinc_N PF00107.21 KEY66652.1 - 1.5e-16 60.0 0.0 2.5e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY66652.1 - 4.6e-07 30.7 0.0 9.6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AA_permease PF00324.16 KEY66654.1 - 8.8e-97 324.4 45.2 1.1e-96 324.1 31.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEY66654.1 - 9.8e-21 73.7 51.0 1.2e-20 73.4 35.3 1.0 1 0 0 1 1 1 1 Amino acid permease TPR_11 PF13414.1 KEY66655.1 - 5.3e-11 42.0 0.2 2.8e-08 33.3 0.1 4.5 4 1 1 5 5 5 3 TPR repeat TPR_2 PF07719.12 KEY66655.1 - 7.2e-09 34.8 2.2 0.39 10.7 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEY66655.1 - 1.9e-08 33.4 0.2 0.2 11.5 0.0 4.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEY66655.1 - 2.7e-08 33.0 0.9 0.051 13.1 0.5 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEY66655.1 - 4.9e-07 29.5 4.7 0.84 9.6 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEY66655.1 - 1.6e-06 28.5 4.6 7.6e-06 26.4 0.0 3.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEY66655.1 - 6.4e-06 26.4 0.1 0.23 11.8 0.0 3.4 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEY66655.1 - 0.0013 18.5 1.6 0.0062 16.3 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KEY66655.1 - 0.0037 17.3 3.6 0.97 9.6 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KEY66655.1 - 0.014 15.9 17.2 0.48 11.2 0.0 5.7 5 1 1 6 6 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEY66655.1 - 0.063 13.1 6.0 0.78 9.6 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat GYF PF02213.11 KEY66656.1 - 9e-20 70.0 0.1 2.2e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 GYF domain UPF0086 PF01868.11 KEY66657.1 - 2.6e-23 81.4 0.1 4.6e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Acyltransferase PF01553.16 KEY66658.1 - 4.5e-17 61.7 0.0 8.8e-17 60.7 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Pantoate_ligase PF02569.10 KEY66659.1 - 1.4e-81 273.3 0.0 2.6e-81 272.4 0.0 1.4 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase DUF3134 PF11332.3 KEY66660.1 - 0.015 15.4 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) WD40 PF00400.27 KEY66661.1 - 4.1e-19 67.6 10.3 0.0016 18.2 0.2 6.3 5 2 0 5 5 5 5 WD domain, G-beta repeat MFS_1 PF07690.11 KEY66662.1 - 1.2e-41 142.5 31.9 1.2e-41 142.5 22.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KEY66662.1 - 2.1e-09 36.1 3.8 3.4e-09 35.4 2.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KEY66662.1 - 5.4e-09 35.1 24.8 1.6e-08 33.5 17.2 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2178 PF09946.4 KEY66662.1 - 0.88 9.3 6.4 0.15 11.8 0.8 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) Zn_clus PF00172.13 KEY66664.1 - 1.8e-06 27.7 12.6 4.2e-06 26.5 8.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEY66664.1 - 0.058 11.9 0.7 0.13 10.8 0.1 1.8 2 0 0 2 2 2 0 Fungal specific transcription factor domain TPR_11 PF13414.1 KEY66665.1 - 3.1e-11 42.7 1.9 3.1e-11 42.7 1.3 2.1 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 KEY66665.1 - 0.00023 20.8 4.8 0.22 11.5 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEY66665.1 - 0.0003 20.6 1.7 0.0022 17.8 1.4 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEY66665.1 - 0.00035 20.0 2.8 0.14 11.7 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEY66665.1 - 0.0063 16.8 0.6 0.023 15.0 0.4 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEY66665.1 - 0.053 14.1 13.4 2.2 9.1 0.0 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEY66665.1 - 0.08 12.7 1.4 2.6 8.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEY66665.1 - 0.17 11.8 1.5 9.1 6.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEY66665.1 - 3.8 8.3 15.2 0.12 13.0 1.7 3.1 2 2 0 2 2 2 0 Tetratricopeptide repeat HAD_2 PF13419.1 KEY66666.1 - 4e-15 56.4 0.0 5.6e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEY66666.1 - 1.1e-06 29.2 0.0 7.1e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEY66666.1 - 5.1e-05 22.9 0.0 8.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NT5C PF06941.7 KEY66666.1 - 0.069 12.6 0.0 0.16 11.4 0.0 1.5 1 1 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Pyr_redox_2 PF07992.9 KEY66667.1 - 2.6e-12 47.0 0.0 4.8e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY66667.1 - 2.6e-05 24.3 0.2 0.13 12.3 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEY66667.1 - 0.00012 21.1 0.5 0.0021 17.0 0.1 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KEY66667.1 - 0.0002 21.1 0.4 0.42 10.3 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.17 KEY66667.1 - 0.00035 19.5 0.0 0.64 8.8 0.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A K_oxygenase PF13434.1 KEY66667.1 - 0.0012 17.8 0.2 0.0088 15.0 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KEY66667.1 - 0.0013 17.2 0.0 0.0082 14.6 0.0 2.1 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.1 KEY66667.1 - 0.0027 17.6 0.1 0.0073 16.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEY66667.1 - 0.0096 14.8 0.1 0.051 12.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KEY66667.1 - 0.026 13.6 0.1 0.057 12.5 0.1 1.5 1 0 0 1 1 1 0 Thi4 family FYVE PF01363.16 KEY66668.1 - 0.048 13.5 2.1 0.074 12.9 1.5 1.4 1 1 0 1 1 1 0 FYVE zinc finger RR_TM4-6 PF06459.7 KEY66668.1 - 4.3 7.1 10.4 4.6 7.0 7.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FYDLN_acid PF09538.5 KEY66668.1 - 4.8 7.8 11.4 7.9 7.1 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) APH PF01636.18 KEY66670.1 - 0.21 11.2 1.3 0.28 10.8 0.1 1.8 3 0 0 3 3 3 0 Phosphotransferase enzyme family HET PF06985.6 KEY66671.1 - 5.1e-37 127.1 0.0 4.1e-29 101.5 0.0 3.6 2 1 1 3 3 3 3 Heterokaryon incompatibility protein (HET) Oxidored_FMN PF00724.15 KEY66673.1 - 4.3e-46 157.4 0.0 6.1e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 KEY66673.1 - 0.003 16.4 0.0 0.0065 15.3 0.0 1.5 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Dynamin_N PF00350.18 KEY66675.1 - 1.3e-13 51.1 0.0 4.2e-13 49.4 0.0 1.9 1 0 0 1 1 1 1 Dynamin family DUF258 PF03193.11 KEY66675.1 - 8.1e-08 31.6 0.0 3.8e-06 26.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KEY66675.1 - 4.5e-07 29.8 0.0 0.00088 19.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KEY66675.1 - 0.00036 20.5 0.1 0.0016 18.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 KEY66675.1 - 0.0004 20.7 0.0 0.0021 18.3 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_10 PF12846.2 KEY66675.1 - 0.016 14.6 0.0 0.93 8.8 0.0 2.8 2 1 0 2 2 2 0 AAA-like domain FeoB_N PF02421.13 KEY66675.1 - 0.036 13.3 0.0 4.3 6.5 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Miro PF08477.8 KEY66675.1 - 0.055 13.9 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AIG1 PF04548.11 KEY66675.1 - 0.059 12.4 0.0 0.49 9.4 0.0 2.3 2 0 0 2 2 2 0 AIG1 family AAA_29 PF13555.1 KEY66675.1 - 0.11 12.0 0.1 0.25 10.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain BLVR PF06375.6 KEY66676.1 - 5.7 6.7 8.3 8.3 6.2 5.8 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Fungal_trans PF04082.13 KEY66677.1 - 4.9e-10 38.7 0.0 8.3e-10 37.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY66677.1 - 6.6e-06 25.9 7.2 1.3e-05 24.9 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_61 PF03443.9 KEY66679.1 - 3.2e-54 184.0 0.0 4.1e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ank_2 PF12796.2 KEY66680.1 - 2.6e-92 303.3 4.9 1.3e-16 60.6 0.1 9.5 3 2 5 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 KEY66680.1 - 1.3e-69 226.7 19.5 6.8e-07 28.7 0.1 16.4 16 0 0 16 16 16 11 Ankyrin repeat Ank_4 PF13637.1 KEY66680.1 - 2.1e-58 193.6 10.9 1.9e-07 31.4 0.1 11.6 6 4 4 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY66680.1 - 5.1e-57 184.1 11.7 1.1e-06 28.2 0.0 18.8 19 0 0 19 19 19 9 Ankyrin repeat Ank_5 PF13857.1 KEY66680.1 - 5e-51 169.5 20.9 5.2e-07 29.6 0.3 13.6 5 4 9 14 14 14 11 Ankyrin repeats (many copies) NACHT PF05729.7 KEY66680.1 - 5.3e-07 29.4 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.9 KEY66680.1 - 1.2e-05 24.6 0.1 3.7e-05 23.1 0.1 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) AAA_16 PF13191.1 KEY66680.1 - 3.4e-05 23.8 0.6 0.00013 22.0 0.0 2.3 2 0 0 2 2 1 1 AAA ATPase domain PGAP1 PF07819.8 KEY66680.1 - 0.0014 18.2 0.0 0.0046 16.5 0.0 1.8 1 1 0 1 1 1 1 PGAP1-like protein AAA_22 PF13401.1 KEY66680.1 - 0.0025 17.9 0.0 0.0093 16.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain Abhydrolase_6 PF12697.2 KEY66680.1 - 0.0026 17.6 0.0 0.013 15.3 0.0 2.3 2 0 0 2 2 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KEY66680.1 - 0.0042 16.8 0.0 0.0085 15.8 0.0 1.4 1 0 0 1 1 1 1 Cutinase Arch_ATPase PF01637.13 KEY66680.1 - 0.0059 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase KAP_NTPase PF07693.9 KEY66680.1 - 0.016 14.2 4.2 0.74 8.7 0.1 3.2 2 1 1 3 3 3 0 KAP family P-loop domain Docking PF08990.6 KEY66680.1 - 0.018 14.2 0.3 0.04 13.1 0.2 1.7 1 0 0 1 1 1 0 Erythronolide synthase docking Abhydrolase_5 PF12695.2 KEY66680.1 - 0.032 13.9 0.0 0.083 12.6 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family ZZ PF00569.12 KEY66680.1 - 0.043 13.3 9.3 0.069 12.6 5.5 1.9 2 0 0 2 2 2 0 Zinc finger, ZZ type ABC_tran PF00005.22 KEY66680.1 - 0.083 13.1 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter LCAT PF02450.10 KEY66680.1 - 0.16 10.9 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase RNA_helicase PF00910.17 KEY66680.1 - 0.17 12.0 0.0 0.48 10.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase SDA1 PF05285.7 KEY66680.1 - 8 5.6 17.6 0.79 8.9 0.8 2.2 2 0 0 2 2 2 0 SDA1 NAD_binding_2 PF03446.10 KEY66681.1 - 3.7e-24 85.4 0.4 5.8e-24 84.7 0.3 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KEY66681.1 - 1.1e-09 38.3 0.0 2.4e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KEY66681.1 - 9.6e-07 29.1 0.0 2.6e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.4 KEY66681.1 - 0.0051 16.5 1.0 0.035 13.8 0.2 2.2 1 1 1 2 2 2 1 Rossmann-like domain 2CSK_N PF08521.5 KEY66681.1 - 0.031 13.8 0.4 0.055 12.9 0.3 1.4 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal DUF4139 PF13598.1 KEY66682.1 - 1.7e-55 188.5 16.1 1.4e-42 146.1 0.0 4.0 2 1 0 3 3 3 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 KEY66682.1 - 2e-12 47.4 13.0 1.3e-11 44.8 0.2 3.9 2 1 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) DUF4631 PF15450.1 KEY66684.1 - 0.027 12.7 2.5 0.12 10.6 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4631) Methyltransf_10 PF05971.7 KEY66685.1 - 2.7e-63 213.8 0.0 3.6e-63 213.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 KEY66685.1 - 9.3e-06 25.6 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY66685.1 - 0.00011 22.7 0.0 0.00032 21.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KEY66685.1 - 0.00066 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KEY66685.1 - 0.02 13.9 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 KEY66685.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF218 PF02698.12 KEY66686.1 - 1.3e-32 112.4 0.0 1.7e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain adh_short_C2 PF13561.1 KEY66687.1 - 6.5e-29 101.3 0.0 8.5e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEY66687.1 - 4.8e-26 91.6 3.3 6.5e-26 91.2 2.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY66687.1 - 7.9e-15 54.9 2.7 1.2e-14 54.3 1.9 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY66687.1 - 5.4e-07 29.2 0.0 7.5e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEY66687.1 - 8.9e-06 24.5 0.4 1.2e-05 24.1 0.3 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KEY66687.1 - 0.00035 19.5 0.0 0.0005 19.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Pyr_redox_3 PF13738.1 KEY66687.1 - 0.023 14.7 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 KEY66687.1 - 0.029 14.3 2.0 0.042 13.8 0.7 1.9 2 1 0 2 2 1 0 NADH(P)-binding F420_oxidored PF03807.12 KEY66687.1 - 0.03 14.7 0.7 0.098 13.0 0.0 2.1 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 KEY66687.1 - 0.044 13.6 0.2 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 ThiF family NmrA PF05368.8 KEY66687.1 - 0.062 12.5 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family 2-Hacid_dh_C PF02826.14 KEY66687.1 - 0.08 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 KEY66687.1 - 0.1 12.4 0.1 0.24 11.2 0.0 1.6 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain GST_N_3 PF13417.1 KEY66688.1 - 1.2e-26 92.7 0.1 3e-26 91.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEY66688.1 - 1e-17 63.8 0.1 8.4e-17 60.9 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEY66688.1 - 7e-07 29.0 0.3 1.2e-06 28.3 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KEY66688.1 - 3.8e-06 26.9 0.0 6.5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KEY66688.1 - 4.6e-05 23.3 0.0 9.7e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEY66688.1 - 0.00025 21.4 0.1 0.0023 18.3 0.0 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain XAP5 PF04921.9 KEY66689.1 - 5e-79 265.2 0.0 6.4e-79 264.9 0.0 1.1 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF2165 PF09933.4 KEY66690.1 - 1.3 8.7 11.3 0.44 10.2 5.1 1.9 1 1 1 2 2 2 0 Predicted small integral membrane protein (DUF2165) AAA_10 PF12846.2 KEY66691.1 - 1.1e-06 28.3 0.0 0.042 13.2 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain Zeta_toxin PF06414.7 KEY66691.1 - 0.049 12.7 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Zot PF05707.7 KEY66691.1 - 0.075 12.4 0.0 0.75 9.2 0.0 2.1 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) FtsK_SpoIIIE PF01580.13 KEY66691.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Glyco_hydro_3 PF00933.16 KEY66692.1 - 2.4e-81 273.0 0.0 3.4e-81 272.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY66692.1 - 2.1e-44 151.7 0.5 5.5e-43 147.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEY66692.1 - 2.7e-22 78.4 0.0 5.3e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_2_N PF02837.13 KEY66693.1 - 1.7e-25 89.4 0.0 7.3e-25 87.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KEY66693.1 - 5.6e-11 41.8 0.0 1.1e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KEY66693.1 - 4e-07 30.4 0.0 1.1e-06 29.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BTB PF00651.26 KEY66697.1 - 2.8e-06 27.2 0.0 1.1e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain DUF4090 PF13319.1 KEY66697.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4090) Fungal_trans_2 PF11951.3 KEY66699.1 - 3.7e-38 131.1 5.1 4.6e-38 130.8 3.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain PhyH PF05721.8 KEY66700.1 - 1.6e-19 70.8 0.0 2e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KEY66700.1 - 0.072 11.5 0.0 0.11 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) AA_permease PF00324.16 KEY66701.1 - 1.2e-106 356.9 41.5 1.4e-106 356.7 28.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEY66701.1 - 3.2e-32 111.6 46.7 4e-32 111.2 32.4 1.1 1 0 0 1 1 1 1 Amino acid permease Aminotran_1_2 PF00155.16 KEY66702.1 - 2.3e-26 92.6 0.0 3.3e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KEY66702.1 - 0.058 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Lipase_GDSL_2 PF13472.1 KEY66703.1 - 8.4e-14 52.0 0.1 1.5e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KEY66703.1 - 1.7e-11 44.3 0.1 5e-11 42.8 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CBM_1 PF00734.13 KEY66703.1 - 4.8e-09 35.7 14.2 1.1e-08 34.5 9.9 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KEY66703.1 - 0.19 11.7 8.0 0.42 10.6 5.5 1.6 1 0 0 1 1 1 0 Toxin 7 Zn_clus PF00172.13 KEY66704.1 - 2.8e-06 27.1 5.6 2.8e-06 27.1 3.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KEY66705.1 - 5.6e-21 75.1 0.3 7.6e-21 74.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY66705.1 - 1.9e-10 40.9 0.0 5.7e-10 39.3 0.0 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY66705.1 - 2.5e-10 40.3 0.1 3.3e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KEY66705.1 - 5.7e-08 31.9 0.0 7.3e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KEY66705.1 - 1.3e-06 28.0 0.0 2.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KEY66705.1 - 0.0054 16.4 0.4 0.012 15.3 0.3 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HAD_2 PF13419.1 KEY66707.1 - 1.1e-06 29.0 0.0 3.2e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEY66707.1 - 4.2e-06 26.3 0.0 8.9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KEY66707.1 - 0.0058 17.0 0.0 0.0072 16.7 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Aldo_ket_red PF00248.16 KEY66708.1 - 2.4e-70 236.5 0.0 3e-70 236.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PigN PF04987.9 KEY66708.1 - 0.19 10.3 0.0 0.25 9.9 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) GTP_EFTU PF00009.22 KEY66709.1 - 7.8e-48 162.4 0.0 1.1e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 KEY66709.1 - 1.3e-33 115.1 2.4 2.3e-33 114.2 1.7 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 KEY66709.1 - 1.3e-11 44.1 0.0 2.7e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KEY66709.1 - 5.2e-06 26.4 0.2 1.4e-05 25.1 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEY66709.1 - 1.7e-05 24.7 0.1 0.00013 21.8 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.17 KEY66709.1 - 2.8e-05 23.5 0.0 0.0038 16.6 0.0 2.3 2 0 0 2 2 2 1 Ras family EFG_II PF14492.1 KEY66709.1 - 0.00065 19.5 0.0 0.002 17.9 0.0 1.9 1 1 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 KEY66709.1 - 0.013 14.7 0.0 0.048 12.8 0.0 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 KEY66709.1 - 0.041 14.3 0.0 0.13 12.7 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein Glyco_hydro_61 PF03443.9 KEY66710.1 - 4.9e-34 118.0 0.0 5.6e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF159 PF02586.9 KEY66711.1 - 2.8e-54 183.8 0.1 5.3e-54 182.9 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised ACR, COG2135 DDHD PF02862.12 KEY66712.1 - 3.9e-68 229.6 5.3 1.2e-67 228.0 0.0 3.1 3 1 0 3 3 3 1 DDHD domain Abhydrolase_5 PF12695.2 KEY66712.1 - 0.067 12.9 0.0 0.72 9.6 0.0 2.2 1 1 0 2 2 2 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KEY66712.1 - 0.11 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2305 PF10230.4 KEY66712.1 - 0.16 11.3 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF3530 PF12048.3 KEY66712.1 - 0.89 8.4 8.0 0.031 13.2 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) CH PF00307.26 KEY66714.1 - 6.6e-62 206.2 0.0 2.5e-18 66.0 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 KEY66714.1 - 1.6e-05 24.9 0.5 0.00035 20.6 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KEY66714.1 - 0.037 13.3 0.3 12 5.5 0.0 3.5 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.1 KEY66714.1 - 0.26 11.2 1.5 3.6 7.7 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain RRM_1 PF00076.17 KEY66715.1 - 3.5e-08 32.9 0.0 3.9e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY66715.1 - 2.6e-06 27.1 0.0 4.4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY66715.1 - 2.8e-05 23.9 0.0 0.01 15.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEY66715.1 - 0.16 11.8 0.0 0.46 10.2 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Mito_carr PF00153.22 KEY66716.1 - 3.1e-78 257.5 1.2 2.1e-25 88.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L18e PF00828.14 KEY66717.1 - 5.8e-24 84.9 0.2 5.8e-24 84.9 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 FtsJ PF01728.14 KEY66718.1 - 8.5e-46 156.2 0.0 1e-44 152.7 0.0 2.2 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 KEY66718.1 - 0.0001 22.0 0.0 0.00058 19.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY66718.1 - 0.0045 17.5 0.0 0.025 15.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY66718.1 - 0.051 13.1 0.0 0.55 9.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain CCDC144C PF14915.1 KEY66719.1 - 0.0039 16.1 40.0 0.0039 16.1 27.8 2.2 1 1 0 1 1 1 1 CCDC144C protein coiled-coil region Filament PF00038.16 KEY66719.1 - 0.052 13.0 44.7 0.025 14.0 9.7 3.6 1 1 2 3 3 3 0 Intermediate filament protein GAS PF13851.1 KEY66719.1 - 0.18 10.9 46.6 0.081 12.1 10.2 3.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.7 KEY66719.1 - 0.24 11.1 11.4 0.65 9.8 1.7 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.3 KEY66719.1 - 0.47 7.7 42.3 0.78 6.9 29.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IncA PF04156.9 KEY66719.1 - 1.1 8.8 54.7 0.87 9.1 11.0 3.3 1 1 0 2 2 2 0 IncA protein Reo_sigmaC PF04582.7 KEY66719.1 - 6 5.9 14.9 3.2 6.8 3.1 2.7 1 1 0 2 2 2 0 Reovirus sigma C capsid protein OST3_OST6 PF04756.8 KEY66720.1 - 1.1e-20 73.7 0.6 1.6e-20 73.2 0.4 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 KEY66720.1 - 0.17 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin VKOR PF07884.9 KEY66720.1 - 1 9.1 7.3 0.093 12.5 1.4 1.8 2 0 0 2 2 2 0 Vitamin K epoxide reductase family Glyco_hydro_6 PF01341.12 KEY66721.1 - 1.5e-92 310.2 0.3 1.8e-92 309.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 WD40 PF00400.27 KEY66722.1 - 1.8e-61 201.9 26.4 1.2e-11 43.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KEY66722.1 - 5.3e-06 24.8 7.0 0.25 9.4 0.1 4.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KEY66722.1 - 0.019 13.2 0.0 4 5.6 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Glyco_hydro_15 PF00723.16 KEY66723.1 - 2.6e-91 306.4 0.1 3.2e-91 306.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 KEY66723.1 - 4e-29 100.0 0.0 7.8e-29 99.1 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain DHH PF01368.15 KEY66724.1 - 6.3e-07 29.1 0.1 8.9e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 DHH family Fungal_trans PF04082.13 KEY66726.1 - 1.2e-25 89.9 1.1 1.8e-25 89.3 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MR_MLE_C PF13378.1 KEY66727.1 - 2.1e-19 69.5 0.0 3.9e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KEY66727.1 - 1.9e-12 47.5 0.0 4.3e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KEY66727.1 - 1e-09 38.4 0.0 1.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyco_hydro_42 PF02449.10 KEY66727.1 - 0.07 12.2 0.0 0.16 11.0 0.0 1.5 2 0 0 2 2 2 0 Beta-galactosidase adh_short PF00106.20 KEY66728.1 - 2.8e-28 98.9 1.9 3.7e-28 98.5 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY66728.1 - 2.9e-22 79.6 0.0 3.5e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY66728.1 - 2.3e-12 46.9 1.1 3.6e-12 46.3 0.8 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY66728.1 - 0.0099 15.3 0.3 0.015 14.7 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KEY66728.1 - 0.066 12.0 0.1 0.11 11.3 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Hydrolase_6 PF13344.1 KEY66729.1 - 7.6e-22 77.1 0.0 1.4e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEY66729.1 - 7.4e-12 44.8 0.0 4.7e-11 42.2 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like Mitochondr_Som1 PF11093.3 KEY66731.1 - 0.068 12.9 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial export protein Som1 Ribosomal_L22 PF00237.14 KEY66733.1 - 2.6e-11 43.4 0.0 3.3e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e CFEM PF05730.6 KEY66734.1 - 2.1e-08 33.8 9.6 3.5e-08 33.1 6.7 1.3 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.5 KEY66734.1 - 3.4e-06 26.2 1.7 6.8e-06 25.2 1.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 KEY66734.1 - 0.00052 19.5 0.0 0.00085 18.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Podoplanin PF05808.6 KEY66734.1 - 0.035 13.6 4.5 0.12 11.9 3.2 1.9 1 1 0 1 1 1 0 Podoplanin CDC27 PF09507.5 KEY66734.1 - 0.98 8.5 14.4 1.3 8.1 10.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RRM_1 PF00076.17 KEY66735.1 - 1.8e-49 165.2 0.1 1.2e-16 60.1 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY66735.1 - 1.4e-41 140.3 0.0 9.7e-13 47.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY66735.1 - 4.6e-20 71.2 0.0 1.7e-07 30.9 0.0 4.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEY66735.1 - 5e-08 32.5 0.0 0.02 14.6 0.0 3.6 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 KEY66735.1 - 4.6e-05 23.1 0.0 0.0014 18.2 0.0 2.9 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KEY66735.1 - 7e-05 22.6 0.1 0.091 12.6 0.0 3.1 2 0 0 2 2 2 2 RNA binding motif Lsm_interact PF05391.6 KEY66735.1 - 0.02 14.3 0.1 0.072 12.5 0.1 2.1 1 0 0 1 1 1 0 Lsm interaction motif HA2 PF04408.18 KEY66736.1 - 3e-19 68.9 0.1 7.9e-19 67.5 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KEY66736.1 - 1.4e-12 47.2 0.0 3.8e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEY66736.1 - 2.2e-10 40.3 0.0 5.3e-10 39.0 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEY66736.1 - 1.7e-08 34.6 0.6 1e-07 32.1 0.0 2.5 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.17 KEY66736.1 - 0.013 14.3 0.0 0.03 13.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.1 KEY66736.1 - 0.027 13.9 0.0 0.06 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KEY66736.1 - 0.033 13.6 0.0 0.1 12.0 0.0 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.22 KEY66736.1 - 0.04 14.2 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 ABC transporter KaiC PF06745.8 KEY66736.1 - 0.072 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 KEY66736.1 - 0.1 12.5 0.0 1.7 8.5 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KEY66736.1 - 3.7 7.8 0.0 3.7 7.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain DUF3554 PF12074.3 KEY66737.1 - 3e-71 240.6 1.8 3e-71 240.6 1.3 4.7 5 0 0 5 5 5 1 Domain of unknown function (DUF3554) Ribosomal_L19e PF01280.15 KEY66737.1 - 2.7e-59 199.1 9.6 7.2e-59 197.7 6.6 1.8 1 0 0 1 1 1 1 Ribosomal protein L19e HEAT PF02985.17 KEY66737.1 - 8.3e-40 131.3 34.7 0.012 15.5 0.1 21.5 25 0 0 25 25 23 11 HEAT repeat HEAT_2 PF13646.1 KEY66737.1 - 2.6e-38 130.1 62.7 2.1e-10 40.7 0.0 17.0 11 3 6 17 17 17 10 HEAT repeats HEAT_EZ PF13513.1 KEY66737.1 - 8.7e-33 111.9 62.6 8.2e-07 29.3 0.0 24.0 18 3 9 27 27 27 9 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KEY66737.1 - 8.5e-16 58.1 0.0 0.14 12.5 0.0 9.0 8 1 1 9 9 9 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KEY66737.1 - 2.1e-12 46.9 0.0 0.002 17.5 0.0 6.3 5 1 3 8 8 8 4 CLASP N terminal ParcG PF10274.4 KEY66737.1 - 2.6e-11 43.7 2.4 3.4e-05 23.8 0.0 6.2 6 1 1 7 7 7 2 Parkin co-regulated protein Cnd1 PF12717.2 KEY66737.1 - 5.4e-10 39.3 0.1 0.54 10.0 0.0 8.4 8 1 3 11 11 11 2 non-SMC mitotic condensation complex subunit 1 UME PF08064.8 KEY66737.1 - 3.4e-06 26.9 1.0 9.1 6.2 0.0 7.2 6 2 3 9 9 9 1 UME (NUC010) domain Ipi1_N PF12333.3 KEY66737.1 - 3e-05 23.8 2.1 0.012 15.5 0.0 6.2 8 0 0 8 8 8 1 Rix1 complex component involved in 60S ribosome maturation AAA_10 PF12846.2 KEY66737.1 - 0.2 11.0 4.4 4 6.7 0.0 4.4 4 1 0 5 5 5 0 AAA-like domain SHMT PF00464.14 KEY66738.1 - 7.5e-197 653.5 0.0 8.8e-197 653.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Isochorismatase PF00857.15 KEY66739.1 - 3.9e-27 95.2 1.0 8.2e-27 94.2 0.0 2.1 2 1 0 2 2 2 1 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.1 KEY66739.1 - 2.4e-25 89.4 0.0 4.7e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GST_C_3 PF14497.1 KEY66739.1 - 0.00011 22.6 0.0 0.00026 21.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KEY66739.1 - 0.00056 19.7 0.2 0.0014 18.5 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TAF8_C PF10406.4 KEY66740.1 - 4.6e-16 58.5 1.1 8e-16 57.8 0.1 2.0 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 KEY66740.1 - 9.3e-11 41.3 0.0 1.6e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Herpes_alk_exo PF01771.12 KEY66740.1 - 0.066 11.6 0.0 0.087 11.2 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus alkaline exonuclease Histone PF00125.19 KEY66740.1 - 0.066 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 GST_C_2 PF13410.1 KEY66741.1 - 8.2e-10 38.4 0.3 1.6e-09 37.4 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KEY66741.1 - 2.2e-08 34.1 0.0 4.6e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KEY66741.1 - 1.8e-06 28.3 0.1 3.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KEY66741.1 - 1.4e-05 24.9 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KEY66741.1 - 1.8e-05 24.6 0.0 3.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain adh_short PF00106.20 KEY66743.1 - 7.3e-17 61.7 1.0 1.4e-16 60.8 0.5 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY66743.1 - 1.8e-08 34.2 0.6 2.8e-08 33.6 0.4 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY66743.1 - 8.2e-06 25.7 0.1 1.2e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEY66743.1 - 0.00012 21.5 0.0 0.00019 20.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KEY66743.1 - 0.0012 18.9 0.0 0.0026 17.8 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DDE_Tnp_Tn3 PF01526.12 KEY66743.1 - 0.0081 14.8 0.1 0.23 10.0 0.0 2.2 1 1 1 2 2 2 1 Tn3 transposase DDE domain Polysacc_synt_2 PF02719.10 KEY66743.1 - 0.046 12.6 0.0 0.074 11.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Alpha-amylase PF00128.19 KEY66744.1 - 1.6e-96 323.4 0.0 2.4e-96 322.8 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KEY66744.1 - 0.0033 16.3 0.0 0.005 15.7 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDPD PF03009.12 KEY66744.1 - 0.11 12.0 0.1 9.7 5.6 0.0 2.2 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Sugar_tr PF00083.19 KEY66745.1 - 5.5e-81 272.4 17.5 6.4e-81 272.2 12.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY66745.1 - 2.8e-20 72.3 26.4 7.8e-19 67.5 13.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEY66745.1 - 4.7e-06 25.2 24.2 0.00026 19.5 2.6 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein Fungal_trans PF04082.13 KEY66746.1 - 0.0064 15.3 0.7 0.036 12.9 0.5 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Pox_A9 PF04835.7 KEY66746.1 - 0.25 11.3 0.8 0.57 10.1 0.6 1.7 1 0 0 1 1 1 0 A9 protein conserved region Zn_clus PF00172.13 KEY66746.1 - 1.1 9.1 16.4 0.12 12.2 8.2 1.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C3HC4_2 PF13923.1 KEY66747.1 - 1.8e-08 34.2 6.9 3.1e-08 33.5 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEY66747.1 - 4.3e-08 32.8 4.2 7.3e-08 32.1 2.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KEY66747.1 - 4.4e-08 32.6 5.2 7.8e-08 31.8 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEY66747.1 - 1.1e-07 31.4 4.0 1.8e-07 30.7 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY66747.1 - 2.6e-06 27.0 4.3 4.5e-06 26.2 3.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KEY66747.1 - 6.1e-06 26.0 5.5 3.6e-05 23.5 4.0 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KEY66747.1 - 0.0026 17.4 2.5 0.0026 17.4 1.7 1.9 1 1 0 1 1 1 1 RING-type zinc-finger Drf_FH3 PF06367.11 KEY66747.1 - 0.029 13.7 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Diaphanous FH3 Domain ChW PF07538.6 KEY66747.1 - 0.036 13.5 0.0 0.093 12.2 0.0 1.7 1 0 0 1 1 1 0 Clostridial hydrophobic W zf-MIZ PF02891.15 KEY66747.1 - 0.048 13.1 4.3 0.12 11.9 3.0 1.7 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.2 KEY66747.1 - 0.12 12.5 2.0 0.28 11.3 1.4 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger TerY-C PF15616.1 KEY66747.1 - 0.95 9.4 3.7 2.8 7.8 2.6 1.7 1 1 0 1 1 1 0 TerY-C metal binding domain Glyco_hydro_114 PF03537.8 KEY66750.1 - 5.8e-24 83.6 0.2 9.3e-24 83.0 0.1 1.3 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 SPOC PF07744.8 KEY66751.1 - 3.2e-18 66.3 0.0 7.1e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.9 KEY66751.1 - 1.1e-16 60.8 1.1 1.1e-16 60.8 0.8 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 KEY66751.1 - 1.5e-08 34.1 9.5 2.7e-08 33.3 6.6 1.4 1 0 0 1 1 1 1 PHD-finger ECIST_Cterm PF14784.1 KEY66751.1 - 0.0085 16.0 0.7 0.031 14.2 0.5 1.9 1 0 0 1 1 1 1 C-terminal domain of the ECSIT protein Med7 PF05983.6 KEY66752.1 - 5.1e-51 172.6 0.1 6.1e-51 172.4 0.1 1.1 1 0 0 1 1 1 1 MED7 protein zf-met PF12874.2 KEY66753.1 - 0.0075 16.4 0.3 0.013 15.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Ribosomal_L3 PF00297.17 KEY66753.1 - 0.021 14.2 0.1 0.038 13.3 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L3 zf-C2H2_2 PF12756.2 KEY66753.1 - 0.023 14.8 0.1 0.041 13.9 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 KEY66753.1 - 0.043 13.6 0.3 0.083 12.6 0.2 1.5 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_jaz PF12171.3 KEY66753.1 - 0.09 12.9 0.3 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF3505 PF12013.3 KEY66753.1 - 0.18 12.0 2.3 0.14 12.4 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) Viral_P18 PF04521.8 KEY66753.1 - 6.5 6.2 7.8 0.29 10.5 1.1 1.9 2 1 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein F-box PF00646.28 KEY66754.1 - 4.3e-09 35.7 2.8 1.3e-08 34.2 0.1 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KEY66754.1 - 8.9e-07 28.5 0.4 8.9e-07 28.5 0.3 2.8 3 0 0 3 3 3 1 F-box-like RPEL PF02755.10 KEY66754.1 - 0.00046 19.4 0.0 0.054 12.8 0.0 2.8 2 0 0 2 2 2 1 RPEL repeat F-box-like_2 PF13013.1 KEY66754.1 - 0.9 9.2 4.2 9.4 6.0 2.9 2.2 1 1 0 1 1 1 0 F-box-like domain LAMTOR PF15454.1 KEY66756.1 - 8.4e-15 54.8 0.0 1.3e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator HSBP1 PF06825.7 KEY66759.1 - 0.0075 15.8 2.3 1.8 8.2 0.1 3.2 4 0 0 4 4 3 1 Heat shock factor binding protein 1 Vac_Fusion PF02346.11 KEY66759.1 - 0.012 14.9 2.8 0.95 8.9 0.2 2.5 2 0 0 2 2 2 0 Chordopoxvirus fusion protein HAUS-augmin3 PF14932.1 KEY66759.1 - 0.018 14.2 9.9 0.026 13.6 3.4 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4140 PF13600.1 KEY66759.1 - 0.024 15.0 12.5 0.037 14.4 0.3 2.9 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) NPV_P10 PF05531.7 KEY66759.1 - 0.025 14.8 4.5 0.45 10.7 0.2 2.7 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein TMF_DNA_bd PF12329.3 KEY66759.1 - 0.032 14.0 15.3 0.37 10.6 1.5 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Spectrin PF00435.16 KEY66759.1 - 0.034 14.4 14.9 0.87 9.9 0.9 3.2 2 1 1 3 3 3 0 Spectrin repeat Use1 PF09753.4 KEY66759.1 - 0.051 13.0 4.9 0.068 12.5 3.4 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 GST_C_2 PF13410.1 KEY66759.1 - 0.068 13.0 0.8 7.2 6.5 0.1 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Apolipoprotein PF01442.13 KEY66759.1 - 0.069 12.6 9.6 0.13 11.7 0.1 2.5 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Prefoldin_2 PF01920.15 KEY66759.1 - 0.094 12.4 12.5 0.098 12.4 0.3 3.0 2 1 0 2 2 2 0 Prefoldin subunit DUF1917 PF08939.5 KEY66759.1 - 0.1 12.3 3.0 0.14 11.9 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) Syntaxin-6_N PF09177.6 KEY66759.1 - 0.11 12.9 0.3 0.11 12.9 0.2 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF948 PF06103.6 KEY66759.1 - 0.11 12.3 1.1 3 7.7 0.2 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4164 PF13747.1 KEY66759.1 - 0.12 12.5 13.2 0.096 12.8 0.7 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4164) PspA_IM30 PF04012.7 KEY66759.1 - 0.13 11.5 0.1 0.13 11.5 0.1 2.8 2 1 1 3 3 3 0 PspA/IM30 family FlaC_arch PF05377.6 KEY66759.1 - 0.14 12.0 2.0 12 5.8 0.4 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FadA PF09403.5 KEY66759.1 - 0.18 11.8 12.2 0.84 9.6 1.1 2.5 1 1 1 2 2 2 0 Adhesion protein FadA AAA_23 PF13476.1 KEY66759.1 - 0.2 11.9 6.4 0.28 11.4 4.4 1.2 1 0 0 1 1 1 0 AAA domain MtrG PF04210.8 KEY66759.1 - 0.21 11.2 2.0 1.4 8.6 0.1 2.5 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G APG6 PF04111.7 KEY66759.1 - 0.22 10.5 11.0 1.2 8.1 4.8 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 Baculo_PEP_C PF04513.7 KEY66759.1 - 0.27 11.0 1.9 6.1 6.6 0.4 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.7 KEY66759.1 - 0.27 10.9 14.7 2.5 7.8 10.2 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein HWE_HK PF07536.9 KEY66759.1 - 0.4 11.1 5.2 3.5 8.1 1.1 2.3 2 0 0 2 2 2 0 HWE histidine kinase Acyl-CoA_dh_2 PF08028.6 KEY66759.1 - 0.44 10.8 3.6 0.35 11.1 1.2 1.8 1 1 1 2 2 1 0 Acyl-CoA dehydrogenase, C-terminal domain Fzo_mitofusin PF04799.8 KEY66759.1 - 0.59 9.4 4.2 1.1 8.6 0.0 2.3 2 1 0 2 2 2 0 fzo-like conserved region EMP24_GP25L PF01105.19 KEY66759.1 - 0.69 9.6 6.4 3.8 7.1 2.6 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Phage_Mu_Gam PF07352.7 KEY66759.1 - 0.71 9.3 8.8 0.67 9.4 2.7 2.0 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein DivIC PF04977.10 KEY66759.1 - 0.84 9.1 17.2 2.5 7.6 4.2 3.3 2 1 1 3 3 3 0 Septum formation initiator IncA PF04156.9 KEY66759.1 - 1.1 8.8 21.3 2.7 7.5 8.0 2.1 1 1 0 2 2 2 0 IncA protein bZIP_1 PF00170.16 KEY66759.1 - 1.1 9.2 12.7 0.23 11.4 0.5 3.1 3 0 0 3 3 3 0 bZIP transcription factor HSCB_C PF07743.8 KEY66759.1 - 1.4 9.4 13.9 4.1 7.9 2.9 2.9 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain DUF4298 PF14131.1 KEY66759.1 - 1.4 8.7 8.1 8.6 6.3 0.8 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4298) Uds1 PF15456.1 KEY66759.1 - 1.9 8.4 13.6 8.1e+02 -0.0 9.5 2.4 1 1 0 1 1 1 0 Up-regulated During Septation DUF342 PF03961.8 KEY66759.1 - 2.5 6.4 8.8 5.7 5.2 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Fib_alpha PF08702.5 KEY66759.1 - 3.1 7.9 11.1 28 4.8 0.1 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.1 KEY66759.1 - 3.1 6.6 11.9 6.1 5.7 7.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-Q PF13094.1 KEY66759.1 - 3.1 7.8 17.1 2.6e+02 1.5 11.8 2.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Pox_A_type_inc PF04508.7 KEY66759.1 - 3.8 7.5 8.6 30 4.7 1.9 3.7 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat PilJ PF13675.1 KEY66759.1 - 4.4 7.6 13.0 15 5.9 0.7 2.5 1 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Nsp1_C PF05064.8 KEY66759.1 - 4.7 6.8 10.1 5.3 6.7 0.3 2.9 2 2 1 3 3 3 0 Nsp1-like C-terminal region Cortex-I_coil PF09304.5 KEY66759.1 - 5 7.2 16.3 0.59 10.2 2.3 2.9 1 1 2 3 3 3 0 Cortexillin I, coiled coil Gal4_dimer PF03902.8 KEY66759.1 - 5.3 7.0 8.8 0.39 10.7 0.3 3.2 3 1 0 3 3 3 0 Gal4-like dimerisation domain DUF3186 PF11382.3 KEY66759.1 - 5.6 6.0 7.9 14 4.6 1.6 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3186) Atg14 PF10186.4 KEY66759.1 - 5.8 5.7 12.8 0.2 10.5 2.6 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Med21 PF11221.3 KEY66759.1 - 6.1 6.8 9.7 5.8 6.8 1.3 2.7 2 1 1 3 3 3 0 Subunit 21 of Mediator complex GAS PF13851.1 KEY66759.1 - 6.4 5.9 17.0 3.3 6.8 6.1 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Ax_dynein_light PF10211.4 KEY66759.1 - 9 6.0 15.7 13 5.5 1.4 3.0 2 1 1 3 3 3 0 Axonemal dynein light chain DUF1043 PF06295.7 KEY66759.1 - 9 5.9 7.8 2 8.0 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Exonuc_VII_L PF02601.10 KEY66759.1 - 9.6 5.2 13.7 1.9e+02 1.0 9.7 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit Herpes_UL6 PF01763.11 KEY66761.1 - 0.00093 17.4 1.0 0.0013 17.0 0.1 1.5 2 0 0 2 2 2 1 Herpesvirus UL6 like CENP-F_N PF10481.4 KEY66761.1 - 0.0044 16.4 0.9 0.39 10.0 0.1 2.2 2 0 0 2 2 2 1 Cenp-F N-terminal domain DUF342 PF03961.8 KEY66761.1 - 0.0047 15.3 1.3 0.29 9.5 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF342) TMF_DNA_bd PF12329.3 KEY66761.1 - 0.0065 16.2 2.3 0.71 9.7 0.1 2.7 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding IFT57 PF10498.4 KEY66761.1 - 0.0083 14.9 1.9 0.092 11.4 0.1 2.0 1 1 1 2 2 2 1 Intra-flagellar transport protein 57 DUF1110 PF06533.7 KEY66761.1 - 0.019 14.7 1.3 0.031 14.0 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) Med4 PF10018.4 KEY66761.1 - 0.022 14.1 1.2 0.029 13.7 0.1 1.7 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 FlgN PF05130.7 KEY66761.1 - 0.024 14.8 3.7 2.6 8.2 0.5 2.1 2 0 0 2 2 2 0 FlgN protein Fez1 PF06818.10 KEY66761.1 - 0.029 14.3 0.2 0.029 14.3 0.2 1.6 2 0 0 2 2 2 0 Fez1 Prefoldin_2 PF01920.15 KEY66761.1 - 0.038 13.7 0.1 7.1 6.4 0.0 2.6 2 0 0 2 2 2 0 Prefoldin subunit HTH_34 PF13601.1 KEY66761.1 - 0.041 13.9 0.5 1.7 8.7 0.0 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain TMF_TATA_bd PF12325.3 KEY66761.1 - 0.066 12.9 0.6 0.19 11.4 0.1 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2730 PF10805.3 KEY66761.1 - 0.12 12.1 0.1 24 4.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) CHASE3 PF05227.8 KEY66761.1 - 0.14 11.8 3.6 0.98 9.0 0.6 2.5 2 1 0 2 2 2 0 CHASE3 domain DUF3138 PF11336.3 KEY66761.1 - 0.32 9.1 3.0 0.46 8.6 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) bZIP_1 PF00170.16 KEY66761.1 - 5 7.1 6.8 3.9 7.4 0.0 3.0 3 0 0 3 3 3 0 bZIP transcription factor DUF336 PF03928.9 KEY66762.1 - 8.9e-20 70.8 0.3 1.1e-19 70.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Sugar_tr PF00083.19 KEY66763.1 - 1.6e-81 274.1 17.3 1.9e-81 273.9 12.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY66763.1 - 1.9e-27 95.8 19.3 2.7e-27 95.4 13.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KEY66763.1 - 2e-06 26.3 7.3 1.2e-05 23.7 1.9 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KEY66763.1 - 1.7e-05 23.4 0.6 1.7e-05 23.4 0.4 3.1 3 1 0 3 3 3 2 MFS/sugar transport protein OATP PF03137.15 KEY66763.1 - 0.003 15.6 1.2 0.0061 14.6 0.9 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Tmemb_170 PF10190.4 KEY66763.1 - 0.23 11.5 3.1 0.25 11.4 0.1 2.5 2 0 0 2 2 2 0 Putative transmembrane protein 170 Nuc_sug_transp PF04142.10 KEY66765.1 - 1.5e-78 263.2 3.9 2.3e-78 262.7 2.7 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 KEY66765.1 - 2.3e-09 37.0 21.7 4.7e-07 29.5 2.4 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 KEY66765.1 - 9.5e-07 28.8 5.6 9.5e-07 28.8 3.9 2.9 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 KEY66765.1 - 3.8e-05 23.8 2.4 3.8e-05 23.8 1.7 2.9 2 1 0 2 2 2 1 Multidrug resistance efflux transporter UAA PF08449.6 KEY66765.1 - 4.5e-05 22.5 16.0 7.4e-05 21.8 9.3 2.3 1 1 1 2 2 2 2 UAA transporter family NTP_transferase PF00483.18 KEY66766.1 - 1.1e-30 106.7 0.0 1.5e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 KEY66766.1 - 1.3e-09 37.1 7.7 6.5e-05 22.2 0.1 3.9 3 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KEY66766.1 - 2e-06 27.9 0.0 3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF459 PF04311.8 KEY66766.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF459) Hexapep_2 PF14602.1 KEY66766.1 - 0.77 9.3 3.7 2.5 7.7 0.0 3.1 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Dynamin_N PF00350.18 KEY66767.1 - 3.1e-22 79.1 0.0 1.2e-21 77.2 0.0 2.1 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KEY66767.1 - 1.5e-10 40.3 0.1 0.0001 21.1 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 KEY66767.1 - 1.1e-09 38.0 0.4 1.1e-09 38.0 0.3 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KEY66767.1 - 0.013 15.4 0.0 0.3 11.0 0.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.22 KEY66767.1 - 0.026 14.8 0.0 0.14 12.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter RICH PF05062.7 KEY66767.1 - 0.046 13.8 0.3 0.046 13.8 0.2 2.5 2 0 0 2 2 2 0 RICH domain DUF128 PF01995.11 KEY66767.1 - 0.068 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF128 Miro PF08477.8 KEY66767.1 - 0.069 13.6 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein MFS_1 PF07690.11 KEY66768.1 - 1e-36 126.3 31.4 1e-36 126.3 21.8 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY66768.1 - 8.3e-15 54.2 7.2 8.3e-15 54.2 5.0 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KEY66768.1 - 1.9e-08 32.9 3.9 1.9e-08 32.9 2.7 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1049 PF06305.6 KEY66768.1 - 1.5 8.3 8.6 4.8 6.7 0.1 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) SKG6 PF08693.5 KEY66769.1 - 1.2e-06 27.7 1.1 2e-06 26.9 0.7 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 KEY66769.1 - 2.6e-05 23.8 0.2 4.2e-05 23.1 0.2 1.3 1 0 0 1 1 1 1 Podoplanin Mucin PF01456.12 KEY66769.1 - 0.023 14.4 12.3 0.031 14.0 8.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein VSP PF03302.8 KEY66769.1 - 0.048 12.2 0.0 0.061 11.9 0.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Glyco_transf_25 PF01755.12 KEY66770.1 - 4.8e-20 72.0 0.0 6.2e-15 55.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF2244 PF10003.4 KEY66772.1 - 5.3 6.4 8.0 8.1 5.8 1.2 2.5 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) EphA2_TM PF14575.1 KEY66774.1 - 0.0094 16.3 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain LysE PF01810.13 KEY66774.1 - 0.045 13.0 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 LysE type translocator DUF1180 PF06679.7 KEY66774.1 - 0.069 13.0 0.2 0.069 13.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF2232 PF09991.4 KEY66774.1 - 0.089 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) ATP1G1_PLM_MAT8 PF02038.11 KEY66774.1 - 0.17 10.9 0.3 0.31 10.0 0.2 1.4 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Syndecan PF01034.15 KEY66774.1 - 0.17 11.5 0.6 0.34 10.5 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain Rifin_STEVOR PF02009.11 KEY66774.1 - 1.4 8.5 2.6 4.2 6.9 0.2 2.1 1 1 0 2 2 2 0 Rifin/stevor family TPR_MLP1_2 PF07926.7 KEY66775.1 - 1.6e-29 102.3 51.5 1.9e-29 102.0 21.2 17.1 8 5 7 15 15 15 5 TPR/MLP1/MLP2-like protein DUF3584 PF12128.3 KEY66775.1 - 2.3e-07 28.6 43.9 2.3e-07 28.6 30.4 10.1 2 2 7 10 10 10 2 Protein of unknown function (DUF3584) DUF904 PF06005.7 KEY66775.1 - 0.00014 22.0 7.5 0.00014 22.0 5.2 23.9 11 6 11 22 22 22 3 Protein of unknown function (DUF904) Filament PF00038.16 KEY66775.1 - 0.00028 20.4 15.9 0.00028 20.4 11.0 13.5 4 2 9 13 13 13 6 Intermediate filament protein KID PF02524.9 KEY66775.1 - 2 8.8 6.2 25 5.6 0.6 4.9 3 0 0 3 3 3 0 KID repeat DEAD PF00270.24 KEY66776.1 - 1.3e-40 138.6 0.0 4.3e-40 136.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY66776.1 - 2.6e-22 78.4 0.1 1e-21 76.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KEY66776.1 - 0.016 14.0 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.10 KEY66776.1 - 0.045 13.5 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Lactamase_B_2 PF12706.2 KEY66777.1 - 1.4e-08 34.5 0.0 2.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.9 KEY66777.1 - 2.1e-05 24.5 0.0 5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.22 KEY66777.1 - 5.8e-05 22.8 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 KEY66777.1 - 0.035 13.9 0.0 0.098 12.4 0.0 1.8 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase GMC_oxred_N PF00732.14 KEY66778.1 - 2e-21 76.4 0.0 4.2e-21 75.3 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY66778.1 - 4.6e-19 69.1 0.1 9e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KEY66778.1 - 1.2e-09 37.5 0.0 0.0004 19.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain CBM_1 PF00734.13 KEY66778.1 - 5.6e-08 32.3 5.1 5.6e-08 32.3 3.5 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain DAO PF01266.19 KEY66778.1 - 3e-06 26.3 1.1 0.00024 20.1 0.3 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY66778.1 - 9.2e-05 22.3 0.0 0.00024 21.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KEY66778.1 - 0.0013 18.7 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEY66778.1 - 0.002 16.7 0.0 0.003 16.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 KEY66778.1 - 0.0086 16.1 0.1 0.021 14.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEY66778.1 - 0.0095 15.0 0.1 0.018 14.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KEY66778.1 - 0.02 13.9 1.9 0.7 8.8 0.0 3.2 4 0 0 4 4 4 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KEY66778.1 - 0.029 13.4 0.1 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 KEY66778.1 - 0.052 12.4 0.0 0.078 11.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 KEY66778.1 - 0.11 12.9 0.0 0.47 10.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_11 PF00457.12 KEY66779.1 - 1e-79 266.1 20.1 1.4e-79 265.6 13.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 PMI_typeI PF01238.16 KEY66779.1 - 7.2e-75 252.2 0.0 1.1e-74 251.6 0.0 1.3 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 KEY66779.1 - 0.0038 16.9 0.0 0.078 12.6 0.0 2.5 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.6 KEY66779.1 - 0.0084 15.5 0.1 2.8 7.4 0.0 2.5 2 0 0 2 2 2 2 Cupin domain eIF-4B PF06273.6 KEY66779.1 - 0.88 8.2 6.8 1.3 7.6 4.7 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B PTR2 PF00854.16 KEY66780.1 - 1e-26 93.6 7.2 2.4e-15 56.2 0.5 2.3 1 1 1 2 2 2 2 POT family ATP-grasp_4 PF13535.1 KEY66781.1 - 6.3e-16 58.6 0.0 2.3e-14 53.5 0.0 2.7 2 1 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KEY66781.1 - 0.0096 15.3 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus PALP PF00291.20 KEY66782.1 - 1.2e-16 60.7 0.0 1.5e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme gp37_C PF12604.3 KEY66782.1 - 0.092 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Tail fiber protein gp37 C terminal adh_short PF00106.20 KEY66783.1 - 3.1e-18 66.2 0.4 4.9e-18 65.5 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY66783.1 - 1.9e-12 47.2 0.2 2.6e-12 46.7 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY66783.1 - 1.8e-08 34.4 0.0 1.3e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KEY66783.1 - 0.021 14.8 0.1 0.033 14.1 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 KEY66783.1 - 0.049 13.7 0.0 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 KEY66783.1 - 0.082 11.8 0.0 0.47 9.3 0.0 2.1 1 1 0 1 1 1 0 Male sterility protein YjeF_N PF03853.10 KEY66783.1 - 0.1 12.2 0.1 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus DUF2417 PF10329.4 KEY66785.1 - 4.4e-83 278.2 2.0 5.6e-83 277.9 1.4 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 KEY66785.1 - 2.1e-06 27.8 1.3 3.7e-06 26.9 0.4 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Scs3p PF10261.4 KEY66785.1 - 0.12 11.3 2.9 0.44 9.5 0.0 2.3 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF2975 PF11188.3 KEY66785.1 - 1 9.0 13.2 0.77 9.4 4.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) RhoGAP PF00620.22 KEY66786.1 - 5.5e-35 120.2 0.0 1.2e-34 119.1 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KEY66786.1 - 2.1e-29 101.3 37.7 3.3e-11 43.0 5.2 4.8 5 0 0 5 5 5 4 LIM domain zf-ribbon_3 PF13248.1 KEY66786.1 - 2.1 7.6 18.1 2.8 7.2 0.1 4.3 4 0 0 4 4 4 0 zinc-ribbon domain 3Beta_HSD PF01073.14 KEY66787.1 - 7.7e-64 215.0 0.0 9.4e-64 214.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KEY66787.1 - 7.2e-28 97.6 0.0 1.1e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KEY66787.1 - 1.5e-17 63.4 0.1 2.1e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KEY66787.1 - 1.1e-13 50.7 0.1 1.5e-11 43.7 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KEY66787.1 - 2.1e-13 50.6 0.1 2.8e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KEY66787.1 - 5e-06 25.6 0.0 5.5e-05 22.2 0.0 2.5 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KEY66787.1 - 0.00016 21.6 0.6 0.00051 20.0 0.4 1.8 1 1 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 KEY66787.1 - 0.011 15.5 0.0 0.027 14.3 0.0 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF3315 PF11776.3 KEY66787.1 - 0.029 13.8 0.0 0.071 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3315) AA_kinase PF00696.23 KEY66787.1 - 0.041 13.4 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Amino acid kinase family HMG_box PF00505.14 KEY66789.1 - 1.7e-06 28.1 1.6 0.00055 20.1 0.2 4.0 3 2 1 4 4 4 2 HMG (high mobility group) box SR-25 PF10500.4 KEY66789.1 - 0.072 12.5 23.3 0.15 11.5 16.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 KEY66789.1 - 0.16 11.3 27.9 0.013 14.8 15.4 1.9 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Med19 PF10278.4 KEY66789.1 - 0.28 10.8 12.5 0.66 9.6 8.6 1.7 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Ycf1 PF05758.7 KEY66789.1 - 0.54 7.8 4.9 0.65 7.6 3.4 1.2 1 0 0 1 1 1 0 Ycf1 CDC27 PF09507.5 KEY66789.1 - 8.6 5.4 28.7 3.9 6.6 17.8 1.7 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Proteasome PF00227.21 KEY66790.1 - 1.3e-31 109.4 0.0 1.5e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit SIS PF01380.17 KEY66791.1 - 3.9e-50 168.8 0.3 6.2e-30 103.4 0.1 3.3 3 0 0 3 3 3 3 SIS domain GATase_2 PF00310.16 KEY66791.1 - 1.5e-26 93.0 0.0 5.6e-18 64.7 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KEY66791.1 - 7.2e-20 71.2 0.0 1.6e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KEY66791.1 - 1.5e-11 44.1 0.0 3.7e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KEY66791.1 - 6.5e-08 31.5 0.0 1e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 KEY66791.1 - 0.062 13.0 0.0 0.33 10.6 0.0 2.2 2 0 0 2 2 2 0 SIS domain AAA PF00004.24 KEY66792.1 - 5.2e-43 146.4 0.0 8.8e-43 145.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEY66792.1 - 7.8e-08 32.5 0.1 5.7e-06 26.4 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 KEY66792.1 - 1.6e-06 27.8 0.1 3.7e-05 23.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KEY66792.1 - 2.8e-06 27.3 0.0 7.7e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KEY66792.1 - 2.9e-06 27.4 0.0 0.001 19.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 KEY66792.1 - 7.4e-06 25.1 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 KEY66792.1 - 0.00019 20.4 0.0 0.00054 18.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 KEY66792.1 - 0.00031 20.4 0.0 0.00075 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KEY66792.1 - 0.00043 21.0 0.4 0.0021 18.8 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KEY66792.1 - 0.0013 18.6 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KEY66792.1 - 0.0016 17.2 0.0 0.0031 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 KEY66792.1 - 0.0017 18.2 0.0 0.0063 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KEY66792.1 - 0.0021 17.5 0.2 0.0054 16.1 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.1 KEY66792.1 - 0.0023 18.2 0.3 0.0081 16.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KEY66792.1 - 0.0031 16.6 0.0 0.0063 15.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KEY66792.1 - 0.0048 17.0 0.0 0.0096 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 KEY66792.1 - 0.0051 15.9 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 KEY66792.1 - 0.0071 15.7 0.1 0.046 13.1 0.1 2.2 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KEY66792.1 - 0.0075 15.7 0.0 0.025 14.0 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 KEY66792.1 - 0.0079 15.7 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 KEY66792.1 - 0.0089 15.6 0.4 0.25 10.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF4200 PF13863.1 KEY66792.1 - 0.013 15.4 2.5 0.013 15.4 1.8 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) AAA_24 PF13479.1 KEY66792.1 - 0.019 14.5 0.1 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KEY66792.1 - 0.019 14.8 0.2 0.047 13.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain KaiC PF06745.8 KEY66792.1 - 0.021 13.9 0.4 0.098 11.7 0.0 2.3 3 0 0 3 3 3 0 KaiC Sigma54_activ_2 PF14532.1 KEY66792.1 - 0.024 14.6 0.0 0.064 13.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.10 KEY66792.1 - 0.024 14.4 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 KEY66792.1 - 0.026 14.2 0.1 0.14 11.8 0.0 2.2 2 1 0 2 2 2 0 Archaeal ATPase PhoH PF02562.11 KEY66792.1 - 0.03 13.5 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 KEY66792.1 - 0.04 13.5 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 KEY66792.1 - 0.048 13.3 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 KEY66792.1 - 0.051 13.8 1.4 3.5 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KEY66792.1 - 0.076 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 KEY66792.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Mago-bind PF09282.5 KEY66793.1 - 7.8e-15 54.1 3.8 1.7e-14 53.0 2.6 1.6 1 0 0 1 1 1 1 Mago binding Dsh_C PF12316.3 KEY66793.1 - 0.025 14.7 0.7 0.029 14.5 0.5 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal GET2 PF08690.5 KEY66793.1 - 0.3 10.2 2.0 0.37 10.0 1.4 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 UCR_UQCRX_QCR9 PF05365.7 KEY66794.1 - 1.1e-20 73.0 1.0 1.5e-20 72.5 0.7 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-UBR PF02207.15 KEY66795.1 - 1.7e-17 62.8 16.7 4.7e-17 61.4 11.6 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 KEY66795.1 - 1.1e-07 31.4 0.1 2.4e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS CRC_subunit PF08624.5 KEY66796.1 - 4.7e-59 198.2 0.0 8.1e-59 197.5 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Ebola_NP PF05505.7 KEY66796.1 - 0.15 10.0 9.2 0.22 9.5 6.4 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein CDC45 PF02724.9 KEY66796.1 - 8.7 4.2 5.5 12 3.7 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Cyclin PF08613.6 KEY66797.1 - 5.1e-13 49.6 0.0 9e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KEY66797.1 - 0.00044 19.8 0.3 0.0017 17.8 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Nefa_Nip30_N PF10187.4 KEY66798.1 - 1.8e-22 79.4 21.7 1.8e-22 79.4 15.0 2.8 2 2 1 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 MIF4G_like_2 PF09090.6 KEY66798.1 - 7.9 5.6 8.9 14 4.7 6.1 1.3 1 0 0 1 1 1 0 MIF4G like Tim54 PF11711.3 KEY66799.1 - 2.6e-112 375.2 0.4 3.2e-112 374.9 0.3 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.20 KEY66800.1 - 2.3e-55 187.5 0.1 7e-39 133.5 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEY66800.1 - 1.6e-25 89.6 0.1 2.3e-19 69.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 KEY66800.1 - 0.00011 21.3 0.0 0.00028 20.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KEY66800.1 - 0.00031 19.8 0.4 0.00059 18.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KEY66800.1 - 0.0045 16.7 3.3 0.016 14.9 0.2 2.6 2 1 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KEY66800.1 - 0.065 12.0 0.1 0.1 11.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_C PF00433.19 KEY66800.1 - 0.086 13.3 0.2 0.086 13.3 0.2 2.0 2 0 0 2 2 2 0 Protein kinase C terminal domain Seadorna_VP7 PF07387.6 KEY66800.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 zf-met PF12874.2 KEY66801.1 - 8e-06 25.8 1.0 1.4e-05 25.1 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 KEY66801.1 - 3.4e-05 23.4 0.2 5.2e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein GN3L_Grn1 PF08701.6 KEY66802.1 - 6.9e-24 83.5 20.6 1.3e-23 82.6 14.3 1.5 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 KEY66802.1 - 3.6e-20 72.0 0.1 6.6e-14 51.8 0.0 2.9 2 1 1 3 3 3 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEY66802.1 - 2.7e-07 30.1 0.0 0.013 14.9 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KEY66802.1 - 5.5e-05 23.0 10.4 0.074 12.8 0.0 4.1 4 1 0 4 4 4 2 Dynamin family DUF258 PF03193.11 KEY66802.1 - 0.00011 21.4 0.2 0.00019 20.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ORC3_N PF07034.6 KEY66802.1 - 0.0024 16.9 0.0 0.0043 16.0 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus FeoB_N PF02421.13 KEY66802.1 - 0.0044 16.3 0.4 0.083 12.1 0.1 2.6 2 1 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 KEY66802.1 - 0.012 16.0 3.2 2.1 8.8 0.1 2.8 3 0 0 3 3 3 0 Miro-like protein Nop14 PF04147.7 KEY66802.1 - 0.58 8.0 27.8 1.1 7.0 19.3 1.4 1 0 0 1 1 1 0 Nop14-like family AAA_16 PF13191.1 KEY66802.1 - 0.62 10.0 4.3 0.32 10.9 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain ArgK PF03308.11 KEY66802.1 - 1.1 7.9 6.4 0.13 10.9 0.1 2.1 2 0 0 2 2 2 0 ArgK protein SGT1 PF07093.6 KEY66802.1 - 5.8 5.1 19.3 8.1 4.6 13.4 1.1 1 0 0 1 1 1 0 SGT1 protein RNB PF00773.14 KEY66803.1 - 9.4e-96 320.8 0.0 1.4e-95 320.3 0.0 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 KEY66803.1 - 1.8e-06 28.0 0.4 8.5e-06 25.9 0.1 2.4 2 1 0 2 2 2 1 PIN domain OB_RNB PF08206.6 KEY66803.1 - 0.1 12.1 0.0 0.29 10.6 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease B OB domain CRC_subunit PF08624.5 KEY66804.1 - 2.7e-53 179.5 0.0 3.7e-53 179.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit CBFD_NFYB_HMF PF00808.18 KEY66806.1 - 1.9e-09 37.4 0.0 3.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KEY66806.1 - 0.0012 18.8 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SKG6 PF08693.5 KEY66807.1 - 0.0048 16.1 0.0 0.0079 15.4 0.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 KEY66807.1 - 0.09 12.4 1.1 0.47 10.1 0.3 2.0 1 1 1 2 2 2 0 TMEM154 protein family Kelch_5 PF13854.1 KEY66809.1 - 1.8e-12 46.9 12.5 9.3e-08 31.8 0.0 5.7 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.1 KEY66809.1 - 4.6e-07 29.4 16.1 0.13 12.0 0.1 7.8 7 1 0 7 7 7 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KEY66809.1 - 8.5e-06 25.7 10.8 0.89 9.8 0.1 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.1 KEY66809.1 - 0.0022 18.0 12.4 2.2 8.5 0.2 6.0 5 1 0 5 5 5 2 Galactose oxidase, central domain Adeno_E3_CR2 PF02439.10 KEY66809.1 - 0.048 13.2 1.7 0.097 12.2 1.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Kelch_1 PF01344.20 KEY66809.1 - 0.19 11.2 6.6 11 5.6 0.0 4.3 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.10 KEY66809.1 - 0.21 11.3 11.3 18 5.3 0.0 5.6 7 1 0 7 7 7 0 Kelch motif Syndecan PF01034.15 KEY66809.1 - 0.26 10.9 0.8 0.54 9.9 0.5 1.4 1 0 0 1 1 1 0 Syndecan domain DUF2376 PF09550.5 KEY66810.1 - 0.074 13.2 0.2 0.32 11.1 0.2 2.2 1 0 0 1 1 1 0 Conserved hypothetical phage protein (DUF2376) SYF2 PF08231.7 KEY66811.1 - 1.5e-50 171.2 16.0 2.7e-50 170.4 11.1 1.4 1 0 0 1 1 1 1 SYF2 splicing factor DUF1179 PF06678.6 KEY66811.1 - 1.6 9.0 4.4 0.65 10.3 0.5 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1179) NAD_binding_10 PF13460.1 KEY66812.1 - 9.3e-13 48.5 0.0 4.5e-12 46.3 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEY66812.1 - 8.3e-07 28.6 0.0 1.7e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEY66812.1 - 9.1e-05 21.2 0.0 0.00015 20.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KEY66812.1 - 0.00091 19.1 0.0 0.043 13.7 0.0 2.3 1 1 1 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KEY66812.1 - 0.0069 15.3 0.1 0.27 10.1 0.0 2.5 2 2 0 2 2 2 1 Male sterility protein YEATS PF03366.11 KEY66813.1 - 3.3e-28 97.2 0.1 5.1e-28 96.6 0.1 1.3 1 0 0 1 1 1 1 YEATS family DUF2404 PF10296.4 KEY66814.1 - 0.0011 19.0 0.0 0.0067 16.5 0.0 2.2 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Ins_P5_2-kin PF06090.7 KEY66815.1 - 7.3e-35 120.4 0.0 5.2e-33 114.4 0.0 2.1 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Nucleoside_tran PF01733.13 KEY66816.1 - 7.2e-37 127.1 5.6 7.2e-37 127.1 3.9 2.3 2 1 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.11 KEY66816.1 - 2.7e-05 23.0 35.0 0.001 17.8 4.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily NfeD PF01957.13 KEY66816.1 - 0.055 13.6 0.2 0.055 13.6 0.1 3.4 4 0 0 4 4 4 0 NfeD-like C-terminal, partner-binding DUF2786 PF10979.3 KEY66816.1 - 0.85 9.3 0.0 0.85 9.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2786) Catalase PF00199.14 KEY66817.1 - 4.6e-157 522.6 1.1 5.8e-157 522.2 0.8 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KEY66817.1 - 2.9e-17 62.2 0.0 5.3e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive SNF2_N PF00176.18 KEY66819.1 - 1e-22 80.2 0.0 1.7e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HET PF06985.6 KEY66819.1 - 2.9e-22 79.3 0.0 1.1e-21 77.4 0.0 2.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DEAD PF00270.24 KEY66819.1 - 0.013 15.0 0.0 0.037 13.5 0.0 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase EF_TS PF00889.14 KEY66819.1 - 0.36 10.1 0.2 2.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Elongation factor TS Glyco_hydro_39 PF01229.12 KEY66820.1 - 5.3e-106 354.9 0.0 1.4e-105 353.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 39 Glyco_hydro_cc PF11790.3 KEY66820.1 - 0.013 14.9 0.0 0.05 13.0 0.0 1.9 1 1 0 1 1 1 0 Glycosyl hydrolase catalytic core Melibiase PF02065.13 KEY66821.1 - 9.4e-39 133.2 0.0 2.5e-38 131.8 0.0 1.7 2 0 0 2 2 2 1 Melibiase Polysacc_lyase PF14099.1 KEY66822.1 - 1e-16 61.3 0.1 1.2e-16 61.0 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide lyase DND1_DSRM PF14709.1 KEY66823.1 - 0.048 13.9 0.1 0.093 13.0 0.1 1.5 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 KEY66823.1 - 0.1 13.2 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif Zn_clus PF00172.13 KEY66824.1 - 0.003 17.4 7.7 0.0062 16.4 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BRAP2 PF07576.7 KEY66825.1 - 8.2e-21 73.6 0.0 1.5e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 KEY66825.1 - 6.4e-18 64.6 8.4 1.6e-17 63.3 5.8 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 KEY66825.1 - 2.4e-10 40.0 9.8 2.4e-10 40.0 6.8 2.1 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 KEY66825.1 - 8.3e-06 25.4 8.6 8.3e-06 25.4 6.0 1.9 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KEY66825.1 - 4e-05 23.1 10.3 9.4e-05 21.9 7.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEY66825.1 - 7.2e-05 22.3 7.0 7.2e-05 22.3 4.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEY66825.1 - 0.0022 18.0 4.4 0.0022 18.0 3.0 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KEY66825.1 - 0.003 17.5 10.6 0.003 17.5 7.3 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) FlgN PF05130.7 KEY66825.1 - 0.015 15.5 7.9 0.025 14.8 5.4 1.3 1 0 0 1 1 1 0 FlgN protein bZIP_2 PF07716.10 KEY66825.1 - 0.037 13.8 0.9 0.037 13.8 0.7 2.6 2 0 0 2 2 2 0 Basic region leucine zipper HALZ PF02183.13 KEY66825.1 - 0.04 13.6 0.7 0.04 13.6 0.5 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper zf-RING_UBOX PF13445.1 KEY66825.1 - 0.049 13.3 8.5 0.051 13.3 2.2 2.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.1 KEY66825.1 - 0.064 13.0 4.4 0.15 11.8 3.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein HOOK PF05622.7 KEY66825.1 - 0.069 10.9 8.1 0.1 10.3 5.6 1.2 1 0 0 1 1 1 0 HOOK protein Baculo_RING PF05883.6 KEY66825.1 - 0.076 12.8 1.2 0.17 11.7 0.8 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain bZIP_1 PF00170.16 KEY66825.1 - 0.082 12.8 0.4 0.082 12.8 0.2 2.1 2 0 0 2 2 2 0 bZIP transcription factor DUF745 PF05335.8 KEY66825.1 - 0.093 12.2 6.6 0.17 11.3 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Cauli_AT PF03233.8 KEY66825.1 - 0.37 10.4 1.5 0.63 9.7 1.0 1.3 1 0 0 1 1 1 0 Aphid transmission protein AAA_13 PF13166.1 KEY66825.1 - 0.84 8.0 6.5 1.2 7.5 4.5 1.1 1 0 0 1 1 1 0 AAA domain DUF904 PF06005.7 KEY66825.1 - 1.7 9.0 13.0 0.72 10.1 2.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF904) IncA PF04156.9 KEY66825.1 - 5.4 6.5 8.9 19 4.7 6.2 1.9 1 1 0 1 1 1 0 IncA protein Lyase_1 PF00206.15 KEY66826.1 - 2.6e-86 289.6 0.0 3.7e-86 289.1 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 KEY66826.1 - 9.9e-28 96.0 0.1 2.9e-27 94.5 0.1 1.9 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal WES_acyltransf PF03007.11 KEY66826.1 - 0.062 12.8 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Acyltransferase PF01553.16 KEY66827.1 - 1.2e-10 40.9 0.0 5.2e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase Suc_Fer-like PF06999.7 KEY66828.1 - 2.8e-35 122.3 0.0 3.9e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF4577 PF15145.1 KEY66830.1 - 0.014 15.2 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) Chromo_shadow PF01393.14 KEY66831.1 - 5.9e-14 51.6 0.6 4e-12 45.7 0.0 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.19 KEY66831.1 - 1.8e-12 46.6 0.6 1.8e-12 46.6 0.4 2.7 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain HALZ PF02183.13 KEY66832.1 - 0.00055 19.5 2.4 0.0021 17.7 1.7 2.0 1 0 0 1 1 1 1 Homeobox associated leucine zipper zf-Di19 PF05605.7 KEY66832.1 - 0.0081 16.2 1.2 0.023 14.8 0.0 2.3 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding DivIC PF04977.10 KEY66832.1 - 0.014 14.8 1.9 0.014 14.8 1.3 2.5 3 1 0 3 3 3 0 Septum formation initiator zf-C2HC_2 PF13913.1 KEY66832.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 KEY66832.1 - 0.11 12.8 0.1 0.29 11.5 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-ribbon_3 PF13248.1 KEY66832.1 - 0.13 11.5 0.3 0.23 10.6 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Chibby PF14645.1 KEY66832.1 - 0.27 11.1 4.8 0.054 13.3 0.5 2.0 2 0 0 2 2 2 0 Chibby family Laminin_II PF06009.7 KEY66832.1 - 0.57 9.9 7.8 9.3 6.0 0.0 4.2 4 0 0 4 4 4 0 Laminin Domain II bZIP_1 PF00170.16 KEY66832.1 - 1.1 9.3 9.9 0.12 12.3 2.9 2.3 2 0 0 2 2 2 0 bZIP transcription factor zf-CHCC PF10276.4 KEY66832.1 - 3.1 7.6 4.3 1.3 8.9 0.2 2.4 3 0 0 3 3 3 0 Zinc-finger domain COX15-CtaA PF02628.10 KEY66833.1 - 1.8e-95 319.3 9.3 2.2e-95 318.9 6.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Utp14 PF04615.8 KEY66834.1 - 3e-168 561.2 63.5 3e-168 561.2 44.0 2.4 1 1 1 2 2 2 1 Utp14 protein Na_Ca_ex PF01699.19 KEY66835.1 - 5.8e-47 158.8 35.8 1.6e-24 86.1 8.9 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF4131 PF13567.1 KEY66835.1 - 0.39 10.0 0.0 0.39 10.0 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) Glyco_hydro_81 PF03639.8 KEY66837.1 - 4.3e-202 672.8 1.8 5e-202 672.6 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 DUF1914 PF08932.5 KEY66837.1 - 0.037 14.0 0.1 7.2 6.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1914) Stn1 PF10451.4 KEY66838.1 - 1.8e-11 43.3 0.0 3.6e-11 42.3 0.0 1.4 1 1 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 KEY66838.1 - 0.00013 21.7 0.2 0.00025 20.8 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2235 PF09994.4 KEY66838.1 - 0.33 10.2 2.0 0.57 9.5 1.0 1.7 1 1 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DnaJ PF00226.26 KEY66839.1 - 7.7e-25 86.4 2.1 1.9e-24 85.1 1.4 1.7 1 0 0 1 1 1 1 DnaJ domain NUT_C PF12882.2 KEY66839.1 - 0.002 17.7 2.7 0.0038 16.8 1.9 1.4 1 0 0 1 1 1 1 NUT protein C terminal dCMP_cyt_deam_1 PF00383.17 KEY66840.1 - 1.8e-13 50.0 0.0 2.2e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Glyco_hydro_67N PF03648.9 KEY66841.1 - 0.00036 20.5 0.0 0.00085 19.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Piwi PF02171.12 KEY66842.1 - 1.7e-67 227.5 0.0 3.3e-67 226.6 0.0 1.4 2 0 0 2 2 2 1 Piwi domain PAZ PF02170.17 KEY66842.1 - 6.9e-08 31.8 0.0 1.4e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KEY66842.1 - 6.2e-07 28.6 0.1 2.8e-06 26.6 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) Abhydrolase_6 PF12697.2 KEY66843.1 - 1.2e-25 90.7 0.2 1.8e-25 90.1 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY66843.1 - 0.0012 18.6 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY66843.1 - 0.0069 15.9 0.0 0.047 13.2 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.9 KEY66843.1 - 0.012 14.1 0.0 0.018 13.4 0.0 1.2 1 0 0 1 1 1 0 Ndr family MFS_1 PF07690.11 KEY66845.1 - 1.5e-40 139.0 51.5 3.4e-40 137.8 35.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY66845.1 - 0.0028 16.2 15.2 0.0028 16.2 10.5 3.2 3 2 0 3 3 3 2 Sugar (and other) transporter Gryzun PF07919.7 KEY66846.1 - 8.3e-89 298.3 0.0 1.1e-88 297.9 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 KEY66846.1 - 4.5e-73 245.7 5.8 1.6e-70 237.4 2.1 2.3 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 KEY66846.1 - 0.0011 18.7 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking MRP-L27 PF09809.4 KEY66847.1 - 3.5e-15 55.5 0.7 5.1e-15 55.0 0.5 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Abhydrolase_3 PF07859.8 KEY66848.1 - 5.8e-40 137.1 0.0 3.6e-30 105.1 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KEY66848.1 - 7.8e-14 51.0 0.0 5.4e-13 48.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) COesterase PF00135.23 KEY66848.1 - 0.00011 21.0 0.0 0.039 12.6 0.0 2.4 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 KEY66848.1 - 0.00035 20.3 0.0 0.00067 19.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family CENP-U PF13097.1 KEY66848.1 - 1.3 8.9 9.6 8.3 6.3 0.7 2.7 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit WGG PF10273.4 KEY66849.1 - 2.1e-32 111.0 0.1 5.9e-32 109.6 0.0 1.7 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 KEY66849.1 - 0.49 10.4 0.1 0.49 10.4 0.1 2.3 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) BSD PF03909.12 KEY66850.1 - 8.6e-16 57.4 0.3 2.8e-15 55.7 0.1 2.0 2 0 0 2 2 2 1 BSD domain ALIX_LYPXL_bnd PF13949.1 KEY66850.1 - 0.0022 17.0 7.9 0.0052 15.7 2.4 2.3 1 1 1 2 2 2 2 ALIX V-shaped domain binding to HIV DUF2823 PF11034.3 KEY66851.1 - 1.6e-31 108.2 8.8 1.8e-31 108.0 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) DUF1102 PF06510.6 KEY66851.1 - 0.04 13.7 0.4 0.044 13.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1102) PAP1 PF08601.5 KEY66852.1 - 6.5e-42 144.4 16.1 1.2e-28 100.8 9.3 3.7 2 1 2 4 4 3 2 Transcription factor PAP1 bZIP_1 PF00170.16 KEY66852.1 - 2.6e-09 36.8 11.1 6.2e-09 35.6 7.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF812 PF05667.6 KEY66852.1 - 0.0043 15.6 5.5 0.0061 15.1 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) MbeD_MobD PF04899.7 KEY66852.1 - 0.0055 16.5 2.1 0.012 15.5 1.5 1.5 1 0 0 1 1 1 1 MbeD/MobD like DUF4618 PF15397.1 KEY66852.1 - 0.0095 15.3 6.1 0.015 14.6 4.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) bZIP_Maf PF03131.12 KEY66852.1 - 0.018 15.3 10.3 0.037 14.3 7.1 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Adeno_PIX PF03955.9 KEY66852.1 - 0.02 15.3 1.6 0.02 15.3 1.1 2.6 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) bZIP_2 PF07716.10 KEY66852.1 - 0.023 14.4 14.2 0.084 12.7 9.8 1.9 1 1 0 1 1 1 0 Basic region leucine zipper TMF_DNA_bd PF12329.3 KEY66852.1 - 0.072 12.8 8.9 0.15 11.8 6.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 KEY66852.1 - 0.083 13.2 3.6 0.18 12.1 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) dsrm PF00035.20 KEY66852.1 - 0.095 13.2 0.0 0.31 11.6 0.0 1.8 1 0 0 1 1 1 0 Double-stranded RNA binding motif HrpB7 PF09486.5 KEY66852.1 - 0.11 12.4 5.3 0.22 11.4 3.7 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Herpes_UL6 PF01763.11 KEY66852.1 - 0.52 8.4 3.0 0.77 7.8 2.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like CENP-H PF05837.7 KEY66852.1 - 0.95 9.6 6.5 2 8.6 4.5 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) IncA PF04156.9 KEY66852.1 - 1.2 8.7 6.4 1.9 8.0 4.4 1.2 1 0 0 1 1 1 0 IncA protein XhlA PF10779.4 KEY66852.1 - 2.6 8.0 5.9 4.9 7.1 4.1 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Bap31 PF05529.7 KEY66852.1 - 3.7 6.9 5.7 6.2 6.2 3.9 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Pkinase PF00069.20 KEY66853.1 - 1.5e-57 194.6 0.0 2.2e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY66853.1 - 2.6e-31 108.6 0.0 3.5e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY66853.1 - 9.4e-05 21.5 0.0 0.00015 20.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEY66853.1 - 0.012 15.3 0.5 0.012 15.3 0.3 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KEY66853.1 - 0.092 11.7 0.2 0.2 10.7 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SGL PF08450.7 KEY66855.1 - 2e-70 236.9 0.3 2.4e-70 236.7 0.2 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Reg_prop PF07494.6 KEY66855.1 - 0.0058 16.4 2.1 1 9.6 0.3 3.6 3 0 0 3 3 3 1 Two component regulator propeller Str_synth PF03088.11 KEY66855.1 - 0.015 15.3 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Strictosidine synthase Arylesterase PF01731.15 KEY66855.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Arylesterase adh_short PF00106.20 KEY66856.1 - 8.7e-29 100.5 0.6 1.8e-28 99.5 0.4 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY66856.1 - 1.6e-17 64.0 0.0 3.4e-15 56.4 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY66856.1 - 1.6e-14 53.9 0.3 3.2e-14 52.9 0.2 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY66856.1 - 0.00032 20.2 0.0 0.0042 16.5 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PAPS_reduct PF01507.14 KEY66857.1 - 5.4e-23 81.6 0.0 3.3e-17 62.8 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family DUF3632 PF12311.3 KEY66858.1 - 1.3e-39 135.8 4.6 1.8e-39 135.4 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) ubiquitin PF00240.18 KEY66858.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family zf-RING_2 PF13639.1 KEY66859.1 - 6.3e-10 38.7 5.9 9.8e-10 38.1 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEY66859.1 - 2.5e-08 33.8 2.0 4.5e-08 33.0 1.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KEY66859.1 - 6.7e-06 25.8 3.0 2.7e-05 23.9 2.1 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 KEY66859.1 - 0.0032 17.0 4.0 0.0065 16.1 2.8 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEY66859.1 - 0.07 12.7 4.4 0.12 12.0 3.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KEY66859.1 - 0.071 12.7 2.6 0.1 12.2 0.3 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 KEY66859.1 - 0.086 12.8 6.9 0.15 12.1 4.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 KEY66859.1 - 0.13 12.0 1.1 0.18 11.5 0.2 1.6 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_5 PF14634.1 KEY66859.1 - 0.4 10.4 3.3 1.1 9.0 2.4 1.6 1 1 1 2 2 2 0 zinc-RING finger domain NAD_binding_10 PF13460.1 KEY66860.1 - 4.5e-10 39.8 1.9 6e-10 39.4 1.3 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEY66860.1 - 5.9e-10 38.9 0.0 1.3e-09 37.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KEY66860.1 - 3.5e-05 23.1 0.0 5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KEY66860.1 - 0.0083 15.0 0.0 0.19 10.6 0.0 2.5 1 1 0 2 2 2 1 Male sterility protein HIM1 PF08732.5 KEY66860.1 - 0.0086 14.5 0.0 0.026 12.9 0.0 1.7 2 0 0 2 2 2 1 HIM1 DUF1471 PF07338.8 KEY66860.1 - 0.082 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) Flavokinase PF01687.12 KEY66861.1 - 3.8e-39 133.4 0.0 4.5e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase PAS PF00989.19 KEY66862.1 - 0.00083 19.1 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.13 KEY66862.1 - 0.014 15.3 9.6 0.014 15.3 6.7 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KEY66863.1 - 3e-36 124.8 34.3 3e-36 124.8 23.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY66863.1 - 1.8e-06 26.7 12.6 1.8e-06 26.7 8.7 2.7 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KEY66863.1 - 1.5e-05 23.3 2.1 2.7e-05 22.5 1.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cellulase PF00150.13 KEY66864.1 - 2.1e-13 50.1 0.1 2.1e-13 50.1 0.0 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) EphA2_TM PF14575.1 KEY66864.1 - 0.0059 16.9 0.1 0.023 15.0 0.0 2.0 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DUF1510 PF07423.6 KEY66864.1 - 0.12 11.7 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) P12 PF12669.2 KEY66864.1 - 0.2 11.8 0.1 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 Virus attachment protein p12 family SpoIIIAH PF12685.2 KEY66864.1 - 0.83 9.1 0.0 0.83 9.1 0.0 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein Transket_pyr PF02779.19 KEY66865.1 - 4.1e-43 146.9 0.0 1.1e-42 145.5 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KEY66865.1 - 1.1e-30 106.1 0.1 2.8e-30 104.7 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain F-actin_cap_A PF01267.12 KEY66866.1 - 2.8e-94 315.1 0.0 3.2e-94 314.9 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit CSTF2_hinge PF14327.1 KEY66866.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Cyt-b5 PF00173.23 KEY66867.1 - 3.2e-25 87.7 0.1 4.2e-25 87.3 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DSBA PF01323.15 KEY66869.1 - 2.2e-23 82.8 0.0 2.5e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain zf-H2C2_2 PF13465.1 KEY66870.1 - 3.6e-21 74.3 29.5 1.9e-07 31.0 1.2 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 KEY66870.1 - 1.5e-20 72.2 30.0 1.8e-05 24.7 0.1 5.1 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY66870.1 - 5.5e-14 51.3 27.8 0.00027 21.0 2.6 5.0 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KEY66870.1 - 3.9e-07 30.0 8.5 0.048 13.8 0.3 4.8 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEY66870.1 - 0.0028 17.8 11.7 2.8 8.2 0.0 4.5 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KEY66870.1 - 0.0036 17.1 15.6 1 9.3 0.9 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger C1_4 PF07975.7 KEY66870.1 - 0.09 12.7 3.7 3.9 7.5 0.0 2.8 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2HC_2 PF13913.1 KEY66870.1 - 0.34 10.6 7.6 0.9 9.2 0.2 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-TRAF PF02176.13 KEY66870.1 - 0.39 11.1 10.7 1 9.7 0.9 2.5 1 1 1 2 2 2 0 TRAF-type zinc finger Zn-ribbon_8 PF09723.5 KEY66870.1 - 1.3 9.0 11.5 18 5.3 0.1 3.8 2 1 1 3 3 3 0 Zinc ribbon domain C1_1 PF00130.17 KEY66870.1 - 3.6 7.3 7.9 0.56 9.9 1.7 2.3 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) VHS PF00790.14 KEY66871.1 - 8.3e-19 67.6 0.0 1.8e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 KEY66871.1 - 1.1e-10 41.4 1.3 2.3e-10 40.3 0.9 1.6 1 0 0 1 1 1 1 GAT domain Dymeclin PF09742.4 KEY66871.1 - 0.022 12.9 0.1 0.027 12.5 0.0 1.2 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein RAP1 PF07218.6 KEY66871.1 - 1.7 6.6 6.4 2.7 5.9 4.5 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PEMT PF04191.8 KEY66872.1 - 3.7e-30 104.1 4.3 3.7e-30 104.1 2.9 1.5 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.11 KEY66872.1 - 0.0084 15.8 0.3 0.016 14.9 0.1 1.6 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase RXT2_N PF08595.6 KEY66873.1 - 3.2e-34 117.8 0.0 1.5e-33 115.7 0.0 2.1 2 0 0 2 2 2 1 RXT2-like, N-terminal Glyco_hydro_3 PF00933.16 KEY66874.1 - 3.3e-71 239.7 0.0 4.2e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY66874.1 - 6.8e-56 189.3 0.0 1.2e-55 188.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEY66874.1 - 1.4e-20 72.9 0.3 1.4e-20 72.9 0.2 2.2 3 0 0 3 3 3 1 Fibronectin type III-like domain Sugar-bind PF04198.8 KEY66874.1 - 0.0098 14.8 0.0 0.019 13.8 0.0 1.4 1 0 0 1 1 1 1 Putative sugar-binding domain DUF1442 PF07279.6 KEY66874.1 - 0.075 12.1 1.4 0.25 10.4 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1442) CARDB PF07705.6 KEY66874.1 - 0.089 12.8 0.1 0.23 11.5 0.1 1.6 1 0 0 1 1 1 0 CARDB Glyco_hydro_31 PF01055.21 KEY66875.1 - 3.8e-112 375.3 1.5 4.6e-112 375.0 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KEY66875.1 - 4.2e-15 55.3 0.1 1.7e-14 53.4 0.0 2.2 1 0 0 1 1 1 1 Galactose mutarotase-like Glyco_hydro_3 PF00933.16 KEY66876.1 - 2.2e-54 184.4 0.0 3.1e-54 183.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY66876.1 - 5.1e-05 22.9 0.0 8.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.19 KEY66876.1 - 8.5e-05 22.5 0.0 0.00033 20.6 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Fe_hyd_SSU PF02256.12 KEY66876.1 - 0.014 15.3 0.0 0.73 9.8 0.0 2.5 2 0 0 2 2 2 0 Iron hydrogenase small subunit Acetyltransf_10 PF13673.1 KEY66876.1 - 0.015 15.4 0.0 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KEY66876.1 - 0.067 13.3 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Amidohydro_4 PF13147.1 KEY66877.1 - 6.8e-15 55.8 0.0 1.4e-07 31.8 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 KEY66877.1 - 1.5e-09 37.9 0.1 1.8e-08 34.4 0.1 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KEY66877.1 - 9.5e-09 34.9 0.0 4.6e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 KEY66877.1 - 3e-06 26.9 0.0 7.6e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase NDT80_PhoG PF05224.7 KEY66878.1 - 6.3e-33 114.3 0.0 9.3e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Glucosamine_iso PF01182.15 KEY66879.1 - 6.8e-27 94.4 0.0 1e-26 93.9 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hexokinase_2 PF03727.11 KEY66880.1 - 2.4e-31 108.8 0.0 1.2e-29 103.2 0.0 2.2 1 1 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KEY66880.1 - 2.8e-29 101.9 0.0 4.1e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase ChlI PF13541.1 KEY66880.1 - 0.11 12.0 0.0 0.54 9.7 0.0 2.1 1 1 0 1 1 1 0 Subunit ChlI of Mg-chelatase PTCB-BRCT PF12738.2 KEY66881.1 - 2.1e-30 104.3 0.5 2.4e-20 72.1 0.1 4.1 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 KEY66881.1 - 1.2e-29 102.2 0.1 1.4e-11 44.3 0.0 6.4 6 1 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain ESCRT-II PF05871.7 KEY66882.1 - 6.1e-45 152.5 0.0 8.6e-45 152.0 0.0 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit DUF2014 PF09427.5 KEY66883.1 - 2.4e-98 328.4 2.6 3.6e-98 327.8 1.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 KEY66883.1 - 1.5e-17 63.0 0.8 3.8e-17 61.7 0.5 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Vint PF14623.1 KEY66886.1 - 5.5e-47 159.2 0.0 8.3e-47 158.6 0.0 1.3 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.1 KEY66886.1 - 8.9e-29 99.4 0.0 1.9e-28 98.3 0.0 1.6 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.1 KEY66886.1 - 6.7e-20 71.8 0.0 1.1e-19 71.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KEY66886.1 - 5.5e-17 62.0 0.0 1.2e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KEY66886.1 - 2.5e-12 46.7 0.0 6.6e-10 38.8 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain Hint PF01079.15 KEY66886.1 - 0.018 14.2 0.0 0.042 13.0 0.0 1.5 1 0 0 1 1 1 0 Hint module VWA_CoxE PF05762.9 KEY66886.1 - 0.053 12.6 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein BNR PF02012.15 KEY66886.1 - 0.6 10.1 2.9 0.57 10.2 0.0 2.6 3 0 0 3 3 3 0 BNR/Asp-box repeat Thiolase_N PF00108.18 KEY66887.1 - 4.5e-72 242.2 1.0 6.1e-72 241.7 0.7 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KEY66887.1 - 1.9e-40 137.1 0.6 1.9e-40 137.1 0.4 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KEY66887.1 - 0.15 11.7 2.3 3.6 7.3 0.2 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Sigma54_AID PF00309.15 KEY66888.1 - 0.02 14.3 0.2 0.044 13.2 0.1 1.6 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) LRR_4 PF12799.2 KEY66889.1 - 1e-30 104.8 47.1 6.1e-07 28.9 1.9 10.3 4 4 5 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEY66889.1 - 2.7e-30 103.9 45.2 1.5e-06 27.8 3.8 8.0 3 2 1 7 7 7 5 Leucine rich repeat LRR_1 PF00560.28 KEY66889.1 - 6.8e-14 49.7 46.2 0.4 10.8 0.1 15.9 14 3 0 14 14 14 4 Leucine Rich Repeat LRR_7 PF13504.1 KEY66889.1 - 3.3e-08 32.4 37.4 2.8 8.5 0.0 13.3 15 0 0 15 15 15 4 Leucine rich repeat LRR_6 PF13516.1 KEY66889.1 - 3.5e-08 32.6 28.3 0.67 10.1 1.7 10.8 11 0 0 11 11 11 3 Leucine Rich repeat LRR_9 PF14580.1 KEY66889.1 - 0.0012 18.4 12.5 0.87 9.1 0.1 5.1 2 2 3 6 6 6 2 Leucine-rich repeat DUF2293 PF10056.4 KEY66890.1 - 3.8e-13 49.2 3.7 3.8e-13 49.2 2.6 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) DUF2360 PF10152.4 KEY66892.1 - 0.27 11.4 4.2 0.86 9.8 2.9 1.8 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) FA_hydroxylase PF04116.8 KEY66893.1 - 2.1e-16 60.3 13.8 2.1e-16 60.3 9.6 1.9 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF4013 PF13197.1 KEY66894.1 - 0.0031 16.8 3.4 0.0039 16.5 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4013) DUF307 PF03733.8 KEY66894.1 - 0.035 14.5 4.2 0.039 14.3 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF307) DUF2061 PF09834.4 KEY66894.1 - 0.31 11.2 6.9 9.3 6.5 2.8 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2061) MFS_1_like PF12832.2 KEY66895.1 - 0.15 11.8 5.4 0.85 9.4 0.1 3.1 2 1 1 3 3 3 0 MFS_1 like family DUF962 PF06127.6 KEY66895.1 - 1.5 8.7 6.0 1.6 8.6 0.9 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF962) Claudin_2 PF13903.1 KEY66895.1 - 3.3 7.3 18.8 0.023 14.3 5.7 2.4 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction 4HBT PF03061.17 KEY66896.1 - 6.9e-10 38.9 0.0 1.8e-08 34.4 0.0 2.3 2 0 0 2 2 2 1 Thioesterase superfamily DUF4442 PF14539.1 KEY66896.1 - 0.00017 21.5 0.0 0.00022 21.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) Peptidase_M28 PF04389.12 KEY66897.1 - 5.8e-24 84.7 0.3 1.4e-23 83.5 0.2 1.6 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KEY66897.1 - 1.3e-07 31.3 0.0 2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 KEY66897.1 - 5.2e-07 28.7 0.0 8.6e-07 28.0 0.0 1.3 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase fn3 PF00041.16 KEY66897.1 - 0.0012 18.9 0.9 0.0034 17.4 0.2 2.0 2 0 0 2 2 2 1 Fibronectin type III domain Fungal_trans PF04082.13 KEY66898.1 - 1.3e-11 43.8 1.3 2.3e-11 43.0 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY66898.1 - 2.6e-10 40.0 7.6 5.9e-10 38.8 5.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.9 KEY66899.1 - 1.4e-15 57.6 0.0 2.2e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY66899.1 - 3.3e-11 43.4 0.4 1.4e-07 31.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEY66899.1 - 3.5e-07 29.4 8.1 0.021 13.7 0.3 3.5 3 1 0 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEY66899.1 - 1.4e-05 25.3 0.0 0.0011 19.0 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEY66899.1 - 0.01 14.3 0.3 13 4.0 0.0 3.7 3 1 1 4 4 4 0 HI0933-like protein NAD_binding_9 PF13454.1 KEY66899.1 - 0.015 15.1 5.4 2.6 7.7 0.0 3.8 3 1 1 4 4 4 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KEY66899.1 - 0.032 13.0 2.2 0.13 11.1 0.0 2.8 3 1 1 4 4 4 0 FAD binding domain VPEP PF07589.6 KEY66899.1 - 1.1 9.2 4.2 0.67 9.9 0.5 2.5 2 0 0 2 2 2 0 PEP-CTERM motif Tfb2 PF03849.9 KEY66900.1 - 4.5e-132 440.1 0.0 5.7e-132 439.7 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 KEY66900.1 - 0.0007 19.3 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SinI PF08671.5 KEY66900.1 - 0.023 14.0 0.2 1.4 8.4 0.0 2.9 2 0 0 2 2 2 0 Anti-repressor SinI ABC2_membrane PF01061.19 KEY66902.1 - 2.3e-78 262.1 57.0 8.2e-42 142.7 14.4 2.6 3 0 0 3 3 2 2 ABC-2 type transporter NRDE PF05742.7 KEY66902.1 - 6.7e-38 130.5 0.0 7.6e-37 127.1 0.0 2.2 1 1 0 1 1 1 1 NRDE protein ABC_tran PF00005.22 KEY66902.1 - 3.3e-34 118.1 0.0 8.8e-16 58.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KEY66902.1 - 7.2e-31 105.9 0.0 4.7e-26 90.4 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter AAA_33 PF13671.1 KEY66902.1 - 3.6e-07 30.1 0.0 0.0012 18.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KEY66902.1 - 7e-06 26.8 0.0 0.0085 16.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KEY66902.1 - 2.6e-05 23.7 0.3 0.0078 15.6 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 KEY66902.1 - 2.6e-05 23.7 0.5 0.013 14.8 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.1 KEY66902.1 - 3.1e-05 24.1 0.0 0.045 13.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEY66902.1 - 6.1e-05 22.4 0.2 0.0058 16.1 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 KEY66902.1 - 7.7e-05 22.7 0.0 0.11 12.4 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KEY66902.1 - 0.00014 21.9 0.4 0.098 12.6 0.0 3.7 4 0 0 4 4 3 1 AAA ATPase domain DUF258 PF03193.11 KEY66902.1 - 0.00051 19.2 0.0 0.0033 16.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 UPF0079 PF02367.12 KEY66902.1 - 0.00054 19.5 0.5 0.74 9.4 0.1 2.6 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 ABC_trans_N PF14510.1 KEY66902.1 - 0.002 18.1 0.0 0.0068 16.4 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_18 PF13238.1 KEY66902.1 - 0.0027 18.0 0.0 0.087 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KEY66902.1 - 0.0032 17.6 0.0 0.31 11.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 KEY66902.1 - 0.0037 17.2 1.6 0.054 13.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 KEY66902.1 - 0.0052 16.4 0.4 4 7.0 0.1 2.8 3 0 0 3 3 2 1 NACHT domain SMC_N PF02463.14 KEY66902.1 - 0.02 14.1 0.0 0.49 9.5 0.0 2.8 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 KEY66902.1 - 0.025 14.3 0.4 12 5.6 0.1 2.8 2 0 0 2 2 2 0 Part of AAA domain ABC2_membrane_3 PF12698.2 KEY66902.1 - 0.034 13.1 45.3 0.0054 15.8 7.9 2.7 2 1 0 2 2 2 0 ABC-2 family transporter protein FtsK_SpoIIIE PF01580.13 KEY66902.1 - 0.045 13.2 0.1 2.2 7.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 KEY66902.1 - 0.053 13.7 0.0 4.5 7.4 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 KEY66902.1 - 0.054 13.9 0.0 8.3 6.9 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein PduV-EutP PF10662.4 KEY66902.1 - 0.1 12.0 1.0 3 7.3 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 KEY66902.1 - 0.11 11.8 0.1 5.4 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_24 PF13479.1 KEY66902.1 - 0.12 11.9 0.1 12 5.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KEY66902.1 - 2.5 8.3 5.5 0.86 9.8 0.0 3.0 4 0 0 4 4 3 0 AAA domain Methyltransf_16 PF10294.4 KEY66903.1 - 1.6e-23 83.0 0.0 3.2e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 KEY66903.1 - 0.0013 18.4 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY66903.1 - 0.0017 18.0 0.0 0.0034 17.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY66903.1 - 0.012 16.1 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KEY66903.1 - 0.013 16.0 0.1 0.035 14.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KEY66903.1 - 0.11 11.9 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain dCMP_cyt_deam_1 PF00383.17 KEY66904.1 - 3.1e-07 29.9 0.0 4.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Arginosuc_synth PF00764.14 KEY66907.1 - 1.7e-14 53.6 0.0 2.2e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Methyltransf_23 PF13489.1 KEY66909.1 - 3.7e-22 78.7 0.2 5.9e-22 78.0 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY66909.1 - 3e-13 50.0 0.0 5.4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY66909.1 - 3e-11 43.6 0.0 5.7e-10 39.5 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY66909.1 - 3.4e-11 42.9 0.0 5.2e-10 39.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY66909.1 - 6.1e-11 42.8 0.0 1.3e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY66909.1 - 1.7e-06 28.3 0.0 5.3e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY66909.1 - 5.6e-05 22.3 0.0 0.0004 19.5 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 KEY66909.1 - 0.00038 19.5 0.3 0.0041 16.2 0.0 2.5 3 0 0 3 3 3 1 Putative methyltransferase FtsJ PF01728.14 KEY66909.1 - 0.0026 17.7 0.0 0.0072 16.3 0.0 1.6 1 1 1 2 2 2 1 FtsJ-like methyltransferase MetW PF07021.7 KEY66909.1 - 0.0075 15.6 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 KEY66909.1 - 0.021 14.8 0.0 0.12 12.3 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 KEY66909.1 - 0.064 12.4 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase CMAS PF02353.15 KEY66909.1 - 0.093 11.7 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 KEY66909.1 - 0.16 11.3 0.0 0.31 10.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain AAA_16 PF13191.1 KEY66912.1 - 0.0032 17.4 0.0 0.0078 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Tcf25 PF04910.9 KEY66914.1 - 7.8e-69 232.3 0.1 7.8e-69 232.3 0.1 2.0 2 0 0 2 2 2 1 Transcriptional repressor TCF25 Apc3 PF12895.2 KEY66914.1 - 0.023 14.8 0.0 0.093 12.8 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Protocadherin PF08374.6 KEY66914.1 - 0.17 11.4 7.8 0.31 10.6 5.4 1.3 1 0 0 1 1 1 0 Protocadherin NST1 PF13945.1 KEY66914.1 - 4.3 7.3 13.3 0.31 11.1 5.5 1.9 2 0 0 2 2 2 0 Salt tolerance down-regulator LSM14 PF12701.2 KEY66915.1 - 1.4e-30 104.9 0.0 3.2e-30 103.8 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain V-SNARE PF05008.10 KEY66915.1 - 9.8e-22 76.9 1.1 2.3e-21 75.7 0.8 1.7 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus FDF PF09532.5 KEY66915.1 - 5.4e-19 68.6 1.3 1e-18 67.7 0.0 2.2 2 0 0 2 2 2 1 FDF domain V-SNARE_C PF12352.3 KEY66915.1 - 3.4e-18 65.4 2.6 3.4e-18 65.4 1.8 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus SM-ATX PF14438.1 KEY66915.1 - 0.00063 19.6 0.0 0.0017 18.2 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain Sec20 PF03908.8 KEY66915.1 - 0.14 11.8 0.3 0.39 10.4 0.2 1.7 1 0 0 1 1 1 0 Sec20 Amino_oxidase PF01593.19 KEY66916.1 - 5.4e-10 38.9 0.1 0.0067 15.5 0.0 3.2 3 0 0 3 3 3 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KEY66916.1 - 6.4e-10 38.9 0.5 1.5e-09 37.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEY66916.1 - 0.00021 20.3 0.0 0.00077 18.4 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEY66916.1 - 0.00068 19.5 0.0 0.0074 16.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEY66916.1 - 0.00075 19.3 0.0 0.46 10.2 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KEY66916.1 - 0.0015 18.6 0.0 0.039 14.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEY66916.1 - 0.0095 15.0 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Apo-VLDL-II PF05418.6 KEY66916.1 - 0.073 13.2 0.0 0.35 11.0 0.0 2.1 2 0 0 2 2 2 0 Apovitellenin I (Apo-VLDL-II) HI0933_like PF03486.9 KEY66916.1 - 0.12 10.8 0.0 0.35 9.2 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 KEY66916.1 - 0.18 10.6 0.2 0.25 10.1 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A CtaG_Cox11 PF04442.9 KEY66917.1 - 3.7e-55 185.8 0.0 5.7e-55 185.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 KOW PF00467.24 KEY66917.1 - 3.7e-07 29.6 2.4 8.1e-07 28.5 1.7 1.6 1 0 0 1 1 1 1 KOW motif DUF2990 PF11693.3 KEY66919.1 - 0.089 12.6 0.1 12 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) PARP PF00644.15 KEY66921.1 - 4e-11 42.7 0.1 9.5e-11 41.5 0.1 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 KEY66921.1 - 7.1e-07 28.7 0.0 1.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEY66921.1 - 0.0022 17.7 0.0 0.0077 15.9 0.0 1.8 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 KEY66921.1 - 0.052 13.4 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 RWD domain Pribosyl_synth PF14572.1 KEY66922.1 - 3.3e-30 105.1 0.2 3.7e-25 88.7 0.0 2.1 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KEY66922.1 - 8.2e-05 22.3 0.3 0.003 17.2 0.0 2.1 1 1 1 2 2 2 2 Phosphoribosyl transferase domain RNA_pol_Rpb4 PF03874.11 KEY66923.1 - 1.8e-24 86.0 0.0 2.1e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 FdhE PF04216.7 KEY66923.1 - 0.09 12.4 0.0 0.11 12.1 0.0 1.3 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation Glyco_transf_54 PF04666.8 KEY66923.1 - 0.15 10.7 0.0 0.25 10.0 0.0 1.3 2 0 0 2 2 2 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Ras PF00071.17 KEY66924.1 - 3.1e-15 55.9 0.0 1.9e-08 33.8 0.0 2.6 1 1 1 2 2 2 2 Ras family Miro PF08477.8 KEY66924.1 - 2.6e-06 27.9 0.0 4.1e-05 24.0 0.0 2.2 1 1 1 2 2 2 1 Miro-like protein Arf PF00025.16 KEY66924.1 - 0.0072 15.5 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family PseudoU_synth_1 PF01416.15 KEY66925.1 - 1.9e-27 95.7 0.0 1.7e-20 73.3 0.0 2.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase PIG-H PF10181.4 KEY66926.1 - 2e-27 94.5 0.2 3.4e-27 93.8 0.1 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component TEX13 PF15186.1 KEY66927.1 - 0.27 10.8 1.8 1.1 8.8 1.2 2.0 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family DUF2284 PF10050.4 KEY66929.1 - 2.2e-06 27.3 71.9 0.26 10.8 0.6 11.8 10 2 1 12 12 12 8 Predicted metal-binding protein (DUF2284) T2SI PF02501.12 KEY66929.1 - 0.0029 17.5 3.2 56 3.7 0.0 6.6 7 1 1 8 8 8 1 Type II secretion system (T2SS), protein I Toxin_16 PF07945.6 KEY66930.1 - 4.3 7.1 8.9 12 5.6 6.1 1.9 1 1 0 1 1 1 0 Janus-atracotoxin TMEM247 PF15444.1 KEY66931.1 - 0.00079 19.3 0.1 0.00088 19.1 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 247 Phage_Gp23 PF10669.4 KEY66931.1 - 0.21 11.6 4.5 0.36 10.9 3.1 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Snf7 PF03357.16 KEY66932.1 - 3.3e-20 72.1 6.5 3.3e-20 72.1 4.5 1.9 2 0 0 2 2 2 1 Snf7 GAS PF13851.1 KEY66932.1 - 0.0063 15.7 2.2 0.014 14.6 1.5 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Synapsin PF02078.11 KEY66932.1 - 0.041 13.9 0.6 0.093 12.8 0.3 1.6 1 1 0 1 1 1 0 Synapsin, N-terminal domain CS PF04969.11 KEY66933.1 - 2.1e-09 37.7 0.1 3.5e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 CS domain RRM_1 PF00076.17 KEY66934.1 - 4.7e-17 61.3 0.0 8.2e-17 60.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY66934.1 - 5e-12 45.6 0.0 7.9e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY66934.1 - 2.4e-05 24.1 0.0 4.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KEY66934.1 - 0.0029 17.9 3.3 0.0029 17.9 2.3 2.8 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Smg4_UPF3 PF03467.10 KEY66934.1 - 0.047 13.6 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 Smg-4/UPF3 family CENP-U PF13097.1 KEY66934.1 - 6.7 6.6 6.4 1.3 8.9 1.9 1.6 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit zf-CCCH PF00642.19 KEY66935.1 - 3.2e-06 26.6 0.7 3.2e-06 26.6 0.5 2.2 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NT-C2 PF10358.4 KEY66935.1 - 0.15 11.5 4.4 0.64 9.5 1.1 2.4 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins Metallophos PF00149.23 KEY66936.1 - 1.6e-05 24.3 2.1 4e-05 23.1 1.4 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEY66936.1 - 9.7e-05 22.2 0.0 0.00034 20.4 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mito_carr PF00153.22 KEY66938.1 - 4.5e-43 144.8 7.6 2.6e-16 59.0 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein AT_hook PF02178.14 KEY66939.1 - 0.11 12.1 23.9 0.069 12.8 1.8 3.7 3 0 0 3 3 3 0 AT hook motif Meth_synt_2 PF01717.13 KEY66940.1 - 1.9e-145 483.8 0.0 3.3e-139 463.3 0.0 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KEY66940.1 - 6.9e-125 416.4 0.0 7.1e-112 373.6 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Syntaxin_2 PF14523.1 KEY66942.1 - 0.065 13.2 5.5 0.13 12.2 3.8 1.5 1 0 0 1 1 1 0 Syntaxin-like protein DUF1690 PF07956.6 KEY66942.1 - 0.51 10.3 7.6 1.9 8.4 5.1 2.0 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) FlxA PF14282.1 KEY66942.1 - 0.86 9.5 17.4 82 3.2 11.1 2.9 2 1 0 2 2 2 0 FlxA-like protein GrpE PF01025.14 KEY66942.1 - 1.1 8.7 10.6 0.52 9.8 5.8 1.6 2 0 0 2 2 2 0 GrpE CBFD_NFYB_HMF PF00808.18 KEY66943.1 - 0.0042 17.0 0.2 0.0056 16.7 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.1 KEY66943.1 - 0.029 14.3 0.4 0.11 12.4 0.3 1.8 1 1 0 1 1 1 0 Centromere kinetochore component W Prefoldin_2 PF01920.15 KEY66944.1 - 1.7e-24 85.5 11.3 2.7e-24 84.9 7.8 1.3 1 0 0 1 1 1 1 Prefoldin subunit Ribosomal_L29 PF00831.18 KEY66944.1 - 0.5 10.1 7.7 0.22 11.2 0.3 2.5 2 0 0 2 2 2 0 Ribosomal L29 protein AAA_23 PF13476.1 KEY66944.1 - 0.54 10.5 10.6 0.65 10.2 7.4 1.1 1 0 0 1 1 1 0 AAA domain Prefoldin PF02996.12 KEY66944.1 - 0.73 9.5 8.7 0.25 10.9 0.9 2.3 1 1 1 2 2 2 0 Prefoldin subunit DUF148 PF02520.12 KEY66944.1 - 1.5 8.6 7.1 1.1 9.0 1.6 2.1 1 1 0 2 2 2 0 Domain of unknown function DUF148 Syntaxin-6_N PF09177.6 KEY66944.1 - 1.6 9.1 8.3 4.8 7.6 0.5 2.2 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Bap31 PF05529.7 KEY66944.1 - 2.2 7.6 8.8 2.9 7.3 0.1 2.1 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like eIF-4B PF06273.6 KEY66944.1 - 2.5 6.7 7.1 3 6.4 4.9 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Syntaxin PF00804.20 KEY66944.1 - 6 7.0 9.5 1.8e+02 2.3 6.4 2.3 1 1 0 1 1 1 0 Syntaxin FTA4 PF13093.1 KEY66944.1 - 6.9 6.0 11.0 11 5.4 7.6 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 MFS_1 PF07690.11 KEY66945.1 - 2.9e-38 131.5 44.4 2.9e-38 131.5 30.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY66945.1 - 5.4e-19 68.1 6.2 5.4e-19 68.1 4.3 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter HSP70 PF00012.15 KEY66946.1 - 4.6e-60 203.1 17.2 2e-54 184.5 3.1 2.7 1 1 1 2 2 2 2 Hsp70 protein FtsA PF14450.1 KEY66946.1 - 0.031 14.1 1.3 13 5.6 0.5 3.6 2 1 0 2 2 2 0 Cell division protein FtsA FGGY_C PF02782.11 KEY66946.1 - 0.07 12.7 0.0 0.23 11.0 0.0 1.9 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF148 PF02520.12 KEY66946.1 - 0.16 11.8 5.9 0.19 11.5 1.0 3.4 3 0 0 3 3 3 0 Domain of unknown function DUF148 H-kinase_dim PF02895.9 KEY66946.1 - 0.33 11.3 2.3 7.7 6.9 0.1 3.3 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain DUF3633 PF12315.3 KEY66946.1 - 1 8.6 7.9 16 4.7 2.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3633) Asp PF00026.18 KEY66947.1 - 1.8e-56 191.6 0.0 2.1e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEY66947.1 - 8.3e-07 29.0 0.0 5.1e-06 26.5 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KEY66947.1 - 3.4e-05 23.4 0.0 0.0001 21.8 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KEY66947.1 - 0.00049 20.5 0.1 0.12 12.9 0.0 3.1 2 1 0 2 2 2 1 Aspartyl protease CENP-Q PF13094.1 KEY66948.1 - 0.0093 15.9 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit PspA_IM30 PF04012.7 KEY66948.1 - 0.022 14.1 0.2 0.031 13.6 0.1 1.2 1 0 0 1 1 1 0 PspA/IM30 family TMF_TATA_bd PF12325.3 KEY66948.1 - 0.03 14.0 0.5 0.042 13.5 0.3 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Cluap1 PF10234.4 KEY66948.1 - 0.051 12.7 0.1 0.063 12.4 0.0 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Spc7 PF08317.6 KEY66948.1 - 0.057 12.0 0.1 0.073 11.7 0.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.3 KEY66948.1 - 0.072 12.9 0.3 0.1 12.5 0.2 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding SlyX PF04102.7 KEY66948.1 - 0.074 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 SlyX DUF4140 PF13600.1 KEY66948.1 - 0.081 13.3 0.2 0.14 12.5 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DASH_Spc34 PF08657.5 KEY66948.1 - 0.084 12.5 0.3 0.11 12.1 0.2 1.4 1 1 0 1 1 1 0 DASH complex subunit Spc34 V-SNARE PF05008.10 KEY66948.1 - 0.12 12.5 0.2 0.19 11.9 0.2 1.3 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus TMF_DNA_bd PF12329.3 KEY66948.1 - 0.15 11.8 1.3 0.26 11.1 0.9 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 KEY66948.1 - 0.76 9.5 3.7 0.17 11.7 0.4 1.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Fringe PF02434.11 KEY66949.1 - 0.00019 20.7 0.6 0.00071 18.8 0.3 2.0 1 1 0 1 1 1 1 Fringe-like Draxin PF15550.1 KEY66949.1 - 0.048 13.3 2.3 0.092 12.3 1.6 1.3 1 0 0 1 1 1 0 Draxin Thioredoxin PF00085.15 KEY66950.1 - 2.4e-11 43.2 0.0 2.4e-10 40.0 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.1 KEY66950.1 - 5.7e-09 36.0 0.0 0.012 15.3 0.0 3.1 3 0 0 3 3 3 3 Thioredoxin-like domain HyaE PF07449.6 KEY66950.1 - 0.0081 16.0 0.2 2 8.3 0.0 2.5 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE 2OG-FeII_Oxy PF03171.15 KEY66951.1 - 1.7e-05 25.0 0.0 4e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KEY66951.1 - 0.00036 20.9 0.1 0.00071 20.0 0.0 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily MIP PF00230.15 KEY66952.1 - 2.6e-46 157.9 18.1 3.4e-46 157.5 12.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein GDPD PF03009.12 KEY66954.1 - 6.5e-68 228.9 0.0 1.6e-67 227.6 0.0 1.7 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 KEY66954.1 - 6.3e-34 116.1 1.9 7.8e-15 54.9 0.9 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEY66954.1 - 6.9e-27 93.3 7.2 4.8e-09 36.5 0.1 5.5 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY66954.1 - 2.1e-26 91.3 5.4 7.2e-08 32.4 0.0 5.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 KEY66954.1 - 1.4e-25 87.7 13.6 2.2e-06 27.1 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat SPX PF03105.14 KEY66954.1 - 3.2e-22 79.6 4.0 3e-09 37.0 1.5 3.4 1 1 1 2 2 2 2 SPX domain Ank_3 PF13606.1 KEY66954.1 - 8.7e-19 65.7 7.1 0.00023 21.1 0.0 7.0 7 0 0 7 7 7 4 Ankyrin repeat UBA_4 PF14555.1 KEY66955.1 - 0.058 12.9 0.0 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain DUF866 PF05907.8 KEY66956.1 - 1.3e-46 158.0 0.1 1.4e-46 157.9 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF3716 PF12511.3 KEY66956.1 - 0.015 14.9 2.5 0.026 14.1 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Herpes_UL55 PF04537.7 KEY66956.1 - 0.032 13.6 0.0 0.041 13.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL55 protein PHD PF00628.24 KEY66956.1 - 0.07 12.8 0.6 0.17 11.5 0.4 1.7 1 0 0 1 1 1 0 PHD-finger Cas_CXXC_CXXC PF09706.5 KEY66956.1 - 0.83 9.8 3.6 1.3 9.2 1.7 1.9 1 1 2 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) zinc_ribbon_4 PF13717.1 KEY66956.1 - 1.9 8.2 4.9 4.2 7.1 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KEY66956.1 - 2 8.1 4.8 5.2 6.7 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 KEY66956.1 - 3.4 7.5 5.8 18 5.2 4.0 2.1 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Rpr2 PF04032.11 KEY66957.1 - 1.2e-07 31.5 0.0 2.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-nanos PF05741.8 KEY66957.1 - 0.19 11.6 1.4 2 8.4 0.0 2.6 3 0 0 3 3 3 0 Nanos RNA binding domain Cytochrome_C554 PF13435.1 KEY66957.1 - 0.9 9.5 3.6 2.6 8.1 0.6 2.1 2 0 0 2 2 2 0 Cytochrome c554 and c-prime zf-ZPR1 PF03367.8 KEY66958.1 - 2e-103 342.3 0.0 1.8e-52 176.7 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zinc-ribbons_6 PF07191.7 KEY66958.1 - 0.12 12.2 1.3 6.8 6.5 0.4 2.6 2 0 0 2 2 2 0 zinc-ribbons Elf1 PF05129.8 KEY66958.1 - 1.8 8.3 3.9 9.9 5.9 0.4 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like tRNA_int_end_N2 PF12928.2 KEY66960.1 - 4.6e-14 51.6 0.2 2.1e-13 49.4 0.1 2.0 2 0 0 2 2 2 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 KEY66960.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Arrestin_C PF02752.17 KEY66961.1 - 5.5e-17 62.1 0.0 7e-16 58.5 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.16 KEY66962.1 - 5.5e-43 146.8 0.0 6.5e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HSF_DNA-bind PF00447.12 KEY66963.1 - 5.9e-27 93.8 0.1 5.9e-27 93.8 0.1 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding Pro_isomerase PF00160.16 KEY66964.1 - 1.1e-41 142.6 0.1 2.9e-41 141.2 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.1 KEY66964.1 - 0.01 16.0 0.1 0.01 16.0 0.1 4.4 2 1 2 4 4 4 0 Domain of unknown function (DUF4604) Aldedh PF00171.17 KEY66965.1 - 2e-185 616.5 0.2 2.3e-185 616.3 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KEY66965.1 - 0.098 11.8 0.0 6.8 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Rgp1 PF08737.5 KEY66966.1 - 8e-118 394.1 0.0 3.5e-117 392.0 0.0 1.9 2 0 0 2 2 2 1 Rgp1 Laminin_G_3 PF13385.1 KEY66966.1 - 0.054 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Arrestin_N PF00339.24 KEY66966.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain WD40 PF00400.27 KEY66967.1 - 2.9e-13 49.1 18.8 3.2e-05 23.6 0.2 7.4 8 0 0 8 8 8 3 WD domain, G-beta repeat Bromodomain PF00439.20 KEY66967.1 - 1.8e-09 37.3 0.0 3.7e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain DUF4598 PF15370.1 KEY66967.1 - 0.08 13.2 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4598) PIGA PF08288.7 KEY66968.1 - 1.1e-47 160.2 2.8 1.7e-47 159.6 0.5 2.2 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 KEY66968.1 - 1.3e-30 106.0 0.0 1.9e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KEY66968.1 - 2.9e-16 59.8 0.0 5.3e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KEY66968.1 - 2.2e-15 56.8 0.5 3.9e-15 56.0 0.4 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 KEY66968.1 - 4.8e-14 52.8 0.0 7.3e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 KEY66968.1 - 1.7e-05 24.6 0.2 2.8e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 KEY66968.1 - 0.00026 21.2 0.0 0.00063 19.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 RestrictionSfiI PF11487.3 KEY66968.1 - 0.15 11.1 0.0 6.4 5.8 0.0 2.1 2 0 0 2 2 2 0 Type II restriction enzyme SfiI DEAD PF00270.24 KEY66969.1 - 1.5e-31 109.2 0.1 7.4e-16 58.0 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY66969.1 - 7e-21 73.8 0.0 1.4e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEY66969.1 - 7.8e-07 29.1 0.0 7.8e-07 29.1 0.0 3.1 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit zf-C2H2_2 PF12756.2 KEY66970.1 - 0.14 12.3 5.3 0.43 10.7 3.7 1.8 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KEY66970.1 - 0.66 10.4 10.2 4.2 7.9 1.3 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY66970.1 - 8.6 6.9 14.9 4.6 7.7 1.1 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type Fungal_trans PF04082.13 KEY66971.1 - 5.5e-14 51.6 2.0 9.4e-14 50.9 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY66971.1 - 1.9e-07 30.8 7.9 4.2e-07 29.7 5.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CFEM PF05730.6 KEY66972.1 - 1.7e-11 43.7 12.3 3e-11 42.9 8.5 1.4 1 0 0 1 1 1 1 CFEM domain DUF1634 PF07843.6 KEY66972.1 - 2.1 8.0 9.3 0.35 10.5 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) DUF2470 PF10615.4 KEY66973.1 - 6.3e-21 74.3 0.8 1e-20 73.7 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Helicase_C PF00271.26 KEY66974.1 - 4.2e-19 68.1 0.1 6e-16 58.0 0.0 2.7 2 1 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 KEY66974.1 - 3.7e-18 65.5 0.0 7.7e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SOG2 PF10428.4 KEY66975.1 - 1.2e-92 310.9 0.0 1.2e-92 310.9 0.0 2.4 3 0 0 3 3 3 1 RAM signalling pathway protein LRR_8 PF13855.1 KEY66975.1 - 3.7e-18 65.0 14.1 9e-09 34.9 1.7 3.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KEY66975.1 - 4.2e-17 61.3 11.0 4.4e-08 32.5 0.2 5.2 3 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEY66975.1 - 2.5e-09 35.8 11.5 0.19 11.8 0.0 6.1 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 KEY66975.1 - 6.8e-08 31.4 10.9 0.84 10.1 0.2 5.6 5 0 0 5 5 5 4 Leucine rich repeat LRR_6 PF13516.1 KEY66975.1 - 0.00014 21.5 3.3 4.9 7.5 0.0 4.9 4 0 0 4 4 4 2 Leucine Rich repeat DUF2464 PF10240.4 KEY66975.1 - 1.8 7.8 4.1 0.66 9.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2464) GCN5L1 PF06320.8 KEY66976.1 - 4.2e-06 26.5 0.6 6.3e-06 26.0 0.4 1.2 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Nop14 PF04147.7 KEY66976.1 - 8.2 4.2 8.0 9.8 3.9 5.6 1.1 1 0 0 1 1 1 0 Nop14-like family Steroid_dh PF02544.11 KEY66977.1 - 8.6e-31 106.7 0.5 1.4e-30 106.0 0.4 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KEY66977.1 - 0.0011 18.3 2.6 0.0012 18.2 0.9 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) ubiquitin PF00240.18 KEY66977.1 - 0.0036 16.6 0.1 0.0083 15.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family PEMT PF04191.8 KEY66977.1 - 0.0055 16.7 2.0 0.013 15.5 0.2 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase DWNN PF08783.6 KEY66977.1 - 0.1 12.5 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 DWNN domain TAT_ubiq PF07706.7 KEY66978.1 - 0.12 12.3 1.6 0.89 9.5 0.0 2.5 2 0 0 2 2 2 0 Aminotransferase ubiquitination site Ribosomal_S8e PF01201.17 KEY66979.1 - 6.2e-47 159.0 3.2 7.7e-47 158.7 2.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 KEY66979.1 - 0.16 12.2 3.0 0.63 10.3 2.1 2.0 1 1 0 1 1 1 0 Small acidic protein family RabGAP-TBC PF00566.13 KEY66980.1 - 1.8e-47 161.6 0.7 5e-46 156.8 0.5 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PilJ PF13675.1 KEY66980.1 - 0.036 14.3 6.4 2.9 8.2 1.1 3.1 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term CCDC155 PF14662.1 KEY66980.1 - 0.064 12.8 27.2 0.68 9.4 5.0 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 HALZ PF02183.13 KEY66980.1 - 0.35 10.6 15.5 0.98 9.1 0.4 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF1640 PF07798.6 KEY66980.1 - 7.1 6.6 16.5 1.7 8.6 8.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) DUF913 PF06025.7 KEY66981.1 - 1.4e-107 359.7 0.0 1.4e-107 359.7 0.0 4.5 6 0 0 6 6 6 1 Domain of Unknown Function (DUF913) HECT PF00632.20 KEY66981.1 - 3.5e-94 315.5 0.0 5.9e-94 314.7 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 KEY66981.1 - 8.5e-92 307.9 0.0 8.5e-92 307.9 0.0 3.1 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 KEY66981.1 - 1e-32 112.2 5.3 1e-32 112.2 3.6 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4414) Mut7-C PF01927.11 KEY66981.1 - 0.019 14.9 0.2 0.055 13.4 0.1 1.8 1 0 0 1 1 1 0 Mut7-C RNAse domain Trp_Tyr_perm PF03222.8 KEY66981.1 - 1.3 7.7 0.1 2.8 6.6 0.0 1.5 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family Ribosomal_S6e PF01092.14 KEY66982.1 - 9.4e-61 203.0 0.2 1.9e-60 202.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Ctf8 PF09696.5 KEY66983.1 - 9.6e-28 96.4 0.0 1.3e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Ctf8 Diphthamide_syn PF01866.12 KEY66984.1 - 3.6e-112 374.5 0.0 4.6e-112 374.2 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Aldose_epim PF01263.15 KEY66985.1 - 2.8e-44 151.4 0.0 3.9e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase ATP-synt_ab PF00006.20 KEY66986.1 - 3.8e-60 203.0 0.0 5.1e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KEY66986.1 - 3.8e-17 62.7 0.2 6.9e-17 61.9 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KEY66986.1 - 5e-12 45.8 1.1 1.1e-11 44.7 0.3 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KEY66986.1 - 0.00018 21.3 0.2 0.00042 20.1 0.1 1.6 1 0 0 1 1 1 1 HAS barrel domain Tubulin PF00091.20 KEY66987.1 - 1.4e-56 191.7 0.0 4.2e-56 190.1 0.0 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KEY66987.1 - 3.3e-48 162.8 0.1 7.5e-48 161.7 0.1 1.7 1 0 0 1 1 1 1 Tubulin C-terminal domain HMGL-like PF00682.14 KEY66987.1 - 1.2e-38 133.1 0.0 4.1e-38 131.3 0.0 1.8 1 1 0 1 1 1 1 HMGL-like Tubulin_3 PF14881.1 KEY66987.1 - 0.018 14.4 0.0 0.044 13.2 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain Pga1 PF10333.4 KEY66988.1 - 0.0021 17.7 0.2 0.0037 16.9 0.0 1.5 2 0 0 2 2 2 1 GPI-Mannosyltransferase II co-activator HAMP PF00672.20 KEY66988.1 - 0.15 12.2 0.4 0.29 11.3 0.3 1.5 1 0 0 1 1 1 0 HAMP domain WW PF00397.21 KEY66989.1 - 1.9e-06 27.6 0.0 3.7e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 WW domain Chitin_bind_3 PF03067.10 KEY66990.1 - 0.05 13.8 0.0 0.14 12.3 0.0 1.8 1 1 0 1 1 1 0 Chitin binding domain LsmAD PF06741.8 KEY66991.1 - 1.6e-20 72.9 1.6 1.6e-20 72.9 1.1 2.2 2 0 0 2 2 2 1 LsmAD domain Peptidase_M16 PF00675.15 KEY66992.1 - 9e-16 57.9 0.1 1.7e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KEY66992.1 - 4.3e-13 49.3 0.0 9.7e-13 48.1 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.8 KEY66993.1 - 1.4e-49 169.0 0.3 7.6e-48 163.2 0.1 2.6 2 1 1 3 3 3 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 KEY66993.1 - 1.3e-15 56.9 3.4 1.4e-12 47.2 0.3 3.7 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 KEY66993.1 - 1.7e-06 27.4 0.0 0.023 14.2 0.0 2.9 2 0 0 2 2 2 2 TFIIE alpha subunit TrmB PF01978.14 KEY66993.1 - 0.12 12.0 0.1 4 7.2 0.0 3.3 4 0 0 4 4 4 0 Sugar-specific transcriptional regulator TrmB Mito_carr PF00153.22 KEY66994.1 - 4.4e-29 100.0 1.0 1.1e-14 53.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DASH_Dad3 PF08656.5 KEY66995.1 - 2.8e-14 52.5 7.2 3.3e-14 52.3 0.0 5.1 6 0 0 6 6 6 1 DASH complex subunit Dad3 Imm47 PF15586.1 KEY66995.1 - 0.28 11.0 4.1 0.95 9.3 0.4 3.0 2 0 0 2 2 2 0 Immunity protein 47 Lip_prot_lig_C PF10437.4 KEY66995.1 - 0.51 10.0 7.5 4.3 7.0 0.3 5.1 3 1 1 5 5 5 0 Bacterial lipoate protein ligase C-terminus Ribosomal_S5_C PF03719.10 KEY66996.1 - 8.7e-16 56.9 0.0 1.7e-14 52.8 0.0 2.4 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KEY66996.1 - 5.2e-10 38.9 0.1 1.3e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain K-box PF01486.12 KEY66996.1 - 3.5 7.4 6.7 1.4 8.7 0.5 3.0 3 0 0 3 3 3 0 K-box region DUF1206 PF06724.6 KEY66997.1 - 0.066 12.9 0.3 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) PgaD PF13994.1 KEY66997.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.0 1 0 0 1 1 1 0 PgaD-like protein RasGEF PF00617.14 KEY66999.1 - 3.1e-45 154.2 0.2 4.8e-45 153.5 0.2 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KEY66999.1 - 1.6e-13 50.6 0.0 3.9e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 KEY66999.1 - 9.9e-13 48.6 0.0 2.5e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KEY66999.1 - 0.0048 16.2 0.0 0.034 13.5 0.0 2.2 1 1 0 1 1 1 1 Ras family AAA_22 PF13401.1 KEY66999.1 - 0.078 13.1 0.2 0.45 10.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KEY66999.1 - 0.23 12.2 2.1 1.9 9.3 0.1 3.2 3 2 0 3 3 3 0 AAA domain zf-HIT PF04438.11 KEY67001.1 - 8.4e-10 38.1 12.5 1.2e-09 37.6 8.7 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 KEY67001.1 - 3.5e-05 23.5 6.0 5.6e-05 22.9 4.2 1.3 1 0 0 1 1 1 1 MYND finger Nfu_N PF08712.6 KEY67002.1 - 6e-29 99.4 0.0 1.5e-28 98.2 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 KEY67002.1 - 2.6e-21 75.1 0.1 4.3e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain PSP1 PF04468.7 KEY67003.1 - 1.8e-31 107.9 0.9 3.6e-31 106.9 0.6 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Rotavirus_VP3 PF06929.6 KEY67003.1 - 0.34 8.7 0.4 0.48 8.2 0.3 1.1 1 0 0 1 1 1 0 Rotavirus VP3 protein TFIIF_alpha PF05793.7 KEY67004.1 - 0.028 12.8 3.2 0.034 12.5 2.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) mono-CXXC PF15626.1 KEY67004.1 - 0.1 12.5 0.3 0.22 11.4 0.2 1.6 1 0 0 1 1 1 0 single CXXC unit Ribosomal_L15e PF00827.12 KEY67005.1 - 4.2e-91 303.6 11.0 4.8e-91 303.4 7.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 Codanin-1_C PF15296.1 KEY67005.1 - 0.094 12.5 0.1 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 Codanin-1 C-terminus PUF PF00806.14 KEY67006.1 - 3.6e-57 186.7 15.3 5.1e-08 31.9 0.0 8.9 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat TylF PF05711.6 KEY67006.1 - 0.16 11.0 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) adh_short PF00106.20 KEY67007.1 - 2.2e-20 73.2 0.1 4.4e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY67007.1 - 2.2e-09 37.4 0.2 3.9e-09 36.6 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY67007.1 - 1.3e-08 34.7 0.0 2.6e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KEY67007.1 - 0.00057 19.9 1.2 0.0048 16.9 0.6 2.5 1 1 1 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KEY67007.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Trp_DMAT PF11991.3 KEY67008.1 - 3.2e-93 312.8 0.0 3.9e-93 312.5 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Peptidase_S9_N PF02897.10 KEY67008.1 - 0.058 11.9 0.0 0.086 11.3 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Tmemb_161AB PF10268.4 KEY67008.1 - 0.21 10.0 0.0 0.31 9.5 0.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB adh_short PF00106.20 KEY67010.1 - 7.3e-18 65.0 0.7 1.3e-17 64.2 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY67010.1 - 1.6e-12 47.4 0.5 2.7e-12 46.7 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY67010.1 - 0.0015 17.9 0.1 0.0025 17.3 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KEY67010.1 - 0.0098 15.6 0.1 0.029 14.1 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.12 KEY67010.1 - 0.027 13.3 0.1 0.044 12.6 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain p450 PF00067.17 KEY67011.1 - 2.5e-77 260.3 0.0 3.1e-77 260.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 KEY67012.1 - 2.4e-22 79.6 1.3 6.2e-22 78.2 0.9 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY67012.1 - 4.3e-22 79.0 0.0 2.1e-10 40.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY67012.1 - 1.3e-06 28.2 0.6 2e-06 27.6 0.4 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KEY67013.1 - 1.7e-22 80.1 0.0 2.3e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY67013.1 - 8e-15 55.2 0.0 1e-14 54.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEY67013.1 - 1.6e-06 27.7 0.1 2.8e-06 26.9 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KEY67013.1 - 1.8e-06 27.7 0.0 3.3e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 KEY67013.1 - 0.0031 17.0 0.2 0.0084 15.6 0.1 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.12 KEY67013.1 - 0.02 13.8 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain TrkA_N PF02254.13 KEY67013.1 - 0.038 13.9 0.1 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 KEY67013.1 - 0.062 12.7 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 KEY67013.1 - 0.064 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding ketoacyl-synt PF00109.21 KEY67014.1 - 2e-70 237.1 0.1 4.2e-70 236.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEY67014.1 - 3.2e-59 200.8 0.0 5.2e-59 200.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KEY67014.1 - 7.6e-52 176.3 0.0 1.3e-51 175.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 KEY67014.1 - 2.9e-45 154.1 0.2 1.4e-44 151.9 0.0 2.2 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KEY67014.1 - 1.7e-39 135.4 0.6 7.6e-39 133.2 0.1 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KEY67014.1 - 5e-39 132.8 0.4 1.8e-38 131.0 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KEY67014.1 - 1.2e-17 63.6 0.0 2.9e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY67014.1 - 1.4e-08 35.7 0.0 1e-07 32.8 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY67014.1 - 1.9e-07 30.7 0.1 4.8e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 KEY67014.1 - 0.0086 16.1 0.1 0.93 9.4 0.0 2.7 2 0 0 2 2 2 1 NADH(P)-binding PP-binding PF00550.20 KEY67014.1 - 0.062 13.5 0.1 0.26 11.6 0.0 2.0 2 0 0 2 2 2 0 Phosphopantetheine attachment site NMT1 PF09084.6 KEY67014.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 NMT1/THI5 like p450 PF00067.17 KEY67015.1 - 2.9e-66 223.9 0.0 3.4e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CotJA PF11007.3 KEY67015.1 - 0.17 11.5 0.5 3.2 7.4 0.0 2.9 3 0 0 3 3 3 0 Spore coat associated protein JA (CotJA) FAD_binding_4 PF01565.18 KEY67016.1 - 5.4e-22 77.7 0.8 1.1e-21 76.7 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY67016.1 - 0.0051 16.6 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like HAP1_N PF04849.8 KEY67017.1 - 0.067 12.1 0.1 0.071 12.0 0.0 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Glyco_hydro_61 PF03443.9 KEY67018.1 - 2.2e-20 73.3 0.0 2.6e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 p450 PF00067.17 KEY67019.1 - 1.4e-11 43.5 1.4 1.4e-10 40.3 0.9 2.2 1 1 0 1 1 1 1 Cytochrome P450 IBR PF01485.16 KEY67021.1 - 1.3e-12 47.4 39.7 7.5e-08 32.1 4.6 3.9 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 KEY67021.1 - 0.0025 17.5 7.0 0.0025 17.5 4.8 3.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEY67021.1 - 0.0029 17.6 6.5 0.0029 17.6 4.5 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEY67021.1 - 0.0031 17.1 4.3 0.0031 17.1 3.0 3.8 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEY67022.1 - 0.00012 22.0 4.2 0.00012 22.0 2.9 2.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KEY67022.1 - 0.00085 19.0 1.8 0.002 17.7 1.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 KEY67022.1 - 0.0011 18.8 6.8 0.0011 18.8 4.7 2.8 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KEY67022.1 - 0.0052 16.4 7.7 0.0052 16.4 5.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY67022.1 - 0.018 14.7 7.2 0.018 14.7 5.0 2.4 2 1 0 2 2 2 0 zinc-RING finger domain IBR PF01485.16 KEY67022.1 - 0.39 10.6 21.2 0.28 11.0 6.3 2.7 2 1 0 2 2 2 0 IBR domain Aldedh PF00171.17 KEY67023.1 - 4.6e-124 414.2 0.0 5.6e-124 413.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KEY67023.1 - 0.00021 20.1 0.0 0.00034 19.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF2961 PF11175.3 KEY67024.1 - 4.7e-87 291.2 4.5 6e-87 290.8 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2961) Fungal_trans PF04082.13 KEY67025.1 - 4.2e-10 38.9 0.4 6.6e-10 38.2 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_32N PF00251.15 KEY67026.1 - 5.6e-55 186.8 0.0 9.4e-55 186.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KEY67026.1 - 1.2e-08 35.2 0.0 2.8e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.1 KEY67026.1 - 0.00013 21.3 0.4 0.0029 16.9 0.3 2.0 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 KEY67026.1 - 0.11 12.3 3.4 1.1 9.3 0.1 3.4 3 0 0 3 3 3 0 BNR/Asp-box repeat Sugar_tr PF00083.19 KEY67027.1 - 1.2e-61 208.6 24.0 1.6e-61 208.2 16.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY67027.1 - 2.2e-12 46.3 28.6 2.2e-12 46.3 19.8 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily HET PF06985.6 KEY67028.1 - 5.1e-10 39.6 0.1 1.1e-09 38.5 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.2 KEY67029.1 - 9.2e-22 78.0 0.0 1.1e-21 77.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY67029.1 - 2e-08 34.1 0.1 2.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 KEY67029.1 - 0.075 11.6 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S28 PF05577.7 KEY67030.1 - 6.3e-47 160.1 0.1 1.5e-45 155.5 0.1 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 FAD_binding_3 PF01494.14 KEY67031.1 - 2.7e-27 95.7 0.0 9.5e-16 57.7 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KEY67031.1 - 1.9e-08 33.6 0.0 1.9e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY67031.1 - 1.8e-07 31.0 0.0 5.1e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KEY67031.1 - 3.8e-07 29.5 1.7 0.002 17.2 0.1 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 KEY67031.1 - 2.1e-06 28.0 0.2 8.8e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY67031.1 - 0.00012 21.1 0.6 0.2 10.5 0.1 2.8 3 1 0 3 3 3 2 Lycopene cyclase protein Thi4 PF01946.12 KEY67031.1 - 0.00021 20.4 0.2 0.00038 19.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KEY67031.1 - 0.00026 20.9 0.0 0.00046 20.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KEY67031.1 - 0.00036 19.2 0.1 0.0015 17.2 0.1 1.9 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.9 KEY67031.1 - 0.00087 17.8 0.1 0.0018 16.8 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KEY67031.1 - 0.0015 17.4 1.0 0.0019 17.1 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 KEY67031.1 - 0.0016 18.0 0.3 0.0085 15.6 0.1 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 KEY67031.1 - 0.0017 17.5 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEY67031.1 - 0.0021 18.1 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KEY67031.1 - 0.004 16.6 0.0 0.016 14.6 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 KEY67031.1 - 0.004 16.0 0.0 0.0083 15.0 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_7 PF13241.1 KEY67031.1 - 0.0079 16.4 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.13 KEY67031.1 - 0.049 13.6 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 KEY67031.1 - 0.08 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.5 KEY67031.1 - 0.085 11.6 0.0 0.27 10.0 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase DOPA_dioxygen PF08883.6 KEY67032.1 - 2e-30 104.9 0.0 2.7e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Fasciclin PF02469.17 KEY67033.1 - 2.3e-46 156.9 0.5 3.6e-26 91.6 0.1 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF2796 PF10986.3 KEY67035.1 - 0.0069 16.3 0.2 0.014 15.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2796) Sigma70_ner PF04546.8 KEY67035.1 - 4.1 6.9 5.7 0.37 10.3 0.4 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region UPRTase PF14681.1 KEY67036.1 - 9.1e-66 221.0 0.0 1.1e-65 220.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KEY67036.1 - 1.3e-06 28.1 0.0 2.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Aldedh PF00171.17 KEY67037.1 - 1.2e-130 436.0 0.0 1.3e-130 435.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KEY67037.1 - 0.16 10.6 0.0 0.25 10.0 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) UPRTase PF14681.1 KEY67038.1 - 2.2e-47 160.9 0.0 2.2e-44 151.1 0.0 2.0 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KEY67038.1 - 2.6e-11 43.3 0.1 3.5e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UQ_con PF00179.21 KEY67038.1 - 0.1 12.0 0.0 2.6 7.4 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin-conjugating enzyme DUF1688 PF07958.6 KEY67039.1 - 4.4e-158 526.2 0.0 5e-158 526.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) DUF2419 PF10343.4 KEY67039.1 - 0.018 14.3 0.0 4.3 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2419) GTP_CH_N PF12471.3 KEY67040.1 - 1.1e-87 292.7 0.0 1.4e-87 292.3 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 KEY67040.1 - 8.6e-17 60.8 0.0 1.3e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Bradykinin PF06753.7 KEY67042.1 - 0.013 14.9 0.5 0.029 13.8 0.3 1.5 1 0 0 1 1 1 0 Bradykinin ABC2_membrane PF01061.19 KEY67043.1 - 2.4e-96 320.9 35.7 5e-51 172.8 8.9 2.2 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 KEY67043.1 - 1.6e-39 135.3 0.0 2.2e-18 66.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KEY67043.1 - 2.7e-30 104.0 0.0 9e-26 89.5 0.0 2.6 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 KEY67043.1 - 1.1e-14 54.3 23.1 1e-09 37.8 6.4 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KEY67043.1 - 1e-07 31.5 0.0 0.0003 20.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEY67043.1 - 1.7e-05 24.8 0.2 0.0045 16.9 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KEY67043.1 - 5.4e-05 22.4 0.0 0.0023 17.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 KEY67043.1 - 7.2e-05 22.7 0.6 0.1 12.5 0.4 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KEY67043.1 - 9.4e-05 22.5 0.0 0.044 13.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KEY67043.1 - 0.00044 20.3 0.0 0.25 11.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KEY67043.1 - 0.0007 19.0 0.3 0.05 13.1 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KEY67043.1 - 0.00083 19.6 0.0 0.91 9.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KEY67043.1 - 0.00087 19.1 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 KEY67043.1 - 0.00094 18.6 0.3 0.69 9.3 0.2 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KEY67043.1 - 0.0024 18.6 0.0 0.71 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEY67043.1 - 0.0027 17.4 1.0 1.4 8.7 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain PduV-EutP PF10662.4 KEY67043.1 - 0.027 13.9 0.4 1.4 8.4 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 KEY67043.1 - 0.027 14.1 0.0 3.8 7.1 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 KEY67043.1 - 0.028 14.0 0.8 2.2 7.8 0.2 2.4 2 0 0 2 2 2 0 NACHT domain DUF357 PF04010.8 KEY67043.1 - 0.071 12.8 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF357) MobB PF03205.9 KEY67043.1 - 0.091 12.4 0.0 9.7 5.8 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KEY67043.1 - 0.12 12.3 0.0 17 5.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase T2SE PF00437.15 KEY67043.1 - 0.13 11.1 0.0 3.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 KEY67043.1 - 0.19 11.1 0.1 15 4.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC2_membrane_2 PF12679.2 KEY67043.1 - 0.37 9.5 11.8 0.38 9.5 2.8 2.5 2 0 0 2 2 2 0 ABC-2 family transporter protein FA_desaturase PF00487.19 KEY67044.1 - 7.6e-28 97.6 13.4 1.2e-27 97.0 9.3 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KEY67044.1 - 6.2e-09 35.9 0.0 1.3e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) RabGAP-TBC PF00566.13 KEY67045.1 - 3.4e-33 114.9 0.0 5.1e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MAP1B_neuraxin PF00414.12 KEY67045.1 - 0.5 9.7 2.4 1.3 8.5 1.7 1.7 1 0 0 1 1 1 0 Neuraxin and MAP1B repeat HET PF06985.6 KEY67046.1 - 1.2e-33 116.2 0.0 1.8e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cpn60_TCP1 PF00118.19 KEY67048.1 - 1.1e-132 443.1 9.8 1.3e-132 442.8 6.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GARS_C PF02843.11 KEY67048.1 - 0.12 12.5 0.7 0.41 10.8 0.1 2.2 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain eIF2A PF08662.6 KEY67049.1 - 5.3e-43 147.0 1.9 1.2e-39 136.0 0.2 4.4 4 1 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_5 PF13893.1 KEY67049.1 - 1.2e-05 25.0 0.0 2.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KEY67049.1 - 0.00037 20.2 0.2 1.7 8.6 0.0 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat RRM_1 PF00076.17 KEY67049.1 - 0.00047 19.7 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY67049.1 - 0.00071 19.5 0.0 0.0018 18.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribonuc_2-5A PF06479.7 KEY67050.1 - 1.1e-43 148.1 0.0 2e-43 147.3 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 KEY67050.1 - 3.6e-35 121.3 0.0 5.5e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY67050.1 - 5.7e-15 55.0 0.0 2e-14 53.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 KEY67050.1 - 5.2e-06 25.7 0.0 5.9e-05 22.3 0.0 2.7 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_2 PF13360.1 KEY67050.1 - 0.00091 18.7 0.0 0.0071 15.8 0.0 2.4 1 1 0 1 1 1 1 PQQ-like domain Kdo PF06293.9 KEY67050.1 - 0.0018 17.3 0.0 0.0038 16.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KEY67050.1 - 0.077 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL zf-C3HC4_3 PF13920.1 KEY67051.1 - 2.3e-05 23.9 7.3 2.3e-05 23.9 5.0 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) SWIB PF02201.13 KEY67052.1 - 1.6e-26 91.7 0.5 6.5e-26 89.8 0.2 2.0 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 KEY67052.1 - 2.5e-14 52.7 1.6 4.5e-14 51.9 0.7 1.8 2 0 0 2 2 2 1 DEK C terminal domain CAF-1_p150 PF11600.3 KEY67052.1 - 0.062 12.6 8.1 0.1 11.9 5.6 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SOBP PF15279.1 KEY67052.1 - 0.45 10.8 3.8 0.52 10.6 2.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SRP-alpha_N PF04086.8 KEY67052.1 - 5.5 6.2 12.6 7.4 5.8 8.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Exo_endo_phos PF03372.18 KEY67054.1 - 1.2e-05 25.3 0.3 1.5e-05 25.0 0.2 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Mur_ligase_C PF02875.16 KEY67054.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain SLT_2 PF13406.1 KEY67058.1 - 0.013 14.4 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Transglycosylase SLT domain SLT PF01464.15 KEY67058.1 - 0.07 12.6 0.1 0.33 10.4 0.1 2.1 1 1 0 1 1 1 0 Transglycosylase SLT domain Peptidase_C30 PF05409.8 KEY67058.1 - 0.091 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Coronavirus endopeptidase C30 F-box-like PF12937.2 KEY67059.1 - 0.025 14.2 0.0 0.07 12.8 0.0 1.8 1 0 0 1 1 1 0 F-box-like DUF3712 PF12505.3 KEY67061.1 - 1.8e-21 76.4 0.0 4.3e-21 75.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) Adaptin_N PF01602.15 KEY67062.1 - 0.00016 20.1 1.1 5.1 5.2 0.3 5.6 3 2 2 6 6 6 2 Adaptin N terminal region DUF3571 PF12095.3 KEY67062.1 - 0.0029 17.8 8.3 8.4 6.7 0.0 5.3 2 1 2 4 4 4 1 Protein of unknown function (DUF3571) DHC_N1 PF08385.7 KEY67062.1 - 0.028 12.8 0.1 7.4 4.8 0.0 4.0 3 1 1 4 4 4 0 Dynein heavy chain, N-terminal region 1 Ret_tiss PF10044.4 KEY67062.1 - 0.037 14.5 0.0 48 4.5 0.0 5.1 5 2 2 7 7 7 0 Retinal tissue protein FlgN PF05130.7 KEY67062.1 - 9.5 6.4 41.6 0.36 11.0 1.8 8.0 3 2 4 8 8 8 0 FlgN protein HET PF06985.6 KEY67063.1 - 4.3e-29 101.4 0.0 7.9e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Erp_C PF06780.6 KEY67064.1 - 0.042 13.6 0.1 0.052 13.3 0.1 1.1 1 0 0 1 1 1 0 Erp protein C-terminus Plant_tran PF04827.9 KEY67064.1 - 0.11 11.8 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Plant transposon protein NUDIX PF00293.23 KEY67066.1 - 3e-22 78.7 0.3 3.9e-22 78.3 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 KEY67066.1 - 0.002 17.4 0.1 0.0038 16.6 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain SseB PF07179.7 KEY67066.1 - 0.017 14.9 0.5 5.1 6.9 0.0 2.4 2 1 0 2 2 2 0 SseB protein N-terminal domain DUF3445 PF11927.3 KEY67067.1 - 3e-69 233.1 0.0 3.6e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) NolX PF05819.6 KEY67067.1 - 0.029 12.7 0.0 0.04 12.2 0.0 1.2 1 0 0 1 1 1 0 NolX protein p450 PF00067.17 KEY67068.1 - 9.1e-35 120.0 0.0 1.5e-31 109.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF3969 PF13108.1 KEY67068.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3969) Peptidase_C97 PF05903.9 KEY67069.1 - 1e-06 28.6 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4105 PF13387.1 KEY67069.1 - 0.0043 16.2 0.0 0.0058 15.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4105) LRAT PF04970.8 KEY67069.1 - 0.006 16.5 0.4 0.12 12.3 0.0 2.2 1 1 0 2 2 2 1 Lecithin retinol acyltransferase AIM24 PF01987.12 KEY67070.1 - 1.1e-49 168.8 0.0 1.3e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Methyltransf_32 PF13679.1 KEY67071.1 - 6.8e-22 77.6 0.2 1.1e-21 76.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY67071.1 - 2.7e-05 23.7 0.0 5.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY67071.1 - 6.8e-05 23.4 0.0 0.00014 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY67071.1 - 0.00024 20.5 0.0 0.00052 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KEY67071.1 - 0.0087 15.1 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KEY67071.1 - 0.013 15.2 0.0 0.072 12.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 KEY67071.1 - 0.02 15.3 0.0 0.066 13.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 KEY67071.1 - 0.021 13.9 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_2 PF00891.13 KEY67071.1 - 0.099 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase PNP_UDP_1 PF01048.15 KEY67072.1 - 3.6e-05 22.8 0.0 0.00083 18.3 0.0 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily NUDIX PF00293.23 KEY67073.1 - 3e-18 65.7 0.1 3.8e-18 65.4 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 KEY67073.1 - 0.00073 18.9 0.1 0.001 18.4 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain Pec_lyase_C PF00544.14 KEY67075.1 - 3.5e-49 166.9 5.3 4.9e-49 166.5 3.7 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KEY67075.1 - 8.7e-07 28.8 15.7 2.7e-06 27.2 8.6 2.1 1 1 1 2 2 2 2 Right handed beta helix region Chitin_bind_3 PF03067.10 KEY67076.1 - 1.4e-07 31.9 0.1 1.7e-07 31.6 0.1 1.3 1 1 0 1 1 1 1 Chitin binding domain zf-AN1 PF01428.11 KEY67077.1 - 1.1e-10 41.2 11.4 1.5e-10 40.7 7.9 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger Hydantoinase_B PF02538.9 KEY67078.1 - 9.2e-197 654.4 0.0 4.3e-195 648.9 0.0 2.1 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KEY67078.1 - 2.4e-96 322.2 0.5 5e-96 321.2 0.3 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KEY67078.1 - 6.8e-61 204.8 1.3 3.1e-59 199.4 0.1 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region NmrA PF05368.8 KEY67079.1 - 1.2e-08 34.4 0.0 1.4e-07 31.0 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY67079.1 - 0.00012 22.1 0.1 0.00047 20.2 0.1 2.2 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEY67079.1 - 0.023 13.4 0.1 0.039 12.6 0.1 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family A_deaminase PF00962.17 KEY67080.1 - 2.1e-42 145.2 0.0 1.6e-41 142.3 0.0 2.0 1 1 0 1 1 1 1 Adenosine/AMP deaminase Acyl-CoA_dh_1 PF00441.19 KEY67081.1 - 3.4e-14 53.2 0.3 3.2e-13 50.0 0.2 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KEY67081.1 - 1.9e-08 33.6 0.1 5.3e-08 32.2 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KEY67081.1 - 5.3e-05 23.4 0.2 0.096 12.9 0.0 2.8 3 0 0 3 3 3 2 Acyl-CoA dehydrogenase, C-terminal domain Excalibur PF05901.6 KEY67082.1 - 5.5 7.4 8.2 1e+02 3.3 0.1 4.1 4 0 0 4 4 4 0 Excalibur calcium-binding domain APG5 PF04106.7 KEY67083.1 - 3.6e-44 150.5 0.0 9.8e-44 149.1 0.0 1.7 1 1 0 1 1 1 1 Autophagy protein Apg5 WD40 PF00400.27 KEY67084.1 - 4.3e-33 111.9 7.0 1.1e-07 31.4 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KEY67084.1 - 2.3e-05 23.3 0.2 0.53 8.9 0.0 3.5 2 1 0 4 4 4 2 Nup133 N terminal like PQQ_2 PF13360.1 KEY67084.1 - 4e-05 23.2 0.5 0.07 12.5 0.1 2.4 2 0 0 2 2 2 2 PQQ-like domain eIF2A PF08662.6 KEY67084.1 - 0.00042 20.0 0.0 0.069 12.8 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KEY67084.1 - 0.0017 16.5 2.0 1.6 6.7 0.1 3.1 1 1 2 3 3 3 2 Nucleoporin Nup120/160 TSNR_N PF04705.7 KEY67084.1 - 0.094 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Thiostrepton-resistance methylase, N terminus PQQ_3 PF13570.1 KEY67084.1 - 0.21 11.8 7.5 2.9 8.2 0.0 4.5 5 1 0 5 5 5 0 PQQ-like domain UAF_Rrn10 PF05234.6 KEY67085.1 - 0.0062 16.5 0.0 0.0098 15.9 0.0 1.3 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Zn_clus PF00172.13 KEY67087.1 - 2.6e-08 33.6 13.7 4e-08 33.0 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3919 PF13057.1 KEY67087.1 - 0.48 9.8 0.0 0.79 9.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) InaF-motif PF15018.1 KEY67089.1 - 0.094 12.1 0.1 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 TRP-interacting helix FAD_binding_4 PF01565.18 KEY67090.1 - 1.3e-21 76.4 3.0 2.4e-21 75.6 2.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY67090.1 - 1.5e-10 40.7 0.0 2.8e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Abhydrolase_6 PF12697.2 KEY67091.1 - 3.4e-36 125.2 2.1 4.1e-36 124.9 1.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY67091.1 - 2.1e-16 60.1 0.2 6.8e-16 58.5 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY67091.1 - 6.8e-16 58.3 0.4 9.7e-16 57.8 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KEY67091.1 - 3e-10 39.7 0.0 6.3e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 KEY67091.1 - 2.5e-06 26.5 0.0 4.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Thioesterase PF00975.15 KEY67091.1 - 6e-06 26.6 0.1 1.2e-05 25.6 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain DUF1057 PF06342.7 KEY67091.1 - 5.1e-05 22.2 0.0 7.1e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) DLH PF01738.13 KEY67091.1 - 0.00032 20.0 0.3 0.0017 17.7 0.0 2.2 2 2 0 2 2 2 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.2 KEY67091.1 - 0.0015 17.4 0.1 0.0037 16.1 0.1 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme PGAP1 PF07819.8 KEY67091.1 - 0.0049 16.4 0.5 0.011 15.3 0.4 1.5 1 1 0 1 1 1 1 PGAP1-like protein Peptidase_S9 PF00326.16 KEY67091.1 - 0.0059 15.8 0.0 2.9 7.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ndr PF03096.9 KEY67091.1 - 0.018 13.5 0.0 0.49 8.8 0.0 2.0 2 0 0 2 2 2 0 Ndr family Ferric_reduct PF01794.14 KEY67092.1 - 7.3e-18 64.8 20.2 2.3e-17 63.2 14.0 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KEY67092.1 - 7.9e-05 22.6 0.1 0.076 12.9 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KEY67092.1 - 0.0051 16.6 0.1 0.078 12.8 0.1 2.4 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KEY67092.1 - 0.023 15.2 0.2 0.13 12.8 0.1 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain CFEM PF05730.6 KEY67093.1 - 0.0028 17.4 3.8 0.0028 17.4 2.6 2.0 2 1 0 2 2 2 1 CFEM domain Zip PF02535.17 KEY67093.1 - 0.18 10.7 1.5 0.25 10.3 1.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2796 PF10986.3 KEY67093.1 - 1 9.2 10.2 1.6 8.6 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) MFS_1 PF07690.11 KEY67094.1 - 8.5e-28 97.0 57.4 1.9e-25 89.3 31.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KEY67095.1 - 4.2e-39 134.2 32.7 4.2e-39 134.2 22.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KEY67095.1 - 5.3e-07 28.2 3.3 9.5e-07 27.3 2.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.11 KEY67095.1 - 0.00015 20.6 3.7 0.00027 19.7 2.5 1.4 1 0 0 1 1 1 1 BT1 family DUF4545 PF15078.1 KEY67095.1 - 0.021 13.7 0.0 0.03 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4545) Ferritin_2 PF13668.1 KEY67096.1 - 2.8e-13 49.9 0.1 4.5e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain ABC2_membrane PF01061.19 KEY67097.1 - 2.7e-72 242.3 54.1 1.3e-39 135.5 17.5 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 KEY67097.1 - 7.9e-35 120.1 0.0 5.1e-17 62.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KEY67097.1 - 1.6e-21 75.9 0.3 7.7e-20 70.4 0.0 2.9 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 KEY67097.1 - 4.2e-13 49.0 37.9 2.1e-09 36.8 6.2 3.2 3 0 0 3 3 3 2 ABC-2 family transporter protein DUF258 PF03193.11 KEY67097.1 - 7.4e-06 25.2 0.2 0.00013 21.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KEY67097.1 - 1.1e-05 24.8 1.4 0.005 16.3 0.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KEY67097.1 - 3.1e-05 23.4 1.0 0.0027 17.1 0.3 3.0 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 KEY67097.1 - 6.1e-05 22.5 0.2 0.012 15.0 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family SMC_N PF02463.14 KEY67097.1 - 0.00016 20.9 1.6 0.0052 16.0 0.0 2.5 3 0 0 3 3 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KEY67097.1 - 0.00051 20.1 0.2 0.31 11.2 0.1 3.4 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KEY67097.1 - 0.00055 19.9 0.7 0.064 13.2 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 KEY67097.1 - 0.00088 19.3 0.2 0.55 10.1 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 KEY67097.1 - 0.03 14.2 0.9 0.76 9.6 0.3 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KEY67097.1 - 0.033 14.5 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KEY67097.1 - 0.033 13.6 3.9 1 8.7 0.4 2.6 2 1 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 KEY67097.1 - 0.037 13.9 0.3 0.38 10.7 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase ArgK PF03308.11 KEY67097.1 - 0.075 11.8 0.4 0.54 8.9 0.1 2.0 2 0 0 2 2 2 0 ArgK protein UPF0079 PF02367.12 KEY67097.1 - 0.37 10.4 1.2 4.5 6.9 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF87 PF01935.12 KEY67097.1 - 0.45 10.2 1.4 1.4 8.7 1.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_30 PF13604.1 KEY67097.1 - 0.53 9.8 2.4 1.3 8.5 0.2 2.6 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 KEY67097.1 - 1.3 8.6 3.7 6.6 6.3 0.6 2.5 2 0 0 2 2 2 0 NACHT domain DUF427 PF04248.7 KEY67098.1 - 8.9e-37 124.6 0.1 1.9e-28 97.9 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) NACHT PF05729.7 KEY67099.1 - 8e-11 41.8 0.1 6.7e-10 38.8 0.0 2.5 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KEY67099.1 - 4.4e-05 23.5 0.4 0.0011 19.0 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 KEY67099.1 - 0.0013 18.8 0.1 0.0041 17.2 0.1 1.9 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 KEY67099.1 - 0.0015 18.6 0.0 0.0067 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KEY67099.1 - 0.0019 17.6 0.2 0.0052 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 KEY67099.1 - 0.0035 17.6 0.0 0.0092 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEY67099.1 - 0.0052 17.6 0.0 0.026 15.3 0.0 2.4 2 1 0 2 2 1 1 AAA domain CITED PF04487.7 KEY67099.1 - 0.014 15.6 1.9 0.019 15.1 0.8 1.5 1 1 0 1 1 1 0 CITED AAA_25 PF13481.1 KEY67099.1 - 0.03 13.7 0.0 0.18 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KEY67099.1 - 0.033 13.3 0.0 0.11 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 KEY67099.1 - 0.047 13.9 0.2 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 KEY67099.1 - 0.05 13.4 0.0 0.19 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KEY67099.1 - 0.091 12.9 0.1 0.91 9.7 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KEY67099.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.9 KEY67099.1 - 0.14 11.1 7.9 0.49 9.3 1.8 3.0 2 1 0 2 2 2 0 KAP family P-loop domain PhyH PF05721.8 KEY67100.1 - 7.4e-23 81.6 0.1 1.4e-22 80.7 0.1 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) CMAS PF02353.15 KEY67101.1 - 6.5e-72 241.8 0.0 1.2e-71 241.0 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 KEY67101.1 - 4.2e-14 52.7 0.0 8.7e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY67101.1 - 7.6e-14 52.2 0.0 1.6e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY67101.1 - 2.6e-13 49.9 0.0 1.1e-12 48.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY67101.1 - 5.9e-10 39.4 0.0 1.3e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY67101.1 - 8.1e-10 38.4 0.0 1.4e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY67101.1 - 2.7e-09 37.3 0.0 7.5e-09 35.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY67101.1 - 9.5e-07 28.1 0.0 1.4e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KEY67101.1 - 1e-06 28.7 0.0 1.9e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY67101.1 - 7.3e-06 25.4 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KEY67101.1 - 0.00035 20.1 0.0 0.00053 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 KEY67101.1 - 0.002 17.4 0.0 0.0038 16.5 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 RrnaAD PF00398.15 KEY67101.1 - 0.0035 16.4 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Cons_hypoth95 PF03602.10 KEY67101.1 - 0.0046 16.3 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_32 PF13679.1 KEY67101.1 - 0.017 14.7 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KEY67101.1 - 0.067 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.12 KEY67101.1 - 0.16 11.0 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase UTP15_C PF09384.5 KEY67102.1 - 3.2e-41 140.4 0.0 5.1e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 KEY67102.1 - 1.2e-27 94.7 4.2 3.7e-10 39.2 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat C2 PF00168.25 KEY67103.1 - 1.2e-12 47.4 0.0 2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain GAF_2 PF13185.1 KEY67104.1 - 3.2e-05 24.4 0.0 4.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 KEY67104.1 - 0.081 13.0 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 GAF domain LETM1 PF07766.8 KEY67105.1 - 6.2e-08 32.0 0.6 1e-06 27.9 0.1 2.0 2 0 0 2 2 2 2 LETM1-like protein SCP2 PF02036.12 KEY67106.1 - 1.8e-21 76.2 0.3 2.1e-21 76.0 0.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 KEY67106.1 - 0.00011 22.2 0.1 0.00016 21.6 0.1 1.4 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal NMO PF03060.10 KEY67107.1 - 1.8e-37 129.2 6.4 6.5e-35 120.8 4.5 2.3 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 KEY67107.1 - 4.5e-07 29.0 2.7 6.9e-07 28.4 1.9 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KEY67107.1 - 1.1e-06 27.8 5.3 6e-06 25.3 3.7 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KEY67107.1 - 0.00013 21.0 1.0 0.00021 20.3 0.7 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase OpuAC PF04069.7 KEY67107.1 - 0.024 13.9 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system PcrB PF01884.12 KEY67107.1 - 1.3 8.2 4.2 1.6 7.8 0.6 2.3 1 1 1 2 2 2 0 PcrB family Aldo_ket_red PF00248.16 KEY67108.1 - 3.6e-67 226.1 0.0 4.1e-67 225.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FliG_M PF14841.1 KEY67108.1 - 0.097 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 FliG middle domain Pkinase PF00069.20 KEY67109.1 - 5.3e-35 120.8 0.0 7.1e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY67109.1 - 8.5e-14 51.2 0.0 1.2e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEY67109.1 - 0.019 14.7 0.6 0.73 9.5 0.0 2.6 2 2 1 3 3 3 0 Phosphotransferase enzyme family EMP24_GP25L PF01105.19 KEY67110.1 - 2.1e-49 167.7 0.0 2.4e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Atrophin-1 PF03154.10 KEY67112.1 - 1.5 6.8 9.8 1.6 6.8 6.8 1.0 1 0 0 1 1 1 0 Atrophin-1 family Pec_lyase_C PF00544.14 KEY67113.1 - 1.6e-16 60.3 3.3 3.2e-16 59.4 2.3 1.6 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KEY67113.1 - 8e-06 25.6 9.1 2.6e-05 24.0 6.1 2.0 1 1 1 2 2 2 2 Right handed beta helix region Arrestin_C PF02752.17 KEY67115.1 - 0.00071 19.6 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain DUF2790 PF10976.3 KEY67115.1 - 0.0081 15.9 0.0 0.1 12.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2790) Arrestin_N PF00339.24 KEY67115.1 - 0.085 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Fungal_trans PF04082.13 KEY67116.1 - 7e-13 48.0 1.2 7e-13 48.0 0.8 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY67116.1 - 4.4e-07 29.6 10.0 4.4e-07 29.6 6.9 3.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_UL25 PF01499.11 KEY67116.1 - 0.12 10.6 0.1 0.18 10.0 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Acetyltransf_7 PF13508.1 KEY67117.1 - 1.4e-06 28.3 0.0 2.2e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEY67117.1 - 4.8e-06 26.5 0.0 7.6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KEY67117.1 - 0.0002 21.4 0.0 0.00046 20.2 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEY67117.1 - 0.1 12.4 0.0 0.4 10.5 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain TatC PF00902.13 KEY67118.1 - 0.0047 16.3 0.5 0.072 12.4 0.4 2.1 2 0 0 2 2 2 1 Sec-independent protein translocase protein (TatC) AA_permease_2 PF13520.1 KEY67119.1 - 4.3e-43 147.4 56.8 5.4e-43 147.1 39.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEY67119.1 - 3.6e-23 81.6 51.3 9.2e-22 77.0 36.2 2.0 1 1 0 1 1 1 1 Amino acid permease DUF2512 PF10710.4 KEY67119.1 - 7.4 6.0 14.6 0.09 12.2 1.2 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2512) MFS_1 PF07690.11 KEY67120.1 - 2.6e-30 105.3 16.1 2.6e-30 105.3 11.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily FMO-like PF00743.14 KEY67121.1 - 1.1e-28 99.8 0.0 1.7e-16 59.5 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KEY67121.1 - 3.3e-20 73.0 0.1 3.2e-19 69.8 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEY67121.1 - 6.5e-11 41.7 0.1 8.3e-08 31.5 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KEY67121.1 - 5e-07 29.8 0.0 7.5e-05 22.6 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEY67121.1 - 3.1e-06 27.0 0.6 2.6e-05 24.0 0.1 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KEY67121.1 - 2.2e-05 24.3 0.0 6.4e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KEY67121.1 - 0.013 15.8 2.6 0.91 9.9 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEY67121.1 - 0.016 14.3 0.2 0.059 12.4 0.0 1.9 2 0 0 2 2 2 0 Thi4 family DAO PF01266.19 KEY67121.1 - 0.034 13.0 0.3 6.5 5.5 0.0 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase GMC_oxred_N PF00732.14 KEY67122.1 - 6.4e-57 192.9 0.0 8.3e-57 192.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY67122.1 - 2.3e-32 112.2 0.0 4e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KEY67122.1 - 0.0037 16.1 0.0 0.1 11.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KEY67122.1 - 0.019 13.9 0.0 0.035 13.0 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.19 KEY67122.1 - 0.024 13.5 0.0 0.54 9.0 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEY67122.1 - 0.035 14.1 0.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY67122.1 - 0.035 14.1 0.2 0.095 12.7 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KEY67122.1 - 0.089 11.8 0.0 0.31 10.0 0.0 1.8 2 0 0 2 2 2 0 Thi4 family MFS_1 PF07690.11 KEY67123.1 - 4.3e-37 127.6 75.2 7.7e-34 116.9 34.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY67123.1 - 2.5e-07 29.6 42.5 0.00022 19.9 11.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Aldo_ket_red PF00248.16 KEY67124.1 - 3.7e-52 176.9 0.0 4.4e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Leu_Phe_trans PF03588.9 KEY67124.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase Ribosomal_S5 PF00333.15 KEY67124.1 - 0.14 11.9 0.2 0.78 9.5 0.0 2.1 1 1 1 2 2 2 0 Ribosomal protein S5, N-terminal domain adh_short PF00106.20 KEY67125.1 - 3.9e-22 78.9 0.5 6.6e-22 78.1 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY67125.1 - 6.4e-13 49.0 0.2 1.8e-12 47.5 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY67125.1 - 7.3e-07 29.0 1.1 2.4e-06 27.3 0.6 1.8 1 1 1 2 2 2 1 KR domain 3HCDH_N PF02737.13 KEY67125.1 - 0.025 14.2 0.1 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Nitro_FeMo-Co PF02579.12 KEY67125.1 - 0.068 13.2 0.1 0.88 9.6 0.0 2.3 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Glyco_transf_5 PF08323.6 KEY67125.1 - 0.069 12.6 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Starch synthase catalytic domain DFP PF04127.10 KEY67125.1 - 0.08 12.5 0.2 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein NmrA PF05368.8 KEY67126.1 - 5.9e-14 51.8 0.2 7.7e-14 51.4 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY67126.1 - 6.6e-08 32.7 0.1 1.2e-07 31.8 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KEY67126.1 - 3.8e-05 23.6 0.6 7.1e-05 22.7 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KEY67126.1 - 0.00012 21.6 0.0 0.0015 18.0 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 KEY67126.1 - 0.00024 20.9 0.4 0.00085 19.2 0.2 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 KEY67126.1 - 0.00043 20.2 0.2 0.00085 19.3 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 KEY67126.1 - 0.00071 19.2 0.1 0.0016 18.1 0.1 1.5 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 KEY67126.1 - 0.0055 17.1 0.2 0.06 13.7 0.3 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.7 KEY67126.1 - 0.023 13.6 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Saccharop_dh PF03435.13 KEY67126.1 - 0.025 13.5 0.2 0.043 12.8 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KEY67126.1 - 0.053 13.6 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 KEY67126.1 - 0.15 10.7 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ribosomal_S13 PF00416.17 KEY67127.1 - 1.3e-41 141.4 1.6 1.5e-41 141.1 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 KEY67127.1 - 0.0085 14.6 0.0 0.0087 14.6 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.4 KEY67127.1 - 0.097 12.7 0.5 0.21 11.6 0.4 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 SBDS_C PF09377.5 KEY67128.1 - 2e-49 166.4 0.1 3e-49 165.8 0.1 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 KEY67128.1 - 3e-30 103.8 0.2 5e-30 103.1 0.1 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein tRNA-synt_1b PF00579.20 KEY67129.1 - 4.1e-23 81.9 0.3 1.5e-19 70.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Ldh_1_C PF02866.13 KEY67129.1 - 0.048 13.3 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Peptidase_S10 PF00450.17 KEY67130.1 - 1.7e-127 426.0 0.5 2.1e-127 425.7 0.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KEY67130.1 - 0.00013 21.8 0.0 0.002 18.0 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Carbpep_Y_N PF05388.6 KEY67130.1 - 0.0014 18.7 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide ELO PF01151.13 KEY67131.1 - 1.4e-81 273.4 5.9 1.7e-81 273.1 4.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family FYVE PF01363.16 KEY67132.1 - 4.5e-16 58.5 8.3 7.3e-16 57.8 5.7 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 KEY67132.1 - 0.25 11.2 13.0 0.077 12.8 5.6 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger zf-RING_5 PF14634.1 KEY67132.1 - 3.5 7.4 9.5 14 5.4 0.2 2.4 2 0 0 2 2 2 0 zinc-RING finger domain MoaC PF01967.16 KEY67133.1 - 1.4e-52 176.9 2.1 2.9e-52 175.9 1.4 1.5 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 KEY67133.1 - 4.6e-35 120.1 0.0 1.9e-34 118.0 0.0 2.0 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 KEY67133.1 - 2e-18 67.0 0.0 5.1e-18 65.8 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.1 KEY67133.1 - 0.00015 21.8 0.0 0.00039 20.5 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KEY67133.1 - 0.00057 19.8 0.0 0.0017 18.3 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain IKI3 PF04762.7 KEY67134.1 - 0.19 9.5 0.0 3.4 5.3 0.0 2.4 3 0 0 3 3 3 0 IKI3 family RRM_6 PF14259.1 KEY67135.1 - 9.6e-11 41.5 0.0 0.0006 19.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEY67135.1 - 2.9e-10 39.6 0.0 0.00081 18.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY67135.1 - 0.00022 20.9 0.0 0.91 9.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GutM PF06923.6 KEY67135.1 - 0.015 14.9 0.1 0.057 13.0 0.1 1.8 2 0 0 2 2 2 0 Glucitol operon activator protein (GutM) HEAT_2 PF13646.1 KEY67137.1 - 3.6e-15 56.0 1.4 0.00044 20.4 0.0 7.3 7 0 0 7 7 7 4 HEAT repeats HEAT PF02985.17 KEY67137.1 - 1.9e-08 33.6 10.2 0.25 11.5 0.0 8.8 8 0 0 8 8 8 3 HEAT repeat Vac14_Fab1_bd PF12755.2 KEY67137.1 - 7.1e-07 29.5 0.0 0.028 14.8 0.0 5.0 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Transcrip_reg PF01709.15 KEY67138.1 - 1.3e-49 168.4 0.0 1.5e-49 168.2 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator Flagellin_N PF00669.15 KEY67138.1 - 0.055 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region DUF2346 PF09803.4 KEY67139.1 - 0.017 14.9 6.5 0.031 14.1 4.5 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) HHH PF00633.18 KEY67141.1 - 0.0075 15.9 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif NUDIX_2 PF13869.1 KEY67142.1 - 5.4e-79 263.9 0.0 6.4e-79 263.6 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase UPF0047 PF01894.12 KEY67143.1 - 2.6e-40 136.9 0.0 3.7e-40 136.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 zf-CHCC PF10276.4 KEY67143.1 - 6.7e-16 57.8 1.2 1.2e-15 57.0 0.8 1.4 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 KEY67143.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb DUF2946 PF11162.3 KEY67143.1 - 0.068 13.3 0.7 0.19 11.9 0.0 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2946) CDC45 PF02724.9 KEY67144.1 - 0.021 12.9 8.9 0.035 12.1 6.1 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF1509 PF07420.6 KEY67144.1 - 0.33 10.1 11.9 0.49 9.6 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Apt1 PF10351.4 KEY67144.1 - 2.6 6.7 10.1 4.2 6.1 7.0 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peptidase_M16 PF00675.15 KEY67145.1 - 8.1e-33 113.2 0.4 2.4e-32 111.7 0.1 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KEY67145.1 - 2.7e-29 102.1 0.0 4.2e-16 59.1 0.0 4.1 4 0 0 4 4 4 2 Peptidase M16 inactive domain DUF2202 PF09968.4 KEY67145.1 - 0.039 13.6 0.1 0.097 12.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) UCH PF00443.24 KEY67146.1 - 1.3e-75 253.9 0.0 6.4e-75 251.7 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEY67146.1 - 3.1e-18 66.2 0.0 7e-09 35.5 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KEY67146.1 - 2.8e-09 37.2 0.0 2.4e-08 34.2 0.0 2.6 2 0 0 2 2 2 1 DUSP domain ubiquitin PF00240.18 KEY67146.1 - 0.011 15.0 0.0 0.032 13.6 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin family Ubiquitin_2 PF14560.1 KEY67146.1 - 0.12 12.6 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Zn-ribbon_8 PF09723.5 KEY67146.1 - 0.48 10.4 1.9 15 5.6 0.4 2.5 2 0 0 2 2 2 0 Zinc ribbon domain PDEase_I PF00233.14 KEY67147.1 - 9.6e-44 149.9 0.2 7e-41 140.5 0.0 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase BSD PF03909.12 KEY67147.1 - 0.15 11.7 0.1 0.36 10.6 0.1 1.6 1 0 0 1 1 1 0 BSD domain GMC_oxred_N PF00732.14 KEY67148.1 - 6.4e-40 137.1 0.9 1e-39 136.4 0.6 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY67148.1 - 2.7e-27 95.8 0.7 9.1e-27 94.1 0.1 2.1 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 KEY67148.1 - 3.8e-08 32.6 7.2 9.9e-07 27.9 5.0 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEY67148.1 - 1.7e-07 30.4 0.5 1.7e-06 27.1 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KEY67148.1 - 6.1e-07 29.3 0.2 1.8e-06 27.8 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KEY67148.1 - 3.7e-06 26.9 0.3 1.5e-05 24.9 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEY67148.1 - 0.00013 21.2 0.1 0.00023 20.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KEY67148.1 - 0.0008 17.9 0.2 0.0013 17.3 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 KEY67148.1 - 0.0041 16.2 0.1 0.0041 16.2 0.1 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 KEY67148.1 - 0.0071 16.7 0.2 0.13 12.7 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEY67148.1 - 0.014 14.4 0.8 0.022 13.8 0.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEY67148.1 - 0.051 12.4 0.1 0.087 11.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 KEY67148.1 - 0.075 12.6 0.1 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 KEY67148.1 - 0.14 11.0 0.1 0.24 10.1 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.9 KEY67148.1 - 0.18 11.1 1.3 0.37 10.1 0.9 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NERD PF08378.6 KEY67149.1 - 0.12 12.6 0.1 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Nuclease-related domain C_GCAxxG_C_C PF09719.5 KEY67149.1 - 0.29 10.9 0.1 0.29 10.9 0.1 2.1 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) PAN_4 PF14295.1 KEY67150.1 - 0.07 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 PAN domain DUF3357 PF11837.3 KEY67150.1 - 0.083 12.7 0.1 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Glyco_transf_22 PF03901.12 KEY67151.1 - 1.2e-59 202.3 22.7 1.5e-59 202.1 15.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Skp1 PF01466.14 KEY67152.1 - 2.6e-39 133.1 1.1 2.6e-39 133.1 0.8 1.5 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KEY67152.1 - 9.8e-21 73.6 0.1 2.1e-20 72.5 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 KEY67152.1 - 0.0052 16.7 0.9 0.0079 16.1 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4375) Ribosomal_L39 PF00832.15 KEY67153.1 - 8.9e-23 79.4 9.2 1e-22 79.3 6.4 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Asp PF00026.18 KEY67154.1 - 2.3e-69 234.0 0.8 2.8e-69 233.8 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEY67154.1 - 8.7e-12 45.2 0.8 2.2e-11 43.9 0.2 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KEY67154.1 - 8e-06 25.4 0.0 2.9e-05 23.6 0.0 1.9 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KEY67154.1 - 8.1e-06 26.2 0.1 0.027 14.9 0.0 3.6 2 1 0 2 2 2 2 Aspartyl protease PBP PF01161.15 KEY67155.1 - 1.6e-22 79.8 0.0 2.2e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein 2OG-FeII_Oxy_3 PF13640.1 KEY67156.1 - 0.00015 22.1 0.2 0.00049 20.5 0.1 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KEY67156.1 - 0.0018 18.5 0.0 0.011 16.0 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 KEY67157.1 - 3.9e-15 55.4 0.0 1.2e-14 53.8 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY67157.1 - 1.3e-10 41.0 9.1 2.5e-10 40.1 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeobox_KN PF05920.6 KEY67158.1 - 1.1e-21 76.1 0.5 2.9e-21 74.8 0.4 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KEY67158.1 - 7e-09 35.1 1.2 1.6e-08 34.0 0.8 1.6 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KEY67158.1 - 0.0036 16.3 0.3 2.1 7.4 0.1 2.6 2 1 0 2 2 2 2 Homeodomain leucine-zipper encoding, Homez Homeobox PF00046.24 KEY67159.1 - 2e-06 27.3 0.2 8.4e-06 25.3 0.0 2.1 2 0 0 2 2 2 1 Homeobox domain Rhodanese PF00581.15 KEY67159.1 - 2.2e-06 28.0 0.0 5.6e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain PIG-X PF08320.7 KEY67160.1 - 2.8e-67 226.0 0.0 3.9e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 AAA_2 PF07724.9 KEY67161.1 - 7.8e-47 159.3 0.0 3.5e-45 153.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KEY67161.1 - 3.1e-27 95.3 0.2 7.8e-15 55.2 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KEY67161.1 - 1.2e-23 82.8 0.9 1.2e-23 82.8 0.6 2.5 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 KEY67161.1 - 4.7e-17 62.5 9.7 2.7e-06 27.4 0.0 6.2 3 2 3 6 6 6 2 AAA ATPase domain AAA_5 PF07728.9 KEY67161.1 - 2.3e-16 59.8 0.0 2.2e-10 40.4 0.0 3.2 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEY67161.1 - 2.8e-14 53.3 0.7 4.1e-05 23.7 0.0 4.7 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 KEY67161.1 - 7.7e-10 38.4 0.0 6.4e-06 25.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 KEY67161.1 - 1.5e-09 38.7 3.2 0.0016 19.2 0.8 3.9 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KEY67161.1 - 1.8e-07 30.7 1.3 0.022 14.5 0.0 3.6 3 0 0 3 3 3 2 Part of AAA domain AAA_14 PF13173.1 KEY67161.1 - 1.9e-07 30.9 0.0 0.026 14.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain Clp_N PF02861.15 KEY67161.1 - 3.1e-07 30.2 2.0 0.0002 21.2 0.0 4.0 4 0 0 4 4 3 1 Clp amino terminal domain IstB_IS21 PF01695.12 KEY67161.1 - 5.6e-07 29.1 0.0 0.023 14.1 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 KEY67161.1 - 8e-06 26.1 8.0 0.0069 16.7 0.0 4.2 4 2 2 6 6 3 2 AAA domain Mg_chelatase PF01078.16 KEY67161.1 - 1.6e-05 24.1 0.1 0.19 10.8 0.1 3.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KEY67161.1 - 2e-05 24.5 0.4 0.21 11.5 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.1 KEY67161.1 - 3.1e-05 23.8 0.1 0.19 11.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain MobB PF03205.9 KEY67161.1 - 4.3e-05 23.2 0.0 0.38 10.4 0.0 3.0 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 KEY67161.1 - 4.7e-05 22.4 0.5 0.0066 15.3 0.2 2.7 2 1 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.17 KEY67161.1 - 4.8e-05 23.4 0.0 0.47 10.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 KEY67161.1 - 8.6e-05 22.0 0.6 0.97 8.8 0.0 4.0 3 1 1 4 4 4 2 AAA domain AAA_3 PF07726.6 KEY67161.1 - 9.6e-05 21.9 0.0 0.63 9.6 0.0 3.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 KEY67161.1 - 0.0002 21.2 0.0 0.15 11.9 0.0 3.6 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 KEY67161.1 - 0.00029 20.6 17.1 0.0098 15.6 0.2 5.8 3 3 0 4 4 4 1 Archaeal ATPase Zeta_toxin PF06414.7 KEY67161.1 - 0.00031 19.8 0.0 0.038 13.0 0.0 3.0 3 0 0 3 3 2 1 Zeta toxin ABC_tran PF00005.22 KEY67161.1 - 0.00071 19.8 0.3 1 9.6 0.0 3.3 3 0 0 3 3 3 1 ABC transporter AAA_24 PF13479.1 KEY67161.1 - 0.00077 19.1 0.0 2.5 7.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 KEY67161.1 - 0.00082 18.5 0.0 0.4 9.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 KEY67161.1 - 0.001 18.7 0.0 0.19 11.3 0.0 3.2 3 0 0 3 3 2 1 NACHT domain AAA_29 PF13555.1 KEY67161.1 - 0.0013 18.2 0.0 1.1 8.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NTPase_1 PF03266.10 KEY67161.1 - 0.0014 18.3 0.1 0.2 11.3 0.0 3.7 4 0 0 4 4 3 1 NTPase AAA_10 PF12846.2 KEY67161.1 - 0.0019 17.7 4.2 0.32 10.4 0.0 4.4 4 2 0 5 5 4 1 AAA-like domain Torsin PF06309.6 KEY67161.1 - 0.0029 17.4 0.0 0.016 15.1 0.0 2.1 2 0 0 2 2 2 1 Torsin V_ATPase_I PF01496.14 KEY67161.1 - 0.014 13.3 4.3 0.026 12.4 2.9 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_21 PF13304.1 KEY67161.1 - 0.021 14.8 0.7 2.6 7.9 0.0 3.2 4 0 0 4 4 3 0 AAA domain SRP54 PF00448.17 KEY67161.1 - 0.022 14.2 0.0 4.3 6.7 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain UPF0079 PF02367.12 KEY67161.1 - 0.034 13.7 0.0 8.4 6.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_1 PF03029.12 KEY67161.1 - 0.056 12.9 0.0 6.6 6.1 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 KEY67161.1 - 0.067 13.1 0.4 1.1 9.2 0.0 3.2 3 2 0 3 3 2 0 50S ribosome-binding GTPase Glyco_hydro_47 PF01532.15 KEY67161.1 - 0.1 11.2 0.1 0.2 10.2 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 47 DUF1640 PF07798.6 KEY67161.1 - 0.46 10.5 7.1 1.2 9.1 4.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Macoilin PF09726.4 KEY67161.1 - 1.8 6.7 9.4 3.1 5.9 6.5 1.3 1 0 0 1 1 1 0 Transmembrane protein IncA PF04156.9 KEY67161.1 - 1.9 8.0 12.4 5.5 6.5 8.6 1.8 1 0 0 1 1 1 0 IncA protein Spc7 PF08317.6 KEY67161.1 - 6.1 5.4 13.5 26 3.3 9.7 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein AAA_23 PF13476.1 KEY67161.1 - 6.8 6.9 19.4 1.8 8.8 0.2 4.0 3 2 0 3 3 2 0 AAA domain Mhr1 PF12829.2 KEY67162.1 - 3.9e-27 93.9 0.1 7.3e-27 93.0 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Sulfotransfer_3 PF13469.1 KEY67163.1 - 0.00071 20.5 0.0 0.0014 19.5 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family PDT PF00800.13 KEY67164.1 - 3.8e-66 222.0 0.0 4.8e-66 221.7 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 KEY67164.1 - 0.002 17.5 0.0 0.0046 16.4 0.0 1.6 1 0 0 1 1 1 1 ACT domain DUF4644 PF15486.1 KEY67164.1 - 0.046 13.6 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) Pkinase PF00069.20 KEY67165.1 - 4.9e-68 229.0 0.0 7.7e-68 228.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY67165.1 - 1.7e-49 168.2 0.0 2.6e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 KEY67165.1 - 1.6e-28 98.7 0.0 3.4e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 KEY67165.1 - 3.4e-16 58.8 0.1 7.5e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KEY67165.1 - 5.6e-15 55.2 0.1 9.9e-15 54.4 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 KEY67165.1 - 1.3e-12 48.0 0.0 2.4e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.1 KEY67165.1 - 6.4e-08 31.8 0.0 9.2e-05 21.5 0.0 2.4 2 0 0 2 2 2 2 Kinase-like SAM_PNT PF02198.11 KEY67165.1 - 0.038 13.7 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Kdo PF06293.9 KEY67165.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AIG2_2 PF13772.1 KEY67166.1 - 3.7e-06 26.9 0.1 6.5e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 AIG2-like family AIG2 PF06094.7 KEY67166.1 - 3.3e-05 24.2 0.0 4.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family EBP PF05241.7 KEY67168.1 - 1.4e-60 203.6 10.3 1.7e-60 203.3 7.2 1.0 1 0 0 1 1 1 1 Emopamil binding protein zf-DHHC PF01529.15 KEY67168.1 - 1.6 8.1 4.4 6.2 6.1 0.1 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase Nup88 PF10168.4 KEY67170.1 - 0.11 10.2 4.6 0.58 7.9 0.0 2.2 2 0 0 2 2 2 0 Nuclear pore component WD40 PF00400.27 KEY67170.1 - 0.14 12.0 0.3 4.6 7.2 0.1 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat RRM_1 PF00076.17 KEY67171.1 - 1.8e-16 59.5 0.0 3e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY67171.1 - 4.4e-13 48.9 0.0 6.5e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY67171.1 - 1.1e-08 34.7 0.1 1.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L31 PF09784.4 KEY67172.1 - 2.1e-45 152.9 1.2 2.3e-45 152.8 0.8 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Sedlin_N PF04628.8 KEY67173.1 - 2.8e-36 124.2 0.0 7.1e-36 122.9 0.0 1.6 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 KEY67173.1 - 0.017 14.8 0.0 0.38 10.4 0.0 2.1 1 1 1 2 2 2 0 Sybindin-like family Histone PF00125.19 KEY67174.1 - 1.8e-15 56.7 0.1 2.2e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KEY67174.1 - 0.00011 22.0 0.1 0.00016 21.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KEY67174.1 - 0.00013 22.0 0.1 0.00018 21.5 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KEY67174.1 - 0.00019 21.4 0.1 0.00033 20.6 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KEY67174.1 - 0.019 14.6 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KEY67174.1 - 0.024 13.8 0.0 0.025 13.8 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TPR_11 PF13414.1 KEY67175.1 - 1.5e-38 130.2 16.9 1.9e-10 40.2 0.2 7.6 5 2 2 7 7 7 7 TPR repeat TPR_1 PF00515.23 KEY67175.1 - 1.6e-32 109.7 18.1 2e-07 30.3 0.0 9.7 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_2 PF07719.12 KEY67175.1 - 1.4e-28 96.4 23.1 1.4e-05 24.6 0.0 10.5 12 0 0 12 12 11 7 Tetratricopeptide repeat Apc3 PF12895.2 KEY67175.1 - 2.6e-28 97.9 17.8 5.2e-21 74.5 0.6 4.7 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KEY67175.1 - 1.1e-24 86.4 24.6 2.2e-08 34.5 0.2 8.0 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 KEY67175.1 - 2e-22 79.2 9.2 1.9e-05 24.9 1.1 6.7 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEY67175.1 - 8e-21 72.2 0.0 0.18 11.6 0.0 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.1 KEY67175.1 - 1.9e-20 72.5 17.9 2.7e-06 27.2 0.2 7.4 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 KEY67175.1 - 5.1e-19 66.8 14.8 0.0082 16.2 0.2 9.8 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_7 PF13176.1 KEY67175.1 - 2.7e-18 64.2 8.1 0.00047 19.7 0.0 7.6 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 KEY67175.1 - 1.7e-17 62.3 15.8 0.17 12.6 0.1 10.0 4 2 6 10 10 10 5 Tetratricopeptide repeat TPR_6 PF13174.1 KEY67175.1 - 6.2e-09 35.7 14.1 2.2 8.9 0.2 9.0 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEY67175.1 - 1.1e-06 28.3 13.1 0.049 13.4 0.3 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 KEY67175.1 - 3.6e-05 22.9 11.5 0.011 14.8 1.7 4.3 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 KEY67175.1 - 5.7e-05 23.1 1.9 0.1 12.7 0.3 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.3 KEY67175.1 - 0.0065 15.2 3.8 0.66 8.6 0.1 4.1 5 0 0 5 5 5 1 NMDA receptor-regulated protein 1 MIT PF04212.13 KEY67175.1 - 0.3 10.9 4.1 2.6 8.0 0.1 4.1 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain BTAD PF03704.12 KEY67175.1 - 0.34 11.1 11.6 32 4.7 0.1 4.5 4 0 0 4 4 4 0 Bacterial transcriptional activator domain DUF788 PF05620.6 KEY67176.1 - 8.8e-42 142.8 0.1 9.7e-42 142.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Abi PF02517.11 KEY67176.1 - 0.14 12.3 2.5 7.6 6.7 0.0 2.1 2 0 0 2 2 2 0 CAAX protease self-immunity DUF3605 PF12239.3 KEY67177.1 - 1.2e-59 200.6 0.0 1.5e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Chal_sti_synt_N PF00195.14 KEY67177.1 - 0.013 14.7 0.0 0.026 13.7 0.0 1.5 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Abhydrolase_3 PF07859.8 KEY67178.1 - 2.2e-20 73.1 0.0 3e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KEY67178.1 - 4.3e-20 71.6 0.0 1.8e-14 53.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) COesterase PF00135.23 KEY67178.1 - 0.0032 16.2 1.3 1.3 7.6 0.4 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 KEY67178.1 - 0.054 13.2 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family CBFD_NFYB_HMF PF00808.18 KEY67179.1 - 4.4e-13 49.0 1.2 6.3e-13 48.5 0.8 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KEY67179.1 - 3.9e-05 23.6 0.1 5.9e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PI3_PI4_kinase PF00454.22 KEY67180.1 - 7.9e-31 107.3 0.0 1.5e-30 106.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 KEY67180.1 - 4.8e-20 71.0 0.0 1e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 KEY67180.1 - 0.18 10.9 0.2 0.36 9.9 0.1 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) zf-C3HC4_3 PF13920.1 KEY67181.1 - 0.0015 18.1 11.6 0.0024 17.4 8.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.10 KEY67181.1 - 0.095 12.6 0.0 0.27 11.2 0.0 1.8 1 0 0 1 1 1 0 U-box domain zf-RING_6 PF14835.1 KEY67181.1 - 0.23 11.2 6.9 0.36 10.6 4.8 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 KEY67181.1 - 1.8 8.3 12.7 2.9 7.6 8.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEY67181.1 - 3.5 7.7 13.8 5.7 7.0 9.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ras PF00071.17 KEY67182.1 - 4e-58 195.3 0.0 4.7e-58 195.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEY67182.1 - 3.2e-20 72.7 0.0 5.1e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEY67182.1 - 3.5e-14 52.4 0.0 5.6e-14 51.7 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEY67182.1 - 1.3e-06 27.6 0.0 1.6e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KEY67182.1 - 2.1e-06 27.3 0.0 5e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEY67182.1 - 0.00011 22.1 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KEY67182.1 - 0.0063 16.5 0.0 0.0087 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEY67182.1 - 0.029 14.4 0.1 0.21 11.7 0.0 2.1 2 1 0 2 2 2 0 AAA domain Kri1_C PF12936.2 KEY67183.1 - 9.1e-27 92.8 0.1 9.1e-27 92.8 0.1 3.6 4 0 0 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.7 KEY67183.1 - 7.8e-25 87.0 18.4 7.8e-25 87.0 12.8 4.8 6 0 0 6 6 6 1 KRI1-like family DUF4381 PF14316.1 KEY67183.1 - 0.44 10.6 2.5 1.2 9.2 1.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) LRR19-TM PF15176.1 KEY67183.1 - 1.3 8.7 4.4 1.3 8.7 0.6 2.6 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain YycI PF09648.5 KEY67183.1 - 1.7 8.0 6.6 0.24 10.8 1.6 1.7 2 0 0 2 2 2 0 YycH protein Fungal_trans PF04082.13 KEY67184.1 - 1.5e-29 102.6 0.1 2.9e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY67184.1 - 1.7e-09 37.4 10.9 2.7e-09 36.7 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_C50 PF03568.12 KEY67185.1 - 1.8e-115 385.7 0.0 4.6e-115 384.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase family C50 TPR_12 PF13424.1 KEY67185.1 - 4.7e-07 29.6 3.7 0.13 12.2 0.0 6.7 6 1 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEY67185.1 - 1.1e-06 28.6 0.2 7 7.5 0.0 7.2 5 1 1 6 6 6 1 Tetratricopeptide repeat DUF3602 PF12223.3 KEY67185.1 - 0.033 14.5 0.2 0.21 11.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) TPR_2 PF07719.12 KEY67185.1 - 0.063 13.2 0.7 7.4 6.7 0.0 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3708 PF12501.3 KEY67186.1 - 0.021 14.6 0.7 0.031 14.1 0.5 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter SIR2 PF02146.12 KEY67187.1 - 3.2e-29 101.9 0.0 5.3e-29 101.2 0.0 1.3 1 1 0 1 1 1 1 Sir2 family Cation_efflux PF01545.16 KEY67189.1 - 1.3e-54 185.2 1.5 1.6e-54 184.9 1.0 1.0 1 0 0 1 1 1 1 Cation efflux family FGGY_C PF02782.11 KEY67190.1 - 1.3e-24 86.9 0.1 4.6e-24 85.1 0.0 2.0 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KEY67190.1 - 1.2e-21 77.1 0.0 3.7e-14 52.6 0.0 2.5 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Cwf_Cwc_15 PF04889.7 KEY67191.1 - 1.2e-81 274.0 21.8 1.4e-81 273.8 15.1 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF2890 PF11081.3 KEY67191.1 - 0.063 13.3 18.5 0.041 13.9 9.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) GEMIN8 PF15348.1 KEY67191.1 - 0.21 11.5 10.8 0.27 11.2 7.5 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 CAF-1_p150 PF11600.3 KEY67191.1 - 0.28 10.5 19.1 0.47 9.7 13.2 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Tom37_C PF11801.3 KEY67191.1 - 0.54 10.1 11.7 0.095 12.5 5.3 1.7 2 0 0 2 2 2 0 Tom37 C-terminal domain SDA1 PF05285.7 KEY67191.1 - 0.57 9.4 28.0 0.76 8.9 19.4 1.2 1 0 0 1 1 1 0 SDA1 eIF-3c_N PF05470.7 KEY67191.1 - 2.4 6.1 15.7 3.7 5.5 10.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus YqfQ PF14181.1 KEY67191.1 - 3.3 7.7 9.0 17 5.4 5.5 2.1 2 0 0 2 2 2 0 YqfQ-like protein OmpH PF03938.9 KEY67191.1 - 4.4 7.2 10.1 7.2 6.5 7.0 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6 PF04111.7 KEY67191.1 - 4.7 6.1 11.6 5.8 5.8 8.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Nop14 PF04147.7 KEY67191.1 - 6.5 4.5 30.6 8.3 4.1 21.2 1.3 1 0 0 1 1 1 0 Nop14-like family RNase_PH PF01138.16 KEY67192.1 - 1.2e-25 90.2 0.0 2.1e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KEY67192.1 - 4e-08 33.0 0.0 6.3e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Arf PF00025.16 KEY67193.1 - 2e-40 137.8 0.0 3.1e-40 137.2 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KEY67193.1 - 1.1e-13 50.7 0.0 1.3e-09 37.2 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KEY67193.1 - 4.9e-09 35.7 0.0 1.2e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KEY67193.1 - 6.6e-09 35.2 0.0 7.5e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KEY67193.1 - 1.5e-07 30.7 0.0 3e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KEY67193.1 - 2.7e-05 23.6 0.1 8e-05 22.1 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KEY67193.1 - 3.4e-05 24.3 0.0 0.00034 21.0 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KEY67193.1 - 0.0009 19.1 0.0 0.0014 18.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Na_H_Exchanger PF00999.16 KEY67194.1 - 2.6e-70 236.8 42.6 3.1e-70 236.6 29.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family HSA PF07529.8 KEY67195.1 - 4.1e-19 68.1 1.3 4.1e-19 68.1 0.9 3.4 3 1 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.1 KEY67195.1 - 2.1e-15 56.5 0.3 2.1e-15 56.5 0.2 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain OATP PF03137.15 KEY67195.1 - 8.2 4.3 5.5 13 3.6 3.8 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Polyoma_coat2 PF00761.15 KEY67195.1 - 8.4 5.7 14.6 18 4.6 10.1 1.5 1 0 0 1 1 1 0 Polyomavirus coat protein Fer2_3 PF13085.1 KEY67196.1 - 1.4e-31 108.5 0.0 2.4e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 KEY67196.1 - 7.6e-10 38.9 7.9 7.6e-10 38.9 5.4 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 KEY67196.1 - 3e-09 36.7 5.3 3e-09 36.7 3.7 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 KEY67196.1 - 4e-06 27.1 2.2 4e-06 27.1 1.5 2.8 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 KEY67196.1 - 3.6e-05 23.4 4.8 3.6e-05 23.4 3.3 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 KEY67196.1 - 5.6e-05 23.3 5.3 0.025 14.8 0.6 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 KEY67196.1 - 0.00094 18.8 2.6 0.003 17.2 0.2 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 KEY67196.1 - 0.008 16.5 6.5 0.008 16.5 4.5 2.5 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 KEY67196.1 - 3.8 8.1 6.6 1.4 9.5 0.1 2.6 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_2 PF12797.2 KEY67196.1 - 4 7.5 17.7 1.7 8.7 3.1 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain G-patch_2 PF12656.2 KEY67197.1 - 1.4e-22 79.2 0.6 1.4e-22 79.2 0.4 4.1 4 2 2 6 6 6 1 DExH-box splicing factor binding site PRP38_assoc PF12871.2 KEY67197.1 - 0.00053 20.4 39.5 0.00053 20.4 27.4 3.3 2 1 0 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term G-patch PF01585.18 KEY67197.1 - 0.023 14.4 2.4 0.2 11.4 1.7 2.6 1 1 0 1 1 1 0 G-patch domain Kinetochor_Ybp2 PF08568.5 KEY67198.1 - 5.6e-100 335.4 0.0 6.8e-100 335.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin THDPS_M PF14789.1 KEY67198.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase middle DNA_pol_A PF00476.15 KEY67199.1 - 4.1e-101 338.3 0.0 6e-101 337.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 KEY67199.1 - 0.064 12.7 1.1 0.84 9.0 0.1 2.6 2 1 0 2 2 2 0 3'-5' exonuclease DUF1841 PF08897.6 KEY67199.1 - 0.11 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) zf-C3HC4_3 PF13920.1 KEY67200.1 - 8.7e-11 41.3 9.1 1.3e-10 40.7 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEY67200.1 - 7.1e-09 35.5 10.2 1.2e-08 34.8 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEY67200.1 - 1.1e-08 34.7 10.9 1.8e-08 34.0 7.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KEY67200.1 - 8.4e-06 25.3 10.7 1.4e-05 24.6 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY67200.1 - 3.5e-05 23.4 10.4 6.1e-05 22.6 7.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KEY67200.1 - 3.7e-05 23.4 4.8 7.6e-05 22.4 3.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KEY67200.1 - 0.0013 18.2 5.5 0.0024 17.4 3.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KEY67200.1 - 0.013 15.3 8.7 0.022 14.6 6.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RNHCP PF12647.2 KEY67200.1 - 0.023 14.5 2.2 0.046 13.5 1.5 1.5 1 0 0 1 1 1 0 RNHCP domain zf-rbx1 PF12678.2 KEY67200.1 - 0.038 14.0 4.0 0.074 13.1 2.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger PolC_DP2 PF03833.8 KEY67200.1 - 0.16 9.6 0.9 0.21 9.1 0.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-RING_UBOX PF13445.1 KEY67200.1 - 0.16 11.7 5.8 0.39 10.4 4.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 KEY67200.1 - 0.19 11.3 8.1 1.4 8.5 5.6 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.3 KEY67200.1 - 1.7 8.6 8.9 1.5e+02 2.4 6.2 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-MIZ PF02891.15 KEY67200.1 - 3 7.4 7.7 6.3 6.3 5.4 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF3414 PF11894.3 KEY67201.1 - 0 1310.9 0.2 0 1310.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) DUF1286 PF06939.6 KEY67201.1 - 0.063 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1286) PI3_PI4_kinase PF00454.22 KEY67202.1 - 1.4e-44 152.3 0.0 2.6e-44 151.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 KEY67202.1 - 2.5e-41 141.0 0.0 1.8e-40 138.2 0.0 2.5 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FAT PF02259.18 KEY67202.1 - 4.1e-19 68.7 4.1 1e-18 67.4 2.8 1.7 1 0 0 1 1 1 1 FAT domain FATC PF02260.15 KEY67202.1 - 3.3e-12 45.6 0.0 9.1e-12 44.2 0.0 1.8 1 0 0 1 1 1 1 FATC domain Cullin PF00888.17 KEY67203.1 - 4e-113 379.0 0.0 5.8e-113 378.4 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KEY67203.1 - 5.8e-27 93.3 0.9 1.7e-26 91.8 0.6 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain COesterase PF00135.23 KEY67204.1 - 2.6e-76 257.4 0.0 4.1e-76 256.7 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEY67204.1 - 2.6e-10 40.2 0.2 1.1e-09 38.2 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY67204.1 - 0.0026 17.4 2.3 0.0032 17.2 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEY67204.1 - 0.028 13.6 0.6 0.049 12.8 0.4 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KEY67204.1 - 0.05 13.1 0.0 0.77 9.2 0.0 2.5 2 1 0 2 2 2 0 alpha/beta hydrolase fold Pol_alpha_B_N PF08418.5 KEY67205.1 - 1 8.8 7.8 2 7.9 5.4 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal PIF1 PF05970.9 KEY67206.1 - 8.7e-61 205.8 0.1 1.5e-47 162.3 0.0 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 KEY67206.1 - 7e-16 58.3 0.0 1.9e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEY67206.1 - 2.6e-07 30.8 0.0 7.8e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEY67206.1 - 1.8e-06 27.5 0.8 3.4e-06 26.7 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_16 PF13191.1 KEY67206.1 - 6.5e-05 22.9 0.0 0.00033 20.6 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.1 KEY67206.1 - 7.9e-05 22.7 0.1 0.00038 20.5 0.1 2.2 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 KEY67206.1 - 0.00011 20.1 0.1 0.00039 18.3 0.0 1.7 2 0 0 2 2 2 1 Helicase AAA PF00004.24 KEY67206.1 - 0.00013 22.2 0.4 0.00056 20.1 0.0 2.3 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KEY67206.1 - 0.00026 20.9 0.0 0.00086 19.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KEY67206.1 - 0.00066 19.2 0.1 0.25 10.8 0.0 2.9 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 KEY67206.1 - 0.0012 19.1 0.3 0.0048 17.1 0.0 2.1 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.17 KEY67206.1 - 0.0014 18.8 0.1 0.0046 17.0 0.0 2.0 2 0 0 2 2 1 1 RNA helicase T2SE PF00437.15 KEY67206.1 - 0.0014 17.5 0.0 0.0023 16.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.11 KEY67206.1 - 0.0038 16.4 0.0 0.0098 15.1 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein NACHT PF05729.7 KEY67206.1 - 0.0053 16.4 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_7 PF12775.2 KEY67206.1 - 0.0092 15.0 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 DUF2075 PF09848.4 KEY67206.1 - 0.01 14.8 0.0 0.048 12.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.1 KEY67206.1 - 0.011 15.2 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.1 KEY67206.1 - 0.023 14.2 4.5 0.024 14.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain AFG1_ATPase PF03969.11 KEY67206.1 - 0.024 13.4 0.0 0.07 11.9 0.0 1.8 2 0 0 2 2 2 0 AFG1-like ATPase Mg_chelatase PF01078.16 KEY67206.1 - 0.032 13.3 0.0 0.061 12.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 KEY67206.1 - 0.048 13.3 0.0 0.095 12.3 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 KEY67206.1 - 0.06 13.4 0.0 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 KEY67206.1 - 0.067 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KEY67206.1 - 0.074 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 KEY67206.1 - 0.075 12.4 0.2 0.25 10.7 0.0 2.0 2 0 0 2 2 1 0 AAA-like domain NB-ARC PF00931.17 KEY67206.1 - 0.079 11.8 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.12 KEY67206.1 - 0.083 12.2 0.0 0.94 8.8 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein MobB PF03205.9 KEY67206.1 - 0.088 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activat PF00158.21 KEY67206.1 - 0.13 11.7 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.10 KEY67206.1 - 0.14 11.8 0.1 0.51 10.0 0.0 1.9 2 0 0 2 2 2 0 NTPase YjeF_N PF03853.10 KEY67207.1 - 1.1e-36 126.0 0.0 1.6e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 KEY67207.1 - 8.3e-11 42.3 0.8 8.3e-11 42.3 0.5 2.3 3 0 0 3 3 3 1 FDF domain PalH PF08733.5 KEY67208.1 - 2.5e-102 342.2 0.4 3.1e-102 341.9 0.3 1.1 1 0 0 1 1 1 1 PalH/RIM21 TRAM_LAG1_CLN8 PF03798.11 KEY67209.1 - 1.7e-35 122.3 20.1 2.7e-35 121.7 13.9 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 KEY67209.1 - 2.1e-23 81.5 0.0 2.1e-23 81.5 0.0 2.0 2 0 0 2 2 2 1 TRAM1-like protein Nucleoplasmin PF03066.10 KEY67209.1 - 0.00084 18.8 1.4 0.0013 18.2 1.0 1.2 1 0 0 1 1 1 1 Nucleoplasmin BSP_II PF05432.6 KEY67209.1 - 2 7.6 17.2 0.11 11.7 8.1 1.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) p450 PF00067.17 KEY67210.1 - 1.4e-54 185.3 0.0 1.9e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cortexin PF11057.3 KEY67210.1 - 0.067 12.7 0.3 0.15 11.7 0.2 1.5 1 0 0 1 1 1 0 Cortexin of kidney Tri3 PF07428.6 KEY67211.1 - 7.8e-58 196.1 0.0 1e-57 195.7 0.0 1.1 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 ketoacyl-synt PF00109.21 KEY67212.1 - 7.5e-71 238.5 0.0 1.4e-70 237.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEY67212.1 - 1.4e-52 178.9 0.0 2.8e-52 178.0 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KEY67212.1 - 5.7e-46 156.4 0.3 3.1e-45 154.0 0.1 2.3 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 KEY67212.1 - 2.7e-44 151.5 0.6 4e-44 150.9 0.1 1.5 2 0 0 2 2 2 1 Polyketide synthase dehydratase adh_short PF00106.20 KEY67212.1 - 5.5e-38 130.5 0.9 2.1e-37 128.6 0.6 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KEY67212.1 - 3.6e-36 123.5 2.2 4.8e-36 123.2 0.0 2.5 3 0 0 3 3 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KEY67212.1 - 6.4e-10 39.1 0.2 1.5e-09 37.9 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 KEY67212.1 - 8e-08 32.1 0.0 1.3e-06 28.2 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY67212.1 - 3.3e-05 24.2 0.2 0.00017 22.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY67212.1 - 0.00039 20.0 1.1 0.0039 16.7 0.1 2.8 3 0 0 3 3 3 1 Methyltransferase domain 3Beta_HSD PF01073.14 KEY67212.1 - 0.00072 18.3 0.1 0.0015 17.3 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.1 KEY67212.1 - 0.0015 18.3 0.0 0.015 15.1 0.0 2.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.7 KEY67212.1 - 0.0023 17.6 0.0 0.0064 16.2 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 KEY67212.1 - 0.0049 17.3 0.1 0.025 15.0 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KEY67212.1 - 0.016 14.7 0.0 0.047 13.2 0.0 1.9 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Acetyltransf_8 PF13523.1 KEY67213.1 - 3.6e-37 127.5 0.2 5.3e-37 127.0 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KEY67213.1 - 0.006 16.7 0.1 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Tri3 PF07428.6 KEY67215.1 - 4.2e-36 124.5 0.1 5e-36 124.3 0.1 1.0 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 DnaB_2 PF07261.6 KEY67215.1 - 0.038 13.6 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Replication initiation and membrane attachment DUF1833 PF08875.6 KEY67215.1 - 0.091 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) HLH PF00010.21 KEY67217.1 - 7.9e-13 47.8 0.2 1.7e-12 46.8 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CLTH PF10607.4 KEY67218.1 - 5e-31 107.3 0.0 8e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KEY67218.1 - 0.0032 17.1 0.6 0.014 15.1 0.0 2.4 3 0 0 3 3 3 1 LisH RecX PF02631.11 KEY67218.1 - 0.09 12.9 0.5 17 5.6 0.0 2.7 3 0 0 3 3 3 0 RecX family CAF1 PF04857.15 KEY67219.1 - 2.7e-67 226.8 0.0 3.4e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease RFX_DNA_binding PF02257.10 KEY67219.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain NDUF_B12 PF08122.7 KEY67220.1 - 1.8e-16 59.5 0.5 3e-16 58.8 0.3 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family ThiF PF00899.16 KEY67223.1 - 1.6e-17 63.5 0.0 2.5e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 ThiF family DUF2431 PF10354.4 KEY67225.1 - 3.6e-50 170.1 0.0 4.4e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Methyltransf_26 PF13659.1 KEY67225.1 - 0.0005 20.0 0.0 0.00069 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain SRI PF08236.6 KEY67226.1 - 7e-22 77.1 3.2 1.7e-21 75.9 2.2 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 KEY67226.1 - 1.3e-21 77.5 0.1 1.3e-21 77.5 0.1 3.7 3 2 0 3 3 3 1 SET domain Med26 PF08711.6 KEY67226.1 - 1.9e-05 24.0 0.2 4.9e-05 22.7 0.2 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain WW PF00397.21 KEY67226.1 - 0.00021 21.0 1.3 0.00031 20.5 0.2 1.9 2 0 0 2 2 2 1 WW domain Aminotran_3 PF00202.16 KEY67228.1 - 2.2e-99 332.5 0.0 2.7e-99 332.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KEY67228.1 - 0.055 12.4 0.0 0.081 11.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Voltage_CLC PF00654.15 KEY67229.1 - 4.6e-92 308.7 26.8 4.8e-92 308.7 16.7 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel TAT_signal PF10518.4 KEY67229.1 - 0.013 15.4 3.4 0.013 15.4 2.4 2.8 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence Sas10 PF09368.5 KEY67230.1 - 4.4e-29 100.4 7.0 4.4e-29 100.4 4.9 2.3 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 KEY67230.1 - 5e-12 45.8 0.0 2.6e-11 43.5 0.0 2.3 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Vps51 PF08700.6 KEY67231.1 - 1.8e-13 50.1 0.0 1.1e-12 47.6 0.0 2.4 2 0 0 2 2 2 1 Vps51/Vps67 ECH PF00378.15 KEY67232.1 - 3.6e-23 81.9 0.0 4.1e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family RNA_pol_I_A49 PF06870.7 KEY67233.1 - 2.2e-75 253.6 0.2 2.6e-75 253.4 0.2 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Pkinase PF00069.20 KEY67234.1 - 2.8e-55 187.2 0.0 3.8e-55 186.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY67234.1 - 3.7e-27 95.0 0.0 5.4e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KEY67234.1 - 6.1e-12 45.4 0.1 1.3e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KEY67234.1 - 4.3e-06 25.8 0.0 8.1e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEY67234.1 - 0.00036 19.6 0.0 0.0008 18.5 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Zeta_toxin PF06414.7 KEY67235.1 - 2.6e-44 150.7 0.0 3.7e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 KEY67235.1 - 3.5e-08 33.4 0.0 6.7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 KEY67235.1 - 0.0024 17.5 0.0 0.005 16.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 KEY67235.1 - 0.0027 17.7 0.9 0.0055 16.7 0.0 1.9 1 1 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 KEY67235.1 - 0.0047 16.6 0.0 0.0096 15.6 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 KEY67235.1 - 0.024 13.2 0.0 0.033 12.8 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.17 KEY67235.1 - 0.05 13.0 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 KEY67235.1 - 0.061 13.4 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KEY67235.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Zn_clus PF00172.13 KEY67236.1 - 0.0042 16.9 7.2 0.007 16.2 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3543 PF12063.3 KEY67237.1 - 3.1e-88 295.0 0.1 5.8e-88 294.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 KEY67237.1 - 3.1e-60 203.5 0.0 5.4e-60 202.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY67237.1 - 1.5e-41 142.1 0.0 2.8e-41 141.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3398 PF11878.3 KEY67237.1 - 0.096 12.5 0.0 0.8 9.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3398) Pox_ser-thr_kin PF05445.6 KEY67237.1 - 0.19 10.5 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Aminotran_3 PF00202.16 KEY67238.1 - 4.7e-96 321.5 0.0 3e-65 220.2 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-III Beta_elim_lyase PF01212.16 KEY67238.1 - 0.0002 20.6 0.0 0.00037 19.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Glyco_transf_22 PF03901.12 KEY67239.1 - 1.2e-78 264.9 22.5 1.5e-78 264.6 15.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family LigD_N PF13298.1 KEY67239.1 - 0.014 15.5 0.1 0.026 14.6 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase Ligase (LigD) RhoGAP PF00620.22 KEY67240.1 - 7.6e-37 126.2 0.0 1.3e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain zf-Tim10_DDP PF02953.10 KEY67241.1 - 5.6e-20 70.4 1.7 8.3e-20 69.8 1.2 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger KxDL PF10241.4 KEY67241.1 - 0.0071 16.2 2.2 1.7 8.6 0.1 2.1 1 1 1 2 2 2 2 Uncharacterized conserved protein Thionin PF00321.12 KEY67241.1 - 0.041 14.0 0.9 0.062 13.5 0.6 1.3 1 0 0 1 1 1 0 Plant thionin DUF3793 PF12672.2 KEY67241.1 - 0.05 13.1 0.0 0.089 12.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3793) Nup188 PF10487.4 KEY67242.1 - 1.2e-19 69.8 0.4 9.9e-19 66.8 0.2 2.1 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 IGPS PF00218.16 KEY67243.1 - 9.8e-95 316.4 0.0 1.4e-94 315.9 0.0 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 KEY67243.1 - 7.4e-50 169.0 0.1 2.2e-49 167.5 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I PRAI PF00697.17 KEY67243.1 - 2.4e-49 167.5 0.2 5.8e-46 156.5 0.0 2.8 2 1 1 3 3 3 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.8 KEY67243.1 - 3.3e-06 26.7 0.2 8.5e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase C26 QRPTase_C PF01729.14 KEY67243.1 - 0.001 18.6 0.3 0.088 12.3 0.1 2.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain FMN_dh PF01070.13 KEY67243.1 - 0.019 13.8 0.5 0.04 12.7 0.0 1.7 2 0 0 2 2 2 0 FMN-dependent dehydrogenase PTCB-BRCT PF12738.2 KEY67244.1 - 0.00052 19.8 0.2 0.001 18.8 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KEY67244.1 - 0.076 13.1 0.0 0.29 11.3 0.0 1.9 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Use1 PF09753.4 KEY67245.1 - 6.1e-08 32.4 0.0 9.2e-08 31.8 0.0 1.4 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF605 PF04652.11 KEY67245.1 - 0.089 12.1 13.3 0.12 11.7 9.2 1.2 1 0 0 1 1 1 0 Vta1 like Trypan_PARP PF05887.6 KEY67245.1 - 0.31 10.8 7.2 0.54 10.0 5.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) cwf21 PF08312.7 KEY67246.1 - 3.8e-18 65.0 15.2 3.8e-18 65.0 10.5 2.2 2 0 0 2 2 2 1 cwf21 domain GvpG PF05120.7 KEY67246.1 - 8 6.3 9.1 11 5.8 0.7 2.4 2 1 0 2 2 2 0 Gas vesicle protein G D123 PF07065.9 KEY67247.1 - 2.4e-88 296.1 0.0 3.8e-88 295.4 0.0 1.3 1 1 0 1 1 1 1 D123 DUF3470 PF11953.3 KEY67247.1 - 0.059 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3470) DUF3716 PF12511.3 KEY67248.1 - 4.1e-15 55.1 8.2 6.7e-15 54.4 5.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) G-alpha PF00503.15 KEY67249.1 - 9e-131 436.1 2.8 1.1e-130 435.8 1.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KEY67249.1 - 6.5e-13 48.2 1.2 2.4e-10 39.9 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 KEY67249.1 - 0.0008 18.9 0.0 0.0034 16.8 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 KEY67249.1 - 0.028 14.9 1.0 3.6 8.1 0.0 2.9 2 2 0 2 2 2 0 Miro-like protein KTI12 PF08433.5 KEY67250.1 - 7.7e-71 238.4 0.0 1.4e-70 237.6 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 DUF1771 PF08590.5 KEY67250.1 - 2.5e-22 78.6 5.2 2.5e-22 78.6 3.6 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.16 KEY67250.1 - 5.5e-15 55.3 1.0 4.1e-14 52.5 0.3 2.9 4 0 0 4 4 4 1 Smr domain AAA_17 PF13207.1 KEY67250.1 - 4.8e-05 24.1 2.2 0.00061 20.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KEY67250.1 - 7e-05 22.7 0.2 0.0003 20.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEY67250.1 - 0.0049 17.1 0.0 0.027 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KEY67250.1 - 0.0083 16.0 0.0 0.024 14.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain 6PF2K PF01591.13 KEY67250.1 - 0.029 13.4 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_16 PF13191.1 KEY67250.1 - 0.032 14.1 0.8 0.26 11.2 0.0 2.7 3 1 0 3 3 3 0 AAA ATPase domain AAA PF00004.24 KEY67251.1 - 1.7e-98 325.9 0.0 8.9e-48 161.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KEY67251.1 - 1.4e-19 69.7 0.4 5.7e-19 67.8 0.3 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 KEY67251.1 - 5.4e-14 51.8 0.0 3.4e-06 26.2 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 KEY67251.1 - 7.6e-14 51.9 0.0 1.8e-07 31.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KEY67251.1 - 5.8e-13 48.7 0.5 9.1e-07 28.6 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KEY67251.1 - 1.3e-12 47.8 0.0 1.5e-05 24.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 KEY67251.1 - 3.3e-12 46.6 0.3 0.00066 19.8 0.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEY67251.1 - 7.2e-12 45.6 0.0 0.00029 20.8 0.0 3.7 2 2 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 KEY67251.1 - 4.1e-11 43.7 0.0 0.00032 21.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 KEY67251.1 - 2.9e-09 36.1 0.1 0.00085 18.1 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 KEY67251.1 - 4.2e-09 36.0 5.1 0.017 14.5 0.0 4.5 2 2 2 4 4 4 3 AAA domain AAA_14 PF13173.1 KEY67251.1 - 2.9e-08 33.6 0.0 0.0014 18.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KEY67251.1 - 3.1e-08 33.2 0.0 0.0052 16.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 KEY67251.1 - 4.7e-08 32.6 2.2 0.0082 15.8 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain Zeta_toxin PF06414.7 KEY67251.1 - 6.2e-08 31.9 0.1 0.011 14.8 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin Mg_chelatase PF01078.16 KEY67251.1 - 1.6e-07 30.7 0.2 0.0056 15.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.12 KEY67251.1 - 2.6e-07 30.1 0.0 6.5e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 RNA_helicase PF00910.17 KEY67251.1 - 4.6e-07 29.9 0.0 0.026 14.7 0.0 2.9 3 0 0 3 3 2 2 RNA helicase KaiC PF06745.8 KEY67251.1 - 4.8e-07 29.1 0.6 0.22 10.6 0.0 3.5 2 1 1 3 3 3 2 KaiC AAA_18 PF13238.1 KEY67251.1 - 1.5e-06 28.5 0.0 0.085 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 KEY67251.1 - 1.9e-06 27.5 0.2 0.094 12.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.8 KEY67251.1 - 2.2e-06 26.7 0.0 0.0069 15.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) ResIII PF04851.10 KEY67251.1 - 2.4e-06 27.5 0.0 0.0021 17.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 KEY67251.1 - 3.1e-06 27.2 0.0 0.088 12.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 KEY67251.1 - 7.2e-06 25.8 0.0 2.5 7.7 0.0 3.9 2 2 1 3 3 3 1 Archaeal ATPase Parvo_NS1 PF01057.12 KEY67251.1 - 7.5e-06 24.9 0.1 0.043 12.6 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 KEY67251.1 - 9.6e-06 25.6 0.0 0.044 13.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 KEY67251.1 - 1.4e-05 24.6 0.1 0.16 11.4 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.13 KEY67251.1 - 1.5e-05 24.7 0.0 0.2 11.2 0.0 3.2 3 0 0 3 3 3 2 Bacterial dnaA protein NACHT PF05729.7 KEY67251.1 - 1.5e-05 24.7 0.0 0.084 12.5 0.0 3.3 3 0 0 3 3 3 1 NACHT domain ABC_tran PF00005.22 KEY67251.1 - 1.8e-05 25.0 0.0 0.23 11.7 0.0 3.5 2 1 0 2 2 2 2 ABC transporter Vps4_C PF09336.5 KEY67251.1 - 3.9e-05 23.4 0.2 0.00019 21.2 0.1 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain PhoH PF02562.11 KEY67251.1 - 0.00012 21.3 0.2 0.5 9.5 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 KEY67251.1 - 0.00013 21.5 0.0 0.56 9.8 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KEY67251.1 - 0.00018 21.1 0.0 0.49 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 KEY67251.1 - 0.00051 18.9 0.1 0.54 9.0 0.0 2.7 3 0 0 3 3 3 2 NB-ARC domain AAA_11 PF13086.1 KEY67251.1 - 0.00051 19.6 0.0 0.81 9.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.10 KEY67251.1 - 0.00067 19.4 0.3 0.64 9.7 0.0 3.9 3 0 0 3 3 3 1 NTPase DUF2075 PF09848.4 KEY67251.1 - 0.0015 17.5 0.0 1.5 7.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.9 KEY67251.1 - 0.0051 15.8 0.4 1 8.2 0.0 3.5 2 2 1 4 4 4 1 KAP family P-loop domain Viral_helicase1 PF01443.13 KEY67251.1 - 0.0064 16.0 0.0 0.28 10.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase IPT PF01745.11 KEY67251.1 - 0.01 15.0 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase UPF0079 PF02367.12 KEY67251.1 - 0.018 14.6 0.1 8.8 5.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 KEY67251.1 - 0.028 13.8 0.6 1.5 8.1 0.0 3.4 3 1 1 4 4 4 0 AAA-like domain T2SE PF00437.15 KEY67251.1 - 0.034 13.0 0.0 1.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Zot PF05707.7 KEY67251.1 - 0.048 13.1 0.4 12 5.2 0.1 3.8 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) AFG1_ATPase PF03969.11 KEY67251.1 - 0.071 11.9 0.0 8.7 5.0 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_23 PF13476.1 KEY67251.1 - 0.081 13.2 0.0 4.3 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 KEY67251.1 - 0.088 12.6 0.1 8.2 6.2 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase KTI12 PF08433.5 KEY67251.1 - 0.096 11.8 0.3 11 5.1 0.0 2.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 MobB PF03205.9 KEY67251.1 - 0.15 11.8 1.6 3.4 7.3 0.0 3.4 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B ERAP1_C PF11838.3 KEY67252.1 - 0.03 13.5 0.1 0.042 13.0 0.1 1.2 1 0 0 1 1 1 0 ERAP1-like C-terminal domain EnY2 PF10163.4 KEY67252.1 - 0.036 13.9 0.1 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 Transcription factor e(y)2 ABC_tran PF00005.22 KEY67254.1 - 1.3e-33 116.1 0.0 2.6e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KEY67254.1 - 2.2e-22 79.7 6.4 4e-22 78.9 3.0 2.4 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 KEY67254.1 - 5.6e-05 22.4 0.0 0.0007 18.8 0.0 1.8 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 KEY67254.1 - 0.0011 18.8 1.2 0.52 10.2 0.2 4.3 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 KEY67254.1 - 0.0026 16.9 0.0 0.0053 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 KEY67254.1 - 0.0054 16.7 0.0 5 7.0 0.0 3.2 2 1 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KEY67254.1 - 0.0089 15.5 0.0 0.78 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 KEY67254.1 - 0.011 15.2 0.1 0.03 13.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KEY67254.1 - 0.036 14.2 0.1 0.13 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain Ctr PF04145.10 KEY67254.1 - 0.29 11.1 4.8 15 5.6 0.1 3.8 4 0 0 4 4 4 0 Ctr copper transporter family Peptidase_M14 PF00246.19 KEY67255.1 - 9.9e-67 225.4 0.0 1.4e-66 224.9 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Git3 PF11710.3 KEY67256.1 - 1.9e-14 53.7 8.8 1.9e-14 53.7 6.1 2.0 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KEY67256.1 - 7.8e-11 41.5 6.4 7.8e-11 41.5 4.4 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 KEY67256.1 - 0.00042 19.3 6.8 0.00068 18.6 4.7 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3_C PF11970.3 KEY67256.1 - 0.0036 17.0 1.2 0.011 15.5 0.1 2.4 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term NPP1 PF05630.6 KEY67257.1 - 2e-74 249.7 1.7 2.4e-74 249.5 1.2 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) DUF946 PF06101.6 KEY67257.1 - 0.11 10.4 0.4 0.16 9.9 0.3 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF946) Aldedh PF00171.17 KEY67258.1 - 4.5e-152 506.6 0.0 5.3e-152 506.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.14 KEY67259.1 - 1.6e-53 181.7 0.0 2.3e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY67259.1 - 5.3e-41 140.2 0.0 8.2e-41 139.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KEY67259.1 - 2.1e-05 23.6 0.0 0.0022 16.9 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEY67259.1 - 3.2e-05 22.9 0.0 0.075 11.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KEY67259.1 - 0.00019 20.4 0.0 0.00029 19.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KEY67259.1 - 0.0013 18.7 0.1 0.0045 16.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KEY67259.1 - 0.088 11.4 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 KEY67259.1 - 0.089 13.2 0.0 0.74 10.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEY67259.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF903 PF06004.7 KEY67259.1 - 0.15 11.6 0.3 0.48 9.9 0.0 2.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF903) HI0933_like PF03486.9 KEY67259.1 - 0.23 9.8 0.0 0.48 8.8 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein DUF1479 PF07350.7 KEY67260.1 - 5.8e-143 476.3 0.0 7.8e-143 475.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Zip PF02535.17 KEY67260.1 - 0.0029 16.6 5.3 0.0062 15.5 3.7 1.5 1 0 0 1 1 1 1 ZIP Zinc transporter KIX PF02172.11 KEY67260.1 - 0.085 12.9 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 KIX domain AMP-binding PF00501.23 KEY67261.1 - 1.3e-255 847.3 0.0 6.6e-86 288.3 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KEY67261.1 - 1.9e-182 604.9 7.4 1.4e-33 116.0 0.0 7.7 6 2 1 7 7 7 7 Condensation domain PP-binding PF00550.20 KEY67261.1 - 4.9e-55 183.6 16.4 1.8e-10 40.8 0.0 7.1 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KEY67261.1 - 1.1e-19 71.1 0.0 4.8e-06 27.4 0.0 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Transferase PF02458.10 KEY67261.1 - 0.00024 19.7 0.5 16 3.7 0.0 4.8 5 0 0 5 5 5 2 Transferase family AATase PF07247.7 KEY67261.1 - 0.021 13.4 0.3 22 3.4 0.0 4.3 4 0 0 4 4 4 0 Alcohol acetyltransferase SWIB PF02201.13 KEY67261.1 - 0.24 11.0 0.1 0.58 9.8 0.1 1.7 1 0 0 1 1 1 0 SWIB/MDM2 domain K_oxygenase PF13434.1 KEY67262.1 - 9.6e-102 340.3 0.0 1.2e-101 340.0 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KEY67262.1 - 1.8e-10 41.2 0.0 1.4e-09 38.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEY67262.1 - 3.3e-07 30.1 0.0 1.3e-05 25.0 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KEY67262.1 - 7.4e-06 25.9 0.0 1.6e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF4147 PF13660.1 KEY67262.1 - 0.014 14.4 0.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) IF-2B PF01008.12 KEY67263.1 - 2.6e-21 75.8 0.0 4.1e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family Fungal_trans PF04082.13 KEY67263.1 - 5.8e-12 45.0 0.0 1.6e-11 43.5 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain NUDIX PF00293.23 KEY67263.1 - 6.4e-11 42.0 0.0 2.6e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain Zn_clus PF00172.13 KEY67263.1 - 8.8e-06 25.5 8.7 1.4e-05 24.8 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FF PF01846.14 KEY67264.1 - 4.5e-13 48.9 7.4 1.8e-08 34.1 0.1 2.9 3 0 0 3 3 3 2 FF domain WW PF00397.21 KEY67264.1 - 1.6e-08 34.2 0.5 3.8e-08 33.0 0.4 1.7 1 0 0 1 1 1 1 WW domain TTSSLRR PF12468.3 KEY67264.1 - 0.053 13.0 1.8 0.21 11.1 1.2 2.1 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein PAP2 PF01569.16 KEY67265.1 - 3.6e-24 84.8 1.2 7.5e-24 83.8 0.9 1.5 1 0 0 1 1 1 1 PAP2 superfamily TcpE PF12648.2 KEY67265.1 - 3.9 7.6 7.8 2.7 8.1 1.5 2.2 1 1 1 2 2 2 0 TcpE family VanZ PF04892.7 KEY67265.1 - 4.7 7.1 7.8 4.3 7.2 2.7 2.4 2 1 0 2 2 2 0 VanZ like family Proteasome PF00227.21 KEY67266.1 - 4.1e-61 205.6 0.1 4.9e-61 205.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEY67266.1 - 9.9e-15 53.5 0.2 6.9e-14 50.8 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 KEY67266.1 - 0.16 11.2 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Ferric_reduct PF01794.14 KEY67267.1 - 6.6e-17 61.7 13.2 1.3e-16 60.8 9.1 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KEY67267.1 - 1.3e-07 31.4 0.1 3e-07 30.2 0.1 1.6 1 1 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.1 KEY67267.1 - 0.02 15.0 10.9 0.41 10.8 0.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) Cytochrom_B_N PF00033.14 KEY67267.1 - 0.3 10.4 19.6 7.3 5.8 13.6 2.3 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Peptidase_C2 PF00648.16 KEY67269.1 - 9.8e-22 77.3 0.0 1.5e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 KEY67269.1 - 3.3e-14 52.7 0.0 2.8e-11 43.2 0.0 3.6 2 2 0 2 2 2 2 Calpain large subunit, domain III MIT PF04212.13 KEY67269.1 - 0.011 15.6 0.4 0.019 14.8 0.3 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Mito_carr PF00153.22 KEY67270.1 - 2.6e-54 180.9 1.6 1e-18 66.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L29e PF01779.12 KEY67271.1 - 1.6e-22 79.0 9.3 2.6e-22 78.4 6.4 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family SAM_2 PF07647.12 KEY67272.1 - 1.7e-10 40.5 0.1 3.2e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KEY67272.1 - 6.6e-06 26.2 0.2 1.4e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.5 KEY67272.1 - 0.17 11.8 0.1 0.42 10.5 0.1 1.6 1 0 0 1 1 1 0 IGR protein motif TPR_11 PF13414.1 KEY67273.1 - 2.2e-21 75.2 17.3 0.00037 20.0 1.7 7.2 6 1 1 7 7 7 6 TPR repeat TPR_16 PF13432.1 KEY67273.1 - 9.9e-16 57.9 19.4 3.2e-05 24.4 0.0 7.3 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 KEY67273.1 - 1e-13 51.4 10.4 0.0082 16.4 0.0 8.3 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEY67273.1 - 5.1e-13 48.3 22.3 0.023 15.2 0.1 10.0 7 3 3 10 10 9 4 Tetratricopeptide repeat TPR_2 PF07719.12 KEY67273.1 - 1.3e-11 43.4 19.3 0.21 11.5 0.0 10.0 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEY67273.1 - 3.6e-11 42.1 2.1 1.8 8.3 0.0 9.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEY67273.1 - 4.2e-11 42.1 2.3 1.8 8.9 0.0 7.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEY67273.1 - 1.4e-09 37.7 20.9 0.00048 19.9 0.0 6.9 6 2 1 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEY67273.1 - 1.8e-06 27.3 7.7 0.13 12.0 0.1 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_20 PF14561.1 KEY67273.1 - 2.5e-06 27.4 15.4 0.19 11.8 0.0 6.7 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEY67273.1 - 1e-05 24.9 3.2 0.09 12.6 0.0 5.9 8 0 0 8 8 7 1 Tetratricopeptide repeat Apc3 PF12895.2 KEY67273.1 - 0.0016 18.5 5.7 0.69 10.0 0.0 4.5 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KEY67273.1 - 0.01 15.7 3.1 0.01 15.7 2.1 6.0 6 1 1 7 7 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEY67273.1 - 0.032 14.6 12.3 2.8 8.5 0.1 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KEY67273.1 - 0.11 12.7 2.3 1.8 8.7 0.1 3.1 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation NARP1 PF12569.3 KEY67273.1 - 0.25 10.0 3.7 6.3 5.4 0.0 2.9 3 1 1 4 4 4 0 NMDA receptor-regulated protein 1 TPR_9 PF13371.1 KEY67273.1 - 0.27 11.1 12.6 1.1 9.1 0.4 5.3 3 2 2 5 5 5 0 Tetratricopeptide repeat Sad1_UNC PF07738.8 KEY67274.1 - 5.1e-36 123.4 0.0 8.1e-36 122.7 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Macoilin PF09726.4 KEY67274.1 - 0.29 9.3 13.5 0.036 12.3 6.4 1.6 2 0 0 2 2 2 0 Transmembrane protein Peptidase_S64 PF08192.6 KEY67274.1 - 2.8 6.1 6.2 4.5 5.4 4.3 1.3 1 0 0 1 1 1 0 Peptidase family S64 RRM_2 PF04059.7 KEY67275.1 - 2.1e-39 133.4 0.6 4.6e-39 132.3 0.2 1.7 2 0 0 2 2 2 1 RNA recognition motif 2 RRM_1 PF00076.17 KEY67275.1 - 0.0076 15.8 0.3 0.16 11.6 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY67275.1 - 0.065 13.2 0.1 1.8 8.6 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Sec15 PF04091.7 KEY67276.1 - 1.3e-115 386.0 3.4 1.3e-115 386.0 2.4 2.2 2 1 1 3 3 3 1 Exocyst complex subunit Sec15-like DUF4201 PF13870.1 KEY67276.1 - 0.0042 16.5 4.8 0.0058 16.0 2.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) CBFD_NFYB_HMF PF00808.18 KEY67277.1 - 1.3e-19 70.0 0.6 2.1e-19 69.3 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KEY67277.1 - 2.1e-12 46.9 0.1 3.8e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 KEY67277.1 - 0.021 14.6 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Fcf2 PF08698.6 KEY67278.1 - 8.4e-24 83.4 1.0 2.3e-23 82.0 0.7 1.7 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Ribosomal_S10 PF00338.17 KEY67279.1 - 5e-23 80.7 0.0 1.1e-22 79.6 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e tRNA-synt_1b PF00579.20 KEY67280.1 - 2.8e-54 184.2 0.0 1.8e-52 178.2 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.13 KEY67280.1 - 0.056 12.0 0.0 0.097 11.3 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Peptidase_M24 PF00557.19 KEY67282.1 - 4.7e-39 134.1 0.1 7.3e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KEY67282.1 - 8.5e-24 84.5 0.0 7.5e-20 71.7 0.0 2.6 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain DUF2659 PF10858.3 KEY67282.1 - 0.19 11.0 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2659) Histone PF00125.19 KEY67283.1 - 1.2e-28 98.9 0.4 1.7e-28 98.5 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KEY67283.1 - 0.00042 20.4 0.1 0.00061 19.9 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KEY67283.1 - 0.0055 16.7 0.0 0.0085 16.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KEY67283.1 - 0.0092 15.2 0.7 0.01 15.1 0.1 1.4 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KEY67283.1 - 0.022 14.5 0.1 0.042 13.6 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 KEY67283.1 - 0.065 12.9 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated DER1 PF04511.10 KEY67284.1 - 1.6e-49 168.1 3.2 1.8e-49 167.9 2.2 1.0 1 0 0 1 1 1 1 Der1-like family ARD PF03079.9 KEY67285.1 - 2.5e-46 157.5 0.1 2.9e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 KEY67285.1 - 3.5e-08 32.8 0.1 5.8e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KEY67285.1 - 3.1e-06 26.8 0.0 4.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 KEY67285.1 - 0.019 14.3 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Cupin adh_short PF00106.20 KEY67286.1 - 4.4e-21 75.4 0.0 8.1e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY67286.1 - 1.1e-11 44.7 0.0 1.8e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY67286.1 - 1.3e-07 31.3 0.1 2.2e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY67286.1 - 0.00011 22.2 0.0 0.0002 21.4 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEY67286.1 - 0.007 15.0 0.0 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KEY67286.1 - 0.015 14.2 0.0 0.03 13.1 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.8 KEY67286.1 - 0.051 12.8 0.1 0.1 11.8 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family UAA PF08449.6 KEY67287.1 - 1.8e-10 40.2 21.9 2.4e-10 39.8 15.2 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KEY67287.1 - 6.7e-09 35.5 9.8 6.7e-09 35.5 6.8 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KEY67287.1 - 0.0027 17.7 8.4 0.0027 17.7 5.8 2.4 2 0 0 2 2 2 1 EamA-like transporter family Spike_rec_bind PF09408.5 KEY67287.1 - 0.021 14.3 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Spike receptor binding domain Peptidase_A24 PF01478.13 KEY67287.1 - 0.045 13.9 0.3 0.045 13.9 0.2 3.7 2 2 1 3 3 3 0 Type IV leader peptidase family UPF0370 PF13980.1 KEY67287.1 - 0.06 13.1 0.1 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) MBOAT PF03062.14 KEY67288.1 - 2.4e-48 164.9 3.9 2.4e-48 164.9 2.7 1.8 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Abi PF02517.11 KEY67290.1 - 1.2e-12 47.8 9.7 1.2e-12 47.8 6.7 2.3 2 1 1 3 3 3 1 CAAX protease self-immunity DUF1635 PF07795.6 KEY67290.1 - 0.21 10.9 0.1 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF2404 PF10296.4 KEY67291.1 - 1.4e-08 34.7 0.0 2.5e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DUF1628 PF07790.6 KEY67291.1 - 0.016 15.9 0.0 0.032 14.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) Sec1 PF00995.18 KEY67292.1 - 1e-155 519.6 0.0 1.1e-155 519.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family HEAT_2 PF13646.1 KEY67292.1 - 0.067 13.4 0.1 4.3 7.6 0.0 2.8 2 0 0 2 2 2 0 HEAT repeats GIDA PF01134.17 KEY67293.1 - 3e-155 516.9 0.0 3.9e-155 516.5 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 KEY67293.1 - 1.2e-16 60.5 0.0 2.8e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 KEY67293.1 - 2.4e-08 34.1 0.6 5.8e-08 32.8 0.4 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEY67293.1 - 2.4e-07 30.2 0.6 3.9e-07 29.5 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 KEY67293.1 - 0.00025 20.0 2.9 0.15 10.9 0.8 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEY67293.1 - 0.00044 19.2 2.0 0.00044 19.2 1.4 2.4 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.1 KEY67293.1 - 0.0062 16.6 0.0 0.061 13.3 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEY67293.1 - 0.011 14.2 5.0 0.067 11.6 0.7 3.0 3 0 0 3 3 3 0 HI0933-like protein AlaDh_PNT_C PF01262.16 KEY67293.1 - 0.014 14.9 0.1 0.028 13.9 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 KEY67293.1 - 0.016 14.9 0.7 0.036 13.8 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 KEY67293.1 - 0.036 14.3 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.22 KEY67293.1 - 0.083 13.2 0.4 0.21 12.0 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KEY67293.1 - 0.11 11.0 0.3 13 4.2 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.7 KEY67293.1 - 0.17 10.7 1.7 4.7 6.0 0.5 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein CDP-OH_P_transf PF01066.16 KEY67294.1 - 1.8e-17 63.5 2.4 1.8e-17 63.5 1.7 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase WD40 PF00400.27 KEY67295.1 - 4.4e-71 232.4 14.6 2.4e-10 39.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 KEY67295.1 - 3e-23 81.8 9.7 4.8e-23 81.1 6.7 1.3 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 KEY67295.1 - 1.3e-05 23.5 4.4 0.0083 14.3 0.0 4.1 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KEY67295.1 - 0.00096 17.9 0.1 0.19 10.4 0.1 3.3 1 1 2 3 3 3 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 KEY67295.1 - 0.001 17.4 0.1 0.052 11.8 0.0 2.7 1 1 1 2 2 2 2 Cytochrome D1 heme domain zf-C4H2 PF10146.4 KEY67295.1 - 0.044 13.8 0.5 0.079 12.9 0.4 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein DUF2076 PF09849.4 KEY67295.1 - 0.063 13.3 6.8 0.13 12.3 4.7 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) LXG PF04740.7 KEY67295.1 - 0.067 12.9 3.3 0.11 12.3 2.3 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily Nbas_N PF15492.1 KEY67295.1 - 0.098 11.7 0.0 17 4.3 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal CAP_N PF01213.14 KEY67296.1 - 0.0096 15.2 5.1 0.01 15.1 2.8 1.6 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal OAD_gamma PF04277.8 KEY67296.1 - 5.8 7.3 6.1 8.4 6.8 0.1 2.3 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Aa_trans PF01490.13 KEY67297.1 - 5.1e-61 206.3 20.3 6.3e-61 206.0 14.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pkinase PF00069.20 KEY67298.1 - 2.7e-60 203.7 0.0 5e-60 202.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY67298.1 - 3.9e-35 121.1 0.0 5.7e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY67298.1 - 3.2e-15 55.8 0.0 1.1e-12 47.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 KEY67298.1 - 0.011 14.7 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HAD_2 PF13419.1 KEY67300.1 - 1.3e-24 87.3 0.0 1.7e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF3321 PF11968.3 KEY67301.1 - 7.8e-84 280.7 0.0 1.2e-83 280.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 KEY67301.1 - 0.00088 19.0 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ribosomal_L23eN PF03939.8 KEY67302.1 - 1.5e-20 72.9 9.5 1.5e-20 72.9 6.6 2.3 2 2 1 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 KEY67302.1 - 8.4e-18 64.1 2.3 1.6e-17 63.2 1.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 zf-Tim10_DDP PF02953.10 KEY67303.1 - 1.7e-18 65.6 3.3 2.2e-18 65.3 2.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger SieB PF14163.1 KEY67303.1 - 0.049 13.2 0.0 0.056 13.0 0.0 1.1 1 0 0 1 1 1 0 Superinfection exclusion protein B Tyr-DNA_phospho PF06087.7 KEY67304.1 - 2.2e-67 227.6 0.0 2.7e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 KEY67304.1 - 0.00057 19.6 0.0 0.0023 17.6 0.0 2.1 2 0 0 2 2 2 1 PLD-like domain UIM PF02809.15 KEY67304.1 - 0.0025 17.2 4.7 0.0057 16.1 3.3 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif Gti1_Pac2 PF09729.4 KEY67305.1 - 5.5e-61 205.2 0.0 7.6e-61 204.8 0.0 1.2 1 0 0 1 1 1 1 Gti1/Pac2 family DsbB PF02600.11 KEY67305.1 - 0.17 11.6 0.6 0.26 11.0 0.4 1.2 1 0 0 1 1 1 0 Disulfide bond formation protein DsbB DUF2015 PF09435.5 KEY67306.1 - 4.8e-45 152.4 0.0 5.4e-45 152.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) CcoS PF03597.10 KEY67306.1 - 2.3 7.7 4.1 4.1 6.9 2.8 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Ribosomal_L28e PF01778.12 KEY67307.1 - 5.1e-38 130.0 0.5 6.4e-38 129.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_C PF02866.13 KEY67308.1 - 1.6e-42 145.2 0.0 2.6e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 KEY67308.1 - 2.3e-42 144.1 0.2 3.2e-42 143.6 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KEY67308.1 - 0.00027 19.7 0.0 0.00037 19.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KEY67308.1 - 0.025 14.9 0.0 0.054 13.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.11 KEY67308.1 - 0.085 12.1 0.2 6.2 6.0 0.1 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase TRAPP PF04051.11 KEY67309.1 - 3.3e-39 133.8 0.0 4.3e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF2246 PF10229.4 KEY67309.1 - 0.0021 17.4 0.0 0.0027 17.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2246) PINIT PF14324.1 KEY67310.1 - 1.1e-37 129.2 0.0 2.4e-37 128.2 0.0 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KEY67310.1 - 3.5e-20 71.2 9.1 6e-20 70.5 6.3 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KEY67310.1 - 3.4e-05 23.2 3.1 7.1e-05 22.2 2.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 KEY67310.1 - 9.6e-05 21.7 0.0 0.0002 20.7 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-Sec23_Sec24 PF04810.10 KEY67310.1 - 0.0084 15.6 0.1 0.029 13.9 0.0 1.9 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger TFIIF_alpha PF05793.7 KEY67310.1 - 0.24 9.7 2.2 0.43 8.8 1.5 1.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-C3HC4_4 PF15227.1 KEY67310.1 - 1.1 9.2 9.0 2.5 8.0 6.3 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KEY67310.1 - 2.7 7.7 6.9 5.4 6.8 4.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain CorA PF01544.13 KEY67311.1 - 5.1e-45 153.7 0.0 8.6e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SPC12 PF06645.8 KEY67312.1 - 2.5e-25 88.1 0.1 2.9e-25 87.8 0.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF3040 PF11239.3 KEY67312.1 - 0.056 13.4 0.5 0.067 13.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) zf-rbx1 PF12678.2 KEY67313.1 - 2.4e-32 110.8 13.3 3.3e-32 110.4 9.3 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KEY67313.1 - 9.7e-16 57.3 9.9 1.4e-15 56.8 6.9 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KEY67313.1 - 2.5e-06 27.2 13.6 2.6e-05 23.9 9.4 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KEY67313.1 - 0.0016 18.0 11.7 0.053 13.1 8.1 2.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEY67313.1 - 0.005 16.8 3.3 0.005 16.8 2.3 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEY67313.1 - 0.014 15.0 10.3 1.4 8.6 7.3 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY67313.1 - 1.1 9.0 11.6 8.9 6.1 8.0 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 KEY67313.1 - 1.9 8.3 6.8 50 3.7 4.7 2.4 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 KEY67313.1 - 1.9 8.5 9.6 12 5.9 6.8 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain PNRC PF15365.1 KEY67314.1 - 0.00014 21.8 8.5 0.00014 21.8 5.9 4.9 5 1 0 5 5 5 2 Proline-rich nuclear receptor coactivator Phosphodiest PF01663.17 KEY67315.1 - 4e-16 59.3 0.3 1.7e-14 53.9 0.2 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KEY67315.1 - 0.00016 20.9 0.0 0.00028 20.1 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 KEY67315.1 - 0.00066 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Cnd3 PF12719.2 KEY67316.1 - 1.9e-88 296.3 1.1 1.9e-88 296.3 0.7 2.4 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 KEY67316.1 - 1.7e-11 44.2 14.3 2.1e-06 27.8 1.0 5.6 4 2 1 5 5 5 4 HEAT repeats HEAT PF02985.17 KEY67316.1 - 1.9e-06 27.4 9.7 0.15 12.1 0.0 7.0 7 0 0 7 7 7 2 HEAT repeat DUF1546 PF07571.8 KEY67316.1 - 0.041 14.0 0.3 0.69 10.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) HEAT_EZ PF13513.1 KEY67316.1 - 5.7 7.5 26.7 0.068 13.6 1.3 7.0 5 1 3 8 8 8 0 HEAT-like repeat RRM_1 PF00076.17 KEY67317.1 - 3.8e-61 202.6 1.1 1.9e-19 69.0 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY67317.1 - 3.5e-48 161.4 0.1 2.7e-16 59.2 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY67317.1 - 2.3e-21 75.4 0.3 8.3e-07 28.7 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 KEY67317.1 - 0.071 12.7 0.0 7.5 6.2 0.0 2.6 2 0 0 2 2 2 0 DbpA RNA binding domain Mg_trans_NIPA PF05653.9 KEY67319.1 - 1.1e-60 205.1 3.6 2.6e-57 194.0 1.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 KEY67319.1 - 8.9e-05 22.6 0.5 8.9e-05 22.6 0.3 3.8 3 1 1 4 4 4 2 Multidrug resistance efflux transporter EamA PF00892.15 KEY67319.1 - 0.0032 17.5 1.8 0.0032 17.5 1.3 4.1 3 1 0 4 4 4 2 EamA-like transporter family DUF914 PF06027.7 KEY67319.1 - 0.0048 15.7 3.3 0.037 12.8 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) Vezatin PF12632.2 KEY67319.1 - 0.41 9.6 0.4 1.5 7.8 0.0 1.9 2 0 0 2 2 2 0 Mysoin-binding motif of peroxisomes PBD PF00786.23 KEY67321.1 - 0.011 16.0 2.3 0.034 14.5 0.4 2.8 2 0 0 2 2 2 0 P21-Rho-binding domain SSrecog PF03531.9 KEY67322.1 - 4.1e-73 245.3 0.1 5.7e-72 241.6 0.1 2.4 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KEY67322.1 - 7e-24 83.6 0.0 4.3e-23 81.0 0.0 2.3 3 0 0 3 3 3 1 Histone chaperone Rttp106-like DUF2201_N PF13203.1 KEY67322.1 - 8.8 5.4 8.7 2.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain Lipase_3 PF01764.20 KEY67323.1 - 6.9e-06 25.7 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KEY67323.1 - 0.0062 16.2 0.2 0.02 14.6 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY67323.1 - 0.0094 15.8 0.2 0.023 14.5 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family UPF0227 PF05728.7 KEY67323.1 - 0.033 13.8 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) YL1 PF05764.8 KEY67324.1 - 7e-58 196.0 26.3 7e-58 196.0 18.3 3.1 3 0 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 KEY67324.1 - 3.9e-15 55.0 1.6 7.9e-15 54.1 1.1 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-HIT PF04438.11 KEY67324.1 - 0.037 13.6 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 HIT zinc finger HTH_Tnp_IS630 PF01710.11 KEY67324.1 - 8.3 6.1 9.2 3.9 7.1 1.5 2.5 2 0 0 2 2 2 0 Transposase FA_hydroxylase PF04116.8 KEY67326.1 - 8.6e-19 68.0 12.5 1.9e-18 66.8 6.5 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TCTP PF00838.12 KEY67327.1 - 2.1e-67 226.2 1.5 2.3e-67 226.0 1.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Mis12 PF05859.7 KEY67329.1 - 2.6e-33 114.8 0.0 4.2e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein ENT PF03735.9 KEY67329.1 - 0.08 12.6 0.7 0.17 11.5 0.1 1.8 2 0 0 2 2 2 0 ENT domain PPR_2 PF13041.1 KEY67330.1 - 4.2e-22 77.8 0.0 4.6e-05 23.2 0.0 7.1 6 1 1 7 7 7 5 PPR repeat family PPR_3 PF13812.1 KEY67330.1 - 4.4e-14 51.4 0.1 0.57 10.6 0.0 8.7 9 0 0 9 9 9 3 Pentatricopeptide repeat domain PPR PF01535.15 KEY67330.1 - 7.4e-11 41.2 0.0 0.057 13.4 0.0 5.8 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.2 KEY67330.1 - 1.7e-07 30.5 0.0 0.45 10.0 0.0 4.6 4 0 0 4 4 4 3 PPR repeat RPM2 PF08579.6 KEY67330.1 - 6.9e-05 22.9 0.0 0.088 12.9 0.0 4.1 5 1 0 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) DUF832 PF05734.6 KEY67330.1 - 0.0083 15.3 0.1 0.021 14.0 0.0 1.6 1 0 0 1 1 1 1 Herpesvirus protein of unknown function (DUF832) GST_N PF02798.15 KEY67331.1 - 1.6e-08 34.5 0.0 4e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KEY67331.1 - 5.6e-07 29.7 0.0 1.2e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KEY67331.1 - 1e-05 25.4 0.0 2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KEY67331.1 - 1.6e-05 24.7 0.0 6.2e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KEY67331.1 - 2.5e-05 24.6 0.0 4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KEY67331.1 - 0.0024 17.7 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Alg6_Alg8 PF03155.10 KEY67332.1 - 1.7e-141 472.3 26.9 2.4e-141 471.7 18.7 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WAC_Acf1_DNA_bd PF10537.4 KEY67332.1 - 7.2e-37 125.6 2.4 1.5e-36 124.6 0.0 2.7 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 KEY67332.1 - 1.4e-15 56.8 1.5 2.6e-15 55.9 1.1 1.5 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 KEY67332.1 - 1.6e-12 46.7 0.3 3.8e-12 45.6 0.2 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 KEY67332.1 - 0.00033 20.3 0.1 0.00083 19.0 0.1 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM1 PF15612.1 KEY67332.1 - 0.011 15.5 0.1 0.032 14.1 0.1 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Lectin_leg-like PF03388.8 KEY67333.1 - 7.4e-25 87.4 0.0 2e-24 86.0 0.0 1.6 2 0 0 2 2 2 1 Legume-like lectin family BLOC1_2 PF10046.4 KEY67333.1 - 0.048 13.7 5.5 0.09 12.9 3.8 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.7 KEY67333.1 - 0.068 12.9 4.1 0.24 11.1 2.8 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HisKA_3 PF07730.8 KEY67333.1 - 0.17 12.2 0.6 0.42 11.0 0.2 1.9 1 1 0 1 1 1 0 Histidine kinase Phage_GPO PF05929.6 KEY67333.1 - 0.19 10.9 7.3 0.12 11.5 3.9 1.4 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase FliT PF05400.8 KEY67333.1 - 0.43 11.0 5.1 13 6.2 2.2 2.8 1 1 1 2 2 2 0 Flagellar protein FliT DUF1319 PF07028.6 KEY67333.1 - 0.46 10.6 9.8 0.084 13.0 4.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) LUC7 PF03194.10 KEY67333.1 - 0.9 9.0 11.6 0.54 9.7 6.5 1.5 1 1 1 2 2 2 0 LUC7 N_terminus BRE1 PF08647.6 KEY67333.1 - 1.3 9.0 12.2 0.17 11.8 5.1 1.9 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase V_ATPase_I PF01496.14 KEY67333.1 - 3.5 5.3 7.5 5.4 4.7 5.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.8 KEY67333.1 - 7.3 5.5 8.7 4 6.4 4.7 1.5 1 1 0 1 1 1 0 TMPIT-like protein Peptidase_M24 PF00557.19 KEY67334.1 - 1.4e-57 194.6 0.1 1.8e-57 194.2 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KEY67334.1 - 1.2e-19 70.0 0.0 2.1e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Fungal_trans PF04082.13 KEY67335.1 - 3.8e-31 107.8 0.1 6.4e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY67335.1 - 7.7e-11 41.7 13.6 1.5e-10 40.7 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEY67335.1 - 0.0077 14.8 0.0 0.0077 14.8 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain RPN7 PF10602.4 KEY67336.1 - 1.6e-49 167.7 0.0 2.5e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KEY67336.1 - 1.2e-17 64.1 0.1 6.3e-17 61.8 0.0 2.1 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.12 KEY67336.1 - 0.0045 16.7 0.2 21 5.3 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat Prp18 PF02840.10 KEY67337.1 - 4.3e-52 175.7 0.0 4.3e-52 175.7 0.0 1.8 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 KEY67337.1 - 1.2e-11 43.6 1.6 1.2e-11 43.6 1.1 2.7 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like CDC27 PF09507.5 KEY67337.1 - 0.12 11.6 14.7 0.19 10.8 10.2 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Borrelia_P83 PF05262.6 KEY67337.1 - 1.7 6.8 13.3 2.3 6.3 9.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Ycf1 PF05758.7 KEY67337.1 - 3.2 5.3 5.5 3.5 5.2 3.8 1.1 1 0 0 1 1 1 0 Ycf1 NDUF_B4 PF07225.7 KEY67338.1 - 0.13 12.0 0.1 0.14 11.9 0.1 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) PspC PF04024.7 KEY67338.1 - 0.3 10.6 1.4 0.42 10.1 1.0 1.2 1 0 0 1 1 1 0 PspC domain PROCN PF08083.6 KEY67339.1 - 3.1e-221 734.0 8.1 5.1e-221 733.3 5.6 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 KEY67339.1 - 6.2e-125 415.0 1.3 1.1e-124 414.2 0.9 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 KEY67339.1 - 1.3e-94 313.8 0.6 4.8e-60 201.5 0.1 2.6 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 KEY67339.1 - 5.3e-76 253.4 3.7 9.7e-76 252.5 1.8 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 KEY67339.1 - 2.8e-66 221.2 0.0 6.1e-66 220.1 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 Hom_end_hint PF05203.11 KEY67339.1 - 5.6e-47 160.2 6.8 1.9e-28 99.6 0.0 3.3 2 1 1 3 3 3 2 Hom_end-associated Hint RRM_4 PF10598.4 KEY67339.1 - 9.6e-44 147.1 0.1 9.2e-43 144.0 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 KEY67339.1 - 4.1e-40 136.3 0.2 1.3e-39 134.7 0.0 2.0 2 0 0 2 2 2 1 PROCT (NUC072) domain JAB PF01398.16 KEY67339.1 - 0.0032 17.1 0.0 0.025 14.3 0.0 2.4 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Hint_2 PF13403.1 KEY67339.1 - 0.023 14.6 0.0 0.061 13.2 0.0 1.8 1 1 0 1 1 1 0 Hint domain DUF3753 PF12575.3 KEY67339.1 - 0.094 12.5 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Cyt-b5 PF00173.23 KEY67340.1 - 6.5e-11 41.8 0.0 8.1e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CytB6-F_Fe-S PF08802.5 KEY67340.1 - 0.07 13.1 0.5 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit TFR_dimer PF04253.10 KEY67341.1 - 4.3e-25 87.6 0.1 6.8e-25 87.0 0.1 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KEY67341.1 - 2.6e-12 46.8 0.0 5.3e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KEY67341.1 - 3.1e-07 30.0 0.2 6.6e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 PA domain Vps35 PF03635.12 KEY67342.1 - 0 1020.8 0.2 0 1020.7 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Xpo1 PF08389.7 KEY67342.1 - 0.12 12.3 0.9 1.6 8.6 0.0 3.1 3 1 0 3 3 3 0 Exportin 1-like protein Tim44 PF04280.10 KEY67343.1 - 3.1e-32 111.5 0.1 2.2e-31 108.8 0.0 2.4 2 0 0 2 2 2 1 Tim44-like domain DndB PF14072.1 KEY67343.1 - 0.037 13.1 0.0 0.11 11.6 0.0 1.7 1 0 0 1 1 1 0 DNA-sulfur modification-associated Ribosomal_S11 PF00411.14 KEY67344.1 - 9.1e-09 35.4 0.0 1.6e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S11 CDC48_N PF02359.13 KEY67344.1 - 0.045 13.6 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain DUF4160 PF13711.1 KEY67344.1 - 0.13 12.0 0.5 0.26 11.1 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) Peptidase_C97 PF05903.9 KEY67345.1 - 5.7e-33 113.8 0.0 7e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 KEY67345.1 - 0.0055 16.6 0.0 0.0085 16.0 0.0 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase YchF-GTPase_C PF06071.8 KEY67346.1 - 1.3e-32 111.4 0.3 3.1e-32 110.2 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KEY67346.1 - 2.4e-12 46.8 0.0 5.8e-12 45.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEY67346.1 - 0.00029 20.1 0.0 0.00054 19.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 KEY67346.1 - 0.0023 17.7 0.1 0.0056 16.4 0.0 1.7 1 0 0 1 1 1 1 TGS domain PPAK PF02818.10 KEY67346.1 - 0.012 15.4 2.2 0.038 13.9 1.5 1.9 1 0 0 1 1 1 0 PPAK motif MobB PF03205.9 KEY67346.1 - 0.03 14.0 0.3 4 7.1 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 KEY67346.1 - 0.049 13.4 0.1 1.7 8.4 0.0 2.7 1 1 1 3 3 3 0 Dynamin family AAA_14 PF13173.1 KEY67346.1 - 0.058 13.3 0.0 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain BetaGal_dom3 PF13363.1 KEY67346.1 - 0.058 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 AKAP95 PF04988.7 KEY67346.1 - 0.13 11.9 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) AAA_23 PF13476.1 KEY67346.1 - 3.2 8.0 9.5 42 4.3 6.6 2.5 1 1 0 1 1 1 0 AAA domain Ank_5 PF13857.1 KEY67348.1 - 3.8e-19 68.2 0.4 1.6e-11 44.0 0.0 5.0 4 1 1 5 5 5 2 Ankyrin repeats (many copies) VPS9 PF02204.13 KEY67348.1 - 1.1e-18 67.0 0.0 2.7e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 KEY67348.1 - 1.8e-13 50.5 0.0 1.1e-08 35.2 0.0 3.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEY67348.1 - 3.4e-13 49.6 0.0 0.00069 20.0 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY67348.1 - 9.5e-12 43.9 0.1 0.0039 17.2 0.0 5.9 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.25 KEY67348.1 - 3.6e-09 35.9 2.0 0.044 13.6 0.0 5.2 5 1 0 5 5 5 2 Ankyrin repeat PX PF00787.19 KEY67348.1 - 0.0062 16.3 3.0 0.0064 16.2 0.0 2.4 2 1 0 2 2 2 1 PX domain p450 PF00067.17 KEY67349.1 - 1e-67 228.6 0.0 1.2e-67 228.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pro_CA PF00484.14 KEY67350.1 - 5.1e-12 46.0 0.0 6.7e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Pyr_redox_2 PF07992.9 KEY67352.1 - 1.7e-12 47.6 0.0 1.1e-11 44.9 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY67352.1 - 2.8e-11 43.6 0.0 5.7e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY67352.1 - 7.8e-10 39.1 0.3 8.1e-05 22.7 0.1 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEY67352.1 - 9.1e-06 24.8 0.3 0.05 12.5 0.1 2.8 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KEY67352.1 - 0.00032 19.7 1.3 2.5 6.9 0.2 3.7 4 0 0 4 4 4 3 FAD dependent oxidoreductase Med5 PF08689.5 KEY67353.1 - 3.8e-223 743.2 0.0 5.1e-223 742.8 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 alpha-hel2 PF14456.1 KEY67353.1 - 0.072 11.8 0.0 0.15 10.7 0.0 1.5 1 0 0 1 1 1 0 Alpha-helical domain 2 TRAP_alpha PF03896.11 KEY67354.1 - 2.5e-05 23.4 0.1 3.4e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit SNF2_N PF00176.18 KEY67355.1 - 1.1e-56 191.8 1.0 1.9e-56 191.0 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 KEY67355.1 - 4.1e-09 36.1 11.8 9.1e-09 35.0 8.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KEY67355.1 - 2.3e-07 30.3 9.8 4.3e-07 29.5 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEY67355.1 - 7.3e-07 29.1 12.1 1.5e-06 28.0 8.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEY67355.1 - 2.5e-06 27.0 11.4 5.3e-06 25.9 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEY67355.1 - 4.5e-05 23.4 6.4 4.5e-05 23.4 4.5 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KEY67355.1 - 4.8e-05 22.9 11.2 8.6e-05 22.1 7.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KEY67355.1 - 0.0087 15.7 5.5 0.042 13.5 3.6 2.4 1 1 1 2 2 2 1 RING-type zinc-finger Baculo_IE-1 PF05290.6 KEY67355.1 - 0.02 14.6 1.2 0.033 13.9 0.3 1.8 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Helicase_C PF00271.26 KEY67355.1 - 0.032 14.0 0.0 0.092 12.6 0.0 1.9 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 KEY67355.1 - 0.078 12.8 10.6 0.15 11.9 7.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 KEY67355.1 - 0.12 11.9 5.9 0.28 10.7 4.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 KEY67355.1 - 0.38 10.6 6.4 0.93 9.3 4.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KEY67355.1 - 0.45 10.1 7.4 0.96 9.0 5.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 KEY67355.1 - 2.2 7.7 8.1 13 5.3 5.6 2.2 1 1 0 1 1 1 0 P-11 zinc finger IGR PF09597.5 KEY67356.1 - 3.6e-23 81.2 0.0 5.3e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 IGR protein motif Milton PF12448.3 KEY67357.1 - 3e-05 24.2 3.3 4.4e-05 23.7 2.3 1.3 1 0 0 1 1 1 1 Kinesin associated protein bZIP_2 PF07716.10 KEY67357.1 - 0.0011 18.7 11.3 0.0018 18.0 7.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KEY67357.1 - 0.018 14.9 11.3 0.032 14.1 7.8 1.4 1 1 0 1 1 1 0 bZIP transcription factor CAF-1_p150 PF11600.3 KEY67357.1 - 0.11 11.8 13.7 0.14 11.5 9.5 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal bZIP_Maf PF03131.12 KEY67357.1 - 0.45 10.8 8.0 0.81 10.0 5.5 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF936 PF06075.7 KEY67357.1 - 0.52 9.1 6.9 0.6 8.9 4.8 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) NARP1 PF12569.3 KEY67357.1 - 2.4 6.7 5.7 3 6.4 4.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SMAP PF15477.1 KEY67358.1 - 1e-13 51.3 8.6 1e-13 51.3 6.0 6.4 5 3 0 5 5 5 1 Small acidic protein family Utp14 PF04615.8 KEY67358.1 - 3.9 5.5 93.7 5.5 5.0 64.9 1.1 1 0 0 1 1 1 0 Utp14 protein RAMP4 PF06624.7 KEY67359.1 - 7.9e-05 22.1 1.2 0.0001 21.7 0.8 1.3 1 1 0 1 1 1 1 Ribosome associated membrane protein RAMP4 PAT1 PF09770.4 KEY67359.1 - 0.084 11.1 0.1 0.086 11.0 0.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cation_ATPase_N PF00690.21 KEY67360.1 - 0.063 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Ufm1 PF03671.9 KEY67360.1 - 0.12 12.1 0.1 0.26 11.0 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin fold modifier 1 protein Mid1 PF12929.2 KEY67361.1 - 3e-125 418.2 1.4 3.6e-125 418.0 1.0 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component TB2_DP1_HVA22 PF03134.14 KEY67362.1 - 2.7e-30 103.9 6.2 3.7e-30 103.5 4.3 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family 2-Hacid_dh_C PF02826.14 KEY67363.1 - 3.8e-51 172.7 0.0 5.9e-51 172.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KEY67363.1 - 2.1e-35 121.1 0.0 2.8e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KEY67363.1 - 7.5e-05 22.6 0.3 0.00023 21.0 0.1 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KEY67363.1 - 0.0024 17.2 0.1 0.029 13.7 0.0 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain ACT PF01842.20 KEY67363.1 - 0.0098 15.3 0.1 0.03 13.7 0.0 1.9 1 1 0 1 1 1 1 ACT domain AdoHcyase_NAD PF00670.16 KEY67363.1 - 0.02 14.7 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain RFX_DNA_binding PF02257.10 KEY67364.1 - 1.8e-25 88.9 0.1 4.6e-25 87.5 0.0 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain AA_kinase PF00696.23 KEY67365.1 - 2.7e-35 122.0 0.1 4.4e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 KEY67365.1 - 2.3e-09 36.5 0.4 0.0025 17.2 0.0 2.6 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 KEY67365.1 - 5.9e-06 25.7 2.4 0.018 14.5 0.1 2.8 3 0 0 3 3 3 2 ACT domain Sec10 PF07393.6 KEY67366.1 - 1e-156 523.1 0.0 1.4e-156 522.7 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 KEY67366.1 - 1.2e-06 28.1 0.0 3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEY67366.1 - 6.4e-06 25.6 0.1 1.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain Pkinase PF00069.20 KEY67367.1 - 1.1e-63 214.7 0.0 1.3e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY67367.1 - 2.5e-33 115.2 0.0 3.2e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY67367.1 - 0.0051 15.8 0.0 0.0094 14.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEY67367.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Frag1 PF10277.4 KEY67369.1 - 1.2e-39 136.0 8.5 1.3e-39 135.8 5.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DPM2 PF07297.7 KEY67369.1 - 0.079 13.2 0.3 0.32 11.3 0.0 2.0 2 0 0 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) MFS_Mycoplasma PF07672.8 KEY67369.1 - 0.86 8.7 11.2 4.2 6.4 7.7 2.0 1 1 0 1 1 1 0 Mycoplasma MFS transporter DUF4064 PF13273.1 KEY67369.1 - 1.8 8.7 9.2 11 6.2 6.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF3671 PF12420.3 KEY67369.1 - 5.4 7.0 11.8 0.62 10.0 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF3812 PF12757.2 KEY67370.1 - 5.5e-40 136.2 15.3 5.5e-40 136.2 10.6 4.4 2 2 2 4 4 4 1 Protein of unknown function (DUF3812) Y_phosphatase3 PF13350.1 KEY67371.1 - 8.9e-31 107.3 0.5 3e-29 102.3 0.3 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KEY67371.1 - 5.9e-08 32.7 0.0 1.2e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 KEY67371.1 - 0.0022 17.3 0.0 0.0059 15.9 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KEY67371.1 - 0.0071 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.9 KEY67371.1 - 0.01 14.6 0.1 0.02 13.7 0.0 1.4 2 0 0 2 2 2 0 Myotubularin-like phosphatase domain DSPc PF00782.15 KEY67371.1 - 0.019 14.5 0.1 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Methyltransf_12 PF08242.7 KEY67372.1 - 3.6e-13 49.8 0.0 8.5e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY67372.1 - 3.5e-11 43.4 0.0 6.8e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY67372.1 - 8e-11 41.9 0.0 1.3e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY67372.1 - 2.2e-09 37.8 0.0 3.8e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY67372.1 - 7.2e-09 35.9 0.0 1.4e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY67372.1 - 2.5e-08 33.6 0.0 4.2e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY67372.1 - 0.00011 21.4 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.1 KEY67372.1 - 0.00013 22.7 0.0 0.00033 21.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KEY67372.1 - 0.00048 19.1 0.0 0.66 8.9 0.0 2.2 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family MTS PF05175.9 KEY67372.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.10 KEY67372.1 - 0.0024 17.5 0.0 0.007 16.0 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase DUF3419 PF11899.3 KEY67372.1 - 0.0031 16.3 0.0 0.0079 14.9 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3419) Methyltransf_26 PF13659.1 KEY67372.1 - 0.0033 17.4 0.0 0.0068 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 KEY67372.1 - 0.029 13.3 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Ras PF00071.17 KEY67372.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Ras family TPR_14 PF13428.1 KEY67373.1 - 3.1e-10 39.7 2.5 0.00039 20.8 0.0 5.1 5 1 1 6 6 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEY67373.1 - 8.3e-10 38.1 5.5 1.7e-05 24.3 0.1 4.7 3 2 1 5 5 5 1 TPR repeat TPR_16 PF13432.1 KEY67373.1 - 1.6e-09 38.1 0.2 5.7e-05 23.6 0.0 4.1 3 1 3 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEY67373.1 - 1.3e-07 31.8 1.6 0.00012 22.3 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEY67373.1 - 2.5e-07 30.1 5.3 0.00082 19.1 0.1 5.2 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEY67373.1 - 2.7e-05 23.9 0.2 0.0042 17.1 0.0 3.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEY67373.1 - 0.00025 20.5 0.0 0.012 15.1 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KEY67373.1 - 0.00037 20.2 0.2 0.0047 16.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEY67373.1 - 0.00047 19.7 0.0 0.017 14.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 KEY67373.1 - 0.00057 19.9 0.8 0.0075 16.3 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEY67373.1 - 0.00069 19.4 8.0 0.069 13.0 0.1 4.1 3 1 0 4 4 3 2 Tetratricopeptide repeat PCI_Csn8 PF10075.4 KEY67373.1 - 0.0027 17.4 0.1 0.005 16.6 0.1 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 KEY67373.1 - 0.0032 17.1 0.3 0.19 11.6 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEY67373.1 - 0.0038 17.6 2.2 4.4 7.9 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat DUF627 PF04781.7 KEY67373.1 - 0.0092 15.5 0.0 0.044 13.4 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF627) TipAS PF07739.8 KEY67373.1 - 0.045 14.0 0.1 0.55 10.5 0.0 2.7 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain Apc3 PF12895.2 KEY67373.1 - 0.067 13.3 0.0 0.35 11.0 0.0 2.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR_3 PF13812.1 KEY67373.1 - 0.11 12.8 0.0 0.52 10.7 0.0 2.2 1 0 0 1 1 1 0 Pentatricopeptide repeat domain Polyketide_cyc PF03364.15 KEY67376.1 - 9.2e-24 83.8 0.0 1.3e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Adaptin_N PF01602.15 KEY67377.1 - 2.3e-77 260.5 0.0 4.4e-77 259.5 0.0 1.4 1 1 0 1 1 1 1 Adaptin N terminal region RhoGAP PF00620.22 KEY67378.1 - 8.6e-15 54.6 0.1 3.4e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 KEY67378.1 - 8e-14 51.5 0.0 3.2e-13 49.6 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 KEY67378.1 - 5.7e-12 45.2 0.0 1.3e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) KIP1 PF07765.7 KEY67378.1 - 0.045 13.5 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 0 KIP1-like protein Peptidase_M19 PF01244.16 KEY67379.1 - 7.2e-102 340.5 0.0 8.5e-102 340.3 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Ribosomal_S13 PF00416.17 KEY67380.1 - 6.6e-20 71.5 0.0 7.8e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Pro_isomerase PF00160.16 KEY67381.1 - 4.6e-46 156.8 0.4 5.8e-46 156.5 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3696 PF12476.3 KEY67381.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) Trm112p PF03966.11 KEY67382.1 - 2e-16 60.0 0.1 2.5e-16 59.7 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein DUF1451 PF07295.6 KEY67382.1 - 0.092 12.5 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) ATP-synt_S1 PF05827.7 KEY67383.1 - 1.3e-31 110.0 0.0 4e-31 108.3 0.0 1.7 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) PetL PF05115.9 KEY67383.1 - 0.099 12.5 2.0 1.1 9.1 0.5 2.4 1 1 1 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) Nop25 PF09805.4 KEY67384.1 - 2.5e-34 118.3 13.2 2.5e-34 118.3 9.2 2.3 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) RbsD_FucU PF05025.8 KEY67384.1 - 2.1 8.6 7.0 0.23 11.7 0.4 2.2 2 0 0 2 2 2 0 RbsD / FucU transport protein family Tropomyosin_1 PF12718.2 KEY67385.1 - 4.2e-50 169.3 36.6 5.3e-50 168.9 25.4 1.2 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 KEY67385.1 - 3.5e-08 32.8 32.2 6.2e-05 22.1 13.3 2.9 1 1 1 2 2 2 2 Tropomyosin CENP-F_leu_zip PF10473.4 KEY67385.1 - 0.00012 21.9 6.6 0.00012 21.9 4.6 2.9 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 KEY67385.1 - 0.00084 18.5 31.1 0.012 14.7 13.2 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Mod_r PF07200.8 KEY67385.1 - 0.001 18.9 25.4 0.03 14.2 10.5 2.1 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein Myosin_tail_1 PF01576.14 KEY67385.1 - 0.0013 16.5 31.8 0.0016 16.3 22.0 1.1 1 0 0 1 1 1 1 Myosin tail ATG16 PF08614.6 KEY67385.1 - 0.0021 17.8 29.0 0.32 10.7 10.6 2.4 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) FlaC_arch PF05377.6 KEY67385.1 - 0.0025 17.6 18.0 0.17 11.7 0.2 4.4 3 2 1 4 4 4 2 Flagella accessory protein C (FlaC) HALZ PF02183.13 KEY67385.1 - 0.0026 17.4 0.2 0.0026 17.4 0.1 5.0 4 2 2 6 6 5 1 Homeobox associated leucine zipper ADIP PF11559.3 KEY67385.1 - 0.0035 17.2 7.8 0.0035 17.2 5.4 3.0 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.4 KEY67385.1 - 0.0063 16.6 21.9 0.06 13.4 3.0 3.5 1 1 2 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.7 KEY67385.1 - 0.0064 16.2 5.4 0.0064 16.2 3.7 2.2 1 1 1 2 2 2 1 Laminin Domain II APG6 PF04111.7 KEY67385.1 - 0.0069 15.4 34.8 0.046 12.7 12.6 2.0 1 1 1 2 2 2 2 Autophagy protein Apg6 Fib_alpha PF08702.5 KEY67385.1 - 0.0087 16.1 17.6 0.15 12.1 4.5 2.1 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family IncA PF04156.9 KEY67385.1 - 0.0092 15.5 32.0 0.024 14.2 6.2 2.2 1 1 1 2 2 2 1 IncA protein Cast PF10174.4 KEY67385.1 - 0.01 13.9 27.2 0.011 13.8 18.9 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone ERM PF00769.14 KEY67385.1 - 0.016 14.7 36.7 0.036 13.5 12.6 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF4200 PF13863.1 KEY67385.1 - 0.019 14.9 33.4 0.054 13.4 12.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) EzrA PF06160.7 KEY67385.1 - 0.02 13.0 24.2 0.02 13.1 3.7 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Syntaxin-6_N PF09177.6 KEY67385.1 - 0.033 14.5 17.4 3.7 8.0 4.9 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Surfac_D-trimer PF09006.6 KEY67385.1 - 0.048 13.3 8.1 0.053 13.2 0.0 4.1 4 1 1 5 5 4 0 Lung surfactant protein D coiled-coil trimerisation TBPIP PF07106.8 KEY67385.1 - 0.066 12.7 27.4 0.44 10.0 2.8 3.0 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 KEY67385.1 - 0.07 11.7 27.9 0.03 12.9 10.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein NABP PF07990.7 KEY67385.1 - 0.11 11.7 3.4 0.11 11.7 2.3 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP KLRAQ PF10205.4 KEY67385.1 - 0.12 12.4 20.4 0.039 13.9 5.3 2.9 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein TMF_TATA_bd PF12325.3 KEY67385.1 - 0.13 12.0 30.2 0.79 9.4 12.8 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CCDC155 PF14662.1 KEY67385.1 - 0.16 11.5 34.3 0.031 13.8 14.6 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 PilJ PF13675.1 KEY67385.1 - 0.18 12.1 12.8 1.6 9.0 4.7 2.7 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF972 PF06156.8 KEY67385.1 - 0.18 12.1 26.1 3 8.2 1.2 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.17 KEY67385.1 - 0.25 11.3 26.5 3.9 7.5 2.6 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Cortex-I_coil PF09304.5 KEY67385.1 - 0.33 11.0 28.2 1.5 8.8 2.5 3.2 1 1 2 3 3 3 0 Cortexillin I, coiled coil Nup54 PF13874.1 KEY67385.1 - 0.35 10.5 23.1 1.4 8.6 4.2 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Filament PF00038.16 KEY67385.1 - 0.38 10.1 27.4 0.72 9.2 19.0 1.4 1 1 0 1 1 1 0 Intermediate filament protein DUF904 PF06005.7 KEY67385.1 - 0.4 11.0 39.8 1.8 8.9 3.5 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF904) Striatin PF08232.7 KEY67385.1 - 0.43 10.8 25.4 0.71 10.1 10.1 2.2 1 1 0 2 2 2 0 Striatin family DUF869 PF05911.6 KEY67385.1 - 0.46 8.6 25.8 0.57 8.3 8.8 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) NPV_P10 PF05531.7 KEY67385.1 - 0.51 10.6 7.8 3.5 7.9 0.1 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein bZIP_1 PF00170.16 KEY67385.1 - 0.52 10.3 32.3 2.5 8.1 0.9 5.5 1 1 2 4 4 4 0 bZIP transcription factor Fmp27_WPPW PF10359.4 KEY67385.1 - 0.57 8.5 23.0 0.098 11.0 6.4 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF3450 PF11932.3 KEY67385.1 - 0.58 9.3 25.9 3.2 6.9 2.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Prefoldin PF02996.12 KEY67385.1 - 0.6 9.7 31.0 0.28 10.8 3.1 4.0 1 1 2 4 4 4 0 Prefoldin subunit DUF4140 PF13600.1 KEY67385.1 - 0.78 10.2 22.2 1.4 9.4 2.9 3.1 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) WXG100 PF06013.7 KEY67385.1 - 0.99 9.4 17.3 1.8 8.6 1.3 4.1 1 1 2 3 3 3 0 Proteins of 100 residues with WXG Lebercilin PF15619.1 KEY67385.1 - 1.1 8.7 33.5 1.5 8.2 13.1 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TPR_MLP1_2 PF07926.7 KEY67385.1 - 1.1 9.0 34.7 1.5 8.5 7.0 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HalX PF08663.5 KEY67385.1 - 1.1 9.2 18.9 2.5 8.1 1.8 4.2 1 1 1 4 4 4 0 HalX domain IFT46_B_C PF12317.3 KEY67385.1 - 1.2 8.4 7.6 0.24 10.7 2.3 1.7 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal AAA_13 PF13166.1 KEY67385.1 - 1.4 7.2 24.8 9 4.6 17.2 2.0 1 1 0 1 1 1 0 AAA domain DUF1664 PF07889.7 KEY67385.1 - 1.6 8.5 12.8 3.4 7.4 2.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.6 KEY67385.1 - 1.7 7.9 19.2 0.61 9.4 6.5 2.4 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF3287 PF11690.3 KEY67385.1 - 1.7 8.7 11.3 3.3 7.8 4.0 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) DUF812 PF05667.6 KEY67385.1 - 1.8 6.9 25.3 4.5 5.6 17.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Atg14 PF10186.4 KEY67385.1 - 1.9 7.3 24.6 0.2 10.5 12.5 1.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 HOOK PF05622.7 KEY67385.1 - 2.2 6.0 26.6 2.7 5.6 4.4 2.2 1 1 1 2 2 2 0 HOOK protein DUF342 PF03961.8 KEY67385.1 - 2.6 6.3 26.4 0.13 10.6 6.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Taxilin PF09728.4 KEY67385.1 - 3.3 6.6 32.4 2.9 6.8 6.2 2.4 1 1 1 2 2 2 0 Myosin-like coiled-coil protein DUF4482 PF14818.1 KEY67385.1 - 3.4 8.3 27.7 0.27 11.9 3.5 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4482) TMF_DNA_bd PF12329.3 KEY67385.1 - 3.8 7.3 36.7 44 3.9 4.7 3.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Uso1_p115_C PF04871.8 KEY67385.1 - 4.4 7.2 26.9 5.8 6.8 5.2 2.5 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region WEMBL PF05701.6 KEY67385.1 - 4.6 5.5 33.5 1.3e+02 0.8 23.1 2.1 1 1 0 1 1 1 0 Weak chloroplast movement under blue light rRNA_proc-arch PF13234.1 KEY67385.1 - 4.7 6.2 15.9 1.6e+02 1.3 10.9 2.4 1 1 0 1 1 1 0 rRNA-processing arch domain DUF3584 PF12128.3 KEY67385.1 - 4.8 4.3 28.8 11 3.2 19.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) MAD PF05557.8 KEY67385.1 - 4.9 5.1 28.3 18 3.2 19.6 1.7 1 1 0 1 1 1 0 Mitotic checkpoint protein Cep57_CLD_2 PF14197.1 KEY67385.1 - 5.1 7.1 30.2 4.5 7.2 4.3 4.0 2 2 1 3 3 3 0 Centrosome localisation domain of PPC89 Prefoldin_2 PF01920.15 KEY67385.1 - 5.3 6.8 35.5 0.42 10.3 2.7 4.2 2 1 1 3 3 3 0 Prefoldin subunit HSP70 PF00012.15 KEY67385.1 - 5.7 4.7 18.0 7.5 4.3 12.5 1.3 1 0 0 1 1 1 0 Hsp70 protein DUF2937 PF11157.3 KEY67385.1 - 6.8 5.9 10.6 12 5.1 3.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) FUSC PF04632.7 KEY67385.1 - 7.2 4.9 5.7 7.4 4.8 3.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CDC37_N PF03234.9 KEY67385.1 - 7.3 6.8 22.7 67 3.7 15.7 2.2 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF724 PF05266.9 KEY67385.1 - 7.6 6.0 26.5 2.7 7.5 7.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Jnk-SapK_ap_N PF09744.4 KEY67385.1 - 7.8 6.4 26.5 2.2 8.2 11.4 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 HAP1_N PF04849.8 KEY67385.1 - 8.3 5.2 29.5 1.6e+02 1.0 20.5 3.0 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Syntaxin PF00804.20 KEY67385.1 - 9.1 6.5 20.7 29 4.8 2.4 3.0 1 1 1 2 2 1 0 Syntaxin Mnd1 PF03962.10 KEY67385.1 - 9.4 5.8 31.3 15 5.1 10.4 2.3 1 1 1 2 2 2 0 Mnd1 family bZIP_2 PF07716.10 KEY67385.1 - 9.4 6.1 39.8 0.94 9.3 1.5 5.6 2 2 4 6 6 6 0 Basic region leucine zipper DUF3811 PF11656.3 KEY67386.1 - 0.41 10.7 0.1 0.41 10.7 0.1 2.4 3 0 0 3 3 3 0 YjbD family (DUF3811) N-SET PF11764.3 KEY67387.1 - 3.9e-40 137.4 0.1 3.9e-40 137.4 0.1 3.5 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 KEY67387.1 - 2.6e-23 81.0 0.3 5.7e-23 80.0 0.2 1.6 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 KEY67387.1 - 2.2e-22 80.1 0.1 2.2e-22 80.1 0.1 4.6 5 1 0 5 5 5 2 SET domain K_channel_TID PF07941.6 KEY67387.1 - 0.29 11.3 8.2 0.34 11.1 0.9 2.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Zn_clus PF00172.13 KEY67390.1 - 1.3e-08 34.5 7.8 1.9e-08 34.0 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3669 PF12417.3 KEY67391.1 - 7.1e-08 32.0 0.0 1.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Zinc finger protein LRR_8 PF13855.1 KEY67392.1 - 0.64 9.8 5.5 10 5.9 0.1 4.1 5 1 1 6 6 6 0 Leucine rich repeat GAT PF03127.9 KEY67394.1 - 5.1e-16 58.4 0.6 5.1e-16 58.4 0.4 2.0 2 0 0 2 2 2 1 GAT domain VHS PF00790.14 KEY67394.1 - 0.00019 21.1 0.1 0.00058 19.4 0.0 1.8 2 0 0 2 2 2 1 VHS domain RAP-1 PF03085.10 KEY67394.1 - 0.14 11.4 0.1 0.25 10.6 0.1 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) JmjC PF02373.17 KEY67395.1 - 0.086 13.0 0.3 0.36 11.0 0.1 1.9 1 1 1 2 2 2 0 JmjC domain, hydroxylase Glyco_hydro_3 PF00933.16 KEY67396.1 - 4.9e-10 38.8 0.0 6.4e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY67396.1 - 1.4e-09 37.8 0.5 5.4e-07 29.3 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain HA2 PF04408.18 KEY67398.1 - 7.4e-27 93.3 0.2 7.4e-27 93.3 0.1 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KEY67398.1 - 4e-26 91.0 0.0 8.6e-26 90.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold S1 PF00575.18 KEY67398.1 - 9e-14 51.3 1.2 2.1e-13 50.1 0.8 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Helicase_C PF00271.26 KEY67398.1 - 9.9e-13 47.7 0.0 2.3e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEY67398.1 - 2.4e-05 23.9 0.7 6.8e-05 22.4 0.5 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEY67398.1 - 2.7e-05 24.3 0.1 8.1e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KEY67398.1 - 2.9e-05 23.1 0.0 6.3e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 KEY67398.1 - 0.0007 19.2 0.2 0.0023 17.6 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activ_2 PF14532.1 KEY67398.1 - 0.022 14.8 0.0 0.062 13.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.1 KEY67398.1 - 0.076 12.9 0.1 0.41 10.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 KEY67398.1 - 0.082 12.7 0.2 3.1 7.5 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Amidase PF01425.16 KEY67399.1 - 4.7e-82 276.2 0.4 5.9e-82 275.8 0.3 1.1 1 0 0 1 1 1 1 Amidase RNA_GG_bind PF10258.4 KEY67399.1 - 0.034 13.8 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 PHAX RNA-binding domain Dioxygenase_N PF04444.9 KEY67399.1 - 0.14 12.1 0.0 29 4.7 0.0 2.5 2 0 0 2 2 2 0 Catechol dioxygenase N terminus Ribonuclease PF00545.15 KEY67400.1 - 1.6e-19 69.7 0.3 3.6e-19 68.6 0.1 1.5 1 1 1 2 2 2 1 ribonuclease DIM PF08194.7 KEY67400.1 - 0.31 11.0 6.0 0.53 10.2 0.1 2.5 2 0 0 2 2 2 0 DIM protein UBA_4 PF14555.1 KEY67401.1 - 6.3e-11 41.6 0.5 1.3e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.15 KEY67401.1 - 2.6e-09 37.0 0.0 5.9e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 UBX domain SUFU_C PF12470.3 KEY67401.1 - 0.00027 20.6 0.1 0.00055 19.5 0.1 1.5 1 0 0 1 1 1 1 Suppressor of Fused Gli/Ci N terminal binding domain Pkinase PF00069.20 KEY67402.1 - 0.0002 20.5 0.0 0.00034 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LSM PF01423.17 KEY67403.1 - 1.3e-17 63.1 0.0 1.7e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain DUF1751 PF08551.5 KEY67405.1 - 4.1e-06 27.0 0.2 7.6e-06 26.1 0.2 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 KEY67405.1 - 0.00013 21.9 2.9 0.00028 20.9 2.0 1.5 1 1 0 1 1 1 1 Rhomboid family DER1 PF04511.10 KEY67405.1 - 0.0007 19.1 2.2 0.00095 18.7 1.5 1.2 1 0 0 1 1 1 1 Der1-like family Uds1 PF15456.1 KEY67406.1 - 1.1e-44 151.3 5.2 1.1e-44 151.3 3.6 8.8 4 1 4 8 8 8 1 Up-regulated During Septation Tropomyosin PF00261.15 KEY67406.1 - 0.00027 20.1 44.3 0.00027 20.1 30.7 7.6 5 1 2 7 7 7 3 Tropomyosin MOSC PF03473.12 KEY67406.1 - 0.026 14.0 0.0 0.087 12.2 0.0 1.9 1 0 0 1 1 1 0 MOSC domain Myosin_tail_1 PF01576.14 KEY67406.1 - 0.14 9.8 135.9 0.0085 13.8 24.7 5.4 3 2 2 4 4 4 0 Myosin tail Reo_sigmaC PF04582.7 KEY67406.1 - 1.4 7.9 43.6 0.37 9.9 9.4 5.3 2 1 5 7 7 7 0 Reovirus sigma C capsid protein Tcp11 PF05794.8 KEY67407.1 - 4.9e-86 289.1 1.4 2.8e-79 266.9 2.1 2.1 2 0 0 2 2 2 2 T-complex protein 11 TFIID-18kDa PF02269.11 KEY67408.1 - 3.6e-19 68.3 0.4 5.3e-19 67.8 0.0 1.4 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 KEY67408.1 - 0.001 18.7 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 KEY67408.1 - 0.0027 17.7 0.0 0.006 16.6 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KEY67408.1 - 0.072 13.1 0.5 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 KEY67408.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Kinetochore component CENP-S EamA PF00892.15 KEY67409.1 - 1.3e-17 63.9 25.7 1.5e-10 41.1 4.8 2.5 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KEY67409.1 - 0.00014 22.0 4.9 0.00014 22.0 3.4 3.1 2 2 0 2 2 2 1 Multidrug resistance efflux transporter TIP49 PF06068.8 KEY67410.1 - 7.1e-179 594.6 0.3 9.1e-179 594.2 0.2 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KEY67410.1 - 1.9e-11 44.2 0.1 1e-07 32.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KEY67410.1 - 1.7e-09 37.0 2.5 6e-07 28.7 0.0 3.1 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KEY67410.1 - 2.9e-05 23.7 0.2 9.8e-05 22.0 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KEY67410.1 - 7.9e-05 22.8 0.3 0.46 10.6 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 KEY67410.1 - 0.00032 20.7 0.0 0.082 12.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 KEY67410.1 - 0.00077 19.4 0.1 0.0017 18.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEY67410.1 - 0.0013 18.1 0.1 0.0084 15.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KEY67410.1 - 0.0046 16.0 0.3 0.014 14.4 0.2 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.9 KEY67410.1 - 0.0054 16.4 0.1 0.11 12.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KEY67410.1 - 0.0098 15.3 0.1 0.022 14.1 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF2075 PF09848.4 KEY67410.1 - 0.013 14.4 0.1 0.044 12.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 KEY67410.1 - 0.021 15.1 0.1 0.048 13.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KEY67410.1 - 0.022 14.2 0.1 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 KEY67410.1 - 0.024 13.8 0.1 0.59 9.2 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DnaB_C PF03796.10 KEY67410.1 - 0.051 12.4 0.0 0.098 11.5 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain MinE PF03776.9 KEY67410.1 - 0.084 12.3 0.1 0.21 11.1 0.1 1.6 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE AAA_17 PF13207.1 KEY67410.1 - 0.1 13.4 0.1 0.25 12.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain Dynactin PF12455.3 KEY67411.1 - 2.9e-90 301.9 5.4 2.9e-90 301.9 3.8 3.0 4 0 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 KEY67411.1 - 1.1e-23 82.7 0.9 1.9e-23 81.9 0.6 1.4 1 0 0 1 1 1 1 CAP-Gly domain HMG_box PF00505.14 KEY67411.1 - 4e-21 75.0 1.4 4e-21 75.0 1.0 2.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KEY67411.1 - 6.6e-06 26.3 0.8 4.5e-05 23.7 0.6 2.6 1 0 0 1 1 1 1 HMG-box domain SRP19 PF01922.12 KEY67412.1 - 1e-26 93.3 0.0 1.9e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein Endonuc-BglII PF09195.6 KEY67413.1 - 0.12 11.8 0.2 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 Restriction endonuclease BglII DUF342 PF03961.8 KEY67413.1 - 0.17 10.2 1.6 0.25 9.7 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF605 PF04652.11 KEY67413.1 - 0.54 9.6 9.1 0.87 8.9 6.3 1.3 1 0 0 1 1 1 0 Vta1 like zf-CCCH PF00642.19 KEY67413.1 - 0.8 9.4 4.0 1.9 8.2 2.8 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Macoilin PF09726.4 KEY67413.1 - 1.3 7.2 6.1 1.7 6.7 4.2 1.1 1 0 0 1 1 1 0 Transmembrane protein IncA PF04156.9 KEY67413.1 - 2.1 7.8 7.8 3.3 7.2 5.4 1.3 1 0 0 1 1 1 0 IncA protein Zn_clus PF00172.13 KEY67414.1 - 2.1e-08 33.9 11.3 3.5e-08 33.2 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY67414.1 - 3.4e-08 32.6 0.2 6.7e-08 31.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain CDP-OH_P_transf PF01066.16 KEY67415.1 - 2e-18 66.5 3.8 2e-18 66.5 2.6 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase OMPdecase PF00215.19 KEY67416.1 - 7.4e-98 326.4 0.0 1.1e-97 325.8 0.0 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family PP2C PF00481.16 KEY67417.1 - 4.3e-37 127.8 0.0 1.8e-31 109.4 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 KEY67417.1 - 2.2e-06 27.2 0.0 4.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Het-C PF07217.6 KEY67418.1 - 9.5e-277 919.1 0.0 1.2e-276 918.7 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C KdpC PF02669.10 KEY67418.1 - 0.04 13.6 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 K+-transporting ATPase, c chain Cyt-b5 PF00173.23 KEY67419.1 - 1.4e-18 66.4 0.6 4.2e-18 64.9 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 KEY67419.1 - 4.8e-09 36.6 22.2 6.3e-09 36.2 13.7 2.0 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 KEY67419.1 - 0.048 13.6 0.1 0.084 12.8 0.1 1.3 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region COX14 PF14880.1 KEY67419.1 - 0.092 12.3 2.9 0.17 11.5 0.3 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c assembly RRM_1 PF00076.17 KEY67420.1 - 2.6e-42 142.3 2.3 8.8e-19 66.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY67420.1 - 1.1e-31 108.6 0.4 2.5e-16 59.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 KEY67420.1 - 4.5e-27 94.1 0.1 9.3e-27 93.1 0.1 1.5 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 KEY67420.1 - 2e-19 69.1 0.1 1.4e-06 28.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KEY67420.1 - 0.0092 15.8 1.1 0.13 12.0 0.0 2.8 3 1 0 3 3 3 1 RNA binding motif Atg14 PF10186.4 KEY67421.1 - 0.011 14.7 1.3 0.018 14.0 0.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3150 PF11348.3 KEY67421.1 - 0.053 12.6 0.1 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3150) Cob_adeno_trans PF01923.13 KEY67421.1 - 0.056 13.2 0.5 0.12 12.0 0.1 1.7 2 0 0 2 2 2 0 Cobalamin adenosyltransferase Mnd1 PF03962.10 KEY67421.1 - 0.1 12.2 1.2 0.19 11.3 0.8 1.5 1 0 0 1 1 1 0 Mnd1 family VWA PF00092.23 KEY67422.1 - 2.2e-08 34.0 0.0 6.8e-08 32.4 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KEY67422.1 - 8.7e-07 29.1 0.0 1.4e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KEY67422.1 - 3.2e-05 23.8 0.0 4.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.1 KEY67422.1 - 0.088 12.4 0.0 0.22 11.2 0.0 1.7 1 1 0 1 1 1 0 von Willebrand factor type A domain Aminotran_1_2 PF00155.16 KEY67423.1 - 6.5e-30 104.2 0.0 9e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KEY67423.1 - 0.16 11.0 0.0 0.34 10.0 0.0 1.5 2 0 0 2 2 2 0 Beta-eliminating lyase bZIP_2 PF07716.10 KEY67425.1 - 6.2e-12 45.1 12.0 9.5e-12 44.5 8.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KEY67425.1 - 0.00046 20.0 15.0 0.0022 17.9 10.4 1.9 1 1 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.13 KEY67425.1 - 0.072 13.0 1.0 0.15 12.0 0.7 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family HAUS6_N PF14661.1 KEY67425.1 - 0.31 10.3 9.4 0.42 9.9 6.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4228 PF14009.1 KEY67425.1 - 0.4 10.7 5.8 0.65 10.1 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) IncA PF04156.9 KEY67425.1 - 0.61 9.6 4.9 0.87 9.1 3.4 1.2 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 KEY67425.1 - 3.8 7.9 8.3 0.74 10.1 2.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 KEY67425.1 - 3.9 5.1 6.7 5 4.8 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HDV_ag PF01517.13 KEY67425.1 - 4.1 7.0 11.3 2.6 7.7 2.0 2.3 1 1 1 2 2 2 0 Hepatitis delta virus delta antigen CENP-N PF05238.8 KEY67426.1 - 1.7e-117 392.8 0.0 1.9e-117 392.6 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like TatD_DNase PF01026.16 KEY67427.1 - 1.4e-47 162.0 0.0 3.6e-47 160.7 0.0 1.6 1 1 0 1 1 1 1 TatD related DNase Ribonuc_red_lgC PF02867.10 KEY67428.1 - 3.2e-223 742.1 0.0 4.3e-223 741.7 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KEY67428.1 - 2.8e-24 84.7 0.0 1.1e-23 82.7 0.0 2.1 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 KEY67428.1 - 5.4e-17 62.0 0.0 2.2e-16 60.0 0.0 2.1 2 0 0 2 2 2 1 ATP cone domain CITED PF04487.7 KEY67428.1 - 0.073 13.2 0.3 1.2 9.3 0.0 2.6 3 0 0 3 3 3 0 CITED CFEM PF05730.6 KEY67429.1 - 9.3e-13 47.7 4.0 1.6e-12 47.0 2.8 1.4 1 0 0 1 1 1 1 CFEM domain FlgD_ig PF13860.1 KEY67429.1 - 0.3 10.8 4.3 0.17 11.6 0.3 2.3 2 0 0 2 2 2 0 FlgD Ig-like domain TrbL PF04610.9 KEY67429.1 - 5.8 6.5 10.1 2.2 7.8 3.4 2.6 1 1 1 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein Pirin PF02678.11 KEY67430.1 - 3.1e-32 110.6 0.0 8.9e-31 105.9 0.0 2.3 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 KEY67430.1 - 5.6e-27 93.8 0.0 1.4e-25 89.3 0.0 2.3 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 KEY67430.1 - 1.1e-09 37.6 1.2 7.4e-06 25.3 0.2 2.6 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KEY67430.1 - 0.00078 18.7 0.2 0.41 10.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Perilipin PF03036.11 KEY67431.1 - 5.3e-05 22.2 0.0 5.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Perilipin family DENN PF02141.16 KEY67432.1 - 1.6e-40 138.7 0.1 2.9e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KEY67432.1 - 2.5e-06 27.3 0.0 1.8e-05 24.5 0.0 2.5 2 0 0 2 2 2 1 uDENN domain Elongin_A PF06881.6 KEY67432.1 - 0.0016 18.8 3.0 0.0016 18.8 2.1 2.8 4 0 0 4 4 4 1 RNA polymerase II transcription factor SIII (Elongin) subunit A PCRF PF03462.13 KEY67432.1 - 1.3 8.7 7.0 0.84 9.3 0.1 3.0 3 0 0 3 3 3 0 PCRF domain zf-HIT PF04438.11 KEY67433.1 - 1.2e-08 34.4 9.9 1.8e-08 33.8 6.8 1.3 1 0 0 1 1 1 1 HIT zinc finger Sec6 PF06046.8 KEY67434.1 - 1.3e-157 525.3 8.9 1.7e-157 524.9 6.1 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.7 KEY67434.1 - 0.0001 21.2 1.1 0.00055 18.8 0.1 2.5 2 0 0 2 2 2 1 Vps53-like, N-terminal FAD_binding_2 PF00890.19 KEY67434.1 - 0.014 14.2 0.0 0.05 12.4 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain MutS_III PF05192.13 KEY67434.1 - 0.091 12.5 0.5 1 9.1 0.3 2.9 1 1 0 1 1 1 0 MutS domain III DASH_Dam1 PF08653.5 KEY67434.1 - 2.7 7.8 5.1 18 5.2 0.1 3.9 3 1 1 4 4 4 0 DASH complex subunit Dam1 EF-hand_4 PF12763.2 KEY67435.1 - 9.1e-36 121.7 0.0 8.2e-14 51.2 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.26 KEY67435.1 - 5.2e-07 29.3 0.0 1.2e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.1 KEY67435.1 - 6.6e-06 26.1 0.0 0.024 14.7 0.0 3.6 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.1 KEY67435.1 - 0.00034 20.2 0.0 0.8 9.7 0.0 4.4 5 0 0 5 5 5 1 EF-hand domain DUF812 PF05667.6 KEY67435.1 - 0.00035 19.2 17.6 0.00061 18.4 12.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) EF-hand_1 PF00036.27 KEY67435.1 - 0.0028 16.8 0.0 4.1 6.9 0.0 4.1 4 0 0 4 4 4 1 EF hand TPR_MLP1_2 PF07926.7 KEY67435.1 - 0.003 17.3 35.1 0.0091 15.7 13.7 2.3 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 KEY67435.1 - 0.0031 15.3 26.7 0.0054 14.5 18.5 1.3 1 0 0 1 1 1 1 Myosin tail Macoilin PF09726.4 KEY67435.1 - 0.0063 14.8 18.7 0.0099 14.2 13.0 1.2 1 0 0 1 1 1 1 Transmembrane protein CENP-F_leu_zip PF10473.4 KEY67435.1 - 0.012 15.4 27.9 0.021 14.6 10.5 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 KEY67435.1 - 0.092 12.1 28.1 0.13 11.7 6.9 2.2 1 1 1 2 2 2 0 Intermediate filament protein Spc7 PF08317.6 KEY67435.1 - 0.19 10.3 28.1 1 7.9 8.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.7 KEY67435.1 - 0.27 11.0 12.4 0.033 13.9 4.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) GAS PF13851.1 KEY67435.1 - 0.51 9.4 29.2 0.75 8.9 9.9 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 KEY67435.1 - 0.58 9.7 35.4 0.16 11.5 13.7 2.2 1 1 1 2 2 2 0 IncA protein ATG16 PF08614.6 KEY67435.1 - 0.72 9.6 35.6 1.5 8.5 12.5 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MAD PF05557.8 KEY67435.1 - 1.2 7.1 28.1 1.8 6.5 19.5 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Mnd1 PF03962.10 KEY67435.1 - 1.3 8.6 29.2 1.9 8.1 6.1 2.3 1 1 1 2 2 2 0 Mnd1 family AAA_13 PF13166.1 KEY67435.1 - 1.3 7.3 21.4 2.2 6.6 14.9 1.3 1 0 0 1 1 1 0 AAA domain DUF4201 PF13870.1 KEY67435.1 - 1.4 8.3 29.2 0.54 9.6 8.5 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) TMF_TATA_bd PF12325.3 KEY67435.1 - 2.7 7.7 25.7 2.8 7.6 1.4 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF2730 PF10805.3 KEY67435.1 - 3.6 7.3 8.6 22 4.8 3.1 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF2730) DUF4239 PF14023.1 KEY67435.1 - 9 5.5 5.1 16 4.7 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) APG6 PF04111.7 KEY67435.1 - 9.8 5.1 32.4 9.3 5.1 13.0 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 Pyr_redox_2 PF07992.9 KEY67436.1 - 1.6e-40 139.1 0.0 3.1e-40 138.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KEY67436.1 - 4.6e-34 116.7 0.4 1.2e-33 115.4 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KEY67436.1 - 5.5e-22 77.9 0.9 1.8e-19 69.9 0.0 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY67436.1 - 4.5e-13 49.7 0.7 2.5e-10 40.7 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEY67436.1 - 6.5e-07 28.5 0.1 0.00072 18.5 0.0 2.2 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KEY67436.1 - 3.5e-05 22.4 1.1 0.13 10.7 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.2 KEY67436.1 - 0.01 14.9 0.2 0.017 14.1 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KEY67436.1 - 0.011 15.3 0.0 0.011 15.3 0.0 2.2 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KEY67436.1 - 0.011 15.2 0.3 0.52 9.8 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 KEY67436.1 - 0.017 14.0 0.1 0.12 11.2 0.1 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KEY67436.1 - 0.12 11.1 2.9 2 7.1 0.6 2.6 3 0 0 3 3 3 0 FAD binding domain 2-Hacid_dh_C PF02826.14 KEY67436.1 - 0.19 10.8 2.7 0.5 9.4 0.1 2.5 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 KEY67436.1 - 0.59 8.9 9.9 0.43 9.4 0.5 2.8 3 1 0 3 3 3 0 FAD dependent oxidoreductase Ecl1 PF12855.2 KEY67437.1 - 1.8e-10 39.9 1.4 3.7e-10 38.9 0.9 1.6 1 0 0 1 1 1 1 Life-span regulatory factor DUF329 PF03884.9 KEY67437.1 - 0.037 13.5 2.8 0.077 12.5 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF329) DUF2116 PF09889.4 KEY67437.1 - 0.05 13.3 0.2 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Metallothio_Pro PF02069.11 KEY67437.1 - 0.078 12.8 2.3 0.2 11.5 1.6 1.8 1 0 0 1 1 1 0 Prokaryotic metallothionein zf-MYND PF01753.13 KEY67437.1 - 0.99 9.3 4.2 2.2 8.2 2.9 1.6 1 0 0 1 1 1 0 MYND finger Cpn60_TCP1 PF00118.19 KEY67440.1 - 2.5e-162 540.8 0.8 2.9e-162 540.6 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.7 KEY67441.1 - 5.2e-38 129.7 10.0 6.9e-38 129.3 6.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF1777 PF08648.7 KEY67441.1 - 0.4 10.3 18.8 0.61 9.7 13.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) His_Phos_1 PF00300.17 KEY67442.1 - 6.7e-31 107.5 0.0 1.4e-30 106.4 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 KEY67442.1 - 0.00022 20.6 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HATPase_c PF02518.21 KEY67443.1 - 1.6e-24 85.7 0.2 3.6e-24 84.6 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KEY67443.1 - 4.4e-21 74.6 0.8 1.1e-20 73.4 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 KEY67443.1 - 2e-20 72.8 0.0 5.1e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.6 KEY67443.1 - 1.5e-18 66.6 1.7 3.3e-09 36.7 0.5 3.9 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.1 KEY67443.1 - 3.7e-14 52.9 0.0 5.2e-08 33.1 0.0 3.4 2 1 0 2 2 2 2 PAS domain PAS_4 PF08448.5 KEY67443.1 - 2.5e-06 27.5 3.0 3.9e-05 23.6 0.1 3.4 3 0 0 3 3 3 1 PAS fold PAS PF00989.19 KEY67443.1 - 2.9e-05 23.8 0.0 0.56 10.0 0.0 3.2 3 0 0 3 3 3 2 PAS fold Cytochrom_B561 PF03188.11 KEY67444.1 - 5.6e-16 58.6 10.7 6.8e-16 58.3 6.8 1.5 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 PepSY_TM_1 PF13172.1 KEY67444.1 - 0.0092 15.7 0.1 0.0092 15.7 0.1 4.0 4 0 0 4 4 4 1 PepSY-associated TM helix Cytochrom_B_N PF00033.14 KEY67444.1 - 0.012 14.9 13.7 0.031 13.6 3.1 2.5 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF202 PF02656.10 KEY67444.1 - 0.18 12.0 8.7 2 8.7 0.4 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF202) DUF2306 PF10067.4 KEY67444.1 - 1.9 8.6 17.9 0.29 11.2 0.2 3.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) DUF4006 PF13179.1 KEY67444.1 - 4.3 6.9 9.8 2.3 7.8 0.2 3.7 4 0 0 4 4 4 0 Family of unknown function (DUF4006) DUF3619 PF12279.3 KEY67444.1 - 5.2 7.1 5.8 1.7 8.7 0.2 2.8 2 1 2 4 4 4 0 Protein of unknown function (DUF3619) Allantoicase PF03561.10 KEY67445.1 - 1.3e-107 355.8 0.4 9.6e-58 193.9 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat DIL PF01843.14 KEY67446.1 - 3.3e-19 68.6 5.4 5.2e-13 48.7 0.3 2.9 3 0 0 3 3 3 2 DIL domain Ank_2 PF12796.2 KEY67446.1 - 3.7e-19 68.8 0.0 8.7e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KEY67446.1 - 4.6e-17 60.8 0.0 1.2e-07 31.1 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 KEY67446.1 - 2.2e-15 56.7 0.0 6e-08 32.9 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY67446.1 - 4.9e-12 45.6 0.1 3.1e-07 30.4 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY67446.1 - 4.8e-11 41.7 0.1 0.0013 18.7 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat RabGAP-TBC PF00566.13 KEY67448.1 - 1.8e-35 122.4 0.0 2.6e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FA_desaturase PF00487.19 KEY67449.1 - 3.8e-23 82.2 17.1 3.8e-23 82.2 11.9 1.4 2 0 0 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.3 KEY67449.1 - 2.6e-07 30.7 0.0 5.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DDE_Tnp_1_7 PF13843.1 KEY67449.1 - 9.8e-07 28.1 0.1 1.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1_7 PF13843.1 KEY67450.1 - 0.00021 20.4 0.0 0.00037 19.6 0.0 1.3 1 0 0 1 1 1 1 Transposase IS4 RGM_N PF06535.7 KEY67450.1 - 0.39 10.7 3.6 0.69 9.9 2.5 1.4 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) N-terminus DDE_Tnp_1_7 PF13843.1 KEY67451.1 - 4.5e-38 131.1 0.0 6.1e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 p450 PF00067.17 KEY67453.1 - 2.4e-41 141.7 0.0 2.7e-37 128.3 0.0 2.0 1 1 0 2 2 2 2 Cytochrome P450 eIF-5_eIF-2B PF01873.12 KEY67454.1 - 2.9e-41 140.0 0.0 5.1e-41 139.2 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 KEY67454.1 - 4.1e-25 87.5 0.8 1.2e-24 86.0 0.6 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon efThoc1 PF11957.3 KEY67455.1 - 3e-149 497.6 0.2 4.1e-149 497.2 0.1 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.16 KEY67455.1 - 1.2e-23 83.5 0.0 6.4e-21 74.6 0.0 2.5 2 0 0 2 2 2 2 Guanylate kinase AAA_12 PF13087.1 KEY67456.1 - 1e-27 96.8 0.0 1.8e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KEY67456.1 - 9.8e-22 77.6 0.0 3.2e-21 76.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEY67456.1 - 1.2e-09 37.8 0.1 1e-08 34.8 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KEY67456.1 - 3.4e-05 23.5 0.0 0.0025 17.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 KEY67456.1 - 0.00015 21.6 0.0 0.00031 20.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KEY67456.1 - 0.0015 18.7 0.0 0.016 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KEY67456.1 - 0.0024 17.3 0.0 0.0063 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KEY67456.1 - 0.0035 17.5 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 KEY67456.1 - 0.0042 16.5 0.0 0.031 13.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_16 PF13191.1 KEY67456.1 - 0.0043 17.0 0.2 0.022 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 KEY67456.1 - 0.012 14.7 0.0 0.037 13.1 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 KEY67456.1 - 0.019 15.7 0.1 0.58 10.9 0.0 3.2 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KEY67456.1 - 0.028 13.4 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 KEY67456.1 - 0.029 13.2 0.0 0.058 12.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 KEY67456.1 - 0.038 14.1 0.0 0.56 10.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 KEY67456.1 - 0.068 12.8 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase Viral_helicase1 PF01443.13 KEY67456.1 - 0.071 12.6 0.2 3.8 6.9 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 KEY67456.1 - 0.15 11.3 1.1 0.48 9.6 0.0 2.3 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain DnaB_C PF03796.10 KEY67456.1 - 0.15 10.9 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PIF1 PF05970.9 KEY67456.1 - 0.16 10.8 0.0 14 4.4 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Parvo_NS1 PF01057.12 KEY67456.1 - 0.27 10.0 0.0 0.46 9.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Lactamase_B_2 PF12706.2 KEY67457.1 - 0.00048 19.7 1.1 0.00093 18.7 0.2 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KEY67457.1 - 0.014 15.0 1.3 0.014 15.0 0.9 1.9 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Mod_r PF07200.8 KEY67458.1 - 8.7e-11 41.9 0.5 1.3e-10 41.4 0.3 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein F-box PF00646.28 KEY67460.1 - 0.00017 21.1 0.3 0.00042 19.9 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KEY67460.1 - 0.00018 21.1 0.2 0.00018 21.1 0.2 2.0 2 0 0 2 2 2 1 F-box-like tRNA-synt_2b PF00587.20 KEY67463.1 - 8.6e-35 119.8 0.0 1.3e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Prefoldin PF02996.12 KEY67463.1 - 1.1e-13 50.9 0.0 2.5e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Prefoldin subunit HGTP_anticodon PF03129.15 KEY67463.1 - 3.8e-10 39.5 0.0 7.8e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain CBF PF03914.12 KEY67464.1 - 8.1e-46 155.4 1.4 2.1e-45 154.1 0.0 2.3 2 0 0 2 2 2 1 CBF/Mak21 family APS_kinase PF01583.15 KEY67465.1 - 4.9e-72 240.7 0.0 6e-72 240.4 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 KEY67465.1 - 1.3e-08 34.8 0.0 1.9e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEY67465.1 - 9.1e-07 29.7 0.0 1.3e-06 29.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEY67465.1 - 2.1e-05 24.8 0.0 4.4e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 KEY67465.1 - 8.1e-05 21.9 0.0 0.00014 21.1 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 KEY67465.1 - 0.0012 18.0 0.0 0.0021 17.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin PRK PF00485.13 KEY67465.1 - 0.0039 16.7 0.0 0.0054 16.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 KEY67465.1 - 0.004 17.1 0.7 0.016 15.1 0.5 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 KEY67465.1 - 0.0095 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_26 PF13500.1 KEY67465.1 - 0.014 15.0 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KEY67465.1 - 0.025 14.8 0.0 0.046 14.0 0.0 1.4 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 KEY67465.1 - 0.037 14.1 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Torsin PF06309.6 KEY67465.1 - 0.13 12.2 0.0 0.4 10.5 0.0 1.7 2 0 0 2 2 2 0 Torsin Thymidylate_kin PF02223.12 KEY67465.1 - 0.13 11.6 0.0 0.35 10.2 0.0 1.8 1 1 1 2 2 2 0 Thymidylate kinase V-ATPase_C PF03223.10 KEY67466.1 - 8.5e-115 383.5 0.2 9.5e-115 383.4 0.2 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.10 KEY67466.1 - 0.0044 17.3 0.8 0.016 15.5 0.1 2.2 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain ScpA_ScpB PF02616.9 KEY67466.1 - 0.026 14.1 0.1 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 ScpA/B protein AAA PF00004.24 KEY67467.1 - 2.8e-15 56.6 0.0 1.4e-14 54.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEY67467.1 - 3.8e-11 43.3 0.0 3.7e-10 40.1 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEY67467.1 - 5.2e-09 36.3 0.0 1.7e-07 31.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain BAH PF01426.13 KEY67467.1 - 5.7e-09 35.7 0.0 1.5e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.1 KEY67467.1 - 5.7e-05 22.7 0.0 0.00024 20.7 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KEY67467.1 - 0.00037 21.3 0.0 0.011 16.4 0.0 3.2 4 0 0 4 4 3 1 AAA domain Arch_ATPase PF01637.13 KEY67467.1 - 0.00088 19.0 0.0 0.0069 16.1 0.0 2.2 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 KEY67467.1 - 0.0013 18.4 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.4 KEY67467.1 - 0.0026 16.8 0.0 0.004 16.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 KEY67467.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 KEY67467.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_18 PF13238.1 KEY67467.1 - 0.018 15.3 0.0 0.047 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KEY67467.1 - 0.02 14.8 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KEY67467.1 - 0.032 13.9 0.2 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_32 PF13654.1 KEY67467.1 - 0.032 12.9 0.0 0.049 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Toxin_58 PF15536.1 KEY67467.1 - 0.036 13.9 0.0 0.09 12.6 0.0 1.7 1 0 0 1 1 1 0 Putative toxin 58 KAP_NTPase PF07693.9 KEY67467.1 - 0.037 13.0 0.0 0.34 9.8 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.17 KEY67467.1 - 0.041 14.0 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase UvrD-helicase PF00580.16 KEY67467.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 KEY67467.1 - 0.2 10.6 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase WD40 PF00400.27 KEY67468.1 - 1.4e-54 180.1 16.2 1.5e-09 37.3 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KEY67468.1 - 0.015 13.4 5.6 8.9 4.3 0.0 4.3 1 1 4 5 5 5 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KEY67468.1 - 0.052 12.3 0.0 7.1 5.2 0.0 2.9 1 1 0 3 3 3 0 Nup133 N terminal like Ank_5 PF13857.1 KEY67469.1 - 9.8e-48 159.1 8.7 7.9e-11 41.8 0.0 5.4 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEY67469.1 - 6.5e-41 138.5 2.0 2.6e-14 53.3 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEY67469.1 - 1e-36 122.8 1.7 6.1e-05 22.6 0.1 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KEY67469.1 - 2.9e-35 119.9 3.8 1.4e-09 38.2 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY67469.1 - 3.4e-32 107.2 0.6 0.0013 18.7 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat TMF_TATA_bd PF12325.3 KEY67470.1 - 1.2e-39 134.7 10.2 1.2e-39 134.7 7.1 7.1 2 1 3 6 6 6 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 KEY67470.1 - 4.8e-16 58.3 10.0 4.8e-16 58.3 6.9 9.7 7 3 3 10 10 10 2 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.2 KEY67470.1 - 0.00074 19.3 17.1 0.00074 19.3 11.8 5.8 4 1 2 6 6 6 2 Tropomyosin like NPV_P10 PF05531.7 KEY67470.1 - 0.36 11.1 21.3 2.7 8.2 0.1 5.5 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Filament PF00038.16 KEY67470.1 - 3 7.2 85.5 12 5.1 5.7 4.6 2 1 1 3 3 3 0 Intermediate filament protein Got1 PF04178.7 KEY67471.1 - 8.5e-31 106.5 17.0 1.1e-30 106.1 11.8 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Peptidase_M50 PF02163.17 KEY67471.1 - 0.026 13.5 0.0 0.036 13.0 0.0 1.4 1 1 0 1 1 1 0 Peptidase family M50 NfeD PF01957.13 KEY67471.1 - 2.4 8.2 5.0 1.6 8.8 2.1 1.6 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding HLH PF00010.21 KEY67472.1 - 3.6e-12 45.7 0.0 1.5e-11 43.8 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3734 PF12536.3 KEY67472.1 - 0.19 11.8 2.5 1.2 9.2 0.1 2.5 3 0 0 3 3 3 0 Patatin phospholipase FG-GAP PF01839.18 KEY67472.1 - 2.7 7.8 6.2 0.61 9.8 0.9 2.6 3 0 0 3 3 3 0 FG-GAP repeat NPR3 PF03666.8 KEY67473.1 - 3.1e-126 421.5 0.2 3.9e-126 421.2 0.2 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Choline_kinase PF01633.15 KEY67474.1 - 1.2e-50 172.0 0.0 9.5e-50 169.0 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 KEY67474.1 - 1.2e-11 44.8 1.2 2.3e-11 43.8 0.8 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KEY67474.1 - 1.3e-07 31.1 0.0 2.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 KEY67474.1 - 0.0013 17.4 0.0 0.0019 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) zf-C2H2_4 PF13894.1 KEY67475.1 - 0.015 15.6 0.1 0.015 15.6 0.0 6.3 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY67475.1 - 2.2 8.8 31.5 0.98 9.9 0.1 6.7 6 0 0 6 6 6 0 Zinc finger, C2H2 type Sugar_tr PF00083.19 KEY67476.1 - 4.4e-20 71.6 25.8 1.4e-13 50.2 5.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter DUF3611 PF12263.3 KEY67476.1 - 0.004 16.5 0.2 0.01 15.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) Pkinase PF00069.20 KEY67477.1 - 1.3e-59 201.4 0.0 6.3e-39 133.6 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEY67477.1 - 4.9e-27 94.6 0.0 3.3e-20 72.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 KEY67477.1 - 9.9e-14 51.3 0.0 2.1e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 KEY67477.1 - 8.6e-08 31.4 0.0 1.5e-05 24.1 0.0 2.6 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KEY67477.1 - 6.3e-06 26.0 0.0 0.0043 16.8 0.1 2.8 1 1 0 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEY67477.1 - 0.032 13.0 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 KEY67477.1 - 0.036 13.1 0.0 0.068 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family bZIP_1 PF00170.16 KEY67478.1 - 0.0014 18.5 11.5 0.0052 16.7 8.0 1.9 1 1 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.5 KEY67478.1 - 0.57 9.8 0.0 0.57 9.8 0.0 3.1 2 1 0 3 3 3 0 Transcription factor PAP1 IncA PF04156.9 KEY67478.1 - 4 6.9 5.8 6.3 6.3 4.0 1.2 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 KEY67478.1 - 7.3 6.9 13.4 0.048 13.9 1.9 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF904) La PF05383.12 KEY67479.1 - 6.3e-19 67.5 0.0 9.9e-19 66.8 0.0 1.3 1 0 0 1 1 1 1 La domain Nitrate_red_gam PF02665.9 KEY67480.1 - 0.013 14.8 6.0 0.037 13.3 1.0 2.3 1 1 1 2 2 2 0 Nitrate reductase gamma subunit VP40 PF07447.7 KEY67480.1 - 0.065 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Matrix protein VP40 Pec_lyase_C PF00544.14 KEY67481.1 - 3.1e-41 141.0 0.9 6e-41 140.1 0.6 1.5 1 1 0 1 1 1 1 Pectate lyase CBM_1 PF00734.13 KEY67481.1 - 5.7e-13 48.2 15.8 1.8e-12 46.7 11.0 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF3439 PF11921.3 KEY67481.1 - 0.36 10.5 10.0 0.86 9.3 6.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TrbI PF03743.9 KEY67482.1 - 5.1 6.5 7.0 2.5 7.5 0.4 2.9 2 1 1 3 3 3 0 Bacterial conjugation TrbI-like protein TPR_14 PF13428.1 KEY67483.1 - 5.5e-23 79.3 16.9 4.7e-05 23.6 0.0 10.1 8 2 2 11 11 10 7 Tetratricopeptide repeat HAT PF02184.11 KEY67483.1 - 4.6e-22 77.4 71.3 5.7e-11 41.9 1.2 13.1 15 0 0 15 15 15 5 HAT (Half-A-TPR) repeat Suf PF05843.9 KEY67483.1 - 2.2e-17 63.6 17.4 2e-05 24.4 1.2 6.2 2 1 1 5 5 5 5 Suppressor of forked protein (Suf) TPR_19 PF14559.1 KEY67483.1 - 7e-17 61.5 0.1 2.1e-05 24.7 0.0 7.4 6 1 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEY67483.1 - 1.4e-14 54.2 17.1 0.033 14.8 0.0 8.5 8 2 2 11 11 11 4 Tetratricopeptide repeat TPR_15 PF13429.1 KEY67483.1 - 1.6e-07 30.6 14.4 0.015 14.3 0.5 5.2 4 1 0 4 4 4 4 Tetratricopeptide repeat U3_assoc_6 PF08640.6 KEY67483.1 - 1.5e-06 27.8 24.1 0.033 13.9 0.9 7.0 4 2 1 6 6 6 4 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 KEY67483.1 - 1.6e-06 27.2 30.4 0.047 12.5 0.2 7.3 4 3 3 7 7 7 4 NRDE-2, necessary for RNA interference TPR_6 PF13174.1 KEY67483.1 - 3.4e-06 27.1 15.1 0.039 14.4 0.0 7.7 8 1 0 8 8 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEY67483.1 - 7.9e-06 25.3 12.5 0.52 10.3 0.0 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEY67483.1 - 8.2e-06 25.6 4.3 1.4 9.3 0.0 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEY67483.1 - 1.8e-05 24.2 9.7 0.12 12.0 0.0 6.4 7 0 0 7 7 7 1 TPR repeat TPR_12 PF13424.1 KEY67483.1 - 2.2e-05 24.3 18.6 1.5 8.8 0.0 8.2 8 2 1 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEY67483.1 - 0.00062 19.3 9.4 10 6.1 0.2 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEY67483.1 - 0.001 18.9 9.7 8.3 6.3 0.2 6.3 7 0 0 7 7 7 1 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 KEY67483.1 - 0.041 13.6 0.3 28 4.8 0.4 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEY67483.1 - 0.091 12.4 3.8 53 3.6 0.4 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Prp31_C PF09785.4 KEY67484.1 - 9.4e-45 152.0 0.6 2.1e-44 150.9 0.4 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 KEY67484.1 - 1.6e-39 134.5 0.2 3.5e-39 133.4 0.1 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KEY67484.1 - 1.7e-19 69.3 0.0 3.5e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain zf-C2H2_4 PF13894.1 KEY67485.1 - 7.7e-06 25.8 7.6 0.0006 19.9 0.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY67485.1 - 9.2e-05 22.5 9.8 0.0036 17.5 0.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KEY67485.1 - 0.003 17.7 1.5 0.003 17.7 1.0 3.5 4 0 0 4 4 4 1 Zinc-finger double domain Integrin_B_tail PF07965.7 KEY67485.1 - 0.024 15.0 0.5 0.047 14.1 0.2 1.5 1 1 0 1 1 1 0 Integrin beta tail domain zf-met PF12874.2 KEY67485.1 - 0.026 14.7 5.6 0.42 10.9 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Ribosomal_S15 PF00312.17 KEY67485.1 - 0.14 11.9 0.4 0.27 11.0 0.3 1.4 1 0 0 1 1 1 0 Ribosomal protein S15 Acetate_kinase PF00871.12 KEY67486.1 - 4.7e-91 305.2 0.0 5.8e-91 304.9 0.0 1.1 1 0 0 1 1 1 1 Acetokinase family Sugar_tr PF00083.19 KEY67488.1 - 4.5e-29 101.3 21.4 6.8e-18 64.4 3.6 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KEY67488.1 - 4.2e-23 81.6 16.4 1e-16 60.6 6.8 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Lysis_S PF04971.7 KEY67488.1 - 0.057 13.1 0.8 0.72 9.5 0.0 2.7 2 0 0 2 2 2 0 Lysis protein S GST_N_3 PF13417.1 KEY67489.1 - 4.3e-21 74.9 0.0 1e-20 73.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEY67489.1 - 4e-14 52.3 0.0 8.3e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEY67489.1 - 0.0011 18.7 0.2 0.0035 17.2 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KEY67489.1 - 0.053 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 KEY67489.1 - 0.081 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin Fungal_trans PF04082.13 KEY67490.1 - 5.7e-20 71.2 0.1 1e-19 70.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY67490.1 - 3.7e-06 26.7 5.2 1.1e-05 25.2 3.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 KEY67491.1 - 7.8e-28 95.3 11.2 8e-09 35.0 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 KEY67491.1 - 0.00014 20.1 0.6 0.0042 15.2 0.3 2.6 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 KEY67491.1 - 0.027 13.9 0.0 0.34 10.4 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.6 KEY67491.1 - 0.027 14.1 0.4 0.57 9.8 0.0 3.0 4 1 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A P2X_receptor PF00864.14 KEY67491.1 - 0.11 11.1 0.1 0.16 10.6 0.1 1.2 1 0 0 1 1 1 0 ATP P2X receptor Cyclin_N PF00134.18 KEY67492.1 - 8.2e-44 148.2 0.1 2.8e-42 143.2 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KEY67492.1 - 1.7e-34 118.2 0.1 3.2e-34 117.3 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ribosomal_L2_C PF03947.13 KEY67493.1 - 1.9e-44 150.5 4.3 1.3e-43 147.9 3.0 2.3 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KEY67493.1 - 2.9e-24 84.8 0.3 5.8e-24 83.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PAP2 PF01569.16 KEY67494.1 - 3e-20 72.2 0.7 1.1e-19 70.4 0.2 2.1 2 1 0 2 2 2 1 PAP2 superfamily Rhomboid PF01694.17 KEY67494.1 - 0.32 11.0 6.7 5.2 7.0 1.1 2.9 2 1 0 2 2 2 0 Rhomboid family CK_II_beta PF01214.13 KEY67495.1 - 9.5e-73 243.6 0.2 1.3e-72 243.1 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RIC1 PF07064.8 KEY67496.1 - 3.7e-84 282.1 0.2 5.1e-84 281.7 0.2 1.2 1 0 0 1 1 1 1 RIC1 Aminotran_1_2 PF00155.16 KEY67497.1 - 3.8e-16 58.9 0.0 5e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KEY67497.1 - 7.5e-07 28.0 0.0 1.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 KEY67497.1 - 0.027 13.5 0.0 1.2 8.0 0.0 2.2 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family p450 PF00067.17 KEY67498.1 - 4.5e-64 216.6 0.0 6.6e-64 216.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_20 PF00728.17 KEY67499.1 - 1.4e-88 297.4 0.0 1.7e-88 297.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 KEY67499.1 - 1e-19 71.4 0.0 1.7e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KEY67499.1 - 2e-06 28.3 0.0 5.5e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 zf-CCCH_2 PF14608.1 KEY67500.1 - 1.5e-12 47.0 54.7 1.8e-06 27.7 7.4 5.4 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 KEY67500.1 - 0.00014 21.9 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Amino_oxidase PF01593.19 KEY67501.1 - 1.7e-17 63.6 0.0 8e-17 61.4 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KEY67501.1 - 5.4e-11 42.3 0.0 1.4e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEY67501.1 - 2.3e-07 30.0 0.0 1.3e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KEY67501.1 - 0.0028 16.7 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KEY67501.1 - 0.01 16.2 0.5 0.31 11.4 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KEY67501.1 - 0.04 12.5 0.0 0.055 12.0 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KEY67501.1 - 0.04 13.6 0.1 0.49 10.1 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KEY67501.1 - 0.11 12.5 0.1 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEY67501.1 - 0.14 12.0 0.0 3.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Med14 PF08638.6 KEY67502.1 - 6.2e-70 234.4 0.2 1.1e-69 233.5 0.2 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 G6PD_C PF02781.11 KEY67503.1 - 3.1e-134 446.4 0.0 4.5e-134 445.9 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KEY67503.1 - 3.7e-63 213.0 0.0 5.9e-63 212.4 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Ribosomal_L35Ae PF01247.13 KEY67504.1 - 3.9e-41 138.7 0.5 4.4e-41 138.5 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KEY67504.1 - 0.00029 20.6 0.0 0.47 10.4 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2406 PF10295.4 KEY67505.1 - 2.9e-19 69.3 1.3 9.6e-19 67.6 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) VMA21 PF09446.5 KEY67506.1 - 1.6e-14 53.5 6.9 2.4e-14 52.9 4.8 1.3 1 0 0 1 1 1 1 VMA21-like domain Claudin_2 PF13903.1 KEY67506.1 - 0.027 14.1 0.0 0.031 13.9 0.0 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF4282 PF14110.1 KEY67506.1 - 0.16 12.1 5.4 0.22 11.7 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) SNF2_N PF00176.18 KEY67507.1 - 5.6e-59 199.3 0.0 8.8e-59 198.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEY67507.1 - 2.3e-12 46.5 0.0 1.2e-11 44.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEY67507.1 - 0.0019 17.7 0.0 0.0054 16.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Amidohydro_2 PF04909.9 KEY67507.1 - 0.07 12.6 0.4 7.7 5.9 0.0 2.7 2 1 1 3 3 3 0 Amidohydrolase Myb_DNA-bind_6 PF13921.1 KEY67508.1 - 0.0087 16.1 0.3 0.02 15.0 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Sel1 PF08238.7 KEY67510.1 - 2.7e-32 110.4 37.3 5.7e-05 23.6 0.5 7.7 7 0 0 7 7 7 7 Sel1 repeat Chitin_synth_2 PF03142.10 KEY67511.1 - 2.6e-290 963.3 0.1 3.5e-290 962.8 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KEY67511.1 - 2.5e-18 66.5 3.3 1.1e-17 64.3 2.3 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KEY67511.1 - 2e-13 50.7 0.0 1.1e-11 45.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 KEY67511.1 - 5.9e-11 42.0 0.1 1.5e-09 37.4 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 KEY67511.1 - 1.5e-05 24.3 0.0 0.00031 20.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KEY67511.1 - 0.0011 18.6 0.0 0.034 13.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Flavi_NS4B PF01349.12 KEY67511.1 - 0.061 12.2 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4B Pkinase PF00069.20 KEY67512.1 - 3.7e-67 226.2 0.0 6.5e-67 225.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY67512.1 - 1.4e-40 139.0 0.0 2.1e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 KEY67512.1 - 4.2e-08 33.0 0.1 5.8e-05 22.9 0.0 3.2 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 KEY67512.1 - 8.3e-08 31.5 0.0 1.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEY67512.1 - 0.00049 19.2 0.0 0.00087 18.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family OPA3 PF07047.7 KEY67513.1 - 3.5e-41 140.1 4.4 2.5e-40 137.3 3.0 2.0 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) AAA_27 PF13514.1 KEY67513.1 - 0.0022 15.7 3.0 0.0022 15.7 2.0 1.8 2 0 0 2 2 2 1 AAA domain Tropomyosin PF00261.15 KEY67513.1 - 0.2 10.7 15.6 0.032 13.3 4.6 2.1 2 0 0 2 2 2 0 Tropomyosin DnaJ PF00226.26 KEY67513.1 - 0.2 11.3 7.8 0.44 10.3 2.0 3.1 2 2 0 2 2 2 0 DnaJ domain Z1 PF10593.4 KEY67513.1 - 0.27 10.4 1.7 0.29 10.3 0.3 1.6 2 0 0 2 2 2 0 Z1 domain ProSAAS PF07259.7 KEY67513.1 - 0.58 9.6 4.0 0.27 10.7 0.3 1.9 2 0 0 2 2 2 0 ProSAAS precursor Ala_racemase_N PF01168.15 KEY67513.1 - 1.1 8.7 6.3 0.4 10.1 0.7 2.2 2 1 0 2 2 2 0 Alanine racemase, N-terminal domain IncA PF04156.9 KEY67513.1 - 1.5 8.3 11.1 0.079 12.5 4.0 1.5 2 0 0 2 2 2 0 IncA protein DUF607 PF04678.8 KEY67513.1 - 1.8 8.4 6.4 1.2 9.0 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF607 Adaptin_binding PF10199.4 KEY67513.1 - 2 8.6 8.2 0.68 10.2 2.0 2.0 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Prefoldin_2 PF01920.15 KEY67513.1 - 2.4 7.9 11.7 0.3 10.8 3.9 2.0 2 0 0 2 2 2 0 Prefoldin subunit DUF4303 PF14136.1 KEY67513.1 - 2.9 7.5 5.5 5.8 6.5 3.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4303) GAS PF13851.1 KEY67513.1 - 3.2 6.9 12.7 0.071 12.2 4.2 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding RmuC PF02646.11 KEY67513.1 - 3.3 6.4 8.6 0.41 9.4 3.2 1.4 2 0 0 2 2 2 0 RmuC family Striatin PF08232.7 KEY67513.1 - 4.3 7.6 11.8 2.4 8.4 3.3 2.1 2 0 0 2 2 2 0 Striatin family V_ATPase_I PF01496.14 KEY67513.1 - 4.4 5.0 7.5 0.7 7.6 2.5 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Ax_dynein_light PF10211.4 KEY67513.1 - 4.9 6.9 12.3 1.4 8.7 4.1 2.0 2 0 0 2 2 2 0 Axonemal dynein light chain ADIP PF11559.3 KEY67513.1 - 8.5 6.2 12.9 0.74 9.7 4.6 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FemAB PF02388.11 KEY67513.1 - 8.6 4.9 9.1 0.95 8.0 1.5 2.0 2 0 0 2 2 2 0 FemAB family SBDS PF01172.13 KEY67516.1 - 8.3e-22 76.7 0.0 9.7e-22 76.5 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RhoGEF PF00621.15 KEY67517.1 - 1.2e-23 83.9 0.0 2.4e-23 82.9 0.0 1.6 1 1 0 1 1 1 1 RhoGEF domain E1-E2_ATPase PF00122.15 KEY67519.1 - 3.3e-65 219.3 7.1 4.8e-64 215.5 3.7 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEY67519.1 - 1.4e-45 155.0 4.9 1.4e-45 155.0 3.4 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEY67519.1 - 3.9e-30 105.8 0.0 7.9e-29 101.6 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEY67519.1 - 8e-23 80.2 0.0 1.5e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KEY67519.1 - 3.5e-20 71.2 0.0 1.1e-19 69.6 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KEY67519.1 - 7e-16 58.9 0.0 2.1e-15 57.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEY67519.1 - 2.7e-08 33.7 0.6 5.3e-06 26.2 0.5 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KEY67519.1 - 0.017 15.3 0.0 0.08 13.1 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Proteasome PF00227.21 KEY67520.1 - 5.9e-37 126.8 0.0 6.6e-37 126.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.3 KEY67521.1 - 5.3e-24 83.9 0.1 9.6e-24 83.0 0.0 1.4 1 0 0 1 1 1 1 GLUT4 regulating protein TUG RBD PF02196.10 KEY67521.1 - 0.00014 21.5 0.1 0.00054 19.6 0.1 1.9 2 0 0 2 2 2 1 Raf-like Ras-binding domain DUF4294 PF14127.1 KEY67521.1 - 0.028 14.0 0.0 0.077 12.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) FERM_N PF09379.5 KEY67521.1 - 0.047 13.7 0.0 3.6 7.6 0.0 3.0 2 1 0 2 2 2 0 FERM N-terminal domain MSA_2 PF00985.12 KEY67521.1 - 0.32 11.1 5.6 0.54 10.3 3.9 1.3 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Ribosomal_L36e PF01158.13 KEY67522.1 - 3.8e-39 132.6 5.6 4.4e-39 132.4 3.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 KEY67522.1 - 0.11 11.6 0.2 0.12 11.4 0.1 1.1 1 0 0 1 1 1 0 LemA family Adhesin_P1 PF03257.8 KEY67523.1 - 0.11 12.7 5.5 1.7 8.9 0.9 2.3 2 0 0 2 2 2 0 Mycoplasma adhesin P1 Lipase_3 PF01764.20 KEY67524.1 - 2e-32 111.7 0.0 2.7e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KEY67524.1 - 3.5e-05 23.8 0.0 0.00012 22.0 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY67524.1 - 0.00016 21.4 0.0 0.00024 20.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KEY67524.1 - 0.0046 16.3 0.0 0.044 13.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Thioesterase PF00975.15 KEY67524.1 - 0.0082 16.3 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.15 KEY67524.1 - 0.053 12.9 0.0 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 Putative esterase PGAP1 PF07819.8 KEY67524.1 - 0.2 11.2 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein 14-3-3 PF00244.15 KEY67525.1 - 1.5e-113 377.6 2.1 1.8e-113 377.4 1.5 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 KEY67525.1 - 0.0069 16.2 0.2 3.4 7.6 0.0 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat DUF837 PF05769.6 KEY67525.1 - 0.027 13.9 0.3 6.1 6.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF837) Ribosomal_60s PF00428.14 KEY67525.1 - 0.25 11.7 12.4 0.12 12.8 4.7 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4597 PF15366.1 KEY67526.1 - 0.1 12.1 0.0 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) Syja_N PF02383.13 KEY67527.1 - 1e-81 274.1 0.0 1.5e-81 273.6 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 KEY67527.1 - 5.4e-24 85.4 0.0 9.5e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Metallophos PF00149.23 KEY67527.1 - 0.071 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase TPR_14 PF13428.1 KEY67528.1 - 4.1e-06 26.9 0.8 17 6.3 0.0 7.1 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEY67528.1 - 4.4e-06 27.1 0.1 0.00026 21.5 0.0 3.7 5 0 0 5 5 5 1 Tetratricopeptide repeat Suf PF05843.9 KEY67528.1 - 2.5e-05 24.1 2.3 0.024 14.3 0.0 3.3 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.5 KEY67528.1 - 0.23 10.3 6.2 0.62 8.8 0.1 3.7 3 1 1 4 4 4 0 NRDE-2, necessary for RNA interference peroxidase PF00141.18 KEY67529.1 - 1.5e-48 165.2 0.0 2.5e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Staph_haemo PF05480.6 KEY67532.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Staphylococcus haemolytic protein Thioredoxin PF00085.15 KEY67533.1 - 7.2e-65 215.2 4.4 5e-30 103.2 0.1 4.1 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 KEY67533.1 - 3.1e-51 173.8 3.5 2.4e-38 131.7 0.3 4.2 3 2 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KEY67533.1 - 9.3e-13 48.0 0.1 2.7e-05 24.1 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.1 KEY67533.1 - 6.8e-11 42.1 0.1 0.00092 19.2 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KEY67533.1 - 5.4e-10 39.4 1.8 0.00053 20.1 0.1 3.8 2 2 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.16 KEY67533.1 - 3.4e-09 36.4 1.8 0.00022 20.9 0.1 3.3 3 0 0 3 3 3 2 AhpC/TSA family Calsequestrin PF01216.12 KEY67533.1 - 6.8e-08 31.6 0.7 1.5e-07 30.5 0.3 1.6 1 1 0 1 1 1 1 Calsequestrin Redoxin PF08534.5 KEY67533.1 - 2e-07 30.6 5.7 0.0016 17.9 0.0 3.5 4 1 0 4 4 4 2 Redoxin ERp29_N PF07912.8 KEY67533.1 - 0.00013 21.9 0.2 0.14 12.0 0.0 3.6 4 0 0 4 4 4 1 ERp29, N-terminal domain Thioredoxin_4 PF13462.1 KEY67533.1 - 0.00091 19.2 5.5 0.28 11.1 0.6 4.2 3 2 1 4 4 4 2 Thioredoxin DUF877 PF05943.7 KEY67533.1 - 0.02 13.4 0.1 0.039 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF877) Ribosomal_60s PF00428.14 KEY67533.1 - 0.77 10.2 15.6 0.15 12.4 7.2 2.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein LPP PF04728.8 KEY67534.1 - 0.026 14.3 0.1 0.039 13.7 0.1 1.3 1 0 0 1 1 1 0 Lipoprotein leucine-zipper zf-HIT PF04438.11 KEY67535.1 - 1.3e-09 37.5 4.8 1.9e-09 36.9 3.3 1.3 1 0 0 1 1 1 1 HIT zinc finger tRNA-synt_2b PF00587.20 KEY67536.1 - 5.3e-43 146.5 0.1 9.7e-43 145.7 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KEY67536.1 - 1.1e-16 60.5 0.2 2.3e-16 59.5 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 KEY67536.1 - 1.1e-12 47.6 0.0 2.5e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 KEY67536.1 - 1.2e-11 44.2 0.0 3.1e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 TGS domain WD40 PF00400.27 KEY67537.1 - 7e-07 28.8 0.2 3.5e-05 23.5 0.0 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF2415 PF10313.4 KEY67537.1 - 0.0005 19.6 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) RNB PF00773.14 KEY67540.1 - 3e-53 181.2 0.0 4.3e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 RNB domain DUF1752 PF08550.5 KEY67541.1 - 1.6e-07 30.7 1.6 4.1e-07 29.4 1.1 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Met_10 PF02475.11 KEY67543.1 - 1.2e-70 237.2 0.0 1.7e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 KEY67543.1 - 0.075 13.6 0.0 0.28 11.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain 2OG-FeII_Oxy_2 PF13532.1 KEY67544.1 - 4.1e-30 105.0 0.0 6.2e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Prenyltransf PF01255.14 KEY67545.1 - 8.2e-09 34.9 0.0 1.7e-08 33.8 0.0 1.5 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase Sec10 PF07393.6 KEY67546.1 - 4.6e-223 742.4 6.4 5.5e-223 742.1 4.4 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Hpt PF01627.18 KEY67546.1 - 0.11 12.5 4.8 0.35 10.8 0.0 3.6 3 0 0 3 3 3 0 Hpt domain FlgN PF05130.7 KEY67546.1 - 2.1 8.5 9.8 0.66 10.2 0.2 4.1 4 1 0 4 4 4 0 FlgN protein Dus PF01207.12 KEY67547.1 - 1.1e-36 126.2 0.0 2.5e-32 111.9 0.0 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) IBR PF01485.16 KEY67548.1 - 6.2e-08 32.3 24.8 7e-06 25.8 9.2 3.2 3 1 0 3 3 3 2 IBR domain FAA_hydrolase PF01557.13 KEY67549.1 - 6e-64 215.4 0.0 7.4e-64 215.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Complex1_LYR PF05347.10 KEY67550.1 - 5e-16 58.2 2.6 6.2e-16 57.9 1.8 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KEY67550.1 - 4.4e-12 46.0 2.9 5e-12 45.8 2.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like PBAN PF05874.6 KEY67550.1 - 0.0098 15.2 0.0 0.01 15.1 0.0 1.1 1 0 0 1 1 1 1 Pheromone biosynthesis activating neuropeptide (PBAN) dDENN PF03455.14 KEY67550.1 - 0.063 13.3 0.1 0.08 13.0 0.1 1.2 1 0 0 1 1 1 0 dDENN domain Complex1_LYR_2 PF13233.1 KEY67550.1 - 0.067 13.6 0.3 0.084 13.3 0.2 1.2 1 0 0 1 1 1 0 Complex1_LYR-like ThiS PF02597.15 KEY67552.1 - 1.8e-11 44.2 0.0 2.5e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 ThiS family Dynamitin PF04912.9 KEY67553.1 - 1.5e-34 119.4 7.4 3.9e-32 111.5 5.1 2.9 1 1 0 1 1 1 1 Dynamitin YkyA PF10368.4 KEY67553.1 - 0.011 15.0 0.5 0.037 13.3 0.1 1.9 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Flagellin_N PF00669.15 KEY67553.1 - 0.011 15.5 5.1 0.041 13.6 0.1 3.1 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region FH2 PF02181.18 KEY67553.1 - 0.016 14.0 0.6 2.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Formin Homology 2 Domain BLOC1_2 PF10046.4 KEY67553.1 - 0.081 13.0 5.0 13 6.0 0.3 4.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF342 PF03961.8 KEY67553.1 - 0.14 10.5 0.9 3.4 5.9 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Tup_N PF08581.5 KEY67553.1 - 0.25 11.5 4.3 53 4.1 0.1 3.5 3 0 0 3 3 3 0 Tup N-terminal Fzo_mitofusin PF04799.8 KEY67553.1 - 0.36 10.2 1.6 6.1 6.2 0.2 2.4 2 0 0 2 2 2 0 fzo-like conserved region Laminin_II PF06009.7 KEY67553.1 - 0.44 10.3 11.8 0.73 9.5 0.4 3.8 3 1 1 4 4 4 0 Laminin Domain II GAS PF13851.1 KEY67553.1 - 0.53 9.4 7.0 1.2 8.3 0.2 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding HWE_HK PF07536.9 KEY67553.1 - 0.57 10.6 7.1 0.24 11.8 0.4 3.5 4 0 0 4 4 4 0 HWE histidine kinase COG2 PF06148.6 KEY67553.1 - 0.89 9.4 7.2 4.8 7.0 0.3 2.9 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.7 KEY67553.1 - 1.2 8.8 13.4 0.19 11.4 0.9 2.8 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Herpes_UL25 PF01499.11 KEY67553.1 - 1.8 6.7 8.1 1.6 6.9 0.1 2.4 3 0 0 3 3 3 0 Herpesvirus UL25 family DUF3450 PF11932.3 KEY67553.1 - 3.6 6.7 11.2 3.3 6.9 0.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Cluap1 PF10234.4 KEY67553.1 - 3.6 6.7 6.5 3.1 6.9 0.5 2.9 3 0 0 3 3 3 0 Clusterin-associated protein-1 DivIC PF04977.10 KEY67553.1 - 5.3 6.6 10.0 4 6.9 0.5 3.2 3 0 0 3 3 3 0 Septum formation initiator CorA PF01544.13 KEY67553.1 - 7.5 5.4 6.0 13 4.7 0.1 2.7 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein RTC4 PF14474.1 KEY67554.1 - 8.2e-27 93.6 0.0 1.7e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain TF_Zn_Ribbon PF08271.7 KEY67554.1 - 0.038 13.2 0.1 0.074 12.3 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Alpha-amylase PF00128.19 KEY67555.1 - 4.6e-100 335.0 0.4 4.6e-100 335.0 0.3 2.1 2 1 0 2 2 2 1 Alpha amylase, catalytic domain DUF3459 PF11941.3 KEY67555.1 - 0.065 13.3 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) adh_short PF00106.20 KEY67557.1 - 4.5e-22 78.7 0.7 7.3e-22 78.0 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY67557.1 - 5.5e-19 68.8 0.1 7.7e-19 68.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY67557.1 - 6e-05 22.7 0.1 0.0001 22.0 0.1 1.3 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.10 KEY67557.1 - 0.015 14.8 0.1 0.025 14.1 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus DUF1028 PF06267.7 KEY67557.1 - 0.023 14.1 0.1 0.19 11.1 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF1028) Glycos_transf_2 PF00535.21 KEY67557.1 - 0.083 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 2 3HCDH_N PF02737.13 KEY67557.1 - 0.11 12.0 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Dak1_2 PF13684.1 KEY67557.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family adh_short PF00106.20 KEY67558.1 - 1.9e-19 70.1 0.1 3.2e-19 69.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY67558.1 - 3.8e-11 42.9 0.2 6.2e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY67558.1 - 8.9e-08 31.8 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KEY67558.1 - 0.01 14.7 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KEY67558.1 - 0.026 14.6 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Phospholip_A2_3 PF09056.6 KEY67559.1 - 3.3e-29 101.3 0.2 5.7e-29 100.5 0.2 1.3 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 tRNA-synt_2 PF00152.15 KEY67560.1 - 3.5e-75 252.8 0.0 2.3e-74 250.1 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KEY67560.1 - 0.00019 21.2 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Cu-oxidase_2 PF07731.9 KEY67562.1 - 2e-38 131.0 6.4 3.6e-37 126.9 0.3 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KEY67562.1 - 2.5e-37 127.1 1.4 2.5e-37 127.1 1.0 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 KEY67562.1 - 3.8e-34 117.8 1.9 3.8e-34 117.8 1.3 2.8 3 1 0 3 3 3 1 Multicopper oxidase DUF3433 PF11915.3 KEY67563.1 - 4.8e-13 49.0 0.7 4.8e-13 49.0 0.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) ATP_synt_I PF03899.10 KEY67563.1 - 0.37 10.9 5.0 0.55 10.4 1.6 2.1 2 0 0 2 2 2 0 ATP synthase I chain SnoaL_4 PF13577.1 KEY67565.1 - 2.5e-08 33.8 0.0 3.5e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain CAP PF00188.21 KEY67566.1 - 9.4e-19 68.1 0.8 1.2e-18 67.7 0.5 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Fungal_trans PF04082.13 KEY67567.1 - 1.7e-17 63.1 0.0 2.8e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KEY67567.1 - 1.6e-08 34.3 12.6 0.0009 19.4 1.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KEY67567.1 - 1.3e-06 28.4 6.4 1.3e-06 28.4 4.4 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KEY67567.1 - 0.0028 17.8 17.4 0.06 13.7 1.9 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 KEY67567.1 - 0.083 13.1 1.3 0.23 11.7 0.9 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KEY67567.1 - 0.11 12.6 3.8 0.41 10.8 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KEY67567.1 - 4.8 7.2 7.2 2.6 8.0 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Arrestin_C PF02752.17 KEY67569.1 - 1.8e-17 63.7 0.1 9.7e-17 61.3 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KEY67569.1 - 1.2e-06 28.4 5.6 0.0013 18.5 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain GTP_EFTU PF00009.22 KEY67570.1 - 3.2e-21 75.6 0.0 5.8e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KEY67570.1 - 3.2e-15 56.0 0.0 9.9e-15 54.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KEY67570.1 - 1.6e-10 40.8 0.7 2.6e-09 37.0 0.2 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Miro PF08477.8 KEY67570.1 - 0.00036 21.0 0.1 0.023 15.1 0.1 3.0 2 1 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KEY67570.1 - 0.0049 16.8 0.1 0.014 15.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 KEY67570.1 - 0.018 14.5 0.5 0.76 9.2 0.1 2.9 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D4 PF14578.1 KEY67570.1 - 0.048 13.3 0.3 0.31 10.6 0.2 2.3 1 1 0 1 1 1 0 Elongation factor Tu domain 4 Dynamin_N PF00350.18 KEY67570.1 - 0.06 13.1 0.1 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Dynamin family LSM PF01423.17 KEY67571.1 - 3.6e-18 64.8 0.2 4.4e-18 64.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain ATP13 PF12921.2 KEY67572.1 - 1e-12 47.4 0.0 1.8e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ATPase expression AAA PF00004.24 KEY67576.1 - 1.2e-07 31.9 0.6 1.5e-06 28.4 0.4 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEY67576.1 - 1.3e-05 25.9 0.0 3.8e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KEY67576.1 - 7.5e-05 21.6 0.1 0.012 14.3 0.0 3.1 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KEY67576.1 - 0.0012 19.0 0.0 0.0038 17.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEY67576.1 - 0.0038 17.2 0.0 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 KEY67576.1 - 0.0083 15.0 0.0 0.016 14.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_18 PF13238.1 KEY67576.1 - 0.013 15.8 0.0 0.043 14.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.8 KEY67576.1 - 0.013 14.2 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_19 PF13245.1 KEY67576.1 - 0.046 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain UPF0079 PF02367.12 KEY67576.1 - 0.073 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 KEY67576.1 - 0.14 12.1 0.0 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KEY67576.1 - 0.15 11.0 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ANTH PF07651.11 KEY67579.1 - 1.3e-67 227.4 0.1 1.7e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 KEY67579.1 - 5.8e-08 32.6 0.0 9.4e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 ENTH domain MAT1 PF06391.8 KEY67580.1 - 8.3e-27 94.0 4.3 1.1e-26 93.6 3.0 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 KEY67580.1 - 0.00022 20.7 6.1 0.00061 19.4 4.3 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEY67580.1 - 0.0012 18.8 8.4 0.0029 17.5 5.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEY67580.1 - 0.0048 16.7 7.2 0.013 15.3 4.9 1.7 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KEY67580.1 - 0.0058 16.2 8.9 0.013 15.1 6.2 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY67580.1 - 0.22 11.3 11.1 2.7 7.7 7.9 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.1 KEY67580.1 - 0.54 9.8 12.5 6.4 6.4 8.7 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain CS PF04969.11 KEY67581.1 - 2.5e-15 56.7 0.2 4.8e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 CS domain LicD PF04991.8 KEY67583.1 - 2.7e-20 73.3 6.9 8.8e-19 68.4 4.8 2.7 1 1 0 1 1 1 1 LicD family ER_lumen_recept PF00810.13 KEY67584.1 - 4.6e-37 127.7 11.6 6.7e-37 127.2 8.0 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KEY67584.1 - 0.00024 20.5 1.9 0.044 13.3 0.0 3.0 2 0 0 2 2 2 2 PQ loop repeat CDC45 PF02724.9 KEY67584.1 - 1.2 7.0 3.4 1.5 6.7 2.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4181 PF13789.1 KEY67584.1 - 5.3 7.0 11.7 2.5 8.0 5.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4181) ADK PF00406.17 KEY67585.1 - 1.5e-35 122.3 0.0 8.2e-19 67.9 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 KEY67585.1 - 2.8e-14 52.4 0.0 5.7e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 KEY67585.1 - 0.00082 19.6 0.0 0.0058 16.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEY67585.1 - 0.0075 17.0 0.0 0.012 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEY67585.1 - 0.019 14.8 0.0 0.4 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain CobT PF06213.7 KEY67586.1 - 0.077 12.1 2.3 0.09 11.8 1.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1275 PF06912.6 KEY67587.1 - 1e-42 145.6 17.9 1.3e-42 145.4 12.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Lactamase_B PF00753.22 KEY67589.1 - 1e-20 74.2 0.5 1.7e-20 73.5 0.3 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KEY67589.1 - 0.0015 18.0 0.1 0.0019 17.7 0.1 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Sulf_transp PF04143.9 KEY67590.1 - 4.3e-14 52.2 27.0 3.9e-09 36.4 7.9 4.8 4 1 0 4 4 4 2 Sulphur transport DUF4341 PF14241.1 KEY67590.1 - 0.0003 20.4 0.5 0.0003 20.4 0.3 4.5 4 1 0 4 4 4 1 Domain of unknown function (DUF4341) Fungal_trans PF04082.13 KEY67591.1 - 5.6e-09 35.2 0.8 1.1e-08 34.2 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY67591.1 - 6.4e-09 35.5 6.9 6.4e-09 35.5 4.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KEY67592.1 - 0.0057 15.8 0.0 0.0066 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LETM1 PF07766.8 KEY67593.1 - 1.1e-103 346.0 0.6 2.7e-103 344.7 0.4 1.7 1 0 0 1 1 1 1 LETM1-like protein PX PF00787.19 KEY67593.1 - 2e-20 72.6 0.4 6.6e-20 70.9 0.3 2.0 1 0 0 1 1 1 1 PX domain BAR PF03114.13 KEY67593.1 - 4.4e-06 26.3 3.0 1.4e-05 24.7 2.1 1.9 1 0 0 1 1 1 1 BAR domain SAP PF02037.22 KEY67593.1 - 2.3e-05 23.7 0.1 0.018 14.5 0.0 3.4 3 0 0 3 3 3 2 SAP domain Vps5 PF09325.5 KEY67593.1 - 0.00036 19.8 6.5 0.0024 17.1 0.8 3.2 3 0 0 3 3 3 2 Vps5 C terminal like DUF3140 PF11338.3 KEY67593.1 - 0.11 12.5 0.2 0.11 12.5 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3140) Peptidase_S8 PF00082.17 KEY67594.1 - 5.3e-57 193.1 2.9 7.7e-57 192.5 2.0 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KEY67594.1 - 1e-29 102.1 0.5 2e-29 101.1 0.4 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain HpaP PF09483.5 KEY67594.1 - 0.0018 18.2 2.8 0.0043 17.0 2.0 1.6 1 0 0 1 1 1 1 Type III secretion protein (HpaP) PepSY_TM_2 PF13703.1 KEY67594.1 - 0.069 13.3 0.2 0.26 11.4 0.1 1.9 1 0 0 1 1 1 0 PepSY-associated TM helix Mito_carr PF00153.22 KEY67595.1 - 4.1e-41 138.5 4.6 3.8e-16 58.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Flu_PB2 PF00604.12 KEY67595.1 - 0.14 9.9 0.0 0.18 9.5 0.0 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB2 Fungal_trans PF04082.13 KEY67596.1 - 0.0012 17.7 0.4 0.0023 16.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY67596.1 - 0.0055 16.5 10.8 0.011 15.6 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tox-WTIP PF15654.1 KEY67596.1 - 0.69 9.5 2.8 1.8 8.2 2.0 1.6 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif NmrA PF05368.8 KEY67597.1 - 3.7e-17 62.3 0.0 5.3e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY67597.1 - 1.5e-12 47.9 0.2 2.2e-12 47.3 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEY67597.1 - 0.0002 20.9 0.0 0.00051 19.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KEY67597.1 - 0.00045 19.9 0.1 0.0012 18.5 0.0 1.8 2 0 0 2 2 2 1 KR domain Saccharop_dh PF03435.13 KEY67597.1 - 0.0014 17.6 0.1 0.002 17.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 KEY67597.1 - 0.0041 17.0 0.5 0.0089 15.9 0.2 1.7 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KEY67597.1 - 0.014 14.1 0.0 0.035 12.8 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 KEY67597.1 - 0.051 13.9 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KEY67597.1 - 0.066 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Zip PF02535.17 KEY67598.1 - 2e-23 82.9 39.8 1.2e-10 40.9 1.8 3.6 3 1 1 4 4 4 3 ZIP Zinc transporter Pectate_lyase PF03211.8 KEY67599.1 - 2.4e-46 157.8 0.2 2.5e-46 157.8 0.2 1.0 1 0 0 1 1 1 1 Pectate lyase gerPA PF10676.4 KEY67599.1 - 0.62 9.9 2.9 0.85 9.5 0.8 1.9 1 1 1 2 2 2 0 Spore germination protein gerPA/gerPF Mnd1 PF03962.10 KEY67600.1 - 0.0085 15.7 5.2 0.0085 15.7 3.6 2.6 3 1 0 3 3 3 1 Mnd1 family Vps5 PF09325.5 KEY67600.1 - 0.055 12.7 8.1 0.035 13.3 3.8 2.1 2 1 0 2 2 2 0 Vps5 C terminal like GAS PF13851.1 KEY67600.1 - 0.092 11.9 11.3 0.24 10.5 7.8 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.7 KEY67600.1 - 0.2 11.4 7.7 0.11 12.2 3.1 2.2 2 0 0 2 2 2 0 Laminin Domain II ASL_C PF08328.6 KEY67600.1 - 0.21 11.4 2.4 7.9 6.3 0.2 3.0 2 1 0 2 2 2 0 Adenylosuccinate lyase C-terminal FliD_N PF02465.13 KEY67600.1 - 0.24 11.7 8.0 0.45 10.9 1.7 2.8 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Atg14 PF10186.4 KEY67600.1 - 0.61 8.9 8.6 1.6 7.6 6.0 1.7 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 COG2 PF06148.6 KEY67600.1 - 1.9 8.3 7.3 3.6 7.4 0.2 3.0 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Seryl_tRNA_N PF02403.17 KEY67600.1 - 4.9 7.2 12.9 3.5 7.6 5.8 2.9 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Occludin_ELL PF07303.8 KEY67600.1 - 6.1 7.6 8.0 3.4 8.4 2.8 2.7 3 1 0 3 3 3 0 Occludin homology domain DUF4600 PF15372.1 KEY67600.1 - 7.9 6.7 12.4 0.043 14.0 1.6 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4600) DUF1664 PF07889.7 KEY67600.1 - 8.3 6.2 7.7 18 5.1 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) p450 PF00067.17 KEY67605.1 - 1.7e-51 175.2 0.0 2.1e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HMG-CoA_red PF00368.13 KEY67606.1 - 3.3e-155 516.3 4.8 4.3e-155 515.9 3.4 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 KEY67606.1 - 1.5e-34 118.9 0.1 2.8e-34 118.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 KEY67606.1 - 2.7e-15 56.1 5.6 1.4e-13 50.5 3.9 2.5 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KEY67606.1 - 1.3e-06 26.6 3.2 2.2e-06 25.9 2.2 1.2 1 0 0 1 1 1 1 Patched family ECIST_Cterm PF14784.1 KEY67606.1 - 0.023 14.6 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein Isochorismatase PF00857.15 KEY67607.1 - 1.1e-27 97.0 0.0 3e-27 95.6 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family DUF202 PF02656.10 KEY67608.1 - 7.2e-23 80.5 4.3 1.7e-22 79.4 0.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF202) AAA_11 PF13086.1 KEY67609.1 - 9.3e-60 202.1 0.5 5.3e-59 199.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KEY67609.1 - 1.4e-54 184.5 0.0 3.5e-54 183.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEY67609.1 - 3.1e-13 49.2 0.1 1.4e-12 47.1 0.0 2.2 2 0 0 2 2 1 1 Part of AAA domain AAA_30 PF13604.1 KEY67609.1 - 1.2e-10 41.2 0.0 1.2e-08 34.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain ResIII PF04851.10 KEY67609.1 - 9.2e-08 32.1 0.0 8.4e-07 28.9 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KEY67609.1 - 1e-06 28.4 0.0 0.53 9.7 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 KEY67609.1 - 1.2e-06 28.0 0.0 2.7e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 KEY67609.1 - 4e-06 26.4 0.0 0.00012 21.6 0.0 2.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 KEY67609.1 - 4.6e-06 25.8 0.0 3.1e-05 23.1 0.0 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 KEY67609.1 - 0.0002 20.3 0.0 0.00036 19.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 KEY67609.1 - 0.00022 21.3 0.1 0.0064 16.6 0.1 2.6 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 KEY67609.1 - 0.00023 20.8 0.1 0.014 15.0 0.0 2.9 2 1 0 2 2 2 1 Helicase Flavi_DEAD PF07652.9 KEY67609.1 - 0.00042 20.1 0.0 0.0017 18.1 0.0 2.0 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_25 PF13481.1 KEY67609.1 - 0.0019 17.6 0.0 0.025 13.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEY67609.1 - 0.0026 17.7 0.0 0.0068 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.11 KEY67609.1 - 0.0035 16.6 0.0 0.022 13.9 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.12 KEY67609.1 - 0.0042 16.5 0.0 0.013 14.9 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein TrwB_AAD_bind PF10412.4 KEY67609.1 - 0.0044 15.6 0.0 0.0084 14.7 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 KEY67609.1 - 0.0067 15.9 0.0 0.019 14.4 0.0 1.8 2 0 0 2 2 2 1 AAA-like domain AAA PF00004.24 KEY67609.1 - 0.01 16.0 0.0 0.064 13.4 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEY67609.1 - 0.017 14.8 0.2 0.094 12.4 0.0 2.3 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Zot PF05707.7 KEY67609.1 - 0.018 14.5 0.0 0.074 12.5 0.0 2.1 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) 4HB_MCP_1 PF12729.2 KEY67609.1 - 0.028 13.7 0.2 0.028 13.7 0.1 1.7 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction FtsK_SpoIIIE PF01580.13 KEY67609.1 - 0.033 13.6 0.0 0.078 12.4 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family MobB PF03205.9 KEY67609.1 - 0.045 13.4 0.0 2.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KEY67609.1 - 0.05 13.9 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 ABC transporter UvrD_C PF13361.1 KEY67609.1 - 0.057 12.8 0.0 23 4.2 0.0 3.2 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.1 KEY67609.1 - 0.07 13.2 0.0 3.7 7.7 0.0 2.9 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_17 PF13207.1 KEY67609.1 - 0.077 13.8 0.1 0.94 10.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF2580 PF10824.3 KEY67610.1 - 0.04 14.2 0.2 0.11 12.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2580) MbeD_MobD PF04899.7 KEY67610.1 - 0.3 10.9 1.2 0.56 10.1 0.1 1.9 2 0 0 2 2 2 0 MbeD/MobD like Peptidase_M3 PF01432.15 KEY67611.1 - 1.6e-120 403.2 0.0 2.2e-120 402.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 MCM PF00493.18 KEY67611.1 - 0.0039 16.0 0.2 0.0072 15.1 0.2 1.5 1 0 0 1 1 1 1 MCM2/3/5 family O-FucT PF10250.4 KEY67611.1 - 0.016 14.3 0.2 0.23 10.5 0.1 2.1 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Peptidase_M50B PF13398.1 KEY67611.1 - 0.017 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase M50B-like ApoO PF09769.4 KEY67612.1 - 6.8e-50 168.8 0.1 1.7e-49 167.5 0.0 1.6 2 0 0 2 2 2 1 Apolipoprotein O Dus PF01207.12 KEY67613.1 - 6.1e-45 153.3 0.2 2e-44 151.6 0.1 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) ATP_bind_2 PF03668.10 KEY67613.1 - 0.13 11.3 0.1 0.18 10.8 0.1 1.1 1 0 0 1 1 1 0 P-loop ATPase protein family Oxysterol_BP PF01237.13 KEY67615.1 - 2.4e-85 286.1 0.0 3e-85 285.8 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein zf-CCCH PF00642.19 KEY67616.1 - 1.7e-08 33.9 18.1 4.6e-07 29.3 1.6 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KEY67616.1 - 6.9e-05 22.6 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEY67616.1 - 0.0034 16.9 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tachystatin_B PF11478.3 KEY67616.1 - 4.5 7.0 9.0 0.4 10.4 1.3 2.6 3 0 0 3 3 3 0 Antimicrobial chitin binding protein tachystatin B ELMO_CED12 PF04727.8 KEY67617.1 - 4.2e-50 169.6 0.0 9.5e-50 168.4 0.0 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 KEY67617.1 - 3.3e-05 23.6 0.6 0.018 14.7 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF3361) PRA1 PF03208.14 KEY67618.1 - 3.9e-38 130.2 1.0 6.4e-38 129.5 0.7 1.2 1 0 0 1 1 1 1 PRA1 family protein IncA PF04156.9 KEY67618.1 - 0.071 12.6 9.9 0.23 11.0 6.9 1.9 1 1 0 1 1 1 0 IncA protein Nucleoplasmin PF03066.10 KEY67618.1 - 1.2 8.6 5.7 0.29 10.6 0.2 2.3 3 0 0 3 3 3 0 Nucleoplasmin PP28 PF10252.4 KEY67618.1 - 1.5 8.8 17.8 4.8 7.2 12.3 1.9 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 UQ_con PF00179.21 KEY67619.1 - 1.5e-31 108.7 0.0 1.8e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KEY67619.1 - 0.034 14.0 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 KEY67619.1 - 0.041 13.5 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 UEV domain HRDC PF00570.18 KEY67619.1 - 0.11 12.2 0.7 0.24 11.1 0.5 1.6 1 0 0 1 1 1 0 HRDC domain Dioxygenase_C PF00775.16 KEY67619.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Dioxygenase Anp1 PF03452.9 KEY67620.1 - 3.3e-111 370.7 0.0 4.2e-111 370.4 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 KEY67620.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 RRM_1 PF00076.17 KEY67621.1 - 2.6e-19 68.6 0.0 4.5e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY67621.1 - 9e-14 51.2 0.0 1.4e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY67621.1 - 1.2e-07 31.4 0.0 1.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KEY67621.1 - 8.5e-06 26.1 9.4 8.5e-06 26.1 6.5 4.3 4 1 1 5 5 5 1 C-terminal duplication domain of Friend of PRMT1 DUF1932 PF09130.6 KEY67622.1 - 1.4e-19 69.6 0.7 2.8e-19 68.6 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.12 KEY67622.1 - 3.4e-09 37.0 0.1 8.9e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KEY67622.1 - 4.3e-07 29.9 0.0 8.1e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KEY67622.1 - 0.00059 19.0 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KEY67622.1 - 0.0021 17.7 0.1 0.0036 16.9 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 KEY67622.1 - 0.0079 15.5 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain PDH PF02153.12 KEY67622.1 - 0.0089 14.9 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase DGC PF08859.6 KEY67622.1 - 0.31 10.9 2.0 0.34 10.7 0.1 2.1 3 0 0 3 3 3 0 DGC domain tRNA-synt_1 PF00133.17 KEY67624.1 - 9.5e-217 720.7 0.5 8.4e-216 717.6 0.4 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KEY67624.1 - 1.7e-30 105.8 1.0 1.7e-30 105.8 0.7 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KEY67624.1 - 4.9e-15 55.0 0.3 9.4e-06 24.5 0.0 4.9 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KEY67624.1 - 2e-14 53.3 0.0 1.9e-10 40.3 0.0 2.9 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 KEY67624.1 - 0.00022 21.2 9.7 0.00022 21.2 6.7 2.9 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm DEAD PF00270.24 KEY67625.1 - 3.7e-41 140.4 0.0 1.9e-40 138.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY67625.1 - 1.6e-25 88.7 1.8 5e-25 87.1 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF2986 PF11661.3 KEY67625.1 - 0.002 18.3 3.2 0.002 18.3 2.3 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2986) ResIII PF04851.10 KEY67625.1 - 0.12 12.2 2.2 0.24 11.1 0.0 2.6 2 2 1 3 3 3 0 Type III restriction enzyme, res subunit DUF3334 PF11813.3 KEY67625.1 - 0.42 10.1 0.0 0.42 10.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3334) D-ser_dehydrat PF14031.1 KEY67626.1 - 0.053 13.7 0.1 0.069 13.3 0.1 1.4 1 1 0 1 1 1 0 Putative serine dehydratase domain zf-CSL PF05207.8 KEY67627.1 - 3.9e-16 58.2 0.8 5.6e-16 57.7 0.6 1.2 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 KEY67627.1 - 2.5e-11 43.1 0.0 3.9e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain 14-3-3 PF00244.15 KEY67628.1 - 3.6e-116 386.2 5.8 4.2e-116 386.0 4.0 1.0 1 0 0 1 1 1 1 14-3-3 protein IATP PF04568.7 KEY67629.1 - 2.1e-21 75.7 0.4 2.4e-21 75.6 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Atg14 PF10186.4 KEY67629.1 - 0.048 12.6 0.2 0.047 12.6 0.2 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3233 PF11557.3 KEY67629.1 - 0.052 12.3 0.0 0.068 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3233) NinG PF05766.7 KEY67629.1 - 0.075 12.7 0.6 0.092 12.4 0.4 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DUF1003 PF06210.6 KEY67629.1 - 0.25 11.2 2.7 0.34 10.8 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Nsp1_C PF05064.8 KEY67630.1 - 4e-38 129.6 3.4 4e-38 129.6 2.3 1.8 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 KEY67630.1 - 1.8e-27 95.8 249.7 1.1e-06 28.7 27.7 7.6 2 1 5 7 7 7 5 Nucleoporin FG repeat region DUF948 PF06103.6 KEY67630.1 - 0.02 14.7 0.5 0.086 12.7 0.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TMCO5 PF14992.1 KEY67630.1 - 0.12 11.5 7.5 0.061 12.4 3.4 1.6 1 1 1 2 2 2 0 TMCO5 family GAS PF13851.1 KEY67630.1 - 0.24 10.5 5.9 3.4 6.7 0.3 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.7 KEY67630.1 - 0.84 9.9 2.4 1.5 9.1 0.1 2.4 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 KEY67630.1 - 2.9 6.2 8.9 11 4.3 2.5 2.0 1 1 1 2 2 2 0 AAA domain ERM PF00769.14 KEY67630.1 - 3.4 7.1 13.0 0.081 12.4 4.1 1.8 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF4201 PF13870.1 KEY67630.1 - 3.8 6.9 7.9 5.2 6.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) WXG100 PF06013.7 KEY67630.1 - 5.2 7.1 9.4 21 5.1 0.7 2.9 2 1 0 2 2 2 0 Proteins of 100 residues with WXG GTP_EFTU PF00009.22 KEY67632.1 - 5.8e-38 130.2 0.0 1e-37 129.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 KEY67632.1 - 9.4e-36 121.7 0.3 2e-35 120.7 0.2 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 KEY67632.1 - 3.5e-09 36.6 0.4 7.6e-09 35.5 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEY67632.1 - 0.0076 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KEY67632.1 - 0.13 12.0 0.7 0.52 10.1 0.1 2.2 2 1 0 3 3 3 0 Dynamin family MARVEL PF01284.18 KEY67633.1 - 0.00026 20.8 6.7 0.00026 20.8 4.6 1.9 1 1 1 2 2 2 1 Membrane-associating domain Claudin_2 PF13903.1 KEY67633.1 - 0.013 15.1 8.3 0.042 13.5 5.7 1.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Peptidase_M56 PF05569.6 KEY67633.1 - 0.025 13.5 2.7 0.043 12.7 1.8 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 Ninjurin PF04923.7 KEY67633.1 - 0.025 14.3 0.3 0.075 12.7 0.0 1.9 1 1 1 2 2 2 0 Ninjurin AMA-1 PF02430.10 KEY67633.1 - 0.074 11.9 0.5 0.12 11.2 0.4 1.2 1 0 0 1 1 1 0 Apical membrane antigen 1 DUF3329 PF11808.3 KEY67633.1 - 0.077 13.0 0.3 0.92 9.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) DEAD PF00270.24 KEY67634.1 - 3.5e-44 150.2 1.9 4.9e-44 149.7 0.8 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY67634.1 - 1e-27 95.7 0.3 6.2e-27 93.2 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEY67634.1 - 0.002 18.0 0.0 0.0039 17.0 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KEY67634.1 - 0.0045 16.6 0.2 0.013 15.1 0.1 1.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEY67634.1 - 0.016 14.9 0.0 0.049 13.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KEY67634.1 - 0.04 14.0 0.1 0.16 12.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.1 KEY67634.1 - 0.068 12.2 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.9 KEY67634.1 - 0.073 12.8 0.1 0.29 10.8 0.1 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain tRNA-synt_1b PF00579.20 KEY67634.1 - 0.083 12.0 0.0 0.29 10.2 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Fanconi_A PF03511.9 KEY67634.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein Cupin_8 PF13621.1 KEY67635.1 - 3.1e-17 62.9 0.0 2.3e-16 60.0 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 KEY67635.1 - 1.7e-10 41.1 0.0 4.7e-10 39.7 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 KEY67635.1 - 6.7e-07 28.9 0.4 6.7e-07 28.9 0.3 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KEY67635.1 - 9.4e-06 25.1 0.4 2.6e-05 23.7 0.3 1.8 1 0 0 1 1 1 1 F-box domain Cupin_4 PF08007.7 KEY67635.1 - 0.039 13.2 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein SNARE_assoc PF09335.6 KEY67636.1 - 4.9e-14 52.5 6.3 4.9e-14 52.5 4.4 2.5 1 1 0 2 2 2 1 SNARE associated Golgi protein DUF1771 PF08590.5 KEY67636.1 - 1.7e-10 40.7 6.9 2.7e-08 33.7 2.0 3.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1771) Smr PF01713.16 KEY67636.1 - 4.9e-09 36.2 0.0 1.3e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.19 KEY67636.1 - 1.9e-06 27.3 3.4 0.0013 18.3 0.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) IncA PF04156.9 KEY67637.1 - 0.023 14.3 0.2 0.089 12.3 0.0 1.8 2 0 0 2 2 2 0 IncA protein Abhydrolase_6 PF12697.2 KEY67638.1 - 1e-12 48.4 2.3 1.1e-11 45.0 1.6 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY67638.1 - 1e-10 41.6 0.0 1.8e-09 37.5 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY67638.1 - 8e-06 25.6 0.0 7.6e-05 22.4 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEY67638.1 - 0.0038 16.4 0.0 0.0077 15.4 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 KEY67638.1 - 0.011 15.1 0.0 0.055 12.8 0.0 1.9 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S28 PF05577.7 KEY67638.1 - 0.011 14.3 0.0 0.018 13.6 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Hydrolase_4 PF12146.3 KEY67638.1 - 0.018 14.8 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase BTB PF00651.26 KEY67639.1 - 1.3e-05 25.1 0.0 3.7e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain DEAD PF00270.24 KEY67640.1 - 2e-17 63.1 0.0 1.1e-16 60.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY67640.1 - 5e-06 26.2 0.0 1.6e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 KEY67640.1 - 2.6e-05 24.2 0.3 0.00015 21.8 0.0 2.5 3 0 0 3 3 3 1 Helix-hairpin-helix domain ResIII PF04851.10 KEY67640.1 - 0.00013 21.8 0.0 0.0013 18.5 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_5 PF07728.9 KEY67640.1 - 0.069 12.8 0.0 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Med22 PF06179.7 KEY67641.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 Surfeit locus protein 5 subunit 22 of Mediator complex PseudoU_synth_1 PF01416.15 KEY67642.1 - 4.3e-21 75.3 0.0 1.1e-09 38.6 0.0 2.5 2 1 0 2 2 2 2 tRNA pseudouridine synthase DUF3357 PF11837.3 KEY67643.1 - 0.00069 19.4 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) Anoctamin PF04547.7 KEY67643.1 - 0.016 13.9 0.0 0.017 13.7 0.0 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF912 PF06024.7 KEY67643.1 - 0.14 12.2 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2592 PF10766.4 KEY67643.1 - 0.19 11.0 1.1 0.28 10.5 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2592) Mucin PF01456.12 KEY67643.1 - 7.8 6.2 8.2 13 5.5 5.7 1.4 1 1 0 1 1 1 0 Mucin-like glycoprotein CHZ PF09649.5 KEY67644.1 - 0.0029 16.8 2.6 0.0063 15.7 1.8 1.5 1 0 0 1 1 1 1 Histone chaperone domain CHZ BAF1_ABF1 PF04684.8 KEY67644.1 - 0.017 13.9 0.4 0.018 13.9 0.3 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor WD40 PF00400.27 KEY67645.1 - 1.5e-56 186.3 22.1 2.4e-11 43.0 0.1 8.2 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 KEY67645.1 - 1.1e-13 50.6 0.4 1.1e-13 50.6 0.3 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KEY67645.1 - 8.1e-12 44.4 0.7 2.5e-11 42.9 0.3 2.0 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.3 KEY67645.1 - 5.1e-10 38.1 1.1 0.0075 14.4 0.0 4.4 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Mito_carr PF00153.22 KEY67646.1 - 4.3e-69 228.2 2.2 1.3e-22 79.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cofilin_ADF PF00241.15 KEY67647.1 - 6.1e-21 74.6 0.0 1.3e-09 37.9 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein WSC PF01822.14 KEY67648.1 - 4.3e-05 23.3 2.9 7.4e-05 22.5 2.0 1.5 1 0 0 1 1 1 1 WSC domain Ribosomal_S7e PF01251.13 KEY67649.1 - 4.1e-83 277.5 0.6 4.6e-83 277.3 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Dynactin_p62 PF05502.8 KEY67650.1 - 1.8e-151 505.2 0.1 2.4e-151 504.7 0.1 1.1 1 0 0 1 1 1 1 Dynactin p62 family EBP PF05241.7 KEY67652.1 - 0.0061 15.5 7.4 0.013 14.5 5.1 1.6 1 1 0 1 1 1 1 Emopamil binding protein DUF924 PF06041.6 KEY67653.1 - 4.8e-50 169.9 0.0 6.4e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) ADH_zinc_N PF00107.21 KEY67654.1 - 5.4e-14 51.8 0.0 8.8e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY67654.1 - 9.3e-11 41.4 0.0 3.3e-10 39.6 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain SnoaL PF07366.7 KEY67655.1 - 0.00046 19.7 0.0 0.00086 18.8 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KEY67655.1 - 0.0036 17.6 0.0 0.01 16.1 0.0 1.8 1 0 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.11 KEY67656.1 - 3.1e-40 137.9 69.6 6.3e-38 130.3 45.5 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KEY67656.1 - 1.4e-10 39.9 25.4 2.3e-10 39.3 17.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.13 KEY67657.1 - 0.37 10.7 14.1 0.67 9.9 9.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KEY67658.1 - 2.9e-53 181.0 0.0 3.8e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PHO4 PF01384.15 KEY67659.1 - 5.2e-100 334.2 18.2 6.1e-100 334.0 12.6 1.0 1 0 0 1 1 1 1 Phosphate transporter family MAT_Alpha1 PF04769.7 KEY67660.1 - 0.039 13.2 0.0 0.055 12.7 0.0 1.1 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 ABC_tran PF00005.22 KEY67661.1 - 6.6e-47 159.2 0.0 3.7e-27 95.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEY67661.1 - 5.8e-29 101.3 27.7 9.3e-24 84.2 7.3 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 KEY67661.1 - 3.7e-11 42.6 0.8 0.0022 17.2 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEY67661.1 - 1.9e-10 41.2 0.0 0.18 11.7 0.0 4.3 4 0 0 4 4 4 4 AAA domain DUF258 PF03193.11 KEY67661.1 - 9.2e-07 28.1 0.2 0.046 12.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KEY67661.1 - 4.2e-06 26.1 0.7 0.077 12.5 0.0 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain T2SE PF00437.15 KEY67661.1 - 1.1e-05 24.4 0.2 0.03 13.2 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 KEY67661.1 - 0.00011 22.1 0.1 0.47 10.4 0.0 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KEY67661.1 - 0.00016 21.1 0.1 0.059 12.8 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.1 KEY67661.1 - 0.00018 21.5 0.2 0.3 11.0 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 KEY67661.1 - 0.00064 19.1 0.0 0.46 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KEY67661.1 - 0.00069 20.1 0.0 0.21 12.0 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 KEY67661.1 - 0.0026 17.8 0.1 1.9 8.6 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KEY67661.1 - 0.0051 17.1 0.5 2.6 8.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KEY67661.1 - 0.0058 16.0 0.5 5.7 6.3 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein SbcCD_C PF13558.1 KEY67661.1 - 0.0061 16.4 0.0 0.82 9.6 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit cobW PF02492.14 KEY67661.1 - 0.011 15.2 0.4 0.6 9.5 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.4 KEY67661.1 - 0.012 14.2 0.0 1.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 KEY67661.1 - 0.013 14.9 1.8 2.7 7.3 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain Dynamin_N PF00350.18 KEY67661.1 - 0.038 13.8 1.8 2.8 7.7 0.2 2.5 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.1 KEY67661.1 - 0.042 13.7 0.0 3 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KEY67661.1 - 0.065 12.9 0.1 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_17 PF13207.1 KEY67661.1 - 0.072 13.9 0.0 3.8 8.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain Dodecin PF07311.7 KEY67661.1 - 0.11 12.6 0.2 0.34 10.9 0.1 1.8 1 0 0 1 1 1 0 Dodecin DUF87 PF01935.12 KEY67661.1 - 0.13 12.0 0.8 1.5 8.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 IIGP PF05049.8 KEY67661.1 - 0.24 10.1 0.4 2 7.1 0.1 2.3 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) Zeta_toxin PF06414.7 KEY67661.1 - 0.24 10.4 0.1 29 3.6 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin UPF0052 PF01933.13 KEY67663.1 - 4.7e-55 187.0 0.0 5.7e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Nucleo_P87 PF07267.6 KEY67664.1 - 0.2 10.3 2.5 0.3 9.7 1.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Beta-lactamase PF00144.19 KEY67665.1 - 1.1e-42 146.2 3.4 1.9e-42 145.4 2.3 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KEY67665.1 - 0.00021 21.0 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) NTF2 PF02136.15 KEY67666.1 - 4.3e-30 104.5 0.0 4.7e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 KEY67666.1 - 0.0036 17.0 0.0 0.0041 16.9 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Ribosomal_L7Ae PF01248.21 KEY67667.1 - 1.7e-21 75.4 0.3 3e-21 74.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KEY67667.1 - 0.0094 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 ATP_bind_3 PF01171.15 KEY67668.1 - 9.6e-19 67.5 0.3 1.6e-18 66.8 0.0 1.5 2 0 0 2 2 2 1 PP-loop family DUF2392 PF10288.4 KEY67668.1 - 4.2e-05 23.8 0.0 9.5e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 KEY67668.1 - 0.0089 14.6 0.0 0.016 13.8 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase RecR PF02132.10 KEY67668.1 - 0.014 14.8 2.2 0.014 14.8 1.6 3.0 4 0 0 4 4 4 0 RecR protein zf-UBR PF02207.15 KEY67668.1 - 0.36 10.5 8.5 0.25 11.0 0.9 2.8 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) DZR PF12773.2 KEY67668.1 - 5.7 6.8 9.3 3.5 7.5 0.2 3.3 3 0 0 3 3 3 0 Double zinc ribbon MOZ_SAS PF01853.13 KEY67670.1 - 1.2e-79 265.9 0.1 1.8e-79 265.3 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 KEY67670.1 - 0.00017 21.2 10.0 0.00017 21.2 6.9 2.2 2 0 0 2 2 2 1 PHD-finger zf-MIZ PF02891.15 KEY67670.1 - 0.027 13.9 2.8 0.059 12.8 1.9 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger PHD_2 PF13831.1 KEY67670.1 - 0.037 13.3 1.9 0.1 11.9 1.3 1.8 1 0 0 1 1 1 0 PHD-finger Nup96 PF12110.3 KEY67671.1 - 6.6e-87 291.3 0.8 9.7e-87 290.7 0.6 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 KEY67671.1 - 8.8e-47 158.4 0.0 1.7e-46 157.5 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 KEY67671.1 - 5.4e-34 116.8 360.9 1.8e-10 41.0 30.7 10.1 3 2 7 10 10 10 8 Nucleoporin FG repeat region EF-hand_7 PF13499.1 KEY67672.1 - 1.5e-21 76.3 4.6 1.6e-11 44.1 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KEY67672.1 - 3.9e-16 57.0 7.8 3.9e-06 25.7 0.5 3.3 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 KEY67672.1 - 1.3e-15 56.7 9.3 4.8e-10 38.8 1.8 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 KEY67672.1 - 1.1e-12 46.7 4.1 4.3e-05 23.0 0.2 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 KEY67672.1 - 3.5e-09 35.5 2.5 3e-05 23.1 0.1 3.5 3 0 0 3 3 3 2 EF hand MACPF PF01823.14 KEY67672.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 MAC/Perforin domain EF-hand_like PF09279.6 KEY67672.1 - 0.1 12.5 0.8 0.26 11.3 0.3 1.8 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Spc7_N PF15402.1 KEY67672.1 - 0.19 9.6 2.7 0.077 10.9 0.4 1.4 2 0 0 2 2 2 0 N-terminus of kinetochore NMS complex subunit Spc7 ENTH PF01417.15 KEY67673.1 - 2.9e-51 172.5 0.1 4.7e-51 171.8 0.1 1.3 1 0 0 1 1 1 1 ENTH domain UIM PF02809.15 KEY67673.1 - 0.0017 17.7 2.3 0.0017 17.7 1.6 2.7 2 0 0 2 2 2 1 Ubiquitin interaction motif DUF4264 PF14084.1 KEY67673.1 - 0.018 14.4 0.1 0.032 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) ANTH PF07651.11 KEY67673.1 - 0.025 13.3 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 ANTH domain VHS PF00790.14 KEY67673.1 - 0.036 13.7 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 VHS domain DUF1510 PF07423.6 KEY67673.1 - 1.1 8.5 13.0 0.22 10.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) AA_permease_2 PF13520.1 KEY67674.1 - 4.5e-66 223.1 35.3 7e-66 222.5 24.4 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEY67674.1 - 7.3e-17 60.8 34.4 2.2e-16 59.2 23.9 1.8 1 1 0 1 1 1 1 Amino acid permease Ni_hydr_CYTB PF01292.15 KEY67674.1 - 0.083 12.2 14.9 0.1 12.0 0.8 3.9 4 1 0 4 4 4 0 Prokaryotic cytochrome b561 Myosin_tail_1 PF01576.14 KEY67675.1 - 0.35 8.5 1.5 3.7 5.1 0.3 2.0 2 0 0 2 2 2 0 Myosin tail Mito_carr PF00153.22 KEY67676.1 - 7.7e-55 182.6 1.0 1.3e-20 72.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RCC1 PF00415.13 KEY67677.1 - 9.4e-22 76.9 0.1 4e-05 23.7 0.0 5.8 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 KEY67677.1 - 6.9e-18 64.6 0.0 8.4e-10 38.6 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 KEY67677.1 - 5.5e-10 39.4 0.3 3.1e-09 37.0 0.1 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) RCC1_2 PF13540.1 KEY67677.1 - 2.7e-05 23.6 1.6 2.7e-05 23.6 1.1 4.4 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 KEY67677.1 - 4.8e-05 23.2 0.3 0.21 11.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KEY67677.1 - 0.00012 22.3 0.0 0.00031 21.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KEY67677.1 - 0.0089 15.7 0.2 0.4 10.5 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 KEY67677.1 - 0.017 15.3 0.3 0.46 10.8 0.0 2.7 1 1 1 2 2 2 0 Ankyrin repeats (many copies) ATG13 PF10033.4 KEY67678.1 - 2e-67 227.0 0.0 3.3e-67 226.3 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 VHS PF00790.14 KEY67679.1 - 1.9e-36 124.7 0.1 4.3e-36 123.6 0.1 1.6 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 KEY67679.1 - 4.7e-16 57.9 0.4 1.3e-15 56.5 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KEY67679.1 - 7.6e-16 57.4 0.1 2e-15 56.1 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KEY67679.1 - 1e-14 53.7 0.0 2e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 KEY67679.1 - 0.018 15.0 1.1 0.055 13.4 0.8 1.8 1 0 0 1 1 1 0 GAT domain TIR PF01582.15 KEY67679.1 - 0.068 12.6 0.3 0.27 10.6 0.2 2.0 2 0 0 2 2 2 0 TIR domain UIM PF02809.15 KEY67679.1 - 0.089 12.4 4.9 0.23 11.1 3.4 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif PEPCK_ATP PF01293.15 KEY67680.1 - 2.5e-212 705.4 0.0 3.3e-212 705.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase SNF2_N PF00176.18 KEY67680.1 - 1.8e-73 246.9 0.0 2.9e-73 246.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEY67680.1 - 2.2e-12 46.6 0.0 5.8e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KEY67680.1 - 0.00042 19.2 0.2 0.019 13.8 0.1 2.6 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_34 PF13872.1 KEY67680.1 - 0.083 11.6 0.0 0.19 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 GTP_EFTU PF00009.22 KEY67681.1 - 1.7e-44 151.4 0.0 3.2e-44 150.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KEY67681.1 - 3.8e-22 78.2 0.1 1e-21 76.9 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KEY67681.1 - 4e-08 33.2 0.4 9.9e-08 31.9 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEY67681.1 - 0.00041 20.2 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ran-binding PF05508.6 KEY67682.1 - 1e-85 287.3 0.0 7.6e-85 284.4 0.0 1.9 1 1 0 1 1 1 1 RanGTP-binding protein Cupin_8 PF13621.1 KEY67684.1 - 2.2e-24 86.3 0.0 2.7e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KEY67684.1 - 0.0056 15.9 0.0 0.0094 15.2 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 KEY67684.1 - 0.073 13.3 0.0 0.18 12.0 0.0 1.8 1 1 0 1 1 1 0 JmjC domain, hydroxylase CK_II_beta PF01214.13 KEY67685.1 - 1.6e-76 255.9 0.0 2.8e-76 255.1 0.0 1.4 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 KEY67685.1 - 0.0056 17.2 7.2 0.0056 17.2 5.0 2.3 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal VirE PF05272.6 KEY67685.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E Pox_Ag35 PF03286.9 KEY67685.1 - 0.31 10.5 4.2 0.17 11.4 1.4 1.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Sporozoite_P67 PF05642.6 KEY67685.1 - 0.52 8.1 1.5 0.68 7.7 1.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3752 PF12572.3 KEY67687.1 - 0.00067 19.8 0.2 1.6 8.8 0.1 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF3752) NQR2_RnfD_RnfE PF03116.10 KEY67687.1 - 0.019 14.1 0.0 27 3.7 0.0 3.0 3 0 0 3 3 3 0 NQR2, RnfD, RnfE family UCH_1 PF13423.1 KEY67688.1 - 3.2e-46 158.1 0.5 2e-25 89.8 0.9 2.2 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 KEY67688.1 - 5.8e-27 94.9 0.0 1e-26 94.1 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Methyltransf_31 PF13847.1 KEY67688.1 - 1.8e-07 30.8 0.0 3.5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY67688.1 - 1.9e-07 31.3 0.0 4.5e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain UCH PF00443.24 KEY67688.1 - 7.2e-07 28.5 0.0 3.5e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Methyltransf_12 PF08242.7 KEY67688.1 - 3.4e-05 24.2 0.0 7.4e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 KEY67688.1 - 0.01 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_11 PF08241.7 KEY67688.1 - 0.022 15.2 0.0 0.054 13.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KEY67688.1 - 0.022 15.3 0.0 0.061 13.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KEY67688.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.13 KEY67690.1 - 3.2e-08 33.3 12.8 4.9e-08 32.7 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY67690.1 - 6.2e-06 25.2 0.0 1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Copper-fist PF00649.13 KEY67691.1 - 1.9e-15 55.7 5.0 1.9e-15 55.7 3.5 4.7 2 2 2 4 4 4 2 Copper fist DNA binding domain ApbA PF02558.11 KEY67692.1 - 7.8e-33 113.0 0.0 1e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KEY67692.1 - 4.8e-24 84.7 0.0 7.8e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal GFO_IDH_MocA PF01408.17 KEY67692.1 - 0.042 14.3 0.1 0.069 13.6 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Pyr_redox PF00070.22 KEY67692.1 - 0.044 14.1 0.0 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HATPase_c PF02518.21 KEY67693.1 - 1.5e-19 69.7 0.3 3.4e-19 68.5 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.21 KEY67693.1 - 8.5e-16 58.4 0.0 2e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 GAF domain Response_reg PF00072.19 KEY67693.1 - 3.7e-15 55.9 0.0 1.3e-14 54.1 0.0 2.0 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KEY67693.1 - 2.8e-13 49.6 0.8 1.2e-12 47.5 0.6 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 KEY67693.1 - 1.8e-09 37.9 0.0 8e-09 35.9 0.0 2.2 2 0 0 2 2 2 1 PAS fold PHY PF00360.15 KEY67693.1 - 9.5e-09 34.6 0.0 2.4e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Phytochrome region PAS_9 PF13426.1 KEY67693.1 - 3.9e-05 23.9 0.0 0.00081 19.7 0.0 2.8 3 0 0 3 3 3 1 PAS domain PAS_3 PF08447.6 KEY67693.1 - 0.056 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 PAS fold ABC_tran PF00005.22 KEY67694.1 - 1.1e-46 158.5 0.5 3.9e-24 85.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KEY67694.1 - 3.6e-24 85.4 46.8 1.9e-12 46.9 13.4 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 KEY67694.1 - 4.7e-22 79.2 2.0 9.6e-09 35.6 0.1 4.3 3 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 KEY67694.1 - 4.9e-12 45.2 1.5 2e-05 24.0 0.2 3.5 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KEY67694.1 - 2.3e-08 34.6 3.0 0.0027 18.0 0.1 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KEY67694.1 - 3e-08 33.1 1.7 0.058 12.6 0.1 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KEY67694.1 - 2.2e-05 24.5 0.3 0.33 10.8 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 KEY67694.1 - 6.4e-05 22.1 0.6 0.27 10.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 KEY67694.1 - 0.0012 18.7 0.0 7.8 6.3 0.0 3.8 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.1 KEY67694.1 - 0.0013 17.8 0.0 0.96 8.4 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 KEY67694.1 - 0.0024 17.3 0.7 1.3 8.3 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 KEY67694.1 - 0.013 15.5 0.1 5.4 7.1 0.1 3.3 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KEY67694.1 - 0.024 13.7 0.3 3.7 6.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.1 KEY67694.1 - 0.029 14.3 0.4 2.9 7.8 0.4 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KEY67694.1 - 0.037 13.7 5.4 2.6 7.8 0.2 3.9 3 0 0 3 3 3 0 Part of AAA domain SRP54 PF00448.17 KEY67694.1 - 0.048 13.0 0.8 8.3 5.7 0.2 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 KEY67694.1 - 0.054 13.0 3.2 5.1 6.6 0.2 3.1 2 1 1 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 KEY67694.1 - 0.073 13.0 0.5 20 5.2 0.0 3.6 3 0 0 3 3 3 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 KEY67694.1 - 0.082 13.0 0.0 11 6.2 0.0 2.8 2 0 0 2 2 2 0 RNA helicase ArgK PF03308.11 KEY67694.1 - 0.11 11.2 0.5 1.4 7.6 0.1 2.2 2 0 0 2 2 2 0 ArgK protein AAA_10 PF12846.2 KEY67694.1 - 0.12 11.7 1.1 10 5.4 0.4 2.5 2 0 0 2 2 2 0 AAA-like domain DUF87 PF01935.12 KEY67694.1 - 0.35 10.6 1.2 24 4.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_13 PF13166.1 KEY67694.1 - 0.78 8.1 0.5 17 3.6 0.0 2.3 3 0 0 3 3 3 0 AAA domain Fungal_trans PF04082.13 KEY67695.1 - 2.2e-11 43.1 0.0 4.4e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY67695.1 - 2.3e-07 30.6 12.3 3.8e-07 29.9 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myb_DNA-bind_6 PF13921.1 KEY67696.1 - 0.001 19.1 0.4 0.001 19.1 0.3 5.4 6 1 0 6 6 6 1 Myb-like DNA-binding domain Arginosuc_synth PF00764.14 KEY67697.1 - 8.9e-128 426.6 0.0 2.7e-82 276.8 0.0 2.0 1 1 1 2 2 2 2 Arginosuccinate synthase Asn_synthase PF00733.16 KEY67697.1 - 0.00045 19.7 0.0 0.00063 19.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 KEY67697.1 - 0.022 14.0 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Hemerythrin PF01814.18 KEY67698.1 - 6.8e-10 39.2 2.6 1e-09 38.6 1.8 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Chal_sti_synt_N PF00195.14 KEY67699.1 - 3e-25 88.7 0.1 4.5e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.10 KEY67699.1 - 8.7e-21 74.4 0.0 1.7e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.7 KEY67699.1 - 6.2e-08 32.0 0.0 9.2e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.5 KEY67699.1 - 0.00026 20.9 0.0 0.0012 18.7 0.0 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 KEY67699.1 - 0.00053 19.5 0.0 0.0015 18.1 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MaoC_dehydratas PF01575.14 KEY67700.1 - 0.084 12.2 0.1 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 MaoC like domain TRAUB PF08164.7 KEY67701.1 - 2.3e-31 107.7 0.3 5.4e-31 106.5 0.2 1.7 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 KEY67701.1 - 1.6e-28 99.4 0.2 1.6e-28 99.4 0.1 2.8 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor ParA PF10609.4 KEY67702.1 - 2.9e-33 113.5 0.5 6.3e-33 112.5 0.3 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KEY67702.1 - 8.2e-15 54.7 0.1 1.2e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KEY67702.1 - 2.1e-07 30.9 0.1 2.3e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_26 PF13500.1 KEY67702.1 - 0.00031 20.4 0.5 0.018 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 KEY67702.1 - 0.00031 19.9 0.0 0.00042 19.4 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 KEY67702.1 - 0.0011 18.0 0.6 0.0095 15.0 0.1 2.3 2 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.13 KEY67702.1 - 0.0086 15.2 0.1 0.43 9.7 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family YhjQ PF06564.7 KEY67702.1 - 0.044 13.1 0.1 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 YhjQ protein AAA_25 PF13481.1 KEY67702.1 - 0.054 12.8 0.4 0.17 11.2 0.3 1.9 1 1 0 1 1 1 0 AAA domain DUF4537 PF15057.1 KEY67703.1 - 0.00069 19.3 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) TCO89 PF10452.4 KEY67704.1 - 0.00065 18.7 0.3 0.00065 18.7 0.2 3.2 3 1 0 3 3 3 2 TORC1 subunit TCO89 ABC1 PF03109.11 KEY67705.1 - 9.1e-25 86.9 0.0 5.1e-15 55.4 0.0 2.9 3 0 0 3 3 3 2 ABC1 family APH PF01636.18 KEY67705.1 - 0.007 16.1 0.0 0.026 14.2 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Cyto_heme_lyase PF01265.12 KEY67706.1 - 1.5e-75 254.1 0.0 1.8e-75 253.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase DbpA PF03880.10 KEY67707.1 - 0.062 12.9 0.1 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 DbpA RNA binding domain RRM_5 PF13893.1 KEY67707.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.13 KEY67709.1 - 4e-18 65.2 1.1 6.6e-18 64.5 0.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY67709.1 - 2.1e-05 24.3 7.3 3.5e-05 23.6 5.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.16 KEY67710.1 - 6.7e-91 304.6 0.0 8e-91 304.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III p450 PF00067.17 KEY67711.1 - 5.4e-41 140.5 0.0 7e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BUD22 PF09073.5 KEY67712.1 - 9.6e-67 225.9 23.7 1.1e-66 225.6 16.4 1.0 1 0 0 1 1 1 1 BUD22 Microtub_bind PF13931.1 KEY67712.1 - 1.6 8.8 6.6 0.31 11.1 0.9 2.4 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding adh_short PF00106.20 KEY67713.1 - 1.1e-13 51.3 0.6 1.1e-13 51.3 0.4 2.3 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY67713.1 - 6.9e-13 48.9 0.0 1.8e-11 44.2 0.0 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY67713.1 - 6.9e-05 22.5 0.1 0.00017 21.3 0.0 1.6 2 0 0 2 2 2 1 KR domain Saccharop_dh PF03435.13 KEY67713.1 - 0.0071 15.3 0.0 0.0097 14.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Mito_carr PF00153.22 KEY67714.1 - 2e-54 181.2 6.0 1.5e-20 72.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tir_receptor_N PF07490.6 KEY67714.1 - 0.17 11.4 1.9 0.33 10.5 1.3 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Rad4 PF03835.10 KEY67715.1 - 5.3e-29 100.4 0.6 1.5e-28 99.0 0.4 1.8 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KEY67715.1 - 7.3e-27 92.9 0.1 1.4e-26 91.9 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KEY67715.1 - 1.9e-21 75.2 0.0 3.9e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KEY67715.1 - 2e-12 47.2 0.3 9.7e-12 45.0 0.2 2.3 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KEY67715.1 - 0.00016 21.8 0.0 0.0007 19.7 0.0 2.1 1 1 0 1 1 1 1 Transglutaminase-like superfamily Daxx PF03344.10 KEY67715.1 - 2.5 6.4 13.3 4.3 5.7 9.2 1.2 1 0 0 1 1 1 0 Daxx Family RRM_1 PF00076.17 KEY67717.1 - 7.8e-10 38.2 0.0 1.7e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY67717.1 - 8.9e-09 35.2 0.0 1.6e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEY67717.1 - 0.00052 19.7 0.0 0.0012 18.5 0.0 1.6 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 KEY67717.1 - 0.00098 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAP1 PF08601.5 KEY67717.1 - 0.011 15.4 0.6 0.014 15.0 0.4 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 FoP_duplication PF13865.1 KEY67718.1 - 0.057 13.8 0.3 0.075 13.4 0.2 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Protocadherin PF08374.6 KEY67719.1 - 1.1 8.8 5.7 0.17 11.4 1.5 1.5 2 0 0 2 2 2 0 Protocadherin Striatin PF08232.7 KEY67720.1 - 0.00077 19.7 2.0 0.052 13.8 0.0 2.4 2 0 0 2 2 2 2 Striatin family DUF2051 PF09738.4 KEY67720.1 - 0.52 9.5 6.8 3.2 6.9 1.1 2.3 2 0 0 2 2 2 0 Double stranded RNA binding protein (DUF2051) Myosin_tail_1 PF01576.14 KEY67721.1 - 3.2e-06 25.1 80.9 3.2e-06 25.1 56.1 3.7 3 1 0 3 3 3 2 Myosin tail GAS PF13851.1 KEY67721.1 - 0.0014 17.8 18.3 0.0014 17.8 12.7 7.3 3 1 4 7 7 7 3 Growth-arrest specific micro-tubule binding CCDC155 PF14662.1 KEY67721.1 - 0.002 17.7 3.4 0.002 17.7 2.3 7.5 2 1 4 7 7 7 3 Coiled-coil region of CCDC155 Cluap1 PF10234.4 KEY67721.1 - 0.0028 16.8 6.5 0.0028 16.8 4.5 7.1 3 1 4 7 7 7 1 Clusterin-associated protein-1 DUF1664 PF07889.7 KEY67721.1 - 0.0062 16.3 2.1 0.0062 16.3 1.4 7.8 4 2 3 8 8 8 4 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 KEY67721.1 - 0.031 13.4 49.2 0.96 8.5 2.7 5.8 1 1 4 6 6 6 0 Reovirus sigma C capsid protein ATG16 PF08614.6 KEY67721.1 - 0.29 10.9 96.7 0.59 9.9 8.0 8.3 3 1 6 9 9 9 0 Autophagy protein 16 (ATG16) DASH_Dad4 PF08650.5 KEY67721.1 - 0.57 10.1 8.2 23 4.9 0.2 5.8 5 2 2 7 7 7 0 DASH complex subunit Dad4 DUF2353 PF09789.4 KEY67721.1 - 1.6 7.9 67.6 0.25 10.5 9.3 5.9 2 1 3 5 5 5 0 Uncharacterized coiled-coil protein (DUF2353) IncA PF04156.9 KEY67721.1 - 2.4 7.7 92.8 3.7 7.1 4.9 7.9 3 1 4 7 7 7 0 IncA protein CCDC92 PF14916.1 KEY67721.1 - 4.7 6.8 15.7 0.065 12.8 3.5 3.8 4 0 0 4 4 4 0 Coiled-coil domain of unknown function EzrA PF06160.7 KEY67721.1 - 7.7 4.5 63.0 0.12 10.5 7.3 5.1 2 2 1 4 4 4 0 Septation ring formation regulator, EzrA PWI PF01480.12 KEY67722.1 - 0.0045 17.0 0.0 0.008 16.2 0.0 1.3 1 0 0 1 1 1 1 PWI domain DUF2862 PF11061.3 KEY67722.1 - 0.034 13.8 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) HgmA PF04209.8 KEY67724.1 - 7.3e-174 578.1 0.0 8.4e-174 577.9 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase NMN_transporter PF04973.7 KEY67726.1 - 0.031 13.7 2.4 0.086 12.2 1.7 1.7 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter UQ_con PF00179.21 KEY67728.1 - 3.9e-26 91.1 0.1 5.4e-26 90.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KEY67728.1 - 0.16 11.9 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 RWD domain Bac_surface_Ag PF01103.18 KEY67729.1 - 5e-38 131.3 0.0 6.2e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Surface antigen ABC2_membrane PF01061.19 KEY67730.1 - 1.8e-94 314.7 53.4 2e-48 164.3 13.5 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 KEY67730.1 - 9.9e-34 116.5 0.0 1.8e-16 60.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KEY67730.1 - 2.5e-28 97.7 9.9 5.7e-26 90.1 0.0 3.8 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.1 KEY67730.1 - 4.9e-21 74.6 0.0 1.7e-20 72.8 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KEY67730.1 - 1.1e-07 31.5 0.1 0.00022 20.7 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEY67730.1 - 1.9e-06 27.9 0.1 0.00012 22.1 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_33 PF13671.1 KEY67730.1 - 1.3e-05 25.0 0.0 0.0062 16.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEY67730.1 - 2.1e-05 23.9 0.3 0.0088 15.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 KEY67730.1 - 3.9e-05 22.9 0.0 0.0031 16.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 KEY67730.1 - 0.00021 20.7 0.3 0.0035 16.8 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KEY67730.1 - 0.0012 18.9 0.2 0.26 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 KEY67730.1 - 0.0024 16.9 15.3 0.0024 16.9 10.6 4.3 3 2 1 4 4 4 1 ABC-2 family transporter protein AAA_17 PF13207.1 KEY67730.1 - 0.0072 17.1 0.0 0.39 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEY67730.1 - 0.01 16.1 0.0 0.39 11.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KEY67730.1 - 0.02 14.5 0.5 2.6 7.6 0.0 2.9 3 0 0 3 3 2 0 NACHT domain AAA_19 PF13245.1 KEY67730.1 - 0.02 14.6 0.0 9.9 5.9 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain AAA_21 PF13304.1 KEY67730.1 - 0.021 14.8 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KEY67730.1 - 0.025 13.7 0.0 7.4 5.7 0.0 3.3 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 KEY67730.1 - 0.066 12.8 0.2 2.7 7.6 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 KEY67730.1 - 0.14 12.3 0.0 17 5.5 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KEY67730.1 - 0.15 10.8 0.0 1.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF1072 PF06380.6 KEY67730.1 - 0.26 10.9 2.6 0.3 10.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) AAA_23 PF13476.1 KEY67730.1 - 0.27 11.5 0.1 1.1 9.5 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_15 PF13175.1 KEY67730.1 - 0.73 8.8 0.0 2.2 7.2 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 KEY67730.1 - 0.84 9.0 2.3 15 4.8 0.1 2.6 2 0 0 2 2 2 0 AAA-like domain HET PF06985.6 KEY67735.1 - 2.6e-08 34.1 0.1 1.2e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) GMC_oxred_N PF00732.14 KEY67736.1 - 9e-59 199.0 0.0 1.1e-58 198.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY67736.1 - 2.5e-27 95.9 0.0 3.9e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KEY67736.1 - 4.9e-06 25.6 0.5 0.0016 17.4 0.0 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY67736.1 - 6.1e-05 22.9 0.1 0.00022 21.1 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KEY67736.1 - 0.00037 19.6 0.0 0.001 18.1 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 KEY67736.1 - 0.0012 17.8 0.1 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEY67736.1 - 0.008 16.0 0.0 0.033 14.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY67736.1 - 0.012 15.7 0.0 0.73 9.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEY67736.1 - 0.012 14.5 0.1 0.022 13.5 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 KEY67736.1 - 0.028 14.1 0.2 0.15 11.8 0.0 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding TrkA_N PF02254.13 KEY67736.1 - 0.046 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.22 KEY67736.1 - 0.07 13.5 0.1 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEY67736.1 - 0.12 10.7 0.0 0.21 10.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein 7TM_GPCR_Srh PF10318.4 KEY67737.1 - 0.27 9.9 11.8 0.25 10.1 7.2 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh DUF4231 PF14015.1 KEY67737.1 - 0.89 9.5 4.2 2.4 8.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Abhydrolase_6 PF12697.2 KEY67738.1 - 0.0018 18.2 0.1 0.0026 17.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family adh_short PF00106.20 KEY67739.1 - 2.8e-18 66.4 0.4 4.5e-18 65.7 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY67739.1 - 2.6e-11 43.7 0.0 3.1e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY67739.1 - 1.9e-08 34.1 0.1 3.1e-08 33.4 0.1 1.4 1 1 0 1 1 1 1 KR domain DUF460 PF04312.8 KEY67739.1 - 7e-05 22.3 0.0 0.00015 21.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF460) Permease PF02405.11 KEY67739.1 - 0.11 12.0 0.2 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Permease Aldo_ket_red PF00248.16 KEY67740.1 - 7.8e-64 215.2 0.0 9.8e-64 214.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans_2 PF11951.3 KEY67741.1 - 2.3e-09 36.3 5.5 3.6e-09 35.6 3.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY67741.1 - 0.00011 22.0 2.8 0.00011 22.0 1.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.1 KEY67742.1 - 2.9e-17 62.3 27.6 3.3e-07 30.1 1.5 6.1 4 1 1 6 6 6 5 Tetratricopeptide repeat Patatin PF01734.17 KEY67742.1 - 1.5e-16 60.9 0.0 4.9e-16 59.2 0.0 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_10 PF13374.1 KEY67742.1 - 2e-13 49.7 26.0 6.4e-05 22.7 0.2 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat NB-ARC PF00931.17 KEY67742.1 - 1.5e-12 46.9 0.0 2.5e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_11 PF13414.1 KEY67742.1 - 7.9e-09 35.0 17.3 0.0018 17.8 0.6 5.0 5 0 0 5 5 5 3 TPR repeat Apc3 PF12895.2 KEY67742.1 - 2.2e-08 34.1 10.4 0.0066 16.5 1.9 5.1 1 1 4 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KEY67742.1 - 8.1e-08 32.2 21.9 0.54 11.0 0.0 8.2 6 2 3 9 9 8 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEY67742.1 - 3.9e-07 29.4 18.3 0.62 10.1 0.3 8.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEY67742.1 - 7.4e-07 28.4 9.7 0.095 12.5 0.1 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEY67742.1 - 9.8e-06 26.1 19.2 0.0021 18.6 0.0 5.6 5 1 1 6 6 5 2 Tetratricopeptide repeat AAA_22 PF13401.1 KEY67742.1 - 1.3e-05 25.2 1.2 0.008 16.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEY67742.1 - 1.8e-05 24.8 0.4 1.8e-05 24.8 0.3 3.8 3 2 0 3 3 3 1 AAA ATPase domain TPR_19 PF14559.1 KEY67742.1 - 1.8e-05 24.9 22.7 0.1 12.9 0.2 6.4 4 2 3 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEY67742.1 - 1.8e-05 24.8 26.1 0.16 12.4 0.1 9.0 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEY67742.1 - 4.5e-05 22.8 7.7 2.2 8.0 0.1 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat IstB_IS21 PF01695.12 KEY67742.1 - 0.00033 20.1 0.0 0.001 18.5 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein SRP54 PF00448.17 KEY67742.1 - 0.0011 18.4 0.3 0.0056 16.1 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain PPR PF01535.15 KEY67742.1 - 0.0039 17.0 0.2 38 4.5 0.0 5.0 5 0 0 5 5 4 0 PPR repeat TPR_8 PF13181.1 KEY67742.1 - 0.0054 16.4 9.0 5.7 6.9 0.1 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat Foie-gras_1 PF11817.3 KEY67742.1 - 0.0085 15.5 7.5 1.7 8.0 0.3 3.6 1 1 2 3 3 3 2 Foie gras liver health family 1 NACHT PF05729.7 KEY67742.1 - 0.015 14.9 0.1 0.052 13.1 0.0 2.0 2 0 0 2 2 1 0 NACHT domain AAA PF00004.24 KEY67742.1 - 0.091 12.9 0.1 0.36 11.0 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Glyco_hydro_18 PF00704.23 KEY67743.1 - 4e-43 148.1 0.5 4.7e-43 147.9 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AAA_31 PF13614.1 KEY67743.1 - 0.08 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.19 KEY67745.1 - 2.9e-07 30.4 0.1 1.2e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEY67745.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEY67745.1 - 0.017 14.9 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 KEY67746.1 - 7e-52 176.2 14.8 7e-52 176.2 10.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY67746.1 - 6.8e-09 34.8 11.0 6.8e-09 34.8 7.6 3.1 2 2 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KEY67746.1 - 9.6e-07 27.3 6.1 1.7e-06 26.5 4.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KEY67746.1 - 0.0031 15.7 5.7 0.0031 15.7 4.0 1.5 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_1_like PF12832.2 KEY67746.1 - 0.0073 16.0 4.3 2.1 8.1 0.6 3.4 3 0 0 3 3 3 2 MFS_1 like family ATG22 PF11700.3 KEY67746.1 - 0.07 11.5 16.6 0.03 12.7 0.3 2.7 2 1 1 3 3 3 0 Vacuole effluxer Atg22 like DUF3353 PF11833.3 KEY67746.1 - 1.3 8.4 5.8 14 5.0 3.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) p450 PF00067.17 KEY67747.1 - 3.2e-50 171.0 0.0 5.7e-50 170.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 DUF2165 PF09933.4 KEY67747.1 - 0.064 12.9 0.5 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Predicted small integral membrane protein (DUF2165) PTR2 PF00854.16 KEY67748.1 - 1.1e-42 146.2 10.9 6.8e-26 90.9 1.9 2.5 2 1 1 3 3 3 2 POT family MFS_1 PF07690.11 KEY67748.1 - 6.9e-06 25.0 28.8 0.00043 19.1 19.5 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily Peptidase_M14 PF00246.19 KEY67749.1 - 2.5e-18 66.6 0.0 7.9e-18 65.0 0.0 1.8 1 1 0 1 1 1 1 Zinc carboxypeptidase WSC PF01822.14 KEY67750.1 - 4.3e-16 58.5 4.6 7e-16 57.9 3.2 1.3 1 0 0 1 1 1 1 WSC domain PAN_3 PF08277.7 KEY67750.1 - 0.018 14.6 0.2 0.038 13.6 0.1 1.5 1 0 0 1 1 1 0 PAN-like domain Hydrolase PF00702.21 KEY67751.1 - 1.9e-22 80.7 0.0 1.2e-21 78.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEY67751.1 - 7e-21 75.2 0.0 1.4e-20 74.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KEY67751.1 - 8.3e-20 70.8 0.0 2.1e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KEY67751.1 - 1.4e-05 24.9 0.0 8.2e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEY67751.1 - 0.018 14.5 0.0 0.085 12.4 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ldh_1_N PF00056.18 KEY67752.1 - 5e-43 146.2 0.1 4.2e-42 143.2 0.0 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KEY67752.1 - 9e-43 145.9 0.0 1.3e-42 145.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KEY67752.1 - 0.0013 17.5 0.0 0.0018 17.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family zf-C2HC5 PF06221.8 KEY67753.1 - 1.3e-22 79.3 4.4 2e-22 78.7 3.0 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type FYVE PF01363.16 KEY67753.1 - 0.083 12.7 1.4 0.15 11.9 1.0 1.4 1 0 0 1 1 1 0 FYVE zinc finger ASFV_J13L PF05568.6 KEY67753.1 - 2.6 7.5 8.2 5.1 6.5 5.7 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Whi5 PF08528.6 KEY67754.1 - 4.5e-09 35.6 0.0 7.4e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Whi5 like HET PF06985.6 KEY67756.1 - 3.9e-26 91.8 0.2 7.4e-26 90.9 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Intimin_C PF07979.6 KEY67756.1 - 0.075 13.2 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Intimin C-type lectin domain VWA_2 PF13519.1 KEY67757.1 - 2e-09 37.8 0.1 1.2e-05 25.5 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA PF00092.23 KEY67757.1 - 0.00014 21.6 0.0 0.0028 17.3 0.0 2.6 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 KEY67757.1 - 0.0014 17.7 0.0 1.3 8.1 0.0 2.5 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein Myb_DNA-bind_5 PF13873.1 KEY67757.1 - 0.13 12.1 0.0 0.67 9.8 0.0 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Peptidase_C1 PF00112.18 KEY67757.1 - 0.14 12.0 0.1 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 Papain family cysteine protease Pro-kuma_activ PF09286.6 KEY67758.1 - 1.9e-22 79.8 0.0 3.9e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KEY67758.1 - 2.3e-09 36.8 1.0 3e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 Subtilase family SIR2 PF02146.12 KEY67759.1 - 1.2e-32 113.0 0.1 9.7e-11 41.7 0.0 3.3 3 0 0 3 3 3 3 Sir2 family TraG-D_C PF12696.2 KEY67759.1 - 0.33 10.8 2.2 0.37 10.6 0.1 2.1 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG RAP1 PF07218.6 KEY67759.1 - 5.4 4.9 3.7 9.5 4.1 2.6 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ADH_N PF08240.7 KEY67760.1 - 5.7e-09 35.7 0.1 2.7e-08 33.5 0.1 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Aminotran_5 PF00266.14 KEY67761.1 - 7.4e-22 77.5 0.0 1.3e-21 76.7 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V NAD_binding_8 PF13450.1 KEY67763.1 - 9.5e-10 38.3 0.3 2.2e-09 37.1 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEY67763.1 - 1.7e-08 33.7 1.1 3.1e-08 32.8 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEY67763.1 - 5.8e-07 28.7 0.4 1.3e-06 27.6 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KEY67763.1 - 1.3e-05 23.8 0.6 2.2e-05 23.1 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 KEY67763.1 - 7.7e-05 21.9 2.7 0.00014 21.1 1.9 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEY67763.1 - 0.00011 22.3 0.2 0.00064 19.8 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEY67763.1 - 0.00018 20.6 0.6 0.00027 20.1 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KEY67763.1 - 0.00031 20.6 0.3 0.00081 19.3 0.3 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY67763.1 - 0.0018 18.6 0.5 0.0038 17.5 0.1 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEY67763.1 - 0.004 16.2 0.1 0.011 14.8 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 KEY67763.1 - 0.01 14.7 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 KEY67763.1 - 0.018 13.9 0.2 0.026 13.3 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A IlvN PF07991.7 KEY67763.1 - 0.036 13.4 0.2 0.094 12.0 0.1 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Strep_67kDa_ant PF06100.6 KEY67763.1 - 0.17 10.1 0.0 0.25 9.6 0.0 1.1 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Trp_halogenase PF04820.9 KEY67763.1 - 0.18 10.4 1.4 0.32 9.5 1.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Beta-lactamase PF00144.19 KEY67764.1 - 8.8e-44 149.8 0.0 1.4e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KEY67764.1 - 9.7e-11 41.4 0.1 1.7e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Beta-lactamase2 PF13354.1 KEY67764.1 - 0.018 14.4 0.0 0.11 11.9 0.0 2.2 3 0 0 3 3 3 0 Beta-lactamase enzyme family Pkip-1 PF06878.6 KEY67764.1 - 0.028 14.3 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Pkip-1 protein Glutaminase PF04960.10 KEY67765.1 - 4.1e-100 334.4 0.4 5e-100 334.1 0.3 1.1 1 0 0 1 1 1 1 Glutaminase Sugar_tr PF00083.19 KEY67767.1 - 5.3e-101 338.4 20.3 6.6e-101 338.0 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY67767.1 - 4.9e-28 97.8 14.9 4.9e-28 97.8 10.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Epimerase PF01370.16 KEY67768.1 - 2.1e-16 60.0 0.0 5.5e-16 58.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEY67768.1 - 1.9e-14 53.0 0.0 3.3e-14 52.2 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KEY67768.1 - 4.3e-14 52.9 0.2 1.1e-13 51.6 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KEY67768.1 - 1.3e-10 40.6 0.1 0.00013 20.9 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 KEY67768.1 - 2.8e-08 33.2 0.4 4.7e-07 29.2 0.4 2.1 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 KEY67768.1 - 1.9e-07 31.1 0.4 3.5e-07 30.2 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KEY67768.1 - 1.5e-05 24.0 0.3 2.2e-05 23.5 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KEY67768.1 - 2.3e-05 24.1 0.1 5.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 KEY67768.1 - 0.01 14.7 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DXP_reductoisom PF02670.11 KEY67768.1 - 0.017 15.6 0.4 0.033 14.7 0.3 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase ADH_N PF08240.7 KEY67769.1 - 2.8e-26 91.4 2.4 4.2e-26 90.8 1.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY67769.1 - 1e-12 47.7 0.0 1.6e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KEY67769.1 - 0.002 17.2 0.2 0.0036 16.4 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Y_Y_Y PF07495.8 KEY67769.1 - 0.016 14.9 0.1 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Y_Y_Y domain APH PF01636.18 KEY67771.1 - 9.6e-13 48.4 0.0 3.5e-12 46.5 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEY67771.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fungal_trans PF04082.13 KEY67772.1 - 1.8e-11 43.4 3.8 2.6e-11 42.8 2.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY67772.1 - 1.7e-06 27.8 4.5 2.9e-06 27.0 3.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.1 KEY67773.1 - 4.5e-12 45.9 0.1 1e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KEY67773.1 - 9.5e-10 38.8 0.0 1.8e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KEY67773.1 - 1.1e-05 25.3 0.0 2.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DHDPS PF00701.17 KEY67774.1 - 7.7e-36 123.1 0.0 1.3e-35 122.3 0.0 1.3 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family DdrB PF12747.2 KEY67774.1 - 0.13 12.0 0.0 0.35 10.5 0.0 1.6 2 0 0 2 2 2 0 DdrB-like protein Kelch_6 PF13964.1 KEY67775.1 - 1.1e-05 25.3 0.7 0.066 13.4 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Herpes_gE PF02480.11 KEY67775.1 - 0.00023 19.5 0.0 0.0004 18.7 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Romo1 PF10247.4 KEY67775.1 - 0.032 14.4 0.6 0.076 13.2 0.1 1.8 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 DUF1049 PF06305.6 KEY67775.1 - 0.15 11.5 0.1 0.37 10.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Kelch_5 PF13854.1 KEY67775.1 - 0.42 10.6 8.0 19 5.3 0.0 5.0 5 0 0 5 5 5 0 Kelch motif Kelch_4 PF13418.1 KEY67775.1 - 9.5 6.0 9.2 1.5 8.6 0.1 3.9 4 1 0 4 4 4 0 Galactose oxidase, central domain DUF2157 PF09925.4 KEY67776.1 - 0.0053 16.3 0.7 0.0072 15.9 0.5 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2157) TMEM213 PF15192.1 KEY67776.1 - 0.14 12.1 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 TMEM213 family DUF3487 PF11990.3 KEY67776.1 - 5.1 6.5 7.4 4.4 6.7 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF454 PF04304.8 KEY67776.1 - 9.4 6.3 10.7 2.9 7.9 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF454) Tyrosinase PF00264.15 KEY67777.1 - 8.5e-46 156.8 0.0 1.2e-45 156.4 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Glyco_hydro_43 PF04616.9 KEY67778.1 - 2.6e-46 158.0 2.5 3.4e-46 157.6 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 KEY67778.1 - 2.6e-37 127.7 4.9 2.6e-37 127.7 3.4 2.0 2 0 0 2 2 2 1 Carbohydrate binding module (family 6) CBM_1 PF00734.13 KEY67778.1 - 3.7e-09 36.0 17.1 3.7e-09 36.0 11.8 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_32N PF00251.15 KEY67778.1 - 0.39 10.0 3.4 0.75 9.0 2.4 1.5 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain Toxin_7 PF05980.7 KEY67778.1 - 0.71 9.9 7.1 2.2 8.3 4.9 1.9 1 0 0 1 1 1 0 Toxin 7 APH PF01636.18 KEY67779.1 - 1.4e-12 47.8 0.0 2e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KEY67779.1 - 0.0068 15.0 0.0 0.52 8.8 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 KEY67779.1 - 0.14 11.7 0.1 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ank_2 PF12796.2 KEY67781.1 - 0.00016 21.9 0.0 0.00029 21.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Imm29 PF15575.1 KEY67781.1 - 0.056 13.0 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 29 Ank_4 PF13637.1 KEY67781.1 - 0.14 12.6 0.0 0.41 11.2 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Peptidase_M36 PF02128.10 KEY67782.1 - 4.5e-139 463.4 0.0 5.8e-139 463.1 0.0 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 KEY67782.1 - 1.1e-09 37.6 3.7 2.9e-09 36.2 2.6 1.8 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_MA_2 PF13485.1 KEY67782.1 - 0.002 18.1 1.9 0.0029 17.6 0.0 2.3 3 0 0 3 3 3 1 Peptidase MA superfamily TIM PF00121.13 KEY67786.1 - 1.1e-50 172.0 0.0 1.3e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase Glyco_hydro_3 PF00933.16 KEY67788.1 - 1.5e-80 270.3 0.0 2.1e-80 269.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY67788.1 - 1.8e-55 187.9 0.9 2.9e-55 187.2 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEY67788.1 - 6.6e-26 90.0 0.0 1.4e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Asp PF00026.18 KEY67790.1 - 2e-62 211.3 0.1 2.3e-62 211.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEY67790.1 - 8e-06 25.8 0.0 5.1e-05 23.2 0.0 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KEY67790.1 - 5.5e-05 23.5 1.7 0.0006 20.2 0.2 2.7 2 1 0 2 2 2 1 Aspartyl protease VP4_haemagglut PF00426.13 KEY67791.1 - 2.3 6.0 5.8 2.7 5.8 4.0 1.1 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) FAD_binding_4 PF01565.18 KEY67792.1 - 2.6e-24 85.2 1.3 1e-23 83.3 0.5 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KEY67792.1 - 1e-09 38.1 0.0 2e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Ank_2 PF12796.2 KEY67793.1 - 3.3e-58 194.0 6.5 8.3e-14 51.6 0.4 7.2 6 1 1 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 KEY67793.1 - 2.7e-44 146.8 21.3 0.00038 20.1 0.0 12.0 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.1 KEY67793.1 - 6.2e-37 124.7 19.8 8.4e-06 25.8 0.2 10.6 5 4 5 10 10 10 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEY67793.1 - 8.5e-35 118.5 11.5 6.2e-08 32.9 0.1 9.7 6 3 4 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY67793.1 - 1.1e-30 102.6 6.3 0.021 15.0 0.0 11.2 11 0 0 11 11 11 7 Ankyrin repeat NACHT PF05729.7 KEY67793.1 - 0.0028 17.3 0.0 0.044 13.4 0.0 2.3 2 0 0 2 2 2 1 NACHT domain Sulfate_transp PF00916.15 KEY67794.1 - 1.9e-53 181.3 2.9 1.9e-53 181.3 2.0 1.8 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KEY67794.1 - 9.9e-28 95.6 5.6 9.9e-28 95.6 3.9 2.5 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KEY67794.1 - 1.1e-17 63.5 0.0 2.1e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KEY67794.1 - 0.00025 21.0 0.0 0.00084 19.3 0.0 1.9 1 1 0 1 1 1 1 STAS domain DUF1049 PF06305.6 KEY67794.1 - 1.5 8.3 4.6 19 4.7 0.7 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Thiolase_N PF00108.18 KEY67795.1 - 5.3e-69 232.1 0.1 8.2e-69 231.5 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KEY67795.1 - 1.3e-41 140.8 0.1 3e-41 139.6 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KEY67795.1 - 0.025 14.0 1.5 0.055 12.9 1.0 1.5 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Glyco_hydro_cc PF11790.3 KEY67796.1 - 3e-64 216.7 0.0 3.5e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core E1-E2_ATPase PF00122.15 KEY67798.1 - 1e-62 211.2 5.4 1.1e-62 211.0 2.9 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEY67798.1 - 9.8e-35 119.7 5.2 9.8e-35 119.7 3.6 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEY67798.1 - 2.2e-26 93.6 0.2 3.1e-21 76.7 0.1 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEY67798.1 - 4e-21 74.7 0.0 1.4e-20 73.0 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KEY67798.1 - 1.4e-15 56.4 0.1 5.4e-15 54.6 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KEY67798.1 - 2.2e-12 47.5 0.0 5.6e-12 46.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEY67798.1 - 1.4e-06 28.1 3.6 1.2e-05 25.0 0.2 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Pro_CA PF00484.14 KEY67799.1 - 6.6e-49 165.8 0.0 9.6e-49 165.2 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase DUF1996 PF09362.5 KEY67800.1 - 4.9e-67 226.0 0.7 5.7e-67 225.8 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Peptidase_S58 PF03576.9 KEY67801.1 - 6.6e-111 370.6 4.6 7.5e-111 370.4 3.2 1.0 1 0 0 1 1 1 1 Peptidase family S58 Cas1_AcylT PF07779.7 KEY67802.1 - 2.8e-92 309.7 21.8 3.5e-91 306.1 15.1 2.5 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 KEY67802.1 - 4.2e-12 46.4 0.0 6.1e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p RdRP PF05183.7 KEY67806.1 - 2.9e-154 514.9 0.0 3.9e-154 514.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase zf-C2H2 PF00096.21 KEY67807.1 - 0.0011 19.1 0.2 0.0011 19.1 0.1 3.2 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KEY67807.1 - 0.0045 16.8 0.3 0.0045 16.8 0.2 3.0 4 0 0 4 4 4 1 C2H2-type zinc finger Rtf2 PF04641.7 KEY67807.1 - 0.067 12.3 0.6 0.093 11.9 0.4 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C2H2_2 PF12756.2 KEY67807.1 - 0.11 12.5 0.5 0.25 11.4 0.1 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Ipi1_N PF12333.3 KEY67807.1 - 0.19 11.7 0.6 0.35 10.8 0.4 1.5 1 1 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation UPF0547 PF10571.4 KEY67807.1 - 0.21 11.3 0.2 0.21 11.3 0.2 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-C2H2_4 PF13894.1 KEY67807.1 - 0.43 11.0 0.1 0.43 11.0 0.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Catalase PF00199.14 KEY67808.1 - 0.047 12.3 0.1 0.066 11.8 0.1 1.1 1 0 0 1 1 1 0 Catalase Dabb PF07876.7 KEY67809.1 - 2.6e-26 91.9 0.3 3e-26 91.6 0.2 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DLH PF01738.13 KEY67809.1 - 0.083 12.1 0.2 0.096 11.9 0.1 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family FTA2 PF13095.1 KEY67811.1 - 9.8e-41 139.6 0.0 1.4e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.20 KEY67811.1 - 0.017 14.2 0.0 0.17 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain PE-PPE PF08237.6 KEY67812.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Cellulase PF00150.13 KEY67813.1 - 2.4e-12 46.6 0.0 1e-05 24.8 0.0 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) adh_short PF00106.20 KEY67814.1 - 1.5e-15 57.5 0.1 2.3e-15 56.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY67814.1 - 2.1e-06 27.7 0.0 3.2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY67814.1 - 4.1e-06 26.5 0.0 1e-05 25.2 0.0 1.6 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 KEY67814.1 - 0.014 14.8 0.1 0.028 13.8 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KEY67814.1 - 0.019 13.9 0.0 0.05 12.4 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Nup54 PF13874.1 KEY67815.1 - 1.3 8.7 6.5 0.24 11.0 1.8 1.8 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Ceramidase_alk PF04734.8 KEY67817.1 - 5.6e-276 916.7 0.0 6.4e-276 916.6 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase UvrD_C PF13361.1 KEY67818.1 - 1e-77 262.0 0.9 1.5e-77 261.4 0.6 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 KEY67818.1 - 1.5e-65 221.5 0.6 8.4e-64 215.8 0.0 2.8 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 KEY67818.1 - 7e-14 51.8 0.0 1.7e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 KEY67818.1 - 1.1e-13 50.7 0.3 9.4e-13 47.7 0.1 2.6 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 KEY67818.1 - 3.9e-08 33.1 0.2 1.1e-05 25.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 KEY67818.1 - 8.7e-08 31.9 0.2 0.026 14.0 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 KEY67818.1 - 7.2e-05 22.2 0.1 0.0016 17.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 KEY67818.1 - 0.007 15.9 1.8 0.036 13.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain CcmD PF04995.9 KEY67819.1 - 0.0072 16.0 1.1 1.3 8.8 0.1 2.5 2 0 0 2 2 2 2 Heme exporter protein D (CcmD) Ribosomal_S7 PF00177.16 KEY67820.1 - 9e-24 83.7 0.0 1.4e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Usp PF00582.21 KEY67821.1 - 5e-25 88.3 3.8 1.3e-22 80.5 2.6 3.1 1 1 0 1 1 1 1 Universal stress protein family GHMP_kinases_N PF00288.21 KEY67822.1 - 4.8e-20 71.4 0.0 1.6e-19 69.7 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KEY67822.1 - 1.7e-07 31.3 0.0 3.7e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 KEY67822.1 - 0.022 14.0 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Pterin_4a PF01329.14 KEY67822.1 - 0.13 12.0 0.1 0.42 10.4 0.1 1.8 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase PPTA PF01239.17 KEY67823.1 - 7.2e-43 142.2 7.5 6e-08 31.7 0.0 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_7 PF13176.1 KEY67823.1 - 0.059 13.1 3.9 0.31 10.9 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEY67823.1 - 0.07 13.8 3.0 2.1 9.1 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEY67823.1 - 0.15 12.8 2.0 1.4 9.6 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat NTF2 PF02136.15 KEY67824.1 - 0.066 13.5 1.4 0.71 10.2 0.9 2.1 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain tRNA-synt_1g PF09334.6 KEY67825.1 - 2.5e-113 378.7 0.4 3.6e-113 378.1 0.3 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KEY67825.1 - 3.6e-21 74.8 5.1 1.9e-09 36.1 0.0 3.3 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Acetyltransf_3 PF13302.1 KEY67825.1 - 3.4e-14 53.1 0.0 1.5e-13 51.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain tRNA-synt_1e PF01406.14 KEY67825.1 - 2e-09 36.9 0.0 0.00015 21.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Acetyltransf_1 PF00583.19 KEY67825.1 - 0.0002 21.2 0.1 0.0006 19.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KEY67825.1 - 0.0037 16.9 0.1 0.21 11.3 0.0 2.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.1 KEY67825.1 - 0.022 14.6 0.1 0.94 9.3 0.0 3.1 3 1 0 3 3 3 0 Acetyltransferase (GNAT) domain Peptidase_C28 PF05408.6 KEY67825.1 - 0.095 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase GrpB PF04229.9 KEY67826.1 - 2.2e-47 160.8 0.0 2.6e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 GrpB protein Lzipper-MIP1 PF14389.1 KEY67826.1 - 0.11 12.5 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Ribosomal_L34 PF00468.12 KEY67827.1 - 1.6e-11 43.7 10.1 1.6e-11 43.7 7.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L34 Glyco_hydro_3 PF00933.16 KEY67828.1 - 4.1e-90 301.7 0.0 5.7e-90 301.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY67828.1 - 5.7e-52 176.4 0.0 1.4e-50 171.9 0.0 2.6 3 0 0 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEY67828.1 - 6.2e-23 80.5 0.1 1.3e-22 79.5 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.6 KEY67828.1 - 0.00081 19.4 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 CARDB DUF4352 PF11611.3 KEY67828.1 - 0.15 12.2 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4352) Lipase_3 PF01764.20 KEY67829.1 - 2.3e-33 114.7 0.0 3.5e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KEY67829.1 - 0.0012 18.7 0.1 0.0021 17.9 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KEY67829.1 - 0.0019 17.9 0.6 0.009 15.7 0.4 2.0 1 1 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 KEY67829.1 - 0.0022 17.7 2.5 0.0056 16.4 1.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KEY67829.1 - 0.03 13.9 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein LRR_6 PF13516.1 KEY67830.1 - 0.00018 21.2 0.0 0.48 10.6 0.0 6.0 8 0 0 8 8 8 1 Leucine Rich repeat SNF2_N PF00176.18 KEY67831.1 - 5.4e-61 206.0 0.1 8.5e-61 205.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEY67831.1 - 4.5e-13 48.8 0.0 1.2e-12 47.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 KEY67831.1 - 1.4e-06 27.8 10.2 1.4e-06 27.8 7.1 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KEY67831.1 - 3.2e-06 27.1 0.0 8.4e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.1 KEY67831.1 - 0.0007 19.3 11.4 0.0007 19.3 7.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEY67831.1 - 0.0031 17.4 10.8 0.0031 17.4 7.5 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.1 KEY67831.1 - 0.0052 15.5 0.0 0.022 13.5 0.0 2.0 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 zf-Nse PF11789.3 KEY67831.1 - 0.099 12.1 8.7 0.021 14.3 3.0 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 KEY67831.1 - 0.23 11.2 5.2 0.58 9.9 3.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Peptidase_M14 PF00246.19 KEY67832.1 - 6.2e-64 216.2 0.0 8.7e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 KEY67832.1 - 0.023 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Alpha-L-AF_C PF06964.7 KEY67833.1 - 1.5e-25 90.0 0.0 2.2e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Orn_Arg_deC_N PF02784.11 KEY67834.1 - 9.3e-82 273.9 0.0 1.4e-81 273.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KEY67834.1 - 3.3e-28 97.7 0.1 6.2e-28 96.8 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 KEY67834.1 - 0.0072 15.6 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel M16C_assoc PF08367.6 KEY67835.1 - 4.5e-60 202.5 0.0 7.5e-60 201.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 KEY67835.1 - 3.3e-34 118.1 0.0 1.5e-18 67.1 0.0 3.5 5 0 0 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KEY67835.1 - 2.3e-08 33.9 0.1 2.7e-07 30.4 0.0 2.8 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Taxilin PF09728.4 KEY67836.1 - 6.6e-83 278.3 57.9 6.6e-83 278.3 40.1 1.3 2 0 0 2 2 2 1 Myosin-like coiled-coil protein TMF_TATA_bd PF12325.3 KEY67836.1 - 2 8.1 56.7 0.089 12.5 10.7 5.1 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding Peptidase_M48 PF01435.13 KEY67837.1 - 1.2e-53 182.0 0.2 1.8e-53 181.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 KEY67837.1 - 1.2e-05 24.4 0.0 2.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF955 PF06114.8 KEY67837.1 - 0.1 12.3 0.1 0.27 10.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF955) Peptidase_M57 PF12388.3 KEY67837.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF4538 PF15061.1 KEY67837.1 - 1.2 8.4 3.0 0.8 9.0 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Peptidase_M16_C PF05193.16 KEY67838.1 - 4e-18 65.7 0.0 2.9e-12 46.6 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KEY67838.1 - 3.9e-09 36.4 0.1 1.8e-07 31.0 0.0 2.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) RQC PF09382.5 KEY67838.1 - 0.18 11.5 0.0 0.72 9.6 0.0 1.9 2 0 0 2 2 2 0 RQC domain Zw10 PF06248.8 KEY67839.1 - 6.5e-15 54.3 9.8 5e-12 44.7 4.2 2.5 2 1 0 2 2 2 2 Centromere/kinetochore Zw10 Enolase_N PF03952.11 KEY67839.1 - 0.051 13.4 0.1 0.21 11.5 0.1 2.0 1 0 0 1 1 1 0 Enolase, N-terminal domain Nop14 PF04147.7 KEY67839.1 - 3 5.6 9.6 5.4 4.7 6.7 1.3 1 0 0 1 1 1 0 Nop14-like family PI-PLC-X PF00388.14 KEY67841.1 - 2.4e-59 198.9 0.0 4.3e-59 198.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KEY67841.1 - 2.2e-39 134.0 0.0 5.7e-39 132.7 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 KEY67841.1 - 2.4e-07 30.5 0.1 6.4e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.6 KEY67841.1 - 0.00041 20.3 0.0 0.0012 18.7 0.0 1.9 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_8 PF13833.1 KEY67841.1 - 0.12 12.0 0.0 0.76 9.4 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair zf-DHHC PF01529.15 KEY67842.1 - 3.5e-42 143.7 2.7 5.5e-42 143.1 1.9 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase PMD PF10536.4 KEY67842.1 - 0.11 11.4 1.0 0.13 11.2 0.0 1.5 2 0 0 2 2 2 0 Plant mobile domain Yip1 PF04893.12 KEY67842.1 - 0.19 11.2 8.3 0.097 12.1 1.7 2.1 2 0 0 2 2 2 0 Yip1 domain zf-C2H2 PF00096.21 KEY67843.1 - 1.4e-06 28.2 9.7 0.0083 16.4 0.0 5.2 5 0 0 5 5 5 1 Zinc finger, C2H2 type zf-met PF12874.2 KEY67843.1 - 2e-05 24.6 1.8 0.058 13.6 0.0 3.6 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KEY67843.1 - 7e-05 22.8 1.6 0.046 13.8 0.1 3.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KEY67843.1 - 0.029 14.4 7.8 0.66 10.1 0.0 4.2 2 2 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KEY67843.1 - 0.045 14.1 17.2 0.82 10.1 0.0 5.0 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KEY67843.1 - 0.59 10.1 7.8 2.6 8.0 0.0 4.1 5 0 0 5 5 5 0 C2H2-type zinc finger zf-Di19 PF05605.7 KEY67843.1 - 1.2 9.3 8.9 2.9 8.1 0.0 3.2 2 2 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.2 KEY67843.1 - 1.3 8.8 9.3 1.4 8.7 1.2 2.9 2 1 0 2 2 2 0 Double zinc ribbon zf-C3HC4_3 PF13920.1 KEY67843.1 - 5 6.8 7.1 34 4.2 0.1 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Tau95 PF09734.4 KEY67844.1 - 3.3e-61 207.3 0.0 4.3e-61 206.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit B56 PF01603.15 KEY67845.1 - 2.7e-174 579.5 3.6 3.2e-174 579.3 2.5 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.2 KEY67845.1 - 0.01 15.2 1.3 1.1 8.6 0.2 2.6 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal CTD_bind PF04818.8 KEY67846.1 - 1.1e-09 38.3 0.2 2.1e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. MAS20 PF02064.10 KEY67847.1 - 0.072 12.9 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 MAS20 protein import receptor DUF3824 PF12868.2 KEY67847.1 - 0.09 13.7 3.9 0.31 11.9 2.6 1.7 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) APC_CDC26 PF10471.4 KEY67847.1 - 0.099 13.3 2.4 0.13 12.9 1.7 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Exo_endo_phos PF03372.18 KEY67848.1 - 8.4e-26 91.4 0.4 1.5e-25 90.5 0.3 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CRAL_TRIO PF00650.15 KEY67849.1 - 1.7e-35 121.8 0.0 2.4e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KEY67849.1 - 2.7e-09 37.0 0.1 6.4e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KEY67849.1 - 0.029 14.2 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Apc13p PF05839.6 KEY67850.1 - 5.8e-27 93.5 0.0 6.4e-27 93.3 0.0 1.0 1 0 0 1 1 1 1 Apc13p protein TRAPP PF04051.11 KEY67851.1 - 1.6e-39 134.8 0.0 1.9e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component BCS1_N PF08740.6 KEY67852.1 - 1.8e-38 132.0 1.4 1.8e-38 132.0 1.0 1.9 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 KEY67852.1 - 3.2e-17 62.9 0.0 1.7e-08 34.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEY67852.1 - 0.00031 21.5 0.6 0.00087 20.1 0.1 2.1 2 1 0 2 2 2 1 AAA domain TFIIF_alpha PF05793.7 KEY67852.1 - 0.0071 14.7 12.4 0.011 14.1 8.6 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AAA_25 PF13481.1 KEY67852.1 - 0.0092 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEY67852.1 - 0.02 14.7 0.0 0.054 13.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KEY67852.1 - 0.022 13.8 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus KaiC PF06745.8 KEY67852.1 - 0.075 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF2201_N PF13203.1 KEY67852.1 - 0.077 12.1 9.1 0.03 13.4 4.2 1.8 2 0 0 2 2 2 0 Putative metallopeptidase domain AAA_11 PF13086.1 KEY67852.1 - 0.2 11.2 2.1 1.2 8.6 1.5 2.1 1 1 0 1 1 1 0 AAA domain FLO_LFY PF01698.11 KEY67852.1 - 0.27 10.0 7.8 0.53 9.0 5.4 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein Nucleo_P87 PF07267.6 KEY67852.1 - 5.6 5.5 9.7 9.5 4.7 6.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TIP120 PF08623.5 KEY67853.1 - 9e-63 210.8 9.1 8.7e-61 204.3 0.0 4.8 3 1 2 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 KEY67853.1 - 2.5e-20 72.5 29.4 0.0036 17.5 0.1 10.1 7 3 6 13 13 13 9 HEAT repeats HEAT PF02985.17 KEY67853.1 - 2e-12 46.0 21.0 1.4 9.1 0.1 12.6 14 0 0 14 14 14 4 HEAT repeat HEAT_EZ PF13513.1 KEY67853.1 - 1.8e-06 28.2 33.3 0.16 12.5 0.5 13.4 10 3 6 16 16 16 2 HEAT-like repeat Cnd1 PF12717.2 KEY67853.1 - 2.1e-06 27.7 10.5 1.3 8.8 0.0 7.4 6 2 2 8 8 8 3 non-SMC mitotic condensation complex subunit 1 VHS PF00790.14 KEY67853.1 - 0.0062 16.1 0.0 5.8 6.5 0.0 3.4 2 0 0 2 2 2 2 VHS domain Ipi1_N PF12333.3 KEY67853.1 - 0.017 15.0 0.0 13 5.7 0.0 5.0 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation Proteasom_PSMB PF10508.4 KEY67853.1 - 0.03 12.6 6.4 0.094 10.9 0.3 3.7 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit DUF3361 PF11841.3 KEY67853.1 - 8.4 6.0 8.9 38 3.9 0.0 4.3 4 1 0 5 5 5 0 Domain of unknown function (DUF3361) Pec_lyase_C PF00544.14 KEY67854.1 - 2.1e-40 138.3 6.5 4e-39 134.1 4.5 2.1 1 1 0 1 1 1 1 Pectate lyase E1-E2_ATPase PF00122.15 KEY67855.1 - 7.1e-18 64.4 0.2 3.5e-17 62.2 0.0 2.1 2 1 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 KEY67855.1 - 1.1e-13 51.8 0.0 5.4e-13 49.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEY67855.1 - 1.2e-13 51.9 0.0 2.3e-12 47.7 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEY67855.1 - 1e-12 47.8 0.0 2.4e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEY67855.1 - 0.00071 19.2 0.0 0.0019 17.7 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Homeobox PF00046.24 KEY67856.1 - 3.9e-20 71.2 2.7 8.1e-20 70.1 1.9 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KEY67856.1 - 0.0025 17.4 0.3 0.0073 15.9 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain CAF-1_p150 PF11600.3 KEY67856.1 - 0.46 9.8 6.2 0.65 9.3 4.3 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Adaptin_binding PF10199.4 KEY67858.1 - 9.3e-15 55.1 1.6 2.2e-14 53.8 1.1 1.6 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 NdhL PF10716.4 KEY67859.1 - 0.01 15.5 2.9 0.019 14.7 2.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit F-box PF00646.28 KEY67860.1 - 0.00027 20.5 0.3 0.00064 19.3 0.2 1.6 1 0 0 1 1 1 1 F-box domain ABC_tran PF00005.22 KEY67861.1 - 1e-51 174.8 0.0 1.2e-30 106.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEY67861.1 - 1.7e-45 155.6 24.3 5.3e-27 94.9 4.5 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 KEY67861.1 - 9.2e-10 38.1 0.1 0.0056 15.9 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KEY67861.1 - 7.5e-09 36.1 0.0 0.00018 21.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 KEY67861.1 - 5.4e-07 29.8 0.0 0.97 9.3 0.0 3.9 4 0 0 4 4 4 2 AAA domain T2SE PF00437.15 KEY67861.1 - 8.3e-06 24.8 0.0 0.0073 15.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 KEY67861.1 - 1.9e-05 24.7 0.0 0.051 13.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.7 KEY67861.1 - 3.4e-05 23.0 1.0 0.11 11.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 KEY67861.1 - 5.3e-05 22.7 0.0 0.11 11.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KEY67861.1 - 6.7e-05 22.3 0.6 0.43 10.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KEY67861.1 - 0.00021 20.5 0.1 0.52 9.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KEY67861.1 - 0.00074 20.3 0.0 2.7 8.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KEY67861.1 - 0.001 18.5 0.0 0.19 11.1 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein MMR_HSR1 PF01926.18 KEY67861.1 - 0.0011 18.8 0.1 0.11 12.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 KEY67861.1 - 0.0014 18.1 0.2 0.63 9.4 0.0 3.3 4 0 0 4 4 3 1 AAA-like domain AAA_22 PF13401.1 KEY67861.1 - 0.0014 18.7 0.2 7.3 6.7 0.0 3.5 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 KEY67861.1 - 0.0034 17.8 0.1 4.7 7.7 0.1 2.9 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 KEY67861.1 - 0.005 16.3 0.1 0.74 9.2 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family ResIII PF04851.10 KEY67861.1 - 0.0069 16.2 0.0 3.1 7.5 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA PF00004.24 KEY67861.1 - 0.0077 16.4 0.1 8.5 6.5 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 KEY67861.1 - 0.0086 15.9 2.7 0.098 12.4 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function DUF87 MobB PF03205.9 KEY67861.1 - 0.0096 15.6 0.2 13 5.4 0.1 3.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KEY67861.1 - 0.01 16.1 0.0 4.2 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KEY67861.1 - 0.016 14.7 1.1 5.4 6.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain TIP49 PF06068.8 KEY67861.1 - 0.019 13.7 0.7 0.96 8.0 0.1 2.2 2 0 0 2 2 2 0 TIP49 C-terminus DEAD PF00270.24 KEY67861.1 - 0.11 12.0 0.0 7.2 6.0 0.0 2.9 2 1 1 3 3 3 0 DEAD/DEAH box helicase RNA_helicase PF00910.17 KEY67861.1 - 0.13 12.4 0.0 33 4.7 0.0 2.8 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 KEY67861.1 - 0.14 11.8 0.5 12 5.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 KEY67861.1 - 0.17 11.3 1.6 0.6 9.5 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain TrwB_AAD_bind PF10412.4 KEY67861.1 - 0.19 10.3 1.9 7.6 5.0 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.1 KEY67861.1 - 5.9 6.7 7.1 6.4 6.6 0.1 3.5 3 1 0 3 3 3 0 Part of AAA domain SecY PF00344.15 KEY67862.1 - 4.5e-96 321.8 9.3 5.8e-96 321.4 6.4 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KEY67862.1 - 1.1e-16 59.9 0.1 5.3e-16 57.8 0.2 2.2 2 0 0 2 2 2 1 Plug domain of Sec61p IPPT PF01715.12 KEY67863.1 - 7.4e-54 182.4 0.2 1.1e-53 181.8 0.2 1.2 1 0 0 1 1 1 1 IPP transferase AAA_17 PF13207.1 KEY67863.1 - 1.5e-05 25.8 0.4 9.3e-05 23.2 0.2 2.4 1 1 0 1 1 1 1 AAA domain IPT PF01745.11 KEY67863.1 - 0.00014 21.1 0.1 0.0022 17.2 0.0 2.1 2 0 0 2 2 2 1 Isopentenyl transferase AAA_33 PF13671.1 KEY67863.1 - 0.001 18.9 0.1 0.2 11.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEY67863.1 - 0.0026 18.0 0.1 0.012 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEY67863.1 - 0.045 13.8 0.0 0.2 11.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KEY67863.1 - 0.056 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 KEY67863.1 - 0.079 12.6 0.0 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) zf-C2H2_jaz PF12171.3 KEY67863.1 - 0.081 13.0 0.2 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Hpr_kinase_C PF07475.7 KEY67863.1 - 0.098 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA PF00004.24 KEY67863.1 - 0.1 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-C2H2_2 PF12756.2 KEY67863.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) RNA_helicase PF00910.17 KEY67863.1 - 0.18 11.9 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Fungal_trans PF04082.13 KEY67864.1 - 4.4e-18 65.1 0.1 6.8e-18 64.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sdh_cyt PF01127.17 KEY67864.1 - 6e-14 51.9 3.7 1.2e-13 50.9 2.6 1.5 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Zn_clus PF00172.13 KEY67864.1 - 1e-08 34.9 9.4 1.6e-08 34.2 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1546 PF07571.8 KEY67865.1 - 3.4e-27 94.3 0.0 6.3e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 KEY67865.1 - 4e-22 77.9 0.2 6.8e-22 77.1 0.2 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 KEY67865.1 - 1.1e-05 25.4 0.1 2.1e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KEY67865.1 - 0.078 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DJ-1_PfpI PF01965.19 KEY67866.1 - 1.5e-24 86.1 0.1 2.3e-24 85.5 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KEY67866.1 - 2.5e-13 49.2 0.1 5e-13 48.3 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family GATase_3 PF07685.9 KEY67866.1 - 0.086 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain ADH_N PF08240.7 KEY67867.1 - 7.2e-24 83.6 5.9 1.2e-23 82.9 4.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY67867.1 - 1e-18 67.0 0.0 2.5e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KEY67867.1 - 4.4e-05 22.7 0.0 7.2e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 KEY67867.1 - 0.00024 21.9 0.0 0.00051 20.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KEY67867.1 - 0.0065 16.0 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.16 KEY67867.1 - 0.49 10.2 1.9 1.2 8.9 1.3 1.6 1 0 0 1 1 1 0 ThiF family Opi1 PF08618.5 KEY67868.1 - 4.8e-62 210.2 2.1 1.1e-51 176.0 0.1 2.9 1 1 1 2 2 2 2 Transcription factor Opi1 Mur_ligase_M PF08245.7 KEY67869.1 - 2.7e-05 24.2 0.0 5.4e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 KEY67869.1 - 0.022 14.8 0.0 0.051 13.6 0.0 1.7 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Adap_comp_sub PF00928.16 KEY67870.1 - 3.4e-89 298.4 0.0 4.5e-89 298.0 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KEY67870.1 - 2.1e-08 33.9 0.2 3.5e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SET PF00856.23 KEY67872.1 - 2.1e-13 50.8 0.0 1.5e-12 48.0 0.0 2.1 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 KEY67872.1 - 1.7e-05 24.7 0.0 3.9e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding UvdE PF03851.9 KEY67873.1 - 2.5e-113 377.6 0.0 3.5e-113 377.2 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE AMMECR1 PF01871.12 KEY67875.1 - 7.1e-45 152.1 0.0 1.6e-44 151.0 0.0 1.5 2 0 0 2 2 2 1 AMMECR1 Ras PF00071.17 KEY67876.1 - 2e-39 134.6 0.0 2.4e-25 88.8 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KEY67876.1 - 8.3e-12 45.6 0.0 1.6e-11 44.7 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KEY67876.1 - 0.0021 17.3 0.0 0.019 14.2 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KEY67876.1 - 0.0064 16.4 0.0 0.0096 15.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEY67876.1 - 0.019 14.3 0.1 0.8 9.1 0.0 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PRK PF00485.13 KEY67876.1 - 0.049 13.1 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Pyridoxal_deC PF00282.14 KEY67877.1 - 1.7e-76 257.0 0.0 7e-75 251.7 0.0 2.0 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KEY67877.1 - 1.6e-05 24.1 0.0 2.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KEY67877.1 - 0.00077 18.2 0.0 0.0017 17.1 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Penicillinase_R PF03965.11 KEY67877.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Penicillinase repressor GlyL_C PF12524.3 KEY67878.1 - 0.051 13.5 0.7 0.082 12.8 0.2 1.7 1 1 1 2 2 2 0 dsDNA virus glycoprotein L C terminal PUF PF00806.14 KEY67879.1 - 1.4e-12 46.3 0.0 0.22 11.0 0.0 6.2 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat P4Ha_N PF08336.6 KEY67880.1 - 0.084 12.6 0.2 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region CobU PF02283.11 KEY67880.1 - 0.24 10.8 1.1 0.37 10.1 0.8 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Oxysterol_BP PF01237.13 KEY67881.1 - 3.6e-54 183.6 0.0 7e-43 146.4 0.0 2.3 2 1 0 2 2 2 2 Oxysterol-binding protein Glyco_hydro_7 PF00840.15 KEY67882.1 - 3.2e-198 658.4 16.2 4.2e-198 658.0 11.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 KEY67882.1 - 4.8e-10 38.9 15.6 4.8e-10 38.9 10.8 5.0 4 1 1 5 5 5 1 Fungal cellulose binding domain MAM33 PF02330.11 KEY67883.1 - 9.4e-30 103.9 4.5 7.7e-28 97.6 3.1 2.0 1 1 0 1 1 1 1 Mitochondrial glycoprotein DUF2962 PF11176.3 KEY67884.1 - 5.1e-40 136.5 1.2 5.8e-40 136.3 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) DUF1347 PF07079.6 KEY67884.1 - 0.1 10.7 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1347) XPG_I PF00867.13 KEY67885.1 - 1.3e-25 89.2 0.0 2.6e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KEY67885.1 - 4.5e-08 33.2 0.0 9.2e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 KEY67885.1 - 0.00031 20.3 0.0 0.00059 19.4 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing TPR_11 PF13414.1 KEY67885.1 - 0.0055 16.3 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 TPR repeat DNA_pol_lambd_f PF10391.4 KEY67885.1 - 0.2 11.2 0.0 39 3.8 0.0 3.1 3 0 0 3 3 3 0 Fingers domain of DNA polymerase lambda IBR PF01485.16 KEY67886.1 - 5.3e-22 77.4 40.9 1.5e-11 44.0 3.0 4.5 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 KEY67886.1 - 4.2e-05 23.4 7.4 4.2e-05 23.4 5.1 4.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEY67886.1 - 0.00013 21.7 5.4 0.00013 21.7 3.7 3.7 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 KEY67886.1 - 0.00022 20.8 5.9 0.00022 20.8 4.1 4.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) UN_NPL4 PF11543.3 KEY67886.1 - 0.021 15.0 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Redoxin PF08534.5 KEY67887.1 - 4.2e-27 94.4 0.0 5e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KEY67887.1 - 4.9e-06 26.2 0.0 6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Na_Ca_ex PF01699.19 KEY67888.1 - 5.5e-28 97.3 15.9 4.6e-17 61.9 2.7 2.8 2 1 0 2 2 2 2 Sodium/calcium exchanger protein DUF3169 PF11368.3 KEY67888.1 - 0.014 14.5 0.3 0.014 14.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF202 PF02656.10 KEY67888.1 - 5.4 7.3 13.4 3.2 8.0 0.4 4.2 3 2 0 3 3 3 0 Domain of unknown function (DUF202) DUF4131 PF13567.1 KEY67888.1 - 7.4 5.9 9.8 8.1 5.8 0.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) RasGAP PF00616.14 KEY67889.1 - 4.3e-54 183.1 0.0 3.8e-53 180.0 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 KEY67889.1 - 8.9e-31 106.4 6.3 1.2e-30 106.0 2.7 2.4 2 0 0 2 2 2 1 RasGAP C-terminus MeMO_Hyd_G PF02964.11 KEY67889.1 - 0.032 14.1 0.1 0.079 12.8 0.1 1.6 1 0 0 1 1 1 0 Methane monooxygenase, hydrolase gamma chain DUF972 PF06156.8 KEY67889.1 - 0.78 10.1 5.4 12 6.2 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) CorA PF01544.13 KEY67890.1 - 1e-13 50.9 0.1 2.2e-13 49.9 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DivIVA PF05103.8 KEY67890.1 - 0.0094 15.9 0.3 1.5 8.8 0.1 3.0 3 0 0 3 3 3 1 DivIVA protein CCDC155 PF14662.1 KEY67890.1 - 0.048 13.2 0.2 0.092 12.3 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Hrs_helical PF12210.3 KEY67890.1 - 0.081 13.1 0.2 4.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate ASF1_hist_chap PF04729.8 KEY67891.1 - 3.5e-66 221.5 0.1 4.8e-66 221.1 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone DUF966 PF06136.8 KEY67891.1 - 0.2 11.0 3.3 0.24 10.7 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Suf PF05843.9 KEY67892.1 - 3.5e-75 253.3 0.0 3.3e-73 246.8 0.0 3.0 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KEY67892.1 - 0.0038 17.7 0.1 0.14 12.9 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat HAT PF02184.11 KEY67892.1 - 0.073 12.8 0.3 0.3 10.8 0.2 2.0 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat HrpJ PF07201.6 KEY67892.1 - 0.23 11.4 2.1 20 5.1 0.0 3.6 4 0 0 4 4 4 0 HrpJ-like domain Piwi PF02171.12 KEY67893.1 - 1.8e-74 250.4 0.0 2.6e-74 249.9 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KEY67893.1 - 2.4e-13 49.5 0.0 5.7e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KEY67893.1 - 3.7e-10 39.0 0.0 1e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Lgl_C PF08596.5 KEY67894.1 - 3.6e-118 394.4 0.0 5.9e-118 393.7 0.0 1.3 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 KEY67894.1 - 8e-07 28.7 0.0 0.013 15.4 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 KEY67894.1 - 0.33 9.0 0.0 7.1 4.6 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Pyridoxal_deC PF00282.14 KEY67895.1 - 1.5e-64 217.7 0.0 1.9e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KEY67895.1 - 7.2e-10 38.4 0.0 1e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KEY67895.1 - 3.4e-09 36.1 0.0 5.5e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KEY67895.1 - 1.8e-08 33.5 0.0 2.5e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V SLA_LP_auto_ag PF05889.8 KEY67895.1 - 0.00066 18.2 0.0 0.0014 17.1 0.0 1.5 2 0 0 2 2 2 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) DUF868 PF05910.7 KEY67895.1 - 0.013 14.9 0.2 0.026 14.0 0.1 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF868) SHMT PF00464.14 KEY67896.1 - 1.3e-208 692.2 0.0 1.5e-208 691.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 KEY67896.1 - 7.3e-06 24.9 0.1 1.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KEY67896.1 - 0.00012 21.1 0.0 0.00025 20.0 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KEY67896.1 - 0.0022 17.2 0.0 0.004 16.3 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Baculo_DNA_bind PF04786.7 KEY67896.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 ssDNA binding protein RINT1_TIP1 PF04437.8 KEY67897.1 - 8.9e-92 308.1 0.0 1.3e-91 307.6 0.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Bcl-2_BAD PF10514.4 KEY67897.1 - 0.037 13.9 0.3 0.1 12.5 0.2 1.7 1 0 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD LcrG PF07216.7 KEY67897.1 - 0.43 10.6 3.9 4.7 7.3 0.0 3.1 3 0 0 3 3 3 0 LcrG protein DUF4164 PF13747.1 KEY67897.1 - 0.54 10.4 8.8 0.96 9.6 4.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Band_7 PF01145.20 KEY67897.1 - 3.9 7.3 6.2 1.5 8.7 2.0 1.9 2 0 0 2 2 2 0 SPFH domain / Band 7 family Mito_carr PF00153.22 KEY67898.1 - 4.2e-62 205.8 2.2 6.1e-21 73.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sec34 PF04136.10 KEY67899.1 - 1.6e-30 105.8 0.3 5.2e-30 104.2 0.2 1.9 1 0 0 1 1 1 1 Sec34-like family RCC1 PF00415.13 KEY67900.1 - 1.5e-27 95.5 9.5 9.3e-05 22.5 0.0 8.5 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEY67900.1 - 1.3e-09 37.4 0.7 4.5e-07 29.3 0.0 7.3 7 2 0 7 7 7 2 Regulator of chromosome condensation (RCC1) repeat Y_phosphatase PF00102.22 KEY67901.1 - 1.2e-47 162.2 0.0 1.9e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KEY67901.1 - 0.00025 21.1 0.0 0.0013 18.8 0.0 2.0 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.15 KEY67901.1 - 0.00069 19.2 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KEY67901.1 - 0.012 15.9 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family GKAP PF03359.8 KEY67901.1 - 0.18 11.4 0.7 0.34 10.4 0.5 1.3 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein Miff PF05644.6 KEY67902.1 - 0.15 11.6 0.5 0.32 10.5 0.3 1.5 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Prefoldin PF02996.12 KEY67904.1 - 6.1e-36 122.6 0.0 9.2e-36 122.1 0.0 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 KEY67904.1 - 0.00022 20.9 0.1 0.0052 16.5 0.0 2.3 1 1 0 2 2 2 1 Prefoldin subunit Filament PF00038.16 KEY67904.1 - 0.0011 18.4 0.5 0.074 12.5 0.0 2.0 2 0 0 2 2 2 2 Intermediate filament protein DUF4201 PF13870.1 KEY67904.1 - 0.054 12.9 0.8 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) HR1 PF02185.11 KEY67904.1 - 0.058 13.1 0.0 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Hr1 repeat Syntaxin-6_N PF09177.6 KEY67904.1 - 0.11 12.9 0.4 7.2 7.0 0.1 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal FlaC_arch PF05377.6 KEY67904.1 - 0.12 12.3 0.5 9.9 6.1 0.0 2.7 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) VanZ PF04892.7 KEY67905.1 - 7.8e-13 48.5 2.6 1.2e-12 47.9 1.8 1.3 1 1 0 1 1 1 1 VanZ like family DUF4401 PF14351.1 KEY67905.1 - 0.0017 17.3 1.2 0.0024 16.9 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) Polysacc_synt PF01943.12 KEY67905.1 - 0.024 13.8 1.4 0.029 13.6 1.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkH PF02386.11 KEY67905.1 - 0.091 11.3 2.6 0.11 10.9 1.8 1.1 1 0 0 1 1 1 0 Cation transport protein YfhO PF09586.5 KEY67905.1 - 0.41 8.5 2.8 0.49 8.3 1.9 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO UPF0118 PF01594.11 KEY67905.1 - 0.94 8.3 6.7 1.4 7.8 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF20 DUF3094 PF11293.3 KEY67905.1 - 2.6 7.5 4.6 1.4 8.4 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) Bromodomain PF00439.20 KEY67906.1 - 5.1e-20 71.1 1.8 3.2e-19 68.6 0.3 2.5 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.8 KEY67906.1 - 1.6e-09 37.3 0.0 3.7e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated Ferric_reduct PF01794.14 KEY67907.1 - 4.5e-14 52.6 12.4 4.5e-14 52.6 8.6 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KEY67907.1 - 2.2e-12 47.1 0.0 3.4e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KEY67907.1 - 5.3e-06 26.2 0.0 3.8e-05 23.5 0.0 2.3 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KEY67907.1 - 0.00017 22.0 0.0 0.9 10.1 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain RRM_1 PF00076.17 KEY67908.1 - 9.1e-08 31.6 0.0 1.8e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY67908.1 - 3.5e-06 26.9 0.0 1e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY67908.1 - 0.00016 21.4 0.0 0.00028 20.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1387 PF07139.6 KEY67908.1 - 0.13 11.8 3.5 0.22 11.0 2.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1387) RF-1 PF00472.15 KEY67909.1 - 2.9e-12 46.3 4.2 5.7e-12 45.4 2.9 1.5 1 1 0 1 1 1 1 RF-1 domain DUF4367 PF14285.1 KEY67909.1 - 0.17 11.1 0.8 0.27 10.5 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) Pkinase PF00069.20 KEY67910.1 - 4.8e-67 225.8 0.0 6.2e-67 225.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY67910.1 - 1.1e-28 100.0 0.0 1.4e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY67910.1 - 6.9e-07 28.5 0.0 1e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEY67910.1 - 0.00019 21.2 0.0 0.00028 20.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KEY67910.1 - 0.0019 17.3 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KEY67910.1 - 0.03 13.6 0.0 0.077 12.3 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PAP2 PF01569.16 KEY67911.1 - 5.5e-14 51.9 6.0 5.5e-14 51.9 4.2 2.3 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 KEY67911.1 - 9e-08 31.8 6.2 2.4e-07 30.4 4.3 1.6 1 1 0 1 1 1 1 PAP2 superfamily RNA_polI_A34 PF08208.6 KEY67912.1 - 1.7e-17 63.7 38.5 1.7e-17 63.7 26.7 6.0 2 2 1 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 Clp1 PF06807.9 KEY67913.1 - 5e-14 52.5 0.0 1.8e-13 50.7 0.0 1.8 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 AAA_17 PF13207.1 KEY67913.1 - 0.0002 22.1 0.0 0.00068 20.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 KEY67913.1 - 0.00069 19.3 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KEY67913.1 - 0.018 14.5 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 KEY67913.1 - 0.029 14.2 0.2 0.12 12.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain NIF3 PF01784.13 KEY67915.1 - 8.7e-56 189.1 0.0 1e-55 188.9 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) LptC PF06835.8 KEY67915.1 - 0.029 13.7 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide-assembly, LptC-related Vps51 PF08700.6 KEY67916.1 - 1.7e-28 98.2 0.1 2.9e-28 97.5 0.1 1.4 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.7 KEY67916.1 - 1.2e-05 23.9 0.1 1.5e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.4 KEY67916.1 - 0.00088 19.2 0.4 0.0032 17.4 0.3 1.8 1 1 0 1 1 1 1 Golgi transport complex subunit 5 RepB-RCR_reg PF10723.4 KEY67916.1 - 0.072 12.8 0.2 0.16 11.6 0.1 1.6 1 0 0 1 1 1 0 Replication regulatory protein RepB DUF1767 PF08585.7 KEY67917.1 - 9.8e-06 25.7 0.1 2.1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Gly_reductase PF09338.6 KEY67917.1 - 0.019 13.1 0.2 0.029 12.5 0.1 1.3 1 1 0 1 1 1 0 Glycine/sarcosine/betaine reductase component B subunits TPR_11 PF13414.1 KEY67918.1 - 7.3e-52 172.9 30.5 4.1e-07 29.5 0.1 13.5 8 4 8 16 16 16 13 TPR repeat TPR_16 PF13432.1 KEY67918.1 - 8.3e-48 160.1 36.0 9.2e-09 35.7 0.6 14.4 12 3 4 16 16 16 10 Tetratricopeptide repeat TPR_2 PF07719.12 KEY67918.1 - 2e-43 142.8 38.0 0.0017 18.1 0.0 17.5 16 0 0 16 16 16 10 Tetratricopeptide repeat TPR_14 PF13428.1 KEY67918.1 - 2.4e-40 133.3 28.9 4.9e-05 23.6 0.0 16.4 11 5 6 17 17 16 9 Tetratricopeptide repeat TPR_1 PF00515.23 KEY67918.1 - 9.8e-35 116.7 37.0 0.00024 20.5 0.0 16.4 18 0 0 18 18 18 9 Tetratricopeptide repeat TPR_17 PF13431.1 KEY67918.1 - 4e-33 110.8 5.8 0.057 13.6 0.0 17.6 18 0 0 18 18 17 5 Tetratricopeptide repeat TPR_19 PF14559.1 KEY67918.1 - 9.3e-32 109.1 22.9 4.9e-05 23.5 0.0 10.6 8 3 5 13 13 12 9 Tetratricopeptide repeat TPR_12 PF13424.1 KEY67918.1 - 1e-22 79.8 34.7 3.1e-06 27.0 0.1 13.2 8 3 6 15 15 15 8 Tetratricopeptide repeat TPR_8 PF13181.1 KEY67918.1 - 2.3e-22 77.0 20.8 0.011 15.5 0.0 13.8 15 1 1 16 16 14 4 Tetratricopeptide repeat TPR_7 PF13176.1 KEY67918.1 - 9.5e-22 75.0 23.8 0.0016 18.0 0.0 15.0 16 2 2 18 18 15 5 Tetratricopeptide repeat TPR_6 PF13174.1 KEY67918.1 - 4.4e-15 55.0 26.7 0.00065 19.9 0.0 15.0 19 0 0 19 19 15 1 Tetratricopeptide repeat Apc3 PF12895.2 KEY67918.1 - 3.3e-14 52.7 14.7 8.5e-06 25.8 0.1 8.1 6 2 4 10 10 9 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KEY67918.1 - 2.7e-09 36.7 19.2 0.051 13.4 0.4 8.8 9 2 1 10 10 9 3 Tetratricopeptide repeat TPR_20 PF14561.1 KEY67918.1 - 0.0005 20.1 19.2 1.1 9.4 0.1 7.5 7 1 1 8 8 6 1 Tetratricopeptide repeat HemY_N PF07219.8 KEY67918.1 - 0.0011 18.5 0.3 3.6 7.2 0.0 4.4 3 1 1 4 4 3 1 HemY protein N-terminus TPR_10 PF13374.1 KEY67918.1 - 0.0012 18.6 19.9 1.1 9.3 0.1 8.7 11 0 0 11 11 8 1 Tetratricopeptide repeat ChAPs PF09295.5 KEY67918.1 - 0.0021 16.8 0.5 5.8 5.5 0.0 4.7 5 1 1 6 6 6 1 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.1 KEY67918.1 - 0.015 15.1 10.5 3.6 7.5 0.0 7.5 9 0 0 9 9 9 0 Fis1 C-terminal tetratricopeptide repeat EXS PF03124.9 KEY67918.1 - 0.036 13.1 0.1 0.069 12.1 0.1 1.4 1 0 0 1 1 1 0 EXS family TPR_4 PF07721.9 KEY67918.1 - 4.2 8.0 21.2 3.1 8.4 0.2 8.5 10 0 0 10 10 7 0 Tetratricopeptide repeat Cellulase PF00150.13 KEY67919.1 - 3.6e-12 46.0 2.3 9.8e-09 34.8 0.6 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 KEY67919.1 - 0.0032 16.8 0.1 0.0055 16.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 KEY67919.1 - 0.0042 16.2 0.1 1 8.4 0.0 2.2 2 0 0 2 2 2 2 Beta-galactosidase MamL-1 PF09596.5 KEY67919.1 - 0.04 13.7 0.3 0.083 12.7 0.2 1.4 1 0 0 1 1 1 0 MamL-1 domain Pkinase PF00069.20 KEY67920.1 - 1.6e-64 217.6 0.0 2.3e-64 217.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY67920.1 - 1.9e-47 161.5 0.0 2.9e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY67920.1 - 3.5e-09 36.0 0.0 1.2e-07 31.0 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 KEY67920.1 - 0.0042 16.1 0.0 0.0076 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2201_N PF13203.1 KEY67922.1 - 0.071 12.2 1.3 0.074 12.2 0.9 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Glyco_hydro_47 PF01532.15 KEY67923.1 - 2e-166 554.1 0.0 2.5e-166 553.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 KEY67923.1 - 0.13 10.4 0.0 8.5 4.5 0.0 2.1 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) Adeno_E3_14_5 PF04834.7 KEY67923.1 - 0.79 10.1 4.0 0.62 10.5 0.1 2.5 2 0 0 2 2 2 0 Early E3 14.5 kDa protein DUF1183 PF06682.7 KEY67923.1 - 7.4 6.0 8.0 0.97 8.9 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1183) Fig1 PF12351.3 KEY67924.1 - 9.2e-56 188.6 2.7 9.2e-56 188.6 1.9 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 KEY67924.1 - 7.3e-10 38.7 4.0 1.1e-09 38.1 2.7 1.3 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 KEY67924.1 - 0.00032 19.6 8.1 0.00032 19.6 5.6 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) DUF202 PF02656.10 KEY67924.1 - 0.31 11.2 10.0 0.33 11.2 0.2 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF202) ODV-E18 PF10717.4 KEY67924.1 - 0.85 9.1 9.5 0.93 8.9 0.8 3.2 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 MLTD_N PF06474.7 KEY67924.1 - 6.1 7.1 7.2 1.6 9.0 1.9 2.4 2 0 0 2 2 2 0 MltD lipid attachment motif Thi4 PF01946.12 KEY67925.1 - 2.8e-105 350.5 0.0 3.5e-105 350.1 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KEY67925.1 - 6e-08 31.9 0.6 1.1e-07 31.1 0.4 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY67925.1 - 5.3e-06 26.3 0.3 1.4e-05 24.9 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KEY67925.1 - 1.6e-05 24.0 0.3 3.7e-05 22.8 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEY67925.1 - 0.00014 21.8 0.1 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY67925.1 - 0.00036 20.6 0.1 0.00054 20.0 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEY67925.1 - 0.00056 19.7 1.4 0.00096 18.9 0.1 2.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KEY67925.1 - 0.0024 16.7 2.5 0.0056 15.5 0.6 2.2 2 1 1 3 3 3 1 FAD binding domain FAD_oxidored PF12831.2 KEY67925.1 - 0.0032 16.6 0.0 0.0045 16.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KEY67925.1 - 0.022 13.8 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 KEY67925.1 - 0.029 12.9 0.2 0.043 12.4 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 KEY67925.1 - 0.051 12.0 0.3 0.071 11.5 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Shikimate_DH PF01488.15 KEY67925.1 - 0.089 12.8 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 KEY67925.1 - 0.11 11.3 0.2 0.41 9.4 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A BolA PF01722.13 KEY67926.1 - 7.1e-22 77.1 0.0 9e-22 76.8 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Adaptin_N PF01602.15 KEY67927.1 - 5.4e-146 486.9 3.8 7.7e-146 486.4 2.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KEY67927.1 - 8.1e-27 94.2 1.0 5.3e-26 91.5 0.0 2.6 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KEY67927.1 - 2.5e-18 66.1 0.2 4.2e-07 30.1 0.0 5.0 3 2 2 5 5 5 4 HEAT repeats HEAT PF02985.17 KEY67927.1 - 1.1e-11 43.7 3.3 0.012 15.6 0.0 6.1 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 KEY67927.1 - 5.3e-06 26.7 0.4 2 9.0 0.0 5.7 6 1 1 7 7 7 1 HEAT-like repeat UNC45-central PF11701.3 KEY67927.1 - 0.0013 18.3 0.2 0.71 9.5 0.0 2.8 2 1 0 2 2 2 2 Myosin-binding striated muscle assembly central CLASP_N PF12348.3 KEY67927.1 - 0.012 14.9 0.1 1.5 8.1 0.0 3.4 2 1 1 3 3 3 0 CLASP N terminal Arm PF00514.18 KEY67927.1 - 0.014 15.2 0.7 2.5 8.0 0.0 4.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat TFIID-18kDa PF02269.11 KEY67927.1 - 0.027 14.2 0.6 17 5.3 0.1 3.2 3 0 0 3 3 3 0 Transcription initiation factor IID, 18kD subunit Bcl-2 PF00452.14 KEY67927.1 - 0.074 13.1 0.3 0.42 10.7 0.0 2.4 3 0 0 3 3 3 0 Apoptosis regulator proteins, Bcl-2 family DNA_ligase_A_M PF01068.16 KEY67928.1 - 3.2e-48 163.7 0.1 1e-45 155.6 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KEY67928.1 - 8e-41 139.7 0.1 1.8e-40 138.6 0.0 1.6 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KEY67928.1 - 1.3e-19 70.3 0.1 7.5e-19 67.9 0.0 2.4 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region PCI_Csn8 PF10075.4 KEY67929.1 - 2.2e-32 111.7 0.0 3e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KEY67929.1 - 5.3e-20 71.8 0.0 7.3e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PDCD2_C PF04194.8 KEY67930.1 - 4.9e-53 179.0 0.1 1.6e-52 177.4 0.0 1.7 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain DSBA PF01323.15 KEY67930.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Cpn60_TCP1 PF00118.19 KEY67931.1 - 1.2e-148 495.8 0.2 1.3e-148 495.6 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4470 PF14737.1 KEY67932.1 - 1.5e-22 79.2 0.1 3.4e-22 78.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 KEY67932.1 - 1.7e-11 43.8 17.2 3.8e-11 42.6 11.9 1.7 1 0 0 1 1 1 1 MYND finger zf-C2H2 PF00096.21 KEY67933.1 - 4.1e-10 39.3 19.9 0.00043 20.4 4.8 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KEY67933.1 - 8.6e-09 35.2 12.2 0.00024 21.2 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KEY67933.1 - 0.001 19.2 17.3 0.094 13.0 0.1 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger AT_hook PF02178.14 KEY67933.1 - 1 9.2 5.2 3.9 7.4 3.6 2.0 1 0 0 1 1 1 0 AT hook motif CBS PF00571.23 KEY67934.1 - 2e-39 133.0 12.5 2e-10 40.3 0.0 5.6 6 0 0 6 6 6 4 CBS domain PB1 PF00564.19 KEY67934.1 - 1.6e-08 34.1 0.0 5.2e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 PB1 domain PBP1_TM PF14812.1 KEY67934.1 - 1.7 9.0 10.4 0.036 14.3 2.0 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_S2 PF00318.15 KEY67935.1 - 1.5e-49 168.1 0.0 2.8e-49 167.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S2 Prominin PF05478.6 KEY67935.1 - 0.12 9.8 0.6 0.18 9.2 0.4 1.2 1 0 0 1 1 1 0 Prominin Yae1_N PF09811.4 KEY67935.1 - 0.7 9.4 3.5 0.45 10.0 0.7 2.1 2 0 0 2 2 2 0 Essential protein Yae1, N terminal zf-H2C2 PF09337.5 KEY67936.1 - 8.4e-22 76.3 4.1 1.7e-21 75.3 2.9 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_4 PF13420.1 KEY67936.1 - 0.00011 22.2 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEY67936.1 - 0.00019 21.3 0.0 0.00045 20.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KEY67936.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEY67936.1 - 0.18 11.5 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Imm47 PF15586.1 KEY67936.1 - 0.23 11.2 0.0 0.44 10.4 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 47 Cpn60_TCP1 PF00118.19 KEY67938.1 - 5e-142 473.9 5.0 5.8e-142 473.7 3.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glyco_hydro_20 PF00728.17 KEY67939.1 - 1.6e-36 126.2 4.3 7.9e-36 123.9 3.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 KEY67939.1 - 6.6e-05 23.4 0.0 0.00019 21.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Acetyltransf_1 PF00583.19 KEY67940.1 - 1.4e-05 25.0 0.0 2.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEY67940.1 - 3.8e-05 23.7 0.0 8.5e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CorA PF01544.13 KEY67940.1 - 0.0019 17.3 0.3 0.0029 16.6 0.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Acetyltransf_10 PF13673.1 KEY67940.1 - 0.03 14.4 0.0 0.082 13.0 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain EamA PF00892.15 KEY67940.1 - 0.067 13.2 3.1 0.13 12.2 2.2 1.4 1 0 0 1 1 1 0 EamA-like transporter family Endonuc-EcoRV PF09233.6 KEY67940.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease EcoRV MFS_1 PF07690.11 KEY67941.1 - 3.1e-27 95.2 60.8 6.9e-19 67.7 23.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY67941.1 - 0.00012 20.8 45.1 0.0008 18.0 5.4 3.4 2 2 1 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.8 KEY67941.1 - 0.27 9.3 15.8 0.061 11.4 2.2 2.4 2 1 0 2 2 2 0 Transmembrane secretion effector AIM24 PF01987.12 KEY67942.1 - 6.2e-46 156.5 0.0 8e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF4402 PF14352.1 KEY67942.1 - 0.35 11.3 2.2 0.87 10.0 1.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4402) Kinesin PF00225.18 KEY67943.1 - 1.1e-81 274.1 0.0 1.5e-81 273.7 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain UPF0184 PF03670.8 KEY67943.1 - 0.0026 17.8 0.4 3.8 7.7 0.1 2.8 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0184) PBP1_TM PF14812.1 KEY67943.1 - 0.014 15.6 0.3 0.043 14.1 0.2 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MtrG PF04210.8 KEY67943.1 - 0.047 13.3 0.1 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G HHH_3 PF12836.2 KEY67943.1 - 0.076 12.9 0.4 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif Proteasome_A_N PF10584.4 KEY67945.1 - 0.045 13.0 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Peptidase_S8 PF00082.17 KEY67946.1 - 9.6e-42 143.0 0.1 1.3e-41 142.5 0.1 1.2 1 0 0 1 1 1 1 Subtilase family Zip PF02535.17 KEY67947.1 - 1.1e-25 90.3 44.6 3.8e-11 42.5 3.7 4.1 3 1 1 4 4 4 3 ZIP Zinc transporter MutS_V PF00488.16 KEY67948.1 - 3.8e-95 317.7 0.0 5.5e-95 317.2 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KEY67948.1 - 1.1e-38 133.0 0.3 2.8e-38 131.7 0.2 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 KEY67948.1 - 6.5e-23 81.3 0.9 5.7e-21 75.0 0.0 2.9 2 1 0 2 2 2 1 MutS domain II MutS_I PF01624.15 KEY67948.1 - 3.4e-17 62.4 0.0 1.4e-16 60.4 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 KEY67948.1 - 3.1e-11 43.3 2.4 5.4e-11 42.5 0.4 2.6 3 0 0 3 3 3 1 MutS family domain IV AAA_22 PF13401.1 KEY67948.1 - 0.02 15.0 0.0 0.26 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Tim17 PF02466.14 KEY67949.1 - 1.6e-06 28.1 8.1 3.8e-06 26.9 5.6 1.6 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.4 KEY67949.1 - 1.9 8.6 8.3 0.39 10.8 1.4 2.2 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide tRNA_m1G_MT PF01746.16 KEY67950.1 - 6e-32 110.7 0.1 9.5e-26 90.5 0.0 2.3 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase HD_5 PF13487.1 KEY67950.1 - 0.059 13.3 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 HD domain DNA_primase_S PF01896.14 KEY67951.1 - 9.3e-53 177.9 0.4 9.3e-53 177.9 0.3 1.8 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase small subunit MIP PF00230.15 KEY67952.1 - 8.5e-41 139.8 4.5 1.1e-40 139.4 3.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein MMR_HSR1 PF01926.18 KEY67953.1 - 3.9e-10 39.7 0.3 9.5e-10 38.4 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KEY67953.1 - 9.4e-06 24.8 0.2 1.9e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 AIG1 family Septin PF00735.13 KEY67953.1 - 0.00013 21.0 0.1 0.00013 21.0 0.1 1.6 2 0 0 2 2 2 1 Septin Miro PF08477.8 KEY67953.1 - 0.00023 21.6 0.3 0.0012 19.3 0.1 2.2 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 KEY67953.1 - 0.00053 19.2 1.1 0.0011 18.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 KEY67953.1 - 0.0006 19.1 0.1 0.0015 17.7 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KEY67953.1 - 0.00064 19.5 5.5 0.28 10.9 0.2 3.1 2 1 1 3 3 3 2 Dynamin family ABC_tran PF00005.22 KEY67953.1 - 0.0042 17.3 0.6 0.01 16.1 0.0 2.0 2 0 0 2 2 2 1 ABC transporter NB-ARC PF00931.17 KEY67953.1 - 0.0059 15.5 1.1 0.0072 15.2 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain SRP54 PF00448.17 KEY67953.1 - 0.015 14.7 0.1 0.049 13.0 0.1 1.9 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 KEY67953.1 - 0.017 15.2 0.0 0.053 13.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 KEY67953.1 - 0.026 13.9 0.1 0.053 12.9 0.1 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KEY67953.1 - 0.031 14.1 0.2 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain VirE PF05272.6 KEY67953.1 - 0.037 13.5 0.4 4.7 6.6 0.0 2.6 2 1 0 2 2 2 0 Virulence-associated protein E IIGP PF05049.8 KEY67953.1 - 0.041 12.7 0.6 0.2 10.4 0.2 2.1 1 1 1 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_17 PF13207.1 KEY67953.1 - 0.042 14.6 1.5 0.072 13.9 0.2 1.9 2 1 0 2 2 1 0 AAA domain DGCR6 PF07324.6 KEY67953.1 - 0.046 13.2 3.6 0.082 12.3 2.5 1.3 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein MobB PF03205.9 KEY67953.1 - 0.069 12.8 0.8 0.17 11.6 0.6 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KEY67953.1 - 0.15 12.3 1.6 2.6 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 KEY67953.1 - 0.19 11.2 3.9 0.11 11.9 0.4 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein OmpH PF03938.9 KEY67953.1 - 0.83 9.5 8.2 0.082 12.8 1.9 2.1 2 1 0 2 2 1 0 Outer membrane protein (OmpH-like) NTPase_1 PF03266.10 KEY67953.1 - 2.1 8.0 7.0 1.3 8.7 0.4 2.8 3 0 0 3 3 3 0 NTPase DUF87 PF01935.12 KEY67953.1 - 4.1 7.1 8.0 0.84 9.3 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 HSF_DNA-bind PF00447.12 KEY67955.1 - 4.4e-33 113.5 0.1 7.8e-33 112.7 0.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 KEY67955.1 - 7.7e-21 74.1 0.0 1.8e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain DUF972 PF06156.8 KEY67955.1 - 0.18 12.1 1.8 0.4 11.0 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) W2 PF02020.13 KEY67957.1 - 7.5e-20 70.6 0.7 1.8e-19 69.4 0.5 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 KEY67957.1 - 5.4e-09 35.1 14.4 0.00021 20.6 5.0 4.3 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KEY67957.1 - 0.00034 20.1 14.9 0.062 12.8 0.5 3.5 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 KEY67957.1 - 0.0025 17.1 0.0 0.0037 16.5 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 KEY67957.1 - 0.0064 16.5 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF2410 PF10307.4 KEY67958.1 - 1.1e-77 259.8 0.0 1.5e-77 259.4 0.0 1.1 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) DUF167 PF02594.11 KEY67959.1 - 1e-17 63.7 0.1 1.6e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 CP2 PF04516.10 KEY67961.1 - 4.9e-83 277.8 0.0 7.1e-83 277.2 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor CG-1 PF03859.11 KEY67961.1 - 0.023 14.2 0.1 0.75 9.3 0.0 2.8 3 0 0 3 3 3 0 CG-1 domain Phage_G PF02306.10 KEY67961.1 - 0.024 14.2 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Major spike protein (G protein) Tektin PF03148.9 KEY67961.1 - 0.031 12.8 0.0 0.051 12.1 0.0 1.2 1 0 0 1 1 1 0 Tektin family MFS_1 PF07690.11 KEY67963.1 - 3e-31 108.4 37.9 3.4e-31 108.2 24.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF21 PF01595.15 KEY67963.1 - 0.43 9.8 6.8 21 4.3 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function DUF21 eIF2A PF08662.6 KEY67964.1 - 1.5e-78 263.0 0.0 6.9e-78 260.8 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A CDV3 PF15359.1 KEY67964.1 - 0.0019 18.2 2.6 0.0091 16.0 0.2 2.8 3 0 0 3 3 3 1 Carnitine deficiency-associated protein 3 RPAP1_C PF08620.5 KEY67965.1 - 1.3e-29 101.8 0.0 2.4e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 KEY67965.1 - 3.9e-16 58.3 4.7 6.3e-16 57.7 3.3 1.3 1 0 0 1 1 1 1 RPAP1-like, N-terminal GIDA_assoc_3 PF13932.1 KEY67965.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 GidA associated domain 3 DUF438 PF04282.8 KEY67965.1 - 0.087 12.6 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF438) Dimerisation PF08100.6 KEY67965.1 - 0.15 11.9 0.1 0.53 10.1 0.0 1.9 1 0 0 1 1 1 0 Dimerisation domain HUN PF08729.5 KEY67966.1 - 4.5e-12 45.6 0.1 1.2e-11 44.3 0.1 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain VHS PF00790.14 KEY67967.1 - 5.4e-45 152.4 0.0 2.6e-44 150.2 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 KEY67967.1 - 8.4e-24 83.4 0.1 2.3e-23 82.0 0.1 1.7 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 KEY67967.1 - 3e-18 66.2 0.0 9.2e-18 64.6 0.0 1.8 2 0 0 2 2 2 1 Adaptin C-terminal domain DUF367 PF04034.8 KEY67968.1 - 1.1e-46 157.6 0.0 1.5e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 KEY67968.1 - 2.2e-12 46.3 0.6 5.8e-12 44.9 0.4 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Daxx PF03344.10 KEY67968.1 - 0.00011 20.8 18.6 0.00015 20.4 12.9 1.1 1 0 0 1 1 1 1 Daxx Family Nop25 PF09805.4 KEY67968.1 - 7.4 6.6 16.8 3.6e+02 1.1 11.6 2.2 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF3449 PF11931.3 KEY67968.1 - 9.2 5.7 7.4 7.3 6.0 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) GTP_EFTU PF00009.22 KEY67969.1 - 7.6e-37 126.5 3.9 3.5e-36 124.4 2.7 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KEY67969.1 - 8.9e-27 93.1 1.7 2.6e-26 91.6 1.2 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KEY67969.1 - 1.3e-11 44.4 1.9 8.7e-08 32.1 0.2 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEY67969.1 - 1.1e-06 28.5 0.1 2.8e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.10 KEY67969.1 - 1.6e-06 27.6 0.1 3.7e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region PduV-EutP PF10662.4 KEY67969.1 - 5.4e-06 25.9 0.2 1.4e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 KEY67969.1 - 1.1e-05 25.8 0.1 2.8e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 KEY67969.1 - 0.00032 20.0 0.1 0.00068 18.9 0.1 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 KEY67969.1 - 0.0011 18.2 0.1 0.0028 16.8 0.1 1.8 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF3854 PF12965.2 KEY67969.1 - 0.012 15.2 0.3 0.033 13.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) GPP34 PF05719.6 KEY67971.1 - 1.3e-64 218.0 0.2 1.7e-64 217.6 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) K_channel_TID PF07941.6 KEY67971.1 - 0.94 9.7 5.1 0.18 12.0 0.8 1.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain SURF6 PF04935.7 KEY67972.1 - 1.1e-48 165.3 42.5 1.1e-48 165.3 29.5 4.1 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 KEY67972.1 - 5.9e-20 71.0 1.6 5.9e-20 71.0 1.1 7.9 6 2 1 7 7 7 1 60S ribosome biogenesis protein Rrp14 Lentiviral_Tat PF02998.9 KEY67972.1 - 3 7.7 9.4 0.41 10.4 3.0 2.2 2 0 0 2 2 2 0 Lentiviral Tat protein PP28 PF10252.4 KEY67973.1 - 4.3e-27 93.9 19.6 4.3e-27 93.9 13.6 3.3 2 1 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 Cut8_N PF14482.1 KEY67973.1 - 1.3 9.0 7.7 4.4 7.3 1.0 2.6 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Anophelin PF10731.4 KEY67973.1 - 10 6.3 15.5 0.7 10.0 0.5 2.7 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito CoA_trans PF01144.18 KEY67975.1 - 1.2e-99 331.8 1.6 6.3e-61 205.3 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase Nrap PF03813.9 KEY67976.1 - 0 1011.5 0.0 0 1011.3 0.0 1.0 1 0 0 1 1 1 1 Nrap protein DUF1819 PF08849.6 KEY67976.1 - 0.032 13.6 0.1 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 Putative inner membrane protein (DUF1819) I-set PF07679.11 KEY67977.1 - 2.9e-05 23.8 0.1 1.4 8.8 0.0 5.2 5 1 0 5 5 5 2 Immunoglobulin I-set domain DUF1918 PF08940.6 KEY67977.1 - 0.00032 19.9 0.7 0.75 9.1 0.0 4.9 5 0 0 5 5 5 2 Domain of unknown function (DUF1918) Peptidase_C12 PF01088.16 KEY67978.1 - 9.7e-51 171.9 0.1 7.7e-49 165.7 0.1 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF3408 PF11888.3 KEY67978.1 - 0.032 14.1 0.4 0.032 14.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Transglut_core2 PF13369.1 KEY67979.1 - 6.6e-22 77.6 0.0 1.2e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 KEY67979.1 - 1.6e-08 34.1 0.9 3.5e-08 33.0 0.7 1.6 1 0 0 1 1 1 1 F-box-like YccV-like PF08755.6 KEY67979.1 - 8.4e-05 22.4 0.0 0.0002 21.2 0.0 1.7 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like F-box PF00646.28 KEY67979.1 - 0.00017 21.1 0.1 0.00047 19.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain FBA PF04300.8 KEY67979.1 - 0.057 13.3 0.1 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 F-box associated region Elongin_A PF06881.6 KEY67979.1 - 0.069 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Peptidase_M9_N PF08453.5 KEY67979.1 - 0.083 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M9 N-terminal AAA_12 PF13087.1 KEY67979.1 - 0.19 11.1 0.1 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Microtub_assoc PF07989.6 KEY67980.1 - 2.3e-28 97.8 2.5 2.3e-28 97.8 1.7 15.0 9 4 8 18 18 18 1 Microtubule associated PACT_coil_coil PF10495.4 KEY67980.1 - 2.7e-09 36.8 0.5 1.5e-08 34.4 0.3 2.4 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein AAA_13 PF13166.1 KEY67980.1 - 1.5e-07 30.3 25.2 1.5e-07 30.3 17.5 6.0 2 1 4 6 6 6 5 AAA domain ADIP PF11559.3 KEY67980.1 - 0.00015 21.6 13.5 0.00015 21.6 9.4 13.7 3 3 8 13 13 13 2 Afadin- and alpha -actinin-Binding MscS_porin PF12795.2 KEY67980.1 - 0.00058 19.2 27.9 0.00058 19.2 19.3 7.8 2 1 4 7 7 7 3 Mechanosensitive ion channel porin domain Tropomyosin_1 PF12718.2 KEY67980.1 - 0.0031 17.3 29.7 0.0031 17.3 20.6 12.6 1 1 11 14 14 14 2 Tropomyosin like TPR_MLP1_2 PF07926.7 KEY67980.1 - 0.006 16.3 8.2 0.006 16.3 5.7 13.8 1 1 11 12 12 12 4 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 KEY67980.1 - 0.029 13.5 58.3 0.034 13.3 0.8 8.1 1 1 5 8 8 8 0 Reovirus sigma C capsid protein Spc7 PF08317.6 KEY67980.1 - 0.65 8.6 188.5 0.0052 15.4 5.9 10.3 2 1 10 12 12 12 0 Spc7 kinetochore protein IncA PF04156.9 KEY67980.1 - 0.84 9.1 243.9 0.19 11.3 22.8 11.1 3 2 9 12 12 12 0 IncA protein Peptidase_C14 PF00656.17 KEY67981.1 - 2.9e-72 243.3 0.0 3.8e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DUF605 PF04652.11 KEY67981.1 - 1.3 8.2 20.9 2.1 7.6 14.5 1.4 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 KEY67981.1 - 2 8.2 10.5 3.7 7.3 7.3 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 KEY67981.1 - 9 4.3 28.1 12 3.9 19.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SKG6 PF08693.5 KEY67984.1 - 0.007 15.6 2.4 0.007 15.6 1.7 2.2 2 1 0 2 2 2 1 Transmembrane alpha-helix domain Shisa PF13908.1 KEY67984.1 - 0.031 14.4 0.0 0.036 14.2 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF755 PF05501.6 KEY67984.1 - 3.5 7.6 9.2 5.3 7.1 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SNF2_N PF00176.18 KEY67985.1 - 1.3e-69 234.3 0.0 1.8e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KEY67985.1 - 3.6e-21 75.1 0.0 7.4e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 KEY67985.1 - 7e-13 48.2 0.0 1.6e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KEY67985.1 - 1.5e-05 24.9 9.8 3.1e-05 23.9 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KEY67985.1 - 3.2e-05 23.8 0.0 8.9e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 KEY67985.1 - 0.0009 18.8 9.5 0.0018 17.8 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEY67985.1 - 0.0024 17.5 8.1 0.0045 16.6 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) AAA_22 PF13401.1 KEY67985.1 - 0.007 16.5 0.0 0.16 12.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain zf-RING_5 PF14634.1 KEY67985.1 - 0.03 14.0 8.0 0.099 12.3 5.6 1.9 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 KEY67985.1 - 0.031 14.0 10.7 0.073 12.9 7.4 1.7 1 0 0 1 1 1 0 Ring finger domain UBA_4 PF14555.1 KEY67985.1 - 0.054 13.0 0.2 0.49 9.9 0.0 2.5 2 0 0 2 2 2 0 UBA-like domain SQS_PSY PF00494.14 KEY67986.1 - 6.2e-52 176.5 0.0 8.5e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Ribosomal_S6 PF01250.12 KEY67986.1 - 2.5e-10 40.0 0.0 4.2e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6 Cullin_binding PF03556.10 KEY67987.1 - 1.9e-32 111.8 2.8 1.9e-32 111.8 2.0 1.6 2 0 0 2 2 2 1 Cullin binding BRCT PF00533.21 KEY67988.1 - 3e-43 145.8 0.7 1.4e-12 47.6 0.0 4.7 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KEY67988.1 - 2e-42 142.8 0.6 5.9e-16 58.0 0.1 4.1 4 0 0 4 4 4 3 twin BRCT domain MFS_1 PF07690.11 KEY67989.1 - 1.1e-11 44.1 36.1 1e-07 30.9 15.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily NifU_N PF01592.11 KEY67989.1 - 0.035 14.0 0.6 3.8 7.4 0.0 2.2 2 0 0 2 2 2 0 NifU-like N terminal domain DUF3716 PF12511.3 KEY67990.1 - 1.7e-10 40.3 8.3 3.1e-10 39.4 5.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) V_ATPase_I PF01496.14 KEY67990.1 - 0.76 7.5 3.7 1.2 6.9 2.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KEY67990.1 - 1.7 8.2 9.7 4.2 6.9 6.7 1.6 1 0 0 1 1 1 0 IncA protein IFP_35_N PF07334.8 KEY67990.1 - 2.1 8.3 5.6 4.2 7.4 0.9 2.8 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Chs3p PF12271.3 KEY67991.1 - 3e-138 459.7 13.0 3.5e-138 459.5 9.0 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3382 PF11862.3 KEY67991.1 - 0.0012 18.7 1.7 0.0012 18.7 1.2 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3382) SIR2 PF02146.12 KEY67992.1 - 4.7e-34 117.6 0.0 1.7e-32 112.5 0.0 2.1 1 1 0 1 1 1 1 Sir2 family UvrD-helicase PF00580.16 KEY67992.1 - 0.012 14.8 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Acetyltransf_1 PF00583.19 KEY67993.1 - 9.9e-10 38.3 0.0 1.7e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEY67993.1 - 1.3e-05 25.2 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyoxalase PF00903.20 KEY67993.1 - 0.0044 16.9 0.0 0.0064 16.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Acetyltransf_10 PF13673.1 KEY67993.1 - 0.013 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 KEY67993.1 - 0.069 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PIG-L PF02585.12 KEY67994.1 - 4.8e-27 94.9 0.1 7.6e-27 94.3 0.1 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF202 PF02656.10 KEY67996.1 - 0.072 13.3 0.2 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF3552 PF12072.3 KEY67996.1 - 6.8 5.8 8.7 0.26 10.4 2.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) ADH_zinc_N PF00107.21 KEY67997.1 - 1.3e-19 70.0 0.0 2e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY67997.1 - 1.9e-09 38.5 0.1 2.4e-08 34.9 0.0 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase PhoH PF02562.11 KEY67997.1 - 0.061 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Nha1_C PF08619.5 KEY67998.1 - 6.4e-71 239.9 21.1 7.9e-71 239.5 14.6 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 KEY67998.1 - 2e-64 217.4 21.0 2.4e-64 217.2 14.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FlgD_ig PF13860.1 KEY67998.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 FlgD Ig-like domain YrhC PF14143.1 KEY67998.1 - 1.9 8.5 5.2 0.47 10.4 0.2 2.4 2 0 0 2 2 2 0 YrhC-like protein SH3_1 PF00018.23 KEY68000.1 - 1.7e-09 36.8 0.1 2.6e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KEY68000.1 - 2.5e-07 30.0 0.0 5.9e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KEY68000.1 - 5.3e-07 29.1 0.0 1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DASH_Spc19 PF08287.6 KEY68001.1 - 7.6e-34 116.5 5.1 1.9e-21 76.2 0.8 2.5 1 1 1 2 2 2 2 Spc19 Thioredoxin_6 PF13848.1 KEY68001.1 - 0.058 13.1 0.0 0.075 12.8 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain FlaC_arch PF05377.6 KEY68001.1 - 0.21 11.4 1.2 4.8 7.1 0.0 3.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) ADIP PF11559.3 KEY68001.1 - 0.22 11.4 2.4 3.1 7.6 1.5 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding COG5 PF10392.4 KEY68001.1 - 0.3 11.0 2.9 1.5 8.7 0.2 2.8 2 1 1 3 3 3 0 Golgi transport complex subunit 5 GPI-anchored PF10342.4 KEY68002.1 - 0.023 15.1 0.5 0.14 12.6 0.3 2.0 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1399 PF07173.7 KEY68003.1 - 4.4e-17 62.6 0.1 1.8e-16 60.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1399) Ribosomal_L44 PF00935.14 KEY68003.1 - 0.032 14.2 0.5 0.068 13.1 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L44 PCI PF01399.22 KEY68004.1 - 1.3e-21 76.9 0.0 3.5e-21 75.4 0.0 1.8 1 0 0 1 1 1 1 PCI domain Asp_Glu_race_2 PF14669.1 KEY68004.1 - 7.1e-05 22.2 2.2 0.057 12.7 0.1 2.3 1 1 1 2 2 2 2 Putative aspartate racemase MRP-L51 PF10244.4 KEY68004.1 - 0.067 13.2 0.6 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit FSH1 PF03959.8 KEY68005.1 - 5.4e-59 199.2 0.0 6.5e-59 198.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KEY68005.1 - 3.5e-09 36.8 0.9 1.6e-06 28.1 0.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY68005.1 - 1.1e-07 31.7 0.0 1.4e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KEY68005.1 - 0.0023 17.2 0.1 0.21 10.7 0.2 2.4 2 0 0 2 2 2 1 Esterase PHB depolymerase PE-PPE PF08237.6 KEY68005.1 - 0.0088 15.4 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.11 KEY68005.1 - 0.11 11.8 3.0 20 4.5 0.0 3.1 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase AXE1 PF05448.7 KEY68005.1 - 0.31 9.4 1.0 1 7.8 0.3 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) ATP-synt_J PF04911.7 KEY68006.1 - 2.7e-24 84.3 0.6 3e-24 84.2 0.4 1.0 1 0 0 1 1 1 1 ATP synthase j chain NIPSNAP PF07978.8 KEY68007.1 - 6.9e-39 131.9 0.7 2.8e-28 97.9 0.1 3.0 3 0 0 3 3 3 2 NIPSNAP ASD2 PF08687.6 KEY68007.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Rogdi_lz PF10259.4 KEY68008.1 - 4.1e-64 216.3 0.0 4.7e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rpp20 PF12328.3 KEY68009.1 - 1.2e-24 86.5 0.0 2e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 KEY68009.1 - 5.8e-13 48.2 0.0 8.8e-13 47.6 0.0 1.3 1 0 0 1 1 1 1 Alba DUF3237 PF11578.3 KEY68010.1 - 6.6e-05 22.2 0.0 0.00051 19.3 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) FMO-like PF00743.14 KEY68012.1 - 5.3e-36 123.9 0.0 5.9e-29 100.6 0.0 2.5 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KEY68012.1 - 3.5e-11 43.5 0.0 8e-08 32.5 0.0 3.5 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEY68012.1 - 7.7e-08 31.6 0.0 1.4e-05 24.1 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KEY68012.1 - 1.4e-05 24.9 2.2 0.15 11.8 0.0 3.9 4 1 1 5 5 5 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KEY68012.1 - 0.00033 20.6 0.0 0.0013 18.6 0.0 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Myb_DNA-bind_6 PF13921.1 KEY68013.1 - 3.2e-16 59.1 6.3 4.5e-11 42.6 0.3 3.8 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KEY68013.1 - 1e-14 54.2 6.7 2.6e-08 33.7 0.0 4.4 4 1 0 4 4 4 3 Myb-like DNA-binding domain Arch_ATPase PF01637.13 KEY68014.1 - 5.4e-08 32.8 0.2 8.2e-08 32.2 0.1 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 KEY68014.1 - 6.4e-07 29.5 0.3 2.4e-05 24.3 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain ATP-synt_ab PF00006.20 KEY68014.1 - 0.0012 18.3 0.0 0.0026 17.2 0.0 1.5 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.8 KEY68014.1 - 0.014 14.3 0.1 0.076 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 KEY68014.1 - 0.029 14.4 0.2 0.08 13.0 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KEY68014.1 - 0.053 12.9 0.3 0.19 11.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 KEY68014.1 - 0.074 13.5 0.1 1.2 9.6 0.0 2.6 2 1 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 KEY68014.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain Fungal_trans_2 PF11951.3 KEY68016.1 - 3.8e-33 114.6 1.7 7.1e-23 80.8 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY68016.1 - 1e-08 34.9 11.8 1.9e-08 34.0 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 KEY68016.1 - 0.071 12.8 4.6 0.2 11.4 3.2 1.8 1 0 0 1 1 1 0 AT hook motif Ank_2 PF12796.2 KEY68018.1 - 1.2e-66 221.1 24.6 9e-12 45.1 0.1 8.5 1 1 8 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEY68018.1 - 1.3e-43 146.5 12.2 1.2e-05 25.7 0.0 10.9 9 3 4 13 13 13 10 Ankyrin repeats (many copies) Ank PF00023.25 KEY68018.1 - 3e-38 127.7 28.2 0.001 18.7 0.0 15.9 15 0 0 15 15 15 9 Ankyrin repeat Ank_3 PF13606.1 KEY68018.1 - 1.6e-32 108.2 24.4 0.00036 20.5 0.0 16.2 18 0 0 18 18 18 6 Ankyrin repeat Ank_5 PF13857.1 KEY68018.1 - 1.3e-27 95.1 26.3 1.5e-06 28.2 0.0 13.5 5 4 9 15 15 15 8 Ankyrin repeats (many copies) Abhydrolase_6 PF12697.2 KEY68018.1 - 4.6e-05 23.4 0.7 4.6e-05 23.4 0.5 2.6 3 0 0 3 3 3 1 Alpha/beta hydrolase family Cutinase PF01083.17 KEY68018.1 - 0.001 18.8 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Cutinase MFS_1 PF07690.11 KEY68019.1 - 7.2e-34 117.0 26.4 7.2e-34 117.0 18.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily NfeD PF01957.13 KEY68019.1 - 1.2 9.2 0.0 1.2 9.2 0.0 3.7 3 2 2 6 6 6 0 NfeD-like C-terminal, partner-binding VSP PF03302.8 KEY68020.1 - 0.00018 20.2 1.1 0.00018 20.2 0.8 2.1 2 0 0 2 2 2 1 Giardia variant-specific surface protein SKG6 PF08693.5 KEY68020.1 - 0.00064 18.9 0.0 0.0022 17.2 0.0 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MLANA PF14991.1 KEY68020.1 - 0.063 13.2 0.1 0.3 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein melan-A NAD_binding_6 PF08030.7 KEY68021.1 - 6e-33 113.9 0.0 1.1e-32 113.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KEY68021.1 - 4.3e-19 68.3 0.0 1.9e-18 66.2 0.0 2.1 2 1 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 KEY68021.1 - 3.6e-16 59.3 11.0 3.6e-16 59.3 7.6 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KEY68021.1 - 0.0064 16.5 0.0 0.023 14.8 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KEY68021.1 - 0.1 13.1 0.0 0.74 10.3 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4131 PF13567.1 KEY68021.1 - 2.4 7.5 6.1 0.37 10.1 1.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) UQ_con PF00179.21 KEY68022.1 - 6.9e-51 171.3 0.0 7.8e-51 171.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEY68022.1 - 5.7e-05 22.8 0.0 6.7e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KEY68022.1 - 0.0052 16.6 0.0 0.0057 16.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KEY68022.1 - 0.021 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain Acyl-CoA_dh_N PF02771.11 KEY68023.1 - 4.9e-24 85.0 1.0 1e-23 84.0 0.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 KEY68023.1 - 1.5e-22 80.3 0.1 2.6e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KEY68023.1 - 3.1e-15 55.4 0.0 6.8e-15 54.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KEY68023.1 - 1.3e-07 31.9 0.0 2.2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PIP5K PF01504.13 KEY68025.1 - 1.5e-83 279.7 0.7 2.2e-83 279.2 0.0 1.6 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase COX6B PF02297.12 KEY68026.1 - 2.3e-20 72.3 2.1 3e-20 72.0 1.5 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 KEY68026.1 - 0.14 12.2 0.3 0.23 11.5 0.2 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 SYS1 PF09801.4 KEY68027.1 - 4.2e-46 156.5 4.9 4.8e-46 156.3 3.4 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network CHD5 PF04420.9 KEY68027.1 - 0.15 11.7 1.4 0.24 11.0 1.0 1.3 1 0 0 1 1 1 0 CHD5-like protein TrbE PF11100.3 KEY68027.1 - 0.51 10.2 4.7 0.98 9.3 1.9 2.2 1 1 1 2 2 2 0 Conjugal transfer protein TrbE CPSF100_C PF13299.1 KEY68028.1 - 4.4e-39 134.2 1.4 7.2e-39 133.5 0.0 2.0 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 KEY68028.1 - 2.8e-27 95.1 0.0 1.1e-26 93.2 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.7 KEY68028.1 - 0.0013 18.4 0.0 0.0033 17.2 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Gti1_Pac2 PF09729.4 KEY68029.1 - 7.8e-49 165.7 1.3 1.2e-46 158.6 0.9 2.3 1 1 0 1 1 1 1 Gti1/Pac2 family PAT1 PF09770.4 KEY68029.1 - 9.1 4.3 29.8 14 3.7 20.7 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ABM PF03992.11 KEY68030.1 - 0.00011 22.1 0.4 0.63 10.1 0.0 2.8 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Dehydratase_hem PF13816.1 KEY68030.1 - 0.03 13.3 0.2 0.043 12.8 0.1 1.3 1 1 0 1 1 1 0 Haem-containing dehydratase Ribosomal_L38e PF01781.13 KEY68031.1 - 1.6e-33 114.2 4.6 1.8e-33 114.0 3.2 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Ish1 PF10281.4 KEY68032.1 - 0.0036 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein DUF1470 PF07336.6 KEY68032.1 - 0.039 14.2 4.7 0.058 13.7 3.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1470) Metal_resist PF13801.1 KEY68032.1 - 0.054 13.4 1.3 0.068 13.1 0.9 1.2 1 0 0 1 1 1 0 Heavy-metal resistance DUF4538 PF15061.1 KEY68032.1 - 0.1 11.9 0.4 0.16 11.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) UCR_Fe-S_N PF10399.4 KEY68032.1 - 3.8 6.7 5.6 8 5.7 3.9 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal NMO PF03060.10 KEY68034.1 - 3.9e-65 220.1 0.1 4.7e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KEY68034.1 - 6.1e-07 28.6 0.0 0.0092 14.8 0.0 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KEY68034.1 - 0.0024 16.7 1.4 0.0042 15.9 1.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DEAD PF00270.24 KEY68035.1 - 3.9e-44 150.1 0.0 1.1e-43 148.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY68035.1 - 4.2e-21 74.5 0.0 9.9e-21 73.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KEY68035.1 - 5.9e-20 70.5 0.1 1.1e-19 69.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Sigma70_ner PF04546.8 KEY68035.1 - 1.3 8.6 4.6 2.7 7.5 3.2 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region FAD_binding_4 PF01565.18 KEY68036.1 - 6.9e-17 61.2 0.2 1.3e-16 60.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_31 PF01055.21 KEY68038.1 - 4e-165 549.9 1.3 4.8e-165 549.6 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KEY68038.1 - 6.9e-10 38.6 1.2 2.2e-09 37.0 0.8 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Fungal_trans PF04082.13 KEY68039.1 - 5.1e-17 61.5 1.4 8.2e-17 60.9 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY68039.1 - 3.2e-16 58.9 24.4 9.4e-09 35.0 4.7 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain PARP PF00644.15 KEY68041.1 - 3.5e-60 202.9 0.0 7.4e-60 201.8 0.0 1.6 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 KEY68041.1 - 6.2e-41 139.1 0.3 9.6e-41 138.5 0.2 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 KEY68041.1 - 7.5e-19 67.4 0.2 1.6e-18 66.4 0.1 1.6 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 KEY68041.1 - 2.1e-14 53.4 0.0 3.9e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KEY68041.1 - 1.6e-05 24.7 0.0 3.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain F-box PF00646.28 KEY68042.1 - 0.0026 17.3 0.0 0.0089 15.6 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KEY68042.1 - 0.018 14.7 0.1 0.049 13.3 0.0 1.7 1 0 0 1 1 1 0 F-box-like Phospholip_A2_3 PF09056.6 KEY68042.1 - 0.096 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic phospholipase A2 Nucleoplasmin PF03066.10 KEY68042.1 - 0.22 11.0 2.7 0.35 10.3 1.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin Hap4_Hap_bind PF10297.4 KEY68043.1 - 2.3e-08 33.5 7.1 2.3e-08 33.5 4.9 2.2 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 KEY68043.1 - 1.3e-06 28.2 6.5 4.9e-06 26.3 4.5 2.0 1 0 0 1 1 1 1 bZIP transcription factor Bacillus_HBL PF05791.6 KEY68043.1 - 0.11 11.8 0.7 0.3 10.4 0.5 1.7 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) HAUS6_N PF14661.1 KEY68043.1 - 0.36 10.1 8.1 0.29 10.4 4.2 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus COG2 PF06148.6 KEY68044.1 - 6.4e-26 90.7 1.3 9.5e-26 90.2 0.9 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 KEY68044.1 - 0.00089 19.0 0.5 0.0033 17.2 0.1 2.1 1 1 1 2 2 2 1 Vps51/Vps67 COG5 PF10392.4 KEY68044.1 - 0.0035 17.2 0.6 0.0088 16.0 0.4 1.7 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Spc7 PF08317.6 KEY68044.1 - 0.0043 15.7 2.7 0.0068 15.1 1.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Sec5 PF15469.1 KEY68044.1 - 0.016 14.9 1.1 0.039 13.6 0.2 1.9 2 0 0 2 2 2 0 Exocyst complex component Sec5 Zw10 PF06248.8 KEY68044.1 - 0.025 12.7 0.6 0.036 12.2 0.4 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Atg14 PF10186.4 KEY68044.1 - 0.037 12.9 4.4 0.073 12.0 3.0 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2450 PF10475.4 KEY68044.1 - 0.048 12.5 0.4 0.075 11.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Dor1 PF04124.7 KEY68044.1 - 0.053 11.9 2.3 0.076 11.4 1.6 1.2 1 0 0 1 1 1 0 Dor1-like family TPR_MLP1_2 PF07926.7 KEY68044.1 - 0.14 11.8 5.3 2.3 7.9 1.4 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF745 PF05335.8 KEY68044.1 - 0.16 11.4 2.9 3.6 7.0 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) IncA PF04156.9 KEY68044.1 - 2.3 7.7 8.3 13 5.3 5.7 2.0 1 1 0 1 1 1 0 IncA protein DUF4611 PF15387.1 KEY68044.1 - 3.2 7.9 7.3 3 8.0 3.5 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4611) Ribosomal_L1 PF00687.16 KEY68045.1 - 1.1e-27 96.8 0.0 1.9e-27 96.0 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family tRNA-synt_1c PF00749.16 KEY68046.1 - 4.6e-100 334.3 0.0 5.9e-100 333.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KEY68046.1 - 3.5e-38 130.9 0.0 6.6e-38 130.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 KEY68046.1 - 0.0011 19.3 0.0 0.0034 17.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 KEY68046.1 - 0.048 12.7 0.2 0.13 11.3 0.1 1.5 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain SBF PF01758.11 KEY68047.1 - 1.3e-46 158.3 8.5 1.3e-46 158.3 5.9 2.2 2 1 0 2 2 2 1 Sodium Bile acid symporter family TAFII28 PF04719.9 KEY68049.1 - 6.3e-22 77.1 0.1 2.7e-20 71.9 0.0 2.2 2 0 0 2 2 2 1 hTAFII28-like protein conserved region Cwf_Cwc_15 PF04889.7 KEY68049.1 - 0.021 14.5 1.8 0.028 14.1 1.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.6 KEY68049.1 - 0.73 9.3 5.2 1.1 8.6 3.6 1.2 1 0 0 1 1 1 0 PPP4R2 PBP1_TM PF14812.1 KEY68049.1 - 1.2 9.4 6.0 2.7 8.3 4.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TT_ORF2 PF02957.10 KEY68049.1 - 9.4 6.9 12.2 4.3 8.0 6.0 2.2 2 1 0 2 2 2 0 TT viral ORF2 PLU-1 PF08429.6 KEY68050.1 - 3.7e-99 331.8 10.5 1.2e-95 320.3 7.2 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 KEY68050.1 - 4.7e-43 146.0 0.2 1.1e-42 144.8 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 KEY68050.1 - 1.4e-25 88.9 0.0 3.9e-25 87.5 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 KEY68050.1 - 1.8e-15 56.3 21.9 5.3e-10 38.8 2.8 4.0 3 1 1 4 4 4 2 PHD-finger JmjN PF02375.12 KEY68050.1 - 5e-14 51.5 1.3 1e-13 50.5 0.9 1.6 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 KEY68050.1 - 1.2e-13 50.8 6.3 4.6e-13 49.0 4.4 2.1 1 0 0 1 1 1 1 C5HC2 zinc finger PHD_2 PF13831.1 KEY68050.1 - 0.00029 20.0 0.6 0.00029 20.0 0.4 2.8 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.1 KEY68050.1 - 0.00035 19.9 5.0 0.015 14.5 0.1 2.7 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain GIY-YIG PF01541.19 KEY68051.1 - 1.1e-08 35.2 0.0 2.2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H_2 PF13832.1 KEY68051.1 - 0.012 15.6 2.2 0.012 15.6 1.5 1.7 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KEY68051.1 - 0.015 15.4 3.0 0.015 15.4 2.1 1.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain T5orf172 PF10544.4 KEY68051.1 - 0.027 14.8 0.0 0.074 13.4 0.0 1.8 1 0 0 1 1 1 0 T5orf172 domain DiS_P_DiS PF06750.8 KEY68051.1 - 0.089 12.5 0.5 3.9 7.3 0.1 2.7 3 0 0 3 3 3 0 Bacterial Peptidase A24 N-terminal domain Prok-RING_1 PF14446.1 KEY68051.1 - 5.7 6.7 10.1 1.3 8.8 1.8 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 DUF3449 PF11931.3 KEY68052.1 - 6e-73 244.5 1.0 1.8e-72 242.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 KEY68052.1 - 8.2e-09 34.8 0.1 1.8e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 KEY68052.1 - 4.4e-08 33.0 2.3 2.6e-06 27.4 0.4 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KEY68052.1 - 4.3e-06 26.6 5.7 4.8e-06 26.5 0.4 2.6 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KEY68052.1 - 0.0014 18.6 1.2 0.02 14.9 0.2 2.6 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KEY68052.1 - 0.048 14.0 4.1 0.67 10.4 0.5 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF951 PF06107.6 KEY68052.1 - 0.057 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) zf-C2H2_4 PF13894.1 KEY68052.1 - 0.35 11.3 4.1 7.1 7.2 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-DBF PF07535.7 KEY68052.1 - 0.51 10.0 5.8 0.091 12.4 0.3 2.5 2 1 0 2 2 2 0 DBF zinc finger DEAD PF00270.24 KEY68053.1 - 9.4e-41 139.1 0.3 2.4e-40 137.7 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY68053.1 - 5.2e-29 99.9 0.2 1e-28 98.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 KEY68053.1 - 0.011 15.0 0.4 0.019 14.2 0.1 1.5 2 0 0 2 2 2 0 SecA DEAD-like domain AAA_19 PF13245.1 KEY68053.1 - 0.016 14.9 0.5 0.046 13.4 0.1 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 KEY68053.1 - 0.018 14.6 0.7 0.041 13.4 0.5 1.5 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 KEY68053.1 - 0.028 14.2 0.1 0.075 12.8 0.1 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 KEY68053.1 - 0.059 13.1 0.2 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.1 KEY68053.1 - 0.1 12.7 0.8 0.46 10.6 0.5 2.0 1 1 0 1 1 1 0 AAA domain tRNA-synt_1g PF09334.6 KEY68055.1 - 9.4e-132 439.3 5.4 2.7e-130 434.5 3.8 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KEY68055.1 - 1e-06 27.1 0.2 0.013 13.5 0.0 3.5 2 2 1 4 4 4 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KEY68055.1 - 0.00067 19.4 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DUF1688 PF07958.6 KEY68056.1 - 2.3e-166 553.4 0.0 5.2e-165 549.0 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1688) 60KD_IMP PF02096.15 KEY68057.1 - 1.2e-27 96.8 1.8 1.7e-27 96.3 1.2 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein TOM13 PF08219.6 KEY68058.1 - 6.3e-31 105.9 0.0 8.2e-31 105.6 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 SEP PF08059.8 KEY68059.1 - 7.8e-27 93.3 0.1 1.4e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 KEY68059.1 - 3.3e-11 43.0 0.0 5.6e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 KEY68059.1 - 5.9e-11 41.7 0.0 9e-11 41.1 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 KEY68059.1 - 0.083 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 UBA/TS-N domain Gtr1_RagA PF04670.7 KEY68060.1 - 4e-88 294.4 0.0 8.2e-88 293.4 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KEY68060.1 - 9.3e-07 28.3 0.2 6e-06 25.7 0.1 2.1 1 1 0 1 1 1 1 Ras family Arf PF00025.16 KEY68060.1 - 1.6e-06 27.4 0.4 3.6e-05 23.0 0.2 2.7 1 1 1 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 KEY68060.1 - 5.3e-05 23.6 0.0 0.00013 22.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 KEY68060.1 - 0.00064 19.1 0.6 0.0052 16.2 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KEY68060.1 - 0.0029 17.5 0.0 0.007 16.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 KEY68060.1 - 0.0056 16.9 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter GTP_EFTU PF00009.22 KEY68060.1 - 0.0094 15.4 0.0 0.019 14.3 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 KEY68060.1 - 0.016 13.9 0.4 0.37 9.4 0.1 2.3 2 0 0 2 2 2 0 G-protein alpha subunit DUF258 PF03193.11 KEY68060.1 - 0.027 13.6 0.1 0.041 13.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 DUF815 PF05673.8 KEY68060.1 - 0.05 12.5 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_10 PF12846.2 KEY68060.1 - 0.084 12.2 0.0 0.11 11.8 0.0 1.3 1 1 0 1 1 1 0 AAA-like domain Sigma54_activat PF00158.21 KEY68060.1 - 0.15 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain MFS_1 PF07690.11 KEY68063.1 - 5.3e-25 87.8 47.4 5.7e-24 84.4 17.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY68063.1 - 6.3e-25 87.6 25.8 2.8e-22 78.9 17.9 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Pec_lyase_C PF00544.14 KEY68064.1 - 1.4e-38 132.4 6.5 2.5e-38 131.5 4.5 1.5 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KEY68064.1 - 0.00011 22.0 11.7 0.0016 18.2 8.1 2.2 1 1 0 1 1 1 1 Right handed beta helix region SWIM PF04434.12 KEY68064.1 - 0.029 13.8 0.1 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 SWIM zinc finger Glyco_transf_21 PF13506.1 KEY68065.1 - 8.7e-14 51.1 0.1 4.1e-06 26.1 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 21 tRNA_int_endo PF01974.12 KEY68066.1 - 6.4e-19 67.5 0.1 3.1e-18 65.3 0.0 2.0 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 KEY68066.1 - 3.3e-05 23.3 0.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Prenyltrans PF00432.16 KEY68067.1 - 1.3e-27 95.0 12.7 4.4e-10 38.9 0.1 5.4 5 1 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 KEY68067.1 - 1.2e-24 86.3 0.1 2e-11 43.8 0.0 5.5 4 2 1 5 5 5 4 Prenyltransferase-like Prenyltrans_2 PF13249.1 KEY68067.1 - 2.1e-24 86.1 0.6 9.4e-16 58.2 0.0 4.5 3 2 0 4 4 4 3 Prenyltransferase-like Pec_lyase PF09492.5 KEY68067.1 - 0.00072 18.8 0.2 1.1 8.4 0.0 4.2 3 1 1 4 4 4 1 Pectic acid lyase Chromadorea_ALT PF05535.7 KEY68067.1 - 0.014 15.4 0.0 0.045 13.8 0.0 1.8 1 0 0 1 1 1 0 Chromadorea ALT protein A2M_comp PF07678.9 KEY68067.1 - 0.059 12.5 0.0 1.6 7.9 0.0 2.8 2 1 1 3 3 3 0 A-macroglobulin complement component SGS PF05002.10 KEY68068.1 - 7.4e-27 92.9 0.9 2.1e-26 91.4 0.6 1.8 1 0 0 1 1 1 1 SGS domain CS PF04969.11 KEY68068.1 - 3.9e-12 46.5 0.2 7e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 KEY68068.1 - 1.8e-09 37.0 1.2 3.8e-06 26.4 0.0 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KEY68068.1 - 1.7e-06 27.5 6.4 0.041 13.8 0.2 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEY68068.1 - 2e-06 27.1 0.4 0.019 14.5 0.3 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEY68068.1 - 4.1e-06 27.3 4.4 0.0026 18.3 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEY68068.1 - 0.033 14.7 4.6 8.5 7.3 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEY68068.1 - 0.037 13.8 0.0 7.8 6.5 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEY68068.1 - 0.037 14.4 0.3 4.7 7.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KEY68068.1 - 0.97 10.0 7.7 10 6.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TauD PF02668.11 KEY68069.1 - 7.2e-50 170.0 0.0 1.3e-49 169.2 0.0 1.5 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 KEY68069.1 - 0.0011 19.3 0.0 0.0032 17.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.5 KEY68069.1 - 0.027 13.3 0.0 0.065 12.1 0.0 1.5 2 0 0 2 2 2 0 CsiD TP6A_N PF04406.9 KEY68070.1 - 2.1e-20 72.1 0.9 4.2e-20 71.1 0.2 1.9 2 0 0 2 2 2 1 Type IIB DNA topoisomerase Ank_2 PF12796.2 KEY68071.1 - 2.7e-24 85.3 1.9 5.2e-15 55.5 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEY68071.1 - 2.5e-16 59.3 1.0 7e-10 38.8 0.5 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KEY68071.1 - 1.7e-15 55.8 1.4 6e-09 35.2 0.7 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KEY68071.1 - 3.4e-12 45.3 0.5 4.2e-06 26.4 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KEY68071.1 - 1.2e-10 41.6 0.1 4.5e-05 23.8 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) DUF1110 PF06533.7 KEY68071.1 - 0.0011 18.7 1.8 0.13 12.0 0.2 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1110) Fungal_trans PF04082.13 KEY68072.1 - 9.7e-51 172.1 0.0 1.4e-50 171.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KEY68072.1 - 1.2e-07 31.6 6.2 0.0048 17.1 1.2 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY68072.1 - 3e-06 27.1 5.8 0.0014 18.7 1.2 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEY68072.1 - 0.0045 17.2 0.3 0.0045 17.2 0.2 3.4 3 0 0 3 3 3 1 Zinc-finger double domain PIP5K PF01504.13 KEY68073.1 - 6.6e-33 113.8 0.0 8.5e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF2828 PF11443.3 KEY68074.1 - 4.9e-161 536.5 0.0 6.4e-161 536.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) HPP PF04982.8 KEY68075.1 - 1e-36 125.3 5.4 1e-36 125.3 3.8 1.4 2 0 0 2 2 2 1 HPP family RRM_6 PF14259.1 KEY68076.1 - 0.071 13.1 0.0 0.93 9.5 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Chromo PF00385.19 KEY68077.1 - 1e-07 31.5 0.3 9.3e-07 28.4 0.4 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Pam17 PF08566.5 KEY68078.1 - 2.8e-60 202.9 0.0 3.9e-60 202.4 0.0 1.3 1 1 0 1 1 1 1 Mitochondrial import protein Pam17 BPD_transp_2 PF02653.11 KEY68078.1 - 0.00056 18.9 0.4 0.00084 18.3 0.3 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component MoeZ_MoeB PF05237.8 KEY68079.1 - 5.7e-21 73.9 0.0 1.2e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain ThiF PF00899.16 KEY68079.1 - 5.3e-17 61.9 0.0 1.3e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.15 KEY68079.1 - 4.1e-12 46.4 0.0 6.9e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain SLX9 PF15341.1 KEY68080.1 - 1.3e-35 122.4 0.4 2.2e-35 121.6 0.3 1.4 1 1 0 1 1 1 1 Ribosome biogenesis protein SLX9 Peptidase_C48 PF02902.14 KEY68081.1 - 4.4e-19 68.9 0.0 1.2e-18 67.5 0.0 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain AIG2_2 PF13772.1 KEY68083.1 - 1.5e-06 28.2 0.0 6e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 AIG2-like family DUF3267 PF11667.3 KEY68083.1 - 0.034 14.3 1.3 0.056 13.6 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3267) NAD_Gly3P_dh_N PF01210.18 KEY68084.1 - 5.7e-46 156.0 0.0 9.9e-46 155.3 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 KEY68084.1 - 1.5e-41 141.5 0.3 2.6e-41 140.8 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus COesterase PF00135.23 KEY68085.1 - 2.9e-97 326.6 0.0 4.1e-97 326.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEY68085.1 - 0.00016 21.2 0.0 0.00039 20.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEY68085.1 - 0.11 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEY68086.1 - 1.5e-12 47.4 0.7 4.3e-12 46.0 0.4 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY68086.1 - 3.1e-12 46.8 1.8 3.1e-12 46.8 1.2 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family LIP PF03583.9 KEY68086.1 - 1.4e-10 40.8 1.0 0.00028 20.2 0.5 2.3 2 0 0 2 2 2 2 Secretory lipase Peptidase_S9 PF00326.16 KEY68086.1 - 0.0017 17.5 0.2 0.34 10.0 0.2 2.7 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KEY68086.1 - 0.014 14.9 1.2 0.26 10.8 0.1 2.8 2 1 0 3 3 3 0 alpha/beta hydrolase fold DUF2974 PF11187.3 KEY68086.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DLH PF01738.13 KEY68086.1 - 0.021 14.1 0.2 3 7.0 0.2 2.7 2 1 0 2 2 2 0 Dienelactone hydrolase family hDGE_amylase PF14701.1 KEY68087.1 - 3.7e-175 582.8 0.0 4.9e-175 582.4 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 KEY68087.1 - 3.4e-115 384.7 0.8 4.7e-115 384.2 0.0 1.5 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 KEY68087.1 - 9e-91 303.6 0.0 2.7e-90 302.0 0.0 1.8 2 0 0 2 2 2 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 KEY68087.1 - 2.5e-26 91.3 0.0 6.5e-26 89.9 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 KEY68087.1 - 0.00049 19.5 0.1 0.46 9.8 0.0 2.4 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Trep_Strep PF09605.5 KEY68088.1 - 0.092 12.4 0.2 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Epiglycanin_C PF14654.1 KEY68088.1 - 0.18 11.8 0.1 0.18 11.8 0.1 1.8 1 1 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region UPF0370 PF13980.1 KEY68088.1 - 0.23 11.3 3.2 0.56 10.0 2.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) DUF221 PF02714.10 KEY68090.1 - 9.1e-86 287.6 19.1 1.3e-85 287.0 13.3 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KEY68090.1 - 7.4e-41 139.3 0.5 7.4e-41 139.3 0.4 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KEY68090.1 - 5.4e-21 74.9 0.6 9.2e-21 74.1 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) F-box-like PF12937.2 KEY68091.1 - 0.00035 20.2 0.2 0.00087 18.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like 2-Hacid_dh_C PF02826.14 KEY68092.1 - 8.8e-55 184.5 0.0 1.5e-54 183.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KEY68092.1 - 1.6e-31 108.4 0.0 2.3e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KEY68092.1 - 7.2e-07 29.1 0.0 4.3e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 KEY68092.1 - 0.00017 21.2 0.9 0.067 12.7 0.0 2.2 1 1 1 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.16 KEY68092.1 - 0.0014 18.4 0.3 0.0039 17.0 0.0 1.8 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.1 KEY68092.1 - 0.027 14.7 0.0 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_Gly3P_dh_N PF01210.18 KEY68092.1 - 0.034 13.8 0.0 0.21 11.3 0.0 2.2 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.7 KEY68092.1 - 0.035 13.4 0.0 0.2 10.9 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain CoA_binding_2 PF13380.1 KEY68092.1 - 0.043 13.9 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 CoA binding domain FMO-like PF00743.14 KEY68094.1 - 2.2e-15 55.8 0.0 4.7e-13 48.1 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KEY68094.1 - 5.9e-14 52.6 0.0 9.3e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEY68094.1 - 2.9e-10 40.1 0.1 1e-09 38.3 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KEY68094.1 - 4.9e-09 35.5 0.0 1.6e-08 33.9 0.0 1.7 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KEY68094.1 - 1.7e-07 31.1 0.0 1.2e-06 28.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KEY68094.1 - 4.6e-06 26.6 0.0 6.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEY68094.1 - 0.0018 17.2 0.0 1.9 7.2 0.0 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEY68094.1 - 0.0019 18.5 0.4 2.8 8.3 0.3 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KEY68094.1 - 0.0057 15.7 0.0 0.5 9.3 0.0 2.7 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 KEY68094.1 - 0.0065 15.5 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KEY68094.1 - 0.0078 14.7 0.1 0.013 13.9 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 KEY68094.1 - 0.04 12.9 0.1 0.076 12.0 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_10 PF13460.1 KEY68095.1 - 9.1e-15 55.1 0.0 1.8e-14 54.1 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEY68095.1 - 0.00027 20.4 0.0 0.00039 19.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DHHA1 PF02272.14 KEY68095.1 - 0.06 13.0 0.0 1.9 8.2 0.0 2.6 2 0 0 2 2 2 0 DHHA1 domain 4HBT PF03061.17 KEY68096.1 - 0.0034 17.4 0.0 0.0061 16.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily C2 PF00168.25 KEY68097.1 - 3e-09 36.6 0.0 7.7e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain FKBP_C PF00254.23 KEY68098.1 - 1e-23 83.1 0.0 1.2e-23 82.9 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ThiF PF00899.16 KEY68099.1 - 2e-52 176.6 0.0 2.9e-32 111.3 0.0 2.6 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 KEY68099.1 - 9.3e-41 137.2 1.2 2.7e-27 94.1 0.1 3.4 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 KEY68099.1 - 2e-37 128.1 0.0 4.7e-37 126.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 KEY68099.1 - 9.4e-25 85.7 5.2 8.8e-20 69.8 1.3 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site GST_N_2 PF13409.1 KEY68100.1 - 1.8e-23 82.3 0.1 5.7e-23 80.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEY68100.1 - 2.4e-14 52.9 0.1 5.1e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KEY68100.1 - 2.6e-07 30.7 0.1 0.03 14.5 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KEY68100.1 - 2.3e-05 24.7 0.0 5.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KEY68100.1 - 3.5e-05 23.6 0.0 9e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PDT PF00800.13 KEY68101.1 - 4.9 6.6 7.0 9.8 5.6 4.9 1.4 1 0 0 1 1 1 0 Prephenate dehydratase Sec1 PF00995.18 KEY68102.1 - 1.1e-136 456.8 0.0 1.2e-136 456.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family G-patch PF01585.18 KEY68103.1 - 1.9e-06 27.5 0.1 4.9e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 G-patch domain Fungal_trans PF04082.13 KEY68104.1 - 6.6e-12 44.8 0.0 1.3e-11 43.8 0.0 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY68104.1 - 1.4e-09 37.6 12.3 4.2e-09 36.1 8.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo5 PF09810.4 KEY68105.1 - 3.4e-108 361.6 0.0 4.3e-108 361.3 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 KEY68105.1 - 0.00062 19.2 0.1 0.057 12.7 0.1 2.6 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Glyco_hydro_7 PF00840.15 KEY68107.1 - 2.1e-151 504.1 1.5 2.5e-151 503.9 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DHO_dh PF01180.16 KEY68109.1 - 3e-66 223.3 0.0 4.5e-66 222.8 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 KEY68109.1 - 0.00065 18.6 2.1 0.51 9.1 1.1 2.4 2 1 0 2 2 2 2 FMN-dependent dehydrogenase PcrB PF01884.12 KEY68109.1 - 0.0018 17.5 1.6 0.83 8.8 0.0 2.3 2 0 0 2 2 2 2 PcrB family Mg_trans_NIPA PF05653.9 KEY68110.1 - 4.8e-92 308.1 22.5 6.7e-92 307.6 15.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KEY68110.1 - 1.7e-07 31.4 5.6 1.7e-07 31.4 3.9 3.2 2 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KEY68110.1 - 4.6e-07 29.9 6.5 4.6e-07 29.9 4.5 3.0 3 1 1 4 4 4 2 EamA-like transporter family DUF914 PF06027.7 KEY68110.1 - 0.002 17.0 4.1 0.002 17.0 2.8 1.7 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) TPR_11 PF13414.1 KEY68111.1 - 3.6e-20 71.3 3.4 6.7e-17 60.8 0.1 2.5 1 1 1 2 2 2 2 TPR repeat U-box PF04564.10 KEY68111.1 - 4.3e-20 71.4 0.0 8.8e-20 70.4 0.0 1.6 1 0 0 1 1 1 1 U-box domain TPR_2 PF07719.12 KEY68111.1 - 3.5e-14 51.5 3.0 0.00099 18.8 0.6 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEY68111.1 - 1.5e-13 49.7 4.0 0.0031 17.0 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEY68111.1 - 5.3e-08 33.3 3.5 0.00027 21.5 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEY68111.1 - 1e-07 31.5 0.6 0.0064 16.5 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEY68111.1 - 1.1e-07 31.8 0.3 0.12 13.1 0.0 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEY68111.1 - 2e-06 27.6 1.5 0.0014 18.5 0.4 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEY68111.1 - 1e-05 24.9 3.2 0.11 12.3 0.3 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEY68111.1 - 1.3e-05 25.3 0.1 0.0057 16.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KEY68111.1 - 3.5e-05 23.8 0.8 6.3e-05 23.0 0.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KEY68111.1 - 0.00094 18.9 1.4 0.0019 18.0 0.0 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEY68111.1 - 0.0051 17.1 0.8 1.7 9.2 0.3 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEY68111.1 - 0.055 13.2 5.9 17 5.5 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat DIE2_ALG10 PF04922.7 KEY68113.1 - 7e-77 259.0 17.3 5.4e-59 200.1 0.4 3.3 3 0 0 3 3 3 3 DIE2/ALG10 family QCR10 PF09796.4 KEY68113.1 - 1.2e-17 63.3 0.2 3.3e-17 61.9 0.0 1.9 2 0 0 2 2 2 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Med4 PF10018.4 KEY68114.1 - 1.4e-41 141.9 15.0 4e-41 140.4 10.4 1.8 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 MAP7 PF05672.6 KEY68114.1 - 0.039 13.3 24.5 0.084 12.2 17.0 1.5 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family EMP70 PF02990.11 KEY68115.1 - 8.3e-187 621.7 4.9 1e-186 621.4 3.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 NfeD PF01957.13 KEY68115.1 - 0.0082 16.2 0.0 0.0082 16.2 0.0 4.1 2 2 3 5 5 5 1 NfeD-like C-terminal, partner-binding Sas10_Utp3 PF04000.10 KEY68116.1 - 7.5e-16 58.1 2.2 1.4e-15 57.2 1.5 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF3069 PF11269.3 KEY68116.1 - 0.0031 17.6 0.1 0.0069 16.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3069) CDV3 PF15359.1 KEY68116.1 - 1.5 8.8 9.9 0.083 12.9 2.8 1.9 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Sin_N PF04801.8 KEY68117.1 - 5.7e-24 84.7 0.0 7.5e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region PAT1 PF09770.4 KEY68118.1 - 2.8e-228 760.1 17.7 5.4e-228 759.2 12.2 1.4 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.11 KEY68119.1 - 7e-142 472.2 5.5 8.4e-142 471.9 3.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CDI PF02234.14 KEY68119.1 - 0.0065 16.2 0.6 0.02 14.7 0.4 1.8 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor Ribosom_S12_S23 PF00164.20 KEY68120.1 - 4.6e-41 139.0 1.1 5.7e-41 138.7 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Acyl-CoA_dh_1 PF00441.19 KEY68121.1 - 8.3e-42 142.8 4.6 1.2e-41 142.3 3.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KEY68121.1 - 1.4e-29 102.9 1.1 5.8e-29 100.9 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KEY68121.1 - 3.6e-17 62.8 1.5 6.1e-17 62.1 1.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KEY68121.1 - 7e-17 60.6 0.1 1.3e-16 59.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.3 KEY68121.1 - 0.0016 17.8 0.1 0.008 15.6 0.0 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF3184 PF11380.3 KEY68121.1 - 0.12 10.2 0.1 0.18 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3184) HR1 PF02185.11 KEY68122.1 - 1e-26 92.4 9.1 3.8e-14 52.1 0.2 2.4 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 KEY68122.1 - 3.2e-17 61.9 36.6 2.4e-11 43.1 8.4 2.2 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KEY68122.1 - 0.0059 17.1 2.2 0.023 15.2 1.5 2.2 1 1 0 1 1 1 1 Protein kinase C terminal domain She9_MDM33 PF05546.6 KEY68123.1 - 3.9e-78 261.7 4.8 5.6e-78 261.2 3.3 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family BCAS2 PF05700.6 KEY68123.1 - 0.022 14.2 2.1 0.034 13.5 1.4 1.4 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF4398 PF14346.1 KEY68123.1 - 0.036 14.1 1.3 0.036 14.1 0.9 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4398) DivIVA PF05103.8 KEY68123.1 - 0.5 10.4 6.3 2 8.4 0.5 2.4 2 0 0 2 2 2 0 DivIVA protein HAD PF12710.2 KEY68124.1 - 5.4e-15 56.0 0.0 7.5e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 KEY68124.1 - 9.2e-06 25.1 0.0 3.1e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 KEY68124.1 - 1e-05 25.8 0.0 3.8e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KEY68124.1 - 0.0083 15.3 0.0 0.13 11.3 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase PF00702.21 KEY68124.1 - 0.12 12.7 0.3 2.4 8.5 0.0 2.4 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase eIF-1a PF01176.14 KEY68125.1 - 3e-15 55.3 0.0 4.5e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.8 KEY68126.1 - 2e-135 451.7 15.4 2.5e-135 451.4 10.7 1.1 1 0 0 1 1 1 1 ALG3 protein Thioredoxin PF00085.15 KEY68126.1 - 1e-23 83.0 0.0 1.7e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DAO PF01266.19 KEY68126.1 - 2.5e-20 72.6 0.0 5.8e-20 71.4 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thioredoxin_8 PF13905.1 KEY68126.1 - 0.0026 17.8 0.0 0.017 15.1 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KEY68126.1 - 0.0046 17.1 0.2 0.027 14.6 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 KEY68126.1 - 0.039 13.5 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Nuf2 PF03800.9 KEY68128.1 - 5e-45 153.0 0.1 5e-45 153.0 0.1 2.7 3 0 0 3 3 3 1 Nuf2 family Caldesmon PF02029.10 KEY68128.1 - 6.9 4.9 42.8 2.9 6.2 13.9 2.3 2 0 0 2 2 2 0 Caldesmon Adaptin_N PF01602.15 KEY68130.1 - 1e-106 357.3 0.0 1.3e-106 357.0 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KEY68130.1 - 7.8e-15 54.9 1.3 9.8e-06 25.7 0.0 4.7 3 1 0 4 4 4 3 HEAT repeats HEAT PF02985.17 KEY68130.1 - 9e-10 37.8 0.9 0.033 14.2 0.0 5.5 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 KEY68130.1 - 7.4e-06 26.2 2.8 0.011 16.1 0.0 4.9 5 0 0 5 5 5 1 HEAT-like repeat Cohesin_HEAT PF12765.2 KEY68130.1 - 0.0002 21.2 0.5 0.18 11.8 0.0 3.9 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 KEY68130.1 - 0.0018 18.1 0.0 0.25 11.1 0.0 2.8 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KEY68130.1 - 0.0022 17.3 0.2 3.1 7.0 0.0 3.3 2 1 1 3 3 3 1 CLASP N terminal CRISPR_Cse2 PF09485.5 KEY68130.1 - 0.023 14.7 3.0 0.11 12.4 0.5 2.9 3 0 0 3 3 3 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Daxx PF03344.10 KEY68130.1 - 1.2 7.5 25.4 2.1 6.7 17.6 1.4 1 0 0 1 1 1 0 Daxx Family Sigma70_ner PF04546.8 KEY68130.1 - 1.8 8.1 20.1 4.2 6.9 14.0 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 KEY68130.1 - 7.6 5.6 15.8 14 4.8 10.9 1.4 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.8 KEY68130.1 - 9 6.0 22.1 2.4 7.9 13.2 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RTA1 PF04479.8 KEY68131.1 - 3e-39 134.8 1.4 4.2e-39 134.3 0.9 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF4131 PF13567.1 KEY68131.1 - 3.5 7.0 9.5 4.5 6.6 0.1 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) NAD_binding_2 PF03446.10 KEY68132.1 - 1.9e-36 125.3 0.4 2.9e-36 124.7 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KEY68132.1 - 7.4e-31 106.7 0.0 1.4e-30 105.8 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KEY68132.1 - 6e-08 33.0 0.0 3.5e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.10 KEY68132.1 - 5.2e-06 25.4 0.0 8.4e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.17 KEY68132.1 - 8.6e-05 23.0 0.0 0.00048 20.6 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_Gly3P_dh_N PF01210.18 KEY68132.1 - 9.6e-05 22.1 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ldh_1_N PF00056.18 KEY68132.1 - 0.0027 17.5 0.0 0.0071 16.1 0.0 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain TrkA_N PF02254.13 KEY68132.1 - 0.01 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Semialdhyde_dh PF01118.19 KEY68132.1 - 0.016 15.4 0.0 0.042 14.1 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KEY68132.1 - 0.097 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KEY68132.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase KilA-N PF04383.8 KEY68133.1 - 0.00082 18.9 0.0 0.051 13.2 0.0 2.5 1 1 0 1 1 1 1 KilA-N domain DIOX_N PF14226.1 KEY68133.1 - 0.056 13.9 1.0 0.11 13.0 0.7 1.5 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal DUF2146 PF10220.4 KEY68133.1 - 0.83 7.5 5.2 1.4 6.7 3.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) ATP-synt_G PF04718.10 KEY68133.1 - 1.1 10.0 6.0 3.6 8.2 0.2 2.6 2 1 0 2 2 2 0 Mitochondrial ATP synthase g subunit DUF4551 PF15087.1 KEY68133.1 - 8 4.6 13.7 4.6 5.4 8.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4551) Sugar_tr PF00083.19 KEY68136.1 - 2e-83 280.4 20.0 2.3e-83 280.2 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY68136.1 - 4.3e-38 130.9 41.5 1.1e-32 113.2 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KEY68136.1 - 2.4e-07 29.3 1.2 2.4e-07 29.3 0.8 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KEY68136.1 - 2.3e-06 26.2 20.7 5e-06 25.1 1.8 2.7 2 2 0 2 2 2 2 MFS/sugar transport protein Phage_Coat_A PF05357.8 KEY68137.1 - 0.078 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Phage Coat Protein A Adaptin_N PF01602.15 KEY68139.1 - 1.9e-114 382.9 0.4 2.4e-114 382.5 0.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KEY68139.1 - 2.8e-59 199.2 3.1 6.3e-59 198.1 2.1 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KEY68139.1 - 1.7e-14 53.8 1.9 0.00011 22.3 0.0 6.0 2 1 3 5 5 5 3 HEAT repeats HEAT_PBS PF03130.11 KEY68139.1 - 0.022 15.2 0.0 43 4.9 0.0 4.5 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat DUF3730 PF12530.3 KEY68139.1 - 0.079 12.8 2.1 0.46 10.3 0.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3730) HEAT PF02985.17 KEY68139.1 - 0.21 11.7 6.9 1.5 9.1 0.2 4.8 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.1 KEY68139.1 - 7.3 7.2 6.6 3.1 8.4 0.4 3.3 2 1 0 2 2 2 0 HEAT-like repeat ATP12 PF07542.6 KEY68140.1 - 1.8e-28 98.9 0.1 3e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein UnbV_ASPIC PF07593.7 KEY68140.1 - 0.02 14.5 0.2 0.048 13.3 0.2 1.6 1 0 0 1 1 1 0 ASPIC and UnbV zf-HIT PF04438.11 KEY68141.1 - 0.21 11.2 5.4 0.052 13.2 1.1 2.0 2 0 0 2 2 2 0 HIT zinc finger Asp PF00026.18 KEY68143.1 - 1e-51 176.0 0.0 1.5e-51 175.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEY68143.1 - 1.7e-05 24.8 2.4 2.3e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KEY68143.1 - 0.00062 20.2 1.4 9.3 6.8 0.0 4.1 4 0 0 4 4 4 2 Aspartyl protease AMP-binding PF00501.23 KEY68144.1 - 2.5e-74 250.1 0.0 3.1e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEY68144.1 - 9e-13 48.9 1.9 2.3e-12 47.6 0.4 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF2577 PF10844.3 KEY68144.1 - 0.066 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2577) CFEM PF05730.6 KEY68145.1 - 0.00062 19.5 1.6 0.00062 19.5 1.1 2.6 2 0 0 2 2 2 1 CFEM domain Ank_5 PF13857.1 KEY68147.1 - 0.00015 21.8 0.4 0.00035 20.7 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) MT0933_antitox PF14013.1 KEY68148.1 - 0.0078 16.2 6.0 0.0078 16.2 4.2 1.7 2 0 0 2 2 2 1 MT0933-like antitoxin protein DUF1213 PF06740.7 KEY68148.1 - 0.13 12.4 0.1 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1213) NAD_binding_8 PF13450.1 KEY68149.1 - 1.4e-14 53.8 0.1 3.4e-14 52.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEY68149.1 - 2.8e-13 49.5 0.0 5.8e-12 45.1 0.0 2.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KEY68149.1 - 4.7e-11 42.4 0.3 2.2e-10 40.2 0.0 2.2 2 1 1 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 KEY68149.1 - 3.3e-06 26.2 3.1 1.6e-05 23.9 2.6 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KEY68149.1 - 1.3e-05 23.8 0.1 0.0013 17.3 0.6 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 KEY68149.1 - 1.7e-05 24.7 0.0 3.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEY68149.1 - 5.8e-05 22.3 0.0 0.00016 20.9 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEY68149.1 - 0.00013 22.0 0.1 0.00074 19.6 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEY68149.1 - 0.00044 19.4 0.7 0.00084 18.4 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KEY68149.1 - 0.00074 19.8 2.1 0.004 17.5 1.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEY68149.1 - 0.0014 17.8 0.4 0.0023 17.0 0.3 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 KEY68149.1 - 0.0029 16.6 0.5 0.0056 15.6 0.4 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KEY68149.1 - 0.0052 16.5 0.5 0.017 14.9 0.3 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding ApbA PF02558.11 KEY68149.1 - 0.0091 15.4 0.6 0.017 14.6 0.4 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Strep_67kDa_ant PF06100.6 KEY68149.1 - 0.069 11.5 0.2 8.3 4.6 0.0 2.1 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family GIDA PF01134.17 KEY68149.1 - 0.076 11.8 2.1 0.18 10.6 1.2 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 KEY68149.1 - 0.094 12.3 0.9 0.15 11.6 0.7 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 KEY68149.1 - 0.13 12.0 0.2 0.27 11.0 0.2 1.5 1 0 0 1 1 1 0 ThiF family F420_oxidored PF03807.12 KEY68149.1 - 0.15 12.5 0.6 0.54 10.7 0.4 2.0 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent XdhC_C PF13478.1 KEY68149.1 - 0.15 12.3 0.0 0.6 10.4 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain TrkA_N PF02254.13 KEY68149.1 - 0.15 12.0 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain GDI PF00996.13 KEY68149.1 - 0.2 9.9 0.1 5.5 5.1 0.0 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor SQS_PSY PF00494.14 KEY68150.1 - 3.1e-65 220.1 0.4 4.7e-65 219.5 0.3 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase Ank_2 PF12796.2 KEY68151.1 - 1.4e-66 220.8 21.1 1.4e-16 60.5 0.5 4.9 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KEY68151.1 - 1.7e-53 175.8 24.3 9.3e-07 28.3 0.0 10.5 10 0 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.1 KEY68151.1 - 4.8e-38 125.3 1.7 0.0015 18.5 0.0 10.6 10 1 1 11 11 11 7 Ankyrin repeat Ank_4 PF13637.1 KEY68151.1 - 1.3e-37 127.5 3.3 3e-09 37.1 0.0 6.6 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY68151.1 - 3.6e-36 122.3 17.0 9.7e-08 32.0 0.2 9.3 4 3 6 10 10 10 7 Ankyrin repeats (many copies) LTXXQ PF07813.7 KEY68152.1 - 0.012 16.0 1.3 2.9 8.4 0.0 2.5 2 0 0 2 2 2 0 LTXXQ motif family protein FAD_binding_7 PF03441.9 KEY68153.1 - 2.3e-54 184.4 0.0 3.2e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KEY68153.1 - 9.7e-23 80.7 0.0 1.7e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase MmgE_PrpD PF03972.9 KEY68154.1 - 1.7e-147 491.2 0.1 2.6e-147 490.5 0.0 1.3 2 0 0 2 2 2 1 MmgE/PrpD family SH3_1 PF00018.23 KEY68155.1 - 2.4e-12 46.0 0.1 3.8e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KEY68155.1 - 8.8e-10 38.0 0.1 1.5e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KEY68155.1 - 1e-08 34.5 0.0 1.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain CMS1 PF14617.1 KEY68156.1 - 2.2e-81 272.6 6.0 1.3e-79 266.8 4.2 2.0 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 KEY68156.1 - 1.1e-07 31.5 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase CFEM PF05730.6 KEY68157.1 - 0.0036 17.1 3.8 0.0036 17.1 2.6 1.7 2 0 0 2 2 2 1 CFEM domain Ras PF00071.17 KEY68158.1 - 2.5e-49 166.7 0.0 1.3e-47 161.1 0.0 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KEY68158.1 - 2.9e-17 63.2 0.0 4.5e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEY68158.1 - 2.4e-05 23.6 0.0 0.00058 19.1 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEY68158.1 - 0.00053 19.4 0.0 0.00077 18.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RRM_1 PF00076.17 KEY68159.1 - 1.3e-09 37.5 0.0 3.3e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY68159.1 - 8.4e-09 35.2 0.0 2.5e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TFIIF_alpha PF05793.7 KEY68159.1 - 0.00023 19.7 54.1 0.00023 19.7 37.5 2.1 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AAA_23 PF13476.1 KEY68159.1 - 0.55 10.5 30.2 0.1 12.9 13.4 2.2 2 0 0 2 2 2 0 AAA domain Pkinase_Tyr PF07714.12 KEY68160.1 - 8.1e-16 57.8 0.0 1.5e-15 57.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KEY68160.1 - 2.3e-11 43.3 0.0 9.5e-11 41.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KEY68160.1 - 0.0046 16.0 0.0 0.0074 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_61 PF03443.9 KEY68162.1 - 2.3e-73 246.6 0.2 2.8e-73 246.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Metallophos PF00149.23 KEY68163.1 - 1.5e-15 57.1 0.1 2.8e-15 56.2 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEY68163.1 - 1.1e-05 25.3 0.2 2e-05 24.5 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SAP PF02037.22 KEY68164.1 - 1.6e-14 52.9 0.2 2.8e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 KEY68164.1 - 0.0011 18.4 0.3 0.0025 17.3 0.2 1.6 1 1 0 1 1 1 1 HeH/LEM domain U79_P34 PF03064.11 KEY68164.1 - 1.7 8.1 8.6 2.7 7.4 6.0 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Presenilin PF01080.12 KEY68164.1 - 2.3 6.9 3.2 3.2 6.4 2.2 1.1 1 0 0 1 1 1 0 Presenilin Methyltransf_11 PF08241.7 KEY68166.1 - 0.013 15.9 0.0 0.034 14.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KEY68166.1 - 0.6 9.1 0.0 1 8.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Clr5 PF14420.1 KEY68168.1 - 4.3e-21 74.5 0.6 2.9e-20 71.9 0.5 2.3 2 0 0 2 2 2 1 Clr5 domain BetaGal_dom4_5 PF13364.1 KEY68168.1 - 0.071 13.3 0.2 0.33 11.2 0.0 2.1 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain Pkinase PF00069.20 KEY68169.1 - 4.5e-49 166.9 0.0 9.9e-49 165.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY68169.1 - 2.3e-27 95.6 0.0 3.8e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY68169.1 - 0.059 12.3 0.0 0.62 8.9 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Clr5 PF14420.1 KEY68170.1 - 1e-19 70.1 0.8 2.6e-19 68.8 0.6 1.8 1 0 0 1 1 1 1 Clr5 domain TPR_11 PF13414.1 KEY68170.1 - 0.088 12.4 0.2 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 KEY68170.1 - 0.12 12.3 0.0 0.5 10.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.2 KEY68172.1 - 1.9e-06 28.1 0.0 7.8e-06 26.1 0.0 2.1 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.25 KEY68172.1 - 0.0014 18.3 0.0 0.19 11.6 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 KEY68172.1 - 0.0045 17.4 0.0 0.024 15.1 0.0 2.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY68172.1 - 0.012 15.7 0.0 7.9 7.0 0.0 3.8 3 0 0 3 3 3 0 Ankyrin repeat zf-C2H2 PF00096.21 KEY68172.1 - 1 9.8 8.9 0.22 11.9 2.7 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type DNA_primase_lrg PF04104.9 KEY68173.1 - 6e-82 274.8 0.0 9.5e-82 274.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Mut7-C PF01927.11 KEY68174.1 - 0.023 14.6 0.2 0.024 14.5 0.1 1.1 1 0 0 1 1 1 0 Mut7-C RNAse domain DUF3268 PF11672.3 KEY68174.1 - 0.036 14.1 0.7 0.053 13.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3268) zf-FPG_IleRS PF06827.9 KEY68174.1 - 0.043 13.4 1.2 0.64 9.7 0.0 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DUF1660 PF07874.6 KEY68174.1 - 0.14 12.4 2.7 1.9 8.8 0.1 2.2 1 1 1 2 2 2 0 Prophage protein (DUF1660) Yippee-Mis18 PF03226.9 KEY68174.1 - 0.21 11.6 1.5 12 6.0 0.1 2.1 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-RING_3 PF14369.1 KEY68174.1 - 0.8 9.7 3.3 8.7 6.4 0.1 2.4 2 0 0 2 2 2 0 zinc-finger DNA_RNApol_7kD PF03604.8 KEY68174.1 - 7 6.2 7.1 2.1 7.9 0.2 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Thioredoxin PF00085.15 KEY68175.1 - 8.9e-23 79.9 0.0 1e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KEY68175.1 - 1.8e-06 27.9 0.0 3e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KEY68175.1 - 4.5e-06 26.8 0.1 8.6e-05 22.7 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KEY68175.1 - 0.00085 19.3 0.1 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 KEY68175.1 - 0.0027 17.3 0.1 0.0059 16.2 0.1 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 KEY68175.1 - 0.009 15.5 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 KEY68175.1 - 0.0098 15.4 0.2 0.021 14.3 0.1 1.5 1 1 1 2 2 2 1 Redoxin HyaE PF07449.6 KEY68175.1 - 0.016 15.1 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Phosducin PF02114.11 KEY68175.1 - 0.049 12.3 0.0 0.057 12.1 0.0 1.0 1 0 0 1 1 1 0 Phosducin GHMP_kinases_C PF08544.8 KEY68176.1 - 0.0014 18.8 0.6 0.093 12.9 0.2 2.6 1 1 1 2 2 2 2 GHMP kinases C terminal Baculo_PEP_C PF04513.7 KEY68176.1 - 0.04 13.7 7.2 0.18 11.6 0.8 2.6 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PuR_N PF09182.5 KEY68176.1 - 0.14 11.7 0.8 0.44 10.1 0.5 1.8 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal KAR9 PF08580.5 KEY68176.1 - 0.14 10.3 0.1 0.16 10.2 0.0 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 WXG100 PF06013.7 KEY68176.1 - 0.16 11.9 0.7 1.9 8.5 0.2 2.6 1 1 1 2 2 2 0 Proteins of 100 residues with WXG FBPase PF00316.15 KEY68177.1 - 4.5e-53 180.1 0.0 6.1e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase GST_N PF02798.15 KEY68179.1 - 1.8e-15 56.8 0.0 3.8e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KEY68179.1 - 1.1e-13 51.2 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEY68179.1 - 1.1e-11 44.5 0.0 3.2e-11 43.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEY68179.1 - 9.8e-10 38.1 0.0 1.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KEY68179.1 - 1.3e-08 34.7 0.0 2.2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEY68179.1 - 5.8e-07 29.9 0.1 1e-06 29.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 KEY68179.1 - 0.082 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin ATPgrasp_Ter PF15632.1 KEY68179.1 - 0.14 10.8 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Metallophos PF00149.23 KEY68181.1 - 4.2e-12 45.8 0.1 9.5e-12 44.7 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEY68181.1 - 5e-06 26.4 0.0 1.5e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AbfB PF05270.8 KEY68181.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B (ABFB) DnaJ PF00226.26 KEY68182.1 - 6.2e-22 77.1 2.0 3.6e-21 74.6 1.4 2.5 1 0 0 1 1 1 1 DnaJ domain GST_C PF00043.20 KEY68183.1 - 2.3e-13 49.9 0.0 3.1e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KEY68183.1 - 5.6e-12 45.7 0.0 9.9e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KEY68183.1 - 9.1e-12 44.9 0.0 2e-11 43.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEY68183.1 - 4e-08 33.1 0.0 8.4e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEY68183.1 - 2.9e-06 27.0 0.0 7e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEY68183.1 - 0.0087 16.5 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AMP-binding PF00501.23 KEY68184.1 - 7.3e-66 222.2 0.0 1.2e-65 221.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KEY68184.1 - 2.9e-64 216.3 0.0 4.3e-64 215.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KEY68184.1 - 4.2e-13 49.2 0.0 7.8e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KEY68184.1 - 9.2e-10 38.6 0.0 2.4e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KEY68184.1 - 1.4e-08 35.5 0.0 3.5e-07 31.0 0.0 2.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 KEY68184.1 - 1.1e-07 30.8 0.0 2.2e-07 29.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KEY68184.1 - 0.0016 17.4 0.0 0.041 12.7 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KEY68184.1 - 0.064 12.1 0.1 1.4 7.7 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain Peptidase_M28 PF04389.12 KEY68187.1 - 4.3e-31 108.0 0.0 7.2e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KEY68187.1 - 4.9e-15 55.0 0.4 1.1e-14 53.9 0.3 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 KEY68187.1 - 1.6e-05 24.4 0.1 3.2e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 HATPase_c_3 PF13589.1 KEY68188.1 - 0.00043 19.9 0.0 0.00092 18.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribonuclease PF00545.15 KEY68189.1 - 2.2e-05 24.4 0.0 0.00014 21.8 0.0 2.1 2 1 0 2 2 2 1 ribonuclease Fimbrial_PilY2 PF14481.1 KEY68189.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 DUF3632 PF12311.3 KEY68190.1 - 2.9e-17 63.0 0.0 4.6e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) HET PF06985.6 KEY68191.1 - 5.6e-21 75.1 0.1 9.2e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1220 PF06758.8 KEY68191.1 - 0.059 13.1 0.1 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 Repeat of unknown function (DUF1220) Ank_2 PF12796.2 KEY68192.1 - 8.6e-16 58.0 0.2 7.4e-11 42.2 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEY68192.1 - 2.4e-15 56.1 0.3 7.6e-08 32.3 0.0 4.8 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY68192.1 - 1.6e-12 46.3 0.0 0.048 13.9 0.0 6.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 KEY68192.1 - 2.3e-11 43.8 0.1 4e-07 30.3 0.0 4.4 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 KEY68192.1 - 2e-08 33.6 0.2 0.15 11.9 0.0 5.5 5 0 0 5 5 5 1 Ankyrin repeat NACHT PF05729.7 KEY68192.1 - 2e-07 30.8 0.0 1.6e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KEY68192.1 - 7.9e-06 25.9 0.0 3.2e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEY68192.1 - 8.4e-06 25.9 0.1 0.0002 21.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 KEY68192.1 - 0.0036 17.4 0.0 0.59 10.3 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Kinesin PF00225.18 KEY68192.1 - 0.016 13.9 0.0 0.03 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinesin motor domain AAA PF00004.24 KEY68192.1 - 0.04 14.1 0.0 0.37 10.9 0.0 2.6 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 KEY68192.1 - 0.074 12.0 0.0 9.7 5.0 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain AAA_14 PF13173.1 KEY68192.1 - 0.082 12.8 0.0 2.5 8.0 0.0 2.5 1 1 0 1 1 1 0 AAA domain Abhydrolase_3 PF07859.8 KEY68193.1 - 9.2e-13 48.2 0.1 1.4e-12 47.6 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_11 PF08241.7 KEY68193.1 - 7.8e-08 32.7 0.0 1.8e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY68193.1 - 2.4e-07 30.4 0.0 6.5e-07 29.0 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY68193.1 - 2.6e-05 24.7 0.0 4.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY68193.1 - 0.00043 20.3 0.0 0.0015 18.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY68193.1 - 0.0046 16.6 0.0 0.046 13.4 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY68193.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HET PF06985.6 KEY68194.1 - 1.2e-30 106.5 0.0 4.1e-30 104.7 0.0 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) SnoaL PF07366.7 KEY68195.1 - 2e-30 104.9 0.0 2.8e-17 62.4 0.0 2.1 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KEY68195.1 - 5.3e-11 42.8 0.0 3.2e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 SnoaL-like domain PNP_UDP_1 PF01048.15 KEY68196.1 - 1.3e-14 53.7 0.1 3.1e-14 52.5 0.1 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily DNA_binding_1 PF01035.15 KEY68197.1 - 6.4e-18 64.2 1.0 7.1e-17 60.9 0.7 2.0 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Kinesin PF00225.18 KEY68198.1 - 2.8e-93 312.2 0.0 2.8e-93 312.2 0.0 3.0 3 0 0 3 3 3 1 Kinesin motor domain ERCC4 PF02732.10 KEY68200.1 - 5.5e-17 61.8 0.2 9.8e-17 61.0 0.1 1.4 1 0 0 1 1 1 1 ERCC4 domain Ycf1 PF05758.7 KEY68200.1 - 0.0055 14.4 3.7 0.0083 13.9 2.5 1.1 1 0 0 1 1 1 1 Ycf1 Adeno_terminal PF02459.10 KEY68200.1 - 0.34 9.0 8.3 0.86 7.6 5.7 1.6 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Peptidase_S49_N PF08496.5 KEY68200.1 - 0.37 10.5 6.4 0.76 9.5 4.4 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PNP_UDP_1 PF01048.15 KEY68204.1 - 8.8e-15 54.3 0.0 1.8e-14 53.2 0.0 1.4 1 1 0 1 1 1 1 Phosphorylase superfamily Zn_clus PF00172.13 KEY68205.1 - 0.003 17.4 1.6 0.0053 16.6 1.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3425 PF11905.3 KEY68207.1 - 4.6e-15 55.7 2.2 7.3e-14 51.8 1.5 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KEY68207.1 - 5.6 6.9 10.5 9.3 6.2 7.3 1.2 1 0 0 1 1 1 0 bZIP transcription factor NmrA PF05368.8 KEY68208.1 - 3.6e-34 118.0 0.0 8.3e-34 116.8 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY68208.1 - 9.8e-12 45.2 0.0 1.4e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KEY68208.1 - 0.00061 19.7 1.1 0.0043 16.9 0.5 2.3 2 1 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KEY68208.1 - 0.0019 16.9 0.0 0.0025 16.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KEY68208.1 - 0.0051 17.1 0.0 0.013 15.7 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 KEY68208.1 - 0.006 16.0 0.0 0.0097 15.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 KEY68208.1 - 0.0089 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 KEY68208.1 - 0.062 12.9 0.0 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 KR domain 4HBT_3 PF13622.1 KEY68209.1 - 1.6e-43 149.2 7.9 2e-43 148.9 5.5 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily p450 PF00067.17 KEY68210.1 - 3.5e-28 98.3 0.0 7e-28 97.3 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 HOK_GEF PF01848.11 KEY68211.1 - 0.0016 17.7 0.3 0.0032 16.7 0.2 1.4 1 0 0 1 1 1 1 Hok/gef family EphA2_TM PF14575.1 KEY68211.1 - 0.051 13.9 0.0 0.13 12.7 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3 PF06040.6 KEY68211.1 - 0.075 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 protein Beta-APP PF03494.8 KEY68211.1 - 0.16 11.4 4.9 0.27 10.7 3.4 1.3 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) CAP59_mtransfer PF11735.3 KEY68212.1 - 1.1e-59 201.6 0.0 1.5e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 CorA PF01544.13 KEY68213.1 - 3.2e-06 26.3 0.2 1.1e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein ADH_N PF08240.7 KEY68214.1 - 6.4e-25 87.0 1.5 1.4e-24 85.9 1.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 KEY68214.1 - 3.9e-08 32.7 0.6 3.9e-08 32.7 0.4 2.8 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 KEY68214.1 - 1.2e-07 31.3 0.1 0.00084 18.8 0.0 2.6 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 KEY68214.1 - 0.0054 16.6 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lipase_3 PF01764.20 KEY68215.1 - 1e-17 64.0 0.0 1.8e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KEY68215.1 - 0.00019 21.3 0.0 0.00032 20.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY68215.1 - 0.0015 18.3 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KEY68215.1 - 0.0017 17.9 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF900 PF05990.7 KEY68215.1 - 0.0049 16.2 0.0 0.008 15.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.9 KEY68215.1 - 0.0076 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2974 PF11187.3 KEY68215.1 - 0.051 12.9 0.0 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Rft-1 PF04506.8 KEY68216.1 - 4.2e-85 286.1 10.9 8.1e-84 281.9 7.5 2.2 1 1 0 1 1 1 1 Rft protein Polysacc_synt PF01943.12 KEY68216.1 - 1.2e-08 34.5 13.2 1.2e-08 34.5 9.2 2.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DEAD PF00270.24 KEY68217.1 - 6.4e-49 165.6 0.0 3.7e-47 159.9 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY68217.1 - 2.1e-28 97.9 0.0 2.6e-27 94.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KEY68217.1 - 0.002 16.5 0.0 0.002 16.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) MIP-T3 PF10243.4 KEY68217.1 - 5.9 5.2 49.8 8.8 4.6 34.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 HORMA PF02301.13 KEY68218.1 - 8.1e-45 152.8 0.0 1.1e-44 152.4 0.0 1.2 1 0 0 1 1 1 1 HORMA domain Mucin PF01456.12 KEY68218.1 - 0.58 9.9 7.3 0.1 12.3 0.5 2.3 2 1 0 2 2 2 0 Mucin-like glycoprotein UCH PF00443.24 KEY68219.1 - 1.7e-44 151.9 0.0 2.7e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 KEY68219.1 - 2.6e-22 78.0 0.2 1e-10 41.1 0.0 2.8 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.14 KEY68219.1 - 5.9e-20 71.1 12.3 1.1e-18 67.1 1.1 3.0 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KEY68219.1 - 2.1e-18 66.8 0.0 9.5e-09 35.1 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase NifU_N PF01592.11 KEY68220.1 - 8.4e-52 174.4 0.0 1.2e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain RPE65 PF03055.10 KEY68221.1 - 8.3e-118 393.9 0.0 1.1e-117 393.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Pkinase PF00069.20 KEY68222.1 - 4.6e-15 55.4 0.0 9e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY68222.1 - 1.6e-08 33.9 0.0 8.6e-06 25.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Glyco_hydro_3 PF00933.16 KEY68225.1 - 3.2e-74 249.5 0.0 4.8e-74 249.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY68225.1 - 1.5e-67 227.4 0.0 4.2e-67 225.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEY68225.1 - 8.3e-25 86.5 0.1 4.5e-24 84.1 0.1 2.3 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 KEY68225.1 - 6e-15 55.1 0.1 9.5e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 PA14 domain FTA4 PF13093.1 KEY68226.1 - 1.5e-49 168.3 0.0 1.8e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Nup54 PF13874.1 KEY68226.1 - 0.15 11.7 1.1 0.51 10.0 0.7 1.8 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Glyco_hydro_31 PF01055.21 KEY68227.1 - 1e-171 571.6 5.1 1.3e-171 571.3 3.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KEY68227.1 - 7e-12 45.0 0.6 7e-12 45.0 0.4 2.8 3 0 0 3 3 3 1 Galactose mutarotase-like zf-C2H2_4 PF13894.1 KEY68228.1 - 2.4e-08 33.7 17.9 0.021 15.1 0.2 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY68228.1 - 0.00021 21.4 15.6 0.17 12.3 1.4 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-TRAF PF02176.13 KEY68228.1 - 0.041 14.2 0.7 0.041 14.2 0.5 2.4 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_jaz PF12171.3 KEY68228.1 - 1.7 8.8 6.2 8 6.7 0.4 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Patatin PF01734.17 KEY68229.1 - 1.3e-24 87.2 0.0 3.1e-24 86.0 0.0 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase Fungal_trans_2 PF11951.3 KEY68230.1 - 1.8e-06 26.8 0.1 3.6e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GFO_IDH_MocA PF01408.17 KEY68231.1 - 1.7e-17 64.0 0.0 3.4e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Saccharop_dh PF03435.13 KEY68231.1 - 0.0017 17.3 0.1 0.011 14.7 0.0 2.2 2 1 0 2 2 2 1 Saccharopine dehydrogenase GFO_IDH_MocA_C PF02894.12 KEY68231.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain 4HBT PF03061.17 KEY68232.1 - 9.9e-08 32.0 0.0 1.3e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 KEY68232.1 - 1.5e-05 25.4 0.0 1.8e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 KEY68232.1 - 0.00023 20.1 0.7 0.00035 19.6 0.5 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase PseudoU_synth_2 PF00849.17 KEY68233.1 - 5.6e-30 104.3 0.0 1e-29 103.4 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 KEY68233.1 - 0.015 14.6 0.3 0.034 13.5 0.0 1.7 2 0 0 2 2 2 0 S4 domain Peptidase_U32 PF01136.14 KEY68233.1 - 0.16 10.8 0.2 14 4.4 0.0 2.2 2 0 0 2 2 2 0 Peptidase family U32 bZIP_1 PF00170.16 KEY68234.1 - 0.0022 17.9 13.3 0.0078 16.1 9.2 1.8 1 1 1 2 2 2 1 bZIP transcription factor Mitofilin PF09731.4 KEY68234.1 - 0.097 11.3 6.3 0.14 10.7 4.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein IncA PF04156.9 KEY68234.1 - 1.2 8.7 5.7 1.7 8.1 4.0 1.2 1 0 0 1 1 1 0 IncA protein ABC_tran_2 PF12848.2 KEY68234.1 - 2 8.3 9.9 3.2 7.6 6.9 1.3 1 0 0 1 1 1 0 ABC transporter DivIC PF04977.10 KEY68234.1 - 8.6 5.9 8.4 1.1 8.7 1.4 2.1 1 1 1 2 2 2 0 Septum formation initiator Zn_Tnp_IS1 PF03811.8 KEY68235.1 - 0.017 14.6 1.5 0.026 14.0 1.0 1.3 1 0 0 1 1 1 0 InsA N-terminal domain Cu-oxidase_2 PF07731.9 KEY68236.1 - 2.9e-23 81.9 1.6 1.4e-21 76.4 1.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 KEY68236.1 - 2.2e-17 62.8 0.6 4.3e-17 61.9 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 KEY68236.1 - 0.00038 20.3 0.0 0.0013 18.6 0.0 1.9 1 1 0 1 1 1 1 Multicopper oxidase FtsH_ext PF06480.10 KEY68237.1 - 0.097 12.8 0.1 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 FtsH Extracellular BAF1_ABF1 PF04684.8 KEY68238.1 - 0.0019 17.1 20.4 0.0019 17.1 14.2 1.7 2 0 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor Gly-zipper_OmpA PF13436.1 KEY68238.1 - 0.77 9.4 9.9 0.23 11.1 4.4 1.9 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Med15 PF09606.5 KEY68238.1 - 1.3 7.0 38.9 0.012 13.9 21.1 1.8 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal zf-UBR PF02207.15 KEY68239.1 - 4.3e-15 55.1 6.9 4.3e-15 55.1 4.8 3.2 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) MCM PF00493.18 KEY68240.1 - 4.8e-138 459.4 0.0 4.8e-138 459.4 0.0 1.8 2 0 0 2 2 2 1 MCM2/3/5 family MCM2_N PF12619.3 KEY68240.1 - 9e-34 116.7 33.2 9e-34 116.7 23.0 2.2 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 KEY68240.1 - 1.7e-20 73.6 0.0 3.7e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KEY68240.1 - 1.5e-07 30.8 0.0 8e-06 25.1 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KEY68240.1 - 2.6e-05 23.9 0.0 5.8e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KEY68240.1 - 0.0039 16.6 0.2 0.027 13.9 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 KEY68240.1 - 0.0088 15.6 0.0 0.037 13.6 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) zf-TFIIB PF13453.1 KEY68240.1 - 0.015 14.5 1.5 0.032 13.4 1.0 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger Zn_ribbon_2 PF12674.2 KEY68240.1 - 0.64 10.3 2.9 0.58 10.5 0.6 2.0 2 0 0 2 2 2 0 Putative zinc ribbon domain DUF4386 PF14329.1 KEY68241.1 - 0.013 14.9 0.5 0.013 14.9 0.3 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4386) Sugar_tr PF00083.19 KEY68243.1 - 2.4e-114 382.4 29.8 2.7e-114 382.2 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY68243.1 - 9.3e-17 60.7 35.2 9.3e-17 60.7 24.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_C2 PF00648.16 KEY68244.1 - 2.1e-55 187.8 2.9 1.9e-37 128.8 1.1 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease zf-CCHC PF00098.18 KEY68245.1 - 5.7e-44 146.0 58.3 4e-08 32.8 2.0 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 KEY68245.1 - 8e-10 38.2 41.0 0.074 12.7 0.7 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 KEY68245.1 - 4.9e-06 26.1 40.8 0.075 12.7 0.0 6.9 4 2 2 6 6 6 5 Zinc knuckle zf-CCHC_6 PF15288.1 KEY68245.1 - 0.07 12.8 0.1 0.07 12.8 0.1 6.8 6 1 1 7 7 7 0 Zinc knuckle zf-CCHC_2 PF13696.1 KEY68245.1 - 0.08 12.4 0.4 0.08 12.4 0.3 7.1 4 2 3 7 7 7 0 Zinc knuckle WD40 PF00400.27 KEY68247.1 - 2.6e-53 176.0 0.2 4.1e-07 29.6 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KEY68247.1 - 7.7e-05 21.6 3.7 0.076 11.7 0.3 3.3 1 1 3 4 4 4 2 Nup133 N terminal like BBS2_Mid PF14783.1 KEY68247.1 - 0.013 15.2 0.0 10 5.9 0.0 3.0 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region SGL PF08450.7 KEY68247.1 - 0.018 14.4 0.2 0.15 11.4 0.0 2.3 1 1 1 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region TRAPP PF04051.11 KEY68248.1 - 7.1e-37 126.2 0.0 8.5e-37 126.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PqqD PF05402.7 KEY68248.1 - 0.094 12.7 0.1 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) DUF4250 PF14056.1 KEY68248.1 - 0.18 11.5 1.0 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) Glyco_hydro_16 PF00722.16 KEY68250.1 - 8.7e-19 67.5 0.1 1.3e-18 66.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 KEY68250.1 - 1e-08 33.8 0.1 0.001 17.3 0.0 2.0 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) STE2 PF02116.10 KEY68253.1 - 9.3e-43 146.2 17.8 1.1e-42 146.0 12.3 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR UEV PF05743.8 KEY68254.1 - 1.2e-29 102.5 0.2 1.8e-29 101.8 0.1 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 KEY68254.1 - 1.2e-22 79.2 0.0 2.7e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 KEY68254.1 - 0.016 14.6 0.3 0.032 13.6 0.2 1.5 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme NTR2 PF15458.1 KEY68254.1 - 0.29 10.3 1.6 0.43 9.7 1.1 1.3 1 0 0 1 1 1 0 Nineteen complex-related protein 2 IDO PF01231.13 KEY68255.1 - 7.3e-173 574.8 0.0 8.4e-173 574.6 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase RNA_pol_Rpb2_6 PF00562.23 KEY68256.1 - 4.7e-125 417.3 0.2 1.9e-124 415.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KEY68256.1 - 1.9e-51 173.8 0.0 3.2e-51 173.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KEY68256.1 - 4e-45 153.5 0.0 8.4e-45 152.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KEY68256.1 - 1.2e-30 105.5 0.0 3e-30 104.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 KEY68256.1 - 9.1e-24 83.1 0.2 2.2e-23 81.9 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 KEY68256.1 - 9.6e-23 79.7 0.0 1.9e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 KEY68256.1 - 1.1e-18 66.7 0.2 3.1e-18 65.3 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 Lant_dehyd_N PF04737.8 KEY68256.1 - 0.028 14.4 0.1 0.079 12.9 0.0 1.7 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus V-ATPase_G PF03179.10 KEY68258.1 - 1.1e-33 115.7 18.5 1.2e-33 115.5 12.8 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 KEY68258.1 - 0.0027 17.4 20.9 0.017 14.8 8.3 2.0 1 1 1 2 2 2 2 ATP synthase B/B' CF(0) DUF4604 PF15377.1 KEY68258.1 - 0.018 15.2 14.2 0.022 14.9 9.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) YusW PF14039.1 KEY68258.1 - 0.035 14.3 4.0 0.057 13.7 2.8 1.3 1 0 0 1 1 1 0 YusW-like protein Nop25 PF09805.4 KEY68258.1 - 0.16 12.0 17.9 0.21 11.6 12.4 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Striatin PF08232.7 KEY68258.1 - 0.32 11.3 9.5 0.43 10.9 6.6 1.1 1 0 0 1 1 1 0 Striatin family DUF3552 PF12072.3 KEY68258.1 - 0.43 9.7 21.3 0.036 13.2 9.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Vfa1 PF08432.5 KEY68258.1 - 0.58 10.1 14.1 0.64 10.0 9.8 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ATP11 PF06644.6 KEY68258.1 - 0.64 9.4 10.2 0.79 9.1 7.1 1.0 1 0 0 1 1 1 0 ATP11 protein DUF2203 PF09969.4 KEY68258.1 - 0.91 9.7 5.3 1.2 9.3 3.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) TRAP_alpha PF03896.11 KEY68258.1 - 1.2 8.0 5.6 1.4 7.8 3.9 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit OmpH PF03938.9 KEY68258.1 - 1.6 8.6 15.1 1.9 8.3 10.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TPR_20 PF14561.1 KEY68258.1 - 1.9 8.6 6.8 0.55 10.3 1.9 1.8 1 1 1 2 2 2 0 Tetratricopeptide repeat SAPS PF04499.10 KEY68258.1 - 2.5 6.6 7.5 2.5 6.6 5.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1910 PF08928.5 KEY68258.1 - 3 7.8 5.9 4.2 7.4 4.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) HrpE PF06188.7 KEY68258.1 - 3.1 7.4 10.1 29 4.3 7.0 1.9 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E Ycf1 PF05758.7 KEY68258.1 - 3.3 5.3 10.3 3.7 5.1 7.2 1.0 1 0 0 1 1 1 0 Ycf1 DUF3987 PF13148.1 KEY68258.1 - 4.3 5.7 8.9 4.8 5.6 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF16 PF01519.11 KEY68258.1 - 4.4 7.5 11.6 8.1 6.7 8.1 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 GAGA_bind PF06217.7 KEY68258.1 - 4.5 7.1 7.8 5 6.9 5.4 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family RRF PF01765.14 KEY68258.1 - 4.8 6.6 17.0 9.5 5.6 11.8 1.5 1 1 0 1 1 1 0 Ribosome recycling factor CENP-H PF05837.7 KEY68258.1 - 7.1 6.8 11.9 14 5.9 7.7 1.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Atg14 PF10186.4 KEY68258.1 - 8.2 5.2 11.4 9.1 5.1 7.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 vATP-synt_E PF01991.13 KEY68258.1 - 8.4 5.6 21.5 2.9 7.1 9.2 2.0 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit CTNNBL PF08216.6 KEY68259.1 - 3.8e-35 119.7 1.3 1.7e-34 117.6 0.0 2.7 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 KEY68259.1 - 0.12 12.2 3.7 6.3 6.7 0.0 4.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat MIT PF04212.13 KEY68260.1 - 4.5e-12 45.6 1.7 8.7e-12 44.7 1.2 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Cellulase PF00150.13 KEY68261.1 - 6.4e-16 58.3 2.3 8.2e-16 58.0 1.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KEY68261.1 - 3.9e-14 52.0 10.1 9.6e-14 50.7 7.0 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Cellulase-like PF12876.2 KEY68261.1 - 9.4e-09 35.6 0.0 1.9e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 KEY68261.1 - 0.0024 17.0 0.1 0.018 14.1 0.0 2.1 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_10 PF00331.15 KEY68261.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Glyco_hydro_2_C PF02836.12 KEY68261.1 - 0.016 14.0 0.0 0.037 12.9 0.0 1.4 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Patatin PF01734.17 KEY68262.1 - 1.3e-25 90.5 0.3 3e-25 89.3 0.2 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase Bac_luciferase PF00296.15 KEY68263.1 - 4.5e-58 196.7 0.1 6.7e-58 196.2 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase ADH_N PF08240.7 KEY68265.1 - 6.9e-12 45.0 0.0 1.8e-11 43.7 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY68265.1 - 7e-08 32.0 1.7 8e-08 31.8 0.4 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Transp_cyt_pur PF02133.10 KEY68266.1 - 3.9e-66 223.4 35.1 4.5e-66 223.2 24.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.11 KEY68267.1 - 7e-39 133.5 21.1 9.7e-39 133.0 14.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY68267.1 - 9.6e-13 47.5 16.9 5.9e-12 44.8 11.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 KEY68267.1 - 0.013 13.5 0.4 0.032 12.2 0.3 1.6 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Bac_luciferase PF00296.15 KEY68268.1 - 1.7e-55 188.2 0.0 2.7e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Zn_clus PF00172.13 KEY68269.1 - 6.2e-09 35.6 8.8 1.1e-08 34.7 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAP PF00956.13 KEY68270.1 - 1.8e-37 128.7 1.5 1.8e-37 128.7 1.1 1.5 1 1 1 2 2 2 1 Nucleosome assembly protein (NAP) DHH PF01368.15 KEY68271.1 - 4.8e-12 45.7 0.0 8.2e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 DHH family Aldo_ket_red PF00248.16 KEY68272.1 - 3.2e-62 209.9 0.0 3.6e-62 209.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FliG_M PF14841.1 KEY68272.1 - 0.0078 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 FliG middle domain MFS_1 PF07690.11 KEY68273.1 - 9.6e-29 100.1 63.7 6.4e-24 84.3 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY68273.1 - 5.4e-10 38.4 31.9 1.9e-05 23.4 9.0 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KEY68273.1 - 1.3e-07 30.3 10.4 1.3e-07 30.3 7.2 2.0 1 1 1 2 2 2 1 MFS/sugar transport protein SET PF00856.23 KEY68274.1 - 4.3e-11 43.3 0.4 4.1e-10 40.2 0.3 2.1 1 1 0 1 1 1 1 SET domain TRAP-gamma PF07074.7 KEY68275.1 - 0.96 8.9 5.5 4.5 6.7 2.2 2.4 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) p450 PF00067.17 KEY68276.1 - 2e-54 184.8 0.0 2.9e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KEY68277.1 - 1.6e-37 129.1 0.0 2.3e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ctr PF04145.10 KEY68277.1 - 0.037 14.0 0.0 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 Ctr copper transporter family p450 PF00067.17 KEY68278.1 - 9.8e-24 83.6 0.0 1.6e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Epimerase PF01370.16 KEY68279.1 - 9.6e-12 44.8 0.0 1.5e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY68279.1 - 7.6e-08 32.5 0.1 1.3e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KEY68279.1 - 2.2e-06 26.7 0.2 5.3e-05 22.2 0.1 2.1 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 KEY68279.1 - 4.3e-05 22.3 0.1 8.3e-05 21.4 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KEY68279.1 - 0.00016 21.0 0.2 0.00023 20.4 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family Ank_2 PF12796.2 KEY68280.1 - 5.3e-49 164.4 2.0 7.9e-18 64.5 0.1 5.9 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KEY68280.1 - 7.5e-38 126.4 19.1 1.8e-09 36.9 0.0 11.1 10 1 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.1 KEY68280.1 - 1.2e-32 108.6 7.3 7.1e-07 28.8 0.0 11.6 11 0 0 11 11 11 7 Ankyrin repeat Ank_4 PF13637.1 KEY68280.1 - 2.1e-29 101.3 7.4 5.2e-05 23.6 0.0 8.8 3 2 7 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY68280.1 - 2.8e-26 90.9 8.1 3.2e-06 27.1 0.2 8.6 4 2 5 9 9 9 7 Ankyrin repeats (many copies) NACHT PF05729.7 KEY68280.1 - 7.8e-07 28.8 0.0 2.8e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KEY68280.1 - 2.1e-06 27.8 0.0 6.7e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain Smr PF01713.16 KEY68280.1 - 0.0097 16.0 0.2 0.091 12.9 0.1 2.5 2 0 0 2 2 2 1 Smr domain GMC_oxred_N PF00732.14 KEY68282.1 - 1.3e-44 152.5 0.0 2e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY68282.1 - 1.7e-23 83.5 0.0 3.4e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KEY68282.1 - 0.0002 20.3 0.0 0.00068 18.5 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KEY68282.1 - 0.00094 18.3 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 KEY68282.1 - 0.0012 18.8 0.2 0.0031 17.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEY68282.1 - 0.0024 16.8 0.3 0.015 14.1 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEY68282.1 - 0.0066 16.5 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY68282.1 - 0.013 14.3 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.13 KEY68282.1 - 0.017 15.0 0.1 0.12 12.4 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.1 KEY68282.1 - 0.055 13.2 0.0 0.37 10.5 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KEY68282.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEY68282.1 - 0.15 10.5 0.0 0.23 9.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 KEY68282.1 - 0.17 10.8 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 KEY68282.1 - 0.27 10.0 0.0 0.38 9.5 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Podoplanin PF05808.6 KEY68283.1 - 0.001 18.6 0.4 0.0019 17.8 0.3 1.5 1 0 0 1 1 1 1 Podoplanin Herpes_gE PF02480.11 KEY68283.1 - 0.019 13.2 0.0 0.028 12.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.10 KEY68283.1 - 0.06 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.15 KEY68283.1 - 0.1 12.2 0.5 0.21 11.2 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain DUF1517 PF07466.6 KEY68283.1 - 0.47 9.3 2.8 0.72 8.7 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Lamp PF01299.12 KEY68283.1 - 5.1 6.1 11.6 1.9 7.5 0.4 2.2 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) YtxH PF12732.2 KEY68283.1 - 9.6 6.6 7.3 92 3.5 0.0 2.3 2 0 0 2 2 2 0 YtxH-like protein ADH_N PF08240.7 KEY68284.1 - 1.4e-29 101.9 0.4 2.3e-29 101.3 0.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY68284.1 - 3.9e-25 87.9 0.1 6.1e-25 87.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY68284.1 - 0.00061 20.6 0.0 0.0011 19.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1537 PF07005.6 KEY68284.1 - 0.022 14.4 0.4 0.035 13.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF1537 ThiF PF00899.16 KEY68284.1 - 0.16 11.7 1.2 0.3 10.8 0.8 1.4 1 0 0 1 1 1 0 ThiF family COesterase PF00135.23 KEY68285.1 - 7.3e-93 312.0 0.0 3.2e-81 273.6 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KEY68285.1 - 6.5e-08 32.4 0.1 1.8e-07 30.9 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY68285.1 - 0.0084 15.8 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family CRAL_TRIO PF00650.15 KEY68288.1 - 6.6e-24 84.1 0.0 9.2e-24 83.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KEY68288.1 - 9.3e-05 22.4 0.0 0.00021 21.3 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Lactonase PF10282.4 KEY68289.1 - 2.1e-84 283.5 0.0 2.7e-84 283.1 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller CDC45 PF02724.9 KEY68296.1 - 0.0086 14.1 0.0 0.012 13.7 0.0 1.1 1 0 0 1 1 1 1 CDC45-like protein ADH_N PF08240.7 KEY68299.1 - 1.5e-08 34.3 0.0 7.3e-08 32.1 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY68299.1 - 1.1e-06 28.2 0.0 2.3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ank_2 PF12796.2 KEY68300.1 - 1.2e-18 67.2 0.4 1.6e-10 41.1 0.1 3.7 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEY68300.1 - 4.5e-16 57.7 8.2 3e-07 29.9 0.1 5.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.1 KEY68300.1 - 1.9e-14 52.3 4.1 0.0015 18.5 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 KEY68300.1 - 1.6e-12 47.5 3.8 6.3e-05 23.3 0.1 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY68300.1 - 8.1e-11 41.8 5.1 0.0033 17.6 0.0 5.1 3 2 2 5 5 5 5 Ankyrin repeats (many copies) DUF3850 PF12961.2 KEY68301.1 - 0.039 13.9 0.0 0.074 13.0 0.0 1.5 1 1 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3850) Transp_cyt_pur PF02133.10 KEY68302.1 - 2.5e-98 329.5 39.4 2.8e-98 329.3 27.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin adh_short PF00106.20 KEY68303.1 - 1.4e-27 96.6 1.0 2e-27 96.1 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY68303.1 - 5.2e-17 62.0 0.2 7e-17 61.6 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY68303.1 - 8.3e-14 51.9 0.1 1e-13 51.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 KEY68303.1 - 4.7e-06 25.7 0.1 6.7e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KEY68303.1 - 6.6e-06 26.2 0.0 0.00039 20.5 0.1 2.4 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 KEY68303.1 - 0.00034 20.1 0.1 0.00059 19.3 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 KEY68303.1 - 0.0035 16.7 0.1 0.015 14.7 0.0 2.1 3 0 0 3 3 3 1 Glycosyl transferase WecB/TagA/CpsF family F420_oxidored PF03807.12 KEY68303.1 - 0.017 15.5 0.8 0.039 14.3 0.2 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 KEY68303.1 - 0.026 13.4 0.2 0.044 12.6 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain p450 PF00067.17 KEY68305.1 - 3.1e-39 134.7 0.0 4e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SMP PF04927.7 KEY68306.1 - 0.00013 21.8 4.0 0.00026 20.8 2.7 1.5 1 0 0 1 1 1 1 Seed maturation protein DUF680 PF05079.7 KEY68306.1 - 3.2 8.3 7.9 1.8 9.0 4.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF680) Herpes_US9 PF06072.6 KEY68307.1 - 0.029 14.2 2.3 0.042 13.6 1.6 1.2 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Ras PF00071.17 KEY68308.1 - 6.8e-38 129.5 0.0 5.2e-37 126.7 0.0 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KEY68308.1 - 1.4e-13 51.3 0.0 4.4e-13 49.7 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KEY68308.1 - 0.0001 21.6 0.0 0.0012 18.1 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.1 KEY68308.1 - 0.002 18.1 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEY68308.1 - 0.005 16.9 0.0 0.39 10.8 0.0 2.5 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.17 KEY68308.1 - 0.099 11.4 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain GTP_EFTU PF00009.22 KEY68308.1 - 0.13 11.6 0.0 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RRM_1 PF00076.17 KEY68310.1 - 1.4e-14 53.4 0.0 1e-11 44.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY68310.1 - 7.3e-10 38.6 0.0 1.8e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Isochorismatase PF00857.15 KEY68311.1 - 3.6e-16 59.5 0.0 5.9e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family TrbH PF07283.6 KEY68311.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 Conjugal transfer protein TrbH DUF1100 PF06500.6 KEY68312.1 - 0.099 11.1 0.1 0.15 10.6 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF329 PF03884.9 KEY68312.1 - 0.72 9.4 9.0 1.1 8.9 3.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF329) Zn_clus PF00172.13 KEY68313.1 - 0.0014 18.5 10.9 0.0024 17.7 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SF3b10 PF07189.6 KEY68314.1 - 1.4e-42 143.3 0.0 1.6e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) MAGE PF01454.14 KEY68315.1 - 1.9e-41 141.5 0.0 2.5e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 MAGE family Fe_dep_repress PF01325.14 KEY68315.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain CDC45 PF02724.9 KEY68315.1 - 2.2 6.2 5.3 2.8 5.8 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF904 PF06005.7 KEY68315.1 - 3.8 7.8 6.0 1.5 9.1 0.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF904) SLS PF14611.1 KEY68316.1 - 6.6e-30 104.0 0.2 1.3e-29 103.1 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator GTP_EFTU PF00009.22 KEY68317.1 - 7.7e-58 195.0 0.0 1.1e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KEY68317.1 - 4.2e-36 123.0 0.0 1.1e-35 121.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KEY68317.1 - 1.2e-16 60.5 0.5 1.2e-16 60.5 0.4 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEY68317.1 - 0.00051 19.9 0.2 0.0018 18.1 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 KEY68317.1 - 0.0021 17.6 0.1 0.0053 16.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 PDZ PF00595.19 KEY68317.1 - 0.073 13.2 0.7 0.41 10.8 0.1 2.6 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) MFS_1 PF07690.11 KEY68318.1 - 8.6e-40 136.5 37.9 3.6e-37 127.8 13.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY68318.1 - 6.6e-09 34.8 5.5 6.6e-09 34.8 3.8 1.8 2 1 0 2 2 2 1 Sugar (and other) transporter DUF1129 PF06570.6 KEY68318.1 - 0.068 12.4 0.3 2 7.7 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) p450 PF00067.17 KEY68319.1 - 4e-44 150.9 0.0 5.7e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Yae1_N PF09811.4 KEY68320.1 - 1.8e-13 49.7 1.0 3e-13 49.0 0.7 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Romo1 PF10247.4 KEY68320.1 - 0.078 13.1 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 DUF2796 PF10986.3 KEY68321.1 - 0.18 11.8 5.9 0.28 11.1 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) CENP-O PF09496.5 KEY68322.1 - 2.5e-22 78.9 0.0 4.5e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component Acatn PF13000.2 KEY68323.1 - 5.5e-151 503.7 23.8 5.7e-78 262.7 6.2 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DFP PF04127.10 KEY68324.1 - 1.5e-12 47.5 0.0 2.4e-05 24.0 0.0 3.1 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein MFS_1 PF07690.11 KEY68325.1 - 4.6e-35 120.9 45.0 4.6e-35 120.9 31.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY68325.1 - 7.3e-07 28.1 43.4 3.3e-06 25.9 12.4 3.1 2 2 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KEY68325.1 - 0.077 11.3 36.6 0.021 13.2 13.1 2.4 1 1 1 2 2 2 0 MFS/sugar transport protein Wbp11 PF09429.5 KEY68326.1 - 2.7e-19 68.9 16.5 2.7e-19 68.9 11.5 2.5 3 0 0 3 3 3 1 WW domain binding protein 11 DUF2294 PF10057.4 KEY68326.1 - 0.0082 15.7 0.6 0.014 15.0 0.4 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2294) Lipoprotein_7 PF01540.11 KEY68326.1 - 0.032 13.2 2.7 0.049 12.7 1.9 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein DUF3450 PF11932.3 KEY68326.1 - 1.2 8.3 7.8 1.9 7.6 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IncA PF04156.9 KEY68326.1 - 2.8 7.5 5.5 5.5 6.5 3.8 1.5 1 0 0 1 1 1 0 IncA protein GATA PF00320.22 KEY68327.1 - 1.4e-16 59.5 1.9 3.3e-16 58.3 1.3 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 KEY68327.1 - 1.7e-10 40.2 0.8 3.4e-10 39.2 0.5 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Pkinase PF00069.20 KEY68328.1 - 6.7e-59 199.1 0.0 6e-58 196.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY68328.1 - 5.8e-29 100.9 0.5 1.2e-20 73.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 KEY68328.1 - 1.8e-06 28.3 3.3 1.8e-06 28.3 0.3 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 KEY68328.1 - 0.0011 17.9 0.0 0.0053 15.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KEY68328.1 - 0.0028 17.4 1.3 0.18 11.5 0.0 3.5 2 1 2 4 4 4 1 Phosphotransferase enzyme family ORC6 PF05460.8 KEY68328.1 - 3.2 6.7 10.4 5.7 5.9 7.2 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Defensin_propep PF00879.13 KEY68329.1 - 0.12 12.3 1.4 0.36 10.8 0.0 2.2 2 0 0 2 2 2 0 Defensin propeptide Bax1-I PF01027.15 KEY68329.1 - 0.14 11.7 3.7 0.063 12.8 0.8 1.7 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Pyrid_oxidase_2 PF13883.1 KEY68330.1 - 1.9e-41 141.6 0.0 2.6e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase APH PF01636.18 KEY68331.1 - 4.2e-16 59.4 0.0 7.7e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Med12 PF09497.5 KEY68332.1 - 3.5e-27 94.1 0.5 9.3e-27 92.8 0.2 2.0 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 RhoGAP PF00620.22 KEY68333.1 - 6.1e-48 162.2 0.0 1.4e-47 161.1 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 KEY68333.1 - 1.2e-12 47.8 0.2 1.2e-12 47.8 0.2 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain TPR_MLP1_2 PF07926.7 KEY68333.1 - 0.0086 15.8 1.6 0.0086 15.8 1.1 2.3 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein DnaI_N PF07319.6 KEY68333.1 - 0.098 12.9 1.9 0.41 10.9 0.0 2.7 3 0 0 3 3 3 0 Primosomal protein DnaI N-terminus DUF4407 PF14362.1 KEY68333.1 - 0.1 11.5 3.4 0.16 10.8 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF59 PF01883.14 KEY68334.1 - 4.3e-06 26.6 0.0 1.3e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function DUF59 GTP_EFTU PF00009.22 KEY68335.1 - 2.8e-40 137.7 0.0 4.3e-40 137.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KEY68335.1 - 1.4e-26 92.3 0.0 4.5e-26 90.7 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KEY68335.1 - 1e-17 63.7 0.0 2.4e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KEY68335.1 - 7.9e-09 35.5 0.0 2e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KEY68335.1 - 1.9e-07 30.8 0.1 1.1e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KEY68335.1 - 3.5e-05 23.7 0.1 7.1e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEY68335.1 - 0.00041 20.8 0.0 0.00087 19.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KEY68335.1 - 0.03 13.5 0.1 0.13 11.4 0.0 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KEY68335.1 - 0.27 9.8 0.1 0.46 9.1 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Thiolase_N PF00108.18 KEY68336.1 - 5.3e-97 323.9 0.2 1e-96 323.0 0.0 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KEY68336.1 - 1e-47 160.5 0.7 3.2e-46 155.7 0.2 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KEY68336.1 - 1e-06 28.4 1.6 4.4e-05 23.0 0.4 2.4 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KEY68336.1 - 0.0002 21.1 0.2 1.9 8.3 0.0 3.4 2 1 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.5 KEY68336.1 - 0.34 10.5 2.8 6.8 6.4 0.0 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PAH PF02671.16 KEY68337.1 - 1.8e-46 155.5 0.8 5.6e-18 64.3 0.5 4.0 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 KEY68337.1 - 8.2e-39 131.4 0.0 2.1e-38 130.1 0.0 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor ABC2_membrane_3 PF12698.2 KEY68337.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Peptidase_M1 PF01433.15 KEY68338.1 - 2.8e-10 39.8 0.0 0.00041 19.5 0.0 3.1 3 0 0 3 3 3 2 Peptidase family M1 HEAT_2 PF13646.1 KEY68338.1 - 6.9e-05 23.0 0.1 0.17 12.2 0.0 3.5 3 0 0 3 3 3 2 HEAT repeats SAS4 PF15460.1 KEY68339.1 - 1.9e-35 120.7 0.2 9.1e-35 118.5 0.1 2.2 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Nop14 PF04147.7 KEY68339.1 - 0.0039 15.2 11.9 0.0055 14.7 8.3 1.2 1 0 0 1 1 1 1 Nop14-like family CamS PF07537.6 KEY68339.1 - 0.049 12.6 0.4 0.15 11.0 0.0 1.8 2 0 0 2 2 2 0 CamS sex pheromone cAM373 precursor BTV_NS2 PF04514.7 KEY68339.1 - 0.13 11.1 7.1 0.23 10.3 4.9 1.5 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CDC45 PF02724.9 KEY68339.1 - 1 7.3 13.8 1.6 6.6 9.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Adaptin_binding PF10199.4 KEY68339.1 - 3.7 7.8 14.5 1.5 9.0 7.6 2.2 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 PX PF00787.19 KEY68340.1 - 3.5e-21 75.1 0.0 3.9e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 PX domain PIG-X PF08320.7 KEY68340.1 - 0.029 13.6 0.0 0.038 13.2 0.0 1.1 1 0 0 1 1 1 0 PIG-X / PBN1 IQ PF00612.22 KEY68342.1 - 0.00011 21.5 0.1 0.00027 20.3 0.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Cadherin_C PF01049.12 KEY68342.1 - 0.028 14.4 1.0 0.028 14.4 0.7 2.5 2 1 0 2 2 2 0 Cadherin cytoplasmic region U3_snoRNA_assoc PF08297.6 KEY68342.1 - 4.8 7.5 12.8 3.5 7.9 0.2 3.4 3 0 0 3 3 3 0 U3 snoRNA associated PQ-loop PF04193.9 KEY68343.1 - 5.4e-23 80.3 6.0 5.8e-14 51.3 1.3 2.5 2 0 0 2 2 2 2 PQ loop repeat ADH_N PF08240.7 KEY68344.1 - 1.3e-10 40.9 2.7 2.1e-10 40.3 0.2 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KEY68344.1 - 0.00013 22.8 0.0 0.00026 21.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Cupin_2 PF07883.6 KEY68344.1 - 0.15 11.5 0.4 0.35 10.3 0.3 1.5 1 0 0 1 1 1 0 Cupin domain zf-RING_2 PF13639.1 KEY68345.1 - 3.2e-09 36.4 4.8 3.2e-09 36.4 3.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 KEY68345.1 - 1.5e-06 27.8 0.8 1.5e-06 27.8 0.6 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger SWIM PF04434.12 KEY68345.1 - 6.9e-05 22.2 0.6 0.00013 21.3 0.4 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-rbx1 PF12678.2 KEY68345.1 - 0.00017 21.5 3.0 0.00017 21.5 2.1 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KEY68345.1 - 0.00047 19.7 3.7 0.00047 19.7 2.6 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEY68345.1 - 0.00081 19.3 5.8 0.0026 17.7 4.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 KEY68345.1 - 0.0012 18.4 4.6 0.0026 17.4 3.2 1.6 1 0 0 1 1 1 1 PHD-finger zf-RING_5 PF14634.1 KEY68345.1 - 0.0026 17.4 3.6 0.0026 17.4 2.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain FANCL_C PF11793.3 KEY68345.1 - 0.0042 17.0 5.5 0.0042 17.0 3.8 2.2 2 1 0 2 2 2 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 KEY68345.1 - 0.0064 16.1 2.5 0.0064 16.1 1.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KEY68345.1 - 0.02 14.4 4.9 0.02 14.4 3.4 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KEY68345.1 - 0.038 13.8 3.1 0.14 12.0 2.1 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.1 KEY68345.1 - 0.12 12.0 1.7 0.35 10.6 1.1 1.9 1 1 0 1 1 1 0 Zinc-binding RING-finger RINGv PF12906.2 KEY68345.1 - 0.14 12.2 4.9 0.36 10.9 3.4 1.8 1 0 0 1 1 1 0 RING-variant domain zf-Di19 PF05605.7 KEY68345.1 - 0.5 10.5 4.2 13 5.9 0.0 3.0 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-RING-like PF08746.6 KEY68345.1 - 6.8 6.7 8.7 0.26 11.3 1.1 2.3 3 0 0 3 3 2 0 RING-like domain Rad4 PF03835.10 KEY68346.1 - 5.3e-16 58.3 5.2 1.1e-15 57.3 3.6 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 KEY68346.1 - 2.7e-11 43.6 2.6 5.4e-11 42.6 1.8 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily NAPRTase PF04095.11 KEY68347.1 - 1.8e-55 187.9 0.0 3e-54 183.8 0.0 2.0 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family PQQ_2 PF13360.1 KEY68348.1 - 1.5e-06 27.8 1.2 2.5e-05 23.8 0.2 3.2 2 1 1 3 3 3 2 PQQ-like domain WD40 PF00400.27 KEY68348.1 - 1.9e-06 27.5 9.3 0.14 12.0 0.0 7.2 7 2 0 7 7 7 2 WD domain, G-beta repeat PQQ PF01011.16 KEY68348.1 - 0.0089 15.5 0.1 0.042 13.4 0.0 2.2 2 0 0 2 2 2 1 PQQ enzyme repeat VD10_N PF08476.5 KEY68348.1 - 0.3 10.6 1.7 0.81 9.2 1.2 1.7 1 0 0 1 1 1 0 Viral D10 N-terminal MFS_1 PF07690.11 KEY68350.1 - 5e-27 94.5 63.3 4.8e-18 64.9 20.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEY68350.1 - 7.9e-08 31.1 16.6 7.9e-08 31.1 11.5 2.5 2 1 1 3 3 3 2 MFS/sugar transport protein FHA PF00498.21 KEY68351.1 - 1.9e-09 37.4 0.0 4e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 KEY68351.1 - 0.014 15.5 0.1 0.16 12.1 0.0 2.3 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain IL32 PF15225.1 KEY68351.1 - 0.045 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Interleukin 32 Cyt-b5 PF00173.23 KEY68352.1 - 3.5e-15 55.5 0.0 5.3e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SlyX PF04102.7 KEY68353.1 - 0.03 14.7 0.3 0.14 12.5 0.2 2.2 1 0 0 1 1 1 0 SlyX DnaJ-X PF14308.1 KEY68354.1 - 1.6e-72 243.0 0.4 1.6e-72 243.0 0.3 2.7 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 KEY68354.1 - 4.3e-26 90.4 0.9 1.1e-25 89.1 0.6 1.8 1 0 0 1 1 1 1 DnaJ domain Alb1 PF09135.6 KEY68354.1 - 1.6 9.3 12.3 0.21 12.1 3.1 3.0 3 0 0 3 3 3 0 Alb1 SQS_PSY PF00494.14 KEY68355.1 - 2.6e-39 135.1 0.0 3.5e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Chordopox_E11 PF06138.7 KEY68355.1 - 0.0086 16.1 0.1 5.1 7.2 0.0 2.5 2 0 0 2 2 2 2 Chordopoxvirus E11 protein MPC PF03650.8 KEY68355.1 - 0.028 14.3 0.0 0.08 12.8 0.0 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0041) Peptidase_S8 PF00082.17 KEY68356.1 - 8.7e-47 159.5 17.2 8.7e-47 159.5 11.9 1.5 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 KEY68356.1 - 0.00049 20.6 0.1 0.00098 19.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Arylsulfotran_2 PF14269.1 KEY68357.1 - 8e-58 195.9 0.2 1.4e-57 195.1 0.1 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KEY68357.1 - 2.1e-18 66.1 0.0 1.9e-17 62.9 0.0 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Ada_Zn_binding PF02805.11 KEY68358.1 - 2e-30 104.1 5.4 3.5e-30 103.3 3.7 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 KEY68358.1 - 1.4e-07 31.0 0.0 5.8e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 KEY68358.1 - 6.5e-07 29.3 0.0 1.4e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Abhydrolase_6 PF12697.2 KEY68359.1 - 1.3e-14 54.6 3.2 1.3e-14 54.6 2.2 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY68359.1 - 5.6e-08 32.6 0.1 1.5e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Translin PF01997.11 KEY68360.1 - 4.7e-50 169.9 0.0 5.5e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Translin family Hemerythrin PF01814.18 KEY68360.1 - 0.46 10.6 3.1 2.2 8.4 1.3 2.2 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Mannosyl_trans PF05007.8 KEY68361.1 - 1.5e-79 267.3 11.1 1.9e-79 266.9 7.7 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 KEY68361.1 - 3.8e-10 39.1 14.1 1.2e-09 37.5 9.8 1.8 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 KEY68361.1 - 1.1e-05 25.0 19.5 1.1e-05 25.0 13.5 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF2029) Fungal_trans PF04082.13 KEY68362.1 - 1.8e-12 46.7 0.6 3.4e-12 45.7 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY68362.1 - 3.4e-08 33.2 11.8 6.2e-08 32.4 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 KEY68362.1 - 0.00089 18.9 0.4 0.0027 17.3 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KEY68362.1 - 0.03 13.9 0.7 1 9.0 0.1 2.7 2 0 0 2 2 2 0 F-box domain ZZ PF00569.12 KEY68364.1 - 1.5e-10 40.4 8.5 2.6e-10 39.6 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.27 KEY68364.1 - 4.9e-09 34.8 5.7 0.00041 19.4 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KEY68364.1 - 7.1e-07 28.5 5.5 0.0016 18.1 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 KEY68364.1 - 1.2e-05 25.3 4.7 0.00035 20.6 1.7 3.4 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.1 KEY68364.1 - 0.00024 20.6 2.7 0.7 9.5 0.0 3.4 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 KEY68364.1 - 0.039 13.3 4.3 3 7.3 0.1 3.3 3 0 0 3 3 3 0 EF hand EF-hand_4 PF12763.2 KEY68364.1 - 0.04 13.6 0.1 0.7 9.6 0.0 2.8 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand C1_3 PF07649.7 KEY68364.1 - 0.099 12.6 9.0 0.17 11.9 6.2 1.4 1 0 0 1 1 1 0 C1-like domain HIG_1_N PF04588.8 KEY68365.1 - 9.9e-22 76.4 1.3 1.6e-21 75.7 0.4 1.8 2 0 0 2 2 2 1 Hypoxia induced protein conserved region TAF4 PF05236.9 KEY68365.1 - 0.042 13.1 5.9 0.048 12.9 4.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family ABC_tran_2 PF12848.2 KEY68365.1 - 3.1 7.6 11.6 7.5 6.4 8.0 1.6 1 0 0 1 1 1 0 ABC transporter TLD PF07534.11 KEY68366.1 - 5.5e-31 107.4 0.0 9.9e-31 106.5 0.0 1.4 1 0 0 1 1 1 1 TLD MUG2_C PF08593.5 KEY68366.1 - 1e-07 32.0 0.1 2.3e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal SAPS PF04499.10 KEY68367.1 - 3.4 6.1 8.6 0.93 8.0 4.1 1.4 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein Rootletin PF15035.1 KEY68368.1 - 0.23 11.4 0.2 0.44 10.5 0.1 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Abhydrolase_5 PF12695.2 KEY68369.1 - 1e-15 57.7 0.1 1.7e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY68369.1 - 9.4e-13 48.5 0.8 2.1e-12 47.3 0.4 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KEY68369.1 - 5.1e-08 32.7 0.3 8e-08 32.1 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KEY68369.1 - 3.2e-07 30.1 0.0 4.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KEY68369.1 - 0.00012 21.8 0.1 0.00057 19.6 0.0 2.2 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KEY68369.1 - 0.00017 20.8 0.0 0.00057 19.1 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 KEY68369.1 - 0.0029 17.0 0.1 0.004 16.6 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF818 PF05677.7 KEY68369.1 - 0.022 13.4 0.0 0.03 13.0 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) NMT_C PF02799.10 KEY68370.1 - 4.6e-75 251.1 0.0 6.7e-75 250.6 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 KEY68370.1 - 1.7e-70 235.8 0.0 3.3e-70 234.8 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 KEY68370.1 - 1.1e-06 28.5 0.0 8.9e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.2 KEY68371.1 - 3.8e-22 79.3 0.0 5.1e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY68371.1 - 1.6e-17 63.8 0.0 2.4e-15 56.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY68371.1 - 1.1e-12 47.8 0.0 2.6e-12 46.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEY68371.1 - 0.00022 20.4 0.0 0.1 11.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.5 KEY68371.1 - 0.0033 17.2 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Thioesterase PF00975.15 KEY68371.1 - 0.0039 17.4 0.0 0.0074 16.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain DLH PF01738.13 KEY68371.1 - 0.0069 15.6 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KEY68371.1 - 0.016 14.6 0.0 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PGAP1 PF07819.8 KEY68371.1 - 0.017 14.6 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein BAAT_C PF08840.6 KEY68371.1 - 0.019 14.6 0.0 0.11 12.1 0.0 1.9 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2048 PF09752.4 KEY68371.1 - 0.039 12.8 0.1 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DUF1100 PF06500.6 KEY68371.1 - 0.079 11.5 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Ribophorin_II PF05817.9 KEY68372.1 - 1.6e-17 63.0 0.1 1.9e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Acetyltransf_2 PF00797.12 KEY68373.1 - 1.9e-33 116.0 0.0 2.9e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase Transglut_core2 PF13369.1 KEY68373.1 - 0.045 13.2 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily Peptidase_M28 PF04389.12 KEY68374.1 - 1e-40 139.4 0.0 1.4e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 DUF3744 PF12558.3 KEY68375.1 - 0.12 12.8 0.4 0.4 11.1 0.0 2.1 2 0 0 2 2 2 0 ATP-binding cassette cobalt transporter CDP-OH_P_transf PF01066.16 KEY68376.1 - 5.1e-16 58.8 7.2 5.1e-16 58.8 5.0 2.5 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Bromodomain PF00439.20 KEY68380.1 - 9e-27 92.8 0.3 2e-26 91.7 0.2 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.19 KEY68380.1 - 1.7e-09 37.5 0.2 5.4e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEY68380.1 - 1.9e-09 37.5 0.1 4.3e-09 36.3 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEY68380.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Rad1 PF02144.11 KEY68381.1 - 4.2e-69 232.3 0.0 6.2e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Nop25 PF09805.4 KEY68383.1 - 0.45 10.5 9.1 0.33 11.0 1.2 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) TFIIA PF03153.8 KEY68383.1 - 1.1 9.0 11.2 0.25 11.1 3.0 2.1 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit APC_CDC26 PF10471.4 KEY68384.1 - 7.3e-14 52.2 2.0 1.5e-13 51.3 1.3 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 Metallophos PF00149.23 KEY68385.1 - 5.3e-15 55.3 2.3 1.9e-14 53.5 1.6 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF993 PF06187.6 KEY68385.1 - 0.11 11.0 0.0 0.19 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF993) SRP_SPB PF02978.14 KEY68386.1 - 0.17 12.1 0.7 0.53 10.5 0.5 1.7 2 0 0 2 2 2 0 Signal peptide binding domain IF4E PF01652.13 KEY68388.1 - 3.9e-57 192.3 0.2 5e-57 192.0 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AMP-binding PF00501.23 KEY68389.1 - 2.1e-66 224.0 0.1 1.1e-60 205.1 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 KEY68389.1 - 4e-12 46.8 0.1 1.5e-11 45.0 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pilus_PilP PF11356.3 KEY68389.1 - 0.042 14.0 0.0 1.9 8.8 0.0 3.1 3 0 0 3 3 3 0 Type IV pilus biogenesis BolA PF01722.13 KEY68390.1 - 1.2e-28 98.8 1.5 1.7e-28 98.4 1.0 1.2 1 0 0 1 1 1 1 BolA-like protein PIP5K PF01504.13 KEY68392.1 - 5.5e-56 189.4 0.0 1e-55 188.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 KEY68392.1 - 7e-26 90.8 0.0 1.2e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 KEY68392.1 - 8.2e-13 48.0 9.8 1.9e-12 46.8 6.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger DUF2404 PF10296.4 KEY68392.1 - 0.001 19.1 0.0 0.0062 16.6 0.0 2.2 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) VPS28 PF03997.7 KEY68393.1 - 1.6e-53 181.1 0.0 1.9e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 VPS28 protein GvpG PF05120.7 KEY68393.1 - 1.3 8.9 6.0 2 8.2 0.4 2.3 2 0 0 2 2 2 0 Gas vesicle protein G Noc2 PF03715.8 KEY68394.1 - 5e-119 396.5 0.0 9.9e-119 395.6 0.0 1.5 1 0 0 1 1 1 1 Noc2p family adh_short PF00106.20 KEY68394.1 - 0.1 12.5 0.1 0.98 9.3 0.0 2.4 2 0 0 2 2 2 0 short chain dehydrogenase Cep57_CLD_2 PF14197.1 KEY68395.1 - 3.1e-28 97.4 68.7 6.6e-15 54.8 3.6 7.1 3 1 3 6 6 6 4 Centrosome localisation domain of PPC89 Cep57_MT_bd PF06657.8 KEY68395.1 - 3.5e-27 94.1 0.6 3.5e-27 94.1 0.4 6.0 4 1 1 6 6 6 1 Centrosome microtubule-binding domain of Cep57 DUF904 PF06005.7 KEY68395.1 - 9.4e-06 25.8 67.9 0.008 16.4 3.9 7.9 2 1 4 7 7 7 5 Protein of unknown function (DUF904) CCDC155 PF14662.1 KEY68395.1 - 0.0025 17.4 63.7 0.0082 15.7 0.2 6.0 2 1 3 5 5 5 3 Coiled-coil region of CCDC155 TPR_MLP1_2 PF07926.7 KEY68395.1 - 0.0037 17.0 19.6 0.0037 17.0 13.6 5.5 4 1 2 6 6 6 2 TPR/MLP1/MLP2-like protein DUF2421 PF10334.4 KEY68395.1 - 0.056 13.0 6.3 0.28 10.7 0.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2421) IncA PF04156.9 KEY68395.1 - 4.3 6.8 74.9 0.021 14.4 12.9 6.2 3 1 3 6 6 6 0 IncA protein Glyco_hydro_76 PF03663.9 KEY68396.1 - 1.7e-16 60.6 2.2 3.9e-15 56.0 1.4 2.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 PALP PF00291.20 KEY68397.1 - 5.7e-72 242.5 0.6 7.2e-72 242.1 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 KEY68397.1 - 2.1e-39 132.9 0.0 7.4e-20 70.3 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase cNMP_binding PF00027.24 KEY68399.1 - 7.9e-36 121.7 0.0 2.2e-19 69.0 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 KEY68399.1 - 6.9e-08 31.7 1.8 1.7 8.9 0.0 6.6 6 0 0 6 6 6 2 Leucine Rich repeat F-box-like PF12937.2 KEY68399.1 - 7.5e-06 25.5 0.5 2.8e-05 23.7 0.3 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEY68399.1 - 7e-05 22.3 0.6 7e-05 22.3 0.4 3.3 4 0 0 4 4 4 1 F-box domain LRR_8 PF13855.1 KEY68399.1 - 0.0023 17.6 0.1 0.1 12.3 0.0 2.9 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 KEY68399.1 - 0.013 15.4 3.3 9.3 6.7 0.1 5.6 6 1 1 7 7 7 0 Leucine Rich Repeat HIT PF01230.18 KEY68399.1 - 0.085 13.3 0.1 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 HIT domain LRR_7 PF13504.1 KEY68399.1 - 0.22 11.8 6.7 1e+02 3.8 0.0 5.2 4 1 0 4 4 4 0 Leucine rich repeat Bax1-I PF01027.15 KEY68400.1 - 2.1e-28 99.3 10.0 3.1e-28 98.7 7.0 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PMSR PF01625.16 KEY68401.1 - 1.1e-52 177.9 0.0 1.4e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Sugar_tr PF00083.19 KEY68402.1 - 7.9e-84 281.8 25.7 9.5e-84 281.5 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY68402.1 - 1.7e-15 56.6 44.2 9.2e-15 54.1 12.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_2 PF04909.9 KEY68403.1 - 1.2e-24 87.3 0.1 1.3e-24 87.2 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.13 KEY68404.1 - 7.5e-23 80.7 3.8 1.2e-22 80.1 2.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY68404.1 - 3e-09 36.6 9.2 5.1e-09 35.8 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIP PF00230.15 KEY68405.1 - 2.4e-45 154.7 18.2 3.1e-45 154.3 12.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein 2-Hacid_dh_C PF02826.14 KEY68406.1 - 2.3e-47 160.4 0.1 9.4e-47 158.4 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.20 KEY68406.1 - 2.9e-22 79.3 3.2 2.9e-22 79.3 2.2 2.6 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY68406.1 - 2.9e-10 40.0 0.9 2.9e-10 40.0 0.6 2.5 2 1 0 2 2 2 1 KR domain 2-Hacid_dh PF00389.25 KEY68406.1 - 9.1e-06 25.1 0.0 2.3e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KEY68406.1 - 0.00096 19.0 1.4 0.0054 16.5 0.0 2.8 3 1 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3Beta_HSD PF01073.14 KEY68406.1 - 0.036 12.7 0.1 0.27 9.8 0.1 2.4 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family AraC_binding_2 PF14525.1 KEY68406.1 - 0.048 13.2 1.0 0.1 12.1 0.4 1.8 2 0 0 2 2 2 0 AraC-binding-like domain Ras PF00071.17 KEY68407.1 - 1.8e-33 115.2 0.0 2.6e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEY68407.1 - 6.8e-09 36.2 0.0 1.4e-08 35.2 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEY68407.1 - 8e-09 34.9 0.0 2.3e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family PduV-EutP PF10662.4 KEY68407.1 - 0.062 12.7 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 KEY68407.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Glyco_hydro_2_N PF02837.13 KEY68408.1 - 2.2e-11 43.6 0.1 8.3e-11 41.7 0.1 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KEY68408.1 - 4.5e-11 43.1 2.8 8e-11 42.3 0.0 2.6 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 KEY68408.1 - 0.0012 17.8 0.0 0.0022 16.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF402 PF04167.8 KEY68408.1 - 0.028 14.2 3.9 0.3 10.9 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF402) Peptidase_S8 PF00082.17 KEY68409.1 - 2.5e-43 148.2 21.5 4.1e-43 147.5 14.9 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KEY68409.1 - 1.4e-15 57.5 0.0 2.5e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Malic_M PF03949.10 KEY68410.1 - 6.8e-78 261.7 0.0 1.1e-77 261.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KEY68410.1 - 6.7e-65 218.0 0.0 1.3e-64 217.1 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF2413 PF10310.4 KEY68411.1 - 2.3e-139 465.0 1.1 2.8e-139 464.7 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Gly_rich PF12810.2 KEY68411.1 - 0.045 13.3 0.3 0.095 12.2 0.2 1.5 1 0 0 1 1 1 0 Glycine rich protein GatB_Yqey PF02637.13 KEY68412.1 - 0.14 11.9 3.7 0.44 10.2 2.6 1.8 1 0 0 1 1 1 0 GatB domain Ribosomal_L14 PF00238.14 KEY68413.1 - 8.6e-32 109.4 0.0 9.6e-32 109.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Methyltransf_24 PF13578.1 KEY68414.1 - 3.1e-12 47.2 0.0 5.4e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KEY68414.1 - 4.3e-11 42.2 0.1 6e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KEY68414.1 - 0.027 15.0 0.0 0.071 13.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Fungal_trans PF04082.13 KEY68415.1 - 9.9e-20 70.4 0.0 1.6e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY68415.1 - 1.6e-09 37.5 11.0 2.7e-09 36.7 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDIX PF00293.23 KEY68416.1 - 9.5e-13 47.9 0.0 1.5e-11 44.1 0.0 2.4 1 1 0 1 1 1 1 NUDIX domain Pkinase PF00069.20 KEY68417.1 - 4.9e-37 127.4 0.0 6.5e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY68417.1 - 1.6e-17 63.4 0.0 3.2e-17 62.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY68417.1 - 0.0011 17.9 0.0 0.002 17.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEY68417.1 - 0.0023 17.7 0.0 0.0046 16.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Cactin_mid PF10312.4 KEY68419.1 - 4.9e-59 198.8 3.2 6.9e-59 198.3 2.2 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 KEY68419.1 - 1.3e-55 186.3 4.2 2.2e-55 185.6 2.9 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein DUF4404 PF14357.1 KEY68419.1 - 0.17 12.3 0.8 1.5 9.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) RsbRD_N PF14361.1 KEY68419.1 - 0.18 12.2 2.1 23 5.5 0.9 2.3 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain Fork_head PF00250.13 KEY68420.1 - 4e-16 58.8 0.4 1.3e-15 57.1 0.0 1.9 2 0 0 2 2 2 1 Fork head domain XLF PF09302.6 KEY68421.1 - 1.3e-27 96.6 0.0 2e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 XLF (XRCC4-like factor) FAD_binding_7 PF03441.9 KEY68422.1 - 3.8e-103 344.5 0.0 7.5e-103 343.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KEY68422.1 - 1.1e-38 132.6 0.2 2e-38 131.7 0.1 1.4 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.21 KEY68422.1 - 0.0019 18.3 0.0 0.0052 16.9 0.0 1.7 1 0 0 1 1 1 1 Universal stress protein family Ribosomal_S21e PF01249.13 KEY68423.1 - 1.1e-40 137.4 0.1 1.2e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Slx4 PF09494.5 KEY68424.1 - 9e-24 83.0 0.0 1.6e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Slx4 endonuclease DUF3129 PF11327.3 KEY68425.1 - 1.8e-59 200.6 8.6 2.3e-59 200.3 6.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) I-set PF07679.11 KEY68425.1 - 0.032 14.0 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain Sulfate_transp PF00916.15 KEY68428.1 - 7.1e-55 185.9 10.1 1.2e-54 185.2 7.0 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KEY68428.1 - 1.7e-28 98.1 0.7 1.7e-28 98.1 0.5 3.1 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KEY68428.1 - 2.2e-12 46.4 0.0 6.3e-12 44.9 0.0 1.7 1 1 0 1 1 1 1 STAS domain Cupin_1 PF00190.17 KEY68429.1 - 5.4e-31 106.9 0.0 8.7e-16 57.6 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 KEY68429.1 - 4.9e-28 96.4 0.6 8e-14 50.8 0.2 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KEY68429.1 - 1.8e-09 36.8 0.0 0.0012 18.1 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 KEY68429.1 - 1.4e-06 28.0 0.1 0.0011 18.6 0.0 3.2 1 1 2 3 3 3 2 AraC-like ligand binding domain MannoseP_isomer PF01050.13 KEY68429.1 - 0.00012 21.6 0.0 0.022 14.3 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase 3-HAO PF06052.7 KEY68429.1 - 0.0011 18.4 0.0 0.062 12.7 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase ARD PF03079.9 KEY68429.1 - 0.0057 16.6 0.3 0.98 9.3 0.0 2.2 2 0 0 2 2 2 1 ARD/ARD' family GPI PF06560.6 KEY68429.1 - 0.032 13.2 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Cupin_7 PF12973.2 KEY68429.1 - 0.075 12.8 0.2 0.45 10.3 0.0 2.3 2 0 0 2 2 2 0 ChrR Cupin-like domain DUF1275 PF06912.6 KEY68430.1 - 6.1e-37 126.8 17.9 7.6e-37 126.5 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MFS_1 PF07690.11 KEY68431.1 - 2.2e-29 102.2 34.0 3.2e-29 101.7 23.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Pkinase PF00069.20 KEY68432.1 - 1.9e-73 246.8 0.0 2.8e-73 246.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY68432.1 - 6e-38 130.3 0.0 1.7e-37 128.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY68432.1 - 7.9e-05 21.7 0.2 0.23 10.3 0.0 2.8 2 1 0 2 2 2 2 Kinase-like Pox_ser-thr_kin PF05445.6 KEY68432.1 - 0.035 12.9 0.1 0.061 12.1 0.1 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF4095 PF13338.1 KEY68433.1 - 0.031 14.4 0.1 0.096 12.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4095) JAB PF01398.16 KEY68434.1 - 1.5e-34 118.1 0.0 2.6e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KEY68434.1 - 1.1e-25 89.9 1.2 2.6e-25 88.7 0.8 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KEY68434.1 - 1.5e-08 34.1 0.0 2.5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Hist_deacetyl PF00850.14 KEY68435.1 - 1e-80 271.3 0.0 1.7e-80 270.6 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain RNA_pol_Rpc34 PF05158.7 KEY68436.1 - 2.3e-93 312.9 0.0 2.9e-93 312.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.6 KEY68436.1 - 0.0031 17.8 0.0 0.16 12.3 0.0 3.0 3 0 0 3 3 3 1 Replication protein A C terminal B-block_TFIIIC PF04182.7 KEY68436.1 - 0.11 12.3 0.0 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC Mnd1 PF03962.10 KEY68436.1 - 0.12 11.9 0.9 1.3 8.6 0.1 2.2 2 0 0 2 2 2 0 Mnd1 family Ribosomal_60s PF00428.14 KEY68436.1 - 1.1 9.7 4.4 0.82 10.1 0.4 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein Pro_isomerase PF00160.16 KEY68437.1 - 2.7e-42 144.5 0.5 3.2e-42 144.3 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.15 KEY68438.1 - 6e-47 158.6 0.0 8.7e-47 158.0 0.0 1.2 1 0 0 1 1 1 1 ENTH domain PAT1 PF09770.4 KEY68438.1 - 0.00042 18.7 5.7 0.00059 18.2 4.0 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 ANTH PF07651.11 KEY68438.1 - 0.0018 17.0 0.0 0.0026 16.5 0.0 1.2 1 0 0 1 1 1 1 ANTH domain MARVEL PF01284.18 KEY68439.1 - 1e-06 28.5 14.6 2.3e-06 27.4 10.1 1.6 1 1 0 1 1 1 1 Membrane-associating domain SMN PF06003.7 KEY68440.1 - 2.5 7.1 5.7 2.4 7.1 3.9 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Fungal_trans_2 PF11951.3 KEY68441.1 - 3.9e-49 167.2 0.2 5.7e-49 166.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY68441.1 - 1e-06 28.5 7.2 1.7e-06 27.7 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFCD_C PF12612.3 KEY68441.1 - 0.099 12.0 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal Golgin_A5 PF09787.4 KEY68442.1 - 1.5 7.2 4.7 1.7 7.1 3.3 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 Hemerythrin PF01814.18 KEY68443.1 - 2.7e-09 37.2 4.5 3.4e-09 36.9 3.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF2944 PF11161.3 KEY68443.1 - 1.2 8.7 4.8 3.3 7.3 1.9 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2946) Zip PF02535.17 KEY68444.1 - 1.1e-52 179.0 1.6 1.8e-52 178.3 1.1 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter Sdh_cyt PF01127.17 KEY68444.1 - 0.039 13.7 0.0 0.039 13.7 0.0 3.1 3 1 1 4 4 4 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TPR_11 PF13414.1 KEY68445.1 - 3.5e-55 183.5 30.8 1.1e-17 63.4 0.7 6.3 5 1 2 7 7 7 7 TPR repeat TPR_1 PF00515.23 KEY68445.1 - 1.6e-39 131.8 31.2 1.6e-07 30.5 0.6 9.5 9 1 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 KEY68445.1 - 1.6e-30 102.5 32.1 6.4e-06 25.6 0.2 9.7 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 KEY68445.1 - 9.8e-18 63.8 14.4 4.3e-10 39.3 0.8 5.7 3 3 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEY68445.1 - 4.5e-17 60.9 5.4 0.14 12.8 0.0 8.6 4 3 4 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 KEY68445.1 - 6.7e-17 61.6 12.6 2.7e-05 24.6 0.0 6.7 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 KEY68445.1 - 9.4e-14 50.3 11.6 0.016 15.3 0.1 8.3 7 2 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEY68445.1 - 2.9e-11 42.3 31.7 0.00031 20.2 0.1 7.6 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 KEY68445.1 - 1.1e-10 41.7 12.2 0.00018 21.7 0.1 6.0 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEY68445.1 - 2.5e-07 29.9 9.5 0.016 14.9 0.2 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEY68445.1 - 6.5e-07 29.1 0.4 0.11 12.4 0.0 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 KEY68445.1 - 0.0001 22.3 13.3 0.0018 18.3 1.7 3.6 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KEY68445.1 - 0.0019 18.5 17.1 1.3 9.6 0.0 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.1 KEY68445.1 - 0.0097 15.8 0.4 0.15 12.0 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3568 PF12092.3 KEY68445.1 - 0.01 15.5 0.8 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) TPR_20 PF14561.1 KEY68445.1 - 0.25 11.5 9.8 0.66 10.1 0.1 4.9 4 2 1 5 5 5 0 Tetratricopeptide repeat Glyco_hydro_3 PF00933.16 KEY68446.1 - 3.1e-84 282.5 0.0 4.6e-84 281.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY68446.1 - 6.1e-60 202.5 0.1 3.2e-59 200.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEY68446.1 - 8e-23 80.1 0.2 4.9e-22 77.6 0.1 2.3 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 KEY68446.1 - 0.0013 18.4 0.0 0.0045 16.6 0.0 1.9 2 1 0 2 2 2 1 PA14 domain CARDB PF07705.6 KEY68446.1 - 0.039 14.0 0.1 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 CARDB Pyr_redox_3 PF13738.1 KEY68447.1 - 2.7e-25 89.6 0.0 5.5e-25 88.6 0.0 1.5 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEY68447.1 - 2.6e-12 45.7 0.0 6.4e-12 44.4 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KEY68447.1 - 1.5e-10 40.9 0.0 4e-09 36.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KEY68447.1 - 1.7e-06 27.1 0.0 0.00053 19.0 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 KEY68447.1 - 8.8e-06 25.0 0.3 0.0017 17.4 0.1 2.5 2 1 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 KEY68447.1 - 2e-05 24.4 0.8 4.5 7.0 0.0 4.4 3 1 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KEY68447.1 - 2.5e-05 24.2 0.0 0.061 13.2 0.0 3.1 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEY68447.1 - 8e-05 21.8 0.0 0.0038 16.3 0.0 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KEY68447.1 - 0.0001 21.3 3.1 0.14 11.0 0.0 3.8 3 1 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEY68447.1 - 0.0005 20.4 0.1 1.4 9.4 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY68447.1 - 0.00056 18.9 0.0 0.016 14.1 0.0 3.0 4 0 0 4 4 4 1 Lycopene cyclase protein Shikimate_DH PF01488.15 KEY68447.1 - 0.0033 17.5 0.0 0.071 13.2 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 KEY68447.1 - 0.013 14.5 0.0 0.2 10.6 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 KEY68447.1 - 0.016 14.0 0.0 2.4 6.9 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KEY68447.1 - 0.019 13.8 0.0 0.41 9.4 0.0 2.7 3 0 0 3 3 3 0 FAD binding domain Trp_halogenase PF04820.9 KEY68447.1 - 0.041 12.4 0.0 3.9 6.0 0.0 2.4 2 0 0 2 2 2 0 Tryptophan halogenase p450 PF00067.17 KEY68448.1 - 6.6e-46 156.7 0.0 9.2e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NTR2 PF15458.1 KEY68449.1 - 1.4e-74 250.5 16.1 2.1e-74 250.0 11.2 1.3 1 0 0 1 1 1 1 Nineteen complex-related protein 2 FUSC PF04632.7 KEY68449.1 - 0.56 8.5 2.4 0.8 8.0 1.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family LSM PF01423.17 KEY68450.1 - 5.7e-19 67.4 0.6 6.5e-19 67.2 0.4 1.0 1 0 0 1 1 1 1 LSM domain Rhodanese PF00581.15 KEY68451.1 - 3.9e-09 36.8 0.0 7.7e-09 35.8 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain Amino_oxidase PF01593.19 KEY68452.1 - 1e-56 192.9 0.0 1.3e-56 192.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KEY68452.1 - 1.3e-08 34.7 0.0 5e-08 32.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEY68452.1 - 0.00029 19.8 0.3 0.0016 17.3 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEY68452.1 - 0.00075 19.6 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEY68452.1 - 0.0058 15.7 0.3 0.009 15.0 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KEY68452.1 - 0.0081 15.2 0.4 0.016 14.3 0.0 1.6 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KEY68452.1 - 0.082 11.3 0.1 0.12 10.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Zn_clus PF00172.13 KEY68453.1 - 0.19 11.6 11.2 0.37 10.7 7.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3844 PF12955.2 KEY68454.1 - 6.8e-32 109.6 3.7 6.8e-32 109.6 2.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 KEY68454.1 - 1.7 8.8 10.9 6.2 7.0 7.6 2.0 1 1 0 1 1 1 0 EGF-like domain HLH PF00010.21 KEY68456.1 - 1.3e-09 37.5 0.0 2.4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PTCB-BRCT PF12738.2 KEY68456.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 twin BRCT domain Maf PF02545.9 KEY68457.1 - 7e-44 149.2 0.0 8.4e-44 149.0 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Bromodomain PF00439.20 KEY68458.1 - 6e-30 103.0 0.5 1.6e-14 53.6 0.0 2.5 2 0 0 2 2 2 2 Bromodomain Nop14 PF04147.7 KEY68458.1 - 0.22 9.4 13.7 0.33 8.8 9.5 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 KEY68458.1 - 0.55 9.3 13.1 0.99 8.4 9.1 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 KEY68458.1 - 3.6 5.4 11.4 6 4.7 7.9 1.2 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.6 KEY68458.1 - 5.5 6.4 11.2 9.6 5.6 7.8 1.4 1 0 0 1 1 1 0 PPP4R2 DUF1510 PF07423.6 KEY68458.1 - 6.5 6.0 11.1 13 5.1 7.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nipped-B_C PF12830.2 KEY68460.1 - 0.00058 19.5 0.0 0.00094 18.8 0.0 1.3 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus DUF2408 PF10303.4 KEY68460.1 - 0.033 14.2 0.0 0.13 12.4 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) tRNA-synt_2b PF00587.20 KEY68461.1 - 2.1e-49 167.4 0.0 3.1e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KEY68461.1 - 2.8e-05 23.9 0.0 5.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Basic PF01586.11 KEY68461.1 - 0.081 13.6 0.2 0.2 12.3 0.1 1.6 1 0 0 1 1 1 0 Myogenic Basic domain IBN_N PF03810.14 KEY68462.1 - 3.8e-12 45.9 0.3 1.4e-11 44.0 0.2 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KEY68462.1 - 0.0004 20.3 0.4 0.0048 16.8 0.0 2.9 2 1 0 3 3 3 1 Exportin 1-like protein Cse1 PF08506.5 KEY68462.1 - 0.00048 18.8 0.1 0.0037 15.8 0.0 2.1 2 0 0 2 2 2 1 Cse1 MMS19_C PF12460.3 KEY68462.1 - 0.013 14.2 0.2 0.032 12.9 0.0 1.7 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal SWI-SNF_Ssr4 PF08549.5 KEY68463.1 - 2.2e-188 627.7 11.8 2.6e-188 627.5 8.2 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) 6PGD PF00393.14 KEY68464.1 - 1.5e-135 451.0 0.0 1.9e-135 450.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KEY68464.1 - 5.7e-52 175.8 0.0 8.2e-52 175.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KEY68464.1 - 0.025 14.6 0.0 0.081 12.9 0.0 1.9 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase RRM_1 PF00076.17 KEY68465.1 - 4.9e-17 61.3 0.1 7.7e-17 60.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY68465.1 - 2.7e-12 46.4 0.0 4.4e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY68465.1 - 0.00022 20.9 0.1 0.00038 20.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 KEY68465.1 - 0.081 12.4 0.3 0.16 11.4 0.2 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain TPT PF03151.11 KEY68466.1 - 1.5e-32 112.3 10.8 1.5e-32 112.3 7.5 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KEY68466.1 - 1.1e-05 24.5 17.7 1.1e-05 24.5 12.3 2.0 1 1 0 2 2 2 1 UAA transporter family EamA PF00892.15 KEY68466.1 - 0.00012 22.0 33.5 0.021 14.8 7.3 3.1 2 2 0 2 2 2 2 EamA-like transporter family DUF2615 PF11027.3 KEY68466.1 - 0.01 15.7 0.5 2.7 7.9 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2615) Cation_ATPase_N PF00690.21 KEY68466.1 - 0.065 12.6 0.4 0.2 11.1 0.3 1.8 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus NPCC PF08058.6 KEY68466.1 - 0.082 12.7 0.2 0.19 11.5 0.2 1.6 1 0 0 1 1 1 0 Nuclear pore complex component CD99L2 PF12301.3 KEY68466.1 - 0.42 10.2 4.6 0.081 12.6 0.7 1.6 2 0 0 2 2 2 0 CD99 antigen like protein 2 2TM PF13239.1 KEY68466.1 - 5 7.2 8.6 0.46 10.5 0.1 3.0 2 1 0 2 2 2 0 2TM domain Glyco_hydro_15 PF00723.16 KEY68467.1 - 3.8e-51 174.0 0.0 1.8e-46 158.6 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 MCLC PF05934.6 KEY68467.1 - 0.016 13.4 0.0 0.031 12.5 0.0 1.3 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF3164 PF11363.3 KEY68468.1 - 0.11 11.8 0.3 0.15 11.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3164) HAD PF12710.2 KEY68469.1 - 2.8e-19 70.0 0.1 1.1e-18 68.0 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEY68469.1 - 0.00034 21.0 0.1 0.0012 19.3 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KEY68469.1 - 0.014 15.6 0.1 0.042 14.0 0.1 1.8 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEY68469.1 - 0.026 14.0 0.1 0.18 11.3 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TFIIF_beta PF02270.10 KEY68470.1 - 1.6e-64 218.3 0.3 1.9e-64 218.1 0.2 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Elongin_A PF06881.6 KEY68471.1 - 4.7e-19 68.7 1.8 4.7e-19 68.7 1.3 1.6 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Nucleoplasmin PF03066.10 KEY68471.1 - 0.22 11.0 3.4 0.42 10.1 2.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 KEY68471.1 - 1.5 6.7 4.3 2.5 6.0 3.0 1.3 1 0 0 1 1 1 0 CDC45-like protein E1-E2_ATPase PF00122.15 KEY68472.1 - 3.1e-56 190.0 0.8 7.4e-56 188.7 0.5 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEY68472.1 - 4.3e-41 140.4 4.9 4.3e-41 140.4 3.4 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEY68472.1 - 3.3e-29 102.8 0.0 2.1e-28 100.2 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEY68472.1 - 1.2e-17 63.6 0.0 2.3e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEY68472.1 - 2.2e-14 54.0 0.0 4.6e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEY68472.1 - 7.8e-09 34.8 0.8 6.6e-08 31.9 0.0 2.8 4 0 0 4 4 4 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KEY68472.1 - 5e-05 22.9 0.1 0.00047 19.8 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Band_7 PF01145.20 KEY68473.1 - 2.7e-23 82.8 2.8 3.8e-23 82.3 1.9 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family E_Pc_C PF06752.7 KEY68473.1 - 0.014 14.9 0.1 0.019 14.4 0.1 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Methyltransf_11 PF08241.7 KEY68474.1 - 3.9e-11 43.3 0.0 1.1e-10 41.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY68474.1 - 0.0059 16.3 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY68474.1 - 0.033 14.6 0.0 0.097 13.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KEY68474.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SUI1 PF01253.17 KEY68475.1 - 1.6e-16 59.8 1.4 1.6e-15 56.6 1.0 2.4 1 1 0 1 1 1 1 Translation initiation factor SUI1 DUF4398 PF14346.1 KEY68475.1 - 0.0097 15.9 6.2 0.02 14.9 4.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4398) Nbl1_Borealin_N PF10444.4 KEY68476.1 - 1.1e-15 56.7 4.9 2.4e-15 55.6 0.4 2.4 2 0 0 2 2 2 2 Nbl1 / Borealin N terminal VWA_2 PF13519.1 KEY68477.1 - 2.1e-14 54.0 0.0 2.8e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 KEY68477.1 - 1.1e-09 38.1 0.1 1.6e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 KEY68477.1 - 5.6e-09 35.9 0.6 8.1e-09 35.4 0.4 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 KEY68477.1 - 0.0018 17.7 2.0 0.0018 17.7 1.4 2.2 2 0 0 2 2 2 1 Ubiquitin interaction motif DUF243 PF03103.12 KEY68477.1 - 0.042 13.9 0.2 0.042 13.9 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF243) Sybindin PF04099.7 KEY68478.1 - 1.8e-53 180.0 0.0 2.1e-53 179.8 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KEY68478.1 - 6.4e-08 32.5 0.0 9.8e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Toxin_ToxA PF11584.3 KEY68478.1 - 0.077 12.8 0.0 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 Proteinaceous host-selective toxin ToxA RNA_pol_Rpb4 PF03874.11 KEY68479.1 - 1.8e-28 98.9 4.9 2.1e-28 98.6 3.4 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Spexin PF15171.1 KEY68479.1 - 0.0097 15.8 0.5 0.0097 15.8 0.4 1.8 2 0 0 2 2 2 1 Neuropeptide secretory protein family, NPQ, spexin EphA2_TM PF14575.1 KEY68480.1 - 0.00051 20.3 0.9 0.00073 19.8 0.0 1.7 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Orthoreo_P10 PF07204.6 KEY68480.1 - 0.13 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 FAM176 PF14851.1 KEY68480.1 - 0.39 10.4 4.6 8.5 6.0 3.1 2.3 2 1 0 2 2 2 0 FAM176 family Conotoxin PF02950.12 KEY68480.1 - 0.43 11.3 0.0 0.43 11.3 0.0 3.1 2 1 1 3 3 3 0 Conotoxin Shisa PF13908.1 KEY68480.1 - 0.88 9.7 9.4 7.6 6.6 5.6 2.6 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator CPL PF08144.6 KEY68481.1 - 1.7e-19 70.1 0.0 7.8e-19 67.9 0.0 2.2 2 0 0 2 2 2 1 CPL (NUC119) domain CTI PF06934.6 KEY68481.1 - 0.015 13.5 0.0 0.025 12.8 0.0 1.2 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) DUF4358 PF14270.1 KEY68481.1 - 0.087 12.7 1.3 6.3 6.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) DUF2894 PF11445.3 KEY68481.1 - 3.5 7.8 7.2 15 5.7 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2894) RWD PF05773.17 KEY68482.1 - 8.9e-23 80.3 0.3 1.5e-22 79.6 0.2 1.4 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.21 KEY68482.1 - 0.063 12.6 0.1 0.11 11.9 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme ETC_C1_NDUFA5 PF04716.9 KEY68482.1 - 0.32 10.5 2.7 0.46 10.0 1.0 1.9 2 0 0 2 2 2 0 ETC complex I subunit conserved region TPR_12 PF13424.1 KEY68483.1 - 3.6e-16 58.8 0.0 1.5e-08 34.4 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEY68483.1 - 7.1e-15 54.1 1.8 0.024 15.2 0.0 5.2 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 KEY68483.1 - 1.5e-14 52.6 0.1 6.5e-07 28.7 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEY68483.1 - 4.3e-13 49.5 0.0 1.3e-05 25.7 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEY68483.1 - 4.7e-13 48.5 0.0 5.6e-06 25.9 0.0 4.3 2 2 3 5 5 5 3 TPR repeat TPR_19 PF14559.1 KEY68483.1 - 1.4e-12 47.7 0.1 0.00015 22.0 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEY68483.1 - 7.6e-11 41.1 0.0 4.8e-06 25.9 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEY68483.1 - 1.7e-08 33.6 0.0 5.4e-06 25.8 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEY68483.1 - 2.5e-08 33.0 0.5 0.00037 20.0 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KEY68483.1 - 3.2e-08 33.2 2.9 0.036 14.0 0.0 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEY68483.1 - 1e-06 28.5 0.0 1.6 8.6 0.0 3.6 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 KEY68483.1 - 1.3e-05 25.3 1.0 0.11 12.9 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KEY68483.1 - 1.3e-05 25.2 0.0 0.8 9.8 0.0 3.8 2 2 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KEY68483.1 - 7.4e-05 22.6 0.0 7.1 7.0 0.0 5.5 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 KEY68483.1 - 0.0044 17.3 6.9 0.45 11.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.5 KEY68483.1 - 0.047 13.1 0.7 1.5 8.2 0.1 2.9 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Nucleoplasmin PF03066.10 KEY68483.1 - 0.047 13.1 3.0 0.11 11.9 2.1 1.7 1 0 0 1 1 1 0 Nucleoplasmin TPR_21 PF09976.4 KEY68483.1 - 0.067 13.1 0.5 3.7 7.4 0.2 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Lum_binding PF00677.12 KEY68484.1 - 3.7e-41 138.9 5.1 2.4e-21 75.4 1.2 2.1 2 0 0 2 2 2 2 Lumazine binding domain ERCC4 PF02732.10 KEY68485.1 - 7.2e-32 110.1 0.1 1.2e-31 109.3 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 KEY68485.1 - 0.00019 21.5 0.0 0.00042 20.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain PGM_PMM_I PF02878.11 KEY68486.1 - 1.7e-18 66.4 0.4 4.9e-08 32.5 0.0 3.0 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KEY68486.1 - 1.6e-12 47.6 0.0 6.8e-12 45.6 0.0 2.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KEY68486.1 - 6.2e-10 38.9 0.1 3e-09 36.7 0.1 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 KEY68486.1 - 0.0091 16.0 0.1 0.036 14.0 0.0 2.1 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Methyltransf_31 PF13847.1 KEY68487.1 - 6.2e-11 42.1 0.0 1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEY68487.1 - 8.6e-11 41.4 0.0 1.3e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PRMT5 PF05185.11 KEY68487.1 - 5.4e-10 38.7 0.1 7.1e-10 38.3 0.1 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 KEY68487.1 - 2.1e-07 30.9 0.0 3.8e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY68487.1 - 2.2e-07 31.2 0.0 4.3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY68487.1 - 2.9e-07 31.0 0.0 5.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KEY68487.1 - 3.5e-07 29.2 0.2 5.2e-07 28.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 KEY68487.1 - 1.1e-05 25.7 0.1 5.8e-05 23.3 0.0 2.1 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY68487.1 - 0.00041 20.1 0.0 0.00068 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY68487.1 - 0.00084 18.7 0.2 0.0016 17.8 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 KEY68487.1 - 0.0038 16.3 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KEY68487.1 - 0.0042 17.5 0.0 0.0076 16.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KEY68487.1 - 0.034 13.8 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltrans_SAM PF10672.4 KEY68487.1 - 0.096 11.5 0.1 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase Glycoamylase PF10091.4 KEY68488.1 - 0.065 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative glucoamylase DUF3133 PF11331.3 KEY68489.1 - 0.027 14.0 6.0 0.23 11.0 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3133) Crust_neurohorm PF01147.12 KEY68489.1 - 0.11 11.8 7.7 0.032 13.5 3.3 1.6 1 1 1 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family zf-A20 PF01754.11 KEY68489.1 - 2.7 7.6 7.2 8.1 6.1 1.5 2.6 2 0 0 2 2 2 0 A20-like zinc finger LrgB PF04172.11 KEY68490.1 - 1.9e-24 86.0 10.3 1.9e-24 86.0 7.2 2.9 2 1 0 2 2 2 1 LrgB-like family LrgA PF03788.9 KEY68490.1 - 1.4e-06 27.9 5.7 1.4e-06 27.9 4.0 3.6 4 1 0 4 4 4 1 LrgA family Linker_histone PF00538.14 KEY68492.1 - 3.2e-24 84.8 0.3 5.9e-24 83.9 0.2 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family Sec23_trunk PF04811.10 KEY68493.1 - 4e-50 170.4 0.0 9.1e-50 169.2 0.0 1.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KEY68493.1 - 1.2e-24 85.7 0.0 2e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KEY68493.1 - 2.6e-17 63.1 0.0 4.2e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KEY68493.1 - 7.1e-17 60.6 4.2 1.5e-16 59.6 2.9 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KEY68493.1 - 1e-06 28.3 0.0 2.3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat DUF2263 PF10021.4 KEY68494.1 - 1.8e-11 44.2 0.0 2.7e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Sulfatase PF00884.18 KEY68495.1 - 3.3e-54 184.1 0.1 4.4e-54 183.7 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KEY68495.1 - 0.08 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KEY68495.1 - 0.23 9.8 0.0 0.35 9.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) HAD_2 PF13419.1 KEY68496.1 - 1.4e-32 113.3 0.1 1.7e-32 113.0 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEY68496.1 - 0.00013 22.4 0.0 0.00024 21.5 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase 2OG-Fe_Oxy_2 PF10014.4 KEY68497.1 - 3.7e-46 156.9 0.1 5.9e-46 156.3 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe dioxygenase DUF2453 PF10507.4 KEY68497.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2453) Glyco_hydro_65C PF03633.10 KEY68498.1 - 0.0026 17.8 0.0 0.0068 16.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain Sporozoite_P67 PF05642.6 KEY68498.1 - 0.083 10.7 0.0 0.11 10.3 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ABC_tran PF00005.22 KEY68499.1 - 1.6e-46 158.0 0.4 6.9e-25 87.9 0.0 3.1 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 KEY68499.1 - 2e-32 112.6 19.4 1.5e-24 86.8 4.2 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KEY68499.1 - 1.3e-10 40.8 0.8 0.011 15.0 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEY68499.1 - 4e-08 33.5 1.1 0.0033 17.4 0.0 4.2 3 1 0 4 4 4 1 AAA domain AAA_29 PF13555.1 KEY68499.1 - 1.2e-07 31.0 0.3 0.0069 15.8 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KEY68499.1 - 2.3e-07 30.4 0.0 0.011 15.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KEY68499.1 - 2.5e-06 26.7 0.0 0.007 15.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KEY68499.1 - 3.8e-06 27.7 0.2 0.13 13.0 0.1 3.4 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KEY68499.1 - 7.6e-06 26.0 0.3 0.084 13.0 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KEY68499.1 - 1.3e-05 25.2 0.1 0.1 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 KEY68499.1 - 1.7e-05 24.4 2.4 0.0077 15.6 0.0 2.9 2 1 0 2 2 2 2 AAA-like domain Miro PF08477.8 KEY68499.1 - 3.7e-05 24.2 0.0 0.34 11.4 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 KEY68499.1 - 8.5e-05 22.4 0.0 0.16 11.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 KEY68499.1 - 0.00021 21.6 0.0 0.51 10.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KEY68499.1 - 0.00043 19.4 0.1 0.58 9.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Arch_ATPase PF01637.13 KEY68499.1 - 0.00051 19.8 0.0 0.0073 16.0 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase AAA PF00004.24 KEY68499.1 - 0.0009 19.4 0.0 0.047 13.8 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 KEY68499.1 - 0.0013 18.2 0.1 0.11 11.9 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family T2SE PF00437.15 KEY68499.1 - 0.0015 17.5 0.2 0.64 8.8 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 KEY68499.1 - 0.0017 18.1 0.4 1.1 9.0 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KEY68499.1 - 0.0019 18.3 0.1 0.69 10.1 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_33 PF13671.1 KEY68499.1 - 0.002 18.0 0.0 0.23 11.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KEY68499.1 - 0.0038 17.1 0.1 0.12 12.2 0.0 3.2 4 0 0 4 4 4 1 AAA domain PduV-EutP PF10662.4 KEY68499.1 - 0.0042 16.5 0.8 0.16 11.4 0.0 2.7 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.20 KEY68499.1 - 0.0057 16.1 0.1 3.4 7.0 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 KEY68499.1 - 0.0068 16.7 13.4 0.044 14.0 0.2 3.3 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 KEY68499.1 - 0.0072 16.0 1.5 2 8.1 0.0 3.6 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 KEY68499.1 - 0.022 13.6 0.0 4.9 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.7 KEY68499.1 - 0.023 14.3 0.4 0.99 9.0 0.1 3.0 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 KEY68499.1 - 0.025 14.0 0.8 0.2 11.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 KEY68499.1 - 0.07 12.7 0.1 11 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 KEY68499.1 - 0.079 11.6 0.0 0.17 10.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Adeno_IVa2 PF02456.10 KEY68499.1 - 0.084 11.5 0.1 1.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein DUF87 PF01935.12 KEY68499.1 - 0.084 12.6 7.2 0.2 11.4 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 GTP_EFTU PF00009.22 KEY68499.1 - 0.086 12.2 0.0 3 7.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain IstB_IS21 PF01695.12 KEY68499.1 - 0.099 12.0 0.8 14 5.0 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein Viral_helicase1 PF01443.13 KEY68499.1 - 0.1 12.1 0.1 3.1 7.2 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 KEY68499.1 - 0.12 11.8 0.1 1.1 8.7 0.0 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase NTPase_1 PF03266.10 KEY68499.1 - 0.25 11.0 1.0 3.3 7.4 0.1 2.5 2 0 0 2 2 2 0 NTPase Dynamin_N PF00350.18 KEY68499.1 - 0.35 10.6 6.7 0.24 11.1 0.1 2.6 3 0 0 3 3 2 0 Dynamin family Aldolase_II PF00596.16 KEY68500.1 - 1.7e-42 145.1 0.1 2.3e-42 144.6 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain AMP-binding PF00501.23 KEY68501.1 - 2.6e-73 246.8 0.0 3.3e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEY68501.1 - 9.1e-12 45.7 0.2 4.4e-11 43.5 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Acyl_transf_1 PF00698.16 KEY68502.1 - 2.8e-68 230.6 0.0 6.2e-68 229.4 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 KEY68502.1 - 8.2e-60 202.4 0.0 2.2e-59 201.0 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 KEY68502.1 - 3.6e-57 193.7 0.0 5.6e-57 193.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 KEY68502.1 - 4.8e-53 179.4 0.3 1e-52 178.4 0.2 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KEY68502.1 - 1.4e-40 138.9 0.2 3.4e-40 137.7 0.2 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KEY68502.1 - 1.9e-34 118.0 0.0 4.6e-34 116.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KEY68502.1 - 2e-18 66.1 0.2 2.5e-17 62.6 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KEY68502.1 - 3e-14 53.2 0.0 2.8e-12 46.9 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KEY68502.1 - 1e-12 49.0 0.0 7.6e-12 46.2 0.0 2.6 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KEY68502.1 - 9.6e-12 44.9 0.1 3.8e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.7 KEY68502.1 - 1.1e-07 31.6 0.2 4e-07 29.7 0.1 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.1 KEY68502.1 - 1.3e-07 31.3 0.0 2.3e-06 27.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY68502.1 - 2.6e-06 27.9 0.0 8.3e-06 26.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY68502.1 - 4.1e-05 23.9 0.0 0.0002 21.7 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 KEY68502.1 - 7e-05 23.0 0.0 0.00024 21.3 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KEY68502.1 - 0.013 14.4 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 KEY68502.1 - 0.043 12.9 0.0 0.087 11.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CFEM PF05730.6 KEY68503.1 - 1.3e-10 40.9 9.6 2.6e-10 39.9 6.6 1.5 1 0 0 1 1 1 1 CFEM domain AATase PF07247.7 KEY68506.1 - 2e-13 49.7 0.0 3e-13 49.1 0.0 1.3 1 1 0 1 1 1 1 Alcohol acetyltransferase WES_acyltransf PF03007.11 KEY68506.1 - 0.0031 17.1 0.0 0.0061 16.1 0.0 1.5 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.15 KEY68506.1 - 0.036 12.9 0.0 0.07 11.9 0.0 1.5 1 0 0 1 1 1 0 Condensation domain Fungal_trans_2 PF11951.3 KEY68507.1 - 1.8e-05 23.5 0.1 2.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY68507.1 - 1.9e-05 24.4 9.7 3.7e-05 23.5 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 KEY68509.1 - 6.2e-18 63.9 8.7 1.3e-06 28.0 1.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat PQQ_2 PF13360.1 KEY68509.1 - 0.00099 18.6 6.8 0.0026 17.2 0.3 2.7 1 1 1 3 3 3 2 PQQ-like domain DUF3312 PF11768.3 KEY68509.1 - 0.00099 17.4 0.0 0.0015 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) dCMP_cyt_deam_1 PF00383.17 KEY68510.1 - 7.6e-10 38.3 0.1 1.5e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region ADH_zinc_N PF00107.21 KEY68511.1 - 1.9e-21 75.9 0.5 3.8e-21 75.0 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY68511.1 - 7.8e-20 70.6 1.8 1.5e-19 69.7 1.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 KEY68511.1 - 0.0079 16.7 0.0 0.038 14.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain TrkA_N PF02254.13 KEY68511.1 - 0.061 13.3 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain IRF-2BP1_2 PF11261.3 KEY68511.1 - 0.63 9.5 2.4 0.39 10.2 0.1 1.8 2 0 0 2 2 2 0 Interferon regulatory factor 2-binding protein zinc finger Aldedh PF00171.17 KEY68512.1 - 9e-149 495.7 0.3 1.1e-148 495.4 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KEY68512.1 - 1.1e-05 24.3 0.0 2.5e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KEY68512.1 - 0.0051 16.0 0.0 0.12 11.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) Oxidored_molyb PF00174.14 KEY68513.1 - 1.2e-47 161.5 0.0 1.8e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KEY68513.1 - 3.4e-25 88.1 5.0 5.8e-25 87.4 3.4 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain SLBB PF10531.4 KEY68513.1 - 0.0048 16.7 0.0 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 SLBB domain Evr1_Alr PF04777.8 KEY68516.1 - 3.3e-27 94.2 0.0 4.7e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Proteasome PF00227.21 KEY68517.1 - 5e-46 156.3 0.1 5.8e-46 156.1 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF3072 PF11272.3 KEY68517.1 - 0.083 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) Cyclin PF08613.6 KEY68518.1 - 7.4e-20 71.8 11.0 5.4e-14 52.8 0.3 3.1 3 0 0 3 3 3 2 Cyclin ADC PF06314.6 KEY68519.1 - 3.8e-07 29.6 0.2 7.3e-07 28.7 0.1 1.4 1 1 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Abhydrolase_3 PF07859.8 KEY68521.1 - 4.4e-31 108.1 0.0 6.4e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY68521.1 - 3.1e-05 23.7 0.0 4.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KEY68521.1 - 0.00029 19.6 0.0 0.00094 17.9 0.0 1.7 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.16 KEY68521.1 - 0.0016 17.7 0.0 0.0028 16.8 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 KEY68521.1 - 0.083 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KEY68521.1 - 0.084 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AXE1 PF05448.7 KEY68521.1 - 0.12 10.8 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF1993 PF09351.5 KEY68525.1 - 1.5e-42 145.2 0.0 1.8e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) adh_short PF00106.20 KEY68526.1 - 1.5e-13 50.9 0.4 3.1e-13 49.9 0.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY68526.1 - 2.3e-07 30.6 0.1 9.8e-07 28.6 0.0 2.0 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KEY68526.1 - 6.2e-06 26.1 0.6 8.3e-06 25.7 0.4 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEY68526.1 - 2.6e-05 23.7 0.9 8.8e-05 22.0 0.6 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KEY68526.1 - 0.028 13.6 0.1 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family TraF_2 PF13729.1 KEY68526.1 - 0.035 12.9 0.3 0.05 12.4 0.2 1.2 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Fungal_trans_2 PF11951.3 KEY68527.1 - 7.5e-26 90.6 1.0 1.1e-25 90.1 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY68527.1 - 2.2e-05 24.2 0.9 4.2e-05 23.3 0.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_IclR PF09339.5 KEY68527.1 - 0.086 12.4 1.2 4.5 6.9 0.1 3.6 4 0 0 4 4 4 0 IclR helix-turn-helix domain HET PF06985.6 KEY68528.1 - 1.8e-24 86.4 7.8 7.6e-22 77.9 5.4 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 KEY68529.1 - 1.3e-40 137.6 1.1 8.4e-14 51.6 0.0 4.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEY68529.1 - 1.5e-27 95.4 2.6 1.3e-09 38.3 0.0 5.3 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 KEY68529.1 - 8.5e-26 88.4 3.3 1.3e-05 24.6 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 KEY68529.1 - 4.8e-22 75.8 2.7 0.0097 16.0 0.0 7.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 KEY68529.1 - 1e-21 76.4 6.5 1.4e-08 34.7 0.1 6.3 4 1 1 6 6 6 4 Ankyrin repeats (many copies) Nucleoplasmin PF03066.10 KEY68529.1 - 0.87 9.0 7.6 1.6 8.2 5.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin WSC PF01822.14 KEY68530.1 - 1.2e-54 182.2 64.2 7.9e-17 60.9 7.1 5.4 5 0 0 5 5 5 4 WSC domain PQQ_3 PF13570.1 KEY68530.1 - 0.0025 18.0 3.9 0.044 14.0 0.0 4.4 4 0 0 4 4 4 1 PQQ-like domain CFEM PF05730.6 KEY68531.1 - 4e-09 36.1 8.4 6.1e-09 35.5 5.8 1.3 1 0 0 1 1 1 1 CFEM domain DUF607 PF04678.8 KEY68531.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF607 Guanylate_cyc_2 PF09778.4 KEY68531.1 - 0.08 12.1 0.1 0.08 12.1 0.0 1.7 2 0 0 2 2 2 0 Guanylylate cyclase Baculo_PEP_C PF04513.7 KEY68532.1 - 0.016 15.0 20.9 0.1 12.4 6.3 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IL28A PF15177.1 KEY68532.1 - 0.09 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Interleukin-28A NPV_P10 PF05531.7 KEY68532.1 - 4 7.7 11.3 38 4.6 0.6 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Pec_lyase_C PF00544.14 KEY68533.1 - 9.9e-28 96.9 3.4 1.4e-27 96.5 2.4 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KEY68533.1 - 2.5e-10 40.3 25.5 2.2e-06 27.5 6.8 2.3 1 1 1 2 2 2 2 Right handed beta helix region Glyco_hydro_28 PF00295.12 KEY68533.1 - 0.0041 16.1 0.2 0.0066 15.4 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 KEY68533.1 - 0.008 16.3 0.7 0.008 16.3 0.5 2.3 1 1 2 3 3 3 2 Pectate lyase superfamily protein YrhK PF14145.1 KEY68534.1 - 2.6e-08 33.3 19.4 0.012 15.2 0.4 4.9 3 2 0 3 3 3 3 YrhK-like protein adh_short PF00106.20 KEY68535.1 - 7.2e-24 84.5 1.8 4.6e-23 81.9 1.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY68535.1 - 2.1e-10 40.5 0.6 7.5e-10 38.7 0.4 1.8 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY68535.1 - 3.1e-10 40.2 0.0 4.2e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEY68535.1 - 6e-05 22.5 0.0 7.5e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY68535.1 - 0.00087 19.3 0.2 0.0039 17.2 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KEY68535.1 - 0.017 14.1 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Zn_clus PF00172.13 KEY68536.1 - 4.3e-07 29.7 12.8 7.9e-07 28.8 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KEY68537.1 - 1.3e-06 28.3 0.1 2.5e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KEY68537.1 - 1.9e-05 24.1 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KEY68537.1 - 0.00048 19.0 0.0 0.00088 18.2 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KEY68537.1 - 0.00075 19.5 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 KEY68537.1 - 0.057 13.8 0.3 0.38 11.2 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Amino_oxidase PF01593.19 KEY68538.1 - 8.2e-30 104.2 0.1 3e-21 76.0 0.1 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KEY68538.1 - 2.2e-05 24.3 0.0 6.1e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Herpes_IE1 PF07340.6 KEY68538.1 - 0.068 11.5 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein Pyr_redox_3 PF13738.1 KEY68538.1 - 0.071 13.1 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Zn_clus PF00172.13 KEY68540.1 - 1.8e-05 24.5 8.3 3e-05 23.8 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY68540.1 - 0.0045 15.9 1.1 0.0064 15.3 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain CsbD PF05532.7 KEY68541.1 - 3.1e-22 77.9 18.6 3.7e-12 45.7 0.6 3.9 3 1 0 3 3 3 3 CsbD-like DUF2937 PF11157.3 KEY68541.1 - 0.23 10.7 2.5 0.38 10.0 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) MFS_1 PF07690.11 KEY68542.1 - 3.8e-15 55.4 27.9 3.8e-15 55.4 19.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Gln-synt_C PF00120.19 KEY68544.1 - 2.6e-51 174.2 0.0 3.7e-51 173.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 KEY68544.1 - 1.4e-26 93.7 0.0 3.2e-26 92.5 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase HATPase_c PF02518.21 KEY68545.1 - 1.5e-28 98.7 0.0 3.9e-28 97.3 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KEY68545.1 - 3.4e-27 94.6 0.3 6.4e-27 93.7 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KEY68545.1 - 7.7e-13 48.2 0.0 1.7e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 KEY68545.1 - 4.2e-05 23.6 0.1 0.11 12.6 0.0 3.6 3 0 0 3 3 3 2 HAMP domain Maf1 PF09174.5 KEY68546.1 - 5.7e-52 176.1 0.0 8.6e-52 175.5 0.0 1.3 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.15 KEY68546.1 - 1.9e-50 170.3 0.9 2.8e-50 169.7 0.7 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1220 PF06758.8 KEY68546.1 - 0.079 12.7 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Repeat of unknown function (DUF1220) Aldo_ket_red PF00248.16 KEY68547.1 - 2.1e-10 39.9 0.0 2.8e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Kdo PF06293.9 KEY68548.1 - 1.3e-06 27.6 0.0 6.2e-06 25.4 0.0 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KEY68548.1 - 1.4e-06 27.6 0.0 1.8e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KEY68548.1 - 2e-06 27.7 1.1 0.002 17.8 0.4 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 KEY68548.1 - 0.0013 18.0 0.0 0.0028 17.0 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 KEY68548.1 - 0.0088 15.1 0.0 0.016 14.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase CMD PF02627.15 KEY68551.1 - 2e-08 33.9 0.1 1.4e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family SPT16 PF08644.6 KEY68552.1 - 1.2e-57 193.9 0.1 1.2e-57 193.9 0.1 2.5 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 KEY68552.1 - 1.4e-52 177.5 0.2 1.4e-52 177.5 0.1 1.9 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.7 KEY68552.1 - 9.8e-23 79.9 0.2 2.6e-22 78.6 0.1 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.19 KEY68552.1 - 1.3e-22 80.4 0.0 2.3e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 CDC50 PF03381.10 KEY68553.1 - 3.2e-98 328.3 0.0 4e-98 328.0 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family MUG113 PF13455.1 KEY68554.1 - 2.5e-10 40.6 0.4 1.2e-09 38.5 0.1 2.3 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 KEY68554.1 - 1.2e-09 38.4 0.2 4.5e-09 36.6 0.1 2.0 1 0 0 1 1 1 1 T5orf172 domain FLO_LFY PF01698.11 KEY68554.1 - 9 5.0 7.3 2.8 6.7 0.1 2.5 3 0 0 3 3 3 0 Floricaula / Leafy protein Transthyretin PF00576.16 KEY68556.1 - 2.1e-25 88.7 0.2 1.2e-15 57.3 0.2 2.0 1 1 1 2 2 2 2 HIUase/Transthyretin family Adenylsucc_synt PF00709.16 KEY68557.1 - 2.4e-134 448.1 0.0 1.2e-76 258.0 0.0 2.0 2 0 0 2 2 2 2 Adenylosuccinate synthetase ArsA_ATPase PF02374.10 KEY68558.1 - 1.1e-110 369.4 0.1 1.3e-110 369.2 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 KEY68558.1 - 3.9e-17 62.2 0.1 7e-17 61.4 0.1 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KEY68558.1 - 2.1e-08 34.2 0.0 2.1e-07 30.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 KEY68558.1 - 3.6e-06 26.3 0.0 1e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 KEY68558.1 - 0.00019 20.9 0.0 0.0022 17.4 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 KEY68558.1 - 0.0027 17.4 0.4 0.014 15.0 0.2 2.3 2 1 1 3 3 3 1 Part of AAA domain AAA_25 PF13481.1 KEY68558.1 - 0.0079 15.6 0.1 0.015 14.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KEY68558.1 - 0.015 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein MipZ PF09140.6 KEY68558.1 - 0.019 14.0 0.1 0.038 13.0 0.0 1.5 1 1 0 1 1 1 0 ATPase MipZ AAA_10 PF12846.2 KEY68558.1 - 0.022 14.2 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain YhjQ PF06564.7 KEY68558.1 - 0.025 13.9 0.0 0.065 12.5 0.0 1.7 1 0 0 1 1 1 0 YhjQ protein NB-ARC PF00931.17 KEY68558.1 - 0.047 12.5 0.0 0.076 11.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 KEY68558.1 - 0.087 13.1 0.1 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain DWNN PF08783.6 KEY68559.1 - 1.3e-27 95.5 0.0 2.5e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-RING_6 PF14835.1 KEY68559.1 - 0.00035 20.2 1.5 0.00065 19.4 1.0 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-CCHC_2 PF13696.1 KEY68559.1 - 0.00047 19.5 4.0 0.0015 17.9 2.8 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KEY68559.1 - 0.0041 16.9 1.5 0.0041 16.9 1.0 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-RING_4 PF14570.1 KEY68559.1 - 0.0044 16.5 4.3 0.0097 15.4 3.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 KEY68559.1 - 0.015 14.9 7.1 0.015 14.9 4.9 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-CCHC_3 PF13917.1 KEY68559.1 - 0.047 13.4 0.1 0.14 11.9 0.1 1.8 1 0 0 1 1 1 0 Zinc knuckle FYVE_2 PF02318.11 KEY68559.1 - 0.27 11.1 2.9 0.7 9.8 2.0 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4_4 PF15227.1 KEY68559.1 - 0.58 10.0 8.5 1.8 8.5 5.9 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KEY68559.1 - 0.66 9.6 8.7 1.3 8.7 6.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEY68559.1 - 1.4 8.9 13.6 0.072 13.1 5.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEY68559.1 - 2 8.3 12.0 0.045 13.5 3.8 1.6 2 0 0 2 2 2 0 Ring finger domain FTHFS PF01268.14 KEY68560.1 - 7.8e-257 852.7 2.6 8.6e-257 852.5 0.3 1.8 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 KEY68560.1 - 2e-68 228.5 0.8 2e-68 228.5 0.6 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KEY68560.1 - 2.7e-29 101.5 0.0 5.4e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Peptidase_M20 PF01546.23 KEY68561.1 - 2e-32 112.2 0.0 3.3e-32 111.5 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KEY68561.1 - 5e-13 48.7 0.0 8.5e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Yippee-Mis18 PF03226.9 KEY68562.1 - 3.7e-22 78.1 0.2 5.2e-22 77.6 0.1 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 KEY68562.1 - 3.4e-05 23.7 0.7 7.6e-05 22.5 0.5 1.6 1 1 0 1 1 1 1 C-terminal domain of RIG-I zf-CHY PF05495.7 KEY68562.1 - 0.022 14.8 0.1 3.1 8.0 0.0 2.3 2 0 0 2 2 2 0 CHY zinc finger Trehalase PF01204.13 KEY68563.1 - 8.2e-189 628.4 0.0 9.7e-189 628.2 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 KEY68563.1 - 2.5e-17 61.8 0.3 4.2e-17 61.1 0.2 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ICL PF00463.16 KEY68564.1 - 4.8e-280 929.1 0.0 5.5e-280 929.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KEY68564.1 - 2.5e-12 46.5 0.0 4.3e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Pkinase PF00069.20 KEY68565.1 - 3.7e-74 249.1 0.0 5.2e-74 248.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY68565.1 - 6.1e-37 127.0 0.0 8.6e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 KEY68565.1 - 5.3e-17 61.7 0.2 1.3e-16 60.5 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 KEY68565.1 - 5e-08 32.2 0.0 2.3e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KEY68565.1 - 0.00027 20.3 0.2 0.00048 19.5 0.2 1.3 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 KEY68565.1 - 0.0014 17.2 0.1 0.0026 16.4 0.1 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 KEY68565.1 - 0.062 13.0 0.8 0.43 10.2 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Peptidase_C14 PF00656.17 KEY68566.1 - 6.9e-70 235.5 0.6 1.1e-69 234.8 0.0 1.6 2 0 0 2 2 2 1 Caspase domain WW PF00397.21 KEY68567.1 - 8e-07 28.8 3.9 2.4e-06 27.3 2.7 1.9 1 0 0 1 1 1 1 WW domain TPR_2 PF07719.12 KEY68567.1 - 0.032 14.1 7.3 0.31 11.0 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4398 PF14346.1 KEY68567.1 - 0.032 14.2 6.6 0.052 13.5 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) DUF2076 PF09849.4 KEY68567.1 - 1.8 8.5 20.5 0.2 11.7 11.0 2.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) TPR_1 PF00515.23 KEY68567.1 - 7.1 6.4 8.6 0.29 10.8 0.7 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Epimerase PF01370.16 KEY68568.1 - 4.5e-12 45.9 0.2 9.6e-12 44.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KEY68568.1 - 1.6e-06 27.2 0.1 2.9e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KEY68568.1 - 8.8e-06 25.8 0.1 9.3e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEY68568.1 - 4.3e-05 22.3 0.5 0.001 17.8 0.3 2.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KEY68568.1 - 0.00015 21.7 0.6 0.00042 20.2 0.4 1.8 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 KEY68568.1 - 0.00016 21.0 0.3 0.00029 20.1 0.2 1.5 1 1 0 1 1 1 1 NmrA-like family KR PF08659.5 KEY68568.1 - 0.00018 21.1 0.2 0.00029 20.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Cutinase PF01083.17 KEY68569.1 - 7.6e-48 162.5 10.0 1e-47 162.2 6.9 1.1 1 0 0 1 1 1 1 Cutinase CBM_1 PF00734.13 KEY68569.1 - 2.1e-08 33.7 17.2 2.1e-08 33.7 11.9 4.7 5 1 0 5 5 5 1 Fungal cellulose binding domain PE-PPE PF08237.6 KEY68569.1 - 2.2e-05 23.9 0.1 3.5e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.2 KEY68569.1 - 5.1e-05 23.2 0.1 6.5e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY68569.1 - 0.021 14.3 0.1 0.037 13.5 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY68569.1 - 0.027 14.2 0.2 0.037 13.7 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Acetyltransf_10 PF13673.1 KEY68570.1 - 2.2e-06 27.7 0.0 3.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEY68570.1 - 6.6e-06 26.0 0.0 1.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEY68570.1 - 2e-05 24.6 0.0 3.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4381 PF14316.1 KEY68571.1 - 0.056 13.5 0.6 0.14 12.2 0.1 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) PsbI PF02532.9 KEY68571.1 - 3.2 7.4 5.0 2.2 7.9 0.4 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Tail_P2_I PF09684.5 KEY68572.1 - 0.033 13.7 0.4 1 8.9 0.1 2.4 2 0 0 2 2 2 0 Phage tail protein (Tail_P2_I) T2SF PF00482.18 KEY68572.1 - 0.064 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F FlgN PF05130.7 KEY68573.1 - 0.12 12.6 2.2 0.15 12.3 1.5 1.2 1 0 0 1 1 1 0 FlgN protein TEX13 PF15186.1 KEY68573.1 - 0.24 10.9 3.1 0.29 10.6 2.1 1.1 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DUF1620 PF07774.8 KEY68575.1 - 4.8e-68 228.6 0.0 7.4e-68 228.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 KEY68575.1 - 2.7e-13 49.9 7.4 1.3e-11 44.4 0.9 2.9 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 KEY68575.1 - 0.00034 19.9 2.2 0.46 10.1 0.0 4.4 6 0 0 6 6 6 2 PQQ enzyme repeat CBM_19 PF03427.8 KEY68576.1 - 0.54 10.0 8.5 0.89 9.3 5.9 1.5 1 1 0 1 1 1 0 Carbohydrate binding domain (family 19) Metallophos PF00149.23 KEY68577.1 - 0.0001 21.7 3.7 0.00033 20.0 2.6 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF914 PF06027.7 KEY68578.1 - 1.7e-107 359.1 15.6 2.3e-107 358.7 10.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 KEY68578.1 - 1.4e-07 31.6 32.0 4e-05 23.6 8.0 2.5 2 1 1 3 3 3 2 EamA-like transporter family Ninjurin PF04923.7 KEY68578.1 - 0.048 13.3 0.1 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 Ninjurin TPT PF03151.11 KEY68578.1 - 0.083 12.5 25.4 0.1 12.2 2.4 2.9 3 0 0 3 3 3 0 Triose-phosphate Transporter family FTA2 PF13095.1 KEY68579.1 - 7.8e-18 64.8 0.0 1.3e-17 64.0 0.0 1.5 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 ERM PF00769.14 KEY68582.1 - 0.14 11.7 6.1 0.21 11.1 4.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Menin PF05053.8 KEY68582.1 - 4.9 5.1 7.3 8.5 4.4 5.0 1.3 1 0 0 1 1 1 0 Menin DHQ_synthase PF01761.15 KEY68583.1 - 1.1e-52 178.5 0.0 1.7e-52 177.9 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 KEY68583.1 - 1.6e-12 47.2 0.0 2.3e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Methyltransf_3 PF01596.12 KEY68584.1 - 2.5e-14 52.8 0.0 3.6e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 KEY68584.1 - 9.9e-11 42.4 0.0 1.6e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.6 KEY68584.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase CmcI PF04989.7 KEY68584.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase ATP-grasp_4 PF13535.1 KEY68585.1 - 1.5e-11 44.3 0.0 2.7e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KEY68585.1 - 1.6e-10 40.3 0.0 5.1e-10 38.6 0.0 1.8 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon AhpC-TSA_2 PF13911.1 KEY68586.1 - 6.6e-13 48.5 0.1 1e-12 47.9 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KEY68586.1 - 0.0013 18.3 0.0 0.0027 17.3 0.0 1.4 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 KEY68586.1 - 0.005 16.3 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 Redoxin PAP_assoc PF03828.14 KEY68587.1 - 2.8e-16 59.2 0.2 6.1e-16 58.1 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KEY68587.1 - 1.2e-05 25.5 0.0 2.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PALP PF00291.20 KEY68590.1 - 3.1e-64 217.1 0.2 3.8e-64 216.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KEY68590.1 - 0.036 13.0 0.1 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family ADH_N PF08240.7 KEY68591.1 - 8.4e-21 73.7 4.5 1.5e-20 72.9 3.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY68591.1 - 4.1e-11 42.5 0.1 2.7e-10 39.8 0.1 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KEY68591.1 - 0.00017 20.7 0.0 0.00032 19.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KEY68591.1 - 0.0044 16.6 0.1 0.0083 15.7 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 KEY68591.1 - 0.015 15.0 0.1 0.024 14.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 KEY68591.1 - 0.074 12.8 0.9 0.14 11.9 0.6 1.4 1 0 0 1 1 1 0 ThiF family ELFV_dehydrog PF00208.16 KEY68591.1 - 0.13 11.7 0.1 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Saccharop_dh PF03435.13 KEY68592.1 - 2e-127 425.3 0.0 2.3e-127 425.1 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KEY68592.1 - 2.7e-06 27.5 0.1 4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 KEY68592.1 - 5.7e-05 23.2 0.1 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 KEY68592.1 - 0.0046 16.3 0.1 0.045 13.1 0.0 2.4 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain GFO_IDH_MocA PF01408.17 KEY68592.1 - 0.024 15.1 0.0 0.043 14.3 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.13 KEY68592.1 - 0.11 12.4 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Rhodanese PF00581.15 KEY68594.1 - 5.1e-06 26.8 0.0 1e-05 25.8 0.0 1.6 1 1 0 1 1 1 1 Rhodanese-like domain bZIP_1 PF00170.16 KEY68595.1 - 0.007 16.2 8.8 0.017 15.0 4.5 2.3 1 1 1 2 2 2 1 bZIP transcription factor FMN_red PF03358.10 KEY68596.1 - 1.3e-24 86.4 0.0 3.4e-24 85.0 0.0 1.7 2 0 0 2 2 2 1 NADPH-dependent FMN reductase MFS_1 PF07690.11 KEY68597.1 - 1.4e-22 79.9 47.5 8.5e-12 44.4 14.2 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY68597.1 - 6e-06 25.1 6.7 6e-06 25.1 4.6 3.2 2 1 1 3 3 3 3 Sugar (and other) transporter DUF2178 PF09946.4 KEY68597.1 - 0.32 10.7 8.4 0.048 13.3 0.8 2.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2178) Pkinase PF00069.20 KEY68598.1 - 7.3e-21 74.4 0.0 2.1e-20 72.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY68598.1 - 2.3e-09 36.7 0.2 0.00072 18.7 0.0 3.5 3 2 1 4 4 4 2 Protein tyrosine kinase Kinase-like PF14531.1 KEY68598.1 - 0.00085 18.3 0.1 0.042 12.8 0.0 2.8 3 0 0 3 3 3 1 Kinase-like Methyltransf_11 PF08241.7 KEY68599.1 - 5.1e-10 39.6 0.0 8.3e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY68599.1 - 6.3e-10 38.5 0.0 9.4e-10 37.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 KEY68599.1 - 2e-08 34.1 0.0 3.1e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY68599.1 - 8.3e-07 28.7 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY68599.1 - 8.6e-07 29.3 0.0 1.4e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY68599.1 - 5.7e-05 23.4 0.0 0.0001 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY68599.1 - 0.0017 18.3 0.0 0.0079 16.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY68599.1 - 0.0086 16.6 0.0 0.017 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Adeno_E4 PF05385.6 KEY68599.1 - 0.16 11.9 0.1 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 Mastadenovirus early E4 13 kDa protein Acyl_transf_1 PF00698.16 KEY68600.1 - 1.6e-69 234.6 0.0 2.5e-69 234.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 KEY68600.1 - 3e-64 216.9 0.3 7.6e-64 215.6 0.1 1.9 2 0 0 2 2 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KEY68600.1 - 5.9e-58 195.5 0.1 2.6e-57 193.4 0.1 2.2 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 KEY68600.1 - 1.3e-52 178.8 0.0 2e-52 178.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KEY68600.1 - 5.6e-45 153.2 0.3 2.5e-44 151.1 0.0 2.4 3 0 0 3 3 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KEY68600.1 - 4.1e-32 110.5 0.0 1.5e-31 108.7 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KEY68600.1 - 1.7e-19 70.0 0.0 4e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KEY68600.1 - 6.2e-16 58.1 0.1 3e-15 55.9 0.1 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 KEY68600.1 - 3.7e-12 46.0 0.0 1.2e-11 44.4 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KEY68600.1 - 4e-09 37.4 0.0 2.6e-08 34.8 0.0 2.4 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KEY68600.1 - 4.4e-09 36.2 0.2 3.4e-08 33.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY68600.1 - 2e-08 34.7 0.0 7.9e-08 32.8 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY68600.1 - 2.5e-07 31.1 0.0 6.9e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 KEY68600.1 - 4.1e-06 26.5 0.0 1.2e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 KEY68600.1 - 1.4e-05 24.3 0.0 3.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEY68600.1 - 0.00011 22.4 0.0 0.0032 17.8 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 KEY68600.1 - 0.0012 19.0 0.1 0.0037 17.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.4 KEY68600.1 - 0.0018 17.7 0.0 0.035 13.5 0.0 2.5 2 1 0 2 2 2 1 Putative methyltransferase Thiolase_N PF00108.18 KEY68600.1 - 0.011 14.7 0.2 0.025 13.5 0.2 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain DUF938 PF06080.7 KEY68600.1 - 0.016 14.7 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_28 PF02636.12 KEY68600.1 - 0.15 11.4 0.0 0.35 10.2 0.0 1.6 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.7 KEY68600.1 - 0.17 10.7 0.0 0.35 9.6 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Thioesterase PF00975.15 KEY68601.1 - 5.2e-16 59.5 0.0 5.9e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 KEY68601.1 - 4.5e-05 23.4 0.0 4.8e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY68601.1 - 0.012 15.4 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KEY68601.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KEY68601.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase p450 PF00067.17 KEY68602.1 - 7.6e-48 163.1 0.1 1e-47 162.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Vps26 PF03643.10 KEY68602.1 - 0.059 12.1 0.0 0.12 11.1 0.0 1.5 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 Pyr_redox_3 PF13738.1 KEY68603.1 - 8.9e-19 68.3 0.0 1.9e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY68603.1 - 3.8e-09 36.4 0.0 1.3e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 KEY68603.1 - 4.2e-09 35.1 0.1 1.3e-08 33.4 0.1 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KEY68603.1 - 2.4e-05 24.3 0.0 0.00029 20.7 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEY68603.1 - 7.2e-05 21.8 0.0 0.00038 19.4 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KEY68603.1 - 0.00044 20.0 0.0 0.26 11.0 0.0 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 KEY68603.1 - 0.001 19.1 0.0 0.83 9.7 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 KEY68603.1 - 0.013 14.3 0.0 2.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.22 KEY68603.1 - 0.023 15.0 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEY68603.1 - 0.12 11.2 0.0 3.2 6.5 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 KEY68603.1 - 0.17 10.9 0.0 1.7 7.6 0.0 2.3 2 1 1 3 3 3 0 Thi4 family MFS_1 PF07690.11 KEY68604.1 - 9.5e-33 113.3 38.1 9.5e-33 113.3 26.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily SnoaL_2 PF12680.2 KEY68605.1 - 1.3e-05 25.5 0.1 1.8e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain PAF-AH_p_II PF03403.8 KEY68607.1 - 5.3e-31 107.2 0.0 7.7e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KEY68607.1 - 2.3e-11 43.6 0.1 4.4e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY68607.1 - 1.6e-06 28.1 1.0 1.6e-06 28.1 0.7 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KEY68607.1 - 3.9e-05 22.6 0.0 0.052 12.4 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 KEY68607.1 - 0.025 14.1 0.2 0.13 11.7 0.0 2.1 2 1 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KEY68607.1 - 0.063 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Chlorophyllase PF07224.6 KEY68607.1 - 0.066 11.9 0.0 0.48 9.1 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase Peptidase_S8 PF00082.17 KEY68609.1 - 1.6e-54 184.9 9.8 2.4e-54 184.4 6.8 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KEY68609.1 - 8.3e-21 74.3 0.5 1.8e-20 73.2 0.3 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Beach PF02138.13 KEY68610.1 - 1.1e-110 369.3 0.0 2.2e-110 368.3 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 KEY68610.1 - 5.3e-13 48.7 0.1 5.3e-13 48.7 0.1 2.1 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 KEY68610.1 - 1.4e-10 41.5 0.0 3.2e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 KEY68610.1 - 9.7e-09 34.7 1.6 0.0049 16.7 0.0 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Laminin_G_2 PF02210.19 KEY68610.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Laminin G domain DDOST_48kD PF03345.9 KEY68612.1 - 2.5e-155 517.1 0.0 2.8e-155 517.0 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF2892 PF11127.3 KEY68612.1 - 0.4 10.5 2.2 0.3 10.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) Isy1 PF06246.7 KEY68613.1 - 2.3e-87 292.6 0.1 3.1e-87 292.1 0.1 1.2 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.5 KEY68613.1 - 0.021 14.6 0.1 0.08 12.8 0.0 1.8 2 0 0 2 2 2 0 YolD-like protein CorA PF01544.13 KEY68615.1 - 8.6e-11 41.4 0.9 2.3e-10 39.9 0.6 1.7 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Aa_trans PF01490.13 KEY68616.1 - 4.1e-25 88.1 28.0 5.3e-25 87.7 19.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3040 PF11239.3 KEY68616.1 - 3.9 7.5 7.2 7.2 6.7 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) adh_short PF00106.20 KEY68617.1 - 1.3e-25 90.2 1.7 1.6e-25 89.9 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY68617.1 - 4.8e-17 62.5 0.0 5.8e-17 62.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY68617.1 - 3.3e-09 36.6 0.4 5.1e-09 36.0 0.3 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KEY68617.1 - 7.8e-05 22.3 0.1 0.00014 21.6 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KEY68617.1 - 0.015 14.3 0.1 0.036 13.1 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 KEY68617.1 - 0.033 13.6 0.1 0.053 12.9 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KEY68617.1 - 0.09 12.5 0.8 0.37 10.6 0.2 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_18 PF12847.2 KEY68617.1 - 0.12 12.9 0.0 0.52 10.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 KEY68617.1 - 0.13 12.7 0.0 0.3 11.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Ribosomal_S28e PF01200.13 KEY68618.1 - 4.4e-34 116.0 1.7 4.8e-34 115.9 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e IBR PF01485.16 KEY68619.1 - 1.3e-06 28.1 24.1 0.00058 19.6 1.4 3.7 3 1 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 KEY68619.1 - 0.19 11.7 34.2 0.053 13.5 3.4 3.9 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KEY68619.1 - 8.7 6.3 27.9 0.033 14.0 1.8 4.3 3 1 1 4 4 4 0 zinc finger of C3HC4-type, RING TFIIA PF03153.8 KEY68620.1 - 0.81 9.5 8.8 1 9.2 6.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pol_alpha_B_N PF08418.5 KEY68620.1 - 8.4 5.8 15.2 12 5.3 10.5 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal RCR PF12273.3 KEY68622.1 - 1 9.8 4.9 2 9.0 3.4 1.7 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Sugar_tr PF00083.19 KEY68623.1 - 4.9e-122 407.7 25.5 5.6e-122 407.5 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY68623.1 - 5e-20 71.5 52.0 3.2e-19 68.8 20.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 KEY68623.1 - 0.0015 17.3 1.5 0.049 12.3 0.1 2.3 2 0 0 2 2 2 2 BT1 family G-alpha PF00503.15 KEY68626.1 - 4.3e-30 104.6 0.0 5.7e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit EAF PF09816.4 KEY68628.1 - 5.3e-17 61.7 0.0 1.4e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor GFA PF04828.9 KEY68629.1 - 3.5e-09 36.4 0.1 5e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme POP1 PF06978.6 KEY68630.1 - 6.9e-62 208.4 10.3 1.5e-61 207.3 7.1 1.6 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 KEY68630.1 - 1e-27 95.8 0.2 2.2e-27 94.7 0.1 1.6 1 0 0 1 1 1 1 POPLD (NUC188) domain NT-C2 PF10358.4 KEY68631.1 - 2.6e-26 91.8 0.0 3.8e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins HSP70 PF00012.15 KEY68632.1 - 4.8e-79 265.8 5.5 7.3e-79 265.2 3.8 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KEY68632.1 - 6e-06 25.0 0.3 1e-05 24.2 0.2 1.5 1 1 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.13 KEY68632.1 - 0.00094 18.3 0.2 0.045 12.8 0.1 2.6 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase BRAP2 PF07576.7 KEY68632.1 - 0.024 14.2 0.1 0.05 13.1 0.1 1.5 1 0 0 1 1 1 0 BRCA1-associated protein 2 FtsA PF14450.1 KEY68632.1 - 0.71 9.7 5.1 6.5 6.6 0.1 3.1 3 1 0 3 3 3 0 Cell division protein FtsA Myc_N PF01056.13 KEY68632.1 - 0.74 8.9 4.4 0.25 10.4 0.7 1.8 2 0 0 2 2 2 0 Myc amino-terminal region zf-C2H2_4 PF13894.1 KEY68634.1 - 7.4e-07 29.0 5.8 0.0048 17.1 1.0 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY68634.1 - 0.00034 20.7 16.0 0.021 15.1 1.9 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KEY68634.1 - 1.1 9.6 21.2 0.098 12.9 2.2 3.5 3 0 0 3 3 3 0 Zinc-finger double domain AAA_12 PF13087.1 KEY68635.1 - 1.6e-22 79.8 0.0 5e-21 75.0 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 KEY68635.1 - 2.1e-13 50.4 0.0 3.9e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 KEY68635.1 - 1.4e-07 31.5 0.0 3.6e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 KEY68635.1 - 0.00021 20.8 0.0 0.051 13.0 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 KEY68635.1 - 0.16 11.7 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain DNA_methylase PF00145.12 KEY68636.1 - 1.3e-40 139.5 0.0 1.6e-28 99.7 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase Cons_hypoth95 PF03602.10 KEY68636.1 - 0.051 12.9 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 SEN1_N PF12726.2 KEY68637.1 - 1.4e-123 413.4 0.2 1.8e-123 413.1 0.2 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 KEY68637.1 - 1.3e-70 237.6 2.3 1.3e-70 237.6 1.6 2.3 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KEY68637.1 - 1.4e-62 210.6 0.0 2.5e-62 209.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEY68637.1 - 1.4e-11 43.9 2.3 1.8e-10 40.4 0.3 3.3 2 1 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KEY68637.1 - 1.3e-07 31.4 2.4 9.4e-05 22.0 1.1 3.2 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 KEY68637.1 - 8.9e-05 22.1 0.0 0.17 11.3 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 KEY68637.1 - 0.00055 19.3 11.5 0.0017 17.7 2.3 3.6 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 KEY68637.1 - 0.031 14.4 0.3 0.9 9.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 KEY68637.1 - 0.2 11.9 7.6 0.13 12.5 0.2 2.8 2 0 0 2 2 2 0 AAA domain Sporozoite_P67 PF05642.6 KEY68638.1 - 0.49 8.1 3.5 0.54 8.0 2.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen adh_short PF00106.20 KEY68640.1 - 2.3e-08 34.1 1.3 2.5e-07 30.7 0.4 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY68640.1 - 0.00014 21.6 0.1 0.00024 20.8 0.1 1.4 1 0 0 1 1 1 1 KR domain PTCB-BRCT PF12738.2 KEY68641.1 - 5e-12 45.5 0.0 1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KEY68641.1 - 8e-12 45.1 0.0 1.5e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 KEY68641.1 - 9.2e-05 22.5 0.0 0.00029 20.9 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain TFIIF_alpha PF05793.7 KEY68641.1 - 6.6 4.9 21.7 9.2 4.5 15.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) eIF-1a PF01176.14 KEY68643.1 - 1.2e-27 95.1 0.1 1.7e-27 94.6 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 WH1 PF00568.18 KEY68644.1 - 3.3e-25 87.9 0.1 4.7e-25 87.4 0.1 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 KEY68644.1 - 7.1e-06 25.4 0.3 1.9e-05 24.1 0.2 1.7 1 0 0 1 1 1 1 WH2 motif TBX PF12598.3 KEY68645.1 - 0.017 15.4 0.9 0.02 15.2 0.6 1.1 1 0 0 1 1 1 0 T-box transcription factor ERCC4 PF02732.10 KEY68646.1 - 7.4e-27 93.8 0.1 3.9e-26 91.5 0.0 2.2 2 0 0 2 2 2 1 ERCC4 domain Glycoprotein_B PF00606.13 KEY68647.1 - 0.088 10.8 3.0 0.091 10.7 2.0 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B Coiled PF05710.7 KEY68647.1 - 0.12 12.9 1.0 0.18 12.2 0.7 1.3 1 0 0 1 1 1 0 Coiled coil CorA PF01544.13 KEY68648.1 - 3.3e-16 59.1 0.8 5.3e-16 58.5 0.5 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Cyclin PF08613.6 KEY68650.1 - 5e-14 52.9 0.5 2.2e-13 50.8 0.0 2.2 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 KEY68650.1 - 0.02 14.4 0.0 0.072 12.6 0.0 1.9 2 0 0 2 2 2 0 Cyclin, N-terminal domain DEAD PF00270.24 KEY68651.1 - 1.3e-35 122.3 0.0 2.2e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY68651.1 - 3.4e-23 81.3 0.1 1.3e-22 79.4 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEY68651.1 - 3.4e-05 23.7 0.0 8.7e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Rpr2 PF04032.11 KEY68652.1 - 4.3e-22 77.7 0.1 6.2e-22 77.2 0.1 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-BED PF02892.10 KEY68652.1 - 0.0019 17.9 0.8 1.8 8.3 0.1 2.3 2 0 0 2 2 2 2 BED zinc finger DASH_Hsk3 PF08227.6 KEY68653.1 - 4.6e-22 77.9 4.7 7.2e-22 77.3 3.3 1.3 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like MRP-L28 PF09812.4 KEY68653.1 - 0.076 12.8 0.0 0.086 12.6 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 ApbA PF02558.11 KEY68654.1 - 7.8e-24 83.8 0.0 1.1e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KEY68654.1 - 1.2e-20 73.7 0.0 1.8e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal OPT PF03169.10 KEY68656.1 - 3.9e-181 603.6 53.3 4.4e-181 603.4 37.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein EIAV_GP90 PF00971.13 KEY68656.1 - 0.18 10.2 1.1 0.24 9.8 0.1 1.6 2 0 0 2 2 2 0 EIAV coat protein, gp90 Ribosomal_L37e PF01907.14 KEY68657.1 - 5.1e-27 93.4 10.2 8.4e-27 92.7 7.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 KEY68657.1 - 0.0034 17.1 1.4 0.0054 16.5 1.0 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 KEY68657.1 - 0.041 13.5 0.5 0.052 13.2 0.3 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-C4pol PF14260.1 KEY68657.1 - 0.046 13.7 0.9 0.071 13.1 0.6 1.4 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta zf-ribbon_3 PF13248.1 KEY68657.1 - 0.083 12.1 1.2 0.16 11.1 0.8 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KEY68657.1 - 0.21 11.1 2.3 8.8 5.9 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_6 PF14599.1 KEY68657.1 - 0.34 10.7 2.3 0.54 10.0 1.6 1.3 1 0 0 1 1 1 0 Zinc-ribbon GFA PF04828.9 KEY68657.1 - 0.75 9.7 4.5 14 5.6 3.0 2.2 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zf-C3HC4 PF00097.20 KEY68657.1 - 4.2 7.1 6.4 6.8 6.4 4.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RNA_POL_M_15KD PF02150.11 KEY68657.1 - 6.2 6.6 5.5 3.7 7.3 0.3 2.3 1 1 1 2 2 2 0 RNA polymerases M/15 Kd subunit Ribosomal_S14 PF00253.16 KEY68657.1 - 9.8 5.6 12.3 2.7 7.4 0.1 2.8 2 1 1 3 3 3 0 Ribosomal protein S14p/S29e DUF2348 PF09807.4 KEY68658.1 - 5.3e-10 38.8 0.1 8.6e-10 38.1 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) KaiC PF06745.8 KEY68658.1 - 1.2e-08 34.3 0.0 1.5e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 KaiC Thioredoxin PF00085.15 KEY68659.1 - 4.8e-08 32.6 0.0 7.6e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KEY68659.1 - 0.027 14.6 0.0 0.24 11.5 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KEY68659.1 - 0.037 14.0 0.0 0.082 12.9 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like Sel1 PF08238.7 KEY68660.1 - 3.3e-45 151.5 19.9 1.5e-07 31.7 0.1 8.0 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.1 KEY68660.1 - 0.0029 17.9 4.3 2.6 8.7 0.0 5.9 5 1 0 5 5 5 1 Tetratricopeptide repeat CBP4 PF07960.6 KEY68662.1 - 9.7e-34 115.7 1.2 1.3e-33 115.3 0.8 1.1 1 0 0 1 1 1 1 CBP4 DUF3103 PF11301.3 KEY68662.1 - 0.035 12.8 0.0 0.038 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) Seryl_tRNA_N PF02403.17 KEY68662.1 - 1.7 8.6 6.3 3.9 7.5 4.3 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain NAC PF01849.13 KEY68663.1 - 2.1e-21 75.1 0.6 3.4e-21 74.5 0.2 1.5 2 0 0 2 2 2 1 NAC domain A_deamin PF02137.13 KEY68664.1 - 7.6e-61 206.3 0.0 8.9e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Ribosomal_L24e PF01246.15 KEY68665.1 - 6.5e-31 106.0 0.3 6.5e-31 106.0 0.2 1.9 2 1 0 2 2 2 1 Ribosomal protein L24e Redoxin PF08534.5 KEY68666.1 - 3.7e-34 117.3 0.4 4.2e-34 117.1 0.3 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KEY68666.1 - 6.6e-16 58.1 0.2 8.4e-16 57.7 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1348 PF07080.6 KEY68667.1 - 1.2e-59 200.2 9.2 1.4e-59 199.9 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 KEY68667.1 - 4.2e-07 30.3 2.0 6.3e-07 29.7 1.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KEY68667.1 - 1.7e-06 28.1 0.4 2.8e-06 27.4 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.7 KEY68667.1 - 0.059 12.9 0.1 0.087 12.4 0.1 1.4 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase RGS PF00615.14 KEY68669.1 - 7.9e-05 22.7 0.1 0.0093 16.0 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF3291 PF11695.3 KEY68669.1 - 0.0074 15.7 0.0 0.37 10.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3291) COX4_pro PF03626.9 KEY68669.1 - 0.015 15.3 3.6 0.015 15.3 2.5 1.7 2 0 0 2 2 2 0 Prokaryotic Cytochrome C oxidase subunit IV Fumble PF03630.9 KEY68670.1 - 3.9e-130 433.6 0.2 3.7e-129 430.4 0.2 1.9 1 1 0 1 1 1 1 Fumble 2OG-FeII_Oxy_3 PF13640.1 KEY68674.1 - 8.2e-07 29.4 0.0 1.3e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KEY68674.1 - 0.0001 21.8 0.3 0.00018 21.0 0.2 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RdRP PF05183.7 KEY68675.1 - 2.1e-171 571.5 0.0 2.9e-171 571.1 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.17 KEY68675.1 - 0.0089 15.6 0.0 0.041 13.5 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY68675.1 - 0.01 15.7 0.1 2.9 7.9 0.0 3.6 4 0 0 4 4 4 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FAD-oxidase_C PF02913.14 KEY68676.1 - 3.1e-59 200.2 0.2 5.7e-59 199.4 0.0 1.5 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KEY68676.1 - 4.7e-33 113.5 0.0 1.1e-32 112.4 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 KEY68676.1 - 0.078 11.4 0.0 0.13 10.7 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) YfdX PF10938.3 KEY68676.1 - 0.29 10.7 1.2 0.99 9.0 0.3 2.0 2 0 0 2 2 2 0 YfdX protein Ribosomal_S4e PF00900.15 KEY68677.1 - 4.3e-31 106.4 0.3 8.7e-31 105.4 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 KEY68677.1 - 5.4e-18 64.5 1.8 1e-17 63.6 1.2 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 KEY68677.1 - 2.5e-05 23.6 0.0 4.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 KEY68677.1 - 0.00012 21.6 1.4 0.00012 21.6 1.0 3.0 4 0 0 4 4 4 1 KOW motif Myb_DNA-binding PF00249.26 KEY68678.1 - 2.4e-09 37.0 0.1 2.2e-05 24.4 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEY68678.1 - 3.2e-09 36.7 0.0 0.00091 19.2 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF605 PF04652.11 KEY68680.1 - 0.0072 15.7 32.9 0.08 12.3 13.3 2.1 2 0 0 2 2 2 2 Vta1 like Myb_DNA-bind_6 PF13921.1 KEY68680.1 - 0.083 13.0 0.3 0.21 11.7 0.2 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Septin PF00735.13 KEY68681.1 - 9e-34 116.7 0.1 4.6e-12 45.5 0.0 3.3 3 0 0 3 3 3 3 Septin AAA_23 PF13476.1 KEY68681.1 - 0.00038 20.8 0.0 0.00064 20.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEY68681.1 - 0.00093 20.0 1.1 0.026 15.3 0.0 2.8 2 2 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KEY68681.1 - 0.0019 17.7 0.0 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family KAP_NTPase PF07693.9 KEY68681.1 - 0.0082 15.1 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.1 KEY68681.1 - 0.024 14.6 0.0 0.07 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.7 KEY68681.1 - 0.029 13.6 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_18 PF13238.1 KEY68681.1 - 0.035 14.4 0.1 0.37 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KEY68681.1 - 0.036 14.5 0.1 0.13 12.7 0.0 2.0 2 1 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 KEY68681.1 - 0.04 13.4 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEY68681.1 - 0.046 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KEY68681.1 - 0.055 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin G-alpha PF00503.15 KEY68681.1 - 0.078 11.6 0.0 0.16 10.6 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit ABC1 PF03109.11 KEY68682.1 - 1.8e-21 76.3 0.0 3.9e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 KEY68682.1 - 0.0004 20.2 0.0 0.0009 19.0 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family SUR7 PF06687.7 KEY68683.1 - 1.3e-26 93.4 12.0 1.3e-26 93.4 8.3 1.4 2 0 0 2 2 2 1 SUR7/PalI family UPF0542 PF15086.1 KEY68683.1 - 0.088 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 NfeD PF01957.13 KEY68683.1 - 0.23 11.5 7.0 0.048 13.7 1.5 2.0 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding CDP-OH_P_transf PF01066.16 KEY68685.1 - 1.2e-15 57.6 3.4 1.2e-15 57.6 2.3 2.8 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase bZIP_1 PF00170.16 KEY68686.1 - 4.4e-08 32.9 12.4 6.6e-08 32.3 8.6 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 KEY68686.1 - 0.00057 20.1 8.3 0.00091 19.4 5.8 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor PAP1 PF08601.5 KEY68686.1 - 0.0028 17.4 0.0 0.0028 17.4 0.0 2.4 1 1 1 2 2 2 1 Transcription factor PAP1 Herpes_UL56 PF04534.7 KEY68686.1 - 0.011 15.4 1.3 0.022 14.4 0.9 1.5 1 1 0 1 1 1 0 Herpesvirus UL56 protein bZIP_2 PF07716.10 KEY68686.1 - 0.049 13.4 13.7 0.064 13.0 8.9 1.6 1 1 1 2 2 2 0 Basic region leucine zipper Draxin PF15550.1 KEY68686.1 - 0.076 12.6 2.9 0.1 12.2 2.0 1.1 1 0 0 1 1 1 0 Draxin DUF736 PF05284.7 KEY68686.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF736) Peptidase_S21 PF00716.12 KEY68686.1 - 0.11 11.8 3.7 0.2 10.9 2.6 1.4 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) Glutaredoxin2_C PF04399.8 KEY68686.1 - 0.44 10.1 2.8 0.68 9.5 2.0 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Raptor_N PF14538.1 KEY68687.1 - 8.4e-64 214.0 0.0 1.5e-63 213.2 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 KEY68687.1 - 7.9e-10 38.2 4.5 0.35 10.8 0.0 6.6 6 0 0 6 6 6 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 KEY68687.1 - 8.2e-06 25.5 0.1 0.06 13.1 0.1 2.7 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.4 KEY68687.1 - 0.00084 19.0 0.2 0.0017 18.0 0.1 1.4 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.17 KEY68687.1 - 0.058 13.5 1.7 2.7 8.2 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat Kelch_4 PF13418.1 KEY68688.1 - 2e-32 110.7 13.1 1.1e-06 28.3 0.2 6.8 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KEY68688.1 - 8.2e-32 108.6 8.2 3.4e-08 33.2 0.0 7.0 7 0 0 7 7 7 6 Kelch motif Kelch_3 PF13415.1 KEY68688.1 - 3.1e-30 103.6 11.8 5.8e-08 32.6 0.1 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.20 KEY68688.1 - 4.9e-27 93.2 1.8 8.2e-09 34.8 0.1 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 KEY68688.1 - 2.5e-25 87.5 5.9 5e-10 39.1 0.2 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.10 KEY68688.1 - 1.9e-17 62.2 10.9 9.2e-06 25.2 0.2 6.6 6 1 0 6 6 6 5 Kelch motif RAG2 PF03089.9 KEY68688.1 - 0.09 11.4 0.2 2.1 6.9 0.0 3.1 4 0 0 4 4 4 0 Recombination activating protein 2 Neisseria_TspB PF05616.8 KEY68688.1 - 3.5 5.8 11.2 6 5.1 7.8 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein SMC_N PF02463.14 KEY68689.1 - 7.2e-27 94.0 0.0 1.3e-26 93.2 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KEY68689.1 - 2.3e-13 50.9 17.4 2.3e-13 50.9 12.1 4.9 2 2 1 3 3 2 1 AAA domain AAA_21 PF13304.1 KEY68689.1 - 6.8e-08 32.8 0.0 0.00024 21.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain APG6 PF04111.7 KEY68689.1 - 0.00068 18.7 77.0 0.011 14.8 7.9 5.3 3 1 2 5 5 5 4 Autophagy protein Apg6 Myosin_tail_1 PF01576.14 KEY68689.1 - 0.0012 16.6 10.1 0.0012 16.6 7.0 3.7 2 1 1 3 3 3 1 Myosin tail Reo_sigmaC PF04582.7 KEY68689.1 - 0.004 16.3 17.7 0.21 10.7 0.2 5.0 3 2 2 6 6 6 2 Reovirus sigma C capsid protein BLOC1_2 PF10046.4 KEY68689.1 - 0.0064 16.5 0.9 0.0064 16.5 0.6 7.3 4 3 3 7 7 7 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_29 PF13555.1 KEY68689.1 - 0.0092 15.4 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 KEY68689.1 - 0.03 14.5 0.1 0.2 11.8 0.1 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KEY68689.1 - 0.29 10.5 0.0 0.29 10.5 0.0 3.1 4 1 0 4 4 4 0 AAA domain DUF948 PF06103.6 KEY68689.1 - 0.3 10.9 30.4 0.38 10.6 0.4 7.0 7 1 0 7 7 7 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.7 KEY68689.1 - 0.51 10.1 0.0 0.51 10.1 0.0 6.0 5 1 0 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.2 KEY68689.1 - 1.2 9.0 82.0 0.091 12.6 1.4 7.1 3 2 3 6 6 6 0 Tropomyosin like AAA_13 PF13166.1 KEY68689.1 - 1.8 6.8 66.2 5.7 5.2 14.9 4.8 3 2 1 4 4 4 0 AAA domain CENP-F_leu_zip PF10473.4 KEY68689.1 - 3.1 7.6 79.5 0.12 12.2 9.7 6.5 3 2 3 7 7 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pkinase PF00069.20 KEY68690.1 - 1.2e-72 244.2 0.0 1.9e-72 243.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY68690.1 - 1.4e-37 129.1 0.0 1.2e-36 126.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY68690.1 - 7.4e-06 25.1 0.0 1.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEY68690.1 - 0.0045 16.7 0.0 0.018 14.7 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEY68690.1 - 0.014 14.9 0.8 0.076 12.5 0.1 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase Ctr PF04145.10 KEY68691.1 - 1.4e-29 102.9 4.0 1.8e-29 102.6 2.7 1.1 1 0 0 1 1 1 1 Ctr copper transporter family SRF-TF PF00319.13 KEY68692.1 - 8.4e-24 82.5 0.4 1.2e-23 82.0 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3246 PF11596.3 KEY68692.1 - 0.028 13.6 0.0 0.037 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) CDC45 PF02724.9 KEY68692.1 - 0.08 10.9 0.2 0.1 10.6 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Tetraspannin PF00335.15 KEY68693.1 - 0.0011 18.2 9.3 0.02 14.1 6.4 2.3 1 1 0 1 1 1 1 Tetraspanin family IgaA PF07095.6 KEY68693.1 - 0.39 8.4 1.5 0.66 7.6 1.0 1.3 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA DoxX PF07681.7 KEY68693.1 - 0.86 10.0 10.0 0.38 11.2 4.5 2.1 2 1 1 3 3 3 0 DoxX Mg_trans_NIPA PF05653.9 KEY68694.1 - 7.5e-15 54.6 9.6 1.2e-14 54.0 6.7 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 KEY68694.1 - 2e-05 24.5 14.8 0.0016 18.5 0.0 3.0 3 0 0 3 3 3 2 EamA-like transporter family vATP-synt_E PF01991.13 KEY68695.1 - 7.6e-63 211.3 9.1 8.5e-63 211.2 6.3 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit FliH PF02108.11 KEY68695.1 - 0.0054 16.6 0.3 0.051 13.4 0.1 2.5 1 1 0 2 2 2 1 Flagellar assembly protein FliH AAA_15 PF13175.1 KEY68695.1 - 0.035 13.1 3.3 0.044 12.8 2.3 1.2 1 0 0 1 1 1 0 AAA ATPase domain Methyltransf_7 PF03492.10 KEY68695.1 - 0.12 11.1 1.5 1.8 7.2 0.6 2.0 1 1 1 2 2 2 0 SAM dependent carboxyl methyltransferase Malate_synthase PF01274.17 KEY68697.1 - 1.6e-227 755.7 0.0 1.9e-227 755.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase E1-E2_ATPase PF00122.15 KEY68698.1 - 4.1e-14 52.1 0.0 1.1e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KEY68698.1 - 1.9e-12 47.7 0.9 3.9e-12 46.7 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEY68698.1 - 1.2e-11 44.3 0.0 5.7e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 KEY68698.1 - 1.6e-10 41.7 2.8 1.4e-08 35.3 1.9 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEY68698.1 - 0.012 15.2 0.4 0.028 13.9 0.3 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Aldedh PF00171.17 KEY68699.1 - 3.2e-118 395.0 0.2 3.9e-118 394.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DEAD PF00270.24 KEY68700.1 - 2.1e-44 150.9 0.0 3.6e-44 150.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY68700.1 - 3e-21 75.0 1.0 1.4e-20 72.8 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KEY68700.1 - 4.6e-05 22.3 0.0 6.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Ipi1_N PF12333.3 KEY68701.1 - 5.5e-22 77.6 1.4 1.8e-21 76.0 0.1 2.4 2 1 1 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation L_biotic_typeA PF04604.8 KEY68701.1 - 0.081 12.5 0.2 0.24 11.0 0.1 1.8 1 0 0 1 1 1 0 Type-A lantibiotic Robl_LC7 PF03259.12 KEY68702.1 - 7.7e-09 35.0 0.0 6.6e-06 25.5 0.0 2.1 1 1 1 2 2 2 2 Roadblock/LC7 domain UPF0139 PF03669.8 KEY68704.1 - 0.00027 20.4 0.0 0.00039 19.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) GRP PF07172.6 KEY68706.1 - 0.023 15.1 10.8 0.023 15.1 7.5 5.6 2 1 0 2 2 2 0 Glycine rich protein family S1-P1_nuclease PF02265.11 KEY68707.1 - 6.8e-69 232.2 0.1 7.7e-69 232.1 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease PQ-loop PF04193.9 KEY68708.1 - 1.1e-26 92.1 17.1 1.7e-16 59.4 1.3 4.7 5 0 0 5 5 5 3 PQ loop repeat Semialdhyde_dhC PF02774.13 KEY68709.1 - 7.9e-39 133.4 0.0 1e-38 133.0 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 KEY68709.1 - 6.4e-29 100.7 0.0 1.4e-28 99.6 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 KEY68709.1 - 0.0054 17.2 0.0 0.0099 16.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 KEY68709.1 - 0.0065 16.3 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus zf-RING_2 PF13639.1 KEY68710.1 - 7.8e-14 51.2 5.5 1.3e-13 50.5 3.8 1.4 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KEY68710.1 - 1.1e-10 41.0 0.0 2.7e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 KEY68710.1 - 3.6e-09 36.5 5.5 5.8e-09 35.8 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEY68710.1 - 4.1e-09 36.4 2.1 8e-09 35.4 1.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KEY68710.1 - 1.3e-08 34.3 3.1 2e-08 33.7 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEY68710.1 - 9.1e-08 31.6 3.1 1.4e-07 31.0 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY68710.1 - 2.8e-07 30.1 2.4 4.4e-07 29.5 1.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KEY68710.1 - 0.0012 18.6 1.1 0.0021 17.8 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KEY68710.1 - 0.021 14.7 3.2 0.051 13.4 2.3 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KEY68710.1 - 0.1 12.3 2.9 0.22 11.2 2.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 KEY68710.1 - 0.1 12.6 2.1 0.28 11.1 1.4 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 KEY68710.1 - 0.13 12.3 3.4 0.24 11.4 2.4 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 KEY68710.1 - 0.2 11.7 3.5 0.38 10.7 2.4 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 KEY68710.1 - 0.25 10.9 2.5 0.5 9.9 1.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 KEY68710.1 - 1.4 8.6 3.0 2.4 7.8 2.1 1.4 1 0 0 1 1 1 0 PHD-finger DUF1388 PF07142.7 KEY68711.1 - 0.18 11.5 1.8 0.19 11.4 0.1 1.9 2 0 0 2 2 2 0 Repeat of unknown function (DUF1388) AAA_13 PF13166.1 KEY68712.1 - 0.011 14.1 7.7 0.015 13.7 5.3 1.3 1 0 0 1 1 1 0 AAA domain BLOC1_2 PF10046.4 KEY68712.1 - 0.03 14.4 3.7 0.03 14.4 2.5 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GvpK PF05121.7 KEY68712.1 - 0.069 12.9 8.3 0.033 13.9 3.4 2.2 1 1 1 2 2 2 0 Gas vesicle protein K Spc24 PF08286.6 KEY68712.1 - 0.17 11.6 15.5 0.065 12.9 1.1 3.2 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 CENP-F_leu_zip PF10473.4 KEY68712.1 - 0.29 10.9 22.1 0.15 11.9 6.5 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bacillus_HBL PF05791.6 KEY68712.1 - 0.3 10.4 4.4 2.1 7.7 0.4 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Filament PF00038.16 KEY68712.1 - 0.96 8.8 22.0 8.4 5.7 15.3 2.1 1 1 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.6 KEY68712.1 - 0.96 8.0 16.7 1.2 7.6 3.5 2.1 1 1 0 1 1 1 0 Spc7 kinetochore protein TBPIP PF07106.8 KEY68712.1 - 1.5 8.3 14.5 2.3 7.7 0.8 2.6 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 KEY68712.1 - 1.8 8.1 27.9 0.77 9.3 6.7 2.3 1 1 1 2 2 2 0 IncA protein DUF3584 PF12128.3 KEY68712.1 - 1.9 5.6 20.2 2.8 5.1 14.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3618 PF12277.3 KEY68712.1 - 4 7.5 12.3 16 5.5 0.7 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) ADIP PF11559.3 KEY68712.1 - 7.7 6.3 17.8 4.2 7.2 4.4 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 KEY68712.1 - 7.8 5.3 24.4 7.5e+02 -1.2 16.9 2.2 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Zn_clus PF00172.13 KEY68713.1 - 6.8e-08 32.2 12.0 1.1e-07 31.6 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LANC_like PF05147.8 KEY68714.1 - 2.9e-28 98.4 0.0 5.2e-25 87.7 0.0 2.1 2 0 0 2 2 2 2 Lanthionine synthetase C-like protein EI24 PF07264.6 KEY68715.1 - 5.5e-06 25.9 6.2 1.6e-05 24.4 4.3 1.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) FtsX PF02687.16 KEY68719.1 - 0.043 13.5 0.8 0.071 12.8 0.6 1.3 1 0 0 1 1 1 0 FtsX-like permease family P12 PF12669.2 KEY68719.1 - 6.8 6.9 7.0 0.97 9.6 0.7 2.3 2 0 0 2 2 2 0 Virus attachment protein p12 family DUF718 PF05336.8 KEY68720.1 - 5.9e-36 122.4 0.3 7.2e-36 122.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF718) DUF792 PF05632.6 KEY68720.1 - 0.04 13.2 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF792) EGF_2 PF07974.8 KEY68721.1 - 1.9 8.7 10.5 3.5 7.8 7.3 1.4 1 0 0 1 1 1 0 EGF-like domain Carboxyl_trans PF01039.17 KEY68722.1 - 5.1e-143 476.9 0.0 6.6e-143 476.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 KEY68722.1 - 0.067 12.3 0.1 0.85 8.7 0.0 2.2 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) Acyl-CoA_dh_1 PF00441.19 KEY68723.1 - 1.4e-42 145.3 1.4 2.9e-42 144.3 1.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KEY68723.1 - 4e-32 111.1 0.1 9.9e-32 109.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KEY68723.1 - 1.8e-20 72.1 0.2 3.5e-20 71.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KEY68723.1 - 9e-13 48.6 0.1 1.9e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KEY68723.1 - 4.3e-05 23.0 0.3 0.00017 21.0 0.2 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal adh_short_C2 PF13561.1 KEY68724.1 - 6e-28 98.2 0.0 8.5e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEY68724.1 - 6.8e-22 78.1 0.2 9.5e-22 77.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY68724.1 - 1.2e-11 44.5 1.1 1.2e-11 44.5 0.1 1.4 2 0 0 2 2 2 1 KR domain DUF1752 PF08550.5 KEY68726.1 - 0.0026 17.2 1.0 0.0061 16.1 0.7 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) PGA2 PF07543.7 KEY68728.1 - 0.88 9.3 7.1 1.2 8.8 1.4 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 PHD PF00628.24 KEY68729.1 - 8.6e-09 34.9 1.4 8.6e-09 34.9 1.0 1.8 2 0 0 2 2 2 1 PHD-finger UIM PF02809.15 KEY68729.1 - 0.006 16.0 0.7 0.025 14.1 0.5 2.1 1 0 0 1 1 1 1 Ubiquitin interaction motif PHD_2 PF13831.1 KEY68729.1 - 0.011 15.0 2.5 0.018 14.3 1.7 1.4 1 0 0 1 1 1 0 PHD-finger DUF3153 PF11353.3 KEY68729.1 - 0.17 11.2 0.2 0.37 10.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) MMR_HSR1 PF01926.18 KEY68730.1 - 1.1e-13 51.1 0.0 2.2e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KEY68730.1 - 1.1e-05 24.6 0.2 2.1e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 KEY68730.1 - 0.0021 17.3 0.1 0.0053 16.0 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KEY68730.1 - 0.0051 16.6 0.0 1.8 8.3 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AAA_18 PF13238.1 KEY68730.1 - 0.0054 17.0 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KEY68730.1 - 0.0079 15.6 0.1 0.027 13.9 0.1 1.9 2 1 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 KEY68730.1 - 0.023 15.5 0.3 0.072 13.9 0.1 1.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KEY68730.1 - 0.037 13.7 0.1 0.074 12.7 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.11 KEY68730.1 - 0.045 12.8 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Arf PF00025.16 KEY68730.1 - 0.056 12.6 0.1 0.096 11.9 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Miro PF08477.8 KEY68730.1 - 0.056 13.9 0.1 0.15 12.5 0.1 1.8 1 0 0 1 1 1 0 Miro-like protein ArgK PF03308.11 KEY68730.1 - 0.081 11.6 0.2 0.18 10.5 0.1 1.6 1 1 0 1 1 1 0 ArgK protein Nbl1_Borealin_N PF10444.4 KEY68730.1 - 0.092 12.1 0.1 0.74 9.2 0.0 2.3 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal GTP_EFTU PF00009.22 KEY68730.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain HCO3_cotransp PF00955.16 KEY68731.1 - 5.2e-53 180.4 14.3 9e-29 100.4 0.7 2.1 1 1 1 2 2 2 2 HCO3- transporter family ADH_zinc_N PF00107.21 KEY68732.1 - 7.5e-14 51.3 0.0 1.5e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY68732.1 - 0.00018 21.2 0.0 0.00039 20.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PI3Ka PF00613.15 KEY68734.1 - 1.1e-57 194.2 0.2 1.8e-57 193.5 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KEY68734.1 - 1.5e-43 148.9 0.1 1.9e-42 145.3 0.1 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 KEY68734.1 - 2.3e-30 105.2 0.0 3.7e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4336 PF14234.1 KEY68735.1 - 7.6e-15 54.8 0.1 4.4e-10 39.2 0.0 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) Herpes_ORF11 PF04797.8 KEY68735.1 - 0.05 12.0 0.0 0.07 11.5 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus dUTPase protein Nse4_C PF08743.5 KEY68737.1 - 2.7e-33 113.8 0.0 5.4e-33 112.8 0.0 1.5 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 KEY68737.1 - 2.2e-19 69.0 1.1 4.7e-18 64.7 0.1 2.8 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE Fungal_trans PF04082.13 KEY68738.1 - 3.5e-06 26.0 0.1 6.5e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY68738.1 - 0.0026 17.6 1.5 0.0026 17.6 1.0 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP-synt_C PF00137.16 KEY68740.1 - 5.2e-27 93.5 25.9 4.9e-16 58.3 4.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CNH PF00780.17 KEY68741.1 - 6.6e-80 268.4 0.0 3.2e-79 266.2 0.0 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 KEY68741.1 - 2.3e-42 144.1 0.0 5.9e-42 142.8 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 KEY68741.1 - 1.5e-34 119.4 0.0 2.8e-34 118.5 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 KEY68741.1 - 2.9e-15 55.7 0.1 5.7e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pal1 PF08316.6 KEY68743.1 - 2.1e-44 151.3 3.7 8.7e-44 149.3 2.6 2.1 1 1 0 1 1 1 1 Pal1 cell morphology protein Sigma70_ECF PF07638.6 KEY68743.1 - 0.4 10.3 2.7 0.67 9.5 1.9 1.3 1 0 0 1 1 1 0 ECF sigma factor PRCC PF10253.4 KEY68743.1 - 2.6 8.6 7.1 0.53 10.9 2.0 2.0 2 1 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Flavoprotein PF02441.14 KEY68744.1 - 1.6e-40 137.7 0.1 2.3e-40 137.2 0.1 1.2 1 0 0 1 1 1 1 Flavoprotein DUF4646 PF15496.1 KEY68745.1 - 0.12 12.4 0.1 0.59 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4646) Glyco_hydro_4C PF11975.3 KEY68745.1 - 0.22 11.2 1.7 0.32 10.7 1.2 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain RabGAP-TBC PF00566.13 KEY68746.1 - 5.2e-46 156.8 0.0 1e-45 155.8 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 KEY68746.1 - 0.00033 20.3 0.7 0.07 13.0 0.2 3.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 KEY68746.1 - 0.00036 20.6 0.1 0.0039 17.2 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KEY68746.1 - 0.018 14.2 0.2 1.7 8.1 0.3 3.3 3 0 0 3 3 3 0 EF hand Pkinase PF00069.20 KEY68747.1 - 2.2e-64 217.1 0.0 2.6e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY68747.1 - 1.4e-31 109.5 0.0 1.7e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY68747.1 - 6.2e-07 28.6 0.0 8.7e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEY68747.1 - 0.016 14.9 3.3 0.044 13.5 0.1 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEY68747.1 - 0.037 12.8 0.0 0.056 12.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Exo_endo_phos PF03372.18 KEY68748.1 - 4.6e-18 66.0 0.8 8.1e-18 65.2 0.6 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.20 KEY68749.1 - 1.6e-38 132.3 0.0 2e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY68749.1 - 8.8e-14 51.1 0.0 1.2e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEY68749.1 - 1.8e-05 24.6 0.0 0.0015 18.3 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KEY68749.1 - 0.055 12.2 0.1 0.082 11.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Peptidase_C1_2 PF03051.10 KEY68753.1 - 7.5e-151 502.5 0.0 8.7e-151 502.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 KEY68753.1 - 1.4e-06 28.3 0.0 0.0058 16.5 0.0 2.3 2 0 0 2 2 2 2 Papain family cysteine protease DUF4250 PF14056.1 KEY68753.1 - 0.092 12.4 0.0 0.25 11.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) eIF-5a PF01287.15 KEY68754.1 - 1.8e-05 24.5 0.0 3.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RCR PF12273.3 KEY68754.1 - 3.8 8.0 15.2 1 9.8 0.3 2.3 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF3441 PF11923.3 KEY68755.1 - 3e-37 126.6 2.2 3.5e-37 126.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) FbpA PF05833.6 KEY68755.1 - 7.4e-37 126.9 8.7 7.4e-37 126.9 6.0 2.1 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 KEY68755.1 - 7.5e-23 80.2 0.0 1.7e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Nucleic_acid_bd PF13820.1 KEY68755.1 - 0.0097 15.5 0.0 0.03 13.9 0.0 1.8 1 0 0 1 1 1 1 Putative nucleic acid-binding region Annexin PF00191.15 KEY68756.1 - 1.2e-20 73.1 0.5 2.2e-05 24.2 0.0 4.5 4 0 0 4 4 4 4 Annexin Methyltransf_23 PF13489.1 KEY68757.1 - 0.06 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 KEY68757.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_23 PF13489.1 KEY68758.1 - 1.5e-21 76.7 0.0 2.4e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY68758.1 - 4.9e-11 42.9 0.0 9.9e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY68758.1 - 3.5e-10 39.6 0.0 5.8e-09 35.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY68758.1 - 3.8e-09 37.1 0.0 5.5e-08 33.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY68758.1 - 6.6e-09 36.1 0.0 1.5e-07 31.7 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY68758.1 - 7.4e-05 23.0 0.0 0.00028 21.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KEY68758.1 - 0.001 19.1 0.0 0.0018 18.2 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 KEY68758.1 - 0.0041 16.4 0.0 0.072 12.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KEY68758.1 - 0.015 15.3 0.0 0.072 13.1 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 KEY68758.1 - 0.036 13.1 0.0 0.074 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 KEY68758.1 - 0.036 13.1 0.0 0.061 12.4 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KEY68758.1 - 0.05 12.7 0.0 0.47 9.5 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 KEY68758.1 - 0.16 11.4 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.13 KEY68759.1 - 1.8e-34 119.0 0.0 2.4e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KEY68759.1 - 0.00026 20.7 0.0 0.00046 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain VGCC_alpha2 PF08473.6 KEY68759.1 - 0.0044 16.7 0.0 0.46 10.2 0.0 2.3 2 0 0 2 2 2 1 Neuronal voltage-dependent calcium channel alpha 2acd CheR PF01739.13 KEY68759.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain ketoacyl-synt PF00109.21 KEY68760.1 - 2.5e-65 220.4 0.5 2.2e-36 125.6 0.8 2.5 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEY68760.1 - 3.5e-56 190.8 0.2 5.7e-56 190.1 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KEY68760.1 - 1.3e-51 174.8 0.1 2.9e-51 173.6 0.1 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KEY68760.1 - 3.2e-40 137.7 0.1 7.7e-40 136.5 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase PS-DH PF14765.1 KEY68760.1 - 4.4e-40 137.6 0.0 1.3e-39 136.1 0.0 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KEY68760.1 - 1.1e-31 109.1 0.3 2.5e-31 108.0 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KEY68760.1 - 7.5e-06 25.5 0.1 2.2e-05 24.0 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 KEY68760.1 - 4.1e-05 23.7 0.0 0.00015 21.9 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 KEY68760.1 - 0.0053 16.6 0.2 0.047 13.5 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family gag-asp_proteas PF13975.1 KEY68760.1 - 0.0094 15.7 0.1 0.89 9.4 0.0 2.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Thiolase_N PF00108.18 KEY68760.1 - 0.025 13.5 0.1 0.048 12.6 0.1 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain ADH_N PF08240.7 KEY68760.1 - 0.051 13.3 0.2 0.17 11.6 0.0 1.9 2 0 0 2 2 1 0 Alcohol dehydrogenase GroES-like domain Spore_YhaL PF14147.1 KEY68760.1 - 0.16 11.4 0.0 5.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Sporulation protein YhaL MFS_1 PF07690.11 KEY68761.1 - 3.5e-29 101.6 50.4 3.4e-28 98.3 33.7 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Cupin_1 PF00190.17 KEY68762.1 - 8.9e-06 25.1 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 KEY68762.1 - 9.6e-06 25.0 0.1 1.7e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KEY68762.1 - 7.2e-05 22.4 0.1 9.5e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.9 KEY68762.1 - 0.037 13.9 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family AraC_binding PF02311.14 KEY68762.1 - 0.045 13.4 0.2 0.063 12.9 0.1 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain DUF829 PF05705.9 KEY68763.1 - 1.3e-52 178.8 0.0 1.5e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Polyketide_cyc2 PF10604.4 KEY68764.1 - 0.0046 17.1 0.7 0.0099 16.0 0.5 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Dabb PF07876.7 KEY68765.1 - 1.1e-11 44.9 0.0 1.5e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain HATPase_c PF02518.21 KEY68766.1 - 1.6e-23 82.5 0.0 3.2e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KEY68766.1 - 1.1e-16 60.8 0.8 3.6e-12 46.2 0.0 3.2 3 0 0 3 3 3 2 Response regulator receiver domain PAS_9 PF13426.1 KEY68766.1 - 1.3e-15 57.6 0.0 6.2e-06 26.5 0.0 3.8 3 0 0 3 3 3 3 PAS domain PAS PF00989.19 KEY68766.1 - 6.9e-11 41.9 0.1 0.0011 18.7 0.0 3.9 4 0 0 4 4 4 3 PAS fold PAS_3 PF08447.6 KEY68766.1 - 3.8e-09 36.5 0.0 8.7e-05 22.5 0.0 3.6 2 2 0 2 2 2 2 PAS fold PAS_4 PF08448.5 KEY68766.1 - 4.8e-09 36.2 0.2 0.023 14.7 0.0 5.0 4 1 0 4 4 4 2 PAS fold PAS_8 PF13188.1 KEY68766.1 - 1.5e-07 30.9 0.0 0.013 15.3 0.0 4.0 3 0 0 3 3 3 2 PAS domain HisKA PF00512.20 KEY68766.1 - 5.1e-07 29.5 5.3 6.5e-07 29.2 0.3 3.3 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_7 PF12860.2 KEY68766.1 - 0.045 13.7 3.0 5.2 7.1 0.0 4.8 5 0 0 5 5 5 0 PAS fold Mpv17_PMP22 PF04117.7 KEY68768.1 - 6.1e-15 54.5 1.0 6.1e-15 54.5 0.7 2.6 2 1 0 2 2 2 2 Mpv17 / PMP22 family YIF1 PF03878.10 KEY68769.1 - 5e-76 255.0 1.3 6e-76 254.7 0.9 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 KEY68769.1 - 0.49 9.8 13.8 0.28 10.6 8.1 1.6 1 1 1 2 2 2 0 Yip1 domain SRP-alpha_N PF04086.8 KEY68770.1 - 3.8e-71 239.7 0.0 5.2e-71 239.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 KEY68770.1 - 5.3e-53 179.3 0.2 9.3e-53 178.5 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 KEY68770.1 - 1e-07 31.9 0.2 3.4e-07 30.2 0.1 1.9 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 KEY68770.1 - 4.1e-05 22.5 0.0 8.7e-05 21.4 0.0 1.5 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 KEY68770.1 - 0.00015 21.2 0.2 0.00041 19.8 0.1 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 KEY68770.1 - 0.01 15.5 0.1 0.03 14.0 0.1 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 KEY68770.1 - 0.017 14.2 0.0 0.12 11.4 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.18 KEY68770.1 - 0.024 14.6 0.0 0.075 12.9 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.22 KEY68770.1 - 0.058 13.6 0.0 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 KEY68770.1 - 0.06 13.3 0.3 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 KEY68770.1 - 0.069 12.5 0.0 0.99 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain Mid2 PF04478.7 KEY68773.1 - 6.6e-05 22.3 0.4 6.6e-05 22.3 0.3 2.4 2 1 1 3 3 3 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 KEY68773.1 - 0.02 14.2 1.2 0.055 12.7 0.8 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PI-PLC-X PF00388.14 KEY68775.1 - 4.8e-55 184.9 0.0 9.5e-55 184.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KEY68775.1 - 1.9e-35 121.3 0.3 3.8e-35 120.4 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KEY68775.1 - 0.1 12.6 0.4 0.2 11.6 0.3 1.4 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like Cupin_2 PF07883.6 KEY68776.1 - 0.0061 16.0 0.1 0.0073 15.7 0.1 1.2 1 0 0 1 1 1 1 Cupin domain APH PF01636.18 KEY68777.1 - 3.4e-18 66.2 0.0 1.7e-17 63.9 0.0 2.1 2 2 0 2 2 2 1 Phosphotransferase enzyme family Acetyltransf_1 PF00583.19 KEY68779.1 - 7.1e-07 29.1 0.0 1.8e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KEY68779.1 - 8.4e-06 25.6 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KEY68779.1 - 1.8e-05 24.8 0.0 3.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEY68779.1 - 7.2e-05 22.8 0.0 0.00016 21.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEY68779.1 - 0.00077 19.1 0.0 0.0019 17.9 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KEY68779.1 - 0.0011 18.8 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DLH PF01738.13 KEY68780.1 - 1.9e-15 56.7 0.1 2.3e-15 56.4 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KEY68780.1 - 6.7e-05 22.6 0.0 8.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY68780.1 - 0.0023 17.8 0.0 0.0028 17.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEY68780.1 - 0.028 13.6 0.2 0.079 12.1 0.1 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family ACPS PF01648.15 KEY68781.1 - 6.9e-09 35.5 0.0 1.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Peptidase_A22B PF04258.8 KEY68783.1 - 6.9e-51 173.4 6.3 6.1e-50 170.3 4.3 2.1 1 1 0 1 1 1 1 Signal peptide peptidase UPF0233 PF06781.7 KEY68783.1 - 0.039 13.5 0.8 1 9.0 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) Pro_isomerase PF00160.16 KEY68784.1 - 9.4e-51 172.0 0.0 1.2e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sgf11 PF08209.6 KEY68785.1 - 1.7 8.0 7.9 0.18 11.1 2.2 1.8 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 KEY68785.1 - 7.8 6.2 8.5 0.31 10.7 0.8 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Acetyltransf_1 PF00583.19 KEY68786.1 - 2.3e-05 24.3 0.0 3.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEY68786.1 - 0.00051 20.1 0.0 0.00082 19.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4585 PF15232.1 KEY68786.1 - 0.05 13.4 0.5 0.17 11.7 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) Acetyltransf_3 PF13302.1 KEY68786.1 - 0.063 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Hexokinase_1 PF00349.16 KEY68787.1 - 2.8e-64 216.2 0.0 4.6e-64 215.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 KEY68787.1 - 1.9e-63 213.9 0.0 3.3e-63 213.1 0.0 1.4 1 0 0 1 1 1 1 Hexokinase YhdB PF14148.1 KEY68787.1 - 0.2 11.4 0.1 0.46 10.2 0.0 1.5 1 0 0 1 1 1 0 YhdB-like protein HSP70 PF00012.15 KEY68788.1 - 4.8e-11 41.3 0.2 2e-09 35.9 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 KEY68788.1 - 0.004 16.7 0.1 0.0092 15.6 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 KEY68788.1 - 0.03 12.9 0.1 0.16 10.5 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein Thaumatin PF00314.12 KEY68789.1 - 3.6e-71 238.9 4.2 4.5e-71 238.6 2.9 1.1 1 0 0 1 1 1 1 Thaumatin family Ank_2 PF12796.2 KEY68790.1 - 7.8e-11 42.1 0.1 2.9e-10 40.3 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEY68790.1 - 1.7e-10 41.0 0.1 8.1e-06 26.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KEY68790.1 - 4.9e-10 38.6 0.1 0.0017 18.0 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KEY68790.1 - 5.1e-09 35.5 0.1 0.055 13.7 0.0 3.7 3 1 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KEY68790.1 - 3.2e-06 27.2 0.1 1.1 9.5 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) TFIIS_C PF01096.13 KEY68791.1 - 2.7e-19 68.5 1.9 2.7e-19 68.5 1.3 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KEY68791.1 - 1.3e-06 27.9 0.2 1.3e-06 27.9 0.1 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Desulfoferrod_N PF06397.7 KEY68791.1 - 0.001 18.4 1.9 0.34 10.3 0.0 2.4 2 0 0 2 2 2 2 Desulfoferrodoxin, N-terminal domain Zn_Tnp_IS1595 PF12760.2 KEY68791.1 - 0.016 14.9 6.0 0.17 11.6 0.2 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-BED PF02892.10 KEY68791.1 - 0.041 13.6 2.6 6.2 6.6 0.0 3.4 3 1 1 4 4 4 0 BED zinc finger zinc_ribbon_4 PF13717.1 KEY68791.1 - 0.08 12.6 9.1 5.6 6.7 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain C1_1 PF00130.17 KEY68791.1 - 0.11 12.2 1.9 0.62 9.8 0.1 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_5 PF13719.1 KEY68791.1 - 0.12 11.9 8.9 7.6 6.2 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain Elf1 PF05129.8 KEY68791.1 - 0.16 11.7 3.7 4.5 7.0 0.1 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like DZR PF12773.2 KEY68791.1 - 0.32 10.8 5.8 0.81 9.5 0.1 2.4 2 1 0 2 2 2 0 Double zinc ribbon IBR PF01485.16 KEY68791.1 - 0.36 10.7 7.1 3.1 7.7 0.2 2.8 2 1 0 2 2 2 0 IBR domain Zn_ribbon_recom PF13408.1 KEY68791.1 - 0.36 11.1 3.4 1.1 9.5 0.1 2.5 3 1 0 3 3 3 0 Recombinase zinc beta ribbon domain zf-Mss51 PF13824.1 KEY68791.1 - 2.6 7.9 5.9 3.2 7.6 0.5 2.4 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Med31 PF05669.7 KEY68792.1 - 2e-37 127.0 0.7 2.2e-37 126.9 0.5 1.0 1 0 0 1 1 1 1 SOH1 Metallophos_2 PF12850.2 KEY68793.1 - 4.5e-12 46.0 0.0 8.5e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KEY68793.1 - 1.2e-05 24.7 2.4 0.0019 17.6 1.7 2.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Aldolase_II PF00596.16 KEY68793.1 - 0.015 14.8 0.2 0.027 14.0 0.1 1.5 1 1 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain CFEM PF05730.6 KEY68794.1 - 1.8e-10 40.5 8.2 3.9e-10 39.4 5.7 1.6 1 0 0 1 1 1 1 CFEM domain DUF1641 PF07849.6 KEY68794.1 - 0.13 11.9 0.1 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) PAP1 PF08601.5 KEY68794.1 - 3 7.4 13.2 3.7 7.1 9.1 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 GPI2 PF06432.6 KEY68795.1 - 9.3e-118 392.6 1.5 1.2e-117 392.3 1.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4231 PF14015.1 KEY68795.1 - 0.45 10.5 0.0 0.45 10.5 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) Abhydrolase_6 PF12697.2 KEY68796.1 - 6.2e-29 101.5 2.6 8.1e-29 101.1 1.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY68796.1 - 3.7e-18 65.9 0.0 5.3e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY68796.1 - 5.1e-13 48.9 0.3 2.9e-12 46.5 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KEY68796.1 - 3e-07 29.9 0.5 0.00047 19.5 0.0 2.5 3 0 0 3 3 3 2 Dienelactone hydrolase family Peptidase_S9 PF00326.16 KEY68796.1 - 0.00036 19.8 0.2 0.023 13.9 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.8 KEY68796.1 - 0.00051 19.5 0.3 0.0057 16.1 0.2 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.13 KEY68796.1 - 0.002 17.5 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF2048 PF09752.4 KEY68796.1 - 0.0023 16.8 0.1 0.0028 16.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) PhoPQ_related PF10142.4 KEY68796.1 - 0.0041 15.6 0.0 0.0063 15.0 0.0 1.3 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Esterase PF00756.15 KEY68796.1 - 0.011 15.2 0.4 0.019 14.3 0.3 1.7 1 1 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 KEY68796.1 - 0.017 14.5 0.0 4.6 6.6 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase BAAT_C PF08840.6 KEY68796.1 - 0.048 13.3 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.5 KEY68796.1 - 0.059 13.2 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_3 PF07859.8 KEY68796.1 - 0.1 12.1 0.6 0.48 9.9 0.4 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold 2-Hacid_dh_C PF02826.14 KEY68798.1 - 6e-43 146.0 0.0 2.7e-28 98.3 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KEY68798.1 - 0.0042 17.1 0.0 0.011 15.7 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding WD40 PF00400.27 KEY68799.1 - 1.9e-12 46.5 15.1 2.6e-05 23.9 0.5 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat RWD PF05773.17 KEY68799.1 - 0.0064 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 KEY68799.1 - 0.04 13.7 6.6 0.097 12.5 4.6 1.6 1 0 0 1 1 1 0 Ring finger domain UQ_con PF00179.21 KEY68800.1 - 1.9e-47 160.2 0.0 2.2e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEY68800.1 - 7.8e-05 22.4 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KEY68800.1 - 0.0043 16.7 0.1 0.0078 15.8 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 KEY68800.1 - 0.033 14.0 0.1 0.039 13.8 0.1 1.5 1 1 0 1 1 1 0 RWD domain Mt_ATP-synt_D PF05873.7 KEY68801.1 - 3.9e-15 55.8 0.8 4.8e-15 55.5 0.6 1.2 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) T2SM_b PF10741.4 KEY68801.1 - 0.011 15.3 0.4 0.57 9.8 0.0 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b Mog1 PF04603.7 KEY68801.1 - 0.095 12.6 1.3 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 Ran-interacting Mog1 protein NAC PF01849.13 KEY68802.1 - 6e-26 89.7 0.2 5.3e-25 86.7 0.1 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 KEY68802.1 - 0.0043 16.8 1.1 0.0083 15.9 0.1 2.0 2 0 0 2 2 2 1 UBA/TS-N domain PBP1_TM PF14812.1 KEY68802.1 - 2.1 8.6 7.1 1.4 9.2 1.7 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BTV_NS2 PF04514.7 KEY68802.1 - 7 5.4 8.2 1.4 7.7 2.0 1.9 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 EBV-NA3 PF05009.7 KEY68802.1 - 9.2 5.4 15.5 0.18 11.0 1.9 2.4 1 1 2 3 3 3 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Ribosomal_L14e PF01929.12 KEY68803.1 - 3e-24 85.1 2.8 4.1e-24 84.7 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 KEY68803.1 - 0.00066 19.3 0.2 0.0028 17.3 0.0 2.0 2 0 0 2 2 2 1 KOW motif DUF1687 PF07955.6 KEY68805.1 - 1.1e-17 64.3 0.2 1.2e-16 60.8 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) L51_S25_CI-B8 PF05047.11 KEY68807.1 - 3.5e-14 52.2 0.0 4.3e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MPC PF03650.8 KEY68808.1 - 8.2e-44 148.3 0.8 1.1e-43 148.0 0.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) MtN3_slv PF03083.11 KEY68808.1 - 0.082 12.7 0.4 0.15 11.9 0.3 1.5 1 1 0 1 1 1 0 Sugar efflux transporter for intercellular exchange CNH PF00780.17 KEY68809.1 - 8.1e-65 218.9 0.0 1.2e-64 218.3 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 KEY68809.1 - 1.8e-32 112.6 0.2 3.1e-32 111.8 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 KEY68809.1 - 1.5e-13 50.8 0.9 1.6e-12 47.4 0.0 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 KEY68809.1 - 4.2e-05 23.6 0.0 0.00023 21.3 0.0 2.3 2 0 0 2 2 2 1 PH domain Sod_Cu PF00080.15 KEY68810.1 - 1.1e-44 152.0 4.8 1.3e-44 151.7 3.3 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Lyase_1 PF00206.15 KEY68811.1 - 1.1e-110 369.7 0.0 1.5e-110 369.2 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 KEY68811.1 - 1.3e-22 79.6 0.0 2.7e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus SNase PF00565.12 KEY68812.1 - 8e-70 231.9 1.6 6.9e-19 68.1 0.0 5.8 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.19 KEY68812.1 - 1.1e-21 76.8 0.0 2.2e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 KEY68812.1 - 1.3e-05 24.4 0.0 3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Transaldolase PF00923.14 KEY68813.1 - 2.3e-95 319.0 0.2 2.7e-95 318.8 0.1 1.0 1 0 0 1 1 1 1 Transaldolase C5-epim_C PF06662.8 KEY68813.1 - 0.017 14.4 0.0 0.051 12.8 0.0 1.7 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Metallophos PF00149.23 KEY68814.1 - 8.6e-12 44.8 0.4 3.6e-11 42.8 0.3 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEY68814.1 - 6.7e-09 35.7 0.0 1.2e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pet191_N PF10203.4 KEY68815.1 - 1.2e-27 95.7 5.4 1.5e-27 95.4 3.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 PAN_3 PF08277.7 KEY68815.1 - 0.065 12.8 0.7 0.12 12.0 0.5 1.4 1 0 0 1 1 1 0 PAN-like domain DUF4232 PF14016.1 KEY68815.1 - 0.12 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) Cmc1 PF08583.5 KEY68815.1 - 0.25 11.1 4.8 4.7 7.0 1.2 2.5 1 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Abhydro_lipase PF04083.11 KEY68816.1 - 1e-22 79.2 0.1 2.2e-22 78.1 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KEY68816.1 - 8.1e-19 68.0 0.4 1.4e-18 67.2 0.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEY68816.1 - 2.4e-07 30.8 0.0 4.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KEY68816.1 - 1.7e-05 24.3 0.0 0.016 14.6 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KEY68816.1 - 2.2e-05 24.2 0.0 0.00011 21.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family RTA1 PF04479.8 KEY68817.1 - 2e-34 119.0 3.4 3.6e-34 118.2 2.4 1.3 1 0 0 1 1 1 1 RTA1 like protein PIRT PF15099.1 KEY68817.1 - 1.8 7.8 6.7 0.073 12.2 0.7 1.7 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family zf-CCCH PF00642.19 KEY68818.1 - 0.0017 17.9 0.1 0.0033 17.0 0.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Myosin_head PF00063.16 KEY68819.1 - 1.1e-249 830.2 0.0 1.1e-249 830.2 0.0 2.7 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KEY68819.1 - 4.6e-31 107.3 143.5 9.6e-23 79.8 54.6 7.0 2 2 4 7 7 7 5 Myosin tail Myosin_N PF02736.14 KEY68819.1 - 0.00018 21.1 0.1 0.00049 19.7 0.1 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 KEY68819.1 - 0.058 13.1 0.0 0.19 11.5 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KEY68819.1 - 0.12 12.5 0.0 0.12 12.5 0.0 4.3 4 0 0 4 4 4 0 AAA domain Reo_sigmaC PF04582.7 KEY68819.1 - 9.9 5.2 81.7 0.1 11.7 5.6 9.5 4 4 4 9 9 9 0 Reovirus sigma C capsid protein Chorismate_synt PF01264.16 KEY68820.1 - 1.5e-128 428.1 0.0 1.9e-128 427.7 0.0 1.1 1 0 0 1 1 1 1 Chorismate synthase Hormone_4 PF00220.12 KEY68820.1 - 3.7 7.4 12.7 2.4 8.0 2.3 2.6 2 0 0 2 2 2 0 Neurohypophysial hormones, N-terminal Domain DDE_1 PF03184.14 KEY68826.1 - 6.3e-12 45.1 0.0 1e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KEY68826.1 - 0.0011 18.6 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease CHAT PF12770.2 KEY68827.1 - 6.2e-12 45.2 0.4 8.6e-12 44.7 0.3 1.2 1 0 0 1 1 1 1 CHAT domain ZZ PF00569.12 KEY68828.1 - 9.1e-10 37.9 5.7 1.7e-09 37.0 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Epimerase PF01370.16 KEY68831.1 - 3e-12 46.4 0.1 6.1e-12 45.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY68831.1 - 1.3e-08 35.0 1.0 1.3e-07 31.7 0.7 2.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KEY68831.1 - 9.9e-08 32.0 2.4 9.9e-08 32.0 1.7 1.8 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KEY68831.1 - 2.4e-06 26.4 0.0 3.6e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KEY68831.1 - 1.4e-05 24.1 1.1 0.0025 16.7 0.0 2.3 2 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 KEY68831.1 - 4.6e-05 22.4 0.1 6.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KEY68831.1 - 0.0002 21.0 0.9 0.00045 19.9 0.6 1.5 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 KEY68831.1 - 0.00087 19.6 0.2 0.004 17.5 0.1 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 KEY68831.1 - 0.0049 16.1 0.2 0.0083 15.4 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_2 PF03446.10 KEY68831.1 - 0.073 12.9 0.0 0.17 11.7 0.0 1.7 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase An_peroxidase PF03098.10 KEY68832.1 - 2.1e-13 49.5 0.0 2.4e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase DUF2235 PF09994.4 KEY68832.1 - 0.13 11.6 0.0 1.3 8.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) LysM PF01476.15 KEY68834.1 - 4.3e-17 61.7 0.0 7e-06 25.8 0.0 4.3 4 0 0 4 4 4 3 LysM domain Glyco_hydro_18 PF00704.23 KEY68835.1 - 1.7e-52 178.9 4.7 7.4e-51 173.6 3.3 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KEY68835.1 - 0.003 17.5 13.7 0.003 17.5 9.5 4.7 4 0 0 4 4 4 2 Chitin recognition protein LysM PF01476.15 KEY68837.1 - 2.5e-13 49.6 0.0 0.024 14.5 0.0 4.4 4 0 0 4 4 4 4 LysM domain NLPC_P60 PF00877.14 KEY68837.1 - 0.00052 19.7 0.0 1.6 8.5 0.0 3.1 3 0 0 3 3 3 2 NlpC/P60 family Herpes_TK_C PF08465.5 KEY68837.1 - 0.0038 16.7 0.4 1.5 8.4 0.0 3.4 3 0 0 3 3 3 1 Thymidine kinase from Herpesvirus C-terminal HTH_23 PF13384.1 KEY68837.1 - 0.026 14.1 0.0 13 5.6 0.0 3.1 4 0 0 4 4 4 0 Homeodomain-like domain LRV_FeS PF05484.6 KEY68837.1 - 0.034 13.7 0.0 3.9 7.1 0.0 3.2 3 0 0 3 3 3 0 LRV protein FeS4 cluster HTH_28 PF13518.1 KEY68837.1 - 0.075 13.0 0.0 9.7 6.3 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain CarbpepA_inh PF02977.10 KEY68837.1 - 1.1 8.9 8.7 5.5 6.6 0.1 4.3 4 0 0 4 4 4 0 Carboxypeptidase A inhibitor Fmp27_SW PF10305.4 KEY68840.1 - 0.048 14.1 0.0 0.061 13.7 0.0 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CYTH PF01928.16 KEY68840.1 - 0.12 12.0 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 CYTH domain Tsp45I PF06300.7 KEY68841.1 - 0.025 14.0 0.0 0.027 13.9 0.0 1.1 1 0 0 1 1 1 0 Tsp45I type II restriction enzyme PAF-AH_p_II PF03403.8 KEY68842.1 - 1.4e-11 43.3 0.0 1.3e-05 23.6 0.0 2.2 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KEY68842.1 - 7.8e-11 41.9 0.3 1.3e-10 41.2 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY68842.1 - 1.1e-07 31.9 1.7 1.2e-07 31.8 0.5 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY68842.1 - 0.0066 16.0 0.1 0.0087 15.6 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.6 KEY68842.1 - 0.05 12.3 0.0 0.074 11.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase GMC_oxred_N PF00732.14 KEY68843.1 - 6.2e-26 91.2 0.2 2.6e-11 43.2 0.0 3.3 1 1 1 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.1 KEY68843.1 - 0.05 13.6 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEY68843.1 - 0.095 11.5 0.0 7.3 5.3 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KEY68845.1 - 1.8e-14 53.5 0.6 1.6e-06 27.4 0.1 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KEY68845.1 - 1.9e-05 24.5 0.1 6.5e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KEY68845.1 - 0.0039 17.0 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEY68845.1 - 0.023 13.5 0.3 0.083 11.7 0.2 1.8 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEY68845.1 - 0.032 14.6 0.0 1.2 9.6 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase BCS1_N PF08740.6 KEY68846.1 - 8.6e-24 84.1 0.2 1.6e-23 83.2 0.1 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KEY68846.1 - 2.7e-18 66.4 0.0 6.5e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KEY68846.1 - 0.00047 19.2 0.0 0.00093 18.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KEY68846.1 - 0.0027 17.4 0.1 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 KEY68846.1 - 0.0034 16.8 0.0 0.0072 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEY68846.1 - 0.0038 16.9 0.0 0.048 13.3 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KEY68846.1 - 0.0041 17.9 0.8 0.012 16.4 0.2 2.3 2 1 0 2 2 1 1 AAA domain AAA_11 PF13086.1 KEY68846.1 - 0.018 14.6 0.4 0.053 13.0 0.3 1.9 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 KEY68846.1 - 0.03 13.4 0.3 0.068 12.2 0.0 1.7 2 0 0 2 2 2 0 KaiC RNA_helicase PF00910.17 KEY68846.1 - 0.044 13.9 0.0 0.58 10.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.1 KEY68846.1 - 0.047 13.8 0.0 0.28 11.3 0.0 2.4 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.12 KEY68846.1 - 0.07 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 KEY68846.1 - 0.089 11.4 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_16 PF13191.1 KEY68846.1 - 0.17 11.8 0.1 0.17 11.8 0.1 2.7 3 1 0 3 3 3 0 AAA ATPase domain AAA_24 PF13479.1 KEY68846.1 - 0.18 11.3 0.9 1.2 8.6 0.2 2.2 2 0 0 2 2 2 0 AAA domain UbiA PF01040.13 KEY68847.1 - 3.6e-22 78.8 21.0 4.7e-22 78.4 14.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family IDO PF01231.13 KEY68848.1 - 4.6e-140 466.7 0.0 5.5e-140 466.5 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 KEY68848.1 - 0.046 12.2 0.0 0.11 10.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) Aminotran_5 PF00266.14 KEY68849.1 - 4.3e-10 38.8 0.0 6.6e-09 34.9 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KEY68849.1 - 0.062 12.3 0.0 0.12 11.3 0.0 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family p450 PF00067.17 KEY68850.1 - 6.2e-46 156.8 0.0 1.7e-45 155.4 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 Metallophos PF00149.23 KEY68851.1 - 3.8e-14 52.5 0.3 4.3e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEY68851.1 - 2.1e-06 27.6 0.0 1.7e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RTA1 PF04479.8 KEY68852.1 - 1.6e-29 102.9 7.8 2.6e-29 102.3 5.4 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF751 PF05421.6 KEY68852.1 - 1.8 8.8 11.7 0.38 11.0 0.3 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF751) Zn_clus PF00172.13 KEY68853.1 - 2.5e-08 33.6 7.4 5.5e-08 32.5 5.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NMO PF03060.10 KEY68854.1 - 5.5e-36 124.3 8.9 1.6e-27 96.5 2.2 2.3 2 1 0 2 2 2 2 Nitronate monooxygenase Glu_synthase PF01645.12 KEY68854.1 - 7.9e-08 31.5 0.1 1.2e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KEY68854.1 - 9.8e-06 24.6 0.3 7.1e-05 21.8 0.2 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KEY68854.1 - 0.00014 20.8 0.7 0.00022 20.1 0.5 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Sugar_tr PF00083.19 KEY68855.1 - 1.8e-106 356.4 18.8 2.1e-106 356.2 13.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY68855.1 - 7.2e-20 70.9 36.2 3.1e-15 55.7 10.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 KEY68856.1 - 2.3e-25 89.4 0.1 3e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY68856.1 - 1.1e-09 38.4 0.0 1.6e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY68856.1 - 2.1e-07 30.8 0.0 2.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY68856.1 - 4.1e-05 23.1 0.0 7.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY68856.1 - 0.00011 22.2 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 KEY68856.1 - 0.00031 19.9 0.0 0.00048 19.3 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_2 PF03446.10 KEY68857.1 - 2.3e-13 50.3 0.0 3.6e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KEY68857.1 - 2.1e-07 31.2 0.2 5.1e-07 30.0 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KEY68857.1 - 3.2e-06 26.9 0.6 5.8e-05 22.8 0.4 2.1 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 KEY68857.1 - 0.00062 18.9 0.0 0.0012 17.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KEY68857.1 - 0.0011 19.1 0.1 0.0016 18.5 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KEY68857.1 - 0.0027 17.3 0.3 0.0073 15.9 0.0 1.7 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KEY68857.1 - 0.0032 16.9 0.1 0.0085 15.5 0.1 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.11 KEY68859.1 - 1.2e-35 122.8 43.3 1.7e-26 92.7 28.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.14 KEY68859.1 - 0.00087 17.9 0.0 0.00087 17.9 0.0 2.3 2 1 0 2 2 2 1 LacY proton/sugar symporter Ceramidase PF05875.7 KEY68860.1 - 3.2e-56 190.3 7.1 3.8e-56 190.1 5.0 1.0 1 0 0 1 1 1 1 Ceramidase VCBS PF13517.1 KEY68861.1 - 0.026 14.8 0.7 4.9 7.5 0.0 2.1 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF3012 PF11216.3 KEY68861.1 - 0.35 10.5 2.2 16 5.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3012) VCBS PF13517.1 KEY68862.1 - 1.2e-07 31.9 0.1 0.0004 20.6 0.0 2.1 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella HET PF06985.6 KEY68862.1 - 0.0015 18.6 6.7 0.19 11.8 4.6 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FG-GAP PF01839.18 KEY68862.1 - 0.0057 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 FG-GAP repeat HET PF06985.6 KEY68863.1 - 1.6e-09 38.0 0.0 1.8e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Zn_clus PF00172.13 KEY68864.1 - 4.3e-07 29.7 13.7 7.3e-07 28.9 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEY68864.1 - 0.0025 16.4 0.0 0.004 15.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPP_enzyme_N PF02776.13 KEY68865.1 - 4.8e-39 133.5 0.2 6.8e-38 129.8 0.0 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KEY68865.1 - 5.5e-23 81.2 0.1 7.8e-22 77.4 0.0 2.7 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KEY68865.1 - 3.6e-22 78.6 0.1 1.1e-21 77.0 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.11 KEY68865.1 - 0.018 14.5 0.1 0.033 13.7 0.1 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Ldh_1_N PF00056.18 KEY68866.1 - 4.4e-28 97.8 0.3 6.2e-28 97.3 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KEY68866.1 - 1.3e-12 47.8 0.0 2.1e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ThiF PF00899.16 KEY68866.1 - 0.0011 18.7 2.6 0.008 15.9 1.7 2.6 2 1 0 2 2 2 1 ThiF family UDPG_MGDP_dh_N PF03721.9 KEY68866.1 - 0.0014 18.0 0.9 0.0054 16.1 0.3 2.2 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_4 PF02056.11 KEY68866.1 - 0.0019 17.5 0.1 0.0089 15.3 0.0 1.9 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase Malic_M PF03949.10 KEY68866.1 - 0.031 13.8 0.0 0.046 13.2 0.0 1.5 1 1 0 1 1 1 0 Malic enzyme, NAD binding domain ApbA PF02558.11 KEY68866.1 - 0.064 12.6 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Methyltransf_26 PF13659.1 KEY68866.1 - 0.08 12.9 0.1 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain PPDK_N PF01326.14 KEY68867.1 - 5.1e-94 314.9 0.0 1.2e-93 313.7 0.0 1.6 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.13 KEY68867.1 - 5.5e-61 206.0 0.0 8.2e-61 205.4 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.18 KEY68867.1 - 1.1e-22 79.4 0.7 5.5e-22 77.1 0.4 2.2 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain Serine_rich PF08824.5 KEY68869.1 - 0.0015 18.2 0.2 0.031 13.9 0.1 2.2 2 0 0 2 2 2 1 Serine rich protein interaction domain bZIP_2 PF07716.10 KEY68869.1 - 0.056 13.2 5.0 0.13 12.1 3.4 1.6 1 0 0 1 1 1 0 Basic region leucine zipper MFS_1 PF07690.11 KEY68870.1 - 5.9e-15 54.8 11.0 7.2e-15 54.5 7.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY68870.1 - 0.00098 17.8 0.1 0.001 17.7 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Tautomerase_3 PF14832.1 KEY68871.1 - 4.2e-48 162.8 0.6 4.7e-48 162.6 0.4 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Epimerase PF01370.16 KEY68872.1 - 3.1e-15 56.2 0.0 5e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY68872.1 - 1.7e-10 41.2 0.3 2.5e-09 37.3 0.2 2.1 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEY68872.1 - 5.2e-08 31.9 0.0 8.8e-08 31.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KEY68872.1 - 1.1e-06 27.8 0.0 3.1e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KEY68872.1 - 0.00019 20.7 0.0 0.0003 20.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KEY68872.1 - 0.0004 20.3 0.0 0.0022 17.9 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KEY68872.1 - 0.0005 19.0 0.0 0.0011 17.9 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 KEY68872.1 - 0.0049 16.6 0.0 0.0082 15.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain KR PF08659.5 KEY68872.1 - 0.12 12.0 0.2 7 6.2 0.1 2.5 2 1 0 2 2 2 0 KR domain Fungal_trans PF04082.13 KEY68873.1 - 1.4e-09 37.2 0.0 2.3e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY68873.1 - 2.5e-08 33.6 6.7 2.5e-08 33.6 4.6 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2318 PF10080.4 KEY68873.1 - 0.88 9.3 3.4 9.4 6.0 0.5 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Methyltransf_2 PF00891.13 KEY68876.1 - 1.5e-27 96.3 0.0 2e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase HTH_27 PF13463.1 KEY68876.1 - 0.006 16.8 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.17 KEY68876.1 - 0.0067 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.2 KEY68876.1 - 0.0072 15.9 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.15 KEY68876.1 - 0.016 15.3 0.0 0.074 13.1 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator HTH_5 PF01022.15 KEY68876.1 - 0.059 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family FeoC PF09012.5 KEY68876.1 - 0.16 11.6 0.0 0.42 10.3 0.0 1.6 2 0 0 2 2 2 0 FeoC like transcriptional regulator DUF732 PF05305.9 KEY68877.1 - 0.011 15.7 0.1 0.019 15.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF732) Transket_pyr PF02779.19 KEY68878.1 - 1.6e-32 112.4 0.1 2.2e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KEY68878.1 - 7.8e-07 29.0 0.0 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain eIF-1a PF01176.14 KEY68878.1 - 0.1 12.0 0.1 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Aldo_ket_red PF00248.16 KEY68879.1 - 3.6e-46 157.2 0.0 4.3e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldedh PF00171.17 KEY68880.1 - 5.6e-67 226.0 0.1 3.4e-42 144.3 0.2 3.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Peptidase_S8 PF00082.17 KEY68882.1 - 2.2e-37 128.7 8.4 2.2e-37 128.7 5.8 1.5 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 KEY68882.1 - 1e-08 35.6 0.0 1.8e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Acetyltransf_1 PF00583.19 KEY68883.1 - 1.6e-16 60.0 0.1 2.3e-16 59.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KEY68883.1 - 2.6e-09 37.1 0.0 3.1e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KEY68883.1 - 1.9e-08 34.4 0.0 2e-08 34.3 0.0 1.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KEY68883.1 - 3.5e-07 30.2 0.0 4.8e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEY68883.1 - 1.7e-06 27.7 0.0 2.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KEY68883.1 - 2.9e-06 27.3 0.0 3.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KEY68883.1 - 1.8e-05 24.8 0.0 2.1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KEY68883.1 - 0.0047 16.7 0.0 0.0089 15.8 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase ATE_C PF04377.10 KEY68883.1 - 0.027 14.5 0.0 0.089 12.8 0.0 1.7 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, C terminus ADH_zinc_N PF00107.21 KEY68884.1 - 7e-27 93.5 0.5 1.3e-26 92.6 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY68884.1 - 1.6e-15 58.1 0.1 3.5e-15 57.0 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY68884.1 - 5.6e-10 38.9 0.0 9.1e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KEY68884.1 - 0.0077 15.8 0.2 0.013 15.0 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 KEY68884.1 - 0.054 13.5 1.3 0.093 12.7 0.9 1.5 1 1 0 1 1 1 0 NADH(P)-binding EamA PF00892.15 KEY68885.1 - 0.062 13.3 0.1 0.062 13.3 0.1 2.0 2 1 0 2 2 2 0 EamA-like transporter family AAA PF00004.24 KEY68887.1 - 1.9e-20 73.3 0.0 3.6e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEY68887.1 - 0.00049 19.8 0.1 0.0029 17.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEY68887.1 - 0.0013 18.9 0.1 0.015 15.4 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KEY68887.1 - 0.005 16.8 0.0 0.018 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 KEY68887.1 - 0.0084 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ETC_C1_NDUFA5 PF04716.9 KEY68887.1 - 0.028 13.9 0.0 0.062 12.8 0.0 1.6 1 0 0 1 1 1 0 ETC complex I subunit conserved region AAA_24 PF13479.1 KEY68887.1 - 0.032 13.8 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KEY68887.1 - 0.058 12.4 0.0 0.098 11.6 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus GFA PF04828.9 KEY68888.1 - 4e-21 74.7 1.7 5.5e-21 74.3 1.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-B_box PF00643.19 KEY68888.1 - 3.5 7.6 7.1 6.3 6.7 0.0 3.2 3 0 0 3 3 3 0 B-box zinc finger OppC_N PF12911.2 KEY68889.1 - 0.053 12.8 0.0 2.4 7.5 0.0 2.4 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Glyco_hydro_31 PF01055.21 KEY68890.1 - 9.2e-131 436.6 0.9 1.1e-130 436.4 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KEY68890.1 - 0.00024 20.8 0.9 0.003 17.3 0.1 3.1 3 1 0 3 3 3 1 Galactose mutarotase-like Sugar_tr PF00083.19 KEY68891.1 - 2e-75 254.1 27.9 2.4e-75 253.8 19.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY68891.1 - 1.3e-13 50.3 33.8 1.8e-13 49.9 20.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 KEY68894.1 - 2.2e-30 105.7 0.1 3.7e-30 105.0 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY68894.1 - 3.1e-13 49.7 0.5 1.7e-12 47.3 0.4 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY68894.1 - 2.9e-09 37.0 0.0 6e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEY68894.1 - 7.9e-07 28.7 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY68894.1 - 8.4e-07 29.1 0.0 1.5e-06 28.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEY68894.1 - 4.2e-06 25.6 0.1 6e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1776 PF08643.5 KEY68894.1 - 0.0055 15.8 0.1 0.0077 15.3 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_4 PF07993.7 KEY68894.1 - 0.012 14.5 0.0 0.022 13.6 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein 2-Hacid_dh_C PF02826.14 KEY68894.1 - 0.017 14.2 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF348 PF03990.9 KEY68894.1 - 0.042 13.4 0.1 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF348) RmlD_sub_bind PF04321.12 KEY68894.1 - 0.05 12.4 0.0 0.079 11.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Saccharop_dh PF03435.13 KEY68894.1 - 0.056 12.4 0.0 0.097 11.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Peptidase_M20 PF01546.23 KEY68895.1 - 5.5e-12 45.5 0.6 1.7e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 ABC2_membrane PF01061.19 KEY68896.1 - 1.6e-94 314.9 47.2 6.4e-48 162.6 11.6 2.4 2 0 0 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.7 KEY68896.1 - 9.4e-37 124.8 0.6 6.5e-30 102.8 0.0 3.0 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 KEY68896.1 - 9.4e-34 116.6 0.0 3.5e-16 59.7 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 KEY68896.1 - 1.2e-18 66.9 0.0 3.7e-18 65.3 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KEY68896.1 - 3.2e-08 33.2 0.0 0.00012 21.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEY68896.1 - 6.6e-07 29.4 0.6 0.00012 22.1 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KEY68896.1 - 6.8e-06 26.0 0.0 0.015 15.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 KEY68896.1 - 4.6e-05 22.9 0.4 0.0058 16.0 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KEY68896.1 - 0.00011 21.8 0.0 0.14 11.9 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain DUF258 PF03193.11 KEY68896.1 - 0.0002 20.5 0.0 0.0032 16.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KEY68896.1 - 0.00053 20.7 0.0 0.64 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KEY68896.1 - 0.00071 19.2 0.3 1 9.0 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_29 PF13555.1 KEY68896.1 - 0.00085 18.8 0.9 0.025 14.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KEY68896.1 - 0.0011 19.1 0.4 0.81 9.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KEY68896.1 - 0.0011 18.6 0.2 1.3 8.6 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 KEY68896.1 - 0.0011 19.2 0.1 0.22 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KEY68896.1 - 0.0012 19.0 0.1 0.22 11.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 KEY68896.1 - 0.016 15.2 0.0 0.77 9.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.1 KEY68896.1 - 0.036 13.6 0.1 3.3 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KEY68896.1 - 0.046 14.0 0.0 0.48 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KEY68896.1 - 0.083 12.8 0.2 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KEY68896.1 - 0.1 12.3 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_14 PF13173.1 KEY68896.1 - 0.11 12.3 0.0 18 5.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KEY68896.1 - 0.12 11.7 0.2 15 4.8 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain Viral_helicase1 PF01443.13 KEY68896.1 - 0.14 11.6 0.1 3.1 7.2 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 KEY68896.1 - 0.16 10.8 0.2 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.12 KEY68896.1 - 0.2 11.0 0.1 13 5.1 0.0 2.6 3 0 0 3 3 2 0 IstB-like ATP binding protein Miro PF08477.8 KEY68896.1 - 0.21 12.0 0.0 13 6.2 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein DUF2273 PF10031.4 KEY68896.1 - 0.87 9.2 7.9 0.44 10.1 0.4 3.0 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) ABC2_membrane_3 PF12698.2 KEY68896.1 - 4.6 6.1 48.6 0.19 10.7 12.8 3.2 2 2 0 2 2 2 0 ABC-2 family transporter protein Zn_clus PF00172.13 KEY68898.1 - 1.2e-08 34.7 9.5 2.1e-08 33.9 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KEY68898.1 - 0.14 12.3 7.1 0.26 11.4 4.9 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region AA_permease_2 PF13520.1 KEY68899.1 - 1.3e-47 162.3 54.5 1.6e-47 162.0 37.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEY68899.1 - 5.2e-24 84.4 41.4 7.2e-24 83.9 28.7 1.1 1 0 0 1 1 1 1 Amino acid permease Epiglycanin_C PF14654.1 KEY68899.1 - 0.2 11.6 3.0 3.7 7.5 0.2 2.5 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Fungal_trans PF04082.13 KEY68900.1 - 6.1e-31 107.2 0.0 8.9e-31 106.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 KEY68900.1 - 9e-09 35.4 0.2 2.5e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KEY68900.1 - 0.00016 21.1 0.0 0.00026 20.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY68900.1 - 0.00019 21.4 0.2 0.00073 19.5 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KEY68900.1 - 0.0004 19.7 0.2 0.00074 18.8 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 KEY68900.1 - 0.00045 19.1 0.4 0.00075 18.4 0.2 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Rax2 PF12768.2 KEY68901.1 - 0.0059 15.8 0.0 0.0081 15.4 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Mito_fiss_reg PF05308.6 KEY68901.1 - 0.0065 15.8 2.3 0.0065 15.8 1.6 1.8 2 0 0 2 2 2 1 Mitochondrial fission regulator SKG6 PF08693.5 KEY68901.1 - 0.0071 15.6 1.5 0.0071 15.6 1.0 2.3 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Alpha_GJ PF03229.8 KEY68901.1 - 0.009 16.3 5.4 0.013 15.8 3.2 1.6 1 1 0 1 1 1 1 Alphavirus glycoprotein J Yip1 PF04893.12 KEY68901.1 - 0.038 13.4 0.1 0.079 12.4 0.0 1.5 2 0 0 2 2 2 0 Yip1 domain TMEM154 PF15102.1 KEY68901.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family VSP PF03302.8 KEY68901.1 - 0.082 11.5 0.3 0.15 10.7 0.2 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF1517 PF07466.6 KEY68901.1 - 0.11 11.4 0.2 0.16 10.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Herpes_gE PF02480.11 KEY68901.1 - 0.11 10.7 0.1 0.15 10.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Hemerythrin PF01814.18 KEY68902.1 - 4.9e-15 55.8 1.6 7.1e-15 55.3 1.1 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain WSC PF01822.14 KEY68903.1 - 1e-49 166.3 50.3 7.8e-20 70.6 7.9 6.0 6 0 0 6 6 6 3 WSC domain PAN_1 PF00024.21 KEY68903.1 - 1.8e-12 46.8 26.9 7.6e-05 22.3 0.0 7.9 8 0 0 8 8 8 4 PAN domain PAN_4 PF14295.1 KEY68903.1 - 2.7e-06 26.9 62.5 0.0084 15.7 0.7 9.5 10 0 0 10 10 10 6 PAN domain Glyco_hydro_61 PF03443.9 KEY68906.1 - 0.0016 18.3 0.0 0.26 11.0 0.0 3.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Fungal_trans PF04082.13 KEY68907.1 - 1.6e-10 40.3 0.0 2.8e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY68907.1 - 1.7e-07 31.0 12.7 3.4e-07 30.0 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.6 KEY68908.1 - 1.3e-20 73.9 8.0 4.9e-18 65.6 1.2 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Cellulase PF00150.13 KEY68909.1 - 4.9e-40 137.4 0.0 6.8e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Mucin PF01456.12 KEY68909.1 - 0.05 13.3 10.8 0.094 12.4 7.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Oxysterol_BP PF01237.13 KEY68910.1 - 5.1e-62 209.4 0.0 7.2e-62 208.9 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein DUF2914 PF11141.3 KEY68910.1 - 0.07 12.6 0.4 0.51 9.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2914) adh_short PF00106.20 KEY68911.1 - 3.6e-24 85.5 0.8 6.8e-24 84.6 0.5 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY68911.1 - 1.2e-18 67.7 0.1 2.2e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY68911.1 - 2e-09 37.3 0.4 3.7e-09 36.5 0.3 1.4 1 0 0 1 1 1 1 KR domain Hydrolase_like PF13242.1 KEY68911.1 - 2.1e-08 33.7 0.1 4.6e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 KEY68911.1 - 3.1e-07 30.7 0.0 4e-05 23.9 0.0 2.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NAD_binding_10 PF13460.1 KEY68911.1 - 0.00051 20.0 0.4 0.031 14.2 0.3 2.7 2 0 0 2 2 2 1 NADH(P)-binding Hydrolase PF00702.21 KEY68911.1 - 0.0036 17.7 0.0 0.025 15.0 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Eno-Rase_NADH_b PF12242.3 KEY68911.1 - 0.16 11.8 0.7 0.48 10.2 0.5 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ank_2 PF12796.2 KEY68912.1 - 1.4e-75 249.6 2.4 3.8e-23 81.6 0.1 7.2 4 2 4 8 8 8 6 Ankyrin repeats (3 copies) Ank PF00023.25 KEY68912.1 - 7.8e-60 195.8 16.4 1.7e-09 36.9 0.0 12.6 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.1 KEY68912.1 - 1.6e-47 159.0 3.5 1.2e-12 47.9 0.1 8.5 4 2 4 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY68912.1 - 5.6e-42 137.5 4.5 1.8e-05 24.5 0.0 12.9 13 0 0 13 13 13 9 Ankyrin repeat Ank_5 PF13857.1 KEY68912.1 - 8.9e-42 140.1 11.7 1.5e-09 37.7 0.1 10.4 3 1 9 12 12 12 11 Ankyrin repeats (many copies) NACHT PF05729.7 KEY68912.1 - 6.1e-06 25.9 0.0 1.7e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KEY68912.1 - 0.0055 16.8 0.1 0.026 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain adh_short PF00106.20 KEY68913.1 - 7.9e-26 90.9 0.3 1.4e-23 83.6 0.2 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY68913.1 - 1.3e-20 74.1 0.0 5.3e-19 68.9 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY68913.1 - 1.7e-11 44.1 0.1 1.6e-09 37.6 0.0 2.2 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 KEY68913.1 - 0.00034 20.1 0.1 0.00065 19.2 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KEY68913.1 - 0.0025 16.9 0.0 0.0037 16.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KEY68913.1 - 0.0072 16.3 0.0 0.021 14.8 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 KEY68913.1 - 0.037 14.1 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KEY68913.1 - 0.083 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Protoglobin PF11563.3 KEY68915.1 - 7.9e-55 184.8 0.1 9.7e-55 184.5 0.0 1.1 1 0 0 1 1 1 1 Protoglobin DUF2538 PF10804.3 KEY68915.1 - 0.12 12.2 0.2 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2538) SNF PF00209.13 KEY68917.1 - 4e-79 266.4 37.6 4.5e-78 262.9 26.1 2.0 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Sugar_tr PF00083.19 KEY68918.1 - 5.1e-94 315.3 25.1 6.4e-94 315.0 17.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY68918.1 - 7.1e-20 71.0 19.7 7.1e-20 71.0 13.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.18 KEY68919.1 - 3.8e-18 65.2 1.7 9.8e-18 63.9 0.7 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KEY68919.1 - 2.6e-08 33.6 0.0 1.1e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like ADH_zinc_N PF00107.21 KEY68920.1 - 4.8e-19 68.1 0.1 1.3e-18 66.7 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY68920.1 - 0.0005 20.9 0.0 0.0015 19.4 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 KEY68921.1 - 5.5e-19 68.6 1.1 7.5e-19 68.2 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY68921.1 - 2.5e-11 43.8 0.0 3.1e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEY68921.1 - 0.00014 21.3 0.1 0.00021 20.8 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1537 PF07005.6 KEY68921.1 - 0.09 12.4 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF1537 ketoacyl-synt PF00109.21 KEY68922.1 - 3.8e-70 236.2 0.1 1e-69 234.8 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEY68922.1 - 7e-56 189.8 0.9 1.1e-55 189.2 0.6 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KEY68922.1 - 6e-50 170.0 0.1 9.8e-50 169.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KEY68922.1 - 6.8e-40 135.6 0.1 2e-39 134.1 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KEY68922.1 - 9.9e-18 63.9 0.0 2.8e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KR PF08659.5 KEY68922.1 - 1.2e-17 64.1 0.3 4.8e-17 62.2 0.1 2.2 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KEY68922.1 - 6.6e-15 55.4 0.3 6.6e-15 55.4 0.2 2.4 3 0 0 3 3 3 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 KEY68922.1 - 1.4e-10 42.0 0.0 7e-10 39.8 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY68922.1 - 1.7e-07 30.9 0.0 4.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain HhH-GPD PF00730.20 KEY68923.1 - 1.4e-15 57.5 0.0 2.9e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Anp1 PF03452.9 KEY68924.1 - 2.4e-108 361.3 0.0 2.9e-108 361.1 0.0 1.1 1 0 0 1 1 1 1 Anp1 Snf7 PF03357.16 KEY68925.1 - 9.1e-26 90.2 19.1 9.1e-26 90.2 13.2 2.2 1 1 1 2 2 2 1 Snf7 Allexi_40kDa PF05549.6 KEY68925.1 - 0.36 10.0 6.4 0.15 11.3 2.0 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF3138 PF11336.3 KEY68925.1 - 2 6.4 8.1 1.9 6.5 3.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) CFEM PF05730.6 KEY68926.1 - 0.016 14.9 4.3 0.034 13.9 3.0 1.5 1 0 0 1 1 1 0 CFEM domain SKG6 PF08693.5 KEY68926.1 - 0.065 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1469 PF07332.6 KEY68927.1 - 3.7 7.3 12.1 0.023 14.4 1.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Pkinase PF00069.20 KEY68929.1 - 3.8e-55 186.8 0.0 5.4e-55 186.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY68929.1 - 6.2e-19 68.0 0.0 1.1e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEY68929.1 - 0.024 14.3 0.0 0.068 12.9 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEY68929.1 - 0.071 12.6 0.6 0.14 11.7 0.4 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 KEY68929.1 - 0.33 10.2 0.1 0.62 9.3 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Pex24p PF06398.6 KEY68930.1 - 7.8e-96 320.9 0.9 9e-96 320.7 0.6 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.7 KEY68930.1 - 0.075 11.1 0.2 0.11 10.5 0.2 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) DUF3292 PF11696.3 KEY68930.1 - 0.18 9.6 1.6 0.22 9.3 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3292) polyprenyl_synt PF00348.12 KEY68931.1 - 2.7e-56 190.3 0.0 3.2e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CDC14 PF08045.6 KEY68932.1 - 4.1e-90 301.3 0.0 5e-44 150.3 0.0 2.0 1 1 1 2 2 2 2 Cell division control protein 14, SIN component SKG6 PF08693.5 KEY68933.1 - 0.063 12.6 1.1 0.12 11.7 0.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Podoplanin PF05808.6 KEY68933.1 - 0.097 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 Podoplanin DUF1049 PF06305.6 KEY68933.1 - 0.36 10.3 0.1 0.36 10.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) IDO PF01231.13 KEY68934.1 - 5.2e-40 137.1 0.0 7.2e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase INO80_Ies4 PF08193.6 KEY68936.1 - 1.9e-65 220.9 20.4 2.4e-65 220.6 14.2 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 CLTH PF10607.4 KEY68937.1 - 1.1e-34 119.2 0.1 1.8e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 KEY68937.1 - 2.9e-24 85.5 0.1 4.6e-24 84.8 0.1 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 KEY68937.1 - 2.3e-05 23.9 0.4 0.00021 20.9 0.0 2.6 3 0 0 3 3 3 1 LisH GST_C_3 PF14497.1 KEY68938.1 - 0.0016 18.9 0.1 0.0025 18.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 KEY68938.1 - 0.05 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 KEY68938.1 - 0.07 13.0 0.7 0.17 11.7 0.5 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain adh_short PF00106.20 KEY68940.1 - 1.6e-26 93.1 4.2 2.1e-26 92.8 2.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY68940.1 - 3.1e-17 63.1 0.0 3.8e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY68940.1 - 3.8e-10 39.7 1.4 5.1e-10 39.3 0.9 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KEY68940.1 - 0.079 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TPMT PF05724.6 KEY68941.1 - 3.1e-26 92.1 0.0 1.7e-24 86.5 0.0 2.0 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.1 KEY68941.1 - 1e-06 28.5 0.0 1.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY68941.1 - 1.7e-05 24.4 0.0 7.1e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY68941.1 - 2.2e-05 24.9 0.0 3.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY68941.1 - 0.00012 22.5 0.0 0.00035 20.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 KEY68941.1 - 0.00036 19.7 0.0 0.00055 19.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.7 KEY68941.1 - 0.00049 20.5 0.0 0.0014 19.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY68941.1 - 0.0012 18.8 0.1 0.0023 17.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain OTU PF02338.14 KEY68942.1 - 4.8e-18 65.8 0.9 1.4e-17 64.3 0.0 2.1 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KEY68942.1 - 0.00084 18.7 0.1 0.96 8.7 0.0 2.5 3 0 0 3 3 3 2 Peptidase C65 Otubain TATR PF03430.8 KEY68942.1 - 7.1 5.1 10.0 8.5 4.8 7.0 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Mcp5_PH PF12814.2 KEY68943.1 - 3.5e-47 159.3 0.0 8.4e-47 158.1 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.7 KEY68943.1 - 2.3 7.9 22.7 0.069 12.8 8.2 2.4 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Ras PF00071.17 KEY68945.1 - 1.1e-50 171.1 0.0 2.2e-50 170.1 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KEY68945.1 - 2.6e-16 60.2 0.0 1.5e-14 54.4 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KEY68945.1 - 0.0017 17.6 0.0 0.0048 16.1 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KEY68945.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.13 KEY68945.1 - 0.047 12.9 0.1 0.47 9.7 0.0 2.2 2 1 1 3 3 3 0 Ferrous iron transport protein B AAA_25 PF13481.1 KEY68945.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Abhydrolase_6 PF12697.2 KEY68945.1 - 0.15 11.8 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Syndecan PF01034.15 KEY68946.1 - 0.028 14.0 0.1 0.05 13.2 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain P12 PF12669.2 KEY68946.1 - 0.23 11.6 0.1 0.23 11.6 0.1 2.4 2 0 0 2 2 2 0 Virus attachment protein p12 family Opy2 PF09463.5 KEY68946.1 - 0.9 9.6 19.6 1.4 9.0 13.6 1.3 1 0 0 1 1 1 0 Opy2 protein Chitin_synth_1 PF01644.12 KEY68947.1 - 5.8e-70 234.3 0.0 8.5e-70 233.7 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 KEY68947.1 - 3.2e-28 98.4 0.1 7.9e-23 80.6 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 KEY68947.1 - 8.7e-27 92.6 0.1 1.6e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 KEY68947.1 - 1.6e-11 44.3 1.2 6.6e-11 42.2 0.8 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KEY68947.1 - 3.4e-09 36.8 0.0 1.3e-08 34.9 0.0 2.0 3 0 0 3 3 3 1 Glycosyltransferase like family 2 UQ_con PF00179.21 KEY68948.1 - 1.1e-35 122.1 0.0 1.5e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEY68948.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B IlvC PF01450.14 KEY68949.1 - 1.9e-46 157.5 0.0 2.9e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.7 KEY68949.1 - 3.5e-45 153.3 0.0 5.2e-45 152.7 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 KEY68949.1 - 0.02 15.3 0.2 0.056 13.8 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KEY68949.1 - 0.081 12.7 0.0 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase PALP PF00291.20 KEY68950.1 - 5.5e-61 206.4 1.4 7.3e-61 206.0 0.9 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KEY68950.1 - 0.016 14.2 0.4 0.025 13.6 0.2 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family MFS_1 PF07690.11 KEY68951.1 - 1.7e-44 151.9 44.8 3e-40 138.0 18.9 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY68951.1 - 9e-09 34.4 6.5 9e-09 34.4 4.5 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.8 KEY68951.1 - 0.6 8.1 18.5 1.1 7.3 5.4 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Aldedh PF00171.17 KEY68952.1 - 9.7e-18 63.7 13.0 1.1e-10 40.4 6.6 2.7 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Tbf5 PF06331.7 KEY68952.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Rep_fac-A_C PF08646.5 KEY68953.1 - 7.4e-50 168.4 0.8 4.9e-47 159.3 0.3 2.5 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 KEY68953.1 - 2.5e-17 62.5 0.1 8.9e-17 60.7 0.1 1.9 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 KEY68953.1 - 5.9e-15 54.8 0.3 4.6e-11 42.4 0.0 3.6 3 1 1 4 4 4 2 OB-fold nucleic acid binding domain POT1 PF02765.12 KEY68953.1 - 0.043 13.7 0.0 0.098 12.5 0.0 1.6 1 0 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 zinc-ribbons_6 PF07191.7 KEY68953.1 - 0.12 12.2 1.0 0.35 10.6 0.7 1.8 1 0 0 1 1 1 0 zinc-ribbons DLH PF01738.13 KEY68954.1 - 1.8e-17 63.3 0.0 5.3e-08 32.4 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KEY68954.1 - 1.6e-08 34.3 0.1 2.4e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY68954.1 - 0.0005 20.0 0.3 0.62 9.9 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY68954.1 - 0.01 15.3 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KEY68954.1 - 0.076 12.5 0.0 0.17 11.4 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold ADH_zinc_N PF00107.21 KEY68955.1 - 1.4e-22 79.6 0.1 2.4e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY68955.1 - 2.3e-20 73.7 0.0 5.7e-20 72.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY68955.1 - 2.6e-11 43.2 0.0 6.1e-10 38.8 0.0 2.2 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain Flocculin_t3 PF13928.1 KEY68956.1 - 0.002 18.2 6.0 0.002 18.2 4.2 3.5 1 1 2 3 3 3 1 Flocculin type 3 repeat DUF3724 PF12521.3 KEY68956.1 - 0.92 9.3 4.4 22 5.0 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3724) AMP-binding PF00501.23 KEY68957.1 - 4.3e-76 255.9 0.0 5.1e-76 255.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEY68957.1 - 4.7e-16 59.4 0.2 2e-15 57.5 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain BRCT PF00533.21 KEY68958.1 - 1.6e-05 24.9 0.0 4.7e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KEY68958.1 - 2.3e-05 24.1 0.1 0.00032 20.5 0.0 2.2 2 0 0 2 2 2 1 twin BRCT domain KilA-N PF04383.8 KEY68959.1 - 0.00033 20.2 0.0 0.0046 16.5 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain Kinetocho_Slk19 PF12709.2 KEY68960.1 - 2.9e-22 78.5 0.4 2.9e-22 78.5 0.3 4.7 3 1 2 5 5 5 2 Central kinetochore-associated FlaC_arch PF05377.6 KEY68960.1 - 0.0096 15.7 15.8 0.026 14.3 0.5 4.5 4 0 0 4 4 4 2 Flagella accessory protein C (FlaC) DUF2605 PF10792.4 KEY68960.1 - 0.1 12.2 3.4 0.2 11.3 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2605) Reo_sigmaC PF04582.7 KEY68960.1 - 0.17 11.0 1.6 8.3 5.4 0.1 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 KEY68960.1 - 0.21 11.3 40.7 0.18 11.6 1.6 4.7 2 2 3 5 5 5 0 TATA element modulatory factor 1 DNA binding CENP-K PF11802.3 KEY68960.1 - 0.84 8.8 16.0 0.053 12.7 1.7 2.9 2 2 0 2 2 2 0 Centromere-associated protein K Filament PF00038.16 KEY68960.1 - 2.6 7.4 32.9 13 5.1 22.9 2.3 1 1 0 1 1 1 0 Intermediate filament protein ATG16 PF08614.6 KEY68960.1 - 2.9 7.6 34.1 0.39 10.5 7.5 4.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF2570 PF10828.3 KEY68960.1 - 7 6.2 13.8 1.8 8.1 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Tropomyosin_1 PF12718.2 KEY68960.1 - 9.7 6.0 39.7 0.2 11.5 13.9 3.4 2 1 0 3 3 3 0 Tropomyosin like Amidohydro_2 PF04909.9 KEY68961.1 - 9.1e-24 84.4 0.6 1.2e-23 84.0 0.4 1.3 1 0 0 1 1 1 1 Amidohydrolase CBM_20 PF00686.14 KEY68962.1 - 0.029 13.9 0.2 0.067 12.7 0.1 1.6 1 0 0 1 1 1 0 Starch binding domain DUF4614 PF15391.1 KEY68962.1 - 0.24 11.1 21.2 0.1 12.3 8.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Senescence_reg PF04520.8 KEY68962.1 - 0.29 11.6 10.3 0.56 10.6 5.0 2.2 2 0 0 2 2 2 0 Senescence regulator DDHD PF02862.12 KEY68962.1 - 0.39 10.4 9.9 8.9 6.0 4.5 2.2 2 0 0 2 2 2 0 DDHD domain Transformer PF06495.6 KEY68962.1 - 0.42 10.4 14.3 0.77 9.6 9.9 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein Pex14_N PF04695.8 KEY68962.1 - 0.5 10.4 10.8 8.6 6.4 4.2 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RAP1 PF07218.6 KEY68962.1 - 0.73 7.8 24.6 0.0049 15.0 7.4 2.2 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Zip PF02535.17 KEY68962.1 - 1.8 7.4 6.0 2.5 7.0 4.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF572 PF04502.8 KEY68962.1 - 2.3 7.3 8.8 3.1 6.9 6.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Apt1 PF10351.4 KEY68962.1 - 7.9 5.2 15.8 0.51 9.1 6.1 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain Sdh5 PF03937.11 KEY68963.1 - 6.3e-25 86.6 0.2 1.2e-24 85.7 0.1 1.5 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase HD PF01966.17 KEY68964.1 - 3.5e-06 27.0 0.3 7.9e-06 25.8 0.1 1.7 2 0 0 2 2 2 1 HD domain 3A PF00803.13 KEY68964.1 - 0.05 12.6 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 3A/RNA2 movement protein family DUF706 PF05153.10 KEY68964.1 - 0.073 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF706) Macoilin PF09726.4 KEY68965.1 - 0.24 9.6 2.7 0.32 9.2 1.9 1.1 1 0 0 1 1 1 0 Transmembrane protein zf-U1 PF06220.7 KEY68968.1 - 6.7e-22 76.7 3.4 1.1e-21 76.1 2.4 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 KEY68968.1 - 0.012 15.7 4.7 0.026 14.6 3.2 1.6 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding EMP24_GP25L PF01105.19 KEY68969.1 - 3.4e-40 137.6 0.0 4.3e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Helicase_RecD PF05127.9 KEY68969.1 - 0.022 14.3 0.0 0.068 12.8 0.0 1.8 1 1 1 2 2 2 0 Helicase DASH_Dad2 PF08654.5 KEY68969.1 - 0.094 12.7 0.2 0.14 12.1 0.2 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad2 Nup54 PF13874.1 KEY68969.1 - 0.12 12.0 0.3 0.18 11.4 0.2 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 MIS13 PF08202.6 KEY68970.1 - 3.9e-57 193.6 0.8 6.6e-57 192.8 0.6 1.3 1 0 0 1 1 1 1 Mis12-Mtw1 protein family DUF4140 PF13600.1 KEY68970.1 - 1.2 9.6 5.6 1.6 9.1 0.2 3.0 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Aft1_HRA PF11786.3 KEY68971.1 - 2.8e-29 101.1 9.5 2.8e-29 101.1 6.6 3.8 4 1 0 4 4 4 1 Aft1 HRA domain Aft1_HRR PF11787.3 KEY68971.1 - 3.4e-24 85.6 5.2 3.4e-24 85.6 3.6 3.1 4 0 0 4 4 4 1 Aft1 HRR domain Aft1_OSA PF11785.3 KEY68971.1 - 1.6e-19 70.1 8.2 1.6e-19 70.1 5.7 3.6 4 0 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.16 KEY68971.1 - 2.6e-13 49.7 6.5 3.9e-13 49.1 4.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KEY68971.1 - 1.8e-06 27.6 7.1 2.7e-06 27.0 4.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KEY68971.1 - 0.0021 18.3 3.1 0.004 17.4 2.2 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor DivIC PF04977.10 KEY68971.1 - 0.35 10.3 1.3 0.59 9.6 0.9 1.3 1 0 0 1 1 1 0 Septum formation initiator GST_N_3 PF13417.1 KEY68972.1 - 9.7e-10 38.5 0.2 2.1e-09 37.4 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KEY68972.1 - 3.4e-06 26.9 0.0 5.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEY68972.1 - 1.9e-05 25.0 0.0 3.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KEY68972.1 - 0.00025 20.8 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KEY68972.1 - 0.022 14.7 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain zf-CCHC PF00098.18 KEY68974.1 - 5.3e-53 174.5 84.4 4.2e-07 29.5 2.3 10.2 10 0 0 10 10 10 10 Zinc knuckle zf-CCHC_4 PF14392.1 KEY68974.1 - 4.9e-07 29.3 67.6 0.27 10.9 0.4 10.2 10 0 0 10 10 10 8 Zinc knuckle zf-CCHC_2 PF13696.1 KEY68974.1 - 2.7e-06 26.7 54.7 0.0067 15.8 0.3 8.8 4 4 5 9 9 9 5 Zinc knuckle zf-CCHC_3 PF13917.1 KEY68974.1 - 8.6e-06 25.3 70.5 0.042 13.5 1.1 9.9 2 2 8 10 10 10 6 Zinc knuckle zf-CCHC_6 PF15288.1 KEY68974.1 - 0.11 12.2 74.1 0.4 10.3 0.3 10.0 7 2 3 10 10 10 0 Zinc knuckle Peptidase_S10 PF00450.17 KEY68975.1 - 6.9e-113 377.9 0.0 9.2e-113 377.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Act-Frag_cataly PF09192.5 KEY68975.1 - 0.012 14.5 0.1 0.019 13.9 0.1 1.2 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic Abhydrolase_6 PF12697.2 KEY68975.1 - 0.021 14.7 0.0 0.084 12.7 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family RNA_Me_trans PF04252.8 KEY68976.1 - 7.5e-45 152.7 0.0 8.6e-45 152.5 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Acetyltransf_1 PF00583.19 KEY68978.1 - 2.1e-08 34.0 0.1 4e-08 33.1 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEY68978.1 - 2.2e-07 30.9 0.0 1.1e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEY68978.1 - 9.8e-07 28.9 1.1 3.4e-05 23.9 0.6 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEY68978.1 - 0.0005 19.9 0.1 0.0013 18.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEY68978.1 - 0.0068 16.1 0.0 0.018 14.7 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.1 KEY68978.1 - 0.007 16.2 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DDA1 PF10172.4 KEY68978.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Det1 complexing ubiquitin ligase Fungal_trans PF04082.13 KEY68979.1 - 1.7e-10 40.2 0.0 2.6e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SPX PF03105.14 KEY68981.1 - 9.1e-18 65.0 6.0 2.5e-12 47.1 1.1 2.9 2 1 1 3 3 3 2 SPX domain Exonuc_VII_L PF02601.10 KEY68981.1 - 0.03 13.5 0.3 0.044 12.9 0.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2939 PF11159.3 KEY68981.1 - 0.053 13.7 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Bcl-2 PF00452.14 KEY68981.1 - 0.13 12.3 0.1 0.41 10.7 0.1 1.8 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family DEAD PF00270.24 KEY68982.1 - 3.8e-46 156.6 0.0 1.3e-43 148.4 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY68982.1 - 2.5e-22 78.5 0.1 5.8e-11 42.1 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KEY68982.1 - 0.00015 21.6 0.0 0.00039 20.2 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2443 PF10398.4 KEY68982.1 - 0.021 14.5 0.6 0.05 13.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Helicase_C_2 PF13307.1 KEY68982.1 - 0.041 13.8 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain POTRA_2 PF08479.6 KEY68982.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 POTRA domain, ShlB-type Pyr_redox_2 PF07992.9 KEY68983.1 - 4.6e-26 91.9 0.0 8.1e-25 87.8 0.0 3.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY68983.1 - 1.5e-14 54.1 0.0 1.4e-12 47.8 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY68983.1 - 0.0035 17.4 0.3 0.44 10.5 0.1 3.1 2 1 2 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KEY68983.1 - 0.011 15.9 0.0 4.9 7.4 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Rubrerythrin PF02915.12 KEY68983.1 - 0.089 13.1 1.9 0.25 11.6 0.1 2.3 2 0 0 2 2 2 0 Rubrerythrin XhlA PF10779.4 KEY68983.1 - 5.8 6.9 6.0 12 5.9 0.4 2.6 2 0 0 2 2 2 0 Haemolysin XhlA Phos_pyr_kin PF08543.7 KEY68985.1 - 1.8e-76 256.6 0.1 2.3e-76 256.2 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 KEY68985.1 - 2e-35 122.4 0.1 6.6e-18 65.2 0.0 2.2 2 0 0 2 2 2 2 TENA/THI-4/PQQC family PfkB PF00294.19 KEY68985.1 - 2.3e-09 36.8 0.0 7.5e-09 35.1 0.0 1.6 1 1 1 2 2 2 1 pfkB family carbohydrate kinase HK PF02110.10 KEY68985.1 - 0.022 13.9 1.2 0.21 10.7 0.7 2.5 2 1 0 2 2 2 0 Hydroxyethylthiazole kinase family RICTOR_N PF14664.1 KEY68986.1 - 3.2e-137 457.0 2.6 1e-135 452.1 0.5 2.8 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 KEY68986.1 - 1.9e-89 298.5 0.7 4.4e-88 294.0 0.1 2.9 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 KEY68986.1 - 1.7e-42 143.9 0.0 9.9e-41 138.2 0.0 2.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 KEY68986.1 - 1.5e-29 101.7 0.4 1.2e-27 95.6 0.1 3.6 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 KEY68986.1 - 1.1e-12 47.5 8.6 3.4e-12 45.9 6.0 1.9 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.1 KEY68986.1 - 0.0026 17.7 6.7 0.0075 16.2 4.7 1.7 1 0 0 1 1 1 1 Up-regulated During Septation IncA PF04156.9 KEY68986.1 - 0.0034 17.0 2.0 0.0068 16.0 1.4 1.4 1 0 0 1 1 1 1 IncA protein Noelin-1 PF12308.3 KEY68986.1 - 0.22 11.3 1.3 0.74 9.6 0.9 1.9 1 0 0 1 1 1 0 Neurogenesis glycoprotein Allexi_40kDa PF05549.6 KEY68986.1 - 0.55 9.4 2.5 1.2 8.4 1.8 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein Uricase PF01014.13 KEY68987.1 - 3.1e-87 289.6 2.0 6.9e-48 162.2 0.4 2.0 2 0 0 2 2 2 2 Uricase Ribosomal_L13 PF00572.13 KEY68988.1 - 3.4e-40 137.0 0.0 4.4e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 HMA PF00403.21 KEY68989.1 - 7.6e-13 48.3 0.1 1.3e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.15 KEY68989.1 - 1.8e-10 41.1 0.0 3.4e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) TPR_11 PF13414.1 KEY68990.1 - 7e-16 57.6 3.1 6.6e-11 41.6 0.1 3.3 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 KEY68990.1 - 2.1e-15 55.5 2.7 6.5e-08 31.8 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEY68990.1 - 1.3e-13 49.6 5.6 4.6e-06 26.1 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEY68990.1 - 1.9e-10 39.7 0.5 6.2e-05 22.4 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEY68990.1 - 3e-09 36.6 1.6 5.9e-06 26.1 0.0 2.6 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEY68990.1 - 2.3e-08 33.2 0.1 1.9e-06 27.2 0.0 3.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEY68990.1 - 8.5e-08 32.1 0.1 0.044 14.2 0.0 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat PB1 PF00564.19 KEY68990.1 - 1e-06 28.2 0.3 2e-06 27.3 0.2 1.5 1 0 0 1 1 1 1 PB1 domain TPR_17 PF13431.1 KEY68990.1 - 1.5e-06 27.9 0.1 0.0095 16.0 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEY68990.1 - 0.00033 21.2 6.6 0.0014 19.2 0.8 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEY68990.1 - 0.0013 19.2 0.9 0.015 15.8 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KEY68990.1 - 0.0029 17.4 0.3 1.7 8.5 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc5 PF12862.2 KEY68990.1 - 0.054 13.3 0.1 0.2 11.4 0.0 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_4 PF07721.9 KEY68990.1 - 0.079 13.4 0.5 28 5.5 0.0 3.6 3 1 0 3 3 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KEY68990.1 - 0.11 12.6 0.3 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KEY68990.1 - 0.12 12.3 0.1 4.2 7.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat tRNA-synt_1c PF00749.16 KEY68991.1 - 2e-88 296.1 0.0 2.7e-88 295.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DnaJ PF00226.26 KEY68992.1 - 1.9e-24 85.1 4.8 3.7e-24 84.2 3.3 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KEY68992.1 - 1.2e-20 73.2 0.2 1.2e-18 66.7 0.0 3.0 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KEY68992.1 - 6.6e-14 51.7 18.8 1.1e-13 51.0 13.0 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KEY68992.1 - 0.0049 16.5 8.3 0.098 12.3 1.0 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Malate_DH PF12434.3 KEY68992.1 - 0.015 15.0 0.4 0.042 13.5 0.3 1.8 1 0 0 1 1 1 0 Malate dehydrogenase enzyme DUF1356 PF07092.7 KEY68992.1 - 0.16 11.0 3.4 1.4 8.0 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1356) zf-CHY PF05495.7 KEY68992.1 - 1.4 9.1 8.8 3.9 7.6 0.8 2.4 2 0 0 2 2 2 0 CHY zinc finger Cytochrom_c3_2 PF14537.1 KEY68992.1 - 5.6 7.3 10.4 13 6.2 7.0 1.8 1 1 0 1 1 1 0 Cytochrome c3 EAP30 PF04157.11 KEY68993.1 - 3e-61 206.4 0.0 3.6e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family HTH_42 PF06224.7 KEY68993.1 - 0.067 12.5 0.3 0.1 11.9 0.2 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain Mpv17_PMP22 PF04117.7 KEY68994.1 - 8.1e-10 38.1 1.6 1.6e-08 34.0 1.1 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF1275 PF06912.6 KEY68994.1 - 0.016 14.3 2.1 0.87 8.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) PDH PF02153.12 KEY68996.1 - 4.4e-14 52.0 0.0 6.4e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 KEY68996.1 - 1.8e-07 31.5 0.0 3.5e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KEY68996.1 - 2.3e-06 27.5 0.0 4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KEY68996.1 - 4.3e-05 22.7 0.0 7.5e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 KEY68996.1 - 0.00074 18.9 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KEY68996.1 - 0.004 16.8 0.0 0.0081 15.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 KEY68996.1 - 0.013 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain RCC1 PF00415.13 KEY68997.1 - 2.7e-27 94.7 19.5 3e-10 40.1 0.1 6.8 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEY68997.1 - 1.8e-20 72.0 33.7 4.9e-07 29.2 1.5 6.2 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat DUF1163 PF06651.6 KEY68997.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1163) Rad9 PF04139.8 KEY68998.1 - 1.6e-64 217.4 0.0 1.9e-64 217.2 0.0 1.1 1 0 0 1 1 1 1 Rad9 Glyco_hydro_18 PF00704.23 KEY69000.1 - 2.4e-68 231.1 0.0 2.9e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.3 KEY69000.1 - 4.9e-06 26.3 0.0 8.9e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) FAR1 PF03101.10 KEY69001.1 - 3.6e-05 24.2 0.2 6.4e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 KEY69001.1 - 0.0017 18.4 0.5 0.0033 17.5 0.3 1.4 1 1 0 1 1 1 1 Transcription factor AFT DUF1664 PF07889.7 KEY69001.1 - 0.02 14.7 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) XhlA PF10779.4 KEY69001.1 - 0.021 14.7 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Haemolysin XhlA DHC_N1 PF08385.7 KEY69001.1 - 0.074 11.4 0.0 0.097 11.0 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Sugarporin_N PF11471.3 KEY69001.1 - 0.2 11.3 0.9 0.37 10.4 0.6 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Ribosomal_L34e PF01199.13 KEY69003.1 - 3.4e-36 123.3 3.4 4.7e-36 122.8 2.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e DUF1428 PF07237.6 KEY69003.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) zf-ribbon_3 PF13248.1 KEY69003.1 - 0.15 11.3 1.6 0.34 10.1 0.0 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_recom PF13408.1 KEY69003.1 - 0.68 10.2 3.9 0.19 11.9 0.3 1.8 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain FhuF_C PF11575.3 KEY69003.1 - 4.1 7.1 8.0 2.5 7.8 0.2 2.6 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain DUF498 PF04430.9 KEY69004.1 - 3.1e-27 94.2 0.0 4.8e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Abhydrolase_6 PF12697.2 KEY69005.1 - 1.2e-22 80.8 3.7 2.7e-22 79.7 2.5 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY69005.1 - 3e-15 56.2 0.0 6.9e-15 55.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY69005.1 - 2.4e-10 40.3 0.0 2.4e-09 37.0 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold DSPc PF00782.15 KEY69005.1 - 2.9e-10 39.8 0.0 5.7e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.15 KEY69005.1 - 2.7e-06 27.7 0.0 8.1e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain PTPlike_phytase PF14566.1 KEY69005.1 - 1.1e-05 25.5 0.0 2.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Abhydrolase_4 PF08386.5 KEY69005.1 - 0.0007 19.4 0.2 0.0049 16.7 0.0 2.4 2 0 0 2 2 2 1 TAP-like protein Y_phosphatase PF00102.22 KEY69005.1 - 0.0013 18.1 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PGAP1 PF07819.8 KEY69005.1 - 0.0013 18.3 0.0 0.004 16.7 0.0 1.8 1 1 0 1 1 1 1 PGAP1-like protein DUF2305 PF10230.4 KEY69005.1 - 0.0087 15.5 0.0 0.028 13.8 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 KEY69005.1 - 0.036 13.9 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 Putative lysophospholipase DLH PF01738.13 KEY69005.1 - 0.11 11.8 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family LCAT PF02450.10 KEY69005.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Alk_phosphatase PF00245.15 KEY69006.1 - 8.4e-109 364.0 0.0 1e-108 363.7 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 KEY69006.1 - 4e-05 23.1 0.0 7.6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily RskA PF10099.4 KEY69006.1 - 0.06 13.0 0.2 0.2 11.3 0.0 1.9 2 0 0 2 2 2 0 Anti-sigma-K factor rskA CorA PF01544.13 KEY69009.1 - 1.2e-30 106.6 10.7 1.1e-25 90.3 5.0 2.6 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein ACR_tran PF00873.14 KEY69009.1 - 0.0089 13.5 0.0 0.013 12.9 0.0 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family DNA_ligase_A_M PF01068.16 KEY69011.1 - 2.3e-44 151.2 0.0 4.8e-44 150.1 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KEY69011.1 - 6.3e-38 130.3 0.0 2e-37 128.7 0.0 1.9 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KEY69011.1 - 1.3e-14 54.3 0.5 4.7e-14 52.5 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_IV PF11411.3 KEY69011.1 - 2.1e-05 24.1 0.0 6.8e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 DNA ligase IV BRCT PF00533.21 KEY69011.1 - 0.00013 22.0 0.0 0.0022 18.1 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.14 KEY69011.1 - 0.014 15.1 0.8 4.2 7.0 0.0 3.5 3 1 0 3 3 3 0 mRNA capping enzyme, catalytic domain UPRTase PF14681.1 KEY69012.1 - 1.2e-72 243.4 0.0 1.4e-72 243.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KEY69012.1 - 9.9e-08 31.7 0.1 1.9e-07 30.8 0.1 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain TMP-TENI PF02581.12 KEY69012.1 - 0.032 13.3 0.7 0.33 10.0 0.1 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI CRCB PF02537.10 KEY69013.1 - 3.7e-30 104.2 30.1 4.6e-20 71.6 5.8 4.1 3 1 1 4 4 4 3 CrcB-like protein Renin_r PF07850.9 KEY69013.1 - 0.075 13.3 0.1 5.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Renin receptor-like protein DUF4470 PF14737.1 KEY69014.1 - 9.6e-11 41.3 0.0 1.8e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 KEY69014.1 - 3.3e-07 30.0 11.8 6.5e-07 29.1 8.2 1.5 1 0 0 1 1 1 1 MYND finger DUF905 PF06006.7 KEY69014.1 - 0.078 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) zf-Mss51 PF13824.1 KEY69014.1 - 0.75 9.7 4.2 1.2 9.0 2.1 2.0 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Amidohydro_4 PF13147.1 KEY69015.1 - 1.1e-09 38.8 4.0 1.8e-08 34.7 1.1 3.4 2 2 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 KEY69015.1 - 1e-06 28.6 0.2 2.5e-05 24.0 0.0 2.8 3 0 0 3 3 3 1 Amidohydrolase family Amidohydro_5 PF13594.1 KEY69015.1 - 2e-06 27.5 3.0 2.2e-06 27.4 0.2 2.5 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 KEY69015.1 - 9.1e-05 21.8 0.2 0.00022 20.5 0.0 1.7 2 0 0 2 2 2 1 Amidohydrolase family CFEM PF05730.6 KEY69017.1 - 3.1e-10 39.7 9.6 7.1e-10 38.5 6.7 1.6 1 0 0 1 1 1 1 CFEM domain SLR1-BP PF07333.7 KEY69017.1 - 6.6 7.0 7.6 0.82 9.9 1.3 2.2 1 1 1 2 2 2 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) GST_C_3 PF14497.1 KEY69018.1 - 1.1e-09 38.6 0.0 2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KEY69018.1 - 4e-05 23.4 0.0 0.00012 21.8 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KEY69018.1 - 0.00056 19.8 0.0 0.0012 18.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KEY69018.1 - 0.0053 16.8 0.0 0.013 15.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain JAB PF01398.16 KEY69019.1 - 5.6e-30 103.4 0.0 8.9e-30 102.7 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KEY69019.1 - 1.8e-07 30.6 0.0 3.4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF4360 PF14273.1 KEY69020.1 - 8.1e-12 45.1 0.7 9.6e-12 44.9 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4449 PF14613.1 KEY69021.1 - 2.6e-67 225.8 1.7 2.6e-67 225.8 1.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) YlqD PF11068.3 KEY69021.1 - 4 7.4 10.3 0.095 12.7 1.3 2.5 2 0 0 2 2 2 0 YlqD protein DUF3818 PF12825.2 KEY69022.1 - 3.8e-34 117.8 0.0 2.8e-26 92.0 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KEY69022.1 - 4.8e-27 94.2 0.0 9.6e-27 93.2 0.0 1.5 1 0 0 1 1 1 1 PX-associated Sigma70_r4_2 PF08281.7 KEY69022.1 - 0.44 10.0 2.4 8.7 5.8 0.0 3.5 4 0 0 4 4 4 0 Sigma-70, region 4 Ribosomal_S19e PF01090.14 KEY69024.1 - 2.2e-56 189.1 0.2 2.5e-56 188.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Prim-Pol PF09250.6 KEY69024.1 - 0.066 13.1 0.1 0.093 12.7 0.1 1.2 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal Zip PF02535.17 KEY69025.1 - 1.1e-54 185.5 4.5 2e-54 184.7 3.1 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3722 PF12519.3 KEY69026.1 - 3.3e-82 275.6 0.1 4.2e-82 275.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 KEY69026.1 - 4.1e-05 23.0 0.1 0.0085 15.4 0.1 2.5 2 0 0 2 2 2 2 Eukaryotic porin LSM PF01423.17 KEY69027.1 - 6.4e-16 57.6 0.2 7.8e-16 57.3 0.2 1.1 1 0 0 1 1 1 1 LSM domain LDB19 PF13002.2 KEY69029.1 - 4.4e-34 117.6 0.5 6.6e-34 117.0 0.3 1.2 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 KEY69029.1 - 3.9e-07 29.9 0.0 8.5e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain HET PF06985.6 KEY69030.1 - 0.023 14.8 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Glyco_hydro_61 PF03443.9 KEY69031.1 - 7.9e-67 225.2 0.1 9.1e-67 225.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CorA PF01544.13 KEY69032.1 - 0.011 14.7 12.1 0.26 10.2 8.4 2.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Sulfate_transp PF00916.15 KEY69032.1 - 0.03 13.3 2.3 0.066 12.2 1.6 1.5 1 0 0 1 1 1 0 Sulfate transporter family Fmp27 PF10344.4 KEY69036.1 - 3.9e-206 686.6 0.0 8.1e-206 685.5 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 KEY69036.1 - 3.7e-164 546.9 1.4 3.7e-164 546.9 1.0 1.8 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 KEY69036.1 - 1.8e-150 501.4 0.2 4.1e-150 500.3 0.1 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 KEY69036.1 - 5.3e-52 175.8 0.0 1.1e-51 174.7 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 KEY69036.1 - 3.7e-48 163.2 0.7 7.4e-48 162.2 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 KEY69036.1 - 1.9e-29 102.1 0.0 5.8e-29 100.5 0.0 1.9 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain CheZ PF04344.8 KEY69036.1 - 0.017 14.7 0.1 0.037 13.6 0.1 1.5 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Gly-zipper_OmpA PF13436.1 KEY69037.1 - 0.22 11.1 0.1 0.22 11.1 0.1 1.9 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 KEY69037.1 - 5.2 7.2 13.0 1.5 9.0 0.2 2.5 2 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide RRM_6 PF14259.1 KEY69038.1 - 3.8e-13 49.2 0.0 6.3e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEY69038.1 - 1.2e-11 44.1 0.0 2.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY69038.1 - 0.00015 21.5 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asp-B-Hydro_N PF05279.6 KEY69038.1 - 3.1 7.6 15.3 4.8 6.9 10.6 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region NUDIX PF00293.23 KEY69039.1 - 3.1e-13 49.5 0.1 7e-13 48.3 0.1 1.6 1 0 0 1 1 1 1 NUDIX domain ABA_GPCR PF12430.3 KEY69040.1 - 4.3e-46 156.5 0.6 9.3e-46 155.4 0.0 1.8 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 KEY69040.1 - 1.4e-20 73.0 0.0 1.5e-19 69.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) Usp PF00582.21 KEY69041.1 - 2.2e-15 57.0 0.0 8.9e-15 55.1 0.0 2.0 2 0 0 2 2 2 1 Universal stress protein family Paf67 PF10255.4 KEY69043.1 - 2.9e-153 510.5 0.9 3.5e-153 510.2 0.6 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 KEY69043.1 - 0.035 14.0 0.0 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat End_beta_barrel PF12195.3 KEY69043.1 - 0.036 13.7 0.0 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 Beta barrel domain of bacteriophage endosialidase GTP_EFTU PF00009.22 KEY69044.1 - 1.4e-53 181.1 0.0 2.3e-53 180.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KEY69044.1 - 1.3e-16 60.1 0.0 3.4e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KEY69044.1 - 2.4e-09 36.9 0.0 5.2e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KEY69044.1 - 3.6e-08 33.4 0.0 9.5e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 KEY69044.1 - 7.7e-05 22.2 0.0 0.0075 15.8 0.0 2.9 3 0 0 3 3 3 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 KEY69044.1 - 0.008 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Pyr_redox_3 PF13738.1 KEY69045.1 - 4.7e-16 59.4 0.0 2.3e-14 53.9 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEY69045.1 - 1.2e-08 34.3 0.0 1.9e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KEY69045.1 - 6.1e-07 28.0 0.0 1.2e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KEY69045.1 - 0.0099 15.7 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DOT1 PF08123.8 KEY69047.1 - 7.4e-72 240.9 0.0 1.4e-71 240.0 0.0 1.4 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 KEY69047.1 - 5.5e-06 26.3 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY69047.1 - 0.00011 22.7 0.4 0.00038 21.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY69047.1 - 0.00024 20.7 0.0 0.00045 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY69047.1 - 0.017 14.4 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 KEY69047.1 - 0.12 12.8 0.0 0.38 11.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Gastrin PF00918.12 KEY69047.1 - 0.26 12.1 1.5 0.4 11.5 0.2 1.9 2 0 0 2 2 2 0 Gastrin/cholecystokinin family ATG16 PF08614.6 KEY69048.1 - 1.9e-44 151.8 17.6 2.1e-44 151.6 12.2 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Filament PF00038.16 KEY69048.1 - 5.6e-06 26.0 6.2 5.6e-06 26.0 4.3 1.9 1 1 1 2 2 2 1 Intermediate filament protein Reo_sigmaC PF04582.7 KEY69048.1 - 0.0043 16.2 3.3 0.041 13.0 2.3 1.9 1 1 0 1 1 1 1 Reovirus sigma C capsid protein SurA_N PF09312.6 KEY69048.1 - 0.0045 16.8 4.3 0.0045 16.8 3.0 1.8 2 0 0 2 2 2 1 SurA N-terminal domain Nup54 PF13874.1 KEY69048.1 - 0.005 16.5 12.3 0.0091 15.6 5.4 2.4 1 1 1 2 2 2 1 Nucleoporin complex subunit 54 TBPIP PF07106.8 KEY69048.1 - 0.025 14.1 13.3 0.023 14.2 7.4 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) BLOC1_2 PF10046.4 KEY69048.1 - 0.032 14.3 4.6 0.16 12.1 1.8 2.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.14 KEY69048.1 - 0.033 12.0 6.6 0.043 11.6 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C4H2 PF10146.4 KEY69048.1 - 0.05 13.6 8.9 0.073 13.0 6.2 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Cep57_CLD_2 PF14197.1 KEY69048.1 - 0.063 13.2 12.0 3.4 7.6 4.4 3.4 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 DUF812 PF05667.6 KEY69048.1 - 0.063 11.7 10.3 0.068 11.6 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FliJ PF02050.11 KEY69048.1 - 0.086 12.8 12.2 0.19 11.8 8.5 1.6 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4201 PF13870.1 KEY69048.1 - 0.11 11.9 13.9 0.13 11.7 8.7 1.8 2 1 0 2 2 1 0 Domain of unknown function (DUF4201) IncA PF04156.9 KEY69048.1 - 0.14 11.7 13.5 1.1 8.7 8.5 2.3 1 1 1 2 2 2 0 IncA protein GAS PF13851.1 KEY69048.1 - 0.15 11.2 16.6 0.35 10.0 10.4 2.0 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Macoilin PF09726.4 KEY69048.1 - 0.16 10.2 10.7 0.19 9.9 7.4 1.1 1 0 0 1 1 1 0 Transmembrane protein TMCO5 PF14992.1 KEY69048.1 - 0.16 11.0 12.4 0.36 9.9 8.6 1.5 1 1 0 1 1 1 0 TMCO5 family YlqD PF11068.3 KEY69048.1 - 0.28 11.2 10.3 0.82 9.7 6.1 2.1 1 1 1 2 2 2 0 YlqD protein DUF2450 PF10475.4 KEY69048.1 - 0.33 9.8 5.3 0.53 9.1 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) FlxA PF14282.1 KEY69048.1 - 0.38 10.7 9.7 0.047 13.6 3.5 1.8 2 0 0 2 2 2 0 FlxA-like protein DUF1664 PF07889.7 KEY69048.1 - 0.48 10.2 5.5 0.24 11.1 2.5 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) HCMV_UL139 PF12507.3 KEY69048.1 - 0.65 10.1 5.5 0.087 12.9 0.9 1.7 2 0 0 2 2 1 0 Human Cytomegalovirus UL139 protein KLRAQ PF10205.4 KEY69048.1 - 0.67 10.0 14.7 28 4.7 0.0 3.3 1 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein SlyX PF04102.7 KEY69048.1 - 1.1 9.6 10.8 4.3 7.7 2.5 3.3 2 1 1 3 3 3 0 SlyX TMF_DNA_bd PF12329.3 KEY69048.1 - 1.2 9.0 18.7 0.82 9.5 0.8 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.4 KEY69048.1 - 1.2 8.0 11.9 1.9 7.3 8.2 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF745 PF05335.8 KEY69048.1 - 1.6 8.2 13.9 5 6.5 9.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF745) APG6 PF04111.7 KEY69048.1 - 2 7.4 14.5 2.8 6.8 8.8 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 KEY69048.1 - 3.2 6.3 14.3 2.9 6.4 8.9 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DivIVA PF05103.8 KEY69048.1 - 4 7.4 14.4 0.77 9.8 5.0 2.3 2 1 0 2 2 2 0 DivIVA protein DUF972 PF06156.8 KEY69048.1 - 4.8 7.5 12.5 15 5.9 1.9 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Vps16_N PF04841.8 KEY69049.1 - 7.3e-86 288.2 0.0 1e-85 287.7 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 KEY69049.1 - 1.4e-76 257.5 0.0 1.9e-76 257.0 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region PQQ_3 PF13570.1 KEY69049.1 - 0.12 12.7 0.0 0.66 10.3 0.0 2.3 2 0 0 2 2 2 0 PQQ-like domain FHA PF00498.21 KEY69050.1 - 2e-15 56.6 0.0 3.8e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 KEY69050.1 - 1.2e-06 28.1 8.2 2.1e-06 27.4 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEY69050.1 - 0.00017 21.6 2.3 0.00032 20.7 1.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KEY69050.1 - 0.014 14.9 7.8 0.025 14.2 5.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 KEY69050.1 - 0.032 13.9 3.7 0.067 12.9 2.6 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.1 KEY69050.1 - 0.044 13.5 5.8 0.076 12.7 4.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEY69050.1 - 0.49 10.4 9.5 0.89 9.6 6.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 KEY69050.1 - 0.68 9.9 3.6 1.3 9.1 2.5 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 KEY69050.1 - 1.9 8.4 6.1 4.1 7.3 4.2 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Peptidase_M16_C PF05193.16 KEY69051.1 - 1.3e-49 168.3 0.0 1e-48 165.4 0.0 2.4 2 1 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KEY69051.1 - 3.9e-43 146.7 0.0 8.3e-41 139.2 0.0 2.4 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) S1 PF00575.18 KEY69053.1 - 1.9e-88 290.6 44.4 9.2e-15 54.5 0.2 13.2 13 0 0 13 13 13 12 S1 RNA binding domain Suf PF05843.9 KEY69053.1 - 0.00021 21.1 4.4 0.17 11.6 0.0 3.2 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) S1_2 PF13509.1 KEY69053.1 - 0.0013 18.6 0.1 24 4.9 0.0 4.6 4 0 0 4 4 4 0 S1 domain PAS_11 PF14598.1 KEY69053.1 - 0.021 14.8 0.0 0.86 9.5 0.0 2.6 2 0 0 2 2 2 0 PAS domain TPR_14 PF13428.1 KEY69053.1 - 0.036 14.6 7.1 72 4.4 0.0 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 KEY69053.1 - 0.26 11.6 7.8 6.5 7.1 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat EXOSC1 PF10447.4 KEY69053.1 - 0.28 11.1 18.4 18 5.3 0.1 8.0 7 2 0 7 7 7 0 Exosome component EXOSC1/CSL4 Fungal_trans PF04082.13 KEY69054.1 - 3e-18 65.6 0.2 5.7e-18 64.7 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY69054.1 - 6.4e-12 45.1 24.4 8.6e-09 35.1 8.0 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain MAP65_ASE1 PF03999.7 KEY69055.1 - 2.8e-72 244.2 6.6 4e-72 243.7 4.6 1.3 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) zf-C4H2 PF10146.4 KEY69055.1 - 0.00067 19.7 1.0 0.00067 19.7 0.7 3.3 2 1 0 2 2 2 1 Zinc finger-containing protein LemA PF04011.7 KEY69055.1 - 0.043 12.9 0.1 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 LemA family DUF948 PF06103.6 KEY69055.1 - 0.4 10.5 1.2 7.8 6.4 0.1 3.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.6 KEY69055.1 - 4.3 4.7 5.6 20 2.5 0.2 2.8 2 1 0 3 3 3 0 Prominin EF-hand_4 PF12763.2 KEY69056.1 - 1.6e-06 27.7 0.0 3.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 KEY69056.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 EF hand Amidase PF01425.16 KEY69057.1 - 1e-70 238.8 0.0 4e-70 236.8 0.0 1.7 1 1 0 1 1 1 1 Amidase peroxidase PF00141.18 KEY69058.1 - 5.6e-28 97.9 0.0 8.4e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Drf_FH1 PF06346.7 KEY69059.1 - 0.064 12.7 7.1 0.067 12.6 4.9 1.0 1 0 0 1 1 1 0 Formin Homology Region 1 DUF2278 PF10042.4 KEY69060.1 - 3.1e-66 223.0 0.1 4.7e-66 222.4 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) LTD PF00932.14 KEY69060.1 - 0.001 19.1 0.1 0.0072 16.3 0.1 2.2 1 1 0 1 1 1 1 Lamin Tail Domain Hemerythrin PF01814.18 KEY69062.1 - 2.8e-15 56.6 5.0 3.6e-15 56.2 3.5 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain TPR_9 PF13371.1 KEY69062.1 - 0.013 15.2 0.2 0.023 14.5 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Occludin_ELL PF07303.8 KEY69062.1 - 0.056 14.1 0.2 12 6.6 0.0 2.4 1 1 1 2 2 2 0 Occludin homology domain Ank_2 PF12796.2 KEY69063.1 - 2.4e-13 50.2 0.0 0.00055 20.2 0.0 3.9 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KEY69063.1 - 1.9e-09 36.8 1.0 0.073 12.9 0.1 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 KEY69063.1 - 3.5e-09 36.0 0.2 0.46 10.8 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 KEY69063.1 - 1.7e-08 34.7 0.2 0.012 16.1 0.0 4.1 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY69063.1 - 0.0025 18.0 0.5 1.9 8.8 0.1 4.2 3 1 1 4 4 4 1 Ankyrin repeats (many copies) eIF-3c_N PF05470.7 KEY69064.1 - 2.1e-175 584.2 25.6 3.5e-143 477.8 0.6 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 KEY69064.1 - 9.2e-14 51.6 0.0 3.4e-13 49.8 0.0 2.1 1 0 0 1 1 1 1 PCI domain U1snRNP70_N PF12220.3 KEY69064.1 - 7.8 6.8 11.5 1.2 9.4 1.6 3.2 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Fe-S_biosyn PF01521.15 KEY69065.1 - 6e-11 42.2 0.0 1e-08 35.1 0.0 2.4 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Ribosomal_L30_N PF08079.7 KEY69066.1 - 2.7e-23 81.7 17.8 4.9e-23 80.9 12.3 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 KEY69066.1 - 1.2e-20 72.7 3.0 1.3e-20 72.7 0.9 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_S11 PF00411.14 KEY69067.1 - 1.6e-40 137.7 0.6 1.9e-40 137.4 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 KEY69067.1 - 0.092 11.6 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) SNF2_N PF00176.18 KEY69068.1 - 2.8e-71 239.7 0.1 1e-70 237.9 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEY69068.1 - 2.6e-14 52.8 0.0 5.9e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ApbA_C PF08546.6 KEY69069.1 - 3.3e-26 91.7 0.0 6.2e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KEY69069.1 - 1.8e-19 69.6 0.0 8.3e-19 67.5 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA RBM39linker PF15519.1 KEY69069.1 - 0.0095 16.1 0.1 0.026 14.8 0.1 1.7 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein Myb_DNA-bind_6 PF13921.1 KEY69070.1 - 2.9e-16 59.2 0.1 1.6e-08 34.4 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KEY69070.1 - 3.1e-13 49.5 0.3 1.8e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_32 PF13565.1 KEY69070.1 - 0.037 14.8 0.3 0.11 13.2 0.1 2.0 1 1 0 1 1 1 0 Homeodomain-like domain DUF4085 PF13315.1 KEY69070.1 - 0.052 12.9 0.1 0.07 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) Sigma70_r4_2 PF08281.7 KEY69070.1 - 0.064 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 DUF1446 PF07287.6 KEY69070.1 - 0.12 10.7 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1446) HTH_AsnC-type PF13404.1 KEY69070.1 - 0.14 11.6 0.1 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Metallophos PF00149.23 KEY69071.1 - 6.9e-06 25.5 0.1 1e-05 25.0 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.20 KEY69072.1 - 3.7e-16 59.0 0.0 6.5e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY69072.1 - 4.3e-05 22.7 0.0 0.00038 19.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KEY69073.1 - 4.2e-27 94.9 0.0 6.9e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HET PF06985.6 KEY69073.1 - 1.5e-20 73.7 0.0 3e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase_Tyr PF07714.12 KEY69073.1 - 2.8e-15 56.0 0.0 4.4e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KEY69073.1 - 0.62 8.7 0.0 1 8.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Zn_clus PF00172.13 KEY69074.1 - 4.3e-05 23.3 3.5 4.3e-05 23.3 2.4 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NB PF04159.8 KEY69074.1 - 0.073 12.8 0.3 0.17 11.6 0.2 1.6 1 0 0 1 1 1 0 NB glycoprotein GST_N_3 PF13417.1 KEY69075.1 - 2e-15 56.7 0.0 3.3e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KEY69075.1 - 4.6e-12 45.9 0.0 9.8e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEY69075.1 - 1.2e-10 41.2 0.0 2e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KEY69075.1 - 6.9e-10 38.7 0.0 1.1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KEY69075.1 - 9e-07 28.7 0.1 1.6e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEY69075.1 - 0.0093 16.4 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NmrA PF05368.8 KEY69076.1 - 3.3e-23 82.1 0.0 4.2e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY69076.1 - 3.7e-13 49.8 0.1 5.6e-13 49.2 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KEY69076.1 - 7.1e-07 28.5 0.0 9.6e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 KEY69076.1 - 0.00019 20.9 0.0 0.00036 20.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KEY69076.1 - 0.001 19.3 0.0 0.0033 17.7 0.0 1.9 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KEY69076.1 - 0.0062 15.2 0.0 0.017 13.8 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KEY69076.1 - 0.013 14.4 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein DapB_N PF01113.15 KEY69076.1 - 0.017 15.0 0.0 0.039 13.8 0.0 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 KEY69076.1 - 0.12 11.2 0.0 0.73 8.6 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.13 KEY69077.1 - 8.3e-06 24.8 0.3 5e-05 22.2 0.2 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain AA_permease PF00324.16 KEY69080.1 - 2.8e-64 217.1 27.7 8.1e-64 215.7 19.2 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEY69080.1 - 4.7e-29 101.1 25.5 6.7e-29 100.6 17.7 1.2 1 0 0 1 1 1 1 Amino acid permease ADH_N PF08240.7 KEY69080.1 - 4e-21 74.8 0.2 4e-21 74.8 0.1 2.1 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY69080.1 - 1.4e-17 63.4 0.0 3e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KEY69080.1 - 0.11 11.6 0.1 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_M36 PF02128.10 KEY69081.1 - 3.9e-131 437.3 2.7 4.9e-131 437.0 1.9 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 KEY69081.1 - 3.1e-13 48.9 2.1 3.9e-13 48.6 0.5 1.9 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_MA_2 PF13485.1 KEY69081.1 - 0.0021 18.1 0.2 0.0045 17.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily PLDc PF00614.17 KEY69081.1 - 0.058 13.2 0.0 0.22 11.3 0.0 2.1 1 0 0 1 1 1 0 Phospholipase D Active site motif Acyl_transf_1 PF00698.16 KEY69082.1 - 8.8e-15 54.8 0.1 3.5e-14 52.8 0.1 1.7 1 1 0 1 1 1 1 Acyl transferase domain Tannase PF07519.6 KEY69083.1 - 6.6e-21 74.5 0.0 6.8e-21 74.5 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Phlebovirus_G2 PF07245.6 KEY69084.1 - 0.16 10.2 0.0 0.22 9.7 0.0 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 Zn_clus PF00172.13 KEY69085.1 - 2e-11 43.5 12.0 4.9e-11 42.3 8.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY69085.1 - 1.5e-09 37.1 0.0 8.9e-08 31.3 0.0 2.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain ADH_zinc_N PF00107.21 KEY69086.1 - 6.3e-11 41.9 0.2 1.4e-10 40.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY69086.1 - 3.9e-10 40.7 0.0 2.9e-09 37.8 0.0 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY69086.1 - 0.00051 19.7 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Eno-Rase_NADH_b PF12242.3 KEY69086.1 - 0.085 12.6 0.5 8.7 6.2 0.0 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase zf-H2C2_2 PF13465.1 KEY69087.1 - 1.2e-20 72.7 31.5 5.5e-08 32.7 0.4 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 KEY69087.1 - 1.6e-20 72.1 31.0 1.1e-05 25.5 0.1 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY69087.1 - 1.5e-11 43.7 26.1 0.00057 20.0 1.2 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 KEY69087.1 - 0.012 15.8 11.4 0.02 15.0 0.5 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 KEY69087.1 - 0.013 15.8 14.1 0.024 15.0 1.6 3.2 1 1 2 3 3 3 0 TRAF-type zinc finger Ogr_Delta PF04606.7 KEY69087.1 - 0.055 13.1 2.9 5.5 6.7 0.1 2.9 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_jaz PF12171.3 KEY69087.1 - 0.064 13.4 13.4 1.5 9.0 0.3 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding CHORD PF04968.7 KEY69087.1 - 8.3 6.7 16.9 3.9 7.7 0.2 4.3 1 1 3 4 4 4 0 CHORD Peptidase_M41 PF01434.13 KEY69088.1 - 7.3e-65 218.4 2.6 1.3e-64 217.5 1.5 1.7 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 KEY69088.1 - 3.3e-44 150.2 0.0 7.8e-44 149.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEY69088.1 - 5.1e-07 29.5 0.1 4e-06 26.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEY69088.1 - 5.7e-07 29.7 0.9 0.00013 22.1 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KEY69088.1 - 2e-05 25.3 0.0 6e-05 23.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 KEY69088.1 - 7.4e-05 21.6 0.0 0.00015 20.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 KEY69088.1 - 0.00011 22.2 3.5 0.00043 20.3 0.1 3.4 4 1 0 4 4 4 1 AAA ATPase domain RuvB_N PF05496.7 KEY69088.1 - 0.00041 19.4 0.0 0.00087 18.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KEY69088.1 - 0.00065 19.4 0.2 0.0029 17.3 0.2 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KEY69088.1 - 0.0013 18.1 0.6 0.23 10.8 0.2 2.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KEY69088.1 - 0.0015 18.3 0.1 0.0053 16.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 KEY69088.1 - 0.0021 17.5 0.1 0.0053 16.1 0.1 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.13 KEY69088.1 - 0.0023 17.5 0.0 0.0054 16.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial dnaA protein AAA_14 PF13173.1 KEY69088.1 - 0.005 16.7 0.0 0.016 15.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KEY69088.1 - 0.0096 15.0 3.1 0.02 14.0 0.2 2.7 2 1 1 3 3 3 1 Zeta toxin AAA_28 PF13521.1 KEY69088.1 - 0.016 15.1 0.0 0.044 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KEY69088.1 - 0.019 14.1 1.1 0.035 13.2 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KEY69088.1 - 0.049 13.2 0.2 1 9.0 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_2 PF07724.9 KEY69088.1 - 0.051 13.4 0.0 0.29 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 KEY69088.1 - 0.078 13.2 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KEY69088.1 - 0.085 12.9 0.0 0.38 10.7 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 KEY69088.1 - 0.17 11.0 1.4 0.27 10.4 0.3 1.7 2 0 0 2 2 2 0 PhoH-like protein Epimerase PF01370.16 KEY69089.1 - 5.1e-21 75.1 0.0 9.1e-21 74.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEY69089.1 - 3.4e-16 58.7 0.0 5e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KEY69089.1 - 1.9e-13 50.7 0.9 3.8e-13 49.8 0.6 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KEY69089.1 - 1.5e-11 43.7 0.0 3.4e-11 42.5 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KEY69089.1 - 1.2e-09 38.3 0.4 3.1e-09 36.9 0.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KEY69089.1 - 1.1e-07 31.1 0.0 1.7e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KEY69089.1 - 5.2e-06 26.2 0.1 1e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 KEY69089.1 - 2.3e-05 23.7 0.1 5.3e-05 22.5 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family F420_oxidored PF03807.12 KEY69089.1 - 0.00029 21.2 0.0 0.00065 20.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 KEY69089.1 - 0.0029 16.5 0.1 0.0057 15.5 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain Retro_M PF02813.9 KEY69089.1 - 0.016 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral M domain NAD_binding_2 PF03446.10 KEY69089.1 - 0.11 12.3 0.1 6.1 6.6 0.0 2.2 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Zeta_toxin PF06414.7 KEY69089.1 - 0.11 11.5 0.0 0.3 10.1 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin DUF4448 PF14610.1 KEY69090.1 - 0.00028 20.4 0.0 0.0025 17.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 KEY69090.1 - 0.082 12.2 1.5 0.18 11.1 1.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain adh_short PF00106.20 KEY69092.1 - 4.8e-29 101.4 0.8 6.8e-29 100.9 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY69092.1 - 1.7e-25 90.1 0.0 2.1e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY69092.1 - 2.2e-12 47.0 0.7 6.1e-12 45.5 0.5 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY69092.1 - 4.7e-05 22.9 0.0 7.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ORC6 PF05460.8 KEY69093.1 - 1.3e-34 119.9 9.6 2.1e-33 115.8 6.6 2.0 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) adh_short PF00106.20 KEY69094.1 - 3e-19 69.5 0.1 5.5e-19 68.6 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY69094.1 - 5e-08 32.8 0.1 8.6e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 KR domain EF-hand_1 PF00036.27 KEY69095.1 - 0.00085 18.4 0.2 0.0015 17.7 0.1 1.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KEY69095.1 - 0.0025 17.5 0.1 0.1 12.5 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 KEY69095.1 - 0.0072 15.9 0.1 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 KEY69095.1 - 0.0077 16.3 1.5 0.028 14.5 0.0 1.9 1 1 1 2 2 2 2 EF-hand domain pair Met_10 PF02475.11 KEY69096.1 - 3e-05 23.7 0.0 5.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 KEY69096.1 - 0.0063 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Metallophos PF00149.23 KEY69097.1 - 1.1e-37 129.3 0.0 7e-37 126.7 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase NOSIC PF08060.8 KEY69097.1 - 0.089 12.6 0.0 0.32 10.8 0.0 1.9 2 0 0 2 2 2 0 NOSIC (NUC001) domain Smg4_UPF3 PF03467.10 KEY69098.1 - 9.3e-32 110.4 0.0 9.3e-32 110.4 0.0 2.1 2 0 0 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.17 KEY69098.1 - 9.6e-08 31.5 0.0 1.6e-06 27.5 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY69098.1 - 8.4e-06 25.6 0.0 4.9e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY69098.1 - 0.008 16.0 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANTAR PF03861.9 KEY69098.1 - 0.034 13.7 1.6 0.17 11.4 0.9 2.1 2 0 0 2 2 2 0 ANTAR domain Pyridox_oxidase PF01243.15 KEY69099.1 - 0.0021 18.0 0.0 0.0072 16.3 0.0 2.0 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase IncA PF04156.9 KEY69100.1 - 2.5e-05 23.9 6.5 2.5e-05 23.9 4.5 2.1 2 0 0 2 2 2 1 IncA protein DUF3416 PF11896.3 KEY69100.1 - 0.00056 19.9 2.0 0.0009 19.2 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3416) bZIP_1 PF00170.16 KEY69100.1 - 0.0043 16.9 3.1 0.0043 16.9 2.1 3.3 3 1 1 4 4 3 2 bZIP transcription factor Mt_ATP-synt_D PF05873.7 KEY69100.1 - 0.0088 15.6 2.9 0.011 15.3 1.1 1.8 1 1 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DivIC PF04977.10 KEY69100.1 - 0.013 14.9 24.5 0.038 13.4 3.9 3.8 2 1 2 4 4 4 0 Septum formation initiator Nup54 PF13874.1 KEY69100.1 - 0.017 14.8 8.3 0.035 13.7 5.8 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Laminin_II PF06009.7 KEY69100.1 - 0.079 12.7 11.1 0.11 12.3 5.7 2.1 1 1 1 2 2 2 0 Laminin Domain II DUF1664 PF07889.7 KEY69100.1 - 0.69 9.7 8.0 0.99 9.2 5.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TSC22 PF01166.13 KEY69100.1 - 1 9.3 11.4 0.76 9.7 1.5 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family UPF0242 PF06785.6 KEY69100.1 - 1.1 7.8 8.7 1.7 7.2 6.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) TMPIT PF07851.8 KEY69100.1 - 1.4 7.9 7.7 2.3 7.1 5.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein Sec8_exocyst PF04048.9 KEY69100.1 - 2 8.0 10.0 7.8 6.1 6.8 2.0 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain DUF4239 PF14023.1 KEY69100.1 - 3.1 7.1 6.3 1.8 7.8 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) ADIP PF11559.3 KEY69100.1 - 3.6 7.4 30.2 0.056 13.3 11.0 3.0 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2353 PF09789.4 KEY69100.1 - 4.7 6.3 26.3 18 4.4 17.8 2.2 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Adeno_PIX PF03955.9 KEY69100.1 - 5.6 7.5 7.8 20 5.7 1.1 2.4 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) GLE1 PF07817.8 KEY69100.1 - 5.7 5.7 7.0 0.95 8.3 1.4 1.9 1 1 1 2 2 2 0 GLE1-like protein DUF3141 PF11339.3 KEY69100.1 - 7 4.8 6.2 9.1 4.4 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) TPR_MLP1_2 PF07926.7 KEY69100.1 - 7.9 6.2 24.6 0.28 10.9 11.8 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Gly_transf_sug PF04488.10 KEY69102.1 - 1.8e-14 53.9 0.2 3.4e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KEY69102.1 - 7.4e-06 25.3 0.0 1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 KEY69102.1 - 0.00084 17.9 0.1 0.0015 17.1 0.1 1.3 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Rax2 PF12768.2 KEY69103.1 - 7.2e-05 22.1 0.0 9.9e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Cortical protein marker for cell polarity SKG6 PF08693.5 KEY69103.1 - 0.0026 17.0 1.5 0.0066 15.7 1.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1517 PF07466.6 KEY69103.1 - 0.018 14.0 1.4 0.026 13.5 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) EphA2_TM PF14575.1 KEY69103.1 - 0.058 13.7 0.3 0.21 11.9 0.2 1.9 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Gram_pos_anchor PF00746.16 KEY69103.1 - 0.27 11.1 2.6 0.56 10.0 1.8 1.5 1 0 0 1 1 1 0 Gram positive anchor CTD PF12815.2 KEY69103.1 - 2.5 8.5 12.3 1.2 9.5 3.1 2.1 2 0 0 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 RAP1 PF07218.6 KEY69103.1 - 3.6 5.5 4.7 4 5.4 3.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RTA1 PF04479.8 KEY69105.1 - 1.3e-36 126.2 9.6 1.7e-36 125.8 6.6 1.1 1 0 0 1 1 1 1 RTA1 like protein PAP2 PF01569.16 KEY69105.1 - 0.1 12.2 0.2 0.1 12.2 0.1 2.7 3 0 0 3 3 3 0 PAP2 superfamily Nop14 PF04147.7 KEY69106.1 - 6.5 4.5 6.1 7.3 4.3 4.2 1.0 1 0 0 1 1 1 0 Nop14-like family ketoacyl-synt PF00109.21 KEY69108.1 - 8.7e-63 212.1 0.2 5.2e-62 209.6 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KEY69108.1 - 2.1e-53 180.7 2.2 3.5e-53 179.9 0.0 2.5 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 KEY69108.1 - 5.8e-53 180.2 0.0 9.7e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KEY69108.1 - 1.7e-51 175.1 0.0 2.9e-51 174.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KEY69108.1 - 6.2e-43 146.6 0.3 1.7e-41 141.9 0.0 2.8 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KEY69108.1 - 1.6e-37 127.9 0.0 6.6e-37 125.9 0.0 2.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KEY69108.1 - 4e-19 68.4 0.1 1.1e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY69108.1 - 3.1e-10 41.0 0.0 1.3e-09 38.9 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY69108.1 - 5.1e-08 32.6 0.0 1.3e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KEY69108.1 - 0.0019 18.4 0.2 0.0093 16.2 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site FAD_binding_4 PF01565.18 KEY69109.1 - 3e-24 85.0 1.1 5.4e-24 84.2 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY69109.1 - 2.5e-08 33.6 0.1 4.6e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 KEY69110.1 - 1.1e-46 159.3 0.0 1.7e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KEY69111.1 - 4.6e-59 200.1 0.0 6.2e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cupin_2 PF07883.6 KEY69113.1 - 6.9e-07 28.6 0.0 2.4e-06 26.9 0.0 2.0 2 1 0 2 2 2 1 Cupin domain adh_short PF00106.20 KEY69114.1 - 6.7e-16 58.6 0.0 8.2e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY69114.1 - 1.8e-05 24.6 0.0 2.1e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY69114.1 - 0.0011 18.6 0.1 0.0016 18.1 0.1 1.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KEY69114.1 - 0.0036 17.3 0.0 0.0055 16.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEY69114.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KEY69115.1 - 3.4e-27 95.7 0.1 4.1e-27 95.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEY69115.1 - 1e-19 71.0 1.0 1.8e-19 70.2 0.7 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY69115.1 - 5.9e-08 32.5 0.3 1.5e-07 31.2 0.2 1.6 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 KEY69116.1 - 4.7e-13 49.3 0.0 7e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY69116.1 - 4.9e-09 36.1 0.0 8.9e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY69116.1 - 0.00023 21.0 0.0 0.00034 20.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pyridox_oxidase PF01243.15 KEY69118.1 - 1.7e-07 31.1 0.0 0.0028 17.6 0.0 2.5 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.19 KEY69118.1 - 0.0012 18.9 0.0 0.046 13.8 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KEY69118.1 - 0.0051 17.3 0.0 0.0095 16.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_9 PF08021.6 KEY69118.1 - 0.022 14.7 0.1 0.047 13.6 0.1 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain T2SF PF00482.18 KEY69119.1 - 0.066 13.1 1.0 0.15 12.0 0.7 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF202 PF02656.10 KEY69119.1 - 0.34 11.1 4.6 0.97 9.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Pkinase PF00069.20 KEY69120.1 - 0.0003 20.0 0.0 0.0034 16.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Sigma70_ner PF04546.8 KEY69121.1 - 0.28 10.7 2.3 0.46 10.0 1.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 KEY69121.1 - 0.99 9.7 5.9 1.6 9.0 4.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 KEY69121.1 - 3.8 6.1 8.8 5.9 5.5 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Glyoxalase PF00903.20 KEY69123.1 - 5e-40 136.4 0.4 1.1e-19 70.6 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KEY69123.1 - 5e-33 113.9 0.1 2.1e-16 60.4 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KEY69123.1 - 2.5e-18 66.0 0.1 4.1e-08 33.1 0.0 3.6 2 2 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KEY69123.1 - 9.8e-06 25.5 0.0 0.13 12.1 0.0 3.3 1 1 2 3 3 3 3 Glyoxalase-like domain MoaF PF10703.4 KEY69123.1 - 0.048 12.7 0.0 1.7 7.6 0.0 2.1 2 0 0 2 2 2 0 Molybdenum cofactor biosynthesis protein F DUF21 PF01595.15 KEY69124.1 - 3.6e-33 114.3 0.1 5.3e-33 113.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KEY69124.1 - 6.3e-09 35.4 1.2 0.0037 17.0 0.0 2.9 2 0 0 2 2 2 2 CBS domain Lactonase PF10282.4 KEY69125.1 - 9e-14 51.3 0.0 1.7e-13 50.3 0.0 1.6 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Dioxygenase_C PF00775.16 KEY69126.1 - 1.1e-49 168.1 0.0 1.6e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KEY69126.1 - 1e-13 51.0 0.1 1.8e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KEY69126.1 - 0.011 15.7 0.0 0.044 13.8 0.0 2.1 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Drf_GBD PF06371.8 KEY69127.1 - 1.3e-13 50.7 3.4 3.4e-12 46.1 2.4 2.2 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Methyltransf_6 PF03737.10 KEY69128.1 - 1.5e-18 67.0 0.3 2.4e-18 66.4 0.1 1.4 2 0 0 2 2 2 1 Demethylmenaquinone methyltransferase WWbp PF10349.4 KEY69129.1 - 1.3e-13 51.8 0.8 2.2e-13 51.1 0.5 1.4 1 0 0 1 1 1 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 KEY69129.1 - 0.005 16.6 0.0 0.014 15.2 0.0 1.7 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 KEY69129.1 - 0.021 14.3 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 GRAM domain bPH_3 PF14470.1 KEY69129.1 - 0.057 13.6 0.0 0.091 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial PH domain UCR_hinge PF02320.11 KEY69130.1 - 1.7e-27 95.1 9.7 4.1e-27 93.9 6.7 1.7 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein GET2 PF08690.5 KEY69130.1 - 0.026 13.7 4.2 0.034 13.3 2.9 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 CDC45 PF02724.9 KEY69130.1 - 0.17 9.8 12.6 0.18 9.7 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Phyto_Pns9_10 PF05878.6 KEY69130.1 - 0.32 9.9 8.8 0.39 9.6 6.1 1.3 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Mem_trans PF03547.13 KEY69130.1 - 0.87 7.8 3.5 0.89 7.7 2.4 1.1 1 0 0 1 1 1 0 Membrane transport protein DDHD PF02862.12 KEY69130.1 - 1.1 9.0 9.6 1.4 8.6 6.6 1.3 1 0 0 1 1 1 0 DDHD domain Ycf1 PF05758.7 KEY69130.1 - 1.5 6.4 11.3 1.5 6.4 7.8 1.0 1 0 0 1 1 1 0 Ycf1 DUF913 PF06025.7 KEY69130.1 - 1.5 7.5 6.8 1.7 7.3 4.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF853 PF05872.7 KEY69130.1 - 1.7 6.9 6.6 1.9 6.7 4.6 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) SAPS PF04499.10 KEY69130.1 - 1.8 7.1 10.7 2 6.9 7.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Daxx PF03344.10 KEY69130.1 - 2 6.7 26.9 2.4 6.5 18.7 1.1 1 0 0 1 1 1 0 Daxx Family DUF4045 PF13254.1 KEY69130.1 - 2 7.5 12.3 2.2 7.4 8.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Senescence_reg PF04520.8 KEY69130.1 - 2 8.8 11.5 1.8 9.0 7.4 1.4 1 1 0 1 1 1 0 Senescence regulator Peptidase_S64 PF08192.6 KEY69130.1 - 2.2 6.4 4.9 2.3 6.4 3.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF2413 PF10310.4 KEY69130.1 - 2.3 6.9 15.7 2.7 6.7 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Astro_capsid PF03115.9 KEY69130.1 - 2.5 6.2 7.0 2.5 6.2 4.8 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Tim54 PF11711.3 KEY69130.1 - 2.8 6.4 13.9 3.4 6.1 9.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DHHW PF14286.1 KEY69130.1 - 4.7 6.4 11.7 5.4 6.2 8.1 1.1 1 0 0 1 1 1 0 DHHW protein Nop14 PF04147.7 KEY69130.1 - 6 4.6 24.9 6.9 4.4 17.2 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 KEY69130.1 - 7.3 5.5 21.3 8.9 5.2 14.8 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.7 KEY69130.1 - 7.5 5.7 22.7 9.1 5.4 15.7 1.1 1 0 0 1 1 1 0 SDA1 HSP70 PF00012.15 KEY69130.1 - 7.6 4.3 13.6 8.6 4.1 9.4 1.0 1 0 0 1 1 1 0 Hsp70 protein Hid1 PF12722.2 KEY69130.1 - 8.5 3.9 9.2 8.8 3.8 6.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MFS_1 PF07690.11 KEY69131.1 - 1.7e-23 82.9 38.9 1.7e-23 82.9 26.9 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KEY69131.1 - 0.0072 16.0 0.2 0.026 14.2 0.1 2.0 1 0 0 1 1 1 1 MFS_1 like family adh_short PF00106.20 KEY69132.1 - 0.0024 17.8 0.1 0.0067 16.3 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KH_1 PF00013.24 KEY69133.1 - 2.4e-94 308.9 29.0 8e-15 54.2 0.5 13.8 14 0 0 14 14 14 10 KH domain KH_3 PF13014.1 KEY69133.1 - 1.6e-70 231.7 16.3 3.4e-10 39.3 0.1 12.9 13 0 0 13 13 13 9 KH domain SLS PF14611.1 KEY69133.1 - 1.2e-12 47.7 1.2 0.024 14.0 0.0 6.3 5 1 2 7 7 7 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 KEY69133.1 - 2.6e-12 46.1 29.6 0.012 15.1 0.1 8.2 8 1 0 9 9 9 5 KH domain KH_4 PF13083.1 KEY69133.1 - 0.00061 19.3 12.0 0.27 10.9 0.1 5.9 7 0 0 7 7 7 2 KH domain Pkinase PF00069.20 KEY69134.1 - 2.9e-72 242.9 0.0 4.3e-72 242.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY69134.1 - 1.2e-46 158.9 0.0 1.8e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KEY69134.1 - 7.4e-18 64.7 0.0 2.8e-17 62.8 0.0 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 KEY69134.1 - 2.3e-08 33.3 0.0 3.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEY69134.1 - 0.044 13.5 0.0 0.044 13.5 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KEY69134.1 - 0.062 12.3 0.1 0.24 10.4 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.7 KEY69134.1 - 0.22 10.7 0.0 0.44 9.7 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain adh_short PF00106.20 KEY69135.1 - 5.1e-31 107.8 0.7 6.9e-31 107.4 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY69135.1 - 1.8e-27 96.7 0.4 2.3e-27 96.3 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY69135.1 - 2.1e-12 47.0 0.2 3e-12 46.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY69135.1 - 1.3e-06 28.0 0.1 1e-05 25.1 0.1 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PA PF02225.17 KEY69135.1 - 1.5e-05 24.6 0.4 4.6e-05 23.0 0.1 2.0 2 0 0 2 2 2 1 PA domain Polysacc_synt_2 PF02719.10 KEY69135.1 - 0.012 14.5 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.1 KEY69135.1 - 0.073 13.4 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ARID PF01388.16 KEY69136.1 - 4.8e-18 64.8 0.0 1.3e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain CTNNBL PF08216.6 KEY69136.1 - 0.091 12.3 0.9 0.35 10.4 0.0 2.4 3 0 0 3 3 3 0 Catenin-beta-like, Arm-motif containing nuclear RIC3 PF15361.1 KEY69136.1 - 2.9 8.1 9.1 8.6 6.5 6.3 1.8 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF500 PF04366.7 KEY69138.1 - 2.9e-44 149.5 0.3 4.8e-44 148.8 0.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 KEY69138.1 - 3.3e-15 55.1 0.3 1.3e-14 53.2 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KEY69138.1 - 1e-14 53.7 0.1 2.1e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KEY69138.1 - 5e-13 48.4 0.0 9.8e-13 47.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SNARE PF05739.14 KEY69139.1 - 0.0034 17.0 0.1 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 SNARE domain ArfGap PF01412.13 KEY69140.1 - 9.2e-41 138.3 0.6 1.3e-40 137.7 0.4 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SelR PF01641.13 KEY69141.1 - 2.2e-49 166.2 0.1 2.8e-49 165.9 0.1 1.1 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 KEY69141.1 - 0.006 16.3 0.8 0.81 9.5 0.1 2.3 2 0 0 2 2 2 2 Double zinc ribbon DUF2296 PF10058.4 KEY69141.1 - 0.039 13.6 1.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Yippee-Mis18 PF03226.9 KEY69141.1 - 0.074 13.1 0.7 0.37 10.8 0.5 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TF_Zn_Ribbon PF08271.7 KEY69141.1 - 0.46 9.8 2.6 1.2 8.4 0.2 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Thiolase_N PF00108.18 KEY69142.1 - 7.8e-78 261.0 2.9 1.1e-77 260.6 2.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KEY69142.1 - 1.5e-41 140.6 0.2 3.3e-41 139.5 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 KEY69142.1 - 0.0013 18.7 0.0 0.0043 17.0 0.0 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal OCD_Mu_crystall PF02423.10 KEY69143.1 - 2.9e-14 52.5 0.1 4.6e-08 32.1 0.0 3.0 3 0 0 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family DUF4147 PF13660.1 KEY69143.1 - 0.02 14.0 0.0 0.043 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Cg6151-P PF10233.4 KEY69144.1 - 4.5e-35 120.0 13.7 5.3e-35 119.7 9.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P LMF1 PF06762.9 KEY69144.1 - 0.18 10.5 4.3 0.23 10.2 3.0 1.2 1 0 0 1 1 1 0 Lipase maturation factor EAV_GS PF01309.13 KEY69144.1 - 0.4 10.1 3.2 0.17 11.4 0.4 1.6 1 1 1 2 2 2 0 Equine arteritis virus small envelope glycoprotein PRA1 PF03208.14 KEY69144.1 - 1.8 7.9 15.2 13 5.0 10.6 1.9 1 1 0 1 1 1 0 PRA1 family protein Cytochrom_B558a PF05038.8 KEY69144.1 - 2.5 7.7 8.3 7.5 6.1 5.3 2.1 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit DUF3210 PF11489.3 KEY69145.1 - 1.2e-193 645.7 70.7 1.2e-193 645.7 49.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3210) Dna2 PF08696.6 KEY69147.1 - 8.1e-72 240.9 0.8 8.1e-72 240.9 0.6 2.4 4 0 0 4 4 4 1 DNA replication factor Dna2 AAA_12 PF13087.1 KEY69147.1 - 8.1e-52 175.5 0.2 2.1e-51 174.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KEY69147.1 - 2e-40 138.8 0.2 4.5e-19 68.9 0.0 2.9 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 KEY69147.1 - 1.2e-14 54.3 0.0 4.5e-14 52.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.12 KEY69147.1 - 1.3e-12 47.9 0.7 1.8e-10 40.9 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF83 AAA_19 PF13245.1 KEY69147.1 - 1.7e-10 40.5 0.3 5.7e-10 38.8 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain PDDEXK_1 PF12705.2 KEY69147.1 - 2.3e-09 36.9 0.1 4.9e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 KEY69147.1 - 1.2e-07 31.4 0.2 0.22 11.0 0.0 3.7 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DUF911 PF06023.7 KEY69147.1 - 6.2e-05 22.3 0.9 0.00015 21.1 0.6 1.5 1 1 0 1 1 1 1 Archaeal protein of unknown function (DUF911) Helicase_RecD PF05127.9 KEY69147.1 - 0.00012 21.7 0.0 0.00051 19.7 0.0 2.1 1 1 0 1 1 1 1 Helicase MobB PF03205.9 KEY69147.1 - 0.00016 21.3 1.8 0.00041 20.0 0.2 2.5 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B PIF1 PF05970.9 KEY69147.1 - 0.00026 20.0 0.4 0.042 12.7 0.0 2.5 3 0 0 3 3 3 1 PIF1-like helicase SRP54 PF00448.17 KEY69147.1 - 0.00066 19.1 1.1 0.0017 17.8 0.1 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 KEY69147.1 - 0.00099 19.1 1.2 0.018 15.0 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain CbiA PF01656.18 KEY69147.1 - 0.0018 17.6 0.0 0.0071 15.7 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.4 KEY69147.1 - 0.0034 16.3 0.0 0.0077 15.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 KEY69147.1 - 0.0076 15.6 0.0 0.043 13.2 0.0 2.3 2 0 0 2 2 1 1 AAA domain UvrD-helicase PF00580.16 KEY69147.1 - 0.012 14.9 1.5 0.017 14.4 0.1 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 KEY69147.1 - 0.021 14.9 0.0 0.25 11.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KEY69147.1 - 0.022 13.7 0.1 0.045 12.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Miro PF08477.8 KEY69147.1 - 0.022 15.2 0.0 0.15 12.5 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 KEY69147.1 - 0.043 13.3 0.1 2.5 7.6 0.0 3.4 4 0 0 4 4 3 0 AAA domain NTPase_1 PF03266.10 KEY69147.1 - 0.078 12.6 0.8 0.23 11.1 0.2 2.1 2 0 0 2 2 1 0 NTPase AAA PF00004.24 KEY69147.1 - 0.084 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 KEY69147.1 - 0.42 10.3 2.8 0.41 10.4 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 ESSS PF10183.4 KEY69148.1 - 5.6e-19 68.4 0.2 6.7e-19 68.2 0.1 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PepSY_2 PF13670.1 KEY69148.1 - 0.0086 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain Aminotran_4 PF01063.14 KEY69149.1 - 7.9e-31 107.3 0.0 1.2e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV Pkinase PF00069.20 KEY69150.1 - 3.4e-17 62.4 0.0 7.2e-17 61.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY69150.1 - 4.7e-10 38.9 0.0 2.9e-09 36.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Mito_fiss_reg PF05308.6 KEY69151.1 - 0.033 13.5 0.9 0.035 13.4 0.7 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator SIR2 PF02146.12 KEY69152.1 - 2.8e-58 196.5 0.0 5.3e-58 195.6 0.0 1.5 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 KEY69152.1 - 0.012 15.1 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 KEY69152.1 - 0.023 14.4 0.1 4.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain IFT43 PF15305.1 KEY69152.1 - 0.49 10.3 3.6 0.22 11.5 0.3 1.9 2 0 0 2 2 2 0 Intraflagellar transport protein 43 E1-E2_ATPase PF00122.15 KEY69153.1 - 1.2e-53 181.5 1.6 1.2e-53 181.5 1.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEY69153.1 - 9.3e-41 139.3 7.2 9.3e-41 139.3 5.0 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEY69153.1 - 5.1e-29 102.2 0.0 3.6e-28 99.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEY69153.1 - 4.3e-17 61.8 0.0 9.5e-17 60.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEY69153.1 - 6.6e-16 59.0 0.0 1.2e-15 58.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEY69153.1 - 2.3e-06 27.3 1.1 5.2e-06 26.2 0.5 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEY69153.1 - 1.6e-05 24.2 0.0 4.6e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus TTL PF03133.10 KEY69154.1 - 7.1e-57 192.5 0.0 1.1e-56 191.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 KEY69154.1 - 6.8e-45 152.8 0.0 9.5e-45 152.3 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.1 KEY69154.1 - 4.8e-05 22.2 0.0 0.00018 20.3 0.0 1.8 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 KEY69154.1 - 0.00092 18.9 0.1 0.15 11.7 0.0 2.7 3 0 0 3 3 3 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KEY69154.1 - 0.2 11.0 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DASH_Duo1 PF08651.5 KEY69156.1 - 7.3e-31 105.5 0.5 1.1e-30 105.0 0.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 U79_P34 PF03064.11 KEY69156.1 - 0.0058 16.1 2.3 0.0074 15.8 1.6 1.1 1 0 0 1 1 1 1 HSV U79 / HCMV P34 PVL_ORF50 PF07768.6 KEY69156.1 - 0.069 13.1 2.3 0.12 12.4 1.6 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family DinB PF05163.7 KEY69156.1 - 0.11 12.1 2.0 0.18 11.5 1.4 1.4 1 0 0 1 1 1 0 DinB family RNase_H2-Ydr279 PF09468.5 KEY69157.1 - 3.2e-85 286.0 0.1 4.2e-85 285.5 0.1 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) zf-primase PF09329.6 KEY69158.1 - 3e-17 61.9 1.0 5.4e-17 61.1 0.7 1.4 1 0 0 1 1 1 1 Primase zinc finger Tyrosinase PF00264.15 KEY69159.1 - 5.5e-51 173.8 1.9 6.4e-51 173.6 0.5 1.6 2 0 0 2 2 2 1 Common central domain of tyrosinase Acetyltransf_7 PF13508.1 KEY69160.1 - 2.8e-09 37.0 0.0 4.3e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEY69160.1 - 1e-07 31.8 0.0 1.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KEY69160.1 - 6.8e-06 25.9 0.1 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEY69160.1 - 1.2e-05 25.3 0.1 3.5e-05 23.9 0.0 1.7 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEY69160.1 - 2.4e-05 24.0 0.0 6.1e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KEY69160.1 - 0.0033 17.2 0.0 0.009 15.8 0.0 1.8 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 KEY69160.1 - 0.073 12.9 0.1 0.11 12.4 0.1 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Fungal_trans PF04082.13 KEY69161.1 - 1.9e-23 82.6 0.0 3.1e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY69161.1 - 0.0052 16.6 8.3 0.0095 15.8 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spermine_synth PF01564.12 KEY69162.1 - 2e-07 30.1 0.0 3.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_23 PF13489.1 KEY69162.1 - 0.0051 16.5 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY69162.1 - 0.0056 17.2 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.6 KEY69162.1 - 0.042 13.5 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Pyridox_ox_2 PF12900.2 KEY69163.1 - 1.4e-40 138.3 0.0 1.8e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ABC_tran PF00005.22 KEY69166.1 - 1.8e-46 157.8 0.4 1.6e-21 77.0 0.0 3.5 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 KEY69166.1 - 8.6e-21 73.5 8.0 8.6e-21 73.5 5.6 3.8 4 0 0 4 4 4 1 ABC transporter AAA_21 PF13304.1 KEY69166.1 - 8e-17 62.1 1.5 3.8e-05 23.7 0.0 4.7 4 1 1 5 5 5 3 AAA domain SMC_N PF02463.14 KEY69166.1 - 6.6e-11 41.8 2.8 0.0014 17.8 0.0 4.7 5 0 0 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KEY69166.1 - 9.9e-10 39.2 0.3 0.0021 18.8 0.0 3.4 4 0 0 4 4 2 2 AAA domain MMR_HSR1 PF01926.18 KEY69166.1 - 4e-07 29.9 0.0 0.0051 16.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KEY69166.1 - 1.3e-06 27.6 0.0 0.021 14.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KEY69166.1 - 1.4e-06 27.7 0.1 0.013 15.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 KEY69166.1 - 1.5e-06 28.5 0.3 0.09 13.0 0.0 3.4 4 0 0 4 4 2 2 AAA domain AAA_15 PF13175.1 KEY69166.1 - 2.1e-06 27.0 3.1 0.68 8.9 0.0 4.2 4 2 0 4 4 4 3 AAA ATPase domain MobB PF03205.9 KEY69166.1 - 6.7e-06 25.8 0.4 0.094 12.4 0.3 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KEY69166.1 - 9.7e-06 25.5 0.0 0.095 12.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEY69166.1 - 1.2e-05 25.3 0.9 0.03 14.3 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KEY69166.1 - 2.4e-05 24.5 0.0 0.58 10.3 0.1 3.3 3 1 0 3 3 2 2 AAA domain Miro PF08477.8 KEY69166.1 - 4.7e-05 23.8 0.0 0.14 12.6 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 KEY69166.1 - 0.00014 22.0 0.0 0.33 11.1 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 KEY69166.1 - 0.00022 20.1 0.7 0.33 9.6 0.0 2.5 2 0 0 2 2 2 2 ArgK protein AAA_23 PF13476.1 KEY69166.1 - 0.00026 21.3 15.5 0.036 14.4 0.0 4.4 5 0 0 5 5 4 2 AAA domain SbcCD_C PF13558.1 KEY69166.1 - 0.00028 20.7 0.9 0.54 10.2 0.2 3.9 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 KEY69166.1 - 0.00044 20.2 3.5 0.11 12.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.1 KEY69166.1 - 0.00048 20.0 0.0 1.5 8.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KEY69166.1 - 0.0006 19.3 0.2 1.4 8.2 0.0 3.8 4 0 0 4 4 4 1 AAA-like domain NACHT PF05729.7 KEY69166.1 - 0.00096 18.8 0.2 1.5 8.4 0.0 2.7 2 0 0 2 2 2 2 NACHT domain Dynamin_N PF00350.18 KEY69166.1 - 0.0015 18.3 7.9 1.5 8.6 0.1 4.5 5 0 0 5 5 5 2 Dynamin family AAA_25 PF13481.1 KEY69166.1 - 0.0023 17.3 0.2 2.3 7.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain ATP-synt_ab PF00006.20 KEY69166.1 - 0.0025 17.3 0.0 0.31 10.5 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 KEY69166.1 - 0.0026 17.4 0.2 0.48 10.1 0.1 2.6 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.17 KEY69166.1 - 0.004 17.3 0.0 2.5 8.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase cobW PF02492.14 KEY69166.1 - 0.011 15.2 1.5 1.7 8.0 0.7 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 KEY69166.1 - 0.016 14.6 0.0 1.2 8.4 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain T2SE PF00437.15 KEY69166.1 - 0.02 13.7 0.0 0.2 10.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_5 PF07728.9 KEY69166.1 - 0.02 14.6 0.8 6.3 6.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 KEY69166.1 - 0.036 12.9 0.1 7 5.4 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.4 KEY69166.1 - 0.096 12.1 0.1 14 5.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 KEY69166.1 - 0.24 10.8 5.1 10 5.4 0.0 3.5 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 KEY69166.1 - 0.31 10.5 2.0 16 4.9 0.0 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Thymidylate_kin PF02223.12 KEY69166.1 - 1.2 8.5 5.7 1.9 7.8 0.0 3.6 4 0 0 4 4 3 0 Thymidylate kinase DUF3824 PF12868.2 KEY69166.1 - 7.5 7.4 6.4 0.72 10.7 0.3 2.2 2 0 0 2 2 1 0 Domain of unknwon function (DUF3824) Tubulin PF00091.20 KEY69167.1 - 1.8e-70 237.1 0.0 3.3e-70 236.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KEY69167.1 - 2.5e-49 166.5 0.1 3.9e-49 165.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KEY69167.1 - 9.1e-06 25.7 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KEY69167.1 - 0.0046 16.4 0.0 0.0075 15.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Ribosomal_L6 PF00347.18 KEY69168.1 - 6.8e-22 77.7 0.1 8.4e-11 42.2 0.0 3.3 3 1 0 3 3 3 2 Ribosomal protein L6 Inositol_P PF00459.20 KEY69169.1 - 2.7e-53 181.0 2.4 5.1e-53 180.1 1.7 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family Complex1_LYR_2 PF13233.1 KEY69170.1 - 1.3e-15 57.7 0.0 2.2e-15 57.0 0.0 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KEY69170.1 - 0.031 14.0 0.8 0.045 13.5 0.5 1.4 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Aha1_N PF09229.6 KEY69172.1 - 1.8e-38 131.4 0.3 2.7e-38 130.8 0.2 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KEY69172.1 - 8.5e-17 61.4 1.7 1.2e-16 60.8 0.2 1.9 2 1 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein zf-DHHC PF01529.15 KEY69173.1 - 5e-32 110.6 3.5 5e-32 110.6 2.4 1.9 2 1 0 2 2 2 1 DHHC palmitoyltransferase PRRSV_Env PF02340.10 KEY69174.1 - 0.039 13.1 0.6 0.098 11.8 0.0 1.7 1 1 1 2 2 2 0 PRRSV putative envelope protein Rap1_C PF11626.3 KEY69175.1 - 4e-22 77.8 0.0 7.9e-22 76.9 0.0 1.5 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 KEY69175.1 - 2e-16 59.5 1.6 3e-16 58.9 0.1 2.1 2 0 0 2 2 2 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 KEY69175.1 - 8.2e-06 26.3 0.0 2.6e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 Rap1, DNA-binding ARID PF01388.16 KEY69175.1 - 1.5e-05 24.7 0.0 6.6e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 ARID/BRIGHT DNA binding domain Tht1 PF04163.7 KEY69176.1 - 0.00013 20.5 3.9 0.00032 19.2 2.7 1.6 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein MbeD_MobD PF04899.7 KEY69176.1 - 0.003 17.4 1.9 0.54 10.1 0.2 3.3 2 1 0 2 2 2 1 MbeD/MobD like AKAP2_C PF15304.1 KEY69176.1 - 0.012 15.2 1.9 0.019 14.5 0.7 1.8 2 0 0 2 2 2 0 A-kinase anchor protein 2 C-terminus DUF3387 PF11867.3 KEY69176.1 - 0.016 14.1 5.9 0.033 13.1 4.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3387) Abi_C PF14355.1 KEY69176.1 - 0.082 12.8 0.9 1.9 8.4 0.0 3.1 3 0 0 3 3 3 0 Abortive infection C-terminus LIF_OSM PF01291.12 KEY69176.1 - 0.2 11.5 8.5 0.85 9.5 0.1 3.2 1 1 1 3 3 3 0 LIF / OSM family SseC PF04888.7 KEY69176.1 - 0.21 10.9 14.8 0.32 10.2 9.8 1.6 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family CorA PF01544.13 KEY69176.1 - 0.57 9.1 16.9 0.15 11.0 4.3 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Sec34 PF04136.10 KEY69176.1 - 0.65 9.6 5.2 0.65 9.6 1.8 2.2 2 0 0 2 2 2 0 Sec34-like family Snapin_Pallidin PF14712.1 KEY69176.1 - 1.1 9.6 10.8 0.1 12.9 1.8 3.2 3 1 1 4 4 4 0 Snapin/Pallidin PhageMin_Tail PF10145.4 KEY69176.1 - 1.4 8.4 13.3 3.4 7.2 8.7 2.0 1 1 0 1 1 1 0 Phage-related minor tail protein Prominin PF05478.6 KEY69176.1 - 4.3 4.7 11.8 0.45 7.9 3.6 2.0 1 1 1 2 2 2 0 Prominin Peptidase_C6 PF00851.13 KEY69176.1 - 5.1 5.6 7.9 1.5 7.3 2.8 1.9 1 1 1 2 2 2 0 Helper component proteinase T2SF PF00482.18 KEY69176.1 - 7.1 6.5 10.1 13 5.6 1.7 3.3 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F HLH PF00010.21 KEY69177.1 - 3.5e-17 61.8 1.4 1.1e-16 60.2 0.0 2.3 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain DUF2353 PF09789.4 KEY69177.1 - 0.026 13.7 1.3 0.037 13.2 0.9 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) SLX9 PF15341.1 KEY69177.1 - 0.049 14.0 5.5 0.12 12.8 3.8 1.6 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Prenyltrans PF00432.16 KEY69178.1 - 1.9e-34 116.8 34.3 3.6e-08 32.8 0.2 6.3 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KEY69178.1 - 2.9e-21 75.9 0.0 1.3e-13 51.2 0.0 4.1 1 1 4 5 5 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 KEY69178.1 - 1e-05 25.4 0.0 8.2e-05 22.5 0.0 2.4 3 0 0 3 3 3 1 Prenyltransferase-like Peptidase_S8 PF00082.17 KEY69180.1 - 3.7e-47 160.8 14.4 5.7e-47 160.2 10.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KEY69180.1 - 1.7e-11 44.5 0.2 3.1e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 TatD_DNase PF01026.16 KEY69181.1 - 1.5e-41 142.2 0.0 2e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase NatB_MDM20 PF09797.4 KEY69183.1 - 2.4e-26 92.3 0.0 6e-26 91.0 0.0 1.6 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit HisKA PF00512.20 KEY69183.1 - 0.021 14.8 2.2 4.6 7.3 0.1 3.6 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain DUF1903 PF08991.5 KEY69184.1 - 0.039 14.0 0.9 0.039 14.0 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1903) DUF4646 PF15496.1 KEY69187.1 - 0.019 15.0 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) Pro_dh PF01619.13 KEY69188.1 - 7.5e-39 133.5 0.0 1.2e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase NRPS PF08415.5 KEY69188.1 - 0.028 14.1 0.1 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 Nonribosomal peptide synthase AP_endonuc_2 PF01261.19 KEY69188.1 - 0.04 13.1 0.1 0.14 11.4 0.0 1.8 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel GHL6 PF14871.1 KEY69188.1 - 0.049 13.6 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 ADH_zinc_N PF00107.21 KEY69188.1 - 0.08 12.4 0.1 12 5.3 0.0 2.5 1 1 0 2 2 2 0 Zinc-binding dehydrogenase Cellulase PF00150.13 KEY69188.1 - 0.087 12.0 0.0 0.73 8.9 0.0 2.0 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) HAD_2 PF13419.1 KEY69188.1 - 0.11 12.6 0.0 0.87 9.7 0.0 2.3 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Ribosomal_S30AE PF02482.14 KEY69188.1 - 0.13 12.7 0.1 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein DUF871 PF05913.6 KEY69188.1 - 0.15 10.8 0.0 0.49 9.1 0.0 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF871) Oxidored_FMN PF00724.15 KEY69189.1 - 1.4e-91 307.0 0.0 1.7e-91 306.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PNP_UDP_1 PF01048.15 KEY69190.1 - 6.6e-17 61.2 0.0 1.2e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Pkinase PF00069.20 KEY69191.1 - 0.00028 20.1 0.0 0.00046 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain zf-C2H2 PF00096.21 KEY69191.1 - 0.04 14.2 0.7 0.22 11.9 0.0 2.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY69191.1 - 0.18 12.2 0.0 0.18 12.2 0.0 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger adh_short PF00106.20 KEY69192.1 - 1.8e-12 47.5 0.1 4.1e-11 43.0 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY69192.1 - 3.6e-06 26.7 0.0 4.8e-05 23.0 0.0 2.2 1 1 0 2 2 2 1 KR domain Epimerase PF01370.16 KEY69192.1 - 0.0013 18.1 0.0 0.0026 17.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.13 KEY69193.1 - 1.3e-26 93.0 0.3 2.2e-26 92.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY69193.1 - 5.6e-07 29.3 9.9 1e-06 28.4 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KEY69194.1 - 4.5e-08 33.1 0.0 6.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY69194.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 KR domain adh_short_C2 PF13561.1 KEY69194.1 - 0.15 11.7 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Asparaginase_2 PF01112.13 KEY69194.1 - 0.16 10.7 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Asparaginase Helicase_C_3 PF13625.1 KEY69196.1 - 2.2e-23 82.3 0.0 4.9e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEY69196.1 - 2.8e-13 50.1 0.0 7.6e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KEY69196.1 - 5.1e-11 42.2 0.0 1.4e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KEY69196.1 - 2.1e-10 39.8 0.0 3.4e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain p450 PF00067.17 KEY69197.1 - 4.9e-86 289.0 0.0 5.7e-86 288.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SPDY PF03771.11 KEY69198.1 - 0.024 14.0 0.1 0.033 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF317) DUF2232 PF09991.4 KEY69198.1 - 0.66 8.9 3.4 0.73 8.7 2.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF4001 PF13165.1 KEY69198.1 - 5.8 6.6 9.0 3.4 7.4 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4001) DUF89 PF01937.14 KEY69200.1 - 1e-118 396.2 0.0 1.1e-118 396.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Pkinase PF00069.20 KEY69201.1 - 1.7e-14 53.6 0.0 3.7e-14 52.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY69201.1 - 1e-06 28.0 0.0 1.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PRO8NT PF08082.6 KEY69203.1 - 0.068 12.8 4.3 4.5 6.9 0.2 2.9 2 1 1 3 3 3 0 PRO8NT (NUC069), PrP8 N-terminal domain SecIII_SopE_N PF05364.9 KEY69204.1 - 0.17 11.7 1.3 0.32 10.8 0.9 1.4 1 0 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus Aminotran_1_2 PF00155.16 KEY69205.1 - 2.2e-37 128.8 0.0 2.6e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KEY69205.1 - 9.8e-06 24.0 0.0 1.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 KEY69205.1 - 4.8e-05 22.0 0.5 0.00058 18.5 0.4 2.0 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Acyl_transf_1 PF00698.16 KEY69206.1 - 1.8e-68 231.2 0.0 3.4e-68 230.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 KEY69206.1 - 2.9e-65 220.2 0.0 7.3e-65 218.9 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KEY69206.1 - 2e-59 200.3 0.1 1.3e-58 197.6 0.1 2.5 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 KEY69206.1 - 2.4e-58 197.6 1.7 4.2e-58 196.8 1.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KEY69206.1 - 6.7e-44 149.7 0.1 6.7e-44 149.7 0.0 2.7 2 0 0 2 2 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KEY69206.1 - 1.9e-29 101.9 0.6 1.5e-28 99.0 0.1 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KEY69206.1 - 2.3e-17 62.7 0.0 7.7e-17 61.0 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KEY69206.1 - 2.6e-11 43.4 0.0 6.8e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY69206.1 - 1e-08 34.9 0.0 2.8e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY69206.1 - 1.8e-08 34.7 0.0 4.8e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 KEY69206.1 - 7.6e-08 32.0 0.0 2.6e-07 30.3 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KEY69206.1 - 4.2e-07 30.1 0.1 1.2e-06 28.6 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.1 KEY69206.1 - 4.3e-07 30.8 0.0 3.4e-06 27.9 0.0 2.7 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KEY69206.1 - 1.7e-05 25.3 0.0 5.3e-05 23.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY69206.1 - 6.9e-05 23.2 0.0 0.00029 21.2 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Thiolase_N PF00108.18 KEY69206.1 - 0.00089 18.3 1.2 0.0015 17.5 0.3 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 KEY69206.1 - 0.0039 16.6 0.0 0.11 11.9 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase NmrA PF05368.8 KEY69206.1 - 0.018 14.2 0.0 0.046 12.9 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family NodS PF05401.6 KEY69206.1 - 0.049 13.0 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF4084 PF13321.1 KEY69206.1 - 0.2 10.8 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4084) MFS_1 PF07690.11 KEY69207.1 - 7.2e-23 80.8 61.4 1.4e-21 76.6 42.6 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily HET PF06985.6 KEY69208.1 - 2.1e-33 115.4 0.1 3.3e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.18 KEY69209.1 - 3.6e-21 75.0 4.2 3.6e-21 75.0 2.9 1.9 2 0 0 2 2 2 1 FAD binding domain Glyco_hydro_7 PF00840.15 KEY69210.1 - 3.2e-176 585.9 11.1 4.5e-176 585.4 7.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Prenyltrans PF00432.16 KEY69211.1 - 2.2e-35 119.9 11.7 3.3e-08 32.9 0.1 5.6 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KEY69211.1 - 5.8e-20 71.7 1.6 1.1e-09 38.6 0.0 4.6 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KEY69211.1 - 3.1e-07 30.3 2.2 4e-05 23.5 0.0 3.5 2 1 1 3 3 3 1 Prenyltransferase-like Ilm1 PF10311.4 KEY69212.1 - 8.6e-54 181.4 0.4 9.9e-54 181.2 0.3 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 SecD_SecF PF02355.11 KEY69212.1 - 0.12 11.5 0.9 0.36 9.9 0.1 2.1 3 0 0 3 3 3 0 Protein export membrane protein DUF4345 PF14248.1 KEY69212.1 - 0.44 9.9 6.0 0.72 9.3 0.2 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF4345) Pkinase PF00069.20 KEY69213.1 - 3.3e-67 226.3 0.0 4.5e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY69213.1 - 3.7e-40 137.6 0.0 5.3e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY69213.1 - 1.7e-09 37.0 0.0 6.9e-09 35.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KEY69213.1 - 0.0017 17.4 0.0 0.005 15.9 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEY69213.1 - 0.08 12.6 0.1 0.08 12.6 0.1 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEY69213.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 SNF2_N PF00176.18 KEY69214.1 - 3.7e-76 255.7 0.5 5.9e-76 255.1 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEY69214.1 - 5.6e-15 54.9 0.0 1.8e-14 53.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEY69214.1 - 5.4e-08 32.8 0.0 1.2e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KEY69214.1 - 0.00011 21.7 0.0 0.00022 20.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 KEY69214.1 - 0.00024 20.0 0.2 0.23 10.2 0.0 2.4 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 HSA PF07529.8 KEY69214.1 - 0.00055 19.6 3.3 0.00055 19.6 2.3 2.6 3 0 0 3 3 3 1 HSA DEAD_2 PF06733.10 KEY69214.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 NDUF_B8 PF05821.6 KEY69215.1 - 4e-06 26.5 0.1 5.1e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) TRAPPC10 PF12584.3 KEY69217.1 - 2.2e-23 82.4 0.0 3.7e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 KEY69217.1 - 0.0002 20.9 0.3 0.00034 20.1 0.2 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 IF-2B PF01008.12 KEY69218.1 - 1.3e-75 253.9 1.0 1.5e-75 253.7 0.7 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Peptidase_M20 PF01546.23 KEY69219.1 - 1.1e-20 73.9 4.3 1.9e-20 73.2 3.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KEY69219.1 - 4.5e-16 58.5 0.0 8.1e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KEY69219.1 - 0.0038 16.9 0.0 0.0065 16.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.9 KEY69219.1 - 0.02 13.7 0.2 0.091 11.5 0.1 1.9 1 1 1 2 2 2 0 M42 glutamyl aminopeptidase ACP_syn_III_C PF08541.5 KEY69219.1 - 0.089 12.8 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF2205 PF10224.4 KEY69220.1 - 3.8e-31 106.4 0.3 5.7e-31 105.9 0.2 1.3 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) AAA_32 PF13654.1 KEY69220.1 - 0.064 11.9 0.0 0.064 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain TACC PF05010.9 KEY69220.1 - 0.075 12.7 0.9 0.097 12.4 0.2 1.4 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Peptidase_M28 PF04389.12 KEY69221.1 - 3e-33 115.0 0.0 4.3e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KEY69221.1 - 1.5e-15 56.7 0.3 5e-15 55.0 0.1 2.0 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 KEY69221.1 - 7.6e-05 22.3 0.1 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 KEY69221.1 - 0.14 10.9 0.0 0.49 9.1 0.0 1.8 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Glyco_hydro_43 PF04616.9 KEY69224.1 - 4.2e-38 131.0 0.4 6e-38 130.5 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1305 PF06996.6 KEY69225.1 - 0.05 12.6 0.0 0.078 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1305) peroxidase PF00141.18 KEY69226.1 - 4.3e-32 111.4 0.1 6.1e-32 110.9 0.1 1.2 1 0 0 1 1 1 1 Peroxidase p450 PF00067.17 KEY69227.1 - 3.3e-69 233.6 0.0 4e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SDH_alpha PF03313.10 KEY69228.1 - 1.5e-87 293.2 0.2 2.3e-87 292.6 0.2 1.3 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 KEY69228.1 - 1.8e-53 180.8 0.0 3.5e-53 179.8 0.0 1.5 1 0 0 1 1 1 1 Serine dehydratase beta chain Glyco_hydro_6 PF01341.12 KEY69229.1 - 7.8e-86 288.1 0.0 9.2e-86 287.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Peptidase_M28 PF04389.12 KEY69230.1 - 6.8e-33 113.8 0.0 1.2e-32 113.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KEY69230.1 - 4.9e-09 35.8 0.0 1.2e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 KEY69230.1 - 4.7e-06 26.2 0.0 7.3e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 adh_short PF00106.20 KEY69231.1 - 1e-24 87.3 0.5 1.5e-24 86.7 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY69231.1 - 9e-20 71.4 0.3 1.1e-19 71.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.21 KEY69231.1 - 3.2e-06 26.7 0.2 1.1e-05 24.9 0.1 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase KR PF08659.5 KEY69231.1 - 6.3e-06 25.9 0.9 1.4e-05 24.8 0.2 1.7 1 1 1 2 2 2 1 KR domain DUF1776 PF08643.5 KEY69231.1 - 0.0014 17.7 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KEY69231.1 - 0.0026 17.8 0.2 0.0047 16.9 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KEY69231.1 - 0.069 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Eno-Rase_NADH_b PF12242.3 KEY69231.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ApbA PF02558.11 KEY69231.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 KEY69231.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2OG-FeII_Oxy_3 PF13640.1 KEY69232.1 - 1.6e-10 41.4 0.0 3.2e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KEY69232.1 - 1.5e-05 24.5 0.0 3.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APH PF01636.18 KEY69233.1 - 9.4e-13 48.4 0.0 1.7e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEY69233.1 - 0.033 13.7 0.0 0.068 12.7 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 KEY69233.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Pyr_redox_3 PF13738.1 KEY69234.1 - 1.8e-19 70.6 0.0 5.2e-19 69.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEY69234.1 - 9e-10 38.7 0.0 4.6e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY69234.1 - 4.1e-09 36.3 0.1 1.3e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 KEY69234.1 - 4.4e-08 31.7 0.1 1.8e-07 29.7 0.0 1.9 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like DAO PF01266.19 KEY69234.1 - 4e-06 25.9 0.0 1.3e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEY69234.1 - 6.9e-05 21.8 0.3 0.00011 21.1 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KEY69234.1 - 7.7e-05 21.7 0.1 0.00011 21.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 KEY69234.1 - 8.9e-05 21.7 1.3 0.18 10.8 0.7 2.3 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 KEY69234.1 - 0.00076 18.6 0.2 0.0013 17.8 0.2 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 KEY69234.1 - 0.0036 16.2 0.4 0.17 10.7 0.4 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.1 KEY69234.1 - 0.0038 16.2 0.3 0.036 12.9 0.1 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KEY69234.1 - 0.021 13.3 1.2 0.033 12.6 0.8 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 KEY69234.1 - 0.091 12.5 0.4 0.56 9.9 0.1 2.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KEY69234.1 - 4.8 6.1 8.7 1.3 7.9 3.1 2.1 1 1 2 3 3 3 0 FAD dependent oxidoreductase DAO PF01266.19 KEY69235.1 - 5.1e-50 170.3 0.5 6.5e-50 170.0 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KEY69235.1 - 0.00012 21.9 2.2 0.0085 15.8 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 KEY69235.1 - 0.037 12.9 0.0 0.83 8.5 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF4147 PF13660.1 KEY69235.1 - 0.098 11.7 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Aldedh PF00171.17 KEY69236.1 - 1.3e-139 465.5 0.1 8.6e-116 386.9 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DAO PF01266.19 KEY69237.1 - 1e-08 34.5 0.0 7.7e-06 25.0 0.0 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEY69237.1 - 0.098 12.5 0.0 0.16 11.8 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY69237.1 - 0.11 12.5 0.1 0.37 10.8 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KEY69237.1 - 0.15 10.5 0.2 0.22 9.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Aldedh PF00171.17 KEY69238.1 - 4.1e-161 536.4 0.0 5.5e-161 535.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.14 KEY69239.1 - 8.5e-46 156.4 0.0 1.2e-45 155.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY69239.1 - 5.4e-41 140.2 0.0 9.1e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KEY69239.1 - 1.9e-06 27.0 0.0 7.8e-05 21.7 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEY69239.1 - 7.3e-05 21.7 0.3 0.24 10.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KEY69239.1 - 7.5e-05 21.8 1.0 9.8e-05 21.4 0.2 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KEY69239.1 - 0.00045 20.1 0.3 0.0011 18.9 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KEY69239.1 - 0.025 13.2 0.0 0.035 12.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 KEY69239.1 - 0.03 14.1 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 KEY69239.1 - 0.067 11.4 0.0 0.095 10.9 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor Thi4 PF01946.12 KEY69239.1 - 0.097 11.7 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 KEY69239.1 - 0.1 12.3 0.1 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding p450 PF00067.17 KEY69240.1 - 1e-45 156.1 0.0 1.4e-45 155.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.8 KEY69241.1 - 2.3e-34 118.6 0.0 2.9e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY69241.1 - 6.7e-11 42.5 0.0 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 KEY69241.1 - 0.00012 21.9 0.0 0.00025 21.0 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 KEY69241.1 - 0.00025 19.8 0.0 0.00034 19.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KEY69241.1 - 0.0013 18.6 0.1 0.0082 16.0 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 KEY69241.1 - 0.0079 15.6 0.0 0.016 14.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KEY69241.1 - 0.017 15.4 0.0 0.032 14.5 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.3 KEY69242.1 - 3.9e-20 71.8 0.4 1.1e-11 43.9 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY69242.1 - 0.0026 17.6 1.0 0.0026 17.6 0.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.19 KEY69243.1 - 7.8e-10 38.1 0.0 8e-06 24.9 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Lipoprotein_X PF03305.8 KEY69245.1 - 0.24 10.7 0.9 0.4 10.0 0.6 1.2 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein Ammonium_transp PF00909.16 KEY69247.1 - 4.4e-99 331.6 25.0 5.4e-99 331.3 17.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family BLOC1_2 PF10046.4 KEY69248.1 - 0.18 11.9 0.0 0.44 10.7 0.0 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sugar_tr PF00083.19 KEY69249.1 - 6e-71 239.3 22.6 7.2e-71 239.0 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY69249.1 - 1.7e-25 89.4 27.8 3.2e-22 78.7 14.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3445 PF11927.3 KEY69250.1 - 9e-75 251.2 0.0 1.2e-74 250.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) PBP PF01161.15 KEY69250.1 - 5.3e-12 45.8 0.0 3.2e-11 43.2 0.0 2.3 2 1 0 2 2 2 1 Phosphatidylethanolamine-binding protein zf-C2H2_4 PF13894.1 KEY69251.1 - 0.24 11.8 3.0 3.1 8.3 0.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Glyco_hydro_61 PF03443.9 KEY69252.1 - 2.9e-56 190.7 0.0 3.3e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DBINO PF13892.1 KEY69254.1 - 0.056 13.4 1.5 0.081 12.9 1.1 1.1 1 0 0 1 1 1 0 DNA-binding domain Extensin_2 PF04554.8 KEY69254.1 - 0.085 12.7 2.6 0.18 11.7 1.8 1.5 1 0 0 1 1 1 0 Extensin-like region Trypsin PF00089.21 KEY69255.1 - 3.8e-11 43.0 0.0 5.7e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 KEY69255.1 - 1.6e-07 31.3 0.0 2.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain MFS_1 PF07690.11 KEY69256.1 - 8e-24 84.0 54.5 1.9e-12 46.5 21.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tannase PF07519.6 KEY69257.1 - 1.3e-93 314.3 0.1 1.5e-93 314.1 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 KEY69257.1 - 1.1e-07 31.9 0.5 5.6e-07 29.6 0.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY69257.1 - 0.02 14.4 0.6 0.038 13.5 0.4 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold RNA_pol_A_CTD PF03118.10 KEY69257.1 - 0.26 10.7 0.1 10 5.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain Glyco_hydro_61 PF03443.9 KEY69258.1 - 4.4e-56 190.1 0.0 5.5e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 AA_permease PF00324.16 KEY69259.1 - 4.5e-93 312.1 41.4 5.6e-93 311.8 28.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEY69259.1 - 4.7e-29 101.1 46.0 5.7e-29 100.9 31.9 1.1 1 0 0 1 1 1 1 Amino acid permease PI-PLC-X PF00388.14 KEY69260.1 - 2.3e-39 134.0 0.0 3.4e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KEY69260.1 - 9.3e-32 109.4 0.0 1.6e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain MF_alpha PF04648.7 KEY69261.1 - 6e-06 26.1 1.5 36 4.8 0.0 6.1 6 0 0 6 6 6 1 Yeast mating factor alpha hormone Omega-toxin PF06357.6 KEY69261.1 - 1.5 8.4 17.9 12 5.6 0.1 5.8 6 0 0 6 6 6 0 Omega-atracotoxin DUF3873 PF12989.2 KEY69262.1 - 0.058 13.5 0.4 0.13 12.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) Resistin PF06954.6 KEY69262.1 - 0.19 12.0 0.3 0.19 12.0 0.2 2.5 2 0 0 2 2 2 0 Resistin Phytase PF02333.10 KEY69263.1 - 3.1e-63 213.7 0.1 6.1e-63 212.8 0.0 1.4 1 0 0 1 1 1 1 Phytase EGF_2 PF07974.8 KEY69263.1 - 0.00014 21.9 34.2 0.017 15.2 8.8 2.6 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 KEY69263.1 - 3.8 7.7 14.4 1.6 8.9 2.4 2.9 2 0 0 2 2 2 0 Human growth factor-like EGF Amidoligase_2 PF12224.3 KEY69264.1 - 1.8e-10 40.8 0.0 6.9e-09 35.6 0.0 2.5 1 1 0 1 1 1 1 Putative amidoligase enzyme WD40 PF00400.27 KEY69265.1 - 7.4e-83 269.7 26.9 5.5e-16 57.7 1.1 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 KEY69265.1 - 5.8e-06 26.1 0.5 0.016 14.8 0.0 3.4 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KEY69265.1 - 0.00013 21.5 0.1 0.69 9.6 0.0 4.0 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat NLE PF08154.7 KEY69265.1 - 0.00016 21.5 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 KEY69265.1 - 0.00032 18.9 3.8 0.086 10.9 0.0 4.0 3 2 0 4 4 4 2 Nucleoporin Nup120/160 Proteasome_A_N PF10584.4 KEY69265.1 - 0.015 14.5 0.2 5.2 6.4 0.0 4.0 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Glyco_transf_20 PF00982.16 KEY69266.1 - 6e-166 552.6 0.1 8.1e-166 552.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KEY69266.1 - 1.2e-48 165.1 0.0 2.1e-48 164.2 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 KEY69266.1 - 2.1e-05 24.2 0.0 0.024 14.2 0.0 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Glyco_transf_5 PF08323.6 KEY69266.1 - 0.034 13.6 0.4 0.082 12.3 0.3 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain Aminotran_4 PF01063.14 KEY69267.1 - 5.9e-21 74.9 0.0 8e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV FAR1 PF03101.10 KEY69268.1 - 0.0004 20.8 0.2 0.0004 20.8 0.2 2.4 2 1 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.6 KEY69268.1 - 0.073 13.2 0.6 0.073 13.2 0.4 2.9 2 2 0 2 2 2 0 Transcription factor AFT Peptidase_U57 PF05582.7 KEY69268.1 - 0.15 10.9 5.4 0.21 10.5 3.7 1.3 1 0 0 1 1 1 0 YabG peptidase U57 DUF3353 PF11833.3 KEY69268.1 - 0.98 8.8 7.0 1.5 8.2 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) eIF-3_zeta PF05091.7 KEY69268.1 - 2.9 6.4 13.2 4.1 5.9 9.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ndc1_Nup PF09531.5 KEY69268.1 - 5.8 5.1 5.9 6.6 5.0 4.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MutS_III PF05192.13 KEY69269.1 - 1.2e-33 116.5 3.3 3.7e-32 111.7 2.3 2.2 1 1 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 KEY69269.1 - 9.2e-10 38.5 0.0 1.8e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 KEY69269.1 - 0.00015 21.8 0.1 0.00061 19.8 0.0 2.1 2 0 0 2 2 2 1 MutS domain II Biopterin_H PF00351.16 KEY69269.1 - 0.032 12.9 0.1 0.26 9.9 0.0 2.0 2 0 0 2 2 2 0 Biopterin-dependent aromatic amino acid hydroxylase MutS_V PF00488.16 KEY69270.1 - 3.2e-61 206.7 0.2 3.9e-61 206.4 0.2 1.1 1 0 0 1 1 1 1 MutS domain V Dynamin_N PF00350.18 KEY69271.1 - 2.2e-29 102.4 0.0 5.9e-29 101.0 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KEY69271.1 - 1.3e-07 30.7 0.0 3.3e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 KEY69271.1 - 4.8e-05 23.3 0.0 0.00013 21.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEY69271.1 - 0.0058 17.1 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein DUF605 PF04652.11 KEY69271.1 - 0.059 12.7 11.7 0.088 12.1 8.1 1.2 1 0 0 1 1 1 0 Vta1 like ABC_tran PF00005.22 KEY69271.1 - 0.3 11.3 0.0 0.3 11.3 0.0 2.1 2 1 0 2 2 2 0 ABC transporter Hid1 PF12722.2 KEY69271.1 - 8.3 3.9 8.7 12 3.4 6.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cation_efflux PF01545.16 KEY69272.1 - 1.1e-31 109.9 2.5 1.5e-31 109.5 1.7 1.1 1 0 0 1 1 1 1 Cation efflux family FAD_binding_4 PF01565.18 KEY69274.1 - 2.8e-19 68.9 1.0 5.4e-19 68.0 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY69274.1 - 2e-10 40.3 0.0 4.9e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like EutQ PF06249.7 KEY69275.1 - 7.2e-11 41.8 0.0 8.9e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 KEY69275.1 - 3.7e-09 35.8 0.0 6.8e-09 34.9 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 KEY69275.1 - 0.00066 19.1 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KEY69275.1 - 0.003 17.1 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 Cupin KduI PF04962.7 KEY69275.1 - 0.052 12.6 0.0 0.059 12.4 0.0 1.1 1 0 0 1 1 1 0 KduI/IolB family DUF3445 PF11927.3 KEY69276.1 - 3.8e-78 262.3 0.0 4.8e-78 261.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Fungal_trans_2 PF11951.3 KEY69277.1 - 1.7e-23 82.8 0.6 1.1e-18 67.0 1.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY69277.1 - 4.6e-07 29.6 11.2 7.7e-07 28.9 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Caleosin PF05042.8 KEY69278.1 - 1.8e-47 161.1 0.0 2.2e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.1 KEY69278.1 - 0.0059 16.3 1.4 0.48 10.4 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 KEY69278.1 - 0.016 14.4 0.7 1 8.8 0.0 2.7 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.1 KEY69278.1 - 0.086 12.4 0.2 7.1 6.3 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain pair Thioredoxin_7 PF13899.1 KEY69279.1 - 1.5e-13 50.5 0.0 3.4e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 KEY69279.1 - 5.2e-13 48.2 0.0 1.3e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 KEY69279.1 - 1.2e-09 38.1 0.0 2.1e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.10 KEY69279.1 - 0.0081 15.8 0.1 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 UBA PF00627.26 KEY69279.1 - 0.034 14.0 0.5 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 UBA/TS-N domain Thioredoxin_2 PF13098.1 KEY69279.1 - 0.053 13.7 0.1 0.17 12.0 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain Pol_alpha_B_N PF08418.5 KEY69279.1 - 0.2 11.1 2.7 0.45 10.0 1.9 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Iso_dh PF00180.15 KEY69280.1 - 3.3e-81 272.9 0.0 5.6e-81 272.1 0.0 1.3 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pkinase PF00069.20 KEY69280.1 - 1e-69 234.5 0.0 1.5e-69 234.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY69280.1 - 5.5e-50 169.8 0.0 1e-49 169.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY69280.1 - 0.0099 14.8 0.0 0.053 12.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like MFS_1 PF07690.11 KEY69281.1 - 7.7e-28 97.2 27.3 1.7e-14 53.3 11.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY69281.1 - 0.00011 20.9 14.5 0.00059 18.5 10.0 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 KEY69281.1 - 0.024 12.6 6.6 1.3 6.9 0.0 3.2 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 KEY69281.1 - 1.5 8.6 10.2 0.91 9.3 0.3 3.3 4 0 0 4 4 4 0 MFS_1 like family peroxidase PF00141.18 KEY69282.1 - 3.1e-14 53.0 0.5 2.8e-13 49.8 0.1 2.0 2 0 0 2 2 2 1 Peroxidase PSI_PSAK PF01241.13 KEY69282.1 - 0.023 14.6 0.1 0.049 13.6 0.1 1.5 1 0 0 1 1 1 0 Photosystem I psaG / psaK Zip PF02535.17 KEY69282.1 - 0.072 12.0 1.4 0.12 11.4 1.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter TRAP_alpha PF03896.11 KEY69282.1 - 0.99 8.3 3.5 1.5 7.7 2.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nucleoplasmin PF03066.10 KEY69282.1 - 8.3 5.9 10.2 13 5.2 7.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 KEY69282.1 - 9.6 5.3 6.0 13 4.8 4.2 1.1 1 0 0 1 1 1 0 NOA36 protein DUF1295 PF06966.7 KEY69283.1 - 8.9e-31 106.9 0.0 1.3e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 KEY69283.1 - 0.0067 16.6 0.1 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Adeno_PIX PF03955.9 KEY69283.1 - 0.0072 16.8 1.1 2.5 8.6 0.0 3.4 1 1 2 3 3 3 1 Adenovirus hexon-associated protein (IX) Steroid_dh PF02544.11 KEY69283.1 - 0.029 14.1 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase Aminotran_1_2 PF00155.16 KEY69284.1 - 5.9e-43 147.2 0.0 7e-43 146.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Pep3_Vps18 PF05131.9 KEY69284.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Pep3/Vps18/deep orange family HAD_2 PF13419.1 KEY69285.1 - 1.5e-28 100.1 0.0 1.9e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEY69285.1 - 1.1e-07 31.4 0.0 1.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KEY69285.1 - 2.4e-06 28.1 0.0 5.2e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3226 PF11536.3 KEY69285.1 - 0.0084 15.5 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3226) tRNA-synt_2 PF00152.15 KEY69286.1 - 9.1e-88 294.2 0.2 1.4e-87 293.6 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 KEY69286.1 - 2.4e-07 30.2 0.4 0.00047 19.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 KEY69286.1 - 2.8e-06 27.0 0.0 6.4e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Vg_Tdu PF07545.9 KEY69286.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Vestigial/Tondu family WBS_methylT PF12589.3 KEY69287.1 - 3.3e-17 62.7 2.6 6.4e-17 61.8 1.8 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 KEY69287.1 - 4.7e-11 43.0 0.0 1e-10 41.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY69287.1 - 1.5e-07 31.7 0.0 3.5e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY69287.1 - 4.1e-06 26.4 0.0 7.2e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY69287.1 - 1.7e-05 24.5 0.0 2.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KEY69287.1 - 5.4e-05 22.8 0.0 0.00014 21.4 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 KEY69287.1 - 5.5e-05 23.5 0.0 0.00016 22.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY69287.1 - 8.3e-05 22.6 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY69287.1 - 0.0001 22.8 0.0 0.00026 21.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KEY69287.1 - 0.0024 16.9 0.0 0.081 11.9 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 KEY69287.1 - 0.0068 15.5 0.0 0.026 13.6 0.0 2.0 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Erv26 PF04148.8 KEY69288.1 - 1.4e-84 282.7 1.1 1.7e-84 282.4 0.7 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF3377 PF11857.3 KEY69288.1 - 0.0072 15.9 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) Cytochrom_C_asm PF01578.15 KEY69288.1 - 0.096 12.2 0.2 0.096 12.2 0.1 1.8 1 1 0 2 2 2 0 Cytochrome C assembly protein QueT PF06177.6 KEY69288.1 - 0.12 12.3 4.0 0.075 13.0 1.4 1.6 2 0 0 2 2 2 0 QueT transporter MSA-2c PF12238.3 KEY69289.1 - 0.18 11.4 1.7 0.16 11.6 0.4 1.5 1 1 0 1 1 1 0 Merozoite surface antigen 2c ADH_N PF08240.7 KEY69290.1 - 1e-08 34.9 0.0 6.3e-08 32.3 0.0 2.1 1 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY69290.1 - 8.8e-08 31.7 0.0 1.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY69290.1 - 1.4e-05 26.0 0.0 5.3e-05 24.1 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase DSPc PF00782.15 KEY69290.1 - 0.15 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain ApbA PF02558.11 KEY69291.1 - 1e-23 83.4 0.0 1.3e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KEY69291.1 - 2.1e-19 69.7 0.0 3.7e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ThiF PF00899.16 KEY69291.1 - 0.27 11.0 2.0 0.36 10.6 0.6 1.8 2 0 0 2 2 2 0 ThiF family Oxidored_FMN PF00724.15 KEY69292.1 - 1.6e-89 300.2 0.0 1.9e-89 300.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pkinase PF00069.20 KEY69293.1 - 3.6e-28 98.4 0.0 2.3e-27 95.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY69293.1 - 2.2e-08 33.5 0.1 0.0032 16.5 0.0 3.6 3 1 0 3 3 3 3 Protein tyrosine kinase Glyco_hydro_43 PF04616.9 KEY69295.1 - 2.5e-09 36.6 1.6 5.6e-09 35.4 0.4 1.8 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KEY69295.1 - 0.00038 19.9 0.0 0.00088 18.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain GST_C PF00043.20 KEY69296.1 - 1.2e-10 41.2 0.0 2.3e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KEY69296.1 - 1.6e-10 41.0 0.0 2.7e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEY69296.1 - 2.3e-10 40.2 0.0 5.1e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KEY69296.1 - 3.7e-10 39.8 0.0 1.1e-09 38.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEY69296.1 - 7.3e-06 25.7 0.0 1.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEY69296.1 - 0.00012 22.4 0.0 0.00017 21.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Phospholip_A2_3 PF09056.6 KEY69297.1 - 5.9e-44 148.8 0.3 7.7e-44 148.4 0.2 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 GPS PF01825.16 KEY69297.1 - 0.25 11.5 1.8 0.67 10.1 1.2 1.7 1 1 0 1 1 1 0 Latrophilin/CL-1-like GPS domain Ank PF00023.25 KEY69299.1 - 2.2e-08 33.4 0.0 1.4e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 KEY69299.1 - 9.7e-07 29.0 0.0 2.3e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEY69299.1 - 7.2e-05 22.6 0.0 0.00085 19.3 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 KEY69299.1 - 0.016 15.4 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Amidase PF01425.16 KEY69300.1 - 7e-80 269.0 0.0 1e-79 268.5 0.0 1.2 1 0 0 1 1 1 1 Amidase Ecm29 PF13001.2 KEY69301.1 - 5.5e-114 381.4 0.0 2.5e-113 379.2 0.0 2.1 2 0 0 2 2 2 1 Proteasome stabiliser HEAT PF02985.17 KEY69301.1 - 0.0026 17.7 11.4 7.6 6.9 0.0 7.4 7 0 0 7 7 7 1 HEAT repeat Sec7_N PF12783.2 KEY69301.1 - 0.15 11.4 0.8 6.8 6.0 0.2 3.0 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_EZ PF13513.1 KEY69301.1 - 0.25 11.9 10.1 13 6.4 0.0 7.1 6 1 1 7 7 7 0 HEAT-like repeat RRM_1 PF00076.17 KEY69302.1 - 9e-46 153.3 0.0 1.5e-16 59.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY69302.1 - 1.6e-25 88.8 0.0 6.1e-10 38.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY69302.1 - 5.3e-22 77.4 0.1 1.3e-08 34.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KEY69302.1 - 1.4e-05 24.9 0.0 0.00015 21.5 0.0 2.4 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 KEY69302.1 - 2.7e-05 23.8 0.1 0.0034 17.1 0.0 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif 4HBT_3 PF13622.1 KEY69303.1 - 2.2e-23 83.3 0.0 5.9e-23 81.9 0.0 1.6 2 0 0 2 2 2 1 Thioesterase-like superfamily DUF4625 PF15418.1 KEY69303.1 - 0.046 13.8 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4625) Cyclase PF04199.8 KEY69305.1 - 3.7e-17 62.5 0.0 5.8e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase adh_short_C2 PF13561.1 KEY69306.1 - 2.6e-33 115.8 0.0 3.1e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEY69306.1 - 3.1e-23 82.5 0.3 4.1e-23 82.1 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY69306.1 - 1e-09 38.2 0.1 1.8e-09 37.5 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY69306.1 - 2.2e-05 23.9 0.1 4.6e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KEY69306.1 - 0.013 15.3 0.1 0.029 14.1 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 KEY69306.1 - 0.026 13.4 0.1 0.032 13.1 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SOR_SNZ PF01680.12 KEY69308.1 - 1.3e-106 354.8 6.9 1.7e-106 354.4 4.8 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 KEY69308.1 - 1.7e-09 37.1 3.4 7.1e-07 28.5 0.0 2.6 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KEY69308.1 - 4.7e-05 22.7 0.4 0.031 13.5 0.0 3.2 3 1 0 3 3 3 1 Histidine biosynthesis protein IGPS PF00218.16 KEY69308.1 - 0.00018 20.6 0.8 0.0011 18.0 0.0 2.4 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase Dus PF01207.12 KEY69308.1 - 0.00026 19.9 0.2 0.29 9.9 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) DUF4398 PF14346.1 KEY69308.1 - 0.0012 18.8 2.1 0.002 18.1 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4398) NanE PF04131.9 KEY69308.1 - 0.0023 16.8 0.8 0.11 11.5 0.0 2.8 2 2 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.12 KEY69308.1 - 0.011 14.8 0.7 0.57 9.2 0.1 2.6 2 1 0 2 2 2 0 Thiamine monophosphate synthase/TENI OMPdecase PF00215.19 KEY69308.1 - 0.018 14.4 0.7 0.026 13.8 0.5 1.5 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family NMO PF03060.10 KEY69308.1 - 2.6 7.0 15.5 0.32 10.0 1.5 3.1 2 2 1 3 3 3 0 Nitronate monooxygenase SNO PF01174.14 KEY69309.1 - 9.5e-53 178.6 0.0 1.3e-50 171.6 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 KEY69309.1 - 1.2e-08 34.6 0.0 6.6e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain DUF4066 PF13278.1 KEY69309.1 - 0.0018 17.5 0.2 0.0034 16.6 0.1 1.4 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KEY69309.1 - 0.0048 16.3 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.12 KEY69309.1 - 0.096 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 Ank_2 PF12796.2 KEY69310.1 - 8.5e-60 199.1 2.5 4.8e-19 68.4 0.4 5.4 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KEY69310.1 - 2.3e-43 143.8 8.4 8.4e-07 28.5 0.0 11.4 11 0 0 11 11 11 10 Ankyrin repeat Ank_3 PF13606.1 KEY69310.1 - 1.5e-35 117.6 0.1 0.00018 21.4 0.0 10.6 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.1 KEY69310.1 - 3.3e-34 116.6 2.9 4.2e-07 30.3 0.0 8.3 4 4 4 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY69310.1 - 2.5e-33 113.3 3.1 2.7e-07 30.5 0.0 7.6 4 2 2 7 7 7 6 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 KEY69310.1 - 0.00012 21.6 0.9 18 4.7 0.0 4.9 4 2 1 5 5 5 1 Shigella flexneri OspC protein Met_asp_mut_E PF06368.6 KEY69310.1 - 0.11 10.6 0.0 0.71 7.9 0.0 2.1 2 0 0 2 2 2 0 Methylaspartate mutase E chain (MutE) DUF3232 PF11554.3 KEY69310.1 - 0.13 12.1 0.1 1.4 8.7 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3232) Chal_sti_synt_N PF00195.14 KEY69311.1 - 6e-29 100.8 0.0 8e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.10 KEY69311.1 - 1.6e-20 73.5 0.0 8.2e-20 71.2 0.0 1.9 2 0 0 2 2 2 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.7 KEY69311.1 - 1.2e-07 31.1 0.0 1.6e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.5 KEY69311.1 - 2.4e-06 27.4 0.0 1.5e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 KEY69311.1 - 6e-05 22.6 0.1 0.00015 21.3 0.1 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HpcH_HpaI PF03328.9 KEY69312.1 - 9.9e-28 96.5 0.0 1.3e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family TTSSLRR PF12468.3 KEY69312.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein SGL PF08450.7 KEY69313.1 - 0.00072 19.0 0.0 0.0024 17.3 0.0 1.8 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Acyl_transf_1 PF00698.16 KEY69314.1 - 1.6e-88 297.1 0.1 2.4e-88 296.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 KEY69314.1 - 4.9e-80 268.6 0.1 9.7e-80 267.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KEY69314.1 - 2e-60 203.5 1.0 1.1e-58 197.8 0.3 2.8 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 KEY69314.1 - 1.6e-49 168.0 1.3 1.5e-48 164.9 0.4 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KEY69314.1 - 3.7e-35 120.3 2.8 3.8e-35 120.3 0.5 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 KEY69314.1 - 6.3e-12 45.2 0.0 1.9e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase PP-binding PF00550.20 KEY69314.1 - 5.2e-11 42.6 0.0 1.7e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KEY69314.1 - 0.00019 20.5 0.1 0.00044 19.3 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain DHDPS PF00701.17 KEY69315.1 - 4.4e-49 166.6 0.0 5.2e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family FlpD PF02662.11 KEY69315.1 - 0.15 11.7 0.6 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit Ank_2 PF12796.2 KEY69316.1 - 1.6e-18 66.8 0.1 5.4e-10 39.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEY69316.1 - 9.5e-13 47.2 0.5 0.00014 21.4 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KEY69316.1 - 8.5e-11 41.0 0.1 0.0028 17.7 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KEY69316.1 - 1.7e-09 37.5 0.3 3.3e-05 23.9 0.1 4.0 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEY69316.1 - 2.1e-09 37.6 0.0 0.00098 19.5 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Glyco_transf_54 PF04666.8 KEY69317.1 - 7.6e-15 54.4 0.0 1.1e-07 30.8 0.0 2.7 3 0 0 3 3 3 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region MscS_TM PF12794.2 KEY69317.1 - 0.035 12.7 0.0 0.059 11.9 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Glyco_transf_90 PF05686.7 KEY69318.1 - 5.6e-14 51.6 0.0 1.7e-08 33.5 0.0 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 90 2H-phosphodiest PF08975.5 KEY69318.1 - 0.095 12.4 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) Glyco_hydro_2_N PF02837.13 KEY69319.1 - 3.5e-29 101.4 0.0 8.2e-29 100.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KEY69319.1 - 3.5e-10 39.2 0.0 2.5e-09 36.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KEY69319.1 - 1.8e-08 34.8 0.1 5.2e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Gmad2 PF10648.4 KEY69319.1 - 0.039 14.1 0.8 0.71 10.0 0.1 2.5 2 0 0 2 2 2 0 Immunoglobulin-like domain of bacterial spore germination ATP-grasp PF02222.17 KEY69320.1 - 3.5e-19 68.8 0.0 6.5e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ctr PF04145.10 KEY69321.1 - 3.1e-39 134.2 2.8 3.6e-39 134.0 2.0 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Oxidored_q3 PF00499.15 KEY69321.1 - 1.1 9.0 9.6 0.76 9.5 2.6 2.1 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Ferric_reduct PF01794.14 KEY69322.1 - 6.9e-20 71.3 9.4 2e-19 69.8 6.5 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KEY69322.1 - 1.5e-18 67.2 0.0 2.1e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KEY69322.1 - 1.3e-07 31.4 0.0 2.7e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KEY69322.1 - 9e-07 29.4 0.0 2.5e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain VWA_3 PF13768.1 KEY69324.1 - 3.4e-28 98.2 0.0 6.3e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 KEY69324.1 - 2.2e-18 66.0 0.0 6e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 KEY69324.1 - 1.9e-13 50.9 0.1 6.8e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.1 KEY69324.1 - 1.1e-10 40.8 0.0 2.8e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 KEY69324.1 - 1.5e-07 31.3 0.0 3.5e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 KEY69324.1 - 0.0031 16.6 0.0 0.0062 15.6 0.0 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein adh_short PF00106.20 KEY69325.1 - 6.5e-32 110.7 0.5 8.5e-32 110.3 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY69325.1 - 8.8e-21 74.7 0.0 1.1e-20 74.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY69325.1 - 4.7e-15 55.6 0.3 7.2e-15 55.1 0.2 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY69325.1 - 0.00032 20.2 0.0 0.00047 19.6 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY69325.1 - 0.00064 19.7 0.3 0.002 18.1 0.1 1.8 2 1 1 3 3 3 1 NADH(P)-binding Glyco_transf_5 PF08323.6 KEY69325.1 - 0.0043 16.5 0.0 0.092 12.2 0.0 2.1 2 0 0 2 2 2 1 Starch synthase catalytic domain 3HCDH_N PF02737.13 KEY69325.1 - 0.17 11.5 0.3 0.3 10.7 0.1 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DHDPS PF00701.17 KEY69326.1 - 3.4e-45 153.8 0.0 4.1e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF442 PF04273.8 KEY69326.1 - 0.085 12.7 0.0 0.43 10.4 0.0 2.0 1 1 1 2 2 2 0 Putative phosphatase (DUF442) ApbA PF02558.11 KEY69327.1 - 3.2e-33 114.3 0.1 4.3e-33 113.9 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KEY69327.1 - 1e-29 103.0 0.0 1.6e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Saccharop_dh PF03435.13 KEY69327.1 - 0.01 14.8 0.1 0.019 13.9 0.0 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NAD_Gly3P_dh_N PF01210.18 KEY69327.1 - 0.017 14.8 0.1 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus eIF-5a PF01287.15 KEY69327.1 - 0.028 14.3 0.0 1.5 8.8 0.0 2.6 2 1 0 2 2 2 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold adh_short PF00106.20 KEY69327.1 - 0.059 13.2 0.3 0.2 11.5 0.0 2.0 2 1 0 2 2 2 0 short chain dehydrogenase ThiF PF00899.16 KEY69327.1 - 0.1 12.4 0.3 0.44 10.3 0.0 2.0 1 1 1 2 2 2 0 ThiF family FMN_dh PF01070.13 KEY69328.1 - 4.2e-99 331.7 0.0 1.4e-98 330.0 0.0 1.7 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KEY69328.1 - 1.3e-20 72.9 0.0 4e-20 71.4 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KEY69328.1 - 1.9e-06 27.0 0.1 2.8e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KEY69328.1 - 0.0029 16.5 2.0 0.0081 15.0 0.9 2.0 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 KEY69328.1 - 0.031 13.3 0.2 2.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.12 KEY69328.1 - 0.11 11.5 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI FAD_binding_4 PF01565.18 KEY69329.1 - 4.4e-20 71.5 2.7 8.1e-20 70.7 1.9 1.5 1 0 0 1 1 1 1 FAD binding domain ATP-grasp_4 PF13535.1 KEY69330.1 - 0.00028 20.6 0.0 0.013 15.2 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KEY69330.1 - 0.0016 18.3 0.0 0.0069 16.2 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain MFS_1 PF07690.11 KEY69331.1 - 2.2e-20 72.6 44.8 2.2e-20 72.6 31.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 KEY69332.1 - 6.5e-10 38.9 0.1 9.8e-10 38.3 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEY69332.1 - 1.2e-06 28.6 0.0 2.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEY69332.1 - 2.4e-06 27.6 0.0 5.2e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KEY69332.1 - 0.00093 19.0 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 KEY69332.1 - 0.00098 18.8 0.1 0.0023 17.6 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KEY69332.1 - 0.002 17.9 0.0 0.0084 15.9 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Glyco_hydro_2_N PF02837.13 KEY69333.1 - 0.004 16.7 0.0 0.018 14.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Carb_anhydrase PF00194.16 KEY69334.1 - 2.4e-13 49.6 0.0 1e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Ank_2 PF12796.2 KEY69336.1 - 1.5e-83 275.1 0.0 8.1e-13 48.5 0.0 8.2 4 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KEY69336.1 - 8e-64 208.4 2.1 5.7e-06 25.8 0.0 16.0 16 0 0 16 16 16 14 Ankyrin repeat Ank_4 PF13637.1 KEY69336.1 - 4.3e-51 170.4 0.7 2.7e-07 30.9 0.0 12.9 6 4 7 14 14 14 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY69336.1 - 1.7e-45 148.4 0.0 0.00013 21.9 0.0 15.2 16 0 0 16 16 16 9 Ankyrin repeat Ank_5 PF13857.1 KEY69336.1 - 1.9e-42 142.3 4.4 2.4e-06 27.5 0.0 11.4 7 4 6 13 13 13 10 Ankyrin repeats (many copies) MOZART1 PF12554.3 KEY69336.1 - 0.18 11.2 1.2 1.3e+02 2.1 0.0 5.0 5 0 0 5 5 5 0 Mitotic-spindle organizing gamma-tubulin ring associated Chordopox_G2 PF05796.7 KEY69337.1 - 0.17 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus protein G2 AMP-binding PF00501.23 KEY69338.1 - 5.1e-96 321.6 0.0 6.2e-96 321.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEY69338.1 - 2.3e-21 76.4 1.3 3.2e-21 76.0 0.2 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HRXXH PF13933.1 KEY69339.1 - 1.3e-101 339.2 0.0 1.9e-101 338.6 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Glyco_tranf_2_3 PF13641.1 KEY69341.1 - 0.11 12.3 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 NACHT PF05729.7 KEY69342.1 - 1.5e-08 34.4 0.0 4.3e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEY69342.1 - 0.00027 20.9 0.1 0.0016 18.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KEY69342.1 - 0.00043 21.0 0.0 0.096 13.5 0.0 3.7 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KEY69342.1 - 0.0017 17.8 1.5 0.13 11.6 0.1 3.2 2 1 1 3 3 3 1 AAA-like domain AAA_22 PF13401.1 KEY69342.1 - 0.0051 16.9 0.1 0.039 14.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain NB-ARC PF00931.17 KEY69342.1 - 0.006 15.4 0.0 0.18 10.6 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.1 KEY69342.1 - 0.0066 16.0 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KEY69342.1 - 0.015 14.7 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain HSBP1 PF06825.7 KEY69342.1 - 0.019 14.5 0.1 12 5.5 0.0 3.7 2 1 0 2 2 2 0 Heat shock factor binding protein 1 ABC_tran PF00005.22 KEY69342.1 - 0.028 14.7 0.0 0.19 11.9 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Arch_ATPase PF01637.13 KEY69342.1 - 0.044 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_23 PF13476.1 KEY69342.1 - 0.046 14.0 0.0 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Ank PF00023.25 KEY69342.1 - 0.07 12.9 0.0 6.7 6.7 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeat HET PF06985.6 KEY69346.1 - 4.4e-25 88.4 0.1 6.5e-25 87.9 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GST_C PF00043.20 KEY69347.1 - 1.1e-14 54.1 0.0 2.1e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KEY69347.1 - 3.4e-11 43.1 0.0 8.7e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KEY69347.1 - 4e-11 42.9 0.0 7.8e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEY69347.1 - 7.8e-10 38.5 0.0 2.4e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KEY69347.1 - 1.2e-08 34.7 0.0 3.1e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KEY69347.1 - 7.6e-08 32.7 0.0 2e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 KEY69347.1 - 0.19 12.1 0.0 0.44 10.9 0.0 1.5 1 0 0 1 1 1 0 MetRS-N binding domain CFEM PF05730.6 KEY69349.1 - 2.3e-14 52.9 14.1 4.1e-14 52.1 9.7 1.4 1 0 0 1 1 1 1 CFEM domain adh_short PF00106.20 KEY69350.1 - 1.4e-05 25.0 0.0 3.1e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 KEY69350.1 - 0.028 14.1 1.7 0.064 13.0 1.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Zn_clus PF00172.13 KEY69351.1 - 2.9e-08 33.5 9.9 5.5e-08 32.5 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3419 PF11899.3 KEY69351.1 - 0.053 12.2 0.1 0.11 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Peptidase_M28 PF04389.12 KEY69352.1 - 6.1e-37 127.0 0.0 9.6e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KEY69352.1 - 1.3e-10 40.8 0.0 4.4e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 KEY69352.1 - 2.5e-05 23.8 0.0 3.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Lipase_3 PF01764.20 KEY69353.1 - 5.4e-32 110.3 0.0 7.8e-32 109.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 KEY69353.1 - 6.8e-06 25.8 0.1 1.2e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Lipase 3 N-terminal region DUF2974 PF11187.3 KEY69353.1 - 0.00016 21.1 0.0 0.0049 16.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 KEY69353.1 - 0.0017 18.2 0.1 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KEY69353.1 - 0.0019 17.5 0.0 0.003 16.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 KEY69353.1 - 0.0032 17.2 0.0 0.0036 17.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KEY69353.1 - 0.014 15.6 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.8 KEY69353.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2048 PF09752.4 KEY69353.1 - 0.035 12.9 0.1 0.086 11.6 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Cutinase PF01083.17 KEY69353.1 - 0.051 13.3 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 Cutinase Abhydrolase_8 PF06259.7 KEY69353.1 - 0.072 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase adh_short PF00106.20 KEY69354.1 - 1.1e-18 67.7 1.4 1.7e-18 67.0 1.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY69354.1 - 2.8e-08 33.8 0.1 4.4e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY69354.1 - 6.1e-08 32.5 0.1 8.9e-08 31.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY69354.1 - 1.1e-06 28.2 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AIRC PF00731.15 KEY69354.1 - 0.019 14.2 0.5 0.049 12.9 0.1 1.9 2 0 0 2 2 2 0 AIR carboxylase Amidase PF01425.16 KEY69355.1 - 2.3e-74 250.8 0.0 2.9e-74 250.5 0.0 1.1 1 0 0 1 1 1 1 Amidase Zn_clus PF00172.13 KEY69355.1 - 0.00043 20.1 11.5 0.0011 18.8 7.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 KEY69356.1 - 9.9e-43 146.2 5.2 1.3e-42 145.7 3.6 1.1 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.13 KEY69357.1 - 0.00039 20.2 11.2 0.00094 19.0 1.0 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEY69357.1 - 0.011 14.3 0.5 0.016 13.7 0.3 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Fungal_trans PF04082.13 KEY69358.1 - 2.8e-10 39.5 0.0 4.5e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY69358.1 - 1.2e-08 34.7 9.1 1.2e-08 34.7 6.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KEY69359.1 - 1.7e-35 122.4 50.5 1.7e-22 79.6 17.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY69359.1 - 1.2e-05 24.1 33.6 0.00042 19.0 10.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter YqzM PF14141.1 KEY69359.1 - 9.1 6.1 10.2 24 4.8 0.4 2.8 2 0 0 2 2 2 0 YqzM-like protein FAD_binding_3 PF01494.14 KEY69360.1 - 3.8e-21 75.5 0.0 2.5e-11 43.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KEY69360.1 - 8e-05 22.5 0.1 0.00019 21.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KEY69360.1 - 0.00011 21.4 0.1 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KEY69360.1 - 0.00035 20.5 0.0 0.0012 18.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KEY69360.1 - 0.0037 16.1 0.0 0.02 13.7 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.19 KEY69360.1 - 0.008 15.1 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEY69360.1 - 0.013 15.8 0.2 0.061 13.7 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CDP-OH_P_transf PF01066.16 KEY69360.1 - 0.068 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase UDPG_MGDP_dh_N PF03721.9 KEY69360.1 - 0.069 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KEY69360.1 - 0.076 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus A1_Propeptide PF07966.7 KEY69360.1 - 0.16 11.7 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 A1 Propeptide Fungal_trans PF04082.13 KEY69361.1 - 1.5e-12 46.9 0.0 3.1e-12 45.9 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY69361.1 - 4.2e-08 32.9 10.8 8.7e-08 31.9 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.1 KEY69362.1 - 1.3e-29 101.9 8.5 2.4e-09 37.0 0.2 5.8 2 2 3 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 KEY69362.1 - 2.5e-28 97.1 1.7 1.8e-05 24.4 0.0 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 KEY69362.1 - 2.3e-08 33.2 3.2 0.0017 17.9 0.0 5.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEY69362.1 - 1.4e-07 30.8 1.8 0.011 15.5 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEY69362.1 - 3.6e-07 29.7 0.2 0.0011 18.5 0.0 4.3 3 2 1 4 4 4 1 TPR repeat TPR_8 PF13181.1 KEY69362.1 - 6.8e-07 28.6 0.0 0.084 12.6 0.0 5.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 KEY69362.1 - 2e-05 24.5 3.1 6.4 7.5 0.3 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat AAA_22 PF13401.1 KEY69362.1 - 9e-05 22.6 0.0 0.00027 21.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain TPR_14 PF13428.1 KEY69362.1 - 0.00017 21.9 4.0 5.8 7.8 0.0 6.7 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEY69362.1 - 0.0003 20.2 0.6 0.061 12.9 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 KEY69362.1 - 0.00052 19.8 0.6 7.9 6.4 0.0 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Arylesterase PF01731.15 KEY69362.1 - 0.00094 19.1 0.0 0.0028 17.6 0.0 1.8 1 0 0 1 1 1 1 Arylesterase TPR_16 PF13432.1 KEY69362.1 - 0.0011 19.5 2.6 4.2 8.1 0.0 4.1 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEY69362.1 - 0.0016 18.7 1.0 0.86 9.9 0.0 4.3 3 1 3 6 6 5 1 Tetratricopeptide repeat Apc3 PF12895.2 KEY69362.1 - 0.0025 17.9 0.1 0.054 13.6 0.0 3.0 2 1 1 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 NB-ARC PF00931.17 KEY69362.1 - 0.0026 16.6 0.0 0.69 8.7 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain PGAP1 PF07819.8 KEY69362.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein TPR_17 PF13431.1 KEY69362.1 - 0.28 11.4 4.1 27 5.3 0.0 5.0 6 0 0 6 6 4 0 Tetratricopeptide repeat GcpE PF04551.9 KEY69362.1 - 0.33 9.7 0.0 0.51 9.0 0.0 1.2 1 0 0 1 1 1 0 GcpE protein Peptidase_M14 PF00246.19 KEY69363.1 - 2.1e-41 142.3 0.1 2.9e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Asparaginase_II PF06089.7 KEY69364.1 - 3e-107 358.0 0.0 3.3e-107 357.9 0.0 1.0 1 0 0 1 1 1 1 L-asparaginase II Lipase_GDSL_2 PF13472.1 KEY69365.1 - 3.3e-14 53.4 0.4 4.3e-14 53.0 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KEY69365.1 - 1.5e-12 47.8 0.3 2.4e-12 47.1 0.2 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF1349 PF07081.6 KEY69366.1 - 2.4e-20 72.6 0.0 5.7e-20 71.4 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) GMC_oxred_N PF00732.14 KEY69367.1 - 1.8e-54 184.8 0.0 2.7e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY69367.1 - 1.9e-33 115.8 0.0 1.1e-32 113.2 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 KEY69367.1 - 8.9e-06 24.8 1.1 0.00031 19.7 0.8 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEY69367.1 - 8.4e-05 22.7 0.0 0.75 9.8 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY69367.1 - 0.00042 20.2 0.1 0.0013 18.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KEY69367.1 - 0.00066 19.6 0.1 0.35 10.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEY69367.1 - 0.00095 18.1 0.0 0.032 13.0 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KEY69367.1 - 0.017 13.6 0.1 0.036 12.5 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 KEY69367.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.13 KEY69367.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.22 KEY69367.1 - 0.14 12.5 0.2 0.32 11.4 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_7 PF00840.15 KEY69368.1 - 2.4e-104 349.1 12.0 1.5e-87 293.7 9.5 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 7 NAD_binding_10 PF13460.1 KEY69370.1 - 3.3e-06 27.2 0.0 1.3e-05 25.3 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KEY69370.1 - 3.2e-05 23.2 0.0 4.9e-05 22.6 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family zf-3CxxC PF13695.1 KEY69371.1 - 3.7e-28 97.6 1.0 3.7e-28 97.6 0.7 1.4 2 0 0 2 2 2 1 Zinc-binding domain Methyltransf_31 PF13847.1 KEY69372.1 - 2.3e-24 85.7 0.0 3.9e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY69372.1 - 5.7e-24 84.4 0.0 1.8e-23 82.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY69372.1 - 1.1e-17 64.1 0.0 1.8e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY69372.1 - 7e-16 58.5 0.0 1.4e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY69372.1 - 7.5e-15 55.4 0.0 2.4e-14 53.8 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY69372.1 - 1.2e-14 53.9 0.0 2.4e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEY69372.1 - 2.2e-13 50.4 0.0 1.2e-12 48.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY69372.1 - 2.5e-11 43.6 0.0 5.5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KEY69372.1 - 9.5e-10 38.3 0.0 1.8e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 KEY69372.1 - 4.3e-08 32.7 0.0 9.3e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KEY69372.1 - 2.9e-05 23.1 0.0 7.2e-05 21.9 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase MetW PF07021.7 KEY69372.1 - 0.00035 19.9 0.0 0.00073 18.9 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.10 KEY69372.1 - 0.00075 19.1 0.0 0.0036 16.9 0.0 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase RrnaAD PF00398.15 KEY69372.1 - 0.00082 18.4 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase FtsJ PF01728.14 KEY69372.1 - 0.0031 17.5 0.0 0.0083 16.1 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase NodS PF05401.6 KEY69372.1 - 0.02 14.2 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_2 PF00891.13 KEY69372.1 - 0.095 11.8 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 O-methyltransferase CMAS PF02353.15 KEY69372.1 - 0.096 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MFS_1 PF07690.11 KEY69376.1 - 2.5e-31 108.6 32.3 2.5e-31 108.6 22.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily PHTB1_N PF14727.1 KEY69377.1 - 0.031 13.2 0.0 0.031 13.2 0.0 1.0 1 0 0 1 1 1 0 PTHB1 N-terminus Cutinase PF01083.17 KEY69378.1 - 4.2e-32 111.3 0.0 5.9e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 KEY69378.1 - 0.00051 19.8 0.0 0.00068 19.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 KEY69378.1 - 0.001 18.5 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.2 KEY69378.1 - 0.0025 17.7 0.1 0.0051 16.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KEY69378.1 - 0.0033 17.6 0.0 0.0043 17.3 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 KEY69378.1 - 0.022 14.3 0.0 0.024 14.1 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold SH3_7 PF12914.2 KEY69378.1 - 0.026 14.3 0.1 3.7 7.4 0.0 2.3 2 0 0 2 2 2 0 SH3 domain of SH3b2 type VirJ PF06057.6 KEY69378.1 - 0.031 14.0 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF2974 PF11187.3 KEY69378.1 - 0.053 12.8 0.0 0.069 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Bac_rhamnosid PF05592.6 KEY69379.1 - 5.2e-30 104.1 0.0 9.4e-23 80.2 0.0 2.3 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 KEY69379.1 - 0.0038 16.0 0.1 0.0057 15.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF608 UDPGT PF00201.13 KEY69380.1 - 6.9e-15 54.5 0.0 1e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 KEY69380.1 - 0.00034 20.3 0.0 0.00066 19.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Fructosamin_kin PF03881.9 KEY69381.1 - 1.2e-37 129.5 0.0 1.5e-37 129.1 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KEY69381.1 - 1.7e-06 27.9 0.0 2.8e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family dCMP_cyt_deam_1 PF00383.17 KEY69382.1 - 6.9e-15 54.5 0.1 1e-14 54.0 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 KEY69382.1 - 0.0002 21.0 0.0 0.00025 20.7 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain XOO_2897-deam PF14440.1 KEY69382.1 - 0.1 12.3 0.3 0.29 10.8 0.2 1.8 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase WD40 PF00400.27 KEY69383.1 - 2.2e-08 33.6 0.0 2.9 7.9 0.0 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat NACHT PF05729.7 KEY69383.1 - 1.7e-06 27.7 0.0 3.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.9 KEY69383.1 - 2.1e-05 23.9 0.0 5.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KEY69383.1 - 0.00028 20.5 0.0 0.00061 19.4 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KEY69383.1 - 0.061 13.0 0.1 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family APS_kinase PF01583.15 KEY69383.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_pol_L_2 PF13656.1 KEY69384.1 - 1.9e-30 104.1 0.0 2.5e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KEY69384.1 - 2.4e-10 39.3 0.0 3.2e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_60s PF00428.14 KEY69384.1 - 1.5 9.3 12.5 3.1 8.2 8.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Complex1_LYR_2 PF13233.1 KEY69385.1 - 1e-06 29.1 0.1 1.3e-06 28.8 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 KEY69385.1 - 7.1e-06 26.1 0.2 1.3e-05 25.3 0.1 1.6 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KEY69385.1 - 2.5e-05 23.9 0.2 5.2e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) G10 PF01125.12 KEY69386.1 - 3.8e-60 201.6 3.2 4.2e-60 201.5 2.2 1.0 1 0 0 1 1 1 1 G10 protein zf-C2H2 PF00096.21 KEY69387.1 - 0.054 13.8 0.7 0.054 13.8 0.5 3.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY69387.1 - 4.3 7.8 14.8 4.6 7.8 0.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger EST1_DNA_bind PF10373.4 KEY69388.1 - 7.8e-49 166.3 0.5 1.6e-48 165.3 0.2 1.6 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 KEY69388.1 - 6.4e-22 77.9 0.4 1.3e-21 76.9 0.3 1.6 1 0 0 1 1 1 1 Telomerase activating protein Est1 PfkB PF00294.19 KEY69389.1 - 1.1e-65 221.7 0.0 1.2e-65 221.5 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KEY69389.1 - 0.058 12.5 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Ribosomal_L2_C PF03947.13 KEY69390.1 - 2.9e-38 130.6 3.5 4e-38 130.1 2.4 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KEY69390.1 - 0.03 14.2 0.6 1.3 9.0 0.4 2.5 1 1 0 1 1 1 0 Ribosomal Proteins L2, RNA binding domain SpoA PF01052.15 KEY69390.1 - 0.12 12.0 0.1 0.31 10.6 0.0 1.7 2 0 0 2 2 2 0 Surface presentation of antigens (SPOA) WHIM1 PF15612.1 KEY69391.1 - 0.0031 17.3 0.0 0.0083 16.0 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Daxx PF03344.10 KEY69391.1 - 0.91 7.9 24.1 0.46 8.8 15.4 1.4 1 1 0 1 1 1 0 Daxx Family DUF1770 PF08589.5 KEY69392.1 - 2e-27 95.6 1.1 2.5e-27 95.4 0.7 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) eRF1_2 PF03464.10 KEY69393.1 - 6.7e-47 159.1 0.1 1.3e-46 158.1 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KEY69393.1 - 5.1e-41 139.4 0.5 1.1e-40 138.4 0.4 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KEY69393.1 - 2.2e-28 98.4 0.0 4.6e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 GMP_PDE_delta PF05351.6 KEY69393.1 - 0.0093 15.7 0.5 0.03 14.1 0.4 1.8 1 0 0 1 1 1 1 GMP-PDE, delta subunit PH PF00169.24 KEY69394.1 - 2e-05 24.7 0.0 6.8e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 PH domain GRAM PF02893.15 KEY69394.1 - 0.013 14.9 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 GRAM domain Phage_int_SAM_4 PF13495.1 KEY69394.1 - 0.094 13.0 0.2 0.24 11.7 0.1 1.7 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DUF3074 PF11274.3 KEY69395.1 - 2.9e-54 183.5 6.6 1.3e-52 178.1 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3074) CAF-1_p150 PF11600.3 KEY69395.1 - 0.0022 17.4 42.5 0.0058 16.0 29.5 1.7 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2428 PF10350.4 KEY69396.1 - 9.8e-62 208.2 0.0 1.9e-61 207.3 0.0 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 KEY69396.1 - 6.7e-12 44.4 11.3 0.042 13.9 0.0 6.8 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.1 KEY69396.1 - 2.2e-07 31.0 6.8 0.011 16.0 0.1 5.3 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 KEY69396.1 - 2e-06 28.0 9.9 0.00044 20.6 0.2 6.1 5 0 0 5 5 5 1 HEAT-like repeat DUF3385 PF11865.3 KEY69396.1 - 0.063 13.1 0.4 0.48 10.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Ribosomal_L1 PF00687.16 KEY69397.1 - 3.8e-50 170.2 0.2 4.6e-50 169.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ndr PF03096.9 KEY69397.1 - 0.1 11.0 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 Ndr family Arf PF00025.16 KEY69398.1 - 8.9e-58 194.3 0.2 5.8e-56 188.4 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.15 KEY69398.1 - 1.3e-07 30.6 0.0 2.5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit Ras PF00071.17 KEY69398.1 - 2.3e-06 27.0 0.0 3.4e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KEY69398.1 - 2.5e-05 23.5 0.0 3.4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KEY69398.1 - 9.5e-05 21.6 0.0 0.00014 21.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KEY69398.1 - 0.0011 19.4 0.0 0.0017 18.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 KEY69398.1 - 0.03 13.0 0.1 0.072 11.8 0.1 1.5 1 1 0 1 1 1 0 ArgK protein ATP-synt_C PF00137.16 KEY69399.1 - 1e-26 92.5 24.6 1.2e-15 57.1 7.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.3 KEY69399.1 - 0.0053 16.1 0.4 3.1 7.3 0.0 2.5 2 0 0 2 2 2 2 T-cell surface glycoprotein CD3 zeta chain MerC PF03203.9 KEY69399.1 - 8.8 6.7 11.6 3.3e+02 1.6 8.0 2.8 1 1 0 1 1 1 0 MerC mercury resistance protein Pep3_Vps18 PF05131.9 KEY69400.1 - 1.1e-42 144.9 0.5 2.1e-42 144.0 0.1 1.7 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 KEY69400.1 - 5.3e-11 42.2 6.1 1.5e-07 31.0 0.0 3.6 3 0 0 3 3 3 2 Region in Clathrin and VPS DUF2175 PF09943.4 KEY69400.1 - 0.00013 21.9 0.1 0.0037 17.2 0.0 2.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_2 PF13639.1 KEY69400.1 - 0.00017 21.3 0.3 0.00017 21.3 0.2 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KEY69400.1 - 0.00086 18.9 0.3 0.00086 18.9 0.2 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEY69400.1 - 0.028 14.4 0.4 0.076 13.0 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1086 PF06461.6 KEY69400.1 - 0.044 13.5 0.1 0.085 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) zf-C3HC4 PF00097.20 KEY69400.1 - 1.3 8.7 4.1 0.28 10.8 0.1 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Methyltransf_23 PF13489.1 KEY69401.1 - 1.2e-15 57.5 0.0 2.2e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY69401.1 - 1.6e-09 37.5 0.0 3.8e-09 36.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY69401.1 - 1.7e-08 34.8 0.0 4.8e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY69401.1 - 2.6e-07 31.1 0.0 6.4e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY69401.1 - 2.9e-07 30.8 0.0 8e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KEY69401.1 - 0.00044 19.5 0.0 0.00068 18.9 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.12 KEY69401.1 - 0.0043 16.1 0.0 0.014 14.4 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 KEY69401.1 - 0.0054 17.0 0.0 0.018 15.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 KEY69401.1 - 0.015 15.3 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.9 KEY69401.1 - 0.018 14.3 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Thaumatin PF00314.12 KEY69401.1 - 0.021 14.2 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Thaumatin family DUF938 PF06080.7 KEY69401.1 - 0.027 14.0 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Ubie_methyltran PF01209.13 KEY69401.1 - 0.049 12.7 0.0 0.13 11.3 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Epimerase PF01370.16 KEY69402.1 - 1.2e-55 188.5 0.0 1.5e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEY69402.1 - 5.5e-22 77.7 0.0 7.2e-22 77.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KEY69402.1 - 8e-22 77.4 0.0 7.5e-21 74.2 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KEY69402.1 - 9.5e-22 77.1 0.1 9.8e-21 73.8 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 KEY69402.1 - 9.8e-21 73.8 0.0 1.3e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KEY69402.1 - 1.3e-08 35.0 0.0 1.9e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KEY69402.1 - 0.01 15.7 0.0 0.69 9.8 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Brix PF04427.13 KEY69403.1 - 1.2e-39 135.9 0.1 1.8e-39 135.4 0.1 1.2 1 0 0 1 1 1 1 Brix domain Nop14 PF04147.7 KEY69403.1 - 2.8 5.7 22.6 3.6 5.3 15.6 1.1 1 0 0 1 1 1 0 Nop14-like family NOC3p PF07540.6 KEY69404.1 - 9.4e-30 102.7 5.2 4.2e-29 100.6 0.0 3.4 3 1 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.12 KEY69404.1 - 3.2e-28 98.2 0.0 2.7e-27 95.2 0.0 2.3 2 0 0 2 2 2 1 CBF/Mak21 family DUF2360 PF10152.4 KEY69404.1 - 0.12 12.7 2.3 0.95 9.7 0.0 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) RNase_P_pop3 PF08228.6 KEY69405.1 - 4.2e-10 39.6 0.0 6.2e-07 29.3 0.0 2.1 2 0 0 2 2 2 2 RNase P subunit Pop3 GARS_A PF01071.14 KEY69406.1 - 2.2e-81 272.0 0.0 4.3e-81 271.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 KEY69406.1 - 1.5e-37 128.0 0.0 3.1e-36 123.8 0.0 2.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 KEY69406.1 - 1.4e-31 109.6 0.0 3.1e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 KEY69406.1 - 3e-24 84.9 0.9 7.8e-24 83.6 0.1 2.1 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 KEY69406.1 - 9.6e-18 64.2 0.9 3.8e-17 62.3 0.6 2.1 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 KEY69406.1 - 3.3e-10 39.9 0.0 7.3e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KEY69406.1 - 3.8e-08 32.4 0.0 8.1e-08 31.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KEY69406.1 - 4.6e-05 22.8 0.0 9.4e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KEY69406.1 - 0.00021 20.6 0.1 0.00042 19.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_2 PF08442.5 KEY69406.1 - 0.0013 18.1 0.1 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KEY69406.1 - 0.03 13.8 0.3 0.09 12.2 0.0 1.9 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KEY69406.1 - 0.046 13.5 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain UCH PF00443.24 KEY69407.1 - 4e-49 167.1 0.1 6.8e-49 166.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.3 KEY69407.1 - 1.3e-17 63.4 0.0 2.2e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH_1 PF13423.1 KEY69407.1 - 8.6e-17 61.5 0.0 1.8e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1546 PF07571.8 KEY69407.1 - 0.11 12.6 0.0 0.62 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) NRDE PF05742.7 KEY69407.1 - 0.15 11.3 0.0 0.35 10.1 0.0 1.5 1 0 0 1 1 1 0 NRDE protein DUF2457 PF10446.4 KEY69407.1 - 1.1 7.8 23.0 0.065 11.9 8.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 KEY69407.1 - 5.4 6.5 22.0 1.4 8.4 8.2 2.3 2 0 0 2 2 2 0 Nucleoplasmin PRCC PF10253.4 KEY69409.1 - 1.6e-35 123.4 1.0 1.6e-35 123.4 0.7 2.5 3 0 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting DUF524 PF04411.7 KEY69409.1 - 0.17 11.6 0.2 0.3 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF524) Pol_alpha_B_N PF08418.5 KEY69409.1 - 4.1 6.8 7.5 0.4 10.1 0.5 2.3 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal SIN1 PF05422.7 KEY69410.1 - 5e-37 127.6 0.0 1.9e-17 62.9 0.0 3.3 3 1 0 3 3 3 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 KEY69410.1 - 0.0018 18.1 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 GLUT4 regulating protein TUG GTP_cyclohydro2 PF00925.15 KEY69410.1 - 0.083 12.1 0.1 0.25 10.5 0.0 1.8 2 0 0 2 2 2 0 GTP cyclohydrolase II RBD PF02196.10 KEY69410.1 - 0.1 12.3 0.2 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 Raf-like Ras-binding domain Spore_coat_CotO PF14153.1 KEY69410.1 - 1.2 8.5 5.7 0.41 10.0 0.4 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Baculo_PEP_C PF04513.7 KEY69411.1 - 0.039 13.7 0.0 2.2 8.1 0.0 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.6 KEY69411.1 - 0.058 13.4 0.0 0.86 9.6 0.1 2.2 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) FliE PF02049.13 KEY69411.1 - 0.12 12.4 3.0 1.4 8.9 0.1 2.6 2 1 1 3 3 3 0 Flagellar hook-basal body complex protein FliE HalX PF08663.5 KEY69411.1 - 0.19 11.7 2.0 0.28 11.1 0.4 2.1 2 0 0 2 2 2 0 HalX domain Tape_meas_lam_C PF09718.5 KEY69411.1 - 0.24 11.3 13.3 0.67 9.9 0.5 4.0 1 1 2 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF883 PF05957.8 KEY69411.1 - 0.35 11.2 2.9 6.7 7.1 2.2 2.4 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PMEI PF04043.10 KEY69411.1 - 0.53 10.1 5.1 2.7 7.8 0.1 2.9 1 1 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor HsbA PF12296.3 KEY69411.1 - 1.2 8.9 8.8 4 7.3 0.8 3.0 1 1 1 3 3 3 0 Hydrophobic surface binding protein A TrbC PF04956.8 KEY69411.1 - 3.8 7.5 10.4 1.2 9.1 0.1 4.0 1 1 3 4 4 4 0 TrbC/VIRB2 family BRF1 PF07741.8 KEY69412.1 - 0.012 15.8 7.8 0.012 15.8 5.4 2.7 3 0 0 3 3 3 0 Brf1-like TBP-binding domain Zip PF02535.17 KEY69413.1 - 1.4e-37 129.4 18.6 2.4e-29 102.3 7.2 3.0 2 1 0 2 2 2 2 ZIP Zinc transporter WD40 PF00400.27 KEY69414.1 - 1.2e-53 177.1 19.4 2.7e-11 42.8 0.5 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 KEY69414.1 - 1.1e-12 47.4 0.6 2.3e-12 46.4 0.4 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 KEY69414.1 - 7.1e-10 37.6 9.3 0.0057 14.8 0.1 5.8 1 1 4 5 5 5 4 Nucleoporin Nup120/160 F-box PF00646.28 KEY69414.1 - 2.4e-06 27.0 2.0 5.3e-06 25.9 1.4 1.6 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 KEY69414.1 - 0.00096 18.6 4.4 1.4 8.2 0.1 4.3 1 1 2 4 4 4 1 PQQ-like domain PQQ_3 PF13570.1 KEY69414.1 - 0.024 14.8 3.7 61 4.0 0.0 5.3 5 2 0 5 5 5 0 PQQ-like domain E1_dh PF00676.15 KEY69415.1 - 3.2e-113 377.4 0.2 4e-113 377.0 0.2 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KEY69415.1 - 0.00076 18.4 0.1 0.0015 17.4 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase DNA_ligase_A_M PF01068.16 KEY69416.1 - 6.5e-58 195.4 0.9 1.3e-46 158.5 0.3 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KEY69416.1 - 6e-51 172.7 0.0 1.1e-50 171.8 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KEY69416.1 - 1.3e-28 99.2 0.0 4.5e-28 97.4 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Voltage_CLC PF00654.15 KEY69417.1 - 1.4e-90 303.8 27.3 2.2e-90 303.2 18.9 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 KEY69417.1 - 6.4e-05 22.6 0.0 0.04 13.7 0.0 2.5 2 0 0 2 2 2 2 CBS domain Gly-zipper_OmpA PF13436.1 KEY69417.1 - 0.12 12.0 0.7 0.73 9.5 0.0 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Neurochondrin PF05536.6 KEY69418.1 - 1e-95 321.1 1.1 1.4e-94 317.3 0.7 2.1 1 1 0 1 1 1 1 Neurochondrin RIX1 PF08167.7 KEY69418.1 - 1.9e-05 24.3 3.1 0.012 15.2 0.0 3.4 4 0 0 4 4 4 2 rRNA processing/ribosome biogenesis DUF972 PF06156.8 KEY69419.1 - 2.3 8.6 4.7 3.4 8.0 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF972) MFS_1 PF07690.11 KEY69420.1 - 4.5e-53 180.2 33.2 5.3e-47 160.2 12.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEY69420.1 - 5.8e-15 54.6 9.9 1.2e-08 33.8 0.1 2.9 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 KEY69420.1 - 4.1e-12 45.4 7.2 6.9e-12 44.6 3.5 2.0 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 KEY69420.1 - 0.021 14.6 0.8 0.12 12.1 0.5 2.5 1 1 0 1 1 1 0 MFS_1 like family MFS_3 PF05977.8 KEY69420.1 - 0.022 12.9 16.9 0.02 13.0 5.8 2.4 2 0 0 2 2 2 0 Transmembrane secretion effector Ras PF00071.17 KEY69421.1 - 4.4e-52 175.7 0.0 5.1e-52 175.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEY69421.1 - 1e-15 58.2 0.0 1.7e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEY69421.1 - 2.8e-06 26.6 0.0 3.7e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Arginase PF00491.16 KEY69422.1 - 1.9e-87 293.0 0.0 2.3e-87 292.8 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KEY69422.1 - 0.067 13.3 0.3 0.27 11.4 0.1 1.7 1 1 1 2 2 2 0 UPF0489 domain RRM_6 PF14259.1 KEY69423.1 - 4.1e-38 129.1 0.0 1.2e-08 34.8 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEY69423.1 - 1.7e-37 126.9 0.1 9.8e-12 44.3 0.1 5.2 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY69423.1 - 5.3e-21 74.2 0.7 0.0002 21.1 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 KEY69423.1 - 3.9e-14 51.9 5.0 3.9e-14 51.9 3.5 3.7 2 0 0 2 2 2 1 Putative RRM domain RRM_3 PF08777.6 KEY69423.1 - 0.00044 20.0 0.2 0.031 14.0 0.1 2.6 2 0 0 2 2 2 1 RNA binding motif RNA_bind PF08675.6 KEY69423.1 - 0.031 14.2 0.0 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 RNA binding domain Nup35_RRM_2 PF14605.1 KEY69423.1 - 0.037 13.8 0.1 20 5.0 0.0 3.3 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif His_Phos_2 PF00328.17 KEY69424.1 - 8.3e-24 84.5 0.0 7.3e-23 81.4 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 KEY69424.1 - 0.0046 17.0 0.0 0.013 15.6 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Abhydrolase_6 PF12697.2 KEY69425.1 - 3.6e-06 27.0 0.2 1e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family LCAT PF02450.10 KEY69425.1 - 0.0016 17.5 0.0 0.0025 16.8 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 KEY69425.1 - 0.058 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.8 KEY69425.1 - 0.15 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein MIF PF01187.13 KEY69428.1 - 3.3e-11 43.2 0.0 5.6e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Gtr1_RagA PF04670.7 KEY69429.1 - 9.4e-70 234.3 0.1 1.2e-69 233.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KEY69429.1 - 2.5e-05 24.7 0.0 0.00072 20.0 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KEY69429.1 - 0.0019 17.4 0.0 0.0039 16.4 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KEY69429.1 - 0.045 12.4 0.1 0.076 11.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Apc4 PF12896.2 KEY69430.1 - 4.6e-54 182.8 0.1 7.7e-54 182.1 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Adap_comp_sub PF00928.16 KEY69431.1 - 1.3e-16 60.5 0.0 2.1e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KEY69431.1 - 2.9e-08 33.5 0.1 4.6e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2420 PF10336.4 KEY69432.1 - 4.3e-07 29.5 0.1 7e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Mg_trans_NIPA PF05653.9 KEY69433.1 - 5.9e-106 353.7 11.7 7.2e-106 353.5 8.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KEY69433.1 - 6.7e-08 32.7 2.6 6.7e-08 32.7 1.8 3.1 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KEY69433.1 - 7.6e-05 22.7 6.5 7.6e-05 22.7 4.5 3.3 2 1 1 3 3 3 2 EamA-like transporter family Ribosomal_S3_C PF00189.15 KEY69434.1 - 1.2e-16 60.6 0.1 2.4e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 KEY69434.1 - 2.4e-12 46.2 0.1 4.6e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 KEY69434.1 - 0.06 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Myotub-related PF06602.9 KEY69435.1 - 4.5e-128 426.9 0.1 5.6e-128 426.6 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 KEY69435.1 - 0.014 15.6 0.0 0.05 13.8 0.0 2.0 1 0 0 1 1 1 0 Tyrosine phosphatase family G-alpha PF00503.15 KEY69435.1 - 0.036 12.7 0.1 0.061 12.0 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit DUF3156 PF11354.3 KEY69435.1 - 0.086 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3156) DSPc PF00782.15 KEY69435.1 - 0.19 11.3 0.5 0.53 9.8 0.0 1.9 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain B3_4 PF03483.12 KEY69436.1 - 1.7e-27 96.0 0.0 3.5e-27 94.9 0.0 1.6 1 1 0 1 1 1 1 B3/4 domain B5 PF03484.10 KEY69436.1 - 2.8e-16 59.1 0.0 2e-12 46.7 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain HEAT PF02985.17 KEY69437.1 - 1.3e-42 140.0 15.8 0.0029 17.5 0.1 13.2 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 KEY69437.1 - 4.6e-30 103.7 2.1 3.5e-08 33.6 0.0 7.4 3 3 3 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.2 KEY69437.1 - 5.6e-11 42.6 5.5 0.015 15.6 0.1 7.5 5 2 4 9 9 9 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KEY69437.1 - 6.1e-10 39.2 11.7 0.22 12.0 0.0 9.1 7 3 3 10 10 10 2 HEAT-like repeat Adaptin_N PF01602.15 KEY69437.1 - 2.7e-08 32.5 8.8 0.0016 16.8 0.1 4.9 3 2 2 6 6 6 4 Adaptin N terminal region CLASP_N PF12348.3 KEY69437.1 - 1.1e-05 24.9 2.9 2.8 7.2 0.0 4.9 4 3 1 5 5 5 3 CLASP N terminal DUF2435 PF10363.4 KEY69437.1 - 6.1e-05 22.8 4.4 0.044 13.6 0.2 4.6 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) Cnd3 PF12719.2 KEY69437.1 - 0.008 15.1 0.8 0.25 10.2 0.1 3.0 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain MadL PF03817.8 KEY69437.1 - 0.03 14.1 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 Malonate transporter MadL subunit RIX1 PF08167.7 KEY69437.1 - 0.039 13.6 0.2 1.4 8.5 0.0 3.2 3 1 1 4 4 4 0 rRNA processing/ribosome biogenesis Arm PF00514.18 KEY69437.1 - 0.051 13.4 5.6 1.7 8.5 0.0 4.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.4 KEY69437.1 - 0.13 10.4 3.8 0.63 8.2 0.0 2.8 2 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit Methyltransf_18 PF12847.2 KEY69438.1 - 3.1e-17 63.1 0.0 5e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY69438.1 - 6e-09 35.6 0.0 1.2e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY69438.1 - 3.5e-08 33.4 0.2 5.8e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY69438.1 - 3e-07 30.2 0.0 3.6e-06 26.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY69438.1 - 1.1e-06 29.0 0.0 1e-05 25.9 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY69438.1 - 9.6e-05 22.8 0.0 0.0002 21.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY69438.1 - 0.00018 21.7 0.0 0.00027 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY69438.1 - 0.00068 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain AdoMet_MTase PF07757.8 KEY69438.1 - 0.0024 17.9 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MetW PF07021.7 KEY69438.1 - 0.015 14.7 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 KEY69438.1 - 0.035 13.8 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 KEY69438.1 - 0.051 12.6 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase eIF-6 PF01912.13 KEY69439.1 - 4.6e-83 277.2 1.2 6.6e-83 276.6 0.8 1.2 1 0 0 1 1 1 1 eIF-6 family Ycf1 PF05758.7 KEY69440.1 - 0.31 8.6 4.6 3.1 5.3 0.6 2.2 2 0 0 2 2 2 0 Ycf1 Pox_Ag35 PF03286.9 KEY69440.1 - 5.3 6.5 10.5 16 4.9 7.3 1.8 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Peptidase_C65 PF10275.4 KEY69441.1 - 1.9e-58 197.6 0.0 2.6e-58 197.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 KEY69441.1 - 0.0036 17.8 0.0 2.9 8.4 0.0 2.5 2 0 0 2 2 2 2 OTU-like cysteine protease Ferric_reduct PF01794.14 KEY69442.1 - 4.4e-17 62.3 17.6 4.3e-16 59.1 11.2 2.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KEY69442.1 - 7.5e-06 25.7 0.0 0.036 13.9 0.0 3.0 3 0 0 3 3 3 2 FAD-binding domain NAD_binding_6 PF08030.7 KEY69442.1 - 5.8e-05 23.0 0.0 0.22 11.4 0.0 2.6 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KEY69442.1 - 0.00018 22.0 0.0 0.00042 20.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Guanylate_kin PF00625.16 KEY69443.1 - 2.8e-61 206.1 0.0 3.3e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 KEY69443.1 - 1.2e-05 25.2 0.0 4.3e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEY69443.1 - 7.1e-05 23.1 0.0 0.0002 21.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEY69443.1 - 0.0011 19.7 0.0 0.0038 18.0 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 KEY69443.1 - 0.0012 18.9 0.0 0.0027 17.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KEY69443.1 - 0.0013 17.9 0.0 0.0023 17.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 KEY69443.1 - 0.0086 15.9 0.0 0.014 15.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEY69443.1 - 0.0095 15.9 0.0 0.015 15.3 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 KEY69443.1 - 0.013 15.8 0.0 0.023 14.9 0.0 1.7 1 1 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 KEY69443.1 - 0.019 14.6 0.0 0.064 12.9 0.0 1.9 1 1 0 1 1 1 0 Archaeal ATPase AAA_28 PF13521.1 KEY69443.1 - 0.025 14.5 0.1 0.096 12.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KEY69443.1 - 0.06 13.0 0.1 0.1 12.2 0.0 1.6 1 1 0 1 1 1 0 NTPase AAA PF00004.24 KEY69443.1 - 0.077 13.1 0.2 0.32 11.1 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KEY69443.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 KEY69443.1 - 0.12 11.9 0.1 0.59 9.6 0.1 1.9 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KEY69443.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.7 KEY69443.1 - 0.15 11.7 0.0 0.57 9.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Sulfate_transp PF00916.15 KEY69444.1 - 5.3e-73 245.4 8.9 9e-73 244.6 6.2 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KEY69444.1 - 4.3e-32 109.6 3.0 4.3e-32 109.6 2.1 2.8 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KEY69444.1 - 4.7e-09 35.6 0.0 8.9e-09 34.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KEY69444.1 - 0.059 13.3 0.0 0.2 11.7 0.0 1.9 1 0 0 1 1 1 0 STAS domain DUF1189 PF06691.6 KEY69444.1 - 0.34 10.1 6.4 0.94 8.7 4.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) adh_short PF00106.20 KEY69446.1 - 2e-17 63.5 0.0 2.8e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY69446.1 - 2.9e-13 50.1 0.0 3.7e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MucB_RseB PF03888.9 KEY69446.1 - 0.071 12.1 0.0 0.097 11.6 0.0 1.1 1 0 0 1 1 1 0 MucB/RseB family LysM PF01476.15 KEY69447.1 - 1.6e-13 50.3 0.0 2.5e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 LysM domain HEAT_EZ PF13513.1 KEY69448.1 - 4.6e-19 68.3 14.0 1e-07 32.2 0.0 9.2 8 2 3 11 11 10 4 HEAT-like repeat HEAT PF02985.17 KEY69448.1 - 3e-14 51.7 9.2 0.00055 19.7 0.1 8.8 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.1 KEY69448.1 - 4e-13 49.4 16.8 0.0035 17.5 0.6 8.0 3 2 4 7 7 7 5 HEAT repeats Vac14_Fab1_bd PF12755.2 KEY69448.1 - 1.5e-07 31.7 0.0 0.35 11.2 0.0 5.3 4 1 1 5 5 4 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KEY69448.1 - 1.7e-06 26.7 1.9 0.15 10.3 0.0 4.6 3 1 1 5 5 5 3 Adaptin N terminal region IBN_N PF03810.14 KEY69448.1 - 3.8e-05 23.5 0.1 0.00049 19.9 0.0 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.3 KEY69448.1 - 0.00015 21.1 0.0 0.45 9.8 0.0 4.2 4 1 0 5 5 5 1 CLASP N terminal ParcG PF10274.4 KEY69448.1 - 0.00017 21.5 0.1 0.23 11.3 0.0 3.5 3 1 1 4 4 4 1 Parkin co-regulated protein Arm PF00514.18 KEY69448.1 - 0.0004 20.1 0.9 0.88 9.4 0.0 4.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 KEY69448.1 - 0.0015 18.4 2.0 0.98 9.2 0.0 4.6 5 1 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.9 KEY69448.1 - 0.012 14.8 0.8 15 4.5 1.4 3.7 1 1 1 2 2 2 0 V-ATPase subunit H Pico_P2B PF01552.12 KEY69448.1 - 0.02 15.0 0.0 0.12 12.5 0.0 2.3 2 0 0 2 2 1 0 Picornavirus 2B protein MMS19_C PF12460.3 KEY69448.1 - 0.093 11.4 3.8 11 4.6 0.0 3.5 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal DUF747 PF05346.6 KEY69449.1 - 4e-129 430.4 4.6 5.3e-129 430.0 3.2 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family HemY_N PF07219.8 KEY69449.1 - 0.29 10.6 6.0 4.7 6.7 0.3 2.5 2 0 0 2 2 2 0 HemY protein N-terminus DLH PF01738.13 KEY69450.1 - 5.4e-27 94.4 0.0 6.6e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KEY69450.1 - 0.00012 21.8 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family zf-U1 PF06220.7 KEY69451.1 - 4.1e-07 29.4 2.0 6.3e-07 28.8 1.4 1.3 1 0 0 1 1 1 1 U1 zinc finger CCDC84 PF14968.1 KEY69451.1 - 0.054 12.9 1.6 0.077 12.4 1.1 1.4 1 1 0 1 1 1 0 Coiled coil protein 84 DUF3166 PF11365.3 KEY69451.1 - 0.067 13.6 0.2 0.067 13.6 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3166) PIR PF00399.14 KEY69452.1 - 2.7e-34 115.3 56.4 3.7e-06 26.0 0.8 9.5 9 0 0 9 9 9 8 Yeast PIR protein repeat Peptidase_M36 PF02128.10 KEY69453.1 - 3.4e-147 490.2 0.7 4.3e-147 489.8 0.5 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 KEY69453.1 - 1.4e-13 50.1 0.9 1.4e-13 50.1 0.6 2.4 3 0 0 3 3 3 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_MA_2 PF13485.1 KEY69453.1 - 0.03 14.3 0.0 0.077 13.0 0.0 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily Pentapeptide_3 PF13576.1 KEY69453.1 - 0.14 12.0 4.6 0.15 11.9 1.8 2.0 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) Gpi16 PF04113.9 KEY69454.1 - 1.6e-233 775.8 0.0 2.1e-233 775.4 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.10 KEY69455.1 - 4.2e-71 239.4 1.7 5.3e-71 239.1 1.2 1.0 1 0 0 1 1 1 1 LUC7 N_terminus ERM PF00769.14 KEY69455.1 - 0.033 13.7 0.5 0.047 13.2 0.4 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF1241 PF06840.6 KEY69455.1 - 0.041 13.1 0.3 0.11 11.7 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1241) MCPsignal PF00015.16 KEY69455.1 - 0.057 12.9 0.1 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CDC27 PF09507.5 KEY69456.1 - 9.6e-05 21.7 22.6 9.6e-05 21.7 15.7 1.5 2 0 0 2 2 2 1 DNA polymerase subunit Cdc27 CAF-1_p150 PF11600.3 KEY69456.1 - 0.093 12.0 19.7 0.18 11.1 13.6 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TFIIA PF03153.8 KEY69456.1 - 1.2 9.0 15.5 2.1 8.1 10.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hex_IIIa PF02455.11 KEY69456.1 - 1.5 7.3 6.7 2 7.0 4.7 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) PAT1 PF09770.4 KEY69456.1 - 2.9 5.9 25.5 4.9 5.2 17.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nuc_deoxyrib_tr PF05014.10 KEY69457.1 - 1.9e-05 24.5 0.0 2.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase CBM_1 PF00734.13 KEY69459.1 - 2.5e-12 46.2 12.0 2.5e-12 46.2 8.3 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain BNR PF02012.15 KEY69459.1 - 1.7e-05 23.9 37.8 0.076 12.8 0.1 9.7 10 0 0 10 10 10 5 BNR/Asp-box repeat Toxin_7 PF05980.7 KEY69459.1 - 0.0092 15.9 2.3 0.016 15.2 1.6 1.4 1 0 0 1 1 1 1 Toxin 7 Saccharop_dh PF03435.13 KEY69460.1 - 1.8e-50 172.0 0.2 3.5e-16 59.1 0.0 3.0 1 1 2 3 3 3 3 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KEY69460.1 - 2.3e-06 27.7 0.0 3.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 KEY69460.1 - 5.4e-05 23.3 0.0 7.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 KEY69460.1 - 0.016 14.5 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family NAD_binding_7 PF13241.1 KEY69460.1 - 0.019 15.2 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 3Beta_HSD PF01073.14 KEY69460.1 - 0.15 10.6 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sugar_tr PF00083.19 KEY69461.1 - 9.4e-84 281.5 25.1 1.2e-83 281.2 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY69461.1 - 1.8e-43 148.6 56.6 6.6e-35 120.4 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Bac_luciferase PF00296.15 KEY69461.1 - 0.021 13.9 0.1 0.045 12.8 0.1 1.5 1 0 0 1 1 1 0 Luciferase-like monooxygenase Nitroreductase PF00881.19 KEY69461.1 - 0.061 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Nitroreductase family TRI12 PF06609.8 KEY69461.1 - 0.28 9.3 15.3 0.0049 15.1 1.7 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_2_C PF02836.12 KEY69463.1 - 1.6e-97 326.0 0.1 2.8e-97 325.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 KEY69463.1 - 1.4e-54 184.9 0.1 2.3e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 KEY69463.1 - 9e-49 165.2 0.2 1.6e-48 164.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KEY69463.1 - 2.3e-12 47.3 0.0 7.5e-12 45.6 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 KEY69463.1 - 0.0044 17.2 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain BiPBP_C PF06832.7 KEY69463.1 - 0.028 14.3 0.4 0.29 11.0 0.0 2.8 3 0 0 3 3 3 0 Penicillin-Binding Protein C-terminus Family Peptidase_M20 PF01546.23 KEY69464.1 - 2.2e-21 76.2 0.0 5.6e-21 74.9 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 KEY69464.1 - 3.8e-18 64.6 3.8 0.0012 18.6 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat M20_dimer PF07687.9 KEY69464.1 - 4.8e-05 23.0 0.0 9.2e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KEY69464.1 - 0.0079 15.9 0.0 0.033 13.9 0.0 2.1 3 0 0 3 3 3 1 Peptidase family M28 Peptidase_M42 PF05343.9 KEY69464.1 - 0.013 14.2 0.0 0.028 13.1 0.0 1.5 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Pec_lyase_C PF00544.14 KEY69465.1 - 9.7e-42 142.7 4.1 1.4e-41 142.1 2.9 1.2 1 0 0 1 1 1 1 Pectate lyase Methyltransf_2 PF00891.13 KEY69468.1 - 3.2e-33 114.9 0.1 4.2e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KEY69468.1 - 7.9e-05 23.2 0.0 0.00022 21.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Zn_clus PF00172.13 KEY69470.1 - 3.4e-09 36.4 7.7 5.4e-09 35.8 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEY69470.1 - 3.2e-07 29.3 0.2 5.4e-07 28.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Hira PF07569.6 KEY69471.1 - 1.2e-83 279.7 0.0 2.7e-83 278.4 0.0 1.7 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 KEY69471.1 - 1.1e-44 148.8 18.0 3.2e-07 29.9 0.1 8.7 8 0 0 8 8 8 8 WD domain, G-beta repeat HIRA_B PF09453.5 KEY69471.1 - 1.9e-08 33.5 0.6 1.9e-08 33.5 0.4 2.2 2 0 0 2 2 2 1 HIRA B motif PD40 PF07676.7 KEY69471.1 - 0.00039 19.9 0.4 34 4.2 0.0 4.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat IKI3 PF04762.7 KEY69471.1 - 0.032 12.0 0.4 0.2 9.4 0.0 2.3 2 1 0 3 3 3 0 IKI3 family WD40 PF00400.27 KEY69472.1 - 1.5e-54 179.9 15.2 3.9e-09 36.0 0.0 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 KEY69472.1 - 1.1e-10 41.1 0.1 2.4e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEY69472.1 - 7.2e-10 38.2 0.0 1.8e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 KEY69472.1 - 0.0044 16.5 1.8 5.2 6.4 0.0 3.2 2 1 0 2 2 2 2 PQQ-like domain PRANC PF09372.5 KEY69472.1 - 0.25 11.3 0.0 0.46 10.4 0.0 1.4 1 0 0 1 1 1 0 PRANC domain UMPH-1 PF05822.7 KEY69472.1 - 0.35 10.1 0.0 0.58 9.4 0.0 1.2 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) Mucin PF01456.12 KEY69473.1 - 1.3e-05 25.0 13.2 1.3e-05 25.0 9.1 2.4 2 0 0 2 2 2 1 Mucin-like glycoprotein PAN_4 PF14295.1 KEY69473.1 - 0.0011 18.5 2.0 0.002 17.7 1.4 1.4 1 0 0 1 1 1 1 PAN domain DUF2367 PF10164.4 KEY69473.1 - 6.7 6.6 7.0 43 4.0 0.1 2.5 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) DUF1423 PF07227.6 KEY69473.1 - 8.4 4.9 10.2 12 4.4 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) RNase_H2-Ydr279 PF09468.5 KEY69473.1 - 9.9 5.2 7.4 15 4.6 5.1 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Peptidase_S28 PF05577.7 KEY69476.1 - 1.7e-45 155.3 0.0 1.8e-37 128.9 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 KEY69476.1 - 0.01 15.7 3.3 0.014 15.3 0.1 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF1242 PF06842.7 KEY69477.1 - 5.8e-16 57.6 0.1 7.6e-16 57.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Glyco_hydro_61 PF03443.9 KEY69478.1 - 1.2e-79 267.1 0.0 1.8e-79 266.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Med3 PF11593.3 KEY69478.1 - 1.8 7.7 20.1 2.4 7.2 13.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2265 PF10023.4 KEY69479.1 - 0.1 11.7 0.1 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) 2-Hacid_dh_C PF02826.14 KEY69480.1 - 2.7e-38 130.9 0.0 4.1e-26 91.2 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KEY69480.1 - 0.0029 17.0 0.0 0.0035 16.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain HET PF06985.6 KEY69481.1 - 2.1e-32 112.1 0.0 3.6e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SpoIIE PF07228.7 KEY69481.1 - 0.11 12.2 0.1 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Asparaginase_2 PF01112.13 KEY69482.1 - 7e-82 274.6 6.4 8.2e-82 274.4 4.4 1.0 1 0 0 1 1 1 1 Asparaginase Dicty_REP PF05086.7 KEY69483.1 - 0.093 10.4 6.0 0.15 9.8 4.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein WD40 PF00400.27 KEY69484.1 - 4.4e-08 32.7 1.8 0.0025 17.6 0.0 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat RasGAP PF00616.14 KEY69485.1 - 2.2e-42 144.9 0.0 5.2e-42 143.7 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 KEY69485.1 - 0.00037 20.4 0.0 0.00097 19.0 0.0 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain XRN_N PF03159.13 KEY69486.1 - 1.2e-107 358.6 0.0 2.2e-107 357.8 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Uso1_p115_head PF04869.9 KEY69487.1 - 7.3e-106 353.4 0.0 1.5e-105 352.3 0.0 1.6 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 KEY69487.1 - 5.2e-12 45.8 25.6 5.2e-12 45.8 17.8 4.3 2 1 2 4 4 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region PrmA PF06325.8 KEY69487.1 - 6.3e-10 38.6 0.2 6.3e-10 38.6 0.2 2.4 2 1 0 2 2 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KEY69487.1 - 1.2e-08 35.5 0.1 1e-07 32.5 0.0 2.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY69487.1 - 2.8e-08 34.1 0.0 1.5e-07 31.8 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY69487.1 - 5.8e-08 32.4 0.4 1.7e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY69487.1 - 3.9e-07 30.0 0.9 1.8e-06 27.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Myosin_tail_1 PF01576.14 KEY69487.1 - 6.7e-07 27.4 30.0 6.7e-07 27.4 20.8 3.0 2 1 1 3 3 3 2 Myosin tail Methyltransf_23 PF13489.1 KEY69487.1 - 8.6e-06 25.5 0.0 2.2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY69487.1 - 8.8e-06 25.1 0.4 3e-05 23.4 0.2 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KEY69487.1 - 0.00012 22.4 0.0 0.00042 20.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY69487.1 - 0.0038 17.6 0.0 0.017 15.6 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KEY69487.1 - 0.0063 16.0 0.1 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 KEY69487.1 - 0.016 14.6 0.0 0.04 13.3 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_9 PF08003.6 KEY69487.1 - 0.032 12.9 0.0 0.032 12.9 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1698) TehB PF03848.9 KEY69487.1 - 0.037 13.1 0.0 0.083 12.0 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Cast PF10174.4 KEY69487.1 - 0.96 7.4 67.6 0.028 12.5 42.4 1.5 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone Filament PF00038.16 KEY69487.1 - 2.6 7.4 60.8 58 2.9 38.8 4.0 2 1 0 2 2 2 0 Intermediate filament protein OPT PF03169.10 KEY69488.1 - 1.8e-154 515.5 14.6 2.2e-154 515.3 10.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4212 PF13937.1 KEY69488.1 - 2.2 8.3 10.3 2.8 8.0 0.2 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4212) Rav1p_C PF12234.3 KEY69489.1 - 4.8e-256 850.9 0.0 6.8e-255 847.1 0.0 2.0 1 1 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 KEY69489.1 - 0.0046 16.7 2.8 0.27 11.1 0.0 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat Cmc1 PF08583.5 KEY69490.1 - 0.04 13.6 2.6 0.043 13.6 0.7 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3581 PF12119.3 KEY69490.1 - 0.092 11.9 0.3 0.15 11.2 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3581) CHCH PF06747.8 KEY69490.1 - 0.15 12.0 4.7 2.4 8.1 2.9 2.2 1 1 1 2 2 2 0 CHCH domain tRNA-synt_1 PF00133.17 KEY69491.1 - 1.2e-222 740.2 0.0 1.8e-222 739.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KEY69491.1 - 9.1e-27 93.6 0.0 6.4e-26 90.9 0.0 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KEY69491.1 - 4.5e-20 71.6 0.1 1.1e-09 37.4 0.1 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KEY69491.1 - 0.0099 15.0 0.0 0.075 12.1 0.0 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Mo25 PF08569.6 KEY69492.1 - 3.9e-125 417.3 0.0 4.4e-125 417.1 0.0 1.0 1 0 0 1 1 1 1 Mo25-like RepA_N PF06970.6 KEY69492.1 - 0.045 13.5 0.2 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus SWIB PF02201.13 KEY69493.1 - 3.3e-12 45.8 0.0 6.1e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Pkinase PF00069.20 KEY69494.1 - 8.2e-69 231.6 0.0 1.1e-68 231.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY69494.1 - 1.1e-34 119.7 0.0 6.1e-34 117.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY69494.1 - 8.9e-06 24.8 0.1 0.00043 19.3 0.0 2.6 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 KEY69494.1 - 0.00025 20.1 0.0 0.00042 19.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEY69494.1 - 0.0033 17.1 0.1 0.0078 15.9 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family APC_CDC26 PF10471.4 KEY69495.1 - 0.16 12.6 0.3 0.16 12.6 0.2 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 SNARE PF05739.14 KEY69497.1 - 3.1e-12 45.9 3.0 3.1e-12 45.9 2.1 1.7 2 0 0 2 2 2 1 SNARE domain HXXSHH PF07586.6 KEY69497.1 - 0.015 14.1 1.7 0.025 13.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) Phage_GP20 PF06810.6 KEY69497.1 - 0.025 14.0 1.0 0.14 11.5 0.3 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 Fusion_gly PF00523.13 KEY69497.1 - 0.12 10.4 0.3 0.18 9.8 0.0 1.4 2 0 0 2 2 2 0 Fusion glycoprotein F0 WD40 PF00400.27 KEY69498.1 - 3.8e-10 39.2 6.7 3e-06 26.8 0.0 5.1 6 0 0 6 6 6 2 WD domain, G-beta repeat Glyco_hydro_18 PF00704.23 KEY69499.1 - 3.2e-98 329.3 3.9 3.7e-98 329.1 2.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PPTA PF01239.17 KEY69500.1 - 1.1e-30 103.6 15.7 4.3e-08 32.1 0.3 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF4603 PF15376.1 KEY69500.1 - 1.1 6.3 4.4 1.6 5.8 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) His_Phos_2 PF00328.17 KEY69501.1 - 0.00064 19.1 0.0 0.00095 18.5 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) IER PF05760.7 KEY69501.1 - 0.22 11.4 1.5 0.32 10.8 1.1 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) TALPID3 PF15324.1 KEY69501.1 - 7.2 3.8 5.4 9.7 3.3 3.7 1.0 1 0 0 1 1 1 0 Hedgehog signalling target JmjC PF02373.17 KEY69502.1 - 1.3e-09 38.3 0.1 3.6e-09 36.8 0.1 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 KEY69502.1 - 4.3e-07 30.0 7.8 4.3e-07 30.0 5.4 2.9 3 0 0 3 3 3 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Ribosomal_L5 PF00281.14 KEY69502.1 - 0.0045 16.7 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L5 Cupin_2 PF07883.6 KEY69502.1 - 0.061 12.8 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Cupin domain UbiA PF01040.13 KEY69503.1 - 2e-33 115.7 23.4 2.8e-33 115.2 16.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ribosom_S12_S23 PF00164.20 KEY69504.1 - 9.7e-41 138.0 0.6 1.1e-40 137.8 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Sporozoite_P67 PF05642.6 KEY69505.1 - 0.77 7.5 6.7 1.4 6.7 4.3 1.5 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Inhibitor_I9 PF05922.11 KEY69506.1 - 0.0094 16.4 0.0 0.016 15.7 0.0 1.3 1 1 0 1 1 1 1 Peptidase inhibitor I9 HOOK PF05622.7 KEY69507.1 - 0.00038 18.4 0.4 0.005 14.7 0.2 4.2 3 1 0 4 4 4 3 HOOK protein Alliinase_C PF04864.8 KEY69507.1 - 0.0018 17.0 0.0 0.0032 16.1 0.0 1.3 1 0 0 1 1 1 1 Allinase CH PF00307.26 KEY69507.1 - 0.03 14.3 0.0 0.15 12.1 0.0 2.2 1 0 0 1 1 1 0 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KEY69507.1 - 0.068 12.8 0.0 0.26 10.9 0.0 2.0 1 0 0 1 1 1 0 CAMSAP CH domain ADK PF00406.17 KEY69508.1 - 1.4e-58 197.0 0.0 1.9e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KEY69508.1 - 5.4e-14 51.5 0.0 1.8e-13 49.9 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.1 KEY69508.1 - 8.4e-07 29.8 0.0 1.6e-06 28.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEY69508.1 - 0.00029 20.7 0.0 0.00057 19.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEY69508.1 - 0.0086 15.1 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KEY69508.1 - 0.015 15.5 0.0 0.04 14.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF2802 PF10975.3 KEY69508.1 - 0.017 14.8 0.0 0.056 13.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) DUF4200 PF13863.1 KEY69508.1 - 0.044 13.7 0.1 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Cep57_MT_bd PF06657.8 KEY69508.1 - 0.11 12.5 0.2 0.79 9.7 0.0 2.4 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DASH_Dam1 PF08653.5 KEY69508.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 DASH complex subunit Dam1 MitMem_reg PF13012.1 KEY69509.1 - 4.3e-38 129.9 0.0 1.1e-37 128.6 0.0 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KEY69509.1 - 4.7e-28 97.2 0.4 9.7e-28 96.2 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF809 PF05663.6 KEY69509.1 - 0.34 10.8 3.5 0.71 9.8 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF809) SWIM PF04434.12 KEY69510.1 - 0.01 15.3 7.2 0.087 12.3 0.0 2.8 3 0 0 3 3 3 0 SWIM zinc finger Coprogen_oxidas PF01218.13 KEY69511.1 - 1.1e-133 444.3 0.1 1.3e-133 444.1 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Atg8 PF02991.11 KEY69512.1 - 2.3e-51 172.0 0.2 2.7e-51 171.8 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KEY69512.1 - 3.4e-06 27.1 0.0 4.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Methyltransf_23 PF13489.1 KEY69513.1 - 5.6e-20 71.6 0.0 8.4e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY69513.1 - 4.3e-19 68.8 0.0 9.4e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KEY69513.1 - 8.3e-17 61.1 0.0 2.8e-14 52.8 0.0 2.2 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 KEY69513.1 - 1.3e-16 60.5 0.0 6.2e-16 58.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY69513.1 - 8.7e-15 55.0 0.1 1.1e-13 51.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY69513.1 - 4.1e-14 53.1 0.0 8.4e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY69513.1 - 6.5e-10 39.2 0.0 1.3e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY69513.1 - 8.8e-08 32.1 0.0 2.1e-07 31.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY69513.1 - 1.6e-07 30.6 0.0 2.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.7 KEY69513.1 - 1.4e-05 24.5 0.0 4.4e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase MTS PF05175.9 KEY69513.1 - 1.5e-05 24.4 0.1 0.0023 17.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain MetW PF07021.7 KEY69513.1 - 0.00084 18.7 0.1 0.047 13.0 0.0 2.8 2 1 1 3 3 3 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 KEY69513.1 - 0.019 15.7 0.0 0.04 14.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.6 KEY69513.1 - 0.021 14.3 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.14 KEY69513.1 - 0.03 13.8 0.0 0.052 13.0 0.0 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 KEY69513.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 KEY69513.1 - 0.1 11.7 0.0 0.5 9.5 0.0 1.9 1 1 0 1 1 1 0 O-methyltransferase DOT1 PF08123.8 KEY69513.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_15 PF09445.5 KEY69513.1 - 0.11 12.0 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase SAMP PF05924.6 KEY69514.1 - 0.015 14.4 0.8 0.044 12.9 0.6 1.8 1 0 0 1 1 1 0 SAMP Motif TMEM52 PF14979.1 KEY69514.1 - 0.32 10.8 2.9 1.6 8.6 0.5 2.6 3 0 0 3 3 3 0 Transmembrane 52 Trp_syntA PF00290.15 KEY69515.1 - 2.1e-93 311.6 0.0 3.5e-93 310.8 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 KEY69515.1 - 7.5e-45 153.4 1.0 1.3e-44 152.6 0.7 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ribosomal_L28 PF00830.14 KEY69516.1 - 3.2e-11 42.8 0.8 5e-11 42.2 0.5 1.3 1 0 0 1 1 1 1 Ribosomal L28 family HAUS4 PF14735.1 KEY69517.1 - 0.067 12.4 0.1 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 Aminotran_1_2 PF00155.16 KEY69518.1 - 1.5e-91 307.0 0.0 1.7e-91 306.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Sugar_tr PF00083.19 KEY69519.1 - 1.3e-72 244.8 21.6 1.6e-72 244.5 15.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY69519.1 - 9.2e-15 54.2 32.0 2.8e-12 46.0 4.8 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily HhH-GPD PF00730.20 KEY69519.1 - 0.00011 22.4 0.0 0.00023 21.4 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein adh_short PF00106.20 KEY69521.1 - 1e-17 64.5 0.8 2.6e-17 63.2 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY69521.1 - 1.7e-07 31.0 0.0 4.1e-07 29.8 0.0 1.6 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 KEY69521.1 - 7.2e-05 22.3 0.0 0.00016 21.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KEY69521.1 - 0.00028 20.7 0.0 0.0004 20.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.7 KEY69521.1 - 0.0029 16.5 0.0 0.0076 15.2 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KEY69521.1 - 0.0067 16.4 0.4 0.067 13.1 0.3 2.3 1 1 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 KEY69521.1 - 0.013 15.6 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 KEY69521.1 - 0.098 12.0 0.3 0.19 11.1 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HTH_8 PF02954.14 KEY69522.1 - 0.048 13.1 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Sugar_tr PF00083.19 KEY69524.1 - 2.7e-106 355.8 22.6 3.5e-84 282.9 9.6 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KEY69524.1 - 2.2e-21 75.9 35.0 4.3e-21 75.0 19.5 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEY69524.1 - 0.00057 18.3 2.9 0.00057 18.3 2.0 3.3 3 1 0 3 3 3 2 MFS/sugar transport protein DUF1992 PF09350.5 KEY69525.1 - 1.4e-24 85.6 0.3 3.4e-24 84.4 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) MFS_1 PF07690.11 KEY69526.1 - 7.1e-23 80.8 31.5 7.1e-23 80.8 21.8 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY69526.1 - 1.3e-12 47.0 27.2 2.3e-12 46.2 18.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter LacAB_rpiB PF02502.13 KEY69526.1 - 0.0059 16.2 0.4 0.013 15.1 0.3 1.5 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Entericidin PF08085.6 KEY69526.1 - 0.045 13.5 0.6 0.12 12.1 0.4 1.8 1 0 0 1 1 1 0 Entericidin EcnA/B family DUF2583 PF10762.4 KEY69526.1 - 0.07 13.2 0.8 0.24 11.5 0.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) WD40 PF00400.27 KEY69527.1 - 1e-76 250.2 20.5 3.5e-11 42.5 0.7 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KEY69527.1 - 4.5e-06 25.0 1.6 0.007 14.5 0.0 3.9 2 2 2 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KEY69527.1 - 0.0016 17.2 0.2 2.4 6.7 0.1 3.5 1 1 3 4 4 4 2 Nup133 N terminal like DUF1040 PF06288.8 KEY69528.1 - 0.017 15.3 1.8 0.036 14.3 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1040) DUF2183 PF09949.4 KEY69529.1 - 3.3e-26 91.1 0.0 7e-26 90.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DUF2638 PF10937.3 KEY69530.1 - 7.7e-36 123.5 2.7 2.1e-35 122.1 1.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2638) AA_permease PF00324.16 KEY69531.1 - 2.6e-139 464.6 42.6 3e-139 464.4 29.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEY69531.1 - 1.9e-35 122.2 44.4 2.5e-35 121.8 30.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1741 PF08427.5 KEY69532.1 - 1.8e-87 292.7 0.0 3e-87 292.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) RasGEF PF00617.14 KEY69534.1 - 1.1e-55 188.3 0.1 1.9e-55 187.5 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KEY69534.1 - 5.5e-19 68.2 0.0 1.5e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 KEY69534.1 - 2.2e-05 23.9 0.0 4.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KEY69534.1 - 0.00011 21.5 0.0 0.00036 19.8 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KEY69534.1 - 0.012 15.1 0.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 0 Variant SH3 domain MFS_1 PF07690.11 KEY69535.1 - 3.4e-16 58.9 30.8 3.4e-16 58.9 21.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KEY69535.1 - 3.8e-09 36.2 6.8 6.7e-09 35.4 3.5 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Imm38 PF15599.1 KEY69535.1 - 0.0052 16.3 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Immunity protein 38 ATP-grasp_2 PF08442.5 KEY69536.1 - 1.2e-76 256.5 0.3 2.2e-76 255.7 0.2 1.4 1 0 0 1 1 1 1 ATP-grasp domain DNA_binding_1 PF01035.15 KEY69536.1 - 5.6e-27 93.3 0.1 2.6e-26 91.1 0.0 2.1 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Ligase_CoA PF00549.14 KEY69536.1 - 1.6e-26 92.7 0.4 2.8e-26 91.9 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase Fe-S_biosyn PF01521.15 KEY69536.1 - 3.9e-15 55.7 0.0 1.2e-14 54.1 0.0 1.8 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis ATP-grasp_5 PF13549.1 KEY69536.1 - 3.3e-07 29.7 0.1 5.6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 KEY69536.1 - 0.0012 18.4 1.0 0.032 13.8 0.1 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peripla_BP_2 PF01497.13 KEY69536.1 - 0.052 12.6 0.2 0.1 11.7 0.1 1.4 1 0 0 1 1 1 0 Periplasmic binding protein ATP-grasp_4 PF13535.1 KEY69536.1 - 0.073 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain DUF3391 PF11871.3 KEY69536.1 - 0.096 12.8 0.7 2.7 8.2 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Ank_2 PF12796.2 KEY69537.1 - 3.4e-46 155.4 0.0 7.9e-15 54.9 0.0 5.7 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 KEY69537.1 - 2.1e-32 109.3 0.0 1.4e-05 24.6 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 KEY69537.1 - 2.1e-32 110.8 0.0 3.7e-11 43.2 0.0 6.5 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY69537.1 - 1.1e-30 102.6 0.0 0.00013 21.8 0.0 8.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 KEY69537.1 - 9.1e-26 89.3 0.0 2.4e-06 27.5 0.0 7.3 2 2 5 7 7 7 5 Ankyrin repeats (many copies) HET PF06985.6 KEY69537.1 - 3.8e-21 75.6 6.5 9.4e-20 71.1 4.5 2.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 KEY69537.1 - 2.8e-05 23.8 0.0 8.8e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KEY69537.1 - 0.00072 19.7 0.0 0.0019 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KEY69537.1 - 0.051 13.7 0.1 0.19 11.9 0.1 2.0 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.9 KEY69537.1 - 0.21 10.5 1.8 1 8.2 0.0 2.3 1 1 0 2 2 2 0 KAP family P-loop domain Fructosamin_kin PF03881.9 KEY69538.1 - 3.4e-74 249.3 0.0 3.7e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KEY69538.1 - 3.9e-05 23.4 0.0 6.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Snf7 PF03357.16 KEY69539.1 - 8.1e-36 122.9 10.8 1e-35 122.6 7.5 1.1 1 0 0 1 1 1 1 Snf7 DUF2520 PF10728.4 KEY69539.1 - 0.01 15.3 0.1 0.025 14.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2520) PMSR PF01625.16 KEY69539.1 - 0.16 11.8 2.1 12 5.7 0.1 2.3 1 1 1 2 2 2 0 Peptide methionine sulfoxide reductase DUF1843 PF08898.5 KEY69539.1 - 0.42 10.6 4.5 9.2 6.3 0.4 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) NPV_P10 PF05531.7 KEY69539.1 - 0.55 10.5 6.2 9.4 6.5 0.0 3.6 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein AAA PF00004.24 KEY69540.1 - 7.4e-62 207.3 0.0 4.6e-45 153.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEY69540.1 - 1.2e-08 35.1 0.3 6.5e-05 22.9 0.0 3.3 3 1 0 3 3 2 2 AAA ATPase domain AAA_5 PF07728.9 KEY69540.1 - 1.6e-07 31.1 0.0 0.00018 21.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KEY69540.1 - 1.3e-06 27.6 0.0 0.001 18.1 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KEY69540.1 - 4.8e-06 26.7 0.0 0.0063 16.6 0.0 3.9 3 1 0 3 3 2 1 AAA domain AAA_33 PF13671.1 KEY69540.1 - 6e-06 26.1 0.0 0.005 16.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KEY69540.1 - 6.1e-06 26.1 0.0 0.00063 19.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KEY69540.1 - 2.3e-05 24.0 0.0 0.01 15.5 0.0 3.3 3 1 0 3 3 3 1 Part of AAA domain Zeta_toxin PF06414.7 KEY69540.1 - 5.9e-05 22.2 0.0 0.0018 17.4 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_2 PF07724.9 KEY69540.1 - 8.8e-05 22.4 0.0 0.00047 20.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 KEY69540.1 - 0.00017 21.0 0.0 0.015 14.7 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.1 KEY69540.1 - 0.00031 20.2 0.7 1 8.7 0.1 3.4 2 2 0 3 3 3 2 AAA domain Sigma54_activ_2 PF14532.1 KEY69540.1 - 0.00031 20.8 0.0 0.035 14.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 KEY69540.1 - 0.00054 20.2 0.1 1.7 8.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain TIP49 PF06068.8 KEY69540.1 - 0.00072 18.3 0.1 0.17 10.5 0.0 2.5 3 0 0 3 3 3 1 TIP49 C-terminus AAA_17 PF13207.1 KEY69540.1 - 0.00084 20.1 0.0 0.87 10.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KEY69540.1 - 0.00091 19.3 0.0 0.038 14.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Sigma54_activat PF00158.21 KEY69540.1 - 0.003 17.0 0.2 0.24 10.8 0.0 3.2 3 1 0 3 3 3 1 Sigma-54 interaction domain DUF815 PF05673.8 KEY69540.1 - 0.0055 15.6 0.0 1.6 7.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.7 KEY69540.1 - 0.008 15.8 0.1 1.3 8.6 0.0 3.1 3 0 0 3 3 3 1 NACHT domain Mg_chelatase PF01078.16 KEY69540.1 - 0.0083 15.3 0.2 0.12 11.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.10 KEY69540.1 - 0.019 14.8 0.1 0.13 12.0 0.0 2.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 KEY69540.1 - 0.027 14.7 0.2 1.3 9.3 0.0 3.0 3 1 0 3 3 3 0 ABC transporter UPF0079 PF02367.12 KEY69540.1 - 0.034 13.7 0.0 1.9 8.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 KEY69540.1 - 0.053 13.0 0.0 2.3 7.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.1 KEY69540.1 - 0.055 13.4 0.0 0.82 9.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 KEY69540.1 - 0.12 11.8 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Cytochrom_C PF00034.16 KEY69541.1 - 2.8e-11 44.0 0.1 4.4e-11 43.4 0.1 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KEY69541.1 - 7e-10 38.9 2.3 3.3e-09 36.7 1.6 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KEY69541.1 - 0.008 15.6 0.8 0.027 13.9 0.1 2.0 2 1 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.9 KEY69541.1 - 0.098 12.9 0.0 0.16 12.2 0.0 1.4 1 1 0 1 1 1 0 Di-haem cytochrome c peroxidase RNase_PH PF01138.16 KEY69543.1 - 2.2e-15 57.1 0.0 3.9e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KEY69543.1 - 0.076 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 ATE_C PF04377.10 KEY69544.1 - 5.8e-43 145.9 0.2 1e-42 145.1 0.2 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 KEY69544.1 - 4.9e-16 58.3 0.3 1.2e-15 57.0 0.2 1.7 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.1 KEY69544.1 - 0.0029 17.5 0.3 0.013 15.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain NUDIX PF00293.23 KEY69545.1 - 4.2e-20 71.7 0.2 5.1e-20 71.4 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.1 KEY69545.1 - 0.029 13.6 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase NEMO PF11577.3 KEY69545.1 - 0.12 12.0 2.4 1.5 8.6 0.4 2.4 1 1 1 2 2 2 0 NF-kappa-B essential modulator NEMO LSM PF01423.17 KEY69546.1 - 4.2e-11 42.2 0.0 7.7e-11 41.3 0.0 1.4 1 0 0 1 1 1 1 LSM domain Ras PF00071.17 KEY69548.1 - 1.6e-64 216.1 0.5 1.9e-64 215.9 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEY69548.1 - 9.8e-22 77.6 0.0 1.5e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEY69548.1 - 2.8e-16 59.2 0.1 3.5e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEY69548.1 - 1.7e-05 24.0 0.1 2.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KEY69548.1 - 2.4e-05 23.8 0.1 4.5e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEY69548.1 - 4.9e-05 23.2 0.1 0.0001 22.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 KEY69548.1 - 0.00013 22.1 0.1 0.027 14.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 KEY69548.1 - 0.00027 20.1 0.0 0.00039 19.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KEY69548.1 - 0.00052 19.3 0.1 0.0063 15.8 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 KEY69548.1 - 0.00084 19.4 0.0 0.0015 18.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KEY69548.1 - 0.0027 16.8 0.1 0.0081 15.3 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 KEY69548.1 - 0.019 14.8 0.2 0.056 13.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KEY69548.1 - 0.02 14.8 0.1 0.1 12.5 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 KEY69548.1 - 0.037 13.7 0.1 0.071 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 KEY69548.1 - 0.051 13.1 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 KEY69548.1 - 0.066 12.2 0.0 0.21 10.5 0.0 1.7 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 KEY69548.1 - 0.086 12.3 0.1 0.37 10.2 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 KEY69548.1 - 0.087 13.1 0.1 0.14 12.4 0.0 1.6 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.15 KEY69548.1 - 1.3 7.6 4.2 11 4.5 0.3 2.6 1 1 1 2 2 2 0 G-protein alpha subunit WD40 PF00400.27 KEY69551.1 - 6.4e-22 76.5 9.4 6.9e-05 22.5 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_2 PF13360.1 KEY69551.1 - 1.2e-06 28.1 0.4 0.0063 16.0 0.0 3.1 2 1 1 3 3 3 3 PQQ-like domain Nup160 PF11715.3 KEY69551.1 - 1.3e-05 23.5 0.3 0.0075 14.4 0.0 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_3 PF13570.1 KEY69551.1 - 0.0012 19.0 0.0 0.33 11.2 0.0 4.1 4 0 0 4 4 4 1 PQQ-like domain DUF627 PF04781.7 KEY69551.1 - 0.051 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Sigma70_r1_2 PF00140.15 KEY69551.1 - 0.1 12.2 0.5 0.23 11.1 0.3 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 HAD PF12710.2 KEY69551.1 - 0.11 12.6 0.0 3.7 7.6 0.0 2.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 KEY69552.1 - 9.7e-21 72.8 7.3 3.1e-06 26.8 0.0 7.9 8 0 0 8 8 8 4 WD domain, G-beta repeat DUF3639 PF12341.3 KEY69552.1 - 4.8e-11 42.4 3.1 2.4e-10 40.2 1.9 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 KEY69552.1 - 1.5e-07 30.5 0.0 2.9e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Coatomer WD associated region eIF2A PF08662.6 KEY69552.1 - 0.00033 20.4 0.2 0.0037 16.9 0.2 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A DNA_pol_alpha_N PF12254.3 KEY69552.1 - 0.004 16.9 3.0 0.004 16.9 2.1 2.1 2 0 0 2 2 1 1 DNA polymerase alpha subunit p180 N terminal Nucleoplasmin PF03066.10 KEY69552.1 - 0.0079 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Nucleoplasmin KTSC PF13619.1 KEY69552.1 - 0.019 14.5 0.0 4.5 6.9 0.0 2.8 2 0 0 2 2 2 0 KTSC domain RXT2_N PF08595.6 KEY69552.1 - 0.03 14.1 1.4 0.055 13.2 1.0 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal MMS1_N PF10433.4 KEY69552.1 - 0.04 12.0 0.0 0.1 10.7 0.0 1.6 1 1 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term IKI3 PF04762.7 KEY69552.1 - 0.042 11.6 0.2 0.086 10.6 0.1 1.4 1 1 0 1 1 1 0 IKI3 family Gp5_C PF06715.7 KEY69552.1 - 0.11 12.4 0.4 0.45 10.5 0.2 2.0 1 0 0 1 1 1 0 Gp5 C-terminal repeat (3 copies) PBP1_TM PF14812.1 KEY69552.1 - 4.6 7.6 10.6 1 9.7 4.3 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-CCCH_2 PF14608.1 KEY69553.1 - 3.1 7.9 5.7 0.27 11.3 0.4 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type PP-binding PF00550.20 KEY69554.1 - 2e-11 44.0 0.1 2.7e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 KEY69554.1 - 2.7e-06 27.3 0.1 3.4e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier Peptidase_M14 PF00246.19 KEY69555.1 - 3.7e-39 135.0 0.7 6.8e-39 134.1 0.5 1.4 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 KEY69555.1 - 0.011 14.6 0.0 4.3 6.1 0.0 3.2 3 0 0 3 3 3 0 Succinylglutamate desuccinylase / Aspartoacylase family Fer4 PF00037.22 KEY69556.1 - 1.3e-13 49.9 16.5 5e-08 32.2 2.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 KEY69556.1 - 6.5e-12 45.6 10.6 1e-11 44.9 7.3 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 KEY69556.1 - 2.6e-10 40.4 7.4 5.1e-10 39.4 5.1 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 KEY69556.1 - 7.1e-10 39.4 6.9 0.00019 22.0 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 KEY69556.1 - 1.7e-09 37.3 22.0 6.6e-08 32.2 8.4 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 KEY69556.1 - 6.2e-09 35.5 32.3 1e-05 25.3 8.7 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 KEY69556.1 - 1.2e-07 31.2 14.7 0.00041 20.1 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 KEY69556.1 - 1.2e-07 31.6 20.8 2.5e-05 24.1 8.2 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 KEY69556.1 - 1.9e-07 30.6 17.1 0.0011 18.6 3.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 KEY69556.1 - 4.6e-06 26.5 12.7 0.00054 20.0 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 KEY69556.1 - 5.9e-06 26.5 9.7 0.00077 19.7 7.7 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 KEY69556.1 - 3.3e-05 24.2 9.4 0.012 16.0 0.5 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 KEY69556.1 - 0.0088 16.4 15.4 0.28 11.5 3.2 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 KEY69556.1 - 0.012 16.1 13.1 0.2 12.2 1.1 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 KEY69556.1 - 0.063 13.8 16.9 0.15 12.7 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 KEY69556.1 - 0.1 12.7 4.8 0.24 11.5 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain F-box-like PF12937.2 KEY69558.1 - 0.00098 18.8 0.0 0.00098 18.8 0.0 3.6 5 0 0 5 5 5 1 F-box-like F-box PF00646.28 KEY69558.1 - 0.0013 18.2 1.7 0.0019 17.7 0.0 2.3 2 0 0 2 2 2 1 F-box domain EHN PF06441.7 KEY69559.1 - 3.2e-33 113.9 0.1 6.9e-32 109.7 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KEY69559.1 - 5.3e-13 49.3 0.6 1e-12 48.4 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY69559.1 - 2.4e-06 27.3 0.0 3.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PLRV_ORF5 PF01690.12 KEY69560.1 - 8.5 5.4 7.7 7.5 5.5 4.6 1.4 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein Sugar_tr PF00083.19 KEY69561.1 - 1.1e-75 254.9 16.9 1.3e-75 254.7 11.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY69561.1 - 1e-33 116.5 31.2 7.1e-31 107.2 14.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MIG-14_Wnt-bd PF06664.7 KEY69561.1 - 0.0087 14.9 0.6 0.015 14.1 0.4 1.3 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion FAD_binding_3 PF01494.14 KEY69562.1 - 9.3e-12 44.6 1.9 6.5e-07 28.7 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KEY69562.1 - 4.9e-09 35.5 0.1 0.00027 19.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY69562.1 - 0.0001 22.2 0.2 0.00055 19.9 0.1 2.2 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEY69562.1 - 0.00016 20.6 0.0 0.00026 19.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KEY69562.1 - 0.00023 21.1 0.3 0.0034 17.2 0.3 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY69562.1 - 0.00025 21.3 0.2 0.21 12.0 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEY69562.1 - 0.0011 17.5 0.1 0.26 9.7 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Amino_oxidase PF01593.19 KEY69562.1 - 0.025 13.6 0.0 0.67 8.9 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 KEY69562.1 - 0.056 12.5 0.1 0.29 10.1 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_4 PF01565.18 KEY69563.1 - 2.7e-15 56.0 0.4 4.4e-15 55.3 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY69563.1 - 9.2e-05 22.2 0.8 0.00023 20.9 0.0 2.1 2 0 0 2 2 2 1 Berberine and berberine like DUF4376 PF14301.1 KEY69564.1 - 0.025 14.6 0.1 0.25 11.4 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4376) RhgB_N PF09284.5 KEY69565.1 - 1.9e-78 263.2 1.3 3.1e-78 262.5 0.9 1.3 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 KEY69565.1 - 1.1e-20 73.9 0.0 3.8e-20 72.2 0.0 2.1 2 1 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 KEY69565.1 - 1.5e-14 53.9 4.2 3.2e-14 52.8 2.9 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 KEY69565.1 - 0.086 12.9 8.1 0.26 11.3 1.9 3.4 4 0 0 4 4 4 0 Carboxypeptidase regulatory-like domain DUF2688 PF10892.3 KEY69566.1 - 0.13 11.9 0.8 0.26 11.0 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) p450 PF00067.17 KEY69568.1 - 3.4e-46 157.7 0.0 4.5e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 KEY69569.1 - 1.1e-09 38.4 0.0 1.7e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY69569.1 - 0.00038 20.1 0.0 0.00059 19.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY69569.1 - 0.034 13.5 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KEY69569.1 - 0.041 12.9 0.0 0.077 12.0 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TIR-like PF10137.4 KEY69569.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain NAD_binding_10 PF13460.1 KEY69569.1 - 0.13 12.3 0.1 0.33 10.9 0.0 1.8 1 1 0 1 1 1 0 NADH(P)-binding DUF1929 PF09118.6 KEY69570.1 - 1.1e-22 79.9 0.0 2.4e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.1 KEY69570.1 - 5.3e-12 45.3 6.7 0.0002 21.4 0.0 5.3 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.20 KEY69570.1 - 6.8e-11 41.5 0.1 0.00053 19.4 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 KEY69570.1 - 3e-07 30.0 9.7 0.016 14.9 0.1 5.9 4 2 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KEY69570.1 - 3.4e-07 29.7 1.0 0.08 12.7 0.0 5.2 5 0 0 5 5 5 2 Kelch motif PAN_1 PF00024.21 KEY69570.1 - 7.7e-06 25.5 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 PAN domain Glyoxal_oxid_N PF07250.6 KEY69570.1 - 7.5e-05 21.9 0.0 0.23 10.4 0.0 2.7 2 2 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_3 PF13415.1 KEY69570.1 - 7.5e-05 22.7 1.7 0.0055 16.8 0.0 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain PAN_4 PF14295.1 KEY69570.1 - 0.0058 16.3 2.2 0.0058 16.3 1.5 2.2 2 0 0 2 2 2 1 PAN domain FAD_binding_4 PF01565.18 KEY69571.1 - 1.2e-18 66.9 3.2 2.3e-18 65.9 2.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY69571.1 - 1.2e-08 34.6 0.0 2.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cu-oxidase_2 PF07731.9 KEY69572.1 - 7.8e-27 93.4 4.1 8.4e-24 83.6 0.5 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KEY69572.1 - 1.5e-23 82.7 0.3 5.4e-23 80.9 0.2 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 KEY69572.1 - 0.00046 20.1 0.1 0.038 13.8 0.0 3.2 3 1 0 3 3 3 1 Multicopper oxidase DUF4470 PF14737.1 KEY69574.1 - 1.7e-21 75.7 0.1 3.6e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 KEY69574.1 - 3e-09 36.5 12.0 8.1e-09 35.2 8.3 1.8 1 0 0 1 1 1 1 MYND finger Pectinesterase PF01095.14 KEY69575.1 - 1e-48 165.4 6.4 1.2e-48 165.2 4.4 1.0 1 0 0 1 1 1 1 Pectinesterase CFEM PF05730.6 KEY69576.1 - 5e-07 29.4 6.2 8.6e-07 28.7 4.3 1.3 1 0 0 1 1 1 1 CFEM domain DUF3295 PF11702.3 KEY69576.1 - 5.6 5.8 9.4 7.3 5.4 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) CFEM PF05730.6 KEY69577.1 - 2e-10 40.3 7.3 2.9e-10 39.8 5.1 1.3 1 0 0 1 1 1 1 CFEM domain MGC-24 PF05283.6 KEY69577.1 - 0.0013 18.6 6.8 0.0018 18.1 4.7 1.2 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) MSP1_C PF07462.6 KEY69577.1 - 1 7.6 5.5 1.2 7.3 3.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus MFS_1 PF07690.11 KEY69578.1 - 3.9e-12 45.5 57.9 4.3e-10 38.8 40.0 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Caleosin PF05042.8 KEY69579.1 - 1.1e-59 200.8 0.0 1.3e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein FAD_binding_8 PF08022.7 KEY69580.1 - 3.6e-19 68.5 0.0 8.1e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KEY69580.1 - 3.7e-12 46.4 3.6 4.1e-12 46.2 1.0 2.0 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KEY69580.1 - 1.9e-11 44.1 0.0 9.3e-11 41.8 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain EF-hand_7 PF13499.1 KEY69580.1 - 0.00028 20.9 3.7 0.011 15.8 0.1 1.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KEY69580.1 - 0.0029 16.8 0.2 0.01 15.0 0.2 1.9 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 KEY69580.1 - 0.029 13.7 0.1 0.068 12.5 0.1 1.6 1 0 0 1 1 1 0 EF hand FAD_binding_6 PF00970.19 KEY69580.1 - 0.033 14.3 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain EF-hand_6 PF13405.1 KEY69580.1 - 0.052 13.4 0.5 0.19 11.6 0.3 2.0 2 0 0 2 2 2 0 EF-hand domain Glyco_hydro_61 PF03443.9 KEY69581.1 - 1.5e-59 201.4 0.0 1.8e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CHRD PF07452.7 KEY69582.1 - 4.6e-05 24.0 0.0 0.00011 22.7 0.0 1.7 1 1 0 1 1 1 1 CHRD domain Glyco_hydro_7 PF00840.15 KEY69583.1 - 3.1e-174 579.4 12.4 3.7e-174 579.1 8.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Esterase_phd PF10503.4 KEY69584.1 - 7.3e-23 80.9 0.4 1e-22 80.4 0.3 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KEY69584.1 - 1.4e-10 40.8 0.2 2e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEY69584.1 - 1.3e-06 28.2 0.1 1.9e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY69584.1 - 0.00031 20.7 0.6 0.00051 20.0 0.4 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY69584.1 - 0.0045 16.5 0.1 0.0068 15.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KEY69584.1 - 0.038 12.7 0.3 0.053 12.2 0.2 1.1 1 0 0 1 1 1 0 Carboxylesterase family Esterase PF00756.15 KEY69584.1 - 0.066 12.6 0.2 0.092 12.1 0.1 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 KEY69584.1 - 0.2 11.0 0.6 0.52 9.7 0.4 1.8 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Ferric_reduct PF01794.14 KEY69585.1 - 3 7.9 11.2 2.5 8.1 6.3 1.9 1 1 1 2 2 2 0 Ferric reductase like transmembrane component Sugar_tr PF00083.19 KEY69586.1 - 1.8e-76 257.5 16.4 2.1e-76 257.3 11.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY69586.1 - 5.9e-22 77.8 10.4 5.9e-22 77.8 7.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily PUCC PF03209.10 KEY69586.1 - 0.0033 16.2 3.6 0.0033 16.2 2.5 1.7 2 0 0 2 2 2 1 PUCC protein DUF667 PF05018.8 KEY69586.1 - 0.052 12.7 0.2 0.087 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF667) Abhydrolase_6 PF12697.2 KEY69589.1 - 2.2e-32 112.7 0.2 2.6e-32 112.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY69589.1 - 5.4e-21 75.1 0.0 3.9e-20 72.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY69589.1 - 7.4e-16 58.2 0.0 4.8e-15 55.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KEY69589.1 - 5.9e-06 26.1 0.0 8.9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.16 KEY69589.1 - 1e-05 24.8 0.1 0.028 13.6 0.0 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family Ndr PF03096.9 KEY69589.1 - 0.049 12.1 0.0 6.5 5.1 0.0 2.6 3 0 0 3 3 3 0 Ndr family Hydrolase_4 PF12146.3 KEY69589.1 - 0.082 12.7 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase FSH1 PF03959.8 KEY69589.1 - 0.09 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) MFS_1 PF07690.11 KEY69590.1 - 8.1e-39 133.3 35.2 8.1e-39 133.3 24.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY69590.1 - 2.1e-08 33.2 23.6 5e-08 31.9 16.4 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter CbtA PF09490.5 KEY69590.1 - 0.0011 18.3 0.5 0.006 15.9 0.2 2.2 2 0 0 2 2 2 1 Probable cobalt transporter subunit (CbtA) NmrA PF05368.8 KEY69591.1 - 2.4e-55 187.3 0.0 2.9e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY69591.1 - 9.2e-12 45.3 0.0 1.2e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEY69591.1 - 0.0016 17.1 0.0 0.0023 16.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NolV PF06635.7 KEY69591.1 - 0.091 11.9 0.7 0.13 11.3 0.2 1.5 2 0 0 2 2 2 0 Nodulation protein NolV HET PF06985.6 KEY69592.1 - 8.5e-26 90.7 0.2 3.6e-25 88.7 0.0 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) FMN_dh PF01070.13 KEY69593.1 - 1.6e-101 339.7 3.3 7.6e-100 334.2 2.3 2.1 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KEY69593.1 - 1.8e-12 46.9 0.0 9.4e-12 44.5 0.0 2.1 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 KEY69593.1 - 2.5e-06 26.6 0.1 0.00019 20.4 0.1 2.3 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KEY69593.1 - 2.7e-06 26.5 0.2 4.8e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 KEY69593.1 - 0.0039 16.3 1.1 0.59 9.1 0.1 2.5 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 KEY69593.1 - 0.0055 15.7 0.0 0.032 13.1 0.0 2.0 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase NMO PF03060.10 KEY69593.1 - 0.026 13.6 0.3 0.044 12.9 0.2 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.16 KEY69593.1 - 0.026 13.7 0.0 0.19 10.9 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein PcrB PF01884.12 KEY69593.1 - 0.12 11.5 0.0 4.7 6.4 0.0 2.5 2 1 0 2 2 2 0 PcrB family DUF3433 PF11915.3 KEY69594.1 - 4e-29 100.6 14.2 2.1e-20 72.6 2.6 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) FAD_binding_4 PF01565.18 KEY69596.1 - 3.4e-21 75.1 1.5 7.3e-21 74.1 1.0 1.6 1 1 0 1 1 1 1 FAD binding domain Methyltransf_31 PF13847.1 KEY69597.1 - 1e-05 25.2 0.0 0.00056 19.5 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY69597.1 - 1.5e-05 24.8 0.0 3.9e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY69597.1 - 0.071 13.6 0.0 0.66 10.5 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KEY69597.1 - 0.099 13.1 0.0 0.46 11.0 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain adh_short PF00106.20 KEY69598.1 - 1.1e-15 57.9 0.8 7.5e-15 55.2 0.2 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY69598.1 - 1.3e-07 31.5 0.1 1.9e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KEY69598.1 - 0.001 19.0 0.2 0.0044 17.0 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEY69598.1 - 0.0015 18.0 0.0 0.0029 17.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family p450 PF00067.17 KEY69599.1 - 1.1e-35 123.0 0.0 1.5e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 KEY69600.1 - 7.5e-18 64.3 8.7 1.3e-16 60.3 6.0 2.4 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY69600.1 - 0.00063 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 KEY69601.1 - 9e-36 123.3 0.0 2.6e-35 121.8 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 FAD_binding_4 PF01565.18 KEY69603.1 - 4.3e-22 78.0 1.9 6.7e-22 77.4 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY69603.1 - 0.00022 21.0 0.0 0.0005 19.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like PLA2_B PF01735.13 KEY69604.1 - 2.8e-16 58.7 0.1 6e-08 31.3 0.0 2.7 2 1 0 2 2 2 2 Lysophospholipase catalytic domain HET PF06985.6 KEY69605.1 - 6.1e-18 65.3 6.4 1.1e-14 54.7 1.1 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.6 KEY69606.1 - 2.6e-28 98.8 1.0 6.7e-28 97.5 0.1 2.1 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 KEY69607.1 - 6.2e-20 71.7 0.0 8.1e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY69607.1 - 2.6e-15 56.8 0.0 3.3e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY69607.1 - 0.0048 16.5 0.0 0.012 15.2 0.0 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KEY69607.1 - 0.034 13.0 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.5 KEY69607.1 - 0.064 12.3 0.0 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF2284 PF10050.4 KEY69608.1 - 2.1 7.8 34.4 0.13 11.8 0.5 5.3 6 1 1 7 7 7 0 Predicted metal-binding protein (DUF2284) RTA1 PF04479.8 KEY69609.1 - 9e-50 169.2 7.1 9e-50 169.2 4.9 1.6 2 0 0 2 2 2 1 RTA1 like protein Aldedh PF00171.17 KEY69611.1 - 2.3e-143 477.9 0.0 2.7e-143 477.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family peroxidase PF00141.18 KEY69612.1 - 3.5e-90 301.5 0.0 3.1e-46 157.7 0.0 2.3 2 0 0 2 2 2 2 Peroxidase GST_C PF00043.20 KEY69612.1 - 0.04 13.8 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain ICMT PF04140.9 KEY69614.1 - 1.3e-10 41.3 0.0 2.9e-08 33.7 0.0 2.4 2 0 0 2 2 2 2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KEY69614.1 - 8.3e-09 35.5 0.6 2e-07 31.1 0.1 2.4 1 1 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 KEY69614.1 - 0.0016 17.1 0.0 0.0021 16.6 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Ank_2 PF12796.2 KEY69616.1 - 2e-46 156.2 1.5 7.6e-17 61.4 1.6 8.2 5 2 4 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.25 KEY69616.1 - 1.9e-31 106.2 20.9 1.1e-05 24.9 0.1 11.3 11 0 0 11 11 11 6 Ankyrin repeat Ank_3 PF13606.1 KEY69616.1 - 3.7e-30 100.9 12.4 0.0023 18.0 0.0 12.9 13 0 0 13 13 13 7 Ankyrin repeat Ank_4 PF13637.1 KEY69616.1 - 2.7e-24 85.0 10.3 3.4e-07 30.5 0.7 10.1 9 2 1 10 10 10 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY69616.1 - 3.1e-20 71.7 24.7 2.6e-06 27.4 0.2 10.2 7 1 3 10 10 10 6 Ankyrin repeats (many copies) adh_short PF00106.20 KEY69617.1 - 1e-18 67.7 1.9 1.5e-18 67.2 1.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY69617.1 - 1.6e-07 31.1 1.5 1.6e-07 31.1 1.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KEY69617.1 - 1.9e-06 27.8 0.2 3.3e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KEY69617.1 - 0.06 13.3 0.4 0.1 12.5 0.3 1.4 1 0 0 1 1 1 0 NADH(P)-binding E1-E2_ATPase PF00122.15 KEY69618.1 - 1.5e-23 83.0 0.1 3.1e-23 82.0 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KEY69618.1 - 3.4e-19 69.7 0.3 9.9e-19 68.2 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEY69618.1 - 1.3e-15 58.4 1.3 1.1e-14 55.3 0.9 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEY69618.1 - 2.9e-11 43.1 0.0 7.3e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEY69618.1 - 0.0011 18.5 0.3 0.0047 16.5 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KEY69618.1 - 0.075 13.2 0.5 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase CaMBD PF02888.11 KEY69618.1 - 7.4 6.4 6.9 11 5.8 2.1 2.6 2 0 0 2 2 2 0 Calmodulin binding domain Cript PF10235.4 KEY69619.1 - 4e-31 107.2 10.1 4e-31 107.2 7.0 1.5 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DUF2039 PF10217.4 KEY69619.1 - 0.001 19.0 11.2 0.0067 16.4 5.8 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) DZR PF12773.2 KEY69619.1 - 0.015 15.0 10.9 0.22 11.3 6.2 2.6 2 1 1 3 3 3 0 Double zinc ribbon Ribosomal_L32p PF01783.18 KEY69619.1 - 0.33 11.1 7.9 0.3 11.3 2.6 2.5 2 1 1 3 3 3 0 Ribosomal L32p protein family zinc_ribbon_2 PF13240.1 KEY69619.1 - 1.2 8.7 9.7 5.9 6.5 3.7 3.0 2 1 0 2 2 2 0 zinc-ribbon domain zf-FPG_IleRS PF06827.9 KEY69619.1 - 3.4 7.4 7.0 12 5.7 1.3 2.9 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS zf-RING_5 PF14634.1 KEY69619.1 - 8.9 6.1 12.7 0.44 10.3 2.4 2.8 2 1 0 3 3 3 0 zinc-RING finger domain zf-ribbon_3 PF13248.1 KEY69619.1 - 9.1 5.6 8.6 20 4.5 0.6 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Abhydrolase_6 PF12697.2 KEY69620.1 - 7.4e-29 101.2 0.9 1.1e-28 100.7 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY69620.1 - 3.1e-12 46.5 0.0 5e-12 45.8 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY69620.1 - 4.5e-10 39.4 0.0 1.9e-09 37.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KEY69620.1 - 0.0068 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein AAA_33 PF13671.1 KEY69621.1 - 4e-13 49.4 0.0 5.8e-13 48.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEY69621.1 - 5.5e-12 45.2 0.0 8.6e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KEY69621.1 - 1.8e-07 31.5 0.0 8.9e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEY69621.1 - 1.8e-05 25.5 0.0 3.4e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 KEY69621.1 - 0.00034 20.3 0.0 0.00044 19.9 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_28 PF13521.1 KEY69621.1 - 0.0045 16.9 0.0 0.0052 16.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 KEY69621.1 - 0.0059 16.2 0.3 0.39 10.3 0.2 2.3 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.5 KEY69621.1 - 0.01 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CoaE PF01121.15 KEY69621.1 - 0.023 14.0 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_16 PF13191.1 KEY69621.1 - 0.088 12.7 0.1 0.13 12.2 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AvrPphF-ORF-2 PF09143.5 KEY69621.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 AvrPphF-ORF-2 Pinin_SDK_memA PF04696.8 KEY69622.1 - 7.1e-28 96.8 17.7 1.3e-27 95.9 12.2 1.5 1 0 0 1 1 1 1 pinin/SDK/memA/ protein conserved region PHF5 PF03660.9 KEY69623.1 - 1.6e-51 172.8 10.6 1.9e-51 172.6 7.3 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 KEY69623.1 - 1.1 9.1 15.8 19 5.1 10.1 2.8 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.1 KEY69623.1 - 1.4 8.6 15.7 3 7.6 0.5 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PolC_DP2 PF03833.8 KEY69623.1 - 4.1 4.9 5.7 3.9 5.0 4.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PHD PF00628.24 KEY69623.1 - 7.1 6.3 15.4 0.21 11.2 4.5 2.5 1 1 1 2 2 2 0 PHD-finger Pro-rich_19 PF15455.1 KEY69624.1 - 0.012 14.6 3.1 0.02 13.9 2.1 1.2 1 0 0 1 1 1 0 Proline-rich 19 Mem_trans PF03547.13 KEY69624.1 - 0.029 12.6 0.1 0.047 11.9 0.0 1.2 1 0 0 1 1 1 0 Membrane transport protein CAF-1_p150 PF11600.3 KEY69624.1 - 0.079 12.3 18.1 0.062 12.6 8.1 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Pex26 PF07163.7 KEY69624.1 - 0.15 10.9 2.1 0.36 9.6 1.5 1.7 1 0 0 1 1 1 0 Pex26 protein DUF1451 PF07295.6 KEY69624.1 - 0.38 10.5 9.1 0.67 9.7 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) DDHD PF02862.12 KEY69624.1 - 5.9 6.6 7.3 1.7 8.4 2.9 1.6 2 0 0 2 2 2 0 DDHD domain DUF3635 PF12330.3 KEY69625.1 - 2.7e-06 27.3 0.1 4.5e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) APH PF01636.18 KEY69625.1 - 0.021 14.5 1.1 0.066 12.9 0.8 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF1682 PF07946.9 KEY69626.1 - 2.1e-103 345.5 0.5 2.5e-103 345.3 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Tom37_C PF11801.3 KEY69626.1 - 0.27 11.1 7.5 0.51 10.1 5.2 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF77 PF01910.12 KEY69627.1 - 2.3e-28 97.6 2.3 2.3e-28 97.6 1.6 1.3 2 0 0 2 2 2 1 Domain of unknown function DUF77 Polysacc_deac_1 PF01522.16 KEY69627.1 - 0.01 15.4 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide deacetylase DUF1335 PF07056.6 KEY69627.1 - 0.024 14.3 0.1 0.059 13.1 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1335) CDC37_N PF03234.9 KEY69629.1 - 3.1e-58 197.0 4.8 3.1e-58 197.0 3.3 2.2 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 KEY69629.1 - 2e-44 151.0 0.7 4.8e-44 149.8 0.0 1.9 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 KEY69629.1 - 1.5e-24 85.7 2.2 1.5e-24 85.7 1.5 2.2 2 0 0 2 2 2 1 Cdc37 C terminal domain XPG_I_2 PF12813.2 KEY69629.1 - 0.06 12.8 0.5 0.73 9.2 0.0 2.4 3 0 0 3 3 3 0 XPG domain containing Spectrin PF00435.16 KEY69629.1 - 0.43 10.8 6.6 0.14 12.4 0.6 2.7 2 0 0 2 2 2 0 Spectrin repeat DUF3535 PF12054.3 KEY69630.1 - 6.1e-137 456.8 0.0 1.6e-135 452.1 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 KEY69630.1 - 7.7e-75 251.4 0.0 1.1e-74 250.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 KEY69630.1 - 1.6e-17 61.9 3.2 0.0048 16.8 0.0 8.2 8 0 0 8 8 8 5 HEAT repeat Helicase_C PF00271.26 KEY69630.1 - 2e-13 49.9 0.0 6.3e-13 48.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 KEY69630.1 - 1.1e-08 35.2 0.7 0.18 12.1 0.0 4.7 3 1 1 4 4 4 3 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 KEY69630.1 - 5.9e-07 29.6 7.9 0.0027 17.9 0.0 6.4 5 2 1 6 6 6 2 HEAT repeats HEAT_EZ PF13513.1 KEY69630.1 - 5.2e-06 26.7 8.2 13 6.3 0.0 8.7 9 0 0 9 9 9 1 HEAT-like repeat CLASP_N PF12348.3 KEY69630.1 - 0.0036 16.7 0.4 0.33 10.2 0.1 3.5 3 1 0 3 3 3 1 CLASP N terminal SMC_N PF02463.14 KEY69631.1 - 3.5e-53 180.0 23.4 2.2e-52 177.4 16.2 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KEY69631.1 - 1.9e-29 102.0 0.0 1.7e-28 98.9 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KEY69631.1 - 3.1e-13 50.3 0.2 1.4e-05 25.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.1 KEY69631.1 - 2.4e-07 30.1 15.6 0.00038 19.6 0.2 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 KEY69631.1 - 5.7e-06 26.7 47.0 5.7e-06 26.7 32.6 8.0 2 2 1 3 3 2 1 AAA domain AAA_29 PF13555.1 KEY69631.1 - 0.00031 20.2 0.0 0.00077 18.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.1 KEY69631.1 - 0.00063 18.9 11.5 0.00063 18.9 7.9 7.3 3 2 3 7 7 7 2 Growth-arrest specific micro-tubule binding DivIC PF04977.10 KEY69631.1 - 0.0064 15.9 3.1 0.0064 15.9 2.2 10.9 7 4 3 10 10 10 1 Septum formation initiator Laminin_II PF06009.7 KEY69631.1 - 0.011 15.5 1.7 0.011 15.5 1.2 8.0 5 2 2 8 8 8 0 Laminin Domain II AAA_13 PF13166.1 KEY69631.1 - 0.2 10.0 0.0 0.042 12.3 10.6 5.8 3 2 3 6 6 5 0 AAA domain ABC_tran PF00005.22 KEY69631.1 - 0.54 10.5 0.0 0.54 10.5 0.0 6.9 3 2 1 4 4 2 0 ABC transporter PCI PF01399.22 KEY69631.1 - 0.99 9.7 8.1 0.11 12.7 0.5 3.2 3 0 0 3 3 3 0 PCI domain MRP-L46 PF11788.3 KEY69632.1 - 1.9e-26 92.8 0.0 3.1e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 KEY69632.1 - 0.024 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain PHD PF00628.24 KEY69633.1 - 2.6e-10 39.7 7.4 2.6e-10 39.7 5.1 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 KEY69633.1 - 4.4e-09 36.0 19.8 2.4e-08 33.6 0.3 3.9 3 1 1 4 4 4 1 Ring finger domain zf-rbx1 PF12678.2 KEY69633.1 - 3.2e-07 30.3 13.0 7.6e-06 25.9 2.4 3.2 2 1 0 2 2 2 2 RING-H2 zinc finger PHD_2 PF13831.1 KEY69633.1 - 4.7e-07 29.0 3.0 4.7e-07 29.0 2.1 2.0 2 0 0 2 2 2 1 PHD-finger zf-RING_5 PF14634.1 KEY69633.1 - 4.5e-05 23.0 0.4 4.5e-05 23.0 0.3 3.5 3 1 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KEY69633.1 - 6.2e-05 22.5 0.5 6.2e-05 22.5 0.3 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEY69633.1 - 7.6e-05 22.2 0.2 7.6e-05 22.2 0.2 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEY69633.1 - 0.00047 19.9 7.9 0.0076 16.0 0.3 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 KEY69633.1 - 0.00051 19.7 4.6 0.0011 18.5 0.8 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.1 KEY69633.1 - 0.002 18.1 0.8 0.002 18.1 0.5 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 KEY69633.1 - 0.002 17.6 5.6 0.002 17.6 0.6 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-PHD-like PF15446.1 KEY69633.1 - 0.013 14.8 1.7 0.033 13.4 0.3 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHF5 PF03660.9 KEY69633.1 - 0.025 14.6 0.7 0.025 14.6 0.5 2.0 2 0 0 2 2 2 0 PHF5-like protein zf-RING_6 PF14835.1 KEY69633.1 - 0.052 13.3 0.4 0.052 13.3 0.3 2.2 2 1 1 3 3 3 0 zf-RING of BARD1-type protein RecR PF02132.10 KEY69633.1 - 1.8 8.0 9.8 2.6 7.5 0.4 3.3 3 0 0 3 3 3 0 RecR protein Ribosomal_L37ae PF01780.14 KEY69634.1 - 4.5e-39 132.1 9.5 5e-39 132.0 6.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 KEY69634.1 - 0.00044 19.9 3.3 0.00067 19.4 2.3 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Sgf11 PF08209.6 KEY69634.1 - 0.0053 16.0 0.4 0.031 13.5 0.0 2.1 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) Elf1 PF05129.8 KEY69634.1 - 0.0077 15.8 0.4 0.011 15.3 0.3 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.6 KEY69634.1 - 0.022 14.3 1.4 0.031 13.9 1.0 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain A2L_zn_ribbon PF08792.5 KEY69634.1 - 0.039 13.4 4.0 0.061 12.8 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-BED PF02892.10 KEY69634.1 - 0.19 11.4 5.4 0.65 9.8 0.4 2.3 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.5 KEY69634.1 - 1 9.3 3.7 1.2 9.1 0.2 2.1 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2 PF00096.21 KEY69634.1 - 3.9 7.9 6.0 1.8 9.0 0.7 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KEY69634.1 - 5.8 7.4 8.8 0.48 10.8 1.0 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Saccharop_dh PF03435.13 KEY69635.1 - 4.3e-21 75.3 0.0 6e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KEY69635.1 - 0.0025 17.8 0.0 0.0056 16.7 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KEY69635.1 - 0.0071 16.6 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 KEY69635.1 - 0.025 13.9 0.0 0.048 13.0 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.5 KEY69635.1 - 0.053 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 KR domain Shikimate_DH PF01488.15 KEY69635.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF155 PF02582.9 KEY69636.1 - 7e-56 188.8 0.4 1.1e-55 188.2 0.3 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Pecanex_C PF05041.10 KEY69636.1 - 0.097 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Pecanex protein (C-terminus) HMG_box PF00505.14 KEY69637.1 - 2.1e-07 31.1 3.9 6.8e-07 29.4 2.7 1.9 1 1 0 1 1 1 1 HMG (high mobility group) box DUF2443 PF10398.4 KEY69637.1 - 0.019 14.7 0.7 0.085 12.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) MDM31_MDM32 PF08118.6 KEY69637.1 - 0.12 10.8 0.3 0.17 10.3 0.2 1.2 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins HMG_box_2 PF09011.5 KEY69637.1 - 0.47 10.8 7.5 0.3 11.4 3.3 2.3 2 1 0 2 2 2 0 HMG-box domain Cpn60_TCP1 PF00118.19 KEY69638.1 - 1.3e-136 456.1 6.8 1.4e-136 455.9 4.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EAL PF00563.15 KEY69638.1 - 0.071 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 EAL domain PH_10 PF15411.1 KEY69639.1 - 6.8e-28 97.1 0.1 1.1e-27 96.4 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 KEY69639.1 - 1.1e-10 41.4 0.0 3.4e-10 39.8 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KEY69639.1 - 1.5e-08 34.5 0.0 2.6e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 KEY69639.1 - 2.5e-07 30.4 6.0 4.6e-07 29.5 4.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KEY69639.1 - 0.00072 19.2 5.3 0.0012 18.4 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KEY69639.1 - 0.0028 17.7 1.4 0.0055 16.7 1.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KEY69639.1 - 0.012 15.6 4.9 0.023 14.7 3.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEY69639.1 - 0.038 13.6 5.5 0.072 12.7 3.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1147 PF06615.6 KEY69639.1 - 0.16 11.8 0.6 0.47 10.3 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) zf-RING-like PF08746.6 KEY69639.1 - 0.69 9.9 4.7 1.4 8.9 3.3 1.6 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.1 KEY69639.1 - 1 9.1 3.3 2.6 7.8 0.5 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 KEY69639.1 - 2.4 7.8 3.5 4.6 6.8 2.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4244 PF14029.1 KEY69640.1 - 0.023 13.8 0.3 0.023 13.8 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) U3_snoRNA_assoc PF08297.6 KEY69642.1 - 5.7e-06 26.4 0.4 5.7e-06 26.4 0.3 3.6 3 2 0 3 3 3 1 U3 snoRNA associated Muted PF14942.1 KEY69642.1 - 2.7 7.8 11.0 7.1 6.4 7.6 1.8 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein UPF0172 PF03665.8 KEY69642.1 - 3.6 7.0 6.2 7.3 6.0 4.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) TPR_11 PF13414.1 KEY69643.1 - 2.6e-07 30.2 1.6 8.2e-07 28.5 0.1 2.2 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.1 KEY69643.1 - 5.2e-07 29.9 0.3 1.3e-06 28.6 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 KEY69643.1 - 5.9e-07 29.5 0.1 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KEY69643.1 - 5.7e-05 22.9 0.7 0.0002 21.2 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEY69643.1 - 7.6e-05 22.3 0.1 0.27 11.2 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEY69643.1 - 0.0056 16.3 2.0 0.08 12.7 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEY69643.1 - 0.01 16.4 2.9 0.04 14.6 0.2 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEY69643.1 - 0.015 14.9 0.2 3.6 7.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEY69643.1 - 0.024 14.4 2.2 6.5 6.7 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEY69643.1 - 0.026 14.9 1.1 0.76 10.3 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 KEY69643.1 - 0.048 14.0 0.1 0.7 10.4 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_21 PF09976.4 KEY69643.1 - 0.059 13.3 0.3 0.12 12.2 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEY69643.1 - 0.096 13.3 5.0 9.2 7.2 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEY69643.1 - 0.14 12.0 5.7 3.2 7.8 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat FAD_binding_7 PF03441.9 KEY69644.1 - 1.4e-83 280.2 0.0 2e-83 279.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KEY69644.1 - 6.1e-33 113.8 0.0 1.8e-32 112.3 0.0 1.7 2 0 0 2 2 2 1 DNA photolyase p12I PF12233.3 KEY69644.1 - 0.036 14.3 0.2 7 6.9 0.1 2.4 2 0 0 2 2 2 0 Human adult T cell leukemia/lymphoma virus protein DUF3760 PF12586.3 KEY69644.1 - 0.037 13.8 0.0 0.39 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) XPC-binding PF09280.6 KEY69646.1 - 1.1e-23 82.4 12.1 2.1e-23 81.5 8.4 1.4 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 KEY69646.1 - 2.8e-20 71.5 6.2 1.6e-09 37.3 0.2 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 KEY69646.1 - 6.6e-11 41.4 0.1 7.9e-07 28.3 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family MCM_N PF14551.1 KEY69646.1 - 0.00086 19.7 0.3 0.0021 18.5 0.1 1.6 2 0 0 2 2 2 1 MCM N-terminal domain UBA_3 PF09288.5 KEY69646.1 - 0.0016 17.9 0.0 1.9 8.1 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Rad60-SLD PF11976.3 KEY69646.1 - 0.0028 17.3 0.2 0.037 13.7 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.11 KEY69646.1 - 0.094 12.2 0.0 0.4 10.2 0.0 2.0 2 0 0 2 2 2 0 CUE domain PRCC PF10253.4 KEY69646.1 - 9.4 6.8 14.8 6.4 7.4 0.5 2.2 1 1 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Myb_DNA-binding PF00249.26 KEY69647.1 - 1.5e-06 28.1 0.0 3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEY69647.1 - 0.0022 18.0 0.0 0.0046 17.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain BRE1 PF08647.6 KEY69648.1 - 5.3e-28 96.8 8.0 5.3e-28 96.8 5.5 7.0 4 2 3 7 7 7 1 BRE1 E3 ubiquitin ligase zf-C3HC4 PF00097.20 KEY69648.1 - 2.9e-08 33.2 11.1 5.1e-08 32.4 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEY69648.1 - 3.2e-08 33.1 8.1 5e-08 32.4 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEY69648.1 - 4.3e-08 33.0 10.2 6.9e-08 32.3 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEY69648.1 - 3.2e-06 26.8 7.3 5.5e-06 26.1 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KEY69648.1 - 7.6e-06 25.5 10.5 1.2e-05 24.8 7.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KEY69648.1 - 0.00047 19.8 6.3 0.0012 18.5 4.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Phage_GP20 PF06810.6 KEY69648.1 - 0.0014 18.0 8.8 0.0014 18.0 6.1 6.6 3 1 4 7 7 7 1 Phage minor structural protein GP20 zf-RING_6 PF14835.1 KEY69648.1 - 0.0039 16.9 2.3 0.011 15.5 1.6 1.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 KEY69648.1 - 0.0053 16.2 2.8 0.0096 15.4 2.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 KEY69648.1 - 0.0082 15.9 7.1 0.015 15.1 4.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KEY69648.1 - 0.051 13.1 7.3 0.15 11.6 5.1 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Retrotrans_gag PF03732.12 KEY69648.1 - 0.31 11.1 12.6 0.22 11.6 0.2 4.5 3 2 0 3 3 3 0 Retrotransposon gag protein FYVE PF01363.16 KEY69648.1 - 1 9.3 11.3 9.8 6.1 7.8 2.3 1 1 1 2 2 2 0 FYVE zinc finger Reo_sigmaC PF04582.7 KEY69648.1 - 3.7 6.6 25.0 0.97 8.5 3.0 3.8 2 1 3 5 5 5 0 Reovirus sigma C capsid protein DUF1183 PF06682.7 KEY69649.1 - 3e-82 276.7 17.3 7.2e-82 275.5 12.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) ATG27 PF09451.5 KEY69649.1 - 0.075 12.2 1.1 0.12 11.5 0.2 1.7 2 0 0 2 2 2 0 Autophagy-related protein 27 TMEMspv1-c74-12 PF11044.3 KEY69649.1 - 0.13 11.8 2.3 0.22 11.1 1.6 1.3 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein ABC_membrane PF00664.18 KEY69651.1 - 2.4e-89 299.3 39.9 1.6e-45 155.7 12.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KEY69651.1 - 8.2e-68 226.9 0.0 1.1e-33 116.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KEY69651.1 - 5.5e-13 48.6 0.0 0.0017 17.6 0.0 4.0 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEY69651.1 - 3.1e-10 40.5 0.2 0.91 9.4 0.0 4.3 3 1 1 4 4 4 4 AAA domain AAA_29 PF13555.1 KEY69651.1 - 4.8e-09 35.6 0.5 0.00031 20.2 0.2 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KEY69651.1 - 5.2e-08 33.0 2.5 0.0027 17.7 0.0 3.5 3 1 1 4 4 4 2 AAA ATPase domain ABC_ATPase PF09818.4 KEY69651.1 - 5.6e-08 31.8 3.6 0.005 15.4 0.2 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 KEY69651.1 - 6.8e-07 30.1 0.0 0.042 14.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KEY69651.1 - 9.8e-07 28.0 0.1 0.14 11.3 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KEY69651.1 - 2e-05 24.1 1.5 0.16 11.3 0.0 3.5 4 0 0 4 4 4 2 AAA domain AAA_14 PF13173.1 KEY69651.1 - 0.00021 21.1 0.0 1.4 8.7 0.0 3.6 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 KEY69651.1 - 0.00044 20.3 1.1 3 8.0 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.1 KEY69651.1 - 0.0022 17.8 0.0 3.3 7.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KEY69651.1 - 0.0043 17.3 0.0 2.7 8.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 KEY69651.1 - 0.0044 15.7 0.2 0.38 9.3 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_5 PF07728.9 KEY69651.1 - 0.0054 16.4 1.0 7 6.3 0.0 3.7 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 KEY69651.1 - 0.018 14.4 1.8 0.71 9.3 0.0 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF87 PF01935.12 KEY69651.1 - 0.02 14.7 3.2 2.9 7.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_23 PF13476.1 KEY69651.1 - 0.026 14.8 1.7 1.7 8.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 KEY69651.1 - 0.045 13.7 4.0 0.69 9.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_10 PF12846.2 KEY69651.1 - 0.045 13.1 4.1 15 4.9 0.3 3.9 4 0 0 4 4 4 0 AAA-like domain MobB PF03205.9 KEY69651.1 - 0.053 13.2 0.9 15 5.2 0.0 3.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 KEY69651.1 - 0.062 13.2 8.5 1.3 8.9 0.1 3.8 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 KEY69651.1 - 0.15 12.2 0.1 17 5.6 0.0 3.1 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.18 KEY69651.1 - 0.22 11.5 0.9 13 5.7 0.0 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase CDC45 PF02724.9 KEY69652.1 - 0.007 14.4 0.5 0.0076 14.3 0.3 1.1 1 0 0 1 1 1 1 CDC45-like protein Sporozoite_P67 PF05642.6 KEY69652.1 - 0.29 8.9 5.0 0.4 8.5 3.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cupin_5 PF06172.6 KEY69653.1 - 2.8e-38 130.9 0.0 3.2e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) DUF3425 PF11905.3 KEY69654.1 - 3.4e-32 111.1 1.6 6.5e-32 110.2 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KEY69654.1 - 0.15 12.0 11.4 0.4 10.6 7.9 1.7 1 1 0 1 1 1 0 bZIP transcription factor DUF904 PF06005.7 KEY69654.1 - 4.1 7.7 8.9 0.59 10.4 2.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Sperm_Ag_HE2 PF05324.8 KEY69655.1 - 0.046 13.6 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 Sperm antigen HE2 E1-E2_ATPase PF00122.15 KEY69656.1 - 2.4e-64 216.5 7.5 4.8e-64 215.5 5.2 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KEY69656.1 - 7.1e-22 78.8 0.0 1.6e-21 77.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEY69656.1 - 5.5e-12 46.2 0.0 1.4e-11 44.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEY69656.1 - 1.1e-10 40.8 0.0 2.7e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KEY69656.1 - 0.0015 18.1 0.1 0.003 17.1 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DMA PF03474.9 KEY69656.1 - 0.039 13.8 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 DMRTA motif Hydrolase_like2 PF13246.1 KEY69656.1 - 0.04 13.8 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit RRM_5 PF13893.1 KEY69657.1 - 1.6e-05 24.6 0.0 3.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEY69657.1 - 2.4e-05 23.8 0.0 5.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY69657.1 - 0.00035 20.4 0.1 0.00083 19.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 KEY69657.1 - 0.00078 19.6 0.0 0.0024 18.0 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase II-binding domain. UPF0020 PF01170.13 KEY69657.1 - 0.021 14.4 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Citrate_synt PF00285.16 KEY69658.1 - 5.8e-102 341.0 0.0 7e-102 340.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 KEY69658.1 - 0.04 13.3 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 Eclosion hormone Mito_carr PF00153.22 KEY69659.1 - 5.7e-28 96.4 5.0 9.1e-12 44.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein MBD PF01429.14 KEY69659.1 - 0.035 13.6 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyl-CpG binding domain WD40 PF00400.27 KEY69660.1 - 4.9e-05 23.0 17.7 0.057 13.3 0.1 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat AMP-binding PF00501.23 KEY69661.1 - 1.3e-81 274.1 0.0 1.6e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Arginase PF00491.16 KEY69661.1 - 0.07 12.4 0.0 7 5.8 0.0 2.2 2 0 0 2 2 2 0 Arginase family MARVEL PF01284.18 KEY69662.1 - 7.3e-15 55.0 14.4 9.1e-15 54.7 10.0 1.0 1 0 0 1 1 1 1 Membrane-associating domain Cys_Met_Meta_PP PF01053.15 KEY69663.1 - 5.8e-143 475.8 0.0 9.7e-143 475.1 0.0 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KEY69663.1 - 4.3e-13 49.0 0.2 7.3e-13 48.2 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 KEY69663.1 - 2.1e-08 33.5 0.0 4.2e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KEY69663.1 - 3e-07 29.5 0.3 5.1e-07 28.7 0.2 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KEY69663.1 - 5.1e-07 29.1 0.0 9.4e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 KEY69663.1 - 0.00069 18.0 0.1 0.001 17.4 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SLA_LP_auto_ag PF05889.8 KEY69663.1 - 0.073 11.5 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) GDC-P PF02347.11 KEY69663.1 - 0.11 11.1 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage system P-protein DUF2012 PF09430.5 KEY69664.1 - 2.1e-25 88.9 0.0 2.8e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) WW PF00397.21 KEY69665.1 - 1.7e-07 30.9 5.6 3.4e-07 30.0 3.9 1.5 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.4 KEY69665.1 - 0.38 10.7 20.7 0.036 14.1 10.7 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Pex14_N PF04695.8 KEY69665.1 - 2.7 8.0 4.8 1.5 8.8 1.6 1.7 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Choline_transpo PF04515.7 KEY69666.1 - 9e-17 60.8 29.6 5.1e-14 51.7 11.8 3.4 3 1 0 3 3 3 2 Plasma-membrane choline transporter DUF1993 PF09351.5 KEY69667.1 - 6.5e-45 152.9 0.0 7.4e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Ras PF00071.17 KEY69668.1 - 4.5e-51 172.4 0.0 7.3e-40 135.9 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KEY69668.1 - 9.6e-17 61.5 0.0 3.7e-16 59.6 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEY69668.1 - 2.6e-12 46.3 0.0 8.5e-12 44.6 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEY69668.1 - 3.6e-08 33.0 0.0 1.3e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KEY69668.1 - 2.2e-07 30.2 0.0 3.9e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KEY69668.1 - 5.4e-05 23.1 0.0 0.00012 21.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 KEY69668.1 - 0.0096 15.4 0.1 1.1 8.7 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 KEY69668.1 - 0.014 15.5 0.0 0.046 13.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KEY69668.1 - 0.088 12.7 0.1 0.29 11.1 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 KEY69668.1 - 0.12 11.7 0.0 0.34 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 KEY69668.1 - 0.15 12.3 1.2 0.66 10.2 0.8 2.1 1 1 0 1 1 1 0 ABC transporter PMT PF02366.13 KEY69669.1 - 1.5e-83 279.8 14.6 1.5e-83 279.8 10.1 2.5 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KEY69669.1 - 4.9e-40 137.0 0.9 6.6e-40 136.6 0.6 1.2 1 0 0 1 1 1 1 MIR domain zf-CHY PF05495.7 KEY69670.1 - 2e-17 63.0 19.8 2e-17 63.0 13.7 4.2 3 1 1 4 4 4 1 CHY zinc finger zinc_ribbon_6 PF14599.1 KEY69670.1 - 2.9e-17 62.2 0.0 2.9e-17 62.2 0.0 4.0 5 1 0 5 5 5 1 Zinc-ribbon zf-RING_2 PF13639.1 KEY69670.1 - 1.1e-08 34.7 9.7 1.1e-08 34.7 6.7 4.2 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEY69670.1 - 2.3e-08 33.9 8.9 2.3e-08 33.9 6.1 4.7 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEY69670.1 - 2.3e-07 30.3 8.2 2.3e-07 30.3 5.7 5.4 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY69670.1 - 2e-06 27.3 8.7 2e-06 27.3 6.1 6.2 3 2 2 5 5 5 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KEY69670.1 - 1.3e-05 24.7 6.2 1.3e-05 24.7 4.3 4.7 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) CENP-B_dimeris PF09026.5 KEY69670.1 - 1.6 8.9 8.4 2.9 8.1 5.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 KEY69670.1 - 4.3 6.8 8.2 7.7 6.0 5.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin Rtf2 PF04641.7 KEY69670.1 - 6 5.9 14.3 0.17 11.0 4.6 2.1 1 1 1 2 2 2 0 Rtf2 RING-finger MOZART1 PF12554.3 KEY69671.1 - 2.2e-26 91.0 0.9 2.9e-26 90.6 0.6 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated MOZART2 PF12926.2 KEY69671.1 - 0.028 13.9 0.1 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated WXG100 PF06013.7 KEY69671.1 - 0.051 13.5 0.3 1.2 9.2 0.0 2.0 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF3893 PF13032.1 KEY69671.1 - 0.087 12.9 0.4 0.094 12.8 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3893) Spindle_Spc25 PF08234.7 KEY69672.1 - 5.4e-22 77.5 0.0 1.2e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 DUF948 PF06103.6 KEY69672.1 - 0.64 9.9 2.8 0.96 9.3 0.8 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.8 KEY69672.1 - 2.1 7.3 8.1 2.9 6.8 5.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein Atg14 PF10186.4 KEY69672.1 - 3.5 6.4 9.8 5.4 5.8 6.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1843 PF08898.5 KEY69672.1 - 3.6 7.6 8.3 0.23 11.4 1.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) PITH PF06201.8 KEY69673.1 - 2.9e-44 150.5 0.0 4.4e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 PITH domain Rrn6 PF10214.4 KEY69673.1 - 2.2e-33 115.3 0.0 1.9e-32 112.2 0.0 2.3 2 1 0 2 2 2 1 RNA polymerase I-specific transcription-initiation factor Ribosomal_L3 PF00297.17 KEY69674.1 - 1.2e-32 113.3 2.2 1.3e-31 109.9 1.5 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 Coa1 PF08695.5 KEY69675.1 - 5.2e-37 125.9 0.0 6.7e-37 125.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 PRA1 PF03208.14 KEY69676.1 - 0.097 12.0 0.4 6.5 6.0 0.0 2.1 2 0 0 2 2 2 0 PRA1 family protein Ank_2 PF12796.2 KEY69677.1 - 3e-35 120.4 9.1 2.6e-14 53.2 0.1 4.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) SPX PF03105.14 KEY69677.1 - 1.5e-29 103.6 13.6 9.2e-26 91.2 9.4 2.7 1 1 0 1 1 1 1 SPX domain Ank_4 PF13637.1 KEY69677.1 - 2.6e-27 94.6 6.4 1.1e-09 38.5 0.0 5.6 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 KEY69677.1 - 1.6e-23 81.2 11.6 0.00053 19.6 0.0 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 KEY69677.1 - 1.1e-19 68.5 11.6 0.0026 17.8 0.0 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 KEY69677.1 - 1.7e-18 66.2 12.6 0.00072 19.7 0.0 7.9 2 1 6 8 8 8 6 Ankyrin repeats (many copies) CUE PF02845.11 KEY69677.1 - 4.4e-13 48.4 0.0 1.3e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 CUE domain GDPD PF03009.12 KEY69677.1 - 3e-09 36.7 0.0 1.1e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family OB_NTP_bind PF07717.11 KEY69678.1 - 2.5e-21 75.6 0.0 4.9e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KEY69678.1 - 3.5e-21 75.1 0.1 6.9e-21 74.1 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KEY69678.1 - 2.3e-12 46.6 0.0 4.9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KEY69678.1 - 4.6e-05 23.5 0.0 0.00014 22.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KEY69678.1 - 0.018 14.5 2.2 0.13 11.6 1.0 2.5 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_30 PF13604.1 KEY69678.1 - 0.031 13.8 0.0 0.076 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KEY69678.1 - 0.033 13.0 0.0 0.064 12.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 KEY69678.1 - 0.097 12.5 0.2 15 5.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 KEY69678.1 - 0.12 11.8 0.1 0.49 9.8 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SKG6 PF08693.5 KEY69679.1 - 0.0014 17.8 0.2 0.0024 17.1 0.1 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SKG6 PF08693.5 KEY69680.1 - 2.6e-10 39.4 3.1 7.1e-10 38.0 2.2 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain AJAP1_PANP_C PF15298.1 KEY69680.1 - 0.0022 17.9 8.4 0.0022 17.9 5.8 2.6 1 1 1 2 2 1 1 AJAP1/PANP C-terminus DUF3301 PF11743.3 KEY69680.1 - 0.032 13.7 0.1 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) CcmD PF04995.9 KEY69680.1 - 0.034 13.8 0.6 0.06 13.0 0.4 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF4448 PF14610.1 KEY69680.1 - 0.034 13.6 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4366 PF14283.1 KEY69680.1 - 0.042 13.2 1.8 0.13 11.6 0.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Herpes_gE PF02480.11 KEY69680.1 - 0.07 11.3 0.1 0.07 11.3 0.1 2.9 1 1 1 3 3 3 0 Alphaherpesvirus glycoprotein E Rax2 PF12768.2 KEY69680.1 - 0.099 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF4381 PF14316.1 KEY69680.1 - 0.11 12.5 0.1 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2207 PF09972.4 KEY69680.1 - 0.12 10.9 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TFIIA PF03153.8 KEY69680.1 - 2.6 7.8 12.0 4.8 6.9 8.3 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mitofilin PF09731.4 KEY69680.1 - 6.2 5.3 5.3 7.9 5.0 3.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein COesterase PF00135.23 KEY69681.1 - 2.6e-66 224.4 0.0 3.5e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEY69681.1 - 8.2e-07 28.8 3.4 1.6e-06 27.8 1.6 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY69681.1 - 0.0057 16.4 2.1 0.012 15.4 0.5 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Phage_HK97_TLTM PF06120.6 KEY69682.1 - 0.056 12.7 0.6 0.098 11.9 0.4 1.4 1 0 0 1 1 1 0 Tail length tape measure protein DASH_Dad2 PF08654.5 KEY69683.1 - 3.8e-33 113.5 1.4 5.5e-33 113.0 1.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad2 Seryl_tRNA_N PF02403.17 KEY69683.1 - 0.038 14.0 0.2 0.086 12.8 0.1 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DASH_Duo1 PF08651.5 KEY69683.1 - 0.076 12.6 0.1 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Duo1 Baculo_PEP_C PF04513.7 KEY69683.1 - 0.14 12.0 0.8 0.21 11.4 0.5 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Shugoshin_C PF07557.6 KEY69684.1 - 1.8e-11 43.2 6.7 1.8e-11 43.2 4.6 3.5 3 0 0 3 3 3 1 Shugoshin C terminus Shugoshin_N PF07558.6 KEY69684.1 - 2.2e-08 33.6 6.2 2.2e-08 33.6 4.3 2.3 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region AKNA PF12443.3 KEY69684.1 - 0.0017 18.3 0.3 0.0065 16.4 0.2 2.0 1 0 0 1 1 1 1 AT-hook-containing transcription factor Mod_r PF07200.8 KEY69684.1 - 0.13 12.1 2.7 0.3 10.9 1.9 1.6 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Metallophos_2 PF12850.2 KEY69685.1 - 1.5e-13 50.8 0.0 1.9e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KEY69685.1 - 0.054 12.8 0.1 0.97 8.7 0.0 2.2 1 1 0 2 2 2 0 Calcineurin-like phosphoesterase NUC173 PF08161.7 KEY69686.1 - 1.4e-77 259.5 1.6 5.7e-76 254.2 0.1 3.2 3 0 0 3 3 3 1 NUC173 domain HEAT_2 PF13646.1 KEY69686.1 - 0.00054 20.1 2.4 1.6 9.0 0.1 4.8 3 2 0 3 3 3 2 HEAT repeats Vac14_Fab1_bd PF12755.2 KEY69686.1 - 0.0079 16.5 0.4 5.5 7.4 0.0 3.7 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 KEY69686.1 - 0.017 15.1 6.2 0.5 10.5 0.0 4.5 6 0 0 6 6 6 0 HEAT repeat DUF2293 PF10056.4 KEY69687.1 - 5.6e-26 90.3 0.8 1.4e-25 89.0 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) bZIP_1 PF00170.16 KEY69688.1 - 5.7e-11 42.1 11.6 1.4e-10 40.9 8.0 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KEY69688.1 - 0.00029 20.5 10.9 0.00029 20.5 7.6 2.7 2 0 0 2 2 2 1 Basic region leucine zipper DivIC PF04977.10 KEY69688.1 - 7.3 6.1 24.6 0.046 13.1 0.8 3.0 3 0 0 3 3 3 0 Septum formation initiator HET PF06985.6 KEY69689.1 - 2.8e-35 121.4 0.1 4.7e-35 120.7 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) His_Phos_2 PF00328.17 KEY69690.1 - 5.4e-07 29.2 0.0 2.3e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) JmjC PF02373.17 KEY69691.1 - 7.9e-38 129.2 0.1 2.3e-37 127.7 0.1 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 KEY69691.1 - 6.1e-21 74.4 2.2 1.2e-20 73.5 1.6 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KEY69691.1 - 2.5e-20 72.3 3.0 2.5e-20 72.3 2.1 2.5 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.12 KEY69691.1 - 2.8e-14 52.3 0.8 6.7e-14 51.1 0.6 1.7 1 0 0 1 1 1 1 jmjN domain Pkinase PF00069.20 KEY69692.1 - 8.7e-38 129.9 0.0 1.1e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY69692.1 - 1.1e-23 83.5 0.0 1.4e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY69692.1 - 2.2e-05 23.5 0.0 5.6e-05 22.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KEY69692.1 - 0.0034 16.4 0.1 0.005 15.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GlcNAc_2-epim PF07221.6 KEY69692.1 - 0.068 12.1 0.1 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Aminotran_1_2 PF00155.16 KEY69693.1 - 4.2e-67 226.6 0.0 4.8e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KEY69693.1 - 2.5e-06 26.8 0.0 3.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KEY69693.1 - 0.00037 19.6 0.0 0.00063 18.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KEY69693.1 - 0.00094 17.5 0.0 0.0017 16.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KEY69693.1 - 0.13 10.9 0.0 0.29 9.8 0.0 1.6 1 1 0 1 1 1 0 Aminotransferase class-V Ald_Xan_dh_C2 PF02738.13 KEY69694.1 - 7.1e-193 641.8 0.1 9.6e-193 641.4 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 KEY69694.1 - 3.6e-49 166.4 0.0 6.8e-49 165.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 KEY69694.1 - 5.8e-33 113.2 0.3 1.4e-32 112.0 0.2 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 KEY69694.1 - 1.9e-30 104.8 0.5 1.1e-29 102.4 0.0 2.5 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 KEY69694.1 - 4.2e-29 100.2 0.0 9.1e-29 99.1 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 KEY69694.1 - 3.7e-07 29.7 1.8 5.8e-07 29.1 0.1 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Sigma70_r3 PF04539.11 KEY69694.1 - 0.01 15.6 0.2 1.6 8.6 0.1 3.0 3 0 0 3 3 3 0 Sigma-70 region 3 PAS PF00989.19 KEY69695.1 - 0.17 11.6 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 PAS fold SPO22 PF08631.5 KEY69696.1 - 1.9e-51 174.8 0.0 3.7e-50 170.5 0.0 2.6 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 KEY69696.1 - 2.7e-07 30.4 6.4 0.00077 19.3 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat Fungal_trans PF04082.13 KEY69697.1 - 5.4e-28 97.5 0.0 1e-27 96.6 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY69697.1 - 5.7e-08 32.5 13.7 1.2e-07 31.4 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L37ae PF01780.14 KEY69697.1 - 0.94 9.3 5.2 2 8.3 3.6 1.5 1 0 0 1 1 1 0 Ribosomal L37ae protein family Ufd2P_core PF10408.4 KEY69698.1 - 1.6e-184 614.7 7.2 1.9e-184 614.4 5.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 KEY69698.1 - 5.2e-23 80.8 2.0 1.8e-22 79.0 1.4 2.0 1 0 0 1 1 1 1 U-box domain MCM_N PF14551.1 KEY69698.1 - 0.059 13.8 0.6 0.2 12.1 0.4 2.0 1 0 0 1 1 1 0 MCM N-terminal domain CCDC-167 PF15188.1 KEY69698.1 - 0.1 12.5 8.4 0.023 14.6 1.1 3.0 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 zf-TRAF PF02176.13 KEY69699.1 - 4.5e-14 52.5 24.4 1.8e-08 34.6 2.7 3.6 2 1 1 3 3 3 3 TRAF-type zinc finger zf-C3HC4 PF00097.20 KEY69699.1 - 1.3e-08 34.2 8.6 1.3e-08 34.2 5.9 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEY69699.1 - 2.3e-08 33.9 9.5 2.3e-08 33.9 6.6 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KEY69699.1 - 2.1e-07 30.6 10.1 2.1e-07 30.6 7.0 3.0 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KEY69699.1 - 5.6e-07 29.2 9.3 5.6e-07 29.2 6.4 3.2 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 KEY69699.1 - 1.1e-06 28.1 5.0 1.1e-06 28.1 3.4 3.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY69699.1 - 8.9e-06 25.3 6.5 8.9e-06 25.3 4.5 3.4 2 1 1 3 3 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KEY69699.1 - 0.00016 21.3 5.8 0.00051 19.7 4.0 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 KEY69699.1 - 0.0036 16.7 5.2 0.0036 16.7 3.6 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 KEY69699.1 - 0.011 15.7 1.3 0.045 13.7 0.2 2.3 2 0 0 2 2 2 0 U-box domain zf-Apc11 PF12861.2 KEY69699.1 - 0.016 15.0 2.5 0.016 15.0 1.8 2.0 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 KEY69699.1 - 2.1 8.1 12.0 0.037 13.7 2.9 2.2 2 1 1 3 3 2 0 zf-RING of BARD1-type protein Sina PF03145.11 KEY69699.1 - 7.4 6.1 16.5 0.69 9.5 1.4 3.1 2 1 1 3 3 3 0 Seven in absentia protein family Abhydrolase_3 PF07859.8 KEY69700.1 - 2e-34 119.0 0.0 8e-23 81.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KEY69700.1 - 0.25 9.9 0.0 0.4 9.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Pyridoxal_deC PF00282.14 KEY69701.1 - 4.5e-71 239.2 0.0 6.1e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KEY69701.1 - 6.4e-06 25.1 0.0 9.5e-06 24.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_3 PF00202.16 KEY69702.1 - 1.9e-97 326.1 0.0 2.3e-97 325.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KEY69702.1 - 0.00041 19.4 0.0 0.0012 17.8 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II ATG27 PF09451.5 KEY69703.1 - 3.4e-72 242.9 0.1 4.4e-72 242.5 0.1 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 KEY69703.1 - 0.00011 22.0 0.1 0.77 9.5 0.0 3.1 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat Toprim_2 PF13155.1 KEY69703.1 - 0.096 13.0 0.1 0.23 11.7 0.1 1.7 1 1 0 1 1 1 0 Toprim-like Spt20 PF12090.3 KEY69704.1 - 6.9e-39 133.0 0.0 6.9e-39 133.0 0.0 4.7 4 1 0 4 4 4 2 Spt20 family Hexapep PF00132.19 KEY69706.1 - 1.6e-07 30.5 0.2 0.00021 20.6 0.1 2.7 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KEY69706.1 - 0.0006 19.9 0.0 0.0013 18.8 0.0 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KEY69706.1 - 0.025 14.1 6.3 0.48 10.0 0.2 3.0 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 KEY69706.1 - 0.041 12.4 0.2 0.06 11.9 0.1 1.2 1 0 0 1 1 1 0 L-fucokinase zf-C2H2_4 PF13894.1 KEY69707.1 - 3.3e-05 23.9 14.4 0.016 15.5 0.3 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY69707.1 - 0.00011 22.3 17.4 0.007 16.6 3.3 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type DUF3505 PF12013.3 KEY69707.1 - 0.045 14.0 2.8 0.12 12.5 1.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) PyrI_C PF02748.10 KEY69707.1 - 0.072 12.5 0.7 3.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain RPAP2_Rtr1 PF04181.8 KEY69707.1 - 0.081 13.0 1.8 0.2 11.7 1.2 1.6 1 0 0 1 1 1 0 Rtr1/RPAP2 family LRR_6 PF13516.1 KEY69708.1 - 3.3e-06 26.6 2.0 0.022 14.8 0.0 3.7 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.2 KEY69708.1 - 0.0028 17.2 7.7 2.4 7.8 0.0 3.8 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEY69708.1 - 0.0035 17.1 5.1 1.6 9.0 0.0 4.3 3 1 0 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 KEY69708.1 - 0.0044 16.9 3.9 7.4 7.2 0.0 4.9 3 1 0 3 3 3 1 Leucine rich repeat LRR_8 PF13855.1 KEY69708.1 - 0.011 15.4 6.8 1.4 8.7 0.0 4.9 5 2 2 7 7 7 0 Leucine rich repeat Glyco_hydro_35 PF01301.14 KEY69709.1 - 1.5e-81 274.2 1.0 8.1e-81 271.8 0.7 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 KEY69709.1 - 2.4e-59 199.7 0.2 4.4e-59 198.9 0.2 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 KEY69709.1 - 1e-40 138.4 0.9 3.5e-20 72.3 0.2 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 KEY69709.1 - 2.1e-17 62.2 0.0 1.1e-16 59.9 0.0 2.2 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 KEY69709.1 - 3.7e-07 29.6 0.9 1.2e-06 27.9 0.1 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) F-box PF00646.28 KEY69712.1 - 2e-09 36.8 0.1 4.6e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KEY69712.1 - 4e-05 23.2 0.0 0.0001 21.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 KEY69712.1 - 0.016 15.1 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 PRANC domain 7TM_GPCR_Srb PF02175.11 KEY69712.1 - 0.031 13.8 0.2 0.066 12.7 0.1 1.5 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srb Cript PF10235.4 KEY69712.1 - 0.19 12.0 2.1 0.49 10.7 0.2 2.2 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT DUF4117 PF13491.1 KEY69712.1 - 0.47 9.8 4.9 0.26 10.7 1.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4117) CarbpepA_inh PF02977.10 KEY69712.1 - 4.8 6.8 9.0 0.4 10.2 1.5 2.3 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor Abhydrolase_6 PF12697.2 KEY69713.1 - 2.1e-26 93.2 0.5 3.8e-26 92.3 0.4 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY69713.1 - 3.3e-11 43.2 0.0 1.2e-10 41.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY69713.1 - 9.2e-08 31.9 0.0 2.1e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KEY69713.1 - 1.2e-05 23.9 0.0 5.3e-05 21.8 0.0 2.0 1 1 0 1 1 1 1 Ndr family EthD PF07110.6 KEY69713.1 - 2.4e-05 25.1 0.7 0.014 16.3 0.0 2.9 2 0 0 2 2 2 2 EthD domain Esterase PF00756.15 KEY69713.1 - 0.00013 21.5 0.0 0.00022 20.7 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DUF4286 PF14114.1 KEY69713.1 - 0.13 12.5 0.0 6.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) Zn_clus PF00172.13 KEY69714.1 - 5e-06 26.3 8.5 8.2e-06 25.6 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M20 PF01546.23 KEY69717.1 - 0.0012 18.3 0.8 0.0018 17.8 0.5 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Polyketide_cyc2 PF10604.4 KEY69717.1 - 0.12 12.5 0.4 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport E1-E2_ATPase PF00122.15 KEY69719.1 - 5.2e-64 215.4 3.7 5.2e-64 215.4 2.6 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KEY69719.1 - 2.5e-29 103.2 0.0 1.3e-27 97.6 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 KEY69719.1 - 6.3e-25 87.7 7.2 6.3e-25 87.7 5.0 3.0 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.21 KEY69719.1 - 3.3e-16 58.4 0.0 1.2e-15 56.6 0.0 2.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KEY69719.1 - 1.9e-15 56.5 0.0 5.7e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEY69719.1 - 1.3e-11 45.0 0.0 3.1e-11 43.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEY69719.1 - 0.0017 18.0 0.2 0.0058 16.2 0.2 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.5 KEY69719.1 - 0.0057 16.2 1.7 0.013 15.0 1.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) PI3K_C2 PF00792.19 KEY69719.1 - 0.064 13.0 0.0 0.42 10.3 0.0 2.0 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 ITAM_Cys-rich PF10538.4 KEY69719.1 - 0.094 12.2 0.3 0.18 11.3 0.2 1.5 1 0 0 1 1 1 0 Immunoreceptor tyrosine-based activation motif FAD_binding_3 PF01494.14 KEY69720.1 - 1.3e-14 54.0 0.0 9.9e-14 51.1 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEY69720.1 - 0.0001 21.3 0.1 0.0017 17.3 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEY69720.1 - 0.00023 21.5 0.0 0.0054 17.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KEY69720.1 - 0.003 16.9 0.1 0.0084 15.5 0.1 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.1 KEY69720.1 - 0.0062 16.5 0.3 0.016 15.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEY69720.1 - 0.011 14.5 1.2 0.018 13.8 0.8 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 KEY69720.1 - 0.076 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.4 KEY69720.1 - 0.094 12.4 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain Pyr_redox_2 PF07992.9 KEY69720.1 - 0.11 12.3 0.1 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SHNi-TPR PF10516.4 KEY69720.1 - 0.16 11.2 0.0 0.35 10.1 0.0 1.6 1 0 0 1 1 1 0 SHNi-TPR KGG PF10685.4 KEY69721.1 - 1.5e-26 91.7 20.4 8.9e-12 44.6 1.7 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif Hemerythrin PF01814.18 KEY69722.1 - 1.1e-10 41.8 1.2 1.1e-10 41.8 0.9 1.7 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain Med3 PF11593.3 KEY69723.1 - 0.45 9.6 2.2 0.58 9.3 1.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ank_2 PF12796.2 KEY69724.1 - 1.1e-18 67.3 2.4 4.2e-13 49.4 0.5 3.5 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEY69724.1 - 1.4e-18 66.8 5.7 6.3e-05 23.3 0.1 7.2 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.25 KEY69724.1 - 5e-15 54.4 7.9 2.4e-06 27.0 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 KEY69724.1 - 1e-13 50.9 6.6 2.2e-06 27.7 0.1 4.9 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY69724.1 - 3.8e-13 48.2 5.7 0.00015 21.6 0.0 7.2 7 0 0 7 7 7 3 Ankyrin repeat Mito_carr PF00153.22 KEY69727.1 - 1.1e-45 153.1 8.5 6.2e-17 61.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FMO-like PF00743.14 KEY69728.1 - 1.3e-32 112.7 0.0 4.1e-19 68.1 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KEY69728.1 - 1.7e-14 54.3 0.0 4.2e-14 53.0 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEY69728.1 - 4.7e-07 29.0 0.0 4.3e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KEY69728.1 - 0.00011 22.0 0.0 0.0018 18.0 0.0 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KEY69728.1 - 0.00017 21.5 0.0 0.00093 19.1 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY69728.1 - 0.0097 15.9 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.11 KEY69731.1 - 2.5e-15 56.0 32.4 2.5e-15 56.0 22.4 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY69731.1 - 6e-05 21.7 7.1 6e-05 21.7 4.9 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter DUF3938 PF13074.1 KEY69731.1 - 0.022 14.6 0.7 0.079 12.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) DUF1049 PF06305.6 KEY69731.1 - 0.37 10.3 0.1 0.37 10.3 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) SDA1 PF05285.7 KEY69732.1 - 9.1e-87 291.3 43.5 2.1e-86 290.1 24.4 2.7 3 0 0 3 3 3 2 SDA1 NUC130_3NT PF08158.7 KEY69732.1 - 7.2e-21 74.2 1.8 9.7e-21 73.8 0.1 2.2 3 0 0 3 3 3 1 NUC130/3NT domain Gcd10p PF04189.8 KEY69733.1 - 4.7e-69 232.8 0.0 6.3e-69 232.3 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family P21-Arc PF04062.9 KEY69734.1 - 2e-81 271.9 0.0 2.2e-81 271.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Hormone_3 PF00159.13 KEY69734.1 - 0.052 13.5 0.9 0.12 12.3 0.6 1.5 1 0 0 1 1 1 0 Pancreatic hormone peptide NmrA PF05368.8 KEY69736.1 - 2.1e-75 252.9 0.0 2.6e-75 252.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY69736.1 - 0.00063 19.7 0.1 0.063 13.2 0.1 2.3 1 1 0 1 1 1 1 NADH(P)-binding Fungal_trans PF04082.13 KEY69737.1 - 2.8e-10 39.5 0.1 4.5e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY69737.1 - 2.1e-05 24.3 10.5 3.5e-05 23.5 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fcf1 PF04900.7 KEY69738.1 - 6.4e-39 132.1 0.2 1.9e-38 130.6 0.0 1.7 2 0 0 2 2 2 1 Fcf1 Rep_fac_C PF08542.6 KEY69739.1 - 1.3e-19 69.9 0.0 2.6e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KEY69739.1 - 8e-12 45.1 0.0 6.8e-10 38.8 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KEY69739.1 - 2.6e-11 43.8 0.0 4.5e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KEY69739.1 - 2.3e-07 30.7 0.0 4.3e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEY69739.1 - 2.3e-06 27.7 0.0 0.0001 22.3 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 KEY69739.1 - 4.8e-06 25.8 0.0 1.2e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KEY69739.1 - 1.1e-05 25.6 0.1 0.023 14.8 0.0 2.7 2 1 1 3 3 2 2 AAA domain Rad17 PF03215.10 KEY69739.1 - 1.1e-05 24.3 0.0 0.0079 14.9 0.0 2.5 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 KEY69739.1 - 0.0001 21.8 0.0 0.024 14.0 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain Viral_helicase1 PF01443.13 KEY69739.1 - 0.00012 21.6 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 KEY69739.1 - 0.00017 21.2 0.0 0.00033 20.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEY69739.1 - 0.0015 18.2 0.0 0.0038 16.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain DEAD PF00270.24 KEY69739.1 - 0.002 17.6 0.1 0.16 11.4 0.0 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_25 PF13481.1 KEY69739.1 - 0.0023 17.3 0.1 0.13 11.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.8 KEY69739.1 - 0.0024 17.3 0.0 0.0039 16.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.16 KEY69739.1 - 0.0032 16.6 0.0 0.029 13.5 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI ArgK PF03308.11 KEY69739.1 - 0.0035 16.1 0.0 0.007 15.1 0.0 1.5 1 0 0 1 1 1 1 ArgK protein NTPase_1 PF03266.10 KEY69739.1 - 0.0046 16.6 0.1 0.024 14.3 0.1 2.1 1 1 1 2 2 2 1 NTPase KTI12 PF08433.5 KEY69739.1 - 0.0053 16.0 0.0 0.0093 15.1 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 FtsK_SpoIIIE PF01580.13 KEY69739.1 - 0.008 15.6 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_11 PF13086.1 KEY69739.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KEY69739.1 - 0.017 14.8 0.0 0.06 13.0 0.0 2.0 3 0 0 3 3 1 0 AAA domain (dynein-related subfamily) AAA_31 PF13614.1 KEY69739.1 - 0.019 14.9 0.0 0.058 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain DNA_pol3_gamma3 PF12169.3 KEY69739.1 - 0.025 14.3 0.2 0.72 9.5 0.0 2.8 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III AAA_18 PF13238.1 KEY69739.1 - 0.031 14.5 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MipZ PF09140.6 KEY69739.1 - 0.1 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ DER1 PF04511.10 KEY69741.1 - 4.4e-25 88.3 3.7 5.1e-25 88.1 2.5 1.0 1 0 0 1 1 1 1 Der1-like family SKG6 PF08693.5 KEY69742.1 - 0.0077 15.5 0.6 0.017 14.4 0.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CD99L2 PF12301.3 KEY69742.1 - 0.012 15.2 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 CD99 antigen like protein 2 DUF1049 PF06305.6 KEY69742.1 - 2.9 7.4 6.9 0.15 11.5 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) CN_hydrolase PF00795.17 KEY69743.1 - 5.9e-13 48.5 0.0 1e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Cpl-7 PF08230.6 KEY69743.1 - 0.11 12.2 0.1 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Cpl-7 lysozyme C-terminal domain Tetraspannin PF00335.15 KEY69744.1 - 0.029 13.6 0.2 0.029 13.6 0.1 2.0 2 0 0 2 2 2 0 Tetraspanin family DKCLD PF08068.7 KEY69745.1 - 9e-31 105.5 0.1 7e-30 102.7 0.1 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 KEY69745.1 - 8.2e-23 81.2 4.7 9.7e-17 61.5 0.1 3.5 2 1 1 3 3 3 2 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 KEY69745.1 - 6.4e-21 73.8 0.4 1.4e-20 72.7 0.3 1.6 1 0 0 1 1 1 1 PUA domain Med19 PF10278.4 KEY69745.1 - 1 8.9 8.2 2.3 7.8 5.7 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RR_TM4-6 PF06459.7 KEY69745.1 - 7.6 6.3 8.5 11 5.7 5.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyco_hydro_43 PF04616.9 KEY69746.1 - 1.2e-25 90.1 0.0 1.7e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1191 PF06697.7 KEY69747.1 - 0.11 11.2 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) SAC3_GANP PF03399.11 KEY69748.1 - 7.5e-40 136.6 0.0 1.6e-39 135.6 0.0 1.5 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family LTV PF04180.9 KEY69749.1 - 9.5e-106 354.8 13.3 1.1e-105 354.5 9.2 1.0 1 0 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.18 KEY69750.1 - 3.3e-17 62.5 1.0 1.7e-15 57.0 0.0 2.7 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEY69750.1 - 1.9e-08 33.7 0.1 1.3e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 KEY69750.1 - 8.5e-05 21.7 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KEY69750.1 - 0.00041 20.1 0.3 0.038 13.8 0.1 2.6 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.11 KEY69750.1 - 0.0086 15.2 0.1 0.015 14.4 0.1 1.3 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 KEY69750.1 - 0.036 14.5 0.1 0.086 13.3 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Glyco_trans_2_3 PF13632.1 KEY69751.1 - 7.4e-47 159.5 3.6 7.4e-47 159.5 2.5 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KEY69751.1 - 4.9e-09 36.3 0.0 3.1e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KEY69751.1 - 0.057 13.1 0.0 0.46 10.1 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_hydro_16 PF00722.16 KEY69752.1 - 6.9e-21 74.3 0.8 1.2e-20 73.5 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF2957 PF11170.3 KEY69752.1 - 0.054 12.1 0.0 0.086 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2957) GAS2 PF02187.12 KEY69753.1 - 4.8e-05 23.0 0.0 9.8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Fungal_trans PF04082.13 KEY69754.1 - 8.2e-37 126.4 0.4 8.2e-37 126.4 0.3 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY69754.1 - 4e-08 33.0 9.6 8e-08 32.0 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OMP_b-brl PF13505.1 KEY69754.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain Malic_M PF03949.10 KEY69755.1 - 2.6e-86 289.3 0.0 3.9e-86 288.7 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KEY69755.1 - 1e-71 240.2 0.0 1.7e-71 239.5 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Cytadhesin_P30 PF07271.6 KEY69756.1 - 3.4 6.8 6.9 3.9 6.6 4.8 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 POT1 PF02765.12 KEY69757.1 - 2.9e-10 40.2 0.0 4.6e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 FMO-like PF00743.14 KEY69758.1 - 2.4e-35 121.7 0.0 1.9e-16 59.3 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KEY69758.1 - 1.8e-15 57.5 0.0 7.1e-15 55.6 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEY69758.1 - 5.8e-12 45.1 0.1 3.1e-09 36.2 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KEY69758.1 - 3e-11 43.3 0.0 3.1e-10 40.0 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KEY69758.1 - 2.4e-10 40.6 0.0 1.5e-09 38.0 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY69758.1 - 6.9e-08 32.4 0.0 2.8e-07 30.4 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KEY69758.1 - 4.5e-07 29.1 0.0 4.6e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KEY69758.1 - 8.4e-05 21.6 0.0 0.065 12.1 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KEY69758.1 - 0.00034 19.2 0.2 0.074 11.5 0.0 2.9 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.19 KEY69758.1 - 0.0015 17.7 0.0 0.098 11.7 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KEY69758.1 - 0.0048 15.8 0.0 0.63 8.8 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 KEY69758.1 - 0.0053 17.1 0.0 1.1 9.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEY69758.1 - 0.015 14.3 0.1 0.11 11.4 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.15 KEY69758.1 - 0.018 15.1 0.0 0.52 10.4 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase MAF_flag10 PF01973.13 KEY69758.1 - 0.051 13.0 0.1 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF115 Semialdhyde_dh PF01118.19 KEY69758.1 - 0.061 13.6 0.0 6.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KEY69758.1 - 0.062 12.1 0.0 0.94 8.2 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.13 KEY69758.1 - 0.098 12.6 0.3 0.33 10.9 0.0 2.0 3 0 0 3 3 2 0 TrkA-N domain Aminotran_1_2 PF00155.16 KEY69759.1 - 2.3e-09 36.7 0.0 4.1e-08 32.5 0.0 2.3 2 1 0 2 2 2 1 Aminotransferase class I and II Tannase PF07519.6 KEY69759.1 - 0.2 10.3 0.0 0.32 9.6 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase Ribosomal_L4 PF00573.17 KEY69760.1 - 3e-41 140.9 0.1 4.1e-41 140.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KEY69760.1 - 1.3e-25 89.0 3.2 1.5e-25 88.8 1.2 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain PGA2 PF07543.7 KEY69762.1 - 2e-35 121.6 4.3 2.5e-35 121.3 3.0 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 DUF1301 PF06979.7 KEY69762.1 - 0.011 15.8 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1301) U79_P34 PF03064.11 KEY69762.1 - 0.71 9.3 10.7 0.97 8.8 7.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 GTP_EFTU PF00009.22 KEY69763.1 - 7.7e-60 201.5 0.2 1e-59 201.1 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KEY69763.1 - 2.6e-24 85.2 0.0 5.6e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KEY69763.1 - 1.4e-16 60.3 2.6 1.4e-16 60.3 1.8 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEY69763.1 - 7.7e-06 25.8 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 KEY69763.1 - 0.00016 21.2 0.4 0.00045 19.8 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 KEY69763.1 - 0.0007 20.0 0.0 0.0014 19.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 KEY69763.1 - 0.077 12.4 0.1 9.8 5.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_S14 PF00253.16 KEY69764.1 - 4.4e-18 64.3 2.8 4.8e-18 64.2 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 KEY69764.1 - 0.068 12.9 0.7 0.076 12.7 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) DUF1451 PF07295.6 KEY69764.1 - 0.11 12.2 0.2 0.11 12.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) ZZ PF00569.12 KEY69764.1 - 0.54 9.8 3.7 2.9 7.4 2.6 1.9 1 1 0 1 1 1 0 Zinc finger, ZZ type Thioredoxin PF00085.15 KEY69765.1 - 2e-62 207.3 0.1 4.3e-30 103.4 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 KEY69765.1 - 1.3e-22 80.2 0.1 6.9e-22 77.8 0.0 2.2 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 KEY69765.1 - 1.8e-19 69.9 0.1 8.6e-09 35.5 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KEY69765.1 - 3.6e-14 52.5 0.0 1e-06 28.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 KEY69765.1 - 8.8e-14 51.3 0.1 1.9e-05 24.6 0.0 3.6 3 1 1 4 4 3 2 Thioredoxin-like AhpC-TSA PF00578.16 KEY69765.1 - 5.3e-08 32.5 0.2 0.016 14.8 0.0 2.8 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 KEY69765.1 - 9.5e-07 28.4 0.4 0.018 14.5 0.0 2.5 2 0 0 2 2 2 2 Redoxin Thioredoxin_6 PF13848.1 KEY69765.1 - 1.1e-05 25.3 0.1 0.15 11.8 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_4 PF13462.1 KEY69765.1 - 1.9e-05 24.7 0.2 0.35 10.8 0.0 3.2 2 2 1 3 3 3 2 Thioredoxin ERp29_N PF07912.8 KEY69765.1 - 2.3e-05 24.3 0.1 0.0014 18.5 0.0 2.4 2 0 0 2 2 2 1 ERp29, N-terminal domain Thioredoxin_3 PF13192.1 KEY69765.1 - 2.7e-05 23.9 0.0 0.32 10.8 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_9 PF14595.1 KEY69765.1 - 0.00024 20.6 0.0 0.19 11.2 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Glutaredoxin PF00462.19 KEY69765.1 - 0.0028 17.5 0.1 3.3 7.7 0.1 3.0 2 1 0 2 2 2 2 Glutaredoxin HyaE PF07449.6 KEY69765.1 - 0.028 14.3 0.0 0.22 11.4 0.0 2.3 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE HsbA PF12296.3 KEY69765.1 - 0.23 11.3 3.3 0.2 11.5 0.3 2.2 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Mu-like_Com PF10122.4 KEY69765.1 - 0.33 10.0 1.0 8.3 5.5 0.1 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com HSBP1 PF06825.7 KEY69766.1 - 4.3e-16 58.2 0.0 5e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 KEY69766.1 - 0.0047 16.2 0.2 0.6 9.5 0.1 2.2 1 1 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin Baculo_PEP_C PF04513.7 KEY69766.1 - 0.0055 16.5 0.1 0.0059 16.4 0.1 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Thiol_cytolysin PF01289.14 KEY69766.1 - 0.032 12.6 0.1 0.032 12.5 0.1 1.0 1 0 0 1 1 1 0 Thiol-activated cytolysin UBN2 PF14223.1 KEY69766.1 - 0.066 13.0 0.0 0.076 12.7 0.0 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Erythro-docking PF09277.6 KEY69766.1 - 0.13 11.9 0.3 7 6.4 0.1 2.2 1 1 1 2 2 2 0 Erythronolide synthase, docking AATF-Che1 PF13339.1 KEY69766.1 - 0.32 11.1 2.0 4.3 7.4 1.4 2.0 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor zf-rbx1 PF12678.2 KEY69767.1 - 1.7e-09 37.6 0.9 3.3e-09 36.7 0.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KEY69767.1 - 2.2e-08 33.7 7.2 7.4e-08 32.0 5.0 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KEY69767.1 - 2.1e-07 30.4 2.1 3.5e-07 29.7 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY69767.1 - 2.2e-07 30.4 2.3 4.8e-07 29.3 1.6 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KEY69767.1 - 7.2e-06 25.5 4.8 3.1e-05 23.5 3.4 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEY69767.1 - 3.5e-05 23.7 2.8 3.5e-05 23.7 1.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEY69767.1 - 0.003 17.3 0.6 0.0089 15.8 0.4 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KEY69767.1 - 0.011 15.3 3.1 0.026 14.2 1.2 2.4 1 1 0 1 1 1 0 RING-type zinc-finger Myc_target_1 PF15179.1 KEY69767.1 - 0.025 14.1 0.8 0.054 13.0 0.6 1.5 1 0 0 1 1 1 0 Myc target protein 1 zf-RING_6 PF14835.1 KEY69767.1 - 0.17 11.6 1.2 1.4 8.7 0.8 2.2 1 1 0 1 1 1 0 zf-RING of BARD1-type protein DUF2921 PF11145.3 KEY69767.1 - 0.26 8.9 0.3 0.38 8.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) FANCL_C PF11793.3 KEY69767.1 - 1.2 9.1 5.1 3.6 7.6 3.6 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_clus PF00172.13 KEY69768.1 - 1.1e-08 34.7 8.7 1.9e-08 34.0 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEY69768.1 - 0.017 13.7 0.4 0.073 11.6 0.1 1.9 2 0 0 2 2 2 0 Fungal specific transcription factor domain DUF2719 PF10891.3 KEY69768.1 - 0.099 12.3 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2719) Rhomboid PF01694.17 KEY69771.1 - 1.1e-33 116.2 9.6 1.1e-33 116.2 6.7 1.8 2 0 0 2 2 2 1 Rhomboid family DNA_pol_B PF00136.16 KEY69772.1 - 1.7e-142 475.4 2.9 2.9e-142 474.7 2.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KEY69772.1 - 3.1e-77 259.6 0.5 5.4e-77 258.8 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KEY69772.1 - 1.2e-23 82.8 4.9 3.3e-23 81.4 3.4 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 KEY69772.1 - 0.00011 22.0 0.1 0.00046 20.0 0.1 2.1 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 KEY69772.1 - 0.0015 18.0 0.0 0.0031 17.0 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.8 KEY69772.1 - 0.007 15.0 0.0 0.007 15.0 0.0 2.4 3 0 0 3 3 3 1 DNA polymerase type B, organellar and viral ELFV_dehydrog PF00208.16 KEY69773.1 - 1e-83 280.6 3.7 1.3e-83 280.3 2.5 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KEY69773.1 - 1.6e-49 166.8 0.0 3.4e-49 165.7 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 KEY69773.1 - 0.02 15.1 0.1 0.046 13.9 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 KEY69773.1 - 0.094 12.2 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CoA_transf_3 PF02515.12 KEY69774.1 - 3.1e-52 176.5 0.2 3.1e-52 176.5 0.2 2.0 2 0 0 2 2 2 1 CoA-transferase family III Dynamin_M PF01031.15 KEY69775.1 - 2.7e-106 354.6 0.3 9e-106 352.9 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KEY69775.1 - 2e-56 190.4 0.0 4.3e-56 189.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KEY69775.1 - 4.3e-29 100.2 6.1 4.3e-29 100.2 4.3 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KEY69775.1 - 0.00011 22.0 0.8 0.0016 18.4 0.1 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KEY69775.1 - 0.0079 16.6 0.0 0.03 14.8 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein RTA1 PF04479.8 KEY69776.1 - 2.7e-44 151.3 0.2 2.7e-44 151.3 0.1 1.3 2 0 0 2 2 2 1 RTA1 like protein DUF2244 PF10003.4 KEY69776.1 - 6.4 6.1 8.2 9.3 5.6 1.5 2.8 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) Exotox-A_bind PF09101.5 KEY69777.1 - 0.064 12.3 0.0 0.076 12.1 0.0 1.1 1 0 0 1 1 1 0 Exotoxin A binding Peroxidase_2 PF01328.12 KEY69778.1 - 3.6e-31 108.0 0.6 4.5e-31 107.7 0.4 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Fungal_trans_2 PF11951.3 KEY69779.1 - 9e-10 37.6 0.7 1.2e-09 37.2 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FA_hydroxylase PF04116.8 KEY69779.1 - 0.47 10.8 6.7 0.048 14.0 0.8 2.2 3 0 0 3 3 3 0 Fatty acid hydroxylase superfamily WD40 PF00400.27 KEY69780.1 - 3.1e-25 87.0 8.8 7.4e-07 28.8 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat CLTH PF10607.4 KEY69780.1 - 0.021 14.5 0.2 0.036 13.7 0.1 1.4 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain eIF2A PF08662.6 KEY69780.1 - 0.22 11.2 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A CAS_CSE1 PF03378.10 KEY69782.1 - 1.3e-149 498.2 0.1 1.4e-148 494.8 0.0 2.3 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 KEY69782.1 - 9e-147 488.4 8.1 1.2e-146 488.0 5.6 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 KEY69782.1 - 4.5e-11 42.5 0.3 1.6e-10 40.7 0.1 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KEY69782.1 - 0.008 16.0 2.2 0.94 9.3 0.0 4.2 3 2 0 3 3 3 1 Exportin 1-like protein HEAT_2 PF13646.1 KEY69782.1 - 0.02 15.1 0.9 0.65 10.3 0.0 3.6 4 1 0 4 4 4 0 HEAT repeats YhdB PF14148.1 KEY69782.1 - 0.027 14.2 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 YhdB-like protein DUF2785 PF10978.3 KEY69782.1 - 0.058 12.8 0.1 15 4.9 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2785) DUF3384 PF11864.3 KEY69783.1 - 8.6e-93 311.3 0.0 1.7e-92 310.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 KEY69783.1 - 2.2e-53 180.4 0.0 6.4e-53 178.9 0.0 1.8 2 0 0 2 2 2 1 Rap/ran-GAP Tuberin PF03542.11 KEY69783.1 - 1.3e-29 103.4 0.7 1.4e-26 93.3 0.0 2.5 2 0 0 2 2 2 2 Tuberin Acetyltransf_1 PF00583.19 KEY69785.1 - 5.3e-05 23.1 0.1 0.00019 21.3 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KEY69785.1 - 0.00012 22.2 0.0 0.00092 19.3 0.0 2.4 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KEY69785.1 - 0.01 15.7 0.0 0.032 14.1 0.0 1.8 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 KEY69785.1 - 0.045 13.9 0.1 0.26 11.4 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEY69785.1 - 0.076 12.7 0.5 0.43 10.3 0.0 2.4 2 0 0 2 2 2 0 FR47-like protein CENP-I PF07778.6 KEY69786.1 - 8.4e-103 344.2 1.3 1.7e-102 343.2 0.5 1.7 2 0 0 2 2 2 1 Mis6 ABC_tran PF00005.22 KEY69787.1 - 2.3e-15 57.0 0.0 1.2e-14 54.7 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KEY69787.1 - 4.1e-10 40.1 0.0 0.00041 20.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KEY69787.1 - 0.00015 20.9 0.0 0.16 11.0 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain DUF3584 PF12128.3 KEY69787.1 - 0.00047 17.6 0.1 0.00062 17.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_29 PF13555.1 KEY69787.1 - 0.00053 19.4 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 KEY69787.1 - 0.0014 17.9 0.0 0.89 8.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.4 KEY69787.1 - 0.0014 18.0 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 KEY69787.1 - 0.0019 18.9 0.3 0.0064 17.2 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEY69787.1 - 0.004 16.5 0.2 0.0074 15.7 0.2 1.7 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 KEY69787.1 - 0.0059 16.0 0.0 0.0091 15.4 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_23 PF13476.1 KEY69787.1 - 0.0083 16.4 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 KEY69787.1 - 0.0092 15.4 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.1 KEY69787.1 - 0.014 15.3 1.3 0.046 13.6 0.9 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 KEY69787.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KEY69787.1 - 0.024 14.7 0.4 0.13 12.3 0.2 2.2 1 1 1 2 2 2 0 AAA domain AAA_10 PF12846.2 KEY69787.1 - 0.026 13.9 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.24 KEY69787.1 - 0.03 14.5 0.1 0.16 12.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KEY69787.1 - 0.036 13.9 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KEY69787.1 - 0.058 12.5 0.0 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 KEY69787.1 - 0.11 12.3 0.1 0.28 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KEY69787.1 - 0.11 12.1 0.1 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_13 PF13166.1 KEY69787.1 - 0.13 10.7 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 KEY69787.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family cobW PF02492.14 KEY69787.1 - 0.14 11.5 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 KEY69787.1 - 0.16 11.7 0.3 0.98 9.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KEY69787.1 - 0.19 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin DNA_pol_E_B PF04042.11 KEY69788.1 - 5.5e-51 172.7 0.0 7.2e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CAP_N PF01213.14 KEY69789.1 - 4.8 6.3 8.3 9.9 5.3 5.7 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PALP PF00291.20 KEY69790.1 - 3.1e-52 177.6 1.0 3.8e-52 177.4 0.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1181 PF06680.6 KEY69790.1 - 0.044 13.4 0.1 0.093 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1181) CENP-S PF15630.1 KEY69791.1 - 5e-35 119.5 0.1 7.3e-35 119.0 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 KEY69791.1 - 0.001 18.7 0.0 0.0017 18.0 0.0 1.4 1 1 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 KEY69791.1 - 0.0022 17.3 0.0 0.003 16.8 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T TFIID-18kDa PF02269.11 KEY69791.1 - 0.013 15.3 0.1 0.015 15.0 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit TFIID-31kDa PF02291.10 KEY69791.1 - 0.072 12.8 0.1 0.083 12.6 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit WSC PF01822.14 KEY69792.1 - 3e-46 155.2 40.5 3.4e-18 65.3 7.6 3.8 3 0 0 3 3 3 3 WSC domain peroxidase PF00141.18 KEY69792.1 - 1.2e-19 70.7 0.0 2.4e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Peroxidase MARVEL PF01284.18 KEY69793.1 - 4.8e-07 29.6 12.3 7.3e-07 29.1 8.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.7 KEY69793.1 - 0.013 15.0 9.9 0.013 15.0 6.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF588) Tetraspannin PF00335.15 KEY69793.1 - 1.4 8.1 7.8 1.1 8.4 4.5 1.4 1 1 0 1 1 1 0 Tetraspanin family DUF3402 PF11882.3 KEY69794.1 - 9.7e-154 512.3 0.0 1.3e-153 511.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 KEY69794.1 - 1.4e-72 244.0 0.0 1.9e-72 243.5 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein CDC45 PF02724.9 KEY69794.1 - 0.042 11.8 0.0 0.06 11.3 0.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2011 PF09428.5 KEY69795.1 - 1.7e-24 86.2 18.1 3.6e-24 85.1 12.6 1.6 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2011) NDT80_PhoG PF05224.7 KEY69796.1 - 1.9e-32 112.7 0.0 3.5e-32 111.9 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family RWD PF05773.17 KEY69797.1 - 1.5e-20 73.1 0.0 2.3e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 KEY69797.1 - 1.2e-19 69.9 31.2 2.3e-13 49.8 0.5 3.9 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 KEY69797.1 - 0.0002 21.1 7.5 0.0002 21.1 5.2 3.5 2 1 1 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 KEY69797.1 - 0.0035 17.0 5.1 0.0035 17.0 3.6 3.9 2 1 2 4 4 4 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KEY69797.1 - 0.016 15.1 1.8 0.016 15.1 1.2 4.2 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KEY69797.1 - 3 7.5 35.4 0.032 13.8 5.6 4.0 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) PAP2 PF01569.16 KEY69798.1 - 9.1e-15 54.4 8.0 1.1e-14 54.2 5.0 1.6 1 1 0 1 1 1 1 PAP2 superfamily BPD_transp_2 PF02653.11 KEY69798.1 - 0.00027 20.0 1.2 0.096 11.6 0.0 2.2 2 0 0 2 2 2 2 Branched-chain amino acid transport system / permease component DUF212 PF02681.9 KEY69798.1 - 0.053 13.2 0.0 0.42 10.3 0.0 2.2 2 0 0 2 2 2 0 Divergent PAP2 family DUF2823 PF11034.3 KEY69800.1 - 1.7e-31 108.1 10.6 1.8e-31 108.0 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) EBP PF05241.7 KEY69801.1 - 5e-67 224.6 3.4 6.1e-67 224.4 2.4 1.0 1 0 0 1 1 1 1 Emopamil binding protein NAD_kinase PF01513.16 KEY69802.1 - 4.8e-69 232.2 0.0 7.3e-69 231.6 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase IF3_C PF00707.17 KEY69802.1 - 0.028 14.1 0.1 0.087 12.5 0.1 1.9 1 0 0 1 1 1 0 Translation initiation factor IF-3, C-terminal domain FHA PF00498.21 KEY69803.1 - 0.057 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 FHA domain NAD_binding_10 PF13460.1 KEY69807.1 - 2.3e-14 53.7 0.0 3.3e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEY69807.1 - 1.3e-10 41.1 0.0 3.6e-10 39.6 0.0 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Glyco_transf_4 PF13439.1 KEY69807.1 - 0.081 12.6 0.0 0.7 9.5 0.0 2.1 2 1 0 2 2 2 0 Glycosyltransferase Family 4 Glyco_hydro_6 PF01341.12 KEY69808.1 - 2.4e-82 276.7 0.0 2.9e-82 276.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Sugar_tr PF00083.19 KEY69809.1 - 1.9e-69 234.4 23.3 2.2e-69 234.2 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY69809.1 - 2.1e-18 66.1 26.9 2.1e-18 66.1 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidoligase_2 PF12224.3 KEY69811.1 - 1.7e-11 44.2 0.0 2.9e-08 33.6 0.0 2.4 2 1 0 2 2 2 2 Putative amidoligase enzyme p450 PF00067.17 KEY69812.1 - 5.2e-39 134.0 0.0 7.8e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 KEY69813.1 - 9.5e-07 28.6 10.8 2e-06 27.6 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Siva PF05458.7 KEY69813.1 - 0.24 10.9 4.7 0.42 10.1 3.3 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) CLN3 PF02487.12 KEY69814.1 - 3.8e-28 98.3 3.8 4.7e-28 98.0 2.6 1.0 1 0 0 1 1 1 1 CLN3 protein DUF805 PF05656.9 KEY69815.1 - 0.029 14.2 0.1 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF805) WD40 PF00400.27 KEY69817.1 - 2.8e-13 49.1 8.2 1.7e-05 24.5 0.2 4.8 6 0 0 6 6 6 2 WD domain, G-beta repeat PQQ_3 PF13570.1 KEY69817.1 - 0.091 13.0 0.0 1.8 8.9 0.0 3.0 3 1 0 3 3 3 0 PQQ-like domain Complex1_LYR_1 PF13232.1 KEY69818.1 - 1.6e-20 73.0 4.0 2.1e-20 72.6 2.8 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KEY69818.1 - 3e-19 68.5 4.3 4.1e-19 68.1 3.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 KEY69818.1 - 0.0054 17.1 0.5 0.0058 17.0 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like IL28A PF15177.1 KEY69818.1 - 0.019 14.4 0.2 0.024 14.1 0.1 1.1 1 0 0 1 1 1 0 Interleukin-28A DUF1469 PF07332.6 KEY69820.1 - 6.3 6.5 16.8 0.63 9.7 1.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Fasciclin PF02469.17 KEY69821.1 - 9.2e-45 151.7 0.4 1e-24 86.9 0.1 2.1 2 0 0 2 2 2 2 Fasciclin domain FLgD_tudor PF13861.1 KEY69821.1 - 0.41 10.6 3.4 0.78 9.7 0.4 3.0 2 1 0 2 2 2 0 FlgD Tudor-like domain RNase_T PF00929.19 KEY69822.1 - 2.3e-13 50.7 0.0 8.6e-13 48.8 0.0 1.9 1 1 0 1 1 1 1 Exonuclease Methyltransf_23 PF13489.1 KEY69823.1 - 1.1e-23 83.7 0.0 1.7e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY69823.1 - 3e-12 47.1 0.0 2.7e-11 44.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY69823.1 - 3.4e-11 42.9 0.0 1.9e-10 40.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY69823.1 - 6.4e-10 39.3 0.0 1.5e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY69823.1 - 3.5e-08 33.8 0.0 1.9e-07 31.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY69823.1 - 7.5e-05 22.1 0.0 0.00096 18.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KEY69823.1 - 0.00015 21.8 0.0 0.00039 20.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY69823.1 - 0.00017 21.9 0.0 0.00058 20.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEY69823.1 - 0.00033 19.7 0.0 0.002 17.1 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 KEY69823.1 - 0.0012 17.9 0.0 0.0027 16.8 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 KEY69823.1 - 0.0027 17.7 0.0 0.004 17.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 KEY69823.1 - 0.017 14.2 0.0 0.25 10.4 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 KEY69823.1 - 0.043 13.0 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase PrmA PF06325.8 KEY69823.1 - 0.084 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) p450 PF00067.17 KEY69824.1 - 1.4e-51 175.5 0.0 2.3e-51 174.8 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KEY69827.1 - 3.6e-27 95.0 69.2 7.5e-25 87.3 33.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 KEY69831.1 - 3.9e-29 101.7 0.3 7.8e-29 100.7 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY69831.1 - 1e-17 64.7 0.3 1.7e-17 63.9 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase S-methyl_trans PF02574.11 KEY69831.1 - 1.8e-16 60.3 0.0 3e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Homocysteine S-methyltransferase KR PF08659.5 KEY69831.1 - 1.1e-12 47.9 0.3 2.3e-12 46.9 0.2 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KEY69831.1 - 0.028 14.4 0.0 0.066 13.2 0.0 1.7 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 KEY69831.1 - 0.037 13.4 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DAO PF01266.19 KEY69832.1 - 9.9e-40 136.5 5.7 1.6e-39 135.8 4.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEY69832.1 - 1.4e-05 24.1 0.7 2.1e-05 23.5 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KEY69832.1 - 3.4e-05 23.7 0.1 8e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KEY69832.1 - 9e-05 22.4 0.0 0.061 13.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY69832.1 - 9.2e-05 22.7 0.0 0.12 12.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEY69832.1 - 0.063 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KEY69832.1 - 0.065 12.1 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein CBFD_NFYB_HMF PF00808.18 KEY69833.1 - 6.4e-18 64.5 0.4 8.9e-18 64.1 0.3 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KEY69833.1 - 0.00014 21.8 0.0 0.00019 21.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Decorin_bind PF02352.10 KEY69833.1 - 0.017 15.1 0.3 0.041 13.8 0.2 1.6 1 1 0 1 1 1 0 Decorin binding protein HEAT_PBS PF03130.11 KEY69833.1 - 0.13 12.7 0.0 11 6.7 0.0 2.3 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat Isochorismatase PF00857.15 KEY69834.1 - 8.1e-41 139.8 0.1 9.1e-41 139.6 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family AA_permease PF00324.16 KEY69835.1 - 1.2e-115 386.6 40.7 1.3e-115 386.4 28.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEY69835.1 - 1.8e-27 95.9 48.0 2.4e-27 95.5 33.3 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2263 PF10021.4 KEY69836.1 - 2e-25 89.4 0.0 4e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) BCS1_N PF08740.6 KEY69837.1 - 1.5e-43 148.6 0.0 2e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KEY69837.1 - 3.4e-17 62.8 0.0 5.5e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEY69837.1 - 1.5e-05 25.8 0.0 3e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEY69837.1 - 0.00031 20.2 0.0 0.00097 18.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEY69837.1 - 0.0019 17.9 0.0 0.007 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KEY69837.1 - 0.0019 18.0 0.0 0.0051 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain SLH PF00395.15 KEY69837.1 - 0.0029 17.3 0.0 0.0063 16.2 0.0 1.6 1 0 0 1 1 1 1 S-layer homology domain AAA_29 PF13555.1 KEY69837.1 - 0.0029 17.0 0.0 0.0064 15.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 KEY69837.1 - 0.0046 16.9 0.0 0.0066 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEY69837.1 - 0.0069 16.5 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KEY69837.1 - 0.0079 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter DUF815 PF05673.8 KEY69837.1 - 0.012 14.5 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RuvB_N PF05496.7 KEY69837.1 - 0.016 14.2 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KEY69837.1 - 0.017 15.1 0.0 0.05 13.5 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain Miro PF08477.8 KEY69837.1 - 0.018 15.5 0.0 0.037 14.5 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Zeta_toxin PF06414.7 KEY69837.1 - 0.019 14.0 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 KEY69837.1 - 0.023 14.9 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KEY69837.1 - 0.051 12.7 0.0 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KEY69837.1 - 0.077 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 KEY69837.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AFOR_C PF01314.13 KEY69837.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 ATP_bind_1 PF03029.12 KEY69837.1 - 0.21 11.1 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein F_bP_aldolase PF01116.15 KEY69838.1 - 3.3e-97 325.0 0.0 3.7e-97 324.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II MR_MLE_C PF13378.1 KEY69838.1 - 0.078 12.9 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Enolase C-terminal domain-like Oxysterol_BP PF01237.13 KEY69839.1 - 2.3e-86 289.5 0.0 2.8e-86 289.1 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Cid2 PF09774.4 KEY69840.1 - 5.2e-47 159.7 0.0 6.7e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 NARP1 PF12569.3 KEY69841.1 - 7.2e-195 648.6 22.1 2.4e-193 643.5 12.5 2.3 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.1 KEY69841.1 - 1.6e-21 76.4 21.6 0.00033 20.9 1.4 7.5 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 KEY69841.1 - 7.9e-18 64.6 28.4 0.00054 20.5 0.1 8.7 7 2 2 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 KEY69841.1 - 1.8e-17 62.2 18.0 0.0018 18.7 0.0 10.5 6 4 4 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.1 KEY69841.1 - 2.4e-16 59.1 27.1 6e-06 25.8 0.3 7.9 6 2 2 8 8 8 6 TPR repeat TPR_2 PF07719.12 KEY69841.1 - 9.4e-13 47.0 27.9 0.00089 18.9 0.1 10.3 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 KEY69841.1 - 1.3e-12 47.3 10.7 4.1e-05 23.3 0.1 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEY69841.1 - 1.2e-10 41.1 24.1 0.04 13.8 0.0 8.0 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEY69841.1 - 6.4e-10 38.4 12.0 0.01 15.9 0.0 8.0 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEY69841.1 - 7.5e-08 31.6 24.6 7e-05 22.2 0.1 8.8 9 1 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEY69841.1 - 2.1e-06 27.1 9.9 0.0076 15.9 0.0 6.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 KEY69841.1 - 1e-05 25.5 4.7 0.24 11.9 0.4 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEY69841.1 - 0.0007 19.2 13.4 2.9 7.9 0.0 7.0 5 1 1 6 6 6 1 Tetratricopeptide repeat BTAD PF03704.12 KEY69841.1 - 0.0044 17.3 0.4 0.0044 17.3 0.3 3.5 4 0 0 4 4 3 2 Bacterial transcriptional activator domain TPR_6 PF13174.1 KEY69841.1 - 0.078 13.4 13.8 11 6.7 0.0 7.0 7 0 0 7 7 5 0 Tetratricopeptide repeat RNase_Zc3h12a PF11977.3 KEY69841.1 - 0.08 12.7 0.9 0.2 11.4 0.6 1.6 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain TPR_10 PF13374.1 KEY69841.1 - 8 6.5 16.5 7.9 6.5 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat DAGK_cat PF00781.19 KEY69842.1 - 1.2e-27 95.9 0.0 1.8e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain BTB PF00651.26 KEY69843.1 - 3.1e-08 33.5 0.1 6.7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain SAC3_GANP PF03399.11 KEY69843.1 - 0.00087 18.8 0.1 0.0018 17.9 0.1 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Nucleo_LEF-12 PF06256.6 KEY69843.1 - 0.034 13.9 0.1 0.034 13.9 0.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus LEF-12 protein tRNA_lig_kinase PF08303.6 KEY69843.1 - 0.12 12.2 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 tRNA ligase kinase domain SecE PF00584.15 KEY69845.1 - 4.4e-14 51.7 0.0 4.9e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex SET PF00856.23 KEY69846.1 - 8.6e-21 74.9 0.0 7.4e-20 71.8 0.0 2.4 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 KEY69846.1 - 1.1e-18 67.3 2.3 1.1e-18 67.3 1.6 2.0 2 0 0 2 2 2 1 Pre-SET motif ubiquitin PF00240.18 KEY69847.1 - 0.0021 17.3 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KEY69847.1 - 0.011 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 KEY69847.1 - 0.085 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Adaptin_N PF01602.15 KEY69848.1 - 4.3e-95 319.0 3.6 7.3e-95 318.2 2.5 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.7 KEY69848.1 - 6e-63 210.7 0.7 1.2e-62 209.7 0.5 1.5 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.1 KEY69848.1 - 1.2e-61 206.1 0.0 3.2e-61 204.7 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.1 KEY69848.1 - 4.4e-11 42.9 8.7 7.6e-07 29.3 0.0 4.5 2 1 2 4 4 4 3 HEAT repeats Cnd1 PF12717.2 KEY69848.1 - 4e-07 30.0 4.0 0.00076 19.3 0.0 3.3 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KEY69848.1 - 0.0021 17.9 0.3 3 8.1 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat RE_Alw26IDE PF09665.5 KEY69848.1 - 0.43 9.2 2.8 0.44 9.2 0.8 1.9 2 0 0 2 2 2 0 Type II restriction endonuclease (RE_Alw26IDE) HEAT_EZ PF13513.1 KEY69848.1 - 0.48 10.9 4.7 5.8 7.5 0.0 4.4 5 0 0 5 5 5 0 HEAT-like repeat Mago_nashi PF02792.9 KEY69849.1 - 3.5e-75 250.4 0.2 4.1e-75 250.2 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein Phage_portal_2 PF05136.8 KEY69849.1 - 0.036 12.6 0.0 0.045 12.2 0.0 1.0 1 0 0 1 1 1 0 Phage portal protein, lambda family Vac_ImportDeg PF09783.4 KEY69850.1 - 1.4e-69 233.0 1.2 2.1e-69 232.5 0.8 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein UPF0020 PF01170.13 KEY69851.1 - 4.9e-09 36.0 0.0 1.1e-08 34.9 0.0 1.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 KEY69851.1 - 3.1e-07 30.4 0.0 6e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ribonuc_P_40 PF08584.6 KEY69852.1 - 1.1e-48 165.7 0.0 1.8e-48 164.9 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Ank_5 PF13857.1 KEY69853.1 - 7.3e-11 41.9 0.1 2.2e-08 34.0 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEY69853.1 - 2.2e-08 34.3 0.0 6.8e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KEY69853.1 - 4.2e-05 23.1 0.4 0.00017 21.1 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 KEY69853.1 - 9.8e-05 22.6 0.2 0.00058 20.1 0.1 1.9 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEY69853.1 - 0.00021 21.2 1.0 0.001 19.0 0.3 2.3 2 0 0 2 2 2 1 Ankyrin repeat Sox_C_TAD PF12067.3 KEY69853.1 - 0.043 13.9 0.1 0.061 13.4 0.0 1.2 1 0 0 1 1 1 0 Sox C-terminal transactivation domain RNA_lig_T4_1 PF09511.5 KEY69854.1 - 5.1e-79 264.8 0.0 1e-78 263.8 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.6 KEY69854.1 - 2.1e-72 243.4 0.0 3e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 KEY69854.1 - 6.8e-55 185.4 0.1 1.4e-54 184.4 0.1 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_33 PF13671.1 KEY69854.1 - 0.016 15.1 1.8 0.039 13.8 0.5 2.3 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KEY69854.1 - 0.021 15.6 0.1 0.071 13.9 0.1 2.0 1 0 0 1 1 1 0 AAA domain Tic20 PF09685.5 KEY69855.1 - 2.6e-07 30.5 2.9 3.6e-07 30.1 2.0 1.2 1 0 0 1 1 1 1 Tic20-like protein Ribosomal_L10 PF00466.15 KEY69856.1 - 0.007 16.2 0.1 0.026 14.4 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein L10 AAA PF00004.24 KEY69857.1 - 1e-39 135.7 0.0 2.1e-39 134.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEY69857.1 - 0.0002 21.1 0.1 0.00091 18.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEY69857.1 - 0.00031 20.7 1.6 0.014 15.3 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 KEY69857.1 - 0.00034 19.7 0.0 0.00075 18.6 0.0 1.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KEY69857.1 - 0.00059 19.9 0.6 0.021 14.9 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.9 KEY69857.1 - 0.0014 18.5 0.0 0.01 15.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 KEY69857.1 - 0.0056 15.9 0.2 0.051 12.8 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 KEY69857.1 - 0.0086 15.2 0.0 0.023 13.8 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KEY69857.1 - 0.012 15.4 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KEY69857.1 - 0.014 14.3 0.0 0.028 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 KEY69857.1 - 0.015 14.7 0.3 0.052 12.9 0.1 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.1 KEY69857.1 - 0.016 14.9 0.4 0.048 13.4 0.3 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 KEY69857.1 - 0.05 13.0 1.6 0.37 10.1 0.2 2.3 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 KEY69857.1 - 0.053 13.1 0.1 0.15 11.5 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KEY69857.1 - 0.1 13.4 0.1 0.1 13.4 0.1 2.7 2 2 0 2 2 2 0 AAA domain Herpes_UL25 PF01499.11 KEY69857.1 - 0.12 10.6 0.3 0.18 10.1 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Ish1 PF10281.4 KEY69858.1 - 1.8e-81 267.7 25.1 1.8e-14 53.4 0.1 8.4 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.22 KEY69858.1 - 1e-11 44.0 0.0 0.13 11.7 0.0 7.2 7 0 0 7 7 7 2 SAP domain HeH PF12949.2 KEY69858.1 - 9.3e-09 34.6 0.0 0.39 10.2 0.0 6.0 6 0 0 6 6 6 3 HeH/LEM domain Slx4 PF09494.5 KEY69858.1 - 7.4e-07 28.8 1.8 8.6 6.1 0.1 6.0 7 0 0 7 7 7 2 Slx4 endonuclease Thioredoxin_6 PF13848.1 KEY69858.1 - 0.024 14.4 0.1 22 4.8 0.0 3.6 4 1 1 5 5 5 0 Thioredoxin-like domain SAM_2 PF07647.12 KEY69858.1 - 0.058 13.2 0.3 2.5 8.0 0.0 3.4 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) BOP1NT PF08145.7 KEY69859.1 - 1.2e-104 349.6 1.9 1.7e-104 349.1 1.3 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 KEY69859.1 - 7.9e-31 104.8 0.4 5.4e-13 48.2 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Lipase_GDSL_2 PF13472.1 KEY69860.1 - 3.4e-19 69.6 2.3 5.2e-19 69.0 1.6 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KEY69860.1 - 2.3e-14 53.8 0.8 3e-13 50.1 0.5 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RVT_3 PF13456.1 KEY69862.1 - 1.3e-06 28.1 0.0 5.4e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase-like 6PF2K PF01591.13 KEY69864.1 - 1.6e-55 187.6 0.0 2.2e-55 187.1 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KEY69864.1 - 8.9e-23 81.1 0.2 1.4e-22 80.5 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 KEY69864.1 - 0.0038 18.0 0.0 0.39 11.5 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KEY69864.1 - 0.024 14.4 0.0 0.13 12.0 0.0 2.1 1 1 0 2 2 2 0 AAA domain Porin_3 PF01459.17 KEY69865.1 - 2.8e-81 272.8 0.1 3.2e-81 272.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin UCH_1 PF13423.1 KEY69866.1 - 2.7e-76 256.8 0.0 5.1e-76 255.9 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L5_C PF00673.16 KEY69867.1 - 1.6e-21 75.8 0.0 2.5e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KEY69867.1 - 0.002 17.9 0.1 0.024 14.4 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L5 Fes1 PF08609.5 KEY69868.1 - 1.9e-30 105.2 4.0 8.4e-30 103.1 1.0 2.6 2 1 1 3 3 3 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 KEY69868.1 - 1.2e-07 31.8 1.1 1.1e-06 28.8 0.1 2.3 2 0 0 2 2 2 1 HEAT repeats Arm PF00514.18 KEY69868.1 - 5.8e-07 29.1 0.1 0.012 15.4 0.0 2.6 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KEY69868.1 - 5.1e-06 26.1 0.0 0.067 13.3 0.0 2.7 2 0 0 2 2 2 2 HEAT repeat HEAT_EZ PF13513.1 KEY69868.1 - 8.7e-06 26.0 0.0 0.00032 21.1 0.0 2.9 2 1 1 3 3 3 2 HEAT-like repeat Adaptin_N PF01602.15 KEY69868.1 - 0.0022 16.3 1.3 0.13 10.5 0.1 2.1 1 1 0 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.3 KEY69868.1 - 0.015 15.2 0.7 0.23 11.3 0.0 2.7 3 0 0 3 3 3 0 V-ATPase subunit H Actin PF00022.14 KEY69869.1 - 3.7e-160 532.6 0.0 4.2e-160 532.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KEY69869.1 - 0.037 14.4 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) RF-1 PF00472.15 KEY69870.1 - 1e-25 89.7 1.6 1.4e-25 89.2 1.1 1.1 1 0 0 1 1 1 1 RF-1 domain IZUMO PF15005.1 KEY69870.1 - 0.05 13.6 0.6 0.07 13.1 0.4 1.1 1 0 0 1 1 1 0 Izumo sperm-egg fusion DUF2562 PF10814.3 KEY69870.1 - 0.099 12.5 1.4 0.18 11.7 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2562) DUF3317 PF11779.3 KEY69871.1 - 2.1e-20 71.9 3.9 2.9e-20 71.4 2.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) WD40 PF00400.27 KEY69872.1 - 1.4e-56 186.4 20.2 3.4e-07 29.8 0.0 10.9 12 0 0 12 12 12 9 WD domain, G-beta repeat BBS2_Mid PF14783.1 KEY69872.1 - 0.058 13.1 0.0 17 5.2 0.0 4.3 5 0 0 5 5 5 0 Ciliary BBSome complex subunit 2, middle region MucBP PF06458.7 KEY69872.1 - 0.071 13.7 0.1 0.18 12.4 0.1 1.6 1 0 0 1 1 1 0 MucBP domain Urm1 PF09138.6 KEY69873.1 - 3.8e-31 107.0 0.0 4.9e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 KEY69873.1 - 0.0002 21.7 0.0 0.00028 21.2 0.0 1.2 1 0 0 1 1 1 1 ThiS family zf-H2C2_2 PF13465.1 KEY69874.1 - 8.6e-20 69.9 27.3 1.2e-07 31.6 1.8 4.7 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 KEY69874.1 - 4.4e-17 61.2 28.1 4.9e-05 23.4 1.3 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY69874.1 - 2.4e-11 43.1 26.8 0.0091 16.2 0.6 5.0 5 0 0 5 5 5 4 C2H2-type zinc finger Ogr_Delta PF04606.7 KEY69874.1 - 0.25 11.0 12.2 0.65 9.7 0.6 3.5 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger Zn-ribbon_8 PF09723.5 KEY69874.1 - 5.7 6.9 10.0 9.8 6.2 0.2 4.1 3 1 1 4 4 4 0 Zinc ribbon domain zf-H2C2_5 PF13909.1 KEY69874.1 - 5.7 7.3 11.9 8.6 6.8 0.4 4.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain C1_4 PF07975.7 KEY69874.1 - 8.9 6.3 9.3 29 4.7 4.7 2.7 1 1 1 2 2 2 0 TFIIH C1-like domain Mito_carr PF00153.22 KEY69875.1 - 1.7e-59 197.5 3.3 1.7e-21 75.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2613 PF11021.3 KEY69875.1 - 6.9 6.4 7.5 0.22 11.2 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) RRM_1 PF00076.17 KEY69876.1 - 5e-34 115.7 0.0 1e-15 57.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY69876.1 - 5.4e-21 74.3 0.0 8.9e-12 44.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY69876.1 - 1.8e-15 56.5 0.0 2.5e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 KEY69876.1 - 0.029 13.8 1.3 1.5 8.3 0.1 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain Nup35_RRM_2 PF14605.1 KEY69876.1 - 0.042 13.6 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PAT1 PF09770.4 KEY69876.1 - 2.4 6.3 13.4 3.1 5.9 9.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cohesin_load PF10345.4 KEY69877.1 - 2e-111 373.1 2.5 2.6e-111 372.7 1.7 1.1 1 0 0 1 1 1 1 Cohesin loading factor Transglut_core PF01841.14 KEY69878.1 - 1.8e-10 40.9 0.6 5.2e-10 39.5 0.4 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 KEY69878.1 - 9.1e-08 31.4 0.3 2e-07 30.3 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KEY69878.1 - 6.8e-05 22.3 0.2 0.00017 21.0 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KEY69878.1 - 0.00016 20.9 0.1 0.00016 20.9 0.0 2.4 2 0 0 2 2 2 1 SH3 domain Pkinase PF00069.20 KEY69879.1 - 5.8e-70 235.4 0.0 8.5e-70 234.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY69879.1 - 9.9e-50 169.0 0.0 1.5e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY69879.1 - 1.8e-06 27.1 0.0 4.3e-06 25.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.6 KEY69879.1 - 0.061 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) TBPIP PF07106.8 KEY69880.1 - 0.0051 16.3 10.5 0.0051 16.3 7.3 2.5 1 1 1 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc42p PF11544.3 KEY69880.1 - 0.015 15.2 1.9 0.097 12.6 1.3 2.5 1 0 0 1 1 1 0 Spindle pole body component Spc42p CENP-F_leu_zip PF10473.4 KEY69880.1 - 0.22 11.3 21.6 2.9 7.7 10.6 3.1 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prominin PF05478.6 KEY69880.1 - 1.1 6.7 2.6 1.8 5.9 1.8 1.3 1 0 0 1 1 1 0 Prominin Pox_A_type_inc PF04508.7 KEY69880.1 - 2.6 8.0 16.4 1.5 8.8 0.1 4.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Nup54 PF13874.1 KEY69880.1 - 5.5 6.6 17.8 7.8 6.1 0.1 2.7 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 RAI1 PF08652.6 KEY69881.1 - 3.2e-28 97.3 0.0 6.3e-28 96.3 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease COX5A PF02284.11 KEY69882.1 - 2.9e-40 136.5 0.3 3.6e-40 136.2 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va ELO PF01151.13 KEY69883.1 - 3.2e-63 213.3 21.0 3.9e-63 213.0 14.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family F-box-like PF12937.2 KEY69884.1 - 2.2e-06 27.2 0.5 4.7e-06 26.2 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEY69884.1 - 0.0052 16.4 0.4 0.04 13.5 0.3 2.3 1 1 0 1 1 1 1 F-box domain Glycogen_syn PF05693.8 KEY69887.1 - 0 1139.6 0.0 0 1139.4 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 KEY69887.1 - 1.7e-06 27.5 0.0 0.0032 16.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 KEY69887.1 - 4.5e-06 26.3 0.1 9.5e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 KEY69887.1 - 1.2e-05 25.5 0.0 3e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain WD40 PF00400.27 KEY69888.1 - 3.5e-29 99.5 12.4 1.1e-06 28.2 0.0 7.4 7 1 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.7 KEY69888.1 - 4.5e-19 68.2 0.2 7.1e-19 67.5 0.1 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain DNA_pol_A_exo1 PF01612.15 KEY69889.1 - 2.8e-14 52.9 0.0 4.5e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease LSM PF01423.17 KEY69890.1 - 3.8e-21 74.4 0.0 4.2e-21 74.2 0.0 1.0 1 0 0 1 1 1 1 LSM domain RNA_pol_L_2 PF13656.1 KEY69891.1 - 8.9e-23 79.5 0.1 1.2e-22 79.1 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KEY69891.1 - 4.3e-09 35.3 0.0 7.1e-09 34.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SIR2_2 PF13289.1 KEY69891.1 - 0.12 12.2 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 SIR2-like domain Methyltransf_26 PF13659.1 KEY69892.1 - 2.2e-13 50.2 0.1 7.5e-13 48.5 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY69892.1 - 9.6e-06 26.1 0.0 1.8e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY69892.1 - 5.2e-05 22.8 0.0 9.3e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY69892.1 - 0.0001 21.7 0.0 0.0035 16.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase small domain N6_Mtase PF02384.11 KEY69892.1 - 0.00096 18.3 0.0 0.0014 17.7 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase PrmA PF06325.8 KEY69892.1 - 0.081 12.0 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 KEY69892.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_M41 PF01434.13 KEY69893.1 - 9.8e-76 253.9 0.1 1.5e-75 253.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KEY69893.1 - 1.1e-41 142.1 0.0 6.6e-41 139.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 KEY69893.1 - 7.5e-08 32.5 0.7 1.7e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.9 KEY69893.1 - 0.0012 18.5 0.0 0.0048 16.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEY69893.1 - 0.0026 17.8 0.2 0.69 10.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.8 KEY69893.1 - 0.0031 16.3 0.1 0.0055 15.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 KEY69893.1 - 0.0039 17.9 0.0 0.024 15.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KEY69893.1 - 0.0064 16.4 0.0 0.05 13.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 KEY69893.1 - 0.0066 16.1 1.6 0.051 13.3 0.8 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 KEY69893.1 - 0.0083 15.5 0.6 0.031 13.6 0.2 2.1 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 KEY69893.1 - 0.02 13.9 0.0 0.058 12.4 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 KEY69893.1 - 0.021 13.9 0.2 0.054 12.5 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.12 KEY69893.1 - 0.028 13.8 0.0 0.081 12.3 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 KEY69893.1 - 0.029 14.3 0.2 0.5 10.3 0.1 2.5 1 1 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 KEY69893.1 - 0.036 13.9 0.0 0.43 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KEY69893.1 - 0.049 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain HCO3_cotransp PF00955.16 KEY69894.1 - 6.3e-66 223.0 13.0 2.1e-40 138.8 1.5 2.0 1 1 1 2 2 2 2 HCO3- transporter family TIMELESS PF04821.9 KEY69895.1 - 8.1e-92 307.2 2.1 3.8e-91 305.0 0.0 2.4 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.8 KEY69895.1 - 1.9e-29 103.0 1.8 1.9e-29 103.0 1.2 4.2 2 1 2 4 4 4 2 Timeless protein C terminal region 3HCDH_N PF02737.13 KEY69896.1 - 1.3e-52 178.1 0.8 1.7e-52 177.7 0.5 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KEY69896.1 - 2.2e-33 114.5 0.0 1.1e-32 112.2 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Saccharop_dh PF03435.13 KEY69896.1 - 0.00082 18.4 0.0 0.0014 17.6 0.0 1.5 1 1 1 2 2 2 1 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 KEY69896.1 - 0.0013 18.5 0.1 0.0031 17.3 0.0 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 KEY69896.1 - 0.01 15.5 0.3 0.022 14.5 0.2 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 KEY69896.1 - 0.015 15.2 0.0 0.09 12.7 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.1 KEY69896.1 - 0.017 15.2 0.4 0.31 11.0 0.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 KEY69896.1 - 0.023 15.1 0.9 0.091 13.1 0.6 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.19 KEY69896.1 - 0.023 13.6 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEY69896.1 - 0.026 14.9 0.1 0.075 13.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KEY69896.1 - 0.029 13.7 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 KEY69896.1 - 0.081 12.0 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 KEY69896.1 - 0.092 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Homeobox PF00046.24 KEY69897.1 - 1.1e-17 63.3 2.8 2.1e-17 62.4 2.0 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KEY69897.1 - 0.0033 17.0 0.1 0.0082 15.8 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Fox-1_C PF12414.3 KEY69897.1 - 0.0083 16.5 0.1 0.027 14.8 0.1 1.9 1 0 0 1 1 1 1 Calcitonin gene-related peptide regulator C terminal Rox3 PF08633.5 KEY69898.1 - 2.4e-48 165.0 0.3 2.4e-48 165.0 0.2 1.9 2 0 0 2 2 2 1 Rox3 mediator complex subunit Fungal_trans PF04082.13 KEY69899.1 - 7e-29 100.4 0.0 1.3e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY69899.1 - 1.5e-09 37.5 12.5 2.6e-09 36.8 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain efThoc1 PF11957.3 KEY69899.1 - 0.068 11.6 0.0 0.068 11.6 0.0 1.6 2 0 0 2 2 2 0 THO complex subunit 1 transcription elongation factor FAD_binding_3 PF01494.14 KEY69901.1 - 5.2e-17 61.9 0.0 1.6e-05 24.1 0.0 3.0 3 0 0 3 3 3 3 FAD binding domain Pyr_redox PF00070.22 KEY69901.1 - 2.4e-07 31.0 0.1 0.00022 21.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY69901.1 - 4.4e-07 29.8 0.1 1.5e-06 28.1 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEY69901.1 - 1e-06 27.9 0.0 0.00025 20.0 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEY69901.1 - 0.0019 17.1 0.0 0.0035 16.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KEY69901.1 - 0.0058 15.7 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KEY69901.1 - 0.012 14.0 0.0 0.029 12.8 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 KEY69901.1 - 0.016 14.1 0.0 0.046 12.6 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEY69901.1 - 0.017 14.9 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KEY69901.1 - 0.027 14.1 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 KEY69901.1 - 0.066 11.8 0.0 2.4 6.6 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KEY69901.1 - 0.074 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 KEY69901.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 KEY69901.1 - 0.21 11.3 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TPP_enzyme_N PF02776.13 KEY69903.1 - 1.4e-56 190.6 0.0 9.7e-56 187.9 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KEY69903.1 - 1.5e-49 167.5 0.3 6.4e-48 162.2 0.1 2.8 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KEY69903.1 - 9.3e-36 122.6 0.8 2.4e-35 121.2 0.4 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Ycf1 PF05758.7 KEY69904.1 - 0.058 11.1 5.7 0.077 10.7 4.0 1.1 1 0 0 1 1 1 0 Ycf1 Macoilin PF09726.4 KEY69904.1 - 0.14 10.3 14.5 0.22 9.7 10.0 1.2 1 0 0 1 1 1 0 Transmembrane protein Neur_chan_memb PF02932.11 KEY69904.1 - 0.2 11.4 6.5 0.079 12.8 2.5 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.9 KEY69904.1 - 2.1 6.2 13.7 3.1 5.6 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 KEY69904.1 - 3.3 5.2 13.8 4.8 4.7 9.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Med15 PF09606.5 KEY69904.1 - 3.3 5.7 54.6 4.8 5.2 37.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal zf-C2H2_4 PF13894.1 KEY69906.1 - 0.011 16.0 10.7 0.15 12.4 0.4 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY69906.1 - 0.12 12.8 12.9 0.4 11.1 0.9 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type KAR9 PF08580.5 KEY69906.1 - 0.68 8.1 8.6 1 7.5 6.0 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 GalKase_gal_bdg PF10509.4 KEY69907.1 - 1e-20 72.7 0.1 2e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 KEY69907.1 - 5.7e-14 51.9 2.0 1.7e-13 50.3 1.4 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KEY69907.1 - 1.3e-11 44.5 0.1 4.5e-11 42.7 0.1 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal Sigma70_r4_2 PF08281.7 KEY69907.1 - 0.0087 15.4 0.1 0.019 14.4 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Zn_clus PF00172.13 KEY69908.1 - 6.2e-07 29.2 18.5 1e-06 28.5 12.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RINGv PF12906.2 KEY69911.1 - 0.00051 20.0 8.8 0.0008 19.4 6.1 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KEY69911.1 - 0.0015 18.2 10.3 0.0026 17.5 7.2 1.4 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 KEY69911.1 - 0.15 12.0 7.2 0.26 11.2 5.0 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain DUF2360 PF10152.4 KEY69911.1 - 0.25 11.6 3.2 0.54 10.5 2.2 1.6 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) zf-rbx1 PF12678.2 KEY69911.1 - 0.25 11.4 5.4 0.49 10.5 3.8 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 KEY69911.1 - 1.9 8.1 9.3 3 7.5 6.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.1 KEY69912.1 - 1.4e-18 66.2 7.7 3.5e-15 55.3 2.8 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KEY69912.1 - 6.8e-16 57.1 4.3 1.5e-07 30.7 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEY69912.1 - 2.2e-15 55.2 5.0 5.1e-06 26.0 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEY69912.1 - 9.3e-08 31.6 2.4 0.023 14.8 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEY69912.1 - 5.4e-07 30.1 9.4 1.6e-06 28.6 1.9 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEY69912.1 - 5.6e-07 29.6 6.8 0.00083 19.7 0.3 3.6 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEY69912.1 - 2.8e-06 26.7 0.2 0.04 13.7 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEY69912.1 - 9.3e-06 25.4 6.6 7.3e-05 22.6 2.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEY69912.1 - 0.00018 21.0 3.3 0.26 11.1 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEY69912.1 - 0.00077 19.7 5.7 0.0017 18.6 0.3 2.8 2 1 1 3 3 2 1 Tetratricopeptide repeat XPC-binding PF09280.6 KEY69912.1 - 0.0069 15.8 3.1 0.0082 15.5 0.6 2.1 2 0 0 2 2 2 1 XPC-binding domain BTAD PF03704.12 KEY69912.1 - 0.0078 16.5 2.7 0.4 10.9 0.2 2.2 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_6 PF13174.1 KEY69912.1 - 0.013 15.9 3.6 3.5 8.2 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 KEY69912.1 - 0.034 13.9 0.3 0.52 10.1 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 KEY69912.1 - 0.049 13.4 2.6 0.46 10.3 0.9 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat SR-25 PF10500.4 KEY69912.1 - 0.072 12.5 2.9 0.12 11.8 2.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MIT PF04212.13 KEY69912.1 - 0.27 11.1 2.6 1.9 8.3 0.2 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 KEY69912.1 - 0.85 9.7 4.4 18 5.5 0.4 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KEY69912.1 - 1.2 9.1 6.4 0.82 9.6 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ABC_tran PF00005.22 KEY69913.1 - 5.1e-33 114.2 0.0 9.7e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KEY69913.1 - 8.9e-05 22.0 7.1 0.00019 20.9 4.9 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 KEY69913.1 - 0.00041 20.4 0.0 0.011 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KEY69913.1 - 0.00048 19.4 0.0 0.0051 16.0 0.0 2.0 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KEY69913.1 - 0.00062 20.5 0.3 0.0022 18.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KEY69913.1 - 0.0028 16.8 0.0 0.0052 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PAM2 PF07145.10 KEY69913.1 - 0.0074 15.7 0.2 0.015 14.7 0.2 1.5 1 0 0 1 1 1 1 Ataxin-2 C-terminal region AAA_29 PF13555.1 KEY69913.1 - 0.0086 15.5 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KEY69913.1 - 0.011 14.8 0.0 0.032 13.3 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.1 KEY69913.1 - 0.027 13.8 0.0 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KEY69913.1 - 0.05 13.9 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEY69913.1 - 0.11 12.8 0.1 0.46 10.7 0.0 2.2 3 0 0 3 3 2 0 AAA domain APS_kinase PF01583.15 KEY69913.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Zn_clus PF00172.13 KEY69914.1 - 2.3e-05 24.2 4.4 0.00039 20.2 0.2 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain ScdA_N PF04405.9 KEY69914.1 - 0.061 12.7 0.2 0.15 11.4 0.2 1.6 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) bZIP_1 PF00170.16 KEY69915.1 - 3.9e-09 36.3 3.0 3.9e-09 36.3 2.1 3.0 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 KEY69915.1 - 0.002 17.9 0.8 0.002 17.9 0.6 2.8 3 0 0 3 3 3 1 Basic region leucine zipper DUF4551 PF15087.1 KEY69915.1 - 1.6 6.9 19.2 3.2 6.0 13.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) eIF-3_zeta PF05091.7 KEY69915.1 - 5.2 5.5 23.8 0.47 8.9 8.4 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Med15 PF09606.5 KEY69915.1 - 5.7 5.0 68.8 11 4.0 47.7 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MlrC_C PF07171.7 KEY69916.1 - 0.022 14.2 0.7 0.024 14.1 0.5 1.2 1 0 0 1 1 1 0 MlrC C-terminus Gly-zipper_OmpA PF13436.1 KEY69916.1 - 0.17 11.5 9.7 0.3 10.7 6.8 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain adh_short PF00106.20 KEY69917.1 - 4.4e-18 65.7 0.8 5.7e-18 65.3 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY69917.1 - 4e-10 39.6 0.2 5.7e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY69917.1 - 1.7e-06 28.0 0.0 2.2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 KEY69917.1 - 0.00017 20.5 0.0 0.0002 20.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 KEY69917.1 - 0.00038 19.5 0.5 0.00054 19.0 0.3 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 KEY69917.1 - 0.0018 18.6 0.2 0.0083 16.5 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent YjeF_N PF03853.10 KEY69917.1 - 0.0056 16.3 0.0 0.0098 15.5 0.0 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus Epimerase PF01370.16 KEY69917.1 - 0.0062 15.9 0.2 0.018 14.5 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KEY69917.1 - 0.012 15.2 0.2 0.021 14.4 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_tran_WecB PF03808.8 KEY69917.1 - 0.02 14.3 0.1 0.051 12.9 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Shikimate_DH PF01488.15 KEY69917.1 - 0.029 14.4 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 KEY69917.1 - 0.079 12.3 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 KEY69917.1 - 0.13 12.4 0.2 0.33 11.2 0.1 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding HET PF06985.6 KEY69918.1 - 3.3e-18 66.1 0.0 6.8e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PAN_4 PF14295.1 KEY69919.1 - 0.00072 19.2 0.1 0.0014 18.2 0.1 1.5 1 0 0 1 1 1 1 PAN domain adh_short PF00106.20 KEY69920.1 - 2.6e-10 40.4 0.0 1e-09 38.5 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY69920.1 - 0.00027 20.6 0.0 0.00097 18.8 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KEY69920.1 - 0.016 14.6 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KEY69920.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F-box-like PF12937.2 KEY69922.1 - 7e-06 25.6 0.1 1.7e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEY69922.1 - 0.00068 19.2 0.2 0.0021 17.6 0.1 1.9 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 KEY69925.1 - 2.4e-133 429.8 69.6 2.4e-13 49.4 0.0 13.6 13 0 0 13 13 13 13 WD domain, G-beta repeat NACHT PF05729.7 KEY69925.1 - 4.4e-23 81.7 0.1 9e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain HET PF06985.6 KEY69925.1 - 6.2e-21 75.0 5.5 2.7e-19 69.6 3.8 2.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nup160 PF11715.3 KEY69925.1 - 1.9e-11 42.8 30.7 0.00093 17.4 0.1 9.5 1 1 7 9 9 9 6 Nucleoporin Nup120/160 Nbas_N PF15492.1 KEY69925.1 - 1.7e-07 30.6 26.8 0.22 10.6 0.1 9.2 2 2 7 10 10 10 5 Neuroblastoma-amplified sequence, N terminal AAA_19 PF13245.1 KEY69925.1 - 0.0097 15.6 0.0 0.042 13.6 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain Plectin PF00681.15 KEY69925.1 - 0.016 14.7 0.0 1.3e+02 2.2 0.0 5.7 7 0 0 7 7 7 0 Plectin repeat DUF1652 PF07865.6 KEY69925.1 - 0.023 14.3 0.0 7.6 6.2 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1652) AAA_11 PF13086.1 KEY69925.1 - 0.13 11.7 0.0 0.33 10.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain Peptidase_M14 PF00246.19 KEY69926.1 - 3.3e-68 230.3 0.0 4.5e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase TRAM PF01938.15 KEY69926.1 - 0.0091 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 TRAM domain CHAT PF12770.2 KEY69928.1 - 4.3e-10 39.1 0.0 8.7e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 CHAT domain AAA_22 PF13401.1 KEY69928.1 - 1.8e-06 28.0 0.0 6.1e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEY69928.1 - 0.003 17.5 0.0 0.0074 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 KEY69928.1 - 0.0037 16.9 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 KEY69928.1 - 0.032 13.8 0.0 0.075 12.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 KEY69928.1 - 0.17 10.6 0.0 2.2 7.0 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 KEY69928.1 - 0.33 10.5 0.0 0.71 9.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2867 PF11066.3 KEY69930.1 - 1.2e-38 132.1 0.1 8.2e-38 129.4 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2867) tRNA-synt_His PF13393.1 KEY69931.1 - 1.8e-43 148.7 0.0 2.3e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KEY69931.1 - 2.3e-17 63.0 0.0 4.1e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KEY69931.1 - 7.5e-09 35.4 0.0 1.5e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 KEY69931.1 - 4e-05 22.5 0.0 0.0021 16.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) RHD3 PF05879.7 KEY69931.1 - 0.046 11.6 0.0 0.065 11.1 0.0 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) PAD PF03068.10 KEY69932.1 - 7e-52 176.1 0.0 7.3e-51 172.7 0.0 2.2 1 1 0 1 1 1 1 Protein-arginine deiminase (PAD) Acyl-CoA_dh_1 PF00441.19 KEY69935.1 - 4.2e-24 85.3 0.6 7.5e-24 84.5 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KEY69935.1 - 1e-11 44.1 0.2 2.7e-11 42.7 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KEY69935.1 - 2.3e-06 28.1 0.2 5.2e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KEY69935.1 - 5.2e-06 26.7 1.6 5.2e-06 26.7 1.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain IDO PF01231.13 KEY69936.1 - 2e-07 29.8 1.3 5.7e-06 25.0 0.9 2.1 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase Peptidase_C12 PF01088.16 KEY69937.1 - 1.7e-64 216.9 0.0 2.1e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 MAD PF05557.8 KEY69939.1 - 6e-60 203.1 52.8 7.5e-60 202.8 36.6 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein HALZ PF02183.13 KEY69939.1 - 0.019 14.6 27.0 0.68 9.6 0.2 7.9 7 0 0 7 7 7 0 Homeobox associated leucine zipper LPP PF04728.8 KEY69939.1 - 0.034 13.9 18.2 1.2 8.9 0.4 5.6 5 0 0 5 5 5 0 Lipoprotein leucine-zipper GAS PF13851.1 KEY69939.1 - 0.23 10.6 80.1 0.11 11.6 4.3 6.0 5 1 1 6 6 6 0 Growth-arrest specific micro-tubule binding DUF4618 PF15397.1 KEY69939.1 - 1.2 8.4 56.4 0.14 11.5 17.4 5.8 3 3 1 5 5 5 0 Domain of unknown function (DUF4618) Mmp37 PF09139.6 KEY69940.1 - 4.9e-127 423.5 0.0 6e-127 423.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 muHD PF10291.4 KEY69941.1 - 1.6e-62 210.9 0.0 3.3e-62 209.9 0.0 1.5 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 KEY69941.1 - 1.5e-10 41.1 0.5 1.5e-09 37.8 0.0 2.6 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Vps5 PF09325.5 KEY69941.1 - 0.15 11.2 11.4 0.014 14.6 4.1 1.8 2 0 0 2 2 2 0 Vps5 C terminal like LUC7 PF03194.10 KEY69941.1 - 0.83 9.1 4.9 1.7 8.0 3.4 1.5 1 0 0 1 1 1 0 LUC7 N_terminus DDRGK PF09756.4 KEY69941.1 - 1.7 7.9 6.7 3.3 7.0 4.7 1.4 1 0 0 1 1 1 0 DDRGK domain V_ATPase_I PF01496.14 KEY69941.1 - 7.3 4.3 5.0 13 3.5 3.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pkinase PF00069.20 KEY69942.1 - 4.6e-39 134.1 0.0 6.2e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY69942.1 - 2.1e-18 66.3 0.0 3e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEY69942.1 - 0.032 13.9 0.2 0.94 9.1 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KEY69942.1 - 0.16 10.9 0.0 0.28 10.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like zf-RING_2 PF13639.1 KEY69943.1 - 2.6e-09 36.7 7.8 4.9e-09 35.8 5.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEY69943.1 - 9.6e-08 32.0 2.2 2.2e-07 30.8 1.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 KEY69943.1 - 3.9e-06 26.7 8.3 1.1e-05 25.2 5.8 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 KEY69943.1 - 0.00026 20.9 7.7 0.00055 19.9 5.3 1.6 1 0 0 1 1 1 1 RING-variant domain zf-Apc11 PF12861.2 KEY69943.1 - 0.00026 20.7 2.6 0.00065 19.4 1.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger C1_1 PF00130.17 KEY69943.1 - 0.002 17.8 2.1 0.002 17.8 1.5 1.7 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.20 KEY69943.1 - 0.004 16.7 9.5 0.0076 15.8 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEY69943.1 - 0.0044 16.6 5.2 0.0076 15.8 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEY69943.1 - 0.0092 15.9 8.7 0.018 15.0 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_RING PF05883.6 KEY69943.1 - 0.043 13.6 1.5 0.28 10.9 1.1 2.2 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-RING-like PF08746.6 KEY69943.1 - 0.073 13.0 7.7 0.14 12.1 5.3 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_5 PF14634.1 KEY69943.1 - 0.98 9.1 8.6 1.8 8.3 5.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.24 KEY69943.1 - 4.9 6.9 6.7 9.4 6.0 4.6 1.5 1 0 0 1 1 1 0 PHD-finger Herpes_capsid PF06112.6 KEY69945.1 - 7.2 6.6 12.8 9.7 6.2 8.9 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Ribosomal_L1 PF00687.16 KEY69947.1 - 1.9e-57 194.1 0.8 1.9e-57 194.1 0.6 1.5 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Palm_thioest PF02089.10 KEY69948.1 - 6.9e-57 192.5 0.0 8.4e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.6 KEY69948.1 - 0.049 12.7 0.0 0.087 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Cyclin_N PF00134.18 KEY69949.1 - 3.6e-10 39.4 0.0 7e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pmp3 PF01679.12 KEY69951.1 - 3.2e-18 65.1 6.7 4.2e-18 64.7 4.7 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Arb1 PF09692.5 KEY69952.1 - 4.8e-91 305.5 0.0 5.7e-91 305.2 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 IPK PF03770.11 KEY69953.1 - 3e-50 170.6 0.0 4.4e-50 170.0 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Clp1 PF06807.9 KEY69953.1 - 1.6e-20 73.7 0.0 3e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KEY69953.1 - 4.6e-06 26.4 0.0 2.2e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 KEY69953.1 - 9.5e-05 22.0 0.3 0.00046 19.8 0.3 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 KEY69953.1 - 0.00076 19.5 0.1 0.002 18.1 0.0 1.9 2 1 0 2 2 1 1 AAA ATPase domain ATP_bind_1 PF03029.12 KEY69953.1 - 0.00099 18.7 0.2 0.0028 17.2 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein KTI12 PF08433.5 KEY69953.1 - 0.0038 16.4 0.1 0.017 14.3 0.0 1.9 2 0 0 2 2 2 1 Chromatin associated protein KTI12 IstB_IS21 PF01695.12 KEY69953.1 - 0.011 15.1 0.0 0.057 12.8 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.24 KEY69953.1 - 0.014 15.6 0.8 0.082 13.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 KEY69953.1 - 0.03 14.2 0.0 0.12 12.3 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_10 PF12846.2 KEY69953.1 - 0.031 13.7 0.0 0.06 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 KEY69953.1 - 0.043 14.6 2.1 0.13 13.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain ArgK PF03308.11 KEY69953.1 - 0.068 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 ArgK protein T2SE PF00437.15 KEY69953.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.17 KEY69953.1 - 0.14 11.5 0.0 0.86 9.0 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain E1-E2_ATPase PF00122.15 KEY69954.1 - 1.1e-59 201.3 7.0 1.1e-59 201.3 4.8 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEY69954.1 - 1.3e-31 109.5 4.9 1.3e-31 109.5 3.4 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEY69954.1 - 4.4e-29 102.4 0.5 1.2e-24 87.8 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEY69954.1 - 8e-18 63.6 0.0 2.3e-17 62.1 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KEY69954.1 - 8.3e-15 54.5 0.0 2e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEY69954.1 - 1.4e-10 41.6 3.8 4.4e-10 40.0 2.6 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEY69954.1 - 6.1e-07 29.2 0.8 3.7e-05 23.4 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.5 KEY69954.1 - 0.011 15.3 1.7 0.026 14.0 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) HET PF06985.6 KEY69955.1 - 1.7e-23 83.3 0.0 3.1e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CRAL_TRIO PF00650.15 KEY69956.1 - 5e-27 94.3 0.0 7.4e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KEY69956.1 - 3.5e-08 33.4 0.1 7.6e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Abhydrolase_5 PF12695.2 KEY69958.1 - 0.00018 21.3 0.1 0.00025 20.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 KEY69958.1 - 0.023 13.4 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.2 KEY69958.1 - 0.04 12.7 0.0 0.052 12.4 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 KEY69958.1 - 0.051 13.1 0.2 0.065 12.8 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold VWA_2 PF13519.1 KEY69959.1 - 2.1e-22 80.0 3.6 3.2e-22 79.4 1.3 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 KEY69959.1 - 9.1e-17 61.3 0.1 1.4e-16 60.7 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KEY69959.1 - 7.4e-05 22.4 0.6 0.00016 21.3 0.1 1.9 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 KEY69959.1 - 0.029 13.5 0.7 0.15 11.1 0.5 2.0 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein Tyrosinase PF00264.15 KEY69959.1 - 0.032 14.3 0.7 0.056 13.5 0.5 1.4 1 0 0 1 1 1 0 Common central domain of tyrosinase vWA-TerF-like PF10138.4 KEY69959.1 - 0.1 12.4 0.0 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 vWA found in TerF C terminus Hemocyanin_M PF00372.14 KEY69959.1 - 0.33 10.1 0.0 0.64 9.2 0.0 1.4 1 0 0 1 1 1 0 Hemocyanin, copper containing domain DUF3669 PF12417.3 KEY69960.1 - 1.6e-16 59.7 0.0 3.5e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Zinc finger protein Zn_clus PF00172.13 KEY69961.1 - 0.11 12.4 15.1 0.068 13.0 1.5 2.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain p47_phox_C PF08944.6 KEY69961.1 - 0.14 12.3 1.3 0.31 11.2 0.9 1.5 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain CAP59_mtransfer PF11735.3 KEY69963.1 - 1.1e-59 201.6 0.0 1.5e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Mito_fiss_reg PF05308.6 KEY69966.1 - 0.037 13.4 1.2 0.041 13.2 0.8 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3405 PF11885.3 KEY69968.1 - 1.4e-183 610.7 0.1 2.6e-183 609.8 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) Rho_N PF07498.7 KEY69969.1 - 0.0053 16.4 0.2 0.01 15.5 0.2 1.5 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain DUF3338 PF11819.3 KEY69969.1 - 0.046 13.1 0.2 2.8 7.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3338) HTH_AsnC-type PF13404.1 KEY69969.1 - 0.36 10.4 1.9 8.5 6.0 0.9 3.1 2 1 0 2 2 2 0 AsnC-type helix-turn-helix domain p450 PF00067.17 KEY69970.1 - 9.5e-52 176.0 0.0 3.6e-51 174.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 DUF1206 PF06724.6 KEY69970.1 - 0.079 12.7 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) HAD_2 PF13419.1 KEY69973.1 - 2.3e-17 63.7 0.0 2.1e-16 60.6 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEY69973.1 - 0.00084 19.0 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Ribosomal_L18p PF00861.17 KEY69974.1 - 2e-42 144.1 0.2 2e-42 144.1 0.1 1.7 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KEY69974.1 - 1.2e-32 112.3 10.0 1.2e-32 112.3 7.0 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L6e PF01159.14 KEY69974.1 - 2.5 8.3 11.1 0.81 9.9 4.1 2.2 2 0 0 2 2 2 0 Ribosomal protein L6e LRR_6 PF13516.1 KEY69975.1 - 0.036 14.1 4.9 59 4.1 0.0 6.2 8 0 0 8 8 8 0 Leucine Rich repeat LRR_4 PF12799.2 KEY69975.1 - 2.2 7.9 13.0 2.3 7.9 0.1 5.3 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KEY69975.1 - 2.7 8.5 7.2 65 4.4 0.1 5.9 7 0 0 7 7 7 0 Leucine rich repeat PS_Dcarbxylase PF02666.10 KEY69977.1 - 6.7e-52 175.7 0.0 1.9e-51 174.2 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase C2 PF00168.25 KEY69977.1 - 6.2e-35 118.9 0.1 1.2e-17 63.4 0.0 2.6 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 KEY69977.1 - 0.0031 17.6 0.2 0.014 15.5 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KEY69977.1 - 0.013 15.3 0.0 0.041 13.7 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.1 KEY69977.1 - 0.027 13.8 0.0 0.085 12.2 0.0 1.9 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.27 KEY69977.1 - 0.032 13.5 0.0 0.098 12.0 0.0 1.9 1 0 0 1 1 1 0 EF hand Fungal_trans PF04082.13 KEY69978.1 - 2.5e-12 46.2 0.5 4.4e-12 45.4 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KEY69978.1 - 6.1e-07 29.4 12.0 0.0031 17.7 1.3 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY69978.1 - 6.7e-07 29.2 10.9 0.00067 19.8 2.2 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger CTP_transf_2 PF01467.21 KEY69979.1 - 1e-21 77.5 0.0 2e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase RRM_1 PF00076.17 KEY69980.1 - 7.6e-38 127.9 0.3 9.7e-18 63.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY69980.1 - 5e-28 96.8 2.5 4.3e-14 52.2 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY69980.1 - 2.7e-12 46.3 2.2 1.4e-05 24.7 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEY69980.1 - 0.011 15.4 0.0 6.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KEY69980.1 - 0.33 10.8 3.7 12 5.7 0.0 2.9 3 0 0 3 3 3 0 RNA binding motif TFIIA PF03153.8 KEY69980.1 - 0.67 9.7 18.5 0.86 9.4 12.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ANTH PF07651.11 KEY69980.1 - 1.2 7.8 5.9 1.6 7.3 4.1 1.2 1 0 0 1 1 1 0 ANTH domain DUF4618 PF15397.1 KEY69980.1 - 3.4 6.9 16.9 4.8 6.4 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF4620 PF15399.1 KEY69981.1 - 0.29 11.2 3.3 0.46 10.6 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) RabGAP-TBC PF00566.13 KEY69982.1 - 3.4e-46 157.4 0.1 8.6e-46 156.1 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Glyco_transf_90 PF05686.7 KEY69983.1 - 5.9e-14 51.5 0.6 7.5e-11 41.3 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 90 Oxidored_q6 PF01058.17 KEY69984.1 - 2.9e-22 78.6 0.0 4.1e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit HECT PF00632.20 KEY69985.1 - 6.8e-93 311.2 0.0 9.6e-93 310.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KEY69985.1 - 2.1e-33 113.7 21.9 1.8e-11 43.6 4.6 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.25 KEY69985.1 - 2e-17 62.8 0.1 5.3e-17 61.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain RRM_1 PF00076.17 KEY69986.1 - 9.3e-17 60.4 0.0 1.5e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY69986.1 - 4.6e-15 55.3 0.0 8e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY69986.1 - 3.5e-06 26.7 0.0 5.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IncA PF04156.9 KEY69986.1 - 0.0053 16.3 1.1 0.0066 16.0 0.7 1.1 1 0 0 1 1 1 1 IncA protein V_ATPase_I PF01496.14 KEY69986.1 - 0.033 12.0 0.2 0.039 11.8 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CASP_C PF08172.7 KEY69986.1 - 0.055 12.4 0.1 0.077 12.0 0.1 1.1 1 0 0 1 1 1 0 CASP C terminal NPV_P10 PF05531.7 KEY69986.1 - 0.068 13.4 0.3 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Nup35_RRM_2 PF14605.1 KEY69986.1 - 0.081 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF904 PF06005.7 KEY69986.1 - 0.21 11.8 4.0 0.34 11.2 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Packaging_FI PF14000.1 KEY69986.1 - 0.64 10.2 5.4 0.91 9.7 3.6 1.5 1 1 0 1 1 1 0 DNA packaging protein FI DivIC PF04977.10 KEY69986.1 - 0.71 9.3 4.6 1.1 8.7 3.2 1.3 1 0 0 1 1 1 0 Septum formation initiator GRP PF07172.6 KEY69986.1 - 1 9.9 16.0 0.04 14.4 7.0 1.7 2 0 0 2 2 2 0 Glycine rich protein family Ion_trans PF00520.26 KEY69987.1 - 3.2e-08 33.0 2.4 5e-08 32.4 1.6 1.3 1 0 0 1 1 1 1 Ion transport protein Mto2_bdg PF12808.2 KEY69987.1 - 0.011 15.8 0.3 0.02 14.9 0.2 1.3 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_1 PF00170.16 KEY69987.1 - 0.013 15.4 0.3 0.021 14.7 0.2 1.2 1 0 0 1 1 1 0 bZIP transcription factor HALZ PF02183.13 KEY69987.1 - 0.027 14.1 1.0 0.048 13.3 0.7 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper UPF0233 PF06781.7 KEY69987.1 - 0.087 12.4 0.2 0.15 11.6 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) Shugoshin_N PF07558.6 KEY69987.1 - 0.088 12.5 1.2 0.15 11.7 0.8 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.10 KEY69987.1 - 0.65 9.8 5.2 0.16 11.8 1.4 1.5 2 0 0 2 2 2 0 Basic region leucine zipper DUF4588 PF15251.1 KEY69988.1 - 0.0012 18.8 6.5 0.0041 17.1 4.5 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Hairy_orange PF07527.8 KEY69988.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Hairy Orange SNF2_N PF00176.18 KEY69989.1 - 1.6e-83 279.9 0.1 2.7e-83 279.1 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 KEY69989.1 - 2.2e-43 146.7 2.9 6.6e-43 145.2 2.0 1.9 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 KEY69989.1 - 1.3e-32 112.4 4.1 1.3e-32 112.4 2.8 4.2 6 0 0 6 6 6 1 HAND Helicase_C PF00271.26 KEY69989.1 - 5.2e-15 55.0 0.0 1.5e-14 53.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEY69989.1 - 1.3e-08 34.9 0.0 1.7e-07 31.2 0.0 3.1 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KEY69989.1 - 2.1e-05 24.1 0.0 4.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 KEY69989.1 - 0.016 14.5 0.2 0.034 13.5 0.2 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.1 KEY69989.1 - 0.041 13.7 0.1 0.16 11.8 0.1 2.0 1 0 0 1 1 1 0 AAA domain Mem_trans PF03547.13 KEY69989.1 - 1.6 6.9 2.7 3.1 5.9 1.8 1.4 1 0 0 1 1 1 0 Membrane transport protein WD40 PF00400.27 KEY69990.1 - 1.1e-30 104.3 2.7 1.4e-10 40.5 0.1 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 KEY69990.1 - 0.0036 17.0 0.1 0.77 9.4 0.0 3.1 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KEY69990.1 - 0.014 14.1 0.0 0.29 9.8 0.0 2.4 1 1 2 3 3 3 0 Nup133 N terminal like Nup160 PF11715.3 KEY69990.1 - 0.02 13.0 0.0 0.026 12.6 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 SdiA-regulated PF06977.6 KEY69990.1 - 0.046 12.6 0.0 4.1 6.2 0.0 2.5 3 0 0 3 3 3 0 SdiA-regulated Coatomer_WDAD PF04053.9 KEY69990.1 - 0.056 12.2 0.1 0.37 9.5 0.0 1.9 1 1 1 2 2 2 0 Coatomer WD associated region zf-MIZ PF02891.15 KEY69991.1 - 3.2e-06 26.5 8.8 1.5e-05 24.3 6.1 2.1 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger SH3_9 PF14604.1 KEY69992.1 - 1.7e-13 49.9 0.0 3.3e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 KEY69992.1 - 5e-13 48.6 0.0 9.7e-13 47.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 KEY69992.1 - 1.7e-11 43.3 0.0 3.3e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 KEY69992.1 - 1.2e-09 38.2 0.0 3.5e-09 36.7 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KEY69992.1 - 1.9e-06 28.0 0.2 5.4e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.12 KEY69992.1 - 5.1e-05 22.6 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.1 KEY69992.1 - 0.0016 18.4 0.0 0.0092 16.0 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain SAM_1 PF00536.25 KEY69992.1 - 0.11 12.7 0.1 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Fork_head PF00250.13 KEY69993.1 - 2.9e-10 40.0 0.0 5.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KEY69993.1 - 4.6e-06 26.6 0.0 1.3e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 FHA domain MAPEG PF01124.13 KEY69994.1 - 0.0062 16.1 0.1 2 8.0 0.1 2.5 2 1 0 2 2 2 2 MAPEG family NfeD PF01957.13 KEY69994.1 - 1.5 8.9 4.4 0.56 10.3 0.1 2.2 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding Sulfate_transp PF00916.15 KEY69995.1 - 0.00097 18.2 3.0 0.00097 18.2 2.1 2.9 3 1 0 3 3 3 2 Sulfate transporter family PGAP1 PF07819.8 KEY69997.1 - 7.1e-08 32.3 0.1 1.8e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KEY69997.1 - 2.7e-06 27.4 2.6 1.2e-05 25.3 1.6 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KEY69997.1 - 4.3e-06 26.1 0.0 9.4e-06 25.0 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 KEY69997.1 - 0.00035 20.3 0.2 0.00058 19.6 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KEY69997.1 - 0.00065 19.9 0.0 0.00097 19.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 KEY69997.1 - 0.001 18.6 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 KEY69997.1 - 0.0053 15.7 0.0 0.0079 15.2 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Ser_hydrolase PF06821.8 KEY69997.1 - 0.0073 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase DUF915 PF06028.6 KEY69997.1 - 0.063 12.3 0.0 0.15 11.1 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) RTA1 PF04479.8 KEY69998.1 - 1.3e-14 54.2 7.8 2e-14 53.6 5.4 1.2 1 0 0 1 1 1 1 RTA1 like protein NAD_binding_6 PF08030.7 KEY70000.1 - 4.3e-20 72.2 0.0 6.4e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KEY70000.1 - 5.9e-13 49.0 8.3 5.9e-13 49.0 5.8 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KEY70000.1 - 1.1e-10 41.2 0.0 3.4e-10 39.7 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 KEY70000.1 - 0.086 13.4 0.0 13 6.4 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF3733 PF12534.3 KEY70000.1 - 0.79 9.0 6.9 0.97 8.7 2.1 2.6 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 DPPIV_N PF00930.16 KEY70001.1 - 4.9e-108 360.8 0.3 6.5e-108 360.4 0.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KEY70001.1 - 4.2e-53 179.7 2.0 4.2e-53 179.7 1.4 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEY70001.1 - 4.5e-09 36.2 0.3 1e-08 35.0 0.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY70001.1 - 1.6e-06 28.2 2.9 3.2e-05 23.9 2.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KEY70001.1 - 0.015 14.7 0.6 0.052 12.9 0.3 1.9 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) PD40 PF07676.7 KEY70001.1 - 0.1 12.3 1.3 0.65 9.7 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Arrestin_N PF00339.24 KEY70002.1 - 3.7e-11 43.0 0.0 4.6e-06 26.5 0.0 3.3 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KEY70002.1 - 0.014 15.5 0.0 0.22 11.6 0.0 2.4 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Bul1_C PF04426.7 KEY70002.1 - 0.095 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Bul1 C terminus Clathrin PF00637.15 KEY70003.1 - 5.6e-208 680.9 37.3 1.1e-33 115.8 0.6 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 KEY70003.1 - 1.1e-31 108.4 0.8 4.4e-31 106.5 0.6 2.2 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 KEY70003.1 - 5.2e-30 101.6 4.0 3.5e-06 26.9 0.1 7.6 7 0 0 7 7 7 6 Clathrin propeller repeat TPR_12 PF13424.1 KEY70003.1 - 6.2e-05 22.8 2.2 11 6.0 0.0 6.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEY70003.1 - 0.00049 19.7 12.1 0.63 9.9 0.2 6.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEY70003.1 - 0.0023 18.2 8.8 3.1 8.1 0.0 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEY70003.1 - 2.3 8.3 12.7 24 5.1 0.1 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Peptidase_M43 PF05572.8 KEY70005.1 - 1e-18 67.3 0.0 1.5e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 KEY70005.1 - 6.2e-05 23.0 0.2 8.8e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KEY70005.1 - 0.00049 20.6 0.0 0.0011 19.4 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KEY70005.1 - 0.0089 15.5 0.2 0.015 14.8 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KEY70005.1 - 0.0091 16.0 1.8 0.018 15.1 1.3 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KEY70005.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Matrixin DUF2196 PF09962.4 KEY70006.1 - 6.6e-22 77.0 3.2 9.8e-22 76.5 2.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) zf-Di19 PF05605.7 KEY70006.1 - 0.0038 17.3 0.4 0.0053 16.8 0.2 1.2 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 KEY70006.1 - 0.0074 16.4 0.2 0.012 15.7 0.1 1.4 1 0 0 1 1 1 1 C2H2-type zinc-finger domain Zn_Tnp_IS1 PF03811.8 KEY70006.1 - 0.13 11.7 2.0 0.14 11.6 0.0 2.1 2 0 0 2 2 2 0 InsA N-terminal domain Zn_clus PF00172.13 KEY70007.1 - 0.041 13.7 14.7 0.063 13.1 10.2 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1640 PF07798.6 KEY70008.1 - 9.1e-65 217.9 5.3 1.1e-64 217.7 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) cwf21 PF08312.7 KEY70008.1 - 0.0045 16.8 0.9 0.018 14.8 0.3 2.2 2 1 0 2 2 2 1 cwf21 domain HrpB7 PF09486.5 KEY70008.1 - 0.033 14.1 4.0 0.055 13.3 2.8 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Lzipper-MIP1 PF14389.1 KEY70008.1 - 0.091 12.8 4.8 6 7.0 0.9 2.7 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 CLAMP PF14769.1 KEY70008.1 - 0.13 12.3 0.1 0.37 10.9 0.1 1.8 1 1 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 Syntaxin PF00804.20 KEY70008.1 - 0.32 11.1 6.0 2.3 8.4 3.5 2.4 1 1 0 1 1 1 0 Syntaxin FTA4 PF13093.1 KEY70008.1 - 0.46 9.8 7.3 1.2 8.5 5.0 1.6 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 2-Hacid_dh_C PF02826.14 KEY70009.1 - 3.3e-56 189.2 0.0 4.7e-56 188.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KEY70009.1 - 4.2e-20 71.5 0.0 5.2e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KEY70009.1 - 1e-05 25.4 0.1 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KEY70009.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 KEY70009.1 - 0.12 12.1 0.0 0.37 10.6 0.0 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Asp_protease_2 PF13650.1 KEY70009.1 - 0.13 12.8 0.0 2.5 8.6 0.0 2.5 2 1 0 2 2 2 0 Aspartyl protease AdoHcyase PF05221.12 KEY70010.1 - 8.6e-135 447.8 0.2 9.9e-135 447.6 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KEY70010.1 - 1.8e-82 275.0 2.1 3.2e-82 274.1 1.5 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KEY70010.1 - 1.6e-06 27.3 0.1 3.5e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 KEY70010.1 - 0.0013 18.3 0.1 0.0025 17.4 0.1 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.7 KEY70010.1 - 0.018 14.4 0.5 0.034 13.5 0.3 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 KEY70010.1 - 0.067 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain JAB PF01398.16 KEY70011.1 - 7.9e-07 28.8 0.8 1.5e-05 24.6 0.6 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease STN PF07660.9 KEY70011.1 - 0.027 14.0 0.1 0.068 12.7 0.0 1.8 1 0 0 1 1 1 0 Secretin and TonB N terminus short domain DDE_1 PF03184.14 KEY70011.1 - 0.037 13.1 0.0 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease Mito_carr PF00153.22 KEY70013.1 - 3.8e-45 151.5 2.6 1.5e-19 69.4 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein SpoIIE PF07228.7 KEY70014.1 - 5.5e-11 42.5 0.2 1.1e-10 41.5 0.2 1.5 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KEY70014.1 - 1.7e-08 34.1 0.1 2.9e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 KEY70014.1 - 8.7e-05 22.0 0.1 0.11 11.8 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C BRO1 PF03097.13 KEY70016.1 - 2.9e-06 26.2 0.0 3.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain Alg6_Alg8 PF03155.10 KEY70017.1 - 4.6e-126 421.3 29.2 1.8e-78 264.5 8.2 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family Ribosomal_60s PF00428.14 KEY70019.1 - 1.9e-28 98.7 11.9 2.1e-28 98.5 8.2 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein SPT2 PF08243.6 KEY70020.1 - 4.8e-08 33.3 22.5 3.9e-06 27.1 15.6 2.6 1 1 0 1 1 1 1 SPT2 chromatin protein NUFIP1 PF10453.4 KEY70021.1 - 1.8e-05 24.1 0.7 5.8e-05 22.5 0.5 1.9 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 KEY70021.1 - 0.14 11.8 5.7 0.29 10.8 4.0 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RNA_pol_Rbc25 PF08292.7 KEY70022.1 - 7.5e-34 116.5 0.0 1e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KEY70022.1 - 3.9e-13 49.3 0.0 5.8e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF106 PF01956.11 KEY70023.1 - 7.7e-56 188.2 1.1 7.7e-56 188.2 0.8 1.4 2 0 0 2 2 2 1 Integral membrane protein DUF106 TatC PF00902.13 KEY70023.1 - 0.17 11.2 5.4 2 7.7 1.1 2.1 2 0 0 2 2 2 0 Sec-independent protein translocase protein (TatC) TPPK_C PF12555.3 KEY70023.1 - 0.18 11.5 2.2 0.3 10.8 0.7 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal SPC25 PF06703.6 KEY70024.1 - 5.4e-53 178.8 0.1 6.4e-53 178.6 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) MMS19_N PF14500.1 KEY70025.1 - 3.1e-44 151.2 0.0 7.6e-44 149.9 0.0 1.6 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 KEY70025.1 - 7.7e-12 44.6 0.1 7.2e-11 41.4 0.0 2.6 2 2 0 2 2 2 1 RNAPII transcription regulator C-terminal ATP11 PF06644.6 KEY70026.1 - 1.1e-76 257.9 0.0 1.3e-76 257.6 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein AMP-binding PF00501.23 KEY70027.1 - 5.2e-95 318.2 0.0 6.2e-95 318.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEY70027.1 - 1.4e-09 38.7 0.1 3e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydro_lipase PF04083.11 KEY70028.1 - 2e-19 68.6 0.1 6.6e-19 67.0 0.0 2.0 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 KEY70028.1 - 0.00013 21.8 0.0 0.00032 20.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Herpes_PAP PF03325.8 KEY70028.1 - 0.014 14.9 0.3 0.025 14.1 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein Abhydrolase_5 PF12695.2 KEY70028.1 - 0.029 14.1 0.0 0.051 13.3 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family AAA PF00004.24 KEY70029.1 - 3.6e-51 172.8 0.0 1.2e-43 148.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEY70029.1 - 7.2e-06 26.8 0.0 0.00044 21.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KEY70029.1 - 4.7e-05 22.8 0.1 0.00044 19.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KEY70029.1 - 0.00021 20.4 0.0 0.0005 19.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Parvo_NS1 PF01057.12 KEY70029.1 - 0.00059 18.7 0.0 0.0011 17.8 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.1 KEY70029.1 - 0.00073 19.6 0.0 0.0038 17.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KEY70029.1 - 0.00091 18.6 0.0 0.0023 17.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 KEY70029.1 - 0.0013 18.7 3.8 0.025 14.5 0.0 3.7 3 1 1 4 4 4 1 AAA ATPase domain AAA_2 PF07724.9 KEY70029.1 - 0.0029 17.5 0.0 0.0073 16.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 KEY70029.1 - 0.0033 17.1 0.0 0.017 14.8 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 KEY70029.1 - 0.0095 16.1 0.0 0.032 14.3 0.0 1.9 2 0 0 2 2 1 1 RNA helicase TIP49 PF06068.8 KEY70029.1 - 0.0097 14.6 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 KEY70029.1 - 0.01 15.5 0.0 0.069 12.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KEY70029.1 - 0.02 14.0 0.1 0.046 12.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 KEY70029.1 - 0.021 14.0 0.0 0.076 12.2 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.1 KEY70029.1 - 0.023 14.5 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KEY70029.1 - 0.036 13.1 0.0 0.071 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.1 KEY70029.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEY70029.1 - 0.075 13.3 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KEY70029.1 - 0.084 12.7 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KEY70029.1 - 0.15 11.6 0.2 0.29 10.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KEY70029.1 - 0.18 11.2 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.8 KEY70029.1 - 0.26 10.1 0.0 0.45 9.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PPV_E1_C PF00519.12 KEY70029.1 - 0.31 9.6 0.0 0.49 8.9 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase TFIIA PF03153.8 KEY70030.1 - 5.1e-06 26.6 30.7 7.6e-06 26.0 21.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SH3BGR PF04908.10 KEY70030.1 - 2e-05 24.4 0.5 0.00027 20.8 0.0 2.9 2 1 1 3 3 3 1 SH3-binding, glutamic acid-rich protein MaoC_dehydratas PF01575.14 KEY70032.1 - 2e-06 27.2 0.0 3.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain Phosphodiest PF01663.17 KEY70033.1 - 5.3e-14 52.3 0.3 1.1e-13 51.3 0.2 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KEY70033.1 - 3.9e-05 22.9 0.0 6.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 KEY70033.1 - 7.7e-05 22.2 0.3 0.00013 21.4 0.2 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Cytochrom_B561 PF03188.11 KEY70034.1 - 0.00027 20.7 9.2 0.0005 19.9 6.4 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 KEY70034.1 - 0.013 15.1 3.5 0.025 14.1 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) DUF4131 PF13567.1 KEY70034.1 - 0.69 9.3 5.9 8.1 5.8 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Zn_clus PF00172.13 KEY70035.1 - 2.8e-09 36.7 5.0 5.6e-09 35.7 3.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY70035.1 - 2.3e-07 29.9 0.0 8e-07 28.1 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain HeLo PF14479.1 KEY70036.1 - 4.3e-37 127.9 8.9 5.2e-37 127.6 4.0 2.4 2 0 0 2 2 2 1 Prion-inhibition and propagation Pkinase PF00069.20 KEY70036.1 - 9.1e-05 21.7 0.0 0.00021 20.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY70036.1 - 0.00035 19.7 0.2 0.0015 17.6 0.2 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KEY70037.1 - 3e-39 134.7 0.0 4.4e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY70037.1 - 6.2e-28 97.5 0.0 9.2e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEY70037.1 - 0.00083 19.1 0.0 1.5 8.5 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KEY70037.1 - 0.02 13.9 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KEY70037.1 - 0.037 12.9 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like WD40 PF00400.27 KEY70038.1 - 4e-16 58.1 0.5 0.00044 20.0 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 KEY70038.1 - 0.067 11.3 0.0 0.23 9.5 0.0 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 INSIG PF07281.7 KEY70039.1 - 2e-47 161.0 0.4 2.5e-47 160.7 0.3 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) Zn_clus PF00172.13 KEY70040.1 - 5.8e-09 35.7 7.9 5.8e-09 35.7 5.5 2.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Closter_coat PF01785.12 KEY70042.1 - 0.016 14.2 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Closterovirus coat protein E1-E2_ATPase PF00122.15 KEY70044.1 - 7.5e-48 162.5 0.0 1.4e-46 158.3 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KEY70044.1 - 9.8e-43 147.0 0.1 1.7e-42 146.2 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KEY70044.1 - 1.2e-33 115.0 0.1 1e-10 41.6 0.1 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 KEY70044.1 - 6.5e-17 62.3 0.0 1.2e-16 61.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEY70044.1 - 0.0038 16.8 0.2 0.012 15.2 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Peripla_BP_3 PF13377.1 KEY70044.1 - 0.019 14.9 0.0 0.074 13.0 0.0 2.0 2 0 0 2 2 2 0 Periplasmic binding protein-like domain POTRA_1 PF08478.5 KEY70044.1 - 0.037 14.0 0.0 22 5.1 0.0 3.6 3 0 0 3 3 3 0 POTRA domain, FtsQ-type GFA PF04828.9 KEY70044.1 - 0.084 12.8 5.6 2 8.4 0.7 3.7 3 1 1 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme Cu-oxidase_2 PF07731.9 KEY70045.1 - 2.5e-42 143.6 6.8 6.1e-34 116.4 2.2 4.0 4 0 0 4 4 4 3 Multicopper oxidase Cu-oxidase_3 PF07732.10 KEY70045.1 - 2e-26 92.0 0.0 2e-26 92.0 0.0 3.3 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 KEY70045.1 - 3.3e-18 66.0 0.2 5.2e-13 49.1 0.0 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cytadhesin_P30 PF07271.6 KEY70045.1 - 2.7 7.1 8.4 5.6 6.1 5.7 1.5 1 1 0 1 1 1 0 Cytadhesin P30/P32 tRNA-synt_2 PF00152.15 KEY70046.1 - 3.8e-47 160.7 0.0 5.6e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KEY70046.1 - 2.2e-06 27.4 0.0 4.8e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain DUF4539 PF15072.1 KEY70046.1 - 0.035 13.7 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) Zip PF02535.17 KEY70047.1 - 2e-51 174.9 11.3 2.3e-51 174.7 7.8 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter gpUL132 PF11359.3 KEY70047.1 - 0.057 12.7 0.0 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 Glycoprotein UL132 Ank_2 PF12796.2 KEY70049.1 - 0.0024 18.2 0.1 0.49 10.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Sterol-sensing PF12349.3 KEY70049.1 - 0.0084 15.5 0.3 0.39 10.1 0.1 2.4 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Glyco_hydro_18 PF00704.23 KEY70050.1 - 3.5e-17 62.8 4.5 2.6e-16 60.0 3.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KEY70050.1 - 5.1e-05 23.0 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 LysM domain LRRNT_2 PF08263.7 KEY70050.1 - 3 7.8 7.6 0.3 11.0 0.8 2.7 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain Fringe PF02434.11 KEY70052.1 - 2.7e-06 26.7 0.1 2.5e-05 23.6 0.1 2.2 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.21 KEY70052.1 - 0.00015 21.4 0.1 0.00026 20.6 0.1 1.3 1 0 0 1 1 1 1 PAN domain Galactosyl_T PF01762.16 KEY70052.1 - 0.037 13.6 0.1 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Galactosyltransferase UCH PF00443.24 KEY70053.1 - 3.4e-44 150.9 0.0 3.7e-38 131.1 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEY70053.1 - 7e-12 45.3 0.0 6.8e-07 29.0 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase F-box-like PF12937.2 KEY70055.1 - 0.0014 18.3 0.2 0.0014 18.3 0.2 2.1 2 0 0 2 2 2 1 F-box-like ATG11 PF10377.4 KEY70056.1 - 9.9e-39 132.1 0.3 9.9e-39 132.1 0.2 3.2 3 0 0 3 3 2 1 Autophagy-related protein 11 WEMBL PF05701.6 KEY70056.1 - 2.5e-05 22.9 35.1 2.5e-05 22.9 24.3 4.5 5 2 1 6 6 6 1 Weak chloroplast movement under blue light Cleaved_Adhesin PF07675.6 KEY70056.1 - 5.9e-05 22.7 0.1 0.00015 21.3 0.0 1.6 1 0 0 1 1 1 1 Cleaved Adhesin Domain APG17 PF04108.7 KEY70056.1 - 0.00021 20.2 0.6 0.00021 20.2 0.4 5.6 4 1 1 5 5 4 1 Autophagy protein Apg17 AAA_13 PF13166.1 KEY70056.1 - 0.0022 16.5 18.8 0.0022 16.5 13.0 5.2 3 1 2 5 5 5 2 AAA domain CENP-F_leu_zip PF10473.4 KEY70056.1 - 0.003 17.4 24.2 0.003 17.4 16.7 7.2 7 2 1 8 8 8 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 KEY70056.1 - 0.0034 17.0 24.0 0.0034 17.0 16.6 6.6 3 1 2 6 6 6 2 IncA protein Pox_A_type_inc PF04508.7 KEY70056.1 - 0.071 12.9 0.0 0.071 12.9 0.0 7.3 9 0 0 9 9 8 0 Viral A-type inclusion protein repeat Fusion_gly PF00523.13 KEY70056.1 - 1.1 7.2 3.0 0.91 7.5 0.2 2.0 2 0 0 2 2 2 0 Fusion glycoprotein F0 EzrA PF06160.7 KEY70056.1 - 1.5 6.9 63.5 0.14 10.2 28.9 4.9 3 2 1 4 4 4 0 Septation ring formation regulator, EzrA Spc7 PF08317.6 KEY70056.1 - 7.9 5.0 78.0 0.038 12.6 5.4 7.2 4 1 1 7 7 7 0 Spc7 kinetochore protein ADIP PF11559.3 KEY70056.1 - 8.9 6.1 82.2 0.34 10.7 5.6 8.6 5 2 3 8 8 8 0 Afadin- and alpha -actinin-Binding CENP-H PF05837.7 KEY70057.1 - 6e-23 81.0 5.0 7e-23 80.8 0.1 2.6 2 1 0 2 2 2 1 Centromere protein H (CENP-H) Mito_fiss_reg PF05308.6 KEY70057.1 - 0.035 13.4 1.7 0.081 12.2 0.0 2.1 2 1 0 2 2 2 0 Mitochondrial fission regulator DUF972 PF06156.8 KEY70057.1 - 0.054 13.8 3.5 0.074 13.4 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.3 KEY70057.1 - 0.91 9.2 7.9 0.15 11.8 2.6 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 KEY70057.1 - 5.3 6.9 6.9 0.87 9.4 0.1 2.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding HMG_box PF00505.14 KEY70058.1 - 5.1e-25 87.5 0.7 8.7e-25 86.7 0.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KEY70058.1 - 1.9e-18 66.5 1.5 1.9e-18 66.5 1.1 1.9 1 1 1 2 2 2 1 HMG-box domain HMG_box_5 PF14887.1 KEY70058.1 - 0.0017 18.1 0.9 0.0035 17.0 0.6 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 KEY70058.1 - 0.02 15.0 1.2 0.042 14.0 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) Prp31_C PF09785.4 KEY70058.1 - 0.2 12.1 3.0 0.22 11.9 2.1 1.1 1 0 0 1 1 1 0 Prp31 C terminal domain DEADboxA PF12343.3 KEY70058.1 - 0.23 11.7 1.7 0.78 10.0 1.2 1.9 1 1 0 1 1 1 0 Cold shock protein DEAD box A PGM_PMM_I PF02878.11 KEY70060.1 - 1.2e-32 112.3 0.0 1.8e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KEY70060.1 - 1.1e-24 86.5 0.0 1.9e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 KEY70060.1 - 4.4e-16 59.1 0.1 8.7e-16 58.1 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KEY70060.1 - 9.9e-08 31.8 0.0 2.2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.19 KEY70061.1 - 2.3e-25 89.7 0.0 2.7e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Exonuclease GFO_IDH_MocA PF01408.17 KEY70062.1 - 2e-12 47.6 0.0 3.8e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KEY70062.1 - 6.8e-05 22.6 0.1 0.00017 21.3 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain AlaDh_PNT_C PF01262.16 KEY70062.1 - 0.024 14.1 0.0 0.054 13.0 0.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain SKG6 PF08693.5 KEY70063.1 - 0.0028 16.9 0.9 0.0048 16.1 0.7 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain PDGLE PF13190.1 KEY70063.1 - 0.0036 16.9 0.2 0.0061 16.2 0.2 1.4 1 0 0 1 1 1 1 PDGLE domain DUF1191 PF06697.7 KEY70063.1 - 0.0043 15.9 0.0 0.0043 15.9 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1191) Protocadherin PF08374.6 KEY70063.1 - 0.0059 16.2 0.0 0.0088 15.7 0.0 1.2 1 0 0 1 1 1 1 Protocadherin Syndecan PF01034.15 KEY70063.1 - 0.0073 15.9 1.9 0.014 15.0 1.3 1.4 1 0 0 1 1 1 1 Syndecan domain Ribosomal_S19 PF00203.16 KEY70066.1 - 1.3e-33 114.3 0.3 2.1e-33 113.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 DUF462 PF04315.7 KEY70066.1 - 0.056 12.8 0.0 4.7 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF462 MerR-DNA-bind PF09278.6 KEY70067.1 - 0.043 14.1 0.3 0.078 13.3 0.2 1.4 1 0 0 1 1 1 0 MerR, DNA binding Glyco_hydro_53 PF07745.8 KEY70068.1 - 7.6e-109 363.5 0.0 8.6e-109 363.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Tubulin PF00091.20 KEY70069.1 - 4e-59 200.0 0.0 4.7e-58 196.5 0.0 2.0 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KEY70069.1 - 3.7e-43 146.5 0.0 6.1e-43 145.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KEY70069.1 - 0.0013 18.2 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.17 KEY70070.1 - 4.7e-15 54.9 0.2 7.3e-10 38.3 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY70070.1 - 5.4e-12 45.5 0.0 3e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY70070.1 - 6.2e-12 45.1 0.0 1.9e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Daxx PF03344.10 KEY70070.1 - 0.00042 18.9 20.8 0.00065 18.3 14.4 1.3 1 0 0 1 1 1 1 Daxx Family RNA_pol_Rpc4 PF05132.9 KEY70070.1 - 0.3 11.0 0.1 0.3 11.0 0.0 4.2 2 1 0 2 2 2 0 RNA polymerase III RPC4 Sds3 PF08598.6 KEY70071.1 - 1.5e-15 57.2 7.8 1.5e-15 57.2 5.4 3.7 2 2 0 2 2 2 1 Sds3-like DIT1_PvcA PF05141.7 KEY70071.1 - 0.44 9.8 4.3 0.74 9.0 3.0 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Coiled-coil_56 PF09813.4 KEY70072.1 - 3.3e-06 27.0 0.0 3.4e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.3 KEY70073.1 - 2.2e-61 207.3 0.0 4.4e-61 206.3 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) NRN1 PF15056.1 KEY70074.1 - 0.0093 15.8 0.1 0.036 14.0 0.0 2.0 1 1 1 2 2 2 1 Neuritin protein family DUF3990 PF13151.1 KEY70074.1 - 0.62 9.4 4.3 1.3 8.3 3.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3990) YlqD PF11068.3 KEY70074.1 - 5 7.1 34.3 0.88 9.6 10.6 3.0 1 1 2 3 3 3 0 YlqD protein 3Beta_HSD PF01073.14 KEY70076.1 - 2.8e-29 101.7 0.0 4.5e-14 51.8 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KEY70076.1 - 2.2e-12 46.9 0.0 5.8e-12 45.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KEY70076.1 - 3.6e-09 35.9 0.0 2.8e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 KEY70076.1 - 4.8e-06 26.5 2.5 1.7e-05 24.7 1.8 2.0 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KEY70076.1 - 6e-06 26.3 0.5 5.2e-05 23.3 0.3 2.3 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KEY70076.1 - 0.005 15.7 0.2 0.67 8.7 0.1 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein KR PF08659.5 KEY70076.1 - 0.012 15.3 1.6 0.064 12.9 1.1 2.3 1 1 0 1 1 1 0 KR domain ThiF PF00899.16 KEY70076.1 - 0.072 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 ThiF family F420_oxidored PF03807.12 KEY70076.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KEY70076.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain K_oxygenase PF13434.1 KEY70076.1 - 0.18 10.6 0.0 0.35 9.7 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fungal_trans PF04082.13 KEY70077.1 - 8.5e-14 51.0 0.0 1.4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KEY70079.1 - 2.1e-29 102.3 29.7 2.1e-29 102.3 20.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY70079.1 - 0.00022 19.9 20.4 0.00022 19.9 14.2 3.6 2 2 1 3 3 3 1 Sugar (and other) transporter DUF4022 PF13214.1 KEY70079.1 - 0.02 14.9 10.5 0.88 9.7 0.4 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF4022) His_Phos_2 PF00328.17 KEY70080.1 - 0.00047 19.5 0.2 2.3 7.4 0.0 3.0 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 2) adh_short PF00106.20 KEY70081.1 - 5.5e-23 81.7 1.7 7.4e-23 81.2 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY70081.1 - 5.1e-20 72.2 0.1 6.5e-20 71.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY70081.1 - 1.1e-11 44.7 0.2 1.5e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Pkinase PF00069.20 KEY70082.1 - 4.8e-69 232.4 0.0 8.1e-69 231.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY70082.1 - 1.3e-38 132.6 0.0 2.1e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY70082.1 - 3.8e-08 32.6 0.0 1e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KEY70082.1 - 0.0035 17.0 0.2 0.026 14.2 0.1 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEY70082.1 - 0.045 12.5 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 dCMP_cyt_deam_1 PF00383.17 KEY70083.1 - 9.5e-16 57.3 0.4 1.3e-15 56.9 0.3 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 KEY70083.1 - 2e-05 24.6 4.5 2.7e-05 24.1 0.6 2.0 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 KEY70083.1 - 4.2e-05 23.0 2.8 0.094 12.0 1.9 2.2 1 1 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases GrpE PF01025.14 KEY70086.1 - 3.6e-51 173.0 4.8 4.5e-51 172.6 3.3 1.1 1 0 0 1 1 1 1 GrpE IncA PF04156.9 KEY70086.1 - 0.19 11.3 3.3 0.35 10.4 2.3 1.5 1 1 0 1 1 1 0 IncA protein Bap31 PF05529.7 KEY70086.1 - 0.7 9.3 3.5 0.7 9.3 1.8 1.5 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like RFC1 PF08519.7 KEY70087.1 - 4.4e-56 188.9 0.0 1e-55 187.7 0.0 1.7 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 KEY70087.1 - 9.9e-14 51.2 0.0 2.1e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 KEY70087.1 - 2.5e-09 37.4 0.2 1.5e-08 34.9 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEY70087.1 - 4.6e-06 26.8 0.0 1.4e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEY70087.1 - 6.5e-05 23.7 1.4 0.00015 22.5 0.0 2.5 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.10 KEY70087.1 - 0.00025 19.8 0.0 0.00049 18.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein DNA_pol3_delta PF06144.8 KEY70087.1 - 0.00027 20.5 0.0 0.00097 18.6 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_19 PF13245.1 KEY70087.1 - 0.0004 20.0 0.1 0.00097 18.8 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 KEY70087.1 - 0.00058 20.1 2.3 0.0013 19.0 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KEY70087.1 - 0.0016 18.0 0.1 0.0036 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEY70087.1 - 0.0032 17.4 0.0 0.053 13.4 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain NACHT PF05729.7 KEY70087.1 - 0.0074 15.9 0.0 1.9 8.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.10 KEY70087.1 - 0.016 14.8 0.0 0.16 11.6 0.0 2.5 3 0 0 3 3 3 0 NTPase AAA_14 PF13173.1 KEY70087.1 - 0.022 14.6 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain PTCB-BRCT PF12738.2 KEY70087.1 - 0.024 14.5 0.0 0.076 12.8 0.0 1.9 1 0 0 1 1 1 0 twin BRCT domain AAA_33 PF13671.1 KEY70087.1 - 0.07 13.0 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KEY70087.1 - 0.075 12.9 0.0 0.075 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KEY70087.1 - 0.084 11.9 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Selenoprotein_S PF06936.6 KEY70087.1 - 0.29 10.6 8.7 0.4 10.2 2.9 2.8 2 0 0 2 2 2 0 Selenoprotein S (SelS) Ribosomal_L16 PF00252.13 KEY70088.1 - 2.8e-28 98.3 2.5 3.9e-28 97.8 0.2 2.3 2 1 0 2 2 2 1 Ribosomal protein L16p/L10e Rep_fac_C PF08542.6 KEY70088.1 - 2.6e-22 78.6 0.1 7.2e-22 77.1 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KEY70088.1 - 1.1e-09 38.1 0.1 2.3e-09 37.1 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 KEY70088.1 - 7.8e-06 26.0 0.5 0.00012 22.2 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 KEY70088.1 - 8.3e-06 26.0 0.0 1.9e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEY70088.1 - 0.0033 17.4 1.9 0.43 10.5 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 KEY70088.1 - 0.0071 16.2 0.1 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KEY70088.1 - 0.052 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.1 KEY70088.1 - 0.053 13.5 0.2 0.24 11.4 0.1 2.2 1 1 1 2 2 2 0 Sigma-54 interaction domain DUF2861 PF11060.3 KEY70088.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2861) T4SS-DNA_transf PF02534.9 KEY70088.1 - 0.1 11.1 0.0 0.21 10.1 0.0 1.5 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer AMP-binding PF00501.23 KEY70089.1 - 1.1e-86 290.8 0.1 1.4e-86 290.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEY70089.1 - 1.8e-22 80.0 0.9 2.4e-20 73.2 0.3 2.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Reprolysin_5 PF13688.1 KEY70090.1 - 8.1e-59 198.8 3.1 8.1e-59 198.8 2.2 2.3 3 0 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KEY70090.1 - 8.9e-45 152.7 0.2 8.9e-45 152.7 0.2 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KEY70090.1 - 1.8e-42 145.3 2.7 3.6e-42 144.3 1.9 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KEY70090.1 - 3.1e-17 63.2 1.1 3.1e-17 63.2 0.8 2.9 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 KEY70090.1 - 1.3e-16 60.5 34.2 1.3e-16 60.5 23.7 4.6 2 1 0 3 3 3 1 Disintegrin Pep_M12B_propep PF01562.14 KEY70090.1 - 0.0022 17.7 0.3 0.0067 16.2 0.1 1.8 2 0 0 2 2 2 1 Reprolysin family propeptide Peptidase_M66 PF10462.4 KEY70090.1 - 0.039 12.8 0.4 0.086 11.7 0.3 1.5 1 0 0 1 1 1 0 Peptidase M66 HxxPF_rpt PF13745.1 KEY70090.1 - 0.083 13.2 0.0 1 9.7 0.0 2.3 2 0 0 2 2 2 0 HxxPF-repeated domain Peptidase_M64 PF09471.5 KEY70090.1 - 0.7 9.4 1.9 2.8 7.5 0.7 2.0 2 0 0 2 2 2 0 IgA Peptidase M64 WD40 PF00400.27 KEY70092.1 - 4.3e-14 51.7 7.4 1e-05 25.2 0.0 7.5 7 1 0 7 7 7 2 WD domain, G-beta repeat LisH PF08513.6 KEY70092.1 - 6.8e-07 28.8 0.1 1.2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 KEY70092.1 - 0.041 13.5 0.2 11 5.6 0.0 3.7 3 1 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KEY70092.1 - 0.056 11.2 0.0 0.26 9.0 0.0 1.8 2 0 0 2 2 2 0 IKI3 family DUF1751 PF08551.5 KEY70093.1 - 5.6e-25 87.5 7.7 9.4e-25 86.8 5.3 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 KEY70093.1 - 0.15 12.0 11.4 0.29 11.1 7.9 1.4 1 0 0 1 1 1 0 Rhomboid family TPR_11 PF13414.1 KEY70094.1 - 8.2e-50 166.3 44.5 2.9e-14 52.4 1.1 7.2 3 3 6 9 9 9 9 TPR repeat TPR_1 PF00515.23 KEY70094.1 - 5.7e-49 161.8 34.9 4.2e-08 32.4 0.0 10.9 12 1 0 12 12 12 9 Tetratricopeptide repeat TPR_2 PF07719.12 KEY70094.1 - 4e-43 141.8 24.6 8.8e-06 25.2 0.0 10.5 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.1 KEY70094.1 - 2.5e-33 111.3 25.4 1.1e-05 24.8 0.7 10.6 8 1 2 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 KEY70094.1 - 8.4e-33 112.3 17.1 2.1e-08 34.6 0.3 6.7 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 KEY70094.1 - 2.7e-28 97.7 26.5 1.3e-06 28.2 0.2 7.6 4 2 4 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.1 KEY70094.1 - 4e-27 92.2 15.8 0.00022 21.5 0.0 9.4 4 3 5 9 9 9 7 Tetratricopeptide repeat TPR_17 PF13431.1 KEY70094.1 - 7e-27 91.3 17.7 0.001 19.0 0.1 10.2 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 KEY70094.1 - 1.2e-20 73.5 22.2 2.6e-05 24.4 0.2 7.4 5 3 1 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 KEY70094.1 - 2.2e-20 70.7 11.1 0.002 17.7 0.0 9.7 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 KEY70094.1 - 1.4e-19 69.1 18.3 0.0077 16.6 0.0 10.0 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 KEY70094.1 - 7.8e-13 48.0 10.9 0.00078 19.2 0.1 6.4 2 1 5 7 7 7 6 Tetratricopeptide repeat Apc3 PF12895.2 KEY70094.1 - 6.5e-11 42.2 19.2 3.4e-08 33.4 2.2 5.0 4 2 1 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KEY70094.1 - 1.6e-09 37.2 10.5 0.0089 15.1 1.0 5.4 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_20 PF14561.1 KEY70094.1 - 0.00021 21.3 1.8 0.32 11.1 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.4 KEY70094.1 - 0.0004 20.3 15.5 0.00054 19.9 1.4 4.7 5 1 0 6 6 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEY70094.1 - 0.0057 16.4 2.5 9.8 6.1 0.0 4.8 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat DUF2225 PF09986.4 KEY70094.1 - 0.0075 15.7 5.7 0.07 12.5 0.3 3.4 2 2 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.1 KEY70094.1 - 0.02 14.8 18.2 2.6 8.0 0.0 6.9 7 0 0 7 7 6 0 Tetratricopeptide repeat FAT PF02259.18 KEY70094.1 - 0.05 12.5 9.2 0.54 9.1 0.1 3.1 2 2 0 2 2 2 0 FAT domain MIT PF04212.13 KEY70094.1 - 5.5 6.9 15.7 2.1 8.2 0.1 5.4 5 2 0 5 5 5 0 MIT (microtubule interacting and transport) domain Ribosomal_L3 PF00297.17 KEY70095.1 - 5.4e-117 389.8 7.4 6.5e-117 389.5 5.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Chorismate_bind PF00425.13 KEY70097.1 - 5.4e-89 297.9 0.0 4.2e-88 295.0 0.0 2.0 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 KEY70097.1 - 2e-28 99.1 1.6 4.4e-25 88.3 0.0 3.7 2 2 1 3 3 3 2 Anthranilate synthase component I, N terminal region IMS PF00817.15 KEY70099.1 - 4.1e-38 130.5 0.0 6.1e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KEY70099.1 - 1.7e-09 37.6 0.0 3.7e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF726 PF05277.7 KEY70100.1 - 4.5e-93 311.8 0.0 7.3e-93 311.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DENN PF02141.16 KEY70101.1 - 5.8e-58 195.6 0.0 9.5e-58 194.9 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KEY70101.1 - 6.7e-18 64.4 0.0 1.4e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 KEY70101.1 - 1.1e-16 60.6 1.1 2.9e-16 59.2 0.6 1.9 2 0 0 2 2 2 1 dDENN domain SPA PF08616.5 KEY70101.1 - 0.032 13.9 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis PHD PF00628.24 KEY70101.1 - 0.035 13.7 4.3 0.09 12.4 3.0 1.7 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.17 KEY70101.1 - 0.18 11.5 7.7 0.4 10.4 5.3 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 KEY70101.1 - 0.2 11.7 3.6 0.42 10.6 2.5 1.6 1 0 0 1 1 1 0 C1-like domain C1_2 PF03107.11 KEY70101.1 - 0.79 9.8 4.5 1.4 9.1 3.1 1.4 1 0 0 1 1 1 0 C1 domain zf-HIT PF04438.11 KEY70101.1 - 1.5 8.5 3.6 2.6 7.7 2.5 1.3 1 0 0 1 1 1 0 HIT zinc finger HTH_Tnp_Tc5 PF03221.11 KEY70102.1 - 3e-06 26.9 1.1 1.1e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 KEY70102.1 - 0.00076 18.6 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease NACHT PF05729.7 KEY70103.1 - 1.8e-06 27.7 0.0 2.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 KEY70103.1 - 6.8e-05 21.8 0.0 0.024 13.4 0.0 2.1 2 0 0 2 2 2 2 NB-ARC domain AAA_22 PF13401.1 KEY70103.1 - 0.0018 18.4 0.0 0.0033 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEY70103.1 - 0.003 16.9 0.0 0.0089 15.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEY70103.1 - 0.011 15.6 0.1 0.59 10.0 0.1 2.3 1 1 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 KEY70103.1 - 0.028 14.1 0.0 4.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase DUF3759 PF12585.3 KEY70106.1 - 2e-36 123.7 4.4 2.7e-36 123.3 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) adh_short PF00106.20 KEY70107.1 - 7.5e-15 55.2 1.2 2.2e-14 53.7 0.4 2.0 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY70107.1 - 2.8e-07 30.5 0.1 3.7e-07 30.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY70107.1 - 8.4e-07 28.8 0.0 2.5e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KEY70107.1 - 5.1e-05 22.8 0.0 0.00013 21.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.8 KEY70109.1 - 3e-39 134.7 0.1 3.7e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEY70109.1 - 1.6e-08 34.7 0.6 2.6e-08 34.0 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEY70109.1 - 0.00013 21.2 0.0 0.0012 18.1 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 KEY70109.1 - 0.00017 20.9 0.0 0.0043 16.3 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KEY70109.1 - 0.00053 19.7 0.0 0.00074 19.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KEY70109.1 - 0.00076 18.9 0.0 0.0026 17.2 0.0 1.7 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 KEY70109.1 - 0.0014 18.1 0.2 0.041 13.3 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Lipase_3 PF01764.20 KEY70109.1 - 0.0053 16.3 0.0 0.0093 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 KEY70109.1 - 0.0069 15.7 0.0 0.0097 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) AXE1 PF05448.7 KEY70109.1 - 0.029 12.8 0.0 0.045 12.2 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 KEY70109.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PAE PF03283.8 KEY70109.1 - 0.22 10.1 0.0 0.31 9.6 0.0 1.1 1 0 0 1 1 1 0 Pectinacetylesterase Esterase_phd PF10503.4 KEY70109.1 - 0.39 9.9 2.2 0.28 10.4 0.2 1.6 2 0 0 2 2 2 0 Esterase PHB depolymerase p450 PF00067.17 KEY70110.1 - 2.3e-70 237.4 0.0 9.8e-69 232.0 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 KEY70110.1 - 5.9e-33 114.1 0.0 9.8e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KEY70110.1 - 1.3e-26 93.2 0.0 2.6e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KEY70110.1 - 5.8e-15 55.7 0.0 1.6e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KEY70110.1 - 0.051 13.5 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain Flavodoxin_NdrI PF07972.6 KEY70110.1 - 0.19 11.6 0.0 0.47 10.3 0.0 1.7 1 0 0 1 1 1 0 NrdI Flavodoxin like SRP54 PF00448.17 KEY70111.1 - 6.3e-77 257.4 1.1 6.3e-77 257.4 0.8 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KEY70111.1 - 3.9e-25 88.0 5.8 3.9e-25 88.0 4.1 4.2 3 2 2 5 5 3 1 Signal peptide binding domain SRP54_N PF02881.14 KEY70111.1 - 1.9e-15 56.7 0.3 4.9e-15 55.3 0.2 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 KEY70111.1 - 1e-08 34.8 0.1 3.1e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KEY70111.1 - 1.9e-07 31.0 0.1 7.4e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KEY70111.1 - 1.9e-05 24.4 0.0 6.4e-05 22.6 0.0 1.9 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 KEY70111.1 - 3.5e-05 23.2 0.1 0.00013 21.4 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 KEY70111.1 - 3.7e-05 24.5 0.0 8.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEY70111.1 - 0.00018 20.6 0.0 0.00039 19.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_31 PF13614.1 KEY70111.1 - 0.00044 20.2 0.0 1.3 8.8 0.0 2.8 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 KEY70111.1 - 0.00079 19.4 0.1 0.0019 18.1 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain APS_kinase PF01583.15 KEY70111.1 - 0.002 17.8 0.0 0.0038 16.8 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase ArgK PF03308.11 KEY70111.1 - 0.0022 16.8 0.3 0.0022 16.8 0.2 2.6 2 1 0 2 2 1 1 ArgK protein AAA_22 PF13401.1 KEY70111.1 - 0.0025 17.9 0.0 0.0084 16.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 KEY70111.1 - 0.0031 17.1 0.4 0.036 13.6 0.0 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Thymidylate_kin PF02223.12 KEY70111.1 - 0.0058 16.0 0.2 0.026 13.8 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.1 KEY70111.1 - 0.0067 16.3 0.1 0.015 15.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.5 KEY70111.1 - 0.0074 15.5 0.8 2.2 7.4 0.0 3.2 2 1 0 3 3 3 1 Signal recognition particle receptor beta subunit AAA_18 PF13238.1 KEY70111.1 - 0.0082 16.4 0.0 0.021 15.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KEY70111.1 - 0.011 15.6 0.0 0.12 12.3 0.0 2.6 1 1 1 2 2 2 0 50S ribosome-binding GTPase 6PF2K PF01591.13 KEY70111.1 - 0.015 14.4 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_19 PF13245.1 KEY70111.1 - 0.019 14.6 0.1 0.066 12.9 0.1 2.0 1 0 0 1 1 1 0 Part of AAA domain Torsin PF06309.6 KEY70111.1 - 0.034 14.0 0.0 0.095 12.5 0.0 1.7 1 1 0 1 1 1 0 Torsin Glyco_transf_4 PF13439.1 KEY70111.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 NTPase_1 PF03266.10 KEY70111.1 - 0.1 12.2 1.6 4.9 6.8 1.1 2.3 1 1 0 1 1 1 0 NTPase DUF3786 PF12654.2 KEY70111.1 - 0.11 11.7 0.5 6.9 5.8 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3786) VirE PF05272.6 KEY70111.1 - 0.12 11.8 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E PTPlike_phytase PF14566.1 KEY70111.1 - 0.13 12.2 0.5 7.1 6.6 0.0 3.1 4 0 0 4 4 4 0 Inositol hexakisphosphate AAA_25 PF13481.1 KEY70111.1 - 0.18 11.1 0.9 0.73 9.1 0.1 2.3 2 1 0 2 2 2 0 AAA domain DUF4149 PF13664.1 KEY70112.1 - 1.2e-18 66.9 3.1 2e-18 66.2 2.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4149) SR-25 PF10500.4 KEY70112.1 - 0.027 13.9 17.8 0.046 13.1 12.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SAPS PF04499.10 KEY70112.1 - 0.069 11.7 1.1 0.097 11.2 0.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 KEY70112.1 - 0.32 8.6 2.0 0.43 8.2 1.4 1.1 1 0 0 1 1 1 0 Ycf1 Zip PF02535.17 KEY70112.1 - 0.63 8.9 1.3 1.4 7.8 0.9 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1510 PF07423.6 KEY70112.1 - 4.4 6.6 20.8 6.7 6.0 14.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Formyl_trans_N PF00551.14 KEY70113.1 - 1.6e-37 128.8 0.2 1.9e-37 128.5 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 KEY70113.1 - 9.7e-11 40.9 0.0 8.2e-10 37.9 0.0 2.4 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.1 KEY70113.1 - 7.1e-05 22.4 0.0 0.00045 19.8 0.0 2.2 2 0 0 2 2 2 1 ACT domain Thymidylate_kin PF02223.12 KEY70114.1 - 6.3e-42 143.0 0.0 7.1e-42 142.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 KEY70114.1 - 3.9e-08 33.4 0.0 5.6e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KEY70114.1 - 0.0091 15.2 0.0 0.015 14.4 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 PRK PF00485.13 KEY70114.1 - 0.018 14.5 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Arf PF00025.16 KEY70114.1 - 0.073 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family GATase PF00117.23 KEY70116.1 - 4.6e-36 124.0 0.0 9.9e-36 122.9 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 KEY70116.1 - 1.5e-33 114.3 0.0 4.3e-33 112.8 0.0 1.8 2 0 0 2 2 2 1 GMP synthase C terminal domain NAD_synthase PF02540.12 KEY70116.1 - 1.3e-09 37.3 0.0 1.7e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 KEY70116.1 - 4.7e-08 32.7 0.0 1.4e-07 31.2 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 KEY70116.1 - 0.003 16.1 0.0 0.0062 15.1 0.0 1.5 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.16 KEY70116.1 - 0.0055 16.2 0.1 0.02 14.4 0.0 1.8 2 0 0 2 2 2 1 Asparagine synthase PAPS_reduct PF01507.14 KEY70116.1 - 0.023 14.5 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ThiI PF02568.9 KEY70116.1 - 0.056 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) QueC PF06508.8 KEY70116.1 - 0.081 12.1 0.0 0.49 9.6 0.0 2.0 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Glyco_hydro_11 PF00457.12 KEY70117.1 - 1.1e-55 187.7 9.4 1.4e-55 187.4 6.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Calici_MSP PF05752.6 KEY70117.1 - 0.12 11.9 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 Calicivirus minor structural protein PLAC8 PF04749.12 KEY70118.1 - 2.4e-07 31.2 3.1 3.9e-07 30.5 2.2 1.2 1 0 0 1 1 1 1 PLAC8 family Photo_RC PF00124.14 KEY70120.1 - 0.05 12.6 0.0 0.051 12.5 0.0 1.0 1 0 0 1 1 1 0 Photosynthetic reaction centre protein DUF3040 PF11239.3 KEY70120.1 - 2 8.5 5.4 9.6 6.3 3.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) Ras PF00071.17 KEY70121.1 - 2.6e-31 108.1 0.1 3.4e-31 107.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEY70121.1 - 1.2e-20 74.2 0.1 4.8e-20 72.2 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KEY70121.1 - 2.8e-06 26.6 0.1 3.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEY70121.1 - 0.00019 20.6 0.1 0.00027 20.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KEY70121.1 - 0.14 10.8 0.1 0.33 9.6 0.0 1.6 1 1 1 2 2 2 0 G-protein alpha subunit GCV_H PF01597.14 KEY70122.1 - 2.5e-29 101.4 0.2 3e-29 101.1 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Porphobil_deam PF01379.15 KEY70123.1 - 1.1e-80 269.6 0.0 1.5e-80 269.1 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 KEY70123.1 - 4e-17 62.0 0.1 9.2e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain PNTB PF02233.11 KEY70125.1 - 1.4e-165 551.5 24.5 1.4e-165 551.5 17.0 1.6 2 0 0 2 2 1 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 KEY70125.1 - 8.5e-55 184.8 1.1 1.7e-54 183.8 0.8 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KEY70125.1 - 7.5e-50 168.4 0.2 2.8e-49 166.6 0.0 2.1 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 KEY70125.1 - 3e-31 107.4 4.0 3e-31 107.4 2.8 5.4 4 2 1 6 6 6 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 KEY70125.1 - 0.00036 19.7 0.0 0.68 9.0 0.0 2.6 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.1 KEY70125.1 - 0.0077 15.8 0.0 0.03 13.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Pyr_redox_2 PF07992.9 KEY70125.1 - 0.01 15.7 0.2 0.05 13.4 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KEY70125.1 - 0.038 14.1 8.0 4.7 7.3 0.0 5.1 4 1 1 5 5 5 0 Shikimate / quinate 5-dehydrogenase Methyltransf_18 PF12847.2 KEY70125.1 - 0.047 14.2 0.0 0.14 12.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain GIDA PF01134.17 KEY70125.1 - 0.073 11.9 0.8 0.13 11.1 0.6 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A CP_ATPgrasp_1 PF04174.8 KEY70125.1 - 0.17 10.4 0.0 0.3 9.6 0.0 1.3 1 0 0 1 1 1 0 A circularly permuted ATPgrasp NDUFA12 PF05071.11 KEY70126.1 - 8.2e-23 80.8 0.1 1e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.1 KEY70127.1 - 4.8e-13 48.9 0.0 1.2e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KEY70127.1 - 8.7e-07 28.5 0.8 0.016 15.0 0.2 3.2 2 1 0 2 2 2 2 Phospholipase D Active site motif Ribosomal_L4 PF00573.17 KEY70128.1 - 8e-49 165.6 0.0 1e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PBP PF01161.15 KEY70129.1 - 1.5e-07 31.3 0.0 2.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein bZIP_1 PF00170.16 KEY70130.1 - 3.6e-12 46.0 3.4 3.6e-12 46.0 2.3 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KEY70130.1 - 3.2e-07 30.0 1.6 3.2e-07 30.0 1.1 2.3 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.12 KEY70130.1 - 0.00016 21.9 1.6 0.00016 21.9 1.1 2.5 2 1 0 2 2 2 1 bZIP Maf transcription factor Jnk-SapK_ap_N PF09744.4 KEY70130.1 - 0.074 13.0 3.2 0.13 12.2 2.2 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 V_ATPase_I PF01496.14 KEY70130.1 - 0.2 9.4 0.7 0.25 9.1 0.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2959 PF11172.3 KEY70130.1 - 0.22 11.2 2.2 0.52 10.0 1.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2959) Glyco_hydro_45 PF02015.11 KEY70131.1 - 9.6e-87 290.2 16.4 1.1e-86 290.0 11.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Peptidase_M20 PF01546.23 KEY70132.1 - 7.3e-30 103.8 0.1 9.9e-30 103.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 KEY70132.1 - 0.00012 21.9 0.0 0.00026 20.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.9 KEY70132.1 - 0.026 14.2 0.0 0.07 12.8 0.0 1.8 1 1 0 1 1 1 0 Peptidase dimerisation domain FMO-like PF00743.14 KEY70133.1 - 1.3e-61 208.4 0.0 1.6e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KEY70133.1 - 3.9e-24 85.8 0.0 6.9e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEY70133.1 - 8.3e-11 42.1 0.0 9.7e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEY70133.1 - 1.3e-09 37.9 0.1 7e-08 32.4 0.0 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KEY70133.1 - 1.2e-08 34.8 0.0 2.8e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KEY70133.1 - 4.7e-05 22.5 0.0 0.0001 21.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KEY70133.1 - 5.8e-05 22.1 0.2 0.00052 19.0 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 KEY70133.1 - 0.0001 21.3 0.9 0.0013 17.7 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KEY70133.1 - 0.00055 18.5 0.0 0.0021 16.6 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KEY70133.1 - 0.0019 17.0 0.1 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KEY70133.1 - 0.0025 18.1 0.2 0.15 12.4 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEY70133.1 - 0.0028 16.7 0.0 0.0045 16.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain UDPG_MGDP_dh_N PF03721.9 KEY70133.1 - 0.0066 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 KEY70133.1 - 0.014 15.5 0.0 0.33 11.2 0.0 2.6 3 0 0 3 3 3 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 KEY70133.1 - 0.018 15.0 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 NADH(P)-binding Amino_oxidase PF01593.19 KEY70133.1 - 0.05 12.6 0.0 2.1 7.3 0.0 2.7 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Shikimate_DH PF01488.15 KEY70133.1 - 0.084 12.9 0.0 1.8 8.6 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase XdhC_C PF13478.1 KEY70133.1 - 0.086 13.1 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain 3HCDH_N PF02737.13 KEY70133.1 - 0.086 12.4 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KEY70133.1 - 0.34 10.6 1.4 1.1 9.0 0.1 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Cellulase PF00150.13 KEY70135.1 - 2.5e-20 72.8 3.3 3.4e-20 72.4 2.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 KEY70135.1 - 1.3e-08 34.1 0.0 1.6e-07 30.5 0.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase-like PF12876.2 KEY70135.1 - 2.6e-07 31.0 0.0 6.9e-07 29.6 0.0 1.8 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 KEY70135.1 - 0.0003 20.0 0.1 0.00078 18.6 0.0 1.6 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_61 PF03443.9 KEY70136.1 - 6.5e-50 169.9 0.0 9.4e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 A2M_N PF01835.14 KEY70136.1 - 0.037 14.2 0.0 0.064 13.5 0.0 1.5 1 0 0 1 1 1 0 MG2 domain Glyoxalase_2 PF12681.2 KEY70137.1 - 1.7e-08 35.0 0.1 2.2e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KEY70137.1 - 4.6e-05 23.4 0.2 6.3e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HET PF06985.6 KEY70138.1 - 2.9e-25 89.0 0.0 1.5e-24 86.7 0.0 2.2 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF3718 PF12514.3 KEY70138.1 - 0.049 13.6 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3718) DUF2342 PF10103.4 KEY70138.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2342) Podoplanin PF05808.6 KEY70139.1 - 1.3e-06 28.0 2.2 3.5e-06 26.6 1.5 1.7 1 0 0 1 1 1 1 Podoplanin DUF347 PF03988.7 KEY70139.1 - 0.017 14.9 0.5 0.035 13.9 0.3 1.5 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Adeno_E3_CR2 PF02439.10 KEY70139.1 - 0.16 11.5 0.2 0.16 11.5 0.1 1.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Mucin PF01456.12 KEY70139.1 - 0.75 9.5 23.5 0.038 13.7 12.0 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein PBP PF01161.15 KEY70141.1 - 5.2e-13 49.0 0.5 7e-13 48.6 0.4 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pheromone PF08015.6 KEY70141.1 - 0.018 15.8 0.0 0.049 14.4 0.0 1.8 1 0 0 1 1 1 0 Fungal mating-type pheromone ADH_zinc_N PF00107.21 KEY70142.1 - 1.3e-23 82.9 2.0 2.5e-23 82.0 1.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY70142.1 - 1.4e-15 56.9 0.1 3.4e-15 55.7 0.1 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KEY70142.1 - 2e-13 51.3 0.2 4.8e-13 50.1 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KEY70142.1 - 0.013 15.0 2.2 0.04 13.4 0.0 2.6 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 KEY70142.1 - 0.16 11.0 0.6 0.39 9.8 0.1 1.8 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans PF04082.13 KEY70143.1 - 6.9e-12 44.7 0.4 1.1e-11 44.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KEY70143.1 - 6.2e-07 29.3 11.4 0.0034 17.6 4.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY70143.1 - 0.0014 18.8 16.0 0.0059 16.8 4.0 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEY70143.1 - 0.0042 17.3 4.5 0.0042 17.3 3.2 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 KEY70143.1 - 0.07 13.3 0.7 0.61 10.3 1.0 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Pribosyl_synth PF14572.1 KEY70144.1 - 6.9e-40 136.7 0.5 1.8e-35 122.3 0.1 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KEY70144.1 - 2.3e-30 104.6 0.0 4.8e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KEY70144.1 - 5.1e-12 45.6 0.1 1.3e-11 44.2 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KEY70144.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase AviRa PF11599.3 KEY70144.1 - 0.053 12.5 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 RRNA methyltransferase AviRa F-box-like PF12937.2 KEY70147.1 - 0.0016 18.0 0.0 0.0053 16.4 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KEY70147.1 - 0.0019 17.9 2.4 1.5 8.6 0.0 3.8 3 2 1 4 4 4 2 Leucine rich repeat Peptidase_M14 PF00246.19 KEY70148.1 - 2.9e-74 250.1 0.0 3.8e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 KEY70148.1 - 2.4e-06 27.1 0.0 1.1e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Carboxypeptidase activation peptide ChW PF07538.6 KEY70148.1 - 0.1 12.1 0.2 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 Clostridial hydrophobic W Response_reg PF00072.19 KEY70150.1 - 6.1e-23 80.9 0.2 1.1e-22 80.1 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 KEY70150.1 - 2.7e-19 68.8 0.0 5e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 KEY70150.1 - 7.8e-11 42.2 0.0 1.8e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 PAS domain HisKA PF00512.20 KEY70150.1 - 7.8e-08 32.2 3.1 3.1e-07 30.2 0.0 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.5 KEY70150.1 - 0.00013 21.9 0.0 0.00068 19.6 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.1 KEY70150.1 - 0.00027 20.6 0.0 0.00081 19.1 0.0 1.8 1 0 0 1 1 1 1 PAS domain GAF_2 PF13185.1 KEY70150.1 - 0.0063 17.0 0.0 0.051 14.0 0.0 2.5 2 0 0 2 2 2 1 GAF domain PAS PF00989.19 KEY70150.1 - 0.014 15.1 0.0 0.036 13.8 0.0 1.8 1 0 0 1 1 1 0 PAS fold PAS_3 PF08447.6 KEY70150.1 - 0.016 15.3 0.1 0.038 14.0 0.1 1.6 1 0 0 1 1 1 0 PAS fold GAF_3 PF13492.1 KEY70150.1 - 0.048 13.7 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 GAF domain Peptidase_S8 PF00082.17 KEY70151.1 - 1e-42 146.2 14.7 1e-42 146.2 10.2 1.5 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 KEY70151.1 - 9.4e-14 51.7 0.6 1.8e-13 50.8 0.4 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Chromo PF00385.19 KEY70152.1 - 9.8e-07 28.3 3.8 0.0048 16.5 0.1 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Bradykinin PF06753.7 KEY70155.1 - 0.041 13.3 0.2 0.11 12.0 0.1 1.7 1 0 0 1 1 1 0 Bradykinin Glyco_hydro_18 PF00704.23 KEY70157.1 - 4.8e-15 55.8 0.3 1.6e-13 50.8 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 Lipase_GDSL_2 PF13472.1 KEY70159.1 - 2.4e-12 47.3 0.2 4.2e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KEY70159.1 - 8.6e-09 35.5 0.0 1.5e-08 34.7 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4646 PF15496.1 KEY70160.1 - 0.046 13.7 1.8 0.074 13.1 0.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4646) DUF2625 PF10946.3 KEY70161.1 - 0.11 11.3 0.1 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF2625 PhaP_Bmeg PF09602.5 KEY70162.1 - 0.076 12.8 0.1 0.076 12.8 0.1 2.6 3 0 0 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) PRTP PF01366.13 KEY70162.1 - 0.097 10.6 13.5 0.33 8.8 2.8 2.0 2 0 0 2 2 2 0 Herpesvirus processing and transport protein DUF1911 PF08929.5 KEY70162.1 - 0.17 12.6 0.3 0.17 12.6 0.2 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1911) DUF3323 PF11796.3 KEY70162.1 - 2.4 7.4 12.2 0.39 9.9 2.6 2.8 2 1 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) HALZ PF02183.13 KEY70163.1 - 0.14 11.8 0.0 0.84 9.4 0.0 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4287 PF14117.1 KEY70164.1 - 0.042 13.5 0.1 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) Ank_2 PF12796.2 KEY70165.1 - 2.4e-31 107.8 5.5 4e-09 36.7 0.1 6.3 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEY70165.1 - 9.1e-21 73.8 5.5 2.5e-08 34.2 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 KEY70165.1 - 1.8e-18 65.3 16.5 9.5e-05 22.0 0.1 8.7 10 0 0 10 10 10 5 Ankyrin repeat Ank_3 PF13606.1 KEY70165.1 - 1.9e-15 55.3 15.0 0.00097 19.1 0.0 10.3 11 2 0 11 11 11 4 Ankyrin repeat Ank_5 PF13857.1 KEY70165.1 - 1.4e-12 47.3 6.1 4.9e-05 23.4 0.1 7.2 5 1 2 7 7 7 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEY70166.1 - 3.6e-93 306.0 14.4 9.6e-15 54.7 0.9 10.4 7 2 5 12 12 12 11 Ankyrin repeats (3 copies) Ank PF00023.25 KEY70166.1 - 4.1e-81 263.0 49.5 8.9e-07 28.4 0.4 20.0 19 1 0 19 19 19 14 Ankyrin repeat Ank_4 PF13637.1 KEY70166.1 - 5.5e-57 189.2 28.1 4.2e-09 36.6 0.1 14.8 8 4 7 15 15 15 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY70166.1 - 2.4e-53 172.7 27.8 6.6e-05 22.7 0.0 19.2 18 1 1 19 19 19 11 Ankyrin repeat Ank_5 PF13857.1 KEY70166.1 - 9.8e-52 171.8 47.4 1.3e-08 34.8 0.0 14.9 9 6 6 16 16 16 9 Ankyrin repeats (many copies) AAA_16 PF13191.1 KEY70166.1 - 0.00028 20.9 2.3 0.017 15.1 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain RVP PF00077.15 KEY70166.1 - 0.0023 17.8 0.0 3.2 7.7 0.0 3.8 3 0 0 3 3 3 1 Retroviral aspartyl protease NB-ARC PF00931.17 KEY70166.1 - 0.012 14.4 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.1 KEY70166.1 - 0.065 13.3 0.0 0.34 11.0 0.0 2.3 1 0 0 1 1 1 0 AAA domain PAT1 PF09770.4 KEY70167.1 - 0.49 8.5 8.6 0.5 8.5 5.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MCPVI PF02993.9 KEY70167.1 - 0.87 9.6 5.1 1.2 9.2 3.5 1.3 1 0 0 1 1 1 0 Minor capsid protein VI Trypan_PARP PF05887.6 KEY70167.1 - 5 6.9 14.1 7.8 6.3 9.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Glyco_hydro_61 PF03443.9 KEY70168.1 - 5.6e-70 235.5 0.0 6.5e-70 235.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 KEY70168.1 - 0.0037 17.2 0.1 0.55 10.3 0.0 2.5 2 0 0 2 2 2 2 NPCBM-associated, NEW3 domain of alpha-galactosidase Mpv17_PMP22 PF04117.7 KEY70170.1 - 1.4e-20 72.6 0.1 3.2e-20 71.5 0.1 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family Amidohydro_3 PF07969.6 KEY70171.1 - 5.6e-54 183.9 1.6 6.5e-54 183.6 1.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KEY70171.1 - 7.2e-10 38.5 0.0 2.3e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KEY70171.1 - 1.3e-05 25.3 2.3 0.0032 17.5 0.0 3.2 2 2 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 KEY70171.1 - 1.3e-05 24.9 0.6 0.054 13.1 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase family RE_XcyI PF09571.5 KEY70171.1 - 0.2 10.4 0.0 1.4 7.6 0.0 2.0 2 0 0 2 2 2 0 XcyI restriction endonuclease APH PF01636.18 KEY70172.1 - 1.9e-11 44.1 0.0 3.6e-11 43.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Ank PF00023.25 KEY70173.1 - 5.7e-10 38.4 0.2 5.8e-05 22.6 0.0 4.1 2 1 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KEY70173.1 - 3.8e-07 30.3 0.2 0.01 16.1 0.0 4.2 2 2 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEY70173.1 - 1.5e-06 27.8 1.0 0.0052 16.9 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.1 KEY70173.1 - 0.0048 17.3 0.1 0.13 12.7 0.0 3.4 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY70173.1 - 0.009 16.2 1.8 0.084 13.1 0.0 3.5 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Cu_amine_oxid PF01179.15 KEY70174.1 - 7.3e-111 370.8 7.0 9.7e-111 370.4 4.8 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 KEY70174.1 - 1.7e-22 79.0 0.1 5e-22 77.5 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 KEY70174.1 - 3.6e-05 23.7 0.0 0.00015 21.7 0.0 2.0 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Ank_2 PF12796.2 KEY70175.1 - 4.3e-25 87.8 2.1 2.2e-10 40.7 0.1 4.5 3 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEY70175.1 - 5.6e-17 60.6 24.4 9.4e-05 22.0 1.1 7.8 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 KEY70175.1 - 8.5e-16 57.9 1.5 0.00013 22.3 0.0 5.9 4 3 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY70175.1 - 1.7e-15 55.5 9.1 0.00011 22.0 0.2 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 KEY70175.1 - 2.1e-10 40.5 7.1 0.0029 17.8 0.0 6.2 5 1 2 7 7 7 2 Ankyrin repeats (many copies) Peptidase_S8 PF00082.17 KEY70176.1 - 4.6e-42 144.1 11.7 6.5e-42 143.6 8.1 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KEY70176.1 - 8.7e-10 39.0 0.1 2.8e-09 37.4 0.1 1.9 2 0 0 2 2 2 1 Peptidase inhibitor I9 TFIID_90kDa PF04494.10 KEY70176.1 - 0.24 11.4 0.0 0.38 10.7 0.0 1.2 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit Form_Nir_trans PF01226.12 KEY70177.1 - 7.9e-78 260.7 17.2 9.1e-78 260.6 12.0 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter PPR_2 PF13041.1 KEY70178.1 - 0.034 14.1 0.7 0.068 13.1 0.5 1.6 1 0 0 1 1 1 0 PPR repeat family SpoVIF PF14069.1 KEY70178.1 - 0.092 12.4 1.7 3.6 7.3 0.1 2.2 2 0 0 2 2 2 0 Stage VI sporulation protein F Relaxase PF03432.9 KEY70178.1 - 0.11 11.8 0.0 0.12 11.7 0.0 1.0 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain XPC-binding PF09280.6 KEY70178.1 - 0.31 10.5 2.0 1.1 8.7 0.5 2.3 2 0 0 2 2 2 0 XPC-binding domain BRX_N PF13713.1 KEY70178.1 - 0.39 10.2 0.1 0.39 10.2 0.1 2.0 2 1 1 3 3 3 0 Transcription factor BRX N-terminal domain HET PF06985.6 KEY70179.1 - 7.1e-32 110.4 0.0 1.4e-31 109.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_6 PF00970.19 KEY70179.1 - 3.8e-09 36.5 0.0 7.8e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 KEY70179.1 - 4.5e-08 33.4 0.0 8.5e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.16 KEY70179.1 - 1.6e-06 28.6 0.0 3.8e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.3 KEY70179.1 - 0.0039 16.8 0.0 0.0078 15.8 0.0 1.5 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.7 KEY70179.1 - 0.1 12.5 0.0 0.38 10.6 0.0 2.0 3 0 0 3 3 3 0 Ferric reductase NAD binding domain Piwi PF02171.12 KEY70180.1 - 2.4e-66 223.7 0.0 3.8e-66 223.1 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KEY70180.1 - 4e-17 61.7 0.0 1.4e-16 59.9 0.0 1.9 2 0 0 2 2 2 1 PAZ domain DUF1785 PF08699.5 KEY70180.1 - 1e-15 56.8 0.4 3e-15 55.3 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) WEMBL PF05701.6 KEY70181.1 - 1.5e-05 23.6 290.3 0.045 12.2 32.8 7.2 1 1 5 6 6 6 5 Weak chloroplast movement under blue light IncA PF04156.9 KEY70181.1 - 0.00047 19.8 211.6 0.0016 18.0 13.3 10.8 1 1 9 10 10 9 4 IncA protein ATG16 PF08614.6 KEY70181.1 - 0.00063 19.6 15.0 0.00063 19.6 10.4 9.2 1 1 8 9 9 9 3 Autophagy protein 16 (ATG16) Tropomyosin PF00261.15 KEY70181.1 - 0.0046 16.0 249.3 0.0076 15.3 10.0 8.4 1 1 6 8 8 7 5 Tropomyosin TMCO5 PF14992.1 KEY70181.1 - 0.005 16.0 14.8 0.005 16.0 10.2 8.0 1 1 9 10 10 5 2 TMCO5 family ADIP PF11559.3 KEY70181.1 - 0.0068 16.3 14.7 0.0068 16.3 10.2 13.9 1 1 15 16 16 15 4 Afadin- and alpha -actinin-Binding DUF3584 PF12128.3 KEY70181.1 - 0.033 11.5 229.3 0.005 14.2 43.1 6.0 1 1 5 6 6 6 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 KEY70181.1 - 0.061 11.9 194.3 0.082 11.5 11.7 9.1 1 1 10 11 11 10 0 Spc7 kinetochore protein Filament PF00038.16 KEY70181.1 - 0.19 11.1 192.2 3 7.2 3.6 8.1 1 1 5 6 6 6 0 Intermediate filament protein rve_3 PF13683.1 KEY70181.1 - 0.86 9.1 2.7 11 5.6 0.0 4.1 3 0 0 3 3 3 0 Integrase core domain Baculo_PEP_C PF04513.7 KEY70181.1 - 1.7 8.4 86.2 0.032 14.0 2.9 10.3 1 1 6 10 10 10 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4250 PF14056.1 KEY70181.1 - 8.4 6.1 14.3 11 5.8 0.2 5.9 5 0 0 5 5 5 0 Domain of unknown function (DUF4250) APH PF01636.18 KEY70182.1 - 8.2e-11 42.0 5.1 1.4e-10 41.3 3.5 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEY70182.1 - 5.9e-05 22.7 0.0 6.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 KEY70182.1 - 0.029 13.5 0.0 0.032 13.3 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.17 KEY70182.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Glyco_transf_8 PF01501.15 KEY70183.1 - 4e-05 23.0 0.8 0.00012 21.5 0.6 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KEY70183.1 - 0.00017 21.0 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative ABC_tran PF00005.22 KEY70184.1 - 7.3e-27 94.3 0.0 1.2e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KEY70184.1 - 6.2e-05 23.0 0.0 0.0082 16.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEY70184.1 - 0.00011 21.6 0.1 0.004 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KEY70184.1 - 0.00069 18.8 0.2 0.0012 18.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KEY70184.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_10 PF12846.2 KEY70184.1 - 0.029 13.8 3.1 0.36 10.2 1.5 2.2 1 1 0 2 2 2 0 AAA-like domain SMC_N PF02463.14 KEY70184.1 - 0.034 13.3 0.2 0.3 10.2 0.1 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KEY70184.1 - 0.035 13.6 0.4 0.073 12.6 0.3 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ArgK PF03308.11 KEY70184.1 - 0.044 12.5 0.4 0.094 11.4 0.3 1.4 1 0 0 1 1 1 0 ArgK protein Miro PF08477.8 KEY70184.1 - 0.057 13.9 0.1 0.11 13.0 0.1 1.4 1 0 0 1 1 1 0 Miro-like protein SbcCD_C PF13558.1 KEY70184.1 - 0.11 12.4 0.1 0.32 10.9 0.0 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 KEY70184.1 - 0.12 11.8 0.4 0.25 10.7 0.2 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 KEY70184.1 - 0.15 12.0 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.1 KEY70184.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 KEY70184.1 - 0.19 10.5 0.2 0.28 9.9 0.1 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) TILa PF12714.2 KEY70184.1 - 0.38 10.5 7.4 0.68 9.7 0.1 2.9 2 1 0 2 2 2 0 TILa domain DUF87 PF01935.12 KEY70184.1 - 1.4 8.6 2.8 2.4 7.9 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 ATP_bind_1 PF03029.12 KEY70184.1 - 2.3 7.6 3.0 4.5 6.7 2.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Fve PF09259.6 KEY70185.1 - 8.1e-42 141.6 0.4 9e-42 141.5 0.3 1.0 1 0 0 1 1 1 1 Fungal immunomodulatory protein Fve FAA_hydrolase PF01557.13 KEY70187.1 - 3.2e-49 167.3 0.0 4.9e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KEY70187.1 - 7.1e-27 93.5 0.0 2.1e-26 91.9 0.0 1.8 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Aldo_ket_red PF00248.16 KEY70188.1 - 4.5e-59 199.5 0.0 5.5e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.20 KEY70189.1 - 2.9e-20 72.5 0.0 3.9e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY70189.1 - 6.5e-09 35.2 0.0 2.1e-08 33.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEY70189.1 - 0.015 15.0 0.2 0.78 9.4 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 KEY70190.1 - 3.2e-16 59.2 0.0 4.1e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY70190.1 - 0.00014 21.0 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEY70190.1 - 0.00053 19.7 0.0 0.018 14.7 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KEY70190.1 - 0.024 13.7 0.0 0.33 10.0 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA-synt_1 PF00133.17 KEY70190.1 - 0.12 10.3 0.0 0.16 9.9 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) Kinase-like PF14531.1 KEY70190.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like HET PF06985.6 KEY70192.1 - 5.9e-30 104.2 1.6 1.4e-29 103.0 1.1 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_12 PF13424.1 KEY70194.1 - 3.3e-35 119.8 5.2 8.3e-15 54.5 0.0 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 KEY70194.1 - 2.8e-27 93.7 0.1 6.9e-08 32.1 0.0 4.9 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 KEY70194.1 - 1.1e-10 40.9 3.0 3.6e-06 26.5 0.3 2.7 1 1 1 2 2 2 2 TPR repeat TPR_7 PF13176.1 KEY70194.1 - 3.1e-10 39.0 1.2 0.033 13.9 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEY70194.1 - 4.8e-10 38.5 1.0 0.057 13.3 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEY70194.1 - 2.9e-09 36.1 0.3 0.017 14.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEY70194.1 - 6.2e-06 26.4 1.5 0.18 12.1 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEY70194.1 - 8e-06 25.6 1.0 0.11 12.7 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat NB-ARC PF00931.17 KEY70194.1 - 9.1e-06 24.7 0.1 0.075 11.8 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Apc3 PF12895.2 KEY70194.1 - 1.4e-05 25.1 1.4 0.00074 19.6 0.5 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KEY70194.1 - 0.00013 21.4 0.4 0.5 10.2 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEY70194.1 - 0.00018 21.7 1.4 1.4 9.5 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.7 KEY70194.1 - 0.00024 20.8 3.7 0.69 9.7 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEY70194.1 - 0.00032 21.0 3.9 1.1 10.0 0.1 4.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEY70194.1 - 0.0036 17.9 7.6 0.029 15.0 0.1 3.6 2 1 2 4 4 3 2 Tetratricopeptide repeat AAA_22 PF13401.1 KEY70194.1 - 0.0045 17.1 0.0 0.017 15.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain TPR_4 PF07721.9 KEY70194.1 - 0.026 14.9 0.0 0.026 14.9 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF4066 PF13278.1 KEY70195.1 - 1e-23 83.4 0.0 2.2e-23 82.3 0.0 1.5 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KEY70195.1 - 1e-09 37.9 0.0 1.8e-09 37.1 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DnaG_DnaB_bind PF08278.6 KEY70195.1 - 0.058 13.6 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding GATase_3 PF07685.9 KEY70195.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Glyco_hydro_3 PF00933.16 KEY70196.1 - 1e-78 264.3 0.0 1.5e-78 263.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY70196.1 - 3.5e-35 121.5 0.6 1.1e-34 119.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEY70196.1 - 1.4e-17 63.3 0.1 2.9e-17 62.3 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Zn_clus PF00172.13 KEY70197.1 - 9.7e-09 34.9 6.6 2.6e-08 33.6 4.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY70197.1 - 0.0073 15.2 0.3 0.016 14.1 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_3 PF13302.1 KEY70198.1 - 2.4e-31 108.8 0.0 3e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KEY70198.1 - 2.5e-09 37.2 0.0 4.2e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEY70198.1 - 2.1e-08 34.0 0.1 3.4e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KEY70198.1 - 3.4e-06 26.9 0.0 4.3e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain SchA_CurD PF04486.7 KEY70198.1 - 0.018 14.8 0.1 0.031 14.1 0.1 1.4 1 0 0 1 1 1 0 SchA/CurD like domain Glyoxalase PF00903.20 KEY70199.1 - 2.2e-24 85.8 0.0 2.2e-16 59.9 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KEY70199.1 - 7e-15 54.9 0.0 3.9e-06 26.8 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KEY70199.1 - 2.7e-11 44.0 0.0 5e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 KEY70199.1 - 0.0009 19.1 0.0 1.2 8.9 0.0 3.5 4 0 0 4 4 4 1 Glyoxalase-like domain Glyoxalase_5 PF14696.1 KEY70199.1 - 0.007 16.3 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal FGE-sulfatase PF03781.11 KEY70200.1 - 1.2e-49 169.0 1.4 1.5e-49 168.6 0.9 1.2 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 MFS_1 PF07690.11 KEY70201.1 - 1.9e-34 118.9 24.0 1.9e-34 118.9 16.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY70201.1 - 1.6e-07 30.3 7.4 1.6e-07 30.3 5.1 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter Cu-oxidase_3 PF07732.10 KEY70202.1 - 1.9e-39 134.0 3.5 2.4e-39 133.6 0.9 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KEY70202.1 - 8.9e-35 119.1 11.6 3.8e-27 94.4 0.4 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KEY70202.1 - 1.4e-18 67.3 0.1 2e-11 44.0 0.0 3.3 3 0 0 3 3 3 3 Multicopper oxidase Ferric_reduct PF01794.14 KEY70203.1 - 6.5e-16 58.5 15.6 6.5e-16 58.5 10.8 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KEY70203.1 - 1.2e-07 31.5 0.0 4.2e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 KEY70203.1 - 3.3e-05 23.8 0.4 0.0047 16.8 0.0 2.5 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KEY70203.1 - 0.12 12.9 0.3 0.66 10.5 0.2 2.2 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Amino_oxidase PF01593.19 KEY70204.1 - 6.4e-47 160.6 0.5 2.5e-46 158.6 0.3 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KEY70204.1 - 1e-13 51.0 0.1 9.9e-13 47.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEY70204.1 - 3.4e-11 42.6 0.3 2.2e-10 40.0 0.2 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEY70204.1 - 7.8e-08 31.5 0.5 1.7e-07 30.5 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KEY70204.1 - 4.3e-07 29.2 0.2 7.4e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KEY70204.1 - 5.3e-07 28.4 1.7 6.6e-05 21.5 0.2 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 KEY70204.1 - 1.1e-06 28.8 0.1 0.028 14.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEY70204.1 - 2.2e-05 23.7 0.2 3.9e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEY70204.1 - 4.4e-05 23.4 0.6 0.0017 18.2 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY70204.1 - 5.2e-05 22.3 0.6 0.062 12.1 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_3 PF01494.14 KEY70204.1 - 6e-05 22.2 0.5 0.00011 21.3 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KEY70204.1 - 0.00034 19.6 0.8 0.0073 15.2 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KEY70204.1 - 0.00076 19.8 1.0 0.0022 18.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEY70204.1 - 0.31 10.8 4.5 2.4 7.9 0.1 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Fungal_trans_2 PF11951.3 KEY70205.1 - 6.4e-31 107.3 0.1 8.3e-31 106.9 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Synapsin_N PF10581.4 KEY70205.1 - 0.012 15.4 0.4 0.021 14.6 0.3 1.4 1 0 0 1 1 1 0 Synapsin N-terminal Zn_clus PF00172.13 KEY70208.1 - 4e-09 36.2 12.8 7.3e-09 35.3 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY70208.1 - 0.00045 19.1 0.0 0.00091 18.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3227 PF11537.3 KEY70208.1 - 0.11 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3227) Abhydrolase_4 PF08386.5 KEY70210.1 - 3.6e-17 62.1 0.0 1e-16 60.6 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KEY70210.1 - 9.1e-11 41.7 0.0 1.8e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEY70210.1 - 0.00011 22.2 0.2 0.00032 20.6 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 KEY70211.1 - 5.1e-30 104.3 45.6 8.1e-30 103.7 31.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY70211.1 - 2.5e-07 29.6 14.1 2.5e-07 29.6 9.8 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter CAAD PF14159.1 KEY70211.1 - 0.0022 17.6 0.2 0.021 14.4 0.0 2.7 2 0 0 2 2 2 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase OATP PF03137.15 KEY70211.1 - 0.017 13.2 11.0 0.0089 14.1 3.3 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4385 PF14328.1 KEY70212.1 - 8.7e-56 187.8 2.1 1.1e-55 187.4 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) HET PF06985.6 KEY70213.1 - 1.9e-24 86.4 0.2 1.7e-20 73.6 0.1 2.9 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Peptidase_S8 PF00082.17 KEY70214.1 - 1.1e-42 146.1 0.9 2e-42 145.2 0.6 1.4 1 0 0 1 1 1 1 Subtilase family AAA PF00004.24 KEY70215.1 - 7.4e-17 61.7 0.0 1.4e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEY70215.1 - 0.011 15.7 0.1 0.14 12.1 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 KEY70215.1 - 0.021 14.6 0.0 0.068 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KEY70215.1 - 0.037 14.1 0.0 0.16 12.0 0.0 2.0 1 1 1 2 2 2 0 AAA domain UPF0079 PF02367.12 KEY70215.1 - 0.051 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Aminotran_1_2 PF00155.16 KEY70216.1 - 2.2e-70 237.4 0.0 2.5e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KEY70216.1 - 0.0079 15.3 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Pkinase PF00069.20 KEY70220.1 - 6.3e-69 232.0 0.0 8.6e-69 231.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY70220.1 - 1.7e-37 128.9 0.0 2.4e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY70220.1 - 9.2e-08 31.3 0.0 1.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Lectin_leg-like PF03388.8 KEY70221.1 - 9.5e-61 204.8 0.0 1.3e-60 204.3 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family ATG27 PF09451.5 KEY70221.1 - 0.0022 17.3 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Lectin_legB PF00139.14 KEY70221.1 - 0.0032 16.8 0.1 1.4 8.2 0.0 3.2 3 1 1 4 4 4 2 Legume lectin domain DUF2648 PF10855.3 KEY70221.1 - 0.13 11.7 0.2 0.13 11.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2648) zf-Tim10_DDP PF02953.10 KEY70222.1 - 3.4e-18 64.7 3.8 4.2e-18 64.4 2.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KEY70222.1 - 0.038 13.4 2.1 0.044 13.2 1.4 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF3398 PF11878.3 KEY70222.1 - 0.09 12.6 0.1 0.097 12.5 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3398) DUF2040 PF09745.4 KEY70223.1 - 8.4e-37 125.8 24.8 8.4e-37 125.8 17.2 3.8 2 2 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) DUF3439 PF11921.3 KEY70223.1 - 0.0039 16.9 3.7 0.0088 15.7 2.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) DUF3647 PF12363.3 KEY70223.1 - 0.0041 17.1 4.6 0.013 15.6 3.2 1.8 1 0 0 1 1 1 1 Phage protein UBA_4 PF14555.1 KEY70224.1 - 0.00031 20.2 0.0 0.00049 19.5 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain LysM PF01476.15 KEY70224.1 - 0.0037 17.1 0.0 0.0068 16.2 0.0 1.3 1 0 0 1 1 1 1 LysM domain DZR PF12773.2 KEY70224.1 - 8.2 6.3 13.4 20 5.1 9.3 1.6 1 1 0 1 1 1 0 Double zinc ribbon CPSF_A PF03178.10 KEY70225.1 - 3.1e-99 332.1 0.0 1.8e-98 329.5 0.0 2.2 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 KEY70225.1 - 7.4e-67 225.6 0.0 1.1e-66 225.0 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 KEY70225.1 - 0.0015 18.3 0.5 0.016 15.0 0.4 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat zf-Mss51 PF13824.1 KEY70226.1 - 7.1e-25 86.6 7.9 1.4e-24 85.6 5.5 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KEY70226.1 - 0.011 15.6 1.7 0.011 15.6 1.2 2.1 2 0 0 2 2 2 0 MYND finger YebG PF07130.7 KEY70226.1 - 0.18 11.4 0.1 3.7 7.2 0.0 2.2 2 0 0 2 2 2 0 YebG protein zf-C2H2_4 PF13894.1 KEY70226.1 - 2.5 8.6 6.3 0.98 9.9 1.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PXA PF02194.10 KEY70227.1 - 3.9e-37 127.6 0.0 5.9e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 PXA domain DUF2360 PF10152.4 KEY70227.1 - 0.25 11.6 2.8 0.63 10.3 1.9 1.7 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) zf-C4H2 PF10146.4 KEY70227.1 - 1.8 8.5 4.6 3.3 7.6 3.2 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein HTH_Tnp_Tc5 PF03221.11 KEY70228.1 - 9.5e-10 38.1 0.1 1.6e-08 34.2 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 KEY70228.1 - 3e-07 29.7 0.2 5.3e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.17 KEY70228.1 - 0.00089 18.9 0.2 0.0058 16.3 0.0 2.4 3 0 0 3 3 3 1 MarR family MarR_2 PF12802.2 KEY70228.1 - 0.0039 16.8 0.0 0.012 15.2 0.0 1.8 1 0 0 1 1 1 1 MarR family HTH_23 PF13384.1 KEY70228.1 - 0.02 14.5 0.1 0.072 12.7 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_38 PF13936.1 KEY70228.1 - 0.023 14.2 0.0 0.055 13.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 KEY70228.1 - 0.044 13.0 0.0 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_4 PF13613.1 KEY70228.1 - 0.056 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease DUF2780 PF11075.3 KEY70228.1 - 0.083 12.9 5.2 0.17 11.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function VcgC/VcgE (DUF2780) RPA_C PF08784.6 KEY70228.1 - 0.19 12.1 2.3 5.1 7.5 0.9 3.0 2 0 0 2 2 2 0 Replication protein A C terminal TGS PF02824.16 KEY70229.1 - 1.5e-22 79.1 0.1 3.1e-22 78.1 0.1 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KEY70229.1 - 1.7e-17 63.4 0.0 3.3e-17 62.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEY70229.1 - 2.2e-09 36.7 0.0 1.1e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KEY70229.1 - 6.4e-05 22.8 0.2 0.014 15.2 0.0 2.3 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 KEY70229.1 - 0.0001 21.8 0.2 1.1 8.6 0.0 3.7 2 2 2 4 4 4 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 KEY70229.1 - 0.0088 14.8 0.1 0.018 13.8 0.0 1.4 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 KEY70229.1 - 0.017 15.5 0.0 0.14 12.6 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein DUF211 PF02680.9 KEY70229.1 - 0.068 12.9 0.3 0.19 11.5 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 AIG1 PF04548.11 KEY70229.1 - 0.085 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 AIG1 family CBS PF00571.23 KEY70229.1 - 0.11 12.3 0.1 0.39 10.5 0.1 1.9 2 0 0 2 2 2 0 CBS domain Ank_2 PF12796.2 KEY70230.1 - 1.7e-25 89.1 0.0 2.4e-17 63.0 0.3 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEY70230.1 - 6.6e-21 73.0 1.8 6.1e-08 32.0 0.1 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KEY70230.1 - 9.5e-16 57.4 6.8 2.6e-07 30.6 0.1 4.3 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY70230.1 - 8.9e-15 53.3 0.0 9.1e-06 25.4 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KEY70230.1 - 2e-14 53.6 0.1 2.3e-08 34.3 0.1 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) 2OG-FeII_Oxy_2 PF13532.1 KEY70231.1 - 0.00015 21.6 0.0 0.012 15.4 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Steroid_dh PF02544.11 KEY70232.1 - 3.9e-13 49.4 1.6 3.9e-13 49.4 1.1 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase WSC PF01822.14 KEY70233.1 - 1.7e-36 123.9 28.9 8.5e-21 73.6 5.3 5.5 6 1 0 6 6 6 2 WSC domain PCI PF01399.22 KEY70234.1 - 6.5e-09 36.0 0.6 4.1e-08 33.4 0.0 2.7 2 0 0 2 2 2 1 PCI domain ubiquitin PF00240.18 KEY70235.1 - 8e-08 31.5 0.0 1.3e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 KEY70235.1 - 0.11 13.1 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD G-gamma PF00631.17 KEY70236.1 - 2.2e-24 84.9 0.0 3.1e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 GGL domain Rdx PF10262.4 KEY70237.1 - 9e-28 96.1 0.0 1.1e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Rdx family Metallophos PF00149.23 KEY70238.1 - 1.1e-44 152.2 0.2 1.3e-44 151.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-HC5HC2H_2 PF13832.1 KEY70239.1 - 2.8e-34 117.4 7.2 2.8e-34 117.4 5.0 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KEY70239.1 - 1.2e-26 92.6 6.5 1.2e-26 92.6 4.5 3.2 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 KEY70239.1 - 8.7e-19 68.3 3.8 3.2e-18 66.4 0.0 3.3 3 1 0 3 3 3 1 Enhancer of polycomb-like PHD_2 PF13831.1 KEY70239.1 - 9.5e-15 53.6 2.4 9.5e-15 53.6 1.7 2.2 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 KEY70239.1 - 3.8e-08 32.8 27.0 6.5e-07 28.9 9.0 2.8 2 0 0 2 2 2 2 PHD-finger LRR_4 PF12799.2 KEY70240.1 - 1e-16 60.1 8.1 2.3e-05 23.9 0.7 5.1 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEY70240.1 - 4.3e-13 48.7 5.1 2.1e-08 33.8 1.9 3.3 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KEY70240.1 - 1.3e-09 36.7 8.4 0.65 10.2 0.0 7.1 6 1 1 7 7 7 4 Leucine Rich Repeat LRR_7 PF13504.1 KEY70240.1 - 8.2e-05 22.1 7.1 23 5.7 0.1 7.2 8 0 0 8 8 8 2 Leucine rich repeat LRR_6 PF13516.1 KEY70240.1 - 0.0023 17.8 3.8 32 5.0 0.0 5.5 6 0 0 6 6 6 0 Leucine Rich repeat RAP1 PF07218.6 KEY70240.1 - 2.2 6.2 6.0 4.2 5.3 4.2 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Biotin_lipoyl PF00364.17 KEY70242.1 - 3e-17 62.0 2.4 5.5e-17 61.1 1.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KEY70242.1 - 6.7e-08 32.0 0.2 2.9e-07 30.0 0.1 2.2 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KEY70242.1 - 1.8e-05 24.3 0.3 0.00049 19.7 0.0 3.0 2 1 1 3 3 3 1 Biotin-lipoyl like QRPTase_N PF02749.11 KEY70242.1 - 0.13 12.1 0.0 0.33 10.8 0.0 1.7 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain CoA_transf_3 PF02515.12 KEY70243.1 - 2.9e-23 82.1 0.0 6.3e-23 81.0 0.0 1.5 2 0 0 2 2 2 1 CoA-transferase family III Fungal_trans PF04082.13 KEY70244.1 - 8.2e-20 70.7 0.0 1.5e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY70244.1 - 4.4e-08 32.8 12.1 9.7e-08 31.8 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_16 PF13432.1 KEY70244.1 - 0.029 15.0 0.3 0.072 13.7 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Dioxygenase_C PF00775.16 KEY70245.1 - 1.9e-53 180.4 0.0 2.6e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KEY70245.1 - 2.2e-14 53.1 0.0 4.2e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KEY70245.1 - 0.0015 18.5 0.0 0.031 14.3 0.0 2.6 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain OPT PF03169.10 KEY70246.1 - 1.6e-165 552.1 46.8 2.8e-100 336.5 14.0 2.0 2 0 0 2 2 2 2 OPT oligopeptide transporter protein DUF2207 PF09972.4 KEY70246.1 - 2.2 6.7 4.2 1 7.8 0.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) ketoacyl-synt PF00109.21 KEY70247.1 - 1.3e-59 201.7 8.5 2.6e-59 200.7 1.8 2.3 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KEY70247.1 - 1.6e-35 121.5 2.3 4.6e-35 120.0 1.6 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Ubiq_cyt_C_chap PF03981.7 KEY70247.1 - 4.3e-35 120.6 0.1 9e-35 119.5 0.1 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Thiolase_N PF00108.18 KEY70247.1 - 0.00011 21.2 0.3 0.0013 17.7 0.1 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KEY70247.1 - 0.038 13.4 4.2 0.047 13.1 0.2 2.9 2 1 1 3 3 3 0 Thiolase, C-terminal domain DHFR_1 PF00186.14 KEY70248.1 - 1.6e-33 115.5 0.0 3.4e-33 114.5 0.0 1.6 1 1 0 1 1 1 1 Dihydrofolate reductase DSBA PF01323.15 KEY70248.1 - 1e-15 57.7 0.0 2.4e-15 56.6 0.0 1.6 1 1 0 1 1 1 1 DSBA-like thioredoxin domain adh_short PF00106.20 KEY70249.1 - 2.3e-22 79.7 0.1 3.6e-22 79.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY70249.1 - 9.1e-08 32.1 0.0 1.2e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY70249.1 - 2.1e-07 30.8 0.0 3.2e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 KEY70249.1 - 0.099 11.7 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 KEY70249.1 - 0.11 12.2 0.2 0.37 10.6 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AAA PF00004.24 KEY70250.1 - 2e-49 167.1 0.0 3.4e-42 143.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEY70250.1 - 2e-07 31.2 0.1 7.6e-05 22.7 0.1 3.2 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 KEY70250.1 - 1.5e-06 27.7 0.0 4.1e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 KEY70250.1 - 2.1e-05 24.5 0.0 5.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KEY70250.1 - 3.2e-05 24.0 0.5 0.0021 18.1 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 KEY70250.1 - 0.00023 21.0 0.2 0.011 15.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KEY70250.1 - 0.0011 18.9 0.0 0.04 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KEY70250.1 - 0.0011 18.6 0.0 0.0079 15.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KEY70250.1 - 0.0016 18.6 0.0 0.025 14.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_17 PF13207.1 KEY70250.1 - 0.0024 18.6 0.0 0.025 15.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEY70250.1 - 0.0049 17.1 0.3 0.05 13.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEY70250.1 - 0.0052 16.4 0.7 0.028 14.1 0.1 2.6 3 0 0 3 3 2 1 Part of AAA domain TIP49 PF06068.8 KEY70250.1 - 0.0088 14.7 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_28 PF13521.1 KEY70250.1 - 0.01 15.8 0.0 0.094 12.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KEY70250.1 - 0.013 14.5 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 KEY70250.1 - 0.02 14.9 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 KEY70250.1 - 0.034 13.5 0.0 0.12 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KEY70250.1 - 0.044 13.4 0.0 0.21 11.2 0.1 2.1 2 1 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 KEY70250.1 - 0.05 12.7 0.1 0.13 11.4 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.12 KEY70250.1 - 0.073 11.9 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 KEY70250.1 - 0.16 11.6 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 KEY70250.1 - 0.58 10.0 0.3 1.4 8.7 0.0 1.7 2 0 0 2 2 1 0 Torsin tRNA-synt_1e PF01406.14 KEY70251.1 - 3.3e-24 85.5 0.0 5.7e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain HYLS1_C PF15311.1 KEY70251.1 - 0.04 14.1 4.1 0.13 12.4 0.1 3.1 2 1 0 2 2 2 0 Hydrolethalus syndrome protein 1 C-terminus Carb_anhydrase PF00194.16 KEY70252.1 - 6.2e-22 77.8 0.1 1.7e-21 76.3 0.1 1.7 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Dus PF01207.12 KEY70254.1 - 2.6e-60 203.8 0.0 7.1e-60 202.4 0.0 1.7 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 KEY70254.1 - 0.04 12.8 0.0 0.1 11.5 0.0 1.6 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase GCK PF07802.6 KEY70254.1 - 0.091 12.8 0.0 0.32 11.1 0.0 1.9 1 0 0 1 1 1 0 GCK domain Ifi-6-16 PF06140.8 KEY70255.1 - 0.0032 17.2 31.3 0.0064 16.2 21.6 1.6 1 1 0 1 1 1 1 Interferon-induced 6-16 family MIF4G PF02854.14 KEY70256.1 - 9.7e-27 93.7 0.6 2e-26 92.6 0.2 1.7 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 KEY70256.1 - 6e-22 77.4 0.0 2.5e-21 75.5 0.0 2.1 2 0 0 2 2 2 1 MA3 domain FAM176 PF14851.1 KEY70256.1 - 0.14 11.8 3.9 0.37 10.4 2.7 1.7 1 0 0 1 1 1 0 FAM176 family DUF1777 PF08648.7 KEY70256.1 - 2 8.1 22.7 0.14 11.8 4.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1777) CDC45 PF02724.9 KEY70256.1 - 2.1 6.3 11.5 0.99 7.3 3.5 2.3 2 0 0 2 2 2 0 CDC45-like protein Corona_nucleoca PF00937.13 KEY70256.1 - 4.4 6.1 15.3 0.17 10.8 6.5 1.6 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein NOA36 PF06524.7 KEY70256.1 - 5.5 6.1 7.8 9.2 5.4 5.4 1.3 1 0 0 1 1 1 0 NOA36 protein DUF1509 PF07420.6 KEY70256.1 - 9.5 5.3 23.5 0.12 11.6 8.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1509) DPM2 PF07297.7 KEY70257.1 - 4.1e-32 110.2 1.8 4.8e-32 110.0 1.2 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 KEY70257.1 - 0.00017 21.1 1.3 0.00019 21.0 0.9 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 KEY70257.1 - 0.0022 17.8 0.2 0.0022 17.8 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) DUF4083 PF13314.1 KEY70257.1 - 0.0088 15.8 0.2 0.016 15.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4083) DUF1049 PF06305.6 KEY70257.1 - 0.19 11.2 0.1 0.19 11.2 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) TPPK_C PF12555.3 KEY70257.1 - 2.3 7.9 4.6 1 9.1 0.6 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal PHD PF00628.24 KEY70260.1 - 1.3e-09 37.6 7.1 2.1e-09 36.9 4.9 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 KEY70260.1 - 0.0022 18.2 0.0 0.0069 16.6 0.0 1.9 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.1 KEY70260.1 - 0.25 11.4 1.1 0.51 10.5 0.8 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.1 KEY70260.1 - 0.35 10.2 1.6 0.57 9.5 1.1 1.3 1 0 0 1 1 1 0 PHD-finger Bactofilin PF04519.8 KEY70261.1 - 8.3e-09 35.3 0.4 0.00036 20.5 0.0 2.7 1 1 2 3 3 3 3 Polymer-forming cytoskeletal DUF342 PF03961.8 KEY70261.1 - 1.4e-05 23.7 0.1 3.7e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF342) MinC_C PF03775.11 KEY70261.1 - 4.7e-05 22.9 1.2 0.086 12.4 0.0 3.1 1 1 2 3 3 3 2 Septum formation inhibitor MinC, C-terminal domain DUF748 PF05359.6 KEY70261.1 - 0.0044 17.0 0.0 14 5.6 0.0 3.1 1 1 2 3 3 3 3 Domain of Unknown Function (DUF748) Fun_ATP-synt_8 PF05933.8 KEY70262.1 - 6.4 6.8 7.7 16 5.6 2.8 2.6 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) ARS2 PF04959.8 KEY70263.1 - 0.0022 18.2 0.5 0.0056 16.8 0.3 1.7 1 0 0 1 1 1 1 Arsenite-resistance protein 2 zf-BED PF02892.10 KEY70263.1 - 0.013 15.2 2.4 0.025 14.3 1.7 1.4 1 0 0 1 1 1 0 BED zinc finger zf-C2H2 PF00096.21 KEY70263.1 - 0.013 15.7 3.1 0.039 14.3 2.2 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY70263.1 - 0.026 14.8 2.6 0.069 13.5 1.8 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger DUF3602 PF12223.3 KEY70264.1 - 4.1e-10 39.9 12.7 2e-07 31.2 3.4 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) DnaJ PF00226.26 KEY70265.1 - 4.7e-07 29.4 0.0 6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 KEY70265.1 - 6.9e-07 29.1 0.0 7.9e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Pam16 DNA_pol_A_exo1 PF01612.15 KEY70266.1 - 0.12 11.8 0.0 0.33 10.4 0.0 1.7 1 1 1 2 2 2 0 3'-5' exonuclease Ku_N PF03731.10 KEY70267.1 - 8.4e-26 90.7 0.4 1.4e-25 90.0 0.3 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 KEY70267.1 - 3.2e-24 85.4 0.0 5.5e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 KEY70267.1 - 3.6e-16 59.1 0.0 8.4e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like DUF4149 PF13664.1 KEY70268.1 - 1.5e-22 79.5 3.8 1.5e-22 79.5 2.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) CD99L2 PF12301.3 KEY70268.1 - 0.19 11.4 0.0 0.27 10.9 0.0 1.1 1 0 0 1 1 1 0 CD99 antigen like protein 2 DUF2570 PF10828.3 KEY70269.1 - 0.02 14.5 1.5 0.028 14.0 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Hydrolase_6 PF13344.1 KEY70270.1 - 9.2e-25 86.4 0.0 1.4e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEY70270.1 - 8.8e-11 41.3 0.0 2.3e-10 40.0 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 KEY70270.1 - 3.7e-10 40.5 0.0 8.8e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KEY70270.1 - 1e-05 25.8 0.0 0.0012 19.1 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DUF3893 PF13032.1 KEY70270.1 - 0.059 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3893) Glyco_tranf_2_4 PF13704.1 KEY70270.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF1295 PF06966.7 KEY70271.1 - 2.5e-29 102.2 19.2 2.6e-26 92.3 13.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 KEY70271.1 - 0.097 12.8 1.0 0.55 10.4 0.0 2.6 2 1 1 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Topoisom_bac PF01131.15 KEY70272.1 - 2.3e-91 306.6 0.0 6.2e-87 292.0 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 KEY70272.1 - 3.5e-19 68.6 0.0 7.1e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Stb3 PF10330.4 KEY70273.1 - 1.4e-35 120.8 0.0 2.3e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein zf-C2H2 PF00096.21 KEY70274.1 - 1.9e-07 31.0 19.6 9.8e-06 25.6 2.6 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KEY70274.1 - 7.7e-05 22.7 4.4 7.7e-05 22.7 3.0 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KEY70274.1 - 0.00044 20.3 1.1 0.00044 20.3 0.8 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KEY70274.1 - 0.001 19.1 1.0 0.001 19.1 0.7 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEY70274.1 - 0.0021 18.1 3.5 0.14 12.3 0.6 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-TRAF PF02176.13 KEY70274.1 - 0.35 11.2 7.5 0.091 13.1 2.2 2.1 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_6 PF13912.1 KEY70274.1 - 0.75 9.7 3.4 3.2 7.8 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KEY70274.1 - 1.4 9.0 7.7 4.6 7.3 4.2 2.6 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) ARS2 PF04959.8 KEY70274.1 - 7.1 6.7 11.0 1.3 9.1 2.7 3.1 3 0 0 3 3 3 0 Arsenite-resistance protein 2 DUF2215 PF10225.4 KEY70274.1 - 9.9 5.5 5.3 18 4.6 3.7 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Dicistro_VP4 PF11492.3 KEY70275.1 - 0.11 12.5 11.2 35 4.5 0.0 7.9 9 0 0 9 9 9 0 Cricket paralysis virus, VP4 RIC1 PF07064.8 KEY70275.1 - 3.9 6.8 0.0 3.5e+02 0.4 0.0 3.9 2 0 0 2 2 2 0 RIC1 Fungal_trans PF04082.13 KEY70276.1 - 9.6e-09 34.4 0.1 1.5e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY70276.1 - 1.4e-07 31.2 11.0 1.4e-07 31.2 7.6 3.4 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain PUF PF00806.14 KEY70278.1 - 1.4e-52 172.3 6.3 1.1e-07 30.9 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF1400 PF07176.6 KEY70278.1 - 0.073 12.9 0.8 0.48 10.3 0.1 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) MgtE_N PF03448.12 KEY70278.1 - 0.14 12.5 2.1 3.8 7.8 0.0 3.6 2 2 0 2 2 2 0 MgtE intracellular N domain DUF2299 PF10061.4 KEY70278.1 - 0.36 10.2 2.0 33 3.9 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2299) DUF1640 PF07798.6 KEY70279.1 - 1.7e-12 47.7 3.2 2.2e-12 47.3 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF1191 PF06697.7 KEY70279.1 - 0.0063 15.3 0.3 0.01 14.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Phage_connect_1 PF05135.8 KEY70279.1 - 0.01 16.0 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 1 Phage gp6-like head-tail connector protein Uds1 PF15456.1 KEY70280.1 - 4.3e-35 120.3 5.5 7.9e-35 119.5 3.8 1.4 1 0 0 1 1 1 1 Up-regulated During Septation TBPIP PF07106.8 KEY70280.1 - 0.22 11.0 1.1 1 8.8 0.7 1.9 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PXA PF02194.10 KEY70281.1 - 3.7e-35 121.1 0.2 1.1e-34 119.6 0.1 1.8 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 KEY70281.1 - 3.7e-18 65.6 0.0 1e-17 64.1 0.0 1.8 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 KEY70281.1 - 5.9e-08 32.5 0.2 1.9e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 PX domain PC4 PF02229.11 KEY70282.1 - 1.1e-22 79.0 0.1 1.9e-22 78.2 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) YqfQ PF14181.1 KEY70282.1 - 0.069 13.1 2.1 0.11 12.5 0.1 1.9 2 0 0 2 2 2 0 YqfQ-like protein MFS_1 PF07690.11 KEY70283.1 - 7.8e-32 110.3 51.2 6.7e-28 97.4 22.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY70283.1 - 8.7e-20 70.7 25.0 4e-19 68.5 17.0 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1228 PF06779.9 KEY70283.1 - 0.04 13.9 7.2 0.24 11.4 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) MFS_2 PF13347.1 KEY70283.1 - 1.2 7.5 22.5 0.067 11.5 0.7 3.5 3 1 1 4 4 4 0 MFS/sugar transport protein DnaJ PF00226.26 KEY70284.1 - 2.1e-12 46.5 0.0 3.8e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Cytochrom_B561 PF03188.11 KEY70285.1 - 2.8e-08 33.6 15.3 2.8e-08 33.6 10.6 1.9 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 KEY70285.1 - 1.8e-05 24.2 10.0 1.8e-05 24.2 6.9 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF2427) DUF2306 PF10067.4 KEY70285.1 - 0.022 14.8 2.1 0.022 14.8 1.4 2.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2306) RCR PF12273.3 KEY70285.1 - 0.037 14.5 0.2 0.037 14.5 0.1 2.5 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red DUF973 PF06157.6 KEY70285.1 - 0.12 11.3 7.5 0.17 10.8 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) SdpI PF13630.1 KEY70285.1 - 1.3 8.8 21.3 0.3 10.8 1.7 3.4 3 1 0 3 3 3 0 SdpI/YhfL protein family Cation_efflux PF01545.16 KEY70285.1 - 1.9 7.4 11.9 3.2 6.7 8.2 1.2 1 0 0 1 1 1 0 Cation efflux family MFS_1 PF07690.11 KEY70286.1 - 9.5e-26 90.3 35.6 1.4e-25 89.7 15.2 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY70286.1 - 1.8e-06 26.8 0.6 1.8e-06 26.8 0.4 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 KEY70286.1 - 0.0088 14.2 11.0 0.012 13.7 1.3 2.6 2 1 0 2 2 2 2 Transmembrane secretion effector Cation_ATPase_C PF00689.16 KEY70286.1 - 0.21 11.0 8.9 3.2 7.2 0.7 2.8 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Ureidogly_hydro PF04115.7 KEY70287.1 - 2.6e-46 156.9 0.0 3e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase 2_5_RNA_ligase2 PF13563.1 KEY70288.1 - 0.012 15.3 0.0 0.2 11.3 0.0 2.2 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 KEY70288.1 - 0.04 13.8 0.1 5.7 6.9 0.0 2.6 2 0 0 2 2 2 0 LigT like Phosphoesterase Ribosomal_L44 PF00935.14 KEY70289.1 - 2.8e-34 116.9 12.5 4.1e-34 116.4 8.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Coatomer_E PF04733.9 KEY70290.1 - 7.1e-63 212.4 2.5 8.2e-63 212.2 1.7 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 KEY70290.1 - 2.3e-08 34.2 13.2 0.001 19.3 0.7 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KEY70290.1 - 2.9e-06 27.3 0.5 0.19 11.9 0.0 3.5 2 2 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KEY70290.1 - 4.7e-06 26.7 12.3 0.0083 16.6 0.8 5.8 4 3 2 7 7 7 1 Tetratricopeptide repeat Type_III_YscG PF09477.5 KEY70290.1 - 2.4e-05 24.3 4.8 0.0074 16.3 0.0 3.7 1 1 1 3 3 3 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_11 PF13414.1 KEY70290.1 - 8.4e-05 22.1 1.2 0.0062 16.1 0.0 3.5 2 1 1 3 3 3 1 TPR repeat TPR_8 PF13181.1 KEY70290.1 - 0.00012 21.6 0.1 0.044 13.5 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEY70290.1 - 0.00018 20.9 0.0 0.11 12.1 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEY70290.1 - 0.00048 19.8 8.2 0.0076 16.0 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEY70290.1 - 0.00058 20.4 10.3 0.078 13.6 0.6 4.3 3 2 3 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEY70290.1 - 0.00078 19.3 4.1 0.11 12.4 0.2 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_5 PF12688.2 KEY70290.1 - 0.0009 19.2 3.2 0.25 11.3 0.1 2.7 2 1 0 2 2 2 2 Tetratrico peptide repeat TPR_10 PF13374.1 KEY70290.1 - 0.041 13.8 1.8 32 4.6 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 KEY70290.1 - 0.079 12.8 4.1 0.61 9.9 0.2 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEY70290.1 - 0.084 13.3 0.7 9.2 6.9 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat ATP-synt_DE PF00401.15 KEY70290.1 - 1.1 9.1 6.0 16 5.5 0.0 2.8 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain TPR_4 PF07721.9 KEY70290.1 - 1.8 9.1 14.5 3.1 8.5 0.2 5.3 7 0 0 7 7 4 0 Tetratricopeptide repeat BTAD PF03704.12 KEY70290.1 - 2.5 8.4 9.9 2.1 8.6 2.1 3.0 1 1 1 3 3 3 0 Bacterial transcriptional activator domain MBF1 PF08523.5 KEY70292.1 - 2e-22 78.9 0.7 4e-22 77.9 0.5 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 KEY70292.1 - 6.2e-12 45.1 0.0 1e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 KEY70292.1 - 6.2e-05 22.9 0.0 9.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 KEY70292.1 - 7e-05 22.9 0.0 0.00015 21.8 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain MRP-L27 PF09809.4 KEY70292.1 - 0.011 15.3 0.3 0.016 14.7 0.2 1.5 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L27 HTH_24 PF13412.1 KEY70292.1 - 0.083 12.2 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding GFA PF04828.9 KEY70293.1 - 4.7e-23 80.9 0.0 7e-23 80.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KEY70293.1 - 0.06 12.5 0.2 0.25 10.6 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.1 KEY70293.1 - 0.12 12.0 0.1 0.12 12.0 0.0 2.5 3 0 0 3 3 3 0 Nudix N-terminal zinc_ribbon_2 PF13240.1 KEY70293.1 - 0.17 11.4 1.3 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 KEY70293.1 - 0.36 10.6 2.8 0.82 9.5 0.9 2.3 2 1 0 2 2 2 0 Double zinc ribbon Sporozoite_P67 PF05642.6 KEY70294.1 - 0.00035 18.6 4.7 0.00038 18.4 3.3 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DUF4637 PF15470.1 KEY70294.1 - 1 8.9 5.1 2 8.0 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF4397 PF14344.1 KEY70295.1 - 0.35 11.2 4.8 0.73 10.1 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4397) SpoU_methylase PF00588.14 KEY70296.1 - 9.3e-24 83.9 0.0 1.5e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 KEY70296.1 - 4.9e-12 45.8 0.0 8.2e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding zf-PHD-like PF15446.1 KEY70297.1 - 9.5e-68 226.8 12.1 1.8e-67 226.0 8.4 1.4 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 KEY70297.1 - 1.6e-54 184.7 0.0 2.4e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEY70297.1 - 2.8e-14 52.7 0.0 7.8e-14 51.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 KEY70297.1 - 4e-09 36.0 2.3 3.3e-05 23.4 0.7 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 KEY70297.1 - 2e-06 27.4 16.2 1e-05 25.0 3.3 3.1 2 1 1 3 3 3 2 PHD-finger PHD_2 PF13831.1 KEY70297.1 - 8.1e-05 21.8 0.7 8.1e-05 21.8 0.5 2.9 4 0 0 4 4 4 1 PHD-finger Prok-RING_1 PF14446.1 KEY70297.1 - 0.0024 17.5 2.5 0.0024 17.5 1.7 3.2 3 1 0 3 3 3 1 Prokaryotic RING finger family 1 SUR7 PF06687.7 KEY70299.1 - 2.8e-38 131.6 12.6 5.6e-37 127.3 5.5 1.5 1 1 1 2 2 2 2 SUR7/PalI family DUF3433 PF11915.3 KEY70302.1 - 1.2e-42 143.9 22.7 1.1e-26 92.7 1.4 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) TRP PF06011.7 KEY70303.1 - 1.8e-146 488.1 37.0 2.3e-146 487.8 25.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KEY70303.1 - 4.7e-38 130.4 0.2 7.2e-38 129.8 0.1 1.3 1 0 0 1 1 1 1 ML-like domain AIM24 PF01987.12 KEY70306.1 - 2.3e-51 174.3 0.6 2.8e-51 174.0 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 zf-C2H2_4 PF13894.1 KEY70308.1 - 6.9e-07 29.1 16.3 0.026 14.8 0.6 4.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY70308.1 - 0.00042 20.4 11.3 0.03 14.6 0.8 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type PcfK PF14058.1 KEY70308.1 - 0.057 13.5 0.2 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 PcfK-like protein zf-C2H2_jaz PF12171.3 KEY70308.1 - 0.071 13.2 3.9 6.4 7.0 0.8 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KEY70308.1 - 0.15 12.3 5.8 1.7 9.0 1.4 3.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 KEY70310.1 - 1.7e-07 31.0 48.5 0.0051 17.0 0.5 7.6 6 1 1 7 7 7 5 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY70310.1 - 8.3e-06 25.8 42.6 0.0095 16.2 0.7 6.9 5 1 1 6 6 6 5 Zinc finger, C2H2 type THP2 PF09432.5 KEY70310.1 - 0.2 11.4 0.0 0.57 10.0 0.0 1.7 1 0 0 1 1 1 0 Tho complex subunit THP2 zf-met PF12874.2 KEY70310.1 - 0.79 10.0 13.3 3.3 8.0 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KEY70310.1 - 4.2 7.6 19.6 0.92 9.7 0.2 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Cyt-b5 PF00173.23 KEY70311.1 - 2.2e-17 62.6 0.0 2.6e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TPR_12 PF13424.1 KEY70312.1 - 2.9e-08 33.5 0.0 0.039 13.8 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEY70312.1 - 7.5e-08 31.6 0.0 0.025 14.2 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEY70312.1 - 1.3e-07 31.1 0.0 0.084 12.5 0.0 4.0 4 1 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 KEY70312.1 - 3.7e-07 29.5 0.2 0.0069 16.2 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEY70312.1 - 7.6e-05 22.2 0.1 8.5 6.4 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat FANCI_S1 PF14675.1 KEY70312.1 - 0.14 11.5 0.2 0.3 10.4 0.0 1.6 2 0 0 2 2 2 0 FANCI solenoid 1 bZIP_1 PF00170.16 KEY70313.1 - 1.2e-08 34.7 6.4 2.2e-08 33.9 4.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 KEY70313.1 - 0.095 12.2 0.9 0.18 11.3 0.6 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain bZIP_Maf PF03131.12 KEY70313.1 - 0.096 12.9 12.2 0.21 11.8 8.5 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor Rad52_Rad22 PF04098.10 KEY70314.1 - 3.3e-58 195.7 0.0 5.3e-58 195.1 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Cut8_C PF08559.5 KEY70314.1 - 2e-45 154.1 0.0 3.3e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 KEY70314.1 - 6.3e-16 57.8 0.4 1.5e-15 56.7 0.3 1.7 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 KEY70314.1 - 6.1e-08 32.5 2.3 1.8e-07 31.0 1.6 1.9 1 0 0 1 1 1 1 Cut8 proteasome-binding domain RRM_6 PF14259.1 KEY70315.1 - 1.8e-17 63.0 0.0 6.1e-08 32.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEY70315.1 - 7e-17 60.8 0.2 1.1e-09 37.7 0.0 3.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY70315.1 - 0.03 14.1 0.1 6.5 6.6 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEY70315.1 - 0.11 12.2 0.0 0.39 10.5 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KEY70315.1 - 0.17 11.7 5.5 0.14 12.0 0.3 2.8 3 0 0 3 3 3 0 RNA binding motif DSBA PF01323.15 KEY70316.1 - 4.5e-11 42.6 1.0 5.4e-11 42.4 0.7 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain zf-CCHC PF00098.18 KEY70318.1 - 2.2e-06 27.3 28.8 0.16 11.9 1.2 5.5 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.1 KEY70318.1 - 0.0039 16.8 24.5 0.67 9.6 0.1 5.3 3 1 2 5 5 5 4 Zinc knuckle ORMDL PF04061.9 KEY70319.1 - 5.1e-60 200.9 4.6 6.2e-60 200.6 3.2 1.1 1 0 0 1 1 1 1 ORMDL family COesterase PF00135.23 KEY70321.1 - 2.1e-95 320.4 0.0 3e-95 319.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEY70321.1 - 5.8e-06 26.0 0.6 3.3e-05 23.5 0.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_M1 PF01433.15 KEY70322.1 - 4e-134 447.5 1.6 5.3e-134 447.1 1.1 1.1 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KEY70322.1 - 6.5e-68 229.3 0.0 1.1e-67 228.6 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KEY70322.1 - 2.8e-21 75.8 3.4 4.4e-21 75.2 0.2 2.4 1 1 1 2 2 2 1 Peptidase MA superfamily DUF45 PF01863.12 KEY70322.1 - 0.029 14.1 0.4 0.13 11.9 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function DUF45 DUF2808 PF10989.3 KEY70322.1 - 0.062 12.9 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) Tcp11 PF05794.8 KEY70324.1 - 2e-45 155.3 0.1 2e-45 155.3 0.1 1.6 2 0 0 2 2 2 1 T-complex protein 11 Y_phosphatase PF00102.22 KEY70325.1 - 3.4e-61 206.5 0.0 7.3e-53 179.3 0.0 3.3 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.15 KEY70325.1 - 2.1e-14 53.8 0.0 4.9e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 KEY70325.1 - 0.026 14.7 0.0 0.083 13.1 0.0 1.9 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 KEY70325.1 - 0.11 12.0 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF1989 PF09347.5 KEY70326.1 - 4.9e-52 175.7 0.0 6e-52 175.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) AAA PF00004.24 KEY70327.1 - 9.2e-44 148.8 0.0 1.5e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEY70327.1 - 5e-08 32.7 0.0 1.2e-07 31.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KEY70327.1 - 2.4e-07 30.8 0.0 4.5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KEY70327.1 - 2.1e-06 27.8 0.0 6.4e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEY70327.1 - 9.1e-06 25.8 0.1 0.00051 20.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEY70327.1 - 0.00011 21.8 0.1 0.00024 20.7 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 KEY70327.1 - 0.00013 21.1 0.0 0.00024 20.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KEY70327.1 - 0.00013 21.4 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 KEY70327.1 - 0.0003 21.5 0.0 0.00073 20.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 KEY70327.1 - 0.0015 17.3 0.0 0.0027 16.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 KEY70327.1 - 0.0016 18.3 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KEY70327.1 - 0.0019 18.0 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEY70327.1 - 0.0021 17.1 0.0 0.0039 16.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 KEY70327.1 - 0.0033 16.8 0.1 0.016 14.6 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 KEY70327.1 - 0.0048 16.8 0.0 0.0086 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KEY70327.1 - 0.0054 15.8 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_18 PF13238.1 KEY70327.1 - 0.006 16.8 0.0 0.028 14.7 0.0 2.2 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.16 KEY70327.1 - 0.0061 15.7 0.1 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KEY70327.1 - 0.0063 16.1 0.0 0.02 14.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KEY70327.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.11 KEY70327.1 - 0.015 14.5 0.0 0.049 12.8 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 KEY70327.1 - 0.017 14.6 0.1 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2072 PF09845.4 KEY70327.1 - 0.02 14.8 0.2 0.043 13.7 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Sigma54_activat PF00158.21 KEY70327.1 - 0.021 14.2 0.0 0.094 12.1 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 KEY70327.1 - 0.023 14.8 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Histone PF00125.19 KEY70327.1 - 0.047 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Sigma54_activ_2 PF14532.1 KEY70327.1 - 0.048 13.7 0.0 0.11 12.5 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 KEY70327.1 - 0.053 13.1 0.0 0.27 10.8 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 KEY70327.1 - 0.067 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KEY70327.1 - 0.078 11.8 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.10 KEY70327.1 - 0.18 11.4 1.1 1.1 8.9 0.0 2.6 3 1 1 4 4 4 0 NTPase Na_Ca_ex PF01699.19 KEY70328.1 - 6.4e-31 106.8 24.1 6.9e-19 67.8 6.6 3.7 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 KEY70328.1 - 2.2e-14 53.5 9.5 2.2e-14 53.5 6.6 3.5 2 0 0 2 2 2 1 Domain of unknown function (DUF307) MFS_1 PF07690.11 KEY70329.1 - 5.4e-16 58.2 35.3 5.4e-16 58.2 24.5 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily Clathrin PF00637.15 KEY70330.1 - 1.5e-23 82.9 2.8 1.7e-21 76.3 0.3 2.7 3 0 0 3 3 3 2 Region in Clathrin and VPS PNP_UDP_1 PF01048.15 KEY70330.1 - 0.0045 15.9 0.0 0.19 10.7 0.0 2.5 2 0 0 2 2 2 1 Phosphorylase superfamily CTP_transf_2 PF01467.21 KEY70330.1 - 0.0049 16.9 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase TPR_11 PF13414.1 KEY70330.1 - 0.066 12.8 0.1 0.4 10.3 0.0 2.4 2 0 0 2 2 2 0 TPR repeat SPOB_a PF14689.1 KEY70330.1 - 0.55 9.8 5.5 0.57 9.7 0.1 2.9 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain p450 PF00067.17 KEY70331.1 - 1.7e-56 191.7 0.0 2.3e-56 191.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 KEY70332.1 - 0.00012 21.8 0.0 0.00025 20.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY70332.1 - 0.037 14.5 0.0 0.3 11.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain HATPase_c_3 PF13589.1 KEY70335.1 - 1.3e-15 57.2 0.0 2.8e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 KEY70335.1 - 1.2e-06 28.1 0.1 3.1e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 KEY70335.1 - 0.014 15.0 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LINES_C PF14695.1 KEY70335.1 - 0.045 13.0 0.1 0.096 11.9 0.1 1.5 1 0 0 1 1 1 0 Lines C-terminus Striatin PF08232.7 KEY70336.1 - 2.2e-34 118.6 2.5 3.6e-34 117.9 1.7 1.4 1 0 0 1 1 1 1 Striatin family WD40 PF00400.27 KEY70336.1 - 1.1e-29 101.1 22.2 2e-07 30.6 0.1 7.3 7 1 0 7 7 7 5 WD domain, G-beta repeat Alg14 PF08660.6 KEY70337.1 - 1.2e-37 129.5 0.0 1.8e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like RskA PF10099.4 KEY70337.1 - 0.071 12.8 0.0 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA O-antigen_lig PF13425.1 KEY70337.1 - 0.075 13.0 0.9 0.52 10.2 0.0 2.1 2 0 0 2 2 2 0 O-antigen ligase like membrane protein MRP-S25 PF13741.1 KEY70338.1 - 1.9e-68 230.3 12.2 8.6e-63 211.8 5.1 2.0 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 KEY70338.1 - 0.0045 16.8 0.4 0.017 15.0 0.3 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 PPR_2 PF13041.1 KEY70339.1 - 3.2e-15 55.8 1.4 7.3e-06 25.8 0.0 5.2 4 2 1 5 5 5 3 PPR repeat family PPR_3 PF13812.1 KEY70339.1 - 2.6e-14 52.2 1.5 0.00023 21.2 0.0 5.5 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.15 KEY70339.1 - 4.5e-13 48.2 3.6 1.9e-05 24.2 0.0 4.6 4 0 0 4 4 4 2 PPR repeat PPR_1 PF12854.2 KEY70339.1 - 0.001 18.4 5.8 0.24 10.8 0.0 3.6 4 0 0 4 4 4 2 PPR repeat COX7C PF02935.11 KEY70340.1 - 1.8e-13 50.0 1.6 2.1e-13 49.8 1.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.1 KEY70341.1 - 1.8e-88 296.1 0.0 3.3e-88 295.3 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 KEY70341.1 - 4.3e-59 198.7 2.9 8.2e-59 197.8 2.0 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KEY70341.1 - 1.4e-21 76.6 0.0 4.1e-21 75.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY70341.1 - 1.7e-07 30.9 0.0 4.5e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEY70341.1 - 0.0015 18.3 1.7 0.29 10.9 0.0 3.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 KEY70341.1 - 0.0067 15.3 0.0 0.015 14.1 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2407 PF10302.4 KEY70342.1 - 1.6e-23 82.7 0.0 3.5e-23 81.6 0.0 1.6 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain DUF2407_C PF13373.1 KEY70342.1 - 2.7e-23 82.4 0.1 3.7e-23 81.9 0.1 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain Ima1_N PF09779.4 KEY70343.1 - 2.3e-38 131.6 5.3 3.5e-38 131.0 3.7 1.3 1 0 0 1 1 1 1 Ima1 N-terminal domain Casein_kappa PF00997.13 KEY70343.1 - 0.025 14.3 0.5 0.054 13.1 0.3 1.5 1 0 0 1 1 1 0 Kappa casein DZR PF12773.2 KEY70343.1 - 0.11 12.3 3.2 1.6 8.5 0.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon Y_phosphatase2 PF03162.8 KEY70344.1 - 3.5e-44 150.0 0.0 7.3e-44 149.0 0.0 1.4 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KEY70344.1 - 1.8e-09 38.0 0.0 2.4e-07 31.1 0.0 2.5 1 1 1 2 2 2 2 Tyrosine phosphatase family DSPc PF00782.15 KEY70344.1 - 0.00064 19.3 0.0 0.00093 18.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEY70344.1 - 0.001 18.4 0.2 0.0024 17.2 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PrsW-protease PF13367.1 KEY70345.1 - 0.064 12.4 0.3 0.1 11.7 0.1 1.4 1 1 0 1 1 1 0 Protease prsW family DUF2416 PF10315.4 KEY70345.1 - 0.17 12.1 0.9 0.35 11.1 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2416) Zn_clus PF00172.13 KEY70346.1 - 6.4e-07 29.1 10.9 9.9e-07 28.5 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF566 PF04484.7 KEY70346.1 - 3.7 6.9 9.1 4.9 6.5 6.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Pho88 PF10032.4 KEY70347.1 - 1.6e-78 262.3 0.4 1.8e-78 262.1 0.3 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF1240 PF06836.7 KEY70347.1 - 0.14 12.4 1.2 0.38 11.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) XPA_C PF05181.7 KEY70348.1 - 5.9e-29 99.4 2.6 1.6e-28 98.0 1.8 1.8 1 0 0 1 1 1 1 XPA protein C-terminus zf-C3HC4_3 PF13920.1 KEY70348.1 - 0.094 12.3 7.0 0.038 13.6 2.6 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FRG1 PF06229.7 KEY70348.1 - 1.1 8.6 6.3 0.14 11.5 0.8 2.0 2 0 0 2 2 2 0 FRG1-like family Ras PF00071.17 KEY70349.1 - 4.2e-05 23.0 0.0 0.0015 17.9 0.0 2.0 2 0 0 2 2 2 2 Ras family DAO PF01266.19 KEY70350.1 - 3.7e-31 108.3 1.7 7.4e-31 107.3 1.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEY70350.1 - 7.5e-05 22.8 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 KEY70350.1 - 0.0057 14.8 0.0 0.0086 14.2 0.0 1.1 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.1 KEY70350.1 - 0.0078 16.2 0.1 0.023 14.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEY70350.1 - 0.047 12.5 4.1 0.099 11.4 2.8 1.6 1 1 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KEY70350.1 - 0.069 12.2 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 KEY70350.1 - 0.094 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TPR_19 PF14559.1 KEY70350.1 - 0.11 12.8 0.0 6.4 7.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat IPK PF03770.11 KEY70352.1 - 1.2e-54 184.9 0.0 2.2e-54 184.1 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase LRR_4 PF12799.2 KEY70354.1 - 9.5e-35 117.6 33.1 3.4e-08 32.9 1.5 7.6 8 0 0 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEY70354.1 - 2.2e-19 68.9 42.5 7.4e-06 25.6 2.3 7.3 6 1 2 8 8 8 7 Leucine rich repeat LRR_1 PF00560.28 KEY70354.1 - 4.5e-12 44.2 32.5 0.96 9.7 0.1 13.0 11 2 0 11 11 11 4 Leucine Rich Repeat LRR_6 PF13516.1 KEY70354.1 - 7.1e-08 31.7 28.3 1.1 9.5 0.0 10.5 9 3 2 11 11 11 3 Leucine Rich repeat LRR_9 PF14580.1 KEY70354.1 - 1.3e-06 28.0 8.9 0.13 11.8 0.3 4.9 2 1 2 4 4 4 3 Leucine-rich repeat LRR_7 PF13504.1 KEY70354.1 - 4.7e-05 22.9 42.5 9 7.0 0.0 13.4 14 0 0 14 14 14 3 Leucine rich repeat Aconitase PF00330.15 KEY70355.1 - 6.7e-75 252.3 0.1 1.9e-48 165.1 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KEY70355.1 - 6.6e-20 71.5 0.0 1.1e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain RabGAP-TBC PF00566.13 KEY70356.1 - 1.1e-46 158.9 0.1 1.7e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PIG-L PF02585.12 KEY70356.1 - 0.8 10.2 3.3 1.6 9.2 0.1 2.8 3 0 0 3 3 3 0 GlcNAc-PI de-N-acetylase ECH PF00378.15 KEY70357.1 - 4e-10 39.2 0.0 2.3e-08 33.4 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF594 PF04578.8 KEY70357.1 - 0.05 13.0 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF594 DDE_Tnp_1_7 PF13843.1 KEY70358.1 - 1.7e-21 76.6 0.0 1.9e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 Dimer_Tnp_hAT PF05699.9 KEY70359.1 - 5.4e-18 64.3 0.2 1.7e-17 62.8 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Tyrosinase PF00264.15 KEY70360.1 - 2.2e-51 175.1 4.4 3.3e-51 174.5 3.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase RNA_pol_Rpb2_6 PF00562.23 KEY70361.1 - 5.8e-113 377.5 0.1 7.6e-113 377.1 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KEY70361.1 - 7.1e-30 103.4 0.0 1e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 KEY70361.1 - 8.3e-25 86.3 0.0 2.6e-24 84.7 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 KEY70361.1 - 5.7e-24 84.5 0.0 1e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 KEY70361.1 - 2.6e-22 78.5 0.5 6.6e-22 77.2 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 KEY70361.1 - 9.5e-15 54.6 0.0 5e-14 52.3 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 KEY70361.1 - 0.0023 17.8 0.0 0.0053 16.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Rpr2 PF04032.11 KEY70361.1 - 0.037 13.8 0.7 0.081 12.7 0.5 1.4 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Arf PF00025.16 KEY70362.1 - 5.4e-29 100.6 0.0 5.8e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KEY70362.1 - 6e-13 48.4 0.0 7.2e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEY70362.1 - 1.3e-05 25.6 0.0 7e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 KEY70362.1 - 3.4e-05 23.0 0.0 3.9e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KEY70362.1 - 6e-05 22.5 0.0 6.8e-05 22.3 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 KEY70362.1 - 0.00084 18.1 0.2 0.0011 17.6 0.1 1.5 1 1 0 1 1 1 1 G-protein alpha subunit Beta_elim_lyase PF01212.16 KEY70363.1 - 1.6e-64 217.8 0.0 2.2e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KEY70363.1 - 0.0008 18.4 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KEY70363.1 - 0.0062 15.6 0.1 0.013 14.5 0.1 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KEY70363.1 - 0.021 13.5 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V MR_MLE_C PF13378.1 KEY70363.1 - 0.13 12.1 0.9 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 Enolase C-terminal domain-like tRNA-synt_2 PF00152.15 KEY70364.1 - 8.1e-70 235.2 0.0 1e-69 234.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KEY70364.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain 2OG-FeII_Oxy_3 PF13640.1 KEY70366.1 - 0.01 16.3 0.0 0.018 15.5 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Trehalase PF01204.13 KEY70367.1 - 1e-111 374.1 0.4 4.2e-111 372.0 0.3 1.7 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.9 KEY70367.1 - 2.5e-05 23.1 0.3 0.0022 16.8 0.0 2.2 2 0 0 2 2 2 2 Amylo-alpha-1,6-glucosidase Glyco_hydro_43 PF04616.9 KEY70368.1 - 2e-54 184.6 5.0 2.5e-54 184.2 3.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DHO_dh PF01180.16 KEY70371.1 - 4e-23 81.8 0.0 5.3e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase MFS_1 PF07690.11 KEY70372.1 - 2.1e-08 33.2 17.7 2.1e-08 33.2 12.3 4.2 3 2 1 4 4 4 3 Major Facilitator Superfamily PHO4 PF01384.15 KEY70373.1 - 5.3e-108 360.5 21.4 6.3e-108 360.2 14.8 1.0 1 0 0 1 1 1 1 Phosphate transporter family Fungal_trans PF04082.13 KEY70374.1 - 4.6e-27 94.5 0.0 6.8e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY70374.1 - 5.1e-06 26.2 15.4 9.5e-06 25.4 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.15 KEY70376.1 - 1.5e-16 61.0 0.0 2.3e-15 57.0 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KEY70376.1 - 2.2e-12 46.6 0.0 1.1e-11 44.3 0.0 2.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KEY70376.1 - 5.4e-08 32.4 0.5 0.0028 16.9 0.0 2.6 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KEY70376.1 - 3.6e-06 27.2 0.7 0.088 12.8 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase YbaJ PF10757.4 KEY70376.1 - 0.016 15.3 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 Biofilm formation regulator YbaJ Epimerase PF01370.16 KEY70378.1 - 2.6e-20 72.8 0.0 3.9e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEY70378.1 - 9.4e-17 60.6 0.0 1.2e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KEY70378.1 - 5.7e-14 52.5 0.1 1.3e-13 51.3 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KEY70378.1 - 4e-12 46.3 0.1 8.6e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KEY70378.1 - 6.2e-12 44.9 0.2 1.9e-10 40.1 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 KEY70378.1 - 5.1e-09 36.0 0.0 8.3e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KEY70378.1 - 8e-06 24.9 0.1 1.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KEY70378.1 - 0.00031 20.0 0.1 0.00052 19.3 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 KEY70378.1 - 0.0071 15.2 0.0 0.021 13.7 0.0 1.9 2 1 0 2 2 2 1 RmlD substrate binding domain Saccharop_dh PF03435.13 KEY70378.1 - 0.0075 15.2 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KEY70378.1 - 0.017 15.4 0.1 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short_C2 PF13561.1 KEY70378.1 - 0.054 13.2 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.21 KEY70379.1 - 1.8e-19 69.5 0.0 3.3e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY70379.1 - 4e-09 37.4 0.0 8.1e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GMC_oxred_N PF00732.14 KEY70380.1 - 6.5e-52 176.5 0.0 8.5e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY70380.1 - 9.9e-30 103.7 0.0 1.7e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KEY70380.1 - 8.2e-06 24.9 0.0 0.033 13.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY70380.1 - 0.0004 20.3 0.0 0.0013 18.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEY70380.1 - 0.00062 19.8 0.0 0.87 9.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY70380.1 - 0.0032 16.4 0.1 0.0066 15.4 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KEY70380.1 - 0.0048 15.7 0.1 0.32 9.7 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KEY70380.1 - 0.018 14.9 0.1 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEY70380.1 - 0.021 13.3 0.2 1.4 7.2 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein p450 PF00067.17 KEY70381.1 - 3.7e-65 220.2 0.0 4.3e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KEY70382.1 - 4.8e-35 120.9 36.0 8e-35 120.1 24.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY70382.1 - 9.9e-11 40.8 10.4 9.9e-11 40.8 7.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 KEY70382.1 - 1.1 7.2 8.7 66 1.3 6.0 2.2 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_3 PF01494.14 KEY70383.1 - 1.8e-09 37.1 0.3 0.00049 19.2 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain GFO_IDH_MocA PF01408.17 KEY70384.1 - 6e-16 59.0 0.0 1.3e-15 58.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ketoacyl-synt PF00109.21 KEY70385.1 - 4.6e-72 242.5 0.3 9.8e-72 241.4 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEY70385.1 - 4.5e-34 118.2 1.1 1.3e-30 106.8 1.0 2.3 2 0 0 2 2 2 2 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KEY70385.1 - 1.7e-31 108.5 0.0 4e-31 107.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 KEY70385.1 - 1.3e-29 103.3 1.4 2.5e-29 102.4 1.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 KEY70385.1 - 8.6e-09 35.5 1.9 0.0011 19.1 0.6 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thiolase_N PF00108.18 KEY70385.1 - 8.5e-06 24.9 0.1 1.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain FAD_syn PF06574.7 KEY70385.1 - 0.14 11.7 0.0 1.2 8.7 0.0 2.2 1 1 0 2 2 2 0 FAD synthetase DUF773 PF05600.7 KEY70385.1 - 0.63 8.7 0.0 0.97 8.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF773) DUF658 PF04936.7 KEY70386.1 - 0.074 12.9 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF658) FAD_binding_4 PF01565.18 KEY70387.1 - 9.4e-25 86.7 0.1 2.7e-24 85.2 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain Transferase PF02458.10 KEY70387.1 - 5.1e-17 61.4 0.0 1.9e-16 59.5 0.0 1.8 1 1 1 2 2 2 1 Transferase family BBE PF08031.7 KEY70387.1 - 1.2e-05 25.1 0.0 2.7e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like ketoacyl-synt PF00109.21 KEY70388.1 - 1.3e-70 237.7 0.3 1.3e-70 237.7 0.2 2.2 3 0 0 3 3 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEY70388.1 - 6.4e-33 114.4 0.0 1.1e-32 113.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KEY70388.1 - 5.4e-29 100.4 0.0 1.1e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KEY70388.1 - 1.4e-24 86.3 0.0 2.5e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 KEY70388.1 - 2.2e-13 50.5 0.0 5.2e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KEY70388.1 - 8.4e-12 45.1 0.9 1.9e-11 44.0 0.6 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 KEY70388.1 - 1.2e-07 31.7 0.3 7.3e-06 26.0 0.1 3.4 4 0 0 4 4 4 1 short chain dehydrogenase Thiolase_N PF00108.18 KEY70388.1 - 3.4e-07 29.5 0.1 1e-06 27.9 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.1 KEY70388.1 - 6.8e-06 25.7 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY70388.1 - 7.8e-06 26.3 0.0 2e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY70388.1 - 3e-05 23.8 0.0 0.00019 21.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain KR PF08659.5 KEY70388.1 - 4.3e-05 23.2 0.2 0.00017 21.3 0.1 2.1 2 0 0 2 2 2 1 KR domain Ubie_methyltran PF01209.13 KEY70388.1 - 0.00015 20.9 0.0 0.00035 19.7 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Epimerase PF01370.16 KEY70388.1 - 0.00017 21.1 0.0 0.00035 20.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 KEY70388.1 - 0.00076 20.0 0.0 0.0048 17.4 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 KEY70388.1 - 0.057 12.3 0.0 0.54 9.1 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KEY70388.1 - 0.31 9.6 0.0 3.6 6.2 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans PF04082.13 KEY70389.1 - 2.3e-18 66.0 1.5 4.5e-18 65.0 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY70389.1 - 2.8e-06 27.1 12.4 2.8e-06 27.1 8.6 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_fiss_reg PF05308.6 KEY70389.1 - 0.019 14.3 0.3 0.037 13.4 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF1308 PF07000.6 KEY70389.1 - 0.12 11.0 0.8 0.5 8.9 0.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1308) FlxA PF14282.1 KEY70389.1 - 0.17 11.8 0.0 0.17 11.8 0.0 2.4 3 0 0 3 3 3 0 FlxA-like protein Dickkopf_N PF04706.7 KEY70389.1 - 0.29 11.3 8.0 0.94 9.6 5.5 1.9 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region DUF974 PF06159.8 KEY70390.1 - 9.3e-85 284.0 0.0 1.2e-84 283.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) KH_1 PF00013.24 KEY70391.1 - 1.9e-11 43.4 0.0 3.1e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 KEY70391.1 - 5e-08 32.4 0.8 1.3e-05 24.6 0.0 3.1 3 0 0 3 3 3 2 KH domain Trp_repressor PF01371.14 KEY70391.1 - 0.13 12.1 0.1 2.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Trp repressor protein ALS_ss_C PF10369.4 KEY70392.1 - 2.6e-18 65.4 0.0 3.3e-17 61.9 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 KEY70392.1 - 1e-11 44.0 0.1 2e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 KEY70392.1 - 6.2e-09 35.5 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 KEY70392.1 - 0.057 13.1 0.1 9.9 5.9 0.0 2.6 2 0 0 2 2 2 0 ACT domain OTCace_N PF02729.16 KEY70393.1 - 8.3e-42 142.2 0.1 1.2e-41 141.7 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 KEY70393.1 - 3.2e-40 137.5 0.0 7.3e-40 136.4 0.0 1.6 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF3712 PF12505.3 KEY70394.1 - 3.2e-07 30.4 1.4 3.2e-06 27.2 0.8 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) OppC_N PF12911.2 KEY70394.1 - 0.16 11.3 2.5 0.37 10.1 1.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C TYA PF01021.14 KEY70394.1 - 0.38 10.9 1.9 3 8.1 0.3 2.4 2 0 0 2 2 2 0 TYA transposon protein SART-1 PF03343.8 KEY70395.1 - 1.9e-155 518.7 55.9 2.2e-155 518.4 38.8 1.0 1 0 0 1 1 1 1 SART-1 family SNAP PF14938.1 KEY70396.1 - 2.4e-114 381.2 18.3 2.7e-114 381.1 12.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KEY70396.1 - 1.5e-05 24.8 17.7 0.0026 17.6 1.9 3.9 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEY70396.1 - 0.0031 17.2 21.8 0.065 13.1 0.2 7.0 6 2 2 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEY70396.1 - 0.0049 16.5 8.0 0.89 9.4 0.4 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEY70396.1 - 0.01 15.4 1.6 0.01 15.4 1.1 4.1 2 1 2 4 4 4 0 TPR repeat TPR_1 PF00515.23 KEY70396.1 - 0.013 15.0 10.5 0.17 11.5 0.2 5.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEY70396.1 - 0.036 13.8 10.3 12 5.9 0.1 5.3 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEY70396.1 - 0.04 14.3 15.0 13 6.5 0.1 6.2 5 1 3 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.1 KEY70396.1 - 0.13 12.6 0.1 0.13 12.6 0.1 4.1 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEY70396.1 - 0.17 12.6 22.3 0.25 12.0 0.2 4.9 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEY70396.1 - 0.59 10.9 15.8 27 5.7 0.0 6.1 4 2 3 7 7 7 0 Tetratricopeptide repeat Apc3 PF12895.2 KEY70396.1 - 1.9 8.6 9.1 0.53 10.4 1.0 3.3 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Glu-tRNAGln PF02686.10 KEY70397.1 - 3.4e-05 23.5 0.5 0.00048 19.8 0.4 2.1 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit PPI_Ypi1 PF07491.6 KEY70398.1 - 8.1e-19 67.0 6.5 1.1e-10 40.9 0.1 2.5 2 0 0 2 2 2 2 Protein phosphatase inhibitor MMR_HSR1 PF01926.18 KEY70399.1 - 5.6e-06 26.3 0.0 3.2e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase L51_S25_CI-B8 PF05047.11 KEY70400.1 - 5.8e-16 57.9 0.2 1.1e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain HECT PF00632.20 KEY70401.1 - 4.3e-76 256.0 0.0 6.6e-76 255.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF3712 PF12505.3 KEY70402.1 - 5.8e-07 29.5 0.0 2.9e-06 27.3 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3712) ADH_N PF08240.7 KEY70403.1 - 8.1e-34 115.6 2.1 2.2e-33 114.2 1.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY70403.1 - 4.3e-16 58.6 0.0 7e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY70403.1 - 1.1e-05 26.3 0.0 2.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 KEY70403.1 - 0.0025 16.9 0.1 0.0039 16.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Methyltransf_18 PF12847.2 KEY70403.1 - 0.0053 17.3 0.0 0.01 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Saccharop_dh PF03435.13 KEY70403.1 - 0.032 13.1 0.0 0.039 12.9 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase XdhC_C PF13478.1 KEY70403.1 - 0.086 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_8 PF13450.1 KEY70403.1 - 0.11 12.5 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF2338 PF10100.4 KEY70403.1 - 0.12 10.7 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) S10_plectin PF03501.10 KEY70404.1 - 5.9e-38 128.6 0.1 7.2e-38 128.3 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Telomere_Sde2 PF13019.1 KEY70405.1 - 1.9e-65 219.5 0.4 3e-65 218.8 0.3 1.3 1 0 0 1 1 1 1 Telomere stability and silencing DUF2407 PF10302.4 KEY70405.1 - 2.9 8.1 9.7 48 4.2 0.0 3.2 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain COX6B PF02297.12 KEY70406.1 - 2.3e-18 65.9 3.0 2.9e-18 65.6 2.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 KEY70406.1 - 0.0046 16.3 0.3 0.0088 15.4 0.2 1.5 1 0 0 1 1 1 1 APOBEC-like C-terminal domain B12D PF06522.6 KEY70407.1 - 1.1e-05 24.9 0.1 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.17 KEY70408.1 - 1.9e-17 62.6 0.0 2.5e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY70408.1 - 1.9e-11 43.7 0.0 2.5e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY70408.1 - 2.3e-10 40.1 0.0 3.4e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEY70408.1 - 0.0059 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif WD40 PF00400.27 KEY70409.1 - 6.4e-19 67.0 2.1 0.00086 19.1 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat SRA1 PF07304.6 KEY70409.1 - 5e-11 42.5 0.0 1.6e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 KEY70409.1 - 2e-09 37.6 0.1 5.1e-09 36.2 0.1 1.7 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Apc4_WD40 PF12894.2 KEY70409.1 - 0.19 11.2 0.0 1.5 8.3 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ferritin_2 PF13668.1 KEY70410.1 - 0.016 15.1 0.6 0.024 14.5 0.4 1.3 1 0 0 1 1 1 0 Ferritin-like domain GET2 PF08690.5 KEY70411.1 - 4.7e-15 55.6 0.1 1.2e-13 51.0 0.0 2.4 1 1 0 1 1 1 1 GET complex subunit GET2 DUF2863 PF11062.3 KEY70412.1 - 0.14 10.1 0.0 0.22 9.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) HLH PF00010.21 KEY70413.1 - 0.0009 18.8 0.0 0.0009 18.8 0.0 2.5 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain TIP49 PF06068.8 KEY70414.1 - 1.8e-175 583.4 2.9 2.1e-175 583.2 2.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 KEY70414.1 - 7.6e-09 34.9 0.5 4.9e-05 22.4 0.0 2.9 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 KEY70414.1 - 2.7e-08 34.0 1.1 3.4e-05 24.0 0.0 3.3 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 KEY70414.1 - 8.5e-07 28.1 0.6 1.6e-06 27.2 0.4 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 KEY70414.1 - 0.00015 21.7 0.0 0.0015 18.5 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEY70414.1 - 0.00032 20.8 0.0 0.28 11.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KEY70414.1 - 0.00067 18.8 0.6 0.019 14.1 0.2 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KEY70414.1 - 0.0013 18.6 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KEY70414.1 - 0.0072 16.0 0.5 3 7.5 0.0 3.5 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KEY70414.1 - 0.014 14.8 0.1 0.033 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KEY70414.1 - 0.016 14.6 0.0 5.4 6.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 KEY70414.1 - 0.036 13.8 0.5 0.13 12.0 0.2 2.0 1 1 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 KEY70414.1 - 0.068 13.4 0.0 0.59 10.4 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KEY70414.1 - 0.083 12.4 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KEY70414.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 KEY70414.1 - 0.11 11.3 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Fib_alpha PF08702.5 KEY70416.1 - 0.0046 17.0 21.5 0.0089 16.1 2.9 4.6 3 1 3 6 6 6 2 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 KEY70416.1 - 0.007 15.5 5.1 0.007 15.5 3.5 3.9 1 1 3 5 5 5 1 Reovirus sigma C capsid protein DUF4615 PF15393.1 KEY70416.1 - 0.22 11.7 9.7 0.041 14.1 2.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4615) Surfac_D-trimer PF09006.6 KEY70416.1 - 0.24 11.1 2.2 5.3 6.8 0.1 3.2 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Atg14 PF10186.4 KEY70416.1 - 1.3 7.8 33.4 0.68 8.8 1.8 3.4 1 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Baculo_PEP_C PF04513.7 KEY70416.1 - 2 8.2 21.6 2.2 8.0 0.1 5.2 3 2 3 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.7 KEY70416.1 - 2.6 8.4 26.7 1.7 9.0 0.3 6.6 5 2 0 6 6 6 0 SlyX Phage_GPO PF05929.6 KEY70416.1 - 3.3 6.8 29.3 0.15 11.3 0.4 4.4 2 2 1 4 4 4 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF1664 PF07889.7 KEY70416.1 - 6.4 6.5 13.8 31 4.3 1.7 4.8 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) DUF3584 PF12128.3 KEY70416.1 - 9.3 3.4 42.3 0.083 10.2 2.7 3.9 1 1 2 4 4 4 0 Protein of unknown function (DUF3584) Gp_dh_C PF02800.15 KEY70418.1 - 9.1e-76 252.6 0.1 1.3e-75 252.1 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KEY70418.1 - 6.1e-59 198.3 0.1 1e-58 197.5 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 KEY70418.1 - 0.0016 18.3 0.5 0.0047 16.8 0.0 2.1 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 KEY70418.1 - 0.062 12.4 0.1 0.36 9.9 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GYF PF02213.11 KEY70419.1 - 6.1e-11 41.7 0.3 1.3e-10 40.7 0.2 1.6 1 0 0 1 1 1 1 GYF domain Gluconate_2-dh3 PF13618.1 KEY70419.1 - 0.4 10.8 5.0 5.6 7.1 3.4 2.4 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 UFD1 PF03152.9 KEY70420.1 - 1.5e-66 222.8 0.0 2e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Sec62 PF03839.11 KEY70421.1 - 0.85 8.9 5.9 1.1 8.6 4.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 HTH_12 PF08461.5 KEY70423.1 - 0.0012 18.5 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease R winged-helix domain Collagen PF01391.13 KEY70424.1 - 1.5 8.4 12.4 2.9 7.4 8.6 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) PAT1 PF09770.4 KEY70424.1 - 4.6 5.3 8.7 5.4 5.1 6.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2477 PF10631.4 KEY70426.1 - 0.26 11.5 2.2 0.34 11.1 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) Sec16_N PF12935.2 KEY70428.1 - 0.038 13.8 16.5 0.3 10.9 11.4 2.0 1 1 0 1 1 1 0 Vesicle coat trafficking protein Sec16 N-terminus DUF932 PF06067.6 KEY70428.1 - 0.05 12.9 0.3 0.075 12.3 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF932) SAGA-Tad1 PF12767.2 KEY70428.1 - 0.2 11.2 7.8 0.27 10.8 5.4 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Paramyxo_ncap PF00973.14 KEY70428.1 - 0.23 10.1 2.5 0.26 9.9 1.7 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Ebola_NP PF05505.7 KEY70428.1 - 4.7 5.1 13.5 5.4 4.9 9.4 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein APG6 PF04111.7 KEY70429.1 - 0.017 14.2 1.3 0.027 13.5 0.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4140 PF13600.1 KEY70429.1 - 0.067 13.6 0.4 0.18 12.2 0.3 1.7 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 KEY70429.1 - 0.32 11.3 3.0 0.97 9.8 2.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Cpn60_TCP1 PF00118.19 KEY70431.1 - 3.6e-119 398.5 9.2 4.8e-119 398.1 6.4 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cofilin_ADF PF00241.15 KEY70431.1 - 3.1e-32 111.1 0.5 5.6e-32 110.3 0.4 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Blt1 PF12754.2 KEY70432.1 - 3.7e-38 131.8 4.2 7.2e-31 107.9 0.2 2.1 1 1 1 2 2 2 2 Cell-cycle control medial ring component ubiquitin PF00240.18 KEY70432.1 - 0.058 12.7 0.1 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family Nol1_Nop2_Fmu PF01189.12 KEY70433.1 - 3.2e-97 325.2 0.0 4.9e-97 324.7 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 KEY70433.1 - 0.0011 19.0 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 KEY70433.1 - 0.013 16.0 0.0 0.047 14.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 KEY70433.1 - 0.02 14.4 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 KEY70433.1 - 0.072 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.14 KEY70433.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) XRCC4 PF06632.7 KEY70435.1 - 0.0042 15.9 14.0 0.022 13.6 9.7 1.9 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Mnd1 PF03962.10 KEY70435.1 - 0.43 10.2 4.6 0.34 10.5 2.0 1.7 1 1 0 1 1 1 0 Mnd1 family NOA36 PF06524.7 KEY70435.1 - 5.3 6.2 7.4 8.4 5.5 5.1 1.3 1 0 0 1 1 1 0 NOA36 protein Aldo_ket_red PF00248.16 KEY70436.1 - 3e-47 160.7 0.0 4.3e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.9 KEY70437.1 - 2.7e-116 388.7 0.0 3.4e-116 388.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Molybdopterin PF00384.17 KEY70438.1 - 4.6e-74 249.6 0.0 3.3e-72 243.5 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 KEY70438.1 - 3.3e-19 68.4 0.2 8.6e-19 67.1 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 KEY70438.1 - 1.2e-18 65.9 0.1 3e-18 64.7 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 KEY70438.1 - 8.7e-16 57.8 0.0 2.4e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 KEY70438.1 - 1.7e-08 34.0 0.6 1.7e-08 34.0 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 KEY70438.1 - 0.0037 17.0 0.0 0.084 12.6 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CNTF PF01110.12 KEY70439.1 - 0.049 12.9 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor ACBP PF00887.14 KEY70440.1 - 2.4e-29 100.8 0.0 4.7e-29 99.9 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Atg14 PF10186.4 KEY70440.1 - 0.59 9.0 4.7 3.8 6.3 1.7 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Ribonuclease_3 PF00636.21 KEY70441.1 - 1.1e-15 58.0 0.3 8.3e-15 55.2 0.0 2.5 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KEY70441.1 - 3.5e-10 39.9 0.0 2.9e-09 36.9 0.0 2.2 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.20 KEY70441.1 - 1.8e-06 28.3 0.0 4.4e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif NEP PF10167.4 KEY70441.1 - 0.22 11.2 1.6 1 9.0 0.2 2.4 1 1 1 2 2 2 0 Uncharacterised conserved protein MRP-S33 PF08293.6 KEY70442.1 - 3.1e-26 91.1 0.1 3.9e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 PUF PF00806.14 KEY70444.1 - 4.2e-31 104.6 4.0 5.4e-06 25.5 0.0 8.4 9 0 0 9 9 9 6 Pumilio-family RNA binding repeat DUF3573 PF12097.3 KEY70444.1 - 0.12 10.9 0.1 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) PP2C PF00481.16 KEY70445.1 - 2.2e-41 141.9 0.0 3.4e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KEY70445.1 - 0.0005 19.5 0.0 0.0011 18.4 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KEY70445.1 - 0.0015 18.2 0.2 0.12 12.1 0.0 2.8 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) Glyco_hydro_47 PF01532.15 KEY70447.1 - 3.3e-158 527.0 0.0 3.8e-158 526.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 KEY70447.1 - 0.0028 15.9 0.0 0.82 7.8 0.0 2.3 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) CactinC_cactus PF09732.4 KEY70447.1 - 0.069 12.7 0.0 0.34 10.5 0.0 2.1 2 0 0 2 2 2 0 Cactus-binding C-terminus of cactin protein Glycos_transf_1 PF00534.15 KEY70448.1 - 1.8e-31 108.8 0.0 2.9e-18 65.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KEY70448.1 - 3e-07 30.7 9.4 3e-07 30.7 6.5 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 KEY70448.1 - 2.1e-06 27.5 0.1 0.012 15.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 KEY70448.1 - 1.3e-05 25.3 0.3 0.0041 17.2 0.0 3.1 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KEY70448.1 - 0.00025 21.2 0.0 0.00052 20.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Bd3614_N PF14442.1 KEY70448.1 - 0.39 10.6 5.2 0.38 10.7 1.6 2.1 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal Pkinase PF00069.20 KEY70449.1 - 5.5e-52 176.4 0.1 2.6e-36 125.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEY70449.1 - 1.4e-21 76.8 0.4 4.4e-20 71.8 0.3 2.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY70449.1 - 1.1e-05 24.5 0.0 2.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEY70449.1 - 0.012 15.3 2.0 0.019 14.7 0.1 2.2 3 0 0 3 3 3 0 Phosphotransferase enzyme family Chorismate_synt PF01264.16 KEY70451.1 - 3.2e-109 364.5 0.0 2.6e-87 292.5 0.0 2.0 1 1 1 2 2 2 2 Chorismate synthase Hormone_4 PF00220.12 KEY70451.1 - 1 9.2 3.2 2.7 7.8 2.2 1.8 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain BPL_LplA_LipB PF03099.14 KEY70452.1 - 2.8e-14 53.2 0.0 7.5e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Fungal_trans_2 PF11951.3 KEY70454.1 - 1.3e-58 198.4 0.0 1.7e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY70454.1 - 0.00014 21.6 8.5 0.00027 20.7 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF948 PF06103.6 KEY70455.1 - 1 9.2 2.5 0.58 10.0 0.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Abhydrolase_3 PF07859.8 KEY70457.1 - 6.6e-35 120.6 0.2 8.6e-35 120.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KEY70457.1 - 2e-05 23.5 0.2 4.1e-05 22.4 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KEY70457.1 - 0.0013 18.0 0.2 0.0027 16.9 0.2 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Thioesterase PF00975.15 KEY70457.1 - 0.0075 16.5 0.1 0.012 15.8 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.15 KEY70457.1 - 0.0097 15.3 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KEY70457.1 - 0.013 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KEY70457.1 - 0.094 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme BC10 PF06726.7 KEY70459.1 - 1.7e-18 66.3 11.0 3e-18 65.6 7.6 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 PAP2_3 PF14378.1 KEY70461.1 - 2.4e-38 131.6 10.7 2.4e-38 131.6 7.4 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 KEY70461.1 - 0.00018 21.6 0.1 0.00018 21.6 0.1 2.5 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.16 KEY70461.1 - 0.0027 17.3 9.1 0.0027 17.3 6.3 2.4 1 1 1 2 2 2 1 PAP2 superfamily ADH_zinc_N PF00107.21 KEY70462.1 - 1.3e-19 70.0 0.0 2.7e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY70462.1 - 2.9e-19 70.2 0.0 6.9e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase R3H PF01424.17 KEY70462.1 - 5.4e-10 38.8 0.0 1.1e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 R3H domain ADH_N PF08240.7 KEY70462.1 - 1e-07 31.6 0.1 1.9e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain RRM_6 PF14259.1 KEY70462.1 - 5.6e-07 29.4 0.1 1.1e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY70462.1 - 7.5e-06 25.6 0.1 1.7e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEY70462.1 - 4.7e-05 22.9 0.1 0.00011 21.8 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KEY70462.1 - 0.15 11.8 0.3 0.39 10.5 0.2 1.6 1 0 0 1 1 1 0 Limkain b1 Methyltransf_12 PF08242.7 KEY70463.1 - 0.0047 17.3 0.0 0.016 15.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DUF3632 PF12311.3 KEY70464.1 - 5.6e-27 94.7 0.1 7.7e-27 94.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Mito_fiss_reg PF05308.6 KEY70465.1 - 0.79 9.0 8.0 1.2 8.4 5.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Methyltransf_16 PF10294.4 KEY70467.1 - 1.8e-22 79.6 0.0 2.5e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KEY70467.1 - 0.0037 17.0 0.0 0.0056 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Fer4_13 PF13370.1 KEY70469.1 - 0.036 14.4 4.1 21 5.5 0.1 4.4 4 0 0 4 4 4 0 4Fe-4S single cluster domain RNA_pol_N PF01194.12 KEY70470.1 - 1e-28 99.0 1.1 1.4e-28 98.7 0.8 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 KEY70470.1 - 0.12 12.4 0.2 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Mqo PF06039.10 KEY70470.1 - 0.14 10.3 0.0 0.18 9.9 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) DIOX_N PF14226.1 KEY70471.1 - 2.6e-29 102.0 0.0 1.4e-28 99.7 0.0 2.2 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KEY70471.1 - 4e-13 49.5 0.0 1.6e-12 47.5 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 KEY70471.1 - 1.6e-09 37.2 1.8 3.8e-05 23.3 0.1 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat 4F5 PF04419.9 KEY70472.1 - 2.4e-08 34.5 11.8 3.1e-08 34.1 8.1 1.1 1 0 0 1 1 1 1 4F5 protein family zf-met2 PF12907.2 KEY70472.1 - 8.9e-05 22.3 2.1 9.9e-05 22.2 0.5 1.7 2 0 0 2 2 2 1 Zinc-binding DUF4057 PF13266.1 KEY70472.1 - 0.096 12.1 0.2 0.1 12.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4057) Phage_Capsid_P3 PF09018.6 KEY70472.1 - 0.11 11.1 0.1 0.12 10.9 0.1 1.0 1 0 0 1 1 1 0 P3 major capsid protein DUF2570 PF10828.3 KEY70472.1 - 0.2 11.2 2.3 0.24 10.9 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF1479 PF07350.7 KEY70474.1 - 4.1e-145 483.4 0.0 4.8e-145 483.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Bap31 PF05529.7 KEY70475.1 - 3.8e-63 212.4 6.1 4.3e-63 212.2 4.2 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF192 PF02643.10 KEY70475.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized ACR, COG1430 Mod_r PF07200.8 KEY70475.1 - 0.011 15.6 2.3 0.017 15.0 1.6 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.6 KEY70475.1 - 0.017 13.7 1.6 0.024 13.3 1.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DEDD_Tnp_IS110 PF01548.12 KEY70475.1 - 0.023 14.3 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Transposase CCDC-167 PF15188.1 KEY70475.1 - 0.024 14.5 1.3 0.056 13.3 0.9 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DivIC PF04977.10 KEY70475.1 - 0.082 12.4 7.0 0.057 12.9 1.3 2.9 3 0 0 3 3 3 0 Septum formation initiator Viral_P18 PF04521.8 KEY70475.1 - 0.11 11.9 0.9 0.17 11.3 0.6 1.3 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein Spc24 PF08286.6 KEY70475.1 - 0.11 12.1 1.4 0.23 11.1 0.9 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 IncA PF04156.9 KEY70475.1 - 0.17 11.4 2.0 0.3 10.6 1.4 1.4 1 0 0 1 1 1 0 IncA protein DUF1385 PF07136.6 KEY70475.1 - 5.6 5.9 10.2 8.5 5.3 5.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) SET PF00856.23 KEY70476.1 - 3.1e-22 79.6 1.3 3e-21 76.3 0.1 3.2 3 1 0 3 3 3 1 SET domain Pil1 PF13805.1 KEY70477.1 - 2.2e-154 512.3 0.2 2.7e-154 512.0 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 KEY70477.1 - 0.021 14.1 2.0 0.056 12.7 1.4 1.8 1 1 0 1 1 1 0 FAM92 protein Gas_vesicle_C PF01304.12 KEY70477.1 - 0.12 11.9 0.1 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain APG6 PF04111.7 KEY70477.1 - 0.69 8.8 3.2 8.5 5.3 0.8 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 LSM PF01423.17 KEY70478.1 - 2.2e-08 33.4 0.0 2.8e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KEY70478.1 - 0.0007 19.4 0.0 0.0015 18.3 0.0 1.6 1 1 0 1 1 1 1 Ataxin 2 SM domain FimH_man-bind PF09160.5 KEY70478.1 - 0.089 12.6 0.0 0.099 12.4 0.0 1.0 1 0 0 1 1 1 0 FimH, mannose binding XPG_N PF00752.12 KEY70479.1 - 5.1e-32 110.1 0.0 1.2e-31 108.9 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KEY70479.1 - 1.3e-27 95.6 0.0 3.3e-27 94.3 0.0 1.8 1 0 0 1 1 1 1 XPG I-region UIM PF02809.15 KEY70479.1 - 0.00092 18.5 0.1 0.0089 15.5 0.1 2.9 1 0 0 1 1 1 1 Ubiquitin interaction motif XPG_I_2 PF12813.2 KEY70479.1 - 0.0011 18.4 0.0 0.0037 16.8 0.0 1.9 1 0 0 1 1 1 1 XPG domain containing F-box-like PF12937.2 KEY70480.1 - 4.3e-08 32.7 1.3 7.8e-08 31.9 0.9 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEY70480.1 - 2.9e-06 26.7 1.2 5.9e-06 25.7 0.8 1.6 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 KEY70480.1 - 0.16 11.9 0.1 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 PRANC domain HET PF06985.6 KEY70481.1 - 3.1e-23 82.4 0.0 6.9e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Endothelin PF00322.12 KEY70481.1 - 0.95 8.7 4.2 3.7 6.8 0.3 2.6 2 0 0 2 2 2 0 Endothelin family HSP70 PF00012.15 KEY70482.1 - 1.3e-230 766.4 5.6 1.5e-230 766.2 3.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KEY70482.1 - 3.4e-16 58.7 0.4 2.1e-15 56.1 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KEY70482.1 - 0.00098 18.7 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KEY70482.1 - 0.2 11.4 3.2 3.4 7.5 1.1 3.4 2 1 0 2 2 2 0 Cell division protein FtsA ATP-grasp_4 PF13535.1 KEY70485.1 - 2.2e-22 79.6 0.0 3.1e-21 75.9 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KEY70485.1 - 2e-10 39.9 0.0 1.4e-06 27.2 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KEY70485.1 - 0.0007 19.0 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 KEY70485.1 - 0.0043 16.3 0.0 0.008 15.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Methyltransf_31 PF13847.1 KEY70486.1 - 1.1e-17 64.0 0.0 1.8e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY70486.1 - 1.8e-14 54.2 0.0 3.6e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY70486.1 - 3.1e-11 43.6 0.0 7.8e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY70486.1 - 1.2e-10 41.7 0.0 2.3e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY70486.1 - 1.2e-07 31.9 0.0 2.4e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY70486.1 - 1.1e-06 28.6 0.0 5.6e-06 26.3 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY70486.1 - 1.7e-06 27.8 0.0 3.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY70486.1 - 5.9e-06 25.7 0.0 1.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KEY70486.1 - 3.9e-05 22.8 0.0 6.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 KEY70486.1 - 0.00029 19.9 0.0 0.00049 19.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FAD_binding_8 PF08022.7 KEY70486.1 - 0.00048 19.9 0.0 0.059 13.2 0.0 2.4 2 0 0 2 2 2 1 FAD-binding domain Methyltransf_32 PF13679.1 KEY70486.1 - 0.0052 16.4 0.0 0.0097 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KEY70486.1 - 0.0075 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ferric_reduct PF01794.14 KEY70486.1 - 0.02 15.0 8.6 0.039 14.0 6.0 1.5 1 0 0 1 1 1 0 Ferric reductase like transmembrane component FmrO PF07091.6 KEY70486.1 - 0.02 13.9 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) FtsJ PF01728.14 KEY70486.1 - 0.032 14.2 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 KEY70486.1 - 0.064 12.4 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase TPMT PF05724.6 KEY70486.1 - 0.072 12.5 0.0 0.17 11.3 0.0 1.6 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_15 PF09445.5 KEY70486.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase RrnaAD PF00398.15 KEY70486.1 - 0.18 10.7 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF4293 PF14126.1 KEY70486.1 - 0.72 9.7 3.2 1.6 8.6 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) PTR2 PF00854.16 KEY70487.1 - 3.4e-13 49.1 4.9 6.5e-13 48.2 3.4 1.4 1 1 0 1 1 1 1 POT family Methyltransf_11 PF08241.7 KEY70488.1 - 2.7e-21 75.8 0.0 4e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY70488.1 - 9.2e-15 54.7 0.0 1.3e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY70488.1 - 8.6e-14 51.8 0.0 1.5e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY70488.1 - 8.1e-13 48.2 0.0 1.1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY70488.1 - 3.1e-10 40.3 0.0 5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY70488.1 - 6.6e-09 36.3 0.0 1.2e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY70488.1 - 2.7e-08 33.2 0.0 3.8e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.7 KEY70488.1 - 6.6e-07 28.4 0.0 9e-07 28.0 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_8 PF05148.10 KEY70488.1 - 1.2e-05 25.0 0.0 4e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_26 PF13659.1 KEY70488.1 - 8.1e-05 22.6 0.1 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KEY70488.1 - 0.00042 19.7 0.0 0.00059 19.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CheR PF01739.13 KEY70488.1 - 0.035 13.3 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_29 PF03141.11 KEY70488.1 - 0.045 12.0 0.0 0.051 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ank_2 PF12796.2 KEY70489.1 - 6e-77 254.0 0.2 2.4e-20 72.6 0.0 6.9 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 KEY70489.1 - 1e-76 249.1 0.2 8.7e-08 31.6 0.0 11.0 10 1 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.1 KEY70489.1 - 4.7e-55 178.0 4.3 2.1e-05 24.3 0.0 11.3 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.1 KEY70489.1 - 3.4e-52 173.9 11.9 2.3e-08 34.3 0.0 8.0 3 2 6 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY70489.1 - 1.4e-38 130.0 8.0 1.5e-09 37.8 0.0 6.9 3 2 2 6 6 6 6 Ankyrin repeats (many copies) NACHT PF05729.7 KEY70489.1 - 6.6e-07 29.1 0.1 1.9e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEY70489.1 - 1.4e-05 25.1 0.5 0.00019 21.4 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KEY70489.1 - 0.00051 20.1 0.0 0.0021 18.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 KEY70489.1 - 0.0046 15.9 0.9 0.17 10.8 0.0 2.3 1 1 1 2 2 2 1 KAP family P-loop domain ABC_tran PF00005.22 KEY70489.1 - 0.038 14.3 0.0 0.67 10.2 0.0 2.4 2 0 0 2 2 2 0 ABC transporter LIP PF03583.9 KEY70489.1 - 0.068 12.3 0.0 5.2 6.1 0.0 3.5 3 1 0 4 4 4 0 Secretory lipase AAA_10 PF12846.2 KEY70489.1 - 0.082 12.3 0.1 0.2 11.0 0.1 1.8 1 1 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 KEY70489.1 - 0.14 12.3 0.0 0.49 10.5 0.0 1.9 2 0 0 2 2 1 0 RNA helicase NB-ARC PF00931.17 KEY70489.1 - 0.24 10.2 0.0 0.53 9.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain CTP_transf_2 PF01467.21 KEY70492.1 - 2.1e-06 27.8 0.0 1.3e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 Cytidylyltransferase Mito_fiss_reg PF05308.6 KEY70493.1 - 0.3 10.3 4.7 0.36 10.1 3.3 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Rxt3 PF08642.5 KEY70494.1 - 6.3e-25 87.6 0.0 1.2e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 KEY70494.1 - 5.1e-05 23.1 0.0 0.0053 16.7 0.0 2.4 2 0 0 2 2 2 2 LCCL domain DUF1674 PF07896.7 KEY70495.1 - 7.1e-17 61.3 3.5 1e-16 60.8 2.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) HpaP PF09483.5 KEY70495.1 - 0.019 14.8 1.0 0.023 14.6 0.7 1.1 1 0 0 1 1 1 0 Type III secretion protein (HpaP) PHO4 PF01384.15 KEY70497.1 - 1.7e-115 385.1 7.8 2e-115 384.9 5.4 1.0 1 0 0 1 1 1 1 Phosphate transporter family Glyco_hydro_10 PF00331.15 KEY70498.1 - 1.6e-96 323.1 0.0 1.9e-96 322.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 KEY70498.1 - 4.4e-13 48.6 4.1 1e-12 47.4 2.9 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Sporozoite_P67 PF05642.6 KEY70498.1 - 0.19 9.5 5.1 0.28 8.9 3.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pox_A12 PF04651.8 KEY70498.1 - 6.9 6.7 8.8 12 5.9 6.1 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein Aminotran_5 PF00266.14 KEY70499.1 - 2.1e-15 56.3 0.0 2.7e-08 32.9 0.0 2.8 3 0 0 3 3 3 2 Aminotransferase class-V NYD-SP12_N PF15015.1 KEY70499.1 - 0.065 11.4 0.0 0.087 11.0 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal Pyrophosphatase PF00719.14 KEY70500.1 - 7.4e-36 122.9 0.0 9.7e-36 122.5 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF2769 PF10967.3 KEY70503.1 - 0.1 12.8 0.4 0.22 11.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2769) PADR1 PF08063.7 KEY70503.1 - 0.18 11.2 0.2 0.18 11.2 0.1 1.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain PT PF04886.7 KEY70505.1 - 0.016 14.4 12.2 0.016 14.4 8.5 6.5 7 0 0 7 7 7 0 PT repeat SKG6 PF08693.5 KEY70505.1 - 0.048 12.9 0.6 0.092 12.0 0.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Abhydrolase_2 PF02230.11 KEY70506.1 - 2.4e-26 92.5 0.0 5.3e-24 84.8 0.0 2.5 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KEY70506.1 - 1.9e-08 34.4 8.3 6.3e-08 32.7 5.8 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY70506.1 - 1.1e-06 28.5 0.1 2.3e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEY70506.1 - 1.8e-05 24.0 0.0 4.1e-05 22.9 0.0 1.6 2 1 0 2 2 2 1 Prolyl oligopeptidase family LIP PF03583.9 KEY70506.1 - 0.00021 20.6 0.0 0.00031 20.0 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase FSH1 PF03959.8 KEY70506.1 - 0.0042 16.5 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.6 KEY70506.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 KEY70506.1 - 0.17 11.1 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family GST_C PF00043.20 KEY70508.1 - 2.8e-06 27.2 0.0 4.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KEY70508.1 - 0.00079 19.2 0.1 0.0017 18.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEY70508.1 - 0.085 13.3 0.0 0.15 12.5 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Fungal_trans PF04082.13 KEY70509.1 - 3.4e-07 29.4 0.2 1e-06 27.8 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY70509.1 - 1e-06 28.5 8.4 2.3e-06 27.3 5.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 KEY70510.1 - 1.7e-24 86.3 0.1 2.2e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY70510.1 - 1.3e-15 57.8 0.2 2.1e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEY70510.1 - 2e-07 30.6 0.2 5.2e-06 26.0 0.1 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KEY70510.1 - 5.5e-06 25.6 0.1 8.5e-06 24.9 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 KEY70510.1 - 0.0033 17.3 0.6 0.0093 15.8 0.1 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 KEY70510.1 - 0.0035 16.1 0.2 0.015 13.9 0.1 2.1 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KEY70510.1 - 0.0074 16.2 0.5 0.016 15.0 0.3 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 KEY70510.1 - 0.023 14.9 0.1 0.05 13.9 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KEY70510.1 - 0.051 12.4 0.1 0.083 11.8 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Tombus_P19 PF03220.8 KEY70512.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Tombusvirus P19 core protein Acetyltransf_8 PF13523.1 KEY70513.1 - 8.7e-35 119.8 0.0 1.5e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF607 PF04678.8 KEY70514.1 - 3.8e-38 131.2 4.3 6.7e-38 130.3 1.0 2.5 2 1 0 2 2 2 1 Protein of unknown function, DUF607 GHMP_kinases_N PF00288.21 KEY70516.1 - 5.8e-10 39.0 2.7 1.7e-09 37.6 0.7 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain DUF647 PF04884.9 KEY70517.1 - 5.5e-90 300.9 3.3 7.3e-90 300.5 2.3 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis MerC PF03203.9 KEY70517.1 - 3.7 7.9 7.0 1.8 8.9 2.5 2.1 2 0 0 2 2 2 0 MerC mercury resistance protein Cyto_heme_lyase PF01265.12 KEY70518.1 - 1.6e-82 276.9 0.2 1.8e-82 276.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase CLN3 PF02487.12 KEY70520.1 - 8.6e-109 363.9 6.9 1.2e-100 337.2 0.2 2.0 1 1 1 2 2 2 2 CLN3 protein MFS_1 PF07690.11 KEY70520.1 - 1.4e-06 27.3 22.4 2.7e-06 26.3 3.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KEY70521.1 - 5.6e-07 28.4 0.1 8.1e-07 27.9 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY70521.1 - 0.025 14.4 7.1 0.053 13.4 4.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S28 PF05577.7 KEY70524.1 - 3e-51 174.3 0.1 1.1e-50 172.4 0.1 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 KEY70524.1 - 0.00031 20.7 0.1 0.00071 19.5 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lactamase_B_2 PF12706.2 KEY70526.1 - 1.9e-12 47.1 0.1 2.7e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KEY70526.1 - 7.3e-07 29.0 0.1 1.2e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Amidohydro_2 PF04909.9 KEY70526.1 - 0.034 13.6 0.1 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase DUF2328 PF10090.4 KEY70526.1 - 0.078 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2328) Glyco_transf_34 PF05637.7 KEY70528.1 - 4.7e-07 29.5 1.9 9.9e-07 28.5 1.3 1.5 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.11 KEY70528.1 - 1.5e-06 28.1 1.0 6.6e-06 26.0 0.1 2.0 1 1 1 2 2 2 1 Nucleotide-diphospho-sugar transferase DUF273 PF03314.9 KEY70528.1 - 0.0026 17.0 0.0 0.005 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Glyco_transf_8 PF01501.15 KEY70528.1 - 0.004 16.5 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 PNK3P PF08645.6 KEY70530.1 - 2e-53 180.1 0.0 3e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 KEY70530.1 - 4.2e-29 101.2 0.0 1.9e-28 99.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEY70530.1 - 0.0011 18.0 0.0 0.0035 16.4 0.0 1.7 1 1 1 2 2 2 1 Zeta toxin AAA_22 PF13401.1 KEY70530.1 - 0.0016 18.5 0.0 0.0038 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KEY70530.1 - 0.003 16.8 0.1 0.81 8.8 0.0 2.4 1 1 0 2 2 2 2 Chromatin associated protein KTI12 AAA_17 PF13207.1 KEY70530.1 - 0.0072 17.1 1.6 0.19 12.5 0.6 2.9 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEY70530.1 - 0.049 13.1 0.0 0.2 11.2 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain Med18 PF09637.5 KEY70531.1 - 1.8e-20 73.5 0.0 2.1e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Med18 protein DUF3129 PF11327.3 KEY70532.1 - 3e-54 183.6 12.3 3e-54 183.6 8.6 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3129) DUF1264 PF06884.6 KEY70534.1 - 9.8e-75 249.6 0.0 1.2e-74 249.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) DUF3292 PF11696.3 KEY70537.1 - 2e-225 749.5 0.0 2.6e-225 749.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) Lactamase_B PF00753.22 KEY70537.1 - 0.00013 21.7 0.1 0.00033 20.3 0.1 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Pex24p PF06398.6 KEY70537.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin LSM PF01423.17 KEY70539.1 - 1.7e-17 62.6 0.0 2e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF3806 PF12713.2 KEY70539.1 - 0.1 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3806) Glyco_tranf_2_2 PF10111.4 KEY70540.1 - 0.043 12.8 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 WSC PF01822.14 KEY70542.1 - 8.3e-72 237.1 60.0 2.2e-16 59.5 4.8 5.4 5 0 0 5 5 5 5 WSC domain PQQ_3 PF13570.1 KEY70542.1 - 7.7e-07 29.1 7.5 0.0032 17.6 0.1 4.2 3 0 0 3 3 3 2 PQQ-like domain PQQ_2 PF13360.1 KEY70542.1 - 7.3e-06 25.6 0.3 0.0039 16.6 0.0 3.4 3 0 0 3 3 3 1 PQQ-like domain PQQ PF01011.16 KEY70542.1 - 0.048 13.2 5.7 3.3 7.3 0.0 4.5 4 0 0 4 4 4 0 PQQ enzyme repeat Snf7 PF03357.16 KEY70544.1 - 2.1e-41 141.1 13.4 2.5e-41 140.8 9.3 1.1 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.7 KEY70544.1 - 9.2e-06 25.8 4.0 0.011 15.9 1.0 2.9 2 1 1 3 3 3 2 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 KEY70544.1 - 0.0018 17.5 2.4 0.022 13.9 0.3 2.0 1 1 1 2 2 2 1 Reovirus sigma C capsid protein Exonuc_VII_L PF02601.10 KEY70544.1 - 0.024 13.8 4.1 0.03 13.5 2.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prefoldin_2 PF01920.15 KEY70544.1 - 0.026 14.2 15.6 0.05 13.3 0.0 4.1 2 1 2 4 4 4 0 Prefoldin subunit Rogdi_lz PF10259.4 KEY70544.1 - 0.026 13.6 1.5 0.056 12.5 1.1 1.4 1 1 0 1 1 1 0 Rogdi leucine zipper containing protein DUF4407 PF14362.1 KEY70544.1 - 0.027 13.4 5.0 0.038 12.9 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6 PF04111.7 KEY70544.1 - 0.03 13.3 14.3 0.016 14.2 8.7 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 NuA4 PF09340.5 KEY70544.1 - 0.041 13.5 3.6 0.088 12.4 2.5 1.6 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 IncA PF04156.9 KEY70544.1 - 0.045 13.3 10.2 1.9 8.0 7.1 2.2 1 1 0 1 1 1 0 IncA protein FliD_C PF07195.7 KEY70544.1 - 0.056 12.7 8.2 0.072 12.3 0.0 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF1993 PF09351.5 KEY70544.1 - 0.073 12.9 2.9 0.13 12.2 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Allexi_40kDa PF05549.6 KEY70544.1 - 0.079 12.2 3.7 0.44 9.7 0.1 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF2205 PF10224.4 KEY70544.1 - 0.13 11.7 10.8 0.067 12.7 2.3 3.2 1 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) DUF848 PF05852.6 KEY70544.1 - 0.14 11.9 8.6 0.12 12.2 3.9 2.2 1 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Peptidase_M13 PF01431.16 KEY70544.1 - 0.17 11.0 2.1 0.24 10.5 1.5 1.2 1 0 0 1 1 1 0 Peptidase family M13 Sec34 PF04136.10 KEY70544.1 - 0.22 11.2 6.0 1.3 8.7 2.1 2.1 1 1 1 2 2 2 0 Sec34-like family NYD-SP28_assoc PF14775.1 KEY70544.1 - 0.22 11.2 8.2 1.1 8.9 1.1 3.4 2 1 1 3 3 3 0 Sperm tail C-terminal domain TBPIP PF07106.8 KEY70544.1 - 0.24 10.9 14.9 0.41 10.1 2.4 2.4 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 KEY70544.1 - 0.27 9.5 12.8 1.7 6.9 4.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) MitMem_reg PF13012.1 KEY70544.1 - 0.27 11.3 5.7 1.4 9.0 3.8 2.1 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Jnk-SapK_ap_N PF09744.4 KEY70544.1 - 0.28 11.1 14.4 4.3 7.3 7.7 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF972 PF06156.8 KEY70544.1 - 0.3 11.4 12.2 5.7 7.3 1.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 KEY70544.1 - 0.36 9.2 11.2 4.6 5.5 8.0 1.8 1 1 1 2 2 2 0 AAA domain CDC37_N PF03234.9 KEY70544.1 - 0.46 10.7 9.6 0.74 10.1 6.7 1.4 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding OmpH PF03938.9 KEY70544.1 - 0.52 10.2 17.7 0.19 11.6 8.1 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Mod_r PF07200.8 KEY70544.1 - 0.57 10.0 15.3 0.16 11.8 5.5 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Atg14 PF10186.4 KEY70544.1 - 0.57 9.0 9.5 0.91 8.4 6.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 EMP24_GP25L PF01105.19 KEY70544.1 - 0.63 9.7 4.8 21 4.7 2.6 2.4 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD SlyX PF04102.7 KEY70544.1 - 0.67 10.3 10.5 3.1 8.2 1.8 3.5 1 1 3 4 4 4 0 SlyX Spore_III_AF PF09581.5 KEY70544.1 - 0.76 9.6 7.8 1.1 9.0 5.4 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) FlaC_arch PF05377.6 KEY70544.1 - 0.82 9.6 6.7 26 4.8 2.1 3.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Mnd1 PF03962.10 KEY70544.1 - 1.1 8.8 13.4 4.5 6.8 9.2 1.9 1 1 0 1 1 1 0 Mnd1 family BLOC1_2 PF10046.4 KEY70544.1 - 1.2 9.3 11.9 2.3 8.3 3.4 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COG2 PF06148.6 KEY70544.1 - 1.6 8.5 10.0 4 7.3 3.4 2.9 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Strep_SA_rep PF06696.6 KEY70544.1 - 1.8 8.4 6.6 1.2 8.9 0.4 3.1 2 0 0 2 2 2 0 Streptococcal surface antigen repeat V_ATPase_I PF01496.14 KEY70544.1 - 1.9 6.2 8.6 4.1 5.1 6.0 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2730 PF10805.3 KEY70544.1 - 2.1 8.0 8.9 11 5.7 2.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) DUF2408 PF10303.4 KEY70544.1 - 2.8 8.0 9.6 9.1 6.4 6.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) FliD_N PF02465.13 KEY70544.1 - 3 8.2 10.0 18 5.7 3.2 2.7 1 1 2 3 3 2 0 Flagellar hook-associated protein 2 N-terminus DUF4140 PF13600.1 KEY70544.1 - 4.1 7.8 8.7 2.4 8.6 0.0 3.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4337 PF14235.1 KEY70544.1 - 4.8 6.9 11.0 0.94 9.2 4.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) WD40 PF00400.27 KEY70545.1 - 9e-36 120.4 3.3 1.3e-06 28.0 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 KEY70545.1 - 2.6e-14 52.6 0.4 6.7e-14 51.3 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEY70545.1 - 5.1e-06 26.0 0.4 3.4e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 KEY70545.1 - 0.00078 17.6 0.1 0.4 8.7 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 MgtE_N PF03448.12 KEY70545.1 - 0.002 18.3 0.0 0.0052 17.0 0.0 1.6 1 0 0 1 1 1 1 MgtE intracellular N domain BBS2_Mid PF14783.1 KEY70545.1 - 0.012 15.3 0.0 0.5 10.1 0.0 3.1 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region SmpA_OmlA PF04355.8 KEY70545.1 - 0.013 15.1 1.5 0.18 11.4 0.1 3.0 3 0 0 3 3 3 0 SmpA / OmlA family PH_10 PF15411.1 KEY70546.1 - 2.5e-44 150.1 0.2 5e-44 149.2 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 KEY70546.1 - 2.8e-33 113.8 0.0 5.6e-33 112.8 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.15 KEY70546.1 - 1.2e-28 100.2 0.1 1.9e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 KEY70546.1 - 2.2e-08 33.6 0.0 5.6e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 KEY70546.1 - 0.01 16.0 0.2 0.022 14.9 0.2 1.5 1 0 0 1 1 1 0 PH domain MFS_1 PF07690.11 KEY70547.1 - 0.012 14.3 0.1 0.012 14.3 0.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF3481 PF11980.3 KEY70547.1 - 0.025 14.3 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) PepSY_TM_2 PF13703.1 KEY70547.1 - 0.058 13.5 2.9 0.12 12.5 2.0 1.5 1 1 0 1 1 1 0 PepSY-associated TM helix CopD PF05425.8 KEY70547.1 - 0.11 12.6 0.3 0.14 12.4 0.2 1.1 1 0 0 1 1 1 0 Copper resistance protein D OPT PF03169.10 KEY70549.1 - 3.3e-169 564.2 45.9 3.8e-169 564.0 31.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Fungal_trans_2 PF11951.3 KEY70550.1 - 0.00084 18.0 0.7 0.0035 16.0 0.5 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Rtt106 PF08512.7 KEY70551.1 - 1.2e-22 79.6 0.0 2.4e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Nop14 PF04147.7 KEY70551.1 - 2.5 5.9 36.0 3.4 5.4 25.0 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 KEY70551.1 - 4.1 6.5 23.5 6.4 5.9 16.3 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Vfa1 PF08432.5 KEY70552.1 - 4.9e-53 179.8 33.8 5.5e-53 179.7 23.4 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Astro_capsid PF03115.9 KEY70552.1 - 0.42 8.8 9.0 0.45 8.7 6.2 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Ycf1 PF05758.7 KEY70552.1 - 0.7 7.5 19.9 0.78 7.3 13.8 1.0 1 0 0 1 1 1 0 Ycf1 Nop14 PF04147.7 KEY70552.1 - 0.76 7.6 31.4 0.89 7.3 21.8 1.0 1 0 0 1 1 1 0 Nop14-like family UPF0560 PF10577.4 KEY70552.1 - 1.6 6.8 11.9 1.9 6.6 8.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Raftlin PF15250.1 KEY70552.1 - 2.5 6.5 12.5 3 6.2 8.7 1.1 1 0 0 1 1 1 0 Raftlin Zip PF02535.17 KEY70552.1 - 2.6 6.9 4.5 2.9 6.8 3.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 KEY70552.1 - 3.2 5.6 30.2 4.1 5.3 21.0 1.0 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpb1_5 PF04998.12 KEY70552.1 - 6 6.0 7.5 7.2 5.7 5.2 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Hid1 PF12722.2 KEY70552.1 - 6.9 4.2 12.6 7.5 4.0 8.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF262 PF03235.9 KEY70552.1 - 8.7 6.2 13.0 11 5.9 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 TP53IP5 PF15331.1 KEY70552.1 - 9 6.1 15.3 12 5.7 10.6 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Peptidase_M28 PF04389.12 KEY70553.1 - 5.1e-30 104.5 0.0 7.7e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KEY70553.1 - 3e-13 49.3 0.0 5.7e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 KEY70553.1 - 8.8e-06 25.3 0.0 1.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 zf-C2H2 PF00096.21 KEY70556.1 - 0.0012 19.0 24.7 0.0032 17.7 0.7 5.3 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KEY70556.1 - 0.0022 18.1 0.4 0.0022 18.1 0.3 4.6 5 0 0 5 5 5 1 Zinc-finger double domain zf-CHCC PF10276.4 KEY70556.1 - 0.003 17.3 3.8 0.36 10.7 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger domain zf-C2H2_4 PF13894.1 KEY70556.1 - 0.012 15.9 1.2 0.012 15.9 0.8 5.7 5 1 0 5 5 5 0 C2H2-type zinc finger DSPc PF00782.15 KEY70557.1 - 2.4e-16 59.5 0.0 1e-08 34.8 0.0 3.2 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEY70557.1 - 0.0031 16.8 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 KEY70557.1 - 0.034 13.0 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase zf-DNA_Pol PF08996.5 KEY70557.1 - 0.11 11.8 0.1 0.34 10.2 0.0 1.7 1 1 0 1 1 1 0 DNA Polymerase alpha zinc finger Condensation PF00668.15 KEY70558.1 - 2e-75 253.4 0.0 1.2e-25 89.9 0.0 3.5 3 0 0 3 3 3 3 Condensation domain AMP-binding PF00501.23 KEY70558.1 - 1.8e-30 105.6 0.0 2.8e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 KEY70558.1 - 0.0045 17.2 0.2 0.29 11.4 0.0 3.5 3 0 0 3 3 3 1 Phosphopantetheine attachment site DUF4118 PF13493.1 KEY70558.1 - 0.062 13.5 0.7 4.9 7.4 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4118) G6PD_bact PF10786.4 KEY70558.1 - 0.78 9.1 0.0 3.6 6.9 0.0 1.9 2 0 0 2 2 2 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) SAPS PF04499.10 KEY70559.1 - 2e-165 551.0 4.9 4.7e-162 539.9 0.0 3.8 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein Peptidase_S8 PF00082.17 KEY70560.1 - 1.5e-49 168.6 6.1 2.3e-49 168.0 4.2 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KEY70560.1 - 1.1e-11 45.1 0.1 1.7e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 GCFC PF07842.7 KEY70561.1 - 5.1e-67 226.1 1.3 8.8e-67 225.3 0.9 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 KEY70561.1 - 2.1e-15 56.1 2.9 2.1e-15 56.1 2.0 2.2 2 0 0 2 2 2 1 G-patch domain TIP_N PF12457.3 KEY70561.1 - 5.1e-10 39.3 13.6 5.1e-10 39.3 9.4 3.3 2 1 1 3 3 3 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.2 KEY70561.1 - 1.8e-08 34.1 3.9 1.9e-08 34.0 1.0 2.4 2 0 0 2 2 2 1 DExH-box splicing factor binding site HEAT_2 PF13646.1 KEY70562.1 - 2.1e-07 31.1 1.8 0.42 10.9 0.2 4.5 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.17 KEY70562.1 - 0.00022 21.0 1.1 0.74 10.0 0.1 4.9 7 0 0 7 7 7 1 HEAT repeat CLASP_N PF12348.3 KEY70562.1 - 0.00096 18.5 0.0 0.0049 16.2 0.0 2.0 2 0 0 2 2 2 1 CLASP N terminal TPR_MLP1_2 PF07926.7 KEY70562.1 - 0.016 14.9 1.0 0.016 14.9 0.7 2.3 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 KEY70562.1 - 0.047 12.7 12.4 0.013 14.6 6.1 1.8 3 0 0 3 3 3 0 Autophagy protein Apg6 MAP65_ASE1 PF03999.7 KEY70562.1 - 0.11 11.1 5.1 0.2 10.2 3.5 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF972 PF06156.8 KEY70562.1 - 0.41 11.0 5.5 2.6 8.4 3.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.17 KEY70562.1 - 5.2 7.1 11.4 1.2 9.1 4.9 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain WI12 PF07107.6 KEY70563.1 - 0.023 14.5 0.1 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Wound-induced protein WI12 DUF3429 PF11911.3 KEY70564.1 - 1.5e-40 138.4 6.4 1.9e-40 138.0 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF1510 PF07423.6 KEY70564.1 - 0.0065 15.8 23.3 0.0098 15.2 16.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 KEY70564.1 - 0.014 15.3 2.2 0.024 14.5 1.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ycf1 PF05758.7 KEY70564.1 - 1 7.0 13.6 1.3 6.6 9.5 1.1 1 0 0 1 1 1 0 Ycf1 GAGA_bind PF06217.7 KEY70564.1 - 5.8 6.7 16.1 8.8 6.1 11.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family NARP1 PF12569.3 KEY70564.1 - 6.7 5.3 25.9 9.4 4.8 17.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1162 PF06650.7 KEY70565.1 - 2.2e-89 299.3 0.1 8.4e-87 290.8 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 KEY70565.1 - 2.2e-41 140.0 0.0 6.4e-41 138.5 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 KEY70565.1 - 4.7e-06 26.6 0.3 6.8e-05 22.9 0.0 2.6 2 0 0 2 2 2 1 ATG C terminal domain Rib_recp_KP_reg PF05104.7 KEY70566.1 - 2.1 8.8 7.4 2.5 8.6 5.1 1.1 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Nucleos_tra2_C PF07662.8 KEY70567.1 - 3e-68 229.4 1.0 3e-68 229.4 0.7 2.5 2 1 0 2 2 2 2 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KEY70567.1 - 1.3e-22 79.8 2.1 1.3e-22 79.8 1.4 3.6 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Aminotran_3 PF00202.16 KEY70569.1 - 1.8e-84 283.4 0.1 2.1e-84 283.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Ceramidase PF05875.7 KEY70570.1 - 6.3e-74 248.4 0.3 7.5e-74 248.1 0.2 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.6 KEY70570.1 - 1.1 9.1 4.1 3.1 7.6 2.8 1.8 1 0 0 1 1 1 0 Trp-operon Leader Peptide PLA2_B PF01735.13 KEY70571.1 - 6.8e-17 60.8 0.1 5.1e-11 41.4 0.1 3.1 3 0 0 3 3 3 3 Lysophospholipase catalytic domain ACPS PF01648.15 KEY70571.1 - 0.00012 21.8 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF4586 PF15239.1 KEY70573.1 - 0.11 12.0 0.5 0.13 11.8 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4586) DUF2985 PF11204.3 KEY70575.1 - 1.7e-28 98.1 5.8 3.6e-28 97.1 4.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Pec_lyase_C PF00544.14 KEY70576.1 - 0.004 16.6 4.5 0.0091 15.4 3.1 1.7 1 1 0 1 1 1 1 Pectate lyase NmrA PF05368.8 KEY70577.1 - 5.3e-13 48.7 0.0 8.4e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY70577.1 - 2.4e-06 27.6 1.0 5.1e-06 26.6 0.7 1.6 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KEY70577.1 - 0.0033 17.7 0.0 0.0079 16.4 0.0 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Fungal_trans PF04082.13 KEY70579.1 - 1.3e-14 53.7 0.0 1.9e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY70579.1 - 5.3e-11 42.2 9.4 9e-11 41.5 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox PF00070.22 KEY70580.1 - 4.2e-15 55.8 0.1 5.8e-12 45.8 0.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEY70580.1 - 1.3e-09 38.2 0.0 4.7e-09 36.4 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEY70580.1 - 3.5e-08 32.7 5.4 0.15 10.9 0.3 4.1 3 1 1 4 4 4 4 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEY70580.1 - 6e-08 32.9 0.6 0.00036 20.6 0.1 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEY70580.1 - 1.7e-06 27.1 0.0 5.8e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KEY70580.1 - 0.0002 21.1 3.4 2.6 7.7 0.0 4.2 3 1 1 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KEY70580.1 - 0.0011 17.9 0.1 0.3 9.9 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein TrkA_N PF02254.13 KEY70580.1 - 0.0061 16.5 0.0 0.86 9.6 0.0 2.7 2 0 0 2 2 2 1 TrkA-N domain ThiF PF00899.16 KEY70580.1 - 0.029 14.1 0.5 4.8 7.0 0.0 3.1 3 0 0 3 3 3 0 ThiF family HI0933_like PF03486.9 KEY70580.1 - 1.5 7.2 7.6 2.6 6.4 0.0 3.4 3 1 1 4 4 4 0 HI0933-like protein Dna2 PF08696.6 KEY70581.1 - 0.085 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 DNA replication factor Dna2 Aminotran_3 PF00202.16 KEY70582.1 - 1.4e-52 178.6 0.0 7.1e-52 176.3 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-III Cupin_3 PF05899.7 KEY70582.1 - 0.0063 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) DAO PF01266.19 KEY70583.1 - 3.7e-45 154.3 0.1 4.7e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY70583.1 - 0.0088 16.0 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain zf-HC5HC2H_2 PF13832.1 KEY70584.1 - 2.7e-20 72.4 1.4 2.7e-20 72.4 1.0 4.2 3 1 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KEY70584.1 - 1.1e-16 60.7 2.8 1.1e-16 60.7 1.9 4.9 5 0 0 5 5 5 1 PHD-like zinc-binding domain BAH PF01426.13 KEY70584.1 - 6.7e-16 58.1 0.0 1.3e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 KEY70584.1 - 8.5e-12 44.5 53.8 9.6e-07 28.3 5.0 6.2 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.1 KEY70584.1 - 3.7e-10 38.9 4.1 3.7e-10 38.9 2.8 5.5 6 0 0 6 6 6 2 PHD-finger Myb_DNA-binding PF00249.26 KEY70584.1 - 2.2e-05 24.4 0.0 8.3e-05 22.5 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Prok-RING_1 PF14446.1 KEY70584.1 - 9.7e-05 22.0 41.8 0.0027 17.4 5.3 4.5 4 0 0 4 4 4 3 Prokaryotic RING finger family 1 C1_1 PF00130.17 KEY70584.1 - 0.0085 15.8 1.2 0.0085 15.8 0.9 5.6 6 1 0 6 6 6 2 Phorbol esters/diacylglycerol binding domain (C1 domain) TrkA_C PF02080.16 KEY70584.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-C domain Pkinase PF00069.20 KEY70585.1 - 1.2e-12 47.6 0.0 4e-12 45.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY70585.1 - 0.001 18.1 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KEY70586.1 - 1.5e-13 50.5 0.0 1.6e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY70586.1 - 4e-06 26.1 0.1 3.1e-05 23.1 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY70586.1 - 0.17 10.7 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Glyco_hydro_38 PF01074.17 KEY70587.1 - 2.7e-90 302.3 0.1 4.1e-90 301.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KEY70587.1 - 6.2e-65 219.7 1.0 3.8e-64 217.1 0.7 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KEY70587.1 - 6.8e-24 83.8 0.0 1.5e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain MutS_V PF00488.16 KEY70588.1 - 1.5e-81 273.2 0.0 2.3e-81 272.6 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KEY70588.1 - 6.4e-45 153.4 0.0 1.6e-44 152.1 0.0 1.7 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KEY70588.1 - 8.5e-19 67.6 0.0 3.1e-18 65.8 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 KEY70588.1 - 1.3e-09 38.1 0.0 4.4e-09 36.5 0.0 1.9 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KEY70588.1 - 2.8e-05 24.2 0.0 6.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 KEY70588.1 - 0.039 13.4 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KEY70588.1 - 0.2 11.9 0.0 0.57 10.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ribosomal_L10 PF00466.15 KEY70589.1 - 1e-23 83.1 0.1 2.1e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 KEY70589.1 - 5.2e-22 78.0 5.6 5.2e-22 78.0 3.9 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein WD40 PF00400.27 KEY70590.1 - 0.00019 21.1 0.1 2.1 8.3 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat PQQ_2 PF13360.1 KEY70590.1 - 0.002 17.6 0.1 1.7 8.0 0.0 3.4 4 0 0 4 4 4 1 PQQ-like domain Ribosomal_L27 PF01016.14 KEY70590.1 - 0.13 12.0 3.6 0.24 11.2 1.7 2.0 2 0 0 2 2 2 0 Ribosomal L27 protein DnaJ PF00226.26 KEY70591.1 - 4e-28 96.9 1.9 7.5e-28 96.0 1.3 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KEY70591.1 - 5.6e-21 74.2 0.1 8.4e-18 64.0 0.0 2.8 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KEY70591.1 - 3.3e-14 52.6 17.8 5.5e-14 51.9 12.4 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KEY70591.1 - 0.025 14.2 9.1 0.062 12.9 1.3 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc-ribbons_6 PF07191.7 KEY70591.1 - 0.12 12.1 6.0 2.8 7.7 0.9 2.4 2 0 0 2 2 2 0 zinc-ribbons DUF2614 PF11023.3 KEY70591.1 - 0.17 11.6 5.4 1.5 8.6 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) zf-RING_3 PF14369.1 KEY70591.1 - 0.19 11.7 2.4 27 4.8 0.1 3.3 3 0 0 3 3 3 0 zinc-finger Lar_restr_allev PF14354.1 KEY70591.1 - 4.6 7.6 6.2 22 5.4 4.3 2.2 1 1 0 1 1 1 0 Restriction alleviation protein Lar DUF3425 PF11905.3 KEY70592.1 - 5.9e-21 74.7 2.0 1.1e-20 73.8 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KEY70592.1 - 0.0015 18.4 4.1 0.0037 17.1 2.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KEY70592.1 - 0.014 15.2 4.9 0.027 14.2 3.4 1.5 1 0 0 1 1 1 0 Basic region leucine zipper CAP_GLY PF01302.20 KEY70593.1 - 3.8e-16 58.5 1.1 9.3e-16 57.2 0.7 1.7 1 0 0 1 1 1 1 CAP-Gly domain Spc7 PF08317.6 KEY70593.1 - 0.0034 16.0 20.5 0.39 9.3 5.0 3.2 3 0 0 3 3 3 3 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 KEY70593.1 - 0.016 15.0 3.5 0.99 9.2 0.1 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pyr_redox_2 PF07992.9 KEY70593.1 - 0.034 14.0 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AAA_13 PF13166.1 KEY70593.1 - 0.21 10.0 18.4 0.004 15.7 5.5 2.3 1 1 0 2 2 2 0 AAA domain Reo_sigmaC PF04582.7 KEY70593.1 - 0.25 10.4 9.7 0.8 8.8 1.0 3.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 KEY70593.1 - 0.26 11.5 8.3 9.6 6.5 0.1 3.8 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.4 KEY70593.1 - 0.28 11.3 11.5 2.9 8.0 0.0 3.5 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.7 KEY70593.1 - 0.86 9.3 22.6 0.073 12.8 4.8 3.3 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 KEY70593.1 - 0.92 8.9 15.5 2.2 7.7 0.1 3.6 4 0 0 4 4 4 0 Phage minor structural protein GP20 Exonuc_VII_S PF02609.11 KEY70593.1 - 0.97 9.2 8.7 0.45 10.3 3.4 2.5 2 0 0 2 2 2 0 Exonuclease VII small subunit Glutaredoxin2_C PF04399.8 KEY70593.1 - 1.6 8.3 5.2 13 5.3 0.0 2.9 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain TBPIP PF07106.8 KEY70593.1 - 2.5 7.6 17.5 5.8 6.4 2.3 3.4 3 1 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF16 PF01519.11 KEY70593.1 - 4.8 7.4 7.2 60 3.9 0.0 3.7 3 1 0 3 3 3 0 Protein of unknown function DUF16 CENP-F_leu_zip PF10473.4 KEY70593.1 - 5.7 6.8 33.9 1.3 8.8 6.5 4.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.5 KEY70593.1 - 7.5 6.6 16.2 15 5.7 1.5 3.9 1 1 3 5 5 5 0 Fibrinogen alpha/beta chain family HEAT_2 PF13646.1 KEY70594.1 - 0.0039 17.4 0.1 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 HEAT repeats Nop14 PF04147.7 KEY70595.1 - 3.6e-253 842.3 31.4 4.4e-253 842.0 21.8 1.0 1 0 0 1 1 1 1 Nop14-like family DUF4187 PF13821.1 KEY70596.1 - 8.3e-18 63.7 1.8 4.5e-17 61.3 1.3 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 KEY70596.1 - 4.3e-09 36.0 4.3 8.8e-09 35.0 3.0 1.6 1 0 0 1 1 1 1 G-patch domain BTV_NS2 PF04514.7 KEY70596.1 - 4.7 5.9 23.1 0.45 9.3 11.5 2.0 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Myosin_tail_1 PF01576.14 KEY70597.1 - 0.0014 16.4 14.3 0.0019 16.0 9.9 1.1 1 0 0 1 1 1 1 Myosin tail ATG16 PF08614.6 KEY70597.1 - 0.1 12.3 16.5 0.026 14.3 8.8 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF904 PF06005.7 KEY70597.1 - 0.46 10.8 13.1 3.5 7.9 2.7 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF904) HSP70 PF00012.15 KEY70598.1 - 2.1e-06 26.0 0.0 0.0016 16.4 0.0 2.5 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 KEY70598.1 - 0.06 11.9 0.1 0.5 8.8 0.1 2.2 2 0 0 2 2 2 0 MreB/Mbl protein MFS_1 PF07690.11 KEY70599.1 - 9.6e-25 87.0 43.2 1.6e-19 69.8 20.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.13 KEY70599.1 - 0.11 10.9 8.2 0.033 12.7 1.9 2.1 2 0 0 2 2 2 0 Reduced folate carrier TRI12 PF06609.8 KEY70599.1 - 0.12 10.5 15.4 0.008 14.4 1.5 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) HlyIII PF03006.15 KEY70600.1 - 1.3e-50 171.8 12.8 1.7e-50 171.4 8.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related DnaJ PF00226.26 KEY70601.1 - 2.8e-12 46.1 0.2 5.3e-12 45.2 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1509 PF07420.6 KEY70602.1 - 0.47 9.6 10.2 0.69 9.1 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Transformer PF06495.6 KEY70602.1 - 0.71 9.7 14.4 1.6 8.5 10.0 1.5 1 0 0 1 1 1 0 Fruit fly transformer protein Cgr1 PF03879.9 KEY70604.1 - 5.8e-36 122.9 31.9 6.9e-36 122.7 22.1 1.0 1 0 0 1 1 1 1 Cgr1 family PRP1_N PF06424.7 KEY70604.1 - 0.0071 16.6 12.8 0.009 16.3 8.9 1.1 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal SprA-related PF12118.3 KEY70604.1 - 1.2 8.3 11.7 1.4 8.2 8.1 1.1 1 0 0 1 1 1 0 SprA-related family Mnd1 PF03962.10 KEY70604.1 - 3.3 7.3 14.5 3.9 7.0 10.1 1.1 1 0 0 1 1 1 0 Mnd1 family SPATIAL PF15256.1 KEY70604.1 - 4.1 7.4 8.5 4.5 7.2 5.9 1.1 1 0 0 1 1 1 0 SPATIAL DDHD PF02862.12 KEY70604.1 - 4.3 7.0 8.9 4.5 6.9 6.2 1.1 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 KEY70604.1 - 4.6 7.0 12.8 4.9 6.9 8.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Metal_resist PF13801.1 KEY70604.1 - 9.7 6.1 10.0 11 6.0 6.9 1.2 1 0 0 1 1 1 0 Heavy-metal resistance Fib_alpha PF08702.5 KEY70605.1 - 0.003 17.6 2.9 0.036 14.2 1.1 2.3 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family Spc7 PF08317.6 KEY70605.1 - 0.042 12.5 4.2 0.058 12.0 2.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein FlaC_arch PF05377.6 KEY70605.1 - 0.11 12.4 0.4 0.59 10.0 0.0 2.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF948 PF06103.6 KEY70605.1 - 0.15 11.9 2.5 0.21 11.4 0.1 2.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.10 KEY70605.1 - 0.57 9.7 4.2 3.6 7.1 0.2 2.8 2 1 1 3 3 3 0 Septum formation initiator Rho_Binding PF08912.6 KEY70605.1 - 0.95 9.8 3.4 39 4.6 1.4 2.4 1 1 1 2 2 2 0 Rho Binding DUF2205 PF10224.4 KEY70605.1 - 1.5 8.4 5.0 2.7 7.6 0.1 3.1 1 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) DUF607 PF04678.8 KEY70605.1 - 1.9 8.3 6.1 1.2 8.9 1.7 2.3 2 1 0 2 2 2 0 Protein of unknown function, DUF607 DUF3818 PF12825.2 KEY70606.1 - 4.9e-135 449.6 7.0 7e-135 449.0 4.9 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KEY70606.1 - 1.1e-42 144.9 0.3 2.3e-42 143.8 0.2 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.19 KEY70606.1 - 4.6e-15 55.4 0.0 1.3e-13 50.7 0.0 3.1 2 1 0 2 2 2 1 PX domain UPF0227 PF05728.7 KEY70606.1 - 0.25 11.0 1.7 0.37 10.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) AP_endonuc_2 PF01261.19 KEY70607.1 - 5e-26 91.3 0.0 7.5e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel zf-GRF PF06839.7 KEY70608.1 - 6e-08 32.4 7.3 1.1e-07 31.6 5.0 1.5 1 0 0 1 1 1 1 GRF zinc finger ADK PF00406.17 KEY70609.1 - 2.6e-44 150.7 0.0 3.5e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.1 KEY70609.1 - 3.3e-08 33.4 0.0 2e-07 30.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEY70609.1 - 3.4e-08 33.8 0.0 5.4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEY70609.1 - 1.8e-06 28.7 0.0 2.9e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KEY70609.1 - 9.2e-05 21.8 0.1 0.28 10.5 0.0 2.3 2 0 0 2 2 2 2 Thymidylate kinase PCI PF01399.22 KEY70610.1 - 4e-19 68.8 0.1 1.6e-18 66.9 0.0 2.1 2 0 0 2 2 2 1 PCI domain K_channel_TID PF07941.6 KEY70610.1 - 0.12 12.5 3.1 0.25 11.5 2.1 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Pkinase PF00069.20 KEY70611.1 - 9.9e-80 267.4 0.0 1.4e-79 266.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY70611.1 - 2.6e-39 134.8 0.0 3.7e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KEY70611.1 - 1.4e-16 60.3 0.4 2.6e-16 59.4 0.3 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KEY70611.1 - 2.2e-11 43.2 0.0 5e-10 38.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 KEY70611.1 - 0.0056 15.5 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 KEY70611.1 - 0.086 12.1 0.2 0.34 10.2 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.9 KEY70611.1 - 0.087 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ArfGap PF01412.13 KEY70612.1 - 1.2e-33 115.4 1.5 2.1e-33 114.5 0.0 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 KEY70612.1 - 1.5e-12 47.6 0.0 3.7e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 PH domain Membr_traf_MHD PF10540.4 KEY70613.1 - 1.8e-20 73.1 0.1 4.5e-20 71.8 0.0 1.7 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 KEY70613.1 - 1.4e-17 63.2 0.0 3.3e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.6 KEY70613.1 - 7e-05 21.3 0.2 0.00014 20.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF810) HAMP PF00672.20 KEY70614.1 - 1.1e-46 156.8 22.9 3.5e-09 36.7 0.1 7.5 7 0 0 7 7 7 6 HAMP domain HATPase_c PF02518.21 KEY70614.1 - 9.2e-30 102.6 0.2 3.9e-29 100.6 0.2 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KEY70614.1 - 1.3e-28 99.1 0.5 2.6e-25 88.6 0.2 2.9 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 KEY70614.1 - 2.3e-18 65.9 0.5 2.3e-18 65.9 0.4 4.6 5 0 0 5 5 5 1 His Kinase A (phospho-acceptor) domain NAAA-beta PF15508.1 KEY70614.1 - 0.052 13.8 3.3 6.4 7.1 0.1 5.3 3 2 2 5 5 5 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF883 PF05957.8 KEY70614.1 - 0.3 11.4 20.0 1.2 9.5 0.3 6.5 4 3 1 5 5 5 0 Bacterial protein of unknown function (DUF883) PMC2NT PF08066.7 KEY70614.1 - 0.31 11.3 9.1 7.2 6.9 0.3 4.9 4 0 0 4 4 4 0 PMC2NT (NUC016) domain DUF2365 PF10157.4 KEY70614.1 - 0.98 9.2 14.3 4.6 7.1 0.0 6.1 5 2 1 7 7 7 0 Uncharacterized conserved protein (DUF2365) Pox_A_type_inc PF04508.7 KEY70614.1 - 1.8 8.5 7.1 2.9 7.8 0.2 4.9 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat Baculo_PEP_C PF04513.7 KEY70615.1 - 0.027 14.2 0.1 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HMG_box PF00505.14 KEY70616.1 - 5.4e-13 48.9 3.0 9.2e-10 38.6 0.8 2.8 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 KEY70616.1 - 4.4e-11 42.9 2.2 5.5e-09 36.2 1.5 2.8 1 1 0 1 1 1 1 HMG-box domain SAM_1 PF00536.25 KEY70616.1 - 1.1e-10 41.4 0.0 1.9e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KEY70616.1 - 1.2e-07 31.4 0.0 2.7e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Cnd2 PF05786.9 KEY70617.1 - 4.1e-214 713.2 0.2 5.2e-214 712.8 0.1 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 Na_Ca_ex PF01699.19 KEY70618.1 - 1.2e-47 161.0 32.7 1.5e-25 89.3 4.2 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Pex14_N PF04695.8 KEY70618.1 - 0.16 12.0 0.1 0.77 9.7 0.0 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PMM PF03332.8 KEY70619.1 - 8.3e-102 339.4 0.1 9.6e-102 339.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 KEY70619.1 - 4.2e-05 23.2 0.0 0.00026 20.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 KEY70619.1 - 0.025 13.6 0.0 0.034 13.2 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein CTV_P13 PF06922.6 KEY70619.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Citrus tristeza virus P13 protein WW PF00397.21 KEY70620.1 - 9.6e-09 34.9 0.1 3.5e-08 33.1 0.0 2.1 1 0 0 1 1 1 1 WW domain PhoD PF09423.5 KEY70620.1 - 0.00017 20.2 0.4 0.00026 19.6 0.3 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase MutS_V PF00488.16 KEY70621.1 - 6.7e-82 274.4 0.0 1.3e-81 273.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KEY70621.1 - 2e-38 132.2 2.9 4e-38 131.2 2.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KEY70621.1 - 5.4e-28 97.2 0.0 1.3e-27 96.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KEY70621.1 - 1.4e-09 38.1 0.2 1.3e-08 35.0 0.0 2.5 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 KEY70621.1 - 1.1e-08 35.1 0.0 3.2e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_28 PF13521.1 KEY70621.1 - 0.02 14.8 4.3 0.27 11.1 0.1 3.4 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 KEY70621.1 - 0.15 11.6 0.0 0.46 10.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-C2H2_2 PF12756.2 KEY70622.1 - 0.035 14.2 0.1 0.066 13.3 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Prenyltrans PF00432.16 KEY70623.1 - 1.3e-64 213.3 6.7 9.7e-13 47.4 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KEY70623.1 - 1.2e-40 138.4 0.0 1.2e-16 61.1 0.0 3.9 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KEY70623.1 - 3.2e-14 52.8 0.0 1.2e-05 25.2 0.0 3.3 1 1 2 3 3 3 2 Prenyltransferase-like DUF630 PF04783.7 KEY70623.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF630) RhoGAP PF00620.22 KEY70624.1 - 5.3e-29 100.7 0.0 9.8e-29 99.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain RRS1 PF04939.7 KEY70625.1 - 7.8e-58 194.5 5.5 1e-57 194.1 3.8 1.2 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DAP3 PF10236.4 KEY70626.1 - 2.9e-82 276.0 0.0 3.7e-82 275.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.1 KEY70626.1 - 0.074 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEY70626.1 - 0.12 11.9 0.1 0.51 9.8 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain MCM PF00493.18 KEY70627.1 - 2.7e-135 450.4 0.1 8.2e-135 448.8 0.0 1.7 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 KEY70627.1 - 9e-25 87.5 0.8 1.9e-24 86.4 0.1 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KEY70627.1 - 3.8e-08 32.7 0.1 1e-05 24.8 0.0 2.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KEY70627.1 - 1.5e-05 24.7 0.0 6.5e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 KEY70627.1 - 0.00038 20.7 0.4 0.0015 18.9 0.1 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KEY70627.1 - 0.02 14.5 0.0 0.075 12.6 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KEY70627.1 - 0.11 11.9 0.1 0.73 9.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 KEY70628.1 - 3.9e-58 195.3 0.0 2.2e-43 147.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 KEY70628.1 - 1.1e-25 89.5 0.5 2.6e-25 88.2 0.3 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 KEY70628.1 - 2.2e-13 50.6 3.7 1.9e-08 34.4 0.1 4.0 2 1 0 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 KEY70628.1 - 1.9e-08 34.2 0.0 0.00013 21.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KEY70628.1 - 5.7e-08 33.6 0.0 0.0031 18.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 KEY70628.1 - 6.2e-08 32.4 0.7 5.7e-05 22.8 0.0 3.7 3 1 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 KEY70628.1 - 1.3e-07 31.8 1.2 0.0044 17.1 0.0 4.0 3 2 0 3 3 2 2 AAA domain AAA_18 PF13238.1 KEY70628.1 - 2.1e-07 31.3 0.0 0.00016 21.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 KEY70628.1 - 4.4e-07 29.9 0.0 0.0086 15.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KEY70628.1 - 3e-06 27.1 0.0 0.061 13.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KEY70628.1 - 5.2e-06 26.2 0.2 0.02 14.6 0.0 3.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KEY70628.1 - 5.8e-06 25.5 0.0 0.012 14.7 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KEY70628.1 - 5.9e-06 25.9 0.1 0.027 14.2 0.0 3.6 3 0 0 3 3 2 1 Part of AAA domain Sigma54_activ_2 PF14532.1 KEY70628.1 - 8.1e-06 25.9 0.0 0.0014 18.7 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 KEY70628.1 - 1.4e-05 24.6 0.2 0.021 14.2 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 KEY70628.1 - 3.6e-05 22.9 0.0 0.05 12.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.1 KEY70628.1 - 5.4e-05 23.2 0.0 0.062 13.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain UPF0079 PF02367.12 KEY70628.1 - 0.00018 21.1 0.1 0.0031 17.1 0.0 2.5 3 0 0 3 3 2 1 Uncharacterised P-loop hydrolase UPF0079 SKI PF01202.17 KEY70628.1 - 0.00019 21.3 0.0 0.095 12.5 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase TIP49 PF06068.8 KEY70628.1 - 0.00068 18.4 0.0 0.63 8.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus RNA_helicase PF00910.17 KEY70628.1 - 0.00076 19.6 0.0 0.89 9.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Viral_helicase1 PF01443.13 KEY70628.1 - 0.00081 18.9 0.0 0.32 10.4 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.16 KEY70628.1 - 0.0015 17.7 0.1 0.84 8.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KEY70628.1 - 0.002 17.6 0.0 0.066 12.6 0.0 2.5 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 KEY70628.1 - 0.0025 17.2 3.0 7.2 5.9 0.1 3.8 2 2 2 4 4 4 0 AAA domain Arch_ATPase PF01637.13 KEY70628.1 - 0.0031 17.2 0.0 0.74 9.4 0.0 3.2 2 2 1 3 3 3 1 Archaeal ATPase NB-ARC PF00931.17 KEY70628.1 - 0.0041 16.0 0.1 1.1 8.0 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.22 KEY70628.1 - 0.0056 16.9 0.1 1.4 9.2 0.0 3.0 3 0 0 3 3 2 1 ABC transporter Cytidylate_kin2 PF13189.1 KEY70628.1 - 0.008 16.1 0.0 5.3 6.9 0.0 2.6 2 1 0 2 2 2 0 Cytidylate kinase-like family KaiC PF06745.8 KEY70628.1 - 0.011 14.9 0.0 1.5 7.9 0.0 2.4 2 0 0 2 2 2 0 KaiC APS_kinase PF01583.15 KEY70628.1 - 0.011 15.3 0.1 0.043 13.4 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase KAP_NTPase PF07693.9 KEY70628.1 - 0.017 14.1 0.6 1.1 8.2 0.0 2.5 1 1 1 2 2 2 0 KAP family P-loop domain AAA_3 PF07726.6 KEY70628.1 - 0.017 14.7 0.0 6.7 6.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KEY70628.1 - 0.018 13.9 0.0 0.23 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) KTI12 PF08433.5 KEY70628.1 - 0.02 14.0 0.0 0.14 11.3 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 cobW PF02492.14 KEY70628.1 - 0.036 13.5 0.2 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 KEY70628.1 - 0.054 13.0 0.3 7.8 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KEY70628.1 - 0.073 12.0 0.0 11 4.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 KEY70628.1 - 0.099 12.3 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 NTPase PhoH PF02562.11 KEY70628.1 - 0.1 11.8 0.0 11 5.1 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein PduV-EutP PF10662.4 KEY70628.1 - 0.23 10.9 0.4 4.5 6.7 0.0 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Zot PF05707.7 KEY70629.1 - 0.0095 15.4 0.0 0.024 14.0 0.0 1.7 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Gal4_dimer PF03902.8 KEY70629.1 - 0.13 12.1 4.0 6.1 6.8 0.0 3.4 3 0 0 3 3 3 0 Gal4-like dimerisation domain Inositol_P PF00459.20 KEY70630.1 - 2.6e-43 148.2 0.0 4.3e-43 147.5 0.0 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family SNF2_N PF00176.18 KEY70631.1 - 8.1e-63 211.9 0.0 1.5e-62 211.0 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 KEY70631.1 - 7.9e-27 92.7 5.7 5.8e-15 54.7 0.3 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KEY70631.1 - 9e-14 51.1 0.0 2.5e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ABC_tran PF00005.22 KEY70632.1 - 3.7e-33 114.7 0.0 3.1e-15 56.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 KEY70632.1 - 2e-12 46.4 4.5 2e-12 46.4 3.1 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 KEY70632.1 - 2.5e-12 47.3 6.8 0.055 13.4 0.0 4.5 3 2 2 5 5 4 4 AAA domain SMC_N PF02463.14 KEY70632.1 - 8.2e-12 44.8 0.4 0.00014 21.1 0.0 3.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KEY70632.1 - 2.5e-07 30.1 0.1 1 8.3 0.0 4.4 5 0 0 5 5 5 1 AAA ATPase domain AAA_17 PF13207.1 KEY70632.1 - 2.8e-06 28.1 0.2 0.043 14.6 0.0 2.9 2 2 0 2 2 2 2 AAA domain Fer4 PF00037.22 KEY70632.1 - 9.6e-06 24.9 2.7 9.6e-06 24.9 1.9 2.6 3 0 0 3 3 2 1 4Fe-4S binding domain AAA PF00004.24 KEY70632.1 - 2e-05 24.7 0.0 0.012 15.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KEY70632.1 - 2.2e-05 24.7 0.0 0.27 11.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 KEY70632.1 - 6.2e-05 22.4 0.2 0.075 12.5 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KEY70632.1 - 9.6e-05 22.5 0.0 0.017 15.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.1 KEY70632.1 - 0.00022 21.0 10.1 0.0004 20.1 7.0 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_23 PF13476.1 KEY70632.1 - 0.00028 21.2 0.1 0.015 15.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KEY70632.1 - 0.00054 20.1 0.1 0.26 11.4 0.0 2.7 2 0 0 2 2 2 1 RNA helicase DUF258 PF03193.11 KEY70632.1 - 0.00055 19.1 2.1 1 8.5 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KEY70632.1 - 0.0008 19.4 0.0 0.17 11.8 0.0 2.5 3 0 0 3 3 2 1 AAA ATPase domain MobB PF03205.9 KEY70632.1 - 0.0009 18.9 0.6 0.17 11.5 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KEY70632.1 - 0.0013 18.4 0.1 0.41 10.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 KEY70632.1 - 0.0013 18.3 0.2 0.017 14.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 KEY70632.1 - 0.0017 17.8 0.0 1.2 8.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain VirE PF05272.6 KEY70632.1 - 0.0017 17.8 0.1 1.7 8.0 0.0 2.6 2 0 0 2 2 2 1 Virulence-associated protein E AAA_33 PF13671.1 KEY70632.1 - 0.0025 17.6 0.0 0.21 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.2 KEY70632.1 - 0.0027 18.0 6.9 0.0066 16.8 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain SRP54 PF00448.17 KEY70632.1 - 0.0027 17.1 2.2 0.11 11.9 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_6 PF12837.2 KEY70632.1 - 0.0068 16.2 1.6 0.0068 16.2 1.1 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_13 PF13166.1 KEY70632.1 - 0.013 13.9 0.0 0.013 13.9 0.0 2.3 4 0 0 4 4 3 0 AAA domain Rad17 PF03215.10 KEY70632.1 - 0.02 13.5 0.0 0.12 11.0 0.0 1.9 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Thymidylate_kin PF02223.12 KEY70632.1 - 0.027 13.8 0.8 4.4 6.6 0.0 3.0 3 0 0 3 3 3 0 Thymidylate kinase AAA_5 PF07728.9 KEY70632.1 - 0.027 14.1 1.4 0.41 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Fer4_10 PF13237.1 KEY70632.1 - 0.028 14.2 1.6 0.028 14.2 1.1 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Miro PF08477.8 KEY70632.1 - 0.028 14.9 0.1 1.9 8.9 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein AAA_28 PF13521.1 KEY70632.1 - 0.057 13.3 0.1 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fer4_16 PF13484.1 KEY70632.1 - 0.079 13.7 0.2 0.079 13.7 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain NB-ARC PF00931.17 KEY70632.1 - 0.11 11.3 0.0 5.4 5.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain SbcCD_C PF13558.1 KEY70632.1 - 0.16 11.9 0.1 9.9 6.1 0.0 3.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 KEY70632.1 - 0.18 11.3 0.1 4.1 6.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.1 KEY70632.1 - 0.19 11.7 8.7 0.61 10.1 6.2 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain PduV-EutP PF10662.4 KEY70632.1 - 0.22 10.9 3.5 0.38 10.2 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 KEY70632.1 - 0.33 10.8 1.4 24 4.8 0.0 3.1 2 2 1 3 3 3 0 AAA domain NTPase_1 PF03266.10 KEY70632.1 - 0.35 10.5 1.7 14 5.3 0.0 2.5 2 0 0 2 2 2 0 NTPase Fer4_2 PF12797.2 KEY70632.1 - 0.47 10.4 11.7 0.21 11.6 1.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_24 PF13479.1 KEY70632.1 - 0.61 9.6 2.0 3.1 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.1 KEY70632.1 - 1.4 9.2 13.7 0.055 13.7 1.5 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain FF PF01846.14 KEY70633.1 - 9.7e-50 166.3 11.8 4.2e-13 49.0 0.1 6.4 6 0 0 6 6 6 5 FF domain WW PF00397.21 KEY70633.1 - 3.1e-18 65.2 16.2 5.5e-10 38.9 4.0 2.6 2 0 0 2 2 2 2 WW domain Trs65 PF12735.2 KEY70634.1 - 8.8e-72 242.0 0.0 1.2e-71 241.5 0.0 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 SLD3 PF08639.5 KEY70635.1 - 2.2e-107 359.7 0.1 3.1e-107 359.2 0.0 1.2 1 0 0 1 1 1 1 DNA replication regulator SLD3 Homeobox PF00046.24 KEY70636.1 - 5.6e-15 54.7 3.0 1.3e-14 53.5 2.1 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KEY70636.1 - 0.037 13.7 0.7 0.095 12.4 0.5 1.7 1 0 0 1 1 1 0 Homeobox KN domain DUF3741 PF12552.3 KEY70636.1 - 0.51 10.0 2.6 13 5.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3741) HAD_2 PF13419.1 KEY70637.1 - 3e-15 56.8 0.0 3.9e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEY70637.1 - 1.1e-09 37.9 0.0 1.8e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KEY70637.1 - 2.8e-09 37.7 0.0 9.6e-08 32.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEY70637.1 - 0.00015 21.9 0.0 0.0002 21.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KEY70637.1 - 0.0078 16.0 0.1 0.086 12.7 0.1 2.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase GHL6 PF14871.1 KEY70637.1 - 0.054 13.5 0.5 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Peptidase_C15 PF01470.12 KEY70638.1 - 4.4e-10 39.7 0.0 1.7e-07 31.2 0.0 2.9 1 1 0 1 1 1 1 Pyroglutamyl peptidase DUF4110 PF13422.1 KEY70640.1 - 3.2e-27 94.2 0.4 3.2e-27 94.2 0.3 3.6 5 0 0 5 5 5 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 KEY70640.1 - 7.1e-26 89.7 11.7 1.7e-07 31.1 0.1 6.5 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.1 KEY70640.1 - 5.3e-22 77.3 15.0 5.1e-06 26.1 0.0 6.5 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KEY70640.1 - 2.2e-17 62.5 3.3 8.4e-06 25.6 0.0 5.6 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 KEY70640.1 - 3.4e-15 55.1 2.8 6.5e-06 25.7 0.1 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 KEY70640.1 - 5.7e-13 48.4 1.6 0.025 14.7 0.1 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 KEY70640.1 - 3.8e-11 42.3 0.7 0.00023 20.6 0.1 5.2 5 0 0 5 5 5 3 Kelch motif ArsA_ATPase PF02374.10 KEY70640.1 - 0.048 12.7 0.9 0.52 9.2 0.0 2.1 2 0 0 2 2 2 0 Anion-transporting ATPase Methyltransf_15 PF09445.5 KEY70641.1 - 3.1e-41 140.6 0.0 4.2e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 KEY70641.1 - 2.4e-06 27.5 0.0 3.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY70641.1 - 1.1e-05 25.9 0.0 1.4e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KEY70641.1 - 0.00033 20.3 0.0 0.00047 19.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 KEY70641.1 - 0.0036 16.9 0.0 0.0052 16.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY70641.1 - 0.019 14.3 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.15 KEY70641.1 - 0.02 13.8 0.0 0.03 13.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Cons_hypoth95 PF03602.10 KEY70641.1 - 0.021 14.2 0.0 0.037 13.4 0.0 1.4 1 1 0 1 1 1 0 Conserved hypothetical protein 95 UPF0020 PF01170.13 KEY70641.1 - 0.036 13.6 0.0 0.051 13.1 0.0 1.4 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 GRASP55_65 PF04495.9 KEY70642.1 - 5.9e-47 159.1 0.0 6e-46 155.8 0.0 2.0 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain DAD PF02109.11 KEY70643.1 - 3e-48 162.5 1.8 3.7e-48 162.2 1.3 1.0 1 0 0 1 1 1 1 DAD family DUF1180 PF06679.7 KEY70643.1 - 0.058 13.2 1.4 0.083 12.7 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Tmemb_14 PF03647.8 KEY70644.1 - 2.1e-24 85.7 7.0 2.4e-24 85.5 4.9 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Cmc1 PF08583.5 KEY70645.1 - 1.1e-15 57.1 4.4 1.3e-15 56.8 3.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DDOST_48kD PF03345.9 KEY70645.1 - 0.035 12.6 0.0 0.037 12.5 0.0 1.0 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta COX17 PF05051.8 KEY70645.1 - 0.33 11.0 2.3 11 6.0 0.2 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Prefoldin_2 PF01920.15 KEY70646.1 - 6.8e-25 86.8 8.8 7.9e-25 86.6 6.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit Mnd1 PF03962.10 KEY70646.1 - 0.016 14.8 1.4 0.026 14.1 1.0 1.3 1 1 0 1 1 1 0 Mnd1 family Prefoldin PF02996.12 KEY70646.1 - 0.03 13.9 6.8 0.11 12.1 0.4 2.2 1 1 1 2 2 2 0 Prefoldin subunit Ribosomal_L17 PF01196.14 KEY70646.1 - 0.067 13.7 0.3 0.13 12.8 0.2 1.5 1 1 1 2 2 2 0 Ribosomal protein L17 STAT_alpha PF01017.15 KEY70646.1 - 0.074 12.7 5.7 0.096 12.3 4.0 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain DUF4279 PF14106.1 KEY70646.1 - 0.077 12.8 1.3 2.3 8.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) CDC37_N PF03234.9 KEY70646.1 - 0.079 13.2 3.7 0.095 13.0 2.6 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Tho2 PF11262.3 KEY70646.1 - 0.099 11.6 1.1 0.6 9.1 0.8 1.8 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Syntaxin-6_N PF09177.6 KEY70646.1 - 0.099 13.0 1.1 2.9 8.3 0.1 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF4200 PF13863.1 KEY70646.1 - 0.11 12.4 0.7 0.11 12.4 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) GAS PF13851.1 KEY70646.1 - 0.12 11.5 8.4 0.71 9.0 5.8 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding p25-alpha PF05517.7 KEY70646.1 - 0.26 11.5 1.9 3.2 7.9 0.0 2.0 2 0 0 2 2 2 0 p25-alpha TMF_DNA_bd PF12329.3 KEY70646.1 - 0.39 10.5 7.4 0.45 10.3 0.6 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 KEY70646.1 - 0.48 10.0 6.0 1.1 8.7 4.1 1.6 1 1 0 1 1 1 0 IncA protein Cytochrom_B562 PF07361.6 KEY70646.1 - 0.65 10.4 6.0 1.2 9.5 0.7 2.1 2 0 0 2 2 2 0 Cytochrome b562 Spc24 PF08286.6 KEY70646.1 - 0.76 9.4 6.2 1.8 8.2 0.2 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FliJ PF02050.11 KEY70646.1 - 0.85 9.6 9.2 2 8.5 1.5 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein CBFD_NFYB_HMF PF00808.18 KEY70647.1 - 2e-26 91.7 1.8 5.1e-26 90.5 0.9 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KEY70647.1 - 3.7e-07 30.1 0.1 6.6e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 KEY70647.1 - 0.00096 18.9 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 KEY70647.1 - 0.0017 18.0 0.0 0.0034 17.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Ofd1_CTDD PF10637.4 KEY70647.1 - 0.043 12.9 0.7 0.061 12.4 0.4 1.3 1 1 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term TFIID_20kDa PF03847.8 KEY70647.1 - 0.043 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A EST1_DNA_bind PF10373.4 KEY70647.1 - 0.099 11.8 0.1 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain RRN3 PF05327.6 KEY70648.1 - 6.2e-165 549.5 0.0 9.1e-165 548.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 MinE PF03776.9 KEY70648.1 - 0.16 11.4 0.4 0.38 10.2 0.3 1.5 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE bZIP_1 PF00170.16 KEY70649.1 - 0.49 10.4 12.5 6.2 6.8 8.6 2.2 1 1 0 1 1 1 0 bZIP transcription factor Dmrt1 PF12374.3 KEY70649.1 - 0.58 10.5 4.1 5 7.5 0.4 2.5 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Dopey_N PF04118.9 KEY70650.1 - 2.4e-116 387.8 0.0 5.2e-116 386.7 0.0 1.5 1 0 0 1 1 1 1 Dopey, N-terminal Mon1 PF03164.9 KEY70651.1 - 5.8e-114 380.9 0.0 6.9e-114 380.6 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 COesterase PF00135.23 KEY70654.1 - 5e-87 292.8 0.0 6.2e-87 292.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEY70654.1 - 0.00014 21.5 0.2 0.00023 20.8 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Herpes_US9 PF06072.6 KEY70654.1 - 0.35 10.7 0.0 0.35 10.7 0.0 1.8 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 F-box-like PF12937.2 KEY70656.1 - 0.00037 20.1 0.1 0.00072 19.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like TMEM154 PF15102.1 KEY70657.1 - 6.8e-05 22.6 0.1 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family DUF1180 PF06679.7 KEY70657.1 - 0.0019 18.1 1.1 0.0056 16.5 0.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Menin PF05053.8 KEY70657.1 - 0.008 14.4 1.9 0.012 13.8 1.3 1.2 1 0 0 1 1 1 1 Menin Glycophorin_A PF01102.13 KEY70657.1 - 0.02 14.6 3.3 0.023 14.4 1.4 1.9 1 1 0 1 1 1 0 Glycophorin A Rifin_STEVOR PF02009.11 KEY70657.1 - 0.043 13.4 0.0 0.062 12.9 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family EphA2_TM PF14575.1 KEY70657.1 - 0.08 13.3 0.0 0.29 11.5 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Herpes_capsid PF06112.6 KEY70657.1 - 0.54 10.2 15.8 1.4 8.9 10.9 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Fungal_trans_2 PF11951.3 KEY70659.1 - 5e-82 275.5 1.6 6.2e-82 275.2 1.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY70659.1 - 1.9e-08 34.0 6.6 3.1e-08 33.3 4.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAM_2 PF07647.12 KEY70661.1 - 3.9e-05 23.4 0.0 7.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 KEY70661.1 - 0.00021 21.4 0.0 0.001 19.2 0.0 2.2 3 0 0 3 3 3 1 PH domain SAM_1 PF00536.25 KEY70661.1 - 0.19 11.9 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Sod_Fe_C PF02777.13 KEY70662.1 - 3e-11 43.1 0.0 0.0001 22.1 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain DUF3661 PF12400.3 KEY70663.1 - 9.5e-42 142.1 3.4 1.6e-41 141.4 2.4 1.4 1 0 0 1 1 1 1 Vaculolar membrane protein SDF PF00375.13 KEY70663.1 - 0.23 10.1 4.7 0.34 9.6 0.0 2.4 2 1 0 2 2 2 0 Sodium:dicarboxylate symporter family RCR PF12273.3 KEY70665.1 - 4.3e-15 56.4 24.3 1.1e-13 51.8 16.8 2.5 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF1183 PF06682.7 KEY70665.1 - 0.0047 16.5 3.2 0.0047 16.5 2.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) DUF1191 PF06697.7 KEY70665.1 - 0.022 13.5 0.2 0.031 13.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Rhabdo_glycop PF00974.13 KEY70665.1 - 0.034 12.3 0.4 0.049 11.8 0.3 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DUF2668 PF10873.3 KEY70665.1 - 0.05 13.7 0.1 0.05 13.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) WBP-1 PF11669.3 KEY70665.1 - 0.065 13.3 3.8 0.19 11.8 2.6 1.9 1 1 0 1 1 1 0 WW domain-binding protein 1 Ferric_reduct PF01794.14 KEY70665.1 - 0.07 13.2 0.1 0.096 12.7 0.1 1.2 1 0 0 1 1 1 0 Ferric reductase like transmembrane component DUF3611 PF12263.3 KEY70665.1 - 0.08 12.3 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) 7TMR-DISM_7TM PF07695.6 KEY70665.1 - 0.094 12.3 0.2 0.13 11.9 0.2 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling TPPK_C PF12555.3 KEY70665.1 - 0.13 11.9 1.4 0.22 11.2 1.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Shisa PF13908.1 KEY70665.1 - 0.31 11.2 3.7 0.67 10.1 2.5 1.7 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator FAD_binding_3 PF01494.14 KEY70666.1 - 1.4e-23 83.5 0.0 3.9e-23 82.0 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KEY70666.1 - 9.6e-05 22.3 0.2 0.00044 20.2 0.2 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEY70666.1 - 0.00032 19.7 0.0 0.0066 15.3 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KEY70666.1 - 0.0021 17.6 0.2 0.0045 16.5 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 KEY70666.1 - 0.0027 16.7 0.2 0.036 12.9 0.2 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KEY70666.1 - 0.0031 16.6 0.2 0.0051 15.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KEY70666.1 - 0.0052 15.6 0.8 0.01 14.6 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 KEY70666.1 - 0.014 14.0 0.9 0.076 11.6 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.22 KEY70666.1 - 0.051 13.9 0.8 0.13 12.6 0.4 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEY70666.1 - 0.084 12.7 0.5 0.17 11.7 0.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HET PF06985.6 KEY70667.1 - 8.8e-30 103.6 0.0 3.1e-29 101.9 0.0 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CagX PF03524.10 KEY70668.1 - 0.081 12.1 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 Conjugal transfer protein tRNA_synt_1c_R2 PF04557.10 KEY70668.1 - 0.13 13.0 1.7 0.15 12.7 0.4 1.6 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 CPSase_L_D2 PF02786.12 KEY70669.1 - 1.1e-80 269.8 0.4 1.7e-80 269.2 0.3 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 KEY70669.1 - 2.8e-65 219.4 0.0 5.2e-65 218.5 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 KEY70669.1 - 5e-35 119.9 0.0 1e-34 118.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KEY70669.1 - 4e-31 107.1 0.0 1.5e-30 105.3 0.0 2.1 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 KEY70669.1 - 1.2e-25 90.5 0.0 2.2e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 KEY70669.1 - 3e-19 69.4 0.2 6.1e-19 68.4 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KEY70669.1 - 8.2e-19 67.0 0.5 2.2e-18 65.6 0.4 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KEY70669.1 - 6e-14 51.5 0.0 4.6e-13 48.6 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 KEY70669.1 - 3.9e-12 45.6 2.1 5.2e-07 29.2 0.0 3.5 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 KEY70669.1 - 2.2e-10 40.2 0.0 4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KEY70669.1 - 3.9e-07 29.5 0.1 7.8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KEY70669.1 - 5.2e-06 26.0 0.0 1.9e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_2 PF12700.2 KEY70669.1 - 1.9e-05 24.0 0.0 0.04 13.0 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein HlyD PF00529.15 KEY70669.1 - 6.3e-05 22.4 0.0 0.0023 17.2 0.0 2.4 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 KEY70669.1 - 0.00025 21.3 0.0 0.51 10.7 0.0 3.1 3 0 0 3 3 2 1 HlyD family secretion protein ATP-grasp_3 PF02655.9 KEY70669.1 - 0.0003 20.6 0.0 0.00068 19.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain DUF2118 PF09891.4 KEY70669.1 - 0.0057 16.3 0.2 0.028 14.1 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2118) NQRA PF05896.6 KEY70669.1 - 0.011 14.9 0.1 0.02 14.0 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GARS_A PF01071.14 KEY70669.1 - 0.018 14.6 0.0 0.068 12.7 0.0 1.9 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RnfC_N PF13375.1 KEY70669.1 - 0.024 14.3 0.4 0.068 12.8 0.3 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain SUI1 PF01253.17 KEY70669.1 - 0.1 12.3 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 Translation initiation factor SUI1 Rieske PF00355.21 KEY70669.1 - 0.13 11.8 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain DUF3572 PF12096.3 KEY70669.1 - 0.13 12.0 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3572) FAD_binding_2 PF00890.19 KEY70670.1 - 2.4e-123 412.1 4.0 3e-123 411.7 2.8 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 KEY70670.1 - 2e-47 160.2 0.9 3e-47 159.6 0.6 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 KEY70670.1 - 4.9e-07 29.8 0.1 0.0049 16.7 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEY70670.1 - 2.5e-05 23.4 0.3 0.028 13.5 0.0 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 KEY70670.1 - 0.00012 21.0 1.3 0.038 12.8 1.3 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 KEY70670.1 - 0.0021 17.0 1.6 0.005 15.7 0.5 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KEY70670.1 - 0.0039 16.3 0.1 0.0039 16.3 0.1 1.8 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 KEY70670.1 - 0.23 9.8 1.1 0.73 8.2 0.3 2.0 2 0 0 2 2 2 0 HI0933-like protein EXS PF03124.9 KEY70671.1 - 2.8e-104 348.8 7.7 3.2e-104 348.6 5.4 1.0 1 0 0 1 1 1 1 EXS family Pex2_Pex12 PF04757.9 KEY70672.1 - 1e-35 123.2 3.5 1.5e-35 122.7 2.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 KEY70672.1 - 2e-12 46.7 7.8 3.1e-12 46.1 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEY70672.1 - 3.5e-12 46.1 7.6 5.3e-12 45.5 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEY70672.1 - 6.4e-10 38.5 6.7 9.8e-10 37.9 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEY70672.1 - 7.2e-10 38.3 5.8 1.1e-09 37.7 4.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY70672.1 - 1.2e-08 34.5 5.5 1.8e-08 33.9 3.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KEY70672.1 - 1.2e-06 28.2 8.2 2e-06 27.5 5.7 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KEY70672.1 - 1.2e-05 24.9 2.4 2.3e-05 24.0 1.7 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 KEY70672.1 - 9.4e-05 22.4 7.1 0.00021 21.3 4.9 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KEY70672.1 - 0.0002 21.0 4.5 0.00048 19.7 3.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 KEY70672.1 - 0.0034 16.8 2.5 0.0057 16.1 1.7 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 KEY70672.1 - 0.041 13.7 2.2 0.073 12.9 1.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KEY70672.1 - 0.042 13.4 7.7 0.078 12.5 5.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TerY-C PF15616.1 KEY70672.1 - 0.072 13.0 2.3 0.12 12.2 1.6 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain IBR PF01485.16 KEY70672.1 - 3.7 7.4 8.4 11 6.0 5.8 1.8 1 1 0 1 1 1 0 IBR domain zf-LYAR PF08790.6 KEY70673.1 - 0.026 14.2 3.1 0.19 11.4 0.3 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger 2OG-FeII_Oxy_5 PF13759.1 KEY70673.1 - 0.085 13.1 2.1 18 5.7 1.0 2.6 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Lenti_VIF_2 PF07401.7 KEY70674.1 - 0.12 11.4 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Bovine Lentivirus VIF protein Abhydrolase_5 PF12695.2 KEY70675.1 - 9.8e-23 80.5 0.0 1.4e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY70675.1 - 7.6e-20 71.7 0.0 2e-18 67.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY70675.1 - 9.5e-07 28.6 0.1 0.0021 17.6 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KEY70675.1 - 0.00017 21.0 0.0 0.14 11.5 0.0 2.3 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase DUF818 PF05677.7 KEY70675.1 - 0.00029 19.6 0.1 0.00042 19.1 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.16 KEY70675.1 - 0.00035 19.8 0.0 0.002 17.3 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.8 KEY70675.1 - 0.00049 19.6 0.0 0.0015 18.0 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 KEY70675.1 - 0.0075 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 KEY70675.1 - 0.025 13.1 0.1 3 6.2 0.0 2.8 2 1 1 3 3 3 0 Acetyl xylan esterase (AXE1) DLH PF01738.13 KEY70675.1 - 0.042 13.1 0.0 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S15 PF02129.13 KEY70675.1 - 0.11 11.8 0.0 0.43 9.9 0.0 1.8 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) R3H PF01424.17 KEY70676.1 - 4.6e-14 51.8 0.2 9.1e-14 50.9 0.1 1.5 1 0 0 1 1 1 1 R3H domain Baculo_RING PF05883.6 KEY70676.1 - 0.042 13.6 1.9 0.08 12.7 1.3 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-NF-X1 PF01422.12 KEY70676.1 - 4 7.4 69.0 0.038 13.9 7.7 5.7 5 0 0 5 5 5 0 NF-X1 type zinc finger WSC PF01822.14 KEY70677.1 - 3.2e-71 235.2 57.3 4.6e-21 74.5 5.2 4.4 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.6 KEY70677.1 - 6.5e-29 100.6 0.0 2.7e-27 95.4 0.0 3.1 3 1 1 4 4 4 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KEY70677.1 - 3.8e-21 75.0 0.0 6.7e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) GPS PF01825.16 KEY70677.1 - 3.4 7.8 11.8 20 5.4 0.3 4.3 4 0 0 4 4 4 0 Latrophilin/CL-1-like GPS domain SnoaL PF07366.7 KEY70679.1 - 8.2e-20 70.6 0.1 2.8e-16 59.2 0.0 2.1 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KEY70679.1 - 1.2e-09 38.4 0.1 1.4e-05 25.4 0.0 2.4 2 0 0 2 2 2 2 SnoaL-like domain zf-CCHC PF00098.18 KEY70682.1 - 0.0033 17.2 1.6 0.0081 16.0 1.1 1.7 1 0 0 1 1 1 1 Zinc knuckle Nic96 PF04097.9 KEY70683.1 - 1.5e-204 680.6 0.0 1.8e-204 680.3 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 KEY70683.1 - 5.5e-08 33.0 83.3 2.4e-06 27.7 23.2 3.4 2 1 1 3 3 3 2 Nucleoporin FG repeat region FGGY_C PF02782.11 KEY70684.1 - 6e-46 156.5 0.2 1e-45 155.8 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KEY70684.1 - 8.7e-23 80.8 1.4 1e-19 70.8 0.0 3.0 3 1 0 3 3 3 2 FGGY family of carbohydrate kinases, N-terminal domain VTC PF09359.5 KEY70685.1 - 5.2e-90 301.2 1.3 7.9e-90 300.7 0.9 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 KEY70685.1 - 8.7e-14 51.9 26.5 1.9e-13 50.8 8.6 4.3 3 1 0 3 3 3 1 SPX domain DUF202 PF02656.10 KEY70685.1 - 1.2e-09 38.2 2.2 2.5e-09 37.2 1.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Glu_synthase PF01645.12 KEY70686.1 - 2.3e-159 530.2 0.0 4e-159 529.4 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 KEY70686.1 - 1.1e-139 465.1 0.0 1.5e-139 464.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 KEY70686.1 - 1.1e-117 392.4 0.0 1.9e-117 391.6 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 KEY70686.1 - 9.2e-68 227.2 1.3 1.7e-67 226.3 0.9 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 KEY70686.1 - 2.8e-22 78.4 0.0 6.8e-22 77.2 0.0 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 KEY70686.1 - 1.3e-14 54.6 0.0 5.4e-14 52.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY70686.1 - 8.8e-09 35.7 0.3 0.0044 17.0 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY70686.1 - 2.9e-08 33.6 0.0 1.2e-07 31.6 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KEY70686.1 - 8.9e-08 32.4 0.3 0.00059 20.1 0.1 3.4 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KEY70686.1 - 9.2e-06 24.9 0.3 3e-05 23.2 0.1 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 KEY70686.1 - 3.7e-05 22.3 0.1 7.8e-05 21.3 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 KEY70686.1 - 0.00016 20.7 0.7 0.0007 18.6 0.1 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEY70686.1 - 0.0006 18.7 0.1 0.002 17.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KEY70686.1 - 0.0011 18.1 0.2 0.0023 17.1 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KEY70686.1 - 0.0025 18.0 1.0 3.1 8.0 0.0 2.9 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_3 PF01494.14 KEY70686.1 - 0.0093 15.0 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.14 KEY70686.1 - 0.01 14.1 0.1 0.79 7.8 0.0 2.8 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Thi4 PF01946.12 KEY70686.1 - 0.011 14.9 0.1 0.032 13.3 0.0 1.8 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 KEY70686.1 - 0.013 15.0 0.0 0.59 9.6 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FMN_dh PF01070.13 KEY70686.1 - 0.046 12.5 0.9 0.34 9.6 0.7 2.1 2 0 0 2 2 2 0 FMN-dependent dehydrogenase NAD_Gly3P_dh_N PF01210.18 KEY70686.1 - 0.074 12.7 0.0 0.28 10.8 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AdoHcyase_NAD PF00670.16 KEY70686.1 - 0.092 12.5 0.4 8.7 6.1 0.1 3.0 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GIDA PF01134.17 KEY70686.1 - 0.66 8.7 2.1 0.66 8.7 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Apc15p PF05841.6 KEY70688.1 - 4.5e-19 69.4 1.6 4.5e-19 69.4 1.1 3.0 2 1 0 2 2 2 1 Apc15p protein CHZ PF09649.5 KEY70689.1 - 1.8e-15 55.8 0.8 1.8e-15 55.8 0.5 2.4 3 1 0 3 3 3 1 Histone chaperone domain CHZ SNARE PF05739.14 KEY70689.1 - 4.1e-09 35.9 1.9 6.7e-09 35.3 1.3 1.4 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 KEY70689.1 - 0.0048 16.3 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 Cyclin PF08613.6 KEY70691.1 - 1.5e-29 103.2 0.0 4.8e-29 101.6 0.0 1.9 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 KEY70691.1 - 0.00015 21.3 0.1 0.00022 20.7 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Arm PF00514.18 KEY70692.1 - 2.3e-07 30.3 7.7 0.024 14.4 0.0 7.1 7 1 0 7 7 7 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KEY70692.1 - 0.00041 20.7 19.5 0.12 12.9 0.0 6.9 7 0 0 7 7 7 3 HEAT-like repeat HEAT PF02985.17 KEY70692.1 - 0.0049 16.8 24.6 0.31 11.2 0.1 8.2 9 1 1 10 10 10 3 HEAT repeat Velvet PF11754.3 KEY70693.1 - 1.5e-62 210.8 0.0 2.7e-62 209.9 0.0 1.4 1 0 0 1 1 1 1 Velvet factor TIG PF01833.19 KEY70695.1 - 5.8e-10 39.0 0.0 1.6e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 IPT/TIG domain Cauli_VI PF01693.11 KEY70696.1 - 5.6e-31 106.2 5.6 1.6e-15 56.8 0.4 2.6 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 KEY70696.1 - 2.4e-28 99.0 0.0 4.6e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 RNase H dCMP_cyt_deam_1 PF00383.17 KEY70697.1 - 4e-07 29.6 0.0 8.4e-07 28.5 0.0 1.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region 6PF2K PF01591.13 KEY70698.1 - 8.3e-65 217.9 0.0 8.2e-45 152.5 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KEY70698.1 - 3.6e-26 92.1 0.1 2e-25 89.7 0.0 2.2 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KEY70698.1 - 9.5e-06 25.5 0.0 6.7e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEY70698.1 - 0.00061 20.6 0.0 0.0038 18.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain CARD PF00619.16 KEY70698.1 - 0.017 14.9 0.1 0.074 12.8 0.1 2.0 1 1 0 1 1 1 0 Caspase recruitment domain KTI12 PF08433.5 KEY70698.1 - 0.022 13.9 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 WD40 PF00400.27 KEY70699.1 - 2e-39 132.0 4.5 1.2e-08 34.5 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Sof1 PF04158.9 KEY70699.1 - 3.1e-31 107.2 14.6 5.8e-31 106.3 10.1 1.5 1 0 0 1 1 1 1 Sof1-like domain Cytochrom_D1 PF02239.11 KEY70699.1 - 0.00064 18.1 0.3 0.048 11.9 0.1 2.6 1 1 1 2 2 2 2 Cytochrome D1 heme domain RNA_pol_A_bac PF01000.21 KEY70700.1 - 1.7e-32 111.8 0.0 2.5e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KEY70700.1 - 4e-14 51.4 0.0 5.1e-14 51.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Mito_carr PF00153.22 KEY70701.1 - 1.9e-45 152.4 0.0 1.8e-17 62.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_2d PF01409.15 KEY70702.1 - 1.5e-46 158.5 0.7 4.2e-24 85.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 KEY70702.1 - 5.9e-27 93.6 0.0 1.5e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Calcipressin PF04847.7 KEY70703.1 - 4.3e-50 169.8 0.0 5.1e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Calcipressin Limkain-b1 PF11608.3 KEY70703.1 - 0.033 13.9 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 DUF2236 PF09995.4 KEY70704.1 - 6.1e-30 104.2 0.2 1e-29 103.5 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Neugrin PF06413.6 KEY70705.1 - 9.6e-09 35.3 0.3 9.6e-09 35.3 0.2 2.0 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.2 KEY70705.1 - 2.8e-06 27.3 1.3 2.8e-06 27.3 0.9 1.8 2 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 adh_short PF00106.20 KEY70706.1 - 7.7e-30 103.9 2.0 1.5e-29 103.0 1.4 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY70706.1 - 3.7e-12 46.2 4.2 2e-10 40.6 2.3 2.9 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 KEY70706.1 - 3.4e-11 43.3 0.0 4.6e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KEY70706.1 - 0.093 12.7 0.3 0.18 11.7 0.2 1.5 1 0 0 1 1 1 0 NADH(P)-binding Pkinase PF00069.20 KEY70707.1 - 4.2e-11 42.4 0.0 1.4e-10 40.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY70707.1 - 0.0017 17.5 0.0 0.019 14.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Glyco_hydro_72 PF03198.9 KEY70708.1 - 9.2e-98 327.0 0.2 1.5e-97 326.3 0.2 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Arginase PF00491.16 KEY70708.1 - 0.028 13.7 0.2 0.044 13.0 0.1 1.2 1 0 0 1 1 1 0 Arginase family TRF PF08558.5 KEY70709.1 - 5.9e-19 68.3 0.0 1.1e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 KEY70709.1 - 3.9e-07 30.0 0.1 5.6e-06 26.3 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEY70709.1 - 0.008 16.2 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain bZIP_1 PF00170.16 KEY70710.1 - 0.00023 21.0 14.8 0.63 10.0 2.5 4.4 2 1 2 4 4 4 2 bZIP transcription factor Herpes_BLRF2 PF05812.7 KEY70710.1 - 0.00072 19.3 1.7 0.00072 19.3 1.2 2.1 1 1 1 2 2 2 1 Herpesvirus BLRF2 protein UPF0242 PF06785.6 KEY70710.1 - 0.0008 18.1 6.0 0.0008 18.1 4.1 1.7 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) ATG16 PF08614.6 KEY70710.1 - 0.0025 17.6 12.3 0.0031 17.3 7.6 1.7 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.7 KEY70710.1 - 0.0039 16.9 6.2 0.0039 16.9 4.3 2.6 1 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein MbeD_MobD PF04899.7 KEY70710.1 - 0.0054 16.6 1.0 0.015 15.1 0.3 2.1 1 1 0 1 1 1 1 MbeD/MobD like TBPIP PF07106.8 KEY70710.1 - 0.0072 15.8 3.7 0.0072 15.8 2.6 2.4 1 1 1 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 KEY70710.1 - 0.0074 16.6 13.0 0.67 10.3 3.5 3.4 1 1 1 2 2 2 1 Protein of unknown function (DUF972) HOOK PF05622.7 KEY70710.1 - 0.0093 13.8 14.1 0.052 11.3 3.0 2.0 1 1 1 2 2 2 2 HOOK protein TMF_TATA_bd PF12325.3 KEY70710.1 - 0.016 14.9 6.5 0.016 14.9 4.5 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Ax_dynein_light PF10211.4 KEY70710.1 - 0.021 14.6 12.0 0.23 11.2 0.7 2.6 2 1 0 2 2 2 0 Axonemal dynein light chain PspA_IM30 PF04012.7 KEY70710.1 - 0.024 14.0 4.9 0.013 14.8 2.0 1.6 1 1 0 1 1 1 0 PspA/IM30 family FlaC_arch PF05377.6 KEY70710.1 - 0.038 13.8 0.2 13 5.7 0.0 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) IncA PF04156.9 KEY70710.1 - 0.054 13.0 15.4 4.8 6.7 10.7 2.8 1 1 0 1 1 1 0 IncA protein Gp58 PF07902.6 KEY70710.1 - 0.055 11.6 1.4 0.068 11.3 1.0 1.1 1 0 0 1 1 1 0 gp58-like protein Apolipoprotein PF01442.13 KEY70710.1 - 0.059 12.8 10.4 0.087 12.3 7.2 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Reo_sigmaC PF04582.7 KEY70710.1 - 0.07 12.3 0.2 0.17 11.0 0.1 1.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Rtt102p PF09510.5 KEY70710.1 - 0.076 12.9 0.8 0.18 11.7 0.5 1.7 1 0 0 1 1 1 0 Rtt102p-like transcription regulator protein Filament PF00038.16 KEY70710.1 - 0.08 12.3 14.1 0.18 11.2 3.6 2.1 1 1 1 2 2 2 0 Intermediate filament protein ADIP PF11559.3 KEY70710.1 - 0.11 12.4 14.4 0.27 11.1 2.8 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 KEY70710.1 - 0.16 10.9 15.8 0.038 13.0 5.1 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 CagA PF03507.8 KEY70710.1 - 0.16 11.7 1.1 0.25 11.1 0.3 1.6 2 0 0 2 2 1 0 CagA exotoxin DUF2205 PF10224.4 KEY70710.1 - 0.18 11.4 8.5 2.4 7.7 0.0 3.0 2 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) PilJ PF13675.1 KEY70710.1 - 0.18 12.1 5.1 0.53 10.6 0.8 2.4 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4407 PF14362.1 KEY70710.1 - 0.23 10.3 4.7 0.47 9.3 1.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Zip PF02535.17 KEY70710.1 - 0.3 10.0 2.6 0.29 10.0 1.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Cep57_CLD_2 PF14197.1 KEY70710.1 - 0.32 10.9 21.8 0.63 10.0 0.4 5.2 3 2 1 4 4 4 0 Centrosome localisation domain of PPC89 SpecificRecomb PF10136.4 KEY70710.1 - 0.33 8.9 3.3 0.42 8.5 2.2 1.4 1 1 0 1 1 1 0 Site-specific recombinase DivIC PF04977.10 KEY70710.1 - 0.53 9.7 17.2 2.2 7.7 0.1 4.0 1 1 2 3 3 3 0 Septum formation initiator Fib_alpha PF08702.5 KEY70710.1 - 0.54 10.3 6.9 0.3 11.2 0.6 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Nup54 PF13874.1 KEY70710.1 - 0.79 9.3 7.7 2.5 7.7 2.0 2.6 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Innate_immun PF12782.2 KEY70710.1 - 0.85 8.7 4.0 0.98 8.5 2.8 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family BRE1 PF08647.6 KEY70710.1 - 0.9 9.5 8.1 3.2 7.7 0.9 3.1 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase TSC22 PF01166.13 KEY70710.1 - 1.1 9.3 13.8 5 7.1 1.1 3.7 2 2 1 3 3 3 0 TSC-22/dip/bun family IFP_35_N PF07334.8 KEY70710.1 - 1.1 9.2 4.2 0.6 10.1 0.6 2.3 3 0 0 3 3 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Pox_A_type_inc PF04508.7 KEY70710.1 - 1.7 8.6 5.7 1.8 8.5 0.3 3.5 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat Uso1_p115_C PF04871.8 KEY70710.1 - 2.1 8.2 15.1 6 6.8 4.1 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region MADF_DNA_bdg PF10545.4 KEY70710.1 - 2.1 8.5 12.0 4.9 7.4 4.0 3.0 2 1 0 2 2 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like bZIP_2 PF07716.10 KEY70710.1 - 2.1 8.2 14.6 4.3 7.2 0.9 4.5 3 1 1 4 4 4 0 Basic region leucine zipper Seryl_tRNA_N PF02403.17 KEY70710.1 - 2.3 8.2 7.5 0.54 10.2 1.7 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Microtub_assoc PF07989.6 KEY70710.1 - 3.5 7.5 8.6 1 9.2 1.3 2.8 2 1 1 3 3 3 0 Microtubule associated Atg14 PF10186.4 KEY70710.1 - 3.6 6.4 12.2 8.6 5.1 7.6 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIVA PF05103.8 KEY70710.1 - 3.8 7.5 12.4 6.7 6.7 0.2 3.4 1 1 3 4 4 4 0 DivIVA protein FtsL PF04999.8 KEY70710.1 - 3.9 7.2 6.7 0.42 10.3 0.7 2.4 2 1 1 3 3 2 0 Cell division protein FtsL DUF641 PF04859.7 KEY70710.1 - 4 7.2 7.6 1.5 8.5 1.8 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF3166 PF11365.3 KEY70710.1 - 4.6 7.7 8.7 2.1 8.8 2.6 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF3166) Tropomyosin_1 PF12718.2 KEY70710.1 - 7.2 6.4 16.4 0.39 10.5 5.3 2.5 1 1 2 3 3 3 0 Tropomyosin like CCDC-167 PF15188.1 KEY70710.1 - 7.7 6.5 10.3 0.72 9.8 1.8 3.1 2 1 1 3 3 2 0 Coiled-coil domain-containing protein 167 V_ATPase_I PF01496.14 KEY70710.1 - 7.8 4.2 7.8 8.8 4.0 4.8 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family HALZ PF02183.13 KEY70710.1 - 8 6.2 16.6 1.7 8.3 1.0 4.3 3 1 1 4 4 4 0 Homeobox associated leucine zipper Glyco_hydro_35 PF01301.14 KEY70713.1 - 2.6e-58 197.8 0.7 1.3e-57 195.6 0.5 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 KEY70713.1 - 1.9e-39 134.3 0.4 1.8e-19 70.0 0.0 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 KEY70713.1 - 1.5e-37 128.6 2.4 3.3e-37 127.5 1.6 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 KEY70713.1 - 1.2e-16 59.8 0.1 5.9e-16 57.6 0.0 2.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Fungal_trans PF04082.13 KEY70714.1 - 6.1e-12 44.9 0.0 1.2e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY70714.1 - 4.3e-06 26.5 16.9 7.2e-06 25.8 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2967 PF11179.3 KEY70714.1 - 0.032 13.7 3.5 0.057 12.8 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Sugar_tr PF00083.19 KEY70715.1 - 1.8e-66 224.6 23.3 2.2e-66 224.3 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY70715.1 - 8e-20 70.8 18.4 8e-20 70.8 12.7 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KEY70715.1 - 0.0013 17.0 1.2 0.0013 17.0 0.9 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4131 PF13567.1 KEY70715.1 - 0.29 10.5 3.6 1.6 8.0 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Glyco_hydro_88 PF07470.8 KEY70716.1 - 2.4e-16 59.7 0.5 3.3e-16 59.2 0.3 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Alginate_lyase PF05426.7 KEY70717.1 - 3.1e-05 23.4 0.2 4.9e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 Alginate lyase DUF2461 PF09365.5 KEY70718.1 - 8.9e-06 25.2 0.0 1.1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Exo_endo_phos PF03372.18 KEY70719.1 - 3.2e-12 46.9 0.2 4.8e-12 46.3 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HSP70 PF00012.15 KEY70720.1 - 6.7e-270 896.1 12.8 7.6e-270 896.0 8.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KEY70720.1 - 3.5e-19 68.5 1.4 1.4e-17 63.2 0.2 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 KEY70720.1 - 0.0069 15.5 2.6 0.044 12.8 0.1 2.8 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase FtsA PF14450.1 KEY70720.1 - 0.12 12.2 8.0 4.4 7.1 0.1 3.8 3 1 0 3 3 3 0 Cell division protein FtsA FGGY_C PF02782.11 KEY70720.1 - 0.15 11.6 0.0 0.92 9.0 0.0 2.2 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain GTP_EFTU PF00009.22 KEY70721.1 - 7.6e-49 165.7 0.0 2.9e-48 163.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 KEY70721.1 - 8.6e-21 73.8 2.9 1.6e-20 72.9 2.0 1.4 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.12 KEY70721.1 - 9.4e-10 38.5 0.0 9.4e-09 35.3 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 KEY70721.1 - 8.9e-08 32.0 0.0 2.2e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 KEY70721.1 - 1.9e-07 31.0 0.1 6.1e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KEY70721.1 - 4.7e-05 22.9 0.0 0.00013 21.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 KEY70721.1 - 0.001 19.5 0.5 0.018 15.5 0.0 2.7 2 1 0 2 2 2 1 Miro-like protein Septin PF00735.13 KEY70721.1 - 0.073 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Septin Cpn60_TCP1 PF00118.19 KEY70722.1 - 1.7e-148 495.2 3.7 2.1e-148 494.9 2.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RTA1 PF04479.8 KEY70723.1 - 4e-33 114.8 10.2 1.8e-20 73.4 2.3 2.1 2 0 0 2 2 2 2 RTA1 like protein DUF751 PF05421.6 KEY70723.1 - 0.072 13.3 0.5 0.072 13.3 0.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF751) DUF2651 PF10852.3 KEY70723.1 - 0.83 10.0 7.3 0.13 12.6 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2651) DUF4271 PF14093.1 KEY70723.1 - 7.3 6.2 15.4 2.1 7.9 4.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4271) zf-CHY PF05495.7 KEY70724.1 - 4.1e-17 62.1 25.5 2.3e-16 59.7 9.8 3.3 3 0 0 3 3 3 2 CHY zinc finger Mu-like_Com PF10122.4 KEY70724.1 - 6.4e-05 21.9 0.4 6.4e-05 21.9 0.3 2.4 2 0 0 2 2 2 1 Mu-like prophage protein Com RWD PF05773.17 KEY70724.1 - 0.00011 22.0 0.2 0.00058 19.7 0.0 2.2 2 0 0 2 2 2 1 RWD domain DZR PF12773.2 KEY70724.1 - 8.5 6.2 19.6 16 5.4 0.7 3.7 3 1 0 3 3 3 0 Double zinc ribbon DUF3295 PF11702.3 KEY70727.1 - 1.7e-128 429.8 31.4 2.7e-128 429.1 21.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 KEY70727.1 - 1.4e-12 46.9 0.9 3.7e-12 45.6 0.6 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) AMP-binding PF00501.23 KEY70729.1 - 2.9e-78 263.1 0.0 4.1e-78 262.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme UCH PF00443.24 KEY70730.1 - 9e-44 149.5 1.0 1.4e-43 148.9 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEY70730.1 - 1.3e-21 77.3 1.1 1.9e-21 76.7 0.8 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 KEY70730.1 - 5.5e-10 39.5 0.0 1.2e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain USP8_dimer PF08969.6 KEY70730.1 - 0.0013 18.7 0.0 0.004 17.0 0.0 1.8 1 0 0 1 1 1 1 USP8 dimerisation domain VHS PF00790.14 KEY70731.1 - 9.4e-41 138.7 3.2 2.1e-40 137.6 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 KEY70731.1 - 3.7e-15 55.5 4.5 6.1e-15 54.8 3.1 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 KEY70731.1 - 0.00013 21.2 14.4 0.0086 15.5 0.5 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif zf-DHHC PF01529.15 KEY70731.1 - 0.0015 17.9 1.0 0.0031 16.9 0.7 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ribosomal_S30AE PF02482.14 KEY70731.1 - 0.065 13.6 1.0 0.21 12.0 0.7 1.9 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein C1_1 PF00130.17 KEY70731.1 - 0.24 11.1 7.1 0.44 10.3 4.9 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Peptidase_M4_C PF02868.10 KEY70732.1 - 1.8e-30 105.8 0.0 5.2e-30 104.3 0.0 1.7 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.13 KEY70732.1 - 6.5e-28 97.7 0.1 9.1e-28 97.2 0.1 1.2 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Peptidase_M13 PF01431.16 KEY70732.1 - 0.0022 17.1 0.1 0.0049 16.0 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M36 PF02128.10 KEY70732.1 - 0.012 14.5 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 0 Fungalysin metallopeptidase (M36) DUF4649 PF15507.1 KEY70732.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4649) Glyco_hydro_16 PF00722.16 KEY70733.1 - 6.5e-42 142.9 1.0 1.3e-41 141.9 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Mucin PF01456.12 KEY70733.1 - 7.2 6.3 25.1 17 5.2 17.4 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF572 PF04502.8 KEY70734.1 - 1.2e-52 179.1 0.0 2e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) SIR2 PF02146.12 KEY70734.1 - 9.5e-33 113.4 0.0 2e-32 112.3 0.0 1.6 1 1 0 1 1 1 1 Sir2 family Glyco_transf_28 PF03033.15 KEY70734.1 - 0.06 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain FlgN PF05130.7 KEY70734.1 - 0.69 10.1 3.4 10 6.3 1.8 2.2 2 0 0 2 2 2 0 FlgN protein UQ_con PF00179.21 KEY70736.1 - 2.7e-35 120.8 0.0 3.9e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pantoate_transf PF02548.10 KEY70737.1 - 2.4e-104 348.0 0.5 3e-104 347.7 0.4 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 KEY70737.1 - 2.7e-10 39.8 0.1 4.9e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase APG12 PF04110.8 KEY70738.1 - 2e-26 92.0 0.0 2.5e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 KEY70738.1 - 0.0017 18.2 0.0 0.002 18.0 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Lyase_aromatic PF00221.14 KEY70739.1 - 5.1e-152 506.6 5.7 6.7e-152 506.2 3.9 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Dfp1_Him1_M PF08630.5 KEY70740.1 - 5e-41 139.3 1.4 5.2e-41 139.3 0.1 1.7 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.7 KEY70740.1 - 7e-23 80.0 0.9 1.6e-22 78.9 0.6 1.6 1 0 0 1 1 1 1 DBF zinc finger Peptidase_M24 PF00557.19 KEY70741.1 - 5.3e-52 176.4 0.0 7.1e-52 175.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KEY70741.1 - 3.2e-29 101.0 0.0 6e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain NTP_transferase PF00483.18 KEY70742.1 - 1.4e-48 165.3 0.0 3.5e-48 164.0 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 KEY70742.1 - 2.6e-17 61.4 17.5 1.3e-10 40.2 2.3 4.0 2 2 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KEY70742.1 - 1.5e-10 41.4 0.0 2.1e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KEY70742.1 - 7.1e-08 31.8 8.4 1.3e-06 27.7 2.5 3.3 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 KEY70742.1 - 0.005 16.4 0.0 0.0095 15.5 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase FGGY_C PF02782.11 KEY70743.1 - 3.3e-67 225.9 2.1 5.3e-67 225.2 1.4 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KEY70743.1 - 9.1e-63 211.8 0.0 1.3e-62 211.3 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MAP65_ASE1 PF03999.7 KEY70744.1 - 0.62 8.5 4.2 0.92 8.0 2.9 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) His_Phos_1 PF00300.17 KEY70745.1 - 1.4e-18 67.4 0.1 8.5e-18 64.9 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) ADH_N PF08240.7 KEY70746.1 - 9.3e-22 76.8 5.8 1.5e-21 76.2 4.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY70746.1 - 4.5e-20 71.5 0.0 6.9e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY70746.1 - 9.1e-08 33.0 0.0 1.9e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KEY70746.1 - 0.0086 15.2 0.2 0.014 14.5 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 KEY70746.1 - 0.033 14.1 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Sec63 PF02889.11 KEY70747.1 - 1.4e-28 100.0 0.0 1.5e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Sec63 Brl domain HHH_5 PF14520.1 KEY70747.1 - 0.041 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH PF00633.18 KEY70747.1 - 0.17 11.6 1.3 1.6 8.5 0.0 2.7 3 0 0 3 3 3 0 Helix-hairpin-helix motif DUF3649 PF12365.3 KEY70748.1 - 0.19 11.2 2.9 0.5 9.9 2.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) Band_7 PF01145.20 KEY70749.1 - 1.7e-31 109.5 0.3 3.2e-31 108.6 0.2 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KEY70749.1 - 0.044 13.2 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family UQ_con PF00179.21 KEY70750.1 - 7e-18 64.4 0.0 7.8e-18 64.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 KEY70750.1 - 0.0019 17.8 0.0 0.0023 17.5 0.0 1.1 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 KEY70750.1 - 0.0065 16.3 0.0 0.0067 16.3 0.0 1.2 1 0 0 1 1 1 1 RWD domain Flavoprotein PF02441.14 KEY70752.1 - 6.2e-16 58.2 0.0 1.2e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Flavoprotein Sec7_N PF12783.2 KEY70753.1 - 3.7e-36 124.0 1.3 1.6e-34 118.7 0.0 3.3 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KEY70753.1 - 9.1e-06 25.1 0.4 0.00065 19.1 0.0 4.0 4 1 1 5 5 5 1 Domain of unknown function (DUF1981) FtsJ PF01728.14 KEY70754.1 - 1.5e-59 201.0 0.0 1.9e-59 200.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Acetyltransf_1 PF00583.19 KEY70755.1 - 6.5e-08 32.5 0.0 1.2e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEY70755.1 - 5.4e-05 23.2 0.0 9.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEY70755.1 - 0.00054 19.8 0.1 0.001 18.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEY70755.1 - 0.00077 19.1 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KEY70755.1 - 0.087 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Homoserine_dh PF00742.14 KEY70756.1 - 0.097 12.3 2.1 0.13 11.9 1.5 1.2 1 0 0 1 1 1 0 Homoserine dehydrogenase Herpes_BLLF1 PF05109.8 KEY70756.1 - 1.4 6.7 22.3 1.5 6.6 15.4 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF4078 PF13300.1 KEY70757.1 - 6.8e-29 99.8 19.2 6.8e-29 99.8 13.3 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) bZIP_1 PF00170.16 KEY70757.1 - 9.1e-12 44.7 3.8 9.1e-12 44.7 2.7 2.8 3 0 0 3 3 3 1 bZIP transcription factor TTKRSYEDQ PF10212.4 KEY70757.1 - 0.048 12.5 0.2 0.097 11.5 0.1 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Homoserine_dh PF00742.14 KEY70758.1 - 1.4e-52 177.9 0.0 1.8e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 KEY70758.1 - 1.3e-18 67.4 0.0 2.2e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Methyltransf_4 PF02390.12 KEY70759.1 - 2e-52 177.1 0.0 2.5e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KEY70759.1 - 4.7e-05 23.9 0.0 7.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY70759.1 - 0.00014 21.8 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY70759.1 - 0.0072 16.6 0.1 0.02 15.2 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain FmrO PF07091.6 KEY70759.1 - 0.0078 15.2 0.0 0.028 13.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_31 PF13847.1 KEY70759.1 - 0.014 14.9 0.0 0.018 14.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KEY70759.1 - 0.051 14.0 0.0 0.17 12.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KEY70759.1 - 0.08 12.6 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KEY70759.1 - 0.087 13.3 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KEY70759.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.1 KEY70759.1 - 0.17 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RRM_1 PF00076.17 KEY70760.1 - 3.2e-25 87.5 0.0 7.1e-12 44.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY70760.1 - 1.7e-20 72.7 0.0 1.9e-09 37.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY70760.1 - 5.9e-15 54.8 0.0 3e-06 26.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PEX11 PF05648.9 KEY70761.1 - 6.8e-67 225.0 0.2 7.6e-67 224.8 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) FBPase PF00316.15 KEY70762.1 - 1.7e-122 408.2 0.0 2e-122 408.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase CIA30 PF08547.7 KEY70763.1 - 1.3e-32 112.8 0.0 1.7e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) bZIP_1 PF00170.16 KEY70764.1 - 0.0009 19.1 11.6 0.001 18.9 7.6 1.4 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KEY70764.1 - 0.0022 17.8 7.8 0.0041 16.8 5.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Glyco_hydro_35 PF01301.14 KEY70764.1 - 1.3 8.3 4.5 0.32 10.3 0.5 1.7 2 0 0 2 2 2 0 Glycosyl hydrolases family 35 SEEEED PF14797.1 KEY70764.1 - 2.3 8.3 12.8 4 7.5 8.9 1.4 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex bZIP_Maf PF03131.12 KEY70764.1 - 4.4 7.6 10.0 5.4 7.3 6.5 1.4 1 1 0 1 1 1 0 bZIP Maf transcription factor DUF4568 PF15132.1 KEY70765.1 - 0.05 12.7 0.1 0.063 12.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) GST_C PF00043.20 KEY70767.1 - 7.6e-09 35.4 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KEY70767.1 - 8.6e-08 32.2 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KEY70767.1 - 9.1e-08 32.2 0.0 1.5e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEY70767.1 - 8.2e-07 28.8 0.0 2.5e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KEY70767.1 - 9.8e-07 28.6 0.0 1.8e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KEY70767.1 - 0.00065 20.1 0.0 0.001 19.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PXA PF02194.10 KEY70768.1 - 8e-51 172.2 0.1 8e-51 172.2 0.1 3.2 5 0 0 5 5 5 1 PXA domain Nexin_C PF08628.7 KEY70768.1 - 1.2e-29 102.6 1.1 4.6e-29 100.7 0.1 2.6 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.19 KEY70768.1 - 7.9e-21 73.9 1.1 2.9e-20 72.1 0.7 2.1 2 0 0 2 2 2 1 PX domain RGS PF00615.14 KEY70768.1 - 2.6e-13 50.1 0.1 9.4e-13 48.3 0.1 2.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain Rcd1 PF04078.8 KEY70769.1 - 5.2e-131 435.2 3.9 7.1e-131 434.8 2.7 1.2 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Herpes_UL4 PF03277.8 KEY70769.1 - 0.12 11.5 3.7 0.45 9.7 2.7 1.9 2 0 0 2 2 2 0 Herpesvirus UL4 family Maf1 PF09174.5 KEY70769.1 - 0.16 11.7 3.7 0.29 10.9 2.5 1.3 1 0 0 1 1 1 0 Maf1 regulator TFIIA PF03153.8 KEY70769.1 - 0.44 10.3 23.3 0.61 9.9 16.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med13_N PF11597.3 KEY70769.1 - 0.6 8.7 8.9 0.81 8.2 6.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Bul1_N PF04425.7 KEY70769.1 - 1.7 7.1 9.1 2.7 6.4 6.3 1.3 1 0 0 1 1 1 0 Bul1 N terminus DOR PF14839.1 KEY70769.1 - 2.4 7.8 17.2 3.8 7.1 11.9 1.3 1 0 0 1 1 1 0 DOR family Miff PF05644.6 KEY70769.1 - 2.6 7.5 10.0 4.1 6.9 6.9 1.2 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Suf PF05843.9 KEY70769.1 - 4 7.0 10.0 6.1 6.4 6.9 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.3 KEY70769.1 - 4.9 6.4 8.6 9.7 5.4 6.0 1.5 1 0 0 1 1 1 0 Spt20 family PAT1 PF09770.4 KEY70769.1 - 5.1 5.2 28.7 6 4.9 19.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UPF0560 PF10577.4 KEY70769.1 - 8.7 4.4 14.5 12 4.0 10.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Pkinase PF00069.20 KEY70770.1 - 2.1e-75 253.2 1.1 2.4e-75 253.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY70770.1 - 1.8e-39 135.3 0.0 4.5e-39 134.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 KEY70770.1 - 4.5e-18 64.4 0.1 7.5e-18 63.7 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 KEY70770.1 - 8e-06 25.0 0.0 1.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KEY70770.1 - 0.0001 21.3 0.0 0.00017 20.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KEY70770.1 - 0.035 13.4 0.0 0.035 13.4 0.0 2.4 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL DUF1604 PF07713.8 KEY70771.1 - 3e-38 129.4 1.6 9.2e-38 127.9 1.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.18 KEY70771.1 - 2.2e-05 24.1 1.6 2.2e-05 24.1 1.1 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 KEY70771.1 - 0.0012 18.6 0.4 0.0012 18.6 0.3 3.2 4 0 0 4 4 4 1 DExH-box splicing factor binding site GSDH PF07995.6 KEY70772.1 - 7.5e-09 35.1 0.3 1.7e-08 33.9 0.2 1.6 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase SGL PF08450.7 KEY70772.1 - 0.003 16.9 1.3 0.63 9.3 0.1 2.9 2 1 1 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 KEY70772.1 - 0.0099 15.7 0.1 14 5.8 0.0 3.7 3 1 0 3 3 3 2 NHL repeat Reg_prop PF07494.6 KEY70772.1 - 0.06 13.3 0.1 2.4 8.4 0.0 3.2 3 0 0 3 3 3 0 Two component regulator propeller WD40 PF00400.27 KEY70773.1 - 2.6e-51 169.7 15.6 5.8e-11 41.8 0.2 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KEY70773.1 - 1.4e-08 34.6 10.0 0.02 14.5 0.1 4.4 3 1 1 4 4 4 3 Transcription factor IIIC subunit delta N-term Herpes_US9 PF06072.6 KEY70775.1 - 0.082 12.7 0.6 0.18 11.6 0.4 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 BCS1_N PF08740.6 KEY70777.1 - 1e-52 178.4 2.4 1e-52 178.4 1.6 3.0 2 1 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 KEY70777.1 - 2.7e-18 66.4 0.0 1.8e-16 60.5 0.0 2.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEY70777.1 - 1.8e-05 24.8 0.0 4.9e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 KEY70777.1 - 0.00097 18.5 0.0 0.0025 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEY70777.1 - 0.0024 18.6 3.9 0.0088 16.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 KEY70777.1 - 0.0084 15.8 0.1 0.034 13.8 0.0 2.2 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KEY70777.1 - 0.019 13.9 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KEY70777.1 - 0.02 14.6 0.0 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain HMG_CoA_synt_C PF08540.5 KEY70778.1 - 2e-99 332.6 0.1 2.5e-99 332.3 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KEY70778.1 - 3.4e-96 319.7 0.4 4.8e-96 319.2 0.3 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal FAD_binding_4 PF01565.18 KEY70779.1 - 6.5e-15 54.8 0.1 1e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Abhydrolase_3 PF07859.8 KEY70780.1 - 3.7e-40 137.7 0.1 3.7e-40 137.7 0.1 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY70780.1 - 5.5e-05 22.9 0.0 0.00013 21.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KEY70780.1 - 0.0017 17.0 0.0 0.028 13.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Pex14_N PF04695.8 KEY70781.1 - 1.6e-35 122.1 0.1 1.6e-35 122.1 0.1 3.7 3 3 0 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C4H2 PF10146.4 KEY70781.1 - 4e-05 23.7 0.9 6.9e-05 22.9 0.6 1.4 1 0 0 1 1 1 1 Zinc finger-containing protein ERM PF00769.14 KEY70781.1 - 4.5e-05 23.1 4.7 7.1e-05 22.4 3.3 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family IncA PF04156.9 KEY70781.1 - 0.00043 19.9 2.9 0.00069 19.2 2.0 1.3 1 0 0 1 1 1 1 IncA protein HLH PF00010.21 KEY70781.1 - 0.0033 17.0 2.3 2.2 8.0 0.1 3.2 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain AAA_13 PF13166.1 KEY70781.1 - 0.0089 14.5 4.6 0.013 14.0 3.2 1.1 1 0 0 1 1 1 1 AAA domain DUF3584 PF12128.3 KEY70781.1 - 0.01 13.1 13.0 0.014 12.7 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF848 PF05852.6 KEY70781.1 - 0.016 15.0 9.7 0.032 14.1 6.7 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Baculo_PEP_C PF04513.7 KEY70781.1 - 0.028 14.2 3.4 2.5 7.9 0.1 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FH2 PF02181.18 KEY70781.1 - 0.035 13.0 6.6 0.051 12.4 4.6 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain CR6_interact PF10147.4 KEY70781.1 - 0.043 13.1 5.9 0.03 13.6 1.4 2.1 1 1 1 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Prominin PF05478.6 KEY70781.1 - 0.085 10.3 2.9 0.11 9.9 2.0 1.1 1 0 0 1 1 1 0 Prominin IFT57 PF10498.4 KEY70781.1 - 0.32 9.6 11.3 1.1 7.9 8.0 1.6 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 tRNA-synt_His PF13393.1 KEY70781.1 - 0.53 9.2 3.2 1.3 7.9 0.6 2.0 1 1 2 3 3 3 0 Histidyl-tRNA synthetase V-SNARE PF05008.10 KEY70781.1 - 0.54 10.4 9.7 21 5.3 2.0 2.5 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF1043 PF06295.7 KEY70781.1 - 0.76 9.4 3.5 1.3 8.7 2.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) FUSC PF04632.7 KEY70781.1 - 0.94 7.8 2.3 1.3 7.3 1.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMPIT PF07851.8 KEY70781.1 - 1 8.3 2.8 1.3 7.9 1.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein Seryl_tRNA_N PF02403.17 KEY70781.1 - 1.2 9.2 13.6 4.3 7.4 1.9 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Lipoprotein_6 PF01441.14 KEY70781.1 - 1.3 8.8 8.1 2.1 8.1 5.6 1.2 1 0 0 1 1 1 0 Lipoprotein Orbi_VP5 PF00901.12 KEY70781.1 - 1.3 7.1 7.1 2.2 6.3 4.9 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 ADIP PF11559.3 KEY70781.1 - 2.2 8.1 13.1 0.95 9.3 6.6 1.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 KEY70781.1 - 2.5 6.6 12.0 3.6 6.1 8.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 KEY70781.1 - 3.4 5.3 5.9 4.5 4.9 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.7 KEY70781.1 - 5.4 7.3 6.3 12 6.2 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 KEY70781.1 - 5.7 6.7 6.1 12 5.7 4.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Spectrin PF00435.16 KEY70781.1 - 6.2 7.1 12.4 14 6.0 3.6 2.6 2 1 1 3 3 2 0 Spectrin repeat DUF972 PF06156.8 KEY70781.1 - 6.5 7.1 7.5 40 4.6 5.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Sipho_Gp157 PF05565.6 KEY70781.1 - 7.2 6.1 11.6 12 5.4 0.7 2.2 1 1 1 2 2 2 0 Siphovirus Gp157 YkyA PF10368.4 KEY70781.1 - 7.2 5.8 12.4 13 5.0 8.6 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein TPR_MLP1_2 PF07926.7 KEY70781.1 - 7.3 6.3 13.8 1.3 8.7 4.5 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.6 KEY70781.1 - 9.5 6.1 9.6 1.6 8.6 0.5 3.0 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Ndc80_HEC PF03801.8 KEY70782.1 - 2.2e-61 205.9 0.4 2.2e-61 205.9 0.3 1.6 2 0 0 2 2 2 1 HEC/Ndc80p family FliJ PF02050.11 KEY70782.1 - 0.0028 17.6 24.3 0.032 14.3 4.1 3.1 2 1 1 3 3 3 2 Flagellar FliJ protein WASH_WAHD PF11945.3 KEY70782.1 - 0.015 14.6 2.6 0.029 13.6 1.8 1.4 1 0 0 1 1 1 0 WAHD domain of WASH complex Tropomyosin PF00261.15 KEY70782.1 - 0.32 10.0 43.7 0.37 9.8 8.8 3.4 2 1 1 3 3 3 0 Tropomyosin Tropomyosin_1 PF12718.2 KEY70782.1 - 0.55 10.0 46.5 0.19 11.5 8.5 4.4 2 2 2 4 4 4 0 Tropomyosin like ATG16 PF08614.6 KEY70782.1 - 0.8 9.4 32.3 8.1 6.2 7.0 3.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.7 KEY70782.1 - 1.3 8.8 16.0 0.091 12.5 0.4 4.3 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.7 KEY70782.1 - 2.2 8.0 35.0 0.14 11.8 9.4 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Lactamase_B_2 PF12706.2 KEY70784.1 - 1.5e-38 132.3 0.0 1.9e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KEY70784.1 - 8.5e-09 35.3 0.0 1.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KEY70784.1 - 0.00036 20.2 2.4 0.0023 17.6 0.7 2.5 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily BRCT PF00533.21 KEY70784.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain XAP5 PF04921.9 KEY70785.1 - 0.13 11.8 0.7 0.14 11.6 0.5 1.0 1 0 0 1 1 1 0 XAP5, circadian clock regulator PRP1_N PF06424.7 KEY70785.1 - 0.15 12.3 1.8 0.18 12.1 1.2 1.0 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Glyco_hydro_47 PF01532.15 KEY70786.1 - 8e-131 436.7 0.0 9.1e-131 436.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TipAS PF07739.8 KEY70786.1 - 0.037 14.3 0.1 0.081 13.2 0.1 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Rad10 PF03834.9 KEY70787.1 - 2.6e-31 107.1 0.0 4e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 KEY70787.1 - 0.0029 17.7 0.4 0.0062 16.6 0.0 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain Peptidase_S8 PF00082.17 KEY70789.1 - 1.4e-21 76.8 1.1 3.7e-17 62.4 0.5 2.4 1 1 1 2 2 2 2 Subtilase family Ank_2 PF12796.2 KEY70791.1 - 3.4e-74 245.2 3.0 2e-20 72.9 0.1 6.2 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KEY70791.1 - 3.7e-62 203.2 14.9 7.1e-10 38.1 0.0 11.2 11 0 0 11 11 11 10 Ankyrin repeat Ank_4 PF13637.1 KEY70791.1 - 4.5e-61 202.2 8.0 1.1e-15 57.6 0.2 9.1 5 3 4 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY70791.1 - 2.1e-45 148.1 7.9 1.8e-05 24.5 0.1 11.0 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.1 KEY70791.1 - 3.7e-43 144.5 14.3 1.5e-10 40.9 0.5 9.5 3 3 7 10 10 10 10 Ankyrin repeats (many copies) zf-C2H2_4 PF13894.1 KEY70791.1 - 0.23 11.9 1.9 20 5.8 0.0 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger HlyIII PF03006.15 KEY70792.1 - 6.2e-20 71.5 10.1 7.8e-20 71.2 7.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF1158 PF06643.6 KEY70792.1 - 5.5 7.3 6.9 1.2 9.5 2.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1158) Ank PF00023.25 KEY70793.1 - 5.6e-28 95.3 0.5 5.7e-08 32.1 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 KEY70793.1 - 1.7e-26 92.3 0.1 8.1e-13 48.5 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEY70793.1 - 4.2e-22 77.6 6.0 8.1e-09 35.4 0.0 5.5 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY70793.1 - 9.1e-20 68.7 0.3 3.4e-05 23.6 0.0 5.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KEY70793.1 - 3.7e-16 59.1 2.1 1.1e-08 35.3 0.0 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) NACHT PF05729.7 KEY70793.1 - 2.5e-10 40.2 0.0 6.4e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 KEY70793.1 - 7.9e-10 38.0 0.0 1.7e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Phosphorylase superfamily KAP_NTPase PF07693.9 KEY70793.1 - 0.00022 20.3 0.0 0.00042 19.4 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA_19 PF13245.1 KEY70793.1 - 0.0074 16.0 0.0 0.059 13.1 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 KEY70793.1 - 0.046 12.8 0.0 0.28 10.2 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KEY70793.1 - 0.075 12.7 0.0 6 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Shigella_OspC PF06128.6 KEY70793.1 - 0.16 11.4 0.0 5.6 6.3 0.0 2.4 1 1 0 2 2 2 0 Shigella flexneri OspC protein E1-E2_ATPase PF00122.15 KEY70794.1 - 2.1e-47 161.1 5.3 4.1e-47 160.1 3.7 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KEY70794.1 - 2.8e-23 83.4 0.0 5.1e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEY70794.1 - 1e-14 55.1 0.0 2.1e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEY70794.1 - 6.4e-05 22.6 0.2 0.00019 21.1 0.1 1.8 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KEY70794.1 - 0.00053 20.0 0.9 0.0011 19.0 0.0 2.0 2 0 0 2 2 2 1 Heavy-metal-associated domain HAD_2 PF13419.1 KEY70794.1 - 0.17 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase TPR_12 PF13424.1 KEY70795.1 - 0.00079 19.3 0.0 0.0009 19.1 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEY70795.1 - 0.016 14.9 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEY70795.1 - 0.016 15.0 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEY70795.1 - 0.02 14.5 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEY70795.1 - 0.023 14.6 0.1 0.025 14.5 0.0 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.9 KEY70795.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEY70795.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat FAM195 PF14799.1 KEY70797.1 - 0.18 11.6 2.9 0.34 10.7 2.0 1.4 1 0 0 1 1 1 0 FAM195 family Prefoldin_3 PF13758.1 KEY70797.1 - 0.21 11.3 7.0 0.79 9.5 2.9 2.6 1 1 1 2 2 2 0 Prefoldin subunit GAS PF13851.1 KEY70797.1 - 0.22 10.6 23.0 0.034 13.3 2.0 2.9 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 KEY70797.1 - 0.66 8.5 18.6 0.024 13.3 7.1 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF972 PF06156.8 KEY70797.1 - 0.79 10.1 16.9 0.78 10.1 0.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) IncA PF04156.9 KEY70797.1 - 2 7.9 19.3 8.4 5.9 13.4 1.9 1 1 0 1 1 1 0 IncA protein DUF349 PF03993.7 KEY70797.1 - 4.1 7.6 16.3 0.8 9.9 2.7 2.6 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) Occludin_ELL PF07303.8 KEY70797.1 - 5.2 7.8 9.4 23 5.7 4.4 2.6 1 1 1 2 2 2 0 Occludin homology domain Jnk-SapK_ap_N PF09744.4 KEY70797.1 - 5.4 6.9 24.4 13 5.7 1.7 3.1 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DUF883 PF05957.8 KEY70797.1 - 6.1 7.3 9.5 6.1 7.3 2.6 3.3 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.7 KEY70797.1 - 6.7 6.5 8.5 2.9 7.6 0.4 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) FtsL PF04999.8 KEY70797.1 - 8.5 6.1 13.5 3.6 7.3 0.9 3.0 2 2 0 2 2 2 0 Cell division protein FtsL Beta_helix PF13229.1 KEY70803.1 - 0.0052 16.5 0.7 0.0053 16.5 0.5 1.1 1 0 0 1 1 1 1 Right handed beta helix region Epimerase PF01370.16 KEY70804.1 - 3.2e-12 46.3 0.0 5.7e-12 45.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY70804.1 - 2.8e-10 40.5 0.0 7.6e-10 39.0 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEY70804.1 - 2.6e-09 36.1 0.0 4e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KEY70804.1 - 7.8e-08 31.8 0.0 2.4e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 KEY70804.1 - 9.8e-05 21.3 0.2 0.00036 19.5 0.1 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KEY70804.1 - 0.00044 19.2 0.2 0.052 12.4 0.0 2.6 3 0 0 3 3 3 2 Male sterility protein adh_short PF00106.20 KEY70804.1 - 0.0044 16.9 1.9 0.16 11.8 0.2 2.5 2 1 0 2 2 2 1 short chain dehydrogenase Glyoxalase PF00903.20 KEY70805.1 - 8.6e-07 28.9 0.0 1.4e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KEY70805.1 - 1.4e-06 28.8 0.0 2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain DUF3435 PF11917.3 KEY70806.1 - 0.00059 18.6 0.1 0.023 13.4 0.0 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF3435) DUF3632 PF12311.3 KEY70808.1 - 6.8e-24 84.6 2.0 8.9e-24 84.2 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Peptidase_M36 PF02128.10 KEY70810.1 - 0.00012 21.0 0.0 0.00022 20.1 0.0 1.3 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Trypsin PF00089.21 KEY70811.1 - 3.2e-36 124.9 0.3 3.8e-36 124.7 0.2 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 KEY70811.1 - 0.0096 15.8 0.0 0.03 14.2 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain MFS_1 PF07690.11 KEY70812.1 - 2e-12 46.5 28.5 1.1e-11 44.1 5.0 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily M20_dimer PF07687.9 KEY70814.1 - 0.00012 21.8 0.1 0.0003 20.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 KEY70814.1 - 0.0086 15.5 5.1 0.018 14.5 3.6 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 ICL PF00463.16 KEY70815.1 - 6e-44 150.1 0.1 2.9e-41 141.2 0.1 2.0 1 1 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KEY70815.1 - 0.00071 18.8 0.0 0.0017 17.6 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DCA16 PF15349.1 KEY70815.1 - 0.071 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 HLH PF00010.21 KEY70816.1 - 5.8e-10 38.7 0.9 1e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PHO4 PF01384.15 KEY70817.1 - 4.1e-107 357.6 9.6 4.9e-107 357.3 6.7 1.1 1 0 0 1 1 1 1 Phosphate transporter family Arrestin_N PF00339.24 KEY70818.1 - 0.033 14.0 0.0 0.37 10.5 0.0 2.3 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain bZIP_1 PF00170.16 KEY70820.1 - 3.5 7.6 10.4 13 5.8 7.2 1.9 1 1 0 1 1 1 0 bZIP transcription factor SBF PF01758.11 KEY70821.1 - 1.2e-50 171.5 11.7 1.2e-50 171.5 8.1 2.0 3 0 0 3 3 3 1 Sodium Bile acid symporter family DUF3619 PF12279.3 KEY70821.1 - 0.016 15.3 0.2 0.25 11.4 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3619) Rhodanese PF00581.15 KEY70822.1 - 3.2e-08 33.9 0.0 5.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain FSH1 PF03959.8 KEY70823.1 - 3.5e-28 98.5 0.0 4.2e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KEY70823.1 - 2.6e-05 24.0 0.5 4.7e-05 23.1 0.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY70823.1 - 0.00015 21.7 10.9 0.00073 19.4 7.6 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KEY70823.1 - 0.021 14.4 0.6 0.034 13.7 0.4 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Glyco_hydro_47 PF01532.15 KEY70824.1 - 2e-160 534.3 0.0 2.3e-160 534.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GMC_oxred_C PF05199.8 KEY70825.1 - 1.6e-34 119.2 0.0 2.6e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KEY70825.1 - 1.4e-24 86.8 0.0 2.8e-22 79.2 0.0 2.6 2 1 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.1 KEY70825.1 - 0.00029 20.7 0.1 0.00084 19.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEY70825.1 - 0.0022 16.9 0.0 0.0053 15.6 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KEY70825.1 - 0.044 13.6 0.1 0.6 9.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY70825.1 - 0.068 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 KEY70825.1 - 0.08 11.4 0.0 0.13 10.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Peptidase_S8 PF00082.17 KEY70826.1 - 5.4e-47 160.2 3.3 1e-46 159.3 2.3 1.5 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 KEY70826.1 - 6.5e-08 32.9 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 KEY70826.1 - 1.1e-07 31.4 0.0 2.6e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 PA domain Daxx PF03344.10 KEY70827.1 - 0.66 8.3 21.4 0.9 7.9 14.8 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 KEY70827.1 - 2.2 6.1 17.6 3.1 5.7 12.2 1.1 1 0 0 1 1 1 0 CDC45-like protein adh_short PF00106.20 KEY70828.1 - 2.2e-32 112.2 5.7 3e-32 111.8 3.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY70828.1 - 1.6e-13 50.9 0.1 1.9e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY70828.1 - 3.3e-12 46.4 2.8 4.5e-12 46.0 1.9 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KEY70828.1 - 4.8e-06 26.3 0.5 6.6e-06 25.8 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 KEY70828.1 - 6.5e-06 25.7 0.4 1e-05 25.1 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEY70828.1 - 0.00086 18.0 0.2 0.0012 17.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KEY70828.1 - 0.0014 18.7 0.4 0.0047 16.9 0.3 1.9 2 1 0 2 2 1 1 NADH(P)-binding NAD_binding_2 PF03446.10 KEY70828.1 - 0.0022 17.8 0.6 0.0097 15.7 0.2 2.0 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_synt_2 PF02719.10 KEY70828.1 - 0.0024 16.8 0.0 0.0029 16.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.14 KEY70828.1 - 0.0056 15.8 0.1 0.009 15.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KEY70828.1 - 0.011 16.1 0.2 0.026 14.9 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.14 KEY70828.1 - 0.011 14.7 0.1 0.052 12.6 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.18 KEY70828.1 - 0.012 15.4 0.1 0.023 14.4 0.1 1.6 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 KEY70828.1 - 0.017 14.0 0.1 0.029 13.2 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DapB_N PF01113.15 KEY70828.1 - 0.023 14.6 1.5 0.17 11.8 1.0 2.3 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DFP PF04127.10 KEY70828.1 - 0.026 14.1 0.3 0.043 13.4 0.2 1.4 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_binding_4 PF07993.7 KEY70828.1 - 0.039 12.8 0.7 0.087 11.7 0.5 1.7 1 1 0 1 1 1 0 Male sterility protein NmrA PF05368.8 KEY70828.1 - 0.065 12.4 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family TrkA_N PF02254.13 KEY70828.1 - 0.069 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Eno-Rase_NADH_b PF12242.3 KEY70828.1 - 0.079 12.7 2.0 0.12 12.2 0.2 2.1 2 1 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CLCA_N PF08434.6 KEY70828.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel MLIP PF15274.1 KEY70829.1 - 0.16 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Muscular LMNA-interacting protein HET PF06985.6 KEY70830.1 - 2.3e-23 82.8 0.0 4e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 KEY70831.1 - 8.4e-30 103.7 0.3 1e-28 100.2 0.2 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RuvB_N PF05496.7 KEY70831.1 - 0.14 11.2 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Abhydrolase_6 PF12697.2 KEY70832.1 - 4.3e-22 79.1 0.1 5.7e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY70832.1 - 8.1e-11 41.8 0.0 1.2e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY70832.1 - 0.00085 18.9 0.2 0.036 13.6 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold adh_short PF00106.20 KEY70834.1 - 4e-17 62.6 0.0 8.7e-17 61.5 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY70834.1 - 1.7e-07 31.0 0.0 2.9e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY70834.1 - 4.3e-06 26.3 0.2 7.8e-06 25.4 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY70834.1 - 5.2e-06 26.5 0.0 8.2e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KEY70834.1 - 0.003 16.5 0.0 0.0044 15.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 KEY70834.1 - 0.0096 15.7 0.0 0.025 14.3 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 KEY70834.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.12 KEY70834.1 - 0.065 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Arginosuc_synth PF00764.14 KEY70835.1 - 2.6e-30 105.7 0.1 9.7e-15 54.4 0.0 3.0 2 1 1 3 3 3 3 Arginosuccinate synthase MFS_1 PF07690.11 KEY70836.1 - 4.6e-42 143.9 24.7 4.6e-42 143.9 17.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1996 PF09362.5 KEY70837.1 - 1.9e-89 299.3 0.1 2.4e-89 299.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.13 KEY70837.1 - 1.4e-14 53.4 7.0 1.4e-14 53.4 4.9 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Mpv17_PMP22 PF04117.7 KEY70838.1 - 1.3e-15 56.7 0.9 2.4e-15 55.9 0.6 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family 3Beta_HSD PF01073.14 KEY70839.1 - 5.3e-22 77.8 0.0 8.1e-21 73.9 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KEY70839.1 - 7.2e-14 51.7 0.0 1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KEY70839.1 - 5.3e-08 32.1 0.0 1.7e-06 27.1 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KEY70839.1 - 1.3e-05 25.3 0.0 0.0001 22.3 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KEY70839.1 - 6.3e-05 22.7 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KEY70839.1 - 0.00011 22.1 0.1 0.0017 18.3 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KEY70839.1 - 0.00011 21.1 0.0 0.00021 20.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Yip1 PF04893.12 KEY70840.1 - 0.029 13.8 0.0 0.035 13.6 0.0 1.1 1 0 0 1 1 1 0 Yip1 domain VSP PF03302.8 KEY70840.1 - 0.062 11.9 0.4 0.083 11.5 0.3 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein FTR1 PF03239.9 KEY70840.1 - 0.14 11.0 0.1 0.19 10.6 0.1 1.1 1 0 0 1 1 1 0 Iron permease FTR1 family SelP_N PF04592.9 KEY70840.1 - 1.3 8.3 4.1 2 7.7 2.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HET PF06985.6 KEY70843.1 - 3.4e-37 127.7 0.1 4.6e-37 127.2 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Luteo_Vpg PF01659.11 KEY70843.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein PGAP1 PF07819.8 KEY70844.1 - 2.6e-88 295.4 0.0 3.9e-88 294.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KEY70844.1 - 3.6e-06 26.7 0.0 7.2e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY70844.1 - 1.3e-05 25.2 0.2 1.3e-05 25.2 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY70844.1 - 0.0031 17.1 0.0 0.0097 15.4 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.9 KEY70844.1 - 0.027 13.7 0.1 0.046 13.0 0.1 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Esterase PF00756.15 KEY70844.1 - 0.13 11.6 0.0 0.31 10.4 0.0 1.5 2 0 0 2 2 2 0 Putative esterase COesterase PF00135.23 KEY70844.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family LCAT PF02450.10 KEY70844.1 - 0.14 11.1 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase MFS_1 PF07690.11 KEY70845.1 - 1.4e-16 60.1 37.3 7.8e-11 41.2 15.9 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.8 KEY70845.1 - 2.2e-13 50.0 2.9 2.2e-13 50.0 2.0 2.3 2 0 0 2 2 2 1 Nodulin-like Serinc PF03348.10 KEY70846.1 - 7.9e-165 548.7 7.1 1e-164 548.3 4.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Cys_Met_Meta_PP PF01053.15 KEY70847.1 - 1.1e-137 458.4 0.0 1.3e-137 458.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KEY70847.1 - 1.3e-07 30.9 0.0 2.1e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KEY70847.1 - 7.1e-07 28.2 0.0 1.8e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KEY70847.1 - 3.2e-06 26.4 0.0 6.3e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.6 KEY70847.1 - 3.9e-05 22.1 0.1 0.00011 20.5 0.1 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 KEY70847.1 - 6.8e-05 21.7 0.1 0.00016 20.5 0.0 1.5 1 1 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 KEY70847.1 - 0.0011 18.1 0.1 0.0024 17.0 0.1 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase DEDD_Tnp_IS110 PF01548.12 KEY70847.1 - 0.059 13.0 0.0 28 4.3 0.0 3.1 3 0 0 3 3 3 0 Transposase AAA PF00004.24 KEY70848.1 - 2.9e-38 131.0 0.0 4.7e-38 130.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEY70848.1 - 1.2e-06 28.6 0.2 0.00016 21.7 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KEY70848.1 - 2.1e-06 27.9 0.2 0.00033 20.8 0.0 3.3 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.1 KEY70848.1 - 2.2e-06 27.5 0.0 5.6e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEY70848.1 - 9.7e-06 25.3 0.4 7.6e-05 22.4 0.1 2.7 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KEY70848.1 - 2.6e-05 23.3 0.0 7e-05 21.9 0.0 1.7 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KEY70848.1 - 3.9e-05 24.4 0.2 0.00013 22.7 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.9 KEY70848.1 - 5.2e-05 23.2 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 KEY70848.1 - 0.00034 20.0 0.3 0.029 13.7 0.1 2.7 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KEY70848.1 - 0.00038 19.9 0.0 0.00068 19.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KEY70848.1 - 0.00072 18.7 0.0 0.0013 17.9 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KEY70848.1 - 0.00079 18.5 0.0 0.002 17.2 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 KEY70848.1 - 0.00087 19.1 0.8 0.0016 18.2 0.0 2.0 2 1 0 2 2 1 1 AAA domain Sigma54_activ_2 PF14532.1 KEY70848.1 - 0.00091 19.2 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.17 KEY70848.1 - 0.0011 19.1 0.0 0.0028 17.7 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 KEY70848.1 - 0.0013 19.0 0.0 0.0053 17.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KEY70848.1 - 0.0025 17.7 0.2 0.0071 16.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 KEY70848.1 - 0.0039 16.8 0.0 0.0086 15.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.1 KEY70848.1 - 0.0062 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KEY70848.1 - 0.0069 15.3 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Oxidored_nitro PF00148.14 KEY70848.1 - 0.0085 14.7 0.0 0.59 8.7 0.0 2.1 2 0 0 2 2 2 1 Nitrogenase component 1 type Oxidoreductase Sigma54_activat PF00158.21 KEY70848.1 - 0.011 15.2 0.0 0.026 14.0 0.0 1.5 2 0 0 2 2 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 KEY70848.1 - 0.018 15.3 0.0 0.059 13.6 0.0 2.0 1 1 0 1 1 1 0 ABC transporter Guanylate_kin PF00625.16 KEY70848.1 - 0.02 14.3 0.0 0.23 10.8 0.0 2.5 2 1 1 3 3 3 0 Guanylate kinase AAA_19 PF13245.1 KEY70848.1 - 0.023 14.4 0.0 0.023 14.4 0.0 2.1 3 0 0 3 3 1 0 Part of AAA domain Arch_ATPase PF01637.13 KEY70848.1 - 0.025 14.2 0.2 0.24 11.0 0.0 2.3 2 1 1 3 3 2 0 Archaeal ATPase Rad17 PF03215.10 KEY70848.1 - 0.029 13.0 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Parvo_NS1 PF01057.12 KEY70848.1 - 0.035 12.9 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KEY70848.1 - 0.085 11.6 0.0 0.29 9.9 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain TIP49 PF06068.8 KEY70848.1 - 0.091 11.4 0.0 0.16 10.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus Bac_DnaA PF00308.13 KEY70848.1 - 0.094 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein SKI PF01202.17 KEY70848.1 - 0.094 12.5 0.8 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 Shikimate kinase UPF0079 PF02367.12 KEY70848.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 KEY70848.1 - 0.11 11.9 0.5 1.8 7.9 0.0 2.7 3 1 0 3 3 3 0 AAA-like domain SMC_N PF02463.14 KEY70848.1 - 0.12 11.6 0.0 12 5.0 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_3 PF07726.6 KEY70848.1 - 0.15 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 KEY70848.1 - 0.18 10.7 0.1 0.62 9.0 0.0 1.8 1 1 1 2 2 2 0 KAP family P-loop domain Csm1 PF12539.3 KEY70849.1 - 6e-27 93.9 0.0 1.3e-26 92.8 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 PspA_IM30 PF04012.7 KEY70849.1 - 0.0029 17.0 12.8 0.0029 17.0 8.9 1.7 2 0 0 2 2 2 1 PspA/IM30 family FlaC_arch PF05377.6 KEY70849.1 - 0.035 14.0 0.6 0.075 12.9 0.0 1.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Cortex-I_coil PF09304.5 KEY70849.1 - 0.15 12.1 10.5 0.12 12.4 5.6 2.0 1 1 1 2 2 2 0 Cortexillin I, coiled coil IncA PF04156.9 KEY70849.1 - 0.42 10.1 12.6 0.8 9.2 2.6 2.3 1 1 1 2 2 2 0 IncA protein Spc7 PF08317.6 KEY70849.1 - 1.7 7.2 10.0 2.4 6.7 6.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PEP-utilisers_N PF05524.8 KEY70849.1 - 2.3 8.0 12.2 0.19 11.5 2.5 2.5 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF4472 PF14739.1 KEY70849.1 - 3.2 8.2 9.4 0.49 10.8 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) ADIP PF11559.3 KEY70849.1 - 5.1 6.9 13.5 8.5 6.2 7.6 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding PigN PF04987.9 KEY70850.1 - 4.6e-155 516.6 31.3 5.9e-155 516.2 21.7 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 KEY70850.1 - 8.3e-10 38.5 1.1 1.2e-07 31.3 0.8 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KEY70850.1 - 3e-08 33.2 1.6 3.1e-08 33.1 0.4 1.5 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 KEY70850.1 - 0.00039 19.8 0.0 0.00079 18.8 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily SPC12 PF06645.8 KEY70850.1 - 1.3 8.8 9.6 0.1 12.4 1.3 3.1 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Fungal_trans PF04082.13 KEY70851.1 - 1.9e-37 128.5 0.0 5e-37 127.1 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY70851.1 - 0.00059 19.6 1.8 0.00099 18.9 1.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LysM PF01476.15 KEY70852.1 - 0.058 13.2 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 LysM domain Arv1 PF04161.8 KEY70853.1 - 3.2e-34 118.6 1.5 2.3e-18 66.8 0.1 2.4 1 1 1 2 2 2 2 Arv1-like family ATP_synt_H PF05493.8 KEY70854.1 - 2.1e-26 91.7 1.4 2.3e-26 91.6 1.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Polysacc_synt_C PF14667.1 KEY70854.1 - 0.019 14.7 0.3 0.023 14.4 0.2 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain 7TM-7TMR_HD PF07698.6 KEY70854.1 - 0.054 12.9 0.8 0.06 12.7 0.6 1.1 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase Git3 PF11710.3 KEY70854.1 - 0.059 12.9 0.1 0.06 12.9 0.1 1.0 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Glucos_trans_II PF14264.1 KEY70854.1 - 0.067 12.1 1.1 0.077 11.9 0.8 1.0 1 0 0 1 1 1 0 Glucosyl transferase GtrII YfhO PF09586.5 KEY70854.1 - 0.17 9.8 0.3 0.18 9.7 0.2 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO YesK PF14150.1 KEY70854.1 - 0.2 11.7 2.8 0.25 11.4 2.0 1.1 1 0 0 1 1 1 0 YesK-like protein TauD PF02668.11 KEY70856.1 - 5e-56 190.2 0.5 6e-56 189.9 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NAD_binding_2 PF03446.10 KEY70857.1 - 2.3e-28 99.0 0.0 3.8e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KEY70857.1 - 3.9e-09 36.6 0.1 9.3e-09 35.3 0.1 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KEY70857.1 - 1.8e-08 34.7 0.0 8.8e-08 32.4 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KEY70857.1 - 6.5e-06 26.2 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 KEY70857.1 - 0.024 13.7 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF619 PF04768.8 KEY70858.1 - 1.3e-53 180.9 0.0 3e-53 179.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF619) BAR_2 PF10455.4 KEY70859.1 - 6e-61 205.8 0.1 1.2e-60 204.8 0.1 1.5 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KEY70859.1 - 7.4e-21 74.7 1.3 1.4e-19 70.5 0.9 2.2 1 1 0 1 1 1 1 BAR domain ETC_C1_NDUFA5 PF04716.9 KEY70859.1 - 1.6e-20 72.4 0.2 4.8e-20 70.8 0.2 1.9 1 0 0 1 1 1 1 ETC complex I subunit conserved region RNA_pol_I_TF PF04090.7 KEY70860.1 - 0.013 14.7 0.0 0.36 10.0 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase I specific initiation factor Nucleo_P87 PF07267.6 KEY70860.1 - 0.2 10.3 2.5 0.12 11.0 0.2 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 WD40 PF00400.27 KEY70861.1 - 5.6e-15 54.5 24.1 5.1e-06 26.1 0.1 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat PAS_3 PF08447.6 KEY70862.1 - 4.6e-11 42.6 0.0 1.4e-08 34.6 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 KEY70862.1 - 2.6e-10 40.5 0.0 4.5e-06 26.9 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.1 KEY70862.1 - 1.7e-09 37.5 0.0 2.3e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 KEY70862.1 - 2.4e-09 36.9 0.0 2.1e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 KEY70862.1 - 0.00032 20.7 0.0 0.002 18.1 0.0 2.3 2 0 0 2 2 2 1 PAS fold Ebola_NP PF05505.7 KEY70862.1 - 3.7 5.5 6.1 5 5.0 4.3 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein APH PF01636.18 KEY70863.1 - 7e-06 25.9 1.7 1.1e-05 25.2 1.2 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Yip1 PF04893.12 KEY70864.1 - 6e-13 48.6 14.5 9.5e-13 48.0 10.0 1.3 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 KEY70864.1 - 0.011 15.4 8.0 0.018 14.7 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Ran_BP1 PF00638.13 KEY70865.1 - 9.3e-15 54.7 0.5 5.1e-06 26.5 0.2 2.6 2 1 0 2 2 2 2 RanBP1 domain DEAD PF00270.24 KEY70866.1 - 3.1e-24 85.3 0.0 5.6e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 KEY70866.1 - 3.6e-14 53.0 0.5 1.1e-13 51.5 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 KEY70866.1 - 3.9e-09 36.2 0.0 1.8e-08 34.1 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEY70866.1 - 5.2e-05 23.1 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.6 KEY70866.1 - 0.00028 20.8 0.3 0.00065 19.6 0.2 1.7 1 1 0 1 1 1 1 DNA replication factor CDT1 like Terminase_GpA PF05876.7 KEY70866.1 - 0.022 13.1 0.0 0.034 12.5 0.0 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Na_Ca_ex PF01699.19 KEY70867.1 - 3.4e-21 75.3 30.7 1.9e-13 50.2 8.8 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF4131 PF13567.1 KEY70867.1 - 0.08 12.3 7.3 4 6.8 0.2 3.4 2 1 2 4 4 4 0 Domain of unknown function (DUF4131) Vma12 PF11712.3 KEY70867.1 - 0.35 10.5 5.4 1 9.0 0.1 2.7 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF872 PF05915.7 KEY70867.1 - 2.2 8.1 6.2 0.96 9.3 0.4 3.0 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) MIF4G PF02854.14 KEY70868.1 - 3e-57 193.4 0.0 2.4e-25 89.2 0.0 3.9 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.9 KEY70868.1 - 6.1e-53 179.0 16.7 2e-52 177.4 11.6 1.9 1 0 0 1 1 1 1 Up-frameshift suppressor 2 SDP_N PF12278.3 KEY70868.1 - 0.0076 15.8 7.8 0.32 10.6 0.7 2.8 2 0 0 2 2 2 2 Sex determination protein N terminal CBP4 PF07960.6 KEY70868.1 - 0.034 13.7 0.0 0.034 13.7 0.0 2.9 3 0 0 3 3 3 0 CBP4 Chitin_synth_2 PF03142.10 KEY70869.1 - 8.9e-25 87.0 2.6 1.2e-22 80.0 0.9 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 KEY70869.1 - 1.1e-18 67.9 0.1 2.4e-18 66.7 0.1 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KEY70869.1 - 2.1e-18 66.7 6.3 2.1e-18 66.7 4.4 2.5 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KEY70869.1 - 0.1 12.2 0.1 5.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 HSP70 PF00012.15 KEY70870.1 - 8e-163 542.5 2.3 8e-163 542.5 1.6 1.6 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KEY70870.1 - 2.9e-13 49.1 0.0 2.9e-13 49.1 0.0 2.4 3 0 0 3 3 3 1 MreB/Mbl protein FtsA PF14450.1 KEY70870.1 - 2.6e-05 24.0 0.4 0.27 11.0 0.1 3.4 2 1 0 2 2 2 2 Cell division protein FtsA Trans_reg_C PF00486.23 KEY70870.1 - 0.082 12.8 0.0 0.31 10.9 0.0 2.0 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal GTP_EFTU PF00009.22 KEY70871.1 - 1.4e-31 109.4 0.0 7.4e-31 107.0 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KEY70871.1 - 1.4e-17 63.5 0.0 3.4e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KEY70871.1 - 4.2e-11 42.8 4.0 3.1e-08 33.6 0.1 3.2 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEY70871.1 - 2.8e-07 30.5 0.1 1.3e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KEY70871.1 - 0.00027 21.4 0.0 0.0012 19.2 0.0 2.2 1 0 0 1 1 1 1 Miro-like protein ATP_bind_1 PF03029.12 KEY70871.1 - 0.011 15.2 0.0 0.043 13.3 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 KEY70871.1 - 0.19 11.7 0.0 0.19 11.7 0.0 3.5 3 0 0 3 3 3 0 AAA ATPase domain MMS1_N PF10433.4 KEY70872.1 - 5e-88 295.4 0.0 1e-87 294.4 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Inh PF02974.9 KEY70872.1 - 0.1 12.1 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 Protease inhibitor Inh RabGAP-TBC PF00566.13 KEY70873.1 - 2.1e-22 79.6 0.0 3.1e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF883 PF05957.8 KEY70873.1 - 0.058 13.8 0.5 0.15 12.4 0.3 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Vps52 PF04129.7 KEY70874.1 - 4e-114 381.9 8.0 1e-113 380.5 5.6 1.6 1 1 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 KEY70874.1 - 0.0013 16.9 7.7 0.014 13.5 5.3 2.0 1 1 0 1 1 1 1 Exocyst complex component Sec3 DUF1664 PF07889.7 KEY70874.1 - 0.0079 15.9 0.1 0.019 14.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Mer2 PF09074.5 KEY70874.1 - 0.036 13.9 0.7 0.078 12.9 0.1 1.9 2 0 0 2 2 2 0 Mer2 Pkip-1 PF06878.6 KEY70874.1 - 0.15 11.9 3.0 0.27 11.1 0.2 2.2 2 0 0 2 2 2 0 Pkip-1 protein eIF-5a PF01287.15 KEY70875.1 - 8.9e-26 89.6 1.4 1.3e-25 89.1 1.0 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 KEY70875.1 - 0.0042 16.7 0.7 0.0042 16.7 0.5 1.9 2 0 0 2 2 2 1 KOW motif Response_reg PF00072.19 KEY70875.1 - 0.048 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Response regulator receiver domain EFP_N PF08207.7 KEY70875.1 - 0.097 12.5 0.2 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain RRN7 PF11781.3 KEY70876.1 - 0.0008 18.8 1.8 0.0015 17.9 1.3 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 Pkip-1 PF06878.6 KEY70876.1 - 0.088 12.6 0.0 0.22 11.3 0.0 1.6 2 0 0 2 2 2 0 Pkip-1 protein Yip1 PF04893.12 KEY70877.1 - 5.7e-14 51.9 15.7 7.1e-14 51.6 10.7 1.4 1 1 0 1 1 1 1 Yip1 domain Rhodanese PF00581.15 KEY70878.1 - 2.6e-11 43.8 0.0 4.1e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain p450 PF00067.17 KEY70879.1 - 4.2e-50 170.6 0.0 7.2e-50 169.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF2636 PF11120.3 KEY70879.1 - 0.084 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) BCDHK_Adom3 PF10436.4 KEY70880.1 - 4e-39 133.7 0.0 6.1e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KEY70880.1 - 4.9e-16 58.4 0.0 5.4e-15 55.0 0.0 2.5 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Inhibitor_I9 PF05922.11 KEY70880.1 - 3.2e-10 40.4 0.1 7.6e-10 39.2 0.1 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 HATPase_c_2 PF13581.1 KEY70880.1 - 0.02 14.6 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Chitin_synth_2 PF03142.10 KEY70881.1 - 3.3e-229 761.6 0.0 4.4e-229 761.2 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KEY70881.1 - 1.3e-56 192.0 0.0 3.7e-45 154.1 0.0 2.5 2 1 0 2 2 2 2 Myosin head (motor domain) Glyco_trans_2_3 PF13632.1 KEY70881.1 - 3.1e-17 62.9 2.4 3.1e-17 62.9 1.7 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KEY70881.1 - 1.8e-14 54.1 0.0 1.1e-11 44.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 DEK_C PF08766.6 KEY70881.1 - 4.7e-14 51.9 4.5 3.3e-13 49.1 2.8 2.3 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 KEY70881.1 - 6.2e-13 48.3 0.0 3.3e-09 36.4 0.0 2.8 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 KEY70881.1 - 1.1e-05 24.8 0.0 2.6e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KEY70881.1 - 0.00044 19.9 0.0 0.028 14.1 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.1 KEY70881.1 - 0.022 15.0 0.1 0.085 13.1 0.1 2.0 1 0 0 1 1 1 0 Glycosyl transferase family 2 Chitin_synth_2 PF03142.10 KEY70882.1 - 6.2e-253 839.9 1.5 8.1e-253 839.5 1.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KEY70882.1 - 2e-170 568.1 0.0 2.6e-170 567.8 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 KEY70882.1 - 2e-16 59.4 0.2 1.5e-15 56.6 0.2 2.3 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 KEY70882.1 - 3.1e-15 55.7 0.1 1.8e-09 37.2 0.0 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 KEY70882.1 - 3.6e-14 52.9 5.6 3.6e-14 52.9 3.9 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KEY70882.1 - 4e-13 49.6 0.5 2.9e-09 37.0 0.1 2.9 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KEY70882.1 - 6.3e-06 25.9 0.0 0.0012 18.5 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_16 PF13191.1 KEY70882.1 - 0.00052 20.0 0.4 0.0034 17.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 KEY70882.1 - 0.001 18.9 0.4 1.3 9.0 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_29 PF13555.1 KEY70882.1 - 0.007 15.8 0.1 0.023 14.2 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KEY70882.1 - 0.0073 16.4 0.4 0.033 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KEY70882.1 - 0.0082 15.5 0.2 0.068 12.5 0.1 2.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KEY70882.1 - 0.017 15.3 0.1 0.056 13.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Glyco_transf_21 PF13506.1 KEY70882.1 - 0.027 13.7 0.0 0.12 11.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 21 DUF258 PF03193.11 KEY70882.1 - 0.053 12.7 0.1 0.2 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KEY70882.1 - 0.08 13.1 0.0 0.29 11.3 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 KEY70882.1 - 0.1 12.3 0.1 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2592 PF10766.4 KEY70882.1 - 0.11 11.9 1.0 0.29 10.4 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2592) Npa1 PF11707.3 KEY70883.1 - 5.3e-79 265.6 0.0 1.2e-78 264.4 0.0 1.6 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal CP12 PF02672.10 KEY70883.1 - 3.4 8.2 5.9 5.9 7.4 0.0 3.3 3 0 0 3 3 3 0 CP12 domain His_Phos_2 PF00328.17 KEY70885.1 - 2.5e-47 161.8 0.0 2.9e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) p450 PF00067.17 KEY70887.1 - 8.2e-43 146.5 0.1 1.2e-29 103.1 0.1 2.7 2 1 0 2 2 2 2 Cytochrome P450 Fungal_trans PF04082.13 KEY70888.1 - 3.3e-09 35.9 0.1 5.6e-09 35.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PS-DH PF14765.1 KEY70889.1 - 7e-63 212.5 0.1 1.3e-62 211.6 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.21 KEY70889.1 - 1e-59 202.0 0.1 2.9e-59 200.6 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEY70889.1 - 1.7e-54 185.3 1.9 2.6e-54 184.7 0.1 2.1 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.5 KEY70889.1 - 5.9e-52 175.9 1.2 4.6e-51 173.0 0.1 2.6 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KEY70889.1 - 2.2e-39 135.0 5.3 7.3e-39 133.3 0.2 3.2 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KEY70889.1 - 6e-31 106.7 0.0 1.4e-30 105.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KEY70889.1 - 3.2e-15 55.8 0.4 1.3e-13 50.5 0.2 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 KEY70889.1 - 3.8e-08 33.4 0.1 1.1e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 KEY70889.1 - 4.8e-08 33.3 0.1 3.2e-07 30.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY70889.1 - 4.2e-06 26.4 0.0 1.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 KEY70889.1 - 4.3e-05 23.2 0.0 0.00013 21.6 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 KEY70889.1 - 0.00014 22.3 0.3 0.00068 20.0 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY70889.1 - 0.00032 20.4 0.0 0.00099 18.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 KEY70889.1 - 0.00055 18.7 0.0 0.00099 17.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.13 KEY70889.1 - 0.0015 17.7 0.0 0.0032 16.6 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Polysacc_synt_2 PF02719.10 KEY70889.1 - 0.0035 16.2 0.0 0.008 15.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Thiolase_N PF00108.18 KEY70889.1 - 0.0083 15.1 0.1 0.018 14.0 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KEY70889.1 - 0.012 15.2 0.7 0.048 13.3 0.1 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NodS PF05401.6 KEY70889.1 - 0.092 12.1 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF2758 PF10957.3 KEY70889.1 - 0.29 10.9 0.0 0.68 9.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2758) MFS_1 PF07690.11 KEY70890.1 - 1.6e-31 109.3 57.4 1.3e-30 106.2 39.1 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY70890.1 - 1.8e-08 33.4 14.2 1.8e-08 33.4 9.8 3.8 2 1 1 3 3 3 1 Sugar (and other) transporter Inositol_P PF00459.20 KEY70892.1 - 5.5e-59 199.6 0.2 4.3e-58 196.7 0.1 1.9 1 1 0 1 1 1 1 Inositol monophosphatase family La PF05383.12 KEY70893.1 - 6.6e-14 51.4 0.0 1e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 KEY70893.1 - 5e-10 38.8 0.3 8.7e-10 38.0 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY70893.1 - 4.2e-09 36.2 0.0 7.7e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY70893.1 - 0.00011 21.9 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FBP PF07299.6 KEY70893.1 - 0.079 12.2 0.1 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein (FBP) API5 PF05918.6 KEY70893.1 - 2.8 6.3 8.2 4.2 5.7 5.7 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) PLA2_B PF01735.13 KEY70894.1 - 1.5e-27 95.9 0.0 7.4e-27 93.6 0.0 1.8 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.17 KEY70894.1 - 0.12 12.3 1.6 8.2 6.2 0.2 2.4 2 0 0 2 2 2 0 Patatin-like phospholipase Endonuc_Holl PF10107.4 KEY70894.1 - 4.4 6.9 7.6 0.47 10.1 1.2 2.2 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Ribonucleas_3_3 PF14622.1 KEY70895.1 - 2.4e-07 30.7 0.0 0.0011 18.9 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KEY70895.1 - 2e-06 28.2 0.0 1.4e-05 25.5 0.0 2.3 2 1 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.20 KEY70895.1 - 0.0012 19.3 0.0 0.0024 18.3 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif zf-RING_2 PF13639.1 KEY70897.1 - 2.5e-14 52.8 7.4 2.5e-14 52.8 5.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KEY70897.1 - 2.6e-09 36.6 10.1 4.7e-08 32.5 2.5 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEY70897.1 - 5.5e-07 29.5 3.2 5.5e-07 29.5 2.2 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KEY70897.1 - 6.3e-07 28.9 14.8 1.1e-06 28.2 4.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEY70897.1 - 1.4e-05 25.0 6.3 1.4e-05 25.0 4.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY70897.1 - 0.00027 20.6 4.6 0.00027 20.6 3.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 KEY70897.1 - 0.00069 19.1 2.9 0.0017 17.8 2.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 KEY70897.1 - 0.0023 17.7 1.6 0.0023 17.7 1.1 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.14 KEY70897.1 - 0.0046 16.6 0.3 0.0046 16.6 0.2 2.1 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family DNA_ligase_ZBD PF03119.11 KEY70897.1 - 0.39 10.4 5.4 6 6.6 0.5 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-RING_3 PF14369.1 KEY70897.1 - 0.47 10.4 10.0 0.052 13.5 2.5 2.5 2 0 0 2 2 2 0 zinc-finger RRN7 PF11781.3 KEY70897.1 - 1 8.9 4.4 8.8 5.9 1.4 2.6 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 KEY70897.1 - 1 9.2 5.3 2.9 7.7 0.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.1 KEY70897.1 - 1.2 8.7 11.0 0.51 9.9 2.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.7 KEY70897.1 - 2.5 7.9 7.2 6.1 6.7 0.2 2.8 2 1 1 3 3 3 0 zinc-ribbons zf-RING-like PF08746.6 KEY70897.1 - 5.5 7.0 14.0 0.12 12.3 3.5 2.3 2 1 0 2 2 2 0 RING-like domain Baculo_RING PF05883.6 KEY70897.1 - 6.2 6.6 5.2 1 9.2 0.9 1.6 2 0 0 2 2 1 0 Baculovirus U-box/Ring-like domain tRNA-synt_2 PF00152.15 KEY70898.1 - 7.6e-75 251.7 0.2 1.8e-74 250.5 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 KEY70898.1 - 1.5e-18 66.6 0.1 2.4e-18 65.9 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 KEY70898.1 - 0.0002 21.1 0.0 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Abhydrolase_3 PF07859.8 KEY70899.1 - 1.3e-41 142.5 0.0 1.7e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KEY70899.1 - 2.3e-08 33.2 0.1 1.6e-07 30.4 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KEY70899.1 - 3.5e-05 23.1 0.0 0.066 12.4 0.0 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEY70899.1 - 4.6e-05 23.2 0.0 5.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY70899.1 - 0.0036 17.2 0.2 0.006 16.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KEY70899.1 - 0.029 13.8 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase GLTP PF08718.6 KEY70900.1 - 1.3e-45 155.0 0.0 1.8e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PLDc PF00614.17 KEY70901.1 - 1.4e-12 46.9 1.3 1.1e-06 28.2 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KEY70901.1 - 3.4e-11 42.9 0.0 0.00012 21.8 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain BRO1 PF03097.13 KEY70903.1 - 2.5e-133 444.4 3.8 5.9e-133 443.2 2.6 1.6 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KEY70903.1 - 1.3e-95 319.8 22.3 1.7e-95 319.4 14.9 1.6 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV NYD-SP28 PF14772.1 KEY70903.1 - 0.0091 16.0 1.3 0.0091 16.0 0.9 3.1 2 1 1 3 3 3 1 Sperm tail AAA PF00004.24 KEY70904.1 - 7.2e-12 45.6 0.0 1.4e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEY70904.1 - 2.6e-07 30.8 0.0 6.9e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEY70904.1 - 6.8e-06 25.8 0.0 1.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KEY70904.1 - 8.5e-05 21.7 0.0 0.00015 20.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KEY70904.1 - 9.3e-05 22.1 0.1 0.00039 20.1 0.0 2.1 2 0 0 2 2 1 1 Part of AAA domain AAA_33 PF13671.1 KEY70904.1 - 0.00011 22.1 0.0 0.00031 20.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEY70904.1 - 0.00043 21.1 0.0 0.0021 18.8 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KEY70904.1 - 0.00045 20.1 0.0 0.0008 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KEY70904.1 - 0.00054 18.7 0.0 0.001 17.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 KEY70904.1 - 0.0024 17.8 0.8 0.0083 16.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 KEY70904.1 - 0.0092 15.9 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) NTPase_1 PF03266.10 KEY70904.1 - 0.019 14.7 0.4 0.12 12.0 0.1 2.2 1 1 1 2 2 2 0 NTPase Zeta_toxin PF06414.7 KEY70904.1 - 0.022 13.8 0.0 0.069 12.2 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 KEY70904.1 - 0.035 14.4 0.0 0.071 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TOMM6 PF15184.1 KEY70904.1 - 0.056 12.7 0.1 0.15 11.4 0.1 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog IstB_IS21 PF01695.12 KEY70904.1 - 0.072 12.4 0.1 0.18 11.1 0.1 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF258 PF03193.11 KEY70904.1 - 0.073 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 KEY70904.1 - 0.099 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.1 KEY70904.1 - 0.13 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain S4 PF01479.20 KEY70905.1 - 1.5e-14 53.1 0.0 2.7e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 KEY70905.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 S4 domain Fungal_trans PF04082.13 KEY70906.1 - 5.9e-42 143.3 0.0 9.2e-42 142.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY70906.1 - 3e-08 33.4 6.8 7e-08 32.2 4.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1844 PF08899.6 KEY70906.1 - 0.17 11.8 0.0 0.46 10.4 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1844) Fungal_trans PF04082.13 KEY70907.1 - 6e-26 90.8 0.0 1.7e-25 89.4 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY70907.1 - 2e-09 37.2 7.6 3.5e-09 36.4 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEY70907.1 - 0.024 13.2 0.0 0.045 12.3 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain TFIIF_alpha PF05793.7 KEY70908.1 - 0.097 11.0 7.3 0.16 10.2 5.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Hex_IIIa PF02455.11 KEY70908.1 - 0.57 8.7 6.6 0.17 10.5 2.7 1.4 2 0 0 2 2 2 0 Hexon-associated protein (IIIa) PBP1_TM PF14812.1 KEY70908.1 - 8.6 6.7 14.4 0.51 10.6 5.6 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Amidohydro_1 PF01979.15 KEY70909.1 - 1e-47 163.4 0.0 1.2e-47 163.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KEY70909.1 - 2.1e-08 34.5 1.6 8.2e-07 29.3 1.1 2.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KEY70909.1 - 1.7e-07 30.7 6.8 1.6e-06 27.6 0.2 2.9 2 2 1 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 KEY70909.1 - 1.1e-06 28.3 0.0 2.7e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Acyl_transf_1 PF00698.16 KEY70910.1 - 5e-80 269.1 0.0 6.2e-78 262.3 0.0 3.1 3 1 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 KEY70910.1 - 1.7e-38 130.7 0.1 4.2e-38 129.4 0.0 1.8 2 0 0 2 2 2 1 MaoC like domain DUF1729 PF08354.5 KEY70910.1 - 5e-29 99.8 0.9 1.5e-28 98.3 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 KEY70910.1 - 1.4e-22 79.9 0.0 4.3e-22 78.3 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 KEY70910.1 - 0.0029 16.8 0.3 0.094 11.8 0.2 2.5 1 1 0 1 1 1 1 Nitronate monooxygenase ketoacyl-synt PF00109.21 KEY70911.1 - 3.9e-21 75.6 0.0 8.2e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 KEY70911.1 - 1.4e-17 63.5 0.0 3.3e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 KEY70911.1 - 3.7e-11 42.9 0.0 1.4e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KEY70911.1 - 4.2e-06 26.7 0.0 1.7e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY70911.1 - 0.00011 21.8 0.1 0.0008 19.1 0.0 2.4 2 0 0 2 2 2 1 KR domain BIV_Env PF05858.7 KEY70911.1 - 0.21 9.4 0.4 8.9 4.1 0.1 2.4 2 0 0 2 2 2 0 Bovine immunodeficiency virus surface protein (SU) LSM PF01423.17 KEY70912.1 - 6.4e-15 54.4 0.0 9.4e-15 53.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain PPR_3 PF13812.1 KEY70913.1 - 1.5e-12 46.7 5.0 0.00012 22.0 0.0 6.8 7 1 1 8 8 8 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 KEY70913.1 - 4.1e-08 33.0 0.0 0.063 13.2 0.0 5.1 5 0 0 5 5 5 2 PPR repeat family PPR PF01535.15 KEY70913.1 - 4.3e-06 26.3 0.1 0.69 10.0 0.0 5.8 7 0 0 7 7 7 1 PPR repeat DCAF15_WD40 PF14939.1 KEY70913.1 - 0.088 12.1 0.1 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat PPR_1 PF12854.2 KEY70913.1 - 0.31 10.5 2.7 0.33 10.4 0.0 2.5 3 0 0 3 3 3 0 PPR repeat Zn_clus PF00172.13 KEY70914.1 - 2e-06 27.6 11.0 4e-06 26.6 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop14 PF04147.7 KEY70914.1 - 0.013 13.4 8.1 0.02 12.8 5.6 1.3 1 0 0 1 1 1 0 Nop14-like family Ku PF02735.11 KEY70915.1 - 1.4e-39 135.5 0.0 5.2e-39 133.7 0.0 1.9 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KEY70915.1 - 4.5e-36 124.3 0.0 6.4e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 KEY70915.1 - 3.9e-15 56.1 1.8 1.1e-14 54.7 1.3 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 KEY70915.1 - 8.3e-12 44.3 0.1 1.6e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 SAP domain Toprim_3 PF13362.1 KEY70915.1 - 0.0062 16.7 0.0 0.14 12.3 0.0 2.7 2 0 0 2 2 2 1 Toprim domain HeH PF12949.2 KEY70915.1 - 0.015 14.8 0.1 0.039 13.4 0.1 1.8 1 0 0 1 1 1 0 HeH/LEM domain Ferrochelatase PF00762.14 KEY70916.1 - 1.6e-91 306.5 0.0 1.9e-91 306.3 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase MP PF01107.13 KEY70916.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Viral movement protein (MP) Septin PF00735.13 KEY70917.1 - 4.8e-121 403.0 0.2 4.8e-121 403.0 0.2 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KEY70917.1 - 5e-07 29.6 0.0 1.1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 KEY70917.1 - 8e-05 22.9 0.6 0.025 14.9 0.0 2.6 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 KEY70917.1 - 0.00011 21.4 0.4 0.00078 18.6 0.3 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KEY70917.1 - 0.00011 21.6 0.7 0.00092 18.6 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 KEY70917.1 - 0.00089 18.4 1.3 0.0024 17.0 0.0 2.1 2 0 0 2 2 2 1 AIG1 family AAA_10 PF12846.2 KEY70917.1 - 0.001 18.5 2.3 0.0032 16.9 0.2 2.3 2 2 1 3 3 3 1 AAA-like domain AAA_16 PF13191.1 KEY70917.1 - 0.0031 17.5 0.0 0.017 15.1 0.0 2.2 3 0 0 3 3 2 1 AAA ATPase domain Miro PF08477.8 KEY70917.1 - 0.0045 17.4 0.4 0.015 15.8 0.0 2.1 2 0 0 2 2 1 1 Miro-like protein Ras PF00071.17 KEY70917.1 - 0.0075 15.6 0.3 0.046 13.1 0.0 2.3 2 0 0 2 2 2 1 Ras family FtsK_SpoIIIE PF01580.13 KEY70917.1 - 0.008 15.6 0.0 0.028 13.8 0.0 1.9 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.1 KEY70917.1 - 0.0086 16.2 0.0 0.044 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEY70917.1 - 0.0091 15.5 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 KEY70917.1 - 0.0095 15.7 4.1 0.7 9.6 0.0 3.3 3 0 0 3 3 3 1 Dynamin family RNA_helicase PF00910.17 KEY70917.1 - 0.055 13.6 1.0 0.66 10.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 KEY70917.1 - 0.058 13.1 2.4 0.3 10.8 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 KEY70917.1 - 0.11 12.0 0.6 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_32 PF13654.1 KEY70917.1 - 0.18 10.4 10.3 0.58 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain IncA PF04156.9 KEY70917.1 - 1.2 8.7 6.8 1.9 8.0 4.7 1.3 1 0 0 1 1 1 0 IncA protein Fis1_TPR_C PF14853.1 KEY70918.1 - 7.7e-26 89.7 2.1 1.4e-25 88.9 1.5 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 KEY70918.1 - 1.1e-17 62.9 0.0 2.3e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_16 PF13432.1 KEY70918.1 - 0.0029 18.2 0.3 0.0062 17.1 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEY70918.1 - 0.004 16.9 1.5 0.0096 15.7 1.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Spc24 PF08286.6 KEY70919.1 - 1.8e-39 134.1 0.3 2.3e-38 130.5 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Reo_sigmaC PF04582.7 KEY70919.1 - 0.021 14.0 1.2 0.027 13.6 0.8 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Retrotrans_gag PF03732.12 KEY70919.1 - 0.055 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein EAP30 PF04157.11 KEY70919.1 - 0.29 10.2 6.3 1.2 8.2 1.3 2.1 1 1 1 2 2 2 0 EAP30/Vps36 family PKI PF02827.11 KEY70919.1 - 0.31 11.1 3.2 2.3 8.3 0.2 2.6 1 1 2 3 3 3 0 cAMP-dependent protein kinase inhibitor LEAP-2 PF07359.6 KEY70920.1 - 0.00078 19.0 2.6 0.0019 17.8 1.8 1.6 1 0 0 1 1 1 1 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) PspC PF04024.7 KEY70920.1 - 0.061 12.7 0.4 0.11 11.9 0.3 1.4 1 0 0 1 1 1 0 PspC domain TatD_DNase PF01026.16 KEY70921.1 - 6.1e-28 97.7 0.0 1e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase Fungal_trans PF04082.13 KEY70922.1 - 1.8e-24 86.0 0.3 2.8e-24 85.3 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY70922.1 - 9.9e-08 31.7 10.5 1.9e-07 30.8 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyridox_oxase_2 PF12766.2 KEY70923.1 - 7.1e-21 74.4 0.0 1.3e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CHASE3 PF05227.8 KEY70924.1 - 0.027 14.1 0.4 0.027 14.1 0.3 2.8 3 1 0 3 3 3 0 CHASE3 domain Pkinase PF00069.20 KEY70925.1 - 2e-25 89.4 0.0 3e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 KEY70925.1 - 1.5e-14 53.2 5.5 4.1e-07 29.6 0.0 5.2 4 0 0 4 4 4 3 WD domain, G-beta repeat HEAT PF02985.17 KEY70925.1 - 4.3e-10 38.8 3.4 0.025 14.6 0.1 6.8 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 KEY70925.1 - 7.3e-06 26.1 1.3 0.08 13.2 0.0 4.3 1 1 2 3 3 3 2 HEAT repeats Pkinase_Tyr PF07714.12 KEY70925.1 - 5.8e-05 22.2 0.0 9.1e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 KEY70925.1 - 0.0014 19.0 1.1 1.9 9.0 0.1 4.3 5 0 0 5 5 5 1 HEAT-like repeat APH PF01636.18 KEY70925.1 - 0.008 15.9 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEY70925.1 - 0.03 13.3 0.0 0.085 11.8 0.0 1.7 1 0 0 1 1 1 0 Kinase-like Adaptin_N PF01602.15 KEY70925.1 - 0.21 9.8 0.4 3.3 5.9 0.0 2.1 2 0 0 2 2 2 0 Adaptin N terminal region LRR_9 PF14580.1 KEY70926.1 - 2.3e-49 167.3 0.0 3.7e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 KEY70926.1 - 4e-10 39.2 6.6 3.3e-06 26.7 0.9 3.5 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 KEY70926.1 - 6.2e-09 35.2 1.9 6.3e-05 22.4 1.1 3.8 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KEY70926.1 - 0.0006 19.5 2.1 1.1 9.7 0.2 4.7 5 0 0 5 5 5 1 Leucine rich repeat LRR_1 PF00560.28 KEY70926.1 - 0.0026 17.5 1.1 45 4.6 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.1 KEY70926.1 - 0.025 14.6 0.5 16 5.9 0.1 4.3 6 0 0 6 6 6 0 Leucine Rich repeat CHAT PF12770.2 KEY70926.1 - 0.033 13.3 0.2 0.041 13.0 0.2 1.1 1 0 0 1 1 1 0 CHAT domain DUF4349 PF14257.1 KEY70926.1 - 0.19 10.9 3.4 0.34 10.1 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) CBFD_NFYB_HMF PF00808.18 KEY70927.1 - 2.1e-11 43.7 0.2 3.2e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KEY70927.1 - 0.012 15.7 0.1 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Voltage_CLC PF00654.15 KEY70928.1 - 1.4e-89 300.5 25.9 1.4e-89 300.5 17.9 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KEY70928.1 - 9.5e-10 38.1 0.1 4.9e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 CBS domain EmrE PF13536.1 KEY70929.1 - 0.00084 19.5 6.5 0.00084 19.5 4.5 1.6 1 1 1 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 KEY70929.1 - 0.0079 16.2 13.4 0.018 15.0 9.3 1.6 1 1 0 1 1 1 1 EamA-like transporter family UPF0546 PF10639.4 KEY70929.1 - 0.082 12.7 3.8 0.12 12.2 2.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 DUF2754 PF10953.3 KEY70929.1 - 1.4 9.0 5.0 1.7 8.7 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2754) TFIIA_gamma_C PF02751.9 KEY70930.1 - 6.6e-26 89.8 1.6 9e-26 89.4 1.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 KEY70930.1 - 2e-24 84.8 0.4 2.9e-24 84.4 0.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain ATP-synt_C PF00137.16 KEY70931.1 - 4.9e-23 80.8 31.6 7.8e-16 57.7 7.0 2.6 3 0 0 3 3 3 2 ATP synthase subunit C MoCF_biosynth PF00994.19 KEY70932.1 - 6.1e-54 181.3 0.3 9.5e-30 102.8 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 KEY70932.1 - 1.9e-34 118.3 3.9 5.3e-34 116.9 2.9 1.6 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 KEY70932.1 - 6.4e-15 54.8 0.7 1.8e-14 53.3 0.0 2.2 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) SelP_N PF04592.9 KEY70932.1 - 5.3 6.3 12.0 8.2 5.7 8.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RNase_P_Rpp14 PF01900.14 KEY70933.1 - 6.5e-36 122.4 0.0 8.5e-36 122.1 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family ATP_bind_1 PF03029.12 KEY70934.1 - 5.8e-79 264.9 0.0 9.4e-79 264.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 KEY70934.1 - 0.00065 19.1 0.0 0.004 16.5 0.0 2.0 1 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 KEY70934.1 - 0.0035 16.1 0.0 0.0074 15.0 0.0 1.4 1 0 0 1 1 1 1 ArgK protein AAA_29 PF13555.1 KEY70934.1 - 0.016 14.7 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KEY70934.1 - 0.016 14.3 0.6 0.31 10.1 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_10 PF12846.2 KEY70934.1 - 0.035 13.5 0.0 0.083 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 KEY70934.1 - 0.039 13.8 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 KEY70934.1 - 0.12 11.7 0.0 1.9 7.9 0.0 2.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 KEY70934.1 - 0.15 12.8 5.5 0.16 12.8 0.5 2.9 1 1 1 3 3 3 0 AAA domain Vir_act_alpha_C PF10400.4 KEY70934.1 - 0.39 11.1 0.1 0.39 11.1 0.0 2.3 2 0 0 2 2 2 0 Virulence activator alpha C-term cNMP_binding PF00027.24 KEY70935.1 - 5.3e-39 131.9 0.0 1.2e-17 63.4 0.0 4.7 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 KEY70935.1 - 4.7e-16 59.3 5.9 1.1e-14 54.9 4.1 2.7 1 1 0 1 1 1 1 Patatin-like phospholipase Zip PF02535.17 KEY70936.1 - 0.0099 14.9 0.1 0.012 14.6 0.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter U79_P34 PF03064.11 KEY70936.1 - 0.053 13.0 17.7 0.069 12.6 12.3 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF3827 PF12877.2 KEY70936.1 - 9.5 4.1 7.2 12 3.8 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Pyridoxal_deC PF00282.14 KEY70937.1 - 1.3e-107 359.4 0.0 1.6e-107 359.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF1382 PF07131.6 KEY70937.1 - 0.032 14.3 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) EMP70 PF02990.11 KEY70938.1 - 3.6e-158 527.2 0.1 1.4e-157 525.3 0.0 1.9 1 1 0 1 1 1 1 Endomembrane protein 70 Bul1_N PF04425.7 KEY70939.1 - 1.2e-05 24.0 0.1 6.1e-05 21.7 0.0 1.9 2 0 0 2 2 2 1 Bul1 N terminus Bul1_C PF04426.7 KEY70939.1 - 9e-05 21.7 0.0 0.0004 19.6 0.0 1.8 2 0 0 2 2 2 1 Bul1 C terminus Arrestin_C PF02752.17 KEY70939.1 - 0.041 13.9 0.0 0.38 10.8 0.0 2.5 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Zip PF02535.17 KEY70941.1 - 2.7e-44 151.4 2.7 3.9e-44 150.9 1.9 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Glyco_hydro_17 PF00332.13 KEY70942.1 - 2.3e-05 23.6 0.1 3.9e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.8 KEY70942.1 - 0.12 11.0 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 PQQ PF01011.16 KEY70942.1 - 0.18 11.3 1.7 0.33 10.5 0.3 2.2 2 0 0 2 2 2 0 PQQ enzyme repeat Nucleoporin_FG PF13634.1 KEY70942.1 - 1.6 8.9 7.4 0.76 10.0 2.5 2.4 2 1 0 2 2 2 0 Nucleoporin FG repeat region Hamartin PF04388.7 KEY70943.1 - 1.7e-39 136.0 18.5 2.8e-39 135.3 12.9 1.2 1 0 0 1 1 1 1 Hamartin protein DUF4066 PF13278.1 KEY70944.1 - 2.6e-24 85.3 0.3 1.9e-21 76.0 0.0 2.1 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 KEY70944.1 - 3.1e-05 23.4 0.0 6.6e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family SNO PF01174.14 KEY70944.1 - 0.087 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Peptidase_S51 PF03575.12 KEY70944.1 - 0.15 11.7 0.0 0.43 10.2 0.0 1.8 2 0 0 2 2 2 0 Peptidase family S51 SAP PF02037.22 KEY70945.1 - 7.2e-12 44.5 0.3 1.3e-11 43.7 0.2 1.4 1 0 0 1 1 1 1 SAP domain RRM_6 PF14259.1 KEY70945.1 - 0.011 15.7 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY70945.1 - 0.053 13.3 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CPSase_sm_chain PF00988.17 KEY70946.1 - 4.3e-46 155.6 0.0 7.3e-46 154.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KEY70946.1 - 6.6e-42 143.1 0.0 9.1e-42 142.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KEY70946.1 - 5.1e-05 22.8 0.3 0.00026 20.4 0.2 2.2 1 1 0 1 1 1 1 Peptidase C26 ETF PF01012.16 KEY70947.1 - 1.3e-34 119.2 0.5 1.7e-34 118.9 0.3 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ArfGap PF01412.13 KEY70948.1 - 1.7e-33 114.8 0.5 3.2e-33 113.9 0.1 1.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf RRM_1 PF00076.17 KEY70949.1 - 5.1e-31 106.1 0.2 6.5e-15 54.5 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY70949.1 - 5.7e-25 87.0 0.0 2.6e-12 46.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY70949.1 - 1.4e-08 34.4 0.0 0.0041 16.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 KEY70949.1 - 0.038 13.6 0.1 6.2 6.5 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain ATP-synt_B PF00430.13 KEY70949.1 - 0.21 11.3 3.2 0.58 9.9 2.2 1.7 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) API5 PF05918.6 KEY70949.1 - 0.37 9.2 4.1 0.53 8.7 2.8 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) FAD_binding_1 PF00667.15 KEY70950.1 - 1.9e-32 112.5 0.0 3.5e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KEY70950.1 - 7.7e-28 97.2 0.0 1.1e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KEY70950.1 - 1.8e-15 57.4 0.0 3.8e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Asp PF00026.18 KEY70951.1 - 4e-12 46.0 0.0 1.6e-11 44.0 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Pox_G5 PF04599.7 KEY70951.1 - 0.075 11.7 0.1 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein Gcd10p PF04189.8 KEY70952.1 - 0.1 11.7 0.0 3.2 6.7 0.0 2.1 2 0 0 2 2 2 0 Gcd10p family F-box-like PF12937.2 KEY70953.1 - 1.8e-09 37.1 0.1 3.4e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEY70953.1 - 1.3e-08 34.3 0.5 2.9e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 F-box domain UIM PF02809.15 KEY70953.1 - 2.5 7.9 17.9 0.015 14.8 2.6 2.9 3 0 0 3 3 3 0 Ubiquitin interaction motif FYVE_2 PF02318.11 KEY70954.1 - 0.043 13.7 18.6 0.16 11.8 1.7 3.5 3 0 0 3 3 3 0 FYVE-type zinc finger Siva PF05458.7 KEY70954.1 - 0.047 13.2 8.3 0.22 11.0 0.7 2.5 2 0 0 2 2 2 0 Cd27 binding protein (Siva) HypA PF01155.14 KEY70954.1 - 0.23 11.1 23.4 1.1 8.9 1.3 3.3 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family UPF0547 PF10571.4 KEY70954.1 - 7.4 6.3 21.4 0.38 10.5 2.2 3.5 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 Clr2 PF10383.4 KEY70955.1 - 3.1e-09 36.9 0.0 2.5e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 SMC_Nse1 PF07574.8 KEY70956.1 - 2e-39 135.2 0.0 2.5e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 KEY70956.1 - 1.8e-12 47.0 9.0 2.7e-12 46.4 6.2 1.3 1 0 0 1 1 1 1 RING-like domain C1_1 PF00130.17 KEY70956.1 - 0.0033 17.1 2.8 0.0033 17.1 2.0 1.5 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Rpr2 PF04032.11 KEY70956.1 - 0.46 10.3 3.4 0.89 9.4 2.4 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-RING_2 PF13639.1 KEY70956.1 - 2.9 7.8 6.7 4.7 7.1 4.6 1.4 1 0 0 1 1 1 0 Ring finger domain DUF4381 PF14316.1 KEY70957.1 - 0.1 12.7 1.6 2.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF3827 PF12877.2 KEY70957.1 - 0.46 8.5 2.3 15 3.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) DUF1764 PF08576.5 KEY70957.1 - 5.6 7.8 6.2 10 6.9 1.3 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) SPRY PF00622.23 KEY70958.1 - 9.3e-07 28.9 0.1 2.9e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 SPRY domain GATA PF00320.22 KEY70959.1 - 2.5e-31 106.6 17.1 3.2e-17 61.5 2.4 2.7 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 KEY70959.1 - 1.1e-06 27.8 1.8 0.015 14.6 0.0 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.1 KEY70959.1 - 0.00023 20.2 5.0 0.18 11.0 0.5 2.7 2 0 0 2 2 2 2 zinc-ribbon domain RRN7 PF11781.3 KEY70959.1 - 0.0003 20.2 6.6 0.13 11.7 0.6 2.6 2 0 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 Zn-ribbon_8 PF09723.5 KEY70959.1 - 0.0028 17.5 1.5 1.1 9.2 0.1 2.7 2 0 0 2 2 2 2 Zinc ribbon domain Ad_cyc_g-alpha PF08509.6 KEY70959.1 - 0.0034 16.6 1.3 0.0091 15.3 0.1 2.5 2 0 0 2 2 2 1 Adenylate cyclase G-alpha binding domain eIF-5_eIF-2B PF01873.12 KEY70959.1 - 0.067 12.8 3.2 1.5 8.4 0.1 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 NMD3 PF04981.8 KEY70959.1 - 0.097 11.7 1.0 1.9 7.5 0.1 2.3 2 0 0 2 2 2 0 NMD3 family DZR PF12773.2 KEY70959.1 - 0.11 12.3 15.5 0.31 10.8 0.6 3.5 2 1 1 3 3 3 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 KEY70959.1 - 0.42 10.4 6.7 0.75 9.6 0.8 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_3 PF13878.1 KEY70959.1 - 0.54 9.8 8.8 5.2 6.7 0.3 4.2 3 1 1 4 4 4 0 zinc-finger of acetyl-transferase ESCO Ribosomal_L32p PF01783.18 KEY70959.1 - 1.1 9.4 9.5 5.5 7.2 1.2 4.1 2 2 0 2 2 2 0 Ribosomal L32p protein family Auto_anti-p27 PF06677.7 KEY70959.1 - 1.9 8.3 5.2 9.4 6.0 0.1 2.8 2 1 1 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Homeobox_KN PF05920.6 KEY70960.1 - 8e-15 54.2 1.4 2e-14 52.9 1.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.11 KEY70960.1 - 4e-11 42.5 0.9 6.8e-05 22.6 0.0 4.3 4 0 0 4 4 4 2 Tc5 transposase DNA-binding domain Homeobox PF00046.24 KEY70960.1 - 6.8e-06 25.6 0.7 1.8e-05 24.2 0.5 1.7 1 0 0 1 1 1 1 Homeobox domain zf-C2H2 PF00096.21 KEY70960.1 - 0.00063 19.9 13.5 0.032 14.5 2.6 4.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY70960.1 - 0.014 15.6 4.2 0.014 15.6 2.9 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger MFS_1 PF07690.11 KEY70964.1 - 1.7e-25 89.5 27.3 1.7e-25 89.5 18.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MTHFR PF02219.12 KEY70966.1 - 2.4e-112 374.7 0.0 3.2e-112 374.2 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase RRM_6 PF14259.1 KEY70967.1 - 1.9e-11 43.7 0.1 4.4e-10 39.3 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEY70967.1 - 4.3e-08 32.6 0.2 4.4e-06 26.2 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY70967.1 - 7.8e-08 32.0 0.0 5.2e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 KEY70967.1 - 6.3e-06 26.1 0.0 1.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.1 KEY70967.1 - 7.7e-06 25.5 0.0 0.046 13.5 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 KEY70967.1 - 0.0011 18.6 5.0 0.002 17.7 3.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ycf1 PF05758.7 KEY70967.1 - 0.016 13.0 0.3 0.017 12.8 0.2 1.1 1 0 0 1 1 1 0 Ycf1 AAA_23 PF13476.1 KEY70967.1 - 0.066 13.5 4.1 0.1 12.9 2.9 1.4 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 KEY70967.1 - 0.97 6.6 18.1 1.3 6.3 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GTP_EFTU PF00009.22 KEY70968.1 - 3.9e-62 209.0 0.3 5.7e-62 208.5 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KEY70968.1 - 3e-38 130.0 0.0 9.6e-38 128.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 KEY70968.1 - 5e-22 77.5 0.0 1.4e-21 76.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KEY70968.1 - 9.2e-13 48.1 2.6 1.6e-12 47.3 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KEY70968.1 - 1.7e-11 43.8 0.0 4.9e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KEY70968.1 - 3e-05 23.9 0.2 6.6e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Sulfatase PF00884.18 KEY70968.1 - 0.033 13.3 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 Sulfatase PAD_M PF08527.5 KEY70968.1 - 0.04 13.3 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain Solute_trans_a PF03619.11 KEY70970.1 - 3.7e-104 347.8 8.6 4.4e-104 347.6 6.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha zf-C2H2_6 PF13912.1 KEY70971.1 - 0.0014 18.4 0.3 0.0014 18.4 0.2 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger Zn_clus PF00172.13 KEY70971.1 - 0.52 10.2 12.6 0.025 14.5 4.7 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-BED PF02892.10 KEY70971.1 - 4.4 7.1 10.9 0.044 13.5 1.0 2.2 2 0 0 2 2 2 0 BED zinc finger Sec5 PF15469.1 KEY70972.1 - 1.8e-36 125.6 0.0 1.6e-34 119.2 0.0 3.0 3 1 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.6 KEY70972.1 - 0.00075 19.2 0.4 0.003 17.3 0.0 2.3 2 0 0 2 2 2 1 Vps51/Vps67 Iso_dh PF00180.15 KEY70973.1 - 1.8e-99 332.9 0.0 2.3e-99 332.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.2 KEY70973.1 - 0.05 13.4 0.0 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif F-box PF00646.28 KEY70974.1 - 0.00047 19.7 0.8 0.00099 18.7 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KEY70975.1 - 1e-07 31.5 0.5 2.8e-07 30.1 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEY70975.1 - 4.9e-06 26.0 0.3 1.2e-05 24.7 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 KEY70975.1 - 0.0022 17.6 0.0 0.0064 16.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like domain Tropomyosin_1 PF12718.2 KEY70975.1 - 0.0035 17.1 2.4 0.013 15.3 0.2 2.3 2 0 0 2 2 2 1 Tropomyosin like IncA PF04156.9 KEY70975.1 - 0.0055 16.3 2.1 0.013 15.1 1.5 1.5 1 0 0 1 1 1 1 IncA protein Spc7 PF08317.6 KEY70975.1 - 0.01 14.5 1.6 0.018 13.7 1.1 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein FliJ PF02050.11 KEY70975.1 - 0.039 13.9 3.0 0.082 12.9 2.1 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein Seryl_tRNA_N PF02403.17 KEY70975.1 - 0.072 13.1 0.7 0.19 11.7 0.5 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 KEY70975.1 - 0.17 10.2 0.7 0.27 9.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Syntaxin PF00804.20 KEY70975.1 - 0.2 11.8 2.1 1.2 9.3 0.6 2.7 2 0 0 2 2 2 0 Syntaxin NPV_P10 PF05531.7 KEY70975.1 - 0.23 11.7 3.4 5.5 7.3 0.1 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FlxA PF14282.1 KEY70975.1 - 0.27 11.1 4.7 1 9.3 3.3 2.0 1 0 0 1 1 1 0 FlxA-like protein BLOC1_2 PF10046.4 KEY70975.1 - 0.51 10.5 2.6 15 5.7 2.1 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fmp27_WPPW PF10359.4 KEY70975.1 - 2.1 6.6 6.5 0.18 10.1 0.4 2.1 3 0 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain Transglut_core PF01841.14 KEY70976.1 - 3.1e-12 46.6 0.0 6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily MFS_1 PF07690.11 KEY70977.1 - 9.8e-45 152.7 37.1 9.8e-45 152.7 25.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY70977.1 - 4.9e-13 48.4 25.8 7.7e-13 47.8 17.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Glycos_transf_4 PF00953.16 KEY70978.1 - 6.3e-30 104.0 9.5 6.3e-30 104.0 6.6 2.0 3 0 0 3 3 3 1 Glycosyl transferase family 4 VPEP PF07589.6 KEY70978.1 - 1.3 8.9 5.7 7 6.7 0.1 3.9 3 0 0 3 3 3 0 PEP-CTERM motif DUF2107 PF09880.4 KEY70978.1 - 2.7 7.9 6.0 1.3 8.9 0.2 3.4 4 1 1 5 5 5 0 Predicted membrane protein (DUF2107) PHD PF00628.24 KEY70979.1 - 2.2e-08 33.6 9.5 2.2e-08 33.6 6.6 2.0 2 0 0 2 2 2 1 PHD-finger SET PF00856.23 KEY70979.1 - 0.0009 19.5 2.7 0.008 16.4 0.0 3.0 3 0 0 3 3 3 1 SET domain E1_DerP2_DerF2 PF02221.10 KEY70980.1 - 1.2e-24 87.0 0.4 1.4e-24 86.8 0.3 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 KEY70980.1 - 0.003 17.5 0.2 0.014 15.4 0.1 1.9 1 1 0 1 1 1 1 ML-like domain ATP-synt_F PF01990.12 KEY70981.1 - 6e-32 109.8 0.1 6.9e-32 109.7 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF2418 PF10332.4 KEY70982.1 - 2.4e-32 111.1 0.0 4.8e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Aconitase PF00330.15 KEY70984.1 - 5.1e-180 598.9 0.0 6.4e-180 598.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KEY70984.1 - 5.9e-44 149.3 0.0 1.2e-43 148.3 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Methyltransf_16 PF10294.4 KEY70985.1 - 5.6e-13 48.7 0.0 1e-11 44.6 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase EF-hand_1 PF00036.27 KEY70986.1 - 3.7e-23 79.0 12.2 5.1e-08 31.6 0.2 4.6 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 KEY70986.1 - 8.5e-22 75.0 3.7 9.4e-06 25.0 0.1 5.1 4 1 1 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 KEY70986.1 - 2.6e-20 72.3 4.2 2.8e-13 49.7 0.5 2.9 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KEY70986.1 - 9.8e-15 53.1 13.6 3.3e-05 23.0 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 KEY70986.1 - 3.7e-13 48.8 12.7 0.00044 19.8 0.7 3.8 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 KEY70986.1 - 8.7e-09 35.0 6.7 0.006 16.3 0.1 4.0 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KEY70986.1 - 0.00014 21.6 0.7 0.041 13.8 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_2 PF09068.6 KEY70986.1 - 0.023 14.7 0.3 3.8 7.5 0.0 3.1 3 1 0 3 3 3 0 EF hand Toprim PF01751.17 KEY70986.1 - 0.03 14.2 0.1 3.8 7.5 0.1 2.2 2 0 0 2 2 2 0 Toprim domain SPARC_Ca_bdg PF10591.4 KEY70986.1 - 0.038 13.9 3.2 0.3 11.1 0.2 3.0 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 KEY70986.1 - 0.063 12.9 2.0 2.5 7.8 0.0 3.3 3 0 0 3 3 3 0 EF hand Hemerythrin PF01814.18 KEY70987.1 - 1.2e-08 35.1 0.5 1.7e-08 34.7 0.4 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF3292 PF11696.3 KEY70987.1 - 0.076 10.8 0.0 0.1 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Cytochrom_B562 PF07361.6 KEY70987.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Cytochrome b562 CDC45 PF02724.9 KEY70988.1 - 1.5e-231 769.8 0.0 3.1e-231 768.7 0.0 1.9 1 1 0 1 1 1 1 CDC45-like protein Methyltransf_23 PF13489.1 KEY70989.1 - 1.1e-14 54.4 0.0 1.6e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY70989.1 - 7.5e-07 29.5 0.0 3.8e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY70989.1 - 3.2e-06 27.7 0.0 3.9e-05 24.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY70989.1 - 5.3e-06 26.0 0.0 6e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY70989.1 - 5.5e-06 26.7 0.0 9.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KEY70989.1 - 0.0018 18.3 0.1 0.0042 17.1 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 KEY70989.1 - 0.016 14.4 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Fungal_trans PF04082.13 KEY70990.1 - 1.6e-17 63.2 0.0 2.5e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY70990.1 - 3.9e-09 36.2 10.2 3.9e-09 36.2 7.0 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KEY70991.1 - 2.2e-34 118.7 59.9 1.7e-32 112.4 41.5 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY70991.1 - 8.9e-11 41.0 15.6 8.9e-11 41.0 10.8 3.3 2 1 2 4 4 4 2 Sugar (and other) transporter JAB PF01398.16 KEY70992.1 - 1.1e-07 31.5 0.0 3.3e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KEY70992.1 - 0.0017 18.4 0.0 0.0057 16.7 0.0 1.8 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function ADH_N PF08240.7 KEY70993.1 - 4.1e-26 90.8 2.4 5.2e-26 90.5 0.7 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY70993.1 - 5.3e-18 64.8 0.7 7.8e-17 61.0 0.5 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 KEY70993.1 - 0.0014 18.5 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 KEY70993.1 - 0.0044 16.4 0.1 0.009 15.4 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 KEY70993.1 - 0.011 15.8 0.1 0.03 14.4 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.16 KEY70993.1 - 0.018 14.8 0.2 0.045 13.5 0.1 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 KEY70993.1 - 0.019 14.5 0.2 0.031 13.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 KEY70993.1 - 0.024 15.2 0.9 0.044 14.3 0.1 2.0 2 1 0 2 2 2 0 Methyltransferase domain ApbA PF02558.11 KEY70993.1 - 0.058 12.8 0.1 0.099 12.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 KEY70993.1 - 0.059 13.1 0.5 0.16 11.7 0.3 1.7 2 0 0 2 2 2 0 ThiF family NAD_binding_8 PF13450.1 KEY70993.1 - 0.063 13.3 2.5 0.22 11.5 0.2 2.7 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Vps5 PF09325.5 KEY70995.1 - 4.5e-13 49.0 0.2 6.4e-13 48.5 0.1 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KEY70995.1 - 1.1e-07 31.5 0.1 2.7e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 PX domain TPR_1 PF00515.23 KEY70995.1 - 0.22 11.1 0.8 0.7 9.5 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat BCIP PF13862.1 KEY70996.1 - 9.4e-65 217.7 0.0 1.2e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein WD40 PF00400.27 KEY70997.1 - 1e-35 120.3 10.7 2.1e-09 36.8 0.3 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Cupin_8 PF13621.1 KEY70997.1 - 5.6e-35 121.0 0.0 1e-34 120.1 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 KEY70997.1 - 1.6e-05 25.1 0.0 0.00081 19.6 0.0 2.9 3 0 0 3 3 3 1 JmjC domain, hydroxylase Nup160 PF11715.3 KEY70997.1 - 2.6e-05 22.5 10.9 0.046 11.8 0.1 4.6 2 2 3 5 5 5 2 Nucleoporin Nup120/160 Cupin_4 PF08007.7 KEY70997.1 - 0.003 16.8 0.0 0.24 10.6 0.0 2.6 2 0 0 2 2 2 1 Cupin superfamily protein Nucleoporin_N PF08801.6 KEY70997.1 - 0.031 13.0 0.2 17 4.0 0.1 3.3 2 2 1 4 4 4 0 Nup133 N terminal like HAUS-augmin3 PF14932.1 KEY70997.1 - 0.33 10.1 2.0 0.55 9.3 1.4 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Seryl_tRNA_N PF02403.17 KEY70997.1 - 1.4 8.9 4.6 2 8.4 0.9 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CENP-Q PF13094.1 KEY70998.1 - 0.0025 17.8 5.1 0.0025 17.8 3.5 3.4 3 1 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF3086 PF11285.3 KEY70998.1 - 0.035 12.9 0.6 0.064 12.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) DUF972 PF06156.8 KEY70998.1 - 0.038 14.3 12.9 0.24 11.7 2.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Atg14 PF10186.4 KEY70998.1 - 0.28 10.1 3.6 0.54 9.1 2.5 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Snapin_Pallidin PF14712.1 KEY70998.1 - 0.94 9.8 7.2 1.3 9.3 0.4 2.5 2 0 0 2 2 2 0 Snapin/Pallidin bZIP_1 PF00170.16 KEY70998.1 - 0.97 9.4 13.5 1.9 8.4 0.5 2.7 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.10 KEY70998.1 - 1.3 8.6 12.1 2.7 7.5 3.9 2.4 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 KEY70998.1 - 3 7.4 12.0 1 8.9 3.7 2.4 2 0 0 2 2 2 0 IncA protein Ax_dynein_light PF10211.4 KEY70998.1 - 3.4 7.4 13.6 7.5 6.3 0.1 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain Rootletin PF15035.1 KEY70998.1 - 3.7 7.4 20.0 0.18 11.7 3.1 3.4 3 1 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion BLOC1_2 PF10046.4 KEY70998.1 - 3.9 7.6 8.0 5.9 7.1 1.6 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_DNA_bd PF12329.3 KEY70998.1 - 7.9 6.3 19.0 4.1 7.2 1.5 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding GRAM PF02893.15 KEY70999.1 - 6.2e-17 60.8 0.0 1.1e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 GRAM domain NOA36 PF06524.7 KEY70999.1 - 1.2 8.3 6.6 0.54 9.4 0.2 2.3 2 0 0 2 2 2 0 NOA36 protein zf-C2H2_4 PF13894.1 KEY71000.1 - 0.014 15.6 15.2 0.44 10.9 0.7 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger Mitofilin PF09731.4 KEY71001.1 - 0.0026 16.4 0.6 0.0026 16.4 0.4 2.4 1 1 1 2 2 2 1 Mitochondrial inner membrane protein DHC_N1 PF08385.7 KEY71002.1 - 1.3e-189 631.4 11.9 1.3e-189 631.4 8.2 4.7 5 1 0 5 5 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 KEY71002.1 - 6.7e-129 429.9 5.7 6.7e-129 429.9 4.0 6.1 6 0 0 6 6 6 2 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 KEY71002.1 - 8.4e-107 357.9 0.0 2.3e-106 356.4 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 KEY71002.1 - 3.9e-77 258.8 0.0 2.6e-76 256.1 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 KEY71002.1 - 1.4e-42 145.1 0.8 2.9e-42 144.0 0.1 2.0 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 KEY71002.1 - 1.3e-41 142.4 8.5 3e-41 141.3 5.9 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.2 KEY71002.1 - 1.2e-39 135.8 0.2 2.1e-38 131.8 0.1 2.7 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_5 PF07728.9 KEY71002.1 - 2.7e-32 111.3 0.0 3e-12 46.4 0.0 6.4 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 KEY71002.1 - 5.5e-21 74.8 0.4 2.6e-19 69.3 0.0 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 KEY71002.1 - 1.1e-14 54.6 0.3 0.017 15.2 0.0 6.1 5 1 0 5 5 4 3 AAA domain AAA PF00004.24 KEY71002.1 - 3e-14 53.3 0.0 0.00095 19.3 0.0 4.9 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEY71002.1 - 1.2e-09 38.9 0.0 0.04 14.7 0.0 5.7 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 KEY71002.1 - 1.4e-09 38.2 12.5 0.22 11.5 0.0 8.9 7 1 0 8 8 8 2 AAA ATPase domain AAA_33 PF13671.1 KEY71002.1 - 1.5e-09 37.8 0.1 0.33 10.8 0.0 5.3 4 0 0 4 4 4 3 AAA domain AAA_18 PF13238.1 KEY71002.1 - 4.8e-09 36.6 0.8 0.048 13.9 0.0 5.9 5 0 0 5 5 5 2 AAA domain T2SE PF00437.15 KEY71002.1 - 6.8e-06 25.1 0.0 0.086 11.7 0.0 3.6 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_19 PF13245.1 KEY71002.1 - 9.1e-06 25.3 0.1 0.89 9.3 0.0 4.6 4 0 0 4 4 4 1 Part of AAA domain AAA_29 PF13555.1 KEY71002.1 - 1.4e-05 24.5 0.0 2 7.9 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain Mg_chelatase PF01078.16 KEY71002.1 - 0.00021 20.5 1.0 0.5 9.4 0.0 3.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 KEY71002.1 - 0.00062 20.0 1.1 6.2 7.1 0.0 4.8 4 0 0 4 4 3 0 ABC transporter IstB_IS21 PF01695.12 KEY71002.1 - 0.0007 19.0 0.6 0.32 10.3 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein RNA_helicase PF00910.17 KEY71002.1 - 0.0095 16.1 0.2 24 5.1 0.0 4.6 4 0 0 4 4 4 0 RNA helicase AAA_25 PF13481.1 KEY71002.1 - 0.0095 15.3 0.3 0.67 9.3 0.0 3.5 4 0 0 4 4 3 1 AAA domain MobB PF03205.9 KEY71002.1 - 0.032 13.9 0.4 11 5.7 0.0 3.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF342 PF03961.8 KEY71002.1 - 9.5 4.5 21.1 4.2 5.6 0.3 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF342) FUSC PF04632.7 KEY71002.1 - 9.8 4.4 5.5 7.5 4.8 1.3 2.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family Peptidase_M13 PF01431.16 KEY71003.1 - 1.3e-14 53.9 0.2 1.7e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M13 HET PF06985.6 KEY71004.1 - 1.4e-23 83.5 0.1 5.1e-23 81.7 0.0 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Zwint PF15556.1 KEY71007.1 - 0.0063 15.8 1.3 0.0086 15.3 0.9 1.1 1 0 0 1 1 1 1 ZW10 interactor GATase_6 PF13522.1 KEY71007.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase domain IncA PF04156.9 KEY71008.1 - 0.13 11.8 6.4 0.18 11.4 4.4 1.2 1 0 0 1 1 1 0 IncA protein DDE_Tnp_1_7 PF13843.1 KEY71009.1 - 5.2e-32 111.2 0.0 1.7e-24 86.5 0.0 2.1 2 0 0 2 2 2 2 Transposase IS4 FA_desaturase PF00487.19 KEY71010.1 - 1.2e-22 80.5 16.0 2.1e-22 79.8 11.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Glyco_trans_2_3 PF13632.1 KEY71010.1 - 0.011 15.4 2.1 0.025 14.3 1.5 1.5 1 0 0 1 1 1 0 Glycosyl transferase family group 2 DUF3375 PF11855.3 KEY71010.1 - 0.034 12.8 0.7 0.046 12.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Annexin PF00191.15 KEY71012.1 - 1.9e-71 235.8 4.4 2.7e-19 68.8 0.0 4.3 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.1 KEY71012.1 - 0.0011 19.1 2.6 9.5 6.5 0.0 3.9 4 0 0 4 4 4 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF3574 PF12098.3 KEY71012.1 - 0.0018 17.7 1.5 15 5.2 0.0 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF3574) TetR_C_6 PF13977.1 KEY71012.1 - 0.086 12.8 1.5 4.8 7.2 0.1 3.1 3 1 0 3 3 3 0 Bacterial transcriptional repressor N_Asn_amidohyd PF14736.1 KEY71012.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase Dehydrin PF00257.14 KEY71013.1 - 3.6 7.8 7.2 29 4.9 5.0 2.4 1 1 0 1 1 1 0 Dehydrin adh_short PF00106.20 KEY71015.1 - 4.7e-09 36.3 0.5 1.9e-08 34.3 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY71015.1 - 0.011 15.3 0.1 0.016 14.8 0.1 1.2 1 0 0 1 1 1 0 KR domain Porphobil_deam PF01379.15 KEY71015.1 - 0.066 12.1 0.0 0.099 11.5 0.0 1.2 1 0 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain NAD_binding_4 PF07993.7 KEY71015.1 - 0.07 12.0 0.1 0.1 11.4 0.1 1.2 1 0 0 1 1 1 0 Male sterility protein Epimerase PF01370.16 KEY71015.1 - 0.086 12.2 0.1 0.46 9.8 0.1 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Abhydrolase_6 PF12697.2 KEY71017.1 - 2.1e-30 106.2 1.0 3.1e-30 105.7 0.4 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY71017.1 - 5.8e-15 55.4 0.0 3.3e-14 52.9 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY71017.1 - 1.2e-14 54.2 0.1 1.5e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KEY71017.1 - 1.9e-05 24.4 0.0 4.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 KEY71017.1 - 5.1e-05 22.2 0.0 7.4e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Ndr PF03096.9 KEY71017.1 - 0.0045 15.5 0.0 0.0067 14.9 0.0 1.2 1 0 0 1 1 1 1 Ndr family Chlorophyllase PF07224.6 KEY71017.1 - 0.021 13.6 0.0 0.029 13.1 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_8 PF06259.7 KEY71017.1 - 0.023 14.2 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_3 PF07859.8 KEY71017.1 - 0.072 12.6 0.0 0.22 11.0 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.11 KEY71018.1 - 4.1e-31 107.9 28.7 4.1e-31 107.9 19.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily WH2 PF02205.15 KEY71020.1 - 1e-09 37.6 0.2 1e-09 37.6 0.1 2.9 3 0 0 3 3 3 1 WH2 motif Ribosomal_L37 PF08561.5 KEY71021.1 - 1.2e-28 98.4 3.2 1.3e-21 75.8 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L37 NDUFB10 PF10249.4 KEY71022.1 - 0.0072 16.4 0.0 0.0085 16.2 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 DUF2889 PF11136.3 KEY71022.1 - 0.11 12.6 0.2 0.2 11.8 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2889) RRM_1 PF00076.17 KEY71023.1 - 2.1e-37 126.5 0.1 1.2e-17 63.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY71023.1 - 1.4e-26 92.2 0.0 5.5e-13 48.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY71023.1 - 5.7e-09 35.6 0.0 8.2e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_C97 PF05903.9 KEY71024.1 - 0.063 13.0 0.0 0.11 12.2 0.0 1.4 2 0 0 2 2 2 0 PPPDE putative peptidase domain Herpes_pp38 PF04846.8 KEY71025.1 - 0.052 12.8 0.2 0.12 11.7 0.2 1.6 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein p450 PF00067.17 KEY71026.1 - 3.9e-75 253.1 0.0 4.7e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3074 PF11274.3 KEY71027.1 - 4e-39 134.1 0.1 8.1e-39 133.1 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) MbeD_MobD PF04899.7 KEY71028.1 - 0.023 14.5 0.1 0.11 12.4 0.1 2.1 1 0 0 1 1 1 0 MbeD/MobD like Aminotran_4 PF01063.14 KEY71028.1 - 0.45 9.9 3.9 0.49 9.8 0.9 2.2 2 1 0 2 2 2 0 Aminotransferase class IV DUF4472 PF14739.1 KEY71028.1 - 7.2 7.1 6.9 0.79 10.2 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) TAFII55_N PF04658.8 KEY71029.1 - 2e-49 167.1 0.5 3.7e-49 166.3 0.0 1.7 2 0 0 2 2 2 1 TAFII55 protein conserved region Kinesin PF00225.18 KEY71031.1 - 1.1e-95 320.1 0.7 1.4e-95 319.8 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain ECIST_Cterm PF14784.1 KEY71031.1 - 0.02 14.8 0.1 8.7 6.3 0.1 2.4 2 0 0 2 2 2 0 C-terminal domain of the ECSIT protein DUF4407 PF14362.1 KEY71031.1 - 4.1 6.2 12.1 9.4 5.0 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Stk19 PF10494.4 KEY71032.1 - 1.6e-44 152.2 0.0 2e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Sulfate_transp PF00916.15 KEY71033.1 - 1.6e-30 106.1 0.4 1.6e-30 106.1 0.3 1.8 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 KEY71033.1 - 6.7e-17 61.0 0.0 1.6e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 KEY71033.1 - 2.3e-11 43.1 0.0 4.3e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain Sld5 PF05916.6 KEY71034.1 - 5.5e-13 49.1 0.0 1e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein EF1_GNE PF00736.14 KEY71035.1 - 4.4e-32 109.6 2.6 7.8e-32 108.8 1.8 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KEY71035.1 - 2.7e-14 53.0 6.9 2.7e-14 53.0 4.8 2.2 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 KEY71035.1 - 1.7e-05 25.1 0.0 4.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KEY71035.1 - 0.00011 22.0 0.3 0.00045 20.1 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Cwf_Cwc_15 PF04889.7 KEY71035.1 - 0.032 13.9 1.5 0.045 13.4 1.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol3_a_NII PF11490.3 KEY71035.1 - 0.26 10.9 4.8 4.7 6.8 0.1 2.3 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II OAD_gamma PF04277.8 KEY71035.1 - 1.9 8.8 4.4 1.1 9.6 1.5 1.8 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Proteasom_Rpn13 PF04683.8 KEY71036.1 - 1.7e-27 95.3 0.0 2.5e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor L27_2 PF09045.5 KEY71036.1 - 0.0013 18.2 0.1 0.0027 17.2 0.1 1.5 1 0 0 1 1 1 1 L27_2 CTP_synth_N PF06418.9 KEY71037.1 - 2.6e-115 384.2 0.0 3.6e-115 383.7 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KEY71037.1 - 2.9e-49 167.1 0.0 4.3e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KEY71037.1 - 2.9e-05 23.6 0.0 6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 KEY71037.1 - 0.0025 17.2 0.0 0.016 14.6 0.0 2.0 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2469 PF10611.4 KEY71037.1 - 0.0095 16.2 0.1 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2469) RRM_1 PF00076.17 KEY71038.1 - 5.6e-14 51.5 0.0 8e-07 28.6 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY71038.1 - 4.9e-13 48.8 0.1 7.9e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY71038.1 - 1.1e-06 28.4 0.0 7e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 5-nucleotidase PF06189.7 KEY71040.1 - 0.12 11.1 0.3 0.23 10.2 0.2 1.5 1 0 0 1 1 1 0 5'-nucleotidase DUF3405 PF11885.3 KEY71041.1 - 2.2e-204 679.3 0.0 2.7e-204 679.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) EMP24_GP25L PF01105.19 KEY71042.1 - 1.4e-42 145.5 0.0 1.7e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Arf PF00025.16 KEY71043.1 - 2.5e-80 267.8 0.3 2.8e-80 267.6 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KEY71043.1 - 1.6e-14 53.5 0.0 2e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KEY71043.1 - 2.4e-13 49.8 0.0 2.6e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KEY71043.1 - 2.2e-12 46.3 2.0 2.5e-09 36.3 0.5 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KEY71043.1 - 3.6e-11 42.6 0.0 4.3e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KEY71043.1 - 1.2e-08 35.4 0.0 1.8e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KEY71043.1 - 2.5e-06 27.4 0.0 3.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KEY71043.1 - 0.0089 15.1 0.7 0.02 13.9 0.5 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 KEY71043.1 - 0.012 15.0 0.2 0.093 12.1 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KEY71043.1 - 0.04 13.7 0.2 0.097 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.9 KEY71044.1 - 3.6e-44 150.6 0.0 2.4e-43 148.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 KEY71044.1 - 1.9e-25 88.5 1.1 4.1e-25 87.4 0.1 2.2 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KEY71044.1 - 5.8e-19 68.5 0.0 6.2e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEY71044.1 - 1.6e-12 47.3 0.1 7.4e-09 35.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEY71044.1 - 1.7e-09 37.9 0.3 0.00055 20.0 0.0 3.2 2 2 1 3 3 2 2 AAA domain AAA_16 PF13191.1 KEY71044.1 - 2.2e-09 37.5 12.8 0.00078 19.4 0.0 5.1 4 2 0 6 6 5 3 AAA ATPase domain Sigma54_activat PF00158.21 KEY71044.1 - 1.8e-06 27.5 0.4 0.00045 19.7 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 KEY71044.1 - 3.6e-05 24.5 4.0 0.022 15.5 0.1 3.7 3 1 0 3 3 3 1 AAA domain NACHT PF05729.7 KEY71044.1 - 5.3e-05 22.9 0.1 0.41 10.2 0.0 2.9 3 0 0 3 3 2 2 NACHT domain AAA_14 PF13173.1 KEY71044.1 - 6.8e-05 22.7 0.0 0.16 11.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KEY71044.1 - 0.00022 20.8 0.0 0.023 14.4 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 KEY71044.1 - 0.00034 20.3 9.2 0.84 9.2 0.0 4.3 3 2 1 4 4 3 2 Archaeal ATPase IstB_IS21 PF01695.12 KEY71044.1 - 0.00082 18.8 0.0 0.82 9.0 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein MobB PF03205.9 KEY71044.1 - 0.0014 18.3 0.0 0.26 10.9 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KEY71044.1 - 0.0021 18.3 1.1 0.25 11.6 0.0 3.3 3 0 0 3 3 3 1 ABC transporter Mg_chelatase PF01078.16 KEY71044.1 - 0.0049 16.0 0.1 1.5 7.9 0.0 3.0 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KEY71044.1 - 0.0055 16.8 0.0 0.94 9.6 0.0 3.0 2 1 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 KEY71044.1 - 0.0058 16.9 8.5 0.15 12.4 0.0 3.3 4 0 0 4 4 3 2 AAA domain AAA_33 PF13671.1 KEY71044.1 - 0.0067 16.3 0.0 5.5 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KEY71044.1 - 0.0087 16.0 0.6 6.7 6.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.17 KEY71044.1 - 0.012 15.0 0.0 0.47 9.8 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 KEY71044.1 - 0.014 14.8 0.1 0.69 9.2 0.0 3.2 2 2 0 2 2 2 0 AAA-like domain DUF258 PF03193.11 KEY71044.1 - 0.022 13.9 0.0 3.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 UvrD-helicase PF00580.16 KEY71044.1 - 0.024 13.9 2.7 0.4 9.9 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF815 PF05673.8 KEY71044.1 - 0.024 13.5 1.2 0.79 8.6 0.3 3.3 3 2 0 3 3 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 KEY71044.1 - 0.025 13.6 0.2 1.1 8.3 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin AAA_25 PF13481.1 KEY71044.1 - 0.027 13.8 2.1 2.5 7.4 0.0 3.0 3 1 0 3 3 2 0 AAA domain ResIII PF04851.10 KEY71044.1 - 0.03 14.1 2.7 6.2 6.6 0.0 3.2 3 1 1 4 4 3 0 Type III restriction enzyme, res subunit PhoH PF02562.11 KEY71044.1 - 0.032 13.4 0.1 0.7 9.0 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein IncA PF04156.9 KEY71044.1 - 0.037 13.6 8.4 0.022 14.3 4.3 1.7 2 0 0 2 2 1 0 IncA protein PduV-EutP PF10662.4 KEY71044.1 - 0.045 13.2 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 KEY71044.1 - 0.06 13.8 0.1 4.4 7.8 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 KEY71044.1 - 0.073 12.6 0.0 2 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Filament PF00038.16 KEY71044.1 - 0.086 12.2 10.6 0.36 10.2 7.3 2.0 1 1 0 1 1 1 0 Intermediate filament protein OEP PF02321.13 KEY71044.1 - 0.15 11.6 4.1 0.39 10.2 2.8 1.7 1 0 0 1 1 1 0 Outer membrane efflux protein Atg14 PF10186.4 KEY71044.1 - 0.24 10.2 7.8 0.55 9.1 5.4 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 KEY71044.1 - 0.25 11.0 10.4 0.52 9.9 7.2 1.5 1 0 0 1 1 1 0 Mnd1 family CENP-F_leu_zip PF10473.4 KEY71044.1 - 0.27 11.0 12.9 1.2 9.0 9.0 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 KEY71044.1 - 0.49 9.3 6.7 0.91 8.5 4.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 KEY71044.1 - 5.2 6.6 9.9 13 5.3 3.4 2.8 1 1 1 2 2 2 0 Septum formation initiator Seryl_tRNA_N PF02403.17 KEY71044.1 - 6.5 6.8 13.7 4.6 7.3 7.2 2.6 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain Ribosomal_L6e PF01159.14 KEY71045.1 - 3.9e-37 126.7 0.5 3.9e-37 126.7 0.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e Peptidase_M49 PF03571.10 KEY71046.1 - 1e-231 769.8 0.0 1.3e-231 769.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 AAA_33 PF13671.1 KEY71047.1 - 3.9e-13 49.5 0.0 6.2e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 KEY71047.1 - 5.7e-12 45.7 0.0 7e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 KEY71047.1 - 4.1e-10 40.5 0.0 5.2e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEY71047.1 - 1.2e-08 35.2 0.0 2.5e-08 34.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 KEY71047.1 - 2e-05 23.5 0.0 2.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 KEY71047.1 - 3.7e-05 23.9 0.0 9.1e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEY71047.1 - 0.00017 21.6 0.0 0.00039 20.5 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KEY71047.1 - 0.00055 19.9 0.0 0.0009 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain CoaE PF01121.15 KEY71047.1 - 0.0014 18.0 0.1 0.0043 16.4 0.0 1.9 3 0 0 3 3 2 1 Dephospho-CoA kinase RNA_helicase PF00910.17 KEY71047.1 - 0.0019 18.3 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 KEY71047.1 - 0.0022 18.0 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 KEY71047.1 - 0.0023 17.8 0.0 0.011 15.6 0.0 2.0 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_14 PF13173.1 KEY71047.1 - 0.0025 17.6 0.0 0.0051 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KEY71047.1 - 0.0063 15.7 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 KEY71047.1 - 0.0071 16.6 0.0 0.022 15.0 0.0 2.0 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.7 KEY71047.1 - 0.0072 15.9 0.1 0.018 14.7 0.0 1.8 2 1 0 2 2 2 1 NACHT domain APS_kinase PF01583.15 KEY71047.1 - 0.0078 15.8 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase Viral_helicase1 PF01443.13 KEY71047.1 - 0.014 14.9 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PRK PF00485.13 KEY71047.1 - 0.015 14.8 0.0 0.032 13.7 0.0 1.5 2 0 0 2 2 1 0 Phosphoribulokinase / Uridine kinase family DUF2075 PF09848.4 KEY71047.1 - 0.02 13.8 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.1 KEY71047.1 - 0.024 14.1 0.0 0.063 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KEY71047.1 - 0.028 13.5 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 KEY71047.1 - 0.029 14.1 0.0 0.072 12.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 KEY71047.1 - 0.046 13.4 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KEY71047.1 - 0.063 12.6 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KEY71047.1 - 0.08 11.7 0.0 0.27 10.0 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.10 KEY71047.1 - 0.091 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 NTPase Arch_ATPase PF01637.13 KEY71047.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_PrkA PF08298.6 KEY71047.1 - 0.13 10.9 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain G-alpha PF00503.15 KEY71047.1 - 0.14 10.7 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit 2-oxoacid_dh PF00198.18 KEY71048.1 - 2.1e-76 256.2 0.0 2.7e-76 255.8 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KEY71048.1 - 2.4e-15 55.9 0.0 4.5e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KEY71048.1 - 1e-12 47.4 0.0 2.9e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain BEX PF04538.7 KEY71048.1 - 0.089 13.0 0.4 0.25 11.5 0.0 1.8 2 0 0 2 2 2 0 Brain expressed X-linked like family ATP-synt_10 PF05176.9 KEY71049.1 - 1.9e-82 276.3 0.0 2.4e-82 276.0 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein V-SNARE_C PF12352.3 KEY71050.1 - 6.4e-13 48.5 8.2 6.6e-13 48.5 0.2 3.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Spc7 PF08317.6 KEY71050.1 - 0.041 12.5 5.3 0.05 12.2 3.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 KEY71050.1 - 3.5 6.4 10.9 0.59 9.0 5.3 1.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Ribosomal_L29 PF00831.18 KEY71051.1 - 3.3e-17 61.9 0.6 7.9e-17 60.6 0.4 1.7 1 0 0 1 1 1 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 KEY71051.1 - 0.15 12.3 2.6 0.18 12.0 1.8 1.2 1 0 0 1 1 1 0 Ribosomal protein S9/S16 zf-H2C2_2 PF13465.1 KEY71052.1 - 7.7e-16 57.5 38.7 1.4e-06 28.2 1.3 7.2 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 KEY71052.1 - 1.2e-06 28.4 57.0 0.0095 16.2 1.0 8.5 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY71052.1 - 3.1e-06 27.1 68.5 3.1e-05 24.0 1.8 8.8 9 0 0 9 9 9 5 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KEY71052.1 - 2.3e-05 24.1 10.6 0.0063 16.3 0.2 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KEY71052.1 - 0.091 12.4 0.2 0.091 12.4 0.1 4.1 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 KEY71052.1 - 0.9 9.7 19.4 0.37 11.0 1.0 4.8 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEY71052.1 - 0.98 9.7 9.5 4.3 7.6 0.1 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type WLM PF08325.5 KEY71053.1 - 1.7 8.4 4.3 0.41 10.5 0.2 1.8 2 0 0 2 2 2 0 WLM domain DEAD PF00270.24 KEY71054.1 - 2.4e-44 150.8 0.0 1.4e-43 148.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY71054.1 - 3e-24 84.6 0.0 8.8e-24 83.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KEY71054.1 - 0.048 12.4 0.0 0.083 11.6 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain HCNGP PF07818.8 KEY71055.1 - 8.2e-23 80.2 0.0 1.3e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 HCNGP-like protein DUF3712 PF12505.3 KEY71056.1 - 4.5e-21 75.1 0.5 1.7e-20 73.3 0.0 2.1 3 1 0 3 3 3 1 Protein of unknown function (DUF3712) FMN_dh PF01070.13 KEY71057.1 - 6.9e-102 340.9 0.0 8.4e-102 340.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KEY71057.1 - 1.8e-21 75.6 0.0 3.7e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KEY71057.1 - 1.6e-07 30.6 0.1 2.5e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KEY71057.1 - 4.7e-07 29.0 0.2 0.00023 20.1 0.1 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.16 KEY71057.1 - 0.008 15.1 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.16 KEY71057.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein ATP11 PF06644.6 KEY71057.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 ATP11 protein NMO PF03060.10 KEY71057.1 - 0.044 12.9 0.3 0.084 11.9 0.2 1.4 1 1 0 1 1 1 0 Nitronate monooxygenase Ribul_P_3_epim PF00834.14 KEY71057.1 - 0.17 10.9 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family HSCB_C PF07743.8 KEY71058.1 - 1.3e-15 57.6 6.2 1.3e-15 57.6 4.3 1.6 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 KEY71058.1 - 7.7e-09 35.1 0.0 2e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 DnaJ domain DUF1746 PF08508.5 KEY71060.1 - 8.7e-30 103.0 1.6 1.2e-29 102.5 1.1 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) RTC_insert PF05189.8 KEY71061.1 - 4.1e-31 107.0 0.0 7.3e-31 106.2 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.16 KEY71061.1 - 6.3e-31 106.9 0.0 8.7e-31 106.4 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase PPR_2 PF13041.1 KEY71062.1 - 1.5e-13 50.4 0.6 1.7e-08 34.3 0.0 5.2 6 0 0 6 6 6 1 PPR repeat family PPR_3 PF13812.1 KEY71062.1 - 0.00014 21.8 1.7 48 4.5 0.0 6.2 7 0 0 7 7 7 0 Pentatricopeptide repeat domain TPR_19 PF14559.1 KEY71062.1 - 0.0012 19.1 0.1 0.45 10.8 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEY71062.1 - 0.0085 16.4 0.5 44 4.8 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.15 KEY71062.1 - 0.038 13.9 7.9 0.29 11.2 0.0 5.3 7 0 0 7 7 7 0 PPR repeat PPR_1 PF12854.2 KEY71062.1 - 0.056 12.9 0.4 48 3.5 0.0 4.0 4 0 0 4 4 4 0 PPR repeat ATP-synt_B PF00430.13 KEY71062.1 - 0.18 11.6 4.5 0.48 10.2 3.1 1.7 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) TPR_14 PF13428.1 KEY71062.1 - 0.23 12.1 3.8 25 5.8 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEY71062.1 - 0.76 9.7 4.3 7.3 6.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Bromo_TP PF07524.8 KEY71063.1 - 2e-09 37.0 0.0 3.5e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 KEY71063.1 - 0.002 17.8 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Dockerin_1 PF00404.13 KEY71063.1 - 0.18 11.5 1.9 0.5 10.1 0.1 2.3 2 0 0 2 2 2 0 Dockerin type I repeat NuA4 PF09340.5 KEY71064.1 - 1.7e-23 82.0 0.6 2.6e-23 81.4 0.0 1.5 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 PWI PF01480.12 KEY71065.1 - 2.4e-29 101.2 0.2 3.9e-29 100.5 0.1 1.3 1 0 0 1 1 1 1 PWI domain GRASP55_65 PF04495.9 KEY71066.1 - 2e-06 27.8 0.0 4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 KEY71066.1 - 1.6e-05 24.6 0.0 2.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 KEY71066.1 - 0.0015 18.7 0.0 0.0023 18.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Ras PF00071.17 KEY71067.1 - 5.7e-49 165.6 0.0 7.1e-49 165.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEY71067.1 - 5e-15 56.0 0.0 1e-14 55.0 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 KEY71067.1 - 1.2e-10 40.8 0.0 1.7e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 KEY71067.1 - 0.0005 20.2 0.1 0.0043 17.1 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 KEY71067.1 - 0.0025 16.9 0.0 0.0033 16.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 KEY71067.1 - 0.0064 15.8 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_24 PF13479.1 KEY71067.1 - 0.059 12.9 0.4 0.1 12.1 0.3 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KEY71067.1 - 0.08 12.8 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 KEY71067.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KEY71067.1 - 0.082 13.0 0.5 0.45 10.6 0.1 2.1 2 1 0 3 3 3 0 AAA domain G-alpha PF00503.15 KEY71067.1 - 0.089 11.4 1.8 1.8 7.1 0.1 2.5 2 1 1 3 3 3 0 G-protein alpha subunit MMR_HSR1 PF01926.18 KEY71067.1 - 0.14 12.1 0.1 0.3 11.0 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Homeobox PF00046.24 KEY71068.1 - 3.4e-13 48.9 3.6 5.8e-13 48.2 1.8 2.0 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KEY71068.1 - 0.021 14.5 0.1 0.059 13.0 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain NAD_kinase PF01513.16 KEY71069.1 - 3.3e-72 242.6 0.0 4.4e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Fer2_3 PF13085.1 KEY71069.1 - 0.032 14.0 0.0 0.18 11.6 0.0 2.2 2 1 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain RNase_PH PF01138.16 KEY71071.1 - 1.8e-12 47.6 0.0 3.2e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KEY71071.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 PTPA PF03095.10 KEY71072.1 - 2.9e-109 364.8 0.0 3.4e-109 364.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Carb_kinase PF01256.12 KEY71074.1 - 2.9e-53 180.6 0.0 3.8e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 KEY71074.1 - 0.031 13.4 0.0 0.062 12.4 0.0 1.6 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase ATP-synt_ab PF00006.20 KEY71075.1 - 6.7e-72 241.4 0.0 1.1e-71 240.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KEY71075.1 - 2.3e-26 92.4 0.7 8.1e-26 90.7 0.2 2.3 2 1 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KEY71075.1 - 1e-15 57.6 2.7 2.7e-15 56.3 1.9 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KEY71075.1 - 0.0023 17.8 1.7 0.0069 16.2 1.0 2.0 2 1 0 2 2 2 1 HAS barrel domain Ribosomal_L5_C PF00673.16 KEY71076.1 - 4.6e-23 80.7 0.0 6.6e-23 80.2 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KEY71076.1 - 1.6e-21 75.8 0.1 4.4e-21 74.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.17 KEY71077.1 - 6.6e-16 57.6 0.0 9.2e-16 57.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain Fungal_trans_2 PF11951.3 KEY71078.1 - 1e-06 27.6 2.6 5.7e-05 21.8 0.2 2.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain EFG_II PF14492.1 KEY71078.1 - 0.11 12.3 0.1 0.36 10.6 0.1 1.8 1 0 0 1 1 1 0 Elongation Factor G, domain II DnaJ PF00226.26 KEY71079.1 - 1.7e-09 37.2 0.2 3e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Gly-zipper_OmpA PF13436.1 KEY71079.1 - 0.0091 15.6 0.7 0.02 14.5 0.5 1.6 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain DUF456 PF04306.8 KEY71079.1 - 0.016 15.2 0.3 0.022 14.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) ProRS-C_1 PF09180.6 KEY71079.1 - 0.096 12.6 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal Rick_17kDa_Anti PF05433.10 KEY71079.1 - 0.91 9.2 10.0 1.8 8.3 6.9 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain Clr5 PF14420.1 KEY71080.1 - 2.1e-12 46.7 0.2 4.1e-12 45.7 0.2 1.5 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 KEY71080.1 - 3.2e-08 33.3 5.7 1.1e-06 28.4 0.3 3.9 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEY71080.1 - 2.9e-05 23.6 2.8 0.038 13.9 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEY71080.1 - 0.00011 22.4 7.5 0.47 11.2 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 KEY71080.1 - 0.00027 20.7 11.8 0.01 15.7 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEY71080.1 - 0.00044 19.8 2.5 0.037 13.8 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEY71080.1 - 0.0052 17.4 7.1 0.0057 17.2 0.7 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEY71080.1 - 0.015 15.0 0.1 0.015 15.0 0.1 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEY71080.1 - 0.037 13.6 0.5 0.19 11.3 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KEY71080.1 - 0.058 13.7 1.5 0.12 12.6 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Phage_X PF05155.10 KEY71080.1 - 0.063 13.2 0.0 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 Phage X family TPR_21 PF09976.4 KEY71080.1 - 0.082 12.8 0.6 0.16 11.9 0.4 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEY71080.1 - 0.14 12.7 2.1 1.7 9.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KEY71080.1 - 0.85 10.2 7.2 2.2 8.9 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat PITH PF06201.8 KEY71081.1 - 1.2e-39 135.4 0.0 1.6e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 KEY71081.1 - 5.6e-22 77.3 0.0 9.8e-22 76.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KEY71081.1 - 2.2e-05 24.4 0.1 0.00018 21.5 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KEY71081.1 - 4.9e-05 22.8 0.0 9.4e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KEY71081.1 - 0.00017 21.7 0.1 0.00063 19.9 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain HyaE PF07449.6 KEY71081.1 - 0.028 14.3 0.0 0.077 12.9 0.0 1.7 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Redoxin PF08534.5 KEY71081.1 - 0.045 13.3 0.5 0.62 9.5 0.1 2.2 1 1 1 2 2 2 0 Redoxin AhpC-TSA PF00578.16 KEY71081.1 - 0.11 12.1 0.3 15 5.2 0.0 2.3 1 1 1 2 2 2 0 AhpC/TSA family BTB PF00651.26 KEY71082.1 - 0.0077 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Chaperone_III PF07824.7 KEY71082.1 - 0.045 13.6 0.1 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Type III secretion chaperone domain RhoGAP PF00620.22 KEY71084.1 - 7.3e-42 142.5 0.3 1.5e-41 141.5 0.2 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 KEY71084.1 - 4.4e-10 39.6 0.0 8.9e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KEY71084.1 - 6e-07 29.7 0.0 1.3e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain GOLGA2L5 PF15070.1 KEY71084.1 - 0.0025 16.3 0.3 0.0047 15.4 0.2 1.3 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 PspA_IM30 PF04012.7 KEY71084.1 - 0.006 15.9 1.2 0.011 15.0 0.8 1.3 1 0 0 1 1 1 1 PspA/IM30 family PH_8 PF15409.1 KEY71084.1 - 0.026 14.6 0.0 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3450 PF11932.3 KEY71084.1 - 0.031 13.5 0.3 0.061 12.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Rabaptin PF03528.10 KEY71084.1 - 0.62 10.0 5.1 0.096 12.6 0.3 1.9 2 0 0 2 2 2 0 Rabaptin Zn_clus PF00172.13 KEY71085.1 - 2.4e-05 24.1 7.5 4.9e-05 23.1 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WLM PF08325.5 KEY71087.1 - 1.4e-48 165.2 1.9 1.5e-48 165.1 0.0 1.9 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.12 KEY71087.1 - 7.9e-08 32.3 2.2 1.9e-07 31.0 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function DUF45 zf-RanBP PF00641.13 KEY71087.1 - 6.5 5.9 12.0 2 7.5 2.7 2.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Sulfate_transp PF00916.15 KEY71088.1 - 8.1e-74 248.1 8.5 1.2e-73 247.5 5.9 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KEY71088.1 - 1.5e-31 107.9 2.8 1.5e-31 107.9 1.9 3.1 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KEY71088.1 - 2.1e-08 33.6 0.0 4.1e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain TMEM107 PF14995.1 KEY71088.1 - 2 8.5 8.0 0.28 11.3 2.2 2.0 2 0 0 2 2 2 0 Transmembrane protein RabGAP-TBC PF00566.13 KEY71089.1 - 1.5e-32 112.7 0.0 4.3e-32 111.3 0.0 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain HlyIII PF03006.15 KEY71090.1 - 1.3e-54 185.0 20.2 1.5e-54 184.7 14.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related SPC12 PF06645.8 KEY71090.1 - 0.057 13.2 0.2 0.057 13.2 0.1 1.9 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) TelA PF05816.6 KEY71090.1 - 0.18 10.5 0.0 0.25 9.9 0.0 1.1 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) DUF883 PF05957.8 KEY71090.1 - 6.3 7.2 8.5 7.9 6.9 1.3 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) FimP PF09766.4 KEY71091.1 - 1.6e-25 89.9 10.1 2.2e-25 89.5 7.0 1.1 1 0 0 1 1 1 1 Fms-interacting protein K-box PF01486.12 KEY71091.1 - 0.018 14.8 0.3 0.018 14.8 0.2 3.4 2 2 1 3 3 3 0 K-box region Flagellin_N PF00669.15 KEY71091.1 - 0.045 13.5 3.8 2.6 7.8 0.5 2.1 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region Cob_adeno_trans PF01923.13 KEY71091.1 - 0.047 13.4 5.0 0.54 10.0 3.1 2.1 1 1 0 1 1 1 0 Cobalamin adenosyltransferase PVL_ORF50 PF07768.6 KEY71091.1 - 0.054 13.4 2.5 0.099 12.6 1.5 1.8 2 0 0 2 2 2 0 PVL ORF-50-like family Methyltransf_21 PF05050.7 KEY71091.1 - 0.096 12.6 0.1 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase FkbM domain CENP-H PF05837.7 KEY71091.1 - 0.31 11.2 6.7 1.4 9.1 2.1 2.4 2 1 0 2 2 2 0 Centromere protein H (CENP-H) CENP-F_leu_zip PF10473.4 KEY71091.1 - 0.6 9.9 14.3 1.1 9.0 5.0 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FUSC PF04632.7 KEY71091.1 - 0.95 7.8 9.8 1.2 7.5 6.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Pinin_SDK_memA PF04696.8 KEY71091.1 - 1.5 8.4 11.8 0.38 10.3 5.3 2.0 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF3450 PF11932.3 KEY71091.1 - 2.6 7.2 11.6 3.2 6.9 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF87 PF01935.12 KEY71091.1 - 2.7 7.7 5.4 5 6.8 3.7 1.6 1 1 0 1 1 1 0 Domain of unknown function DUF87 DUF349 PF03993.7 KEY71091.1 - 5.8 7.1 11.1 0.78 9.9 4.3 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) PP28 PF10252.4 KEY71091.1 - 8.8 6.4 14.6 0.26 11.3 4.4 2.3 2 1 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 MOSC_N PF03476.11 KEY71092.1 - 9.8e-23 80.1 0.0 2.3e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KEY71092.1 - 6e-18 64.5 0.0 1.1e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.14 KEY71092.1 - 9e-18 64.1 0.0 1.1e-16 60.5 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class-V Glyco_trans_2_3 PF13632.1 KEY71093.1 - 3.5e-15 56.2 1.1 3.5e-15 56.2 0.8 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DUF4066 PF13278.1 KEY71094.1 - 1.6e-11 43.7 0.0 2.3e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KEY71094.1 - 4.4e-05 22.9 0.0 6.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family AICARFT_IMPCHas PF01808.13 KEY71095.1 - 7.3e-112 373.5 0.0 9.5e-112 373.1 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 KEY71095.1 - 1.2e-23 82.8 0.0 2.4e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Pkinase PF00069.20 KEY71096.1 - 3.6e-40 137.7 0.1 1.1e-31 109.8 0.0 3.5 2 1 0 2 2 2 2 Protein kinase domain FKBP_C PF00254.23 KEY71096.1 - 1.7e-30 104.8 0.0 4.2e-30 103.6 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase_Tyr PF07714.12 KEY71096.1 - 1.4e-16 60.3 0.0 9.5e-16 57.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY71096.1 - 0.028 13.4 0.0 0.056 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Exo_endo_phos PF03372.18 KEY71097.1 - 2.8e-20 73.2 1.4 3.9e-20 72.8 1.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ABM PF03992.11 KEY71098.1 - 2.1e-07 30.8 1.0 0.0006 19.7 0.1 2.5 3 0 0 3 3 3 2 Antibiotic biosynthesis monooxygenase Dabb PF07876.7 KEY71098.1 - 0.048 14.0 0.0 0.14 12.5 0.0 1.7 2 0 0 2 2 2 0 Stress responsive A/B Barrel Domain KH_1 PF00013.24 KEY71099.1 - 1.7e-39 133.2 6.6 1.8e-16 59.4 0.4 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KEY71099.1 - 3.6e-31 106.2 11.9 4.8e-12 45.2 1.9 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KEY71099.1 - 1.8e-12 46.6 4.8 0.0031 17.0 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KEY71099.1 - 1.4e-05 24.6 1.0 0.48 10.0 0.0 3.5 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 KEY71099.1 - 0.002 17.8 6.2 0.7 9.7 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain CENP-K PF11802.3 KEY71100.1 - 1.1e-08 34.7 0.2 0.00044 19.5 0.0 2.3 2 1 0 2 2 2 2 Centromere-associated protein K Med9 PF07544.8 KEY71100.1 - 0.16 11.7 3.8 7.9 6.2 0.0 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Fzo_mitofusin PF04799.8 KEY71100.1 - 0.17 11.2 2.2 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 fzo-like conserved region Atg14 PF10186.4 KEY71100.1 - 0.5 9.2 6.1 0.98 8.3 4.2 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 M PF02370.11 KEY71100.1 - 1 9.9 8.3 4 8.1 0.4 3.9 3 0 0 3 3 3 0 M protein repeat Med4 PF10018.4 KEY71100.1 - 1.6 8.1 7.4 0.48 9.8 0.2 2.6 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 OmpH PF03938.9 KEY71100.1 - 2 8.3 12.6 3.8 7.4 2.3 2.8 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) DUF4200 PF13863.1 KEY71100.1 - 2.5 8.0 10.7 5.7 6.9 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Mnd1 PF03962.10 KEY71100.1 - 5 6.7 11.3 8.4 6.0 2.5 2.6 3 0 0 3 3 3 0 Mnd1 family Phos_pyr_kin PF08543.7 KEY71101.1 - 2.1e-06 27.1 0.0 4.8e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 KEY71101.1 - 3.1e-06 26.5 0.2 0.0019 17.3 0.0 2.7 2 1 0 2 2 2 2 pfkB family carbohydrate kinase PCNA_N PF00705.13 KEY71102.1 - 6.4e-51 171.1 0.5 1.2e-50 170.2 0.3 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 KEY71102.1 - 7e-50 168.2 0.0 1.3e-49 167.3 0.0 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 KEY71102.1 - 6e-08 32.1 0.0 7e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 KEY71102.1 - 0.00035 19.6 0.0 0.0068 15.3 0.0 2.1 1 1 1 2 2 2 1 Hus1-like protein Vezatin PF12632.2 KEY71103.1 - 1.2e-49 168.6 0.0 1.7e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes IncA PF04156.9 KEY71105.1 - 0.018 14.6 6.7 6.2 6.3 8.3 2.6 2 0 0 2 2 2 0 IncA protein DUF3138 PF11336.3 KEY71105.1 - 5.2 5.1 0.7 16 3.5 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) p450 PF00067.17 KEY71106.1 - 1.7e-71 241.1 0.0 2e-71 240.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-RING_2 PF13639.1 KEY71107.1 - 9.8e-11 41.3 5.2 1.6e-10 40.6 3.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEY71107.1 - 1.5e-08 34.6 1.6 2.4e-08 33.9 1.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KEY71107.1 - 2.9e-05 24.0 6.5 5.4e-05 23.1 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY71107.1 - 5.4e-05 22.8 3.8 8.4e-05 22.2 2.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KEY71107.1 - 0.00011 21.9 0.8 0.0002 21.1 0.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 KEY71107.1 - 0.00077 19.0 4.5 0.0013 18.2 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEY71107.1 - 0.0014 18.2 3.3 0.0022 17.5 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KEY71107.1 - 0.0035 17.0 1.1 0.0073 15.9 0.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 KEY71107.1 - 0.1 12.5 3.5 1.3 9.0 2.4 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_6 PF14835.1 KEY71107.1 - 0.13 12.0 0.2 0.31 10.8 0.2 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 KEY71107.1 - 0.17 11.4 1.4 0.32 10.5 1.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Baculo_RING PF05883.6 KEY71107.1 - 0.36 10.6 1.2 0.59 9.9 0.8 1.2 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Cullin PF00888.17 KEY71108.1 - 3.1e-54 184.5 0.1 5.6e-54 183.6 0.1 1.4 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 KEY71108.1 - 5.6e-19 68.1 0.0 1.1e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 zf-C2H2_4 PF13894.1 KEY71109.1 - 0.00019 21.5 7.1 0.26 11.7 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY71109.1 - 0.0067 16.7 9.0 0.22 11.9 0.4 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KEY71109.1 - 0.074 13.3 0.4 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 KEY71109.1 - 0.24 11.3 2.8 11 6.1 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Pkr1 PF08636.5 KEY71110.1 - 3.1e-34 116.8 6.1 3.9e-34 116.5 4.3 1.1 1 0 0 1 1 1 1 ER protein Pkr1 FHIPEP PF00771.15 KEY71110.1 - 0.15 10.3 0.0 0.17 10.1 0.0 1.0 1 0 0 1 1 1 0 FHIPEP family MFS_2 PF13347.1 KEY71111.1 - 2.8e-12 45.7 8.4 2.8e-12 45.7 5.8 2.4 3 0 0 3 3 3 1 MFS/sugar transport protein DUF3278 PF11683.3 KEY71111.1 - 0.47 10.4 1.7 2.4 8.1 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3278) MFS_1_like PF12832.2 KEY71111.1 - 2 8.2 0.0 2 8.2 0.0 4.4 5 0 0 5 5 5 0 MFS_1 like family RhoGEF PF00621.15 KEY71112.1 - 8.1e-34 117.0 0.1 1.8e-33 115.9 0.1 1.6 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 KEY71112.1 - 6.9e-12 45.3 0.2 1.7e-11 44.0 0.1 1.6 1 0 0 1 1 1 1 BAR domain Telomerase_RBD PF12009.3 KEY71113.1 - 2.7e-40 137.4 2.9 9.4e-40 135.6 0.6 2.4 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 KEY71113.1 - 2.2e-14 53.3 0.0 1.6e-13 50.5 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MBOAT_2 PF13813.1 KEY71114.1 - 1.8e-14 53.5 3.8 5.3e-14 52.0 2.6 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Zn_clus PF00172.13 KEY71115.1 - 0.00029 20.6 12.0 0.00029 20.6 8.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.22 KEY71117.1 - 9.5e-69 227.1 0.3 2.5e-22 78.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein IU_nuc_hydro PF01156.14 KEY71118.1 - 5.3e-75 252.5 0.0 8.7e-75 251.8 0.0 1.3 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RED_N PF07808.8 KEY71119.1 - 1.8e-09 37.1 9.3 1.8e-09 37.1 6.5 2.3 2 0 0 2 2 2 1 RED-like protein N-terminal region IMS PF00817.15 KEY71120.1 - 1.7e-40 138.2 0.1 3.3e-40 137.2 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KEY71120.1 - 6.8e-19 68.0 0.0 1.5e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 KEY71120.1 - 2.3e-14 53.2 0.7 7.9e-07 28.9 0.0 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4414) HHH_5 PF14520.1 KEY71120.1 - 1.1e-05 25.4 0.1 3e-05 24.0 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain IMS_HHH PF11798.3 KEY71120.1 - 1.3e-05 24.9 0.1 0.00025 20.8 0.0 2.9 2 0 0 2 2 2 1 IMS family HHH motif BRCT PF00533.21 KEY71120.1 - 0.00019 21.4 0.0 0.00062 19.8 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain MgtE_N PF03448.12 KEY71120.1 - 0.025 14.8 1.3 13 6.1 0.0 3.9 4 0 0 4 4 4 0 MgtE intracellular N domain WSC PF01822.14 KEY71121.1 - 3.2e-17 62.2 9.1 4.1e-17 61.8 6.3 1.1 1 0 0 1 1 1 1 WSC domain SHR3_chaperone PF08229.6 KEY71122.1 - 1.3e-69 233.0 0.0 1.5e-69 232.9 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF2157 PF09925.4 KEY71122.1 - 0.1 12.2 0.5 1.3 8.5 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Mito_carr PF00153.22 KEY71123.1 - 1.5e-59 197.6 0.0 6.1e-20 70.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TspO_MBR PF03073.10 KEY71124.1 - 2.1e-38 131.1 7.9 2.9e-38 130.7 5.5 1.2 1 0 0 1 1 1 1 TspO/MBR family Pam17 PF08566.5 KEY71124.1 - 0.011 15.4 0.3 0.21 11.2 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Corona_NS3b PF03053.9 KEY71124.1 - 0.13 11.7 0.5 0.19 11.2 0.4 1.2 1 0 0 1 1 1 0 ORF3b coronavirus protein DUF2177 PF09945.4 KEY71124.1 - 0.79 9.7 6.7 5.6 6.9 0.0 3.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2177) AAA_22 PF13401.1 KEY71125.1 - 2.2e-13 50.4 0.0 5e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEY71125.1 - 6.3e-11 42.6 2.1 2.9e-10 40.4 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 KEY71125.1 - 1.6e-08 34.7 0.0 5.7e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KEY71125.1 - 0.0002 20.3 0.0 0.00068 18.5 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain Cdc6_C PF09079.6 KEY71125.1 - 0.0011 18.5 0.0 0.0043 16.7 0.0 1.9 2 0 0 2 2 1 1 CDC6, C terminal AAA_14 PF13173.1 KEY71125.1 - 0.0012 18.7 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEY71125.1 - 0.0079 15.9 0.1 0.074 12.8 0.0 2.7 3 0 0 3 3 2 1 Part of AAA domain AAA_30 PF13604.1 KEY71125.1 - 0.014 14.9 0.0 0.032 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KEY71125.1 - 0.016 15.0 0.0 0.051 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.1 KEY71125.1 - 0.018 13.7 0.0 0.045 12.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 KEY71125.1 - 0.019 13.6 0.0 0.029 13.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 KEY71125.1 - 0.019 14.6 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Miro PF08477.8 KEY71125.1 - 0.021 15.3 0.0 0.04 14.4 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_5 PF07728.9 KEY71125.1 - 0.045 13.4 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 KEY71125.1 - 0.049 12.6 0.0 0.092 11.7 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain AAA_11 PF13086.1 KEY71125.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 KEY71125.1 - 0.095 11.6 0.0 0.28 10.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 KEY71125.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 KEY71125.1 - 0.19 10.6 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Arrestin_N PF00339.24 KEY71126.1 - 5.3e-16 58.7 0.0 2e-13 50.4 0.0 3.3 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KEY71126.1 - 1.7e-05 24.9 0.0 0.00043 20.3 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain G-patch PF01585.18 KEY71127.1 - 8.4e-05 22.2 0.0 0.00059 19.5 0.0 2.5 1 1 0 1 1 1 1 G-patch domain CDC27 PF09507.5 KEY71127.1 - 0.0016 17.7 46.8 0.0023 17.2 32.4 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 MIP-T3 PF10243.4 KEY71127.1 - 0.46 8.8 54.6 0.65 8.4 37.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 AF-4 PF05110.8 KEY71127.1 - 6.5 4.4 41.6 9.1 3.9 28.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4187 PF13821.1 KEY71128.1 - 1.5e-24 85.3 0.0 4.3e-24 83.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) DUF3546 PF12066.3 KEY71128.1 - 2e-23 82.5 3.3 6e-23 80.9 2.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 KEY71128.1 - 6.2e-15 55.9 0.1 2e-14 54.2 0.1 1.8 1 0 0 1 1 1 1 Arsenite-resistance protein 2 Glyco_hydro_18 PF00704.23 KEY71129.1 - 4.1e-95 319.1 4.7 5.7e-95 318.6 3.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ADH_zinc_N PF00107.21 KEY71130.1 - 1e-33 115.6 1.0 1.5e-33 115.1 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY71130.1 - 6.5e-10 39.9 0.8 1.1e-09 39.2 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY71130.1 - 7.7e-06 25.6 0.0 3e-05 23.7 0.0 1.9 1 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KEY71130.1 - 0.0002 20.9 3.1 0.0037 16.8 1.0 2.2 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 KEY71130.1 - 0.0003 20.7 0.1 0.00056 19.8 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain DUF1254 PF06863.7 KEY71130.1 - 0.037 13.8 0.1 0.22 11.3 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1254) ubiquitin PF00240.18 KEY71131.1 - 3.7e-18 64.6 0.1 6.6e-18 63.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KEY71131.1 - 7.2e-09 35.2 4.2 3.6e-08 33.0 0.0 2.9 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 KEY71131.1 - 0.00083 18.9 0.2 0.0015 18.1 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 KEY71131.1 - 0.0021 17.9 0.1 0.0037 17.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KEY71131.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain NPR2 PF06218.6 KEY71132.1 - 1.5e-115 386.3 0.0 1.2e-96 324.0 0.0 2.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 tRNA-synt_1b PF00579.20 KEY71133.1 - 4.6e-71 239.3 0.0 5.9e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF4327 PF14217.1 KEY71133.1 - 0.038 13.7 3.1 1.1 9.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4327) CybS PF05328.7 KEY71134.1 - 3.8e-50 168.9 0.0 4.7e-50 168.6 0.0 1.1 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 KEY71134.1 - 0.21 11.4 1.5 1.1 9.0 0.7 1.9 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF3419 PF11899.3 KEY71135.1 - 5.9e-157 522.2 0.1 7.8e-157 521.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 KEY71135.1 - 3.7e-12 46.2 0.0 1e-09 38.3 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY71135.1 - 3.9e-09 37.0 0.0 1.2e-08 35.4 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY71135.1 - 8.3e-08 31.9 0.0 6.2e-07 29.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY71135.1 - 2e-07 30.4 0.1 0.00015 20.9 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KEY71135.1 - 2.4e-07 31.1 0.0 8.8e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY71135.1 - 5.3e-07 29.6 0.0 0.00032 20.6 0.0 3.8 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY71135.1 - 8.6e-06 26.1 0.0 0.00085 19.7 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY71135.1 - 1.5e-05 25.2 0.0 4.7e-05 23.6 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.14 KEY71135.1 - 0.00014 21.4 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 KEY71135.1 - 0.00085 18.4 0.0 0.004 16.2 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_32 PF13679.1 KEY71135.1 - 0.0088 15.7 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 KEY71135.1 - 0.06 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase AAA_16 PF13191.1 KEY71135.1 - 0.091 12.7 0.0 0.22 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Ada3 PF10198.4 KEY71136.1 - 3.6e-43 146.4 0.0 3.6e-43 146.4 0.0 2.4 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 Urease_alpha PF00449.15 KEY71137.1 - 6.8e-53 177.9 1.6 6.8e-53 177.9 1.1 1.8 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Amidohydro_1 PF01979.15 KEY71137.1 - 1.2e-51 176.3 0.5 1.9e-51 175.6 0.3 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_beta PF00699.15 KEY71137.1 - 2.6e-41 139.4 0.9 4.5e-41 138.7 0.1 1.8 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 KEY71137.1 - 3.4e-35 120.0 0.3 3e-21 75.3 0.0 2.6 2 0 0 2 2 2 2 Urease, gamma subunit Amidohydro_5 PF13594.1 KEY71137.1 - 1.1e-06 28.3 3.8 3.2e-06 26.8 2.6 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KEY71137.1 - 0.00094 18.4 0.1 0.0062 15.7 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_2 PF04909.9 KEY71137.1 - 0.0025 17.4 0.0 0.016 14.8 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase HMG_box PF00505.14 KEY71138.1 - 4.6e-07 30.0 0.7 4.6e-07 30.0 0.5 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KEY71138.1 - 0.0023 18.2 0.2 0.0023 18.2 0.1 2.7 3 0 0 3 3 3 1 HMG-box domain Het-C PF07217.6 KEY71139.1 - 5.6e-243 807.5 0.0 7.1e-243 807.2 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C zf-RING_2 PF13639.1 KEY71140.1 - 6.2e-11 41.9 9.9 1.2e-10 41.0 6.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEY71140.1 - 3.3e-05 23.8 10.4 6.9e-05 22.7 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEY71140.1 - 3.7e-05 23.2 9.6 6.6e-05 22.4 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEY71140.1 - 6.4e-05 22.9 4.8 0.00015 21.7 3.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KEY71140.1 - 7.8e-05 22.3 9.5 0.00013 21.5 6.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Vps39_2 PF10367.4 KEY71140.1 - 0.018 15.2 0.3 0.018 15.2 0.2 1.8 2 0 0 2 2 1 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_3 PF13920.1 KEY71140.1 - 0.025 14.2 12.3 0.05 13.2 8.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1049 PF06305.6 KEY71140.1 - 0.084 12.3 0.2 0.084 12.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Baculo_RING PF05883.6 KEY71140.1 - 0.11 12.3 1.3 0.78 9.5 0.6 2.1 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-C3HC4_4 PF15227.1 KEY71140.1 - 0.12 12.2 12.6 0.22 11.4 8.7 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 KEY71140.1 - 0.3 10.9 5.6 0.56 10.0 3.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pex2_Pex12 PF04757.9 KEY71142.1 - 3.3e-43 147.7 2.3 4.2e-43 147.4 1.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 KEY71142.1 - 0.0033 17.2 4.5 0.0074 16.1 3.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KEY71142.1 - 0.0038 17.2 5.5 0.0043 17.0 1.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KEY71142.1 - 0.071 12.8 1.1 0.32 10.7 0.7 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.1 KEY71142.1 - 1.7 8.5 7.5 23 4.9 2.4 2.6 2 1 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.1 KEY71142.1 - 1.8 8.2 8.1 13 5.4 3.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MFS_1_like PF12832.2 KEY71143.1 - 4.6e-16 58.3 0.2 4.6e-16 58.3 0.1 3.5 5 0 0 5 5 5 1 MFS_1 like family Pribosyltran PF00156.22 KEY71144.1 - 1e-17 64.0 0.0 1.7e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KEY71144.1 - 0.0059 15.8 0.0 0.0089 15.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Glyco_hydro_47 PF01532.15 KEY71145.1 - 1e-131 439.7 0.0 1.2e-131 439.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pkinase_C PF00433.19 KEY71145.1 - 0.033 14.7 0.2 0.095 13.2 0.1 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain Fungal_trans PF04082.13 KEY71147.1 - 7.6e-11 41.3 0.1 2e-10 39.9 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY71147.1 - 2.7e-06 27.1 10.0 2.7e-06 27.1 6.9 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-Tim10_DDP PF02953.10 KEY71148.1 - 1.9e-21 75.0 3.1 2.4e-21 74.7 2.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KEY71148.1 - 0.033 13.6 3.5 0.038 13.4 2.4 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) PG_binding_1 PF01471.13 KEY71149.1 - 0.00037 20.4 0.1 1.2 9.1 0.0 3.0 3 0 0 3 3 3 2 Putative peptidoglycan binding domain AAA_13 PF13166.1 KEY71149.1 - 0.008 14.6 3.3 0.013 14.0 2.3 1.2 1 0 0 1 1 1 1 AAA domain K-box PF01486.12 KEY71149.1 - 0.023 14.4 0.6 0.056 13.2 0.4 1.7 1 0 0 1 1 1 0 K-box region Sec2p PF06428.6 KEY71149.1 - 0.088 12.6 3.0 0.26 11.1 2.1 1.8 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p APG6 PF04111.7 KEY71149.1 - 0.46 9.4 3.5 0.88 8.5 2.4 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 CLTH PF10607.4 KEY71150.1 - 5.3e-31 107.2 0.0 3.3e-30 104.6 0.0 2.0 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KEY71150.1 - 1.1e-17 63.3 1.3 2.9e-17 62.1 0.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 KEY71150.1 - 8.7e-05 21.8 0.0 0.00015 21.0 0.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_2 PF13923.1 KEY71150.1 - 0.0021 18.0 0.3 0.0042 17.0 0.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEY71150.1 - 0.0026 17.5 0.4 0.0045 16.7 0.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KEY71150.1 - 0.0039 16.8 0.4 0.0066 16.1 0.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KEY71150.1 - 0.017 14.7 1.0 0.031 13.9 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEY71150.1 - 0.11 12.1 0.3 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ABC_tran PF00005.22 KEY71151.1 - 1.1e-37 129.4 0.0 2.7e-24 86.0 0.0 3.2 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEY71151.1 - 9.6e-28 97.3 21.0 3.8e-15 56.0 8.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_16 PF13191.1 KEY71151.1 - 4.7e-06 26.7 0.1 0.11 12.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KEY71151.1 - 7.5e-06 25.5 0.4 0.0015 18.0 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_21 PF13304.1 KEY71151.1 - 1.2e-05 25.5 0.2 2.8 7.8 0.0 4.1 4 0 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.18 KEY71151.1 - 1.6e-05 24.8 0.3 0.0045 16.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KEY71151.1 - 5.3e-05 22.4 0.2 0.008 15.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KEY71151.1 - 5.5e-05 22.6 0.6 0.012 15.0 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 KEY71151.1 - 6.4e-05 22.6 0.0 0.35 10.5 0.0 2.6 2 0 0 2 2 2 2 NACHT domain ArgK PF03308.11 KEY71151.1 - 8.9e-05 21.3 0.2 0.014 14.1 0.1 2.3 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 KEY71151.1 - 0.0001 22.7 0.7 0.14 12.6 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 KEY71151.1 - 0.00014 22.7 0.0 0.36 11.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KEY71151.1 - 0.00015 21.2 0.0 0.0058 16.1 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 KEY71151.1 - 0.00036 20.8 0.1 0.95 9.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 KEY71151.1 - 0.0004 20.2 1.3 0.046 13.5 0.1 2.6 3 0 0 3 3 2 1 Dynamin family AAA_23 PF13476.1 KEY71151.1 - 0.00042 20.7 0.0 0.85 9.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KEY71151.1 - 0.00055 19.3 0.4 0.67 9.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 KEY71151.1 - 0.00066 19.5 0.1 0.00066 19.5 0.0 1.7 2 0 0 2 2 1 1 Domain of unknown function DUF87 AAA_33 PF13671.1 KEY71151.1 - 0.00071 19.4 0.3 0.52 10.1 0.1 2.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KEY71151.1 - 0.00076 19.0 0.5 0.58 9.6 0.1 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 KEY71151.1 - 0.0012 18.0 0.2 0.44 9.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 KEY71151.1 - 0.0016 18.6 0.6 0.63 10.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KEY71151.1 - 0.003 17.0 2.3 1.4 8.3 0.2 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 KEY71151.1 - 0.0045 16.5 1.2 0.94 9.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 KEY71151.1 - 0.0058 15.3 1.1 0.15 10.6 0.1 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 KEY71151.1 - 0.0085 15.8 0.4 1.1 8.8 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KEY71151.1 - 0.014 15.3 1.6 1.3 8.9 0.2 2.5 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KEY71151.1 - 0.029 13.2 0.1 1.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein UPF0079 PF02367.12 KEY71151.1 - 0.035 13.7 0.3 1.7 8.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 KEY71151.1 - 0.041 12.7 0.4 4.9 5.9 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain KAP_NTPase PF07693.9 KEY71151.1 - 0.055 12.4 0.0 0.45 9.4 0.0 2.0 2 0 0 2 2 2 0 KAP family P-loop domain AAA PF00004.24 KEY71151.1 - 0.07 13.3 0.3 2.6 8.2 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KEY71151.1 - 0.079 12.5 0.5 13 5.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain SieB PF14163.1 KEY71151.1 - 0.084 12.4 0.1 0.22 11.1 0.1 1.7 1 0 0 1 1 1 0 Superinfection exclusion protein B RNA_helicase PF00910.17 KEY71151.1 - 0.09 12.9 0.1 7.2 6.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ATP-synt_ab PF00006.20 KEY71151.1 - 0.13 11.7 0.0 4.2 6.8 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SMC_N PF02463.14 KEY71151.1 - 0.17 11.0 0.0 23 4.1 0.0 3.2 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AIG1 PF04548.11 KEY71151.1 - 0.19 10.7 0.1 0.39 9.8 0.1 1.5 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.13 KEY71151.1 - 0.34 10.1 1.1 10 5.4 0.0 2.5 3 0 0 3 3 2 0 Ferrous iron transport protein B AAA_19 PF13245.1 KEY71151.1 - 0.39 10.4 8.2 2.5 7.9 0.2 4.1 4 0 0 4 4 3 0 Part of AAA domain ATP_bind_1 PF03029.12 KEY71151.1 - 0.51 9.8 2.9 11 5.4 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF3149 PF11346.3 KEY71151.1 - 0.67 9.5 4.4 0.92 9.1 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3149) DUF1129 PF06570.6 KEY71152.1 - 0.45 9.7 4.1 1.1 8.4 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Amidase PF01425.16 KEY71153.1 - 1.3e-57 195.6 0.1 1.5e-57 195.4 0.1 1.1 1 0 0 1 1 1 1 Amidase PBP1_TM PF14812.1 KEY71154.1 - 3.4 8.0 8.6 0.78 10.0 2.7 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PAS_3 PF08447.6 KEY71155.1 - 2.3e-12 46.8 0.0 4.7e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 KEY71155.1 - 5.8e-09 36.2 0.0 1.5e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 KEY71155.1 - 1e-06 28.4 0.0 2.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 KEY71155.1 - 0.00035 20.5 0.0 0.00071 19.5 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 KEY71155.1 - 0.00094 19.1 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold APC2 PF08672.6 KEY71155.1 - 0.086 13.1 0.0 26 5.1 0.0 2.5 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 SbcCD_C PF13558.1 KEY71156.1 - 5e-11 42.3 0.0 2.1e-10 40.3 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 KEY71156.1 - 6.4e-10 39.4 3.9 3.8e-05 23.7 0.1 3.7 4 1 0 4 4 4 2 AAA domain AAA_23 PF13476.1 KEY71156.1 - 7.6e-09 36.1 122.1 1.1e-07 32.4 46.2 7.9 2 2 2 4 4 1 1 AAA domain SMC_N PF02463.14 KEY71156.1 - 4e-07 29.4 0.0 4e-07 29.4 0.0 3.1 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 KEY71156.1 - 4.4e-07 28.7 117.9 0.0039 15.7 0.0 6.8 2 1 2 6 6 6 4 AAA domain AAA_15 PF13175.1 KEY71156.1 - 6.2e-06 25.5 0.0 6.2e-06 25.5 0.0 5.6 3 2 1 4 4 4 2 AAA ATPase domain AAA_29 PF13555.1 KEY71156.1 - 0.0029 17.0 0.0 0.0063 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Striatin PF08232.7 KEY71156.1 - 0.0049 17.1 11.8 0.0049 17.1 8.2 8.9 3 3 3 7 7 6 1 Striatin family Exonuc_VII_S PF02609.11 KEY71156.1 - 0.0074 16.0 0.7 0.0074 16.0 0.5 4.7 3 0 0 3 3 3 1 Exonuclease VII small subunit AAA_19 PF13245.1 KEY71156.1 - 0.039 13.7 0.0 0.25 11.1 0.0 2.5 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 KEY71156.1 - 0.071 13.4 0.0 0.071 13.4 0.0 7.9 2 1 1 3 3 1 0 ABC transporter Surfac_D-trimer PF09006.6 KEY71156.1 - 1.4 8.7 9.9 23 4.8 0.0 5.3 5 0 0 5 5 5 0 Lung surfactant protein D coiled-coil trimerisation PPP4R2 PF09184.6 KEY71157.1 - 4e-09 36.4 2.4 4.8e-09 36.1 0.0 2.2 3 0 0 3 3 3 1 PPP4R2 SPRY PF00622.23 KEY71157.1 - 1.4e-05 25.1 0.0 2.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 SPRY domain DUF935 PF06074.7 KEY71157.1 - 0.13 10.9 2.2 0.32 9.6 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Na_Ca_ex PF01699.19 KEY71158.1 - 4.3e-37 126.8 35.6 7.7e-22 77.4 10.5 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Pkinase PF00069.20 KEY71159.1 - 7.1e-65 218.7 0.0 1.3e-64 217.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY71159.1 - 2.1e-35 122.0 0.0 1.8e-30 105.9 0.0 2.1 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEY71159.1 - 0.00013 21.0 0.0 0.079 11.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KEY71159.1 - 0.0006 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KEY71159.1 - 0.042 12.9 0.0 0.075 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KEY71159.1 - 0.084 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family GWT1 PF06423.7 KEY71160.1 - 4.8e-42 143.2 2.3 4.8e-42 143.2 1.6 2.1 2 0 0 2 2 2 1 GWT1 Peroxin-13_N PF04088.8 KEY71160.1 - 0.12 12.3 0.7 5.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Peptidase_S8 PF00082.17 KEY71162.1 - 3.4e-45 154.3 0.0 5.9e-45 153.5 0.0 1.4 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 KEY71162.1 - 6.1e-10 39.5 0.0 1.1e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 KEY71162.1 - 0.036 13.7 0.0 0.5 10.0 0.0 2.5 2 0 0 2 2 2 0 PA domain Fungal_trans_2 PF11951.3 KEY71163.1 - 1.2e-46 159.0 0.2 1.5e-46 158.7 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KEY71164.1 - 5.3e-13 48.4 0.0 1e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF373 PF04123.8 KEY71165.1 - 0.09 11.7 2.4 0.12 11.4 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) AA_permease PF00324.16 KEY71165.1 - 0.12 10.7 7.0 0.17 10.2 4.9 1.1 1 0 0 1 1 1 0 Amino acid permease 7TMR-DISM_7TM PF07695.6 KEY71165.1 - 0.21 11.2 13.2 1 9.0 9.1 2.2 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF973 PF06157.6 KEY71165.1 - 1.5 7.7 5.5 1.3 7.8 3.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF973) DUF161 PF02588.10 KEY71165.1 - 2.5 8.4 8.6 38 4.6 1.5 2.5 1 1 1 2 2 2 0 Uncharacterized BCR, YitT family COG1284 YwiC PF14256.1 KEY71165.1 - 4.6 7.3 10.6 2.2 8.3 3.8 2.3 2 0 0 2 2 2 0 YwiC-like protein ParA PF10609.4 KEY71167.1 - 4.3e-37 125.8 0.0 7.5e-37 125.0 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KEY71167.1 - 2.1e-16 59.9 0.0 3.3e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 KEY71167.1 - 4.9e-07 29.0 0.0 5.3e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 KEY71167.1 - 6.7e-06 25.3 0.6 6.6e-05 22.0 0.3 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 KEY71167.1 - 2e-05 24.5 0.1 0.00013 21.8 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_26 PF13500.1 KEY71167.1 - 0.00044 19.9 0.2 0.05 13.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain YhjQ PF06564.7 KEY71167.1 - 0.0011 18.4 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 YhjQ protein AAA_25 PF13481.1 KEY71167.1 - 0.0012 18.2 0.2 0.0029 17.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 KEY71167.1 - 0.0016 17.2 0.5 0.003 16.3 0.3 1.4 1 0 0 1 1 1 1 ArgK protein Zeta_toxin PF06414.7 KEY71167.1 - 0.017 14.2 0.1 0.45 9.5 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin DUF258 PF03193.11 KEY71167.1 - 0.035 13.2 0.7 0.066 12.4 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SRP54 PF00448.17 KEY71167.1 - 0.061 12.7 0.1 1 8.7 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain APS_kinase PF01583.15 KEY71167.1 - 0.089 12.4 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase MMR_HSR1 PF01926.18 KEY71167.1 - 0.11 12.5 0.6 0.58 10.1 0.4 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase SAM_decarbox PF01536.11 KEY71168.1 - 5.7e-86 288.1 0.0 1e-84 284.0 0.0 2.4 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase Ribosomal_L24e PF01246.15 KEY71169.1 - 1.3e-25 88.9 1.1 2.8e-25 87.9 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e KIAA1430 PF13879.1 KEY71169.1 - 0.02 15.3 0.6 0.041 14.2 0.4 1.7 1 0 0 1 1 1 0 KIAA1430 homologue Nop10p PF04135.7 KEY71170.1 - 1.1e-19 69.8 0.0 1.3e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family YkuD_2 PF13645.1 KEY71170.1 - 0.056 12.6 0.0 0.056 12.6 0.0 1.1 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain NOB1_Zn_bind PF08772.6 KEY71171.1 - 1.5e-31 107.9 2.0 2.5e-31 107.3 1.4 1.3 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 KEY71171.1 - 0.013 15.3 6.9 0.013 15.3 4.8 2.2 2 1 0 2 2 2 0 Drug resistance and apoptosis regulator zf-NADH-PPase PF09297.6 KEY71171.1 - 0.072 12.6 4.3 0.055 12.9 0.6 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Ferritin_2 PF13668.1 KEY71172.1 - 7.4e-17 61.5 0.0 1.3e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain Peptidase_M13 PF01431.16 KEY71172.1 - 0.017 14.2 0.0 5 6.2 0.0 2.3 2 0 0 2 2 2 0 Peptidase family M13 AA_permease_2 PF13520.1 KEY71173.1 - 1.2e-78 264.5 35.6 1.5e-78 264.2 24.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEY71173.1 - 4.4e-18 64.8 31.1 6e-18 64.4 21.6 1.2 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_31 PF01055.21 KEY71174.1 - 8e-87 291.8 0.0 9.7e-87 291.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KEY71174.1 - 1.6e-14 53.4 0.0 4.5e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like FAD_binding_9 PF08021.6 KEY71174.1 - 0.03 14.3 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Aa_trans PF01490.13 KEY71175.1 - 4e-50 170.4 26.9 4.6e-50 170.2 18.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ATG27 PF09451.5 KEY71175.1 - 0.73 9.0 1.6 1.2 8.2 1.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 MFS_1 PF07690.11 KEY71176.1 - 2.6e-37 128.3 43.8 9.1e-37 126.5 19.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DLH PF01738.13 KEY71177.1 - 7.2e-20 71.2 0.8 7.7e-18 64.5 0.5 2.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KEY71177.1 - 7.7e-05 22.4 0.0 0.00013 21.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY71177.1 - 0.00073 19.4 0.9 0.01 15.7 0.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KEY71177.1 - 0.074 12.7 0.0 8.2 6.0 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hyd_WA PF06462.7 KEY71177.1 - 0.076 12.6 0.2 0.16 11.6 0.2 1.6 1 0 0 1 1 1 0 Propeller DHDPS PF00701.17 KEY71178.1 - 6.8e-30 103.6 0.0 8.3e-30 103.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Aldo_ket_red PF00248.16 KEY71179.1 - 2.6e-57 193.8 0.0 3.1e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_zinc_N PF00107.21 KEY71180.1 - 8.8e-07 28.5 0.0 1.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TraB PF01963.12 KEY71180.1 - 0.18 11.1 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 TraB family Glyco_hydro_47 PF01532.15 KEY71181.1 - 1.2e-160 535.0 0.0 1.4e-160 534.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 KEY71181.1 - 0.082 11.1 0.0 2.7 6.1 0.0 2.4 2 1 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) adh_short PF00106.20 KEY71183.1 - 1.5e-23 83.5 0.1 2.5e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY71183.1 - 3.9e-14 52.7 0.0 5.4e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY71183.1 - 1.8e-08 34.4 0.0 1.7e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KEY71183.1 - 0.0021 18.1 0.0 0.0074 16.3 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEY71183.1 - 0.0028 16.3 0.2 0.0096 14.6 0.1 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KEY71183.1 - 0.013 14.9 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ATP-grasp_5 PF13549.1 KEY71183.1 - 0.014 14.5 0.1 0.064 12.4 0.0 1.8 1 1 1 2 2 2 0 ATP-grasp domain NmrA PF05368.8 KEY71183.1 - 0.048 12.9 0.1 0.073 12.3 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.10 KEY71183.1 - 0.1 11.5 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KEY71183.1 - 0.1 11.4 0.1 0.17 10.7 0.1 1.6 1 1 0 1 1 1 0 Male sterility protein Glyco_hydro_61 PF03443.9 KEY71184.1 - 3.2e-46 157.9 0.0 3.9e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NAD_binding_10 PF13460.1 KEY71185.1 - 5e-11 42.9 0.0 7e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding APH PF01636.18 KEY71187.1 - 1.4e-15 57.6 0.0 2e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEY71187.1 - 0.001 18.6 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 KEY71187.1 - 0.05 12.7 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Metallophos PF00149.23 KEY71187.1 - 0.055 12.8 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase RIO1 PF01163.17 KEY71187.1 - 0.077 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family NAD_binding_4 PF07993.7 KEY71188.1 - 8.4e-42 142.8 0.0 1.2e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KEY71188.1 - 1.1e-23 83.3 0.0 1.7e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KEY71188.1 - 4.7e-14 52.3 0.0 8e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEY71188.1 - 5.7e-06 25.2 0.0 9.4e-05 21.2 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 KEY71188.1 - 8.2e-05 22.7 0.0 0.00019 21.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Zn_clus PF00172.13 KEY71188.1 - 0.011 15.6 3.6 0.02 14.7 2.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KEY71188.1 - 0.014 15.3 0.8 0.083 12.8 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Aldo_ket_red PF00248.16 KEY71189.1 - 6.1e-46 156.5 0.0 2.4e-45 154.5 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family DUF1832 PF08870.6 KEY71189.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1832) Fungal_trans PF04082.13 KEY71190.1 - 2.2e-25 89.0 1.8 3.6e-25 88.3 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_transf_8 PF01501.15 KEY71190.1 - 2.2e-20 73.0 0.1 4.3e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 adh_short_C2 PF13561.1 KEY71191.1 - 2.2e-35 122.5 0.1 2.7e-35 122.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEY71191.1 - 3.1e-21 75.9 1.0 4.6e-21 75.4 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY71191.1 - 9.4e-08 31.9 0.6 1.4e-07 31.3 0.4 1.2 1 0 0 1 1 1 1 KR domain Dabb PF07876.7 KEY71192.1 - 1e-06 29.0 0.1 5.9e-06 26.6 0.1 2.0 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain Fungal_trans PF04082.13 KEY71193.1 - 4.3e-29 101.1 0.0 6.5e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY71193.1 - 7.2e-09 35.4 13.8 1.3e-08 34.5 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KEY71194.1 - 7e-37 126.9 40.3 8.7e-35 120.0 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY71194.1 - 7.1e-11 41.3 8.7 7.1e-11 41.3 6.0 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KEY71194.1 - 1.8e-06 26.4 2.9 2.6e-06 25.9 2.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Amino_oxidase PF01593.19 KEY71195.1 - 7.1e-36 124.2 0.3 8.3e-27 94.3 0.3 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KEY71195.1 - 2.6e-06 27.3 0.0 8.2e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KEY71195.1 - 0.004 16.2 0.2 0.0069 15.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KEY71195.1 - 0.015 15.3 0.0 0.039 14.0 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY71195.1 - 0.02 15.3 0.1 0.044 14.2 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PD-C2-AF1 PF09310.5 KEY71195.1 - 0.043 12.9 0.1 0.072 12.2 0.1 1.2 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 Lactamase_B PF00753.22 KEY71196.1 - 7.5e-10 38.7 0.1 4.9e-09 36.1 0.1 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KEY71196.1 - 6e-05 22.6 0.0 7.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Baculo_PEP_C PF04513.7 KEY71197.1 - 0.012 15.4 4.8 2 8.2 0.0 3.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glyco_hydro_43 PF04616.9 KEY71198.1 - 7.4e-70 235.2 3.2 9.4e-70 234.9 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 MARVEL PF01284.18 KEY71199.1 - 4.6e-07 29.7 11.6 8.9e-07 28.8 4.7 2.1 1 1 1 2 2 2 2 Membrane-associating domain DUF3742 PF12553.3 KEY71199.1 - 0.081 13.4 1.0 13 6.3 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) Pkinase PF00069.20 KEY71200.1 - 1e-21 77.2 0.0 3.1e-12 46.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEY71200.1 - 4.7e-05 22.5 0.0 0.22 10.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase RTA1 PF04479.8 KEY71202.1 - 7.6e-31 107.3 6.0 1e-30 106.9 4.2 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF3290 PF11694.3 KEY71202.1 - 0.038 13.7 0.1 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3290) DUF1097 PF06496.6 KEY71202.1 - 1.7 8.4 10.7 0.12 12.1 1.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1097) DUF423 PF04241.10 KEY71202.1 - 4.9 7.1 8.3 0.37 10.7 0.4 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF423) Claudin_2 PF13903.1 KEY71202.1 - 5.5 6.6 9.4 1.4 8.5 0.4 2.8 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Fungal_trans_2 PF11951.3 KEY71203.1 - 3.8e-10 38.9 0.1 5.9e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.20 KEY71204.1 - 0.0014 17.8 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KEY71204.1 - 0.023 14.4 1.4 0.059 13.0 0.4 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KEY71204.1 - 0.047 12.7 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADH_N PF08240.7 KEY71205.1 - 5.3e-28 96.9 4.6 1e-27 96.0 3.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY71205.1 - 2.4e-21 75.6 0.0 4.3e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY71205.1 - 6.6e-07 30.2 0.0 1.2e-06 29.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 KEY71205.1 - 0.076 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fungal_lectin PF07938.7 KEY71206.1 - 2.2e-09 37.0 1.4 2.2e-06 27.1 0.0 3.2 2 2 2 4 4 4 2 Fungal fucose-specific lectin Caldesmon PF02029.10 KEY71206.1 - 0.035 12.5 15.1 0.049 12.0 10.4 1.1 1 0 0 1 1 1 0 Caldesmon Ycf1 PF05758.7 KEY71206.1 - 0.075 10.7 0.1 0.09 10.4 0.0 1.1 1 0 0 1 1 1 0 Ycf1 NAD_binding_10 PF13460.1 KEY71207.1 - 0.0013 18.8 0.0 0.0022 18.0 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEY71207.1 - 0.033 12.8 0.0 0.048 12.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AcetylCoA_hydro PF02550.10 KEY71208.1 - 1.4e-48 165.2 0.0 2.1e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 KEY71208.1 - 1.2e-39 135.4 0.0 1.8e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain PALP PF00291.20 KEY71209.1 - 9.2e-30 103.9 0.0 1.1e-29 103.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.13 KEY71209.1 - 0.0043 16.0 0.0 0.0062 15.4 0.0 1.2 1 0 0 1 1 1 1 LytB protein LMSTEN PF07988.7 KEY71209.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 LMSTEN motif Fungal_trans PF04082.13 KEY71211.1 - 8.2e-09 34.7 0.1 2.1e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY71211.1 - 6e-06 26.0 6.2 1e-05 25.3 4.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FliJ PF02050.11 KEY71212.1 - 0.011 15.7 4.6 0.045 13.8 2.5 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein DUF4164 PF13747.1 KEY71212.1 - 0.016 15.3 1.1 0.033 14.3 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Fib_alpha PF08702.5 KEY71212.1 - 5 7.2 6.9 1.7 8.7 2.7 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HSP70 PF00012.15 KEY71213.1 - 2.7e-08 32.2 0.2 1.4e-07 29.8 0.1 2.0 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KEY71213.1 - 0.0023 16.5 0.1 0.0074 14.9 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein Peptidase_M20 PF01546.23 KEY71214.1 - 3.6e-21 75.5 0.1 4.8e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KEY71214.1 - 1.9e-17 62.9 0.0 3e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KEY71214.1 - 0.00011 21.9 0.0 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 DicB PF05358.6 KEY71214.1 - 0.043 13.2 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 DicB protein PA14_2 PF10528.4 KEY71215.1 - 6.6e-14 51.8 0.0 1.5e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 GLEYA domain MFS_1 PF07690.11 KEY71216.1 - 1.2e-29 103.1 29.9 1.2e-29 103.1 20.7 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Ala_racemase_N PF01168.15 KEY71216.1 - 7.1e-24 84.5 0.3 7.1e-24 84.5 0.2 1.5 2 0 0 2 2 2 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.1 KEY71216.1 - 4.9e-19 68.3 0.0 1.1e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain GTP_CH_N PF12471.3 KEY71216.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.6 2 0 0 2 2 2 0 GTP cyclohydrolase N terminal Abhydrolase_3 PF07859.8 KEY71217.1 - 6.7e-61 205.5 0.0 8.4e-61 205.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KEY71217.1 - 4e-09 35.7 0.4 1.2e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.16 KEY71217.1 - 4.9e-06 25.9 0.0 8e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEY71217.1 - 0.00077 19.2 0.0 0.00096 18.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KEY71217.1 - 0.042 12.4 0.0 0.063 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) adh_short PF00106.20 KEY71218.1 - 9e-21 74.5 1.0 4e-20 72.3 0.7 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY71218.1 - 8e-10 38.8 0.0 1.1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY71218.1 - 6.3e-08 32.4 0.2 1.4e-07 31.3 0.1 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KEY71218.1 - 0.014 15.3 0.1 0.028 14.4 0.1 1.5 1 1 0 1 1 1 0 NADH(P)-binding Saccharop_dh PF03435.13 KEY71218.1 - 0.13 11.1 0.1 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase EamA PF00892.15 KEY71219.1 - 6.5e-21 74.6 30.9 1.8e-11 44.1 6.7 2.3 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KEY71219.1 - 0.00012 22.2 25.0 0.0057 16.8 3.1 2.9 3 1 0 3 3 3 2 Multidrug resistance efflux transporter MNHE PF01899.11 KEY71219.1 - 0.18 11.4 4.3 1.7 8.2 0.1 3.2 2 1 2 4 4 4 0 Na+/H+ ion antiporter subunit Glyco_hydro_62 PF03664.8 KEY71220.1 - 2.3e-135 449.9 5.2 2.9e-135 449.6 3.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.13 KEY71220.1 - 8.7e-11 41.2 19.6 2.2e-10 39.9 13.6 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KEY71220.1 - 0.034 14.1 8.8 0.077 13.0 6.1 1.7 1 1 0 1 1 1 0 Toxin 7 Pectate_lyase PF03211.8 KEY71221.1 - 7e-66 221.7 1.6 8.1e-66 221.4 1.1 1.0 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KEY71221.1 - 0.011 15.5 5.6 0.035 13.8 3.7 1.9 1 1 0 1 1 1 0 Right handed beta helix region Acetyltransf_1 PF00583.19 KEY71223.1 - 6.3e-17 61.3 0.1 8.2e-09 35.3 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEY71223.1 - 1.7e-15 56.9 0.0 4.3e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEY71223.1 - 2.5e-12 46.7 0.2 7.7e-06 25.7 0.0 3.6 3 1 0 3 3 3 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEY71223.1 - 1.8e-09 37.2 0.4 0.00049 19.7 0.0 2.6 2 1 0 2 2 2 2 FR47-like protein Acetyltransf_10 PF13673.1 KEY71223.1 - 2.5e-09 37.2 0.1 0.00035 20.6 0.0 3.0 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KEY71223.1 - 2.5e-05 24.0 0.2 0.099 12.5 0.0 2.4 2 0 0 2 2 2 2 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.1 KEY71223.1 - 0.032 13.9 0.1 0.43 10.3 0.0 2.5 3 0 0 3 3 3 0 ESCO1/2 acetyl-transferase DUF3749 PF12568.3 KEY71223.1 - 0.05 13.1 0.0 3.7 7.1 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF3696 PF12476.3 KEY71224.1 - 0.025 14.5 0.4 0.051 13.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) DUF3135 PF11333.3 KEY71225.1 - 0.081 13.0 0.0 1 9.5 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3135) Abhydrolase_6 PF12697.2 KEY71226.1 - 1.2e-05 25.2 0.1 3.7e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY71226.1 - 2.5e-05 24.0 0.0 3.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KEY71226.1 - 3.7e-05 23.1 0.0 6.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KEY71226.1 - 9.6e-05 22.0 0.0 0.00035 20.2 0.0 1.8 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 KEY71226.1 - 0.0003 20.4 0.0 0.00052 19.6 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.7 KEY71226.1 - 0.0074 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) LCAT PF02450.10 KEY71226.1 - 0.16 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Zn_clus PF00172.13 KEY71227.1 - 1.6e-06 27.8 9.7 2.4e-06 27.3 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEY71227.1 - 0.0018 16.9 0.2 0.0029 16.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4519 PF15012.1 KEY71228.1 - 0.00044 20.1 1.4 0.00069 19.4 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4519) GAS PF13851.1 KEY71228.1 - 0.025 13.7 0.8 0.033 13.3 0.6 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF507 PF04368.8 KEY71228.1 - 0.056 13.0 1.5 0.076 12.6 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF507) YonK PF09642.5 KEY71228.1 - 0.1 12.3 0.0 0.65 9.7 0.0 1.9 1 1 1 2 2 2 0 YonK protein Glyco_hydro_61 PF03443.9 KEY71229.1 - 9.6e-59 198.8 0.0 1.2e-58 198.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SGL PF08450.7 KEY71230.1 - 2.3e-10 40.2 0.1 2.5e-08 33.6 0.1 2.5 2 0 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 KEY71230.1 - 0.015 15.3 0.0 0.094 12.7 0.0 2.3 2 1 0 2 2 2 0 Strictosidine synthase Pec_lyase_C PF00544.14 KEY71231.1 - 2.4e-40 138.1 1.3 5e-40 137.1 0.9 1.5 1 1 0 1 1 1 1 Pectate lyase DUF2668 PF10873.3 KEY71232.1 - 0.0017 18.4 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2668) SKG6 PF08693.5 KEY71232.1 - 0.0077 15.5 2.7 0.025 13.9 1.8 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TctA PF01970.11 KEY71232.1 - 0.028 12.8 2.4 0.67 8.3 0.0 2.3 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctA family Amnionless PF14828.1 KEY71232.1 - 0.094 11.1 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Amnionless Gram_pos_anchor PF00746.16 KEY71232.1 - 8.8 6.2 7.4 49 3.8 5.1 2.4 1 1 0 1 1 1 0 Gram positive anchor MFS_1 PF07690.11 KEY71233.1 - 8e-40 136.6 20.8 8e-40 136.6 14.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY71233.1 - 2.8e-12 45.9 21.7 4.9e-11 41.8 15.1 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter ESSS PF10183.4 KEY71233.1 - 0.0054 17.1 0.1 0.018 15.4 0.1 1.9 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Peroxidase_2 PF01328.12 KEY71234.1 - 2.9e-49 167.4 0.0 3.6e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Copper-fist PF00649.13 KEY71236.1 - 4.1e-14 51.4 1.0 7.1e-14 50.7 0.7 1.3 1 0 0 1 1 1 1 Copper fist DNA binding domain HET PF06985.6 KEY71237.1 - 5.5e-33 114.0 0.0 8.8e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_12 PF13424.1 KEY71238.1 - 5.8e-18 64.6 9.0 0.00012 21.9 0.1 5.6 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 KEY71238.1 - 6.2e-10 38.6 10.6 0.59 10.1 0.1 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 KEY71238.1 - 4.9e-05 22.9 1.2 0.79 9.4 0.0 3.7 4 1 0 4 4 4 2 TPR repeat TPR_16 PF13432.1 KEY71238.1 - 0.00016 22.2 8.4 0.016 15.8 0.1 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEY71238.1 - 0.00073 19.2 2.1 1.2 9.2 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEY71238.1 - 0.18 11.6 4.8 16 5.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEY71238.1 - 0.19 12.2 4.2 72 4.1 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 KEY71238.1 - 5 7.8 17.0 16 6.3 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEY71238.1 - 5.7 7.8 20.1 14 6.6 0.0 6.2 6 1 1 7 7 7 0 Tetratricopeptide repeat Bac_rhodopsin PF01036.13 KEY71239.1 - 1.5e-29 102.9 29.7 1.9e-29 102.5 20.6 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Oxidored_FMN PF00724.15 KEY71240.1 - 5.4e-68 229.4 0.0 1.1e-64 218.5 0.0 2.5 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family PhaC_N PF07167.8 KEY71240.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Peptidase_M14 PF00246.19 KEY71241.1 - 8.4e-15 55.1 0.0 1.7e-14 54.1 0.0 1.6 1 1 0 1 1 1 1 Zinc carboxypeptidase Peptidase_S8 PF00082.17 KEY71241.1 - 5.7e-08 32.2 0.1 9.3e-08 31.5 0.1 1.4 1 0 0 1 1 1 1 Subtilase family CDO_I PF05995.7 KEY71241.1 - 0.033 13.3 0.2 0.84 8.7 0.0 2.3 2 0 0 2 2 2 0 Cysteine dioxygenase type I Nup88 PF10168.4 KEY71241.1 - 0.14 9.9 0.0 0.23 9.2 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore component Syntaphilin PF15290.1 KEY71241.1 - 0.2 11.1 0.1 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Abhydrolase_3 PF07859.8 KEY71242.1 - 4.5e-26 91.7 0.0 7.8e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_M28 PF04389.12 KEY71242.1 - 9e-22 77.6 0.0 1.7e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 DUF2424 PF10340.4 KEY71242.1 - 5e-10 38.5 0.0 2.6e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_M20 PF01546.23 KEY71242.1 - 4.6e-09 36.0 0.0 8e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Abhydrolase_5 PF12695.2 KEY71242.1 - 0.00053 19.7 0.0 0.015 15.0 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family COesterase PF00135.23 KEY71242.1 - 0.051 12.2 0.1 0.24 10.0 0.1 2.1 2 1 0 2 2 2 0 Carboxylesterase family MFS_1 PF07690.11 KEY71243.1 - 1.5e-41 142.3 23.8 1.5e-41 142.3 16.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY71243.1 - 1.3e-14 53.6 5.4 1.3e-14 53.6 3.7 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 KEY71243.1 - 4.7e-06 24.9 0.9 0.025 12.6 0.2 2.4 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Gly_kinase PF02595.10 KEY71244.1 - 5e-100 334.8 7.4 5.7e-100 334.6 5.1 1.0 1 0 0 1 1 1 1 Glycerate kinase family PLA2_B PF01735.13 KEY71245.1 - 1.2e-188 627.2 0.7 1.4e-188 627.0 0.5 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain p450 PF00067.17 KEY71246.1 - 1.7e-56 191.7 0.0 2.1e-56 191.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FSH1 PF03959.8 KEY71247.1 - 2.7e-31 108.6 0.0 3.4e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KEY71247.1 - 1.8e-05 24.7 0.7 6e-05 23.0 0.5 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY71247.1 - 0.00028 20.6 0.0 0.0004 20.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KEY71247.1 - 0.0034 16.8 0.1 0.033 13.6 0.0 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase PE-PPE PF08237.6 KEY71247.1 - 0.014 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_3 PF07859.8 KEY71247.1 - 0.072 12.6 0.5 0.45 10.0 0.0 2.3 3 0 0 3 3 3 0 alpha/beta hydrolase fold DIOX_N PF14226.1 KEY71248.1 - 2.1e-26 92.7 0.0 3.5e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KEY71248.1 - 7.8e-20 71.0 0.0 1.6e-19 70.0 0.0 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Dabb PF07876.7 KEY71249.1 - 3.3e-17 62.6 0.0 3.8e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain NAD_binding_8 PF13450.1 KEY71250.1 - 2.5e-09 37.0 0.9 8.3e-09 35.3 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KEY71250.1 - 1.3e-06 27.8 1.7 2e-06 27.1 1.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEY71250.1 - 5.7e-06 25.4 1.2 9.5e-06 24.7 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KEY71250.1 - 0.00011 22.5 0.1 0.00039 20.7 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEY71250.1 - 0.00013 20.5 0.5 0.00021 19.9 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 KEY71250.1 - 0.00016 20.7 1.2 0.00031 19.7 0.8 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEY71250.1 - 0.00086 19.4 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEY71250.1 - 0.0021 17.9 0.7 0.0038 17.1 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.7 KEY71250.1 - 0.0032 16.8 0.2 0.0051 16.2 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain FAD_binding_3 PF01494.14 KEY71250.1 - 0.0093 15.0 0.7 0.014 14.4 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KEY71250.1 - 0.011 14.8 0.1 0.017 14.2 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.19 KEY71250.1 - 0.014 14.5 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Sarcoglycan_2 PF05510.8 KEY71250.1 - 0.03 12.6 0.0 0.042 12.1 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon GIDA PF01134.17 KEY71250.1 - 0.05 12.4 0.4 0.072 11.9 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.13 KEY71250.1 - 0.2 11.6 0.3 0.4 10.7 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain MFS_1 PF07690.11 KEY71251.1 - 7.8e-42 143.2 63.3 1e-40 139.5 41.0 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KEY71251.1 - 4.1e-22 78.1 11.2 6.1e-22 77.5 7.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KEY71251.1 - 1.2e-11 43.8 13.3 1.2e-11 43.8 9.2 3.4 3 0 0 3 3 3 3 Sugar (and other) transporter DUF390 PF04094.9 KEY71251.1 - 3.3 5.6 6.1 4.2 5.2 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Fungal_trans PF04082.13 KEY71252.1 - 1.5e-17 63.3 1.0 2.1e-17 62.8 0.2 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY71252.1 - 8.1e-10 38.4 8.8 1.5e-09 37.5 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 KEY71254.1 - 0.0062 16.4 0.1 0.014 15.3 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEY71254.1 - 0.027 13.7 0.2 0.05 12.8 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family p450 PF00067.17 KEY71255.1 - 2e-46 158.4 0.0 2.5e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PTR PF12789.2 KEY71255.1 - 0.046 13.5 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 Phage tail repeat like SIR2 PF02146.12 KEY71256.1 - 1.8e-30 106.0 0.3 1.2e-27 96.8 0.2 2.2 1 1 0 1 1 1 1 Sir2 family DUF3797 PF12677.2 KEY71256.1 - 0.16 11.6 0.9 0.34 10.5 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) Glyco_hydro_28 PF00295.12 KEY71257.1 - 2e-35 122.3 7.8 2.1e-33 115.6 3.3 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 Shisa PF13908.1 KEY71259.1 - 9.3e-08 32.4 0.0 1.1e-07 32.1 0.0 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.10 KEY71259.1 - 0.0045 16.5 5.3 0.0081 15.6 3.7 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SLAC1 PF03595.12 KEY71259.1 - 0.005 15.5 0.0 0.0057 15.3 0.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Hum_adeno_E3A PF05393.6 KEY71259.1 - 0.046 13.3 2.4 0.067 12.8 1.7 1.2 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein DUF456 PF04306.8 KEY71259.1 - 0.05 13.6 0.3 0.063 13.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Herpes_gE PF02480.11 KEY71259.1 - 0.056 11.7 0.1 0.071 11.3 0.1 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4448 PF14610.1 KEY71259.1 - 0.073 12.5 0.1 0.086 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.1 KEY71259.1 - 0.074 13.4 0.0 0.097 13.0 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain GRA6 PF05084.8 KEY71259.1 - 0.084 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Granule antigen protein (GRA6) DUF4131 PF13567.1 KEY71259.1 - 0.2 11.0 0.9 0.31 10.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Lamp PF01299.12 KEY71259.1 - 0.34 10.0 1.0 0.55 9.3 0.7 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) CCSMST1 PF15013.1 KEY71259.1 - 0.52 10.2 2.8 0.82 9.6 1.9 1.2 1 0 0 1 1 1 0 CCSMST1 family PhoD PF09423.5 KEY71260.1 - 1.2e-155 518.5 4.7 1.5e-155 518.1 3.2 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase Tub_2 PF04525.7 KEY71260.1 - 1.6e-25 89.5 0.0 3.1e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Tubby C 2 SSF PF00474.12 KEY71261.1 - 5.4e-24 84.5 29.2 8.5e-24 83.9 20.3 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Peptidase_S8 PF00082.17 KEY71262.1 - 4.4e-45 154.0 0.1 9.4e-45 152.9 0.1 1.5 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 KEY71262.1 - 6.2e-14 52.3 0.1 1e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 KEY71262.1 - 0.0027 17.3 0.0 0.0092 15.6 0.0 1.9 2 0 0 2 2 2 1 PA domain Peroxidase_2 PF01328.12 KEY71263.1 - 3.1e-30 104.9 0.1 5e-30 104.2 0.1 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Amino_oxidase PF01593.19 KEY71263.1 - 7.2e-09 35.2 0.0 1.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Dynamin_N PF00350.18 KEY71263.1 - 1.1e-05 25.2 0.0 2.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family AAA_29 PF13555.1 KEY71263.1 - 0.0079 15.6 0.0 0.026 14.0 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Fungal_trans_2 PF11951.3 KEY71264.1 - 4e-08 32.2 0.7 4e-08 32.2 0.5 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.8 KEY71265.1 - 2.8e-37 128.3 2.0 2.8e-37 128.3 1.4 1.3 2 0 0 2 2 2 1 RTA1 like protein PGG PF13962.1 KEY71265.1 - 0.011 15.3 0.6 0.011 15.3 0.4 2.3 3 0 0 3 3 3 0 Domain of unknown function DUF3040 PF11239.3 KEY71265.1 - 5.4 7.1 6.1 4 7.5 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) HET PF06985.6 KEY71266.1 - 1.3e-33 116.1 0.0 2.1e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Zn_clus PF00172.13 KEY71267.1 - 2e-10 40.3 8.3 5.2e-10 39.0 5.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_3 PF00933.16 KEY71268.1 - 4.9e-47 160.3 0.0 6.2e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY71268.1 - 2.3e-12 46.9 0.6 1.9e-10 40.6 0.0 2.2 1 1 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain TrkH PF02386.11 KEY71269.1 - 1.5e-107 359.2 7.9 3e-103 345.0 3.8 2.1 2 0 0 2 2 2 2 Cation transport protein SCIMP PF15050.1 KEY71269.1 - 0.032 14.1 0.1 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 SCIMP protein ABC2_membrane PF01061.19 KEY71271.1 - 4e-81 271.1 52.5 8.8e-43 145.9 17.2 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 KEY71271.1 - 2.5e-32 112.0 0.0 4.6e-15 56.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KEY71271.1 - 8.9e-30 102.3 7.9 4.6e-29 100.1 0.0 3.3 4 0 0 4 4 2 1 CDR ABC transporter ABC_trans_N PF14510.1 KEY71271.1 - 1.2e-15 57.2 0.0 2.8e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KEY71271.1 - 4.6e-07 29.4 0.0 0.00026 20.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEY71271.1 - 0.00019 20.9 2.1 0.027 13.9 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 KEY71271.1 - 0.00042 20.2 0.7 0.025 14.4 0.0 3.1 3 1 0 3 3 3 1 AAA domain DUF258 PF03193.11 KEY71271.1 - 0.00058 19.0 0.0 0.014 14.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 KEY71271.1 - 0.0019 18.1 0.0 0.79 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEY71271.1 - 0.003 17.5 0.1 1.2 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 KEY71271.1 - 0.0031 16.7 0.0 0.14 11.3 0.0 2.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KEY71271.1 - 0.0056 16.8 0.5 1.6 8.8 0.1 3.2 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 KEY71271.1 - 0.0094 15.4 2.7 0.043 13.2 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.2 KEY71271.1 - 0.0095 15.0 48.6 0.014 14.4 10.8 3.1 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_19 PF13245.1 KEY71271.1 - 0.012 15.3 2.8 3.3 7.5 0.1 2.8 2 0 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 KEY71271.1 - 0.014 15.6 0.2 0.47 10.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 KEY71271.1 - 0.023 15.1 0.0 14 6.2 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein NACHT PF05729.7 KEY71271.1 - 0.026 14.2 0.7 4.1 7.0 0.1 2.8 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.1 KEY71271.1 - 0.033 15.0 0.0 0.74 10.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain PDR_assoc PF08370.6 KEY71271.1 - 0.034 13.6 6.7 0.64 9.5 0.2 3.6 3 0 0 3 3 3 0 Plant PDR ABC transporter associated AAA_23 PF13476.1 KEY71271.1 - 0.076 13.3 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KEY71271.1 - 0.077 13.1 0.1 11 6.1 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KEY71271.1 - 0.17 10.7 0.3 5.6 5.7 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein MMR_HSR1 PF01926.18 KEY71271.1 - 0.19 11.7 0.1 23 5.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KEY71271.1 - 0.25 10.7 0.2 9.1 5.6 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family UPF0079 PF02367.12 KEY71271.1 - 0.27 10.8 1.8 0.48 10.0 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 KEY71271.1 - 0.37 10.7 1.1 0.62 10.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain PduV-EutP PF10662.4 KEY71271.1 - 0.71 9.3 1.2 2.1 7.8 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 KEY71271.1 - 2.9 7.6 3.2 1.7 8.4 0.5 1.8 2 0 0 2 2 1 0 Domain of unknown function DUF87 Fungal_trans PF04082.13 KEY71272.1 - 2.2e-13 49.6 0.2 4e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY71272.1 - 0.41 10.5 3.5 0.72 9.8 2.4 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 KEY71273.1 - 2e-51 174.5 0.0 2.3e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ATP_bind_4 PF01902.12 KEY71274.1 - 6.5e-22 77.9 0.0 9.8e-16 57.7 0.0 3.2 3 0 0 3 3 3 3 ATP-binding region Ribonuc_L-PSP PF01042.16 KEY71274.1 - 1.4e-11 44.2 0.0 3.6e-07 29.9 0.0 3.3 3 0 0 3 3 3 2 Endoribonuclease L-PSP zf-C2H2 PF00096.21 KEY71275.1 - 5.5e-13 48.4 13.7 4.5e-07 29.8 1.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY71275.1 - 2.8e-09 36.6 13.2 0.00011 22.2 3.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEY71275.1 - 2.7e-08 33.6 13.5 3.4e-06 27.0 4.4 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 KEY71275.1 - 1.8e-06 27.9 5.4 4e-05 23.6 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KEY71275.1 - 1.8e-05 24.7 6.9 0.00031 20.8 0.7 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KEY71275.1 - 0.014 15.2 9.9 0.018 14.9 0.6 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger Elf1 PF05129.8 KEY71275.1 - 2.4 7.8 5.7 6.5 6.5 0.7 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-BED PF02892.10 KEY71275.1 - 5.8 6.7 8.1 3.7 7.3 2.1 2.2 1 1 1 2 2 2 0 BED zinc finger zf-C2HC_2 PF13913.1 KEY71275.1 - 7.2 6.3 8.5 5.7 6.7 1.6 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Glyco_hydro_16 PF00722.16 KEY71277.1 - 2.8e-42 144.0 1.7 4.7e-42 143.3 1.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Topoisom_I_N PF02919.10 KEY71278.1 - 2e-94 314.9 4.7 2e-94 314.9 3.3 3.9 5 0 0 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KEY71278.1 - 9.5e-85 283.4 8.2 9.5e-85 283.4 5.7 2.3 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 KEY71278.1 - 5.6e-30 102.8 0.1 5.6e-30 102.8 0.1 2.1 2 0 0 2 2 2 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 KEY71278.1 - 0.075 12.1 0.1 0.16 11.0 0.1 1.5 1 0 0 1 1 1 0 RolB/RolC glucosidase family zf-ZPR1 PF03367.8 KEY71278.1 - 0.093 11.8 2.9 4 6.5 0.0 3.0 2 1 1 3 3 3 0 ZPR1 zinc-finger domain ATP-synt PF00231.14 KEY71279.1 - 3.1e-72 243.3 3.2 3.5e-72 243.1 2.2 1.0 1 0 0 1 1 1 1 ATP synthase DUF4127 PF13552.1 KEY71279.1 - 0.03 12.7 0.4 0.049 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) Ribosomal_S3_C PF00189.15 KEY71279.1 - 0.054 13.7 0.2 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S3, C-terminal domain Amino_oxidase PF01593.19 KEY71280.1 - 9.7e-87 291.8 0.2 2.1e-86 290.8 0.2 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 KEY71280.1 - 1.2e-08 34.9 0.0 2.5e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 KEY71280.1 - 1.7e-08 34.3 0.0 4.9e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box_2 PF09011.5 KEY71280.1 - 2.9e-06 27.5 5.3 6.4e-06 26.4 3.7 1.6 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 KEY71280.1 - 8.3e-05 22.7 3.2 8.3e-05 22.7 2.2 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box DAO PF01266.19 KEY71280.1 - 0.0029 16.5 0.2 0.011 14.6 0.0 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Sec1 PF00995.18 KEY71281.1 - 3.6e-135 451.7 0.0 4.1e-135 451.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Swi5 PF07061.6 KEY71281.1 - 0.04 13.7 0.8 0.1 12.3 0.1 2.0 1 1 1 2 2 2 0 Swi5 UQ_con PF00179.21 KEY71282.1 - 2e-25 88.8 0.0 2.3e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEY71282.1 - 2.4e-08 33.8 0.0 3.1e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KEY71282.1 - 2e-05 24.4 0.2 3.1e-05 23.8 0.1 1.6 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 KEY71282.1 - 0.0003 20.4 0.1 0.00043 19.9 0.1 1.2 1 0 0 1 1 1 1 UEV domain DUF1478 PF07349.6 KEY71283.1 - 0.033 13.5 0.0 0.033 13.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1478) Pkinase PF00069.20 KEY71284.1 - 6.9e-69 231.8 0.0 8.8e-69 231.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY71284.1 - 8.6e-33 113.5 0.0 1.5e-32 112.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY71284.1 - 8e-05 21.7 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KEY71284.1 - 0.0026 17.1 0.0 0.0055 16.0 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 KEY71284.1 - 0.015 14.4 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_39 PF14090.1 KEY71285.1 - 0.095 12.1 0.1 0.44 10.0 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain ABC_membrane PF00664.18 KEY71286.1 - 1.6e-75 254.0 38.6 7.1e-40 137.1 6.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KEY71286.1 - 3.4e-65 218.4 0.2 3.5e-33 114.8 0.0 3.3 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KEY71286.1 - 3.4e-12 46.0 10.7 0.00027 20.2 0.2 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEY71286.1 - 4.4e-12 46.5 0.2 0.01 15.8 0.0 4.2 2 2 1 3 3 3 3 AAA domain ABC_ATPase PF09818.4 KEY71286.1 - 1e-09 37.5 0.4 0.014 13.9 0.0 3.8 4 1 0 4 4 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 KEY71286.1 - 3.1e-09 37.0 1.3 9.5e-05 22.4 0.1 3.3 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 KEY71286.1 - 6.1e-08 32.0 0.0 0.0059 15.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEY71286.1 - 1.7e-07 31.4 2.1 0.059 13.5 0.0 4.1 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KEY71286.1 - 1.9e-07 31.9 0.3 0.0075 17.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KEY71286.1 - 2.5e-07 30.0 1.1 0.00035 20.0 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 KEY71286.1 - 2.3e-06 26.9 0.0 0.035 13.1 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 KEY71286.1 - 7.5e-05 22.2 0.8 0.52 9.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 KEY71286.1 - 8e-05 22.9 0.2 0.08 13.2 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KEY71286.1 - 8.5e-05 22.4 0.4 0.14 12.0 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.1 KEY71286.1 - 8.6e-05 22.1 5.3 0.17 11.4 0.0 3.8 4 1 0 4 4 3 2 AAA domain AAA PF00004.24 KEY71286.1 - 0.00026 21.1 3.9 12 6.1 0.1 5.3 5 0 0 5 5 5 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 KEY71286.1 - 0.00036 20.3 1.1 0.36 10.7 0.1 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF3987 PF13148.1 KEY71286.1 - 0.00049 18.7 0.2 0.0021 16.6 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_5 PF07728.9 KEY71286.1 - 0.00051 19.7 0.1 2.3 7.9 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KEY71286.1 - 0.00083 19.0 0.1 0.11 12.2 0.0 3.2 3 0 0 3 3 2 1 Part of AAA domain AAA_33 PF13671.1 KEY71286.1 - 0.0019 18.1 0.0 0.15 11.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 KEY71286.1 - 0.0024 17.3 0.0 0.53 9.7 0.0 2.7 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.1 KEY71286.1 - 0.0047 16.9 0.0 2.4 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KEY71286.1 - 0.0048 16.3 0.2 0.11 11.9 0.0 3.0 3 0 0 3 3 3 1 AAA-like domain PRK PF00485.13 KEY71286.1 - 0.0096 15.4 0.0 5.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.9 KEY71286.1 - 0.025 14.2 0.1 1.1 8.9 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 KEY71286.1 - 0.031 14.7 0.1 12 6.4 0.0 3.0 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 KEY71286.1 - 0.038 14.3 13.2 1.6 9.0 5.5 3.1 2 1 1 3 3 2 0 AAA domain SRP54 PF00448.17 KEY71286.1 - 0.042 13.2 0.0 19 4.6 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain NB-ARC PF00931.17 KEY71286.1 - 0.054 12.3 0.1 3 6.5 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.18 KEY71286.1 - 0.12 12.3 0.1 19 5.2 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase Abhydrolase_6 PF12697.2 KEY71287.1 - 3.4e-22 79.4 2.8 3.4e-22 79.4 1.9 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY71287.1 - 1.7e-12 47.3 0.1 8.7e-12 45.0 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY71287.1 - 6.3e-07 29.1 0.5 1.2e-06 28.3 0.3 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KEY71287.1 - 8.4e-07 28.7 0.0 1.9e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 KEY71287.1 - 0.0065 15.7 0.1 0.068 12.4 0.1 2.5 1 1 0 1 1 1 1 Dienelactone hydrolase family UPF0227 PF05728.7 KEY71287.1 - 0.049 13.3 0.0 4.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) AIRC PF00731.15 KEY71288.1 - 1.5e-60 202.8 0.8 3.1e-60 201.8 0.5 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 KEY71288.1 - 1.9e-48 164.0 0.0 3.4e-48 163.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KEY71288.1 - 7.5e-14 51.8 0.1 1.6e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KEY71288.1 - 2.1e-08 33.7 0.0 5.5e-08 32.4 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 KEY71288.1 - 8.7e-07 28.4 0.0 1.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 KEY71288.1 - 3e-05 22.9 0.0 0.00032 19.5 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon 2-Hacid_dh_C PF02826.14 KEY71288.1 - 0.017 14.2 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FYVE PF01363.16 KEY71289.1 - 1.7e-21 75.8 0.3 1.7e-21 75.8 0.2 3.1 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 KEY71289.1 - 8.5e-08 31.9 5.8 8.5e-08 31.9 4.1 3.8 3 0 0 3 3 3 2 Ring finger domain zf-rbx1 PF12678.2 KEY71289.1 - 0.011 15.8 4.0 0.011 15.8 2.7 3.5 3 0 0 3 3 3 0 RING-H2 zinc finger FYVE_2 PF02318.11 KEY71289.1 - 0.013 15.4 2.0 0.013 15.4 1.4 2.7 3 0 0 3 3 3 0 FYVE-type zinc finger Rad50_zn_hook PF04423.9 KEY71289.1 - 0.15 11.5 0.2 0.15 11.5 0.1 2.5 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C3HC4_2 PF13923.1 KEY71289.1 - 0.43 10.6 34.5 0.024 14.6 4.2 3.8 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-piccolo PF05715.8 KEY71289.1 - 0.68 9.9 8.1 0.94 9.5 2.6 2.7 2 0 0 2 2 2 0 Piccolo Zn-finger C2 PF00168.25 KEY71290.1 - 2.6e-70 232.2 3.3 3.2e-20 71.7 0.0 5.5 5 0 0 5 5 5 5 C2 domain DUF2404 PF10296.4 KEY71290.1 - 0.04 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) DUF4429 PF14472.1 KEY71290.1 - 0.071 13.4 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4429) Proteasome PF00227.21 KEY71291.1 - 7.7e-48 162.2 0.2 9.3e-48 162.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF554 PF04474.7 KEY71291.1 - 0.0048 16.0 0.1 0.0065 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF554) DUF3222 PF11519.3 KEY71291.1 - 0.02 14.8 0.6 6.3 6.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3222) Aminotran_1_2 PF00155.16 KEY71292.1 - 2.1e-30 105.8 0.0 3.2e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KEY71292.1 - 0.0014 16.9 0.0 0.0031 15.8 0.0 1.5 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme BATS PF06968.8 KEY71293.1 - 7.5e-07 28.9 0.0 2.1e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Abhydrolase_2 PF02230.11 KEY71294.1 - 6.9e-20 71.4 0.0 5.4e-16 58.7 0.0 3.0 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase adh_short PF00106.20 KEY71295.1 - 3.1e-25 89.0 0.0 6.1e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY71295.1 - 4.5e-14 52.8 0.0 9.8e-14 51.6 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY71295.1 - 3.1e-10 40.0 0.1 6.6e-10 38.9 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KEY71295.1 - 9.2e-06 25.2 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KEY71295.1 - 0.00019 20.6 0.0 0.00026 20.2 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KEY71295.1 - 0.00048 20.1 0.0 0.007 16.3 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KEY71295.1 - 0.0043 15.9 0.0 0.011 14.6 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain DUF3425 PF11905.3 KEY71296.1 - 3.1e-25 88.6 0.2 6.5e-25 87.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_2 PF07716.10 KEY71296.1 - 0.0035 17.1 6.2 0.0035 17.1 4.3 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 KEY71296.1 - 0.026 14.4 7.2 0.047 13.6 5.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor adh_short_C2 PF13561.1 KEY71298.1 - 3.2e-17 63.0 0.0 4.6e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEY71298.1 - 1.9e-15 57.1 0.0 6.5e-15 55.4 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY71298.1 - 0.00054 19.6 0.1 0.0008 19.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY71298.1 - 0.063 12.7 0.0 0.23 10.8 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.11 KEY71299.1 - 1.3e-22 80.0 46.8 5.4e-12 45.1 12.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Bac_rhamnosid PF05592.6 KEY71300.1 - 4.7e-171 569.4 0.0 6e-171 569.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 KEY71300.1 - 1.8e-45 154.5 0.1 3.4e-45 153.6 0.1 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain DUF1817 PF08847.6 KEY71301.1 - 0.11 12.0 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1817) Zn_clus PF00172.13 KEY71302.1 - 5.2e-08 32.6 8.1 1.6e-07 31.0 5.6 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KEY71303.1 - 2.1e-70 237.5 18.8 2.5e-70 237.3 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY71303.1 - 7e-19 67.7 31.8 5.9e-12 44.9 10.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily VitK2_biosynth PF02621.9 KEY71303.1 - 0.037 13.2 0.1 0.064 12.4 0.1 1.3 1 0 0 1 1 1 0 Menaquinone biosynthesis GMC_oxred_N PF00732.14 KEY71304.1 - 3.9e-26 91.9 0.0 7.7e-26 90.9 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY71304.1 - 3.3e-23 82.5 1.1 8.4e-23 81.2 0.8 1.8 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KEY71304.1 - 1e-06 27.8 1.1 8.1e-06 24.9 0.8 2.3 2 1 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KEY71304.1 - 7.3e-05 21.4 0.3 0.00036 19.1 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 KEY71304.1 - 0.0001 21.3 0.3 0.0062 15.4 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KEY71304.1 - 0.00097 18.2 0.1 0.002 17.2 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 KEY71304.1 - 0.0014 18.7 0.0 0.19 11.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY71304.1 - 0.0037 16.2 0.1 0.0061 15.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEY71304.1 - 0.0043 16.9 0.1 0.1 12.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY71304.1 - 0.0049 16.8 0.6 0.015 15.2 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 KEY71304.1 - 0.028 13.8 0.1 0.056 12.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Kinesin PF00225.18 KEY71305.1 - 1.1e-50 172.2 0.0 2.6e-28 98.7 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain DUF4094 PF13334.1 KEY71305.1 - 0.041 14.2 0.7 0.12 12.7 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Snapin_Pallidin PF14712.1 KEY71305.1 - 0.14 12.4 0.8 0.27 11.5 0.6 1.4 1 0 0 1 1 1 0 Snapin/Pallidin Laminin_II PF06009.7 KEY71305.1 - 0.32 10.7 3.5 3.3 7.4 2.3 2.2 1 1 0 1 1 1 0 Laminin Domain II HATPase_c PF02518.21 KEY71306.1 - 3.9e-19 68.3 0.1 8.8e-19 67.2 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KEY71306.1 - 6.8e-17 61.4 0.1 1.5e-16 60.4 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KEY71306.1 - 3.1e-13 49.4 0.2 7.5e-13 48.2 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 KEY71306.1 - 0.00025 21.1 0.0 0.65 10.1 0.0 2.8 2 1 0 2 2 2 2 GAF domain GAF PF01590.21 KEY71306.1 - 0.003 17.6 0.0 0.16 12.0 0.0 2.8 2 0 0 2 2 2 1 GAF domain FAD_binding_8 PF08022.7 KEY71307.1 - 0.016 15.0 0.2 6.6 6.6 0.0 2.3 2 0 0 2 2 2 0 FAD-binding domain Glyco_hydro_11 PF00457.12 KEY71309.1 - 2.1e-44 151.0 5.8 2.4e-44 150.8 4.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CFEM PF05730.6 KEY71310.1 - 7.5e-08 32.0 6.8 1.2e-07 31.4 4.7 1.3 1 0 0 1 1 1 1 CFEM domain adh_short_C2 PF13561.1 KEY71311.1 - 9.7e-31 107.3 0.3 1.1e-30 107.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEY71311.1 - 3.9e-27 95.1 0.8 4.9e-27 94.8 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY71311.1 - 7e-14 51.8 0.3 9.6e-14 51.4 0.2 1.1 1 0 0 1 1 1 1 KR domain SurE PF01975.12 KEY71312.1 - 7.2e-40 136.4 0.0 1.1e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Sulfatase PF00884.18 KEY71313.1 - 3.9e-51 174.0 0.0 5e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KEY71313.1 - 0.019 14.3 0.4 0.11 11.8 0.3 1.9 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Methyltransf_23 PF13489.1 KEY71314.1 - 1.9e-20 73.2 0.0 3.5e-20 72.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY71314.1 - 5.2e-12 46.0 0.0 1.2e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY71314.1 - 4.7e-09 36.6 0.0 1.9e-08 34.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY71314.1 - 1.1e-08 35.6 0.0 3.1e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY71314.1 - 1.6e-07 31.0 0.0 0.00013 21.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.13 KEY71314.1 - 5.7e-06 25.6 0.0 1.5e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KEY71314.1 - 0.00075 19.5 0.0 0.0022 18.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY71314.1 - 0.0013 19.0 0.0 0.0063 16.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY71314.1 - 0.0017 17.7 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KEY71314.1 - 0.0026 16.9 0.0 0.0054 15.8 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 KEY71314.1 - 0.0044 16.4 0.0 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 KEY71314.1 - 0.0083 15.1 0.0 0.018 14.1 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 KEY71314.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.15 KEY71314.1 - 0.066 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase adh_short PF00106.20 KEY71315.1 - 1e-15 58.0 0.0 1.5e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY71315.1 - 1.9e-09 37.4 0.0 2.7e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY71315.1 - 0.0036 16.7 0.0 0.0049 16.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KEY71315.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 KEY71315.1 - 0.054 12.3 0.0 0.079 11.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3505 PF12013.3 KEY71316.1 - 3e-27 94.9 0.8 5.3e-27 94.2 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) Fungal_trans_2 PF11951.3 KEY71316.1 - 2.9e-06 26.1 0.4 4.7e-06 25.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KEY71317.1 - 5.5e-24 84.5 52.3 6.8e-15 54.6 16.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Asparaginase PF00710.15 KEY71318.1 - 3.2e-57 193.7 0.1 3.9e-57 193.5 0.1 1.1 1 0 0 1 1 1 1 Asparaginase Acyl_transf_3 PF01757.17 KEY71319.1 - 2.5e-27 95.6 25.3 4.1e-27 94.9 17.5 1.4 1 1 0 1 1 1 1 Acyltransferase family Peptidase_M35 PF02102.10 KEY71321.1 - 7.5e-78 261.6 13.3 9.8e-78 261.3 9.2 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 KEY71321.1 - 2.9e-08 34.3 1.2 5.9e-08 33.3 0.9 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase CARDB PF07705.6 KEY71321.1 - 0.041 13.9 0.2 0.16 12.0 0.1 1.9 1 1 0 1 1 1 0 CARDB Exo_endo_phos PF03372.18 KEY71322.1 - 3.6e-15 56.5 0.4 5.3e-15 56.0 0.3 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KEY71322.1 - 0.002 17.7 0.0 0.026 14.1 0.0 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase He_PIG PF05345.7 KEY71322.1 - 0.031 14.2 1.2 0.11 12.5 0.5 2.2 1 1 0 1 1 1 0 Putative Ig domain PA14 PF07691.7 KEY71322.1 - 0.11 12.1 0.2 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 PA14 domain FAD_binding_3 PF01494.14 KEY71323.1 - 1.1e-33 116.7 0.0 1.7e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KEY71323.1 - 5e-06 26.4 0.3 1.2e-05 25.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEY71323.1 - 7.3e-06 25.0 0.8 7.3e-06 25.0 0.6 1.5 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.19 KEY71323.1 - 4.3e-05 22.7 0.8 0.037 13.0 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.9 KEY71323.1 - 0.0001 20.8 0.1 0.00023 19.7 0.1 1.6 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 KEY71323.1 - 0.00012 21.3 0.0 0.00021 20.4 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 KEY71323.1 - 0.00015 20.7 1.2 0.00073 18.5 0.5 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEY71323.1 - 0.00015 20.7 0.3 0.25 10.2 0.2 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEY71323.1 - 0.00027 20.8 0.2 0.00076 19.4 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY71323.1 - 0.0016 18.5 0.0 0.004 17.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KEY71323.1 - 0.0039 16.7 0.3 0.0091 15.5 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KEY71323.1 - 0.0055 15.8 0.0 0.0097 15.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KEY71323.1 - 0.0056 17.0 0.3 0.016 15.5 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEY71323.1 - 0.032 13.0 0.1 0.067 12.0 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.11 KEY71323.1 - 0.053 12.9 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RTA1 PF04479.8 KEY71324.1 - 7.6e-57 192.3 9.6 9.3e-57 192.0 6.6 1.1 1 0 0 1 1 1 1 RTA1 like protein Kei1 PF08552.6 KEY71324.1 - 9.3e-05 22.1 0.6 0.00068 19.3 0.1 2.1 2 0 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 DUF2254 PF10011.4 KEY71324.1 - 0.035 12.5 0.3 0.06 11.8 0.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF1180 PF06679.7 KEY71324.1 - 0.045 13.6 0.2 5.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) HemY_N PF07219.8 KEY71324.1 - 0.11 12.0 0.8 27 4.3 0.0 3.1 2 1 0 2 2 2 0 HemY protein N-terminus Caveolin PF01146.12 KEY71324.1 - 0.14 11.7 0.0 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 Caveolin Zn_clus PF00172.13 KEY71325.1 - 7.9e-06 25.6 7.9 1.4e-05 24.9 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEY71325.1 - 0.00048 18.8 0.4 0.00077 18.1 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_43 PF04616.9 KEY71326.1 - 5.6e-59 199.5 4.8 6.7e-59 199.3 3.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 AbfB PF05270.8 KEY71326.1 - 1.8e-09 37.4 0.0 3.7e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) GMC_oxred_N PF00732.14 KEY71327.1 - 1.7e-42 145.5 0.0 2.4e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY71327.1 - 7.2e-25 87.9 0.0 1.3e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 KEY71327.1 - 0.016 15.3 0.1 0.53 10.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEY71327.1 - 0.036 13.1 0.1 0.071 12.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 KEY71327.1 - 0.053 12.4 3.3 0.28 10.0 0.6 2.7 1 1 0 3 3 3 0 FAD dependent oxidoreductase TrkA_N PF02254.13 KEY71327.1 - 0.055 13.4 0.2 0.19 11.7 0.2 1.9 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_8 PF13450.1 KEY71327.1 - 0.11 12.5 0.4 0.37 10.8 0.2 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GATA PF00320.22 KEY71328.1 - 5e-10 38.5 2.8 8.6e-10 37.7 1.9 1.4 1 0 0 1 1 1 1 GATA zinc finger PolC_DP2 PF03833.8 KEY71328.1 - 0.041 11.5 0.9 0.057 11.0 0.6 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Methyltransf_23 PF13489.1 KEY71329.1 - 3.8e-17 62.4 0.0 5.2e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY71329.1 - 1.1e-15 57.8 0.0 1.8e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY71329.1 - 1.7e-14 54.3 0.0 2.4e-12 47.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY71329.1 - 5.5e-13 48.7 0.0 6.5e-12 45.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY71329.1 - 1.4e-12 47.8 0.0 3.3e-12 46.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY71329.1 - 2.2e-05 24.7 0.0 5.1e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KEY71329.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KEY71329.1 - 0.0015 17.7 0.0 0.017 14.2 0.0 2.4 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KEY71329.1 - 0.0036 17.3 0.1 0.0092 16.0 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KEY71329.1 - 0.0083 15.1 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.6 KEY71329.1 - 0.048 12.3 0.0 0.15 10.7 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) NodS PF05401.6 KEY71329.1 - 0.12 11.7 0.0 1.6 8.0 0.0 2.0 2 0 0 2 2 2 0 Nodulation protein S (NodS) BCS1_N PF08740.6 KEY71330.1 - 9.7e-27 93.7 0.3 1.6e-26 93.1 0.2 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KEY71330.1 - 7.5e-24 84.4 0.0 1.3e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KEY71330.1 - 5.9e-05 22.2 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KEY71330.1 - 0.0012 19.6 0.0 0.0036 18.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KEY71330.1 - 0.012 15.7 0.0 0.041 14.0 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.1 KEY71330.1 - 0.013 15.4 0.5 0.051 13.5 0.3 2.2 1 1 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.8 KEY71330.1 - 0.013 14.3 0.0 0.025 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 KEY71330.1 - 0.015 15.0 0.0 0.074 12.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KEY71330.1 - 0.024 14.0 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Endonuc-dimeris PF09124.5 KEY71330.1 - 0.054 13.1 0.1 0.13 11.8 0.1 1.6 1 1 0 1 1 1 0 T4 recombination endonuclease VII, dimerisation AAA_22 PF13401.1 KEY71330.1 - 0.075 13.1 0.0 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KEY71330.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 KEY71330.1 - 0.15 10.7 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.1 KEY71330.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 KEY71331.1 - 2.3e-24 85.7 21.2 2.3e-24 85.7 14.7 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4066 PF13278.1 KEY71332.1 - 3e-28 98.1 0.0 4.2e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KEY71332.1 - 3.3e-14 52.5 0.0 5e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 KEY71332.1 - 0.0035 16.8 0.0 0.0046 16.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 KEY71332.1 - 0.15 11.6 0.0 0.35 10.4 0.0 1.5 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain Cyt-b5 PF00173.23 KEY71333.1 - 7.4e-17 60.9 0.2 2.5e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.19 KEY71333.1 - 3.5e-13 49.5 0.0 5.8e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KEY71333.1 - 9e-07 29.4 0.0 2.3e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain COesterase PF00135.23 KEY71334.1 - 1.7e-96 324.0 0.0 2.6e-96 323.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEY71334.1 - 0.00081 19.0 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1965 PF09248.5 KEY71334.1 - 0.0029 17.4 0.0 0.011 15.6 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Peptidase_S9 PF00326.16 KEY71334.1 - 0.07 12.3 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase_phd PF10503.4 KEY71335.1 - 5.2e-23 81.4 0.7 8.4e-23 80.7 0.5 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.13 KEY71335.1 - 1.6e-13 50.0 6.2 1.6e-13 50.0 4.3 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 KEY71335.1 - 6.4e-10 38.6 1.4 9.3e-10 38.0 1.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEY71335.1 - 1.3e-06 28.2 0.1 2.1e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY71335.1 - 0.00021 20.9 0.0 0.00032 20.3 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEY71335.1 - 0.00022 21.2 0.2 0.00026 20.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KEY71335.1 - 0.0075 15.8 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KEY71335.1 - 0.011 15.1 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF897 PF05982.7 KEY71335.1 - 0.016 14.0 5.5 0.74 8.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF897) BAAT_C PF08840.6 KEY71335.1 - 0.058 13.0 0.2 0.16 11.6 0.1 1.7 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal adh_short_C2 PF13561.1 KEY71336.1 - 3.8e-25 89.0 0.0 4.7e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEY71336.1 - 7.7e-25 87.7 0.1 9.6e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY71336.1 - 3.1e-08 33.4 0.0 4.8e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KEY71336.1 - 0.0088 15.8 0.1 0.026 14.2 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KEY71336.1 - 0.036 13.4 0.0 0.069 12.5 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family WVELL PF14043.1 KEY71336.1 - 0.12 12.0 0.0 0.36 10.4 0.0 1.8 1 0 0 1 1 1 0 WVELL protein 3HCDH_N PF02737.13 KEY71336.1 - 0.12 11.9 0.0 2.1 7.9 0.0 2.6 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KEY71336.1 - 0.14 11.5 0.2 0.43 9.9 0.1 1.8 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AP_endonuc_2 PF01261.19 KEY71337.1 - 3e-30 105.1 0.0 4.1e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Serine_rich PF08824.5 KEY71337.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Serine rich protein interaction domain Glyco_hydro_61 PF03443.9 KEY71338.1 - 5.3e-25 88.5 0.0 8.8e-25 87.8 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 adh_short PF00106.20 KEY71339.1 - 2.3e-17 63.3 10.5 4.4e-16 59.2 7.3 2.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY71339.1 - 1.5e-12 47.8 0.2 3.6e-12 46.5 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY71339.1 - 1.1e-08 34.9 7.9 5.2e-08 32.7 0.6 2.5 2 1 0 2 2 2 2 KR domain 3Beta_HSD PF01073.14 KEY71339.1 - 0.022 13.4 0.2 0.036 12.7 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KEY71339.1 - 0.029 14.3 1.2 0.18 11.8 0.3 2.0 2 0 0 2 2 2 0 NADH(P)-binding Shikimate_DH PF01488.15 KEY71339.1 - 0.038 14.0 0.1 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PAD_porph PF04371.10 KEY71339.1 - 0.041 12.9 0.0 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 Porphyromonas-type peptidyl-arginine deiminase UbiA PF01040.13 KEY71340.1 - 1.3e-22 80.2 17.6 1.7e-22 79.8 12.2 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3040 PF11239.3 KEY71340.1 - 0.092 12.8 6.6 1.5 8.9 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) DUF4131 PF13567.1 KEY71340.1 - 1.3 8.3 13.2 1.2 8.5 3.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) AMP-binding PF00501.23 KEY71341.1 - 2.9e-33 114.8 0.0 5.1e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KEY71341.1 - 9.3e-20 70.5 0.0 1.5e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KEY71341.1 - 1.1e-07 31.4 0.0 3.1e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KEY71341.1 - 2.5e-05 24.4 0.3 9.3e-05 22.6 0.2 2.1 1 1 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 KEY71341.1 - 0.023 14.6 3.4 0.069 13.0 0.1 3.0 2 1 0 2 2 2 0 short chain dehydrogenase GH3 PF03321.8 KEY71341.1 - 0.044 12.2 0.1 0.11 10.9 0.0 1.5 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Polysacc_synt_2 PF02719.10 KEY71341.1 - 0.23 10.2 0.0 4.7 6.0 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein ketoacyl-synt PF00109.21 KEY71342.1 - 7.5e-70 235.2 0.1 7.5e-70 235.2 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KEY71342.1 - 4.5e-31 107.1 0.0 4.5e-31 107.1 0.0 2.2 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KEY71342.1 - 3.8e-23 82.3 0.2 7.3e-22 78.1 0.0 2.4 2 0 0 2 2 2 1 Acyl transferase domain PP-binding PF00550.20 KEY71342.1 - 2.2e-19 69.4 6.0 1.3e-09 38.1 0.4 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_3 PF07859.8 KEY71342.1 - 4.8e-13 49.1 0.1 1.7e-12 47.3 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY71342.1 - 1.7e-07 31.1 1.4 1.8e-06 27.7 0.0 3.1 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 KEY71342.1 - 6.9e-06 25.2 0.0 1.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Peptidase_S9 PF00326.16 KEY71342.1 - 3.5e-05 23.1 0.0 0.095 11.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.15 KEY71342.1 - 0.0015 18.7 0.0 0.0035 17.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.11 KEY71342.1 - 0.14 11.6 0.0 3.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase COesterase PF00135.23 KEY71342.1 - 0.17 10.5 0.0 0.3 9.7 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family Zn_clus PF00172.13 KEY71343.1 - 6.7e-09 35.5 7.8 6.7e-09 35.5 5.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY71343.1 - 1.2e-07 30.8 0.3 2.1e-07 30.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DDE_Tnp_1_7 PF13843.1 KEY71344.1 - 1.2e-17 64.0 0.0 1.6e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 HET PF06985.6 KEY71345.1 - 0.0022 18.1 0.0 0.0029 17.7 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_10 PF13374.1 KEY71346.1 - 8.5e-09 35.0 0.0 0.0011 18.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEY71346.1 - 2.7e-07 30.3 0.0 8.9e-07 28.7 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat NB-ARC PF00931.17 KEY71346.1 - 4.2e-06 25.8 0.1 7.3e-05 21.7 0.1 2.1 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KEY71346.1 - 0.00098 19.2 0.0 0.0027 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF676 PF05057.9 KEY71346.1 - 0.0015 17.8 0.0 0.0033 16.7 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KEY71346.1 - 0.038 13.5 0.1 0.077 12.5 0.1 1.4 1 0 0 1 1 1 0 PGAP1-like protein TPR_7 PF13176.1 KEY71346.1 - 0.064 13.0 0.0 0.5 10.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat AFG1_ATPase PF03969.11 KEY71347.1 - 1.9e-92 309.9 0.0 4.2e-87 292.2 0.0 2.4 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 KEY71347.1 - 1.4e-05 25.2 0.3 0.019 14.9 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 KEY71347.1 - 0.0037 17.3 0.0 0.016 15.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 KEY71347.1 - 0.0041 17.1 0.0 0.035 14.1 0.0 2.4 2 1 0 2 2 2 1 Sigma-54 interaction domain Bac_DnaA PF00308.13 KEY71347.1 - 0.0082 15.8 0.1 0.2 11.2 0.1 2.5 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_5 PF07728.9 KEY71347.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 KEY71347.1 - 0.022 14.9 0.0 0.056 13.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KEY71347.1 - 0.041 13.5 0.0 0.11 12.1 0.0 1.8 1 1 0 1 1 1 0 NACHT domain APS_kinase PF01583.15 KEY71347.1 - 0.047 13.3 0.0 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Cupredoxin_1 PF13473.1 KEY71347.1 - 0.05 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Cupredoxin-like domain RNA_helicase PF00910.17 KEY71347.1 - 0.075 13.2 0.0 0.24 11.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF2457 PF10446.4 KEY71347.1 - 9.1 4.8 14.0 15 4.1 9.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1295 PF06966.7 KEY71348.1 - 6.5e-20 71.4 0.0 8.4e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 KEY71348.1 - 6.7e-07 28.1 2.4 1.9e-06 26.7 1.6 1.7 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family UPF0104 PF03706.8 KEY71348.1 - 9.2e-05 21.8 2.1 0.00014 21.2 1.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) Steroid_dh PF02544.11 KEY71348.1 - 0.00012 21.8 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase SH3_9 PF14604.1 KEY71349.1 - 2.8e-11 42.8 0.0 4.4e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KEY71349.1 - 1.2e-09 37.3 0.0 1.9e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KEY71349.1 - 2.5e-06 26.8 0.0 4.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SKG6 PF08693.5 KEY71349.1 - 0.0003 20.0 0.1 0.00053 19.2 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.1 KEY71349.1 - 0.0026 17.4 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 Glycophorin_A PF01102.13 KEY71349.1 - 0.0063 16.2 4.8 0.028 14.1 2.3 2.8 2 1 0 2 2 2 1 Glycophorin A DUF1049 PF06305.6 KEY71349.1 - 0.0073 15.7 0.3 0.012 15.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) EphA2_TM PF14575.1 KEY71349.1 - 0.014 15.8 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF912 PF06024.7 KEY71349.1 - 0.022 14.8 0.0 0.059 13.4 0.0 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Herpes_gE PF02480.11 KEY71349.1 - 0.043 12.0 0.1 0.063 11.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Myc_target_1 PF15179.1 KEY71349.1 - 0.056 13.0 0.5 0.16 11.5 0.1 1.9 1 1 0 1 1 1 0 Myc target protein 1 TMEM154 PF15102.1 KEY71349.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Conotoxin PF02950.12 KEY71349.1 - 0.14 12.9 0.0 0.3 11.8 0.0 1.5 1 0 0 1 1 1 0 Conotoxin Ctr PF04145.10 KEY71349.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Ctr copper transporter family CVNH PF08881.5 KEY71350.1 - 3.7e-13 49.6 0.0 5.1e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 CVNH domain Toxin_22 PF08092.6 KEY71350.1 - 0.21 11.4 0.3 0.21 11.4 0.2 1.7 2 0 0 2 2 2 0 Magi peptide toxin family adh_short PF00106.20 KEY71352.1 - 3.1e-60 202.8 7.7 1.4e-30 106.4 0.4 3.1 3 0 0 3 3 3 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 KEY71352.1 - 1.7e-31 108.1 0.0 4.5e-31 106.7 0.0 1.7 2 0 0 2 2 2 1 MaoC like domain KR PF08659.5 KEY71352.1 - 2.3e-29 102.3 1.2 1.5e-13 50.8 0.1 3.2 3 0 0 3 3 3 2 KR domain MaoC_dehydrat_N PF13452.1 KEY71352.1 - 1.2e-09 38.0 0.0 1.2e-07 31.6 0.0 2.6 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.14 KEY71352.1 - 0.00093 18.3 0.7 0.005 15.9 0.2 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AAA_17 PF13207.1 KEY71353.1 - 4.9e-06 27.3 0.2 3.2e-05 24.7 0.2 2.2 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 KEY71353.1 - 9.1e-06 24.8 0.0 1.3e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain SRP54 PF00448.17 KEY71353.1 - 3.4e-05 23.3 0.0 4.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PRK PF00485.13 KEY71353.1 - 8.7e-05 22.1 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 KEY71353.1 - 0.00047 20.4 0.0 0.0038 17.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KEY71353.1 - 0.0013 17.8 0.0 0.0023 17.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 KEY71353.1 - 0.0044 17.0 0.4 0.01 15.8 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain UPF0079 PF02367.12 KEY71353.1 - 0.0065 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 ArgK PF03308.11 KEY71353.1 - 0.0067 15.2 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 ArgK protein cobW PF02492.14 KEY71353.1 - 0.0088 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain APS_kinase PF01583.15 KEY71353.1 - 0.012 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Arf PF00025.16 KEY71353.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Thymidylate_kin PF02223.12 KEY71353.1 - 0.018 14.4 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_30 PF13604.1 KEY71353.1 - 0.02 14.4 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KEY71353.1 - 0.03 14.2 0.0 0.064 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 KEY71353.1 - 0.031 13.9 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 KEY71353.1 - 0.031 14.1 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KEY71353.1 - 0.05 13.3 0.1 0.08 12.6 0.1 1.2 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.1 KEY71353.1 - 0.081 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KEY71353.1 - 0.082 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MobB PF03205.9 KEY71353.1 - 0.1 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 KEY71353.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ECM11 PF15463.1 KEY71354.1 - 1.6e-41 141.8 10.3 1.6e-41 141.8 7.2 2.4 3 1 0 3 3 3 1 Extracellular mutant protein 11 zf-U11-48K PF05253.7 KEY71355.1 - 0.048 13.3 0.3 0.12 12.0 0.2 1.8 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger F-box-like PF12937.2 KEY71355.1 - 0.12 12.1 2.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 F-box-like Pyridox_oxidase PF01243.15 KEY71356.1 - 1.4e-08 34.6 0.0 2.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2686 PF10887.3 KEY71356.1 - 0.11 11.2 0.0 0.35 9.5 0.0 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF2686) TP_methylase PF00590.15 KEY71357.1 - 5.1e-19 68.8 0.0 9.3e-19 67.9 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-C2H2_jaz PF12171.3 KEY71358.1 - 1.9e-05 24.6 0.6 3.5e-05 23.8 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEY71358.1 - 3.3e-05 23.9 0.6 6e-05 23.1 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1777 PF08648.7 KEY71358.1 - 3.7e-05 23.5 11.4 3.7e-05 23.5 7.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) zf-DBF PF07535.7 KEY71358.1 - 0.019 14.6 0.2 0.037 13.6 0.1 1.5 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_2 PF12756.2 KEY71358.1 - 0.028 14.5 0.1 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 KEY71358.1 - 0.062 12.8 0.3 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 U1 zinc finger CCDC84 PF14968.1 KEY71358.1 - 0.075 12.5 6.0 0.057 12.9 3.5 1.4 1 1 0 1 1 1 0 Coiled coil protein 84 zf-C2H2 PF00096.21 KEY71358.1 - 0.086 13.2 0.4 0.17 12.2 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 KEY71358.1 - 0.091 13.0 0.7 0.17 12.1 0.5 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain AKAP95 PF04988.7 KEY71358.1 - 0.5 10.1 11.6 10 5.8 8.0 2.4 1 1 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) FmrO PF07091.6 KEY71358.1 - 0.58 9.1 5.8 0.98 8.3 4.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) OmpH PF03938.9 KEY71358.1 - 1.8 8.5 15.5 1 9.3 6.8 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) UQ_con PF00179.21 KEY71359.1 - 3.3e-36 123.8 0.0 3.9e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEY71359.1 - 0.025 14.3 0.0 0.042 13.6 0.0 1.5 1 1 0 1 1 1 0 Prokaryotic E2 family B Glyco_trans_1_4 PF13692.1 KEY71360.1 - 2e-22 79.8 0.0 5.5e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KEY71360.1 - 0.0002 21.5 0.0 0.00043 20.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Cation_efflux PF01545.16 KEY71361.1 - 1.3e-59 201.6 0.5 1.9e-59 201.1 0.4 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 KEY71361.1 - 0.0041 16.1 26.6 0.0041 16.1 18.4 3.5 1 1 1 3 3 3 2 ZIP Zinc transporter GPCR_chapero_1 PF11904.3 KEY71361.1 - 0.72 8.9 5.5 1.7 7.6 3.8 1.6 1 0 0 1 1 1 0 GPCR-chaperone Mito_carr PF00153.22 KEY71362.1 - 4.6e-57 189.7 4.7 8.6e-20 70.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein His_Phos_1 PF00300.17 KEY71363.1 - 1.6e-09 38.0 0.0 1.7e-06 28.2 0.0 3.0 3 1 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) Peptidase_C13 PF01650.13 KEY71364.1 - 2.3e-40 138.5 0.1 3e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family TFIIIC_delta PF12657.2 KEY71365.1 - 1.5e-16 60.6 0.0 4.1e-16 59.1 0.0 1.8 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term SUR7 PF06687.7 KEY71366.1 - 3.6e-27 95.3 0.1 4.4e-27 95.0 0.1 1.0 1 0 0 1 1 1 1 SUR7/PalI family SseC PF04888.7 KEY71366.1 - 0.043 13.1 0.2 0.043 13.1 0.1 2.2 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family Fig1 PF12351.3 KEY71366.1 - 0.27 11.0 6.0 0.022 14.6 0.7 1.7 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Pex24p PF06398.6 KEY71366.1 - 9.4 4.9 5.7 19 3.9 0.0 2.8 3 0 0 3 3 3 0 Integral peroxisomal membrane peroxin Ras PF00071.17 KEY71368.1 - 4.6e-40 136.6 0.0 8.9e-38 129.2 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KEY71368.1 - 1.3e-17 64.3 0.0 1.8e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEY71368.1 - 2.1e-10 40.1 0.0 3.3e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KEY71368.1 - 0.0029 17.5 0.0 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KEY71368.1 - 0.02 14.1 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KEY71368.1 - 0.032 13.3 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_33 PF13671.1 KEY71368.1 - 0.039 13.8 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2411 PF10304.4 KEY71368.1 - 0.061 12.8 0.3 0.12 11.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) AAA_22 PF13401.1 KEY71368.1 - 0.083 13.0 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KEY71368.1 - 0.12 11.9 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KEY71368.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KEY71368.1 - 0.15 11.9 0.3 0.42 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sec63 PF02889.11 KEY71369.1 - 1.5e-153 510.5 0.0 2.5e-97 325.8 0.1 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KEY71369.1 - 2e-53 180.3 0.1 7.9e-28 97.0 0.3 3.8 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY71369.1 - 7.2e-17 61.0 0.0 2.8e-07 30.3 0.0 3.3 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 KEY71369.1 - 1.5e-15 57.4 0.0 2.2e-06 27.6 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KEY71369.1 - 7.2e-08 32.6 0.5 0.0078 16.3 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_19 PF13245.1 KEY71369.1 - 4.7e-05 23.0 2.6 0.1 12.3 0.0 3.8 4 0 0 4 4 4 2 Part of AAA domain IstB_IS21 PF01695.12 KEY71369.1 - 0.014 14.7 0.2 19 4.5 0.0 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_10 PF12846.2 KEY71369.1 - 0.064 12.6 0.0 22 4.3 0.0 3.4 3 1 1 4 4 4 0 AAA-like domain Longin PF13774.1 KEY71370.1 - 8.8e-16 57.2 0.0 1.5e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KEY71370.1 - 2.1e-14 52.8 0.6 3.2e-14 52.2 0.4 1.2 1 0 0 1 1 1 1 Synaptobrevin Tbf5 PF06331.7 KEY71370.1 - 0.14 11.9 0.3 0.26 11.0 0.2 1.4 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 NB-ARC PF00931.17 KEY71372.1 - 6.5e-15 54.7 0.0 9.9e-15 54.1 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KEY71372.1 - 9.8e-06 25.7 0.0 2.3e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain PNP_UDP_1 PF01048.15 KEY71372.1 - 0.00016 20.7 0.0 0.0013 17.7 0.0 2.2 2 0 0 2 2 2 1 Phosphorylase superfamily TPR_12 PF13424.1 KEY71372.1 - 0.00049 19.9 3.8 0.049 13.5 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 KEY71372.1 - 0.00056 19.7 1.4 1 9.3 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEY71372.1 - 0.0095 16.2 1.7 9 6.7 0.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat AAA_25 PF13481.1 KEY71372.1 - 0.037 13.4 0.0 0.52 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Apc3 PF12895.2 KEY71372.1 - 0.037 14.1 0.9 1 9.5 0.4 2.9 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KEY71372.1 - 0.1 12.4 0.1 0.1 12.4 0.1 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 KEY71372.1 - 0.62 10.2 3.3 6.6 6.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEY71373.1 - 2.3e-24 84.5 15.2 0.0087 15.9 0.1 7.1 1 1 6 7 7 7 7 Tetratricopeptide repeat Apc3 PF12895.2 KEY71373.1 - 4e-18 65.3 18.0 1.5e-05 25.0 0.0 4.5 1 1 4 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KEY71373.1 - 6e-17 61.3 24.3 5.7e-06 26.1 1.8 4.4 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 KEY71373.1 - 1.4e-16 60.6 10.4 0.58 10.8 0.1 7.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 KEY71373.1 - 1.5e-16 58.8 16.9 0.042 13.6 0.1 7.2 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_19 PF14559.1 KEY71373.1 - 1.7e-14 53.9 16.1 0.03 14.6 0.4 7.0 1 1 6 7 7 7 6 Tetratricopeptide repeat TPR_20 PF14561.1 KEY71373.1 - 3e-11 43.2 28.0 0.083 13.0 0.2 7.0 1 1 6 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 KEY71373.1 - 3.1e-10 39.7 15.2 2.8 8.8 0.1 7.1 4 2 3 7 7 7 1 Tetratricopeptide repeat PPR_3 PF13812.1 KEY71373.1 - 2.2e-08 33.7 14.8 0.49 10.8 0.0 6.9 7 0 0 7 7 7 1 Pentatricopeptide repeat domain TPR_6 PF13174.1 KEY71373.1 - 3e-08 33.5 3.5 2.8 8.5 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEY71373.1 - 3.2e-07 29.6 5.3 2.5 8.0 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat PPR PF01535.15 KEY71373.1 - 4.4e-07 29.4 7.7 7.6 6.7 0.0 6.6 7 0 0 7 7 7 0 PPR repeat Paf67 PF10255.4 KEY71373.1 - 1.7e-06 27.1 0.6 0.65 8.8 0.0 4.6 1 1 5 6 6 6 1 RNA polymerase I-associated factor PAF67 Plectin PF00681.15 KEY71373.1 - 2.4e-06 26.9 5.6 11 5.5 0.0 6.4 6 1 0 6 6 6 0 Plectin repeat PPR_1 PF12854.2 KEY71373.1 - 1.5e-05 24.3 4.0 1.8 8.1 0.1 6.5 7 0 0 7 7 7 1 PPR repeat TPR_2 PF07719.12 KEY71373.1 - 4.6e-05 23.0 8.8 43 4.3 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat ATP13 PF12921.2 KEY71373.1 - 0.00013 21.3 4.2 23 4.3 0.0 5.7 3 2 2 6 6 6 0 Mitochondrial ATPase expression PBC PF03792.8 KEY71373.1 - 0.00057 19.6 31.2 2.1 7.9 0.2 6.8 1 1 6 7 7 7 3 PBC domain P53_tetramer PF07710.6 KEY71373.1 - 0.00085 18.3 2.4 60 2.8 0.0 6.2 7 0 0 7 7 7 0 P53 tetramerisation motif Bombinin PF05298.6 KEY71373.1 - 0.0012 18.2 27.6 0.16 11.4 1.5 5.6 1 1 4 5 5 5 3 Bombinin Syntaxin-18_N PF10496.4 KEY71373.1 - 0.002 17.9 6.9 5.1 7.0 0.1 5.0 4 1 1 5 5 5 0 SNARE-complex protein Syntaxin-18 N-terminus MYCBPAP PF14646.1 KEY71373.1 - 0.0053 15.5 8.0 0.8 8.3 0.1 3.9 1 1 2 4 4 4 1 MYCBP-associated protein family DUF4248 PF14053.1 KEY71373.1 - 0.011 15.2 3.1 95 2.6 0.0 5.8 7 0 0 7 7 7 0 Domain of unknown function (DUF4248) TPR_1 PF00515.23 KEY71373.1 - 0.014 14.9 3.5 86 2.9 0.0 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat PPR_2 PF13041.1 KEY71373.1 - 0.017 15.0 5.8 26 4.9 0.0 5.8 7 0 0 7 7 6 0 PPR repeat family TPR_17 PF13431.1 KEY71373.1 - 0.043 14.0 4.2 71 3.9 0.0 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat E2F_TDP PF02319.15 KEY71373.1 - 0.05 13.1 14.0 11 5.6 0.1 5.3 2 2 4 6 6 6 0 E2F/DP family winged-helix DNA-binding domain Med14 PF08638.6 KEY71373.1 - 0.058 12.6 1.0 28 3.8 0.0 3.5 1 1 1 3 3 3 0 Mediator complex subunit MED14 TPR_4 PF07721.9 KEY71373.1 - 0.059 13.8 4.5 4.4 8.0 0.1 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF1043 PF06295.7 KEY71373.1 - 0.087 12.4 17.1 4.4 6.9 0.8 4.1 1 1 2 4 4 4 0 Protein of unknown function (DUF1043) NIR_SIR PF01077.17 KEY71373.1 - 0.38 10.1 5.2 94 2.3 0.0 4.8 2 1 3 5 5 5 0 Nitrite and sulphite reductase 4Fe-4S domain Cep57_CLD_2 PF14197.1 KEY71373.1 - 9.5 6.2 26.8 4.7 7.2 0.8 6.1 2 2 5 7 7 7 0 Centrosome localisation domain of PPC89 Glyco_hydro_43 PF04616.9 KEY71374.1 - 1.3e-05 24.4 0.1 1.9e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF2893 PF11459.3 KEY71377.1 - 0.098 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknwon function (DUF2893) G-gamma PF00631.17 KEY71377.1 - 0.19 11.5 1.7 20 4.9 0.0 2.6 2 0 0 2 2 2 0 GGL domain DivIC PF04977.10 KEY71377.1 - 6.5 6.3 7.0 3.3 7.2 2.6 2.0 2 0 0 2 2 2 0 Septum formation initiator SUR7 PF06687.7 KEY71378.1 - 1.7e-21 76.7 8.4 2e-21 76.5 5.8 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 KEY71378.1 - 0.015 15.2 8.6 0.03 14.2 5.9 1.5 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 DUF973 PF06157.6 KEY71378.1 - 0.026 13.4 11.1 0.04 12.8 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF2207 PF09972.4 KEY71378.1 - 1 7.8 4.0 4.2 5.8 2.8 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) YoqO PF14037.1 KEY71378.1 - 1.9 8.6 12.3 1.7 8.7 0.1 3.0 2 1 1 3 3 3 0 YoqO-like protein DUF3112 PF11309.3 KEY71378.1 - 3.2 7.5 12.2 0.61 9.8 5.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) CorA PF01544.13 KEY71379.1 - 8.4e-06 25.0 0.1 1.5e-05 24.1 0.1 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DEAD PF00270.24 KEY71380.1 - 1.2e-42 145.2 0.0 4.4e-40 136.9 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY71380.1 - 4.7e-23 80.8 0.2 1.6e-22 79.1 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEY71380.1 - 0.0076 16.0 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KEY71380.1 - 0.033 12.9 0.0 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain p450 PF00067.17 KEY71382.1 - 1e-49 169.3 0.0 1.3e-49 168.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KEY71385.1 - 5.5e-19 68.0 14.4 5.5e-19 68.0 10.0 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY71385.1 - 0.002 16.8 2.6 0.0046 15.5 1.8 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter IncA PF04156.9 KEY71385.1 - 0.09 12.3 1.2 0.17 11.4 0.8 1.5 1 0 0 1 1 1 0 IncA protein DUF1980 PF09323.5 KEY71385.1 - 0.19 11.4 0.5 0.41 10.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) PCI PF01399.22 KEY71386.1 - 0.0042 17.3 0.1 4 7.7 0.0 2.5 2 0 0 2 2 2 2 PCI domain SUN PF03856.8 KEY71387.1 - 7.2e-71 238.3 13.2 9.7e-71 237.9 9.1 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) BSP_II PF05432.6 KEY71387.1 - 1.2 8.3 24.9 0.15 11.2 14.3 1.6 1 1 1 2 2 2 0 Bone sialoprotein II (BSP-II) Sporozoite_P67 PF05642.6 KEY71387.1 - 1.5 6.5 24.0 0.0054 14.6 9.6 1.7 1 1 1 2 2 2 0 Sporozoite P67 surface antigen Hamartin PF04388.7 KEY71387.1 - 1.7 7.2 14.2 1.9 7.0 9.9 1.1 1 0 0 1 1 1 0 Hamartin protein GTP_EFTU PF00009.22 KEY71388.1 - 6.5e-46 156.1 0.0 1.2e-45 155.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KEY71388.1 - 4.3e-19 68.1 0.0 8e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KEY71388.1 - 3e-11 43.0 0.0 2.4e-10 40.1 0.0 2.3 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KEY71388.1 - 0.0065 16.5 0.1 0.035 14.2 0.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu domain 2 COPI_assoc PF08507.5 KEY71389.1 - 2.4e-36 124.4 3.0 3.3e-36 124.0 2.1 1.2 1 1 0 1 1 1 1 COPI associated protein UCR_Fe-S_N PF10399.4 KEY71389.1 - 0.015 14.4 0.4 0.015 14.4 0.3 2.0 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Senescence PF06911.7 KEY71390.1 - 0.0098 15.6 2.5 0.018 14.7 1.7 1.4 1 1 0 1 1 1 1 Senescence-associated protein Glycoprotein_B PF00606.13 KEY71390.1 - 0.049 11.6 1.5 0.053 11.5 1.1 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B Chlorosome_CsmC PF11098.3 KEY71390.1 - 0.17 11.5 4.1 0.21 11.3 2.8 1.2 1 0 0 1 1 1 0 Chlorosome envelope protein C DEAD PF00270.24 KEY71391.1 - 1.4e-41 141.8 0.1 2.8e-41 140.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY71391.1 - 2.6e-18 65.6 0.0 5.8e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KEY71391.1 - 1.2e-16 59.9 0.0 2.7e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KEY71391.1 - 0.00085 19.1 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PPR_2 PF13041.1 KEY71392.1 - 2.4e-49 165.0 5.1 9e-10 38.3 0.0 15.1 11 3 5 16 16 16 13 PPR repeat family PPR_3 PF13812.1 KEY71392.1 - 3e-26 89.4 20.2 0.0021 18.2 0.0 16.4 18 0 0 18 18 18 5 Pentatricopeptide repeat domain PPR PF01535.15 KEY71392.1 - 1.2e-24 84.4 17.2 0.00055 19.7 0.0 13.4 17 0 0 17 17 17 6 PPR repeat PPR_1 PF12854.2 KEY71392.1 - 3.1e-22 77.7 0.1 2.9e-08 33.0 0.0 10.8 11 0 0 11 11 11 3 PPR repeat RPM2 PF08579.6 KEY71392.1 - 1.8e-06 28.0 0.0 0.0011 19.0 0.0 4.3 4 1 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_7 PF13176.1 KEY71392.1 - 0.0038 16.8 0.2 4.6 7.2 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat ECSIT PF06239.6 KEY71392.1 - 0.028 13.2 0.0 6.9 5.4 0.0 2.8 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway ATP13 PF12921.2 KEY71392.1 - 0.073 12.4 0.4 8.5 5.7 0.0 3.7 4 0 0 4 4 4 0 Mitochondrial ATPase expression GHMP_kinases_N PF00288.21 KEY71393.1 - 6.9e-15 54.8 3.0 2.1e-14 53.3 2.1 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KEY71393.1 - 1e-08 35.2 0.0 2.2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Viral_P18 PF04521.8 KEY71393.1 - 0.11 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein MGAT2 PF05060.9 KEY71394.1 - 0.041 12.8 0.0 0.047 12.5 0.0 1.0 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) Aldedh PF00171.17 KEY71395.1 - 3.2e-134 447.7 0.0 3.6e-134 447.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KEY71395.1 - 9.4e-08 31.1 0.0 1.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KEY71395.1 - 0.023 13.9 0.0 2.8 7.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) RRM_6 PF14259.1 KEY71396.1 - 3.4e-06 26.9 0.0 1.4e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEY71396.1 - 1.4e-05 24.6 0.0 0.0019 17.8 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY71396.1 - 0.00077 19.2 0.0 0.0044 16.8 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.7 KEY71396.1 - 4.5 5.0 19.7 0.091 10.6 6.3 2.0 2 0 0 2 2 2 0 Nop14-like family PACT_coil_coil PF10495.4 KEY71398.1 - 0.077 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein NDT80_PhoG PF05224.7 KEY71399.1 - 5.9e-48 163.3 0.2 9e-48 162.7 0.2 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Phage_H_T_join PF05521.6 KEY71399.1 - 0.01 16.0 0.5 0.022 15.0 0.4 1.4 1 0 0 1 1 1 0 Phage head-tail joining protein Raftlin PF15250.1 KEY71399.1 - 0.055 11.9 0.0 0.086 11.3 0.0 1.2 1 0 0 1 1 1 0 Raftlin Pterin_bind PF00809.17 KEY71400.1 - 2e-64 216.8 0.0 3.3e-64 216.1 0.0 1.4 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 KEY71400.1 - 3e-41 140.1 0.0 5e-41 139.4 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.10 KEY71401.1 - 1.3e-71 241.4 1.0 1.7e-71 241.0 0.7 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KEY71401.1 - 4.1e-09 35.7 0.3 1.4e-08 34.0 0.2 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KEY71401.1 - 7.8e-06 24.9 3.8 1.3e-05 24.2 2.7 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KEY71401.1 - 0.0063 15.4 0.6 0.01 14.7 0.4 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 KEY71401.1 - 0.013 14.4 0.6 0.02 13.8 0.4 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase NanE PF04131.9 KEY71401.1 - 0.1 11.5 0.1 0.23 10.4 0.1 1.6 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase ArfGap PF01412.13 KEY71402.1 - 1.2e-32 112.1 0.1 2.3e-32 111.2 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3275 PF11679.3 KEY71402.1 - 0.31 10.6 0.1 0.31 10.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) TIM21 PF08294.6 KEY71403.1 - 5.1e-43 146.2 0.1 6.1e-43 145.9 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 KEY71403.1 - 0.00078 18.9 0.0 0.0016 17.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 zf-H2C2_2 PF13465.1 KEY71405.1 - 3.1e-08 33.5 25.0 3.3e-06 27.0 2.4 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 KEY71405.1 - 3.4e-06 27.0 20.6 0.001 19.2 2.9 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY71405.1 - 4.4e-05 23.5 16.6 0.0051 17.0 0.9 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger DUF2225 PF09986.4 KEY71405.1 - 0.34 10.3 1.0 0.83 9.0 0.7 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_6 PF13912.1 KEY71405.1 - 9.8 6.2 9.6 2.9 7.9 0.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Rad51 PF08423.6 KEY71406.1 - 8.4e-05 21.5 0.0 0.00033 19.6 0.0 2.0 1 1 0 1 1 1 1 Rad51 KaiC PF06745.8 KEY71406.1 - 0.00012 21.3 0.0 0.00025 20.2 0.0 1.5 1 0 0 1 1 1 1 KaiC RecA PF00154.16 KEY71406.1 - 0.0002 20.5 1.1 0.00049 19.2 0.1 1.9 2 1 0 2 2 2 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 KEY71406.1 - 0.00033 20.1 0.5 0.0018 17.6 0.4 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KEY71406.1 - 0.011 15.0 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 KEY71406.1 - 0.035 14.0 0.0 0.079 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 KEY71406.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain DnaB_C PF03796.10 KEY71406.1 - 0.12 11.1 0.1 8.5 5.1 0.1 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Bromodomain PF00439.20 KEY71407.1 - 2.9e-17 62.3 0.0 6.3e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 Bromodomain BTB PF00651.26 KEY71407.1 - 2.3e-06 27.5 0.0 4.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain ACBP PF00887.14 KEY71409.1 - 2e-24 85.0 0.1 2.3e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Pyr_redox_2 PF07992.9 KEY71410.1 - 2.5e-18 66.6 0.0 8.6e-18 64.9 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY71410.1 - 4.9e-08 33.2 2.1 1.1e-05 25.6 0.7 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEY71410.1 - 2e-05 23.6 7.9 0.028 13.3 0.1 3.4 2 1 0 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEY71410.1 - 0.00019 21.5 1.1 0.02 14.9 0.1 3.1 1 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEY71410.1 - 0.023 13.6 0.1 0.2 10.5 0.1 2.3 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KEY71410.1 - 0.035 13.8 4.5 7.1 6.3 0.0 4.0 4 0 0 4 4 4 0 FAD-NAD(P)-binding TrkA_N PF02254.13 KEY71410.1 - 0.13 12.2 2.1 6.3 6.8 0.0 2.9 3 0 0 3 3 3 0 TrkA-N domain End3 PF12761.2 KEY71411.1 - 4.7e-73 244.9 2.9 6.4e-73 244.5 2.0 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 KEY71411.1 - 1.9e-48 162.4 0.0 1e-46 156.9 0.0 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.1 KEY71411.1 - 7.4e-07 28.6 0.1 1.6e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KEY71411.1 - 1.4e-06 27.1 0.2 1.4e-06 27.1 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KEY71411.1 - 2.5e-05 24.3 0.0 0.00027 21.0 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KEY71411.1 - 0.00034 20.2 1.6 0.0028 17.3 0.2 2.9 3 0 0 3 3 2 1 EF-hand domain EF-hand_5 PF13202.1 KEY71411.1 - 0.013 14.8 0.2 0.013 14.8 0.1 2.6 2 0 0 2 2 2 0 EF hand Phage_sheath_1 PF04984.9 KEY71411.1 - 0.037 12.4 0.1 0.11 10.9 0.0 1.6 2 0 0 2 2 2 0 Phage tail sheath protein COG2 PF06148.6 KEY71411.1 - 0.51 10.2 4.4 0.35 10.7 0.2 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FlxA PF14282.1 KEY71411.1 - 0.88 9.5 5.4 3.7 7.5 0.1 2.8 2 1 0 3 3 3 0 FlxA-like protein Syntaxin-6_N PF09177.6 KEY71411.1 - 6.2 7.3 6.4 1.1e+02 3.3 0.2 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal NUDIX PF00293.23 KEY71412.1 - 4e-28 97.7 0.0 5.3e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_7 PF13508.1 KEY71413.1 - 3.1e-10 40.0 0.0 5.7e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEY71413.1 - 8.6e-07 28.9 0.0 1.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KEY71413.1 - 6.4e-06 26.0 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KEY71413.1 - 0.0035 17.1 0.0 0.0076 16.1 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 KEY71413.1 - 0.022 14.8 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEY71413.1 - 0.049 13.3 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein RPA_C PF08784.6 KEY71414.1 - 7.3e-20 71.2 0.1 1.8e-19 70.0 0.0 1.7 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 KEY71414.1 - 1.1e-07 31.6 0.7 4.9e-07 29.5 0.1 2.2 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain Lon_C PF05362.8 KEY71415.1 - 3.4e-67 225.7 0.5 5.9e-67 224.9 0.3 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 KEY71415.1 - 1.2e-24 86.9 0.0 5.4e-24 84.8 0.0 2.2 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 KEY71415.1 - 1.2e-23 83.9 0.3 2.6e-23 82.7 0.0 1.8 2 0 0 2 2 1 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 KEY71415.1 - 9.8e-09 35.0 0.0 3.6e-08 33.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 KEY71415.1 - 2.1e-07 30.4 0.2 8.3e-07 28.5 0.0 2.2 2 1 0 2 2 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 KEY71415.1 - 4e-06 26.9 0.4 1.7e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 KEY71415.1 - 7.1e-06 25.5 0.0 1.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.6 KEY71415.1 - 1.9e-05 24.2 0.0 6.2e-05 22.6 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEY71415.1 - 3.4e-05 24.6 0.0 9.6e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEY71415.1 - 3.4e-05 23.9 0.1 0.0034 17.5 0.0 3.4 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KEY71415.1 - 0.00023 20.3 0.1 0.00076 18.5 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 KEY71415.1 - 0.00024 21.0 0.0 0.00069 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 KEY71415.1 - 0.0015 18.2 0.1 0.0054 16.4 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KEY71415.1 - 0.0018 18.1 0.1 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KEY71415.1 - 0.0036 17.1 0.0 0.009 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEY71415.1 - 0.0048 16.3 0.0 0.013 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KEY71415.1 - 0.0059 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEY71415.1 - 0.013 14.6 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 KEY71415.1 - 0.019 14.6 0.0 0.051 13.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 KEY71415.1 - 0.02 15.0 0.0 0.06 13.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.1 KEY71415.1 - 0.021 15.1 2.4 0.12 12.7 0.0 2.6 1 1 1 2 2 2 0 AAA domain TIP49 PF06068.8 KEY71415.1 - 0.022 13.4 0.0 0.057 12.1 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus AAA_18 PF13238.1 KEY71415.1 - 0.023 15.0 0.0 0.059 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KEY71415.1 - 0.034 13.3 0.0 0.075 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 KEY71415.1 - 0.038 13.7 0.0 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 KEY71415.1 - 0.048 12.8 0.1 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_PrkA PF08298.6 KEY71415.1 - 0.059 12.0 0.0 0.88 8.1 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain NB-ARC PF00931.17 KEY71415.1 - 0.062 12.1 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain UPF0079 PF02367.12 KEY71415.1 - 0.07 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 KEY71415.1 - 0.08 12.6 0.0 0.36 10.4 0.0 2.1 1 1 1 2 2 2 0 Archaeal ATPase HflK_N PF12221.3 KEY71415.1 - 0.096 12.4 0.3 0.32 10.7 0.2 1.8 1 0 0 1 1 1 0 Bacterial membrane protein N terminal AAA_10 PF12846.2 KEY71415.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Zn_clus PF00172.13 KEY71416.1 - 7.5e-07 28.9 11.5 1.1e-06 28.3 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_2 PF07719.12 KEY71417.1 - 0.23 11.4 2.4 0.38 10.7 0.1 2.4 2 1 0 3 3 3 0 Tetratricopeptide repeat eIF3g PF12353.3 KEY71418.1 - 4.1e-45 152.8 1.6 6.5e-45 152.1 1.1 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 KEY71418.1 - 1.3e-15 56.7 0.1 2.5e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY71418.1 - 9.3e-13 47.9 0.1 1.7e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY71418.1 - 7.1e-08 32.1 0.1 1.6e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NIDO PF06119.9 KEY71418.1 - 0.14 12.8 0.0 0.29 11.8 0.0 1.5 1 0 0 1 1 1 0 Nidogen-like CYSTM PF12734.2 KEY71419.1 - 0.14 12.2 66.4 1.5e+04 -12.3 46.0 5.4 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance DUF221 PF02714.10 KEY71420.1 - 1e-95 320.3 25.6 1e-95 320.3 17.7 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KEY71420.1 - 8.2e-41 139.1 0.6 8.2e-41 139.1 0.4 3.3 4 1 2 6 6 6 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KEY71420.1 - 1e-18 66.9 0.0 5.2e-18 64.7 0.0 2.1 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 KEY71420.1 - 1.5e-10 41.4 11.6 2.3e-05 24.7 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4463) SRP_SPB PF02978.14 KEY71420.1 - 0.068 13.4 2.4 0.19 11.9 1.7 1.7 1 0 0 1 1 1 0 Signal peptide binding domain Herpes_capsid PF06112.6 KEY71420.1 - 5.3 7.0 8.9 1.6e+02 2.2 0.0 3.4 3 0 0 3 3 3 0 Gammaherpesvirus capsid protein Abhydrolase_6 PF12697.2 KEY71421.1 - 9.6e-29 100.8 0.0 1.6e-27 96.9 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY71421.1 - 4.1e-16 59.2 0.0 5.4e-13 49.0 0.0 2.7 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY71421.1 - 3.3e-14 52.8 0.0 1.6e-09 37.6 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF915 PF06028.6 KEY71421.1 - 1.1e-05 24.7 0.0 2.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 KEY71421.1 - 0.00013 21.5 0.0 0.00024 20.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Lipase_3 PF01764.20 KEY71421.1 - 0.0041 16.7 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.8 KEY71421.1 - 0.0062 16.1 0.0 0.038 13.5 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KEY71421.1 - 0.0093 16.2 0.1 0.025 14.8 0.0 1.8 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.11 KEY71421.1 - 0.011 15.2 0.0 1.3 8.4 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 KEY71421.1 - 0.011 15.5 0.2 0.066 13.0 0.0 2.4 3 0 0 3 3 3 0 Putative lysophospholipase DUF2305 PF10230.4 KEY71421.1 - 0.032 13.6 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Chlorophyllase2 PF12740.2 KEY71421.1 - 0.08 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Ser_hydrolase PF06821.8 KEY71421.1 - 0.096 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase PGAP1 PF07819.8 KEY71421.1 - 0.18 11.3 0.0 0.46 10.0 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein Spo7 PF03907.8 KEY71423.1 - 2.6e-67 226.4 0.2 3.4e-67 226.0 0.1 1.1 1 0 0 1 1 1 1 Spo7-like protein Fringe PF02434.11 KEY71424.1 - 0.011 15.0 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Fringe-like TRM PF02005.11 KEY71426.1 - 1.2e-105 353.5 0.0 1.1e-102 343.8 0.0 2.1 1 1 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 KEY71426.1 - 2.3e-05 24.4 0.0 5.9e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KEY71426.1 - 0.0015 17.6 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Met_10 PF02475.11 KEY71426.1 - 0.0025 17.4 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 KEY71426.1 - 0.07 13.7 0.1 0.18 12.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain DAGK_cat PF00781.19 KEY71427.1 - 6.4e-07 28.8 0.0 1.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Lectin_leg-like PF03388.8 KEY71427.1 - 0.0026 16.9 0.0 0.0045 16.1 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family ABC_tran PF00005.22 KEY71428.1 - 2.8e-44 150.7 0.2 1.2e-22 80.6 0.0 3.2 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KEY71428.1 - 1.2e-12 48.4 4.3 0.027 14.4 0.0 4.2 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 KEY71428.1 - 4.1e-09 35.9 0.0 0.011 15.0 0.0 3.4 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_tran_2 PF12848.2 KEY71428.1 - 2e-07 30.7 2.2 8.7e-07 28.7 1.6 2.1 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 KEY71428.1 - 1.6e-06 27.5 1.8 0.017 14.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KEY71428.1 - 7.7e-06 25.8 0.0 0.026 14.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 KEY71428.1 - 1.5e-05 25.1 0.6 0.31 11.1 0.1 3.5 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KEY71428.1 - 2.3e-05 25.2 0.4 0.29 11.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KEY71428.1 - 7.5e-05 21.9 1.1 0.11 11.6 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 KEY71428.1 - 0.00012 21.7 0.1 0.56 9.9 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KEY71428.1 - 0.00036 20.5 9.3 0.049 13.6 0.1 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 KEY71428.1 - 0.00038 20.7 1.0 0.68 10.2 0.1 2.8 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KEY71428.1 - 0.0008 19.8 0.9 0.06 13.8 0.0 2.8 2 1 0 2 2 2 1 Miro-like protein AAA_5 PF07728.9 KEY71428.1 - 0.0033 17.1 1.0 1.3 8.7 0.1 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_15 PF13175.1 KEY71428.1 - 0.0034 16.4 0.2 10 5.0 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_33 PF13671.1 KEY71428.1 - 0.0055 16.5 1.3 0.76 9.6 0.2 2.8 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 KEY71428.1 - 0.014 15.2 10.8 0.027 14.3 0.5 3.1 4 0 0 4 4 4 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 KEY71428.1 - 0.018 15.2 0.2 6.9 6.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ArgK PF03308.11 KEY71428.1 - 0.018 13.7 1.6 0.18 10.5 0.1 2.3 2 0 0 2 2 2 0 ArgK protein NACHT PF05729.7 KEY71428.1 - 0.02 14.5 0.3 6.4 6.4 0.1 2.5 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.13 KEY71428.1 - 0.03 13.8 0.4 2.4 7.5 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 KEY71428.1 - 0.035 13.1 0.3 1.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ATP-synt_ab PF00006.20 KEY71428.1 - 0.038 13.4 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.1 KEY71428.1 - 0.094 12.6 6.2 0.17 11.8 0.1 3.0 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.1 KEY71428.1 - 0.099 12.9 16.0 1 9.6 0.2 4.1 4 0 0 4 4 4 0 AAA domain AAA_10 PF12846.2 KEY71428.1 - 0.2 11.0 2.2 6.8 6.0 0.1 2.7 3 0 0 3 3 3 0 AAA-like domain Vfa1 PF08432.5 KEY71428.1 - 0.87 9.5 5.0 0.17 11.8 0.3 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 AAA_13 PF13166.1 KEY71428.1 - 1.3 7.3 16.5 0.23 9.8 0.1 3.6 4 0 0 4 4 4 0 AAA domain DSPc PF00782.15 KEY71429.1 - 4.7e-24 84.4 0.0 1.3e-22 79.8 0.0 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEY71429.1 - 0.00024 20.5 0.0 0.00038 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase UAA PF08449.6 KEY71430.1 - 1.7e-72 243.9 0.6 7.8e-72 241.7 0.4 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KEY71430.1 - 1.1e-08 35.1 22.8 1.6e-06 28.2 2.5 3.5 4 0 0 4 4 4 3 EamA-like transporter family Nuc_sug_transp PF04142.10 KEY71430.1 - 3.4e-06 26.3 2.7 0.014 14.5 0.3 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 KEY71430.1 - 5e-05 23.4 17.7 0.00029 21.0 3.0 3.3 3 1 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 KEY71430.1 - 0.002 17.7 9.9 0.002 17.7 6.9 2.7 3 1 0 3 3 3 1 Triose-phosphate Transporter family SPW PF03779.9 KEY71430.1 - 0.024 14.0 1.8 0.21 10.9 0.2 2.9 2 0 0 2 2 2 0 SPW repeat UPF0546 PF10639.4 KEY71430.1 - 0.089 12.6 5.5 0.035 13.9 1.5 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 KH_1 PF00013.24 KEY71431.1 - 5.8e-38 128.3 12.1 3.3e-14 52.2 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KEY71431.1 - 2.7e-30 103.4 12.6 7.7e-11 41.3 0.5 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KEY71431.1 - 1.1e-10 40.9 8.4 0.001 18.5 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KEY71431.1 - 1.4e-08 34.1 3.1 0.037 13.6 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KEY71431.1 - 7.1e-05 22.5 4.5 0.74 9.6 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain dUTPase PF00692.14 KEY71431.1 - 0.071 12.5 0.2 4.8 6.6 0.0 3.0 3 0 0 3 3 3 0 dUTPase DUF664 PF04978.7 KEY71432.1 - 1.2 9.3 6.3 1.1 9.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF664) RabGAP-TBC PF00566.13 KEY71433.1 - 3.6e-29 101.7 0.2 6.3e-29 100.9 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 KEY71434.1 - 9.8e-58 195.3 0.0 1.3e-57 194.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY71434.1 - 8.2e-19 67.6 0.0 2e-18 66.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY71434.1 - 0.0017 17.3 0.2 0.42 9.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 KEY71434.1 - 0.05 12.6 0.1 0.16 11.0 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-B_box PF00643.19 KEY71435.1 - 5.2 7.0 7.9 8.6 6.3 5.5 1.3 1 0 0 1 1 1 0 B-box zinc finger Glucosamine_iso PF01182.15 KEY71436.1 - 5.3e-57 192.7 0.0 6.5e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF3176 PF11374.3 KEY71437.1 - 8.3e-31 106.1 1.4 1.5e-30 105.2 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) GMC_oxred_N PF00732.14 KEY71438.1 - 9.6e-39 133.2 0.0 1.3e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY71438.1 - 4.8e-06 26.9 0.0 8.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Nt_Gln_amidase PF09764.4 KEY71438.1 - 0.25 10.5 0.0 0.56 9.4 0.0 1.5 2 0 0 2 2 2 0 N-terminal glutamine amidase HTH_6 PF01418.12 KEY71439.1 - 0.031 13.9 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Lyase_1 PF00206.15 KEY71441.1 - 6.5e-36 124.1 0.0 1e-35 123.4 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 KEY71441.1 - 1.4e-09 37.8 0.5 3.9e-09 36.4 0.4 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DDE_Tnp_1_7 PF13843.1 KEY71443.1 - 2.7e-36 125.3 0.0 4.9e-17 62.0 0.0 2.1 1 1 1 2 2 2 2 Transposase IS4 DUF4510 PF14971.1 KEY71443.1 - 0.039 14.1 0.4 0.069 13.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) DUF3425 PF11905.3 KEY71444.1 - 1.2e-25 89.9 1.7 4.4e-25 88.1 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) HET PF06985.6 KEY71445.1 - 8.1e-24 84.3 0.1 2.2e-23 82.9 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank PF00023.25 KEY71445.1 - 8.8e-24 82.0 0.4 5e-08 32.3 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 KEY71445.1 - 1.3e-21 76.6 0.0 5.9e-13 48.9 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEY71445.1 - 1.6e-17 63.1 1.1 3.4e-06 27.1 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY71445.1 - 9.8e-15 53.2 0.5 0.00017 21.4 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 KEY71445.1 - 1.9e-10 40.9 1.1 1.7e-05 25.1 0.0 3.7 4 1 0 4 4 4 2 Ankyrin repeats (many copies) NPV_P10 PF05531.7 KEY71446.1 - 0.025 14.7 0.5 0.035 14.3 0.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein MULE PF10551.4 KEY71447.1 - 5.1e-16 58.6 0.2 2.3e-15 56.5 0.0 2.2 2 0 0 2 2 2 1 MULE transposase domain FAR1 PF03101.10 KEY71447.1 - 6.2e-08 33.0 0.2 1.7e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain Transposase_mut PF00872.13 KEY71447.1 - 0.0006 18.4 0.0 0.0012 17.5 0.0 1.4 1 0 0 1 1 1 1 Transposase, Mutator family Actin PF00022.14 KEY71449.1 - 6.5e-16 57.7 0.0 1.8e-13 49.7 0.0 2.1 2 0 0 2 2 2 2 Actin DUF500 PF04366.7 KEY71450.1 - 5e-26 90.5 0.0 8.8e-26 89.8 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) LRR_4 PF12799.2 KEY71451.1 - 0.14 11.8 0.9 5.3 6.7 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) CUE PF02845.11 KEY71451.1 - 0.14 11.6 0.1 0.32 10.5 0.1 1.6 1 0 0 1 1 1 0 CUE domain F-box PF00646.28 KEY71451.1 - 0.17 11.6 1.2 0.49 10.1 0.1 2.3 3 0 0 3 3 3 0 F-box domain Fungal_trans PF04082.13 KEY71453.1 - 4.5e-18 65.0 1.6 7.6e-18 64.3 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 KEY71453.1 - 2.2e-07 30.8 7.8 1.3e-05 25.2 0.8 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KEY71453.1 - 3.8e-05 23.7 14.2 0.0015 18.7 4.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 KEY71453.1 - 0.0016 18.5 3.8 0.003 17.6 2.6 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KEY71453.1 - 0.021 15.1 16.8 0.051 13.9 4.7 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KEY71453.1 - 0.73 10.0 3.6 7.9 6.7 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KEY71453.1 - 1.6 8.5 7.6 0.71 9.6 0.8 2.5 2 0 0 2 2 2 0 BED zinc finger MRP-L47 PF06984.8 KEY71454.1 - 1.6e-25 88.8 0.2 2.6e-25 88.1 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.7 KEY71454.1 - 0.24 10.6 1.7 0.46 9.7 1.2 1.4 1 0 0 1 1 1 0 Clc-like GDI PF00996.13 KEY71455.1 - 1.2e-177 590.6 0.0 1.5e-177 590.3 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 KEY71455.1 - 0.059 13.3 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NOGCT PF08155.6 KEY71456.1 - 2.1e-28 97.7 2.1 2.1e-28 97.7 1.4 1.8 2 0 0 2 2 2 1 NOGCT (NUC087) domain NOG1 PF06858.9 KEY71456.1 - 5.1e-27 93.5 1.0 1.3e-26 92.2 0.7 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 KEY71456.1 - 5.1e-15 55.4 0.0 1.2e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEY71456.1 - 7.9e-08 31.7 0.0 1.6e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KEY71456.1 - 2.3e-05 24.8 0.3 0.0013 19.2 0.0 3.1 3 0 0 3 3 3 1 Miro-like protein Dynamin_N PF00350.18 KEY71456.1 - 0.014 15.2 1.4 5 6.9 0.0 3.3 2 1 1 3 3 3 0 Dynamin family AAA_16 PF13191.1 KEY71456.1 - 0.07 13.1 4.4 1.9 8.4 0.0 3.7 3 1 0 4 4 4 0 AAA ATPase domain MobB PF03205.9 KEY71456.1 - 0.087 12.5 0.1 0.57 9.8 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Asp_protease PF09668.5 KEY71457.1 - 1.1e-59 199.3 0.1 1.7e-59 198.8 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 KEY71457.1 - 5.9e-12 45.9 0.1 1.4e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KEY71457.1 - 9.2e-08 31.8 0.0 2.8e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBA PF00627.26 KEY71457.1 - 1e-07 31.5 0.1 2.1e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.18 KEY71457.1 - 3.5e-07 29.5 0.0 7.5e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family RVP_2 PF08284.6 KEY71457.1 - 4.4e-07 29.9 0.0 7.1e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 KEY71457.1 - 3.3e-06 26.9 0.0 1e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease EssA PF10661.4 KEY71457.1 - 0.015 14.9 1.6 0.024 14.3 1.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA UN_NPL4 PF11543.3 KEY71457.1 - 0.017 15.3 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 UBA_4 PF14555.1 KEY71457.1 - 0.062 12.8 0.1 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain CUE PF02845.11 KEY71457.1 - 0.12 11.8 0.6 11 5.5 0.0 2.6 2 0 0 2 2 2 0 CUE domain Methyltransf_8 PF05148.10 KEY71458.1 - 8.7e-60 202.0 0.0 1.4e-57 194.8 0.0 2.8 2 1 1 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 KEY71458.1 - 2.6e-06 27.8 0.0 6.4e-05 23.3 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KEY71458.1 - 0.088 12.1 0.0 3.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain NARP1 PF12569.3 KEY71458.1 - 8.1 5.0 11.6 15 4.2 8.1 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Fungal_trans_2 PF11951.3 KEY71459.1 - 2.2e-18 66.0 0.0 4.6e-12 45.2 0.6 2.6 2 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY71459.1 - 4.6e-08 32.8 11.6 8.6e-08 31.9 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY71459.1 - 1.1e-05 24.4 2.0 0.0042 16.0 0.2 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Proteasome PF00227.21 KEY71460.1 - 6.7e-56 188.5 0.1 8.6e-56 188.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEY71460.1 - 2.4e-11 42.7 0.0 5.5e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 KEY71460.1 - 0.011 15.4 0.2 0.26 10.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) Spc97_Spc98 PF04130.8 KEY71461.1 - 1.4e-129 432.8 0.2 2.1e-129 432.3 0.1 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family SNF2_N PF00176.18 KEY71462.1 - 1.5e-68 230.8 0.0 2e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEY71462.1 - 5.1e-10 39.0 0.0 1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 KEY71462.1 - 8.2e-06 25.4 2.3 1.8e-05 24.3 1.6 1.6 1 1 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.24 KEY71462.1 - 6e-05 22.5 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.1 KEY71462.1 - 0.0004 20.1 0.8 0.00096 18.9 0.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEY71462.1 - 0.0022 17.9 1.3 0.0022 17.9 0.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEY71462.1 - 0.0073 15.9 4.7 0.023 14.3 3.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEY71462.1 - 0.015 14.9 4.4 0.05 13.2 3.1 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 KEY71462.1 - 0.63 9.6 5.8 4.4 6.9 4.0 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 KEY71462.1 - 4.4 7.2 5.6 0.68 9.8 1.0 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Peptidase_C53 PF05550.6 KEY71463.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Pestivirus Npro endopeptidase C53 HSP70 PF00012.15 KEY71465.1 - 4.2e-266 883.6 14.6 4.8e-266 883.4 10.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KEY71465.1 - 7.7e-14 51.0 4.3 7.6e-12 44.4 0.9 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 KEY71465.1 - 0.00014 21.5 0.1 0.00044 19.9 0.1 1.9 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KEY71465.1 - 0.015 15.1 9.2 16 5.3 3.6 4.5 2 1 0 2 2 2 0 Cell division protein FtsA DUF4363 PF14276.1 KEY71465.1 - 0.87 9.2 3.6 2.1 8.0 2.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) WD40 PF00400.27 KEY71466.1 - 2.2e-27 93.8 13.2 3.3e-10 39.4 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF3639 PF12341.3 KEY71466.1 - 0.36 10.8 0.0 0.36 10.8 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3639) 2OG-FeII_Oxy_2 PF13532.1 KEY71467.1 - 6.1e-34 117.5 0.0 8e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 KEY71467.1 - 2.2e-09 37.0 6.4 4e-09 36.2 4.4 1.4 1 0 0 1 1 1 1 GRF zinc finger CUE PF02845.11 KEY71467.1 - 0.0059 16.0 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 CUE domain 2OG-FeII_Oxy PF03171.15 KEY71467.1 - 0.008 16.4 0.0 0.028 14.7 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UTRA PF07702.8 KEY71467.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 UTRA domain DUF2415 PF10313.4 KEY71468.1 - 1.7e-12 46.7 0.0 4e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 KEY71468.1 - 0.029 14.2 0.1 2.8 7.9 0.1 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat DAO PF01266.19 KEY71469.1 - 5.4e-54 183.4 7.9 6.6e-54 183.1 5.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY71469.1 - 9.2e-06 25.6 1.1 2.5e-05 24.2 0.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEY71469.1 - 1.6e-05 25.0 0.0 0.00082 19.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEY71469.1 - 2.6e-05 23.5 3.1 0.00027 20.1 2.2 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEY71469.1 - 0.01 15.7 0.2 0.02 14.7 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEY71469.1 - 0.023 13.7 0.4 0.042 12.9 0.2 1.5 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 KEY71469.1 - 0.033 14.6 0.2 0.073 13.4 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEY71469.1 - 0.043 12.6 0.4 0.059 12.2 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 KEY71469.1 - 0.074 12.1 0.2 0.074 12.1 0.1 2.0 3 0 0 3 3 3 0 Thi4 family priB_priC PF07445.7 KEY71470.1 - 0.021 14.3 1.2 0.021 14.3 0.8 1.5 2 0 0 2 2 2 0 Primosomal replication protein priB and priC DUF1465 PF07323.7 KEY71470.1 - 0.029 13.9 0.8 0.07 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) DASH_Spc34 PF08657.5 KEY71470.1 - 0.041 13.5 1.3 0.86 9.2 0.5 2.1 2 0 0 2 2 2 0 DASH complex subunit Spc34 SlyX PF04102.7 KEY71470.1 - 0.049 14.0 5.0 2.2 8.7 1.0 2.6 2 0 0 2 2 2 0 SlyX Leu_zip PF15294.1 KEY71470.1 - 0.049 12.7 1.2 0.066 12.3 0.0 1.7 2 0 0 2 2 2 0 Leucine zipper Pox_A_type_inc PF04508.7 KEY71470.1 - 0.1 12.4 1.7 0.22 11.3 0.1 2.4 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat DivIC PF04977.10 KEY71470.1 - 0.17 11.3 3.6 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Septum formation initiator ARS2 PF04959.8 KEY71470.1 - 0.32 11.1 2.7 0.25 11.4 0.3 1.9 1 1 1 2 2 2 0 Arsenite-resistance protein 2 DUF2046 PF09755.4 KEY71470.1 - 0.32 9.8 3.2 0.17 10.7 0.5 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Mitofilin PF09731.4 KEY71470.1 - 0.4 9.2 3.9 0.68 8.5 2.7 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Fib_alpha PF08702.5 KEY71470.1 - 0.57 10.2 2.3 23 5.0 0.0 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Nsp1_C PF05064.8 KEY71470.1 - 3.6 7.2 6.1 0.72 9.5 1.3 1.8 2 0 0 2 2 2 0 Nsp1-like C-terminal region GSDH PF07995.6 KEY71472.1 - 0.0012 18.0 0.1 0.0036 16.4 0.1 1.9 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase SBBP PF06739.6 KEY71472.1 - 0.032 14.0 0.0 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Beta-propeller repeat PBP1_TM PF14812.1 KEY71473.1 - 0.044 14.0 2.3 0.044 14.0 1.6 2.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 KEY71473.1 - 0.17 11.3 0.7 0.26 10.7 0.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin Syndecan PF01034.15 KEY71473.1 - 0.28 10.8 1.9 0.48 10.1 1.3 1.3 1 0 0 1 1 1 0 Syndecan domain MIP-T3 PF10243.4 KEY71473.1 - 0.44 8.9 5.8 0.77 8.1 4.0 1.2 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF4307 PF14155.1 KEY71473.1 - 1.4 8.7 3.9 6.3 6.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) Fungal_trans PF04082.13 KEY71474.1 - 4.1e-33 114.3 0.0 5.6e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY71474.1 - 3.5e-09 36.4 9.3 5.6e-09 35.7 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RskA PF10099.4 KEY71475.1 - 0.0064 16.2 0.7 0.0082 15.8 0.5 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Utp13 PF08625.6 KEY71475.1 - 0.012 15.2 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Cpl-7 PF08230.6 KEY71475.1 - 0.08 12.6 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Cpl-7 lysozyme C-terminal domain MFS_1 PF07690.11 KEY71476.1 - 1.4e-42 145.7 4.0 1.4e-42 145.7 2.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY71476.1 - 5.2e-11 41.7 2.6 5.2e-11 41.7 1.8 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KEY71476.1 - 1.8e-05 23.3 16.0 0.00017 20.1 1.7 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein Nuc_H_symport PF03825.11 KEY71476.1 - 0.00053 18.8 0.3 0.00053 18.8 0.2 1.8 2 0 0 2 2 2 1 Nucleoside H+ symporter DUF1014 PF06244.7 KEY71477.1 - 5.6e-21 75.0 7.9 1.5e-20 73.6 4.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1014) UQ_con PF00179.21 KEY71477.1 - 4.5e-10 39.1 0.1 1.3e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PfkB PF00294.19 KEY71478.1 - 6.1e-54 183.1 0.2 7.7e-54 182.8 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase p450 PF00067.17 KEY71479.1 - 4.4e-49 167.2 0.0 5.6e-32 110.8 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 RibD_C PF01872.12 KEY71480.1 - 6.1e-33 114.1 0.0 8.7e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain CM_2 PF01817.16 KEY71481.1 - 6.2e-08 32.6 0.5 0.00022 21.2 0.0 3.1 2 1 0 2 2 2 2 Chorismate mutase type II DEAD PF00270.24 KEY71482.1 - 1.9e-41 141.3 0.1 3.9e-41 140.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY71482.1 - 7.7e-22 76.9 0.6 1.3e-20 73.0 0.5 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DsrH PF04077.7 KEY71482.1 - 0.013 15.1 0.2 0.84 9.3 0.0 2.5 2 0 0 2 2 2 0 DsrH like protein ResIII PF04851.10 KEY71482.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit INCENP_ARK-bind PF03941.10 KEY71483.1 - 8.9e-20 70.2 0.3 8.9e-20 70.2 0.2 2.0 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region SMC_N PF02463.14 KEY71484.1 - 1.9e-70 236.5 2.3 4.2e-69 232.1 1.6 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KEY71484.1 - 3.5e-21 75.3 0.3 3.5e-21 75.3 0.2 3.0 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KEY71484.1 - 1.3e-10 41.7 9.3 3e-05 24.1 0.4 3.3 3 2 0 3 3 3 2 AAA domain Reo_sigmaC PF04582.7 KEY71484.1 - 4.2e-06 26.1 34.5 0.0049 16.0 1.0 6.6 3 2 5 8 8 8 3 Reovirus sigma C capsid protein AAA_29 PF13555.1 KEY71484.1 - 0.00086 18.7 0.0 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KEY71484.1 - 3.8 7.8 24.3 1.3 9.2 0.0 5.3 3 2 0 3 3 3 0 ABC transporter DUF2316 PF10078.4 KEY71484.1 - 4.7 7.2 11.2 0.34 10.9 0.6 4.3 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2316) MOSC PF03473.12 KEY71485.1 - 2.1e-15 56.3 0.0 3.6e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 KEY71485.1 - 1.9e-13 50.2 0.0 5.3e-13 48.7 0.0 1.7 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain Fungal_trans_2 PF11951.3 KEY71487.1 - 2.9e-11 42.5 1.5 2.4e-10 39.5 1.0 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY71487.1 - 1.4e-07 31.2 9.7 2.4e-07 30.5 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mob1_phocein PF03637.12 KEY71488.1 - 3.5e-26 91.9 0.3 5.3e-26 91.3 0.2 1.2 1 0 0 1 1 1 1 Mob1/phocein family cobW PF02492.14 KEY71489.1 - 4.1e-31 107.7 0.3 1.1e-30 106.4 0.2 1.6 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KEY71489.1 - 0.00051 19.6 0.0 0.00092 18.8 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain ArgK PF03308.11 KEY71489.1 - 0.001 17.9 1.1 0.28 9.9 0.1 2.8 3 0 0 3 3 3 2 ArgK protein GTP_EFTU PF00009.22 KEY71489.1 - 0.0016 17.9 0.1 0.49 9.7 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KEY71489.1 - 0.006 16.7 0.2 0.15 12.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KEY71489.1 - 0.007 16.7 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 KEY71489.1 - 0.0074 16.7 0.1 0.11 12.9 0.0 2.7 3 0 0 3 3 3 1 Miro-like protein AAA_19 PF13245.1 KEY71489.1 - 0.0098 15.6 0.5 0.021 14.5 0.1 1.8 2 0 0 2 2 1 1 Part of AAA domain ABC_tran PF00005.22 KEY71489.1 - 0.017 15.3 0.2 0.067 13.4 0.1 1.9 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.18 KEY71489.1 - 0.021 14.7 2.3 0.12 12.3 0.5 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.1 KEY71489.1 - 0.022 14.3 1.1 0.64 9.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KEY71489.1 - 0.026 14.0 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.4 KEY71489.1 - 0.031 13.2 0.3 0.36 9.7 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATP_bind_1 PF03029.12 KEY71489.1 - 0.032 13.7 1.0 1.8 8.0 0.7 2.8 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 KEY71489.1 - 0.054 12.6 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 KEY71489.1 - 0.084 12.5 0.2 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KEY71489.1 - 0.094 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 KEY71489.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 KEY71489.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Septin PF00735.13 KEY71489.1 - 0.12 11.3 0.1 7.9 5.4 0.0 2.1 2 0 0 2 2 2 0 Septin NOT2_3_5 PF04153.13 KEY71490.1 - 4.2e-33 114.0 1.5 6.4e-33 113.4 1.0 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family CUE PF02845.11 KEY71491.1 - 4.7e-11 41.9 0.0 7.3e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 CUE domain Metal_resist PF13801.1 KEY71491.1 - 0.28 11.1 9.5 0.53 10.2 0.6 2.2 2 0 0 2 2 2 0 Heavy-metal resistance Reticulon PF02453.12 KEY71492.1 - 9.1e-39 132.7 3.0 1.4e-38 132.2 2.1 1.2 1 0 0 1 1 1 1 Reticulon Choline_transpo PF04515.7 KEY71492.1 - 0.0094 14.7 0.7 0.015 14.0 0.5 1.3 1 0 0 1 1 1 1 Plasma-membrane choline transporter Guanylate_kin PF00625.16 KEY71492.1 - 0.067 12.6 0.3 4.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase Folliculin PF11704.3 KEY71492.1 - 0.15 11.6 0.6 0.32 10.5 0.1 1.6 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport RabGAP-TBC PF00566.13 KEY71493.1 - 1.9e-47 161.5 0.0 6.3e-47 159.8 0.0 2.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Prp19 PF08606.6 KEY71493.1 - 0.15 11.7 8.7 0.067 12.9 1.0 3.3 3 0 0 3 3 3 0 Prp19/Pso4-like DUF1664 PF07889.7 KEY71493.1 - 0.89 9.3 9.0 0.19 11.5 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.8 KEY71493.1 - 1.6 8.0 6.7 6 6.2 4.7 1.9 1 0 0 1 1 1 0 fzo-like conserved region Laminin_II PF06009.7 KEY71493.1 - 9.9 5.9 17.1 0.049 13.3 2.7 3.1 3 0 0 3 3 3 0 Laminin Domain II DUF4330 PF14221.1 KEY71494.1 - 0.87 9.4 2.0 3.9 7.3 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) TAP42 PF04177.7 KEY71496.1 - 8.4e-85 284.7 0.0 9.5e-85 284.5 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family DNA_topoisoIV PF00521.15 KEY71497.1 - 1.3e-120 403.1 0.1 3.8e-120 401.6 0.0 1.9 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KEY71497.1 - 7.8e-32 109.8 1.0 2.2e-31 108.4 0.7 1.8 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 KEY71497.1 - 4e-14 52.3 0.1 2.5e-13 49.8 0.0 2.4 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 KEY71497.1 - 4.1e-09 36.1 0.0 1.2e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_11 PF13414.1 KEY71499.1 - 9.3e-08 31.6 8.0 2.3e-07 30.3 0.4 3.0 1 1 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 KEY71499.1 - 0.0001 21.9 13.2 0.1 12.5 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 KEY71499.1 - 0.0033 17.7 1.3 0.0033 17.7 0.9 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEY71499.1 - 0.0046 16.5 8.0 1.5 8.5 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat AFOR_C PF01314.13 KEY71499.1 - 0.14 10.8 0.8 0.21 10.2 0.5 1.2 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 MFS_1 PF07690.11 KEY71500.1 - 1.5e-33 116.0 28.6 3.9e-26 91.6 4.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY71500.1 - 1.9e-11 43.1 1.9 1.9e-11 43.1 1.3 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 KEY71500.1 - 8.2e-05 21.1 1.5 8.2e-05 21.1 1.0 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 KEY71500.1 - 0.027 12.5 1.5 0.051 11.6 1.1 1.4 1 0 0 1 1 1 0 Transmembrane secretion effector HIT PF01230.18 KEY71501.1 - 2.1e-18 66.6 0.1 3.2e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KEY71501.1 - 0.00091 19.4 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding MFS_1 PF07690.11 KEY71502.1 - 1.4e-25 89.7 33.7 9.8e-21 73.8 10.3 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF1751 PF08551.5 KEY71502.1 - 0.0017 18.6 0.2 0.26 11.6 0.1 2.8 2 0 0 2 2 2 2 Eukaryotic integral membrane protein (DUF1751) Myb_Cef PF11831.3 KEY71503.1 - 6.8e-62 208.7 6.3 6.8e-62 208.7 4.4 3.6 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 KEY71503.1 - 7.7e-21 73.8 3.7 1.5e-09 37.7 0.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEY71503.1 - 1.2e-19 70.1 5.0 1.8e-14 53.5 2.2 3.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain MFS_1 PF07690.11 KEY71504.1 - 3.5e-38 131.2 64.4 1.1e-36 126.3 27.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KEY71504.1 - 1.7e-07 29.8 16.7 6.4e-05 21.3 0.4 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Hexokinase_1 PF00349.16 KEY71505.1 - 1.1e-22 80.3 0.0 8e-22 77.5 0.0 2.0 1 1 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 KEY71505.1 - 2.6e-21 75.9 0.0 3.7e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase GILT PF03227.11 KEY71506.1 - 1.1e-14 54.2 0.0 1.6e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DcpS_C PF11969.3 KEY71507.1 - 6.7e-31 106.9 0.1 1e-30 106.3 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 KEY71507.1 - 1.2e-22 80.3 0.0 1.5e-19 70.4 0.0 2.4 1 1 1 2 2 2 2 Scavenger mRNA decapping enzyme (DcpS) N-terminal DUF385 PF04075.9 KEY71507.1 - 0.058 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF385) SH3_9 PF14604.1 KEY71508.1 - 9.1e-07 28.3 0.1 1.9e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KEY71508.1 - 0.00026 20.2 0.3 0.00069 18.9 0.0 1.8 2 0 0 2 2 2 1 SH3 domain Glycophorin_A PF01102.13 KEY71508.1 - 0.0062 16.2 0.0 0.049 13.4 0.0 2.4 2 0 0 2 2 2 1 Glycophorin A Adeno_E3_CR2 PF02439.10 KEY71508.1 - 0.01 15.3 0.5 0.023 14.2 0.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1183 PF06682.7 KEY71508.1 - 0.039 13.5 10.4 0.11 12.1 7.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) Podoplanin PF05808.6 KEY71508.1 - 0.041 13.4 0.0 0.095 12.2 0.0 1.6 1 0 0 1 1 1 0 Podoplanin DUF4448 PF14610.1 KEY71508.1 - 0.07 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF2668 PF10873.3 KEY71508.1 - 0.083 13.0 0.1 0.083 13.0 0.1 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2668) Mid2 PF04478.7 KEY71508.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.5 KEY71508.1 - 0.51 9.6 4.9 1.1 8.6 3.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3112 PF11309.3 KEY71509.1 - 7.5e-37 126.5 7.3 7.5e-37 126.5 5.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) DUF2985 PF11204.3 KEY71509.1 - 0.41 10.4 3.3 0.32 10.7 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) Metallophos PF00149.23 KEY71510.1 - 3.2e-44 150.7 1.3 4.1e-44 150.3 0.9 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Vps51 PF08700.6 KEY71511.1 - 4.1e-16 58.5 1.8 4.1e-16 58.5 1.3 2.0 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 KEY71511.1 - 0.005 16.7 0.9 0.23 11.3 0.0 2.4 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2383 PF09537.5 KEY71511.1 - 0.029 14.5 4.2 0.095 12.9 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Laminin_B PF00052.13 KEY71511.1 - 0.092 12.3 0.1 0.27 10.8 0.1 1.8 1 0 0 1 1 1 0 Laminin B (Domain IV) Atg14 PF10186.4 KEY71511.1 - 4.3 6.1 11.5 0.21 10.5 1.4 2.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 MAS20 PF02064.10 KEY71512.1 - 6.3e-16 58.3 0.3 1.5e-15 57.1 0.2 1.5 1 1 0 1 1 1 1 MAS20 protein import receptor Radical_SAM PF04055.16 KEY71513.1 - 1.3e-25 90.4 0.1 2.7e-25 89.4 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 KEY71513.1 - 7.4e-24 83.6 0.0 1.6e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 KEY71513.1 - 7.4e-10 38.9 0.4 3.7e-07 30.2 0.2 3.5 2 1 0 2 2 2 1 Flavodoxin CDO_I PF05995.7 KEY71514.1 - 1.5e-37 128.4 0.0 2e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 KEY71514.1 - 0.0091 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) SNF2_N PF00176.18 KEY71515.1 - 2.7e-71 239.8 0.0 3.8e-71 239.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KEY71515.1 - 3.9e-13 49.2 0.0 9.4e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain zf-RING_2 PF13639.1 KEY71515.1 - 1.7e-10 40.5 9.3 1.7e-10 40.5 6.4 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KEY71515.1 - 2.2e-10 40.0 10.8 2.4e-09 36.6 6.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEY71515.1 - 2.1e-09 37.2 14.3 7.3e-09 35.5 8.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 KEY71515.1 - 1.9e-08 34.0 0.0 1.9e-07 30.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 KEY71515.1 - 8.9e-08 31.6 12.6 8.9e-08 31.6 8.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY71515.1 - 1.8e-07 30.7 10.3 1.8e-07 30.7 7.1 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 KEY71515.1 - 0.00072 19.6 8.7 0.0025 17.8 6.0 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 KEY71515.1 - 0.00076 19.3 9.9 0.0017 18.1 6.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KEY71515.1 - 0.0014 18.4 3.5 0.0014 18.4 2.4 2.5 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KEY71515.1 - 0.003 17.3 3.2 0.0065 16.2 2.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KEY71515.1 - 0.021 14.5 11.9 0.016 14.8 6.2 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 KEY71515.1 - 0.05 13.2 7.9 0.12 11.9 5.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain NCA2 PF08637.5 KEY71516.1 - 1.5e-84 283.3 0.0 2.4e-84 282.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 FA_hydroxylase PF04116.8 KEY71517.1 - 1.3e-16 60.9 15.0 1.3e-16 60.9 10.4 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Pterin_4a PF01329.14 KEY71518.1 - 1e-28 98.9 0.1 1.8e-28 98.1 0.1 1.4 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Trypsin PF00089.21 KEY71521.1 - 1.2e-11 44.6 0.4 2.1e-11 43.8 0.3 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 KEY71521.1 - 1.8e-10 40.8 0.0 2.9e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Transp_cyt_pur PF02133.10 KEY71522.1 - 5.6e-28 97.6 33.7 1.3e-27 96.4 23.4 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidohydro_1 PF01979.15 KEY71523.1 - 3.6e-40 138.6 0.2 4.4e-40 138.3 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KEY71523.1 - 1.2e-15 58.3 0.3 6.3e-15 55.9 0.2 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KEY71523.1 - 8.6e-15 54.3 0.0 3.1e-14 52.5 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KEY71523.1 - 1.1e-09 38.0 0.0 1.1e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Fungal_trans_2 PF11951.3 KEY71524.1 - 1.4e-47 162.1 0.1 1.8e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY71524.1 - 1.4e-07 31.2 6.9 3e-07 30.2 4.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 KEY71525.1 - 8.7e-22 77.5 0.0 1.2e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY71525.1 - 2.5e-15 56.9 0.0 5.5e-15 55.8 0.0 1.6 1 1 1 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 KEY71525.1 - 2e-05 23.7 0.1 5.6e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase Epimerase PF01370.16 KEY71525.1 - 0.0054 16.1 0.0 0.08 12.3 0.0 2.4 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KEY71525.1 - 0.018 15.1 0.0 0.07 13.2 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 KEY71525.1 - 0.063 13.5 0.1 0.62 10.3 0.0 2.4 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain NUDIX PF00293.23 KEY71526.1 - 2e-14 53.3 0.1 5.8e-13 48.6 0.0 2.1 2 0 0 2 2 2 2 NUDIX domain FAD_binding_4 PF01565.18 KEY71527.1 - 2.5e-22 78.8 0.3 5.6e-22 77.7 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain p450 PF00067.17 KEY71528.1 - 4.4e-16 58.4 0.0 7.7e-16 57.6 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 Sulfotransfer_3 PF13469.1 KEY71528.1 - 6.1e-05 24.0 1.6 0.0006 20.7 1.2 2.5 1 1 0 1 1 1 1 Sulfotransferase family DUF4328 PF14219.1 KEY71529.1 - 0.017 14.3 0.3 0.017 14.3 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) Cellulase PF00150.13 KEY71530.1 - 1.9e-18 66.6 0.9 2.5e-18 66.2 0.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KEY71530.1 - 1.9e-10 40.2 4.6 5.7e-10 38.6 3.2 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.12 KEY71530.1 - 0.00041 19.3 0.0 0.00076 18.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase-like PF12876.2 KEY71530.1 - 0.0026 18.1 0.0 0.0068 16.8 0.0 1.8 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 KEY71530.1 - 0.0055 15.8 0.9 0.016 14.3 0.1 1.9 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_10 PF00331.15 KEY71530.1 - 0.014 14.4 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Glyoxalase_2 PF12681.2 KEY71530.1 - 0.061 13.9 0.0 0.9 10.1 0.0 2.6 1 1 1 2 2 2 0 Glyoxalase-like domain Amidohydro_2 PF04909.9 KEY71531.1 - 1.9e-44 152.2 0.0 2.1e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Glyco_hydro_61 PF03443.9 KEY71532.1 - 1.2e-66 224.6 0.0 1.3e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 adh_short PF00106.20 KEY71533.1 - 1.1e-13 51.4 0.1 2.2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY71533.1 - 3.2e-08 33.4 0.1 7.1e-08 32.3 0.1 1.5 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 KEY71533.1 - 0.035 13.8 1.0 0.054 13.2 0.1 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 KEY71533.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Zn_clus PF00172.13 KEY71534.1 - 4.1e-09 36.2 6.9 8.5e-09 35.1 4.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEY71535.1 - 2.4e-17 62.6 4.5 2.3e-09 36.3 0.2 2.1 1 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY71535.1 - 6.8e-05 22.6 8.3 0.00013 21.8 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.16 KEY71536.1 - 1.6e-92 310.0 0.0 2e-92 309.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aldedh PF00171.17 KEY71537.1 - 4.1e-132 440.8 0.0 4.6e-132 440.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KEY71537.1 - 0.094 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Aldedh PF00171.17 KEY71538.1 - 2.4e-181 603.0 1.3 2.7e-181 602.9 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KEY71538.1 - 0.023 13.4 0.0 0.044 12.5 0.0 1.4 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Zn_clus PF00172.13 KEY71539.1 - 4.7e-06 26.4 8.9 8.6e-06 25.5 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEY71540.1 - 4.6e-18 64.9 2.5 6.5e-18 64.4 1.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.19 KEY71541.1 - 1.8e-44 152.1 1.0 2.1e-44 151.9 0.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KEY71541.1 - 0.00015 20.9 0.3 0.00025 20.2 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 KEY71541.1 - 0.00051 20.1 0.1 0.51 10.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY71541.1 - 0.00082 18.3 0.1 0.0014 17.6 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEY71541.1 - 0.001 18.9 1.7 0.0029 17.5 0.7 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY71541.1 - 0.0024 17.8 1.2 0.0024 17.8 0.9 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.10 KEY71541.1 - 0.025 12.7 0.0 0.035 12.2 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) FAD_oxidored PF12831.2 KEY71541.1 - 0.063 12.3 2.9 0.093 11.7 2.0 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEY71541.1 - 0.084 11.7 6.4 0.52 9.0 4.5 2.0 1 1 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KEY71541.1 - 0.28 9.6 1.3 13 4.1 0.7 2.2 2 0 0 2 2 2 0 HI0933-like protein Amidase PF01425.16 KEY71542.1 - 8.3e-79 265.4 0.0 1e-78 265.1 0.0 1.0 1 0 0 1 1 1 1 Amidase AA_permease_2 PF13520.1 KEY71543.1 - 1.1e-26 93.4 39.6 4.7e-22 78.1 14.0 2.1 1 1 1 2 2 2 2 Amino acid permease ADH_zinc_N PF00107.21 KEY71544.1 - 8.2e-09 35.0 0.0 1.5e-08 34.2 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase InvH PF04741.7 KEY71546.1 - 0.1 12.4 0.2 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 InvH outer membrane lipoprotein SNF2_N PF00176.18 KEY71548.1 - 1e-05 24.4 0.0 0.00028 19.7 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain HET PF06985.6 KEY71550.1 - 1.3e-10 41.5 3.2 2.6e-08 34.1 0.5 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Mut7-C PF01927.11 KEY71550.1 - 3.2 7.7 4.8 45 4.0 0.1 3.0 2 1 1 3 3 3 0 Mut7-C RNAse domain Ank_2 PF12796.2 KEY71551.1 - 1.9e-110 361.4 10.4 6.4e-19 68.0 0.2 7.3 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KEY71551.1 - 2.3e-103 333.2 0.6 6.6e-07 28.8 0.0 15.8 16 0 0 16 16 16 15 Ankyrin repeat Ank_5 PF13857.1 KEY71551.1 - 2.4e-88 288.1 7.9 5.6e-10 39.1 0.0 14.0 3 3 12 15 15 15 14 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEY71551.1 - 3e-75 247.3 1.6 1.7e-10 41.0 0.0 10.4 6 1 4 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY71551.1 - 3.2e-68 218.7 0.0 0.00079 19.4 0.0 15.5 15 0 0 15 15 15 14 Ankyrin repeat DUF1843 PF08898.5 KEY71551.1 - 5.1e-06 26.4 25.5 0.35 10.9 0.3 7.2 8 0 0 8 8 8 4 Domain of unknown function (DUF1843) DUF2520 PF10728.4 KEY71551.1 - 0.017 14.5 6.6 1.3 8.4 2.2 4.6 2 1 3 5 5 5 0 Domain of unknown function (DUF2520) Phage_T7_Capsid PF05396.6 KEY71551.1 - 0.028 14.5 1.9 41 4.3 0.1 3.9 1 1 2 3 3 3 0 Phage T7 capsid assembly protein Shigella_OspC PF06128.6 KEY71551.1 - 0.069 12.6 7.0 28 4.0 0.0 5.9 3 2 4 7 7 7 0 Shigella flexneri OspC protein Nuc_rec_co-act PF08815.5 KEY71552.1 - 0.03 13.8 0.1 0.067 12.7 0.0 1.6 1 0 0 1 1 1 0 Nuclear receptor coactivator Adeno_E3_CR2 PF02439.10 KEY71554.1 - 0.26 10.8 1.8 0.26 10.8 1.3 1.1 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Nnf1 PF03980.9 KEY71555.1 - 4.5e-29 100.6 1.1 5.3e-28 97.1 0.2 2.1 2 0 0 2 2 2 1 Nnf1 Auts2 PF15336.1 KEY71555.1 - 0.0045 17.0 0.6 0.0061 16.6 0.4 1.1 1 0 0 1 1 1 1 Autism susceptibility gene 2 protein DUF1908 PF08926.6 KEY71555.1 - 0.012 14.3 0.0 0.024 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) RmuC PF02646.11 KEY71555.1 - 0.064 12.0 0.7 0.092 11.5 0.3 1.4 1 1 0 1 1 1 0 RmuC family FliJ PF02050.11 KEY71555.1 - 0.16 12.0 8.0 0.044 13.8 1.4 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein FUSC PF04632.7 KEY71555.1 - 1.8 6.8 13.7 2.4 6.4 9.4 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family DivIC PF04977.10 KEY71555.1 - 8.6 5.9 8.1 1.3 8.5 0.4 2.6 2 1 1 3 3 3 0 Septum formation initiator PH PF00169.24 KEY71556.1 - 4.2e-05 23.7 0.0 7.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 KEY71556.1 - 8.4e-05 22.7 0.0 0.00014 22.0 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Chromo PF00385.19 KEY71557.1 - 0.0044 16.6 0.3 0.65 9.7 0.0 2.9 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain G-alpha PF00503.15 KEY71559.1 - 6.8e-51 173.1 0.0 8.4e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KEY71559.1 - 0.00012 21.3 0.0 0.0046 16.2 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_33 PF13671.1 KEY71559.1 - 0.0012 18.7 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEY71559.1 - 0.0013 18.8 0.0 0.0031 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KEY71559.1 - 0.0019 17.1 0.0 0.0028 16.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KEY71559.1 - 0.0045 17.0 0.0 0.0064 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 KEY71559.1 - 0.0046 17.2 0.0 0.0082 16.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA PF00004.24 KEY71559.1 - 0.0053 16.9 0.0 0.023 14.8 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEY71559.1 - 0.0062 17.3 0.1 0.014 16.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEY71559.1 - 0.026 14.8 0.2 0.095 13.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain DAP3 PF10236.4 KEY71559.1 - 0.031 13.2 0.0 0.082 11.8 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_28 PF13521.1 KEY71559.1 - 0.047 13.6 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KEY71559.1 - 0.058 12.9 0.0 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEY71559.1 - 0.08 13.1 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.10 KEY71559.1 - 0.092 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 KEY71559.1 - 0.11 11.8 0.1 0.36 10.2 0.1 1.9 2 1 0 2 2 2 0 AAA-like domain MCM PF00493.18 KEY71559.1 - 0.14 10.9 0.0 0.27 9.9 0.0 1.4 1 1 0 1 1 1 0 MCM2/3/5 family WD40 PF00400.27 KEY71560.1 - 3.4e-245 784.4 45.6 2.5e-14 52.4 0.0 22.4 21 1 0 21 21 21 21 WD domain, G-beta repeat Nup160 PF11715.3 KEY71560.1 - 3.2e-55 187.2 66.4 0.00039 18.6 0.1 19.0 1 1 15 18 18 18 17 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KEY71560.1 - 1.1e-13 50.7 11.1 0.3 9.7 0.0 10.4 2 1 7 10 10 10 5 Nup133 N terminal like BLUF PF04940.7 KEY71560.1 - 5.9e-12 45.1 11.0 3.7 7.3 0.0 13.2 9 4 4 14 14 14 1 Sensors of blue-light using FAD Cytochrom_D1 PF02239.11 KEY71560.1 - 7.4e-10 37.6 0.3 0.28 9.4 0.0 6.2 2 2 4 7 7 7 4 Cytochrome D1 heme domain NACHT PF05729.7 KEY71560.1 - 8.7e-10 38.4 0.0 1.9e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEY71560.1 - 6e-07 29.6 0.0 2.8e-06 27.4 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain DUF4585 PF15232.1 KEY71560.1 - 3.9e-06 26.6 0.0 50 3.8 0.0 9.6 12 1 1 13 13 13 0 Domain of unknown function (DUF4585) DUF1652 PF07865.6 KEY71560.1 - 5.1e-06 25.9 1.2 14 5.3 0.0 8.9 11 0 0 11 11 11 0 Protein of unknown function (DUF1652) NB-ARC PF00931.17 KEY71560.1 - 0.00026 19.9 0.0 0.00048 19.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain DUF3748 PF12566.3 KEY71560.1 - 0.00049 20.0 0.2 1.3e+02 2.4 0.0 7.6 8 2 3 11 11 9 0 Protein of unknown function (DUF3748) AAA_22 PF13401.1 KEY71560.1 - 0.0057 16.8 0.0 0.019 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.9 KEY71560.1 - 0.012 14.5 0.0 0.022 13.6 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase PSD5 PF07637.6 KEY71560.1 - 0.024 14.6 0.0 1.1e+02 2.9 0.0 5.8 7 0 0 7 7 6 0 Protein of unknown function (DUF1595) APS_kinase PF01583.15 KEY71560.1 - 0.049 13.2 0.1 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.24 KEY71560.1 - 0.05 13.8 0.1 0.28 11.3 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEY71560.1 - 0.083 12.6 0.0 0.35 10.6 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 KEY71560.1 - 0.12 12.6 0.1 0.32 11.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain CbiA PF01656.18 KEY71560.1 - 0.13 11.6 0.5 2 7.8 0.1 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.17 KEY71560.1 - 0.15 12.2 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.9 KEY71560.1 - 0.44 9.4 2.9 1.8 7.4 0.3 2.3 1 1 1 2 2 2 0 KAP family P-loop domain IU_nuc_hydro PF01156.14 KEY71561.1 - 4.9e-13 48.9 0.0 8.1e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase ADH_zinc_N PF00107.21 KEY71564.1 - 1.3e-08 34.4 0.0 2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY71564.1 - 3e-05 23.7 0.0 5.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Syndecan PF01034.15 KEY71565.1 - 0.0072 15.9 1.1 0.012 15.2 0.1 1.7 2 0 0 2 2 2 1 Syndecan domain DUF1191 PF06697.7 KEY71565.1 - 0.076 11.8 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF2268 PF10026.4 KEY71566.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) PGAP1 PF07819.8 KEY71567.1 - 9.4e-07 28.6 0.1 2.1e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KEY71567.1 - 2.6e-05 24.2 0.7 9e-05 22.4 0.5 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family CAF-1_p150 PF11600.3 KEY71567.1 - 0.0012 18.2 34.9 0.0012 18.2 24.2 1.7 2 0 0 2 2 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Abhydrolase_5 PF12695.2 KEY71567.1 - 0.0014 18.3 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KEY71567.1 - 0.0025 17.1 0.0 0.0066 15.7 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 KEY71567.1 - 0.053 13.0 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2305 PF10230.4 KEY71567.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) LCAT PF02450.10 KEY71567.1 - 0.18 10.7 0.0 0.18 10.7 0.0 1.6 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase SAPS PF04499.10 KEY71567.1 - 0.55 8.8 7.9 0.81 8.2 5.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SAGA-Tad1 PF12767.2 KEY71567.1 - 0.91 9.1 13.8 2 8.0 9.6 1.6 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Asp-B-Hydro_N PF05279.6 KEY71567.1 - 0.95 9.2 17.8 1.5 8.5 12.4 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DDRGK PF09756.4 KEY71567.1 - 1.2 8.5 34.1 2.2 7.6 23.7 1.4 1 0 0 1 1 1 0 DDRGK domain DDHD PF02862.12 KEY71567.1 - 1.6 8.4 12.9 0.48 10.1 6.9 1.6 2 0 0 2 2 2 0 DDHD domain HSP70 PF00012.15 KEY71567.1 - 2.2 6.1 11.7 3.1 5.6 8.1 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF342 PF03961.8 KEY71567.1 - 2.4 6.4 16.4 4.1 5.7 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1510 PF07423.6 KEY71567.1 - 4 6.7 19.5 7.1 5.9 13.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF853 PF05872.7 KEY71567.1 - 5.5 5.2 13.6 8.1 4.6 9.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Parvo_coat PF00740.13 KEY71567.1 - 5.6 5.8 9.9 8.2 5.2 6.8 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 HET PF06985.6 KEY71568.1 - 7.3e-07 29.4 0.0 1.8e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.23 KEY71569.1 - 1.5e-13 49.9 0.1 3.1e-06 25.8 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme DEAD PF00270.24 KEY71570.1 - 5.1e-45 152.9 0.0 4.9e-44 149.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY71570.1 - 8.5e-27 92.8 0.1 1.6e-26 91.9 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KEY71570.1 - 0.065 11.6 0.0 0.12 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) ResIII PF04851.10 KEY71570.1 - 0.072 12.9 0.0 0.18 11.6 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 KEY71570.1 - 0.19 10.7 0.0 0.33 9.9 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Proteasome PF00227.21 KEY71571.1 - 1.9e-38 131.6 0.0 2.3e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.27 KEY71572.1 - 8.8e-30 101.4 6.1 2.2e-08 33.6 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 KEY71572.1 - 0.0072 16.0 0.0 20 4.9 0.0 3.6 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 KEY71572.1 - 0.01 13.9 0.0 0.69 7.9 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Nha1_C PF08619.5 KEY71572.1 - 0.022 14.0 12.1 0.038 13.2 8.4 1.3 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Peptidase_C48 PF02902.14 KEY71573.1 - 3e-32 112.0 0.0 5.6e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SPC22 PF04573.7 KEY71574.1 - 1.3e-34 118.9 1.1 5.3e-25 87.6 0.1 2.1 2 0 0 2 2 2 2 Signal peptidase subunit XRN_N PF03159.13 KEY71575.1 - 3.2e-102 340.9 0.0 4.9e-102 340.3 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DsrD PF08679.6 KEY71575.1 - 0.045 13.7 2.6 1.8 8.6 0.1 2.9 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) DUF417 PF04224.7 KEY71575.1 - 0.14 11.5 0.0 0.59 9.4 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF417 WD40 PF00400.27 KEY71576.1 - 4.1e-40 134.2 0.2 4.4e-09 35.8 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KEY71576.1 - 4.4e-28 96.9 0.2 1e-27 95.7 0.1 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Abhydro_lipase PF04083.11 KEY71577.1 - 0.12 11.7 0.1 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region zf-RanBP PF00641.13 KEY71578.1 - 1.8e-18 65.3 13.4 5e-11 41.4 1.0 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 KEY71578.1 - 8.5e-09 34.9 0.0 2e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 KEY71578.1 - 2.3e-07 31.2 0.0 3.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 KEY71578.1 - 8.9e-06 25.5 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 KEY71578.1 - 2.7 7.8 11.1 0.77 9.6 0.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon Pmp3 PF01679.12 KEY71579.1 - 2.1e-20 72.1 9.2 2.6e-20 71.8 6.4 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator NapE PF06796.6 KEY71579.1 - 0.61 9.4 2.9 0.87 8.9 2.0 1.3 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE Pkinase PF00069.20 KEY71581.1 - 1.5e-68 230.7 0.0 2.5e-68 230.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY71581.1 - 2.5e-36 125.0 0.0 4.5e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY71581.1 - 1.1e-05 24.5 0.0 1.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEY71581.1 - 0.0013 17.8 0.1 0.0028 16.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Abhydrolase_6 PF12697.2 KEY71582.1 - 1.5e-10 41.3 0.0 3e-10 40.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY71582.1 - 3.5e-08 33.3 0.0 7.9e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY71582.1 - 3e-05 23.7 0.0 0.00017 21.3 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family NADH_B2 PF14813.1 KEY71583.1 - 0.16 11.6 0.0 0.44 10.2 0.0 1.8 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 DUF1764 PF08576.5 KEY71583.1 - 6.6 7.5 17.5 6.9 7.5 0.9 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) IF4E PF01652.13 KEY71584.1 - 1.1e-50 171.4 0.0 1.4e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E UCH PF00443.24 KEY71585.1 - 5.8e-28 97.7 0.0 8.3e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KEY71585.1 - 9.6e-12 44.8 0.1 9.6e-12 44.8 0.1 1.6 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KEY71585.1 - 6.3e-05 22.5 0.0 9.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 KEY71586.1 - 2.3e-65 214.3 40.0 5.8e-09 35.4 0.0 11.7 11 1 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 KEY71586.1 - 1.4e-43 147.9 0.1 2.1e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 KEY71586.1 - 1e-07 30.5 4.4 0.15 10.1 0.0 5.3 2 2 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KEY71586.1 - 8.4e-07 28.0 5.1 0.017 13.8 0.0 4.3 3 3 0 3 3 3 3 Nup133 N terminal like Nitro_FeMo-Co PF02579.12 KEY71586.1 - 0.15 12.1 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor zf-Nse PF11789.3 KEY71588.1 - 8.1e-20 70.0 0.2 1.3e-19 69.4 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 KEY71588.1 - 0.0017 17.8 0.1 0.0029 17.0 0.1 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger DUF3294 PF07957.6 KEY71588.1 - 0.011 15.2 0.1 0.021 14.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) zf-RING_UBOX PF13445.1 KEY71588.1 - 0.041 13.6 0.1 0.09 12.5 0.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DUF4611 PF15387.1 KEY71588.1 - 4.9 7.3 7.1 2.8 8.1 0.5 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4611) Methyltransf_23 PF13489.1 KEY71589.1 - 6e-22 78.0 0.0 8.9e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY71589.1 - 1.1e-18 67.4 0.0 1.7e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY71589.1 - 4.3e-15 55.6 0.0 5.3e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY71589.1 - 3.3e-14 53.4 0.0 5.5e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY71589.1 - 5.3e-13 49.2 0.0 8.5e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY71589.1 - 1.5e-10 41.1 0.1 6.3e-10 39.1 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY71589.1 - 3.7e-07 30.4 0.0 6.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEY71589.1 - 3e-05 23.2 0.0 4.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 KEY71589.1 - 0.00043 19.0 0.0 0.00063 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 KEY71589.1 - 0.0015 17.9 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 KEY71589.1 - 0.0033 16.5 0.0 0.0076 15.3 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase DHBP_synthase PF00926.14 KEY71590.1 - 2.6e-68 229.1 0.0 6.3e-68 227.8 0.0 1.5 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Atx10homo_assoc PF09759.4 KEY71591.1 - 1.5e-11 43.9 0.0 8.1e-11 41.5 0.0 2.1 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain PNP_UDP_1 PF01048.15 KEY71592.1 - 1.1e-40 139.1 0.1 1.3e-40 138.8 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Methyltransf_33 PF10017.4 KEY71593.1 - 2.6e-23 82.2 0.4 3.7e-23 81.7 0.3 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent MmlI PF09448.5 KEY71593.1 - 0.028 14.1 0.2 0.086 12.5 0.0 1.9 2 0 0 2 2 2 0 Methylmuconolactone methyl-isomerase Fungal_trans_2 PF11951.3 KEY71594.1 - 2.7e-19 69.0 0.0 4.2e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.19 KEY71596.1 - 2.2e-43 148.5 0.0 4.3e-43 147.6 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KEY71596.1 - 1.8e-05 24.5 0.0 0.043 13.5 0.0 2.8 3 0 0 3 3 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KEY71596.1 - 3e-05 24.0 0.0 0.061 13.1 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 KEY71596.1 - 0.00014 21.1 0.0 0.014 14.6 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase Trp_halogenase PF04820.9 KEY71596.1 - 0.00015 20.5 0.1 0.0015 17.2 0.1 2.0 1 1 0 1 1 1 1 Tryptophan halogenase NAD_binding_7 PF13241.1 KEY71596.1 - 0.00023 21.3 0.0 0.00042 20.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 KEY71596.1 - 0.00052 19.9 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KEY71596.1 - 0.00072 19.9 0.0 0.0018 18.6 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY71596.1 - 0.0022 18.0 0.0 0.1 12.6 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEY71596.1 - 0.0044 15.9 5.3 0.42 9.4 3.7 2.2 1 1 0 1 1 1 1 FAD binding domain ThiF PF00899.16 KEY71596.1 - 0.0053 16.5 0.2 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 ThiF family adh_short PF00106.20 KEY71596.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase 3HCDH_N PF02737.13 KEY71596.1 - 0.022 14.4 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KEY71596.1 - 0.026 13.5 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 KEY71596.1 - 0.037 13.4 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 KEY71596.1 - 0.047 13.7 0.2 0.088 12.9 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 KEY71596.1 - 0.062 12.1 0.1 3.6 6.3 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A XdhC_C PF13478.1 KEY71596.1 - 0.069 13.4 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_Gly3P_dh_N PF01210.18 KEY71596.1 - 0.078 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 KEY71596.1 - 0.14 11.1 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 KEY71596.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_1 PF00667.15 KEY71597.1 - 4.4e-60 202.8 0.0 9.7e-60 201.7 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 KEY71597.1 - 2.6e-11 44.0 0.0 9.4e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain POR PF01558.13 KEY71597.1 - 2.6e-05 24.1 0.0 6.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 KEY71597.1 - 0.001 19.0 0.1 0.0027 17.6 0.1 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain HAD_2 PF13419.1 KEY71600.1 - 2.1e-30 106.2 0.2 3.5e-30 105.5 0.1 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEY71600.1 - 0.0033 17.1 0.0 0.0072 16.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like ADH_zinc_N PF00107.21 KEY71600.1 - 0.033 13.7 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Prenyltrans_2 PF13249.1 KEY71600.1 - 0.036 14.4 0.0 2.7 8.4 0.1 2.5 2 0 0 2 2 2 0 Prenyltransferase-like p450 PF00067.17 KEY71601.1 - 2e-24 85.9 0.1 1.3e-23 83.2 0.1 1.9 1 1 1 2 2 2 1 Cytochrome P450 DUF673 PF05054.7 KEY71601.1 - 0.061 11.8 0.1 0.086 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF673) RepB-RCR_reg PF10723.4 KEY71601.1 - 0.13 11.9 0.6 0.24 11.1 0.4 1.4 1 0 0 1 1 1 0 Replication regulatory protein RepB E1-E2_ATPase PF00122.15 KEY71602.1 - 2.3e-47 160.9 0.1 4.8e-47 159.9 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KEY71602.1 - 1.8e-39 136.3 0.3 3.3e-39 135.5 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KEY71602.1 - 1.2e-18 67.0 0.0 2.8e-09 36.9 0.0 3.7 3 0 0 3 3 3 2 Heavy-metal-associated domain HAD PF12710.2 KEY71602.1 - 4.1e-16 59.7 0.0 8.3e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEY71602.1 - 1e-05 25.2 0.1 2e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cyclin_N PF00134.18 KEY71603.1 - 6.9e-13 48.2 0.0 1.2e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KEY71603.1 - 1e-10 42.2 0.1 6.8e-10 39.5 0.0 2.1 2 0 0 2 2 2 1 Cyclin Pkinase PF00069.20 KEY71605.1 - 2.5e-72 243.1 0.0 3.1e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY71605.1 - 1.5e-32 112.7 0.0 1.8e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY71605.1 - 0.0025 16.8 0.0 0.0041 16.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEY71605.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KEY71605.1 - 0.031 13.3 0.0 0.081 11.9 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family UPF0029 PF01205.14 KEY71606.1 - 1.1e-26 92.6 0.1 6e-26 90.2 0.0 2.2 3 0 0 3 3 3 1 Uncharacterized protein family UPF0029 HHH_5 PF14520.1 KEY71606.1 - 0.085 13.0 0.1 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix domain Methyltransf_23 PF13489.1 KEY71607.1 - 8e-12 45.1 0.0 1.4e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY71607.1 - 0.00062 20.1 0.0 0.0049 17.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY71607.1 - 0.00077 19.0 0.0 0.25 10.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 KEY71607.1 - 0.001 19.5 0.0 0.004 17.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY71607.1 - 0.0011 19.4 0.0 0.069 13.6 0.0 2.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY71607.1 - 0.0051 15.9 0.0 0.98 8.4 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEY71607.1 - 0.01 16.1 0.0 0.03 14.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain TFIIF_alpha PF05793.7 KEY71608.1 - 0.17 10.2 2.6 0.32 9.2 1.8 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PhzC-PhzF PF02567.11 KEY71609.1 - 3.3e-38 131.5 0.0 8.3e-38 130.2 0.0 1.6 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Not1 PF04054.10 KEY71610.1 - 1.6e-101 339.9 0.0 1.1e-100 337.1 0.0 2.2 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 KEY71610.1 - 3.9e-48 162.8 1.8 1.3e-47 161.1 1.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) FCH PF00611.18 KEY71611.1 - 1.1e-19 70.4 0.9 3.2e-19 68.9 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 KEY71611.1 - 5.4e-12 44.9 0.0 9.6e-12 44.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KEY71611.1 - 1.1e-11 44.0 0.0 2.3e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KEY71611.1 - 5.2e-11 41.8 0.0 1.9e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain FliD_N PF02465.13 KEY71611.1 - 5.7 7.3 8.4 6.3 7.2 0.0 3.6 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Seipin PF06775.9 KEY71612.1 - 2e-36 125.4 0.0 2.6e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) zf-LITAF-like PF10601.4 KEY71613.1 - 1.4e-11 44.0 0.7 2e-11 43.5 0.5 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Nup84_Nup100 PF04121.8 KEY71615.1 - 2.8e-61 207.1 0.6 9.9e-39 132.6 0.0 3.0 2 1 0 2 2 2 2 Nuclear pore protein 84 / 107 DUF1903 PF08991.5 KEY71617.1 - 6.6e-24 83.8 8.5 7.9e-24 83.6 5.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 KEY71617.1 - 0.024 14.5 5.8 0.024 14.5 4.0 1.6 2 0 0 2 2 2 0 CHCH domain PIP49_C PF12260.3 KEY71617.1 - 0.039 13.3 4.5 0.039 13.3 3.1 1.0 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 NDUFB10 PF10249.4 KEY71617.1 - 0.069 13.3 0.7 0.079 13.1 0.5 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 Rad60-SLD PF11976.3 KEY71618.1 - 1.7e-19 69.2 0.1 2e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KEY71618.1 - 1.4e-08 33.9 0.0 2.3e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family HH_signal PF01085.13 KEY71618.1 - 0.0071 15.9 0.0 0.0078 15.7 0.0 1.0 1 0 0 1 1 1 1 Hedgehog amino-terminal signalling domain SRP9-21 PF05486.7 KEY71618.1 - 0.087 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) LIM PF00412.17 KEY71619.1 - 8.5e-25 86.5 24.2 2.4e-08 33.9 4.2 3.4 3 0 0 3 3 3 3 LIM domain Nudix_N_2 PF14803.1 KEY71619.1 - 0.39 10.4 13.5 2.9 7.6 0.6 5.7 5 0 0 5 5 5 0 Nudix N-terminal CHCH PF06747.8 KEY71620.1 - 1.5e-05 24.7 0.9 3.2e-05 23.7 0.6 1.6 1 1 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 KEY71620.1 - 0.0032 17.1 2.1 0.0046 16.7 1.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 KEY71620.1 - 0.0067 16.4 3.1 0.042 13.9 2.4 1.8 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 KEY71620.1 - 0.033 14.2 3.7 2.5 8.1 0.4 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) GCK PF07802.6 KEY71620.1 - 0.13 12.3 1.7 0.2 11.8 1.2 1.2 1 0 0 1 1 1 0 GCK domain UPF0203 PF05254.7 KEY71620.1 - 0.24 11.2 1.9 20 5.1 0.1 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Dynamin_M PF01031.15 KEY71621.1 - 1e-112 375.7 0.0 3.3e-112 374.0 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KEY71621.1 - 3.9e-56 189.4 0.0 8.9e-56 188.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KEY71621.1 - 2.3e-31 107.5 2.2 2.3e-31 107.5 1.5 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KEY71621.1 - 0.00039 20.3 0.0 0.0014 18.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEY71621.1 - 0.02 15.3 0.0 0.055 13.9 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein zf-CCHC_4 PF14392.1 KEY71621.1 - 0.13 11.9 0.1 0.28 10.8 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF3154 PF11351.3 KEY71622.1 - 0.037 13.7 0.2 0.077 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) F-box PF00646.28 KEY71622.1 - 0.04 13.5 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 F-box domain zf-Di19 PF05605.7 KEY71622.1 - 0.23 11.6 3.3 0.57 10.3 0.1 3.0 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Fungal_trans PF04082.13 KEY71623.1 - 2.1e-15 56.2 0.2 2.1e-15 56.2 0.2 1.9 3 0 0 3 3 3 1 Fungal specific transcription factor domain Glutaredoxin PF00462.19 KEY71624.1 - 1.9e-18 66.2 0.0 2e-17 62.8 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 KEY71624.1 - 8.8e-13 47.8 0.0 2.1e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 KEY71624.1 - 0.13 10.9 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Phosducin Thioredoxin_8 PF13905.1 KEY71624.1 - 0.15 12.2 0.0 5.5 7.1 0.0 2.4 1 1 1 2 2 2 0 Thioredoxin-like ArsC PF03960.10 KEY71624.1 - 0.16 12.0 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 ArsC family SH3_9 PF14604.1 KEY71625.1 - 2e-27 94.5 12.7 4.4e-15 54.9 0.3 2.7 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.23 KEY71625.1 - 6.1e-24 83.1 4.8 1.1e-11 43.9 0.2 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KEY71625.1 - 5.9e-14 51.3 0.0 1.8e-06 27.3 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 KEY71625.1 - 1.7e-11 44.0 0.0 2.9e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ago_hook PF10427.4 KEY71626.1 - 0.024 14.7 0.2 0.034 14.1 0.2 1.3 1 0 0 1 1 1 0 Argonaute hook zf-B_box PF00643.19 KEY71628.1 - 0.058 13.3 3.4 0.12 12.2 2.4 1.5 1 0 0 1 1 1 0 B-box zinc finger eIF-3_zeta PF05091.7 KEY71629.1 - 2.9e-198 659.7 0.0 3.5e-198 659.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.8 KEY71629.1 - 0.012 15.0 0.1 0.027 13.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF569) ICMT PF04140.9 KEY71630.1 - 3.1e-07 30.4 0.1 8.9e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KEY71630.1 - 1.2e-05 25.3 0.6 7.4e-05 22.8 0.4 2.2 1 1 0 1 1 1 1 Phospholipid methyltransferase zf-H2C2_2 PF13465.1 KEY71634.1 - 3.2e-14 52.3 9.3 5.2e-08 32.7 0.2 3.9 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KEY71634.1 - 1e-12 47.5 12.3 8e-06 25.8 1.6 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY71634.1 - 1.7e-08 34.1 20.9 3.9e-05 23.6 1.8 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KEY71634.1 - 0.00052 20.0 14.0 0.03 14.4 0.1 3.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEY71634.1 - 0.0017 18.4 7.6 0.014 15.6 0.2 3.5 4 0 0 4 4 4 2 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.1 KEY71634.1 - 0.21 11.8 0.5 0.48 10.7 0.3 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2H2_6 PF13912.1 KEY71634.1 - 0.35 10.8 7.9 11 6.0 0.4 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger LIM PF00412.17 KEY71634.1 - 1.2 9.2 3.4 9.6 6.3 2.4 2.2 1 1 1 2 2 2 0 LIM domain AOX PF01786.12 KEY71635.1 - 1.6e-84 282.4 0.0 2e-84 282.1 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase tRNA-synt_1d PF00750.14 KEY71636.1 - 2.9e-80 269.7 1.1 4.8e-80 269.0 0.8 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KEY71636.1 - 6.3e-28 97.1 0.2 1.3e-27 96.1 0.2 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 KEY71636.1 - 0.0002 21.8 0.0 0.0005 20.5 0.0 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain eIF3_subunit PF08597.5 KEY71637.1 - 6.1e-67 225.7 26.3 6.7e-67 225.6 18.2 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit CDC27 PF09507.5 KEY71637.1 - 8.6 5.4 31.9 0.38 9.9 14.4 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 MDM31_MDM32 PF08118.6 KEY71638.1 - 8.8e-185 614.9 0.2 1.2e-184 614.4 0.1 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins TraH_2 PF06871.6 KEY71638.1 - 0.017 14.5 0.1 0.033 13.6 0.1 1.3 1 0 0 1 1 1 0 TraH_2 KH_1 PF00013.24 KEY71639.1 - 4.2e-05 23.0 1.3 7.7e-05 22.2 0.4 1.7 2 0 0 2 2 2 1 KH domain Enolase_C PF00113.17 KEY71640.1 - 2.9e-153 509.0 0.1 3.9e-153 508.6 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KEY71640.1 - 6.9e-58 194.2 0.2 1.2e-57 193.5 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE PF01188.16 KEY71640.1 - 0.032 14.7 0.0 0.074 13.5 0.0 1.7 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAAL_C PF07476.6 KEY71640.1 - 0.052 12.4 0.4 0.5 9.2 0.1 2.3 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus PAG PF15347.1 KEY71640.1 - 0.079 12.0 0.3 3.1 6.8 0.1 2.1 1 1 1 2 2 2 0 Phosphoprotein associated with glycosphingolipid-enriched MR_MLE_C PF13378.1 KEY71640.1 - 0.082 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Enolase C-terminal domain-like Mad3_BUB1_I PF08311.7 KEY71641.1 - 3.6e-43 146.3 0.1 1.2e-42 144.6 0.1 1.8 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 KEY71641.1 - 6.8e-14 51.6 0.0 1.1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY71641.1 - 9.2e-05 21.6 0.0 0.00056 19.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY71641.1 - 0.087 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like AP_endonuc_2 PF01261.19 KEY71642.1 - 3.5e-30 104.8 1.3 5.3e-30 104.3 0.9 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel HSCB_C PF07743.8 KEY71642.1 - 0.52 10.8 6.7 14 6.2 0.0 3.0 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain DAGAT PF03982.8 KEY71643.1 - 3e-89 298.6 0.0 3.9e-89 298.2 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase zf-H2C2_2 PF13465.1 KEY71644.1 - 3.7e-12 45.8 18.9 2e-06 27.8 1.6 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KEY71644.1 - 1.2e-10 41.1 22.8 0.0018 18.4 5.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY71644.1 - 8e-07 28.9 19.7 0.0028 17.8 4.4 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KEY71644.1 - 0.00083 19.4 10.8 0.19 11.9 2.6 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KEY71644.1 - 0.04 13.8 10.4 1.6 8.6 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-CHCC PF10276.4 KEY71644.1 - 0.042 13.6 2.1 1.7 8.5 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger domain TMF_DNA_bd PF12329.3 KEY71644.1 - 0.052 13.3 0.1 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding zf-CHY PF05495.7 KEY71644.1 - 0.54 10.4 7.9 1.2 9.3 5.5 1.6 1 0 0 1 1 1 0 CHY zinc finger zf-C2HC_2 PF13913.1 KEY71644.1 - 0.79 9.4 5.2 0.43 10.3 0.3 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DZR PF12773.2 KEY71644.1 - 2.8 7.8 5.8 36 4.2 4.0 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-Di19 PF05605.7 KEY71644.1 - 8.4 6.6 11.0 1.7 8.8 4.4 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.5 KEY71644.1 - 8.7 6.3 9.0 17 5.4 0.2 3.0 1 1 2 3 3 3 0 Zinc ribbon domain zf-C2H2_2 PF12756.2 KEY71644.1 - 9.7 6.3 12.6 1.2 9.3 1.4 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Spc7 PF08317.6 KEY71645.1 - 0.068 11.8 0.3 0.07 11.7 0.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-U1 PF06220.7 KEY71645.1 - 0.31 10.6 1.2 0.48 10.0 0.8 1.3 1 0 0 1 1 1 0 U1 zinc finger DUF3425 PF11905.3 KEY71646.1 - 2.3e-15 56.6 0.0 4.9e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) adh_short PF00106.20 KEY71646.1 - 4.2e-06 26.7 0.0 1.7e-05 24.7 0.0 1.9 2 1 0 2 2 2 1 short chain dehydrogenase adh_short PF00106.20 KEY71647.1 - 1.4e-27 96.6 0.5 2e-27 96.1 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY71647.1 - 1e-25 90.9 0.0 1.3e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY71647.1 - 8.7e-08 32.0 1.4 1e-06 28.5 1.0 2.0 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KEY71647.1 - 0.093 12.5 0.1 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Fungal_trans_2 PF11951.3 KEY71648.1 - 2.5e-07 29.6 0.2 0.0036 15.9 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain DTW PF03942.10 KEY71649.1 - 0.032 13.4 0.2 0.068 12.3 0.1 1.6 2 0 0 2 2 2 0 DTW domain zf-BED PF02892.10 KEY71649.1 - 0.056 13.1 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 BED zinc finger DUF3426 PF11906.3 KEY71649.1 - 0.11 12.1 0.0 0.51 9.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3426) Sugar_tr PF00083.19 KEY71650.1 - 1.4e-78 264.5 28.9 1.5e-78 264.3 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY71650.1 - 7.7e-27 93.9 53.1 8e-25 87.2 22.8 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KEY71650.1 - 0.016 14.9 2.5 0.16 11.7 0.1 3.1 3 0 0 3 3 3 0 MFS_1 like family TPR_10 PF13374.1 KEY71651.1 - 7.1e-24 82.9 0.0 1.9e-11 43.4 0.0 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEY71651.1 - 2.3e-18 65.8 0.3 1.5e-15 56.8 0.0 1.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEY71651.1 - 1.1e-08 34.2 0.1 0.001 18.7 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEY71651.1 - 2.1e-06 27.4 0.4 0.011 15.8 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEY71651.1 - 6.4e-06 25.5 0.1 0.014 15.0 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEY71651.1 - 2.3e-05 23.9 0.1 0.014 15.3 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEY71651.1 - 0.00034 20.1 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 KEY71651.1 - 0.0024 17.5 0.1 1.8 8.5 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEY71651.1 - 0.018 15.3 0.1 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_5 PF12688.2 KEY71651.1 - 0.024 14.6 0.0 0.027 14.4 0.0 1.1 1 0 0 1 1 1 0 Tetratrico peptide repeat TPR_14 PF13428.1 KEY71651.1 - 0.033 14.7 0.0 12 6.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEY71651.1 - 0.034 14.6 0.1 12 6.6 0.0 2.5 3 0 0 3 3 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KEY71651.1 - 0.052 13.6 0.0 0.57 10.3 0.0 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2664 PF10867.3 KEY71651.1 - 0.085 13.4 0.1 12 6.6 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2664) DUF4132 PF13569.1 KEY71652.1 - 0.029 13.9 1.0 2.4 7.6 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4132) Cellulase-like PF12876.2 KEY71652.1 - 0.1 13.0 0.1 1.8 9.0 0.0 2.7 3 0 0 3 3 3 0 Sugar-binding cellulase-like WD40 PF00400.27 KEY71653.1 - 3.3e-32 109.1 6.2 1.2e-15 56.7 0.3 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 KEY71653.1 - 0.0015 16.7 0.1 0.34 8.9 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KEY71653.1 - 0.0055 15.0 0.0 0.014 13.7 0.0 1.6 1 1 0 1 1 1 1 Cytochrome D1 heme domain DPPIV_N PF00930.16 KEY71654.1 - 5.8e-53 179.7 0.0 8.7e-53 179.1 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KEY71654.1 - 1.9e-43 148.1 0.3 3.2e-43 147.4 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEY71654.1 - 4.4e-08 32.9 0.2 1.1e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KEY71654.1 - 4.2e-05 23.1 0.3 0.00017 21.1 0.0 2.1 2 0 0 2 2 2 1 Putative esterase DLH PF01738.13 KEY71654.1 - 0.0011 18.3 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.6 KEY71654.1 - 0.015 15.0 0.1 0.52 9.9 0.0 2.2 1 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Tannase PF07519.6 KEY71654.1 - 0.024 13.3 0.0 0.038 12.6 0.0 1.3 1 0 0 1 1 1 0 Tannase and feruloyl esterase FSH1 PF03959.8 KEY71654.1 - 0.087 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Glyco_hydro_43 PF04616.9 KEY71657.1 - 6.6e-51 173.0 5.3 8.3e-51 172.7 3.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KEY71657.1 - 0.012 15.0 0.9 0.012 15.0 0.6 1.5 2 0 0 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain PAF-AH_p_II PF03403.8 KEY71658.1 - 1.3e-12 46.7 0.0 9.2e-07 27.4 0.0 2.7 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KEY71658.1 - 6.1e-12 45.5 0.0 1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY71658.1 - 7e-08 32.6 0.3 1.6e-07 31.4 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KEY71658.1 - 5.1e-07 28.8 0.0 1.2e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KEY71658.1 - 0.00055 18.8 0.1 0.0051 15.6 0.0 2.2 2 1 0 2 2 2 1 Chlorophyllase Lipase_3 PF01764.20 KEY71658.1 - 0.072 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Fungal_trans PF04082.13 KEY71660.1 - 2.7e-05 23.1 1.4 6.5e-05 21.9 0.7 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 KEY71661.1 - 7.9e-26 90.9 0.0 3.7e-16 59.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KEY71661.1 - 0.00011 22.1 0.1 0.00026 20.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KEY71661.1 - 0.00052 18.7 0.0 0.019 13.5 0.1 2.7 3 0 0 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.9 KEY71661.1 - 0.00088 17.8 0.0 0.018 13.5 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein SE PF08491.5 KEY71661.1 - 0.0017 17.2 0.0 0.016 14.0 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_3 PF13738.1 KEY71661.1 - 0.0022 18.1 0.0 0.0049 16.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEY71661.1 - 0.0063 16.4 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY71661.1 - 0.0063 16.8 0.1 6.6 7.2 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEY71661.1 - 0.016 14.1 0.0 0.12 11.2 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEY71661.1 - 0.017 14.0 0.0 0.39 9.5 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.12 KEY71661.1 - 0.027 13.5 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 KEY71661.1 - 0.066 12.0 0.3 0.11 11.3 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Melibiase PF02065.13 KEY71662.1 - 2.7e-17 62.5 0.3 7.4e-12 44.6 0.0 2.9 2 1 0 2 2 2 2 Melibiase Fungal_trans PF04082.13 KEY71663.1 - 1.2e-07 30.9 0.0 2.9e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 KEY71664.1 - 7.6e-77 258.7 18.2 8.6e-77 258.6 12.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY71664.1 - 3e-20 72.2 11.7 3e-20 72.2 8.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily WD40 PF00400.27 KEY71667.1 - 9.7e-91 294.7 22.6 2.7e-15 55.5 0.2 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KEY71667.1 - 8.2e-18 63.8 0.1 3.8e-05 22.1 0.0 4.0 1 1 3 4 4 4 4 Cytochrome D1 heme domain Nup160 PF11715.3 KEY71667.1 - 2.9e-10 38.9 3.1 0.087 10.9 0.0 5.7 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Robl_LC7 PF03259.12 KEY71667.1 - 1.3e-07 31.1 0.2 15 5.2 0.0 5.9 6 0 0 6 6 6 0 Roadblock/LC7 domain PD40 PF07676.7 KEY71667.1 - 7e-07 28.7 2.1 2.9 7.6 0.0 6.6 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Plectin PF00681.15 KEY71667.1 - 0.0011 18.4 1.0 1.4e+02 2.1 0.0 5.9 7 0 0 7 7 7 0 Plectin repeat DUF1416 PF07210.7 KEY71667.1 - 0.0031 17.0 0.0 30 4.3 0.0 4.9 3 1 3 6 6 6 0 Protein of unknown function (DUF1416) Fascin PF06268.8 KEY71667.1 - 0.0043 17.1 0.0 2.8 8.0 0.0 3.3 2 1 2 4 4 4 1 Fascin domain Proteasome_A_N PF10584.4 KEY71667.1 - 0.0051 16.1 4.2 94 2.4 0.0 6.2 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature DUF1150 PF06620.6 KEY71667.1 - 0.0069 16.1 0.0 39 4.1 0.0 4.7 6 0 0 6 6 6 0 Protein of unknown function (DUF1150) DUF1258 PF06869.7 KEY71667.1 - 0.015 14.4 1.3 4.1 6.4 0.0 3.6 1 1 2 4 4 4 0 Protein of unknown function (DUF1258) Coatomer_WDAD PF04053.9 KEY71667.1 - 0.033 12.9 0.0 0.16 10.7 0.0 1.9 1 1 1 2 2 2 0 Coatomer WD associated region T2SN PF01203.14 KEY71667.1 - 0.071 12.6 0.5 6.1 6.3 0.0 3.0 3 2 1 4 4 4 0 Type II secretion system (T2SS), protein N TruB_C PF09142.6 KEY71667.1 - 0.093 12.3 0.0 14 5.4 0.0 4.0 5 0 0 5 5 5 0 tRNA Pseudouridine synthase II, C terminal SecA_PP_bind PF01043.15 KEY71667.1 - 0.13 12.6 0.0 14 6.0 0.0 3.6 3 3 2 5 5 5 0 SecA preprotein cross-linking domain DUF1283 PF06932.6 KEY71667.1 - 0.41 10.6 2.5 40 4.3 0.0 4.5 6 0 0 6 6 6 0 Protein of unknown function (DUF1283) NACHT PF05729.7 KEY71668.1 - 4.2e-21 75.3 0.1 1.3e-20 73.6 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KEY71668.1 - 0.00012 22.1 0.1 0.00042 20.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEY71668.1 - 0.0006 19.9 1.3 0.012 15.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 KEY71668.1 - 0.0029 17.2 0.4 0.39 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEY71668.1 - 0.026 14.2 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 KEY71668.1 - 0.1 12.7 0.0 0.35 11.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase HSP70 PF00012.15 KEY71668.1 - 0.32 8.8 3.9 0.55 8.0 2.7 1.2 1 0 0 1 1 1 0 Hsp70 protein CorA PF01544.13 KEY71668.1 - 1.9 7.4 6.3 4.7 6.1 4.4 1.7 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1764 PF08576.5 KEY71669.1 - 7.3 7.4 11.5 5.5 7.8 4.8 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) YqfQ PF14181.1 KEY71669.1 - 9.7 6.2 14.2 0.18 11.8 3.9 2.0 2 0 0 2 2 2 0 YqfQ-like protein F-box-like PF12937.2 KEY71671.1 - 7.8e-06 25.5 1.0 7.8e-06 25.5 0.7 2.1 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 KEY71671.1 - 0.0014 18.3 0.2 0.0041 16.8 0.2 1.9 1 1 0 1 1 1 1 F-box-like domain Pyr_redox_2 PF07992.9 KEY71672.1 - 9.4e-25 87.6 2.0 4.1e-24 85.5 1.4 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY71672.1 - 4.2e-14 52.7 1.9 4.3e-13 49.4 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KEY71672.1 - 4.8e-14 51.7 0.0 1.2e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Reductase_C PF14759.1 KEY71672.1 - 6.8e-06 26.2 0.0 1.6e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Reductase C-terminal DAO PF01266.19 KEY71672.1 - 6.5e-05 21.9 1.2 0.26 10.1 0.0 3.6 1 1 2 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KEY71672.1 - 0.00016 20.6 0.0 0.23 10.3 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KEY71672.1 - 0.00083 19.1 0.4 2.5 7.8 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding DUF1188 PF06690.6 KEY71672.1 - 0.064 12.3 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Zn_clus PF00172.13 KEY71673.1 - 0.00062 19.6 4.3 0.0013 18.6 3.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY71673.1 - 0.0015 17.4 0.0 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3490 PF11995.3 KEY71673.1 - 0.0074 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3490) DivIVA PF05103.8 KEY71674.1 - 0.05 13.6 18.8 8.3 6.4 0.0 3.6 2 1 0 2 2 2 0 DivIVA protein Tropomyosin_1 PF12718.2 KEY71674.1 - 0.28 11.0 30.1 0.038 13.8 17.0 2.3 1 1 1 2 2 2 0 Tropomyosin like Laminin_II PF06009.7 KEY71674.1 - 8 6.2 14.0 0.51 10.0 2.8 3.2 1 1 3 4 4 4 0 Laminin Domain II adh_short PF00106.20 KEY71675.1 - 7.2e-17 61.8 0.0 1.6e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY71675.1 - 1.1e-09 38.1 0.1 2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY71675.1 - 8.2e-07 29.0 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 KEY71675.1 - 0.0033 17.5 0.0 0.0057 16.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF3073 PF11273.3 KEY71675.1 - 0.087 13.3 0.2 0.22 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3073) tRNA-synt_2 PF00152.15 KEY71676.1 - 2.1e-65 220.7 0.0 3.2e-65 220.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KEY71676.1 - 0.00018 21.2 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Oxidored_FMN PF00724.15 KEY71677.1 - 6.9e-41 140.3 0.0 9.2e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 KEY71677.1 - 0.00089 18.5 0.0 0.014 14.7 0.0 2.2 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Fungal_trans PF04082.13 KEY71678.1 - 4.6e-21 74.8 0.0 7.3e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY71678.1 - 1e-07 31.7 9.2 1.9e-07 30.8 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aa_trans PF01490.13 KEY71679.1 - 3.2e-17 62.1 19.2 3.2e-17 62.1 13.3 2.6 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein Vma12 PF11712.3 KEY71679.1 - 1.2 8.8 0.0 1.2 8.8 0.0 3.0 4 0 0 4 4 4 0 Endoplasmic reticulum-based factor for assembly of V-ATPase p450 PF00067.17 KEY71681.1 - 5.9e-61 206.3 0.0 8e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3154 PF11351.3 KEY71681.1 - 0.065 12.9 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) Pro_CA PF00484.14 KEY71683.1 - 1.2e-24 87.0 0.1 1.9e-24 86.4 0.1 1.3 1 0 0 1 1 1 1 Carbonic anhydrase Fungal_trans PF04082.13 KEY71685.1 - 4.5e-29 101.1 0.0 6.5e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY71685.1 - 2.2e-08 33.8 11.9 5.5e-08 32.5 8.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_2 PF00890.19 KEY71686.1 - 4.8e-32 111.3 0.0 7.6e-31 107.3 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KEY71686.1 - 1.9e-06 26.6 0.7 0.053 11.9 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein DAO PF01266.19 KEY71686.1 - 3e-06 26.4 0.9 1.8e-05 23.7 0.6 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KEY71686.1 - 1.4e-05 24.3 0.6 7.1e-05 22.0 0.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEY71686.1 - 0.003 17.4 0.0 0.026 14.4 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY71686.1 - 0.0041 17.1 0.1 0.012 15.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KEY71686.1 - 0.0067 15.5 0.0 0.014 14.4 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KEY71686.1 - 0.016 15.2 0.0 0.7 9.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY71686.1 - 0.03 13.2 0.0 0.059 12.2 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 KEY71686.1 - 0.068 12.0 0.4 0.22 10.3 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF1998 PF09369.5 KEY71686.1 - 0.12 13.0 0.0 0.36 11.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1998) MFS_1 PF07690.11 KEY71687.1 - 2.1e-23 82.6 41.4 3.1e-13 49.1 11.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_tail_X PF05489.7 KEY71687.1 - 0.0097 15.3 1.9 0.027 13.9 0.5 2.2 2 0 0 2 2 2 1 Phage Tail Protein X Sugar_tr PF00083.19 KEY71687.1 - 0.26 9.8 34.3 18 3.7 23.8 3.0 1 1 0 1 1 1 0 Sugar (and other) transporter DUF1228 PF06779.9 KEY71687.1 - 2.1 8.4 13.9 5.9 6.9 0.1 4.2 4 2 0 4 4 4 0 Protein of unknown function (DUF1228) Condensation PF00668.15 KEY71688.1 - 0.0026 16.6 0.0 0.15 10.8 0.0 2.2 2 0 0 2 2 2 2 Condensation domain AATase PF07247.7 KEY71688.1 - 0.088 11.3 0.0 0.48 8.9 0.0 1.8 1 1 0 1 1 1 0 Alcohol acetyltransferase Beta-lactamase PF00144.19 KEY71689.1 - 1.7e-29 102.8 0.4 2.6e-29 102.3 0.3 1.1 1 0 0 1 1 1 1 Beta-lactamase adh_short PF00106.20 KEY71690.1 - 2e-18 66.8 0.2 3.1e-18 66.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY71690.1 - 1.5e-08 34.5 0.2 2.4e-08 33.8 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY71690.1 - 6.3e-07 29.4 0.3 1.3e-06 28.4 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEY71690.1 - 7.7e-05 22.2 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY71690.1 - 0.013 15.5 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding DUF3425 PF11905.3 KEY71691.1 - 4.9e-27 94.4 0.0 1.3e-26 93.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Methyltransf_18 PF12847.2 KEY71692.1 - 5.6e-11 43.0 0.0 9e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY71692.1 - 1.5e-09 38.1 0.0 2.4e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY71692.1 - 2e-09 37.8 0.0 3.2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY71692.1 - 1.2e-08 34.8 0.0 1.6e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY71692.1 - 2e-08 34.4 0.0 3.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY71692.1 - 2.3e-08 33.7 0.0 5e-08 32.6 0.0 1.4 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY71692.1 - 1.8e-07 30.5 0.0 2.4e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KEY71692.1 - 5e-06 26.5 0.0 8.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY71692.1 - 1.6e-05 24.3 0.0 2.4e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 KEY71692.1 - 0.00051 19.4 0.0 0.00066 19.1 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) NNMT_PNMT_TEMT PF01234.12 KEY71692.1 - 0.0016 17.4 0.0 0.0051 15.8 0.0 1.7 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family CMAS PF02353.15 KEY71692.1 - 0.0049 15.9 0.0 0.007 15.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.10 KEY71692.1 - 0.02 14.2 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Rsm22 PF09243.5 KEY71692.1 - 0.021 13.8 0.0 0.027 13.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Acetyltransf_1 PF00583.19 KEY71693.1 - 3.9e-09 36.4 0.2 5.9e-09 35.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEY71693.1 - 2.7e-07 30.6 0.1 3.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEY71693.1 - 7.2e-05 22.8 0.0 9.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KEY71693.1 - 0.00078 19.4 0.0 0.0013 18.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KEY71693.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain GFA PF04828.9 KEY71694.1 - 0.0052 16.6 0.1 0.014 15.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DUF3754 PF12576.3 KEY71695.1 - 2.9 7.5 5.1 0.91 9.1 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3754) FAD_binding_4 PF01565.18 KEY71696.1 - 2.3e-20 72.5 2.0 4.6e-20 71.5 1.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY71696.1 - 0.07 13.0 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Berberine and berberine like AAA PF00004.24 KEY71697.1 - 1.2e-17 64.3 0.0 2.2e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEY71697.1 - 1e-05 26.3 0.0 4.4e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEY71697.1 - 0.00016 21.8 0.1 0.004 17.2 0.0 2.5 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.12 KEY71697.1 - 0.0061 15.9 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 KEY71697.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KEY71697.1 - 0.022 14.7 0.0 0.089 12.7 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain RuvB_N PF05496.7 KEY71697.1 - 0.038 13.0 0.0 0.092 11.7 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KEY71697.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 KEY71697.1 - 0.085 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 KEY71697.1 - 0.23 10.1 0.0 0.36 9.5 0.0 1.2 1 0 0 1 1 1 0 ArgK protein DUF465 PF04325.8 KEY71699.1 - 0.048 13.3 2.9 0.082 12.6 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF465) DMPK_coil PF08826.5 KEY71699.1 - 0.16 11.8 0.7 0.34 10.8 0.1 1.8 2 0 0 2 2 2 0 DMPK coiled coil domain like Trp_DMAT PF11991.3 KEY71700.1 - 2.3e-78 263.9 0.0 2.9e-78 263.6 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Glyco_hydro_61 PF03443.9 KEY71701.1 - 5.8e-47 160.3 0.0 6.8e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fungal_trans PF04082.13 KEY71702.1 - 2.9e-18 65.6 0.4 6.5e-18 64.5 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY71702.1 - 5.9e-05 22.8 7.9 5.9e-05 22.8 5.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M20 PF01546.23 KEY71703.1 - 1.4e-29 102.9 0.1 2.1e-29 102.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KEY71703.1 - 1.1e-05 25.1 0.0 2.9e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KEY71703.1 - 0.00018 21.3 0.0 0.00037 20.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 SpecificRecomb PF10136.4 KEY71703.1 - 0.1 10.6 0.0 0.16 10.0 0.0 1.3 1 0 0 1 1 1 0 Site-specific recombinase DUF1989 PF09347.5 KEY71704.1 - 3.4e-52 176.2 0.1 1.6e-51 174.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1989) Polysacc_deac_1 PF01522.16 KEY71704.1 - 7.2e-20 70.8 0.0 1.4e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 KEY71704.1 - 0.0021 17.5 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF4105 PF13387.1 KEY71704.1 - 0.18 10.9 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) FAD_binding_3 PF01494.14 KEY71705.1 - 1.2e-67 228.4 0.0 1.5e-67 228.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 KEY71705.1 - 3.5e-05 22.6 0.0 7.6e-05 21.5 0.0 1.5 2 0 0 2 2 2 1 Tryptophan halogenase Phe_hydrox_dim PF07976.7 KEY71705.1 - 5.5e-05 22.8 0.1 0.00019 21.0 0.0 1.9 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.9 KEY71705.1 - 9.8e-05 22.3 0.3 0.004 17.0 0.1 3.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEY71705.1 - 0.00012 21.1 0.1 0.0003 19.8 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KEY71705.1 - 0.00049 19.2 0.0 0.00083 18.5 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KEY71705.1 - 0.0017 17.3 0.0 0.0044 15.9 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KEY71705.1 - 0.0021 18.0 0.0 0.007 16.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KEY71705.1 - 0.0065 15.4 0.0 0.0096 14.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KEY71705.1 - 0.0086 16.1 0.1 0.024 14.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY71705.1 - 0.0093 16.3 0.1 0.021 15.2 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEY71705.1 - 0.021 13.3 0.0 0.034 12.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 KEY71705.1 - 0.081 12.0 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KEY71705.1 - 0.091 11.8 0.2 0.2 10.7 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase MFS_1 PF07690.11 KEY71706.1 - 6.7e-37 127.0 28.2 6.7e-37 127.0 19.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_3 PF13302.1 KEY71707.1 - 1.4e-11 44.7 0.0 1.6e-11 44.5 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KEY71707.1 - 1.3e-05 25.1 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEY71707.1 - 0.0022 17.9 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KEY71707.1 - 0.015 15.2 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain YfhD PF14151.1 KEY71709.1 - 0.00026 21.0 0.0 0.00059 19.8 0.0 1.6 1 0 0 1 1 1 1 YfhD-like protein OmdA PF13376.1 KEY71710.1 - 1.1e-22 79.4 0.0 1.9e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated Glyco_hydro_76 PF03663.9 KEY71712.1 - 2.6e-140 467.9 6.3 3.3e-140 467.6 4.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KEY71712.1 - 0.00015 20.9 1.5 0.4 9.6 0.1 2.9 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 Ank_2 PF12796.2 KEY71713.1 - 4.8e-26 90.9 0.1 4.5e-14 52.5 0.0 3.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) adh_short PF00106.20 KEY71713.1 - 9.7e-21 74.3 0.0 2.2e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Ank PF00023.25 KEY71713.1 - 1.5e-18 65.5 0.0 7.7e-07 28.6 0.0 5.0 5 0 0 5 5 4 3 Ankyrin repeat PNP_UDP_1 PF01048.15 KEY71713.1 - 1.6e-15 56.7 0.2 3.2e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily Ank_3 PF13606.1 KEY71713.1 - 3.8e-14 51.3 0.0 3.6e-06 26.6 0.0 4.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KEY71713.1 - 1.9e-13 50.5 0.0 2.4e-05 24.7 0.0 4.3 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY71713.1 - 9.6e-11 41.5 0.2 1.1e-05 25.4 0.2 4.2 2 1 2 4 4 3 3 Ankyrin repeats (many copies) NACHT PF05729.7 KEY71713.1 - 6.9e-09 35.5 0.1 2e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 NACHT domain KR PF08659.5 KEY71713.1 - 1.7e-06 27.8 0.0 4.6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY71713.1 - 8.1e-06 25.7 0.0 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AAA_22 PF13401.1 KEY71713.1 - 1.6e-05 25.0 0.0 4.6e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEY71713.1 - 3.7e-05 23.7 0.7 0.00012 22.0 0.5 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KEY71713.1 - 4.7e-05 23.6 0.0 0.00024 21.2 0.0 2.3 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) F420_oxidored PF03807.12 KEY71713.1 - 0.00038 20.8 0.5 0.0013 19.0 0.3 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 KEY71713.1 - 0.00039 19.9 0.0 0.00079 18.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KEY71713.1 - 0.0013 18.8 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_19 PF13245.1 KEY71713.1 - 0.0086 15.8 0.1 0.28 10.9 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain KAP_NTPase PF07693.9 KEY71713.1 - 0.014 14.3 3.0 0.02 13.9 0.2 2.0 1 1 0 2 2 2 0 KAP family P-loop domain NAD_binding_10 PF13460.1 KEY71713.1 - 0.016 15.2 0.7 0.052 13.5 0.1 2.2 2 0 0 2 2 2 0 NADH(P)-binding AAA_30 PF13604.1 KEY71713.1 - 0.027 14.0 1.2 0.12 11.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 KEY71713.1 - 0.046 13.4 0.0 0.1 12.3 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 KEY71713.1 - 0.061 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Polysacc_synt_2 PF02719.10 KEY71713.1 - 0.085 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 KEY71713.1 - 0.13 11.9 0.4 0.3 10.7 0.3 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NTPase_1 PF03266.10 KEY71713.1 - 0.19 11.4 0.1 0.48 10.1 0.1 1.7 1 1 0 1 1 1 0 NTPase OPT PF03169.10 KEY71714.1 - 7.3e-12 44.5 0.2 9.5e-12 44.1 0.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Amidase PF01425.16 KEY71715.1 - 3.8e-18 65.5 0.2 6.8e-13 48.2 0.0 2.0 2 0 0 2 2 2 2 Amidase DisA_N PF02457.11 KEY71715.1 - 0.14 11.2 0.0 0.3 10.2 0.0 1.6 1 1 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding Salp15 PF12115.3 KEY71716.1 - 0.0098 16.1 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 1 Salivary protein of 15kDa inhibits CD4+ T cell activation Herpes_gE PF02480.11 KEY71717.1 - 0.00096 17.5 1.1 0.0012 17.2 0.8 1.0 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF2668 PF10873.3 KEY71717.1 - 0.0045 17.1 0.4 0.0065 16.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2668) CD34_antigen PF06365.7 KEY71717.1 - 0.01 15.5 0.4 0.013 15.1 0.3 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.1 KEY71717.1 - 0.012 15.9 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 KEY71717.1 - 0.023 14.8 0.1 0.029 14.5 0.1 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4190 PF13828.1 KEY71717.1 - 0.028 13.9 0.6 0.052 13.0 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) RCR PF12273.3 KEY71717.1 - 0.036 14.6 0.1 0.036 14.6 0.1 2.0 3 0 0 3 3 2 0 Chitin synthesis regulation, resistance to Congo red DUF456 PF04306.8 KEY71717.1 - 0.052 13.5 0.2 0.066 13.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF1183 PF06682.7 KEY71717.1 - 0.068 12.7 0.0 0.075 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF2062 PF09835.4 KEY71717.1 - 0.07 12.7 0.2 0.096 12.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Mid2 PF04478.7 KEY71717.1 - 0.084 12.2 0.1 0.098 12.0 0.1 1.1 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF3147 PF11345.3 KEY71717.1 - 0.087 12.8 0.1 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3147) CopD PF05425.8 KEY71717.1 - 0.091 12.9 1.0 0.15 12.2 0.7 1.4 1 0 0 1 1 1 0 Copper resistance protein D Sarcoglycan_2 PF05510.8 KEY71717.1 - 0.096 10.9 0.0 0.11 10.7 0.0 1.0 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon SKG6 PF08693.5 KEY71717.1 - 0.11 11.7 6.1 0.24 10.7 4.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 KEY71717.1 - 0.17 11.4 10.8 0.3 10.6 7.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Rhabdo_glycop PF00974.13 KEY71717.1 - 0.22 9.7 0.6 0.27 9.4 0.4 1.0 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Hum_adeno_E3A PF05393.6 KEY71717.1 - 0.57 9.8 3.5 0.85 9.3 2.5 1.2 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Prominin PF05478.6 KEY71717.1 - 0.69 7.3 3.0 0.77 7.2 2.1 1.0 1 0 0 1 1 1 0 Prominin Mac PF12464.3 KEY71718.1 - 4.1e-19 68.3 0.0 5.7e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 KEY71718.1 - 4e-15 54.5 8.2 5.4e-12 44.6 5.0 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KEY71718.1 - 1.6e-13 49.9 6.4 1.2e-11 43.9 4.2 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Abhydrolase_5 PF12695.2 KEY71719.1 - 1.6e-10 40.9 0.6 2.4e-10 40.3 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 KEY71719.1 - 2.6e-06 25.9 0.0 0.00075 17.9 0.0 2.3 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.2 KEY71719.1 - 0.00023 21.1 8.2 0.00048 20.0 5.7 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KEY71719.1 - 0.00074 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 KEY71719.1 - 0.055 12.6 0.2 0.16 11.1 0.1 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family Nucleoporin_FG PF13634.1 KEY71719.1 - 0.082 13.1 2.2 0.14 12.4 1.6 1.2 1 0 0 1 1 1 0 Nucleoporin FG repeat region p450 PF00067.17 KEY71720.1 - 6.2e-57 193.1 0.0 8.1e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 KEY71722.1 - 2.9e-26 91.6 1.3 5.8e-26 90.6 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY71722.1 - 1.5e-08 34.3 0.0 2.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like GCV_T PF01571.16 KEY71722.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain Aldo_ket_red PF00248.16 KEY71723.1 - 9.6e-62 208.3 0.0 1.1e-61 208.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.23 KEY71724.1 - 2e-81 273.5 0.2 2e-81 273.5 0.1 1.7 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEY71724.1 - 0.001 19.9 0.0 0.0028 18.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF4079 PF13301.1 KEY71724.1 - 0.0027 17.7 2.8 0.0062 16.5 1.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) NAD_binding_1 PF00175.16 KEY71724.1 - 0.028 14.9 0.0 0.073 13.6 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Cactin_mid PF10312.4 KEY71724.1 - 0.28 10.3 0.0 0.52 9.5 0.0 1.3 1 0 0 1 1 1 0 Conserved mid region of cactin ECH PF00378.15 KEY71725.1 - 2.1e-64 217.0 0.1 2.4e-64 216.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KEY71725.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Peptidase_S49 PF01343.13 KEY71725.1 - 0.046 13.4 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 NACHT PF05729.7 KEY71726.1 - 1.6e-09 37.6 0.0 3.9e-09 36.3 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 KEY71726.1 - 0.00034 21.4 0.1 0.0031 18.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEY71726.1 - 0.0056 16.6 0.0 0.12 12.4 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KEY71726.1 - 0.0057 16.9 0.1 0.042 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KEY71726.1 - 0.022 14.9 0.0 0.067 13.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 KEY71726.1 - 0.047 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KEY71726.1 - 0.088 12.9 0.0 0.31 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KEY71726.1 - 0.11 11.8 0.1 0.53 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.24 KEY71726.1 - 0.12 12.5 0.0 0.54 10.4 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KEY71726.1 - 0.21 11.8 0.4 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Cupin_2 PF07883.6 KEY71727.1 - 7.2e-15 54.2 0.1 1.2e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 KEY71727.1 - 4.7e-08 32.3 0.0 6.9e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) 3-HAO PF06052.7 KEY71727.1 - 3.5e-05 23.2 0.1 4.1e-05 23.0 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_6 PF12852.2 KEY71727.1 - 0.00017 21.2 0.0 0.00019 21.1 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_1 PF00190.17 KEY71727.1 - 0.0015 18.0 0.1 0.0023 17.3 0.0 1.4 1 1 0 1 1 1 1 Cupin EutQ PF06249.7 KEY71727.1 - 0.0024 17.4 0.0 0.0034 16.9 0.0 1.4 1 1 0 1 1 1 1 Ethanolamine utilisation protein EutQ AraC_binding PF02311.14 KEY71727.1 - 0.0074 15.9 0.0 0.0096 15.6 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain cNMP_binding PF00027.24 KEY71727.1 - 0.027 14.2 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Cupin_4 PF08007.7 KEY71727.1 - 0.056 12.6 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein HgmA PF04209.8 KEY71727.1 - 0.074 11.4 0.0 0.084 11.2 0.0 1.1 1 0 0 1 1 1 0 homogentisate 1,2-dioxygenase Cupin_7 PF12973.2 KEY71727.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 1 0 1 1 1 0 ChrR Cupin-like domain Arrestin_N PF00339.24 KEY71728.1 - 0.00077 19.2 0.0 0.0045 16.8 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Amidase PF01425.16 KEY71729.1 - 1.3e-81 274.7 0.0 7.8e-60 202.9 0.0 2.2 1 1 1 2 2 2 2 Amidase HET PF06985.6 KEY71729.1 - 5.2e-23 81.7 0.0 1.2e-22 80.5 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BPL_N PF09825.4 KEY71729.1 - 0.089 11.5 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal AAA PF00004.24 KEY71730.1 - 5.6e-17 62.1 0.0 1.1e-16 61.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEY71730.1 - 0.0013 18.4 0.0 0.0042 16.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KEY71730.1 - 0.0018 18.3 0.3 0.02 15.0 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEY71730.1 - 0.0031 17.2 0.1 0.0076 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEY71730.1 - 0.0049 16.8 0.4 0.027 14.4 0.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.1 KEY71730.1 - 0.04 13.5 0.0 0.092 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KEY71730.1 - 0.13 11.3 0.1 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PNP_UDP_1 PF01048.15 KEY71731.1 - 1.2e-14 53.8 0.4 1e-13 50.8 0.3 2.4 1 1 0 1 1 1 1 Phosphorylase superfamily HET PF06985.6 KEY71734.1 - 4.7e-21 75.3 0.7 3.1e-20 72.7 0.5 2.4 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) CFEM PF05730.6 KEY71735.1 - 3.8e-14 52.2 11.2 6.8e-14 51.4 7.7 1.4 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.15 KEY71735.1 - 0.0058 16.6 1.9 0.014 15.3 1.3 1.6 1 0 0 1 1 1 1 Gamma-thionin family Methyltransf_18 PF12847.2 KEY71735.1 - 0.15 12.6 0.0 0.29 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.13 KEY71736.1 - 6.7e-10 38.7 10.0 1.6e-09 37.5 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.6 KEY71737.1 - 1.1e-20 74.2 0.0 2.2e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 KEY71738.1 - 2.2e-33 114.4 9.0 2e-19 69.7 1.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEY71738.1 - 4.5e-26 89.3 2.2 9.3e-09 34.6 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KEY71738.1 - 4.6e-17 61.6 6.4 6.2e-12 45.3 0.3 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY71738.1 - 1.1e-16 59.2 0.3 1.3e-06 28.1 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KEY71738.1 - 1e-15 57.7 5.8 3.8e-08 33.6 1.2 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) WXG100 PF06013.7 KEY71738.1 - 0.014 15.3 1.3 0.037 14.0 0.0 2.4 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Syntaxin PF00804.20 KEY71738.1 - 0.17 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Syntaxin zf-C2H2_2 PF12756.2 KEY71740.1 - 1.2e-23 83.1 3.2 3.4e-22 78.4 1.5 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KEY71740.1 - 0.077 13.2 0.1 0.2 11.9 0.1 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Ribosomal_60s PF00428.14 KEY71740.1 - 1.5 9.2 5.3 0.37 11.2 0.7 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Lipoprotein_1 PF00820.14 KEY71741.1 - 1.2 8.1 12.5 1.2 8.0 6.6 2.1 1 1 1 2 2 2 0 Borrelia lipoprotein RNase_H2-Ydr279 PF09468.5 KEY71742.1 - 0.015 14.4 3.6 0.028 13.6 2.5 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) YcfA PF07927.7 KEY71742.1 - 0.043 13.7 0.1 0.25 11.2 0.0 2.5 2 0 0 2 2 2 0 YcfA-like protein Dynamin_N PF00350.18 KEY71743.1 - 4e-31 108.0 0.3 4.5e-30 104.6 0.0 2.5 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KEY71743.1 - 8.1e-15 54.3 0.0 1.4e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 KEY71743.1 - 3.5e-05 23.7 0.0 0.00014 21.8 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 KEY71743.1 - 0.00096 18.9 0.4 0.0025 17.6 0.3 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain Nucleoporin_FG PF13634.1 KEY71743.1 - 0.0083 16.3 21.4 0.0083 16.3 14.8 3.4 2 1 1 3 3 3 1 Nucleoporin FG repeat region AAA_23 PF13476.1 KEY71743.1 - 0.025 14.8 0.6 0.11 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KEY71743.1 - 0.029 14.8 0.7 0.16 12.4 0.1 2.4 2 1 1 3 3 3 0 Miro-like protein AAA_29 PF13555.1 KEY71743.1 - 0.065 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Abhydrolase_3 PF07859.8 KEY71744.1 - 1.9e-27 96.2 0.9 4.3e-27 95.0 0.6 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KEY71744.1 - 4e-06 25.7 0.0 5.3e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 KEY71744.1 - 0.001 19.0 4.8 0.0041 17.0 3.1 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY71744.1 - 0.0014 18.3 0.1 0.0036 17.0 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KEY71744.1 - 0.0036 17.5 0.1 0.008 16.4 0.1 1.5 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.16 KEY71744.1 - 0.045 12.9 0.0 0.52 9.4 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family MmgE_PrpD PF03972.9 KEY71745.1 - 3.8e-37 127.5 0.5 4.3e-37 127.3 0.3 1.1 1 0 0 1 1 1 1 MmgE/PrpD family adh_short PF00106.20 KEY71746.1 - 2.8e-26 92.4 0.2 3.9e-26 91.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY71746.1 - 6.1e-12 45.8 0.0 9.1e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY71746.1 - 6.6e-12 45.4 0.0 9.7e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY71746.1 - 0.001 18.5 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY71746.1 - 0.017 15.1 0.2 0.034 14.1 0.1 1.6 2 0 0 2 2 2 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KEY71746.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DYW_deaminase PF14432.1 KEY71747.1 - 1.2e-25 89.7 0.1 3.7e-25 88.1 0.0 1.9 2 0 0 2 2 2 1 DYW family of nucleic acid deaminases Ank PF00023.25 KEY71747.1 - 1.1e-20 72.3 0.0 1.1e-09 37.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 KEY71747.1 - 2.5e-17 63.0 0.0 6.3e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEY71747.1 - 3e-12 45.5 0.0 1.9e-05 24.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KEY71747.1 - 4.9e-11 42.8 0.1 1.1e-05 25.8 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY71747.1 - 5e-09 36.1 0.1 5.5e-08 32.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Gly_transf_sug PF04488.10 KEY71748.1 - 1.3e-09 38.3 0.0 2.5e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KEY71748.1 - 2.9e-08 33.2 0.1 4e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 KEY71748.1 - 0.0017 16.9 0.0 0.012 14.1 0.0 2.0 1 1 1 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain DUF4328 PF14219.1 KEY71749.1 - 0.073 12.3 0.0 0.22 10.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) Mannosyl_trans3 PF11051.3 KEY71752.1 - 0.0052 16.1 0.0 0.0087 15.4 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 KEY71752.1 - 0.099 11.9 1.2 0.7 9.1 0.9 2.2 1 1 0 1 1 1 0 Glycosyl transferase family 8 FAD_binding_3 PF01494.14 KEY71754.1 - 2e-69 234.3 0.0 4.4e-69 233.2 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KEY71754.1 - 0.046 13.5 0.0 0.54 10.0 0.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 KEY71754.1 - 0.077 11.1 0.0 0.14 10.3 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) HD PF01966.17 KEY71755.1 - 7.6e-05 22.7 0.0 0.00016 21.6 0.0 1.5 1 1 0 1 1 1 1 HD domain Med4 PF10018.4 KEY71756.1 - 0.051 12.9 0.1 0.078 12.3 0.1 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Trp_repressor PF01371.14 KEY71756.1 - 0.092 12.6 0.1 0.62 10.0 0.0 2.3 2 0 0 2 2 2 0 Trp repressor protein Abhydrolase_6 PF12697.2 KEY71758.1 - 1.8e-05 24.7 0.0 3.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KEY71758.1 - 0.0053 16.0 0.0 0.009 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF900 PF05990.7 KEY71758.1 - 0.023 14.0 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.8 KEY71758.1 - 0.046 13.3 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase PGAP1 PF07819.8 KEY71758.1 - 0.06 12.9 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein CHAT PF12770.2 KEY71759.1 - 1.4e-34 119.5 0.1 2.4e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_16 PF13432.1 KEY71759.1 - 1.6e-07 31.7 2.0 0.00014 22.4 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEY71759.1 - 1.4e-06 28.5 2.4 0.012 15.9 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEY71759.1 - 7.8e-06 26.0 2.3 0.49 11.1 0.3 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEY71759.1 - 1.7e-05 24.6 6.7 0.14 12.1 1.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEY71759.1 - 8.5e-05 22.1 4.4 0.056 13.3 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEY71759.1 - 0.00014 21.4 2.8 0.052 13.1 0.2 3.2 3 0 0 3 3 3 2 TPR repeat Apc3 PF12895.2 KEY71759.1 - 0.00038 20.5 0.5 0.23 11.6 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KEY71759.1 - 0.00046 19.7 1.8 3.6 7.6 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 KEY71759.1 - 0.021 15.2 2.9 36 5.2 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ketoacyl-synt_C PF02801.17 KEY71759.1 - 0.052 13.3 0.0 0.49 10.2 0.0 2.4 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain TPR_10 PF13374.1 KEY71759.1 - 0.13 12.2 1.7 50 4.0 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEY71759.1 - 1.8 8.5 5.9 1.1 9.1 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF385 PF04075.9 KEY71761.1 - 0.046 13.6 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF385) Ist1 PF03398.9 KEY71762.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Thr_synth_N PF14821.1 KEY71763.1 - 9.5e-29 99.2 0.0 2.2e-28 98.0 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 KEY71763.1 - 1.3e-16 60.7 0.0 9.8e-16 57.8 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme XRCC4 PF06632.7 KEY71764.1 - 0.035 12.9 1.7 0.051 12.4 1.2 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 CobT PF06213.7 KEY71764.1 - 2.1 7.3 13.9 3.1 6.8 9.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF619 PF04768.8 KEY71765.1 - 2.7e-40 137.5 0.0 8.7e-40 135.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF619) AA_kinase PF00696.23 KEY71765.1 - 1.8e-25 89.9 0.0 3.2e-23 82.5 0.0 2.7 2 1 0 2 2 2 1 Amino acid kinase family GFA PF04828.9 KEY71767.1 - 3.1e-11 43.0 0.7 8.5e-11 41.6 0.5 1.8 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Phage_GPD PF05954.6 KEY71768.1 - 0.05 12.7 0.1 0.065 12.4 0.1 1.1 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) HeLo PF14479.1 KEY71769.1 - 1.3e-37 129.6 0.1 2.2e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Glyco_tranf_2_3 PF13641.1 KEY71770.1 - 2.3e-11 43.9 0.2 1.3e-09 38.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KEY71770.1 - 2.4e-10 40.4 1.6 2.4e-10 40.4 1.1 2.3 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 KEY71770.1 - 2.6e-07 30.1 0.1 1.6e-06 27.5 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 KEY71770.1 - 5.4e-07 28.3 0.3 1e-05 24.1 0.2 2.2 1 1 0 1 1 1 1 Chitin synthase Fringe PF02434.11 KEY71771.1 - 2.2e-06 27.0 1.9 2e-05 23.9 0.8 2.4 2 1 0 2 2 2 1 Fringe-like PAN_4 PF14295.1 KEY71771.1 - 0.013 15.2 3.6 0.031 13.9 2.5 1.6 1 0 0 1 1 1 0 PAN domain DUF4585 PF15232.1 KEY71771.1 - 0.075 12.9 0.3 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) MFS_1 PF07690.11 KEY71772.1 - 3.8e-27 94.9 35.9 3.8e-27 94.9 24.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_4 PF01565.18 KEY71773.1 - 5.7e-24 84.1 0.7 1.3e-23 83.0 0.5 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY71773.1 - 2e-11 43.6 0.2 3.8e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like AA_permease PF00324.16 KEY71775.1 - 1.4e-131 439.1 50.2 1.7e-131 438.8 34.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEY71775.1 - 5.7e-34 117.3 56.5 9.1e-34 116.7 39.1 1.3 1 1 0 1 1 1 1 Amino acid permease PSDC PF12588.3 KEY71776.1 - 1.3e-54 183.6 0.0 2e-54 183.0 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 KEY71776.1 - 3e-35 121.3 0.0 4.1e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 KEY71776.1 - 0.0094 15.5 0.2 0.039 13.6 0.2 1.9 2 0 0 2 2 2 1 Biotin-lipoyl like Peptidase_M23 PF01551.17 KEY71776.1 - 0.024 14.6 0.1 0.056 13.5 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M23 Aldo_ket_red PF00248.16 KEY71777.1 - 1.6e-66 224.0 0.1 1.8e-66 223.8 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HET PF06985.6 KEY71781.1 - 1.5e-30 106.1 0.2 2.3e-30 105.5 0.2 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_M19 PF01244.16 KEY71782.1 - 6.2e-101 337.5 0.0 7.7e-101 337.2 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Tyrosinase PF00264.15 KEY71783.1 - 9.5e-37 127.2 0.5 1.2e-36 126.9 0.4 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase HMG_box PF00505.14 KEY71783.1 - 0.071 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 HMG (high mobility group) box Sugar_tr PF00083.19 KEY71786.1 - 2e-105 352.9 20.6 2.3e-105 352.8 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY71786.1 - 8.4e-26 90.5 40.4 7.1e-24 84.1 16.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 KEY71786.1 - 0.00021 20.1 0.6 0.00021 20.1 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF791) Bac_rhamnosid PF05592.6 KEY71787.1 - 5.5e-135 450.4 0.0 6.7e-135 450.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 KEY71787.1 - 3.8e-51 173.0 0.0 6.1e-51 172.3 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain DUF608 PF04685.8 KEY71787.1 - 0.0018 17.0 0.1 0.0028 16.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Fungal_trans PF04082.13 KEY71788.1 - 1.2e-06 27.6 0.0 1.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 KEY71789.1 - 3.1e-36 124.9 0.0 6.8e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 ABC_tran PF00005.22 KEY71789.1 - 3.5e-36 124.5 0.0 9.7e-18 64.7 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC2_membrane PF01061.19 KEY71789.1 - 2.1e-35 121.8 16.9 2.1e-35 121.8 11.7 2.4 3 0 0 3 3 3 1 ABC-2 type transporter PDR_CDR PF06422.7 KEY71789.1 - 5.2e-27 93.5 0.1 1.1e-25 89.2 0.0 2.5 2 0 0 2 2 2 1 CDR ABC transporter AAA_25 PF13481.1 KEY71789.1 - 2.8e-08 33.4 0.0 9.7e-05 21.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KEY71789.1 - 1e-05 25.6 0.2 0.0025 17.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KEY71789.1 - 2.5e-05 23.5 0.0 0.0023 17.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KEY71789.1 - 0.0001 22.1 0.2 1.1 9.1 0.0 3.4 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 KEY71789.1 - 0.00018 20.9 0.6 0.11 12.0 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 KEY71789.1 - 0.00049 19.2 9.9 0.00096 18.2 6.9 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_18 PF13238.1 KEY71789.1 - 0.0019 18.5 0.0 0.52 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 KEY71789.1 - 0.0028 17.0 0.0 0.0062 15.9 0.0 1.6 1 0 0 1 1 1 1 Thymidylate kinase AAA_19 PF13245.1 KEY71789.1 - 0.004 16.8 0.4 0.88 9.3 0.1 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 KEY71789.1 - 0.0044 17.1 0.0 1.3 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KEY71789.1 - 0.0047 16.9 0.0 0.39 10.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KEY71789.1 - 0.012 15.3 0.2 1.3 8.6 0.0 2.6 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.14 KEY71789.1 - 0.012 14.8 0.0 0.52 9.5 0.0 3.0 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain cobW PF02492.14 KEY71789.1 - 0.02 14.3 3.0 0.12 11.7 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 KEY71789.1 - 0.035 12.9 0.0 3.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Viral_helicase1 PF01443.13 KEY71789.1 - 0.057 12.9 0.4 24 4.3 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 KEY71789.1 - 0.1 12.2 0.0 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase AAA_23 PF13476.1 KEY71789.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KEY71789.1 - 0.13 12.8 0.0 33 4.9 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein PduV-EutP PF10662.4 KEY71789.1 - 0.18 11.2 1.2 2.4 7.6 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 KEY71789.1 - 0.19 11.2 0.2 3.2 7.1 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 KEY71789.1 - 0.2 12.4 0.0 16 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KEY71789.1 - 0.23 11.4 0.0 33 4.4 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase UPF0079 PF02367.12 KEY71789.1 - 0.23 11.0 0.7 1.8 8.2 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 KEY71789.1 - 0.28 11.3 0.2 37 4.5 0.1 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KEY71789.1 - 0.5 9.4 0.5 8.8 5.3 0.2 2.2 2 0 0 2 2 2 0 Zeta toxin p450 PF00067.17 KEY71790.1 - 1.2e-33 116.3 0.0 3.2e-31 108.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 WBP-1 PF11669.3 KEY71791.1 - 0.036 14.1 0.1 0.036 14.1 0.1 3.1 4 0 0 4 4 4 0 WW domain-binding protein 1 p450 PF00067.17 KEY71792.1 - 5e-28 97.8 0.0 2.6e-27 95.4 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KEY71793.1 - 3.4e-24 85.2 0.0 2.3e-23 82.4 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Pec_lyase_C PF00544.14 KEY71794.1 - 1.1e-21 77.2 7.4 1.8e-21 76.5 5.1 1.3 1 0 0 1 1 1 1 Pectate lyase MFS_1 PF07690.11 KEY71795.1 - 3.4e-23 81.9 32.8 7.3e-23 80.8 21.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.23 KEY71796.1 - 1.1e-79 267.8 0.0 2.2e-79 266.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KEY71796.1 - 2.2e-72 243.5 0.1 5.5e-72 242.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEY71796.1 - 7.5e-51 173.3 0.0 1.5e-50 172.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KEY71796.1 - 3.7e-49 166.8 0.0 3.7e-47 160.3 0.0 2.6 2 0 0 2 2 2 1 KR domain Condensation PF00668.15 KEY71796.1 - 2.6e-43 148.0 0.2 4.7e-43 147.1 0.1 1.4 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 KEY71796.1 - 4.7e-41 140.4 0.0 1.6e-37 129.0 0.0 2.7 2 0 0 2 2 2 2 short chain dehydrogenase PS-DH PF14765.1 KEY71796.1 - 6.4e-41 140.4 0.2 1.1e-40 139.6 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KEY71796.1 - 3.8e-31 107.4 0.1 8.5e-31 106.2 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KEY71796.1 - 4.7e-31 107.5 0.0 1e-30 106.4 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 KEY71796.1 - 4.7e-18 65.4 0.0 2e-17 63.4 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 KEY71796.1 - 2.2e-15 56.6 1.0 6.2e-07 29.5 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 KEY71796.1 - 5.2e-15 55.5 0.0 1.3e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY71796.1 - 6e-14 52.3 0.0 1.8e-13 50.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY71796.1 - 3.3e-10 39.7 0.0 8.4e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 KEY71796.1 - 2.9e-09 36.7 0.0 2e-07 30.6 0.0 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family HxxPF_rpt PF13745.1 KEY71796.1 - 4.4e-08 33.3 0.0 1.5e-07 31.6 0.0 2.0 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_18 PF12847.2 KEY71796.1 - 1.2e-07 32.2 0.0 3.9e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain AMP-binding_C PF13193.1 KEY71796.1 - 1.6e-06 28.9 3.5 1e-05 26.3 0.0 3.6 4 0 0 4 4 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 KEY71796.1 - 8.6e-06 24.6 0.0 0.0013 17.4 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.18 KEY71796.1 - 3.1e-05 23.0 0.0 5.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 KEY71796.1 - 0.00028 20.0 0.0 0.00061 18.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 KEY71796.1 - 0.011 15.2 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase NodS PF05401.6 KEY71796.1 - 0.041 13.2 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_8 PF05148.10 KEY71796.1 - 0.19 11.3 0.0 0.51 9.9 0.0 1.6 2 0 0 2 2 1 0 Hypothetical methyltransferase RrnaAD PF00398.15 KEY71796.1 - 0.3 10.0 0.0 0.58 9.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FAM70 PF14967.1 KEY71797.1 - 0.014 14.5 0.5 0.026 13.7 0.4 1.3 1 0 0 1 1 1 0 FAM70 protein p450 PF00067.17 KEY71798.1 - 3.7e-46 157.6 0.0 4.8e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NSP13 PF06460.7 KEY71798.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NSP13 ADH_zinc_N PF00107.21 KEY71799.1 - 1.1e-10 41.1 0.0 1.4e-09 37.6 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY71799.1 - 0.013 15.2 0.0 0.043 13.5 0.0 1.9 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain DUF2264 PF10022.4 KEY71800.1 - 1.4e-88 297.0 0.0 1.7e-88 296.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) V-SNARE_C PF12352.3 KEY71801.1 - 1.3e-13 50.7 1.1 7.9e-13 48.2 0.1 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KEY71801.1 - 1.6e-05 24.4 0.1 0.00013 21.6 0.0 2.1 2 1 0 2 2 2 1 Sec20 TPR_MLP1_2 PF07926.7 KEY71801.1 - 0.027 14.2 4.4 0.029 14.1 0.8 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein SPX PF03105.14 KEY71801.1 - 0.045 13.5 1.8 0.055 13.2 1.3 1.1 1 0 0 1 1 1 0 SPX domain Snf7 PF03357.16 KEY71801.1 - 0.08 12.3 1.5 0.13 11.5 0.3 1.8 2 0 0 2 2 2 0 Snf7 Filament PF00038.16 KEY71801.1 - 0.19 11.1 3.0 1.6 8.0 0.7 2.6 2 1 1 3 3 3 0 Intermediate filament protein DivIVA PF05103.8 KEY71801.1 - 0.29 11.1 3.1 3.4 7.7 0.8 2.3 2 1 0 2 2 2 0 DivIVA protein DUF4407 PF14362.1 KEY71801.1 - 0.3 10.0 5.5 0.77 8.6 3.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.10 KEY71801.1 - 0.3 10.6 5.1 13 5.3 0.0 3.1 2 2 1 3 3 3 0 Septum formation initiator PspB PF06667.7 KEY71801.1 - 0.33 10.9 3.4 0.99 9.3 2.4 1.8 1 0 0 1 1 1 0 Phage shock protein B TPK_catalytic PF04263.11 KEY71802.1 - 5e-25 87.4 0.0 6.7e-25 87.0 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 KEY71802.1 - 2.8e-21 75.0 0.1 4.1e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CHCH PF06747.8 KEY71803.1 - 3.6e-05 23.5 5.3 5.7e-05 22.9 3.6 1.3 1 0 0 1 1 1 1 CHCH domain Ribosom_S12_S23 PF00164.20 KEY71803.1 - 0.11 11.8 1.0 0.19 11.1 0.7 1.3 1 0 0 1 1 1 0 Ribosomal protein S12/S23 NPH3 PF03000.9 KEY71804.1 - 0.043 13.3 0.3 0.055 12.9 0.2 1.1 1 0 0 1 1 1 0 NPH3 family SpoIIP PF07454.6 KEY71804.1 - 0.16 11.0 2.3 0.2 10.7 1.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF1469 PF07332.6 KEY71804.1 - 0.3 10.8 2.3 0.64 9.7 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF883 PF05957.8 KEY71804.1 - 5 7.5 6.7 19 5.7 0.6 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Myb_DNA-bind_3 PF12776.2 KEY71805.1 - 2.4e-18 66.5 0.4 2.4e-18 66.5 0.3 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain NmrA PF05368.8 KEY71806.1 - 4.5e-15 55.5 0.0 4.9e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY71806.1 - 4.3e-09 36.6 0.2 7.2e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEY71806.1 - 0.0012 18.3 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KEY71806.1 - 0.0046 17.2 0.1 0.009 16.3 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KEY71806.1 - 0.062 13.7 0.5 0.15 12.4 0.4 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KEY71806.1 - 0.085 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.15 KEY71806.1 - 0.095 12.6 0.0 0.4 10.6 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Histone PF00125.19 KEY71808.1 - 6.2e-22 77.5 0.1 8.1e-22 77.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KEY71808.1 - 0.00011 22.2 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GMC_oxred_N PF00732.14 KEY71809.1 - 2.3e-53 181.2 0.0 4e-53 180.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY71809.1 - 2.2e-32 112.3 0.0 4e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Ank_2 PF12796.2 KEY71810.1 - 1.4e-52 176.0 3.6 5.5e-16 58.6 0.0 8.9 2 2 3 7 7 7 5 Ankyrin repeats (3 copies) Ank PF00023.25 KEY71810.1 - 3.6e-40 133.7 12.8 3.3e-07 29.7 0.8 13.2 14 0 0 14 14 12 7 Ankyrin repeat Ank_4 PF13637.1 KEY71810.1 - 7.2e-26 90.0 11.7 0.00025 21.4 0.1 11.3 9 4 5 14 14 12 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY71810.1 - 9e-22 76.6 13.0 1.6e-07 31.3 0.2 8.0 6 3 3 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY71810.1 - 2e-20 70.8 0.6 0.0002 21.2 0.2 10.6 12 0 0 12 12 10 2 Ankyrin repeat NACHT PF05729.7 KEY71810.1 - 2.8e-12 46.6 0.0 7.1e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain KaiC PF06745.8 KEY71810.1 - 1.1e-05 24.6 0.0 0.00012 21.2 0.0 2.3 2 0 0 2 2 2 1 KaiC Arch_ATPase PF01637.13 KEY71810.1 - 3.4e-05 23.6 0.0 7.7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase AAA PF00004.24 KEY71810.1 - 6.7e-05 23.1 0.0 0.0002 21.5 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEY71810.1 - 8.1e-05 22.6 0.0 0.00065 19.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain PNP_UDP_1 PF01048.15 KEY71810.1 - 9.9e-05 21.4 0.1 0.00017 20.6 0.1 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.1 KEY71810.1 - 0.00017 21.7 0.0 0.00064 19.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KEY71810.1 - 0.0083 16.0 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KEY71810.1 - 0.018 13.9 0.0 0.036 12.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain EntA_Immun PF08951.5 KEY71810.1 - 0.094 12.8 0.2 21 5.3 0.1 3.1 2 0 0 2 2 2 0 Enterocin A Immunity AAA_18 PF13238.1 KEY71810.1 - 0.13 12.5 0.0 0.54 10.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain Glyco_hydro_12 PF01670.11 KEY71811.1 - 7.4e-19 68.0 0.1 1.3e-18 67.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Glyco_tranf_2_3 PF13641.1 KEY71812.1 - 5.9e-34 117.8 0.0 8.5e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KEY71812.1 - 7.3e-19 68.2 0.5 7.3e-19 68.2 0.3 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.9 KEY71812.1 - 4.3e-11 41.8 4.6 4.9e-07 28.4 1.2 3.0 1 1 2 3 3 3 2 Cellulose synthase Glyco_transf_21 PF13506.1 KEY71812.1 - 1.3e-10 40.8 0.0 2.3e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KEY71812.1 - 2.9e-09 36.8 0.0 4.7e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 HATPase_c PF02518.21 KEY71813.1 - 7.5e-24 83.5 0.0 1.5e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KEY71813.1 - 4.9e-18 65.1 0.4 1.2e-17 63.9 0.1 1.8 2 0 0 2 2 2 1 Response regulator receiver domain PAS_9 PF13426.1 KEY71813.1 - 2.6e-14 53.4 0.0 2.3e-11 43.9 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 KEY71813.1 - 1.9e-09 37.5 0.0 8.8e-06 25.7 0.0 3.3 2 1 0 2 2 2 2 PAS fold HisKA PF00512.20 KEY71813.1 - 2.5e-08 33.8 0.2 5.7e-08 32.6 0.2 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 KEY71813.1 - 1.5e-07 31.2 0.0 4e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 KEY71813.1 - 5.5e-05 23.1 0.0 0.00015 21.7 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 KEY71813.1 - 0.00013 21.6 0.0 0.00045 19.9 0.0 1.9 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.1 KEY71813.1 - 0.17 11.4 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CrtC PF07143.6 KEY71814.1 - 4.4e-13 49.2 0.0 7.1e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) Sugar_tr PF00083.19 KEY71815.1 - 2.2e-95 319.8 24.1 2.5e-95 319.6 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY71815.1 - 1.3e-19 70.1 21.8 1.3e-19 70.1 15.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KEY71815.1 - 3.8e-05 22.1 1.8 3.8e-05 22.1 1.3 1.7 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 KEY71815.1 - 0.14 12.2 3.3 0.67 10.0 0.3 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1228) FAD_binding_4 PF01565.18 KEY71816.1 - 3.2e-21 75.2 2.4 7.9e-21 73.9 1.7 1.7 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY71816.1 - 0.0063 16.3 0.5 0.068 13.0 0.0 2.3 2 0 0 2 2 2 1 Berberine and berberine like Arylsulfotran_2 PF14269.1 KEY71818.1 - 2.5e-57 194.3 3.1 3.5e-57 193.8 2.1 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KEY71818.1 - 5.5e-22 77.9 2.5 9e-22 77.2 1.8 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) 7TMR-DISM_7TM PF07695.6 KEY71819.1 - 0.3 10.7 7.4 0.3 10.7 4.2 1.6 2 0 0 2 2 2 0 7TM diverse intracellular signalling Asp_protease_2 PF13650.1 KEY71820.1 - 8e-05 23.0 0.0 0.00028 21.3 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KEY71820.1 - 0.0085 15.8 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 KEY71820.1 - 0.12 12.2 0.1 0.69 9.8 0.0 2.2 3 0 0 3 3 3 0 Retroviral aspartyl protease Zn_clus PF00172.13 KEY71821.1 - 0.0041 16.9 1.4 0.0077 16.1 1.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain E1-E2_ATPase PF00122.15 KEY71823.1 - 6.3e-47 159.5 3.8 6.3e-47 159.5 2.6 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KEY71823.1 - 4.3e-25 89.4 2.2 7.9e-25 88.5 1.6 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEY71823.1 - 2.2e-14 54.0 0.0 5.1e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KEY71823.1 - 2.2e-07 30.9 0.1 1.1e-06 28.6 0.0 2.3 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 KEY71823.1 - 0.1 12.1 0.5 3.5 7.1 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Sugar_tr PF00083.19 KEY71824.1 - 1.6e-118 396.1 24.9 1.9e-118 395.9 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY71824.1 - 2.4e-21 75.8 63.3 7e-19 67.7 24.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily EBP PF05241.7 KEY71824.1 - 0.032 13.2 6.0 0.073 12.0 4.2 1.5 1 0 0 1 1 1 0 Emopamil binding protein DUF3154 PF11351.3 KEY71824.1 - 0.37 10.5 7.1 1.9 8.2 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3154) LRR19-TM PF15176.1 KEY71824.1 - 0.38 10.4 1.5 24 4.6 0.1 3.3 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain Glyco_hydro_32N PF00251.15 KEY71825.1 - 2.1e-06 27.3 4.1 2.1e-06 27.3 2.9 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain PaRep2a PF07903.6 KEY71825.1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 PaRep2a protein Glyco_transf_8 PF01501.15 KEY71826.1 - 4.2e-07 29.5 0.0 0.00061 19.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 8 zf-RING_2 PF13639.1 KEY71827.1 - 0.00011 21.9 11.0 0.00021 21.0 7.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KEY71827.1 - 0.0076 15.8 9.2 0.017 14.7 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEY71827.1 - 0.018 15.0 11.9 0.068 13.2 8.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 KEY71827.1 - 0.039 13.6 7.5 0.073 12.8 5.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 KEY71827.1 - 0.13 12.2 7.1 0.27 11.2 4.9 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 KEY71827.1 - 0.18 11.6 8.8 0.42 10.5 6.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KEY71827.1 - 0.2 11.7 6.5 0.52 10.4 4.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 KEY71827.1 - 0.92 9.2 11.5 2.1 8.0 7.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Acetyltransf_7 PF13508.1 KEY71830.1 - 3.6e-05 23.8 0.0 7.5e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEY71830.1 - 6e-05 23.1 0.4 0.0012 19.0 0.0 2.7 2 2 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEY71830.1 - 0.00012 21.9 0.0 0.00038 20.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEY71830.1 - 0.0011 18.9 0.0 0.004 17.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family WD40 PF00400.27 KEY71831.1 - 4e-10 39.1 2.5 0.0095 15.7 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF676 PF05057.9 KEY71831.1 - 1.2e-07 31.2 0.0 1.5e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KEY71831.1 - 1.7e-06 27.7 0.1 4e-06 26.6 0.1 1.6 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KEY71831.1 - 7.5e-06 25.9 0.0 1.7e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family NACHT PF05729.7 KEY71831.1 - 0.0001 21.9 0.0 0.00027 20.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEY71831.1 - 0.00085 19.3 0.0 0.0046 16.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEY71831.1 - 0.0013 18.8 0.0 0.0052 16.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain PQQ_2 PF13360.1 KEY71831.1 - 0.0028 17.1 0.0 0.011 15.2 0.0 2.1 1 0 0 1 1 1 1 PQQ-like domain Abhydrolase_5 PF12695.2 KEY71831.1 - 0.0052 16.5 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 KEY71831.1 - 0.0059 15.6 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase NTPase_1 PF03266.10 KEY71831.1 - 0.064 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 NTPase Thioesterase PF00975.15 KEY71831.1 - 0.092 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain MobB PF03205.9 KEY71831.1 - 0.11 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B HPIP PF15226.1 KEY71831.1 - 0.12 12.4 0.3 0.4 10.7 0.0 2.0 2 0 0 2 2 2 0 HCF-1 beta-propeller-interacting protein family AAA_19 PF13245.1 KEY71831.1 - 0.18 11.5 0.0 0.46 10.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Fructosamin_kin PF03881.9 KEY71832.1 - 3.9e-30 104.8 0.0 5.4e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KEY71832.1 - 4.6e-05 23.2 0.0 6.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KEY71832.1 - 0.093 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase HrpB1_HrpK PF09613.5 KEY71832.1 - 0.097 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) His_biosynth PF00977.16 KEY71834.1 - 1.2e-29 103.1 0.0 1.5e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 KEY71834.1 - 0.068 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Anillin PF08174.6 KEY71835.1 - 1e-32 113.1 0.1 3e-32 111.5 0.1 1.8 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 KEY71835.1 - 2.6e-08 34.0 0.0 8.1e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 PH domain DUF1900 PF08954.6 KEY71836.1 - 2.1e-47 160.0 0.0 2.5e-46 156.5 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 KEY71836.1 - 1.4e-34 117.5 0.0 2.8e-34 116.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 KEY71836.1 - 2.6e-25 87.2 1.0 5.2e-07 29.2 0.1 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 KEY71836.1 - 0.0043 15.2 1.0 0.64 8.0 0.0 2.4 2 1 1 3 3 3 2 Nucleoporin Nup120/160 HemX PF04375.9 KEY71836.1 - 0.0051 15.4 1.0 0.0051 15.4 0.7 1.6 2 0 0 2 2 2 1 HemX Nucleoporin_N PF08801.6 KEY71836.1 - 0.042 12.6 0.2 0.54 8.9 0.1 2.5 1 1 1 2 2 2 0 Nup133 N terminal like DUF2890 PF11081.3 KEY71836.1 - 3.6 7.6 11.2 6.8 6.7 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) TMPIT PF07851.8 KEY71836.1 - 5.2 6.0 5.1 0.82 8.6 0.3 1.8 2 0 0 2 2 2 0 TMPIT-like protein STE PF02200.11 KEY71837.1 - 1.9e-61 205.0 0.5 3.5e-61 204.1 0.2 1.6 2 0 0 2 2 2 1 STE like transcription factor zf-C2H2 PF00096.21 KEY71837.1 - 0.00023 21.2 3.8 0.00074 19.7 2.7 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY71837.1 - 0.0012 19.0 2.9 0.0028 17.8 2.0 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger DUF4602 PF15375.1 KEY71838.1 - 0.00023 21.2 1.9 0.00023 21.2 1.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4602) AF1Q PF15017.1 KEY71838.1 - 0.95 9.4 7.7 2 8.3 5.3 1.5 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator BCNT PF07572.7 KEY71839.1 - 3.7e-26 90.8 0.5 8.6e-26 89.7 0.3 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development WD40 PF00400.27 KEY71840.1 - 2e-19 68.6 18.8 9.5e-08 31.6 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS2_N PF14781.1 KEY71840.1 - 0.15 11.6 0.0 0.64 9.6 0.0 1.9 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal SNF2_N PF00176.18 KEY71841.1 - 2.4e-84 282.6 1.4 2.4e-84 282.6 0.9 2.6 3 0 0 3 3 3 1 SNF2 family N-terminal domain Bromodomain PF00439.20 KEY71841.1 - 1.1e-20 73.3 0.3 3.1e-20 71.8 0.2 1.8 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 KEY71841.1 - 1.2e-18 67.0 1.2 1.2e-18 67.0 0.8 4.3 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex Helicase_C PF00271.26 KEY71841.1 - 2.1e-16 59.5 0.0 2.1e-16 59.5 0.0 3.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.8 KEY71841.1 - 7.4e-13 48.0 13.9 7.4e-13 48.0 9.7 4.0 3 0 0 3 3 3 1 HSA Abhydrolase_6 PF12697.2 KEY71842.1 - 3e-06 27.3 0.1 0.012 15.4 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family PGAP1 PF07819.8 KEY71842.1 - 0.00033 20.3 0.1 0.001 18.7 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KEY71842.1 - 0.00038 20.2 0.3 0.0013 18.4 0.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KEY71842.1 - 0.027 13.7 0.0 0.049 12.9 0.0 1.5 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Pex14_N PF04695.8 KEY71842.1 - 0.19 11.7 1.4 0.47 10.5 1.0 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PTPLA PF04387.9 KEY71843.1 - 1.9e-53 180.2 11.6 3.3e-53 179.4 8.0 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DIOX_N PF14226.1 KEY71844.1 - 1.9e-21 76.7 0.0 3.3e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KEY71844.1 - 1.3e-18 67.0 0.0 2.1e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidohydro_2 PF04909.9 KEY71845.1 - 1.5e-44 152.6 0.1 1.8e-44 152.3 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 KEY71845.1 - 0.0027 16.9 0.0 0.01 15.0 0.0 1.9 2 1 0 2 2 2 1 TatD related DNase DnaJ PF00226.26 KEY71846.1 - 1.8e-12 46.8 7.2 1.9e-12 46.7 0.0 3.5 4 0 0 4 4 4 1 DnaJ domain OmpH PF03938.9 KEY71846.1 - 0.017 15.0 0.4 0.017 15.0 0.3 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) FAM75 PF14650.1 KEY71846.1 - 1.5 8.1 3.8 2 7.7 2.6 1.2 1 0 0 1 1 1 0 FAM75 family Ycf1 PF05758.7 KEY71846.1 - 8.6 3.9 8.4 9.4 3.7 5.8 1.1 1 0 0 1 1 1 0 Ycf1 DUF2235 PF09994.4 KEY71847.1 - 1.4e-68 231.2 0.0 1.9e-68 230.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KEY71847.1 - 0.048 13.4 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family GCV_T PF01571.16 KEY71848.1 - 5.8e-12 45.4 0.0 2e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KEY71848.1 - 0.0024 17.8 0.0 0.0077 16.2 0.0 2.0 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain Nop25 PF09805.4 KEY71849.1 - 0.022 14.8 3.6 0.04 13.9 2.5 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF605 PF04652.11 KEY71849.1 - 0.061 12.7 6.6 0.064 12.6 4.6 1.1 1 0 0 1 1 1 0 Vta1 like BUD22 PF09073.5 KEY71849.1 - 0.21 10.5 9.1 0.24 10.4 6.3 1.1 1 0 0 1 1 1 0 BUD22 DEAD PF00270.24 KEY71850.1 - 5e-42 143.2 0.0 1.2e-40 138.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY71850.1 - 6e-27 93.3 0.1 1.6e-26 91.9 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KEY71850.1 - 1.5e-06 27.2 0.0 2.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KEY71850.1 - 0.0017 18.2 0.0 0.0049 16.7 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Pkinase PF00069.20 KEY71851.1 - 1.8e-59 201.0 0.0 2.2e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY71851.1 - 2.2e-35 121.9 0.0 3e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY71851.1 - 2.9e-07 29.7 0.0 4.3e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like TruD PF01142.13 KEY71852.1 - 1.1e-52 178.9 0.0 1.2e-48 165.7 0.0 3.6 3 1 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) SAD_SRA PF02182.12 KEY71853.1 - 4e-05 22.9 0.0 0.00011 21.5 0.0 1.7 2 0 0 2 2 2 1 SAD/SRA domain Rotamase_3 PF13616.1 KEY71854.1 - 2.6e-19 69.6 0.7 5.1e-19 68.6 0.0 1.7 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase PF00639.16 KEY71854.1 - 5.3e-17 62.3 0.0 5.3e-17 62.3 0.0 1.6 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KEY71854.1 - 1.8e-06 28.6 0.8 4.2e-06 27.3 0.0 1.7 1 1 1 2 2 2 1 PPIC-type PPIASE domain Ribosomal_L7Ae PF01248.21 KEY71855.1 - 9.3e-29 98.7 1.0 1.2e-28 98.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 KEY71855.1 - 0.069 12.7 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Ribosomal_S8 PF00410.14 KEY71856.1 - 1.8e-23 82.7 0.0 3.1e-22 78.8 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein S8 Glyco_transf_90 PF05686.7 KEY71857.1 - 1.5e-16 60.1 10.3 1.4e-12 46.9 5.5 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 Paf1 PF03985.8 KEY71858.1 - 1.5e-54 185.4 1.2 2.4e-54 184.7 0.9 1.3 1 1 0 1 1 1 1 Paf1 ASC PF00858.19 KEY71858.1 - 0.016 13.8 0.0 0.018 13.7 0.0 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel Rer1 PF03248.8 KEY71859.1 - 3.7e-79 264.4 9.8 4.2e-79 264.2 6.8 1.0 1 0 0 1 1 1 1 Rer1 family ECH PF00378.15 KEY71860.1 - 4.5e-70 235.5 0.1 5.5e-70 235.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KEY71860.1 - 0.054 13.2 0.1 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Peptidase family S49 DUF2828 PF11443.3 KEY71860.1 - 0.11 10.7 0.0 0.15 10.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PALP PF00291.20 KEY71861.1 - 1.5e-61 208.2 0.1 2.1e-61 207.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-RING_2 PF13639.1 KEY71861.1 - 8.3e-07 28.7 5.4 8.3e-07 28.7 3.7 4.8 4 1 1 5 5 4 1 Ring finger domain zf-C3HC4 PF00097.20 KEY71861.1 - 8.7e-07 28.4 4.8 8.7e-07 28.4 3.3 5.2 5 1 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KEY71861.1 - 1.6e-05 24.5 0.6 1.6e-05 24.5 0.4 4.0 4 0 0 4 4 3 1 zf-RING of BARD1-type protein SH3_9 PF14604.1 KEY71861.1 - 0.0001 21.8 0.1 0.00029 20.3 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain zf-C3HC4_2 PF13923.1 KEY71861.1 - 0.00011 22.1 5.1 0.00011 22.1 3.5 5.3 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY71861.1 - 0.0002 20.9 3.9 0.0002 20.9 2.7 5.5 5 1 0 5 5 5 1 zinc-RING finger domain SH3_1 PF00018.23 KEY71861.1 - 0.00027 20.2 0.0 0.00062 19.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain zf-C3HC4_4 PF15227.1 KEY71861.1 - 0.00095 18.9 4.0 0.00095 18.9 2.8 4.3 5 1 0 5 5 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KEY71861.1 - 0.006 16.2 2.2 0.017 14.8 1.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger DUF3292 PF11696.3 KEY71861.1 - 0.73 7.6 0.9 1.2 6.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) ComZ PF10815.3 KEY71862.1 - 0.0038 16.9 0.3 0.044 13.5 0.1 2.8 3 1 0 3 3 3 1 ComZ Chlam_PMP PF02415.12 KEY71862.1 - 0.065 13.5 0.2 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Ribosomal_L19 PF01245.15 KEY71863.1 - 1e-16 60.7 0.0 1.7e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 CH PF00307.26 KEY71864.1 - 2.6e-39 133.6 0.3 1.4e-19 70.1 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 KEY71864.1 - 2.8e-28 97.6 1.3 1.1e-27 95.7 0.1 2.6 3 0 0 3 3 3 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 KEY71864.1 - 1.2e-13 50.5 0.5 5.9e-08 32.2 0.0 3.3 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 KEY71864.1 - 0.0066 16.2 0.3 0.14 12.1 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 KEY71864.1 - 0.025 14.2 2.5 0.48 10.0 0.1 3.0 1 1 1 2 2 2 0 EF-hand domain pair DAG_kinase_N PF14513.1 KEY71864.1 - 0.026 14.7 0.1 0.15 12.2 0.1 2.3 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus EF-hand_7 PF13499.1 KEY71864.1 - 0.18 11.9 1.6 0.92 9.6 1.1 2.3 1 0 0 1 1 1 0 EF-hand domain pair FAD-oxidase_C PF02913.14 KEY71865.1 - 1.4e-55 188.3 0.0 2.1e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KEY71865.1 - 9e-37 125.6 0.3 1.7e-36 124.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.13 KEY71866.1 - 7.9e-07 28.8 12.8 1.7e-06 27.7 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.21 KEY71867.1 - 1e-53 181.4 0.1 1.4e-53 181.0 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEY71867.1 - 1.8e-12 46.3 0.1 1.8e-12 46.3 0.1 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Glyco_hydro_66 PF13199.1 KEY71867.1 - 0.1 10.9 0.1 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 zf-CHY PF05495.7 KEY71868.1 - 6.9e-14 51.7 19.6 9.1e-14 51.3 13.6 1.1 1 0 0 1 1 1 1 CHY zinc finger Tmemb_55A PF09788.4 KEY71868.1 - 0.023 13.8 7.0 0.026 13.6 4.9 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A Zn-ribbon_8 PF09723.5 KEY71868.1 - 0.3 11.0 13.2 1.3 9.0 6.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_3 PF14369.1 KEY71868.1 - 0.87 9.6 10.6 1.1 9.2 4.8 2.5 1 1 1 2 2 2 0 zinc-finger Zn_Tnp_IS1595 PF12760.2 KEY71868.1 - 1 9.2 12.6 14 5.6 5.9 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DUF3797 PF12677.2 KEY71868.1 - 1.3 8.7 0.0 1.3 8.7 0.0 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF3797) Cytochrome_C7 PF14522.1 KEY71868.1 - 1.3 8.7 14.5 2 8.1 10.0 1.4 1 0 0 1 1 1 0 Cytochrome c7 C1_4 PF07975.7 KEY71868.1 - 1.7 8.7 16.5 2.4 8.2 5.7 2.6 1 1 2 3 3 3 0 TFIIH C1-like domain HypA PF01155.14 KEY71868.1 - 3.1 7.5 12.3 21 4.8 8.5 2.2 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Evr1_Alr PF04777.8 KEY71868.1 - 3.2 7.7 12.9 45 4.0 8.9 2.7 1 1 0 1 1 1 0 Erv1 / Alr family Helicase_C_3 PF13625.1 KEY71869.1 - 1.9e-26 92.3 0.0 3.9e-25 88.0 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEY71869.1 - 5.4e-14 52.4 0.0 1.5e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KEY71869.1 - 1.8e-10 40.5 0.0 4.1e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KEY71869.1 - 3.1e-09 36.0 0.0 5.1e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain TrkH PF02386.11 KEY71871.1 - 1.7e-117 391.9 14.2 1.8e-117 391.9 5.9 2.1 2 0 0 2 2 2 2 Cation transport protein VPS9 PF02204.13 KEY71872.1 - 7.5e-24 83.7 0.0 1.4e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain AMP-binding PF00501.23 KEY71873.1 - 1.7e-68 230.9 0.0 2.1e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEY71873.1 - 3.1e-17 63.2 0.1 6.2e-17 62.3 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Phage_Mu_Gp45 PF06890.7 KEY71873.1 - 0.13 11.6 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage Mu Gp45 protein Aldo_ket_red PF00248.16 KEY71874.1 - 2.3e-47 161.1 0.0 2.8e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family GFA PF04828.9 KEY71875.1 - 0.00038 20.3 0.0 0.00072 19.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Glyco_hydro_1 PF00232.13 KEY71876.1 - 2.9e-151 503.7 0.0 3.5e-151 503.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF4137 PF13593.1 KEY71877.1 - 1.5e-83 280.4 22.1 1.8e-83 280.2 15.3 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Erf4 PF10256.4 KEY71878.1 - 2.9e-29 101.3 0.0 4.2e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Claudin_2 PF13903.1 KEY71879.1 - 0.0095 15.6 0.0 0.29 10.8 0.0 2.3 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction IncA PF04156.9 KEY71879.1 - 0.039 13.5 5.8 0.031 13.8 2.3 2.0 2 0 0 2 2 2 0 IncA protein Barttin PF15462.1 KEY71879.1 - 0.093 12.3 1.0 0.26 10.9 0.7 1.7 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) CCDC-167 PF15188.1 KEY71879.1 - 0.094 12.6 3.0 0.48 10.3 2.1 2.1 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 OmpH PF03938.9 KEY71879.1 - 0.27 11.1 6.8 0.51 10.2 4.7 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4510 PF14971.1 KEY71879.1 - 1.2 9.3 9.4 5.4 7.1 6.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4510) DUF4203 PF13886.1 KEY71880.1 - 5.5e-35 120.7 25.1 7e-35 120.3 17.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) STE3 PF02076.10 KEY71881.1 - 7.4e-36 123.6 14.2 1.1e-35 123.0 9.9 1.3 1 0 0 1 1 1 1 Pheromone A receptor SSB PF00436.20 KEY71882.1 - 5.2e-18 64.8 0.0 6.3e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family GSH_synth_ATP PF03917.12 KEY71883.1 - 1.1e-111 373.0 0.0 1.3e-111 372.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KEY71883.1 - 4.5e-32 110.2 0.0 8.3e-32 109.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DUF1364 PF07102.7 KEY71883.1 - 0.04 13.7 0.3 0.078 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) SNF2_N PF00176.18 KEY71884.1 - 1.3e-47 162.0 0.0 2.4e-47 161.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEY71884.1 - 4.6e-16 58.4 0.3 1.1e-15 57.2 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TPR_12 PF13424.1 KEY71885.1 - 0.00066 19.5 0.1 0.0026 17.6 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 KEY71885.1 - 0.0014 18.4 5.2 0.3 11.0 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 KEY71886.1 - 3.4e-19 68.7 0.3 2.5e-18 65.8 0.2 2.2 1 1 0 1 1 1 1 Phosphorylase superfamily NUP PF06516.6 KEY71886.1 - 0.00072 18.4 0.0 0.031 13.0 0.0 2.3 2 0 0 2 2 2 2 Purine nucleoside permease (NUP) Glyco_trans_4_4 PF13579.1 KEY71886.1 - 0.47 10.5 3.2 0.57 10.3 0.9 2.1 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain bZIP_1 PF00170.16 KEY71887.1 - 9.2e-05 22.3 4.2 0.00019 21.3 2.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KEY71887.1 - 0.0014 18.3 3.4 0.0014 18.3 2.3 1.9 3 0 0 3 3 3 1 Basic region leucine zipper SRP-alpha_N PF04086.8 KEY71887.1 - 0.065 12.6 6.7 0.09 12.1 4.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal U79_P34 PF03064.11 KEY71887.1 - 0.42 10.0 8.6 0.55 9.7 6.0 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF1880 PF08976.6 KEY71887.1 - 0.92 9.6 5.0 22 5.1 1.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1880) Methyltransf_4 PF02390.12 KEY71887.1 - 1 8.3 3.5 1.6 7.7 2.4 1.2 1 0 0 1 1 1 0 Putative methyltransferase DUF2413 PF10310.4 KEY71887.1 - 2.1 7.0 8.5 2.5 6.7 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF566 PF04484.7 KEY71887.1 - 4.1 6.8 12.9 5.2 6.4 8.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Striatin PF08232.7 KEY71887.1 - 9.8 6.4 9.5 16 5.7 6.5 1.4 1 1 0 1 1 1 0 Striatin family DNA_ligase_A_M PF01068.16 KEY71888.1 - 1.4e-21 76.8 0.0 2.3e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain Abhydrolase_3 PF07859.8 KEY71889.1 - 1.4e-29 103.1 0.5 1.7e-29 102.9 0.3 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KEY71889.1 - 2.6e-10 39.6 0.0 6.2e-10 38.4 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KEY71889.1 - 0.00012 21.9 0.1 0.00024 20.8 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY71889.1 - 0.00022 21.2 2.0 0.00031 20.7 1.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KEY71889.1 - 0.0039 16.5 0.0 0.0054 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Chlorophyllase2 PF12740.2 KEY71889.1 - 0.0081 15.0 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 KEY71889.1 - 0.037 13.2 0.1 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family PGAP1 PF07819.8 KEY71889.1 - 0.077 12.5 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase PF07224.6 KEY71889.1 - 0.15 10.7 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase Chromo PF00385.19 KEY71890.1 - 0.011 15.4 0.1 5.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_C48 PF02902.14 KEY71892.1 - 2.5e-05 24.0 0.2 7e-05 22.5 0.1 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain bZIP_1 PF00170.16 KEY71893.1 - 4.7e-06 26.4 6.4 4.7e-06 26.4 4.4 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KEY71893.1 - 0.0012 18.5 7.7 0.0023 17.7 5.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper GST_C_3 PF14497.1 KEY71893.1 - 0.013 15.9 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain p450 PF00067.17 KEY71896.1 - 3e-45 154.6 0.0 4e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 KEY71897.1 - 0.091 12.6 5.9 0.19 11.6 4.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PKD PF00801.15 KEY71898.1 - 0.079 12.7 0.3 0.46 10.2 0.0 2.1 2 0 0 2 2 2 0 PKD domain HET PF06985.6 KEY71899.1 - 1.4e-08 34.9 5.3 2.9e-08 33.9 1.3 2.5 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) peroxidase PF00141.18 KEY71901.1 - 1e-27 97.0 0.0 1.7e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Gly_transf_sug PF04488.10 KEY71902.1 - 1.7e-05 25.1 0.0 3.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif HET PF06985.6 KEY71904.1 - 4.5e-21 75.4 6.6 1.1e-17 64.4 4.6 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 KEY71904.1 - 5.9e-13 48.9 0.4 1.2e-10 41.5 0.1 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEY71904.1 - 6.4e-08 32.9 0.2 1.9e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY71904.1 - 3.4e-07 29.8 0.5 7e-05 22.6 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 KEY71904.1 - 3.7e-07 29.6 3.0 1.4e-05 24.6 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 KEY71904.1 - 3e-06 27.2 0.1 1.9e-05 24.7 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) vWA-TerF-like PF10138.4 KEY71904.1 - 0.094 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus COesterase PF00135.23 KEY71905.1 - 1.2e-64 218.9 0.0 1.6e-64 218.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEY71905.1 - 1.2e-06 28.2 0.1 4.4e-06 26.4 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold AAA_16 PF13191.1 KEY71906.1 - 1.6e-07 31.4 0.7 1.2e-05 25.3 0.0 3.8 4 1 1 5 5 5 1 AAA ATPase domain NACHT PF05729.7 KEY71906.1 - 2.8e-07 30.3 0.0 1.2e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KEY71906.1 - 2.2e-05 24.6 0.0 0.00019 21.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Ank_2 PF12796.2 KEY71906.1 - 0.0021 18.3 0.7 0.48 10.7 0.0 3.6 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) KAP_NTPase PF07693.9 KEY71906.1 - 0.0048 15.9 0.4 0.73 8.7 0.1 3.1 4 0 0 4 4 4 1 KAP family P-loop domain Arch_ATPase PF01637.13 KEY71906.1 - 0.0092 15.7 0.1 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase Ank_3 PF13606.1 KEY71906.1 - 0.027 14.7 0.1 2.3 8.7 0.0 3.9 3 0 0 3 3 3 0 Ankyrin repeat RNA_helicase PF00910.17 KEY71906.1 - 0.074 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Ank PF00023.25 KEY71906.1 - 0.099 12.4 3.2 15 5.6 0.0 4.8 6 1 0 6 6 6 0 Ankyrin repeat Viral_helicase1 PF01443.13 KEY71906.1 - 0.15 11.5 0.0 0.43 10.0 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase KR PF08659.5 KEY71907.1 - 2e-25 89.5 0.2 6.6e-25 87.8 0.0 1.8 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KEY71907.1 - 3.2e-15 56.4 0.0 5.7e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 KEY71907.1 - 0.016 15.4 0.1 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Phosphopantetheine attachment site Rotavirus_VP1 PF12289.3 KEY71907.1 - 0.018 14.6 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 Rotavirus VP1 structural protein Fungal_trans PF04082.13 KEY71908.1 - 7e-14 51.3 0.0 1.2e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3328 PF11807.3 KEY71909.1 - 6.5e-21 75.0 0.4 2.1e-17 63.5 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3328) DUF3328 PF11807.3 KEY71910.1 - 0.00023 20.9 0.0 0.0003 20.5 0.0 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Fungal_trans PF04082.13 KEY71911.1 - 1.9e-08 33.5 0.0 2.6e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_12 PF13424.1 KEY71911.1 - 0.0097 15.8 0.1 0.03 14.2 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEY71911.1 - 0.12 12.2 0.1 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEY71911.1 - 0.13 11.9 0.1 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3328 PF11807.3 KEY71912.1 - 6.4e-22 78.3 4.4 1.3e-21 77.3 3.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) PsbI PF02532.9 KEY71913.1 - 0.84 9.3 3.0 1.6 8.3 2.1 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) adh_short PF00106.20 KEY71914.1 - 1.4e-20 73.9 3.5 1.8e-20 73.5 2.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY71914.1 - 6.8e-16 58.4 0.4 9.6e-16 57.9 0.3 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY71914.1 - 3.9e-11 43.1 0.0 4.8e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 KEY71914.1 - 9.1e-07 28.0 0.0 1.2e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KEY71914.1 - 0.00015 21.2 1.3 0.00066 19.1 0.9 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family MFS_1 PF07690.11 KEY71915.1 - 1.8e-37 128.9 19.8 1.8e-37 128.9 13.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily CBM_6 PF03422.10 KEY71916.1 - 1.2e-08 35.2 0.2 2.5e-08 34.1 0.1 1.5 1 1 1 2 2 2 1 Carbohydrate binding module (family 6) Esterase_phd PF10503.4 KEY71917.1 - 3.7e-05 23.0 0.6 0.00025 20.3 0.1 2.1 1 1 2 3 3 3 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KEY71917.1 - 3.8e-05 23.0 0.3 6.9e-05 22.1 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEY71917.1 - 4.1e-05 23.3 0.1 5.2e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KEY71917.1 - 0.00011 21.7 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KEY71917.1 - 0.00076 19.4 0.5 0.0021 17.9 0.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KEY71917.1 - 0.067 12.5 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 KEY71917.1 - 0.081 11.4 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase PF00756.15 KEY71917.1 - 0.11 11.8 0.1 0.19 11.1 0.1 1.5 1 1 0 1 1 1 0 Putative esterase RTA1 PF04479.8 KEY71918.1 - 2.5e-40 138.3 0.7 3.8e-40 137.7 0.5 1.2 1 0 0 1 1 1 1 RTA1 like protein Myb_DNA-binding PF00249.26 KEY71919.1 - 9.1e-32 108.8 7.5 1.3e-11 44.4 0.1 3.8 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEY71919.1 - 1.4e-31 108.3 3.9 1.6e-15 56.9 0.1 3.6 2 1 1 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 KEY71919.1 - 0.021 14.9 6.1 0.39 10.9 0.2 3.0 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.3 KEY71919.1 - 0.027 14.3 7.4 2 8.3 1.6 3.3 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_5 PF13873.1 KEY71919.1 - 0.088 12.7 7.8 29 4.6 0.8 5.2 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain p450 PF00067.17 KEY71920.1 - 2.6e-57 194.3 0.0 2e-56 191.4 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 KEY71921.1 - 1.3e-79 267.2 0.0 2.1e-79 266.6 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEY71921.1 - 5.9e-56 190.1 0.0 9.2e-54 182.9 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KEY71921.1 - 2.9e-34 117.4 0.1 9e-34 115.8 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 KEY71921.1 - 7.4e-23 81.9 0.1 2e-22 80.5 0.0 1.7 2 0 0 2 2 1 1 Thioesterase domain PP-binding PF00550.20 KEY71921.1 - 7.6e-20 70.9 0.7 2.6e-10 40.4 0.0 3.2 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 KEY71921.1 - 1.2e-19 70.6 0.0 2.8e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_5 PF12695.2 KEY71921.1 - 8.6e-07 28.8 0.5 0.0019 17.9 0.1 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY71921.1 - 1e-06 28.8 1.8 9.1e-06 25.7 0.0 3.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 KEY71921.1 - 0.0039 16.2 0.0 0.0094 14.9 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF2974 PF11187.3 KEY71921.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.8 KEY71921.1 - 0.018 14.6 0.1 0.04 13.4 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEY71921.1 - 0.022 13.9 0.2 0.04 13.1 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PGAP1 PF07819.8 KEY71921.1 - 0.043 13.4 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.15 KEY71921.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Delta_lysin PF05372.6 KEY71921.1 - 0.12 11.7 0.0 0.36 10.2 0.0 1.8 1 0 0 1 1 1 0 Delta lysin family AMP-binding PF00501.23 KEY71922.1 - 1.3e-36 125.8 0.0 8.7e-36 123.1 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KEY71922.1 - 3.9e-17 62.0 0.0 8.3e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KEY71922.1 - 7e-05 22.3 0.2 0.0064 15.9 0.0 3.2 2 1 1 3 3 3 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KEY71922.1 - 0.0004 20.5 0.0 0.0013 18.9 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site PTR2 PF00854.16 KEY71923.1 - 1.2e-36 126.3 11.5 1.2e-36 126.3 8.0 2.7 2 1 0 2 2 2 1 POT family MFS_1 PF07690.11 KEY71923.1 - 2e-07 30.0 18.3 2e-07 30.0 12.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily ERG2_Sigma1R PF04622.7 KEY71924.1 - 1.6e-95 318.4 0.1 1.8e-95 318.2 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein NPCC PF08058.6 KEY71926.1 - 8.6e-28 96.9 0.0 7.2e-27 94.0 0.0 1.9 1 1 0 1 1 1 1 Nuclear pore complex component DUF2975 PF11188.3 KEY71926.1 - 0.12 12.0 0.5 0.18 11.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DUF410 PF04190.8 KEY71927.1 - 2.4e-48 164.9 0.0 2.8e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) UPF0220 PF05255.6 KEY71928.1 - 3.9e-61 205.1 2.8 5.1e-61 204.7 1.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) eIF-3c_N PF05470.7 KEY71929.1 - 0.029 12.4 0.0 0.033 12.2 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Tim54 PF11711.3 KEY71929.1 - 0.048 12.2 1.6 0.082 11.4 1.1 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF1510 PF07423.6 KEY71929.1 - 0.06 12.7 7.6 0.086 12.1 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Mem_trans PF03547.13 KEY71929.1 - 0.75 8.0 9.3 1.2 7.4 6.3 1.3 1 1 0 1 1 1 0 Membrane transport protein ABC_membrane PF00664.18 KEY71930.1 - 4.4e-48 164.0 35.8 8.2e-29 100.8 11.5 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 KEY71930.1 - 1.1e-46 158.5 0.0 4.2e-27 95.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KEY71930.1 - 3.3e-06 27.2 2.6 1.2 9.0 0.1 4.9 3 2 0 4 4 4 1 AAA domain SMC_N PF02463.14 KEY71930.1 - 2.1e-05 23.8 0.7 0.99 8.5 0.2 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KEY71930.1 - 3.1e-05 23.8 1.8 0.17 11.8 0.2 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 KEY71930.1 - 4e-05 24.0 1.1 0.16 12.4 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 KEY71930.1 - 8.9e-05 21.9 2.1 0.12 11.9 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KEY71930.1 - 0.00011 22.2 0.8 0.042 13.8 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KEY71930.1 - 0.00011 22.9 1.1 0.25 12.1 0.4 3.3 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 KEY71930.1 - 0.00094 18.0 1.3 0.43 9.3 0.0 2.3 2 0 0 2 2 2 2 ArgK protein AAA_22 PF13401.1 KEY71930.1 - 0.0015 18.6 0.7 1.9 8.6 0.0 3.3 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KEY71930.1 - 0.0018 17.3 0.1 0.91 8.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_10 PF12846.2 KEY71930.1 - 0.0019 17.7 0.3 0.97 8.7 0.1 2.5 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 KEY71930.1 - 0.0031 16.9 0.1 0.69 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KEY71930.1 - 0.0034 17.7 0.9 5.2 7.3 0.1 3.1 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.12 KEY71930.1 - 0.0036 17.1 3.3 0.2 11.4 0.6 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 DUF258 PF03193.11 KEY71930.1 - 0.005 16.0 1.7 0.86 8.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DUF106 PF01956.11 KEY71930.1 - 0.0077 15.7 0.6 0.24 10.9 0.3 2.8 2 1 0 2 2 2 1 Integral membrane protein DUF106 AAA_30 PF13604.1 KEY71930.1 - 0.0093 15.5 0.8 3.8 7.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 KEY71930.1 - 0.022 13.3 0.8 1.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 KEY71930.1 - 0.03 13.2 0.4 0.59 8.9 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.18 KEY71930.1 - 0.031 14.0 5.8 0.07 12.9 0.1 2.9 3 0 0 3 3 3 0 Dynamin family AAA_18 PF13238.1 KEY71930.1 - 0.039 14.2 1.8 1.6 9.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KEY71930.1 - 0.062 12.9 1.1 5.3 6.7 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KEY71930.1 - 0.11 11.9 2.1 5.1 6.5 0.0 2.7 3 0 0 3 3 2 0 FtsK/SpoIIIE family NACHT PF05729.7 KEY71930.1 - 0.14 11.8 0.2 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.12 KEY71930.1 - 0.23 10.9 3.5 14 5.1 0.1 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 KEY71930.1 - 0.66 9.9 2.7 0.64 9.9 0.0 2.3 3 0 0 3 3 2 0 AAA domain Halogen_Hydrol PF10112.4 KEY71930.1 - 7.6 5.8 6.1 8.9 5.6 0.5 2.7 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein EXOSC1 PF10447.4 KEY71931.1 - 1.6e-25 88.8 2.5 2.4e-25 88.3 1.7 1.2 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 KEY71931.1 - 3e-10 39.2 2.1 4.2e-10 38.7 1.1 1.6 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 KEY71931.1 - 0.018 15.1 1.1 0.2 11.7 0.8 2.3 1 1 0 1 1 1 0 S1 RNA binding domain Sec2p PF06428.6 KEY71932.1 - 3e-08 33.4 19.3 8.7e-08 31.9 11.2 2.4 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p FUSC PF04632.7 KEY71932.1 - 0.3 9.4 17.1 0.52 8.6 1.0 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF2360 PF10152.4 KEY71932.1 - 0.43 10.8 13.6 0.6 10.3 3.9 2.8 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) IncA PF04156.9 KEY71932.1 - 0.77 9.3 20.8 10 5.6 0.0 2.6 2 1 1 3 3 3 0 IncA protein V_ATPase_I PF01496.14 KEY71932.1 - 1.1 6.9 9.9 26 2.4 0.0 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family MbeD_MobD PF04899.7 KEY71932.1 - 1.6 8.7 5.8 4.8 7.1 1.1 2.7 2 1 0 2 2 2 0 MbeD/MobD like Atg14 PF10186.4 KEY71932.1 - 3.9 6.3 12.7 72 2.1 9.1 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 BTV_NS2 PF04514.7 KEY71932.1 - 6.2 5.5 13.0 9.1 5.0 9.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 EMP24_GP25L PF01105.19 KEY71932.1 - 9.7 5.8 5.9 7.5 6.2 0.0 2.4 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD TruB_N PF01509.13 KEY71933.1 - 2.3e-45 154.3 0.0 6.1e-45 153.0 0.0 1.7 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) Glyco_hydro_62 PF03664.8 KEY71934.1 - 5.8e-145 481.4 11.1 6.6e-145 481.2 7.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 DNMT1-RFD PF12047.3 KEY71935.1 - 0.049 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain SOG2 PF10428.4 KEY71935.1 - 1.9 7.0 6.3 0.35 9.4 0.8 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein MIF4G_like PF09088.6 KEY71936.1 - 1.9e-78 262.2 0.0 3e-78 261.6 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 KEY71936.1 - 4.9e-47 160.2 0.0 6.7e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 KEY71936.1 - 0.18 11.1 0.0 0.55 9.5 0.0 1.8 2 0 0 2 2 2 0 MIF4G domain Pkinase PF00069.20 KEY71937.1 - 7.4e-58 195.7 0.0 2e-57 194.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY71937.1 - 6.1e-21 74.6 0.0 1.2e-20 73.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY71937.1 - 1.6e-05 24.0 0.0 5.9e-05 22.1 0.0 1.8 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 KEY71937.1 - 0.0034 17.1 0.1 0.01 15.5 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEY71937.1 - 0.081 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Methyltransf_23 PF13489.1 KEY71939.1 - 4.6e-18 65.4 0.0 6.1e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY71939.1 - 6.4e-13 49.0 0.0 2.7e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY71939.1 - 1.4e-12 47.9 0.0 2.2e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY71939.1 - 2.1e-12 47.5 0.0 3.9e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY71939.1 - 8.2e-12 44.9 0.0 1.4e-11 44.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY71939.1 - 1e-06 28.0 0.0 1.9e-06 27.1 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEY71939.1 - 1.1e-06 28.8 0.0 2.2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY71939.1 - 4.2e-05 23.5 0.1 0.00012 22.0 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain DUF938 PF06080.7 KEY71939.1 - 0.00078 19.0 0.0 0.0014 18.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF938) tRNA_U5-meth_tr PF05958.6 KEY71939.1 - 0.0013 17.4 0.0 0.0017 17.1 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase DREV PF05219.7 KEY71939.1 - 0.0021 17.0 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.15 KEY71939.1 - 0.0044 16.0 0.0 0.0065 15.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 KEY71939.1 - 0.0066 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 KEY71939.1 - 0.0074 15.8 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 KEY71939.1 - 0.01 15.2 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain TehB PF03848.9 KEY71939.1 - 0.025 13.7 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB CMAS PF02353.15 KEY71939.1 - 0.044 12.8 0.0 0.05 12.6 0.0 1.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase TPMT PF05724.6 KEY71939.1 - 0.097 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DUF706 PF05153.10 KEY71940.1 - 2.7e-124 413.4 0.1 3.5e-124 413.1 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) DUF837 PF05769.6 KEY71940.1 - 0.2 11.1 1.1 0.29 10.6 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF837) Fungal_trans_2 PF11951.3 KEY71941.1 - 4.3e-07 28.8 3.0 4.3e-07 28.8 2.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY71942.1 - 1.8e-09 37.3 10.9 1.8e-09 37.3 7.5 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KEY71943.1 - 3.5e-49 167.5 0.0 4.6e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ferritin_2 PF13668.1 KEY71945.1 - 4.5e-45 152.9 1.5 4.5e-45 152.9 1.1 1.6 2 0 0 2 2 2 1 Ferritin-like domain FAD_binding_4 PF01565.18 KEY71946.1 - 7.8e-18 64.2 1.1 1.4e-17 63.4 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY71946.1 - 0.011 15.6 0.1 0.032 14.1 0.0 1.9 1 0 0 1 1 1 0 Berberine and berberine like Myb_DNA-binding PF00249.26 KEY71948.1 - 4e-31 106.8 5.2 4.3e-13 49.0 0.0 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEY71948.1 - 5.8e-29 99.9 2.5 1.1e-11 44.6 0.1 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 KEY71948.1 - 0.0028 17.7 5.0 3.2 7.9 0.1 3.3 3 0 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_2 PF08914.6 KEY71948.1 - 0.0046 16.7 1.2 0.31 10.8 0.0 3.4 2 2 1 3 3 3 1 Rap1 Myb domain Rap1_C PF11626.3 KEY71948.1 - 0.15 11.9 3.3 44 4.0 2.3 3.3 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain FAD_binding_3 PF01494.14 KEY71949.1 - 9.1e-33 113.7 0.2 1.2e-31 110.0 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEY71949.1 - 2.4e-11 43.1 2.6 1.2e-06 27.6 0.4 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KEY71949.1 - 2.2e-06 27.0 0.5 0.027 13.5 0.1 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KEY71949.1 - 9e-06 25.6 0.9 2.2e-05 24.4 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KEY71949.1 - 1.1e-05 25.7 0.2 0.00014 22.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY71949.1 - 1.8e-05 24.8 0.1 5.9e-05 23.2 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEY71949.1 - 0.00014 20.4 0.1 0.0023 16.4 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 KEY71949.1 - 0.00028 20.8 0.6 0.00074 19.4 0.4 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY71949.1 - 0.00028 19.9 0.1 0.13 11.1 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.12 KEY71949.1 - 0.0004 19.5 0.1 0.00076 18.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family TrkA_N PF02254.13 KEY71949.1 - 0.0011 18.9 0.0 0.0039 17.1 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain FAD_oxidored PF12831.2 KEY71949.1 - 0.0019 17.3 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEY71949.1 - 0.0029 16.4 0.3 0.0073 15.2 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 KEY71949.1 - 0.005 17.0 0.0 0.0087 16.2 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 KEY71949.1 - 0.014 14.9 0.1 0.023 14.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 KEY71949.1 - 0.024 13.2 0.0 0.039 12.5 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase 3HCDH_N PF02737.13 KEY71949.1 - 0.032 13.8 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KEY71949.1 - 0.055 12.8 0.1 0.087 12.2 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 KEY71949.1 - 0.055 12.3 0.2 0.086 11.6 0.2 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KEY71949.1 - 0.094 12.4 0.3 1.5 8.5 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.11 KEY71949.1 - 0.1 12.0 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.20 KEY71950.1 - 1.1e-11 44.9 0.0 2.7e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY71950.1 - 2.8e-05 23.9 0.0 4.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY71950.1 - 0.00012 21.7 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KEY71950.1 - 0.00015 21.8 0.0 0.00026 21.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KEY71950.1 - 0.0033 17.4 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 KEY71950.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.17 KEY71951.1 - 6.5e-38 130.4 0.0 8.5e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Arylsulfotrans PF05935.6 KEY71952.1 - 2.2e-19 69.3 0.0 2.8e-08 32.7 0.0 3.2 1 1 2 3 3 3 3 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.1 KEY71952.1 - 4.2e-14 52.4 0.0 9.2e-14 51.2 0.0 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ_2 PF13360.1 KEY71952.1 - 0.0017 17.8 0.0 0.017 14.5 0.0 2.6 2 1 0 2 2 2 1 PQQ-like domain MFS_1 PF07690.11 KEY71953.1 - 1.2e-33 116.3 29.4 1.8e-33 115.7 20.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.13 KEY71954.1 - 2.2e-05 24.2 8.0 4.4e-05 23.2 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2360 PF10152.4 KEY71954.1 - 0.099 12.9 0.0 0.3 11.3 0.0 1.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Amidase PF01425.16 KEY71955.1 - 1.9e-37 129.2 0.0 1.1e-34 120.1 0.0 2.1 2 0 0 2 2 2 2 Amidase Lipase_GDSL PF00657.17 KEY71956.1 - 8e-17 61.8 0.2 1.1e-16 61.3 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase GFO_IDH_MocA PF01408.17 KEY71958.1 - 3.6e-20 72.6 0.1 6.5e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KEY71958.1 - 0.077 12.7 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain FAD_binding_4 PF01565.18 KEY71961.1 - 1.8e-22 79.2 7.7 1.8e-22 79.2 5.3 2.1 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.7 KEY71961.1 - 3e-15 55.8 0.0 6.2e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 KEY71963.1 - 3.6e-17 62.1 1.9 6.3e-17 61.3 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY71963.1 - 0.0078 16.1 0.5 0.017 14.9 0.3 1.6 1 0 0 1 1 1 1 Berberine and berberine like Epimerase PF01370.16 KEY71964.1 - 1.6e-06 27.7 0.0 0.0044 16.4 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KEY71964.1 - 7.9e-06 26.1 0.1 1.7e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KEY71964.1 - 0.00048 18.9 0.0 0.0035 16.0 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KEY71964.1 - 0.063 12.1 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KEY71964.1 - 0.069 12.0 0.0 0.23 10.3 0.0 1.9 1 1 1 2 2 2 0 Male sterility protein NmrA PF05368.8 KEY71964.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family p450 PF00067.17 KEY71965.1 - 2.8e-37 128.3 0.9 3.3e-37 128.1 0.6 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1426 PF07234.6 KEY71965.1 - 0.12 12.1 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) Transferase PF02458.10 KEY71966.1 - 5.1e-08 31.7 0.1 5.1e-07 28.4 0.0 2.1 1 1 0 1 1 1 1 Transferase family Pkinase_Tyr PF07714.12 KEY71967.1 - 6.6e-09 35.2 0.0 9.3e-09 34.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KEY71967.1 - 5.6e-07 28.9 0.0 7e-07 28.6 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain WaaY PF06176.6 KEY71967.1 - 0.021 14.0 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 KEY71967.1 - 0.17 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family CBM_1 PF00734.13 KEY71968.1 - 1.4e-13 50.2 8.7 4.4e-13 48.6 6.0 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain AXE1 PF05448.7 KEY71968.1 - 0.0019 16.7 0.0 0.0029 16.1 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF3809 PF12723.2 KEY71968.1 - 0.11 12.3 0.1 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3809) Glyco_hydro_11 PF00457.12 KEY71969.1 - 3.4e-71 238.4 19.5 4e-71 238.1 13.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Abhydrolase_6 PF12697.2 KEY71970.1 - 3.9e-07 30.1 0.9 2.7e-06 27.4 0.7 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family NACHT PF05729.7 KEY71970.1 - 5e-06 26.2 1.6 0.056 13.1 0.1 2.7 2 0 0 2 2 2 2 NACHT domain Abhydrolase_5 PF12695.2 KEY71970.1 - 9.8e-06 25.3 0.0 2.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_16 PF13191.1 KEY71970.1 - 0.00052 20.0 0.3 0.0039 17.1 0.0 2.5 2 1 0 3 3 3 1 AAA ATPase domain PGAP1 PF07819.8 KEY71970.1 - 0.00064 19.3 0.0 0.0018 17.9 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein AAA_25 PF13481.1 KEY71970.1 - 0.0015 18.0 1.2 0.0039 16.6 0.2 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEY71970.1 - 0.0082 16.2 0.0 0.038 14.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 KEY71970.1 - 0.019 14.1 1.1 0.24 10.5 0.8 2.3 1 1 0 1 1 1 0 KaiC DUF676 PF05057.9 KEY71970.1 - 0.027 13.7 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PIF1 PF05970.9 KEY71970.1 - 0.05 12.5 0.0 0.098 11.5 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Gemini_mov PF01708.11 KEY71971.1 - 0.014 14.8 1.1 0.025 14.1 0.8 1.4 1 0 0 1 1 1 0 Geminivirus putative movement protein MFS_1 PF07690.11 KEY71973.1 - 9.5e-29 100.2 35.3 7.1e-27 94.0 20.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY71973.1 - 0.00041 19.0 18.3 0.00062 18.4 12.7 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 KEY71973.1 - 0.0011 17.1 4.5 0.0082 14.2 2.4 2.2 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.8 KEY71973.1 - 0.36 8.9 11.9 0.008 14.4 3.1 1.9 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF4396 PF14342.1 KEY71974.1 - 1.2e-42 145.2 3.4 1.6e-42 144.9 2.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) Arrestin_N PF00339.24 KEY71975.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain uDENN PF03456.13 KEY71976.1 - 0.17 11.8 0.3 0.59 10.1 0.2 1.8 1 1 0 1 1 1 0 uDENN domain EspF PF04806.7 KEY71977.1 - 0.051 13.7 2.2 0.064 13.4 1.5 1.3 1 0 0 1 1 1 0 EspF protein repeat WD40 PF00400.27 KEY71978.1 - 4.8e-127 409.8 45.1 4.6e-14 51.6 0.2 10.0 10 0 0 10 10 10 9 WD domain, G-beta repeat HET PF06985.6 KEY71978.1 - 6.5e-20 71.7 10.3 6.7e-18 65.1 0.4 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 KEY71978.1 - 2.7e-18 66.1 0.0 5e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Cytochrom_D1 PF02239.11 KEY71978.1 - 1.4e-10 39.9 3.9 0.042 12.1 0.0 4.5 1 1 5 6 6 6 6 Cytochrome D1 heme domain Nup160 PF11715.3 KEY71978.1 - 2e-10 39.4 12.0 1.8 6.5 0.0 8.6 1 1 8 9 9 9 6 Nucleoporin Nup120/160 DUF1797 PF08796.5 KEY71978.1 - 0.0041 16.9 0.0 2e+02 1.9 0.0 5.6 6 0 0 6 6 6 0 Protein of unknown function (DUF1797) AAA_19 PF13245.1 KEY71978.1 - 0.13 12.0 0.0 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Recep_L_domain PF01030.19 KEY71981.1 - 0.00063 19.6 11.9 0.23 11.4 2.0 4.4 1 1 2 3 3 3 1 Receptor L domain LRR_5 PF13306.1 KEY71981.1 - 0.026 14.2 1.5 0.068 12.8 0.2 2.2 2 0 0 2 2 2 0 Leucine rich repeats (6 copies) DUF4098 PF13345.1 KEY71981.1 - 0.38 10.7 14.6 0.32 10.9 3.2 4.6 4 1 0 4 4 4 0 Domain of unknown function (DUF4098) G-patch PF01585.18 KEY71982.1 - 1.9e-13 49.9 1.3 3.4e-13 49.1 0.0 2.1 2 0 0 2 2 2 1 G-patch domain RRM_5 PF13893.1 KEY71982.1 - 1.3e-07 31.3 0.1 2.5e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEY71982.1 - 1.4e-05 24.5 0.1 2.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY71982.1 - 0.003 17.4 0.0 0.0061 16.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.24 KEY71983.1 - 3.6e-32 111.1 0.0 1.2e-31 109.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY71983.1 - 4.2e-22 77.8 0.0 8.2e-22 76.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KEY71983.1 - 0.00054 19.6 0.3 0.024 14.3 0.0 2.8 2 1 1 3 3 3 1 Part of AAA domain Helicase_C_2 PF13307.1 KEY71983.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain CMS1 PF14617.1 KEY71983.1 - 0.024 13.7 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 KEY71983.1 - 0.04 14.0 0.9 1 9.4 0.5 2.8 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KEY71983.1 - 0.072 12.6 0.0 0.2 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 KEY71983.1 - 0.079 12.7 0.0 0.97 9.2 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Y_phosphatase PF00102.22 KEY71983.1 - 0.18 11.0 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ribosomal_L22e PF01776.12 KEY71985.1 - 1.1e-46 157.3 0.7 1.4e-46 157.0 0.5 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Mito_carr PF00153.22 KEY71986.1 - 2.3e-55 184.2 0.1 2.3e-19 68.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4448 PF14610.1 KEY71988.1 - 0.036 13.5 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Pox_A9 PF04835.7 KEY71988.1 - 0.047 13.5 0.1 0.065 13.1 0.1 1.1 1 0 0 1 1 1 0 A9 protein conserved region TMEM154 PF15102.1 KEY71988.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family CcmH PF03918.9 KEY71988.1 - 0.1 11.6 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Transport_MerF PF11431.3 KEY71988.1 - 0.11 12.1 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Membrane transport protein MerF WBP-1 PF11669.3 KEY71988.1 - 0.12 12.4 0.1 0.25 11.4 0.1 1.5 1 1 0 1 1 1 0 WW domain-binding protein 1 RCR PF12273.3 KEY71988.1 - 2.7 8.5 13.8 2.5 8.6 6.5 2.0 1 1 1 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Tbf5 PF06331.7 KEY71989.1 - 2e-27 94.7 1.2 2.2e-27 94.6 0.8 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF1325 PF07039.6 KEY71989.1 - 0.1 12.2 0.7 0.11 12.0 0.5 1.1 1 0 0 1 1 1 0 SGF29 tudor-like domain ECH PF00378.15 KEY71990.1 - 4.6e-37 127.4 0.1 7.5e-37 126.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF2188 PF09954.4 KEY71990.1 - 0.1 12.5 0.3 0.21 11.5 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) Glyco_hydro_72 PF03198.9 KEY71991.1 - 3.9e-122 407.1 2.4 5e-122 406.7 1.7 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KEY71991.1 - 3.2e-07 29.8 0.8 9.3e-06 25.0 0.5 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Oxysterol_BP PF01237.13 KEY71992.1 - 1.1e-105 353.0 0.0 2.5e-105 351.8 0.0 1.6 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 KEY71992.1 - 8.6e-38 128.2 1.1 3.7e-37 126.2 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 KEY71992.1 - 6.2e-05 23.1 0.1 0.0011 19.1 0.0 2.8 3 0 0 3 3 3 1 PH domain GOLD_2 PF13897.1 KEY71992.1 - 0.013 15.7 1.1 0.029 14.6 0.0 2.1 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking PH_11 PF15413.1 KEY71992.1 - 0.027 14.7 1.4 1.3 9.2 1.0 2.7 1 1 0 1 1 1 0 Pleckstrin homology domain ArfGap PF01412.13 KEY71993.1 - 1.1e-38 131.5 1.8 2.1e-38 130.6 1.3 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.26 KEY71993.1 - 0.0015 18.2 0.1 0.0042 16.9 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain PSCyt3 PF07627.6 KEY71993.1 - 0.17 11.7 3.0 1.2 9.0 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1588) ODC_AZ PF02100.12 KEY71994.1 - 8.9e-26 89.5 0.0 1.4e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme His_biosynth PF00977.16 KEY71995.1 - 1.7e-49 168.1 0.7 8.7e-49 165.8 0.5 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 KEY71995.1 - 3.3e-27 95.1 0.0 5.5e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 KEY71995.1 - 3.4e-08 33.3 0.0 4.7e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 KEY71995.1 - 5.8e-07 29.2 0.1 1.4e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.12 KEY71995.1 - 0.011 14.6 0.0 0.028 13.2 0.0 1.6 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.8 KEY71995.1 - 0.02 14.3 0.3 0.65 9.4 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 TFIIIC_sub6 PF10419.4 KEY71996.1 - 9.1e-12 44.2 0.0 1.6e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit DUF946 PF06101.6 KEY71997.1 - 5.6e-13 47.7 0.3 9.4e-13 46.9 0.2 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) SH3BP5 PF05276.9 KEY71998.1 - 0.091 12.0 0.2 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) Mnd1 PF03962.10 KEY71998.1 - 0.23 11.0 0.2 0.46 10.1 0.2 1.4 1 0 0 1 1 1 0 Mnd1 family Ribosomal_L16 PF00252.13 KEY72001.1 - 6.1e-32 110.1 0.1 8.1e-32 109.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L7Ae PF01248.21 KEY72002.1 - 3.4e-24 84.1 0.0 3.9e-24 83.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3450 PF11932.3 KEY72003.1 - 0.047 12.9 17.9 0.27 10.4 9.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) CotJB PF12652.2 KEY72003.1 - 0.86 9.7 4.5 2.1 8.4 0.5 2.6 1 1 1 2 2 2 0 CotJB protein V_ATPase_I PF01496.14 KEY72003.1 - 1.4 6.6 18.1 0.21 9.4 9.1 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.11 KEY72003.1 - 1.6 7.2 10.0 2.2 6.7 7.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Adenylsucc_synt PF00709.16 KEY72003.1 - 1.8 7.1 5.1 3.5 6.1 3.5 1.4 1 0 0 1 1 1 0 Adenylosuccinate synthetase DIT1_PvcA PF05141.7 KEY72003.1 - 3.9 6.7 8.2 7 5.8 5.7 1.3 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein HAUS6_N PF14661.1 KEY72003.1 - 5.3 6.3 21.2 35 3.6 14.7 2.3 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus SPX PF03105.14 KEY72003.1 - 6.4 6.4 27.2 0.03 14.1 12.1 2.0 2 1 0 2 2 2 0 SPX domain Vac7 PF12751.2 KEY72004.1 - 8.5e-124 413.3 3.3 8.5e-124 413.3 2.3 2.1 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 RrnaAD PF00398.15 KEY72005.1 - 1.4e-57 194.7 0.0 1.8e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KEY72005.1 - 3.8e-10 39.8 0.0 8.2e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY72005.1 - 1.1e-05 25.9 0.0 2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY72005.1 - 0.00017 21.0 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KEY72005.1 - 0.00026 20.7 0.0 0.0017 18.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 KEY72005.1 - 0.00073 18.6 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 KEY72005.1 - 0.0012 18.4 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KEY72005.1 - 0.0016 17.6 0.0 0.0036 16.5 0.0 1.6 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.14 KEY72005.1 - 0.0025 17.3 0.0 0.0043 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 KEY72005.1 - 0.0041 17.5 0.0 0.013 15.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY72005.1 - 0.031 14.6 0.0 0.091 13.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.13 KEY72005.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PRP1_N PF06424.7 KEY72006.1 - 8.6e-50 168.5 8.5 1.9e-49 167.3 5.9 1.6 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 KEY72006.1 - 4.3e-32 107.6 38.3 0.0004 20.7 0.1 14.6 4 3 10 14 14 14 11 Tetratricopeptide repeat TPR_19 PF14559.1 KEY72006.1 - 1.1e-26 92.8 19.6 4.4e-07 30.1 0.2 9.8 6 3 2 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.1 KEY72006.1 - 5.2e-26 90.6 19.5 1.4e-05 25.6 0.2 8.5 7 1 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 KEY72006.1 - 2.9e-14 52.4 17.8 0.0061 16.1 0.1 8.9 6 3 4 10 10 10 4 TPR repeat TPR_2 PF07719.12 KEY72006.1 - 4.6e-12 44.8 15.3 0.01 15.6 0.0 9.7 10 1 1 11 11 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEY72006.1 - 3.5e-10 39.2 9.6 0.53 10.6 0.0 9.7 11 1 1 12 12 10 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEY72006.1 - 1.7e-08 33.6 0.0 0.0032 17.1 0.0 6.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEY72006.1 - 2.8e-06 26.7 0.7 0.78 9.6 0.0 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEY72006.1 - 2.9e-06 26.6 1.2 0.056 13.0 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.3 KEY72006.1 - 1.9e-05 23.6 8.0 0.56 8.9 0.0 5.7 5 1 2 7 7 7 3 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 KEY72006.1 - 4.7e-05 23.5 10.4 13 6.5 0.0 8.7 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_15 PF13429.1 KEY72006.1 - 0.00048 19.2 24.1 0.086 11.8 3.0 6.1 3 1 3 6 6 6 3 Tetratricopeptide repeat Suf PF05843.9 KEY72006.1 - 0.00061 19.6 0.3 9.1 5.9 0.0 4.2 3 1 1 4 4 4 0 Suppressor of forked protein (Suf) TPR_9 PF13371.1 KEY72006.1 - 0.00098 18.9 8.2 0.011 15.5 0.1 5.2 6 1 0 6 6 6 1 Tetratricopeptide repeat DUF3808 PF10300.4 KEY72006.1 - 0.0044 15.6 0.6 4.7 5.6 0.0 3.7 3 1 1 4 4 4 1 Protein of unknown function (DUF3808) TPR_12 PF13424.1 KEY72006.1 - 0.01 15.7 12.5 0.65 9.9 0.0 6.2 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_21 PF09976.4 KEY72006.1 - 0.076 12.9 24.1 0.15 12.0 0.2 5.3 5 2 2 7 7 6 0 Tetratricopeptide repeat NRDE-2 PF08424.5 KEY72006.1 - 5.2 5.8 32.2 0.015 14.1 1.1 6.3 4 2 3 7 7 7 0 NRDE-2, necessary for RNA interference Apolipoprotein PF01442.13 KEY72007.1 - 0.011 15.2 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Decorin_bind PF02352.10 KEY72007.1 - 0.024 14.6 1.4 0.031 14.2 1.0 1.2 1 0 0 1 1 1 0 Decorin binding protein MRFAP1 PF15155.1 KEY72007.1 - 3.1 8.1 5.0 3.7 7.8 1.0 1.9 1 1 1 2 2 2 0 MORF4 family-associated protein1 V-ATPase_G PF03179.10 KEY72007.1 - 3.8 7.8 8.6 9.5 6.5 3.1 2.3 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF883 PF05957.8 KEY72007.1 - 6.4 7.2 9.3 0.23 11.8 2.2 1.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4575 PF15143.1 KEY72008.1 - 0.66 9.6 5.8 0.88 9.2 2.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4575) DUF4476 PF14771.1 KEY72009.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) PP2C PF00481.16 KEY72010.1 - 4.6e-84 281.7 0.0 7.9e-84 281.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KEY72010.1 - 0.00046 19.6 0.0 0.00086 18.7 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KEY72010.1 - 0.012 15.2 0.0 0.16 11.6 0.0 2.1 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) He_PIG PF05345.7 KEY72011.1 - 9.2e-14 51.1 8.4 0.0019 18.1 0.5 4.2 3 0 0 3 3 3 3 Putative Ig domain DUF4448 PF14610.1 KEY72011.1 - 0.066 12.6 0.0 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Hum_adeno_E3A PF05393.6 KEY72011.1 - 0.41 10.3 0.8 1.3 8.7 0.6 1.8 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Methyltransf_16 PF10294.4 KEY72012.1 - 8.6e-46 155.5 0.0 1.1e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 KEY72012.1 - 0.00016 21.2 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY72012.1 - 0.00053 20.5 0.0 0.00076 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY72012.1 - 0.0016 17.8 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KEY72012.1 - 0.038 14.0 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KEY72012.1 - 0.15 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DPBB_1 PF03330.13 KEY72013.1 - 0.013 15.4 0.1 0.029 14.3 0.0 1.7 1 1 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF3681 PF12442.3 KEY72013.1 - 0.12 12.5 0.1 0.29 11.3 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3681) DUF1712 PF08217.6 KEY72014.1 - 1.2e-12 46.9 0.0 1.2e-11 43.6 0.0 2.4 2 1 0 2 2 2 1 Fungal domain of unknown function (DUF1712) CorA PF01544.13 KEY72015.1 - 0.0011 18.0 2.7 0.0027 16.7 1.9 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PspB PF06667.7 KEY72015.1 - 0.0052 16.6 0.2 0.013 15.4 0.2 1.6 1 0 0 1 1 1 1 Phage shock protein B HTH_Tnp_IS630 PF01710.11 KEY72015.1 - 0.0054 16.3 0.4 3.1 7.4 0.0 2.6 2 0 0 2 2 2 2 Transposase Kelch_3 PF13415.1 KEY72016.1 - 1.5e-18 66.4 22.8 6.5e-09 35.7 0.3 7.5 8 1 0 8 8 8 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KEY72016.1 - 2e-18 65.7 1.3 5.8e-06 26.2 0.0 4.6 4 1 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 KEY72016.1 - 3.3e-18 65.2 5.6 0.00013 21.8 0.0 6.9 7 0 0 7 7 7 4 Kelch motif Kelch_4 PF13418.1 KEY72016.1 - 6.6e-16 57.8 23.3 2.5e-05 23.9 0.0 8.6 8 1 0 8 8 8 4 Galactose oxidase, central domain Kelch_1 PF01344.20 KEY72016.1 - 4.6e-14 51.6 0.3 1.6e-05 24.2 0.1 5.0 5 1 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 KEY72016.1 - 1.9e-10 40.1 3.6 6.4e-05 22.5 0.0 5.3 6 0 0 6 6 6 2 Kelch motif DUF4643 PF15485.1 KEY72016.1 - 0.077 12.4 2.4 0.12 11.8 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) 2Fe-2S_thioredx PF01257.14 KEY72017.1 - 4.5e-57 191.7 0.0 5.6e-57 191.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin AMP-binding PF00501.23 KEY72018.1 - 6.1e-75 252.1 0.0 8.7e-75 251.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEY72018.1 - 0.039 14.8 0.8 0.18 12.7 0.0 2.7 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain DAO PF01266.19 KEY72019.1 - 4.6e-47 160.6 11.6 5.5e-47 160.3 8.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEY72019.1 - 0.00017 21.6 0.1 0.095 12.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEY72019.1 - 0.00021 20.2 0.3 0.00028 19.8 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KEY72019.1 - 0.00072 19.5 0.1 0.002 18.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KEY72019.1 - 0.00087 18.4 0.7 0.0014 17.7 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KEY72019.1 - 0.002 18.0 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEY72019.1 - 0.0028 16.8 0.0 0.0063 15.6 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KEY72019.1 - 0.025 13.0 1.0 0.043 12.3 0.4 1.5 2 0 0 2 2 2 0 HI0933-like protein Pkinase PF00069.20 KEY72020.1 - 7.4e-45 153.1 0.0 2.9e-44 151.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY72020.1 - 1.7e-25 89.5 0.0 3.2e-25 88.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY72020.1 - 0.1 11.5 0.0 0.3 9.9 0.0 1.7 2 0 0 2 2 2 0 Kinase-like dCMP_cyt_deam_1 PF00383.17 KEY72021.1 - 2.3e-25 88.2 1.1 3.6e-25 87.5 0.8 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 KEY72021.1 - 0.001 19.8 0.1 0.0029 18.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEY72021.1 - 0.002 18.4 0.0 0.037 14.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain CoaE PF01121.15 KEY72021.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase ThiF PF00899.16 KEY72022.1 - 5.8e-28 97.4 0.0 8.8e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 KEY72022.1 - 0.0026 17.8 0.0 0.041 13.9 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pmp3 PF01679.12 KEY72023.1 - 4.9e-27 93.3 5.5 5.4e-27 93.2 3.8 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.7 KEY72023.1 - 0.065 12.9 2.4 0.065 12.9 1.7 1.7 2 0 0 2 2 2 0 Conserved TM helix PIG-F PF06699.6 KEY72024.1 - 2.8e-51 174.1 2.6 3.5e-51 173.8 1.8 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Ecm33 PF12454.3 KEY72024.1 - 0.42 10.5 3.3 1.4 8.8 2.3 1.9 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Bacteriocin_IIc PF10439.4 KEY72024.1 - 0.86 9.7 4.3 0.45 10.6 1.1 1.9 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.1 KEY72024.1 - 6.5 6.4 7.5 1.2 8.8 1.9 2.1 2 0 0 2 2 2 0 Glycine zipper MFS_1 PF07690.11 KEY72026.1 - 6.4e-33 113.9 26.5 6.4e-33 113.9 18.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily SNF2_N PF00176.18 KEY72027.1 - 1.5e-52 178.2 0.1 2.6e-52 177.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 KEY72027.1 - 6.8e-23 80.3 0.6 6.8e-23 80.3 0.4 2.2 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 KEY72027.1 - 1.4e-14 53.6 0.0 4.5e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEY72027.1 - 0.00047 19.6 0.0 0.0013 18.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KEY72027.1 - 0.06 13.1 0.0 0.06 13.1 0.0 3.5 5 1 0 5 5 5 0 Type III restriction enzyme, res subunit Ribosomal_S4 PF00163.14 KEY72028.1 - 6.6e-12 45.6 2.7 1.2e-11 44.7 1.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KEY72028.1 - 3.2e-11 42.4 0.1 1.1e-10 40.8 0.0 1.8 2 0 0 2 2 2 1 S4 domain RED_C PF07807.6 KEY72028.1 - 0.039 14.1 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 RED-like protein C-terminal region Ribosomal_S18 PF01084.15 KEY72029.1 - 5e-12 45.5 0.1 9.4e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 PPR_3 PF13812.1 KEY72030.1 - 8.4e-08 31.9 3.3 1.3 9.5 0.0 7.7 7 0 0 7 7 7 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 KEY72030.1 - 1.3e-07 31.4 0.2 1.2 9.1 0.0 5.7 7 0 0 7 7 7 3 PPR repeat family PPR PF01535.15 KEY72030.1 - 0.004 17.0 1.7 26 5.0 0.0 5.5 6 0 0 6 6 6 1 PPR repeat TPR_14 PF13428.1 KEY72030.1 - 0.028 15.0 1.6 0.41 11.4 1.1 3.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Aldo_ket_red PF00248.16 KEY72031.1 - 7.7e-47 159.4 0.0 2.6e-32 111.7 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family EamA PF00892.15 KEY72032.1 - 3e-10 40.2 28.1 2.4e-06 27.6 1.5 2.6 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KEY72032.1 - 0.0023 18.1 9.3 0.0023 18.1 6.5 3.9 3 2 1 4 4 4 1 Multidrug resistance efflux transporter DUF1673 PF07895.6 KEY72032.1 - 0.65 9.4 5.6 1.3 8.4 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) TPT PF03151.11 KEY72032.1 - 1 9.0 25.0 0.26 10.9 7.5 3.2 3 1 0 3 3 3 0 Triose-phosphate Transporter family F-box-like PF12937.2 KEY72033.1 - 6.7e-07 28.9 10.9 8.3e-06 25.4 2.8 4.4 4 1 0 4 4 4 1 F-box-like F-box PF00646.28 KEY72033.1 - 0.018 14.7 9.7 0.52 10.0 0.0 4.0 3 1 0 3 3 3 0 F-box domain Methyltransf_2 PF00891.13 KEY72034.1 - 2.3e-28 98.9 0.0 3.4e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KEY72034.1 - 0.0011 18.7 0.0 0.0033 17.1 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Dimerisation PF08100.6 KEY72034.1 - 0.005 16.6 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 Dimerisation domain Rrf2 PF02082.15 KEY72034.1 - 0.03 14.4 0.0 0.078 13.1 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator Endotoxin_N PF03945.9 KEY72034.1 - 0.077 12.3 0.5 0.16 11.3 0.3 1.5 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain Methyltransf_2 PF00891.13 KEY72036.1 - 4.3e-35 121.0 0.1 6.2e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Sigma70_r4 PF04545.11 KEY72036.1 - 0.0013 18.0 0.0 0.0041 16.3 0.0 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_IclR PF09339.5 KEY72036.1 - 0.0018 17.8 0.1 0.0051 16.3 0.1 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain Methyltransf_18 PF12847.2 KEY72036.1 - 0.0035 17.9 0.1 0.024 15.2 0.0 2.4 3 1 0 3 3 3 1 Methyltransferase domain HTH_24 PF13412.1 KEY72036.1 - 0.0061 15.9 0.0 0.013 14.8 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.1 KEY72036.1 - 0.0083 15.2 0.1 0.018 14.2 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.1 KEY72036.1 - 0.018 14.6 0.0 0.77 9.4 0.0 2.6 2 0 0 2 2 2 0 Homeodomain-like domain HTH_AsnC-type PF13404.1 KEY72036.1 - 0.023 14.2 0.1 0.063 12.8 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_28 PF13518.1 KEY72036.1 - 0.035 14.1 0.0 0.64 10.0 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2805 PF10985.3 KEY72036.1 - 0.096 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) p450 PF00067.17 KEY72037.1 - 3.1e-26 91.9 0.0 3.8e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 KEY72038.1 - 3e-61 207.0 0.0 4.1e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 KEY72038.1 - 1.1e-28 100.9 0.1 2.2e-28 100.0 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 KEY72038.1 - 1.8e-09 37.7 0.2 5.4e-09 36.1 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 KEY72038.1 - 2.2e-05 24.4 0.0 5.3e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY72038.1 - 0.0043 16.6 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY72038.1 - 0.033 13.9 0.0 0.085 12.6 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family GH3 PF03321.8 KEY72038.1 - 0.22 10.0 0.0 1.9 6.9 0.0 1.9 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Cerato-platanin PF07249.7 KEY72040.1 - 2.4e-54 182.4 0.6 2.8e-54 182.2 0.4 1.0 1 0 0 1 1 1 1 Cerato-platanin GHMP_kinases_N PF00288.21 KEY72041.1 - 6.2e-13 48.6 0.0 1.5e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KEY72041.1 - 8.2e-07 29.1 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal 4HBT_2 PF13279.1 KEY72042.1 - 5.9e-05 23.5 0.0 9.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily CFEM PF05730.6 KEY72043.1 - 4.3e-10 39.2 8.6 6.8e-10 38.6 6.0 1.3 1 0 0 1 1 1 1 CFEM domain MRI PF15325.1 KEY72043.1 - 0.91 10.5 4.0 1.4 9.8 2.8 1.4 1 0 0 1 1 1 0 Modulator of retrovirus infection WD40 PF00400.27 KEY72044.1 - 1e-27 94.9 14.6 1e-07 31.5 0.2 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF2415 PF10313.4 KEY72044.1 - 0.94 9.2 2.6 1.8 8.3 0.0 2.7 3 1 1 4 4 4 0 Uncharacterised protein domain (DUF2415) Glyco_transf_8 PF01501.15 KEY72046.1 - 2.3e-22 79.5 0.0 3.6e-22 78.9 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 8 ATG2_CAD PF13329.1 KEY72047.1 - 1.8e-48 164.0 0.3 3.6e-48 163.1 0.2 1.5 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 KEY72047.1 - 1.5e-24 85.9 0.4 3.2e-23 81.7 0.0 3.5 4 0 0 4 4 4 1 ATG C terminal domain Amino_oxidase PF01593.19 KEY72048.1 - 1.4e-49 169.3 0.2 1.2e-48 166.2 0.2 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KEY72048.1 - 3.4e-14 52.6 0.1 6.9e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEY72048.1 - 1.8e-07 31.4 0.0 1.2e-05 25.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY72048.1 - 5.8e-07 29.8 1.2 5.6e-06 26.6 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEY72048.1 - 6.5e-07 28.5 0.0 1.2e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEY72048.1 - 4.7e-06 25.7 0.0 7.9e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KEY72048.1 - 3.6e-05 23.7 0.1 8.2e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEY72048.1 - 0.0002 19.9 0.4 0.00033 19.2 0.0 1.4 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KEY72048.1 - 0.0015 17.6 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KEY72048.1 - 0.0035 16.4 0.1 0.0058 15.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 KEY72048.1 - 0.004 16.8 0.1 0.0068 16.0 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KEY72048.1 - 0.0052 16.1 0.1 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.1 KEY72048.1 - 0.0084 15.8 0.2 0.049 13.4 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_10 PF13460.1 KEY72048.1 - 0.024 14.6 0.3 0.054 13.5 0.2 1.6 1 0 0 1 1 1 0 NADH(P)-binding GIDA PF01134.17 KEY72048.1 - 0.036 12.9 0.1 0.055 12.3 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KEY72048.1 - 0.046 13.2 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 KEY72048.1 - 0.093 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Acyl-CoA_dh_1 PF00441.19 KEY72049.1 - 2.4e-26 92.6 0.3 4.2e-26 91.8 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 KEY72049.1 - 5.9e-21 74.0 0.0 1.4e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 KEY72049.1 - 2.5e-17 62.0 0.7 2.5e-17 62.0 0.5 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KEY72049.1 - 6.4e-07 29.9 0.2 2e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KEY72049.1 - 9.2e-06 25.9 0.0 1.7e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain zf-CCHC PF00098.18 KEY72050.1 - 1.9e-54 179.1 65.6 6.2e-09 35.3 1.7 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 KEY72050.1 - 2.3e-13 49.5 43.9 0.0019 17.8 0.2 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 KEY72050.1 - 1.5e-08 34.2 53.8 0.076 12.7 0.4 7.1 3 2 4 7 7 7 7 Zinc knuckle zf-CCHC_6 PF15288.1 KEY72050.1 - 3.3e-07 29.8 49.8 0.0074 15.9 0.7 6.9 4 2 3 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.1 KEY72050.1 - 0.0048 16.3 7.3 0.019 14.4 0.7 6.7 4 2 3 7 7 7 3 Zinc knuckle SAE2 PF08573.5 KEY72051.1 - 2.2e-21 76.3 2.8 2.6e-21 76.0 0.2 2.5 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus THOC7 PF05615.8 KEY72051.1 - 0.00015 22.0 0.6 0.00015 22.0 0.4 2.3 3 0 0 3 3 3 1 Tho complex subunit 7 UCH PF00443.24 KEY72052.1 - 4.9e-52 176.6 0.0 1.3e-51 175.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEY72052.1 - 4.9e-21 75.4 0.0 6.8e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCR_14kD PF02271.11 KEY72053.1 - 1.8e-40 136.8 0.7 2.1e-40 136.7 0.5 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.22 KEY72054.1 - 1.2e-69 230.0 1.2 8.1e-23 79.9 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein AhpC-TSA PF00578.16 KEY72055.1 - 1.3e-22 79.7 0.0 1.9e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KEY72055.1 - 2.1e-14 53.2 0.0 3.1e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 KEY72055.1 - 0.00079 19.3 0.0 0.0028 17.5 0.0 1.8 2 1 0 2 2 2 1 AhpC/TSA antioxidant enzyme HpaP PF09483.5 KEY72055.1 - 6.3 6.6 8.9 10 5.9 6.2 1.4 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Yae1_N PF09811.4 KEY72057.1 - 3e-09 36.2 6.0 4.8e-09 35.5 4.1 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Acetyltransf_1 PF00583.19 KEY72058.1 - 2.8e-14 52.9 0.0 5.1e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KEY72058.1 - 8.6e-07 28.6 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KEY72058.1 - 3.9e-05 23.7 0.0 0.0028 17.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KEY72058.1 - 0.011 15.9 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEY72058.1 - 0.015 15.1 0.1 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KEY72058.1 - 0.039 14.1 0.0 0.61 10.2 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF4646 PF15496.1 KEY72059.1 - 0.01 15.8 0.2 0.13 12.3 0.2 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4646) Sigma70_ner PF04546.8 KEY72059.1 - 0.93 9.0 8.1 47 3.5 0.0 2.8 2 1 0 2 2 2 0 Sigma-70, non-essential region CENP-Q PF13094.1 KEY72059.1 - 2.4 8.1 9.6 2.1 8.3 2.9 2.7 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit IF-2B PF01008.12 KEY72060.1 - 3.8e-46 157.3 0.1 1e-45 155.9 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family Ribosomal_S10 PF00338.17 KEY72060.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e NIF PF03031.13 KEY72061.1 - 5.9e-52 175.5 0.0 8.5e-52 175.0 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF4603 PF15376.1 KEY72061.1 - 0.19 8.8 6.5 0.26 8.4 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF1761 PF08570.5 KEY72062.1 - 1.8e-20 73.2 2.1 2e-20 73.0 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Ribosomal_L7Ae PF01248.21 KEY72063.1 - 1.9e-22 78.5 0.4 8e-22 76.5 0.2 2.0 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family UcrQ PF02939.11 KEY72064.1 - 2.8e-33 113.5 0.5 3.4e-33 113.2 0.3 1.1 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.20 KEY72065.1 - 1.7e-23 83.4 7.0 2.1e-23 83.1 4.5 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.3 KEY72065.1 - 0.049 12.5 5.3 0.064 12.1 3.7 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial RNase_T PF00929.19 KEY72066.1 - 1.7e-08 34.9 0.0 0.00045 20.5 0.0 2.3 2 0 0 2 2 2 2 Exonuclease zf-CCCH_2 PF14608.1 KEY72066.1 - 0.57 10.2 4.2 1.1 9.3 2.9 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type DUF676 PF05057.9 KEY72067.1 - 1.6e-50 171.4 0.0 2.3e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KEY72067.1 - 2.3e-05 24.4 0.0 0.00065 19.6 0.0 2.4 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY72067.1 - 7.9e-05 22.4 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KEY72067.1 - 0.00068 19.2 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 KEY72067.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PRELI PF04707.9 KEY72068.1 - 4e-20 71.9 0.1 4.4e-17 62.0 0.1 2.6 1 1 1 2 2 2 2 PRELI-like family bPH_2 PF03703.9 KEY72068.1 - 0.049 13.6 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial PH domain Pkinase PF00069.20 KEY72069.1 - 4.5e-09 35.8 0.0 1.4e-08 34.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY72069.1 - 4.6e-07 29.1 0.0 1.1e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase LMWPc PF01451.16 KEY72070.1 - 1.3e-38 132.3 0.0 1.5e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Pkinase PF00069.20 KEY72071.1 - 1.8e-67 227.2 0.0 2.4e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY72071.1 - 1.8e-27 96.0 0.0 5.2e-27 94.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEY72071.1 - 0.025 14.3 0.1 0.078 12.7 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KEY72071.1 - 0.12 11.4 0.0 0.59 9.1 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3455 PF11937.3 KEY72072.1 - 4.8e-25 88.5 0.0 6.4e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Hexapep PF00132.19 KEY72073.1 - 7e-11 41.1 6.9 4.5e-06 25.9 1.6 4.2 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KEY72073.1 - 9.7e-09 34.6 2.3 1.9e-07 30.5 1.0 2.6 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 KEY72073.1 - 0.088 11.3 0.1 0.12 10.9 0.1 1.2 1 0 0 1 1 1 0 L-fucokinase Apolipoprotein PF01442.13 KEY72074.1 - 0.0007 19.1 14.7 0.22 11.0 7.1 3.2 1 1 2 3 3 3 2 Apolipoprotein A1/A4/E domain CorA PF01544.13 KEY72074.1 - 0.016 14.2 0.7 0.13 11.3 0.0 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Globin PF00042.17 KEY72074.1 - 0.021 15.1 4.0 0.3 11.4 0.0 3.6 2 1 1 3 3 3 0 Globin Phasin_2 PF09361.5 KEY72074.1 - 0.15 12.0 19.2 0.74 9.8 0.1 5.2 5 1 0 5 5 5 0 Phasin protein DUF3562 PF12085.3 KEY72074.1 - 0.47 10.3 3.5 22 4.9 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3562) Syntaxin_2 PF14523.1 KEY72074.1 - 3.1 7.8 14.9 3.4 7.7 3.0 4.3 4 1 0 4 4 4 0 Syntaxin-like protein CHAD PF05235.9 KEY72074.1 - 4.1 6.9 7.1 14 5.2 0.1 2.9 2 1 1 3 3 3 0 CHAD domain Spore_III_AB PF09548.5 KEY72074.1 - 5.5 6.7 11.7 1.1 8.9 0.9 3.7 3 1 2 5 5 5 0 Stage III sporulation protein AB (spore_III_AB) MT0933_antitox PF14013.1 KEY72074.1 - 6.5 6.9 30.8 83 3.3 0.7 5.7 3 1 0 3 3 3 0 MT0933-like antitoxin protein CSTF2_hinge PF14327.1 KEY72074.1 - 10 6.3 6.9 7.2 6.7 0.1 3.6 4 1 1 5 5 5 0 Hinge domain of cleavage stimulation factor subunit 2 PRELI PF04707.9 KEY72075.1 - 1.1e-42 145.2 0.1 1.4e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family AATase PF07247.7 KEY72076.1 - 4.3e-12 45.3 0.0 4e-11 42.1 0.0 2.0 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KEY72076.1 - 1.3e-08 34.0 0.1 6.3e-08 31.8 0.1 1.9 1 1 0 1 1 1 1 Condensation domain AA_permease PF00324.16 KEY72077.1 - 1.2e-114 383.3 40.3 1.5e-114 383.0 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEY72077.1 - 3.1e-36 124.8 44.4 3.8e-36 124.5 30.8 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_M24 PF00557.19 KEY72078.1 - 1.2e-46 158.8 0.1 1.5e-46 158.5 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AAA_17 PF13207.1 KEY72079.1 - 1e-06 29.5 3.3 1.3e-05 25.9 2.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEY72079.1 - 3e-06 27.5 0.3 0.00072 19.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 KEY72079.1 - 4e-05 23.2 0.0 5.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 KEY72079.1 - 9.6e-05 21.5 0.6 0.0016 17.5 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 KEY72079.1 - 0.00095 19.0 1.8 0.023 14.5 1.3 2.4 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 KEY72079.1 - 0.0052 15.6 0.0 0.0073 15.1 0.0 1.2 1 0 0 1 1 1 1 ArgK protein NB-ARC PF00931.17 KEY72079.1 - 0.011 14.5 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 KEY72079.1 - 0.012 15.3 0.0 0.037 13.7 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 KEY72079.1 - 0.024 14.6 0.1 0.039 13.9 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Thymidylate_kin PF02223.12 KEY72079.1 - 0.026 13.9 0.0 0.86 8.9 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase NTPase_1 PF03266.10 KEY72079.1 - 0.028 14.1 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 NTPase T2SE PF00437.15 KEY72079.1 - 0.029 13.2 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.7 KEY72079.1 - 0.035 13.1 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 KEY72079.1 - 0.089 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 KEY72079.1 - 0.13 11.7 0.1 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AhpC-TSA_2 PF13911.1 KEY72080.1 - 3.2e-18 65.7 0.0 9.8e-18 64.1 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KEY72080.1 - 0.00015 21.3 0.0 0.00035 20.2 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KEY72080.1 - 0.00018 21.0 0.0 0.00037 20.0 0.0 1.5 1 0 0 1 1 1 1 Redoxin Gag_spuma PF03276.9 KEY72080.1 - 0.16 10.2 0.0 0.16 10.2 0.0 2.1 2 0 0 2 2 2 0 Spumavirus gag protein Peptidase_C26 PF07722.8 KEY72081.1 - 0.095 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase C26 F-box PF00646.28 KEY72083.1 - 0.00064 19.3 0.1 0.0017 17.9 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KEY72083.1 - 0.0057 16.3 0.1 0.0057 16.3 0.1 2.2 3 0 0 3 3 3 1 F-box-like Chitin_synth_1 PF01644.12 KEY72084.1 - 2.4e-80 268.0 0.5 4.1e-80 267.3 0.3 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KEY72084.1 - 6e-31 105.9 0.1 1.3e-30 104.9 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KEY72084.1 - 1e-24 86.8 0.0 3e-20 72.0 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 KEY72084.1 - 2.3e-07 30.8 0.0 7.8e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KEY72084.1 - 5.9e-07 29.3 13.2 5.9e-07 29.3 9.2 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 GbpC PF08363.5 KEY72084.1 - 0.18 11.0 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 Glucan-binding protein C Pro-kuma_activ PF09286.6 KEY72085.1 - 9.5e-24 84.0 0.0 2.5e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KEY72085.1 - 1.6e-09 37.3 0.0 2.4e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Translin PF01997.11 KEY72086.1 - 1.6e-46 158.4 0.0 1.8e-46 158.2 0.0 1.0 1 0 0 1 1 1 1 Translin family zf-CCCH PF00642.19 KEY72087.1 - 0.00022 20.8 2.8 0.00045 19.8 2.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEY72087.1 - 0.71 9.9 2.3 1.3 9.1 1.6 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Sec1 PF00995.18 KEY72088.1 - 3.3e-151 504.7 0.0 4.1e-151 504.4 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Ino80_Iec3 PF14612.1 KEY72089.1 - 2.5e-59 201.1 3.9 1.3e-35 123.5 0.4 2.3 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling Iso_dh PF00180.15 KEY72090.1 - 6e-71 239.2 0.0 7e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase adh_short PF00106.20 KEY72091.1 - 2.3e-27 95.9 0.2 2.3e-27 95.9 0.1 2.3 3 0 0 3 3 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY72091.1 - 5.2e-20 72.2 0.0 1.1e-19 71.1 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY72091.1 - 5.2e-12 45.8 0.4 5.2e-12 45.8 0.2 2.6 2 0 0 2 2 2 1 KR domain Myosin_tail_1 PF01576.14 KEY72091.1 - 0.00058 17.7 32.7 0.00058 17.7 22.7 3.5 3 1 1 4 4 4 1 Myosin tail Epimerase PF01370.16 KEY72091.1 - 0.0026 17.2 0.1 0.0077 15.6 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Filament PF00038.16 KEY72091.1 - 0.0082 15.6 18.1 0.0082 15.6 12.5 4.9 3 1 1 5 5 5 1 Intermediate filament protein DUF1776 PF08643.5 KEY72091.1 - 0.01 15.0 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TSC22 PF01166.13 KEY72091.1 - 0.026 14.4 21.3 0.097 12.6 0.2 4.9 5 0 0 5 5 4 0 TSC-22/dip/bun family 3HCDH_N PF02737.13 KEY72091.1 - 0.062 12.9 0.0 0.062 12.9 0.0 4.6 4 1 1 5 5 5 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Reo_sigmaC PF04582.7 KEY72091.1 - 0.21 10.7 14.1 0.21 10.7 2.9 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 KEY72091.1 - 0.22 11.0 59.8 0.076 12.5 15.6 4.4 2 1 2 4 4 4 0 IncA protein DUF1664 PF07889.7 KEY72091.1 - 0.6 9.9 20.6 0.21 11.4 4.5 4.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) EzrA PF06160.7 KEY72091.1 - 3.2 5.8 34.4 1.2 7.1 13.1 2.7 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA TMF_DNA_bd PF12329.3 KEY72091.1 - 3.5 7.5 76.1 0.16 11.7 1.3 7.9 5 1 3 8 8 8 0 TATA element modulatory factor 1 DNA binding WEMBL PF05701.6 KEY72091.1 - 5.8 5.2 66.0 0.72 8.2 37.6 3.1 2 1 0 2 2 2 0 Weak chloroplast movement under blue light Fib_alpha PF08702.5 KEY72091.1 - 6.6 6.8 30.9 0.058 13.5 7.4 4.2 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family NYD-SP28_assoc PF14775.1 KEY72091.1 - 9.5 6.0 17.8 5.4 6.7 0.5 3.7 3 0 0 3 3 3 0 Sperm tail C-terminal domain Salp15 PF12115.3 KEY72093.1 - 0.16 12.2 7.3 0.35 11.1 4.9 1.8 1 1 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation zf-C2H2_4 PF13894.1 KEY72093.1 - 0.18 12.2 28.9 0.56 10.6 0.4 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C3HC4 PF00097.20 KEY72093.1 - 7.7 6.2 10.7 0.6 9.8 2.8 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Not3 PF04065.10 KEY72094.1 - 1.3e-98 328.9 26.6 2.1e-98 328.2 18.5 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 KEY72094.1 - 1.3e-43 148.0 7.6 4.7e-43 146.2 5.2 2.0 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 KEY72094.1 - 0.0054 16.2 3.6 0.012 15.1 2.5 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.8 KEY72094.1 - 0.012 15.5 1.7 0.012 15.5 1.2 2.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF1192 PF06698.6 KEY72094.1 - 0.019 14.7 1.6 0.019 14.7 1.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Sec5 PF15469.1 KEY72094.1 - 0.21 11.3 12.3 0.25 11.0 2.4 2.4 2 0 0 2 2 2 0 Exocyst complex component Sec5 Poty_PP PF08440.5 KEY72094.1 - 0.87 8.5 8.0 0.43 9.5 2.9 2.1 1 1 1 2 2 2 0 Potyviridae polyprotein NPV_P10 PF05531.7 KEY72094.1 - 0.9 9.8 4.4 1.7 8.9 0.1 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF904 PF06005.7 KEY72094.1 - 2 8.7 19.1 0.09 13.0 0.6 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Prefoldin PF02996.12 KEY72094.1 - 2.9 7.5 14.3 0.097 12.3 1.8 3.2 2 1 0 2 2 2 0 Prefoldin subunit Lzipper-MIP1 PF14389.1 KEY72094.1 - 3.6 7.7 12.0 0.73 9.9 1.3 2.9 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Snapin_Pallidin PF14712.1 KEY72094.1 - 7.7 6.8 13.9 0.6 10.4 0.2 2.8 2 1 1 3 3 3 0 Snapin/Pallidin Tyr_Deacylase PF02580.11 KEY72095.1 - 5.9e-37 126.8 0.4 2.6e-20 72.9 0.0 2.1 2 0 0 2 2 2 2 D-Tyr-tRNA(Tyr) deacylase Pro_isomerase PF00160.16 KEY72096.1 - 3.6e-47 160.4 0.2 5.7e-47 159.7 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 KEY72096.1 - 1e-07 31.4 9.1 0.00014 21.4 0.2 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KEY72096.1 - 2.8e-05 23.6 6.8 0.00026 20.6 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEY72096.1 - 0.0011 18.6 0.2 0.0047 16.6 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEY72096.1 - 0.011 15.6 1.1 0.026 14.4 0.7 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.1 KEY72096.1 - 0.016 15.0 2.6 0.029 14.2 1.8 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEY72096.1 - 0.022 14.3 0.2 0.022 14.3 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEY72096.1 - 0.11 13.1 6.4 0.2 12.3 1.2 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEY72096.1 - 0.16 12.6 9.8 0.11 13.2 4.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat RasGAP PF00616.14 KEY72097.1 - 1.1e-39 136.1 0.0 2.9e-39 134.7 0.0 1.7 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 KEY72097.1 - 0.0008 19.2 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain MRP-L20 PF12824.2 KEY72099.1 - 7e-49 165.9 5.3 8.1e-49 165.7 3.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 KEY72099.1 - 4.3e-05 23.4 0.2 0.00016 21.5 0.1 1.9 2 0 0 2 2 2 1 Neugrin CBM_20 PF00686.14 KEY72100.1 - 1.4e-32 111.1 1.6 2.7e-32 110.2 1.1 1.5 1 0 0 1 1 1 1 Starch binding domain Chitin_bind_3 PF03067.10 KEY72100.1 - 5.8e-09 36.4 2.5 1.2e-05 25.6 0.0 2.8 3 1 0 3 3 3 2 Chitin binding domain Cu-oxidase_4 PF02578.10 KEY72103.1 - 2e-27 95.7 0.0 4.7e-27 94.5 0.0 1.5 1 1 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase Cu_amine_oxid PF01179.15 KEY72103.1 - 0.21 10.2 0.0 0.28 9.8 0.0 1.1 1 0 0 1 1 1 0 Copper amine oxidase, enzyme domain Pectinesterase PF01095.14 KEY72105.1 - 1.8e-45 154.7 3.2 2.4e-45 154.3 2.3 1.1 1 0 0 1 1 1 1 Pectinesterase Zn_clus PF00172.13 KEY72106.1 - 2e-09 37.1 8.5 3.7e-09 36.3 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEY72106.1 - 0.00024 19.8 0.1 0.00032 19.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 KEY72107.1 - 6.9e-41 140.1 6.8 9.2e-41 139.7 4.7 1.1 1 0 0 1 1 1 1 RTA1 like protein UNC-50 PF05216.8 KEY72107.1 - 0.0025 17.0 1.4 0.021 14.0 0.0 2.4 2 0 0 2 2 2 1 UNC-50 family PalH PF08733.5 KEY72107.1 - 1.4 7.7 10.3 0.41 9.4 4.5 1.9 2 0 0 2 2 2 0 PalH/RIM21 LHC PF00556.15 KEY72107.1 - 3.4 7.6 6.2 3.7 7.4 0.6 2.6 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit Ank_2 PF12796.2 KEY72110.1 - 2.8e-18 66.0 0.0 1.1e-10 41.6 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEY72110.1 - 4.6e-15 55.2 0.5 3.2e-06 27.1 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 KEY72110.1 - 1.3e-13 49.9 0.0 0.0043 16.7 0.0 4.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KEY72110.1 - 5.4e-08 32.3 0.0 0.26 11.6 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KEY72110.1 - 9.2e-07 29.2 0.2 0.013 15.9 0.0 3.7 2 1 3 5 5 5 3 Ankyrin repeats (many copies) vWA-TerF-like PF10138.4 KEY72110.1 - 0.00041 20.2 0.0 0.00075 19.3 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 KEY72110.1 - 0.0017 18.0 0.0 0.017 14.8 0.0 2.4 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KEY72110.1 - 0.013 15.6 0.0 0.11 12.6 0.0 2.5 2 1 0 2 2 2 0 von Willebrand factor type A domain Zn_clus PF00172.13 KEY72111.1 - 0.0068 16.2 16.4 0.0068 16.2 11.4 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PepSY_TM_1 PF13172.1 KEY72111.1 - 0.026 14.2 0.2 0.053 13.2 0.1 1.6 1 0 0 1 1 1 0 PepSY-associated TM helix Oxidored_q6 PF01058.17 KEY72112.1 - 5.1e-22 77.8 0.1 7.8e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit MARVEL PF01284.18 KEY72113.1 - 0.075 12.8 7.9 0.12 12.2 5.5 1.4 1 1 0 1 1 1 0 Membrane-associating domain DUF4064 PF13273.1 KEY72113.1 - 0.091 12.8 0.4 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4231 PF14015.1 KEY72113.1 - 5.3 7.0 7.4 1.5e+02 2.3 5.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Reticulon PF02453.12 KEY72114.1 - 1.9e-20 73.1 0.0 3.9e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Reticulon ATP-synt_B PF00430.13 KEY72114.1 - 5.8 6.7 17.3 0.43 10.3 5.9 2.3 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Peptidase_M64 PF09471.5 KEY72116.1 - 1.1e-20 74.3 0.0 4.9e-19 68.9 0.0 2.2 1 1 0 1 1 1 1 IgA Peptidase M64 HAD_2 PF13419.1 KEY72118.1 - 9.9e-19 68.2 0.1 2.2e-18 67.0 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Sulfotransfer_3 PF13469.1 KEY72118.1 - 9.8e-05 23.3 0.1 0.00051 21.0 0.0 2.2 2 1 0 2 2 2 1 Sulfotransferase family Hydrolase_like PF13242.1 KEY72118.1 - 0.0011 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Sulfotransfer_1 PF00685.22 KEY72118.1 - 0.0044 16.3 0.0 0.9 8.7 0.0 2.7 1 1 0 1 1 1 1 Sulfotransferase domain Hydrolase PF00702.21 KEY72118.1 - 0.0049 17.3 0.1 0.014 15.8 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEY72118.1 - 0.14 11.6 0.0 0.79 9.2 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF1996 PF09362.5 KEY72119.1 - 8e-82 274.4 1.4 8e-82 274.4 1.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) Pkinase PF00069.20 KEY72120.1 - 3.6e-34 118.1 0.0 6.2e-34 117.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY72120.1 - 3.7e-11 42.5 0.1 0.00027 20.1 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KEY72120.1 - 0.00049 19.0 0.5 0.00074 18.4 0.4 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Sin_N PF04801.8 KEY72120.1 - 0.081 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region FPN1 PF06963.7 KEY72121.1 - 9.4e-110 366.9 22.2 1.8e-109 366.0 15.4 1.4 1 1 0 1 1 1 1 Ferroportin1 (FPN1) BATS PF06968.8 KEY72123.1 - 7e-30 102.7 0.0 2.2e-29 101.1 0.0 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 KEY72123.1 - 3.9e-17 62.9 0.1 6.9e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily MFS_1 PF07690.11 KEY72125.1 - 5.6e-35 120.6 33.1 8.1e-35 120.1 22.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY72125.1 - 0.00042 19.0 20.4 0.0011 17.6 14.1 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter UNC-93 PF05978.11 KEY72125.1 - 0.0075 15.7 3.1 0.0075 15.7 2.2 2.2 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 zf-C2H2 PF00096.21 KEY72126.1 - 4.8e-06 26.5 14.0 0.11 12.8 1.6 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY72126.1 - 1.2e-05 25.2 13.7 0.068 13.5 1.2 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEY72126.1 - 0.021 15.0 16.4 2 8.8 0.4 4.4 4 0 0 4 4 4 0 Zinc-finger double domain Leu_zip PF15294.1 KEY72126.1 - 0.021 13.9 0.8 0.032 13.3 0.5 1.2 1 0 0 1 1 1 0 Leucine zipper DivIC PF04977.10 KEY72126.1 - 0.2 11.1 1.7 0.38 10.2 0.9 1.7 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 KEY72126.1 - 1.3 8.6 4.2 2.1 7.9 2.9 1.2 1 0 0 1 1 1 0 IncA protein FCH PF00611.18 KEY72127.1 - 2e-24 85.5 0.1 2e-24 85.5 0.1 2.9 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 KEY72127.1 - 7.2e-18 63.9 0.5 2.9e-10 39.5 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.17 KEY72127.1 - 3e-14 52.4 5.3 4.8e-14 51.8 3.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.23 KEY72127.1 - 1.9e-13 49.5 0.0 1.7e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_3 PF08239.6 KEY72127.1 - 4.1e-05 23.6 1.3 0.005 16.9 0.2 2.6 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_2 PF07653.12 KEY72127.1 - 0.00014 21.2 0.0 0.096 12.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain Allexi_40kDa PF05549.6 KEY72127.1 - 0.057 12.7 1.5 0.25 10.6 0.0 2.4 2 1 0 2 2 2 0 Allexivirus 40kDa protein DUF3450 PF11932.3 KEY72127.1 - 0.28 10.4 5.9 0.086 12.0 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) C1_2 PF03107.11 KEY72127.1 - 0.56 10.3 7.8 0.99 9.5 5.4 1.4 1 0 0 1 1 1 0 C1 domain DUF2894 PF11445.3 KEY72127.1 - 9.7 6.3 13.8 0.12 12.6 2.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2894) AMP-binding PF00501.23 KEY72128.1 - 3.8e-89 298.9 0.0 4.4e-89 298.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEY72128.1 - 3.5e-14 53.5 0.1 1.2e-13 51.8 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 KEY72128.1 - 0.0014 17.2 0.0 0.0085 14.6 0.0 1.9 2 0 0 2 2 2 1 GH3 auxin-responsive promoter SLAC1 PF03595.12 KEY72131.1 - 2.4e-81 272.9 43.9 2.8e-81 272.7 30.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel YCII PF03795.9 KEY72132.1 - 1.2e-09 38.1 0.0 1.4e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain PS_Dcarbxylase PF02666.10 KEY72132.1 - 0.096 11.9 0.0 0.096 11.9 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase DUF2408 PF10303.4 KEY72133.1 - 2.2e-45 154.0 9.0 9.2e-28 97.0 0.2 4.9 3 1 2 5 5 5 3 Protein of unknown function (DUF2408) V_ATPase_I PF01496.14 KEY72133.1 - 0.062 11.1 0.7 0.094 10.5 0.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1539 PF07560.6 KEY72133.1 - 0.82 9.5 3.9 1 9.2 0.3 2.4 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) DUF342 PF03961.8 KEY72133.1 - 6.9 4.9 8.7 0.22 9.9 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF342) ING PF12998.2 KEY72133.1 - 9.6 6.5 11.5 6.9 6.9 2.5 3.6 3 1 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Ribosomal_60s PF00428.14 KEY72134.1 - 2e-25 88.9 11.0 2.4e-25 88.7 7.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Gly-zipper_OmpA PF13436.1 KEY72134.1 - 0.14 11.7 6.1 0.2 11.3 4.2 1.1 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain UBX PF00789.15 KEY72135.1 - 1.2e-06 28.5 0.2 3.3e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 UBX domain UBA PF00627.26 KEY72135.1 - 0.00039 20.1 0.0 0.0012 18.6 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Ima1_N PF09779.4 KEY72135.1 - 0.0029 18.1 2.3 0.0029 18.1 1.6 2.3 1 1 1 2 2 2 1 Ima1 N-terminal domain SOBP PF15279.1 KEY72135.1 - 0.22 11.8 10.9 0.26 11.6 7.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Vps39_2 PF10367.4 KEY72135.1 - 1.7 8.8 0.0 1.7 8.8 0.0 2.7 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Motile_Sperm PF00635.21 KEY72136.1 - 8.9e-25 86.4 0.5 2.1e-24 85.2 0.2 1.8 1 1 1 2 2 2 1 MSP (Major sperm protein) domain DUF756 PF05506.7 KEY72136.1 - 0.066 13.7 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF756) FA_desaturase PF00487.19 KEY72137.1 - 1.3e-31 110.0 16.9 1.3e-31 110.0 11.7 4.9 2 2 3 5 5 5 2 Fatty acid desaturase Aa_trans PF01490.13 KEY72137.1 - 4.1e-26 91.4 32.5 6.5e-26 90.7 22.6 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Lipid_DES PF08557.5 KEY72137.1 - 1.5e-20 72.0 0.2 3.6e-20 70.9 0.1 1.7 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) ICE2 PF08426.5 KEY72138.1 - 1.7e-132 441.9 16.2 2e-132 441.7 11.2 1.0 1 0 0 1 1 1 1 ICE2 Abhydrolase_5 PF12695.2 KEY72139.1 - 9e-10 38.4 0.2 1.3e-09 37.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEY72139.1 - 0.00014 21.1 0.0 0.21 10.7 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family PhoPQ_related PF10142.4 KEY72139.1 - 0.025 13.0 0.0 0.034 12.6 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein DUF218 PF02698.12 KEY72140.1 - 2.9e-10 39.8 0.0 4.4e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Mur_ligase_M PF08245.7 KEY72141.1 - 6.6e-07 29.5 0.0 1.6e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain Pkinase PF00069.20 KEY72143.1 - 1e-68 231.3 0.0 1.5e-68 230.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY72143.1 - 1.5e-49 168.4 0.0 2.4e-49 167.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY72143.1 - 0.0031 16.5 0.0 0.01 14.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KEY72143.1 - 0.11 11.4 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RTTN_N PF14726.1 KEY72143.1 - 0.24 11.9 1.5 3.5 8.2 0.3 2.5 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning Wzz PF02706.10 KEY72144.1 - 3.2 7.5 8.9 6.3 6.6 6.2 1.4 1 0 0 1 1 1 0 Chain length determinant protein Ank PF00023.25 KEY72147.1 - 2.7e-15 55.3 0.8 3.5e-07 29.6 0.2 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 KEY72147.1 - 1.7e-14 53.9 0.4 3.7e-05 23.9 0.0 3.3 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEY72147.1 - 3.9e-12 46.3 2.5 0.00047 20.5 0.2 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY72147.1 - 2.7e-10 40.1 1.4 1.9e-05 24.7 0.1 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY72147.1 - 4.3e-09 35.7 0.3 0.15 12.4 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 KEY72147.1 - 2.8e-06 26.8 0.5 5.6e-05 22.7 0.3 2.8 2 1 0 2 2 2 1 KilA-N domain Actin PF00022.14 KEY72148.1 - 1.1e-130 435.6 0.0 1.2e-130 435.4 0.0 1.0 1 0 0 1 1 1 1 Actin DUF3602 PF12223.3 KEY72149.1 - 8.2e-11 42.1 8.5 4.6e-06 26.9 1.0 2.6 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) zf-MYND PF01753.13 KEY72150.1 - 0.0002 21.1 14.7 0.007 16.2 4.3 2.3 2 0 0 2 2 2 2 MYND finger Glyco_hydro_76 PF03663.9 KEY72151.1 - 9.8e-147 489.1 8.5 1.3e-146 488.7 5.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KEY72151.1 - 0.0069 15.4 8.7 0.22 10.5 0.1 3.1 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 COPIIcoated_ERV PF07970.7 KEY72152.1 - 6.1e-36 124.1 0.1 8.7e-36 123.6 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KEY72152.1 - 1.9e-23 82.2 0.0 3e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF533 PF04391.7 KEY72153.1 - 0.036 13.4 20.1 0.026 13.9 1.4 4.2 2 1 3 5 5 5 0 Protein of unknown function (DUF533) Gly-zipper_OmpA PF13436.1 KEY72153.1 - 0.039 13.6 0.2 0.039 13.6 0.1 4.1 2 1 3 5 5 5 0 Glycine-zipper containing OmpA-like membrane domain DUF4366 PF14283.1 KEY72153.1 - 1.9 7.8 4.0 11 5.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) DUF2910 PF11139.3 KEY72153.1 - 3.6 6.6 10.9 0.91 8.6 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2910) DnaJ PF00226.26 KEY72154.1 - 2.7e-27 94.2 2.0 4.2e-27 93.6 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KEY72154.1 - 2.1e-15 56.5 17.4 3.4e-15 55.8 12.0 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 KEY72154.1 - 4.1e-11 42.6 0.0 1.1e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 DnaJ C terminal domain HypA PF01155.14 KEY72154.1 - 0.00063 19.4 8.3 0.023 14.3 0.9 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family DUF3961 PF13106.1 KEY72154.1 - 0.15 11.6 0.3 0.28 10.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) zf-TFIIB PF13453.1 KEY72154.1 - 4.8 6.4 14.9 14 4.9 0.8 4.3 4 0 0 4 4 4 0 Transcription factor zinc-finger OB_NTP_bind PF07717.11 KEY72155.1 - 4.8e-28 97.2 0.0 1e-27 96.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KEY72155.1 - 1.4e-22 79.6 2.7 1.6e-22 79.3 0.0 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KEY72155.1 - 1e-12 47.7 0.0 2.5e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KEY72155.1 - 2.1e-05 24.6 0.0 7.2e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KEY72155.1 - 6.1e-05 22.5 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KEY72155.1 - 0.00059 18.8 0.0 0.0013 17.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 KEY72155.1 - 0.019 14.8 0.1 0.29 11.0 0.1 2.7 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 KEY72155.1 - 0.026 13.9 0.1 0.056 12.8 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 KEY72155.1 - 0.046 14.0 0.4 0.25 11.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter GYD PF08734.6 KEY72155.1 - 0.13 12.0 0.5 19 5.0 0.0 3.2 3 0 0 3 3 3 0 GYD domain cobW PF02492.14 KEY72155.1 - 0.14 11.5 0.2 0.82 9.0 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain His_Phos_1 PF00300.17 KEY72156.1 - 6.9e-20 71.7 0.0 8.5e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Chromate_transp PF02417.10 KEY72157.1 - 3.3e-46 156.9 36.8 9e-27 93.7 11.3 2.7 3 0 0 3 3 3 2 Chromate transporter Herpes_UL3 PF03369.8 KEY72157.1 - 0.026 14.5 0.1 0.041 13.8 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL3 protein HET PF06985.6 KEY72158.1 - 1.6e-28 99.6 0.0 2.9e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 KEY72159.1 - 7.9e-49 163.9 3.0 6.4e-10 39.2 0.0 9.4 7 4 3 10 10 10 7 Ankyrin repeats (3 copies) Ank PF00023.25 KEY72159.1 - 1.7e-40 134.8 28.7 0.0012 18.5 0.0 14.2 14 0 0 14 14 14 9 Ankyrin repeat Ank_3 PF13606.1 KEY72159.1 - 2.3e-31 104.6 16.8 0.012 15.8 0.0 13.1 13 0 0 13 13 13 8 Ankyrin repeat Ank_4 PF13637.1 KEY72159.1 - 7.7e-28 96.3 9.8 0.0024 18.3 0.1 10.7 7 4 4 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY72159.1 - 1.9e-20 72.3 22.9 0.027 14.7 0.1 10.5 9 4 3 12 12 12 7 Ankyrin repeats (many copies) F-box-like PF12937.2 KEY72159.1 - 0.0013 18.4 0.1 0.0034 17.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like Ribosomal_S17e PF00833.13 KEY72160.1 - 2.8e-54 182.0 0.1 3.4e-54 181.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 KEY72160.1 - 0.052 14.2 0.1 0.067 13.8 0.0 1.3 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal Sugar_tr PF00083.19 KEY72161.1 - 8.4e-86 288.3 14.0 1.4e-85 287.5 9.7 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY72161.1 - 1.2e-30 106.5 27.5 4e-30 104.7 15.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Asp_Glu_race PF01177.17 KEY72162.1 - 5.7e-20 72.1 0.0 6.6e-20 71.9 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase TetR_C_9 PF14514.1 KEY72162.1 - 0.15 11.8 0.0 0.43 10.4 0.0 1.8 2 1 0 2 2 2 0 Transcriptional regulator, TetR, C-terminal Actin PF00022.14 KEY72163.1 - 1.5e-110 369.3 0.0 1.8e-110 369.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KEY72163.1 - 0.053 12.1 0.0 1.2 7.6 0.0 2.6 2 1 0 2 2 2 0 MreB/Mbl protein Pkinase PF00069.20 KEY72164.1 - 4.1e-60 203.1 0.0 5.3e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY72164.1 - 5.6e-31 107.5 0.0 7.9e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY72164.1 - 0.0058 15.6 0.0 0.0098 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Arf PF00025.16 KEY72165.1 - 1.5e-75 252.2 0.1 1.8e-75 252.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KEY72165.1 - 9.1e-13 47.8 0.0 1.1e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KEY72165.1 - 1.8e-12 46.9 0.0 2.1e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KEY72165.1 - 6.1e-12 44.9 1.9 1.3e-08 33.9 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KEY72165.1 - 4.4e-11 42.3 0.0 5.4e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KEY72165.1 - 1.3e-07 32.1 0.0 1.9e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KEY72165.1 - 0.00016 21.5 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KEY72165.1 - 0.025 13.6 0.3 0.098 11.7 0.1 1.8 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF1325 PF07039.6 KEY72166.1 - 1.7e-27 95.5 0.0 2.8e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain Mucin PF01456.12 KEY72166.1 - 0.023 14.4 14.7 0.041 13.6 10.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 KEY72166.1 - 0.028 12.4 8.8 0.038 11.9 6.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 KEY72166.1 - 0.57 9.9 9.1 1.2 8.9 6.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF1777 PF08648.7 KEY72166.1 - 9.4 5.9 23.0 1.1 9.0 1.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1777) PMI_typeI PF01238.16 KEY72167.1 - 4.5e-133 443.8 0.0 5.3e-133 443.5 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Zn_clus PF00172.13 KEY72168.1 - 1.5e-08 34.3 7.6 2.3e-08 33.8 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.16 KEY72170.1 - 2.8e-34 118.5 0.0 4.6e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 KEY72170.1 - 2.8e-15 55.6 0.0 5.9e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY72170.1 - 2.2e-10 40.3 0.0 4.4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY72170.1 - 1.4e-08 34.4 0.0 3.2e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3659 PF12396.3 KEY72170.1 - 0.055 13.1 0.2 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) Activator_LAG-3 PF11498.3 KEY72171.1 - 0.0011 17.8 0.2 0.0011 17.8 0.2 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 HARP PF07443.8 KEY72171.1 - 0.047 13.0 0.2 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 HepA-related protein (HARP) ARGLU PF15346.1 KEY72171.1 - 0.063 13.0 0.9 0.11 12.2 0.6 1.4 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Dmrt1 PF12374.3 KEY72171.1 - 0.15 12.4 2.7 0.22 11.8 1.9 1.3 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 FliT PF05400.8 KEY72171.1 - 0.18 12.2 1.2 0.31 11.4 0.1 1.9 2 0 0 2 2 2 0 Flagellar protein FliT Methyltransf_16 PF10294.4 KEY72172.1 - 1.1e-17 64.0 0.0 1.7e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KEY72172.1 - 4.9e-07 30.3 0.0 8.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KEY72172.1 - 2.6e-05 23.9 0.0 4.3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 KEY72172.1 - 3.1e-05 23.4 0.0 5.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KEY72172.1 - 0.0044 16.5 0.0 0.0074 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 KEY72172.1 - 0.0057 15.8 0.0 0.0083 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 KEY72172.1 - 0.023 14.3 0.1 0.037 13.6 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KEY72172.1 - 0.046 14.2 0.0 0.088 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KEY72172.1 - 0.055 13.1 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S24e PF01282.14 KEY72173.1 - 7.7e-34 115.3 0.0 1.3e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Thrombin_light PF09396.5 KEY72174.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Thrombin light chain GTP_cyclohydro2 PF00925.15 KEY72176.1 - 2.4e-59 199.3 0.1 2.4e-57 192.8 0.0 2.1 1 1 0 1 1 1 1 GTP cyclohydrolase II Cerato-platanin PF07249.7 KEY72177.1 - 0.0016 18.4 0.6 0.0032 17.4 0.1 1.7 2 0 0 2 2 2 1 Cerato-platanin FHA PF00498.21 KEY72179.1 - 8.2e-06 25.8 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 FHA domain NDUF_B7 PF05676.8 KEY72180.1 - 5.6e-32 108.9 4.7 6.5e-32 108.7 3.3 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 KEY72180.1 - 0.00025 20.7 3.6 0.00038 20.1 2.5 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like PTH2 PF01981.11 KEY72181.1 - 0.077 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 Galactosyl_T PF01762.16 KEY72183.1 - 1.8e-13 50.5 1.3 3.6e-12 46.3 0.9 2.1 1 1 0 1 1 1 1 Galactosyltransferase DUF1304 PF06993.7 KEY72184.1 - 1.1e-41 141.0 4.0 1.2e-41 140.9 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) Recep_L_domain PF01030.19 KEY72185.1 - 2.5e-10 40.3 0.0 0.0064 16.4 0.0 4.0 3 2 0 3 3 3 3 Receptor L domain SKG6 PF08693.5 KEY72185.1 - 0.0019 17.4 0.5 0.0039 16.4 0.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain G_glu_transpept PF01019.16 KEY72186.1 - 2.2e-145 485.0 0.0 2.5e-145 484.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase NMT1_2 PF13379.1 KEY72186.1 - 0.028 13.8 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family Glutaredoxin PF00462.19 KEY72187.1 - 7.5e-16 57.8 0.0 1.3e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Synthase_beta PF11421.3 KEY72187.1 - 0.14 12.8 2.0 0.17 12.5 0.2 1.9 2 0 0 2 2 2 0 ATP synthase F1 beta subunit DUF972 PF06156.8 KEY72188.1 - 0.23 11.8 4.3 4.6 7.6 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DivIC PF04977.10 KEY72188.1 - 0.37 10.3 8.0 6.5 6.3 4.5 2.7 2 0 0 2 2 2 0 Septum formation initiator APG6 PF04111.7 KEY72188.1 - 0.56 9.1 12.3 1.4 7.8 1.8 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 ERM PF00769.14 KEY72188.1 - 0.73 9.3 11.4 0.44 10.0 4.0 2.5 2 1 0 2 2 2 0 Ezrin/radixin/moesin family HR1 PF02185.11 KEY72189.1 - 0.28 10.9 20.4 0.33 10.7 3.8 3.6 3 1 0 3 3 3 0 Hr1 repeat SOBP PF15279.1 KEY72189.1 - 2 8.7 12.7 2.8 8.2 8.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Reo_sigmaC PF04582.7 KEY72190.1 - 0.027 13.6 0.3 0.045 12.9 0.2 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF2145 PF09916.4 KEY72190.1 - 0.09 12.2 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) GerE PF00196.14 KEY72190.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Aminotran_4 PF01063.14 KEY72191.1 - 5e-23 81.7 0.0 7e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV CTP_transf_2 PF01467.21 KEY72192.1 - 0.011 15.7 0.0 5.2 7.0 0.0 2.7 2 0 0 2 2 2 0 Cytidylyltransferase His_Phos_1 PF00300.17 KEY72194.1 - 6.7e-15 55.5 0.0 9.8e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RF-1 PF00472.15 KEY72196.1 - 1.9e-33 114.6 4.4 4e-33 113.6 3.0 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 KEY72196.1 - 2.1e-20 72.5 0.0 5.8e-20 71.1 0.0 1.8 2 0 0 2 2 2 1 PCRF domain COX16 PF14138.1 KEY72196.1 - 0.27 11.4 2.0 9.1 6.5 0.0 2.7 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein COX16 Pec_lyase_C PF00544.14 KEY72197.1 - 1.8e-18 66.7 0.4 2.7e-18 66.1 0.3 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KEY72197.1 - 0.0018 18.0 5.3 0.0034 17.1 3.7 1.4 1 0 0 1 1 1 1 Right handed beta helix region zf-C2H2_4 PF13894.1 KEY72198.1 - 1.7e-10 40.4 26.2 0.033 14.4 2.9 5.8 5 0 0 5 5 5 4 C2H2-type zinc finger NACHT PF05729.7 KEY72198.1 - 1.4e-09 37.8 0.0 4.2e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain zf-C2H2 PF00096.21 KEY72198.1 - 5.7e-06 26.3 30.2 0.0005 20.2 4.2 5.7 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KEY72198.1 - 6.6e-05 23.0 0.4 6.6e-05 23.0 0.2 5.3 5 1 0 5 5 5 1 Zinc-finger double domain AAA_16 PF13191.1 KEY72198.1 - 0.001 19.0 0.2 0.035 14.0 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain Abhydrolase_6 PF12697.2 KEY72198.1 - 0.0079 16.0 0.0 0.03 14.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KEY72198.1 - 0.014 14.7 0.0 0.032 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative serine esterase (DUF676) zf-met PF12874.2 KEY72198.1 - 0.017 15.3 12.5 0.033 14.3 1.7 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KEY72198.1 - 0.069 13.3 13.0 0.09 12.9 2.3 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KEY72198.1 - 0.44 10.3 6.5 0.19 11.5 2.4 2.0 2 0 0 2 2 2 0 BED zinc finger SNF2_N PF00176.18 KEY72199.1 - 4.9e-52 176.5 0.0 6.8e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEY72199.1 - 1.4e-07 31.3 0.0 2.8e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEY72199.1 - 5.1e-06 26.4 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit APH PF01636.18 KEY72200.1 - 8.4e-06 25.6 0.1 1.8e-05 24.5 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KEY72200.1 - 0.0013 17.9 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KEY72200.1 - 0.0013 17.8 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KEY72200.1 - 0.0035 16.7 0.0 0.0084 15.4 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 KEY72200.1 - 0.032 13.8 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase SlyX PF04102.7 KEY72202.1 - 0.044 14.1 0.4 0.1 12.9 0.2 1.6 1 0 0 1 1 1 0 SlyX HOOK PF05622.7 KEY72205.1 - 0.0052 14.6 22.4 0.0064 14.3 15.6 1.3 1 0 0 1 1 1 1 HOOK protein BLOC1_2 PF10046.4 KEY72205.1 - 0.011 15.8 7.1 6.7 6.9 0.2 3.6 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.2 KEY72205.1 - 0.073 12.9 27.7 0.18 11.6 8.1 3.8 1 1 1 2 2 2 0 Tropomyosin like Laminin_II PF06009.7 KEY72205.1 - 0.2 11.3 15.1 0.6 9.8 1.1 3.6 1 1 3 4 4 4 0 Laminin Domain II AAA_13 PF13166.1 KEY72205.1 - 0.45 8.9 12.7 0.14 10.6 6.3 1.7 1 1 1 2 2 2 0 AAA domain DUF1664 PF07889.7 KEY72205.1 - 1 9.1 17.8 0.93 9.3 1.1 4.4 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 KEY72205.1 - 2.4 7.9 10.6 0.96 9.2 2.1 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus PspB PF06667.7 KEY72205.1 - 3.1 7.7 8.7 3.2 7.7 0.1 3.9 2 2 2 4 4 4 0 Phage shock protein B IncA PF04156.9 KEY72205.1 - 3.2 7.3 26.4 6e+02 -0.2 18.3 3.1 1 1 0 1 1 1 0 IncA protein CENP-F_leu_zip PF10473.4 KEY72205.1 - 4.1 7.2 29.4 0.089 12.6 8.8 3.6 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KEY72205.1 - 5.9 5.9 9.1 10 5.1 0.4 2.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein TMP_2 PF06791.8 KEY72205.1 - 7.5 6.1 7.3 9.6 5.7 0.3 3.0 2 1 1 3 3 3 0 Prophage tail length tape measure protein DUF3357 PF11837.3 KEY72206.1 - 0.00074 19.3 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) RskA PF10099.4 KEY72206.1 - 0.054 13.2 0.1 0.083 12.6 0.1 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DPBB_1 PF03330.13 KEY72206.1 - 0.071 13.1 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF3040 PF11239.3 KEY72206.1 - 0.092 12.8 0.4 0.2 11.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Pkinase PF00069.20 KEY72207.1 - 1.5e-21 76.7 0.0 4.4e-21 75.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY72207.1 - 2.4e-15 56.3 0.0 3.5e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4246 PF14033.1 KEY72208.1 - 3.8e-161 537.1 0.0 4.2e-160 533.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 KEY72208.1 - 0.018 15.3 0.0 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DUF2422 PF10337.4 KEY72209.1 - 8.1e-101 338.0 2.3 4.3e-99 332.3 0.5 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KEY72209.1 - 3.5e-54 183.8 0.0 8.9e-54 182.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 KEY72209.1 - 1.3e-08 34.7 14.9 1.3e-08 34.7 10.3 3.8 2 2 2 4 4 4 1 Fusaric acid resistance protein-like ALMT PF11744.3 KEY72209.1 - 0.00024 19.9 8.2 0.00024 19.9 5.7 1.8 2 0 0 2 2 2 1 Aluminium activated malate transporter cobW PF02492.14 KEY72210.1 - 3.1e-42 144.0 6.4 5.2e-31 107.4 0.6 2.2 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KEY72210.1 - 1.4e-17 63.1 0.4 2.3e-13 49.6 0.0 3.0 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain Peptidase_S51 PF03575.12 KEY72210.1 - 2.3e-10 40.4 0.0 6.1e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase family S51 ArgK PF03308.11 KEY72210.1 - 0.00024 19.9 0.1 0.39 9.4 0.0 2.3 2 0 0 2 2 2 2 ArgK protein CbiA PF01656.18 KEY72210.1 - 0.00059 19.2 0.5 0.011 15.2 0.0 2.3 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 KEY72210.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RRN3 PF05327.6 KEY72210.1 - 0.1 10.6 2.8 0.17 9.9 2.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2890 PF11081.3 KEY72210.1 - 0.23 11.4 3.3 0.5 10.4 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Sporozoite_P67 PF05642.6 KEY72210.1 - 0.61 7.8 2.1 0.93 7.2 1.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Peptidase_M14 PF00246.19 KEY72212.1 - 2e-30 106.3 0.2 2.8e-30 105.9 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Ist1 PF03398.9 KEY72213.1 - 0.19 11.1 1.7 0.25 10.7 1.2 1.1 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway HET PF06985.6 KEY72214.1 - 3.3e-34 118.0 0.7 9.9e-34 116.4 0.2 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF3677 PF12432.3 KEY72214.1 - 0.16 12.4 0.1 1.3 9.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3677) CFEM PF05730.6 KEY72216.1 - 0.00085 19.1 1.9 0.0012 18.5 1.3 1.3 1 0 0 1 1 1 1 CFEM domain Uroplakin_II PF07353.7 KEY72216.1 - 0.044 13.1 0.1 6.1 6.1 0.0 2.1 2 0 0 2 2 2 0 Uroplakin II Cellulase PF00150.13 KEY72217.1 - 1.7e-16 60.2 0.1 2.3e-16 59.8 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) adh_short PF00106.20 KEY72218.1 - 7.1e-32 110.6 1.6 1e-31 110.0 1.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY72218.1 - 2e-18 67.0 0.0 2.5e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY72218.1 - 1.7e-13 50.6 0.2 2.5e-13 50.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY72218.1 - 2.7e-07 30.2 0.1 3.9e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY72218.1 - 1.6e-06 28.2 0.4 2.2e-06 27.8 0.3 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KEY72218.1 - 8.4e-05 21.7 0.1 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DUF1776 PF08643.5 KEY72218.1 - 0.00018 20.7 0.0 0.00026 20.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 KEY72218.1 - 0.0022 16.9 0.1 0.0036 16.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.12 KEY72218.1 - 0.0096 16.3 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 KEY72218.1 - 0.055 12.7 0.3 0.089 12.0 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family ADH_zinc_N PF00107.21 KEY72218.1 - 0.071 12.6 0.2 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Fungal_trans PF04082.13 KEY72219.1 - 1.1e-16 60.5 0.0 1.6e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Anticodon_1 PF08264.8 KEY72219.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA peroxidase PF00141.18 KEY72220.1 - 1.1e-87 293.3 0.0 1.6e-45 155.3 0.0 2.2 2 0 0 2 2 2 2 Peroxidase DPPIV_N PF00930.16 KEY72221.1 - 0.027 13.0 0.0 0.41 9.1 0.0 2.2 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Zn_clus PF00172.13 KEY72222.1 - 2.1e-06 27.5 9.5 3.6e-06 26.7 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEY72222.1 - 0.0071 14.9 0.1 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 KEY72223.1 - 2.3e-59 200.6 14.7 2.7e-59 200.3 10.2 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF2975 PF11188.3 KEY72223.1 - 0.012 15.3 7.1 0.012 15.3 4.9 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2975) Glyco_transf_28 PF03033.15 KEY72224.1 - 3.3e-21 75.4 0.1 2.4e-20 72.6 0.1 2.4 2 1 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KEY72224.1 - 0.0012 17.5 0.0 0.002 16.7 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase FAD_binding_4 PF01565.18 KEY72225.1 - 2.1e-20 72.6 3.4 4.2e-20 71.6 1.9 1.9 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.7 KEY72225.1 - 7.3e-10 38.6 0.8 1.5e-09 37.5 0.6 1.5 1 0 0 1 1 1 1 Berberine and berberine like RTA1 PF04479.8 KEY72226.1 - 1.2e-50 172.0 6.2 1.5e-50 171.8 4.3 1.1 1 0 0 1 1 1 1 RTA1 like protein Kei1 PF08552.6 KEY72226.1 - 0.0081 15.8 0.6 0.019 14.6 0.4 1.6 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF308 PF03729.8 KEY72226.1 - 0.022 14.7 1.1 0.022 14.7 0.8 4.1 3 1 1 4 4 4 0 Short repeat of unknown function (DUF308) DUF373 PF04123.8 KEY72226.1 - 7.2 5.5 8.1 3.4 6.6 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Bac_rhamnosid PF05592.6 KEY72227.1 - 7.6e-25 87.0 1.0 1e-21 76.7 0.5 3.9 2 2 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 KEY72227.1 - 8.5e-05 21.4 0.0 0.00015 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Trehalase PF01204.13 KEY72227.1 - 0.0051 15.5 0.0 0.0076 14.9 0.0 1.1 1 0 0 1 1 1 1 Trehalase HET PF06985.6 KEY72228.1 - 8.8e-34 116.6 0.5 1.8e-33 115.6 0.2 1.6 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DIOX_N PF14226.1 KEY72229.1 - 2.7e-08 34.3 0.0 7.1e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KEY72229.1 - 8.9e-08 32.3 0.0 2.1e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.13 KEY72230.1 - 2.4e-09 36.9 7.1 5.2e-09 35.8 4.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.18 KEY72231.1 - 1.2e-16 60.4 4.1 1.2e-16 60.4 2.8 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KEY72231.1 - 7.2e-09 35.4 0.0 2.5e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like Amidohydro_2 PF04909.9 KEY72232.1 - 4.1e-37 128.2 1.5 4.7e-37 128.0 1.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KEY72232.1 - 2.8e-05 24.3 1.3 4.1e-05 23.7 0.9 1.3 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.11 KEY72233.1 - 3.3e-33 114.8 46.1 1.4e-19 70.0 11.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 KEY72234.1 - 9.4e-60 202.4 0.0 1.2e-59 202.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Arch_flagellin PF01917.11 KEY72234.1 - 0.098 12.2 0.3 0.15 11.6 0.2 1.2 1 0 0 1 1 1 0 Archaebacterial flagellin ketoacyl-synt PF00109.21 KEY72235.1 - 5e-71 239.1 0.2 9.5e-71 238.2 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KEY72235.1 - 3.6e-34 117.1 0.3 8e-34 116.0 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KEY72235.1 - 2.4e-32 112.5 0.1 1.4e-30 106.7 0.1 2.4 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 KEY72235.1 - 1.6e-21 76.7 0.0 2.7e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 KEY72235.1 - 3.1e-17 62.5 6.8 3.8e-09 36.6 0.2 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 KEY72235.1 - 4e-13 49.6 0.0 1.1e-12 48.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.8 KEY72235.1 - 3.9e-12 46.2 0.1 2.8e-11 43.4 0.1 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY72235.1 - 4.8e-12 45.8 0.4 2.2e-10 40.4 0.0 2.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Methyltransf_31 PF13847.1 KEY72235.1 - 5.7e-12 45.4 0.0 1.5e-10 40.8 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Peptidase_S9 PF00326.16 KEY72235.1 - 7.6e-11 41.6 0.0 5.9e-08 32.1 0.0 2.6 2 0 0 2 2 2 2 Prolyl oligopeptidase family Methyltransf_23 PF13489.1 KEY72235.1 - 2.2e-08 33.9 0.0 1.7e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY72235.1 - 5.1e-06 27.0 0.0 0.00013 22.5 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain Abhydrolase_6 PF12697.2 KEY72235.1 - 5.9e-06 26.3 0.8 5.9e-06 26.3 0.5 3.1 2 2 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 KEY72235.1 - 2.5e-05 23.4 0.0 5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.7 KEY72235.1 - 0.00012 22.5 0.0 0.0013 19.1 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_PK PF05891.7 KEY72235.1 - 0.00086 18.6 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Abhydrolase_2 PF02230.11 KEY72235.1 - 0.0024 17.3 0.0 0.036 13.4 0.0 2.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase COesterase PF00135.23 KEY72235.1 - 0.0066 15.2 0.0 0.018 13.7 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family DLH PF01738.13 KEY72235.1 - 0.034 13.4 0.0 1.2 8.3 0.0 2.9 3 0 0 3 3 3 0 Dienelactone hydrolase family RrnaAD PF00398.15 KEY72235.1 - 0.09 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_28 PF02636.12 KEY72235.1 - 0.21 10.9 0.0 0.4 10.0 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Trp_DMAT PF11991.3 KEY72236.1 - 3e-92 309.6 0.0 3.5e-92 309.4 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Tannase PF07519.6 KEY72237.1 - 7.4e-79 265.6 0.0 1.1e-78 265.1 0.0 1.3 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 KEY72237.1 - 5.6e-07 29.6 0.0 2.7e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEY72237.1 - 0.00013 21.2 0.1 0.2 10.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KEY72237.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY72237.1 - 0.0019 17.9 0.0 0.13 12.0 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KEY72237.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase NAD_binding_10 PF13460.1 KEY72238.1 - 2.6e-07 30.8 0.0 3.6e-07 30.3 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 KEY72238.1 - 6.2e-05 22.9 0.3 0.00013 21.8 0.0 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 KEY72238.1 - 0.00026 21.2 0.0 0.00045 20.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KEY72238.1 - 0.00083 18.1 0.0 0.001 17.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KEY72238.1 - 0.019 14.4 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KEY72238.1 - 0.051 12.5 0.0 1.4 7.7 0.0 2.3 1 1 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.12 KEY72238.1 - 0.11 11.4 0.0 0.22 10.4 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain Neisseria_TspB PF05616.8 KEY72238.1 - 0.13 10.5 0.0 0.18 10.1 0.0 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Trp_halogenase PF04820.9 KEY72239.1 - 1.1e-27 96.8 0.1 1.1e-12 47.4 0.0 2.6 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 KEY72239.1 - 3.3e-11 42.8 0.0 7.2e-11 41.7 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KEY72239.1 - 1.1e-05 24.7 0.1 2.4e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 KEY72239.1 - 2.3e-05 23.4 0.0 0.00034 19.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEY72239.1 - 2.5e-05 24.2 0.0 4.7e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY72239.1 - 2.8e-05 24.0 1.6 5.8e-05 23.0 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEY72239.1 - 0.0007 18.5 0.4 0.0007 18.5 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 KEY72239.1 - 0.0018 17.1 0.4 0.003 16.4 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 KEY72239.1 - 0.0024 17.0 0.1 0.02 13.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KEY72239.1 - 0.0025 16.3 0.1 0.0038 15.7 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein ThiF PF00899.16 KEY72239.1 - 0.031 14.0 0.2 0.12 12.2 0.2 1.9 2 0 0 2 2 2 0 ThiF family Pyr_redox_3 PF13738.1 KEY72239.1 - 0.039 14.0 0.1 0.08 12.9 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY72239.1 - 0.044 14.1 0.2 0.13 12.7 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RTC PF01137.16 KEY72240.1 - 2e-26 92.2 0.0 3.1e-25 88.2 0.0 2.4 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Pyr_redox_3 PF13738.1 KEY72241.1 - 5.2e-22 78.9 0.0 8.1e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEY72241.1 - 7.9e-19 67.2 0.0 1.3e-16 59.9 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KEY72241.1 - 1.5e-07 30.6 0.0 1.9e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NPR2 PF06218.6 KEY72241.1 - 0.0058 15.3 0.0 0.0084 14.8 0.0 1.1 1 0 0 1 1 1 1 Nitrogen permease regulator 2 Pyr_redox PF00070.22 KEY72241.1 - 0.032 14.6 0.0 0.062 13.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans_2 PF11951.3 KEY72242.1 - 5.2e-25 87.8 1.3 8.1e-25 87.2 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Epimerase PF01370.16 KEY72243.1 - 1.9e-13 50.3 0.1 2.5e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY72243.1 - 2.6e-08 34.0 0.0 3.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KEY72243.1 - 5.3e-06 25.8 0.0 9.8e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KEY72243.1 - 5.9e-05 21.8 0.0 0.00013 20.8 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KEY72243.1 - 0.00014 20.8 0.1 0.00043 19.2 0.1 1.8 1 1 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 KEY72243.1 - 0.0095 16.2 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KEY72243.1 - 0.022 13.7 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase ThuA PF06283.6 KEY72243.1 - 0.096 12.3 0.1 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 Trehalose utilisation DAO PF01266.19 KEY72244.1 - 7.4e-47 159.9 0.1 9.1e-47 159.6 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEY72244.1 - 1.5e-07 30.7 0.7 0.0018 17.2 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 KEY72244.1 - 2.1e-07 30.8 3.5 0.00051 19.8 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KEY72244.1 - 1.9e-05 24.8 0.1 0.0022 18.0 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KEY72244.1 - 2.3e-05 23.2 0.1 0.007 15.0 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 KEY72244.1 - 2.7e-05 24.1 0.0 0.015 15.1 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY72244.1 - 0.00058 19.8 0.0 0.002 18.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KEY72244.1 - 0.018 13.9 0.1 0.6 8.9 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A K_oxygenase PF13434.1 KEY72244.1 - 0.025 13.4 0.0 0.36 9.7 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 KEY72244.1 - 0.026 13.5 0.1 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase GDI PF00996.13 KEY72244.1 - 0.14 10.4 0.0 0.22 9.8 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor DUF2235 PF09994.4 KEY72245.1 - 2.6e-36 125.4 0.0 4.4e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KEY72245.1 - 0.065 12.9 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4078 PF13300.1 KEY72246.1 - 0.05 13.7 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) Antimicrobial13 PF08108.6 KEY72246.1 - 0.13 12.1 0.4 0.25 11.2 0.3 1.4 1 0 0 1 1 1 0 Halocidin family BTB PF00651.26 KEY72247.1 - 0.0016 18.3 0.0 0.0061 16.5 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Sulfatase PF00884.18 KEY72249.1 - 1.6e-44 152.3 0.0 1.8e-42 145.6 0.0 2.2 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KEY72249.1 - 0.018 14.4 0.0 0.038 13.3 0.0 1.4 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase ADH_zinc_N PF00107.21 KEY72249.1 - 0.024 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Chitin_bind_3 PF03067.10 KEY72250.1 - 1.2e-07 32.2 0.0 1.3e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Chitin binding domain Methyltransf_2 PF00891.13 KEY72251.1 - 1.8e-26 92.8 0.0 2.9e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase HTH_IclR PF09339.5 KEY72251.1 - 5.3e-05 22.7 0.4 0.00014 21.3 0.3 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain Methyltransf_23 PF13489.1 KEY72251.1 - 0.00016 21.4 0.0 0.00036 20.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.6 KEY72251.1 - 0.00019 21.1 0.5 0.0006 19.5 0.3 1.9 1 0 0 1 1 1 1 Dimerisation domain Rrf2 PF02082.15 KEY72251.1 - 0.012 15.7 0.0 0.037 14.1 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.14 KEY72251.1 - 0.055 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 KEY72251.1 - 0.078 12.6 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 MarR family Acetyltransf_1 PF00583.19 KEY72251.1 - 0.096 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family PQ-loop PF04193.9 KEY72252.1 - 4.3e-09 35.7 7.6 2.3e-05 23.8 0.5 3.3 4 0 0 4 4 4 2 PQ loop repeat DUF1440 PF07274.7 KEY72252.1 - 0.0029 17.5 0.6 0.0058 16.6 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1440) MtN3_slv PF03083.11 KEY72252.1 - 0.41 10.5 0.1 0.41 10.5 0.1 3.3 3 1 1 4 4 4 0 Sugar efflux transporter for intercellular exchange Aminotran_3 PF00202.16 KEY72253.1 - 4.1e-98 328.3 0.0 4.9e-98 328.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aldedh PF00171.17 KEY72254.1 - 3.5e-166 553.1 0.1 3.9e-166 552.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.11 KEY72255.1 - 1.2e-34 119.6 21.5 1.6e-34 119.2 14.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KEY72255.1 - 0.0013 18.2 2.9 0.0013 18.2 2.0 2.5 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 p450 PF00067.17 KEY72256.1 - 2.2e-63 214.3 0.0 2.6e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_18 PF12847.2 KEY72257.1 - 3.9e-14 53.1 0.0 6.4e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY72257.1 - 8.5e-14 51.3 0.0 1.1e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY72257.1 - 2e-10 41.0 0.0 3.2e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY72257.1 - 6.9e-10 39.3 0.0 1.1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY72257.1 - 1e-09 38.2 0.0 1.6e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY72257.1 - 2.3e-09 37.3 0.0 3.5e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY72257.1 - 1.7e-08 34.7 0.0 3.3e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY72257.1 - 2.7e-06 26.8 0.0 4.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KEY72257.1 - 5.6e-05 22.3 0.0 8.5e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Cons_hypoth95 PF03602.10 KEY72257.1 - 9.4e-05 21.8 0.0 0.0021 17.4 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_PK PF05891.7 KEY72257.1 - 0.00036 19.8 0.0 0.00058 19.2 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PrmA PF06325.8 KEY72257.1 - 0.0043 16.2 0.0 0.0063 15.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.1 KEY72257.1 - 0.0056 17.4 0.0 0.011 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KEY72257.1 - 0.0084 15.2 0.0 0.01 14.9 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Spermine_synth PF01564.12 KEY72257.1 - 0.014 14.3 0.0 0.027 13.4 0.0 1.4 1 0 0 1 1 1 0 Spermine/spermidine synthase Methyltransf_3 PF01596.12 KEY72257.1 - 0.031 13.3 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase NodS PF05401.6 KEY72257.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) ketoacyl-synt PF00109.21 KEY72258.1 - 1.1e-66 224.9 0.0 1.8e-66 224.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KEY72258.1 - 7.3e-57 191.9 0.0 2.5e-56 190.2 0.0 2.0 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KEY72258.1 - 8.3e-48 163.3 0.0 1.5e-47 162.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KEY72258.1 - 1.8e-44 151.6 0.0 8.6e-44 149.3 0.0 2.4 1 0 0 1 1 1 1 short chain dehydrogenase PS-DH PF14765.1 KEY72258.1 - 2e-38 132.2 0.0 4.9e-38 130.9 0.0 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KEY72258.1 - 1.7e-37 127.8 0.0 4.5e-37 126.5 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KEY72258.1 - 2.6e-19 69.0 0.0 1.7e-18 66.3 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 KEY72258.1 - 7.8e-10 38.8 0.1 7e-09 35.8 0.0 2.7 3 0 0 3 3 3 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 KEY72258.1 - 1.5e-08 34.5 0.0 4.9e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY72258.1 - 4e-07 30.4 0.0 1.2e-06 28.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KEY72258.1 - 1.8e-06 28.9 0.0 8.3e-06 26.7 0.0 2.3 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 KEY72258.1 - 0.00081 19.0 0.0 0.0031 17.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY72258.1 - 0.0055 17.2 0.0 0.025 15.1 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY72258.1 - 0.017 15.6 0.0 0.053 14.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain ADH_N PF08240.7 KEY72258.1 - 0.026 14.2 0.0 0.082 12.6 0.0 1.9 2 0 0 2 2 1 0 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 KEY72258.1 - 0.037 13.1 0.0 0.3 10.1 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Aminotran_1_2 PF00155.16 KEY72259.1 - 1.2e-26 93.5 0.0 1.5e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.15 KEY72259.1 - 0.002 16.7 0.1 0.0049 15.4 0.0 1.7 2 0 0 2 2 2 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.15 KEY72259.1 - 0.0025 16.1 0.0 0.0043 15.3 0.0 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Sulfotransfer_3 PF13469.1 KEY72260.1 - 2.9e-06 28.2 0.3 5.8e-06 27.3 0.2 1.5 1 1 0 1 1 1 1 Sulfotransferase family K_oxygenase PF13434.1 KEY72260.1 - 0.0077 15.1 0.2 0.011 14.7 0.1 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) MFS_1 PF07690.11 KEY72261.1 - 1.9e-37 128.8 14.3 1.9e-37 128.8 9.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily HET PF06985.6 KEY72262.1 - 9.6e-30 103.5 0.1 1.6e-29 102.8 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4003 PF13170.1 KEY72262.1 - 0.078 12.2 0.0 0.7 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4003) Glyco_hydro_6 PF01341.12 KEY72263.1 - 2.6e-91 306.1 0.0 3.1e-91 305.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Pectinesterase PF01095.14 KEY72263.1 - 0.22 10.0 0.1 0.33 9.4 0.0 1.1 1 0 0 1 1 1 0 Pectinesterase MFS_1 PF07690.11 KEY72264.1 - 3.4e-18 65.4 11.6 4.7e-18 65.0 7.6 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily FMN_dh PF01070.13 KEY72265.1 - 2.7e-103 345.5 0.0 3.1e-103 345.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KEY72265.1 - 0.0026 16.7 0.1 0.0038 16.2 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KEY72265.1 - 0.0026 16.6 0.2 0.0049 15.7 0.1 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 KEY72265.1 - 0.016 14.4 0.2 0.074 12.3 0.1 1.9 1 1 1 2 2 2 0 Histidine biosynthesis protein LuxQ-periplasm PF09308.5 KEY72265.1 - 0.074 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 LuxQ, periplasmic MFS_1 PF07690.11 KEY72267.1 - 1.4e-25 89.8 51.2 1.4e-25 89.8 35.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KEY72267.1 - 9.8e-07 27.5 38.7 0.00017 20.1 11.3 2.6 1 1 1 2 2 2 2 MFS/sugar transport protein N2227 PF07942.7 KEY72267.1 - 0.12 11.2 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein Exo_endo_phos PF03372.18 KEY72268.1 - 9.6e-09 35.5 0.1 1.4e-08 34.9 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Skp1_POZ PF03931.10 KEY72268.1 - 0.051 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain DUF4246 PF14033.1 KEY72270.1 - 1.1e-177 591.7 0.3 1.4e-177 591.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_3 PF13640.1 KEY72270.1 - 0.0017 18.8 0.0 0.0052 17.2 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 KEY72270.1 - 0.0077 16.5 0.0 0.024 14.9 0.0 1.8 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Fungal_trans_2 PF11951.3 KEY72271.1 - 2.7e-07 29.5 0.3 4.1e-07 28.9 0.1 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 KEY72272.1 - 4.4e-11 42.9 0.4 1e-10 41.7 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY72272.1 - 1.3e-06 28.3 0.1 2.2e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY72272.1 - 0.001 18.7 0.3 0.0016 18.1 0.2 1.2 1 0 0 1 1 1 1 KR domain FAD_binding_3 PF01494.14 KEY72273.1 - 1.9e-73 247.5 0.1 2.3e-72 244.0 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KEY72273.1 - 2.3e-22 79.4 0.0 4.1e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.19 KEY72273.1 - 6.3e-06 25.2 1.2 5.6e-05 22.1 0.4 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KEY72273.1 - 6e-05 22.1 0.6 0.00014 20.8 0.3 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KEY72273.1 - 0.00018 20.6 0.0 0.00033 19.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KEY72273.1 - 0.00027 20.8 0.2 0.0006 19.7 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEY72273.1 - 0.00027 19.9 0.1 0.00044 19.2 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KEY72273.1 - 0.00037 20.4 0.2 0.001 19.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KEY72273.1 - 0.005 15.3 0.2 0.008 14.6 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 KEY72273.1 - 0.0064 15.6 1.0 0.011 14.8 0.7 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEY72273.1 - 0.013 15.5 0.4 0.036 14.1 0.3 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY72273.1 - 0.016 14.1 0.1 0.025 13.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein ThiF PF00899.16 KEY72273.1 - 0.03 14.1 0.1 0.059 13.1 0.1 1.4 1 0 0 1 1 1 0 ThiF family AlaDh_PNT_C PF01262.16 KEY72273.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Cellulase PF00150.13 KEY72274.1 - 8.1e-18 64.6 0.0 1.1e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KEY72274.1 - 4e-11 42.3 14.8 1.6e-10 40.4 10.2 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Cellulase-like PF12876.2 KEY72274.1 - 0.00014 22.2 0.0 0.00058 20.2 0.0 2.0 2 0 0 2 2 2 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 KEY72274.1 - 0.012 14.5 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 KEY72274.1 - 0.019 14.1 0.1 0.03 13.4 0.1 1.2 1 0 0 1 1 1 0 Beta-galactosidase Glyco_hydro_10 PF00331.15 KEY72274.1 - 0.15 11.0 0.0 0.3 10.0 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 10 Toxin_7 PF05980.7 KEY72274.1 - 0.64 10.1 3.0 1.8 8.6 2.1 1.7 1 0 0 1 1 1 0 Toxin 7 Fungal_trans PF04082.13 KEY72275.1 - 4.4e-28 97.8 0.0 7.2e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY72275.1 - 2e-06 27.5 13.8 3.6e-06 26.7 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TEX19 PF15553.1 KEY72275.1 - 0.1 12.4 4.0 3.6 7.4 0.2 2.6 2 0 0 2 2 2 0 Testis-expressed protein 19 DUF3938 PF13074.1 KEY72276.1 - 0.019 14.8 0.3 0.04 13.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) BCLP PF12304.3 KEY72276.1 - 0.059 12.7 0.7 0.11 11.9 0.5 1.4 1 0 0 1 1 1 0 Beta-casein like protein p450 PF00067.17 KEY72277.1 - 5e-41 140.7 0.0 6.2e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GST_C PF00043.20 KEY72278.1 - 9.8e-11 41.5 0.0 1.6e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEY72278.1 - 4.4e-08 33.4 0.0 7.5e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KEY72278.1 - 2.1e-07 30.7 0.1 4e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KEY72278.1 - 2.2e-07 30.9 0.0 4.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KEY72278.1 - 1.9e-06 28.0 0.0 3.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEY72278.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain adh_short PF00106.20 KEY72279.1 - 4.4e-14 52.7 0.6 6.5e-14 52.1 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY72279.1 - 9.4e-09 35.1 0.6 1.7e-08 34.3 0.4 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KEY72280.1 - 8.8e-13 48.6 0.0 1.2e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KEY72280.1 - 1.3e-07 31.1 0.1 1.8e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KEY72280.1 - 0.00097 17.9 0.0 0.0013 17.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KEY72280.1 - 0.0054 15.6 0.0 0.0081 15.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KEY72280.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_Gly3P_dh_N PF01210.18 KEY72280.1 - 0.14 11.9 0.1 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF4243 PF14027.1 KEY72281.1 - 4.7e-79 266.2 0.8 5.7e-79 265.9 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) AMP-binding PF00501.23 KEY72282.1 - 5.4e-59 199.6 0.0 6.9e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF1772 PF08592.6 KEY72283.1 - 2.1e-21 76.1 11.1 2.9e-21 75.6 7.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) EthD PF07110.6 KEY72284.1 - 1.3e-21 77.3 0.5 1.7e-21 76.9 0.4 1.1 1 0 0 1 1 1 1 EthD domain Scytalone_dh PF02982.9 KEY72285.1 - 1.9e-66 222.5 2.6 2.3e-66 222.2 1.8 1.1 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 KEY72285.1 - 1.5e-09 37.8 2.9 2e-09 37.4 2.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 KEY72285.1 - 0.13 12.2 4.3 2.8 8.0 3.0 2.4 1 1 0 1 1 1 0 SnoaL-like domain GMC_oxred_N PF00732.14 KEY72286.1 - 1.6e-44 152.2 0.0 2.3e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY72286.1 - 3.7e-32 111.5 0.0 5.9e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 KEY72286.1 - 3.3e-06 27.1 0.0 0.0036 17.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEY72286.1 - 1.1e-05 24.5 0.7 9.8e-05 21.4 0.5 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY72286.1 - 1.6e-05 24.8 0.0 5e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEY72286.1 - 0.00029 20.9 0.0 0.17 11.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY72286.1 - 0.00038 19.4 0.0 0.0011 17.9 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 KEY72286.1 - 0.0016 16.9 0.0 0.014 13.9 0.0 2.3 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_9 PF13454.1 KEY72286.1 - 0.0041 16.9 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KEY72286.1 - 0.005 15.5 0.0 0.027 13.0 0.0 1.9 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.12 KEY72286.1 - 0.012 14.6 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KEY72286.1 - 0.036 14.4 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEY72286.1 - 0.11 11.4 0.1 0.31 10.0 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Aldo_ket_red PF00248.16 KEY72287.1 - 8.5e-57 192.1 0.0 9.6e-57 191.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ketoacyl-synt PF00109.21 KEY72288.1 - 4.3e-71 239.3 0.1 4.3e-71 239.3 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEY72288.1 - 4e-42 144.6 0.0 1.1e-41 143.2 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KEY72288.1 - 1.2e-30 105.8 2.8 1.2e-30 105.8 1.9 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KEY72288.1 - 2.5e-11 43.6 0.1 7.6e-11 42.1 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KEY72288.1 - 0.00058 18.9 0.0 0.0014 17.6 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Lactamase_B PF00753.22 KEY72289.1 - 6.3e-24 84.6 1.9 8.2e-24 84.3 1.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KEY72289.1 - 2.5e-05 23.8 0.8 4.6e-05 23.0 0.6 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Trp_DMAT PF11991.3 KEY72290.1 - 1.2e-84 284.5 0.0 1.7e-84 284.0 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase AflR PF08493.5 KEY72291.1 - 7.1e-14 51.4 1.4 7.1e-14 51.4 1.0 1.9 2 0 0 2 2 2 1 Aflatoxin regulatory protein Zn_clus PF00172.13 KEY72291.1 - 3.8e-08 33.0 11.8 6e-08 32.4 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KEY72292.1 - 3.9e-29 101.7 0.4 6.1e-29 101.0 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY72292.1 - 4.9e-27 95.2 0.0 6e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY72292.1 - 4.2e-13 49.3 0.4 6.1e-13 48.8 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY72292.1 - 0.0073 15.7 0.6 0.086 12.2 0.2 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KEY72292.1 - 0.086 12.6 0.3 0.19 11.5 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KEY72292.1 - 0.1 11.6 0.1 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.5 KEY72292.1 - 0.12 11.4 0.0 0.14 11.2 0.0 1.3 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) ABC2_membrane PF01061.19 KEY72295.1 - 2.2e-78 262.2 57.6 3.3e-41 140.7 11.5 3.1 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 KEY72295.1 - 1e-36 126.2 0.0 1.1e-17 64.6 0.0 3.4 3 1 1 4 4 4 2 ABC transporter PDR_CDR PF06422.7 KEY72295.1 - 4.3e-35 119.4 4.9 6.2e-31 106.1 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 KEY72295.1 - 9.1e-16 57.7 0.0 2.5e-15 56.3 0.0 1.8 1 1 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 KEY72295.1 - 5.7e-10 38.7 38.6 3.3e-07 29.6 9.0 2.8 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.1 KEY72295.1 - 1.8e-07 30.7 0.0 0.0003 20.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KEY72295.1 - 8.9e-07 28.8 0.0 0.059 13.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KEY72295.1 - 1.3e-05 24.4 0.0 0.0035 16.5 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KEY72295.1 - 4.2e-05 23.5 0.3 0.095 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KEY72295.1 - 7e-05 22.2 0.2 0.031 13.8 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KEY72295.1 - 0.00024 21.4 0.0 0.058 13.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEY72295.1 - 0.00051 20.8 1.0 0.64 10.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 KEY72295.1 - 0.001 19.2 0.1 0.71 10.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEY72295.1 - 0.001 18.7 0.1 3 7.6 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain cobW PF02492.14 KEY72295.1 - 0.0012 18.3 0.1 0.098 12.0 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 KEY72295.1 - 0.0061 16.2 0.0 2.1 8.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 KEY72295.1 - 0.0076 16.2 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KEY72295.1 - 0.0078 15.4 0.0 0.61 9.2 0.0 3.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA PF00004.24 KEY72295.1 - 0.026 14.7 0.0 12 6.1 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 KEY72295.1 - 0.12 12.3 0.1 1.4 8.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain UPF0079 PF02367.12 KEY72295.1 - 0.25 10.9 0.5 3.9 7.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ABC2_membrane_2 PF12679.2 KEY72295.1 - 4.3 6.1 17.0 0.07 11.9 2.9 3.1 3 0 0 3 3 3 0 ABC-2 family transporter protein adh_short PF00106.20 KEY72296.1 - 9.4e-18 64.6 0.7 1.6e-17 63.8 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY72296.1 - 9.3e-10 38.4 0.5 1.5e-09 37.8 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY72296.1 - 9e-05 22.0 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Peripla_BP_6 PF13458.1 KEY72296.1 - 0.0098 15.2 0.5 0.017 14.4 0.4 1.4 1 1 0 1 1 1 1 Periplasmic binding protein ERp29_N PF07912.8 KEY72296.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 ERp29, N-terminal domain Fungal_trans PF04082.13 KEY72297.1 - 1.4e-13 50.3 0.5 2.1e-13 49.7 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY72297.1 - 3.9e-08 33.0 12.1 7.3e-08 32.1 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KfrA_N PF11740.3 KEY72297.1 - 2.3 8.6 4.9 6.1 7.3 0.6 2.4 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term MFS_1 PF07690.11 KEY72298.1 - 6e-36 123.8 34.4 2.5e-35 121.8 23.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEY72298.1 - 0.0017 16.8 15.6 0.0027 16.1 10.8 1.4 1 0 0 1 1 1 1 MFS/sugar transport protein ESSS PF10183.4 KEY72298.1 - 0.012 15.9 0.9 0.056 13.8 0.6 2.2 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MFS_1 PF07690.11 KEY72300.1 - 5.3e-38 130.6 52.5 5.3e-38 130.6 36.4 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF1418 PF07214.7 KEY72300.1 - 0.23 11.1 2.3 0.65 9.6 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1418) Cutinase PF01083.17 KEY72302.1 - 5.6e-44 150.0 0.0 7.9e-44 149.5 0.0 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KEY72302.1 - 7.2e-05 22.3 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.11 KEY72302.1 - 0.05 13.0 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KEY72302.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family VirJ PF06057.6 KEY72302.1 - 0.082 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Mucin PF01456.12 KEY72302.1 - 0.24 11.1 14.8 0.4 10.4 10.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.6 KEY72302.1 - 0.33 10.7 7.7 0.54 10.0 5.3 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) SSP160 PF06933.6 KEY72302.1 - 0.58 8.0 11.7 0.84 7.5 8.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PUA PF01472.15 KEY72305.1 - 4.1e-12 45.6 0.1 9e-06 25.3 0.0 2.3 2 0 0 2 2 2 2 PUA domain Inhibitor_I78 PF11720.3 KEY72306.1 - 1.7e-11 43.6 0.0 2.1e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 KEY72306.1 - 0.0047 17.0 0.1 0.0067 16.5 0.1 1.4 1 1 0 1 1 1 1 Potato inhibitor I family NST1 PF13945.1 KEY72308.1 - 2.8e-51 174.3 11.6 2.8e-51 174.3 8.0 5.4 2 2 2 5 5 5 1 Salt tolerance down-regulator Ras PF00071.17 KEY72309.1 - 1e-49 168.0 0.0 1.2e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEY72309.1 - 6.5e-16 58.8 0.0 9.2e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEY72309.1 - 5.3e-06 25.7 0.0 8.1e-06 25.1 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEY72309.1 - 0.0075 15.4 0.0 0.0099 15.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KEY72309.1 - 0.022 14.0 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KEY72309.1 - 0.025 14.0 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 KEY72309.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.1 KEY72309.1 - 0.15 11.9 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain MRP-L28 PF09812.4 KEY72310.1 - 0.00027 20.7 0.2 0.0004 20.2 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 ADP_ribosyl_GH PF03747.9 KEY72311.1 - 3.2e-61 207.6 0.2 3.8e-61 207.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Rick_17kDa_Anti PF05433.10 KEY72311.1 - 0.42 10.3 7.8 2.7 7.7 0.1 2.9 3 0 0 3 3 3 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 KEY72311.1 - 3 7.5 7.0 13 5.4 0.1 3.0 3 0 0 3 3 3 0 Glycine zipper Lipase_GDSL PF00657.17 KEY72312.1 - 2.9e-13 50.1 1.8 7.4e-13 48.8 1.2 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KEY72312.1 - 1.6e-12 47.9 1.3 2.2e-12 47.4 0.9 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family RRM_6 PF14259.1 KEY72314.1 - 0.17 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FAD_binding_2 PF00890.19 KEY72316.1 - 2.3e-96 323.2 0.5 2.6e-96 323.0 0.3 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KEY72316.1 - 1.3e-07 31.4 0.0 6e-07 29.3 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KEY72316.1 - 2.2e-05 23.7 0.0 3.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEY72316.1 - 3.9e-05 22.7 1.4 9.8e-05 21.4 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEY72316.1 - 0.00018 21.4 0.0 0.0021 17.9 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEY72316.1 - 0.00025 19.6 3.3 0.0029 16.1 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 KEY72316.1 - 0.00028 19.8 0.1 0.00058 18.8 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 KEY72316.1 - 0.00037 19.6 0.1 0.0013 17.8 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 KEY72316.1 - 0.00072 19.6 0.1 0.0015 18.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEY72316.1 - 0.0016 18.2 1.8 0.0035 17.1 0.1 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KEY72316.1 - 0.0045 15.9 0.1 0.0071 15.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 KEY72316.1 - 0.0054 15.8 0.0 0.0082 15.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase MFS_1 PF07690.11 KEY72317.1 - 7.3e-16 57.8 17.9 7.3e-16 57.8 12.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sulfotransfer_3 PF13469.1 KEY72318.1 - 4.1e-06 27.8 0.7 6.5e-06 27.1 0.5 1.6 1 1 0 1 1 1 1 Sulfotransferase family 2-Hacid_dh_C PF02826.14 KEY72318.1 - 0.18 10.9 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase PF00069.20 KEY72320.1 - 1.6e-55 188.0 0.0 2.3e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY72320.1 - 6e-27 94.3 0.0 7.1e-26 90.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KEY72320.1 - 0.00091 18.3 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KEY72320.1 - 0.0012 17.9 0.0 0.79 8.6 0.0 3.0 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 KEY72320.1 - 0.0055 16.4 0.0 0.0098 15.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family UL11 PF11094.3 KEY72320.1 - 0.025 14.3 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 Membrane-associated tegument protein Pox_ser-thr_kin PF05445.6 KEY72320.1 - 0.031 13.0 0.1 0.056 12.2 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 KEY72320.1 - 0.065 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 KEY72320.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 KEY72322.1 - 5.4e-54 183.0 0.1 7.5e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY72322.1 - 2.4e-25 89.1 0.1 8.5e-25 87.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 KEY72322.1 - 0.0085 15.4 0.0 0.026 13.8 0.0 1.8 1 0 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.6 KEY72322.1 - 0.017 13.9 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 KEY72322.1 - 0.022 13.7 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like TMA7 PF09072.5 KEY72323.1 - 1.5e-27 95.7 17.2 1.7e-27 95.6 11.9 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 LptE PF04390.7 KEY72323.1 - 0.13 12.0 0.1 0.14 11.8 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide-assembly OCC1 PF15506.1 KEY72323.1 - 0.67 9.8 2.8 1.1 9.1 0.1 2.0 2 0 0 2 2 2 0 OCC1 family HlyIII PF03006.15 KEY72324.1 - 1.9e-62 210.5 16.2 2.3e-62 210.3 11.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF2583 PF10762.4 KEY72324.1 - 0.037 14.1 0.7 0.11 12.6 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) DUF2723 PF11028.3 KEY72324.1 - 0.064 12.7 0.5 0.064 12.7 0.3 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2723) Ycf66_N PF07444.6 KEY72324.1 - 0.093 12.4 3.8 2.4 7.9 0.1 3.3 2 1 2 4 4 4 0 Ycf66 protein N-terminus DUF3325 PF11804.3 KEY72324.1 - 6.4 6.7 10.8 0.12 12.3 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) DUF4131 PF13567.1 KEY72324.1 - 8.3 5.7 13.1 0.35 10.2 0.5 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) WD40 PF00400.27 KEY72325.1 - 0.00013 21.7 5.5 10 6.1 0.0 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_3 PF13570.1 KEY72325.1 - 0.049 13.9 0.3 9.9 6.5 0.0 2.8 2 0 0 2 2 2 0 PQQ-like domain SnoaL_2 PF12680.2 KEY72326.1 - 1.3e-09 38.4 0.0 1.7e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 KEY72326.1 - 0.0043 16.9 0.0 0.0075 16.1 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like domain Glyco_hydro_61 PF03443.9 KEY72327.1 - 1.4e-50 172.1 0.0 2.3e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Med3 PF11593.3 KEY72327.1 - 0.98 8.5 12.6 1.2 8.2 8.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Apc3 PF12895.2 KEY72328.1 - 0.0049 16.9 0.0 0.015 15.3 0.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 adh_short PF00106.20 KEY72329.1 - 2.7e-34 118.5 0.4 4e-34 117.9 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY72329.1 - 7e-26 91.4 0.1 1.3e-25 90.5 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY72329.1 - 2e-17 63.4 0.1 2.8e-17 62.9 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KEY72329.1 - 0.0017 18.0 0.3 0.0029 17.2 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KEY72329.1 - 0.014 14.7 0.4 0.027 13.8 0.3 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AdoHcyase_NAD PF00670.16 KEY72329.1 - 0.032 14.0 0.5 0.095 12.5 0.1 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Glycos_transf_2 PF00535.21 KEY72330.1 - 3.8e-33 114.5 0.0 4.6e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KEY72330.1 - 2e-14 53.9 0.0 4.7e-14 52.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KEY72330.1 - 1.5e-08 34.0 0.0 2.1e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KEY72330.1 - 3.9e-05 23.0 0.0 5.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.1 KEY72330.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 2 DUF221 PF02714.10 KEY72332.1 - 1.4e-95 319.8 15.1 2.2e-95 319.2 10.5 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KEY72332.1 - 1.1e-38 132.2 4.1 2.7e-38 131.0 2.8 1.7 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KEY72332.1 - 6.5e-17 61.8 0.1 1.3e-16 60.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) AATase PF07247.7 KEY72333.1 - 4.4e-21 74.9 0.0 9.6e-21 73.8 0.0 1.5 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KEY72333.1 - 0.00026 19.9 0.3 0.00056 18.8 0.0 1.6 2 1 0 2 2 2 1 Condensation domain WES_acyltransf PF03007.11 KEY72333.1 - 0.0071 15.9 0.5 0.015 14.8 0.1 1.7 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain UQ_con PF00179.21 KEY72334.1 - 2.3e-37 127.5 0.0 3.9e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEY72334.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B Nop52 PF05997.7 KEY72335.1 - 3.6e-47 160.6 0.0 4.3e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 ABC_cobalt PF09819.4 KEY72335.1 - 0.068 13.1 0.0 0.095 12.6 0.0 1.2 1 0 0 1 1 1 0 ABC-type cobalt transport system, permease component RabGAP-TBC PF00566.13 KEY72336.1 - 3.7e-34 118.0 0.1 1e-16 61.0 0.0 3.7 4 0 0 4 4 4 3 Rab-GTPase-TBC domain Plasmodium_Vir PF05795.6 KEY72337.1 - 2.2 7.3 8.7 2.7 7.0 6.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TP53IP5 PF15331.1 KEY72337.1 - 4.5 7.1 7.4 6.7 6.5 5.1 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 HLH PF00010.21 KEY72338.1 - 6.7e-09 35.3 0.0 1.3e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HIT PF01230.18 KEY72339.1 - 7.3e-17 61.7 0.0 1.2e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KEY72339.1 - 3.4e-06 27.2 0.0 6.8e-06 26.2 0.0 1.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KEY72339.1 - 0.035 13.7 0.0 0.086 12.4 0.0 1.6 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 Strep_his_triad PF04270.8 KEY72339.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Streptococcal histidine triad protein DNA_RNApol_7kD PF03604.8 KEY72340.1 - 1.1e-09 37.5 1.1 1.7e-09 36.9 0.8 1.3 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.5 KEY72340.1 - 0.0035 17.2 1.5 0.011 15.7 1.0 1.8 1 1 0 1 1 1 1 Zinc ribbon domain Prok-RING_1 PF14446.1 KEY72340.1 - 0.0058 16.3 0.4 0.0077 15.9 0.3 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 HypA PF01155.14 KEY72340.1 - 0.0061 16.2 0.1 0.007 16.0 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family PhnA_Zn_Ribbon PF08274.7 KEY72340.1 - 0.011 15.5 0.5 0.017 14.9 0.3 1.3 1 0 0 1 1 1 0 PhnA Zinc-Ribbon DnaJ_CXXCXGXG PF00684.14 KEY72340.1 - 0.013 15.4 0.2 0.016 15.2 0.1 1.4 1 0 0 1 1 1 0 DnaJ central domain zf-RING_3 PF14369.1 KEY72340.1 - 0.018 15.0 1.1 0.043 13.8 0.7 1.6 1 1 1 2 2 2 0 zinc-finger Zn_Tnp_IS1595 PF12760.2 KEY72340.1 - 0.027 14.2 2.6 0.3 10.9 0.2 2.1 1 1 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.2 KEY72340.1 - 0.036 13.8 0.2 0.05 13.4 0.1 1.2 1 0 0 1 1 1 0 Double zinc ribbon DUF329 PF03884.9 KEY72340.1 - 0.052 13.0 0.3 2.2 7.9 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF329) TF_Zn_Ribbon PF08271.7 KEY72340.1 - 0.062 12.6 0.5 1.9 7.8 0.1 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding Lar_restr_allev PF14354.1 KEY72340.1 - 0.065 13.5 1.1 2.7 8.3 0.1 2.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar A2L_zn_ribbon PF08792.5 KEY72340.1 - 0.07 12.6 0.5 0.13 11.7 0.3 1.5 1 1 0 1 1 1 0 A2L zinc ribbon domain zf-TFIIB PF13453.1 KEY72340.1 - 0.085 12.0 0.7 5.9 6.1 0.1 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-ISL3 PF14690.1 KEY72340.1 - 0.097 12.7 0.4 0.9 9.6 0.0 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_ribbon_recom PF13408.1 KEY72340.1 - 0.16 12.2 3.2 1.6 9.0 0.3 2.4 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain PADR1 PF08063.7 KEY72340.1 - 0.2 11.0 1.0 1.3 8.4 0.0 2.0 1 1 1 2 2 2 0 PADR1 (NUC008) domain Auto_anti-p27 PF06677.7 KEY72340.1 - 0.23 11.2 1.6 0.4 10.4 0.9 1.5 1 1 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF35_N PF12172.3 KEY72340.1 - 0.87 9.5 3.7 9.3 6.3 0.2 2.4 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) ATP_bind_1 PF03029.12 KEY72341.1 - 7e-66 222.1 0.0 8.6e-66 221.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KEY72341.1 - 0.019 14.3 0.0 0.065 12.6 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain CbiA PF01656.18 KEY72341.1 - 0.034 13.5 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FeoB_N PF02421.13 KEY72341.1 - 0.08 12.2 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B ChAPs PF09295.5 KEY72342.1 - 1.3e-156 521.3 0.0 1.3e-156 521.3 0.0 1.4 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 KEY72342.1 - 1.8e-06 27.4 0.1 0.067 12.8 0.0 3.2 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.1 KEY72342.1 - 9.6e-06 25.8 0.2 0.64 10.8 0.1 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEY72342.1 - 1.4e-05 24.5 0.3 0.24 11.3 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEY72342.1 - 5.3e-05 22.6 0.0 0.062 13.1 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEY72342.1 - 0.0004 20.0 1.4 0.032 14.1 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KEY72342.1 - 0.00041 20.1 0.9 0.045 13.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEY72342.1 - 0.0031 17.0 0.3 1.4 8.6 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEY72342.1 - 0.025 15.0 0.0 8 7.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 KEY72342.1 - 0.029 13.4 3.1 0.08 11.9 0.3 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEY72342.1 - 0.059 13.3 0.1 8.7 6.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat FTCD PF02971.9 KEY72342.1 - 0.092 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Formiminotransferase domain TPR_16 PF13432.1 KEY72342.1 - 0.12 13.0 0.2 10 6.9 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KEY72343.1 - 0.0048 16.9 0.1 18 5.8 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat GTP_cyclohydroI PF01227.17 KEY72344.1 - 1.2e-71 239.7 0.1 1.5e-71 239.4 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KEY72344.1 - 0.00076 19.3 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein DegT_DnrJ_EryC1 PF01041.12 KEY72344.1 - 0.058 12.4 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Hepatitis_core PF00906.15 KEY72344.1 - 4.3 6.9 8.9 7.5 6.1 6.2 1.3 1 0 0 1 1 1 0 Hepatitis core antigen DEAD PF00270.24 KEY72345.1 - 5.8e-45 152.8 0.0 9e-45 152.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY72345.1 - 1e-26 92.5 0.0 2.1e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEY72345.1 - 0.0013 18.5 0.0 0.009 15.8 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Brix PF04427.13 KEY72346.1 - 2.4e-55 187.1 0.0 3.4e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain PP2C PF00481.16 KEY72346.1 - 1.4e-30 106.5 0.0 3e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C BLVR PF06375.6 KEY72346.1 - 0.00018 21.3 5.6 0.19 11.5 6.2 3.4 3 0 0 3 3 3 1 Bovine leukaemia virus receptor (BLVR) SpoIIE PF07228.7 KEY72346.1 - 0.00074 19.2 0.2 0.32 10.6 0.0 3.2 1 1 1 2 2 2 2 Stage II sporulation protein E (SpoIIE) TT_ORF2 PF02957.10 KEY72346.1 - 1.3 9.7 7.2 5.8 7.6 5.0 2.2 1 0 0 1 1 1 0 TT viral ORF2 TFIIB PF00382.14 KEY72347.1 - 5.5e-30 102.9 0.7 7.7e-19 67.2 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 KEY72347.1 - 1.4e-20 73.3 1.2 1.4e-20 73.3 0.9 2.8 3 0 0 3 3 3 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 KEY72347.1 - 1.2e-05 24.8 0.4 0.01 15.3 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Herpes_capsid PF06112.6 KEY72347.1 - 0.15 12.1 2.5 0.27 11.2 0.2 2.3 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein DUF1349 PF07081.6 KEY72348.1 - 7.2e-15 54.8 0.0 1.8e-14 53.5 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) NADH_dh_m_C1 PF15088.1 KEY72348.1 - 0.0037 16.7 0.1 0.014 14.9 0.0 1.9 2 0 0 2 2 2 1 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial BTB PF00651.26 KEY72349.1 - 4.8e-07 29.7 0.0 1.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 KEY72349.1 - 0.001 19.1 0.0 0.1 12.6 0.0 2.4 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain EI24 PF07264.6 KEY72350.1 - 0.071 12.5 0.2 0.071 12.5 0.1 2.3 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) RCC1_2 PF13540.1 KEY72350.1 - 0.39 10.4 2.1 0.77 9.4 1.5 1.5 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat zf-DHHC PF01529.15 KEY72350.1 - 0.56 9.5 3.0 9.1 5.6 0.1 2.5 2 1 0 2 2 2 0 DHHC palmitoyltransferase Sigma_reg_N PF13800.1 KEY72350.1 - 0.57 10.2 2.9 1.2 9.2 0.0 2.8 3 0 0 3 3 3 0 Sigma factor regulator N-terminal CsbD PF05532.7 KEY72351.1 - 4.9e-09 35.7 12.2 6.9e-05 22.4 1.9 2.1 1 1 1 2 2 2 2 CsbD-like Peptidase_S24 PF00717.18 KEY72352.1 - 1.2e-08 34.4 0.1 1.9e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like Claudin_2 PF13903.1 KEY72353.1 - 0.19 11.3 8.9 0.61 9.7 1.2 2.2 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Kinesin PF00225.18 KEY72354.1 - 9.3e-55 185.6 0.0 3.5e-54 183.7 0.0 2.0 1 1 1 2 2 2 1 Kinesin motor domain Herpes_BLRF2 PF05812.7 KEY72354.1 - 0.0027 17.4 4.5 0.03 14.1 0.2 2.6 2 0 0 2 2 2 2 Herpesvirus BLRF2 protein Jnk-SapK_ap_N PF09744.4 KEY72354.1 - 4.3 7.2 12.5 51 3.8 8.6 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 FTZ PF03867.9 KEY72355.1 - 0.13 11.5 4.8 2.6 7.2 0.1 2.5 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region DEAD PF00270.24 KEY72356.1 - 6.2e-11 42.0 0.2 6.5e-10 38.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 KEY72356.1 - 1.5e-08 34.4 0.0 3.6e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KEY72356.1 - 9.4e-07 28.6 0.0 2.1e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KEY72356.1 - 1.5e-05 25.1 0.1 3.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain HA2 PF04408.18 KEY72356.1 - 1.9e-05 24.6 0.0 4.3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_RecD PF05127.9 KEY72356.1 - 0.052 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Helicase ResIII PF04851.10 KEY72356.1 - 0.092 12.5 0.0 3 7.6 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RRM_5 PF13893.1 KEY72357.1 - 0.0013 18.5 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEY72357.1 - 0.0036 16.9 0.0 0.0073 15.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY72357.1 - 0.091 12.7 0.0 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CwfJ_C_1 PF04677.10 KEY72358.1 - 2e-24 85.5 0.0 3e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KEY72358.1 - 1.5e-20 73.5 0.0 4.8e-20 71.8 0.0 2.0 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Abhydrolase_6 PF12697.2 KEY72359.1 - 1.6e-20 73.9 1.1 8.5e-20 71.6 0.8 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY72359.1 - 1.2e-08 34.7 0.0 0.0064 16.2 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY72359.1 - 2.7e-07 30.4 0.0 4.7e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 KEY72359.1 - 0.14 11.4 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family FA_hydroxylase PF04116.8 KEY72360.1 - 0.00059 20.2 8.1 0.00059 20.2 5.6 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3808 PF10300.4 KEY72361.1 - 2.2e-117 392.4 0.0 3e-117 392.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DSS1_SEM1 PF05160.8 KEY72363.1 - 3e-23 81.3 16.9 4e-23 80.9 11.7 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family S_layer_N PF05123.7 KEY72363.1 - 0.15 11.6 1.3 0.16 11.5 0.9 1.1 1 0 0 1 1 1 0 S-layer like family, N-terminal region PGK PF00162.14 KEY72364.1 - 2.1e-153 510.4 0.5 2.4e-153 510.2 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Peripla_BP_4 PF13407.1 KEY72364.1 - 0.011 15.1 2.0 0.017 14.4 0.9 1.7 2 0 0 2 2 2 0 Periplasmic binding protein domain PrpR_N PF06506.6 KEY72364.1 - 0.079 12.3 0.1 7.1 5.9 0.1 3.3 3 1 1 4 4 4 0 Propionate catabolism activator FIVAR PF07554.8 KEY72364.1 - 1.3 9.3 8.0 7 6.9 0.0 4.2 5 0 0 5 5 5 0 Uncharacterised Sugar-binding Domain Mpv17_PMP22 PF04117.7 KEY72365.1 - 9.3e-24 82.8 0.4 2.8e-23 81.3 0.2 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family NMD3 PF04981.8 KEY72366.1 - 1.3e-68 230.6 2.8 1.7e-68 230.2 1.9 1.2 1 0 0 1 1 1 1 NMD3 family DUF35_N PF12172.3 KEY72366.1 - 0.36 10.8 0.1 0.36 10.8 0.1 2.8 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) FYVE PF01363.16 KEY72366.1 - 1.9 8.4 8.3 17 5.4 2.6 2.4 2 0 0 2 2 2 0 FYVE zinc finger DZR PF12773.2 KEY72366.1 - 2.5 7.9 9.7 27 4.6 4.9 2.7 2 1 0 2 2 2 0 Double zinc ribbon PAN_4 PF14295.1 KEY72368.1 - 0.048 13.3 3.9 0.084 12.5 2.7 1.4 1 0 0 1 1 1 0 PAN domain DUF4470 PF14737.1 KEY72369.1 - 1.2e-19 69.8 0.0 2.2e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.1 KEY72369.1 - 9.1e-18 63.6 2.3 3e-14 52.4 0.2 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KEY72369.1 - 1.4e-09 37.1 4.8 0.00051 19.7 1.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEY72369.1 - 2.4e-08 34.4 1.3 8.6e-08 32.6 0.9 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEY72369.1 - 2.6e-06 26.7 2.9 0.00046 19.6 0.5 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEY72369.1 - 1.5e-05 25.1 3.1 0.1 13.3 0.3 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 KEY72369.1 - 3e-05 23.7 2.0 0.00038 20.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEY72369.1 - 5.1e-05 23.1 3.7 0.0022 17.8 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEY72369.1 - 0.00083 19.6 5.2 0.0052 17.1 0.4 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 KEY72369.1 - 0.0016 18.5 2.5 0.0031 17.6 0.2 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KEY72369.1 - 0.0045 16.6 0.4 0.35 10.7 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEY72369.1 - 0.017 15.2 0.2 0.12 12.6 0.0 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEY72369.1 - 0.019 14.7 1.0 0.9 9.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 KEY72369.1 - 0.09 12.6 0.1 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat ABC_membrane PF00664.18 KEY72370.1 - 1.1e-52 179.2 29.1 4.1e-27 95.2 11.7 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 KEY72370.1 - 1.7e-49 167.6 0.0 1.8e-29 102.8 0.0 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KEY72370.1 - 2.5e-08 33.4 0.1 0.0095 15.1 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEY72370.1 - 9.5e-08 32.3 0.2 0.45 10.4 0.0 4.1 3 1 0 3 3 3 2 AAA domain Miro PF08477.8 KEY72370.1 - 2e-06 28.2 0.2 0.052 14.0 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 KEY72370.1 - 2.9e-06 27.3 0.2 0.048 13.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KEY72370.1 - 5.4e-06 25.8 0.8 0.019 14.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KEY72370.1 - 6.2e-06 26.1 0.2 0.028 14.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 KEY72370.1 - 0.00022 21.6 2.8 0.3 11.3 0.1 2.7 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 KEY72370.1 - 0.00027 20.1 2.6 0.37 9.8 0.1 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_10 PF12846.2 KEY72370.1 - 0.00028 20.4 0.1 0.099 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 KEY72370.1 - 0.00032 21.5 0.2 0.72 10.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KEY72370.1 - 0.00032 20.4 0.6 0.74 9.5 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KEY72370.1 - 0.00055 19.3 0.4 0.57 9.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 KEY72370.1 - 0.00066 19.5 2.1 0.025 14.4 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 DUF258 PF03193.11 KEY72370.1 - 0.001 18.2 0.4 0.94 8.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KEY72370.1 - 0.0016 18.3 2.0 0.063 13.0 0.2 2.5 2 0 0 2 2 2 1 Dynamin family TrwB_AAD_bind PF10412.4 KEY72370.1 - 0.0016 17.1 0.9 0.22 10.0 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 KEY72370.1 - 0.0026 16.7 0.0 0.26 10.1 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF815 PF05673.8 KEY72370.1 - 0.0046 15.9 0.2 0.37 9.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ArgK PF03308.11 KEY72370.1 - 0.0067 15.2 2.1 0.028 13.1 0.3 2.2 2 0 0 2 2 2 1 ArgK protein AAA_22 PF13401.1 KEY72370.1 - 0.0075 16.4 0.1 7 6.8 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KEY72370.1 - 0.008 15.7 1.0 1 8.9 0.1 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KEY72370.1 - 0.011 15.1 3.9 0.11 11.8 0.1 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 KEY72370.1 - 0.014 14.8 0.0 6 6.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.1 KEY72370.1 - 0.05 13.9 0.1 17 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KEY72370.1 - 0.06 13.5 0.1 7.5 6.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KEY72370.1 - 0.093 11.5 1.3 8.9 5.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain GTP_EFTU PF00009.22 KEY72370.1 - 0.1 12.0 0.1 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NACHT PF05729.7 KEY72370.1 - 0.12 12.0 1.9 0.78 9.3 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.1 KEY72370.1 - 0.14 11.2 0.0 8.4 5.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.12 KEY72370.1 - 0.18 11.3 3.0 9.7 5.6 0.1 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DPPIV_N PF00930.16 KEY72372.1 - 5.9e-101 337.5 0.2 8.9e-101 336.9 0.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KEY72372.1 - 1.4e-35 122.4 0.7 2.6e-35 121.6 0.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KEY72372.1 - 7.3e-07 29.2 0.0 1.9e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY72372.1 - 2.4e-06 27.3 0.0 5.6e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KEY72372.1 - 0.0035 16.9 0.0 0.0083 15.7 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 KEY72372.1 - 0.18 11.4 0.0 0.74 9.4 0.0 1.8 1 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Cerato-platanin PF07249.7 KEY72373.1 - 0.0002 21.3 0.8 0.0005 20.0 0.1 1.8 2 0 0 2 2 2 1 Cerato-platanin Epimerase PF01370.16 KEY72376.1 - 2.1e-36 125.5 0.0 3.2e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Na_Ca_ex PF01699.19 KEY72376.1 - 7.5e-26 90.4 30.4 4.6e-16 58.6 8.6 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein NAD_binding_4 PF07993.7 KEY72376.1 - 1e-06 27.8 0.0 0.00016 20.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 KEY72376.1 - 2.2e-06 26.5 0.0 4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KEY72376.1 - 0.083 11.7 0.0 1.4 7.7 0.0 2.2 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Turandot PF07240.6 KEY72376.1 - 0.18 11.2 0.0 0.52 9.8 0.0 1.7 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot Epimerase_Csub PF13950.1 KEY72376.1 - 0.19 11.7 0.0 0.49 10.3 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit Glyco_hydro_88 PF07470.8 KEY72377.1 - 2.9e-63 213.9 3.8 3.7e-63 213.5 2.7 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Lipase_GDSL PF00657.17 KEY72378.1 - 2.6e-12 47.0 0.0 3.9e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KEY72378.1 - 1.3e-11 44.9 0.2 2.1e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF1680 PF07944.7 KEY72379.1 - 8.5e-132 440.0 0.0 9.8e-132 439.8 0.0 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Ank_2 PF12796.2 KEY72380.1 - 2e-49 165.8 0.1 1.3e-19 70.2 0.0 9.5 4 2 5 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.25 KEY72380.1 - 4.3e-40 133.5 14.3 2.5e-08 33.3 0.1 12.1 12 0 0 12 12 12 6 Ankyrin repeat Ank_3 PF13606.1 KEY72380.1 - 8.4e-31 102.9 9.8 1.4e-05 24.8 0.0 10.8 12 0 0 12 12 12 6 Ankyrin repeat Ank_4 PF13637.1 KEY72380.1 - 1.9e-28 98.2 5.8 1.8e-09 37.8 0.0 9.2 8 3 1 9 9 9 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY72380.1 - 3.7e-25 87.3 8.7 7.6e-09 35.5 0.0 8.5 8 2 2 10 10 10 4 Ankyrin repeats (many copies) DUF3046 PF11248.3 KEY72380.1 - 0.089 12.7 0.1 0.49 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3046) CppA_N PF14506.1 KEY72380.1 - 0.22 11.2 0.0 0.51 10.0 0.0 1.6 1 0 0 1 1 1 0 CppA N-terminal Glyco_hydro_43 PF04616.9 KEY72381.1 - 1.1e-10 41.1 4.1 1.4e-09 37.4 1.0 1.7 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Beta_helix PF13229.1 KEY72382.1 - 1.6e-12 47.4 30.4 8.7e-10 38.5 8.5 3.2 2 1 1 3 3 3 2 Right handed beta helix region Chondroitinas_B PF14592.1 KEY72382.1 - 3.4e-05 22.8 0.0 0.0001 21.2 0.0 1.8 1 0 0 1 1 1 1 Chondroitinase B DUF1565 PF07602.6 KEY72382.1 - 0.0094 15.1 0.5 0.0094 15.1 0.4 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1565) Dehydratase_LU PF02286.10 KEY72382.1 - 0.041 12.1 0.1 0.065 11.4 0.0 1.2 1 0 0 1 1 1 0 Dehydratase large subunit SNF2_N PF00176.18 KEY72384.1 - 3.8e-07 29.2 0.0 4.4e-07 28.9 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KEY72384.1 - 0.0042 16.9 0.0 0.0046 16.8 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KEY72384.1 - 0.0076 15.2 0.0 0.0076 15.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Nucleoplasmin PF03066.10 KEY72385.1 - 0.031 13.7 6.4 0.035 13.6 4.4 1.1 1 0 0 1 1 1 0 Nucleoplasmin Cwf_Cwc_15 PF04889.7 KEY72385.1 - 0.48 10.0 8.9 0.53 9.9 6.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF688 PF05097.7 KEY72385.1 - 0.86 8.4 6.2 1.1 8.1 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) RXT2_N PF08595.6 KEY72385.1 - 0.99 9.1 7.2 1.2 8.8 5.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Tom22 PF04281.8 KEY72385.1 - 1.4 8.4 4.4 1.8 8.0 3.0 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Sigma70_ner PF04546.8 KEY72385.1 - 2.4 7.7 8.3 3 7.3 5.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region MFS_1 PF07690.11 KEY72388.1 - 3.7e-29 101.5 30.2 6e-29 100.8 20.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily NIR_SIR PF01077.17 KEY72389.1 - 9.9e-31 106.2 0.1 1.7e-30 105.4 0.1 1.3 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 KEY72389.1 - 1.4e-24 87.0 0.0 2.8e-23 82.8 0.0 3.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 KEY72389.1 - 1.8e-14 53.5 1.6 1.4e-11 44.2 1.4 2.6 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Pyr_redox PF00070.22 KEY72389.1 - 7.5e-14 51.9 3.5 8.5e-14 51.7 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 KEY72389.1 - 2.7e-11 43.0 0.0 5.9e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NIR_SIR_ferr PF03460.12 KEY72389.1 - 4.3e-09 35.8 0.0 1.1e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.21 KEY72389.1 - 6.3e-09 35.2 0.0 1.7e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_9 PF13454.1 KEY72389.1 - 0.00015 21.5 0.2 6.4 6.5 0.0 3.4 2 1 1 3 3 3 3 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KEY72389.1 - 0.00047 20.2 0.5 0.12 12.4 0.1 3.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEY72389.1 - 0.01 14.7 2.7 0.17 10.6 0.0 2.9 1 1 2 3 3 3 0 FAD binding domain TrkA_N PF02254.13 KEY72389.1 - 0.044 13.7 0.9 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 TrkA-N domain Oxidored_molyb PF00174.14 KEY72390.1 - 4.6e-52 175.8 0.0 7.9e-52 175.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KEY72390.1 - 5.1e-46 155.5 0.1 8.8e-46 154.7 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.16 KEY72390.1 - 6.6e-28 97.4 0.0 1.7e-27 96.1 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KEY72390.1 - 1.1e-22 79.9 0.0 3.4e-22 78.4 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 KEY72390.1 - 1.8e-20 72.5 0.0 3.3e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KEY72390.1 - 0.008 16.0 0.0 0.029 14.2 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Terpene_synth_C PF03936.11 KEY72391.1 - 0.00021 20.5 0.1 0.00032 20.0 0.1 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain FlgD_ig PF13860.1 KEY72391.1 - 0.084 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 FlgD Ig-like domain Peptidase_M6 PF05547.6 KEY72392.1 - 2.6e-08 32.3 0.4 0.00011 20.4 0.3 2.1 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 bZIP_1 PF00170.16 KEY72393.1 - 2.5e-09 36.9 8.0 4e-09 36.3 5.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KEY72393.1 - 9.8e-06 25.3 8.3 1.6e-05 24.6 5.7 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KEY72393.1 - 0.00015 22.0 8.3 0.00022 21.4 5.8 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF3860 PF12976.2 KEY72394.1 - 0.1 12.4 3.2 0.57 10.0 0.1 3.1 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3860) Barttin PF15462.1 KEY72394.1 - 0.65 9.6 5.5 0.22 11.1 0.4 2.2 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Pectate_lyase PF03211.8 KEY72395.1 - 6.2e-75 251.2 4.9 9.5e-75 250.6 3.4 1.3 1 0 0 1 1 1 1 Pectate lyase 4HBT_3 PF13622.1 KEY72396.1 - 1.9e-33 116.2 0.0 3.1e-33 115.6 0.0 1.4 1 1 0 1 1 1 1 Thioesterase-like superfamily DUF4449 PF14613.1 KEY72397.1 - 0.00013 21.9 0.0 0.00054 19.9 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) NADPH_Ox PF08414.5 KEY72397.1 - 0.013 15.6 0.4 0.41 10.7 0.0 2.6 1 1 1 2 2 2 0 Respiratory burst NADPH oxidase Latrophilin PF02354.11 KEY72397.1 - 0.017 13.8 1.1 0.043 12.5 0.4 1.8 2 0 0 2 2 2 0 Latrophilin Cytoplasmic C-terminal region F5_F8_type_C PF00754.20 KEY72398.1 - 1e-21 77.0 0.2 3.6e-21 75.3 0.1 2.0 1 0 0 1 1 1 1 F5/8 type C domain DUF1929 PF09118.6 KEY72398.1 - 2.4e-21 75.6 1.4 5.4e-21 74.5 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.1 KEY72398.1 - 2.3e-16 59.1 5.6 4.4e-07 29.7 0.0 5.0 5 1 1 6 6 5 3 Kelch motif Kelch_4 PF13418.1 KEY72398.1 - 7.9e-15 54.3 9.1 5.8e-05 22.7 0.0 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 KEY72398.1 - 7e-13 47.8 0.2 0.0017 17.8 0.1 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.1 KEY72398.1 - 8.9e-11 41.6 9.7 0.0065 16.6 0.1 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.6 KEY72398.1 - 1.2e-09 37.5 0.1 5.6e-05 22.3 0.1 2.4 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_2 PF07646.10 KEY72398.1 - 4.2e-05 23.1 0.6 0.44 10.3 0.1 4.0 3 1 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 KEY72398.1 - 0.031 14.2 1.4 13 5.8 0.1 3.3 3 0 0 3 3 3 0 Kelch motif Mitoc_L55 PF09776.4 KEY72398.1 - 0.082 12.4 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 RCC1_2 PF13540.1 KEY72398.1 - 0.11 12.1 2.3 5.7 6.6 0.1 3.7 4 0 0 4 4 4 0 Regulator of chromosome condensation (RCC1) repeat Secretin PF00263.16 KEY72398.1 - 0.36 10.1 2.5 4 6.7 0.0 3.1 4 0 0 4 4 4 0 Bacterial type II and III secretion system protein MFS_1 PF07690.11 KEY72399.1 - 4.2e-34 117.8 19.0 1.9e-27 95.9 3.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY72399.1 - 6.8e-13 47.9 0.0 6.8e-13 47.9 0.0 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 KEY72399.1 - 9.3e-05 20.9 3.4 9.3e-05 20.9 2.4 3.4 3 1 1 4 4 4 2 MFS/sugar transport protein MFS_3 PF05977.8 KEY72399.1 - 0.00071 17.8 6.3 0.017 13.2 1.3 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector Vac7 PF12751.2 KEY72399.1 - 0.15 10.8 0.2 0.23 10.2 0.1 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Tmemb_9 PF05434.6 KEY72399.1 - 0.32 10.7 0.9 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 TMEM9 Peptidase_M28 PF04389.12 KEY72401.1 - 2.1e-36 125.3 0.0 3.6e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KEY72401.1 - 2.5e-12 46.3 0.0 5e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 PA domain adh_short PF00106.20 KEY72402.1 - 3.5e-15 56.2 0.1 5.6e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY72402.1 - 1.7e-05 24.5 0.1 3.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY72402.1 - 3.5e-05 23.7 0.0 6.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 KEY72402.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.13 KEY72403.1 - 1.2e-10 40.6 0.0 5e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY72403.1 - 0.0014 18.5 8.0 0.0026 17.6 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 KEY72404.1 - 1.4e-19 70.4 0.0 3.3e-19 69.1 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEY72404.1 - 0.011 14.6 1.6 0.39 9.5 0.4 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEY72404.1 - 0.015 15.1 0.1 0.18 11.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY72404.1 - 0.017 14.0 0.3 1.7 7.4 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 KEY72404.1 - 0.019 14.9 0.0 0.069 13.1 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF3275 PF11679.3 KEY72405.1 - 0.0028 17.3 2.3 0.0036 16.9 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3275) Pec_lyase_C PF00544.14 KEY72406.1 - 5.8e-41 140.1 7.9 5.8e-41 140.1 5.5 1.8 2 1 0 2 2 2 1 Pectate lyase Pyr_redox_2 PF07992.9 KEY72407.1 - 5.2e-08 33.0 0.0 1.8e-07 31.2 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY72407.1 - 0.00016 21.8 0.1 0.017 15.2 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEY72407.1 - 0.0015 18.3 0.0 0.018 14.8 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KEY72407.1 - 0.0041 16.0 0.2 0.015 14.2 0.1 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase DUF822 PF05687.8 KEY72407.1 - 0.03 14.6 0.0 0.051 13.9 0.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Lycopene_cycl PF05834.7 KEY72407.1 - 0.11 11.4 0.4 0.44 9.4 0.1 2.0 2 1 0 2 2 2 0 Lycopene cyclase protein Malic_M PF03949.10 KEY72407.1 - 0.13 11.8 0.0 0.41 10.1 0.0 1.7 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Molybdopterin PF00384.17 KEY72408.1 - 8.2e-69 232.3 0.0 1.2e-68 231.8 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.16 KEY72408.1 - 8.7e-25 86.6 1.0 1.5e-24 85.9 0.0 1.9 2 0 0 2 2 2 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.11 KEY72408.1 - 2.7e-13 49.4 1.1 4.5e-13 48.7 0.2 1.8 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain DUF977 PF06163.6 KEY72408.1 - 0.031 14.0 0.0 0.089 12.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) MoCF_biosynth PF00994.19 KEY72409.1 - 3.8e-29 100.9 0.0 7.7e-29 99.9 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_N PF03453.12 KEY72409.1 - 2e-25 89.0 0.0 4.2e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 KEY72409.1 - 0.019 14.8 0.0 0.052 13.5 0.0 1.7 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) Glyco_hydro_43 PF04616.9 KEY72410.1 - 1.8e-21 76.4 5.4 2.9e-08 33.1 0.0 4.0 3 1 0 3 3 3 3 Glycosyl hydrolases family 43 MFS_1 PF07690.11 KEY72411.1 - 5.9e-40 137.0 32.5 5.9e-40 137.0 22.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY72411.1 - 5.2e-19 68.1 17.9 1.2e-18 66.9 12.4 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter K_oxygenase PF13434.1 KEY72412.1 - 5e-15 55.2 0.0 4.1e-08 32.5 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KEY72412.1 - 2.7e-09 37.3 0.0 0.00032 20.8 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEY72412.1 - 3.4e-06 27.0 0.0 0.0022 17.9 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEY72412.1 - 0.00015 21.6 0.8 0.019 14.7 0.5 2.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.9 KEY72412.1 - 0.00026 19.5 0.0 0.03 12.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.14 KEY72412.1 - 0.00032 19.8 1.5 0.0076 15.3 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 KEY72412.1 - 0.0013 17.6 0.1 0.033 13.0 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.19 KEY72412.1 - 0.002 17.0 2.3 1.4 7.7 0.0 2.9 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY72412.1 - 0.0058 16.6 0.2 0.036 14.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KEY72412.1 - 0.0061 15.6 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KEY72412.1 - 0.012 16.0 0.1 11 6.5 0.0 3.7 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY72412.1 - 0.018 13.9 0.0 0.037 12.9 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 KEY72412.1 - 0.13 11.0 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Peptidase_M28 PF04389.12 KEY72413.1 - 2.9e-16 59.7 0.0 7e-16 58.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 KEY72413.1 - 4.4e-16 58.5 0.0 7.2e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 KEY72413.1 - 0.00079 19.0 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 KEY72413.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.5 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 Glyco_hydro_3 PF00933.16 KEY72414.1 - 1e-50 172.4 0.0 1.4e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY72414.1 - 1.6e-08 34.3 0.0 7.3e-07 28.9 0.0 2.3 1 1 1 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain DUF1690 PF07956.6 KEY72414.1 - 0.00012 22.0 0.0 0.0002 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) DUF4066 PF13278.1 KEY72415.1 - 4.6e-23 81.3 0.0 8.9e-23 80.3 0.0 1.6 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KEY72415.1 - 4e-10 39.3 0.0 1.8e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 DJ-1/PfpI family FAD_binding_4 PF01565.18 KEY72417.1 - 2e-18 66.2 0.9 3.7e-18 65.3 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY72417.1 - 0.028 14.3 0.1 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like Tyrosinase PF00264.15 KEY72418.1 - 4.4e-44 151.2 0.3 6.1e-44 150.8 0.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Hydrophobin_2 PF06766.6 KEY72419.1 - 7.2e-27 92.8 9.1 9e-27 92.5 6.3 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Na_H_Exchanger PF00999.16 KEY72420.1 - 6.5e-38 130.2 25.9 9e-38 129.7 17.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3632 PF12311.3 KEY72421.1 - 0.00011 22.0 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) OHCU_decarbox PF09349.5 KEY72424.1 - 3.8e-38 131.2 0.0 4.3e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase Prp19 PF08606.6 KEY72425.1 - 1.3e-31 108.1 2.1 2.8e-31 107.0 1.4 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 KEY72425.1 - 9e-17 60.2 0.4 0.00086 19.1 0.0 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat zf-Nse PF11789.3 KEY72425.1 - 0.015 14.7 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Lactonase PF10282.4 KEY72425.1 - 0.024 13.7 0.0 0.14 11.1 0.0 2.2 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller U-box PF04564.10 KEY72425.1 - 0.075 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 U-box domain zf-C3HC4 PF00097.20 KEY72426.1 - 0.0094 15.5 0.3 0.024 14.3 0.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEY72426.1 - 0.0095 15.9 0.5 0.0095 15.9 0.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY72426.1 - 0.018 14.7 5.8 0.088 12.5 4.1 2.0 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KEY72426.1 - 0.053 13.1 2.7 0.13 11.9 0.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KEY72426.1 - 0.083 12.7 1.4 0.33 10.8 0.1 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FYVE PF01363.16 KEY72426.1 - 0.21 11.4 2.7 0.71 9.8 1.9 1.9 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_UBOX PF13445.1 KEY72426.1 - 0.25 11.0 1.1 0.37 10.5 0.1 1.7 2 0 0 2 2 2 0 RING-type zinc-finger Metallothio_Pro PF02069.11 KEY72426.1 - 0.34 10.7 4.5 5.8 6.8 0.3 2.3 2 0 0 2 2 2 0 Prokaryotic metallothionein Prok-RING_4 PF14447.1 KEY72426.1 - 0.66 9.5 4.4 0.47 10.0 1.0 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.1 KEY72426.1 - 0.92 9.3 5.7 7.9 6.3 4.0 2.2 1 1 0 1 1 1 0 Ring finger domain Aldo_ket_red PF00248.16 KEY72427.1 - 6.1e-40 136.8 0.0 1.5e-39 135.5 0.0 1.6 2 0 0 2 2 2 1 Aldo/keto reductase family CAF-1_p150 PF11600.3 KEY72427.1 - 0.0029 17.0 10.9 0.0029 17.0 7.5 3.2 2 1 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal eRF1_1 PF03463.10 KEY72428.1 - 1.5e-35 121.6 0.0 2.5e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 KEY72428.1 - 6.3e-24 84.8 0.1 1e-23 84.1 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KEY72428.1 - 4.8e-15 55.8 0.0 9e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 WD40 PF00400.27 KEY72429.1 - 2.6e-31 106.3 7.3 1.7e-10 40.3 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat Zn-ribbon_8 PF09723.5 KEY72429.1 - 0.077 12.9 1.7 0.18 11.7 1.2 1.6 1 0 0 1 1 1 0 Zinc ribbon domain BBS2_Mid PF14783.1 KEY72429.1 - 0.24 11.1 0.1 62 3.4 0.0 3.9 4 2 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region OrfB_Zn_ribbon PF07282.6 KEY72429.1 - 0.56 9.9 2.1 1.2 8.8 1.5 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Thioredoxin PF00085.15 KEY72430.1 - 6e-20 70.8 0.0 7.9e-20 70.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 KEY72430.1 - 9.8e-06 25.1 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KEY72430.1 - 0.00011 22.3 0.0 0.0025 17.9 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KEY72430.1 - 0.026 14.6 0.0 0.11 12.6 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_7 PF13899.1 KEY72430.1 - 0.028 14.4 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like WD40 PF00400.27 KEY72431.1 - 2e-29 100.3 7.8 1.2e-10 40.8 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KEY72431.1 - 1.3e-17 63.3 0.0 3.1e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex SBP_bac_11 PF13531.1 KEY72432.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Fungal_trans PF04082.13 KEY72433.1 - 1.2e-15 57.0 0.0 2e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY72433.1 - 1.4e-08 34.5 9.6 2.4e-08 33.7 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactonase PF10282.4 KEY72434.1 - 3.2e-48 164.5 0.0 4.8e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF1513 PF07433.6 KEY72434.1 - 0.02 13.8 0.0 0.043 12.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Glyco_hydro_16 PF00722.16 KEY72435.1 - 3.5e-41 140.5 0.4 5.4e-41 139.9 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Nucleoplasmin PF03066.10 KEY72435.1 - 0.0047 16.4 8.8 0.008 15.7 6.1 1.3 1 0 0 1 1 1 1 Nucleoplasmin Prothymosin PF03247.9 KEY72435.1 - 0.0067 16.5 13.1 0.013 15.6 9.1 1.5 1 0 0 1 1 1 1 Prothymosin/parathymosin family CDC45 PF02724.9 KEY72435.1 - 0.04 11.9 6.1 0.056 11.4 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.6 KEY72435.1 - 0.091 12.5 6.1 0.17 11.6 4.2 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Sigma70_ner PF04546.8 KEY72435.1 - 0.17 11.4 7.9 0.28 10.7 5.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region EBV-NA3 PF05009.7 KEY72435.1 - 0.46 9.6 4.5 0.72 9.0 3.1 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) RXT2_N PF08595.6 KEY72435.1 - 0.5 10.1 6.4 0.83 9.4 4.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Paf1 PF03985.8 KEY72435.1 - 0.58 8.8 4.5 0.86 8.2 3.1 1.2 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.7 KEY72435.1 - 0.71 7.7 9.1 0.89 7.3 6.3 1.1 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.1 KEY72435.1 - 0.86 9.9 13.4 1.8 8.9 9.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Daxx PF03344.10 KEY72435.1 - 1.2 7.5 12.3 1.5 7.2 8.5 1.1 1 0 0 1 1 1 0 Daxx Family FAM176 PF14851.1 KEY72435.1 - 2.2 7.9 4.7 4.3 6.9 3.3 1.5 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.5 KEY72435.1 - 2.9 8.1 20.4 7.4 6.8 14.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.4 KEY72435.1 - 3.3 6.3 20.6 4.5 5.8 14.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 KEY72435.1 - 5 6.3 13.2 7 5.8 9.2 1.2 1 0 0 1 1 1 0 SDA1 eIF-3c_N PF05470.7 KEY72435.1 - 6.9 4.6 6.7 9.5 4.1 4.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PPP4R2 PF09184.6 KEY72435.1 - 9.4 5.6 11.8 19 4.6 8.2 1.4 1 0 0 1 1 1 0 PPP4R2 Myc_N PF01056.13 KEY72435.1 - 9.6 5.2 9.1 6 5.9 4.8 1.8 2 0 0 2 2 2 0 Myc amino-terminal region DEAD PF00270.24 KEY72436.1 - 9.7e-40 135.8 0.1 2e-39 134.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY72436.1 - 8.6e-23 79.9 0.1 1.2e-12 47.4 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KEY72436.1 - 5.3e-06 26.3 0.1 3.4e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDC45 PF02724.9 KEY72436.1 - 0.011 13.8 0.4 0.014 13.4 0.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Myb_DNA-binding PF00249.26 KEY72437.1 - 9.1e-14 51.2 2.9 1.4e-07 31.4 0.7 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEY72437.1 - 1.9e-11 43.8 0.5 9.6e-06 25.6 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_38 PF13936.1 KEY72437.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain PAT1 PF09770.4 KEY72437.1 - 0.41 8.8 29.2 0.45 8.6 20.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Myb_DNA-bind_6 PF13921.1 KEY72439.1 - 9.3e-05 22.4 0.0 0.0013 18.7 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KEY72439.1 - 0.069 13.2 0.5 0.26 11.3 0.3 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain ILVD_EDD PF00920.16 KEY72440.1 - 2.1e-196 653.3 2.4 2.5e-196 653.1 1.6 1.0 1 0 0 1 1 1 1 Dehydratase family PX PF00787.19 KEY72441.1 - 6.7e-19 67.7 0.3 1.3e-18 66.8 0.2 1.5 1 0 0 1 1 1 1 PX domain Ribosomal_L18e PF00828.14 KEY72442.1 - 3.8e-18 66.1 0.1 7.6e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Glyco_transf_15 PF01793.11 KEY72443.1 - 1.2e-130 435.3 0.2 1.5e-130 434.9 0.1 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4604 PF15377.1 KEY72444.1 - 1.4e-27 96.8 19.4 1.5e-27 96.7 13.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF2201_N PF13203.1 KEY72444.1 - 4.1 6.5 8.2 4.9 6.2 5.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain COX5B PF01215.14 KEY72445.1 - 4.7e-35 120.2 0.0 7.1e-35 119.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.14 KEY72445.1 - 0.012 15.0 0.4 3.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger CTNNB1_binding PF08347.6 KEY72445.1 - 0.046 13.9 0.0 0.066 13.4 0.0 1.2 1 0 0 1 1 1 0 N-terminal CTNNB1 binding SnoaL_2 PF12680.2 KEY72446.1 - 0.00077 19.8 0.0 0.0015 18.9 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 KEY72446.1 - 0.11 12.0 0.1 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase Fructosamin_kin PF03881.9 KEY72447.1 - 4.1e-27 94.8 0.0 5.4e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KEY72447.1 - 0.0019 17.9 0.1 0.0022 17.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ank_2 PF12796.2 KEY72448.1 - 9.6e-23 80.3 1.7 2.2e-09 37.5 0.0 5.0 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KEY72448.1 - 1.2e-14 53.2 6.1 0.0026 17.4 0.0 7.3 7 1 1 8 8 8 3 Ankyrin repeat Ank_4 PF13637.1 KEY72448.1 - 4.2e-13 49.4 1.3 0.0028 18.1 0.0 6.7 4 3 3 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY72448.1 - 3.4e-09 36.0 3.6 0.32 11.3 0.0 7.3 8 1 1 9 9 9 3 Ankyrin repeat Ank_5 PF13857.1 KEY72448.1 - 4.4e-07 29.9 3.3 0.0025 17.9 0.1 5.3 3 2 1 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEY72449.1 - 2.9e-35 120.4 1.3 3.2e-14 53.0 0.0 4.1 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEY72449.1 - 2e-22 77.0 8.2 2e-05 24.4 0.1 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.25 KEY72449.1 - 1.2e-21 75.3 12.0 1.1e-05 25.0 0.0 6.0 6 1 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 KEY72449.1 - 1.3e-13 50.9 6.7 5.2e-06 26.8 0.0 5.5 5 2 2 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY72449.1 - 7e-13 48.3 8.2 0.0026 17.9 0.0 5.6 4 1 2 6 6 6 5 Ankyrin repeats (many copies) F-box PF00646.28 KEY72449.1 - 0.006 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KEY72449.1 - 0.051 13.3 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 F-box-like Asp PF00026.18 KEY72450.1 - 1.2e-55 189.0 0.0 1.4e-55 188.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEY72450.1 - 2e-11 44.1 0.3 9.1e-11 41.9 0.0 2.2 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KEY72450.1 - 1.7e-05 25.2 0.0 0.0052 17.2 0.0 3.2 2 1 0 2 2 2 1 Aspartyl protease Uds1 PF15456.1 KEY72451.1 - 1.3e-28 99.4 6.1 1.5e-28 99.3 4.3 1.0 1 0 0 1 1 1 1 Up-regulated During Septation DUF904 PF06005.7 KEY72451.1 - 0.0017 18.5 0.3 0.0017 18.5 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF904) GvpK PF05121.7 KEY72451.1 - 0.036 13.8 3.0 0.037 13.8 0.2 1.9 2 0 0 2 2 2 0 Gas vesicle protein K Phasin PF05597.6 KEY72451.1 - 0.071 12.8 0.7 0.33 10.7 0.1 2.0 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3431 PF11913.3 KEY72453.1 - 7e-82 274.2 0.3 6.8e-65 218.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3431) Bestrophin PF01062.16 KEY72454.1 - 2.8e-48 164.3 1.7 2.9e-30 105.2 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel VIT1 PF01988.14 KEY72454.1 - 0.024 14.1 1.9 0.15 11.5 0.0 2.3 2 0 0 2 2 2 0 VIT family TarH PF02203.10 KEY72454.1 - 0.14 12.0 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue MFS_1 PF07690.11 KEY72455.1 - 4.7e-29 101.2 36.3 4.7e-29 101.2 25.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY72455.1 - 2.6e-10 39.5 20.8 2.3e-08 33.0 14.4 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.3 KEY72455.1 - 4.8e-07 28.6 6.6 4.8e-07 28.6 4.6 2.4 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like TRI12 PF06609.8 KEY72455.1 - 0.00033 18.9 1.0 0.00055 18.2 0.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ABC2_membrane_5 PF13346.1 KEY72455.1 - 1.9 7.7 9.0 0.36 10.0 2.6 2.3 2 0 0 2 2 2 0 ABC-2 family transporter protein Abhydrolase_6 PF12697.2 KEY72456.1 - 5e-17 62.5 0.1 7.1e-17 62.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY72456.1 - 1.1e-09 38.2 0.0 2.1e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY72456.1 - 0.012 15.2 0.1 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lactamase_B_3 PF13483.1 KEY72457.1 - 7.3e-05 22.5 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 KEY72457.1 - 0.018 14.5 0.4 0.035 13.6 0.3 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Pyr_redox_2 PF07992.9 KEY72458.1 - 2e-13 50.6 0.0 7.2e-13 48.8 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY72458.1 - 7.8e-05 22.6 0.0 0.00035 20.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEY72458.1 - 0.00011 21.2 0.3 0.0013 17.6 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 KEY72458.1 - 0.00015 20.9 1.1 0.00019 20.6 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KEY72458.1 - 0.00038 19.4 0.2 0.00069 18.6 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KEY72458.1 - 0.0018 16.8 0.1 0.0029 16.1 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 KEY72458.1 - 0.0024 16.8 0.3 0.0038 16.2 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KEY72458.1 - 0.025 13.7 0.5 0.054 12.5 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.1 KEY72458.1 - 0.029 14.4 0.3 0.1 12.6 0.1 1.9 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEY72458.1 - 0.051 13.3 3.0 0.075 12.8 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.17 KEY72458.1 - 0.12 11.2 0.1 0.23 10.3 0.0 1.6 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.1 KEY72458.1 - 0.2 10.5 0.2 0.58 9.0 0.1 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Zn_clus PF00172.13 KEY72460.1 - 7e-09 35.4 10.9 1.3e-08 34.5 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY72460.1 - 7e-07 28.3 0.3 1.2e-06 27.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Clusterin PF01093.12 KEY72460.1 - 0.75 8.5 3.4 1.2 7.8 2.3 1.2 1 0 0 1 1 1 0 Clusterin NmrA PF05368.8 KEY72461.1 - 1.7e-19 69.9 0.0 2.1e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.15 KEY72461.1 - 0.15 12.1 0.0 19 5.3 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Asp PF00026.18 KEY72462.1 - 3e-63 213.9 0.9 3.5e-63 213.7 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEY72462.1 - 2.4e-05 24.3 0.0 0.0003 20.7 0.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KEY72462.1 - 0.0078 15.7 0.1 0.062 12.8 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal RIO1 PF01163.17 KEY72463.1 - 8.6e-67 224.1 0.7 1.4e-66 223.4 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 KEY72463.1 - 0.00088 18.3 0.1 0.011 14.8 0.1 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEY72463.1 - 0.00089 19.0 0.1 0.1 12.3 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Fungal_trans PF04082.13 KEY72464.1 - 3.8e-21 75.1 1.1 6.7e-21 74.3 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY72464.1 - 5.5e-08 32.5 12.6 1.1e-07 31.6 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RdRP PF05183.7 KEY72465.1 - 7.3e-109 365.0 0.1 1e-108 364.5 0.1 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase peroxidase PF00141.18 KEY72466.1 - 4.9e-29 101.4 0.0 7.3e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Cyclin PF08613.6 KEY72468.1 - 1.9e-37 128.9 0.0 2.9e-37 128.3 0.0 1.4 1 1 0 1 1 1 1 Cyclin TPP_enzyme_N PF02776.13 KEY72469.1 - 2e-42 144.5 0.3 1.3e-40 138.7 0.1 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KEY72469.1 - 3.3e-23 81.9 0.0 1.2e-22 80.1 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KEY72469.1 - 2.9e-18 65.8 1.4 1.9e-17 63.2 0.2 2.7 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain FAD_binding_4 PF01565.18 KEY72470.1 - 6.4e-16 58.0 0.0 1.3e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY72470.1 - 0.033 14.0 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like Catalase PF00199.14 KEY72471.1 - 7.1e-164 545.0 0.9 9.1e-164 544.6 0.6 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KEY72471.1 - 3.7e-20 71.5 0.1 7.7e-20 70.5 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 KEY72471.1 - 5.9e-11 42.0 0.0 1.2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family XFP_N PF09364.5 KEY72472.1 - 1.7e-148 494.2 0.0 3e-148 493.4 0.0 1.3 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 KEY72472.1 - 2.3e-71 239.4 0.0 3.3e-71 238.9 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 KEY72472.1 - 1.2e-70 236.6 0.1 2e-70 235.9 0.1 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.16 KEY72472.1 - 0.0074 15.8 0.0 0.024 14.2 0.0 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.16 KEY72472.1 - 0.081 11.7 0.2 0.17 10.6 0.0 1.6 2 0 0 2 2 2 0 Transketolase, thiamine diphosphate binding domain UDPG_MGDP_dh_N PF03721.9 KEY72473.1 - 2e-20 72.9 0.1 4.2e-18 65.3 0.1 2.2 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 KEY72473.1 - 7.8e-19 67.6 0.0 1.4e-17 63.6 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.10 KEY72473.1 - 5e-05 23.1 0.0 8.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.10 KEY72473.1 - 0.0058 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain TrkA_N PF02254.13 KEY72473.1 - 0.044 13.7 0.0 0.094 12.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 KEY72473.1 - 0.13 11.2 0.2 1 8.2 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase Polysacc_deac_1 PF01522.16 KEY72474.1 - 6e-26 90.4 0.0 1e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 KEY72474.1 - 8.7e-09 35.2 59.1 3.3e-05 23.7 11.8 3.7 3 1 0 3 3 3 2 Chitin recognition protein Chitin_synth_2 PF03142.10 KEY72475.1 - 1e-39 136.3 3.6 8.8e-30 103.5 0.5 2.3 2 1 0 2 2 2 2 Chitin synthase Glycos_transf_2 PF00535.21 KEY72475.1 - 8.7e-11 41.7 0.0 0.00011 21.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 KEY72475.1 - 1.6e-07 31.2 4.8 1.6e-07 31.2 3.3 3.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KEY72475.1 - 3.8e-07 30.1 0.3 0.012 15.4 0.0 3.2 3 0 0 3 3 3 3 Glycosyltransferase like family 2 Glyco_transf_6 PF03414.8 KEY72475.1 - 0.0011 17.5 0.3 0.0021 16.6 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 6 Herpes_gE PF02480.11 KEY72476.1 - 0.0059 14.9 0.0 0.0076 14.5 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.10 KEY72476.1 - 0.44 10.1 3.1 0.91 9.1 2.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Peptidase_M28 PF04389.12 KEY72477.1 - 8.5e-37 126.6 0.0 1.3e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KEY72477.1 - 7.4e-12 44.8 0.0 2.4e-11 43.2 0.0 1.9 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 KEY72477.1 - 0.00051 19.6 0.0 0.0007 19.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PALP PF00291.20 KEY72478.1 - 2.4e-59 201.0 0.0 3.3e-59 200.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 KEY72478.1 - 7.6e-11 41.6 0.0 2.4e-09 36.8 0.0 2.6 2 0 0 2 2 2 1 CBS domain SRPRB PF09439.5 KEY72479.1 - 1.6e-30 105.6 0.0 3.7e-30 104.4 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 KEY72479.1 - 9.6e-10 37.9 0.0 3.1e-08 33.0 0.0 2.4 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KEY72479.1 - 2.7e-07 30.5 0.1 4.4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEY72479.1 - 3.5e-05 23.3 0.1 0.00024 20.5 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KEY72479.1 - 0.0035 17.8 0.0 0.012 16.0 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein Septin PF00735.13 KEY72479.1 - 0.0059 15.6 0.0 0.012 14.6 0.0 1.4 2 0 0 2 2 2 1 Septin Ras PF00071.17 KEY72479.1 - 0.0067 15.8 0.0 0.017 14.4 0.0 1.7 1 1 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KEY72479.1 - 0.0073 15.4 0.0 0.014 14.5 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 KEY72479.1 - 0.027 14.4 0.1 0.066 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain KAP_NTPase PF07693.9 KEY72479.1 - 0.056 12.4 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Dynamin_N PF00350.18 KEY72479.1 - 0.059 13.1 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Dynamin family Arch_ATPase PF01637.13 KEY72479.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase Ank_2 PF12796.2 KEY72480.1 - 4.3e-53 177.6 0.0 9.5e-18 64.3 0.0 3.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 KEY72480.1 - 6.5e-37 123.5 0.3 3e-09 36.2 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat zf-DHHC PF01529.15 KEY72480.1 - 6.3e-34 116.8 8.3 1.2e-33 115.9 5.7 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank_5 PF13857.1 KEY72480.1 - 8.2e-28 95.8 1.3 1.3e-07 31.6 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEY72480.1 - 8.7e-27 93.0 1.4 2.8e-08 34.0 0.1 4.8 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY72480.1 - 2.1e-25 86.2 0.6 2.9e-08 33.1 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Pyr_redox_3 PF13738.1 KEY72482.1 - 1.6e-21 77.2 0.0 1.4e-20 74.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEY72482.1 - 4.8e-13 48.1 0.0 6.3e-12 44.4 0.0 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KEY72482.1 - 1e-12 48.3 0.0 1.2e-09 38.3 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEY72482.1 - 3.4e-10 39.3 0.0 4.2e-07 29.2 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KEY72482.1 - 3.6e-07 30.4 1.8 0.021 15.2 0.5 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY72482.1 - 6.1e-07 29.3 0.2 6.1e-07 29.3 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEY72482.1 - 7.8e-06 25.0 0.0 7.8e-06 25.0 0.0 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KEY72482.1 - 0.00025 20.7 0.4 0.00043 19.9 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KEY72482.1 - 0.00058 19.9 0.1 0.75 9.8 0.0 3.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 KEY72482.1 - 0.00061 19.5 2.4 0.026 14.2 0.1 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KEY72482.1 - 0.00073 18.4 1.7 0.0013 17.6 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KEY72482.1 - 0.014 14.3 1.0 0.014 14.3 0.7 1.9 3 0 0 3 3 3 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KEY72482.1 - 0.054 13.0 0.7 4.2 6.9 0.1 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KEY72482.1 - 0.056 12.5 0.1 0.16 11.0 0.1 1.7 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.9 KEY72482.1 - 0.09 12.1 0.3 0.56 9.5 0.2 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.7 KEY72482.1 - 0.091 11.6 0.0 0.4 9.5 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 KEY72482.1 - 0.13 10.7 4.9 0.033 12.6 0.3 2.0 2 0 0 2 2 2 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 KEY72482.1 - 0.15 11.1 0.1 13 4.8 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KEY72482.1 - 0.17 10.9 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 KEY72482.1 - 0.39 10.4 3.1 0.24 11.0 0.5 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HAUS-augmin3 PF14932.1 KEY72483.1 - 5.6e-05 22.4 8.6 5.6e-05 22.4 6.0 2.7 3 0 0 3 3 3 1 HAUS augmin-like complex subunit 3 DDE_Tnp_IS1595 PF12762.2 KEY72483.1 - 0.035 13.9 0.1 0.078 12.8 0.1 1.5 1 0 0 1 1 1 0 ISXO2-like transposase domain MHC_II_beta PF00969.14 KEY72483.1 - 0.052 13.5 0.2 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain Mnd1 PF03962.10 KEY72483.1 - 0.3 10.7 13.7 0.024 14.3 4.9 2.4 2 1 1 3 3 3 0 Mnd1 family BLOC1_2 PF10046.4 KEY72483.1 - 1.3 9.1 8.9 0.096 12.8 0.7 3.1 3 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Bacillus_HBL PF05791.6 KEY72483.1 - 1.5 8.1 7.4 0.41 9.9 1.6 2.5 2 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF1682 PF07946.9 KEY72483.1 - 2.2 7.0 8.5 3.8 6.2 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF342 PF03961.8 KEY72483.1 - 2.6 6.3 5.0 0.94 7.8 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF2203 PF09969.4 KEY72483.1 - 9.6 6.4 11.1 0.58 10.3 2.1 2.9 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) LrgB PF04172.11 KEY72484.1 - 5.5e-14 51.8 8.1 3.6e-08 32.8 0.2 2.5 2 0 0 2 2 2 2 LrgB-like family DUF4153 PF13687.1 KEY72484.1 - 0.0016 18.0 6.6 0.011 15.2 0.3 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4153) Rotamase PF00639.16 KEY72485.1 - 1.6e-23 83.2 0.0 2.2e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 KEY72485.1 - 5.9e-17 62.0 0.0 7.3e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 KEY72485.1 - 7.4e-08 32.1 0.3 7.4e-08 32.1 0.2 1.7 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 KEY72485.1 - 5.1e-06 27.1 0.0 6.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain RNA_POL_M_15KD PF02150.11 KEY72486.1 - 1.3e-10 40.7 3.3 1.3e-10 40.7 2.3 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 KEY72486.1 - 3.7e-08 32.8 8.4 7.2e-08 31.9 0.1 3.6 3 0 0 3 3 3 2 Transcription factor S-II (TFIIS) Ribosomal_L14 PF00238.14 KEY72487.1 - 6.3e-44 148.6 1.7 7e-44 148.5 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e FlgH PF02107.11 KEY72487.1 - 0.01 15.3 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein SET PF00856.23 KEY72488.1 - 8.9e-10 39.0 0.0 5.6e-09 36.5 0.0 2.5 2 0 0 2 2 2 1 SET domain Peptidase_M28 PF04389.12 KEY72489.1 - 1.6e-32 112.6 0.0 2.7e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KEY72489.1 - 5.5e-13 48.4 0.1 3.2e-12 46.0 0.2 2.3 2 1 0 2 2 2 1 PA domain Nicastrin PF05450.10 KEY72489.1 - 0.0029 16.8 0.4 0.065 12.4 0.0 2.2 2 0 0 2 2 2 1 Nicastrin Peptidase_M20 PF01546.23 KEY72489.1 - 0.0059 16.1 0.1 0.026 14.0 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 BTB PF00651.26 KEY72491.1 - 5.5e-06 26.3 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Glyoxalase_3 PF13468.1 KEY72492.1 - 9.5e-23 80.9 0.1 1.4e-22 80.4 0.1 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain DUF1973 PF09315.6 KEY72492.1 - 0.065 12.6 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1973) DUF4110 PF13422.1 KEY72492.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) DUF1993 PF09351.5 KEY72493.1 - 2.8e-44 150.8 0.0 3.1e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Ldh_2 PF02615.9 KEY72494.1 - 1.5e-93 313.1 0.0 2.1e-93 312.7 0.0 1.2 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase NicO PF03824.11 KEY72494.1 - 5.7e-63 212.8 8.3 5.7e-63 212.8 5.8 2.1 3 0 0 3 3 3 1 High-affinity nickel-transport protein 4HBT PF03061.17 KEY72494.1 - 4.9e-13 48.9 0.7 1.4e-12 47.5 0.5 1.8 1 0 0 1 1 1 1 Thioesterase superfamily Peptidase_C2 PF00648.16 KEY72496.1 - 1.4e-52 178.5 1.4 5.8e-36 124.0 0.4 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease APG17 PF04108.7 KEY72498.1 - 3.6e-95 319.2 1.1 4.3e-95 318.9 0.8 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 YgaB PF14182.1 KEY72498.1 - 0.022 14.9 1.4 0.19 11.9 0.2 2.5 2 0 0 2 2 2 0 YgaB-like protein Bacillus_HBL PF05791.6 KEY72498.1 - 0.027 13.8 0.4 9.2 5.5 0.0 2.8 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Choline_transpo PF04515.7 KEY72499.1 - 1.5e-96 323.0 16.3 1.5e-96 323.0 11.3 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.8 KEY72499.1 - 2.2 8.3 4.1 2 8.4 1.0 2.3 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3789 PF12664.2 KEY72499.1 - 5.3 6.4 7.3 16 4.9 5.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) AMP-binding PF00501.23 KEY72500.1 - 1e-79 267.9 0.0 2.1e-79 266.8 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KEY72500.1 - 9.7e-64 214.6 0.0 7.6e-63 211.7 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 KEY72500.1 - 6.8e-33 113.9 4.9 2.8e-30 105.4 2.7 2.7 2 0 0 2 2 2 2 short chain dehydrogenase Epimerase PF01370.16 KEY72500.1 - 9.9e-21 74.2 1.1 8.8e-13 48.2 0.0 3.2 4 0 0 4 4 4 2 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KEY72500.1 - 7.8e-19 68.3 0.4 1.5e-18 67.5 0.3 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY72500.1 - 1.5e-17 63.8 3.5 2.4e-14 53.3 2.1 2.5 2 0 0 2 2 2 2 KR domain PP-binding PF00550.20 KEY72500.1 - 7.8e-10 38.8 0.0 1.7e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 KEY72500.1 - 4e-08 33.4 3.1 1.4e-05 25.1 1.4 3.4 3 0 0 3 3 3 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEY72500.1 - 2.3e-07 29.7 0.1 0.0024 16.6 0.0 3.0 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KEY72500.1 - 4.3e-07 29.0 0.7 0.00023 20.1 0.1 3.5 3 1 0 3 3 3 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KEY72500.1 - 1.8e-05 23.8 1.1 0.029 13.2 0.1 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein AMP-binding_C PF13193.1 KEY72500.1 - 0.00012 22.9 3.4 0.00021 22.1 0.0 3.2 4 0 0 4 4 3 1 AMP-binding enzyme C-terminal domain Eno-Rase_NADH_b PF12242.3 KEY72500.1 - 0.033 13.9 1.2 0.089 12.5 0.8 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 KEY72500.1 - 0.062 12.5 1.3 4.6 6.4 1.0 2.7 3 0 0 3 3 3 0 NmrA-like family Chitin_bind_3 PF03067.10 KEY72501.1 - 3.4e-13 50.2 0.2 9.3e-13 48.8 0.1 1.8 1 1 0 1 1 1 1 Chitin binding domain Arylsulfotran_2 PF14269.1 KEY72502.1 - 1.8e-54 184.9 1.3 2.3e-54 184.5 0.9 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KEY72502.1 - 2.9e-17 62.3 0.1 5e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) OPT PF03169.10 KEY72503.1 - 1.9e-160 535.3 52.8 2.1e-160 535.1 36.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ABC_tran PF00005.22 KEY72505.1 - 1.2e-43 148.6 0.0 4.2e-28 98.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEY72505.1 - 4.1e-23 82.1 21.9 3.2e-16 59.5 3.5 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KEY72505.1 - 4.1e-15 55.6 0.0 3.6e-06 26.3 0.0 3.9 1 1 2 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KEY72505.1 - 1.9e-06 27.9 4.3 0.0013 18.7 0.1 3.7 4 0 0 4 4 3 2 AAA ATPase domain AAA_29 PF13555.1 KEY72505.1 - 7.6e-06 25.3 0.2 0.068 12.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 KEY72505.1 - 1.3e-05 25.3 0.5 0.34 10.8 0.0 4.1 2 2 1 3 3 3 1 AAA domain T2SE PF00437.15 KEY72505.1 - 0.00011 21.1 0.0 0.34 9.7 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF258 PF03193.11 KEY72505.1 - 0.00012 21.3 0.1 0.14 11.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KEY72505.1 - 0.00013 22.3 0.0 0.032 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KEY72505.1 - 0.00013 21.5 0.2 0.055 12.9 0.1 2.7 2 1 0 2 2 2 1 AAA-like domain DUF87 PF01935.12 KEY72505.1 - 0.00028 20.7 0.6 0.00067 19.5 0.0 1.9 2 0 0 2 2 1 1 Domain of unknown function DUF87 Dynamin_N PF00350.18 KEY72505.1 - 0.0004 20.2 0.1 0.15 11.8 0.0 2.5 2 0 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.13 KEY72505.1 - 0.0014 18.1 0.0 0.021 14.3 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_19 PF13245.1 KEY72505.1 - 0.0016 18.1 0.2 2.2 8.0 0.0 3.1 2 0 0 2 2 2 1 Part of AAA domain MMR_HSR1 PF01926.18 KEY72505.1 - 0.0016 18.3 0.0 0.11 12.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 KEY72505.1 - 0.0016 17.5 0.6 0.46 9.5 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin AAA_22 PF13401.1 KEY72505.1 - 0.002 18.2 0.8 1.2 9.2 0.2 3.5 3 1 0 3 3 2 1 AAA domain AAA_33 PF13671.1 KEY72505.1 - 0.0028 17.5 0.1 0.91 9.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 KEY72505.1 - 0.0046 16.4 0.3 1.3 8.4 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KEY72505.1 - 0.0091 16.8 0.0 0.15 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KEY72505.1 - 0.024 14.5 0.0 1.9 8.4 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KEY72505.1 - 0.032 14.5 0.2 1.5 9.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 KEY72505.1 - 0.039 13.3 0.0 1.9 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KEY72505.1 - 0.12 12.8 0.0 9.9 6.6 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein DEAD PF00270.24 KEY72505.1 - 0.14 11.6 0.0 3.9 6.9 0.0 2.8 2 1 0 2 2 2 0 DEAD/DEAH box helicase AIG1 PF04548.11 KEY72505.1 - 0.95 8.5 3.9 3.2 6.8 0.0 3.1 4 0 0 4 4 4 0 AIG1 family AA_permease PF00324.16 KEY72506.1 - 3.3e-113 378.5 41.5 4e-113 378.3 28.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEY72506.1 - 1.2e-19 70.1 45.8 1.6e-19 69.7 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 KEY72506.1 - 0.011 15.4 2.2 0.011 15.4 1.5 4.0 2 1 2 4 4 4 0 Domain of unknown function (DUF1772) HET PF06985.6 KEY72507.1 - 8.9e-25 87.4 0.1 1.6e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PSII_Ycf12 PF05969.6 KEY72508.1 - 0.042 13.4 2.5 0.043 13.4 0.2 2.2 2 0 0 2 2 2 0 Photosystem II complex subunit Ycf12 MS_channel PF00924.13 KEY72508.1 - 0.77 9.0 2.6 1.8 7.8 1.8 1.6 1 0 0 1 1 1 0 Mechanosensitive ion channel Ank_2 PF12796.2 KEY72510.1 - 1.9e-29 101.8 2.1 3.4e-19 68.9 0.2 2.9 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEY72510.1 - 9.1e-25 86.5 1.0 3.7e-10 40.0 0.0 3.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 KEY72510.1 - 2.1e-19 68.2 2.2 1.4e-06 27.8 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 KEY72510.1 - 3e-17 60.9 0.6 0.00014 21.7 0.0 4.4 4 1 1 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KEY72510.1 - 8.7e-16 57.5 0.8 8.8e-08 32.1 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) IBR PF01485.16 KEY72511.1 - 7.4e-10 38.5 30.7 5.2e-06 26.2 0.1 5.0 4 2 0 4 4 3 3 IBR domain Sgf11 PF08209.6 KEY72511.1 - 0.0031 16.8 6.8 0.0044 16.3 0.2 3.4 3 0 0 3 3 3 1 Sgf11 (transcriptional regulation protein) Zn-ribbon_8 PF09723.5 KEY72511.1 - 0.009 15.9 14.8 13 5.8 0.1 5.4 5 0 0 5 5 5 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 KEY72511.1 - 0.2 11.1 12.4 0.24 10.9 0.3 3.9 4 0 0 4 4 4 0 zinc-ribbon domain Prim_Zn_Ribbon PF08273.7 KEY72511.1 - 0.8 9.8 9.2 2.8 8.1 0.4 4.0 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase zf-C2HC_2 PF13913.1 KEY72511.1 - 0.81 9.4 6.3 0.23 11.1 0.4 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PhnA_Zn_Ribbon PF08274.7 KEY72511.1 - 0.91 9.3 8.0 1.4 8.7 0.0 3.8 3 0 0 3 3 3 0 PhnA Zinc-Ribbon UPF0547 PF10571.4 KEY72511.1 - 1.3 8.7 8.1 12 5.6 0.1 3.6 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.1 KEY72511.1 - 1.4 8.2 16.9 0.11 11.7 0.7 3.6 4 0 0 4 4 4 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 KEY72511.1 - 2.5 7.6 10.2 3.5 7.1 0.4 4.0 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit YhfH PF14149.1 KEY72511.1 - 4.6 7.1 14.7 1.8 8.4 3.6 3.5 3 0 0 3 3 3 0 YhfH-like protein zf-ISL3 PF14690.1 KEY72511.1 - 5.1 7.2 11.0 20 5.2 0.0 3.5 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DZR PF12773.2 KEY72511.1 - 8.1 6.3 21.0 5.1 6.9 0.8 4.3 3 1 0 3 3 3 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 KEY72512.1 - 0.088 12.7 0.1 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Zinc ribbon domain HET PF06985.6 KEY72515.1 - 1.2e-28 100.0 0.4 2.2e-28 99.1 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 KEY72516.1 - 3.4e-20 72.0 57.4 1.7e-13 50.0 19.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY72517.1 - 8.5e-129 430.0 26.8 9.8e-129 429.8 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY72517.1 - 7.2e-23 80.8 38.8 7.3e-15 54.5 12.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_transf_20 PF00982.16 KEY72518.1 - 1.2e-150 502.0 0.0 1.6e-150 501.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KEY72518.1 - 7.7e-72 240.9 0.0 1.5e-71 240.0 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase PRT_C PF08372.5 KEY72518.1 - 0.14 11.6 0.2 5.6 6.4 0.2 2.5 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Zn_clus PF00172.13 KEY72519.1 - 4.8e-09 35.9 8.7 8.7e-09 35.1 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY72519.1 - 2.5e-06 26.5 0.2 7e-06 25.0 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.8 KEY72521.1 - 6.7e-09 35.3 0.0 8.4e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family WD40 PF00400.27 KEY72523.1 - 1.2e-58 193.0 16.3 5.2e-11 41.9 0.0 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KEY72523.1 - 6.5e-08 32.5 0.0 0.00028 20.6 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KEY72523.1 - 1.4e-07 30.1 2.5 0.0085 14.2 0.5 3.5 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KEY72523.1 - 3.7e-05 22.6 0.0 0.21 10.2 0.0 3.5 2 2 1 3 3 3 2 Nup133 N terminal like DUF566 PF04484.7 KEY72523.1 - 3.9 6.8 21.5 5.7 6.3 14.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) GPI-anchored PF10342.4 KEY72524.1 - 3.2e-19 69.1 0.1 3.2e-19 69.1 0.1 2.6 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 KEY72524.1 - 0.0013 18.2 3.1 0.071 12.5 2.1 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) THF_DHG_CYH PF00763.18 KEY72525.1 - 7.2e-19 67.9 0.1 1e-18 67.4 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 KEY72525.1 - 3.4e-14 52.2 0.1 9.6e-09 34.5 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_5 PF00496.17 KEY72525.1 - 0.058 12.2 0.1 0.08 11.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Apq12 PF12716.2 KEY72527.1 - 4.3e-07 29.5 17.0 7.5e-07 28.7 11.8 1.4 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis ATP-synt_C PF00137.16 KEY72527.1 - 0.14 12.0 0.8 0.39 10.6 0.6 1.7 1 0 0 1 1 1 0 ATP synthase subunit C ATP_bind_1 PF03029.12 KEY72528.1 - 1.3e-70 237.6 0.0 2.3e-70 236.8 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KEY72528.1 - 7.2e-05 23.6 2.2 0.00027 21.7 0.0 2.6 2 2 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KEY72528.1 - 0.0018 18.1 0.1 0.023 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KEY72528.1 - 0.0037 17.1 0.0 0.0075 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEY72528.1 - 0.0044 17.1 0.2 0.035 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEY72528.1 - 0.0058 16.1 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_31 PF13614.1 KEY72528.1 - 0.015 15.2 0.0 0.049 13.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEY72528.1 - 0.015 15.4 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 KEY72528.1 - 0.017 14.5 0.0 0.051 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain MobB PF03205.9 KEY72528.1 - 0.033 13.8 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KEY72528.1 - 0.054 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.22 KEY72528.1 - 0.11 11.9 0.3 18 4.7 0.0 2.7 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_19 PF13245.1 KEY72528.1 - 0.13 12.0 0.0 0.38 10.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 KEY72528.1 - 0.15 12.3 0.9 1.8 8.8 0.0 2.9 3 1 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 KEY72528.1 - 0.17 11.8 0.0 0.4 10.6 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase S-AdoMet_synt_C PF02773.11 KEY72529.1 - 8.5e-76 252.2 0.1 1.5e-75 251.5 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KEY72529.1 - 6.8e-48 161.5 0.0 1.1e-47 160.8 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KEY72529.1 - 6.7e-42 141.7 0.5 2.6e-41 139.8 0.0 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain DUF2312 PF10073.4 KEY72529.1 - 0.034 13.4 0.0 0.074 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) PI-PLC-X PF00388.14 KEY72531.1 - 3.1e-14 52.6 0.0 4.9e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain MaoC_dehydratas PF01575.14 KEY72534.1 - 8.6e-22 76.8 0.0 1.4e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KEY72534.1 - 4.4e-07 29.7 0.0 9.1e-06 25.4 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase ERp29_N PF07912.8 KEY72534.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 ERp29, N-terminal domain LRR_4 PF12799.2 KEY72535.1 - 1.3e-20 72.5 0.8 5.9e-06 25.7 0.5 5.9 4 2 2 7 7 7 4 Leucine Rich repeats (2 copies) CAP_GLY PF01302.20 KEY72535.1 - 1.3e-19 69.6 0.0 2e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.1 KEY72535.1 - 2.5e-11 43.1 6.4 0.00051 19.7 0.9 5.5 3 2 3 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 KEY72535.1 - 1.2e-08 33.7 7.0 3.2 8.1 0.0 7.3 6 1 1 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 KEY72535.1 - 1e-07 30.9 3.3 21 5.9 0.0 7.0 6 0 0 6 6 6 1 Leucine rich repeat LRR_6 PF13516.1 KEY72535.1 - 3.7e-07 29.5 5.2 3 8.2 0.0 7.1 8 0 0 8 8 8 1 Leucine Rich repeat LRR_9 PF14580.1 KEY72535.1 - 0.001 18.6 0.4 1.9 8.0 0.0 3.5 2 2 1 4 4 4 1 Leucine-rich repeat Aldo_ket_red PF00248.16 KEY72536.1 - 5.4e-50 169.8 0.0 6e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AdoHcyase PF05221.12 KEY72536.1 - 0.061 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase WD40 PF00400.27 KEY72537.1 - 7.4e-18 63.6 12.0 1.4e-08 34.2 0.1 6.4 8 0 0 8 8 8 5 WD domain, G-beta repeat ATP-synt_E PF05680.7 KEY72538.1 - 5e-24 84.0 0.1 5.1e-24 84.0 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain ABC_trans_N PF14510.1 KEY72538.1 - 0.00035 20.5 0.2 0.00044 20.2 0.1 1.3 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF3186 PF11382.3 KEY72538.1 - 0.038 13.1 0.0 0.046 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) STT3 PF02516.9 KEY72539.1 - 3.5e-129 431.8 37.0 5.8e-124 414.7 24.4 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Dpy19 PF10034.4 KEY72539.1 - 0.0065 14.7 0.1 0.0065 14.7 0.1 1.6 2 0 0 2 2 2 1 Q-cell neuroblast polarisation Pkinase PF00069.20 KEY72541.1 - 5.9e-63 212.4 0.0 1.1e-62 211.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY72541.1 - 2.3e-29 102.2 0.0 4e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KEY72541.1 - 1.4e-09 37.9 0.0 3.6e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KEY72541.1 - 0.035 13.0 0.0 0.18 10.7 0.0 2.1 2 1 0 2 2 2 0 Kinase-like Spo0A_C PF08769.6 KEY72541.1 - 1.1 9.1 2.8 2.2 8.1 0.8 2.1 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal PH PF00169.24 KEY72542.1 - 9.5e-06 25.7 0.0 0.00018 21.6 0.0 2.5 2 1 0 2 2 2 1 PH domain PH_9 PF15410.1 KEY72542.1 - 0.0024 18.0 0.0 0.0048 17.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Peptidase_S9_N PF02897.10 KEY72542.1 - 0.012 14.2 0.1 0.019 13.5 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain PP2C_2 PF13672.1 KEY72543.1 - 1.7e-05 24.3 0.2 2.5e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KEY72543.1 - 0.0034 17.1 0.0 0.01 15.5 0.0 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Fcf1 PF04900.7 KEY72544.1 - 2.3e-25 88.6 0.1 4.6e-25 87.6 0.1 1.5 1 0 0 1 1 1 1 Fcf1 DUF4407 PF14362.1 KEY72544.1 - 0.15 10.9 3.4 0.22 10.4 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.9 KEY72544.1 - 0.21 9.5 4.3 0.29 9.1 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1087 PF06465.8 KEY72544.1 - 0.78 9.7 7.4 0.12 12.3 1.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) DUF726 PF05277.7 KEY72545.1 - 9.2e-127 422.6 1.7 1.3e-126 422.2 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) VSP PF03302.8 KEY72547.1 - 1.8e-05 23.5 0.0 2.5e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein Mid2 PF04478.7 KEY72547.1 - 4.3e-05 22.9 0.0 9.6e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Rifin_STEVOR PF02009.11 KEY72547.1 - 0.0017 18.0 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family TMEM154 PF15102.1 KEY72547.1 - 0.0017 18.0 0.0 0.0035 17.0 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Podoplanin PF05808.6 KEY72547.1 - 0.0043 16.6 0.4 0.011 15.3 0.3 1.7 1 0 0 1 1 1 1 Podoplanin DUF912 PF06024.7 KEY72547.1 - 0.0057 16.6 0.0 0.02 14.9 0.0 1.9 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Herpes_gE PF02480.11 KEY72547.1 - 0.017 13.4 0.0 0.03 12.5 0.0 1.5 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4448 PF14610.1 KEY72547.1 - 0.028 13.9 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Rax2 PF12768.2 KEY72547.1 - 0.042 13.0 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Shisa PF13908.1 KEY72547.1 - 0.045 13.9 0.0 0.045 13.9 0.0 2.4 2 1 1 3 3 2 0 Wnt and FGF inhibitory regulator DUF1183 PF06682.7 KEY72547.1 - 0.058 12.9 2.9 21 4.5 3.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) DUF4199 PF13858.1 KEY72547.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) YajC PF02699.10 KEY72547.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit YebO PF13974.1 KEY72547.1 - 0.15 11.8 1.0 0.4 10.4 0.7 1.7 1 0 0 1 1 1 0 YebO-like protein CcmH PF03918.9 KEY72547.1 - 0.18 10.7 0.0 8.1 5.4 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C biogenesis protein SSP160 PF06933.6 KEY72547.1 - 0.94 7.3 10.2 1.3 6.9 7.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF846 PF05832.7 KEY72548.1 - 9.7e-52 174.4 10.7 1.2e-51 174.2 7.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF4191 PF13829.1 KEY72548.1 - 0.23 10.5 12.9 0.34 9.9 2.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) Tic20 PF09685.5 KEY72548.1 - 0.31 11.0 12.7 0.28 11.1 1.3 2.2 2 0 0 2 2 2 0 Tic20-like protein Wzy_C PF04932.10 KEY72548.1 - 0.59 9.8 10.7 0.042 13.6 1.5 2.0 2 0 0 2 2 2 0 O-Antigen ligase RseC_MucC PF04246.7 KEY72548.1 - 4.6 6.8 8.8 1.6 8.3 0.3 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF2530 PF10745.4 KEY72548.1 - 8.7 6.4 7.7 3 7.8 2.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) HpcH_HpaI PF03328.9 KEY72549.1 - 1.5e-42 144.9 0.1 8.5e-42 142.5 0.0 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 KEY72549.1 - 4.6e-12 45.4 0.1 4.8e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold CDC45 PF02724.9 KEY72550.1 - 0.026 12.5 1.4 0.034 12.2 1.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RRM_1 PF00076.17 KEY72551.1 - 1.7e-22 78.8 0.0 2.2e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY72551.1 - 1e-14 54.2 0.0 1.4e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY72551.1 - 2.7e-08 33.5 0.0 3.6e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ChaC PF04752.7 KEY72552.1 - 3e-52 177.1 0.0 3.7e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein EF-hand_1 PF00036.27 KEY72553.1 - 8.8e-27 90.3 3.2 9.7e-07 27.6 0.1 5.4 5 1 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 KEY72553.1 - 1.5e-23 82.6 2.8 2.9e-09 36.9 0.0 3.6 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 KEY72553.1 - 2.6e-22 78.1 4.3 9.2e-09 34.7 0.0 4.3 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KEY72553.1 - 3.8e-21 73.0 3.8 0.00085 19.0 0.2 5.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 KEY72553.1 - 2e-18 64.8 4.6 0.00033 19.8 0.0 4.6 4 0 0 4 4 4 4 EF hand zf-RING_5 PF14634.1 KEY72554.1 - 2.3 7.9 11.3 6.6 6.5 7.8 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Hep_59 PF07052.6 KEY72555.1 - 3.9e-07 30.3 1.3 2.3e-06 27.8 0.0 2.6 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 Acylphosphatase PF00708.13 KEY72556.1 - 8.2e-24 83.5 1.3 9.1e-24 83.3 0.9 1.0 1 0 0 1 1 1 1 Acylphosphatase HA2 PF04408.18 KEY72557.1 - 3.5e-26 91.2 0.2 1.9e-25 88.8 0.0 2.5 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KEY72557.1 - 1.8e-25 88.9 0.0 4.6e-24 84.4 0.0 2.7 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KEY72557.1 - 6.7e-13 48.3 0.0 2e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEY72557.1 - 3.4e-07 29.9 0.0 7.7e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEY72557.1 - 2.9e-05 24.2 0.2 7.7e-05 22.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain T2SE PF00437.15 KEY72557.1 - 0.00018 20.5 0.0 0.00037 19.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 KEY72557.1 - 0.00022 21.1 0.2 0.14 12.0 0.0 3.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KEY72557.1 - 0.001 18.1 0.0 0.0024 16.8 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 KEY72557.1 - 0.0054 15.8 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 KaiC SRP54 PF00448.17 KEY72557.1 - 0.017 14.5 0.0 0.037 13.4 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 KEY72557.1 - 0.021 14.6 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_14 PF13173.1 KEY72557.1 - 0.023 14.6 0.3 0.15 11.9 0.2 2.2 1 1 0 1 1 1 0 AAA domain GAD PF02938.9 KEY72557.1 - 0.03 14.4 0.0 0.077 13.1 0.0 1.6 1 0 0 1 1 1 0 GAD domain ABC_tran PF00005.22 KEY72557.1 - 0.06 13.6 0.3 0.32 11.2 0.0 2.4 2 0 0 2 2 2 0 ABC transporter G-alpha PF00503.15 KEY72557.1 - 0.24 10.0 4.6 0.047 12.3 0.4 1.9 2 0 0 2 2 2 0 G-protein alpha subunit WD40 PF00400.27 KEY72558.1 - 7.5e-25 85.8 9.5 1.8e-07 30.8 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 KEY72558.1 - 0.00092 17.4 3.2 0.0017 16.5 0.7 2.3 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Terpene_synth_C PF03936.11 KEY72560.1 - 3.2e-08 33.1 0.0 5.1e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Polysacc_deac_1 PF01522.16 KEY72561.1 - 5.5e-22 77.7 0.0 9.5e-22 76.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF605 PF04652.11 KEY72562.1 - 0.55 9.5 15.3 0.63 9.3 10.6 1.1 1 0 0 1 1 1 0 Vta1 like DUF1179 PF06678.6 KEY72562.1 - 5.3 7.3 5.9 0.89 9.8 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1179) Cys_Met_Meta_PP PF01053.15 KEY72563.1 - 1.7e-58 197.7 0.0 1.2e-57 195.0 0.0 2.1 2 1 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KEY72563.1 - 0.052 12.2 0.0 0.088 11.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V ig PF00047.20 KEY72564.1 - 0.094 12.8 0.1 0.81 9.8 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain GspL_C PF12693.2 KEY72565.1 - 0.0032 17.2 0.1 0.0058 16.3 0.1 1.4 1 0 0 1 1 1 1 GspL periplasmic domain DUF2681 PF10883.3 KEY72565.1 - 0.082 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) LSM PF01423.17 KEY72566.1 - 2.2e-19 68.7 0.2 2.5e-19 68.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KEY72566.1 - 0.0006 19.6 0.1 0.0008 19.2 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain SPAN PF02510.9 KEY72566.1 - 0.014 14.5 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 Surface presentation of antigens protein LSM14 PF12701.2 KEY72566.1 - 0.033 13.9 0.1 0.04 13.7 0.1 1.1 1 0 0 1 1 1 0 Scd6-like Sm domain Rad60-SLD PF11976.3 KEY72567.1 - 2.6e-16 59.0 0.1 5.6e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KEY72567.1 - 0.0021 17.4 0.0 0.005 16.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Cellulase-like PF12876.2 KEY72567.1 - 0.1 13.0 0.1 0.48 10.9 0.0 2.1 2 0 0 2 2 2 0 Sugar-binding cellulase-like SIR2 PF02146.12 KEY72568.1 - 1.1e-24 87.1 0.0 3.9e-16 59.2 0.0 2.3 2 0 0 2 2 2 2 Sir2 family NUP50 PF08911.6 KEY72568.1 - 0.035 14.4 1.8 0.1 12.9 1.3 1.8 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) GATase_2 PF00310.16 KEY72569.1 - 1e-15 57.3 0.0 8.4e-12 44.4 0.0 2.6 2 1 1 3 3 3 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KEY72569.1 - 2.7e-13 50.0 0.0 5.2e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 KEY72569.1 - 1.8e-11 43.8 0.1 4.9e-11 42.4 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 KEY72569.1 - 1.8e-10 40.6 0.0 2.9e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain ADK PF00406.17 KEY72570.1 - 1.9e-17 63.5 0.0 2.6e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 KEY72570.1 - 2.6e-09 37.4 0.0 2.5e-08 34.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEY72570.1 - 6.6e-08 33.4 0.2 1.4e-06 29.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEY72570.1 - 1.2e-06 28.4 0.0 0.0087 15.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain Thymidylate_kin PF02223.12 KEY72570.1 - 0.0094 15.3 0.0 0.031 13.6 0.0 1.7 2 0 0 2 2 2 1 Thymidylate kinase Zeta_toxin PF06414.7 KEY72570.1 - 0.012 14.6 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.12 KEY72570.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Radical_SAM PF04055.16 KEY72571.1 - 4.1e-17 62.8 0.6 7.5e-17 61.9 0.4 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 KEY72571.1 - 2.8e-07 30.5 0.2 7.8e-07 29.1 0.1 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 KEY72571.1 - 4.3e-07 30.1 0.4 1.2e-06 28.7 0.1 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Tat PF00539.13 KEY72571.1 - 2.2 7.9 7.7 5.8 6.6 1.0 2.7 3 0 0 3 3 3 0 Transactivating regulatory protein (Tat) CYTH PF01928.16 KEY72572.1 - 2.2e-08 34.0 0.2 5e-08 32.8 0.1 1.6 2 0 0 2 2 2 1 CYTH domain Rhomboid PF01694.17 KEY72573.1 - 6.6e-18 65.1 12.6 6.6e-18 65.1 8.7 1.8 1 1 0 2 2 2 1 Rhomboid family Metal_resist PF13801.1 KEY72573.1 - 0.1 12.5 14.3 2.3 8.1 0.2 4.2 2 1 1 3 3 3 0 Heavy-metal resistance Pex14_N PF04695.8 KEY72573.1 - 1.4 8.9 3.9 5.7 6.9 0.3 3.2 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region IU_nuc_hydro PF01156.14 KEY72577.1 - 2.8e-56 191.0 0.0 5.8e-45 153.8 0.0 2.1 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase LSM PF01423.17 KEY72578.1 - 1.4e-15 56.5 0.0 1.9e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KEY72578.1 - 0.13 12.1 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain WD40 PF00400.27 KEY72579.1 - 8.9e-51 168.0 23.8 1.2e-10 40.8 0.8 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 KEY72579.1 - 4.2e-14 51.5 1.9 1.2e-13 50.0 1.3 1.8 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Cyclin_N PF00134.18 KEY72579.1 - 1.6e-10 40.6 0.1 3.4e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain eIF2A PF08662.6 KEY72579.1 - 0.0045 16.7 0.0 1.7 8.3 0.0 3.8 3 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 KEY72579.1 - 0.013 14.6 0.1 0.38 9.7 0.0 2.7 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Pkinase PF00069.20 KEY72580.1 - 1e-65 221.5 0.0 1.2e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY72580.1 - 7.5e-30 103.8 0.0 1.1e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY72580.1 - 0.012 14.5 0.0 0.021 13.8 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Pkinase_C PF00433.19 KEY72580.1 - 0.018 15.5 0.0 0.037 14.5 0.0 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain APH PF01636.18 KEY72580.1 - 0.059 13.0 0.6 1.2 8.8 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family PIF1 PF05970.9 KEY72581.1 - 8.8e-35 120.3 0.0 4e-24 85.2 0.0 2.5 2 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 KEY72581.1 - 9.8e-11 41.5 0.0 4.9e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain Herpes_Helicase PF02689.9 KEY72581.1 - 6e-06 24.3 0.1 2.9e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 KEY72581.1 - 1.1e-05 25.5 0.1 5.6e-05 23.2 0.0 2.1 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 KEY72581.1 - 0.00025 20.7 0.0 0.00054 19.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 KEY72581.1 - 0.00037 20.6 0.0 0.0029 17.7 0.0 2.3 1 1 0 1 1 1 1 RNA helicase AAA_5 PF07728.9 KEY72581.1 - 0.0024 17.6 0.0 0.0066 16.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEY72581.1 - 0.0027 17.8 0.0 0.0086 16.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KEY72581.1 - 0.006 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 KEY72581.1 - 0.0082 15.6 0.1 2.8 7.4 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.13 KEY72581.1 - 0.02 14.3 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.1 KEY72581.1 - 0.037 13.9 0.1 0.29 11.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 KEY72581.1 - 0.048 12.5 0.1 0.098 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 KEY72581.1 - 0.057 13.7 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 KEY72581.1 - 0.068 12.5 0.0 2 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KEY72581.1 - 0.073 13.0 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.10 KEY72581.1 - 0.081 11.5 0.0 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 KEY72581.1 - 0.14 11.6 0.4 0.28 10.5 0.3 1.5 1 0 0 1 1 1 0 AAA-like domain NTPase_1 PF03266.10 KEY72581.1 - 0.14 11.8 0.0 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 NTPase Pox_A32 PF04665.7 KEY72581.1 - 0.16 11.2 0.1 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein TSC22 PF01166.13 KEY72584.1 - 0.0023 17.8 0.5 0.0041 17.0 0.0 1.6 2 0 0 2 2 2 1 TSC-22/dip/bun family Mto2_bdg PF12808.2 KEY72584.1 - 0.05 13.7 1.1 0.064 13.3 0.1 1.6 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_1 PF00170.16 KEY72584.1 - 0.053 13.4 0.2 0.11 12.4 0.1 1.6 2 0 0 2 2 2 0 bZIP transcription factor DUF904 PF06005.7 KEY72584.1 - 0.11 12.8 0.1 0.47 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) PRA1 PF03208.14 KEY72585.1 - 1.1e-21 76.7 0.3 2.3e-21 75.7 0.2 1.5 1 0 0 1 1 1 1 PRA1 family protein SUR7 PF06687.7 KEY72585.1 - 3.7e-08 33.2 0.4 5.3e-07 29.4 0.3 2.2 1 1 0 1 1 1 1 SUR7/PalI family rve PF00665.21 KEY72586.1 - 3.2e-07 30.4 0.1 8e-07 29.1 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Ank_2 PF12796.2 KEY72587.1 - 5.3e-32 110.0 0.0 1.7e-10 41.0 0.0 4.5 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KEY72587.1 - 7.8e-19 66.4 6.1 0.00063 19.4 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 KEY72587.1 - 1.4e-17 63.6 0.1 2.9e-06 27.6 0.0 5.6 8 1 0 8 8 8 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY72587.1 - 4.9e-17 60.3 6.9 0.063 13.5 0.0 8.6 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.1 KEY72587.1 - 8.4e-15 54.4 3.1 0.001 19.2 0.0 7.2 6 2 3 9 9 9 4 Ankyrin repeats (many copies) DUF3447 PF11929.3 KEY72587.1 - 0.067 12.9 0.0 0.33 10.7 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3447) DNA_ligase_A_M PF01068.16 KEY72588.1 - 8.2e-22 77.5 0.0 1.3e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KEY72588.1 - 1.2e-10 41.4 0.1 2.3e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus PNP_UDP_1 PF01048.15 KEY72590.1 - 0.016 14.2 0.5 0.016 14.1 0.4 1.0 1 0 0 1 1 1 0 Phosphorylase superfamily Fungal_trans PF04082.13 KEY72592.1 - 4.5e-14 51.9 0.0 6.3e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY72592.1 - 3.3e-07 30.0 7.7 6.6e-07 29.1 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DDE_Tnp_1_7 PF13843.1 KEY72593.1 - 1.6e-23 83.3 0.0 1.9e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 GATA PF00320.22 KEY72594.1 - 1.4e-14 53.1 5.6 2.7e-14 52.2 3.9 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF2587 PF10759.4 KEY72594.1 - 0.019 14.3 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) GSu_C4xC__C2xCH PF09698.5 KEY72594.1 - 1.1 9.4 5.1 1.8 8.7 2.6 2.1 1 1 1 2 2 2 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) Ku_C PF03730.9 KEY72595.1 - 0.0041 17.6 3.3 0.008 16.6 2.3 1.5 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm DUF4206 PF13901.1 KEY72595.1 - 0.033 13.7 1.4 0.05 13.1 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) TMCO5 PF14992.1 KEY72595.1 - 0.089 11.9 9.5 0.068 12.2 2.3 2.0 1 1 1 2 2 2 0 TMCO5 family RF-1 PF00472.15 KEY72595.1 - 1.8 8.3 6.2 3.7 7.3 4.3 1.6 1 1 0 1 1 1 0 RF-1 domain PNP_UDP_1 PF01048.15 KEY72596.1 - 5.7e-07 28.7 1.9 5.1e-06 25.6 1.3 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_12 PF13424.1 KEY72597.1 - 8.2e-10 38.4 0.0 2e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 KEY72597.1 - 2.3e-08 33.6 0.1 0.00015 21.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat NB-ARC PF00931.17 KEY72597.1 - 2.5e-05 23.2 0.1 6e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain TPR_7 PF13176.1 KEY72597.1 - 0.00015 21.2 1.8 0.014 15.1 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEY72597.1 - 0.0002 21.0 0.2 0.18 11.7 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat NACHT PF05729.7 KEY72597.1 - 0.0019 17.8 0.0 0.0044 16.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_4 PF07721.9 KEY72597.1 - 0.011 16.1 0.5 4.9 7.8 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEY72597.1 - 0.014 15.8 0.2 1.5 9.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEY72597.1 - 0.015 15.9 0.7 6.4 7.7 0.0 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF1840 PF08895.6 KEY72598.1 - 0.26 11.3 3.9 0.7 9.9 0.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1840) DUF3669 PF12417.3 KEY72601.1 - 8.8e-23 79.8 0.3 1.9e-22 78.7 0.2 1.6 1 0 0 1 1 1 1 Zinc finger protein Acyl_transf_1 PF00698.16 KEY72604.1 - 0.00097 18.5 0.0 0.0011 18.3 0.0 1.1 1 0 0 1 1 1 1 Acyl transferase domain Tocopherol_cycl PF14249.1 KEY72605.1 - 0.045 12.4 0.0 0.055 12.1 0.0 1.0 1 0 0 1 1 1 0 Tocopherol cyclase dCMP_cyt_deam_1 PF00383.17 KEY72606.1 - 1.8e-10 40.3 1.6 4e-10 39.2 0.2 2.0 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region DDE_Tnp_1_7 PF13843.1 KEY72607.1 - 2.4e-08 33.4 0.0 2.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 COX2-transmemb PF09125.5 KEY72607.1 - 0.028 13.9 0.5 0.045 13.3 0.3 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane Glyco_hydro_3 PF00933.16 KEY72609.1 - 1.3e-53 181.9 0.0 1.8e-53 181.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY72609.1 - 1.2e-42 145.9 0.0 2.7e-42 144.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEY72609.1 - 9.5e-19 67.1 0.2 2e-18 66.0 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain KAAG1 PF15354.1 KEY72609.1 - 0.17 12.2 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Kidney-associated antigen 1 Zn_clus PF00172.13 KEY72610.1 - 4.7e-13 48.8 18.0 2.8e-08 33.5 4.6 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY72610.1 - 1.8e-11 43.4 0.2 1.8e-11 43.4 0.2 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain PHB_acc PF05233.8 KEY72610.1 - 0.44 10.3 1.2 0.89 9.3 0.8 1.5 1 0 0 1 1 1 0 PHB accumulation regulatory domain Sulfatase PF00884.18 KEY72611.1 - 3.7e-60 203.7 0.2 4.7e-60 203.3 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KEY72611.1 - 1.7e-10 40.7 0.5 4.1e-05 23.0 0.0 2.5 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KEY72611.1 - 0.0041 15.6 0.1 0.0087 14.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.7 KEY72611.1 - 0.038 12.8 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Sugar_tr PF00083.19 KEY72612.1 - 1.7e-99 333.4 22.9 4.3e-98 328.8 15.9 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY72612.1 - 4.1e-18 65.2 28.4 1e-15 57.3 11.1 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Pkinase PF00069.20 KEY72613.1 - 8.9e-28 97.1 0.0 1.2e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY72613.1 - 1.3e-17 63.7 0.0 2e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KEY72614.1 - 1.1e-19 70.5 0.0 2e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HET PF06985.6 KEY72614.1 - 6.2e-16 58.8 0.1 1.7e-15 57.4 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase_Tyr PF07714.12 KEY72614.1 - 1.5e-13 50.4 0.0 2.8e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KEY72614.1 - 0.088 11.5 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HD PF01966.17 KEY72617.1 - 0.00062 19.7 0.0 0.0014 18.5 0.0 1.7 1 1 0 1 1 1 1 HD domain Arylesterase PF01731.15 KEY72618.1 - 0.0092 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Arylesterase CP_ATPgrasp_2 PF14403.1 KEY72621.1 - 4.8e-06 25.5 0.0 0.00055 18.7 0.0 2.2 2 0 0 2 2 2 2 Circularly permuted ATP-grasp type 2 AMP-binding PF00501.23 KEY72621.1 - 0.062 11.6 0.0 0.11 10.9 0.0 1.3 1 0 0 1 1 1 0 AMP-binding enzyme Host_attach PF10116.4 KEY72621.1 - 0.1 12.7 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein required for attachment to host cells TauD PF02668.11 KEY72622.1 - 6.6e-21 75.1 1.7 8.5e-21 74.7 1.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KEY72622.1 - 0.0064 15.4 0.0 0.0085 15.0 0.0 1.2 1 0 0 1 1 1 1 CsiD ABC_tran PF00005.22 KEY72623.1 - 1.8e-44 151.3 0.0 1.1e-27 96.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEY72623.1 - 1.5e-24 86.9 11.0 1.5e-24 86.9 7.6 3.3 4 0 0 4 4 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KEY72623.1 - 2.7e-08 33.3 0.2 0.0054 15.9 0.0 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain T2SE PF00437.15 KEY72623.1 - 3.5e-06 26.1 0.0 0.069 12.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_21 PF13304.1 KEY72623.1 - 1.3e-05 25.3 0.2 0.18 11.6 0.0 3.5 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KEY72623.1 - 2.4e-05 23.9 0.0 0.45 9.9 0.0 3.3 3 0 0 3 3 3 1 AAA-like domain AAA_23 PF13476.1 KEY72623.1 - 0.00012 22.4 0.0 0.012 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEY72623.1 - 0.00012 21.5 0.1 0.18 11.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KEY72623.1 - 0.00033 19.8 0.1 0.27 10.2 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin MMR_HSR1 PF01926.18 KEY72623.1 - 0.00077 19.4 0.3 0.63 10.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KEY72623.1 - 0.0011 19.0 0.1 1.4 8.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KEY72623.1 - 0.0013 17.9 0.1 0.54 9.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEY72623.1 - 0.0014 18.7 0.0 4.5 7.4 0.0 3.3 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 KEY72623.1 - 0.0015 18.4 0.2 0.9 9.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 Miro PF08477.8 KEY72623.1 - 0.0019 18.6 1.2 2 8.9 0.0 3.0 4 0 0 4 4 2 2 Miro-like protein AAA PF00004.24 KEY72623.1 - 0.0029 17.7 0.0 6.5 6.9 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KEY72623.1 - 0.0067 15.8 2.2 0.85 8.9 0.0 3.1 4 0 0 4 4 4 1 AAA domain Dynamin_N PF00350.18 KEY72623.1 - 0.013 15.2 0.9 0.63 9.8 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AAA_17 PF13207.1 KEY72623.1 - 0.015 16.1 0.0 0.9 10.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KEY72623.1 - 0.034 13.1 0.7 1.6 7.6 0.0 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 KEY72623.1 - 0.053 12.9 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 KEY72623.1 - 0.091 12.2 0.0 5.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 KEY72623.1 - 0.3 11.3 0.0 17 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Na_H_Exchanger PF00999.16 KEY72624.1 - 2.1e-35 121.9 30.2 3e-28 98.4 15.2 3.1 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family Glyco_hydro_61 PF03443.9 KEY72625.1 - 6.4e-67 225.5 0.1 7.2e-67 225.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 KEY72625.1 - 0.051 13.6 0.1 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Sugar_tr PF00083.19 KEY72626.1 - 1.9e-92 310.2 20.1 2.1e-92 310.0 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY72626.1 - 2.3e-28 98.9 36.4 3.8e-22 78.4 10.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KEY72626.1 - 5.4e-05 21.5 0.9 5.4e-05 21.5 0.6 2.2 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Tannase PF07519.6 KEY72627.1 - 3.6e-73 246.9 0.0 4.4e-73 246.6 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 KEY72627.1 - 9.9e-06 25.5 0.0 0.00015 21.7 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY72627.1 - 0.019 14.5 0.1 0.038 13.5 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY72627.1 - 0.067 12.9 0.4 0.85 9.3 0.3 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family AMP-binding PF00501.23 KEY72628.1 - 2e-75 253.7 0.1 4.5e-75 252.5 0.1 1.6 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KEY72628.1 - 3.6e-58 197.0 0.1 6.6e-58 196.1 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KEY72628.1 - 9.7e-49 165.4 0.0 4.9e-46 156.6 0.0 2.8 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 KEY72628.1 - 3.3e-47 161.3 0.1 3.3e-47 161.3 0.1 1.6 2 0 0 2 2 1 1 Acyl transferase domain adh_short PF00106.20 KEY72628.1 - 8.7e-44 149.3 0.0 8.8e-39 133.0 0.0 2.9 2 0 0 2 2 2 2 short chain dehydrogenase Condensation PF00668.15 KEY72628.1 - 3.2e-42 144.4 0.0 5.4e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.1 KEY72628.1 - 5e-35 121.0 0.0 1.1e-34 119.9 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KEY72628.1 - 6.1e-30 103.5 0.1 3.4e-29 101.1 0.0 2.4 3 0 0 3 3 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KEY72628.1 - 9.4e-29 100.0 0.0 2.4e-28 98.7 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KEY72628.1 - 1.8e-15 56.9 2.4 9.3e-09 35.4 0.1 3.3 3 0 0 3 3 3 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 KEY72628.1 - 8.7e-13 48.5 0.0 5.1e-12 46.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 KEY72628.1 - 3.2e-12 46.4 0.0 9.3e-12 44.8 0.0 1.8 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HxxPF_rpt PF13745.1 KEY72628.1 - 4.8e-10 39.6 0.4 3.7e-09 36.7 0.0 2.6 2 0 0 2 2 2 1 HxxPF-repeated domain Methyltransf_31 PF13847.1 KEY72628.1 - 5e-08 32.6 0.0 2.7e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY72628.1 - 2e-07 30.8 0.0 6.3e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY72628.1 - 1.4e-06 28.8 0.0 3.8e-05 24.2 0.0 3.1 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY72628.1 - 3.5e-06 27.4 0.0 1.3e-05 25.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain AMP-binding_C PF13193.1 KEY72628.1 - 5.5e-05 24.0 0.0 0.00065 20.5 0.0 2.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 KEY72628.1 - 8.2e-05 21.4 0.0 0.00041 19.1 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.1 KEY72628.1 - 0.00043 20.5 0.0 0.0016 18.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY72628.1 - 0.014 14.5 0.0 0.2 10.7 0.0 2.4 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 KEY72628.1 - 0.037 13.0 0.0 0.1 11.6 0.0 1.6 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Semialdhyde_dh PF01118.19 KEY72628.1 - 0.12 12.6 0.2 2.2 8.6 0.0 2.9 3 0 0 3 3 2 0 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_32 PF13679.1 KEY72628.1 - 0.18 11.5 0.0 3.9 7.1 0.0 2.7 3 0 0 3 3 2 0 Methyltransferase domain Methyltransf_16 PF10294.4 KEY72628.1 - 0.26 10.7 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase DUF690 PF05108.8 KEY72629.1 - 0.0093 14.3 0.1 0.014 13.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF690) Zn_clus PF00172.13 KEY72629.1 - 0.05 13.5 13.2 0.088 12.7 9.2 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain LrgB PF04172.11 KEY72630.1 - 0.85 8.7 7.7 0.055 12.6 1.0 2.1 2 1 0 2 2 2 0 LrgB-like family p450 PF00067.17 KEY72631.1 - 2.2e-38 131.9 0.0 3e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KEY72632.1 - 9.9e-40 136.3 48.4 8.2e-39 133.3 33.5 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY72632.1 - 2.3e-10 39.6 18.0 2.3e-10 39.6 12.4 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter DUF1914 PF08932.5 KEY72632.1 - 0.015 15.2 0.1 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1914) DUF2530 PF10745.4 KEY72632.1 - 4.1 7.4 15.7 0.057 13.3 0.9 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) ADH_zinc_N PF00107.21 KEY72633.1 - 2.3e-11 43.3 0.0 4.1e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY72633.1 - 8.5e-06 25.4 0.1 5.7e-05 22.8 0.1 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain HlyIII PF03006.15 KEY72634.1 - 1.4e-24 86.8 9.1 1.5e-24 86.6 6.3 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF4149 PF13664.1 KEY72634.1 - 0.43 10.6 3.3 0.23 11.5 0.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) LrgA PF03788.9 KEY72635.1 - 0.012 15.2 0.0 0.052 13.2 0.0 2.1 1 0 0 1 1 1 0 LrgA family p450 PF00067.17 KEY72636.1 - 5.7e-40 137.1 0.0 7.1e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 KEY72637.1 - 2.1e-80 270.5 23.3 2.5e-80 270.2 16.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY72637.1 - 1.7e-12 46.7 54.4 7.4e-12 44.6 22.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KEY72638.1 - 1.6e-34 119.1 27.9 1.6e-34 119.1 19.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY72638.1 - 1.2e-07 30.6 30.6 2.5e-07 29.6 21.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter XhlA PF10779.4 KEY72638.1 - 0.24 11.3 0.9 2.6 8.0 0.6 2.5 2 0 0 2 2 2 0 Haemolysin XhlA FPN1 PF06963.7 KEY72639.1 - 8.2e-110 367.1 20.8 1e-109 366.8 14.4 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Tmemb_18A PF09771.4 KEY72639.1 - 8 6.4 9.9 1.2 9.1 0.2 3.1 3 0 0 3 3 3 0 Transmembrane protein 188 HET PF06985.6 KEY72640.1 - 7.7e-29 100.6 0.0 1.2e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 KEY72641.1 - 4e-15 55.2 0.0 5.2e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 KEY72642.1 - 2.8e-62 210.4 0.1 5e-62 209.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KEY72642.1 - 5.4e-36 123.0 0.1 5.4e-36 123.0 0.0 2.4 3 0 0 3 3 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KEY72642.1 - 3.5e-21 75.8 0.0 5.7e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KEY72642.1 - 4.3e-16 59.0 0.6 1e-15 57.8 0.4 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KEY72642.1 - 2.4e-14 53.6 0.8 5.2e-14 52.5 0.5 1.5 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 KEY72642.1 - 3.5e-08 34.4 0.0 9.3e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KEY72642.1 - 2.6e-07 30.2 0.0 7.8e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Abhydrolase_6 PF12697.2 KEY72642.1 - 0.00023 21.1 0.0 0.00072 19.5 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY72642.1 - 0.0022 17.7 0.3 0.013 15.2 0.2 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 KEY72642.1 - 0.0091 15.0 0.0 0.026 13.5 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.10 KEY72642.1 - 0.03 13.2 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF2974 PF11187.3 KEY72642.1 - 0.11 11.7 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) ThiF PF00899.16 KEY72642.1 - 0.14 11.9 0.2 0.41 10.4 0.1 1.8 1 0 0 1 1 1 0 ThiF family Myc_N PF01056.13 KEY72643.1 - 0.052 12.7 1.6 0.053 12.6 1.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Pox_RNA_Pol_19 PF05320.7 KEY72643.1 - 0.11 12.2 1.1 0.14 11.8 0.8 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DDE_Tnp_4 PF13359.1 KEY72644.1 - 1.5e-26 92.8 0.0 3.7e-26 91.6 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 KEY72644.1 - 6.1e-09 35.7 0.1 1.5e-07 31.2 0.0 2.4 1 1 0 1 1 1 1 Transposase DDE domain YPEB PF14620.1 KEY72644.1 - 0.0049 15.9 1.2 1.2 8.0 0.0 2.1 2 0 0 2 2 2 2 YpeB sporulation DUF4018 PF13210.1 KEY72644.1 - 0.032 13.6 0.0 0.095 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4018) Metal_resist PF13801.1 KEY72644.1 - 0.053 13.5 0.2 15 5.6 0.0 2.4 2 0 0 2 2 2 0 Heavy-metal resistance Chal_sti_synt_N PF00195.14 KEY72645.1 - 6.9e-22 77.7 0.1 1e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.7 KEY72645.1 - 1e-07 31.3 0.0 1.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein DUF3435 PF11917.3 KEY72646.1 - 0.0019 17.0 1.6 0.0033 16.2 1.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) Chromo PF00385.19 KEY72647.1 - 0.058 13.0 0.4 0.086 12.5 0.3 1.3 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain bZIP_1 PF00170.16 KEY72649.1 - 6.3e-09 35.6 5.1 6.3e-09 35.6 3.5 1.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KEY72649.1 - 9.9e-06 25.2 7.2 9.9e-06 25.2 5.0 1.9 2 1 0 2 2 2 1 Basic region leucine zipper Troponin PF00992.15 KEY72649.1 - 0.0023 18.0 7.3 0.0034 17.4 5.0 1.2 1 0 0 1 1 1 1 Troponin bZIP_Maf PF03131.12 KEY72649.1 - 0.0061 16.8 11.9 0.016 15.4 8.3 1.7 1 1 0 1 1 1 1 bZIP Maf transcription factor CAF-1_p150 PF11600.3 KEY72649.1 - 0.013 14.8 11.3 0.016 14.6 7.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TMF_DNA_bd PF12329.3 KEY72649.1 - 0.014 15.2 3.0 0.014 15.2 2.0 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 KEY72649.1 - 0.046 13.3 2.5 0.064 12.8 1.8 1.3 1 0 0 1 1 1 0 IncA protein Tup_N PF08581.5 KEY72649.1 - 0.52 10.5 6.8 0.28 11.4 3.4 1.5 1 1 0 1 1 1 0 Tup N-terminal DUF342 PF03961.8 KEY72649.1 - 0.66 8.3 3.6 0.68 8.2 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Ribosomal_L30_N PF08079.7 KEY72649.1 - 6.1 6.9 11.8 0.22 11.5 3.0 2.0 1 1 1 2 2 2 0 Ribosomal L30 N-terminal domain HisKA PF00512.20 KEY72650.1 - 1.6e-08 34.4 0.0 3.9e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 KEY72650.1 - 0.00034 20.9 0.0 0.00089 19.6 0.0 1.8 1 1 0 1 1 1 1 PAS domain DUF2884 PF11101.3 KEY72651.1 - 0.0039 16.6 0.4 0.006 15.9 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) GBP_C PF02841.9 KEY72651.1 - 0.015 14.5 3.7 0.019 14.1 2.5 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Transcrip_act PF04949.8 KEY72651.1 - 0.019 14.5 0.6 0.025 14.1 0.4 1.3 1 0 0 1 1 1 0 Transcriptional activator Apolipoprotein PF01442.13 KEY72651.1 - 0.048 13.1 2.9 0.069 12.6 2.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 KEY72651.1 - 0.61 9.8 4.1 0.14 11.9 0.3 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HSP70 PF00012.15 KEY72652.1 - 1.2e-26 92.7 8.5 2.9e-26 91.5 0.0 3.0 3 0 0 3 3 3 2 Hsp70 protein StbA PF06406.6 KEY72652.1 - 0.091 11.6 0.0 0.33 9.8 0.0 1.8 2 0 0 2 2 2 0 StbA protein CDC45 PF02724.9 KEY72652.1 - 0.34 8.8 10.5 0.4 8.6 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KEY72652.1 - 0.79 7.5 12.2 1.1 7.1 8.5 1.1 1 0 0 1 1 1 0 Nop14-like family MtmB PF05369.7 KEY72653.1 - 0.006 14.8 0.0 0.013 13.6 0.0 1.5 2 0 0 2 2 2 1 Monomethylamine methyltransferase MtmB DUF2884 PF11101.3 KEY72654.1 - 0.00092 18.6 0.9 0.0011 18.3 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) GBP_C PF02841.9 KEY72654.1 - 0.011 14.9 3.5 0.013 14.7 2.5 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Transcrip_act PF04949.8 KEY72654.1 - 0.015 14.9 0.3 0.017 14.7 0.2 1.2 1 0 0 1 1 1 0 Transcriptional activator Baculo_PEP_C PF04513.7 KEY72654.1 - 0.025 14.3 0.2 0.041 13.7 0.1 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 KEY72654.1 - 0.03 13.8 2.8 0.038 13.5 1.9 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Hemagglutinin PF00509.13 KEY72654.1 - 0.064 11.3 1.6 1.7 6.6 0.0 2.0 1 1 1 2 2 2 0 Haemagglutinin FliD_C PF07195.7 KEY72654.1 - 0.091 12.0 0.1 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus NolV PF06635.7 KEY72654.1 - 0.17 11.0 3.3 0.5 9.4 0.3 2.0 1 1 1 2 2 2 0 Nodulation protein NolV Cauli_DNA-bind PF03310.8 KEY72654.1 - 2.1 8.1 5.4 1.7 8.4 1.4 2.4 2 1 0 2 2 2 0 Caulimovirus DNA-binding protein PcfK PF14058.1 KEY72655.1 - 0.0033 17.5 3.3 0.0039 17.3 2.3 1.2 1 0 0 1 1 1 1 PcfK-like protein CDC45 PF02724.9 KEY72655.1 - 0.59 8.1 5.9 0.54 8.2 4.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Striatin PF08232.7 KEY72655.1 - 1.8 8.8 6.9 2.2 8.5 4.8 1.2 1 0 0 1 1 1 0 Striatin family HSP70 PF00012.15 KEY72656.1 - 7.5e-25 86.8 0.0 1.1e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein StbA PF06406.6 KEY72656.1 - 0.034 13.0 0.0 0.07 12.0 0.0 1.5 1 0 0 1 1 1 0 StbA protein p450 PF00067.17 KEY72657.1 - 1.2e-11 43.8 0.0 9e-11 40.9 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KEY72659.1 - 1.9e-51 175.0 0.0 2.6e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Dimerisation PF08100.6 KEY72659.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain adh_short PF00106.20 KEY72660.1 - 3.2e-15 56.4 4.0 2.6e-13 50.2 0.3 2.5 2 1 0 2 2 2 2 short chain dehydrogenase ADH_zinc_N PF00107.21 KEY72660.1 - 0.0006 19.3 0.1 0.19 11.2 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase KR PF08659.5 KEY72660.1 - 0.0011 18.7 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY72660.1 - 0.008 15.9 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase HTH_Tnp_Tc3_2 PF01498.13 KEY72661.1 - 2.2e-11 43.6 0.7 2.8e-11 43.3 0.5 1.1 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.1 KEY72661.1 - 0.02 14.8 0.7 0.042 13.8 0.5 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma_1s PF02454.11 KEY72661.1 - 0.02 14.6 0.1 0.027 14.2 0.1 1.2 1 0 0 1 1 1 0 Sigma 1s protein HTH_23 PF13384.1 KEY72661.1 - 0.023 14.3 1.1 0.023 14.3 0.8 1.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_29 PF13551.1 KEY72661.1 - 0.08 13.0 0.4 0.12 12.5 0.3 1.3 1 1 0 1 1 1 0 Winged helix-turn helix DUF851 PF05867.6 KEY72661.1 - 0.1 11.8 0.1 0.17 11.1 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF851) Peptidase_M14 PF00246.19 KEY72662.1 - 7.3e-43 147.1 0.5 9.1e-43 146.8 0.3 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase GATase PF00117.23 KEY72663.1 - 3.3e-05 23.4 0.0 6.8e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I p450 PF00067.17 KEY72664.1 - 3.4e-68 230.2 0.0 3.9e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.18 KEY72667.1 - 2.1e-76 256.9 36.9 1.2e-38 133.1 12.5 3.1 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KEY72667.1 - 1.9e-68 229.0 0.0 4.7e-34 117.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KEY72667.1 - 3.1e-15 56.0 0.1 3.5e-05 23.1 0.0 4.1 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEY72667.1 - 5.5e-13 49.5 0.0 0.04 13.8 0.1 4.5 3 1 1 4 4 4 4 AAA domain ABC_ATPase PF09818.4 KEY72667.1 - 2.5e-11 42.8 0.4 0.00093 17.8 0.0 4.1 4 0 0 4 4 4 3 Predicted ATPase of the ABC class AAA_29 PF13555.1 KEY72667.1 - 9.3e-09 34.6 0.7 0.00014 21.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KEY72667.1 - 2.3e-08 34.2 3.4 0.0013 18.7 0.5 3.0 2 2 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 KEY72667.1 - 9.8e-08 32.8 0.0 0.0067 17.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KEY72667.1 - 1e-07 31.2 0.0 0.012 14.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEY72667.1 - 1.5e-07 31.6 0.5 0.0054 16.8 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KEY72667.1 - 8.1e-07 28.6 0.7 0.065 12.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.1 KEY72667.1 - 5.4e-06 26.1 0.5 3.4 7.2 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 KEY72667.1 - 4.9e-05 23.6 0.0 0.59 10.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KEY72667.1 - 6e-05 23.4 0.2 0.0072 16.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KEY72667.1 - 9.6e-05 22.5 0.9 2 8.6 0.0 5.0 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KEY72667.1 - 0.00024 20.9 0.0 0.78 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KEY72667.1 - 0.00027 20.7 0.4 1.2 9.0 0.1 3.5 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 KEY72667.1 - 0.00077 19.4 0.1 2 8.3 0.0 3.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 KEY72667.1 - 0.00077 19.1 0.0 0.82 9.3 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KEY72667.1 - 0.0013 18.7 0.0 0.88 9.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KEY72667.1 - 0.003 17.4 0.0 5 7.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 KEY72667.1 - 0.0044 16.8 0.1 4 7.1 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 KEY72667.1 - 0.0096 15.3 0.3 0.91 8.8 0.1 2.9 3 0 0 3 3 2 1 AAA-like domain AAA_5 PF07728.9 KEY72667.1 - 0.011 15.4 0.0 8.6 6.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Nuc_deoxyrib_tr PF05014.10 KEY72667.1 - 0.015 15.2 0.1 8.7 6.2 0.0 2.9 3 0 0 3 3 2 0 Nucleoside 2-deoxyribosyltransferase RNA_helicase PF00910.17 KEY72667.1 - 0.02 15.0 0.0 4.6 7.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.1 KEY72667.1 - 0.022 13.8 0.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 KEY72667.1 - 0.039 13.6 0.1 0.91 9.3 0.1 3.0 2 0 0 2 2 2 0 Part of AAA domain Zeta_toxin PF06414.7 KEY72667.1 - 0.049 12.7 0.2 17 4.4 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin Rad17 PF03215.10 KEY72667.1 - 0.082 11.5 0.1 5 5.6 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DUF3987 PF13148.1 KEY72667.1 - 0.093 11.2 0.0 8.1 4.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) ATP_bind_1 PF03029.12 KEY72667.1 - 0.097 12.1 0.1 3.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.17 KEY72667.1 - 0.18 10.6 0.3 9.9 4.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain G-alpha PF00503.15 KEY72667.1 - 0.19 10.3 0.0 11 4.5 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Fungal_trans PF04082.13 KEY72668.1 - 1.3e-09 37.3 0.0 3.2e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Melibiase PF02065.13 KEY72669.1 - 6e-23 81.1 0.2 1.3e-15 56.9 0.0 2.8 2 1 0 2 2 2 2 Melibiase DUF4387 PF14330.1 KEY72670.1 - 1.9e-30 105.0 0.0 3.6e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 KEY72670.1 - 5.1e-11 41.6 0.0 2.2e-10 39.5 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1446) PAD PF03068.10 KEY72671.1 - 5.5e-54 183.0 0.0 2.3e-35 121.7 0.0 2.3 1 1 0 2 2 2 2 Protein-arginine deiminase (PAD) Glyco_hydro_61 PF03443.9 KEY72672.1 - 5.3e-64 216.0 0.0 6e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 6PGD PF00393.14 KEY72673.1 - 5.8e-65 219.3 0.0 7.2e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KEY72673.1 - 8.5e-30 103.7 0.0 7.9e-28 97.3 0.0 2.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KEY72673.1 - 1.6e-07 31.1 0.0 3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KEY72673.1 - 1.1e-05 24.6 0.0 1.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_Gly3P_dh_N PF01210.18 KEY72673.1 - 1.9e-05 24.4 0.0 5.8e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 KEY72673.1 - 0.00027 21.2 0.0 0.0017 18.7 0.0 2.2 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 KEY72673.1 - 0.00059 19.0 0.0 0.0013 17.9 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KEY72673.1 - 0.00071 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 KEY72673.1 - 0.014 14.8 0.0 0.034 13.6 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Con-6 PF10346.4 KEY72674.1 - 7.3e-15 54.0 0.9 1.3e-14 53.3 0.6 1.4 1 0 0 1 1 1 1 Conidiation protein 6 PHD PF00628.24 KEY72676.1 - 0.0027 17.3 1.4 0.0067 16.1 1.0 1.7 1 0 0 1 1 1 1 PHD-finger FANCL_C PF11793.3 KEY72676.1 - 0.023 14.6 2.0 0.069 13.1 1.4 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain APP_N PF02177.11 KEY72676.1 - 0.067 13.1 0.1 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding Zn_clus PF00172.13 KEY72677.1 - 0.00016 21.4 2.2 0.0003 20.6 1.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-Apc11 PF12861.2 KEY72679.1 - 3.9 7.3 6.7 2.3 8.1 0.3 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger CBM_1 PF00734.13 KEY72681.1 - 8.1e-13 47.7 5.7 2.4e-12 46.2 3.9 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL PF00657.17 KEY72681.1 - 7.7e-08 32.4 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SCA7 PF08313.7 KEY72681.1 - 0.078 12.5 0.2 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 SCA7, zinc-binding domain Zn_clus PF00172.13 KEY72682.1 - 7.5e-05 22.5 12.5 0.00012 21.9 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.17 KEY72682.1 - 0.9 8.4 5.6 1.8 7.4 3.9 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 KEY72682.1 - 1.2 7.9 14.9 0.55 9.0 7.8 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor FAD_binding_6 PF00970.19 KEY72684.1 - 5.1e-11 42.5 0.0 1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KEY72684.1 - 7.4e-10 39.3 0.0 1.9e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.17 KEY72684.1 - 1.5e-09 38.1 0.0 3.3e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Globin Protoglobin PF11563.3 KEY72684.1 - 5.4e-05 22.8 0.1 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.7 KEY72684.1 - 0.0027 17.6 0.3 0.019 14.8 0.1 2.4 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Glycos_transf_1 PF00534.15 KEY72686.1 - 3e-26 91.8 0.0 5.1e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KEY72686.1 - 2.5e-10 40.6 0.0 5.5e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KEY72686.1 - 1.8e-07 31.3 0.0 6.3e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Sod_Fe_C PF02777.13 KEY72687.1 - 8.7e-40 134.8 0.1 1.4e-39 134.1 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KEY72687.1 - 4.3e-32 110.2 0.6 7.2e-32 109.4 0.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Phage_capsid PF05065.8 KEY72687.1 - 0.11 11.6 0.2 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 Phage capsid family Sld5 PF05916.6 KEY72688.1 - 7.6e-10 39.0 0.0 1e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein TauD PF02668.11 KEY72689.1 - 8.4e-47 159.9 0.5 1.1e-46 159.6 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CaM-KIIN PF15170.1 KEY72691.1 - 0.089 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Calcium/calmodulin-dependent protein kinase II inhibitor PRKCSH PF07915.8 KEY72692.1 - 3.6e-17 62.9 0.0 1.3e-16 61.1 0.0 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Microtub_assoc PF07989.6 KEY72693.1 - 0.0007 19.3 0.5 0.0027 17.4 0.3 2.0 1 0 0 1 1 1 1 Microtubule associated DivIVA PF05103.8 KEY72693.1 - 0.035 14.1 3.5 0.11 12.5 2.5 1.8 1 0 0 1 1 1 0 DivIVA protein DUF1395 PF07160.7 KEY72693.1 - 0.039 13.4 1.2 0.072 12.5 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) DPBB_1 PF03330.13 KEY72694.1 - 9.3e-09 35.1 0.0 1.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KEY72694.1 - 0.00013 21.6 0.1 0.00018 21.1 0.1 1.2 1 0 0 1 1 1 1 Barwin family HET PF06985.6 KEY72696.1 - 2.5e-35 121.6 0.1 6.2e-35 120.3 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Mur_ligase_M PF08245.7 KEY72697.1 - 1.4e-07 31.7 0.0 9.8e-07 28.9 0.0 2.2 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.16 KEY72697.1 - 0.0085 16.1 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Abhydrolase_6 PF12697.2 KEY72698.1 - 4.6e-12 46.3 1.2 1.1e-11 45.0 0.8 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY72698.1 - 1.5e-11 44.2 0.1 2.9e-11 43.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KEY72698.1 - 1.2e-05 24.9 0.0 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KEY72698.1 - 0.04 13.7 0.1 0.1 12.4 0.0 1.7 1 1 0 1 1 1 0 Putative lysophospholipase Dynamin_N PF00350.18 KEY72700.1 - 2.5e-36 125.0 0.4 7.7e-36 123.4 0.0 2.0 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KEY72700.1 - 5.3e-18 64.8 0.0 1.8e-16 59.8 0.0 2.2 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 KEY72700.1 - 2.1e-05 24.4 0.0 0.00013 21.9 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEY72700.1 - 0.0014 19.1 0.7 0.018 15.5 0.0 2.7 3 0 0 3 3 3 1 Miro-like protein AAA_21 PF13304.1 KEY72700.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AHH PF14412.1 KEY72700.1 - 0.16 11.9 3.2 0.32 10.9 0.1 2.7 3 0 0 3 3 3 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Ribonuclease PF00545.15 KEY72701.1 - 3.3e-18 65.5 0.4 6.7e-18 64.5 0.2 1.5 1 1 1 2 2 2 1 ribonuclease MFS_1 PF07690.11 KEY72702.1 - 3.2e-33 114.9 34.3 8.8e-33 113.4 23.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1286 PF06939.6 KEY72702.1 - 0.22 11.6 2.9 0.54 10.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1286) AA_permease PF00324.16 KEY72704.1 - 3.6e-96 322.3 43.5 4.1e-96 322.1 30.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEY72704.1 - 1.7e-25 89.4 44.3 2.1e-25 89.1 30.7 1.0 1 0 0 1 1 1 1 Amino acid permease Esterase_phd PF10503.4 KEY72707.1 - 7e-21 74.4 0.5 1.1e-20 73.8 0.4 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KEY72707.1 - 2.3e-09 36.7 0.4 3.7e-09 36.1 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KEY72707.1 - 4.3e-07 30.0 3.6 9.2e-07 28.9 2.6 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY72707.1 - 6.6e-07 29.1 0.3 1e-06 28.5 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KEY72707.1 - 4e-05 23.1 0.2 6.2e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 KEY72707.1 - 0.00053 19.6 0.5 0.00084 18.9 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KEY72707.1 - 0.0023 17.5 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 KEY72707.1 - 0.0032 16.9 1.0 0.0065 15.9 0.5 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 KEY72707.1 - 0.053 12.9 0.0 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase AXE1 PF05448.7 KEY72707.1 - 0.055 11.9 0.1 0.083 11.3 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Utp12 PF04003.7 KEY72708.1 - 6.3e-22 77.5 0.0 9.2e-22 77.0 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family Bromodomain PF00439.20 KEY72709.1 - 3.8e-29 100.4 0.0 7.4e-15 54.6 0.0 2.7 2 0 0 2 2 2 2 Bromodomain NUDIX PF00293.23 KEY72710.1 - 7e-06 25.7 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain HSP70 PF00012.15 KEY72711.1 - 1.6e-07 29.6 0.1 8.3e-07 27.2 0.0 1.9 2 0 0 2 2 2 1 Hsp70 protein Trypan_PARP PF05887.6 KEY72711.1 - 0.00036 20.3 6.2 0.001 18.8 4.3 1.7 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) SET PF00856.23 KEY72711.1 - 0.0017 18.7 0.0 0.012 15.9 0.0 2.3 2 0 0 2 2 2 1 SET domain Pkinase PF00069.20 KEY72712.1 - 3.2e-59 200.1 0.0 4.7e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY72712.1 - 1.4e-32 112.7 0.0 5.9e-31 107.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KEY72712.1 - 0.012 14.4 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 KEY72712.1 - 0.14 11.2 0.3 0.27 10.2 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Stc1 PF12898.2 KEY72713.1 - 5.4e-11 42.4 5.2 8.7e-11 41.7 3.6 1.3 1 0 0 1 1 1 1 Stc1 domain DUF164 PF02591.10 KEY72713.1 - 0.00057 19.6 1.0 0.001 18.8 0.7 1.4 1 0 0 1 1 1 1 Putative zinc ribbon domain zf-CHY PF05495.7 KEY72713.1 - 0.036 14.2 1.4 0.065 13.3 1.0 1.3 1 0 0 1 1 1 0 CHY zinc finger FXR1P_C PF12235.3 KEY72713.1 - 0.38 10.8 4.5 0.077 13.0 0.6 1.7 2 0 0 2 2 2 0 Fragile X-related 1 protein C terminal BCDHK_Adom3 PF10436.4 KEY72714.1 - 3.2e-69 231.6 0.0 5.1e-69 230.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KEY72714.1 - 2.9e-17 62.3 0.0 6.4e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KEY72714.1 - 0.0066 16.1 0.0 0.02 14.5 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sorb PF02208.11 KEY72714.1 - 0.0084 15.4 0.1 0.18 11.2 0.0 2.6 2 0 0 2 2 2 1 Sorbin homologous domain Ribosomal_L22 PF00237.14 KEY72714.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e DUF1777 PF08648.7 KEY72715.1 - 0.15 11.7 5.0 0.28 10.9 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) GP41 PF00517.12 KEY72715.1 - 0.31 10.5 2.7 0.48 9.9 1.9 1.2 1 0 0 1 1 1 0 Retroviral envelope protein IncA PF04156.9 KEY72715.1 - 9.6 5.7 22.6 0.88 9.1 2.9 2.4 2 1 1 3 3 3 0 IncA protein CarD_CdnL_TRCF PF02559.11 KEY72716.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 CarD-like/TRCF domain Pyridoxal_deC PF00282.14 KEY72717.1 - 1e-20 73.5 0.0 1.5e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KEY72717.1 - 3.5e-06 26.0 0.0 7.7e-06 24.8 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KEY72717.1 - 2.4e-05 23.5 0.0 3.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_transf_34 PF05637.7 KEY72718.1 - 4.5e-69 232.5 0.0 5.6e-69 232.2 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family RINGv PF12906.2 KEY72719.1 - 6e-09 35.8 4.9 1.4e-08 34.6 0.9 2.2 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 KEY72719.1 - 0.0011 18.7 3.2 0.0045 16.7 0.8 2.2 2 0 0 2 2 2 1 Ring finger domain zf-MIZ PF02891.15 KEY72719.1 - 0.084 12.4 2.2 0.17 11.4 1.5 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger PHD PF00628.24 KEY72719.1 - 1.1 8.9 5.4 0.25 11.0 1.3 1.7 2 0 0 2 2 2 0 PHD-finger Proteasome PF00227.21 KEY72720.1 - 8.2e-56 188.3 0.1 2.6e-33 114.8 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KEY72720.1 - 1.9e-11 43.0 0.3 4.1e-11 41.9 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_S13 PF02113.10 KEY72720.1 - 0.18 10.3 0.5 4 5.8 0.1 2.2 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family RCC1_2 PF13540.1 KEY72721.1 - 4.3e-08 32.5 6.3 0.0003 20.3 0.1 3.9 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 KEY72721.1 - 1.2e-05 25.4 1.8 1.3 9.2 0.1 5.5 4 1 1 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.6 KEY72721.1 - 0.09 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split Ribonuclease_3 PF00636.21 KEY72722.1 - 1.2e-44 151.4 0.0 3.3e-23 82.3 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KEY72722.1 - 7.6e-25 87.3 0.0 1.3e-10 41.3 0.0 3.7 3 1 0 3 3 3 3 Ribonuclease-III-like DEAD PF00270.24 KEY72722.1 - 3.1e-21 75.5 0.0 6.2e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Dicer_dimer PF03368.9 KEY72722.1 - 2.4e-17 62.4 0.0 6e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 KEY72722.1 - 6.6e-17 61.1 0.0 1.5e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEY72722.1 - 1.2e-10 41.5 0.0 2.2e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 KEY72722.1 - 0.11 11.6 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.1 KEY72723.1 - 2.1e-07 31.7 0.0 4.1e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEY72723.1 - 5.6e-05 23.4 0.0 0.00012 22.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 KEY72723.1 - 0.00012 21.7 0.0 0.00023 20.8 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein PRK PF00485.13 KEY72723.1 - 0.0038 16.8 0.0 0.009 15.5 0.0 1.7 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 KEY72723.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KEY72723.1 - 0.037 14.5 0.0 0.059 13.8 0.0 1.3 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 KEY72723.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter PTH2 PF01981.11 KEY72724.1 - 1.7e-47 159.8 0.1 2.6e-47 159.3 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 BING4CT PF08149.6 KEY72725.1 - 5.1e-39 131.6 0.1 3.9e-36 122.4 0.0 3.3 4 0 0 4 4 4 2 BING4CT (NUC141) domain WD40 PF00400.27 KEY72725.1 - 4.6e-07 29.4 0.0 0.00028 20.6 0.0 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KEY72725.1 - 0.00012 21.0 0.1 0.015 14.0 0.0 2.2 2 0 0 2 2 2 2 Coatomer WD associated region DUF663 PF04950.7 KEY72726.1 - 1.9e-106 355.3 0.0 2.8e-106 354.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KEY72726.1 - 1.1e-19 69.7 0.0 2.6e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain cobW PF02492.14 KEY72727.1 - 1.8e-34 118.7 0.0 3.8e-34 117.6 0.0 1.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KEY72727.1 - 2.2e-06 26.6 0.1 0.0025 16.6 0.0 2.0 2 0 0 2 2 2 2 ArgK protein AAA_23 PF13476.1 KEY72727.1 - 0.016 15.5 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KEY72727.1 - 0.028 14.3 0.0 0.088 12.7 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.1 KEY72727.1 - 0.036 14.8 0.2 0.075 13.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KEY72727.1 - 0.049 13.0 0.4 0.086 12.2 0.3 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KEY72727.1 - 0.079 12.3 0.0 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_26 PF13500.1 KEY72727.1 - 0.099 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain KOW PF00467.24 KEY72728.1 - 0.13 12.0 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 KOW motif DUF4557 PF15101.1 KEY72728.1 - 0.27 11.0 5.9 0.32 10.7 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Ras PF00071.17 KEY72729.1 - 3e-51 173.0 0.0 8.1e-51 171.6 0.0 1.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KEY72729.1 - 5.6e-15 55.8 0.0 8.5e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEY72729.1 - 6.2e-06 25.5 0.0 1.8e-05 24.0 0.0 1.6 1 1 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.5 KEY72729.1 - 0.01 15.0 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KEY72729.1 - 0.034 13.3 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Aa_trans PF01490.13 KEY72730.1 - 1.6e-71 241.0 30.4 1.9e-71 240.7 21.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 KEY72730.1 - 0.038 12.5 34.5 0.9 8.0 23.9 2.1 1 1 0 1 1 1 0 Amino acid permease Asp PF00026.18 KEY72731.1 - 1.4e-63 215.1 0.2 1.7e-63 214.7 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEY72731.1 - 3.6e-08 33.5 1.1 1.3e-07 31.7 0.0 2.4 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KEY72731.1 - 2e-05 25.0 0.0 0.012 16.1 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease PPTA PF01239.17 KEY72733.1 - 4.5e-05 22.6 12.0 0.0096 15.2 0.5 4.7 5 0 0 5 5 5 3 Protein prenyltransferase alpha subunit repeat DUF3255 PF11631.3 KEY72733.1 - 0.17 11.5 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3255) CHD5 PF04420.9 KEY72734.1 - 4.6e-58 195.4 0.2 6.2e-58 195.0 0.1 1.2 1 0 0 1 1 1 1 CHD5-like protein PcfJ PF14284.1 KEY72734.1 - 0.034 13.6 0.2 0.048 13.1 0.1 1.2 1 0 0 1 1 1 0 PcfJ-like protein DUF1515 PF07439.6 KEY72734.1 - 0.082 12.7 0.6 0.19 11.5 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) MADF_DNA_bdg PF10545.4 KEY72734.1 - 0.55 10.4 3.5 1.2 9.3 2.4 1.7 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TrbC PF04956.8 KEY72735.1 - 0.087 12.8 5.8 1.5 8.9 0.3 3.2 3 0 0 3 3 3 0 TrbC/VIRB2 family DUF1772 PF08592.6 KEY72735.1 - 0.099 12.3 7.6 0.18 11.4 1.7 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) GRAB PF10375.4 KEY72736.1 - 6e-09 35.1 0.2 1.2e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain WEMBL PF05701.6 KEY72736.1 - 0.0013 17.3 21.9 0.0013 17.3 15.2 2.3 1 1 1 2 2 2 1 Weak chloroplast movement under blue light Filament PF00038.16 KEY72736.1 - 0.03 13.8 50.6 0.43 9.9 9.7 2.5 1 1 1 2 2 2 0 Intermediate filament protein CENP-F_leu_zip PF10473.4 KEY72736.1 - 0.49 10.2 57.4 0.14 12.0 12.5 3.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Transposase_22 PF02994.9 KEY72736.1 - 0.54 8.6 39.4 0.13 10.7 13.0 3.2 1 1 2 3 3 3 0 L1 transposable element NPV_P10 PF05531.7 KEY72736.1 - 1.2 9.4 17.4 0.33 11.2 0.9 3.9 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein ApoO PF09769.4 KEY72736.1 - 3 7.5 8.2 1.2 8.8 0.8 3.1 1 1 1 3 3 3 0 Apolipoprotein O Baculo_PEP_C PF04513.7 KEY72736.1 - 3.4 7.5 21.8 0.49 10.2 1.6 3.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 KEY72736.1 - 7.2 5.6 17.2 4.6 6.3 1.8 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein IncA PF04156.9 KEY72736.1 - 7.2 6.1 58.1 0.38 10.3 11.5 3.8 1 1 2 3 3 3 0 IncA protein RRM_1 PF00076.17 KEY72737.1 - 1.4e-16 59.8 0.0 3e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY72737.1 - 4.5e-12 45.7 0.0 9.3e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY72737.1 - 2.8e-10 39.8 0.1 5.6e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KEY72737.1 - 0.035 13.8 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 SMN PF06003.7 KEY72738.1 - 2.7e-10 39.7 5.7 1.3e-08 34.3 0.4 2.0 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) Cu_bind_like PF02298.12 KEY72739.1 - 0.031 14.0 0.3 0.24 11.2 0.2 2.1 1 1 0 1 1 1 0 Plastocyanin-like domain IER PF05760.7 KEY72739.1 - 1 9.2 10.7 1 9.2 2.8 2.2 2 0 0 2 2 2 0 Immediate early response protein (IER) VHS PF00790.14 KEY72741.1 - 2.3e-06 27.2 0.0 1e-05 25.2 0.0 2.0 2 1 1 3 3 3 1 VHS domain CTD_bind PF04818.8 KEY72741.1 - 0.00027 21.1 0.0 0.00059 20.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf-C2H2_4 PF13894.1 KEY72741.1 - 0.027 14.7 3.7 4.9 7.7 0.3 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KEY72741.1 - 0.2 11.3 5.3 2 8.1 0.8 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type RRN7 PF11781.3 KEY72741.1 - 0.35 10.3 3.2 1 8.9 0.3 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-H2C2_2 PF13465.1 KEY72741.1 - 3.4 8.1 4.4 33 5.0 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double domain MgsA_C PF12002.3 KEY72742.1 - 2.2e-61 206.4 0.0 4.3e-61 205.4 0.0 1.5 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 KEY72742.1 - 2.2e-13 50.5 0.0 4.2e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KEY72742.1 - 4.6e-10 38.9 0.0 5.4e-09 35.4 0.0 2.0 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KEY72742.1 - 8.3e-06 25.9 3.2 0.003 17.5 0.0 3.5 2 2 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KEY72742.1 - 1.2e-05 25.4 0.2 5.4e-05 23.3 0.0 2.3 2 1 0 2 2 1 1 AAA domain Sigma54_activat PF00158.21 KEY72742.1 - 1.4e-05 24.6 0.0 0.00049 19.6 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.1 KEY72742.1 - 3e-05 23.9 0.0 5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEY72742.1 - 7.1e-05 22.5 0.1 0.0017 18.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KEY72742.1 - 8e-05 21.8 0.1 0.18 10.9 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KEY72742.1 - 0.00027 20.6 0.4 0.0011 18.6 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain DUF815 PF05673.8 KEY72742.1 - 0.00044 19.2 0.0 0.00068 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 KEY72742.1 - 0.0018 17.0 0.0 0.033 12.9 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_3 PF07726.6 KEY72742.1 - 0.0029 17.2 0.0 0.0065 16.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 KEY72742.1 - 0.004 17.0 0.1 2.7 7.7 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DNA_pol3_delta2 PF13177.1 KEY72742.1 - 0.0076 15.9 0.0 2.1 7.9 0.0 2.8 2 1 1 3 3 3 1 DNA polymerase III, delta subunit AAA_10 PF12846.2 KEY72742.1 - 0.058 12.8 0.4 9.9 5.4 0.1 2.7 2 1 0 2 2 2 0 AAA-like domain Sigma54_activ_2 PF14532.1 KEY72742.1 - 0.064 13.3 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.1 KEY72742.1 - 0.074 13.3 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 KEY72742.1 - 0.08 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase NB-ARC PF00931.17 KEY72742.1 - 0.081 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 KEY72742.1 - 0.087 13.6 0.0 0.18 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KEY72742.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 KEY72742.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 KEY72742.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein zf-TRAF PF02176.13 KEY72742.1 - 0.13 12.6 0.2 0.23 11.8 0.1 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger CDC27 PF09507.5 KEY72742.1 - 2.4 7.2 5.0 3.3 6.8 3.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 XPG_I PF00867.13 KEY72743.1 - 8.2e-27 93.1 0.0 1.7e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KEY72743.1 - 0.00059 20.0 0.0 0.0015 18.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain tRNA-synt_2b PF00587.20 KEY72744.1 - 1.4e-22 80.1 0.0 2e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Actin PF00022.14 KEY72744.1 - 2.9e-19 68.7 0.0 1.1e-18 66.8 0.0 1.9 2 0 0 2 2 2 1 Actin Seryl_tRNA_N PF02403.17 KEY72744.1 - 5.5e-10 39.2 2.6 1e-09 38.3 1.8 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 KEY72744.1 - 0.018 14.6 1.0 0.018 14.6 0.7 1.6 2 0 0 2 2 2 0 Mnd1 family CorA PF01544.13 KEY72745.1 - 0.17 10.8 0.6 0.57 9.1 0.4 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Pkinase PF00069.20 KEY72746.1 - 4.2e-71 239.1 0.0 1.2e-70 237.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY72746.1 - 5.1e-30 104.4 0.0 1e-21 77.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEY72746.1 - 8.3e-06 24.9 0.0 0.4 9.6 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 KEY72746.1 - 0.034 13.2 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C2H2_4 PF13894.1 KEY72748.1 - 0.052 13.8 1.3 9.4 6.8 0.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger AT_hook PF02178.14 KEY72748.1 - 0.15 11.8 15.4 0.12 12.0 3.1 2.8 2 0 0 2 2 2 0 AT hook motif GFA PF04828.9 KEY72749.1 - 2.9e-09 36.7 0.4 2.9e-09 36.7 0.3 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DUF2661 PF10860.3 KEY72749.1 - 0.0007 19.7 0.0 0.001 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2661) A2L_zn_ribbon PF08792.5 KEY72749.1 - 0.0032 16.8 0.2 0.0032 16.8 0.1 2.3 3 0 0 3 3 3 1 A2L zinc ribbon domain zf-ribbon_3 PF13248.1 KEY72749.1 - 0.0054 15.9 1.3 0.013 14.7 0.1 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KEY72749.1 - 0.048 13.1 0.2 0.048 13.1 0.1 2.3 3 0 0 3 3 3 0 zinc-ribbon domain Yippee-Mis18 PF03226.9 KEY72749.1 - 0.19 11.7 1.8 0.46 10.5 1.3 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Cys_rich_CWC PF14375.1 KEY72749.1 - 0.95 9.4 5.2 2.8 7.9 0.2 2.7 2 1 1 3 3 3 0 Cysteine-rich CWC C2 PF00168.25 KEY72750.1 - 7.6e-21 73.7 0.0 1.2e-14 53.8 0.0 2.7 2 0 0 2 2 2 2 C2 domain adh_short PF00106.20 KEY72751.1 - 1.3e-15 57.6 14.4 4.1e-14 52.8 10.0 2.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY72751.1 - 8.5e-12 45.3 0.7 4.7e-11 42.9 0.5 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY72751.1 - 1.1e-09 38.1 3.3 1.1e-09 38.1 2.3 2.3 2 1 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 KEY72751.1 - 2.2e-05 24.5 0.2 3.4e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 KEY72751.1 - 0.23 11.9 4.0 0.1 13.0 0.6 2.0 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.11 KEY72753.1 - 1.9e-40 138.7 40.0 1.9e-40 138.7 27.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY72753.1 - 0.00025 19.7 33.2 0.0031 16.1 23.1 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.19 KEY72754.1 - 1.3e-109 366.7 28.0 1.7e-109 366.4 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY72754.1 - 2.3e-20 72.6 34.5 2.3e-20 72.6 23.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KEY72754.1 - 0.0099 15.6 2.1 0.06 13.1 0.1 2.8 2 0 0 2 2 2 1 MFS_1 like family DUF4157 PF13699.1 KEY72754.1 - 0.024 14.7 0.1 0.081 13.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) RskA PF10099.4 KEY72754.1 - 5.6 6.6 9.4 1.2 8.7 2.4 2.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Peptidase_C12 PF01088.16 KEY72755.1 - 1.5e-54 184.4 0.0 1.9e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyoxalase_2 PF12681.2 KEY72755.1 - 0.038 14.6 0.0 0.067 13.8 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain AIP3 PF03915.8 KEY72756.1 - 3.3e-158 527.0 7.3 5.3e-158 526.3 5.1 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.9 KEY72756.1 - 0.0058 16.0 2.0 0.018 14.4 0.1 2.8 2 0 0 2 2 2 1 Hepatic lectin, N-terminal domain FliL PF03748.9 KEY72756.1 - 0.0073 16.2 0.1 0.031 14.2 0.1 2.1 1 0 0 1 1 1 1 Flagellar basal body-associated protein FliL DUF1664 PF07889.7 KEY72756.1 - 0.016 15.0 7.2 0.038 13.7 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) GNVR PF13807.1 KEY72756.1 - 0.075 12.7 0.5 1.3 8.8 0.0 2.6 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase FH2 PF02181.18 KEY72756.1 - 0.093 11.5 2.3 0.23 10.2 0.8 2.2 2 0 0 2 2 2 0 Formin Homology 2 Domain NPV_P10 PF05531.7 KEY72756.1 - 2 8.7 9.0 0.78 10.0 0.0 3.8 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Syntaxin_2 PF14523.1 KEY72756.1 - 2.3 8.3 0.0 2.3 8.3 0.0 4.8 6 1 0 6 6 6 0 Syntaxin-like protein IKI3 PF04762.7 KEY72757.1 - 0 1041.2 0.0 0 1034.3 0.0 2.0 1 1 0 1 1 1 1 IKI3 family TPR_8 PF13181.1 KEY72757.1 - 0.15 11.8 0.6 1.1 9.2 0.1 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF3984 PF13136.1 KEY72758.1 - 1.4e-71 241.4 17.3 1.8e-71 241.0 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) RAP1 PF07218.6 KEY72758.1 - 1.5 6.8 3.2 2 6.4 2.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Hpt PF01627.18 KEY72759.1 - 4.3e-13 49.0 0.0 5.7e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Hpt domain Ribonuc_L-PSP PF01042.16 KEY72759.1 - 0.013 15.3 0.0 0.39 10.4 0.0 2.1 1 1 0 2 2 2 0 Endoribonuclease L-PSP AKAP7_NLS PF10469.4 KEY72760.1 - 1.8e-29 102.9 0.0 2e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Angiomotin_C PF12240.3 KEY72761.1 - 0.00035 20.1 8.3 0.00077 19.0 5.7 1.5 1 0 0 1 1 1 1 Angiomotin C terminal CENP-Q PF13094.1 KEY72761.1 - 0.001 19.1 15.7 0.015 15.3 3.6 2.4 1 1 1 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Sec2p PF06428.6 KEY72761.1 - 0.018 14.9 5.1 1.5 8.6 0.0 2.7 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p ADIP PF11559.3 KEY72761.1 - 0.019 14.9 7.6 0.036 13.9 5.3 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.3 KEY72761.1 - 0.019 14.7 13.8 0.07 12.8 4.0 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.4 KEY72761.1 - 0.03 13.2 4.0 0.067 12.1 2.8 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin_1 PF12718.2 KEY72761.1 - 0.048 13.5 12.5 0.094 12.5 8.7 1.4 1 0 0 1 1 1 0 Tropomyosin like Bacillus_HBL PF05791.6 KEY72761.1 - 0.048 13.0 0.9 8.2 5.7 0.1 3.0 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) V_ATPase_I PF01496.14 KEY72761.1 - 0.1 10.4 5.0 0.2 9.4 2.8 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF4201 PF13870.1 KEY72761.1 - 0.23 10.9 6.9 0.99 8.8 3.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DivIC PF04977.10 KEY72761.1 - 0.31 10.5 6.3 3.8 7.0 1.3 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF4407 PF14362.1 KEY72761.1 - 0.36 9.7 7.8 0.65 8.8 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mnd1 PF03962.10 KEY72761.1 - 0.59 9.7 7.8 0.15 11.6 3.1 1.7 2 0 0 2 2 2 0 Mnd1 family TMF_DNA_bd PF12329.3 KEY72761.1 - 1.2 8.9 8.6 8.2 6.3 3.1 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Cep57_MT_bd PF06657.8 KEY72761.1 - 5.1 7.1 7.5 3.7 7.5 0.9 2.9 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 APG6 PF04111.7 KEY72761.1 - 7.4 5.5 11.0 3 6.7 5.2 1.8 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF641 PF04859.7 KEY72761.1 - 8.3 6.1 11.3 4.2 7.1 1.2 2.7 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Menin PF05053.8 KEY72762.1 - 0.33 9.0 3.9 0.33 9.0 2.7 1.1 1 0 0 1 1 1 0 Menin Pex14_N PF04695.8 KEY72762.1 - 1.6 8.8 8.3 2.1 8.4 5.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CorA PF01544.13 KEY72763.1 - 0.0002 20.4 6.8 0.00038 19.5 4.7 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein ATP_bind_3 PF01171.15 KEY72766.1 - 5e-41 140.1 0.0 3.7e-29 101.5 0.0 2.3 2 0 0 2 2 2 2 PP-loop family Asn_synthase PF00733.16 KEY72766.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase SNARE PF05739.14 KEY72767.1 - 0.14 11.8 0.4 15 5.3 0.0 2.4 2 0 0 2 2 2 0 SNARE domain DUF4098 PF13345.1 KEY72768.1 - 1e-05 25.3 15.0 0.07 13.0 0.0 5.7 6 1 0 7 7 7 3 Domain of unknown function (DUF4098) Mito_carr PF00153.22 KEY72769.1 - 5.2e-68 224.8 5.1 1.5e-25 88.6 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 KEY72769.1 - 4.3e-23 81.2 2.2 1.4e-14 53.9 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KEY72769.1 - 1.3e-21 74.1 3.9 1.1e-06 27.4 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.1 KEY72769.1 - 1e-16 59.4 5.6 0.00014 21.0 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KEY72769.1 - 1e-15 56.1 5.4 1.8e-05 24.2 0.2 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KEY72769.1 - 3.4e-14 52.2 2.0 0.00054 19.5 0.1 3.4 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KEY72769.1 - 2.8e-07 30.5 0.0 0.00068 19.6 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 KEY72769.1 - 0.0033 17.0 0.1 2.9 7.6 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.2 KEY72769.1 - 0.013 15.1 1.8 2.9 7.6 0.1 2.8 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Cyclin_N PF00134.18 KEY72770.1 - 1.9e-12 46.8 0.5 9.2e-11 41.4 0.1 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Turandot PF07240.6 KEY72770.1 - 0.059 12.8 0.1 0.18 11.2 0.1 1.8 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot Abhydrolase_6 PF12697.2 KEY72771.1 - 9e-20 71.5 0.6 9e-20 71.5 0.4 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY72771.1 - 1.4e-08 34.5 0.0 2.9e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY72771.1 - 3.2e-07 30.1 0.0 6.8e-07 29.0 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KEY72771.1 - 4.3e-05 23.2 0.0 8.5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 KEY72771.1 - 0.028 14.0 0.0 0.066 12.8 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) DLH PF01738.13 KEY72771.1 - 0.11 11.8 0.0 0.38 10.0 0.0 1.8 2 1 0 2 2 2 0 Dienelactone hydrolase family BAAT_C PF08840.6 KEY72771.1 - 0.13 11.9 0.0 3 7.5 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.15 KEY72771.1 - 0.2 11.8 0.7 0.41 10.8 0.5 1.4 1 0 0 1 1 1 0 Thioesterase domain APH PF01636.18 KEY72772.1 - 5.5e-08 32.8 0.0 9.5e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4452 PF14618.1 KEY72774.1 - 1.3e-69 233.2 13.6 1.5e-69 233.0 9.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Mito_carr PF00153.22 KEY72776.1 - 8.1e-44 147.2 9.2 3e-15 55.6 0.1 3.9 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF3628 PF12300.3 KEY72776.1 - 0.18 11.8 2.3 0.27 11.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3628) DUF3337 PF11816.3 KEY72777.1 - 2.7e-91 306.4 0.0 1.3e-87 294.3 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 KEY72777.1 - 3.5e-27 93.2 4.9 3.3e-05 23.6 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KEY72777.1 - 0.044 11.9 0.2 0.13 10.3 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 KH_1 PF00013.24 KEY72778.1 - 6.9e-43 144.1 13.3 2.1e-16 59.3 1.2 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KEY72778.1 - 8.2e-31 105.1 16.9 2.6e-10 39.6 1.1 4.0 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 KEY72778.1 - 3.8e-12 45.5 2.4 0.0098 15.4 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KEY72778.1 - 2.3e-08 33.5 3.8 0.09 12.4 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KEY72778.1 - 0.00018 21.2 4.4 0.24 11.2 0.0 3.6 4 0 0 4 4 4 2 NusA-like KH domain SLS PF14611.1 KEY72778.1 - 0.21 10.9 0.0 11 5.3 0.0 2.5 3 0 0 3 3 3 0 Mitochondrial inner-membrane-bound regulator Prothymosin PF03247.9 KEY72779.1 - 0.21 11.7 6.9 0.26 11.4 4.8 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF829 PF05705.9 KEY72780.1 - 1.6e-39 136.0 0.0 1.8e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Asp PF00026.18 KEY72781.1 - 3.5e-41 141.4 0.1 5.8e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 KEY72781.1 - 0.00024 20.6 0.1 0.0016 17.9 0.1 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KEY72781.1 - 0.002 18.5 0.1 1.7 9.1 0.0 3.1 3 0 0 3 3 3 2 Aspartyl protease 6PF2K PF01591.13 KEY72782.1 - 1.3e-78 263.0 0.1 1.8e-78 262.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KEY72782.1 - 2.4e-30 105.7 0.0 4.5e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KEY72782.1 - 6.5e-10 39.0 0.1 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KEY72782.1 - 3.8e-05 23.0 0.0 5.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KEY72782.1 - 0.00023 21.9 0.7 0.011 16.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KEY72782.1 - 0.087 11.9 0.0 0.58 9.2 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin DUF1183 PF06682.7 KEY72783.1 - 3.7 7.0 7.9 5.2 6.5 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) AA_permease_2 PF13520.1 KEY72784.1 - 5.6e-05 21.8 0.0 5.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Amino acid permease CBF_beta PF02312.12 KEY72784.1 - 0.0053 16.4 0.0 0.0076 15.8 0.0 1.2 1 0 0 1 1 1 1 Core binding factor beta subunit PetN PF03742.9 KEY72784.1 - 0.23 11.0 1.9 1.2 8.8 0.2 2.3 2 0 0 2 2 2 0 PetN Sterol-sensing PF12349.3 KEY72785.1 - 0.0074 15.7 2.4 0.013 14.9 1.7 1.3 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Ank_2 PF12796.2 KEY72786.1 - 1.9e-112 367.8 51.8 4.8e-19 68.4 2.4 10.1 1 1 11 13 13 13 12 Ankyrin repeats (3 copies) Ank PF00023.25 KEY72786.1 - 1.6e-68 223.3 53.4 1.3e-06 27.8 0.5 19.5 20 0 0 20 20 20 15 Ankyrin repeat Ank_4 PF13637.1 KEY72786.1 - 1.3e-57 191.2 23.8 2.2e-08 34.3 0.0 15.9 8 5 8 17 17 17 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY72786.1 - 2.7e-48 157.1 34.3 7.8e-05 22.5 0.1 19.4 21 0 0 21 21 21 10 Ankyrin repeat Ank_5 PF13857.1 KEY72786.1 - 2.2e-44 148.4 42.0 4.1e-07 30.0 0.9 14.8 6 3 10 16 16 16 13 Ankyrin repeats (many copies) AAA_22 PF13401.1 KEY72786.1 - 0.00027 21.1 0.1 0.0012 18.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain PGAP1 PF07819.8 KEY72786.1 - 0.0021 17.6 0.0 0.022 14.3 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.9 KEY72786.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.10 KEY72786.1 - 0.2 10.6 0.0 0.46 9.4 0.0 1.5 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase NAD_binding_4 PF07993.7 KEY72788.1 - 2.1e-34 118.5 0.0 3.3e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KEY72788.1 - 1.8e-28 99.0 0.0 2.7e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 KEY72788.1 - 9.1e-08 32.2 0.0 2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 KEY72788.1 - 6.8e-06 25.6 0.0 1.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KEY72788.1 - 0.088 12.7 0.1 0.96 9.3 0.1 2.3 1 1 0 1 1 1 0 short chain dehydrogenase PS-DH PF14765.1 KEY72789.1 - 2.6e-47 161.4 0.6 6.6e-47 160.0 0.4 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 KEY72789.1 - 1e-44 152.3 2.2 1.9e-43 148.2 0.0 3.3 4 0 0 4 4 4 1 KR domain Acyl_transf_1 PF00698.16 KEY72789.1 - 2.9e-39 135.2 0.0 8.9e-39 133.6 0.0 1.9 1 1 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KEY72789.1 - 2e-36 124.4 0.1 6.1e-36 122.8 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KEY72789.1 - 6.3e-32 110.7 5.1 1.3e-30 106.5 0.0 3.2 3 0 0 3 3 3 1 short chain dehydrogenase ketoacyl-synt PF00109.21 KEY72789.1 - 1.3e-24 87.1 1.0 3.9e-24 85.4 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain 3Beta_HSD PF01073.14 KEY72789.1 - 0.0015 17.3 0.0 0.0024 16.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 KEY72789.1 - 0.0019 18.4 0.1 0.026 14.7 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.21 KEY72789.1 - 0.024 14.1 0.0 0.25 10.9 0.0 2.7 3 0 0 3 3 3 0 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 KEY72789.1 - 0.029 14.1 0.6 0.088 12.6 0.4 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DNA_gyraseB_C PF00986.16 KEY72789.1 - 0.36 10.6 0.0 20 5.0 0.0 2.7 2 0 0 2 2 2 0 DNA gyrase B subunit, carboxyl terminus GFO_IDH_MocA PF01408.17 KEY72790.1 - 9.1e-16 58.4 0.0 1.3e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ABC2_membrane PF01061.19 KEY72791.1 - 1e-74 250.2 42.4 1.9e-37 128.5 11.5 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 KEY72791.1 - 3e-33 114.9 0.0 2.8e-18 66.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KEY72791.1 - 3.5e-26 90.8 2.2 4.6e-24 84.0 0.0 3.3 3 0 0 3 3 3 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 KEY72791.1 - 8.8e-10 38.1 30.1 5.4e-05 22.3 10.0 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KEY72791.1 - 1.1e-08 34.7 0.9 6.6e-05 22.3 0.3 2.7 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEY72791.1 - 2.7e-05 24.2 0.5 0.0015 18.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KEY72791.1 - 6.2e-05 22.4 0.4 0.014 14.9 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_trans_N PF14510.1 KEY72791.1 - 0.00011 22.1 0.0 0.00028 20.9 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 KEY72791.1 - 0.00023 20.4 0.0 0.0015 17.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 KEY72791.1 - 0.00063 19.4 0.1 0.038 13.7 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 KEY72791.1 - 0.0012 18.5 0.1 0.12 12.0 0.0 2.8 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.14 KEY72791.1 - 0.0017 17.6 0.1 3.9 6.6 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEY72791.1 - 0.0022 18.0 0.0 0.081 12.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KEY72791.1 - 0.003 17.0 0.5 0.85 8.9 0.1 2.9 3 1 1 4 4 4 1 AAA-like domain AAA_33 PF13671.1 KEY72791.1 - 0.0037 17.1 0.1 0.62 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KEY72791.1 - 0.0043 15.9 0.2 0.8 8.5 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Arch_ATPase PF01637.13 KEY72791.1 - 0.0044 16.7 0.0 0.022 14.4 0.0 1.9 2 0 0 2 2 2 1 Archaeal ATPase AAA_23 PF13476.1 KEY72791.1 - 0.0045 17.3 0.1 0.009 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEY72791.1 - 0.0064 16.6 0.1 0.15 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KEY72791.1 - 0.016 14.6 1.4 0.05 13.0 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 KEY72791.1 - 0.019 14.5 0.3 0.17 11.5 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 KEY72791.1 - 0.027 15.2 0.0 0.18 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KEY72791.1 - 0.048 13.9 0.0 0.38 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KEY72791.1 - 0.061 12.7 0.1 0.75 9.2 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.1 KEY72791.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KEY72791.1 - 0.11 12.0 0.0 1 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 KEY72791.1 - 0.18 11.5 0.0 5.2 6.7 0.0 2.9 3 0 0 3 3 3 0 NTPase PduV-EutP PF10662.4 KEY72791.1 - 0.19 11.1 0.4 0.87 9.0 0.1 2.2 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation DDE_1 PF03184.14 KEY72792.1 - 5e-28 97.7 0.0 7.7e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KEY72792.1 - 2.7e-05 23.9 0.0 4.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease ROKNT PF08067.6 KEY72792.1 - 0.37 10.6 2.7 0.78 9.6 1.9 1.4 1 0 0 1 1 1 0 ROKNT (NUC014) domain SnoaL PF07366.7 KEY72793.1 - 8.1e-07 28.6 0.0 8.8e-07 28.5 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KEY72793.1 - 0.00014 22.2 0.0 0.00015 22.0 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain HSP20 PF00011.16 KEY72794.1 - 1.6e-10 40.7 0.2 1.7e-06 27.7 0.0 2.2 1 1 0 2 2 2 2 Hsp20/alpha crystallin family DUF4129 PF13559.1 KEY72794.1 - 0.035 14.0 0.0 0.098 12.6 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4129) DUF3732 PF12532.3 KEY72794.1 - 0.09 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) Peptidase_S10 PF00450.17 KEY72796.1 - 1.9e-80 271.1 0.0 2.9e-80 270.4 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase DUF3129 PF11327.3 KEY72797.1 - 4.3e-51 173.3 13.8 5.2e-51 173.0 9.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Glyco_transf_15 PF01793.11 KEY72799.1 - 1.7e-121 405.2 0.9 2.1e-121 404.9 0.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF953 PF06110.6 KEY72801.1 - 1.2e-17 63.4 0.0 1.3e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.1 KEY72801.1 - 0.00088 18.8 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KEY72801.1 - 0.0047 17.0 0.1 0.0063 16.6 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 KEY72801.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Exo_endo_phos PF03372.18 KEY72802.1 - 7.9e-16 58.7 0.0 9.9e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KEY72802.1 - 4.9e-06 26.1 0.0 1.2e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase 3HCDH_N PF02737.13 KEY72803.1 - 1.3e-26 93.3 0.0 2.1e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KEY72803.1 - 1.9e-22 79.4 0.0 4.5e-22 78.2 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ApbA PF02558.11 KEY72803.1 - 4.9e-05 22.8 0.0 0.00019 20.9 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KEY72803.1 - 0.0047 16.6 0.0 0.0099 15.6 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.19 KEY72803.1 - 0.02 13.7 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_2 PF03446.10 KEY72803.1 - 0.027 14.3 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KEY72803.1 - 0.058 13.8 0.1 0.14 12.6 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_3 PF01494.14 KEY72803.1 - 0.065 12.2 0.0 0.093 11.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 KEY72803.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.22 KEY72803.1 - 0.15 12.5 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 KEY72805.1 - 1.3e-36 126.0 35.1 1.7e-36 125.6 24.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KEY72805.1 - 0.00016 21.3 1.3 0.00067 19.4 0.9 2.2 1 0 0 1 1 1 1 MFS_1 like family DUF4267 PF14087.1 KEY72806.1 - 6.8e-13 48.2 0.7 9.3e-13 47.7 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Glyco_hydro_3 PF00933.16 KEY72807.1 - 2.9e-85 285.8 0.0 4.2e-85 285.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY72807.1 - 2.2e-54 184.3 0.1 3.3e-54 183.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEY72807.1 - 2.8e-24 84.8 0.0 5.1e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Yippee-Mis18 PF03226.9 KEY72809.1 - 1.4e-14 53.8 0.1 1.7e-14 53.6 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 KEY72809.1 - 0.0037 17.1 0.3 0.0049 16.7 0.2 1.3 1 1 0 1 1 1 1 C-terminal domain of RIG-I Endonuclease_7 PF02945.10 KEY72809.1 - 0.037 13.7 1.2 0.095 12.4 0.8 1.8 1 1 0 1 1 1 0 Recombination endonuclease VII Evr1_Alr PF04777.8 KEY72809.1 - 0.063 13.1 0.8 0.44 10.4 0.0 2.0 1 1 1 2 2 2 0 Erv1 / Alr family HECT_2 PF09814.4 KEY72809.1 - 0.14 10.8 0.4 0.31 9.6 0.2 1.7 1 1 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding GFA PF04828.9 KEY72810.1 - 4.5e-09 36.1 0.3 4.5e-09 36.1 0.2 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_2 PF13240.1 KEY72810.1 - 0.053 13.0 0.0 0.053 13.0 0.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain PQ-loop PF04193.9 KEY72811.1 - 1.5e-21 75.7 6.4 1.5e-17 62.9 0.1 3.2 3 0 0 3 3 3 2 PQ loop repeat BPD_transp_2 PF02653.11 KEY72811.1 - 0.0024 16.8 9.6 0.0043 16.0 6.6 1.4 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component DUF1275 PF06912.6 KEY72811.1 - 0.01 15.0 3.8 0.012 14.7 1.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1275) DUF1097 PF06496.6 KEY72811.1 - 0.016 15.0 4.8 1.4 8.6 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1097) Arteri_Gl PF00951.13 KEY72811.1 - 0.053 13.1 3.1 0.034 13.7 0.7 1.7 1 1 1 2 2 2 0 Arterivirus GL envelope glycoprotein DUF3995 PF13160.1 KEY72811.1 - 0.11 12.5 10.5 0.098 12.7 3.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3995) ER_lumen_recept PF00810.13 KEY72811.1 - 0.39 11.1 4.4 1.2 9.6 0.0 2.8 1 1 1 3 3 3 0 ER lumen protein retaining receptor DUF4231 PF14015.1 KEY72811.1 - 0.67 9.9 7.6 0.41 10.6 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Amastin PF07344.6 KEY72811.1 - 0.73 9.4 6.4 0.13 11.8 1.4 1.9 2 0 0 2 2 2 0 Amastin surface glycoprotein Oxidored_q2 PF00420.19 KEY72811.1 - 1.4 8.5 8.0 0.14 11.7 0.7 2.7 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L HlyIII PF03006.15 KEY72811.1 - 3.4 7.0 8.2 5.7 6.2 4.1 2.4 1 1 1 2 2 2 0 Haemolysin-III related Aldose_epim PF01263.15 KEY72813.1 - 1.3e-47 162.3 0.2 1.6e-47 162.1 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DUF3108 PF11306.3 KEY72813.1 - 0.49 10.0 3.9 4.5 6.8 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3108) VWA_3 PF13768.1 KEY72814.1 - 8.9e-29 100.1 0.0 1.8e-28 99.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 KEY72814.1 - 2e-17 62.9 0.0 3.7e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 KEY72814.1 - 7.6e-13 48.9 0.0 1.5e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 KEY72814.1 - 5.7e-08 32.1 0.0 1.9e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 KEY72814.1 - 1.9e-06 27.7 0.0 3.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 KEY72814.1 - 0.0044 16.2 0.0 0.0086 15.2 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein CDC45 PF02724.9 KEY72814.1 - 0.093 10.7 3.3 0.15 10.0 2.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KEY72814.1 - 0.53 8.1 7.4 0.86 7.4 5.1 1.2 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 KEY72814.1 - 0.6 9.6 9.5 1.4 8.4 6.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 KEY72814.1 - 1.3 7.3 7.7 2.1 6.7 5.3 1.2 1 0 0 1 1 1 0 Daxx Family ABC2_membrane PF01061.19 KEY72816.1 - 6.7e-88 293.3 68.7 1.6e-45 154.9 18.4 3.6 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 KEY72816.1 - 3.3e-36 124.6 0.0 6.5e-18 65.3 0.0 2.8 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KEY72816.1 - 6.6e-35 118.8 11.3 6.3e-29 99.6 0.0 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KEY72816.1 - 9.7e-15 54.4 0.2 3.7e-14 52.5 0.1 2.1 1 1 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KEY72816.1 - 5.2e-10 39.0 1.0 1.2e-05 24.8 0.0 2.9 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 KEY72816.1 - 2e-05 24.4 0.9 0.0084 15.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KEY72816.1 - 4.5e-05 23.5 1.0 0.0015 18.5 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 KEY72816.1 - 0.00011 21.4 0.0 0.0037 16.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KEY72816.1 - 0.00013 22.7 0.0 0.21 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEY72816.1 - 0.00023 21.4 0.0 0.056 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEY72816.1 - 0.00037 19.9 1.1 0.04 13.4 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 KEY72816.1 - 0.00078 18.5 22.7 0.00078 18.5 15.7 4.4 3 2 1 4 4 3 1 ABC-2 family transporter protein SMC_N PF02463.14 KEY72816.1 - 0.049 12.8 0.0 1.8 7.7 0.0 2.8 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KEY72816.1 - 0.05 13.7 0.1 0.79 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KEY72816.1 - 0.072 12.8 1.6 12 5.7 0.5 2.7 2 0 0 2 2 2 0 Part of AAA domain Zeta_toxin PF06414.7 KEY72816.1 - 0.11 11.5 0.0 13 4.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.1 KEY72816.1 - 0.12 11.9 0.1 4 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KEY72816.1 - 0.13 12.1 0.0 15 5.5 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase UPF0079 PF02367.12 KEY72816.1 - 0.2 11.3 0.8 1.5 8.5 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KEY72816.1 - 0.21 11.2 2.1 2.8 7.5 0.2 2.6 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.1 KEY72816.1 - 0.24 11.3 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 KEY72816.1 - 0.26 10.7 5.5 0.042 13.2 0.6 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF1049 PF06305.6 KEY72816.1 - 0.64 9.5 9.4 3.8 7.0 0.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) NAD_binding_8 PF13450.1 KEY72817.1 - 5.9e-12 45.4 0.2 1.7e-11 43.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEY72817.1 - 4.4e-09 35.7 0.0 1.1e-07 31.1 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEY72817.1 - 3.1e-06 27.4 0.0 0.081 13.3 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY72817.1 - 1.5e-05 25.1 0.1 0.00017 21.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEY72817.1 - 8.9e-05 21.4 0.1 0.00014 20.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KEY72817.1 - 0.00013 21.9 0.0 0.0032 17.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEY72817.1 - 0.00024 20.9 0.0 0.0027 17.4 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 KEY72817.1 - 0.00024 19.6 0.0 0.021 13.3 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 KEY72817.1 - 0.0016 17.4 0.1 0.0025 16.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Amino_oxidase PF01593.19 KEY72817.1 - 0.0023 17.0 0.0 0.019 14.0 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 KEY72817.1 - 0.0031 16.6 0.0 0.042 12.8 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KEY72817.1 - 0.019 14.0 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Saccharop_dh PF03435.13 KEY72817.1 - 0.036 13.0 0.1 0.059 12.3 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_7 PF13241.1 KEY72817.1 - 0.11 12.8 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 KEY72817.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_28 PF00295.12 KEY72818.1 - 1.1e-37 129.7 5.4 2.1e-37 128.8 3.8 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 O-antigen_lig PF13425.1 KEY72818.1 - 0.13 12.2 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 O-antigen ligase like membrane protein FA_hydroxylase PF04116.8 KEY72819.1 - 3.4e-14 53.2 24.1 1.2e-13 51.4 15.7 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily MFS_1 PF07690.11 KEY72820.1 - 2.4e-37 128.4 18.1 2.6e-36 125.0 10.4 2.2 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF4470 PF14737.1 KEY72821.1 - 6.9e-23 80.2 0.1 2.1e-22 78.7 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) Acetyltransf_1 PF00583.19 KEY72821.1 - 7.8e-12 45.0 0.1 1.5e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family zf-MYND PF01753.13 KEY72821.1 - 8.8e-08 31.8 13.5 1.5e-07 31.1 9.4 1.4 1 0 0 1 1 1 1 MYND finger Acetyltransf_7 PF13508.1 KEY72821.1 - 1e-06 28.7 0.0 2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEY72821.1 - 1.4e-05 25.1 0.0 2.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KEY72821.1 - 0.00011 22.0 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 KEY72821.1 - 0.026 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.1 KEY72821.1 - 0.039 13.8 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 KEY72821.1 - 0.048 12.9 0.1 2.1 7.6 0.0 2.3 2 0 0 2 2 2 0 GNAT acetyltransferase 2 zf-HIT PF04438.11 KEY72821.1 - 0.49 10.0 8.6 1 9.0 5.9 1.5 1 0 0 1 1 1 0 HIT zinc finger Glyco_hydro_67M PF07488.7 KEY72822.1 - 4.6e-151 502.3 0.0 6.1e-151 501.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 KEY72822.1 - 3.5e-94 314.4 1.9 3.5e-94 314.4 1.3 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 KEY72822.1 - 1e-27 96.5 0.0 2.1e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.10 KEY72822.1 - 0.00084 19.8 0.1 0.0037 17.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 ADH_zinc_N PF00107.21 KEY72823.1 - 8.7e-06 25.3 0.1 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY72823.1 - 7e-05 22.5 0.0 0.0002 21.1 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NIR_SIR PF01077.17 KEY72823.1 - 0.04 13.2 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain Zn_clus PF00172.13 KEY72824.1 - 0.0091 15.8 2.3 0.0091 15.8 1.6 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_88 PF07470.8 KEY72825.1 - 7.7e-87 291.4 1.6 8.8e-87 291.2 1.1 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 KEY72825.1 - 0.0036 15.6 0.5 0.0052 15.1 0.3 1.1 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_76 PF03663.9 KEY72825.1 - 0.075 12.3 7.7 0.13 11.6 0.9 2.5 2 1 1 3 3 3 0 Glycosyl hydrolase family 76 MiaE PF06175.6 KEY72825.1 - 0.077 12.3 0.0 0.44 9.8 0.0 1.9 2 0 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) Prenyltrans_2 PF13249.1 KEY72825.1 - 0.079 13.3 0.1 1.2 9.5 0.0 2.5 3 0 0 3 3 3 0 Prenyltransferase-like MFS_1 PF07690.11 KEY72826.1 - 9.1e-33 113.4 14.5 1.4e-32 112.8 10.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY72826.1 - 3.1e-10 39.2 0.6 3.1e-10 39.2 0.4 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.8 KEY72826.1 - 0.00079 17.6 4.8 0.0057 14.8 0.8 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector MFS_2 PF13347.1 KEY72826.1 - 0.00099 17.6 15.5 0.0058 15.0 1.8 3.3 1 1 1 3 3 3 3 MFS/sugar transport protein Folate_carrier PF01770.13 KEY72826.1 - 0.0057 15.2 0.1 0.013 14.0 0.1 1.5 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.11 KEY72827.1 - 6.9e-49 166.4 36.4 6.9e-49 166.4 25.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY72827.1 - 3.9e-16 58.6 15.2 5.4e-16 58.2 10.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 KEY72827.1 - 0.0017 16.5 4.3 0.0017 16.5 3.0 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector Abhydrolase_5 PF12695.2 KEY72828.1 - 0.0022 17.7 0.8 0.0054 16.5 0.5 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY72828.1 - 0.035 13.9 1.2 0.13 12.0 0.8 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family F-box-like PF12937.2 KEY72829.1 - 7.2e-05 22.4 3.2 0.00015 21.4 0.8 2.5 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 KEY72829.1 - 0.0022 17.7 0.8 0.0084 15.8 0.1 2.5 3 1 0 3 3 3 1 F-box-like domain Methyltransf_15 PF09445.5 KEY72829.1 - 0.12 11.9 0.0 1.1 8.8 0.0 2.4 3 0 0 3 3 3 0 RNA cap guanine-N2 methyltransferase DUF4200 PF13863.1 KEY72829.1 - 0.18 11.7 2.5 0.37 10.7 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) 2OG-FeII_Oxy_3 PF13640.1 KEY72832.1 - 9e-10 38.9 0.1 1.8e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KEY72832.1 - 0.018 14.6 0.1 0.042 13.4 0.1 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.8 KEY72832.1 - 0.29 9.8 0.0 0.5 9.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus C4/C10 protein Zot PF05707.7 KEY72833.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF4612 PF15389.1 KEY72834.1 - 0.053 14.1 0.2 0.12 13.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4612) CBM_4_9 PF02018.12 KEY72835.1 - 3.5e-07 30.3 0.1 6.3e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Carbohydrate binding domain Pyr_redox_3 PF13738.1 KEY72836.1 - 5.5e-26 91.9 0.0 4.6e-25 88.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEY72836.1 - 2.8e-07 29.1 0.0 6.6e-07 27.9 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KEY72836.1 - 1.6e-05 23.9 0.0 0.0007 18.6 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KEY72836.1 - 3.1e-05 23.9 0.0 0.48 10.2 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEY72836.1 - 6.4e-05 22.7 0.4 0.045 13.5 0.0 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KEY72836.1 - 0.00021 21.2 0.1 0.0034 17.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KEY72836.1 - 0.0011 19.0 0.0 0.038 14.0 0.0 2.5 3 0 0 3 3 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KEY72836.1 - 0.0012 19.2 0.0 0.1 12.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEY72836.1 - 0.11 11.3 1.9 3.2 6.5 0.1 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 KEY72836.1 - 0.14 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KEY72836.1 - 0.15 12.3 0.0 0.59 10.4 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF4066 PF13278.1 KEY72837.1 - 2.8e-14 52.7 0.0 3.7e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KEY72837.1 - 0.00046 19.6 0.0 0.00064 19.1 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family BTB PF00651.26 KEY72838.1 - 6.9e-11 42.1 0.0 1.4e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Laminin_G_3 PF13385.1 KEY72839.1 - 7.2e-08 32.8 2.3 9.7e-08 32.3 1.6 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Glyco_hydro_16 PF00722.16 KEY72839.1 - 0.00028 20.2 0.2 0.00043 19.6 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Laminin_G_2 PF02210.19 KEY72839.1 - 0.018 15.0 0.1 0.028 14.4 0.1 1.3 1 0 0 1 1 1 0 Laminin G domain Epimerase PF01370.16 KEY72840.1 - 1.6e-15 57.2 0.0 2.2e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEY72840.1 - 1.3e-10 40.4 0.0 2.9e-10 39.3 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KEY72840.1 - 4.6e-08 33.2 0.6 1.3e-07 31.7 0.4 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KEY72840.1 - 4.2e-06 25.8 0.0 7.6e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KEY72840.1 - 0.00045 19.5 0.1 0.00067 18.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KEY72840.1 - 0.0032 17.4 0.9 0.011 15.6 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KEY72840.1 - 0.099 11.5 0.0 0.19 10.5 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Amidase PF01425.16 KEY72842.1 - 4.3e-33 114.8 0.0 7.2e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Amidase FA_desaturase PF00487.19 KEY72843.1 - 6.2e-40 137.2 20.8 1e-39 136.5 14.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KEY72843.1 - 2.1e-09 37.0 0.0 5.4e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Inositol_P PF00459.20 KEY72844.1 - 1.3e-74 250.9 0.0 1.7e-74 250.5 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family Ribonuc_L-PSP PF01042.16 KEY72844.1 - 3e-35 120.5 0.0 5.3e-35 119.7 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP FYVE_2 PF02318.11 KEY72845.1 - 0.0034 17.2 0.1 0.004 17.0 0.1 1.2 1 0 0 1 1 1 1 FYVE-type zinc finger CHORD PF04968.7 KEY72845.1 - 0.08 13.2 0.9 0.08 13.2 0.6 2.6 2 1 0 2 2 2 0 CHORD CpeT PF06206.6 KEY72845.1 - 0.11 12.1 0.1 0.14 11.8 0.1 1.1 1 0 0 1 1 1 0 CpeT/CpcT family (DUF1001) OsmC PF02566.14 KEY72846.1 - 3.2e-19 68.9 0.0 5.4e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein CBM_15 PF03426.9 KEY72846.1 - 0.048 13.0 0.1 0.067 12.5 0.1 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) Cpn10 PF00166.16 KEY72846.1 - 0.064 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Chaperonin 10 Kd subunit Glyco_hydro_3 PF00933.16 KEY72847.1 - 6.4e-90 301.1 0.0 9.2e-90 300.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY72847.1 - 3.6e-52 177.1 0.0 6.4e-51 173.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEY72847.1 - 5.7e-26 90.2 0.4 1e-25 89.4 0.3 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF2648 PF10855.3 KEY72847.1 - 0.21 11.0 0.7 0.49 9.8 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) MbeD_MobD PF04899.7 KEY72849.1 - 0.0043 16.9 1.1 0.094 12.6 0.2 2.9 2 0 0 2 2 2 1 MbeD/MobD like AF-4 PF05110.8 KEY72851.1 - 0.0042 15.0 0.2 0.0049 14.8 0.1 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein UPF0181 PF03701.9 KEY72851.1 - 0.18 11.1 0.6 1 8.7 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) CorA PF01544.13 KEY72852.1 - 4.8e-07 29.1 0.1 7.4e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Ribosomal_S14 PF00253.16 KEY72854.1 - 4.6e-18 64.3 0.7 8.1e-18 63.5 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e CWC25 PF12542.3 KEY72855.1 - 3.9e-27 94.5 2.3 3.9e-27 94.5 1.6 4.4 4 1 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 KEY72855.1 - 2.1e-12 46.8 1.7 2.1e-12 46.8 1.2 4.2 6 0 0 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF3674 PF12426.3 KEY72855.1 - 5.7 6.4 5.6 0.45 9.9 0.1 2.0 2 0 0 2 2 2 0 RNA dependent RNA polymerase Aldedh PF00171.17 KEY72856.1 - 1.5e-132 442.2 0.1 1.7e-132 442.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KEY72856.1 - 0.17 10.6 0.1 0.33 9.6 0.1 1.4 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Yae1_N PF09811.4 KEY72857.1 - 0.13 11.7 0.6 0.23 11.0 0.4 1.4 1 0 0 1 1 1 0 Essential protein Yae1, N terminal TPP_enzyme_N PF02776.13 KEY72858.1 - 1e-40 139.0 1.9 9.7e-37 126.0 1.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KEY72858.1 - 1.3e-17 63.8 0.0 2.6e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KEY72858.1 - 1.3e-17 63.7 0.1 2.7e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain FAD_binding_3 PF01494.14 KEY72859.1 - 8.8e-20 71.0 0.3 4.3e-11 42.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KEY72859.1 - 2.1e-09 36.7 2.5 0.0002 20.3 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEY72859.1 - 3.3e-06 26.2 0.0 5.6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KEY72859.1 - 6.5e-06 26.0 1.1 3.5e-05 23.7 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEY72859.1 - 1.8e-05 23.8 0.6 3.5e-05 22.8 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KEY72859.1 - 0.0006 19.7 0.3 0.001 18.9 0.2 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEY72859.1 - 0.0037 15.8 0.6 0.045 12.2 0.6 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 KEY72859.1 - 0.0038 17.3 0.1 0.0061 16.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEY72859.1 - 0.004 16.2 1.0 0.0084 15.2 0.3 1.7 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 KEY72859.1 - 0.0094 14.8 0.1 0.012 14.4 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KEY72859.1 - 0.01 16.2 0.1 0.06 13.7 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KEY72859.1 - 0.012 14.2 0.0 0.023 13.3 0.0 1.5 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KEY72859.1 - 0.11 12.2 0.3 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 KEY72859.1 - 0.11 12.0 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.11 KEY72861.1 - 1.7e-36 125.6 31.6 2.5e-36 125.1 21.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KEY72862.1 - 8.3e-20 70.7 0.0 1.5e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY72862.1 - 0.054 13.4 14.7 0.096 12.6 10.2 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 KEY72863.1 - 3.1e-31 109.0 2.4 3.7e-31 108.7 1.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY72863.1 - 1.8e-15 57.1 0.6 6.2e-14 52.1 0.4 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY72863.1 - 9.3e-13 48.1 0.4 1.5e-12 47.5 0.3 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KEY72863.1 - 2.4e-08 33.6 0.0 5.2e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 KEY72863.1 - 2.6e-06 26.1 0.0 3.1e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.6 KEY72863.1 - 0.043 13.5 0.0 8.2 6.0 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF4360 PF14273.1 KEY72864.1 - 1.8e-68 229.7 3.3 2.1e-68 229.6 2.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Glyco_hydro_16 PF00722.16 KEY72865.1 - 4.4e-37 127.1 0.3 7.3e-37 126.4 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 T2SM PF04612.7 KEY72865.1 - 0.055 13.2 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M CAF-1_p150 PF11600.3 KEY72866.1 - 0.00039 19.8 5.6 0.00061 19.2 3.9 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal ATP-synt_B PF00430.13 KEY72866.1 - 0.14 11.9 5.5 0.19 11.5 3.8 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Ras PF00071.17 KEY72867.1 - 9.4e-50 168.1 0.0 1.9e-25 89.1 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KEY72867.1 - 6.2e-13 49.2 0.0 1e-11 45.3 0.0 2.1 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEY72867.1 - 0.00012 21.3 0.0 0.00059 19.1 0.0 2.0 2 1 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEY72867.1 - 0.0029 16.7 0.0 0.0044 16.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KEY72867.1 - 0.019 13.6 0.0 0.019 13.6 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit MMR_HSR1 PF01926.18 KEY72867.1 - 0.04 13.8 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 KEY72867.1 - 0.091 13.0 0.0 0.3 11.3 0.0 1.6 1 1 1 2 2 2 0 ABC transporter SRPRB PF09439.5 KEY72867.1 - 0.094 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit HATPase_c PF02518.21 KEY72868.1 - 1.1e-18 66.9 0.0 2.3e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KEY72868.1 - 2.8e-18 65.9 0.0 8.3e-18 64.4 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KEY72868.1 - 1.8e-09 37.4 0.1 4.4e-09 36.1 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Citrate_synt PF00285.16 KEY72869.1 - 1.8e-100 336.1 0.0 2.1e-100 335.9 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase ICL PF00463.16 KEY72870.1 - 1.5e-197 656.9 0.1 1.8e-197 656.6 0.0 1.1 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KEY72870.1 - 1.6e-11 43.8 0.0 2.9e-10 39.7 0.0 2.2 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Abhydrolase_1 PF00561.15 KEY72871.1 - 1.7e-17 63.7 0.0 4.9e-17 62.2 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEY72871.1 - 2e-10 40.9 1.5 8.8e-10 38.8 1.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KEY72871.1 - 0.0025 17.2 0.0 0.0043 16.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 KEY72871.1 - 0.035 13.5 0.3 0.12 11.8 0.1 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase NUDIX PF00293.23 KEY72873.1 - 9.2e-07 28.5 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 KEY72874.1 - 6.5e-19 67.9 0.2 1.5e-18 66.7 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain MFS_1 PF07690.11 KEY72875.1 - 4.1e-19 68.5 30.2 4.1e-19 68.5 21.0 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily PCI PF01399.22 KEY72876.1 - 1.8e-17 63.5 0.4 5.7e-17 61.9 0.0 2.1 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 KEY72876.1 - 1.8e-05 24.5 0.2 3.7e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_10 PF13374.1 KEY72876.1 - 0.038 13.9 0.5 1.4 8.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEY72876.1 - 0.04 13.7 2.5 1.8 8.5 0.1 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEY72876.1 - 0.047 13.6 3.6 0.18 11.7 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4404 PF14357.1 KEY72876.1 - 0.052 13.9 0.0 2.9 8.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) TPR_16 PF13432.1 KEY72876.1 - 0.055 14.1 0.8 0.29 11.8 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Trp_syntA PF00290.15 KEY72876.1 - 0.071 11.6 0.1 0.13 10.7 0.1 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain TPR_12 PF13424.1 KEY72876.1 - 0.099 12.5 5.0 0.55 10.2 0.6 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEY72876.1 - 0.19 11.4 3.4 0.83 9.3 0.5 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEY72876.1 - 0.53 10.8 5.7 0.58 10.7 0.3 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat Zn_clus PF00172.13 KEY72877.1 - 1.6e-05 24.6 9.9 2.9e-05 23.8 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_ligase_A_M PF01068.16 KEY72879.1 - 6.1e-10 38.8 0.0 0.00014 21.3 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KEY72879.1 - 1.7e-06 27.9 0.0 5.6e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 DNA ligase N terminus TolA PF06519.6 KEY72879.1 - 0.03 14.2 0.2 0.092 12.7 0.1 1.8 2 0 0 2 2 2 0 TolA C-terminal Antimicrobial_2 PF08023.7 KEY72879.1 - 0.05 13.9 1.8 0.12 12.6 1.2 1.7 1 0 0 1 1 1 0 Frog antimicrobial peptide Methyltransf_23 PF13489.1 KEY72880.1 - 1.9e-17 63.4 0.0 3.1e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY72880.1 - 8e-10 39.2 0.0 1.4e-08 35.3 0.0 2.4 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY72880.1 - 1.8e-08 34.7 0.0 1.9e-07 31.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY72880.1 - 1.5e-07 31.8 0.0 8.6e-07 29.3 0.0 2.3 3 1 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY72880.1 - 8.6e-07 28.6 0.0 5.5e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY72880.1 - 7.2e-05 23.0 0.0 0.00033 20.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY72880.1 - 0.0027 17.7 0.0 0.012 15.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEY72880.1 - 0.005 15.8 0.0 0.0091 15.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.4 KEY72880.1 - 0.0074 15.7 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 KEY72880.1 - 0.021 14.8 0.2 0.047 13.6 0.1 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.7 KEY72880.1 - 0.024 14.1 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MTS PF05175.9 KEY72880.1 - 0.024 13.9 0.0 0.081 12.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_2 PF00891.13 KEY72880.1 - 0.028 13.5 0.1 2.8 7.0 0.0 2.5 3 0 0 3 3 3 0 O-methyltransferase Ubie_methyltran PF01209.13 KEY72880.1 - 0.032 13.3 0.0 0.22 10.6 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PrmA PF06325.8 KEY72880.1 - 0.12 11.4 0.0 0.26 10.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Clr5 PF14420.1 KEY72883.1 - 4.6e-12 45.6 0.1 8.1e-12 44.8 0.1 1.4 1 0 0 1 1 1 1 Clr5 domain DivIVA PF05103.8 KEY72884.1 - 0.021 14.8 0.6 0.026 14.5 0.4 1.1 1 0 0 1 1 1 0 DivIVA protein CoatB PF10389.4 KEY72884.1 - 0.079 12.8 0.6 0.15 11.9 0.4 1.4 1 0 0 1 1 1 0 Bacteriophage coat protein B Rep_fac-A_3 PF08661.6 KEY72886.1 - 0.015 15.2 0.4 0.067 13.0 0.1 2.0 1 1 1 2 2 2 0 Replication factor A protein 3 Laminin_I PF06008.9 KEY72886.1 - 0.026 13.8 1.1 0.054 12.8 0.8 1.6 1 1 0 1 1 1 0 Laminin Domain I V_ATPase_I PF01496.14 KEY72886.1 - 0.035 11.9 0.3 0.038 11.8 0.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mt_ATP-synt_B PF05405.9 KEY72886.1 - 0.056 12.8 0.4 0.08 12.4 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) LPP20 PF02169.11 KEY72886.1 - 0.096 12.7 0.9 0.13 12.4 0.6 1.3 1 0 0 1 1 1 0 LPP20 lipoprotein Orthopox_A5L PF06193.6 KEY72886.1 - 0.11 12.3 1.6 2.1 8.2 0.3 2.2 1 1 1 2 2 2 0 Orthopoxvirus A5L protein-like DUF4164 PF13747.1 KEY72886.1 - 0.12 12.4 1.2 0.22 11.6 0.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) LOH1CR12 PF10158.4 KEY72887.1 - 0.07 12.9 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Tumour suppressor protein IL2 PF00715.12 KEY72887.1 - 0.11 12.2 0.2 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Interleukin 2 NAD_binding_1 PF00175.16 KEY72888.1 - 0.0013 19.3 0.0 0.86 10.1 0.0 2.5 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KEY72888.1 - 0.0015 18.4 0.0 0.0032 17.4 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain ERM PF00769.14 KEY72889.1 - 0.045 13.2 14.3 0.014 14.9 6.9 1.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HlyD PF00529.15 KEY72889.1 - 0.23 10.7 7.9 0.29 10.4 5.5 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DUF724 PF05266.9 KEY72889.1 - 0.29 10.7 4.2 0.44 10.1 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF501 PF04417.7 KEY72889.1 - 0.58 10.0 3.3 0.53 10.1 0.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF501) APG6 PF04111.7 KEY72889.1 - 2.5 7.0 9.0 3 6.8 6.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4407 PF14362.1 KEY72889.1 - 7.2 5.4 9.8 9.9 5.0 6.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) IncA PF04156.9 KEY72889.1 - 9.7 5.7 12.1 13 5.3 8.4 1.3 1 0 0 1 1 1 0 IncA protein Fungal_trans PF04082.13 KEY72890.1 - 5.7e-08 31.9 0.8 1e-07 31.1 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY72890.1 - 0.0072 16.2 0.8 0.018 14.9 0.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3435 PF11917.3 KEY72891.1 - 1.7e-26 92.9 2.1 2.3e-26 92.5 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) APH PF01636.18 KEY72893.1 - 8e-17 61.7 0.0 1e-16 61.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEY72893.1 - 0.0025 17.4 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KEY72893.1 - 0.0035 16.7 0.0 0.037 13.3 0.0 2.0 2 0 0 2 2 2 1 RIO1 family SBP_bac_3 PF00497.15 KEY72893.1 - 0.043 13.0 0.0 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 HlyIII PF03006.15 KEY72895.1 - 1.3e-25 90.1 3.3 1.4e-25 90.0 2.3 1.0 1 0 0 1 1 1 1 Haemolysin-III related Kelch_5 PF13854.1 KEY72896.1 - 1.9e-09 37.2 0.7 1.8e-08 34.1 0.1 2.9 3 0 0 3 3 3 1 Kelch motif CD99L2 PF12301.3 KEY72896.1 - 0.043 13.5 0.2 0.066 12.8 0.1 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 SKG6 PF08693.5 KEY72896.1 - 0.061 12.6 0.3 0.13 11.5 0.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Phage_HK97_TLTM PF06120.6 KEY72896.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Tail length tape measure protein Herpes_gE PF02480.11 KEY72896.1 - 0.15 10.3 0.0 0.21 9.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Kelch_6 PF13964.1 KEY72896.1 - 1.8 8.9 8.6 8.7 6.7 0.7 4.9 5 1 0 5 5 5 0 Kelch motif HET PF06985.6 KEY72897.1 - 0.13 12.4 0.3 0.42 10.7 0.2 1.8 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) MUG113 PF13455.1 KEY72898.1 - 3.6e-29 101.0 0.1 7.9e-29 99.9 0.0 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 KEY72898.1 - 5.3e-22 78.0 0.0 1.3e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain DUF4551 PF15087.1 KEY72898.1 - 6.1 5.0 10.2 12 4.1 7.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4551) Sod_Fe_C PF02777.13 KEY72900.1 - 2.6e-34 117.2 1.3 3.3e-34 116.8 0.2 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KEY72900.1 - 1.3e-33 115.0 3.3 1.6e-33 114.8 0.8 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF89 PF01937.14 KEY72903.1 - 3.2e-126 420.8 0.0 3.7e-126 420.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 F-box PF00646.28 KEY72904.1 - 0.0038 16.8 0.3 0.0097 15.5 0.1 1.7 2 0 0 2 2 2 1 F-box domain GAS PF13851.1 KEY72905.1 - 7.3 5.7 26.1 0.72 9.0 4.7 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Complex1_LYR PF05347.10 KEY72907.1 - 3.2e-06 26.8 0.1 4e-06 26.5 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 KEY72907.1 - 4e-06 27.2 0.0 4.5e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 KEY72907.1 - 4.3e-05 23.6 0.1 5.1e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Methyltransf_25 PF13649.1 KEY72908.1 - 4.2e-10 39.9 0.0 7.3e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY72908.1 - 7e-09 36.2 0.0 1.3e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY72908.1 - 2e-08 34.1 0.0 3.5e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY72908.1 - 9.9e-08 32.0 0.0 2.5e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY72908.1 - 7e-07 29.6 0.0 1.2e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY72908.1 - 1.1e-06 28.9 0.0 2.1e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY72908.1 - 0.00046 19.8 0.0 0.00086 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KEY72908.1 - 0.0065 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY72908.1 - 0.035 13.4 0.0 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_24 PF13578.1 KEY72908.1 - 0.086 13.6 0.0 0.19 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 KEY72908.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Exo_endo_phos PF03372.18 KEY72909.1 - 3.4e-22 79.5 0.1 5.6e-22 78.8 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 KEY72909.1 - 5.9e-15 54.4 4.6 6.2e-08 32.0 0.0 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEY72909.1 - 4e-07 29.1 3.9 0.037 14.0 0.0 4.7 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_8 PF13855.1 KEY72909.1 - 2.5e-06 27.1 5.3 0.0001 21.9 0.1 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 KEY72909.1 - 0.00022 20.9 0.8 9.4 6.9 0.0 4.1 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.1 KEY72909.1 - 0.011 15.6 0.2 3.7 7.8 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich repeat Herpes_LMP2 PF07415.6 KEY72909.1 - 0.23 9.9 1.5 0.35 9.3 1.1 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Mito_carr PF00153.22 KEY72910.1 - 1.4e-17 63.2 0.5 1.5e-11 43.8 0.0 3.4 3 1 0 3 3 3 2 Mitochondrial carrier protein Radical_SAM PF04055.16 KEY72911.1 - 4.7e-16 59.4 0.0 1.6e-15 57.7 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 KEY72911.1 - 3.5e-11 42.9 0.0 9e-11 41.6 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ligase_CoA PF00549.14 KEY72912.1 - 4e-24 84.9 0.6 7.2e-24 84.1 0.4 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 KEY72912.1 - 3.3e-21 75.5 9.0 2.1e-20 73.0 2.5 3.1 2 1 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 KEY72912.1 - 1.3e-09 37.7 0.1 2.4e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KEY72912.1 - 0.0023 18.0 0.1 0.0068 16.5 0.0 1.9 1 0 0 1 1 1 1 CoA binding domain UQ_con PF00179.21 KEY72913.1 - 3.6e-38 130.1 0.0 4.5e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 KEY72913.1 - 4.7e-05 22.8 0.1 9.3e-05 21.9 0.1 1.5 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 KEY72913.1 - 0.00043 20.0 0.0 0.00067 19.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KEY72913.1 - 0.1 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 KEY72913.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain AAA PF00004.24 KEY72914.1 - 1.6e-41 141.5 0.0 3e-41 140.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEY72914.1 - 1.1e-06 28.7 0.1 0.00033 20.8 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KEY72914.1 - 3.8e-06 26.9 0.0 7.7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KEY72914.1 - 1.3e-05 24.3 0.0 2.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KEY72914.1 - 3.5e-05 23.5 0.1 0.00014 21.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEY72914.1 - 0.00034 20.6 0.1 0.0014 18.6 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KEY72914.1 - 0.00048 19.2 0.0 0.00089 18.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KEY72914.1 - 0.0013 18.6 0.2 0.0048 16.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KEY72914.1 - 0.0041 17.0 0.0 0.0077 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEY72914.1 - 0.0056 17.5 0.7 0.013 16.3 0.1 2.0 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KEY72914.1 - 0.0065 16.1 0.3 0.016 14.9 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KEY72914.1 - 0.0068 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KEY72914.1 - 0.0091 14.7 0.2 0.042 12.5 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus AAA_33 PF13671.1 KEY72914.1 - 0.0098 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEY72914.1 - 0.01 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.6 KEY72914.1 - 0.011 15.3 0.0 0.027 14.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KEY72914.1 - 0.013 15.7 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KEY72914.1 - 0.017 14.8 0.2 0.33 10.5 0.0 2.5 2 1 1 3 3 3 0 NACHT domain NB-ARC PF00931.17 KEY72914.1 - 0.04 12.7 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.11 KEY72914.1 - 0.045 12.9 3.5 0.21 10.8 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.17 KEY72914.1 - 0.046 13.8 0.0 0.087 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 KEY72914.1 - 0.049 13.2 0.2 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KEY72914.1 - 0.054 12.6 0.1 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KEY72914.1 - 0.076 12.1 0.1 0.41 9.7 0.0 2.0 1 1 0 2 2 2 0 KaiC DUF2075 PF09848.4 KEY72914.1 - 0.14 11.0 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 KEY72914.1 - 0.16 11.3 4.6 0.24 10.7 0.3 2.6 2 1 1 3 3 3 0 AAA domain DUF3329 PF11808.3 KEY72915.1 - 6.1 6.9 15.2 0.067 13.2 2.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3329) PAP2 PF01569.16 KEY72916.1 - 3.7e-19 68.6 6.6 6.3e-19 67.9 4.6 1.4 1 0 0 1 1 1 1 PAP2 superfamily Dimerisation PF08100.6 KEY72917.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain Glyco_hydro_72 PF03198.9 KEY72918.1 - 7.6e-115 383.2 0.1 1e-114 382.8 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KEY72918.1 - 4.9e-21 75.0 2.9 1.3e-20 73.6 2.0 1.7 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 KEY72918.1 - 0.0004 19.6 0.5 0.00094 18.4 0.3 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 KEY72918.1 - 0.0009 18.2 0.0 0.0021 17.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Pkinase PF00069.20 KEY72919.1 - 0.0063 15.6 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ABC_tran PF00005.22 KEY72921.1 - 7.1e-48 162.3 0.0 8.7e-23 81.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KEY72921.1 - 3.9e-20 72.9 1.0 6e-05 23.1 0.0 4.3 3 1 0 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 KEY72921.1 - 1.6e-19 69.4 2.3 1.6e-19 69.4 1.6 2.5 4 0 0 4 4 1 1 ABC transporter SMC_N PF02463.14 KEY72921.1 - 2.4e-11 43.3 0.7 0.0014 17.9 0.1 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KEY72921.1 - 1.4e-09 37.3 0.1 0.0009 18.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KEY72921.1 - 4.4e-08 33.6 3.3 0.027 14.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KEY72921.1 - 1.6e-07 32.2 0.1 0.0015 19.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KEY72921.1 - 1.6e-06 28.3 0.1 0.058 13.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 KEY72921.1 - 3.3e-06 26.3 0.0 0.0046 16.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 KEY72921.1 - 3.8e-06 27.2 0.0 0.061 13.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KEY72921.1 - 1.3e-05 25.1 0.0 0.12 12.3 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 KEY72921.1 - 2.1e-05 24.9 0.0 0.049 14.1 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_28 PF13521.1 KEY72921.1 - 2.2e-05 24.5 0.1 0.015 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KEY72921.1 - 2.6e-05 24.4 0.0 0.19 11.9 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KEY72921.1 - 2.8e-05 23.8 0.3 0.15 11.6 0.0 2.8 3 0 0 3 3 3 2 NACHT domain AAA_16 PF13191.1 KEY72921.1 - 5e-05 23.3 2.2 0.23 11.4 0.1 2.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 KEY72921.1 - 7.7e-05 22.1 0.0 0.16 11.3 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.9 KEY72921.1 - 0.0001 22.0 0.1 0.43 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KEY72921.1 - 0.00013 21.8 0.0 0.42 10.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KEY72921.1 - 0.0003 19.9 0.0 0.18 10.7 0.0 3.1 4 1 0 4 4 2 1 AAA ATPase domain RNA_helicase PF00910.17 KEY72921.1 - 0.0004 20.5 0.9 1.5 9.0 0.0 3.2 3 0 0 3 3 3 2 RNA helicase AAA_10 PF12846.2 KEY72921.1 - 0.00044 19.7 1.1 0.44 9.9 0.2 2.8 3 0 0 3 3 2 2 AAA-like domain AAA_14 PF13173.1 KEY72921.1 - 0.00055 19.8 0.0 1.7 8.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 KEY72921.1 - 0.00067 19.4 0.2 0.36 10.4 0.0 2.8 3 0 0 3 3 2 1 Archaeal ATPase MobB PF03205.9 KEY72921.1 - 0.001 18.7 0.1 0.051 13.2 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 KEY72921.1 - 0.0019 18.0 0.5 0.49 10.3 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 KEY72921.1 - 0.0021 17.9 0.1 2 8.2 0.0 3.3 3 0 0 3 3 3 1 Dynamin family NB-ARC PF00931.17 KEY72921.1 - 0.0029 16.5 0.0 0.56 9.0 0.0 3.0 2 1 0 2 2 2 1 NB-ARC domain MCM PF00493.18 KEY72921.1 - 0.003 16.4 1.8 0.2 10.4 0.0 2.7 3 0 0 3 3 3 1 MCM2/3/5 family DAP3 PF10236.4 KEY72921.1 - 0.012 14.5 0.4 2.1 7.1 0.1 2.7 2 1 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF2813 PF11398.3 KEY72921.1 - 0.016 14.3 0.7 3.1 6.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) ABC_ATPase PF09818.4 KEY72921.1 - 0.023 13.2 0.0 10 4.5 0.0 3.2 3 0 0 3 3 3 0 Predicted ATPase of the ABC class NTPase_1 PF03266.10 KEY72921.1 - 0.035 13.8 0.3 4.8 6.8 0.2 2.6 2 0 0 2 2 2 0 NTPase DUF815 PF05673.8 KEY72921.1 - 0.038 12.9 0.1 1.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 KEY72921.1 - 0.039 13.4 0.0 0.46 9.9 0.0 2.5 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 KEY72921.1 - 0.085 12.3 0.6 6.8 6.1 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 KEY72921.1 - 0.11 12.3 1.1 23 4.7 0.0 3.2 4 0 0 4 4 2 0 Domain of unknown function DUF87 FeoB_N PF02421.13 KEY72921.1 - 0.12 11.6 0.1 8.6 5.6 0.0 2.7 3 0 0 3 3 2 0 Ferrous iron transport protein B ArgK PF03308.11 KEY72921.1 - 0.14 10.9 0.7 13 4.4 0.1 2.6 3 0 0 3 3 3 0 ArgK protein AAA_13 PF13166.1 KEY72921.1 - 0.4 9.0 3.8 15 3.9 0.0 3.4 3 1 0 3 3 3 0 AAA domain DUF3405 PF11885.3 KEY72922.1 - 3e-127 424.9 1.9 3.7e-127 424.5 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) SNF2_N PF00176.18 KEY72923.1 - 5.5e-71 238.8 1.4 1.1e-70 237.7 1.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 KEY72923.1 - 1.4e-50 171.0 17.6 1.4e-50 171.0 12.2 5.4 5 2 1 6 6 6 1 DNA-binding domain Helicase_C PF00271.26 KEY72923.1 - 5e-16 58.3 0.0 1.1e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C2H2_6 PF13912.1 KEY72924.1 - 0.0075 16.1 0.1 0.017 14.9 0.1 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY72924.1 - 0.39 11.1 0.0 0.39 11.1 0.0 3.6 5 0 0 5 5 5 0 Zinc finger, C2H2 type MatE PF01554.13 KEY72925.1 - 4.5e-08 32.8 17.3 4.9e-05 23.0 0.5 3.6 3 0 0 3 3 3 3 MatE TrkH PF02386.11 KEY72927.1 - 4.6e-105 351.0 6.1 4.6e-105 351.0 4.2 2.1 2 0 0 2 2 2 2 Cation transport protein Spore_coat_CotO PF14153.1 KEY72930.1 - 0.029 13.8 7.0 0.041 13.3 4.8 1.3 1 0 0 1 1 1 0 Spore coat protein CotO RRN3 PF05327.6 KEY72930.1 - 0.034 12.2 1.2 0.047 11.7 0.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 APG6 PF04111.7 KEY72930.1 - 0.091 11.7 7.1 0.13 11.2 4.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1777 PF08648.7 KEY72930.1 - 0.2 11.4 17.5 0.34 10.6 12.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Ycf1 PF05758.7 KEY72930.1 - 0.24 9.0 4.2 0.27 8.9 2.9 1.1 1 0 0 1 1 1 0 Ycf1 CALCOCO1 PF07888.6 KEY72930.1 - 0.26 9.5 11.2 0.37 9.0 7.8 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ACCA PF03255.9 KEY72930.1 - 0.55 9.7 6.3 0.96 8.9 4.3 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2361 PF10153.4 KEY72930.1 - 0.86 9.8 12.2 1.7 8.8 8.4 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) DUF2058 PF09831.4 KEY72930.1 - 1.5 8.7 12.5 2.5 7.9 8.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) GOLD_2 PF13897.1 KEY72930.1 - 2 8.6 5.1 18 5.5 0.0 2.4 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking CPSF100_C PF13299.1 KEY72930.1 - 2 8.5 6.6 3.5 7.7 4.6 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Borrelia_P83 PF05262.6 KEY72930.1 - 2.3 6.4 12.7 3.1 5.9 8.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1510 PF07423.6 KEY72930.1 - 2.5 7.4 10.7 4 6.7 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BTV_NS2 PF04514.7 KEY72930.1 - 2.6 6.8 11.6 4.2 6.1 8.1 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 GBP_C PF02841.9 KEY72930.1 - 3.1 6.8 19.9 5.9 5.9 13.8 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Atrophin-1 PF03154.10 KEY72930.1 - 5.1 5.1 22.0 9.1 4.2 15.3 1.3 1 0 0 1 1 1 0 Atrophin-1 family Merozoite_SPAM PF07133.6 KEY72930.1 - 5.2 6.9 14.3 9.1 6.1 9.9 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Mnd1 PF03962.10 KEY72930.1 - 5.5 6.6 20.3 9.1 5.8 14.1 1.2 1 0 0 1 1 1 0 Mnd1 family Radial_spoke_3 PF06098.6 KEY72930.1 - 8.6 5.2 20.1 16 4.3 14.0 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 DUF148 PF02520.12 KEY72932.1 - 0.081 12.7 0.0 0.098 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF148 TPR_10 PF13374.1 KEY72933.1 - 1.1e-18 66.5 0.1 1.1e-09 37.9 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEY72933.1 - 3.9e-13 49.1 0.0 2.1e-08 33.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat NB-ARC PF00931.17 KEY72933.1 - 8.5e-13 47.8 0.0 1.7e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain PNP_UDP_1 PF01048.15 KEY72933.1 - 1.9e-08 33.5 0.1 9.5e-08 31.2 0.1 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_7 PF13176.1 KEY72933.1 - 5.5e-05 22.6 1.5 0.019 14.7 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat NACHT PF05729.7 KEY72933.1 - 0.00052 19.7 0.0 0.0019 17.8 0.0 2.0 2 0 0 2 2 2 1 NACHT domain TPR_11 PF13414.1 KEY72933.1 - 0.0009 18.8 0.1 0.047 13.3 0.0 3.4 4 0 0 4 4 4 1 TPR repeat TPR_17 PF13431.1 KEY72933.1 - 0.0016 18.4 0.0 0.45 10.8 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEY72933.1 - 0.02 15.5 0.3 57 4.7 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEY72933.1 - 0.031 14.2 0.0 6.7 6.8 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat MFS_1 PF07690.11 KEY72934.1 - 5.1e-24 84.6 60.0 4.1e-21 75.0 31.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.14 KEY72935.1 - 3.4e-19 69.1 2.9 3.1e-14 52.8 0.0 2.6 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KEY72935.1 - 1.7e-07 30.4 0.5 1.7e-07 30.4 0.3 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEY72935.1 - 5.1e-05 23.5 1.4 0.00053 20.3 1.1 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY72935.1 - 7.9e-05 22.6 0.2 0.00019 21.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEY72935.1 - 0.0003 19.7 0.0 0.00047 19.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KEY72935.1 - 0.00051 19.2 0.1 0.00082 18.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family SE PF08491.5 KEY72935.1 - 0.00099 18.0 0.0 0.19 10.5 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase NAD_binding_9 PF13454.1 KEY72935.1 - 0.0051 16.6 0.1 0.012 15.4 0.1 1.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KEY72935.1 - 0.008 16.0 0.1 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY72935.1 - 0.029 13.2 0.0 0.059 12.2 0.0 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 KEY72935.1 - 0.072 11.5 0.8 0.11 10.9 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein Epimerase PF01370.16 KEY72936.1 - 1.1e-14 54.4 0.0 1.6e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEY72936.1 - 9.5e-09 34.3 0.0 1.3e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KEY72936.1 - 1.8e-08 33.6 0.0 2.5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 KEY72936.1 - 0.074 11.9 0.0 0.097 11.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain ELMO_CED12 PF04727.8 KEY72936.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 ELMO/CED-12 family FSH1 PF03959.8 KEY72937.1 - 9.3e-31 106.9 0.0 1.2e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KEY72937.1 - 0.0009 19.0 0.1 0.0016 18.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family BBS1 PF14779.1 KEY72937.1 - 0.0028 16.6 0.0 0.0058 15.6 0.0 1.4 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 1 Abhydrolase_6 PF12697.2 KEY72937.1 - 0.0051 16.7 2.1 0.075 12.9 1.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family NAD_binding_8 PF13450.1 KEY72938.1 - 7.1e-12 45.1 0.0 4.7e-11 42.5 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KEY72938.1 - 4.4e-07 29.3 0.2 6.5e-07 28.7 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEY72938.1 - 1.2e-06 27.6 1.4 1.8e-06 27.1 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KEY72938.1 - 2.5e-06 26.2 1.5 3.6e-06 25.7 1.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.19 KEY72938.1 - 2.5e-05 23.5 0.0 6.1e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 KEY72938.1 - 4.3e-05 22.5 0.8 6.7e-05 21.9 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KEY72938.1 - 0.00013 21.1 0.4 0.00019 20.6 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KEY72938.1 - 0.00017 21.9 0.3 0.00037 20.8 0.0 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY72938.1 - 0.0014 18.6 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEY72938.1 - 0.0017 18.2 0.2 0.003 17.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEY72938.1 - 0.0026 16.9 0.2 0.004 16.2 0.1 1.2 1 0 0 1 1 1 1 Thi4 family IlvN PF07991.7 KEY72938.1 - 0.0038 16.6 0.4 0.0075 15.6 0.1 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain GIDA PF01134.17 KEY72938.1 - 0.0074 15.1 0.6 0.011 14.6 0.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A PA14_2 PF10528.4 KEY72938.1 - 0.021 14.7 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 GLEYA domain Lycopene_cycl PF05834.7 KEY72938.1 - 0.025 13.5 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 KEY72938.1 - 0.32 9.5 0.8 0.45 9.0 0.6 1.2 1 0 0 1 1 1 0 Tryptophan halogenase ApbA PF02558.11 KEY72938.1 - 0.62 9.5 2.4 0.56 9.6 0.5 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF3632 PF12311.3 KEY72940.1 - 4.5e-22 78.7 2.7 5.8e-22 78.3 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) TENA_THI-4 PF03070.11 KEY72941.1 - 9.8e-07 28.7 0.0 4.5e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 TENA/THI-4/PQQC family MFS_1 PF07690.11 KEY72942.1 - 2.1e-32 112.1 66.1 6.2e-25 87.6 26.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KEY72942.1 - 0.0018 16.5 21.2 0.005 15.0 3.9 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Transketolase_N PF00456.16 KEY72943.1 - 4.7e-121 403.6 0.0 4.5e-120 400.4 0.0 2.0 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KEY72943.1 - 2.1e-38 131.6 0.0 4.5e-38 130.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 KEY72943.1 - 7.4e-09 34.9 0.0 1.1e-06 27.8 0.0 2.3 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 KEY72943.1 - 6.6e-08 32.5 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 KEY72943.1 - 1.1e-05 24.3 0.3 1.8e-05 23.6 0.2 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component AsmA_2 PF13502.1 KEY72943.1 - 0.01 15.1 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 AsmA-like C-terminal region F_bP_aldolase PF01116.15 KEY72944.1 - 4.2e-73 245.9 0.0 4.7e-73 245.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Peptidase_C34 PF05413.6 KEY72944.1 - 0.058 13.4 0.0 3.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Putative closterovirus papain-like endopeptidase Fungal_trans_2 PF11951.3 KEY72945.1 - 1.1e-10 40.6 0.0 1.8e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY72945.1 - 4.7e-08 32.8 10.9 8.4e-08 31.9 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KEY72946.1 - 2.4e-25 89.3 0.2 3e-25 89.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY72946.1 - 7.7e-25 88.0 0.0 1e-24 87.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY72946.1 - 2.1e-08 34.0 0.0 3.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.11 KEY72947.1 - 7.6e-39 133.4 31.0 7.6e-39 133.4 21.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily FGGY_N PF00370.16 KEY72947.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Sugar_tr PF00083.19 KEY72948.1 - 1.9e-74 250.9 25.7 2.3e-74 250.6 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY72948.1 - 1.8e-15 56.5 36.2 1.8e-15 56.5 25.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NmrA PF05368.8 KEY72949.1 - 3.5e-17 62.4 0.0 5.4e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY72949.1 - 3.7e-11 43.3 0.0 3.3e-10 40.2 0.0 2.4 3 0 0 3 3 3 1 NADH(P)-binding Epimerase PF01370.16 KEY72949.1 - 0.053 12.9 0.0 0.4 10.0 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family PMC2NT PF08066.7 KEY72950.1 - 0.069 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 PMC2NT (NUC016) domain ACT_3 PF10000.4 KEY72951.1 - 1.1e-18 66.6 0.2 2.1e-18 65.7 0.2 1.4 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.1 KEY72951.1 - 1.2e-09 37.5 0.0 2.4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 ACT domain P5CR_dimer PF14748.1 KEY72952.1 - 1.2e-37 128.1 0.8 3e-37 126.8 0.1 2.0 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KEY72952.1 - 1e-16 61.1 0.7 3.4e-16 59.4 0.5 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KEY72952.1 - 2.1e-05 24.3 4.7 0.00065 19.4 3.3 2.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 KEY72952.1 - 0.056 13.5 0.1 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ERG4_ERG24 PF01222.12 KEY72953.1 - 1e-146 488.8 2.9 1.4e-146 488.4 2.0 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Methyltransf_11 PF08241.7 KEY72953.1 - 1e-21 77.1 0.0 2.7e-21 75.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY72953.1 - 3.2e-18 65.7 0.0 5.3e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY72953.1 - 3.9e-14 52.8 0.0 8.2e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY72953.1 - 6e-14 52.0 0.0 1.2e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY72953.1 - 1e-10 41.1 0.0 2.1e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KEY72953.1 - 2e-10 41.2 0.0 4.8e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KEY72953.1 - 2.5e-10 39.8 0.0 4e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KEY72953.1 - 5.9e-10 39.5 0.0 1.4e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY72953.1 - 2.6e-09 37.1 1.5 1.3e-08 34.9 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KEY72953.1 - 0.00035 19.9 0.0 0.00074 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 KEY72953.1 - 0.0039 16.7 0.0 0.0063 16.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase DUF1295 PF06966.7 KEY72953.1 - 0.0049 16.1 0.6 0.012 14.8 0.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PrmA PF06325.8 KEY72953.1 - 0.021 13.9 0.1 0.078 12.0 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.1 KEY72953.1 - 0.026 15.3 0.0 0.11 13.3 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 KEY72953.1 - 0.037 13.0 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MetW PF07021.7 KEY72953.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.13 KEY72953.1 - 0.14 11.3 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase Cyclin_N PF00134.18 KEY72954.1 - 0.007 15.9 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain BAR PF03114.13 KEY72955.1 - 8.9e-42 143.1 1.6 1.1e-41 142.8 1.1 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 KEY72955.1 - 0.00023 20.2 0.5 0.00031 19.7 0.3 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Myosin_tail_1 PF01576.14 KEY72955.1 - 0.43 8.2 14.4 0.018 12.7 6.1 1.4 2 0 0 2 2 2 0 Myosin tail IncA PF04156.9 KEY72955.1 - 2.6 7.5 4.8 0.77 9.3 1.2 1.6 2 0 0 2 2 2 0 IncA protein zf-LITAF-like PF10601.4 KEY72957.1 - 2.5e-05 24.0 0.7 4.3e-05 23.2 0.5 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain GFA PF04828.9 KEY72957.1 - 0.15 11.9 0.5 0.74 9.8 0.3 2.1 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KEY72957.1 - 4.1 6.7 6.6 4.2 6.7 0.3 2.7 3 0 0 3 3 3 0 zinc-ribbon domain NACHT PF05729.7 KEY72958.1 - 3.2e-07 30.1 0.0 7.5e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 KEY72958.1 - 0.0033 17.1 0.0 0.014 15.1 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KEY72958.1 - 0.0048 17.0 1.0 0.011 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEY72958.1 - 0.0073 16.3 3.1 0.0086 16.0 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.4 KEY72958.1 - 0.0078 15.2 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 KEY72958.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEY72958.1 - 0.66 10.8 0.0 0.66 10.8 0.0 2.6 2 1 1 3 3 3 0 AAA domain HET PF06985.6 KEY72959.1 - 2.6e-21 76.2 0.1 5.7e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 KEY72960.1 - 3.6e-40 137.3 4.2 9e-40 136.0 2.9 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 KEY72960.1 - 3.8e-06 27.1 0.6 1.6e-05 25.1 0.1 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 KEY72960.1 - 2.2e-05 24.0 0.3 0.012 15.4 0.0 3.5 1 1 1 2 2 2 1 Ankyrin repeat Zn_clus PF00172.13 KEY72960.1 - 4e-05 23.4 0.3 9.2e-05 22.2 0.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_4 PF13637.1 KEY72960.1 - 0.0048 17.3 0.3 0.073 13.6 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY72960.1 - 0.11 12.8 0.0 0.6 10.5 0.0 2.4 1 0 0 1 1 1 0 Ankyrin repeat TPR_12 PF13424.1 KEY72960.1 - 0.12 12.3 1.0 0.32 10.9 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_3 PF00933.16 KEY72961.1 - 9.4e-53 179.1 0.0 1.2e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY72961.1 - 2.8e-09 36.8 0.0 1.2e-07 31.5 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain AAA PF00004.24 KEY72962.1 - 1.6e-40 138.3 0.0 1.6e-12 47.7 0.0 5.7 6 0 0 6 6 4 3 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.1 KEY72962.1 - 9.3e-37 126.3 0.5 4.4e-36 124.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KEY72962.1 - 1.8e-26 93.1 33.7 1.8e-25 89.8 0.0 6.9 6 1 0 6 6 5 2 AAA domain AAA_19 PF13245.1 KEY72962.1 - 2e-17 62.7 1.3 8.8e-05 22.1 0.0 5.0 4 0 0 4 4 4 4 Part of AAA domain AAA_22 PF13401.1 KEY72962.1 - 1.5e-12 47.7 10.9 0.015 15.4 0.0 8.0 5 3 0 5 5 5 3 AAA domain AAA_17 PF13207.1 KEY72962.1 - 7.9e-10 39.6 8.6 0.079 13.7 0.0 5.6 5 0 0 5 5 4 3 AAA domain Mg_chelatase PF01078.16 KEY72962.1 - 2.6e-09 36.5 0.1 0.31 10.1 0.0 4.8 4 0 0 4 4 4 3 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KEY72962.1 - 7.3e-08 32.2 4.9 0.86 9.3 0.0 5.3 5 0 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEY72962.1 - 1e-06 28.8 14.2 0.96 9.3 0.0 6.0 6 1 0 6 6 4 4 AAA ATPase domain IstB_IS21 PF01695.12 KEY72962.1 - 1.1e-06 28.2 0.4 5.6 6.3 0.0 4.8 4 0 0 4 4 4 2 IstB-like ATP binding protein AAA_25 PF13481.1 KEY72962.1 - 3.1e-06 26.7 2.0 2.6 7.4 0.0 6.0 5 1 1 6 6 6 1 AAA domain RNA_helicase PF00910.17 KEY72962.1 - 3.3e-06 27.2 0.1 4.2 7.5 0.0 5.0 4 0 0 4 4 4 2 RNA helicase AAA_33 PF13671.1 KEY72962.1 - 6e-06 26.1 6.1 0.39 10.5 0.0 5.1 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.1 KEY72962.1 - 0.0001 22.6 13.9 1.7 8.9 0.0 5.6 5 0 0 5 5 4 3 AAA domain AAA_24 PF13479.1 KEY72962.1 - 0.0019 17.8 13.0 0.83 9.2 0.0 4.7 4 1 0 4 4 4 2 AAA domain AAA_10 PF12846.2 KEY72962.1 - 0.0067 15.9 10.5 19 4.5 0.0 6.2 5 2 0 6 6 6 0 AAA-like domain UvrD_C_2 PF13538.1 KEY72962.1 - 0.0098 16.0 0.2 0.042 13.9 0.0 2.2 2 0 0 2 2 1 1 UvrD-like helicase C-terminal domain Guanylate_cyc_2 PF09778.4 KEY72962.1 - 0.049 12.8 0.0 2.1 7.4 0.0 2.7 3 0 0 3 3 3 0 Guanylylate cyclase AAA_28 PF13521.1 KEY72962.1 - 7.1 6.5 22.7 2.3 8.1 0.0 6.2 6 0 0 6 6 6 0 AAA domain His_Phos_2 PF00328.17 KEY72963.1 - 8.6e-18 64.7 0.0 1.1e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) adh_short PF00106.20 KEY72964.1 - 3.7e-15 56.2 0.1 5.3e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY72964.1 - 4e-10 39.6 0.0 4.6e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Dak1_2 PF13684.1 KEY72964.1 - 0.057 12.3 0.0 0.081 11.8 0.0 1.1 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Ank PF00023.25 KEY72966.1 - 2.5e-21 74.3 2.0 3.2e-06 26.6 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 KEY72966.1 - 1.6e-20 73.2 0.2 2e-20 72.9 0.2 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEY72966.1 - 2.1e-13 49.1 0.9 0.0069 16.5 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KEY72966.1 - 1.5e-10 41.3 0.5 0.041 14.4 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY72966.1 - 2.6e-09 37.0 0.2 0.0013 18.8 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Mic1 PF07035.7 KEY72966.1 - 0.0023 17.3 0.1 2.3 7.5 0.0 2.8 2 1 0 2 2 2 2 Colon cancer-associated protein Mic1-like Gas_vesicle PF00741.13 KEY72966.1 - 0.0023 17.7 5.6 2.5 8.0 0.1 3.1 3 0 0 3 3 3 3 Gas vesicle protein SopE_GEF PF07487.8 KEY72966.1 - 0.11 12.3 0.0 3.2 7.6 0.0 2.4 1 1 1 2 2 2 0 SopE GEF domain HEM4 PF02602.10 KEY72966.1 - 0.13 11.4 0.1 13 4.8 0.0 2.2 1 1 1 2 2 2 0 Uroporphyrinogen-III synthase HemD Nitro_FeMo-Co PF02579.12 KEY72966.1 - 0.14 12.2 0.1 59 3.8 0.0 2.9 1 1 2 3 3 3 0 Dinitrogenase iron-molybdenum cofactor Skp1 PF01466.14 KEY72968.1 - 5.7e-09 35.8 0.3 1e-08 35.0 0.2 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KEY72968.1 - 2.1e-06 27.7 0.0 5.1e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Peptidase_M9_N PF08453.5 KEY72968.1 - 0.0037 16.6 0.3 0.0074 15.6 0.2 1.5 1 0 0 1 1 1 1 Peptidase family M9 N-terminal AAA_12 PF13087.1 KEY72970.1 - 1.1e-40 139.2 0.0 1.8e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KEY72970.1 - 1.9e-25 89.8 0.9 3e-25 89.1 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEY72970.1 - 2e-08 33.8 0.1 4.5e-07 29.5 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 KEY72970.1 - 6.8e-05 22.0 0.1 0.15 10.9 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) zf-CCCH PF00642.19 KEY72970.1 - 0.00011 21.7 5.6 0.00011 21.7 3.9 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_30 PF13604.1 KEY72970.1 - 0.00048 19.7 0.0 0.0045 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEY72970.1 - 0.00071 19.6 0.5 0.005 16.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain UvrD_C_2 PF13538.1 KEY72970.1 - 0.017 15.2 0.0 0.069 13.2 0.0 2.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Peptidase_C32 PF05411.7 KEY72970.1 - 0.021 14.5 0.0 0.067 12.8 0.0 1.8 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase ResIII PF04851.10 KEY72970.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SDH_sah PF01972.11 KEY72970.1 - 0.094 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase DZR PF12773.2 KEY72970.1 - 1.9 8.3 13.0 17 5.2 4.2 3.3 2 1 0 2 2 2 0 Double zinc ribbon UPF0547 PF10571.4 KEY72970.1 - 2.5 7.8 10.7 12 5.7 0.1 4.0 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 DUF1115 PF06544.7 KEY72971.1 - 4.4e-20 71.6 0.0 8.9e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RTA1 PF04479.8 KEY72972.1 - 1.9e-30 106.0 10.8 2.6e-30 105.5 7.5 1.2 1 0 0 1 1 1 1 RTA1 like protein Glycophorin_A PF01102.13 KEY72972.1 - 0.11 12.3 0.5 0.21 11.3 0.4 1.4 1 0 0 1 1 1 0 Glycophorin A HemY_N PF07219.8 KEY72972.1 - 0.24 10.9 2.7 7.1 6.2 0.4 2.5 2 0 0 2 2 2 0 HemY protein N-terminus ABC2_membrane PF01061.19 KEY72973.1 - 1e-89 299.2 60.2 5.8e-46 156.3 19.5 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KEY72973.1 - 2.2e-34 118.7 0.0 3.4e-16 59.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KEY72973.1 - 1.7e-31 107.9 6.3 6.6e-26 89.9 0.0 3.2 3 0 0 3 3 3 2 CDR ABC transporter AAA_25 PF13481.1 KEY72973.1 - 3.4e-07 29.8 0.0 0.017 14.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain cobW PF02492.14 KEY72973.1 - 1.2e-05 24.8 0.1 0.00012 21.5 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 KEY72973.1 - 1.7e-05 24.9 0.1 0.038 13.9 0.0 2.9 2 1 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KEY72973.1 - 3e-05 24.1 0.0 0.12 12.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KEY72973.1 - 3.1e-05 23.4 0.2 0.13 11.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_trans_N PF14510.1 KEY72973.1 - 3.5e-05 23.7 0.1 3.5e-05 23.7 0.0 3.3 3 1 1 4 4 4 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 KEY72973.1 - 3.7e-05 22.9 0.0 0.00058 19.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KEY72973.1 - 0.00011 22.1 1.7 0.011 15.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 KEY72973.1 - 0.00028 20.9 0.6 0.011 15.6 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KEY72973.1 - 0.00028 20.4 0.0 0.99 8.8 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_18 PF13238.1 KEY72973.1 - 0.00033 20.9 0.0 0.015 15.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KEY72973.1 - 0.00046 20.1 0.0 0.18 11.7 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KEY72973.1 - 0.0014 19.3 0.0 0.089 13.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KEY72973.1 - 0.0019 18.2 0.6 0.0066 16.4 0.0 2.3 3 0 0 3 3 1 1 AAA domain ABC2_membrane_3 PF12698.2 KEY72973.1 - 0.0053 15.8 37.3 0.11 11.5 12.4 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein SMC_N PF02463.14 KEY72973.1 - 0.0054 15.9 1.5 0.045 12.9 0.0 2.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 KEY72973.1 - 0.015 14.9 0.3 0.15 11.6 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KEY72973.1 - 0.017 14.7 0.2 0.8 9.3 0.2 2.4 2 0 0 2 2 2 0 NACHT domain APS_kinase PF01583.15 KEY72973.1 - 0.023 14.3 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_24 PF13479.1 KEY72973.1 - 0.032 13.8 0.1 0.32 10.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KEY72973.1 - 0.041 13.3 0.3 0.31 10.5 0.2 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 KEY72973.1 - 0.047 12.5 0.3 3.9 6.2 0.2 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_10 PF12846.2 KEY72973.1 - 0.058 12.8 3.2 7.5 5.8 0.2 3.6 4 0 0 4 4 4 0 AAA-like domain Septin PF00735.13 KEY72973.1 - 0.062 12.3 0.1 0.32 9.9 0.1 2.0 2 0 0 2 2 2 0 Septin ArgK PF03308.11 KEY72973.1 - 0.084 11.6 0.3 5.3 5.7 0.1 2.6 3 0 0 3 3 3 0 ArgK protein T2SE PF00437.15 KEY72973.1 - 0.093 11.6 0.1 7.1 5.4 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Miro PF08477.8 KEY72973.1 - 0.1 13.0 0.0 2.1 8.8 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein GBP PF02263.14 KEY72973.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Arch_ATPase PF01637.13 KEY72973.1 - 0.16 11.6 0.0 34 4.0 0.0 2.9 3 0 0 3 3 3 0 Archaeal ATPase AAA_15 PF13175.1 KEY72973.1 - 0.2 10.6 0.0 19 4.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Ank_2 PF12796.2 KEY72974.1 - 1.1e-98 323.7 25.4 5.7e-21 74.6 0.1 5.7 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KEY72974.1 - 5.6e-49 161.6 24.1 1.3e-06 27.9 0.0 10.8 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.1 KEY72974.1 - 4.7e-48 160.7 24.4 3.9e-09 36.7 0.1 8.2 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY72974.1 - 1.2e-36 121.1 11.5 0.00044 20.2 0.0 11.2 11 0 0 11 11 10 8 Ankyrin repeat Ank_5 PF13857.1 KEY72974.1 - 1.1e-34 117.5 13.0 6.8e-08 32.5 0.1 9.7 3 2 8 11 11 10 8 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 KEY72974.1 - 7.7e-12 44.6 0.2 2.2e-11 43.1 0.1 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 KEY72974.1 - 1.8e-11 43.9 0.1 3.5e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEY72974.1 - 8.1e-07 29.1 1.1 2e-06 27.9 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEY72974.1 - 4.9e-05 23.4 0.1 0.00024 21.2 0.0 2.2 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.17 KEY72974.1 - 0.00029 19.7 0.0 0.00052 18.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 KEY72974.1 - 0.00046 19.9 0.0 0.0008 19.1 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase RNA_helicase PF00910.17 KEY72974.1 - 0.17 12.0 0.0 0.46 10.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF1843 PF08898.5 KEY72974.1 - 0.66 10.0 3.6 46 4.1 0.0 4.0 3 1 1 4 4 3 0 Domain of unknown function (DUF1843) NACHT PF05729.7 KEY72976.1 - 0.0042 16.7 0.0 0.012 15.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain SNF2_N PF00176.18 KEY72977.1 - 1.3e-47 162.0 0.0 1.5e-46 158.5 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain p450 PF00067.17 KEY72978.1 - 9.3e-26 90.3 0.0 1.5e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DIM PF08194.7 KEY72979.1 - 0.051 13.5 0.2 0.099 12.6 0.2 1.4 1 0 0 1 1 1 0 DIM protein Peptidase_S10 PF00450.17 KEY72980.1 - 8.4e-62 209.6 0.1 1.2e-61 209.1 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Herpes_glycop PF01528.11 KEY72980.1 - 0.06 12.0 0.1 0.1 11.2 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Tetraspannin PF00335.15 KEY72983.1 - 2.7e-07 30.0 0.1 4.7e-07 29.2 0.1 1.5 1 1 0 1 1 1 1 Tetraspanin family DUF1772 PF08592.6 KEY72983.1 - 0.26 11.0 5.3 0.093 12.4 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Alpha_GJ PF03229.8 KEY72984.1 - 4 7.7 12.6 2.9 8.2 6.8 2.0 2 0 0 2 2 2 0 Alphavirus glycoprotein J Herpes_capsid PF06112.6 KEY72984.1 - 4.9 7.1 9.9 7.6 6.5 6.9 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Tup_N PF08581.5 KEY72986.1 - 0.074 13.2 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Tup N-terminal Pkinase PF00069.20 KEY72987.1 - 1.3e-08 34.2 0.0 2.8e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 KEY72987.1 - 0.0025 17.4 1.0 0.0063 16.1 0.0 1.8 1 1 0 2 2 2 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 KEY72987.1 - 0.0043 16.1 0.0 0.0086 15.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEY72987.1 - 0.12 12.0 0.1 0.12 12.0 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family TBPIP PF07106.8 KEY72987.1 - 0.22 11.0 0.1 0.33 10.4 0.1 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF925 PF06042.6 KEY72988.1 - 5.9e-47 159.2 0.0 7e-47 159.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF925) MFS_1 PF07690.11 KEY72989.1 - 3.8e-16 58.7 53.9 2e-12 46.5 26.3 3.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KEY72989.1 - 0.014 13.6 17.6 0.018 13.2 8.1 2.6 1 1 1 2 2 2 0 Fungal trichothecene efflux pump (TRI12) SapB_1 PF05184.10 KEY72990.1 - 0.057 13.2 1.5 0.058 13.2 0.0 1.7 2 0 0 2 2 2 0 Saposin-like type B, region 1 Rad4 PF03835.10 KEY72991.1 - 0.087 12.2 0.1 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain FMN_dh PF01070.13 KEY72992.1 - 4e-85 285.7 0.1 9.2e-74 248.4 0.0 3.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KEY72992.1 - 0.0013 17.7 0.0 0.0021 17.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KEY72992.1 - 0.0048 15.8 0.0 0.0097 14.8 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 KEY72992.1 - 0.0065 15.7 0.0 7.5 5.7 0.0 3.0 3 0 0 3 3 3 1 Histidine biosynthesis protein DHO_dh PF01180.16 KEY72992.1 - 0.012 14.6 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase GRP PF07172.6 KEY72993.1 - 0.015 15.7 18.6 0.021 15.3 12.9 1.3 1 0 0 1 1 1 0 Glycine rich protein family NmrA PF05368.8 KEY72995.1 - 3.9e-64 216.0 0.0 4.7e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY72995.1 - 6.6e-15 55.5 0.7 9.7e-15 55.0 0.5 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEY72995.1 - 0.0021 16.7 0.0 0.0033 16.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KEY72995.1 - 0.015 14.7 0.1 0.025 14.0 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CIAPIN1 PF05093.8 KEY72996.1 - 2.8e-36 123.6 3.5 4.1e-36 123.0 2.4 1.2 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Fasciclin PF02469.17 KEY72997.1 - 6.9e-43 145.7 0.2 5.4e-26 91.0 0.1 2.2 2 0 0 2 2 2 2 Fasciclin domain Sugar_tr PF00083.19 KEY72999.1 - 1.1e-70 238.4 17.1 1.3e-70 238.2 11.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY72999.1 - 1e-27 96.8 17.8 1.6e-27 96.1 12.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KEY72999.1 - 2.4e-07 29.3 0.3 4e-07 28.6 0.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KEY72999.1 - 1.6e-05 23.5 0.2 1.6e-05 23.5 0.1 3.0 3 0 0 3 3 3 1 MFS/sugar transport protein OATP PF03137.15 KEY72999.1 - 4.9e-05 21.5 0.2 9.2e-05 20.6 0.1 1.3 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_18 PF00704.23 KEY73000.1 - 2e-09 37.3 0.7 2.5e-09 37.0 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 APH PF01636.18 KEY73001.1 - 2.8e-16 59.9 0.1 6.7e-16 58.7 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KEY73001.1 - 0.022 13.7 0.0 0.061 12.2 0.0 1.6 2 0 0 2 2 2 0 Fructosamine kinase Choline_kinase PF01633.15 KEY73001.1 - 0.052 13.1 0.0 0.15 11.6 0.0 1.8 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF1399 PF07173.7 KEY73003.1 - 1.8e-22 80.1 2.6 1.4e-18 67.5 0.0 3.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1399) Lipase_3 PF01764.20 KEY73003.1 - 4.5e-15 55.4 0.0 8.7e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KEY73003.1 - 0.0099 15.6 0.2 0.029 14.1 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Cellulase PF00150.13 KEY73006.1 - 2e-16 60.0 2.3 2.7e-16 59.6 1.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF45 PF01863.12 KEY73006.1 - 0.13 12.0 0.2 14 5.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF45 GFO_IDH_MocA PF01408.17 KEY73007.1 - 2.6e-12 47.3 0.0 4.7e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 KEY73007.1 - 0.00089 19.6 0.1 0.0023 18.2 0.0 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.12 KEY73007.1 - 0.078 12.7 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Bac_rhodopsin PF01036.13 KEY73008.1 - 6.2e-50 169.5 13.8 1e-49 168.8 9.6 1.3 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein GFO_IDH_MocA_C PF02894.12 KEY73008.1 - 3.6e-16 58.9 1.1 5.6e-16 58.3 0.2 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.17 KEY73008.1 - 5.3e-15 55.9 0.0 2.3e-14 53.9 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold DUF2754 PF10953.3 KEY73008.1 - 0.11 12.5 2.7 0.31 11.1 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) MFS_1 PF07690.11 KEY73009.1 - 7.2e-33 113.7 30.9 9.7e-33 113.3 21.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3017 PF11222.3 KEY73009.1 - 0.28 11.0 4.6 0.87 9.4 0.7 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3017) NmrA PF05368.8 KEY73012.1 - 7.8e-16 58.0 0.0 1.1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY73012.1 - 8.8e-16 58.4 0.2 1.5e-15 57.7 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KEY73012.1 - 0.0007 19.8 0.2 0.002 18.4 0.1 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KEY73012.1 - 0.0076 16.1 0.2 0.019 14.8 0.1 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 KEY73012.1 - 0.019 13.7 0.0 0.029 13.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KEY73012.1 - 0.019 14.3 0.1 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 KEY73012.1 - 0.02 15.3 0.5 0.061 13.7 0.1 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Toxin_62 PF15540.1 KEY73012.1 - 0.035 14.2 0.1 0.066 13.3 0.1 1.4 1 0 0 1 1 1 0 Putative toxin 62 adh_short PF00106.20 KEY73012.1 - 0.061 13.2 0.9 0.19 11.6 0.4 2.0 2 1 0 2 2 2 0 short chain dehydrogenase Ldh_1_N PF00056.18 KEY73012.1 - 0.062 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain KR PF08659.5 KEY73012.1 - 0.07 12.7 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 KR domain DUF3336 PF11815.3 KEY73013.1 - 5.3e-40 136.2 2.6 1.2e-39 135.1 1.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KEY73013.1 - 1.5e-23 83.8 0.0 3.2e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase AhpC-TSA PF00578.16 KEY73014.1 - 4.1e-31 107.2 0.0 5.4e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 KEY73014.1 - 2.7e-13 49.3 0.1 4.9e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 KEY73014.1 - 2.9e-13 49.5 0.0 3.9e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin Herpes_V23 PF01802.12 KEY73014.1 - 0.096 11.7 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein Kelch_4 PF13418.1 KEY73015.1 - 1.2e-21 76.1 0.5 1.4e-09 37.6 0.0 5.2 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.1 KEY73015.1 - 2.8e-20 71.9 10.1 8.5e-11 41.7 0.0 6.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.1 KEY73015.1 - 1.7e-13 50.1 5.5 7.1e-05 22.8 0.8 4.8 3 1 1 4 4 4 3 Kelch motif Kelch_2 PF07646.10 KEY73015.1 - 2.2e-12 46.2 1.1 3.9e-05 23.2 0.0 5.1 5 1 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 KEY73015.1 - 4.2e-11 42.2 0.0 0.0016 17.9 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 KEY73015.1 - 5e-11 42.2 6.4 4.3e-05 23.3 0.1 4.1 3 1 0 3 3 3 2 Kelch motif BTB PF00651.26 KEY73015.1 - 0.012 15.5 0.0 0.27 11.2 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain AMP-binding PF00501.23 KEY73016.1 - 1.2e-73 247.8 0.0 1.6e-73 247.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEY73016.1 - 3.1e-11 44.0 0.1 8.7e-11 42.6 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PIG-S PF10510.4 KEY73017.1 - 3e-143 478.2 0.0 3.5e-143 478.0 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Abhydrolase_5 PF12695.2 KEY73018.1 - 1.9e-07 30.9 0.2 1.3e-06 28.2 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY73018.1 - 2.8e-07 30.6 4.6 7.1e-06 26.0 3.2 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KEY73018.1 - 9.9e-05 21.8 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 KEY73018.1 - 0.0028 17.4 0.1 0.0076 16.0 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KEY73018.1 - 0.11 11.6 0.0 0.54 9.4 0.0 2.1 3 0 0 3 3 3 0 Prolyl oligopeptidase family Adeno_PIX PF03955.9 KEY73018.1 - 0.14 12.6 0.2 0.83 10.2 0.1 2.2 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Myb_DNA-bind_6 PF13921.1 KEY73019.1 - 0.00093 19.2 0.4 0.0021 18.1 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KEY73019.1 - 0.079 13.0 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain BAF1_ABF1 PF04684.8 KEY73019.1 - 0.35 9.6 12.0 0.52 9.1 8.3 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4456 PF14644.1 KEY73019.1 - 1.4 8.1 7.7 2.2 7.4 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) PAT1 PF09770.4 KEY73019.1 - 2.2 6.3 10.2 1.2 7.3 1.1 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 UbiA PF01040.13 KEY73020.1 - 1.9e-29 102.6 20.7 4.9e-29 101.3 14.2 1.8 2 0 0 2 2 2 1 UbiA prenyltransferase family DUF3459 PF11941.3 KEY73020.1 - 0.001 19.1 1.8 0.013 15.5 0.1 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3459) TMEM238 PF15125.1 KEY73020.1 - 0.049 13.5 0.3 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 TMEM238 protein family DUF4235 PF14019.1 KEY73020.1 - 1.5 8.6 7.0 12 5.8 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4235) Transaldolase PF00923.14 KEY73021.1 - 7.5e-43 146.7 0.0 9.6e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Transaldolase SAICAR_synt PF01259.13 KEY73022.1 - 9.7e-81 270.5 0.0 1.2e-80 270.1 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase VCBS PF13517.1 KEY73024.1 - 0.00035 20.8 4.1 0.00035 20.8 2.8 5.5 5 1 0 5 5 5 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ PF01011.16 KEY73024.1 - 0.0075 15.7 0.0 0.2 11.2 0.0 3.2 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_2 PF13360.1 KEY73024.1 - 0.009 15.4 0.0 0.25 10.7 0.0 2.3 2 0 0 2 2 2 1 PQQ-like domain FG-GAP PF01839.18 KEY73024.1 - 0.11 12.2 27.3 0.024 14.3 1.8 5.8 6 0 0 6 6 6 0 FG-GAP repeat PepSY_2 PF13670.1 KEY73024.1 - 0.35 10.7 1.3 6.9 6.6 0.0 2.9 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Fungal_trans PF04082.13 KEY73025.1 - 4.8e-19 68.2 0.0 1e-18 67.1 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY73025.1 - 1.6e-06 27.9 16.7 2.8e-06 27.1 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_88 PF07470.8 KEY73026.1 - 1.1e-07 31.2 0.8 1.8e-07 30.5 0.5 1.4 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MFS_1 PF07690.11 KEY73027.1 - 2.2e-15 56.2 29.0 2.2e-15 56.2 20.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PLAC8 PF04749.12 KEY73027.1 - 0.71 10.4 6.5 8.4 7.0 0.3 3.4 3 1 0 3 3 3 0 PLAC8 family DUF2264 PF10022.4 KEY73028.1 - 7.4e-122 406.4 0.2 9.6e-122 406.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Fungal_trans_2 PF11951.3 KEY73029.1 - 3.6e-42 144.3 5.2 4.6e-42 143.9 3.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY73029.1 - 1.3e-09 37.7 11.1 2.7e-09 36.7 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arginase PF00491.16 KEY73030.1 - 9.4e-89 297.3 0.0 1.2e-88 297.0 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KEY73030.1 - 0.041 14.0 0.1 0.11 12.7 0.0 1.7 1 1 1 2 2 2 0 UPF0489 domain MatE PF01554.13 KEY73031.1 - 4.8e-50 169.3 22.9 4e-28 98.0 4.3 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 KEY73031.1 - 7e-10 38.8 3.6 7e-10 38.8 2.5 4.0 2 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Dispanin PF04505.7 KEY73031.1 - 0.022 14.2 0.7 0.074 12.5 0.5 1.9 1 0 0 1 1 1 0 Interferon-induced transmembrane protein AA_permease_2 PF13520.1 KEY73032.1 - 2e-47 161.7 47.1 2.6e-47 161.3 32.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEY73032.1 - 9.2e-24 83.6 41.9 1.3e-23 83.1 29.0 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.3 KEY73033.1 - 5.2e-48 163.5 5.1 7.1e-48 163.1 3.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY73033.1 - 2.2e-06 27.4 11.2 4.3e-06 26.5 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.8 KEY73034.1 - 1.6e-21 77.3 0.0 2.4e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Mac PF12464.3 KEY73035.1 - 2.2e-19 69.2 0.2 3.4e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 KEY73035.1 - 1.6e-13 49.4 10.6 8.3e-11 40.8 4.0 3.2 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KEY73035.1 - 4.2e-11 42.2 14.3 2.3e-10 39.8 3.8 2.8 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase GLTT PF01744.15 KEY73036.1 - 0.12 11.8 0.6 0.15 11.5 0.4 1.1 1 0 0 1 1 1 0 GLTT repeat (6 copies) DUF148 PF02520.12 KEY73037.1 - 0.1 12.3 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF148 Pro_Al_protease PF02983.9 KEY73038.1 - 0.00083 19.2 0.1 0.00083 19.2 0.1 2.3 2 1 0 2 2 2 1 Alpha-lytic protease prodomain PAP2 PF01569.16 KEY73040.1 - 1.8e-21 76.1 2.2 1.8e-21 76.1 1.5 2.0 2 1 0 2 2 2 1 PAP2 superfamily BPD_transp_2 PF02653.11 KEY73040.1 - 0.025 13.5 8.6 0.026 13.5 1.1 2.2 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component DUF983 PF06170.7 KEY73040.1 - 0.38 10.8 0.1 0.38 10.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF983) EpuA PF11772.3 KEY73041.1 - 6.8 6.2 7.0 8.2 5.9 3.7 2.0 1 1 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Tyrosinase PF00264.15 KEY73042.1 - 1.2e-40 140.0 0.0 1.5e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Pyr_redox_3 PF13738.1 KEY73043.1 - 2.4e-22 80.0 0.0 6e-22 78.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEY73043.1 - 2.5e-16 58.9 0.1 1.5e-15 56.4 0.1 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KEY73043.1 - 9.1e-12 44.8 0.0 2.4e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KEY73043.1 - 1.1e-11 44.2 0.0 1.1e-07 31.1 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KEY73043.1 - 7.1e-06 25.8 0.0 9.3e-05 22.2 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KEY73043.1 - 6.1e-05 22.9 0.0 0.00072 19.4 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEY73043.1 - 0.00024 20.1 0.0 0.0023 16.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KEY73043.1 - 0.0062 15.6 0.0 0.084 11.9 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 KEY73043.1 - 0.009 15.1 0.0 0.036 13.1 0.0 1.9 2 0 0 2 2 2 1 Thi4 family GARS_N PF02844.10 KEY73043.1 - 0.02 15.3 0.0 0.13 12.7 0.0 2.3 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, N domain HI0933_like PF03486.9 KEY73043.1 - 0.043 12.2 0.0 0.085 11.3 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein Shikimate_DH PF01488.15 KEY73043.1 - 0.073 13.1 0.0 1.7 8.7 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KEY73043.1 - 0.11 12.8 0.0 22 5.5 0.0 2.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HET PF06985.6 KEY73044.1 - 1.4e-22 80.3 0.0 3.8e-22 78.9 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 KEY73045.1 - 2.7e-53 178.2 2.4 2e-20 72.9 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEY73045.1 - 3e-39 130.8 2.2 7.4e-09 34.9 0.1 5.6 4 1 1 5 5 5 5 Ankyrin repeat Ank_3 PF13606.1 KEY73045.1 - 1.6e-30 102.1 0.2 4.4e-07 29.5 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 KEY73045.1 - 3.2e-27 94.4 0.5 7.7e-10 39.0 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY73045.1 - 1.3e-22 79.3 2.4 5.2e-05 23.3 0.1 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) NACHT PF05729.7 KEY73045.1 - 9.9e-12 44.8 0.2 3e-11 43.2 0.1 1.9 2 0 0 2 2 1 1 NACHT domain AAA_16 PF13191.1 KEY73045.1 - 3.9e-06 26.9 0.0 9.6e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.9 KEY73045.1 - 0.00011 21.2 1.4 0.15 11.0 0.1 2.2 1 1 1 2 2 2 2 KAP family P-loop domain NB-ARC PF00931.17 KEY73045.1 - 0.00027 19.8 0.0 0.00044 19.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KEY73045.1 - 0.00049 20.2 0.0 0.0018 18.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain PGAP1 PF07819.8 KEY73045.1 - 0.012 15.2 0.1 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 KEY73045.1 - 0.013 15.3 0.4 0.033 14.0 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family RNA_helicase PF00910.17 KEY73045.1 - 0.029 14.5 0.0 0.072 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 KEY73045.1 - 0.05 12.5 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 KEY73045.1 - 0.053 12.9 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 KEY73045.1 - 0.068 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase CLTH PF10607.4 KEY73045.1 - 0.089 12.4 0.1 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain AAA_19 PF13245.1 KEY73045.1 - 0.096 12.4 0.0 0.32 10.7 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AMP-binding PF00501.23 KEY73046.1 - 3.3e-167 556.1 0.0 1.3e-86 290.6 0.0 2.6 3 0 0 3 3 3 2 AMP-binding enzyme Condensation PF00668.15 KEY73046.1 - 1.3e-129 431.4 0.0 5.7e-34 117.3 0.0 5.0 4 1 0 4 4 4 4 Condensation domain PP-binding PF00550.20 KEY73046.1 - 3.6e-21 75.1 0.1 3.9e-09 36.6 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KEY73046.1 - 3.4e-12 47.1 0.4 3.5e-07 31.0 0.1 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 KEY73046.1 - 0.00044 20.4 0.0 0.13 12.6 0.0 3.6 3 0 0 3 3 3 1 HxxPF-repeated domain UPF0242 PF06785.6 KEY73046.1 - 0.57 8.8 0.0 2.6 6.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) Beta_elim_lyase PF01212.16 KEY73047.1 - 3e-58 197.2 0.0 3.8e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KEY73047.1 - 2.2e-06 26.8 0.0 2.9e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KEY73047.1 - 0.0008 18.5 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KEY73047.1 - 0.0024 16.1 0.0 0.0036 15.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Trp_DMAT PF11991.3 KEY73048.1 - 1.2e-57 195.7 0.0 5.2e-57 193.6 0.0 1.7 2 0 0 2 2 2 1 Tryptophan dimethylallyltransferase p450 PF00067.17 KEY73049.1 - 2.9e-47 161.2 0.0 5.3e-34 117.5 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 KEY73050.1 - 1.2e-66 225.1 0.0 1.5e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RRF_GI PF12614.3 KEY73050.1 - 0.0022 17.7 0.4 0.059 13.1 0.0 2.3 1 1 1 2 2 2 1 Ribosome recycling factor ketoacyl-synt PF00109.21 KEY73051.1 - 2.9e-64 216.9 2.5 2.9e-64 216.9 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEY73051.1 - 8.3e-52 176.4 0.7 1.5e-51 175.6 0.5 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KEY73051.1 - 8.3e-49 165.6 0.0 6e-48 162.8 0.0 2.6 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 KEY73051.1 - 1.8e-43 148.7 0.1 2.9e-43 148.1 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KEY73051.1 - 2.5e-43 147.8 0.3 3.2e-42 144.2 0.0 3.0 3 0 0 3 3 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KEY73051.1 - 1.1e-32 112.3 0.2 3.3e-32 110.8 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KEY73051.1 - 1.7e-20 73.2 0.0 1.2e-19 70.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.21 KEY73051.1 - 9.1e-15 54.3 0.1 2.8e-14 52.7 0.0 1.9 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KEY73051.1 - 6.7e-11 42.1 0.0 1.5e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KEY73051.1 - 3.2e-10 40.1 0.0 9.5e-10 38.6 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 KEY73051.1 - 5e-09 35.9 0.1 1.2e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KEY73051.1 - 2.4e-07 31.6 0.0 1.1e-06 29.6 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 KEY73051.1 - 4.8e-07 29.4 0.0 1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY73051.1 - 2.9e-06 27.8 0.0 1.2e-05 25.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY73051.1 - 4.1e-06 27.1 0.0 6e-05 23.4 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 KEY73051.1 - 0.0019 17.1 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.1 KEY73051.1 - 0.0065 16.8 0.0 0.022 15.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_10 PF13460.1 KEY73051.1 - 0.011 15.7 2.1 0.062 13.2 0.1 2.6 2 0 0 2 2 2 0 NADH(P)-binding 3Beta_HSD PF01073.14 KEY73051.1 - 0.053 12.2 0.0 0.098 11.3 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KEY73051.1 - 0.067 12.1 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Epimerase PF01370.16 KEY73051.1 - 0.095 12.1 0.0 0.29 10.5 0.0 1.8 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ubie_methyltran PF01209.13 KEY73051.1 - 0.16 11.0 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NmrA PF05368.8 KEY73051.1 - 0.34 10.1 1.0 8.7 5.5 0.0 3.0 3 0 0 3 3 3 0 NmrA-like family BAF1_ABF1 PF04684.8 KEY73051.1 - 3.4 6.4 3.3 9.7 4.9 0.1 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Pkinase PF00069.20 KEY73053.1 - 1.2e-26 93.4 0.0 3.2e-26 92.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY73053.1 - 3e-15 56.0 0.0 1.1e-13 50.8 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase AA_permease PF00324.16 KEY73055.1 - 1.7e-24 86.0 37.0 2.2e-19 69.1 13.4 3.1 3 0 0 3 3 3 2 Amino acid permease AA_permease_2 PF13520.1 KEY73055.1 - 8e-10 37.8 19.3 8e-10 37.8 13.4 3.2 3 0 0 3 3 3 2 Amino acid permease Alpha-L-AF_C PF06964.7 KEY73056.1 - 8.1e-35 120.1 1.1 1.3e-34 119.4 0.8 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Glyco_hydro_10 PF00331.15 KEY73057.1 - 3.5e-103 344.9 0.1 4e-103 344.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 KEY73057.1 - 1.4e-13 50.2 13.1 3.9e-13 48.8 9.1 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Cellulase-like PF12876.2 KEY73057.1 - 0.028 14.8 0.0 0.094 13.1 0.0 1.9 1 0 0 1 1 1 0 Sugar-binding cellulase-like YaaC PF14175.1 KEY73057.1 - 0.098 11.6 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 YaaC-like Protein CBM_1 PF00734.13 KEY73058.1 - 6.1e-13 48.1 17.1 6.1e-13 48.1 11.8 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Abhydrolase_5 PF12695.2 KEY73058.1 - 2.1e-06 27.5 0.2 5.1e-06 26.3 0.1 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEY73058.1 - 3.6e-06 26.3 0.5 3.5e-05 23.1 0.1 2.4 3 0 0 3 3 3 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 KEY73058.1 - 1.5e-05 24.3 0.9 5.8e-05 22.4 0.3 1.9 1 1 1 2 2 2 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.2 KEY73058.1 - 9.3e-05 22.4 0.0 0.00038 20.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KEY73058.1 - 0.0003 20.3 0.0 0.00047 19.6 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.15 KEY73058.1 - 0.0016 17.8 0.7 0.015 14.7 0.5 2.1 1 1 0 1 1 1 1 Putative esterase AXE1 PF05448.7 KEY73058.1 - 0.14 10.5 0.1 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Toxin_7 PF05980.7 KEY73058.1 - 1.4 8.9 8.1 3 7.9 5.6 1.6 1 0 0 1 1 1 0 Toxin 7 Glyco_hydro_3 PF00933.16 KEY73059.1 - 9.2e-58 195.5 0.0 1.4e-57 194.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY73059.1 - 1.3e-34 119.7 0.0 2.2e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEY73059.1 - 2.1e-05 24.3 0.0 4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Polysacc_deac_1 PF01522.16 KEY73060.1 - 5.9e-15 54.9 0.0 1.3e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase ThuA PF06283.6 KEY73060.1 - 0.033 13.9 0.2 0.25 11.0 0.0 2.0 1 1 1 2 2 2 0 Trehalose utilisation PhoD PF09423.5 KEY73061.1 - 1.8e-150 501.5 4.6 2.1e-150 501.2 3.2 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase MFS_1 PF07690.11 KEY73062.1 - 7.8e-32 110.3 18.5 4.3e-31 107.8 11.7 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY73062.1 - 1.9e-07 30.0 3.1 1.9e-07 30.0 2.1 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter DUF3353 PF11833.3 KEY73062.1 - 8.7 5.7 10.0 3.4 7.0 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) Fungal_trans PF04082.13 KEY73063.1 - 2.3e-15 56.2 0.1 3.7e-15 55.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Isochorismatase PF00857.15 KEY73064.1 - 1e-26 93.9 0.0 1.3e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Abhydrolase_3 PF07859.8 KEY73065.1 - 1.9e-55 187.7 0.1 2.6e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KEY73065.1 - 6.4e-13 48.2 0.5 1.4e-12 47.1 0.3 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KEY73065.1 - 0.00017 20.9 0.0 0.00031 20.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEY73065.1 - 0.001 18.8 0.1 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KEY73065.1 - 0.045 12.3 0.0 0.14 10.7 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) DUF2048 PF09752.4 KEY73065.1 - 0.11 11.3 0.1 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) p450 PF00067.17 KEY73066.1 - 4.9e-58 196.7 0.0 7e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 HgmA PF04209.8 KEY73067.1 - 1.1e-135 452.3 0.0 1.4e-135 452.0 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Transp_cyt_pur PF02133.10 KEY73068.1 - 1.3e-29 103.1 32.4 1.4e-28 99.6 22.4 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Peptidase_M43 PF05572.8 KEY73069.1 - 4.7e-08 32.7 0.2 8e-08 32.0 0.1 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 KEY73069.1 - 3e-05 24.1 0.1 4.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KEY73069.1 - 4.4e-05 23.5 0.3 6.7e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KEY73069.1 - 0.0011 18.5 0.3 0.0017 17.9 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KEY73069.1 - 0.0061 16.2 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.1 KEY73069.1 - 0.028 14.9 1.0 0.049 14.1 0.6 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.11 KEY73069.1 - 0.029 14.0 0.2 0.061 13.0 0.0 1.6 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M66 PF10462.4 KEY73069.1 - 0.043 12.6 0.8 0.079 11.8 0.5 1.4 2 0 0 2 2 2 0 Peptidase M66 Peptidase_S8 PF00082.17 KEY73070.1 - 3.4e-18 65.8 0.0 7.4e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Subtilase family Ank_4 PF13637.1 KEY73070.1 - 1.2e-05 25.6 0.1 7.9 7.1 0.0 4.0 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEY73070.1 - 0.00016 21.9 0.0 0.034 14.4 0.0 3.0 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEY73070.1 - 0.0029 17.7 0.0 0.95 9.8 0.0 3.9 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Response_reg PF00072.19 KEY73070.1 - 0.053 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Response regulator receiver domain Ank_2 PF12796.2 KEY73072.1 - 1.9e-93 306.9 17.7 8.9e-14 51.5 0.3 13.0 5 3 9 14 14 14 12 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEY73072.1 - 4.3e-62 205.4 32.0 4.9e-08 33.2 0.0 18.1 15 5 4 19 19 19 12 Ankyrin repeats (many copies) Ank PF00023.25 KEY73072.1 - 1.1e-56 185.9 32.1 1.8e-06 27.4 0.0 22.6 24 0 0 24 24 24 9 Ankyrin repeat Ank_3 PF13606.1 KEY73072.1 - 1.4e-44 145.5 19.1 0.0001 22.1 0.0 21.0 23 0 0 23 23 21 7 Ankyrin repeat Ank_5 PF13857.1 KEY73072.1 - 3.8e-44 147.7 33.8 9.6e-09 35.2 0.2 16.2 12 5 5 17 17 16 9 Ankyrin repeats (many copies) SPRY PF00622.23 KEY73072.1 - 1.1e-09 38.4 0.0 2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 SPRY domain AAA_16 PF13191.1 KEY73072.1 - 5.4e-05 23.2 0.2 0.00025 21.0 0.2 2.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KEY73072.1 - 0.00039 20.1 0.0 0.001 18.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KEY73072.1 - 0.0034 17.5 0.0 0.023 14.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KEY73072.1 - 0.0056 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF937 PF06078.6 KEY73072.1 - 0.083 13.1 4.5 0.089 13.0 0.7 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF937) Arch_ATPase PF01637.13 KEY73072.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase RNA12 PF10443.4 KEY73072.1 - 0.22 9.9 0.0 0.35 9.2 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein Myosin_head PF00063.16 KEY73072.1 - 1.4 6.8 0.0 2.2 6.2 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) MFS_1 PF07690.11 KEY73074.1 - 7.9e-38 130.0 33.4 7.9e-38 130.0 23.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_61 PF03443.9 KEY73075.1 - 3.3e-41 141.4 0.0 4e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KEY73075.1 - 1.6e-11 43.6 14.8 5e-11 42.0 10.2 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KEY73075.1 - 0.47 10.5 10.0 2.2 8.3 6.9 2.1 1 1 0 1 1 1 0 Toxin 7 Frag1 PF10277.4 KEY73077.1 - 1.2e-42 145.7 13.8 1.4e-42 145.5 9.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family PUCC PF03209.10 KEY73077.1 - 0.01 14.6 1.2 0.53 8.9 0.0 2.4 3 0 0 3 3 3 0 PUCC protein CBM_2 PF00553.14 KEY73077.1 - 0.038 14.0 0.3 0.061 13.3 0.2 1.2 1 0 0 1 1 1 0 Cellulose binding domain 7TM_GPCR_Srh PF10318.4 KEY73077.1 - 0.54 9.0 7.4 0.95 8.2 5.2 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh Abi PF02517.11 KEY73077.1 - 0.6 10.2 9.2 1.1e+02 3.0 6.4 3.1 1 1 0 1 1 1 0 CAAX protease self-immunity PhaG_MnhG_YufB PF03334.9 KEY73077.1 - 5.9 7.0 11.7 1.2 9.2 5.1 2.3 2 1 0 2 2 2 0 Na+/H+ antiporter subunit NmrA PF05368.8 KEY73078.1 - 2.6e-33 115.2 0.0 3e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY73078.1 - 8.4e-09 35.6 0.0 1.2e-08 35.1 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEY73078.1 - 5.1e-05 22.8 0.0 8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KEY73078.1 - 0.00015 21.4 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KEY73078.1 - 0.00019 20.2 0.0 0.00028 19.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KEY73078.1 - 0.00027 21.2 0.0 0.00045 20.4 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 KEY73078.1 - 0.00031 20.6 0.1 0.00047 20.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 KEY73078.1 - 0.00034 19.7 0.2 0.00089 18.3 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 KEY73078.1 - 0.0048 17.2 0.1 0.009 16.4 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KEY73078.1 - 0.0064 16.4 0.0 0.0098 15.8 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.15 KEY73078.1 - 0.03 14.4 0.1 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ketoacyl-synt PF00109.21 KEY73082.1 - 0.0078 15.7 0.0 0.0092 15.4 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain COesterase PF00135.23 KEY73083.1 - 1e-75 255.4 0.0 1.6e-75 254.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEY73083.1 - 4.4e-14 52.5 0.1 1.3e-13 51.0 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEY73083.1 - 0.0063 15.7 0.3 0.012 14.8 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DDE_Tnp_1_7 PF13843.1 KEY73084.1 - 5.3e-07 29.0 0.0 7.8e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 MEA1 PF06910.6 KEY73084.1 - 0.019 14.6 0.9 0.03 14.0 0.6 1.2 1 0 0 1 1 1 0 Male enhanced antigen 1 (MEA1) RSN1_TM PF13967.1 KEY73085.1 - 0.048 13.2 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Aminotran_5 PF00266.14 KEY73086.1 - 2e-39 135.4 0.0 2.7e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DUF3227 PF11537.3 KEY73087.1 - 0.15 12.2 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3227) Git3 PF11710.3 KEY73088.1 - 1.2e-18 67.3 4.7 3.7e-18 65.8 3.3 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KEY73088.1 - 1.3e-05 24.4 0.2 1.8e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 KEY73088.1 - 9e-05 22.1 0.1 0.00033 20.3 0.0 2.0 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.6 KEY73088.1 - 0.00066 18.6 4.5 0.0073 15.2 1.5 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Ribonuc_L-PSP PF01042.16 KEY73089.1 - 9.3e-14 51.2 0.0 1.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP CN_hydrolase PF00795.17 KEY73090.1 - 3.9e-27 94.8 0.0 5.1e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Esterase_phd PF10503.4 KEY73091.1 - 7.7e-24 84.1 0.6 1.2e-23 83.5 0.4 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KEY73091.1 - 3.2e-15 55.9 0.5 5.1e-15 55.2 0.3 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family CBM_1 PF00734.13 KEY73091.1 - 2.3e-11 43.1 11.5 2.3e-11 43.1 8.0 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain Abhydrolase_5 PF12695.2 KEY73091.1 - 8.9e-11 41.7 0.1 1.2e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY73091.1 - 4e-09 36.7 0.3 1.3e-08 34.9 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY73091.1 - 8.5e-06 25.4 0.0 1.3e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 KEY73091.1 - 0.00018 21.0 0.2 0.00028 20.4 0.2 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S10 PF00450.17 KEY73091.1 - 0.00075 18.7 0.0 0.0015 17.8 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_3 PF07859.8 KEY73091.1 - 0.0009 18.8 0.1 0.0017 17.9 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S28 PF05577.7 KEY73091.1 - 0.0024 16.5 0.1 0.0036 15.9 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 COesterase PF00135.23 KEY73091.1 - 0.0072 15.0 0.3 0.012 14.3 0.2 1.3 1 0 0 1 1 1 1 Carboxylesterase family BAAT_C PF08840.6 KEY73091.1 - 0.022 14.4 0.1 0.039 13.6 0.1 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 KEY73091.1 - 0.051 12.8 0.2 0.12 11.5 0.1 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family AXE1 PF05448.7 KEY73091.1 - 0.065 11.7 0.1 0.12 10.8 0.1 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Toxin_7 PF05980.7 KEY73091.1 - 0.46 10.5 6.5 0.16 12.0 2.1 2.0 2 0 0 2 2 2 0 Toxin 7 HET PF06985.6 KEY73092.1 - 2.9e-21 76.0 3.7 4.5e-18 65.7 0.2 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Amidohydro_1 PF01979.15 KEY73093.1 - 1.1e-34 120.6 0.0 4.9e-34 118.4 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 KEY73093.1 - 6.6e-11 42.7 0.5 6e-06 26.4 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 KEY73093.1 - 1e-10 41.3 2.1 6.7e-07 28.8 0.0 3.1 2 1 1 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 KEY73093.1 - 1.1e-06 28.3 0.0 3e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase YlbD_coat PF14071.1 KEY73093.1 - 0.03 14.3 0.0 9.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Putative coat protein OTT_1508_deam PF14441.1 KEY73094.1 - 8e-20 71.1 0.0 1.8e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase DNA_topoisoIV PF00521.15 KEY73095.1 - 0.16 10.7 0.2 0.24 10.1 0.1 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DLH PF01738.13 KEY73096.1 - 4.8e-18 65.2 0.0 1.4e-17 63.6 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KEY73096.1 - 3.4e-06 26.8 0.0 5.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ribonuclease_T2 PF00445.13 KEY73098.1 - 5.4e-42 143.5 0.0 8.5e-42 142.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family IncA PF04156.9 KEY73099.1 - 0.0063 16.1 14.9 0.16 11.5 1.5 2.3 2 0 0 2 2 2 2 IncA protein GldM_N PF12081.3 KEY73099.1 - 0.01 15.4 6.6 0.31 10.5 1.0 2.2 2 0 0 2 2 2 0 GldM N-terminal domain Baculo_PEP_C PF04513.7 KEY73099.1 - 0.014 15.1 6.7 0.077 12.8 0.9 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.7 KEY73099.1 - 0.017 14.8 15.8 0.26 11.0 3.8 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Filament PF00038.16 KEY73099.1 - 0.017 14.6 8.8 0.037 13.5 0.2 2.3 2 0 0 2 2 2 0 Intermediate filament protein DUF4407 PF14362.1 KEY73099.1 - 0.029 13.3 5.3 0.051 12.5 3.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Prefoldin_2 PF01920.15 KEY73099.1 - 0.031 14.0 8.3 0.091 12.5 0.1 3.2 2 1 1 3 3 3 0 Prefoldin subunit Atg14 PF10186.4 KEY73099.1 - 0.046 12.6 12.4 0.75 8.6 3.7 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ATG16 PF08614.6 KEY73099.1 - 0.059 13.1 13.3 0.033 13.9 2.6 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.3 KEY73099.1 - 0.061 13.0 11.6 0.4 10.4 1.3 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding GAS PF13851.1 KEY73099.1 - 0.071 12.2 10.8 1 8.4 2.4 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2730 PF10805.3 KEY73099.1 - 0.13 12.0 2.6 1.4 8.7 0.0 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) DUF4446 PF14584.1 KEY73099.1 - 0.18 11.6 4.8 0.26 11.1 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) AAA_23 PF13476.1 KEY73099.1 - 0.31 11.3 2.5 0.61 10.3 1.7 1.5 1 0 0 1 1 1 0 AAA domain Striatin PF08232.7 KEY73099.1 - 0.41 10.9 8.9 2.7 8.3 2.8 2.4 2 0 0 2 2 2 0 Striatin family COG5 PF10392.4 KEY73099.1 - 0.54 10.2 8.0 1.8 8.4 4.8 2.3 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF972 PF06156.8 KEY73099.1 - 0.66 10.3 12.2 2.4 8.5 1.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Spc7 PF08317.6 KEY73099.1 - 0.66 8.5 16.9 0.3 9.6 3.3 2.2 1 1 0 2 2 2 0 Spc7 kinetochore protein EMP24_GP25L PF01105.19 KEY73099.1 - 0.76 9.4 5.0 1.1 8.9 0.3 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Syntaxin_2 PF14523.1 KEY73099.1 - 0.82 9.7 10.1 1.8 8.6 1.4 2.5 2 0 0 2 2 2 0 Syntaxin-like protein RmuC PF02646.11 KEY73099.1 - 0.88 8.3 8.2 0.28 9.9 1.4 2.2 2 0 0 2 2 2 0 RmuC family bZIP_1 PF00170.16 KEY73099.1 - 0.89 9.5 7.0 3.1 7.8 0.2 3.3 3 0 0 3 3 3 0 bZIP transcription factor Syntaxin PF00804.20 KEY73099.1 - 1.1 9.4 11.7 0.9 9.7 5.9 2.4 1 1 1 2 2 2 0 Syntaxin DUF1515 PF07439.6 KEY73099.1 - 1.1 9.1 7.7 6.4 6.6 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Occludin_ELL PF07303.8 KEY73099.1 - 1.8 9.3 5.5 7.1 7.4 0.7 2.7 2 1 1 3 3 3 0 Occludin homology domain Microtub_assoc PF07989.6 KEY73099.1 - 2 8.3 6.9 1.5 8.6 0.9 3.1 2 2 0 2 2 2 0 Microtubule associated DUF724 PF05266.9 KEY73099.1 - 2.2 7.8 8.7 0.42 10.2 2.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Phage_GPO PF05929.6 KEY73099.1 - 2.4 7.3 7.8 3.8 6.6 4.5 1.7 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase PEP-utilisers_N PF05524.8 KEY73099.1 - 2.8 7.7 9.8 4.2 7.1 1.7 2.5 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF904 PF06005.7 KEY73099.1 - 2.9 8.2 14.3 9 6.6 2.8 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF904) FliD_C PF07195.7 KEY73099.1 - 3.6 6.8 8.8 2 7.6 1.6 2.3 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Spc24 PF08286.6 KEY73099.1 - 6.7 6.4 14.6 6.2 6.5 0.8 3.3 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Fib_alpha PF08702.5 KEY73099.1 - 7.2 6.7 13.3 7.6 6.6 2.8 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family FliT PF05400.8 KEY73099.1 - 9 6.7 17.6 4 7.9 3.2 3.2 2 1 1 3 3 3 0 Flagellar protein FliT TMF_DNA_bd PF12329.3 KEY73099.1 - 9.6 6.1 18.6 12 5.7 1.7 3.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding p450 PF00067.17 KEY73100.1 - 1.7e-49 168.5 0.0 2.7e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 CAP PF00188.21 KEY73102.1 - 2.2e-20 73.4 3.5 3.1e-20 72.9 2.5 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DEC-1_C PF04626.8 KEY73102.1 - 0.12 12.5 0.7 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 Dec-1 protein, C terminal region DUF4106 PF13388.1 KEY73102.1 - 3.6 6.4 7.0 4.6 6.0 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) CHCH PF06747.8 KEY73104.1 - 1.4e-09 37.6 12.9 3.5e-08 33.1 2.4 2.5 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.5 KEY73104.1 - 0.00075 19.2 8.6 0.12 12.1 0.2 2.3 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 KEY73104.1 - 0.46 10.5 8.8 2.1 8.4 4.2 2.4 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Nup54 PF13874.1 KEY73105.1 - 4.2e-42 143.1 0.3 4.2e-42 143.1 0.2 2.4 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 DUF4407 PF14362.1 KEY73105.1 - 0.011 14.7 4.8 0.019 13.9 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DivIVA PF05103.8 KEY73105.1 - 0.013 15.5 1.5 0.013 15.5 1.1 2.4 2 1 1 3 3 3 0 DivIVA protein APG6 PF04111.7 KEY73105.1 - 0.03 13.3 5.2 0.082 11.9 3.4 1.8 1 1 1 2 2 2 0 Autophagy protein Apg6 Tup_N PF08581.5 KEY73105.1 - 0.051 13.7 4.2 0.37 10.9 0.6 2.6 2 0 0 2 2 2 0 Tup N-terminal Nucleoporin_FG PF13634.1 KEY73105.1 - 0.14 12.4 14.8 0.22 11.7 10.3 1.2 1 0 0 1 1 1 0 Nucleoporin FG repeat region Sipho_Gp157 PF05565.6 KEY73105.1 - 0.56 9.7 4.2 0.44 10.1 0.5 2.2 2 1 0 2 2 2 0 Siphovirus Gp157 bZIP_1 PF00170.16 KEY73105.1 - 0.91 9.5 6.1 4.4 7.3 0.3 2.9 2 1 0 2 2 2 0 bZIP transcription factor FlaC_arch PF05377.6 KEY73105.1 - 0.99 9.3 4.1 3.8 7.4 0.1 3.0 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) UPF0184 PF03670.8 KEY73105.1 - 1.2 9.4 0.0 1.2 9.4 0.0 3.0 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0184) Mnd1 PF03962.10 KEY73105.1 - 2.4 7.7 10.3 0.54 9.9 1.3 3.0 2 1 1 3 3 3 0 Mnd1 family GAS PF13851.1 KEY73105.1 - 2.6 7.1 8.3 8.5 5.5 1.8 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 KEY73105.1 - 3.9 7.3 7.3 13 5.7 0.8 2.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 KEY73105.1 - 9.4 6.0 12.6 7.7 6.3 1.1 3.1 2 2 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GDC-P PF02347.11 KEY73106.1 - 4.5e-163 542.9 0.1 8.5e-148 492.5 0.0 2.9 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 KEY73106.1 - 1.3e-05 24.4 0.0 2.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase THF_DHG_CYH PF00763.18 KEY73106.1 - 0.12 12.3 0.0 33 4.5 0.0 2.9 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain WD40 PF00400.27 KEY73107.1 - 8.2e-24 82.5 12.1 1.7e-06 27.6 0.0 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat SKG6 PF08693.5 KEY73107.1 - 0.00026 20.2 2.3 0.0007 18.8 1.6 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 KEY73107.1 - 0.079 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) PHD PF00628.24 KEY73108.1 - 9.3e-11 41.2 12.3 9.3e-11 41.2 8.5 1.8 2 0 0 2 2 2 1 PHD-finger PHD_3 PF13922.1 KEY73108.1 - 0.083 13.1 2.2 0.3 11.3 1.5 1.9 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx zf-CpG_bind_C PF12269.3 KEY73108.1 - 0.085 12.3 0.1 0.085 12.3 0.1 2.1 3 0 0 3 3 3 0 CpG binding protein zinc finger C terminal domain SCO1-SenC PF02630.9 KEY73109.1 - 7e-58 195.0 0.0 1e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 KEY73109.1 - 0.006 16.2 0.0 0.0099 15.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Hydrolase_6 PF13344.1 KEY73110.1 - 1e-19 70.2 0.0 2.7e-19 68.9 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEY73110.1 - 2.7e-15 55.8 0.0 6.9e-15 54.5 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KEY73110.1 - 4.8e-08 33.6 0.0 0.04 14.3 0.0 3.2 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KEY73110.1 - 0.00014 22.1 0.0 0.014 15.6 0.0 2.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 KEY73110.1 - 0.027 14.6 0.0 0.41 10.7 0.0 2.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Choline_kinase PF01633.15 KEY73111.1 - 2.2e-59 200.5 0.1 6e-59 199.1 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 KEY73111.1 - 9.7e-20 69.7 0.2 2.6e-19 68.3 0.0 1.9 2 0 0 2 2 2 1 Choline kinase N terminus APH PF01636.18 KEY73111.1 - 1.1e-08 35.1 0.3 1.1e-08 35.1 0.2 2.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family Sec10 PF07393.6 KEY73111.1 - 2.6 6.1 4.1 4.3 5.3 2.8 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec10 BTB PF00651.26 KEY73112.1 - 2.8e-24 85.2 0.4 6.9e-13 48.5 0.1 3.4 4 0 0 4 4 4 2 BTB/POZ domain Ank_2 PF12796.2 KEY73112.1 - 8.9e-09 35.5 0.0 2.2e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KEY73112.1 - 3.5e-08 32.8 0.3 3.9e-05 23.2 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KEY73112.1 - 3.9e-07 30.1 0.0 7.9e-06 25.9 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEY73112.1 - 1.4e-06 28.6 0.0 3.7e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY73112.1 - 6e-06 25.9 0.0 0.031 14.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Pkinase PF00069.20 KEY73113.1 - 1.4e-59 201.3 0.0 2.2e-59 200.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY73113.1 - 1.3e-37 129.3 0.0 5.6e-37 127.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY73113.1 - 2.4e-05 23.4 0.0 4.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEY73113.1 - 0.019 14.7 2.0 0.037 13.7 0.0 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family Macoilin PF09726.4 KEY73113.1 - 0.028 12.7 2.3 0.052 11.8 1.6 1.5 1 0 0 1 1 1 0 Transmembrane protein Ead_Ea22 PF13935.1 KEY73114.1 - 0.034 14.4 0.2 0.044 14.1 0.1 1.3 1 0 0 1 1 1 0 Ead/Ea22-like protein Use1 PF09753.4 KEY73114.1 - 0.06 12.7 0.1 0.17 11.2 0.0 1.7 1 1 1 2 2 2 0 Membrane fusion protein Use1 DUF2365 PF10157.4 KEY73114.1 - 0.076 12.8 0.4 0.11 12.3 0.2 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) BBP1_C PF15272.1 KEY73114.1 - 0.087 12.3 1.9 0.16 11.5 1.3 1.6 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Not3 PF04065.10 KEY73114.1 - 0.1 11.8 1.6 0.1 11.8 0.3 1.5 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Syntaxin PF00804.20 KEY73114.1 - 0.16 12.1 1.8 1.7 8.8 1.3 2.4 1 1 1 2 2 2 0 Syntaxin zf-C2H2 PF00096.21 KEY73117.1 - 1.3e-09 37.8 7.9 0.00013 22.0 0.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KEY73117.1 - 1.9e-05 24.6 6.8 0.00025 21.1 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KEY73117.1 - 7.2e-05 22.8 6.4 0.065 13.5 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KEY73117.1 - 0.0024 17.9 1.7 0.0077 16.3 0.3 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KEY73117.1 - 0.045 13.8 3.5 0.24 11.6 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding MAP1B_neuraxin PF00414.12 KEY73117.1 - 0.18 11.1 1.9 0.58 9.5 1.3 1.9 1 0 0 1 1 1 0 Neuraxin and MAP1B repeat zf-BED PF02892.10 KEY73117.1 - 2.1 8.1 6.2 11 5.8 0.3 2.4 1 1 1 2 2 2 0 BED zinc finger Fungal_trans_2 PF11951.3 KEY73118.1 - 8.1e-31 106.9 0.3 1e-30 106.6 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY73118.1 - 2.3e-06 27.4 8.6 3.4e-06 26.8 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Candida_ALS PF05792.8 KEY73119.1 - 6.4e-25 86.9 2419.5 1.5e-05 25.0 9.2 132.4 125 13 1 126 126 126 90 Candida agglutinin-like (ALS) EST1_DNA_bind PF10373.4 KEY73123.1 - 3.2e-12 46.2 0.0 7.3e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain ThiF PF00899.16 KEY73124.1 - 4.3e-37 126.9 0.0 8.2e-37 126.0 0.0 1.4 1 0 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 KEY73124.1 - 5.7e-05 22.2 0.0 8.8e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Glyco_hydro_17 PF00332.13 KEY73124.1 - 0.0013 17.8 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 UDPG_MGDP_dh_N PF03721.9 KEY73124.1 - 0.14 11.4 0.1 3.2 7.1 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 KEY73124.1 - 0.16 11.4 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TPR_10 PF13374.1 KEY73125.1 - 0.0014 18.4 0.0 0.0058 16.5 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEY73125.1 - 0.0025 17.7 0.6 0.032 14.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Flu_PA PF00603.12 KEY73125.1 - 0.25 9.3 0.0 8.3 4.2 0.0 2.0 2 0 0 2 2 2 0 Influenza RNA-dependent RNA polymerase subunit PA TPR_16 PF13432.1 KEY73125.1 - 1.5 9.6 8.1 1.4 9.6 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Arb2 PF09757.4 KEY73126.1 - 4.9e-17 61.9 0.0 8e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain Thioredox_DsbH PF03190.10 KEY73129.1 - 7.3e-56 188.3 0.0 1.3e-55 187.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 KEY73129.1 - 0.00013 21.9 0.0 0.00033 20.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like DUF1380 PF07128.7 KEY73129.1 - 0.09 12.5 0.1 1.5 8.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1380) DLIC PF05783.6 KEY73130.1 - 1.6e-29 102.9 0.0 3.8e-29 101.6 0.0 1.7 1 1 1 2 2 2 1 Dynein light intermediate chain (DLIC) RRM_1 PF00076.17 KEY73131.1 - 3e-14 52.3 0.1 4.2e-13 48.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY73131.1 - 2e-08 34.1 0.0 4.1e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY73131.1 - 9.7e-05 22.1 0.0 0.00026 20.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3042 PF11240.3 KEY73131.1 - 8.4 6.2 7.3 25 4.7 5.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) WD40 PF00400.27 KEY73132.1 - 4e-09 36.0 1.6 0.0057 16.4 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat IKI3 PF04762.7 KEY73132.1 - 0.0017 16.2 0.0 0.0077 14.1 0.0 1.8 1 1 1 2 2 2 1 IKI3 family Gmad1 PF10647.4 KEY73132.1 - 0.0094 15.3 0.8 1.8 7.9 0.1 2.8 2 1 1 4 4 4 2 Lipoprotein LpqB beta-propeller domain Septin PF00735.13 KEY73133.1 - 6.2e-107 356.8 0.2 1e-106 356.0 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KEY73133.1 - 6e-05 22.9 0.0 0.00013 21.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KEY73133.1 - 0.00061 19.0 0.1 0.0016 17.6 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KEY73133.1 - 0.0014 19.3 2.7 0.014 16.1 0.0 2.8 2 2 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 KEY73133.1 - 0.0024 17.7 3.6 0.9 9.3 0.0 3.0 2 1 1 3 3 3 2 Dynamin family AAA_22 PF13401.1 KEY73133.1 - 0.0093 16.1 0.1 0.037 14.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 KEY73133.1 - 0.03 14.0 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 KEY73133.1 - 0.032 13.6 0.1 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KEY73133.1 - 0.035 13.9 0.0 0.076 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KEY73133.1 - 0.053 14.0 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein FtsK_SpoIIIE PF01580.13 KEY73133.1 - 0.2 11.1 0.0 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family GLE1 PF07817.8 KEY73133.1 - 0.29 10.0 1.3 0.46 9.3 0.9 1.2 1 0 0 1 1 1 0 GLE1-like protein DUF3653 PF12375.3 KEY73133.1 - 0.43 10.8 2.9 10 6.4 1.1 2.8 2 1 0 2 2 2 0 Phage protein V_ATPase_I PF01496.14 KEY73133.1 - 7.4 4.2 5.4 12 3.6 3.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Bax1-I PF01027.15 KEY73134.1 - 1.6e-48 165.0 25.1 1.9e-48 164.8 17.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 TRAM_LAG1_CLN8 PF03798.11 KEY73135.1 - 5e-46 156.7 18.8 5e-46 156.7 13.0 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KEY73135.1 - 2.6e-17 62.0 0.3 5.8e-17 60.9 0.2 1.6 1 0 0 1 1 1 1 TRAM1-like protein Nucleoplasmin PF03066.10 KEY73135.1 - 0.44 10.0 5.0 0.7 9.3 3.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 KEY73135.1 - 1.1 9.4 7.7 2.7 8.2 5.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain AMP-binding PF00501.23 KEY73136.1 - 6.4e-80 268.5 0.0 8.3e-80 268.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEY73136.1 - 6.3e-16 59.0 0.0 1.7e-15 57.7 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Gly_transf_sug PF04488.10 KEY73137.1 - 2e-14 53.8 0.0 4.3e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KEY73137.1 - 0.048 12.1 0.1 1.3 7.3 0.0 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Cu_amine_oxid PF01179.15 KEY73138.1 - 1.1e-142 475.6 0.1 2.2e-142 474.6 0.0 1.5 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KEY73138.1 - 1.7e-09 37.6 0.1 3.1e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 KEY73138.1 - 1.6e-05 24.8 0.0 3.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain QRPTase_C PF01729.14 KEY73139.1 - 2.5e-56 189.8 0.1 3.1e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 KEY73139.1 - 2.2e-20 72.2 0.0 7.2e-20 70.6 0.0 1.9 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Glyco_transf_8 PF01501.15 KEY73140.1 - 0.00018 20.8 0.5 0.0023 17.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KEY73140.1 - 0.0011 18.4 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative TPR_1 PF00515.23 KEY73141.1 - 7.9e-13 47.4 2.0 1.1e-06 27.9 0.0 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEY73141.1 - 3e-12 45.4 11.8 7e-07 28.6 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEY73141.1 - 1.6e-11 43.6 8.9 3.5e-08 32.9 0.0 5.4 4 1 1 5 5 5 1 TPR repeat TPR_12 PF13424.1 KEY73141.1 - 4.5e-10 39.3 9.0 0.0034 17.2 0.3 6.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 KEY73141.1 - 6.2e-06 26.4 7.2 0.16 12.2 0.0 5.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEY73141.1 - 8.9e-06 25.1 0.0 0.5 10.2 0.0 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEY73141.1 - 3.2e-05 24.4 17.8 0.5 11.0 0.0 6.5 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEY73141.1 - 0.00013 22.2 11.0 1.6 9.5 0.0 7.9 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEY73141.1 - 0.0003 20.3 0.2 0.85 9.5 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEY73141.1 - 0.014 15.8 2.1 67 4.2 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 KEY73141.1 - 0.023 14.8 3.9 24 5.4 0.0 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 KEY73141.1 - 0.058 13.2 1.0 5.6 6.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Metallophos PF00149.23 KEY73142.1 - 8.6e-11 41.6 0.0 2e-10 40.4 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEY73142.1 - 7e-08 32.4 0.0 2e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain LigB PF02900.13 KEY73144.1 - 7.2e-45 153.0 0.0 8.4e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Leu_Phe_trans PF03588.9 KEY73144.1 - 0.14 11.2 0.0 0.33 10.0 0.0 1.5 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase IMD PF08397.6 KEY73146.1 - 1.9e-05 24.1 2.6 0.00078 18.8 0.6 2.1 2 0 0 2 2 2 2 IRSp53/MIM homology domain Abhydrolase_2 PF02230.11 KEY73147.1 - 2.6e-46 157.7 0.0 2.9e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KEY73147.1 - 1.1e-11 44.7 0.0 1.7e-11 44.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY73147.1 - 1.6e-11 44.5 0.6 6.8e-07 29.4 0.1 2.6 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 KEY73147.1 - 2.6e-07 30.3 0.0 7.2e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 KEY73147.1 - 1e-05 24.8 0.0 5.9e-05 22.3 0.0 1.9 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KEY73147.1 - 0.00027 20.5 0.0 0.023 14.2 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 KEY73147.1 - 0.0023 17.2 0.0 0.0033 16.7 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Lipase_3 PF01764.20 KEY73147.1 - 0.018 14.6 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydro_lipase PF04083.11 KEY73147.1 - 0.034 13.5 0.0 0.74 9.2 0.0 2.2 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.3 KEY73147.1 - 0.041 13.7 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 Putative lysophospholipase LIP PF03583.9 KEY73147.1 - 0.057 12.6 0.0 3.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase Cutinase PF01083.17 KEY73147.1 - 0.063 13.0 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Cutinase AXE1 PF05448.7 KEY73147.1 - 0.14 10.6 0.0 0.21 10.0 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase PF00756.15 KEY73147.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase LRR_4 PF12799.2 KEY73148.1 - 2.5e-10 39.7 3.2 5e-09 35.5 0.5 2.8 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEY73148.1 - 5e-08 32.5 2.2 1.5e-07 31.0 1.5 1.9 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 KEY73148.1 - 5.4e-05 22.6 6.8 0.2 11.8 0.2 4.9 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 KEY73148.1 - 0.043 13.9 11.7 1 9.8 0.1 5.2 5 0 0 5 5 5 0 Leucine rich repeat Phosducin PF02114.11 KEY73149.1 - 4.1e-11 42.0 0.0 6e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Phosducin Ribosomal_S27e PF01667.12 KEY73150.1 - 2.2e-28 97.5 7.4 2.7e-28 97.2 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 KEY73150.1 - 0.013 15.3 1.4 0.015 15.1 1.0 1.2 1 0 0 1 1 1 0 IBR domain TF_Zn_Ribbon PF08271.7 KEY73150.1 - 0.29 10.4 3.3 0.41 10.0 2.3 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding RNR_inhib PF08591.5 KEY73151.1 - 7.2e-21 74.9 2.3 2.8e-20 73.0 0.0 2.5 3 0 0 3 3 3 1 Ribonucleotide reductase inhibitor COX16 PF14138.1 KEY73152.1 - 9.2e-30 102.6 0.1 1.1e-29 102.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 FAD_binding_3 PF01494.14 KEY73155.1 - 2.2e-07 30.2 0.0 1.1e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Pkinase PF00069.20 KEY73155.1 - 5.6e-06 25.7 0.0 0.00032 19.9 0.0 2.3 1 1 1 2 2 2 1 Protein kinase domain Ank_5 PF13857.1 KEY73155.1 - 0.006 16.7 0.0 0.017 15.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF2949 PF11165.3 KEY73155.1 - 0.023 14.8 0.0 0.073 13.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2949) Pkinase_Tyr PF07714.12 KEY73155.1 - 0.034 13.2 0.3 5 6.1 0.1 2.3 1 1 0 2 2 2 0 Protein tyrosine kinase Ank_2 PF12796.2 KEY73155.1 - 0.07 13.4 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Kdo PF06293.9 KEY73155.1 - 0.074 12.1 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAD_binding_4 PF01565.18 KEY73156.1 - 1.1e-17 63.8 1.5 1.1e-17 63.8 1.1 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KEY73156.1 - 2.4e-12 46.5 1.5 2.6e-11 43.2 0.2 2.4 2 0 0 2 2 2 1 Berberine and berberine like DUF1191 PF06697.7 KEY73156.1 - 0.13 11.1 0.1 2.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) Alpha-amylase PF00128.19 KEY73157.1 - 1.3e-31 110.1 0.1 1.9e-31 109.6 0.1 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 KEY73157.1 - 3.6e-11 43.0 0.1 8.2e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain adh_short PF00106.20 KEY73158.1 - 1.4e-22 80.4 0.0 1.8e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY73158.1 - 5.2e-10 39.5 0.0 7.3e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEY73158.1 - 2e-08 33.9 0.1 6.8e-08 32.2 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KEY73158.1 - 9.1e-07 28.7 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KEY73158.1 - 0.00015 21.8 0.1 0.00029 20.9 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KEY73158.1 - 0.0032 16.4 0.0 0.0053 15.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DUF1776 PF08643.5 KEY73158.1 - 0.019 14.0 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 KEY73158.1 - 0.056 12.3 0.0 0.077 11.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.13 KEY73159.1 - 0.0085 15.0 0.6 0.017 13.9 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Methyltransf_12 PF08242.7 KEY73161.1 - 1.6e-18 67.0 0.0 3.7e-18 65.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY73161.1 - 1.4e-16 60.6 0.0 2.2e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY73161.1 - 4.2e-11 42.6 0.0 7.1e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY73161.1 - 6.6e-09 36.3 0.0 3e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY73161.1 - 8.5e-09 35.7 0.0 2.3e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY73161.1 - 1.6e-05 24.1 0.0 9.3e-05 21.6 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEY73161.1 - 2.4e-05 24.6 0.0 5.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KEY73161.1 - 0.00019 20.9 0.0 0.00035 20.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KEY73161.1 - 0.0021 18.0 0.0 0.0047 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain p450 PF00067.17 KEY73162.1 - 5.2e-54 183.4 0.0 6.5e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GATA PF00320.22 KEY73163.1 - 2.2e-10 39.6 5.3 3.9e-10 38.8 3.7 1.4 1 0 0 1 1 1 1 GATA zinc finger DZR PF12773.2 KEY73163.1 - 0.03 14.1 0.8 0.06 13.1 0.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 KEY73163.1 - 1.5 8.5 4.1 1.4 8.5 1.1 2.1 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Pkinase PF00069.20 KEY73164.1 - 1.2e-27 96.7 0.0 5.3e-24 84.7 0.0 3.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY73164.1 - 7.2e-08 31.8 0.0 0.0051 15.9 0.0 3.8 3 1 0 4 4 4 2 Protein tyrosine kinase Kinase-like PF14531.1 KEY73164.1 - 0.00083 18.3 0.0 0.28 10.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KEY73164.1 - 0.011 15.4 0.1 0.032 13.9 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KEY73164.1 - 0.087 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.20 KEY73165.1 - 3.3e-19 69.4 0.3 4.3e-19 69.0 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY73165.1 - 1e-11 45.0 0.0 1.3e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase p450 PF00067.17 KEY73166.1 - 3.1e-28 98.5 0.0 1.4e-27 96.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.19 KEY73167.1 - 2.1e-05 24.4 0.2 3.5e-05 23.7 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Zn_clus PF00172.13 KEY73168.1 - 1.5e-06 28.0 10.4 2.5e-06 27.2 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEY73168.1 - 0.00015 20.5 1.2 0.00015 20.5 0.8 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain ABC_tran PF00005.22 KEY73169.1 - 1.9e-49 167.4 0.0 8.4e-29 100.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEY73169.1 - 1.3e-32 113.3 26.7 1.4e-22 80.4 9.4 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KEY73169.1 - 1.9e-07 31.3 0.4 0.025 14.5 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 KEY73169.1 - 3.9e-07 30.2 0.4 0.023 14.6 0.2 2.6 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 KEY73169.1 - 6.5e-07 28.8 8.3 0.054 12.7 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KEY73169.1 - 9.1e-07 28.3 0.3 0.021 14.3 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KEY73169.1 - 2.3e-06 27.7 0.1 0.086 12.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 KEY73169.1 - 7.6e-06 25.0 0.1 0.037 12.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF258 PF03193.11 KEY73169.1 - 1.8e-05 23.9 0.4 0.022 13.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 KEY73169.1 - 3e-05 24.5 0.1 0.25 11.8 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_25 PF13481.1 KEY73169.1 - 5.8e-05 22.5 0.0 0.055 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KEY73169.1 - 0.00011 22.5 0.6 0.17 12.1 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KEY73169.1 - 0.00014 21.4 1.1 0.36 10.2 0.1 2.5 2 1 0 2 2 2 2 AAA-like domain ArgK PF03308.11 KEY73169.1 - 0.00052 18.8 1.0 0.041 12.6 0.0 2.7 3 0 0 3 3 3 1 ArgK protein DUF815 PF05673.8 KEY73169.1 - 0.00069 18.6 0.0 0.54 9.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) MMR_HSR1 PF01926.18 KEY73169.1 - 0.00081 19.3 0.0 1 9.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 KEY73169.1 - 0.0066 16.1 0.1 0.058 13.0 0.0 2.4 3 0 0 3 3 2 1 Archaeal ATPase AAA PF00004.24 KEY73169.1 - 0.0072 16.5 0.0 0.19 11.9 0.0 2.8 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 KEY73169.1 - 0.0099 15.4 0.2 0.23 10.9 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein cobW PF02492.14 KEY73169.1 - 0.011 15.1 0.0 0.43 10.0 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 KEY73169.1 - 0.011 15.8 0.0 1.1 9.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase SbcCD_C PF13558.1 KEY73169.1 - 0.014 15.2 0.5 2.5 8.1 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 KEY73169.1 - 0.019 14.8 0.1 0.77 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 KEY73169.1 - 0.021 14.6 1.3 0.051 13.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 KEY73169.1 - 0.023 14.3 1.5 5.5 6.6 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KEY73169.1 - 0.024 15.4 4.2 1.6 9.5 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KEY73169.1 - 0.025 14.8 0.4 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KEY73169.1 - 0.033 13.2 0.1 2 7.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.18 KEY73169.1 - 0.058 13.2 1.6 2.6 7.8 0.1 2.4 2 0 0 2 2 2 0 Dynamin family ATP-synt_ab PF00006.20 KEY73169.1 - 0.06 12.8 0.3 8.7 5.7 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 KEY73169.1 - 0.095 12.3 1.1 3.1 7.4 0.1 2.7 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 KEY73169.1 - 0.12 11.8 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.10 KEY73169.1 - 0.14 11.8 1.3 14 5.3 0.1 2.4 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.1 KEY73169.1 - 0.15 11.9 1.2 0.31 10.9 0.0 2.2 3 0 0 3 3 1 0 AAA domain TrwB_AAD_bind PF10412.4 KEY73169.1 - 0.15 10.6 0.4 6.4 5.2 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Viral_helicase1 PF01443.13 KEY73169.1 - 0.21 11.0 0.2 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KEY73169.1 - 0.23 11.0 2.2 31 4.0 0.1 3.0 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.17 KEY73169.1 - 0.26 10.0 1.5 9.3 5.0 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain Adeno_IVa2 PF02456.10 KEY73169.1 - 0.35 9.4 0.1 1.5 7.3 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein KaiC PF06745.8 KEY73169.1 - 0.49 9.4 1.3 4.8 6.2 0.0 2.7 3 0 0 3 3 3 0 KaiC AMP-binding PF00501.23 KEY73170.1 - 0 1433.2 4.4 1.3e-88 297.2 0.0 5.3 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 KEY73170.1 - 0 1218.2 0.1 1.7e-53 181.4 0.0 10.9 10 1 0 10 10 10 10 Condensation domain PP-binding PF00550.20 KEY73170.1 - 2.3e-65 216.7 3.8 1.4e-10 41.2 0.0 6.9 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KEY73170.1 - 1.3e-27 96.5 0.7 6e-05 23.9 0.1 6.3 6 0 0 6 6 6 5 AMP-binding enzyme C-terminal domain Transferase PF02458.10 KEY73170.1 - 9.3e-15 53.9 0.1 0.0029 16.1 0.0 6.5 7 0 0 7 7 7 5 Transferase family HxxPF_rpt PF13745.1 KEY73170.1 - 7.5e-06 26.1 1.1 0.66 10.3 0.0 5.3 5 0 0 5 5 5 2 HxxPF-repeated domain AATase PF07247.7 KEY73170.1 - 0.0045 15.5 1.2 4.4 5.7 0.0 4.9 6 0 0 6 6 6 1 Alcohol acetyltransferase Glyco_hydro_18 PF00704.23 KEY73171.1 - 1.2e-62 212.4 0.0 1.7e-62 211.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KEY73171.1 - 2.3e-06 27.4 11.1 2.3e-06 27.4 7.7 3.2 3 0 0 3 3 3 2 Chitin recognition protein DNase_NucA_NucB PF14040.1 KEY73171.1 - 0.00046 20.3 0.2 0.0012 18.9 0.1 1.6 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB F-box-like PF12937.2 KEY73172.1 - 2.2e-06 27.2 0.2 7.9e-06 25.4 0.1 2.0 1 0 0 1 1 1 1 F-box-like Chitin_bind_1 PF00187.14 KEY73172.1 - 2.4e-05 24.2 67.3 0.0029 17.5 11.2 4.0 3 0 0 3 3 3 3 Chitin recognition protein F-box PF00646.28 KEY73172.1 - 0.056 13.1 0.2 0.3 10.7 0.0 2.2 2 0 0 2 2 2 0 F-box domain ACP_syn_III_C PF08541.5 KEY73172.1 - 0.072 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal LysM PF01476.15 KEY73173.1 - 2.7e-08 33.5 0.4 0.064 13.1 0.0 4.3 4 0 0 4 4 4 3 LysM domain CorA PF01544.13 KEY73174.1 - 4e-06 26.0 4.5 7.3e-06 25.2 3.1 1.3 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein HATPase_c PF02518.21 KEY73175.1 - 4.5e-21 74.6 0.1 1.1e-20 73.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KEY73175.1 - 1.6e-19 69.9 0.0 3.3e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KEY73175.1 - 5.8e-09 35.8 0.1 2e-08 34.1 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 KEY73175.1 - 0.007 16.4 0.0 0.027 14.6 0.0 2.1 2 0 0 2 2 2 1 GAF domain Glyco_hydro_61 PF03443.9 KEY73176.1 - 2.7e-81 272.5 0.0 3.1e-81 272.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HET PF06985.6 KEY73177.1 - 5e-31 107.7 2.4 1e-30 106.7 1.6 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.19 KEY73178.1 - 1.2e-71 241.7 32.1 1.3e-71 241.4 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY73178.1 - 3.4e-15 55.6 36.2 3.4e-15 55.6 25.1 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEY73178.1 - 0.049 12.0 32.3 0.28 9.5 3.3 3.3 2 2 1 3 3 3 0 MFS/sugar transport protein Zn_clus PF00172.13 KEY73179.1 - 9.3e-09 35.0 10.3 2e-08 33.9 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Oest_recep PF02159.10 KEY73179.1 - 0.059 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Oestrogen receptor Cellulase PF00150.13 KEY73180.1 - 1.5e-33 116.1 0.1 2.6e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Fungal_trans PF04082.13 KEY73180.1 - 1e-13 50.7 0.0 1.6e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY73180.1 - 2.8e-09 36.7 8.3 2.8e-09 36.7 5.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cellulase-like PF12876.2 KEY73180.1 - 0.0036 17.7 0.0 0.012 16.0 0.0 1.9 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 KEY73180.1 - 0.041 13.0 0.2 0.31 10.1 0.1 2.0 1 1 0 2 2 2 0 Beta-galactosidase Fungal_trans_2 PF11951.3 KEY73180.1 - 0.078 11.5 0.8 0.29 9.6 0.1 2.0 2 0 0 2 2 2 0 Fungal specific transcription factor domain adh_short_C2 PF13561.1 KEY73181.1 - 6.5e-27 94.8 0.0 8e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEY73181.1 - 3.2e-14 53.2 0.3 4.4e-14 52.7 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY73181.1 - 1.7e-05 24.5 0.3 2.9e-05 23.8 0.2 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KEY73181.1 - 0.00086 19.0 0.1 0.0023 17.7 0.1 1.7 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KEY73181.1 - 0.0045 17.0 1.6 0.008 16.1 1.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding DUF1485 PF07364.7 KEY73181.1 - 0.078 12.1 0.1 0.14 11.3 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1485) Fungal_trans PF04082.13 KEY73182.1 - 1.9e-27 95.7 0.1 2.9e-27 95.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY73182.1 - 7.7e-05 22.5 7.5 0.00016 21.5 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.10 KEY73183.1 - 1.5e-109 366.5 36.4 1.7e-109 366.3 25.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amido_AtzD_TrzD PF09663.5 KEY73184.1 - 7.7e-89 297.7 4.3 1e-83 280.9 2.1 2.2 2 0 0 2 2 2 2 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) Amidase PF01425.16 KEY73185.1 - 4.1e-74 250.0 0.2 4.7e-74 249.8 0.2 1.0 1 0 0 1 1 1 1 Amidase APH PF01636.18 KEY73186.1 - 1.4e-07 31.4 2.4 1.5e-05 24.8 0.4 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 KEY73186.1 - 5.2e-05 22.5 0.6 0.00032 19.9 0.3 2.2 1 1 1 2 2 2 1 Protein kinase domain Kdo PF06293.9 KEY73186.1 - 9.3e-05 21.5 0.0 0.00018 20.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KEY73186.1 - 0.0026 17.3 0.1 1 8.9 0.0 2.2 1 1 1 2 2 2 2 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 KEY73186.1 - 0.0031 16.3 0.0 0.0052 15.6 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.17 KEY73186.1 - 0.0054 16.0 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family WaaY PF06176.6 KEY73186.1 - 0.072 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Zn_clus PF00172.13 KEY73187.1 - 0.085 12.7 8.6 0.19 11.6 6.0 1.6 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY73188.1 - 1.3e-19 70.1 0.5 2.2e-19 69.3 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KEY73189.1 - 1.1e-30 106.5 23.8 1.8e-30 105.8 16.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily AAA_17 PF13207.1 KEY73189.1 - 7.5e-05 23.5 0.0 0.00017 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEY73189.1 - 0.0004 20.2 0.0 0.00077 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEY73189.1 - 0.0018 17.4 0.2 0.004 16.2 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin APS_kinase PF01583.15 KEY73189.1 - 0.0082 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.1 KEY73189.1 - 0.024 14.9 0.0 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KEY73189.1 - 0.062 13.2 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ArgK PF03308.11 KEY73189.1 - 0.067 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 ArgK protein KTI12 PF08433.5 KEY73189.1 - 0.11 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Iso_dh PF00180.15 KEY73190.1 - 1.4e-84 284.0 0.0 1.6e-84 283.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.7 KEY73190.1 - 0.085 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA RPAP3_C PF13877.1 KEY73190.1 - 0.15 12.0 0.0 0.42 10.6 0.0 1.7 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 Glyco_hydro_3 PF00933.16 KEY73191.1 - 1.8e-88 296.4 0.0 2.5e-88 295.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY73191.1 - 1.2e-58 198.3 0.1 3.1e-58 196.9 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEY73191.1 - 9.7e-24 83.1 0.0 2.1e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain CBM_1 PF00734.13 KEY73191.1 - 3.6e-12 45.7 15.0 3.6e-12 45.7 10.4 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_43 PF04616.9 KEY73192.1 - 2.1e-53 181.2 3.4 2.4e-53 181.0 2.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KEY73192.1 - 0.024 14.0 0.1 0.032 13.5 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_61 PF03443.9 KEY73193.1 - 2.1e-67 227.1 0.0 2.9e-67 226.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_35 PF01301.14 KEY73194.1 - 1.9e-80 270.6 0.1 2.7e-79 266.8 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 KEY73194.1 - 1.6e-57 193.8 1.2 2.2e-57 193.3 0.2 1.7 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 KEY73194.1 - 1.4e-45 154.0 3.0 1.5e-25 89.5 0.8 2.5 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 KEY73194.1 - 7.5e-23 79.7 0.1 3.2e-22 77.7 0.0 2.1 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 CorA PF01544.13 KEY73195.1 - 4.5e-12 45.6 0.2 7.8e-12 44.8 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Sugar_tr PF00083.19 KEY73196.1 - 1.7e-76 257.6 13.9 2e-76 257.3 9.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY73196.1 - 5.4e-28 97.7 13.8 5.4e-28 97.7 9.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEY73196.1 - 0.00014 20.4 3.3 0.00014 20.4 2.3 3.0 2 2 0 2 2 2 1 MFS/sugar transport protein OATP PF03137.15 KEY73196.1 - 0.0061 14.6 0.2 0.01 13.9 0.2 1.3 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family ketoacyl-synt PF00109.21 KEY73198.1 - 4.2e-75 252.5 0.0 1.2e-74 251.0 0.0 1.8 2 0 0 2 2 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KEY73198.1 - 5.2e-54 182.6 0.5 1.3e-49 168.3 0.0 3.3 3 0 0 3 3 3 2 KR domain adh_short PF00106.20 KEY73198.1 - 4.2e-46 156.8 0.6 1.6e-40 138.7 0.0 3.6 3 0 0 3 3 3 2 short chain dehydrogenase Acyl_transf_1 PF00698.16 KEY73198.1 - 9e-39 133.6 0.0 2.1e-38 132.4 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 KEY73198.1 - 9.9e-37 126.2 0.0 2.1e-36 125.1 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein PS-DH PF14765.1 KEY73198.1 - 1.6e-34 119.4 0.8 1.7e-33 116.0 0.0 2.4 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KEY73198.1 - 1.3e-30 105.6 0.0 3.8e-30 104.1 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KEY73198.1 - 5.9e-17 61.9 0.0 1.6e-16 60.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY73198.1 - 4.8e-11 42.6 0.0 1.5e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Epimerase PF01370.16 KEY73198.1 - 7.3e-11 41.9 0.0 3.6e-07 29.8 0.0 2.9 3 1 0 3 3 2 2 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.7 KEY73198.1 - 1.9e-08 34.6 0.0 7.3e-08 32.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KEY73198.1 - 1.4e-06 27.4 0.0 3.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 KEY73198.1 - 1.6e-06 27.4 0.0 3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family 3Beta_HSD PF01073.14 KEY73198.1 - 6e-06 25.1 0.0 0.00055 18.7 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_31 PF13847.1 KEY73198.1 - 1.4e-05 24.7 0.0 3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY73198.1 - 3.3e-05 24.4 0.0 0.00021 21.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain ACP_syn_III PF08545.5 KEY73198.1 - 0.011 15.3 0.2 0.038 13.6 0.1 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III RrnaAD PF00398.15 KEY73198.1 - 0.016 14.2 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KEY73198.1 - 0.033 14.2 0.0 0.25 11.3 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 KEY73198.1 - 0.083 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain NmrA PF05368.8 KEY73198.1 - 0.11 11.7 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family Methyltransf_PK PF05891.7 KEY73198.1 - 0.26 10.5 0.0 0.56 9.4 0.0 1.5 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_28 PF02636.12 KEY73198.1 - 0.31 10.3 0.0 0.58 9.4 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NNMT_PNMT_TEMT PF01234.12 KEY73198.1 - 0.32 9.9 0.0 0.71 8.7 0.0 1.5 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family ADH_zinc_N PF00107.21 KEY73199.1 - 0.00014 21.3 0.1 0.00057 19.4 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY73199.1 - 0.00032 20.4 0.0 0.001 18.8 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 KEY73200.1 - 4.7e-17 62.4 0.1 6.6e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY73200.1 - 2.7e-08 33.6 0.1 4e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY73200.1 - 2.3e-06 27.2 0.1 2.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KEY73200.1 - 1.5e-05 24.8 0.0 2.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KEY73200.1 - 0.0046 16.9 0.1 0.011 15.7 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding FAD_binding_4 PF01565.18 KEY73201.1 - 4e-16 58.7 2.6 6.9e-16 57.9 1.2 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KEY73201.1 - 2.3e-09 36.9 2.7 5e-09 35.9 1.9 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KEY73201.1 - 0.034 13.2 0.2 0.052 12.6 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Sulfotransfer_3 PF13469.1 KEY73202.1 - 0.00023 22.1 1.2 0.00036 21.4 0.8 1.4 1 1 0 1 1 1 1 Sulfotransferase family GMC_oxred_C PF05199.8 KEY73203.1 - 2e-26 92.9 0.0 3.3e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KEY73204.1 - 3.9e-39 134.5 0.0 2.2e-29 102.5 0.0 2.0 1 1 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.19 KEY73204.1 - 1.2e-08 34.2 0.1 0.0012 17.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KEY73204.1 - 3.7e-07 29.3 0.6 2.6e-06 26.6 0.4 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY73204.1 - 8.1e-05 22.5 0.1 0.00021 21.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KEY73204.1 - 8.9e-05 21.5 0.1 0.00013 20.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KEY73204.1 - 0.0021 17.2 0.1 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KEY73204.1 - 0.0042 16.9 0.0 0.037 13.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEY73204.1 - 0.016 13.6 0.0 0.029 12.8 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 KEY73204.1 - 0.066 12.2 0.2 0.11 11.4 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 KEY73204.1 - 0.08 13.3 0.0 2.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEY73204.1 - 0.088 11.6 0.0 8.4 5.1 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 KEY73204.1 - 0.13 10.8 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase adh_short PF00106.20 KEY73205.1 - 1.1e-13 51.5 4.3 1.5e-13 50.9 3.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY73205.1 - 4.7e-07 29.8 0.1 8.2e-07 29.0 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KEY73205.1 - 8e-06 25.9 0.3 1.3e-05 25.2 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KEY73205.1 - 0.00052 19.7 0.7 0.00077 19.1 0.5 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 KEY73205.1 - 0.021 14.1 0.2 0.034 13.3 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Saccharop_dh PF03435.13 KEY73205.1 - 0.14 11.1 0.2 0.22 10.4 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Rhodanese PF00581.15 KEY73206.1 - 8.8e-20 71.1 0.0 7.3e-13 48.8 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain ADH_zinc_N PF00107.21 KEY73207.1 - 5e-14 51.9 0.0 9.3e-14 51.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY73207.1 - 4.6e-09 36.0 0.1 1.9e-08 34.0 0.1 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 KEY73208.1 - 1.8e-22 80.0 0.1 3.8e-22 78.9 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY73208.1 - 7.9e-09 35.6 0.0 9.4e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KEY73208.1 - 1.8e-07 30.5 0.0 0.00075 18.7 0.0 2.2 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) KR PF08659.5 KEY73208.1 - 1.4e-05 24.8 0.2 2.9e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KEY73208.1 - 0.00079 19.4 0.1 0.0015 18.5 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 KEY73208.1 - 0.096 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ApbA PF02558.11 KEY73208.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.20 KEY73209.1 - 1.1e-20 74.1 0.4 2.9e-20 72.8 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY73209.1 - 2e-09 37.5 0.1 3.2e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEY73209.1 - 0.00032 20.1 0.0 0.00083 18.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KEY73209.1 - 0.00064 19.4 0.2 0.0072 16.0 0.0 2.1 2 0 0 2 2 2 1 KR domain DFP PF04127.10 KEY73209.1 - 0.0095 15.5 0.1 0.024 14.2 0.0 1.5 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein THF_DHG_CYH_C PF02882.14 KEY73209.1 - 0.06 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 KEY73209.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding MFS_1 PF07690.11 KEY73210.1 - 6.8e-37 126.9 55.7 1.8e-36 125.5 36.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KEY73210.1 - 9.4e-15 53.8 23.0 9.2e-14 50.5 16.0 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 KEY73211.1 - 5.6e-07 28.6 0.1 9.8e-07 27.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY73211.1 - 0.00031 20.6 13.0 0.00071 19.4 9.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KEY73212.1 - 5.3e-63 213.1 0.0 8.1e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.11 KEY73213.1 - 5e-13 48.9 0.1 7.3e-13 48.3 0.1 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Abhydrolase_6 PF12697.2 KEY73214.1 - 3e-12 46.9 0.0 3.9e-11 43.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY73214.1 - 3.6e-08 33.2 0.0 1e-06 28.4 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY73214.1 - 6.8e-07 29.1 0.0 4.7e-06 26.4 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.7 KEY73214.1 - 7.4e-05 21.5 0.0 0.00015 20.5 0.0 1.4 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 KEY73214.1 - 0.0057 15.9 0.0 0.051 12.7 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 KEY73214.1 - 0.0082 15.6 0.0 0.034 13.5 0.0 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) NAD_binding_10 PF13460.1 KEY73215.1 - 3.8e-06 27.0 0.2 4.3e-06 26.8 0.1 1.0 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KEY73215.1 - 0.00012 21.4 0.1 0.00012 21.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KEY73215.1 - 0.00014 21.3 0.0 0.00016 21.1 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KEY73215.1 - 0.00059 19.7 0.2 0.00063 19.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY73215.1 - 0.00069 19.3 0.1 0.00076 19.1 0.1 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KEY73215.1 - 0.0033 16.1 0.0 0.0039 15.9 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 KEY73215.1 - 0.0037 16.2 0.1 0.0039 16.2 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KEY73215.1 - 0.0074 16.3 0.0 0.0083 16.2 0.0 1.1 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.15 KEY73215.1 - 0.041 13.8 0.1 0.051 13.4 0.1 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 KEY73215.1 - 0.065 13.6 1.1 0.11 12.9 0.6 1.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 KEY73216.1 - 0.0034 16.6 0.1 0.004 16.4 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family p450 PF00067.17 KEY73217.1 - 4.6e-42 144.1 0.0 6.8e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KEY73218.1 - 7e-44 150.1 0.0 9.4e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3237 PF11578.3 KEY73219.1 - 2.1e-19 69.2 0.0 2.4e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) p450 PF00067.17 KEY73220.1 - 2.9e-69 233.7 0.0 3.5e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 KEY73221.1 - 1.5e-05 24.7 11.4 3.2e-05 23.7 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KEY73222.1 - 1.7e-66 224.6 0.0 2.2e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.10 KEY73223.1 - 1.7e-21 76.1 0.0 2.7e-12 45.8 0.0 3.0 3 0 0 3 3 3 3 Transferase family adh_short PF00106.20 KEY73224.1 - 1.4e-20 73.9 0.1 2.2e-20 73.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY73224.1 - 1.7e-06 27.9 0.0 2.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KEY73224.1 - 0.00066 19.7 0.2 0.0012 18.8 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 KEY73224.1 - 0.0044 16.7 0.0 0.012 15.3 0.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY73224.1 - 0.0094 15.4 0.0 0.014 14.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DAO PF01266.19 KEY73224.1 - 0.047 12.6 0.0 0.051 12.4 0.0 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KEY73224.1 - 0.048 13.2 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Eno-Rase_NADH_b PF12242.3 KEY73224.1 - 0.098 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 KEY73224.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 KEY73224.1 - 0.14 10.5 0.5 0.21 10.0 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 KEY73224.1 - 0.16 10.7 0.2 0.23 10.2 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_4 PF01565.18 KEY73225.1 - 3.7e-21 75.0 0.8 5.7e-21 74.4 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY73225.1 - 0.076 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like Terpene_synth_C PF03936.11 KEY73226.1 - 2.3e-25 89.3 0.1 2.9e-25 89.0 0.1 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain adh_short PF00106.20 KEY73227.1 - 1.6e-16 60.6 0.1 2.6e-16 59.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY73227.1 - 3.2e-06 26.9 0.0 5.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY73227.1 - 0.00023 20.9 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEY73227.1 - 0.001 18.5 0.0 0.0018 17.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Rubella_E2 PF05749.6 KEY73229.1 - 0.00099 18.4 2.1 0.0014 17.8 1.5 1.3 1 0 0 1 1 1 1 Rubella membrane glycoprotein E2 Tat PF00539.13 KEY73229.1 - 0.079 12.5 1.5 0.15 11.6 1.1 1.5 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) Dimer_Tnp_hAT PF05699.9 KEY73232.1 - 1.3e-15 56.7 0.1 4.3e-15 55.0 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SIMPL PF04402.9 KEY73235.1 - 3.6 7.3 7.1 4.8 6.9 4.9 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF541) APH PF01636.18 KEY73236.1 - 3.1e-09 36.9 0.0 1.9e-08 34.3 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KEY73236.1 - 0.0093 14.9 0.0 0.023 13.7 0.0 1.6 1 0 0 1 1 1 1 Fructosamine kinase SUR7 PF06687.7 KEY73237.1 - 3.8e-20 72.3 7.5 5e-20 71.9 5.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 KEY73237.1 - 0.095 12.5 7.4 0.015 15.1 2.6 1.5 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF3112 PF11309.3 KEY73237.1 - 0.15 11.8 9.3 0.031 14.0 3.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) DUF973 PF06157.6 KEY73237.1 - 0.33 9.8 13.7 0.52 9.2 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF4282 PF14110.1 KEY73237.1 - 5.5 7.2 12.8 15 5.8 8.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) bZIP_1 PF00170.16 KEY73238.1 - 0.0014 18.4 1.4 0.0026 17.6 0.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KEY73238.1 - 0.14 12.0 2.5 0.23 11.3 1.7 1.4 1 0 0 1 1 1 0 Basic region leucine zipper RunxI PF08504.6 KEY73238.1 - 0.2 12.1 3.2 0.52 10.7 0.1 2.5 3 0 0 3 3 3 0 Runx inhibition domain DDE_Tnp_1_7 PF13843.1 KEY73241.1 - 7.3e-12 44.9 0.0 1.2e-11 44.3 0.0 1.3 2 0 0 2 2 2 1 Transposase IS4 DUF148 PF02520.12 KEY73243.1 - 0.12 12.1 0.9 0.92 9.3 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function DUF148 NPV_P10 PF05531.7 KEY73243.1 - 0.55 10.5 5.7 10 6.4 0.0 3.3 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein RP1-2 PF12042.3 KEY73244.1 - 0.061 12.9 0.1 0.076 12.6 0.1 1.1 1 0 0 1 1 1 0 Tubuliform egg casing silk strands structural domain ICAT PF06384.6 KEY73245.1 - 0.13 12.0 0.8 0.41 10.4 0.3 2.0 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT DUF326 PF03860.11 KEY73245.1 - 2.3 8.1 4.6 3.7 7.5 0.3 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF326) IncA PF04156.9 KEY73245.1 - 5.9 6.4 14.7 2.1 7.8 0.1 3.1 2 1 0 2 2 2 0 IncA protein Ank_2 PF12796.2 KEY73246.1 - 1.4e-25 89.4 0.0 3.9e-09 36.7 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KEY73246.1 - 8.4e-21 72.6 0.2 0.00064 19.4 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 KEY73246.1 - 1.4e-20 72.8 1.0 0.0024 18.0 0.0 6.1 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEY73246.1 - 8.4e-17 61.2 0.2 1.1e-06 28.9 0.0 4.8 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY73246.1 - 2.5e-16 58.1 0.0 0.005 16.9 0.0 6.1 5 0 0 5 5 5 4 Ankyrin repeat Glycos_transf_3 PF00591.16 KEY73246.1 - 0.031 13.6 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family, a/b domain KAP_NTPase PF07693.9 KEY73246.1 - 0.047 12.6 0.0 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 KAP family P-loop domain HeLo PF14479.1 KEY73249.1 - 2.9e-35 121.9 0.0 4.9e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation zf-GRF PF06839.7 KEY73249.1 - 2.2e-05 24.2 1.2 2.2e-05 24.2 0.8 2.6 2 0 0 2 2 2 1 GRF zinc finger tRNA-synt_1f PF01921.13 KEY73249.1 - 0.069 11.8 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) Zn_Tnp_IS1595 PF12760.2 KEY73249.1 - 7.8 6.3 9.3 0.54 10.1 2.3 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain NPP1 PF05630.6 KEY73250.1 - 0.0025 17.5 0.3 4.1 7.0 0.1 3.5 1 1 2 3 3 3 2 Necrosis inducing protein (NPP1) FAD_binding_4 PF01565.18 KEY73253.1 - 1.5e-21 76.3 0.5 2.6e-21 75.5 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY73253.1 - 0.00012 21.8 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like ALO PF04030.9 KEY73253.1 - 0.02 14.4 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Cytokin-bind PF09265.5 KEY73253.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding VSP PF03302.8 KEY73257.1 - 1.4e-06 27.2 0.1 2.1e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.6 KEY73257.1 - 0.00012 21.6 0.3 0.00022 20.8 0.2 1.4 1 0 0 1 1 1 1 Podoplanin CD99L2 PF12301.3 KEY73257.1 - 0.0019 17.8 0.1 0.0031 17.2 0.1 1.4 1 0 0 1 1 1 1 CD99 antigen like protein 2 SKG6 PF08693.5 KEY73257.1 - 0.0065 15.7 3.1 0.012 14.8 2.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 KEY73257.1 - 0.025 14.0 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4366 PF14283.1 KEY73257.1 - 0.054 12.9 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Herpes_gE PF02480.11 KEY73257.1 - 0.099 10.8 0.0 0.25 9.5 0.0 1.6 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF1183 PF06682.7 KEY73257.1 - 0.13 11.8 6.0 0.34 10.4 3.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) PAP2_3 PF14378.1 KEY73258.1 - 7.1e-22 77.8 15.8 2.9e-19 69.3 3.1 3.0 3 1 0 3 3 3 2 PAP2 superfamily RabGAP-TBC PF00566.13 KEY73259.1 - 6.6e-34 117.2 1.9 6.6e-34 117.2 1.3 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 KEY73259.1 - 7.2e-08 31.9 0.0 0.00012 21.3 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF3548) Mso1_Sec1_bdg PF14475.1 KEY73260.1 - 2.5e-19 68.3 0.1 4.6e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 DUF2076 PF09849.4 KEY73260.1 - 0.0021 18.1 15.6 0.0021 18.1 10.8 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) Ribosomal_L28e PF01778.12 KEY73261.1 - 5.6e-34 117.0 2.6 1.2e-33 115.9 1.8 1.6 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 KEY73261.1 - 5.1e-21 74.6 21.4 5.1e-21 74.6 14.9 3.1 2 1 0 2 2 2 1 Mak16 protein C-terminal region TFIIF_alpha PF05793.7 KEY73261.1 - 0.03 12.7 18.1 0.034 12.5 12.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 KEY73261.1 - 1.4 6.7 26.8 1.9 6.3 18.6 1.1 1 0 0 1 1 1 0 Nop14-like family Vps55 PF04133.9 KEY73262.1 - 3e-46 156.0 6.6 3.3e-46 155.9 4.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 ABC2_membrane_3 PF12698.2 KEY73262.1 - 5.7 5.8 11.8 7.2 5.5 8.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Chorismate_bind PF00425.13 KEY73263.1 - 4.5e-69 232.6 0.0 1.4e-68 231.0 0.0 1.7 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 KEY73263.1 - 5.7e-24 84.6 0.0 1.4e-23 83.4 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 KEY73263.1 - 9.6e-14 51.5 0.0 4.8e-13 49.3 0.0 2.1 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 KEY73263.1 - 8.7e-06 25.3 0.0 4.1e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 TRAPPC9-Trs120 PF08626.6 KEY73264.1 - 1.3e-140 469.9 0.0 8.8e-140 467.2 0.0 2.2 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF4354 PF14263.1 KEY73264.1 - 0.23 11.1 0.1 27 4.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4354) adh_short PF00106.20 KEY73265.1 - 1.6e-09 37.9 0.0 4.7e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY73265.1 - 7.1e-07 29.2 0.0 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KEY73265.1 - 0.0093 15.1 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 KEY73265.1 - 0.036 13.7 0.0 0.11 12.0 0.0 1.9 1 1 0 1 1 1 0 KR domain Sugar_tr PF00083.19 KEY73266.1 - 1.5e-112 376.4 33.7 1.7e-112 376.2 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY73266.1 - 2.5e-19 69.2 35.1 2.5e-19 69.2 24.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2264 PF10022.4 KEY73268.1 - 1.5e-126 421.9 0.2 1.9e-126 421.5 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Surf_Ag_VNR PF07244.10 KEY73268.1 - 0.1 13.0 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Surface antigen variable number repeat DUF1777 PF08648.7 KEY73269.1 - 2.3e-25 89.3 94.3 2.1e-15 56.9 65.4 3.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1777) Glyco_hydro_63 PF03200.11 KEY73270.1 - 1.5e-228 760.6 0.0 2e-227 756.9 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 KEY73270.1 - 1.1e-05 24.3 0.0 2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Trehalase TrmE_N PF10396.4 KEY73272.1 - 5e-22 78.0 0.0 2.5e-21 75.7 0.0 2.2 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 KEY73272.1 - 6.6e-21 74.5 1.7 1.1e-20 73.8 0.1 2.2 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 KEY73272.1 - 2.3e-18 66.2 0.0 5.2e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEY73272.1 - 2.3e-05 23.9 0.0 0.00068 19.1 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KEY73272.1 - 2.3e-05 23.7 0.0 5e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KEY73272.1 - 0.00012 21.9 0.0 0.00038 20.3 0.0 2.0 1 1 0 1 1 1 1 Dynamin family cobW PF02492.14 KEY73272.1 - 0.0064 15.9 0.0 0.08 12.3 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KEY73272.1 - 0.014 14.6 0.0 0.029 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 KEY73272.1 - 0.016 15.7 0.0 0.06 13.8 0.0 2.1 2 0 0 2 2 1 0 Miro-like protein ABC_tran PF00005.22 KEY73272.1 - 0.022 15.0 0.0 0.053 13.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 KEY73272.1 - 0.12 11.7 0.0 0.51 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain AIG1 PF04548.11 KEY73272.1 - 0.15 11.1 0.3 0.47 9.5 0.0 1.9 2 0 0 2 2 2 0 AIG1 family Proteasome PF00227.21 KEY73273.1 - 9.8e-49 165.2 0.1 1.3e-48 164.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEY73273.1 - 6.8e-11 41.2 0.2 1.1e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Diacid_rec PF05651.8 KEY73273.1 - 0.059 12.7 0.1 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 Putative sugar diacid recognition Lysine_decarbox PF03641.9 KEY73274.1 - 2.3e-28 98.6 0.0 3.3e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase CLPTM1 PF05602.7 KEY73275.1 - 7.3e-149 496.1 0.0 9.7e-149 495.8 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) zf-Di19 PF05605.7 KEY73276.1 - 0.00025 21.0 0.2 0.72 10.0 0.0 3.2 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding Longin PF13774.1 KEY73277.1 - 4.3e-28 96.7 0.2 6.9e-28 96.0 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KEY73277.1 - 1.5e-14 53.3 0.0 3.9e-14 52.0 0.0 1.7 2 0 0 2 2 2 1 Synaptobrevin DUF1664 PF07889.7 KEY73277.1 - 0.0073 16.1 0.4 0.03 14.1 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) HSCB_C PF07743.8 KEY73277.1 - 0.041 14.3 1.0 3.7 8.0 0.1 2.3 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF4404 PF14357.1 KEY73277.1 - 0.12 12.7 1.0 16 6.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Sirohm_synth_C PF14823.1 KEY73277.1 - 0.55 9.5 4.8 4.9 6.5 0.4 2.8 2 1 1 3 3 3 0 Sirohaem biosynthesis protein C-terminal Elong_Iki1 PF10483.4 KEY73278.1 - 1.6e-81 273.7 0.0 1.9e-81 273.5 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 NACHT PF05729.7 KEY73278.1 - 0.0049 16.5 1.0 0.0085 15.7 0.3 1.7 1 1 1 2 2 2 1 NACHT domain ASXH PF13919.1 KEY73279.1 - 4.3e-22 78.3 0.0 6.2e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Asx homology domain FH2 PF02181.18 KEY73280.1 - 1.3e-81 274.4 6.2 3e-81 273.1 4.3 1.6 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_GBD PF06371.8 KEY73280.1 - 2.4e-64 216.1 0.1 7.3e-64 214.6 0.1 1.9 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 KEY73280.1 - 3.9e-55 186.3 2.2 1.8e-54 184.1 1.2 2.4 1 1 1 2 2 2 1 Diaphanous FH3 Domain VWA_CoxE PF05762.9 KEY73282.1 - 0.21 10.6 1.3 0.29 10.2 0.9 1.1 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Hus1 PF04005.7 KEY73283.1 - 5.8e-83 278.2 0.0 7.2e-83 277.8 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Sec16_C PF12931.2 KEY73284.1 - 1.2e-92 310.6 0.0 1.7e-92 310.2 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 KEY73284.1 - 5.7e-28 97.2 0.0 1.2e-27 96.2 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region E1-E2_ATPase PF00122.15 KEY73285.1 - 1.1e-15 57.2 0.0 2.7e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KEY73285.1 - 3.4e-15 57.0 0.0 1.6e-14 54.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEY73285.1 - 1.7e-09 38.1 0.1 7.8e-09 35.9 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEY73285.1 - 0.00059 19.7 0.0 0.0024 17.7 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEY73285.1 - 0.0011 18.5 0.0 0.0024 17.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Suc_Fer-like PF06999.7 KEY73286.1 - 2.4e-50 171.6 0.0 3.3e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like FAD_binding_6 PF00970.19 KEY73286.1 - 1.4e-07 31.5 0.0 3.2e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KEY73286.1 - 2.3e-05 24.8 0.0 0.00029 21.3 0.0 2.6 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KEY73286.1 - 0.018 14.9 0.0 0.066 13.1 0.0 1.9 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Aa_trans PF01490.13 KEY73287.1 - 9.2e-83 277.9 31.7 1.1e-82 277.7 22.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1056 PF06341.6 KEY73287.1 - 0.27 11.3 6.1 1.2 9.2 0.8 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1056) AA_permease PF00324.16 KEY73288.1 - 1.5e-59 201.6 29.4 1.8e-59 201.3 20.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEY73288.1 - 6.8e-21 74.3 34.1 1e-20 73.7 23.6 1.2 1 0 0 1 1 1 1 Amino acid permease cobW PF02492.14 KEY73289.1 - 2.6e-35 121.4 0.0 7.1e-35 120.0 0.0 1.6 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KEY73289.1 - 0.00084 19.0 0.0 0.0022 17.6 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 KEY73289.1 - 0.0049 16.6 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 KEY73289.1 - 0.012 15.1 0.0 0.027 14.0 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 KEY73289.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 KEY73289.1 - 0.039 13.4 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 KEY73289.1 - 0.081 12.4 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KEY73289.1 - 0.082 13.0 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KEY73289.1 - 0.083 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF463 PF04317.7 KEY73289.1 - 0.091 11.3 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 YcjX-like family, DUF463 NTPase_1 PF03266.10 KEY73289.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 NTPase PUL PF08324.6 KEY73291.1 - 1.3e-40 138.9 0.0 1.9e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 KEY73291.1 - 4.9e-34 117.2 0.0 7.4e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 KEY73291.1 - 2.9e-14 52.6 0.0 5.8e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.1 KEY73291.1 - 4.7e-05 22.9 0.0 8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.1 KEY73291.1 - 5e-05 23.4 0.0 0.00017 21.7 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain DUF2847 PF11009.3 KEY73291.1 - 0.0012 18.4 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) Thioredoxin_3 PF13192.1 KEY73291.1 - 0.0087 15.8 0.0 0.027 14.2 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin domain GDA1_CD39 PF01150.12 KEY73292.1 - 1.5e-99 333.4 0.0 2e-99 333.0 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family AAA_3 PF07726.6 KEY73293.1 - 0.042 13.4 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ras PF00071.17 KEY73294.1 - 3e-55 186.0 0.0 3.5e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEY73294.1 - 8.9e-19 68.1 0.0 1.3e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEY73294.1 - 1.1e-13 50.7 0.0 1.3e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KEY73294.1 - 1.2e-07 31.6 0.0 1.7e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KEY73294.1 - 1.8e-06 27.2 0.0 2.2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KEY73294.1 - 2.8e-06 26.8 0.0 5.5e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KEY73294.1 - 0.00061 19.9 0.0 0.0013 18.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KEY73294.1 - 0.001 18.2 0.1 0.0019 17.3 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 KEY73294.1 - 0.0014 18.2 0.1 0.069 12.6 0.0 2.3 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 KEY73294.1 - 0.0016 18.4 0.1 0.0049 16.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 KEY73294.1 - 0.0018 17.9 0.0 0.0061 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) SRPRB PF09439.5 KEY73294.1 - 0.0024 17.1 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 KEY73294.1 - 0.004 16.7 0.1 0.0077 15.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KEY73294.1 - 0.0049 16.6 0.2 0.0097 15.6 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase PduV-EutP PF10662.4 KEY73294.1 - 0.0076 15.7 0.0 0.1 12.1 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 KEY73294.1 - 0.008 15.6 0.2 0.017 14.5 0.1 1.5 1 1 0 1 1 1 1 AAA-like domain cobW PF02492.14 KEY73294.1 - 0.012 15.0 0.0 0.065 12.6 0.0 1.9 1 1 2 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 KEY73294.1 - 0.013 14.4 0.0 0.032 13.2 0.0 1.7 2 0 0 2 2 2 0 Septin NTPase_1 PF03266.10 KEY73294.1 - 0.021 14.5 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 NTPase MobB PF03205.9 KEY73294.1 - 0.022 14.4 0.1 0.056 13.1 0.0 1.7 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 KEY73294.1 - 0.061 12.5 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B RNA_helicase PF00910.17 KEY73294.1 - 0.07 13.3 0.0 0.42 10.8 0.0 2.0 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 KEY73294.1 - 0.086 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 KEY73294.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Acyl-CoA_dh_1 PF00441.19 KEY73295.1 - 9.8e-29 100.3 0.4 1.7e-28 99.6 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KEY73295.1 - 1.1e-14 53.6 0.0 2.3e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KEY73295.1 - 2.1e-13 50.6 0.2 4.4e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KEY73295.1 - 3.4e-12 46.9 0.1 7.2e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Spo12 PF05032.7 KEY73296.1 - 2e-13 49.7 1.1 2e-13 49.7 0.8 1.6 2 0 0 2 2 2 1 Spo12 family MMR_HSR1 PF01926.18 KEY73297.1 - 9.2e-20 70.7 0.1 2.6e-19 69.3 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 KEY73297.1 - 1e-17 63.6 0.2 2.4e-17 62.5 0.0 1.7 2 0 0 2 2 2 1 TGS domain FeoB_N PF02421.13 KEY73297.1 - 1.2e-12 47.4 0.0 1.8e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KEY73297.1 - 1.5e-05 24.9 0.3 0.015 15.1 0.0 2.6 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 KEY73297.1 - 0.0012 19.3 0.0 0.003 18.0 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 KEY73297.1 - 0.046 12.4 0.1 0.11 11.2 0.1 1.6 1 0 0 1 1 1 0 ArgK protein MCM PF00493.18 KEY73297.1 - 0.055 12.2 0.0 0.12 11.1 0.0 1.5 1 0 0 1 1 1 0 MCM2/3/5 family AAA_18 PF13238.1 KEY73297.1 - 0.31 11.3 3.4 8.8 6.6 2.4 2.6 1 1 0 1 1 1 0 AAA domain UreF PF01730.11 KEY73298.1 - 1.8e-14 54.0 0.0 3.3e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 UreF Cut12 PF11500.3 KEY73299.1 - 1.4e-38 131.9 11.5 1.4e-38 131.9 8.0 4.2 2 1 3 5 5 5 1 Spindle pole body formation-associated protein Tup_N PF08581.5 KEY73299.1 - 0.56 10.4 17.1 6.9 6.9 0.5 3.9 2 1 1 3 3 3 0 Tup N-terminal Pkinase PF00069.20 KEY73300.1 - 1.8e-72 243.5 0.0 2e-36 125.5 0.0 4.1 3 1 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.2 KEY73300.1 - 1.3e-70 237.6 2.8 1.3e-70 237.6 1.9 2.6 2 1 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.12 KEY73300.1 - 1.3e-46 158.7 0.0 1.2e-19 70.4 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 KEY73300.1 - 1.3e-18 67.0 0.0 1.3e-18 67.0 0.0 3.0 4 0 0 4 4 4 1 Histidyl-tRNA synthetase RWD PF05773.17 KEY73300.1 - 3.8e-14 52.5 0.0 1.3e-13 50.7 0.0 2.0 1 0 0 1 1 1 1 RWD domain APH PF01636.18 KEY73300.1 - 0.00017 21.3 1.8 0.56 9.9 0.0 3.1 3 0 0 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KEY73300.1 - 0.034 12.9 0.2 4.4 5.9 0.1 2.2 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase UQ_con PF00179.21 KEY73301.1 - 2.3e-33 114.5 0.0 3.2e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KEY73301.1 - 0.024 14.5 0.5 0.075 12.9 0.3 1.6 1 1 0 1 1 1 0 RWD domain Sporozoite_P67 PF05642.6 KEY73301.1 - 0.57 7.9 6.0 0.68 7.7 4.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nucleoplasmin PF03066.10 KEY73301.1 - 1.7 8.1 9.3 2.5 7.6 6.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin DnaJ PF00226.26 KEY73303.1 - 3.6e-26 90.6 3.5 5.9e-26 90.0 2.4 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KEY73303.1 - 1.8e-22 78.9 3.1 6.4e-21 74.0 0.1 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain HAD_2 PF13419.1 KEY73304.1 - 1.8e-20 73.8 0.0 2.9e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEY73304.1 - 1.3e-08 35.4 1.1 8.2e-08 32.9 0.2 2.4 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEY73304.1 - 1.2e-07 31.3 0.1 2.2e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.13 KEY73304.1 - 2.7e-07 30.3 0.0 4.3e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase_6 PF13344.1 KEY73304.1 - 0.013 15.3 0.0 0.84 9.5 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase UDPG_MGDP_dh_C PF03720.10 KEY73304.1 - 0.088 12.9 0.0 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Init_tRNA_PT PF04179.7 KEY73305.1 - 5.4e-135 450.7 0.0 1e-134 449.8 0.0 1.4 1 1 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase GFO_IDH_MocA PF01408.17 KEY73305.1 - 5.9e-10 39.7 0.6 1.5e-09 38.4 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold MFS_1 PF07690.11 KEY73306.1 - 2.2e-38 131.8 45.6 2.2e-38 131.8 31.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DHDPS PF00701.17 KEY73306.1 - 8e-35 119.8 0.0 1.2e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Sugar_tr PF00083.19 KEY73306.1 - 1e-18 67.2 4.9 1e-18 67.2 3.4 3.3 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KEY73306.1 - 0.00013 20.3 15.9 0.00014 20.2 10.3 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MutL PF13941.1 KEY73306.1 - 0.066 11.5 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 MutL protein MARVEL PF01284.18 KEY73307.1 - 0.0003 20.6 11.3 0.00047 19.9 7.9 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF4281 PF14108.1 KEY73307.1 - 0.0008 19.5 1.3 0.0013 18.7 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) DUF4481 PF14800.1 KEY73307.1 - 1.5 7.6 3.7 0.42 9.4 0.7 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4481) DUF1183 PF06682.7 KEY73307.1 - 5 6.6 9.9 15 5.0 4.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) Nop16 PF09420.5 KEY73308.1 - 7.8e-61 204.9 5.6 9.2e-48 162.4 0.8 2.0 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 Nsp1_C PF05064.8 KEY73308.1 - 0.016 14.8 0.1 0.038 13.6 0.1 1.7 1 1 0 1 1 1 0 Nsp1-like C-terminal region Spt5_N PF11942.3 KEY73308.1 - 4.9 7.8 8.9 29 5.3 6.2 2.2 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DAO PF01266.19 KEY73309.1 - 2.2e-54 184.7 0.8 3e-54 184.2 0.6 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY73309.1 - 0.0012 18.8 0.1 0.0028 17.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KEY73309.1 - 0.0042 17.4 0.2 1.8 9.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 KEY73309.1 - 0.015 14.4 0.1 0.83 8.7 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Mqo PF06039.10 KEY73309.1 - 0.11 10.6 0.1 1 7.4 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) GSHPx PF00255.14 KEY73310.1 - 2.3e-40 136.3 0.1 2.8e-40 136.0 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.5 KEY73310.1 - 8.6e-05 22.1 0.1 0.00011 21.8 0.1 1.4 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KEY73310.1 - 8.6e-05 22.2 0.2 0.00014 21.5 0.1 1.5 1 1 0 1 1 1 1 AhpC/TSA family DUF4174 PF13778.1 KEY73310.1 - 0.034 14.2 0.0 0.082 12.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4174) Fungal_trans_2 PF11951.3 KEY73312.1 - 1.4e-47 162.1 7.4 1.7e-46 158.5 5.2 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY73312.1 - 3.8e-07 29.9 7.3 8.5e-07 28.7 5.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GATase_4 PF13230.1 KEY73314.1 - 6e-17 61.2 0.1 6.5e-14 51.2 0.0 2.1 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KEY73314.1 - 4.7e-10 39.5 0.0 8.7e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KEY73314.1 - 1.5e-06 27.1 0.0 0.00012 20.9 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferases class-II WD40 PF00400.27 KEY73315.1 - 5.7e-13 48.2 8.9 0.014 15.2 0.0 6.9 7 1 0 7 7 7 5 WD domain, G-beta repeat DUF2415 PF10313.4 KEY73315.1 - 0.011 15.3 0.0 6.5 6.5 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Heme_oxygenase PF01126.15 KEY73316.1 - 9.4e-10 38.3 0.0 8.5e-09 35.2 0.0 2.1 2 0 0 2 2 2 1 Heme oxygenase TFIIF_alpha PF05793.7 KEY73316.1 - 3.7 5.8 4.5 6.4 5.0 3.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) EamA PF00892.15 KEY73317.1 - 2.7e-08 33.9 29.7 4.9e-07 29.8 1.4 2.9 3 0 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 KEY73317.1 - 1.1e-06 27.7 6.3 1.1e-06 27.7 4.3 1.5 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 KEY73317.1 - 3.8e-06 27.0 3.6 3.8e-06 27.0 2.5 3.1 3 1 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 KEY73317.1 - 5.2e-05 22.9 20.8 0.00021 20.9 0.4 3.1 3 0 0 3 3 3 2 Triose-phosphate Transporter family UAA PF08449.6 KEY73317.1 - 0.00021 20.3 10.9 0.00021 20.3 7.5 1.7 2 0 0 2 2 2 1 UAA transporter family DUF3955 PF13127.1 KEY73317.1 - 0.056 12.9 0.1 0.056 12.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3955) SR-25 PF10500.4 KEY73317.1 - 3.9 6.8 7.9 5.7 6.3 5.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NMT1 PF09084.6 KEY73318.1 - 0.0018 17.9 0.0 0.0068 16.0 0.0 1.8 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 KEY73318.1 - 0.002 17.4 0.0 0.019 14.2 0.0 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Cytochrom_CIII PF02085.11 KEY73319.1 - 0.033 14.2 0.9 0.045 13.8 0.6 1.2 1 0 0 1 1 1 0 Class III cytochrome C family MFS_1 PF07690.11 KEY73320.1 - 4.6e-35 120.9 63.6 9.3e-30 103.5 24.4 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily ATG22 PF11700.3 KEY73320.1 - 0.00083 17.9 13.1 0.00083 17.9 9.1 2.1 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like CAF1A PF12253.3 KEY73322.1 - 4.7e-22 77.9 2.7 4.7e-22 77.9 1.9 2.6 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 KEY73322.1 - 7e-14 51.7 38.2 1.4e-13 50.7 26.5 1.5 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal HlyD PF00529.15 KEY73322.1 - 0.035 13.4 24.0 0.056 12.7 16.6 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Borrelia_P83 PF05262.6 KEY73322.1 - 1.7 6.8 27.7 2.4 6.3 19.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF966 PF06136.8 KEY73322.1 - 7.2 5.9 24.5 13 5.1 17.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) EXS PF03124.9 KEY73324.1 - 1.3e-88 297.3 21.9 1.6e-88 297.0 15.2 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 KEY73324.1 - 2e-56 191.7 3.2 3e-56 191.2 0.0 2.2 2 0 0 2 2 2 1 SPX domain FUR PF01475.14 KEY73324.1 - 0.11 12.4 0.2 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Ferric uptake regulator family Peptidase_M18 PF02127.10 KEY73325.1 - 1.3e-126 422.6 0.0 1.5e-126 422.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) 2-Hacid_dh_C PF02826.14 KEY73329.1 - 4.8e-51 172.4 0.0 9.3e-51 171.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KEY73329.1 - 1.7e-15 56.6 0.0 2.6e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KEY73329.1 - 0.0036 17.1 0.0 0.0088 15.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AA_permease_2 PF13520.1 KEY73330.1 - 1.4e-62 211.6 42.7 1.8e-62 211.2 29.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEY73330.1 - 1.7e-30 105.7 26.9 1.7e-30 105.7 18.7 2.1 2 0 0 2 2 2 1 Amino acid permease DUF1754 PF08555.5 KEY73331.1 - 1.9e-13 50.8 8.9 2.8e-13 50.2 6.1 1.2 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) DUF605 PF04652.11 KEY73333.1 - 0.012 15.0 21.5 0.016 14.6 14.9 1.4 1 0 0 1 1 1 0 Vta1 like Totivirus_coat PF05518.6 KEY73333.1 - 2.6 5.7 13.9 3.8 5.2 9.6 1.2 1 0 0 1 1 1 0 Totivirus coat protein CTP_transf_1 PF01148.15 KEY73334.1 - 5.9e-06 26.1 8.0 5.9e-06 26.1 5.5 3.5 4 1 0 4 4 4 1 Cytidylyltransferase family ORC2 PF04084.9 KEY73335.1 - 2.6e-99 332.1 0.0 3.2e-99 331.8 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 OST-HTH PF12872.2 KEY73335.1 - 0.025 14.3 0.1 0.083 12.7 0.1 1.9 1 0 0 1 1 1 0 OST-HTH/LOTUS domain PGP_phosphatase PF09419.5 KEY73336.1 - 2.1e-64 215.9 0.0 2.4e-64 215.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 KEY73336.1 - 0.00031 20.3 0.1 0.00077 19.1 0.0 1.9 2 1 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 KEY73336.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Tim17 PF02466.14 KEY73338.1 - 1.4e-47 160.9 9.5 1.8e-47 160.5 6.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 KEY73338.1 - 0.095 12.6 1.1 0.47 10.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF543) TraW_N PF12477.3 KEY73338.1 - 2.8 7.9 0.0 2.8 7.9 0.0 3.4 4 0 0 4 4 4 0 Sex factor F TraW protein N terminal Glyco_hydro_16 PF00722.16 KEY73339.1 - 3e-10 39.7 0.1 4.8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 F-box PF00646.28 KEY73340.1 - 0.017 14.7 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 F-box domain MTTB PF06253.6 KEY73340.1 - 0.054 11.2 0.1 0.077 10.7 0.1 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) F-box-like PF12937.2 KEY73340.1 - 0.12 12.1 0.1 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 F-box-like DUF1660 PF07874.6 KEY73340.1 - 0.2 11.9 1.6 0.37 11.0 1.1 1.4 1 0 0 1 1 1 0 Prophage protein (DUF1660) Zn_clus PF00172.13 KEY73340.1 - 0.21 11.5 0.3 0.21 11.5 0.2 1.9 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.18 KEY73342.1 - 1.1e-17 64.5 0.6 1.6e-17 64.0 0.4 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KEY73342.1 - 0.00015 20.9 0.0 0.0037 16.4 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY73342.1 - 0.0008 18.5 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 KEY73342.1 - 0.006 16.1 0.0 0.0078 15.8 0.0 1.3 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KEY73342.1 - 0.13 11.5 0.0 0.83 8.9 0.0 1.9 2 0 0 2 2 2 0 RIO1 family CBM-like PF14683.1 KEY73344.1 - 7.7e-12 45.1 0.0 1.4e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 KEY73344.1 - 2.9e-08 33.7 0.1 1.1e-07 31.8 0.0 2.0 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II DUF2220 PF09983.4 KEY73344.1 - 0.035 13.2 0.1 0.083 12.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) SKIP_SNW PF02731.10 KEY73345.1 - 1.8e-62 209.4 8.2 1.8e-62 209.4 5.7 2.8 3 0 0 3 3 3 1 SKIP/SNW domain DUF4603 PF15376.1 KEY73345.1 - 0.53 7.4 16.5 0.79 6.8 11.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) EMP24_GP25L PF01105.19 KEY73346.1 - 9.2e-48 162.3 2.4 1e-47 162.1 1.7 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PhoD PF09423.5 KEY73347.1 - 2.6e-50 171.3 0.0 3.7e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase Rrp15p PF07890.7 KEY73348.1 - 2.3e-33 115.0 11.5 2.3e-33 115.0 7.9 2.3 2 1 0 2 2 2 1 Rrp15p KBP_C PF12309.3 KEY73348.1 - 0.46 9.3 5.9 0.73 8.7 4.1 1.3 1 0 0 1 1 1 0 KIF-1 binding protein C terminal Myc_N PF01056.13 KEY73348.1 - 0.64 9.1 15.7 1 8.4 10.9 1.4 1 1 0 1 1 1 0 Myc amino-terminal region DUF4611 PF15387.1 KEY73348.1 - 5.3 7.2 16.6 0.24 11.5 6.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) Selenoprotein_S PF06936.6 KEY73348.1 - 7.7 5.9 9.1 0.31 10.5 1.7 2.1 1 1 0 1 1 1 0 Selenoprotein S (SelS) Fer2 PF00111.22 KEY73349.1 - 3.9e-13 48.9 2.1 5.2e-13 48.5 1.4 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.22 KEY73350.1 - 2.8e-14 52.5 4.9 0.0011 18.6 0.0 5.4 5 0 0 5 5 5 5 Mitochondrial carrier protein COMPASS-Shg1 PF05205.7 KEY73351.1 - 3.6e-24 85.0 0.8 3.6e-24 85.0 0.5 2.1 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 TPT PF03151.11 KEY73352.1 - 5.4e-27 94.3 13.5 5.4e-27 94.3 9.3 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KEY73352.1 - 0.0006 19.8 11.6 0.0006 19.8 8.1 2.6 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 KEY73352.1 - 0.0018 17.2 19.0 0.019 13.8 13.2 2.0 1 1 0 1 1 1 1 UAA transporter family DUF914 PF06027.7 KEY73352.1 - 0.87 8.3 16.3 1.9 7.2 11.3 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) UCH PF00443.24 KEY73353.1 - 7.6e-34 117.0 0.0 1.4e-33 116.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEY73353.1 - 1.5e-06 27.9 0.0 3.3e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2079 PF09852.4 KEY73353.1 - 0.00034 19.4 0.2 0.00047 18.9 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2079) DUF2387 PF09526.5 KEY73353.1 - 0.16 11.8 0.6 13 5.8 0.0 2.8 3 0 0 3 3 3 0 Probable metal-binding protein (DUF2387) TauD PF02668.11 KEY73354.1 - 1.5e-43 149.3 0.0 2e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 KEY73354.1 - 0.063 13.8 0.1 0.26 11.8 0.0 1.9 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily adh_short_C2 PF13561.1 KEY73355.1 - 6e-27 94.9 0.3 7.8e-27 94.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEY73355.1 - 7.2e-22 78.0 0.8 1.3e-21 77.2 0.5 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY73355.1 - 3.9e-08 33.1 0.5 8.7e-08 32.0 0.3 1.6 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KEY73355.1 - 0.0087 15.7 0.4 0.0087 15.7 0.3 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KEY73355.1 - 0.023 13.8 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.16 KEY73355.1 - 0.065 12.6 0.3 0.22 10.9 0.2 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 KEY73355.1 - 0.14 12.6 1.3 0.27 11.6 0.9 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Metallophos PF00149.23 KEY73356.1 - 2.1e-41 141.5 1.0 3.3e-41 140.8 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HA2 PF04408.18 KEY73358.1 - 4.6e-19 68.3 0.0 1.6e-18 66.5 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KEY73358.1 - 1.8e-13 50.1 0.0 5.5e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KEY73358.1 - 2.8e-13 49.6 0.0 6.7e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KEY73358.1 - 5.7e-09 35.6 0.1 1.7e-07 30.8 0.0 2.8 2 1 1 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEY73358.1 - 2.7e-05 24.3 0.0 7.6e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KEY73358.1 - 0.004 16.0 0.0 0.0073 15.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 KEY73358.1 - 0.0068 16.2 4.3 0.42 10.4 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PhoH PF02562.11 KEY73358.1 - 0.019 14.2 0.0 0.049 12.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 KEY73358.1 - 0.073 12.1 0.0 0.2 10.7 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 KEY73358.1 - 0.075 12.7 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain HJURP_C PF12347.3 KEY73358.1 - 0.078 12.5 0.2 11 5.7 0.1 2.6 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat AAA_23 PF13476.1 KEY73358.1 - 0.15 12.3 0.0 0.15 12.3 0.0 2.9 3 0 0 3 3 1 0 AAA domain Med6 PF04934.9 KEY73359.1 - 1.3e-40 138.1 0.0 1.8e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component MMtag PF10159.4 KEY73360.1 - 5.5e-31 106.4 2.8 1.1e-30 105.5 1.9 1.5 1 0 0 1 1 1 1 Kinase phosphorylation protein DUF3684 PF12449.3 KEY73361.1 - 0 1406.6 0.0 0 1406.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 KEY73361.1 - 4.2e-05 23.2 0.0 0.00011 21.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3642 PF12182.3 KEY73361.1 - 0.023 15.1 0.0 0.068 13.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial lipoprotein Reprolysin_5 PF13688.1 KEY73361.1 - 0.025 14.5 0.1 0.06 13.2 0.1 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12 IF-2B PF01008.12 KEY73363.1 - 1.8e-46 158.4 0.1 4.3e-46 157.1 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF562 PF04763.7 KEY73363.1 - 0.1 11.8 0.0 0.3 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF562) ArgJ PF01960.13 KEY73364.1 - 1.5e-145 484.4 0.0 1.7e-145 484.3 0.0 1.0 1 0 0 1 1 1 1 ArgJ family IGPD PF00475.13 KEY73365.1 - 7e-59 197.8 0.1 8.8e-59 197.5 0.1 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase TPR_2 PF07719.12 KEY73366.1 - 3.2e-25 85.9 17.6 0.0054 16.5 0.1 10.7 11 0 0 11 11 11 7 Tetratricopeptide repeat Apc3 PF12895.2 KEY73366.1 - 8.3e-24 83.5 22.0 2.8e-22 78.6 0.9 6.1 4 2 3 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 KEY73366.1 - 1e-22 79.5 8.1 2e-07 30.5 0.0 8.1 6 2 4 10 10 9 8 TPR repeat TPR_1 PF00515.23 KEY73366.1 - 1.2e-22 78.5 12.4 0.00069 19.1 0.1 9.8 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 KEY73366.1 - 1.9e-20 72.9 20.4 0.00091 19.5 0.1 8.3 5 3 3 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 KEY73366.1 - 1.7e-17 63.0 22.3 0.00034 20.4 0.0 8.5 6 2 1 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 KEY73366.1 - 7.6e-16 56.6 3.7 0.01 15.5 0.0 9.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEY73366.1 - 7.1e-14 51.0 23.5 0.05 14.2 0.2 10.5 4 3 7 11 11 11 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEY73366.1 - 6.2e-13 49.0 26.6 2.2e-05 25.0 0.0 7.7 5 3 2 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 KEY73366.1 - 2.8e-07 30.5 9.4 3.7 8.2 0.0 8.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEY73366.1 - 9.3e-07 28.1 15.7 8.2 6.4 0.0 8.8 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_10 PF13374.1 KEY73366.1 - 3e-05 23.7 11.9 1.5 8.8 0.1 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEY73366.1 - 0.00042 20.2 5.8 15 6.1 0.0 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_15 PF13429.1 KEY73366.1 - 0.00065 18.8 8.0 0.21 10.6 0.1 5.3 3 3 2 5 5 5 1 Tetratricopeptide repeat Rapsyn_N PF10579.4 KEY73366.1 - 0.01 15.5 1.4 1.3 8.9 0.0 4.1 3 1 1 4 4 4 0 Rapsyn N-terminal myristoylation and linker region TPR_4 PF07721.9 KEY73366.1 - 0.21 12.1 11.5 0.76 10.3 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 KEY73366.1 - 0.43 10.4 15.4 6.1 6.7 0.1 6.2 7 1 0 8 8 8 0 Tetratricopeptide repeat DUF1757 PF08560.5 KEY73367.1 - 0.0025 17.5 0.0 0.0034 17.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) AMP-binding PF00501.23 KEY73369.1 - 1.1e-46 159.0 0.0 1.6e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEY73369.1 - 0.00075 20.4 0.1 0.0016 19.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAT PF02259.18 KEY73370.1 - 3.3e-74 250.0 6.8 6.7e-74 248.9 4.7 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 KEY73370.1 - 9.7e-25 87.3 0.7 3.4e-24 85.5 0.1 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KEY73370.1 - 3.1e-08 32.8 1.6 5.4e-08 32.1 0.1 2.2 2 0 0 2 2 2 1 FATC domain AIG2 PF06094.7 KEY73371.1 - 2.6e-19 69.5 0.1 3.8e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family DUF3859 PF12975.2 KEY73371.1 - 0.044 13.4 0.1 0.12 12.1 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3859) Chitin_bind_3 PF03067.10 KEY73372.1 - 1.1e-06 29.0 0.0 2.1e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Chitin binding domain Glyco_hydro_61 PF03443.9 KEY73372.1 - 1.9e-05 24.6 0.1 3.4e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ribosomal_60s PF00428.14 KEY73372.1 - 6.7 7.1 18.9 1.7e+03 -0.6 13.1 2.6 1 1 0 1 1 1 0 60s Acidic ribosomal protein SMI1_KNR4 PF09346.5 KEY73373.1 - 4.1e-34 117.3 0.0 6.4e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Sec8_exocyst PF04048.9 KEY73374.1 - 7.7e-49 164.9 1.2 7.7e-49 164.9 0.8 1.8 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 KEY73374.1 - 6.3e-11 41.7 1.2 1.1e-10 40.8 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Phage_GP20 PF06810.6 KEY73374.1 - 0.0065 15.9 0.8 0.016 14.6 0.5 1.6 1 0 0 1 1 1 1 Phage minor structural protein GP20 Sec5 PF15469.1 KEY73374.1 - 0.012 15.3 0.3 0.029 14.1 0.2 1.6 1 0 0 1 1 1 0 Exocyst complex component Sec5 EHN PF06441.7 KEY73375.1 - 9.4e-20 70.6 0.1 1.8e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Hid1 PF12722.2 KEY73376.1 - 2.4e-249 829.6 0.0 1.1e-248 827.4 0.0 1.8 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 KEY73376.1 - 3.9e-75 253.3 0.0 7.2e-75 252.4 0.0 1.4 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Pet127 PF08634.5 KEY73377.1 - 4.8e-111 370.3 1.2 7.1e-111 369.7 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Metallophos PF00149.23 KEY73378.1 - 7.6e-12 45.0 0.1 1.2e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3431 PF11913.3 KEY73378.1 - 0.022 14.2 0.4 0.052 12.9 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3431) Filaggrin PF03516.8 KEY73378.1 - 0.024 15.0 0.9 0.024 15.0 0.6 2.0 2 0 0 2 2 2 0 Filaggrin DDE_Tnp_1_7 PF13843.1 KEY73379.1 - 1.6e-07 30.7 0.0 1.8e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 ATP-synt_ab PF00006.20 KEY73380.1 - 1.7e-113 377.4 0.0 2.6e-113 376.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KEY73380.1 - 6.3e-19 68.5 0.5 1.2e-18 67.6 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KEY73380.1 - 0.00025 21.1 5.1 0.0055 16.8 2.6 3.0 1 1 1 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain GldM_N PF12081.3 KEY73380.1 - 0.048 13.1 0.3 0.16 11.4 0.2 1.8 1 0 0 1 1 1 0 GldM N-terminal domain TraA PF05513.6 KEY73380.1 - 0.1 12.7 0.5 0.23 11.6 0.3 1.5 1 0 0 1 1 1 0 TraA UPF0029 PF01205.14 KEY73381.1 - 2.5e-30 104.4 0.0 3.5e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 KEY73381.1 - 0.00051 19.9 0.0 0.0014 18.5 0.0 1.8 1 1 0 1 1 1 1 RWD domain ACT_7 PF13840.1 KEY73382.1 - 4.5e-16 58.1 0.2 4.2e-10 39.0 0.1 2.4 2 0 0 2 2 2 2 ACT domain DUF4032 PF13224.1 KEY73382.1 - 0.15 11.7 0.0 0.43 10.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4032) Methyltransf_32 PF13679.1 KEY73383.1 - 7.2e-22 77.5 0.0 1.3e-21 76.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY73383.1 - 0.0098 16.4 0.0 0.019 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Clavanin PF05452.6 KEY73383.1 - 0.08 12.9 0.3 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 Clavanin Syntaxin-6_N PF09177.6 KEY73384.1 - 1.6e-19 70.0 0.1 1.4e-18 67.0 0.0 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 KEY73384.1 - 1.3e-14 53.5 5.7 9.8e-14 50.7 3.0 2.5 2 0 0 2 2 2 1 SNARE domain DUF869 PF05911.6 KEY73384.1 - 0.028 12.6 0.0 0.037 12.2 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Filament PF00038.16 KEY73384.1 - 0.067 12.6 3.9 0.92 8.9 0.8 2.6 2 1 0 2 2 2 0 Intermediate filament protein GLE1 PF07817.8 KEY73385.1 - 1.1e-25 90.0 0.0 4.3e-25 88.1 0.0 1.9 1 1 0 1 1 1 1 GLE1-like protein IncA PF04156.9 KEY73385.1 - 0.078 12.5 12.6 0.24 10.9 0.0 2.2 2 0 0 2 2 2 0 IncA protein RNB PF00773.14 KEY73386.1 - 1.2e-78 264.7 0.0 3e-78 263.3 0.0 1.8 1 0 0 1 1 1 1 RNB domain DUF4239 PF14023.1 KEY73386.1 - 0.075 12.3 0.2 0.19 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Ferritin_2 PF13668.1 KEY73388.1 - 4.6e-38 130.2 0.2 7.4e-38 129.5 0.2 1.3 1 0 0 1 1 1 1 Ferritin-like domain MKT1_C PF12246.3 KEY73389.1 - 1.7e-61 207.3 0.0 2.4e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 KEY73389.1 - 3.2e-27 94.6 0.0 6.9e-27 93.6 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 KEY73389.1 - 0.001 19.2 0.0 0.0072 16.5 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 KEY73389.1 - 0.0012 18.8 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 XPG I-region DNA_ligase_A_M PF01068.16 KEY73390.1 - 6.7e-21 74.5 0.0 1.3e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KEY73390.1 - 3.2e-11 43.3 0.0 8.9e-11 41.9 0.0 1.7 2 0 0 2 2 2 1 DNA ligase N terminus DIOX_N PF14226.1 KEY73391.1 - 5.2e-23 81.7 0.0 8.6e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KEY73391.1 - 4.8e-16 58.8 0.0 1e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4048 PF13257.1 KEY73392.1 - 4.1e-09 36.4 9.7 4.7e-06 26.4 4.7 3.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4048) DUF4188 PF13826.1 KEY73393.1 - 9.6e-29 99.8 0.1 1.3e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 KEY73393.1 - 3.8e-06 26.1 0.1 5.2e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Haem-containing dehydratase COPIIcoated_ERV PF07970.7 KEY73394.1 - 0.0024 17.5 0.1 0.0033 17.0 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Glyco_hydro_76 PF03663.9 KEY73395.1 - 7.4e-148 492.8 7.2 9.3e-148 492.5 5.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KEY73395.1 - 0.044 12.8 9.2 1.5 7.8 0.2 3.2 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Dak1 PF02733.12 KEY73396.1 - 5.1e-115 383.4 6.9 5.1e-115 383.4 4.8 1.6 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.12 KEY73396.1 - 7.6e-44 149.4 0.0 1.5e-43 148.4 0.0 1.5 1 0 0 1 1 1 1 DAK2 domain LSM PF01423.17 KEY73397.1 - 7.1e-18 63.9 0.3 9.7e-18 63.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain Leu_zip PF15294.1 KEY73397.1 - 0.1 11.7 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Leucine zipper ECH_C PF13766.1 KEY73398.1 - 1.3e-30 105.9 0.0 3e-30 104.7 0.0 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KEY73398.1 - 1.3e-22 80.1 0.0 6.2e-22 77.9 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family GATA PF00320.22 KEY73399.1 - 0.00052 19.3 6.8 0.0053 16.0 0.7 2.7 2 0 0 2 2 2 2 GATA zinc finger NMO PF03060.10 KEY73400.1 - 1.9e-62 211.3 0.2 3.3e-62 210.5 0.1 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KEY73400.1 - 1.8e-10 40.2 0.0 2e-06 26.9 0.0 2.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KEY73400.1 - 0.0071 15.2 0.1 0.014 14.3 0.1 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 KEY73400.1 - 0.075 11.9 0.1 0.5 9.2 0.0 2.0 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 KEY73400.1 - 0.093 11.9 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF1902 PF08972.6 KEY73400.1 - 0.11 12.0 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) DUF561 PF04481.7 KEY73400.1 - 0.13 11.2 0.1 0.47 9.3 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF561) F-box-like PF12937.2 KEY73401.1 - 0.025 14.3 0.2 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 F-box-like p450 PF00067.17 KEY73402.1 - 2.7e-38 131.6 0.0 5.4e-37 127.4 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Med13_C PF06333.7 KEY73403.1 - 3.1e-100 335.6 0.0 5.5e-100 334.8 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 KEY73403.1 - 2.4e-23 82.4 0.0 4e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal Clr5 PF14420.1 KEY73404.1 - 6.6e-17 61.1 0.2 1.1e-16 60.4 0.2 1.4 1 0 0 1 1 1 1 Clr5 domain Exo_endo_phos_2 PF14529.1 KEY73405.1 - 2.4e-05 23.9 0.0 6.4e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF89 PF01937.14 KEY73405.1 - 0.03 13.1 1.6 0.037 12.8 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF89 Thioredoxin_8 PF13905.1 KEY73405.1 - 0.13 12.4 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin-like Lactonase PF10282.4 KEY73407.1 - 1.8e-10 40.4 0.0 8.4e-09 34.9 0.0 2.0 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller DDE_1 PF03184.14 KEY73410.1 - 1.8e-63 213.6 0.0 2.6e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 KEY73410.1 - 6.2e-13 48.0 0.0 1.4e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 KEY73410.1 - 7e-05 22.6 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_1 PF00126.22 KEY73410.1 - 0.0042 16.7 0.2 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family CENP-B_N PF04218.8 KEY73410.1 - 0.019 14.3 0.0 0.046 13.1 0.0 1.7 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_3 PF01381.17 KEY73410.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix HTH_37 PF13744.1 KEY73410.1 - 0.13 12.1 0.1 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Glyco_hydro_18 PF00704.23 KEY73411.1 - 4.6e-74 249.9 1.9 5.6e-74 249.6 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CAP59_mtransfer PF11735.3 KEY73412.1 - 1.8e-58 197.6 0.0 2.5e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 AIG2 PF06094.7 KEY73412.1 - 0.1 13.1 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 AIG2-like family HET PF06985.6 KEY73413.1 - 5.2e-35 120.6 0.6 8.1e-35 119.9 0.4 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_18 PF00704.23 KEY73414.1 - 2.1e-05 24.1 0.1 3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.23 KEY73415.1 - 1.2e-30 107.1 0.0 1.5e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ank_2 PF12796.2 KEY73417.1 - 2e-21 76.1 2.6 5.9e-06 26.5 0.2 6.1 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 KEY73417.1 - 1e-13 50.3 9.8 0.00017 21.2 0.0 6.2 7 0 0 7 7 7 3 Ankyrin repeat Pkinase PF00069.20 KEY73417.1 - 2.7e-13 49.6 0.0 5.6e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.1 KEY73417.1 - 3.9e-12 45.1 6.2 0.00049 20.0 0.0 6.1 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 KEY73417.1 - 3.6e-11 42.9 1.5 0.031 14.5 0.0 4.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEY73417.1 - 5.7e-10 39.4 5.8 0.091 13.3 0.0 6.2 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Halogen_Hydrol PF10112.4 KEY73418.1 - 0.078 12.3 0.1 0.26 10.6 0.0 1.9 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein RibD_C PF01872.12 KEY73419.1 - 2.1e-17 63.3 0.0 1.3e-16 60.8 0.0 1.8 1 1 0 1 1 1 1 RibD C-terminal domain DHFR_1 PF00186.14 KEY73419.1 - 2.5e-06 27.1 0.0 3.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Dihydrofolate reductase Phage_capsid PF05065.8 KEY73419.1 - 0.09 11.9 0.0 0.31 10.2 0.0 1.6 1 1 0 2 2 2 0 Phage capsid family Zn_clus PF00172.13 KEY73420.1 - 1.6e-08 34.3 12.2 2.8e-08 33.5 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY73420.1 - 0.00024 20.0 0.2 0.001 18.0 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain FANCI_S1-cap PF14674.1 KEY73420.1 - 0.097 12.7 0.7 1.7 8.7 0.2 2.4 2 0 0 2 2 2 0 FANCI solenoid 1 cap DUF2638 PF10937.3 KEY73420.1 - 0.22 12.5 1.3 0.62 11.0 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2638) FAD_binding_3 PF01494.14 KEY73421.1 - 3.7e-18 65.7 0.0 2.4e-17 63.0 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEY73421.1 - 3.6e-09 35.9 0.1 0.00079 18.4 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEY73421.1 - 3.5e-07 30.5 0.3 3.2e-06 27.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEY73421.1 - 0.0014 18.5 0.0 0.003 17.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY73421.1 - 0.0071 16.3 0.0 0.021 14.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEY73421.1 - 0.038 12.8 0.0 0.055 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 KEY73421.1 - 0.048 13.0 0.0 0.34 10.3 0.0 2.0 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA TPR_12 PF13424.1 KEY73422.1 - 4.3e-18 65.0 6.3 3.2e-05 23.7 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 KEY73422.1 - 1.7e-07 30.9 7.6 0.0045 16.8 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat NACHT PF05729.7 KEY73422.1 - 9.4e-07 28.6 0.0 3.5e-06 26.7 0.0 2.0 1 0 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.2 KEY73422.1 - 7.2e-06 26.0 0.0 2.1e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.1 KEY73422.1 - 0.00023 21.2 0.0 0.0021 18.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KEY73422.1 - 0.00073 18.4 0.0 0.0031 16.4 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain TPR_1 PF00515.23 KEY73422.1 - 0.00082 18.8 2.9 0.005 16.3 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Abhydrolase_5 PF12695.2 KEY73422.1 - 0.0012 18.5 0.1 0.0092 15.7 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Cutinase PF01083.17 KEY73422.1 - 0.0014 18.3 0.0 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 Cutinase TPR_2 PF07719.12 KEY73422.1 - 0.0017 18.1 4.0 0.09 12.7 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat PGAP1 PF07819.8 KEY73422.1 - 0.0017 17.9 0.1 0.0033 17.0 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein AAA_25 PF13481.1 KEY73422.1 - 0.0022 17.4 0.0 0.0086 15.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 KEY73422.1 - 0.0064 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein TPR_7 PF13176.1 KEY73422.1 - 0.02 14.6 0.1 0.14 12.0 0.1 2.5 1 0 0 1 1 1 0 Tetratricopeptide repeat KaiC PF06745.8 KEY73422.1 - 0.025 13.7 0.0 0.069 12.2 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 KEY73422.1 - 0.07 12.8 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain DUF676 PF05057.9 KEY73422.1 - 0.077 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) TPR_14 PF13428.1 KEY73422.1 - 0.091 13.4 8.0 1.9 9.3 0.0 5.6 2 1 3 5 5 4 0 Tetratricopeptide repeat HTH_OrfB_IS605 PF12323.3 KEY73422.1 - 0.13 11.6 0.0 0.39 10.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain TPR_11 PF13414.1 KEY73422.1 - 0.15 11.7 4.0 1 9.0 0.1 3.4 3 1 0 3 3 2 0 TPR repeat TPR_16 PF13432.1 KEY73422.1 - 0.4 11.4 8.7 12 6.7 0.1 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.2 KEY73424.1 - 1.1e-38 131.4 20.0 1.3e-08 35.0 0.0 10.3 4 3 3 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.25 KEY73424.1 - 5.4e-18 63.8 21.9 0.00042 19.9 0.0 14.1 17 0 0 17 17 17 5 Ankyrin repeat Ank_3 PF13606.1 KEY73424.1 - 1.3e-15 55.9 14.8 0.11 12.8 0.0 14.7 14 2 1 16 16 16 3 Ankyrin repeat Ank_4 PF13637.1 KEY73424.1 - 1.1e-12 48.1 14.2 2.6e-05 24.6 0.0 10.5 11 2 2 13 13 13 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY73424.1 - 1.2e-06 28.5 17.9 0.01 16.0 0.0 8.1 7 2 2 9 9 9 3 Ankyrin repeats (many copies) Fungal_trans_2 PF11951.3 KEY73426.1 - 0.4 9.2 10.2 0.25 9.8 3.5 2.6 2 1 0 2 2 2 0 Fungal specific transcription factor domain Aldo_ket_red PF00248.16 KEY73427.1 - 3.1e-75 252.6 0.0 3.6e-75 252.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_61 PF03443.9 KEY73428.1 - 2.5e-42 145.1 0.0 3.3e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 p450 PF00067.17 KEY73429.1 - 4.7e-68 229.7 0.0 5.3e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KEY73430.1 - 2.4e-36 125.1 22.7 2.4e-36 125.1 15.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KEY73431.1 - 7e-25 87.3 0.0 1.1e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY73431.1 - 8.4e-07 28.7 10.8 1.5e-06 28.0 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydantoinase_B PF02538.9 KEY73432.1 - 6e-184 612.1 0.0 8.1e-184 611.7 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KEY73432.1 - 1.1e-79 267.6 0.0 2.2e-79 266.6 0.0 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KEY73432.1 - 3e-55 186.4 0.1 1.2e-53 181.2 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region UBA_2 PF08587.6 KEY73432.1 - 0.057 13.6 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) RTA1 PF04479.8 KEY73433.1 - 9.3e-34 116.8 1.6 1.2e-33 116.5 1.1 1.1 1 0 0 1 1 1 1 RTA1 like protein NfeD PF01957.13 KEY73433.1 - 0.91 9.6 4.9 0.31 11.1 0.5 2.1 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding LHC PF00556.15 KEY73433.1 - 3 7.7 10.8 0.099 12.5 1.7 2.5 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit Pec_lyase_C PF00544.14 KEY73435.1 - 1.1e-35 122.9 9.5 2e-35 122.0 6.6 1.4 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KEY73435.1 - 0.00079 19.2 10.8 0.04 13.6 7.5 2.5 1 1 0 1 1 1 1 Right handed beta helix region COesterase PF00135.23 KEY73436.1 - 2.5e-87 293.7 0.0 2.9e-87 293.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEY73436.1 - 0.00052 19.6 0.1 0.0022 17.5 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEY73436.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ubiquitin_2 PF14560.1 KEY73438.1 - 0.14 12.3 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain Zn_clus PF00172.13 KEY73439.1 - 1e-09 38.0 9.5 1.7e-09 37.3 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY73439.1 - 4e-08 32.4 0.0 6.8e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 KEY73440.1 - 1.1e-86 291.1 21.0 1.4e-86 290.8 14.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY73440.1 - 3.4e-16 58.8 28.3 5.8e-13 48.2 15.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-amylase PF00128.19 KEY73441.1 - 2.8e-96 322.6 0.1 4.7e-96 321.8 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KEY73441.1 - 0.00021 20.3 0.0 0.00042 19.3 0.0 1.4 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Catalase PF00199.14 KEY73442.1 - 1.7e-60 204.7 0.0 1.9e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase PF00199.14 KEY73443.1 - 3.9e-26 91.6 0.2 5.6e-26 91.1 0.2 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KEY73443.1 - 1e-10 41.3 0.0 1.9e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF4410 PF14366.1 KEY73443.1 - 0.091 12.4 0.5 0.2 11.3 0.4 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4410) Catalase PF00199.14 KEY73444.1 - 5.2e-145 482.9 0.6 6.6e-145 482.6 0.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KEY73444.1 - 4.2e-11 42.5 0.0 8.8e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Peptidase_S8 PF00082.17 KEY73445.1 - 5e-40 137.4 13.5 7e-40 136.9 9.4 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KEY73445.1 - 1.4e-14 54.3 0.0 2.6e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 GMC_oxred_N PF00732.14 KEY73446.1 - 1.3e-57 195.2 0.0 1.7e-57 194.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY73446.1 - 1.8e-24 86.6 0.0 4.9e-24 85.2 0.0 1.8 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KEY73446.1 - 1e-06 27.9 0.2 0.033 13.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KEY73446.1 - 3.1e-06 26.3 0.3 0.00012 21.1 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEY73446.1 - 3.3e-06 26.2 0.1 5.7e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KEY73446.1 - 5.1e-05 23.2 0.0 0.00015 21.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KEY73446.1 - 0.0021 16.7 0.0 0.0034 16.0 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 KEY73446.1 - 0.0023 17.8 0.0 0.0061 16.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEY73446.1 - 0.0033 16.5 0.1 0.0074 15.4 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KEY73446.1 - 0.0088 15.1 1.3 0.51 9.3 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.22 KEY73446.1 - 0.02 15.3 0.0 0.082 13.3 0.0 2.1 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEY73446.1 - 0.024 14.3 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KEY73446.1 - 0.17 10.9 0.9 2.5 7.0 0.4 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase CorA PF01544.13 KEY73447.1 - 1.9e-08 33.7 0.2 2.3e-08 33.4 0.1 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein HemY_N PF07219.8 KEY73447.1 - 0.06 12.9 1.8 0.13 11.8 0.1 2.3 2 1 0 2 2 2 0 HemY protein N-terminus Na_Ca_ex PF01699.19 KEY73447.1 - 0.061 12.9 1.2 0.1 12.2 0.8 1.3 1 0 0 1 1 1 0 Sodium/calcium exchanger protein DUF1469 PF07332.6 KEY73447.1 - 0.097 12.3 3.4 0.15 11.7 1.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) TruD PF01142.13 KEY73449.1 - 0.069 11.8 0.1 0.083 11.5 0.0 1.2 1 0 0 1 1 1 0 tRNA pseudouridine synthase D (TruD) An_peroxidase PF03098.10 KEY73451.1 - 1.1e-92 311.1 0.0 2.7e-90 303.2 0.0 2.1 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KEY73451.1 - 2.5e-08 32.8 0.0 6.3e-06 24.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 AAA PF00004.24 KEY73453.1 - 3.3e-16 59.6 0.0 9.8e-16 58.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEY73453.1 - 0.0035 17.3 0.0 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 KEY73453.1 - 0.032 13.9 0.1 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KEY73453.1 - 0.04 13.6 0.4 0.32 10.7 0.1 2.3 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 KEY73453.1 - 0.082 13.0 0.2 0.36 10.9 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 KEY73453.1 - 0.18 12.6 4.3 0.21 12.3 0.2 3.3 3 1 0 3 3 3 0 AAA domain Phage_lysozyme PF00959.14 KEY73454.1 - 8.9e-17 61.3 0.0 1.2e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme HET PF06985.6 KEY73455.1 - 5.9e-26 91.2 0.0 1e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C2H2 PF00096.21 KEY73456.1 - 0.00054 20.1 1.0 0.00054 20.1 0.7 4.6 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY73456.1 - 0.0063 16.7 0.4 0.0063 16.7 0.3 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger MFS_1 PF07690.11 KEY73458.1 - 1.9e-39 135.4 40.8 1.9e-39 135.4 28.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY73458.1 - 4.5e-13 48.5 14.3 4.5e-13 48.5 9.9 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter HET PF06985.6 KEY73460.1 - 0.0002 21.5 0.0 0.00033 20.8 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 KEY73461.1 - 3.2e-16 59.6 0.4 5.3e-16 58.9 0.3 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY73461.1 - 3.3e-13 49.9 0.1 4e-13 49.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY73461.1 - 3.8e-07 29.9 0.0 5.8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Pkinase PF00069.20 KEY73463.1 - 3.1e-24 85.5 0.0 5.6e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY73463.1 - 2.4e-11 43.1 0.0 9.5e-11 41.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_43 PF04616.9 KEY73464.1 - 9.5e-105 349.7 1.7 1.5e-104 349.0 1.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KEY73464.1 - 0.026 13.9 0.2 0.074 12.3 0.1 1.6 1 1 1 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain COesterase PF00135.23 KEY73465.1 - 1.1e-87 294.9 0.0 1.4e-87 294.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEY73465.1 - 4e-08 33.0 0.1 1.3e-07 31.4 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEY73465.1 - 3.3e-06 26.4 0.3 5.9e-06 25.6 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KEY73465.1 - 0.0018 18.1 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY73465.1 - 0.0048 16.6 0.1 0.0079 15.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family FAD_binding_3 PF01494.14 KEY73467.1 - 5.1e-23 81.7 0.0 8e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KEY73467.1 - 5.6e-05 23.0 0.1 0.00015 21.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KEY73467.1 - 0.00043 19.4 0.1 0.092 11.7 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 KEY73467.1 - 0.0012 17.8 0.6 0.72 8.6 0.4 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEY73467.1 - 0.024 15.0 0.2 0.024 15.0 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEY73467.1 - 0.037 13.9 0.0 0.088 12.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY73467.1 - 0.04 12.8 0.1 2.9 6.7 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 KEY73467.1 - 0.12 11.9 0.1 0.84 9.1 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Amidohydro_4 PF13147.1 KEY73468.1 - 1.8e-21 77.4 0.0 2.3e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KEY73468.1 - 1.2e-11 44.2 0.1 2.8e-11 43.0 0.1 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KEY73468.1 - 7.3e-11 42.2 0.0 1.5e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 KEY73468.1 - 0.0048 16.1 0.0 0.21 10.7 0.0 2.4 3 0 0 3 3 3 1 Amidohydrolase family DUF2574 PF10836.3 KEY73469.1 - 0.063 12.9 0.5 0.18 11.5 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2574) Zn_clus PF00172.13 KEY73470.1 - 0.0012 18.6 8.0 0.0023 17.8 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 KEY73471.1 - 1.1e-69 234.4 0.0 1.4e-69 234.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ank_2 PF12796.2 KEY73474.1 - 2.3e-49 165.6 0.0 1.8e-14 53.8 0.2 6.2 3 2 3 6 6 6 4 Ankyrin repeats (3 copies) Ank PF00023.25 KEY73474.1 - 1.4e-44 147.7 3.4 6.1e-07 28.9 0.0 11.9 13 0 0 13 13 13 7 Ankyrin repeat Ank_5 PF13857.1 KEY73474.1 - 1.7e-32 110.7 6.9 1.2e-08 34.8 0.1 7.7 6 2 1 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEY73474.1 - 1.7e-31 108.0 5.7 1.5e-06 28.5 0.0 9.6 6 3 4 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY73474.1 - 4e-28 94.6 7.7 0.0025 17.9 0.0 13.3 14 0 0 14 14 14 5 Ankyrin repeat NACHT PF05729.7 KEY73474.1 - 0.00041 20.0 0.0 0.00081 19.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 KEY73474.1 - 0.0058 15.5 0.0 0.018 13.9 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.1 KEY73474.1 - 0.0065 16.6 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Cyt-b5 PF00173.23 KEY73475.1 - 9.2e-14 51.0 0.0 1.7e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 KEY73475.1 - 3.8e-13 49.4 14.2 3.8e-13 49.4 9.8 1.9 1 1 1 2 2 2 1 Fatty acid desaturase CMAS PF02353.15 KEY73476.1 - 9.6e-62 208.5 0.0 1.9e-61 207.5 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KEY73476.1 - 1.9e-10 40.6 0.0 3.7e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY73476.1 - 2.6e-09 37.4 0.0 5.1e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY73476.1 - 4e-08 33.8 0.0 7.2e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY73476.1 - 7e-08 32.2 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY73476.1 - 1.3e-06 28.8 0.0 2.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY73476.1 - 7.3e-06 26.2 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY73476.1 - 0.01 15.8 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KEY73476.1 - 0.012 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_PK PF05891.7 KEY73476.1 - 0.037 13.3 0.0 0.1 11.9 0.0 1.7 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase GCD14 PF08704.5 KEY73476.1 - 0.11 11.9 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit adh_short PF00106.20 KEY73477.1 - 7e-29 100.8 1.5 7.9e-29 100.7 1.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY73477.1 - 4.5e-18 65.9 0.3 5.4e-18 65.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY73477.1 - 1.6e-17 63.7 0.6 2.1e-17 63.3 0.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY73477.1 - 1.8e-09 37.3 0.6 2.6e-09 36.8 0.4 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KEY73477.1 - 8.8e-05 21.6 0.9 0.00012 21.1 0.5 1.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 KEY73477.1 - 0.0001 21.3 0.4 0.00015 20.7 0.3 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KEY73477.1 - 0.0028 17.6 0.6 0.005 16.8 0.4 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KEY73477.1 - 0.012 14.9 0.2 0.021 14.1 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family Eno-Rase_NADH_b PF12242.3 KEY73477.1 - 0.014 15.1 0.4 0.036 13.8 0.3 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3Beta_HSD PF01073.14 KEY73477.1 - 0.022 13.4 0.1 0.027 13.1 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family YjeF_N PF03853.10 KEY73477.1 - 0.055 13.0 0.1 0.088 12.4 0.1 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus 2-Hacid_dh_C PF02826.14 KEY73477.1 - 0.087 11.9 1.0 0.16 11.1 0.4 1.7 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Kp4 PF09044.5 KEY73477.1 - 0.12 12.1 1.2 0.18 11.5 0.3 1.7 2 0 0 2 2 2 0 Kp4 AdoHcyase_NAD PF00670.16 KEY73477.1 - 0.43 10.3 5.4 2.9 7.6 3.8 2.4 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Methyltransf_31 PF13847.1 KEY73478.1 - 5.4e-12 45.5 0.0 3.4e-11 42.9 0.0 2.1 2 1 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY73478.1 - 7.3e-12 45.2 0.0 1.1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY73478.1 - 1.4e-07 32.0 0.0 4.4e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY73478.1 - 5.2e-07 30.0 0.0 9.1e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY73478.1 - 4e-06 26.1 0.0 7.1e-06 25.2 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KEY73478.1 - 1.9e-05 24.6 0.0 3.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY73478.1 - 5.8e-05 23.4 0.0 0.00012 22.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY73478.1 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KEY73478.1 - 0.022 14.7 0.0 0.029 14.3 0.0 1.3 1 1 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 KEY73478.1 - 0.15 11.1 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ABC_membrane PF00664.18 KEY73479.1 - 5.5e-70 235.9 36.6 1.7e-42 145.7 4.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KEY73479.1 - 1.9e-65 219.2 0.1 2.2e-32 112.2 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 KEY73479.1 - 1.9e-13 50.1 0.1 0.0011 18.2 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEY73479.1 - 5.4e-12 46.2 0.1 0.00069 19.6 0.0 4.1 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KEY73479.1 - 1.2e-08 34.2 0.3 0.0055 16.2 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KEY73479.1 - 1.1e-07 32.6 0.1 0.034 14.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KEY73479.1 - 2e-07 30.8 2.4 0.0065 16.0 0.0 4.5 4 1 0 4 4 4 1 AAA domain Zeta_toxin PF06414.7 KEY73479.1 - 2.1e-07 30.2 0.0 0.0027 16.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin DUF258 PF03193.11 KEY73479.1 - 3.6e-07 29.4 1.5 0.00057 19.1 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KEY73479.1 - 4.8e-07 29.9 6.5 0.0012 18.8 0.1 3.1 2 2 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 KEY73479.1 - 5.2e-06 25.3 0.7 0.00025 19.7 0.0 3.0 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_23 PF13476.1 KEY73479.1 - 1.3e-05 25.6 0.1 0.031 14.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.15 KEY73479.1 - 1.6e-05 24.6 0.3 0.098 12.3 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_33 PF13671.1 KEY73479.1 - 4.6e-05 23.3 0.1 0.061 13.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 KEY73479.1 - 6.2e-05 23.1 1.4 0.55 10.3 0.0 3.9 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KEY73479.1 - 7.3e-05 22.2 1.2 0.45 9.8 0.0 3.5 4 0 0 4 4 3 2 AAA domain SbcCD_C PF13558.1 KEY73479.1 - 0.00025 20.9 1.6 0.99 9.3 0.0 3.4 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 KEY73479.1 - 0.00057 19.4 1.1 1.1 8.5 0.1 2.9 3 0 0 3 3 3 2 AAA-like domain AAA_18 PF13238.1 KEY73479.1 - 0.00064 20.0 0.2 0.56 10.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KEY73479.1 - 0.00079 19.3 0.1 1.3 8.9 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase DUF3987 PF13148.1 KEY73479.1 - 0.0074 14.8 0.0 2.1 6.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) ATP-synt_ab PF00006.20 KEY73479.1 - 0.0086 15.6 1.2 2.4 7.5 0.1 3.3 4 0 0 4 4 4 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 KEY73479.1 - 0.014 15.2 0.0 3.5 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KEY73479.1 - 0.026 14.7 1.5 23 5.1 0.1 4.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KEY73479.1 - 0.04 12.7 0.1 4.7 5.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.12 KEY73479.1 - 0.045 13.5 0.5 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_5 PF07728.9 KEY73479.1 - 0.051 13.2 0.1 7.8 6.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KEY73479.1 - 0.12 12.5 0.1 8.3 6.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase PRK PF00485.13 KEY73479.1 - 0.17 11.4 0.4 10 5.5 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Pec_lyase_C PF00544.14 KEY73480.1 - 2e-44 151.4 4.2 2.7e-44 151.0 2.9 1.1 1 0 0 1 1 1 1 Pectate lyase BIV_Env PF05858.7 KEY73480.1 - 0.12 10.3 0.1 0.16 9.8 0.0 1.2 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) Glyco_hydro_61 PF03443.9 KEY73481.1 - 7.8e-68 228.5 0.2 9.1e-68 228.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Big_3_4 PF13754.1 KEY73481.1 - 0.019 15.3 2.8 0.097 13.0 0.1 2.6 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Ras PF00071.17 KEY73482.1 - 1e-37 128.9 0.0 1.6e-37 128.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEY73482.1 - 7.9e-15 55.4 0.0 1.7e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 KEY73482.1 - 0.0015 17.7 0.2 0.0086 15.3 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.5 KEY73482.1 - 0.012 14.8 0.0 0.026 13.7 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AIG1 PF04548.11 KEY73482.1 - 0.034 13.2 0.2 0.074 12.1 0.0 1.6 2 0 0 2 2 2 0 AIG1 family KaiC PF06745.8 KEY73482.1 - 0.034 13.2 0.0 0.096 11.7 0.0 1.8 1 0 0 1 1 1 0 KaiC MMR_HSR1 PF01926.18 KEY73482.1 - 0.056 13.3 0.1 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase T2SE PF00437.15 KEY73482.1 - 0.076 11.9 1.2 0.23 10.3 0.8 1.8 1 1 0 1 1 1 0 Type II/IV secretion system protein Ank_2 PF12796.2 KEY73484.1 - 0.00019 21.6 3.5 0.17 12.2 0.1 3.6 1 1 0 3 3 3 3 Ankyrin repeats (3 copies) CVNH PF08881.5 KEY73487.1 - 3.2e-30 104.4 0.1 3.5e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 CVNH domain CD4-extracel PF09191.5 KEY73487.1 - 0.12 12.3 0.2 0.27 11.2 0.1 1.6 1 1 1 2 2 2 0 CD4, extracellular FAD_binding_3 PF01494.14 KEY73489.1 - 1.2e-63 215.3 0.0 6.3e-63 212.9 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KEY73489.1 - 0.0003 20.7 0.1 0.00093 19.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Phe_hydrox_dim PF07976.7 KEY73489.1 - 0.00031 20.4 0.0 0.00074 19.1 0.0 1.7 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_3 PF13738.1 KEY73489.1 - 0.009 16.0 0.0 0.019 15.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEY73489.1 - 0.035 12.9 0.3 0.07 12.0 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 KEY73489.1 - 0.039 13.0 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KEY73489.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY73489.1 - 0.14 11.0 1.1 0.27 10.1 0.3 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein K_oxygenase PF13434.1 KEY73489.1 - 0.18 10.6 0.1 2.1 7.1 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) MFS_1 PF07690.11 KEY73490.1 - 1.7e-23 82.9 73.8 4.4e-19 68.4 27.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GMC_oxred_N PF00732.14 KEY73491.1 - 9.5e-48 162.8 0.0 1.3e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY73491.1 - 5.3e-38 130.5 0.0 8.3e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KEY73491.1 - 1.8e-06 27.1 2.4 0.014 14.3 0.7 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEY73491.1 - 0.0036 16.2 0.2 0.014 14.3 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEY73491.1 - 0.026 14.4 0.0 0.086 12.7 0.0 1.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY73491.1 - 0.042 13.9 0.1 7.7 6.5 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY73491.1 - 0.047 13.7 0.6 0.047 13.7 0.4 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HHH PF00633.18 KEY73491.1 - 0.064 12.9 0.1 2.6 7.9 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif Tyrosinase PF00264.15 KEY73492.1 - 1.2e-33 117.1 1.2 2.1e-33 116.3 0.9 1.4 1 1 0 1 1 1 1 Common central domain of tyrosinase DUF1814 PF08843.6 KEY73493.1 - 0.066 12.9 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF1814) Glyco_hydro_43 PF04616.9 KEY73494.1 - 1.7e-53 181.6 2.2 2.2e-53 181.2 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sugar_tr PF00083.19 KEY73495.1 - 4.1e-97 325.5 20.2 4.7e-97 325.4 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY73495.1 - 1.8e-34 118.9 26.5 1.1e-25 90.0 2.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 KEY73495.1 - 1.2e-06 26.9 4.8 0.003 15.7 0.0 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector MFS_2 PF13347.1 KEY73495.1 - 4.8e-06 25.2 23.9 3.8e-05 22.2 0.6 3.1 3 1 0 3 3 3 2 MFS/sugar transport protein PUCC PF03209.10 KEY73495.1 - 0.003 16.3 1.8 0.003 16.3 1.3 2.2 2 0 0 2 2 2 1 PUCC protein HATPase_c PF02518.21 KEY73497.1 - 2.3e-24 85.2 0.0 6e-24 83.9 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KEY73497.1 - 5.1e-24 84.4 0.1 1.3e-23 83.1 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KEY73497.1 - 5e-17 61.6 0.1 2.3e-16 59.5 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 KEY73497.1 - 2.2e-13 50.4 0.0 8.4e-12 45.3 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 KEY73497.1 - 5.8e-09 35.9 0.0 7.3e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 KEY73497.1 - 5.6e-08 32.5 0.0 1.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold NAD_binding_10 PF13460.1 KEY73498.1 - 1.6e-18 67.3 0.0 1.7e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KEY73498.1 - 3e-09 36.5 0.0 5.9e-09 35.5 0.0 1.4 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 KEY73498.1 - 0.00037 19.9 0.0 0.00096 18.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Zn_clus PF00172.13 KEY73499.1 - 6.4e-09 35.5 11.0 1.1e-08 34.8 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.3 KEY73499.1 - 0.079 12.6 0.2 0.23 11.1 0.2 1.8 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Metallophos PF00149.23 KEY73500.1 - 0.00095 18.6 5.2 0.0018 17.6 3.6 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEY73500.1 - 0.011 15.5 0.1 0.022 14.5 0.0 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain MFS_1 PF07690.11 KEY73501.1 - 7.1e-33 113.7 31.4 7.1e-32 110.4 22.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Trypsin PF00089.21 KEY73502.1 - 1.1e-07 31.6 11.7 5.8e-07 29.3 8.1 1.9 1 1 0 1 1 1 1 Trypsin Pro_Al_protease PF02983.9 KEY73502.1 - 8.3e-05 22.4 0.2 8.3e-05 22.4 0.2 2.8 3 1 0 3 3 3 1 Alpha-lytic protease prodomain Tannase PF07519.6 KEY73503.1 - 1.3e-94 317.5 0.0 2.1e-93 313.5 0.0 1.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 KEY73503.1 - 0.00031 20.7 0.0 0.0013 18.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY73503.1 - 0.0062 16.3 0.1 3.9 7.2 0.0 2.6 2 1 1 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY73503.1 - 0.26 10.8 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Amidase PF01425.16 KEY73504.1 - 2.6e-76 257.2 0.2 9.2e-73 245.5 0.0 2.4 2 1 1 3 3 3 2 Amidase Ferric_reduct PF01794.14 KEY73505.1 - 1.9e-16 60.3 19.4 5.4e-16 58.8 13.4 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KEY73505.1 - 9.4e-09 35.3 0.0 0.0035 17.2 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KEY73505.1 - 1.4e-05 24.8 0.0 0.00055 19.7 0.0 2.4 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 KEY73505.1 - 3.6e-05 24.2 0.0 6.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain zf-MYND PF01753.13 KEY73506.1 - 1.5e-10 40.7 13.5 2.7e-10 39.9 9.3 1.4 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 KEY73506.1 - 2.7 7.7 11.5 42 3.9 8.0 2.3 1 1 0 1 1 1 0 HIT zinc finger GMC_oxred_C PF05199.8 KEY73507.1 - 4.2e-27 95.2 0.2 1.1e-26 93.7 0.1 1.8 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KEY73507.1 - 6e-27 94.5 5.8 9.5e-22 77.4 0.3 3.1 1 1 2 3 3 3 2 GMC oxidoreductase DAO PF01266.19 KEY73507.1 - 2.5e-05 23.3 1.5 0.0055 15.6 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEY73507.1 - 8.1e-05 21.6 0.4 0.00016 20.6 0.3 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEY73507.1 - 0.0005 19.9 0.1 0.0011 18.8 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEY73507.1 - 0.0014 17.5 5.6 0.027 13.3 0.7 2.3 1 1 1 2 2 2 2 FAD binding domain HI0933_like PF03486.9 KEY73507.1 - 0.016 13.6 0.7 0.028 12.8 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein SLAC1 PF03595.12 KEY73508.1 - 9e-65 218.4 43.4 1e-64 218.3 30.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Glyco_hydro_61 PF03443.9 KEY73509.1 - 7.6e-59 199.1 0.2 8.5e-59 198.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 KEY73509.1 - 0.029 14.4 0.0 0.3 11.1 0.0 2.4 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Pectate_lyase PF03211.8 KEY73510.1 - 1.2e-63 214.4 0.0 1.5e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Pectate lyase Collagen PF01391.13 KEY73511.1 - 1.8e-15 56.1 84.7 1.3e-08 34.2 20.3 4.5 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) p450 PF00067.17 KEY73512.1 - 7.5e-40 136.8 0.0 2.3e-39 135.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 KEY73513.1 - 1.4e-14 54.5 0.0 2.3e-14 53.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY73513.1 - 1.3e-08 34.7 0.0 1.5e-06 27.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY73513.1 - 0.00046 19.9 0.0 0.00075 19.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KEY73513.1 - 0.0033 17.0 0.0 0.0044 16.6 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase DUF3089 PF11288.3 KEY73513.1 - 0.015 14.4 0.1 0.13 11.4 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3089) LCAT PF02450.10 KEY73513.1 - 0.15 11.0 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase GHMP_kinases_C PF08544.8 KEY73514.1 - 0.11 12.6 1.6 5.2 7.3 0.0 2.2 2 0 0 2 2 2 0 GHMP kinases C terminal Peptidase_C14 PF00656.17 KEY73515.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Caspase domain Ank PF00023.25 KEY73516.1 - 4.2e-36 120.9 6.1 6.4e-07 28.8 0.0 9.0 8 1 0 8 8 8 6 Ankyrin repeat Ank_2 PF12796.2 KEY73516.1 - 1.2e-33 115.2 0.1 8.6e-16 58.0 0.2 6.5 4 2 3 7 7 7 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEY73516.1 - 2.3e-29 101.1 0.7 0.00074 19.9 0.0 7.8 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY73516.1 - 1.3e-25 86.8 0.7 0.00023 21.1 0.0 9.4 9 0 0 9 9 9 4 Ankyrin repeat Pkinase PF00069.20 KEY73516.1 - 3e-24 85.5 0.0 4.7e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.1 KEY73516.1 - 1.6e-22 78.9 2.2 7.1e-06 26.0 0.1 7.4 7 0 0 7 7 7 4 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.12 KEY73516.1 - 1.8e-16 60.0 0.0 3e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KEY73516.1 - 0.03 13.1 0.0 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cerato-platanin PF07249.7 KEY73517.1 - 0.00026 20.9 0.7 0.00061 19.7 0.1 1.9 2 0 0 2 2 2 1 Cerato-platanin Bac_rhamnosid PF05592.6 KEY73518.1 - 2.8e-176 586.7 0.0 3.4e-176 586.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 KEY73518.1 - 1.4e-44 151.6 0.0 3e-44 150.5 0.0 1.6 2 0 0 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain Sugar_tr PF00083.19 KEY73519.1 - 5.2e-87 292.2 33.2 5.9e-87 292.1 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY73519.1 - 6.8e-27 94.0 40.2 1e-26 93.4 24.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MacB_PCD PF12704.2 KEY73519.1 - 0.063 12.8 1.0 0.16 11.5 0.7 1.7 1 0 0 1 1 1 0 MacB-like periplasmic core domain Bac_rhamnosid PF05592.6 KEY73520.1 - 2.4e-22 78.8 0.1 4.2e-20 71.4 0.0 2.3 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase GDE_C PF06202.9 KEY73520.1 - 0.00043 19.1 0.3 0.005 15.6 0.2 2.1 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.13 KEY73520.1 - 0.0045 15.6 0.3 0.0068 15.1 0.2 1.1 1 0 0 1 1 1 1 Trehalase DUF998 PF06197.8 KEY73521.1 - 0.0011 18.3 8.4 0.0011 18.3 5.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF998) Na_H_Exchanger PF00999.16 KEY73523.1 - 1.1e-68 231.5 48.3 1.6e-68 231.0 33.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family HhH-GPD PF00730.20 KEY73524.1 - 1.7e-19 70.1 0.0 3.4e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 KEY73524.1 - 3.4e-16 58.6 0.0 6.9e-16 57.6 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.18 KEY73524.1 - 3.2e-05 23.3 0.1 8.4e-05 22.0 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 KEY73524.1 - 0.0052 16.9 0.1 0.38 10.9 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain DnaA_N PF11638.3 KEY73524.1 - 0.038 13.5 0.1 0.073 12.6 0.1 1.4 1 0 0 1 1 1 0 DnaA N-terminal domain Cofilin_ADF PF00241.15 KEY73525.1 - 3.8e-13 49.4 0.0 4.2e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein AA_permease_2 PF13520.1 KEY73526.1 - 2.4e-43 148.2 52.8 3.1e-43 147.9 36.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEY73526.1 - 1.8e-25 89.2 48.2 2.3e-25 88.8 33.4 1.1 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.3 KEY73526.1 - 0.073 12.7 0.5 0.14 11.8 0.4 1.4 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Telethonin PF09470.5 KEY73527.1 - 0.18 11.2 0.5 8.3 5.8 0.1 2.1 2 0 0 2 2 2 0 Telethonin protein CBM_21 PF03370.8 KEY73529.1 - 7.5e-35 119.3 0.1 1.3e-34 118.5 0.1 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 KEY73529.1 - 0.42 10.7 2.1 0.95 9.5 1.5 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) Shikimate_dh_N PF08501.6 KEY73530.1 - 1.1e-20 73.4 0.0 2.1e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KEY73530.1 - 4.4e-13 49.4 0.0 6.5e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.10 KEY73530.1 - 0.032 12.9 0.0 0.049 12.3 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family YoaP PF14268.1 KEY73530.1 - 0.13 11.4 0.0 0.39 9.9 0.0 1.7 1 0 0 1 1 1 0 YoaP-like CPSase_L_chain PF00289.17 KEY73530.1 - 0.15 12.1 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain AP_endonuc_2 PF01261.19 KEY73531.1 - 1.9e-30 105.7 0.7 3e-30 105.1 0.1 1.5 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel DHquinase_II PF01220.14 KEY73532.1 - 2e-59 198.9 0.1 2.2e-59 198.7 0.1 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Sugar_tr PF00083.19 KEY73533.1 - 3.1e-126 421.5 22.3 3.6e-126 421.3 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY73533.1 - 5.3e-23 81.2 29.2 5.3e-23 81.2 20.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.13 KEY73534.1 - 5.7e-07 29.3 12.3 1.1e-06 28.4 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY73534.1 - 0.0001 21.2 1.7 0.0014 17.5 1.2 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain DHquinase_I PF01487.10 KEY73536.1 - 3.4e-27 95.5 0.0 5.4e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 KEY73536.1 - 9.3e-18 64.0 0.0 2.1e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 KEY73536.1 - 2.5e-17 63.1 0.0 4.4e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 KEY73536.1 - 6.6e-11 42.4 0.2 1.7e-10 41.1 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Ins134_P3_kin PF05770.6 KEY73536.1 - 0.002 17.2 0.0 0.0034 16.4 0.0 1.2 1 0 0 1 1 1 1 Inositol 1, 3, 4-trisphosphate 5/6-kinase AAA_33 PF13671.1 KEY73536.1 - 0.0026 17.6 0.2 0.0096 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KEY73536.1 - 0.018 15.3 0.0 0.035 14.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ThiF PF00899.16 KEY73536.1 - 0.039 13.7 0.6 0.087 12.6 0.0 1.8 2 0 0 2 2 2 0 ThiF family OCD_Mu_crystall PF02423.10 KEY73536.1 - 0.041 12.6 0.1 0.072 11.8 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family NACHT PF05729.7 KEY73536.1 - 0.052 13.1 0.0 0.99 9.0 0.0 2.3 2 0 0 2 2 2 0 NACHT domain F420_oxidored PF03807.12 KEY73536.1 - 0.14 12.5 0.0 0.97 9.9 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AAA_17 PF13207.1 KEY73536.1 - 0.15 12.8 0.0 0.46 11.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain FAD_binding_4 PF01565.18 KEY73538.1 - 1.5e-22 79.5 0.6 2.8e-22 78.6 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY73538.1 - 0.013 15.3 1.8 0.031 14.1 0.0 2.5 3 0 0 3 3 3 0 Berberine and berberine like Ank_2 PF12796.2 KEY73540.1 - 9.4e-12 45.1 0.0 8e-09 35.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEY73540.1 - 4.5e-11 42.6 0.0 1.3e-06 28.4 0.0 3.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 KEY73540.1 - 8.4e-10 37.9 0.3 0.0042 16.8 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KEY73540.1 - 4e-07 30.3 0.0 0.013 15.9 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY73540.1 - 6.5e-06 25.8 0.1 0.92 9.9 0.0 4.1 3 1 0 3 3 3 2 Ankyrin repeat Pox_A22 PF04848.8 KEY73540.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A22 protein GDPD PF03009.12 KEY73541.1 - 0.00069 19.1 0.0 0.0081 15.6 0.0 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family DUF1768 PF08719.6 KEY73543.1 - 3.8e-46 156.6 0.1 4.7e-46 156.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Peptidase_M49 PF03571.10 KEY73545.1 - 8.3e-176 585.2 0.0 1e-175 584.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 2C_adapt PF08793.5 KEY73545.1 - 0.023 14.5 0.4 0.12 12.3 0.1 2.4 3 0 0 3 3 3 0 2-cysteine adaptor domain Peptidase_M24 PF00557.19 KEY73546.1 - 7.6e-54 182.4 0.1 1.6e-53 181.3 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KEY73546.1 - 4.3e-26 90.8 0.0 8.7e-26 89.9 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain MutL PF13941.1 KEY73547.1 - 1.3e-05 23.7 0.0 0.0011 17.4 0.0 2.3 1 1 1 2 2 2 2 MutL protein BcrAD_BadFG PF01869.15 KEY73547.1 - 0.0049 16.2 0.2 0.098 11.9 0.0 2.4 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Actin PF00022.14 KEY73547.1 - 0.091 11.1 0.0 0.48 8.7 0.0 1.9 2 0 0 2 2 2 0 Actin FtsA PF14450.1 KEY73547.1 - 0.18 11.6 0.3 8.6 6.2 0.1 2.4 2 1 0 2 2 2 0 Cell division protein FtsA HeLo PF14479.1 KEY73549.1 - 7.6e-05 22.5 4.1 0.098 12.3 0.0 3.3 3 1 1 4 4 4 2 Prion-inhibition and propagation DUF814 PF05670.8 KEY73550.1 - 3.2e-16 58.9 0.4 3.3e-15 55.7 0.2 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF814) NACHT PF05729.7 KEY73551.1 - 7.6e-09 35.4 0.1 2.8e-08 33.6 0.1 2.0 1 1 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 KEY73551.1 - 0.00022 22.0 0.0 0.00075 20.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEY73551.1 - 0.0023 17.7 2.2 0.64 9.8 0.0 3.0 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 KEY73551.1 - 0.0028 17.7 1.9 0.028 14.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KEY73551.1 - 0.0055 16.1 0.3 0.031 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 KEY73551.1 - 0.009 16.3 0.1 0.034 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KEY73551.1 - 0.077 13.3 1.7 0.31 11.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 KEY73551.1 - 0.093 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 KEY73551.1 - 0.12 12.5 0.1 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 KEY73551.1 - 0.13 12.5 1.2 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Velvet PF11754.3 KEY73552.1 - 0.00039 20.0 0.1 0.0081 15.7 0.0 2.0 1 1 1 2 2 2 2 Velvet factor BolA PF01722.13 KEY73554.1 - 5.7e-15 55.0 0.0 7.5e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein DUF4593 PF15263.1 KEY73554.1 - 0.0012 18.7 0.5 0.0016 18.3 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4593) ACC_central PF08326.7 KEY73555.1 - 5.3e-249 828.0 0.0 6.6e-249 827.7 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 KEY73555.1 - 3.7e-175 582.9 0.0 5.7e-175 582.3 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KEY73555.1 - 1.2e-52 178.2 0.0 2.2e-52 177.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KEY73555.1 - 7.6e-24 83.9 0.0 1.5e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KEY73555.1 - 7.1e-22 77.4 0.0 3.5e-19 68.7 0.0 3.0 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 KEY73555.1 - 1.1e-16 60.2 0.1 2.9e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KEY73555.1 - 2.3e-10 40.5 0.0 5.6e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KEY73555.1 - 4.1e-08 32.3 0.0 1.6e-05 23.8 0.0 3.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KEY73555.1 - 0.0013 18.2 0.0 0.0028 17.0 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KEY73555.1 - 0.011 15.5 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp PF02222.17 KEY73555.1 - 0.058 12.7 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain DUF947 PF06102.7 KEY73555.1 - 5.6 6.7 4.5 1.3 8.8 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF947) NUDE_C PF04880.8 KEY73556.1 - 4.7e-21 75.8 3.8 4.7e-21 75.8 2.6 5.0 2 1 3 5 5 2 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 KEY73556.1 - 0.0026 18.0 7.6 0.0026 18.0 5.3 3.5 1 1 2 3 3 3 1 Protein of unknown function (DUF904) ERM PF00769.14 KEY73556.1 - 0.01 15.3 22.7 0.02 14.4 15.7 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Tropomyosin_1 PF12718.2 KEY73556.1 - 0.01 15.6 31.8 2.7 7.8 3.7 3.8 2 1 1 3 3 3 0 Tropomyosin like WEMBL PF05701.6 KEY73556.1 - 0.018 13.5 26.7 0.027 12.9 18.5 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Chibby PF14645.1 KEY73556.1 - 0.15 11.9 14.1 0.69 9.8 1.3 2.5 1 1 1 2 2 2 0 Chibby family EF1G PF00647.14 KEY73556.1 - 0.17 11.6 0.3 0.36 10.5 0.2 1.5 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain AAA_13 PF13166.1 KEY73556.1 - 0.81 8.0 17.1 1.2 7.5 11.9 1.1 1 0 0 1 1 1 0 AAA domain Peptidase_S46 PF10459.4 KEY73556.1 - 1.5 7.1 12.0 1.9 6.7 8.3 1.1 1 0 0 1 1 1 0 Peptidase S46 IncA PF04156.9 KEY73556.1 - 2.5 7.6 34.8 0.93 9.0 15.0 2.5 2 1 1 3 3 3 0 IncA protein Tropomyosin PF00261.15 KEY73556.1 - 3.8 6.5 34.2 3.6 6.6 22.0 2.0 2 0 0 2 2 2 0 Tropomyosin CENP-F_leu_zip PF10473.4 KEY73556.1 - 6.3 6.6 36.3 1.7 8.4 7.7 2.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 KEY73556.1 - 9.2 6.6 22.8 0.19 12.0 4.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF972) RINGv PF12906.2 KEY73557.1 - 1e-16 60.6 8.8 1.8e-16 59.8 6.1 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KEY73557.1 - 0.14 12.0 7.7 0.27 11.1 5.3 1.5 1 0 0 1 1 1 0 Ring finger domain zf-Apc11 PF12861.2 KEY73557.1 - 0.15 11.9 4.8 0.28 11.0 2.2 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_PEP_C PF04513.7 KEY73559.1 - 0.0042 16.9 0.2 0.0042 16.9 0.1 2.5 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4085 PF13315.1 KEY73559.1 - 0.36 10.1 5.9 7.7 5.8 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4085) Gln-synt_C PF00120.19 KEY73560.1 - 5.5e-56 189.5 0.0 7.6e-56 189.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain GMC_oxred_N PF00732.14 KEY73561.1 - 2.4e-60 204.2 0.0 3.2e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY73561.1 - 4.8e-36 124.1 0.0 1.2e-35 122.9 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KEY73561.1 - 9.7e-06 24.7 0.0 5.8e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY73561.1 - 9.1e-05 22.4 0.0 0.00024 21.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEY73561.1 - 0.00063 18.7 0.0 0.0071 15.2 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KEY73561.1 - 0.0035 16.3 0.0 0.0051 15.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEY73561.1 - 0.016 15.1 0.0 0.043 13.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEY73561.1 - 0.049 12.0 0.0 0.075 11.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein ADH_N PF08240.7 KEY73562.1 - 4.3e-21 74.7 3.1 4.3e-21 74.7 2.2 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY73562.1 - 6.5e-12 45.1 0.0 1.9e-11 43.5 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KEY73562.1 - 0.0002 20.5 0.1 0.00034 19.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KEY73562.1 - 0.0081 15.7 0.1 0.014 14.9 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 KEY73562.1 - 0.066 12.7 0.2 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 3HCDH_N PF02737.13 KEY73562.1 - 0.12 12.0 0.2 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 KEY73562.1 - 0.24 11.2 2.5 0.47 10.2 1.7 1.5 1 0 0 1 1 1 0 ThiF family Fungal_trans_2 PF11951.3 KEY73563.1 - 0.0015 17.1 0.1 0.0028 16.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KEY73564.1 - 1.2e-14 53.8 25.8 7.8e-11 41.2 10.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Chromo PF00385.19 KEY73565.1 - 8.1e-08 31.8 6.0 9.6e-06 25.1 0.2 2.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Nexin_C PF08628.7 KEY73565.1 - 0.17 11.9 2.9 2.4 8.2 0.2 2.6 2 0 0 2 2 2 0 Sorting nexin C terminal HTH_Tnp_Tc5 PF03221.11 KEY73566.1 - 7.2e-10 38.5 0.0 1.8e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 KEY73566.1 - 2.3e-05 23.6 0.1 0.004 16.3 0.0 2.4 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_psq PF05225.11 KEY73566.1 - 0.018 14.6 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain MFS_1 PF07690.11 KEY73567.1 - 2.2e-07 29.9 1.8 2.7e-07 29.6 1.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY73567.1 - 0.00016 20.3 1.3 0.00022 19.9 0.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Cyclin_N PF00134.18 KEY73570.1 - 4e-34 116.9 0.1 1.2e-33 115.3 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KEY73570.1 - 5.5e-31 106.9 0.2 9.5e-31 106.1 0.2 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Dimer_Tnp_hAT PF05699.9 KEY73571.1 - 1.8e-11 43.4 0.2 1.8e-11 43.4 0.2 1.8 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 KEY73571.1 - 0.0051 16.7 0.2 0.0086 16.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) zf-BED PF02892.10 KEY73572.1 - 0.15 11.8 5.1 0.58 9.9 3.5 2.1 1 1 0 1 1 1 0 BED zinc finger Glyco_hydro_12 PF01670.11 KEY73573.1 - 3.7e-39 134.0 0.2 6.8e-39 133.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Ank_4 PF13637.1 KEY73573.1 - 1.5e-11 44.4 0.1 1.8e-06 28.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEY73573.1 - 1.4e-10 41.3 0.0 2.9e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KEY73573.1 - 1.5e-09 37.1 0.0 9.8e-08 31.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 KEY73573.1 - 6.4e-06 25.9 0.0 6.3e-05 22.8 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 KEY73573.1 - 7.8e-06 25.9 0.1 0.00021 21.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DYW_deaminase PF14432.1 KEY73573.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases ADH_zinc_N_2 PF13602.1 KEY73574.1 - 0.00018 22.3 0.0 0.00021 22.1 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Kelch_4 PF13418.1 KEY73574.1 - 0.017 14.8 0.1 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Galactose oxidase, central domain Kelch_3 PF13415.1 KEY73574.1 - 0.099 12.8 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Galactose oxidase, central domain Glyco_hydro_32N PF00251.15 KEY73576.1 - 3.4e-73 246.6 0.2 4.1e-73 246.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KEY73576.1 - 4e-12 46.3 0.0 7.4e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_62 PF03664.8 KEY73576.1 - 0.0013 17.9 0.4 0.0025 16.9 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 BNR PF02012.15 KEY73576.1 - 0.009 15.6 0.6 0.28 11.1 0.0 3.6 2 0 0 2 2 2 1 BNR/Asp-box repeat Glyco_hydro_32N PF00251.15 KEY73577.1 - 4e-69 233.3 2.1 5.3e-69 232.9 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KEY73577.1 - 3.7e-09 36.8 0.1 8.3e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.15 KEY73578.1 - 2.1e-61 207.9 0.1 3.1e-61 207.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KEY73578.1 - 0.0001 22.5 0.0 0.00027 21.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal PaRep2a PF07903.6 KEY73578.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 PaRep2a protein Sugar_tr PF00083.19 KEY73579.1 - 4.9e-114 381.3 26.8 4.7e-67 226.5 1.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KEY73579.1 - 2.7e-23 82.2 27.7 7.7e-15 54.4 7.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily EBP PF05241.7 KEY73579.1 - 0.033 13.2 6.0 0.071 12.1 4.1 1.5 1 0 0 1 1 1 0 Emopamil binding protein CHASE3 PF05227.8 KEY73579.1 - 0.094 12.3 0.1 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 CHASE3 domain LRR19-TM PF15176.1 KEY73579.1 - 0.24 11.1 1.1 22 4.7 0.0 3.3 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain DUF3154 PF11351.3 KEY73579.1 - 0.52 10.0 7.2 2.3 7.9 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3154) Peptidase_S7 PF00949.16 KEY73580.1 - 0.016 14.6 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Transferase PF02458.10 KEY73581.1 - 5.2e-06 25.1 0.0 0.00041 18.9 0.0 2.5 2 1 0 2 2 2 2 Transferase family NACHT PF05729.7 KEY73582.1 - 3e-11 43.2 0.0 7.6e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEY73582.1 - 2.6e-05 24.2 0.1 0.00021 21.3 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEY73582.1 - 0.0033 17.5 0.0 0.014 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KEY73582.1 - 0.0056 15.5 0.0 0.013 14.3 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain KaiC PF06745.8 KEY73582.1 - 0.032 13.3 0.0 0.072 12.1 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA PF00004.24 KEY73582.1 - 0.045 13.9 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KEY73582.1 - 0.046 13.1 0.0 0.87 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KEY73582.1 - 0.051 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain DUF2075 PF09848.4 KEY73582.1 - 0.055 12.4 0.0 0.12 11.3 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 KEY73582.1 - 0.086 13.6 0.0 0.29 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KEY73582.1 - 0.094 12.5 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain SurE PF01975.12 KEY73583.1 - 8.7e-29 100.2 0.0 1.3e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE PP-binding PF00550.20 KEY73584.1 - 1.7e-10 41.0 0.0 3.3e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.1 KEY73585.1 - 7.5e-29 100.8 0.0 1.2e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.21 KEY73585.1 - 2.2e-17 62.7 0.0 5.5e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KEY73585.1 - 6.1e-17 61.9 0.0 1.8e-16 60.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY73585.1 - 1.6e-12 47.4 0.0 3.6e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY73585.1 - 5.2e-11 42.8 0.0 1.5e-10 41.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY73585.1 - 1.1e-10 42.0 0.0 3.4e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY73585.1 - 2e-10 40.4 0.0 3.7e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY73585.1 - 1.4e-06 27.6 0.0 2.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEY73585.1 - 6.8e-06 26.3 0.0 2.5e-05 24.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY73585.1 - 0.00027 20.9 0.0 0.0031 17.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Rio2_N PF09202.6 KEY73585.1 - 0.082 12.9 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 Rio2, N-terminal Methyltransf_16 PF10294.4 KEY73585.1 - 0.12 11.7 0.0 0.36 10.2 0.0 1.7 1 1 0 1 1 1 0 Putative methyltransferase HET PF06985.6 KEY73586.1 - 5.8e-38 130.1 0.0 9.1e-38 129.5 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.8 KEY73586.1 - 0.026 13.4 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) p450 PF00067.17 KEY73587.1 - 5.8e-40 137.1 0.0 6.8e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SNF2_N PF00176.18 KEY73589.1 - 1.7e-66 224.0 0.1 2.6e-66 223.4 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEY73589.1 - 6.6e-11 41.9 0.1 3.9e-10 39.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEY73589.1 - 4.3e-08 32.8 0.0 2.5e-07 30.3 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 KEY73589.1 - 0.00029 20.4 5.4 0.00073 19.2 3.7 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KEY73589.1 - 0.0011 18.6 5.0 0.0026 17.3 3.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEY73589.1 - 0.0015 18.5 1.1 0.0058 16.6 0.8 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD_2 PF06733.10 KEY73589.1 - 0.011 15.1 0.0 0.028 13.8 0.0 1.7 1 0 0 1 1 1 0 DEAD_2 zf-C3HC4_4 PF15227.1 KEY73589.1 - 0.16 11.8 2.3 0.4 10.5 1.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KEY73589.1 - 0.39 10.4 5.6 1.1 8.9 3.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEY73589.1 - 0.69 9.7 11.8 0.035 13.9 3.6 2.4 2 0 0 2 2 2 0 Ring finger domain DUF2029 PF09594.5 KEY73590.1 - 9.7e-05 21.9 0.1 0.00015 21.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2029) SKG6 PF08693.5 KEY73590.1 - 0.00056 19.1 0.1 0.0014 17.9 0.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CCER1 PF15482.1 KEY73590.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 Podoplanin PF05808.6 KEY73590.1 - 0.036 13.6 0.1 0.057 12.9 0.1 1.3 1 0 0 1 1 1 0 Podoplanin DUF4448 PF14610.1 KEY73590.1 - 0.066 12.7 0.0 0.092 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) NACHT PF05729.7 KEY73591.1 - 2.6e-09 36.9 0.0 6.8e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEY73591.1 - 1.5e-06 28.3 0.1 8.2e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 KEY73591.1 - 3.6e-06 26.0 0.0 1.9e-05 23.6 0.0 2.3 2 1 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.1 KEY73591.1 - 1.1e-05 25.5 0.2 8.9e-05 22.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KEY73591.1 - 5.7e-05 23.2 0.1 0.00031 20.8 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA PF00004.24 KEY73591.1 - 8.5e-05 22.7 0.1 0.00059 20.0 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KEY73591.1 - 0.00014 22.1 1.4 0.0017 18.6 0.0 3.0 3 0 0 3 3 3 1 ABC transporter AAA_19 PF13245.1 KEY73591.1 - 0.0012 18.5 0.0 0.0036 17.0 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activat PF00158.21 KEY73591.1 - 0.002 17.6 0.0 0.0054 16.2 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain DUF2075 PF09848.4 KEY73591.1 - 0.0022 17.0 0.6 0.0062 15.5 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 KEY73591.1 - 0.0026 17.6 0.0 0.032 14.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEY73591.1 - 0.0036 16.7 6.5 0.0051 16.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain Torsin PF06309.6 KEY73591.1 - 0.0084 15.9 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 Torsin AAA_17 PF13207.1 KEY73591.1 - 0.0084 16.9 0.1 0.0084 16.9 0.1 4.0 4 2 0 4 4 4 1 AAA domain DUF87 PF01935.12 KEY73591.1 - 0.0087 15.8 2.6 0.024 14.4 0.0 2.8 3 0 0 3 3 2 1 Domain of unknown function DUF87 AAA_18 PF13238.1 KEY73591.1 - 0.019 15.2 3.1 0.04 14.2 0.1 3.1 2 1 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 KEY73591.1 - 0.02 14.5 4.2 0.044 13.4 0.0 3.2 3 1 0 3 3 3 0 NTPase AAA_33 PF13671.1 KEY73591.1 - 0.03 14.1 1.5 0.078 12.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 KEY73591.1 - 0.07 12.7 0.1 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase CbiA PF01656.18 KEY73591.1 - 0.15 11.4 0.7 22 4.3 0.0 2.8 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Glyco_transf_54 PF04666.8 KEY73592.1 - 5e-15 55.0 0.0 4.2e-14 51.9 0.0 2.0 1 1 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region T5orf172 PF10544.4 KEY73593.1 - 1.5e-13 51.0 0.7 3.8e-13 49.6 0.1 2.1 2 1 0 2 2 2 1 T5orf172 domain MUG113 PF13455.1 KEY73593.1 - 3.4e-10 40.2 0.2 1.1e-09 38.6 0.1 1.9 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 GST_N_3 PF13417.1 KEY73594.1 - 1.5e-12 47.5 0.0 2.5e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEY73594.1 - 8.6e-09 35.2 0.0 1.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KEY73594.1 - 0.00085 19.4 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KEY73594.1 - 0.018 14.9 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain VCBS PF13517.1 KEY73595.1 - 6.6e-22 77.6 51.2 1.1e-09 38.5 1.6 7.4 2 2 5 7 7 7 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KEY73595.1 - 6.9e-15 54.2 33.5 0.00025 20.6 0.8 6.5 6 0 0 6 6 6 5 FG-GAP repeat TcdB_toxin_midN PF12256.3 KEY73595.1 - 7.4e-13 48.3 8.4 0.016 14.6 0.0 5.3 4 1 1 5 5 5 5 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_2 PF13472.1 KEY73595.1 - 2.4e-11 44.0 0.5 6.2e-11 42.7 0.0 2.0 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family EF-hand_5 PF13202.1 KEY73595.1 - 0.62 9.4 12.0 4.7 6.7 0.3 4.7 4 0 0 4 4 4 0 EF hand EF-hand_1 PF00036.27 KEY73595.1 - 1.4 8.3 10.8 1.5 8.2 0.2 4.9 5 0 0 5 5 5 0 EF hand HET PF06985.6 KEY73596.1 - 5.1e-22 78.5 0.0 2.2e-21 76.5 0.0 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 KEY73597.1 - 3.4e-22 79.1 0.1 1.6e-21 76.8 0.0 2.3 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 KEY73598.1 - 6.3e-25 88.0 0.1 8.2e-25 87.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY73598.1 - 3e-11 43.5 0.0 3.7e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY73598.1 - 8.4e-09 35.3 0.1 1.3e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY73598.1 - 0.0023 17.3 0.0 0.005 16.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 KEY73598.1 - 0.0024 17.3 0.3 0.0049 16.4 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KEY73598.1 - 0.024 14.6 0.2 0.051 13.5 0.1 1.7 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KEY73598.1 - 0.045 13.5 0.4 0.096 12.4 0.3 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 KEY73598.1 - 0.11 11.4 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AAA_30 PF13604.1 KEY73598.1 - 0.11 12.0 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 KEY73599.1 - 1.1e-29 103.2 49.2 3.3e-28 98.4 32.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF912 PF06024.7 KEY73599.1 - 0.057 13.4 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3169 PF11368.3 KEY73599.1 - 0.058 12.6 0.0 0.058 12.6 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3169) DUF1469 PF07332.6 KEY73599.1 - 0.058 13.1 0.3 0.058 13.1 0.2 4.8 4 1 2 6 6 6 0 Protein of unknown function (DUF1469) p450 PF00067.17 KEY73600.1 - 3.1e-47 161.1 0.0 5.5e-47 160.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_16 PF00722.16 KEY73601.1 - 1.6e-19 69.9 0.1 2.2e-19 69.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 KEY73601.1 - 1.4e-06 26.7 4.3 0.0049 15.0 0.1 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Methyltransf_2 PF00891.13 KEY73602.1 - 2.4e-29 102.2 0.0 3.3e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Sigma70_r4 PF04545.11 KEY73602.1 - 0.0082 15.4 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 ABC_tran PF00005.22 KEY73603.1 - 8.9e-35 119.9 0.0 2.5e-34 118.5 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 KEY73603.1 - 4.7e-20 72.1 8.5 4.7e-20 72.1 5.9 1.9 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 KEY73603.1 - 3.3e-06 26.5 0.5 0.00062 19.0 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEY73603.1 - 4.5e-05 23.5 0.1 0.12 12.3 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.1 KEY73603.1 - 0.00044 20.3 0.4 0.0044 17.1 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KEY73603.1 - 0.001 18.5 0.1 0.0024 17.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KEY73603.1 - 0.014 15.3 1.0 0.044 13.7 0.6 1.8 1 1 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KEY73603.1 - 0.017 14.6 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 KEY73603.1 - 0.028 13.8 0.9 0.12 11.8 0.3 2.3 2 1 0 2 2 2 0 AAA-like domain SbcCD_C PF13558.1 KEY73603.1 - 0.071 13.0 0.5 0.48 10.3 0.3 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 KEY73603.1 - 0.081 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KEY73603.1 - 0.17 11.0 0.0 0.42 9.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Pex24p PF06398.6 KEY73603.1 - 0.19 10.4 1.3 0.5 9.0 0.5 1.9 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF3357 PF11837.3 KEY73603.1 - 0.3 10.9 1.0 0.83 9.5 0.0 2.3 3 0 0 3 3 2 0 Domain of unknown function (DUF3357) Herpes_UL1 PF05259.6 KEY73604.1 - 0.12 11.8 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein L Gly-zipper_Omp PF13488.1 KEY73606.1 - 0.012 15.2 4.3 0.025 14.2 3.0 1.5 1 0 0 1 1 1 0 Glycine zipper API5 PF05918.6 KEY73616.1 - 5.7 5.3 10.1 4.7 5.5 0.1 2.1 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) DDE_Tnp_1_7 PF13843.1 KEY73617.1 - 4.7e-47 160.7 0.0 6.4e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 Zn_clus PF00172.13 KEY73620.1 - 1.9e-09 37.2 6.7 1.9e-09 37.2 4.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY73620.1 - 0.0021 16.9 1.3 0.0021 16.9 0.9 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain MBOAT_2 PF13813.1 KEY73623.1 - 2.4e-21 75.5 0.5 2.4e-21 75.5 0.3 1.6 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family p450 PF00067.17 KEY73624.1 - 2.7e-57 194.3 0.0 3.4e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 KEY73625.1 - 1.5e-15 57.5 0.2 3e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY73625.1 - 1.8e-06 27.7 0.1 2.9e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY73625.1 - 9e-05 22.0 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KEY73625.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MFS_1 PF07690.11 KEY73626.1 - 1.1e-27 96.6 42.2 1.7e-23 82.9 17.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_2 PF04909.9 KEY73627.1 - 4.8e-25 88.6 2.7 5.7e-25 88.4 1.9 1.1 1 0 0 1 1 1 1 Amidohydrolase p450 PF00067.17 KEY73628.1 - 3.5e-66 223.6 0.0 4.4e-66 223.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cupin_2 PF07883.6 KEY73629.1 - 0.037 13.5 1.0 0.057 12.9 0.3 1.6 2 0 0 2 2 2 0 Cupin domain Cupin_3 PF05899.7 KEY73629.1 - 0.11 11.9 0.1 0.32 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF861) FAD_binding_4 PF01565.18 KEY73630.1 - 9.8e-26 89.8 0.2 1.9e-25 88.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain CTP_transf_1 PF01148.15 KEY73631.1 - 2.6e-80 269.8 29.8 3.1e-80 269.5 20.6 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Amidase PF01425.16 KEY73632.1 - 2.6e-72 244.0 0.0 3.3e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.11 KEY73633.1 - 7.8e-41 139.9 29.3 7.8e-41 139.9 20.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY73633.1 - 3.5e-17 62.1 11.3 3.5e-17 62.1 7.8 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KEY73633.1 - 2.1e-06 26.2 5.7 3.2e-06 25.6 4.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KEY73633.1 - 0.0046 16.7 1.9 0.21 11.4 0.4 2.7 2 0 0 2 2 2 1 MFS_1 like family DUF1957 PF09210.6 KEY73633.1 - 0.18 11.9 0.2 0.31 11.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1957) WD40 PF00400.27 KEY73634.1 - 9.7e-12 44.2 5.5 4.8e-05 23.0 0.0 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat PGAP1 PF07819.8 KEY73634.1 - 1e-05 25.2 0.1 0.00014 21.5 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KEY73634.1 - 0.00017 21.5 0.0 0.00051 19.9 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KEY73634.1 - 0.0011 18.3 0.0 0.0026 17.0 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) BBS2_Mid PF14783.1 KEY73634.1 - 0.015 15.0 0.0 8.4 6.2 0.0 3.6 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region AAA_16 PF13191.1 KEY73634.1 - 0.024 14.6 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Fructosamin_kin PF03881.9 KEY73635.1 - 4.4e-35 121.0 2.6 6.2e-35 120.5 1.8 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KEY73635.1 - 0.0007 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family SnoaL PF07366.7 KEY73636.1 - 0.0058 16.2 0.1 0.013 15.0 0.1 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KEY73636.1 - 0.044 14.1 0.1 0.12 12.7 0.0 1.8 2 0 0 2 2 2 0 SnoaL-like domain DHDPS PF00701.17 KEY73637.1 - 1.1e-42 145.6 0.0 1.2e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family TFR_dimer PF04253.10 KEY73638.1 - 2.2e-18 66.0 0.0 4.1e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KEY73638.1 - 8.1e-17 61.5 0.0 1.5e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KEY73638.1 - 3.9e-05 23.2 0.4 0.00019 21.0 0.0 2.3 3 0 0 3 3 3 1 PA domain Peptidase_M20 PF01546.23 KEY73638.1 - 0.00094 18.7 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 KEY73638.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Nicastrin TPR_12 PF13424.1 KEY73639.1 - 8.9e-06 25.5 0.0 1.3e-05 25.0 0.0 1.3 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEY73639.1 - 0.0004 20.0 0.3 0.001 18.8 0.1 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 KEY73639.1 - 0.0012 18.6 0.8 0.0012 18.6 0.6 1.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEY73639.1 - 0.0019 17.7 0.0 0.0068 15.9 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEY73639.1 - 0.0058 16.3 0.1 0.012 15.4 0.1 1.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEY73639.1 - 0.0058 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEY73639.1 - 0.062 12.9 0.0 0.088 12.4 0.0 1.3 1 1 0 1 1 1 0 TPR repeat Retrotrans_gag PF03732.12 KEY73641.1 - 1.7e-09 37.5 0.3 1.7e-09 37.5 0.2 2.9 2 1 0 2 2 2 1 Retrotransposon gag protein Apolipoprotein PF01442.13 KEY73641.1 - 8.2e-05 22.2 9.4 0.0002 20.9 4.2 2.5 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain FH2 PF02181.18 KEY73641.1 - 0.016 14.1 1.9 0.029 13.2 1.3 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain FUSC PF04632.7 KEY73641.1 - 0.18 10.1 5.2 0.27 9.5 2.4 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family Syntaxin PF00804.20 KEY73641.1 - 0.2 11.8 5.7 0.085 13.0 1.6 2.1 2 0 0 2 2 2 0 Syntaxin Synaptobrevin PF00957.16 KEY73641.1 - 4.1 7.0 6.0 16 5.1 3.7 2.1 1 1 1 2 2 2 0 Synaptobrevin DUF972 PF06156.8 KEY73641.1 - 5.7 7.3 11.9 1.5 9.1 4.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF972) TPR_10 PF13374.1 KEY73642.1 - 4e-49 163.2 0.1 1.6e-10 40.5 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 KEY73642.1 - 4e-40 135.6 0.0 9e-14 51.1 0.0 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEY73642.1 - 5.3e-16 57.0 0.1 0.015 15.0 0.0 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 KEY73642.1 - 3.1e-10 39.4 0.3 0.22 11.7 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEY73642.1 - 5.5e-08 32.1 0.1 0.34 10.9 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEY73642.1 - 4.6e-07 29.1 0.0 2.9 7.6 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 KEY73642.1 - 5e-07 29.5 0.0 4 8.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEY73642.1 - 1.2e-06 28.6 1.2 6.6 7.6 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEY73642.1 - 4.6e-06 26.1 0.4 0.6 9.7 0.0 3.7 1 1 4 5 5 5 3 TPR repeat TPR_16 PF13432.1 KEY73642.1 - 1.7e-05 25.3 0.0 1.4 9.6 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEY73642.1 - 0.00016 21.9 0.1 3.2 8.1 0.1 4.0 1 1 3 4 4 4 1 Tetratricopeptide repeat DUF2664 PF10867.3 KEY73642.1 - 0.00041 20.9 1.0 1.5 9.4 0.1 4.1 3 2 2 5 5 5 1 Protein of unknown function (DUF2664) TPR_8 PF13181.1 KEY73642.1 - 0.0006 19.4 0.0 2 8.3 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Rab5-bind PF09311.6 KEY73642.1 - 0.00085 19.2 0.2 3 7.6 0.1 3.1 1 1 3 4 4 4 2 Rabaptin-like protein PPR_3 PF13812.1 KEY73642.1 - 0.006 16.7 0.4 21 5.7 0.0 3.7 4 0 0 4 4 4 0 Pentatricopeptide repeat domain TPR_6 PF13174.1 KEY73642.1 - 0.017 15.5 1.6 22 5.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 KEY73642.1 - 0.018 15.1 0.8 2 8.5 0.1 3.2 1 1 1 3 3 3 0 Tetratricopeptide repeat Euplotes_phero PF05842.6 KEY73642.1 - 0.039 14.3 0.1 1.3e+02 2.8 0.0 3.6 1 1 3 4 4 4 0 Euplotes octocarinatus mating pheromone protein Chibby PF14645.1 KEY73642.1 - 0.082 12.8 0.7 0.54 10.1 0.0 2.4 1 1 2 3 3 3 0 Chibby family FB_lectin PF07367.6 KEY73642.1 - 0.31 10.6 1.8 7.9 6.0 1.3 2.7 1 1 0 1 1 1 0 Fungal fruit body lectin TPR_10 PF13374.1 KEY73644.1 - 6.6e-34 114.8 0.0 1e-12 47.5 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEY73644.1 - 8.6e-28 96.1 0.0 5.4e-15 55.0 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEY73644.1 - 7.2e-12 44.1 0.2 0.0022 17.6 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEY73644.1 - 2.2e-10 39.8 0.1 0.063 13.5 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEY73644.1 - 6.9e-06 25.4 0.4 0.41 10.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEY73644.1 - 1.3e-05 24.7 0.2 0.034 13.7 0.0 2.7 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KEY73644.1 - 5.1e-05 22.8 0.0 0.76 9.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEY73644.1 - 0.00033 20.9 0.2 0.9 9.9 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.2 KEY73644.1 - 0.00084 19.3 0.2 1.1 9.3 0.0 2.2 1 1 1 2 2 2 2 Tetratrico peptide repeat TPR_14 PF13428.1 KEY73644.1 - 0.0018 18.7 0.4 6.5 7.6 0.0 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 KEY73644.1 - 0.003 17.8 0.0 4.9 7.8 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEY73644.1 - 0.0041 17.7 0.1 1.2 9.9 0.0 2.8 1 1 3 4 4 4 2 Tetratricopeptide repeat Euplotes_phero PF05842.6 KEY73644.1 - 0.0045 17.3 0.6 2.1 8.7 0.2 2.9 1 1 2 3 3 3 1 Euplotes octocarinatus mating pheromone protein TPR_8 PF13181.1 KEY73644.1 - 0.0071 16.0 0.1 6.8 6.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEY73644.1 - 0.0093 16.3 0.9 18 6.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat S100PBPR PF15427.1 KEY73644.1 - 0.028 13.4 0.4 8.9 5.2 0.1 2.8 1 1 2 3 3 3 0 S100P-binding protein SLD3 PF08639.5 KEY73644.1 - 0.03 12.9 0.6 0.035 12.7 0.4 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 PPR_3 PF13812.1 KEY73644.1 - 0.031 14.5 0.1 14 6.2 0.0 2.8 3 0 0 3 3 2 0 Pentatricopeptide repeat domain TPR_20 PF14561.1 KEY73644.1 - 0.039 14.0 0.4 1.6 8.8 0.0 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat Chibby PF14645.1 KEY73644.1 - 0.07 13.0 0.1 0.84 9.5 0.0 2.3 1 1 1 2 2 2 0 Chibby family Dimer_Tnp_Tn5 PF02281.11 KEY73644.1 - 0.08 13.0 1.0 5.2 7.2 0.1 2.6 1 1 2 3 3 3 0 Transposase Tn5 dimerisation domain SH3_8 PF13457.1 KEY73644.1 - 0.18 11.9 1.6 23 5.2 0.0 3.0 3 0 0 3 3 3 0 SH3-like domain DDE_Tnp_1_7 PF13843.1 KEY73645.1 - 5.3e-31 107.9 0.0 2.3e-16 59.7 0.0 2.7 2 1 0 2 2 2 2 Transposase IS4 Beta-lactamase PF00144.19 KEY73646.1 - 1.1e-45 156.1 0.1 1.5e-45 155.7 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.1 KEY73646.1 - 0.013 14.9 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 0 Beta-lactamase enzyme family PhyH PF05721.8 KEY73647.1 - 4.6e-16 59.5 0.1 6.9e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 KEY73647.1 - 0.049 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase MFS_1 PF07690.11 KEY73648.1 - 1.7e-19 69.7 45.2 1.7e-19 69.7 31.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KEY73648.1 - 6.9e-07 27.8 13.4 1e-06 27.2 9.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3817 PF12823.2 KEY73648.1 - 0.077 13.4 0.2 0.077 13.4 0.1 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF3817) ATP_transf PF09830.4 KEY73652.1 - 4.9e-15 55.0 0.0 1.8e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 ATP adenylyltransferase Zot PF05707.7 KEY73652.1 - 0.034 13.6 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Abhydrolase_3 PF07859.8 KEY73655.1 - 9.2e-25 87.4 0.0 1.2e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KEY73655.1 - 2.7e-09 36.1 0.0 8.8e-08 31.1 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KEY73655.1 - 0.0016 18.1 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KEY73655.1 - 0.022 13.5 0.0 0.047 12.4 0.0 1.5 1 1 0 1 1 1 0 Carboxylesterase family FAD_binding_3 PF01494.14 KEY73656.1 - 3.6e-29 101.9 0.0 4.8e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEY73656.1 - 4.1e-08 32.5 0.2 0.00011 21.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY73656.1 - 0.00022 21.2 0.0 0.00056 19.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEY73656.1 - 0.0032 16.3 0.2 0.015 14.1 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KEY73656.1 - 0.0053 17.1 0.2 0.03 14.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEY73656.1 - 0.007 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KEY73656.1 - 0.011 15.6 0.3 0.031 14.1 0.2 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KEY73656.1 - 0.019 15.0 0.0 0.052 13.6 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 KEY73656.1 - 0.074 11.5 0.0 0.13 10.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 KEY73656.1 - 0.1 11.2 0.2 3.6 6.1 0.0 2.4 2 1 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.13 KEY73656.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HELP PF03451.9 KEY73657.1 - 0.011 15.2 0.2 0.024 14.1 0.1 1.5 1 0 0 1 1 1 0 HELP motif DNA_PPF PF02916.10 KEY73657.1 - 0.069 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase processivity factor Baculo_PEP_C PF04513.7 KEY73658.1 - 0.027 14.3 6.5 0.051 13.4 4.5 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MFS_1 PF07690.11 KEY73659.1 - 2.7e-38 131.5 28.4 4.4e-37 127.6 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily V_ATPase_I PF01496.14 KEY73659.1 - 0.12 10.1 0.0 0.3 8.8 0.0 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Pmp3 PF01679.12 KEY73660.1 - 2.6e-11 43.0 6.7 3.3e-11 42.6 4.7 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF1656 PF07869.7 KEY73660.1 - 0.27 11.0 5.3 0.4 10.4 2.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) p450 PF00067.17 KEY73661.1 - 7.5e-28 97.2 0.0 1e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BRX PF08381.6 KEY73661.1 - 0.058 12.4 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 GFO_IDH_MocA PF01408.17 KEY73662.1 - 7.6e-19 68.4 0.0 1.2e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold MMS22L_N PF14910.1 KEY73662.1 - 0.15 10.3 0.1 0.2 9.8 0.0 1.1 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal Abhydrolase_6 PF12697.2 KEY73663.1 - 1.3e-16 61.1 0.0 1.6e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY73663.1 - 4.4e-07 29.7 0.0 6e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY73663.1 - 1.4e-06 28.0 0.0 1.8e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Polysacc_deac_1 PF01522.16 KEY73664.1 - 1e-26 92.9 0.0 1.3e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 KEY73664.1 - 0.048 12.5 0.0 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 p450 PF00067.17 KEY73665.1 - 2.6e-53 181.1 0.0 3.4e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Antimicrobial10 PF08105.6 KEY73665.1 - 0.0021 17.6 0.4 0.39 10.3 0.0 2.7 2 0 0 2 2 2 2 Metchnikowin family DUF1275 PF06912.6 KEY73666.1 - 6.2e-39 133.3 13.3 7.8e-39 133.0 9.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4229 PF14012.1 KEY73666.1 - 0.083 12.8 0.3 0.083 12.8 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) Oxidored_FMN PF00724.15 KEY73667.1 - 4.4e-35 121.2 0.0 3.1e-26 92.1 0.0 2.2 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans PF04082.13 KEY73668.1 - 6.8e-13 48.0 0.2 1e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY73668.1 - 2.3e-05 24.2 11.3 4.5e-05 23.2 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4463 PF14703.1 KEY73668.1 - 0.13 12.7 0.3 14 6.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) HAMP PF00672.20 KEY73668.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 HAMP domain Glyco_transf_34 PF05637.7 KEY73669.1 - 3e-07 30.1 0.2 6.9e-07 29.0 0.2 1.7 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.11 KEY73669.1 - 6.4e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Sugar_tr PF00083.19 KEY73670.1 - 7.7e-83 278.5 24.3 9e-83 278.3 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY73670.1 - 8.1e-25 87.2 49.3 6e-21 74.5 16.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KEY73670.1 - 4.1e-07 28.4 0.2 0.011 13.8 0.0 2.5 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Cupin_2 PF07883.6 KEY73671.1 - 0.00014 21.3 0.3 0.00027 20.3 0.2 1.6 1 1 0 1 1 1 1 Cupin domain NAD_binding_8 PF13450.1 KEY73672.1 - 9.3e-12 44.8 0.1 2.4e-11 43.4 0.0 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEY73672.1 - 1.2e-07 31.9 0.0 2.7e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEY73672.1 - 1.7e-06 27.1 0.8 2.9e-06 26.4 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KEY73672.1 - 3.4e-06 25.7 0.6 5.7e-06 25.0 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.19 KEY73672.1 - 9e-06 25.0 0.0 2.4e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 KEY73672.1 - 1.6e-05 24.1 0.0 2.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEY73672.1 - 2.7e-05 23.2 0.1 0.00012 21.0 0.0 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KEY73672.1 - 2.7e-05 23.4 0.0 4.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KEY73672.1 - 8.1e-05 21.8 0.3 0.00015 20.9 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KEY73672.1 - 0.00013 21.9 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEY73672.1 - 0.0034 17.1 0.3 0.025 14.3 0.0 2.3 1 1 1 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.17 KEY73672.1 - 0.0053 15.6 0.1 0.008 15.0 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KEY73672.1 - 0.022 15.1 0.0 0.13 12.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY73672.1 - 0.038 12.9 0.0 0.065 12.1 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Med25_SD1 PF11235.3 KEY73672.1 - 0.051 13.8 0.1 0.097 12.9 0.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 NAD_Gly3P_dh_N PF01210.18 KEY73672.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.16 KEY73672.1 - 0.072 12.6 0.1 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 KEY73672.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain UDPGT PF00201.13 KEY73674.1 - 3e-08 32.6 0.0 4e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ADH_zinc_N_2 PF13602.1 KEY73675.1 - 8.4e-21 75.1 0.2 8.4e-21 75.1 0.1 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KEY73675.1 - 1.3e-14 53.9 3.7 3.6e-14 52.4 0.4 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY73675.1 - 4.5e-09 36.0 2.1 1.8e-07 30.8 0.0 3.2 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KEY73675.1 - 0.0031 17.0 0.4 0.0056 16.2 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DOT1 PF08123.8 KEY73675.1 - 0.011 15.0 0.2 0.017 14.4 0.2 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 RmlD_sub_bind PF04321.12 KEY73675.1 - 0.025 13.5 0.1 0.044 12.6 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain HSP20 PF00011.16 KEY73676.1 - 5.6e-15 55.0 0.1 1.5e-09 37.6 0.0 2.4 2 1 0 2 2 2 2 Hsp20/alpha crystallin family SIT PF15330.1 KEY73676.1 - 4.8 7.3 5.8 19 5.4 0.0 2.6 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Zip PF02535.17 KEY73677.1 - 3.4e-44 151.1 0.1 5.7e-44 150.4 0.1 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter Actin PF00022.14 KEY73679.1 - 6.4e-101 337.6 0.0 8e-101 337.2 0.0 1.0 1 0 0 1 1 1 1 Actin Aldo_ket_red PF00248.16 KEY73680.1 - 3e-52 177.2 0.0 3.8e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DnaJ PF00226.26 KEY73681.1 - 8.1e-20 70.3 0.5 8.1e-20 70.3 0.3 2.9 4 0 0 4 4 4 1 DnaJ domain Beta-lactamase PF00144.19 KEY73682.1 - 2.3e-26 92.5 0.6 4.3e-26 91.7 0.4 1.4 1 0 0 1 1 1 1 Beta-lactamase DUF4330 PF14221.1 KEY73683.1 - 2.2 8.1 6.6 13 5.5 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4330) DUF996 PF06195.8 KEY73683.1 - 9.5 6.2 15.3 0.55 10.2 3.2 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF996) HET PF06985.6 KEY73684.1 - 4.5e-08 33.3 0.0 2e-05 24.8 0.0 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Apolipoprotein PF01442.13 KEY73685.1 - 0.00011 21.7 5.5 0.00022 20.7 3.8 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF725 PF05267.7 KEY73685.1 - 0.035 14.0 0.7 0.078 12.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF725) CagA PF03507.8 KEY73685.1 - 0.082 12.7 0.2 6.8 6.4 0.0 2.3 1 1 1 2 2 2 0 CagA exotoxin Prominin PF05478.6 KEY73685.1 - 0.11 9.9 1.2 0.15 9.5 0.8 1.1 1 0 0 1 1 1 0 Prominin DUF883 PF05957.8 KEY73685.1 - 3.1 8.2 6.6 3.5 8.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3446 PF11928.3 KEY73685.1 - 9.1 6.5 9.4 0.7 10.1 2.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) DDE_Tnp_1_7 PF13843.1 KEY73686.1 - 2.1e-05 23.7 0.2 4e-05 22.8 0.0 1.5 2 0 0 2 2 2 1 Transposase IS4 Pkinase PF00069.20 KEY73687.1 - 0.0092 15.1 0.0 0.016 14.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY73687.1 - 0.012 14.6 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase SEN1_N PF12726.2 KEY73692.1 - 0.0079 14.3 0.0 0.012 13.7 0.0 1.2 1 0 0 1 1 1 1 SEN1 N terminal bZIP_1 PF00170.16 KEY73693.1 - 2e-05 24.4 10.6 3.2e-05 23.8 7.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor Phage_GP20 PF06810.6 KEY73693.1 - 0.0038 16.6 2.1 0.0052 16.2 1.3 1.3 1 1 0 1 1 1 1 Phage minor structural protein GP20 SlyX PF04102.7 KEY73693.1 - 0.038 14.3 0.0 0.083 13.2 0.0 1.5 1 0 0 1 1 1 0 SlyX Herpes_UL6 PF01763.11 KEY73693.1 - 0.072 11.2 0.1 0.075 11.1 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like ATG16 PF08614.6 KEY73693.1 - 0.093 12.5 8.5 0.17 11.7 5.9 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Lipoprotein_6 PF01441.14 KEY73693.1 - 0.12 12.2 0.8 0.17 11.7 0.5 1.2 1 0 0 1 1 1 0 Lipoprotein DUF641 PF04859.7 KEY73693.1 - 0.16 11.7 3.2 0.25 11.0 2.2 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF3584 PF12128.3 KEY73693.1 - 0.19 9.0 4.6 0.22 8.7 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HAUS6_N PF14661.1 KEY73693.1 - 0.2 10.9 3.0 0.27 10.5 2.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus COG5 PF10392.4 KEY73693.1 - 0.27 11.2 3.7 0.39 10.6 2.6 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Mitofilin PF09731.4 KEY73693.1 - 0.34 9.4 7.8 0.41 9.2 5.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4404 PF14357.1 KEY73693.1 - 0.87 10.0 6.3 0.28 11.6 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DivIC PF04977.10 KEY73693.1 - 1.1 8.7 6.9 0.19 11.2 1.4 1.9 1 1 1 2 2 2 0 Septum formation initiator bZIP_2 PF07716.10 KEY73693.1 - 1.7 8.5 14.0 2.7 7.8 9.7 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Atg14 PF10186.4 KEY73693.1 - 2.8 6.8 8.9 4.1 6.2 6.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KEY73693.1 - 7.6 6.0 8.5 8.6 5.9 5.0 1.4 1 1 0 1 1 1 0 IncA protein DUF3435 PF11917.3 KEY73695.1 - 2.7e-60 204.2 0.3 9.7e-60 202.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) HTH_Tnp_Tc5 PF03221.11 KEY73695.1 - 1.9e-07 30.7 0.0 7.4e-07 28.8 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 KEY73695.1 - 0.00085 18.5 0.1 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Val_tRNA-synt_C PF10458.4 KEY73695.1 - 0.7 10.0 7.1 0.64 10.1 0.6 3.8 4 0 0 4 4 4 0 Valyl tRNA synthetase tRNA binding arm Methyltransf_2 PF00891.13 KEY73696.1 - 4.7e-27 94.7 0.0 6.7e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_PK PF05891.7 KEY73696.1 - 0.03 13.6 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Glyco_transf_34 PF05637.7 KEY73697.1 - 2.2e-15 56.8 0.1 1.1e-14 54.5 0.1 1.9 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glyco_transf_8 PF01501.15 KEY73697.1 - 0.011 15.0 0.1 0.028 13.7 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 8 PSD4 PF07631.6 KEY73697.1 - 0.026 14.8 0.4 2.5 8.4 0.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1592) Glyco_hydro_61 PF03443.9 KEY73698.1 - 4.6e-38 131.2 0.0 6.3e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF3450 PF11932.3 KEY73699.1 - 1.3e-05 24.5 0.2 1.7e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF4200 PF13863.1 KEY73699.1 - 0.0022 17.9 0.5 0.0033 17.3 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.4 KEY73699.1 - 0.0038 17.0 2.0 0.0056 16.5 1.4 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 KEY73699.1 - 0.0074 15.7 0.9 0.011 15.1 0.6 1.3 1 0 0 1 1 1 1 Septum formation initiator Sipho_Gp157 PF05565.6 KEY73699.1 - 0.034 13.7 0.1 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 ATG16 PF08614.6 KEY73699.1 - 0.044 13.6 0.9 0.058 13.2 0.6 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Med4 PF10018.4 KEY73699.1 - 0.098 12.0 0.3 0.14 11.5 0.2 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4140 PF13600.1 KEY73699.1 - 0.2 12.0 2.2 0.26 11.7 1.2 1.5 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 KEY73699.1 - 0.53 9.8 2.8 0.68 9.5 2.0 1.1 1 0 0 1 1 1 0 IncA protein UVR PF02151.14 KEY73699.1 - 1.2 8.7 4.0 0.61 9.6 0.5 2.1 2 1 1 3 3 3 0 UvrB/uvrC motif Cortex-I_coil PF09304.5 KEY73700.1 - 0.011 15.8 2.9 0.2 11.7 0.1 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF1002 PF06207.6 KEY73700.1 - 0.02 14.1 0.2 0.023 14.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) DUF1409 PF07197.7 KEY73700.1 - 0.028 14.4 2.1 0.069 13.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) Streptin-Immun PF11083.3 KEY73700.1 - 0.032 14.2 0.5 0.046 13.7 0.3 1.2 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein Phage_GPO PF05929.6 KEY73700.1 - 0.048 12.9 0.8 0.057 12.6 0.5 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Dynactin_p22 PF07426.6 KEY73700.1 - 0.062 12.5 0.8 0.089 12.0 0.6 1.3 1 0 0 1 1 1 0 Dynactin subunit p22 DUF342 PF03961.8 KEY73700.1 - 0.07 11.5 0.1 0.082 11.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FliJ PF02050.11 KEY73700.1 - 0.086 12.8 1.5 0.12 12.3 1.0 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein AATF-Che1 PF13339.1 KEY73700.1 - 0.51 10.4 3.6 2.5 8.2 2.5 1.9 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Methyltransf_3 PF01596.12 KEY73702.1 - 1.1e-27 96.4 0.0 2.4e-27 95.3 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 KEY73702.1 - 5.3e-13 49.7 0.0 1.5e-12 48.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KEY73702.1 - 1.2e-08 34.8 0.0 1.5e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KEY73702.1 - 6.4e-07 29.9 0.0 1e-06 29.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY73702.1 - 2.5e-06 27.1 0.0 3.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY73702.1 - 7.5e-05 22.7 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY73702.1 - 0.011 16.0 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KEY73702.1 - 0.043 14.2 0.0 0.083 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SUR7 PF06687.7 KEY73703.1 - 1.3e-19 70.6 13.0 1.8e-19 70.2 9.0 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KEY73703.1 - 0.00023 20.9 9.8 0.00023 20.9 6.8 2.3 1 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Shisa PF13908.1 KEY73703.1 - 0.0064 16.6 3.5 0.0068 16.6 0.1 2.2 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 KEY73703.1 - 0.012 16.0 4.6 0.085 13.2 0.0 3.1 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.3 KEY73703.1 - 0.027 15.0 3.4 0.042 14.4 0.7 2.2 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Protocadherin PF08374.6 KEY73703.1 - 0.12 12.0 1.9 0.16 11.5 0.0 2.0 1 1 1 2 2 2 0 Protocadherin DUF3377 PF11857.3 KEY73703.1 - 0.19 11.4 0.1 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) CD34_antigen PF06365.7 KEY73703.1 - 0.21 11.2 1.6 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 CD34/Podocalyxin family DUF1628 PF07790.6 KEY73703.1 - 0.33 11.7 4.7 14 6.5 1.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1628) DUF805 PF05656.9 KEY73703.1 - 0.63 9.8 7.5 0.11 12.3 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF805) SieB PF14163.1 KEY73703.1 - 1.2 8.6 0.0 1.2 8.6 0.0 2.6 2 1 1 3 3 3 0 Superinfection exclusion protein B PLAC8 PF04749.12 KEY73703.1 - 1.4 9.4 6.3 0.52 10.9 1.7 2.1 1 1 1 2 2 2 0 PLAC8 family Trp_oprn_chp PF09534.5 KEY73703.1 - 1.5 8.4 10.7 0.27 10.8 2.4 2.4 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Herpes_gE PF02480.11 KEY73703.1 - 1.5 6.9 8.3 0.075 11.2 1.2 2.0 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E MARVEL PF01284.18 KEY73703.1 - 1.6 8.5 14.7 8.6 6.1 8.1 2.9 2 1 0 2 2 2 0 Membrane-associating domain Med1 PF10744.4 KEY73705.1 - 8.8e-37 126.7 0.0 3.9e-36 124.6 0.0 1.8 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 DLH PF01738.13 KEY73707.1 - 1e-27 96.8 0.0 1.3e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KEY73707.1 - 1.3e-07 31.5 0.0 1.9e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KEY73707.1 - 0.00064 19.4 0.0 0.097 12.3 0.0 2.2 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 KEY73707.1 - 0.014 14.6 0.0 0.72 9.0 0.0 2.1 1 1 1 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KEY73707.1 - 0.087 12.3 0.0 0.49 9.9 0.0 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold Formyl_trans_N PF00551.14 KEY73708.1 - 3.1e-23 82.2 0.0 4.9e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 KEY73708.1 - 1.7e-07 31.2 0.0 3.5e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain DUF3405 PF11885.3 KEY73710.1 - 1.7e-176 587.3 5.8 2.2e-176 586.9 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) YflT PF11181.3 KEY73710.1 - 0.15 12.2 0.0 0.65 10.1 0.0 1.9 2 0 0 2 2 2 0 Heat induced stress protein YflT LIM PF00412.17 KEY73711.1 - 3.6e-22 78.1 14.9 2.2e-11 43.6 2.3 2.6 3 0 0 3 3 3 2 LIM domain NAD_binding_5 PF07994.7 KEY73712.1 - 4.6e-114 380.8 0.4 4.6e-114 380.8 0.3 1.8 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 KEY73712.1 - 1.4e-44 150.5 0.4 4.2e-44 148.9 0.3 1.9 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase MRC1 PF09444.5 KEY73712.1 - 1.1e-41 142.5 16.6 1.1e-41 142.5 11.5 5.5 5 1 1 6 6 6 1 MRC1-like domain Asn_synthase PF00733.16 KEY73713.1 - 1.6e-69 234.2 0.0 2.2e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase UQ_con PF00179.21 KEY73713.1 - 7.5e-45 151.8 0.0 1.5e-44 150.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme GATase_7 PF13537.1 KEY73713.1 - 3e-36 123.9 0.0 4.6e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KEY73713.1 - 3.1e-28 98.3 0.0 1e-27 96.6 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KEY73713.1 - 2.4e-09 36.7 0.1 4.3e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 KEY73713.1 - 0.0012 17.8 0.0 0.0023 16.8 0.0 1.6 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 KEY73713.1 - 0.0017 17.1 0.0 0.01 14.6 0.0 1.9 1 1 1 2 2 2 1 Glutamine amidotransferases class-II Prok-E2_B PF14461.1 KEY73713.1 - 0.0026 17.4 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KEY73713.1 - 0.13 12.1 0.1 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 RWD domain Pex19 PF04614.7 KEY73714.1 - 1.9e-72 243.8 16.0 3e-72 243.2 11.1 1.3 1 0 0 1 1 1 1 Pex19 protein family Asp-B-Hydro_N PF05279.6 KEY73714.1 - 0.017 15.0 0.4 0.017 15.0 0.3 2.3 2 1 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Glyco_transf_15 PF01793.11 KEY73714.1 - 0.02 13.8 0.3 0.032 13.1 0.2 1.3 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase FliE PF02049.13 KEY73714.1 - 0.28 11.2 9.1 1.8 8.6 1.3 3.5 1 1 1 3 3 3 0 Flagellar hook-basal body complex protein FliE ABC1 PF03109.11 KEY73716.1 - 4.6e-32 110.4 0.1 7.8e-32 109.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family UCR_Fe-S_N PF10399.4 KEY73716.1 - 0.045 12.9 2.4 0.12 11.6 1.7 1.7 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Porin_3 PF01459.17 KEY73717.1 - 2.3e-60 204.1 4.4 6.7e-60 202.7 3.1 1.6 1 1 0 1 1 1 1 Eukaryotic porin DnaJ PF00226.26 KEY73718.1 - 6.4e-18 64.2 0.8 1e-17 63.5 0.6 1.3 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.13 KEY73719.1 - 7.6e-34 116.7 0.0 1.6e-33 115.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY73719.1 - 4.9e-10 39.1 11.4 8.5e-10 38.3 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3343 PF11823.3 KEY73719.1 - 0.028 13.6 0.0 0.096 11.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) CCDC-167 PF15188.1 KEY73719.1 - 0.57 10.1 3.2 0.57 10.1 0.9 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 SET PF00856.23 KEY73720.1 - 0.0021 18.4 0.0 0.46 10.7 0.0 2.4 2 0 0 2 2 2 2 SET domain MMR_HSR1_C PF08438.5 KEY73721.1 - 8.4e-31 106.4 0.0 7.1e-30 103.4 0.0 2.1 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 KEY73721.1 - 6e-15 55.2 0.0 1.8e-14 53.6 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEY73721.1 - 2.9e-06 26.6 0.1 0.00019 20.7 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KEY73721.1 - 0.0016 17.8 0.6 2.2 7.6 0.0 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KEY73721.1 - 0.0041 16.9 0.9 0.22 11.2 0.1 3.0 3 0 0 3 3 3 1 Dynamin family DUF356 PF04009.7 KEY73721.1 - 0.032 14.3 0.2 0.064 13.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF356) ATP_bind_1 PF03029.12 KEY73721.1 - 0.041 13.4 0.3 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 KEY73721.1 - 0.041 12.6 1.4 0.15 10.8 0.0 2.4 2 1 1 3 3 3 0 ArgK protein ABC_tran PF00005.22 KEY73721.1 - 0.091 13.0 0.0 0.38 11.0 0.0 1.9 2 0 0 2 2 2 0 ABC transporter F-box-like PF12937.2 KEY73722.1 - 1.5e-07 31.0 0.8 5.7e-07 29.1 0.5 2.1 2 0 0 2 2 2 1 F-box-like TPR_11 PF13414.1 KEY73722.1 - 2.3e-05 23.9 4.5 0.49 10.0 0.1 3.6 3 0 0 3 3 3 2 TPR repeat F-box PF00646.28 KEY73722.1 - 0.0057 16.2 0.7 0.016 14.8 0.1 2.0 2 0 0 2 2 2 1 F-box domain TPR_14 PF13428.1 KEY73722.1 - 0.0092 16.5 6.6 0.011 16.3 0.5 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEY73722.1 - 0.0095 15.5 1.0 4.4 7.0 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEY73722.1 - 0.016 15.8 1.5 0.016 15.8 1.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEY73722.1 - 0.027 14.3 1.9 0.48 10.4 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEY73722.1 - 0.074 12.9 7.1 5.3 7.2 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Aminotran_4 PF01063.14 KEY73723.1 - 5.2e-14 52.2 0.0 6.7e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV TPR_11 PF13414.1 KEY73724.1 - 1.6e-53 178.2 23.9 6.9e-13 48.0 0.3 7.0 4 2 4 8 8 8 8 TPR repeat TPR_1 PF00515.23 KEY73724.1 - 1.4e-46 154.2 17.7 7.1e-06 25.4 0.0 11.4 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.12 KEY73724.1 - 1.9e-44 146.0 16.7 5.2e-05 22.8 0.0 11.5 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_16 PF13432.1 KEY73724.1 - 8.7e-32 109.0 7.1 1.3e-07 32.0 0.1 6.5 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 KEY73724.1 - 7.1e-29 99.5 18.5 2.8e-07 30.3 0.0 7.3 2 2 5 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 KEY73724.1 - 2e-26 89.9 9.0 9.6e-05 22.2 0.0 9.7 10 1 0 10 10 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 KEY73724.1 - 3.9e-19 66.9 19.4 0.0029 17.2 0.0 9.9 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 KEY73724.1 - 1.9e-16 60.1 16.5 9.8e-06 25.8 0.1 6.8 5 1 3 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 KEY73724.1 - 1.1e-15 56.7 16.1 0.00014 22.1 0.1 9.4 3 3 8 11 11 11 3 Tetratricopeptide repeat TPR_9 PF13371.1 KEY73724.1 - 7.1e-12 45.0 8.3 0.044 13.6 0.1 6.3 3 2 4 7 7 7 4 Tetratricopeptide repeat Apc3 PF12895.2 KEY73724.1 - 5.9e-11 42.3 13.7 0.021 14.9 0.5 5.5 2 1 3 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KEY73724.1 - 8.6e-10 37.6 16.2 0.29 11.0 0.1 9.2 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_15 PF13429.1 KEY73724.1 - 6.6e-05 22.1 8.9 0.19 10.7 1.8 4.6 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEY73724.1 - 0.00013 22.2 23.8 3.1 8.4 0.0 9.5 11 0 0 11 11 9 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 KEY73724.1 - 0.0035 16.5 6.6 6.3 6.1 0.0 5.4 5 0 0 5 5 5 2 SHNi-TPR MAS20 PF02064.10 KEY73724.1 - 0.0094 15.8 2.7 30 4.5 0.0 4.6 5 0 0 5 5 5 0 MAS20 protein import receptor NARP1 PF12569.3 KEY73724.1 - 0.013 14.3 0.2 0.013 14.3 0.1 4.6 3 2 2 5 5 4 0 NMDA receptor-regulated protein 1 Coatomer_E PF04733.9 KEY73724.1 - 0.037 13.2 5.6 0.73 8.9 0.0 3.6 3 1 0 3 3 3 0 Coatomer epsilon subunit Sel1 PF08238.7 KEY73724.1 - 2.5 8.8 16.2 2.2 9.0 0.1 4.9 4 0 0 4 4 4 0 Sel1 repeat TPR_10 PF13374.1 KEY73724.1 - 9.8 6.2 15.1 7.3 6.6 0.6 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat SNARE PF05739.14 KEY73725.1 - 3.6e-14 52.1 3.1 1.2e-13 50.4 2.1 2.0 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 KEY73725.1 - 7.3e-11 42.1 2.8 7.3e-11 42.1 2.0 2.4 2 1 0 2 2 2 1 Syntaxin Use1 PF09753.4 KEY73725.1 - 0.00024 20.6 8.5 0.00036 20.0 5.8 1.3 1 1 0 1 1 1 1 Membrane fusion protein Use1 Bac_export_3 PF01313.14 KEY73725.1 - 0.018 14.6 0.3 0.034 13.8 0.2 1.3 1 0 0 1 1 1 0 Bacterial export proteins, family 3 Peptidase_C6 PF00851.13 KEY73725.1 - 0.02 13.5 3.4 0.014 14.0 1.0 1.6 1 1 1 2 2 2 0 Helper component proteinase Dispanin PF04505.7 KEY73725.1 - 0.044 13.3 0.4 0.11 12.0 0.1 1.7 2 0 0 2 2 2 0 Interferon-induced transmembrane protein Allexi_40kDa PF05549.6 KEY73725.1 - 0.26 10.5 9.3 0.074 12.3 1.6 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein Tweety PF04906.8 KEY73725.1 - 0.36 9.1 7.4 1.6 7.0 0.3 2.4 2 1 0 2 2 2 0 Tweety Brix PF04427.13 KEY73726.1 - 3.3e-46 157.3 0.1 4.1e-46 157.0 0.1 1.1 1 0 0 1 1 1 1 Brix domain UPF1_Zn_bind PF09416.5 KEY73727.1 - 4.2e-71 237.4 4.5 4.2e-71 237.4 3.1 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 KEY73727.1 - 1.6e-59 200.6 0.0 4.6e-59 199.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KEY73727.1 - 8.2e-57 192.4 2.2 1.2e-56 191.9 1.6 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEY73727.1 - 7.1e-15 54.5 0.3 1.8e-14 53.2 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KEY73727.1 - 2.1e-12 47.0 0.8 6.7e-11 42.1 0.5 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KEY73727.1 - 7.6e-08 32.3 0.0 1.5e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 KEY73727.1 - 0.00016 21.1 0.1 0.0039 16.5 0.1 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 KEY73727.1 - 0.00018 21.1 0.6 0.44 10.0 0.0 3.0 2 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 KEY73727.1 - 0.00019 20.9 0.5 0.00041 19.8 0.3 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase PIF1 PF05970.9 KEY73727.1 - 0.0002 20.4 0.5 0.17 10.8 0.1 2.3 1 1 1 2 2 2 2 PIF1-like helicase Helicase_RecD PF05127.9 KEY73727.1 - 0.00022 20.9 0.1 0.00065 19.3 0.0 1.9 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.4 KEY73727.1 - 0.0012 17.8 1.7 0.0031 16.5 0.1 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 KEY73727.1 - 0.0021 17.2 0.0 0.0098 15.0 0.0 1.9 2 0 0 2 2 2 1 KaiC Ribosomal_S13_N PF08069.7 KEY73727.1 - 0.0033 17.2 0.0 0.0098 15.7 0.0 1.8 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain AAA_25 PF13481.1 KEY73727.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KEY73727.1 - 0.027 13.7 0.1 0.068 12.3 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.1 KEY73727.1 - 0.031 14.2 0.1 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 KEY73727.1 - 0.033 13.0 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 KEY73727.1 - 0.042 13.2 0.0 0.081 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.17 KEY73727.1 - 0.084 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain UvrD_C_2 PF13538.1 KEY73727.1 - 0.13 12.3 0.0 0.4 10.8 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Glyco_hydro_47 PF01532.15 KEY73728.1 - 1.7e-157 524.7 0.0 1.9e-157 524.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GDPD PF03009.12 KEY73729.1 - 2.7e-30 105.7 0.0 1.2e-29 103.5 0.0 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 KEY73729.1 - 0.00068 19.7 2.3 0.14 12.4 0.1 2.8 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Plus-3 PF03126.13 KEY73730.1 - 2.6e-27 94.9 0.0 5.7e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 Plus-3 domain COQ7 PF03232.8 KEY73731.1 - 7.5e-65 217.5 0.1 8.9e-65 217.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 KEY73731.1 - 0.00057 20.2 0.2 0.0015 18.8 0.1 1.8 1 1 0 1 1 1 1 Rubrerythrin B12D PF06522.6 KEY73731.1 - 0.091 12.4 0.3 0.22 11.2 0.1 1.7 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit PLDc PF00614.17 KEY73732.1 - 2.5e-16 58.9 1.4 8.4e-08 31.7 0.4 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KEY73732.1 - 3.4e-13 49.4 0.2 1.8e-08 34.2 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 KEY73732.1 - 5.8e-07 29.3 0.1 3.6e-06 26.7 0.0 2.5 3 1 0 3 3 3 1 PX domain PH_2 PF08458.5 KEY73732.1 - 0.18 11.7 0.1 0.4 10.6 0.1 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region ERG4_ERG24 PF01222.12 KEY73733.1 - 6.5e-134 446.6 21.3 7.6e-134 446.4 14.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ATP-synt_C PF00137.16 KEY73734.1 - 1.6e-31 107.9 31.5 2e-18 66.0 8.7 2.0 2 0 0 2 2 2 2 ATP synthase subunit C ABA_GPCR PF12430.3 KEY73734.1 - 0.19 10.8 0.7 1.7 7.7 0.1 2.0 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor Flavi_NS4A PF01350.12 KEY73734.1 - 0.36 10.3 4.6 0.15 11.6 1.0 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A DUF2970 PF11174.3 KEY73734.1 - 7 6.3 10.2 1.1 8.9 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Ribosomal_L7Ae PF01248.21 KEY73735.1 - 7.7e-25 86.2 0.1 9.1e-25 86.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KEY73735.1 - 7.8e-05 22.5 0.0 9.2e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 CoaE PF01121.15 KEY73735.1 - 0.08 12.3 0.0 1.9 7.8 0.0 2.0 1 1 1 2 2 2 0 Dephospho-CoA kinase PELOTA_1 PF15608.1 KEY73735.1 - 0.09 12.5 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain Syja_N PF02383.13 KEY73736.1 - 8.2e-92 307.3 0.0 1.2e-91 306.8 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 KEY73736.1 - 6e-32 109.4 0.0 1.1e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase DUF3115 PF11312.3 KEY73737.1 - 4.7e-88 295.0 0.0 8.6e-88 294.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3115) Transketolase_N PF00456.16 KEY73738.1 - 8.2e-155 514.6 0.0 1.1e-154 514.2 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KEY73738.1 - 3.7e-43 147.0 0.0 6.1e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KEY73738.1 - 4.8e-12 45.9 0.0 9.8e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.16 KEY73738.1 - 0.0011 18.5 1.6 0.017 14.7 0.6 2.8 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Pas_Saposin PF09016.5 KEY73738.1 - 0.0028 17.6 0.0 0.0072 16.2 0.0 1.7 1 0 0 1 1 1 1 Pas factor saposin fold Btz PF09405.5 KEY73740.1 - 2.9e-28 98.4 2.7 5.8e-28 97.5 1.9 1.4 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding ZZ PF00569.12 KEY73741.1 - 3.1e-21 74.6 51.3 1.1e-06 28.0 5.6 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type Tubulin PF00091.20 KEY73742.1 - 2.4e-61 207.3 0.0 9.8e-61 205.3 0.0 1.9 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KEY73742.1 - 5.1e-45 152.5 0.1 8.7e-45 151.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Ran_BP1 PF00638.13 KEY73742.1 - 2.8e-09 37.0 0.0 6.7e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain UPF0160 PF03690.8 KEY73743.1 - 3.6e-122 407.7 0.0 4.1e-122 407.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Endosulfine PF04667.12 KEY73744.1 - 1.8e-20 72.6 0.0 3e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region GCS PF03074.11 KEY73745.1 - 1.4e-159 531.1 0.0 2.3e-159 530.3 0.0 1.3 1 1 0 1 1 1 1 Glutamate-cysteine ligase Helitron_like_N PF14214.1 KEY73747.1 - 0.05 13.3 0.7 0.088 12.5 0.5 1.4 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus Fcf1 PF04900.7 KEY73747.1 - 0.062 13.3 2.0 0.29 11.2 0.3 2.3 1 1 0 2 2 2 0 Fcf1 Alpha_kinase PF02816.13 KEY73747.1 - 0.099 12.2 3.1 0.14 11.7 2.0 1.3 1 1 0 1 1 1 0 Alpha-kinase family IncA PF04156.9 KEY73747.1 - 0.17 11.4 17.1 0.23 11.0 11.9 1.3 1 0 0 1 1 1 0 IncA protein FAM195 PF14799.1 KEY73747.1 - 0.18 11.7 3.2 0.34 10.7 2.2 1.5 1 0 0 1 1 1 0 FAM195 family Prefoldin_3 PF13758.1 KEY73747.1 - 0.27 11.0 9.0 0.052 13.3 2.6 2.2 1 1 1 2 2 2 0 Prefoldin subunit Smac_DIABLO PF09057.5 KEY73747.1 - 0.29 10.2 8.6 0.28 10.2 4.8 1.8 1 1 1 2 2 2 0 Second Mitochondria-derived Activator of Caspases Tox-HDC PF15656.1 KEY73747.1 - 0.49 10.6 3.6 2.4 8.3 0.1 2.6 2 1 0 2 2 2 0 Toxin with a H, D/N and C signature DUF1664 PF07889.7 KEY73747.1 - 1.1 9.0 8.7 0.49 10.1 0.5 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 KEY73747.1 - 1.4 9.2 14.7 0.54 10.6 5.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) RestrictionSfiI PF11487.3 KEY73747.1 - 1.9 7.6 6.7 0.65 9.1 1.0 2.0 1 1 1 2 2 2 0 Type II restriction enzyme SfiI FUSC PF04632.7 KEY73747.1 - 2.9 6.2 7.4 2.5 6.4 4.4 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family Jnk-SapK_ap_N PF09744.4 KEY73747.1 - 6.6 6.6 20.3 4.6 7.2 1.4 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Cep57_CLD_2 PF14197.1 KEY73747.1 - 7.2 6.6 17.1 5.8 6.9 1.6 2.7 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 FtsL PF04999.8 KEY73747.1 - 9.3 6.0 9.6 8.7 6.1 0.8 2.6 2 1 0 2 2 2 0 Cell division protein FtsL DUF4200 PF13863.1 KEY73747.1 - 9.5 6.1 29.9 0.78 9.6 14.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TATR PF03430.8 KEY73749.1 - 1 7.9 5.9 1.5 7.4 4.1 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF3723 PF12520.3 KEY73750.1 - 2.7e-12 45.9 0.4 4.8e-12 45.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3723) Reo_sigmaC PF04582.7 KEY73750.1 - 0.0091 15.2 1.1 0.012 14.8 0.7 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF3552 PF12072.3 KEY73750.1 - 0.067 12.3 10.5 0.1 11.8 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Spc7 PF08317.6 KEY73750.1 - 0.079 11.6 7.9 0.11 11.1 5.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2987 PF11205.3 KEY73750.1 - 0.086 12.5 1.2 0.14 11.8 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2987) HET PF06985.6 KEY73751.1 - 1e-11 45.1 4.6 5.3e-11 42.8 2.6 2.6 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) AAA_22 PF13401.1 KEY73755.1 - 9.5e-07 29.0 0.4 0.00038 20.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KEY73755.1 - 2.8e-06 27.1 0.6 0.0028 17.3 0.0 3.0 3 1 0 3 3 3 2 NACHT domain NB-ARC PF00931.17 KEY73755.1 - 0.00014 20.8 0.4 0.00049 19.0 0.3 1.8 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KEY73755.1 - 0.00061 19.8 7.3 0.0056 16.6 3.4 3.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 KEY73755.1 - 0.0027 17.5 0.0 0.0086 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KEY73755.1 - 0.0058 16.1 0.1 0.022 14.1 0.1 1.9 2 1 0 2 2 2 1 AAA-like domain Abhydrolase_6 PF12697.2 KEY73755.1 - 0.0062 16.4 0.0 0.022 14.6 0.0 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_2 PF12796.2 KEY73755.1 - 0.015 15.6 0.0 0.063 13.6 0.0 2.0 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Viral_helicase1 PF01443.13 KEY73755.1 - 0.023 14.2 0.0 0.06 12.8 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 KEY73755.1 - 0.036 14.3 0.1 0.11 12.8 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 KEY73755.1 - 0.044 14.6 0.0 0.25 12.1 0.0 2.4 2 0 0 2 2 1 0 AAA domain DUF676 PF05057.9 KEY73755.1 - 0.054 12.7 0.1 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_25 PF13481.1 KEY73755.1 - 0.057 12.8 0.0 0.16 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEY73755.1 - 0.057 13.5 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.1 KEY73755.1 - 0.07 13.4 6.1 0.52 10.5 4.3 2.4 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KEY73755.1 - 0.084 13.0 0.0 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Imm3 PF14425.1 KEY73756.1 - 0.027 14.4 0.0 0.067 13.1 0.0 1.6 2 0 0 2 2 2 0 Immunity protein Imm3 Pox_MCEL PF03291.11 KEY73756.1 - 0.065 12.0 0.1 0.082 11.7 0.1 1.1 1 0 0 1 1 1 0 mRNA capping enzyme Noggin PF05806.7 KEY73756.1 - 0.087 12.0 0.3 0.17 11.1 0.2 1.5 1 1 0 1 1 1 0 Noggin Cas_Cmr5 PF09701.5 KEY73757.1 - 0.0098 16.0 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cmr5) PhoU PF01895.14 KEY73757.1 - 0.04 14.3 0.1 0.08 13.3 0.1 1.5 1 0 0 1 1 1 0 PhoU domain Fungal_trans_2 PF11951.3 KEY73758.1 - 4.1e-23 81.6 2.5 5.8e-23 81.1 1.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DDE_Tnp_1_7 PF13843.1 KEY73758.1 - 2.1e-11 43.4 0.0 3.1e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Transposase IS4 adh_short PF00106.20 KEY73758.1 - 4.3e-10 39.7 0.6 1.3e-09 38.1 0.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KEY73758.1 - 2.4e-05 23.9 0.2 0.0013 18.1 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 KEY73758.1 - 0.005 16.8 0.1 0.0093 15.9 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 KEY73758.1 - 0.0056 16.3 0.1 0.015 14.9 0.1 1.7 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 KEY73758.1 - 0.034 13.4 0.1 0.057 12.6 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family TPR_10 PF13374.1 KEY73759.1 - 3.8e-25 87.0 0.2 4.2e-09 36.0 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEY73759.1 - 2e-17 62.9 0.1 3.1e-09 36.6 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 KEY73759.1 - 1e-14 54.1 0.1 1.7e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily TPR_7 PF13176.1 KEY73759.1 - 6.5e-06 25.5 0.1 0.43 10.4 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat NB-ARC PF00931.17 KEY73759.1 - 2.9e-05 23.0 0.0 0.00094 18.1 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.7 KEY73759.1 - 6.7e-05 22.5 0.0 0.00016 21.3 0.0 1.7 2 0 0 2 2 2 1 NACHT domain TPR_17 PF13431.1 KEY73759.1 - 0.0013 18.7 0.2 5.9 7.3 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEY73759.1 - 0.006 17.1 0.1 11 6.9 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEY73759.1 - 0.086 12.7 1.8 11 6.2 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KEY73759.1 - 0.67 10.5 4.1 67 4.3 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat p450 PF00067.17 KEY73760.1 - 8.8e-09 34.3 0.0 7.3e-06 24.7 0.0 2.8 2 1 0 2 2 2 2 Cytochrome P450 ABC_membrane PF00664.18 KEY73761.1 - 2.3e-38 132.2 11.8 2.8e-38 131.9 8.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KEY73761.1 - 5.8e-34 117.3 0.0 1.1e-33 116.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KEY73761.1 - 8.7e-07 29.1 0.1 0.0043 17.0 0.0 2.7 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 KEY73761.1 - 2e-05 23.9 0.0 0.0097 15.1 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KEY73761.1 - 4.8e-05 24.1 0.0 0.00015 22.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEY73761.1 - 8.4e-05 22.6 0.2 0.00065 19.7 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 KEY73761.1 - 0.00035 20.4 0.0 0.003 17.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEY73761.1 - 0.001 19.2 0.0 0.0044 17.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KEY73761.1 - 0.001 18.2 0.0 0.0019 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 KEY73761.1 - 0.001 18.5 0.0 0.0068 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 KEY73761.1 - 0.0027 17.2 0.1 0.0071 15.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.9 KEY73761.1 - 0.0033 17.1 0.0 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KEY73761.1 - 0.0068 16.3 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEY73761.1 - 0.011 14.8 0.0 0.049 12.7 0.0 2.1 3 0 0 3 3 3 0 Zeta toxin AAA_18 PF13238.1 KEY73761.1 - 0.014 15.7 0.0 0.044 14.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.1 KEY73761.1 - 0.02 14.7 0.0 0.054 13.3 0.0 1.7 2 0 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.18 KEY73761.1 - 0.021 14.7 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.20 KEY73761.1 - 0.028 13.9 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF1016 PF06250.6 KEY73761.1 - 0.031 13.2 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1016) AAA PF00004.24 KEY73761.1 - 0.033 14.3 0.0 0.17 12.0 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KEY73761.1 - 0.036 13.4 0.0 0.1 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KEY73761.1 - 0.05 13.1 0.0 0.66 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KEY73761.1 - 0.052 13.1 0.2 0.22 11.1 0.0 2.1 3 0 0 3 3 3 0 NACHT domain Miro PF08477.8 KEY73761.1 - 0.052 14.0 0.0 0.14 12.7 0.0 1.7 2 0 0 2 2 1 0 Miro-like protein Rad17 PF03215.10 KEY73761.1 - 0.11 11.1 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 KEY73761.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEY73761.1 - 0.14 12.3 0.0 0.57 10.3 0.0 2.0 2 0 0 2 2 2 0 RNA helicase DUF4470 PF14737.1 KEY73762.1 - 2.1e-26 91.5 0.0 3.5e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 KEY73762.1 - 6.7e-09 35.4 11.2 1.3e-08 34.5 7.7 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 KEY73762.1 - 0.43 10.2 7.9 0.99 9.1 5.5 1.6 1 0 0 1 1 1 0 HIT zinc finger UDPGT PF00201.13 KEY73763.1 - 7.4e-10 37.9 0.0 8.5e-07 27.8 0.0 2.5 3 0 0 3 3 3 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 KEY73763.1 - 0.00019 21.1 0.1 0.00036 20.2 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_trans_1_3 PF13528.1 KEY73763.1 - 0.0061 15.7 0.0 2.9 6.9 0.0 2.6 2 1 1 3 3 3 2 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 KEY73763.1 - 0.019 14.6 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain MFS_1 PF07690.11 KEY73765.1 - 3.6e-38 131.1 35.0 3.6e-38 131.1 24.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY73765.1 - 7.6e-07 28.0 22.2 1.4e-05 23.8 8.8 3.4 3 1 1 4 4 4 2 Sugar (and other) transporter OATP PF03137.15 KEY73765.1 - 0.007 14.4 1.4 0.007 14.4 1.0 1.7 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.1 KEY73765.1 - 6.6 5.0 28.8 0.067 11.5 13.4 2.1 2 0 0 2 2 2 0 MFS/sugar transport protein Fungal_trans PF04082.13 KEY73766.1 - 3.7e-21 75.1 0.0 7.1e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY73766.1 - 0.47 10.3 12.0 0.049 13.5 2.3 2.7 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FMN_dh PF01070.13 KEY73767.1 - 1.1e-119 399.4 0.0 1.4e-119 399.1 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KEY73767.1 - 0.00021 20.3 0.2 0.00039 19.4 0.1 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KEY73767.1 - 0.00023 20.1 0.1 0.00036 19.5 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 KEY73767.1 - 0.0041 16.2 0.0 1.4 7.9 0.0 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 KEY73767.1 - 0.0045 16.1 0.2 0.0083 15.3 0.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 KEY73767.1 - 0.0056 15.9 0.1 0.82 8.8 0.0 2.6 1 1 1 2 2 2 2 Histidine biosynthesis protein IGPS PF00218.16 KEY73767.1 - 0.019 14.0 0.0 0.043 12.8 0.0 1.5 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase PcrB PF01884.12 KEY73767.1 - 0.028 13.6 0.0 0.68 9.1 0.0 2.3 1 1 1 2 2 2 0 PcrB family FAD_binding_4 PF01565.18 KEY73768.1 - 3e-25 88.3 3.7 7.5e-25 87.0 2.6 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY73768.1 - 0.065 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like MSA_2 PF00985.12 KEY73769.1 - 4.1 7.5 10.9 8.5 6.4 7.5 1.4 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Pyr_redox_2 PF07992.9 KEY73770.1 - 1.2e-20 74.3 2.8 4.1e-09 36.6 0.0 3.6 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY73770.1 - 8.8e-11 42.0 1.0 4e-09 36.7 0.7 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY73770.1 - 1.3e-07 31.8 0.0 7.2e-06 26.2 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY73770.1 - 3e-06 26.4 0.4 0.0055 15.6 0.0 3.1 2 1 1 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 KEY73770.1 - 4.4e-06 25.8 5.3 0.0064 15.4 0.2 3.7 3 1 1 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KEY73770.1 - 2.3e-05 23.4 0.0 0.00014 20.9 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 KEY73770.1 - 6.7e-05 21.6 0.5 0.74 8.3 0.1 3.1 2 1 1 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.1 KEY73770.1 - 0.00016 21.5 1.6 1.6 8.4 0.0 3.9 3 1 1 4 4 4 2 FAD-NAD(P)-binding HI0933_like PF03486.9 KEY73770.1 - 0.0014 17.1 0.3 0.05 12.0 0.1 3.2 4 1 1 5 5 5 1 HI0933-like protein DUF4147 PF13660.1 KEY73770.1 - 0.004 16.2 0.2 0.9 8.6 0.2 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4147) NAD_binding_8 PF13450.1 KEY73770.1 - 0.012 15.6 0.1 0.91 9.5 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KEY73770.1 - 0.021 13.9 0.1 0.31 10.0 0.0 2.3 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase TrkA_N PF02254.13 KEY73770.1 - 0.082 12.9 0.1 23 5.0 0.0 3.1 4 0 0 4 4 4 0 TrkA-N domain StbA PF06406.6 KEY73770.1 - 0.15 10.9 0.1 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 StbA protein GIDA PF01134.17 KEY73770.1 - 2.6 6.8 7.3 2.5 6.8 1.1 3.2 3 1 0 4 4 4 0 Glucose inhibited division protein A Acetyltransf_1 PF00583.19 KEY73771.1 - 1.4e-07 31.4 0.0 2.5e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEY73771.1 - 0.00012 22.1 0.0 0.00023 21.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Fringe PF02434.11 KEY73772.1 - 1.7e-05 24.1 0.0 2.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 KEY73772.1 - 0.00041 20.0 0.5 0.00097 18.7 0.4 1.6 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 KEY73772.1 - 0.0054 16.4 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 PAN domain CorA PF01544.13 KEY73773.1 - 5.7e-07 28.8 0.2 2.2e-06 26.9 0.2 2.2 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Zot PF05707.7 KEY73773.1 - 0.0059 16.1 0.1 0.033 13.6 0.0 2.2 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) DUF373 PF04123.8 KEY73773.1 - 0.28 10.1 2.0 0.53 9.2 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) ADH_zinc_N PF00107.21 KEY73774.1 - 6.7e-23 80.6 0.1 1e-22 80.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY73774.1 - 2.2e-08 35.0 0.7 4.4e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Sugar_tr PF00083.19 KEY73775.1 - 2.8e-88 296.4 23.8 3.4e-88 296.1 16.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY73775.1 - 1.6e-25 89.6 37.9 3e-22 78.8 15.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KEY73775.1 - 9.7e-07 27.3 2.6 1.6e-06 26.6 1.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KEY73775.1 - 0.00015 20.3 0.6 0.00015 20.3 0.4 3.4 3 1 1 4 4 4 2 MFS/sugar transport protein DUF791 PF05631.9 KEY73775.1 - 0.00035 19.3 0.4 0.00065 18.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF791) RTA1 PF04479.8 KEY73777.1 - 9.6e-35 120.0 10.6 1.5e-34 119.5 7.4 1.2 1 0 0 1 1 1 1 RTA1 like protein Metallophos_2 PF12850.2 KEY73779.1 - 5.3e-09 36.1 0.0 1e-08 35.2 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KEY73779.1 - 3.3e-06 26.6 2.5 1.1e-05 24.9 1.7 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PNP_UDP_1 PF01048.15 KEY73780.1 - 4.7e-16 58.4 0.1 1.3e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 KEY73780.1 - 1.8e-05 24.4 0.0 4.9e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 NACHT domain DBD_Tnp_Mut PF03108.10 KEY73780.1 - 0.0011 18.4 0.2 0.0024 17.4 0.1 1.4 1 0 0 1 1 1 1 MuDR family transposase DUF3962 PF13111.1 KEY73780.1 - 0.013 14.8 0.2 0.022 14.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3962) AAA_22 PF13401.1 KEY73780.1 - 0.016 15.3 0.0 0.055 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.11 KEY73780.1 - 0.1 11.3 1.9 0.13 11.0 0.3 1.9 2 1 1 3 3 3 0 AFG1-like ATPase NB-ARC PF00931.17 KEY73780.1 - 0.12 11.2 0.1 0.67 8.7 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 KEY73780.1 - 0.13 12.4 0.1 0.41 10.8 0.0 1.9 2 0 0 2 2 2 0 RNA helicase DUF258 PF03193.11 KEY73780.1 - 0.16 11.1 0.0 0.42 9.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 KEY73780.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KEY73780.1 - 0.16 12.2 0.0 0.53 10.5 0.0 1.8 2 0 0 2 2 2 0 ABC transporter adh_short PF00106.20 KEY73781.1 - 4e-09 36.6 0.0 3.4e-08 33.6 0.0 2.0 1 1 1 2 2 2 1 short chain dehydrogenase DUF3140 PF11338.3 KEY73783.1 - 4.6e-32 110.0 1.4 4.6e-32 110.0 1.0 3.8 2 1 2 4 4 4 1 Protein of unknown function (DUF3140) DUF2945 PF11160.3 KEY73783.1 - 0.0027 17.5 0.7 0.0088 15.8 0.5 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) DUF3970 PF13113.1 KEY73783.1 - 0.0067 16.0 0.9 0.016 14.8 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3970) TFIIF_alpha PF05793.7 KEY73783.1 - 4.5 5.5 52.5 5.7 5.1 36.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) dCMP_cyt_deam_1 PF00383.17 KEY73784.1 - 5.3e-10 38.8 0.0 6.7e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF2946 PF11162.3 KEY73784.1 - 0.032 14.4 0.6 0.043 14.0 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) zf-LITAF-like PF10601.4 KEY73785.1 - 2.3e-07 30.5 8.7 3.4e-07 30.0 6.1 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-H2C2_2 PF13465.1 KEY73785.1 - 0.082 13.2 0.8 0.8 10.1 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-CHY PF05495.7 KEY73785.1 - 3.2 7.9 8.4 1.1 9.4 3.2 2.0 1 1 1 2 2 2 0 CHY zinc finger Ank_2 PF12796.2 KEY73786.1 - 6.2e-43 145.0 16.3 7.3e-15 55.0 0.5 2.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KEY73786.1 - 2.5e-22 77.4 12.0 1.1e-08 34.4 0.2 4.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KEY73786.1 - 4.3e-18 64.9 10.6 5.9e-07 29.5 0.2 4.4 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEY73786.1 - 1.2e-17 63.9 6.4 4.4e-07 30.2 0.2 4.0 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY73786.1 - 1.4e-16 58.8 4.3 0.00014 21.7 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Sugar_tr PF00083.19 KEY73789.1 - 1e-84 284.7 25.8 1.4e-84 284.3 17.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY73789.1 - 2.4e-11 42.9 43.7 3.5e-08 32.5 10.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.22 KEY73790.1 - 5.2e-52 175.7 0.0 3.5e-25 88.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 KEY73790.1 - 5.9e-49 166.0 34.4 1.7e-30 105.7 4.6 3.1 3 0 0 3 3 3 2 ABC-2 type transporter AAA_21 PF13304.1 KEY73790.1 - 2.2e-21 77.0 0.4 5.3e-09 36.4 0.2 4.2 3 1 0 3 3 3 3 AAA domain AAA_16 PF13191.1 KEY73790.1 - 4e-09 36.7 0.1 0.002 18.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 KEY73790.1 - 4.9e-09 35.7 0.1 0.001 18.3 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KEY73790.1 - 6.2e-09 35.4 0.0 0.069 12.1 0.0 4.1 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 KEY73790.1 - 7.4e-09 35.8 0.3 0.023 14.8 0.1 3.8 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 KEY73790.1 - 1.8e-08 33.9 0.2 0.002 17.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 KEY73790.1 - 2.9e-08 33.0 0.1 0.0061 15.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KEY73790.1 - 5.2e-08 33.4 7.6 0.0034 17.7 1.2 2.9 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 KEY73790.1 - 5.8e-08 32.5 0.0 0.0044 16.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_29 PF13555.1 KEY73790.1 - 2.2e-07 30.3 1.0 0.0083 15.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KEY73790.1 - 1.9e-06 28.6 0.0 0.017 15.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KEY73790.1 - 5.5e-06 26.0 0.3 0.0031 17.2 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_10 PF12846.2 KEY73790.1 - 9.7e-06 25.2 2.5 0.025 14.0 0.1 2.6 3 0 0 3 3 2 2 AAA-like domain AAA_28 PF13521.1 KEY73790.1 - 1.6e-05 24.9 2.0 0.031 14.2 0.0 3.2 4 0 0 4 4 2 2 AAA domain Arch_ATPase PF01637.13 KEY73790.1 - 2.3e-05 24.2 0.0 0.099 12.3 0.0 2.4 2 0 0 2 2 2 2 Archaeal ATPase SbcCD_C PF13558.1 KEY73790.1 - 2.4e-05 24.1 0.9 0.24 11.3 0.0 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 KEY73790.1 - 3e-05 23.6 0.1 0.05 13.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain cobW PF02492.14 KEY73790.1 - 3.2e-05 23.4 2.1 0.081 12.3 0.2 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 KEY73790.1 - 3.9e-05 23.2 0.3 0.034 13.6 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_33 PF13671.1 KEY73790.1 - 8.8e-05 22.4 0.0 0.16 11.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KEY73790.1 - 0.0001 21.3 0.3 0.071 11.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein RNA_helicase PF00910.17 KEY73790.1 - 0.00016 21.8 0.1 0.96 9.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 KEY73790.1 - 0.00022 21.5 0.0 0.34 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KEY73790.1 - 0.00023 20.9 0.2 1.5 8.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) MobB PF03205.9 KEY73790.1 - 0.0003 20.5 0.3 0.47 10.1 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 KEY73790.1 - 0.00035 21.0 0.1 0.74 10.3 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein NTPase_1 PF03266.10 KEY73790.1 - 0.00037 20.2 0.4 0.15 11.7 0.1 3.6 4 0 0 4 4 4 1 NTPase ATP_bind_1 PF03029.12 KEY73790.1 - 0.00058 19.4 0.1 0.2 11.1 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 KEY73790.1 - 0.00088 18.4 0.1 0.34 9.9 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.1 KEY73790.1 - 0.0025 17.4 0.7 1 8.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain Pox_A32 PF04665.7 KEY73790.1 - 0.0042 16.4 0.4 0.6 9.3 0.0 2.5 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_14 PF13173.1 KEY73790.1 - 0.0051 16.7 0.0 2.4 8.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KEY73790.1 - 0.0065 16.4 2.6 0.93 9.4 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.24 KEY73790.1 - 0.009 16.2 0.2 4.8 7.3 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF4388 PF14332.1 KEY73790.1 - 0.011 15.5 0.0 0.066 13.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4388) DUF2075 PF09848.4 KEY73790.1 - 0.012 14.6 0.1 0.5 9.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 KEY73790.1 - 0.014 15.0 0.1 7.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Septin PF00735.13 KEY73790.1 - 0.014 14.4 0.2 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Septin PRK PF00485.13 KEY73790.1 - 0.016 14.7 0.2 1 8.8 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ABC_ATPase PF09818.4 KEY73790.1 - 0.027 13.0 0.2 0.14 10.6 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class SRP54 PF00448.17 KEY73790.1 - 0.055 12.9 0.8 6.9 6.0 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP-synt_ab PF00006.20 KEY73790.1 - 0.063 12.7 0.0 3 7.2 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 KEY73790.1 - 0.086 12.3 0.3 15 5.0 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PDR_CDR PF06422.7 KEY73790.1 - 0.098 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 CDR ABC transporter NB-ARC PF00931.17 KEY73790.1 - 0.1 11.4 0.0 3.3 6.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain SRPRB PF09439.5 KEY73790.1 - 0.11 11.6 0.3 8.7 5.5 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit KAP_NTPase PF07693.9 KEY73790.1 - 0.13 11.2 0.0 14 4.5 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain Dynamin_N PF00350.18 KEY73790.1 - 0.16 11.7 6.9 4.6 7.0 0.2 3.7 4 0 0 4 4 3 0 Dynamin family IstB_IS21 PF01695.12 KEY73790.1 - 0.24 10.7 2.2 8.6 5.7 0.0 3.3 4 0 0 4 4 3 0 IstB-like ATP binding protein DUF87 PF01935.12 KEY73790.1 - 4.1 7.1 8.6 1.6 8.5 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 Amidohydro_4 PF13147.1 KEY73791.1 - 1.1e-17 64.9 0.0 2.1e-16 60.7 0.0 2.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KEY73791.1 - 4e-17 62.8 0.6 6.1e-10 39.2 0.1 3.0 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KEY73791.1 - 1.4e-09 37.5 0.0 3.1e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KEY73791.1 - 4.7e-07 29.3 0.1 0.0005 19.4 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family polyprenyl_synt PF00348.12 KEY73792.1 - 1.4e-53 181.4 0.0 1.8e-50 171.2 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 KEY73792.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Vma12 PF11712.3 KEY73793.1 - 1.9e-35 121.6 0.0 2.9e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase UPF0220 PF05255.6 KEY73793.1 - 0.01 15.1 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) zf-C2H2_3 PF13878.1 KEY73794.1 - 0.027 14.0 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO Lipocalin_5 PF13924.1 KEY73795.1 - 1.1e-24 86.7 0.1 1.2e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain NACHT PF05729.7 KEY73796.1 - 2.6e-10 40.1 0.1 7.4e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEY73796.1 - 1.4e-05 25.1 0.1 5.1e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEY73796.1 - 7.4e-05 22.8 0.0 0.00033 20.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KEY73796.1 - 0.025 14.8 0.1 0.1 12.8 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.1 KEY73796.1 - 0.035 13.6 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEY73796.1 - 0.05 13.9 0.1 0.35 11.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 KEY73796.1 - 0.062 12.4 0.0 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 KEY73796.1 - 0.08 13.7 0.0 0.48 11.2 0.0 2.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KEY73796.1 - 0.089 12.4 1.1 1.2 8.7 0.0 2.9 3 0 0 3 3 3 0 Archaeal ATPase AAA_29 PF13555.1 KEY73796.1 - 0.12 11.9 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DLH PF01738.13 KEY73797.1 - 3.5e-16 59.1 0.0 4.9e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KEY73797.1 - 6.9e-07 29.1 0.0 9.4e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY73797.1 - 0.00016 21.6 1.6 0.0011 18.8 0.5 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family EBP PF05241.7 KEY73798.1 - 4.7e-61 205.1 8.9 5.8e-61 204.9 6.2 1.0 1 0 0 1 1 1 1 Emopamil binding protein Cellulase PF00150.13 KEY73803.1 - 1.6e-49 168.5 0.7 2.2e-49 168.1 0.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KEY73803.1 - 2.3e-13 49.5 7.5 2.3e-13 49.5 5.2 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain Kei1 PF08552.6 KEY73803.1 - 0.12 11.9 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 AlaDh_PNT_N PF05222.10 KEY73804.1 - 7.1e-20 71.3 0.0 1.2e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KEY73804.1 - 8.2e-12 45.0 0.0 1.5e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.11 KEY73805.1 - 1.1e-30 106.5 29.4 1.1e-30 106.5 20.4 1.7 1 1 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_18 PF00704.23 KEY73806.1 - 1.8e-99 333.4 0.5 2.1e-99 333.2 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AP_endonuc_2 PF01261.19 KEY73806.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Nop PF01798.13 KEY73807.1 - 5.3e-53 178.3 0.4 9.4e-53 177.5 0.3 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOP5NT PF08156.8 KEY73807.1 - 5.9e-17 61.5 0.0 5.9e-17 61.5 0.0 2.2 2 0 0 2 2 2 1 NOP5NT (NUC127) domain NOSIC PF08060.8 KEY73807.1 - 1.5e-07 31.1 0.0 3.1e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain RNA_polI_A34 PF08208.6 KEY73807.1 - 0.0014 18.3 15.4 0.0027 17.4 10.7 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.9 KEY73807.1 - 5.5 4.9 11.8 8.4 4.2 8.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Fungal_trans_2 PF11951.3 KEY73808.1 - 2.4e-05 23.0 0.1 0.00017 20.2 0.1 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF1929 PF09118.6 KEY73809.1 - 9.2e-23 80.1 0.0 1.8e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.1 KEY73809.1 - 1.2e-14 53.7 9.6 9.7e-05 22.3 0.0 5.5 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.20 KEY73809.1 - 3.1e-14 52.2 1.1 0.00028 20.3 0.0 4.0 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.1 KEY73809.1 - 3.6e-12 45.8 7.8 0.0003 20.5 0.0 4.8 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KEY73809.1 - 5.9e-11 41.6 2.6 0.024 14.3 0.1 5.3 4 1 0 4 4 4 4 Kelch motif Glyoxal_oxid_N PF07250.6 KEY73809.1 - 0.00026 20.1 0.1 1.3 8.0 0.0 3.2 2 2 1 3 3 3 2 Glyoxal oxidase N-terminus Kelch_3 PF13415.1 KEY73809.1 - 0.00034 20.6 16.0 0.0014 18.7 0.0 5.2 6 0 0 6 6 6 2 Galactose oxidase, central domain PAN_1 PF00024.21 KEY73809.1 - 0.0043 16.7 0.1 0.0076 15.9 0.1 1.3 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 KEY73809.1 - 0.084 12.7 1.4 0.19 11.5 1.0 1.6 1 0 0 1 1 1 0 PAN-like domain ubiquitin PF00240.18 KEY73810.1 - 1.4e-34 117.2 0.9 2.7e-34 116.3 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 KEY73810.1 - 1.6e-28 98.2 2.3 3.2e-28 97.2 1.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 KEY73810.1 - 5.2e-20 70.9 0.7 1e-19 69.9 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KEY73810.1 - 7.8e-06 26.0 0.6 3.9e-05 23.8 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KEY73810.1 - 0.00012 21.8 0.1 0.00019 21.1 0.0 1.3 1 1 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KEY73810.1 - 0.0007 19.4 0.8 0.0015 18.4 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KEY73810.1 - 0.0045 17.1 0.6 0.0061 16.7 0.4 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 KEY73810.1 - 0.059 13.4 1.0 0.089 12.8 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 KEY73810.1 - 0.076 11.3 2.9 1.5 7.0 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Ribosomal_S26e PF01283.14 KEY73811.1 - 2.1e-50 169.7 9.0 2.6e-50 169.4 6.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 KEY73811.1 - 0.053 13.8 1.1 1.3 9.4 0.4 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain DUF1918 PF08940.6 KEY73811.1 - 0.081 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Zn_ribbon_2 PF12674.2 KEY73811.1 - 0.11 12.8 0.4 9 6.7 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain GFA PF04828.9 KEY73812.1 - 2.7e-19 68.8 0.5 1.2e-09 38.0 0.0 3.3 2 1 1 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme ADH_zinc_N PF00107.21 KEY73812.1 - 6.2e-11 41.9 0.0 1.2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY73812.1 - 1.5e-07 31.1 0.1 5e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KEY73812.1 - 0.077 13.8 0.0 0.2 12.5 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase LVIVD PF08309.6 KEY73813.1 - 0.0025 16.7 0.2 1.6 7.7 0.0 3.3 3 0 0 3 3 3 2 LVIVD repeat TBD PF12845.2 KEY73814.1 - 0.037 13.5 1.2 0.082 12.4 0.8 1.5 1 0 0 1 1 1 0 TBD domain YceG PF02618.11 KEY73814.1 - 0.066 12.2 0.0 0.098 11.6 0.0 1.2 1 0 0 1 1 1 0 YceG-like family p450 PF00067.17 KEY73815.1 - 4.6e-25 88.0 0.0 5.5e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_cc PF11790.3 KEY73816.1 - 1.3e-53 181.8 0.0 1.5e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core AMP-binding PF00501.23 KEY73817.1 - 0 1915.2 0.0 8.1e-88 294.5 0.0 7.2 7 0 0 7 7 7 7 AMP-binding enzyme Condensation PF00668.15 KEY73817.1 - 2e-261 864.1 0.1 2.1e-43 148.3 0.0 8.4 7 1 1 8 8 8 7 Condensation domain PP-binding PF00550.20 KEY73817.1 - 3.3e-89 293.1 9.8 1.3e-11 44.5 0.0 9.1 8 0 0 8 8 8 8 Phosphopantetheine attachment site NAD_binding_4 PF07993.7 KEY73817.1 - 4.5e-41 140.4 0.0 7.9e-41 139.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding_C PF13193.1 KEY73817.1 - 4.6e-24 85.1 0.9 0.0008 20.3 0.0 9.3 9 0 0 9 9 9 4 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 KEY73817.1 - 9.8e-11 41.5 0.0 2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family MAP65_ASE1 PF03999.7 KEY73817.1 - 3.6 6.0 0.1 7.3 5.0 0.1 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) adh_short PF00106.20 KEY73818.1 - 5e-17 62.3 0.4 7.5e-17 61.7 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY73818.1 - 7.6e-10 38.7 0.2 1.1e-09 38.1 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY73818.1 - 0.0017 18.1 0.0 0.0027 17.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEY73818.1 - 0.003 17.0 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY73818.1 - 0.022 14.7 0.6 0.063 13.2 0.4 2.0 1 1 0 1 1 1 0 NADH(P)-binding rve_2 PF13333.1 KEY73819.1 - 0.053 13.5 0.2 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain SMC_N PF02463.14 KEY73821.1 - 1.3e-75 253.4 14.8 1e-74 250.4 10.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KEY73821.1 - 5.5e-27 94.1 0.0 2.3e-26 92.1 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KEY73821.1 - 5.7e-14 52.7 1.7 1.9e-05 24.7 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KEY73821.1 - 8.3e-05 22.0 0.0 0.00017 21.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tropomyosin_1 PF12718.2 KEY73821.1 - 8.4e-05 22.4 13.5 8.4e-05 22.4 9.4 7.7 3 2 4 8 8 8 4 Tropomyosin like IncA PF04156.9 KEY73821.1 - 0.0038 16.8 10.0 0.0038 16.8 6.9 7.7 3 2 4 7 7 7 4 IncA protein TPR_MLP1_2 PF07926.7 KEY73821.1 - 0.52 10.0 114.2 0.12 12.1 13.0 8.2 2 2 5 8 8 8 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 KEY73821.1 - 0.79 8.8 31.3 0.048 12.8 1.5 5.1 3 2 1 5 5 5 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 KEY73821.1 - 4.7 5.5 105.2 0.21 10.0 8.1 5.4 4 2 2 6 6 6 0 AAA domain ELYS PF13934.1 KEY73822.1 - 8.9e-57 192.4 1.8 1e-56 192.1 1.3 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly p450 PF00067.17 KEY73823.1 - 7.6e-37 126.9 0.0 3.6e-24 85.1 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 Mpv17_PMP22 PF04117.7 KEY73824.1 - 2.1e-20 72.0 2.2 2.1e-20 72.0 1.5 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family Phage_GP20 PF06810.6 KEY73825.1 - 0.00037 19.9 7.5 0.00037 19.9 5.2 4.7 4 1 1 5 5 5 1 Phage minor structural protein GP20 zf-C4H2 PF10146.4 KEY73825.1 - 0.0056 16.7 8.1 0.28 11.1 0.8 3.0 2 1 1 3 3 3 2 Zinc finger-containing protein Reo_sigmaC PF04582.7 KEY73825.1 - 0.015 14.4 12.8 0.54 9.3 0.0 4.1 2 1 1 4 4 4 0 Reovirus sigma C capsid protein CagE_TrbE_VirB PF03135.9 KEY73825.1 - 0.13 11.9 1.7 0.35 10.5 1.2 1.7 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system Relaxase PF03432.9 KEY73825.1 - 0.24 10.7 3.8 0.81 9.0 2.7 1.9 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain G-gamma PF00631.17 KEY73825.1 - 2.7 7.8 8.9 28 4.5 0.2 4.3 4 0 0 4 4 4 0 GGL domain ADIP PF11559.3 KEY73825.1 - 2.7 7.8 35.8 0.11 12.4 6.9 5.0 4 1 2 6 6 6 0 Afadin- and alpha -actinin-Binding MSP1_C PF07462.6 KEY73827.1 - 4.6 5.4 4.6 6.6 4.9 3.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus NTP_transf_2 PF01909.18 KEY73828.1 - 3.1e-08 33.8 0.0 1.3e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain Phage_cap_E PF03864.10 KEY73828.1 - 0.092 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Phage major capsid protein E DUF294 PF03445.8 KEY73828.1 - 0.12 11.9 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 Peptidase_S49 PF01343.13 KEY73828.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 1 0 1 1 1 0 Peptidase family S49 Fungal_trans PF04082.13 KEY73830.1 - 1.8e-05 23.7 0.0 2.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cellulase PF00150.13 KEY73831.1 - 1e-37 129.9 2.4 1.6e-37 129.2 1.6 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.9 KEY73831.1 - 2.9e-21 75.0 0.9 1.3e-19 69.7 0.2 3.2 3 0 0 3 3 3 1 Carbohydrate binding domain X2 DUF1479 PF07350.7 KEY73832.1 - 6.8e-154 512.3 0.0 8e-154 512.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 KEY73832.1 - 0.00066 19.7 0.2 0.22 11.5 0.1 2.5 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Microtub_assoc PF07989.6 KEY73833.1 - 6.2e-20 70.8 8.0 6.2e-20 70.8 5.5 8.1 6 2 3 10 10 10 1 Microtubule associated Mto2_bdg PF12808.2 KEY73833.1 - 1.1e-09 38.2 13.9 1.1e-09 38.2 9.6 13.2 14 3 2 16 16 16 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Reo_sigmaC PF04582.7 KEY73833.1 - 0.00077 18.7 40.9 0.016 14.3 1.6 6.4 4 1 1 6 6 6 4 Reovirus sigma C capsid protein NPV_P10 PF05531.7 KEY73833.1 - 0.017 15.3 19.7 0.033 14.4 0.0 6.7 6 2 0 6 6 6 0 Nucleopolyhedrovirus P10 protein Vip3A_N PF12495.3 KEY73833.1 - 0.023 14.4 3.1 8.6 6.0 0.2 3.6 3 0 0 3 3 3 0 Vegetative insecticide protein 3A N terminal Fib_alpha PF08702.5 KEY73833.1 - 4.3 7.4 70.7 0.19 11.8 3.6 7.8 5 2 3 8 8 8 0 Fibrinogen alpha/beta chain family MARVEL PF01284.18 KEY73835.1 - 1.4e-06 28.1 13.2 2.9e-06 27.1 8.7 1.8 1 1 1 2 2 2 2 Membrane-associating domain Virul_fac_BrkB PF03631.10 KEY73835.1 - 1.4 8.2 23.0 0.3 10.3 10.9 2.1 2 0 0 2 2 2 0 Virulence factor BrkB 7TMR-DISM_7TM PF07695.6 KEY73835.1 - 1.5 8.4 26.7 3.7 7.1 1.5 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling Oxidored_q2 PF00420.19 KEY73835.1 - 3.8 7.1 13.1 0.84 9.2 4.2 2.4 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Arginase PF00491.16 KEY73836.1 - 3.7e-73 246.2 0.3 4.6e-73 245.9 0.2 1.0 1 0 0 1 1 1 1 Arginase family Glyco_transf_90 PF05686.7 KEY73837.1 - 2.9e-14 52.5 2.5 2.9e-11 42.6 0.0 3.0 3 0 0 3 3 3 2 Glycosyl transferase family 90 AAA PF00004.24 KEY73839.1 - 1.4e-41 141.8 0.0 3.8e-41 140.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KEY73839.1 - 2.2e-23 81.8 0.0 2.4e-22 78.5 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 KEY73839.1 - 7.2e-18 64.2 3.6 7.2e-18 64.2 2.5 2.4 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.7 KEY73839.1 - 2.8e-06 26.5 0.0 3.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KEY73839.1 - 3.8e-06 27.7 0.2 1.8e-05 25.5 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.1 KEY73839.1 - 1.8e-05 24.8 0.1 0.0073 16.4 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 KEY73839.1 - 2.5e-05 24.1 0.0 6.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KEY73839.1 - 2.5e-05 23.7 0.0 6.2e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 KEY73839.1 - 4.1e-05 23.6 0.0 0.0081 16.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.9 KEY73839.1 - 4.2e-05 23.2 0.0 0.00016 21.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KEY73839.1 - 5e-05 22.1 0.0 0.00011 21.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 KEY73839.1 - 8.3e-05 22.6 0.0 0.0025 17.8 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 KEY73839.1 - 0.00016 20.7 0.0 0.00095 18.1 0.0 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF815) PrkA PF06798.7 KEY73839.1 - 0.00068 18.9 0.1 0.0014 17.9 0.0 1.6 1 0 0 1 1 1 1 PrkA serine protein kinase C-terminal domain AAA_33 PF13671.1 KEY73839.1 - 0.00084 19.2 0.0 0.002 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEY73839.1 - 0.00089 18.7 0.1 0.19 11.1 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 KEY73839.1 - 0.0019 18.1 0.0 0.0043 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.1 KEY73839.1 - 0.0043 16.6 0.4 0.024 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEY73839.1 - 0.011 16.0 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KEY73839.1 - 0.014 14.5 0.0 0.11 11.6 0.0 2.1 1 1 1 2 2 2 0 Zeta toxin AAA_19 PF13245.1 KEY73839.1 - 0.02 14.6 0.0 0.065 13.0 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 KEY73839.1 - 0.022 13.9 0.0 0.065 12.3 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_21 PF13304.1 KEY73839.1 - 0.028 14.4 0.2 2.5 7.9 0.0 2.3 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 KEY73839.1 - 0.03 13.9 0.0 0.62 9.7 0.0 2.3 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.11 KEY73839.1 - 0.038 13.2 0.0 0.097 11.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Arch_ATPase PF01637.13 KEY73839.1 - 0.043 13.5 0.3 0.4 10.3 0.0 2.4 2 1 1 3 3 3 0 Archaeal ATPase Parvo_NS1 PF01057.12 KEY73839.1 - 0.08 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Torsin PF06309.6 KEY73839.1 - 0.093 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Torsin Sigma54_activ_2 PF14532.1 KEY73839.1 - 0.12 12.4 0.1 0.54 10.3 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain Prefoldin_2 PF01920.15 KEY73840.1 - 4e-18 65.1 12.4 5.1e-18 64.7 8.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit IncA PF04156.9 KEY73840.1 - 0.00027 20.6 14.0 0.0013 18.3 9.7 1.8 1 1 0 1 1 1 1 IncA protein DUF3584 PF12128.3 KEY73840.1 - 0.00066 17.1 5.3 0.00073 17.0 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Spc24 PF08286.6 KEY73840.1 - 0.0028 17.3 4.6 1.1 8.9 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Sas10_Utp3 PF04000.10 KEY73840.1 - 0.0066 16.6 3.2 0.076 13.2 0.7 2.2 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Spc7 PF08317.6 KEY73840.1 - 0.013 14.1 9.0 0.016 13.9 6.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Fez1 PF06818.10 KEY73840.1 - 0.045 13.7 8.7 0.049 13.6 0.6 2.2 2 0 0 2 2 2 0 Fez1 WEMBL PF05701.6 KEY73840.1 - 0.046 12.1 9.7 0.08 11.3 6.7 1.3 1 1 0 1 1 1 0 Weak chloroplast movement under blue light HrpB7 PF09486.5 KEY73840.1 - 0.05 13.5 5.8 0.16 11.8 4.0 1.7 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) TMF_DNA_bd PF12329.3 KEY73840.1 - 0.056 13.2 13.3 0.13 12.0 0.8 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Cep57_MT_bd PF06657.8 KEY73840.1 - 0.062 13.2 7.8 0.72 9.8 0.8 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Prefoldin PF02996.12 KEY73840.1 - 0.066 12.8 10.5 0.13 11.9 0.9 2.4 1 1 1 2 2 2 0 Prefoldin subunit DUF2968 PF11180.3 KEY73840.1 - 0.068 12.5 12.8 0.23 10.8 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) TPR_MLP1_2 PF07926.7 KEY73840.1 - 0.078 12.7 12.7 0.51 10.0 4.7 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4201 PF13870.1 KEY73840.1 - 0.082 12.3 7.8 0.17 11.3 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) GreA_GreB_N PF03449.10 KEY73840.1 - 0.087 12.8 3.6 7.9 6.6 0.0 2.6 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal COG5 PF10392.4 KEY73840.1 - 0.095 12.6 2.3 4 7.3 0.1 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF342 PF03961.8 KEY73840.1 - 0.1 11.0 6.0 0.14 10.5 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) RmuC PF02646.11 KEY73840.1 - 0.1 11.4 6.0 0.43 9.3 0.9 2.0 2 0 0 2 2 2 0 RmuC family SlyX PF04102.7 KEY73840.1 - 0.11 12.8 6.8 1.9 8.8 0.0 2.4 2 0 0 2 2 2 0 SlyX Occludin_ELL PF07303.8 KEY73840.1 - 0.13 12.9 6.1 0.16 12.7 0.9 2.1 2 0 0 2 2 2 0 Occludin homology domain KH_5 PF13184.1 KEY73840.1 - 0.15 11.8 0.9 0.3 10.9 0.1 1.8 2 0 0 2 2 2 0 NusA-like KH domain Prefoldin_3 PF13758.1 KEY73840.1 - 0.16 11.7 3.6 0.29 10.9 2.5 1.4 1 1 0 1 1 1 0 Prefoldin subunit DUF848 PF05852.6 KEY73840.1 - 0.16 11.7 8.3 2 8.2 0.3 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DivIVA PF05103.8 KEY73840.1 - 0.18 11.8 7.3 5.3 7.1 0.1 2.2 2 0 0 2 2 2 0 DivIVA protein Ribosomal_L29 PF00831.18 KEY73840.1 - 0.2 11.3 4.4 8.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Ribosomal L29 protein ERM PF00769.14 KEY73840.1 - 0.2 11.1 8.0 0.26 10.8 5.5 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF904 PF06005.7 KEY73840.1 - 0.22 11.8 10.0 1.7 8.9 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Viral_P18 PF04521.8 KEY73840.1 - 0.24 10.8 3.3 7 6.1 1.4 2.2 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein NPV_P10 PF05531.7 KEY73840.1 - 0.25 11.6 5.6 3.7 7.8 0.2 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein COG6 PF06419.6 KEY73840.1 - 0.26 9.3 6.8 0.34 8.9 1.3 2.0 1 1 1 2 2 2 0 Conserved oligomeric complex COG6 CENP-H PF05837.7 KEY73840.1 - 0.29 11.3 6.5 2.1 8.5 0.2 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Baculo_PEP_C PF04513.7 KEY73840.1 - 0.31 10.8 3.2 4.2 7.1 0.2 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4279 PF14106.1 KEY73840.1 - 0.37 10.6 0.1 0.37 10.6 0.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4279) IFT57 PF10498.4 KEY73840.1 - 0.41 9.3 8.7 0.58 8.8 0.2 2.0 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 DUF4200 PF13863.1 KEY73840.1 - 0.42 10.5 12.8 1.8 8.5 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Tropomyosin_1 PF12718.2 KEY73840.1 - 0.45 10.3 12.0 2.1 8.1 3.6 2.2 2 0 0 2 2 2 0 Tropomyosin like FlxA PF14282.1 KEY73840.1 - 0.47 10.4 10.6 2.1 8.3 0.4 2.2 2 0 0 2 2 2 0 FlxA-like protein FliD_C PF07195.7 KEY73840.1 - 0.47 9.6 3.9 2.5 7.3 2.7 1.8 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus FlaC_arch PF05377.6 KEY73840.1 - 0.56 10.1 3.8 4.3 7.3 0.2 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.1 KEY73840.1 - 0.59 10.6 8.3 6.5 7.2 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) AATF-Che1 PF13339.1 KEY73840.1 - 0.62 10.2 6.3 7.2 6.7 0.1 2.1 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DASH_Dad3 PF08656.5 KEY73840.1 - 0.63 9.7 4.7 2.8 7.7 0.9 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 TSC22 PF01166.13 KEY73840.1 - 0.63 10.0 0.1 0.63 10.0 0.1 2.5 2 1 0 2 2 2 0 TSC-22/dip/bun family DUF4559 PF15112.1 KEY73840.1 - 0.65 9.0 5.0 0.8 8.8 3.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) End3 PF12761.2 KEY73840.1 - 0.72 9.4 8.7 1 8.9 6.0 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Bacillus_HBL PF05791.6 KEY73840.1 - 0.73 9.1 4.7 1.1 8.6 3.2 1.4 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) ADIP PF11559.3 KEY73840.1 - 0.75 9.6 11.3 0.58 10.0 0.3 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Mnd1 PF03962.10 KEY73840.1 - 0.8 9.3 10.6 8.6 5.9 7.4 1.9 1 1 0 1 1 1 0 Mnd1 family Laminin_II PF06009.7 KEY73840.1 - 0.8 9.4 5.2 2.1 8.1 1.9 2.0 1 1 1 2 2 2 0 Laminin Domain II zf-CpG_bind_C PF12269.3 KEY73840.1 - 0.84 9.0 4.3 0.44 9.9 0.8 1.8 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain Atg14 PF10186.4 KEY73840.1 - 0.85 8.5 10.2 2 7.2 7.1 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HR1 PF02185.11 KEY73840.1 - 0.87 9.3 7.6 1.1 8.9 0.3 2.5 2 1 0 2 2 2 0 Hr1 repeat Lzipper-MIP1 PF14389.1 KEY73840.1 - 0.87 9.7 8.3 3.6 7.7 0.1 2.4 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF1640 PF07798.6 KEY73840.1 - 0.95 9.4 8.2 6.8 6.6 5.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) YgaB PF14182.1 KEY73840.1 - 1.3 9.3 10.6 0.2 11.9 1.2 2.3 2 1 0 2 2 2 0 YgaB-like protein Fib_alpha PF08702.5 KEY73840.1 - 1.3 9.0 7.9 17 5.5 5.5 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Cast PF10174.4 KEY73840.1 - 1.5 6.7 12.2 27 2.6 8.3 1.9 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF1664 PF07889.7 KEY73840.1 - 1.5 8.5 5.1 11 5.7 3.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2802 PF10975.3 KEY73840.1 - 1.6 8.5 7.9 6.1 6.6 2.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) Rootletin PF15035.1 KEY73840.1 - 1.6 8.6 8.7 1.2 9.0 2.3 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DivIC PF04977.10 KEY73840.1 - 1.6 8.2 14.3 0.59 9.6 0.5 2.9 2 1 0 2 2 2 0 Septum formation initiator DUF3138 PF11336.3 KEY73840.1 - 1.8 6.6 3.8 3.7 5.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) COG2 PF06148.6 KEY73840.1 - 1.9 8.3 6.7 6.5 6.6 1.9 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Macoilin PF09726.4 KEY73840.1 - 1.9 6.6 7.7 2.7 6.1 5.3 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF964 PF06133.6 KEY73840.1 - 1.9 8.5 11.4 0.26 11.3 3.5 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF964) Seryl_tRNA_N PF02403.17 KEY73840.1 - 2.2 8.3 9.1 5.1 7.1 0.6 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4164 PF13747.1 KEY73840.1 - 2.4 8.3 9.2 5.5 7.2 2.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Snapin_Pallidin PF14712.1 KEY73840.1 - 2.6 8.4 6.8 20 5.5 4.1 2.2 1 1 1 2 2 2 0 Snapin/Pallidin AAA_13 PF13166.1 KEY73840.1 - 2.9 6.2 8.5 4.8 5.5 5.9 1.3 1 1 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.4 KEY73840.1 - 3 7.6 13.7 49 3.7 9.5 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ax_dynein_light PF10211.4 KEY73840.1 - 3.6 7.3 12.2 3.4 7.4 3.8 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain GvpK PF05121.7 KEY73840.1 - 4 7.3 6.8 17 5.3 0.3 2.1 2 0 0 2 2 2 0 Gas vesicle protein K Kinetocho_Slk19 PF12709.2 KEY73840.1 - 5.2 7.2 9.2 7.4 6.7 0.3 2.3 2 0 0 2 2 2 0 Central kinetochore-associated bZIP_2 PF07716.10 KEY73840.1 - 5.2 6.9 12.0 9.9 6.0 1.8 3.6 2 2 2 4 4 4 0 Basic region leucine zipper Nup54 PF13874.1 KEY73840.1 - 5.5 6.6 7.6 2.3 7.9 1.4 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 TBPIP PF07106.8 KEY73840.1 - 5.8 6.4 10.9 8.5 5.8 0.9 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 KEY73840.1 - 6.8 4.4 6.7 9.8 3.8 4.6 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 KEY73840.1 - 6.9 7.0 9.3 14 6.0 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Syntaxin PF00804.20 KEY73840.1 - 7 6.8 10.1 15 5.7 2.4 2.1 1 1 1 2 2 2 0 Syntaxin DUF812 PF05667.6 KEY73840.1 - 8.1 4.8 11.0 4.7 5.5 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Med21 PF11221.3 KEY73840.1 - 9.6 6.1 9.5 2.7 7.9 3.1 2.1 2 0 0 2 2 2 0 Subunit 21 of Mediator complex JAB PF01398.16 KEY73841.1 - 3e-13 49.5 0.0 6.9e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 KEY73841.1 - 6.9e-09 35.6 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 KEY73841.1 - 2.4e-05 23.8 0.0 5.8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Glyco_hydro_61 PF03443.9 KEY73842.1 - 6.4e-62 209.2 0.0 7.8e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DDE_1 PF03184.14 KEY73843.1 - 1.3e-50 171.5 0.0 1.4e-49 168.1 0.0 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KEY73843.1 - 0.00011 21.9 0.0 0.00026 20.7 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DivIC PF04977.10 KEY73843.1 - 0.017 14.6 0.1 0.092 12.2 0.0 2.2 3 0 0 3 3 3 0 Septum formation initiator NB-ARC PF00931.17 KEY73844.1 - 2.5e-13 49.5 0.0 4.1e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KEY73844.1 - 3.4e-08 33.6 0.0 1e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain TPR_12 PF13424.1 KEY73844.1 - 5.6e-06 26.2 5.7 1.8e-05 24.6 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 KEY73844.1 - 7.9e-05 22.4 1.1 1.7 8.6 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat DUF676 PF05057.9 KEY73844.1 - 0.00024 20.4 0.0 0.00047 19.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_7 PF13176.1 KEY73844.1 - 0.00054 19.5 3.1 2.4 8.1 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEY73844.1 - 0.0056 17.3 0.5 3.4 8.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 KEY73844.1 - 0.014 15.3 0.0 0.035 13.9 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family NACHT PF05729.7 KEY73844.1 - 0.022 14.4 0.0 0.048 13.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain TPR_2 PF07719.12 KEY73844.1 - 0.024 14.5 0.5 49 4.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 KEY73844.1 - 0.049 13.7 1.8 2.5 8.2 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF3112 PF11309.3 KEY73845.1 - 0.014 15.1 2.9 0.026 14.3 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) SUR7 PF06687.7 KEY73845.1 - 7.8 6.0 14.2 11 5.5 9.8 1.3 1 0 0 1 1 1 0 SUR7/PalI family Abhydrolase_1 PF00561.15 KEY73846.1 - 2.5e-12 46.8 0.0 3.4e-07 30.0 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 KEY73846.1 - 3.8e-07 29.9 0.1 6.4e-05 22.7 0.0 2.7 1 1 1 2 2 2 2 TAP-like protein Abhydrolase_6 PF12697.2 KEY73846.1 - 0.00082 19.3 0.5 0.0027 17.6 0.2 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF2724 PF10893.3 KEY73846.1 - 0.1 12.4 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) TPR_10 PF13374.1 KEY73847.1 - 6e-24 83.2 0.0 2.7e-14 52.5 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEY73847.1 - 3.9e-21 74.7 0.0 2.7e-13 49.6 0.0 1.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEY73847.1 - 4.7e-05 22.8 0.2 0.0019 17.8 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEY73847.1 - 0.00018 21.0 0.7 0.011 15.4 0.1 2.8 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.12 KEY73847.1 - 0.00028 20.5 0.9 0.073 13.0 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEY73847.1 - 0.00045 20.2 0.2 0.047 13.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Rab5-bind PF09311.6 KEY73847.1 - 0.001 18.9 0.0 0.25 11.2 0.0 2.1 1 1 1 2 2 2 2 Rabaptin-like protein TPR_1 PF00515.23 KEY73847.1 - 0.0013 18.2 1.0 0.13 11.8 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.7 KEY73847.1 - 0.0047 16.7 0.0 2.5 7.9 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.9 KEY73847.1 - 0.014 15.8 0.0 0.05 14.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KEY73847.1 - 0.07 13.2 0.2 11 6.2 0.0 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KEY73847.1 - 0.1 12.3 0.1 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_61 PF03443.9 KEY73848.1 - 8.7e-43 146.6 0.0 1.2e-42 146.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KEY73848.1 - 2.4e-11 43.0 13.1 8.6e-11 41.3 9.1 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KEY73848.1 - 1.2 9.2 9.2 3.1 7.9 6.3 1.8 1 0 0 1 1 1 0 Toxin 7 DDE_Tnp_1_7 PF13843.1 KEY73849.1 - 1.8e-14 53.5 0.0 1.4e-09 37.4 0.0 2.0 1 1 1 2 2 2 2 Transposase IS4 HTH_30 PF13556.1 KEY73851.1 - 0.58 9.7 3.5 0.76 9.4 0.3 2.8 3 0 0 3 3 3 0 PucR C-terminal helix-turn-helix domain DNA_ligase_A_N PF04675.9 KEY73852.1 - 8.6e-12 45.2 0.1 1.7e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.16 KEY73852.1 - 3.5e-10 39.6 0.0 2.2e-06 27.2 0.0 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Antimicrobial_2 PF08023.7 KEY73852.1 - 0.034 14.4 1.8 0.084 13.2 1.2 1.7 1 0 0 1 1 1 0 Frog antimicrobial peptide Tannase PF07519.6 KEY73855.1 - 7.5e-96 321.6 2.3 8.9e-96 321.4 1.6 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 KEY73855.1 - 1.1e-06 28.0 0.2 0.004 16.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KEY73855.1 - 9.6e-06 25.6 0.0 3.2e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Period_C PF12114.3 KEY73855.1 - 0.026 14.1 0.0 0.43 10.1 0.0 2.1 2 0 0 2 2 2 0 Period protein 2/3C-terminal region PHR PF08005.7 KEY73855.1 - 0.11 12.6 0.3 0.23 11.6 0.2 1.5 1 0 0 1 1 1 0 PHR domain Glyco_transf_28 PF03033.15 KEY73856.1 - 1.3e-17 63.8 0.1 2.4e-17 62.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Zn_clus PF00172.13 KEY73857.1 - 2.8e-09 36.7 10.5 4.6e-09 36.0 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2797 PF10977.3 KEY73857.1 - 0.38 10.3 3.4 0.61 9.6 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Defensin_4 PF07936.7 KEY73858.1 - 0.013 15.1 2.4 0.057 13.0 0.2 2.4 2 1 0 2 2 2 0 Potassium-channel blocking toxin Nucleoplasmin PF03066.10 KEY73860.1 - 0.0087 15.5 2.0 0.011 15.2 1.4 1.2 1 0 0 1 1 1 1 Nucleoplasmin LysR_substrate PF03466.15 KEY73860.1 - 0.019 14.0 0.9 0.034 13.2 0.6 1.4 1 0 0 1 1 1 0 LysR substrate binding domain Zea_mays_MuDR PF05928.6 KEY73860.1 - 1 8.7 4.5 1.4 8.2 3.1 1.2 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) 2-Hacid_dh PF00389.25 KEY73861.1 - 0.05 13.0 0.0 0.065 12.7 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain zf-C2H2_4 PF13894.1 KEY73861.1 - 1.5 9.3 5.8 0.73 10.3 0.9 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Ank_2 PF12796.2 KEY73862.1 - 2.5e-152 495.6 48.9 2.9e-20 72.4 0.6 6.8 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 KEY73862.1 - 6.2e-80 259.2 54.9 2.8e-06 26.8 0.2 14.3 14 0 0 14 14 14 13 Ankyrin repeat Ank_4 PF13637.1 KEY73862.1 - 8.4e-52 172.6 30.7 7.7e-07 29.4 0.2 12.2 1 1 12 13 13 13 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY73862.1 - 2.1e-46 151.2 29.0 0.0057 16.7 0.0 14.3 14 0 0 14 14 14 13 Ankyrin repeat Ank_5 PF13857.1 KEY73862.1 - 6.5e-41 137.4 36.5 2.9e-05 24.1 0.5 12.1 1 1 12 13 13 13 13 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 KEY73862.1 - 6e-09 35.2 0.1 1.6e-08 33.8 0.1 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 KEY73862.1 - 1.2e-07 31.5 0.0 2.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain gag-asp_proteas PF13975.1 KEY73862.1 - 1.2e-07 31.3 16.3 1.6 8.6 0.0 10.6 12 0 0 12 12 12 1 gag-polyprotein putative aspartyl protease AAA_16 PF13191.1 KEY73862.1 - 3.8e-06 27.0 0.0 1.1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 KEY73862.1 - 0.00036 19.4 0.0 0.00065 18.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 KEY73862.1 - 0.01 15.5 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 KEY73862.1 - 0.06 13.4 0.0 0.23 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF1843 PF08898.5 KEY73862.1 - 7.4 6.6 27.1 24 5.0 0.0 8.7 6 2 5 11 11 11 0 Domain of unknown function (DUF1843) Mem_trans PF03547.13 KEY73863.1 - 4e-24 84.6 0.0 6.2e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 Membrane transport protein NapE PF06796.6 KEY73863.1 - 0.044 13.0 4.5 5.7 6.3 1.9 2.8 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE Fungal_trans PF04082.13 KEY73864.1 - 9.7e-09 34.4 0.0 1.6e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY73864.1 - 0.00012 21.8 18.8 0.00024 20.9 13.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M28 PF04389.12 KEY73865.1 - 4.9e-29 101.3 0.0 7.2e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KEY73865.1 - 1.2e-17 63.4 0.1 2.1e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 KEY73865.1 - 5.5e-05 22.7 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF1691 PF07950.6 KEY73865.1 - 0.038 13.9 0.0 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) adh_short PF00106.20 KEY73866.1 - 1.2e-18 67.6 0.0 1.4e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY73866.1 - 6e-08 32.7 0.0 6.9e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEY73866.1 - 3.3e-07 29.9 0.0 4.2e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 KEY73866.1 - 0.00019 21.8 0.9 0.00029 21.2 0.0 1.8 2 0 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 KEY73866.1 - 0.00023 20.8 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KEY73866.1 - 0.00024 21.1 0.0 0.00056 20.0 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 KEY73866.1 - 0.00044 19.2 0.0 0.0008 18.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 KEY73866.1 - 0.0063 16.1 0.0 0.014 15.0 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KEY73866.1 - 0.0078 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_Gly3P_dh_N PF01210.18 KEY73866.1 - 0.033 13.9 0.1 0.059 13.0 0.1 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NmrA PF05368.8 KEY73866.1 - 0.072 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Abhydrolase_6 PF12697.2 KEY73867.1 - 6.8e-11 42.4 0.3 1.4e-10 41.4 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY73867.1 - 0.0049 16.4 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY73867.1 - 0.014 15.1 0.2 0.074 12.8 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Cytadhesin_P30 PF07271.6 KEY73867.1 - 0.22 10.7 0.1 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 5HT_transporter PF03491.8 KEY73867.1 - 0.23 11.5 2.0 0.49 10.5 1.4 1.5 1 0 0 1 1 1 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus Cu-oxidase_3 PF07732.10 KEY73868.1 - 8e-46 154.5 0.9 8e-46 154.5 0.6 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 KEY73868.1 - 2.4e-29 102.3 0.1 9.6e-28 97.0 0.0 2.5 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KEY73868.1 - 6.7e-11 41.8 6.0 0.00023 20.6 0.8 4.2 3 1 0 3 3 3 2 Multicopper oxidase DUF3357 PF11837.3 KEY73868.1 - 0.14 12.0 0.7 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Mucin PF01456.12 KEY73868.1 - 0.15 11.7 12.3 0.15 11.7 7.4 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein adh_short PF00106.20 KEY73869.1 - 1.1e-16 61.1 0.2 2.5e-16 60.0 0.2 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY73869.1 - 6.1e-08 32.5 0.3 1.1e-07 31.6 0.2 1.4 1 0 0 1 1 1 1 KR domain Glyco_hydro_61 PF03443.9 KEY73871.1 - 3.5e-59 200.2 0.1 4.5e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF3237 PF11578.3 KEY73872.1 - 1.9e-34 118.1 0.1 2.6e-34 117.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Tyrosinase PF00264.15 KEY73873.1 - 1.6e-42 146.1 2.4 1.6e-42 146.1 1.7 3.9 2 1 0 2 2 2 1 Common central domain of tyrosinase UDPGT PF00201.13 KEY73874.1 - 1.5e-06 27.0 0.0 2.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 KEY73874.1 - 7e-05 22.6 0.0 0.00026 20.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.11 KEY73874.1 - 0.00049 19.7 0.0 0.00096 18.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ketoacyl-synt PF00109.21 KEY73875.1 - 4.1e-74 249.2 1.6 4.8e-74 249.0 0.2 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Carn_acyltransf PF00755.15 KEY73875.1 - 3.5e-71 240.0 0.0 4.5e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Acyl_transf_1 PF00698.16 KEY73875.1 - 2.9e-57 194.4 2.1 6.5e-57 193.2 1.4 1.6 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KEY73875.1 - 1.6e-47 161.4 0.1 1.6e-47 161.4 0.1 3.0 3 0 0 3 3 3 1 KR domain PS-DH PF14765.1 KEY73875.1 - 1e-41 143.0 0.0 5e-40 137.5 0.0 2.5 1 1 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KEY73875.1 - 7.5e-41 139.8 3.9 2.3e-40 138.2 0.1 3.2 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KEY73875.1 - 4.7e-34 116.7 0.2 1.8e-33 114.8 0.2 2.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KEY73875.1 - 3.6e-17 62.1 0.1 6.3e-16 58.1 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY73875.1 - 1.7e-10 41.8 0.0 1.7e-08 35.4 0.0 3.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KEY73875.1 - 9e-07 28.7 0.0 3.2e-06 26.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 KEY73875.1 - 1.8e-05 24.4 0.0 4.6e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KEY73875.1 - 0.0092 16.2 0.1 0.024 14.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 KEY73875.1 - 0.01 16.2 0.0 0.063 13.7 0.0 2.4 2 0 0 2 2 1 0 Methyltransferase domain Thiolase_N PF00108.18 KEY73875.1 - 0.04 12.8 2.8 0.066 12.1 0.1 2.2 2 0 0 2 2 2 0 Thiolase, N-terminal domain Methyltransf_11 PF08241.7 KEY73875.1 - 0.054 13.9 0.0 0.31 11.5 0.0 2.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KEY73875.1 - 0.08 12.5 0.0 0.39 10.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain UDPGT PF00201.13 KEY73876.1 - 1.2e-08 34.0 0.0 5.8e-08 31.7 0.0 1.8 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 KEY73876.1 - 0.0015 18.2 0.0 0.0057 16.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain Acyl_transf_3 PF01757.17 KEY73877.1 - 2.8e-20 72.4 13.6 3.7e-20 72.0 9.4 1.1 1 0 0 1 1 1 1 Acyltransferase family Amidohydro_2 PF04909.9 KEY73878.1 - 7.5e-24 84.7 0.0 9.1e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase p450 PF00067.17 KEY73879.1 - 7.9e-78 262.0 0.0 1e-77 261.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.14 KEY73880.1 - 3.1e-61 207.1 0.0 4.1e-61 206.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY73880.1 - 9e-35 120.0 0.0 1.5e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KEY73880.1 - 1.2e-07 30.9 0.4 0.0011 17.9 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KEY73880.1 - 2.6e-05 24.1 0.1 8.2e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEY73880.1 - 0.00023 20.1 0.1 0.026 13.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEY73880.1 - 0.00085 18.3 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KEY73880.1 - 0.0014 18.7 0.1 0.28 11.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEY73880.1 - 0.016 14.3 0.1 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KEY73880.1 - 0.065 11.6 0.0 0.1 11.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 KEY73880.1 - 0.13 10.8 0.1 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.1 KEY73880.1 - 0.18 10.7 0.0 8.7 5.1 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 KEY73880.1 - 0.19 10.7 0.2 0.46 9.4 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Methyltransf_18 PF12847.2 KEY73881.1 - 1.8e-14 54.2 0.0 3.1e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY73881.1 - 5.2e-13 48.8 0.0 7e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY73881.1 - 9.3e-13 48.4 0.0 1.9e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY73881.1 - 5.1e-11 42.9 0.0 9.7e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY73881.1 - 1.8e-10 40.7 0.0 2.8e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY73881.1 - 4.1e-10 39.9 0.0 7.3e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY73881.1 - 1.1e-09 38.3 0.0 2.6e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY73881.1 - 3.5e-08 33.0 0.0 4.8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KEY73881.1 - 3.9e-07 29.4 0.0 5.6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KEY73881.1 - 1.7e-06 27.3 0.1 3.1e-06 26.4 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.7 KEY73881.1 - 5e-05 22.7 0.0 7.9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase CMAS PF02353.15 KEY73881.1 - 6.1e-05 22.2 0.0 7.4e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 KEY73881.1 - 0.00015 21.2 0.0 0.00022 20.6 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.6 KEY73881.1 - 0.00039 19.2 0.0 0.00093 17.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_15 PF09445.5 KEY73881.1 - 0.00083 18.9 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase NNMT_PNMT_TEMT PF01234.12 KEY73881.1 - 0.0039 16.2 0.0 1.5 7.7 0.0 2.1 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Cons_hypoth95 PF03602.10 KEY73881.1 - 0.0041 16.5 0.0 0.01 15.2 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_24 PF13578.1 KEY73881.1 - 0.0064 17.3 0.0 0.012 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KEY73881.1 - 0.015 14.3 0.1 0.025 13.6 0.0 1.4 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_3 PF01596.12 KEY73881.1 - 0.03 13.3 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_2 PF00891.13 KEY73881.1 - 0.044 12.9 0.1 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Rsm22 PF09243.5 KEY73881.1 - 0.062 12.3 0.0 0.083 11.9 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 PhzC-PhzF PF02567.11 KEY73882.1 - 9.6e-44 149.6 0.0 1.1e-43 149.4 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Cation_ATPase_C PF00689.16 KEY73883.1 - 0.011 15.2 1.0 0.011 15.2 0.7 2.8 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Peptidase_M56 PF05569.6 KEY73883.1 - 0.046 12.6 6.8 0.11 11.3 4.8 1.6 1 1 0 1 1 1 0 BlaR1 peptidase M56 ADH_zinc_N_2 PF13602.1 KEY73885.1 - 1.2e-15 58.5 0.0 2.2e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KEY73885.1 - 1.2e-10 41.0 0.0 2.3e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY73885.1 - 2.2e-07 30.6 0.8 7.9e-07 28.8 0.0 2.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain DFP PF04127.10 KEY73885.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein BNR_2 PF13088.1 KEY73886.1 - 1.1e-06 28.2 1.1 1.6e-06 27.6 0.6 1.5 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 KEY73886.1 - 0.012 15.3 0.2 0.078 12.8 0.1 2.5 1 0 0 1 1 1 0 BNR/Asp-box repeat HET PF06985.6 KEY73887.1 - 2.9e-32 111.7 0.1 5.1e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.2 KEY73888.1 - 0.0089 15.7 0.2 0.0089 15.7 0.2 2.1 2 0 0 2 2 2 1 F-box-like Transp_cyt_pur PF02133.10 KEY73889.1 - 1e-69 235.1 43.8 1.2e-69 234.9 30.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ycf66_N PF07444.6 KEY73889.1 - 0.14 11.8 2.2 0.29 10.8 0.3 2.4 2 1 0 2 2 2 0 Ycf66 protein N-terminus Abhydrolase_6 PF12697.2 KEY73890.1 - 2.7e-25 89.6 0.1 3.2e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY73890.1 - 5.7e-12 45.6 0.0 1.5e-11 44.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KEY73890.1 - 6.5e-09 35.5 0.0 2e-08 33.9 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 KEY73890.1 - 1.7e-08 34.3 0.3 6.5e-07 29.1 0.2 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 KEY73890.1 - 0.00036 20.3 0.0 0.00063 19.5 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Bac_luciferase PF00296.15 KEY73891.1 - 2.5e-56 191.0 0.1 3.5e-56 190.5 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF1446 PF07287.6 KEY73892.1 - 5.1e-123 410.1 0.1 6.8e-123 409.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Fungal_trans PF04082.13 KEY73892.1 - 3e-28 98.3 0.1 5.1e-28 97.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY73892.1 - 0.00021 21.1 3.1 0.0005 19.9 2.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phage_Integr_2 PF13009.1 KEY73892.1 - 0.052 12.4 0.0 0.14 11.0 0.0 1.6 2 0 0 2 2 2 0 Putative phage integrase ENOD93 PF03386.9 KEY73892.1 - 0.095 12.4 0.8 0.24 11.1 0.5 1.6 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein Sulfate_tra_GLY PF13792.1 KEY73893.1 - 0.0083 15.7 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif FUSC PF04632.7 KEY73893.1 - 0.035 12.5 0.1 0.051 12.0 0.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Amidohydro_2 PF04909.9 KEY73894.1 - 1.6e-27 96.7 0.4 1.9e-27 96.5 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase Isochorismatase PF00857.15 KEY73896.1 - 6e-17 62.1 0.0 8.2e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF867 PF05908.6 KEY73896.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF867) COesterase PF00135.23 KEY73897.1 - 1.1e-67 229.0 0.1 6.2e-67 226.5 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEY73897.1 - 0.0008 19.0 3.0 0.0014 18.2 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEY73897.1 - 0.0024 17.1 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family MMR_HSR1 PF01926.18 KEY73898.1 - 1.4e-07 31.4 0.0 5.4e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 KEY73898.1 - 2.9e-05 23.2 0.4 6.9e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 KEY73898.1 - 0.00088 19.7 0.1 0.021 15.3 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein IIGP PF05049.8 KEY73898.1 - 0.0012 17.6 0.1 0.0026 16.6 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.13 KEY73898.1 - 0.0019 17.4 0.1 0.013 14.7 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 KEY73898.1 - 0.0051 16.0 0.1 0.015 14.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KEY73898.1 - 0.0099 15.7 9.3 0.19 11.5 0.0 3.4 2 2 1 3 3 3 2 Dynamin family IncA PF04156.9 KEY73898.1 - 0.34 10.4 12.6 0.59 9.7 8.7 1.4 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 KEY73898.1 - 0.7 8.7 9.4 1 8.2 6.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Exonuc_VII_L PF02601.10 KEY73898.1 - 5.2 6.1 11.9 8.6 5.4 8.2 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit MMR_HSR1 PF01926.18 KEY73899.1 - 1.1e-08 35.0 0.0 3.5e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 KEY73899.1 - 6.9e-07 28.5 0.0 6.9e-07 28.5 0.0 2.9 2 1 1 3 3 3 1 AIG1 family AAA_10 PF12846.2 KEY73899.1 - 0.0018 17.7 2.8 0.54 9.6 0.1 2.2 2 0 0 2 2 2 2 AAA-like domain Miro PF08477.8 KEY73899.1 - 0.0044 17.5 0.0 0.016 15.7 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 KEY73899.1 - 0.0069 15.5 0.1 0.021 13.9 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KEY73899.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 KEY73899.1 - 0.017 14.0 0.0 0.035 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF1953 PF09196.5 KEY73899.1 - 0.028 14.1 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1953) DUF2317 PF10079.4 KEY73899.1 - 0.029 12.9 10.1 0.046 12.3 7.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) FeoB_N PF02421.13 KEY73899.1 - 0.071 12.3 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B GTP_EFTU PF00009.22 KEY73899.1 - 0.072 12.5 0.4 3 7.2 0.2 2.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF87 PF01935.12 KEY73899.1 - 0.086 12.6 0.1 0.086 12.6 0.1 2.6 2 1 0 2 2 1 0 Domain of unknown function DUF87 Dynamin_N PF00350.18 KEY73899.1 - 0.093 12.5 16.1 0.44 10.3 0.0 4.1 2 2 1 3 3 2 0 Dynamin family FtsK_SpoIIIE PF01580.13 KEY73899.1 - 0.22 11.0 0.0 0.22 11.0 0.0 2.6 2 1 0 2 2 1 0 FtsK/SpoIIIE family ABC_tran PF00005.22 KEY73899.1 - 0.69 10.2 0.0 0.69 10.2 0.0 3.0 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 KEY73899.1 - 1.4 9.2 0.0 1.4 9.2 0.0 2.6 2 1 0 2 2 1 0 AAA domain POX PF07526.6 KEY73899.1 - 6.1 7.0 13.8 0.18 12.0 4.1 2.3 1 1 1 2 2 2 0 Associated with HOX MFS_1 PF07690.11 KEY73900.1 - 3.6e-22 78.5 47.8 1.8e-11 43.3 17.2 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily RCR PF12273.3 KEY73900.1 - 0.072 13.6 1.5 0.21 12.1 0.0 2.2 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red TRI12 PF06609.8 KEY73900.1 - 0.12 10.5 24.5 0.72 7.9 17.0 2.2 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Abhydrolase_6 PF12697.2 KEY73901.1 - 1.6e-22 80.5 0.2 1.9e-22 80.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY73901.1 - 7e-06 25.8 0.0 9.9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KEY73904.1 - 6.9e-21 74.0 0.0 2.1e-20 72.5 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 KEY73904.1 - 1.7e-10 40.8 0.0 2.9e-10 40.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEY73904.1 - 4.6e-07 29.9 0.1 1e-06 28.8 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY73904.1 - 0.02 14.6 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family K_oxygenase PF13434.1 KEY73905.1 - 5.4e-05 22.2 0.3 0.0042 16.0 0.0 2.7 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KEY73905.1 - 0.02 14.9 0.0 0.069 13.2 0.0 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEY73905.1 - 0.035 12.3 0.4 0.081 11.1 0.0 1.7 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Shikimate_DH PF01488.15 KEY73905.1 - 0.044 13.8 0.0 5.6 7.0 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DUF4441 PF14536.1 KEY73905.1 - 0.11 12.5 1.4 2.7 7.9 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) DDE_Tnp_1_7 PF13843.1 KEY73909.1 - 1.2e-28 100.2 0.0 1.3e-28 100.0 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 Fungal_trans_2 PF11951.3 KEY73910.1 - 0.0024 16.5 0.0 0.0035 15.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pectate_lyase PF03211.8 KEY73911.1 - 6e-76 254.6 0.2 6.8e-76 254.4 0.1 1.0 1 0 0 1 1 1 1 Pectate lyase PuR_N PF09182.5 KEY73913.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal p450 PF00067.17 KEY73915.1 - 1.7e-73 247.7 0.0 2e-73 247.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 KEY73917.1 - 4.2e-119 398.0 27.8 4.9e-119 397.8 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY73917.1 - 1.9e-23 82.7 36.1 4e-20 71.8 18.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEY73917.1 - 3.2e-09 35.6 27.3 6.7e-05 21.4 6.9 3.6 3 1 0 3 3 3 3 MFS/sugar transport protein Ferric_reduct PF01794.14 KEY73918.1 - 4e-17 62.4 21.2 4e-17 62.4 14.7 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KEY73918.1 - 3.4e-10 39.7 0.0 0.00021 21.1 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.7 KEY73918.1 - 2.1e-06 27.7 0.0 0.0033 17.3 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain MFS_1 PF07690.11 KEY73919.1 - 5.5e-35 120.7 37.8 5.5e-35 120.7 26.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TMEM169 PF15052.1 KEY73919.1 - 0.09 12.6 1.7 0.31 10.9 0.5 2.3 2 0 0 2 2 2 0 TMEM169 protein family GFA PF04828.9 KEY73920.1 - 5.5e-14 51.8 4.1 1.1e-11 44.4 2.9 2.1 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Aldo_ket_red PF00248.16 KEY73921.1 - 2.9e-45 154.2 0.0 3.6e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Exonuc_VII_S PF02609.11 KEY73922.1 - 0.093 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Exonuclease VII small subunit zf-C2H2 PF00096.21 KEY73922.1 - 2 8.9 7.7 0.72 10.3 1.4 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type TPR_12 PF13424.1 KEY73924.1 - 3.7e-28 97.2 10.2 1.8e-14 53.3 0.9 3.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 KEY73924.1 - 2.8e-19 68.3 7.7 1.6e-09 37.4 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.17 KEY73924.1 - 1.8e-10 40.1 0.0 2.8e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain PNP_UDP_1 PF01048.15 KEY73924.1 - 1.3e-06 27.5 3.7 1.3e-05 24.3 2.6 2.2 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.1 KEY73924.1 - 2e-06 27.9 0.0 6e-05 23.1 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain TPR_11 PF13414.1 KEY73924.1 - 3.3e-06 26.6 3.4 0.0004 19.9 0.8 3.5 2 1 1 3 3 3 2 TPR repeat AAA_22 PF13401.1 KEY73924.1 - 0.00024 21.2 0.0 0.0021 18.2 0.0 2.6 3 1 0 3 3 3 1 AAA domain TPR_16 PF13432.1 KEY73924.1 - 0.0013 19.3 0.1 0.0066 17.0 0.0 2.4 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEY73924.1 - 0.0013 18.3 2.0 3.1 7.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEY73924.1 - 0.0044 16.5 6.5 0.12 12.0 0.6 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat NACHT PF05729.7 KEY73924.1 - 0.006 16.2 0.0 0.022 14.4 0.0 1.9 2 0 0 2 2 2 1 NACHT domain TPR_17 PF13431.1 KEY73924.1 - 0.0069 16.5 3.8 0.29 11.4 0.0 4.1 5 0 0 5 5 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KEY73924.1 - 0.14 12.2 1.2 0.85 9.7 0.2 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Ras PF00071.17 KEY73925.1 - 6.2e-48 162.2 0.0 9.8e-48 161.5 0.0 1.3 1 0 0 1 1 1 1 Ras family Ank_2 PF12796.2 KEY73925.1 - 2.7e-45 152.6 8.7 4.1e-19 68.7 0.0 3.4 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEY73925.1 - 1.2e-27 94.2 19.4 2.8e-06 26.8 0.1 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 KEY73925.1 - 1.3e-22 77.5 6.6 3.3e-05 23.7 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 KEY73925.1 - 4.7e-21 74.3 15.4 1e-06 28.7 0.1 6.3 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEY73925.1 - 1.3e-20 73.3 7.4 7.8e-08 32.6 0.1 5.4 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Miro PF08477.8 KEY73925.1 - 1.5e-14 54.4 0.0 3.2e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein DIOX_N PF14226.1 KEY73926.1 - 7.6e-20 71.5 0.0 1.5e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KEY73926.1 - 8.9e-12 45.1 0.0 1.4e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 KEY73927.1 - 1.7e-25 89.4 27.2 1.7e-25 89.4 18.9 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily COesterase PF00135.23 KEY73928.1 - 1.7e-99 334.0 0.0 2.1e-99 333.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEY73928.1 - 5.8e-07 29.2 0.2 9.6e-07 28.5 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold adh_short PF00106.20 KEY73929.1 - 1.9e-07 31.1 0.0 4.2e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY73929.1 - 3.8e-06 26.6 0.0 7.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Abhydrolase_8 PF06259.7 KEY73929.1 - 0.14 11.6 0.1 0.28 10.6 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase HET PF06985.6 KEY73931.1 - 9.6e-20 71.1 6.8 1.3e-16 61.0 0.7 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF1273 PF06908.6 KEY73931.1 - 0.039 13.5 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) DUF2927 PF11150.3 KEY73932.1 - 0.13 11.8 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2927) Zn_clus PF00172.13 KEY73933.1 - 2.1e-08 33.9 8.6 3.3e-08 33.3 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rtf2 PF04641.7 KEY73934.1 - 1.2e-52 178.7 2.4 1.7e-52 178.1 1.7 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 KEY73934.1 - 3.8e-05 23.3 0.0 0.0001 21.9 0.0 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KEY73934.1 - 0.0011 18.5 0.1 0.0017 17.9 0.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEY73934.1 - 0.0014 18.4 0.1 0.0091 15.8 0.2 2.1 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KEY73934.1 - 0.0027 17.4 0.1 0.0046 16.6 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEY73934.1 - 0.036 14.0 0.5 0.1 12.6 0.4 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.4 KEY73934.1 - 0.037 13.7 3.5 1.7 8.4 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RING_4 PF14570.1 KEY73934.1 - 0.12 11.9 0.2 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.5 KEY73934.1 - 0.18 11.7 1.1 0.47 10.4 0.8 1.7 1 0 0 1 1 1 0 Zinc ribbon domain FGF-BP1 PF06473.7 KEY73934.1 - 0.87 9.1 7.5 1.4 8.4 5.2 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) YycI PF09648.5 KEY73934.1 - 1.3 8.4 6.0 1.7 8.0 4.1 1.2 1 0 0 1 1 1 0 YycH protein UFD1 PF03152.9 KEY73937.1 - 3.6e-24 84.8 0.0 2.2e-18 66.0 0.0 3.2 3 1 0 3 3 3 2 Ubiquitin fusion degradation protein UFD1 RhgB_N PF09284.5 KEY73939.1 - 4.5e-101 337.3 2.1 4.5e-101 337.3 1.5 1.7 2 0 0 2 2 2 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 KEY73939.1 - 5.7e-54 182.2 0.0 1.5e-53 180.8 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 KEY73939.1 - 1.9e-16 59.9 1.7 1.9e-16 59.9 1.2 2.0 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 KEY73939.1 - 0.00028 20.8 1.7 0.00028 20.8 1.2 3.4 4 0 0 4 4 4 1 Carboxypeptidase regulatory-like domain DUF3823 PF12866.2 KEY73939.1 - 0.0015 18.1 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3823) Glyco_hydro_71 PF03659.9 KEY73940.1 - 2.3e-120 401.6 0.6 2.8e-120 401.3 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Ank_2 PF12796.2 KEY73941.1 - 7.3e-86 282.6 10.8 3.3e-21 75.4 0.1 6.5 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KEY73941.1 - 6.8e-74 240.2 7.3 1.4e-08 34.1 0.0 10.4 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 KEY73941.1 - 3e-57 190.0 17.0 9.6e-13 48.2 0.2 9.0 3 1 5 9 9 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY73941.1 - 2.3e-52 169.7 7.5 3.2e-05 23.7 0.0 10.9 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 KEY73941.1 - 7.5e-41 137.2 17.0 2.7e-10 40.1 0.4 7.3 3 2 5 8 8 8 7 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 KEY73941.1 - 5e-14 51.8 0.0 1.2e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 KEY73941.1 - 5.4e-08 32.6 0.0 1.9e-07 30.9 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEY73941.1 - 0.00038 20.4 0.1 0.0025 17.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 KEY73941.1 - 0.014 15.6 0.0 0.044 14.0 0.0 1.8 2 0 0 2 2 1 0 ABC transporter AAA_22 PF13401.1 KEY73941.1 - 0.022 14.8 0.0 0.078 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KEY73941.1 - 0.073 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF3157 PF11355.3 KEY73941.1 - 2 7.6 5.5 3.5 6.8 0.4 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3157) MR_MLE PF01188.16 KEY73942.1 - 0.072 13.6 0.1 4.4 7.8 0.1 2.6 2 1 1 3 3 3 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Jag_N PF14804.1 KEY73942.1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Jag N-terminus GTP_EFTU PF00009.22 KEY73943.1 - 3.4e-05 23.3 0.0 0.06 12.7 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Arf PF00025.16 KEY73943.1 - 9.7e-05 21.6 0.1 0.006 15.8 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEY73943.1 - 0.16 11.0 0.3 0.32 10.0 0.0 1.6 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region SUZ PF12752.2 KEY73945.1 - 0.4 11.2 3.6 0.57 10.7 2.5 1.2 1 0 0 1 1 1 0 SUZ domain DDE_Tnp_1_7 PF13843.1 KEY73949.1 - 1.8e-10 40.4 0.0 9.7e-09 34.7 0.0 2.1 1 1 1 2 2 2 2 Transposase IS4 Ank_2 PF12796.2 KEY73950.1 - 5.4e-44 148.4 14.3 2.5e-17 62.9 1.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEY73950.1 - 1.8e-29 100.0 11.8 6.2e-05 22.5 0.0 6.8 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.1 KEY73950.1 - 3.1e-19 67.1 8.4 0.015 15.4 0.1 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 KEY73950.1 - 1.8e-16 59.7 6.5 3e-05 24.1 0.2 6.2 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEY73950.1 - 4.4e-16 58.9 2.2 0.00024 21.5 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) NACHT PF05729.7 KEY73950.1 - 4.4e-10 39.4 0.1 8.9e-10 38.4 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEY73950.1 - 1.8e-07 31.3 0.0 7.5e-07 29.3 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain PNP_UDP_1 PF01048.15 KEY73950.1 - 1.1e-06 27.8 0.5 3.3e-06 26.2 0.3 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.1 KEY73950.1 - 4.5e-05 23.5 0.0 0.00013 22.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KEY73950.1 - 0.0019 17.0 0.0 0.0035 16.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 KEY73950.1 - 0.0042 16.8 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 KEY73950.1 - 0.034 14.0 0.1 0.75 9.7 0.1 2.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KEY73950.1 - 0.1 12.7 0.0 0.33 11.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HET PF06985.6 KEY73952.1 - 2.2e-29 102.3 0.0 3.6e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pro_CA PF00484.14 KEY73953.1 - 3e-09 37.0 0.0 2.5e-08 34.0 0.0 2.0 1 1 0 1 1 1 1 Carbonic anhydrase NmrA PF05368.8 KEY73954.1 - 2.3e-20 72.8 0.0 4.4e-20 71.9 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY73954.1 - 8.2e-05 22.6 0.1 0.00032 20.7 0.0 2.0 2 1 0 3 3 3 1 NADH(P)-binding KR PF08659.5 KEY73954.1 - 0.0013 18.4 0.7 0.0021 17.7 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KEY73954.1 - 0.042 13.7 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.16 KEY73954.1 - 0.065 12.6 0.5 0.37 10.1 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEY73954.1 - 0.091 11.4 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HET PF06985.6 KEY73955.1 - 0.00018 21.7 0.0 0.00036 20.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 KEY73956.1 - 7.7e-15 54.3 3.1 1.5e-12 46.8 2.2 2.9 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 KEY73957.1 - 2.7e-19 69.6 0.1 3.4e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY73957.1 - 4.8e-09 36.3 0.0 6.4e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY73957.1 - 6.9e-07 29.0 0.0 9.8e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KEY73957.1 - 0.0021 18.1 0.1 0.0098 15.9 0.0 1.9 1 1 1 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 KEY73957.1 - 0.0081 15.3 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 KEY73957.1 - 0.02 14.6 0.2 0.046 13.5 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Fungal_trans PF04082.13 KEY73958.1 - 6.1e-16 58.0 1.4 1.8e-15 56.5 0.6 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain DUF4243 PF14027.1 KEY73959.1 - 3.2e-33 115.5 0.1 3.9e-33 115.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) MerR PF00376.18 KEY73962.1 - 0.04 13.4 0.0 0.088 12.3 0.0 1.6 1 0 0 1 1 1 0 MerR family regulatory protein NUMOD1 PF07453.8 KEY73962.1 - 0.05 13.4 0.2 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 NUMOD1 domain tRNA-synt_2 PF00152.15 KEY73968.1 - 5.5e-88 294.9 0.0 7.6e-88 294.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 KEY73968.1 - 0.0017 17.9 0.1 0.0046 16.5 0.0 1.6 1 1 1 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF883 PF05957.8 KEY73969.1 - 0.4 11.1 10.2 0.15 12.5 3.4 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.13 KEY73969.1 - 1.2 8.9 4.4 1.7 8.4 1.4 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) SseC PF04888.7 KEY73969.1 - 2.6 7.3 29.1 3.4 6.9 20.1 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Fungal_trans PF04082.13 KEY73970.1 - 3e-12 45.9 0.4 5.8e-12 45.0 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY73970.1 - 2.7e-08 33.5 9.4 2.7e-08 33.5 6.5 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_fiss_reg PF05308.6 KEY73970.1 - 0.13 11.5 4.5 0.26 10.6 3.1 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KEY73970.1 - 5.7 6.1 9.1 12 5.0 6.3 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal 3Beta_HSD PF01073.14 KEY73971.1 - 1.1e-10 40.7 0.0 1.7e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KEY73971.1 - 4.5e-10 39.3 0.0 4.6e-07 29.5 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY73971.1 - 7.8e-07 29.2 0.1 1.3e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KEY73971.1 - 2.1e-06 26.8 0.0 3.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KEY73971.1 - 0.00018 21.4 0.1 0.00041 20.3 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 KEY73971.1 - 0.00056 19.0 0.0 0.00076 18.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 KEY73971.1 - 0.00096 18.1 0.1 0.0021 17.0 0.1 1.5 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 KEY73971.1 - 0.0016 17.4 0.0 0.012 14.5 0.1 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.5 KEY73971.1 - 0.008 15.8 0.1 0.018 14.7 0.0 1.6 2 0 0 2 2 2 1 KR domain NmrA PF05368.8 KEY73971.1 - 0.011 14.9 0.1 0.018 14.3 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_3 PF03447.11 KEY73971.1 - 0.13 12.7 0.1 0.38 11.1 0.0 1.8 2 0 0 2 2 1 0 Homoserine dehydrogenase, NAD binding domain MFS_1 PF07690.11 KEY73972.1 - 1.6e-16 60.0 19.7 2.1e-16 59.5 13.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.11 KEY73973.1 - 1.1e-40 139.9 0.1 1.4e-40 139.5 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Homeobox_KN PF05920.6 KEY73974.1 - 2.6e-13 49.4 0.1 2.6e-13 49.4 0.0 2.8 3 0 0 3 3 3 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.11 KEY73974.1 - 5.2e-11 42.2 1.1 0.00027 20.6 0.0 5.4 5 1 0 5 5 5 2 Tc5 transposase DNA-binding domain Homeobox PF00046.24 KEY73974.1 - 2.1e-07 30.4 0.3 8.7e-07 28.4 0.0 2.2 2 0 0 2 2 2 1 Homeobox domain zf-C2H2_4 PF13894.1 KEY73974.1 - 0.00077 19.6 18.9 0.017 15.3 2.1 4.3 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY73974.1 - 0.0046 17.2 2.2 0.0046 17.2 1.5 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type Homez PF11569.3 KEY73974.1 - 0.056 12.5 0.0 0.15 11.1 0.0 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Flo11 PF10182.4 KEY73974.1 - 0.068 12.7 0.7 8.4 5.9 0.0 2.4 2 0 0 2 2 2 0 Flo11 domain VGCC_beta4Aa_N PF12052.3 KEY73974.1 - 0.2 11.5 3.0 0.62 9.9 2.1 1.9 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal zf-C2H2_jaz PF12171.3 KEY73974.1 - 8.3 6.6 6.9 5.1 7.3 0.8 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding MFS_1 PF07690.11 KEY73975.1 - 5.5e-25 87.8 36.3 8.5e-20 70.7 10.4 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY73975.1 - 1.3e-15 56.9 23.3 3.9e-14 52.0 5.9 2.8 2 2 0 2 2 2 2 Sugar (and other) transporter SET PF00856.23 KEY73976.1 - 2e-08 34.6 0.3 2.9e-06 27.6 0.1 2.2 2 0 0 2 2 2 2 SET domain UCR_hinge PF02320.11 KEY73976.1 - 4.8 7.1 8.6 0.43 10.5 0.2 2.6 2 1 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein p450 PF00067.17 KEY73977.1 - 2.8e-57 194.2 0.0 3.7e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KEY73979.1 - 3.6e-79 266.4 0.0 4.5e-79 266.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ELO PF01151.13 KEY73980.1 - 1.2e-59 201.6 18.4 1.4e-59 201.4 12.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family 4HBT_2 PF13279.1 KEY73981.1 - 1.5e-06 28.6 0.0 2.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily MFS_1 PF07690.11 KEY73982.1 - 1.3e-37 129.3 59.5 1.3e-37 129.3 41.2 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily SGL PF08450.7 KEY73983.1 - 0.0019 17.6 0.0 0.015 14.6 0.0 2.2 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region GSDH PF07995.6 KEY73983.1 - 0.0022 17.1 0.1 0.0047 16.0 0.1 1.5 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.16 KEY73983.1 - 0.016 15.1 0.2 2.7 8.0 0.0 3.7 5 0 0 5 5 5 0 NHL repeat 2OG-FeII_Oxy_2 PF13532.1 KEY73984.1 - 5.8e-16 58.8 0.1 1.1e-15 58.0 0.0 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KEY73984.1 - 4.4e-10 39.7 0.0 9.4e-10 38.6 0.0 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily GMC_oxred_N PF00732.14 KEY73985.1 - 1.1e-60 205.2 0.1 1.5e-60 204.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY73985.1 - 4e-35 121.2 0.0 6.3e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KEY73985.1 - 0.00027 19.9 0.1 0.00051 19.0 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KEY73985.1 - 0.00034 19.6 3.3 0.0042 16.0 2.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY73985.1 - 0.005 16.8 0.4 0.015 15.3 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain adh_short PF00106.20 KEY73987.1 - 3.6e-21 75.8 0.5 5.3e-21 75.2 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY73987.1 - 5.9e-13 48.8 0.5 9.3e-13 48.2 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY73987.1 - 0.00056 19.4 0.0 0.00071 19.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY73987.1 - 0.047 13.6 1.6 0.085 12.8 1.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding DUF872 PF05915.7 KEY73988.1 - 0.034 14.0 0.1 0.089 12.6 0.0 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) ECF-ribofla_trS PF07155.7 KEY73988.1 - 0.047 13.4 3.5 0.22 11.2 0.1 2.0 1 1 1 2 2 2 0 ECF-type riboflavin transporter, S component NfeD PF01957.13 KEY73988.1 - 0.064 13.3 0.8 0.27 11.3 0.0 1.9 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding DUF2975 PF11188.3 KEY73988.1 - 0.14 11.8 2.3 2.2 7.9 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) DUF202 PF02656.10 KEY73988.1 - 1.1 9.4 5.7 12 6.1 1.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Glyco_hydro_3 PF00933.16 KEY73989.1 - 3.9e-85 285.4 0.0 5.7e-85 284.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY73989.1 - 3.1e-39 134.8 0.2 1.8e-38 132.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEY73989.1 - 1.3e-24 85.9 0.1 2.8e-24 84.8 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Rieske PF00355.21 KEY73990.1 - 4.4e-08 32.5 0.0 8.7e-08 31.6 0.0 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 KEY73990.1 - 5.2e-05 22.9 0.0 7.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain QLQ PF08880.6 KEY73990.1 - 0.084 12.3 0.5 0.15 11.4 0.4 1.4 1 0 0 1 1 1 0 QLQ Methyltransf_2 PF00891.13 KEY73991.1 - 1.6e-31 109.3 0.0 2.4e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 KEY73991.1 - 7.3e-07 28.8 0.0 2.3e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY73991.1 - 8.7e-05 23.0 0.0 0.00017 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KEY73991.1 - 0.036 13.5 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase TPR_10 PF13374.1 KEY73992.1 - 9e-84 273.3 0.0 4.2e-10 39.2 0.0 10.7 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 KEY73992.1 - 7.4e-69 227.6 0.0 2.1e-15 56.4 0.0 6.5 1 1 6 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.1 KEY73992.1 - 1.2e-28 96.5 0.7 0.00031 20.3 0.0 9.2 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_17 PF13431.1 KEY73992.1 - 1.1e-14 53.3 3.1 0.59 10.4 0.0 8.3 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEY73992.1 - 2.6e-13 48.7 5.4 0.15 12.0 0.0 9.2 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEY73992.1 - 1e-12 47.0 0.0 0.25 11.0 0.0 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEY73992.1 - 4e-12 45.5 1.2 0.0074 15.9 0.0 6.2 5 2 0 5 5 5 2 TPR repeat TPR_14 PF13428.1 KEY73992.1 - 3.8e-11 42.5 8.5 11 6.9 0.0 10.0 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_4 PF07721.9 KEY73992.1 - 7.2e-11 41.4 0.3 19 6.0 0.0 8.9 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEY73992.1 - 4.2e-10 40.0 0.4 0.052 14.2 0.0 6.6 3 2 4 7 7 7 2 Tetratricopeptide repeat DUF2664 PF10867.3 KEY73992.1 - 1.3e-08 35.3 0.0 20 5.9 0.0 7.0 6 1 1 7 7 6 0 Protein of unknown function (DUF2664) TPR_19 PF14559.1 KEY73992.1 - 3.2e-06 27.3 0.7 5.6 7.3 0.0 7.4 4 3 5 9 9 9 1 Tetratricopeptide repeat NACHT PF05729.7 KEY73992.1 - 3.6e-06 26.7 0.0 8.7e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 KEY73992.1 - 1.8e-05 23.7 0.3 0.2 10.5 0.0 3.5 3 1 0 4 4 4 2 NB-ARC domain Apc3 PF12895.2 KEY73992.1 - 4.2e-05 23.5 0.0 0.33 11.1 0.0 5.1 1 1 4 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KEY73992.1 - 0.00038 20.0 0.9 3.4 7.6 0.0 5.6 7 0 0 7 7 6 1 Tetratricopeptide repeat AAA_25 PF13481.1 KEY73992.1 - 0.0022 17.4 0.6 0.042 13.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain TPR_3 PF07720.7 KEY73992.1 - 0.0038 17.0 0.0 1.1e+02 2.7 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR_3 PF13812.1 KEY73992.1 - 0.0069 16.5 0.8 30 5.2 0.0 4.8 5 0 0 5 5 3 0 Pentatricopeptide repeat domain AAA_22 PF13401.1 KEY73992.1 - 0.011 15.9 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Euplotes_phero PF05842.6 KEY73992.1 - 0.042 14.2 0.0 1.3e+02 2.9 0.0 4.8 1 1 5 6 6 6 0 Euplotes octocarinatus mating pheromone protein TPR_6 PF13174.1 KEY73992.1 - 0.092 13.2 13.5 11 6.7 0.0 7.3 9 0 0 9 9 6 0 Tetratricopeptide repeat TPR_5 PF12688.2 KEY73992.1 - 0.099 12.6 0.0 16 5.5 0.0 3.9 2 1 1 4 4 3 0 Tetratrico peptide repeat HTH_Tnp_Tc5 PF03221.11 KEY73993.1 - 0.00011 21.9 0.8 0.00038 20.2 0.1 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 KEY73993.1 - 0.00019 20.6 0.0 0.00027 20.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease PNP_UDP_1 PF01048.15 KEY73994.1 - 2.1e-09 36.7 1.6 1.3e-08 34.1 1.1 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily Transglycosylas PF06737.9 KEY73994.1 - 0.14 12.5 0.2 0.14 12.5 0.1 1.9 2 0 0 2 2 2 0 Transglycosylase-like domain BatA PF07584.6 KEY73995.1 - 0.02 15.0 7.3 0.043 14.0 0.1 4.3 4 0 0 4 4 4 0 Aerotolerance regulator N-terminal DUF4328 PF14219.1 KEY73995.1 - 0.03 13.6 3.2 1.4 8.2 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4328) DUF3753 PF12575.3 KEY73995.1 - 6 6.7 9.7 1.7 8.4 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) DUF946 PF06101.6 KEY73996.1 - 4.4e-14 51.3 1.3 2.3e-11 42.3 0.2 2.1 2 0 0 2 2 2 2 Plant protein of unknown function (DUF946) Sarcoglycan_1 PF04790.8 KEY73996.1 - 0.16 11.1 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein Glyco_hydro_16 PF00722.16 KEY73997.1 - 4.7e-09 35.7 1.4 2e-08 33.7 1.7 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 MFS_1 PF07690.11 KEY73999.1 - 6.4e-20 71.1 19.8 6.4e-20 71.1 13.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4648 PF15505.1 KEY73999.1 - 0.06 13.5 0.0 0.096 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4648) Glyco_transf_36 PF06165.6 KEY74000.1 - 6.1e-21 74.3 0.0 1.3e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 36 GT36_AF PF06205.6 KEY74000.1 - 2.6e-08 33.5 0.0 5.2e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase 36 associated family DUF608 PF04685.8 KEY74000.1 - 1.3e-06 27.4 0.6 2e-06 26.7 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Bac_rhamnosid PF05592.6 KEY74000.1 - 9.5e-05 20.7 0.7 0.00019 19.7 0.2 1.7 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase GDE_C PF06202.9 KEY74000.1 - 0.0013 17.5 0.0 0.0033 16.2 0.0 1.5 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase HET PF06985.6 KEY74001.1 - 9.9e-19 67.8 10.6 1.8e-16 60.5 0.7 2.7 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 KEY74003.1 - 3.1e-16 59.7 0.0 8.6e-16 58.2 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KEY74003.1 - 0.00011 21.7 0.0 0.00024 20.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KEY74003.1 - 0.00018 21.3 0.0 0.00044 20.0 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KEY74003.1 - 0.0029 17.6 0.0 0.0053 16.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KEY74003.1 - 0.012 15.2 0.9 0.12 11.9 0.6 2.4 1 1 0 1 1 1 0 KR domain Eno-Rase_NADH_b PF12242.3 KEY74003.1 - 0.023 14.4 0.1 0.046 13.5 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AlaDh_PNT_C PF01262.16 KEY74003.1 - 0.062 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DFP PF04127.10 KEY74003.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein AAA PF00004.24 KEY74006.1 - 1.7e-16 60.6 0.0 2.9e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEY74006.1 - 0.013 15.6 0.0 0.036 14.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain Utp11 PF03998.8 KEY74007.1 - 3.8e-55 187.3 24.4 4.7e-55 187.0 16.9 1.1 1 0 0 1 1 1 1 Utp11 protein DEAD PF00270.24 KEY74008.1 - 0.098 12.1 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase Cmc1 PF08583.5 KEY74009.1 - 9.2e-16 57.3 4.7 2e-15 56.3 3.3 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like MARVEL PF01284.18 KEY74009.1 - 2.6e-10 40.2 14.1 7.7e-10 38.7 9.7 1.8 1 1 0 1 1 1 1 Membrane-associating domain CHCH PF06747.8 KEY74009.1 - 0.014 15.3 0.8 0.041 13.8 0.5 1.9 1 1 0 1 1 1 0 CHCH domain ADH_N PF08240.7 KEY74010.1 - 1.2e-29 102.2 1.8 1.8e-29 101.6 0.2 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY74010.1 - 1.1e-23 83.2 0.1 1.9e-23 82.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY74010.1 - 5.2e-07 30.6 0.1 1.6e-06 29.0 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KEY74010.1 - 0.0083 16.6 0.0 0.019 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain HI0933_like PF03486.9 KEY74010.1 - 0.0093 14.4 0.3 0.013 13.9 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein AdoHcyase_NAD PF00670.16 KEY74010.1 - 0.015 15.1 0.9 0.46 10.3 0.2 2.6 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KEY74010.1 - 0.059 12.7 0.0 0.093 12.0 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 KEY74010.1 - 0.068 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 KEY74010.1 - 0.12 11.4 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain DUF812 PF05667.6 KEY74011.1 - 0.11 10.9 4.1 0.12 10.8 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF966 PF06136.8 KEY74011.1 - 0.86 8.9 14.8 1 8.6 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CytochromB561_N PF09786.4 KEY74011.1 - 4 5.7 15.8 4.6 5.5 10.9 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Pneumo_att_G PF05539.6 KEY74011.1 - 9.3 5.5 21.0 11 5.2 14.6 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G tRNA-synt_2d PF01409.15 KEY74012.1 - 2.8e-84 282.1 0.0 4.2e-84 281.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 KEY74012.1 - 2.3e-06 26.6 0.2 0.00035 19.4 0.0 3.3 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 KEY74012.1 - 6.4e-06 25.8 0.1 0.00013 21.6 0.0 2.5 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Vps52 PF04129.7 KEY74012.1 - 0.0015 17.1 0.1 0.0022 16.5 0.1 1.2 1 0 0 1 1 1 1 Vps52 / Sac2 family PALP PF00291.20 KEY74013.1 - 1.1e-31 110.2 0.1 1.2e-31 110.0 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CN_hydrolase PF00795.17 KEY74015.1 - 1.2e-27 96.4 0.0 3.4e-27 95.0 0.0 1.8 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 KEY74015.1 - 2.8e-22 78.8 0.0 8.7e-22 77.1 0.0 1.7 1 1 0 1 1 1 1 NAD synthase DUF3129 PF11327.3 KEY74016.1 - 9.9e-20 71.1 14.2 9.9e-20 71.1 9.8 3.6 2 2 0 2 2 2 1 Protein of unknown function (DUF3129) NOA36 PF06524.7 KEY74016.1 - 4 6.6 15.5 5.8 6.0 10.7 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 KEY74016.1 - 6.2 4.7 8.6 8.9 4.2 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein ADH_zinc_N PF00107.21 KEY74018.1 - 2.7e-20 72.2 0.1 4.4e-20 71.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY74018.1 - 6.9e-12 46.3 0.3 1e-10 42.6 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Aa_trans PF01490.13 KEY74019.1 - 3.2e-50 170.8 34.2 3.6e-50 170.6 23.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3593 PF12159.3 KEY74019.1 - 0.025 14.3 0.9 0.025 14.3 0.6 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF3593) Leu_zip PF15294.1 KEY74021.1 - 0.00099 18.2 0.7 0.0012 18.0 0.5 1.1 1 0 0 1 1 1 1 Leucine zipper Prefoldin PF02996.12 KEY74021.1 - 0.0041 16.7 3.2 0.11 12.1 0.3 2.2 1 1 0 2 2 2 1 Prefoldin subunit CCDC92 PF14916.1 KEY74021.1 - 0.0081 15.7 0.2 0.016 14.7 0.1 1.5 1 0 0 1 1 1 1 Coiled-coil domain of unknown function FlxA PF14282.1 KEY74021.1 - 0.012 15.4 0.5 0.019 14.8 0.4 1.4 1 1 0 1 1 1 0 FlxA-like protein Exonuc_VII_S PF02609.11 KEY74021.1 - 0.026 14.3 2.0 0.36 10.6 0.2 2.4 2 0 0 2 2 2 0 Exonuclease VII small subunit MAD PF05557.8 KEY74021.1 - 0.037 12.1 0.3 0.04 12.0 0.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein AKNA PF12443.3 KEY74021.1 - 0.044 13.8 1.0 0.07 13.1 0.2 1.7 1 1 1 2 2 2 0 AT-hook-containing transcription factor Takusan PF04822.8 KEY74021.1 - 0.061 13.0 0.9 2.6 7.8 0.1 2.2 2 0 0 2 2 2 0 Takusan DivIC PF04977.10 KEY74021.1 - 0.062 12.7 1.3 0.099 12.1 0.3 1.7 2 0 0 2 2 2 0 Septum formation initiator DUF1192 PF06698.6 KEY74021.1 - 0.097 12.4 0.5 0.16 11.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Rab5-bind PF09311.6 KEY74021.1 - 0.14 12.0 4.6 0.22 11.3 3.2 1.4 1 1 0 1 1 1 0 Rabaptin-like protein Cep57_MT_bd PF06657.8 KEY74021.1 - 0.17 11.8 1.3 0.56 10.1 0.1 2.1 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Tropomyosin_1 PF12718.2 KEY74021.1 - 0.46 10.3 4.2 1.2 8.9 2.9 1.7 1 1 0 1 1 1 0 Tropomyosin like CAF-1_p150 PF11600.3 KEY74022.1 - 0.0055 16.1 6.5 0.0055 16.1 4.5 4.6 4 1 1 5 5 5 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1525 PF07511.6 KEY74022.1 - 0.061 13.3 0.1 0.19 11.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) PAF-AH_p_II PF03403.8 KEY74023.1 - 1.2e-45 155.4 0.0 3.2e-22 78.3 0.0 3.1 3 0 0 3 3 3 3 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KEY74023.1 - 6.2e-12 45.4 0.0 3.1e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY74023.1 - 2.8e-08 33.9 0.3 1.1e-07 32.0 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KEY74023.1 - 7.5e-06 25.0 0.0 0.00032 19.6 0.0 2.2 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KEY74023.1 - 5.2e-05 22.1 0.0 0.00047 19.0 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.3 KEY74023.1 - 0.022 14.6 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Ribosomal_S30 PF04758.9 KEY74024.1 - 5.8e-29 99.6 4.3 7e-29 99.3 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 RRM_1 PF00076.17 KEY74025.1 - 2.5e-15 55.8 0.0 3.8e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY74025.1 - 5.4e-13 48.7 0.0 8e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY74025.1 - 1.1e-10 41.1 0.0 1.7e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KEY74025.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif Glyco_hydro_3 PF00933.16 KEY74026.1 - 2.4e-84 282.8 0.0 3.4e-84 282.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY74026.1 - 4.9e-67 225.7 0.3 3.3e-65 219.8 0.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEY74026.1 - 9.1e-22 76.7 0.0 1.9e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KEY74026.1 - 3.6e-20 72.1 0.0 6.3e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Calcipressin PF04847.7 KEY74026.1 - 0.33 10.5 0.9 0.69 9.4 0.6 1.5 1 0 0 1 1 1 0 Calcipressin NUDIX PF00293.23 KEY74028.1 - 1e-21 77.0 0.1 1.2e-21 76.7 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain zf-C2HC_2 PF13913.1 KEY74029.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type LRR_1 PF00560.28 KEY74029.1 - 0.19 11.8 11.0 1.1e+02 3.4 0.1 6.4 5 0 0 5 5 5 0 Leucine Rich Repeat Atg14 PF10186.4 KEY74030.1 - 7.4e-19 67.8 0.7 1.4e-18 66.8 0.5 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 ATLF PF07737.6 KEY74030.1 - 0.028 13.8 0.2 0.87 8.9 0.0 2.1 2 0 0 2 2 2 0 Anthrax toxin lethal factor, N- and C-terminal domain DegT_DnrJ_EryC1 PF01041.12 KEY74030.1 - 0.25 10.3 4.1 0.41 9.6 2.9 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Sec8_exocyst PF04048.9 KEY74030.1 - 0.27 10.8 5.7 0.29 10.7 2.8 1.7 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Borrelia_P83 PF05262.6 KEY74030.1 - 0.37 9.0 7.6 0.69 8.1 5.3 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein APG6 PF04111.7 KEY74030.1 - 0.42 9.6 7.3 2.2 7.2 5.1 2.0 1 1 0 1 1 1 0 Autophagy protein Apg6 Fib_alpha PF08702.5 KEY74030.1 - 8.6 6.4 8.7 17 5.4 6.0 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc7 PF08317.6 KEY74030.1 - 8.9 4.8 11.2 16 4.0 7.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein WD40 PF00400.27 KEY74031.1 - 2.1e-14 52.7 8.3 5.3e-08 32.4 0.6 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF1183 PF06682.7 KEY74032.1 - 0.014 15.0 5.5 0.017 14.7 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) zf-MYND PF01753.13 KEY74033.1 - 0.2 11.5 3.6 0.36 10.7 2.5 1.4 1 0 0 1 1 1 0 MYND finger zf-B_box PF00643.19 KEY74033.1 - 0.21 11.4 3.2 0.35 10.7 2.2 1.3 1 0 0 1 1 1 0 B-box zinc finger LMBR1 PF04791.11 KEY74034.1 - 3e-17 62.3 1.5 3e-17 62.3 1.0 2.3 1 1 1 2 2 2 2 LMBR1-like membrane protein DUF1980 PF09323.5 KEY74034.1 - 1.3 8.6 4.3 14 5.3 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) CPSF_A PF03178.10 KEY74035.1 - 1.1e-72 244.8 0.0 2.6e-72 243.6 0.0 1.7 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 KEY74035.1 - 0.086 10.9 0.1 0.2 9.7 0.0 1.6 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Pal1 PF08316.6 KEY74036.1 - 8e-10 39.3 0.1 2.4e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Pal1 cell morphology protein DUF2360 PF10152.4 KEY74036.1 - 7.7 6.7 7.3 19 5.5 4.7 2.0 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) HVSL PF09749.4 KEY74037.1 - 2.9e-63 213.0 0.2 3.5e-63 212.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.1 KEY74037.1 - 0.0031 17.2 0.0 0.0078 15.9 0.0 1.7 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily TGFb_propeptide PF00688.13 KEY74037.1 - 0.033 13.4 0.0 0.078 12.2 0.0 1.6 2 0 0 2 2 2 0 TGF-beta propeptide CKS PF01111.14 KEY74038.1 - 6.2e-36 122.0 0.8 7.5e-36 121.7 0.6 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit ERO1 PF04137.10 KEY74039.1 - 7.8e-139 462.6 0.0 7.8e-139 462.6 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Sugar_tr PF00083.19 KEY74042.1 - 7.6e-127 423.6 19.6 8.7e-127 423.4 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY74042.1 - 1.1e-19 70.3 48.3 2.4e-18 66.0 17.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_transf_64 PF09258.5 KEY74044.1 - 2.1e-57 194.1 0.0 2.5e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glycos_transf_2 PF00535.21 KEY74044.1 - 0.0031 17.2 0.2 0.036 13.7 0.2 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 2 FAD_binding_2 PF00890.19 KEY74045.1 - 5.4e-85 285.7 0.6 6.7e-85 285.4 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 KEY74045.1 - 2.6e-21 75.1 0.2 1.8e-19 69.3 0.0 3.1 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 KEY74045.1 - 2e-13 49.9 0.6 6e-13 48.4 0.4 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KEY74045.1 - 3.7e-09 36.1 0.1 1.1e-08 34.5 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEY74045.1 - 2.1e-08 34.2 0.0 1e-06 28.7 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY74045.1 - 5.6e-08 32.7 2.7 1.7e-07 31.1 0.3 2.8 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KEY74045.1 - 3.8e-06 26.1 0.5 0.0026 16.8 0.1 3.0 3 0 0 3 3 3 2 Thi4 family HI0933_like PF03486.9 KEY74045.1 - 1.1e-05 24.1 1.6 0.0049 15.3 0.1 3.4 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.14 KEY74045.1 - 0.00032 19.8 1.2 0.0079 15.2 0.6 2.1 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 KEY74045.1 - 0.0024 16.8 1.5 0.098 11.4 0.6 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Amino_oxidase PF01593.19 KEY74045.1 - 0.0031 16.6 0.3 0.25 10.3 0.1 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KEY74045.1 - 0.035 14.1 0.1 0.079 13.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY74045.1 - 0.87 10.0 4.5 3.8 7.9 1.3 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fasciclin PF02469.17 KEY74046.1 - 0.00069 19.6 0.0 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 Fasciclin domain SRF-TF PF00319.13 KEY74047.1 - 1.5e-21 75.3 0.1 2.3e-21 74.7 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3591 PF12157.3 KEY74048.1 - 2.4e-178 593.2 1.8 2.4e-178 593.2 1.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) Raffinose_syn PF05691.7 KEY74048.1 - 0.028 11.9 0.2 0.043 11.3 0.1 1.2 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 GFO_IDH_MocA PF01408.17 KEY74049.1 - 4.1e-15 56.3 0.0 7.3e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CENP-L PF13092.1 KEY74050.1 - 9.1e-48 162.1 0.0 1.8e-45 154.6 0.0 2.1 2 0 0 2 2 2 2 Kinetochore complex Sim4 subunit Fta1 ADH_zinc_N PF00107.21 KEY74051.1 - 1.2e-24 86.2 0.3 2.4e-24 85.3 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY74051.1 - 3.7e-11 43.9 0.1 1.1e-10 42.5 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY74051.1 - 6.8e-11 41.8 0.5 1.5e-10 40.8 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Metallophos_2 PF12850.2 KEY74051.1 - 3.1e-10 40.1 0.3 6.2e-10 39.1 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KEY74051.1 - 3.1e-08 33.2 0.2 5.2e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AlaDh_PNT_C PF01262.16 KEY74051.1 - 0.014 14.9 0.2 0.042 13.4 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 KEY74051.1 - 0.019 14.9 0.0 0.075 13.0 0.0 2.0 1 0 0 1 1 1 0 TrkA-N domain ArsA_ATPase PF02374.10 KEY74051.1 - 0.036 13.1 0.3 0.072 12.1 0.2 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase DAO PF01266.19 KEY74052.1 - 2.2e-43 148.5 0.5 3e-43 148.1 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEY74052.1 - 2.1e-06 27.9 0.5 0.0044 17.1 0.1 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY74052.1 - 3.7e-05 23.6 0.1 0.00011 22.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEY74052.1 - 0.00045 19.1 0.2 0.4 9.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 KEY74052.1 - 0.0014 18.4 0.1 0.043 13.5 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 KEY74052.1 - 0.0096 15.0 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 KEY74052.1 - 0.018 13.9 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEY74052.1 - 0.066 13.0 0.0 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cupin_1 PF00190.17 KEY74053.1 - 2.4e-10 39.9 0.1 4.3e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 KEY74053.1 - 0.0023 17.4 0.0 0.0039 16.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain ADH_zinc_N PF00107.21 KEY74055.1 - 6.4e-12 45.1 0.0 1.2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY74055.1 - 5.7e-08 32.4 0.2 1.6e-07 31.0 0.0 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Acetyltransf_1 PF00583.19 KEY74056.1 - 2.5e-14 53.0 0.0 4.8e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KEY74056.1 - 5e-08 32.6 0.0 8.2e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KEY74056.1 - 8.3e-07 29.0 0.0 1.3e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEY74056.1 - 0.00045 20.3 0.0 0.00062 19.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KEY74056.1 - 0.001 19.2 0.0 0.0022 18.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KEY74056.1 - 0.039 13.8 0.0 0.84 9.5 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KEY74056.1 - 0.04 13.5 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Strep_SA_rep PF06696.6 KEY74056.1 - 0.12 12.1 0.1 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Streptococcal surface antigen repeat Complex1_LYR PF05347.10 KEY74057.1 - 5.3e-05 22.9 2.0 5.3e-05 22.9 1.4 3.2 3 0 0 3 3 3 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KEY74057.1 - 0.0001 22.4 9.1 0.0011 19.1 3.0 3.5 2 1 0 2 2 2 1 Complex1_LYR-like Ank_4 PF13637.1 KEY74058.1 - 6.3e-15 55.2 0.4 1.1e-08 35.3 0.1 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEY74058.1 - 3.6e-14 52.8 1.2 1.1e-05 25.6 0.1 3.9 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEY74058.1 - 1.5e-12 46.6 1.9 8.1e-05 22.2 0.0 4.5 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 KEY74058.1 - 4.6e-12 44.9 0.3 0.00097 19.1 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KEY74058.1 - 1.9e-09 37.4 0.3 0.0032 17.6 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.8 KEY74058.1 - 2.8e-05 23.6 0.2 8.7e-05 22.1 0.1 1.9 1 1 0 1 1 1 1 KilA-N domain Macoilin PF09726.4 KEY74058.1 - 0.00086 17.7 1.3 0.00086 17.7 0.9 1.4 2 0 0 2 2 2 1 Transmembrane protein Filament PF00038.16 KEY74058.1 - 0.011 15.2 6.8 0.022 14.2 4.7 1.4 1 0 0 1 1 1 0 Intermediate filament protein OmpH PF03938.9 KEY74058.1 - 0.025 14.5 9.5 0.061 13.2 6.6 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.10 KEY74058.1 - 0.16 11.1 7.8 0.28 10.3 5.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_GP20 PF06810.6 KEY74058.1 - 0.16 11.3 6.9 0.32 10.4 4.8 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 Hrs_helical PF12210.3 KEY74058.1 - 0.3 11.3 6.5 0.32 11.2 2.7 2.4 3 0 0 3 3 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate IncA PF04156.9 KEY74058.1 - 0.36 10.3 7.9 0.66 9.5 5.5 1.4 1 0 0 1 1 1 0 IncA protein ALMT PF11744.3 KEY74058.1 - 1.2 7.6 2.8 1.8 7.0 1.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Cluap1 PF10234.4 KEY74058.1 - 1.3 8.2 8.9 0.48 9.5 4.0 1.7 2 0 0 2 2 2 0 Clusterin-associated protein-1 Spc7 PF08317.6 KEY74058.1 - 1.6 7.2 9.6 0.38 9.3 4.4 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein APG6 PF04111.7 KEY74058.1 - 1.9 7.4 8.4 3.6 6.5 5.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 FYVE PF01363.16 KEY74059.1 - 1.7e-23 82.2 22.1 1.3e-16 60.2 6.0 3.0 3 0 0 3 3 3 2 FYVE zinc finger zf-Di19 PF05605.7 KEY74059.1 - 7.4e-05 22.7 5.7 0.009 16.1 0.0 2.7 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.11 KEY74059.1 - 0.00061 19.5 2.5 0.00061 19.5 1.7 4.0 4 1 1 5 5 4 1 AN1-like Zinc finger Rbsn PF11464.3 KEY74059.1 - 0.0024 17.4 1.2 0.0071 15.8 0.2 2.3 2 0 0 2 2 2 1 Rabenosyn Rab binding domain PhnA_Zn_Ribbon PF08274.7 KEY74059.1 - 0.0057 16.4 0.4 25 4.7 0.1 4.3 4 1 0 4 4 4 0 PhnA Zinc-Ribbon DUF3719 PF12516.3 KEY74059.1 - 0.035 13.6 0.9 0.14 11.7 0.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) HypA PF01155.14 KEY74059.1 - 0.91 9.2 9.6 0.29 10.8 0.3 3.4 4 0 0 4 4 4 0 Hydrogenase expression/synthesis hypA family TMF_DNA_bd PF12329.3 KEY74059.1 - 0.95 9.3 11.0 3.1 7.6 0.6 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 KEY74059.1 - 3.4 6.0 4.5 7.2 4.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain zf-DHHC PF01529.15 KEY74059.1 - 6.1 6.2 8.3 0.19 11.0 0.5 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase zf-C2HC5 PF06221.8 KEY74059.1 - 6.2 6.6 22.1 1.1 9.0 0.8 4.3 4 1 1 5 5 5 0 Putative zinc finger motif, C2HC5-type zf-RING_3 PF14369.1 KEY74059.1 - 7.5 6.6 10.9 5.2 7.1 0.1 4.0 4 0 0 4 4 4 0 zinc-finger DUF393 PF04134.7 KEY74059.1 - 8.8 7.4 6.9 20 6.3 0.5 3.2 3 1 0 3 3 2 0 Protein of unknown function, DUF393 NAD_binding_7 PF13241.1 KEY74060.1 - 3.3e-31 107.5 0.1 5.7e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KEY74060.1 - 5.7e-26 89.6 0.0 9.5e-26 88.9 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KEY74060.1 - 4.7e-15 54.2 0.2 8.8e-15 53.3 0.2 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central TrkA_N PF02254.13 KEY74060.1 - 0.0073 16.2 0.2 0.014 15.4 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.12 KEY74060.1 - 0.059 13.7 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 KEY74060.1 - 0.22 11.3 0.9 0.52 10.1 0.0 1.9 1 1 0 2 2 2 0 ThiF family A_deaminase PF00962.17 KEY74061.1 - 2e-30 105.8 0.0 4.4e-24 84.9 0.0 2.0 2 0 0 2 2 2 2 Adenosine/AMP deaminase Peptidase_M14 PF00246.19 KEY74062.1 - 1.6e-67 228.0 0.0 2.1e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase MFS_1 PF07690.11 KEY74064.1 - 1.6e-35 122.4 29.1 1.6e-35 122.4 20.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Amidoligase_2 PF12224.3 KEY74065.1 - 2.6e-10 40.3 0.1 9.7e-09 35.2 0.1 2.2 1 1 0 1 1 1 1 Putative amidoligase enzyme Glyco_hydro_18 PF00704.23 KEY74069.1 - 7.9e-78 262.2 0.0 1.1e-77 261.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KEY74069.1 - 2.7e-10 40.0 15.5 2.7e-10 40.0 10.8 5.4 5 0 0 5 5 5 2 Chitin recognition protein LysM PF01476.15 KEY74070.1 - 5.1e-18 64.6 0.1 0.00042 20.1 0.0 5.2 5 0 0 5 5 5 4 LysM domain NACHT PF05729.7 KEY74072.1 - 4.3e-09 36.2 0.0 1.1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Ank_2 PF12796.2 KEY74072.1 - 8.1e-09 35.7 0.2 7.4e-05 23.0 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEY74072.1 - 1.2e-06 28.0 0.1 0.00057 19.5 0.0 4.2 3 1 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 KEY74072.1 - 0.00026 20.9 0.8 0.047 13.9 0.0 4.8 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.1 KEY74072.1 - 0.0018 18.7 0.4 0.3 11.6 0.0 4.1 4 1 1 5 5 5 2 Ankyrin repeats (many copies) NB-ARC PF00931.17 KEY74072.1 - 0.016 14.1 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Ank_5 PF13857.1 KEY74072.1 - 0.054 13.7 0.1 2.9 8.2 0.0 3.4 4 0 0 4 4 4 0 Ankyrin repeats (many copies) AAA_22 PF13401.1 KEY74072.1 - 0.073 13.2 0.2 0.21 11.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 KEY74073.1 - 2.2e-54 184.2 0.0 1.6e-38 132.2 0.0 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain Rubredoxin PF00301.15 KEY74073.1 - 1.3 8.9 4.8 8.4 6.3 1.8 2.8 2 1 0 2 2 2 0 Rubredoxin DUF1272 PF06906.6 KEY74073.1 - 3.5 7.5 6.6 6 6.8 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) OrfB_Zn_ribbon PF07282.6 KEY74073.1 - 5 6.8 6.2 24 4.6 1.0 2.7 1 1 1 2 2 2 0 Putative transposase DNA-binding domain MFS_1 PF07690.11 KEY74074.1 - 1.4e-33 116.0 27.0 1.6e-33 115.8 18.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3723 PF12520.3 KEY74077.1 - 1.9e-54 185.0 4.1 7.7e-54 183.0 1.5 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3723) Med9 PF07544.8 KEY74078.1 - 0.0087 15.7 3.7 0.018 14.7 2.6 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Microtub_assoc PF07989.6 KEY74078.1 - 0.018 14.8 1.7 0.035 13.9 1.2 1.5 1 0 0 1 1 1 0 Microtubule associated KLRAQ PF10205.4 KEY74078.1 - 0.019 15.0 4.8 0.019 15.0 3.3 1.8 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein IncA PF04156.9 KEY74078.1 - 0.026 14.1 9.7 0.032 13.8 6.7 1.1 1 0 0 1 1 1 0 IncA protein ApoLp-III PF07464.6 KEY74078.1 - 0.054 13.5 6.2 0.072 13.1 4.3 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF3573 PF12097.3 KEY74078.1 - 0.17 10.4 1.8 0.2 10.2 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Tropomyosin_1 PF12718.2 KEY74078.1 - 0.19 11.5 11.3 0.051 13.4 5.6 1.5 1 1 0 1 1 1 0 Tropomyosin like Atg14 PF10186.4 KEY74078.1 - 0.33 9.8 9.8 0.41 9.5 6.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CHD5 PF04420.9 KEY74078.1 - 0.33 10.5 1.8 0.42 10.2 1.0 1.4 1 1 0 1 1 1 0 CHD5-like protein TMF_DNA_bd PF12329.3 KEY74078.1 - 0.35 10.6 9.1 0.11 12.2 4.4 1.6 2 0 0 2 2 1 0 TATA element modulatory factor 1 DNA binding NuA4 PF09340.5 KEY74078.1 - 0.47 10.1 2.9 3.2 7.4 2.0 2.1 1 1 0 1 1 1 0 Histone acetyltransferase subunit NuA4 OmpH PF03938.9 KEY74078.1 - 0.48 10.3 9.2 0.66 9.9 6.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) NABP PF07990.7 KEY74078.1 - 0.59 9.3 3.5 0.69 9.1 2.4 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Mt_ATP-synt_B PF05405.9 KEY74078.1 - 0.74 9.2 6.8 1 8.8 4.7 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Mnd1 PF03962.10 KEY74078.1 - 0.94 9.1 9.6 1.2 8.7 6.7 1.1 1 0 0 1 1 1 0 Mnd1 family ADIP PF11559.3 KEY74078.1 - 1.4 8.8 15.1 0.72 9.7 9.0 1.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding PFEMP PF03011.10 KEY74078.1 - 1.8 8.9 7.4 0.16 12.3 2.2 1.5 2 0 0 2 2 1 0 PFEMP DBL domain DivIC PF04977.10 KEY74078.1 - 1.9 8.0 5.7 4 6.9 4.0 1.5 1 0 0 1 1 1 0 Septum formation initiator Macoilin PF09726.4 KEY74078.1 - 3.1 5.9 11.1 3.6 5.7 7.7 1.0 1 0 0 1 1 1 0 Transmembrane protein APG6 PF04111.7 KEY74078.1 - 4.1 6.3 10.9 5.2 6.0 7.4 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 Siah-Interact_N PF09032.6 KEY74078.1 - 4.7 7.3 10.4 2.4 8.2 5.4 1.8 1 1 1 2 2 2 0 Siah interacting protein, N terminal DUF972 PF06156.8 KEY74078.1 - 9.5 6.6 8.9 2.9 8.2 3.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF2046 PF09755.4 KEY74080.1 - 0.01 14.7 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) TMF_TATA_bd PF12325.3 KEY74080.1 - 0.046 13.4 2.5 0.17 11.5 1.7 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DASH_Dad3 PF08656.5 KEY74080.1 - 0.083 12.5 0.7 0.46 10.2 0.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad3 zf-C2H2 PF00096.21 KEY74084.1 - 9.1e-06 25.7 21.2 0.0013 18.9 0.3 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY74084.1 - 0.024 14.9 0.3 0.024 14.9 0.2 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger DUF202 PF02656.10 KEY74085.1 - 0.0019 18.3 4.4 0.0028 17.8 1.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Zn_clus PF00172.13 KEY74086.1 - 1.9e-07 30.8 8.4 3.1e-07 30.2 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 KEY74087.1 - 3.9e-24 85.8 1.7 6.2e-24 85.1 1.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY74087.1 - 5.5e-11 42.4 2.1 7.4e-11 41.9 0.1 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family CFEM PF05730.6 KEY74087.1 - 1.5e-09 37.5 11.4 1.5e-09 37.5 7.9 1.6 2 0 0 2 2 2 1 CFEM domain Thioesterase PF00975.15 KEY74087.1 - 0.00025 21.3 0.0 0.00049 20.3 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 KEY74087.1 - 0.00027 20.5 0.0 0.004 16.7 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 KEY74087.1 - 0.0033 17.2 0.0 0.067 13.0 0.0 2.5 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.3 KEY74087.1 - 0.025 14.4 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Lipase_3 PF01764.20 KEY74087.1 - 0.057 13.0 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 KEY74087.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ribul_P_3_epim PF00834.14 KEY74088.1 - 8e-63 211.1 0.0 3.6e-62 209.0 0.0 1.8 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 KEY74088.1 - 0.014 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.19 KEY74088.1 - 0.026 13.9 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.9 KEY74088.1 - 0.029 13.4 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG PcrB PF01884.12 KEY74088.1 - 0.12 11.6 0.1 0.19 10.9 0.0 1.4 1 1 0 1 1 1 0 PcrB family PG_binding_3 PF09374.5 KEY74088.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Predicted Peptidoglycan domain Ofd1_CTDD PF10637.4 KEY74089.1 - 6e-103 343.6 0.0 1.9e-94 315.7 0.0 2.1 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 KEY74089.1 - 1.1e-15 57.9 0.0 2.7e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KEY74089.1 - 0.04 13.5 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily CUE PF02845.11 KEY74091.1 - 9.6e-08 31.3 0.0 1.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 CUE domain MFS_1 PF07690.11 KEY74092.1 - 1.7e-40 138.8 57.4 4.2e-30 104.6 16.1 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily PepSY_TM_2 PF13703.1 KEY74092.1 - 0.014 15.5 2.4 0.014 15.5 1.7 4.0 4 1 1 5 5 5 0 PepSY-associated TM helix E1-E2_ATPase PF00122.15 KEY74093.1 - 7.6e-16 57.8 0.0 1.4e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KEY74093.1 - 1.6e-15 58.1 0.1 5.3e-11 43.3 0.0 3.4 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEY74093.1 - 4.6e-13 49.7 0.0 7e-12 45.9 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEY74093.1 - 9.6e-10 38.2 0.0 3.3e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEY74093.1 - 0.016 14.7 0.1 0.07 12.7 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KEY74093.1 - 0.11 12.4 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase TFIIB PF00382.14 KEY74094.1 - 8.4e-33 112.0 0.2 4.3e-19 68.0 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 KEY74094.1 - 5.9e-12 44.7 4.5 1e-11 43.9 3.1 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 KEY74094.1 - 0.003 17.4 0.0 1.7 8.6 0.0 2.6 1 1 2 3 3 3 2 Cyclin, C-terminal domain HTH_Tnp_ISL3 PF13542.1 KEY74094.1 - 0.017 14.3 0.0 0.73 9.0 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Cyclin_N PF00134.18 KEY74094.1 - 0.021 14.4 0.3 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 Cyclin, N-terminal domain RB_B PF01857.15 KEY74094.1 - 0.025 14.0 0.2 0.046 13.2 0.2 1.6 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain Trm112p PF03966.11 KEY74094.1 - 0.045 14.1 0.3 0.18 12.1 0.2 2.3 1 1 0 1 1 1 0 Trm112p-like protein Glycos_transf_3 PF00591.16 KEY74095.1 - 2.5e-61 207.3 0.0 3.9e-61 206.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 KEY74095.1 - 8e-11 41.3 0.2 1.6e-10 40.4 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain CoA_transf_3 PF02515.12 KEY74097.1 - 4.2e-58 195.7 0.0 7e-58 195.0 0.0 1.4 1 0 0 1 1 1 1 CoA-transferase family III RESP18 PF14948.1 KEY74097.1 - 0.011 15.7 0.4 0.033 14.2 0.3 1.8 1 0 0 1 1 1 0 RESP18 domain DGC PF08859.6 KEY74098.1 - 0.027 14.3 0.7 0.069 13.0 0.5 1.6 1 0 0 1 1 1 0 DGC domain DUF2637 PF10935.3 KEY74100.1 - 0.021 14.7 4.2 0.037 13.9 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2637) NADH-u_ox-rdase PF10785.4 KEY74100.1 - 0.13 12.5 0.1 0.13 12.5 0.1 2.3 3 1 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF95 PF01944.12 KEY74100.1 - 0.16 11.6 3.4 4.3 6.9 0.2 2.2 2 0 0 2 2 2 0 Integral membrane protein DUF95 Asn_synthase PF00733.16 KEY74101.1 - 1.8e-54 184.9 0.0 2.3e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KEY74101.1 - 1.2e-07 31.4 0.0 5.8e-07 29.2 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KEY74101.1 - 0.0033 17.3 0.0 0.007 16.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain zf-C2H2 PF00096.21 KEY74102.1 - 0.01 16.1 2.3 0.01 16.1 1.6 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY74102.1 - 0.25 11.7 15.8 0.3 11.5 0.8 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger PMT PF02366.13 KEY74105.1 - 1.2e-79 267.2 16.6 2e-79 266.4 11.5 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KEY74105.1 - 5.2e-21 75.0 1.0 6.3e-20 71.5 0.2 2.1 1 1 1 2 2 2 2 MIR domain Fascin PF06268.8 KEY74105.1 - 0.13 12.3 0.0 0.82 9.7 0.0 2.1 2 0 0 2 2 2 0 Fascin domain Ribonuc_L-PSP PF01042.16 KEY74106.1 - 5.6e-40 135.8 0.0 6.3e-40 135.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP WD40 PF00400.27 KEY74107.1 - 4.2e-21 73.9 14.0 3.5e-08 33.0 0.0 5.7 5 1 0 5 5 5 4 WD domain, G-beta repeat Rax2 PF12768.2 KEY74107.1 - 0.006 15.8 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Gmad1 PF10647.4 KEY74107.1 - 0.058 12.7 0.6 2.6 7.3 0.0 2.5 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain RRM_5 PF13893.1 KEY74108.1 - 5e-10 39.0 0.0 7.7e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEY74108.1 - 3.2e-08 33.0 0.0 8.3e-08 31.7 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY74108.1 - 1.1e-05 25.3 0.0 2.7e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 KEY74108.1 - 0.00027 20.5 0.0 0.00044 19.8 0.0 1.3 1 0 0 1 1 1 1 Calcipressin Limkain-b1 PF11608.3 KEY74108.1 - 0.004 16.8 0.0 0.0094 15.6 0.0 1.6 1 0 0 1 1 1 1 Limkain b1 Autophagy_act_C PF03987.10 KEY74109.1 - 3.6e-13 49.4 0.0 7.8e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Glyco_hydro_47 PF01532.15 KEY74110.1 - 7.2e-163 542.4 0.0 8.6e-163 542.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AA_permease PF00324.16 KEY74111.1 - 2.8e-134 448.0 35.5 3.2e-134 447.8 24.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEY74111.1 - 2.6e-34 118.4 37.6 3.2e-34 118.2 26.1 1.1 1 0 0 1 1 1 1 Amino acid permease BNR_2 PF13088.1 KEY74113.1 - 2.6e-11 43.3 6.2 0.023 13.9 0.0 5.8 4 2 1 5 5 5 4 BNR repeat-like domain BNR PF02012.15 KEY74113.1 - 5.3e-09 34.5 49.2 0.39 10.7 0.3 11.6 11 0 0 11 11 11 7 BNR/Asp-box repeat DUF2561 PF10812.3 KEY74113.1 - 0.056 13.0 0.5 0.1 12.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Sensor PF13796.1 KEY74114.1 - 1.2 8.6 3.2 0.48 10.0 0.3 1.6 2 0 0 2 2 2 0 Putative sensor Med16 PF11635.3 KEY74115.1 - 3.7e-99 332.7 0.0 4e-58 197.0 0.0 2.0 1 1 1 2 2 2 2 Mediator complex subunit 16 Filament PF00038.16 KEY74116.1 - 0.0008 18.9 7.6 0.0008 18.9 5.3 6.7 5 2 1 6 6 6 2 Intermediate filament protein Macoilin PF09726.4 KEY74116.1 - 0.0013 17.1 9.9 0.0013 17.1 6.8 3.5 3 1 1 4 4 4 2 Transmembrane protein Reo_sigmaC PF04582.7 KEY74116.1 - 0.0022 17.2 24.4 0.033 13.3 1.4 4.6 5 0 0 5 5 5 3 Reovirus sigma C capsid protein PLAC9 PF15205.1 KEY74116.1 - 0.012 15.8 0.2 0.058 13.6 0.1 2.2 1 0 0 1 1 1 0 Placenta-specific protein 9 Ammonium_transp PF00909.16 KEY74117.1 - 4.6e-118 394.1 27.2 5.3e-118 393.9 18.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DNA_pol_B_palm PF14792.1 KEY74118.1 - 6.7e-35 119.5 0.0 1.2e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 KEY74118.1 - 1.4e-23 82.3 0.0 1.9e-22 78.6 0.1 2.4 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 KEY74118.1 - 9.8e-20 69.8 0.5 1.9e-19 68.9 0.4 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 KEY74118.1 - 4.8e-17 61.9 0.1 1.3e-16 60.5 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain Tim17 PF02466.14 KEY74119.1 - 1.3e-22 80.2 0.0 1.7e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PepSY_TM_2 PF13703.1 KEY74119.1 - 0.13 12.4 2.7 6.2 7.0 0.0 2.4 2 0 0 2 2 2 0 PepSY-associated TM helix PCI PF01399.22 KEY74120.1 - 2.8e-14 53.3 0.0 1.5e-13 50.9 0.0 2.2 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.4 KEY74120.1 - 0.01 15.2 0.4 0.023 14.1 0.0 1.8 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Lipase_GDSL_2 PF13472.1 KEY74121.1 - 2.4e-19 70.1 0.0 3.4e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KEY74121.1 - 9.3e-09 35.4 0.0 4.1e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Rad17 PF03215.10 KEY74122.1 - 3e-54 184.5 0.0 4.6e-54 183.9 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KEY74122.1 - 0.00053 20.1 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEY74122.1 - 0.00061 20.6 0.0 0.0015 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KEY74122.1 - 0.0011 19.1 0.0 0.0028 17.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEY74122.1 - 0.0017 18.0 0.1 0.0047 16.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 KEY74122.1 - 0.0021 18.3 0.0 0.005 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KEY74122.1 - 0.0034 16.9 0.0 0.0082 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEY74122.1 - 0.0055 16.5 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEY74122.1 - 0.0062 16.5 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 KEY74122.1 - 0.0079 15.1 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein NACHT PF05729.7 KEY74122.1 - 0.011 15.3 0.0 0.028 14.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.13 KEY74122.1 - 0.017 14.6 0.0 0.043 13.3 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 KEY74122.1 - 0.071 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 KEY74122.1 - 0.08 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KEY74122.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain ORC6 PF05460.8 KEY74122.1 - 9.5 5.2 10.9 26 3.7 7.6 1.8 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF4243 PF14027.1 KEY74123.1 - 5.8e-75 252.7 0.1 7.4e-75 252.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) HECT_2 PF09814.4 KEY74124.1 - 1.8e-57 194.6 0.2 2.6e-57 194.1 0.1 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding SNF2_N PF00176.18 KEY74124.1 - 4.8e-30 104.3 0.0 4.8e-28 97.8 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 KEY74124.1 - 0.0044 16.8 0.1 0.0099 15.7 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain F-box-like PF12937.2 KEY74126.1 - 0.0009 18.9 0.1 0.0036 16.9 0.0 2.1 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KEY74126.1 - 0.0016 18.0 14.2 0.21 11.2 0.3 4.1 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) F-box PF00646.28 KEY74126.1 - 0.059 13.0 3.1 0.28 10.8 0.2 2.9 2 1 0 2 2 2 0 F-box domain LRR_8 PF13855.1 KEY74126.1 - 0.88 9.3 10.3 4.1 7.2 0.3 3.2 1 1 1 2 2 2 0 Leucine rich repeat LRR_7 PF13504.1 KEY74126.1 - 7.8 7.1 9.7 13 6.5 0.2 4.4 5 0 0 5 5 5 0 Leucine rich repeat BTB PF00651.26 KEY74133.1 - 0.00025 21.0 0.0 0.00066 19.6 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Rootletin PF15035.1 KEY74134.1 - 0.036 14.0 0.2 0.059 13.3 0.1 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion zf-C2H2_4 PF13894.1 KEY74134.1 - 0.95 9.9 11.2 0.79 10.1 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Pkinase PF00069.20 KEY74136.1 - 1.1e-56 191.9 0.0 1.6e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY74136.1 - 2.1e-27 95.8 0.0 2.8e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY74136.1 - 0.0019 17.1 0.0 0.0035 16.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEY74136.1 - 0.052 12.6 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEY74136.1 - 0.078 12.6 0.2 0.93 9.1 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.17 KEY74136.1 - 0.11 11.8 0.0 0.27 10.5 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Neuroparsin PF07327.6 KEY74137.1 - 0.1 12.8 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Neuroparsin Pkinase PF00069.20 KEY74138.1 - 4.1e-59 199.8 0.0 1.1e-58 198.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY74138.1 - 5.1e-33 114.2 0.0 4.5e-31 107.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEY74138.1 - 5.4e-09 35.4 0.0 2.5e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KEY74138.1 - 0.00031 20.5 0.1 0.0019 18.0 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family TYA PF01021.14 KEY74138.1 - 2.7 8.2 5.3 2.7 8.2 0.0 2.4 2 0 0 2 2 2 0 TYA transposon protein Sybindin PF04099.7 KEY74139.1 - 1.6e-24 86.2 0.0 1.9e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KEY74139.1 - 0.036 13.9 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Peroxin-3 PF04882.7 KEY74140.1 - 6.8e-143 476.4 0.0 7.8e-143 476.2 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 DUF1649 PF07855.7 KEY74141.1 - 8.2e-56 188.1 0.0 1e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) ANAPC15 PF15243.1 KEY74141.1 - 0.081 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Fork_head PF00250.13 KEY74142.1 - 1.1e-33 115.0 0.3 1.9e-33 114.3 0.2 1.3 1 0 0 1 1 1 1 Fork head domain EF-hand_4 PF12763.2 KEY74143.1 - 3.7e-24 84.4 0.0 7.4e-13 48.1 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 KEY74143.1 - 0.00064 19.8 0.0 0.064 13.4 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair DUF1720 PF08226.6 KEY74143.1 - 0.0095 15.9 27.0 0.0095 15.9 18.7 7.0 6 2 2 8 8 8 3 Domain of unknown function (DUF1720) EF-hand_6 PF13405.1 KEY74143.1 - 0.077 12.9 0.3 6 7.0 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain LRR_6 PF13516.1 KEY74144.1 - 0.0085 16.0 0.1 0.0085 16.0 0.1 5.8 7 0 0 7 7 7 1 Leucine Rich repeat LRR_4 PF12799.2 KEY74144.1 - 0.028 14.0 11.1 2.3 7.9 0.3 5.5 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KEY74144.1 - 3.4 8.2 13.0 8.3 7.1 0.2 6.5 7 1 0 7 7 7 0 Leucine rich repeat NAD_binding_1 PF00175.16 KEY74145.1 - 7.6e-28 97.2 0.0 1.2e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KEY74145.1 - 1.2e-25 89.5 0.0 1.8e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KEY74145.1 - 6.2e-05 22.9 0.0 0.0029 17.5 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KEY74145.1 - 0.075 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain TPR_11 PF13414.1 KEY74146.1 - 4.5e-32 109.4 39.1 2e-10 40.1 0.9 11.7 8 4 7 15 15 15 7 TPR repeat TPR_1 PF00515.23 KEY74146.1 - 1.3e-27 94.1 27.8 3.4e-06 26.4 0.2 11.6 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_2 PF07719.12 KEY74146.1 - 2.6e-25 86.2 33.6 0.00015 21.4 0.2 12.3 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_12 PF13424.1 KEY74146.1 - 3e-22 78.3 29.6 1.4e-07 31.3 1.3 9.9 7 4 2 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 KEY74146.1 - 1.5e-21 74.4 21.8 2.3e-06 26.9 0.2 10.4 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 KEY74146.1 - 1.7e-20 71.6 33.0 0.00058 20.2 0.1 13.4 11 3 3 14 14 13 5 Tetratricopeptide repeat TPR_19 PF14559.1 KEY74146.1 - 4.7e-18 65.2 29.8 1.4e-05 25.3 0.1 10.5 9 2 2 11 11 11 6 Tetratricopeptide repeat TPR_7 PF13176.1 KEY74146.1 - 1.4e-14 52.6 24.7 0.00098 18.7 0.1 10.6 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_16 PF13432.1 KEY74146.1 - 5.6e-11 42.8 46.0 0.021 15.4 0.5 11.7 11 3 4 15 15 14 5 Tetratricopeptide repeat TPR_6 PF13174.1 KEY74146.1 - 1e-10 41.3 20.8 0.15 12.5 0.0 10.9 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEY74146.1 - 1.5e-10 40.4 13.2 0.22 11.7 0.1 11.0 10 1 1 11 11 11 2 Tetratricopeptide repeat Apc3 PF12895.2 KEY74146.1 - 6.5e-09 35.8 19.6 0.00015 21.8 1.8 7.1 7 1 0 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KEY74146.1 - 2.8e-05 23.8 18.8 2.3 8.2 0.0 9.7 10 0 0 10 10 10 2 Tetratricopeptide repeat Phage_integ_N PF09003.5 KEY74147.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage lambda integrase, N-terminal domain PX PF00787.19 KEY74148.1 - 1.7e-18 66.4 0.0 7.3e-18 64.4 0.0 2.1 3 0 0 3 3 3 1 PX domain Vps5 PF09325.5 KEY74148.1 - 2.1e-13 50.1 9.2 1.5e-07 30.9 0.1 2.2 2 0 0 2 2 2 2 Vps5 C terminal like mRNA_cap_enzyme PF01331.14 KEY74149.1 - 1.4e-51 174.9 0.2 1.9e-51 174.5 0.2 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 KEY74149.1 - 4.6e-23 81.5 0.6 9.3e-23 80.5 0.4 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 KEY74149.1 - 9.7e-07 28.3 0.1 2.8e-05 23.5 0.1 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Vip3A_N PF12495.3 KEY74149.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal HEAT_2 PF13646.1 KEY74151.1 - 2.7e-06 27.5 1.1 0.055 13.7 0.0 5.1 5 1 1 6 6 6 3 HEAT repeats HEAT PF02985.17 KEY74151.1 - 0.0073 16.2 2.3 2 8.7 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat DUF3511 PF12023.3 KEY74151.1 - 0.01 15.1 0.1 0.032 13.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3511) PNGaseA PF12222.3 KEY74151.1 - 0.31 9.8 0.0 0.49 9.1 0.0 1.2 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A SNF5 PF04855.7 KEY74152.1 - 9.1e-75 251.2 0.1 1.5e-74 250.5 0.1 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 TolB_N PF04052.8 KEY74152.1 - 0.078 13.0 0.0 0.59 10.2 0.0 2.2 2 1 0 2 2 2 0 TolB amino-terminal domain Peptidase_M24 PF00557.19 KEY74153.1 - 5.2e-10 39.2 0.0 6.6e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 PHD PF00628.24 KEY74154.1 - 3.4e-14 52.2 19.0 1.7e-09 37.2 7.0 2.5 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.17 KEY74154.1 - 0.00098 18.8 8.5 0.1 12.3 1.4 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_2 PF12674.2 KEY74154.1 - 0.072 13.4 0.7 0.2 12.0 0.5 1.7 1 0 0 1 1 1 0 Putative zinc ribbon domain Prok-RING_1 PF14446.1 KEY74154.1 - 0.21 11.3 16.2 1.8 8.3 4.3 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KEY74154.1 - 0.33 10.2 11.1 3 7.2 3.4 2.7 2 0 0 2 2 2 0 PHD-finger zf-PHD-like PF15446.1 KEY74154.1 - 2.3 7.4 8.1 3.3 6.9 1.9 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PUF PF00806.14 KEY74155.1 - 6.2e-26 88.3 0.0 3.4e-05 23.0 0.0 5.5 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 KEY74155.1 - 1.3e-12 47.1 0.0 2.6e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY74155.1 - 2.6e-06 27.1 0.0 5.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY74155.1 - 1.7e-05 24.7 0.0 6e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 KEY74156.1 - 6.8e-70 235.1 0.1 1.3e-69 234.2 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY74156.1 - 4.3e-53 180.0 0.1 7.5e-53 179.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KEY74156.1 - 2.6e-22 78.9 1.1 9e-22 77.2 0.0 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 KEY74156.1 - 6.6e-07 28.5 0.0 1.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 KEY74156.1 - 4.3e-06 26.9 0.1 1.8e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain APH PF01636.18 KEY74156.1 - 0.0089 15.7 4.7 0.014 15.1 0.1 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEY74156.1 - 0.03 13.1 0.1 0.049 12.4 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 tRNA-synt_2b PF00587.20 KEY74157.1 - 8.2e-68 227.3 0.1 1.4e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KEY74157.1 - 4.2e-22 77.8 0.2 2.8e-21 75.2 0.0 2.5 3 0 0 3 3 3 1 Anticodon binding domain AA_kinase PF00696.23 KEY74158.1 - 8e-38 130.3 2.4 1.2e-37 129.8 1.7 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 KEY74158.1 - 7e-15 54.5 1.0 1.9e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 PUA domain Peptidase_M76 PF09768.4 KEY74159.1 - 6.3e-68 227.6 1.1 8.3e-68 227.2 0.7 1.1 1 0 0 1 1 1 1 Peptidase M76 family Dicty_spore_N PF04562.7 KEY74159.1 - 0.14 12.4 1.8 1.6 9.0 0.2 2.4 2 1 1 3 3 3 0 Dictyostelium spore coat protein, N terminus SprT-like PF10263.4 KEY74159.1 - 1.9 8.1 11.8 0.032 13.9 2.1 2.3 2 2 0 2 2 2 0 SprT-like family Pkinase PF00069.20 KEY74160.1 - 7.9e-68 228.4 0.0 1e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY74160.1 - 6.2e-42 143.4 0.0 8.8e-42 142.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY74160.1 - 6.7e-06 25.2 0.0 1.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEY74160.1 - 0.0016 17.5 0.1 0.0028 16.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KEY74160.1 - 0.016 14.5 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 KEY74160.1 - 0.046 13.4 0.1 0.092 12.4 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family TIP41 PF04176.8 KEY74161.1 - 1.2e-73 246.2 0.4 1.5e-73 245.9 0.2 1.1 1 0 0 1 1 1 1 TIP41-like family DEAD PF00270.24 KEY74163.1 - 3.9e-31 107.8 0.0 8.2e-31 106.7 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY74163.1 - 7e-16 57.8 0.0 1.7e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEY74163.1 - 5.2e-06 26.4 0.0 0.00011 22.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KEY74163.1 - 0.00087 18.1 0.0 0.0015 17.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Docking PF08990.6 KEY74163.1 - 0.025 13.8 0.1 0.062 12.5 0.0 1.7 1 0 0 1 1 1 0 Erythronolide synthase docking Mg_chelatase PF01078.16 KEY74163.1 - 0.046 12.8 0.0 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SecA_DEAD PF07517.9 KEY74163.1 - 0.082 12.1 0.0 3.5 6.8 0.0 2.3 2 0 0 2 2 2 0 SecA DEAD-like domain DUF1762 PF08574.5 KEY74165.1 - 3.2e-10 40.2 7.6 3.2e-10 40.2 5.3 3.5 3 1 1 4 4 4 1 Protein of unknown function (DUF1762) His_Phos_1 PF00300.17 KEY74167.1 - 5.8e-25 88.2 0.0 7.1e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) LRR_6 PF13516.1 KEY74168.1 - 3.5e-13 48.1 11.8 0.0015 18.3 0.0 9.0 11 0 0 11 11 11 3 Leucine Rich repeat F-box-like PF12937.2 KEY74168.1 - 8.2e-12 44.6 0.2 2.8e-11 42.9 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KEY74168.1 - 1.8e-09 36.9 0.2 1.8e-09 36.9 0.1 2.3 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.2 KEY74168.1 - 3e-09 36.2 3.2 0.00075 19.0 0.0 5.4 3 2 4 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEY74168.1 - 1.3e-08 33.7 10.6 0.14 12.3 0.0 8.2 7 1 1 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.1 KEY74168.1 - 2.8e-08 33.3 5.1 0.0065 16.2 0.1 4.4 4 0 0 4 4 4 3 Leucine rich repeat PRANC PF09372.5 KEY74168.1 - 0.015 15.2 0.0 0.055 13.4 0.0 1.9 1 0 0 1 1 1 0 PRANC domain Ste50p-SAM PF09235.5 KEY74168.1 - 0.49 10.4 4.6 15 5.7 0.0 4.6 5 1 1 6 6 6 0 Ste50p, sterile alpha motif LRR_7 PF13504.1 KEY74168.1 - 0.65 10.4 25.1 4.4 7.9 0.1 8.2 10 0 0 10 10 10 0 Leucine rich repeat Pkinase PF00069.20 KEY74169.1 - 4.5e-58 196.4 0.0 6.3e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY74169.1 - 3.8e-21 75.3 0.0 5.8e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY74169.1 - 0.00013 21.0 0.0 0.00021 20.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEY74169.1 - 0.002 17.9 0.0 0.0065 16.2 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family PAS_9 PF13426.1 KEY74169.1 - 0.0023 18.2 0.0 0.067 13.5 0.0 3.2 3 1 0 3 3 3 1 PAS domain Kdo PF06293.9 KEY74169.1 - 0.0024 16.9 0.0 0.0042 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KEY74169.1 - 0.0033 16.7 0.1 0.0061 15.9 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.6 KEY74169.1 - 0.27 10.0 0.0 0.44 9.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 zf-rbx1 PF12678.2 KEY74170.1 - 0.096 12.8 4.2 0.22 11.6 2.9 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_2 PF13639.1 KEY74170.1 - 1.9 8.3 13.9 0.49 10.2 5.8 2.7 2 1 0 2 2 2 0 Ring finger domain DUF2361 PF10153.4 KEY74171.1 - 1.4e-32 112.2 6.3 2.4e-32 111.5 4.4 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2361) dsrm PF00035.20 KEY74172.1 - 7.2e-05 23.2 0.1 0.0003 21.3 0.0 2.0 1 1 0 1 1 1 1 Double-stranded RNA binding motif PTS_2-RNA PF01885.11 KEY74173.1 - 1.6e-64 216.6 0.0 1.9e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DNA_mis_repair PF01119.14 KEY74175.1 - 2.5e-34 117.2 0.0 4.4e-34 116.4 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KEY74175.1 - 8.1e-12 44.9 0.0 1.6e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KEY74175.1 - 3.2e-10 39.7 0.0 7.7e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HEAT PF02985.17 KEY74176.1 - 0.0042 17.0 0.5 6.9 7.0 0.0 4.4 3 0 0 3 3 3 1 HEAT repeat BUD22 PF09073.5 KEY74176.1 - 0.15 11.1 5.1 0.23 10.4 3.6 1.2 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 KEY74176.1 - 1.3 7.4 5.2 1.9 6.8 3.6 1.2 1 0 0 1 1 1 0 Daxx Family EFG_IV PF03764.13 KEY74177.1 - 0.05 13.1 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 Elongation factor G, domain IV DUF202 PF02656.10 KEY74178.1 - 3.5e-14 52.7 0.2 3.5e-14 52.7 0.1 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF202) PMP22_Claudin PF00822.15 KEY74178.1 - 0.0038 16.8 1.0 0.0058 16.2 0.7 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Tetraspannin PF00335.15 KEY74178.1 - 0.42 9.8 3.1 1.7 7.8 2.6 1.6 2 0 0 2 2 2 0 Tetraspanin family Lig_chan PF00060.21 KEY74178.1 - 2.3 7.9 4.9 1.2 8.8 0.7 2.0 1 1 1 2 2 2 0 Ligand-gated ion channel TctB PF07331.6 KEY74178.1 - 3.1 7.4 8.4 5.2 6.7 5.8 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family PgaD PF13994.1 KEY74178.1 - 3.3 7.1 5.9 1.9 7.9 1.8 2.0 1 1 1 2 2 2 0 PgaD-like protein ABC_tran PF00005.22 KEY74179.1 - 5e-21 75.4 0.0 5.7e-09 36.3 0.0 3.3 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KEY74179.1 - 3.1e-10 40.4 0.0 0.0076 16.2 0.1 4.1 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 KEY74179.1 - 7.1e-08 33.2 0.0 0.0094 16.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KEY74179.1 - 1.6e-06 27.9 0.0 0.0038 17.1 0.0 2.4 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 KEY74179.1 - 0.00069 19.7 0.0 0.87 9.7 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KEY74179.1 - 0.0017 17.8 0.0 0.089 12.3 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain Miro PF08477.8 KEY74179.1 - 0.0022 18.5 0.0 0.3 11.5 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 KEY74179.1 - 0.0027 18.0 0.0 0.069 13.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEY74179.1 - 0.0072 16.3 0.3 4.6 7.1 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 KEY74179.1 - 0.013 15.3 0.0 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEY74179.1 - 0.053 13.6 0.0 2.1 8.5 0.0 2.6 3 0 0 3 3 2 0 RNA helicase AAA_25 PF13481.1 KEY74179.1 - 0.06 12.7 0.0 5 6.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 KEY74179.1 - 0.061 12.7 0.0 6.2 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.24 KEY74179.1 - 0.073 13.2 0.1 0.65 10.2 0.0 2.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 KEY74179.1 - 0.082 12.6 0.1 12 5.5 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KEY74179.1 - 0.13 12.5 0.0 7.7 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KEY74179.1 - 0.13 11.9 0.0 30 4.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KEY74179.1 - 0.2 11.5 0.0 19 5.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 KEY74179.1 - 0.22 11.0 0.0 2.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_15 PF13175.1 KEY74179.1 - 0.33 9.9 0.0 4.1 6.3 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_13 PF13166.1 KEY74179.1 - 0.35 9.2 0.0 0.48 8.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain UMP1 PF05348.6 KEY74180.1 - 5e-24 84.7 0.0 6.1e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Rad60-SLD_2 PF13881.1 KEY74181.1 - 4.8e-11 42.5 0.0 1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KEY74181.1 - 5.5e-06 25.6 0.0 1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KEY74181.1 - 0.0014 18.7 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Adaptin_N PF01602.15 KEY74182.1 - 3e-134 448.2 7.2 4.8e-134 447.5 5.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KEY74182.1 - 5.2e-18 65.5 2.3 8.9e-18 64.7 0.0 2.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KEY74182.1 - 6e-16 58.5 4.7 2.6e-09 37.2 0.1 4.7 3 1 0 4 4 4 3 HEAT repeats HEAT PF02985.17 KEY74182.1 - 4.5e-12 44.9 2.4 0.00026 20.7 0.0 5.2 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 KEY74182.1 - 7.4e-06 26.2 5.3 0.052 14.0 0.0 6.0 5 1 1 6 6 6 1 HEAT-like repeat Atx10homo_assoc PF09759.4 KEY74182.1 - 0.00019 21.1 0.1 0.081 12.6 0.0 3.9 3 1 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.3 KEY74182.1 - 0.00058 19.2 1.3 0.36 10.1 0.0 2.9 3 0 0 3 3 3 2 CLASP N terminal Arm PF00514.18 KEY74182.1 - 0.0026 17.5 2.1 3 7.7 0.0 4.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DUF4042 PF13251.1 KEY74182.1 - 0.003 17.0 0.0 0.11 11.9 0.0 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4042) DUF1077 PF06417.7 KEY74183.1 - 9.1e-53 176.9 3.1 1.1e-52 176.6 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Syntaxin-18_N PF10496.4 KEY74184.1 - 1.8e-14 53.3 1.1 5.6e-14 51.7 0.1 2.3 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus TEX12 PF15219.1 KEY74184.1 - 0.037 13.9 0.8 0.24 11.4 0.0 2.4 2 0 0 2 2 2 0 Testis-expressed 12 LigA PF07746.6 KEY74184.1 - 0.058 13.4 0.2 0.058 13.4 0.1 2.6 4 0 0 4 4 4 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit SNARE PF05739.14 KEY74184.1 - 0.075 12.7 3.1 0.082 12.6 0.2 2.5 3 1 1 4 4 4 0 SNARE domain HAUS-augmin3 PF14932.1 KEY74184.1 - 2.2 7.4 9.8 1.9 7.6 0.6 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF2937 PF11157.3 KEY74184.1 - 6.4 6.0 9.3 2.3 7.4 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) Aminotran_1_2 PF00155.16 KEY74185.1 - 4.6e-79 266.0 0.0 7.4e-79 265.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II PEMT PF04191.8 KEY74186.1 - 4.2e-55 184.3 12.4 3.5e-33 113.8 2.1 2.8 2 0 0 2 2 2 2 Phospholipid methyltransferase Zn_clus PF00172.13 KEY74187.1 - 3.9e-09 36.2 7.9 3.9e-09 36.2 5.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IBR PF01485.16 KEY74188.1 - 3.3e-15 55.6 40.5 3.2e-08 33.3 6.6 3.4 3 0 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 KEY74188.1 - 3.8e-05 23.4 6.3 3.8e-05 23.4 4.4 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEY74188.1 - 0.00015 21.7 7.4 0.00015 21.7 5.2 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Dicty_REP PF05086.7 KEY74188.1 - 1.4 6.5 10.0 2 6.0 6.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 KEY74188.1 - 8.7 6.1 13.2 17 5.2 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mit_KHE1 PF10173.4 KEY74189.1 - 6.7e-59 198.8 0.0 8.5e-59 198.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Svf1 PF08622.5 KEY74190.1 - 5.8e-123 410.0 0.9 7.4e-123 409.6 0.6 1.1 1 0 0 1 1 1 1 Svf1-like HPIH PF13323.1 KEY74190.1 - 0.023 14.3 0.3 0.04 13.6 0.2 1.3 1 0 0 1 1 1 0 N-terminal domain with HPIH motif GATA PF00320.22 KEY74191.1 - 6.7e-15 54.1 3.0 1.1e-14 53.4 2.1 1.4 1 0 0 1 1 1 1 GATA zinc finger CENP-F_leu_zip PF10473.4 KEY74191.1 - 0.0029 17.4 2.0 0.0029 17.4 1.4 3.0 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 KEY74191.1 - 0.016 15.0 12.5 0.016 15.0 8.6 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding TF_Zn_Ribbon PF08271.7 KEY74191.1 - 0.026 13.8 0.4 0.048 12.9 0.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding DUF4164 PF13747.1 KEY74191.1 - 0.03 14.4 10.2 0.073 13.2 7.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Ribosomal_L12 PF00542.14 KEY74191.1 - 0.16 12.0 2.6 0.4 10.7 1.8 1.6 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain IFP_35_N PF07334.8 KEY74191.1 - 0.32 10.9 8.0 0.18 11.7 2.2 2.7 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Macoilin PF09726.4 KEY74191.1 - 0.84 7.8 13.2 1.2 7.3 9.2 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF342 PF03961.8 KEY74191.1 - 1.6 7.0 7.7 0.06 11.7 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF342) RAB3GAP2_N PF14655.1 KEY74191.1 - 5.7 5.8 6.2 0.89 8.4 0.5 1.9 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Striatin PF08232.7 KEY74191.1 - 6.1 7.1 24.0 5.4 7.3 2.2 3.2 2 1 1 3 3 3 0 Striatin family Histone PF00125.19 KEY74192.1 - 0.0012 18.9 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF2104 PF09877.4 KEY74192.1 - 0.076 12.9 0.0 0.092 12.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2104) CBFD_NFYB_HMF PF00808.18 KEY74192.1 - 0.091 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Acetyltransf_7 PF13508.1 KEY74193.1 - 5.6e-05 23.2 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEY74193.1 - 0.0004 20.3 0.6 0.00082 19.3 0.3 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Pho86 PF11124.3 KEY74193.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 DUF676 PF05057.9 KEY74195.1 - 1.1e-43 149.0 0.0 2.7e-32 111.8 0.0 3.2 2 1 0 2 2 2 2 Putative serine esterase (DUF676) MFS_1 PF07690.11 KEY74196.1 - 4.3e-28 98.0 61.2 2.7e-19 69.0 43.1 4.1 2 1 0 2 2 2 2 Major Facilitator Superfamily MOSC PF03473.12 KEY74199.1 - 4.1e-18 65.1 0.0 6.2e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 KEY74199.1 - 7.2e-15 54.7 0.0 1.2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain His_Phos_2 PF00328.17 KEY74200.1 - 1.5e-125 419.1 0.1 1.9e-125 418.7 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KEY74200.1 - 1.2e-06 28.1 0.0 2.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain DUF3804 PF12707.2 KEY74200.1 - 0.052 13.1 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3804) Pap_E4 PF02711.9 KEY74200.1 - 2.1 9.2 13.7 14 6.5 0.8 3.3 2 0 0 2 2 2 0 E4 protein Utp21 PF04192.7 KEY74201.1 - 5.4e-82 274.4 0.0 7.8e-82 273.9 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 KEY74201.1 - 1e-22 79.0 23.4 2e-06 27.4 0.2 8.7 9 0 0 9 9 9 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KEY74201.1 - 6.3e-07 28.0 0.0 1.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.3 KEY74201.1 - 0.0016 16.6 0.1 3.2 5.7 0.0 3.1 3 0 0 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KEY74201.1 - 0.097 11.3 0.5 1.4 7.5 0.1 2.5 2 1 0 2 2 2 0 Nup133 N terminal like Nol1_Nop2_Fmu PF01189.12 KEY74202.1 - 2.5e-28 99.2 0.0 3.9e-16 59.2 0.0 4.2 3 1 0 3 3 3 3 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 KEY74202.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GTP1_OBG PF01018.17 KEY74203.1 - 6.1e-39 133.1 0.0 4.1e-28 97.9 0.3 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 KEY74203.1 - 2.9e-21 75.6 0.0 4.6e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEY74203.1 - 1.5e-07 30.8 0.0 5.3e-07 29.0 0.0 2.0 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.22 KEY74203.1 - 0.02 15.2 0.6 0.042 14.1 0.0 1.8 2 0 0 2 2 2 0 ABC transporter ArgK PF03308.11 KEY74203.1 - 0.025 13.3 0.0 0.44 9.2 0.0 2.4 2 0 0 2 2 2 0 ArgK protein GTP_EFTU PF00009.22 KEY74203.1 - 0.081 12.3 0.0 7.3 5.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.16 KEY74203.1 - 0.11 11.6 0.0 0.63 9.2 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family TENA_THI-4 PF03070.11 KEY74205.1 - 0.01 15.6 1.1 0.01 15.6 0.7 2.4 2 1 0 2 2 2 0 TENA/THI-4/PQQC family Reo_sigmaC PF04582.7 KEY74205.1 - 0.9 8.6 3.2 6.2 5.9 0.0 2.4 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 KEY74205.1 - 8.5 6.2 7.8 13 5.5 1.2 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 KEY74205.1 - 8.9 5.8 42.7 7.8 6.0 8.5 4.3 2 1 2 4 4 4 0 IncA protein RNA_pol_Rpb5_C PF01191.14 KEY74206.1 - 1e-34 117.9 0.4 2.1e-34 116.9 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KEY74206.1 - 2.7e-28 98.2 0.1 4.6e-28 97.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 KEY74206.1 - 0.022 14.5 0.0 0.12 12.2 0.0 2.1 3 0 0 3 3 3 0 Restriction endonuclease TFCD_C PF12612.3 KEY74208.1 - 6.2e-27 94.2 4.3 6.4e-27 94.2 0.1 3.0 3 1 1 4 4 4 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 KEY74208.1 - 1.5e-05 24.7 1.3 3.4 7.9 0.0 6.4 5 0 0 5 5 5 1 HEAT repeat Vac14_Fab1_bd PF12755.2 KEY74208.1 - 0.076 13.4 0.2 1.4 9.3 0.0 2.9 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Glyco_hydro_76 PF03663.9 KEY74209.1 - 3.5e-44 151.6 0.8 3.5e-44 151.6 0.5 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KEY74209.1 - 2.6e-05 23.4 0.0 0.45 9.5 0.0 3.3 1 1 2 3 3 3 3 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 KEY74209.1 - 0.021 13.0 0.0 2.4 6.3 0.0 2.4 1 1 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) SH3_9 PF14604.1 KEY74211.1 - 6.8e-11 41.5 3.6 7.3e-11 41.4 0.3 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KEY74211.1 - 0.27 10.6 2.4 0.64 9.4 1.6 1.7 1 0 0 1 1 1 0 SH3 domain Anoctamin PF04547.7 KEY74212.1 - 5.4e-119 397.7 5.6 6.6e-119 397.5 3.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF3503 PF12011.3 KEY74212.1 - 0.089 12.5 0.1 4.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3503) Metallophos PF00149.23 KEY74213.1 - 3.9e-11 42.7 2.8 9.4e-11 41.4 1.9 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEY74213.1 - 2.4e-05 24.2 0.0 4.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 KEY74213.1 - 0.17 11.0 0.0 0.43 9.6 0.0 1.6 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily WSC PF01822.14 KEY74214.1 - 1.2e-08 34.7 3.5 1.2e-08 34.7 2.4 2.5 2 0 0 2 2 2 1 WSC domain MIP-T3 PF10243.4 KEY74214.1 - 0.05 12.0 17.1 0.08 11.4 11.8 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Fungal_trans PF04082.13 KEY74215.1 - 4.3e-59 199.5 0.1 6.1e-59 199.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KEY74215.1 - 5.6e-10 38.9 7.8 0.0002 21.4 0.5 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY74215.1 - 1.3e-07 31.3 6.0 0.0045 17.2 0.8 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEY74215.1 - 0.97 9.8 12.5 0.15 12.4 1.5 3.4 3 0 0 3 3 3 0 Zinc-finger double domain SAP30_Sin3_bdg PF13867.1 KEY74216.1 - 1.4e-11 44.0 0.1 2.6e-10 40.0 0.0 2.2 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 CTDII PF01556.13 KEY74217.1 - 5.2e-28 96.7 0.8 7.4e-22 77.0 0.0 3.1 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 KEY74217.1 - 3.2e-24 84.4 3.1 6.4e-24 83.4 2.1 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KEY74217.1 - 7e-12 45.2 20.9 1.3e-11 44.3 14.5 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KEY74217.1 - 7.3 6.3 9.2 15 5.2 0.9 2.6 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DnaJ PF00226.26 KEY74218.1 - 3.9e-13 48.9 1.1 3.9e-13 48.9 0.7 2.3 2 1 1 3 3 3 1 DnaJ domain Alpha_L_fucos PF01120.12 KEY74218.1 - 0.067 12.0 4.7 0.087 11.7 3.2 1.1 1 0 0 1 1 1 0 Alpha-L-fucosidase DEAD PF00270.24 KEY74219.1 - 4.8e-45 153.0 0.0 2.5e-44 150.7 0.0 2.1 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEY74219.1 - 4.7e-22 77.6 0.2 1.8e-21 75.7 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 KEY74219.1 - 2.6e-18 65.5 2.1 6.3e-18 64.3 1.5 1.7 1 0 0 1 1 1 1 DBP10CT (NUC160) domain SNF2_N PF00176.18 KEY74219.1 - 0.00023 20.0 0.0 0.00049 18.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KEY74219.1 - 0.0029 17.4 0.0 0.011 15.5 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit FNIP_N PF14636.1 KEY74220.1 - 1e-30 106.9 0.0 1e-30 106.9 0.0 3.6 3 1 0 3 3 3 1 Folliculin-interacting protein N-terminus DUF3608 PF12257.3 KEY74222.1 - 5.1e-70 235.5 0.0 1.4e-69 234.1 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 KEY74222.1 - 1.9e-28 98.0 0.0 4.8e-28 96.7 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Na_Ca_ex PF01699.19 KEY74223.1 - 8.7e-47 158.2 29.6 1.1e-23 83.4 8.6 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Nipped-B_C PF12830.2 KEY74224.1 - 3.9e-48 163.5 2.3 1.5e-47 161.6 0.6 2.6 2 1 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 KEY74224.1 - 8.8e-10 38.3 1.6 8.8e-10 38.3 1.1 2.2 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 KEY74224.1 - 8.8e-05 22.2 2.0 0.29 11.3 0.0 5.0 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 KEY74224.1 - 0.0011 18.8 0.1 0.034 14.0 0.0 3.1 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KEY74224.1 - 0.031 14.5 2.6 2.2 8.6 0.0 3.9 2 1 1 3 3 3 0 HEAT repeats TFIIS_C PF01096.13 KEY74225.1 - 2.3e-13 49.5 0.8 2.3e-13 49.5 0.6 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KEY74225.1 - 7.3e-05 22.3 3.2 7.3e-05 22.3 2.2 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit OrfB_Zn_ribbon PF07282.6 KEY74225.1 - 0.0039 16.8 8.9 0.0062 16.1 0.5 2.5 2 1 0 2 2 2 1 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.1 KEY74225.1 - 0.0058 16.0 13.8 0.29 10.6 0.1 3.7 4 0 0 4 4 4 1 zinc-ribbon domain HypA PF01155.14 KEY74225.1 - 0.0077 15.8 4.6 1.1 8.9 0.1 2.4 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family DUF523 PF04463.7 KEY74225.1 - 0.03 14.0 0.3 0.039 13.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF523) zf-ribbon_3 PF13248.1 KEY74225.1 - 0.19 10.9 14.6 0.68 9.2 0.1 3.6 3 1 1 4 4 4 0 zinc-ribbon domain DZR PF12773.2 KEY74225.1 - 0.25 11.1 13.0 0.37 10.6 1.4 2.5 2 1 1 3 3 3 0 Double zinc ribbon C1_1 PF00130.17 KEY74225.1 - 0.33 10.6 7.1 0.11 12.2 0.7 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_4 PF14570.1 KEY74225.1 - 0.34 10.5 9.2 4.8 6.8 0.0 3.3 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Lar_restr_allev PF14354.1 KEY74225.1 - 0.35 11.2 10.1 0.22 11.8 0.3 3.0 2 1 0 2 2 2 0 Restriction alleviation protein Lar UPF0547 PF10571.4 KEY74225.1 - 0.35 10.6 0.1 0.35 10.6 0.1 3.5 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 Zn-ribbon_8 PF09723.5 KEY74225.1 - 0.57 10.1 6.9 1 9.3 0.1 2.7 2 1 0 2 2 2 0 Zinc ribbon domain DUF164 PF02591.10 KEY74225.1 - 0.71 9.7 6.0 9 6.2 0.2 3.4 3 0 0 3 3 3 0 Putative zinc ribbon domain zf-ISL3 PF14690.1 KEY74225.1 - 0.87 9.6 0.1 0.87 9.6 0.1 2.8 2 1 1 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-CHY PF05495.7 KEY74225.1 - 0.95 9.6 5.5 11 6.2 0.4 2.3 2 0 0 2 2 2 0 CHY zinc finger NOB1_Zn_bind PF08772.6 KEY74225.1 - 1.7 8.5 10.4 0.37 10.6 0.1 2.9 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like IBR PF01485.16 KEY74225.1 - 1.8 8.5 10.9 1.5 8.7 0.4 2.9 2 1 0 2 2 2 0 IBR domain zf-C2HC5 PF06221.8 KEY74225.1 - 3.2 7.5 8.5 4.1 7.2 1.6 2.8 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type FdhE PF04216.7 KEY74225.1 - 4.2 7.0 6.9 0.18 11.4 0.7 1.6 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation Ribosomal_S27e PF01667.12 KEY74225.1 - 8.7 5.9 8.1 10 5.7 0.1 3.1 2 1 1 3 3 3 0 Ribosomal protein S27 HEAT_2 PF13646.1 KEY74226.1 - 1.1e-26 92.9 7.0 7.2e-14 51.8 0.1 3.7 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.11 KEY74226.1 - 5.8e-19 66.5 4.3 0.013 15.8 0.0 6.6 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 KEY74226.1 - 1e-06 28.9 11.3 0.0096 16.3 0.1 5.0 2 2 2 4 4 4 3 HEAT-like repeat HEAT PF02985.17 KEY74226.1 - 5.8e-06 25.9 4.5 1.5 9.1 0.0 6.3 7 0 0 7 7 7 1 HEAT repeat Arm PF00514.18 KEY74226.1 - 0.00013 21.6 0.6 8.6 6.3 0.0 3.6 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat RuvA_C PF07499.8 KEY74226.1 - 0.21 11.7 4.2 3.8 7.7 0.0 3.7 3 0 0 3 3 3 0 RuvA, C-terminal domain ParA PF10609.4 KEY74227.1 - 1.4e-33 114.5 0.0 2.8e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KEY74227.1 - 1.4e-13 50.7 0.0 2e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KEY74227.1 - 3.6e-05 23.7 0.0 0.00013 21.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 KEY74227.1 - 0.0011 18.1 0.5 0.0031 16.5 0.1 1.9 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 KEY74227.1 - 0.0013 17.8 0.0 0.003 16.6 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.1 KEY74227.1 - 0.0046 16.3 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 KEY74227.1 - 0.0047 16.1 0.0 0.85 8.7 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF258 PF03193.11 KEY74227.1 - 0.017 14.2 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KEY74227.1 - 0.06 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_26 PF13500.1 KEY74227.1 - 0.075 12.6 0.0 9 5.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KEY74227.1 - 0.093 12.4 0.9 1.2 8.9 0.1 2.4 2 1 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 KEY74227.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 KEY74227.1 - 0.14 10.7 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Cofilin_ADF PF00241.15 KEY74228.1 - 1.2e-09 38.1 0.0 1.7e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MoCF_biosynth PF00994.19 KEY74229.1 - 1.7e-35 121.5 0.0 2.8e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ras PF00071.17 KEY74230.1 - 1.1e-58 197.2 0.1 1.3e-58 196.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEY74230.1 - 7.7e-19 68.3 0.0 1.1e-18 67.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEY74230.1 - 2e-08 33.6 0.0 2.5e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEY74230.1 - 1.8e-06 27.5 0.1 8.7e-06 25.2 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEY74230.1 - 0.0018 18.2 0.0 0.0028 17.5 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEY74230.1 - 0.022 14.0 0.0 0.043 13.1 0.0 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B IstB_IS21 PF01695.12 KEY74230.1 - 0.027 13.8 0.5 0.46 9.8 0.1 2.2 1 1 0 1 1 1 0 IstB-like ATP binding protein Gtr1_RagA PF04670.7 KEY74230.1 - 0.044 12.9 0.1 0.056 12.5 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF258 PF03193.11 KEY74230.1 - 0.057 12.6 0.1 0.11 11.6 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 KEY74230.1 - 0.17 11.3 0.1 0.23 10.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 KEY74230.1 - 0.2 11.1 1.3 2.8 7.3 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Acetyltransf_1 PF00583.19 KEY74231.1 - 0.025 14.6 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family YL1 PF05764.8 KEY74231.1 - 2.7 7.5 19.8 5.3 6.5 13.7 1.4 1 0 0 1 1 1 0 YL1 nuclear protein 5-FTHF_cyc-lig PF01812.15 KEY74232.1 - 7.4e-28 97.5 0.0 4.2e-27 95.1 0.0 2.2 2 0 0 2 2 2 1 5-formyltetrahydrofolate cyclo-ligase family Xpo1 PF08389.7 KEY74232.1 - 3.3e-25 88.7 1.5 1e-24 87.1 0.1 2.8 2 1 0 2 2 2 1 Exportin 1-like protein OPT PF03169.10 KEY74233.1 - 4.1e-202 672.9 40.9 4.8e-202 672.7 28.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PC_rep PF01851.17 KEY74234.1 - 2.1e-21 74.8 12.0 9e-07 28.7 0.0 9.2 10 0 0 10 10 10 3 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KEY74234.1 - 9.9e-09 35.3 4.6 0.00039 20.6 0.1 3.5 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.17 KEY74234.1 - 0.037 14.1 0.0 23 5.4 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat RIO1 PF01163.17 KEY74235.1 - 3.9e-40 137.2 0.6 3.9e-39 133.9 0.4 2.0 1 1 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 KEY74235.1 - 1.6e-31 108.1 0.0 3.4e-31 107.1 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 KEY74235.1 - 4.8e-07 29.7 0.2 0.0025 17.5 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KEY74235.1 - 1.2e-06 27.7 0.0 0.012 14.6 0.0 2.5 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family CobT PF06213.7 KEY74235.1 - 1.4 7.9 13.8 2.2 7.3 9.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RRM_1 PF00076.17 KEY74236.1 - 7e-22 76.8 0.0 5.7e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEY74236.1 - 6.4e-14 51.6 0.0 5.7e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEY74236.1 - 0.076 12.8 0.1 14 5.6 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.15 KEY74237.1 - 5.4e-58 196.0 0.0 8.6e-58 195.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KEY74237.1 - 2.3e-32 111.9 1.2 4.5e-32 111.0 0.8 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KEY74237.1 - 5.4e-21 75.1 0.1 4.5e-20 72.2 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KEY74237.1 - 0.023 14.6 0.1 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain MOR2-PAG1_N PF14222.1 KEY74238.1 - 1.5e-215 717.1 0.0 2.2e-215 716.5 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 KEY74238.1 - 3.7e-89 298.9 0.1 1.1e-88 297.4 0.0 2.0 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 KEY74238.1 - 2.9e-36 124.5 6.8 1.4e-16 59.3 0.1 3.6 2 1 1 3 3 3 3 Cell morphogenesis central region HEAT PF02985.17 KEY74238.1 - 0.11 12.5 4.7 7.3 6.9 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat DIM1 PF02966.11 KEY74239.1 - 5.8e-70 232.9 0.2 6.5e-70 232.8 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 KEY74239.1 - 0.014 15.5 0.5 0.023 14.7 0.4 1.4 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin PF00085.15 KEY74239.1 - 0.062 12.9 0.1 0.078 12.6 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DUF2034 PF10356.4 KEY74240.1 - 1.3e-27 96.1 0.0 5.1e-16 58.3 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 KEY74240.1 - 8.7e-08 31.9 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease GST_N_3 PF13417.1 KEY74241.1 - 4.2e-15 55.7 0.0 8.3e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEY74241.1 - 9.7e-12 44.7 0.1 3e-11 43.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KEY74241.1 - 1.9e-11 43.9 0.0 4.3e-11 42.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KEY74241.1 - 2.7e-11 43.2 0.1 4.4e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KEY74241.1 - 7.5e-10 38.5 1.0 1.9e-09 37.2 0.1 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEY74241.1 - 0.0011 19.4 0.1 0.0015 18.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1c PF00749.16 KEY74242.1 - 0.053 12.1 0.6 0.068 11.8 0.4 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain DUF2229 PF09989.4 KEY74242.1 - 0.7 9.3 3.9 0.97 8.8 2.7 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) eIF3_subunit PF08597.5 KEY74242.1 - 1.9 7.9 14.9 0.56 9.7 0.2 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit FAP PF07174.6 KEY74242.1 - 6.8 5.9 16.2 8.6 5.5 11.2 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Lon_C PF05362.8 KEY74243.1 - 4.2e-66 222.1 0.0 7.4e-66 221.3 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KEY74243.1 - 3.4e-37 128.1 0.1 7.2e-37 127.0 0.1 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KEY74243.1 - 8.1e-22 77.8 0.0 2.3e-21 76.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEY74243.1 - 1.1e-06 28.4 0.0 2.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KEY74243.1 - 1.2e-06 28.5 0.0 3.7e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.1 KEY74243.1 - 7.3e-06 25.4 0.0 1.8e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.1 KEY74243.1 - 1.2e-05 25.4 0.0 0.00024 21.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 KEY74243.1 - 4.6e-05 22.2 0.0 9.5e-05 21.2 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 KEY74243.1 - 7e-05 23.6 0.0 0.00035 21.3 0.0 2.3 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KEY74243.1 - 0.00018 20.6 0.0 0.0013 17.8 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KEY74243.1 - 0.00034 20.6 1.7 0.0053 16.7 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 KEY74243.1 - 0.005 16.7 0.0 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEY74243.1 - 0.0077 16.5 0.9 0.03 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KEY74243.1 - 0.027 14.1 0.0 0.067 12.8 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 KEY74243.1 - 0.029 13.7 0.0 0.074 12.4 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF258 PF03193.11 KEY74243.1 - 0.035 13.2 0.0 0.098 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KEY74243.1 - 0.041 14.0 0.0 0.14 12.3 0.0 2.0 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 KEY74243.1 - 0.054 13.2 0.2 1.1 8.9 0.0 2.5 1 1 1 2 2 2 0 NTPase AAA_25 PF13481.1 KEY74243.1 - 0.082 12.2 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KEY74243.1 - 0.15 11.9 0.5 0.3 10.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.8 KEY74243.1 - 0.21 10.2 3.2 1.1 7.9 0.0 2.5 3 0 0 3 3 2 0 TIP49 C-terminus ClpB_D2-small PF10431.4 KEY74243.1 - 0.32 10.9 6.0 0.1 12.4 0.2 2.7 3 0 0 3 3 2 0 C-terminal, D2-small domain, of ClpB protein Pkinase PF00069.20 KEY74244.1 - 1.3e-12 47.4 0.1 1e-10 41.2 0.0 3.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY74244.1 - 1.3e-10 40.7 0.0 2.9e-09 36.3 0.0 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase Cyt-b5 PF00173.23 KEY74245.1 - 6.2e-17 61.1 0.1 2.3e-16 59.3 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 KEY74245.1 - 5e-15 55.6 11.9 5e-15 55.6 8.2 1.6 1 1 1 2 2 2 1 Fatty acid desaturase WD40 PF00400.27 KEY74246.1 - 4.3e-16 58.0 3.0 0.00015 21.5 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Mago-bind PF09282.5 KEY74246.1 - 0.033 13.7 0.4 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Mago binding TFIIB PF00382.14 KEY74247.1 - 0.00066 19.4 0.6 0.026 14.3 0.0 2.9 3 0 0 3 3 3 1 Transcription factor TFIIB repeat Cyclin_N PF00134.18 KEY74247.1 - 0.0011 18.5 0.1 0.034 13.7 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Self-incomp_S1 PF05938.6 KEY74248.1 - 0.1 12.7 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Plant self-incompatibility protein S1 BSP PF04450.7 KEY74250.1 - 4.5e-73 245.0 0.0 5.3e-73 244.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 KEY74250.1 - 4.1e-07 30.1 0.3 9.8e-05 22.3 0.0 2.2 1 1 1 2 2 2 2 Peptidase MA superfamily SprT-like PF10263.4 KEY74250.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 SprT-like family CLASP_N PF12348.3 KEY74251.1 - 2e-125 416.6 0.0 3e-85 285.1 0.0 2.4 2 0 0 2 2 2 2 CLASP N terminal HEAT_2 PF13646.1 KEY74251.1 - 3e-05 24.2 5.0 0.051 13.8 0.0 5.0 3 2 3 6 6 6 1 HEAT repeats HEAT PF02985.17 KEY74251.1 - 3.9e-05 23.3 0.0 1.5 9.1 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 KEY74251.1 - 0.00028 21.2 2.4 1.1 9.7 0.0 4.5 4 0 0 4 4 4 2 HEAT-like repeat MMS19_C PF12460.3 KEY74251.1 - 0.085 11.5 0.1 0.45 9.1 0.0 2.0 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal RhoGAP PF00620.22 KEY74252.1 - 7.5e-46 155.4 0.5 4.9e-45 152.8 0.0 2.5 2 1 0 2 2 2 1 RhoGAP domain LIM PF00412.17 KEY74252.1 - 1.4e-13 50.6 17.0 6.2e-09 35.7 1.4 2.4 2 0 0 2 2 2 2 LIM domain Zn-ribbon_8 PF09723.5 KEY74252.1 - 2.3 8.2 18.1 0.53 10.2 0.8 3.8 3 1 0 3 3 3 0 Zinc ribbon domain Desulfoferrod_N PF06397.7 KEY74252.1 - 5.5 6.4 8.0 33 3.9 0.0 3.5 2 1 1 3 3 3 0 Desulfoferrodoxin, N-terminal domain SlyX PF04102.7 KEY74252.1 - 7.2 7.0 10.3 0.25 11.7 1.3 3.0 2 1 1 3 3 3 0 SlyX rRNA_processing PF08524.6 KEY74253.1 - 6.2e-05 22.8 27.8 0.00025 20.8 2.7 2.1 1 1 1 2 2 2 2 rRNA processing DUF4210 PF13915.1 KEY74254.1 - 2.2e-26 91.8 0.0 5.2e-26 90.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 KEY74254.1 - 3e-20 71.8 0.2 8.9e-20 70.3 0.1 1.9 1 0 0 1 1 1 1 Chromosome segregation during meiosis PPR_2 PF13041.1 KEY74255.1 - 1.2e-18 66.7 13.1 0.00038 20.3 0.0 9.0 7 2 3 10 10 10 7 PPR repeat family PPR PF01535.15 KEY74255.1 - 3e-13 48.7 15.8 0.14 12.2 0.0 10.7 11 0 0 11 11 11 3 PPR repeat PPR_3 PF13812.1 KEY74255.1 - 7.7e-12 44.5 7.8 4.4 7.8 0.0 10.4 11 0 0 11 11 11 4 Pentatricopeptide repeat domain TPR_14 PF13428.1 KEY74255.1 - 1.1e-09 38.0 6.5 1.9 9.3 0.0 9.0 9 2 1 10 10 10 2 Tetratricopeptide repeat PPR_1 PF12854.2 KEY74255.1 - 4.7e-06 25.9 0.2 0.12 11.8 0.0 5.4 5 0 0 5 5 5 1 PPR repeat TPR_4 PF07721.9 KEY74255.1 - 0.011 16.0 0.1 1.1 9.8 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PI3_PI4_kinase PF00454.22 KEY74256.1 - 6.1e-39 133.8 0.0 9.1e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Methyltransf_23 PF13489.1 KEY74257.1 - 1.9e-13 50.4 0.0 2.6e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY74257.1 - 9.7e-12 45.2 0.0 1.7e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY74257.1 - 1.2e-09 37.9 0.0 7e-09 35.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY74257.1 - 9.6e-09 35.5 0.0 1.7e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY74257.1 - 3.8e-08 33.7 0.0 8.7e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY74257.1 - 8.4e-08 32.7 0.0 8.7e-07 29.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY74257.1 - 2.3e-05 24.3 0.0 4.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY74257.1 - 4.6e-05 22.6 0.0 0.0002 20.5 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 KEY74257.1 - 0.00036 19.6 0.0 0.00053 19.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 KEY74257.1 - 0.007 15.4 0.0 0.018 14.1 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 KEY74257.1 - 0.033 14.1 0.0 0.13 12.2 0.0 1.8 1 1 1 2 2 2 0 FtsJ-like methyltransferase YqeY PF09424.5 KEY74258.1 - 2.9e-24 85.5 7.8 3.5e-24 85.3 5.4 1.1 1 0 0 1 1 1 1 Yqey-like protein SRP54_N PF02881.14 KEY74258.1 - 0.068 13.2 0.6 0.16 12.1 0.4 1.7 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain ApoLp-III PF07464.6 KEY74258.1 - 0.58 10.1 7.8 1.1 9.3 5.4 1.5 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Ribonuc_L-PSP PF01042.16 KEY74259.1 - 2.2e-26 91.9 0.0 2.4e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF2077 PF09850.4 KEY74259.1 - 0.063 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) Tir_receptor_M PF03549.9 KEY74259.1 - 0.13 12.3 0.2 0.34 11.0 0.0 1.8 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) intimin-binding domain Sulf_transp PF04143.9 KEY74260.1 - 8.4e-10 38.5 8.4 8.4e-10 38.5 5.9 4.7 4 1 0 4 4 4 2 Sulphur transport ADH_zinc_N PF00107.21 KEY74261.1 - 5.3e-20 71.2 0.0 8.1e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY74261.1 - 2.6e-07 31.6 0.0 6e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY74261.1 - 2e-05 24.2 0.0 4.9e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_7 PF13241.1 KEY74261.1 - 0.13 12.5 0.1 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pfg27 PF09216.5 KEY74262.1 - 0.02 14.4 0.1 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 Pfg27 CWC25 PF12542.3 KEY74262.1 - 0.075 13.4 4.9 0.14 12.5 3.4 1.5 1 0 0 1 1 1 0 Pre-mRNA splicing factor Ribosomal_L11_N PF03946.9 KEY74263.1 - 6.1e-25 86.4 0.1 8.9e-25 85.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KEY74263.1 - 4.1e-24 84.5 0.5 9.2e-24 83.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Pkinase PF00069.20 KEY74264.1 - 5.6e-60 202.6 0.0 1.4e-59 201.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Cpn10 PF00166.16 KEY74264.1 - 5.2e-26 90.4 0.0 1.1e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pkinase_Tyr PF07714.12 KEY74264.1 - 2.5e-21 75.9 0.0 6.2e-21 74.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KEY74264.1 - 0.0056 16.4 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEY74264.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Glyco_hydro_61 PF03443.9 KEY74265.1 - 2.2e-45 155.1 0.0 2.7e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ras PF00071.17 KEY74266.1 - 3e-65 218.5 0.1 3.6e-65 218.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEY74266.1 - 1.5e-19 70.6 0.0 2.1e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEY74266.1 - 2.1e-13 49.8 0.1 2.4e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEY74266.1 - 6.7e-07 28.9 0.1 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KEY74266.1 - 2.9e-06 26.5 0.0 3.4e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KEY74266.1 - 0.0035 17.2 0.0 0.0051 16.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KEY74266.1 - 0.017 14.3 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.24 KEY74266.1 - 0.081 13.1 0.0 5.2 7.2 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEY74266.1 - 0.082 13.0 0.0 0.23 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEY74266.1 - 0.098 12.2 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 KEY74266.1 - 0.099 11.8 0.0 0.26 10.4 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 G-alpha PF00503.15 KEY74266.1 - 0.13 10.9 0.5 14 4.2 0.0 2.7 1 1 1 2 2 2 0 G-protein alpha subunit HLH PF00010.21 KEY74267.1 - 0.088 12.5 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain AAA PF00004.24 KEY74268.1 - 8.1e-51 171.6 0.0 6.8e-39 133.0 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEY74268.1 - 1.4e-06 28.4 4.0 0.01 15.8 0.3 4.1 3 2 1 4 4 4 2 AAA ATPase domain AAA_19 PF13245.1 KEY74268.1 - 2.3e-05 24.0 3.3 0.023 14.4 0.0 4.4 4 1 0 4 4 4 2 Part of AAA domain AAA_5 PF07728.9 KEY74268.1 - 6e-05 22.7 0.0 0.085 12.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEY74268.1 - 6.2e-05 23.1 0.0 0.16 12.1 0.0 3.3 2 1 1 3 3 3 2 AAA domain RuvB_N PF05496.7 KEY74268.1 - 0.00021 20.3 0.0 0.0023 17.0 0.0 2.6 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KEY74268.1 - 0.00039 20.4 0.0 0.027 14.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KEY74268.1 - 0.0018 17.6 6.9 0.35 10.2 0.2 4.2 3 2 1 4 4 4 1 AAA domain NACHT PF05729.7 KEY74268.1 - 0.017 14.7 2.3 1.5 8.4 0.3 3.5 3 1 1 4 4 4 0 NACHT domain RNA_helicase PF00910.17 KEY74268.1 - 0.037 14.1 0.0 9.5 6.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 KEY74268.1 - 0.06 13.2 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KEY74268.1 - 0.093 11.8 0.5 1.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Vps4_C PF09336.5 KEY74268.1 - 0.13 12.1 0.0 2.4 8.1 0.0 2.7 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Rad17 PF03215.10 KEY74268.1 - 0.18 10.4 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SMK-1 PF04802.10 KEY74269.1 - 3e-75 252.0 1.4 3e-75 252.0 1.0 2.1 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 Glycos_transf_2 PF00535.21 KEY74271.1 - 2.8e-24 85.6 0.0 6.7e-24 84.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KEY74271.1 - 1.7e-10 41.1 0.6 2.4e-07 30.8 0.0 3.1 2 1 1 3 3 3 2 Glycosyltransferase like family 2 SE PF08491.5 KEY74272.1 - 1.3e-84 283.2 0.0 1.8e-84 282.8 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 KEY74272.1 - 3.3e-08 32.8 0.3 5.7e-07 28.7 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KEY74272.1 - 2.7e-06 26.6 1.5 0.00011 21.3 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KEY74272.1 - 0.00014 21.7 0.2 0.00032 20.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KEY74272.1 - 0.0012 19.1 0.2 0.0026 18.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEY74272.1 - 0.0014 17.5 0.2 0.0058 15.5 0.1 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KEY74272.1 - 0.0054 15.6 0.1 0.0084 14.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KEY74272.1 - 0.0082 16.0 0.6 0.028 14.2 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEY74272.1 - 0.0088 15.1 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.11 KEY74272.1 - 0.0096 15.3 0.1 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KEY74272.1 - 0.011 15.4 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KEY74272.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 KEY74272.1 - 0.016 14.2 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.15 KEY74272.1 - 0.033 14.2 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 KEY74272.1 - 0.043 12.7 0.1 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.16 KEY74272.1 - 0.086 12.6 0.3 0.16 11.7 0.2 1.4 1 0 0 1 1 1 0 ThiF family DUF3482 PF11981.3 KEY74273.1 - 0.068 12.3 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Aldo_ket_red PF00248.16 KEY74274.1 - 4.1e-57 193.1 0.2 1.9e-56 190.9 0.1 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family DUF1279 PF06916.8 KEY74274.1 - 0.042 14.1 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) WD40 PF00400.27 KEY74276.1 - 1.5e-16 59.5 5.2 2.2e-05 24.1 0.0 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat EIF_2_alpha PF07541.7 KEY74277.1 - 3.2e-38 129.9 0.0 6.2e-38 129.0 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KEY74277.1 - 1.2e-14 54.0 0.8 2.5e-14 53.1 0.6 1.5 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.4 KEY74277.1 - 0.096 12.6 0.9 0.18 11.7 0.2 1.8 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 Mito_carr PF00153.22 KEY74278.1 - 8.3e-61 201.7 0.1 2.5e-20 71.9 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S24 PF00717.18 KEY74278.1 - 7.8e-05 22.2 0.1 0.00028 20.4 0.1 2.0 1 1 0 1 1 1 1 Peptidase S24-like Ribosomal_L23 PF00276.15 KEY74280.1 - 6e-14 51.7 0.0 1.1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 MT-A70 PF05063.9 KEY74281.1 - 1.2e-35 122.6 0.1 1.7e-35 122.1 0.1 1.2 1 0 0 1 1 1 1 MT-A70 Methyltransf_26 PF13659.1 KEY74281.1 - 0.012 15.6 0.1 0.036 14.0 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain Mito_carr PF00153.22 KEY74282.1 - 2.8e-63 209.6 0.1 9.7e-22 76.4 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein ORC4_C PF14629.1 KEY74283.1 - 3.6e-55 186.5 0.0 5.2e-55 185.9 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 KEY74283.1 - 3.4e-16 59.7 0.1 8.6e-15 55.1 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain PHD PF00628.24 KEY74283.1 - 7.5e-11 41.5 7.1 1.3e-10 40.8 4.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KEY74283.1 - 9.4e-11 40.8 2.5 1.9e-10 39.8 1.8 1.5 1 0 0 1 1 1 1 PHD-finger AAA_22 PF13401.1 KEY74283.1 - 2.9e-09 37.1 0.0 7.4e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KEY74283.1 - 1.8e-08 34.6 0.0 4.3e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KEY74283.1 - 2.4e-08 33.8 0.0 6.8e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 KEY74283.1 - 0.00014 21.7 0.0 0.00042 20.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KEY74283.1 - 0.0004 20.1 0.0 0.00098 18.8 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase DUF815 PF05673.8 KEY74283.1 - 0.00069 18.6 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NB-ARC PF00931.17 KEY74283.1 - 0.0017 17.2 0.0 0.0028 16.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.9 KEY74283.1 - 0.0023 16.9 0.0 0.0041 16.1 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA_19 PF13245.1 KEY74283.1 - 0.0028 17.3 0.0 0.0065 16.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 KEY74283.1 - 0.0085 15.5 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP-synt_ab PF00006.20 KEY74283.1 - 0.01 15.3 0.0 0.033 13.6 0.0 1.8 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FYVE_2 PF02318.11 KEY74283.1 - 0.021 14.7 1.2 0.041 13.7 0.8 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger AAA_30 PF13604.1 KEY74283.1 - 0.023 14.3 0.0 0.094 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KEY74283.1 - 0.028 14.1 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 KEY74283.1 - 0.029 13.8 0.0 6.2 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 KEY74283.1 - 0.029 14.5 0.0 0.075 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.13 KEY74283.1 - 0.03 13.8 0.0 0.074 12.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.1 KEY74283.1 - 0.033 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KEY74283.1 - 0.037 14.3 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 KEY74283.1 - 0.045 14.5 0.1 0.11 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KEY74283.1 - 0.046 13.5 0.0 0.19 11.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KEY74283.1 - 0.057 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KEY74283.1 - 0.062 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain C1_1 PF00130.17 KEY74283.1 - 0.081 12.6 0.4 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) G-alpha PF00503.15 KEY74283.1 - 0.091 11.4 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit MobB PF03205.9 KEY74283.1 - 0.097 12.3 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Pox_A32 PF04665.7 KEY74283.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein cobW PF02492.14 KEY74283.1 - 0.12 11.7 0.0 0.32 10.4 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KEY74283.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation zf-UDP PF14569.1 KEY74283.1 - 0.16 11.7 1.4 1.2 8.9 1.2 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger ORC2 PF04084.9 KEY74283.1 - 0.21 10.3 0.3 1.5 7.5 0.0 2.0 2 0 0 2 2 2 0 Origin recognition complex subunit 2 DUF4206 PF13901.1 KEY74283.1 - 1.6 8.2 4.4 7.6 6.0 3.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4206) C1_3 PF07649.7 KEY74283.1 - 3.2 7.8 5.1 8.2 6.5 3.5 1.7 1 1 0 1 1 1 0 C1-like domain DUF605 PF04652.11 KEY74284.1 - 9.3 5.5 24.8 13 5.0 17.2 1.2 1 0 0 1 1 1 0 Vta1 like Nop14 PF04147.7 KEY74285.1 - 0.0038 15.2 7.4 0.0046 14.9 5.1 1.1 1 0 0 1 1 1 1 Nop14-like family DUF2457 PF10446.4 KEY74285.1 - 0.023 13.4 12.6 0.044 12.5 8.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RGS PF00615.14 KEY74286.1 - 1.1e-35 122.3 0.7 7e-35 119.6 0.1 2.5 4 0 0 4 4 4 1 Regulator of G protein signaling domain DEP PF00610.16 KEY74286.1 - 1.8e-24 85.2 0.0 1.4e-20 72.7 0.0 3.2 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CopK PF11525.3 KEY74286.1 - 0.081 12.5 0.1 0.26 10.9 0.1 1.8 1 0 0 1 1 1 0 Copper resistance protein K Replic_Relax PF13814.1 KEY74286.1 - 0.092 12.5 0.1 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Replication-relaxation Gly_transf_sug PF04488.10 KEY74288.1 - 6.4e-08 32.9 0.0 1.8e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KEY74288.1 - 1.4e-06 27.6 0.0 2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 KEY74288.1 - 0.002 16.6 0.0 0.15 10.4 0.0 2.3 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain CDC73 PF05179.9 KEY74289.1 - 9.5e-45 153.0 0.0 2.1e-44 151.9 0.0 1.6 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Bystin PF05291.6 KEY74291.1 - 7.1e-126 419.1 0.0 9.8e-126 418.7 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF383 PF04063.9 KEY74292.1 - 1.2e-67 227.1 0.2 6.3e-67 224.8 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 KEY74292.1 - 2.3e-23 81.5 1.5 5.6e-23 80.2 1.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF384) V-ATPase_H_N PF03224.9 KEY74292.1 - 0.0037 16.4 0.0 0.006 15.7 0.0 1.5 1 1 0 1 1 1 1 V-ATPase subunit H HEAT_2 PF13646.1 KEY74292.1 - 0.0053 17.0 0.1 0.11 12.7 0.0 2.6 2 0 0 2 2 2 1 HEAT repeats Proteasom_PSMB PF10508.4 KEY74292.1 - 0.0096 14.2 0.1 0.18 9.9 0.0 2.5 2 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit Kelch_5 PF13854.1 KEY74293.1 - 4.1e-14 52.1 10.4 1.2e-12 47.5 1.4 3.7 4 1 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 KEY74293.1 - 1.5e-06 28.1 0.9 1.5e-06 28.1 0.7 4.4 4 2 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.1 KEY74293.1 - 0.00019 21.1 7.1 1.7 8.4 0.2 6.1 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KEY74293.1 - 0.0015 18.6 7.4 0.24 11.6 1.1 4.8 4 1 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 KEY74293.1 - 0.3 10.6 4.1 1.9 8.1 0.0 3.1 2 0 0 2 2 2 0 Kelch motif DUF4191 PF13829.1 KEY74293.1 - 1 8.4 2.1 0.92 8.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) VWA_N PF08399.6 KEY74294.1 - 1.6 9.3 5.6 0.22 12.1 0.6 1.9 2 0 0 2 2 2 0 VWA N-terminal BIR PF00653.16 KEY74295.1 - 4.4e-42 142.3 1.6 4e-20 72.0 0.0 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain AT_hook PF02178.14 KEY74295.1 - 0.056 13.1 34.3 0.09 12.5 1.1 5.0 5 0 0 5 5 5 0 AT hook motif CoA_binding_2 PF13380.1 KEY74296.1 - 1.9e-15 57.0 0.1 3.5e-15 56.1 0.0 1.4 1 1 0 1 1 1 1 CoA binding domain PAAR_motif PF05488.8 KEY74296.1 - 0.018 15.0 0.4 0.036 14.0 0.3 1.5 1 0 0 1 1 1 0 PAAR motif Methyltransf_11 PF08241.7 KEY74297.1 - 1.9e-18 66.6 0.0 3.3e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY74297.1 - 6.9e-12 45.9 0.0 1.5e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY74297.1 - 2.1e-09 37.7 0.0 5.6e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY74297.1 - 1.4e-08 35.0 0.0 2.3e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY74297.1 - 3.1e-08 33.5 0.0 4.7e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY74297.1 - 1.7e-07 30.9 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY74297.1 - 2.6e-06 26.7 0.0 3.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.7 KEY74297.1 - 5.9e-06 25.3 0.0 1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.9 KEY74297.1 - 6.4e-05 22.3 0.0 9.8e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KEY74297.1 - 0.00015 21.7 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 KEY74297.1 - 0.012 14.2 0.0 0.017 13.8 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_8 PF05148.10 KEY74297.1 - 0.055 13.0 0.0 0.26 10.8 0.0 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase Mn_catalase PF05067.7 KEY74297.1 - 0.061 12.0 0.0 0.093 11.4 0.0 1.2 1 0 0 1 1 1 0 Manganese containing catalase RrnaAD PF00398.15 KEY74297.1 - 0.089 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TehB PF03848.9 KEY74297.1 - 0.17 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Peptidase_M3 PF01432.15 KEY74298.1 - 2.3e-149 498.3 0.0 3e-149 497.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 EF-hand_7 PF13499.1 KEY74298.1 - 2.9e-11 43.3 0.1 5.8e-07 29.5 0.0 2.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_9 PF14658.1 KEY74298.1 - 2.2e-08 33.8 0.0 0.0013 18.5 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.1 KEY74298.1 - 1.1e-07 31.1 0.6 0.014 15.2 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KEY74298.1 - 4.7e-06 25.5 0.3 0.13 11.6 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KEY74298.1 - 0.00034 20.1 0.7 0.04 13.5 0.0 3.8 3 1 1 4 4 4 1 EF-hand domain pair Peptidase_M91 PF14891.1 KEY74298.1 - 0.044 13.8 0.2 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 Effector protein MFS_1 PF07690.11 KEY74299.1 - 7.2e-29 100.5 35.0 7.2e-29 100.5 24.3 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily 7tm_2 PF00002.19 KEY74300.1 - 1e-10 41.1 10.0 1e-10 41.1 7.0 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.16 KEY74300.1 - 1.4e-08 34.1 2.2 2.8e-08 33.2 1.5 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 KEY74300.1 - 0.012 15.2 13.1 0.021 14.3 9.1 1.4 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 MFS_1 PF07690.11 KEY74301.1 - 5.5e-11 41.7 34.2 5.5e-11 41.7 23.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.2 KEY74302.1 - 0.00046 19.8 1.0 0.0016 18.0 0.0 2.4 3 0 0 3 3 3 1 F-box-like Sulfate_transp PF00916.15 KEY74303.1 - 4.3e-64 216.2 12.0 8.1e-64 215.3 8.3 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KEY74303.1 - 8.1e-31 105.5 4.1 8.1e-31 105.5 2.9 3.5 3 1 1 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KEY74303.1 - 2.8e-10 39.6 0.0 5.1e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 STAS domain Glyco_transf_22 PF03901.12 KEY74304.1 - 6.8e-85 285.5 17.5 8e-85 285.3 12.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gar1 PF04410.9 KEY74305.1 - 4.9e-46 155.9 0.1 4.9e-46 155.9 0.0 2.0 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region Peptidase_M28 PF04389.12 KEY74306.1 - 4.3e-27 95.0 0.4 1.9e-26 92.9 0.1 1.9 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 KEY74306.1 - 0.00011 21.8 0.1 0.00018 21.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF2525 PF10733.4 KEY74306.1 - 0.1 12.4 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2525) Sld5 PF05916.6 KEY74308.1 - 4e-24 84.9 0.0 1.5e-23 83.0 0.0 1.9 2 1 0 2 2 2 1 GINS complex protein Acetyltransf_7 PF13508.1 KEY74309.1 - 1.6e-05 24.9 0.1 6.1e-05 23.1 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEY74309.1 - 4.7e-05 23.2 0.1 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ProRS-C_1 PF09180.6 KEY74310.1 - 1.8e-20 72.6 0.1 3.4e-20 71.7 0.1 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 KEY74310.1 - 3.2e-19 69.1 0.0 5.3e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KEY74310.1 - 9.8e-16 57.4 0.0 2.8e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain Cpn60_TCP1 PF00118.19 KEY74311.1 - 1.4e-141 472.4 10.0 1.6e-141 472.3 7.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Euplotes_phero PF05842.6 KEY74312.1 - 7.2 6.9 9.7 1.3 9.4 2.7 2.2 2 0 0 2 2 2 0 Euplotes octocarinatus mating pheromone protein UCR_TM PF02921.9 KEY74313.1 - 5.4e-18 64.9 1.0 5.4e-18 64.9 0.7 1.8 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 KEY74313.1 - 8.6e-18 63.7 0.0 1.4e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain MMS1_N PF10433.4 KEY74314.1 - 1.1e-78 264.5 0.0 1.7e-78 263.9 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KEY74314.1 - 3.1e-64 217.1 0.0 1.3e-63 215.0 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region SGL PF08450.7 KEY74314.1 - 0.11 11.8 0.1 6.4 6.0 0.0 3.6 5 0 0 5 5 5 0 SMP-30/Gluconolaconase/LRE-like region RNA_pol_Rpb4 PF03874.11 KEY74315.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb4 R3H-assoc PF13902.1 KEY74316.1 - 1.8e-21 76.5 3.4 3.6e-21 75.4 2.3 1.5 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 KEY74316.1 - 1.2e-05 24.8 0.0 3.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 R3H domain PQ-loop PF04193.9 KEY74317.1 - 2e-22 78.4 17.4 1.6e-13 49.9 0.6 3.5 3 1 1 4 4 4 2 PQ loop repeat DUF3796 PF12676.2 KEY74317.1 - 0.048 13.8 0.1 0.048 13.8 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3796) DUF1129 PF06570.6 KEY74317.1 - 2.2 7.5 5.5 0.29 10.4 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF2975 PF11188.3 KEY74317.1 - 7.7 6.2 11.7 0.67 9.6 0.7 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF2975) WD40 PF00400.27 KEY74318.1 - 0.011 15.5 16.0 5.4 7.0 1.1 6.5 7 0 0 7 7 7 0 WD domain, G-beta repeat HTH_32 PF13565.1 KEY74319.1 - 0.0042 17.8 0.4 0.0042 17.8 0.2 1.9 1 1 1 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 KEY74319.1 - 0.019 15.1 0.8 0.029 14.5 0.1 1.6 1 1 1 2 2 2 0 Winged helix-turn helix Nitrate_red_gam PF02665.9 KEY74320.1 - 0.03 13.6 0.5 0.051 12.9 0.3 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit TMEM154 PF15102.1 KEY74320.1 - 0.24 11.0 8.4 2.7 7.7 5.8 2.2 1 1 0 1 1 1 0 TMEM154 protein family Glyco_transf_28 PF03033.15 KEY74321.1 - 3.2e-25 88.5 0.1 7e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KEY74321.1 - 0.00014 20.5 0.0 0.00034 19.3 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase zf-Tim10_DDP PF02953.10 KEY74321.1 - 0.11 11.7 0.7 0.29 10.4 0.0 1.9 2 0 0 2 2 2 0 Tim10/DDP family zinc finger Ion_trans PF00520.26 KEY74322.1 - 2e-07 30.4 17.1 2.2e-07 30.3 10.2 2.3 2 1 0 2 2 2 1 Ion transport protein DUF3814 PF12769.2 KEY74322.1 - 0.014 15.5 0.3 0.04 14.0 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3814) Cellulase PF00150.13 KEY74323.1 - 1.9e-11 43.7 0.0 6.3e-11 42.0 0.0 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SH3_1 PF00018.23 KEY74325.1 - 3.2e-27 93.6 0.0 1e-13 50.4 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KEY74325.1 - 5.5e-19 67.4 0.2 3.8e-09 36.0 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.19 KEY74325.1 - 1.6e-14 53.6 0.0 2.7e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 KEY74325.1 - 9e-13 47.5 0.0 1.1e-07 31.2 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 KEY74325.1 - 4.8e-10 38.9 0.1 8.5e-10 38.1 0.1 1.3 1 0 0 1 1 1 1 PB1 domain Rad60-SLD PF11976.3 KEY74325.1 - 0.038 13.6 0.1 0.82 9.4 0.0 2.4 1 1 1 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like SAC3_GANP PF03399.11 KEY74326.1 - 1.5e-62 210.8 0.2 1.9e-62 210.4 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KEY74326.1 - 0.023 14.4 0.2 0.065 13.0 0.0 1.8 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 EAP30 PF04157.11 KEY74327.1 - 3.2e-55 186.7 0.0 4.2e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 KEY74327.1 - 1.1e-26 92.4 0.0 2.1e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 KEY74327.1 - 0.0003 19.7 1.0 0.0003 19.7 0.7 2.6 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others GRAM PF02893.15 KEY74327.1 - 0.0018 17.7 0.0 0.0036 16.7 0.0 1.5 1 0 0 1 1 1 1 GRAM domain zf-Sec23_Sec24 PF04810.10 KEY74327.1 - 0.011 15.2 6.3 0.044 13.3 0.4 2.7 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DZR PF12773.2 KEY74327.1 - 0.052 13.3 0.4 0.052 13.3 0.3 2.2 2 1 0 2 2 2 0 Double zinc ribbon HTH_Tnp_Tc5 PF03221.11 KEY74328.1 - 5.1e-17 61.4 0.3 2.7e-16 59.1 0.1 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain SGL PF08450.7 KEY74328.1 - 1.9e-16 60.1 0.0 3e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 KEY74328.1 - 8.8e-07 28.5 2.0 0.65 10.0 0.1 4.0 4 0 0 4 4 4 3 NHL repeat Reg_prop PF07494.6 KEY74328.1 - 0.015 15.2 0.1 7.1 7.0 0.0 3.0 2 0 0 2 2 2 0 Two component regulator propeller Str_synth PF03088.11 KEY74328.1 - 0.13 12.2 0.0 0.4 10.7 0.0 1.7 1 1 0 1 1 1 0 Strictosidine synthase DUF2611 PF11022.3 KEY74329.1 - 9e-27 92.9 0.1 1e-26 92.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) MTP18 PF10558.4 KEY74330.1 - 1.7e-68 229.2 0.1 2.1e-68 228.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) zf-AN1 PF01428.11 KEY74331.1 - 5.1e-25 87.0 21.4 1.2e-12 47.4 4.2 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 KEY74331.1 - 0.002 17.9 14.3 0.0044 16.8 2.1 2.5 2 0 0 2 2 2 2 IBR domain Transp_Tc5_C PF04236.10 KEY74331.1 - 0.024 14.8 13.3 0.38 11.0 2.5 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Rad4 PF03835.10 KEY74332.1 - 1.8e-29 101.9 0.9 1.8e-29 101.9 0.7 2.1 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KEY74332.1 - 7e-27 92.9 0.3 1.6e-26 91.8 0.1 1.7 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KEY74332.1 - 3.7e-19 67.9 0.3 8.9e-19 66.7 0.2 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KEY74332.1 - 3.7e-16 59.1 1.0 3.7e-16 59.1 0.7 3.9 4 1 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KEY74332.1 - 0.0056 16.8 0.0 0.12 12.5 0.0 2.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily BTB PF00651.26 KEY74333.1 - 0.0062 16.5 0.0 0.071 13.0 0.0 2.1 1 1 1 2 2 2 1 BTB/POZ domain Caudo_TAP PF02413.12 KEY74333.1 - 0.094 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein DUF2036 PF09724.4 KEY74334.1 - 3.6e-08 32.9 0.0 4.2e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) RhoGEF PF00621.15 KEY74335.1 - 1.2e-26 93.7 1.9 1.9e-26 93.0 0.0 2.1 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.3 KEY74335.1 - 0.017 14.6 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) WXG100 PF06013.7 KEY74335.1 - 0.048 13.6 0.6 0.41 10.6 0.1 2.7 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Phi-29_GP16_7 PF06720.6 KEY74335.1 - 0.082 12.5 0.0 0.3 10.7 0.0 1.9 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 Seryl_tRNA_N PF02403.17 KEY74335.1 - 4.6 7.3 13.3 2.5 8.1 4.8 2.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HORMA PF02301.13 KEY74336.1 - 1.1e-22 80.6 0.0 1.4e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 HORMA domain PI31_Prot_N PF11566.3 KEY74337.1 - 2.5e-25 88.8 0.0 3.1e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 KEY74337.1 - 3.8e-16 59.4 18.4 3.8e-16 59.4 12.8 2.6 3 1 0 3 3 3 1 PI31 proteasome regulator IBN_N PF03810.14 KEY74338.1 - 5.4e-10 39.0 1.9 3.3e-09 36.5 0.1 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KEY74338.1 - 0.00025 20.9 0.3 0.004 17.0 0.0 3.0 3 0 0 3 3 3 1 Exportin 1-like protein CAS_CSE1 PF03378.10 KEY74338.1 - 0.0067 14.7 0.0 0.012 13.9 0.0 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus T_cell_tran_alt PF15128.1 KEY74339.1 - 0.032 13.6 0.1 0.081 12.3 0.1 1.6 1 0 0 1 1 1 0 T-cell leukemia translocation-altered TraP PF07296.6 KEY74339.1 - 4.1 6.3 8.5 0.22 10.4 2.1 1.6 2 0 0 2 2 2 0 TraP protein Transp_cyt_pur PF02133.10 KEY74340.1 - 1.7e-152 508.0 35.1 2e-152 507.8 24.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans_2 PF11951.3 KEY74341.1 - 4.3e-29 101.2 0.0 5.6e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY74341.1 - 5.7e-06 26.1 9.0 1e-05 25.3 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3129 PF11327.3 KEY74342.1 - 5.2e-67 225.2 13.0 7.9e-67 224.6 9.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Metallophos PF00149.23 KEY74344.1 - 4.3e-42 143.7 0.7 5.2e-42 143.5 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rho_GDI PF02115.12 KEY74345.1 - 9.3e-60 201.4 0.3 1e-59 201.3 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor E1_DerP2_DerF2 PF02221.10 KEY74345.1 - 0.14 12.3 0.1 0.24 11.6 0.0 1.5 1 1 0 1 1 1 0 ML domain Kelch_5 PF13854.1 KEY74346.1 - 4.3e-08 32.9 13.4 1.5e-07 31.2 0.2 4.7 4 1 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 KEY74346.1 - 0.016 14.9 1.7 12 5.8 0.0 4.2 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 KEY74346.1 - 0.036 13.8 12.8 0.049 13.4 0.1 4.7 4 1 1 5 5 5 0 Galactose oxidase, central domain Herpes_gE PF02480.11 KEY74346.1 - 0.072 11.3 0.0 0.1 10.8 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Kelch_6 PF13964.1 KEY74346.1 - 0.32 11.2 7.7 6.6 7.0 0.0 4.3 5 0 0 5 5 5 0 Kelch motif Glyco_hydro_3 PF00933.16 KEY74347.1 - 4.8e-68 229.3 0.0 2.4e-67 227.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY74347.1 - 1.2e-34 119.8 0.5 1.7e-33 116.0 0.0 2.5 3 0 0 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEY74347.1 - 3.1e-22 78.3 0.0 7.2e-22 77.1 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Epimerase PF01370.16 KEY74348.1 - 8.2e-14 51.6 0.1 2.2e-10 40.3 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY74348.1 - 7.8e-05 22.7 0.1 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEY74348.1 - 0.00011 20.9 0.1 0.00047 18.9 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KEY74348.1 - 0.00088 18.2 0.0 0.0016 17.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KEY74348.1 - 0.017 14.4 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family F-box PF00646.28 KEY74355.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 F-box domain DUF3435 PF11917.3 KEY74357.1 - 7.4e-55 186.3 0.0 1e-54 185.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) GATA PF00320.22 KEY74359.1 - 0.082 12.2 0.2 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 GATA zinc finger Glyco_hydro_61 PF03443.9 KEY74360.1 - 3.5e-33 115.2 0.1 4e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Peptidase_S8 PF00082.17 KEY74362.1 - 0.0031 16.7 0.0 0.0031 16.7 0.0 1.1 1 0 0 1 1 1 1 Subtilase family Asparaginase PF00710.15 KEY74363.1 - 2.8e-41 141.4 0.0 3.3e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Peptidase_C2 PF00648.16 KEY74364.1 - 3.2e-14 52.6 0.0 5.3e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Peptidase_C1 PF00112.18 KEY74364.1 - 0.03 14.1 0.1 0.046 13.5 0.1 1.2 1 0 0 1 1 1 0 Papain family cysteine protease Ank_2 PF12796.2 KEY74365.1 - 6.7e-32 109.6 0.8 3e-15 56.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEY74365.1 - 2.4e-24 83.8 0.8 0.00014 21.5 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KEY74365.1 - 5e-24 84.2 0.0 1.2e-09 38.4 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY74365.1 - 2.7e-23 79.6 0.2 0.00027 20.8 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KEY74365.1 - 6.5e-18 64.3 0.3 4.5e-06 26.7 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Fructosamin_kin PF03881.9 KEY74365.1 - 0.014 14.3 0.1 0.039 12.9 0.1 1.6 2 0 0 2 2 2 0 Fructosamine kinase WEMBL PF05701.6 KEY74366.1 - 0.017 13.6 2.0 0.02 13.3 1.4 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light SlyX PF04102.7 KEY74366.1 - 0.06 13.7 0.9 0.17 12.2 0.6 1.7 1 0 0 1 1 1 0 SlyX DUF87 PF01935.12 KEY74366.1 - 0.079 12.7 0.3 0.1 12.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 Bacillus_HBL PF05791.6 KEY74366.1 - 0.13 11.6 0.2 0.18 11.1 0.2 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) FAD_binding_3 PF01494.14 KEY74368.1 - 1.2e-09 37.7 0.0 1.3e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.20 KEY74369.1 - 0.0011 18.9 0.1 0.0021 18.0 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY74370.1 - 1.1e-10 41.7 0.0 2.1e-10 40.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEY74370.1 - 6.7e-10 39.1 1.3 2.5e-08 34.0 0.9 2.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY74370.1 - 0.064 12.9 0.2 0.36 10.4 0.0 2.3 2 1 0 2 2 2 0 KR domain Transferase PF02458.10 KEY74372.1 - 1.1e-07 30.6 0.0 1.2e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 Transferase family LIP PF03583.9 KEY74373.1 - 1.5e-63 214.7 0.0 1.9e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_1 PF00561.15 KEY74373.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold FAD_binding_3 PF01494.14 KEY74374.1 - 3.9e-18 65.6 7.5 1.1e-16 60.8 5.2 2.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEY74374.1 - 3.5e-09 36.0 0.6 2e-08 33.5 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEY74374.1 - 0.00021 21.6 1.9 0.00047 20.4 1.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY74374.1 - 0.00026 20.9 0.7 0.00072 19.5 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KEY74374.1 - 0.009 15.9 0.1 0.016 15.0 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KEY74374.1 - 0.012 15.2 0.3 0.021 14.4 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KEY74374.1 - 0.035 13.8 0.1 0.065 12.9 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.1 KEY74374.1 - 0.037 14.0 0.1 0.084 12.9 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 KEY74374.1 - 0.08 12.7 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KEY74374.1 - 0.12 12.8 0.3 0.26 11.7 0.2 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ketoacyl-synt PF00109.21 KEY74375.1 - 4.4e-65 219.6 0.9 1e-64 218.4 0.6 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEY74375.1 - 8.3e-31 107.4 0.1 2.9e-28 99.1 0.0 2.3 2 0 0 2 2 2 2 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KEY74375.1 - 1.8e-29 101.9 0.0 6.4e-29 100.2 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KEY74375.1 - 2.5e-29 101.9 0.0 4.1e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 KEY74375.1 - 4.5e-12 46.3 0.0 1.4e-11 44.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KEY74375.1 - 9e-12 45.0 0.5 3e-11 43.4 0.3 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 KEY74375.1 - 2.5e-10 40.2 0.0 3.3e-09 36.6 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY74375.1 - 4.1e-08 32.9 0.0 8.6e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY74375.1 - 6.9e-07 29.6 0.0 2.4e-06 27.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY74375.1 - 2.8e-06 27.8 0.0 1.1e-05 25.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 KEY74375.1 - 1.1e-05 24.9 0.0 2.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.1 KEY74375.1 - 3.9e-05 23.9 0.0 0.00036 20.8 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.20 KEY74375.1 - 0.00022 21.1 0.0 0.00099 19.0 0.0 2.3 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.18 KEY74375.1 - 0.00069 18.6 0.0 0.0015 17.5 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_26 PF13659.1 KEY74375.1 - 0.0078 16.2 0.0 0.036 14.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KEY74375.1 - 0.0088 15.7 0.0 0.029 14.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 KEY74375.1 - 0.049 12.5 0.0 0.097 11.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1638 PF07796.6 KEY74376.1 - 0.047 13.3 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1638) Ank_2 PF12796.2 KEY74377.1 - 2.6e-74 245.5 7.1 1.8e-10 41.0 0.0 11.7 3 2 8 12 12 12 11 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEY74377.1 - 1.1e-51 172.3 8.1 1.4e-06 28.6 0.0 14.5 12 3 3 15 15 15 12 Ankyrin repeats (many copies) Ank PF00023.25 KEY74377.1 - 4.5e-45 149.2 28.9 9.7e-06 25.1 0.0 18.2 20 0 0 20 20 20 12 Ankyrin repeat Ank_5 PF13857.1 KEY74377.1 - 1.1e-44 149.3 19.8 2.6e-06 27.4 0.4 15.4 9 4 8 17 17 17 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY74377.1 - 2.2e-31 104.7 14.7 0.19 12.0 0.0 17.8 18 0 0 18 18 18 7 Ankyrin repeat Peptidase_S8 PF00082.17 KEY74378.1 - 3.5e-15 55.9 0.0 5.9e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Ank PF00023.25 KEY74378.1 - 0.051 13.3 0.1 6.9 6.6 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat Abhydrolase_6 PF12697.2 KEY74380.1 - 9.3e-06 25.6 0.1 1.1e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY74380.1 - 0.0012 18.6 0.0 0.0014 18.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 KEY74380.1 - 0.1 11.3 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 Chlorophyllase LIP PF03583.9 KEY74380.1 - 0.15 11.2 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Secretory lipase NmrA PF05368.8 KEY74381.1 - 7.2e-19 67.9 0.2 4.7e-18 65.2 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family DUF1914 PF08932.5 KEY74381.1 - 0.0042 17.1 0.2 0.0082 16.1 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1914) 3Beta_HSD PF01073.14 KEY74381.1 - 0.0053 15.4 0.1 0.06 12.0 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ABC2_membrane PF01061.19 KEY74382.1 - 1.2e-88 295.7 39.7 2.6e-46 157.4 10.9 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 KEY74382.1 - 9e-38 129.6 0.0 2.9e-18 66.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KEY74382.1 - 1.8e-28 98.2 0.2 1.1e-23 82.8 0.0 2.6 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 KEY74382.1 - 1.5e-18 66.9 28.5 3.5e-10 39.4 7.0 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 KEY74382.1 - 1.1e-07 31.8 0.0 3.4e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KEY74382.1 - 1.6e-05 24.4 0.0 0.02 14.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEY74382.1 - 5.3e-05 23.2 0.6 0.01 15.8 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEY74382.1 - 0.00018 21.6 0.1 0.16 12.1 0.0 3.3 3 1 0 3 3 3 1 AAA domain DUF258 PF03193.11 KEY74382.1 - 0.00033 19.8 0.1 0.0053 15.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KEY74382.1 - 0.00062 19.2 0.1 0.053 13.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 KEY74382.1 - 0.00099 19.0 1.3 0.082 12.8 0.3 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KEY74382.1 - 0.0017 17.8 1.3 0.59 9.5 0.2 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 KEY74382.1 - 0.0018 18.5 0.1 0.85 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KEY74382.1 - 0.0053 16.6 0.0 0.9 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEY74382.1 - 0.01 15.5 1.1 4.1 7.2 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_17 PF13207.1 KEY74382.1 - 0.013 16.3 0.0 0.83 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KEY74382.1 - 0.013 14.9 0.9 1.3 8.4 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 KEY74382.1 - 0.021 14.4 0.0 2.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 KEY74382.1 - 0.022 14.3 0.4 1.8 8.1 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.1 KEY74382.1 - 0.024 14.6 0.1 0.47 10.3 0.0 2.9 4 0 0 4 4 4 0 AAA domain Miro PF08477.8 KEY74382.1 - 0.08 13.4 0.0 6.3 7.3 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Zn_clus PF00172.13 KEY74383.1 - 4.8e-05 23.1 11.5 0.0001 22.1 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.12 KEY74383.1 - 3.4 6.3 4.8 5.2 5.7 3.3 1.2 1 0 0 1 1 1 0 Clusterin HypA PF01155.14 KEY74383.1 - 4 7.1 5.2 20 4.8 3.1 2.1 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family NmrA PF05368.8 KEY74384.1 - 6.1e-22 78.0 0.0 7.1e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY74384.1 - 1.4e-12 48.0 0.0 2.6e-12 47.1 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEY74384.1 - 5.6e-05 22.6 0.0 0.00023 20.6 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEY74384.1 - 0.00036 19.3 0.1 0.0016 17.2 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Formyl_trans_N PF00551.14 KEY74384.1 - 0.0054 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase Lactamase_B_2 PF12706.2 KEY74384.1 - 0.082 12.4 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain NmrA PF05368.8 KEY74385.1 - 9.3e-36 123.2 0.0 2.6e-35 121.7 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY74385.1 - 2.7e-09 37.2 0.0 3.9e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 KEY74385.1 - 0.0099 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Semialdhyde_dh PF01118.19 KEY74385.1 - 0.08 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KEY74385.1 - 0.21 10.2 0.0 0.34 9.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF4267 PF14087.1 KEY74386.1 - 2e-14 53.1 4.1 2.5e-14 52.8 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF3681 PF12442.3 KEY74386.1 - 0.41 10.8 8.9 1.9 8.6 6.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3681) adh_short PF00106.20 KEY74387.1 - 8.2e-14 51.8 1.5 9.9e-14 51.5 0.2 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY74387.1 - 2.2e-06 27.6 0.0 2.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY74387.1 - 0.00095 18.8 0.4 0.0018 17.9 0.3 1.4 1 0 0 1 1 1 1 KR domain Fungal_trans_2 PF11951.3 KEY74388.1 - 1.4e-32 112.7 0.2 1.9e-32 112.2 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain CDC14 PF08045.6 KEY74388.1 - 0.14 11.2 0.1 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Cell division control protein 14, SIN component MFS_1 PF07690.11 KEY74389.1 - 2e-30 105.7 35.1 2.8e-30 105.2 24.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KEY74390.1 - 3.8e-42 144.2 0.3 4.7e-42 143.9 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain PhyH PF05721.8 KEY74391.1 - 2.6e-05 24.3 0.1 3.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KEY74391.1 - 0.0029 16.1 0.0 0.024 13.1 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1479) Pkinase PF00069.20 KEY74392.1 - 1.8e-27 96.1 0.0 4e-15 55.6 0.0 2.5 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEY74392.1 - 1.9e-08 33.6 0.0 0.0078 15.3 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KEY74392.1 - 0.0042 16.8 0.0 0.0085 15.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KEY74392.1 - 0.0088 15.1 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KEY74392.1 - 0.16 10.9 0.0 1.3 7.9 0.0 2.0 2 0 0 2 2 2 0 Kinase-like HET PF06985.6 KEY74393.1 - 4.3e-26 91.7 0.0 8e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GST_N_3 PF13417.1 KEY74394.1 - 5.3e-15 55.3 0.0 1.3e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KEY74394.1 - 9.9e-14 51.2 0.0 2.2e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEY74394.1 - 6.1e-13 48.5 0.0 2.1e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Fungal_trans_2 PF11951.3 KEY74395.1 - 6.5e-05 21.7 0.1 9.8e-05 21.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Herpes_UL1 PF05259.6 KEY74395.1 - 0.11 11.8 0.0 14 5.1 0.0 2.4 2 0 0 2 2 2 0 Herpesvirus glycoprotein L Ank_5 PF13857.1 KEY74396.1 - 0.029 14.6 0.0 2.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEY74396.1 - 0.036 14.5 0.0 11 6.6 0.0 2.3 2 1 0 2 2 2 0 Ankyrin repeats (many copies) HET PF06985.6 KEY74398.1 - 2.1e-22 79.7 6.9 5.5e-19 68.7 0.1 3.0 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) M3 PF09213.5 KEY74398.1 - 0.16 10.4 0.0 0.26 9.7 0.0 1.3 1 0 0 1 1 1 0 M3 adh_short PF00106.20 KEY74399.1 - 5.9e-15 55.5 0.1 1.3e-14 54.5 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY74399.1 - 4.4e-08 32.9 0.0 6.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 KR domain OPT PF03169.10 KEY74400.1 - 1.1e-120 404.0 48.0 1.2e-120 403.8 33.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FAD_binding_4 PF01565.18 KEY74401.1 - 1.8e-15 56.6 1.3 1.1e-14 54.1 0.9 2.1 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY74401.1 - 1.4e-05 24.9 0.1 1.4e-05 24.9 0.1 2.2 2 0 0 2 2 2 1 Berberine and berberine like Pectate_lyase PF03211.8 KEY74402.1 - 1.5e-82 276.1 5.3 1.7e-82 275.9 3.7 1.0 1 0 0 1 1 1 1 Pectate lyase Glyco_hydro_61 PF03443.9 KEY74403.1 - 9.2e-48 162.9 0.0 1.1e-47 162.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 A2M_N PF01835.14 KEY74403.1 - 0.0035 17.5 0.0 0.0099 16.1 0.0 1.9 1 1 0 1 1 1 1 MG2 domain He_PIG PF05345.7 KEY74403.1 - 0.11 12.5 2.8 4.1 7.5 0.0 3.5 3 0 0 3 3 3 0 Putative Ig domain MFS_1 PF07690.11 KEY74405.1 - 0.085 11.5 47.7 0.018 13.8 15.8 3.2 1 1 1 2 2 2 0 Major Facilitator Superfamily Metallothio_Pro PF02069.11 KEY74407.1 - 0.01 15.6 0.2 0.012 15.4 0.1 1.1 1 0 0 1 1 1 0 Prokaryotic metallothionein DDE_Tnp_1_7 PF13843.1 KEY74408.1 - 1.4e-16 60.5 0.0 2.5e-16 59.7 0.0 1.4 1 1 0 1 1 1 1 Transposase IS4 Golgin_A5 PF09787.4 KEY74409.1 - 0.021 13.3 0.6 0.029 12.9 0.0 1.4 2 0 0 2 2 2 0 Golgin subfamily A member 5 PEP-utilisers_N PF05524.8 KEY74409.1 - 0.16 11.8 1.5 1.1 9.1 0.1 2.2 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Co_AT_N PF12557.3 KEY74409.1 - 1.6 8.7 4.3 1.4 8.9 1.3 2.1 2 0 0 2 2 2 0 Cob(I)alamin adenosyltransferase N terminal rve PF00665.21 KEY74410.1 - 3.3e-14 53.0 0.0 9.1e-14 51.6 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain EntA_Immun PF08951.5 KEY74410.1 - 2.2 8.4 4.6 7.3 6.8 0.4 2.3 1 1 1 2 2 2 0 Enterocin A Immunity Pectate_lyase PF03211.8 KEY74411.1 - 1.1e-61 207.9 4.4 1.3e-61 207.7 3.1 1.0 1 0 0 1 1 1 1 Pectate lyase HET PF06985.6 KEY74412.1 - 3.9e-30 104.8 0.2 7.5e-29 100.6 0.2 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_61 PF03443.9 KEY74413.1 - 1.2e-08 35.0 0.0 1.3e-08 34.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HAUS2 PF15003.1 KEY74414.1 - 0.0078 15.3 1.0 0.013 14.5 0.0 1.8 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 2 SpoVIF PF14069.1 KEY74414.1 - 0.1 12.3 0.2 0.29 10.8 0.1 1.9 1 0 0 1 1 1 0 Stage VI sporulation protein F YscO PF07321.7 KEY74414.1 - 0.24 11.2 6.8 0.047 13.5 1.8 1.9 2 0 0 2 2 2 0 Type III secretion protein YscO DMPK_coil PF08826.5 KEY74414.1 - 0.96 9.3 5.4 1.1 9.2 0.1 3.0 3 0 0 3 3 3 0 DMPK coiled coil domain like WSC PF01822.14 KEY74417.1 - 8.7e-10 38.3 2.7 8.7e-10 38.3 1.9 2.1 3 0 0 3 3 3 1 WSC domain Ribonuc_L-PSP PF01042.16 KEY74418.1 - 1.3e-17 63.7 0.0 2.2e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP Glyco_hydro_3 PF00933.16 KEY74419.1 - 1e-70 238.0 0.0 6.1e-64 215.8 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY74419.1 - 2.9e-38 131.6 0.4 3.5e-37 128.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEY74419.1 - 2e-24 85.2 0.1 3.8e-24 84.4 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3425 PF11905.3 KEY74420.1 - 2.1e-29 102.1 0.5 4.4e-29 101.1 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Aldo_ket_red PF00248.16 KEY74421.1 - 4.2e-57 193.1 0.0 7.4e-57 192.3 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.20 KEY74422.1 - 1.7e-17 63.8 0.1 2.5e-17 63.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY74422.1 - 2.1e-06 27.5 0.1 3.7e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY74422.1 - 9.3e-06 25.5 0.0 1.3e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEY74422.1 - 0.0074 15.7 0.0 0.016 14.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY74422.1 - 0.035 14.1 0.1 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 NADH(P)-binding DUF2701 PF10857.3 KEY74422.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2701) p450 PF00067.17 KEY74423.1 - 7.8e-18 64.2 0.0 2e-17 62.8 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KEY74424.1 - 3e-87 293.0 0.0 3e-66 223.8 0.0 2.2 1 1 1 2 2 2 2 Cytochrome P450 ADH_zinc_N_2 PF13602.1 KEY74425.1 - 3.7e-11 44.0 0.1 1.1e-10 42.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KEY74425.1 - 5.5e-10 38.8 0.0 1.1e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Cupin_2 PF07883.6 KEY74426.1 - 6.5e-09 35.1 0.0 1.2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 KEY74426.1 - 0.0014 17.9 0.0 0.0025 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Glyco_hydro_61 PF03443.9 KEY74428.1 - 1.4e-52 178.6 0.0 1.8e-52 178.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF2263 PF10021.4 KEY74429.1 - 2.8e-19 69.5 0.0 5.2e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.16 KEY74429.1 - 0.057 13.3 0.0 8.5 6.3 0.0 2.6 2 0 0 2 2 2 0 Macro domain SMI1_KNR4 PF09346.5 KEY74432.1 - 7.9e-06 25.9 0.0 1.9e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.1 KEY74432.1 - 5.1e-05 23.7 0.0 0.00012 22.5 0.0 1.7 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall SUKH_5 PF14567.1 KEY74432.1 - 0.0014 18.1 0.0 0.0046 16.4 0.0 1.8 2 0 0 2 2 2 1 SMI1-KNR4 cell-wall FA_desaturase PF00487.19 KEY74433.1 - 1.1 8.6 4.6 1.9 7.8 3.2 1.4 1 0 0 1 1 1 0 Fatty acid desaturase MFS_1 PF07690.11 KEY74434.1 - 2.2e-10 39.8 7.9 2.5e-10 39.5 5.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY74434.1 - 0.00021 20.0 2.0 0.00029 19.5 1.3 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY74435.1 - 7.5e-26 90.6 9.9 7.5e-26 90.6 6.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KEY74435.1 - 0.014 13.6 1.6 0.016 13.3 0.1 1.8 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) HET PF06985.6 KEY74436.1 - 2.6e-37 128.0 0.7 2.6e-37 128.0 0.5 1.6 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 KEY74437.1 - 3.4e-06 26.8 0.1 8e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEY74437.1 - 0.002 18.1 0.0 0.0056 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain PQQ_2 PF13360.1 KEY74437.1 - 0.12 11.8 0.0 1.4 8.3 0.0 2.7 3 0 0 3 3 3 0 PQQ-like domain FAD-oxidase_C PF02913.14 KEY74438.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain Abi PF02517.11 KEY74438.1 - 0.84 9.8 6.7 1.4 9.1 0.1 3.1 3 0 0 3 3 3 0 CAAX protease self-immunity Abhydrolase_3 PF07859.8 KEY74439.1 - 3.6e-45 154.1 0.0 4.6e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KEY74439.1 - 1.8e-13 50.0 2.0 9e-13 47.7 1.4 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 KEY74439.1 - 0.00034 20.5 0.1 0.00053 19.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY74439.1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEY74439.1 - 0.14 11.3 0.3 3 7.0 0.2 2.6 2 1 0 2 2 2 0 Prolyl oligopeptidase family HhH-GPD PF00730.20 KEY74441.1 - 1.5e-12 47.7 0.1 3.2e-12 46.6 0.0 1.6 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein adh_short PF00106.20 KEY74442.1 - 3.5e-06 27.0 0.0 5.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KEY74442.1 - 5.1e-05 22.8 0.0 7.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KEY74442.1 - 0.0036 16.9 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 KR domain p450 PF00067.17 KEY74443.1 - 1.3e-59 202.0 0.0 1.5e-59 201.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 KEY74444.1 - 2.4e-23 82.3 0.1 4.5e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY74444.1 - 6.2e-06 26.0 11.1 1.1e-05 25.1 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydantoinase_B PF02538.9 KEY74445.1 - 3.1e-192 639.4 0.0 4.2e-192 639.0 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KEY74445.1 - 2e-93 312.6 0.0 4.3e-93 311.5 0.0 1.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KEY74445.1 - 2.8e-54 183.2 1.4 1.3e-52 177.8 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.11 KEY74446.1 - 3.8e-35 121.2 30.2 5.5e-35 120.7 21.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily tRNA-synt_1d PF00750.14 KEY74447.1 - 7.4e-50 169.7 0.1 9.7e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KEY74447.1 - 1.1e-08 35.0 0.7 1.6e-07 31.2 0.0 2.6 2 1 0 2 2 2 1 DALR anticodon binding domain FIVAR PF07554.8 KEY74449.1 - 0.077 13.2 0.3 0.22 11.7 0.2 1.7 2 0 0 2 2 2 0 Uncharacterised Sugar-binding Domain APH PF01636.18 KEY74450.1 - 9.2e-14 51.7 0.0 2.4e-13 50.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEY74450.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Alk_phosphatase PF00245.15 KEY74451.1 - 4.9e-82 275.8 0.0 6.2e-82 275.5 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Glyco_hydro_61 PF03443.9 KEY74452.1 - 2.5e-71 239.9 0.0 2.8e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 adh_short PF00106.20 KEY74454.1 - 2.7e-26 92.4 5.9 9.9e-26 90.6 4.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY74454.1 - 2.6e-14 53.2 2.4 4e-14 52.6 1.7 1.3 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY74454.1 - 2.9e-10 40.3 0.3 6.4e-10 39.2 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEY74454.1 - 3.8e-09 36.3 0.1 5e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KEY74454.1 - 7e-06 25.4 0.7 9.8e-06 24.9 0.5 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY74454.1 - 1e-05 25.6 0.4 2.9e-05 24.1 0.3 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEY74454.1 - 0.0017 17.1 0.2 0.0039 15.9 0.2 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KEY74454.1 - 0.0021 17.0 0.1 0.0026 16.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KEY74454.1 - 0.0025 16.7 0.4 0.0039 16.1 0.3 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KEY74454.1 - 0.015 14.2 1.3 0.12 11.3 0.9 2.1 1 1 0 1 1 1 0 Male sterility protein Eno-Rase_NADH_b PF12242.3 KEY74454.1 - 0.089 12.5 1.8 0.22 11.3 0.6 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase YjeF_N PF03853.10 KEY74454.1 - 0.24 10.9 2.8 0.75 9.3 0.1 2.1 1 1 1 2 2 2 0 YjeF-related protein N-terminus Saccharop_dh PF03435.13 KEY74455.1 - 1.7e-17 63.4 0.3 2.3e-17 63.0 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KEY74455.1 - 5.3e-06 26.5 0.0 1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 KEY74455.1 - 0.038 14.1 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 KEY74456.1 - 1.8e-12 47.4 0.3 7.9e-08 32.3 0.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase adh_short PF00106.20 KEY74458.1 - 3.7e-20 72.5 0.0 5.3e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY74458.1 - 5.1e-11 42.7 0.0 8.3e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY74458.1 - 2.9e-06 27.0 0.0 4.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KEY74458.1 - 0.00025 20.3 0.0 0.00098 18.3 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 KEY74458.1 - 0.00025 20.5 0.0 0.075 12.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY74458.1 - 0.00037 20.5 0.0 0.0023 17.9 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KEY74458.1 - 0.025 14.3 0.1 0.061 13.1 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ecl1 PF12855.2 KEY74459.1 - 0.0044 16.2 0.1 0.011 14.9 0.0 1.6 1 0 0 1 1 1 1 Life-span regulatory factor DUF2256 PF10013.4 KEY74459.1 - 0.25 11.1 5.7 1.7 8.4 3.9 2.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Bd3614_N PF14442.1 KEY74459.1 - 3.4 7.6 6.1 10 6.0 0.2 2.8 2 1 1 3 3 3 0 Bd3614-like deaminase N-terminal FhuF_C PF11575.3 KEY74459.1 - 7.8 6.2 8.1 0.68 9.6 2.0 2.0 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain CMAS PF02353.15 KEY74460.1 - 9.6e-58 195.4 0.3 1.2e-57 195.1 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KEY74460.1 - 1.8e-11 43.9 0.0 3.4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY74460.1 - 1e-06 29.0 0.0 2.2e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY74460.1 - 5.1e-06 27.0 0.0 1.1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY74460.1 - 1e-05 24.9 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KEY74460.1 - 2.5e-05 24.2 0.0 0.00066 19.6 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 KEY74460.1 - 0.00013 21.3 0.0 0.00021 20.6 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.1 KEY74460.1 - 0.00018 21.1 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY74460.1 - 0.00036 20.8 0.0 0.00083 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KEY74460.1 - 0.0015 18.1 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 KEY74460.1 - 0.011 16.1 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF1418 PF07214.7 KEY74460.1 - 0.088 12.4 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) PrmA PF06325.8 KEY74460.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Alk_phosphatase PF00245.15 KEY74461.1 - 6.7e-76 255.6 0.0 8.7e-76 255.2 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Acetyltransf_1 PF00583.19 KEY74462.1 - 4.6e-10 39.3 0.0 6.9e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEY74462.1 - 1.2e-05 25.3 0.0 1.9e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEY74462.1 - 5.9e-05 22.9 0.1 0.055 13.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEY74462.1 - 0.0053 16.8 0.1 0.0098 16.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KEY74462.1 - 0.07 13.0 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEY74462.1 - 0.11 12.2 0.1 0.33 10.7 0.0 1.9 2 1 0 2 2 2 0 FR47-like protein DUF86 PF01934.12 KEY74464.1 - 0.44 10.1 0.0 0.74 9.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF86 PA14_2 PF10528.4 KEY74465.1 - 4.3e-18 65.3 0.0 7.2e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 GLEYA domain Peptidase_S8 PF00082.17 KEY74466.1 - 4.8e-48 163.7 0.4 7.4e-48 163.1 0.3 1.3 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 KEY74466.1 - 1.6e-05 25.2 0.0 3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 KEY74466.1 - 0.0064 16.1 0.0 0.019 14.6 0.0 1.8 1 0 0 1 1 1 1 PA domain Abhydrolase_6 PF12697.2 KEY74467.1 - 6e-18 65.5 0.0 7.7e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY74467.1 - 3.5e-07 30.0 0.0 5.9e-07 29.2 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY74467.1 - 9.5e-07 28.6 0.0 1.4e-06 28.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 KEY74467.1 - 0.00021 21.0 0.1 0.00051 19.8 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) CFEM PF05730.6 KEY74468.1 - 0.00065 19.4 3.4 0.0016 18.2 2.3 1.7 1 0 0 1 1 1 1 CFEM domain Aminotran_5 PF00266.14 KEY74469.1 - 1e-58 198.9 0.0 1.2e-58 198.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KEY74469.1 - 5.3e-06 25.6 0.0 9.6e-06 24.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KEY74469.1 - 0.00017 20.0 0.0 0.00027 19.3 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pkinase PF00069.20 KEY74470.1 - 2.6e-27 95.5 0.0 8.4e-27 93.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY74470.1 - 7.4e-08 31.7 0.0 0.15 11.0 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.18 KEY74470.1 - 0.007 16.1 0.1 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pro_Al_protease PF02983.9 KEY74471.1 - 6.5e-05 22.8 0.3 6.5e-05 22.8 0.2 2.7 2 1 0 2 2 2 1 Alpha-lytic protease prodomain HTH_AsnC-type PF13404.1 KEY74471.1 - 0.056 13.0 0.8 2.3 7.8 0.0 3.1 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain GMC_oxred_C PF05199.8 KEY74472.1 - 5.5e-05 23.4 0.1 8.2e-05 22.9 0.1 1.3 1 1 0 1 1 1 1 GMC oxidoreductase adh_short PF00106.20 KEY74473.1 - 2.9e-16 59.8 0.1 7e-16 58.5 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY74473.1 - 2.6e-10 40.2 0.2 5.9e-10 39.1 0.1 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY74473.1 - 1.9e-07 31.0 0.0 2.9e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEY74473.1 - 0.002 17.5 0.6 0.0062 16.0 0.4 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TIR-like PF10137.4 KEY74473.1 - 0.0022 17.6 0.0 0.0049 16.4 0.0 1.6 1 0 0 1 1 1 1 Predicted nucleotide-binding protein containing TIR-like domain ApbA PF02558.11 KEY74473.1 - 0.063 12.7 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA YjeF_N PF03853.10 KEY74473.1 - 0.067 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus NAD_binding_10 PF13460.1 KEY74473.1 - 0.087 12.8 0.1 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding DUF3425 PF11905.3 KEY74474.1 - 4.2e-28 97.9 0.3 6.9e-28 97.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Sulfotransfer_3 PF13469.1 KEY74475.1 - 0.11 13.3 0.9 0.24 12.2 0.6 1.6 1 1 0 1 1 1 0 Sulfotransferase family Kelch_6 PF13964.1 KEY74476.1 - 9.6e-28 95.1 12.3 7.9e-08 32.1 0.1 6.7 1 1 5 6 6 6 5 Kelch motif Kelch_1 PF01344.20 KEY74476.1 - 1.2e-25 88.8 15.3 8.5e-08 31.6 0.0 7.2 6 2 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 KEY74476.1 - 3.7e-25 87.4 20.8 2.2e-06 27.3 0.1 6.4 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 KEY74476.1 - 4e-21 74.6 13.9 0.00014 21.9 0.2 5.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KEY74476.1 - 1.2e-14 53.8 9.4 0.013 15.4 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 KEY74476.1 - 5.4e-12 44.9 13.5 0.001 18.7 0.0 7.0 6 2 0 6 6 6 3 Kelch motif DUF4453 PF14627.1 KEY74476.1 - 0.015 15.4 0.0 0.099 12.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4453) LysM PF01476.15 KEY74479.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 LysM domain LysM PF01476.15 KEY74481.1 - 5.4e-07 29.4 0.0 0.016 15.0 0.0 3.8 3 0 0 3 3 3 2 LysM domain Transferase PF02458.10 KEY74481.1 - 6.2e-07 28.2 0.0 1.7e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Transferase family GSDH PF07995.6 KEY74481.1 - 0.17 10.9 0.0 3.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Glucose / Sorbosone dehydrogenase AAL_decarboxy PF03306.8 KEY74482.1 - 2.9e-59 199.7 0.0 3.5e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase TPP_enzyme_N PF02776.13 KEY74483.1 - 1.1e-26 93.4 0.7 2.8e-24 85.5 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KEY74483.1 - 1.8e-24 86.0 0.3 3.8e-24 85.0 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KEY74483.1 - 7.4e-20 71.1 0.0 2.9e-19 69.2 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain LptE PF04390.7 KEY74484.1 - 1.8 8.3 7.2 1.8 8.3 0.8 2.3 2 0 0 2 2 2 0 Lipopolysaccharide-assembly MAPEG PF01124.13 KEY74485.1 - 3.6e-13 49.2 3.7 4.8e-13 48.8 2.6 1.3 1 1 0 1 1 1 1 MAPEG family TOMM6 PF15184.1 KEY74485.1 - 0.74 9.1 3.0 2.1 7.7 0.0 2.9 3 1 1 4 4 4 0 Mitochondrial import receptor subunit TOM6 homolog AATase PF07247.7 KEY74486.1 - 5.7e-07 28.4 0.0 3.7e-06 25.7 0.0 2.2 2 1 0 2 2 2 1 Alcohol acetyltransferase LVIVD PF08309.6 KEY74488.1 - 2.5e-09 35.9 0.1 0.015 14.2 0.0 4.0 4 0 0 4 4 4 3 LVIVD repeat Peptidase_S8 PF00082.17 KEY74489.1 - 3.5e-44 151.0 0.5 5.3e-44 150.4 0.3 1.3 1 0 0 1 1 1 1 Subtilase family FlgD_ig PF13860.1 KEY74489.1 - 0.028 14.1 0.0 0.093 12.4 0.0 1.9 1 0 0 1 1 1 0 FlgD Ig-like domain Dimer_Tnp_hAT PF05699.9 KEY74491.1 - 3.1e-20 71.5 0.1 6.6e-20 70.5 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DDE_Tnp_1_7 PF13843.1 KEY74493.1 - 0.0049 15.9 0.0 0.0051 15.9 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 Zn_clus PF00172.13 KEY74494.1 - 0.0024 17.7 5.0 0.0045 16.8 3.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DDE_Tnp_1_7 PF13843.1 KEY74499.1 - 8.6e-22 77.6 0.0 1.7e-20 73.3 0.0 2.0 1 1 1 2 2 2 2 Transposase IS4 RNase_H PF00075.19 KEY74503.1 - 0.036 14.4 0.0 0.04 14.2 0.0 1.0 1 0 0 1 1 1 0 RNase H DDE_1 PF03184.14 KEY74505.1 - 6.2e-34 117.0 0.0 1e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease SOBP PF15279.1 KEY74505.1 - 2.4 8.4 8.0 3.5 7.9 5.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein HET PF06985.6 KEY74507.1 - 4.9e-06 26.7 0.0 7.8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Spo12 PF05032.7 KEY74508.1 - 0.04 13.5 0.1 0.043 13.4 0.0 1.1 1 0 0 1 1 1 0 Spo12 family Peptidase_MA_2 PF13485.1 KEY74509.1 - 0.085 12.8 0.0 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 Peptidase MA superfamily Ank_2 PF12796.2 KEY74510.1 - 3.1e-06 27.4 0.1 3.9e-05 23.9 0.0 2.4 2 2 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEY74510.1 - 4e-05 23.9 0.4 0.0039 17.6 0.0 3.2 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY74510.1 - 0.00028 21.0 0.3 0.0032 17.6 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 KEY74510.1 - 0.00059 19.5 0.2 0.008 15.9 0.0 3.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.1 KEY74510.1 - 0.0044 17.1 0.2 0.035 14.3 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Pectate_lyase_3 PF12708.2 KEY74511.1 - 1.5e-68 231.2 10.8 1.8e-54 185.2 3.0 2.7 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KEY74511.1 - 0.06 12.8 0.6 0.63 9.5 0.1 2.5 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase HET PF06985.6 KEY74512.1 - 2.1e-22 79.7 0.0 8.7e-22 77.7 0.0 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Ammonium_transp PF00909.16 KEY74513.1 - 4.5e-64 216.3 26.9 6e-64 215.9 18.6 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3328 PF11807.3 KEY74513.1 - 1.7e-49 168.4 1.1 2.2e-49 168.0 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) Zip PF02535.17 KEY74514.1 - 2.8 6.8 12.3 2.9 6.8 8.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Flavin_Reduct PF01613.13 KEY74516.1 - 1.2e-19 70.6 0.0 1.7e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Lipocalin_7 PF14651.1 KEY74516.1 - 0.035 13.8 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family E1-E2_ATPase PF00122.15 KEY74517.1 - 3.5e-48 163.6 4.0 9.9e-48 162.1 2.8 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KEY74517.1 - 1.5e-24 87.6 2.0 3.6e-24 86.3 1.4 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KEY74517.1 - 4.7e-12 45.8 1.3 1.9e-10 40.7 0.2 2.6 2 0 0 2 2 2 1 Heavy-metal-associated domain HAD PF12710.2 KEY74517.1 - 6.4e-12 46.0 0.0 1.4e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEY74517.1 - 0.019 14.5 0.5 5.1 6.5 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NCD1 PF04904.8 KEY74518.1 - 0.029 14.1 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) Gemini_AL1 PF00799.15 KEY74518.1 - 0.09 12.6 0.0 2.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Geminivirus Rep catalytic domain Isochorismatase PF00857.15 KEY74519.1 - 1.7e-06 28.1 0.0 2.3e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF3581 PF12119.3 KEY74520.1 - 0.0081 15.4 0.0 0.0094 15.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3581) UPF0262 PF06793.7 KEY74520.1 - 0.014 15.1 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) Chitin_bind_1 PF00187.14 KEY74521.1 - 0.31 11.0 5.8 3 7.8 0.6 3.2 3 0 0 3 3 3 0 Chitin recognition protein Methyltransf_31 PF13847.1 KEY74522.1 - 8.2e-27 93.6 0.2 5e-18 65.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KEY74522.1 - 4.1e-15 56.0 0.0 1.9e-14 53.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY74522.1 - 3.4e-14 52.5 0.1 4.6e-13 48.8 0.1 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEY74522.1 - 5.4e-10 39.5 1.4 1.4e-09 38.2 0.5 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY74522.1 - 3.9e-09 37.0 0.0 8.5e-09 35.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY74522.1 - 2.3e-08 33.9 0.0 3.6e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY74522.1 - 0.00015 22.1 0.4 0.0009 19.6 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 KEY74522.1 - 0.00038 20.1 1.8 0.00055 19.6 0.2 1.9 1 1 1 2 2 2 1 Hypothetical methyltransferase PCMT PF01135.14 KEY74522.1 - 0.00055 19.5 0.2 0.0017 17.9 0.1 1.7 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 KEY74522.1 - 0.0023 17.3 0.6 0.18 11.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain CheR PF01739.13 KEY74522.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Pyr_redox_3 PF13738.1 KEY74523.1 - 1.7e-23 83.7 0.0 2.9e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEY74523.1 - 3.1e-12 45.4 0.1 1.3e-11 43.3 0.0 2.0 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KEY74523.1 - 4.7e-10 38.9 0.0 7e-09 35.0 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KEY74523.1 - 3e-07 30.3 0.1 8.8e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KEY74523.1 - 7.3e-06 25.8 0.1 0.0018 18.0 0.0 3.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KEY74523.1 - 3.4e-05 23.8 0.0 0.00033 20.5 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEY74523.1 - 0.012 14.5 0.1 0.25 10.1 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KEY74523.1 - 0.071 12.1 0.2 2.2 7.2 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Glyco_hydro_11 PF00457.12 KEY74524.1 - 1.1e-74 249.6 26.0 1.4e-74 249.4 18.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 zf-C2H2_jaz PF12171.3 KEY74525.1 - 1e-11 44.6 28.8 0.00069 19.6 0.8 7.3 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEY74525.1 - 9.1e-08 32.0 21.7 8.2e-05 22.6 0.5 7.1 7 0 0 7 7 7 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KEY74525.1 - 1.7e-07 31.0 35.3 0.03 14.6 1.2 7.7 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.21 KEY74525.1 - 6.3e-06 26.2 35.5 0.021 15.1 0.8 7.3 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 KEY74525.1 - 3.5e-05 23.8 20.2 0.011 15.8 0.2 4.9 1 1 4 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 KEY74525.1 - 0.003 17.3 27.8 0.088 12.7 0.4 6.8 7 0 0 7 7 7 3 C2H2-type zinc finger RIG-I_C-RD PF11648.3 KEY74525.1 - 0.022 14.6 0.1 0.052 13.4 0.1 1.6 1 0 0 1 1 1 0 C-terminal domain of RIG-I MFS_1 PF07690.11 KEY74526.1 - 4.3e-42 144.0 46.4 4.3e-42 144.0 32.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY74526.1 - 2.7e-05 22.9 31.6 6.7e-05 21.6 21.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter p450 PF00067.17 KEY74528.1 - 4.2e-13 48.6 0.2 5.7e-10 38.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Zn_clus PF00172.13 KEY74530.1 - 6.5e-10 38.7 7.6 2e-09 37.2 5.3 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY74530.1 - 1.4e-05 24.1 0.1 2.6e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain EndIII_4Fe-2S PF10576.4 KEY74530.1 - 3.4 7.9 7.5 1 9.6 1.6 2.9 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III adh_short PF00106.20 KEY74531.1 - 2.6e-24 86.0 2.3 3.4e-24 85.6 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY74531.1 - 2.2e-13 50.2 0.4 3.1e-13 49.7 0.3 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KEY74531.1 - 0.00032 20.4 0.9 0.00076 19.2 0.3 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KEY74531.1 - 0.00062 19.2 0.0 0.00099 18.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KEY74531.1 - 0.001 18.0 0.0 0.0013 17.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KEY74531.1 - 0.0011 19.0 0.3 0.0023 18.0 0.2 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF3871 PF12987.2 KEY74531.1 - 0.052 12.2 0.0 0.078 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3871) p450 PF00067.17 KEY74532.1 - 1.3e-47 162.3 0.0 1.8e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.8 KEY74533.1 - 0.00025 20.4 0.0 0.00067 18.9 0.0 1.8 2 1 0 2 2 2 1 NmrA-like family Chromo PF00385.19 KEY74534.1 - 4.9e-05 22.9 0.3 0.0013 18.4 0.0 2.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Pkinase PF00069.20 KEY74535.1 - 6.4e-05 22.2 0.3 0.00015 20.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 KEY74535.1 - 0.00087 19.0 0.0 0.00087 19.0 0.0 2.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family SURF6 PF04935.7 KEY74535.1 - 0.0019 17.5 12.3 0.0044 16.3 8.6 1.5 1 0 0 1 1 1 1 Surfeit locus protein 6 Choline_kinase PF01633.15 KEY74535.1 - 0.053 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Herpes_U34 PF04541.8 KEY74535.1 - 0.14 11.0 4.2 0.26 10.1 2.9 1.5 1 0 0 1 1 1 0 Herpesvirus virion protein U34 DUF2828 PF11443.3 KEY74535.1 - 0.15 10.2 1.4 0.25 9.4 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Ycf1 PF05758.7 KEY74535.1 - 0.31 8.7 3.8 0.44 8.2 2.7 1.1 1 0 0 1 1 1 0 Ycf1 Radial_spoke_3 PF06098.6 KEY74535.1 - 0.65 8.9 16.8 1.2 8.0 11.7 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 SRP-alpha_N PF04086.8 KEY74535.1 - 2.6 7.3 16.4 6.4 6.0 6.0 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF342 PF03961.8 KEY74535.1 - 3.1 6.1 3.9 4.6 5.5 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF874 PF05917.6 KEY74535.1 - 6.8 5.4 11.1 10 4.8 7.7 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) HET PF06985.6 KEY74536.1 - 9.5e-31 106.8 0.1 1.6e-30 106.0 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1183 PF06682.7 KEY74537.1 - 0.01 15.5 9.0 0.013 15.1 6.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) SlyX PF04102.7 KEY74538.1 - 0.015 15.6 4.0 0.046 14.1 2.8 1.8 1 0 0 1 1 1 0 SlyX DUF87 PF01935.12 KEY74538.1 - 0.024 14.4 0.5 0.041 13.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 PIN_4 PF13638.1 KEY74538.1 - 0.063 13.3 1.4 0.51 10.4 0.1 2.4 2 0 0 2 2 2 0 PIN domain ATG16 PF08614.6 KEY74538.1 - 0.29 10.9 10.2 0.061 13.1 3.9 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.3 KEY74538.1 - 0.5 10.2 6.4 1.2 8.9 4.4 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 KEY74538.1 - 1.9 8.2 8.1 3.4 7.4 3.3 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein APH PF01636.18 KEY74541.1 - 1.7e-11 44.2 0.0 4.1e-11 43.0 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEY74541.1 - 0.019 14.5 0.0 0.029 13.9 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase HET PF06985.6 KEY74542.1 - 7.7e-32 110.3 1.5 2e-31 108.9 1.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) IU_nuc_hydro PF01156.14 KEY74543.1 - 4.7e-26 91.7 0.0 5.5e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase KRTAP7 PF15034.1 KEY74544.1 - 0.024 15.2 0.1 0.041 14.5 0.0 1.3 1 0 0 1 1 1 0 KRTAP type 7 family Zn_clus PF00172.13 KEY74545.1 - 0.00011 22.0 7.1 0.00021 21.1 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY74545.1 - 0.079 11.8 0.1 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Epimerase PF01370.16 KEY74546.1 - 1.2e-12 47.7 0.0 7.5e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY74546.1 - 1.3e-05 25.3 0.0 2.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KEY74546.1 - 6.5e-05 21.9 0.3 0.0037 16.2 0.1 2.3 1 1 1 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 KEY74546.1 - 0.0022 16.9 0.0 0.0035 16.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KEY74546.1 - 0.015 13.9 0.1 0.026 13.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KEY74546.1 - 0.023 14.9 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 KEY74546.1 - 0.066 12.4 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Ank_4 PF13637.1 KEY74548.1 - 5.2e-24 84.1 0.1 8.1e-10 38.9 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KEY74548.1 - 6.1e-23 79.4 0.0 2.4e-05 23.9 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 KEY74548.1 - 8.5e-23 80.5 0.0 2.2e-11 43.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEY74548.1 - 3.8e-17 61.9 0.0 8.1e-06 25.9 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY74548.1 - 1e-15 56.2 0.0 0.0035 17.4 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat WD40 PF00400.27 KEY74548.1 - 1.4e-14 53.3 4.0 1.8e-13 49.8 0.0 3.7 5 0 0 5 5 5 1 WD domain, G-beta repeat p450 PF00067.17 KEY74549.1 - 5.9e-23 81.1 0.0 8.1e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Flavin_Reduct PF01613.13 KEY74549.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Flavin reductase like domain FAD_binding_4 PF01565.18 KEY74550.1 - 3.9e-16 58.7 0.1 7.2e-16 57.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Fungal_trans PF04082.13 KEY74552.1 - 7.5e-12 44.6 1.2 3.7e-11 42.3 0.2 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY74552.1 - 0.0012 18.7 9.8 0.0012 18.7 6.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KEY74553.1 - 7e-14 52.0 0.8 1.1e-13 51.4 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY74553.1 - 4.9e-09 36.1 0.3 7.8e-09 35.4 0.2 1.3 1 0 0 1 1 1 1 KR domain Ribosomal_L12 PF00542.14 KEY74553.1 - 0.029 14.3 0.2 0.055 13.4 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain adh_short_C2 PF13561.1 KEY74553.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Methyltransf_2 PF00891.13 KEY74554.1 - 4e-26 91.6 0.0 5.8e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KEY74554.1 - 9.5e-07 29.3 0.0 2.9e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KEY74554.1 - 0.00061 19.2 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KEY74554.1 - 0.0016 18.8 0.0 0.0035 17.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY74554.1 - 0.0027 18.0 0.0 0.0069 16.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY74554.1 - 0.0055 16.7 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY74554.1 - 0.006 16.3 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KEY74554.1 - 0.02 13.9 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.1 KEY74554.1 - 0.022 14.3 0.0 0.054 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 KEY74554.1 - 0.11 11.5 0.0 0.27 10.3 0.0 1.6 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G ketoacyl-synt PF00109.21 KEY74555.1 - 1.1e-65 221.5 0.0 2.3e-65 220.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 KEY74555.1 - 1.2e-63 215.0 0.0 2e-63 214.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KEY74555.1 - 5e-54 183.7 0.0 9.6e-54 182.8 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KEY74555.1 - 4.5e-53 179.5 1.9 1.5e-52 177.9 1.3 2.0 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KEY74555.1 - 2.1e-41 141.6 1.4 2.1e-41 141.6 1.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KEY74555.1 - 7e-37 125.8 0.3 1.7e-36 124.6 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KEY74555.1 - 5.4e-18 65.3 0.0 3.5e-17 62.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY74555.1 - 4.1e-09 36.9 0.0 2.9e-07 31.0 0.0 3.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY74555.1 - 6.5e-09 35.5 0.0 1.5e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY74555.1 - 6.6e-09 36.1 0.0 1e-07 32.3 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY74555.1 - 3.3e-08 33.4 0.0 1.5e-07 31.2 0.0 2.1 3 0 0 3 3 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KEY74555.1 - 4e-08 32.8 1.6 1.4e-07 31.1 0.5 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.1 KEY74555.1 - 3e-06 27.5 0.0 1.8e-05 25.0 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY74555.1 - 3.5e-05 23.0 0.0 7.8e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family 3Beta_HSD PF01073.14 KEY74555.1 - 3.8e-05 22.5 0.1 6.5e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_N PF08240.7 KEY74555.1 - 5.3e-05 22.9 0.0 0.00013 21.6 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KEY74555.1 - 9.3e-05 22.6 0.6 0.0003 21.0 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.1 KEY74555.1 - 0.00027 21.8 0.5 0.002 18.9 0.1 2.9 3 0 0 3 3 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 KEY74555.1 - 0.023 13.7 0.7 0.042 12.8 0.5 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain EB1 PF03271.12 KEY74555.1 - 0.065 13.2 0.3 0.17 11.9 0.2 1.7 1 0 0 1 1 1 0 EB1-like C-terminal motif NodS PF05401.6 KEY74555.1 - 0.094 12.0 0.0 0.47 9.8 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein S (NodS) DNA_gyraseB_C PF00986.16 KEY74555.1 - 0.25 11.0 0.0 0.6 9.9 0.0 1.5 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus Fungal_trans PF04082.13 KEY74556.1 - 4.2e-06 25.8 0.0 5.4e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1275 PF06912.6 KEY74557.1 - 3.3e-41 140.8 10.8 3.9e-41 140.5 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DIOX_N PF14226.1 KEY74558.1 - 3.7e-18 66.1 0.0 5.7e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KEY74558.1 - 4e-16 59.1 0.0 6.5e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 KEY74559.1 - 1.6e-33 115.8 35.4 1.5e-31 109.3 25.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KEY74559.1 - 0.0017 18.3 0.1 0.0017 18.3 0.1 3.8 3 1 0 3 3 3 1 Protein of unknown function (DUF1228) CcoS PF03597.10 KEY74559.1 - 0.53 9.7 0.1 0.53 9.7 0.0 3.4 3 0 0 3 3 3 0 Cytochrome oxidase maturation protein cbb3-type Abhydrolase_3 PF07859.8 KEY74560.1 - 6e-10 39.0 0.0 7.4e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KEY74560.1 - 1.2e-09 37.4 0.4 8.3e-09 34.6 0.3 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KEY74560.1 - 4.1e-06 26.5 0.0 6.3e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEY74560.1 - 1.2e-05 25.3 0.1 3.2e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KEY74560.1 - 0.0015 17.4 0.0 0.0019 17.1 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF2424 PF10340.4 KEY74560.1 - 0.0036 16.0 0.0 0.0047 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Glyco_hydro_19 PF00182.14 KEY74560.1 - 0.048 13.3 0.3 0.075 12.6 0.2 1.3 1 1 0 1 1 1 0 Chitinase class I DUF592 PF04574.8 KEY74560.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF592) FMN_dh PF01070.13 KEY74561.1 - 2.6e-97 325.8 0.0 3.7e-97 325.3 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KEY74561.1 - 1.4e-18 66.4 0.0 3.5e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 KEY74561.1 - 0.00014 20.8 1.3 0.00028 19.8 0.6 1.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KEY74561.1 - 0.00019 20.4 0.2 0.00029 19.8 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 KEY74561.1 - 0.0013 17.9 0.1 0.0024 17.0 0.1 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase Coronavirus_5 PF05528.6 KEY74561.1 - 0.045 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Coronavirus gene 5 protein Glyoxalase PF00903.20 KEY74562.1 - 2.1e-10 40.6 0.0 2.8e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KEY74562.1 - 1.2e-08 35.5 0.0 2.4e-08 34.5 0.0 1.5 2 0 0 2 2 2 1 Glyoxalase-like domain FAD_binding_3 PF01494.14 KEY74563.1 - 1.8e-65 221.3 0.0 2.3e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KEY74563.1 - 0.00075 19.4 0.3 0.0026 17.7 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KEY74563.1 - 0.0012 18.7 0.0 0.0061 16.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY74563.1 - 0.0012 19.1 0.0 0.0023 18.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEY74563.1 - 0.0022 17.1 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KEY74563.1 - 0.0028 16.6 0.6 0.0063 15.4 0.4 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Response_reg PF00072.19 KEY74564.1 - 3.1e-17 62.6 0.1 5.5e-17 61.7 0.1 1.4 1 1 0 1 1 1 1 Response regulator receiver domain SGL PF08450.7 KEY74565.1 - 0.00072 19.0 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region PQQ_3 PF13570.1 KEY74565.1 - 0.044 14.0 4.9 2.6 8.4 0.0 4.8 5 0 0 5 5 5 0 PQQ-like domain Abhydrolase_4 PF08386.5 KEY74567.1 - 1.8e-18 66.3 0.0 4.5e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KEY74567.1 - 4.4e-15 55.8 0.0 6.9e-13 48.6 0.0 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEY74567.1 - 4e-07 30.1 0.0 3e-06 27.2 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY74567.1 - 0.0072 16.0 0.0 0.2 11.4 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Fungal_trans_2 PF11951.3 KEY74568.1 - 4.5e-07 28.8 0.5 6e-07 28.4 0.3 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY74568.1 - 6.2e-07 29.2 8.5 1.3e-06 28.1 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_F17 PF04767.7 KEY74568.1 - 1.6 9.0 5.8 3.1 8.1 4.0 1.5 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein p450 PF00067.17 KEY74569.1 - 2.6e-15 55.9 0.0 4.7e-08 31.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 FSH1 PF03959.8 KEY74570.1 - 1.2e-31 109.8 0.0 1.6e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KEY74570.1 - 6.7e-05 22.8 0.5 0.00068 19.5 0.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY74570.1 - 0.00046 19.9 0.0 0.00078 19.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2119 PF09892.4 KEY74570.1 - 0.0032 16.7 0.0 0.0052 16.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2119) Abhydrolase_2 PF02230.11 KEY74570.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase MFS_1 PF07690.11 KEY74571.1 - 5.7e-43 146.9 46.2 5.7e-43 146.9 32.0 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KEY74572.1 - 3.6e-17 62.1 0.1 1.1e-16 60.5 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY74572.1 - 2.5e-10 40.1 12.9 5e-10 39.1 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 KEY74573.1 - 5.7e-38 130.9 0.6 9e-38 130.2 0.4 1.3 1 0 0 1 1 1 1 Amidase Pro_racemase PF05544.6 KEY74574.1 - 6.6e-56 189.4 0.0 1e-55 188.8 0.0 1.3 1 0 0 1 1 1 1 Proline racemase COesterase PF00135.23 KEY74575.1 - 2.9e-95 320.0 0.0 3.8e-95 319.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEY74575.1 - 2.1e-06 27.4 0.0 8.5e-06 25.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEY74575.1 - 0.076 12.2 0.1 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family HET PF06985.6 KEY74576.1 - 3.1e-08 33.8 0.0 5.5e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA_26 PF13500.1 KEY74577.1 - 1.9e-36 125.5 0.0 3.4e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Aminotran_3 PF00202.16 KEY74577.1 - 9.2e-34 116.7 0.0 1.7e-31 109.3 0.0 2.4 1 1 0 1 1 1 1 Aminotransferase class-III Sugar_tr PF00083.19 KEY74578.1 - 5.6e-71 239.4 25.2 6.7e-71 239.1 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY74578.1 - 7.7e-26 90.6 31.3 2.5e-22 79.0 15.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEY74578.1 - 3.7e-05 22.3 4.0 3.7e-05 22.3 2.8 2.6 2 1 0 2 2 2 1 MFS/sugar transport protein Ank_2 PF12796.2 KEY74580.1 - 3.1e-76 251.7 3.1 3.3e-16 59.3 0.0 9.2 6 2 1 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KEY74580.1 - 1.9e-57 188.3 27.1 4e-06 26.3 0.1 16.9 17 0 0 17 17 17 12 Ankyrin repeat Ank_3 PF13606.1 KEY74580.1 - 2.4e-44 144.9 18.6 4.3e-06 26.4 0.0 18.3 19 1 1 20 20 20 9 Ankyrin repeat Ank_4 PF13637.1 KEY74580.1 - 1.2e-37 127.5 6.4 1e-07 32.2 0.1 12.7 8 2 4 12 12 12 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY74580.1 - 3.4e-29 100.1 9.2 0.00063 19.9 0.0 12.6 9 3 4 13 13 13 6 Ankyrin repeats (many copies) Clr5 PF14420.1 KEY74580.1 - 3.4e-13 49.2 1.4 3.4e-13 49.2 1.0 1.9 2 0 0 2 2 2 1 Clr5 domain DivIC PF04977.10 KEY74581.1 - 0.042 13.3 0.4 0.071 12.6 0.1 1.5 1 1 0 1 1 1 0 Septum formation initiator Val_tRNA-synt_C PF10458.4 KEY74581.1 - 1.1 9.3 5.1 1.3 9.1 3.5 1.1 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm DUF500 PF04366.7 KEY74582.1 - 1.4e-40 137.6 0.0 2.3e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) Fringe PF02434.11 KEY74583.1 - 3e-07 29.9 0.0 6.3e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.7 KEY74583.1 - 0.0018 17.5 0.0 0.0038 16.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF604 BRO1 PF03097.13 KEY74584.1 - 2.1e-113 378.9 0.0 3.3e-113 378.2 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KEY74584.1 - 1.4e-76 257.2 3.7 1.6e-76 257.1 1.4 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV K-box PF01486.12 KEY74584.1 - 0.084 12.6 3.5 0.18 11.5 0.0 3.0 3 0 0 3 3 3 0 K-box region Band_7 PF01145.20 KEY74585.1 - 1.5e-11 44.4 0.1 1.5e-11 44.4 0.0 3.5 3 1 0 3 3 3 1 SPFH domain / Band 7 family His_Phos_2 PF00328.17 KEY74586.1 - 7e-11 42.0 0.0 6.3e-09 35.6 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Phage_Coat_B PF05356.6 KEY74586.1 - 0.034 13.8 0.7 0.082 12.6 0.1 1.9 2 0 0 2 2 2 0 Phage Coat protein B PDGLE PF13190.1 KEY74586.1 - 0.064 12.9 1.8 0.22 11.2 1.3 2.1 1 1 0 1 1 1 0 PDGLE domain 2-Hacid_dh_C PF02826.14 KEY74587.1 - 7.6e-43 145.7 0.0 1.4e-42 144.8 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KEY74587.1 - 2.3e-06 27.0 0.0 5.9e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_10 PF13460.1 KEY74587.1 - 0.088 12.7 0.2 0.58 10.1 0.0 2.1 2 0 0 2 2 2 0 NADH(P)-binding XdhC_C PF13478.1 KEY74587.1 - 0.1 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain AAA PF00004.24 KEY74588.1 - 2.6e-17 63.2 0.0 5.1e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEY74588.1 - 6.7e-05 23.0 0.1 0.0036 17.4 0.1 2.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEY74588.1 - 0.0037 17.2 0.0 0.018 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KEY74588.1 - 0.014 16.1 0.0 0.24 12.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain Zot PF05707.7 KEY74588.1 - 0.014 14.8 0.0 0.19 11.1 0.0 2.3 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_33 PF13671.1 KEY74588.1 - 0.028 14.2 0.2 0.091 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF3258 PF11646.3 KEY74588.1 - 0.049 13.8 0.3 0.16 12.1 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF3258 AAA_19 PF13245.1 KEY74588.1 - 0.12 12.1 0.2 0.27 10.9 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain ArgK PF03308.11 KEY74588.1 - 0.22 10.2 0.1 0.51 9.0 0.1 1.5 1 0 0 1 1 1 0 ArgK protein HSP20 PF00011.16 KEY74589.1 - 3.9e-17 61.9 0.1 2.1e-11 43.5 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family Troponin PF00992.15 KEY74589.1 - 0.0045 17.0 2.6 0.0073 16.3 1.8 1.2 1 0 0 1 1 1 1 Troponin Cutinase PF01083.17 KEY74590.1 - 3e-50 170.4 0.0 3.5e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 KEY74590.1 - 0.00055 19.7 0.0 0.0008 19.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.6 KEY74590.1 - 0.0012 18.3 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.11 KEY74590.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF3854 PF12965.2 KEY74591.1 - 0.03 13.9 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) Stanniocalcin PF03298.8 KEY74591.1 - 0.077 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Stanniocalcin family NMO PF03060.10 KEY74592.1 - 2.1e-41 142.1 7.7 4.9e-33 114.6 1.7 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 KEY74592.1 - 2.3e-11 43.2 0.2 3.7e-09 35.9 0.1 2.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KEY74592.1 - 3e-08 32.9 2.5 5.1e-08 32.1 1.4 1.5 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KEY74592.1 - 0.0017 17.3 0.2 0.0029 16.5 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase CorA PF01544.13 KEY74593.1 - 4.5e-13 48.8 0.0 7.6e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Takusan PF04822.8 KEY74593.1 - 0.1 12.3 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 Takusan ADH_N PF08240.7 KEY74594.1 - 6.9e-06 25.7 0.1 3.1e-05 23.6 0.1 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 KEY74596.1 - 3.1e-53 180.9 0.0 3.9e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mre11_DNA_bind PF04152.9 KEY74597.1 - 3.8e-55 186.4 0.9 6.1e-55 185.7 0.1 1.7 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 KEY74597.1 - 4.6e-24 84.9 1.0 7e-24 84.3 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEY74597.1 - 8.9e-07 28.8 0.0 2.8e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mcm10 PF09332.6 KEY74597.1 - 0.026 13.8 5.6 0.051 12.9 3.9 1.5 1 0 0 1 1 1 0 Mcm10 replication factor Pox_Ag35 PF03286.9 KEY74597.1 - 1 8.8 8.6 2.4 7.6 6.0 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein MFS_1 PF07690.11 KEY74598.1 - 5.3e-19 68.1 26.4 1.1e-16 60.5 12.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 KEY74598.1 - 7.9e-07 28.5 4.9 7.9e-07 28.5 3.4 2.4 2 1 0 2 2 2 1 Nodulin-like Claudin_3 PF06653.6 KEY74598.1 - 0.051 13.2 0.4 0.051 13.2 0.3 2.7 4 1 0 4 4 4 0 Tight junction protein, Claudin-like Epimerase PF01370.16 KEY74600.1 - 1.1e-21 77.3 0.0 2e-21 76.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KEY74600.1 - 9.9e-11 41.0 0.1 7.7e-08 31.5 0.0 2.9 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KEY74600.1 - 6.6e-10 38.3 0.0 9.9e-10 37.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KEY74600.1 - 2.4e-09 36.4 0.0 4.4e-08 32.3 0.0 2.5 2 1 1 3 3 3 1 Male sterility protein 3Beta_HSD PF01073.14 KEY74600.1 - 0.0016 17.2 0.0 0.0097 14.6 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KEY74600.1 - 0.0096 15.6 1.2 0.2 11.2 0.0 2.7 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 KEY74600.1 - 0.047 13.6 2.0 2.2 8.1 0.0 2.8 3 0 0 3 3 3 0 short chain dehydrogenase Inositol_P PF00459.20 KEY74601.1 - 1.9e-34 119.2 0.0 2.8e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family Rep-A_N PF04057.7 KEY74602.1 - 0.04 13.7 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain TALPID3 PF15324.1 KEY74602.1 - 2.4 5.3 14.9 3.6 4.7 10.3 1.1 1 0 0 1 1 1 0 Hedgehog signalling target GMC_oxred_N PF00732.14 KEY74603.1 - 2.1e-64 217.5 0.0 2.9e-64 217.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY74603.1 - 7.1e-32 110.6 0.0 1.2e-31 109.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lipocalin_2 PF08212.7 KEY74603.1 - 3.6e-19 68.9 0.0 6.6e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Lipocalin-like domain Lycopene_cycl PF05834.7 KEY74603.1 - 0.18 10.6 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GST_N PF02798.15 KEY74604.1 - 1.7e-13 50.5 0.0 3.6e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEY74604.1 - 5.4e-09 35.9 0.0 8.7e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KEY74604.1 - 3.9e-07 30.2 0.0 7.9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain FAD_binding_4 PF01565.18 KEY74606.1 - 3.8e-21 75.0 4.5 2.2e-20 72.5 3.2 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KEY74606.1 - 2.8e-08 33.5 0.1 5.7e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like F-box PF00646.28 KEY74607.1 - 0.00064 19.3 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KEY74607.1 - 0.013 15.1 0.1 0.034 13.8 0.0 1.7 1 0 0 1 1 1 0 F-box-like N6_N4_Mtase PF01555.13 KEY74607.1 - 0.078 12.4 0.9 0.17 11.3 0.6 1.5 1 0 0 1 1 1 0 DNA methylase SnoaL PF07366.7 KEY74608.1 - 3.8e-24 84.6 0.0 4.6e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KEY74608.1 - 2.2e-12 47.2 0.0 3.2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DDE_Tnp_1_7 PF13843.1 KEY74609.1 - 2.6e-41 141.8 0.0 1.6e-40 139.2 0.0 1.9 1 1 0 1 1 1 1 Transposase IS4 Zn_clus PF00172.13 KEY74611.1 - 0.38 10.6 14.3 0.71 9.8 9.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KEY74612.1 - 1e-06 28.7 0.1 1.9e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase CBM-like PF14683.1 KEY74613.1 - 8.9e-31 106.7 0.0 1.5e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 KEY74613.1 - 3.2e-22 78.4 0.1 1.1e-21 76.6 0.1 2.0 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 KEY74613.1 - 2.2e-08 34.0 0.5 5.1e-07 29.6 0.1 2.4 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 KEY74613.1 - 0.04 13.7 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) EF-hand_6 PF13405.1 KEY74613.1 - 0.042 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.27 KEY74613.1 - 0.077 12.3 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 EF hand DUF1610 PF07754.6 KEY74613.1 - 0.17 12.0 1.6 0.82 9.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Semialdhyde_dh PF01118.19 KEY74614.1 - 6.7e-22 78.0 0.1 1.5e-21 76.9 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KEY74614.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus FAD_binding_4 PF01565.18 KEY74616.1 - 4.8e-19 68.2 0.8 7.6e-19 67.5 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY74616.1 - 3.1e-10 39.7 0.3 6.3e-10 38.8 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like Methyltransf_26 PF13659.1 KEY74616.1 - 0.085 12.8 0.0 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain F-box PF00646.28 KEY74617.1 - 0.00013 21.5 1.0 0.00056 19.4 0.7 2.1 1 0 0 1 1 1 1 F-box domain IL34 PF15036.1 KEY74617.1 - 0.0026 17.3 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 Interleukin 34 F-box-like PF12937.2 KEY74617.1 - 0.064 12.9 0.7 0.064 12.9 0.5 1.8 2 0 0 2 2 2 0 F-box-like HATPase_c PF02518.21 KEY74618.1 - 9.6e-23 80.0 0.0 2e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KEY74618.1 - 1.4e-19 70.1 0.0 3.2e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KEY74618.1 - 1.6e-12 47.2 0.0 5.4e-12 45.5 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 KEY74618.1 - 2.1e-08 34.4 0.5 7.8e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.1 KEY74618.1 - 9.8e-05 22.4 0.0 0.024 14.7 0.0 2.8 2 0 0 2 2 2 2 GAF domain ABC2_membrane PF01061.19 KEY74619.1 - 1.1e-81 272.9 64.1 1.4e-41 142.0 12.3 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KEY74619.1 - 3.7e-37 127.6 0.0 1.8e-19 70.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KEY74619.1 - 8.3e-31 105.7 2.1 6.8e-25 86.7 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KEY74619.1 - 6.5e-16 58.2 0.0 1.9e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KEY74619.1 - 5.1e-08 32.5 0.1 0.0055 16.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain ABC2_membrane_3 PF12698.2 KEY74619.1 - 3e-06 26.5 15.1 3e-06 26.5 10.4 3.1 2 2 0 2 2 2 1 ABC-2 family transporter protein DUF258 PF03193.11 KEY74619.1 - 9.8e-06 24.8 0.0 0.0011 18.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KEY74619.1 - 7.3e-05 22.6 1.5 0.0026 17.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 KEY74619.1 - 0.0003 20.2 2.1 0.0028 17.0 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 KEY74619.1 - 0.00073 19.0 1.3 0.041 13.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 KEY74619.1 - 0.0019 17.4 0.0 0.0069 15.6 0.0 1.9 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KEY74619.1 - 0.0035 17.4 0.7 0.29 11.2 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEY74619.1 - 0.0054 17.0 0.2 0.045 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KEY74619.1 - 0.0087 15.7 1.2 3 7.4 0.1 2.7 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.18 KEY74619.1 - 0.012 15.5 0.1 8.2 6.4 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.1 KEY74619.1 - 0.013 15.4 7.5 0.014 15.4 0.1 3.2 3 0 0 3 3 3 0 AAA ATPase domain AAA_17 PF13207.1 KEY74619.1 - 0.015 16.1 0.0 0.096 13.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEY74619.1 - 0.018 15.2 0.0 8.2 6.6 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_21 PF13304.1 KEY74619.1 - 0.09 12.7 0.0 0.75 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KEY74619.1 - 0.22 12.0 0.0 30 5.1 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein CN_hydrolase PF00795.17 KEY74620.1 - 3.5e-21 75.4 0.0 5.6e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase WLM PF08325.5 KEY74621.1 - 6.2e-47 159.8 0.1 9.3e-46 156.0 0.0 2.0 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.12 KEY74621.1 - 0.00053 19.8 0.9 0.0011 18.7 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 KEY74621.1 - 0.00094 18.8 0.3 0.0018 17.9 0.2 1.4 1 0 0 1 1 1 1 SprT-like family ubiquitin PF00240.18 KEY74621.1 - 0.017 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Reprolysin_5 PF13688.1 KEY74621.1 - 0.039 13.8 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Ubiquitin_2 PF14560.1 KEY74621.1 - 0.089 13.0 0.0 0.23 11.7 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-like domain ER_lumen_recept PF00810.13 KEY74622.1 - 2.9e-54 183.5 4.3 4.5e-54 182.9 3.0 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor TFIID_30kDa PF03540.8 KEY74623.1 - 2.6e-26 91.1 0.5 4e-26 90.6 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.1 KEY74623.1 - 0.03 14.7 0.3 0.048 14.1 0.2 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Ribosomal_S19 PF00203.16 KEY74624.1 - 2.9e-24 84.4 0.0 4e-24 84.0 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S19 HET PF06985.6 KEY74625.1 - 1.6e-29 102.8 0.1 2.8e-29 102.0 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_C48 PF02902.14 KEY74626.1 - 0.0021 17.7 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain FMN_dh PF01070.13 KEY74627.1 - 3e-122 407.9 0.5 3e-122 407.9 0.4 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Sulfatase PF00884.18 KEY74627.1 - 1.5e-56 191.8 0.1 2.1e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Sulfatase IMPDH PF00478.20 KEY74627.1 - 1.4e-07 30.7 2.6 4.6e-07 29.0 1.8 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KEY74627.1 - 3.9e-07 29.3 1.7 3.7e-06 26.1 1.0 2.2 1 1 1 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.10 KEY74627.1 - 7.1e-07 28.6 0.7 1.2e-06 27.9 0.5 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.16 KEY74627.1 - 1.9e-05 23.8 0.6 0.00041 19.4 0.0 2.1 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.9 KEY74627.1 - 3e-05 23.2 9.5 0.0027 16.8 0.1 4.0 3 1 1 4 4 4 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KEY74627.1 - 0.00044 19.5 0.4 0.0066 15.7 0.0 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein PcrB PF01884.12 KEY74627.1 - 0.00068 18.9 2.0 0.14 11.4 0.2 2.3 1 1 1 2 2 2 2 PcrB family Phosphodiest PF01663.17 KEY74627.1 - 0.0014 18.0 0.1 0.73 9.0 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Dus PF01207.12 KEY74627.1 - 0.013 14.3 0.0 0.49 9.1 0.0 2.4 2 1 0 2 2 2 0 Dihydrouridine synthase (Dus) IGPS PF00218.16 KEY74627.1 - 0.11 11.5 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase G3P_antiterm PF04309.7 KEY74627.1 - 0.26 10.3 0.9 13 4.7 0.0 2.3 1 1 1 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Peptidase_MA_2 PF13485.1 KEY74628.1 - 7.1e-07 29.3 1.2 1.2e-06 28.5 0.8 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2268 PF10026.4 KEY74628.1 - 0.00028 20.3 0.1 0.00045 19.6 0.1 1.3 1 0 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) Peptidase_M61 PF05299.7 KEY74628.1 - 0.00048 20.0 1.9 0.023 14.6 1.3 2.5 1 1 0 1 1 1 1 M61 glycyl aminopeptidase Peptidase_M1 PF01433.15 KEY74628.1 - 0.034 13.2 0.1 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M1 E1-E2_ATPase PF00122.15 KEY74632.1 - 1.5e-26 92.8 0.2 1.7e-26 92.7 0.1 1.0 1 0 0 1 1 1 1 E1-E2 ATPase EKR PF10371.4 KEY74632.1 - 0.013 15.0 0.2 0.47 10.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function MFS_1 PF07690.11 KEY74633.1 - 4.3e-09 35.5 1.8 5.6e-09 35.1 1.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Neurensin PF14927.1 KEY74633.1 - 0.069 12.5 0.6 0.86 8.9 0.0 2.2 2 0 0 2 2 2 0 Neurensin 4HBT PF03061.17 KEY74634.1 - 3.8e-06 26.9 0.1 7.3e-06 26.0 0.1 1.5 1 1 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 KEY74634.1 - 0.0033 17.3 0.0 2.9 7.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4442) Beta-lactamase PF00144.19 KEY74635.1 - 5.7e-41 140.6 0.2 6.9e-41 140.3 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Cellulase PF00150.13 KEY74636.1 - 5.8e-52 176.6 1.4 7e-52 176.3 1.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1977 PF09320.6 KEY74637.1 - 1.2e-23 83.3 0.0 2.3e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 KEY74637.1 - 2.3e-21 75.2 0.1 4.4e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DUF544 PF04424.8 KEY74638.1 - 1e-14 54.4 0.0 1.5e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) 4HBT PF03061.17 KEY74638.1 - 0.004 17.2 0.5 0.04 14.0 0.0 2.4 2 0 0 2 2 2 1 Thioesterase superfamily Pec_lyase_C PF00544.14 KEY74639.1 - 5.7e-43 146.7 0.9 1e-42 145.9 0.6 1.4 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KEY74639.1 - 0.00016 21.5 7.8 0.08 12.6 2.3 2.4 1 1 1 2 2 2 2 Right handed beta helix region Steroid_dh PF02544.11 KEY74640.1 - 4.4e-24 84.9 0.6 2.4e-23 82.5 0.4 2.0 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KEY74640.1 - 0.0015 17.8 1.6 0.0032 16.8 1.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Epimerase PF01370.16 KEY74641.1 - 1.7e-15 57.1 0.1 2.8e-15 56.4 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY74641.1 - 2.3e-11 44.0 0.0 6.1e-11 42.6 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEY74641.1 - 8.3e-09 34.5 0.0 1.3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KEY74641.1 - 5.7e-05 22.4 0.0 8.9e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KEY74641.1 - 0.00011 22.1 0.1 0.00069 19.5 0.0 2.2 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KEY74641.1 - 0.00087 18.2 0.1 0.011 14.6 0.0 2.2 3 0 0 3 3 3 1 Male sterility protein Saccharop_dh PF03435.13 KEY74641.1 - 0.0027 16.7 0.0 0.0041 16.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 KEY74641.1 - 0.008 15.1 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein AlaDh_PNT_C PF01262.16 KEY74641.1 - 0.095 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ABC2_membrane PF01061.19 KEY74642.1 - 4.8e-60 202.3 46.0 4.9e-32 110.8 11.4 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 KEY74642.1 - 7.2e-42 142.9 0.0 1.2e-20 74.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KEY74642.1 - 4e-25 87.4 2.8 9.1e-20 70.2 0.0 2.6 2 0 0 2 2 2 2 CDR ABC transporter AAA_25 PF13481.1 KEY74642.1 - 2.3e-07 30.4 0.2 0.00012 21.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 KEY74642.1 - 2.5e-07 30.9 0.0 0.0082 16.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.1 KEY74642.1 - 2.9e-07 30.7 0.0 0.013 15.4 0.0 3.6 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KEY74642.1 - 2.9e-07 30.6 0.8 0.00057 19.9 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 KEY74642.1 - 1.9e-05 25.4 0.0 0.019 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KEY74642.1 - 2.6e-05 24.1 0.1 0.14 11.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 KEY74642.1 - 2.7e-05 23.4 0.2 0.00013 21.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 KEY74642.1 - 0.00011 22.5 0.0 0.23 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KEY74642.1 - 0.00011 21.5 3.3 0.0047 16.4 0.2 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KEY74642.1 - 0.00021 20.8 0.7 0.21 11.0 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family UPF0079 PF02367.12 KEY74642.1 - 0.00033 20.2 1.2 0.16 11.5 0.3 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KEY74642.1 - 0.00041 20.0 0.2 0.73 9.4 0.2 2.5 2 0 0 2 2 2 2 NACHT domain AAA_19 PF13245.1 KEY74642.1 - 0.0006 19.5 0.0 0.84 9.4 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 KEY74642.1 - 0.00062 19.7 0.4 0.029 14.3 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KEY74642.1 - 0.0014 18.2 0.3 1.1 8.8 0.2 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KEY74642.1 - 0.0014 19.0 0.1 2 8.9 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein ABC_trans_N PF14510.1 KEY74642.1 - 0.0016 18.4 0.0 0.0041 17.1 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal T2SE PF00437.15 KEY74642.1 - 0.0023 16.8 0.2 1.3 7.8 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein cobW PF02492.14 KEY74642.1 - 0.0043 16.5 0.9 0.24 10.8 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Tub PF01167.13 KEY74642.1 - 0.0056 15.6 0.0 0.0098 14.8 0.0 1.3 1 0 0 1 1 1 1 Tub family AAA PF00004.24 KEY74642.1 - 0.0062 16.7 0.0 3.1 8.0 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KEY74642.1 - 0.0082 15.2 0.0 0.056 12.5 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin PduV-EutP PF10662.4 KEY74642.1 - 0.01 15.3 0.6 0.8 9.1 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 KEY74642.1 - 0.016 15.1 0.1 0.62 10.0 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.10 KEY74642.1 - 0.02 14.5 0.2 9.6 5.8 0.0 3.1 3 0 0 3 3 3 0 NTPase Pox_A32 PF04665.7 KEY74642.1 - 0.031 13.5 0.1 5.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_10 PF12846.2 KEY74642.1 - 0.044 13.2 0.7 3.6 6.9 0.2 2.4 2 0 0 2 2 2 0 AAA-like domain ABC_ATPase PF09818.4 KEY74642.1 - 0.046 12.3 0.5 0.14 10.7 0.1 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_23 PF13476.1 KEY74642.1 - 0.052 13.8 0.9 0.074 13.3 0.1 1.5 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.17 KEY74642.1 - 0.061 12.1 0.9 0.53 9.1 0.1 2.1 2 0 0 2 2 2 0 NB-ARC domain SMC_N PF02463.14 KEY74642.1 - 0.081 12.1 0.0 20 4.2 0.0 2.9 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain Septin PF00735.13 KEY74642.1 - 0.081 11.9 0.1 11 4.8 0.0 2.2 2 0 0 2 2 2 0 Septin MobB PF03205.9 KEY74642.1 - 0.12 12.1 0.1 17 5.1 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 KEY74642.1 - 0.12 12.3 0.1 2.6 8.0 0.0 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 KEY74642.1 - 0.16 12.1 0.0 11 6.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 KEY74642.1 - 0.19 11.3 0.5 19 4.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KEY74642.1 - 0.22 11.4 0.0 11 5.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain FeoB_N PF02421.13 KEY74642.1 - 0.25 10.6 0.4 5.8 6.1 0.1 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B Arch_ATPase PF01637.13 KEY74642.1 - 0.28 10.8 0.0 5.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_15 PF13175.1 KEY74642.1 - 0.55 9.2 0.0 1.6 7.6 0.0 1.7 3 0 0 3 3 1 0 AAA ATPase domain SRP54 PF00448.17 KEY74642.1 - 0.68 9.3 1.8 11 5.4 0.4 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.12 KEY74642.1 - 0.7 9.3 2.7 10 5.5 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Fungal_trans PF04082.13 KEY74643.1 - 8.8e-17 60.8 1.1 1.2e-16 60.3 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY74643.1 - 1.3e-05 24.9 11.1 1.3e-05 24.9 7.7 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GED PF02212.13 KEY74644.1 - 0.052 13.4 1.2 0.3 10.9 0.8 2.3 1 1 0 1 1 1 0 Dynamin GTPase effector domain DUF4358 PF14270.1 KEY74644.1 - 0.16 11.8 0.6 1.4 8.7 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4358) Pirin PF02678.11 KEY74645.1 - 2.4e-31 107.7 0.3 2.1e-30 104.7 0.2 2.1 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 KEY74645.1 - 2.7e-21 75.6 0.0 4.1e-20 71.7 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 KEY74645.1 - 2e-07 30.3 1.2 7.7e-05 22.1 0.3 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KEY74645.1 - 0.00034 19.9 0.4 0.94 8.9 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF861) Peptidase_M19 PF01244.16 KEY74646.1 - 2.3e-101 338.9 0.1 2.7e-101 338.7 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) CN_hydrolase PF00795.17 KEY74647.1 - 8.2e-19 67.6 0.0 4.5e-18 65.2 0.0 1.9 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase 2-Hacid_dh_C PF02826.14 KEY74648.1 - 1.3e-39 135.2 0.0 2.7e-39 134.1 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 KEY74648.1 - 1.6e-20 73.3 0.1 7.5e-15 54.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase 2-Hacid_dh PF00389.25 KEY74648.1 - 6.2e-16 58.0 0.0 1e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KEY74648.1 - 0.004 17.0 0.0 0.013 15.3 0.0 1.9 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_2 PF00890.19 KEY74648.1 - 0.024 13.4 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain F420_oxidored PF03807.12 KEY74648.1 - 0.13 12.7 0.0 0.56 10.6 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KEY74648.1 - 0.23 11.4 0.4 19 5.2 0.0 3.0 3 0 0 3 3 3 0 TrkA-N domain Fungal_trans PF04082.13 KEY74649.1 - 1e-30 106.4 0.0 1.8e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_1_2 PF00155.16 KEY74650.1 - 2.4e-62 211.0 0.0 2.8e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_M20 PF01546.23 KEY74651.1 - 7e-27 94.1 0.1 9.7e-27 93.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KEY74651.1 - 4e-15 55.5 0.0 6.1e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KEY74651.1 - 0.00075 19.2 0.1 0.00099 18.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 MFS_1 PF07690.11 KEY74652.1 - 2.3e-41 141.6 43.3 9.1e-37 126.5 19.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 KEY74652.1 - 0.0038 16.7 1.2 0.0038 16.7 0.8 2.1 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 DUF1772 PF08592.6 KEY74652.1 - 3 7.5 14.2 0.42 10.3 0.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) Hydantoinase_B PF02538.9 KEY74653.1 - 4.2e-181 602.7 0.0 5.3e-181 602.4 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KEY74653.1 - 1.4e-83 280.3 0.0 2.9e-83 279.3 0.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KEY74653.1 - 1.6e-55 187.3 0.4 4.7e-54 182.5 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Pox_A12 PF04651.8 KEY74654.1 - 0.2 11.7 2.8 0.22 11.6 0.2 2.2 2 0 0 2 2 2 0 Poxvirus A12 protein ADIP PF11559.3 KEY74654.1 - 2.4 8.0 11.0 0.15 11.9 2.8 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.16 KEY74655.1 - 6.5e-08 32.4 2.9 1.6e-07 31.1 2.0 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KEY74655.1 - 0.00093 18.9 6.2 0.0022 17.7 4.3 1.6 1 0 0 1 1 1 1 Basic region leucine zipper TTKRSYEDQ PF10212.4 KEY74655.1 - 0.028 13.3 0.0 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein MFS_1 PF07690.11 KEY74656.1 - 5.2e-20 71.4 57.1 5.4e-19 68.1 36.7 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KEY74656.1 - 3.6e-05 22.1 26.1 5.2e-05 21.6 18.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATP1G1_PLM_MAT8 PF02038.11 KEY74656.1 - 0.92 8.5 3.5 19 4.3 0.1 3.5 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family F-box-like PF12937.2 KEY74657.1 - 0.00027 20.6 0.6 0.002 17.7 0.5 2.3 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 KEY74657.1 - 0.012 15.2 1.5 1.4 8.6 0.2 2.7 2 0 0 2 2 2 0 F-box domain Ank_2 PF12796.2 KEY74658.1 - 8e-11 42.1 0.1 1.4e-10 41.3 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KEY74658.1 - 3.9e-10 39.0 1.1 0.00081 19.0 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 KEY74658.1 - 7.6e-08 31.8 0.3 0.018 15.2 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KEY74658.1 - 3.1e-07 30.7 0.1 0.038 14.5 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY74658.1 - 3.3e-06 27.1 1.0 0.014 15.6 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Glyco_hydro_32N PF00251.15 KEY74659.1 - 2.2e-157 523.1 6.9 1.3e-70 238.2 0.2 3.1 3 0 0 3 3 3 3 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KEY74659.1 - 3.8e-31 107.3 0.6 4.3e-18 65.4 0.1 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 KEY74659.1 - 0.35 10.8 12.4 1.7 8.8 0.1 4.6 4 0 0 4 4 4 0 BNR/Asp-box repeat AAA PF00004.24 KEY74662.1 - 8.8e-19 68.0 0.0 5.9e-18 65.3 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEY74662.1 - 0.00044 20.4 0.2 0.0021 18.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEY74662.1 - 0.00056 20.7 0.0 0.00056 20.7 0.0 3.4 4 0 0 4 4 2 1 AAA domain AAA_33 PF13671.1 KEY74662.1 - 0.0026 17.6 0.0 0.035 13.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KEY74662.1 - 0.0039 16.9 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEY74662.1 - 0.004 17.1 0.0 0.014 15.3 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 KEY74662.1 - 0.0049 17.1 1.5 0.025 14.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KEY74662.1 - 0.019 14.8 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KEY74662.1 - 0.02 14.5 0.4 0.99 9.0 0.2 3.0 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 KEY74662.1 - 0.029 14.0 3.0 0.084 12.6 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain RuvB_N PF05496.7 KEY74662.1 - 0.074 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Flavi_M PF01004.14 KEY74663.1 - 0.0092 15.3 0.0 0.024 14.0 0.0 1.7 1 0 0 1 1 1 1 Flavivirus envelope glycoprotein M Bac_rhamnosid PF05592.6 KEY74665.1 - 4.1e-172 572.9 0.0 5e-172 572.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 KEY74665.1 - 5.1e-54 182.3 0.1 1.9e-53 180.5 0.0 1.9 2 0 0 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain adh_short PF00106.20 KEY74670.1 - 7.5e-31 107.2 2.2 1e-30 106.8 1.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY74670.1 - 1.9e-22 80.1 0.6 1.1e-21 77.7 0.4 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY74670.1 - 1.3e-15 57.5 0.5 1.8e-15 57.0 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY74670.1 - 0.00025 20.5 0.3 0.001 18.5 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Dabb PF07876.7 KEY74671.1 - 3.4e-21 75.4 0.0 4.1e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain RPE65 PF03055.10 KEY74672.1 - 1.9e-95 320.2 0.0 2.4e-95 319.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Cation_efflux PF01545.16 KEY74673.1 - 7.9e-29 100.6 4.2 8.9e-29 100.4 2.9 1.0 1 0 0 1 1 1 1 Cation efflux family WHH PF14414.1 KEY74673.1 - 0.05 12.8 0.2 3.5 6.9 0.1 2.4 2 0 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH DUF3425 PF11905.3 KEY74674.1 - 9.3e-30 103.2 0.6 1.7e-29 102.4 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Transp_cyt_pur PF02133.10 KEY74675.1 - 1.7e-31 109.2 32.4 1.4e-30 106.2 22.5 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin FMN_dh PF01070.13 KEY74677.1 - 2.6e-82 276.5 0.0 8.8e-50 169.5 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase ThiG PF05690.9 KEY74677.1 - 7.4e-05 21.9 0.0 0.36 9.8 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 KEY74677.1 - 0.00056 19.1 0.1 0.0011 18.2 0.0 1.5 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.16 KEY74677.1 - 0.01 15.1 0.1 2.6 7.2 0.0 2.9 1 1 2 3 3 3 0 Histidine biosynthesis protein DHO_dh PF01180.16 KEY74677.1 - 0.011 14.7 0.0 2.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase IMPDH PF00478.20 KEY74677.1 - 0.012 14.4 0.1 0.066 12.0 0.0 1.9 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KEY74677.1 - 0.047 12.5 0.0 0.3 9.9 0.0 1.9 2 0 0 2 2 2 0 Conserved region in glutamate synthase IGPS PF00218.16 KEY74677.1 - 0.11 11.5 0.0 0.69 8.9 0.0 2.0 1 1 1 2 2 2 0 Indole-3-glycerol phosphate synthase DUF572 PF04502.8 KEY74678.1 - 1.1e-59 202.3 0.6 1.3e-59 202.0 0.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) RNA_pol_N PF01194.12 KEY74678.1 - 0.16 12.0 1.7 0.35 10.9 0.0 2.4 3 0 0 3 3 3 0 RNA polymerases N / 8 kDa subunit zinc_ribbon_2 PF13240.1 KEY74678.1 - 1.1 8.8 4.6 0.71 9.4 1.1 2.3 2 1 0 2 2 2 0 zinc-ribbon domain Glyco_hydro_43 PF04616.9 KEY74679.1 - 7.1e-34 117.1 7.6 9.4e-34 116.7 5.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 APH PF01636.18 KEY74680.1 - 1.5e-11 44.5 0.3 2.3e-11 43.8 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KEY74680.1 - 0.00088 18.3 0.0 0.016 14.3 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KEY74680.1 - 0.0017 17.9 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KEY74680.1 - 0.013 14.6 0.0 0.1 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain Helicase_C_2 PF13307.1 KEY74681.1 - 2.5e-57 193.4 0.0 5.2e-57 192.4 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KEY74681.1 - 2e-45 154.3 0.0 3.2e-45 153.6 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 SNF2_N PF00176.18 KEY74681.1 - 0.083 11.6 0.0 0.32 9.7 0.0 1.8 2 0 0 2 2 2 0 SNF2 family N-terminal domain Ribosomal_L18e PF00828.14 KEY74683.1 - 4.3e-13 49.7 0.0 4.3e-13 49.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Pkinase PF00069.20 KEY74684.1 - 4.1e-42 144.1 0.0 1.4e-37 129.2 0.0 3.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEY74684.1 - 4.8e-15 55.3 0.0 3e-09 36.3 0.0 3.7 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KEY74684.1 - 2.9e-05 23.9 0.3 0.021 14.5 0.1 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KEY74684.1 - 0.0013 17.8 0.0 0.07 12.0 0.0 2.4 2 0 0 2 2 2 1 Kinase-like DUF3291 PF11695.3 KEY74684.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) Cnd1_N PF12922.2 KEY74685.1 - 3.1e-58 196.2 1.3 1.1e-57 194.4 0.0 2.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 KEY74685.1 - 1.7e-55 187.6 2.4 2.3e-52 177.4 0.2 2.9 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KEY74685.1 - 5.2e-11 42.6 6.6 9.2e-06 25.8 0.1 6.1 5 2 1 6 6 6 2 HEAT repeats HEAT PF02985.17 KEY74685.1 - 3.7e-08 32.7 8.8 0.029 14.4 0.0 6.5 8 0 0 8 8 6 2 HEAT repeat HEAT_EZ PF13513.1 KEY74685.1 - 1.3e-06 28.7 5.3 0.016 15.7 0.1 5.4 5 0 0 5 5 5 1 HEAT-like repeat Adaptin_N PF01602.15 KEY74685.1 - 2.3e-05 22.9 2.1 0.017 13.4 0.0 3.5 3 1 0 3 3 3 2 Adaptin N terminal region DUF2435 PF10363.4 KEY74685.1 - 0.0025 17.6 0.0 0.61 10.0 0.0 3.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) Ald_Xan_dh_C2 PF02738.13 KEY74685.1 - 0.0054 15.1 0.0 0.0086 14.4 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Cohesin_HEAT PF12765.2 KEY74685.1 - 0.023 14.6 0.1 13 5.9 0.1 3.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Corona_nucleoca PF00937.13 KEY74685.1 - 0.16 10.9 0.3 0.33 9.8 0.2 1.5 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Cnd3 PF12719.2 KEY74685.1 - 0.21 10.5 8.4 0.046 12.7 1.1 3.3 3 2 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain NIF PF03031.13 KEY74686.1 - 2.5e-28 98.7 0.0 8.2e-28 97.0 0.0 1.9 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 KEY74686.1 - 1.1e-08 34.7 0.3 2.9e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 KEY74686.1 - 2.7e-07 30.6 0.0 7.8e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Ribosomal_S2 PF00318.15 KEY74686.1 - 0.038 13.1 0.0 0.074 12.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S2 adh_short PF00106.20 KEY74687.1 - 3.1e-15 56.5 0.9 3.1e-15 56.5 0.7 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY74687.1 - 3.3e-09 36.6 0.3 1.6e-08 34.4 0.1 1.9 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KEY74687.1 - 0.032 14.0 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 KEY74687.1 - 0.068 12.0 0.0 0.089 11.6 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GRIM-19 PF06212.7 KEY74688.1 - 4.1e-21 75.0 0.9 2.9e-20 72.3 0.6 2.1 1 1 0 1 1 1 1 GRIM-19 protein MFS_1 PF07690.11 KEY74690.1 - 5.4e-26 91.1 50.4 3.4e-23 81.9 24.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY74690.1 - 7.7e-05 21.4 37.6 0.0031 16.1 10.9 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter DUF4246 PF14033.1 KEY74692.1 - 4.2e-11 42.1 0.2 5.6e-11 41.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) HET PF06985.6 KEY74693.1 - 2.7e-15 56.7 0.0 1.7e-14 54.1 0.0 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Opi1 PF08618.5 KEY74694.1 - 0.0086 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Opi1 DUF4407 PF14362.1 KEY74694.1 - 5.8 5.7 6.0 0.99 8.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HET PF06985.6 KEY74696.1 - 5.2e-34 117.3 0.1 1.2e-33 116.1 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribonuc_L-PSP PF01042.16 KEY74697.1 - 2.4e-40 137.0 0.0 2.6e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Abhydrolase_3 PF07859.8 KEY74698.1 - 6.5e-62 208.8 0.1 8.3e-62 208.4 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KEY74698.1 - 0.00032 19.5 0.3 0.00051 18.8 0.0 1.4 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.16 KEY74698.1 - 0.0016 17.6 0.1 0.0059 15.8 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEY74698.1 - 0.0023 17.6 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KEY74698.1 - 0.053 12.1 0.0 0.094 11.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) SGL PF08450.7 KEY74699.1 - 1.7e-59 201.1 0.0 2.1e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region DUF839 PF05787.8 KEY74699.1 - 0.004 16.1 0.2 0.065 12.1 0.0 2.3 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF839) NHL PF01436.16 KEY74699.1 - 0.024 14.6 0.0 0.48 10.4 0.0 2.6 2 0 0 2 2 2 0 NHL repeat Arylesterase PF01731.15 KEY74699.1 - 0.036 14.0 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 Arylesterase Reg_prop PF07494.6 KEY74699.1 - 0.14 12.2 0.4 7.9 6.8 0.0 3.5 3 0 0 3 3 3 0 Two component regulator propeller Fungal_trans PF04082.13 KEY74700.1 - 3.1e-46 157.3 3.5 4.4e-46 156.8 2.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KEY74700.1 - 1.7e-08 34.3 14.4 0.00011 22.3 1.5 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY74700.1 - 9.9e-06 25.5 10.5 0.016 15.4 1.5 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KEY74700.1 - 0.0011 18.7 0.3 0.0027 17.5 0.2 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEY74700.1 - 0.022 15.0 2.4 0.022 15.0 1.7 3.6 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_2 PF12756.2 KEY74700.1 - 0.058 13.5 0.4 0.15 12.2 0.3 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KEY74700.1 - 0.65 10.2 2.1 1.1 9.4 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Transp_cyt_pur PF02133.10 KEY74701.1 - 3.1e-92 309.4 37.3 3.5e-92 309.2 25.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin FAD_binding_4 PF01565.18 KEY74704.1 - 5.7e-15 55.0 0.2 9.8e-15 54.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY74704.1 - 0.00021 21.1 0.3 0.00045 20.0 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF3588 PF12140.3 KEY74705.1 - 0.097 12.7 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3588) Tox-GHH PF15636.1 KEY74705.1 - 0.12 12.0 0.3 0.29 10.8 0.2 1.6 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin RNase_H PF00075.19 KEY74707.1 - 0.0071 16.6 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 RNase H CobT PF06213.7 KEY74707.1 - 0.034 13.2 8.2 0.044 12.9 5.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.8 KEY74707.1 - 0.041 13.4 7.9 0.069 12.7 5.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.7 KEY74707.1 - 0.32 8.8 13.8 0.41 8.5 9.6 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KEY74707.1 - 0.41 9.0 12.2 0.52 8.7 8.5 1.1 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 KEY74707.1 - 0.97 8.6 6.3 1.4 8.1 4.4 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 KEY74707.1 - 2.3 6.8 21.4 3.6 6.1 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.11 KEY74707.1 - 3.8 6.4 9.2 5.3 5.9 6.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2722 PF10846.3 KEY74707.1 - 4.2 6.2 4.9 5.6 5.8 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Dicty_REP PF05086.7 KEY74707.1 - 4.2 4.9 4.8 5.3 4.6 3.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CDC45 PF02724.9 KEY74707.1 - 4.5 5.1 8.3 5.9 4.7 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 KEY74707.1 - 6.2 6.3 12.6 9 5.8 8.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein GRAM PF02893.15 KEY74708.1 - 2e-27 94.5 0.3 5.5e-15 54.6 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 KEY74708.1 - 7.1e-25 87.3 0.0 1.4e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 KEY74708.1 - 9.4e-13 48.2 0.0 3.4e-12 46.4 0.0 2.1 1 0 0 1 1 1 1 PH domain UDPGT PF00201.13 KEY74708.1 - 1.4e-07 30.4 0.0 2.2e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_8 PF15409.1 KEY74708.1 - 6.4e-05 22.9 0.1 0.00033 20.6 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 KEY74708.1 - 0.00028 21.1 0.2 0.00078 19.6 0.2 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 KEY74708.1 - 0.004 17.0 0.0 0.009 15.8 0.0 1.5 1 0 0 1 1 1 1 PH domain WD40 PF00400.27 KEY74709.1 - 8.3e-15 54.0 6.8 0.00045 19.9 0.1 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 KEY74709.1 - 0.02 13.0 0.0 0.03 12.4 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 p450 PF00067.17 KEY74712.1 - 4.4e-45 154.0 0.0 5e-28 97.8 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 Epimerase PF01370.16 KEY74714.1 - 9.5e-19 67.7 0.1 1.4e-18 67.2 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY74714.1 - 2.4e-12 47.2 0.0 3.6e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KEY74714.1 - 9e-08 31.6 0.0 1.9e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 KEY74714.1 - 7.1e-05 21.6 0.0 0.00015 20.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KEY74714.1 - 0.00012 22.0 0.7 0.00023 21.1 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KEY74714.1 - 0.00036 19.5 0.1 0.58 8.9 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain AlaDh_PNT_C PF01262.16 KEY74714.1 - 0.066 12.7 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DapB_N PF01113.15 KEY74714.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Cas_csx3 PF09620.5 KEY74715.1 - 0.084 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) IDO PF01231.13 KEY74716.1 - 6e-11 41.4 0.2 2.5e-09 36.1 0.1 2.2 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase adh_short PF00106.20 KEY74718.1 - 8e-13 48.6 0.0 9.5e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY74718.1 - 7.5e-09 35.4 0.0 1.1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY74718.1 - 2.5e-07 30.3 0.0 3.4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KEY74718.1 - 7.1e-05 22.6 0.1 8.5e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RNA_pol_Rpb6 PF01192.17 KEY74718.1 - 0.0098 15.6 0.1 0.027 14.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb6 3HCDH_N PF02737.13 KEY74718.1 - 0.01 15.4 0.1 0.016 14.8 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KEY74718.1 - 0.03 13.2 0.0 0.036 12.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 KEY74718.1 - 0.05 12.6 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 KEY74718.1 - 0.17 12.0 0.5 0.85 9.7 0.1 2.3 1 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lyase_1 PF00206.15 KEY74719.1 - 0.05 12.7 0.1 0.31 10.1 0.0 1.9 2 0 0 2 2 2 0 Lyase Melibiase PF02065.13 KEY74720.1 - 3.3e-17 62.2 0.7 3.6e-14 52.2 0.5 2.3 1 1 0 1 1 1 1 Melibiase PMSR PF01625.16 KEY74720.1 - 0.041 13.7 0.2 0.069 13.0 0.1 1.3 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase Zn_clus PF00172.13 KEY74721.1 - 1e-06 28.5 9.4 1.7e-06 27.8 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEY74721.1 - 0.00015 20.5 0.5 0.00036 19.2 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain p450 PF00067.17 KEY74722.1 - 7.2e-53 179.7 0.0 9.5e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KEY74723.1 - 1.5e-33 116.0 29.0 1.5e-33 116.0 20.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily VCBS PF13517.1 KEY74724.1 - 0.02 15.2 1.0 0.02 15.2 0.7 4.6 4 2 2 6 6 6 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Ank_2 PF12796.2 KEY74727.1 - 5.3e-66 218.9 0.0 8.4e-20 70.9 0.0 4.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KEY74727.1 - 1.2e-59 195.2 0.0 1.5e-08 33.9 0.0 10.1 10 0 0 10 10 9 9 Ankyrin repeat Ank_4 PF13637.1 KEY74727.1 - 2.2e-43 145.8 5.0 1.7e-09 37.9 0.0 7.1 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY74727.1 - 4.6e-40 131.6 0.0 8.5e-06 25.5 0.0 10.2 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 KEY74727.1 - 5.1e-36 121.8 3.2 6e-09 35.8 0.0 6.8 5 1 2 7 7 7 6 Ankyrin repeats (many copies) RelA_SpoT PF04607.12 KEY74727.1 - 9.2e-09 35.3 0.0 2.6e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins NACHT PF05729.7 KEY74727.1 - 1.3e-08 34.6 0.0 4e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEY74727.1 - 1.3e-07 31.8 0.2 1.5e-06 28.3 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEY74727.1 - 2.5e-05 24.4 0.0 0.00016 21.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain Ribosomal_S6 PF01250.12 KEY74727.1 - 0.00013 21.7 0.0 8.6 6.2 0.0 5.2 2 1 3 6 6 6 0 Ribosomal protein S6 Shigella_OspC PF06128.6 KEY74727.1 - 0.00022 20.8 0.0 3.6 6.9 0.0 4.5 3 1 2 5 5 5 1 Shigella flexneri OspC protein Arch_ATPase PF01637.13 KEY74727.1 - 0.00054 19.7 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase KAP_NTPase PF07693.9 KEY74727.1 - 0.0033 16.4 0.8 0.066 12.1 0.1 2.9 3 1 1 4 4 4 1 KAP family P-loop domain PH_8 PF15409.1 KEY74727.1 - 0.011 15.7 0.1 50 4.0 0.0 4.8 2 1 3 5 5 5 0 Pleckstrin homology domain DUF2075 PF09848.4 KEY74727.1 - 0.033 13.1 0.2 2.2 7.1 0.0 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 KEY74727.1 - 0.035 13.5 0.0 0.1 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 KEY74727.1 - 0.06 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 KEY74727.1 - 0.097 12.4 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Beta-lactamase PF00144.19 KEY74729.1 - 1.8e-36 125.8 0.1 2.9e-36 125.1 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Pkinase PF00069.20 KEY74730.1 - 8.7e-25 87.3 0.0 1.5e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY74730.1 - 4.2e-07 29.2 0.0 8e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEY74730.1 - 0.00011 22.0 0.1 0.034 13.8 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Glyco_hydro_31 PF01055.21 KEY74731.1 - 5.8e-133 443.9 4.8 7.1e-133 443.6 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KEY74731.1 - 8.5e-05 22.3 1.8 0.00037 20.2 0.1 2.8 3 1 0 3 3 3 1 Galactose mutarotase-like Fungal_trans_2 PF11951.3 KEY74732.1 - 1.7e-07 30.1 1.4 3.8e-07 29.0 0.5 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain PEP_mutase PF13714.1 KEY74734.1 - 6.9e-58 195.6 4.6 7.8e-58 195.4 3.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KEY74734.1 - 0.12 10.5 0.1 0.16 10.1 0.0 1.2 1 0 0 1 1 1 0 Isocitrate lyase family Tyrosinase PF00264.15 KEY74735.1 - 2.1e-37 129.4 2.5 2.8e-37 129.0 1.7 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Period_C PF12114.3 KEY74736.1 - 0.16 11.5 4.3 0.19 11.3 3.0 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region HPHLAWLY PF14925.1 KEY74736.1 - 1.1 7.1 6.0 1.2 7.0 4.1 1.0 1 0 0 1 1 1 0 Domain of unknown function CFEM PF05730.6 KEY74738.1 - 4.6e-12 45.5 7.2 7.6e-12 44.8 5.0 1.4 1 0 0 1 1 1 1 CFEM domain DUF808 PF05661.7 KEY74738.1 - 1.7 7.4 6.4 0.83 8.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF808) GST_N_3 PF13417.1 KEY74739.1 - 4.8e-10 39.5 0.0 9.4e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEY74739.1 - 4.1e-08 33.1 0.0 7.5e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEY74739.1 - 4.5e-05 23.2 0.6 7.3e-05 22.5 0.4 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KEY74739.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HET PF06985.6 KEY74740.1 - 5e-18 65.6 0.0 1.3e-17 64.2 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF987 PF06174.6 KEY74740.1 - 0.024 14.1 0.0 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF987) DUF4131 PF13567.1 KEY74741.1 - 0.17 11.2 3.0 0.9 8.9 0.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF4389 PF14333.1 KEY74741.1 - 0.34 10.6 4.3 0.34 10.6 0.2 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4389) DUF1469 PF07332.6 KEY74741.1 - 8.1 6.2 10.3 0.93 9.2 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) CFEM PF05730.6 KEY74742.1 - 0.00064 19.4 5.2 0.00064 19.4 3.6 2.4 2 0 0 2 2 2 1 CFEM domain ABC2_membrane_4 PF12730.2 KEY74743.1 - 0.44 9.6 16.0 0.13 11.4 7.2 2.3 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF805 PF05656.9 KEY74743.1 - 1.9 8.3 14.1 0.098 12.4 2.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF805) APH PF01636.18 KEY74745.1 - 5.5e-10 39.3 0.1 7.7e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEY74745.1 - 0.007 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fungal_trans_2 PF11951.3 KEY74747.1 - 0.0049 15.5 1.7 0.0076 14.8 1.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY74747.1 - 0.089 12.7 7.4 0.17 11.8 5.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_1 PF00190.17 KEY74748.1 - 1.7e-10 40.4 0.0 2.2e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 KEY74748.1 - 1.7e-05 24.2 0.0 4.8e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Cupin domain ABC2_membrane PF01061.19 KEY74751.1 - 2.7e-85 284.7 58.1 1.5e-44 151.7 18.8 3.2 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 KEY74751.1 - 1.2e-34 119.5 1.1 1.6e-17 64.0 0.0 2.6 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 KEY74751.1 - 2.3e-31 107.5 11.7 3.4e-27 94.1 0.0 2.9 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KEY74751.1 - 2.5e-16 59.5 0.0 5.5e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_16 PF13191.1 KEY74751.1 - 5e-08 33.1 0.1 5.8e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 KEY74751.1 - 7.4e-08 32.0 0.1 6.7e-05 22.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KEY74751.1 - 4.3e-06 26.6 0.3 0.00052 19.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KEY74751.1 - 7.1e-06 25.3 0.1 0.0029 16.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KEY74751.1 - 6.2e-05 22.4 3.2 0.0022 17.4 0.5 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 KEY74751.1 - 0.00026 20.4 1.9 0.0046 16.4 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 KEY74751.1 - 0.00098 19.4 0.1 0.012 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEY74751.1 - 0.0011 19.0 0.6 0.28 11.3 0.1 2.8 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 KEY74751.1 - 0.0016 18.1 1.3 0.21 11.2 0.1 2.6 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.18 KEY74751.1 - 0.0047 16.8 0.0 4.3 7.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.1 KEY74751.1 - 0.011 15.2 0.3 0.49 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KEY74751.1 - 0.021 15.6 0.0 0.16 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 KEY74751.1 - 0.022 14.7 0.0 0.34 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KEY74751.1 - 0.035 14.4 0.0 0.099 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KEY74751.1 - 0.048 13.6 0.9 0.17 11.8 0.2 2.1 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KEY74751.1 - 0.052 12.7 0.1 10 5.2 0.0 2.6 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.7 KEY74751.1 - 0.069 12.2 0.4 0.42 9.6 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin Miro PF08477.8 KEY74751.1 - 0.1 13.1 0.1 4.4 7.8 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 KEY74751.1 - 0.17 11.2 0.9 6.8 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain Viral_helicase1 PF01443.13 KEY74751.1 - 0.18 11.2 0.2 12 5.3 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_15 PF13175.1 KEY74751.1 - 0.22 10.5 0.0 0.5 9.3 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 KEY74751.1 - 0.34 10.3 1.5 1 8.8 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 KEY74751.1 - 0.38 10.3 2.4 0.59 9.7 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PDR_assoc PF08370.6 KEY74751.1 - 4.8 6.7 9.0 0.088 12.3 0.2 2.5 2 0 0 2 2 1 0 Plant PDR ABC transporter associated Glycos_transf_1 PF00534.15 KEY74752.1 - 6.1e-16 58.3 0.0 1.3e-15 57.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KEY74752.1 - 8.4e-09 35.6 0.0 3.7e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KEY74752.1 - 0.00059 20.0 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Sugar_tr PF00083.19 KEY74753.1 - 2.7e-82 276.7 23.8 3.2e-82 276.5 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY74753.1 - 2e-28 99.1 52.6 2.2e-27 95.6 19.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TAT_signal PF10518.4 KEY74753.1 - 0.54 10.4 0.1 0.54 10.4 0.0 3.7 4 0 0 4 4 4 0 TAT (twin-arginine translocation) pathway signal sequence Glyco_hydro_3 PF00933.16 KEY74754.1 - 4.8e-81 272.0 0.0 1.8e-80 270.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY74754.1 - 1.6e-63 214.3 0.0 6.8e-63 212.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEY74754.1 - 1.6e-13 50.3 0.0 4.4e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KEY74754.1 - 3.4e-11 43.0 0.0 5.6e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 PA14 domain FAD-SLDH PF12318.3 KEY74754.1 - 0.18 11.4 0.0 4.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase FAD_binding_3 PF01494.14 KEY74755.1 - 1.5e-08 34.1 2.4 0.002 17.2 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_3 PF13738.1 KEY74755.1 - 0.019 14.9 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY74755.1 - 0.027 14.4 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.5 KEY74755.1 - 0.1 11.3 0.0 8.8 5.0 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase Peptidase_M20 PF01546.23 KEY74756.1 - 9.2e-26 90.5 0.1 1.2e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KEY74756.1 - 0.02 14.6 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 Peptidase dimerisation domain Nairovirus_M PF07948.6 KEY74756.1 - 0.12 10.5 0.0 0.16 10.0 0.0 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like Fungal_trans PF04082.13 KEY74757.1 - 2e-19 69.4 5.9 4.8e-19 68.2 4.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY74757.1 - 0.00082 19.2 1.9 0.0016 18.2 1.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldolase_II PF00596.16 KEY74758.1 - 2.1e-51 174.1 0.2 2.5e-51 173.9 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain 2-Hacid_dh_C PF02826.14 KEY74759.1 - 8.3e-40 135.8 0.0 1.2e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KEY74759.1 - 9.2e-24 83.4 0.0 1.2e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 KEY74759.1 - 0.018 15.4 0.8 0.16 12.4 0.4 2.5 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.16 KEY74759.1 - 0.021 14.6 0.8 0.082 12.7 0.2 2.2 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 KEY74759.1 - 0.027 13.8 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NmrA PF05368.8 KEY74760.1 - 6.4e-25 87.7 0.0 8.3e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY74760.1 - 2.2e-08 34.3 0.2 3.2e-08 33.7 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEY74760.1 - 6.6e-07 29.0 0.1 8.1e-05 22.1 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KEY74760.1 - 9.2e-06 25.9 0.1 2.9e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KEY74760.1 - 0.00019 20.2 0.1 0.00029 19.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KEY74760.1 - 0.0008 19.1 0.1 0.0076 15.9 0.0 2.1 2 0 0 2 2 2 1 KR domain Saccharop_dh PF03435.13 KEY74760.1 - 0.012 14.6 0.2 0.022 13.7 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase TrkA_N PF02254.13 KEY74760.1 - 0.028 14.4 0.0 0.07 13.1 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain LigB PF02900.13 KEY74761.1 - 1.1e-42 145.9 0.0 1.6e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Peptidase_M24 PF00557.19 KEY74761.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase family M24 Zn_clus PF00172.13 KEY74762.1 - 1.1e-10 41.2 9.6 1.8e-10 40.5 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.5 KEY74762.1 - 0.15 12.2 5.0 0.74 9.9 1.1 2.2 2 0 0 2 2 2 0 Opy2 protein Fungal_trans PF04082.13 KEY74763.1 - 1.5e-12 46.9 0.0 2e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_23 PF13489.1 KEY74764.1 - 0.0019 17.9 0.0 0.0019 17.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY74764.1 - 0.043 13.3 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KEY74764.1 - 0.045 14.2 0.0 0.057 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF676 PF05057.9 KEY74765.1 - 0.00045 19.5 0.0 0.00076 18.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) CorA PF01544.13 KEY74766.1 - 1.1e-09 37.7 0.0 1.7e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Beta_helix PF13229.1 KEY74770.1 - 0.00041 20.1 14.0 0.00041 20.1 9.7 2.4 1 1 1 2 2 2 2 Right handed beta helix region Na_H_Exchanger PF00999.16 KEY74771.1 - 1.6e-41 142.1 25.8 2.2e-41 141.6 17.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family HCO3_cotransp PF00955.16 KEY74772.1 - 2.7e-42 145.1 19.5 2.5e-20 72.6 2.9 4.1 3 1 1 4 4 4 4 HCO3- transporter family Herpes_US9 PF06072.6 KEY74772.1 - 0.071 12.9 0.5 0.21 11.4 0.3 1.8 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 SET PF00856.23 KEY74773.1 - 1.2e-09 38.6 0.0 2.7e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 SET domain Glyco_transf_34 PF05637.7 KEY74774.1 - 3e-10 40.0 0.0 6.4e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family MFS_1 PF07690.11 KEY74775.1 - 3.1e-31 108.3 27.8 4.4e-31 107.8 19.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DHDPS PF00701.17 KEY74776.1 - 2e-40 138.2 0.0 2.3e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Zn_clus PF00172.13 KEY74777.1 - 3.4e-08 33.2 8.2 7.7e-08 32.1 5.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY74777.1 - 0.00022 20.2 2.6 0.03 13.2 1.7 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain Transpos_assoc PF13963.1 KEY74777.1 - 0.072 13.0 1.8 0.16 11.9 1.2 1.6 1 0 0 1 1 1 0 Transposase-associated domain SnoaL_2 PF12680.2 KEY74778.1 - 0.1 13.0 0.4 0.15 12.5 0.3 1.4 1 0 0 1 1 1 0 SnoaL-like domain Ferric_reduct PF01794.14 KEY74779.1 - 5.6e-12 45.8 19.3 5.6e-12 45.8 13.4 2.5 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KEY74779.1 - 2.3e-07 30.6 0.0 2.4e-05 24.1 0.0 2.7 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 KEY74779.1 - 2.9e-06 27.2 1.5 0.059 13.2 0.0 2.6 1 1 1 2 2 2 2 Ferric reductase NAD binding domain ketoacyl-synt PF00109.21 KEY74780.1 - 3.3e-56 190.5 0.2 2.4e-52 177.9 0.1 2.6 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KEY74780.1 - 6.5e-40 135.6 0.3 1.3e-39 134.7 0.2 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain p450 PF00067.17 KEY74780.1 - 5.5e-11 41.6 0.0 8.5e-11 41.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Thiolase_N PF00108.18 KEY74780.1 - 0.03 13.3 0.1 0.065 12.2 0.0 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain DUF1857 PF08982.6 KEY74781.1 - 3.5e-13 49.3 0.0 3.7e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Glyco_transf_28 PF03033.15 KEY74782.1 - 5.9e-23 81.1 0.0 1.5e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KEY74782.1 - 3.4e-06 25.9 0.1 5.8e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KEY74782.1 - 0.0029 17.3 0.0 0.0062 16.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain RTA1 PF04479.8 KEY74783.1 - 8.8e-51 172.5 5.3 9.5e-51 172.4 3.6 1.0 1 0 0 1 1 1 1 RTA1 like protein Kei1 PF08552.6 KEY74783.1 - 0.046 13.3 0.3 0.046 13.3 0.2 1.7 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Glyco_hydro_10 PF00331.15 KEY74784.1 - 4.6e-20 71.8 0.0 1.9e-07 30.4 0.0 3.0 2 1 1 3 3 3 3 Glycosyl hydrolase family 10 Glyco_hydro_61 PF03443.9 KEY74785.1 - 1.3e-45 155.8 0.1 1.6e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Abhydrolase_4 PF08386.5 KEY74786.1 - 3e-19 68.8 0.0 6.5e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KEY74786.1 - 1.3e-14 54.3 0.0 2.4e-13 50.1 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEY74786.1 - 9.8e-08 32.1 0.2 4.2e-07 30.0 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY74786.1 - 0.00056 19.6 0.0 0.01 15.5 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PAP2 PF01569.16 KEY74787.1 - 1.4e-19 70.0 0.0 3e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 PAP2 superfamily TPR_12 PF13424.1 KEY74788.1 - 2.1e-16 59.5 0.1 2e-09 37.2 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEY74788.1 - 5.5e-12 44.7 2.5 4.1e-06 26.1 0.4 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 KEY74788.1 - 3.1e-10 39.6 2.7 2.6e-05 23.9 0.2 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEY74788.1 - 4.2e-10 39.1 5.6 5.2e-07 29.2 0.5 2.0 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KEY74788.1 - 9.2e-10 37.6 1.0 0.00047 19.8 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEY74788.1 - 8.9e-09 34.5 0.2 0.0028 17.3 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEY74788.1 - 1.2e-07 30.9 0.8 0.0019 17.8 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEY74788.1 - 2.6e-06 27.5 0.5 0.0023 18.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 KEY74788.1 - 1.1e-05 25.3 0.1 0.64 10.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEY74788.1 - 1.2e-05 25.8 1.4 3.1e-05 24.5 1.0 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEY74788.1 - 0.0001 22.2 0.6 0.37 11.1 0.0 3.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEY74788.1 - 0.0018 18.6 1.6 0.21 12.1 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat PPR PF01535.15 KEY74788.1 - 0.033 14.1 0.3 5.6 7.1 0.0 3.0 2 1 1 3 3 3 0 PPR repeat RPN7 PF10602.4 KEY74788.1 - 0.059 12.7 0.1 3.4 6.9 0.0 2.3 3 0 0 3 3 3 0 26S proteasome subunit RPN7 DUF3366 PF11846.3 KEY74788.1 - 0.074 12.9 0.1 6.8 6.5 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3366) Sel1 PF08238.7 KEY74788.1 - 0.17 12.5 2.5 6 7.6 0.0 2.5 2 0 0 2 2 2 0 Sel1 repeat TPR_12 PF13424.1 KEY74789.1 - 3.6e-113 369.6 6.8 3.5e-18 65.3 0.0 6.9 2 2 7 9 9 9 9 Tetratricopeptide repeat TPR_10 PF13374.1 KEY74789.1 - 1.9e-107 348.5 1.4 1.7e-11 43.6 0.0 10.7 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_7 PF13176.1 KEY74789.1 - 2.6e-45 148.6 8.6 0.00071 19.1 0.0 9.7 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 KEY74789.1 - 1.1e-29 99.8 6.9 0.099 12.6 0.0 9.9 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.23 KEY74789.1 - 1.1e-25 88.0 2.3 0.25 11.0 0.0 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_4 PF07721.9 KEY74789.1 - 2.1e-23 80.2 0.4 0.36 11.3 0.0 10.5 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 KEY74789.1 - 3e-23 81.8 0.6 0.00056 20.5 0.0 6.9 5 2 2 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 KEY74789.1 - 5.9e-23 81.0 4.3 0.0043 17.3 0.0 9.5 2 1 8 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.1 KEY74789.1 - 6.2e-23 80.2 5.2 0.00022 20.7 0.0 6.0 3 2 4 7 7 7 6 TPR repeat TPR_17 PF13431.1 KEY74789.1 - 4.8e-22 76.2 11.4 0.33 11.2 0.0 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_14 PF13428.1 KEY74789.1 - 6.5e-21 72.9 11.4 0.97 10.2 0.0 11.0 10 2 2 12 12 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 KEY74789.1 - 8.9e-19 65.8 4.7 2.4 8.1 0.0 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat Apc3 PF12895.2 KEY74789.1 - 6.2e-16 58.3 0.2 0.0037 17.3 0.0 5.6 1 1 5 7 7 7 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KEY74789.1 - 7.9e-15 54.2 18.8 2.5 8.7 0.1 10.5 11 0 0 11 11 10 4 Tetratricopeptide repeat PPR PF01535.15 KEY74789.1 - 8.2e-12 44.2 3.0 14 5.8 0.0 8.6 8 0 0 8 8 8 0 PPR repeat DUF4074 PF13293.1 KEY74789.1 - 4.6e-10 39.5 4.4 27 5.0 0.0 8.1 8 0 0 8 8 8 0 Domain of unknown function (DUF4074) TPR_5 PF12688.2 KEY74789.1 - 5.6e-09 36.0 0.9 12 5.9 0.0 7.1 1 1 7 8 8 8 0 Tetratrico peptide repeat TPR_20 PF14561.1 KEY74789.1 - 7.9e-09 35.5 0.7 5.2 7.2 0.0 7.6 1 1 7 8 8 8 1 Tetratricopeptide repeat PPR_3 PF13812.1 KEY74789.1 - 2.4e-08 33.6 7.9 18 5.9 0.0 8.5 8 0 0 8 8 8 0 Pentatricopeptide repeat domain NACHT PF05729.7 KEY74789.1 - 2.4e-06 27.2 0.0 4.8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Rab5-bind PF09311.6 KEY74789.1 - 8.3e-06 25.8 6.9 1.8 8.4 0.2 6.7 1 1 7 8 8 8 1 Rabaptin-like protein NB-ARC PF00931.17 KEY74789.1 - 0.00018 20.4 0.0 0.051 12.4 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain TPR_3 PF07720.7 KEY74789.1 - 0.00035 20.3 0.0 69 3.3 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF2518 PF10726.4 KEY74789.1 - 0.0057 16.1 0.1 37 3.8 0.0 4.7 2 2 5 7 7 7 0 Protein of function (DUF2518) AAA_25 PF13481.1 KEY74789.1 - 0.0098 15.3 0.0 0.039 13.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEY74789.1 - 0.01 15.9 0.0 0.029 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain RBD-FIP PF09457.5 KEY74789.1 - 0.069 12.9 4.0 73 3.2 0.0 4.8 5 0 0 5 5 4 0 FIP domain DUF4363 PF14276.1 KEY74789.1 - 5.7 6.6 17.8 58 3.4 0.1 6.2 7 1 0 7 7 7 0 Domain of unknown function (DUF4363) DnaJ PF00226.26 KEY74790.1 - 1.1e-16 60.3 0.1 1.5e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain DDE_1 PF03184.14 KEY74791.1 - 9.6e-21 73.9 0.0 1.3e-19 70.2 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 KEY74791.1 - 3.4e-06 26.7 0.0 1e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 KEY74791.1 - 0.00015 21.2 0.0 0.00044 19.7 0.0 1.9 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Syntaxin-6_N PF09177.6 KEY74791.1 - 0.046 14.1 2.0 0.23 11.8 0.1 2.7 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Allexi_40kDa PF05549.6 KEY74791.1 - 0.23 10.7 3.0 7.4 5.7 0.3 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein ADIP PF11559.3 KEY74791.1 - 0.86 9.5 4.7 0.95 9.3 0.2 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 KEY74791.1 - 3.5 6.4 8.6 8.1 5.2 0.3 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3359 PF11839.3 KEY74791.1 - 4.8 7.5 6.5 25 5.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3359) FAD_binding_4 PF01565.18 KEY74794.1 - 1.9e-11 43.6 0.2 2.8e-11 43.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain HPS3_N PF14761.1 KEY74794.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 ADH_zinc_N PF00107.21 KEY74795.1 - 5.6e-15 55.0 0.0 8.7e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY74795.1 - 2.7e-05 23.8 0.1 5.7e-05 22.8 0.1 1.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KEY74795.1 - 0.13 13.2 0.0 0.23 12.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Abhydrolase_5 PF12695.2 KEY74796.1 - 0.036 13.8 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3328 PF11807.3 KEY74797.1 - 1.2e-29 103.5 0.0 1.5e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Corona_nucleoca PF00937.13 KEY74798.1 - 0.018 14.0 1.7 0.02 13.8 1.2 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF3645 PF12359.3 KEY74798.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3645) Glyco_hydro_11 PF00457.12 KEY74799.1 - 4.6e-50 169.4 3.2 6e-50 169.1 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Glyco_hydro_7 PF00840.15 KEY74800.1 - 4.6e-139 463.5 3.6 6.1e-139 463.1 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Peptidase_C65 PF10275.4 KEY74800.1 - 0.21 10.9 0.7 0.32 10.3 0.5 1.2 1 0 0 1 1 1 0 Peptidase C65 Otubain Cyt-b5 PF00173.23 KEY74801.1 - 2.2e-14 53.0 0.0 1.3e-13 50.5 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IDO PF01231.13 KEY74801.1 - 3.6e-10 38.8 0.0 2.5e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 Indoleamine 2,3-dioxygenase FAD_binding_1 PF00667.15 KEY74801.1 - 7.1e-10 38.6 0.0 3.6e-09 36.3 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KEY74801.1 - 2.1e-07 31.4 0.0 5.3e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain SNF2_assoc PF08455.5 KEY74801.1 - 1.5 7.3 0.0 2.3 6.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial SNF2 helicase associated ketoacyl-synt PF00109.21 KEY74802.1 - 1.5e-76 257.2 0.0 5.8e-76 255.3 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEY74802.1 - 2.9e-41 141.8 0.0 6.6e-41 140.6 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KEY74802.1 - 5.4e-27 94.0 0.1 1.1e-26 93.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KEY74802.1 - 1.2e-22 79.9 5.6 1.4e-10 41.2 0.3 3.0 3 0 0 3 3 3 2 Phosphopantetheine attachment site NAD_binding_4 PF07993.7 KEY74802.1 - 1.6e-20 73.1 0.0 2.6e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Thiolase_N PF00108.18 KEY74802.1 - 2.9e-05 23.2 0.0 5.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 KEY74802.1 - 0.00022 21.0 0.0 0.028 14.1 0.0 3.2 3 0 0 3 3 3 1 Alpha/beta hydrolase family adh_short PF00106.20 KEY74802.1 - 0.0017 18.2 0.0 0.0053 16.6 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KEY74802.1 - 0.03 13.2 0.0 0.1 11.4 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF915 PF06028.6 KEY74802.1 - 0.073 12.1 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Epimerase PF01370.16 KEY74802.1 - 0.08 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ketoacyl-synt PF00109.21 KEY74803.1 - 4.5e-77 258.9 0.0 7.5e-77 258.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KEY74803.1 - 8.1e-58 195.0 0.1 1.9e-57 193.8 0.1 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KEY74803.1 - 1.2e-48 165.8 0.0 1.9e-48 165.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KEY74803.1 - 8.3e-47 160.0 0.0 1.4e-46 159.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KEY74803.1 - 3e-43 147.6 0.1 8.3e-43 146.1 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KEY74803.1 - 1.7e-38 131.0 0.5 1.7e-38 131.0 0.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KEY74803.1 - 1.7e-20 72.9 0.0 1.4e-19 69.8 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY74803.1 - 5e-11 43.5 0.0 1.9e-10 41.7 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY74803.1 - 0.00024 20.8 0.2 0.00074 19.2 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KEY74803.1 - 0.00027 21.1 0.1 0.0033 17.6 0.0 2.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KEY74803.1 - 0.00041 19.4 0.0 0.00082 18.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Fungal_trans_2 PF11951.3 KEY74804.1 - 7.3e-06 24.8 0.2 2e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.20 KEY74805.1 - 1e-17 64.5 0.8 2.5e-17 63.2 0.4 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY74805.1 - 1.8e-09 37.4 0.2 3.6e-09 36.5 0.2 1.4 1 0 0 1 1 1 1 KR domain Sperm_Ag_HE2 PF05324.8 KEY74805.1 - 0.007 16.2 0.5 1.8 8.5 0.0 2.3 2 0 0 2 2 2 2 Sperm antigen HE2 MFS_1 PF07690.11 KEY74806.1 - 1.3e-45 155.7 29.1 1.3e-45 155.7 20.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily SnoaL_4 PF13577.1 KEY74807.1 - 6.3e-13 48.7 0.4 7.8e-13 48.4 0.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 KEY74807.1 - 0.0084 16.4 0.1 0.015 15.6 0.1 1.5 1 1 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.2 KEY74807.1 - 0.016 15.7 0.1 0.03 14.8 0.0 1.4 1 1 0 1 1 1 0 Putative lumazine-binding DUF4440 PF14534.1 KEY74807.1 - 0.029 14.5 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) AflR PF08493.5 KEY74808.1 - 0.0009 18.3 5.6 0.0014 17.7 3.9 1.2 1 0 0 1 1 1 1 Aflatoxin regulatory protein Herpes_capsid PF06112.6 KEY74808.1 - 2.3 8.2 6.9 5.1 7.1 4.8 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein p450 PF00067.17 KEY74809.1 - 2e-74 250.7 0.1 2.5e-74 250.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4243 PF14027.1 KEY74810.1 - 1.2e-79 268.1 0.1 1.4e-79 267.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) FAD_binding_3 PF01494.14 KEY74811.1 - 1.5e-75 254.4 0.0 2.2e-75 253.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEY74811.1 - 9.2e-11 41.2 0.3 3.7e-05 22.8 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEY74811.1 - 0.00014 22.1 0.3 0.0011 19.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEY74811.1 - 0.00018 21.4 0.4 0.00042 20.2 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEY74811.1 - 0.00054 18.9 0.6 0.0011 17.8 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KEY74811.1 - 0.00074 19.4 0.1 0.0018 18.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEY74811.1 - 0.0015 18.6 0.1 0.0041 17.1 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEY74811.1 - 0.0017 17.5 0.5 0.004 16.2 0.3 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KEY74811.1 - 0.0033 16.5 0.0 0.0075 15.3 0.0 1.5 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KEY74811.1 - 0.035 12.5 0.2 0.058 11.8 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_7 PF13241.1 KEY74811.1 - 0.059 13.6 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Fungal_trans PF04082.13 KEY74812.1 - 8.6e-18 64.1 0.4 1.5e-17 63.3 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Daxx PF03344.10 KEY74812.1 - 0.26 9.7 1.2 0.39 9.1 0.8 1.1 1 0 0 1 1 1 0 Daxx Family adh_short PF00106.20 KEY74813.1 - 1e-13 51.5 0.0 1.8e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY74813.1 - 1.7e-09 37.6 0.0 2.8e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Glyco_hydro_10 PF00331.15 KEY74814.1 - 6e-96 321.2 0.3 6.9e-96 321.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_1 PF00232.13 KEY74814.1 - 0.032 12.4 1.1 0.061 11.5 0.1 1.9 3 0 0 3 3 3 0 Glycosyl hydrolase family 1 Frankia_peptide PF14407.1 KEY74814.1 - 0.047 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. PhyH PF05721.8 KEY74815.1 - 3e-07 30.6 0.0 1.7e-06 28.2 0.0 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF2346 PF09803.4 KEY74815.1 - 0.095 12.5 0.1 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) Prim_Zn_Ribbon PF08273.7 KEY74815.1 - 0.36 10.9 1.7 2.2 8.3 0.0 2.5 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Zn_clus PF00172.13 KEY74816.1 - 3e-08 33.4 9.1 5.7e-08 32.5 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.1 KEY74817.1 - 8.2e-09 35.2 26.8 8.8e-05 22.3 1.0 7.5 7 1 1 8 8 8 2 Tetratricopeptide repeat NACHT PF05729.7 KEY74817.1 - 0.00012 21.7 0.0 0.00038 20.1 0.0 1.9 1 0 0 1 1 1 1 NACHT domain TPR_7 PF13176.1 KEY74817.1 - 0.00016 21.2 7.0 0.44 10.4 0.5 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat AAA_22 PF13401.1 KEY74817.1 - 0.00017 21.6 0.0 0.0011 19.1 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEY74817.1 - 0.00025 21.0 0.2 0.0011 18.9 0.1 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KEY74817.1 - 0.0029 18.4 0.1 0.12 13.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 KEY74817.1 - 0.0035 17.6 0.0 0.018 15.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain TPR_10 PF13374.1 KEY74817.1 - 0.014 15.2 18.0 0.92 9.5 0.0 5.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.1 KEY74817.1 - 0.14 12.5 10.1 48 4.3 0.2 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEY74817.1 - 0.2 12.3 16.4 31 5.5 0.6 8.5 8 1 1 9 9 9 0 Tetratricopeptide repeat Transferase PF02458.10 KEY74818.1 - 0.006 15.0 0.0 0.19 10.0 0.0 2.1 2 0 0 2 2 2 2 Transferase family ketoacyl-synt PF00109.21 KEY74819.1 - 4.2e-77 259.0 0.1 1.1e-76 257.7 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Carn_acyltransf PF00755.15 KEY74819.1 - 3.2e-65 220.3 0.0 4.3e-65 219.9 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Acyl_transf_1 PF00698.16 KEY74819.1 - 6.7e-58 196.5 1.5 1.1e-57 195.7 1.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KEY74819.1 - 2.8e-46 157.4 0.0 1.5e-45 155.0 0.0 2.2 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KEY74819.1 - 1.2e-38 132.6 0.4 1.1e-37 129.4 0.0 2.8 3 0 0 3 3 3 1 short chain dehydrogenase PS-DH PF14765.1 KEY74819.1 - 3.9e-38 131.3 0.0 1.2e-37 129.6 0.0 1.9 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KEY74819.1 - 9e-36 122.3 0.1 2.7e-35 120.7 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KEY74819.1 - 2.5e-16 59.9 0.0 9e-16 58.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KEY74819.1 - 2.8e-15 55.9 0.0 4.1e-14 52.2 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEY74819.1 - 5.2e-15 56.4 0.0 1.9e-13 51.3 0.0 3.8 4 0 0 4 4 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KEY74819.1 - 4.1e-11 42.8 0.0 9.4e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY74819.1 - 3.5e-08 33.8 0.0 1.7e-07 31.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY74819.1 - 2.9e-06 26.9 0.0 7.1e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KEY74819.1 - 1.4e-05 25.2 0.6 5.7e-05 23.2 0.1 2.4 2 0 0 2 2 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 KEY74819.1 - 1.6e-05 24.6 0.7 3.7e-05 23.4 0.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 KEY74819.1 - 1.9e-05 25.1 0.0 8.7e-05 23.0 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEY74819.1 - 0.002 17.3 0.0 0.006 15.7 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Bt_P21 PF05560.6 KEY74819.1 - 0.3 10.4 0.0 0.65 9.3 0.0 1.4 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Pkinase PF00069.20 KEY74820.1 - 3.8e-60 203.2 0.0 4.9e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY74820.1 - 2e-31 108.9 0.0 2.7e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEY74820.1 - 0.00047 19.9 0.1 0.1 12.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KEY74820.1 - 0.0016 17.4 0.0 0.0028 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 KEY74820.1 - 0.048 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 KEY74820.1 - 0.11 11.6 0.0 0.45 9.5 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KEY74820.1 - 0.11 11.7 0.0 0.28 10.5 0.0 1.6 1 1 0 1 1 1 0 RIO1 family E1-E2_ATPase PF00122.15 KEY74821.1 - 6.4e-67 224.9 2.0 6.4e-67 224.9 1.4 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEY74821.1 - 6.8e-33 113.7 7.2 6.8e-33 113.7 5.0 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEY74821.1 - 2.5e-31 109.7 0.0 1.1e-29 104.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEY74821.1 - 2.1e-18 65.5 0.0 2.1e-18 65.5 0.0 2.2 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KEY74821.1 - 1.1e-17 63.7 0.0 2.8e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEY74821.1 - 2.3e-16 60.5 0.0 5.5e-16 59.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEY74821.1 - 4.2e-05 23.2 0.1 0.0023 17.5 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Myb_DNA-binding PF00249.26 KEY74822.1 - 7.2e-10 38.7 0.7 7.1e-06 25.9 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEY74822.1 - 1.5e-09 37.7 0.2 0.0015 18.6 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Fungal_trans PF04082.13 KEY74823.1 - 2.3e-30 105.3 0.1 4.3e-30 104.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY74823.1 - 4.1e-11 42.5 12.6 7.2e-11 41.8 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo_endo_phos PF03372.18 KEY74824.1 - 6.8e-10 39.2 0.0 8.7e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family EF-hand_8 PF13833.1 KEY74824.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair Glyco_hydro_28 PF00295.12 KEY74826.1 - 2.8e-42 144.8 1.4 5.4e-42 143.8 1.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 BTB PF00651.26 KEY74827.1 - 0.0036 17.2 0.0 0.03 14.2 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain MFS_1 PF07690.11 KEY74828.1 - 1e-44 152.7 23.6 1e-44 152.7 16.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY74828.1 - 2.2e-13 49.5 7.1 2.2e-13 49.5 4.9 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KEY74828.1 - 1.4e-06 26.7 1.8 2.7e-06 25.9 1.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 KEY74828.1 - 0.0023 16.0 1.6 0.0023 16.0 1.1 3.0 3 1 1 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family DEAD PF00270.24 KEY74829.1 - 2.6e-17 62.8 0.0 5.2e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KEY74829.1 - 5.1e-09 36.2 0.0 1.5e-07 31.4 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KEY74829.1 - 7.1e-06 25.7 0.2 1.8e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 KEY74829.1 - 0.0038 16.4 0.0 0.0079 15.4 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DUF2939 PF11159.3 KEY74829.1 - 0.017 15.2 0.1 0.053 13.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) SPAM PF02090.10 KEY74829.1 - 0.22 11.5 2.1 1.3 9.0 0.4 2.4 2 0 0 2 2 2 0 Salmonella surface presentation of antigen gene type M protein NmrA PF05368.8 KEY74830.1 - 3.6e-18 65.6 0.0 4.4e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY74830.1 - 6.1e-15 55.6 0.0 9.1e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEY74830.1 - 4.4e-07 29.5 0.0 8.8e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KEY74830.1 - 0.00056 20.2 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KEY74830.1 - 0.0018 17.2 0.0 0.0056 15.6 0.0 1.7 1 1 1 2 2 2 1 Male sterility protein DapB_N PF01113.15 KEY74830.1 - 0.0045 16.9 0.0 0.0093 15.8 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 KEY74830.1 - 0.0095 16.4 0.9 0.025 15.1 0.3 2.0 2 1 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase ThiF PF00899.16 KEY74830.1 - 0.023 14.4 0.5 1.5 8.6 0.0 2.6 2 0 0 2 2 2 0 ThiF family Aminotran_3 PF00202.16 KEY74831.1 - 9.4e-51 172.6 0.1 5.2e-50 170.1 0.1 1.9 1 1 0 1 1 1 1 Aminotransferase class-III Fungal_trans_2 PF11951.3 KEY74832.1 - 2e-37 128.7 3.4 2.4e-37 128.4 2.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Borrelia_REV PF03978.8 KEY74832.1 - 0.086 12.5 0.0 3.8 7.2 0.0 2.8 3 0 0 3 3 3 0 Borrelia burgdorferi REV protein NmrA PF05368.8 KEY74833.1 - 2.3e-28 99.0 0.1 2.8e-28 98.7 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY74833.1 - 1.5e-16 60.9 0.0 2.2e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEY74833.1 - 0.00028 20.3 0.0 0.43 9.9 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KEY74833.1 - 0.1 11.4 0.0 0.56 9.0 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein Ank_2 PF12796.2 KEY74834.1 - 0.00045 20.5 0.0 0.015 15.6 0.0 3.1 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEY74834.1 - 0.022 15.2 2.1 11 6.7 0.0 4.6 4 1 0 4 4 4 0 Ankyrin repeats (many copies) Ank PF00023.25 KEY74834.1 - 0.13 12.1 0.9 17 5.4 0.0 3.9 4 1 0 4 4 4 0 Ankyrin repeat Filament PF00038.16 KEY74834.1 - 0.17 11.2 1.4 0.95 8.8 0.1 2.3 2 1 0 2 2 2 0 Intermediate filament protein Reo_sigmaC PF04582.7 KEY74834.1 - 0.31 10.1 4.2 3.8 6.5 0.6 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Dzip-like_N PF13815.1 KEY74835.1 - 0.2 11.4 0.4 2 8.2 0.1 2.1 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal CTP_transf_1 PF01148.15 KEY74835.1 - 6 6.4 10.6 1.6 8.3 0.2 2.1 2 0 0 2 2 2 0 Cytidylyltransferase family Fungal_trans_2 PF11951.3 KEY74837.1 - 3.2e-08 32.5 0.2 4.8e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY74837.1 - 5.8e-08 32.5 3.5 1.3e-07 31.3 2.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEM52 PF14979.1 KEY74837.1 - 0.016 15.0 0.1 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Transmembrane 52 Ldl_recept_a PF00057.13 KEY74837.1 - 0.17 11.8 1.7 0.38 10.7 1.1 1.5 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A Asp PF00026.18 KEY74838.1 - 1.9e-40 139.0 0.0 2.5e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KEY74838.1 - 3.1e-05 24.3 1.4 0.16 12.5 0.0 3.4 3 0 0 3 3 3 2 Aspartyl protease TAXi_N PF14543.1 KEY74838.1 - 0.0021 18.0 0.0 0.0053 16.7 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 KEY74838.1 - 0.031 14.1 0.0 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 KEY74838.1 - 0.14 12.1 0.0 0.45 10.4 0.0 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease MIP PF00230.15 KEY74839.1 - 6.1e-28 97.8 10.7 7.3e-28 97.5 7.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF1279 PF06916.8 KEY74839.1 - 0.016 15.5 0.3 0.035 14.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) RVT_3 PF13456.1 KEY74840.1 - 0.049 13.4 0.1 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like HET PF06985.6 KEY74841.1 - 6.1e-22 78.2 0.0 1.8e-21 76.7 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) TPR_12 PF13424.1 KEY74844.1 - 6.3e-41 138.1 0.3 8e-16 57.7 0.0 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 KEY74844.1 - 5.3e-40 134.2 1.0 1.3e-12 47.1 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 KEY74844.1 - 8.2e-15 53.3 0.5 0.002 17.7 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEY74844.1 - 5.8e-09 35.4 3.5 0.25 11.6 0.0 4.9 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEY74844.1 - 1.1e-07 31.2 0.1 0.22 11.5 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEY74844.1 - 1.4e-07 30.8 0.0 0.4 10.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEY74844.1 - 2.7e-07 30.1 0.6 0.00018 21.0 0.0 3.2 1 1 2 3 3 3 3 TPR repeat TPR_14 PF13428.1 KEY74844.1 - 7.3e-06 26.1 4.4 0.47 11.2 0.0 5.2 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEY74844.1 - 9.5e-06 26.1 0.0 0.0032 18.0 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 KEY74844.1 - 2.5e-05 24.2 2.7 8.2 7.1 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEY74844.1 - 6.5e-05 23.1 0.7 0.044 14.1 0.0 3.4 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEY74844.1 - 0.0001 21.8 0.7 2.8 7.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEY74844.1 - 0.0018 18.5 3.7 3.2 8.4 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat NB-ARC PF00931.17 KEY74844.1 - 0.013 14.3 0.8 0.37 9.5 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain Sipho_Gp157 PF05565.6 KEY74845.1 - 0.014 14.9 1.9 0.021 14.4 1.3 1.3 1 1 0 1 1 1 0 Siphovirus Gp157 ThuA PF06283.6 KEY74845.1 - 0.052 13.2 1.2 0.062 12.9 0.9 1.0 1 0 0 1 1 1 0 Trehalose utilisation Katanin_con80 PF13925.1 KEY74845.1 - 0.079 12.7 0.2 0.089 12.5 0.1 1.0 1 0 0 1 1 1 0 con80 domain of Katanin Dimer_Tnp_hAT PF05699.9 KEY74846.1 - 9.3e-22 76.4 0.2 1.6e-21 75.6 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF221 PF02714.10 KEY74850.1 - 1.9e-91 306.3 14.5 1.9e-91 306.3 10.0 2.2 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KEY74850.1 - 1.5e-36 125.3 1.6 1.5e-36 125.3 1.1 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KEY74850.1 - 2.2e-20 72.3 0.1 4.3e-20 71.3 0.1 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KEY74850.1 - 1.7e-10 41.2 0.9 4.1e-10 40.0 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF4064 PF13273.1 KEY74850.1 - 0.72 9.9 0.0 0.72 9.9 0.0 4.3 2 1 3 5 5 5 0 Protein of unknown function (DUF4064) DDE_Tnp_1_7 PF13843.1 KEY74852.1 - 4.4e-24 85.1 0.0 5.1e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 bZIP_1 PF00170.16 KEY74853.1 - 2.5e-10 40.1 7.2 5.9e-10 38.9 5.0 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KEY74853.1 - 3e-05 23.7 5.2 3e-05 23.7 3.6 2.2 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.12 KEY74853.1 - 0.011 16.0 3.7 0.011 16.0 2.5 2.1 1 1 0 1 1 1 0 bZIP Maf transcription factor CDK5_activator PF03261.10 KEY74853.1 - 0.51 9.6 5.9 0.64 9.2 4.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Zn_clus PF00172.13 KEY74854.1 - 0.0069 16.2 1.3 0.012 15.4 0.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 KEY74855.1 - 0.0013 18.9 18.7 1.4 9.4 0.0 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEY74855.1 - 0.0014 18.7 15.5 0.11 12.8 0.0 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KEY74855.1 - 0.0025 17.6 1.6 0.061 13.2 0.7 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger DUF629 PF04780.7 KEY74855.1 - 0.021 13.3 0.7 0.063 11.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF629) DUF230 PF03003.11 KEY74855.1 - 0.07 12.6 0.7 0.14 11.6 0.5 1.5 1 0 0 1 1 1 0 Poxvirus proteins of unknown function zf-TAZ PF02135.11 KEY74855.1 - 3.9 7.5 6.6 3.3 7.7 2.2 2.2 2 0 0 2 2 2 0 TAZ zinc finger zf-H2C2_5 PF13909.1 KEY74855.1 - 6.6 7.1 6.9 41 4.6 0.9 3.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Myb_DNA-bind_3 PF12776.2 KEY74856.1 - 8.8e-07 29.4 0.4 1.5e-06 28.6 0.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain PNP_UDP_1 PF01048.15 KEY74857.1 - 2.1e-12 46.5 0.3 4.7e-12 45.3 0.2 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily DUF4611 PF15387.1 KEY74858.1 - 0.0036 17.4 1.0 0.0048 17.0 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 KEY74858.1 - 0.0099 15.4 2.4 0.01 15.3 1.7 1.1 1 0 0 1 1 1 1 Nucleoplasmin Daxx PF03344.10 KEY74858.1 - 0.077 11.4 1.6 0.08 11.4 1.1 1.1 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 KEY74858.1 - 0.31 10.2 1.7 0.32 10.2 1.2 1.1 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 KEY74858.1 - 1.2 9.4 10.0 1.8 8.8 7.0 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Profilin PF00235.14 KEY74859.1 - 2e-27 95.7 1.3 1.5e-25 89.6 0.9 2.0 1 1 0 1 1 1 1 Profilin Got1 PF04178.7 KEY74860.1 - 4.4e-18 65.4 11.3 5.4e-18 65.2 7.8 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.6 KEY74860.1 - 0.59 9.0 7.7 0.75 8.7 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) YrhK PF14145.1 KEY74860.1 - 3.5 7.3 14.4 0.38 10.4 4.6 2.5 2 0 0 2 2 2 0 YrhK-like protein YL1_C PF08265.6 KEY74861.1 - 3.6e-17 61.6 0.0 5.8e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DASH_Dad4 PF08650.5 KEY74862.1 - 1.5e-27 95.3 5.7 1.6e-27 95.1 3.9 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.12 KEY74862.1 - 0.026 14.4 0.6 0.03 14.2 0.4 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor DASH_Dad1 PF08649.5 KEY74862.1 - 0.027 14.1 3.0 0.035 13.7 2.1 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad1 Biotin_carb_C PF02785.14 KEY74862.1 - 0.045 13.7 0.0 0.048 13.6 0.0 1.1 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain NPV_P10 PF05531.7 KEY74862.1 - 0.19 12.0 2.9 0.24 11.6 2.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Actin PF00022.14 KEY74863.1 - 4.6e-56 189.9 0.0 3.4e-33 114.6 0.0 2.2 2 0 0 2 2 2 2 Actin bZIP_1 PF00170.16 KEY74864.1 - 4.5e-07 29.7 12.8 6.1e-07 29.3 7.0 2.5 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KEY74864.1 - 0.33 10.7 10.7 6.2 6.7 4.4 2.6 1 1 1 2 2 2 0 Basic region leucine zipper TPR_10 PF13374.1 KEY74865.1 - 2.6e-67 220.9 0.0 1.9e-12 46.6 0.0 7.5 6 1 1 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.1 KEY74865.1 - 1.8e-58 194.3 0.0 3.6e-17 62.0 0.0 4.9 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 KEY74865.1 - 4.6e-21 72.8 4.6 0.0018 17.9 0.0 7.0 7 1 0 7 7 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 KEY74865.1 - 2.1e-14 52.9 0.1 5.6e-05 22.7 0.0 3.9 3 2 0 3 3 3 3 TPR repeat TPR_17 PF13431.1 KEY74865.1 - 2.8e-14 52.0 0.0 0.35 11.1 0.0 6.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEY74865.1 - 6.3e-13 47.5 1.0 0.44 10.5 0.0 7.1 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEY74865.1 - 1.4e-11 43.4 0.0 0.31 10.7 0.0 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEY74865.1 - 7.8e-08 31.5 1.1 3.5 7.6 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEY74865.1 - 8e-08 32.2 0.1 19 6.2 0.0 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 KEY74865.1 - 1.7e-07 30.9 0.0 31 5.3 0.0 6.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEY74865.1 - 3e-07 30.9 0.0 9.6 7.0 0.0 5.5 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 KEY74865.1 - 1.2e-06 28.7 0.0 0.94 9.8 0.0 4.7 2 2 2 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KEY74865.1 - 1.3e-06 28.4 0.0 0.11 12.6 0.0 4.1 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 DUF2664 PF10867.3 KEY74865.1 - 0.00027 21.4 1.1 48 4.6 0.0 5.4 6 0 0 6 6 5 0 Protein of unknown function (DUF2664) PPR PF01535.15 KEY74865.1 - 0.0045 16.8 4.4 21 5.3 0.1 5.8 7 0 0 7 7 6 0 PPR repeat TPR_3 PF07720.7 KEY74865.1 - 0.0045 16.7 0.0 39 4.1 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Citrate_ly_lig PF08218.6 KEY74865.1 - 0.024 14.1 0.2 15 5.0 0.0 3.7 2 1 1 4 4 4 0 Citrate lyase ligase C-terminal domain DNAJ_related PF12339.3 KEY74865.1 - 0.027 14.3 0.9 2.2 8.1 0.0 3.0 2 1 0 2 2 2 0 DNA-J related protein Chlorosome_CsmC PF11098.3 KEY74865.1 - 0.034 13.8 0.1 0.11 12.2 0.1 1.8 1 0 0 1 1 1 0 Chlorosome envelope protein C TPR_6 PF13174.1 KEY74865.1 - 0.061 13.8 4.9 1.5e+02 3.1 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat cwf21 PF08312.7 KEY74865.1 - 1.7 8.5 4.3 9.1 6.2 1.0 3.1 1 1 1 2 2 2 0 cwf21 domain DDE_Tnp_1_7 PF13843.1 KEY74866.1 - 1.3e-29 103.3 0.0 1.7e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 PNP_UDP_1 PF01048.15 KEY74867.1 - 4.1e-13 48.8 0.1 1.1e-12 47.4 0.1 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily DUF1541 PF07563.6 KEY74867.1 - 0.0021 17.7 0.1 0.0039 16.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1541) AAA_22 PF13401.1 KEY74867.1 - 0.0027 17.8 0.0 0.036 14.2 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KEY74867.1 - 0.018 15.0 0.0 0.086 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Pro_Al_protease PF02983.9 KEY74870.1 - 0.01 15.7 0.2 0.01 15.7 0.1 2.5 2 1 0 2 2 2 0 Alpha-lytic protease prodomain HTH_19 PF12844.2 KEY74870.1 - 0.069 13.2 0.0 0.2 11.7 0.0 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain DEAD PF00270.24 KEY74872.1 - 0.013 14.9 0.0 0.014 14.8 0.0 1.0 1 0 0 1 1 1 0 DEAD/DEAH box helicase DDE_Tnp_1_7 PF13843.1 KEY74873.1 - 8.7e-10 38.1 0.0 1e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1_7 PF13843.1 KEY74875.1 - 0.054 12.5 0.0 0.069 12.1 0.0 1.1 1 0 0 1 1 1 0 Transposase IS4 F-box-like PF12937.2 KEY74876.1 - 0.0076 15.9 0.4 0.049 13.3 0.3 2.3 2 0 0 2 2 2 1 F-box-like Retrotrans_gag PF03732.12 KEY74877.1 - 0.0041 17.1 0.1 0.013 15.4 0.1 1.9 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_2 PF13696.1 KEY74877.1 - 0.08 12.4 0.7 0.19 11.2 0.5 1.7 1 0 0 1 1 1 0 Zinc knuckle UBN2_3 PF14244.1 KEY74877.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 KEY74877.1 - 0.2 11.6 1.9 0.36 10.8 1.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_S14 PF00253.16 KEY74877.1 - 1.1 8.6 4.7 2.6 7.4 3.3 1.7 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e CTP_transf_2 PF01467.21 KEY74878.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Cytidylyltransferase Ank_2 PF12796.2 KEY74879.1 - 3e-197 639.6 89.1 5.1e-19 68.4 0.7 9.5 1 1 13 15 15 15 15 Ankyrin repeats (3 copies) Ank PF00023.25 KEY74879.1 - 2.7e-101 326.6 63.6 5.1e-07 29.1 0.1 19.7 19 0 0 19 19 19 18 Ankyrin repeat Ank_4 PF13637.1 KEY74879.1 - 4.7e-75 246.7 37.6 6.2e-08 32.9 0.1 16.5 3 3 14 17 17 17 16 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY74879.1 - 1.2e-58 193.7 41.5 7.6e-08 32.3 0.5 16.2 4 4 14 18 18 18 18 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY74879.1 - 5.5e-51 165.4 44.9 5e-05 23.1 0.0 19.3 19 0 0 19 19 19 15 Ankyrin repeat NACHT PF05729.7 KEY74879.1 - 3e-11 43.2 0.1 5.8e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 KEY74879.1 - 2.7e-09 36.3 2.2 1e-08 34.4 0.9 2.4 2 1 0 2 2 2 1 Phosphorylase superfamily SopE_GEF PF07487.8 KEY74879.1 - 6.7e-09 35.9 12.7 1.4 8.8 0.0 8.2 1 1 7 9 9 9 3 SopE GEF domain AAA_16 PF13191.1 KEY74879.1 - 2.2e-05 24.5 0.0 7.6e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Mic1 PF07035.7 KEY74879.1 - 0.00076 18.8 5.8 1e+02 2.1 0.0 8.7 8 2 1 10 10 10 0 Colon cancer-associated protein Mic1-like NB-ARC PF00931.17 KEY74879.1 - 0.043 12.6 0.0 0.088 11.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.1 KEY74879.1 - 0.047 13.8 0.1 0.32 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Gas_vesicle PF00741.13 KEY74879.1 - 0.18 11.6 30.3 1e+02 2.9 0.0 12.2 14 0 0 14 14 14 0 Gas vesicle protein CDC45 PF02724.9 KEY74880.1 - 0.026 12.5 0.0 0.029 12.3 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 KEY74880.1 - 0.61 9.2 7.5 0.77 8.9 5.2 1.2 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.8 KEY74880.1 - 0.72 9.6 9.2 1 9.1 6.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 KEY74880.1 - 2.8 5.7 10.7 3.8 5.3 7.4 1.1 1 0 0 1 1 1 0 Nop14-like family DDE_Tnp_1_7 PF13843.1 KEY74881.1 - 1.8e-36 125.9 0.0 3.3e-36 125.0 0.0 1.5 1 1 0 1 1 1 1 Transposase IS4 Ank PF00023.25 KEY74882.1 - 1.5e-21 75.0 5.1 6e-06 25.8 0.1 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 KEY74882.1 - 2e-20 72.9 0.2 1.1e-08 35.2 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEY74882.1 - 1.1e-13 51.2 1.0 2.1e-06 28.0 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) NACHT PF05729.7 KEY74882.1 - 2.4e-13 50.0 0.1 4.9e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 NACHT domain Ank_3 PF13606.1 KEY74882.1 - 4.7e-12 44.8 0.5 0.012 15.7 0.0 5.6 6 0 0 6 6 4 2 Ankyrin repeat Ank_5 PF13857.1 KEY74882.1 - 9.7e-10 38.3 6.5 7.9e-05 22.7 0.5 4.7 2 1 3 5 5 5 4 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 KEY74882.1 - 2.2e-09 36.6 0.1 6.6e-09 35.0 0.1 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.1 KEY74882.1 - 5.1e-06 26.6 0.1 1.9e-05 24.7 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 KEY74882.1 - 0.0022 16.9 0.0 0.0047 15.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KEY74882.1 - 0.035 14.2 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KEY74882.1 - 0.063 13.0 0.0 2.1 8.1 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain DUF1966 PF09260.6 KEY74882.1 - 0.12 12.4 0.1 16 5.6 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1966) RNA_helicase PF00910.17 KEY74882.1 - 0.17 12.1 0.0 0.45 10.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Fungal_trans_2 PF11951.3 KEY74884.1 - 0.00022 19.9 0.5 0.00035 19.2 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cupin_2 PF07883.6 KEY74885.1 - 1.4e-07 30.9 0.0 2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 KEY74885.1 - 0.013 14.8 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) NmrA PF05368.8 KEY74886.1 - 1.2e-21 77.0 0.0 1.7e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY74886.1 - 8.9e-17 61.6 0.1 1.7e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEY74886.1 - 9.9e-06 25.1 0.3 0.001 18.5 0.1 2.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEY74886.1 - 9e-05 21.3 0.0 0.00016 20.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KEY74886.1 - 0.00043 19.2 0.0 0.0008 18.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein TrkA_N PF02254.13 KEY74886.1 - 0.0034 17.3 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Polysacc_synt_2 PF02719.10 KEY74886.1 - 0.011 14.6 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KEY74886.1 - 0.035 13.0 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Semialdhyde_dh PF01118.19 KEY74886.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KEY74886.1 - 0.13 12.6 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KEY74886.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DapB_N PF01113.15 KEY74886.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 KEY74887.1 - 3.9e-45 153.7 0.2 8.1e-45 152.6 0.1 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KEY74887.1 - 1.6e-38 132.2 0.4 1.6e-38 132.2 0.3 2.6 3 0 0 3 3 3 1 short chain dehydrogenase PP-binding PF00550.20 KEY74887.1 - 2.2e-09 37.4 0.0 7.8e-09 35.6 0.0 2.0 3 0 0 3 3 3 1 Phosphopantetheine attachment site ketoacyl-synt PF00109.21 KEY74888.1 - 2.3e-81 273.0 0.3 4.7e-81 272.0 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEY74888.1 - 1.6e-78 264.2 0.3 3.4e-78 263.1 0.2 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KEY74888.1 - 6.4e-39 132.4 3.2 1.8e-38 131.0 2.2 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 KEY74888.1 - 7.6e-12 44.9 0.0 9.8e-11 41.3 0.0 2.2 2 0 0 2 2 2 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 KEY74888.1 - 1.7e-05 23.9 0.0 4.5e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain UbiA PF01040.13 KEY74889.1 - 1.8e-31 109.2 25.3 2.3e-31 108.9 17.5 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family Stig1 PF04885.8 KEY74890.1 - 2.3e-74 248.0 157.9 1.7e-12 47.7 7.9 7.4 1 1 8 9 9 9 8 Stigma-specific protein, Stig1 Arm_2 PF04826.8 KEY74890.1 - 0.084 11.9 5.3 1.4e+02 1.3 0.0 6.5 2 2 6 8 8 8 0 Armadillo-like TPR_10 PF13374.1 KEY74892.1 - 1.5e-27 94.6 0.0 6.7e-12 44.9 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEY74892.1 - 7.9e-21 73.7 0.0 3e-11 43.0 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEY74892.1 - 1.7e-07 30.5 0.1 0.0082 15.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.9 KEY74892.1 - 0.00082 19.5 0.4 7 7.3 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEY74892.1 - 0.0017 18.1 0.0 1.8 8.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat NB-ARC PF00931.17 KEY74892.1 - 0.005 15.7 0.0 0.0078 15.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.1 KEY74892.1 - 0.01 15.5 0.0 6.9 6.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEY74892.1 - 0.018 14.6 0.0 0.99 9.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 KEY74892.1 - 0.092 12.9 0.0 0.82 10.0 0.0 2.5 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 KEY74892.1 - 0.092 12.4 0.0 0.73 9.5 0.0 2.3 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.1 KEY74892.1 - 1.5 9.6 4.7 29 5.6 0.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat AAA_22 PF13401.1 KEY74893.1 - 2.5e-06 27.6 0.0 1.3e-05 25.2 0.0 2.2 2 1 1 3 3 3 1 AAA domain NB-ARC PF00931.17 KEY74893.1 - 3.9e-05 22.6 0.0 5.9e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Abhydrolase_6 PF12697.2 KEY74893.1 - 0.00044 20.1 3.5 0.019 14.8 0.2 2.4 1 1 0 2 2 2 2 Alpha/beta hydrolase family AAA_16 PF13191.1 KEY74893.1 - 0.0015 18.5 0.4 0.02 14.8 0.4 2.5 2 1 0 2 2 2 1 AAA ATPase domain DUF676 PF05057.9 KEY74893.1 - 0.007 15.6 0.0 0.018 14.3 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Zeta_toxin PF06414.7 KEY74893.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.1 KEY74893.1 - 0.023 14.2 0.1 0.041 13.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KEY74893.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Abhydrolase_5 PF12695.2 KEY74893.1 - 0.1 12.3 0.4 0.5 10.1 0.2 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family PRA1 PF03208.14 KEY74894.1 - 4.7 6.5 6.5 1.5 8.1 0.2 2.2 2 0 0 2 2 2 0 PRA1 family protein WD40 PF00400.27 KEY74895.1 - 2.5e-107 347.3 57.1 1e-14 53.7 1.0 9.8 9 1 0 9 9 9 8 WD domain, G-beta repeat NACHT PF05729.7 KEY74895.1 - 1.2e-17 64.0 0.2 6.8e-17 61.6 0.0 2.4 4 0 0 4 4 4 1 NACHT domain Cytochrom_D1 PF02239.11 KEY74895.1 - 0.00049 18.5 6.0 0.2 9.9 0.0 4.0 2 2 2 4 4 4 2 Cytochrome D1 heme domain AAA_16 PF13191.1 KEY74895.1 - 0.01 15.8 0.0 0.11 12.5 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_11 PF13086.1 KEY74895.1 - 0.02 14.4 1.3 2.4 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KEY74895.1 - 0.024 14.7 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KEY74895.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Glyco_hydro_12 PF01670.11 KEY74897.1 - 3.7e-41 140.4 0.2 6e-41 139.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Glyco_hydro_43 PF04616.9 KEY74898.1 - 1.5e-30 106.2 4.7 6.8e-24 84.4 0.5 2.6 2 1 1 3 3 3 2 Glycosyl hydrolases family 43 TPR_12 PF13424.1 KEY74899.1 - 8.3e-63 208.3 0.7 1.4e-17 63.3 0.0 5.0 1 1 5 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 KEY74899.1 - 1.5e-58 193.1 0.0 5.2e-12 45.2 0.0 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 KEY74899.1 - 1.8e-13 49.5 2.2 0.022 14.9 0.0 5.7 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEY74899.1 - 2e-13 49.0 3.1 0.015 15.0 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.9 KEY74899.1 - 7.9e-12 44.4 3.4 0.019 15.3 0.0 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEY74899.1 - 1.5e-09 37.3 0.0 0.00073 19.1 0.0 3.7 3 1 1 4 4 4 3 TPR repeat TPR_14 PF13428.1 KEY74899.1 - 7.9e-08 32.2 3.7 2.6 8.9 0.0 6.4 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEY74899.1 - 1.1e-07 31.1 0.0 0.7 9.5 0.0 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEY74899.1 - 1.1e-07 32.2 0.2 0.13 12.9 0.0 5.1 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEY74899.1 - 2.1e-07 30.3 0.1 1.3 9.0 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEY74899.1 - 3.7e-07 29.4 0.0 1.9 8.4 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEY74899.1 - 2.5e-06 27.7 2.1 0.41 11.0 0.0 4.7 3 1 3 6 6 5 2 Tetratricopeptide repeat PPR_3 PF13812.1 KEY74899.1 - 0.00095 19.2 0.1 14 6.3 0.0 3.9 3 0 0 3 3 3 0 Pentatricopeptide repeat domain TPR_3 PF07720.7 KEY74899.1 - 0.0014 18.4 0.0 17 5.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_5 PF12688.2 KEY74899.1 - 0.0022 18.0 0.5 1.9 8.5 0.0 2.8 1 1 1 3 3 3 2 Tetratrico peptide repeat PPR PF01535.15 KEY74899.1 - 0.016 15.1 0.0 54 4.0 0.0 4.1 4 0 0 4 4 4 0 PPR repeat DUF2014 PF09427.5 KEY74899.1 - 0.029 13.5 3.1 4.9 6.2 0.0 3.4 1 1 3 4 4 4 0 Domain of unknown function (DUF2014) TPR_6 PF13174.1 KEY74899.1 - 0.14 12.6 8.0 42 4.8 0.0 5.1 6 1 0 6 6 5 0 Tetratricopeptide repeat F-box-like PF12937.2 KEY74900.1 - 0.00011 21.7 1.7 0.00054 19.6 0.2 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KEY74900.1 - 0.034 13.7 5.4 0.03 13.9 1.7 2.6 2 1 0 2 2 2 0 F-box domain adh_short PF00106.20 KEY74902.1 - 6.6e-19 68.4 0.1 9.5e-19 67.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY74902.1 - 1e-11 44.8 0.1 1.6e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY74902.1 - 1.8e-05 24.3 0.0 2.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KEY74902.1 - 0.0052 15.7 0.0 0.0083 15.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KEY74902.1 - 0.06 13.4 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 KEY74902.1 - 0.079 11.6 0.0 0.3 9.7 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KEY74902.1 - 0.11 12.5 0.1 0.21 11.5 0.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding DUF3940 PF13076.1 KEY74902.1 - 0.12 11.9 1.8 0.23 11.0 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3940) Ank_5 PF13857.1 KEY74903.1 - 4.1e-05 23.6 0.2 7.7e-05 22.8 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEY74903.1 - 0.00013 22.2 0.0 0.00024 21.3 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEY74903.1 - 0.00025 21.4 0.1 0.00052 20.4 0.0 1.7 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 KEY74903.1 - 0.0021 17.7 1.0 0.0048 16.6 0.0 2.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 KEY74903.1 - 0.023 14.8 0.0 0.082 13.1 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat Rad21_Rec8_N PF04825.8 KEY74905.1 - 1.1e-32 112.2 0.0 1.9e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KEY74905.1 - 1.6e-07 30.3 0.0 3.9e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein NRPS PF08415.5 KEY74905.1 - 0.051 13.3 0.1 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 Nonribosomal peptide synthase ScpA_ScpB PF02616.9 KEY74905.1 - 0.093 12.2 0.1 1.5 8.3 0.0 2.5 3 0 0 3 3 3 0 ScpA/B protein O-antigen_lig PF13425.1 KEY74908.1 - 0.004 17.1 0.0 0.0051 16.7 0.0 1.1 1 0 0 1 1 1 1 O-antigen ligase like membrane protein Peptidase_S8 PF00082.17 KEY74910.1 - 5.2e-23 81.6 7.8 5e-15 55.4 2.4 2.1 1 1 1 2 2 2 2 Subtilase family Inhibitor_I9 PF05922.11 KEY74910.1 - 6e-06 26.7 0.0 1.3e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 TPR_12 PF13424.1 KEY74911.1 - 1.3e-11 44.2 0.1 8.2e-07 28.8 0.0 2.7 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 KEY74911.1 - 2.7e-09 36.6 0.1 1.4e-05 24.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEY74911.1 - 9.5e-08 32.2 0.4 0.027 14.8 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEY74911.1 - 6.8e-07 29.3 0.1 0.26 12.0 0.0 3.8 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 KEY74911.1 - 0.00017 21.7 0.1 2.6 8.7 0.0 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEY74911.1 - 0.00041 20.0 3.0 0.49 10.4 0.2 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEY74911.1 - 0.0028 17.3 0.1 1.4 8.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEY74911.1 - 0.005 17.2 1.0 0.56 10.7 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEY74911.1 - 0.0065 16.1 0.8 25 4.9 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEY74911.1 - 0.027 15.1 0.3 13 6.6 0.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEY74911.1 - 0.28 10.8 1.8 2.9 7.6 0.2 3.0 3 1 1 4 4 4 0 Tetratricopeptide repeat XkdW PF09636.5 KEY74912.1 - 0.021 14.6 1.6 0.12 12.2 0.4 2.2 1 1 0 1 1 1 0 XkdW protein Reo_sigmaC PF04582.7 KEY74912.1 - 0.032 13.4 0.6 0.041 13.0 0.4 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Spc7 PF08317.6 KEY74912.1 - 0.069 11.7 8.5 0.099 11.2 5.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Pga1 PF10333.4 KEY74912.1 - 0.078 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 GPI-Mannosyltransferase II co-activator Surfac_D-trimer PF09006.6 KEY74912.1 - 0.093 12.4 0.3 0.2 11.4 0.2 1.6 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation AAA_13 PF13166.1 KEY74912.1 - 0.12 10.8 8.0 0.14 10.5 5.6 1.1 1 0 0 1 1 1 0 AAA domain HWE_HK PF07536.9 KEY74912.1 - 0.28 11.6 4.5 2.3 8.7 2.1 2.5 2 1 0 2 2 2 0 HWE histidine kinase Atg14 PF10186.4 KEY74912.1 - 0.7 8.7 11.0 1.2 7.9 7.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SYCE1 PF15233.1 KEY74912.1 - 0.79 9.6 12.8 0.17 11.8 3.0 2.3 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 DUF4140 PF13600.1 KEY74912.1 - 1.1 9.7 15.0 0.71 10.3 4.2 3.1 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) ADIP PF11559.3 KEY74912.1 - 2.5 7.9 13.1 3.9 7.3 9.1 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 KEY74912.1 - 7.3 6.1 13.1 15 5.0 9.0 1.5 1 1 0 1 1 1 0 IncA protein Ank_2 PF12796.2 KEY74913.1 - 1.6e-27 95.6 0.4 8.8e-09 35.5 0.0 5.1 3 3 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KEY74913.1 - 4.1e-23 79.9 1.1 1.8e-06 27.4 0.0 6.8 6 1 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 KEY74913.1 - 1.2e-19 68.4 5.1 1.2e-05 25.0 0.0 7.6 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.1 KEY74913.1 - 3.4e-18 65.6 5.9 2.7e-07 30.8 0.0 7.0 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY74913.1 - 4.4e-15 55.3 4.7 0.00018 21.6 0.0 6.5 5 2 1 6 6 6 3 Ankyrin repeats (many copies) Pkinase PF00069.20 KEY74914.1 - 7.8e-18 64.5 0.0 1.9e-17 63.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY74914.1 - 1.2e-12 47.5 0.0 2.3e-12 46.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Cyclase PF04199.8 KEY74914.1 - 0.038 13.6 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative cyclase APH PF01636.18 KEY74914.1 - 0.054 13.2 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KEY74914.1 - 0.063 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KEY74914.1 - 0.084 11.6 0.1 0.82 8.3 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase HeLo PF14479.1 KEY74915.1 - 6.3e-17 62.0 0.0 1.5e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Prion-inhibition and propagation Abhydrolase_2 PF02230.11 KEY74916.1 - 1.5e-28 99.7 0.0 1.2e-19 70.6 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KEY74916.1 - 2.1e-05 24.5 0.2 0.0015 18.4 0.1 2.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEY74916.1 - 2.9e-05 23.8 0.0 5.3e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEY74916.1 - 0.0014 17.8 0.1 0.0089 15.2 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.8 KEY74916.1 - 0.0016 17.9 0.0 0.0026 17.2 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PE-PPE PF08237.6 KEY74916.1 - 0.02 14.3 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain LIP PF03583.9 KEY74916.1 - 0.069 12.3 0.0 0.27 10.4 0.0 1.8 2 0 0 2 2 2 0 Secretory lipase FAD_binding_3 PF01494.14 KEY74917.1 - 7.9e-08 31.7 1.2 0.051 12.6 0.3 3.2 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 KEY74917.1 - 0.0035 17.3 0.0 0.0077 16.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KEY74917.1 - 0.036 14.4 0.0 0.11 12.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEY74917.1 - 0.061 12.2 0.1 0.1 11.4 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KEY74917.1 - 0.078 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 KEY74917.1 - 0.096 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Fungal_trans_2 PF11951.3 KEY74918.1 - 0.0014 17.2 0.0 0.0023 16.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA PF00004.24 KEY74919.1 - 9.6e-20 71.1 0.0 2.1e-19 69.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) adh_short PF00106.20 KEY74919.1 - 4.8e-12 46.1 0.7 9.1e-12 45.2 0.5 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY74919.1 - 2e-07 30.8 1.0 4.9e-07 29.5 0.7 1.6 1 0 0 1 1 1 1 KR domain AAA_16 PF13191.1 KEY74919.1 - 0.0012 18.8 0.0 0.0061 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KEY74919.1 - 0.0036 17.5 0.7 0.048 13.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEY74919.1 - 0.0056 16.8 0.0 0.021 14.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEY74919.1 - 0.0057 17.4 0.1 0.023 15.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEY74919.1 - 0.0076 15.9 0.0 0.043 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KEY74919.1 - 0.042 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KEY74919.1 - 0.16 11.5 0.0 0.51 9.9 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 KEY74919.1 - 0.24 10.0 0.0 0.41 9.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Arylsulfotran_2 PF14269.1 KEY74922.1 - 1.2e-57 195.4 0.2 1.5e-57 195.0 0.1 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KEY74922.1 - 6.8e-13 47.9 0.1 3.5e-12 45.5 0.1 1.9 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Sulfatase PF00884.18 KEY74923.1 - 4.9e-58 196.7 0.3 6.3e-58 196.3 0.2 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KEY74923.1 - 4.9e-06 26.1 4.4 2.5e-05 23.7 3.1 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KEY74923.1 - 0.073 11.4 0.0 0.13 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Fungal_trans PF04082.13 KEY74924.1 - 5e-13 48.5 1.1 6.2e-13 48.2 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAD-oxidase_C PF02913.14 KEY74925.1 - 1.3e-62 211.3 0.1 2.1e-62 210.6 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KEY74925.1 - 1.6e-39 134.5 0.0 3.1e-39 133.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Aminotran_1_2 PF00155.16 KEY74926.1 - 1.6e-62 211.5 0.0 1.8e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KEY74926.1 - 0.0017 16.7 0.0 0.0046 15.2 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 KEY74926.1 - 0.025 13.7 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase MFS_1 PF07690.11 KEY74927.1 - 8.5e-44 149.6 31.9 1.8e-43 148.6 22.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY74927.1 - 2e-11 43.1 2.3 2e-11 43.1 1.6 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KEY74927.1 - 3.3e-07 28.9 5.5 5.9e-07 28.0 3.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KEY74927.1 - 8.1e-06 24.2 0.8 8.1e-06 24.2 0.6 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_1 PF07690.11 KEY74928.1 - 2.7e-36 125.0 22.4 2.7e-36 125.0 15.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Hepatitis_core PF00906.15 KEY74929.1 - 0.038 13.6 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 Hepatitis core antigen Glyco_hydro_2_C PF02836.12 KEY74930.1 - 1.6e-29 102.7 0.0 2.3e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 KEY74930.1 - 7.6e-29 100.4 0.1 2.7e-28 98.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KEY74930.1 - 1.8e-12 47.6 0.0 4.5e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Big_1 PF02369.11 KEY74930.1 - 0.0085 15.9 0.5 0.03 14.2 0.2 2.0 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 1) DUF4177 PF13783.1 KEY74932.1 - 0.017 14.7 1.0 0.17 11.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4177) p450 PF00067.17 KEY74933.1 - 0.00027 19.6 0.0 0.00037 19.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.1 KEY74935.1 - 1.9e-24 86.7 0.3 2.2e-24 86.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEY74935.1 - 1.9e-23 83.2 2.7 1.9e-23 83.2 1.9 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY74935.1 - 9.1e-09 35.2 0.6 1.5e-08 34.5 0.4 1.2 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.10 KEY74935.1 - 7.9e-05 22.3 0.3 0.00015 21.4 0.2 1.5 1 0 0 1 1 1 1 YjeF-related protein N-terminus Epimerase PF01370.16 KEY74935.1 - 0.015 14.7 1.2 0.055 12.8 0.8 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KEY74935.1 - 0.045 13.4 0.4 0.073 12.7 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Tocopherol_cycl PF14249.1 KEY74936.1 - 0.068 11.8 0.1 0.083 11.5 0.1 1.1 1 0 0 1 1 1 0 Tocopherol cyclase NUFIP1 PF10453.4 KEY74936.1 - 0.17 11.4 1.2 0.4 10.2 0.1 2.0 2 1 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) PfkB PF00294.19 KEY74937.1 - 1.1e-14 54.2 0.0 1.6e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Transp_cyt_pur PF02133.10 KEY74938.1 - 2e-88 296.8 46.5 2.5e-88 296.5 32.2 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3260 PF11658.3 KEY74938.1 - 0.09 10.9 0.2 0.16 10.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF221 PF02714.10 KEY74939.1 - 8e-91 304.2 10.9 1.9e-90 303.0 7.5 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KEY74939.1 - 3e-39 134.1 3.8 8.6e-39 132.6 2.6 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KEY74939.1 - 9.5e-22 76.6 0.1 2.1e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KEY74939.1 - 1.2e-11 44.9 0.1 2.5e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Glyco_hydro_61 PF03443.9 KEY74940.1 - 1.5e-44 152.4 0.0 2e-44 152.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KEY74940.1 - 5.7e-11 41.8 14.8 1.6e-10 40.4 10.2 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KEY74940.1 - 0.34 10.9 2.5 0.88 9.6 1.7 1.7 1 0 0 1 1 1 0 Toxin 7 Sporozoite_P67 PF05642.6 KEY74940.1 - 1.7 6.4 4.6 2.2 6.0 3.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hydro_31 PF01055.21 KEY74941.1 - 2.9e-165 550.3 3.1 3.7e-165 550.0 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KEY74941.1 - 2e-09 37.1 1.1 5.9e-09 35.6 0.7 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like MFS_1 PF07690.11 KEY74942.1 - 2.2e-36 125.3 46.7 1.4e-29 102.8 26.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_92 PF07971.7 KEY74943.1 - 1.6e-152 508.6 0.0 2.2e-152 508.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Acetyltransf_1 PF00583.19 KEY74943.1 - 0.013 15.4 0.0 0.041 13.9 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Fungal_trans PF04082.13 KEY74944.1 - 7.2e-10 38.1 0.0 1.5e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY74944.1 - 2.5e-07 30.4 10.3 2.5e-07 30.4 7.2 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nup_retrotrp_bd PF10599.4 KEY74944.1 - 1.8 9.2 7.5 1.3 9.6 3.9 1.7 1 1 0 1 1 1 0 Retro-transposon transporting motif Polyketide_cyc2 PF10604.4 KEY74945.1 - 3.1e-08 33.9 2.3 6.9e-08 32.7 1.6 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF4165 PF13752.1 KEY74945.1 - 0.082 12.6 0.3 0.1 12.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4165) DAD PF02109.11 KEY74945.1 - 0.1 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 DAD family Polyketide_cyc PF03364.15 KEY74945.1 - 0.16 11.9 1.2 0.37 10.8 0.8 1.8 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport G_glu_transpept PF01019.16 KEY74947.1 - 1.6e-157 525.1 0.0 1.8e-157 524.9 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Gln-synt_C PF00120.19 KEY74948.1 - 2.7e-35 121.7 0.0 3.4e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Tobravirus_2B PF05271.6 KEY74948.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Tobravirus 2B protein Glyco_hydro_6 PF01341.12 KEY74950.1 - 0.00062 19.2 0.0 0.00066 19.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Fungal_trans PF04082.13 KEY74951.1 - 5.6e-21 74.5 0.1 1.9e-20 72.8 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY74951.1 - 1.5e-05 24.7 7.9 2.6e-05 24.0 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 KEY74952.1 - 5.5e-91 305.6 0.1 9.4e-91 304.8 0.0 1.3 1 0 0 1 1 1 1 Amidase AHS2 PF02626.10 KEY74952.1 - 1.9e-82 276.6 0.0 3.2e-82 275.8 0.0 1.4 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 KEY74952.1 - 5.9e-66 221.7 0.1 1.1e-65 220.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AHS1 PF02682.11 KEY74952.1 - 2.3e-34 118.6 0.0 4.4e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 CPSase_L_chain PF00289.17 KEY74952.1 - 5.9e-33 113.2 0.1 1.3e-32 112.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KEY74952.1 - 3.6e-31 107.3 0.0 2.5e-30 104.6 0.0 2.4 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 KEY74952.1 - 6.4e-14 51.3 0.1 1.7e-13 49.9 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KEY74952.1 - 1.4e-10 41.2 0.0 3.6e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KEY74952.1 - 1.5e-09 37.5 0.0 2.7e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 KEY74952.1 - 5.8e-08 32.2 0.0 0.0072 15.9 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATPgrasp_Ter PF15632.1 KEY74952.1 - 6.7e-07 28.3 0.0 1.4e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.1 KEY74952.1 - 2.1e-05 23.8 0.3 4.5e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KEY74952.1 - 6.2e-05 22.5 0.0 0.00014 21.4 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KEY74952.1 - 0.023 14.5 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain HlyD PF00529.15 KEY74952.1 - 0.12 11.6 0.0 2.2 7.5 0.0 2.5 1 1 1 2 2 2 0 HlyD family secretion protein HlyD_2 PF12700.2 KEY74952.1 - 0.16 11.0 0.0 0.38 9.8 0.0 1.6 1 0 0 1 1 1 0 HlyD family secretion protein Ctr PF04145.10 KEY74954.1 - 3.5e-08 33.5 0.3 3.9e-08 33.4 0.2 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Prokineticin PF06607.6 KEY74955.1 - 0.19 11.8 2.9 0.25 11.4 2.0 1.3 1 1 0 1 1 1 0 Prokineticin SRR1 PF07985.7 KEY74956.1 - 7.8e-05 22.5 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 SRR1 Plasmodium_Vir PF05795.6 KEY74957.1 - 0.015 14.5 0.1 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1174 PF06671.6 KEY74957.1 - 0.017 14.7 4.2 0.017 14.7 2.9 2.5 2 0 0 2 2 2 0 Repeat of unknown function (DUF1174) DUF1517 PF07466.6 KEY74957.1 - 0.17 10.8 1.5 0.23 10.3 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Macoilin PF09726.4 KEY74957.1 - 2.7 6.1 5.0 3.6 5.7 3.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Alpha_GJ PF03229.8 KEY74957.1 - 3.8 7.8 7.5 0.18 12.1 1.3 1.7 2 0 0 2 2 2 0 Alphavirus glycoprotein J Trs65 PF12735.2 KEY74957.1 - 8.4 5.5 9.9 12 5.0 6.9 1.1 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 Abhydrolase_5 PF12695.2 KEY74958.1 - 7.9e-07 28.9 0.1 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KEY74958.1 - 3.6e-05 23.2 0.0 8.1e-05 22.1 0.0 1.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.15 KEY74958.1 - 6.7e-05 22.4 0.1 8.7e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 KEY74958.1 - 0.00031 20.0 0.7 0.001 18.3 0.4 1.8 1 1 1 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 KEY74958.1 - 0.0024 17.1 0.0 0.0037 16.5 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase PHD PF00628.24 KEY74960.1 - 6e-13 48.2 21.8 3.9e-08 32.8 8.6 3.6 4 1 0 4 4 4 2 PHD-finger zf-HC5HC2H PF13771.1 KEY74960.1 - 0.027 14.6 0.3 0.027 14.6 0.2 3.3 3 0 0 3 3 3 0 PHD-like zinc-binding domain Beta_helix PF13229.1 KEY74961.1 - 4.8e-10 39.4 20.8 1.7e-08 34.3 3.0 2.5 1 1 1 2 2 2 2 Right handed beta helix region tRNA-synt_2c PF01411.14 KEY74961.1 - 1.3e-07 30.2 0.1 2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KEY74961.1 - 1.1e-05 25.1 0.5 1.9e-05 24.4 0.3 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Chondroitinas_B PF14592.1 KEY74961.1 - 0.00018 20.4 0.2 0.00039 19.3 0.0 1.5 2 0 0 2 2 2 1 Chondroitinase B Glyco_hydro_67M PF07488.7 KEY74962.1 - 2.8e-138 460.2 0.0 3.7e-138 459.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 KEY74962.1 - 1.3e-83 279.8 0.2 2.1e-83 279.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 KEY74962.1 - 4.5e-18 65.4 0.0 1.3e-15 57.5 0.0 2.9 2 1 0 2 2 2 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.10 KEY74962.1 - 0.1 13.1 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_11 PF00457.12 KEY74963.1 - 5.7e-70 234.3 20.6 7.3e-70 234.0 14.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Glyco_hydro_71 PF03659.9 KEY74964.1 - 0.1 11.0 0.0 0.11 10.8 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 71 LVIVD PF08309.6 KEY74965.1 - 6.3e-05 21.8 3.9 0.041 12.8 0.8 3.9 3 1 1 4 4 4 2 LVIVD repeat NmrA PF05368.8 KEY74966.1 - 4.9e-27 94.6 0.0 1.1e-26 93.5 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 KEY74966.1 - 7.2e-17 61.9 0.0 1e-16 61.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding HTH_psq PF05225.11 KEY74966.1 - 0.024 14.1 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Fungal_trans_2 PF11951.3 KEY74967.1 - 7e-13 47.9 4.3 3e-09 35.9 0.3 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain LNS2 PF08235.8 KEY74967.1 - 0.0048 16.4 0.0 0.0081 15.7 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Noelin-1 PF12308.3 KEY74967.1 - 0.076 12.8 0.0 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Neurogenesis glycoprotein adh_short PF00106.20 KEY74968.1 - 4.4e-31 108.0 1.2 7.3e-31 107.3 0.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY74968.1 - 4.5e-16 59.0 0.7 8.7e-16 58.1 0.4 1.4 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KEY74968.1 - 2.3e-07 30.8 0.0 2.9e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEY74968.1 - 6.5e-06 25.7 0.2 1.6e-05 24.4 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KEY74968.1 - 1.9e-05 23.9 0.0 2.7e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KEY74968.1 - 0.0056 16.7 0.3 0.0092 15.9 0.2 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KEY74968.1 - 0.019 14.2 0.2 0.31 10.2 0.1 2.5 2 1 1 3 3 3 0 NmrA-like family Trypsin PF00089.21 KEY74969.1 - 6.3e-68 228.6 7.4 7.2e-68 228.4 5.1 1.0 1 0 0 1 1 1 1 Trypsin Toxin_4 PF00706.12 KEY74969.1 - 0.017 15.3 0.1 0.044 14.0 0.1 1.8 1 0 0 1 1 1 0 Anenome neurotoxin PgaD PF13994.1 KEY74971.1 - 0.92 8.9 8.0 0.096 12.1 0.7 2.6 3 0 0 3 3 3 0 PgaD-like protein adh_short_C2 PF13561.1 KEY74972.1 - 1.2e-30 107.1 0.0 1.5e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEY74972.1 - 2.8e-26 92.4 0.1 3.9e-26 91.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY74972.1 - 1.9e-13 50.5 0.0 4.1e-13 49.3 0.0 1.5 1 1 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 KEY74972.1 - 0.11 11.6 0.0 0.23 10.6 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 KEY74973.1 - 2.8e-22 79.7 0.0 1.1e-19 71.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEY74973.1 - 3.8e-13 48.4 0.0 6.2e-10 37.8 0.0 3.0 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KEY74973.1 - 3.8e-12 45.7 0.0 3.4e-10 39.3 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KEY74973.1 - 1.2e-07 31.7 0.0 2.1e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY74973.1 - 3.1e-05 23.8 0.0 9.4e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KEY74973.1 - 0.01 14.9 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KEY74973.1 - 0.014 15.7 0.4 4.9 7.6 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 KEY74974.1 - 2.6e-34 118.4 22.7 1.6e-33 115.8 16.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2649 PF10854.3 KEY74974.1 - 0.13 12.3 0.3 0.13 12.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2649) DUF1049 PF06305.6 KEY74974.1 - 1.2 8.6 3.8 3.7 7.1 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) TPP_enzyme_N PF02776.13 KEY74975.1 - 2.7e-39 134.4 0.0 4.2e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KEY74975.1 - 5.6e-20 71.5 0.0 2.1e-19 69.6 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KEY74975.1 - 1.7e-13 50.4 0.0 3.1e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Aldedh PF00171.17 KEY74976.1 - 5.5e-131 437.0 0.0 6.9e-131 436.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KEY74976.1 - 0.0011 18.3 0.0 0.0025 17.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) UbiD PF01977.11 KEY74977.1 - 6.5e-116 387.1 0.0 7.5e-116 386.9 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Fungal_trans PF04082.13 KEY74978.1 - 3.3e-08 32.7 0.0 6.6e-08 31.7 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KEY74979.1 - 6.7e-36 123.7 44.6 6.7e-36 123.7 30.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 KEY74979.1 - 0.32 8.9 7.7 2.1 6.2 1.8 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 KEY74981.1 - 6.4e-21 74.4 63.4 2.2e-18 66.1 32.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Bacteriocin_IIc PF10439.4 KEY74982.1 - 0.012 15.6 12.1 0.012 15.6 8.4 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Atrophin-1 PF03154.10 KEY74982.1 - 0.023 12.8 0.2 0.032 12.3 0.1 1.2 1 0 0 1 1 1 0 Atrophin-1 family Gly-zipper_OmpA PF13436.1 KEY74982.1 - 0.13 11.9 19.1 0.12 12.0 10.4 2.6 2 1 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DUF4407 PF14362.1 KEY74982.1 - 1 8.2 5.5 0.083 11.8 0.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Fungal_trans PF04082.13 KEY74983.1 - 5e-17 61.6 0.3 2e-16 59.6 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY74983.1 - 2.6e-05 24.0 13.0 2.6e-05 24.0 9.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PLDc_N PF13396.1 KEY74984.1 - 5e-08 32.4 8.3 5e-08 32.4 5.7 2.0 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal DUF3951 PF13131.1 KEY74984.1 - 0.29 10.9 0.0 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) DUF4131 PF13567.1 KEY74984.1 - 0.31 10.4 2.9 0.46 9.8 2.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4064 PF13273.1 KEY74984.1 - 2.4 8.2 5.9 3.7 7.7 4.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF2069 PF09842.4 KEY74984.1 - 4.4 7.3 6.3 0.82 9.6 1.8 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2069) AAA_16 PF13191.1 KEY74985.1 - 4.1e-11 43.1 0.0 3.8e-10 40.0 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEY74985.1 - 4.2e-05 23.6 0.4 0.00062 19.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain TPR_16 PF13432.1 KEY74985.1 - 0.00019 21.9 0.0 16 6.3 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat NACHT PF05729.7 KEY74985.1 - 0.0023 17.6 0.0 0.018 14.6 0.0 2.7 1 0 0 1 1 1 1 NACHT domain Glyco_hydro_35 PF01301.14 KEY74986.1 - 8.2e-85 284.9 0.4 1.1e-84 284.5 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 KEY74986.1 - 3.1e-50 169.0 0.7 5.8e-27 94.1 0.4 3.0 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 KEY74986.1 - 2.6e-47 160.5 1.1 4e-47 159.9 0.7 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 KEY74986.1 - 1.7e-19 68.9 0.0 4.1e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.10 KEY74986.1 - 0.00062 18.9 0.0 0.0026 16.9 0.0 1.9 1 1 0 1 1 1 1 Beta-galactosidase Sugar_tr PF00083.19 KEY74987.1 - 6.9e-70 235.8 27.5 7.9e-70 235.6 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY74987.1 - 4.1e-09 35.6 48.4 5.7e-09 35.1 26.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEY74987.1 - 0.00029 19.3 8.3 0.00029 19.3 5.8 3.4 2 2 1 3 3 3 2 MFS/sugar transport protein UNC-93 PF05978.11 KEY74987.1 - 0.0047 16.4 4.0 0.0047 16.4 2.8 3.1 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 PGC7_Stella PF15549.1 KEY74988.1 - 0.24 11.3 3.8 0.54 10.2 2.6 1.5 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain Hrs_helical PF12210.3 KEY74988.1 - 0.63 10.3 6.7 5.6 7.2 0.0 3.4 2 1 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF3425 PF11905.3 KEY74989.1 - 6.4e-26 90.8 0.0 1.5e-25 89.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KEY74989.1 - 0.0017 18.2 11.7 0.0028 17.5 8.1 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 KEY74989.1 - 0.0069 16.6 7.1 0.012 15.8 4.9 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor HOOK PF05622.7 KEY74989.1 - 0.012 13.4 0.0 0.016 13.0 0.0 1.0 1 0 0 1 1 1 0 HOOK protein bZIP_2 PF07716.10 KEY74989.1 - 0.066 13.0 13.7 0.1 12.4 9.5 1.3 1 0 0 1 1 1 0 Basic region leucine zipper TSC22 PF01166.13 KEY74989.1 - 0.1 12.5 0.2 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Herpes_UL6 PF01763.11 KEY74989.1 - 0.21 9.7 0.0 0.26 9.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DivIC PF04977.10 KEY74989.1 - 0.62 9.5 3.8 0.53 9.8 0.6 2.0 1 1 1 2 2 2 0 Septum formation initiator DUF4140 PF13600.1 KEY74989.1 - 0.87 10.0 3.8 1.5 9.2 2.6 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Acetyltransf_7 PF13508.1 KEY74990.1 - 3e-06 27.3 0.2 8.4e-06 25.8 0.1 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEY74990.1 - 0.00012 22.0 0.4 0.00048 20.0 0.1 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KEY74990.1 - 0.00072 19.4 0.4 0.033 14.0 0.0 3.1 2 1 0 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEY74990.1 - 0.013 15.2 0.0 0.041 13.6 0.0 1.9 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 KEY74990.1 - 0.064 13.1 0.1 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase NIPSNAP PF07978.8 KEY74990.1 - 0.068 13.1 0.4 0.11 12.4 0.3 1.4 1 0 0 1 1 1 0 NIPSNAP Acetyltransf_10 PF13673.1 KEY74990.1 - 0.11 12.6 0.2 0.29 11.2 0.1 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4238 PF14022.1 KEY74991.1 - 9.8e-17 61.0 0.0 1.2e-16 60.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) Prim-Pol PF09250.6 KEY74991.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.5 2 0 0 2 2 2 0 Bifunctional DNA primase/polymerase, N-terminal Ank_2 PF12796.2 KEY74994.1 - 9.1e-91 298.3 32.5 9e-20 70.8 0.8 8.6 3 1 5 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.25 KEY74994.1 - 2.1e-78 254.4 48.0 9.9e-08 31.4 0.4 16.4 15 1 1 16 16 16 12 Ankyrin repeat Ank_4 PF13637.1 KEY74994.1 - 3.4e-60 199.4 12.5 9e-10 38.8 0.1 12.1 5 3 4 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY74994.1 - 1.6e-53 173.2 20.3 2.2e-05 24.2 0.0 14.9 16 0 0 16 16 16 10 Ankyrin repeat Ank_5 PF13857.1 KEY74994.1 - 1.5e-50 168.0 26.3 2e-08 34.2 0.0 10.1 5 3 4 10 10 10 10 Ankyrin repeats (many copies) NACHT PF05729.7 KEY74994.1 - 8.5e-14 51.5 0.0 2.9e-13 49.8 0.0 2.0 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KEY74994.1 - 2.3e-08 34.2 0.1 1.1e-07 32.0 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEY74994.1 - 2e-06 27.9 0.1 1.2e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 KEY74994.1 - 0.0079 15.3 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA PF00004.24 KEY74994.1 - 0.036 14.2 0.0 0.15 12.3 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 KEY74994.1 - 0.065 12.9 0.0 0.4 10.3 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Shigella_OspC PF06128.6 KEY74994.1 - 0.1 12.0 0.2 19 4.6 0.0 3.4 3 0 0 3 3 3 0 Shigella flexneri OspC protein RNA_helicase PF00910.17 KEY74994.1 - 0.25 11.5 0.0 0.71 10.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Coat_F PF07875.7 KEY74995.1 - 0.11 12.5 0.1 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Coat F domain Fungal_trans PF04082.13 KEY74996.1 - 1.9e-29 102.3 0.3 3.1e-29 101.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY74996.1 - 3.5e-08 33.2 10.8 7.8e-08 32.1 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AvrE PF11725.3 KEY74996.1 - 0.46 7.4 3.1 0.6 7.0 2.2 1.0 1 0 0 1 1 1 0 Pathogenicity factor Mannitol_dh_C PF08125.8 KEY74997.1 - 1.4e-72 243.8 0.0 1.9e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 KEY74997.1 - 2.7e-46 157.2 0.0 4.8e-46 156.4 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain Exotox-A_bind PF09101.5 KEY74997.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Exotoxin A binding Rieske PF00355.21 KEY74998.1 - 1e-13 50.6 0.0 2.1e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.14 KEY74998.1 - 0.0013 18.4 0.9 0.55 9.8 0.1 2.5 1 1 0 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) PilJ PF13675.1 KEY74998.1 - 0.069 13.4 0.9 0.12 12.6 0.6 1.3 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Sar8_2 PF03058.9 KEY74998.1 - 0.07 13.4 0.8 0.2 11.9 0.5 1.7 1 0 0 1 1 1 0 Sar8.2 family DUF3186 PF11382.3 KEY74998.1 - 0.2 10.7 2.0 0.28 10.2 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Ring_hydroxyl_A PF00848.14 KEY74999.1 - 1.5e-30 106.4 3.4 1.4e-29 103.3 2.3 2.0 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Toxin_51 PF15531.1 KEY74999.1 - 0.029 14.1 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative toxin 51 Zn_clus PF00172.13 KEY75000.1 - 1.2e-05 25.0 13.7 2.4e-05 24.1 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RCR PF12273.3 KEY75000.1 - 0.018 15.5 0.0 0.041 14.4 0.0 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Herpes_gE PF02480.11 KEY75000.1 - 0.038 12.2 0.0 0.059 11.6 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DAO PF01266.19 KEY75001.1 - 4.4e-45 154.1 0.1 5.3e-45 153.8 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY75001.1 - 5.5e-07 29.5 0.0 1.3e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KEY75001.1 - 1.9e-05 24.6 0.0 0.00046 20.1 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY75001.1 - 0.0035 17.7 0.0 0.016 15.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEY75001.1 - 0.0037 16.1 0.0 0.015 14.1 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KEY75001.1 - 0.013 15.6 0.0 0.035 14.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEY75001.1 - 0.039 13.7 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KEY75001.1 - 0.047 12.7 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 KEY75001.1 - 0.088 12.1 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 KEY75001.1 - 0.098 12.0 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 KEY75001.1 - 0.12 12.1 0.0 0.43 10.3 0.0 1.8 2 0 0 2 2 2 0 ThiF family 3HCDH_N PF02737.13 KEY75001.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_3 PF07859.8 KEY75002.1 - 2.3e-13 50.2 0.3 2.1e-12 47.0 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEY75002.1 - 2.8e-12 47.0 0.2 4.2e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEY75002.1 - 2e-10 40.2 0.0 9.8e-06 24.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEY75002.1 - 2.4e-10 40.3 0.0 5.8e-10 39.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 KEY75002.1 - 7.4e-08 31.5 0.0 1.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 KEY75002.1 - 1.1e-07 30.9 0.0 1.8e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme COesterase PF00135.23 KEY75002.1 - 1.3e-05 24.1 0.1 5.4e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Carboxylesterase family Esterase PF00756.15 KEY75002.1 - 7e-05 22.3 0.1 0.0005 19.5 0.0 2.0 2 0 0 2 2 2 1 Putative esterase Esterase_phd PF10503.4 KEY75002.1 - 0.0016 17.7 0.0 0.019 14.1 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase DUF2424 PF10340.4 KEY75002.1 - 0.022 13.4 0.0 0.031 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) DLH PF01738.13 KEY75002.1 - 0.076 12.2 0.0 0.31 10.2 0.0 2.0 2 1 0 2 2 2 0 Dienelactone hydrolase family Transferase PF02458.10 KEY75003.1 - 0.00035 19.1 0.0 0.00046 18.7 0.0 1.2 1 0 0 1 1 1 1 Transferase family DAO PF01266.19 KEY75004.1 - 3.6e-20 72.1 0.7 4.4e-20 71.9 0.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEY75004.1 - 0.0037 17.6 1.5 0.0081 16.5 1.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY75004.1 - 0.0059 16.6 0.0 0.0087 16.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF3886 PF13025.1 KEY75004.1 - 0.27 11.2 1.2 0.42 10.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) Aldo_ket_red PF00248.16 KEY75005.1 - 1.5e-57 194.5 0.0 2.2e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Adenine_deam_C PF13382.1 KEY75005.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Adenine deaminase C-terminal domain Cytomega_UL20A PF05984.7 KEY75006.1 - 0.0067 16.6 0.0 0.0067 16.6 0.0 2.4 2 1 1 3 3 3 1 Cytomegalovirus UL20A protein Epimerase PF01370.16 KEY75007.1 - 1.8e-62 210.8 0.0 2.2e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEY75007.1 - 1.7e-23 82.7 0.0 2.3e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KEY75007.1 - 3.9e-17 62.1 0.0 4e-16 58.7 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KEY75007.1 - 1.4e-15 56.9 0.0 2e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KEY75007.1 - 4.7e-14 51.9 0.0 8.2e-13 47.8 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KEY75007.1 - 1.9e-11 44.1 0.3 4.3e-11 43.0 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KEY75007.1 - 1.5e-09 38.0 0.1 4.5e-09 36.5 0.0 1.8 2 1 0 2 2 2 1 NADH(P)-binding KR PF08659.5 KEY75007.1 - 1.2e-06 28.2 0.0 1.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 KEY75007.1 - 0.014 14.3 0.1 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NmrA PF05368.8 KEY75007.1 - 0.018 14.3 0.0 0.12 11.6 0.0 2.1 1 1 0 1 1 1 0 NmrA-like family Epimerase_Csub PF13950.1 KEY75007.1 - 0.04 13.8 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit Sulfotransfer_3 PF13469.1 KEY75009.1 - 1.8e-05 25.7 0.0 2.6e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family PG_binding_2 PF08823.6 KEY75009.1 - 0.025 14.6 0.5 0.044 13.8 0.0 1.7 2 0 0 2 2 2 0 Putative peptidoglycan binding domain DUF500 PF04366.7 KEY75010.1 - 4.4e-43 145.7 0.0 7.4e-43 144.9 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) adh_short PF00106.20 KEY75011.1 - 1.3e-12 47.9 0.1 2.9e-12 46.8 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY75011.1 - 0.00012 21.7 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Fungal_trans_2 PF11951.3 KEY75012.1 - 3.2e-05 22.7 0.7 9.7e-05 21.1 0.0 2.0 3 0 0 3 3 3 1 Fungal specific transcription factor domain TMEM52 PF14979.1 KEY75012.1 - 0.14 12.0 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 Transmembrane 52 HD PF01966.17 KEY75014.1 - 6.6e-10 39.0 0.2 9.8e-10 38.4 0.1 1.2 1 0 0 1 1 1 1 HD domain Methyltransf_22 PF13383.1 KEY75015.1 - 6.6e-19 68.4 0.0 8.8e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 KEY75015.1 - 3.5e-06 27.0 0.0 4.9e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_18 PF12847.2 KEY75015.1 - 0.01 16.4 0.0 0.017 15.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF791 PF05631.9 KEY75016.1 - 9.5e-57 192.2 8.8 2.3e-56 191.0 6.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 KEY75016.1 - 6.3e-14 51.4 34.3 1e-13 50.7 23.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily His_Phos_2 PF00328.17 KEY75017.1 - 5.7e-28 98.2 0.0 7.9e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) F-box-like PF12937.2 KEY75020.1 - 2.2e-06 27.2 1.3 1.3e-05 24.7 0.0 2.7 2 1 0 2 2 2 1 F-box-like Peroxidase_2 PF01328.12 KEY75021.1 - 1.1e-24 86.7 0.3 8.1e-21 74.0 0.1 2.1 2 0 0 2 2 2 2 Peroxidase, family 2 D-ser_dehydrat PF14031.1 KEY75022.1 - 1.2e-21 76.6 0.1 2.3e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 KEY75022.1 - 3.1e-14 53.0 0.0 4.9e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF4470 PF14737.1 KEY75023.1 - 2.4e-27 94.5 0.0 5.5e-27 93.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) PPR_2 PF13041.1 KEY75023.1 - 0.034 14.1 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 PPR repeat family PPR PF01535.15 KEY75023.1 - 0.16 12.0 0.2 0.86 9.7 0.1 2.3 2 0 0 2 2 2 0 PPR repeat PhyH PF05721.8 KEY75024.1 - 5.6e-10 39.6 0.0 8.1e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KEY75024.1 - 9.7e-07 27.6 0.0 0.021 13.3 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) Sugar_tr PF00083.19 KEY75025.1 - 6.8e-71 239.1 31.1 8.4e-71 238.8 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY75025.1 - 6.8e-21 74.3 28.0 6.8e-21 74.3 19.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.6 KEY75026.1 - 0.04 13.6 6.6 0.097 12.4 4.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Citrate_synt PF00285.16 KEY75028.1 - 2.2e-87 293.1 0.0 2.6e-87 292.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase MFS_1 PF07690.11 KEY75030.1 - 6.2e-47 160.0 21.4 1.4e-40 139.1 8.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 KEY75030.1 - 7.8e-06 24.2 0.9 1.4e-05 23.4 0.7 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector TRI12 PF06609.8 KEY75030.1 - 1.4e-05 23.5 2.5 2.6e-05 22.6 1.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SPC12 PF06645.8 KEY75030.1 - 0.091 12.5 0.8 2.3 8.1 0.0 3.4 3 1 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Sex_peptide PF08138.6 KEY75030.1 - 0.27 11.1 2.6 1.5 8.7 0.1 3.5 4 0 0 4 4 4 0 Sex peptide (SP) family Pectate_lyase PF03211.8 KEY75031.1 - 6.6e-65 218.5 3.8 9.9e-65 217.9 2.6 1.1 1 0 0 1 1 1 1 Pectate lyase CBM_1 PF00734.13 KEY75031.1 - 9.5e-12 44.3 10.4 9.5e-12 44.3 7.2 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain Chlam_PMP PF02415.12 KEY75031.1 - 0.49 10.7 9.0 0.26 11.6 1.7 3.3 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Daxx PF03344.10 KEY75031.1 - 9.7 4.5 13.0 12 4.2 9.0 1.1 1 0 0 1 1 1 0 Daxx Family EnY2 PF10163.4 KEY75032.1 - 0.076 12.9 0.1 7.4 6.5 0.0 3.0 3 0 0 3 3 3 0 Transcription factor e(y)2 Zn_clus PF00172.13 KEY75034.1 - 0.00014 21.7 7.1 0.0003 20.6 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sensor PF13796.1 KEY75035.1 - 0.052 13.1 1.3 0.074 12.6 0.9 1.2 1 0 0 1 1 1 0 Putative sensor Peptidase_M28 PF04389.12 KEY75036.1 - 1.4e-26 93.3 0.0 2.2e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KEY75036.1 - 4.9e-07 29.4 0.0 9.5e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF1996 PF09362.5 KEY75037.1 - 2.4e-76 256.4 3.3 3e-76 256.1 2.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) PepSY_TM_2 PF13703.1 KEY75038.1 - 0.57 10.3 8.3 0.068 13.3 2.6 1.9 2 0 0 2 2 2 0 PepSY-associated TM helix adh_short PF00106.20 KEY75039.1 - 5.7e-12 45.8 0.1 7e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY75039.1 - 0.0037 16.9 0.0 0.0067 16.1 0.0 1.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEY75039.1 - 0.0061 16.3 0.0 0.0091 15.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KEY75040.1 - 2.7e-07 30.7 0.0 3.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KEY75040.1 - 0.00012 21.1 0.0 0.002 17.1 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein DapB_N PF01113.15 KEY75040.1 - 0.005 16.7 0.0 0.0089 15.9 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 KEY75040.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.16 KEY75040.1 - 0.022 14.2 0.0 0.044 13.2 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KEY75040.1 - 0.041 12.7 0.0 0.097 11.5 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 KEY75040.1 - 0.049 13.9 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 KEY75040.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Zn_clus PF00172.13 KEY75041.1 - 8.2e-06 25.6 8.6 1.6e-05 24.7 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY75041.1 - 0.00046 19.1 1.3 0.00093 18.1 0.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 KEY75042.1 - 6.3e-68 229.3 0.0 8.3e-68 228.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 KEY75043.1 - 8.9e-18 64.0 0.3 1.2e-17 63.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_32N PF00251.15 KEY75044.1 - 5.9e-152 505.3 6.8 1e-68 231.9 0.1 3.1 3 0 0 3 3 3 3 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KEY75044.1 - 1.3e-32 111.9 0.0 1.4e-17 63.8 0.0 2.6 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 KEY75044.1 - 0.028 14.1 7.1 1.7 8.8 0.1 4.0 3 0 0 3 3 3 0 BNR/Asp-box repeat NACHT PF05729.7 KEY75046.1 - 5.3e-19 68.4 0.0 9e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 KEY75046.1 - 8e-07 28.1 0.0 1.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.1 KEY75046.1 - 0.00039 20.3 0.0 0.0021 17.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KEY75046.1 - 0.002 18.3 0.0 0.0041 17.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEY75046.1 - 0.0045 17.7 3.5 0.017 15.9 0.3 2.9 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 KEY75046.1 - 0.0071 16.6 0.4 0.021 15.1 0.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 KEY75046.1 - 0.01 15.9 0.0 0.029 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KEY75046.1 - 0.021 14.7 0.4 0.45 10.4 0.0 2.8 2 1 0 3 3 3 0 AAA ATPase domain MobB PF03205.9 KEY75046.1 - 0.061 13.0 0.0 0.58 9.8 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KEY75046.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 KEY75046.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.1 KEY75046.1 - 0.35 10.4 0.0 0.66 9.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KEY75046.1 - 0.62 9.5 0.0 1.1 8.7 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation HET PF06985.6 KEY75047.1 - 5.8e-29 101.0 1.4 1e-28 100.2 0.9 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WD40 PF00400.27 KEY75048.1 - 8.6e-159 510.4 2.6 9.9e-14 50.6 0.0 12.9 13 0 0 13 13 13 12 WD domain, G-beta repeat NACHT PF05729.7 KEY75048.1 - 9.5e-23 80.6 0.7 2.7e-22 79.2 0.1 2.1 2 0 0 2 2 2 1 NACHT domain TruB_C PF09142.6 KEY75048.1 - 3.5e-06 26.5 26.2 7 6.3 0.0 9.9 11 0 0 11 11 11 5 tRNA Pseudouridine synthase II, C terminal Cytochrom_D1 PF02239.11 KEY75048.1 - 0.00082 17.7 0.0 16 3.6 0.0 4.6 1 1 2 5 5 5 2 Cytochrome D1 heme domain DUF2173 PF09941.4 KEY75048.1 - 0.021 14.7 3.4 1.1e+02 2.7 0.0 6.4 8 0 0 8 8 8 0 Uncharacterized conserved protein (DUF2173) AAA_19 PF13245.1 KEY75048.1 - 0.039 13.7 0.0 0.18 11.5 0.0 2.2 1 0 0 1 1 1 0 Part of AAA domain A1_Propeptide PF07966.7 KEY75048.1 - 0.47 10.3 2.2 3.8 7.4 0.0 3.7 4 0 0 4 4 4 0 A1 Propeptide WSC PF01822.14 KEY75051.1 - 3.2e-10 39.7 4.9 9.5e-10 38.2 3.4 1.9 1 0 0 1 1 1 1 WSC domain RPE65 PF03055.10 KEY75052.1 - 8.1e-134 446.8 0.0 9.2e-134 446.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Glyco_hydro_3 PF00933.16 KEY75054.1 - 2.6e-84 282.7 0.0 3.7e-84 282.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEY75054.1 - 1.9e-51 174.7 0.2 3.6e-51 173.8 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEY75054.1 - 5e-24 84.0 0.0 9.7e-24 83.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Bac_rhodopsin PF01036.13 KEY75055.1 - 9.6e-55 185.2 12.9 1.3e-54 184.8 8.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.1 KEY75055.1 - 4.1 6.7 16.4 0.41 10.0 0.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Meth_synt_2 PF01717.13 KEY75056.1 - 7.1e-23 81.0 0.0 1.8e-14 53.5 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KEY75056.1 - 1.5e-09 37.5 0.0 0.00029 20.1 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain adh_short PF00106.20 KEY75057.1 - 7.3e-16 58.5 1.6 1.2e-15 57.8 1.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEY75057.1 - 2.6e-05 23.9 0.6 5.7e-05 22.8 0.4 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KEY75057.1 - 0.041 12.7 0.0 0.1 11.4 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Glyco_hydro_61 PF03443.9 KEY75058.1 - 1.9e-57 194.5 0.0 2.5e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KEY75058.1 - 8.3e-09 34.9 14.3 8.3e-09 34.9 9.9 3.7 3 1 0 3 3 3 1 Fungal cellulose binding domain TB2_DP1_HVA22 PF03134.14 KEY75059.1 - 1.7e-30 104.6 7.9 2.3e-30 104.1 5.5 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Grp1_Fun34_YaaH PF01184.14 KEY75059.1 - 3.3 6.9 7.4 4.5 6.4 5.1 1.2 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family Mgm101p PF06420.7 KEY75060.1 - 1.1e-83 278.7 0.0 1.7e-83 278.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 TFIIA PF03153.8 KEY75060.1 - 8.9 6.0 12.9 12 5.6 8.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BPL_N PF09825.4 KEY75061.1 - 4.9e-135 450.0 0.0 6e-135 449.7 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 KEY75061.1 - 6.3e-13 48.8 0.1 1.6e-11 44.2 0.0 2.2 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family Pam16 PF03656.8 KEY75062.1 - 3e-31 107.8 0.4 3.7e-31 107.5 0.3 1.0 1 0 0 1 1 1 1 Pam16 Ribosomal_L13e PF01294.13 KEY75064.1 - 7.6e-60 201.4 3.5 1.1e-59 200.8 2.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e Na_H_Exchanger PF00999.16 KEY75064.1 - 1.7e-36 125.5 18.7 2.1e-36 125.2 13.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DAO PF01266.19 KEY75065.1 - 4.7e-38 131.0 0.4 6.3e-38 130.5 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Acetyltransf_7 PF13508.1 KEY75065.1 - 1.2e-06 28.5 0.0 2.8e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEY75065.1 - 3.3e-06 27.0 0.0 7.6e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pyr_redox_3 PF13738.1 KEY75065.1 - 3.4e-05 24.0 0.0 0.27 11.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEY75065.1 - 0.00014 21.8 2.3 0.00031 20.7 1.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Acetyltransf_10 PF13673.1 KEY75065.1 - 0.00091 19.3 0.0 0.0067 16.5 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KEY75065.1 - 0.0046 16.8 0.0 0.02 14.7 0.0 2.1 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Pyr_redox PF00070.22 KEY75065.1 - 0.0059 16.9 2.7 0.01 16.2 0.3 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_8 PF13523.1 KEY75065.1 - 0.029 14.2 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NAD_binding_9 PF13454.1 KEY75065.1 - 0.054 13.2 0.7 0.14 11.8 0.2 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KEY75065.1 - 0.15 11.9 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AA_permease_2 PF13520.1 KEY75066.1 - 3.2e-43 147.8 45.3 3.9e-43 147.5 31.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEY75066.1 - 6.9e-14 51.0 38.4 9.3e-14 50.6 26.6 1.1 1 0 0 1 1 1 1 Amino acid permease 6PF2K PF01591.13 KEY75067.1 - 0.082 11.9 0.0 10 5.0 0.0 2.6 3 0 0 3 3 3 0 6-phosphofructo-2-kinase Biopterin_H PF00351.16 KEY75067.1 - 0.12 11.1 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Biopterin-dependent aromatic amino acid hydroxylase Acetyltransf_9 PF13527.1 KEY75068.1 - 5.5e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEY75068.1 - 8.6e-05 22.4 0.0 0.0015 18.5 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEY75068.1 - 8.9e-05 22.5 0.0 0.00026 21.0 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain COX14 PF14880.1 KEY75069.1 - 1.3e-18 66.3 0.2 3.2e-18 65.0 0.1 1.7 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Cas_Cas02710 PF09670.5 KEY75069.1 - 0.069 11.7 0.2 0.09 11.3 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) PRP4 PF08799.6 KEY75069.1 - 0.094 11.9 0.2 0.21 10.8 0.1 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like DAHP_synth_1 PF00793.15 KEY75071.1 - 7.2e-95 316.7 0.1 8.3e-95 316.5 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family YIEGIA PF14045.1 KEY75071.1 - 0.017 13.7 0.2 0.028 13.0 0.1 1.2 1 0 0 1 1 1 0 YIEGIA protein PgaD PF13994.1 KEY75072.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 PgaD-like protein Imm6 PF14434.1 KEY75072.1 - 0.032 13.9 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Immunity protein Imm6 PAP_PilO PF06864.7 KEY75072.1 - 0.039 12.2 0.0 0.05 11.9 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Ribosomal_L50 PF10501.4 KEY75073.1 - 4.1e-13 49.2 0.0 6.9e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal subunit 39S Methyltransf_2 PF00891.13 KEY75074.1 - 4.3e-23 81.7 0.0 6.6e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase HTH_11 PF08279.7 KEY75074.1 - 0.0011 18.5 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_34 PF13601.1 KEY75074.1 - 0.0013 18.7 0.2 0.9 9.6 0.0 2.5 2 0 0 2 2 2 2 Winged helix DNA-binding domain Methyltransf_23 PF13489.1 KEY75074.1 - 0.0017 18.0 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HTH_24 PF13412.1 KEY75074.1 - 0.0032 16.8 0.0 0.0063 15.8 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 KEY75074.1 - 0.054 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 MarR family Methyltransf_23 PF13489.1 KEY75075.1 - 6.8e-19 68.1 0.0 1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY75075.1 - 4.9e-12 45.6 0.0 5.3e-11 42.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY75075.1 - 5e-09 36.5 0.0 9e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY75075.1 - 1.5e-08 35.1 0.1 1.7e-07 31.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY75075.1 - 3.3e-07 30.6 0.0 2.2e-06 28.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEY75075.1 - 8.3e-06 24.9 0.0 1.8e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 KEY75075.1 - 2.2e-05 24.7 0.0 5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY75075.1 - 0.001 19.0 0.0 0.0026 17.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY75075.1 - 0.0012 18.1 0.0 0.0033 16.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 KEY75075.1 - 0.002 18.1 0.0 0.0045 16.9 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase UPF0146 PF03686.8 KEY75075.1 - 0.046 13.5 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Ubie_methyltran PF01209.13 KEY75075.1 - 0.063 12.3 0.0 0.96 8.5 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family FmrO PF07091.6 KEY75075.1 - 0.13 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) PrmA PF06325.8 KEY75075.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Peptidase_S8 PF00082.17 KEY75077.1 - 2.8e-47 161.2 8.3 4.4e-47 160.5 5.8 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KEY75077.1 - 4e-13 49.7 0.0 7.4e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 HET PF06985.6 KEY75078.1 - 9.8e-20 71.1 7.8 2e-17 63.6 5.4 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Chromate_transp PF02417.10 KEY75079.1 - 5.2e-52 175.8 34.9 5.6e-30 104.1 8.2 2.4 3 0 0 3 3 3 2 Chromate transporter Pex24p PF06398.6 KEY75081.1 - 7.3e-98 327.6 3.3 7.3e-98 327.6 2.3 1.4 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin Apt1 PF10351.4 KEY75081.1 - 0.9 8.3 10.9 1.7 7.4 7.5 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Succ_DH_flav_C PF02910.15 KEY75082.1 - 0.017 15.0 0.1 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Fumarate reductase flavoprotein C-term Peptidase_U4 PF03419.8 KEY75082.1 - 4.6 6.2 5.6 6.2 5.7 3.8 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Ank_2 PF12796.2 KEY75084.1 - 1.1e-41 141.0 0.0 2.7e-17 62.8 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KEY75084.1 - 8.5e-37 123.1 1.0 3.8e-06 26.4 0.0 7.9 7 1 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 KEY75084.1 - 8.9e-36 121.6 2.6 2e-07 31.3 0.0 6.6 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY75084.1 - 3.7e-32 107.1 0.0 2.4e-05 24.1 0.0 7.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 KEY75084.1 - 1.1e-30 104.9 3.4 1.4e-07 31.4 0.1 6.3 4 2 2 6 6 6 5 Ankyrin repeats (many copies) FAD_binding_2 PF00890.19 KEY75085.1 - 6.3e-61 206.4 2.6 7.4e-61 206.2 1.8 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEY75085.1 - 3.7e-09 35.9 4.8 7.6e-09 34.9 3.3 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY75085.1 - 1.6e-08 34.4 0.5 4.5e-08 33.0 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KEY75085.1 - 9.5e-07 28.2 3.0 1.8e-06 27.3 2.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEY75085.1 - 3.1e-06 27.3 0.4 5.6e-06 26.5 0.3 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEY75085.1 - 6.4e-06 26.1 0.4 2e-05 24.5 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEY75085.1 - 2.8e-05 23.1 1.7 0.00027 19.9 0.4 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KEY75085.1 - 0.00011 21.3 2.0 0.00019 20.6 1.4 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KEY75085.1 - 0.0007 19.9 0.2 0.0028 18.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEY75085.1 - 0.00074 18.0 1.2 0.00074 18.0 0.8 2.5 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 KEY75085.1 - 0.0028 16.8 0.3 0.0079 15.3 0.1 1.8 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.16 KEY75085.1 - 0.02 14.4 0.1 0.041 13.4 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 KEY75085.1 - 0.045 12.6 0.4 0.071 12.0 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Strep_67kDa_ant PF06100.6 KEY75085.1 - 0.094 11.0 0.2 0.13 10.6 0.1 1.1 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family 3HCDH_N PF02737.13 KEY75085.1 - 0.097 12.3 0.2 0.22 11.1 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KEY75085.1 - 0.12 12.6 0.1 0.57 10.4 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Ank_2 PF12796.2 KEY75086.1 - 2.8e-19 69.2 0.0 1.6e-05 25.1 0.0 3.8 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEY75086.1 - 3.6e-09 35.9 0.0 0.017 15.3 0.0 5.4 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.25 KEY75086.1 - 1.1e-07 31.2 0.4 0.54 10.1 0.0 5.4 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 KEY75086.1 - 1.2e-05 25.3 0.0 1.3 9.4 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEY75086.1 - 3.7e-05 24.1 0.0 0.072 13.6 0.0 3.9 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Clr5 PF14420.1 KEY75086.1 - 0.035 14.0 0.3 0.17 11.7 0.2 2.1 1 1 0 1 1 1 0 Clr5 domain Ank_2 PF12796.2 KEY75087.1 - 1.3e-37 127.9 1.9 2.6e-21 75.7 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEY75087.1 - 9.4e-23 78.8 5.8 2.7e-07 30.0 0.1 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 KEY75087.1 - 1.4e-18 65.1 0.5 0.00029 20.8 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KEY75087.1 - 1.4e-16 60.1 2.3 0.00027 21.0 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEY75087.1 - 7.2e-12 45.4 0.4 7.1e-07 29.5 0.0 3.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Cu_amine_oxid PF01179.15 KEY75088.1 - 1.4e-85 287.5 0.4 2e-85 287.0 0.3 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 KEY75088.1 - 6.3e-08 32.4 0.0 2e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) adh_short PF00106.20 KEY75089.1 - 5.4e-12 45.9 0.0 7.5e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY75089.1 - 6.6e-07 29.3 0.0 8.4e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY75089.1 - 1.5e-05 24.7 0.1 2.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEY75089.1 - 5.6e-05 22.7 0.0 8.2e-05 22.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY75089.1 - 0.031 14.2 1.3 0.064 13.2 0.7 1.6 2 0 0 2 2 2 0 NADH(P)-binding AMP-binding PF00501.23 KEY75091.1 - 3.9e-75 252.8 0.0 5.6e-75 252.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KEY75091.1 - 0.00031 19.7 0.4 0.00031 19.7 0.3 1.8 2 0 0 2 2 2 1 Condensation domain p450 PF00067.17 KEY75092.1 - 3e-61 207.3 0.0 3.9e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SMRP1 PF15181.1 KEY75092.1 - 0.033 13.5 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Spermatid-specific manchette-related protein 1 Oscp1 PF10188.4 KEY75093.1 - 0.12 12.1 0.1 0.56 10.0 0.0 1.8 1 1 0 2 2 2 0 Organic solute transport protein 1 Pribosyltran PF00156.22 KEY75094.1 - 1.4e-09 37.7 0.2 7.7e-09 35.3 0.2 1.9 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Oxidored-like PF09791.4 KEY75096.1 - 5.1e-25 86.6 3.8 1.2e-24 85.4 2.7 1.7 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Epimerase_2 PF02350.14 KEY75097.1 - 0.028 13.1 0.1 0.044 12.5 0.1 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase CENP-P PF13096.1 KEY75097.1 - 0.19 11.0 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P DPM3 PF08285.6 KEY75098.1 - 8.9e-32 108.7 0.1 9.8e-32 108.6 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF3618 PF12277.3 KEY75098.1 - 0.19 11.7 1.2 0.33 11.0 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) p450 PF00067.17 KEY75099.1 - 5.5e-51 173.5 0.0 6.9e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GCR1_C PF12550.3 KEY75100.1 - 2e-11 43.5 0.0 4e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Dicty_REP PF05086.7 KEY75101.1 - 0.46 8.1 3.0 0.58 7.8 2.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tir_receptor_C PF07489.6 KEY75101.1 - 1.4 8.6 7.3 2.3 7.9 5.1 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Baculo_PEP_C PF04513.7 KEY75104.1 - 0.0049 16.6 4.4 0.046 13.5 0.2 2.2 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Cauli_VI PF01693.11 KEY75105.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Caulimovirus viroplasmin DUF2353 PF09789.4 KEY75106.1 - 0.017 14.3 0.2 0.025 13.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) TAXi_N PF14543.1 KEY75106.1 - 0.036 14.0 2.4 0.066 13.1 1.7 1.5 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal DUF1664 PF07889.7 KEY75106.1 - 0.12 12.1 0.8 0.22 11.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Prefoldin_3 PF13758.1 KEY75106.1 - 0.15 11.8 1.1 0.39 10.5 0.7 1.7 1 1 0 1 1 1 0 Prefoldin subunit IncA PF04156.9 KEY75106.1 - 0.16 11.5 2.5 0.26 10.8 1.7 1.2 1 0 0 1 1 1 0 IncA protein zf-CCCH PF00642.19 KEY75106.1 - 0.16 11.7 0.3 0.16 11.7 0.2 2.6 2 1 1 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Sugar_tr PF00083.19 KEY75107.1 - 2.8e-72 243.7 25.7 3.5e-72 243.4 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY75107.1 - 1.5e-30 106.1 57.1 1.9e-22 79.4 11.8 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.8 KEY75107.1 - 1.3e-05 23.6 2.1 1.3e-05 23.6 1.5 2.5 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_1 PF00232.13 KEY75108.1 - 6.9e-146 486.0 0.0 8.5e-146 485.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 KEY75108.1 - 0.018 14.5 0.0 0.042 13.2 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase catalytic core Fungal_trans PF04082.13 KEY75109.1 - 1.2e-14 53.8 0.3 2.2e-13 49.6 0.2 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY75109.1 - 4.3e-07 29.7 9.7 7.5e-07 28.9 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TYA PF01021.14 KEY75109.1 - 0.23 11.6 5.8 0.11 12.7 1.7 2.1 2 0 0 2 2 2 0 TYA transposon protein HET PF06985.6 KEY75111.1 - 2e-23 83.1 0.3 3.7e-23 82.2 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 KEY75114.1 - 4.2e-20 72.3 0.5 5.7e-20 71.9 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEY75114.1 - 1.2e-09 38.3 0.0 1.5e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEY75114.1 - 0.00032 20.4 0.4 0.0005 19.7 0.3 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KEY75114.1 - 0.00067 18.8 0.0 0.00095 18.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Pkinase PF00069.20 KEY75115.1 - 2.9e-14 52.8 0.0 4.3e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY75115.1 - 2.4e-05 23.5 0.0 4.8e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase zf-LITAF-like PF10601.4 KEY75116.1 - 5.1e-05 23.0 0.0 8.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain FAD_binding_4 PF01565.18 KEY75117.1 - 3.8e-20 71.7 1.3 6.5e-20 71.0 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY75117.1 - 0.0018 18.1 0.1 0.0042 16.9 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like GHL6 PF14871.1 KEY75118.1 - 9.4e-23 80.6 0.0 1.6e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 DUF187 PF02638.10 KEY75118.1 - 2.7e-06 26.4 0.0 4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 Glyco_hydro_42M PF08532.5 KEY75118.1 - 1.8e-05 24.0 0.1 4.4e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Beta-galactosidase trimerisation domain Glyco_hydro_42 PF02449.10 KEY75118.1 - 2.5e-05 23.6 0.3 5.2e-05 22.5 0.2 1.5 1 0 0 1 1 1 1 Beta-galactosidase HET PF06985.6 KEY75119.1 - 1.3e-36 125.8 0.7 2.1e-36 125.1 0.5 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 KEY75120.1 - 4.2e-25 88.2 60.7 1.4e-24 86.4 40.4 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEY75120.1 - 3.6e-06 25.8 17.0 3.6e-06 25.8 11.8 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter adh_short PF00106.20 KEY75121.1 - 1.6e-15 57.4 0.6 6.2e-15 55.5 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY75121.1 - 7e-06 25.8 0.3 1.9e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 KR domain DUF3237 PF11578.3 KEY75122.1 - 1.6e-16 59.9 0.0 2e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) CoA_binding_3 PF13727.1 KEY75122.1 - 0.046 13.5 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 CoA-binding domain adh_short PF00106.20 KEY75123.1 - 4.3e-06 26.7 0.4 7.9e-06 25.8 0.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KEY75123.1 - 2.5e-05 23.8 0.0 3.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEY75123.1 - 0.0019 18.2 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KEY75123.1 - 0.014 14.6 0.2 0.025 13.8 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family adh_short_C2 PF13561.1 KEY75123.1 - 0.045 13.5 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase 2-Hacid_dh_C PF02826.14 KEY75123.1 - 0.12 11.5 0.0 0.61 9.2 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ketoacyl-synt PF00109.21 KEY75124.1 - 1.1e-67 228.1 0.0 2.6e-67 227.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 KEY75124.1 - 2.1e-66 224.1 0.4 5.9e-66 222.6 0.3 1.9 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KEY75124.1 - 9.9e-66 222.2 0.4 1.9e-65 221.2 0.3 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KEY75124.1 - 1.9e-58 197.1 3.3 6.7e-58 195.3 1.8 2.5 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KEY75124.1 - 3.2e-49 167.0 3.6 3.2e-49 167.0 2.5 3.1 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KEY75124.1 - 1.8e-28 98.7 1.9 2.5e-28 98.2 0.2 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KEY75124.1 - 1.5e-05 24.5 5.3 4.1e-05 23.1 0.2 3.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEY75124.1 - 5.3e-05 22.9 0.4 0.00013 21.6 0.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 KEY75124.1 - 5.5e-05 22.2 0.4 0.00012 21.2 0.3 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 KEY75124.1 - 0.012 15.8 0.0 0.032 14.4 0.0 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site Pyr_redox_3 PF13738.1 KEY75126.1 - 2.8e-26 92.8 0.0 2.7e-25 89.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEY75126.1 - 1.3e-10 40.1 0.0 0.00011 20.5 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KEY75126.1 - 9.2e-09 34.6 0.0 2e-07 30.2 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KEY75126.1 - 2.6e-08 33.7 0.0 0.004 16.9 0.0 3.8 3 1 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KEY75126.1 - 3.2e-06 27.0 0.3 1.8e-05 24.6 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KEY75126.1 - 2.3e-05 24.3 0.0 7.2e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEY75126.1 - 0.00018 20.0 0.0 0.16 10.4 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.7 KEY75126.1 - 0.00028 19.9 0.0 0.0034 16.3 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 KEY75126.1 - 0.006 15.6 0.1 0.29 10.1 0.0 2.4 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.22 KEY75126.1 - 0.025 14.9 0.1 12 6.3 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEY75126.1 - 0.058 12.3 0.0 1.5 7.6 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_4 PF01565.18 KEY75127.1 - 1.6e-17 63.2 2.2 2.6e-17 62.5 1.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEY75127.1 - 4.7e-10 39.2 0.1 4.7e-10 39.2 0.1 2.2 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 KEY75127.1 - 0.01 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_3 PF01494.14 KEY75128.1 - 2.1e-27 96.1 0.0 4.7e-27 94.9 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KEY75128.1 - 7.3e-06 25.9 0.1 1.7e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEY75128.1 - 3.2e-05 22.9 1.5 0.0015 17.5 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEY75128.1 - 0.0013 17.7 1.1 0.0022 16.9 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 KEY75128.1 - 0.0053 15.4 0.0 0.0092 14.6 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase Amino_oxidase PF01593.19 KEY75128.1 - 0.012 14.7 0.0 0.41 9.6 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.12 KEY75128.1 - 0.019 14.0 0.1 0.036 13.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 KEY75128.1 - 0.02 14.4 0.3 0.037 13.5 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 KEY75128.1 - 0.02 15.2 0.7 0.052 13.9 0.5 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEY75128.1 - 0.054 13.5 0.3 0.11 12.5 0.2 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEY75128.1 - 0.081 11.8 0.2 1 8.2 0.1 2.4 2 1 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEY75128.1 - 0.088 12.6 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KEY75128.1 - 0.11 11.3 0.0 0.75 8.5 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase HI0933_like PF03486.9 KEY75128.1 - 0.11 10.8 0.5 0.27 9.6 0.3 1.6 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 KEY75128.1 - 0.23 10.3 0.8 0.36 9.6 0.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF3237 PF11578.3 KEY75129.1 - 1.2e-16 60.3 0.0 1.4e-16 60.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Fungal_trans PF04082.13 KEY75130.1 - 1.9e-18 66.3 0.0 4.1e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEY75130.1 - 6.5e-10 38.7 10.1 1.2e-09 37.8 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0167 PF03691.9 KEY75131.1 - 0.012 15.0 1.9 0.017 14.5 1.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) Abhydrolase_6 PF12697.2 KEY75132.1 - 1e-32 113.8 0.0 1.7e-32 113.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEY75132.1 - 3.8e-17 62.6 0.1 1.6e-16 60.5 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEY75132.1 - 1e-12 48.0 0.0 1.8e-11 43.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KEY75132.1 - 2.7e-06 27.1 0.0 4.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 KEY75132.1 - 0.0054 15.2 0.0 0.0086 14.5 0.0 1.2 1 0 0 1 1 1 1 Ndr family AXE1 PF05448.7 KEY75132.1 - 0.023 13.2 0.0 0.3 9.5 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 KEY75132.1 - 0.037 13.4 0.0 5.9 6.2 0.0 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) HD PF01966.17 KEY75133.1 - 0.0027 17.6 0.0 0.0038 17.2 0.0 1.2 1 0 0 1 1 1 1 HD domain DUF4066 PF13278.1 KEY75134.1 - 1.1e-24 86.5 0.1 1.7e-24 85.9 0.1 1.3 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KEY75134.1 - 2.8e-10 39.8 0.0 4.3e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 KEY75134.1 - 0.12 11.7 0.0 0.16 11.4 0.0 1.3 1 1 0 1 1 1 0 Glutamine amidotransferase class-I GATase_3 PF07685.9 KEY75134.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Lipase_GDSL_2 PF13472.1 KEY75135.1 - 7.6e-18 65.2 1.8 1e-17 64.8 1.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KEY75135.1 - 1.3e-09 38.2 1.4 7.6e-09 35.7 1.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4470 PF14737.1 KEY75136.1 - 3.8e-24 84.3 0.0 9.5e-24 83.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 KEY75136.1 - 4.5e-05 23.2 7.5 0.00012 21.8 5.2 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 KEY75136.1 - 0.005 16.4 2.5 0.013 15.0 1.7 1.8 1 0 0 1 1 1 1 HIT zinc finger zf-Mss51 PF13824.1 KEY75136.1 - 0.021 14.6 4.0 0.049 13.4 2.8 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 RTA1 PF04479.8 KEY75137.1 - 9.2e-56 188.8 11.6 1.7e-55 187.9 8.0 1.4 1 0 0 1 1 1 1 RTA1 like protein Sulfotransfer_3 PF13469.1 KEY75138.1 - 2.1e-05 25.4 0.1 3.4e-05 24.8 0.1 1.3 1 1 0 1 1 1 1 Sulfotransferase family GATase_5 PF13507.1 KEY75140.1 - 2e-98 328.4 0.0 2.8e-98 327.9 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 KEY75140.1 - 3e-39 134.4 0.5 9.6e-21 74.3 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KEY75140.1 - 2e-22 79.2 1.3 8.2e-22 77.2 0.0 2.7 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain Thioredoxin PF00085.15 KEY75141.1 - 1.2e-27 95.6 0.0 1.4e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KEY75141.1 - 8.7e-07 29.1 0.3 1e-05 25.7 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KEY75141.1 - 2.3e-05 24.2 0.0 2.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 KEY75141.1 - 4e-05 23.6 0.1 0.0071 16.4 0.1 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 KEY75141.1 - 0.00034 20.1 0.0 0.00037 20.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 KEY75141.1 - 0.028 13.9 0.1 0.061 12.8 0.1 1.5 1 1 1 2 2 2 0 Redoxin AhpC-TSA PF00578.16 KEY75141.1 - 0.035 13.7 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family KaiB PF07689.7 KEY75141.1 - 0.065 12.7 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 KaiB domain DUF953 PF06110.6 KEY75141.1 - 0.097 12.1 0.2 0.73 9.2 0.1 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Sugar_tr PF00083.19 KEY75142.1 - 9.3e-97 324.4 16.3 1.1e-96 324.1 11.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEY75142.1 - 4.4e-19 68.4 29.9 2.3e-16 59.4 13.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEY75142.1 - 4.9e-08 31.8 24.7 2.3e-06 26.2 5.9 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein UNC-93 PF05978.11 KEY75142.1 - 1.8 8.0 10.1 11 5.5 0.1 3.5 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 Ribonuc_L-PSP PF01042.16 KEY75143.1 - 2.7e-18 65.8 0.0 5.6e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP PAP_assoc PF03828.14 KEY75143.1 - 4.9e-09 35.9 0.0 1.1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KEY75143.1 - 3.4e-08 33.7 0.0 7.2e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain GMC_oxred_N PF00732.14 KEY75144.1 - 2.4e-58 197.6 0.0 3.3e-58 197.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEY75144.1 - 4.8e-34 117.7 0.1 1.5e-33 116.1 0.1 1.8 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KEY75144.1 - 2.5e-05 23.3 0.2 5.3e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEY75144.1 - 0.00014 21.8 0.1 0.00032 20.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEY75144.1 - 0.0002 20.3 0.1 0.0069 15.2 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KEY75144.1 - 0.00064 18.7 0.1 0.00099 18.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEY75144.1 - 0.013 15.3 0.0 0.032 14.1 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KEY75144.1 - 0.063 11.9 0.0 0.11 11.0 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Hormone_recep PF00104.25 KEY75144.1 - 0.063 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor HI0933_like PF03486.9 KEY75144.1 - 0.11 10.9 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein F-box-like PF12937.2 KEY75145.1 - 0.0018 17.9 1.8 0.0039 16.8 1.2 1.6 1 0 0 1 1 1 1 F-box-like GSK-3_bind PF05350.7 KEY75145.1 - 0.16 11.4 0.5 0.26 10.6 0.4 1.3 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding Glyco_hydro_61 PF03443.9 KEY75146.1 - 2.2e-39 135.5 0.0 3e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 TPR_12 PF13424.1 KEY75147.1 - 2e-06 27.6 0.2 1.7e-05 24.6 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEY75147.1 - 0.0052 16.3 0.1 0.014 15.0 0.0 1.7 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 KEY75147.1 - 0.0097 15.4 1.6 0.022 14.3 1.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 KEY75147.1 - 0.016 15.0 0.6 0.055 13.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEY75147.1 - 0.024 14.5 1.9 0.073 13.0 1.3 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 KEY75148.1 - 1.1e-09 37.5 0.1 2.9e-09 36.2 0.1 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily MCPVI PF02993.9 KEY75149.1 - 3.3 7.7 6.5 6.6 6.8 4.5 1.4 1 0 0 1 1 1 0 Minor capsid protein VI PNP_UDP_1 PF01048.15 KEY75150.1 - 1.4e-09 37.2 0.1 5e-09 35.4 0.1 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily Glyco_hyd_65N_2 PF14498.1 KEY75151.1 - 5.1e-05 23.0 0.0 8.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Ank_2 PF12796.2 KEY75153.1 - 2.4e-71 236.1 4.6 1.9e-14 53.7 0.0 5.3 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 KEY75153.1 - 8.1e-43 142.1 12.1 1.3e-07 31.0 0.2 8.6 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 KEY75153.1 - 3e-34 116.7 3.8 8.3e-07 29.3 0.0 7.0 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEY75153.1 - 8.7e-31 105.2 8.6 1.6e-09 37.6 0.0 8.1 7 1 2 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY75153.1 - 2e-29 98.6 6.4 0.00052 19.9 0.1 8.6 9 0 0 9 9 9 7 Ankyrin repeat F-box-like PF12937.2 KEY75153.1 - 0.046 13.4 0.1 2.9 7.6 0.0 2.4 2 0 0 2 2 2 0 F-box-like HMGL-like PF00682.14 KEY75157.1 - 2.5e-53 181.1 4.6 9.3e-33 113.8 0.0 2.6 2 1 1 3 3 3 2 HMGL-like Trp_syntA PF00290.15 KEY75157.1 - 0.00045 18.8 0.0 0.36 9.3 0.0 2.4 2 0 0 2 2 2 2 Tryptophan synthase alpha chain GcpE PF04551.9 KEY75157.1 - 0.062 12.1 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 GcpE protein Metallophos_2 PF12850.2 KEY75158.1 - 2e-07 30.9 0.2 3.9e-07 30.0 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KEY75158.1 - 3.6e-06 26.5 1.1 8.7e-06 25.2 0.8 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF523 PF04463.7 KEY75158.1 - 0.018 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF523) Aromatic_hydrox PF11723.3 KEY75158.1 - 0.071 12.3 0.3 0.11 11.7 0.2 1.3 1 0 0 1 1 1 0 Homotrimeric ring hydroxylase NmrA PF05368.8 KEY75159.1 - 5e-30 104.4 0.0 1.4e-29 103.0 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEY75159.1 - 4e-13 49.7 0.1 5.2e-13 49.4 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KEY75159.1 - 1.1e-05 25.4 1.2 1.9e-05 24.6 0.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KEY75159.1 - 9e-05 22.0 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 KEY75159.1 - 0.0052 17.1 0.3 0.011 16.1 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KEY75159.1 - 0.0058 16.6 0.0 0.016 15.2 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain Herpes_IR6 PF06307.7 KEY75159.1 - 0.014 14.7 0.1 2.1 7.6 0.1 2.3 2 0 0 2 2 2 0 Herpesvirus IR6 protein 3Beta_HSD PF01073.14 KEY75159.1 - 0.016 13.9 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 KEY75159.1 - 0.028 13.3 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase KR PF08659.5 KEY75159.1 - 0.064 12.9 0.2 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 KR domain LytR_C PF13399.1 KEY75159.1 - 0.073 13.4 1.5 11 6.4 0.0 2.3 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator Methyltransf_23 PF13489.1 KEY75160.1 - 1.4e-20 73.6 0.0 2.2e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEY75160.1 - 8.7e-10 38.3 0.0 6.5e-09 35.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEY75160.1 - 1.4e-07 32.0 0.0 7.5e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEY75160.1 - 2.5e-07 31.0 0.0 5.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEY75160.1 - 0.00069 20.0 0.0 0.0021 18.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEY75160.1 - 0.0021 18.3 0.0 0.0047 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEY75160.1 - 0.0035 17.3 0.0 0.0089 16.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEY75160.1 - 0.0055 16.0 0.0 0.016 14.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 KEY75160.1 - 0.011 14.7 0.0 0.026 13.6 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 KEY75160.1 - 0.037 13.0 0.0 0.09 11.8 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_16 PF10294.4 KEY75160.1 - 0.044 13.2 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 KEY75160.1 - 0.066 12.3 0.0 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 KEY75160.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase FtsJ PF01728.14 KEY75160.1 - 0.16 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Yip1 PF04893.12 KEY75162.1 - 0.00047 19.7 14.8 0.064 12.7 6.3 2.6 2 1 0 2 2 2 2 Yip1 domain RCC1 PF00415.13 KEY75163.1 - 1.5e-71 236.4 3.9 3.6e-13 49.4 0.1 7.8 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEY75163.1 - 3.9e-39 131.4 37.0 2.6e-10 39.6 1.0 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat TFIIA PF03153.8 KEY75163.1 - 0.0016 18.4 6.7 0.0027 17.6 4.6 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CBM_X PF06204.6 KEY75163.1 - 0.28 10.7 3.1 13 5.3 0.5 2.6 2 0 0 2 2 2 0 Putative carbohydrate binding domain Trypsin PF00089.21 KEY75165.1 - 0.0012 18.4 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 KEY75165.1 - 0.003 17.5 0.1 0.006 16.5 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain HET PF06985.6 KEY75167.1 - 1.1e-29 103.3 5.2 1.8e-29 102.6 3.6 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 KEY75169.1 - 1.9e-33 115.6 30.5 4.6e-33 114.3 21.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Cu_amine_oxid PF01179.15 KEY75170.1 - 7.9e-169 561.7 0.0 9.6e-169 561.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KEY75170.1 - 6.5e-22 77.5 0.1 1.2e-21 76.6 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KEY75170.1 - 3.8e-12 46.1 0.0 7.8e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain HpcH_HpaI PF03328.9 KEY75173.1 - 2.7e-25 88.5 0.0 3e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family P2 PF07194.6 KEY75173.1 - 0.1 12.4 0.2 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 P2 response regulator binding domain Nucleoplasmin PF03066.10 KEY75174.1 - 0.31 10.5 6.9 0.55 9.7 4.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 KEY75174.1 - 3.4 7.9 9.8 3.7 7.8 5.9 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CHAT PF12770.2 KEY75175.1 - 8.5e-11 41.5 0.0 2.2e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 CHAT domain NACHT PF05729.7 KEY75175.1 - 2.8e-09 36.8 0.1 9.8e-09 35.0 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KEY75175.1 - 0.00013 22.1 0.0 0.00031 20.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEY75175.1 - 0.0023 17.9 0.0 0.005 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain UPF0079 PF02367.12 KEY75175.1 - 0.18 11.4 0.1 0.41 10.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CorA PF01544.13 KEY75176.1 - 5.2e-09 35.5 0.1 9.4e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein FMO-like PF00743.14 KEY75177.1 - 6.7e-32 110.3 0.0 2.7e-15 55.5 0.0 3.3 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KEY75177.1 - 3.1e-23 82.9 1.2 2.2e-22 80.1 0.7 2.2 2 1 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEY75177.1 - 8.5e-14 51.2 4.8 2.7e-06 26.5 1.3 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KEY75177.1 - 4.5e-10 39.1 0.7 1.3e-05 24.4 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KEY75177.1 - 1.6e-09 37.6 0.0 4.9e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KEY75177.1 - 2.6e-09 37.2 0.0 7.9e-08 32.4 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEY75177.1 - 6.8e-08 32.8 2.1 0.00013 22.3 0.6 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEY75177.1 - 2.1e-07 30.1 1.6 2.1e-06 26.8 0.1 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KEY75177.1 - 4.2e-06 26.6 5.4 0.00066 19.4 0.1 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.9 KEY75177.1 - 5e-06 25.2 0.3 0.0026 16.2 0.3 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 KEY75177.1 - 1.9e-05 23.7 7.8 0.00076 18.4 1.1 2.3 2 1 0 2 2 2 2 FAD binding domain NAD_binding_10 PF13460.1 KEY75177.1 - 7.4e-05 22.8 0.1 0.033 14.1 0.0 2.6 1 1 1 2 2 2 1 NADH(P)-binding ApbA PF02558.11 KEY75177.1 - 0.0011 18.4 0.1 0.057 12.8 0.0 2.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 KEY75177.1 - 0.0015 17.6 2.1 0.0024 16.9 0.4 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KEY75177.1 - 0.0043 16.2 2.7 0.013 14.6 1.9 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KEY75177.1 - 0.011 14.8 0.7 0.021 13.9 0.5 1.3 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 KEY75177.1 - 0.025 14.2 1.8 0.055 13.1 1.3 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 KEY75177.1 - 0.027 13.3 2.5 0.034 12.9 0.8 1.8 3 0 0 3 3 3 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 KEY75177.1 - 0.16 12.0 2.8 7.8 6.5 0.2 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KEY75177.1 - 0.2 11.9 0.5 8.2 6.7 0.0 2.7 3 0 0 3 3 2 0 Putative NAD(P)-binding IncA PF04156.9 KEY75178.1 - 2.6e-05 23.9 87.9 0.0022 17.6 18.8 5.0 1 1 4 5 5 5 3 IncA protein Spc7 PF08317.6 KEY75178.1 - 0.00032 19.4 25.5 0.00032 19.4 17.7 3.9 1 1 1 3 3 3 2 Spc7 kinetochore protein GAS PF13851.1 KEY75178.1 - 0.0025 17.0 80.3 0.02 14.0 12.2 4.9 1 1 4 5 5 5 3 Growth-arrest specific micro-tubule binding THOC7 PF05615.8 KEY75178.1 - 0.015 15.5 6.5 0.015 15.5 4.5 6.0 2 2 3 5 5 3 0 Tho complex subunit 7 Reo_sigmaC PF04582.7 KEY75178.1 - 0.015 14.4 37.8 0.044 12.9 7.3 4.1 2 2 1 4 4 4 0 Reovirus sigma C capsid protein bZIP_1 PF00170.16 KEY75178.1 - 0.021 14.7 0.8 0.021 14.7 0.5 8.6 6 4 3 9 9 9 0 bZIP transcription factor ADIP PF11559.3 KEY75178.1 - 0.041 13.7 85.9 0.81 9.5 2.6 6.4 2 2 3 5 5 5 0 Afadin- and alpha -actinin-Binding FtsH_ext PF06480.10 KEY75178.1 - 0.094 12.9 0.8 0.43 10.7 0.5 2.2 1 0 0 1 1 1 0 FtsH Extracellular ATG16 PF08614.6 KEY75178.1 - 0.14 12.0 91.4 0.083 12.7 9.3 5.6 2 2 3 5 5 5 0 Autophagy protein 16 (ATG16) Shugoshin_N PF07558.6 KEY75178.1 - 0.26 11.0 11.2 1.2 8.9 0.6 3.8 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region TMF_DNA_bd PF12329.3 KEY75178.1 - 0.59 9.9 94.6 0.76 9.6 8.3 7.9 3 3 3 7 7 7 0 TATA element modulatory factor 1 DNA binding SAP PF02037.22 KEY75178.1 - 0.78 9.3 7.3 0.17 11.3 0.5 3.4 3 0 0 3 3 3 0 SAP domain VWA_2 PF13519.1 KEY75179.1 - 2.6e-07 30.8 0.0 0.0075 16.3 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA PF00092.23 KEY75179.1 - 0.00082 19.1 0.0 0.0099 15.6 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain Peptidase_C1 PF00112.18 KEY75179.1 - 0.11 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Papain family cysteine protease zinc_ribbon_5 PF13719.1 KEY75179.1 - 6.3 6.4 5.7 1.9 8.1 0.5 2.2 1 1 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KEY75179.1 - 6.7 6.4 5.8 2.4 7.9 0.6 2.2 1 1 0 2 2 2 0 zinc-ribbon domain MFS_1 PF07690.11 KEY75181.1 - 1e-13 50.7 34.4 1e-13 50.7 23.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Dynamin_N PF00350.18 KEY75182.1 - 7e-29 100.7 0.2 1.3e-28 99.8 0.1 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KEY75182.1 - 0.00077 19.3 0.1 0.0034 17.3 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEY75182.1 - 0.0083 16.6 0.1 0.028 14.9 0.0 1.9 1 1 1 2 2 2 1 Miro-like protein DUF1917 PF08939.5 KEY75182.1 - 0.059 13.1 0.4 0.1 12.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) AAA_23 PF13476.1 KEY75182.1 - 0.085 13.1 0.1 0.15 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain GED PF02212.13 KEY75183.1 - 0.0037 17.1 0.9 0.0054 16.6 0.1 1.6 2 0 0 2 2 2 1 Dynamin GTPase effector domain Ras_bdg_2 PF14847.1 KEY75183.1 - 0.071 13.0 0.6 0.15 11.9 0.4 1.9 1 1 0 1 1 1 0 Ras-binding domain of Byr2 Surf_Ag_VNR PF07244.10 KEY75183.1 - 0.084 13.3 1.0 0.37 11.2 0.0 2.3 2 1 1 3 3 3 0 Surface antigen variable number repeat Toprim_2 PF13155.1 KEY75183.1 - 0.14 12.5 0.3 0.21 11.9 0.2 1.4 1 0 0 1 1 1 0 Toprim-like Annexin PF00191.15 KEY75184.1 - 4.3e-42 141.8 0.6 2.7e-11 43.2 0.0 4.4 4 0 0 4 4 4 4 Annexin TPR_8 PF13181.1 KEY75184.1 - 0.092 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat HET PF06985.6 KEY75186.1 - 9.6e-31 106.8 0.3 1.9e-30 105.8 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DAO PF01266.19 KEY75187.1 - 6.9e-18 64.6 4.4 8.4e-18 64.3 3.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KEY75187.1 - 0.091 12.3 0.2 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Solute_trans_a PF03619.11 KEY75188.1 - 1e-61 208.7 18.0 1.2e-61 208.4 12.4 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Colicin_V PF02674.11 KEY75188.1 - 0.85 9.4 8.9 0.29 10.9 1.9 2.8 3 0 0 3 3 3 0 Colicin V production protein UPF0114 PF03350.11 KEY75188.1 - 3.4 7.6 8.6 6.1 6.7 1.8 3.4 4 0 0 4 4 4 0 Uncharacterized protein family, UPF0114 Cyto_ox_2 PF02322.10 KEY75190.1 - 0.007 15.5 1.8 0.007 15.5 1.3 1.5 1 1 0 1 1 1 1 Cytochrome oxidase subunit II DUF368 PF04018.8 KEY75190.1 - 0.008 15.3 0.7 0.01 15.0 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF368) DUF998 PF06197.8 KEY75190.1 - 0.034 13.4 6.4 0.026 13.8 3.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF998) Chromate_transp PF02417.10 KEY75190.1 - 0.14 11.7 3.2 0.22 11.1 2.2 1.3 1 0 0 1 1 1 0 Chromate transporter p450 PF00067.17 KEY75191.1 - 5.7e-66 222.9 0.0 7.1e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3188 PF11384.3 KEY75191.1 - 0.081 12.5 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) Corona_S1 PF01600.11 KEY75192.1 - 0.11 10.7 0.0 0.17 10.1 0.0 1.2 1 0 0 1 1 1 0 Coronavirus S1 glycoprotein HET PF06985.6 KEY75193.1 - 9.5e-29 100.3 3.8 2.5e-28 98.9 2.6 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) OST3_OST6 PF04756.8 KEY75193.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family Con-6 PF10346.4 KEY75194.1 - 1.9e-12 46.3 0.3 4.3e-12 45.2 0.2 1.7 1 0 0 1 1 1 1 Conidiation protein 6 Beta-lactamase PF00144.19 KEY75197.1 - 6.9e-41 140.3 0.7 1e-40 139.7 0.5 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 KEY75197.1 - 0.046 12.9 0.0 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Glyco_hydro_67N PF03648.9 KEY75198.1 - 0.011 15.7 0.0 0.031 14.2 0.0 1.8 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus CBM_1 PF00734.13 KEY75199.1 - 7.2e-12 44.7 4.4 1.4e-11 43.7 3.1 1.5 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KEY75199.1 - 0.48 10.5 2.2 0.7 9.9 1.6 1.3 1 0 0 1 1 1 0 Toxin 7 FAT PF02259.18 KEY75200.1 - 2.3e-130 434.7 6.8 5.8e-130 433.3 4.7 1.8 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 KEY75200.1 - 2.9e-62 210.1 0.3 5.3e-62 209.3 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 KEY75200.1 - 5.5e-61 205.1 2.7 6.4e-60 201.7 0.3 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 KEY75200.1 - 1.5e-43 146.9 3.5 1.6e-43 146.8 0.2 3.0 2 0 0 2 2 2 1 Rapamycin binding domain HEAT_2 PF13646.1 KEY75200.1 - 9.8e-20 70.6 8.9 7.7e-06 26.1 0.1 8.4 7 1 2 9 9 9 4 HEAT repeats HEAT PF02985.17 KEY75200.1 - 8.5e-17 59.6 9.9 0.012 15.5 0.0 10.9 11 0 0 11 11 11 4 HEAT repeat FATC PF02260.15 KEY75200.1 - 2.6e-14 52.3 0.1 6.1e-14 51.1 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.1 KEY75200.1 - 1.1e-13 51.2 8.2 1.7e-06 28.3 0.0 10.1 8 2 2 10 10 10 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KEY75200.1 - 4e-09 36.7 0.1 15 6.0 0.0 7.8 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region Sugar_tr PF00083.19 KEY75201.1 - 5.2e-94 315.3 14.9 7e-94 314.9 10.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter PRKCSH-like PF12999.2 KEY75201.1 - 4.6e-41 140.3 6.9 1.2e-24 86.8 0.3 2.8 3 0 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 KEY75201.1 - 3.4e-30 104.5 0.4 7.4e-30 103.4 0.3 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein MFS_1 PF07690.11 KEY75201.1 - 7.3e-27 93.9 51.4 3.1e-23 82.0 19.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PRKCSH PF07915.8 KEY75201.1 - 1.2e-10 42.0 1.1 3.2e-10 40.6 0.8 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DFF-C PF09033.5 KEY75201.1 - 0.00065 19.5 0.2 0.0013 18.5 0.1 1.4 1 0 0 1 1 1 1 DNA Fragmentation factor 45kDa, C terminal domain DUF3837 PF12939.2 KEY75201.1 - 0.071 13.1 0.1 0.23 11.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) DUF4407 PF14362.1 KEY75201.1 - 0.16 10.8 14.8 1.6 7.6 5.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) CASP_C PF08172.7 KEY75201.1 - 0.3 10.0 3.5 0.61 9.0 2.4 1.4 1 0 0 1 1 1 0 CASP C terminal Flagellar_rod PF05149.7 KEY75201.1 - 0.41 9.7 9.7 1 8.4 6.7 1.6 1 1 0 1 1 1 0 Paraflagellar rod protein OmpH PF03938.9 KEY75201.1 - 2.3 8.1 12.9 1.2 9.0 4.1 2.5 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.14 KEY75201.1 - 3.3 5.4 3.1 5.5 4.7 2.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 KEY75201.1 - 5 6.6 13.6 14 5.2 0.5 3.4 3 0 0 3 3 3 0 Septum formation initiator Ldl_recept_a PF00057.13 KEY75201.1 - 7 6.6 13.2 0.083 12.8 1.2 2.6 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A GCIP PF13324.1 KEY75202.1 - 4.1e-07 29.5 1.1 9.8e-07 28.2 0.5 1.8 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting CDC45 PF02724.9 KEY75202.1 - 0.1 10.5 0.7 0.13 10.2 0.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KEY75202.1 - 0.18 9.7 2.8 0.25 9.2 2.0 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 KEY75202.1 - 1.4 7.9 13.3 2.9 6.9 9.2 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT mRNA_triPase PF02940.10 KEY75205.1 - 1e-55 188.8 0.2 1.4e-55 188.3 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain AA_permease_2 PF13520.1 KEY75206.1 - 3.4e-53 180.7 24.4 6.4e-52 176.5 16.9 2.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEY75206.1 - 4.4e-12 45.1 15.4 1.1e-09 37.1 7.6 2.3 1 1 1 2 2 2 2 Amino acid permease Xan_ur_permease PF00860.15 KEY75207.1 - 1.1e-60 205.2 29.0 1.5e-59 201.4 20.1 2.0 1 1 0 1 1 1 1 Permease family Cupin_4 PF08007.7 KEY75207.1 - 0.035 13.3 0.2 0.062 12.5 0.1 1.3 1 0 0 1 1 1 0 Cupin superfamily protein Pkinase PF00069.20 KEY75209.1 - 0.0097 15.0 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 KEY75210.1 - 1.9e-10 40.1 5.6 0.0011 18.7 0.4 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat CDC45 PF02724.9 KEY75210.1 - 0.1 10.5 12.2 0.14 10.1 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.7 KEY75210.1 - 0.2 10.0 14.1 0.27 9.5 9.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 KEY75210.1 - 0.41 8.5 13.9 0.55 8.0 9.7 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 KEY75210.1 - 2.9 7.0 13.8 4.2 6.5 9.6 1.1 1 0 0 1 1 1 0 SDA1 SURF2 PF05477.6 KEY75210.1 - 6.8 5.7 8.1 10 5.1 5.6 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Cupin_2 PF07883.6 KEY75211.1 - 0.00032 20.1 0.1 0.0006 19.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KEY75211.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.7 1 1 0 1 1 1 0 Cupin Glyco_hydro_18 PF00704.23 KEY75212.1 - 4.5e-44 151.3 0.0 5.5e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GDPD PF03009.12 KEY75213.1 - 3.7e-11 43.0 0.0 2.4e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family MARVEL PF01284.18 KEY75214.1 - 4.9e-12 45.8 29.3 5.9e-12 45.6 20.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain Bac_rhodopsin PF01036.13 KEY75214.1 - 0.17 11.1 18.2 0.22 10.8 12.6 1.1 1 0 0 1 1 1 0 Bacteriorhodopsin-like protein DUF2206 PF09971.4 KEY75214.1 - 7 5.3 7.5 8.5 5.0 5.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Vesiculo_matrix PF06326.7 KEY75215.1 - 0.039 13.3 0.5 0.089 12.2 0.4 1.5 1 0 0 1 1 1 0 Vesiculovirus matrix protein ECM11 PF15463.1 KEY75215.1 - 0.41 10.9 7.9 1.1 9.6 5.5 1.7 1 0 0 1 1 1 0 Extracellular mutant protein 11 Pex16 PF08610.5 KEY75215.1 - 2.4 7.0 5.6 4 6.3 3.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) MARVEL PF01284.18 KEY75216.1 - 1.1e-06 28.5 16.1 1.5e-06 28.1 11.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF3366 PF11846.3 KEY75216.1 - 0.0077 16.1 1.6 0.088 12.6 1.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3366) DUF4293 PF14126.1 KEY75216.1 - 0.031 14.1 6.4 0.061 13.2 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) Polysacc_synt PF01943.12 KEY75216.1 - 0.1 11.8 9.2 0.16 11.1 6.4 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3149 PF11346.3 KEY75216.1 - 1.2 8.7 5.7 4.7 6.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) 7TMR-DISM_7TM PF07695.6 KEY75216.1 - 1.3 8.6 17.2 0.093 12.3 7.2 1.9 2 0 0 2 2 2 0 7TM diverse intracellular signalling UNC-50 PF05216.8 KEY75216.1 - 1.5 7.9 8.2 0.88 8.7 4.1 1.6 1 1 0 1 1 1 0 UNC-50 family DUF1129 PF06570.6 KEY75216.1 - 2.1 7.6 4.6 3.7 6.8 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF1673 PF07895.6 KEY75216.1 - 2.5 7.5 4.8 4.5 6.7 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Diphthamide_syn PF01866.12 KEY75218.1 - 3.6e-50 170.9 0.0 6.3e-50 170.1 0.0 1.3 1 1 0 1 1 1 1 Putative diphthamide synthesis protein MutS_V PF00488.16 KEY75219.1 - 2.1e-80 269.4 0.1 3.8e-80 268.6 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KEY75219.1 - 6.3e-51 173.0 0.1 1.3e-50 172.0 0.0 1.6 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 KEY75219.1 - 2.7e-32 111.1 0.1 7.3e-32 109.7 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 KEY75219.1 - 1e-13 51.2 0.1 2.4e-13 50.0 0.1 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 KEY75219.1 - 3.3e-12 46.6 0.0 2e-11 44.1 0.0 2.4 2 0 0 2 2 2 1 MutS domain II AAA_23 PF13476.1 KEY75219.1 - 0.012 15.9 2.4 0.021 15.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KEY75219.1 - 0.027 14.0 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 KEY75219.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.2 3 0 0 3 3 3 0 AAA domain zf-C2H2_3 PF13878.1 KEY75220.1 - 2.8 7.6 7.0 0.16 11.5 0.4 2.3 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Peptidase_S8 PF00082.17 KEY75222.1 - 9.5e-29 100.4 0.6 1.6e-28 99.6 0.4 1.3 1 1 0 1 1 1 1 Subtilase family F-box-like PF12937.2 KEY75223.1 - 0.056 13.1 3.1 0.061 13.0 0.1 2.6 3 0 0 3 3 3 0 F-box-like CorA PF01544.13 KEY75223.1 - 0.22 10.5 0.2 0.39 9.6 0.2 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FTA2 PF13095.1 KEY75224.1 - 6e-37 127.2 0.0 7.9e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Glyco_hydro_28 PF00295.12 KEY75226.1 - 3.8e-100 335.0 21.5 5e-100 334.6 14.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_16 PF00722.16 KEY75226.1 - 1.7e-10 40.5 0.0 3.8e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 RTBV_P12 PF06361.6 KEY75227.1 - 0.091 13.0 2.0 1 9.6 0.2 2.4 1 1 0 2 2 2 0 Rice tungro bacilliform virus P12 protein CHAT PF12770.2 KEY75228.1 - 2.4e-30 105.6 0.1 4.3e-30 104.8 0.1 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 KEY75228.1 - 2.3e-07 30.6 24.7 0.023 14.6 0.2 7.5 4 3 3 8 8 8 4 Tetratricopeptide repeat Lactamase_B PF00753.22 KEY75229.1 - 1e-14 54.6 3.9 1e-13 51.3 2.7 2.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KEY75229.1 - 2.6e-06 27.1 0.6 3.8e-06 26.5 0.4 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain WD40 PF00400.27 KEY75230.1 - 5.8e-141 453.9 77.2 6.8e-14 51.1 0.2 13.1 13 0 0 13 13 13 12 WD domain, G-beta repeat NACHT PF05729.7 KEY75230.1 - 1.6e-24 86.4 0.1 3.1e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.3 KEY75230.1 - 3e-13 48.7 39.5 0.0038 15.4 0.1 10.9 2 1 7 9 9 9 5 Nucleoporin Nup120/160 HET PF06985.6 KEY75230.1 - 8.3e-13 48.6 5.8 1.2e-08 35.2 0.3 3.0 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Apc4_WD40 PF12894.2 KEY75230.1 - 0.00033 20.0 0.1 19 4.8 0.0 5.9 6 0 0 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain AAA_19 PF13245.1 KEY75230.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Plectin PF00681.15 KEY75230.1 - 0.093 12.2 0.0 54 3.4 0.0 3.8 4 0 0 4 4 4 0 Plectin repeat CXCXC PF03128.9 KEY75230.1 - 0.67 10.2 5.4 0.47 10.7 0.6 3.5 3 0 0 3 3 3 0 CXCXC repeat Stomoxyn PF11585.3 KEY75231.1 - 6.3 6.6 8.2 2.2e+02 1.7 5.7 2.6 1 1 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn Ank_2 PF12796.2 KEY75233.1 - 4.6e-12 46.1 3.3 8.3e-09 35.6 0.3 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEY75233.1 - 1.1e-10 40.7 2.7 0.0013 18.4 0.2 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KEY75233.1 - 1.9e-08 34.5 1.7 0.00023 21.5 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY75233.1 - 3.3e-06 26.8 0.1 0.07 13.4 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KEY75233.1 - 4.8e-06 26.6 2.3 0.0088 16.2 0.2 3.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEY75234.1 - 5.5e-26 90.7 0.1 3.5e-09 36.8 0.0 4.8 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEY75234.1 - 1.2e-17 62.6 7.9 0.0071 16.1 0.0 10.0 11 1 0 11 11 11 4 Ankyrin repeat Ank_4 PF13637.1 KEY75234.1 - 4e-14 52.6 11.3 2.1e-07 31.2 0.5 7.6 6 2 2 8 8 8 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEY75234.1 - 1e-13 50.0 6.4 0.011 15.9 0.0 8.1 9 0 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.1 KEY75234.1 - 3.5e-12 46.1 11.6 3.3e-06 27.1 0.1 6.2 4 2 2 6 6 6 2 Ankyrin repeats (many copies) SGS PF05002.10 KEY75237.1 - 0.0022 17.7 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 SGS domain DUF2968 PF11180.3 KEY75239.1 - 0.067 12.5 0.0 0.087 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) TPR_12 PF13424.1 KEY75240.1 - 1.1e-198 643.7 33.5 1.1e-16 60.4 0.0 14.4 2 1 15 17 17 16 16 Tetratricopeptide repeat TPR_10 PF13374.1 KEY75240.1 - 2.9e-198 637.1 10.8 1.4e-12 47.0 0.0 16.6 16 0 0 16 16 16 16 Tetratricopeptide repeat TPR_4 PF07721.9 KEY75240.1 - 3.6e-40 132.2 0.0 0.68 10.5 0.0 15.8 16 0 0 16 16 15 9 Tetratricopeptide repeat TPR_1 PF00515.23 KEY75240.1 - 5.1e-39 130.3 27.7 0.0051 16.3 0.0 16.2 17 0 0 17 17 16 11 Tetratricopeptide repeat TPR_17 PF13431.1 KEY75240.1 - 1.1e-38 128.2 15.9 0.14 12.4 0.0 16.2 16 0 0 16 16 15 9 Tetratricopeptide repeat TPR_11 PF13414.1 KEY75240.1 - 4.8e-37 125.4 20.0 0.00023 20.7 0.0 9.3 4 2 4 11 11 10 9 TPR repeat TPR_16 PF13432.1 KEY75240.1 - 8.5e-32 109.1 3.9 8.5e-05 23.1 0.0 9.6 3 2 7 11 11 11 10 Tetratricopeptide repeat TPR_7 PF13176.1 KEY75240.1 - 1.1e-27 93.6 32.2 0.032 14.0 0.0 15.8 16 0 0 16 16 15 4 Tetratricopeptide repeat TPR_2 PF07719.12 KEY75240.1 - 1.4e-26 90.2 19.4 0.055 13.4 0.0 15.5 15 0 0 15 15 15 3 Tetratricopeptide repeat PPR PF01535.15 KEY75240.1 - 8.7e-15 53.5 8.2 7.4 6.7 0.0 13.2 15 0 0 15 15 14 0 PPR repeat PPR_2 PF13041.1 KEY75240.1 - 7.4e-14 51.4 0.1 9.3 6.3 0.0 11.5 13 0 0 13 13 12 0 PPR repeat family NB-ARC PF00931.17 KEY75240.1 - 1.5e-13 50.3 0.0 3.1e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.1 KEY75240.1 - 2.2e-11 43.8 31.4 0.019 15.2 0.1 9.8 2 1 12 14 14 14 5 Tetratricopeptide repeat TPR_14 PF13428.1 KEY75240.1 - 6.2e-11 41.9 28.9 2 9.2 0.0 13.7 14 0 0 14 14 14 3 Tetratricopeptide repeat TPR_5 PF12688.2 KEY75240.1 - 9.2e-11 41.8 29.1 0.11 12.5 0.1 8.7 1 1 7 11 11 11 4 Tetratrico peptide repeat TPR_8 PF13181.1 KEY75240.1 - 2.5e-10 39.3 36.5 0.43 10.4 0.0 14.5 15 0 0 15 15 15 3 Tetratricopeptide repeat TPR_15 PF13429.1 KEY75240.1 - 5.2e-10 38.8 20.6 4.5 6.2 0.0 12.7 4 3 10 14 14 14 1 Tetratricopeptide repeat DUF3627 PF12299.3 KEY75240.1 - 2.9e-07 30.4 5.2 3.3 7.8 0.0 10.1 1 1 14 15 15 15 1 Protein of unknown function (DUF3627) NACHT PF05729.7 KEY75240.1 - 3.6e-07 29.9 0.0 1.3e-06 28.2 0.0 2.0 1 0 0 1 1 1 1 NACHT domain PA28_alpha PF02251.13 KEY75240.1 - 3.3e-06 27.1 8.5 25 5.1 0.0 11.2 14 1 1 15 15 13 0 Proteasome activator pa28 alpha subunit TPR_6 PF13174.1 KEY75240.1 - 3.8e-05 23.8 59.1 8.4 7.1 0.1 15.7 16 0 0 16 16 15 0 Tetratricopeptide repeat DUF3366 PF11846.3 KEY75240.1 - 0.00014 21.7 8.0 6.7 6.5 0.0 6.8 1 1 1 6 6 6 0 Domain of unknown function (DUF3366) Abhydrolase_5 PF12695.2 KEY75240.1 - 0.00015 21.5 0.1 0.00076 19.2 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 KEY75240.1 - 0.0012 18.1 0.0 0.016 14.4 0.0 3.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) DUF3878 PF12994.2 KEY75240.1 - 0.0019 17.4 4.1 27 3.7 0.0 6.8 4 3 5 10 10 10 0 Domain of unknown function, E. rectale Gene description (DUF3878) PGAP1 PF07819.8 KEY75240.1 - 0.018 14.6 0.0 0.046 13.3 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 KEY75240.1 - 0.025 14.4 0.0 0.063 13.1 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family PPR_1 PF12854.2 KEY75240.1 - 0.026 13.9 22.6 29 4.2 0.0 11.0 14 0 0 14 14 13 0 PPR repeat AAA_16 PF13191.1 KEY75240.1 - 0.038 13.9 0.0 0.038 13.9 0.0 4.8 2 1 1 4 4 4 0 AAA ATPase domain DUF4477 PF14780.1 KEY75240.1 - 0.13 11.5 13.3 27 4.0 0.0 8.0 1 1 10 12 12 12 0 Domain of unknown function (DUF4477) PAZ PF02170.17 KEY75240.1 - 1 8.6 9.1 2.1e+02 1.1 0.0 8.0 12 0 0 12 12 12 0 PAZ domain DUF721 PF05258.7 KEY75240.1 - 6.2 7.1 19.4 1.3e+02 2.8 0.0 10.2 2 1 12 15 15 13 0 Protein of unknown function (DUF721) rve PF00665.21 KEY75241.1 - 2.4e-06 27.6 0.1 3.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 KEY75244.1 - 3.4e-08 32.9 0.0 6.4e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain SNARE PF05739.14 KEY75246.1 - 8.8e-12 44.5 6.0 8.8e-12 44.5 4.2 3.2 2 1 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KEY75246.1 - 3.8e-05 23.8 10.4 5.5e-05 23.2 1.8 2.4 2 0 0 2 2 2 1 Syntaxin DUF912 PF06024.7 KEY75246.1 - 0.00082 19.3 0.2 0.0025 17.8 0.1 1.8 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) MCPsignal PF00015.16 KEY75246.1 - 0.012 15.1 11.9 0.012 15.1 3.8 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Allexi_40kDa PF05549.6 KEY75246.1 - 0.017 14.4 6.1 0.021 14.1 0.4 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein MitMem_reg PF13012.1 KEY75246.1 - 0.018 15.1 2.3 0.055 13.5 0.3 2.2 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function YukC PF10140.4 KEY75246.1 - 0.021 13.4 0.1 0.036 12.6 0.1 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Lebercilin PF15619.1 KEY75246.1 - 0.026 13.9 1.1 0.026 13.9 0.8 2.8 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease AA_permease_2 PF13520.1 KEY75246.1 - 0.11 10.9 0.8 0.15 10.5 0.5 1.1 1 0 0 1 1 1 0 Amino acid permease Vac_Fusion PF02346.11 KEY75246.1 - 0.14 11.5 2.4 7.2 6.1 0.0 3.2 3 0 0 3 3 3 0 Chordopoxvirus fusion protein DUF2562 PF10814.3 KEY75246.1 - 0.16 11.9 3.3 0.13 12.1 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2562) FH2 PF02181.18 KEY75246.1 - 0.35 9.7 3.9 1.6 7.5 0.1 2.7 2 1 1 3 3 3 0 Formin Homology 2 Domain Spectrin PF00435.16 KEY75246.1 - 0.57 10.4 9.3 2.1 8.7 0.0 3.1 3 1 0 3 3 3 0 Spectrin repeat Syntaxin_2 PF14523.1 KEY75246.1 - 1 9.4 9.0 0.63 10.0 2.5 2.4 2 0 0 2 2 2 0 Syntaxin-like protein GRP PF07172.6 KEY75246.1 - 2.6 8.5 9.0 85 3.7 6.6 2.6 2 0 0 2 2 2 0 Glycine rich protein family DUF2203 PF09969.4 KEY75246.1 - 4.7 7.4 9.0 5.2 7.3 0.9 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) V-SNARE PF05008.10 KEY75246.1 - 5.6 7.2 14.4 0.66 10.1 0.9 3.8 2 2 2 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Memo PF01875.12 KEY75247.1 - 1.9e-69 233.6 0.0 2.2e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Cation_efflux PF01545.16 KEY75248.1 - 2.5e-73 246.6 13.2 2.7e-72 243.2 9.2 2.0 1 1 0 1 1 1 1 Cation efflux family DUF3395 PF11875.3 KEY75249.1 - 1.2e-22 80.1 0.0 2e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 KEY75249.1 - 2.4e-09 36.8 0.0 4e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Cyclin_N PF00134.18 KEY75250.1 - 1.3e-36 124.9 0.3 2.4e-36 124.0 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KEY75250.1 - 6e-11 42.3 0.9 3e-10 40.0 0.2 2.5 2 1 0 2 2 2 1 Cyclin, C-terminal domain Ribosomal_S5 PF00333.15 KEY75252.1 - 2.1e-24 85.0 1.4 3.9e-24 84.1 1.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 KEY75252.1 - 6.8e-21 73.3 0.0 1.4e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Rhodanese PF00581.15 KEY75252.1 - 2.3e-19 69.8 0.0 1.8e-10 41.1 0.0 2.4 2 0 0 2 2 2 2 Rhodanese-like domain FoP_duplication PF13865.1 KEY75252.1 - 0.72 10.3 12.9 0.98 9.9 8.3 1.7 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 zf-Apc11 PF12861.2 KEY75253.1 - 6.4e-44 147.7 10.7 7.5e-44 147.5 7.4 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KEY75253.1 - 6.8e-32 109.4 11.0 8.3e-32 109.1 7.6 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KEY75253.1 - 5.7e-09 35.6 17.2 3.2e-08 33.2 11.9 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KEY75253.1 - 2e-05 24.1 12.7 0.00045 19.8 8.8 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEY75253.1 - 2e-05 24.4 13.3 0.0002 21.3 9.2 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KEY75253.1 - 5.2e-05 23.0 2.3 5.2e-05 23.0 1.6 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KEY75253.1 - 7.7e-05 22.2 15.4 0.00031 20.3 10.7 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KEY75253.1 - 0.0017 17.8 2.6 0.0017 17.8 1.8 2.4 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 KEY75253.1 - 0.0032 16.9 6.5 0.0062 16.0 4.5 1.6 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 KEY75253.1 - 0.0066 16.1 16.7 0.11 12.2 11.8 2.5 1 1 1 2 2 2 1 zinc-RING finger domain zf-HIT PF04438.11 KEY75253.1 - 0.0083 15.7 4.2 0.025 14.2 0.6 2.4 2 0 0 2 2 2 1 HIT zinc finger FANCL_C PF11793.3 KEY75253.1 - 0.0099 15.8 16.3 0.13 12.2 11.3 2.9 1 1 0 1 1 1 1 FANCL C-terminal domain DUF2256 PF10013.4 KEY75253.1 - 0.046 13.4 0.7 0.046 13.4 0.5 3.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF329 PF03884.9 KEY75253.1 - 0.14 11.7 0.6 0.14 11.7 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF329) DiS_P_DiS PF06750.8 KEY75253.1 - 0.5 10.1 2.9 0.74 9.6 0.4 2.1 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain zf-HC5HC2H_2 PF13832.1 KEY75253.1 - 0.97 9.4 10.2 9.6 6.2 7.2 2.2 1 1 1 2 2 2 0 PHD-zinc-finger like domain zf-RING-like PF08746.6 KEY75253.1 - 1.2 9.1 13.7 5.6 7.0 9.5 2.1 1 1 0 1 1 1 0 RING-like domain DZR PF12773.2 KEY75253.1 - 1.4 8.8 13.8 2.6 7.9 4.2 2.2 1 1 1 2 2 2 0 Double zinc ribbon Opy2 PF09463.5 KEY75253.1 - 1.9 8.6 13.9 1.3 9.1 5.1 2.3 2 0 0 2 2 2 0 Opy2 protein zf-RING_UBOX PF13445.1 KEY75253.1 - 2.2 8.0 9.2 1.6 8.4 4.8 2.1 1 1 1 2 2 2 0 RING-type zinc-finger RINGv PF12906.2 KEY75253.1 - 2.6 8.1 15.2 5 7.2 9.6 2.2 1 1 1 2 2 2 0 RING-variant domain zf-HC5HC2H PF13771.1 KEY75253.1 - 2.9 8.0 11.8 1.5 9.0 4.3 2.3 1 1 1 2 2 2 0 PHD-like zinc-binding domain PHD PF00628.24 KEY75253.1 - 3 7.5 15.2 14 5.4 10.5 2.1 1 1 0 1 1 1 0 PHD-finger Elf1 PF05129.8 KEY75253.1 - 7 6.4 7.7 1.1 9.0 0.4 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Pkinase PF00069.20 KEY75254.1 - 4.5e-59 199.7 0.0 5.8e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEY75254.1 - 9.1e-26 90.4 0.0 1.3e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEY75254.1 - 4.9e-07 29.0 0.0 6.6e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEY75254.1 - 0.00012 21.9 0.1 0.33 10.6 0.0 3.0 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 KEY75254.1 - 0.0046 16.0 0.0 0.0076 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.21 KEY75255.1 - 1.5e-48 163.8 0.0 1.9e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEY75255.1 - 0.00028 20.6 0.0 0.00038 20.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KEY75255.1 - 0.00093 19.0 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KEY75255.1 - 0.02 14.5 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain Ribosomal_L31e PF01198.14 KEY75256.1 - 4.1e-35 119.2 1.4 5.2e-35 118.9 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e RGS PF00615.14 KEY75257.1 - 7e-11 42.2 0.0 9e-08 32.2 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain PCI PF01399.22 KEY75258.1 - 1.2e-07 32.0 0.1 5.1e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 PCI domain TMF_DNA_bd PF12329.3 KEY75258.1 - 0.056 13.2 1.4 0.13 12.0 1.0 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding E1-E2_ATPase PF00122.15 KEY75259.1 - 3.1e-53 180.1 0.0 5.9e-53 179.2 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KEY75259.1 - 1.5e-46 159.5 2.4 4e-46 158.1 1.7 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KEY75259.1 - 4.4e-46 154.8 0.1 4.1e-11 42.8 0.0 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 KEY75259.1 - 4.8e-14 52.9 0.1 2.4e-13 50.6 0.0 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEY75259.1 - 2.2e-06 27.4 0.7 9.7e-05 22.0 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FAM70 PF14967.1 KEY75259.1 - 0.016 14.4 0.4 15 4.7 0.0 3.2 3 0 0 3 3 3 0 FAM70 protein DUF1656 PF07869.7 KEY75259.1 - 2.8 7.8 9.3 1.8 8.4 2.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) TPT PF03151.11 KEY75261.1 - 2.9e-22 78.9 10.1 2.9e-22 78.9 7.0 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KEY75261.1 - 3.2e-08 32.8 19.8 4.7e-08 32.3 13.7 1.2 1 0 0 1 1 1 1 UAA transporter family GMP_synt_C PF00958.17 KEY75261.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 GMP synthase C terminal domain EamA PF00892.15 KEY75261.1 - 0.34 10.9 32.3 0.74 9.8 4.5 2.9 2 1 0 2 2 2 0 EamA-like transporter family DUF155 PF02582.9 KEY75262.1 - 4.6e-61 205.7 0.1 6.6e-61 205.2 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 LBP_BPI_CETP_C PF02886.12 KEY75262.1 - 0.13 11.4 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain RasGAP_C PF03836.10 KEY75263.1 - 2.6e-49 166.5 5.5 8.6e-49 164.8 3.8 2.0 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 KEY75263.1 - 1.7e-41 142.0 0.0 5.4e-41 140.4 0.0 1.9 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 KEY75263.1 - 1.6e-11 42.7 49.5 0.0081 15.7 2.7 13.4 14 0 0 14 14 14 7 IQ calmodulin-binding motif CH PF00307.26 KEY75263.1 - 1.6e-10 40.9 0.0 5.7e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain Sulfatase PF00884.18 KEY75264.1 - 5.5e-57 193.2 0.0 7e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 KEY75264.1 - 1.1e-22 79.6 0.3 1.1e-22 79.6 0.2 2.1 3 0 0 3 3 3 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 KEY75264.1 - 1.3e-10 41.2 0.6 6.3e-09 35.6 0.4 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KEY75264.1 - 7.1e-06 24.7 0.0 1.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.7 KEY75264.1 - 0.03 13.1 0.0 0.055 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Metalloenzyme PF01676.13 KEY75264.1 - 0.044 13.1 0.0 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Metalloenzyme superfamily DUF3131 PF11329.3 KEY75264.1 - 0.076 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3131) Med8 PF10232.4 KEY75265.1 - 9.1e-26 90.7 4.3 1.2e-25 90.3 3.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 YPEB PF14620.1 KEY75265.1 - 0.027 13.4 0.3 0.036 13.0 0.2 1.2 1 0 0 1 1 1 0 YpeB sporulation AvrB_AvrC PF05394.6 KEY75265.1 - 0.029 13.3 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Avirulence protein Sporozoite_P67 PF05642.6 KEY75265.1 - 0.1 10.4 1.3 0.14 10.0 0.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CK2S PF15011.1 KEY75265.1 - 0.56 9.9 3.8 0.48 10.1 1.4 1.6 1 1 0 1 1 1 0 Casein Kinase 2 substrate DUF4259 PF14078.1 KEY75265.1 - 7.5 7.0 10.4 0.23 11.9 0.3 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4259) GFA PF04828.9 KEY75268.1 - 1.9e-07 30.8 2.9 6.4e-06 26.0 1.3 2.6 1 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.1 KEY75268.1 - 0.034 14.0 2.6 0.093 12.6 1.8 1.8 1 0 0 1 1 1 0 Cysteine-rich CWC RNase_P_p30 PF01876.11 KEY75270.1 - 6.3e-43 145.5 0.0 1e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 DDE_Tnp_1_7 PF13843.1 KEY75271.1 - 8.3e-26 90.8 0.0 1.1e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 Period_C PF12114.3 KEY75271.1 - 0.73 9.4 5.3 1.2 8.7 3.6 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region WD40 PF00400.27 KEY75272.1 - 4.5e-132 425.7 55.6 3.6e-13 48.8 0.2 12.0 11 2 2 13 13 12 11 WD domain, G-beta repeat Nup160 PF11715.3 KEY75272.1 - 1.8e-11 42.8 21.7 0.16 10.0 0.1 7.9 1 1 5 7 7 7 6 Nucleoporin Nup120/160 NACHT PF05729.7 KEY75272.1 - 6.4e-11 42.1 0.0 1.6e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEY75272.1 - 5.2e-09 36.3 0.1 3e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 KEY75272.1 - 0.00086 18.2 0.0 0.0016 17.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KEY75272.1 - 0.0029 17.7 0.0 0.008 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KEY75272.1 - 0.0039 17.3 0.1 0.021 15.0 0.0 2.2 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 KEY75272.1 - 0.01 14.8 1.1 0.033 13.1 0.3 1.8 1 1 1 2 2 2 1 KAP family P-loop domain AAA_17 PF13207.1 KEY75272.1 - 0.021 15.6 0.0 0.072 13.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEY75272.1 - 0.026 14.8 0.0 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KEY75272.1 - 0.032 13.9 0.1 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase PIF1 PF05970.9 KEY75272.1 - 0.039 12.9 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_19 PF13245.1 KEY75272.1 - 0.065 12.9 0.0 0.51 10.1 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain Lactonase PF10282.4 KEY75273.1 - 9e-06 24.9 0.0 1e-05 24.7 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Fib_succ_major PF09603.5 KEY75276.1 - 0.044 14.2 0.1 0.049 14.1 0.1 1.1 1 0 0 1 1 1 0 Fibrobacter succinogenes major domain (Fib_succ_major) Flg_hook PF02120.11 KEY75277.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Ferric_reduct PF01794.14 KEY75278.1 - 2.1e-16 60.1 5.1 7e-16 58.4 3.5 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KEY75278.1 - 2.3e-16 59.5 0.0 7.1e-16 57.9 0.0 1.8 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KEY75278.1 - 4.4e-13 49.4 0.2 6.1e-10 39.2 0.1 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DUF3723 PF12520.3 KEY75279.1 - 5.7e-99 331.9 1.3 4.3e-98 329.0 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3723) Reo_sigmaC PF04582.7 KEY75279.1 - 1 8.5 5.9 0.91 8.6 2.4 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein SIR2 PF02146.12 KEY75281.1 - 1.7e-08 34.3 0.1 9.1e-07 28.7 0.0 2.2 1 1 0 1 1 1 1 Sir2 family Patatin PF01734.17 KEY75282.1 - 5.1e-09 36.3 0.2 9.2e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3160 PF11369.3 KEY75282.1 - 0.51 8.5 0.0 0.79 7.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) zf-C3HC4_2 PF13923.1 KEY75282.1 - 1.1 9.3 11.2 0.56 10.2 5.6 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEY75282.1 - 4.3 7.1 11.7 0.71 9.6 4.5 2.6 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.1 KEY75282.1 - 4.5 7.1 7.8 22 5.0 5.5 2.2 1 1 0 1 1 1 0 Ring finger domain Phosducin PF02114.11 KEY75283.1 - 8.1e-12 44.4 0.2 3e-11 42.5 0.1 1.7 1 1 0 1 1 1 1 Phosducin Cupin_1 PF00190.17 KEY75284.1 - 2.4e-11 43.2 0.3 3.5e-11 42.7 0.2 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 KEY75284.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Cupin domain Spc7 PF08317.6 KEY75285.1 - 0.0047 15.6 10.4 0.0047 15.6 7.2 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein NYD-SP28_assoc PF14775.1 KEY75285.1 - 0.19 11.4 12.9 0.54 9.9 0.7 3.8 3 1 1 4 4 4 0 Sperm tail C-terminal domain Cep57_MT_bd PF06657.8 KEY75285.1 - 0.5 10.3 22.8 5.5 7.0 5.0 5.2 3 2 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Prefoldin_2 PF01920.15 KEY75285.1 - 0.67 9.7 0.0 0.67 9.7 0.0 5.4 1 1 2 4 4 4 0 Prefoldin subunit RAI1 PF08652.6 KEY75285.1 - 1.2 9.0 4.6 0.26 11.0 0.5 2.0 2 1 0 2 2 2 0 RAI1 like PD-(D/E)XK nuclease GED PF02212.13 KEY75285.1 - 1.6 8.6 11.5 0.17 11.7 3.1 2.8 2 1 0 2 2 2 0 Dynamin GTPase effector domain HALZ PF02183.13 KEY75285.1 - 1.9 8.2 17.9 1.4 8.7 0.7 4.9 3 1 2 5 5 5 0 Homeobox associated leucine zipper Sulfatase_C PF14707.1 KEY75285.1 - 2.8 8.2 6.8 1.7 8.9 0.2 2.9 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase NCD2 PF04905.8 KEY75285.1 - 4.3 7.1 9.9 0.74 9.5 1.7 2.3 1 1 1 2 2 2 0 NAB conserved region 2 (NCD2) MutS_IV PF05190.13 KEY75285.1 - 5.6 7.2 14.7 13 6.0 0.2 4.8 3 1 2 5 5 5 0 MutS family domain IV DUF2681 PF10883.3 KEY75286.1 - 0.12 12.5 1.0 0.19 11.9 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) NAD_binding_6 PF08030.7 KEY75287.1 - 1.5e-11 44.4 0.1 2.9e-11 43.4 0.1 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KEY75287.1 - 5.3e-08 32.6 0.0 1.2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KEY75287.1 - 0.018 15.1 0.6 0.032 14.3 0.1 1.7 2 0 0 2 2 2 0 Ferric reductase like transmembrane component LMBR1 PF04791.11 KEY75287.1 - 0.067 11.7 0.0 0.097 11.2 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Glyco_hydro_16 PF00722.16 KEY75288.1 - 2.7e-14 52.8 0.0 4.7e-14 52.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 KEY75288.1 - 0.00018 19.8 1.3 0.065 11.3 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Velvet PF11754.3 KEY75289.1 - 2.9e-28 98.8 1.6 2.2e-16 60.0 0.0 2.0 1 1 1 2 2 2 2 Velvet factor HET PF06985.6 KEY75290.1 - 6.2e-13 49.0 0.8 6.2e-13 49.0 0.5 3.5 3 2 0 3 3 3 1 Heterokaryon incompatibility protein (HET) NB-ARC PF00931.17 KEY75290.1 - 0.0011 17.8 0.0 0.005 15.7 0.0 1.9 1 1 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.1 KEY75290.1 - 0.016 14.6 0.0 0.046 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KEY75290.1 - 0.032 14.3 0.0 0.34 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain zf-RING_2 PF13639.1 KEY75292.1 - 0.17 11.7 8.1 0.29 10.9 5.6 1.4 1 0 0 1 1 1 0 Ring finger domain SUR7 PF06687.7 KEY75293.1 - 1e-26 93.8 8.2 1.2e-26 93.5 5.7 1.0 1 0 0 1 1 1 1 SUR7/PalI family Methyltransf_33 PF10017.4 KEY75294.1 - 0.0029 17.4 0.0 0.005 16.7 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Nif11 PF07862.6 KEY75295.1 - 0.005 16.7 0.1 0.86 9.6 0.0 2.2 2 0 0 2 2 2 2 Nitrogen fixation protein of unknown function DUF2324 PF10086.4 KEY75297.1 - 0.074 12.2 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative membrane peptidase family (DUF2324) Yip1 PF04893.12 KEY75297.1 - 0.13 11.7 2.1 0.17 11.3 1.5 1.1 1 0 0 1 1 1 0 Yip1 domain Barwin PF00967.12 KEY75299.1 - 0.062 12.9 0.4 2.9 7.6 0.0 2.2 1 1 1 2 2 2 0 Barwin family PAP2 PF01569.16 KEY75302.1 - 5e-11 42.3 0.3 8.5e-11 41.6 0.2 1.3 1 0 0 1 1 1 1 PAP2 superfamily Cu-oxidase PF00394.17 KEY75303.1 - 7.1e-16 58.5 0.3 3.4e-15 56.3 0.1 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 KEY75303.1 - 7.1e-06 25.7 1.5 2.6e-05 23.9 0.1 2.3 3 0 0 3 3 3 1 Multicopper oxidase DUF2846 PF11008.3 KEY75303.1 - 0.14 12.0 0.0 0.63 9.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2846) Tannase PF07519.6 KEY75304.1 - 1.2e-65 222.1 0.3 1.7e-65 221.6 0.2 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 KEY75304.1 - 0.0022 17.2 0.3 0.21 10.7 0.1 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KEY75304.1 - 0.088 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1446 PF07287.6 KEY75306.1 - 1.1e-90 303.7 0.0 1.3e-90 303.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Oxidored_FMN PF00724.15 KEY75307.1 - 2.2e-86 289.9 0.0 3e-86 289.5 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Bac_luciferase PF00296.15 KEY75307.1 - 1.3e-19 70.5 0.2 2.7e-19 69.4 0.2 1.5 1 0 0 1 1 1 1 Luciferase-like monooxygenase Sugarporin_N PF11471.3 KEY75309.1 - 0.0064 16.1 0.1 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension Zn_clus PF00172.13 KEY75309.1 - 0.08 12.8 3.1 0.14 12.0 2.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEY75310.1 - 2.2e-27 95.5 0.0 3.3e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Polysacc_deac_1 PF01522.16 KEY75311.1 - 0.0017 17.9 0.0 0.088 12.4 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide deacetylase ADH_N PF08240.7 KEY75312.1 - 7.4e-11 41.7 0.2 1.5e-09 37.5 0.1 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEY75312.1 - 8.8e-07 28.5 0.1 1.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Transp_cyt_pur PF02133.10 KEY75313.1 - 1e-69 235.2 36.0 2e-64 217.7 20.2 2.0 2 0 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Fun_ATP-synt_8 PF05933.8 KEY75313.1 - 2.4 8.2 8.3 0.18 11.8 0.6 2.9 1 1 1 2 2 2 0 Fungal ATP synthase protein 8 (A6L) DUF3237 PF11578.3 KEY75314.1 - 0.0054 16.0 0.0 0.0066 15.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Methyltransf_12 PF08242.7 KEY75316.1 - 0.0002 21.7 0.0 0.00033 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEY75316.1 - 0.037 13.7 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KEY75316.1 - 0.038 14.5 0.0 0.065 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.12 KEY75316.1 - 0.039 13.3 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.1 KEY75316.1 - 0.059 13.7 0.0 0.12 12.7 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain KR PF08659.5 KEY75317.1 - 3.1e-36 124.7 0.0 5.8e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KEY75317.1 - 1e-29 103.5 0.0 1.7e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Glyco_hydro_61 PF03443.9 KEY75319.1 - 9.8e-69 231.4 0.0 1.2e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KEY75319.1 - 3.2e-11 42.6 11.8 9.3e-11 41.2 8.2 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain NPCBM_assoc PF10633.4 KEY75319.1 - 0.0031 17.5 0.3 0.07 13.1 0.0 2.5 2 0 0 2 2 2 1 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF2655 PF10848.3 KEY75319.1 - 0.12 12.2 0.7 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2655) Toxin_7 PF05980.7 KEY75319.1 - 6.9 6.7 9.2 14 5.7 6.4 1.6 1 0 0 1 1 1 0 Toxin 7 ATP-synt_J PF04911.7 KEY75320.1 - 0.0088 15.4 0.3 0.48 9.9 0.1 2.5 2 0 0 2 2 2 1 ATP synthase j chain ESCRT-II PF05871.7 KEY75320.1 - 0.064 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 ESCRT-II complex subunit F-box-like PF12937.2 KEY75321.1 - 0.012 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 F-box-like SnoaL_2 PF12680.2 KEY75323.1 - 0.0084 16.5 0.3 0.013 15.9 0.2 1.3 1 1 0 1 1 1 1 SnoaL-like domain DUF4319 PF14203.1 KEY75323.1 - 0.11 12.0 1.3 0.27 10.8 0.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4319) KR PF08659.5 KEY75324.1 - 8.6e-27 93.9 0.0 3.7e-19 69.0 0.0 2.1 1 1 1 2 2 2 2 KR domain adh_short PF00106.20 KEY75324.1 - 7.7e-21 74.7 0.0 3.9e-15 56.1 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase Abhydrolase_3 PF07859.8 KEY75325.1 - 4.2e-08 33.0 0.5 2.8e-06 27.0 0.1 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold adh_short PF00106.20 KEY75326.1 - 9e-22 77.7 2.5 9e-22 77.7 1.7 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEY75326.1 - 2.8e-13 49.9 0.4 4.2e-13 49.3 0.2 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KEY75326.1 - 2.4e-05 23.3 0.0 5.1e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KEY75326.1 - 0.00079 18.9 1.5 0.0047 16.3 1.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KEY75326.1 - 0.0015 18.2 0.4 0.0035 17.1 0.3 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_trans_4_4 PF13579.1 KEY75326.1 - 0.044 13.9 3.5 0.52 10.4 0.2 2.3 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain Zn_clus PF00172.13 KEY75328.1 - 0.0085 15.9 8.6 0.099 12.5 0.3 2.4 1 1 1 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain APG6 PF04111.7 KEY75328.1 - 0.071 12.1 0.7 0.075 12.0 0.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 WD40 PF00400.27 KEY75329.1 - 1.3e-190 611.4 40.5 7.5e-14 50.9 0.0 15.1 15 0 0 15 15 15 14 WD domain, G-beta repeat Nup160 PF11715.3 KEY75329.1 - 2.3e-27 95.3 37.3 0.044 11.9 0.1 13.8 1 1 12 13 13 13 13 Nucleoporin Nup120/160 PHZA_PHZB PF03284.8 KEY75329.1 - 1.2e-10 40.6 11.2 5.7 6.0 0.0 11.9 13 1 1 14 14 14 3 Phenazine biosynthesis protein A/B NACHT PF05729.7 KEY75329.1 - 6.5e-10 38.9 0.0 1.9e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEY75329.1 - 5.4e-08 33.0 0.0 2.3e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain PNP_UDP_1 PF01048.15 KEY75329.1 - 6.9e-08 31.7 0.0 2.8e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily Cytochrom_D1 PF02239.11 KEY75329.1 - 0.00016 20.0 7.3 2.7 6.1 0.0 5.1 1 1 4 5 5 5 2 Cytochrome D1 heme domain AAA_19 PF13245.1 KEY75329.1 - 0.01 15.5 0.0 0.045 13.5 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain HTH_20 PF12840.2 KEY75329.1 - 0.019 14.7 0.0 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain KAP_NTPase PF07693.9 KEY75329.1 - 0.024 13.6 0.9 0.079 11.9 0.2 1.6 1 1 1 2 2 2 0 KAP family P-loop domain AAA_22 PF13401.1 KEY75329.1 - 0.05 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEY75329.1 - 0.051 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KEY75329.1 - 0.063 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PIF1 PF05970.9 KEY75329.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase APS_kinase PF01583.15 KEY75329.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Thymidylate_kin PF02223.12 KEY75329.1 - 0.28 10.5 0.0 0.59 9.4 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase